{
    "biomarker_id": "AN6278-2",
    "biomarker_canonical_id": "AN6278",
    "condition": {
        "recommended_name": {
            "id": "DOID:9351",
            "resource": "Disease Ontology",
            "url": "https://disease-ontology.org/term/DOID:9351",
            "name": "diabetes mellitus",
            "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both."
        },
        "synonyms": [
            {
                "id": "DOID:9351",
                "resource": "Disease Ontology",
                "url": "https://disease-ontology.org/term/DOID:9351",
                "name": "diabetes",
                "description": ""
            }
        ],
        "id": "DOID:9351"
    },
    "biomarker_component": [
        {
            "biomarker": "increased IL6 level",
            "assessed_biomarker_entity_id": "P05231-1",
            "assessed_entity_type": "protein",
            "assessed_biomarker_entity": {
                "recommended_name": "Interleukin-6",
                "synonyms": [
                    {
                        "synonym": "Interferon beta-2"
                    },
                    {
                        "synonym": "IFN-beta-2"
                    },
                    {
                        "synonym": "CTL differentiation factor"
                    },
                    {
                        "synonym": "CDF"
                    },
                    {
                        "synonym": "B-cell stimulatory factor 2"
                    },
                    {
                        "synonym": "BSF-2"
                    },
                    {
                        "synonym": "Hybridoma growth factor"
                    }
                ]
            },
            "specimen": [
                {
                    "name": "blood",
                    "namespace": "UBERON",
                    "id": "0000178",
                    "url": "http://purl.obolibrary.org/obo/UBERON_0000178",
                    "loinc_code": "26881-3"
                }
            ],
            "evidence_source": [
                {
                    "id": "AN6278-2",
                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/AN6278-2"
                },
                {
                    "id": "28848164",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/28848164",
                    "tags": [
                        "assessed_biomarker_entity",
                        " assessed_biomarker_entity_id",
                        " biomarker",
                        " specimen"
                    ],
                    "evidence_list": [
                        {
                            "evidence": "Our study is suggestive of S100A8/A9 and IL-6 being related to a persistent diabetes status post-surgically and of different pathophysiological mechanisms being involved in the post-surgical changes in the three groups, despite similar decreases in BMI."
                        }
                    ]
                }
            ]
        }
    ],
    "best_biomarker_role": [
        {
            "role": "prognostic"
        }
    ],
    "evidence_source": [
        {
            "id": "AN6278-2",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6278-2"
        },
        {
            "id": "28848164",
            "database": "PubMed",
            "url": "https://glygen.org/publication/PubMed/28848164",
            "tags": [
                "best_biomarker_role",
                " condition"
            ],
            "evidence_list": [
                {
                    "evidence": "Our study is suggestive of S100A8/A9 and IL-6 being related to a persistent diabetes status post-surgically and of different pathophysiological mechanisms being involved in the post-surgical changes in the three groups, despite similar decreases in BMI."
                }
            ]
        }
    ],
    "crossref": [
        {
            "id": "AN6278-2",
            "database": "BiomarkerKB",
            "url": "https://biomarkerkb.org/biomarker/AN6278-2",
            "categories": [
                "Biomarkers"
            ]
        }
    ],
    "citation": [
        {
            "title": "S100A8/A9 (Calprotectin), Interleukin-6, and C-Reactive Protein in Obesity and Diabetes before and after Roux-en-Y Gastric Bypass Surgery.",
            "journal": "Obesity facts",
            "authors": "Lylloff L, Bathum L, Madsbad S, Grundtvig JLG, Nordgaard-Lassen I, Fenger M",
            "date": "2017",
            "reference": [
                {
                    "type": "PubMed",
                    "id": "28848164",
                    "url": "https://glygen.org/publication/PubMed/28848164"
                }
            ],
            "evidence": [
                {
                    "id": "AN6278-4",
                    "database": "BiomarkerKB",
                    "url": "https://biomarkerkb.org/biomarker/AN6278-2"
                }
            ]
        }
    ],
    "section_stats": [
        {
            "table_id": "biomarker_component",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                }
            ],
            "sort_fields": [
                "biomarker",
                "assessed_biomarker_entity_id",
                "assessed_entity_type",
                "assessed_biomarker_entity.recommended_name"
            ]
        },
        {
            "table_id": "citation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                }
            ],
            "sort_fields": [
                "title",
                "journal",
                "authors",
                "date"
            ]
        }
    ]
}