[ { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121108-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G5E8K6-1", "uniprot_id": "MOT6_MOUSE", "id": "G5E8K6-1", "name": "Monocarboxylate transporter 6", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARALEQADGRWAWVVLLSSLVTQALTLGFPTCIGVFFTDLQRDFQA---SNSETSWFPSILGAMVHGGGPLCSILVKHFGCRVTMMLGGVLASLGMVVSTFSGSLTHLFLTAGVITGLGMCFSFQSSITVVGLYFVRRRPLANALASMGLSMGVTLWPLLARYLLETLG-WRGAFLIFGGILLHCCVCGALLRPVA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TNEVPEPKEDPLLPPKIPTRSCLA----TCVSTIRYHLAFDILRHNMGFCIYVTGVTWMNLGFALPHIFLVPYAMHHGVDDYWAAMLMSIVGFCNIFLRPMAGLLLAGRKSLAAYRKYLFAVAILINGLTNLICTVSADFRVLLGYCLVYSLSMCGVGILVFQVLMDIVPMDRFPSALGLFTILCGVTSLISPPLAGLLLD---KTNNFSYVFYMSSGFLVSGSLILGVGFYAAEKKK-LKQDGQAKMENATSEMTPMHDLTSEDKD-------SAKKQP------------------------YPESIYMTNV---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A3B5-1", "uniprot_id": "D4A3B5_RAT", "id": "D4A3B5-1", "name": "Monocarboxylate transporter 6", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQALEQADGRWAWVVLLASLVTQALTVGFPSCIGVFFTDLQRDFQA---SNSETSWFPSIMGAMLHCGGPLCSILIKRFGCRVTMMLGGVLASLGMVASTFSDSLIHLFLTAGLITGLGMCFSFQSSITVVGLYFVRQRPLANALASIGISMGVTLWPLLARYLLETLG-WRGAFLIFGGIFLHCCVCGAMLRPVA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TNVDPEPKEDLLLPPKTPTRSCLA----TCVSTIQYYLAFDILRHNMVFCIYVTGATWMTLGFSLPHIFLVPYAMHHGMEEYWAAMLMSIVGFCNIFLRPVAG-MLAGRKSLAAYRKYLFAVAILINGLTNLICTVSADFRVLLGYCLVYSLSMCGTGILVFQVLMDIVPMDRFPSALGLFTILCGMGSLISPPLAGLLLD---TTNNFNYVFYMSSGLLISASLFMGVGFYVAEKK--LKQDRQAKMEDATSEITSKHSLTSEDKD-------SAKKQP------------------------YPENIYVTSV---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15375-1", "uniprot_id": "MOT6_HUMAN", "id": "O15375-1", "name": "Monocarboxylate transporter 6", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPQALERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQA---SNSETSWFPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLG-WRGTFLVFGGIFLHCCICGAIIRPVA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSVAPETKECPPPPPETPALGCLA----ACGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAG-LMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLD---ATNNFSYVFYMSSFFLISAALFMGGSFYALQKK---EQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGCPASSRTSHEWLLWPKAVLQAKQTALGWNSPT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FB53-1", "uniprot_id": "E7FB53_DANRE", "id": "E7FB53-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MAPQQPSSMEEQSGELCEPESEELEKQGPGPPSNAN-------------APDSYDAPDGGWGWVVLLATIIVLALTLAFPSCIIIFYLDLQKEFEA---TNSQTSWVPSIMTAVLHAGGPLCSVLVDRFGCRATVMFGGVLSGFGMAVSSFSHSIVDLYITAGVITGLGFCFSFQPAVTILGHYFVRRRPFANAMSSTGTALGLSTLPFLCDFLKIELG-WRGSFLVLGAVLLNCCVCGAVMRPIR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PRKPRKTNEINNSPKTSDKKGCMLGICQSLASSLRQQMAFDLFCSNTRFRVFSLGITWMMLGFVVPLIYLVPYASADDMDPSRAALLLSILGFVNIFVRPPVG-VLFSLPWFKGRHIYVFSAALLINGLSNSICCISASFPVLLVYVLTYGLSMSVVGSLMFTVLMDTVEMSRFPSALGLLSIMESVTLLIGPPLAGFLVD---RTQLYTYVFMACTIIVVLSALFLMFTFYWLDSRDAAKKDSPAKPAINISTDCQYSSVPIDGDK---------TNKP------------------------SSETENTTCV---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W509-1", "uniprot_id": "Q9W509_DROME", "id": "Q9W509-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MVHG---PPARRKSQQQ-------HEACEMDMERQP------------------------TPPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNE---GKGYTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYG-WRGAMLIIGGIVLNCIIFGAMFRPL----------------------------------------ELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLP---------------------KDQYLQLPQRTDTAVSGGALCRS----NSVGHNLKPNLNNNSN----------GAVNGQGPTLVT------------PPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRE----RSASGTMYRP----DALYQGSLHNLPDYVSS------RNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRIILG-YISDKPWVN--RLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYD---LTDSYAPAFLMAGLMIAISGLVMFAIPPLQRLQVRKSERKPHTEHLALS----------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0L6-1", "uniprot_id": "Q9W0L6_DROME", "id": "Q9W0L6-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------MVDTNSSNPGIVGGNSASSARLRRFERTDSELACEEAARLTAEQSPEDEDNQDNDEDDDDEE-SVYGELPPPPDGGYGWVICFASFMCNMIVDGIAYTFGIFLEEFVAYFHE---GKGTVAWVGSLLSGVYLSAGPIVSALANKYGCRAVCIAGSIIACIAFVLSTFSTNVSMLMATYGFMGGFGFGMIYLPAVVAVGYYFETKRSLATGIAVCGSGFGTFAFAPLATYLLEEYG-WKNALLIFAGLILNCAIFGAMMRPLTYPKKKKQKPLMQRMYEEKQLQLERGSFAGSHFMVQLPDGTIERKLKMPLNADPGVHSSLNLELLAQQAGGGGLHPVSTLPTITESKVVDVHRQNGAQSPPNGDSNGQLSARSAAGAVGRRPHRNSESENSPYHSQDAMTRNASQPAFLAGDHQSLPKNGSVPAFNTRVRKTSASERFQPSLAAIRATSRGDLEAGAGGDFASSKLSLSQRQGGSQTGSSGRMVRPMSRKDIFYSGSVTNLPQYQSQKSLANYRNSVLSLTKYEKSMQSVAKLDPLAEAEKHREEYDLCPCLGIPDSVKSVVNTMLDVSLLKDPVFMLIGVSNIFGMAGLYVPFVYLVDAAKEHDIPKNDAAMLLSIIGITNTVGRVFCG-WVADLPQVN--SLLLNNCCLLVSTIAVTLTPLCYSYAAYITMSIFFGLAISGYISLTSIILVDLLGLDKLTNAFGLLILFRGFAALIGTPLAGAIYD---MTHTYDLPFYMAGALFGISTITSFLAPCLKRCSPSE-ETPVHVETLTPIDEEQGEDAEDDEDQPITIVPKIIKTLASPQQEEGHP--------------QFPQKTSESKL---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08268-1", "uniprot_id": "MCH4_YEAST", "id": "Q08268-1", "name": "Probable transporter MCH4", "aln": "-------------------------------------------------------------------------------------------------------------------MLNIPIIANSKRFLFSKDHEAQSTRDHDVELETREGPSSGYNPNFNAADAILKKNSDQVDLDVNKLTNVTSRVLNTPEASL-IYDDDREFPDGGLKAWLVVFGAFMGLVPVFGLINSLGAIESYISKHQLAN-ISSSTISWIFSLYLAISFLSCILSGGYFDRNGSIGLMCTGTVIYAGGLFALANCKSVWQFILAFSVCSGLGTGILMTPLIGTVATWFLKRRGIATSISTMGGSIGGIVFPIMLRKLYKEVG-FQWAIRILSFICLTCLICASVLARER------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TKPVVQPFKSKAEVAKWYIS------------SVFNWRYFLEGKFLFVAIGASFAESSLTSCATYLASYSMTRGNTENVAYTMITASNAVGILGRYIPG--YFADKFIGRFNVEIITISMAALFNFVMWLPFGGNTKVLWAYVCLWGFSTGSILSLTPVCIGQISKTTDFGKRYATVYLLQALVTIPVLPIGGTLIG---KGTVANYN----HFIIFNSALMAAGAACYIISRHICVGAKLCKF---------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53918-1", "uniprot_id": "ESBP6_YEAST", "id": "P53918-1", "name": "Uncharacterized transporter ESBP6", "aln": "MSTHSNDYFSASSGMVSETSSEVSSINSSQPVSFSKASIAAPVPCSDLHSTKSNDASRKLSISRTLTNRLNDIKKAVDDDNLQTEENSADVNKILESRFDVADAIRLQHNESVQSKLNIPVTHTTTAGASLSAPSSSAFSASSIQNDTTEHKASMDSKLMRNRLYPASTKHSGKDLEAQGITEFEPDEPTVKKVFTNKSTGQLELPPDGGYGWVVTFCVFLTMFSTWGCNASFGVDLAYYLNHDTYPGASKYDYALIAGLTVFLGQLLSPLVMALMRIIGLRTTMLFGDAVMLAAYLLASFTTKLWQLYVTQGFMVGCSISLIFVPATTVLPGWFLKKRAVAMGVSLLGTGAGGVVYGLATNKMLSDFGNTRWCLRIIGISCSISVLVAIALLKER------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NPTPAIGLKSPRAMFEQLKA-------------MFSLKVITKPFVVLIALWFMFALFAYNMMVFTLSSYAISKGLSSHDASTLTAILNGSQSIGRPLMG---LAGDKFGRANVTIVLTTLLTIYMFAFWIP-AHTFVQLIFFSILVGSCVGVANVMNTVLIADMVKPEEFLPAWAFVNYCGAPFLLVCEVIAQALTVEKDKSNPYLHAQIFCGCCFIAALILISILREYSIRMKLTERQAMTNEKLKEWKASEYDTDSADEDWGKLKERKTKYDLLLGPG----------------IKKYFLRMVYPMKV---------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* .*:: : :: . . : . : . .: : : * * : .: : : .. * . : . : :* :* .* .:: * . * : * : : ::. . : . : : . . . : : * : : . . * * . : : . : : : : . . . : :. : . . : ", "identical_positions": 14, "similar_positions": 73, "identity": "1.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121109-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96QS3-1", "uniprot_id": "ARX_HUMAN", "id": "Q96QS3-1", "name": "Homeobox protein ARX", "aln": "MSNQYQEEGCSERPECKSKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLTSRADPEKAVQGSPKSSSAPFEAELHLPPKLRRLYGPGGGRLLQGAAAAAAAAAAAAAAA-ATATAGPRGEAPPPPPPTARPGERPDGAGAAAAAAAAAAAAWDTLKISQAPQVSISRSKSYRENGAPFVPPPPALDELGGPGGVTHPEERLGVAGGPGSAPAAGGGTGTEDDEEELLEDEEDEDEEEELLEDDEEELLEDDARALLKEPRRCPVAATG---AVAAAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFPP-HHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTP--AVEGAVASGALADPATAAADRRASSIAALRLKAKEHAAQLTQLNILPGTSTGKEVC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35085-1", "uniprot_id": "ARX_MOUSE", "id": "O35085-1", "name": "Homeobox protein ARX", "aln": "MSNQYQEEGCSERPECKSKSPTLLSSYCIDSILGRRSPCKMRLLGAAQSLPAPLASRADQEKAMQGSPKSSSAPFEAELHLPPKLRRLYGPGGGRLLQGAAAAAAAAAAAAAAATATGTAGPRGEVPPPPPPAARPGERQDSAG--AVAAAAAAAAWDTLKISQAPQVSISRSKSYRENGAPFVPPPPALDELSGPGGVAHPEERLSAASGPGSAPAAGGGTGAEDDEEELLEDEEDEEEEEELLEDDDEELLEDDARALLKEPRRCSVATTGTVAAAAAAAAAAVATEGGELSPKEELLLHPEDAEGKDGEDSVCLSAGSDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDASPFPP-HHPALDSAWTAAAAAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLFSTMAPLTSASTAAALLRQPTP--AVEGAVASGALADPATAAADRRASSIAALRLKAKEHAAQLTQLNILPGTSTGKEVC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2KXF6-1", "uniprot_id": "A0A0G2KXF6_DANRE", "id": "A0A0G2KXF6-1", "name": "", "aln": "MSSEVEED-NPEQTNCRCKTPTLLSSYCIDSILGRKSPLKV-----------------------QETPHS-LWPLHPHMHLPPKLRRPFAP-------------------LTDSSTDETAGPR----------------------------LLQTACEKLKITEASIVNISRAGSYQEHASCKNTP---------------------------------------------INEEEGAD-------------ICGETNVTLKQER-------------------------------EAFLKNSEETS---------LSAGSDTEDGMLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWFQNRRAKWRKREKVGVQPHTLSLHYSGAPPAAQSLCHYLSGNPFVPNPHPAIDSAWP-------APFQRLAQPAQNSVSPP-----GFSALLGAAMFRHPAFFNPTFGRLFTSLGPMALQRIPLPAIEGPIQRSHLTTSLLSSSPPLPSSPTVDLRASSIAALRLKAKEHSAQLTHITAAG--TAGKEEC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.: :*: .*:.:*:.*:***************:** *: * :*:* *:...:******** :.* : : : ***** :* :.***::*. *.***: **:*:.: .* :::**. : : .::.. **: * * :* :.*::. ******:*:*:*****************************************************************.*.*.*. .* :.*. .*::.*. **...** * ***:****. *.* *. *. .: ** *:*::****:******:.*:*****:::.*:: . . :. * : :: *.: . *::.:.* ***************:****::. ::*** *", "identical_positions": 207, "similar_positions": 116, "identity": "36.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121113-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K2W6-1", "uniprot_id": "PHF13_MOUSE", "id": "Q8K2W6-1", "name": "PHD finger protein 13", "aln": "MDSD-SCAAAFHPEEYSPTCKRRRTVEDFNKFCTFVLAYAGYIPYPKEELPLRSSPSPANSTAGTIDSDGWDTG---FSDITPSVP----DRCFS-HLQPS-----LLQRAKPSNYLLD-RKTTDKLKKKKR-RKRRDSD--------IPVKEGFRESLLKLEAADP--YVETPSSPTMQDIP-QASADPCSGWDS--------DTPSSGSCATVSPDQ-----------------VTEIKTEGKRTIVRQGKQVVFRDEDSTGNDEDIMVDSDDDSWDLVTCFCMKPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVFVCQKCRDSKFDIRRSNRSRMGSRKLFLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86YI8-1", "uniprot_id": "PHF13_HUMAN", "id": "Q86YI8-1", "name": "PHD finger protein 13", "aln": "MDSD-SCAAAFHPEEYSPSCKRRRTVEDFNKFCTFVLAYAGYIPYPKEELPLRSSPSPANSTAGTIDSDGWDAG---FSDIASSVPLPVSDRCFS-HLQPT-----LLQRAKPSNFLLD-RKKTDKLKKKKK-RKRRDSD--------APGKEGYRGGLLKLEAADP--YVETPTSPTLQDIP-QAPSDPCSGWDS--------DTPSSGSCATVSPDQ-----------------VKEIKTEGKRTIVRQGKQVVFRDEDSTGNDEDIMVDSDDDSWDLVTCFCMKPFAGRPMIECNECHTWIHLSCAKIRKSNVPEVFVCQKCRDSKFDIRRSNRSRTGSRKLFLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2L648-1", "uniprot_id": "A0A0G2L648_DANRE", "id": "A0A0G2L648-1", "name": "PHD finger protein 13", "aln": "MDVDGSTTCPFDKQGYSSTFKRKRTVEDFNKFCTFVLAYAGYIPYPQEEAHLRNSSSPPNSTGSTADSDGWDNQQLSCSLSSPDEPPPKNRKSFAGFKRPTSEDSEPQKRPKSAGLLLEGRKKADKVKKKKKLRKCKDEDFRNFAPFTPPRVEGEFSSLGRSIKEEPEDYISIPVPSTGFDHPAHTCSKPVSSSQSSAVCKEEPDIEHSCWGGSKSSDQEFEDVKKPSKLEREAMVLKEESFSAKRTVVRQGKQVVFRDEDGSADDEDIMVDSDDDSWDLVTCFCMKPFAGRAMIECNQCNTWIHLSCAKIRKSNVPETYICQRCKDSKFDIRRSNRSRVGSRKHLLD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * * :..*. : **.: **:***********************:** **.*.**.***..* ****** * :.. * :.*: . :*: :*.*.:. **: **.:**:****: ** :*.* * ** .* : :* *:. * ..* * * :: :.* *. :* * * .: *.** :.* . ..***:*************.:.:***************************.*****:*:*****************.::**:*:************* **** :**", "identical_positions": 176, "similar_positions": 70, "identity": "50.57%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121114-10", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O94967-1", "uniprot_id": "WDR47_HUMAN", "id": "O94967-1", "name": "WD repeat-containing protein 47", "aln": "MTAEETVNVKEVEIIKLILDFLNSKKLHISMLALEKESGVINGLFSDDMLFLRQLILDGQWDEVLQFIQPLECMEKFDKKRFRYIILKQKFLEALCVNNAMSAEDEPQHLEFTMQEAVQCLHALEEYCPSKDDYSKLCLLLTLPRLTNHAEFKDWNPSTARVHCFEEACVMVAEFIPADRKLSEAGFKASNNRLFQLVMKGLLYECCVEFCQSKATGEEITESEVLLGIDLLCGNGCDDLDLSLLSWLQNLPSSVFSCAFEQKMLNIHVDKLLKPTKAAYADLLTPLISKLSPYPSSPMRRPQSADAYMTRSLNPALDGLTCGLTSHDKRISDLGNKTSPMSHSFANFHYPGVQNLSRSLMLENTECHSIYEESPERDTPVDAQRPIGSEILGQSSVSEKEPANGAQNPGPAKQEKNELRDSTEQFQEYYRQRLRYQQHLEQKEQQRQIYQQMLLEGGVNQEDGPDQ--QQNLTEQFLNRSIQKLGELNIGMDGLGNEVSALNQQCNGSKGNGSNGSSVTSFTTPPQDSSQRLTHDASNIHTSTPRNPGSTNHIPFLEESPCGSQISSEHSVIKPPLGDSPGSLSRSKGEEDDKSKKQFVCINILEDTQAVRAVAFHPAGGLYAVGSNSKTLRVCAYPDVIDPSAHETPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQGDLTKQLPIMVVGEHKDKVIQCRWHTQDLSFLSSSADRTVTLWTYNG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IYD3-1", "uniprot_id": "A0A0R4IYD3_DANRE", "id": "A0A0R4IYD3-1", "name": "", "aln": "MTAEEIINIKEAEIIKLILDFLNSRKLHISMLALEKESGIINGLYSDDMLFLRQLVLDGQWEEVLQFIQPLEGLDKFDRKRFRYIILKQKFLEALCVNNAISASDDPENLELTMQDAVKCLHSLEEFCPSKEDYSKLCLLLTLPRLTNHAEFKDWNPSTARVHCFEEACTMVAEFIPADRKLSEAGFKASGDRLFQLLIKGILYECCVEFCQSKATGEEISEEEVLLAVDVLCGNGCEELDLSLLSWLQNLSSTVFACAFEQKTLNIHVDRLVKPARTGHADLLTPLLTKLSPCPASPLRRPHSADTYMSRSLNPALDGLSHGLVGREKKNTEGDGKATAMSQSFANFGYPSGGNGSK-------NGSTVCTDSPDRAQAETINSPGGTNSIRPPLTPGKD---GGVTATADKSE--------EQLQEFQRQRLRVQQHLEQKQQQRQLYHQMLLEGGVHPPDQPTDTAQHNLTQKFLNRSIQKLEELNVGMEDLGEDVQALAQQCNGTSASESS-------KQTPETGPGRIK---TAVISSTP-HKGGVRGIPSLDESP----VLVNQSVFQ-----------------DEKPKSPFIAVQTLEDTQAVRAVAFHPSGMLYAIGSNSKTLRVCTYPQSLKTSPQAPVKQPDICFKRIKHHKGSIYCVAWSPCGQLLATGSNDKYVKVLPFNADTCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILISAGAGDCNIYTTDCQRGQGLHALSGHTGHILSLYTWGGWMIASGSQDKTVRFWDLRVPSCVKVVGTTLHGTGSAVASVAIDPSGRLMATGLEDCRCMLYDIRGGRSVQVYRPHSSDVRSVRFSPGAHYLLTGSYDSRVMISDLQGDLTKNLPVTVVAEHADKVIQCRWHTRDLSFLSSSADKTVTLWAHQT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** :*:**.************:**************:****:**********:*****:********** ::***:*********************:**.*:*::**:***:**:***:***:****:*************************************.********************.:*****::**:******************:*.****.:*:******::************.*:**:****** ******:*:**:::.:*******::**** *:**:***:***:**:**********: **..::*: :: ..*::.**:***** **. * *: : :: :**:* . : * *:: : . .. *: *. .. . *.* **:**: ***** *******:****:*:********: * * : *:***::********* ***:**:.**::*.** *****:... *. . .*: .. *:. : : :*** : *... ** *:*** : ::**:: *:*.*. *:.:: **************:* ***:**********:**: :..*.: . *** : *** ***********************************:******************************************************************:****.************************:*****:***********:******:*** **. ********** ** *:************************ :: ::********:**: **.** **********:**********:*****::: ", "identical_positions": 635, "similar_positions": 167, "identity": "68.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121114-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63312-1", "uniprot_id": "PHLB1_RAT", "id": "Q63312-1", "name": "Pleckstrin homology-like domain family B member 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LTLGARGRRTRSPSPTLGES--LAPRKGSFSGRLSPAYSLGSLTGASPRQSPHAQRKLSSG--DLRVPIP--RERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPETGELPSIGEATAALALAGRRPSRG--LAGAIVVSGRSGEESGGASQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLAVEEERAQVLGRVEQLKVRVKELEQQLQEAAREAEMERALLQGEREAERALLQKEQRAMDQLQEKLVALETGIQKERDKE-------------------------------------------ADALETETKLFEDLEFQQLERES----RVEEERELAGQGLLRSKAELLRSVSKRKERLAVLDSQAGQIRAQAVQESERLAREKNAVLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLK----------------------------------------------------EVYRS-KMNGDMASPLPRTR------------------------------------------------------SGPLPSSSGSSSSSS-------------------------------QLSVATLGRSPSPKSALLAQNGTSSLPRNLAATLQDIETKRQLALQQKVELPPAEPLSPEDPAGHQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAAFPAGP--SGFPTLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACS-PDNMSSASGLDMGKIEEMEKMLKEAHAEKSRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKLREKQFSQARPLTRYLPNRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLIKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAK-----------SPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PDH0-1", "uniprot_id": "PHLB1_MOUSE", "id": "Q6PDH0-1", "name": "Pleckstrin homology-like domain family B member 1", "aln": "--------------------------------MDPLNRSQLGPGCKTQAVVQKGPLDLIETGQGLKVQTDKPHLVSLGSGRLSTAITLLPLEEGRTVIG-SAARDISLQGPGLAPEHCYIENLRG-TLTLYPCGN-ACTIDGLPVRQPTRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGVRAPGPTYNPGSAESESLVNGNHTAQPAT----RAPSACASHSSLVSSIEKDLQEIMDSLVLEEP---GAAGKKPAAT----SPLSPMANGG-RYLLSPPTSPGAMSVGSSYENTSPAFSPLSSP--ASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRP-----------SGSRSSDSPRLGRKGGHERPPSP--GLRGLLTDSPAATVLAEARRTTESPRLGG-QLPVVAISLSEYPSSGARSQPASIPGSPKFQSPVPAPRNKIGTLQDRPPSPFREPPGTERVLTSSPSRQLVGRT---------------FSDGLAATRTLQPPESPRLGRRGLD--SMRELPPLSPSLSRRALSPLP-----ARTAPDPKLSREVAESPRPRRWAAHGTSPEDFSLTLGARGRRTRSPSPTLGES--LAPRKGSFSGRLSPAYSLGSLTGASPRQSPRAQRKLSSG--DLRVPIP--RERKNSITEISDNEDELLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPETGELPSIGEATAALALAGRRPSRG--LAGAIVVSGRCGEESGGASQRLWESMERSDEENLKEECSSTESTQQEHEDAPGAKHQGEVLAVEEERAQVLGRVEQLKIRVKELEQQLQEAAREAEMERALLQGEREAERASLQKEQRAVDQLQEKLVALETGIQKDRDKE-------------------------------------------ADALETETKLFEDLEFQQLERES----RVEEERELAGQGLLRSKAELLRSVSKRKERLAVLDSQAGQIRAQAVQESERLAREKNAALQLLQKEKEKLNVLERRYHSLTGGRPFPKTTSTLKEMEKLL-----LPAVDLEQWYQELMSGLGTGLAAASPRSSPPPLPAKASRQLQVYRS-KMDSDAASPLPRTR------------------------------------------------------SGPLPSSSGSSSSSS-------------------------------QLSVATLGRSPSPKSALLAQNGTSSLPRNLAATLQDIETKRQLALQQK---------------GHQVIEEQRRRLAELKQKAAAEAQCQWDALHGAGPFSAGP--SGFPALMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACS-PDNMSSASGLDMGKIEEMEKMLKEAHAEKSRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKLREKQFSQARPLTRYLPNRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLIKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAK-----------SPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86UU1-1", "uniprot_id": "PHLB1_HUMAN", "id": "Q86UU1-1", "name": "Pleckstrin homology-like domain family B member 1", "aln": "--------------------------------MDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTAITLLPLEEGRTVIG-SAARDISLQGPGLAPEHCYIENLRG-TLTLYPCGN-ACTIDGLPVRQPTRLTQGCMLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTPQTAT----RGPSACASHSSLVSSIEKDLQEIMDSLVLEEP---GAAGKKPAAT----SPLSPMANGG-RYLLSPPTSPGAMSVGSSYENTSPAFSPLSSP--ASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRP-----------SGARS-ESPRLSRKGGHERPPSP--GLRGLLTDSPAATVLAEARRATESPRLGG-QLPVVAISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSERVLTTSPSRQLVGRT---------------FSDG-LATRTLQPPESPRLGRRGLD--SMRELPPLSPSLSRRALSPLP-----TRTTPDPKLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGES--LAPHKGSFSGRLSPAYSLGSLTGASPCQSPCVQRKLSSG--DLRVPVT--RERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRG--LAG---ASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKE-------------------------------------------AEALETETKLFEDLEFQQLERES----RVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLL-----LPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRS-KMDGEATSPLPRTR------------------------------------------------------SGPLPSSSGSSSSSS-------------------------------QLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQK---------------GQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGP--SGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACS-PDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAKKRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HCC6-1", "uniprot_id": "A0AC58HCC6_DANRE", "id": "A0AC58HCC6-1", "name": "Pleckstrin homology-like domain family B member 1", "aln": "MRSHVEGLVSLAARKLLQDSHVPEQVSDSTLAMDTLNQN-LSHGHQSHQVLQSTPLDLIETGKALKVQAERPHLVSLGSGRLSTAITLLPLPEGKTTVG-HGAMDISIQGPGVAAQHCFIENRAG-IITLHPCGN-QCSMDGLPVNKPVRLSQGCMLCFGQSAFFRFNHPEEAFRMKSMMPEGG-QTASVKNWTHKDSENLVNGNHSSGEAKSHLVSNERVRPEHSAIVSSIEKDLQDIMDSLVMDDPQPSSSESKKPSSQSISQSPLSPMLNGGGRFLLSPPTSPGAMSVGSSYENNSPPFSPLSSPSAASSGSYTTLSPIGCQDQPHMLPPVPVRSSSYNYTSQPPIPQPRTILPSYSSGSSGPKVPESPRLQRKALLEAPPSPKPSRRGLNQDSSVAKTPDSPIQTHILPSVSISTAPTDVPSVSRVPVPGSPRLATKFSTASSPASPSSPRTKTTIVLQDRPSSPFREQPQPDRSLTSSPSHQLSPPSRSFQPPLDPIVHIIQGGPSHPHPRTLQPPESPRLARRNLEGSSMRELPPLSPSIARRGVPVLPGALPGTLRTPESPSPRMVPESPRLRRKTGS-----PTEEPFSPRAMRTRSPSPTSGLTGESSGRKGSFGNSLSSAFSLSSLPGSSPRSSPRSHRKMSAGHRDLRMPHPGMRERKNSITEISDNEDDLLEYHRRQREERLREQEMERLERQRLETILNLCAEYNKGDGPPGDLGRMGVSGLGSRDGLNVRRPSMDSVNSASLRATQRQRESQEDNLKEDSSSTESAQLDGRTPALLNGQNGQAEESLGSGSIGRLELGYLEEERVRVLAKVDELKARITELEQQLQESKQEAEMERALLQGERQAEMEQIETETEIINQLQRKLTELESSIQREKDKERANVDAEREALERLQDGYNELTSQLHNCPESLREQLQEQLKREAETLEAATKQFEDLEFQQLERES----SLEEERETISQQLMQDRAQYHSSVAKRKEKVVALESQASQLGIQAAQECERLAKDRTITLQMLHKEKERLASLERRYQSLTGGKTFPKSSNTIKEEYLKLSDVYKMYGSECHDIQLASASSHGLSLALDPAETAPREEYVTVGQLNQMYGMPKVESSPTSPVQSVQPSLADFPRLPSPHGSSLSLSFERQSDWGRPQMPVLDLEHWYQEVMAAGDVNQLCPPPLPAKAFSSSSSSPRRPVQVYRSRLDSDCSQSLLRPKVSAGLSPTYTTATLGRNTPSRSPLMVANSTGSLPRNLAATLQDIETKRQLALQQK---------------GQQVIEEQRRRLAELKQKAAVEAQCQWEALHGSQTQLHQPFSSSPAPALHHSILHHTAP-----PCGEQPYDTLSLESSDSMDTSISTGNNSACS-PDNMSSASGMDALKIEEMEKMLKEAQLEKARLIESRERETQSRKLMLEEERRRREEAEKRLQEETLHRQQLIEKEVKMRARNFSQARPMTRYLPIRKEEFDLRSHIESSGHSVDTCYHVILTEKMCKGFLVKMGGKIKSWKKRWFVFDRLKRTFSYYADKHESKLKGVIYFQAIEEVYYDHLRSATKKGFFNLN-LTNSPTPTLTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VX80-1", "uniprot_id": "Q9VX80_DROME", "id": "Q9VX80-1", "name": "PH domain-containing protein", "aln": "-------------------------------------------------------MSLTKKDPSLRVAASDPHLVSLGGGRLSTAVTIHYIHIGDTTIGSAASCSISLNGSGVRPLHCTIYRSDANEVTLVPEKDSRLLIDGAPILEETKLSQGAMITIGNSNYLRFNNPDEAQMMRSAMGSNERISMPQIDFTQSARQAHELS------------QSLELESFYESIINPINNPSTYELECPKVFSS-------------------DLVTVNMPAKDVLGQKYASFARNLAENHRNEKQLNNQYAKGVGSNGGYWN----------------VPSNAAIYKEQHQQQHQQAP---------------QDLLTKVNNDRYDRYPKAG-GLQIYSMNGVNSDINNGPATGNNSGTGGGAELEDMLKICTEYADRNNSMPSTHNVSSTSSITSSPIVQNRIKTNGSLPRDKNKSPFPQQAGVASSANISLLSSS-----------------SGYENVRLLGPNRVEINGQIHVP-----------------------------ASAGDGGSSSGVSSNALAP----------TAAVRASHENLNQNHSATTGGKYVPQSPRTKIRTNCMSPKKDVSFGNAFALAISPPPLASSAVVSTSKPIPIP------------SMVKPPLAPKPPAPNQQRDYEQLFKSFERKQQQLDRMVPAKRSNKNINNLTLNLQSVESQTQS-----PKPSRK--------------------PAPAPRSIHLEQRQRRELIQRRKQLKRELAELPPSAGIEGLELKLGE---QPLAPSASPRLQLQALQNRVCRLEAQRNATRVMEENQQAKLKQSIEIKQDQLKKLRAMLKQKPNNACLKEELQ-----------------------------------------LVCESLESDRKTFEDLEFQYFEEESEHHASHEEFKRQEQRLMLEAELAALRIQIGPDEEEPGSPTSPGSTGSNLVNGVMSQSLFGSAELLCPKRRNQEDLMSKSVNENMFYNHKIEANTSTPKRLPLQL----------FEDLAGGSCEQISFNLSLQGDRFEVNPLERRVPSQDDIDRSCKVANDAPISASQGAS-----------------------------------------------------TKIFDSIMEIERNRK---------------------------LLLAQQGHQVIEHERQKMYDLKKKSHDEARTQYLLSTQQSMEQQRQLESDAN--------------GGKDAKLFEKTELQKLNQKPGEPVDDQVQKIAGDKENNVQN-----RKSTGSSPTTTTTTTTGGGTTPQQQRHSQPELEHHAIALGIGGGGSGGAGGANQMVARSPRPLSEANNCDATIEAPKFANG--MDSSASPAVADNKRASSNSQDTASAGSGSGNSGSGGSTASDRKRVLP----KHQRPLTRYLPIFSPDLNLRHHIETAGHQIDPCPHVFVDAHSCRGYLHKLGATFHAWSRRWFVLDRQRSALIYYSDKSERKPRGGAYFATIDEVYLDHLNASKS------------GRPHCTFIVKTKKRSYNLQAASDSAARIWIDAIITGAQGNLDY--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . .:.* * : :. . :*. .:. . : ** . : . :* . * : * .::* ** :: :**:: : : *: .. : .: :** * . : : : : . ..: . : * : *. . : :: *:::: . : : *.: :.:: :: : :.:*: * .. ..: : .::**: * ******* :*.** ** :. : ::. . .*. :.... : .: : . * ::.::. : ..: .: : .:.* * :: *: .. . . . : : . . . .: :. * . : .: * :* *.:* :*** : : *::. :: .* :*:**.. .: * : : * * .. :: .: . . .:: .*. *...... .::* : * : :: : :: .: : ::* . ..: : .. .. . ::: : .: **:***** . :::*: ***::** :*.* **.: : *:*:* *:*..:::*.:****:** : :: ** ** * * :* ** :*:*** ***.:: . * ** ***:.* * : *.* .* ***:*.*:***:* :: ", "identical_positions": 129, "similar_positions": 261, "identity": "7.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121114-9", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WU61-1", "uniprot_id": "CLCC1_RAT", "id": "Q9WU61-1", "name": "Chloride channel CLIC-like protein 1", "aln": "---------MLCSLLLCGCLLLIT-------GYAHDDDWIDPTDMLNYDAASGTMRKSQ----AKYGTSEKKEVNP---GLSDAQELSDCLQRLDSLTHKVDDCEKKKMKDYES-QSNPVFRRYLNKILIEAGKLGLPDEDRVDVRYDAEILLTRQTLLEIQKFLSGEE-WKPGALDDALSDILTNFKSHDAEAWKWQFEDYFGVDPYNVFMVLLCLLCIVALVATELWTYVRWHTQLKRVCIISFLVSLGWNWIYLYKVAFAQHQANVAKMAPLNDVCA--KKMDWTENLWEWFRISWTYKDDPCQKYYELLIVNPIWLVPPTKALAVTFTNFVTEPLKYIGKGTGEFIKALMKEIPVLLQIPVLVILALAVLGFCYGAGQS----VPMLRHFRGPEREPPRALEPDDRRRQKELDYRFHGGAGDADFSYR-----GPAG-SIEQGPYDKMHVCERDVLRQRQVNMRFPSGNKSPEVLRAFD--LPD--TEAQEHPEVVPS--HKPSIVNTSLKETSELPRESTL----AECSQCAKDGSGQVPS-TAESSPIVEK-------AQLKTDSECRP----HSTEA-AAAAARGTD---------PVSSPCG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LI2-1", "uniprot_id": "CLCC1_MOUSE", "id": "Q99LI2-1", "name": "Chloride channel CLIC-like protein 1", "aln": "---------MLCRLLLCECLLLIT-------GYAHDDDWIDPTDMLNYDAASGTMRKSQ----VRSGTSEKKEVSP---DSSEAEELSDCLHRLDSLTHKVDSCEKKKMKDYES-QSNPVFRRYLNKILIEAGKLGLPDENKVEMRYDAEILLSRQTLLEIQKFLSGEE-WKPGALDDALSDILINFKCHDSEAWKWQFEDYFGVDPYNVFMVLLCLLCLVVLVATELWTYVRWYTQMKRIFIISFLLSLAWNWIYLYKMAFAQHQANIAGMEPFDNLCA--KKMDWTGSLWEWFTSSWTYKDDPCQKYYELLIVNPIWLVPPTKALAITFTNFVTEPLKHIGKGAGEFIKALMKEIPVLLQIPVLAILALAVLSFCYGAGRS----VPMLRHFGGPDREPPRALEPDDRRRQKGLDYRLHGGAGDADFSYR-----GPAG-SIEQGPYDKMHASKRDALRQR-----FHSGNKSPEVLRAFD--LPD--TEAQEHPEVVPS--HKSPIMNTNL-ETGELPGESTP----TEYSQSAKDVSGQVPS-AGKSSPTVDK-------AQLKTDSECSPPGGCPPSKE-AAVAAHGTE---------PVSSPCG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96S66-1", "uniprot_id": "CLCC1_HUMAN", "id": "Q96S66-1", "name": "Chloride channel CLIC-like protein 1", "aln": "---------MLCSLLLCECLLLVA-------GYAHDDDWIDPTDMLNYDAASGTMRKSQ----AKYGISGEKDVSP---DLSCADEISECYHKLDSLTYKIDECEKKKREDYES-QSNPVFRRYLNKILIEAGKLGLPDENKGDMHYDAEIILKRETLLEIQKFLNGED-WKPGALDDALSDILINFKFHDFETWKWRFEDSFGVDPYNVLMVLLCLLCIVVLVATELWTYVRWYTQLRRVLIISFLFSLGWNWMYLYKLAFAQHQAEVAKMEPLNNVCA--KKMDWTGSIWEWFRSSWTYKDDPCQKYYELLLVNPIWLVPPTKALAVTFTTFVTEPLKHIGKGTGEFIKALMKEIPALLHLPVLIIMALAILSFCYGAGKS----VHVLRHIGGPESEPPQALRPRDRRRQEEIDYRPDGGAGDADFHYR-----GQMG-PTEQGPYAKTYEGRREILRERDVDLRFQTGNKSPEVLRAFD--VPD--AEAREHPTVVPS--HKSPVLDTKPKETGGILGEGTPKESSTESSQSAKPVSGQDTSGNTEGSPAAEK-------AQLKSEAAGSPDQGSTYSPARGVAGPRGQD---------PVSSPCG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q3S9-1", "uniprot_id": "CLCC1_DANRE", "id": "A0A2R8Q3S9-1", "name": "Chloride channel CLIC-like protein 1", "aln": "MKLSSSSSFGLCILVVFFCFVVIESAKIRIDGYN-DEAWIDPYDMLNYDPTTKRMRKSTESESYQNVPTKRREFNSESCDVPKCPDEHECIKKLHILQKEFDEQKSKSTATLSKPVCLPVFKRFLSKLLKETSKLGLPDDGITAMHYDAEVKLSKQSLAEIQKLLNDEDGWTTGAMDEALSQILVQFKLHDYEAWKWRFEDTFHVDVDTVLKVSLIVLIIVAIICTQLWSVVSWFVQFRRMFAVSFFISLIWNWFHLYMLAFAEHKKNIVQVESFNAKCTGLKQLNWQDSLSEWYRRTWTLQDDPCKKYYEVLVVNPILLVPPTKAITITITNFITDPLKHIGEGISEFLRALLKDLPVTLQIPVLIIIILAILIFVYGSAQAAIHQVARFPRLGWRQEQPPPAVGQRQNPQLRAHEEPWEGGDARQPLPMRQDNRGNHVGNRGDQGFRDANAPENREEDRSMDIRQEFSTKRTPVETLQATGNTFPDDETDSQQRTQELDSGANVEEEVKVEEKEKKESFSVDNKEQKETKSPDRSEPITSEPPSSIDVKTVGADQGNEHLMCTKRKWAAQNGFKLQVILCEINSEASADLPEEEECFSFKHPVQETQS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** *:: *:::: ** *: **** ******.:: **** : : .::... . . . : :* ::*. * :.*. :.*. .. . ***:*:*.*:* *:.******:. ::****: *.:::* ****:*..*: *..**:*:***:** :** ** *:***:*** * ** .*: * * :* :*.::.*:**: * *..*::*: :**:.** ***::** :***:*: ::. : .:: *: *:::* .: **: :** :****:****:*:**** *******:::*:*.*:*:***:**:* .**::**:*::*. *::*** *: **:* * **:.:: * : :: : :** *: :. : . : .** . : * . * :** .*: *. * : ... *.*:* . .** ::::::. : * : :... *. .. :: .: :: :.: .* : .:: :: * : . ... : **... .", "identical_positions": 178, "similar_positions": 197, "identity": "29.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121116-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NUD9-1", "uniprot_id": "PIGV_HUMAN", "id": "Q9NUD9-1", "name": "GPI alpha-1,6-mannosyltransferase 2", "aln": "-------------MWPQDPSR--KEVLRFAVSCRILTLMLQALFNAIIPDHHAEAFSPPRLAPSGFVDQLVEGLLGGLSHWDAEHFLFIAEHGYLYEHNFAFFPGFPLAL-LVGTELLRPLRGLLSLRSCLLISVASLNFLFFMLAAVALHDLGCLVLHCPHQSFYAALLFCLSPANVFLAAGYSEALFALLTFSAMGQLERGRVWTSVLLFAFATGVRSNGLVSVGFLMHSQCQGFFSSLTMLNPLRQ----------LFKLMASLFLSVFTLGLPFALFQYYAYTQFCLPGSARPIPEPLVQLAVDKGYRIAEGNEPP--WCFWDVPLIYSYIQDVYWNVGFLKYYELKQVPNFLLAAPVAILVAWATWTYVTTHPWLCLTLGLQRSKNNKTLEKPDLGFLSPQVFVYVVHAAVLLLFGGLCMHVQVLTRFLGSSTPIMYWFPAHLLQDQEPLLRSLKTVPWKPLAEDS--PPGQKVPR-----NPIMGLLYHWKTCSPVTRYILGYFLTYWLLGLLLHCNFLPWT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TPN3-1", "uniprot_id": "PIGV_MOUSE", "id": "Q7TPN3-1", "name": "GPI alpha-1,6-mannosyltransferase 2", "aln": "-------------MGLLDPSQ--KEVLRFAVNCRILTLVLQALFNLIIPDHHADAFCPPRLAPSGSADQLVEGLLGGLSRWDAEHFLFIAEHGYLYEHNFAFFPGFPLAL-LMGTELLRPLQGLLSQRSCLLVSVALLNLLFSVLAAVALHDLGCLVLHCPRQALCAALLFCISPANVFLAAGYSEALFAFLTFSAMGQLERGRGWASGLLFALAAGVRSNGLVSLGFLLHSQCRGFCSSLAVLSPWKP----------LVKLMASVCLSVLIVSLPFALFQYRAYIQFCSPGSAPSIPEPLLQLAADKGYRLAGENAPP--WCSWDLPLIYNYIQDVYWNVGLLRYYELKQVPNFLLATPVTVLVVWATWTYVTTHPWLCLTLGLQRTKDRENPEKPHRGFLSPKVFVYLVHAAALLVFGGLCMHVQVLTRFLASSTPIMYWFPAHLLQDQEPLLRCVDTEPGKLPQEKS--PPGQKAPR-----NCLMKLFYDWKRCSPVTRCVLVYFLTYWLLGLILHCNFLPWT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4ITR4-1", "uniprot_id": "A0A0R4ITR4_DANRE", "id": "A0A0R4ITR4-1", "name": "GPI mannosyltransferase 2", "aln": "MSCCHCPQLKLSSMTLFNKNEDIQTVLRCATFTRLISLFLQAVLNVVIPDHVADAFSPPRSEAPLLLDPLIEALFGGLSHWDAEHFLFIAERGYIYEHNFAFFPLFPFILRLLASTLLWPLCGFLTMRGRLIITVVIGNSFLFVLSAVALYSLSRIVLQERKLAFVAVMMYCLTPANVFMLAGYSETLFATLTFAGLWMLERRYTVGACLLFGFATGARANGLVNVGFLLYLTLQRCLARARAFNKVAEGVQYHNYIWELVRFAFTGAVYAALVALPFGLFQFYGFQTFCHPTSN-QIPPALVNLAQHKGYRVADAASPKPKWCHWQIPLLYSYIQDVYWDVGFLRYFQWKQIPNFILALPVATLGFKALFIYITDNPVFCMYLGLGEKGNS----KKIYGFCNPRVFVYIVHNTVLLLFGIFCMHVQVLTRFLASSSPVLYWVSGHLLFKYEPLLKEEKLFRSDQTQQKKNHKPGLRCFAGMWRNNPVFYLLMHWKTCSIYTQCILGYFISYWFLGLALHCNFLPWT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .. : *** *. *:::*.***::* :**** *:**.*** .. * *:*.*:****:***********:**:********* **: * *:.: ** ** *:*: *. *:::*. * :: :*:****:.*. :**: : :: *.:::*::*****: *****:*** ***:.: *** : ***.:*:*.*:****.:***:: : : :. *.:: : : . :.***.***: .: ** * * ** .*::** .****:* * ** *::**:*.*******:**:*:*:: **:***:** **: * * : *:* :* :*: *** .. : * ** .*:****:** :.**:** :***********.**:*::**...*** . ****: . . :.. ** : * :: *: .** ** *: :* **::**:*** *********", "identical_positions": 227, "similar_positions": 138, "identity": "42.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121116-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZXW7-1", "uniprot_id": "A0A8I5ZXW7_RAT", "id": "A0A8I5ZXW7-1", "name": "", "aln": "----MPYSRISLRNSLDGGFLLSDDSSLCPVDLKLPSTPIGPLKTMLLVDREMANPEVVVSSCSSHQDESPCTFYPS-----SSQSEQLLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDR--------MDDTYAVYTQNDVYDQIIFAVTRYLQLRNISVGNHAYENKGTKQSAMAVCQHFYRQGTICPGNDTFDIDPEVETDCFLIEPEEAFHMGTPGENKLNLTLDFHRLLTVELQFKLKAINLQTVR-HQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECK-DWHVSGSIQKNTHYMMIFDAFVILTCLSSLVLCARSVIRGLQLQQEFVNFFLLHYKKEVSASDQMEFINGWYIMIIVSDILTIVGSILKMEIQAKSLTS--YDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPYHEKFRSLNKVSECLFSLINGDDMFSTFAKMQQKSYLVWLFSRVYLYSFISLFIYMILSLFIALITDTYETIKHYQQDGFPETELRKFIAECKDLPNSG---KYRLEDDPPGS------LFCCCKK----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4F0-1", "uniprot_id": "MCLN3_MOUSE", "id": "Q8R4F0-1", "name": "Mucolipin-3", "aln": "----------------------------------------------------MANPEVLVSSCRARQDESPCTFHPS-----SSPSEQLLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDR--------MDDTYAVYTQSEVYDQIIFAVTQYLQLQNISVGNHAYENKGTKQSAMAICQHFYRQGTICPGNDTFDIDPEVETECFLVEPDEASHLGTPGENKLNLSLDFHRLLTVELQFKLKAINLQTVR-HQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIKECK-DWHVSGSIQKNTHYMMIFDAFVILTCLASLVLCARSVIRGLQLQQEFVNFFLLHYKKEVSASDQMEFINGWYIMIIISDILTIVGSVLKMEIQAKSLTS--YDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVMRFCCCAAMIYLGYCFCGWIVLGPYHEKFRSLNRVSECLFSLINGDDMFSTFAKMQQKSYLVWLFSRVYLYSFISLFIYMILSLFIALITDTYETIKHYQQDGFPETELRKFIAECKDLPNSG---KYRLEDDPPGS------LLCCCKK----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDD5-1", "uniprot_id": "MCLN3_HUMAN", "id": "Q8TDD5-1", "name": "Mucolipin-3", "aln": "----------------------------------------------------MADPEVVVSSCSSHEEENRCNFNQQ-----TSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDR--------MDDTYAVYTQSDVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPEIETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVR-HQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECK-DWHVSGSIQKNTHYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKMEIQAKSLTS--YDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSG---KYRLEDDPPVS------LFCCCKK----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P7U6-1", "uniprot_id": "A0A8M9P7U6_DANRE", "id": "A0A8M9P7U6-1", "name": "", "aln": "-----------------------------------------------------------MSDRASHTHESATLLDPE-----CVES--------LRRKLKYFFMSPCQKYSTRGRIPWKMMLQILKIVIITVQLVSFGLSNEMMVTFKEENLIAFKHFFLKNYKD---------SNKHYALYTKHEVHDHILYTIRRYLQLQNLTIGNQALEMIDGLATPLSLCQQLYRHARVVPSNETFEIDPHVETECVSVYPLSPITTDS-LENSLNLTLDFQRLLAVNIYLKIKAINIQTVR-HQELPDCYDFSINIMFDNRAHSGQIKISLSSGVQINVCK-DWNISGSTDSHFALIVVFDCLIICFCLLSLILCTRSVHTGFLLQTEYRRFMSSQHSKSVSWSERLEFINGWYILIIISDALTIAGSILKICIQSKELTS--YDVCSILLGTATMLVWIGVMRYLSFFQKYYILILTLKAALPNVIRFSICAVMIYLSYCFCGWIVLGPHHENFRTFSRVAGCLFSMINGDEIYSTFTKLREYSTLVWLFSRLYVYSFIPVFTYMVLSVFIALITDTYETIRHYQKHGAPLSELQAFIADCRDPRNYD---KNTTNEDEESS------SFCCLCAPCVFCT----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VW35-1", "uniprot_id": "Q9VW35_DROME", "id": "Q9VW35-1", "name": "", "aln": "MQSYGPGAQTAPAVKRRTDSYEAAQQQQQSPESDEEYVNTRILRRQVQLQSTPVAPVVPMPISAGSGTAPPSVDGREEQPEFPGSSAASYQEERMRRKLQFFFMNPIEKWQAKRKFPYKFVVQIVKIFLVTMQLCLFAHSRYNHINYTGDNRFAFSHLFLRGWDSSREVESYPPAVGPFALYLKSEFFDTVQYAVNGYANVS-RSIGPYDYPTPNNTMPPLKLCLQNYREGTIFGFNESYIFDPHIDEVCERLPPNVTTIGVENYLRQRDVEVNFASLVSAQLTFKIKTVNFKANGGPLSAPDCFRFDISITFNNRDHDGQMLLSLDAEATRLKCHGATDFISDANFDSMLRSVLNIFVLLTCALSFALCTRALWRAYLLRCTTVNFFRSQFGKELSFDGRLEFVNFWYIMIIFNDVLLIIGSALKEQIEGRYLVVDQWDTCSLFLGIGNLLVWFGVLRYLGFFKTYNVVILTLKKAAPKILRFLIAALLIYAGFVFCGWLILGPYHMKFRSLATTSECLFALINGDDMFATFATLSSKATWLWWFCQIYLYSFISLYIYVVLSLFIAVIMDAYDTIKAYYKDGFPTTDLKAFVGTRTAEDISSGVFMTDLDDFDQTSFLDVVKSICCCGRCGRHQEPAQPNSGYTSLSSIMK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . . * :****::***.* :*: :: : *:*: :**:** ::*:** *. *. : :. :* :**.*:**:.: . :*:* : :..* : ::: * :: ::* . ..: :* : *:.. : *::: :**.:: * : * . .. :: ::* *::.:: :*:*::*::: . ***: * :.* *:*: *.*:: :**. *: .. .. : . ::: ::: * *: ** *:: . *: .*: :. *.:* . ::**:* ***:**..* * * ** ** *:.: *. :*.**::** ..:***:**:***.** .* ::****: * *:::** .* :** .: ****::***:* :**:: .: ***::****::::**:.: . : :* *.::*:****.:: *::**:***:* *:*:**: * :.* * ::*: *:. . :: * :** ", "identical_positions": 154, "similar_positions": 196, "identity": "23.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121116-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2ANX3-1", "uniprot_id": "A2ANX3_MOUSE", "id": "A2ANX3-1", "name": "Phospholipid-transporting ATPase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMFCNKKKLLEVERVVKANDRDYNEKFQYADNRIHTSKYNVLTFLPINLFEQLQRVANAYFLFLLILQLIPEISSLTWFTTIVPLVLVISMTAVKDATDDYFRHKSDNQVNNRQSKVLINSKLQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRQALPVTSELGADISSLAEFDGIVRCEAPNNKLDRFSGVLSWKDSKHALSNQKIILRGCVLRNTSWCFGMVLFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLVCLGIILAVGSSILESEVGDQFRTPPFWREGE------KSFLFSGFLTFWSYVIILNTLVPISLYVSVEVIRLGHSYFINWDRKMYYASKAMPAEARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKKCSINGRVYAGEVLDDPIQKKEITKEK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EATDFSSKSKSEKTLHFFDQSLMESIELGDPKVHEFLRLLALCHTVMSEENSAGQLVYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTPVTYQLLAFLDFNNIRKRMSVIVRNPEGRIKLYSKGADTILFEKLHPSNEDLQSLTSDHLSEFAGEGLRTLAIAYRELDDKYFKMWQKMLEDANSATLERDERISGLYEEIERDLMLLGATAVEDKLQEGVIETITSLSLANIKIWILTGDKQETAINIGYACNVLTDAMDALFVITGNTAGEVREELRKAKENLLGQ-----------------------------------------------------------STSFSNGHAVYDNKQRLGLDAGAGEAVTG--------EYALVINGHSLAHALESDVENDLLELACVCKTVVCCRVTPLQKAQVVELVKKHRNAVTLAIGDGANDVSMIKSAHIGIGISGQEGLQAVLASDYALAQFRYLQRLLLVHGRWSYYRMCKFLCYFFYKNFAFTLVHFWFAFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGMFDQDINEQNSMDYPQLYEPGQLNLLFNKRRFFICVAHGIYTSLALFFIPYGAFYNVAAEDGQHIADLQSFAVTVATSLVIVVSIQIALDTSYWTVVNHVFIWGSVATYFSILLAMHSDGVFGIFPRHFPFVGNARHSLSQKFVWLVVLLTAVTSVMPVVVVRFLKMYLYPSLSDQIRR--WQKAQRKKRPLRSRRPQTRR-SSSRRSGYAFAHQEGYGELITSGKNMRAK------SPAPASGLEKKLYNNTSWIENLCKKTTDAVSGFSHDKTVKL-------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1B0GWR9-1", "uniprot_id": "A0A1B0GWR9_RAT", "id": "A0A1B0GWR9-1", "name": "Phospholipid-transporting ATPase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMFCNEKKLLEVERVVKANDRDYNEKFQYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLFLLILQLIPEISSLTWFTTIVPLVLVISMTAVKDATDDFFRHKSDNQVNNRQSEVLINSKLQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRQALPVTSELGADISSLAKFDGIVICEAPNNKLDRFSGVLSWKDSKHTLSNQKIILRGCVLRNTSWCFGMVLFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLVCLGIILAVGNSIWESEVGNQFRTSLFWREGE------KSSLFSGFLTFWSYVIILNTLVPISLYVSVEVIRLGHSYFINWDRKMYYAAKAMPAEARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKKCSINGRVYAGEVLDDLDQKKEITKKK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EAVDFSGKSKSERTLHFFDHSLMESIELGDPKVHEFLRLLALCHTVMSEEDSAGQLVYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTPVTYQLLAFLDFNNIRKRMSVIVRNPEGQIKLYSKGADTILFEKLHPSNEDLLSLTSDHLSEFAGEGLRTLAIAYRELDDKYFKMWQKMLEDANSAIAERDERISGLYEEIERDLMLLGATAVEDKLQEGVIETITSLSLANIKIWILTGDKQETAINIGYACNVLTDAMDAVFVITGNTAVEVREELRKAKENLLGQ-----------------------------------------------------------NTSFSNGHAVYENKQRLELDSGAGETVTG--------EYALVINGHSLAHALESDVEKDLLELACVCKTVVCCRVTPLQKAQVVELVKKHRNAVTLAIGDGANDVSMIKSAHIGIGISGQEGLQAVLASDYALAQFRYLQRLLLVHGRWSYYRMCKFLCYFFYKNFAFTLVHFWFAFYCGFSAQTVYDQWFITLFNIVYTSLPVLAMGVFDQDVSEQNSMDCPQLYEPGQLNLLFNKRRFFICVAHGIYTSLILFFIPYGAFYNVAAEDGQHIADYQSFAVTVATSLVIVVSVQIALDTSYWTVVNHVFIWGSVATYFSILLAMHSDGVFGIFPRQFPFVGNARRSLSQKFVWLVVLLTAVTSVMPVVVFRFLKMHLYPSLSDQIRR--WQKAQRKERPLRSRRPQTRR-SSSRRSGYAFAHQEGYGELITSGKNMRAK------SPAPTSGLEKMLYSNTSWIGNLCKKTTDVVSGFSHDKTVKL-------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TF62-1", "uniprot_id": "AT8B4_HUMAN", "id": "Q8TF62-1", "name": "Probable phospholipid-transporting ATPase IM", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFCSEKKLREVERIVKANDREYNEKFQYADNRIHTSKYNILTFLPINLFEQFQRVANAYFLCLLILQLIPEISSLTWFTTIVPLVLVITMTAVKDATDDYFRHKSDNQVNNRQSEVLINSKLQNEKWMNVKVGDIIKLENNQFVAADLLLLSSSEPHGLCYVETAELDGETNLKVRHALSVTSELGADISRLAGFDGIVVCEVPNNKLDKFMGILSWKDSKHSLNNEKIILRGCILRNTSWCFGMVIFAGPDTKLMQNSGKTKFKRTSIDRLMNTLVLWIFGFLICLGIILAIGNSIWESQTGDQFRTFLFWNEGE------KSSVFSGFLTFWSYIIILNTVVPISLYVSVEVIRLGHSYFINWDRKMYYSRKAIPAVARTTTLNEELGQIEYIFSDKTGTLTQNIMTFKRCSINGRIYG-EVHDDLDQKTEITQEK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPVDFSVKSQADREFQFFDHHLMESIKMGDPKVHEFLRLLALCHTVMSEENSAGELIYQVQSPDEGALVTAARNFGFIFKSRTPETITIEELGTLVTYQLLAFLDFNNTRKRMSVIVRNPEGQIKLYSKGADTILFEKLHPSNEVLLSLTSDHLSEFAGEGLRTLAIAYRDLDDKYFKEWHKMLEDANAATEERDERIAGLYEEIERDLMLLGATAVEDKLQEGVIETVTSLSLANIKIWVLTGDKQETAINIGYACNMLTDDMNDVFVIAGNNAVEVREELRKAKQNLFGQ-----------------------------------------------------------NRNFSNGHVVCEKKQQLELDSIVEETITG--------DYALIINGHSLAHALESDVKNDLLELACMCKTVICCRVTPLQKAQVVELVKKYRNAVTLAIGDGANDVSMIKSAHIGVGISGQEGLQAVLASDYSFAQFRYLQRLLLVHGRWSYFRMCKFLCYFFYKNFAFTLVHFWFGFFCGFSAQTVYDQWFITLFNIVYTSLPVLAMGIFDQDVSDQNSVDCPQLYKPGQLNLLFNKRKFFICVLHGIYTSLVLFFIPYGAFYNVAGEDGQHIADYQSFAVTMATSLVIVVSVQIALDTSYWTFINHVFIWGSIAIYFSILFTMHSNGIFGIFPNQFPFVGNARHSLTQKCIWLVILLTTVASVMPVVAFRFLKVDLYPTLSDQIRR--WQKAQKKARPPSSRRPRTRR-SSSRRSGYAFAHQEGYGELITSGKNMRAK------NPPPTSGLEKTHYNSTSWIENLCKKTTDTVSSFSQDKTVKL-------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TEK0-1", "uniprot_id": "A0A8N7TEK0_DANRE", "id": "A0A8N7TEK0-1", "name": "Phospholipid-transporting ATPase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MDGACFRETLRTRRRWPGVMAIWKKDVHIEEERHVRANDRDYNERFSYADNRIKTAKYNVFTFLPINLFEQFQRFANAYFLVLLILQLIPEISSLSWFTTIVPLVLVLAITAVKDATDDYFRHKSDQQVNTRQSQVLIKGKLQNEKWMNVRVGDVIKLENNQFVAADLLLLSSSEPYGLCYIETAELDGETNLKVRQALTVTSDLGDDVAKLADFNGEVICEPPNNKLDKFIGTLYWKDNKYPLDNEKMLLRGCVLRNTEWCFGLVIFAGLQTKLMQNCGRTKFKRTSIDKLMNTLVLWIFGFLICMGIILAIGNTIWEQSVGSDFWAYLQWKELT------VNAVFSGFLTFWSYIIILNTVVPISLYVSVEVLRLGHSYFINWDRRMYYSRKDTPAEARTTTLNEELGQVEFIFSDKTGTLTQNIMVFNKCSINGKTYG-DVFDEFGHKVDITEKT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PCVDFSFNPLMDRKFRFHDSSLVEAIKLEEPLVQEFFRLLALCHTVMPEERNEGELVYQAQSPDEGALVTAARNFGFVFRSRTPETITLYEMGQAVTYQLLAILDFNNVRKRMSVIVRNPKGQLKLYSKGADTILFDRLDPSNEELMFTTSEHLNEFAGEGLRTLALAYKDLDEDVFDEWTKKLLFASTALDNREEKLGALYEEIEQGMMLLGATAIEDKLQEGVPETIACLTLANIKIWVLTGDKLETAMNIGYSCNMLRDDMNEVFIISGHTMLEVQQELRTAKERIMGP-----------------------------------------------------------SKDKFSSGLDMEKTELYSVDSVFEETIIA--------EYALIINGHSLAHALEAELEQILVDVACLCKSVICCRVTPLQKALVVELIKRHKRAVTLAIGDGANDVSMIKTAHIGVGISGQEGMQAVLASDYSFAQFRYLQRLLLVHGRWSYHRMCNFLCYFFYKNFAFTLVHFWYGFLCGFSAQTVYDQWFITLFNIVYTSLPVLAMGLFDQDVNEQYSLRYPNLYRPGQLNQLFNKRKFFTCTLQGVYTSFILFFIPYGAFMPAVRDDGAQISDQQAFAVTIATSLVIVVSVQIGLDTNYWTAVNHFFIWGSLAVYFAILFAMNSNGIFTIFPNQFPFIGSARNSLNQKIVWLVILLNTVVCIMPMLAVRFIKTDLYPTHTDKVRL--LQQATRRQRPQEQNLRRVRR-TSSRRSAYAFSHQQGYGELITSGKNMKV----------PTSSTSTYPLSSPSRAPGEKGTTSANSRPSEHKQEVTVEDLEAR-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGD4-1", "uniprot_id": "Q9VGD4_DROME", "id": "Q9VGD4-1", "name": "Phospholipid-transporting ATPase", "aln": "MIGGRRCSEAARRLRRRPDTLELSVLGGQPIETELQEDNERTPTKGAGNVDEPGIEAPEASCSAPSKRTRWFQFARSSKNRRKRLHCNEDEDVKQPERRNSDLEGSPRACLAQPEGMNIGSSTQTIATPLMIGDSFYSLAPGGGNPPPNKSDDQELYKQRDPSVTSESKSVPSLRRLSQIRRRRSSYYFSENERRIRANDKEFNAQFKYHNNYIKTSKYSLFTFLPFNLLEQFQRLANFYFLCLLVLQLIPAISSLTPVTTAIPLIGVLTLTAVKDAYDDIQRHISDSQVNNRKSKTLRNGKLVEAKWSEVQVGDVIRLDNNQFVAADTLLLSTSEPNGLCFIETAELDGETNLKAKQCLTETIELGDRHDSLWNFNGEIICERPNNLLNKFDGTLIWRGQRFALDNEKILLRGCVLRNTQWCYGVVVFAGVDTKLMQNSGKTQFKSTGVDRLLNFIIIGIVLFLVSICALFAIGCAIWEGLIGQHFQLYLPWEHIIPKDYIPTGATVIGLLVFFSYAIVLNTVVPISLYVSVEVIRFVQSFLINWDEEMYYPTTNTYAKARTTTLNEELGQIQYIFSDKTGTLTQNIMTFNKCSINGRSYGDVIDLRTGELVEITEQQTIFQNSNTNNRPSPLSGAIVAPPAAPPPIILVHKAEVHAKKTSMVVTSSGEAQVLPDRPRSDIERSAPPMDASEKRPGLKHVRYSAPSRSQDADAGRLSPRLDGSGGLSPPVGNEERRISGGFKRSGAGCMQRQLSRTSSCDKVKILHDSQQTETHNMHHSSHNRKRLVKIRFKKAPSTATLGVVISQLEHHLDEEPQSTSTLSTTKHHHHRSKAFATNWSSSPHRVHALQSVDFSANPHHESDFRWYDRTLLDAVRSDEEHSHVFFRLLALCHTVMAET-VDGKLEYQAQSPDEAALVSAARNFGFVFRTRTPNSITIEVMGQTEEYELLNILDFNNVRKRMSVILRRGDS-MVLYCKGADNVIYDRLHGGQEDLKARTQDHLNKFAGEGLRTLALAERRLTEQYYNDWRSRQQEAALSMDSREQKLNAIYEEIESEMQLVGVTAIEDKLQDGVPKSIANLQNAGIKIWVLTGDKQETAINIGYSCQLLTDELADVFIVDGNSVEEVEKQLRQFKESIKIYNRFRPGGFDPFDRLNSDSNMDPLSVTMTQTSAFMQETNLPPTPPPPPAISVVTFRWDEKNKDNKGGPDSAECNNLFGDEKGSEDGGTASIVVDENTGFALVVNGHSLVHCLSPELENKFLDIASQCKAVICCRVTPLQKALVVELIKRAKNAVTLAIGDGANDVSMIKAAHIGVGISGQEGLQAVLSSDYSIAQFRYLERLLLVHGRWSYYRMCKFLRYFFYKNFAFTLCHCWYSLFCGFSAQTVFDPMFISVYNLFYTSLPVLALGVFEQDVSDKNSLEFPRLYTPGLKSELFNIREFIYSVLHGAFTSLVLFLIPYGVYKDGVSANGFVVSDHMTLGAVVATILIVDNTAQISLYTSYWTVVNHVTIWGSLVWYFVLDYFYN-------YVIGGPYVGSLTQAMKDLTFWVTMLITVMALVAPVLAYKFYLLDVHPSLSDKIRQKSLKKIHSRASSDVRRTASSRRGRRSVRSGYAFAHQEGFGRLITSGKIMHKLPQDFAFPLGLGTKKTQVLHNNLNSADGPNSKGNNVTGHHMVNNNTNMRHNQNQNHSSMADITADGRGNGGDDGRGSGGSDDMSPRAPCQDLDTINL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. * ** ::***:::* :*.* :* *:*:**.::****:**:**:**.** *** **:***** ****: .** :**: *:::****** ** ** **.***.*:*:.* :.** : ** :*:***:*:*:******** ****:*** ***::************.::.*. * :** * *:* : ** *** *::* * * *:..:..*.*:*::****:****.**:*:*:*** :******.*:*:** *.:*:*:* ::: *. **:.: ::*:* :* * *..* *.. . . *:*.*:** *:***:***********:*: :*::****..***. . * ************:::**************.*::*****: *. : . :**:: .*** :. : :::.* *::::. : : *:**********.* *:* **.*****.***:*******:*::***::**: :* *:** :***** *******:*. .. : **.****.:::::*. .:* * *.:**.:**********:* : * :. :. * . * : .*:::: .:***** : *:*.**:*****:** :::: * *.****:***** ***:****:*::* * : :*:: *:. **.::** *: : . . .. : .: : : . :**::*****.*.*..:::: ::::*. **:*:********** ****:*: :.*****************:****:*******:****:***::******:***********.***:** *********** * *:.: ********:* **:::*:.********:*:*:**:.:: *: *.** ** . *** *.*: .. :* :**: **:****.: . :* ::* ::...:** *:: : **.* *.*** :**. ****:. ** : : : *::*. .::.: .*:.:*:..:. : *::. :* ::*: :*::* :: : . . ** * **.***:**:*:*.****** *: : .. . . . . .: ..: ", "identical_positions": 547, "similar_positions": 353, "identity": "31.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121119-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DAS2-1", "uniprot_id": "CMI2C_MOUSE", "id": "Q9DAS2-1", "name": "Ciliary microtubule inner protein 2C", "aln": "------MAFRSAGTLMTEFNAAFVPPALMPGYKGHVPGVASSFGSSYGNTTFKYFQDLRNTGLEKSYALLS-GGCFPTIFSPNSPLVLTDNSQNWDRWLHQPTYSRSNQDNGRTTELTNFYKTVQQQRKYYQDKTGILSRVPYFVLPVKEPDRYPLPTDLPPLSEKSKWNLLRLSPDYKRTYQTFPSGKRVSSQERQRRDLYFEFRA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NJV1-1", "uniprot_id": "CMI2C_HUMAN", "id": "A6NJV1-1", "name": "Ciliary microtubule inner protein 2C", "aln": "------MASRSAGTLLTEFNAAYVPPGLMPGYQGHVPTVAFSFGAPYGTTTLKYFQDHRNRAMEKSHTPFSQGGHFPTIFSTNPNLLLMERASTRDRWLHKPSYTRFNLDSHRSTELTNFYQMVQQHRKYYQDKTGTVPRVPYFAMPVREPERYPLPTVLPPLCPKKKWHLLRLAPENLKTYQTFPSGKRVSPQERKKRDCYFEFRA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FGC3-1", "uniprot_id": "E7FGC3_DANRE", "id": "E7FGC3-1", "name": "Ciliary microtubule inner protein 2C", "aln": "MLIYSAMTFRGNGTLITHNNAAYIPTSLMPGYCGHIPTTKLMYGETFGNSSLKYFQNTRSAMMASSKSPYNKAGVFLS-------------SQTQDSVLILPYWVRYNTDFRKQKEIKDFSMLSQKHRENYKDKTGTVQPVNYFAVTEKKPAGTT----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *. ***:*. ***::*..***** **:* . :* .:*.:::****: *. : .* : . .* * : :.. * * * : * * * : .*:.:* *::*: *:**** : * **.:. ::* . ", "identical_positions": 47, "similar_positions": 45, "identity": "22.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121120-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QXW9-1", "uniprot_id": "LAT2_MOUSE", "id": "Q9QXW9-1", "name": "Large neutral amino acids transporter small subunit 2", "aln": "MEKGARQRNNTAKNHPGS-DTSPEAEASSGGGGVALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAGSVGLALIVWIVTGIITAVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEFFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANIAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCLSTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKVSLLFPIIYLLFWAFLLIFSLWSEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFNDFIKSLTLVSQKMCVVVYPQ-EGNSGAEETT-DDLEEQHKPIFKPTPVKDPDSEEQP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHI5-1", "uniprot_id": "LAT2_HUMAN", "id": "Q9UHI5-1", "name": "Large neutral amino acids transporter small subunit 2", "aln": "MEEGARHRNNTEKKHPGGGESDASPEAGSGGGGVALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENAGSVGLALIVWIVTGFITVVGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPESGLRLLAAICLLLLTWVNCSSVRWATRVQDIFTAGKLLALALIIIMGIVQICKGEYFWLEPKNAFENFQEPDIGLVALAFLQGSFAYGGWNFLNYVTEELVDPYKNLPRAIFISIPLVTFVYVFANVAYVTAMSPQELLASNAVAVTFGEKLLGVMAWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSVLAMIHVKRCTPIPALLFTCISTLLMLVTSDMYTLINYVGFINYLFYGVTVAGQIVLRWKKPDIPRPIKINLLFPIIYLLFWAFLLVFSLWSEPVVCGIGLAIMLTGVPVYFLGVYWQHKPKCFSDFIELLTLVSQKMCVVVYPEVERGSGTEEAN-EDMEEQQQPMYQPTPTKDKDVAGQPQP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXU6-1", "uniprot_id": "E7EXU6_DANRE", "id": "E7EXU6-1", "name": "Large neutral amino acids transporter small subunit 2", "aln": "MTDGPRQRGSAAPSTASE-DGGAADTGNTAGQSVALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENASSVGLALIVWILTGIITAIGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQPLFPTCFPPENGLRILAAICLLLLTWVNCSSVRWATRVQDVFTAGKLLALILIIIMGIVQICKGEYYWLEPANAFEPFQDYDVGLIALAFLQGSFAYGGWNFLNYVTEELVDPYVNLPRAIFISIPLVTFVYVFANIAYVTAMSPQELLASNAVAVTFGEKLLGVMSWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSLLAMIHVKRCTPIPALLFTCISTLLMLCTSDMYTLINYVGFINYLFYGVTVAGQIVLRIKQPDMHRPIKISLVWPVIYLLFWAFLLIFSLYSEPVVCGIGLAIMLTGVPVYFLGVYWDNKPQCFNTFVDKMTYLGQKFCVVVYPMEEVKKTDESAEGIELKEQTAPLSAEGEETPKSADC----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .*.*:*..: . .. : .. ..:.* .************************************.**********:**:**.:**********************************************************************.***:*************************:********* **************::**** **** **: *:**:**************************** *********************:*****************************:*************************************:*******************:****** ****************************** *:**: ****:.*::*:**********:***:**************************::**:**. *:. :* :.**:****** * . *.: :::** *: . . ", "identical_positions": 426, "similar_positions": 62, "identity": "79.48%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121120-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DCP2-1", "uniprot_id": "S38A3_MOUSE", "id": "Q9DCP2-1", "name": "Sodium-coupled neutral amino acid transporter 3", "aln": "MEIPRQTEMVELVPNGK---HLEGLLPVGVPTTDTQRTED-TQHCGEGKGFLQKSPSKEPHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGIVGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEKPASVWYMDGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFQVPCPLAHNLANATGNFSHMVVAEEKAQLQGEPDTAAEAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKRKMQHISNLSIAVMYVMYFLAALFGYLTFYDGVESELLHTYSKVDPFDVLILCVRVAVLIAVTLTVPIVLFPVRRAIQQMLFQNQEFSWLRHVLIATGLLTCINLLVIFAPNILGIFGIIGATSAPCLIFIFPAIFYFRIMPTDKEPARSTPKILALCFAAVGFLLMTMSLSFIIIDWVSGTSQHGGNH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99624-1", "uniprot_id": "S38A3_HUMAN", "id": "Q99624-1", "name": "Sodium-coupled neutral amino acid transporter 3", "aln": "MEAPLQTEMVELVPNGK---HSEGLLPVITPMAGNQRVEDPARSCMEGKSFLQKSPSKEPHFTDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMANTGIILFLFLLTAVALLSSYSIHLLLKSSGVVGIRAYEQLGYRAFGTPGKLAAALAITLQNIGAMSSYLYIIKSELPLVIQTFLNLEEKTSDWYMNGNYLVILVSVTIILPLALMRQLGYLGYSSGFSLSCMVFFLIAVIYKKFHVPCPLPPNFNNTTGNFSHVEIVKEKVQLQVEP--EASAFCTPSYFTLNSQTAYTIPIMAFAFVCHPEVLPIYTELKDPSKKKMQHISNLSIAVMYIMYFLAALFGYLTFYNGVESELLHTYSKVDPFDVLILCVRVAVLTAVTLTVPIVLFPVRRAIQQMLFPNQEFSWLRHVLIAVGLLTCINLLVIFAPNILGIFGVIGATSAPFLIFIFPAIFYFRIMPTEKEPARSTPKILALCFAMLGFLLMTMSLSFIIIDWASGTSRHGGNH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ATR8-1", "uniprot_id": "A0A8M3ATR8_DANRE", "id": "A0A8M3ATR8-1", "name": "", "aln": "-MEPARSEMS-ILPNGKGHDLGEEMCVPMKTMMEEEQFDDPDSTLAENIEFLPNSESKKPRFTDFDGKTSFGMSVFNLGNAIMGSGILGLAYAMANTGILLFLFLLTAVAGLSCYSIHLLLKSSGVVGIRSYEQLGFRAFGMTGKMAAAIAITLQNIGAMSSYLYIVKSEFPLVLQAFLRTDTTSGEWYLNGNYLVVLVSISIILPLALMKQLGYLGYSSGFSLSCMVFFLSAVIYKKFQILCPFEEFSANSTLTHAHSNITVDHAYHNSHV-MEDDSHCHPQMFTVNSQTAYTIPILAFAFVCHPEVLPIYTELRNPTQKKMQHVSNISILIMYTMYFLAALFGYLTFYTNVEPELLHTYSRIDPYDTLILCVRLAVLTAVTLTVPIVLFPVRRAIQEMAFPNKSFNWIRHIAIAVVLLTLINMLVIFAPNILGIFGIIGATSAPCLIFIFPAVFYIRIVPKDKEPMRSTPKIFAACFAGLGVLFMIMSLSFIIIDWTTGSGSALGGH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::** ::**** * : . :: :* *. ** :* **:*:****:************.********************:********** **.***********:****:*****:**** .**:***:****************:***:***:*:**. : :. **::*****:***::********:******************** *******:: **: *:* ..:* :. ::. : . .:.* *. **:**********:*****************::*:::****:**:** :** ************** .**.*******::**:*.******:*** ******************:* * *:.*.*:**: **. *** **:*************:******* *******:**:**:*.:*** ******:* *** :*.*:* **********.:*:. *.*", "identical_positions": 338, "similar_positions": 95, "identity": "66.4%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121120-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DBK7-1", "uniprot_id": "UBA7_MOUSE", "id": "Q9DBK7-1", "name": "Ubiquitin-like modifier-activating enzyme 7", "aln": "-------------MDEELYSRQLYVLGLPAMQRIQEAKVLLCGLQGLGAEVAKNLVLTGVGSLTLHDPHPTCWADLAAQCFLSEESLGRNRAEASQAQLAQLNEAVQISVHSGDITEDLLQGFQVVVLTDSK-LEDQLKVGPLCHKHGVRFLMAETRGLVGRLFCDFGEDFTVLDPTEVEPMTAAIQDISQGFPGIVTLRGDTKRHSFHDGDLVIFSDIEGMVELNSCSPQSVRVQKDGSLEIGDTTTFSRYLRGGVVTEVKRPKTVRHKPLDIALLQPH-----VVAQNTQEVQRAHCLHQAFHVLHKFQQLHG-RLPKPWDPDDAETVVELAQDLEPLKGTEEE----SLDEALLRTIALSSAGTLSPMAAIMGGVAAQEVLKAISRKFMPLDQWLYFDALECLPEDETLLPSPEDCQPRNCRYDGQIAVFGTDLQEKLSDQHYLLVGAGAIGCEMLKVFALVGLGVRANGGVTVADMDYIERSNLSRQFLFRPKDVRRPKAEVAAAAAHRLNPDLR--ATPYTCPLDPTTEDIYDDSFFSRVNGVVAALDSFQAR--------------------------HYVAARCTHYLKPLLEAGTQGTWGSASVFVPYVTEAYRGPASDAASEDAPYPVCTLRHIPSSMEHSVQWAQDQFEGLFRLSTETINCYQQT---CTS-LSATDRTETLALLQQVMGVLRTR-PQTWQDCVVWALGHWQLCFHD------------KVLEGGTQFSSGSNKCPHPLQFDPNHDMHFLYVLAAANLYARMHGLPGSQ-----SQPALRELLTR--LLESDSRPQNLFS-----------AEHGQE--QLKELQETLDDWRKGPP---LKPVLFVKDDDSNFHVDFVVAATDLRCQNYGILPVNHARIKQIVGRIIPAIATSTAVVAGLLGLELYKVVSGLRSHGTFRHSYLHLAENHFIRSAPSAPAVQSFRDLKWT-CWDRLKVPAV---QPERTLKSLLAHLQEEHGLKVEMLLHHQALLYSSGWSSEKQAQHLCLRVTELVQHVTGWKPKPGLKVLVFELSCE-GEEEE-MAFPPLHYEL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G652-1", "uniprot_id": "A0A8I6G652_RAT", "id": "A0A8I6G652-1", "name": "", "aln": "-------------MDEELYSRQLYVLGLPAMQRIREAKVLLCGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWADLAAQFFLSEESLGRSRAEASQPQLAQLNEAVQISVHRGDITEDLVRGFQVVVLTDSK-LEDQLNMGALCHKNRVYFLMAETRGLVGRLFCDFGEDFTVVDPTEVEPTSAAIQDISQGSPGIVTLRGGSKRPSFYDGDLVMFSDIEGMVELNSHSPQPVRVQKDGSLEIGDTTTFSRYLRGGVVTEVKRPKTVKHKPLDIALLQPC-----MVVQNTQEIQRAHCLHQTFHALHKFQQLHG-RLPKPWDPDDAETVVWLAQDLEPLKGAKEE----SLDEALLRTIALSSAGSLSPMAAILGGVAAQEVLKAVSGKFMPLDQWLYFDALECLPEDETLLPSPEDCHPRNCRYDGQIAVFGTGFQEKLSYKHYLLVGAGAIGCEMLKGFALVGLGVRDNGGVTIADMDHVERSNLSRQFLFRPKDTGRPKAEVAAEAAHRLNPDLQ--VTSHTCPLDPTTEDIYDDDFFSRVDGVVAALDSFQARESLTESQVPCPRLWQPHPIPSTLLPGHYVAARCTHYLKPLLEAGTQGTRGSASVFVPYVTEVYKGPTS---AEEAPYPVCTLRHFPSTVEHSLQWAQDEFEGLFRLSAETINDYQQT---CTSSLLGTDGTGILALLQQVMGVLRTR-PQTWQDCVVWALGHWQLCFRDNIVELLRKFPSDKVLEDGTLFWSGSKKCPHPLQFDPNQDTHFLYVLAAANLYARMHGLPGSQ-----SQTALRELLTLTLLQEPDSMPQNLFS-----------AEFGQE--QLKELQETLDDWNKGPP---LKPVLFGKDDSSNFHEDFVVAATDLRCQNYGILPVNRARIKQTIGRIIPAIATSTAVVAGLLGLELYKVVSGPRPLGTFRHSYLHLAENHFIRSAPSAPAMQSFHHLEWT-CWHRLTVPAG---QPERTLESLLAHLQEEHGLTVRMLLHDQALLYSSGWPFEKQAQHLGLRTSS-----AGDRP---------ETQAW-AESSG-V----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41226-1", "uniprot_id": "UBA7_HUMAN", "id": "P41226-1", "name": "Ubiquitin-like modifier-activating enzyme 7", "aln": "----MDALDASKLLDEELYSRQLYVLGSPAMQRIQGARVLVSGLQGLGAEVAKNLVLMGVGSLTLHDPHPTCWSDLAAQFLLSEQDLERSRAEASQELLAQLNRAVQVVVHTGDITEDLLLDFQVVVLTAAK-LEEQLKVGTLCHKHGVCFLAADTRGLVGQLFCDFGEDFTVQDPTEAEPLTAAIQHISQGSPGILTLRKGANTHYFRDGDLVTFSGIEGMVELNDCDPRSIHVREDGSLEIGDTTTFSRYLRGGAITEVKRPKTVRHKSLDTALLQPH-----VVAQSSQEVHHAHCLHQAFCALHKFQHLHG-RPPQPWDPVDAETVVGLARDLEPLKRTEEEPLEEPLDEALVRTVALSSAGVLSPMVAMLGAVAAQEVLKAISRKFMPLDQWLYFDALDCLPEDGELLPSPEDCALRGSRYDGQIAVFGAGFQEKLRRQHYLLVGAGAIGCELLKVFALVGLGAGNSGGLTVVDMDHIERSNLSRQFLFRSQDVGRPKAEVAAAAARGLNPDLQ--VIPLTYPLDPTTEHIYGDNFFSRVDGVAAALDSFQAR--------------------------RYVAARCTHYLKPLLEAGTSGTWGSATVFMPHVTEAYRAPASAAASEDAPYPVCTVRYFPSTAEHTLQWARHEFEELFRLSAETINHHQQA---HTS-LADMDEPQTLTLLKPVLGVLRVR-PQNWQDCVAWALGHWKLCFHYGIKQLLRHFPPNKVLEDGTPFWSGPKQCPQPLEFDTNQDTHLLYVLAAANLYAQMHGLPGSQ-----DWTALRELLKLLPQPDPQQMAPIFASNLEL---ASASAEFGPE--QQKELNKALEVWSVGPP---LKPLMFEKDDDSNFHVDFVVAAASLRCQNYGIPPVNRAQSKRIVGQIIPAIATTTAAVAGLLGLELYKVVSGPRPRSAFRHSYLHLAENYLIRYMPFAPAIQTFHHLKWT-SWDRLKVPAG---QPERTLESLLAHLQEQHGLRVRILLHGSALLYAAGWSPEKQAQHLPLRVTELVQQLTGQAPAPGQRVLVLELSCE-GDDED-TAFPPLHYEL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P22515-1", "uniprot_id": "UBA1_YEAST", "id": "P22515-1", "name": "Ubiquitin-activating enzyme E1 1", "aln": "MSSNNSGLSAAGEIDESLYSRQLYVLGKEAMLKMQTSNVLILGLKGLGVEIAKNVVLAGVKSMTVFDPEPVQLADLSTQFFLTEKDIGQKRGDVTRAKLAELNAYVPVNVLDSLDDVTQLSQFQVVVATDTVSLEDKVKINEFCHSSGIRFISSETRGLFGNTFVDLGDEFTVLDPTGEEPRTGMVSDIEPD--GTVTMLDD-NRHGLEDGNFVRFSEVEGLDKLNDGTLFKVEVLGPFAFRIGSVKEYGEYKKGGIFTEVKVPRKISFKSLKQQLSNPE-----FVFSDFAKFDRAAQLHLGFQALHQFAVRHNGELPRTMNDEDANELIKLVTDLSVQQPEVLG-EGVDVNEDLIKELSYQARGDIPGVVAFFGGLVAQEVLKACSGKFTPLKQFMYFDSLESLPDPKNFPRNEKTTQPVNSRYDNQIAVFGLDFQKKIANSKVFLVGSGAIGCEMLKNWALLGLGSGSDGYIVVTDNDSIEKSNLNRQFLFRPKDVGKNKSEVAAEAVCAMNPDLKGKINAKIDKVGPETEEIFNDSFWESLDFVTNALDNVDAR--------------------------TYVDRRCVFYRKPLLESGTLGTKGNTQVIIPRLTESYSSSRD---PPEKSIPLCTLRSFPNKIDHTIAWAKSLFQGYFTDSAENVNMYLTQPNFVEQTLKQSGDVKG--VLESISDSLSSK-PHNFEDCIKWARLEFEKKFNHDIKQLLFNFPKDAKTSNGEPFWSGAKRAPTPLEFDIYNNDHFHFVVAGASLRAYNYGIKSDDSNSKPNVDEYKSVIDHMIIPEFTPNANLKIQVNDDDPDPNANAANGSD--EIDQLVSSLPDPSTLAG-FKLEPVDFEKDDDTNHHIEFITACSNCRAQNYFIETADRQKTKFIAGRIIPAIATTTSLVTGLVNLELYKLIDNKTDIEQYKNGFVNLALPFFGFSEPIASPKGEYNNKKYDKIWDRFDIKG------DIKLSDLIEHFEKDEGLEITMLSYGVSLLYASFFPPKKLKERLNLPITQLVKLVTKKDIPAHVSTMILEICADDKEGED-VEVPFITIHL-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0ACD6B740-1", "uniprot_id": "A0ACD6B740_DANRE", "id": "A0ACD6B740-1", "name": "E1 ubiquitin-activating enzyme", "aln": "--------MAQGDIDEGLYSRQLYVIGHDAMRRMGKADVLIAGMRGLGVEIAKNVILAGVRTVTIQDEGVVEWRDLSSQFYLKEADLGQNRALCSEKQLSSLNAYVKVSASTNKLDENFLSKFQVVVLTSSP-LDEQLRVGAFCHSNNIKFIVADTRGLCGQLFCDFGESFEVIDTNGDPPVSAMISHISKENPGVVNCTDE-ESHEFTDGMFVTFSEVQGMTELNNYGPVEIKVKDSYSFSICDTSNFSDYVKCGVATEVKQPEILSFKPLNVALDEALRDPGLVEMTDYGKTKRHLSLHLAFQALHKFTQKYS-RTPHPRSQADAEVLLTITKELCTEA------KFDKLDEDAVRNLSLVASGDLAPVNAFIGGLAAQEVVKACSGKFTPLRQWLYFDALECLPQEEGGVLSEDACAPRDSRYDGQIAVFGSDFQNKLKKQKYFLVGAGAIGCELLKNFALIGLGAGEGGSITVTDMDSIERSNLNRQFLFRSQDIGRPKSEAAAEAVKEMNPFMN--IIAQQNRVCAETEEVYTHSFYTGLDGVAAALDNVDAR--------------------------VYLDQCCVRNKKPMLEGGTLGSKGHTMVVVPRLTESYGRSSS---GGQKAIPICTLKNFPHRIEHTLQWARDHFEGLFKQTAQNVNNFLSDPGFVDRTVAR-GDVEAVEMLEGVYRSLSDDWPENWKDCISWARRQWETLYNNHIRQLLHCFPPDQLTSSGLPFWMGAKRCPHALTFDTNNATHMDFIIAAANLYAQIFGITGSR-----NRADIQTVLQGVKVPEFTPKSSVKIAVTDQQLNEENEERKEEDKVKLGMLKEQLSKLQLRDRSFRMHPQDFEKDDDSNFHMDYIVAASNLRAENYDIPTADRHKSKLIAGRIIPAIATTTAAIAGLMCLELYKLVQGHSKITSYRNAYINLATQYFVFSQPCPAPTFTVAGQRYS-LWDDFPVQGCREGQEEMTLEELLKHIEEKHKLKISGLYYGPAVLYSDLS---NHSDRMKLSISDLVRLATKHEVADHQ--QMLEIIPSFEEDEDCLTVPPIRYLLR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** ********:* ** :: : **: *::***.*:***::* ** ::*: * . **::* *.* .: :.*. :. *:.** * : . . : ***** * : *::::.:. :**. : *: ::**** *. * *:*:.* * *.. * :. :..*. * :. : : ** :* ** ::*: :**. :.* :: * ... :. * : * **** *. : .*.*. * :. . . : .: ** * .**:* :. . *:. . **: :: :. :* ::* :: :: : * :. : *::*.:.****:** * ** ** *::***:*:.**: . . ..***.****** .:*:*: .: :***:******:** :**:*** .* :.:.* * :*:***.******.:* : *:*.** *. :** :. . : . **.:: ..*: :: *. ***..:** *: *. **:**.** *: * : *.:* :** * . . : . *:**:: :* :*:: **: *: * :::.:* . : . :*: : * *..::**: ** .:: :. ..* * *.::.* .* ** : *: :::*.*.* * .*: .. . : :: : . : : * . * :.* * ***.:*.* :::.*.:. *.:** * ..:: : * *:*******:*: ::**: *****::.. :::.:::** .: * ... .: *. : : . : .*..*: *:::.. * : * : ::**: : ::: * :. : * : . ", "identical_positions": 260, "similar_positions": 315, "identity": "24.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121127-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0MZ67-1", "uniprot_id": "SHOT1_RAT", "id": "A0MZ67-1", "name": "Shootin-1", "aln": "MNSSDEEKQLQLITSLKEQAIGEYEDLRAENQKTKETCDKIRQERDEAVKKLEEFQKISHMVIEEVNFMQNHLEIEKTCRESAEALATKLNKENKTLKRISMLYMAKLGPDVITEEINIDDDDPGTDTDAAAETCVSVQCQKQIKELRDQIVSVQEEKKVLAIELESLKSKLGEVMEEVNKVKQEKAVLNSEVLEQRKVLEKCNRVSVLAVEEYEELQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLLQSSLPDQQLLKALDENAKLIQQLEEERIQHQQKVKELEERLENEALHKEIHNLRQQLELLEDDKRELEQKYQSSEEKARNLKHSVDELQKRVNQSEN---SVPPPPPPPPPLPPPPP------NPIRSLMSMIRKRSHPSGGSTKKEKATQPETAEEVTDLKRQAVEEMMDRIKKGVHLRPVNQTA-RPKAKPDSLKGSESAVDELKGILGTLNKSTSSRSLKSLGPENSE-TELERILRRRKLTAEADSSSPTGILATSESKSMPVLGSVSSVTKSALNKKTLEAEFNNPCPLTPEPGEGPRKLEGCTNSKVTFQPPSKGGYRRKCVGSENQSEPVVVLDPVSTHEPQTKDQAAEKDPTQCKEEERGETQPEFKEDSSGGKTGETDSSNC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K2Q9-1", "uniprot_id": "SHOT1_MOUSE", "id": "Q8K2Q9-1", "name": "Shootin-1", "aln": "MNSSDEEKQLQLITSLKEQAIGEYEDLRAENQKTKEKCDKIRQERDEAVKKLEEFQKISHMVIEEVNFMQNHLEIEKTCRESAEALATKLNKENKTLKRISMLYMAKLGPDVITEEINIDDDDPATDTDAAAETCVSVQCQKQIKELRDQIVSVQEEKKVLAIELENLKSKLGEVMEEVNKVKQEKAVLNSEVLEQRKVLEKCNRVSMLAVEEYEELQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLLQSSLPDQQLLKALDENAKLIQQLEEERIQHQKKVKELEERLENEALHKEIHNLRQQLELLEDDKRELEQKYQSSEEKARNLKHSVDELQKRVNQSEN---SVPPPPPPPPPLPPPPP------NPIRSLMSMIRKRSHPSGNSAKKEKTTQPETAEEVTDLKRQAVEEMMDRIKKGVHLRPVNQTA-RPKAKPDSLKGSESAVDELKGILGTLNKSTSSRSLKSLGPENSE-TELERILRRRKLTAEADSSSPTGILATSESKSMPVLGSVSSVTKSALNKKTLEAEFNNPCPLTPEPGEGPRKLEGCTNPKVTFQPPSKGGYRRKCVGSENQAEPVVVLDPVSTHEPQTKDQAAEKDPTQFEEE-GGETQPEYKEDS-GGKTGETDSSNC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0MZ66-1", "uniprot_id": "SHOT1_HUMAN", "id": "A0MZ66-1", "name": "Shootin-1", "aln": "MNSSDEEKQLQLITSLKEQAIGEYEDLRAENQKTKEKCDKIRQERDEAVKKLEEFQKISHMVIEEVNFMQNHLEIEKTCRESAEALATKLNKENKTLKRISMLYMAKLGPDVITEEINIDDEDSTTDTDGAAETCVSVQCQKQIKELRDQIVSVQEEKKILAIELENLKSKLVEVIEEVNKVKQEKTVLNSEVLEQRKVLEKCNRVSMLAVEEYEEMQVNLELEKDLRKKAESFAQEMFIEQNKLKRQSHLLLQSSIPDQQLLKALDENAKLTQQLEEERIQHQQKVKELEEQLENETLHKEIHNLKQQLELLEEDKKELELKYQNSEEKARNLKHSVDELQKRVNQSEN---SVPPPPPPPPPLPPPPP------NPIRSLMSMIRKRSHPSGSGAKKEKATQPETTEEVTDLKRQAVEEMMDRIKKGVHLRPVNQTA-RPKTKPESSKGCESAVDELKGILGTLNKSTSSRSLKSLDPENSE-TELERILRRRKVTAEADSSSPTGILATSESKSMPVLGSVSSVTKTALNKKTLEAEFNSPSPPTPEPGEGPRKLEGCTSSKVTFQPPSSIGCRKKYIDGEKQAEPVVVLDPVSTHEPQTKDQVAEKDPTQHKED-EGEIQPENKEDS-IENVRETDSSNC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P0R8-1", "uniprot_id": "SHOT1_DANRE", "id": "Q6P0R8-1", "name": "Shootin-1", "aln": "MASKGKKNKVRTNSDLSNQVLLQYESLQKEHEKIKKECKKLQEERDEALRKLNEFESVSHRVIEEVNSIQENLEIEKTCRESVEALASKLNRQNLSLKRKSMLYMSRLAADVV-AEISIDDEDDEDAHEEEAGVCSSSHCHIVITELRDKLEEILATKKQLMIDLETTREQLSKTRQELLKEKHDNTVLIAETFQQKKLLGKYNRVSQYALDEFESLQEDLKLERDLRSEAEKFAHEMLIEQKKLKRQSQVLVQSISVGEALQKALAEISTLTHTLEKQRLEHQQQVKGLEEQVNSSEVKKQLTALQRQTDLLEEERKEWQHKHTKAETEAKDLRFTVEELKKKLQQVSNPPTAAPAPPPPPPPPPPPPPPSSSSSNPLSSLLSILRKKKDVSTEIALVEKDSSEKSPEK--DVRQQAVDEMMLRIKKGVQLRPVSQTTNRVRPGPKEPTASNSAIQELQGILNTVKRPGPSSSPGPRPPSPSEKSELEKALQRRREAVKSAKNN------TNPS-------SVVDLTQIKQTRS--------------EPGQN-------TGDQETLR----------------HTTTTICTEQLS-----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCH2-1", "uniprot_id": "Q9VCH2_DROME", "id": "Q9VCH2-1", "name": "", "aln": "---------MERRGRIPVAKFRTQEAKTRSRSRVREPDYNEQDPEHDMFTLLEDNIALR----EENKALKLEIETHKTTQEEQQAQHEKMCATLESLQQQ----QTNFETQIKELSAKFNKALNERNALDKLHKMKVDQIHNLTSELEHIREKQQDQAPPIAPRSVLGSVELKRKLFKILQSGSADSADSIGTQELDSLVDANSEGVPITSGLVERLANEFLTLKNFTNSVELQLYEANEKMAELLEQQHAMEEENEALRTENSNLTKVAKLLTENMKESVETSQKMEAALIKLK----QRNDELTAKTRDLTDGQPGSRTSTSSSVLNEQVEFEQIQDQVQQQAREHNER------------------------IVEMQNLMDAAIAKTTNDELKKLQLKLEILEEQLREAVTRADRAEEQLAHYQQSEQKSLVAPTP--PPPPPPPPPPMPGKLFPPGGLVAAGGGSLSDHIAGHSLRKGSG----DKIIENVKHQVQAEAATGLDALMREFK--------SGGVTLRRRNRR--------------KTGTSEALKEMFQVLEISQK---------------QNRNSKICVDLHSSRGVDV-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : : * ...: :: : :: ..: . *:: : ** : :: .:* .** :*. :* *: :*:: :.: .:: . .::. : : .**.. . : :* . :: : .:. . : .:: .. : * : :: ::: ...* * : :* .*.: : :. . . * : :.* :: :: .:::: ::: ::: : :* : : . . . : ::. :::::: .: .: : .*:. :. . * : . : : .:* : : ::. : * *. . * . : *:: : . .. . * :: :.. : .:: . . . .:* .: :.* . : : : : . : : * ", "identical_positions": 33, "similar_positions": 181, "identity": "5.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121127-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15385-1", "uniprot_id": "KCNA4_RAT", "id": "P15385-1", "name": "Potassium voltage-gated channel subfamily A member 4", "aln": "MEVAMVSAESSGCNSHMPYGYA-AQARARERERLAHSRAAAAAAVAAATAAVEGTGGSGGGPHHHHQTRGAYSSHD----------PQGSRGSREEEATRT------------EKKKK---LHHRQSSFPHCSDLMPS-----GSEEKILRELSEEEEDEEEEEEEEEE-GRFYYSEEDHGDGCSYTDLLPQDDGGGGGYSSVR-YSDCCERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLIMALSAGGHSRLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQ----------GGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQT-QLTQNAVSCPYLPSNLLKKFRSSTS-SSLGDKS-EYLEMEEGVKES----------------LCGKEEKCQ---------------------------------------------------------------------GKGDDSETDKNNCSNAKAVETDV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61423-1", "uniprot_id": "KCNA4_MOUSE", "id": "Q61423-1", "name": "Potassium voltage-gated channel subfamily A member 4", "aln": "MEVAMVSAESSGCNSHMPYGYA-AQARARERERLAHSRAAAAAAVAAATAAVEGTGGSGGGPHHHHQTRGAYSSHD----------PQGSRGSRRRRRQRT------------EKKK----LHHRQSSFPHCSDLMPS-----GSEEKILRELSEEEEDEEEEEEEEEE-GRFYYSEEDHGDGCSYTDLLPQDDGGGGGYSSVR-YSDCCERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLIMALSAGGHSRLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQ----------GGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQT-QLTQNAVSCPYLPSNLLKKFRSSTS-SSLGDKS-EYLEMEEGVKES----------------LCGKEEKCQ---------------------------------------------------------------------GKGDESETDKNNCSNAKAVETDV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22459-1", "uniprot_id": "KCNA4_HUMAN", "id": "P22459-1", "name": "Potassium voltage-gated channel subfamily A member 4", "aln": "MEVAMVSAESSGCNSHMPYGYA-AQARARERERLAHSRAAAAAAVAAATAAVEGSGGSGGGSHHHHQSRGACTSHD----------PQSSRGSRRRRRQRS------------EKKK----AHYRQSSFPHCSDLMPS-----GSEEKILRELSEEEEDEEEEEEEEEE-GRFYYSEDDHGDECSYTDLLPQDEGGGG-YSSVR-YSDCCERVVINVSGLRFETQMKTLAQFPETLLGDPEKRTQYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLKRPVNVPFDIFTEEVKFYQLGEEALLKFREDEGFVREEEDRALPENEFKKQIWLLFEYPESSSPARGIAIVSVLVILISIVIFCLETLPEFRDDRDLVMALSAGGHGGLLNDTSAPHLENSGHTIFNDPFFIVETVCIVWFSFEFVVRCFACPSQALFFKNIMNIIDIVSILPYFITLGTDLAQQQ----------GGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLIFFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETENEEQT-QLTQNAVSCPYLPSNLLKKFRSSTS-SSLGDKS-EYLEMEEGVKES----------------LCAKEEKCQ---------------------------------------------------------------------GKGDDSETDKNNCSNAKAVETDV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q929-1", "uniprot_id": "F1Q929_DANRE", "id": "F1Q929-1", "name": "Potassium voltage-gated channel subfamily A member 4", "aln": "MEFAMVGADSGGCNTHLPYGYAQARARERERERERHSRAAAAAAAEAG-AVGEGGGSTGHPHNHPHQSRAASSTNANNSSAGTASRPSSSSSSQQPQQQQQQQHHEPPQQLLRERKKQRGVARWRRNRAALGGDLRQSELALLGSEEDIMIEEEEEAEGEEEEEDRKSKRSSFVYNMDDEEETVSLTDRRPQS-----GYENVYNEYGCCERVVINVSGLKFETQLKTLAQFPDTLLGDPEKRSRYFDPLRNEYFFDRNRPSFDAILYFYQSGGRLKRPVNVPFDIFSEEVKFYELGDEAMLKFREDEGFVKEEE-KPLPEDEFKRQIWLLFEYPESSSPARGIAVVSVLVIVISIVIFCLETLPEFRDDKEFLIPG--------KNSTQA----DNGFTPFNDPFFIVETVCIIWFSFEIIVRFFASPSKADFFKNVMNTIDIVSILPYFITLGTDLAQQQ----------GNG----QQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELALLIFFLVIGVILFSSAVYFAEADEPTSQFTSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDNEDQAPAVEQPPPGCPYFP-DFLRKFKGSPSGSSLGDKAAEYMEMEEGVTES----------------LCGGDTQSP---------------------------------------------------------------------SRGNGTDLGGKNSSHSRTLQTDV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08510-1", "uniprot_id": "KCNAS_DROME", "id": "P08510-1", "name": "Potassium voltage-gated channel protein Shaker", "aln": "------------------------------------------------MAAVAGLYGLGEDRQHRKKQQ------------------QQQQHQKEQLEQKE------------EQKK--------------------------IAERKLQLREQQLQRNSLDGYGSLPK----LSSQDEEGGAGHGFGGGPQH------FEPIPHDHDFCERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEE-RPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVF------------NTTTNGTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQEEMQSQNFNHVTSCPYLPGTLGQHMK----KSSLSESSSDMMDLDDGVESTPGLTETHPGRSAVAPFLGAQQQQQQPVASSLSMSIDKQLQHPLQQLTQTQLYQQQQQQQQQQQNGFKQQQQQTQQQLQQQQSHTINASAAAATSGSGSSGLTMRHNNALAVSIETDV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * . * :* :: : . . .:. : *:** :*..: . .: ... : : . ::. . ** :. : . ***********:****::** ***:****** :* :*************.*********:*******:******:*:*:**:***:**::*: ********::*** :.**::* ::::**********..** :*::**:**::*************:. : : . *.. :. . :.****::**:**:**:**: ** :*.*.: * :::** ***::*:******.* :*::: . :****:****:***********************:**:******.******.***:***********.. .: * *********************.*: * ***********************************::*: : .***:* : :::: ***.:.: : :::::** .: * . : : . *. :* : : :::***", "identical_positions": 292, "similar_positions": 151, "identity": "37.15%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121127-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZNW7-1", "uniprot_id": "A0A8I5ZNW7_RAT", "id": "A0A8I5ZNW7-1", "name": "Anoctamin", "aln": "MQWGAGTGRGEGAAAGDPVTPGAESWGDPRTKAPGAEQRGAGGWAQPSSRLCRSLCWTQGVRSEHIMQDTQDSDISLEGLTREGAPADRECQRGPETIVHEAQDAGTPNSDATGAVDGEREATMRVPEKYSTLPAEDRSVHIVNICA----IEDLGYLPSEGTLLNSLSVDP-DAECKYGLYFRDGKRKVDYILVYHHKRASGSRTLARRGLQNDMVLGTRSVRQDQPLPGKGSPVDVGSPEAPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWHVLCREAEFLKLKMPTKKVYHISETRGL-LKTINSVLQKITDPIQPKVAEHR---------------------------PQTTKRLSYPFSREKQHLFDLTDRDSFFDSKTRSTIVYEILKR---TTCTKAKYSMGITSLLANGVYSAAYPLHDGDYEGDNVEFNDRKLLYEEWASYGVFYKYQPIDLVRKYFGEKVGLYFAWLGAYTQMLIPASIVGVIVFLYGCATVDENIPSMEMCDQ-RHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLRKESRNKEKRRNVPEEPTNKWKQRVRTAMAGVKLTDKVKLTWRDRFPAYFTNLVSIIFMIAVTFAIVLGVIIYRISTAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLTFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKFIRYLKLRRQSPSDREEYIKRK--QRYEVDFNLEPFAG--LTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAIRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYMYSQNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSEHKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQGKQQLLDTWMEKEKPRD-VPCNNHSPTAHPEAGDSSPVPSYEYHGGAL---------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BHY3-1", "uniprot_id": "ANO1_MOUSE", "id": "Q8BHY3-1", "name": "Anoctamin-1", "aln": "---------------------------------------------------------------------------------------------------------------------------MRVPEKYSTLPAEDRSVHIVNICA----IEDLGYLPSEGTLLNSLSVDP-DAECKYGLYFRDGKRKVDYILVYHHKRASGSRTLARRGLQNDMVLGTRSVRQDQPLPGKGSPVDAGSPEVPMDYHEDDKRFRREEYEGNLLEAGLELENDEDTKIHGVGFVKIHAPWHVLCREAEFLKLKMPTKKVYHISETRGL-LKTINSVLQKITDPIQPKVAEHR---------------------------PQTTKRLSYPFSREKQHLFDLTDRDSFFDSKTRSTIVYEILKR---TTCTKAKYSMGITSLLANGVYSAAYPLHDGDYEGDNVEFNDRKLLYEEWASYGVFYKYQPIDLVRKYFGEKVGLYFAWLGAYTQMLIPASIVGVIVFLYGCATVDENIPSMEMCDQ-RYNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLRKESRNKE--------------------------TDKVKLTWRDRFPAYFTNLVSIIFMIAVTFAIVLGVIIYRISTAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLTFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKFIRYLKLRRQSPSDREEYVKRK--QRYEVDFNLEPFAG--LTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAIRAKDIGIWYNILRGVGKLAVIINAFVISFTSDFIPRLVYLYMYSQNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSEHKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQGKQQLLDTWMEKEKPRD-VPCNNHSPTTHPEAGDGSPVPSYEYHGDAL---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XXA6-1", "uniprot_id": "ANO1_HUMAN", "id": "Q5XXA6-1", "name": "Anoctamin-1", "aln": "---------------------------------------------------------------------------------------------------------------------------MRVNEKYSTLPAEDRSVHIINICA----IEDIGYLPSEGTLLNSLSVDP-DAECKYGLYFRDGRRKVDYILVYHHKRPSGNRTLVRRVQHSDTPSGARSVKQDHPLPGKGASLDAGSGEPPMDYHEDDKRFRREEYEGNLLEAGLELERDEDTKIHGVGFVKIHAPWNVLCREAEFLKLKMPTKKMYHINETRGL-LKKINSVLQKITDPIQPKVAEHR---------------------------PQTMKRLSYPFSREKQHLFDLSDKDSFFDSKTRSTIVYEILKR---TTCTKAKYSMGITSLLANGVYAAAYPLHDGDYNGENVEFNDRKLLYEEWARYGVFYKYQPIDLVRKYFGEKIGLYFAWLGVYTQMLIPASIVGIIVFLYGCATMDENIPSMEMCDQ-RHNITMCPLCDKTCSYWKMSSACATARASHLFDNPATVFFSVFMALWAATFMEHWKRKQMRLNYRWDLTGFEEEEEAVKDHPRAEYEARVLEKSLKKESRNKEKRRHIPEESTNKWKQRVKTAMAGVKLTDKVKLTWRDRFPAYLTNLVSIIFMIAVTFAIVLGVIIYRISMAAALAMNSSPSVRSNIRVTVTATAVIINLVVIILLDEVYGCIARWLTKIEVPKTEKSFEERLIFKAFLLKFVNSYTPIFYVAFFKGRFVGRPGDYVYIFRSFRMEECAPGGCLMELCIQLSIIMLGKQLIQNNLFEIGIPKMKKLIRYLKLKQQSPPDHEECVKRK--QRYEVDYNLEPFAG--LTPEYMEMIIQFGFVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPVAVRAKDIGIWYNILRGIGKLAVIINAFVISFTSDFIPRLVYLYMYSKNGTMHGFVNHTLSSFNVSDFQNGTAPNDPLDLGYEVQICRYKDYREPPWSENKYDISKDFWAVLAARLAFVIVFQNLVMFMSDFVDWVIPDIPKDISQQIHKEKVLMVELFMREEQDKQQLLETWMEKERQKDEPPCNHHNTKACPDS-LGSPAPSHAYHGGVL---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TY29-1", "uniprot_id": "A0AB32TY29_DANRE", "id": "A0AB32TY29-1", "name": "Anoctamin", "aln": "----------------------------------------MDGFPAVTSLSSSSLCMSVDLRRREELTTMTRLESGEEQLQKAG-----------EKLLGFNSTEEQPSGQES----------MWRNEKYESVPLDVKGIDEDNSKG----TRDS--LYPHTTLLKSQQADEKPKDPKLWPYFKDGHRRIDYVLTYHIQKPQNTGKQSSKSCLGGCLCCKKRGQTNPPVPDP----ELASQEQRLDYHDDDQRLRREEFEENLREMGLEMEKEEGNKIPGVGFLKIHAPWEVLCREAEFMKLKMPTIKKYEVSHGNSI-VEKASRFMQKFTAPLQPKVGDRQ---------------------------IEHEKHLSYPFSREKQHLFDLSDRNSFFDSKTRSSIVYEILKR---TKCTRAKYIMGIISLLGNGIYTSAYPLHDGDIDDVHAEINDRKILYEEWASYSIFYKYQPIGLIRKYFGEKVGLYFAWLGVYTQMLIPAAIVGVIVFLYGCATVDDNIPSMEICDE-RNNITMCPMCDRACSYWKLVTACGTARASHLFDNAATVFFAIFMALWAAMFMEHWKRRQVRLNYLWDLTGFEDTES----HPRAEYEFHVMKKSLRKEKSPKAG---------------------------NVKLTCTDRMPAYMTIIITMIFLICVTLAIVFGVVLYRVSIMTALHMSSTPTFRSNIRATVKTTGAIINLIIIIIMDEVYGAVARWLTIMEVPKTDKSFEERLIFKTFVLKFANAFTPIVYLAFFRGRLIGRPGKYIYVMGSYRMEECAHAGCLMELCIQLCITMLGKQLIQNNLFEIGVPKIKKLLR---QRKIDPKHQEELNKTL--HRHEKDHFLGPFVG--LNPEYMEMIIQFGMVTLFVASFPLAPLFALLNNIIEIRLDAKKFVTELRRPIAVRAKDIGIWYTLLRGLSKVAVIVNAFVISFTSDFIPRLVYQYMYSPDGTLHGFVNHTLSYFNVTHFQPGTEPLEPMHLGYQVDTCRYKDYRDPPWSDTPYEFSREFWAILAARFAFVILFQNVVMLMSDFVDWLIPDIPKDISLKIHKERNLIIELFMKREQGKK-----------------YRNTMNDPSPQPLRSRPSSQA----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4JCY1-1", "uniprot_id": "A0A0B4JCY1_DROME", "id": "A0A0B4JCY1-1", "name": "Anoctamin", "aln": "--------------------------------MLNLGSAKVGALEEATSPPPFSKDESFQLLERSPHNPAISPTTTVPLEPPFTTPLAPFDMELMKRHNLHERLTGKESFWRGRDTSQRFLDQEQLSASRESLGAADKRARFAESNAPTLQLPESAEPRANGKRPTGNRTNPSNPAAPLLPMTDPDFVKGNVGGVYDDRECSCPREFYQRGEINTSLFFEDCVRS--------IDFVLAYRINAHEPTELENTEKRRVFEANLISQGLEVESSQKD---QIWFVKIHAPLEVLRRYAEILKLRMPMKESLCNLRISER-SNRLRNAAHYLTNKIPGMSVVNRSTKSVFSSLKHVFQFFLRNIYVDEEIFPKRAHRFTAIYSRDKEYLFDIR-QDCFFTTAVRSRIVEFILDRQRFPAKNQHDMAFGIERLIAEGVYSAAYPLHDGEITETG---TMRALLYKHWASVPKWYRYQPLDDIKEYFGVKIGLYFAWLGYYTYMLLLASIVGVICFLYSWFSLKNYVPVKDICQSGNTNITMCPLCD-WCNFWDLKETCNYAKVTYLIDNPSTVFFAVFMSFWATLFLELWKRYSAEITHRWDLTGFDVHEE----HPRPQYLARLEHIPPTRVDYVTN-------------------------IKEPTVPFWRMKLPATVFSFSVVLLLIALAFVALLAVVVYRMSMLAALKVGASPMTTSSAIVLATASAAFVNLCLLYILNYMYNHLAEYLTELEMWRTQTQFDDSLTLKIYLLQFVNYYASIFYIAFFKGKFVGHPGEYNKLFD-YRQEECSSGGCLTELCIQLAIIMVGKQAFN-TILEVYLPMFWRKVLAIQVGLSRLFNNTPNPDKAKDERWMRDFKLLDWGARGLFPEYLEMVLQYGFVTIFVAAFPLAPFFALLNNILEMRLDAKKLLTHHKRPVSQRVRDIGVWYRILDCIGKLSVITNGFIIAFTSDMIPRLVYRHYVNKQGTLDGYLNFTLSEFKVIDSPTLYSLAGDLSN---ITTCRYTDFRLPPSSPEKYTLSSMFYIILACRLGFVVVFENFVALVMILVRWCIPDMSVELRDQIRREVYVTNEIIIDQEAHRARFERAKRSSSVLQT--PVDQDMDAASIQEPNAKFINIEKLLTENLTQIEMDAIIHGENPITGISGADCLDEVHKKLSD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q76NS2-1", "uniprot_id": "Q76NS2_DROME", "id": "Q76NS2-1", "name": "Anoctamin", "aln": "-------------------------------------------MYSAVRTNDYDYPESEMDERESLYFDTISLAESEAAAAAAAHRKSISQSRNTIYHSAVDLAGDEGGGGSGGGRLRLGGGAAAEHAALAWQPGYRQSTALEHLNGGGGGGGDHTDAAIAAQMIALQNGRN-HLPTGIGVTGDGGQGGGDDEVSRRLLRTSSNISNKDKKLPITYSQWKSRTYRRFDDGKRSVDFVLAYNG---ETQLEEHRRKCEIFEANLQREGLQLEH---NKVQRVHFIKIHAPAEVLYRYAEILKIKVPLKPIPGQDQIFAESAHEFKTCFSRMCKSLFSSVQLNT------------------------ALFPEREPRIHLEFSRNYLELYDTEHPN-FLDASTRYSIINFILQRQRFVEGEETADNLGIEKLVQDGVYTCAYTLHD---------KDDRDRLLKEWANISKWKNLQPLDQIKDYFGAKVALYFAWLGFYTQMLIPISVFGVLCFLYGFITWNSDPISRDICDD--NGTIMCPQCDRSCDYWRLNETCTSSKFNYLIDNNMTVVFAFSMAIWAVVYLEFWKRYSAGLVHRWGLTGFTHHVE----HPRPQYLARISRTKKLAGKAYEQDHTG------------------KRTILDPDVPFWSFKFLPNFTSYSIMVLFICISVIAIAGIIIYRMAQRASHSILGSENSMTFKVMILPMTAGIIDLIVISLLDMVYSNLAVKLTNYEYCRTQTEYDESLTIKNYVFQFVNYYSSLFYIAFLKGKFVGYPAKYNRVLG-FRQEECNPGGCLMELCMQLVIIMAGKQAVN-AIVEMLIPYLMRTFKELSYRHGWYKSHQDQRLVP-YNQFTEDYNLLPAENNSLYVEYLEMVVQFGFITLFSLAFPLAPLLALLNNVIEVRLDAIKMLRFLRRPVGMRARDIGVWHSIMTVVTRIAVASSAMIIAFSTNLIPKIVYAASMG-DPELNNYLNFTLAVFNTKDFQVQPLLGGSQHVN--ETVCRYTEFRNSPEDPHPYKRPMIYWKILTGRLAFIVIYQNIITMLQGILRWAVPDVSGRLLKRIKRENFLLREHIIEYEKQHAMKLVQTELNGQQKSEGELRQRNNETVIRNRDEATSFV-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : . : . . : . : :: : . :* ** **::* : *:***** .** * **::*:::* . . : : . : :: :**: *:* : *: : .* *: **.* . :** *: :*:*:.**.*** * * :.** : . **:. ::.*** *:.******* ** **: ::.*:: ***. : .. ::*:. . *** ** *.:* : :* :: .:*:** **.*:. *::**. ::* *** . : : *.**** . ***.:* :: . . :: . . ::::*.::. : .:::**:: :: : .: : :. :::* :: ::: :*. :* ** * :*:..::: * :* ::::*.* ::.:.*:**::*:::* *..* :: :* *** .*** ***:** * * *** .: :.*: :* : : . . .: *. * * **:**::*:*::*:* :*****::*****::*:**** *:: :**:. *.:***:*: :: : :::* ..::*:*::::**::** . : :..::*.**: *:. . ***.::* .* . * . :: :*: *:.*:::::*.: :: :: * :**:. : :*::* : * :: * : : . ", "identical_positions": 197, "similar_positions": 274, "identity": "16.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121128-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35308-1", "uniprot_id": "MOT3_MOUSE", "id": "O35308-1", "name": "Monocarboxylate transporter 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MG-AGGPRRGA----------------------------------------------GPPDGGWG-WVVLGACFVVTGFAYGFPKAVSVFFRELKRDFGA---GYSDTAWVSSIMLAMLYGTGPLSSILVTRFGCRPVMLAGGLLASAGMILASFASRLVELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSMLSPLGQLLGERFG-WRGGFLLFGGLLLHCCACGAVMRPP-------------------------------------------------PGPPPRRD-------PSPHGGPAR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RRRLLDVAVCTDRAFVVYVVTKFLMALGLFVPAILLVNYAKDAGVPDAEAAFLLSIVGFVDIVARPACGALAGLGRLRPHVPYLFSLALLANGLTDLISARARSYGTLVAFCIAFGLSYGMVGALQFEVLMATVGAPRFPSALGLVLLVEAVAVLIGPPSAGRLV---DALKNYEIIFYLAGSEVALAGVFMAVTTYCCLRCSKNISSGRSAEGGASDPEDVEAERDSEPMPASTEEPGSLEALEVLSPRAGSPEQEPEEEAVPELDHESIGGHEARGQKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O70461-1", "uniprot_id": "MOT3_RAT", "id": "O70461-1", "name": "Monocarboxylate transporter 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MG-AGGPRRGA----------------------------------------------GPPDGGWG-WVVLGACFVITGFAYGFPKAVSVFFRELKRDFGA---GYSDTAWVSSIMLAMLYGTGPLSSILVTRFGCRPVMLAGGLLASAGMILASFASRLLELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSTLSPLGQLLGERFG-WRGGFLLFGGLLLHCCACGAVMRPP-------------------------------------------------PGPQPRPD-------PAPPGGRAR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HRQLLDLAVCTDRTFMVYMVTKFLMALGLFVPAILLVNYAKDAGVPDAEAAFLLSIVGFVDIVARPACGALAGLGRLRPHVPYLFSLALLANGLTDLISARARSYGTLVAFCIAFGLSYGMVGALQFEVLMATVGAPRFPSALGLVLLVEAVAVLIGPPSAGRLV---DALKNYEIIFYLAGSEVVLAGVFMAVTTYCCQRCSKDIPPGPSAEGGTSDTEDVEAERDSEPMPASTEEPGSLEALEVLSPRAGSPE--PEEEAVPDLSHESVGGHEAHGQNA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O95907-1", "uniprot_id": "MOT3_HUMAN", "id": "O95907-1", "name": "Monocarboxylate transporter 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MG-AGGPRRGE----------------------------------------------GPPDGGWG-WVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDA---GYSDTAWVSSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFG-WRGGFLLLGGLLLHCCACGAVMRPP-------------------------------------------------PGPGPRPR-------RDSAGDRAGDAPGEAEA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGAGLQLREASPRVRPRRRLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDIVARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLV---DVLKNYEIIFYLAGSEVALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTEDAEAEGDSEPLPVVAEEPGNLEALEVLSARGEPTE--PEIEARPRLAAESV----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5K3-1", "uniprot_id": "A0ACD6B5K3_DANRE", "id": "A0ACD6B5K3-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MGGIVEDRETA----------------------------------------------GAPDGGWG-WVVLLGGFVITGFSYAFPKAISVYFKELMHDFGC---GYKDTAWISSIILAMLYGSGPISSIMVNKFGCRPVMLVGGLLASLGMISASFATSIIHLYITAGVITGLGLALNFQPSLIMLGAYFDKRRPLANGLAAAGSPVFLSALSPLGQLLLDQYG-WRGGFLITGGLLLNCCTCGAVMRPL-------------------------------------------------KLKERKACNQELKEMLPPEAGQEN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IVCENNNDKKPSKKKLLDFSVLRDKGLIIYIIAKFIVVLGLFVPTILLVNYAKDQGVPDKEAAFLLSIIGFIDIFARPTCGVVAGLKWVRPKMSYFFSLALLFNGLTDVCSATSTDYKGLIIFCVFFGLSYGMVGALQFEVLMGIVGTSKFSSALGLVLLFEAVAVLIGPPSAGYLV---DKYKNYELIFYMAGGELITAGIFLALASFCCISQKKRKDS--------PQTQQTYVEVNPER---------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W509-1", "uniprot_id": "Q9W509_DROME", "id": "Q9W509-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MVHG---PPARRKSQQQ-------HEACEMDMERQP-----------------------TPPDGGWG-WVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNE---GKGYTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYG-WRGAMLIIGGIVLNCIIFGAMFRPL----------------------------------------ELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLP---------------------KDQYLQLPQRTDTAVSGGALCRS----NSVGHNLKPNLNNNSN----------GAVNGQGPTLVT------------PPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRE----RSASGTMYRP----DALYQGSLHNLPDYVSS------RNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRIILGYISDKPWVN--RLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMY---DLTDSYAPAFLMAGLMIAISGLVMFAIPPLQRLQVRKSERKPHTEHLALS---------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0L6-1", "uniprot_id": "Q9W0L6_DROME", "id": "Q9W0L6-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------MVDTNSSNPGIVGGNSASSARLRRFERTDSELACEEAARLTAEQSPEDEDNQDNDEDDDDEESVYGELPPPPDGGYG-WVICFASFMCNMIVDGIAYTFGIFLEEFVAYFHE---GKGTVAWVGSLLSGVYLSAGPIVSALANKYGCRAVCIAGSIIACIAFVLSTFSTNVSMLMATYGFMGGFGFGMIYLPAVVAVGYYFETKRSLATGIAVCGSGFGTFAFAPLATYLLEEYG-WKNALLIFAGLILNCAIFGAMMRPLTYPKKKKQKPLMQRMYEEKQLQLERGSFAGSHFMVQLPDGTIERKLKMPLNADPGVHSSLNLELLAQQAGGGGLHPVSTLPTITESKVVDVHRQNGAQSPPNGDSNGQLSARSAAGAVGRRPHRNSESENSPYHSQDAMTRNASQPAFLAGDHQSLPKNGSVPAFNTRVRKTSASERFQPSLAAIRATSRGDLEAGAGGDFASSKLSLSQRQGGSQTGSSGRMVRPMSRKDIFYSGSVTNLPQYQSQKSLANYRNSVLSLTKYEKSMQSVAKLDPLAEAEKHREEYDLCPCLGIPDSVKSVVNTMLDVSLLKDPVFMLIGVSNIFGMAGLYVPFVYLVDAAKEHDIPKNDAAMLLSIIGITNTVGRVFCGWVADLPQVN--SLLLNNCCLLVSTIAVTLTPLCYSYAAYITMSIFFGLAISGYISLTSIILVDLLGLDKLTNAFGLLILFRGFAALIGTPLAGAIY---DMTHTYDLPFYMAGALFGISTITSFLAPCLKRCSPSE-ETPVHVETLTPIDEEQGEDAEDDEDQPITIVPKIIKTLASPQQEEGHPQFPQKTSESKL----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q08268-1", "uniprot_id": "MCH4_YEAST", "id": "Q08268-1", "name": "Probable transporter MCH4", "aln": "---------------------------------------------------------------------------------------------------------------------MLNIPIIANSKRFLFSKDHEAQSTRDHDVELETREGPSSGYNPNFNAADAILKKNSDQVDLDVNKLTNVTSRVLNTPEASLIYDDDREFPDGGLKAWLVVFGAFMGLVPVFGLINSLGAIESYISKHQLAN-ISSSTISWIFSLYLAISFLSCILSGGYFDRNGSIGLMCTGTVIYAGGLFALANCKSVWQFILAFSVCSGLGTGILMTPLIGTVATWFLKRRGIATSISTMGGSIGGIVFPIMLRKLYKEVG-FQWAIRILSFICLTCLICASVLARER--------------------------------------------------TKPVVQP------FKSKAEVAK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WYISSVFNWRYFLEGKFLFVAIGASFAESSLTSCATYLASYSMTRGNTENVAYTMITASNAVGILGRYIPGYFAD-KFIGRFNVEIITISMAALFNFVMWLPFGGNTKVLWAYVCLWGFSTGSILSLTPVCIGQISKTTDFGKRYATVYLLQALVTIPVLPIGGTLIG-KGTVANYNHFIIFNSALMAAGAACYIISRHICVGAKLCKF--------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53918-1", "uniprot_id": "ESBP6_YEAST", "id": "P53918-1", "name": "Uncharacterized transporter ESBP6", "aln": "MSTHSNDYFSASSGMVSETSSEVSSINSSQPVSFSKASIAAPVPCSDLHSTKSNDASRKLSISRTLTNRLNDIKKAVDDDNLQTEENSADVNKILESRFDVADAIRLQHNESVQSKLNIPVTHTTTAGASLSAPSSSAFSASSIQNDTTEHKASMDSKLMRNRLYPASTKHSGKDLEAQGITEFEPDEPTVKKVFTNKSTGQLELPPDGGYG-WVVTFCVFLTMFSTWGCNASFGVDLAYYLNHDTYPGASKYDYALIAGLTVFLGQLLSPLVMALMRIIGLRTTMLFGDAVMLAAYLLASFTTKLWQLYVTQGFMVGCSISLIFVPATTVLPGWFLKKRAVAMGVSLLGTGAGGVVYGLATNKMLSDFGNTRWCLRIIGISCSISVLVAIALLKER-------------------------------------------------NPTPAIG------LKSPRAMFEQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKAMFSLKVITKPFVVLIALWFMFALFAYNMMVFTLSSYAISKGLSSHDASTLTAILNGSQSIGRPLMGLAGD--KFGRANVTIVLTTLLTIYMFAFWIP-AHTFVQLIFFSILVGSCVGVANVMNTVLIADMVKPEEFLPAWAFVNYCGAPFLLVCEVIAQALTVEKDKSNPYLHAQIFCGCCFIAALILISILREYSIRMKLTERQAMTNEKLKEWKASEYDTDSADEDWGKLKERKTKYDLLLGPGIKKYFLRMVYPMKV------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **** *:: *: . :.. . : : .: : : * * : . : : : .. * . .: * : :* :* :* .:: * : * : : : . . . : ::. . . . : . : : .. * : : . ..* * .. . . : . * . : : : . : . : . : . * : . . . ", "identical_positions": 20, "similar_positions": 77, "identity": "2.04%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121128-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y3L3-1", "uniprot_id": "3BP1_HUMAN", "id": "Q9Y3L3-1", "name": "SH3 domain-binding protein 1", "aln": "MMKRQLHRMRQLAQTGSLGRTPETAEFLGEDLLQVEQRLEPAKRAAHNIHKRLQACLQGQSGADMDKRVKKLPLMALSTTMAESFKELDPDSSMGKALEMSCAIQNQLARILAEFEMTLERDVLQPLSRLSEEELPAILKHKKSLQKLVSDWNTLKSRLSQATKNSGSSQGLGGSPGSHSHTTMANKVETLKEEEEELKRKVEQCRDEYLADLYHFVTKEDSYANYFIRLLEIQADYHRRSLSSLDTALAELRENHGQADHSPSMTATHFPRVYGVSLATHLQELGREIALPIEACVMMLLSEGMKEEGLFRLAAGASVLKRLKQTMASDPHSLEEFCSDPHAVAGALKSYLRELPEPLMTFDLYDDWMRAASLKEPGARLQALQEVCSRLPPENLSNLRYLMKFLARLAEEQEVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAASVSSIQVVGVVEALIQSADTLFPGDINFNVSGLFSAVTLQDTVSDRLASEELPSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVEDMARRTKRPAPAR-PTMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVGSSLRAPTVPPPLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQVDLGAATA-EGGAPEAISGVPT--PPAIPPQPRPRSLASETN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P55194-1", "uniprot_id": "3BP1_MOUSE", "id": "P55194-1", "name": "SH3 domain-binding protein 1", "aln": "MMKRQLHRMRQLAHTGSSGRTPETAEFLGEDLLQVEQRLEPAKRAAHNVHKRLQACLQGQSGADMDKRVKKLPLMALSTTMAESFKELDPDSSMGKALEMTCAIQNQLARILAEFEMTLERDVLQPLSRLSEEELPAILKHKKSLQKLVSDWNTLKSRLSQAAKNSGSNQGLGGASGSHTHTTTANKVEMLKEEEEELKKKVEQCKDEYLADLYHFSTKEDSYANYFIHLLEIQADYHRKSLTSLDTALAELRDNHSQADHSPLTTAAPFSRVYGVSLRTHLQDLGRDIALPIEACVLLLLSEGMQEEGLFRLAAGASVLKRLKQTMASDPHSLEEFCSDPHAVAGALKSYLRELPEPLMTSDLYDDWMRAASLKEPGARLEALHDVCSRLPQENFNNLRYLMKFLALLAEEQDVNKMTPSNIAIVLGPNLLWPPEKEGDQAQLDAASVSSIQVVGVVEALIQNADTLFPGDINFNVSGIFPGLAPQEKVSSQQVSEELPPVTVPAPATTPAPTPAP--------ASMAVRERTEADLP-KPTSPKVSRNPTETAASAEDMTRKTKRPAPAR-PTMPPPQPSSTRSSPPAPSLPPGSVSPGTPQALPRRLVGTSLRAPTMPPPLPPVPPQPARRQSRRLPASP------------VISNMPAQVDQGVATE-DRGGPEAVGGHPP--PPALPPQPRPRGLISETE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PFG1-1", "uniprot_id": "A0A8M9PFG1_DANRE", "id": "A0A8M9PFG1-1", "name": "", "aln": "----MLKQFNILKQFGNGGKSQDATDLLTEDLVLVEQRVEPAKKAAQIIHKKLVGCLQSQQGLDSERRMKKLPLMMLSVSMAESIKDFDGDSSIRKVLEMCCFMQNTLAQTLADFEMKLEKEVLVPLNKLSEEDLPEILKNKKQFAKLTTDWNNARTR-------------------SETSTGPQAKQHGLREDVEEAWRRLESIKDQYSADLYHFATKEDDYASYFTRLLELQAEYHKASYDFLERNITELKESHS---HTEPLVSSSENKVFGEPLLSHLQSCRRKIAVPIEECVNMLLRTGLREEGLFRLAAAASVMKKLKSSLDSGTVDHTEFSSDPHAVAGALKCYLRELPEPLMTFELYDDWFEAAGEKETDEKLKLLRTALQKLPTENYNNLRYLIQFLSQLSEHQAVNKMTPSNIAIVLGPNLLWP-RCEGETSLLDMASASSVQVVTIIEPLIQHSKSLFPEEADFEVP-VLPESPLSTTSQRPLSDSILPSPPFSSGRPSISKTDSSASSD----DFGVTIVVKSAPVNRDAVVWDNDSDPTDQPLTQDHMPTALPRYTPVLTPSQSQVMPQISCISEPTQDLPTQEPTLKIAGPYKPRRSFIQQKAPNYTKGLLVSPAMSFPTAQTKLPPVPLPRG---SEIKPPLSPKPETMLVPLPTLPEGGPPKKPQGRRPKVPPPQPPQALNKQLSSSAQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:::. * : *. *:: :::::* ***: ****:****:**: :**:* .***.*.* * ::*:****** **.:****:*::* ***: *.*** * :** **: **:***.**::** **.:****:** ***:**.: **.:***. ::* *.: * * . *:*: ** :::*. :*:* ****** ****.**.** :***:**:**: * *: ::**::.*. *: .:: :*:* .* :***. *.**:*** ** :** *::*********.***:*:**.:: *.. . **.***********.*********** :*****:.**. **.. :*: *: . .:** ** .*****::**: *:*.* ******************** . **: : ** **.**:*** ::*.*** :.:*** : :*:*. ::. . . . . .. **. ...: .: : : :. .. ..: : .. . .*.: . . :.*. * :*. *: . . : * *: **. . : . . * . :**. . * *. . . : *. * * : .* : * *: * . **. ***. : * *.::", "identical_positions": 271, "similar_positions": 200, "identity": "38.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121128-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1A5P0-1", "uniprot_id": "BORG5_RAT", "id": "A1A5P0-1", "name": "Cdc42 effector protein 1", "aln": "MPGPQGGTGAPSMSLGKLS-PVGWVPSSHGKR----RLTADMISPPLGDFRHTMHVGRGGDVFGDTSFLSNHGGR------SGNTHRSPRSFLARKLQQVRRVGVPPRRMASPAATSPAPPPISPIIKNAISLPQLNQATYDSLVVSKLSFDSTPASSTDGRSGYGLESGFCTISRLPRVEKHSSRDRDHDRDPDHSQDREQSSSPSEPNPNPELRRSDSLLSFRFDLDLGPSLLSELLGVMSLSEAPAAN-------PPAPAANP-APTAKPPADAVTTLDTVTSLPAP--------------TASSPSSGRFPNGVTAVLGPVAEVKASPVGEGPQVPSKMAFDRR-GASWG-------AIRASRHYTEMDARRELAGVLPQVHGSWESLNEEWSAPPASSRAPVPSTVQANAFEFADADEDDEVKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91W92-1", "uniprot_id": "BORG5_MOUSE", "id": "Q91W92-1", "name": "Cdc42 effector protein 1", "aln": "MPGPQGGTGAPTMSLGKLS-PVGWVSSSHGKR----RLTADMISPPLGDFRHTMHVGRGGDVFGDTSFLSNHGGR------SGNTHRSPRSFLARKLQQVRRVGVPPRRMASPAAPSPAPPPISPIIKNAISLPQLNQATYDSLVMGKLSFDSTPASSTDGHSGYGLESGFCTISRLPRVEKHSNRDR--DRDPDHSQDREQSSFPSEPTPNPELRRSDSLLSFRFDLDLGPSLLSELLGVMSLSEAPAAETPVPTANPPAPAANP-APTAKPPAHAITTLDAVTSLPASAVTSL-----PAPAAASSPSRGHFPNGVTSVLGPAAEAKPSPVGEGPQVPSNMTFDRH-GASWGASRASWGASRASRHYTEMDARRELAGVLPQVHGSWESLNEDWSTPPASVRAPVPTSVQVNAFEFADAEEDDEVKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00587-1", "uniprot_id": "BORG5_HUMAN", "id": "Q00587-1", "name": "Cdc42 effector protein 1", "aln": "MPGPQGGRGAATMSLGKLS-PVGWVSSSQGKR----RLTADMISHPLGDFRHTMHVGRGGDVFGDTSFLSNHGGS------SGSTHRSPRSFLAKKLQLVRRVGAPPRRMASPPAPSPAPPAISPIIKNAISLPQLNQAAYDSLVVGKLSFDSSPTSSTDGHSSYGLDSGFCTISRLPRSEKPHDRDR-------------DGSFPSEPG----LRRSDSLLSFRLDLDLGPSLLSELLGVMSLPEAPAAETPAPAANPPAPTANPTGPAANPPATTANPPAPAANPSAPAATPTGPAANPPAPAASSTPHGHCPNGVTAGLGPVAEVKSSPVGGGPRGPAGPALGRHWGAGWD----------GGHHYPEMDARQERVEVLPQARASWESLDEEWRAPQAGSRTPVPSTVQANTFEFADAEEDDEVKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B274-1", "uniprot_id": "A0A8M2B274_DANRE", "id": "A0A8M2B274-1", "name": "", "aln": "------------MNLGKLSGLKGLVSHSSGKRRFKGDLTPEMISPPLGDFRHTMHVGRGGDVFGDTSFLSNHGGAGNNADAESSTSEKNEGFFTRTLRHVRKT--PDRPRGGSKDLSPPPPAVSPIIKNAISLPRLDVDSPNGCPV-KVLFPSSPKTPENSTYLYGLESGFVTLPRLSRTERPAQGSSPSACPPEIHRGSLTDTNIPSLPCSDSISPSDSMN--SFTLDLGPSLMSEVFALIDSPMCEKPD-----------TISEKAQSVEYNSDSDATTSLVDSLLRE----------------DDDGRTRLYGGEWKNSDFVNDESPKKSTTGDQLRSFPIEDRG---------------------MEPESFQRAADVLARHYG-------------SGGLRNTNTNNSHRRAPYCYPDEDEEIKV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.***** * *. * *** **.:*** ***************************** ...* .. ..*:::.*: **:. * * ... **.**.:***********:*: : :. : *: * *:* :. :. ***:*** *:.**.* *: . . .: .. : ***: : *******:**::.::. . . .: : . . :.: : : . . . .. : .* . . : ... * : : .* * :: :. . **.: . :. . :. . . :. .:**:*:**", "identical_positions": 107, "similar_positions": 106, "identity": "24.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121128-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63472-1", "uniprot_id": "KCNH1_RAT", "id": "Q63472-1", "name": "Voltage-gated delayed rectifier potassium channel KCNH1", "aln": "MTMAGGRRGLVAPQNTFLENIVRRS---------NDTNFVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKSS--ACSFMYGELTDKDTVEKVRQTFENYEMNSFEILMYKKN-----------------RTPVWFFVKIAPIRNEQDKVVLFLCTFSDITAFKQPIEDDSCK---GWGKFARLTRALTSSRGVLQQLAPSVQKGENVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCVFKTTWDWIILILTFYTAILVPYNVSFKTRQ-NNVAWLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVINAFENVDEG---------------------------ISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWMACIWYSIGDYEIFDEDTKTIRNNSWLYQLALDIGTPYQFNGSGSG--KWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDDEVVAILGKGDVFGDVFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFYTAFSHSFSRNLILTYNLRKRIVFRKISDVKREEEERMKRKNEAPLILPPDHPVRRLFQRFRQQKEARLAAERGGRDLDDLDVEKGNALTDHTSAN----HSLVKASVVTVRESPATPVSFQAASTST-VSDHAKLHAPGSECLGPKAGGGDPAKRKGWARFKDACGKGE-DWNKVSKAESMETLPERTKASGEAT-LKKTDSCDSGITKSDLRLDN--------------------------------------------------------------------VGEARSPQDRSPILAEVKHSFYPIPEQT-----------------------------------------------LQATVLEVKHELKEDIKALNAKMTSIEKQLSEILR--ILMSRGSSQSPQDTCEVSRPQSPES-----------DRDIFGAS------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60603-1", "uniprot_id": "KCNH1_MOUSE", "id": "Q60603-1", "name": "Voltage-gated delayed rectifier potassium channel KCNH1", "aln": "MTMAGGRRGLVAPQNTFLENIVRRS---------NDTNFVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKSS--ACSFMYGELTDKDTVEKVRQTFENYEMNSFEILMYKKN-----------------RTPVWFFVKIAPIRNEQDKVVLFLCTFSDITAFKQPIEDDSCK---GWGKFARLTRALTSSRGVLQQLAPSVQKGENVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCVFKTTWDWIILILTFYTAILVPYNVSFKTRQ-NNVAWLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVINAFENVDEVSAFMGDPGKIGFADQIPPPLEGRESQGISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWMACIWYSIGDYEIFDEDTKTIRNNSWLYQLALDIGTPYQFNGSGSG--KWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDDEVVAILGKGDVFGDVFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFYTAFSHSFSRNLILTYNLRKRIVFRKISDVKREEEERMKRKNEAPLILPPDHPVRRLFQRFRQQKEARLAAERGGRDLDDLDVEKGNALTDHTSAN----HSLVKASVVTVRESPATPVSFQAATTST-VSDHAKLHAPGSECLGPKAVSCDPAKRKGWARFKDACGKGE-DWNKVSKAESMETLPERTKAPGEAT-LKKTDSCDSGITKSDLRLDN--------------------------------------------------------------------VGETRSPQDRSPILAEVKHSFYPIPEQT-----------------------------------------------LQATVLEVKYELKEDIKALNAKMTSIEKQLSEILR--ILMSRGSAQSPQETGEISRPQSPES-----------DRDIFGAS------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95259-1", "uniprot_id": "KCNH1_HUMAN", "id": "O95259-1", "name": "Voltage-gated delayed rectifier potassium channel KCNH1", "aln": "MTMAGGRRGLVAPQNTFLENIVRRS---------NDTNFVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKSS--TCSFMYGELTDKDTIEKVRQTFENYEMNSFEILMYKKN-----------------RTPVWFFVKIAPIRNEQDKVVLFLCTFSDITAFKQPIEDDSCK---GWGKFARLTRALTSSRGVLQQLAPSVQKGENVHKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCVFKTTWDWIILILTFYTAILVPYNVSFKTRQ-NNVAWLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYLKTWFVIDLLSCLPYDVINAFENVDEVSAFMGDPGKIGFADQIPPPLEGRESQGISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWMACIWYSIGDYEIFDEDTKTIRNNSWLYQLAMDIGTPYQFNGSGSG--KWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYATIFGNVTTIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTEKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQDDEVVAILGKGDVFGDVFWKEATLAQSCANVRALTYCDLHVIKRDALQKVLEFYTAFSHSFSRNLILTYNLRKRIVFRKISDVKREEEERMKRKNEAPLILPPDHPVRRLFQRFRQQKEARLAAERGGRDLDDLDVEKGNVLTEHASAN----HSLVKASVVTVRESPATPVSFQAASTSG-VPDHAKLQAPGSECLGPKGGGGDCAKRKSWARFKDACGKSE-DWNKVSKAESMETLPERTKASGEAT-LKKTDSCDSGITKSDLRLDN--------------------------------------------------------------------VGEARSPQDRSPILAEVKHSFYPIPEQT-----------------------------------------------LQATVLEVRHELKEDIKALNAKMTNIEKQLSEILR--ILTSRRSSQSPQELFEISRPQSPES-----------ERDIFGAS------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AXZ2-1", "uniprot_id": "A0A8M3AXZ2_DANRE", "id": "A0A8M3AXZ2-1", "name": "", "aln": "--MAGGRRGLVAPQNTFLENIVRRSNVWTFSHRQTDTNFVLGNAQIVDWPIVYSNDGFCKLSGYHRAEVMQKSS--TCSFMYGELSDKETSEKLRQTFENYEMNSFELLMYKKN-----------------RMPVWFFVKIAPIRNEQDKVVLFLCTFSDITAFKQPIEDDSSK---GWGKFARLTRALTSSRGVLQQLAPTVQRGENVLKHSRLAEVLQLGSDILPQYKQEAPKTPPHIILHYCTFKTTWDWVILILTFYTAIMVPYNVSFKTKQ-NNVTWLVVDSIVDVIFLVDIVLNFHTTFVGPAGEVISDPKLIRMNYVKTWFVIDLLSCLPYDVINAFENVDEG---------------------------ISSLFSSLKVVRLLRLGRVARKLDHYIEYGAAVLVLLVCVFGLAAHWLACIWYSIGDYEVIDQDANMVRTDSWLYLLGEAVGQPYHFNASGSG--KWEGGPSKDSVYITSLYFTMTSLTSIGFGNIAPTTDGEKIFAVAMMMIGSLLYATIFGNVTNIFQQMYANTNRYHEMLNSVRDFLKLYQVPKGLSERVMDYIVSTWSMSRGIDTDKVLQICPKDMRADICVHLNRKVFKEHPAFRLASDGCLRALAMEFQTIHSAPGDLIYHAGESVDSLCFVVSGSLEVIQDDEVVAILGKGDVFGDVFWKEVNLAQSCANVRALTYCDLHIIKRDALQKVLEFYTAFAGHFSRNLVLTYNLRKRIVFRKISDVKREEEEMLRRKNEAPLNLPPDHPVRRLFQRFRQQREARLAAERAN--QVEQDVEKG--KSEQTVVK----EITSPTSIITVTESPATLNTLSPTTPSTKTLCRAKLNTPLAPNTAQKS--AEAPKSKGWSRFKEATAKSDLSLSSVSKAESMEMLPDRTKSQDELLSLKKTDSCDSGITKSDPRLDN--------------------------------------------------------------------MGSAETPQDRSPVQPEEKRLFYPIPEHS-----------------------------------------------LQACFSELRQDLQGDIHSLGCRMSALEGQLAEMLR--LLAERNSS-GPAELHHISRPNSPDS-----------EKDDNISS------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q02280-1", "uniprot_id": "KCNAE_DROME", "id": "Q02280-1", "name": "Potassium voltage-gated channel protein eag", "aln": "--MPGGRRGLVAPQNTFLENIIRRSN------SQPDSSFLLANAQIVDFPIVYCNESFCKISGYNRAEVMQKSCRYVCGFMYGELTDKETVGRLEYTLENQQQDQFEILLYKKNNLQCGCALSQFGKAQTQETPLWLLLQVAPIRNERDLVVLFLLTFRDITALKQPIDSEDTKGVLGLSKFAKLARSVTRSR----QFSAHLPTLKDPTKQSNLAHMMSLSADIMPQYRQEAPKTPPHILLHYCAFKAIWDWVILCLTFYTAIMVPYNVAFKNKTSEDVSLLVVDSIVDVIFFIDIVLNFHTTFVGPGGEVVSDPKVIRMNYLKSWFIIDLLSCLPYDVFNAFDRDEDG---------------------------IGSLFSALKVVRLLRLGRVVRKLDRYLEYGAAMLILLLCFYMLVAHWLACIWYSIG-----RSDADNGIQYSWLWKLANVTQSPYSYIWSNDTGPELVNGPSRKSMYVTALYFTMTCMTSVGFGNVAAETDNEKVFTICMMIIAALLYATIFGHVTTIIQQMTSATAKYHDMLNNVREFMKLHEVPKALSERVMDYVVSTWAMTKGLDTEKVLNYCPKDMKADICVHLNRKVFNEHPAFRLASDGCLRALAMHFMMSHSAPGDLLYHTGESIDSLCFIVTGSLEVIQDDEVVAILGKGDVFGDQFWKDSAVGQSAANVRALTYCDLHAIKRDKLLEVLDFYSAFANSFARNLVLTYNLRHRLIFRKVADVKREKELAERRKNEPQLPQNQDHLVRKIFSKFRRTPQVQAGSKELVGGSGQSDVEKGDGEVERTKVFPKAPKLQASQATLARQDTIDEGGEVDSSPPSRDSRVVIEGAAVSSATVGPSPPVATTSSAAAGAGVSGGPGSGGTVVAIVTKADRNLALERERQIEMASSRATTSDTYDTGLRETPPTLAQRDLIATVLDMKVDVRLELQRMQQRIGRIEDLLGELVKRLAPGAGSGGNAPDNSSGQTTPGDEICAGCGAGGGGTPTTQAPPTSAVTSPVDTVITISSPGASGSGSGTGAGAGSAVAGAGGAGLLNPGATVVSSAGGNGLGPLMLKKRRSKSRKAPAPPKQTLASTAGTATAAPAGVAGSGMTSSAPASADQQQQHQSTADQSPTTPGAELLHLRLLEEDFTAAQLPSTSSGGAGGGGGSGSGATPTTPPPTTAGGSGSGTPTSTTATTTPTGSGTATRGKLDFL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.*****************:*** *:.*:*.******:****.*:.***:***:********. .*.******:**:* ::. *:** : :.**:*:**** . *:*:::::******:* ***** ** ****:****:.:. * * .***:*:*::* ** *::. : :: *:*.**.::.*.:**:***:**********:****.**: ***:** *******:*****:**.: ::*: ***********::*************.***:****:*****:*:**:***********:***:. :: *.****:************.****:*:*****:*:**:*.: *.***:******** .*:. ***: *. ** : *.. : .***:.*:*:::******.:**:****:*. ** **:*::.:*:*.:********:**.*:*** : * :**:***.**:*:**::***.********:****:*::*:**:***: *****:************:******************.* *.*****:**:***:*****:*:*********************** ***: :.**.************ **** * :**:**:**: *:***:******:*::***::*****:* :****. * ** **::*.:**: :.: .::. : ***** ::: . . : :: :: ...:..* : : : . . .. . : .. . ... *:**: * . : ..:*: *:*: :: * : * :* ::* . . . .: : *: : : ::* . : : : . :: . : . : :** : :.* :. ", "identical_positions": 484, "similar_positions": 259, "identity": "39.74%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121129-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TDX6-1", "uniprot_id": "CGAT1_HUMAN", "id": "Q8TDX6-1", "name": "Chondroitin sulfate N-acetylgalactosaminyltransferase 1", "aln": "-----------------------MMMVRRGLLAWISRVVVLLVLLCCAISVLYMLACTPKGDE--EQLALPRAN-------------------SPTGKEGYQAVLQEWEEQHRNYVSSLKRQIAQLKEELQERSEQLRNGQYQASDAAGLGLDRSPPE-KTQADLLAFLHSQVDKAEVNAGVKLATEYAAVPFDSFTLQKVYQLETGLTRHPEEKPVRKDKRDELVEAIESALETLNSP---AENSPNHRPYTASDFIEGIYRTERDKGTLYELTFKGDHKHEFKRLILFRPFGPIMKVKNEKLNMANTLINVIVPLAKRVDKFRQFMQNFREMCIEQDGRVHLTVVYFGKEEINEVKGILENTSKAANFRNFTFIQLNGEFSRGKGLDVGARFWKGSNVLLFFCDVDIYFTSEFLNTCRLNTQPGKKVFYPVLFSQYNPGIIYGHHDAVPPLEQQLVIKKETGFWRDFGFGMTCQYRSDFINIGGFDLDIKGWGGEDVHLYRKYLHSNLIVVRTPVRGLFHLWHEKRCMDELTPEQYKMCMQSKAMNEASHGQLGMLVFRHEIEAHLRKQKQKTSSKKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BJQ9-1", "uniprot_id": "CGAT1_MOUSE", "id": "Q8BJQ9-1", "name": "Chondroitin sulfate N-acetylgalactosaminyltransferase 1", "aln": "-------------------------MVRRGLLGWISRVVILLVLLCCAISVLYMLACTPKGDQ--EQLGLPRAN-------------------GPTGKDGYQAVLQEREEQHRNYVNSLKRQIAQLKDELQARSEQFRSGQDQASDATSLRSGWDREP-KAQADLLAFLRGQVDKAEVHAGVKLATEYAAVPFDSFTLQKVYQLETGLTRHPEEKPVRKDKRDELVEAIESALESLNSP---VESSPHQRPYTAADFIEGIYRTERDKGTLYELTFKGDHKHEFQRLVLFRPFGPIMKVKKEKLNLANTLINVIVPLARRVDKFRHFMQNFREMCIQQDGRVHLTVVYFGKEEMNEVKGILENTSKAANFRNFTFIQLNGEFSRGKGLDVGARFWKGSNVLLFFCDVDIYFTSEFLNTCRLNTQPGKKVFYPVLFSQYNPGVIYGHHDAVPPLGQQLVIKKETGFWRDFGFGMTCQYRSDFINIGGFDLDIKGWGGEDVHLYRKYLHSNLIVVRTPVRGLFHLWHEKHCMDELTPEQYKMCMQSKAMNEASHGQLGMLVFRHEIEAHLRKQKQKASSKKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F6G2-1", "uniprot_id": "E7F6G2_DANRE", "id": "E7F6G2-1", "name": "Hexosyltransferase", "aln": "MVQRDASTLLNCVFLPVLLLRLPVVMLRRGLLAWLSRLGVLLVVVCCCLSLLYVITCSPHADDPMAGQPLPRAGGMALAGGPSRPGGVGGAPVGPAGREGFQALLQEREEQHRQHIASLKKQIAQLKEALQERSEQLKGMQDSLEKSTGKGMGGDVAEDRSHSDLQQFLRSQLSRAEVHTGVRLPSEYAVVPFESFTLQRVYQLEMGLTRHPEEKPVRKDRRDELGEVVESALHALNAPNHGREKTKASKVYTPSDFIEGLARTEKDKGSLYELTFRGEHKHELRRLVLFRPFGPLMKVKSELVETSHMPINIVLPLSQRADKFRQFMHNFREVCVKQDGRVHLTVVYFGKDQMNEVKGTLENTSRELNFRNFTLIQLNEEFSRGRGLDVGARAWKGGNVLLFFCDVDIIFTADFLNTCRLNAQPGKKVFYPVLFSQYNPAVIYGSHDHVPPVDQQLIIKKDTGFWRDFGFGMTCQYRSDFINIGGFDVDIKGWGGEDVHLYRKYLHSNLLVVRAPSRGLFHLWHEKRCADELPPDQYKMCMQSKAMNEASHGQLGMLLFRHEIEAHLRKQKQRSGAKKA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*****.*:**: :***::**.:*:**:::*:*:.*: ****. .*:*::*:**:*** *****::: ***:******: ** ****::. * . ..::. . . ::::** **:.*:.:***::**:*.:***.***:*****:***** **************:**** *.:****.:**:* *.: : **.:*****: ***:***:******:*:****::**:*******:****.* :: :: **:::**::*.****:**:****:*::**************:::***** *****: ******:**** *****:******* ***.*********** **::********:*****************.:*** ** ***: ***:***:**************************:*********************:***:* **********:* ***.*:**********************:**************::.:**:", "identical_positions": 366, "similar_positions": 120, "identity": "63.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121129-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B7ZCC9-1", "uniprot_id": "AGRG4_MOUSE", "id": "B7ZCC9-1", "name": "Adhesion G protein-coupled receptor G4", "aln": "MRKHILHQRLCGLILVSSFIFLTDSLSLKGKRLDFYGEGKAYVSLTYTMPELSRLTACIDLISMTNSSHYWMAFIYITNNTLLGREDVDLGLAGDHQQLILYSFGKTFYVSYHLIPFHWHTLCLVWDGVKGRLELFRNKE--RILAIMDQPHRLSPNGTLVLGHFPRNGEGQIKTVIPR-FTSSLYYFQLWDRILE--NEEFMTCFYGNVVSWEDDVWLIHKISPTVDRRLRCFVSENMTIQETSTNVSQQIDLTTSSQTTGLNPHKTSHSSTLLPEGMADSTINSTAISYANTVPSPLATVSAAKDLKTSTTETATFLTDTLFTSTATPLPTQTVTEHSYLG-----------KTRTSKRVEAMATEIFHSATATDLIDTSVFTKNYTVSETSTTKSKSAVGKTTLFLN--ESTSIAPTPCPKHKSTDVAILHTSKSGQEFLVSSAARTVSWSTLEETSPITTDVGIVSTFPPESLLTSTASPVSSTFPEIQLASTLSTTDSEMASTVHSVLP----MQTIPTPRTVKPESGSTNFQDVFSPSMEDALSVSMPKETTFMAFSSITSSPITRTQDEQIAIDAESTHLTIIPGTKFVPTLAEASLFPTIEGQAYTQDTPTTDEPMLTLTSTKSPSTYNASESVLTSITIKSDYQFFTNETTWTSKSGQNLLTSMNTTTIPTFTSNKTLTLPFQGNATNRDHSSMTTNVSPIEASTESKVTTSSDATTASYTTALFKPTSQWLSHFTSVSGITSIASQPESKLTTLLLKSNSMPTVATNEFPSIPSEPVAPSVN-TSTLTDIKPNFSTEKSISETIQIETNGVSSFGDTLAPLPMSATTQRVYTTVT-KETTSRHPKVKSTISTVAEASPFSTMLEVTDESEQMVTASVTISPFTDIEKLTTALSKETATAEVGVSWLSTKLKESMPESSHNGTTESFNSTHTYTVDWTSEKSKGNSASSPNSASTQALPELPSSSTMKTMGVTFSTNSSQRTAASLSAGILSPQTASTHALVTPQLLTHTFSLPVNISAVTSPKTTMVFFDETKVTLSQPSTLARDFTTSMPSVGSTLPTVTMTTELVPPVSPTASTISDSMFTHRDLLHTTSEVTTISSTTAHMAISSLRETLVSSLRPPTPVITKAISTIPSISSDSVSPSIHTLVCSRPSPNNVTIVSSTYVSSTTSTSVATP--------SESHFSFPYAFSSGGDVT-MASGPTGTSAGGEAMPPNTFVNKFITSVD---HESTTYFVNTPVSTQSVFATSMVSSDKEQTNISMEKTLRTTGVAEISPSKNSFILDSQSTFPWEMTDTELSETTEISSHQTHLPSEILPGYSDSGNLTTFSTSGSTQSAQTLSSSTIIGVRVSEGSTSLEKTALPSQVQTVTKSLTHDKERTSALSEYPPRTVEKIMSSSPVTHQATGHLATSIVDASR--TTRISHPVLINTTLSYLLSLKTKPEATQIASSTSGSTENFPNSFSPFTTGLLSTNFTMITPNGSTTVLSIPNEPTNLPKKTSMEASTPISQMDLLALNVTAFTSKKVSDTHTMLMTKSSRTIHIGTLKSVSIGTFGLKSEKSEMPVNNSDFSTTVLYSDTSTRLGEFFTSSSSLPPKATKTTQASTLNTTPVAHAGPTSQRTVFSSTFSNSSVVEVPLNYTTAHFSSPTQRGFLSMKTIPTTSMAGISTSVIGATSSSLSSSKNTEPISSIPKTMFSLLLSTTQQPSQENGAPTLDILPGIT------VSSGGATDLINANSRATIPANELSTTPSDNFYTFLNTQDSPTLTNSKVTPRPTESVKSTPTHLSFDTRKMN---ILTELTKSGPCVTTPVLYPLWT-QTSTAPPLTSHLYSPHSTKAKF-------PLASQMAEYPAWATGITPSITQALLTTSRNTQRVEDSPFPVFTTK-VMTPNRMEVETLHSPSGTLATSTTSQIGLVSRDVTVMPLISTSESLPSLGISESTSLSISSTFPPTTLAAILPTFEKTAMPVTPGITLSSNPS------VNSRATSPTWSSSSLPSDSR-ASIFTPSRLLTSSSGEMSESTFPASDIIATYSNFTVAPLSDG-SATIATQATSTTTLDIITANSLTSPPIPSKDKDGSLHTSTFLESSLRTTGADSSTDMSERMSFGRTSISPSLTRHDLSIGSLTVSSPTNTSPWSKVPVTSESHTLFPSKSTLDSVMSTATTTSTAIGTSFPLMSTEMAHPSTATGFSLVSSSFETTWMDSIFSSLFTQPSTSPTAKESTVSFYNIKMSFSVFDEEPRVLVTTVIHDLTKDWLNFMFQNSEFSLANLAIQIKSRKTSKEETAMYRYILEQKKGQGMDAIFHVPYSCACWVIIKAKSSLESVELISSIRTKIHGNLTHGNFTQDQLTLLVKSDHVVVEKLEPGKCEADETPSKYKGTYKWPLTDPTETAQERCIKNENRNATRICSISIQTGKCQWEKPRLKQCKLLQGLPDKIVDLANITISDENADDVAEHILNLVNESPPLDEEETKIIVSKVADISNCDEISINLTQIILQILNTVTEKQSDSASNLPPVSNEILRIIERVGHKMEFAGRTANLTVAKLALAVLRVDH-KFEGMAFSIQSSEEVIAPQIFLGD----IPLRKALASIYLPKSLREKVPLDGLQT-ILFNFFGQTSLFKAKTITSELMTYVVSASISN-TSIQNLADPVIIILKHIQGDWNYDQVYCAFWDFDTNNGLGGWNPSGCKLKESNINYTICQCNHLTHFGVLMDLSRSTVDAVNERILVIITYTGCGISSIFLGIAMVTYIAFHKLRKDYPSKILINLCTALLMLNLAFLVNSWLTSFQKVGLCITAAVALHYFLLVSLTWMGLEAVHMYFALVKVFNTYIPNYILKFCLAGWGIPAITVAIILSVRKDLYGT------LSPTTPFCWIKDDHIFYISVVAYFCLIFLMNLSMFCTVLVQLTSVKSQSQKTRKKMILNDLKGTISLTFLLGLTWGFAFFAWGPVRIFFLYLFAICNTLQGFLIFVFYCVMKESVREQWHMPLHCRWLRLENFAG-----WINVRHKQKRLKKNNESKLLTPSLMSTTT---FKSIGSVPSIPSEINFSNGDFDDSPDTFSFLSCKAAPTFIRRALPAEIQTNSTQKQRSFPINVSRDTHLTPSSGLGEMFNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IZF6-1", "uniprot_id": "AGRG4_HUMAN", "id": "Q8IZF6-1", "name": "Adhesion G protein-coupled receptor G4", "aln": "MKEHIIYQKLYGLILMSSFIFLSDTLSLKGKKLDFFGRGDTYVSLIDTIPELSRFTACIDLVFMDDNSRYWMAFSYITNNALLGREDIDLGLAGDHQQLILYRLGKTFSIRHHLASFQWHTICLIWDGVKGKLELFLNKE--RILEVTDQPHNLTPHGTLFLGHFLKNESSEVKSMMRS-FPGSLYYFQLWDHILE--NEEFMKCLDGNIVSWEEDVWLVNKIIPTVDRTLRCFVPENMTIQEKSTTVSQQIDMTTPSQITGVKPQNTAHSSTLLSQSIPIFATDYTTISYSNTTSPPLETMTAQKILKTLVDETATFAVDVLSTSSAISLPTQSISIDNTTNSMKKTKSPSSESTKTTKMVEAMATEIFQPPTPSNFLSTSRFTKNSVVSTTSAIKSQSAVTKTTSLFSTIESTSMSTTPCLKQKSTNTGALPISTAGQEFIESTAAGTVPWFTVEKTSPASTHVGTASSFPPEPVLISTAAPVDSVFPRNQTAFPLATTDMKIAFTVHSLTLPTRLIETTPAPRTAETELTSTNFQDVSLPRVEDAMSTSMSKETSSKTFSFLTSFSFTGTESVQTVIDAEATRTALTPEITLASTVAETMLSSTITGRVYTQNTPTADGHLLTLMSTRSASTSKAPESGPTSTTDEAAHLFSSNETIWTSRPDQALLASMNTTTILTFVPNENFTSAFHENTTYTEYLSATTNITPLKASPEGKGTTANDATTARYTTAVSKLTSPWFANFSIVSGTTSITNMPEFKLTTLLLKTIPMSTKPANELPLTPRETVVPSVDIISTLACIQPNFSTEESASETTQTEINGAIVFGGTTTPVPKSATTQRLNATVTRKEATSHYLMRKSTIAAVAEVSPFSTMLEVTDESAQRVTASVTVSSFPDIEKLSTPLDNKTATTEVRESWLLTKLVKTTPRSSYNEMTEMFNFNHTYVAHWTSETSEGISAGSPTSGSTHIFGEPLGASTTRISETSFSTTPTDRTATSLSDGILPPQPTAAHSSATPVPVTHMFSLPVNGSSVVA--------EETEVTMSEPSTLARAFSTSVLSDVSNLSSTTMTTALVPPLDQTASTTIVIVPTHGDLIRTTSEATVISVRKTSMAVPSLTETPFHSLRLSTPVTAKAETTLFSTSVDTVTPSTHTLVCSKPPPDNIPPASSTHVISTTSTPEATQPISQVEETSTYALSFPYTFSGGGVVASLATGTTETSVVDETTPSHISANKLTTSVNSHISSSATYRVHTPVSIQLVTSTSVLSSDKDQMTISLGKTPRTMEVTEMSPSKNSFISYSRGTPSLEMTDTGFPETTKISSHQTHSPSEIPLGTPSDGNLASSPTSGSTQITPTLTSSNTVGVHIPEMSTSLGKTALPSQALTITTFLCPEKESTSALPAYTPRTVEMIVNSTYVTHSVSYGQDTSFVDTTTSSSTRISNPMDINTTFSHLHSLRTQPEVTSVASFISESTQTFPESLSLSTAGLYNDGFTVLS-DRITTAFSVPNVPTMLPRESSMATSTPIYQMSSLPVNVTAFTSKKVSDTPPIVITKSSKTMHPGCLKSPCTATSGPMSEMSSIPVNNSAFTPATVSSDTSTRVGLFSTLLSSVTPRTTMTMQTSTLDVTPVIYAGATSKNKMVSSAFT-TEMIEAPSRITPTTFLSPTEPTLPFVKTVPTTIMAGIVTPFVGTTAFSPLSSKSTGAISSIPKTTFSPFLSATQQSSQADEATTLGILSGITNRSLSTVNSGTGVALTDTYSRITVPENMLSPTHADSLHTSFNIQVSPSLTSFKSASGPTKNVKTTTNCFSSNTRKMTSLLEKTSLTNYATSLNTPVSYPPWTPSSATLPSLTSFVYSPHSTEAEISTPKTSPPPTSQMVEFPVLGTRMTSSNTQPLLMTSWNIPTAEGSQFPISTTINVPTSNEMETETLHLVPGPLSTFTASQTGLVSKDVMAMSSIPMSGILPNHGLSENPSLSTSLRAITSTLADVKHTFEKMTTSVTPGTTLPSILSGATSGSVISKSPILTWLLSSLPSGSPPATVSNAPHVMTSSTVEVSKSTFLTSDMISAHPFTNLTTLPSATMSTILTRTIPTPTLGGITTGFPTSLPMSINVTDDIVYISTHPEASSRTTITANPRTVSHPSSFSRKTMSPSTTDHTLSVGAMPLPSSTITSSWNRIPTASSPSTLIIPKPTLDSLLNIMTTTSTVPGASFPLISTGVTYPFTATVSSPISSFFETTWLDSTPSFLSTEASTSPTATKSTVSFYNVEMSFSVFVEEPRIPITSVINEFTENSLNSIFQNSEFSLATLETQIKSRDISEEEMVMDRAILEQREGQEMATISYVPYSCVCQVIIKASSSLASSELMRKIKSKIHGNFTHGNFTQDQLTLLVNCEHVAVKKLEPGNCKADETASKYKGTYKWLLTNPTETAQTRCIKNEDGNATRFCSISINTGKSQWEKPKFKQCKLLQELPDKIVDLANITISDENAEDVAEHILNLINESPALGKEETKIIVSKISDISQCDEISMNLTHVMLQIINVVLEKQNNSASDLHEISNEILRIIERTGHKMEFSGQIANLTVAGLALAVLRGDH-TFDGMAFSIHSYEEGTDPEIFLGN----VPVGGILASIYLPKSLTERIPLSNLQT-ILFNFFGQTSLFKTKNVTKALTTYVVSASISDDMFIQNLADPVVITLQHIGGNQNYGQVHCAFWDFENNNGLGGWNSSGCKVKETNVNYTICQCDHLTHFGVLMDLSRSTVDSVNEQILALITYTGCGISSIFLGVAVVTYIAFHKLRKDYPAKILINLCTALLMLNLVFLINSWLSSFQKVGVCITAAVALHYFLLVSFTWMGLEAVHMYLALVKVFNIYIPNYILKFCLVGWGIPAIMVAITVSVKKDLYGT------LSPTTPFCWIKDDSIFYISVVAYFCLIFLMNLSMFCTVLVQLNSVKSQIQKTRRKMILHDLKGTMSLTFLLGLTWGFAFFAWGPMRNFFLYLFAIFNTLQGFFIFVFHCVMKESVREQWQIHLCCGWLRLDNSSDGSSRCQIKVGYKQEGLKKIFEHKLLTPSLKSTATSSTFKSLGSAQGTPSEISFPNDDFDKDP------YCSSP---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7N0-1", "uniprot_id": "A0ACD6B7N0_DANRE", "id": "A0ACD6B7N0-1", "name": "", "aln": "MITFKKYLPVTIYMWMYGSSFIYAESLWGTKKAFTIRSCIWQLNENVIIPPLEELSVCVNLMRVLTTS-EWTAFDYKGP----GQQHVELGLAGNGGNLKASIFGKEWTVAYDLAKNNWHVVCLTWSSHTRLFQVIVNNRSFEFPLNETSPRYLAANGTLSLGVSHSFVGGNIVFETGKNFLGDMSLFRIWKEQMSALQLAEFRCVDGNIVTWRTQDWDYQKCPSLPDNSLKCESSKYKIQMHLSITQNTNNDNTD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SQEMVLSWLKYIFHPKIMVHSVSLSSKSLQTGADLTGENMEAVQEKPR-----------------------------------------------------------------------------------------------------------------------IKTQWFDCVVFVRVIPEEDVSITVSTIKTLLIPSYSYSADIVLMTNPVSINILSVAVLPNVTSSPAVSTISPVFSQT----------------TNIPGIGSTNITTVVTLMSSLRTQAMDKICLIS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSFTLNKEFGDIFYRVNLNITMSGSITD-----------------------------------------------------------------------------------------------PKHTIEQWLQETLQRCR-------------------------------------MDVWNIVIKGAPKYKTTFQVQALAPVN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ETATERLIFELLTQG---------------------------------------------YINASIAISVPTDEVNITQIDPGLCPEEAMLTVYG-MYMWPSMTAQSQYELTCVKG-NESATRFCKLNEATDKAIWEAPDMSKCLKTVSDFG---DLENITVTPGNSEYIVDMIEDLLNEQTGLSNAQLDIMLEKLSEVTEVGTLTPDLSSSITNIVSEICHITTN----LTQVTNKILSITDLMGDRTVFAGDAHNMTAPSLALQLINPDTSQFHGLTFEVSSVQNDGTPEIFYDENFTENPDTGTVAFISLPPTIENFFPNSGARPRVQFHFYGKEKLFEDTSSNLTLNSYVVSASVTN-ATVSELEIPVMVTLRHLQNKEDWDIVKCVYWDFNKNDKKGGWNDRGCEIVNSNATQTSCSCDHLTHFGVLLDISKTPINPKDEWVLTIISYVGCGISSIFLGVTLLTYLAFEKLRRDYPSKILINLCMALLGLNMLFLVNSWFASFNSNALCITVAAFQHYFFLATFTWMGLGAINMYLALVKVFNSYVPSYILKFCAVGWGIPLSVVILVLAIDFNSYGTSLSTDLLQESTAFCWFKNDVTFYVTVVSFAILIMVCNIIVFVVVLVQIHKMRVNKPSSSRKGFLHDLRVVASLTFLLGLTWILVFFGWGPAKTPLMYLFSILNSLQGFFIFLFYCLMKDNVRKQWRMHLCCGRFRESEYSD--------WSRSVPKGDKGKGGLQVSSSMKSEITSERKISDTSNTGTSNDDFLKQESKQ-----------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : : : : . *: *: :. :* *..::.*::*: : .* * ** * *::.::*****: :* :** : : :.* :**.:** *.. . :::: *:. .: .*: *:.:*** ** .:: * ..: *::*.. :. : : *. **:*:*. : * :* . *. *:* .: . * . . : * * * : * : :. ...* :..*..:: : . : : : *. :. . * : . .:. *:.* *:*. . :*. . ::: .: .. * . . : :* :.: . . .::. : . :. . : * * *: .* *:. * .*:. ** :. *. * * .: : : . : . * :: * ..:. * . * *:* : : .::: * :.* : :::** * : : * * * . . : *:*. : .***:*.:. *.*. ** * :.:* . ** ***:: *:: :.: * :*:**.. *.: : .*::.*:::::: . :: :*: : :*:. : . .: * ::*:** * : *.: *:* *:*.. *** ::. * *.*::*.: * :: *:** .: * :* * ** :: : .* .. :. : *:*:*: .**: .. . * :******::: :.:* **:: *:*: .. ::. * *.:***:.*: **** **:: ::* . * *.*:********:*:*::.::. :* :*.:*:*.**********::::**:**.***:***:******* *** **: **:***::**:. .:***.*. ***:*.::***** *::**:******* *:*.****** .***** * : ::: : *** *. :*.***:*:* **::**:: **:: *: :* .****: .:: : .: :* :*:**: . ********** :.**.*** : ::***:* *:****:**:*:*:**:.**:**:: * * :* .: :. . .* ::.*: * * * * . ..: : : . : ", "identical_positions": 336, "similar_positions": 414, "identity": "10.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121129-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LEZ9-1", "uniprot_id": "A0ABK0LEZ9_RAT", "id": "A0ABK0LEZ9-1", "name": "", "aln": "MLPILKVCGKSGDYPSPAPPRPPGSLPRRRPRQKRRRLRSAAQEPPVVLNFSLKMADPTFAGTTNGTSLRGLRERLVAVAQELAEERRRKRG-LESSAVSLK--KSSCTPVLDGSVLKNDVKQQLAKERRE------EQKRQQEANKEKQLLEKEQKAKLQYEKQLEEKHRKLKEQKEKDERRRASAEEKRKQKQAEDKEKFKAVVSRTMERCNLIDKRQ-KRWSWEGSVMNTDKS--------------------------------------------GKPENKRSSSMSRKENQLQTSGDLQHVNNRP------------------------------------------------------SMTKYVFRYVTVPMFTSE-ELKSSAMFCKPSAKAPVTAKLEV---------------------------------TPIKKVETPLKGDVEGPAKVVNLEIPPKITIEVPSPTNLEEPSEGDVEVKLQNMEDISKVK-----------------------------------------VEISPEADVKVSIDENIARYPKP-----------------------------------------------------------------NVEELPSVSMDASSSIEPSSTVSEDSFP-------------SPSTASSSFVSVEISPVVSLDASPETSID---------------ASPESSMDSGSMEVALGNNLEAPLQASEESYFDESVQEQP--------QNPEMDKRN--VNLNLTTKKQAPCHIPCYRWPSSPALGWRPPSPLKA-LQSRKIRPPSPLPVSS----------------RLSTKTSLSYRITPVQNILYVPNALGIIAAKKDNIQK-----------HMIQKESGYKSMP---SGEVAKKALVQVQHAAYEQKGKKEKERVQKEEIKQSIARK-------SEVMEKKLNEVPAGESSPRKD-EQREKDPTKPLLELPEDQKEQLQKGDSAMMNPH------DSAEQRKKEQERIMLQNWQERLERKKRVEEIMKWTRKTDENTSKASEISSS--SEDDADDEDETGSEDSVEMLPSG-RKMSMKHKKFHK---YAKMKPQKLVFLQAGTGEVDTEKNVYFNGDVKDAKQKDPKYSTIQAKVSKISTKRPPTRPIRSRKIKEGGTTIRPTQSVTTS--HQWFCDKLIDLSHTTESPVVKTTPG-NNKQSSTDPKISHQGPQAPADHKKRVKAVSAPLTEVFSHLHIAGRATNLEHPFASSYSRLAFGGEVEDSDV--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AEY4-1", "uniprot_id": "MA7D3_MOUSE", "id": "A2AEY4-1", "name": "MAP7 domain-containing protein 3", "aln": "------------------------------------------------------MADPTFAATSSSTSFRGLHERLVAMTQELAEERRHKRG-INSSAGANK--RSSSTP--DGSVLKNDVKQQLAKERRE------QQKRQQEANKEKQLLEKEQKAKLQYEKQLEEKHRKLKEQKEKDQRRQASAEEKRKQKQAEDTEKFKAVVSRTLERCNRIDQRQ-KRWSWEGGVMNADKS--------------------------------------------GKLENKRSSSLSRKDNRLHPRGDMQHVDNTP------------------------------------------------------GMTKYVFRYVTAPVFSSD-EIKSSAMFCKPSAKTPVAAKLEK---------------------------------ITTKKLDASLRGHVEG-LSMMNIEIPPKITIEVPSPPKLEESSEADAEVRLQTMDDISKVK-----------------------------------------EDASQKVDIKVPTDENIARHPKP-----------------------------------------------------------------NVEELSPVSVDTSSSVELSSIVSVNSSP-------------SLSTGSFSFGSVEISPVVSIDASLETNID---------------TSPELSMDSGNTKVASEIKTEAPLQARGESRLEASVEGQPEANVEGSPKNPEIDKR----NINLTTKKQPLCHIPCYRWPSSSALGCRPPSPLKA-LQTRKIRPPSPIPVSS----------------KLSTKTSLSYKITPVQNVLYVPNSLGVIATKKETIQK-----------YPIKKEFGNRSMP---SAEAIKKAFIQIRHAAYEQ-SKNEKERLQKEETKQRIARK-------PEIMAEKLDKVPAEGSLPCQD-EQQDKNPTKTFLESPEVQKAELQKGDSAMMKSR------DSAEQRKKEQE-NILQHWQERLERRK------------------ASEISFS--SEDEADDEGE--SEDSLEIFPSGGKMLSMKLKKFHK---YAKTKPQKLVFLQSGTDEVDTNKNVYFNGDMKAVKQKDPKYSMIQGKGSKLSAKKPPTRPIRSRKTKEGSTAIRPTQSASSNPNHKWVCDKVIDFNQT---PFLKTTLTKSNKESPADSKIACQGPQAHLDHRKRTKSVSVPLTNVLSHLHITGRASNLEHPFASVYSRLAFGKEAEESDV--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWC1-1", "uniprot_id": "MA7D3_HUMAN", "id": "Q8IWC1-1", "name": "MAP7 domain-containing protein 3", "aln": "-----------------------------------------------------MMADGAAAGAGGSPSLRELRARMVAAANEIAKERRKQDV-VNRVATHSSNIRSTFKPVIDGSMLKNDIKQRLARERRE------EKRRQQDANKETQLLEKERKTKLQYEKQMEERQRKLKERKEKEEQRRIAAEEKRHQKDEAQKEKFTAILYRTLERRRLADDYQQKRWSWGGSAMANSESKTANKRSA-------STEKLEQGTSALIRQMPLSSAGLQNSVAKRKTDKERSSSLNRRDSNLHSSTDKEQAERKPR---------------------------------------------------VTGVTNYVMQYVTVPLRKCTSDELRAVMFPMSTMKIPPQTKVEE---------------------------------SPLEKVETPPKASVDAPPQVN-VEVFCNTSMEASPKAGVGMAPEVSTDSFPVVSVDVSPVV-----------------------------------------STYDSEMSMDASPELSIEALPKV-----------------------------------------------------------------DLETVPKVSIVASP------EASLEAPP-------------EVSLEALPEVSVEAAPEGSLEAPPKGSAE---------------VAPKESVK-GSPKESMEASPEAMVKASPKTSLEASMEASPKAKARDAPKKSEMDKQ----ALIPIAKKRLSSYTECYKWSSSPENACGLPSPISTNRQIQKNCPPSPLPLIS----------------KQSPQTSFPYKIMPIQHTLSVQSASSTVKKKKETVSKTTNRCEALSQRHMIYEESGNKSTAGIMNAEAATKILTELRRLAREQ-REKEEEERQREEMQQRVIKK-------SKDMAKEAVGGQAEDHLKLKDGQQQNETKKKKGWLDQEDQEAPLQKGD-AKIKAQ------EEADKRKKEHERIMLQNLQERLERKKRIEEIMKRTRKTDVNASKVTETSSHDIYEEAEADNEESDKDSLNEMFPSAILNGTGSPTKFKMPFNNAKKMTHKLVFLEDGTSQVRKEPKTYFNGDLKNFRQKSMKDTSIQEVVSRPSSKRMTSHTTKTRKADETNTTSRSSAQTKSEGFHDILPKSSDTFRQ--------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QLL1-1", "uniprot_id": "A0A8M1QLL1_DANRE", "id": "A0A8M1QLL1-1", "name": "", "aln": "-------------------------------------------------------------MAEGATSLKGLRAQMAAAAQAQAEERRSQAGNSPTPAAPANTTKSQTKPVIDGASLRIDDKLRVAKERRE------EQEKQ-HAARETQLLERERKSRLQVERQMEERHKKLEEQRRKEEQRRAAVEEKRKQKLEEEKEHYEAVMRRTLERSQRVEQRQ-KRWSWSGLADSDNKN-----------------------------------------------DKRSSSTTNLKQTDSVISKRLSSS-------------------------------------------------------------------------------SATLLNSPDKTRRSLAAPVDS---------------------------------GVLSRLLTPTQASLARSKSAAALSAEGGDAQESHLCPRSASASPMQPSARGPLRSRSSDRK-----------------------------------------KGPTTSVSADAISSMTQQKGEKE-----------------------------------------------------------------KRFTSP-----------------VGKRP-------------ASPSNRHRSPSPAPSASSTARAPSPGAAK---------------QSPRVRPPSPSGLKQRPPSPQPSATSKPPPIQKAALTPTG---------------------------------PPTLRKRDSKPKDMTPMMPVAP--SSPETSTPSPVPAPA----------------PKTKEESNSKAIAGTN---SAAEASKILAENRRLARE-----------------------------QKEKEEQLRIQKEEEEKLRKEEEKRLAEEERLRRAEEE-------KRLAEERKREEEEQTRLAEEE-------KQQMELEEQQRQAEQQKEREEAEAKAQ------EEAERQRQERARIMQQNQQERMERKKRIEEIMKR----------TRKTDQMDFKSDDVDGIPDEDGEGAEDQINCENKENEAVESECCG------EQTEEHHFPLKETDSDREETAVDINSQTHADNKENSNGPSTQDPLVDSPPPKSCLMEGSEFLNEDSKVNLVPGLNGKGG---PWSFEELIDLGVHAKTKPLMDDGSPEGPRVAFEEKTSSIHPAQPIEALSEM-----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JNK1-1", "uniprot_id": "A8JNK1_DROME", "id": "A8JNK1-1", "name": "", "aln": "------------------------------------------------------MASLGGQHGNISTNPEVENTAKRPESREGSAERKAHAFAPAKISGCSAGATLHWFAQVGGQISASEDDSQASKDREEKLKYARDRQNEERHRKIEELRAQAEAAQRYREQKEEERRRRIEEIRTRDTEKRHQVEERKKAIFEAEKERREYILKKNQERESRIEVKKRDRNSIGFAFGSSTPRLLDVPADYGLVSPSAFWGQRRSTSISNVAGASLTRRSSERELADSGAKKRASSSTDRQDDHRRKSSSMYEVFNWGYSNDEPPKRFSLSIAGSEINIDGPANPHPPPTSKQTANAHRPTNLTTTTATSTTTAGHNNFNNNNSYRKEDSVDSSPMVFRSVYRRKTDLMPTIPSPRDGHYGSRGSLSSTPARTPGRAYSMNRLDQLAQPIRRNGEHMRAILERERRERELEMLDETASLGGGGGRRGAGSSARARRAGSAGSGSSSAAGIMSRSMTHLAGGGGQRERGKYSLGGGISTSFRPLASGAGGQRDSTSKSMTQISSWSVYGSTAPQQPPPNHLHHLRQSTLGLQTAATKKYLQSSFASASSFNSASFRANATGRGRQQQYAISTNPHRFLDLDPNSLLLMNSASLLVNAGSRSGNATPGGHFNNSRPGSAMSTSTNMSTSGLVPRRPATAPRKPRPASIAGTGMSLEEINKLKRDQKPPVKTTAASPSAQTTPKRTANLMSTSLIVTSSSSRLSSAEKKTPSKREPPVPKAASASKALPSRTASSERISRLTKEPKTKDTSAMTRSMIVTSSSTSTITKPAPAPVAPTSAPVPEQNGVAKEVEKTTADEPVPEAEVPTEAPVVVPSVSKAEKEALNTEKTEEGARQEEEQILAVESVPEALVTSINVEEKSDEGNEKEVPKPQEQAAPKKPSRSKENSEVRELTPPEGADLMTASMMAKKITTEEEAKAALAERRRLAREEAERQAELERQRLEAERLAEIKAQEEEAERQRLFEEESTRLAEEQRRGEEERLRKAIEEAQQREEEEKRRREEEEKQRVEREEAEKKAKEEAEKQRVEVAERLKREEKEREERRKRVEAIMLRTRKGGAATTPSKDANDKAAPAATAPENNSSSNSSVTGSSNNSAEGSPSAADSTPAPTATETVQEAPNSQAMYEQSVLDKENSLINSFSTMIIDENAKNLQQVSNGKLLVDFESTNTVP-AVANGNGHIENVNNKNDINLLQDVVAPVATQLIDLSIESQDLHLNNNNSLLTSTAATTTLVTADSHENKDISLL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... . . . :. : **: : : . .* : . : :::*.* ::..: : :* : . :: *:: **::::::* : :: .:: .**::: :.*: :: :. ** : : .* * .:. **: . :: : : . : : :. : :. : . * . . . . . . * . . : . * . . . : . : : .: : . . *:* * . : . . . : . . : .: : : :: .. ..* . : : . : . : : . :.. :.: : :*: :. :: :*. : : .: : : . : . : *.. ::. : . .. . .. : ", "identical_positions": 29, "similar_positions": 168, "identity": "2.24%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121130-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AA40-1", "uniprot_id": "A0A8I6AA40_RAT", "id": "A0A8I6AA40-1", "name": "", "aln": "MAAAPGEDAGEEDRPRGPGCCDCDTLTGVCPCWGGSFLPGVTALIWACLKYPGPMDLKEKHLGE-PPSALGLTTGKALSVLKEQLEAVLEKHLKERKKRLTWKEAWRSSFLHLSNRRSCFHWPGASLMLLAVLLLLCCSGGQPAGSRGVELVNASALFLLLLLNLILIGRQDRLKRQEVERRLRGIIDQIQDALR--DGKEIKWPNSMYPDLHMPFAPSWSLHWAYRDGHLVNLPVSLLVEGDIIALRPGQESFASLRGIKDDEHIVLEPGDLFPPFSPPPSPRGEVKKGPQNPQQYRLFRVLETPVIDSIRWCLDTALSRPVTALDNER-FTVQSVMLHYAVPVVLAGFLITNALR---FMFKAPGVTSWQYTLLQLQVNGMLPILPLLFPVLWVLATACGEARVLAQMSK---ASPSSLLAKFSEDTLSSYTEAVSSQEMLRCIWGHFLRVIQGTSPTLSHSASLLHSLGSVTVLCCVDKQGILSWPNPSPETVLFFSGKVEPPHSSHEDLTDDLSTRSFCHPEVEE---EPHERDALLAGSLNNTLHLSNEQERGDWPGDGPKPSEPYSHHKG--HGRSKHPSGSNVSFSRDTEGGEEEPSKAQPGTEGDPYEAEDFVCDYHLEMLSLSQDQQNPSCIQFDDSNWQLHLTSLKPLGLNVLLNLCNASVTERLCRFSDHLCNIALQESHSAVLPVHVPWG-------------LCELARLIGFTPGAKELFKQENHLALYRLPSAETVKETS--LGRPSCVTKRRPPLSHMISLFIKDTATSTEQMLSHGSADVVVEACTDFWDGADIYPLSGSDRKKVLDFYQRACLSGYCSAFAYKPMNCTLSSQLNG------KCIELVQVPGQNSISTLCELP-------STVPIKPNIRRSSWSSDEGIG-EVLEKEDCMQALSGQIFMGMVSSQYQARLDIVRLIDGLVNACIRFVYFSLEDELRSKVFAEKMGLETGWNCHISLTPN--------------------------------------------------------------------------------------------------------GDMPGSEIPPSSPSHAGSLHDDLNQVSRDDAEG----------------------------LLLLEEEGHSDLISFQPTDSDIPSFLEDCNRAKLPRGIHQVRPHLQNIDNVPLLVPLFTDCTPDTMCEMMKIMQEYGEVTCCLGSSANLRNSCLFLQSDVSIALDPLYPSRCS----------------WESFG--------------YATSTTMAQASDGLSPLQLSGQLNSLPCSLTFRQEETISIIRLIEQARHATYGIRKCFLFLLQCQLTLVVIQFLSCLVQLPPLLSTTDILWLSCFCYPLLSISLLGKPPHSSVMSMATGKNLQSIPKKTQHYFLLCFLLKFSLTISSCLACFGFTLQSFCDSAR----ARNLTNCSSVMLCSNDDRAPAWFEDFANGLLSAQKLTAALIVLHTVFISITHVHRTKPLWRKSPLTNLWWAVTVPVVLLGQVVQTVVDLQLWTHRDSPVHFGLEDVPLLTWLLGCLSLVLVVVTNEIVKLHEIRVRVRYQKRQKLQFETKLGMNSPF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TSH8-1", "uniprot_id": "TMM94_MOUSE", "id": "Q7TSH8-1", "name": "Transmembrane protein 94", "aln": "------------------------------------------------------MDLREKHLGE-PPLALGLSTRKALSVLKEQLEAVLEKHLKERKKSLTWKEAWRSSFLHLSNRCSCFHWPGASLMLLAVLLLLCCCGGQPAGSQGVELVNASALFLLLLLNLVLIGRQDRLKRREVERRLRGIIDQIQDALR--DGKEIKWPNSMYPDLHMPFAPSWSLHWAYRDGHLVNLPVSLLVEGDIIALRPGQESFASLRGIKDDEHIVLEPGDLFPPFSPPPSPRGEVKRGPQNPQQHRLFRVLETPVIDNIRWCLDTALSRPVTALDNER-FTVQSVMLHYAVPVVLAGFLITNALR---FMFKAPGVTSWQYTLLQLQVNGMLPILPLLFPVLWVLATACGEARVLAQMSK---ASPSSLLAKFSEDTLSSYTEAVSSQEMLRCIWGHFLRVIQGTSPTLSHSASLLHSLGSVTVLCCVDKQGILSWPNPSPETVLFFSGKVEPPHSSHEDLTDDLSTRSFCHPEVEE---EPHEHDALLAGSLNNTLHLSNEQERSDWLADGPKPSEPYPHHKG--HGRSKHPSGSNVSFSRDTEGGEEEPSKAQPGTEGDPYEAEDFVCDYHLEMLSLSQDQQNPSCIQFDDSNWQSHLTSLKPLGLNVLLNLCNASVTERLCRFSDHLCNIALQESHSAVLPVHVPWG-------------LCELARLIGFTPGAKELFKQENHLALYRLPSAETLKETS--LGRPSCVTKRRPPLSHMISLFIKDTATSTEQMLSHGSADVVVEACTDFWDGADIYPLSGSDRKKVLDFYQRACLSGYCSAFAYKPMNCTLSSQLNG------KCIELVQVPGQNSIFTMCELP-------STIPIKPNNRRSSWSSDEGIG-EVLEKEDCMQALSGQIFMGMVSSQYQARLDIVRLIDGLVNACIRFVYFSLEDELRSKVFAEKMGLETGWNCHISLTPN--------------------------------------------------------------------------------------------------------GDMPGSEIPPSSPSHAGSLHDDLNQVSRDDAEG----------------------------LLLLEEEGHSDLISFQPTDSDIPSFLEDCNRAKLPRGIHQVRPHLQNIDNVPLLVPLFTDCTPDTMCEMIKIMQEYGEVTCCLGSSANLRNSCLFLQSDVSIALDPLYPSRCS----------------WETFG--------------YATSTTMAQASDGLSPLQLSGQLNSLPCSLTFRQEESISIIRLIEQARHATYGIRKCFLFLLQCQLTLVVIQFLSCLVQLPPLLSTTDILWLSCFCYPLLSISLLGKPPHSSIMSMATGKNLQSIPKKTQHYFLLCFLLKFSLTISSCLVCFGFTLQSFCDSAR----ARNLTNCSSVMLCSNDDRAPAWFEDFANGLLSAQKLTAALIVLHTVFISITHVHRTKPLWRKSPLTNLWWAVTVPVVLLGQVVQTVVDLQLWTHRDSRVHFGLEDVPLLTWLLGCLSLVLVVVTNEIVKLHEIRVRVRYQKRQKLQFETKLGMNSPF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12767-1", "uniprot_id": "TMM94_HUMAN", "id": "Q12767-1", "name": "Transmembrane protein 94", "aln": "------------------------------------------------------MDLKEKHLGE-PPSALGLSTRKALSVLKEQLEAVLEGHLRERKKCLTWKEVWRSSFLHHSNRCSCFHWPGASLMLLAVLLLLGCCGGQPAGSRGVGLVNASALFLLLLLNLVLIGRQDRLKRREVERRLRGIIDQIQDALR--DGREIQWPSAMYPDLHMPFAPSWSLHWAYRDGHLVNLPVSLLVEGDIIALRPGQESFASLRGIKDDEHIVLEPGDLFPPFSPPPSPRGEVERGPQSPQQHRLFRVLETPVIDNIRWCLDMALSRPVTALDNER-FTVQSVMLHYAVPVVLAGFLITNALR---FIFSAPGVTSWQYTLLQLQVNGVLPILPLLFPVLWVLATACGEARVLAQMSK---ASPSSLLAKFSEDTLSSYTEAVSSQEMLRCIWGHFLRVLGGTSPTLSHSSSLLHSLGSVTVLCCVDKQGILSWPNPSPETVLFFSGKVEPPHSSHEDLTDGLSTRSFCHP-------EPHERDALLAGSLNNTLHLSNEQERGDWPGEAPKPPEPYSHHKA--HGRSKHPSGSNVSFSRDTEGGEEEPSKTQPGMESDPYEAEDFVCDYHLEMLSLSQDQQNPSCIQFDDSNWQLHLTSLKPLGLNVLLNLCDASVTERLCRFSDHLCNIALQESHSAVLPVHVPWG-------------LCELARLIGFTPGAKELFKQENHLALYRLPSAETMKETS--LGRLSCVTKRRPPLSHMISLFIKDTTTSTEQMLSHGTADVVLEACTDFWDGADIYPLSGSDRKKVLDFYQRACLSGYCSAFAYKPMNCALSSQLNG------KCIELVQVPGQSSIFTMCELP-------STIPIKQNARRSSWSSDEGIG-EVLEKEDCMQALSGQIFMGMVSSQYQARLDIVRLIDGLVNACIRFVYFSLEDELKSKVFAEKMGLETGWNCHISLTPN--------------------------------------------------------------------------------------------------------GDMPGSEIPPSSPSHAGSLHDDLNQVSRDDAEG----------------------------LLLMEEEGHSDLISFQPTDSDIPSFLEDSNRAKLPRGIHQVRPHLQNIDNVPLLVPLFTDCTPETMCEMIKIMQEYGEVTCCLGSSANLRNSCLFLQSDISIALDPLYPSRCS----------------WETFG--------------YATSISMAQASDGLSPLQLSGQLNSLPCSLTFRQEETISIIRLIEQARHATYGIRKCFLFLLQCQLTLVVIQFLSCLVQLPPLLSTTDILWLSCFCYPLLSISLLGKPPHSSIMSMATGKNLQSIPKKTQHYFLLCFLLKFSLTISSCLICFGFTLQSFCDSSR----DRNLTNCSSVMLPSNDDRAPAWFEDFANGLLSAQKLTAALIVLHTVFISITHVHRTKPLWRKSPLTNLWWAVTVPVVLLGQVVQTAVDLQLWTHRDSHVHFGLEDVPLLTWLLGCLSLVLVVVTNEIVKLHEIRVRVRYQKRQKLQFETKLGMNSPF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QJ95-1", "uniprot_id": "A0A8M9QJ95_DANRE", "id": "A0A8M9QJ95-1", "name": "", "aln": "------------------------------------------------------MELQDKKQEEETATPLGLSTAQALCTLRDQLSNLLGQHQKFSRRRPTIQELWAKSFLHHGDRHSCFHWPGAVLTLVVVVGLLSCHGSQPEGSQGIELVNAGALFLLLLLNLFLIGRQQRLRISEMVRRLKSIISQLNDYLERSAGHPIRWAPSLYPDLYTPTSPSWSLHWTFRDEQLVNLPVSLLVEGDVIALRPGQEAFASLRGIKDDEHIVLEPGDLFPPFSPPPSPRGNERRGPHSPQQYRLFRVVRTPILDSVRNSLDLALSRPITALDNER-FTVQSIIAKFACPAVLVAFFSMNTIR---YFCDTPGLTPGPFNFLQLQMMGVLPILPLLFPVMWVLVNAYGEARVLAESSR---NSPTGLLAKFSEDTLSSYTEVVSSQEMLRCVWRHLVSVLKGESQTLCYTSSLLHTLGSVTVLCCVDKQGILSWPNPSPETVLFFSGRVEPPHDSQDDLRDDLSVNSLCRTEGEEDRDEPQEGEALLCLPAFEPPLHMAEQEPSETSHDTARSSDTQRQRRGPQTTRSKHPSGSNVSFSHDTEGGEND-FVQQCGLGDDLCEADDFVCDYHLEMLSLSQDQQNPVSIQFDDSGWQNHLSSLKPLGLNILLNLCNATVTQQLCRFSDHLSNLALQECHGAVLPVHVPWG-------------LCELSRLIGFTPGARELFKHENHLALYQLPSGEKAKESA--PRRLHHFTKRQPPISHLISLFVRDNTTNNVQMLSHGSADLILEACTDFWDGADIYPLSGSDRKKVLDFYQRACLSGYCSAFAYKPMQVTLSGQLNG------KCVELAPGP---ALFSGVELP-------STTPIKHGSRRNSWSSDEGIG-EGLEKEDCVQALSGQIFMGMVSSQFQARLDTVRLIENLVGACIRFVYFSMEDELRSKVFAEKMGLETGWNCHISLTPN--------------------------------------------------------------------------------------------------------GDG-HCDGAPSSPSQAGSLHDELLQDSRDDAEG----------------------------PLLPEDQ--SDLASFQPTDSDVPSFLEDCNRAKLPRGIHQVRPHLKNIDNVPLLVPLFTDCTPETMCEMMKIMQENREVTCCLGSSANFRNSCLFLQSDISISLDPLYPSRCS----------------WETFG--------------YAAVCGLNEECDELSPLGLSASLNSLACSVSFHQGESVSMVKLIEQARHTTYGIRKCFLFLLQCQLTLVIIQFLACLIQLPPPMNITDILWLSCFCYPLLSVSLLGKPPDSSVMTVATGKNLDSIPRKTQHYFLGWFLLKFGLTVLAYLVGFGFSLQEVCSRAANFTKTDNSTINCSHILTSSSQGAPEWFGELSNGLLLIQKIMAGFLALHTVVISFSYVHRSQPLWRRNPFSNTWWCLTVPVVLLGQVVQAVIDYHLWRNRRTEVVFTLHHIPLMVWLLVSLSIVLVVLINEAVKLHEIRVRVRYQKRQKLQFETKLGMNSPF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQZ1-1", "uniprot_id": "Q9VQZ1_DROME", "id": "Q9VQZ1-1", "name": "", "aln": "--------------------------------------------------MAAKRAESPEKRASPEPTLRGLTTKVALRRLHEEIEKRVQLEHERQYGAESPYRKLRAAFVKRYDSP--LGWLSIGSSLLASGALLATG----------MLWPALCLLAILSLDLFVVVRENNLRRTEIFRKARHAISEIKLAEQ---HFSDDWQQSNYPHLSNPMSPCVSLQWTYRDGKIVNLPWALLVRGDYIVLRPGHISPGPCHELETNKFFAANEIYGAAPHGDPP-----VKPVARPPLPNLVCCLESTPYLDNLTVCLKNSLKRPPTIYNQQRYLLVTKYIQQWGFISALVITLISGLLRLHGYGLPTDEKHNWRFVLVESSAAAIVPLLPLIFPLMWISMNLWGIARLQCFLKTPQAALEKSTSKSFEEDLDTPSYDYQNMSMLRSSVLRIWMQLWRGDSELLPRSANLVQVLGSISALCCVDKKGILSWPNPTAEKVFFLHNTDEEAREDG-----------------------------------------AGSQSSSQSESDDVPVVDEDHKERG-----------------------------------------------IVAEVLDLTHDQHCPFRLEFDDHEWKAHIKSLKPLGLAILLNTCSPLTHEHYAQFCGHVTAVAMLDKDLVPVTNRYAYALIESSKSFLHGRCLCELAKQIGFTDHATDRFALEGQLASYRHLQPDVVRRDIRFARQLQLSSKVKVPFPHSLSVVMRENPGGYLSLFTQGTADIILDCCDDFWDGIDLRPLSAQDRKRALDFYQRSALTSYCTAFAYRPLRHGIHGALSGPQRSGGDCLYLELPPESKLRMQHVDKTHCDFQGGHHVKLSHSISTDSLLFSENKDEECNDVEGCFEMQCHQVFIGMVTMQYQAQNDIVRLVEHLEQACIRFVHFSKENELRSRVFSEKMGLESGWNCHISLLSEPEPDSEKERISAKPKEFPENIGKPQATTSTTATTTTTDHENNHHPSAKVMYISPPAPAPATASVSESISAAKTTEIVGDGPEISYLLGPPNNLESSKTLSSSAPGAISNPDENPLNALNSGDSHSPDSEGSKESSQDSCTKNNPPGDSELEAETEANKHKQRHSLDSAMDENCRSLSTLTESTDQSAPINFDMSNRAKLPRGIENIRPHLEQVDNVPLQVSLFTDCSAEATRQMLDIMQSYGEIVVCLGSSASNANADIFLQADCSIAVEPLYPQVCQDVDAYTEANIQNNKLLWQRHSGKSKGNDDEELLEGGLHGCAMQSPAHTISPLYLSRLLNSLPCSIAVCRDDPLSLVAIIELSRRFSLGLWNCIQYWACCAGSISILNVLCACLSQPPLVTPLLGIYLMCVPVPLIAISLAHIDVDPKIMNRATSKKQTDYDSRAFAFVMWCYGCKFIVLVVSLLVSYWMLLPNTQLNPA-------EPATEEPVLEIDDDDDPEFYQFLY----IARSSALLGIILHFVFISVTFVHRDHALWQRNPFTNRIWAFTCLFLVLIHGIICFVQLLLED------FWVQLPNQWLALLILFGGSLLSMLVSELAKFQENKVNARYQRRARLDFGTKLGMNSPF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . . **:* ** *::::. : . . : . :*:: : : * . *:. ** * * .*: :* *:*.:: *::.*: *: *: : *.::: . * : **.* * :*. **:*::** ::**** :***.** *.****: : .. : :: ::.:. : .*.. ** . .: * : : ** :*.: .*. :*.** * :::* : * . : ::. .*. : . :* : : : ::: . .::*:***:**::*: . * **: . . .. .*.** :. : . . : .: : : * * * ::.*:: ***::.******:********:.*.*:*: . * .:.. .*. .: : : :.:. *:*.*::**: * ::*** *: *:.******* :*** *.. . :: .:*..*: :*: : . . :. : .:. ****:: **** * : * *.:** *: . : :. : :* : *:.* :*:.:::.. . .::::*:**::::.* ***** *: ***..***:.******:.*:.**:****:*:. : . *.* .*: * * : . :. . .* .*. . * : *.*.: . *:*:***: *:**: * ***:: * ******:** *:**:*:**:******:******** .: * : * .. ::*. *. : *::.::. ::: * :.**.. * :: .*********.::****:::***** *.*****:.:: :*:.***. *:. ******. *: :***:* **:::****. *. *: .. : . .. :*** ** ****.**::. : :.:*:: :** :*: : *: :*: : * :: :::.*.. :. ** :. ::* *. **:::** ...:*. **.*: . :: :.: : ** : : : * : : * . . . . :* ..: * :: : :. : ** *.**.:.*** :.**::.*::* *..* .::* : : :: * : :. *: . :* :: .* .*::* :*..***:* :*:* *********", "identical_positions": 357, "similar_positions": 437, "identity": "21.98%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121130-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UY90-1", "uniprot_id": "GAK1A_MOUSE", "id": "Q3UY90-1", "name": "Golgi-associated kinase 1A", "aln": "MVSWIWRRLRGKKRSVMAFCLLMVLSAVAVIHFPPGHP----ASTPGLNPMEPRGEVGASDPRIQQTLN------SSLRQPARNLGHWTGQALPRNPILVCAKKQSRRRQVDRSR--------HPLSVRRDAILSAQDRE------LLLEGEVRDAGGAALGQPGHNGLVQETQSKTVTMVVPLTERSHESFQAQRDTAAASFRPWPADGRDPLPGAKNGVLTGG-KAGSATSGSEAPWWSSSAEDLQKSPWCGTETPGLAGTAAWGQVPPWFMEHDAQTLRLLVHGKVVGKARVPAHGQVLQVGLSAGDALQDISPLRLSQFCSQGLCGLIKRSKDLHEVLSFHLDRVLGLQRSLPAVARSFHSPLLPYRYTDGSVRPIIWWAPDVQHLRDPDEDQNSLALGWLQYQALLARGCKWPG---QIPCLGIHHAEWARLALFDFLLQVHDRLDRYCCGFEPEPSDPCVEEGLREKCRNPEELRLVHILVRSSDPSRLVYIDNAGNLQHPEDKLNFRLLEGIDGFPESAVKVLASGCLQNLLFKSLQMDQVFWESQGGAAGLKHVLETLESRGQILLRHIKKHNLTLFRDKDP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UFP1-1", "uniprot_id": "GAK1A_HUMAN", "id": "Q9UFP1-1", "name": "Golgi-associated kinase 1A", "aln": "MASWLRRKLRGKRRPVIAFCLLMILSAMAVTRFPPQRP----SAGPDPGPMEPQGVTGAPATHIRQALS------SSRRQRARNMGFWRSRALPRNSILVCAEEQGHRARVDRSRESPGGDLRHPGRVRRDITLSGHPRLSTQHVVLLREDEVGDPGTKDLGHPQHGSPIQETQSEVVTLVSPLPGSDMAALPAWRATSGLTLWPHTAEGRD-LLGAENRALTGGQQAEDPTLASGAHQWPGSVEKLQGSVWCDAETL-LSSSRTGGQAPPWLTDHDVQMLRLLAQGEVVDKARVPAHGQVLQVGFSTEAALQDLSSPRLSQLCSQGLCGLIKRPGDLPEVLSFHVDRVLGLRRSLPAVARRFHSPLLPYRYTDGGARPVIWWAPDVQHLSDPDEDQNSLALGWLQYQALLAHSCNWPG---QAPCPGIHHTEWARLALFDFLLQVHDRLDRYCCGFEPEPSDPCVEERLREKCQNPAELRLVHILVRSSDPSHLVYIDNAGNLQHPEDKLNFRLLEGIDGFPESAVKVLASGCLQNMLLKSLQMDPVFWESQGGAQGLKQVLQTLEQRGQVLLGHIQKHNLTLFRDEDP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F233-1", "uniprot_id": "E7F233_DANRE", "id": "E7F233-1", "name": "", "aln": "MALRLCMKLRLKCRFVVAFLFLFSLSVAIIYTLPPFQSEQIRANVRGPRNNKPSKLLEKWSLRPYKKLPGKSLKNPEMKDSAKHLLMFSHFHQTFSSGKIAEGKASTKKPSSKQYMKNPN--KHPIKSFRGSAKRAQAVR--------LRNSSSSNTTIHLLRSRHDQAFPHSAS--IRSLRPNNKTCRHKCTPDGDKVERIVGHFSDAQQVVKLKQAPREAGAHERQAGPSERKRPKFKTEREAEAGISDWC--KTLNESWNQTKAESLPWFSADDIKKMALLSRGTVVSKARLPGHGQVLQVGLS--DKNDTFASAGHLKRCQKESCALIKRPNDWSEVFAFHLDRVLGLNRSLPAVLRAFHSEILPYKYTSGSPRPVVWWDPSIQHLSDAENDQNSFSLTWPEYQALLKSRCGIQVPLNFTTCVGVHHSEWGRLALFDFLLQVNDRLDRSCCGFRADPSDLCIENLLHVKCGNPKDLNLVHILVRKTEPSKLVFIDNAGRPHQPHDNLNFRLVEGIDEFPEKAVSVLQSGCLEKMLLHSLSVDQEFWLSREEASGLKSLIQHTEQRAKALLRHIQEKNLRLNRDL--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : :** * * *:** :*: **. : :** :. : . :* : : * .. :: *::: : . .. :. : . : .:. ** *. .: ... . * :. *. . .: * : : * . . . . : . : ..: . . . . * ** :* : . : .: **: .* : : ** :* **.***:*.********:* : ::. : *.: *.****. * **::**:******.****** * *** :***:**.*. **::** *.:*** *.::****::* * :***** * .* *:**:**.***********:***** ****..:*** *:*: *: ** ** :*.*******.::**:**:*****. ::*.*:*****:**** ***.**.** ****:::*::**.:* ** *: * *** ::: *.*.: ** **:::** * ** ", "identical_positions": 199, "similar_positions": 149, "identity": "33.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121204-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61508-1", "uniprot_id": "ECM1_MOUSE", "id": "Q61508-1", "name": "Extracellular matrix protein 1", "aln": "MGTVSRAALILACLALASAASEGAFKASDQREMTPERLFQHLHEVGYAAPPSPPQTRRLRVDHSVTSLHDPPLFEEQREVQPPSSPEDIPVYEEDWPTFLNPNVDKAGPAVPQEAIPLQKEQPPPQVHIEQKEIDPPAQPQEEIVQKEVKPHTLAGQLPPEPRTWNPARHCQQGR-RGVWGHRLDGFPPGRPSPDNLKQICLPERQHVIYGPWNLPQTGYSHLSRQGETLNVLETGYSRCCR---CRSDTNRLDCLKLVWEDAMTQFCEAEFSVKTRPHLCCRLRGEERFSCFQKEAPRPDYLLRPCPVHQNGMSSGPQLPFPPGLPTPDNVKNICLLRRFRAVPRNLPATDAIQRQLQALTRLETEFQRCCRQGHNHTCTWKAWEGTLDGYCERELAIKTHPHSCCHYPPSPARDECFAHLAPYPNYDRDILTLDLSRVTPNLMGQLCGSGRVLSKHKQIPGLIQNMTIRCCELPYPEQACCGEEEKLAFIENLCGPRRNSWKDPALCCDLSPEDKQINCFNTNYLRNVALVAGDTGNATGLGEQGPTRGTDANPAPGSKEE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16610-1", "uniprot_id": "ECM1_HUMAN", "id": "Q16610-1", "name": "Extracellular matrix protein 1", "aln": "MGTTARAALVLTYLAVASAASEGGFTATGQRQLRPE----HFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPP-FEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELP------------SLQHPNE---QKEGTPAPFGDQSHPEPESWNAAQHCQQDRSQGGWGHRLDGFPPGRPSPDNLNQICLPNRQHVVYGPWNLPQSSYSHLTRQGETLNFLEIGYSRCCH---CRSHTNRLECAKLVWEEAMSRFCEAEFSVKTRPHWCCTRQGEARFSCFQEEAPQPHYQLRACPSHQPDISSGLELPFPPGVPTLDNIKNICHLRRFRSVPRNLPATDPLQRELLALIQLEREFQRCCRQGNNHTCTWKAWEDTLDKYCDREYAVKTHHHLCCRHPPSPTRDECFARRAPYPNYDRDILTIDIGRVTPNLMGHLCGNQRVLTKHKHIPGLIHNMTARCCDLPFPEQACCAEEEKLTFINDLCGPRRNIWRDPALCCYLSPGDEQVNCFNINYLRNVALVSGDTENAKGQGEQGSTGGTNISSTSEPKEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IMZ6-1", "uniprot_id": "A0A0R4IMZ6_DANRE", "id": "A0A0R4IMZ6-1", "name": "", "aln": "---------MVWKSTLLSAVILHLFSSGAGQNMDPD-----------------VLMDSI-------------------------------------------------------------------------------------------------------------------------------FPPARPSLYNLNSLCLHGNGRFRYTAESFPPSSFAHARRAGKTMNRLEAWFGQCCYGGLAHKNGQILCCAKQAWETALSYFCLEEFSTKTLVHDCCEKKGGERWGCFEREAPNPYYQPLPG-YIAPQISSDRIFTWDP---------KAC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :: **. *.: ::: *: : ***.*** **:.:** . :. * . .:* :.::* * *:*:* ** :.:** .:.. : * * * .** *:: ** ***.** * ** :* *:.**:.***.* * . :**. :.: * : * ", "identical_positions": 54, "similar_positions": 53, "identity": "9.59%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121204-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61508-1", "uniprot_id": "ECM1_MOUSE", "id": "Q61508-1", "name": "Extracellular matrix protein 1", "aln": "MGTVSRAALILACLALASAASEGAFKASDQREMTPERLFQHLHEVGYAAPPSPPQTRRLRVDHSVTSLHDPPLFEEQREVQPPSSPEDIPVYEEDWPTFLNPNVDKAGPAVPQEAIPLQKEQPPPQVHIEQKEIDPPAQPQEEIVQKEVKPHTLAGQLPPEPRTWNPARHCQQGR-RGVWGHRLDGFPPGRPSPDNLKQICLPERQHVIYGPWNLPQTGYSHLSRQGETLNVLETGYSRCCRCR-SDTNRLDCLKLVWEDAMTQFCEAEFSVKTRPHLCCRLRGEERFSCFQKEAPRPDYLLR--------------------------PCPVHQNGMSSGPQLPFPPGLPTPDNVKNICLLRRFR--AVPRNLPATDA--IQRQLQALTRLETEFQRCCRQGH-NHTCTWKAWEGTLDGYCERELAIKTHPHSCCHYPPSPARDECFAHLAPYPNYDRDILTLDLSRVTPNLMGQLCGSGRVLSKHKQIPGLIQNMTIRCCELPYPEQACCGEEEKLAFIENLCGPRRNSWKDPALCCDLSPEDKQINCFNTNYLRNVALVAGDTGNATGLGEQGPTRGTDANPAPGSKEE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16610-1", "uniprot_id": "ECM1_HUMAN", "id": "Q16610-1", "name": "Extracellular matrix protein 1", "aln": "MGTTARAALVLTYLAVASAASEGGFTATGQRQLRPE----HFQEVGYAAPPSPPLSRSLPMDHPDSSQHGPP-FEGQSQVQPPPSQEATPLQQEKLLPAQLPAEKEVGPPLPQEAVPLQKELP------------SLQHPNE---QKEGTPAPFGDQSHPEPESWNAAQHCQQDRSQGGWGHRLDGFPPGRPSPDNLNQICLPNRQHVVYGPWNLPQSSYSHLTRQGETLNFLEIGYSRCCHCR-SHTNRLECAKLVWEEAMSRFCEAEFSVKTRPHWCCTRQGEARFSCFQEEAPQPHYQLR--------------------------ACPSHQPDISSGLELPFPPGVPTLDNIKNICHLRRFR--SVPRNLPATDP--LQRELLALIQLEREFQRCCRQGN-NHTCTWKAWEDTLDKYCDREYAVKTHHHLCCRHPPSPTRDECFARRAPYPNYDRDILTIDIGRVTPNLMGHLCGNQRVLTKHKHIPGLIHNMTARCCDLPFPEQACCAEEEKLTFINDLCGPRRNIWRDPALCCYLSPGDEQVNCFNINYLRNVALVSGDTENAKGQGEQGSTGGTNISSTSEPKEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7D9-1", "uniprot_id": "A0ACD6B7D9_DANRE", "id": "A0ACD6B7D9-1", "name": "", "aln": "-MSSPRGVGLYLTLLFALLCDASEDSSLLQRDITDMLVDEVADGHQKESPLSPEEIEFLMMQRPVLPDFSKVMVAGSSDMTQREVTN------------FHPENVPIGPPV-------------------------------------FGPRSAGPRTGPEVD-----------------------FPPAFPNTGNLQDICRFSKAPVRYPKDMFPSSGFGNVARQGEAVNQLQSWYGVCCGINGTQEEQICCAEQAWKKSLSAYCSQEFTIKTSHFFCCKKNGRARWSCFDKEASDSSYQVSSEISNGNASQKFKGFKYNSSACKGSLASPKALKKQTAAPDLTFPPGRPESSNIANICAHRKIRPRYITSCLPHTGYGWLVRQSKTINVLEREYNRCCKEKKGVQRCAEQKWKKMVDKFCKDEKKSKRQQFECCEKKKREEQYACFTSAAPDPGYSSTDGQLSSTAAPPTLH-TFCDVHTAIQSMKGFPFSLDNMAERCCLLAAQERPACIEAELGSHLNDMCKTKEPVKHH----CCASEIKNHVKCATKLLLRHIGKANKVKESGRKKCPLNI---------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .*.. : * .* .. . .: **:: . :* ** . * :::. . .. . . :: : * **.: * . . : ** ***. *...**::** .: * * :*.:.:.:::****::* *: *. ** . :. ::: * : .*:.::: :*. **::** . ** .*. *:***::**. . * : ..* ::. :*.**** * .*: *** *::* :. ** *. : *: :: ** *::***:: : : *: : *: :* :*. * * : . **. : **: ** *.*. :. ..*.* :*. .: . * :* :.**: *** *. *:..* * * :.::::* .:. :. * * .::::* . **::. . . .. . ", "identical_positions": 110, "similar_positions": 160, "identity": "18.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121205-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y2C3-1", "uniprot_id": "A0A8I5Y2C3_RAT", "id": "A0A8I5Y2C3-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDFSSVVCLPPSVIAVNGLDGGGAGENDEEPVLLSLSAAPSPQSEAVANELQELSLQPELTLGLHPGRN--------------------------------------PNLPPLSERKNVLQLKLQQRRTREELVSQGIMPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEET--SAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEALIVGQVNYPKVAD-----------SSSFDEDSS--------------DALSPEQPASHES-QGSVPSPLESRASDLLPSATSISPTQ--------------------------------------------------QSQPKSAS--------------------------------------------------EKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDKG---APAMDSSYAKILQQQQLFLQLQILNQQQQQQQQQHYNYQAILPAPP-------------KPSGETPGSSAPTPSRSLSTS-SSSSSG------------TPGPGGLARQNSTALAGKP---------------------------------GALPAN------------------LDDMKVAELKQELKLRSLPVSGTKTELIERLRAYQDQVSPAPGAPKAPATTS-------------------------------------------------------------------------------------------------VLSKAGEVVVAFPAALLSTGSALVTAGLAPAEMVVATVTSNG--------------------MVKFGSTGSTPPVSPTPSERSLLSTG-DENSTPGDAFGEMVTSPLTQLTLQASPLQIVK-EEGARAASCCLSPGARAELEGLDKDQMLQEKDKQIEELTRMLQQKQQLVELLRLQLEQQKRAQQPAPASS----PVKRESSFSSCQLSCQPQGAARAFGPGLVVPTTNH---GDAQAPAPESPPVVVKQEAGPPEPDLAPASQLLLGSQGT-------SFLKKVSPPTLVTDSTGTHLILTVTNKSADGPG--------LPTGSPQQPLSQPGSPAPGPPAQMDLEHPPQP-------------------------------SFATPTSLLKKEPPGYEETVTQQPKQQENGS--SSQHMDDLFDILIQSGEISADFKEPPS-----------LPGKEKSPP-AEAYGPPLTPQPSPL---------------------------------------------------------------SELPQAAPPP-GSPTLPGR------------------------LEDFLESSTGLPLLTSGHEGPEPLSLIDDLHSQMLSSSAILDHPPSP----------------------------------------------MDTSELHFAPEPSSGMGLDLAVGHLDSMDWLEL---SSGGPVLSLAPLSTTAP------------------SLFSMDFLDGHDLQLHWDSCL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K4J6-1", "uniprot_id": "MRTFA_MOUSE", "id": "Q8K4J6-1", "name": "Myocardin-related transcription factor A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLLEPEMLM---------------------------------------------------MAVQSVLQLKLQQRRTREELVSQGIMPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERAELVRMHILEET--SAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVAD-----------SSSFDEDSS--------------DALSPEQPASHES-QGSVPSPLESRVSDPLPSATSISPTQVLSQLPMAPDPGETLFLAEQPPLPPAPLLPPSLANGSIVPTAKPAPTLIKQSQPKSAS--------------------------------------------------EKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDKG---APAMDSSYAKILQQQQLFLQLQILNQQQQQQQQQHYNYQAILPAPP-------------KPSAETPGSSAPTPSRSLSTS-SSPSSG------------TPGPSGLARQSSTALAAKP---------------------------------GALPAN------------------LDDMKVAELKQELKLRSLPVSGTKTELIERLRAYQDQVSPAPGAPKAPATTS-------------------------------------------------------------------------------------------------VLSKAGEVVVAFPAALLSTGSALVTAGLAPAEMVVATVTSNG--------------------MVKFGSTGSTPPVSPTPSERSLLSTG-DENSTPGDAFGEMVTSPLTQLTLQASPLQIVK-EEGARAASCCLSPGARAELEGLDKDQMLQEKDKQIEELTRMLQQKQQLVELLRLQLEQQKRAQQPAPASS----PVKRESGFSSCQLSCQPQGSAHAFGSGLVVPTTNH---GDTQAPAPESPPVVVKQEAGPPEPDLAPSSQLLLGSQGT-------SFLKRVSPPTLVTDSTGTHLILTVTNKSADGPG--------LPAGSPQQPLSQPGSPAPGPPAQMDLEHPPQP-------------------------------PFATPTSLLKKEPPGYEETVTQQPKQQENGS--SSQHMDDLFDILIQSGEISADFKEPPS-----------LPGKEKSPPAAAAYGPPLTPQPSPL---------------------------------------------------------------SELPQAAPPP-GSPTLPGR------------------------LEDFLESSTGLPLLTSGHEGPEPLSLIDDLHSQMLSSSAILDHPPSP----------------------------------------------MDTSELHFAPEPSSGMGLDLAVGHLDSMDWLEL---SSGGPVLSLAPLSTAAP------------------SLFSMDFLDGHDLQLHWDSCL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q969V6-1", "uniprot_id": "MRTFA_HUMAN", "id": "Q969V6-1", "name": "Myocardin-related transcription factor A", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPLKSPAAFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEET--SAEPSLQAKQLKLKRARLADDLNEKIAQRPGPMELVEKNILPVESSLKEAIIVGQVNYPKVAD-----------SSSFDEDSS--------------DALSPEQPASHES-QGSVPSPLEARVSEPLLSATSASPTQVVSQLPMGRDSREMLFLAEQPPLPPPPLLPPSLTNGTTIPTAKSTPTLIKQSQPKSAS--------------------------------------------------EKSQRSKKAKELKPKVKKLKYHQYIPPDQKQDRG---APPMDSSYAKILQQQQLFLQLQILNQQQQQ----HHNYQAILPAPP-------------KSAGEALGSSGTPPVRSLSTTNSSSSSG------------APGPCGLARQNSTSLTGKP---------------------------------GALPAN------------------LDDMKVAELKQELKLRSLPVSGTKTELIERLRAYQDQISPVPGAPKAPAATS-------------------------------------------------------------------------------------------------ILHKAGEVVVAFPAARLSTGPALVAAGLAPAEVVVATVASSG--------------------VVKFGSTGSTPPVSPTPSERSLLSTG-DENSTPGDTFGEMVTSPLTQLTLQASPLQILVKEEGPRAGSCCLSPGGRAELEGRDKDQMLQEKDKQIEALTRMLRQKQQLVERLKLQLEQEKRAQQPAPAPAPLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNH---IDPCAVAPGPPSVVVKQEALQPEPEPVPAPQLLLGPQGP-------SLIKGVAPPTLITDSTGTHLVLTVTNKNADSPG--------LSSGSPQQPSSQPGSPAPAPSAQMDLEHPLQP-------------------------------LFGTPTSLLKKEPPGYEEAMSQQPKQQENGS--SSQQMDDLFDILIQSGEISADFKEPPS-----------LPGKEKPSP-KTVCGSPLAAQPSPS---------------------------------------------------------------AELPQAAPPPPGSPSLPGR------------------------LEDFLESSTGLPLLTSGHDGPEPLSLIDDLHSQMLSSTAILDHPPSP----------------------------------------------MDTSELHFVPEPSSTMGLDLADGHLDSMDWLEL---SSGGPVLSLAPLSTTAP------------------SLFSTDFLDGHDLQLHWDSCL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQH5-1", "uniprot_id": "A0A8M3AQH5_DANRE", "id": "A0A8M3AQH5-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEAMEEESKPIVPTPAVSTASASSPQSEAVTNELQDLSLQPAPNLP------------------------------------------------PIYERKNVLQLKLQQRRTREELVDQGIMPPLKSSASFHEQRRSLERARTEDYLKRKIRSRPERSELVRMHILEET--SAEPSLQAKQLLLKRARLADDLNDKISQRPGPMELVHKNILPVHSSIKQAIIE--TEFPKVEAE----------NSSFDEESS--------------DAFSPEQTAIQDSPLGHTHLPTSAELPANEATPKQVPPPP--------------------PPALPSPTPQQKLLNG---TTGQKQAPALQKSGKVSSE--------------------------------------------------RPAQRSKKVRDNKPKVKKLKYHQYVPPDQKAEREP--PPLLDSSYAKLLYQQQLFLQLQIINQQQQN-----YNYHTILPAPP-------------KPPADQQPALANGQSQSKNDTPPQSTST------------NLTS---QNQQSTINVGRVNI-------------------------------SPLPPN------------------LEELKVAELKQELKLRGLTVSGTKNDLIERLRNFQEQNGGTS--PPTPKTNT-------------------------------------------------------------------------------------------------PSALGGGASSTHQSTDRNLMVASFQFG-ATAEGGGTLTTAPM--------------------MMQFGSTSSSPPVSPAHSERSSTGMSPDEASCHADAFGEMVSSPLTQLSLQPSPPLPTTVCIKEEPCSQTYQSSSCMLSRSADKDQMLLEKDRRIQELTNMLLQKQQLVESLRLQLEG-KRVQEPNPVKEALPAAVIEALRVTVKEEVMEVVEDSEMVTEPQVELEQQQ---RIVMRQNQRNLLQQTHQRKRKTQKQQRQFPQALTNQQSSPVSSVPVSPVNPNSTPTIVTDGNGNQFLLTLSNQHTEAPARGRRPQGKATNQSRLQRLQSTSTTLPNQSEAELLNNNNQPEPIQTVILKQPIKKALKPDLNVATNYKASSSSFVSTSFFSSVDSMNDGDVVPSSPNNNNNIENVSQQHVDDLFDILIQRGEISENFKASPDP----------VLERLRPNTPLTLSFSPLNLSPASENTIKT-------------------------------------------------------LIAEPRPPSIKVPTSCATGAGR------------------------LEDFLESTTGKPLLGVEPGG--PTTLIVDLHNQMLSTPSILDHPRCP----------------------------------------------MDTYDISFSSHSAS----DLVDSAPDSMDWMELGVGASAGEVPGLVHINGHNPS-----------------SLFSADFLDTSDLN--WSSL----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z043-1", "uniprot_id": "B7Z043_DROME", "id": "B7Z043-1", "name": "", "aln": "MPVIADAASDEPPAKCCKHCEESTQSVDGGPASWRLTLDQDLIDTLKGNFPSWFQGSAGGGGGAGGAASKQNPQQHNHQLAQQKHHQLVATSVIPITIDTKLAASNTNTLQQHQQQTAILGHSSSSASPASSVSSNSSKKSISSSLSSCSSSSSNSSSCGSNHCNSKSVSSGAKGAGSATASRFLNKSTSTSPTKSLSRTLKATQKPNGNHKVGQLVKSASLHSLSSGSSGSSSGNSASGSSSLLATISTSPLTTVELISSAACSGLLATRLSGKDLEHSFQDIILLHEAYDDMSEGEQRLHATFLGSSDDGNNSDCYDARQSPPKAIVDSSPLQPAMDKNKESLKVKLMVRRPHSQLVEQGIIPSLKTSPAIHEQCKQLERAKTSDLLKAKIQQRPNREDLERLHILEEDECHIDPSLAEKQRMLKKARLADQLNSQIQHRPGPLELIKKNILHTEKPIEKIVKEGLVSFKATSEGLLTRPQHPHSYVTFDDDSLSSESDTRQTPPRLDEAMVATSSSPTDVLQAAAASAGIVTMALTMPTAGQLVVTSPQILPQQQQPKAIVVPAPVPPPPPPPPPLPMASIIKVKQETANLYEELCQSVTGTTASPVNHLYSPCSLASSTSTLSPLSSIASPPPPPMTTTRLHLAPVSVKSDAPGKDKNRKKSKSKPVSKARTIKFHEYKGPPSAAGQKQDQTQPEETSYQLMLEQQNCLLKFLENLNKNQSIIPAPSAPGVMLPAAPGATNNSITVTTKTVPALASQSAPAPAPISLPNTISITSSSGGAPLNFGDATMLTPTPAATPTPPTLSLIAAPQQQLQLHQQHQQLHQPTPVQHPPPLPSPALSVSSSIPPSPATSYAESTTSSITDLARLEKMKVSDLKQHLKRRNLPVSGPKPHLIERLKPYLPLEPLDSNVTPAPTSNNSNTTPEVITISDAMDTSNCGLLEQPPPVTMLVSDASMEHEQMDVVQQQMDNTHPMTLQTILPPQPQTATIILTNEELLREQQRKIDELQRQLQRSQQELQKIRQRQQQQQHQQQQTVTAQVVNALPSQQITLITTTSNGPQQTLTVMPQQVEKNFPAKVTVKATGGNSNHKVNGLQQQGSAAKKPASSNSNSNSNISSSNPPPINQKMVVKQQLEAKIQKQKAAAAAAAQQQQQQQQQQQQQQQQQALQQQQQQQQQQQQVRLLTQKTQTVFIPFNNNNHINNASAKTTTKKSNVPANNTNTTTATMMQAAKPAAVAAAAASPGNQHHNNLGLLWNEGNQTILLLGLNDQHMTAHTLGNISLTATTTTTAAPPAATPVAASTIAPPKKILNGHQRTNSLPSIVFPIETKSIITQQQLQQLQQQQQQQQQFQPVQQPKQQQLNQVDIKPAPAPPPQYEEATKQLAASKAAALNG-----LLPLVKIKEEPVQSPAPSAAPLPQTAPLCKRKTASIKSEQVSDVLDILIKQGELPESAALEPITPLTPLPELSMFNGATPTTAAGGASIVPLVPKLETPVTPVQNLDVAMDTNVQHVGFASNQAPNHVFIESIDMASPLQTDSSAIDAESVAKTLDIFLEQHHATPPPSTPPKSCHSGSEKPNSPDAKLNHFDEYELLELMSQQLEMDMGDDSSGYCHASAAKSSNNNGNLRRDLNPSLQPSINELLDASSPDNVLLNNNTGADVDFDADSFVAQLSQHVTGNGNSPGVNCNGSIESSSSAVNSHFGSHSTPMDCDDFESTLNSFMQAVTQPQAGQHVEYATSTSMANGTGGGMGVDNGTGGAVDAFNASGDIFDLFNMDDYKMNWAAGDFTV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.**:..::*** :.****:*.* ** **:.**:* :* *:***** :*** ** **:*****:**.:* :****:**:.**** ....::: : ..: . :**::* :*: . ..: : . . . . :. . . . ::. . :*.*. . .*.:.:*:*:* * . : . ::** :* **: :*:: :::*. .:***.* .. : . . .:* . : . ..:*.. *:.:**::***.** *.*.***.* .*****: : . . :* :.. . * . . .. : .:: :: . .*. *. .: * .. * . :.. ..*:.* : . . : . . :::* ::::: : . : * .: : : :: :: ::. . * : : : :: : . . . . :.*. : :. *. : . . * . * :: * . . . . * :.: ..:::.*::****: **:. . * . . . ** . . * . * .. : . : *: :.::* . .* **: .: .: * .. .* .: : * ...:. *: . *: : .. . : * *::: * : * : ", "identical_positions": 137, "similar_positions": 266, "identity": "7.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121205-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9Q7T7-1", "uniprot_id": "CHADL_MOUSE", "id": "E9Q7T7-1", "name": "Chondroadherin-like protein", "aln": "MERPQS-SIWV-FMLLLFMVLLQSPAWHVAAQRCPQTCVCDNSRRHVTCRHQNLTEVPNTIPELTQRLDLQGNILKVLPAAAFQDLPHLTHLDLRNCQVEMVAEGAFRGLGRLLLLNLASNRLSTLPQEALDGLGSLRRLELEGNMLEELRPGTFGALGSLTTLNLAHNALVYLPAMAFQGLLRTRWLQLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGAALSQARSLARLELGHNPLTYTGEEDGLALPGLRELALDHGSLQALGPRAFAHCPRLHTLDLRGNQLTTLPPLQVPGQLRRLRLQGNPLWCACHARPLLEWLVRARVRSDGACRGPRRLRGEALDTLRPSDLRC-PGDAAAGDGDGDEDEDRPAGPRAPPLRSPHG--EAAWATPCPPACACVAETRHSTCDGRGLQAVPRGFPNDTQLLDLRRNHFPSVPRAAFPGLRHLVSLHLQHCGVAELEPGALAGLDRLLYLYLSHNQLSGLSAAALEGAPNLGYLYLEHNRFLRIPG-TALRALPTLVSLHLQDNAVDRLAP-GDLAGARALRCLYLSGNHITQVSPGALGPARELEKLHLDRNRLREVPTGALEGLPALKELQLSGNPLRALPDGAFQPVGRSLQQLFLNSSDLEQISPRAFSGLGKGLRSLYLHKNQLQSLPAPLGLSGLELVDLSGNPFHCDCQLLPLHRWLTGLNLRVGATCATPPSVRGQKVKVAAPVFEACPGWTAR---------------------------------KAKRTPTSRGSARRTPSLSRH---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NUI6-1", "uniprot_id": "CHADL_HUMAN", "id": "Q6NUI6-1", "name": "Chondroadherin-like protein", "aln": "MEGPRS-STHVPLVLPLLVLLLLAPARQAAAQRCPQACICDNSRRHVACRYQNLTEVPDAIPELTQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPPLQGPGQLRRLRLQGNPLWCGCQARPLLEWLARARVRSDGACQGPRRLRGEALDALRPWDLRC-PGDAAQEEEE--LEERAVAGPRAPPRGPPRGPGEERAVAPCPRACVCVPESRHSSCEGCGLQAVPRGFPSDTQLLDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNRFLQVPG-AALRALPSLFSLHLQDNAVDRLAP-GDLGRTRALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALPALPSLSQLELIDLSSNPFHCDCQLLPLHRWLTGLNLRVGATCATPPNARGQRVKAAAAVFEDCPGWAAR---------------------------------KAKRTPASRPSARRTPIKGRQCGADKVGKEKGRL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXH9-1", "uniprot_id": "E7EXH9_DANRE", "id": "E7EXH9-1", "name": "Chondroadherin-like protein", "aln": "-MRPTVG--------CLLLSLMMSVG---QTLKCPRVCVCDNTKLTVKCIGNNLTHIPPTIDEIIVKLDLKKNNFGELPKNAFKHTPYLTQLSLQGCSVQAVREGAFRGLSRLLQLDLTNNNIDILYQESFDGLSSLKQLYLDRNRIEEIHPGAFAALNSLNLLSLTYNQLVYLPNMAFQGMMNIQMLHLSHNSLNNLATEAFAGLLALTHLNLDHNELQYFPTKTMTRLIEVTHLDMSYNPMTYLVEES-VVMPKLTHLSLKHNALQDLSESTISLSPVISHLDLSFNQLSYIQALAASTHLTSLNLTGNPIRCTCLLRDLKLWALKSGIRLFGVCAWPPHLSDEPLENVQEQDLRCRPQDEWTSDVIEEGTKEEEEGVQEKTVSTAKS----KKTRKCPKDCLCEYAAQHATCENRGHTKVPSGFPRKTLLLDMRGNHFHYLPSKSFPGIPEVVSLHLDSCKIHEIEGGAFQGMKNLIYLYLSDNQLSSLDAKVFEGAHEIMYLHLEDNKLTHFPSSATLTHIPKLLELHLERNLIAKLEPSGLLSPVLQLTGLYLNNNSIATIVPKALDPAPKLDVLHLEDNVLTDVPSDALDHAPLLTELHLSGNLIRWIGPRAFRVVAESLKNLLIDRMGLQKMSVRSLAGFGPRLLSLSLEDNLLEELPDLSPLAGLQNLSLNKNPLMCDCKLLPFYRWLEKMSLRVEAVCFYPSELRGQSVMESA-IYKNCSIENAHSFNETSIPTKAHEPNIPNPTQPTEPSYAKLKLAKTKIAATPKKTKSKEFKPERALKMTRPNKKKRRRPKMKLPMI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:: *: : . : :**:.*:***:: * * :***.:* :* *: :***: * : :* **: *:**:*.*: *.*: * *******.*** *:*:.*.: * **::***.**::* *: * :**::**:*.**.:* *.*::* ***** *****::. : *:****:*. **.**:*** ** :*.*.***** :* .::: :::*::.:**:** **. :.:* * .* *. .:** *. ::: .* : *** *** : .* . :* *.* ***: * * * * * :: :* *.* * :* .*.*: :: **** * * : : * : . ..:. . ** * * ::*::*:. * ** *** .* ***:* *** :* :***: .:*****: * : *:* **: *: .*:*****.***:.*.* .:*** .: **:** *:: :.*. ::* :*.*..***: * : :* * * *. . * :**..* *: : **.** :*: ***: * * :**:.**: * * **:**** :* : **: *..**::*::: .*:::. :::*:* * ** *..* *. ** *: *: :.*. **: ***:***::*** :.*** *.* *.. *** * :* ::: *. *: *:* :.:.: : : * ", "identical_positions": 288, "similar_positions": 223, "identity": "35.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121205-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9Q7T7-1", "uniprot_id": "CHADL_MOUSE", "id": "E9Q7T7-1", "name": "Chondroadherin-like protein", "aln": "MERPQSSIWV-FMLLLFMVLLQSPAWHVAAQRCPQTCVCDNSRRHVTCRHQNLTEVPNTIPELTQRLDLQGNILKVLPAAAFQDLPHLTHLDLRNCQVEMVAEGAFRGLGRLLLLNLASNRLSTLPQEALDGLGSLRRLELEGNMLEELRPGTFGALGSLTTLNLAHNALVYLPAMAFQGLLRTRWLQLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGAALSQARSLARLELGHNPLTYTGEEDGLALPGLRELALDHGSLQALGPRAFAHCPRLHTLDLRGNQLTTLPPLQ-VPGQLRRLRLQGNPLWCACHARPLLEWLVRARVRSDGACRGPRRLRGEALDTLRPSDLRCPGDAAAGDGDGDEDEDRPAGPRAPPLRSPHG--EAAWATPCPPACACVAETRHSTCDGRGLQAVPRGFPNDTQLLDLRRNHFPSVPRAAFPGLRHLVSLHLQHCGVAELEPGALAGLDRLLYLYLSHNQLSGLSAAALEGAPNLGYLYLEHNRFLRIPGTALRALPTLVSLHLQDNAVDRLAPGDLAGARALRCLYLSGNHITQVSPGALGPARELEKLHLDRNRLREVPTGALEGLPALKELQLSGNPLRALPDGAFQPVGRSLQQLFLNSSDLEQISPRAFSGLGKGLRSLYLHKNQLQSLPAPLGLSGLELVDLSGNPFHCDCQLLPLHRWLTGLNLRVGATCATPPSVRGQKVKVAAPVFEACPGWTARKAKRTPTSRG----SARRTP------------SLSRH------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NUI6-1", "uniprot_id": "CHADL_HUMAN", "id": "Q6NUI6-1", "name": "Chondroadherin-like protein", "aln": "MEGPRSSTHVPLVLPLLVLLLLAPARQAAAQRCPQACICDNSRRHVACRYQNLTEVPDAIPELTQRLDLQGNLLKVIPAAAFQGVPHLTHLDLRHCEVELVAEGAFRGLGRLLLLNLASNHLRELPQEALDGLGSLRRLELEGNALEELRPGTFGALGALATLNLAHNALVYLPAMAFQGLLRVRWLRLSHNALSVLAPEALAGLPALRRLSLHHNELQALPGPVLSQARGLARLELGHNPLTYAGEEDGLALPGLRELLLDGGALQALGPRAFAHCPRLHTLDLRGNQLDTLPPLQ-GPGQLRRLRLQGNPLWCGCQARPLLEWLARARVRSDGACQGPRRLRGEALDALRPWDLRCPGDAAQEEEE--LEERAVAGPRAPPRGPPRGPGEERAVAPCPRACVCVPESRHSSCEGCGLQAVPRGFPSDTQLLDLRRNHFPSVPRAAFPGLGHLVSLHLQHCGIAELEAGALAGLGRLIYLYLSDNQLAGLSAAALEGAPRLGYLYLERNRFLQVPGAALRALPSLFSLHLQDNAVDRLAPGDLGRTRALRWVYLSGNRITEVSLGALGPARELEKLHLDRNQLREVPTGALEGLPALLELQLSGNPLRALRDGAFQPVGRSLQHLFLNSSGLEQICPGAFSGLGPGLQSLHLQKNQLRALPALPSLSQLELIDLSSNPFHCDCQLLPLHRWLTGLNLRVGATCATPPNARGQRVKAAAAVFEDCPGWAARKAKRTPASRP----SARRTP------------IKGRQCGADKVGKEKGRL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q881-1", "uniprot_id": "F1Q881_DANRE", "id": "F1Q881-1", "name": "Chondroadherin-like protein", "aln": "----MGSIPTWPVIILFALKIHT----ALSAKCPKVCVCDSIQLTIACVNKNLTEVPPTIDEITVKLDLRGNDLQELPTGAFAHTPYLTHLSLQNSNIRRVREGAFRKLGRLVLLNLANNKIEILYQESFDGLSSLKQLIIDRNRVEEIQPGAFSQLGFLNLLSLTHNQLVYIPNMAFQGLQNIKWLRLSHNFINYLATEAFAGLFTLTRLSLDNNELQFFPTETMTRLSEVTRLELSFNPMTYLGEES-VSMLKLTHLLLDHNSLQDFSNAAILLSPRLTHLDLSHNQLRILQPMAPGSPKLTRLNLAGNPIYCSCYLRPLREWATRERVRLGGTCGGPAHLSGENLEVVQPVNLRCLSQEAMLKAEL-EEQVLPALPTTPS--PKKG--------KCPANCACETENRHSSCENKGHTKIPRGFSPDTRLLDLRGNHFHYIPANSFPGTAEVVSLHLQRCKIHDIEDGAFSGMKSLVYLYLSENDLTSLTPEAFKGLPHLTYLHLEKNRFTQFPKGAFKLLPGLLALHMENNAIAKLETGLLTSAEKLRGLYLTSNAITAAAPQAFNPAPDLETLHLGSNKLQEVPTEAFSKARSLAELKLSHNPIRWIGAGAFQPVGTTLRHLYLDHMGLEKVSTDFLAGLGSGLRSLLLEGNQLEELPDLSPLTGLEVINLAENPLLCDCPLLPLRKWIEQVNLKVRATCGHPPELRGQRVKDVH-VFKSCPGGKSPSAQHPKPTRAPKPESARVSPPKIIKRVDRKATGKSRKGAKPHTVQKTAMKKRKSA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* . :: *: : : : . : :**:.*:**. : ::* :****** :* *:* :***:** *: :*:.** *:****.*::.::. * ***** ****:*****.*:: * **::***.**::* :: * :**::**:*. ** * *.*:** ***:* ****** . :**:**** :. **.**:*** :* ****.:**** :* .::: ::****..**:** ***. ::: * .* ** .:** :. *: .*** *** *** * *: . :* **.* ***::*.* *** ** .* *** .*:* ** :* ** *:.::* :*** .: * . : :: * * :*. . :* ** *.* .*.***:*:. * :****. **:***** *** :* :*** .:******:* : ::* **::*: *:*****.*:*:.*:. *::* *.* **:**:*** :.* *:: ** *.:**:::**: :* .* * :. ** :**:.* ** .: *:.** :**.***. *:*:**** *:. :* **:** **:* : ******* :*::*:*: .**::.. ::*** **:** *. ***. ** *: **:::*: **: *** ****::*: :**:* ***. **. ***:** . **: *** : .*::. .:* *** :* .*: ", "identical_positions": 332, "similar_positions": 216, "identity": "42.24%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121207-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P17858-1", "uniprot_id": "PFKAL_HUMAN", "id": "P17858-1", "name": "ATP-dependent 6-phosphofructokinase, liver type", "aln": "MAAVDLEKLRASGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKQANWLSVSNIIQLGGTIIGSARCKAFTTREGRRAAAYNLVQHGITNLCVIGGDGSLTGANIFRSEWGSLLEELVAEGKISETTARTYSHLNIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVTLSGNQSVRLPLMECVQMTKEVQKAMDDKRFDEATQLRGGSFENNWNIYKLLAHQKPPKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISHGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKVNVEHMTEKMKTDIQRGLVLRNEKCHDYYTTEFLYNLYSSEGKGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWLSEKLREVYRKGRVFANAPDSACVIGLKKKAVAFSPVTELKKDTDFEHRMPREQWWLSLRLMLKMLAQYRISMAAYVSGELEHVTRRTLSMDKGF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12382-1", "uniprot_id": "PFKAL_MOUSE", "id": "P12382-1", "name": "ATP-dependent 6-phosphofructokinase, liver type", "aln": "MATVDLEKLRMSGAGKAIGVLTSGGDAQGMNAAVRAVTRMGIYVGAKVFLIYEGYEGLVEGGENIKPANWLSVSNIIQLGGTIIGSARCKAFTTREGRLAAAYNLLQHGITNLCVIGGDGSLTGANIFRNEWGSLLEELVKEGKISESTAQNYAHLTIAGLVGSIDNDFCGTDMTIGTDSALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWENFMCERLGETRSRGSRLNIIIIAEGAIDRHGKPISSSYVKDLVVQRLGFDTRVTVLGHVQRGGTPSAFDRILSSKMGMEAVMALLEATPDTPACVVSLSGNQSVRLPLMECVQVTKDVQKAMDEERFDEAIQLRGRSFENNWKIYKLLAHQKVSKEKSNFSLAILNVGAPAAGMNAAVRSAVRTGISEGHTVYIVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKPHLEAIVENLRTYNIHALLVIGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDFSLGSDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFNIHDLKANVEHMTEKMKTDIQRGLVLRNEKCHEHYTTEFLYNLYSSEGRGVFDCRTNVLGHLQQGGAPTPFDRNYGTKLGVKAMLWVSEKLRDVYRKGRVFANAPDSACVIGLRKKVVAFSPVTELKKETDFEHRMPREQWWLNLRLMLKMLAHYRISMADYVSGELEHVTRRTLSIDKGF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B5P7-1", "uniprot_id": "A0ACD6B5P7_DANRE", "id": "A0ACD6B5P7-1", "name": "ATP-dependent 6-phosphofructokinase", "aln": "MSSAGLEKLRMTGAGRAIAALTSGGDAQGMNAAIRAVTRMGIYVGAKVYLVYEGYQGLVDGGDNIKLANWQSVTNIIQLGGTVIGSARCKAFTTREGRLAAAFNLVKRGISNLCVCGGDGSLTGANIFRAEWSGLLEELVQKGRITAETAQKHGHLNIVGLVGSIDNDFCGTDMTIGADSALNRITEIIDAITTTATSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWEELMCARLEESRSKGCRLNIIIIAEGAISRSGEAITSNYIKDLVVSRLGYDTRVTVLGHVQRGGTPSAFDRVLSSKLGVEAVVALLEATPDTPACVIGLSGNQAVRLPLVEAVEMTKEVQRAMNEKRFEEAIQLRGRSFENNWSIYKLLAYQKPAAVQSEHSIAILNVGAPAAGMNAAVRSAVRVALASGHRVYIVNDGFEGLAKGAVNEVSWNQVAGWTGLGGSLLGTKRTLPSTCMDKLVENLNKFSIHSLLVIGGFEAYEGVLELVEARGRYDELCIPMCIIPATISNNVPGTEFSLGSDTAVNAAMSSCDKIKQSASGTKRRVFVVETMGGYCGYLATTTSIAVGADAAYIFEDPFNIHDLTTNVVHLTEKMKKDIQRGLVLRNEKCHEHYTTDFIHKLYSAEGKGVFDCRVNILGHLQQGGVPTPFDRNYGTKLGVRAVQWLTEKMNDSFRQGRVFANTPDTACVVGLYKKAMTFSPVTELKEQTDFEHRMPKTQWWLNLRLMLKMLAKYQTSFNEYVTGEIEHVTRRSLSIDTGF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::..***** :***:**..*************:**************:*:****:***:**:*** *** **:********:*************** ***:**:::**:**** ************* **..****** :*:*: **:.:.**.*.******************:****:** *:******** *******************************************::** ** *:**:*.************.* *:.*:*.*:*****.***:*********************:****:*:***:*************: *****:*****:*.*::**:**:**:::**:** **** ******.******:** . :*:.*:*********************..:: ** **:*:********* *:**.*::**** * ***:********. :: :***:. :.**:***:**********:********:**** **:************:*************.***:*************:*************.*.*********:**********..** *:*****.**************::***:*:::***:**:******.*:********.**************:*: *::**:.: :*:******:**:***:** **.::********::********: ****.*********:*: *: **:**:******:**:*.**", "identical_positions": 598, "similar_positions": 144, "identity": "76.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121210-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99LY2-1", "uniprot_id": "GDPD3_MOUSE", "id": "Q99LY2-1", "name": "Lysophospholipase D GDPD3", "aln": "-MIPLLYFVLPTLGS---YVMLSIFFLRRPHLLHTPRAPVFPIRLAAHRGGSGERLENTMEAVENSMAQRADLLEFDCQLTRDGVVVVSHDKNLSRQSGLNKDVNTLDFEELPLYKEELEIYFSPGHFAHGSDRHMISLEDVFQKFPRTPMCLEVKERNEELIHKVANLTRRFDRNEITIWAAEKSSVMKRCRAANPEMPMAFTIWRSFWILLLYYLGLLPFVSIPEKF-FFCFLPTIINRTYFPFRCGWMNQLSATITKWIIMRKSLIRHLQ-DRGVQVLFWCLNEESDFEVAFSLGANGVMTDYPTALRHYLDKQEEETQPPQPEALSCLSLKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A1N8-1", "uniprot_id": "D4A1N8_RAT", "id": "D4A1N8-1", "name": "Lysophospholipase D GDPD3", "aln": "-MIPLVYFVLPTLGS---YVILSIFFLRRPHLLHTPWAPGFSIRLAAHRGGSGERLENTMEAIENSMAQRADLLEFDCQLTRDGVVVVSHDKNLSRQSGLNKDINTLDFAQLPLYKEELEIYFSPGHFAHGSDRHMISLEDVFQKFPRTPMCLEIKEKNEELIHKVANMARRFNRNEITIWTSEKNSIMKRCKAANPEMPTAFTIWRSFWILLLYYLGLLPFVSIPEKF-FFCFLPTIINRTYFPFSCGWMNKLSATVTKWAIMRKSLIQYLQ-DRGVQVLFWCLNEESDFEVAFSLGANGVMTDYPTALRHYLDKQE------QRDSASSV----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7L5L3-2", "uniprot_id": "GDPD3_HUMAN", "id": "Q7L5L3-2", "name": "Lysophospholipase D GDPD3", "aln": "-MSLLLYYALPALGS---YAMLSIFFLRRPHLLHTPRAPTFRIRLGAHRGGSGELLENTMEAMENSMAQRSDLLELDCQLTRDRVVVVSHDENLCRQSGLNRDVGSLDFEDLPLYKEKLEVYFSPGHFAHGSDRRMVRLEDLFQRFPRTPMSVEIKGKNEELIREIAGLVRRYDRNEITIWASEKSSVMKKCKAANPEMPLSFTISRGFWVLLSYYLGLLPFIPIPEKF-FFCFLPNIINRTYFPFSCSCLNQLLAVVSKWLIMRKSLIRHLE-ERGVQVVFWCLNEESDFEAAFSVGATGVITDYPTALRHYLDNHG-------PAARTS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z9C9-1", "uniprot_id": "A0A8M6Z9C9_DANRE", "id": "A0A8M6Z9C9-1", "name": "", "aln": "-MDTVSWVLLLCLAVL-FYVVCSLFLLRYPLILHKRKRLEFYCRHISHRGGSGERIENTMEAFTHAVSAGTDMLEMDCHLTLDGYVVVSHDNNLLRQTGDDKTVSSLKFQDLPLYEEKLEVTFYVGHYSTGKDRRFVLLENVLKNFPNMPMTLEIKENNDLLIKKVSNLVHKYGREHITVWASEEHEVMAKCLKQNPSMPYMFTMRRVIMLLLLFYTGLLPFVPLGESV-LMFYLPRIINRTYIPEEAYMKNRFVVYLLQKLITWKSLFEHLI-KRGLQVQLFVCNEETDMAAAFAMGATGVMTDYPTVLSDYIRKHP-------PPPAVY-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08959-1", "uniprot_id": "PGC1_YEAST", "id": "Q08959-1", "name": "Phosphatidylglycerol phospholipase C", "aln": "MVEIVGHRAFKARYPENTLLAFEKAYAAGADVIETDLQMTSDGMVVVNHDSDTGRMWDKNLVIGESTWEEVKRLRCKEDGSLAMMTLKEILTWAVCHPGAKLMLDIKFTNEKIIMIKTFVIMLEVKNDLKFWQERITWGLWLLDWYDFGIETGVLKDFKVIVISLSLDIASQFVKRSLTLNDP-HYKLFGISVHFVSSWTSQFRLRLLPVLMKNDIKVYLWTVNKPIDFKYLCELPIHGAITDDPIKARKLCDGHTVAKKPTAEKKFVAPSLASVDGLRFHAFIKVYNILCTLLYSKWVHIKLCGWSIAYVIFLFLRT----------IHFL----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . . ::.. ::... : :. .. .: . *. . . : .: . :.* . :. : : : : : : : :.:: ::. : :* : :* .:. :: :. :*: . . .:: . .. . * : :: * : .. : ** * * . . : * : * *::. : : :: . : .:. . :: : ", "identical_positions": 14, "similar_positions": 97, "identity": "4.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121210-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PUL5-1", "uniprot_id": "PRRT2_MOUSE", "id": "E9PUL5-1", "name": "Proline-rich transmembrane protein 2", "aln": "MAASSSQVSEMKGVEDSSKTQTEGPRHSEEGLGPVQVVAEIPDQPEALQPGPGITAAPVDSGPKAELAPETTETPVETPETVQATDLSLNPEEGSKASPSPSPSEARQEPASKPDVNRETAAEEGSEPQSTAPPEPTSEPAFQINTQSDPQPTSQPPPKPPLQAEPPTQEDPTTEVLTESTGEKQENGAVVPLQAGDGEEGPAPQPHSPPSTKTPPANGAPPRVLQKLVEEDRIGRAHGGHPGSPRGSLSRHPSSQLAGPGVEGGEGTQKPRDYIILAILSCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIVALVGGVLIIIASCVINLGVYK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z6L0-1", "uniprot_id": "PRRT2_HUMAN", "id": "Q7Z6L0-1", "name": "Proline-rich transmembrane protein 2", "aln": "MAASSSEISEMKGVEESPKVPGEGPGHSEAETGPPQVLAGVPDQPEAPQPGPNTTAAPVDSGPKAGLAPETTETPAGASETAQATDLSLSPGGESKAN--CSPEDPCQETVSKPEVSKEATADQGSRLESAAPPEPAPEPAPQP----DPRPDSQPTPKPALQPELPTQEDPTPEILSESVGEKQENGAVVPLQAGDGEEGPAPEPHSPPSKKSPPANGAPPRVLQQLVEEDRMRRAHSGHPGSPRGSLSRHPSSQLAGPGVEGGEGTQKPRDYIILAILSCFCPMWPVNIVAFAYAVMSRNSLQQGDVDGAQRLGRVAKLLSIVALVGGVLIIIASCVINLGVYK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F7R0-1", "uniprot_id": "E7F7R0_DANRE", "id": "E7F7R0-1", "name": "", "aln": "-------------METEYHQASLGSLVCTQDEEP--TSCQIPG-PVTYQPGP-------------------------------------------------------------------------------------------------AASDSFPCLRPLTFPQQPKEEVRCSGEVIVMVKDKAESADKICSSSNDAFS-SKPILSSPPRRHHSLPHTHHPHVGRTRMGSRSSSIAYTAFS--PRPSISRHSSIATNPP-----LDRSKPKDYLILAVIACFCPVWPINIVGFVYSIMSRNSLEQGNVDGARRLGRVAKLLSVVSLVGGAVIIIA-CAVNLSINVKS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . : *. . * . . :*. * : **** . . * * :* .: *.:* . : . :* *.. : .:.*. . . * *** : . .: *:* : : . *: ... ** *:***.* * . .**:**:***:::****:**:***.*.*::******:**:****:**********:*:****.:**** *.:**.: ", "identical_positions": 84, "similar_positions": 68, "identity": "24.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121211-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6NCL1-1", "uniprot_id": "GEMC1_HUMAN", "id": "A6NCL1-1", "name": "Geminin coiled-coil domain-containing protein 1", "aln": "MNTILPCQDQYFVGGQSYNCPYSTTTSESSVDVSTETWVSFWAAGLLDNRELQQAPQAQESFSDSNFPLPDLCSWEEAQLSSQLYRNKQLQDTLVQKEEELARLHEENNHLRQYLNSALVKCLEEKAKKLLSSDEFSKAYGKFRKGKRKSKEQRYSPAEIPHPKNAKRNLSSEFANCEEQAG-PPVDPWVLQTLGLKDLDTIDDTSSAN---YS-ALASHPRRVASTFSQFPDDA---VDYKNIPRE----------------DMPIDYRGDRTTPLHSTATHGEDFHILSQLSNP----PVGLKTLPYYTAHVSP---------------------------NKTEMAFSTSLSPHCNVKTHSFHQGQAFVRRDEEGGWKFTWVPKQS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3URY2-1", "uniprot_id": "GEMC1_MOUSE", "id": "Q3URY2-1", "name": "Geminin coiled-coil domain-containing protein 1", "aln": "MNSILPCQDQYFVGGQSYNCPYSTTTSESGVDVSKETWVSFWAAGLLDNTELQQAPQVLESPSELSFPVLDSCSWEEAQLSSQLYRNKQLQDTLLQKEEELARLHEENNHLRQYLNSTLVKRLEEKAKKLLSSDEFSKVFGKLRKEKRKPKEHRHSPAEIPQFKTAKRNLSTEFSNCEEQPG-PHVDPWVLQTLGLKDLNTIDDTLPAN---YS-ATTSHPRAVPSISSLFVHDA---NGYANVPR-----------------DLHLDYVGQGTHGSHTTSIHQEDCHSFPRLSNP----PVRVQTLPYHTADVSP---------------------------NKTEMAFSTSLSPHCNVKTHSFHQGQAFVRRDEEGGWKFTWVPKQT-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FDS4-1", "uniprot_id": "E7FDS4_DANRE", "id": "E7FDS4-1", "name": "", "aln": "---MLSCQDLSFAGGQRYEY-CASTSADGSVDVSTTTLVSLWDAGPLDNAARQHEPPRRDSLLES--GLGHQPTWHD-QLSPQLQRNKQLQDTLMQREEELARLQEENNKLKEFLNSSYVKSLEEKSKKLLFNGKVPDVS-RHRKRMHGDFRNLSQLLHTSEGKRTCRNLSLEFCSAEELAATPPLDSWVLETLGLQDENTINPERSLNTTTFSRPLPTEDRYSVDNTTGFSPNAGTHCDYSSIVDSSSNCSLDTSSGYSTSQSLGSDYSTLDPSALYTITSTGSPVSSPPALTTAQHFTPPRAASTPYRPQDVSPYYSTPGCGSSTSPGGDKQLFSTPRMSRSKTDLAFSMSLSPQNSVKTHSFPQGQAFTRRDAQGGWNFTWVPKQCS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.*** *.*** *: ::*:::..****. * **:* ** *** *: * :* : : . :*.: ***.** *********:*:*******:****:*:::***: ** ****:**** ..:.... : ** : .: . . .. * : **** **...** .. * :*.***:****:* :**: . * :* . .:. * . : * :* .* .: .: ** . :: : . . *:.. * : ** . .*** .**::*** ****: .****** *****.*** :***:******* ", "identical_positions": 138, "similar_positions": 92, "identity": "35.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121211-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61366-1", "uniprot_id": "OSTN_HUMAN", "id": "P61366-1", "name": "Osteocrin", "aln": "MLDWRLASAHFILAVTLTLWSSGKVLSVDVTTTEAFDSGVIDVQSTP-TVREEKSATDLTAKLLLLDELVSLENDVIETKKKRSFSGFGSPLDRLSAGSVDHKG-KQRKVVDHPKRRFGIPMDRIGRNRLSNSRG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P61364-1", "uniprot_id": "OSTN_MOUSE", "id": "P61364-1", "name": "Osteocrin", "aln": "MLDWRLASTHFILAMIVMLWGSGKAFSVDLASQEF---GTASLQSPP-TAREEKSATELSAKLLRLDDLVSLENDVFETKKKRSFSGFGSPLDRLSAGSVEHRG-KQRKAVDHSKKRFGIPMDRIGRNRLSSSRG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F404-1", "uniprot_id": "E7F404_DANRE", "id": "E7F404-1", "name": "", "aln": "MLGCGCVLLSCLLTLTLFHCS-AESLHIPQGRPEYVESSVVEGRSVQRGQMEQKTSGALSAKLLLHDQLVRLENDVIETKRKRSFPGSNTPLDRLSISTMDPKSNKQRKAVELPRRRVSVPIDRIGVGRLPSSRG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. . :*:: : . .: : : * .. . :* *:*:: *:**** *:** *****:***:****.* .:****** .::: :. ****.*: .::*..:*:**** .**..***", "identical_positions": 50, "similar_positions": 43, "identity": "37.04%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121212-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96RE7-1", "uniprot_id": "NACC1_HUMAN", "id": "Q96RE7-1", "name": "Nucleus accumbens-associated protein 1", "aln": "--------------------------------MAQTLQMEIPNFGNSILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRDLFNN-SRSAVVELPAAVQPQSFQQILSFCYTGRLSMNVGDQFLLMYTAGFLQIQEIMEKGTEFFLKVSSPSCDSQGLHAEEAPSSEPQSPVAQT-----------SGWPA-CSTPLPLVSRVKTEQQ----------ESDSVQCMPVAKRLWDSGQKEAGGGG-----NGSRKMAKFSTPDLAANRPHQPPPPQQAPVVAAAQPAVAAGAGQPAGGVAAAGGVVSGPSTSERTSPGTSSAYTSDSPGSYHNEEDEEEDGGEEGMDEQYRQICNMYTMYSMMNVGQTA-EKVEALPEQVAPESRNR-IRVRQDLASLPAELINQIGNRCHPKLYDEGDPSEKLELVTGTNVYITRAQLMNCHVSAGTRHKVLLRRLLASFFDRNTLANSCGTGIRSSTNDPRRKPLDSRVLHAVKYYCQNFAPNFKESEMNAIAADMCTNARRVVRKSWMPKVKVLK-AEDDAYTTFISETGKIEPDMMGVEHGFETASHEG----EAG-PSAEALQ-------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TSZ8-1", "uniprot_id": "NACC1_MOUSE", "id": "Q7TSZ8-1", "name": "Nucleus accumbens-associated protein 1", "aln": "--------------------------------MAQTLQMEIPNFGNSILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRDLFNS-SRSAVVELPAAVQPQSFQQILTFCYTGRLSMNMGDQFLLIYTAGFLQIQEIMEKGTEFFLKVSSPSCDSQGLHPEEAPSSEPQSPVAQT-----------LGWPA-CSTPLPLVSRVKTEQ-----------ELDSVQCTPMAKRLWDSSQKEAGGSGGN---NGSRKMAKFSTPDLALNRMPQPLS------MATATAAVA---------VVAVGGCVSGPSMSERTSPGTSSAYTSDSPSSYHNEEDEEEDAGEEGTDEQYRQICNMYTMYSMLNVGQTA-EKVEALPEQVVLESRSR-IRVRQDLASLPAELINQIGNRCHPKLYDEGDPSEKLELVTGTNVYITRAQLMNCHVSAGTRHKVLLRRLLASFFDRNTLANSCGTGIRSSTNDPRRKPLDSRVLHAVKYYCQNFAPNFKESEMNAIAADMCTNARRVVRKSWLPKTKPLHLVEGDNYSSFISDTCKIEPDMMSMEHSFETASHDG----EAG-PSAEVLQ-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58GTE3-1", "uniprot_id": "A0AC58GTE3_DANRE", "id": "A0AC58GTE3-1", "name": "", "aln": "MAARREKESDSSIETLSSRLQARGLCSAGLYDMAQMLQMAIPNFGNNILECLNEQRLQGLYCDVSVVVKGHTFKAHRAVLAASSSYFRDLFNSGSKSSVVELPPAVQPQSFQQILSFCYTGRLSMNLGDQFLLMYTAGFLQIQQIMEKGTEFFLKVSSPSCDSQGLHTEDAPPSEPQSPVTQTGTGSIGMGGSTAARPASCQTPLPLVSRVKTEQLPQAPQPLQEASSYSVVCTPVAKRLWEGGNREGGGGSGGSGGGGVRKAARYSQEVVRSVGGAQPQS------IALLGGSGTTNS------NSNNNNNNNSSSTPEGTSPGTPSMYTSDSPISYHDD-DEEEEIPDETTEEQYRQICNMYTMYSMLNVGATANERVESLPDHLTVESRGRGVRVRQDLASLPTELIAQIGNRCHPKLYEEGDPAEKLELVTGTSVFISRAQLMNCHVSAGTRHKVLLRRLLAAFFDRSTLANSCGTGIRSSTNDPNRKPLDSRVLHAVKFYCQNFAPSFKESEMNAIAADMCTNARRVVRKSWIPKLKLLM-AESDAYANFLSDAAKLESDGLGVENAFETGSLEGGPASESGQSSADALHGVSGDGSSLFYGALEKLGTQCALISEPDELEWNHTGFMLICTRSFKSPIKLIVLGYGSLFL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** *** ******.************************:********************. *:*:*****.***********:**********:******:*********:***********************.*:**.*******:** . ** *.************* . ** * *:*****:..::*.**.. .* ** *::* : ** . :* : : .. ...* .* *****.* ****** ***:: ****: :* :***************:*** ** *:**:**:::. ***.* :**********:*** ***********:****:*********.*:*:************************:****.*****************.*************:*******.*************************:** * * .*.* *:.*:*:: *:*.* :.:*:.***.* :* *:* .**:.*: ", "identical_positions": 373, "similar_positions": 88, "identity": "56.86%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-100", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55083-1", "uniprot_id": "MFAP4_HUMAN", "id": "P55083-1", "name": "Microfibril-associated glycoprotein 4", "aln": "MKALLALPLLLLLS--TPPCAPQVSGIRGDALERFCLQQPLDCDDIYAQGYQSDGVYLIYPSGPSVPVPVFCDMTTEG-----GKWTVFQKRFNGSVSFFRGWNDYKLGFGRADGEYWLGLQNMHLLTLKQKYELRVDLEDFENNTAYAKYADFSISPNAVSAEEDGYTLFVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRSCHFANLNGFYLGG-SHLSYANGINWAQWKG-FYYSLKRTEMKIRRA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D1H9-1", "uniprot_id": "MFAP4_MOUSE", "id": "Q9D1H9-1", "name": "Microfibril-associated glycoprotein 4", "aln": "MKALPALPLMLMLLSMPPPCAPQASGIRGDALEKSCLQQPLDCDDIYAQGYQEDGVYLIYPYGPSVPVPVFCDMTTEG-----GKWTVFQKRFNGSVSFFRGWSDYKLGFGRADGEYWLGLQNLHLLTLKQKYELRVDLEDFENNTAYAKYIDFSISPNAISAEEDGYTLYVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRSCHFANLNGFYLGG-SHLSYANGINWAQWKG-FYYSLKRTEMKIRRA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "R4GEG2-1", "uniprot_id": "R4GEG2_DANRE", "id": "R4GEG2-1", "name": "", "aln": "MITVFVVALLSVFT---MSVVSVCDGFK-----------PFDCSEIYKSGQTGSGIYSIYPAG-NTPVWVYCQMISEGKVQDNGGWTVFQRRLDGRINFYQPWEEYKRGFGTTEGEYWLGLENLYQLTRHKNYMLRVDLEDFTGRRGFAQYSSFSVG-----SEAEGYKLQISGFTDGGAGDSMTHHNGMKFSTYDKDQDIDSRNCARLRLGAFWYRNCYYANPNGVYIGGEDSTIYAIGDVWYSWKNNANFGMKLITMKIKPVS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: .:.*: :: . .. .*:: *:**.:** .* .*:* *** * ..** *:*:* :** * *****:*::* :.*:: *.:** *** ::*******:*:: ** :::* ******** .. .:*:* .**:. :* :**.* ::** *******:::*.* ****:*:***: :*** * ****:*.*::** **.*:** . ** * * .**. :.:* ***: . ", "identical_positions": 110, "similar_positions": 77, "identity": "41.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-104", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAZ2-1", "uniprot_id": "D4AAZ2_RAT", "id": "D4AAZ2-1", "name": "Zona pellucida-like domain-containing protein 1", "aln": "MEQIWLLLLLAIRVFPGSAQFNSYNCDANLHSRFPAERDISVYCGVQAITMKINFCTVLFSGYSETDLALNGRHGDSHCRGFINNNTFPAVVIFIINLSTLEGCGNNLVVSTIPGVGASGNATSVQIGNISGYIDTPDPPTVISYLPGLLYKFSCSYPLEYLVNNTQLASSSAAISVRENNGTFVSTLNLLLYNDSTYREQLIIPSIGLPLKTKVFAAVQATNLDGRWNVLMDYCYTTPSGNPNDETRYDLFLSCDKDPQTTVIENGRSQRGRFSFEVFRFVKHKNQKMSTVFLHCLTKLCRADDCPLLMPICGNRKRRDAQSWTTWAPQSTSGNAVLSAGPIITRSDETPTNNSQLGSLSVPPFQLNAVTSSLISGMVILGVMCFSLLLCSLALLHRKGSTSLVLNGVRNPVFE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGZ8-1", "uniprot_id": "ZPLD1_MOUSE", "id": "Q8BGZ8-1", "name": "Zona pellucida-like domain-containing protein 1", "aln": "MERVWLLFLLAIRVSPGSAQFNSYNCDANLHSRFPAERDISVYCGVQAITMKINFCTVLFSGYSETDLALNGRHGDSHCRGFINNNTFPAVVIFIINLSTLEGCGNNLVVSTIPGVGASGNATTVQIGNISGYIDTPDPPAVISYLPGLLYKFSCSYPLEYLVNNTQLASSSAAISVRENNGTFVSTLNLLLYNDSTYREQLIIPSIGLPLKTKVFAAVQATNLDGRWNVLMDYCYTTPSGNPNDDTRYDLFLSCDKDPQTTVIENGRSQRGRFSFEVFRFVKHKNQKMSTVFLHCLTKLCRADDCPLLMPICGNRKRRDAQSWTTWAPQSTSGNAVLSAGPIITRSDETPTNNSQLGSLSVPPFQLNAVTSSLISGMVILGVLCFSLLLCSLALLHRKGSTSLVLNGVRNPVFE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TCW7-1", "uniprot_id": "ZPLD1_HUMAN", "id": "Q8TCW7-1", "name": "Zona pellucida-like domain-containing protein 1", "aln": "MEQIWLLLLLTIRVLPGSAQFNGYNCDANLHSRFPAERDISVYCGVQAITMKINFCTVLFSGYSETDLALNGRHGDSHCRGFINNNTFPAVVIFIINLSTLEGCGNNLVVSTIPGVSAYGNATSVQVGNISGYIDTPDPPTIISYLPGLLYKFSCSYPLEYLVNNTQLASSSAAISVRENNGTFVSTLNLLLYNDSTYNQQLIIPSIGLPLKTKVFAAVQATNLDGRWNVLMDYCYTTPSGNPNDDIRYDLFLSCDKDPQTTVIENGRSQRGRFSFEVFRFVKHKNQKMSTVFLHCVTKLCRADDCPFLMPICSHRERRDAGRRTTWSPQSSSGSAVLSAGPIITRSDETPTNNSQLGSPSMPPFQLNAITSALISGMVILGVTSFSLLLCSLALLHRKGPTSLVLNGIRNPVFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PLJ9-1", "uniprot_id": "A0A8M9PLJ9_DANRE", "id": "A0A8M9PLJ9-1", "name": "", "aln": "MEWMCVILVLFKGIHLAFSQFNGFNCDPNYHSRFPGERDISIYCGVQTITLKINLCPVLYSGYTDVDLALNSRHGEPQCRGFINNNTFPTAVLFSISLSSLEACGNTLQVSTTQGINAYGNISMVQMGNISGYIDTPDPPTVISYLPGLVYKFSCSYPLEYLLNNSQLASSSAAITVKDNNGTFLSTLSLVLYNDSTFNQLISIPVSGLSLKTRVFAAVKATNLDRRWNVLMDHCYATPSGNPKDEIRYDLFFGCYKDPQTTVFENGKSQMGRFAFEVFRFVKHKNQKMSTVFLHCITKLCRADDCAILMPICGKRRRRDSEAEHTVS-GSSSGDAVITAGPIITRSDESPTNNSQLVSSSSQP--LNAVTSALISGVVVLGVMSLGLFILSLRLLRKPSPS--NLTGLWNPSSR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : ::::* : . :***.:***.* *****.*****:*****:**:***:*.**:***::.*****.***:.:***********:.*:* *.**:**.***.* *** *:.* ** : **:*************::*******:************:**:*********:*::*****:***.*:******:.: : ** **.***:*****:***** *******:**:******:*: *****:.* *******:***:** ***:*********************:*********.:*****.:*.***: * : *:**.**::**********:******* * * * ***:**:****:*:*** .:.*:: ** **:: ..: *.*: ** ", "identical_positions": 275, "similar_positions": 92, "identity": "66.27%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-108", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60347-1", "uniprot_id": "TBC12_HUMAN", "id": "O60347-1", "name": "TBC1 domain family member 12", "aln": "MVGPEDAGACSGRNPKLLPVPAPDPVGQDRKVIRATGGFGGGVGAVEPPEEADEEEEADEEEETPPRQLLQRYLAAAGEQLEPGLCYCPLPAGQAGAPPPSAAPRSDACLLGSGSKHRGAEVADGRAPRHEGMTNGDSG-FLPGRDCRDLEEARGLARAGGRESRRRRPYGR-LRLEGPGDEDADGAGSPSDWASPLEDPLRSCCLVAADAQEPEG----AGSDSGDSPASSCSSSEDSEQRGVGAGGPEEGAPPATSAERTNGGAEPRLGFSDIHFNSRNTFQVSRGQSARDHLPPAGPPVPLPAAEQGPAGASARARRSGGFADFFTRNLFPKRTKELKSVVHSAPGWKLFGKVPPRENLQKTSKIIQQ-------------------EYEARTGRTCKPP--PQSSRRKNFEFEPLSTTALILEDRPSNLPAKSVEEALRHRQEYDEMVAEAKKREIKEAHKRKRIMKERFKQEENIASAMVIWINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRAKERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIFQKGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILLQMDFIHIAQFLTKLPEDITSEKLFSCIAAIQMQNSTKKWTQVFASVMKDIKEGDKNSSPALKS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FDW4-1", "uniprot_id": "E7FDW4_DANRE", "id": "E7FDW4-1", "name": "", "aln": "-MGYSPSGVQ---KSSVISEHCGYFVDSPVKLMVESSSSGG-RGAEEGRPPPRIADVTDRQE-----NIMQGMFSNSGASQRE---KGQLQSSQE----HEATESCDEVNLPCGAKLPNGHASHNAPERVACKSSSPAGSCVSSEDDHGIANGELLVDSGSAGDAVSSAFCSGETPDEAGESLETQAGETLEALDQAERSSTDHCLGLQSSECNEGKLHRRSSTSPSPLKHSLRTFSSSTFLNTDSASLSPNDDDDEDETFSTSDRPDDLRFMDVSLKSRNTYEISRRQSAPDNIP----GVLSVAAVDLTLGQ-----RKQGISDIFSRSLFTRKQRE----AQSAPGWKLFGKVPLRESPPKDSKTIQQESNPGNLTSVSTPNLLSSGEYEAKVCKSGQSPSLPAQSRRKNLEFEPLSTTALILEDRPANLPAKSEEEAQRHRQEYDEMVAEAKKRELKEAQKKKKQMKERFKQEESIANAMVVWNTEILPNWESMRGTRRVRDLWWQGLPPNVRGKVWSLAVGNELNITSDLYEIFLSRAKERWKSFRETGSEIESD-VDSADRESSLDLIKLDISRTFPSLFIFQKGGPYHDLLHSVLGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQMAFFRVDHELMLKYFAAFEVFFEENLPRLFNHFKSYNLTPDLYLIDWIFTLYAKSLPLDVACRVWDVFCRDGEEFLFRTGLGILRLYEELLLQMDFIHSAQFLTRLPDDTPPERLFSCIASTQMISSNRKWTQVFNALIKD-KEMEKSSVPSVKNS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . :*. :..::. . *.. *:: :.. ** ** * . : :*.:* :::* :: :* . . * :.* .*: .* * .*:* ....:.. . * :.. :* :...* :.: :.. *. :*. . .: : .*:. **.. : . * . . ** .:: ** .* * .. * : ..* ...:.. . . . :... * * *: ::****:::** *** *::* * ** : . * *. *::*:*:*.**.:: :* .:************ **. * ** *** ****:. :: :.* * .*****:****************:****** *** *****************:***:*:*: *********.**.***:* .******* **.*****:********.*****************.:**************** **.** ::: *. ****:**:*************:**********:***:**********************************************:*******.:******:*********.:** *****.****:**********:******:****************************::******** *****:**:* ..*:******: ** .*.:****** :::** ** :*.* *::*. ", "identical_positions": 411, "similar_positions": 182, "identity": "51.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-111", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q460M5-1", "uniprot_id": "LRFN2_RAT", "id": "Q460M5-1", "name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "aln": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADDAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASLLTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLKTCGSPGGLKGRYFWHIREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGPFTCIAANAAGEATATVEVSIVQLPHLSNSTSRMAPPKSRLSDITGSSKTSRGGGGSGAGEPPKSTPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCN--HDAPGKMAAATVSNVYSQTNGAQPPPLGGMPVGQLPQAPPKVVVRNELMDFSTSLARACDSSSSSSLGSGEAAGLSRG---PWRLPPPAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSARGHHSDREPLLG-PPATRARSLLPLPLEGKAKRSHSFDMGDFAAAAA--AAPGGYSPPRRVSNIWTKRSLSVNGMLLPF-EENDLVGARGTFGSSEWVMESTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TG9-1", "uniprot_id": "LRFN2_MOUSE", "id": "Q80TG9-1", "name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "aln": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHIGRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADDAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASLLTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGSLKGRYFWHIREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDILITTSQDSGPFTCIAANAAGEATATVEVSIVQLPHLSNSTSRMAPPKSRLSDITGSSKTSRGGGGSGAGEPPKSTPERAVLVSDVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCN--HDTPGKMAAATVSNVYSQTNGSQPPPLGGIPVGQLPQAPPKVVVRNELMDFSTSLARACDSSSSSSLGSGEAAGLGRG---PWRLPPPAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSSRGHHSDREPLLG-PPATRARSLLPLPLEGKAKRSHSFDMGDFAAAAA--AVPGGYSPPRRVSNIWTKRSLSVNGMLLPF-EESDLVGARGTFGSSEWVMESTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULH4-1", "uniprot_id": "LRFN2_HUMAN", "id": "Q9ULH4-1", "name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "aln": "METLLGGLLAFGMAFAVVDACPKYCVCQNLSESLGTLCPSKGLLFVPPDIDRRTVELRLGGNFIIHISRQDFANMTGLVDLTLSRNTISHIQPFSFLDLESLRSLHLDSNRLPSLGEDTLRGLVNLQHLIVNNNQLGGIADEAFEDFLLTLEDLDLSYNNLHGLPWDSVRRMVNLHQLSLDHNLLDHIAEGTFADLQKLARLDLTSNRLQKLPPDPIFARSQASALTATPFAPPLSFSFGGNPLHCNCELLWLRRLERDDDLETCGSPGGLKGRYFWHVREEEFVCEPPLITQHTHKLLVLEGQAATLKCKAIGDPSPLIHWVAPDDRLVGNSSRTAVYDNGTLDIFITTSQDSGAFTCIAANAAGEATAMVEVSIVQLPHLSNSTSRTAPPKSRLSDITGSSKTSRGGGGSGGGEPPKSPPERAVLVSEVTTTSALVKWSVSKSAPRVKMYQLQYNCSDDEVLIYRMIPASNKAFVVNNLVSGTGYDLCVLAMWDDTATTLTATNIVGCAQFFTKADYPQCQSMHSQILGGTMILVIGGIIVATLLVFIVILMVRYKVCN--HEAPSKMAAA-VSNVYSQTNGAQPPPPSSAPAGAPPQGPPKVVVRNELLDFTASLARASDSSSSSSLGSGEAAGLGRA---PWRIPPSAPRPKPSLDRLMGAFASLDLKSQRKEELLDSRTPAGRGAGTSARGHHSDREPLLG-PPAARARSLLPLPLEGKAKRSHSFDMGDFAAAAAGGVVPGGYSPPRKVSNIWTKRSLSVNGMLLPF-EESDLVGARGTFGSSEWVMESTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5V0-1", "uniprot_id": "A0ACD6B5V0_DANRE", "id": "A0ACD6B5V0-1", "name": "Leucine-rich repeat and fibronectin type-III domain-containing protein 2", "aln": "MDHGLCQMLVLGMVAVMARACPKYCACQNLSESLGTLCPAKGLLFVPSDIDRSTVELRLGGNFILRITQQDFANMTDLVDLTLSRNTISYIQPFSFGDLETLRSLHMDNNRLTELGPDDLRGLISLQHLILNNNQLSRVSERAFEDLAATLEDLDLSYNNLQALPWHSVRQMINLHQMSLDHNLLDYIPEGTFVDLERLARLDLTSNRLQKLPPDPIFARAQDSEVMTTPFAPQLSLSIGGNPLHCNCELLWFRRLERDDDLETCASPPGLKGRYFWNVREHEFLCEQPLITQHTHKLLVLEGQTASLRCDAIGDPIPTIHWVTPEDRLLGNSSRTVVYRNGTLEILITTSKDSGTFTCIAANLAGESTASVELSIIQLPHISNGTGQASQPKSRLSDITGGSRTNKG--------IPKGQPEKAVSVSEVTAVAALVRWTVGKTAPKVKMFQLQYNCSDDEVLIYRMIPSSSKAFHITNLVSGTRYDLCVLAAWEDSATTLTATNVVGCVEFYTRDDYTQCQSLQGQLLGGTMILVVGGVIVATLLVFIVILMVRYKAGDGGGDAP-VCKLSDSSETYSQTNGGRLGQ-NGVPLPG-PKEKSTVTMRDEVVKFKCGSLQSSSSSSSSSSGSADATSYSPNSALANILRSAPPKQHNNIDQLLGAFTSLELRGQSKD-LCLSGTPSSAAAPAVSPAGPADKEPLLGRTLDSRLSKLLMLPLDSKPKRSHSFDMGDFTVPTA----QQLRSYPRRFSSIWTKRSLSVNGTLLPCDEEADSNGSKGTIESPEWVMESTV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 505, "similar_positions": 179, "identity": "63.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-117", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96SB3-1", "uniprot_id": "NEB2_HUMAN", "id": "Q96SB3-1", "name": "Neurabin-2", "aln": "MMKTEPRGPGGP-----LRSASPHRSAYEAG-IQALKPP-----DAPGPDEAPKGAHH-KKYGSNVHRIKSMFLQMGTTAGPSGEAGGGAGLAEAPRASERGVRLSLPRASSLNENVDHSALLKLGTSVSERVSRFDSKPAPSAQPAPPPHPPSRLQETRKLFERSAPAAAGGDKEAAARRLLRQERAG-LQDR-KLDVVVRFNGSTEALDKLDAD-----AVSPTVSQLSAVFEKADS-RTGLHRGP-----GLPRAAGVPQVNSKLVSKRSRVFQPPPPPPPAPSGDAPAEKERCPAGQQPPQHRVAPARPPPKPREVRKIKPVEVEESGESEAESAPGEVIQAEVTVHAALENGSTVATAASPAPEEPKAQAAPEKEAAA-VAPPERGVGNGRAPDVAPEEVDE-SKKEDFSEADLVDVSAYSGLGEDSAGSALEEDDEDDEEDGEPPYEPESGCVEIPGLSEEEDPAPSRKIHFSTAPIQVFSTYSNEDYDRRNEDVDPMAASAEYELEKRVERLELFPVELEKDSEGLGISIIGMGAGADMGLEKLGIFVKTVTEGGAAHRDGRIQVNDLLVEVDGTSLVGVTQSFAASVLRNTKGRVRFMIGRERPGEQSEVAQLIQQTLEQERWQREMMEQRYAQYGEDDEETGEYATDEDEE--LSPTFPGGEMAIEVFELAENEDALSPVDMEPEKLVHKFKELQIKHAVTEAEIQQLKRKLQSLEQEKGRWRVEKAQLEQSVEENKERMEKLEGYWGEAQSLCQAVDEHLRETQAQYQALERKYSKAKRLIKDYQQKEIEFLKKETAQRRVLEESELARKEEMDKLLDKISELEGNLQTLRNSNST", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6R891-1", "uniprot_id": "NEB2_MOUSE", "id": "Q6R891-1", "name": "Neurabin-2", "aln": "MMKTEPRGPGGP-----LRSASPHRSAYEAG-IQALKPP-----DAPGPDEAPKAAHH-KKYGSNVHRIKSMFLQMGTTAGPPGEAGGGAGMAEAPRASDRGVRLSLPRASSLNENVDHSALLKLGTSVSERVSRFDSKPAPSAQPAPPPHPPSRLQETRKLFERSVPAASGGDKEAVARRLLRQERAG-LQDR-KLDVVVRFNGSTEALDKLDAD-----AVSPTVSQLSAVFEKADS-RTGLHRAP-----GPPRAAGAPQVNSKLVTKRSRVFQPPPPPP-APSGDGATEKERGPGGQQPPQHRVAPARPPPKPREVRKIKPVEVEESGESEAESAPGEVIQAEVTVHAALENGSTPATTASPAPEEPKAEAVPEEEAAASVATLERGVDNGRAPDMAPEEVDE-SKKEDFSEADLVDVSAYSGLGEDSGGSALEEDDEEDEEDGEPPYEPESGCVEIPGLSEEEDPAPSRKIHFSTAPIQVFSTYSNEDYDRRNEDVDPMAASAEYELEKRVERLELFPVELEKDSEGLGISIIGMGAGADMGLEKLGIFVKTVTEGGAAHRDGRIQVNDLLVEVDGTSLVGVTQSFAASVLRNTKGRVRFMIGRERPGEQSEVAQLIQQTLEQERWQREMMEQRYAQYGEDDEETGEYATDEDEE--LSPTFPGGEMAIEVFELAENEDALSPVEMEPEKLVHKFKELQIKHAVTEAEIQQLKRKLQSLEQEKGRWRVEKAQLEQSVEENKERMEKLEGYWGEAQSLCQAVDEHLRETQAQYQALERKYSKAKRLIKDYQQKEIEFLKKETAQRRVLEESELARKEEMDKLLDKISELEGNLQTLRNSNST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B7D6-1", "uniprot_id": "A0ACD6B7D6_DANRE", "id": "A0ACD6B7D6-1", "name": "", "aln": "MMKTESSSSSKPASSTSLRSPSPHRNAYEAAGIQALKPANDILNNGDAQDGKPKSTSRGRTYGSNVHRIKNMFMQMGASSPTEAED------PQRANGDGKAVRLTLPRAGSLNENVDHSALLKLGSSVSERVNRFDGKSDAS------PCRYSKLQETRKIFEQNQEKQAASN-----RVLLKKERAAGFQDASRLDVVARFNGSTESLDSLDAIGGTGEAVSPTVSQLSAVFERAAELRNNLHRLSNTPPLPLPLRGRVGALNSKIISKRARAFPPG-----ANREDGVNQHQEEQDGRFSSLNGASELQDS--------LSSVEEKQTG---DECSASEFATQDSKCKQEQAN----ATEAKGTLISADLHSFGNSGVSSNGEAVERDAEDGRSVGVSKTEDDDGTQQKGFSTADLVDISAYSAVGEDSAGSQLEDEEEEDEE-----YEPESSCSEIPGLPAEEEPPPSRKIKFSVQPIKVFTTYSNEDYDRRNDDVDPMAASAEYELEKRVERLDLFPVELEKDNEGLGISIIGMGAGADMGLEKLGIFVKTVTDGGAAHRDGRIQVNDLIVEVDGTSLVGVTQSFAASVLRNTSGTVRFIIGREKPGEQSEVAQLIQQTLEQERWQREMMEQRYRNYMGDEEEPGDYGTDEEEEDEMSPTYPS---AIEVFDLAENEDMLSPVEVDPEKLAHKYKELQIKHAVTQAEIQQLKRKLNHAEQDKQRWRSEKAQMERNMQENRERMEKLEGYWMEAQSLCQAVDEHLKETQAQYQALERKYSKAKRLIKEYQQKEIELLKKKTAQQQTVEETEASQNEETEQLQDKVTDLESQVEEVKSLDPS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****. ... * ***.****.****. ******. :. . * **.: : :.*********.**:***::: . .* .: .... :.***:****.***************:******.***.*. .* * *:******:**:. :..: * **::***. :** :****.*******:**.*** **************:* . *..*** . * . . :***:::**:*.* * * *. :::. *: .. : .: : . :..** :::* *.:..*. : . : * ** *. : ... .: :. .:: . **.. :**: .:: * *: ::::.** *****:****.:****.** **:::*:*** *****.* *****. **:*.*****:**. **:**:***********:********************:*********.*****************************:***************:***********************.* ***:****:***************************** :* *:**.*:*.***:** :***:*. *****:****** ****:::****.**:**********:**********: **:* *** ****:*:.::**:********** *************:*********************:*******:***:***::.:**:* :::** ::* **:::**.::: ::. :.:", "identical_positions": 482, "similar_positions": 195, "identity": "56.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-128", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88954-1", "uniprot_id": "MPP3_RAT", "id": "O88954-1", "name": "MAGUK p55 subfamily member 3", "aln": "--MPVLSEDSGLHETLALLTSQLRPDSNHR--EEMGFLRDVFSEKSLGYLMKIHEKLRYYERQS-PTPVLHSAMALAEDVMEEL-QAASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDNIDEDFEEESVKIVRLVKNKEPLG----------ATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGITVLHKRPDEISQILAQSQGSITLKIIPATQEEDRFKESKVFMRALFHYDPREDRAIPCQEAGLPFQQRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKQFQERRLSYRRTTGTIPSPQNLRKPLYDQPCDKETCDCDGYFKG------------------------HYVAGLRRSFRLGCRERLTGSQEVKVPVGAESQVLLTYEEVARYQHQPGERSRLVVLIGSLGAHLHELKQRVVAEDPQHFGVAVPHTTRPRKSHEREGVEYHFVSKQAFEADIQHNKFLEHGEHKENLYGTSLEAIQTVMAKNKVCLVDVEPEALRHLRTPEFKPYVIFVKP----AIQEKR--KTPPVSPDSEDPATPLDEQQQEMAASAAFIDQHYGHLIDTVLVRQDLQSVCSQLRAVIESLSKDTYWVPISWVR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88910-1", "uniprot_id": "MPP3_MOUSE", "id": "O88910-1", "name": "MAGUK p55 subfamily member 3", "aln": "--MPVLSEDSGLHETLALLTSQLRPDSNHR--EEMGFLRDVFSEKSLSYLMKIHEKLRYYERQS-PTPVLHSAMALAEDVMEEL-QAASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDNIDEDFEEESVKIVRLVKNKEPLG----------ATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRFKDSKVFMRALFHYDPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKQFQERRLSYRRTTGTLPSPQNFKKPPYDQPCDKETCDCDGYFKG------------------------HYVAGLRRSFRLGCRERLGGSQEAKVPTGAESQVLLTYEEVARYQHQPGERPRLVVLIGSLGAHLHELKQRVVAEDPQQFAVAVPHTTRPRKSHERDGVEYHFVSKQAFEADVHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALRHLRTPEFKPYVIFVKP----AIQERR--KTPPVSPDSEDIASSLDEQQQEMAASAAFIDQHYGHLIDTVLVRQDLQEPAASS-----ELS-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13368-1", "uniprot_id": "MPP3_HUMAN", "id": "Q13368-1", "name": "MAGUK p55 subfamily member 3", "aln": "--MPVLSEDSGLHETLALLTSQLRPDSNHK--EEMGFLRDVFSEKSLSYLMKIHEKLRYYERQS-PTPVLHSAVALAEDVMEEL-QAASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDNIDEDFDEESVKIVRLVKNKEPLG----------ATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESKVFMRALFHYNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKGFQERRLSYRRAAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKG------------------------HYVAGLRRSFRLGCRERLGGSQEGKMSSGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFVSKQAFEADLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFVKP----AIQEKR--KTPPMSPACEDTAAPFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDTHWVPVSWVR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U0N5-1", "uniprot_id": "A0AB32U0N5_DANRE", "id": "A0AB32U0N5-1", "name": "", "aln": "--MPVLSPTTGLHEMLALLTSQLHPEANHK--EDLVFLREVFSERSLSYLMKIHERLRQFHLYS-PTPVLHSASCLAEDVAEEL-QNGSLEEDERELLALLSTPHIKAVLTVHDTVAQKNFEPVLPPLPNDLEDELEEESVKIVRLVKNKEPLG----------ATIRRDEVTGAVVVARIMRGGAADRSGLVHVGDELREVNGNLIIHKRPEEISQILSQSQGSITLKIIPAIKEEDRFKESKVYLRALFDYTPYEDRATPCQEAGLPFLCGDVLQVVSQDDPTWWQAKRVGDSNLRAGLIPSRQFQERRLLYRMKMGTHQSPKSPRATPCDQTCEKEDCDSESSVSGQHVVVVSPKCKAVAPSCGQAFSWEFYSAGLRRSFRLSRKDHQGSNKESHTPESTEN-EFLIYEEVTLHQMRLQDKPRLVVLIGSLGARINELKQKVIAENPQRYGVAVPHTTRPRKSHEKEGVEYHFISKQAFDADIQSNKFIEYGEYKNNQYGTSLESIRSVLARNKVCLVDVQPEALKILRTSEFKPYVIFVKP----RIPEIRRHRSSPTSPERGDNGHITEEDLLDMKHSAEQMEQQYGHLVDRVLIKEDSASACVELRLILERLEREPQWVPVSWVRS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z8G0-1", "uniprot_id": "A1Z8G0_DROME", "id": "A1Z8G0-1", "name": "", "aln": "MLEAVMASDINWDPALSKLISTLKESENLSNDQEIDFLKALLESKELNALVNVHTKVAKVGRDDRLAPVLSTSAQVLYEVLEQLSQHCHLNDDCKEAFHLLQDSHLQHLLFAHDAIAQKDFYPHLPEAPVEMDE--DEETIKIVQLVKSNEPLTGAQSTEPIVGATIKTDEESGKIIIARIMHGGAADRSGLIHVGDEVIEVNNINVEGKTPGDVLTILQNSEGTITFKLVPADNK-GAQRESKVRVRAHFDYNPDVDPYIPCKEAGLAFQRGDVLHIVAQDDAYWWQARKEHERSARAGLIPSRALQERRILHDRTQKNGTDLDS-KPGSCASLCTTPPGSPRLPASS-------------------------STSSCRQPKTKKIMYDLTENDD------FDREQIATYEEVAKLYPRPG-VFRPIVLIGAPGVGRNELRRRLIARDPEKFRSPVPYTTRPMRTGEVAGREYIFVAREKMDADIEAGKFVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRTAQLKPFLIHVKPPELDILKATRTEARAKSTFDEANARSFTDEEFEDMIKSAERIDFLYGHFFDVELVNGELVNAFEQLVQNVQRLENEPVWAPSMWVQ-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*:: . . *: * * *: . * ::: **: ::..:.*. *:::* :: . :*** :: : :* *:* * :..* :* : **. .*:: :* .**::***:* * ** * :::: :**::***:***.:*** ***: ** :* :::****:*********:*****: ***. : * * :: ** :*:*:**:*::** :: . ::*** :** *.* * * **:****.* :**.:*:***. ****:: : . *******: :****: : . . .. : . * . . .. :. *:. ..: : : ****: : * :****: *. :**:::::*.:*::: .**:**** :: * * ** *:::: ::**:. .**:*:**:* : **** *:::::: . **::. . :*:: ***.::**::*.*** : * . : : :*: :* ** :: ***:.* *:. : . *. ", "identical_positions": 183, "similar_positions": 183, "identity": "28.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-14", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M918-1", "uniprot_id": "F1M918_RAT", "id": "F1M918-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------MKTEDEEMEDQLSK------------------------------------------------------------------------------------------EEIVSEDKEFD----YRTIIKENFFIIWDKTSLLGESATLNCVTTHKDQ-------------------------------KLLEHIFDVNIQTSKSPQTVVLYGAAGIGKTTLLKKAVLEWADGNLYQQ-FTHVFYLSGREIS-QEKEKNFAQLISKHWPSSEGPIEQILCKPSSLLFILDSFDELDFSFEEPEFA----LCRDWTQKHPVSFLISSLLRKVMLPESYLLVTTRTTAWKRLVPLLQKPHRVKLPGLSRSSRIDYIHHLLKDKTWAMNAVCSIRMNAKLFNMCHVCHVCQMICTFLKEQVEKGGNVEMTCQTSTALFTYYICSLFPRIAGSSVTLPNETLLRSLCQAAVEGIWTMKHVLYQQNLRKHELTREDLSLFLEANVLQQDTEC----ENCYTFTHLQVQEYFAALFYLLRENPE------EKDHPLEPFENVHLLLES--NHFHDPHLEQMKCFLFGLLNKDRVQQLEETFNLTISRAVREELLVCLEALEKDDSPLSQLRIQDLLHCIYETQDEEFITQALTYFQKIMVK-VDEESKLLIYSYCLKHCHSLQTVRLTARADLRNMLDP---TAEICLED----------AAVRIIHYWQDLFSVLHTNESLLEMDLYESRLDESLMKILNEEFSHPKCNLQKVMFRAVCFL-NSCYDFS-FLAFNNTVTHLDLKDTDLGDNGVKTLCEALKYQGCKLRVLRLESCDLNVTHCQNLSKALQSNRSLVFLNLSTN-SLSNDGVKSLCEVLENPNCPLERLALASCGLTKVGCEVLSSALTKT-KRLTHLCLAHNVLEDEGIELLSYTLRHPRCTLQSLVLRCCYFTPIGSEHLSTALQNN-KSLIHLDLGFNKLADSGVKLLCQTLQQPNCNLQELELMGCVLTSEACGDLASVLVNN-SNLWNLDLGNNILDDAGLNILCEALRNPNCQIRRLGLENCGLTPGCCQDLLDLLSN-NQSVIQMNLMKNSLDYEAIRNLCKVLRSPTCKMEFLALDKKDLFKKKIKKFLVDVRINNPHLVIRPQCP--NTESGCWWQYF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6B966-1", "uniprot_id": "NAL14_MOUSE", "id": "Q6B966-1", "name": "NACHT, LRR and PYD domains-containing protein 14", "aln": "----------------------------------------------------------------------------------------------------------------------------------MKTEDDEMEYEASK------------------------------------------------------------------------------------------EETVSEDKDFDDGIDYRTVIKENIFTMWYKTSLHGEFATLNCVITPKDQ-------------------------------NLLQHIFDEDIQTSEAPQTVVLQGAAGIGKTTLLKKAVLEWADGNLYQQ-FTHVFYLNGKEIS-QVKEKSFAQLISKHWPSSEGPIEQVLSKPSSLLFIIDSFDELDFSFEEPQFA----LCKDWTQISPVSFLISSLLRKVMLPESYLLVATRSTAWKRLVPLLQKPQRVKLSGLSKNARMDYIHHLLKDKAWATSAIYSLRMNWRLFHMCHVCHMCQMICAVLKGQVEKGGRVEETCKTSTALFTYYICSLFPRIPVGCVTLPNETLLRSLCKAAVEGIWTMKHVLYQQNLRKHELTREDILLFLDAKVLQQDTEY----ENCYMFTHLHVQEFFAALFYLLRENLE------EQDYPSEPFENLYLLLES--NHIHDPHLEQMKCFLFGLLNKDRVRQLEETFNLTISMEVREELLACLEGLEKDDSSLSQLRFQDLLHCIYETQDQEFITQALMYFQKIIVR-VDEEPQLRIYSFCLKHCHTLKTMRLTARADLKNMLD----TAEMCLEG----------AAVQVIHYWQDLFSVLHTNESLIEMDLYESRLDESLMKILNEELSHPKCKLQKLIFRAVDFL-NGCQDFT-FLASNKKVTHLDLKETDLGVNGLKTLCEALKCKGCKLRVLRLASCDLNVARCQKLSNALQTNRSLVFLNLSLN-NLSNDGVKSLCEVLENPNSSLERLALASCGLTKAGCKVLSSALTKS-KRLTHLCLSDNVLEDEGIKLLSHTLKHPQCTLQSLVLRSCSFTPIGSEHLSTALLHN-RSLVHLDLGQNKLADNGVKLLCHSLQQPHCNLQELELMSCVLTSKACGDLASVLVNN-SNLWSLDLGHNILDDAGLNILCDALRNPNCHVQRLGLENCGLTPGCCQDLLGILSN-NKSVIQMNLMKNALDHESIKNLCKVLRSPTCKMEFLALDKKEILKKKIKKFLVDVRINNPHLVIGPECP--NTESGCWWNYF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86W24-1", "uniprot_id": "NAL14_HUMAN", "id": "Q86W24-1", "name": "NACHT, LRR and PYD domains-containing protein 14", "aln": "------------------------------------------------------------------------MADSSSSSFFPDFGLLLYLEELNKEELNTFKLFLKE-------TMEPEHGLTP-WNEVKKARREDLANLMKKYYPGEKAWSVSLKIFGKMNLKDLCERAKEEINW--------------------------------------------SAQTIGPDDAKAGETQEDQEAVLGDGTEYRNRIKEKFCITWDKKSLAGKPEDFHHGIAEKDR-------------------------------KLLEHLFDVDVKTGAQPQIVVLQGAAGVGKTTLVRKAMLDWAEGSLYQQRFKYVFYLNGREIN-QLKERSFAQLISKDWPSTEGPIEEIMYQPSSLLFIIDSFDELNFAFEEPEFA----LCEDWTQEHPVSFLMSSLLRKVMLPEASLLVTTRLTTSKRLKQLLKNHHYVELLGMSEDAREEYIYQFFEDKRWAMKVFSSLKSNEMLFSMCQVPLVCWAACTCLKQQMEKGGDVTLTCQTTTALFTCYISSLFTPVDGGSPSLPNQAQLRRLCQVAAKGIWTMTYVFYRENLRRLGLTQSDVSSFMDSNIIQKDAEY----ENCYVFTHLHVQEFFAAMFYMLKGSWE------AGNPSCQPFEDLKSLLQS--TSYKDPHLTQMKCFLFGLLNEDRVKQLERTFNCKMSLKIKSKLLQCMEVLGNSDYSPSQLGFLELFHCLYETQDKAFISQAMRCFPKVAIN-ICEKIHLLVSSFCLKHCRCLRTIRLSVTVVFEKKILK---TSLPTNTW----------DGDRITHCWQDLCSVLHTNEHLRELDLYHSNLDKSAMNILHHELRHPNCKLQKLLLKFITFP-DGCQDISTSLIHNKNLMHLDLKGSDIGDNGVKSLCEALKHPECKLQTLRLESCNLTVFCCLNISNALIRSQSLIFLNLSTN-NLLDDGVQLLCEALRHPKCYLERLSLESCGLTEAGCEYLSLALISN-KRLTHLCLADNVLGDGGVKLMSDALQHAQCTLKSLVLRRCHFTSLSSEYLSTSLLHN-KSLTHLDLGSNWLQDNGVKLLCDVFRHPSCNLQDLELMGCVLTNACCLDLASVILNN-PNLRSLDLGNNDLQDDGVKILCDALRYPNCNIQRLGLEYCGLTSLCCQDLSSALIC-NKRLIKMNLTQNTLGYEGIVKLYKVLKSPKCKLQVLGLCK-EAFDEEAQKLLEAVGVSNPHLIIKPDCNYHNEEDVSWWWCF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3TKR3-1", "uniprot_id": "NAL4C_MOUSE", "id": "Q3TKR3-1", "name": "NACHT, LRR and PYD domains-containing protein 4C", "aln": "-----------------------------------------------------------------------------MASFFSDFGLMWYLEELNKKEFMKFKEFLKQ-------EILQLRLKQISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRKD--------------------------------------------------------------------LMERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKVQDFSKQKFTQDDY-------------------------------DRFENFLIS-KVTAKKPHMVFLQGAAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVK-KMKRASLAELISKEWPKTSAPIEDILSQPEKLLFVIDNLEVMECDMSERESE----LCDTCTEKQPVRILLSSLLRRKMLPKSSFLISATPETFEKMEGRVECTNVKIVTGFNESNIKMYFRSLFQDKTKTQEIFSLVKENQQLFTVCQVPVLCWMVATCLKKEIEKGRDLVSVCRRTTSLYTTHIFNLFIPQSAQYPSKESQAQLQSLCSLAAEGMWTDTFVFGEEALRRNGIMDSDIPTLLDVRILEKSKKS----EKSYIFLHPSIQEVCAAIFYLLKSH---------MDHPSQDVKSIEALIFT-FLKKVKVQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNEELQEQVDGMKLFYCLFEMDDEAFLAQAMNCMEQINFV-AKDYSDVIVAAHCLQHCSTLKKLSLSTQNVLS---------EGQEHS-----------YTEKLLMCWHHMCSVLISSKDIYILQVKNTNLNETASLVLYSHLMYPSCTLKALVVNNVTFL-CDNRLFFELIQNQ----------------------------------------------------------CLQHLDLNLT-FLSHGDVKLLCDVLSQEECNIEKLMVAACNLSPDDCKVFASVLISS-KMLKHLNLSSNNL-DKGISSLSKALCHPDCVLKNLVLVNCSLSEQCWDYLSEVLRRN-KTLNHLDISSNDLKDEGLKVLCGALSLPDSVLKSLSVRYCLITTSGCQDLAEVLRKN-QNLRNLQVSNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASAFTH-CKTLWGINLQENALDHSGLIVLFEALKQQQCTLHVLGLRI-TDFDKETQELLMAEEEKNPHLSILSSV---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66X19-1", "uniprot_id": "NAL4E_MOUSE", "id": "Q66X19-1", "name": "NACHT, LRR and PYD domains-containing protein 4E", "aln": "-----------------------------------------------------------------------------MASFFSDFGLMWYLEELNKKEFMKFKELLQQ-------EILQLGLKHISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRQD--------------------------------------------------------------------LMERAGREIAGHSKLYQVHLKKKLTHDYARKFNIKDQDSLKQKFTQDDC-------------------------------DHFENLLIS-KATGKKPHMVFLQGVAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVK-KMKRASLAELISKEWPNASAPIEEILSQPEKLLFVIDNLEVMECDMSEWESE----LCDDCMEKQPVNILMSSLLRRKMLPESSFLVSATPETFEKIEDRIECTNVKMMAGFNESSIKVYFYSLFQDRNRTQEIFSLVRENEQLFSVCQVPVLCWMVATCLKKEIEKGRDPVSICRRITSLYTTYIFNLFIPHSAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFAEEALRRNGIMDSDISTLLDVRILEKSKES----EKSYIFLHPSIQEVCAAIFHLLKSH---------VDHPSQDVKSIEALIFT-FLKKVKIQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNKELQEQIDGMKLFYCLFEMDDEAFLPQVMNCMEQIKFV-AKDYSDVIVAAHCLQHCSTLKKLSLSTQNILS---------EGQEHS-----------YTEKLLICWHHVCSVLTSSKDIHVLQVKDTNFNERAFLVLYSHLKYPSCILKVLEVNNVTLL-CDNRLLFELIQNQ----------------------------------------------------------RLQLLNLSLT-FLSHNDVKLLCDVLNQAECNIEKLMVADCNLSPDDCKVFVSVLISS-KMLKHLNLSSNNL-DKGISSLSKALCHPDCVLKNLVLAKCSLSEECWHYLSEVLRRN-KTLTHLDISFNDLKDEGLKVLCGALTLPDSVLISLSVRYCLITTSGCQDLAEVLRNN-QNLRNLQISNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASSFTH-CKTLLGINLQENALDHSGLVALFEAMKQQQCTVNLRGLRI-TDFDKETQEFLMAEKEKNPYLSI-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZP31-1", "uniprot_id": "D3ZP31_RAT", "id": "D3ZP31-1", "name": "", "aln": "-----------------------------------------------------------------------------MASFFSDFGLMWYLEELNKKEFVKFKEFLKQ-------EILQLRLKQISWTKVKKASREDLANLLLKHYEEKQAWDMTFKIFQKMNRKD--------------------------------------------------------------------LIERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKAQDLFKQKFTQDDC-------------------------------DRFENLLVS-KATGKKPHMVFLQGVAGIGKSLMLTKLMLAWSEGIVFQNKFSYIFYFCCQDVK-QLKRASLAELISREWPNASAPTAEILSQPEKLLFIIDSLEVMECNMSERESE----LCDNCTEKQPVSLLLSSLLRRKMLPESSFLISATPETFEKMEDRIECTNVKIITGFNENNIKMYFRSLFQDKNRTLEAFSLVRENEQLFNVCQVPVLCWMVATCIKKEIEKGRDPVFICRRTTSLYTTHIFNLFTPQNAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFSEEALRRNGILDSDIPTLLDRRILERSKES----ESCYIFLHPSLQEVCAAVFYLLKSH---------LDHPSQDVKSVEALLFT-FLKKAKVQWIFLGCFLFGLLHESEQEKLEMFFGHQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEAFLMQAMNCMEQINFV-AKDYSDVIVAAYCLKHCSTLKKLSFSTQNILS---------EEQEHS-----------YTEKLLICWHHMCSVLISSKDIHVLQVKDTNLNETAFWVLYNHLKYPSCTLKVLVVNNVTFL-CDNHLFFELIQNQ----------------------------------------------------------RLQHLNLSLT-FLSHSDVKLLCDVLNQAECNIEKLMIAACNLSPDDCKVFASVLISS-KMLKHLNLSSNNL-DKGISSLCKALCHPDCILKHLVLANCSLSEQCWDYLSEVVRRN-KTLSHLDISSNDLKDEGLKVLCGALTLPDSGLISLSVRHCLITTSGCQDLAEVLRHN-QNLRSLQVSNNKIEDAGVKLLCDAIKQPNCHLENIGLEACELTGACCKDLASAFVH-CKTLWGINLLENALDHSGLVVLFEALKQQKCTLHVLGLRI-TDFDKETQEFLIAEEEKNPYLSILSNV---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZUH1-1", "uniprot_id": "D3ZUH1_RAT", "id": "D3ZUH1-1", "name": "", "aln": "-----------------------------------------------------------------------------MASFFSDFGLMWYLEELNKKEFMKFKEFLKQ-------EILQLGLKQVSWTEVKKASREDLASLLLKHYEEKQAWDMTFNFFQKINRKD--------------------------------------------------------------------LIKRAKREIDGYPKLYRAHLKTKLTHDSSRIFNINIQDFLKEKFTKDDH-------------------------------DRFETLLQS-KGTESKPQVVVLSGVAGIGKTLMLKRLMLAWIEGLVFPYKFSYIFYFCCQEVK-QLKTASLAELISREWPDPSAPIEEILSEPEKLLFIIDSLEGIECDLFKCDSE----LCDNCMEKQPVNILLSSLLRKKMLLEASLLISTTPETFEKMEDRIEYTHVKIITGLNESDIKMCFHRLFQDRNRAQEAFSLVRENEQMLTICQVPVLCWMVATCLKTEIEKGRNLVSTCRRTTSLYTTYIFNLFIPQSAHSPSKKSQDQLQGLCSLAAEGIWTDTFVFTEEALRRNGILDSDIPTLLDIGMLGKMGKF----ENCYIFLHPSLQEACAAIFYLLKSH---------GDHPIEDVKSVEALLFT-FLKKAKVQWILGGRFIFGLLHESEQKKLEAFFGHQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEDFLMEAMNYMEQINFV-AKDYSDVIVAAYCLKHCYTLKKLSFSTQNILN---------EEHEHS-----------CMENLLTCWRHICSVLINSKDIQELQIKDTNLNEPAFSVLYNSLKYCNDTLKVLVENNVFFL-CEKYLFFELIQNC----------------------------------------------------------NLQHLNLNLT-FLSHSDVKLLCDVLNQAECNIEKLEVAACNLSPDDCKMFASILMSS-KTLKQLNLSSNIL-GKGISSLCKSLCHPDCILEHLVLAKCSLSDQCWDYLSDGIRQN-KTLNHLDISSNDLKDEGLKVLCRALALPNSVLKSLCLRHCLITTSGCQDLAEVLRNN-QNLTSLQISYNKIEDAGVKLLCDAIKQPNCHLEDLGLEACELTGACCEDLASTFTQ-CRTLWGINLLNNTLDYTGLVVLCEALRQQKCTPHVLGLRI-TDFDNETQAFLVAEQEKNPDLSILSGV---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BU40-1", "uniprot_id": "NAL4A_MOUSE", "id": "Q8BU40-1", "name": "NACHT, LRR and PYD domains-containing protein 4A", "aln": "-----------------------------------------------------------------------------MASFFSDFGLMWYLEELNKKEFVKFKEFLKQ-------EVLQLGLKQVSWTEVKKASRQDLASLLLKHYEEKPAWDMTFRFFQKINRKD--------------------------------------------------------------------LIERAKREIDGCPKLYRAHMKTKMTHDSSRAFTISIQNFLKEKFTEDDY-------------------------------DCFENLFQS-KGTESKPQVVFLSGGAGVGKTLMLKRLMLAWIESPVFLHKFSYIFYFCCREVK-QLKTASLAELISREWPGPSAPIEEILSKPEKLLFIIDSLEGMECDLFKWESE----LCDNCTEKQPVNVLLSSLLRRKMLPESSLLISATPESFEKMENRIEYTHVKIIKGLKERNIKMSFHRLFQDRNRAHEAFSLVRENEQLFTVCQVPVLCWMVATCLKEEIEKGRDPVSICRCTTSLYTTHIFNLFIPQNAHSPSKKSQDQLQGLCSLAAEGMWTDTFVFGEEALRRNGIMDSDIPILLDIGMLINIRES----EKSYIFLHPSVQEVCAAIFYLLKSH---------VDHPSQEVKSIEKLMFA-FLKKVKVQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNEELQEQIDGMKLFYCLFEMDDDTFLVEAMNCMEQINFV-AKDYSDVIVAAHCLKHCFTLKKLSFSTQNVLS---------GAQEHS-----------YMERLLTAWNHICSVFIISKDIQELRMKDTNLSESAFSVLYNNLKYHNYTLNVLVANNVFFV-CEKYLFFELIQNC----------------------------------------------------------NLQHLNLSLT-ILSHSDVKLLCDVLSQAECNIEELVVAACSISSDDCKVFASVLISN-KTLKHLNLASNTL-DKGIASLCKSLCHPDCILEHLVLANCSLNEKCWDYLSEVLRRN-KTLSHLDISSNDLKDEGLKVLCRALTLPDSVLKSLSLRHCLITISGCQDLAEVLRNN-QNLVSLQVSNNKLEDTGVKLLCDAIKHPNCHLEDLGLEACELTGACCEDLASTFTQ-CKTLWAMNLLKNALDYNGLVVLCEALKQQTCATYVLGLQI-TDFDTETQAFLVAEQEKNPCLRILSSL---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96MN2-1", "uniprot_id": "NALP4_HUMAN", "id": "Q96MN2-1", "name": "NACHT, LRR and PYD domains-containing protein 4", "aln": "----------------------------------------------------------------------------MAASFFSDFGLMWYLEELKKEEFRKFKEHLKQ-------MTLQLELKQIPWTEVKKASREELANLLIKHYEEQQAWNITLRIFQKMDRKD--------------------------------------------------------------------LCMKVMRERTGYTKTYQAHAKQKFSRLWSSKSVTEIHLYFEEEVKQEEC-------------------------------DHLDRLFAP-KEAGKQPRTVIIQGPQGIGKTTLLMKLMMAWSDNKIFRDRFLYTFYFCCRELR-ELPPTSLADLISREWPDPAAPITEIVSQPERLLFVIDSFEELQGGLNEPDSD----LCGDLMEKRPVQVLLSSLLRKKMLPEASLLIAIKPVCPKELRDQVTISEIYQPRGFNESDRLVYFCCFFKDPKRAMEAFNLVRESEQLFSICQIPLLCWILCTSLKQEMQKGKDLALTCQSTTSVYSSFVFNLFTPEGAEGPTPQTQHQLKALCSLAAEGMWTDTFEFCEDDLRRNGVVDADIPALLGTKILLKYGER----ESSYVFLHVCIQEFCAALFYLLKSH---------LDHPHPAVRCVQELLVANFEKARRAHWIFLGCFLTGLLNKKEQEKLDAFFGFQLSQEIKQQIHQCLKSLGERGNPQGQVDSLAIFYCLFEMQDPAFVKQAVNLLQEANFH-IIDNVDLVVSAYCLKYCSSLRKLCFSVQNVFK---------KEDEHSS----------TSDYSLICWHHICSVLTTSGHLRELQVQDSTLSESTFVTWCNQLRHPSCRLQKLGINNVSFS-GQSVLLFEVLFYQP---------------------------------------------------------DLKYLSFTLT-KLSRDDIRSLCDALNYPAGNVKELALVNCHLSPIDCEVLAGLLTNN-KKLTYLNVSCNQL-DTGVPLLCEALCSPDTVLVYLMLAFCHLSEQCCEYISEMLLRN-KSVRYLDLSANVLKDEGLKTLCEALKHPDCCLDSLCLVKCFITAAGCEDLASALISN-QNLKILQIGCNEIGDVGVQLLCRALTHTDCRLEILGLEECGLTSTCCKDLASVLTC-SKTLQQLNLTLNTLDHTGVVVLCEALRHPECALQVLGLRK-TDFDEETQALLTAEEERNPNLTITDDCDTITRVEI-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7RTR0-1", "uniprot_id": "NLRP9_HUMAN", "id": "Q7RTR0-1", "name": "NACHT, LRR and PYD domains-containing protein 9", "aln": "----------------------------------------------------------------------------MAESFFSDFGLLWYLKELRKEEFWKFKELLKQ-------PLEKFELKPIPWAELKKASKEDVAKLLDKHYPGKQAWEVTLNLFLQINRKD--------------------------------------------------------------------LWTKAQEEMRNKLNPYRKHMKETFQLIWEKETCLHVPEHFYKETMKNEY-------------------------------KELNDAYT----AAARRHTVVLEGPDGIGKTTLLRKVMLDWAEGNLWKDRFTFVFFLNVCEMN-GIAETSLLELLSRDWPESSEKIEDIFSQPERILFIMDGFEQLKFNL-QLKAD----LSDDWRQRQPMPIILSSLLQKKMLPESSLLIALGKLAMQKHYFMLRHPKLIKLLGFSESEKKSYFSYFFGEKSKALKVFNFVRDNGPLFILCHNPFTCWLVCTCVKQRLERGEDLEINSQNTTYLYASFLTTVFKAGSQSFPPKVNRARLKSLCALAAEGIWTYTFVFSHGDLRRNGLSESEGVMWVGMRLLQRRGD-------CFAFMHLCIQEFCAAMFYLLKRP---------KDDPNPAIGSITQLVRA-SVVQPQTLLTQVGIFMFGISTEEIVSMLETSFGFPLSKDLKQEITQCLESLSQCEADREAIAFQELFIGLFETQEKEFVTKVMNFFEEVFIY-IGNIEHLVIASFCLKHCQHLTTLRMCVENIFP---------DDSGCIS----------DYNEKLVYWRELCSMFITNKNFQILDMENTSLDDPSLAILCKALAQPVCKLRKLIFTSVYFG-HDSELFKAVLHNP----------------------------------------------------------HLKLLSLYGT-SLSQSDIRHLCETLKHPMCKIEELILGKCDISSEVCEDIASVLACN-SKLKHLSLVENPLRDEGMTLLCEALKHSHCALERLMLMYCCLTSVSCDSISEVLLCS-KSLSLLDLGSNALEDNGVASLCAALKHPGCSIRELWLMGCFLTSDSCKDIAAVLICN-GKLKTLKLGHNEIGDTGVRQLCAALQHPHCKLECLGLQTCPITRACCDDIAAALIA-CKTLRSLNLDWIALDADAVVVLCEALSHPDCALQMLGLHK-SGFDEETQKILMSVEEKIPHLTISHGPWIDEEYKIRGVLL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86W25-1", "uniprot_id": "NAL13_HUMAN", "id": "Q86W25-1", "name": "NACHT, LRR and PYD domains-containing protein 13", "aln": "----------------------------------------------------------------------MNFSVITCPNGGTNQGLLPYLMALDQYQLEEFKLCLEPQQLMDFWSAPQGHFPRIPWANLRAADPLNLSFLLDEHFPKGQAWKVVLGIFQTMNLTSLCEKVRAEMKENVQTQELQDPTQEDLEMLEAAAGNMQTQGCQDPNQEELDELEEETGNVQAQGCQDPNQEEPEMLEEADHRRKYRENMKAELLETWDNISWPKDHVYIRN-TSKDEH-------------------------------EELQRLLDP-NRTRAQAQTIVLVGRAGVGKTTLAMQAMLHWANGVLFQQRFSYVFYLSCHKIR-YMKETTFAELISLDWPDFDAPIEEFMSQPEKLLFIIDGFEEIIISESRSESLDDGSPCTDWYQELPVTKILHSLLKKELVPLATLLITIKTWFVRDLKASLVNPCFVQITGFTGDDLRVYFMRHFDDSSEVEKILQQLRKNETLFHSCSAPMVCWTVCSCLKQPKVRYYDLQSITQTTTSLYAYFFSNLFSTAEVDLADDSWPGQWRALCSLAIEGLWSMNFTFNKEDTEIEGLEVPFIDSLYEFNILQKINDC----GGCTTFTHLSFQEFFAAMSFVLEEP--------REFPPHSTKPQEMKMLLQHVLLDKEAYWTPVVLFFFGLLNKNIARELEDTLHCKISPRVMEELLKWGEELGKAESASLQFHILRLFHCLHESQEEDFTKKMLGRIFEVDLN-ILEDEELQASSFCLKHCKRLNKLRLSVSSHILER------DLEILETS----------KFDSRMHAWNSICSTLVTNENLHELDLSNSKLHASSVKGLCLALKNPRCKVQKLTCKSVTPE-WVLQDLIIALQGNS---------------------------------------------------------KLTHLNFSSN-KLG-MTVPLILKALRHSACNLKYLCLEKCNLSAASCQDLALFLTSI-QHVTRLCLGFNRLQDDGIKLLCAALTHPKCALERLELWFCQLAAPACKHLSDALLQN-RSLTHLNLSKNSLRDEGVKFLCEALGRPDGNLQSLNLSGCSFTREGCGELANALSHN-HNVKILDLGENDLQDDGVKLLCEALK-PHRALHTLGLAKCNLTTACCQHLFSVLSS-SKSLVNLNLLGNELDTDGVKMLCKALKKSTCRLQKLG----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86W28-1", "uniprot_id": "NALP8_HUMAN", "id": "Q86W28-1", "name": "NACHT, LRR and PYD domains-containing protein 8", "aln": "----------------------------------------------MSDVNPPSDTPIPFSSSSTHSSHIPPWTFSCYPGSPCENGVMLYMRNVSHEELQRFKQLLLT--------ELSTGTMPITWDQVETASWAEVVHLLIERFPGRRAWDVTSNIFAIMNCDKMCVVVRREINAILPTLEPEDLNVG-------------------------------------------ETQVNLEEGESGKIRRYKSNVMEKFFPIWDITTWPGNQRDFFYQGVHRHE-------------------------------EYLPCLLLPKRPQGRQPKTVAIQGAPGIGKTILAKKVMFEWARNKFYAHKRWCAFYFHCQEVN-QTTDQSFSELIEQKWPGSQDLVSKIMSKPDQLLLLLDGFEELTSTLIDRLED----LSEDWRQKLPGSVLLSSLLSKTMLPEATLLIMIRFTSWQTCKPLLKCPSLVTLPGFNTMEKIKYFQMYFGHTEEGDQVLSFAMENTILFSMCRVPVVCWMVCSGLKQQMERGNNLTQSCPNATSVFVRYISSLFPTRAENFSRKIHQAQLEGLCHLAADSMWHRKWVLGKEDLEEAKLDQTGVTAFLGMSILRRIAGE----EDHYVFTLVTFQEFFAALFYVLCFPQR------LKNFHVLSHVNIQRLIAS--PRGSKSYLSHMGLFLFGFLNEACASAVEQSFQCKVSFGNKRKLLKVIPLLHKCDPPSPGSGVPQLFYCLHEIREEAFVSQALNDYHKVVLR-IGNNKEVQVSAFCLKRCQYLHEVELTVTLNFMNVWKLSSSSHPGSEAP----------ESNGLHRWWQDLCSVFATNDKLEVLTMTNSVLGPPFLKALAAALRHPQCKLQKLLLRRVNST-MLNQDLIGVLTGN---------------------------------------------------------QHLRYLEIQHV-EVESKAVKLLCRVLRSPRCRLQCLRLEDCLATPRIWTDLGNNLQGN-GHLKTLILRKNSLENCGAYYLS------VAQLERLSIENCNLTQLTCESLASCLRQS-KMLTHLSLAENALKDEGAKHIWNALPHLRCPLQRLVLRKCDLTFNCCQDMISALCKN-KTLKSLDLSFNSLKDDGVILLCEALKNPDCTLQILELENCLFTSICCQAMASMLRK-NQHLRHLDLSKNAIGVYGILTLCEAFSSQKKREEVIFCIP-----AWTRITSFSPTPHPPDFTGKSDCLSQINP---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8WX94-1", "uniprot_id": "NALP7_HUMAN", "id": "Q8WX94-1", "name": "NACHT, LRR and PYD domains-containing protein 7", "aln": "-----------------------------------------------------------------------------MTSPQLEWTLQTLLEQLNEDELKSFKSLLWA-------FPLEDVLQKTPWSEVEEADGKKLAEILVNTSSENWIRNATVNILEEMNLTELCKMAKAEMMEDGQ---------------------------------------------------VQEIDNPELGDAEEDSELAKPGEKEGWRNSMEKQSLVWKNTFWQG---DIDN----------------FHDD------VTLRNQRFIPFLNPRTPRKLTPYTVVLHGPAGVGKTTLAKKCMLDWTDCNLSPT-LRYAFYLSCKELS-RMGPCSFAELISKDWPELQDDIPSILAQAQRILFVVDGLDELKVPPGALIQD----ICGDWEKKKPVPVLLGSLLKRKMLPRAALLVTTRPRALRDLQLLAQQPIYVRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPTCLTRTGLFLRFLCSRFPQG------AQLRGALRTLSLLAAQGLWAQMSVFHREDLERLGVQESDLRLFLDGDILRQDRVS----KGCYSFIHLSFQQFLTALFYALEKEEG------EDRDGHAWDIGDVQKLLSGEERLKNPDLIQVGHFLFGLANEKRAKELEATFGCRMSPDIKQELLQCKAHLHAN-KPLSVTDLKEVLGCLYESQEEELAKVVVAPFKEISIH-LTNTSEVMHCSFSLKHCQDLQKLSLQVAKGVFLENYMDFELDIEFERCTYLTIPNWARQDLRSLRLWTDFCSLFSSNSNLKFLEVKQSFLSDSSVRILCDHVTRSTCHLQKVEIKNVTPD-TAYRDFCLAFIGKK---------------------------------------------------------TLTHLTLAGHIEWERTMMLMLCDLLRNHKCNLQYLRLGGHCATPEQWAEFFYVLKAN-QSLKHLRLSANVLLDEGAMLLYKTMTRPKHFLQMLSLENCRLTEASCKDLAAVLVVS-KKLTHLCLAKNPIGDTGVKFLCEGLSYPDCKLQTLVLQQCSITKLGCRYLSEALQEA-CSLTNLDLSINQI-ARGLWILCQALENPNCN----------------------------------------------------------LKHLRLKT-YETNLEIKKLLEEVKEKNPKLTIDCNASG--ATAPPCCDFFC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NX02-1", "uniprot_id": "NALP2_HUMAN", "id": "Q9NX02-1", "name": "NACHT, LRR and PYD domains-containing protein 2", "aln": "----------------------------------------------------------------------------MVSSAQMGFNLQALLEQLSQDELSKFKYLITT-------FSLAHELQKIPHKEVDKADGKQLVEILTTHCDSYWVEMASLQVFEKMHRMDLSERAKDEVREAALKSFNKRKPL------------------------------------------SLGITRKERPPLDVDEMLERFKTEAQAFTETKGNVICLGKEVFKGKKPDKDNRCRYILKTKFREMWKSWPGDSKEVQVMAERYKMLIPFSNPRVLPGPFSYTVVLYGPAGLGKTTLAQKLMLDWAEDNLIHK-FKYAFYLSCRELS-RLGPCSFAELVFRDWPELQDDIPHILAQARKILFVIDGFDELGAAPGALIED----ICGDWEKKKPVPVLLGSLLNRVMLPKAALLVTTRPRALRDLRILAEEPIYIRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPTCLTRTGLFLRFLCSRFPQG------AQLRGALRTLSLLAAQGLWAQTSVLHREDLERLGVQESDLRLFLDGDILRQDRVS----KGCYSFIHLSFQQFLTALFYTLEKEEE------EDRDGHTWDIGDVQKLLSGVERLRNPDLIQAGYYSFGLANEKRAKELEATFGCRMSPDIKQELLRCDISCKG--GHSTVTDLQELLGCLYESQEEELVKEVMAQFKEISLH-LN-AVDVVPSSFCVKHCRNLQKMSLQVIKENLPENVTASESDAEVERS---------QDDQHMLPFWTDLCSIFGSNKDLMGLAINDSFLSASLVRILCEQIASDTCHLQRVVFKNISPA-DAHRNLCLALRGHK---------------------------------------------------------TVTYLTLQGNDQDD--MFPALCEVLRHPECNLRYLGLVSCSATTQQWADLSLALEVN-QSLTCVNLSDNELLDEGAKLLYTTLRHPKCFLQRLSLENCHLTEANCKDLAAVLVVS-RELTHLCLAKNPIGNTGVKFLCEGLRYPECKLQTLVLWNCDITSDGCCDLTKLLQEK-SSLLCLDLGLNHIGVKGMKFLCEALRKPLCNLRCLWLWGCSIPPFSCEDLCSALSC-NQSLVTLDLGQNPLGSSGVKMLFETLTCSSGTLRTLRLKI-DDFNDELNKLLEEIEEKNPQLIIDTEKHHPWAERPSSHDFMI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JW23-1", "uniprot_id": "A0A0G2JW23_RAT", "id": "A0A0G2JW23-1", "name": "NACHT, LRR and PYD domains-containing protein 12", "aln": "--------------------------------------------------------------------------MLPATAKDALHRLSTYLEELEAGELKKFKLYLG--------IAEELGQDKIPRGRMEMAGPLEMAQLMVAHMGTKEAWLLALSTFERIHRKDLWERGQGED--------------------------------LVRVTPSNGLC---SLESQST----CLSDVSPDAPRKDPQITYKDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPIWAQQKLLETGWEHSRTRGHQASPIQMETLFEPDEERPEPPRTVVLQGAAGMGKSMLTHKVMLDWADGRLFQDQFDYVFYISCRELNRSHTQCSVHDLLSSCWPEHGAPLEDLIRAPDRLLFIIDGFHELHPSFHDVQGP----WCHCWEEKRPTELLLGSLIRRLLLPQLSLLITTRPCALEKLHGLLEHPRHVEILGFSEAEREEYFYRYFHNTGQASQVFSFMRDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTSRTTTAVYMFYLLSLMQPKPGTPTFKVPAN-QRGLVSLAAEGLWNQKILFEEEDLGKHGLDGAEVSTFLNVNIFQKGIKC----EKFYSFIHLSFQEFFTAMYCALHGRE------------------AVRRALAEYGFSERNFLAHTVRFLFGLLNEEMRCYLERNLGWTISPQVKEEALAWIQNKARSEGSTLQHGSLELLSCLYEIQEEDFIQQALSHFQVVVVRNLSTKMEHVVCSFCARYCRGTEVLHLYGSAYSTGAED-----GPPEPPGAQTQSTHSQERNILPDIYSAYLSATICTNSNLIELALYRNALGSQGVRLLCQGLRHANCKLQNLRLKRCHISGSACQDLAAAIIAN---------------------------------------------------------RNLIRLDLSGN-SIGVLGLELLCEGLQHPMCRLQMIQLRKCLLEAAAGRALASVLSNN-SHLVELDLTGNPLEDLGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMN-QSLMELDLGLNDLGDSGALLLCEGLRHPDCKLQTLRLGICRLGSDACAGVASVLQVN-TCLRELDLSFNDLGDRGLWLLGEGLRHQTCRLQKLWLDSCGLTSKACEDLSSVLGI-SQTLNELYLTNNALGDTGVRLLCKRLRHPGCKLRVLWLFG-MDLNKVTHRRMAALRVTKPYLDIGC-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q5R7-1", "uniprot_id": "NAL12_MOUSE", "id": "E9Q5R7-1", "name": "NACHT, LRR and PYD domains-containing protein 12", "aln": "--------------------------------------------------------------------------MLPSTARDGLYRLSTYLEELEAGELKKFKLFLG--------IAEDLSQDKIPWGRMEKAGPLEMAQLMVAHMGTREAWLLALSTFQRIHRKDLWERGQGED--------------------------------LVRVTPNNGLC---LFESQSA----CPLDVSPNAPRKDLQTTYKDYVRRKFQLMEDRNARLGECVNLSNRYTRLLLVKEHSNPIWTQQKFVDVEWERSRTRRHQTSPIQMETLFEPDEERPEPPHTVVLQGAAGMGKSMLAHKVMLDWADGRLFQGRFDYVFYISCRELNRSHTQCSVQDLISSCWPERGISLEDLMQAPDRLLFIIDGFDKLHPSFHDAQGP----WCLCWEEKQPTEVLLGSLIRRLLLPQVSLLITTRPCALEKLHGLLEHPRHVEILGFSEEARKEYFYRYFHNTGQASRVLSFLMDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTPRTTTAVYMFYLLSLMQPKPGTPTFKVPAN-QRGLVSLAAEGLWNQKILFDEQDLGKHGLDGADVSTFLNVNIFQKGIKC----EKFYSFIHLSFQEFFAAMYCALNGRE------------------AVRRALAEYGFSERNFLALTVHFLFGLLNEEMRCYLERNLGWSISPQVKEEVLAWIQNKAGSEGSTLQHGSLELLSCLYEVQEEDFIQQALSHFQVVVVRSISTKMEHMVCSFCARYCRSTEVLHLHGSAYSTGMED-----DPPEPSGVQTQSTYLQERNMLPDVYSAYLSAAVCTNSNLIELALYRNALGSQGVRLLCQGLRHASCKLQNLRLKRCQISGSACQDLAAAVIAN---------------------------------------------------------RNLIRLDLSDN-SIGVPGLELLCEGLQHPRCRLQMIQLRKCLLEAAAGRSLASVLSNN-SYLVELDLTGNPLEDSGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMN-QSLLELDLGLNDLGDSGVLLLCEGLSHPDCKLQTLRLGICRLGSVACVGIASVLQVN-TCLQELDLSFNDLGDRGLQLLGEGLRHQTCRLQKLWLDNCGLTSKACEDLSSILGI-SQTLHELYLTNNALGDTGVCLLCKRLRHPGCKLRVLWLFG-MDLNKKTHRRMAALRVTKPYLDIGC-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P59046-1", "uniprot_id": "NAL12_HUMAN", "id": "P59046-1", "name": "NACHT, LRR and PYD domains-containing protein 12", "aln": "--------------------------------------------------------------------------MLRTAGRDGLCRLSTYLEELEAVELKKFKLYLG--------TATELGEGKIPWGSMEKAGPLEMAQLLITHFGPEEAWRLALSTFERINRKDLWERGQRED--------------------------------LVRDTPPGGPS---SLGNQST----CLLEVSLVTPRKDPQETYRDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPMQVQQQLLDTGRGHARTVGHQASPIKIETLFEPDEERPEPPRTVVMQGAAGIGKSMLAHKVMLDWADGKLFQGRFDYLFYINCREMNQSATECSMQDLIFSCWPEPSAPLQELIRVPERLLFIIDGFDELKPSFHDPQGP----WCLCWEEKRPTELLLNSLIRKKLLPELSLLITTRPTALEKLHRLLEHPRHVEILGFSEAERKEYFYKYFHNAEQAGQVFNYVRDNEPLFTMCFVPLVCWVVCTCLQQQLEGGGLLRQTSRTTTAVYMLYLLSLMQPKPGAPRLQPPPN-QRGLCSLAADGLWNQKILFEEQDLRKHGLDGEDVSAFLNMNIFQKDINC----ERYYSFIHLSFQEFFAAMYYILDEGEG-----------GAGPDQDVTRLLTEYAFSERSFLALTSRFLFGLLNEETRSHLEKSLCWKVSPHIKMDLLQWIQSKAQSDGSTLQQGSLEFFSCLYEIQEEEFIQQALSHFQVIVVSNIASKMEHMVSSFCLKRCRSAQVLHLYGATYSADGED-----RARCSAGAHTLLVQLPERTVLLDAYSEHLAAALCTNPNLIELSLYRNALGSRGVKLLCQGLRHPNCKLQNLRLKRCRISSSACEDLSAALIAN---------------------------------------------------------KNLTRMDLSGN-GVGFPGMMLLCEGLRHPQCRLQMIQLRKCQLESGACQEMASVLGTN-PHLVELDLTGNALEDLGLRLLCQGLRHPVCRLRTLWLKICRLTAAACDELASTLSVN-QSLRELDLSLNELGDLGVLLLCEGLRHPTCKLQTLRLGICRLGSAACEGLSVVLQAN-HNLRELDLSFNDLGDWGLWLLAEGLQHPACRLQKLWLDSCGLTAKACENLYFTLGI-NQTLTDLYLTNNALGDTGVRLLCKRLSHPGCKLRVLWLFG-MDLNKMTHSRLAALRVTKPYLDIGC-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A523-1", "uniprot_id": "NLRP3_RAT", "id": "D4A523-1", "name": "NACHT, LRR and PYD domains-containing protein 3", "aln": "--------------------------------------------------------------------------MKMMSVR---CKLAQYLEDLEDVDLKKFKMHLED-------YPPEKGCVPIPRGQMEKADHLDLATLMIDFNGEEKAWGMAVWIFAAINRRDLWEKAKKDQPEWN----------------------------DACTSNLSMVCQEDSLEEEWIGLLGYLSRISICKKKKDYCKIYRRHVRSRFYSIKDRNARLGESVDLNRRYTQLQLVKEHPSKQEREHELLTIGR--TKMWDRPMSSLKLELLFEPEDEHLEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVS-LRAPKSLADLIISCWPDPNPPVCKILCKPSRILFLMDGFDELQGAFDEHIEE----VCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEILFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGIEEHLFSAY-LPGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDC----ERFYSFSHMTFQEFFAAMYYLLEEEEEGVTVRKGPEGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQRQPSQLELFYCLYEMQEEDFVQSAMGHFPKIEIN-LSTRMDHVVSSFCIKNCHRVKTLSLGFLHNSPKEEE-----EEK------------------------------------------RGSQPLDQVQCVFP-DPHVACSSR---LVNCCLTSSFCRGLFSSLSTN---------------------------------------------------------QSLTELDLSDN-TLGDPGMRVLCEALQHPGCNIQRLWLGRCGLTHQCCFNISSVLSSS-QKLVELDLSDNALGDFGVRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSN-HSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSLCCSALTSVLKTN-QNLTHLYLRSNALGDMGLKLLCEGLLHPDCKLQMLELDNCSLTSHSCWDLSTILTH-NQSLRKLNLSNNDLGDLCVVTLCEVLKQQGCLLQSLQLGE-MYLNCETKRTLEALQEEKPELTVVFEISW-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4B8-1", "uniprot_id": "NLRP3_MOUSE", "id": "Q8R4B8-1", "name": "NACHT, LRR and PYD domains-containing protein 3", "aln": "----------------------------------------------------------------------------MTSVR---CKLAQYLEDLEDVDLKKFKMHLED-------YPPEKGCIPVPRGQMEKADHLDLATLMIDFNGEEKAWAMAVWIFAAINRRDLWEKAKKDQPEWN----------------------------DTCTSHSSMVCQEDSLEEEWMGLLGYLSRISICKKKKDYCKMYRRHVRSRFYSIKDRNARLGESVDLNSRYTQLQLVKEHPSKQEREHELLTIGR--TKMRDSPMSSLKLELLFEPEDGHSEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVS-LRTPRSLADLIVSCWPDPNPPVCKILRKPSRILFLMDGFDELQGAFDEHIGE----VCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEVLFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGIEEHLFSDY-LQGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDC----ERFYSFSHMTFQEFFAAMYYLLEEEAEGETVRKGPGGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQWQPSQLELFYCLYEMQEEDFVQSAMDHFPKIEIN-LSTRMDHVVSSFCIKNCHRVKTLSLGFFHNSPKEEE-----EER------------------------------------------RGGRPLDQVQCVFP-DTHVACSSR---LVNCCLTSSFCRGLFSSLSTN---------------------------------------------------------RSLTELDLSDN-TLGDPGMRVLCEALQHPGCNIQRLWLGRCGLSHQCCFDISSVLSSS-QKLVELDLSDNALGDFGIRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSN-HSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSICCSALTSVLKTN-QNFTHLYLRSNALGDTGLRLLCEGLLHPDCKLQMLELDNCSLTSHSCWNLSTILTH-NHSLRKLNLGNNDLGDLCVVTLCEVLKQQGCLLQSLQLGE-MYLNRETKRALEALQEEKPELTIVFEISW-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96P20-1", "uniprot_id": "NLRP3_HUMAN", "id": "Q96P20-1", "name": "NACHT, LRR and PYD domains-containing protein 3", "aln": "--------------------------------------------------------------------------MKMASTR---CKLARYLEDLEDVDLKKFKMHLED-------YPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSD--------------------------NARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQQEREQELLAIGK--TKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVS-LVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGP----LCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAH-LWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDC----EKFYSFIHMTFQEFFAAMYYLLEEEKEGRTN--VPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEIN-LSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEE-----EEE------------------------------------------KEGRHLDMVQCVLPSSSHAACSHG---LVNSHLTSSFCRGLFSVLSTS---------------------------------------------------------QSLTELDLSDN-SLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSN-QKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTS-HSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTN-QNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTS-SQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSE-MYFNYETKSALETLQEEKPELTVVFEPSW-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z7N0-1", "uniprot_id": "A1Z7N0_DROME", "id": "A1Z7N0-1", "name": "Leucine-rich repeat-containing protein 34", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCDVLLPCEYNPKECPSPAAEKSRLFTILLLYCWQREYDKRPYRQFQFKRLTFEERIGRRYHCIRDLRIIVNYLLR-----------RPQLSVQISSLVVSNWDAGLLKDFVRSLLPVWYIELRLMRFPREFFVMLRLNAAKMN-----VSQLSLEGTPLTDEDVRILREFLLVSKTLRR----LNVSSCS--------------------------------------------------------LTQFNFALIADGVYK----------SPGVRR------------------LSANRLLGMSLSLDTEKISSVLSSLLMQNTLW-----------ALSLEHC------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELTAQDMIPIAEHLARTNSKFRRLRIACNKIGPDGAFFLLRGMSMG-GNLELLDLS-----------------------------YCSIGTHGGEWVAKYLASC-RRLQVLHLNYNDMGPTAVNLILLAMKK-QCKLEKLTLYGNHFDSRTAMIVRRLLDAE-VVLHSELDISYTYDEALQDYRVVPWR------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M6YSM0-1", "uniprot_id": "A0A8M6YSM0_DANRE", "id": "A0A8M6YSM0-1", "name": "", "aln": "MSHKQTLKYFSPVCSSVQQERSDSAEPSSVSVKSHWSIDPPPQMTERRDSLSLALQERSDSPEPSHVSMKSDWSIDPPPQMKEENRSLVQQERSPKSSCVSMKRDWSIDPPPQMNDEDGQKRLSLVQQERSDSAEPSLVSMKSDWSIDPPPQMKDGDRQKSLSLVQQERSDSPEPSHVTMKSNWSIDPPPQ------MTDRRDSLRQIPRPRPGAEEPISKKMKYDESVIKSQECMENPSLIFSHEVNTFRVNLLKKFQCLYEGMVTQDNPALLNEIYTELYITESESGEISNEHEVRQIETQ-SRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQD-VQLIFPLPFREIN-LMKDKTLSLSDLLQLFFPETKEIDIFSDKYKILFIFDGLDECRLLLNFKSNE----ILQHVTKTSSVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHR-VTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIP-KTLTQMYTHFLMAQINTKDMKYTGKKDKDMIFKLGKLAYEQLERGNVIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFIHLSVQEHLAALYVHLLFTN------------------HNRNVFEQMTKKTSKTLDILDCFHSNSPENVLLSELHQKAVDEALQSKNGHLDLFLRFLLGLSLESNQILLQELMIKFRSSSDSSEKTVEYIKKRINNICLPEKSINLFYCLNELGDHSLVKEIQQYMDYG-----------------------------------------------------TLAETKISCGQWSALVFILLTVEQAMDVFELN-------------------------------------------------------------------------------KFIGLKKS---SDEVLRKLLPVIKKS----RSAIMDDCNITAEGCAYLASALGSNPSYLRELDLSANKLQDSGIKKLSKGLQDSHCKLEKLNLYHCGVTNEGCAALASALKSNPEHLRDLNLSENKIGNLGLTCLSEILKNSLCKLEILRLCQCGIT--DCTDLASALISNPEHLRELELSLNKIGDSGVTALCAAFEDPRFKLEKLGLSGCGLTDEGCAALTSALRSNHEHLRDLDLSGNKVDKEVKGSILQRILEKLNNIQILSV---------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : : . : : .. : : : . . : : . .: . . . : : . : : : : : : * . :: : . : * : * : . : : * : : . : : . ", "identical_positions": 4, "similar_positions": 49, "identity": "0.31%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-148", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04911-1", "uniprot_id": "H2A1_YEAST", "id": "P04911-1", "name": "Histone H2A.1", "aln": "--------MSGGKGGKAGSAAKASQSRSAKAGLTFPVG---------------------------------------------RVHRLLRRGNYAQRIGSGAP------------VYLTAVLEYLAAEILELAGNAARDNKKT-RIIPRHLQLAIRNDDELNKLLGNVTIAQG-----GVLPNIHQNLLPKKSAKATKASQEL-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P04912-1", "uniprot_id": "H2A2_YEAST", "id": "P04912-1", "name": "Histone H2A.2", "aln": "--------MSGGKGGKAGSAAKASQSRSAKAGLTFPVG---------------------------------------------RVHRLLRRGNYAQRIGSGAP------------VYLTAVLEYLAAEILELAGNAARDNKKT-RIIPRHLQLAIRNDDELNKLLGNVTIAQG-----GVLPNIHQNLLPKKSAKTAKASQEL-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q7L7L0-1", "uniprot_id": "H2A3_HUMAN", "id": "Q7L7L0-1", "name": "Histone H2A type 3", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG---------------------------------------------RVHRLLRKGNYSERVGAGAP------------VYLAAVLEYLTAEILELAGNAARDNKKT-RIIPRHLQLAIRNDEELNKLLGRVTIAQG-----GVLPNIQAVLLPKKTESHHKAKGK------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4FZT6-1", "uniprot_id": "H2A3_RAT", "id": "Q4FZT6-1", "name": "Histone H2A type 3", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG---------------------------------------------RVHRLLRKGNYSERVGAGAP------------VYLAAVLEYLTAEILELAGNAARDNKKT-RIIPRHLQLAIRNDEELNKLLGRVTIAQG-----GVLPNIQAVLLPKKTESHHKAKGK------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFU2-1", "uniprot_id": "H2A3_MOUSE", "id": "Q8BFU2-1", "name": "Histone H2A type 3", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG---------------------------------------------RVHRLLRKGNYSERVGAGAP------------VYLAAVLEYLTAEILELAGNAARDNKKT-RIIPRHLQLAIRNDEELNKLLGRVTIAQG-----GVLPNIQAVLLPKKTESHHKAKGK------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZVK7-1", "uniprot_id": "D3ZVK7_RAT", "id": "D3ZVK7-1", "name": "Histone H2A", "aln": "--------MTG-RGKQGGKARAKAKTRSSRAGLQFPVG---------------------------------------------RVHRLLRKGNYSERVGAGAP------------VYLAAVLEYLTAEILELAGNAARDNKKT-RIIPRHLQLAIRNDEELNKLLGRVTIAQG-----GVLPNIQAVLLPKKTESHHKAKGK------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6ARS7-1", "uniprot_id": "A0A8I6ARS7_RAT", "id": "A0A8I6ARS7-1", "name": "Histone H2A", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG---------------------------------------------RVHRLLRKGSYSERVGAGAP------------VYLAAVMEYLTAEILELAGNAARDNKKT-RIIPRHLQLAIRNDEELNKLLGRVTIAQG-----GVLPNIQAVLLPKKTESYHKAKGK------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0RDM4-1", "uniprot_id": "M0RDM4_RAT", "id": "M0RDM4-1", "name": "Histone H2A", "aln": "--------MSG-RGKQGSKARAKAKTRSFRAGLQFPVG---------------------------------------------RVHRLLRKGNYSERVGAGAP------------VYLAAVLEYLTAEILELAGNAARDNKKT-RIIPRHLQLAIRNDEELNKLLGRVTIAQG-----GVLPNIQAVLLPKKTESHHKVK--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q93077-1", "uniprot_id": "H2A1C_HUMAN", "id": "Q93077-1", "name": "Histone H2A type 1-C", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG---------------------------------------------RVHRLLRKGNYAERVGAGAP------------VYLAAVLEYLTAEILELAGNAARDNKKT-RIIPRHLQLAIRNDEELNKLLGRVTIAQG-----GVLPNIQAVLLPKKTESHHKAKGK------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0C170-1", "uniprot_id": "H2A1E_RAT", "id": "P0C170-1", "name": "Histone H2A type 1-E", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG---------------------------------------------RVHRLLRKGNYAERVGAGAP------------VYLAAVLEYLTAEILELAGNAARDNKKT-RIIPRHLQLAIRNDEELNKLLGRVTIAQG-----GVLPNIQAVLLPKKTESHHKAKGK------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C0S8-1", "uniprot_id": "H2A1_HUMAN", "id": "P0C0S8-1", "name": "Histone H2A type 1", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG---------------------------------------------RVHRLLRKGNYAERVGAGAP------------VYLAAVLEYLTAEILELAGNAARDNKKT-RIIPRHLQLAIRNDEELNKLLGKVTIAQG-----GVLPNIQAVLLPKKTESHHKAKGK------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6GSS7-1", "uniprot_id": "H2A2A_MOUSE", "id": "Q6GSS7-1", "name": "Histone H2A type 2-A", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG---------------------------------------------RVHRLLRKGNYAERVGAGAP------------VYMAAVLEYLTAEILELAGNAARDNKKT-RIIPRHLQLAIRNDEELNKLLGKVTIAQG-----GVLPNIQAVLLPKKTESHHKAKGK------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6FI13-1", "uniprot_id": "H2A2A_HUMAN", "id": "Q6FI13-1", "name": "Histone H2A type 2-A", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG---------------------------------------------RVHRLLRKGNYAERVGAGAP------------VYMAAVLEYLTAEILELAGNAARDNKKT-RIIPRHLQLAIRNDEELNKLLGKVTIAQG-----GVLPNIQAVLLPKKTESHHKAKGK------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CC09-1", "uniprot_id": "H2A2A_RAT", "id": "P0CC09-1", "name": "Histone H2A type 2-A", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG---------------------------------------------RVHRLLRKGNYAERVGAGAP------------VYMAAVLEYLTAEILELAGNAARDNKKT-RIIPRHLQLAIRNDEELNKLLGKVTIAQG-----GVLPNIQAVLLPKKTESHHKAKGK------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A9UMV8-1", "uniprot_id": "H2AJ_RAT", "id": "A9UMV8-1", "name": "Histone H2A.J", "aln": "--------MSG-RGKQGGKVRAKAKSRSSRAGLQFPVG---------------------------------------------RVHRLLRKGNYAERVGAGAP------------VYLAAVLEYLTAEILELAGNAARDNKKT-RIIPRHLQLAIRNDEELNKLLGRVTIAQG-----GVLPNIQAVLLPKKTES-QKVKSK------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64523-1", "uniprot_id": "H2A2C_MOUSE", "id": "Q64523-1", "name": "Histone H2A type 2-C", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG---------------------------------------------RVHRLLRKGNYAERVGAGAP------------VYMAAVLEYLTAEILELAGNAARDNKKT-RIIPRHLQLAIRNDEELNKLLGKVTIAQG-----GVLPNIQAVLLPKKTES-HKAKSK------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IUE6-1", "uniprot_id": "H2A2B_HUMAN", "id": "Q8IUE6-1", "name": "Histone H2A type 2-B", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG---------------------------------------------RVHRLLRKGNYAERVGAGAP------------VYLAAVLEYLTAEILELAGNAARDNKKT-RIIPRHLQLAVRNDEELNKLLGGVTIAQG-----GVLPNIQAVLLPKKTESHKPGKNK------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64522-1", "uniprot_id": "H2A2B_MOUSE", "id": "Q64522-1", "name": "Histone H2A type 2-B", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG---------------------------------------------RVHRLLRKGNYAERVGAGAP------------VYMAAVLEYLTAEILELAGNAARDNKKT-RIIPRHLQLAVRNDEELNKLLGGVTIAQG-----GVLPNIQAVLLPKKTESHKPGKNK------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58IZ20-1", "uniprot_id": "A0AC58IZ20_DANRE", "id": "A0AC58IZ20-1", "name": "Histone H2A", "aln": "--------MSG-RGKTGGKARAKAKSRSSRAGLQFPVG---------------------------------------------RVHRLLRKGNYAQRVGAGAP------------VYLAAVLEYLTAEILELAGNAARDNKKT-RIIPRHLQLAVRNDEELNKLLGGVTIAQG-----GVLPNIQAVLLPKKTEKAAKGK--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P84051-1", "uniprot_id": "H2A_DROME", "id": "P84051-1", "name": "Histone H2A", "aln": "--------MSG-RGK-GGKVKGKAKSRSNRAGLQFPVG---------------------------------------------RIHRLLRKGNYAERVGAGAP------------VYLAAVMEYLAAEVLELAGNAARDNKKT-RIIPRHLQLAIRNDEELNKLLSGVTIAQG-----GVLPNIQAVLLPKKTEKKA-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4AB57-1", "uniprot_id": "Q4AB57_DROME", "id": "Q4AB57-1", "name": "Histone H2A", "aln": "--------MSG-RGK-GGKVKGKAKSRSDRAGLQFPVG---------------------------------------------RIHRLLRKGNYAERVGAGAP------------VYLAAVMEYLAAEVLELAGNAARDNKKT-RIIPRHLQLAIRNDEELNKLLSGVTIAQG-----GVLPNIQAVLLPKKTEKKA-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M0R7B4-1", "uniprot_id": "M0R7B4_RAT", "id": "M0R7B4-1", "name": "", "aln": "MSETAPAAPAAPAPVEKTPVKKKAKKTSSAAGKRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGILVQTKGTGASGSFKLNKKASSGEAKPKAKKVGAAKAKKPAGSAKKPKKATGSATPRKTKKTPKKAKKPGATAGAKKVSKSPKKVKAAKPKKAAKSPAKAKAPKAKATKPKASKPKANKAKKAAPRKK", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . ::. * ** . * :: *: :* : *:**. . . : :*: : **.* : :* * **: : : :: .: . . .:::. .. *: .* . ", "identical_positions": 19, "similar_positions": 42, "identity": "8.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-152", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04911-1", "uniprot_id": "H2A1_YEAST", "id": "P04911-1", "name": "Histone H2A.1", "aln": "--------MSGGKGGKAGSAAKASQSRSAKAGLTFPVG-RVHRLLRRGNYAQRIGSGAPVYLTAVLEYLAAEILELAGNAARDNKKTR-IIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIHQNLLPKKSAKAT---------------------KASQEL---------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P04912-1", "uniprot_id": "H2A2_YEAST", "id": "P04912-1", "name": "Histone H2A.2", "aln": "--------MSGGKGGKAGSAAKASQSRSAKAGLTFPVG-RVHRLLRRGNYAQRIGSGAPVYLTAVLEYLAAEILELAGNAARDNKKTR-IIPRHLQLAIRNDDELNKLLGNVTIAQGGVLPNIHQNLLPKKSAKTA---------------------KASQEL---------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q7L7L0-1", "uniprot_id": "H2A3_HUMAN", "id": "Q7L7L0-1", "name": "Histone H2A type 3", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHH---------------------KAKGK----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4FZT6-1", "uniprot_id": "H2A3_RAT", "id": "Q4FZT6-1", "name": "Histone H2A type 3", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHH---------------------KAKGK----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BFU2-1", "uniprot_id": "H2A3_MOUSE", "id": "Q8BFU2-1", "name": "Histone H2A type 3", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHH---------------------KAKGK----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZVK7-1", "uniprot_id": "D3ZVK7_RAT", "id": "D3ZVK7-1", "name": "Histone H2A", "aln": "--------MTG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHH---------------------KAKGK----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6ARS7-1", "uniprot_id": "A0A8I6ARS7_RAT", "id": "A0A8I6ARS7-1", "name": "Histone H2A", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGSYSERVGAGAPVYLAAVMEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESYH---------------------KAKGK----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0RDM4-1", "uniprot_id": "M0RDM4_RAT", "id": "M0RDM4-1", "name": "Histone H2A", "aln": "--------MSG-RGKQGSKARAKAKTRSFRAGLQFPVG-RVHRLLRKGNYSERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHH---------------------KVK------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q93077-1", "uniprot_id": "H2A1C_HUMAN", "id": "Q93077-1", "name": "Histone H2A type 1-C", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHH---------------------KAKGK----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0C170-1", "uniprot_id": "H2A1E_RAT", "id": "P0C170-1", "name": "Histone H2A type 1-E", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESHH---------------------KAKGK----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P0C0S8-1", "uniprot_id": "H2A1_HUMAN", "id": "P0C0S8-1", "name": "Histone H2A type 1", "aln": "--------MSG-RGKQGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHH---------------------KAKGK----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6GSS7-1", "uniprot_id": "H2A2A_MOUSE", "id": "Q6GSS7-1", "name": "Histone H2A type 2-A", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHH---------------------KAKGK----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6FI13-1", "uniprot_id": "H2A2A_HUMAN", "id": "Q6FI13-1", "name": "Histone H2A type 2-A", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHH---------------------KAKGK----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CC09-1", "uniprot_id": "H2A2A_RAT", "id": "P0CC09-1", "name": "Histone H2A type 2-A", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHH---------------------KAKGK----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IUE6-1", "uniprot_id": "H2A2B_HUMAN", "id": "Q8IUE6-1", "name": "Histone H2A type 2-B", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTESHK---------------------PGKNK----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64522-1", "uniprot_id": "H2A2B_MOUSE", "id": "Q64522-1", "name": "Histone H2A type 2-B", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTESHK---------------------PGKNK----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A9UMV8-1", "uniprot_id": "H2AJ_RAT", "id": "A9UMV8-1", "name": "Histone H2A.J", "aln": "--------MSG-RGKQGGKVRAKAKSRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKKTESQ----------------------KVKSK----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64523-1", "uniprot_id": "H2A2C_MOUSE", "id": "Q64523-1", "name": "Histone H2A type 2-C", "aln": "--------MSG-RGKQGGKARAKAKSRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESH----------------------KAKSK----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AA54CQH7-1", "uniprot_id": "A0AA54CQH7_DANRE", "id": "A0AA54CQH7-1", "name": "Histone H2A", "aln": "--------MSG-RGKTGGKARAKAKTRSSRAGLQFPVG-RVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEILELAGNAARDNKKTR-IIPRHLQLAVRNDEELNKLLGGVTIAQGGVLPNIQAVLLPKKTEKAESYAIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P84051-1", "uniprot_id": "H2A_DROME", "id": "P84051-1", "name": "Histone H2A", "aln": "--------MSG-RGK-GGKVKGKAKSRSNRAGLQFPVG-RIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTEKKA------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q4AB57-1", "uniprot_id": "Q4AB57_DROME", "id": "Q4AB57-1", "name": "Histone H2A", "aln": "--------MSG-RGK-GGKVKGKAKSRSDRAGLQFPVG-RIHRLLRKGNYAERVGAGAPVYLAAVMEYLAAEVLELAGNAARDNKKTR-IIPRHLQLAIRNDEELNKLLSGVTIAQGGVLPNIQAVLLPKKTEKKA------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M0R7B4-1", "uniprot_id": "M0R7B4_RAT", "id": "M0R7B4-1", "name": "", "aln": "MSETAPAAPAAPAPVEKTPVKKKAKKTSSAAGKRKASGPPVSELITKAVAASKERSG--VSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGILVQTKGTGASGSFKLNKKASSGEAKPKAKKVGAAKAKKPAGSAKKPKKATGSATPRKTKKTPKKAKKPGATAGAKKVSKSPKKVKAAKPKKAAKSPAKAKAPKAKATKPKASKPKANKAKKAAPRKK----", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . ::. * ** . * : .*: :. :.: :* * ::*: : *:* :: * :* : : ::.: : : :. ..: . :.* . *: : .* . ", "identical_positions": 15, "similar_positions": 45, "identity": "6.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-154", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6GQS1-1", "uniprot_id": "SCMC3_MOUSE", "id": "Q6GQS1-1", "name": "Mitochondrial adenyl nucleotide antiporter SLC25A23", "aln": "-------------------------------------------------------------------------------------------------------MRGGSSDAERRQRWGRLFEELDSNKDGRVDVHELRQGLARLGRGDPD--RAQQGVSSDWDADPDGGLSLEEFTRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRAL----------------------------------------GISISLEQAEKILHSMDRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSQEEKLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKSNRLN---------------------ILGGLRNMIQEGGVLSLWRGNGINVLKIAPESAIKFMAYEQIKRAIR---GQQE--TLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLR-RTGQYKG---LLDCAKRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNRWLQQYSHESANPGILVLLGCGTISSTCGQIASYPLALVRTRMQAQASIEGGP-----------------QVSMVGLLRHILSQEGVWGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JVD2-1", "uniprot_id": "A0A0G2JVD2_RAT", "id": "A0A0G2JVD2-1", "name": "Mitochondrial adenyl nucleotide antiporter SLC25A23", "aln": "-------------------------------------------------------------------------------------------------------MRGGSGDAERRQRWGRLFEELDSNKDGRVDVHELRQGLARLGRGDPD--RAQQGISSDWDSDADGGLSLEEFTQYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRAL----------------------------------------GFSISMEQAEKILHSMDRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSKQEKLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKSNRLN---------------------ILGGLRNMVQEGGLLSLWRGNGINVLKIAPESAIKFMAYEQIKRAIC---GQQE--TLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLR-RTGQYKG---LLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNRWLQQYSHESANPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGP-----------------QVSMVGLLRHILSQEGVWGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BV35-1", "uniprot_id": "SCMC3_HUMAN", "id": "Q9BV35-1", "name": "Mitochondrial adenyl nucleotide antiporter SLC25A23", "aln": "-------------------------------------------------------------------------------------------------------MRGSPGDAERRQRWGRLFEELDSNKDGRVDVHELRQGLARLGGGNPDP-GAQQGISSEGDADPDGGLDLEEFSRYLQEREQRLLLMFHSLDRNQDGHIDVSEIQQSFRAL----------------------------------------GISISLEQAEKILHSMDRDGTMTIDWQEWRDHFLLHSLENVEDVLYFWKHSTVLDIGECLTVPDEFSKQEKLTGMWWKQLVAGAVAGAVSRTGTAPLDRLKVFMQVHASKTNRLN---------------------ILGGLRSMVLEGGIRSLWRGNGINVLKIAPESAIKFMAYEQIKRAIL---GQQE--TLHVQERFVAGSLAGATAQTIIYPMEVLKTRLTLR-RTGQYKG---LLDCARRILEREGPRAFYRGYLPNVLGIIPYAGIDLAVYETLKNWWLQQYSHDSADPGILVLLACGTISSTCGQIASYPLALVRTRMQAQASIEGGP-----------------QLSMLGLLRHILSQEGMRGLYRGIAPNFMKVIPAVSISYVVYENMKQALGVTSR--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TVL2-1", "uniprot_id": "A0AB32TVL2_DANRE", "id": "A0AB32TVL2-1", "name": "", "aln": "---------------------------------------------------------------------------------------------MWPRGWTQARCQDSGVDQDREQLWAELFQQLDLNKDGRVDVNELRIGLAARGLSWSS---VEEQIVRAGDINHDGQLDFEEFTEYLRSHEKRLRLMFRSLDRNNDGEVDVGEIQQSLHNL----------------------------------------GVDITLEQAAKILQSMDKDHSMTIDWIEWRDHFLFNPLHNMEEIAQFWKHSVMLDIGEHLTVPDEFSEKEKRSGFVWRQLMAGAVAGSVSRTGTAPLDRLKVFLQVHGQSSDKGN---------------------VWSGLRAMVKEGGLTALWRGNGINVLKIAPETAIKFLAYEQIKRLMR---GSNEGGTLKVHERFVAGSLAGATAQTIIYPMEVLKTRLTLR-KTGQYSS---VADCAKQILQKEGVRAFYKGYLPNMLGIIPYAGIDLAVYETLKNAWLQRHTEGSADPGVLVLVGCGTVSSTCGQLASYPLALIRTRMQAQASIKGAP-----------------QLSMLTLFRSIVAQEGVVGLYRGIAPNFLKVIPAVSISYVVYEHMRALIFRFTGYVPVDAVK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8BVN7-1", "uniprot_id": "S2541_MOUSE", "id": "Q8BVN7-1", "name": "Calcium-independent mitochondrial carrier protein SCaMC-3L", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MGVH----------------------------------------------------------------------------------------------------------------------------------------LEVLDTGEQLMVPVDVLEEEN-KGTLWKFLLSGAMAGAVSRTGTAPLDRARVYMQVYSSKSNFRN---------------------LLSGLRSLVQEGGVRSLWRGNGINVLKIAPEYAIKFSVCEQSKNFFY---GVHS--SQLFQERVVAGSLAVAVSQTLINPMEVLKTRLTLR-FTGQYKG---LLDCARQILERDGTRALYRGYLPNMLGIIPYACTDLAVYELLQCLWQKL-GRDMKDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGS------------------NPTMQGVFKRILSQQGWPGLYRGMTPTLLKVLPAGGISYLVYEAMKKTLGVQVLSR------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N5S1-1", "uniprot_id": "S2541_HUMAN", "id": "Q8N5S1-1", "name": "Mitochondrial carrier protein SCaMC-3L", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MGAQPGEPQNTCSRIQTLFRRVKTLLIKAPPPPQPPPPPPSWNPGCTHVY----------------------------------------GYAFGHMHDNNLEH---------------------------------LPSQQVLDTGEQLMVPVEVLEVDN-KEALWKFLLSGAMAGAVSRTGTAPLDRAKVYMQVYSSKTNFTN---------------------LLGGLQSMVQEGGFRSLWRGNGINVLKIAPEYAIKFSVFEQCKNYFC---GIQG--SPPFQERLLAGSLAVAISQTLINPMEVLKTRLTLR-RTGQYKG---LLDCARQILQREGTRALYRGYLPNMLGIIPYACTDLAVYEMLQCFWVKS-GRDMGDPSGLVSLSSVTLSTTCGQMASYPLTLVRTRMQAQDTVEGS------------------NPTMRGVLQRILAQQGWLGLYRGMTPTLLKVLPAGGISYVVYEAMKKTLGI-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0E8F2-1", "uniprot_id": "SCMC_DROME", "id": "Q0E8F2-1", "name": "Mitochondrial adenyl nucleotide antiporter SCaMC", "aln": "MVRKQVGIENSASLAVSKQQDQKEQDYKPEDQKQQHIDIDLTPDPASNFNFAQQAQANYSARTLAASYEHGQNLGLQHAHLATSSTTNTPLAYDLHEVASSGSILPTEIPIEDEERLERIFNKLDRDGDGRIDIHDLSAALHEFGLSSVY----AEKFLQQSDKDQSGNVGFAEFLHYVREHEKNLVLQFSHLDKNRDGKVDLEELISAFKDL----------------------------------------GLDIDMDEARNLLTRMDKDGSLNISFNEWRDFMLLAPSTDIHDLIKFWRHSTYLDIGEDMNVPDDFTQKEMQTGLWWRHLVAGGIAGAVSRTCTAPLDRIKVYLQVQTQRMG------------------------ISECMHIMLNEGGSRSMWRGNGINVLKIAPETAFKFAAYEQMKRLIR---GDDGSRQMSIVERFYAGAAAGGISQTIIYPMEVLKTRLALR-RTGQYAG---IADAAVKIYKQEGVRSFYRGYVPNILGILPYAGIDLAVYETLKRRYIAN-HDNNEQPSFLVLLACGSTSSTLGQLCSYPLALVRTRLQAQAAETIANQKRKTQIPLKSSDAHSGEETMTGLFRKIVRQEGLTGLYRGITPNFLKVLPAVSISYVVYEYTSRALGIKMS--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D6W196-1", "uniprot_id": "CMC1_YEAST", "id": "D6W196-1", "name": "Truncated non-functional calcium-binding mitochondrial carrier SAL1-1", "aln": "-----------------------------------------------------------------------------------------------------MLLKNCETDKQRDIRYACLFKELDVKGNGQVTLDNLISAFEKNDHPLKGNDEAIKMLFTAMDVNKDSVVDLSDFKKYASNAESQIWNGFQRIDLDHDGKIGINEINRYLSDLDNQSICNNELNHELSNEKVNKFSRFFEWAFPKRKANIALRGQASHKKNTDNDRSKKTTDSDLYVTYDQWRDFLLLVPRKQGSRLHTAYSYFYLFNEDVDLSSEGDVTLINDFIRGFG-FFIAGGISGVISRTCTAPFDRLKVFLIARTDLSSILLNSKTDLLAKNPNADINKISSPLAKAVKSLYRQGGIKAFYVGNGLNVIKVFPESSIKFGSFEVTKKIMTKLEGCRDTKDLSKFSTYIAGGLAGMAAQFSVYPIDTLKFRVQCAPLDTKLKGNNLLFQTAKDMFREGGGQIILQRCHSRYSGHISLCCIRFGDFFCLKKMVYCQTGKDPEP---------TTRSGHSKQPGCTSNGCIQWNCRSFCCLSNQS-------------------------------------FKNKTTSPRNICTSLCV-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: . : :. : :::*.::* :*** ***:** :*:: . . . : :: : :** ::: ***:**:*: ** ::** * *. : * . **. * :* : *::.** *: : . : : * : .. * : : : .. * :. . :. : *: : * * . . :: . :: ::. :.. :: .: : ", "identical_positions": 40, "similar_positions": 83, "identity": "6.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-166", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BY79-1", "uniprot_id": "S35G1_MOUSE", "id": "Q8BY79-1", "name": "Solute carrier family 35 member G1", "aln": "MGPPESAAELAAEAVELREPELQLADPASPG--EEHVDVEAEGAPGRGRCWPCGAWACGSRGEPEAKKKAP-CPGLGLFYTVLSAFLFSVASLFVKKVQGVHAVEISAFRCVVQMLVIIPCLIYRKTGFIGPKGQRLFLFLRGVFGSSAMILMYYAFQTTSLADATVIAFSCPVFTSIFAWIFLKEKYSLWDAFFTLFAIAGVILIVRPPFIFGSDTSGMRESYSEHIKGTFAAIGHAVLAAITLVILRKMGKSVDYFLSIWYYVILGLPEAIIILFVIGEWSLPYCGLDRLFLILIGLLGLGGQIFITKAVQIEKAGLVAIMKTMDIVFAFIFQIAFFDNVPTWWTVGGALCVVVSTTGATIRRWLQGSK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2M3R5-1", "uniprot_id": "S35G1_HUMAN", "id": "Q2M3R5-1", "name": "Solute carrier family 35 member G1", "aln": "MRPQDSTG-----VAELQEPGLPLTDDAPPGATEEPAAAEAAGAPDRGRCWLCLSSPCCSRTEPEAKKKAP-CPGLGLFYTLLSAFLFSVGSLFVKKVQDVHAVEISAFRCVFQMLVVIPCLIYRKTGFIGPKGQRIFLILRGVLGSTAMMLIYYAYQTMSLADATVITFSSPVFTSIFAWICLKEKYSPWDALFTVFTITGVILIVRPPFLFGSDTSGMEESYSGHLKGTFAAIGSAVFAASTLVILRKMGKSVDYFLSIWYYVVLGLVESVIILSVLGEWSLPYCGLDRLFLIFIGLFGLGGQIFITKALQIEKAGPVAIMKTMDVVFAFIFQIIFFNNVPTWWTVGGALCVVASNVGAAIRKWYQSSK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B4E3-1", "uniprot_id": "A0A8M3B4E3_DANRE", "id": "A0A8M3B4E3-1", "name": "Solute carrier family 35 member G1", "aln": "MRT----------LSEVPDGDAGESRPVNRGAFYRVCLPACCKRSDTHRDEDEDDGEEDTGENTVQKEKQPSCPGLGLMYSLLASVFFSIAALLVKKMEGMHAIQISAIRCFFQMLFVLPAMIYYKTGFLGPRGMRIYLFLRGFLGSNAMILLYYAVLQMPLADATVIMFSNPVFTALLAWIFLKERCTIWDVVFTVFTLTGVILIARPPFLFGGELSGIEGDYSSHIKGTVAAFSGAVGAACTMVILRKIGKRVHYFLSVWYYAVLGLIECVVVLFILDEWTIPSCGWDRWTLMAIGVLGIAGQAFLTKALQIEKAGPVALMRTMDVVLAFVLQFLFLNRKPTWWSLGGALCVISSTSGVALRKWYNSTRQKS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . *: : : . * . . .. * : :. *:* * ******:*::*::.:**:.:*:***::.:**::***:**..***.::*.:** ****:**:* *::*:***.:**.**:*:*** .******* ** ****:::*** ***: : **..**:*:::*****.****:**.: **:. .** *:***.**:. ** ** *:*****:** *.****:***.:*** *.:::* ::.**::* ** ** *: **::*:.** *:***:****** **:*:***:*:**::*: *::. ****::******: *. *.::*:* :.:: ", "identical_positions": 172, "similar_positions": 115, "identity": "45.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-168", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V6A9-1", "uniprot_id": "G3V6A9_RAT", "id": "G3V6A9-1", "name": "Microfibril-associated glycoprotein 4", "aln": "MSLSLNLEVMGLGRLVALQLRTALPSAGIAGMLCLYPCLCAACAGGPQRPESASDLLGLELEVPGTCQTLSGLPLLLLLLSTPPPCAPQASGIRGDALEKSCLQQPLDCDDIYMQGYQEDGVYLIYPYGPSVPVPVFCDMTTEG-----GKWTVFQKRFNGSVSFFRGWNDYKLGFGRADGEYWLGLQNLHLLTLKQKYELRVDLEDFENNTAYAKYVDFSISPNAVSAEEDGYTLYVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRSCH----FANLNGFYLGG--SHLS-YANGINWAQWKG-FYYSLKRTEMKIRRA-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D1H9-1", "uniprot_id": "MFAP4_MOUSE", "id": "Q9D1H9-1", "name": "Microfibril-associated glycoprotein 4", "aln": "------------------------------------------------------------------MKALPALPLMLMLLSMPPPCAPQASGIRGDALEKSCLQQPLDCDDIYAQGYQEDGVYLIYPYGPSVPVPVFCDMTTEG-----GKWTVFQKRFNGSVSFFRGWSDYKLGFGRADGEYWLGLQNLHLLTLKQKYELRVDLEDFENNTAYAKYIDFSISPNAISAEEDGYTLYVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRSCH----FANLNGFYLGG--SHLS-YANGINWAQWKG-FYYSLKRTEMKIRRA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55083-1", "uniprot_id": "MFAP4_HUMAN", "id": "P55083-1", "name": "Microfibril-associated glycoprotein 4", "aln": "------------------------------------------------------------------MKALLALPLLLLLS--TPPCAPQVSGIRGDALERFCLQQPLDCDDIYAQGYQSDGVYLIYPSGPSVPVPVFCDMTTEG-----GKWTVFQKRFNGSVSFFRGWNDYKLGFGRADGEYWLGLQNMHLLTLKQKYELRVDLEDFENNTAYAKYADFSISPNAVSAEEDGYTLFVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRSCH----FANLNGFYLGG--SHLS-YANGINWAQWKG-FYYSLKRTEMKIRRA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "R4GEQ7-1", "uniprot_id": "R4GEQ7_DANRE", "id": "R4GEQ7-1", "name": "", "aln": "-----------------------------------------------------------------MAMTVFVVALLSVFT------ASVVSGFK-----------PFDCSEIYKSGQTVSGIYSIYPAG-DTPVWVYCQMVSDGKVEENEGWTVFQRRMDGSIHFFQLWEKYRIGFGTTEGEYWLGLENLYQLTRHKKFMLRVDLEDFTGRRGFAQYSSFSVG-----SEVEGYKLELSGFTDGGAGDSLSYHNGMKFSTYDRDQDTNEDNCARMRLGAFWYKGCN----YANPNGVYLWG--EDKSKNGIAINWYTWKNDNETPMKFITMKIKPVS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K7T3-1", "uniprot_id": "A0A0B4K7T3_DROME", "id": "A0A0B4K7T3-1", "name": "Fibrinogen C-terminal domain-containing protein", "aln": "------------------------------------------------------------MKPICFALCVFSLGLFYLAS------AEIGENVKIQTYKKY----SSSCKELNPKKSGVQKIQVG-----SDVIEVYCDVTIAG-----KGWLVVQRRVSVEENFYRNWTSYQTGFGDLKGNFFIGLNNLNKISSLQPQELYIELVDFAGEKRYAHYSVFHVG-----NVYSNYPITQLGAYSGTAGDSLSYHLYQPFSTFDRDNDNATINCAARYMGAWWYRECLSRIPCSNLNGAYLGGNHTDPALFGSGIVWGEWKG-FTYSYKTVNIMVRPK-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *: : * ...: . .*.:: . . : . : *:*::. * * *.*:*.. . *:: * .*: *** .*::::**:*: :: : * ::* ** .. :*:* * :. ..* : * .* ******** ***:***:* *** **:*:: * :* ** ** * . : . .* * **. . * : :: ", "identical_positions": 63, "similar_positions": 68, "identity": "18.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-171", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0QWL6-1", "uniprot_id": "M0QWL6_MOUSE", "id": "M0QWL6-1", "name": "", "aln": "MDRARWQRMLTLLPICLALAFSLTAMGSSHWCEGIRRMTKPLCQDLLGGLNCIHFSRSSSSTGSKHDDSQAVQYIWETGDDKFIQRRFHAGLWQSCEESLNSTGERCRCFLGIVPAEGQGVLWLSIGAEVLDIFLILTGVILLGFSMSCYSSGCSWLNVDASVAILMVLAGLLGMVAHMMYTTSFQITVNLGPEDWRPQTWDYGWSYCLAWGSFALCMAVSVATMSRYTTAQAEVP---RAQKGGPYPQHNTPQPGPSRKVWQTGATPHP-VGHIFTNVPGHPPPGTGGKVSMC-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MUP6-1", "uniprot_id": "GS1L2_HUMAN", "id": "A8MUP6-1", "name": "Germ cell-specific gene 1-like protein 2", "aln": "MDRAKQQQALLLLPVCLALTFSLTAVVSSHWCEGTRRVVKPLCQDQPGGQHCIHFKRDNSSNGRMDNNSQAVLYIWELGDDKFIQRGFHVGLWQSCEESLNGEDEKCRSFRSVVPAEEQGVLWLSIGGEVLDIVLILTSAILLGSRVSCRSPGFHWLRVDALVAIFMVLAGLLGMVAHMMYTTIFQITVNLGPEDWKPQTWDYGWSYCLAWGSFALCLAVSVSAMSRFTAARLEFTEKQQAQNGSRHSQHSFLEPEASESIWKTGAAPCP-AEQAFRNVSGHLPPGAPGKVSIC-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QA75-1", "uniprot_id": "F1QA75_DANRE", "id": "F1QA75-1", "name": "Germ cell-specific gene 1-like protein", "aln": "MMERRRRASLALLLNLLALLLAVSALSSSYWCDGERKVVKPFCTGPVTG-KQTHCIRYNSSN---ANDSRLVQYIWETGEDKFVLRKFHTGIWFSCEQNVDLVGEKCRSFITVAPPHERGVLWLCIVAECLYILLLATGGILMSIEVCHIGNVIDGLKLNAFAAIFTVLSGLLGMVAHMMFTTAFQLTVSLGPEDWKPQHWDYSWSYILAWSSFTACMASSVTTINRYTKTILEFKHKRRNMEKNLKIKQKLLDLESPEQVWDMFISSVPSSAEEFLDLSASGRKLSAGSVFLDLNELPSPQGEEYC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : : * ** *** ::::*: **:**:* *::.**:* . * : * * .**. ::*: * **** *:***: * **.*:* ***:.:: .*:**.* :.*.. :*****.* .* * *.*: *. **:. :. . *.::* .**: **:**********:** **:**.******:** ***.*** ***.**: *:* **:::.*:* : *. : : . ::. : ....:*. :. * . * ::.. : *.* : ", "identical_positions": 111, "similar_positions": 91, "identity": "36.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-173", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V882-1", "uniprot_id": "EPN3_RAT", "id": "Q4V882-1", "name": "Epsin-3", "aln": "---------MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMVWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGMG-----IGSGQLGFSR-------RSRGSPSSYTSASSSPRYASDLEQARPQTSGEEELQLQLALAMSREEAE---------------------------KGGRSWKGDDFPVANGAEPAGQRR-RDREPEREERKEEEKLKTSQSSILDLADVFAPAPALPSTHCSADP---------WDIPGLRPNTEPSGSSWG---PSADPWSPVPSGNALSRSQPWDLLPTLSS-SEPWGRTPVLPSGPPITDP--WAPSSPTPKLPSTGVDPWG---------------ASVETSNTSALGGASPFDPFAKPLESTEPMESRDSAQALP----KGKSPSPVELDPFGDSSPSCKQNGVKE--TEALDLGVLG--------------------------------------EALTQQPGKEARPCRTPESFLGPSASSLVNLDSLVKAPLAARTRNP-----FLTGLSAPSPTNPFGAGEQGRPTLNQMRTGSPALGLPPGGPVGVPLGSMTYSASLPLP-LSSVPVGATLPASVSVFPQAGAFAPPPA-----SLPQPLLPTSDPVG--PLPPQ---AGTNPFL--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91W69-1", "uniprot_id": "EPN3_MOUSE", "id": "Q91W69-1", "name": "Epsin-3", "aln": "---------MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFAEVMGMVWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGMG-----IGSGQLGYSR-------RSRGSPSSYTSASSSPRYASDLEQARPQTSGEEELQLQLALAMSREEAERPVPPASHRDEDLQLQLALSLSRQEHEKGVRSWKGDDSPVANGAEPAGQRRQRDREPEREERKEEEKLKTSQSSILDLADIFAPAPALPSTHCSADP---------WDIPGLRPNTEPSGSSWG---PSADPWSPVPSGNALSRSQPWDLLPTLSS-SEPWGRTPVLPSGPPIADP--WAPSSPTRKLPSTGADPWG---------------ASMETSDTSALGGASPFDPFAKPLESTEPKESRDSAQALP----TGKSPSTVELDPFGDSSPSCKQNGMKE--PEALDLGVLG--------------------------------------EALPQQPGKEARPCRTPESFLGPSASSLVNLDSLVKAPLAARTRNP-----FLTGLGVPSPTNPFGAGDQGRPTLNQMRTGSPALGLPPGGPVGAPVGSMTYSASLPLP-LSSVPVGATLPASVSVFPQAGAFAPPPA-----SLPQPLLPTSGPMG--PLPPQ---AGTNPFL--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H201-1", "uniprot_id": "EPN3_HUMAN", "id": "Q9H201-1", "name": "Epsin-3", "aln": "---------MTTSALRRQVKNIVHNYSEAEIKVREATSNDPWGPPSSLMSEIADLTFNTVAFTEVMGMLWRRLNDSGKNWRHVYKALTLLDYLLKTGSERVAHQCRENLYTIQTLKDFQYIDRDGKDQGVNVREKVKQVMALLKDEERLRQERTHALKTKERMALEGIG-----IGSGQLGFSRRYGEDYSRSRGSPSSYNSSSSSPRYTSDLEQARPQTSGEEELQLQLALAMSREEAEKPVPPASHRDEDLQLQLALRLSRQEHEKEVRSWQGDGSPMANGAGAVVHHQ-RDREPEREERKEEEKLKTSQSSILDLADIFVPALAPPSTHCSADP---------WDIPGFRPNTEASGSSWG---PSADPWSPIPSGTVLSRSQPWDLTPMLSS-SEPWGRTPVLPAGPPTTDP--WALNSPHHKLPSTGADPWG---------------ASLETSDTP--GGASTFDPFAKPPESTETKEG--LEQALP----SGKPSSPVELDLFGDPSPSSKQNGTKE--PDALDLGILG--------------------------------------EALTQ-PSKEARACRTPESFLGPSASSLVNLDSLVKAPQVAKTRNP-----FLTGLSAPSPTNPFGAGEPGRPTLNQMRTGSPALGLA-GGPVGAPLGSMTYSASLPLP-LSSVPAGLTLPASVSVFPQAGAFAP-----------QPLLPTPSSAGPRPPPPQ---TGTNPFL--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UTI6-1", "uniprot_id": "A0A8N7UTI6_DANRE", "id": "A0A8N7UTI6-1", "name": "", "aln": "---------MTTSALRRQVKNIVHNYSDAEIKVREATSNDPWGPSSSLMSEIAELTFSVVAFSEVMAMVWKRLNDHGKNWRHVYKALTLLDYLAKTGSERVAQQCRENAFTIQTLRDFQYVDRDGRDQGVNVREKAKQLVALLRDEDRLRAERAQALKTKERMMAAGAPPAYPSRRSSQPSMAALYGEEFNHSRGSPSSFNSSSSSPR-ASDLEQTRPQTSGEEELQLQLALAMSR-------------------------------EDQRSRHGDDPPVQ-----------QEREGERHSGPPE-------SAMMDLVDIFSSTPTGP---LRDES---------WDAPSSCP---ATADPWG---PSA----VVKSNNPVAGS-PWMARPSSSSPARQWG------TRQSPTNP--WDAP------PSNSTSTMD---------------EKVWRSPARLVSGRDPFS-IPEEEELQVEEEGLPLEREGPNRVFSPRCESPADGDQFGELVLGVHVNGRENDSPEAFDLSRLG--------------------------------------PPLDT---ATRRQCRTPEAFLGPTAASLVNLDTLIPTNPPVKSKNP-----FLSGLSTPSPTNPFHCEQP-RLTLNQMRPHS---------TSPLPAHALSYSASLPLPNLQHKPQ--TLPSSFTQPHHG--LLELPS-----NLPQPLLPLT-PVPLPPSSRQRLQQSHNPFL--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VS85-1", "uniprot_id": "Q9VS85_DROME", "id": "Q9VS85-1", "name": "", "aln": "MRKQKDDMQVNVAGLRRNIKNLAHNYSDAQVKVREATSNDPWGPSAAIMSEIAELTYNVVAFSEIMQMIWKRLNDHGKNWRHVYKALILLEYLIKTGSEKVAQQCKENIFAIQTLREFVYFE-EGKDQGTHVREKAKQLVTLLKDDERLKNERVKAQKAKERFAQNPSG-----FGSDGYIDGP-------SQRDLPPGWQEEP--PKSVSELEMVRPQTAGEEELQLQLAMAMSREEAE---------------------------QEEAKRRSDDVRLQLALSQSE----QDFKDPNGRPIPAPKKEEQQSHLLDLLDISLGATSISSPPLGAAGGAPTAVVDPWAMPGPRAPSQLSDPWSGTSSPQVDPWNPSAAPRTILGAGVPMTSAPLGAGNDAWGARTQSPSVASGSSNEGWLQSNGNANQNGRGATPAGPPAEGWLIKSTAVGALGAAPINHAANNGSSSSDPWLAEPAASAAGGAAAVGLADP---WAPGAASQTGAGALDDPWKALGTGAIKKQSPEFDEFDLITNRNKSEHSNSNASNNNNASLLDDMDPLSANYGNGGINSSMHPSTGATAKKSIKDAHSFLG-ENSALVNLDNLIKPIAPQTQTGNQPAYNPFSDNVVPPKTNLFQQQQPAVPSINQLKQQAPFSVSMNQDPWAPVMGGVSTTSQPKLPPPVRPTSLNLGPSSVGEFQLLSALSNPIIPIAHIPQPQPNLQVYNNAYQSSSSTNILGKSNIPTNMNSSTSNSTIHSCYASPSPGVDGIRNMDIFTERPYYNSPTAPADDTYMYNSRDNNNINSNYGTPSLYSSFAASYSSALSDSLAETPGISVAPLGFVADTVMSFGPSSSSANCKLEQNNNMPWIKPEAATNPFLS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..:.***::**:.****:*::*************.:::*****:**:..***:*:* *:*:**** *********** **:** *****:**:**:** ::****::* *.: :*:***.:****.**:::**:*::**: **.:* *:***: *. . .*. *..: . . *: .*:** .****:**********:**** : . :.*. : :: : . * ::** *: : : . * *. . : * *.. : : : . .: ** : . :. * . .. . . .* .. . . * * . . :.: . .. :: .: ::. : : : ..:*** ::*****.*: . . ::. .*. ** * : ::**:: : . .:: ::. ** . *:*. : ** * . . : . * ", "identical_positions": 158, "similar_positions": 159, "identity": "17.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-179", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W2C8-1", "uniprot_id": "Q9W2C8_DROME", "id": "Q9W2C8-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNRAWLCLLICLALSCGPSQSASQ-DRATN-QTAASPLLKQSQNTFIQWVLSLLPQRPGSSDSENATL--------ATLSSSSMMPDAASTTSTTTPAPSSSTTTTRRATTPAPPTLNPPRNCSDCVCGIANIQKRIVGGQETEVHQYPWVAMLLY---GGRFYCAASLLNDQFLLTASHCVYGFRKERISVRLLEHDRKMS-HMQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFN-EVLHPVCMPTPGRSFKGENG-IVTGWGALKVGG--PTSDTLQEVQVPILSQDECRK-SRYG-NKITDNMLCGGYDE-GGKDSCQGDSGGPLHIVASGTR-EHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWIKNLTKQACLCQQ-----------------------------------ETKKIK-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7V4-1", "uniprot_id": "Q9I7V4_DROME", "id": "Q9I7V4-1", "name": "Peptidase S1 domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCNFHLLLILATALGDLACATPSL-RSASDPEKILNNLAQLRQSSFLDWIQSILG--------------------------------------PEVPAEWSS---------PAK------RECAECSCGNINTRHRIVGGQETEVHEYPWMIMLMW---FGNFYCGASLVNDQYALTAAHCVNGFYHRLITVRLLEHNRQDS-HVKIVDRRVSRVLIHPKYSTRNFDSDIALIRFNEPVRLG-IDMHPVCMPTPSENYAGQTA-VVTGWGALSEGG--PISDTLQEVEVPILSQEECRN-SNYGESKITDNMICAGYVEQGGKDSCQGDSGGPMHVLGSGD--AYQLAGIVSWGEGCAKPNAPGVYTRVGSFNDWIAENTRDACSCAQPEAAGEPASPMETTEQGDQENTTANGAAEADPEVEEANKLI-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KVM3-1", "uniprot_id": "Q7KVM3_DROME", "id": "Q7KVM3-1", "name": "Peptidase S1 domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKLPWILIALFCGLCSGSTERRIRPNEGKIFEWLGSILLPSTTTTTSTPVVATTS------------------------------------TTTRRTTTTSSTTSRTTTSRTTVANFPIERDCVTCRCGLINTLYKIVGGQETRVHQYPWMAVILI---YNRFYCSGSLINDLYVLTAAHCVEGVPPELITLRFLEHNRSHSNDDIVIQRYVSRVKVHELYNPRSFDNDLAVLRLNQPLDMRHHRLRPICLPVQSYSFDHELG-IVAGWGAQREGG--FGTDTLREVDVVVLPQSECRNGTTYRPGQITDNMMCAGYISEGGKDACSGDSGGPLQTTFDEQPGQYQLAGIVSWGVGCARPQSPGVYTRVNQYLRWLGSNTPGGCHCMP---------------------------------YPEEDY---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VR15-1", "uniprot_id": "Q9VR15_DROME", "id": "Q9VR15-1", "name": "Peptidase S1 domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRVYLALPLLLLGIGLSLAQYQYQAPHQTLAQQFADVVD--VVDPAEQSIKAVRP--------------------------------------PKSRNQCTAK--------------------QNCFCGTPNVN-RIVGGQQVRSNKYPWTAQLVKGRHYPRLFCGGSLINDRYVLTAAHCVHGNRDQ-ITIRLLQIDRSSR--DPGIVRKVVQTTVHPNYDPNRIVNDVALLKLESPVPLT-GNMRPVCLPEANHNFDGKTA-VVAGWGLIKEGG--VTSNYLQEVNVPVITNAQCRQ-TRYK-DKIAEVMLCAGLVQQGGKDACQGDSGGPLIVN-EGR---YKLAGVVSFGYGCAQKNAPGVYARVSKFLDWIRKNTADGCYCQS------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A4D6K1E7-1", "uniprot_id": "A0A4D6K1E7_DROME", "id": "A0A4D6K1E7-1", "name": "Peptidase S1 domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLKYIIFFWMLTANYSSVLSLEYSKGFNESDAINTIHTGHNKRTSKFLFDTIFR----------------------------------------ISSGVSNAFGLSDTEDEVEYTENSSLKNCDCDCGFSNEEIRIVGGKPTGVNQYPWMARIVY---DGKFHCGGSLLTKDYVLSAAHCVKKLRKSKIRVIFGDHDQEITSESQAIQRAVTAVIKHKSFDPDTYNNDIALLRLRKPISFS-KIIKPICLPRYNYDPAGRIG-TVVGWGRTSEGG--ELPSIVNQVKVPIMSITECRN-QRYKSTRITSSMLCAGRPS---MDSCQGDSGGPLLLSNGVK---YFIVGIVSWGVGCGREGYPGVYSRVSKFIPWIKSNLENTCLCS-------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0AC58GWS1-1", "uniprot_id": "A0AC58GWS1_DANRE", "id": "A0AC58GWS1-1", "name": "", "aln": "MESLKSLMIIFLISGMGKAVTAQSCGVSPLNSPGGNVSAGNVTWPWQADLYYFGYRLCGGSLISHEWVLTAAHCVYYIPKSYITVYLGRNSQNASDSNANRVTLSAQSIIIHPDFDSLQFTNDIALLRLAKPVNFTSSISPICLAANDSVFHNGTTCWATGWSYNQDTPSSYGTLPVVMVKVVGNKECDCRYQDIQLYWDITITQTTMCTSGETGYGACSGQLGDPLQCMQGSVWILAGVTNFGFCGTGVAPDVYSKVSEFQSWILNNVNGSDIGLETFKSDGEDKDNSFLCNGEDTVSGLFYPFGNGDTENPSQDHGHSPVVFQKPFVYFGRVYEQTYVNNNGCLTFAGPFSEPIPNVILSKLNRDIIAPFWTNMDNTVNGSISYRQLTKGGLLVAASNDINQYFPHLNFTAYWIFIATWDKVPYFNDSQSSSSFQVILVSGGSLSFVMINYGNISSTDQWFQAGYGTMNLTNYFSVPIPTANKLSNSSNVNLSGRWAFRVDGGPEEGLFYPHGDEDIKNPAEDFGSSPLIHLAQPFNYFGLIYNRLYVNNKGYLTFKEPFYQYYPNLFTAYYSTRDIIAPLWTDIDITRNGAISYRQVTDGHVLNRASRDVNQYFPNLNFSASWVFIATWDKVPYYGYRRSVSTFQIVLVSGKNMSFILMHYGSISQAPYQVQSGYDTTDSTDFFLIPVSDPKLLPYTSNVNMLGRWAFRIDNTSANNGLFCPFRNGYKVNMYYGYWISLPTPFPYYGLRHRLVKIHKNGFFTFNFQQEESTQAIPAYGFTDTVAPLWTEIDESDVYIKHFTGDRILQLVTKNINQYFPAFTADVVYSCTWDNVRFSNTSISQSSTFQVLLITGSGLSFIIFNYANIPQIKHIALAGFDTADSIVYYKIPVSNITDLSHSTNVNFTGRWAFRVDTLTTEYGLFYPTKDSKLYCQSNADSHLQYLRSPFLYFKRKYYNISVNCNGYLTFNESFNEGSPKAFPGNSTRDIIAPLWTEFDSSVDTSVSYRIVNQGRILERATTEIKQYFPLFGFSVHTVLIATWNRVPYYNSSLSDSSFQVVLVMCRTFSFVIMNYGNISSTGQRFQAGYDTINSTNYFSIPLPDQNKLSKSSNVNVPGRWVFRVDGRSNEEIFYPYGDAEDEINPQSDDGSSPPIPLLQSFVYFGNTYDTIFVNNNGDLTFDKPLHQYNPDNFPAYSTRDIIAPLWTDINNGMEGTISYRQVTNGDILNRASKDINRYFPNLNFSASWVFIATWDKVPYYGYRESESTFQVVLVSDKKRSFTLMHYDYITYTQSAESGYDTNGSTVFYSIPVSDVTNLPYTSNVNVKGRWVFRVDNSSEVKGSCINTNSQALDSPSAAVCGIIPVNSSNGTVGGQNSSAVHWPWQASLYW---YSGQTCGGSLINKEWVLSAAHCFNGQRNGFYLTVILGPKTQNKYDPSRISRSVKAVIKHPYYNPNTNDNDIALVRLSFPITFT-DSIRPVCLAAEGSVFNSDTESWITTWRNISDGVPLPSPKIFQEVEVPVIGNRQCNC--LYGVGSITDNMICAGLLK-EGKDLCQGDSGGPMVSNQSSV---WVQSGIVSFGSGCAQSEFPGVYTRVSRYQEWITYFTCSDPPGFVQFTSTGADPDYCYSCPGRPLLCNASAVVEQQKQLSAASISHNYMLSYFWLFLALASLFIM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . * * ***: .:** : *..**:.. : *:*:**. : . . : * * . * :.. .*:*:::: *: : ::*:*:. . :. * * .. ..:*.* :: :*. * *:. *:*.* . * *.******: *:**:* **.: ****:**. : *: ", "identical_positions": 53, "similar_positions": 65, "identity": "3.15%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-183", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55083-1", "uniprot_id": "MFAP4_HUMAN", "id": "P55083-1", "name": "Microfibril-associated glycoprotein 4", "aln": "MKALLALPLLLLLS--TPPCAPQVSGIRGDALERFCLQQPLDCDDIYAQGYQSDGVYLIYPSGPSVPVPVFCDMTTEG-----GKWTVFQKRFNGSVSFFRGWNDYKLGFGRADGEYWLGLQNMHLLTLKQKYELRVDLEDFENNTAYAKYADFSISPNAVSAEEDGYTLFVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRS-CHFANLNGFYLGGSHLS-YANGINWAQWKG-FYYSLKRTEMKIRRA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D1H9-1", "uniprot_id": "MFAP4_MOUSE", "id": "Q9D1H9-1", "name": "Microfibril-associated glycoprotein 4", "aln": "MKALPALPLMLMLLSMPPPCAPQASGIRGDALEKSCLQQPLDCDDIYAQGYQEDGVYLIYPYGPSVPVPVFCDMTTEG-----GKWTVFQKRFNGSVSFFRGWSDYKLGFGRADGEYWLGLQNLHLLTLKQKYELRVDLEDFENNTAYAKYIDFSISPNAISAEEDGYTLYVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRS-CHFANLNGFYLGGSHLS-YANGINWAQWKG-FYYSLKRTEMKIRRA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9QC51-1", "uniprot_id": "E9QC51_DANRE", "id": "E9QC51-1", "name": "", "aln": "-MAMTVFVVALLSV----FTASVVSGFK-----------PFDCSEIYKSGQTVSGVYSIYPAG-DTPVWVYCQMISDGKDEENGGWTVFQRRMDGRINFYQPWEVYKRGFGTTEGEYWLGLENLYQLTRHKKFMLRVDLEDFEGRKVFAQYSSFSVG-----SEAEGYKLQVSGFTDGGAGDSLSAHNDRKFSTLDKDQDLYEKNCARYFLGGFWYTVGCHYTNPNGMYLWGEHNTRYAIGVVWSTWKNSFTLSMKTFLMKIKPVS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: .: : *: *. .**:: *:**.:** .* .*** *** * ..** *:*:* ::* * *****:*::* :.*:: *. ** *** ::*******:*:: ** ::*: *********....:*:* .**:. :* :**.* *:** ********* *..:****:*:****: :*** *.**: **::* **:** *.* : ** *: *: **. * *:* ***: . ", "identical_positions": 116, "similar_positions": 69, "identity": "43.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-195", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PPM8-1", "uniprot_id": "PP4P1_RAT", "id": "Q5PPM8-1", "name": "Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase", "aln": "MAADGERSPLLSEAGDGGAGGNGLAGPGGSATGPGGGLTPSAPPYGAGKHAPPQAFPPFPEGHPAVLPGEDPPPYSPLTSPDSGSAPMITCRVCQSPINVEGKMHQHVVKCGVCNEATPIKNAPPGKKYVRCPCNCLLICKVTSQRIACPRPYCKRIINLGPVHPGPLSPEPQPMGVRVICGHCKNTFLWTEFTDRTLARCPHCRKVSSIGRRYPRKRCICCFLLGLLLAVTATGLAFGTWKPAQQYGGIYAAWAFVILLAVLCLGRALYWGCMKVSHPVQNFS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TWL2-1", "uniprot_id": "PP4P1_MOUSE", "id": "Q3TWL2-1", "name": "Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase", "aln": "MAADGERSPLLSEAGDGGAGGNGLAGPGGSATGPGGGLTPSAPPYGAGKHAPPQAFPPFPEGHPAVLPGEDPPPYSPLTSPDSGSAPMITCRVCQSPINVEGKMHQHVVKCGVCNEATPIKNAPPGKKYVRCPCNCLLICKVTSQRIACPRPYCKRIINLGPVHPGPLSPEPQPMGVRVICGHCKNTFLWTEFTDRTLARCPHCRKVSSIGRRYPRKRCICCFLLGLLLAVTATGLAFGTWKHAQQYGGIYAAWAFVILLAVLCLGRALYWACMKVSHPVQNFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86T03-1", "uniprot_id": "PP4P1_HUMAN", "id": "Q86T03-1", "name": "Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase", "aln": "MAADGERSPLLSEPIDGGAGGNGLVGPGGSGAGPGGGLTPSAPPYGA-------AFPPFPEGHPAVLPGEDPPPYSPLTSPDSGSAPMITCRVCQSLINVEGKMHQHVVKCGVCNEATPIKNAPPGKKYVRCPCNCLLICKVTSQRIACPRPYCKRIINLGPVHPGPLSPEPQPMGVRVICGHCKNTFLWTEFTDRTLARCPHCRKVSSIGRRYPRKRCICCFLLGLLLAVTATGLAFGTWKHARRYGGIYAAWAFVILLAVLCLGRALYWACMKVSHPVQNFS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q66I51-1", "uniprot_id": "T55BB_DANRE", "id": "Q66I51-1", "name": "Type I phosphatidylinositol 4,5-bisphosphate 4-phosphatase-B", "aln": "-MADGERSPLLLDGRDGMTG----LSLGDEPYRP-----ISKP----------QNFAVFPSAPP--MLGEAPPPYSPLGSPESSSAPVISCRVCQSLISVEGKIHQHVVKCGVCNEATPIKNAPAGKKYVRCPCNCLLICKVTSQRIACPRPYCKRVINLGPVNPGAGSPNPQPTGARVSCGHCAKTFLWTEFTDRTLARCPHCRKVSSIGQRYPRKRSLICFLLCLIFVITTAGLIAGTWLKAQKYKGIYASWVFFIVLVLVTLVRALHWACMKISEPLHNYS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VT69-1", "uniprot_id": "Q9VT69_DROME", "id": "Q9VT69-1", "name": "Phosphatidylinositol-4,5-bisphosphate 4-phosphatase", "aln": "-MADPERQSLINK--DDGNGYNSVDAVDEGADNPGSNSSVATN----------EDGNGAPTAVPCIGPDELPPPYQ--QSTNTGGVPMVTCRVCQHMIDITTKREQHVVKCTHCNEATPIRNAPAGKKYVRCPCNCLLICKSSSQRIACPRPNCKRIINLAPSPVTPPVP-TMPGMCRVTCGHCSDTFLFNTYHN-ALARCPHCRKVSSVGSRFANSRAVMFAIVALVFLITGIAVTIGTYSIASDHGGMYFLYVALFVISGCMLARSAYYFRLKVSAIDGPM-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** **..*: . *. * . . * : * . * .* ****. *.::...*:::***** *.: * .****** *******:***.**************** :********* ***:***.* . * . * ** **** .***:. : : :************:* *:...*.: :: *:: :* .: **: * : *:* :. .::: * *: :: :*:* ", "identical_positions": 109, "similar_positions": 64, "identity": "38.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JW23-1", "uniprot_id": "A0A0G2JW23_RAT", "id": "A0A0G2JW23-1", "name": "NACHT, LRR and PYD domains-containing protein 12", "aln": "MLPATAKDALHRLSTYLEELEAGELKKFKLYLG-IAEELGQDKIPRGRMEMAGPLEMAQLMVAHMGTKEAWLLALSTFERIHRKDLWERGQGEDLVRVTPSNGLCSLESQS-----------TCLSDVSPDAPRKDPQITYKDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPIWAQQKLLETGWEHSRTRGHQASPIQMETLFEPDEERPEPPRTVVLQGAAGMGKSMLTHKVMLDWADGRLFQDQFDYVFYISCRELNRSHTQCSVHDLLSSCWPEHGAPLEDLIRAPDRLLFIIDGFHELHPSFHDVQGPWCHCWEEKRPTELLLGSLIRRLLLPQLSLLITTRPCALEKLHGLLEHPRHVEILGFSEAEREEYFYRYFHNTGQASQVFSFMRDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTSRTTTAVYMFYLLSLMQPKPG-TPTFKVPANQRG-------LVSLAAEGLWNQKILFEEEDLGKHGLDGAEVSTFLNVN--IFQKG--IKCEKFYSFIHLSFQEFFTAMYCALHGRE------------------AVRRALAEYGFSERNFLAHTVRFLFGLLNEEMRCYLERNLGWT-ISPQVKEEALAWIQNKARSEGSTLQHGSLELLSCLYEIQEEDFIQQALSHFQVVVVRNLSTKMEHVVCSFCARYCRGTEVLHLYGSAYSTGAED----------------------------------GPPEPPGAQTQSTHSQERNILPDIYSAYLSA-------------TICTNSNLIELALYRNALGSQGVRLLCQGLRHANCKLQNLRLKRCHISGSACQDLAAAIIA-NRNLIRLDLSGNSIGVLGLELLCEGLQHPMCRLQMIQLRKCLLEAAAGRALASVLSNN-SHLVELDLTGNPLEDLGLKLLCQGLRHPVCRLRTLWLKI--CHLGQASCEDLASTLKMNQSLMELDLGLNDLGDSGALLLCEGLRHPDCKLQTLRLGICRLGSDACAGVASVLQVNTCLRELDLSFNDLGDRGLWLLGEGLRHQTCRLQKLWLDSCGLTSKACEDLSSVLGISQTLNELYLTNNALGDTGVRLLCKRLRHPGCKLRVLWLFGMDLN-KVTHRRMAALRVTKPYLDIGC--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q5R7-1", "uniprot_id": "NAL12_MOUSE", "id": "E9Q5R7-1", "name": "NACHT, LRR and PYD domains-containing protein 12", "aln": "MLPSTARDGLYRLSTYLEELEAGELKKFKLFLG-IAEDLSQDKIPWGRMEKAGPLEMAQLMVAHMGTREAWLLALSTFQRIHRKDLWERGQGEDLVRVTPNNGLCLFESQS-----------ACPLDVSPNAPRKDLQTTYKDYVRRKFQLMEDRNARLGECVNLSNRYTRLLLVKEHSNPIWTQQKFVDVEWERSRTRRHQTSPIQMETLFEPDEERPEPPHTVVLQGAAGMGKSMLAHKVMLDWADGRLFQGRFDYVFYISCRELNRSHTQCSVQDLISSCWPERGISLEDLMQAPDRLLFIIDGFDKLHPSFHDAQGPWCLCWEEKQPTEVLLGSLIRRLLLPQVSLLITTRPCALEKLHGLLEHPRHVEILGFSEEARKEYFYRYFHNTGQASRVLSFLMDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTPRTTTAVYMFYLLSLMQPKPG-TPTFKVPANQRG-------LVSLAAEGLWNQKILFDEQDLGKHGLDGADVSTFLNVN--IFQKG--IKCEKFYSFIHLSFQEFFAAMYCALNGRE------------------AVRRALAEYGFSERNFLALTVHFLFGLLNEEMRCYLERNLGWS-ISPQVKEEVLAWIQNKAGSEGSTLQHGSLELLSCLYEVQEEDFIQQALSHFQVVVVRSISTKMEHMVCSFCARYCRSTEVLHLHGSAYSTGMED----------------------------------DPPEPSGVQTQSTYLQERNMLPDVYSAYLSA-------------AVCTNSNLIELALYRNALGSQGVRLLCQGLRHASCKLQNLRLKRCQISGSACQDLAAAVIA-NRNLIRLDLSDNSIGVPGLELLCEGLQHPRCRLQMIQLRKCLLEAAAGRSLASVLSNN-SYLVELDLTGNPLEDSGLKLLCQGLRHPVCRLRTLWLKI--CHLGQASCEDLASTLKMNQSLLELDLGLNDLGDSGVLLLCEGLSHPDCKLQTLRLGICRLGSVACVGIASVLQVNTCLQELDLSFNDLGDRGLQLLGEGLRHQTCRLQKLWLDNCGLTSKACEDLSSILGISQTLHELYLTNNALGDTGVCLLCKRLRHPGCKLRVLWLFGMDLN-KKTHRRMAALRVTKPYLDIGC--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A523-1", "uniprot_id": "NLRP3_RAT", "id": "D4A523-1", "name": "NACHT, LRR and PYD domains-containing protein 3", "aln": "---MKMMSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCVPIPRGQMEKADHLDLATLMIDFNGEEKAWGMAVWIFAAINRRDLWEKAKKDQPEWNDACTSNLSMVCQEDSLEEEWIGLLGYLSRISICKKKKDYCKIYRRHVRSRFYSIKDRNARLGESVDLNRRYTQLQLVKEHPSKQEREHELLTIG--RTKMWDRPMSSLKLELLFEPEDEHLEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVS-LRAPKSLADLIISCWPDPNPPVCKILCKPSRILFLMDGFDELQGAFDEHIEEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEILFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGG-IEEHLFSAYLPG-------LCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMN--VFQKE--VDCERFYSFSHMTFQEFFAAMYYLLEEEEEGVTVRKGPEGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCK-ISQQVRLELLKWIEVKAKAKKLQRQPSQLELFYCLYEMQEEDFVQSAMGHFPKIEIN-LSTRMDHVVSSFCIKNCHRVKTLSLG--FLHNSPKE----------------------------------EEEEKRGSQPLD---QVQCVFPDPHVACSS------------------------------------------------------RLVNCCLTSSFCRGLFSSLST-NQSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLTHQCCFNISSVLSSS-QKLVELDLSDNALGDFGVRLLCVGLKHLLCNLQKLWLVS--CCLTSACCQDLALVLSSNHSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSLCCSALTSVLKTNQNLTHLYLRSNALGDMGLKLLCEGLLHPDCKLQMLELDNCSLTSHSCWDLSTILTHNQSLRKLNLSNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLN-CETKRTLEALQEEKPELTVVFEISW----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4B8-1", "uniprot_id": "NLRP3_MOUSE", "id": "Q8R4B8-1", "name": "NACHT, LRR and PYD domains-containing protein 3", "aln": "-----MTSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCIPVPRGQMEKADHLDLATLMIDFNGEEKAWAMAVWIFAAINRRDLWEKAKKDQPEWNDTCTSHSSMVCQEDSLEEEWMGLLGYLSRISICKKKKDYCKMYRRHVRSRFYSIKDRNARLGESVDLNSRYTQLQLVKEHPSKQEREHELLTIG--RTKMRDSPMSSLKLELLFEPEDGHSEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVS-LRTPRSLADLIVSCWPDPNPPVCKILRKPSRILFLMDGFDELQGAFDEHIGEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEVLFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGG-IEEHLFSDYLQG-------LCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMN--VFQKE--VDCERFYSFSHMTFQEFFAAMYYLLEEEAEGETVRKGPGGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCK-ISQQVRLELLKWIEVKAKAKKLQWQPSQLELFYCLYEMQEEDFVQSAMDHFPKIEIN-LSTRMDHVVSSFCIKNCHRVKTLSLG--FFHNSPKE----------------------------------EEEERRGGRPLD---QVQCVFPDTHVACSS------------------------------------------------------RLVNCCLTSSFCRGLFSSLST-NRSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLSHQCCFDISSVLSSS-QKLVELDLSDNALGDFGIRLLCVGLKHLLCNLQKLWLVS--CCLTSACCQDLALVLSSNHSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSICCSALTSVLKTNQNFTHLYLRSNALGDTGLRLLCEGLLHPDCKLQMLELDNCSLTSHSCWNLSTILTHNHSLRKLNLGNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLN-RETKRALEALQEEKPELTIVFEISW----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M918-1", "uniprot_id": "F1M918_RAT", "id": "F1M918-1", "name": "", "aln": "------------------------------------------------------------------------------MKTEDEEMEDQLSKEEIVSED---------------------------------KEFD----YRTIIKENFFIIWDKTSLLGESATLN-------------------------------CVTTHKDQKLLEHIFDVNIQTSKSPQTVVLYGAAGIGKTTLLKKAVLEWADGNLYQ-QFTHVFYLSGREIS-QEKEKNFAQLISKHWPSSEGPIEQILCKPSSLLFILDSFDELDFSFEEPEFALCRDWTQKHPVSFLISSLLRKVMLPESYLLVTTRTTAWKRLVPLLQKPHRVKLPGLSRSSRIDYIHHLLKDKTWAMNAVCSIRMNAKLFNMCHVCHVCQMICTFLKEQVEKGGNVEMTCQTSTALFTYYICSLFPRIAGSSVTLPNETLLRS-------LCQAAVEGIWTMKHVLYQQNLRKHELTREDLSLFLEAN--VLQQD--TECENCYTFTHLQVQEYFAALFYLLRENPEEKDHPLEP--------FENVHLLLESNHFHDPHLEQMKCFLFGLLNKDRVQQLEETFNLT-ISRAVREELLVCLEALEKDDSPLSQLRIQDLLHCIYETQDEEFITQALTYFQKIMVK-VDEESKLLIYSYCLKHCHSLQTVRLTARADLRNMLDPTAEICLEDAAVRIIHYWQDLFSVLHTNESLLEMDLYESRLDESLMKILNEEFSHPKCNLQKVMFRAVCFLNSCYDFSFLAFNNTVTHLDLKDTDLGDNGVKTLCEALKYQGCKLRVLRLESCDLNVTHCQNLSKALQS-NRSLVFLNLSTNSLSNDGVKSLCEVLENPNCPLERLALASCGLTKVGCEVLSSALTKT-KRLTHLCLAHNVLEDEGIELLSYTLRHPRCTLQSLVLRC--CYFTPIGSEHLSTALQNNKSLIHLDLGFNKLADSGVKLLCQTLQQPNCNLQELELMGCVLTSEACGDLASVLVNNSNLWNLDLGNNILDDAGLNILCEALRNPNCQIRRLGLENCGLTPGCCQDLLDLLSNNQSVIQMNLMKNSLDYEAIRNLCKVLRSPTCKMEFLALDKKDLFKKKIKKFLVDVRINNPHLVIRPQCPNTESGCWWQYF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6B966-1", "uniprot_id": "NAL14_MOUSE", "id": "Q6B966-1", "name": "NACHT, LRR and PYD domains-containing protein 14", "aln": "------------------------------------------------------------------------------MKTEDDEMEYEASKEETVSED---------------------------------KDFDDGIDYRTVIKENIFTMWYKTSLHGEFATLN-------------------------------CVITPKDQNLLQHIFDEDIQTSEAPQTVVLQGAAGIGKTTLLKKAVLEWADGNLYQ-QFTHVFYLNGKEIS-QVKEKSFAQLISKHWPSSEGPIEQVLSKPSSLLFIIDSFDELDFSFEEPQFALCKDWTQISPVSFLISSLLRKVMLPESYLLVATRSTAWKRLVPLLQKPQRVKLSGLSKNARMDYIHHLLKDKAWATSAIYSLRMNWRLFHMCHVCHMCQMICAVLKGQVEKGGRVEETCKTSTALFTYYICSLFPRIPVGCVTLPNETLLRS-------LCKAAVEGIWTMKHVLYQQNLRKHELTREDILLFLDAK--VLQQD--TEYENCYMFTHLHVQEFFAALFYLLRENLEEQDYPSEP--------FENLYLLLESNHIHDPHLEQMKCFLFGLLNKDRVRQLEETFNLT-ISMEVREELLACLEGLEKDDSSLSQLRFQDLLHCIYETQDQEFITQALMYFQKIIVR-VDEEPQLRIYSFCLKHCHTLKTMRLTARADLKNMLD-TAEMCLEGAAVQVIHYWQDLFSVLHTNESLIEMDLYESRLDESLMKILNEELSHPKCKLQKLIFRAVDFLNGCQDFTFLASNKKVTHLDLKETDLGVNGLKTLCEALKCKGCKLRVLRLASCDLNVARCQKLSNALQT-NRSLVFLNLSLNNLSNDGVKSLCEVLENPNSSLERLALASCGLTKAGCKVLSSALTKS-KRLTHLCLSDNVLEDEGIKLLSHTLKHPQCTLQSLVLRS--CSFTPIGSEHLSTALLHNRSLVHLDLGQNKLADNGVKLLCHSLQQPHCNLQELELMSCVLTSKACGDLASVLVNNSNLWSLDLGHNILDDAGLNILCDALRNPNCHVQRLGLENCGLTPGCCQDLLGILSNNKSVIQMNLMKNALDHESIKNLCKVLRSPTCKMEFLALDKKEILKKKIKKFLVDVRINNPHLVIGPECPNTESGCWWNYF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32TUF4-1", "uniprot_id": "A0AB32TUF4_DANRE", "id": "A0AB32TUF4-1", "name": "", "aln": "-----------------------------------MHHCGNEEVDREEKEKHGAEHSCVSMKSDQSMRNPIAFTDKAVTFDLRSVASSSSHFETHTVQEKTDKG-------------------LQTQIFETEELQRVKDQHKTSMRKKYELLSEGIKVKETGTQLNRIYTQLYIIEGESEGVNEEHEVLQMEK-TARTKHSQHTPIYCNDIFKEEK---EQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQ-DVDFMFVLPFRELNLIRDHQYSLHTLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIK-RLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEED-LSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVDVSDASVYSGICTEIFKEESVIQQRKVYSFIHLSVQEFLAAFYVFYYHVNTTMMGLKTFAS----LQKLLKGAVDDAIESKNGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEG--------------------------------------------------RRRLIPAVSNCTRAL------------------------------------------------------LAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCRLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRIKPGLKKYACFLTLDPNTAHVQIQLS-EGNREARNVKDPQPYPDH-------------PDRFDQQEQVLCRETLTGRCYWEVKWSGSGHIGVAYKAIDRKSGLDSWFGLNENSWSLYCCDTNYTVWYNNESADIIAPSARTNRVGVYLDVSSGSLSFYTVSDANTLTLIHTFNTTFTEPLYTGFGLYPESSVSLCQI-----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :: . : . *. : :*. : : :**: * **:**: :* :*:** *. : . .:* : :*:. . : : : : ::*::*.:.: :: : .*:..*:: :**. : :::*. * ::: : : .:: *::. : :*: : : : * . : *. **.: .. : .: *: :* . :* * :: .:: : . * . * : . : :: : :* : : : : :::: . .. * * *: .**:::*:: : : . * **:*: :. :: : . * . :: :*: *: * ::: : . .. . * . . * * * :. *. : : : * * *:** * : *:. *.: *: * . :: : * * : ::*.*:.. . * .* *: * : *:.** *.. *:.* * :. : * : . .: : . .: . : . *. . .** : : .. : : ..: . : *:. . : .* : ..: : . :.. * . : * : ", "identical_positions": 89, "similar_positions": 229, "identity": "7.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-202", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14197-1", "uniprot_id": "ICT1_HUMAN", "id": "Q14197-1", "name": "Large ribosomal subunit protein mL62", "aln": "MAATRCLRWGLSRAGVWLLPPPARCPRRALHKQKDGTEFKSIYSLDKLYPESQGSDTAWRVPNGAK-QADSDIPLDRLTISYCRSSGPGGQNVNKVNSKAEVRFHLATAEWIAEPVRQKIAITHKNKINRLGELILTSESSRYQFRNLADCLQKIRDMITEASQTPKEPTKEDVKLHRIRIENMNRERLRQKRIHSAVKTSRRVDMD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R035-1", "uniprot_id": "ICT1_MOUSE", "id": "Q8R035-1", "name": "Large ribosomal subunit protein mL62", "aln": "MATAWGLRWGLSRTGTLLLAPPARCARRALHRQVDGTTFQSIYSLDKLYPESKGADTAWKVPEHAK-QASSYIPLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIEEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAEASQVPKEPSKEDARLQRLRIEKMNRERLRQKRLNSALKTSRRMTMD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F0D0-1", "uniprot_id": "E7F0D0_DANRE", "id": "E7F0D0-1", "name": "Large ribosomal subunit protein mL62", "aln": "MAAP----------AVCSFSPLVCACRWRLT----GITALSSGTAGIQHRPGIGFCPARAAARSTQDQQLTHIPVDKLKVSYSRSSGAGGQHVNKVNTKAEVRFHVQTADWLPETLKSQILLKHQSRINKAGELFVRSEISRSQRRNLQECVQKLTALIQEAEQQEAEPSPEDQELWKNRLNKRNLERLKQKKIHSATKRARRPDFD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:. .. :.* . . * * * * : . : . * .* ... :: * : **:*:*.:**.****.***:*****:*******: :*:*: *.::.:* :.*:.:**: ***.: ** ** * *** :*:**: :* **.* **: ** .* : *::: * ***:**:::** * :** :*", "identical_positions": 78, "similar_positions": 61, "identity": "37.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-207", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZWY9-1", "uniprot_id": "H2B1C_MOUSE", "id": "Q6ZWY9-1", "name": "Histone H2B type 1-C/E/G", "aln": "MPEP-AKSAPAPKKGSKKAVTKAQKK--DGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64478-1", "uniprot_id": "H2B1H_MOUSE", "id": "Q64478-1", "name": "Histone H2B type 1-H", "aln": "MPEP-AKSAPAPKKGSKKALTKAQKK--DGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10854-1", "uniprot_id": "H2B1M_MOUSE", "id": "P10854-1", "name": "Histone H2B type 1-M", "aln": "MPEP-TKSAPAPKKGSKKAVTKAQKK--DGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64525-1", "uniprot_id": "H2B2B_MOUSE", "id": "Q64525-1", "name": "Histone H2B type 2-B", "aln": "MPDP-AKSAPAPKKGSKKAVTKVQKK--DGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23527-1", "uniprot_id": "H2B1O_HUMAN", "id": "P23527-1", "name": "Histone H2B type 1-O", "aln": "MPDP-AKSAPAPKKGSKKAVTKAQKK--DGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q16778-1", "uniprot_id": "H2B2E_HUMAN", "id": "Q16778-1", "name": "Histone H2B type 2-E", "aln": "MPEP-AKSAPAPKKGSKKAVTKAQKK--DGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10853-1", "uniprot_id": "H2B1F_MOUSE", "id": "P10853-1", "name": "Histone H2B type 1-F/J/L", "aln": "MPEP-AKSAPAPKKGSKKAVTKAQKK--DGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CGP2-1", "uniprot_id": "H2B1P_MOUSE", "id": "Q8CGP2-1", "name": "Histone H2B type 1-P", "aln": "MPEP-VKSVPAPKKGSKKAVTKAQKK--DGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64524-1", "uniprot_id": "H2B2E_MOUSE", "id": "Q64524-1", "name": "Histone H2B type 2-E", "aln": "MPEL-AKSAPAPKKGSKKAVTKAQKK--DGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIANEASRLAHYNKRSTITSREIQTSVRLLLPGELAKHAVSEGTKAVTKYTSAK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CGP1-1", "uniprot_id": "H2B1K_MOUSE", "id": "Q8CGP1-1", "name": "Histone H2B type 1-K", "aln": "MPEP-AKSAPAPKKGSKKAVTKAQKK--DGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64475-1", "uniprot_id": "H2B1B_MOUSE", "id": "Q64475-1", "name": "Histone H2B type 1-B", "aln": "MPEP-SKSAPAPKKGSKKAISKAQKK--DGKKRKRSRKESYSVYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P33778-1", "uniprot_id": "H2B1B_HUMAN", "id": "P33778-1", "name": "Histone H2B type 1-B", "aln": "MPEP-SKSAPAPKKGSKKAITKAQKK--DGKKRKRSRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZNZ9-1", "uniprot_id": "D3ZNZ9_RAT", "id": "D3ZNZ9-1", "name": "Histone H2B", "aln": "MPEP-SRSTPAPKKGSKKAITKAQKK--DGKKRKRGRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D2U9-1", "uniprot_id": "H2B3A_MOUSE", "id": "Q9D2U9-1", "name": "H2B.U histone 2", "aln": "MPEP-SRSTPAPKKGSKKAITKAQKK--DGKKRKRGRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8CGP0-1", "uniprot_id": "H2B3B_MOUSE", "id": "Q8CGP0-1", "name": "Histone H2B type 3-B", "aln": "MPDP-SKSAPAPKKGSKKAVTKAQKK--DGKKRKRGRKESYSIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1R4A4-1", "uniprot_id": "F1R4A4_DANRE", "id": "F1R4A4-1", "name": "Histone H2B", "aln": "MPEP-AKTAP--KKGSKKAVTKTAGK--SGKKRRRTRKESYAIYVYKVLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q00729-1", "uniprot_id": "H2B1A_RAT", "id": "Q00729-1", "name": "Histone H2B type 1-A", "aln": "MPEVSAKGTTISKKGFKKAVTKTQKK--EGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P02283-1", "uniprot_id": "H2B_DROME", "id": "P02283-1", "name": "Histone H2B", "aln": "MPPK--TSGKAAKKAGK--AQKNITK--TDKKKKRKRKESYAIYIYKVLKQVHPDTGISSKAMSIMNSFVNDIFERIAAEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P02293-1", "uniprot_id": "H2B1_YEAST", "id": "P02293-1", "name": "Histone H2B.1", "aln": "MSAKAEKKPASKAPAEKKPAAKKTSTSTDGKKRSKARKETYSSYIYKVLKQTHPDTGISQKSMSILNSFVNDIFERIATEASKLAAYNKKSTISAREIQTAVRLILPGELAKHAVSEGTRAVTKYSSSTQA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . * * . .:*: : ***:*: *:******.*******.*:*.*:****.******* ***:** ***:***::**:**:***:**************:*****:*:. ", "identical_positions": 74, "similar_positions": 27, "identity": "56.49%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-209", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P38040-1", "uniprot_id": "GBG1_DROME", "id": "P38040-1", "name": "Guanine nucleotide-binding protein subunit gamma-1", "aln": "---MDVMSSSLQQQRVVVEQLRREAAIDRQTISESCAKMMKYITEHEQEDYLLTGFTSQKVNPFREKSSCTVL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "R4GE45-1", "uniprot_id": "R4GE45_DANRE", "id": "R4GE45-1", "name": "Guanine nucleotide-binding protein subunit gamma", "aln": "MSNNNASSSSVAAAQKAVKQLRHEADMDRMKVSQAAKDLINFCVQNAIKDPLLATIS-PKDNPFRPPKSCGLL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. ***: : .*:***:** :** .:*::. .:::: .:: :* **: :: * **** .** :*", "identical_positions": 23, "similar_positions": 27, "identity": "31.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-210", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D9A7-1", "uniprot_id": "PTG3L_MOUSE", "id": "Q9D9A7-1", "name": "Putative protein PTGES3L", "aln": "-------------------------------------------MERQPARTLWYDRPKYVFMEFCVEDSTDVSVLIEDHRVVFSCRNGDGVELYNEIEFYAKVNSKDSQDKRSGRSITCFVRKWKEKVAWPRLTKEDIKPVWLSVDFDNWRDWEGDDEVELAQVEHYAE------------------DDSDS-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PB15-1", "uniprot_id": "PTG3L_HUMAN", "id": "E9PB15-1", "name": "Putative protein PTGES3L", "aln": "MFSLPLNCSPDHIRRGSCWGRPQDLKIAAPAWNSKCHPGAGAAMARQHARTLWYDRPRYVFMEFCVEDSTDVHVLIEDHRIVFSCKNADGVELYNEIEFYAKVNSK---------------------------------PVWLSVDFDNWRDWEGDEEMELAHVEHYAELLKKVSTKRPPPAMDDLDDDSDSADDATSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QBW9-1", "uniprot_id": "F1QBW9_DANRE", "id": "F1QBW9-1", "name": "CS domain-containing protein", "aln": "------------------------------------MPKIVRPENCQPAKTLWYDRKKYVTINFVVQNPKDVQVDVQDKKIILSCKDVDDNNIYNEIEFYDRVLKADSREKVHDRTINVLIRKVKENVAWPRLQKDTAKPAWLLVDFDNWRDWEHEEEEGMAEYEQYVDMLNDVKNKGEPPAMDDLDDLSD--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:****** :** ::* *::..** * ::*:::::**:: *. ::******* :* . *.** ********** ::* :*. *:*.: * ** ", "identical_positions": 47, "similar_positions": 30, "identity": "23.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-215", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M8J5-1", "uniprot_id": "F1M8J5_RAT", "id": "F1M8J5-1", "name": "", "aln": "------------------------MLLLLL--------LLWGIKGVEGGAVALKGYTLNVE-RKVVVQEGLCVLVPCNFSYPKFWQT---DSSP-VYGYWFRKKANTDIDAPVATNNPKRPAQERTQHRFFLPG-DQQKNDCSLNIREIKKKDAGTYFFRLERG-KTKY------NYLWNMMTLDVTALTNT-LRILPETLEAGHPSNLTCSVPWDCEKRAPPVFSWNGTSVSPLS-----------TNTTGSSVLTIIPQPQDHGTNLTCQVTLPGTDVTTRMTIRLNVSYAPKNLTVTVYQGA----------------------------------------------------------------------------------------------------------DSVSTILKNGSSLQISEGQSLRLICSAD---SYPPANLSWSWGNLTLCPPKLSKPGLLELFPMHLKHEGVYTCQAQHALG-SQYISLNLSPQ-----------------------------------------RSAT-----LSEMMMG---------------------------------------------------------TLMDSGVTALLFLSFCIILLAVRSCRR--------KPARTAVVAPHP-----NALKVSVSQSPLVESHADDSSEPLPSTVEAAP-----SSTKEEIHYASLSFHEMKPRNSWGQQG--STTEYSEIRLHK-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91Y57-1", "uniprot_id": "SIG12_MOUSE", "id": "Q91Y57-1", "name": "Sialic acid-binding Ig-like lectin 12", "aln": "----------------------MLLLLLLL--------LLWGIKGVEG-QNPQEVFTLNVE-RKVVVQEGLCVLVPCNFSYLKKRLTDWTDSDP-VHGFWYREGTDRRKDSIVATNNPIRKAVKETRNRFFLLG-DPWRNDCSLNIREIRKKDAGLYFFRLERG-KTKY------NYMWDKMTLVVTALTNTPQILLPETLEAGHPSNLTCSVPWDCGWTAPPIFSWTGTSVSFLS-----------TNTTGSSVLTITPQPQDHGTNLTCQVTLPGTNVSTRMTIRLNVSYAPKNLTVTIYQGA----------------------------------------------------------------------------------------------------------DSVSTILKNGSSLPISEGQSLRLICSTD---SYPPANLSWSWDNLTLCPSKLSKPGLLELFPVHLKHGGVYTCQAQHALG-SQHISLSLSPQ-----------------------------------------SSAT-----LSEMMMG---------------------------------------------------------TFVGSGVTALLFLSVCILLLAVRSYRR--------KPARPAVVAPHP-----DALKVSVSQNPLVESQADDSSEPLPSILEAAP-----SSTEEEIHYATLSFHEMKPMNLWGQQD--TTTEYSEIKFPQRTAWP--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y286-1", "uniprot_id": "SIGL7_HUMAN", "id": "Q9Y286-1", "name": "Sialic acid-binding Ig-like lectin 7", "aln": "----------------------MLLLLLLP--------LLWGRERVEGQKSNRKDYSLTMQ-SSVTVQEGMCVHVRCSFSYPVDSQT---DSDP-VHGYWFRAGNDISWKAPVATNNPAWAVQEETRDRFHLLG-DPQTKNCTLSIRDARMSDAGRYFFRMEKG-NIKW------NYKYDQLSVNVTALTHRPNILIPGTLESGCFQNLTCSVPWACEQGTPPMISWMGTSVSPLH-----------PSTTRSSVLTLIPQPQHHGTSLTCQVTLPGAGVTTNRTIQLNVSYPPQNLTVTVFQGE----------------------------------------------------------------------------------------------------------GTASTALGNSSSLSVLEGQSLRLVCAVD---SNPPARLSWTWRSLTLYPSQPSNPLVLEL-QVHLGDEGEFTCRAQNSLG-SQHVSLNLSLQ-----------------------------------------QEYTGKMRPVSGVLLG---------------------------------------------------------AVGGAGATALVFLSFCVIFIVVRSCRK--------KSARPAADVGDIGMKDANTIRGSASQGNLTESWADDNPRHHG--LAAHS-----SGEEREIQYAPLSFHKGEPQDLSGQEA--TNNEYSEIKIPK-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y336-1", "uniprot_id": "SIGL9_HUMAN", "id": "Q9Y336-1", "name": "Sialic acid-binding Ig-like lectin 9", "aln": "-----------------------MLLLLLP--------LLWGRERAEGQTSK----LLTMQ-SSVTVQEGLCVHVPCSFSYPSHGWI---YPGPVVHGYWFREGANTDQDAPVATNNPARAVWEETRDRFHLLG-DPHTKNCTLSIRDARRSDAGRYFFRMEKG-SIKW------NYKHHRLSVNVTALTHRPNILIPGTLESGCPQNLTCSVPWACEQGTPPMISWIGTSVSPLD-----------PSTTRSSVLTLIPQPQDHGTSLTCQVTFPGASVTTNKTVHLNVSYPPQNLTMTVFQGD----------------------------------------------------------------------------------------------------------GTVSTVLGNGSSLSLPEGQSLRLVCAVDAVDSNPPARLSLSWRGLTLCPSQPSNPGVLELPWVHLRDAAEFTCRAQNPLG-SQQVYLNVSLQ-----------------------------------------SKAT------SGVTQG---------------------------------------------------------VVGGAGATALVFLSFCVIFVVVRSCRK--------KSARPAAGVGDTGIEDANAVRGSASQGPLTEPWAEDSPPDQPPPASARS-----SVGEGELQYASLSFQMVKPWDSRGQEA--TDTEYSEIKIHR-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NYZ4-1", "uniprot_id": "SIGL8_HUMAN", "id": "Q9NYZ4-1", "name": "Sialic acid-binding Ig-like lectin 8", "aln": "---------------------MLLLLLLLP--------LLWGTKGMEGDRQYGDGYLLQVQ-ELVTVQEGLCVHVPCSFSYPQDGWT---DSDP-VHGYWFRAGDRPYQDAPVATNNPDREVQAETQGRFQLLG-DIWSNDCSLSIRDARKRDKGSYFFRLERG-SMKWSYKSQLNYKTKQLSVFVTALTHRPDILILGTLESGHSRNLTCSVPWACKQGTPPMISWIGASVSSPG-----------PTTARSSVLTLTPKPQDHGTSLTCQVTLPGTGVTTTSTVRLDVSYPPWNLTMTVFQGD----------------------------------------------------------------------------------------------------------ATASTALGNGSSLSVLEGQSLRLVCAVN---SNPPARLSWTRGSLTLCPSRSSNPGLLELPRVHVRDEGEFTCRAQNAQG-SQHISLSLSLQ-----------------------------------------NEGTGTSRPVSQVTLA---------------------------------------------------------AVGGAGATALAFLSFCIIFIIVRSCRK--------KSARPAAGVGDTGMEDAKAIRGSASQGPLTESWKDGNPLKKPPPAVAPS-----SGEEGELHYATLSFHKVKPQDPQGQEA--TDSEYSEIKIHKRETAETQACLRNHNPSSKEVRG---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08ET2-1", "uniprot_id": "SIG14_HUMAN", "id": "Q08ET2-1", "name": "Sialic acid-binding Ig-like lectin 14", "aln": "----------------------MLPLLLLP--------LLWG-----GSLQEKPVYELQVQ-KSVTVQEGLCVLVPCSFSYPWRSWY---SSPP-LYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLG-DVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKY------SYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLD-----------PETTRSSELTLTPRPEDHGTNLTCQVKRQGAQVTTERTVQLNVSYAPQNLAISIFFRNG--------------------------------------------------------------------------------------------------------TGTALRILSNGMSVPIQEGQSLFLACTVD---SNPPASLSWFREGKALNPSQTSMSGTLELPNIGAREGGEFTCRVQHPLG-SQHLSFILSVQ------------------------------------------RSSSSCICVTEKQQGSWP---LVLT-------------------------LIRG------------------ALMGAG--FLLTYGLTWIYYTRCGGP-----------QQSRAERPG-------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O15389-1", "uniprot_id": "SIGL5_HUMAN", "id": "O15389-1", "name": "Sialic acid-binding Ig-like lectin 5", "aln": "----------------------MLPLLLLP--------LLWG-----GSLQEKPVYELQVQ-KSVTVQEGLCVLVPCSFSYPWRSWY---SSPP-LYVYWFRDGEIPYYAEVVATNNPDRRVKPETQGRFRLLG-DVQKKNCSLSIGDARMEDTGSYFFRVERGRDVKY------SYQQNKLNLEVTALIEKPDIHFLEPLESGRPTRLSCSLPGSCEAGPPLTFSWTGNALSPLD-----------PETTRSSELTLTPRPEDHGTNLTCQMKRQGAQVTTERTVQLNVSYAPQTITI---FRN----------------------------------------------------------------------------------------------------------GIALEILQNTSYLPVLEGQALRLLCDAP---SNPPAHLSWFQGSPALNATPISNTGILELRRVRSAEEGGFTCRAQHPLG-FLQIFLNLSVYSLPQLLGPSCSWEAEGLHCRCSFRARPAPSLCWRLEEKPLEGNSSQGSFKVNSSSAGPWANSSLILHGGLSSDLKVSCKAWNIYGSQSGSVLLLQGRS-------NLGTGVVPAALGGAGVMALLCICLCLIFFLIVKAR-----------RKQAAGRPEKMDDEDPIMGTITSGSRKKPWPDSPGDQASPPGDAPP------LEEQKELHYASLSFSEMKSREPKDQEAP-STTEYSEIKTSK-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JVW0-1", "uniprot_id": "A0A0G2JVW0_RAT", "id": "A0A0G2JVW0-1", "name": "", "aln": "---------------------MSLLMFLLS--------LLLD-----GSQGQMEKYFLQVQ-RIVKAQEGLCIFVPCSFISPENRWF---NLYP-EYGYWFKEIRRQSLQYPVATNNKDKGLEQGAPGRFQLLG-DLSQKKCSLLIKDVRWEDSTKYFFRIEKG-YEKY------SFK-EAFTLQVEALTQKPDIFIPEILEPGQPVTIVCLFSWNFEQCPAPSFSWMGAAASFQETR---------PHTSHYSVLSFTPGLQHNGTELTCQLDFSRK--STQRTVQLRVAYAPRSLAISIFRDNVSVPELN--RNPSHLEVQQGQSLRLLCTADSQPPATLSWVLEDRVLSWSSPVGSRTLALEMPWVKAGDSGHYTCQAENRLGSQQQTLDLSVLYPPEDLRVTVSQENRTVLEILRNGTSLPVLEGQSLCLVCVTY---SNPPASVSWFGATQTLIPTQSSEPGVLELPLVQREHEGELTCAAQSPLG-TQRISLSLSVHYPPQMSRPSCSWDSEGLHCSCSSRAWPAPSLRWRLGEGLLEGNSSNASFKVTSSSLGPWANSSLSLLQELEPSLWLSCEAWNTHGAQTTSVLLLPDKN--------SSAAFSKGAALGFGITALLALCLVVIIMKTLQKKGT-----QEVTSRPKISRGSTILDYINVVPKTRSPAR--NWKAEPDTPSGISPLDTHSPKPKKKQKDPRFTSPGFPDPRPSSQAPVSENNP-EELHYAALNFPRLR-LRETQNPQDTYSDYAEVRVH--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80ZE3-1", "uniprot_id": "SIG10_MOUSE", "id": "Q80ZE3-1", "name": "Sialic acid-binding Ig-like lectin 10", "aln": "---------------------MSLLLFLLS--------FLLD-----GPQGQMESYFLQVQ-RIVKAQEGLCIFVPCSFSSPEGKWL---NRSP-LYGYWFKGIRKPSLSFPVATNNKDKVLEWEARGRFQLLG-DISKKNCSLLIKDVQWGDSTNYFFRMERG-FERF------SFK-EEFRLQVEALTQKPDIFIPEVLEPGEPVTVVCLFSWTFNQCPAPSFSWMGDAVSFQESR---------PHTSNYSVLSFIPGLQHHDTELTCQLDFSRM--STQRTVRLRVAYAPRSLAISIFHDNVSVPDLH--ENPSHLEVQQGQSLRLLCTADSQPPATLSWVLEDQVLSWSSPVGSRTLALELPWVKAGDSGHYTCQAENRLGSQQHTLDLSVLYPPQDLRVTVSQANRTVLEILRNAISLPVLEGQSLCLVCVTY---SNPPANVSWAWVTQTLIPIQSSEPGVLELPLVQREHEGEFTCAAQNPLG-AQRISLSLSVHYPPQMSSPSCSWEAKGLHCNCSSRAWPAPSLRWRLGEGLLEGNSSNASFTVTFSSLGPWVNSSLSLLQELGPSLWLSCESWNTHGAQTTSVLLLPDKD--------SATAFSKGAVLGFGITALLALCLIVVIVKTLQKKGT-----QEEPSRPKLSRGSTILDYINVVPKTRSLAR--NWKAEPDAPSRSSPLDTHFPKPKKKQKDPHFTYPGCPDPTSSSQVPVSENNP-EELHYAALNFSRLR-LQETQDPQDTYSDYTEVRVH--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96LC7-1", "uniprot_id": "SIG10_HUMAN", "id": "Q96LC7-1", "name": "Sialic acid-binding Ig-like lectin 10", "aln": "----------------------MLLPLLLS--------SLLG-----GSQAMDGRFWIRVQ-ESVMVPEGLCISVPCSFSYPRQDWT---GSTP-AYGYWFKAVTETTKGAPVATNHQSREVEMSTRGRFQLTG-DPAKGNCSLVIRDAQMQDESQYFFRVERGSYVRY------NFMNDGFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFEECPPPSFSWTGAALSSQGTK---------PTTSHFSVLSFTPRPQDHNTDLTCHVDFSRKGVSAQRTVRLRVAYAPRDLVISISRDNTPALEPQPQGNVPYLEAQKGQFLRLLCAADSQPPATLSWVLQNRVLSSSHPWGPRPLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLCLVCVTH---SSPPARLSWTQRGQVLSPSQPSDPGVLELPRVQVEHEGEFTCHARHPLG-SQHVSLSLSVHYSPKLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQDSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCEAWNVHGAQSGSILQLPDKKG------LISTAFSNGAFLGIGITALLFLCLALIIMKILPKRRT-----QTETPRPRFSRHSTILDYINVVPTAGPLAQKRNQKATPNSPRTPLPPGAPSPESKKNQKK-QYQLPSFPEPKSSTQAPESQESQ-EELHYATLNFPGVRPRPEARMPKGTQADYAEVKFQ--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96RL6-1", "uniprot_id": "SIG11_HUMAN", "id": "Q96RL6-1", "name": "Sialic acid-binding Ig-like lectin 11", "aln": "---------MVPGQAQPQSPEMLLLPLLLP--------VLGA-----GSLNKDPSYSLQVQ-RQVPVPEGLCVIVSCNLSYPRDGWD---ESTA-AYGYWFKGRTSPKTGAPVATNNQSREVEMSTRDRFQLTG-DPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRH------SFLSNAFFLKVTALTKKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTR---------PSTSHFSVLSFTPSPQDHDTDLTCHVDFSRKGVSAQRTVRLRVAYAPKDLIISISHDNTSALELQ--GNVIYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELRGVRAGDSGRYTCRAENRLGSQQQALDLSVQYPPENLRVMVSQANRTVLENLGNGTSLPVLEGQSLRLVCVTH---SSPPARLSWTRWGQTVGPSQPSDPGVLELPPIQMEHEGEFTCHAQHPLG-SQHVSLSLSVHYPPQLLGPSCSWEAEGLHCSCSSQASPAPSLRWWLGEELLEGNSSQGSFEVTPSSAGPWANSSLSLHGGLSSGLRLRCKAWNVHGAQSGSVFQLLPGKL------EHGGGLGLGAALGAGVAALLAFCSCLVVFRVKICR---------KEARKRAAAEQ------DVPSTLGPISQGHQHECSAGSSQDHPPPGAATYTPGKGEEQ-ELHYASLSFQGLRLWEPADQEAP-STTEYSEIKIHTGQPLRGPGFGLQLEREMSGMVPK--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0M7S7-1", "uniprot_id": "A0ABK0M7S7_RAT", "id": "A0ABK0M7S7-1", "name": "", "aln": "MRQFRSGGRLFLADFGSHDATQEKWKCLFSKGLDIADNLRVESSFLLCGSLAVENYELSLT-ESVTVQEGLCVFVPCQVKYPASGGS--------VFGYWFQDGANTNLNSPVATNDPHRPVQQETQGRFYLVG-GIDTKNCSLDIRDARKSDTGKYFFRLDGS--VKY------SFRNRMLSVHVTALTKTPNLQVTSTLVSGTSTRVICSVLWACEQGTPPIFSWMSSALTSLG-----------RRTILSSELNLTPRPQDNGTNLICQVTFPGAGVTVERTQQLSVTYAPQKLTIRVSWGD----------------------------------------------------------------------------------------------------------GTETKVLQSGASLQIQEGESLRLVCVAD---SNPSAMLSWKR--QTQKNFRLSKGDELQLPRVELEDQGKYICQAKNSLG-TQTASVSLSIRSLLQLLAPSCSWDSEGLHCSCSSRAWPAPSLGWRLGEGLLEGNSSNASFTVMSSSAGPWVNSSLSLSVEFSTDHRLSCEAWNDYGVQRATIVLVPGQGVSQADKSETSGGAVQGAIWGAGLMALLAVSFCLIFFIVKFLRKKSALEVAAMEGNHLAKNLVSTINSASMISSNIPLRYPIQDHLNESESQTQKEEPPLATAPDIPKDEPELHYASLSFQGPRPQQPKNTET--IKSVYTEIKIHKR------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q920G3-1", "uniprot_id": "SIGL5_MOUSE", "id": "Q920G3-1", "name": "Sialic acid-binding Ig-like lectin 5", "aln": "----------------------MRWAWLLP--------------LLWAGCLATDGYSLSVT-GSVTVQEGLCVFVACQVQYPNSKGP--------VFGYWFREGANIFSGSPVATNDPQRSVLKEAQGRFYLMG-KENSHNCSLDIRDAQKIDTGTYFFRLDGS--VKY------SFQKSMLSVLVIALTEVPNIQVTSTLVSGNSTKLLCSVPWACEQGTPPIFSWMSSALTSLG-----------HRTTLSSELNLTPRPQDNGTNLTCQVNLPGTGVTVERTQQLSVIYAPQKMTIRVSWGD----------------------------------------------------------------------------------------------------------DTGTKVLQSGASLQIQEGESLSLVCMAD---SNPPAVLSWER--PTQKPFQLSTPAELQLPRAELEDQGKYICQAQNSQG-AQTASVSLSIRSLLQLLGPSCSFEGQGLHCSCSSRAWPAPSLRWRLGEGVLEGNSSNGSFTVKSSSAGQWANSSLILSMEFSSNHRLSCEAWSDNRVQRATILLVSGPKVSQAGKSETSRGTVLGAIWGAGLMALLAVCLCLIFFTVKVLRKKSALKVAATKGNHLAKNPASTINSASITSSNIALGYPIQGHLNEPGSQTQKEQPPLATVPDTQKDEPELHYASLSFQGPMPPKPQNTEA--MKSVYTEIKIHKC------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63994-1", "uniprot_id": "CD33_MOUSE", "id": "Q63994-1", "name": "Myeloid cell surface antigen CD33", "aln": "-------------------MLWPLPLFLLC----------------AGSLAQDLEFQLVAP-ESVTVEEGLCVHVPCSVFYPSIKLT----LGP-VTGSWLRKGVSLHEDSPVATSDPRQLVQKATQGRFQLLG-DPQKHDCSLFIRDAQKNDTGMYFFRVVREPFVRY------SYKKSQLSLHVTSLSRTPDIIIPGTLEAGYPSNLTCSVPWACEQGTPPTFSWMSTALTSLS-----------SRTTDSSVLTFTPQPQDHGTKLTCLVTFSGAGVTVERTIQLNVTRKSGQMRELVLVAVG---------------------------------------------------------------------------------------------------------EATVKLLILG----------LCLVFLIVMFCRRKTTKLSVHMGCENPIKRQEAITSYNHCLSPTASDAVTPGCSIHRLISRTPRCTAILRIQDP--------------------------------------------------------------------------------------------------------------------YRRTHLRNRAVSTLRFPWISWEG-----------SLRSTQRSKCTKLCSPVKNLCPLWLPVDNSCIP-----------------LIPEWVMLLCVSLTLS---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32T5V7-1", "uniprot_id": "A0AB32T5V7_DANRE", "id": "A0AB32T5V7-1", "name": "", "aln": "----------------------MKIISLCT-------IIFMLVFNVLCEENADNGWNISFSPREVTAVKGLCAHISCTFTYPVAENP-------IQSVIWQSCVAKDKCNLIFQNNVEKNKLKKNELGHIKMLEPDLSKNNCSIILKDIKENEK-EYTFRIKAK-------------QQYTFNPTVKISIKDEPTLVVPPLSEKVEVNLTCSAPFPCPETPPVITWWIKTKEENYIKLDNNKITQVHSEHVYYSYLTLIPTSDQHDGTVGCDVRYGNKKINTNNTLEVKYVQALQIVGEN----------------------------------------------------------------------------------------------------------------------------TLMEGDTLNLTCTFR--SHPPASNPVWRFNGNTDNLNTQTSAGTLMIANVGKEHAGIYVCEMTYMNK-TLNASITINITEVN-ILGENRLKKGDTLNLTCSFKNHPQSSSNPVWSFNGDADKLKNQASAANLIIDNVTKEHAGIYACEMTYMKKTLNASITVDITGVLDFLLSIPN--------------IFTFVAGMAFSALIFSVILCCWVCCHRGKKQ-----KVPTANPDAEINLETVQTDVAQNGTTEQTPLHEQPDGETPKTPATPTDGAEEDEALGTEAREVDYASIDYSLLKDKPPEEAETEPTDTDYAEIKKDRTKDWKDTEDPQDGDEQVETFDQKEMGAEEELYSQVPQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * . :*:* : * . * . .. :: : .*:: : : : : * **: : * . . * : * .. * * *.: * :.:. : * : .. * .: : * * .: : . * : * ", "identical_positions": 23, "similar_positions": 44, "identity": "2.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-216", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZS24-1", "uniprot_id": "D3ZS24_RAT", "id": "D3ZS24-1", "name": "", "aln": "--------MDKEGRSEVTAGLLPIVVISVQVLSKVGDSGLLVAECPPGFQVREAIWRSLWPSEELLATFFRGSLETLYHSRFLGRVQLYDNLSLELGPLRTGDSGNFSVLMVDTGGQTWTQTLHLKVYDAVPKPEVQVFTAATEEAQPLNTCQVFLSC--WAPNISDITYSWRREGTMDFNG------ELRSLFSNGQ-----VLSVSLGLGDKDVAFTCIASNP--------------VSWDMTTVTP-------------WESCHHEAASSGK------------------------------------------------ASYKDVLLVVMPITLFLILAGLFG---AWHHGLCSAGKR-----------------------KDACTDRALPETESAVA-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AB32TTY9-1", "uniprot_id": "A0AB32TTY9_DANRE", "id": "A0AB32TTY9-1", "name": "", "aln": "MVCPALLLQSFIWFSLMSTGVQYEVSHIVSSMCVVRQSTVLIPCKYDGYGFGKQVSSAEWLHEKAAKQKLSVSQDSAFAGR-VEFMTDSGNCSLVLRDVRVSDAGIFSFMLTDDSGHNWTNTQGVRLEVTDVEVEVKTQSDVVMEGD-----WIFFSCGSCIPSMTVPTYTWRKDGHLHSQHYGNNMLDVESVMLEDGGLYLCIISGHEGLNSTQVNITVRPGGPPKSVSVSVSGSAVIVSGDSVTLSCSSDSNPPAVNFTWLKETQSSAVGSGQSFSALDSGRYYCEAENKYGSQRSESVSVTNKDEESSSSWIMFTAGITAAAFVASVILIVSIWLLIRRKRVTRSEEKNHRGRCKTVESSEDPYMTLDPKSRCSEYDTLDNIKRSWVNADSPEDEDSAYYNIKE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * :::*: * *. :. * :* :*:. *: . : : : * *: : * :: : .* : : .* ** * :*..*:* **.::.* .*:.**:* ::: : : **:. : .. *.: :*:** *.:: **:**::* :. : ::.*:: :. ::* **...:* :* ...* ** * .*:: :. : .*..**: *:: :::::.* *:: : *:* *.: : * : .: ** *.:. ", "identical_positions": 62, "similar_positions": 109, "identity": "15.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-220", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A4E5-1", "uniprot_id": "D4A4E5_RAT", "id": "D4A4E5-1", "name": "", "aln": "MEEKTQIKTFLGSKLPKYGMKSVRSTLQPMSNGATVTLLGTSKSSNVKSYIKNNGSDCSLSHSFNWRKTNKYQLGSQNTAELNNIQITHDKLIDTEQHAPAPGTLDGNGIEGGLNSTSLFTSKLARPSAMFVSSAEELSQKSFSGPSNLGKFTKGTLLGRTSYSSVS-AKSHLNTFYGNRPPGNMQKPRMNSCASRSSSGESLAQSPDNAKSITCEKMVRSQSFSHSIQNAFLPPSSITRSHSFNRAVDLTKPYQNQQLPVRVPLR-----SGMLTRSARQSEVLNGNEHLGFGFNRPYAAGGKKLALSSGPGVSSTLVYRMGHPSLLKSSRPPFSGSMTVDSNKNPSADMCVEEEGVVSAKDSSTGKDQELIENESYRRDND--QTMKHDSKIRYLSDDVDDISLSSLSSSDKNDLSEDFSDDFIDLEDSNRTRITP------EDITLKEEKHENGPSKDVFDSPKESEQIFSKADEWIDISVSDRSECTKHMSGNNLISPDTDYRAGSSFELSPSDSSDGTYMWDEEGLEPIG-SVHPVGSYESSEMNSIDILN---NLESCDLEDDDLMLDVDLPEDAPLENVDCDNMNRFDRTDRNVRQSQDGFWKRPSQRWSGQDHYHLSHPDHYHHHGKSDLSRGSPYRESPLGHFESYGG----------TPFFQAQKMFVDVPDNTVILDEMTLRHMVQDCTAVKTQLLKLKRLLHQHDGSGSLHDVQLS------------------LPSSPEPEDGDQIYT--NEDLLNEIKQLKEELKKKD--------------------------------------------------------------EKIQLLEHQLATRCNCHQKSKEDR---------CAYADKFTQTPWRRSPGGYSAPS-----------------FSPWQGSFQGMPRTVPPHRRQT-----------------------------------------------SSTTASQQPSQIYRPRPG--------KINKVTTYRGPQ--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UHI0-1", "uniprot_id": "CCSE2_MOUSE", "id": "Q3UHI0-1", "name": "Serine-rich coiled-coil domain-containing protein 2", "aln": "MEEKTQIKTFLGSKLPKYGMKSVRSTLQPMPNGATVTLLGTSKSSNVKSYIKNNGSDCSLSHSFNWRKTNKYQLGSQNTAELNNIQSTHDKLIEPEQHAPAPGTLDGHGIKGGLKSASLFTSKLARPSTMFVSSAEELSQKSFSGPSNLGKFTKGTLLGRTSYSSVN-AKSHLNAFYGNRSSGNVQKPRVNSCASRSSSGESLAQSPDNAKSITCEKMVRSQSFSHSIQNVFLPPSSITRSHSFNRAVDLTKPYQNQQLPVRVPLR-----SGMLTRSSLQSEVLNGNEHVGFGFNRPYAAAGKKLALSNGPAVSSTLVYRMAHPPLLKSSRPPFSGPMTVDSNKNPPADMCVEEEGMVSAQDSSPGKDQELIENESYRRDND--QTGKNESKVRYLSDDVDDISLSSLSSSDKNDLSEDFSDDFIDLEDSNRTRITP------EEMTLKEEKHESRPSKDIFDSPKESEQAFSKAEEWIDISVSDRSECTKHTSGNNLISPDTDYRAGSSFELSPSDSSDGTYMWDEEGLEPIG-SVHPVGSYESSEMNSIDILN---NLESCDLEDDDLMLDVDLPEDAPLENVECDNMNRFDRTDRNVRQSQDGFWKRPPQRWSGQDHYHLSHPGHYHHHGQSDLSRGSPYRESPLGHFESYGG----------TPFFQAQKMFVDVPDNTVILDEMTLRHMVQDCTAVKTQLLKLKRLLHQHDGSGSLHDVQLS------------------LPSSPEPEDGDQIYK--NEDLLNEITQLKEEIKKKD--------------------------------------------------------------EKIQLLEQQLATRCNCQQKSKEEK---------CTYADKYTQTPWRRIPGGYCAPS-----------------FSPWQGSFQGMPRTVPPHRRQT-----------------------------------------------SSTTAFQQPSQIYRPRPG--------KTNKATTYRGPQ--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H7U1-1", "uniprot_id": "CCSE2_HUMAN", "id": "Q9H7U1-1", "name": "Serine-rich coiled-coil domain-containing protein 2", "aln": "MEEKTQIKTFLGSKLPKYGTKSVRSTLQPMPNGTPVNLLGTSKNSNVKSYIKNNGSDCPSSHSFNWRKANKYQLCAQGVEEPNNTQNSHDKIIDPEKRVPTQGMFDKNGIKGGLKSVSLFTSKLAKPSTMFVSSTEELNQKSFSGPSNLGKFTKGTLLGRTSYSSINTPKSQLNGFYGNRSAGSMQRPRANSCATRSSSGESLAQSPDSSKSINCEKMVRSQSFSHSIQNSFLPPSSITRSHSFNRAVDLTKPYQNQQLSIRVPLR-----SSMLTRNSRQPEVLNGNEHLGYGFNRPYAAGGKKLALPNGPGVTSTLGYRMVHPSLLKSSRSPFSGTMTVDGNKNSPADTCVEEDATVLAKDRAANKDQELIENESYRTKNN--QTMKHDAKMRYLSDDVDDISLSSLSSSDKNDLSEDFSDDFIDIEDSNRTRITP------EEMSLKEEKHENGPPQDMFDSPKENEKAFSKTDEWIDISVSDRSECTKHTSGNNLVSPDTDYRAGSSFELSPSDSSDGTYMWDEEGLEPIG-NVHPVGSYESSEMNSIDILN---NLESCDLEDDDLMLDVDLPEDAPLENVECDNMNRFDRPDRNVRQPQEGFWKRPPQRWSGQEHYHLSHPDHYHHHGKSDLSRGSPYRESPLGHFESYGG----------MPFFQAQKMFVDVPENTVILDEMTLRHMVQDCTAVKTQLLKLKRLLHQHDGSGSLHDIQLS------------------LPSSPEPEDGDKVYK--NEDLLNEIKQLKDEIKKKD--------------------------------------------------------------EKIQLLELQLATQHICHQKCKEEK---------CTYADKYTQTPWRRIPGGYSAPS-----------------FSPWQGSFQGIPRTVPPHRRQT-----------------------------------------------SSTTAFQQPSQTHRSHPG--------KTNKATTYRGPQ--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QJ31-1", "uniprot_id": "A0A8M9QJ31_DANRE", "id": "A0A8M9QJ31-1", "name": "", "aln": "MEKKALKQLNMVSRLPKFSSRSSGTTTSPLPQGSGLPVP----SYECKGGPVGRQNGLTQVRSLNWRKCEEETG--NNVQCSRSLDEETSATIDSDSPLMVTKKLSPAAVVKCKSAVSTAQCRSIPQPTKTVSRMTTPKRLSTGNTIYNG---MGTLNGASSG--------------NERSSG----SGLGHVSQQKSLQSKLSLSSDRIKSTSKESIERSQSFTYFKRGASHTDPPMTRSFSFNKATDLANKLPRPLAPSPVPRSPLNQPNPVLSKGKVDKFGFTKPSLTASGNILPVATIKKSLLPSFSGNKTSVLSYKLTRPSLNKHPRPVLPAPVQKEAELSEDVQTLTLSAETSSDLTNNTDSTETTPTENEITPNMTPIEVKEFEVSVGSSLEIFEDMSLSSSSSVEHNDS-EEYMDDFDNLGNGGETLFLPVHKDGLDHLGLCEDENGLVTKCNEDSSMTNLHAFLSETVDWEGMGLTGGKDRFEHDSS----SPVGDFPHGSSLDLSPSDSSGGTYMWDEEGMEALGGSGHPCGSFG-SDLNSMDILNKLENVESCDLEDDDLMLDLDLSVDASFH-SDTDEMSSYEWSEKEGRPTQRRRWQQHRGMCENRTGLLQSFDGFRGHGLERSRSDHVTLDDLTLNLVAQDCSSVKEQLLQLMTLLQMETECSVEETSEALTPQSTDQSLLDEKVALLLKEIEELRNELRSKDRMIAELSQQLSSPVEDIQCHCLDGLDGNKLSLEHQDKDTQTLWKPHNLQILQTPRFIPNKLDDHDGLSRPTCKDASCNSLDANPGNHPLTPQPSSSDLQNPIAAASTPNCIAPTVFISADSTAASSSKTFQSSEPAELGLTSSRLKINEPANLPASASFCCKLENGTQKLPFKRSSFSSPQPPSYIKRASTLIKPQEVQRVSVFTGALGRLGATGPPRTRHQPLSAPGLHYINPSQQTSMHTTNLETKCNRQNQEDRQSLFLRKIESSLPRSHASLQPKHSRLPKPQSYSAQPIPAAQKGQTITSPDIPSHMLSQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*: : : *:***:. :* :* .*:.:*: : : . : *. .. .. . :*:**** :: :.. .. : . *:.:. . :. .: .:.* .: .: ** .: * ... * *** * :* .:*..* . . : :.* ..*: *.* ** . *.: *****:: :. . ..:***.***:*.**:: . . ** . :*::. : :. . . * * *: *.* . . :*.* *:: :*.* * .*. :...: :.: . .: . . ... : ::. . :. : : .: : .:*:**** ** ::** *:: *** :: :...* : * :.: * *::: . : .* .: . :*:: :* .:.::. .: :* *. ** *: ***::*******.*********:*.:* . ** **: *::**:**** *:*************:**. **.:. : *:*. :: .::: * .* *:: ..: *. .. * : . * . : .*. . . . : : *: ..::: :. : :. : : .:: :*:. *:.:* : . *** *. . : :* : ::. * ::*: : :::..:* :.:* * .: * :* * : : *::* . . *. .* : *:: : * **: *: . : * **.: .:* :* * .*: ", "identical_positions": 183, "similar_positions": 296, "identity": "17.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-221", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q810W7-1", "uniprot_id": "MAST1_RAT", "id": "Q810W7-1", "name": "Microtubule-associated serine/threonine-protein kinase 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDSLWTALSNFSMPSFPGGSMFRRTKSCRTSNRKSLILTSTSPTLPR--PHSPLPGH-------------------------------------------------------------LGSSPLDSPRNFSPN------TPAHFSFASSRR--------ADGRRWSLASLPSSGYGTNTPSSTVSSSCSSQERLHQLPY--QPTVDELHFLSKHFG--------------------------------------------------------------------------STESITDEDGGRRSPAVRPRSRSLSPGRSPSSYDNEIVMMNHVYKERFPKATAQMEEKLRDFARAYEPDSVLPLADG--VLSFIHHQIIELARDCLTKSRDGLITTVYFYELQENLEKLLQDAYERSESLEVAFVTQLVKKLLIIISRPARLLECLEFNPEEFYHLLEAAEGHAKEGHLVKTDIPRYIIRQLGLTRDPFPDVVRLE---------------------------------------------EQDSG-GSNTPEQ-----------------------------------------------DDTSEGRSSTSKAKKP-PGESDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPEG-DEALPTDAQLLISSLLQTNPLVRLGAG-GAFEVKQHSFFRDLDWTGLLRQKAEFIPHLESEDDTSYFDTRSDRYHHVNSYDEDDTTEEEPVEIRQFSSCSPRFSKVYS--------------------SMEQLSQHEPKTPVSASGASKRDPNAKGPEEKVAGKREGLGG---------------LTLREKTWRGGSPEIKRFSASEASFLEGEAS-PPLGARRRFSALLEPSRFTAPQEDEDEAR-----------LRRPPRPSSDPPSSLDTRVPKEAAQGEGTSTPGEPEATERS-HPGDFCPPSKD-----------------GDPSGPRATNDLVLRRAR------HQQLSGDLSVEKRPSRTGGK--VIKSASATALSVMIPAVDPHGGSPLASPMSPR---SLSSNPSSRDSSPSRDYSPAVSGLRSPITIQRSGKKYGFTLRAIRVYMGDSDVYSVHHIVWHVEEGGPAQEAGLCAGDLITHVNGEPVHGMVHPEVVELILKSGNKVAVTTTPFENTSIRIGPARRSSYKAKMARR---NKRPSAKDGQESKKRSSLFRKITKQSNLLHTSRSLSSLNRSLSSSDSLPGSPTHGLPARSPTHSYRSTPDSAYLGASSQSSSPASSTPNSPASSASHHIRPSTLHGLSPKLHRQYRSARCKSAGNIPLSPLAHTPSPTQASPPPLPGHTVGSSHTTQSFPAKLHSSPPIVRPRPKSAEPPRSPLLKRVQSAEKLGASLG--ADKKG---ALRKHSLEVGHPDFRKD-FHGELALHSLAESDGE---TPPIEGPGATR----------QVAMRRLGRQESPLS---LGADPLLPDGVQRPMASGKE-DSAGGTEACTPPRATTPGSRTLERDLGCTRHQSVQTE--------------------------------------------------------DGPGGVARALAKAALSPVQ-------------------EHETGRRSSSGEAG-TPPVPIVVEPARPGVKTQTPQPLGTDS---------KGLKEP----------VAQIP---LVPDAPRVRERWVLEEVEERTTLSGPRSKPASPKLSP-------DPQTPTVAPTKN-VPRSAAPPVPPAS-------LMVPG------------------TKPEAGSNSRCP--AEGVASAGLTKTGAPSPASLGP------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R1L5-1", "uniprot_id": "MAST1_MOUSE", "id": "Q9R1L5-1", "name": "Microtubule-associated serine/threonine-protein kinase 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDSLWTALSNFSMPSFPGGSMFRRTKSCRTSNRKSLILTSTSPTLPR--PHSPLPGH-------------------------------------------------------------LGSSPLDSPRNFSPN------TPAHFSFASSRR--------ADGRRWSLASLPSSGYGTNTPSSTVSSSCSSQERLHQLPY--QPTVDELHFLSKHFG--------------------------------------------------------------------------STESITDEDGGRRSPAVRPRSRSLSPGRSPSSYDNEIVMMNHVYKERFPKATAQMEEKLRDFARAYEPDSVLPLADG--VLSFIHHQIIELARDCLTKSRDGLITTVYFYELQENLEKLLQDAYERSESLEVAFVTQLVKKLLIIISRPARLLECLEFNPEEFYHLLEAAEGHAKEGHLVKTDIPRYIIRQLGLTRDPFPDVVRLE---------------------------------------------EQDSG-GSNTPEQ-----------------------------------------------DDTSEGRSSTSKAKKP-PGESDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPEG-DEALPTDAQLLISSLLQTNPLVRLGAG-GAFEVKQHSFFRDLDWTGLLRQKAEFIPHLESEDDTSYFDTRSDRYHHVNSYDEDDTTEEEPVEIRQFSSCSPRFSKVYS--------------------SMEQLSQHEPKTPVSASGASKRDPSAKGPEEKVAGKREGLGG---------------LTLREKTWRGGSPEIKRFSASEASFLEGEAS-PPLGARRRFSALLEPSRFTAPQEDEDEAR-----------LRRPPRPSSDPPSSLDTRVPKEAVQGEGTSTPGEPEATERS-HPGDLGPPSKD-----------------GDPSGPRATNDLVLRRAR------HQQLSGDLAVEKRPSRTGGK--VIKSASATALSVMIPAVDPHGGSPLASPMSPR---SLSSNPSSRDSSPSRDYSPAVSGLRSPITIQRSGKKYGFTLRAIRVYMGDSDVYSVHHIVWHVEEGGPAQEAGLCAGDLITHVNGEPVHGMVHPEVVELILKSGNKVAVTTTPFENTSIRIGPARRSSYKAKMARR---NKRPSAKDGQESKKRSSLFRKITKQSNLLHTSRSLSSLNRSLSSSDSLPGSPTHGLPARSPTHSYRSTPDSAYLGASSQSSSPASSTPNSPASSASHHIRPSTLHGLSPKLHRQYRSARCKSAGNIPLSPLAHTPSPTQASPPPLPGHTVGSSHTTQSFPAKLHSSPPVVRPRPKSAEPPRSPLLKRVQSAEKLGASLG--ADKKG---ALRKHSLEVGHPDFRKD-FHGELALHSLAESDGE---TPPIEGPGATR----------QVAVRRLGRQESPLS---LGADPLLPDGVQRPMASSKE-DSAGGTEACTPPRATTPGSRTLERDSGCTRHQSVQTE--------------------------------------------------------DGPGGVARALAKAALSPVQ-------------------EHETGRRSSSGEAG-TPPVPIVVEPARPGVKTQAPQPLGTDS---------KGLKEP----------VAQMP---LMPDAPRGRERWVLEEVEERTTLSGLRSKPASPKLSP-------DPQTPTLVPTKN-VPRSAAPSVPPAS-------LMVPG------------------TKPEAGLNSRCP--AEAVTPAGLTKTGAPSPASLGP------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2H9-1", "uniprot_id": "MAST1_HUMAN", "id": "Q9Y2H9-1", "name": "Microtubule-associated serine/threonine-protein kinase 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDSLWTALSNFSMPSFPGGSMFRRTKSCRTSNRKSLILTSTSPTLPR--PHSPLPGH-------------------------------------------------------------LGSSPLDSPRNFSPN------TPAHFSFASSRR--------ADGRRWSLASLPSSGYGTNTPSSTVSSSCSSQERLHQLPY--QPTVDELHFLSKHFG--------------------------------------------------------------------------STESITDEDGGRRSPAVRPRSRSLSPGRSPSSYDNEIVMMNHVYKERFPKATAQMEEKLRDFTRAYEPDSVLPLADG--VLSFIHHQIIELARDCLTKSRDGLITTVYFYELQENLEKLLQDAYERSESLEVAFVTQLVKKLLIIISRPARLLECLEFNPEEFYHLLEAAEGHAKEGHLVKTDIPRYIIRQLGLTRDPFPDVVHLE---------------------------------------------EQDSG-GSNTPEQ-----------------------------------------------DDLSEGRS--SKAKKP-PGENDFDTIKLISNGAYGAVYLVRHRDTRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVEMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMSLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVISDDILWPEG-DEALPTEAQLLISSLLQTNPLVRLGAG-GAFEVKQHSFFRDLDWTGLLRQKAEFIPHLESEDDTSYFDTRSDRYHHVNSYDEDDTTEEEPVEIRQFSSCSPRFSKVYS--------------------SMEQLSQHEPKTPVAAAGSSKREPSTKGPEEKVAGKREGLGG---------------LTLREKTWRGGSPEIKRFSASEASFLEGEAS-PPLGARRRFSALLEPSRFSAPQEDEDEAR-----------LRRPPRPSSDPAGSLDARAPKEETQGEGTSSAGDSEATDRP-RPGDLCPPSKD-----------------GDASGPRATNDLVLRRAR------HQQMSGDVAVEKRPSRTGGK--VIKSASATALSVMIPAVDPHGSSPLASPMSPR---SLSSNPSSRDSSPSRDYSPAVSGLRSPITIQRSGKKYGFTLRAIRVYMGDTDVYSVHHIVWHVEEGGPAQEAGLCAGDLITHVNGEPVHGMVHPEVVELILKSGNKVAVTTTPFENTSIRIGPARRSSYKAKMARR---NKRPSAKEGQESKKRSSLFRKITKQSNLLHTSRSLSSLNRSLSSSDSLPGSPTHGLPARSPTHSYRSTPDSAYLGASSQSSSPASSTPNSPASSASHHIRPSTLHGLSPKLHRQYRSARCKSAGNIPLSPLAHTPSPTQASPPPLPGHTVGSSHTTQSFPAKLHSSPPVVRPRPKSAEPPRSPLLKRVQSAEKLGASLS--ADKKG---ALRKHSLEVGHPDFRKD-FHGELALHSLAESDGE---TPPVEGLGAPR----------QVAVRRLGRQESPLS---LGADPLLPEGASRPPVSSKEKESPGGAEACTPPRATTPGGRTLERDVGCTRHQSVQTE--------------------------------------------------------DGTGGMARAVAKAALSPVQ-------------------EHETGRRSSSGEAG-TPLVPIVVEPARPGAKAVVPQPLGADS---------KGLQEP----------APLAP---SVPEAPRGRERWVLEVVEERTTLSGPRSKPASPKLSP-------EPQTPSLAPAKCSAPSSAVTPVPPAS-------LLGSG------------------TKPQVGLTSRCP--AEAVPPAGLTKKGVSSPAPPGP------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AKH8-1", "uniprot_id": "A0A8M3AKH8_DANRE", "id": "A0A8M3AKH8-1", "name": "non-specific serine/threonine protein kinase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDSMDDSGIIRRRRMQKDLPLPRKSSGCRTSNRKSLILTSTSPTLPR--PHSPLPGH-------------------------------------------------------------IGSSPLDSPRTFSPS------APAHFSFASSRR--------ADGRRWSLASLPSSGYGTNTPSSTSSS--SSQERLHQLPF--QPTLDELHFLTKHFG--------------------------------------------------------------------------STESITDDDG-RRSPHMRPRSRSLSPGRSSSCYDNEIVMMNHVYKERFPKATAQMEERLADFIESYSPENVLPLADG--VLSFIHHQIAELSRNCLTKSREGLITTVYFYELQENLEKLLHEAYERSESSELTFITELVKKLFIIISRPARLLECLEFNPEEFYHLLEAAEDHAKEGQLMKADIPRYIISQLGLTRDPLEDMVNLE---------------------------------------------SYDSE-GPHTPET-----------------------------------------------DDSAEGKL---KAIKP-PCESDFQTIKLISNGAYGAVYLVRHRETRQRFAMKKINKQNLILRNQIQQAFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNIGALPVDMARMYFAETVLALEYIHNYGIVHRDLKPDNLLITSMGHIKLTDFGLSKMGLMNLTTNLYEGHIEKDAREFLDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVITDYIEWPNG-DEALPADAQSLISSLLQTNPLVRLGTG-GAFEVKQHSFFSGLDWNGLLRQKAEFIPHLESEEDTSYFDTRSERYRHINSYDEDDTNDDEPVEIRQFSSCSPRFSKVYS--------------------SMEHLSQLEQKTPVVTRREHK------GRRDDKITKRESFGS---------------FSMRDKSWRTGSPEMKRLSCSESLYMEGDCS-PPMGARRRFSALMDTHRFASSQEGDGERQ-----------VTAKATGSSEGAVPPSSPSANEQRNGKEVMSISSSKSTDKASRPGEVSAPQTIPST-GAPAVISRDLVAIGDPVGQRATKDLVLRRAR------HQQLSSDG--EKRTSRPGNK--VIKSASATALSVIIPGVEQHGNSPLASPMSPR---SLSSNPSSRDSSPSRDYCPTVTVPRSPITIQRSGKKYGFTLRAIRVYIGDTDVYSVHHIVWHVEDGGPAQEAGLCAGDLITHVNGESVHGLVHTEVVELILKSGNKVTVTTTPFENTSIKVGPARRSSYKSKMARR---SKR-TVKEGQESKRRGSLFRKITKQSNLLHTSRSLSSLNRSLSSSDSLPGSPTHSLSGHSPTQSYRSTPESSHLGASSQSSSPASSTPNSPAT--TQHMRPSSLHGLSPKLHRQYRSARCKSAGNIPLSPLAHTPSPTQSSPPPLPGHTVGSSNTTQTFPAKLHSSPPIIRPRPKSAEPPRSPLLKRVQSAEKLGSPLSSSSEKKGGIGVMRKHSLEVGHSDYRKDGFHCELGLQSLVEIEGENLASAPTNSPSPTQPTPLPPETGVLKPVRKLGRQESPLSRDALLAGRERERERERERERTGKANEPSRPTESKPAAVTPPGSKTSPNSETSQRHTSTIQECCLVKPQTWQPPLTKSSPIASESKSNIVTSIPSPLTTVSSPSTKTIDQSSIREEGNDDKGSLTKIPQSQTLGTTKSPLSLIPSELINKDLLEKGGNDNGKKQVKSDVGNTSAQGKPSIPCSPPVKTTSTEVTKANEGFGNGDSLKKGVLDPHSRTSDVRVRTALAPSKGLVPSHPPQTQCSALGKLRQDKGLSAVSCYRGSFDWEDKCLLEVVEEHSPSPTPSPTGVPPDLLKSQPPAERTGLVTHLTSTGKSIGAVKGGTQEGPKAKDTNKSLEITQACAPGRPESSPEGRPNSKGASPTSSSPQVKTLITPKNGS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUQ9-1", "uniprot_id": "Q9VUQ9_DROME", "id": "Q9VUQ9-1", "name": "non-specific serine/threonine protein kinase", "aln": "MSRQEGAASRPADGATGPVASSSSSTSSNHSVSAVLGSKISTSTPQKNDEHQEQEFINQSVASEIEAMSISDSASAESSSGATATATATMSGSPVPKRHLSTANLSRIRPQSSYSARVLIFDDSDQEAAAAAAALAAASSSCNSSVKSCSGLELLPTSPAKLSIGNDSTNGSSMMRNLNLTKSSSGGLSGSSSSLHSRGYTALLRKISYQQHTNSLRAVSGETSNLLRMRHSSLGKSAPCLTGNYFRHELTAPLPVQPPGFGASPLGGHNISRSGSCAGIGLAKHHHHHHLHGVVMRGSAGGGAGSGGGSSSGVAHHRLSLVTNSAAVAAAGGSRTHSPYSASPVDSPRLNSPMPFAFAPIKRIASCRGVVADGRRWSVASLPSSGYGTTPGSSNLSSQCSSQEGLNQLAHNIPPGVQEADAAAVAAGACCAEHLKQHCPKHCALLLAVSQKQLTPQPPKPTQLQPQKSMTAACVNCCAELSVTCGGQQAGGGAANGGSSANSSGSSAMQVGGRMSPYFRPRSRSLSSPSRSPIVDNEIAVMNTLYKERFPKATQQMEERLKLFINENKSAACNSFRDSQPIVRFVHHQVLEMARDCLHKSEAKLITSQYFYELSENLERLLVETKEKSPE-AAAELNGVIKKLLLIISRPARLLECLEFDPQEFYELLEAAEGHAKAMPVIKADIPQYIIHKLGLNRDPIAELQQELRETQQMCSEQVTVDADPLHPGGSLLLNSPLTSAAKQLSSLALDAIAMDSGSGTATPQQPPQTPVATCDTAPSFALAISQMNEEKGGSSSAVGGGSSSKVAGAEGITGGSAATATGSGAQQPSPQENDFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVFAERDILSFADNPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETVLAVEYLHSYGIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGYIDSETRQFSDKQVYGTPEYIAPEVILRQGYGKPVDWWSMGIILYEFLIGCVPFFGETTEELFAHTVNDDIEWPDSEDWPVQAEAKDIISQLLQQNPRDRLGTQSGALEMKEHEYFLGMDWNSLLRQKAEFVPQLSHDDDTSYFDTRMDRYNHDLGGEDTDDTDDTPVFG-SFNSYTPQYRKQHYSWSRHATPTSTDGAKPTGPPPLSSLPSRAQETPAATVGATSTGALPKLKSGMGSGSGSGSGSGSGSASHDGVVNKFLNTPQLRKLDLSSSCLKVPSTPDADYLPELLHNVTIGNDAELRMLKHYLQQPNPGATQRMQQRHSMPPNTTTIISTPATPPPTQTQATMAATPPTATVGSFSRSTPESSQTDSDDFSPQINRKRKGVCARDILPRFSISIEDETISAGSSSTENMNLPREQSPLALQHQPKSMDGSTSGSSVKHHRSRSIVKSASALGLSLMTSLDNSQLAAQLCGIQSPGGGGNGSSTASSRDTSPCRELSPLVTNLKPPIIIRRGPRGFGFTVHTIRVYYGDTDFYTMHHLVMAVDEGSPAFEAGLRPADLITHVNGEAVQGLFHTQVLQLLLSGGEHVTLRATPLEHTSIQSGGRKRDLMQSKLAKKGVNRQKKQTKREHDKKRKTSLFRRISSKRANAEMQQYSAGTSSPTTPSARNLSPLDSSYHSSCCQSAANSSSQSTSPSSSSPNTPTGSSGSNHGGNAGSVAVAPSALSVQLPSAPPPTQLVLLPHVGAVVGSNPTSVGN-VPVSPTGVVPQLYQRPSTLHGLKHKLHAATAVIAGGGNANNPAGG--LKTLHTTNNNSLPNRRKSVGHIPLSPLARTPSPSPLPSSPTR-SPSPLAFPLVGHQPGASN-TTQSYSPGSTLP---TLQTAVNANTKKAGFARTKSAE---PSSPLLRRALSPDRLHPRSAETKISPLCCSPPIKQPTHQRVVTTTWRSTPGGSASGAG----------------------------------------------------------GAVLGAPSVQPLQLVPAAS----------------EESQRQTAMATVVSTTAAGTDPSATAVVTLANCEPLPRIAEE---------KDSPTSTQ--------DSSSVSEGFMPAIEEFAEGESSSSPTQTLEKPTKVKATEQPEMEP-------AGKSKKVDQGKTTTPGTPKTKPHNSG---CKTSMTTTKP-----------------ASPSVTISTAPRKDTSAVTGGGSSGSGGSAATSAAKQRK---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*: . :: * *.* **:. *. * *** ** *.* .** . ** :* *:**. :* *******:**********.. **. ** **** *:**.. * ::* . : * *: * : : * * ** .********. .. ****.:** :********* ****:* * . .. .: *. :: *:***: *::*:** **. ***: *****.****:** :: *:* . : :. ::***::**************:*:***.******.*** ::*:***:*** :***.***: :: . ** *. **: . : . * :* * *.**: :**************:*: ************:*******::*.*.*****:**:*****.*:*****::***:**********.*******.**.:***:********:**:*.****************::****************.*:******:*:.::*:* **** ***********************:*********:*******:*.****.:.:.* * **:. * .: ::*: :**.*** ** ***: **:*:*:*.:* .:**..********:*:*. ::******** :**.* . :: * .:: ** .*.* :*:: * : .:. *.. :**. : . . .. *. : : :. .*. :* * .:: :: .:* .: * . : . . : : : . .. . . : . *. : ... *: . :. . . * :*::: * * : ** * * . . : . ::***** .**:: . : : : *.. ** . **..****:**.*: .* *: :.** *:*. : :***:::**** **:*.*::**:* *::*.** **** ..*********.*:*:.*.:*::*:*..*::*:: :**:*:***: * :*. ::*:*:: :: .* ::.*:: ****:*:.: . .: :. . . :.* .. . . . : .*:.:*: .:** .:...** .* .. : : **:* *. : . .* : * : . . . **. : : . * : : ***::..:: :: :*. . ** :::::: . . : : : : . .. . *.: : . * :. . ... :: * .: : :. . . : . ..*. .. :. . *. *.: .* . .. : .. *. .. . ::. *. . . :* : : . . . . :: . .* : : . :. . . . * . . .:.:. . ", "identical_positions": 538, "similar_positions": 459, "identity": "23.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-223", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJL6-1", "uniprot_id": "METRL_RAT", "id": "Q5RJL6-1", "name": "Meteorin-like protein", "aln": "MRGVVWAARRRAGQQWPRSPGPGPGPPPPPPLLLLLLLLLGGASAQYSSDLCSWKGSGLTREAHSKEVEQVYLRCSAGSVEWMYPTGALIVNLRPNTFSPAQNLTVCIKPFRDSSGANIYLEKTGELRLLVRDVRGEPGQVQCFSLEQGGLFVEATPQQDISRRTTGFQYELMSGQRGLDLHVLSAPCRPCSDTEVLLAICTSDFVVRGFIEDVTHVPEQQVS---VIHLRVSRLHRQKSRVFQPAPEDSG--HWLGHVTTLLQCGVRPGHGEFLFTGHVHFGEAQLGCAPRFSDFQKMYRKAEERGINPCEINME", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VE43-1", "uniprot_id": "METRL_MOUSE", "id": "Q8VE43-1", "name": "Meteorin-like protein", "aln": "MRGAVWAARRRAGQQWPRSPGPGPGPPPPPPLLLLLLLLLGGASAQYSSDLCSWKGSGLTREARSKEVEQVYLRCSAGSVEWMYPTGALIVNLRPNTFSPAQNLTVCIKPFRDSSGANIYLEKTGELRLLVRDIRGEPGQVQCFSLEQGGLFVEATPQQDISRRTTGFQYELMSGQRGLDLHVLSAPCRPCSDTEVLLAICTSDFVVRGFIEDVTHVPEQQVS---VIYLRVNRLHRQKSRVFQPAPEDSG--HWLGHVTTLLQCGVRPGHGEFLFTGHVHFGEAQLGCAPRFSDFQRMYRKAEEMGINPCEINME", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q641Q3-1", "uniprot_id": "METRL_HUMAN", "id": "Q641Q3-1", "name": "Meteorin-like protein", "aln": "MRGAARAAWGRAGQPWPRPPAPGPPPPPLPLLLLLLAGLLGGAGAQYSSDRCSWKGSGLTHEAHRKEVEQVYLRCAAGAVEWMYPTGALIVNLRPNTFSPARHLTVCIRSFTDSSGANIYLEKTGELRLLVPDGDGRPGRVQCFGLEQGGLFVEATPQQDIGRRTTGFQYELVRRHRASDLHELSAPCRPCSDTEVLLAVCTSDFAVRGSIQQVTHEPERQDS---AIHLRVSRLYRQKSRVFEPVPEGDG--HWQGRVRTLLECGVRPGHGDFLFTGHMHFGEARLGCAPRFKDFQRMYRDAQERGLNPCEVGTD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PVC4-1", "uniprot_id": "A0A8M1PVC4_DANRE", "id": "A0A8M1PVC4-1", "name": "Meteorin-like protein", "aln": "-----------------------------MLLLLVLSAVVLCGCAQYSSDQCSWTGSGLTHESHARDVEQVYLRCAEGSLQWLYPTGAVMVNLRPN-LPSSADLRVCVKPRRDSRGATVLLERAGALRVLLSEEEQAAGRVRCFSLQEGALFLEASVQRDISRRITAFQYQLSYAHT-ADQHTDS--CRPCADEELLLSVCTSDFVARGRISRVEDNDEDEDEDGVSVVLSVSRVYRQKSRIFVSAGGGRGRDRWTGRVQILQRCDPQAGPTEFLFTGALRFGDAWLGCAPLYTDFLRVYQAARDAGTNPCTINTD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:* :: . ****** ***.*****:*:: ::********: *:::*:*****::****** :..: .* **::. ** **.: **::* **:*: : .*:*:**.*::*.**:**: *:**.** *.***:* : * * * ****:* *:**::*****..** *. * . * : . : * *.*::*****:* .. . * :* *:* * .*. :.* :***** ::**:* ***** :.** ::*: *.: * *** :. :", "identical_positions": 131, "similar_positions": 84, "identity": "41.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-234", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJQ8-1", "uniprot_id": "D3ZJQ8_RAT", "id": "D3ZJQ8-1", "name": "", "aln": "MSVHRCCQVQSPKPLVSVELPSRYRSCPPDCNFLCSVCHGVLKRPMRLPCSHIFCKKCIFQWLARQNTCPCCRKEVKRRKMVQVNKLRKTIGRLQVKCKNAAAGCLVTCPLAHRKGHQDSCPFELMACPNEGCTAQVLRGVLDEHRQHCQQNGQQRCPLGCGATLAALEGEQHNCYRELRDAWVQRHERNRTLLLNLLGRVRRVYRTTNLIRRQLAQLSNFLEDD-TLLLN--ARVQETEVAPE----PEMWGAQGQGVL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ29-1", "uniprot_id": "RN151_MOUSE", "id": "Q9CQ29-1", "name": "RING finger protein 151", "aln": "---------------MSGGYDLNLFASPPDCKFLCSVCHGVLKRPTRLPCSHIFCKKCIFRWLARQNTCPCCRKEVTRRKMVEVNKLRKTIGRLQVKCKNAAAGCLDTHPLAHRKEHQDSCPFELMACPNEGCTVQVLRGVLDEHRQHCQQNGQQRCPLGCGSTLAALEGEHHNCYRELRDAWVQRHERNRTLLLGLLGRVRRVHLTTSIIHQQLAQLSNFLEDDDNLLLN--AQVQETEVTPE----AEMRGTQGQSVL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2KHN1-1", "uniprot_id": "RN151_HUMAN", "id": "Q2KHN1-1", "name": "RING finger protein 151", "aln": "---------------MGGGYDLNLFASPPDSNFVCSVCHGVLKRPARLPCSHIFCKKCILRWLARQKTCPCCRKEVKRKKVVHMNKLRKTIGRLEVKCKNADAGCIVTCPLAHRKGHQDSCPFELTACPNEGCTSQVPRGTLAEHRQHCQQGSQQRCPLGCGATLDPAERARHNCYRELHNAWSVRQERRRPLLLSLLRRVRWLDQATSVVRRELAELSNFLEEDTALLEG--APQEEAEAAPEGNVGAEVVGEPRANIPCK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q0M8-1", "uniprot_id": "A0A8M9Q0M8_DANRE", "id": "A0A8M9Q0M8-1", "name": "", "aln": "---------------MTGGYEVDQFVDPPDDDLICVICRAVLRCPVRLKCNHVFCKECILQWMKRQVKCPCCRQSIDQNQMLVLFKLSKSIGRLSVKCRNGQQGCRATFPLSNEYLHISTCPYEWQICPHEGCGQQVLRKDVQAHDQSCTHWR-QLCPMGCGTLLVRENQTQHNCYRELQQRYLAERRKQRAIAANLRRKMQRMQSRMAQIKRQINLMCESLEVGDLETEAGEGTSAWTDASPSSSRHRHTYNSRIRFI---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *** .::* :*:.**: * ** *.*:***:**::*: ** .*****:.: :.::: : ** *:****.***:*. ** * **::. * .:**:* **:*** ** * : * * * : * **:***: * : :*******:: : .:.:.*.: .* ::: : ::::: :.: ** . . ::.:*. . . : ", "identical_positions": 75, "similar_positions": 74, "identity": "28.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-243", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M7H6-1", "uniprot_id": "F1M7H6_RAT", "id": "F1M7H6-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METNLLAAGRSYGLVDGLGVHMETTVCRPVLSPTHINATASETFTVLQQKMRIVEEQTSSLRDDLIMLGYGDRRCQLQTSDYLEDPVSQKVTSPIPNEVVCPESRGILWKNYEFLANRMCYLENLIQPLKMNIFHLQTEKDLNPQKAAFLKDQLNTIQGEHFKDLKLLQLEVMNLRQQLKVVKEEEDRAQDEVQRLTATLEIATETKKNAAVIEEELKTTKRKMNLKIQELRRQLAQEEHVRASLEKSASSMLLKVHEMESAVEAERQQVHTLQQKCIDLHSSMQTTQELLAQEQQKSNGLEMTASQLKSDLISRDNLIYKLVEENKSTQMSLKKEHEENTYLKSEVLSLQDISGKAQVLNDQLSKKCSELTSMLKAVKLENSRIIAEHHATLKVEQKMITETFQEQNLLLDTAHASITGELQTVQNDKAQLQMHLDHLILEHNQCLQKAQEAEKRTMAQKELLESTIARLRGELEASMQEKKSLLEKNEWFQREQVNKSEKGVAKEKCNLEKELAESKEDTNVLNQNLQILVEENKHLTDKMASLEHHKATSDYQGFAQQKVEKALEKITESKNKLAYEKGKLQIKVKQLEEQLHTFTETRLHNDHLQRQNKALEVKHAQ---------------------IKSLLGKNEEELAEAVKCRDAALKESQKLKGDLEALEDRENKKVGNFQKQLAEAKEDNCKVTIMLENVLASHSKMQGALEKVQIELGRRDSEIAGLKKERSLNQQRVQKLEAEVDQWQARMLIVEAQHSNEMEPLQKSLDVTREDNRKLAMSLEQALQTNGHLQSKLDHLQEKLESKERERQNLEAFKERVAEESKVEAELHAERIEALRKQFQTERETAKKVSHREVSELKKALDEANFRSVEVSRTNRELRHKATELEKVVNSNKEKLKNQRAQIRMHLSAKANSAQNMERMKQIEMELRQMEIIKDQYQKKNYEQSLSIQRFVSEMNALQKEMEMLAKSQYETSARNKQQELRLVAERKIRQELESRCKDLEDTIRHLRKCKEATENKLKEASVESEQITANLEEAHRWFKCRFDGLQLELTKN--RLQRLPREDRWLEENQD----MRHNIATSQSVLHRWETKQNLGLMPKKYHSDTERKK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CDI7-1", "uniprot_id": "CC150_MOUSE", "id": "Q8CDI7-1", "name": "Coiled-coil domain-containing protein 150", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METNLLPGGPSYGLLDESGVQMETTVCRPVLSPTHINGTASETFTVLQQKMRIVEEQTSSLRDDLIMLGYGDRRGQLETPNYLEDPASQKAISPIPNEVICPESPGNLWRNYEFLVNRMCYLENLIQSLKMNIFHLQTEKESNPQKTAFLNDQLNIIQGEHSKGLKLLQLEVMNLRQQLKVVKEEEDRAQDEMQRLTATLEIATETKKNAAVIEEELKTTKRKMNLKIQELRRQLAQEKLVRESLETSASSMLLKVQEMGSVVEAERQQVHALQEKCTALHSSMKTTQDLLAQEQRKNEDLGMTISQLKSDLNSRDNLICKLVEENKATQISLKKEHEENIYLKSEILSLQDVSGKAQVLNDQLSKKCSELTSMLQVVKMENSRIIAEHQAILKVEQKMITETFQEQNLLLDAAHASITGELQAVQNEKAQLQIHLDHLILEHNQCLQKSQEAEKRTVVQKELLESTIARLQGELKASLQEKKSLLEKNEWFQR-EVNKTEKEVAKEKCNLEKELAESKEDINVLNQNLQTLMEENKHLTNKMASLEHHKATSDYQG----KVEKALEKITDSKNMLAYEKGKLQTKVKQLEAQLHTFAETMLQKDHLHKLNKALEVKYTQANSELSASKAYLEQTEAHLKEMKSILGKNEEELAQAVKCRDAALKESQKLKGDLKALEDRESKKVGNFQKQLAEAKEDNCKVTIMLENVLASHSKMQGALEKVQIELGRRDSEIAGLKKERSLNQQRVQKLEAEVDQWQARMLIVEAQHGSEIEPLQKSLDITREDNRKLAMSLEQALQTNGHLQSKLDHLQEKLESKERERQSLEAFKEQVAEESKVEAELHAERIEALRKQFQTERETAKKASQREVSELKKALDEANFRSVEVSRANRELRHKATELEKVVNSNKEKLKNQRAQIKLHLSAKANNAQNMERMKQIEMELRQMEIIKDQYQKKNYEQSLSIQRFVSEMNTLQKEMELLTKSQYETSARNKQQELRLVAERKMRLELENRCKELEETIRHLKRCKEATENKLKEASVESEQITANLEEAHRWFKCRFDGLQLELTKN--RLQRLPREDRWLEENQD----MMHNVATSQSVLHRWETKQ-------KYHSDTERKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCX0-1", "uniprot_id": "CC150_HUMAN", "id": "Q8NCX0-1", "name": "Coiled-coil domain-containing protein 150", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDCKVHMETTVSRPVLSPTHINATASETFTVLQQRMRIVEEQTSSLRDDLIMLDFGEKRGYLEAPDCLEDLDSQKVISPIQNEAICAGKTDILWKNCEFLVNRMCRLESLMQSLKMNIFRLQTEKDLNPQKTAFLKDRLNAIQEEHSKDLKLLHLEVMNLRQQLRAVKEEEDKAQDEVQRLTATLKIASQTKKNAAIIEEELKTTKRKMNLKIQELRRQLAQEKYLRESLEKSASAMLLKIQEMGSTVEVERKQVHILQQNCIALRDSIQSAQELLAQEQKKKEELEIATSQLKSDLTSRDDLISKLVEENKNLQISFNKEHEENAYLRSEIMSLHEASEKAQVLNDQLTKKCSELSCMLQTVTMEKARIIADHQAILQVEQKMMTQTFQEQNLLLDAAHASITNELQTVQNEKTQLQAHLDHLILEHNQCIQKAQDAEKRTAVQKELLESTIARLRGELEASMQEKKSLLEEKERFQR-EVNKTEKEIVQERCNLEKELAKNKVDINTLTHNLQTLEEENKHLADQMASLELQQVTSDYHG----LAQQKVEKITESKNKLAYENGKLQIKVKQLEEQVQSFTDTSLQNDHLRKMNKYLQTKYAQANSELSAKRVHLQQADAHLKEVKSILERSKEELSRTVKCRNAALKESQKLKEDLEAVEDRENKKVGNFQRQLAEAKEDNCKVTIMLENVLASHSKMQGALEKVQIELGRRDSEIAGLKKERDLNQQRVQKLEAEVDQWQARMLVMEDQHNSEIESLQKALGVAREDNRKLAMSLEQALQTNNHLQTKLDHIQEQLESKELERQNLETFKDRMTEESKVEAELHAERIEALRKQFQTERETTKKVAQREVAELKKALDEANFRSVEVSRTNRELRQKLAELEKILESNKEKIKNQKTQIKLHLSAKANNAQNIERMKQIEKELKQMELIKDQYQKKNYEQSLSIQRFVCEMTNLQKEMQMLAKSQYDASVRNKQQELHLEAERKIRQELENRCQELEETVRHLKKCKEATENTLKEASVESEQITANLEEAHRWFKHRFDGLQLELTKN--RLQRPSGEDRWQEKDQD----VKHDVMSNQSVLHRWERKQNLRPMPKKYHSEVQRK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TAN8-1", "uniprot_id": "A0AB32TAN8_DANRE", "id": "A0AB32TAN8-1", "name": "", "aln": "MYLKICLPVNFYSACLSCFLPQCVSCSCLSIYLSIYLSIYLSIYLSICLSVCLSVCLSVCLSVCLCATIYLFVCLCLSVCLFVCPSVRLYLSVCVPLSIYLSVCLCLCLSVCLSVRPSVSVCLSVCLCATIYLFVCLSVCLSIYLSIYLSIYLSIYLSIYLSIYLSIYLSVCLSVCLSVCLSVCVPLSVCVCLSVRPSVSIYLSVFLSVCVGLSVCISVCLSVCLSVCLYVCLCLSVRPSVYIYLSVCLAGWLSVWACLSVYLSAFLSVCVPLSVCLSVRPSICPSLSIYLSIYLSIYLSIYLSIYLSICLSVCLSVCLSVCLSVCHYLSICLSVCPSVRPSVRPSVSIYLSGCLSLSVCLSIYLSVCLSVCLSVCVGLSVCISVCLSVCLCLSVCLYVCLCLSLSIYLSIYLSVCLSVCLSVCLSVCMSVYLPICLSIVLSVYHFIHIFFPVCLSVCPSVHIFFSCLTCVSISLCVSVSVCPSVCPAMSRSVVCPVSVSAAAPESLSVLQRRLQTAEQQTEELVRTLGSLGASADQQHLQN-----SVGTRPISPVNIQRAPSATGESLLWRQCETLVARVCRLESVLHALKLTAFRLETERQLNPSHPAGLQERLISLQEQHEREQRASLLELLRLQDELQQTREDRQEAQREVIRLTEALENTMSSQK-----------------------KEQMAQETAAHLEFEKSHNALLQRVEEMETVVERERAQVEILQRDCHALRLDGHADRAELKKREEKILDLQRECQQLRDQSGVKEILISQLTKEIKCVKTVLQKQQQENSRLIRDGRDLRAAADQVQVLNEKLEVQCSELSSALHALTQENAKLQSEYQNNIKAERDRVSKHLKEQDLLLDTARRNIQAELQRAITEKLSLQKELETLKVEHSRLQQSSVFSQETAVNHLQMLEQTIERLKGEIGSAVRDGEMLREERDHIHS-QMSSAVCLLEKEKNILETQLTEIKAELTTVNSALQKQTEENKELMESLAAMEHQQVT-------HRQVEQMLWEMTDGKNKLAYEKGKLQARVQQMAAELKTLKAECAQHCQT---------------------------------------------------------------KTALENSYTQTQRENQALKDQLQQQHRDMNEVAQTLENVLSSHTHLQHNTQTLNAELRETAEEMQTLRRERLEAMQEIQRLEDKVENHNA-------ANTEKVESLQKALDEAQLDNRKLGQSLEQALQENHNTRQKLNTVVESRE--------------AELKEAKDEIRRLTEQLDSLKNLLNREKEFARKSAHR----LKKALNDASVKSGDLSQANQELREKVSELEKQVFNQKSQLN--------QYVDKRTALSNSLRIKDLETEIKDLEEAKDEYKKRSYEQSQCLLRLRSEMVSLQSELISLSSSQQGE----------LQAQRETSHKLQEKCQLLEERLKLLQDERDDAEIRLREVCMESQEITENMDEDHRGLRSKSHSFNDEPQKLTESLWRMRKERSCSTPVQTRVCFFDPELEPWASALQRWEIKKELGRIAGNYKPRRHVRTLTT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 283, "similar_positions": 387, "identity": "17.75%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-249", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0DJH9-1", "uniprot_id": "RD3L_HUMAN", "id": "P0DJH9-1", "name": "Protein RD3-like", "aln": "--------------MPLFGWMKWPKNDSYKPTHYPGSDIVTKTLLRELKWHLKERERLIQEIENEQKVKKTGVDYNWLRNYQNPHTTIPVTEQRQLEVLCSQVQPCQTGTILSRFREVLAENDVLPWEIVYIFKQVLKDFLSSSDRGSEQE--------------DLEDSGSMDCSAPSVIQGDSSKRADKDEIPTISSYVDKNTKDRFPVFSHRIWNLPYYHPSS--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F3D1-1", "uniprot_id": "E7F3D1_DANRE", "id": "E7F3D1-1", "name": "", "aln": "MESRHHGPRPLRPTSPVMPFAGWPHTNGCVAPGGSG-----RMLLREMLWQLEQRALQFQEEEIQYCISRGILGYRHRPAYPNLLALIPASEHRQLEHLCGRIPPSHSAIVLARLHDLLAHNDIPPWELVSVFKQVLKEFLRRHEDGMQRRPAPSTFLCAPGSPVESNDRNHMAGNASNALSEESGK--HREEIPTISSYVDKHLHSACPYSIHRDWSLPFCHPFAYEAYSTTL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: : **:.:. .. .* : ****: *:*::* :** * : :.: :.*. * * : **.:*:**** **.:: *.::. :*:*::::**.**: ***:* :******:** : * ::. : :* . * .*...:. :*.* .::***********: :. * ** *.**: ** : ", "identical_positions": 70, "similar_positions": 69, "identity": "29.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-252", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZVR8-1", "uniprot_id": "D3ZVR8_RAT", "id": "D3ZVR8-1", "name": "Protein phosphatase 1 regulatory inhibitor subunit 16B", "aln": "MAEHLELLAEMPMVGRMSTQERLKHAQKRRAQQVKMWAQAEKEAHGNKKGHGERPRKEVAGLKPQKQVHFPPSIALLEAAARNDLEEVRQFLTSGVSPNLANEDGLTALHQCCIDDFQEMVQQLLEAGADVNARDSECWTPLHAAATCGHLHLVELLISRGADLLAVNTDGNMPYDLCEDEQTLDYLETAMANRGITQDSIEEARAVPELCMLNDLQNLLHAGANLNDPLDHGATLLHIAAANGFSEVATLLLEQGASLSAKDHDGWEPLHAAAYWGQVHLVELLVAHGADLNGKSLMDETPLDVCGDEEVRAKLLELKHKQDALLRAQGRQRSLLRRRTSSAGSRGKVVRRVSLTHRTNLYRKEHAQEAIVWQQPPVTSPEPLED-EDRQTDAELRLQP-----------PEDDSPEVAR----PHNGQVGAPPGRHLYSKRLDRSVSYHLSP-EESCSPDALIRDKAHHTLAELKRQRAAAKLQR---------------PAPEGPG---TCEPGLSVDTETSQPECGFSTS-GDPPLLKLTAPSEEASVEKRPCCLLM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q923M0-1", "uniprot_id": "PP16A_MOUSE", "id": "Q923M0-1", "name": "Protein phosphatase 1 regulatory subunit 16A", "aln": "MAEHLELLAEMPMVGRMSTQERLKHAQKRRAQQVKMWAQAEKEAHS-KKGHGERPWKEVAGLRPRKHVLFPPSVALLEAAARNDLEEVRQFLTSGVSPNLANEDGLTALHQCCIDDFQEMAQQLLDAGADVNARDSECWTPLHAAATCGHLHLVELLISRGADLLAVNSDGNMPYDLCEDAQTLDCLETAMANQGITQEGIEEARAVPELCMLNDLQNRLQAGANLSDPLDHGATLLHIAAANGFSEVATLLLEQGASLSAKDHDGWEPLHAAAYWGQVHLVELLVAHGADLNGKSLVDETPLDVCGDEEVRAKLLELKHKQDALLRAQGRQRSLLRRRTSSAGSRGKVVRRVSLTHRTNLYRKEHAQEAIVWQQPPPTSPEPLED-EDRQTDAELRLQP-----------PEDDGPEVAR----PHNGQVGAPPGRHLYSKRLDRSVSYHLSP-EENSAPDALVRDKAHHTLAELKRQRAAAKLQR---------------PAPEGPE---TFEPGLSVDAGTSQPDCGFSTI-GDPPLLKLTAPSEEASVEKRPCCLLM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96I34-1", "uniprot_id": "PP16A_HUMAN", "id": "Q96I34-1", "name": "Protein phosphatase 1 regulatory subunit 16A", "aln": "MAEHLELLAEMPMVGRMSTQERLKHAQKRRAQQVKMWAQAEKEAQG-KKGPGERPRKEAASQGLLKQVLFPPSVVLLEAAARNDLEEVRQFLGSGVSPDLANEDGLTALHQCCIDDFREMVQQLLEAGANINACDSECWTPLHAAATCGHLHLVELLIASGANLLAVNTDGNMPYDLCDDEQTLDCLETAMADRGITQDSIEAARAVPELRMLDDIRSRLQAGADLHAPLDHGATLLHVAAANGFSEAAALLLEHRASLSAKDQDGWEPLHAAAYWGQVPLVELLVAHGADLNAKSLMDETPLDVCGDEEVRAKLLELKHKHDALLRAQSRQRSLLRRRTSSAGSRGKVVRRVSLTQRTDLYRKQHAQEAIVWQQPPPTSPEPPEDNDDRQTGAELRPPP-----------PEEDNPEVVR----PHNGRVGGSPVRHLYSKRLDRSVSYQLSP-LDSTTPHTLVHDKAHHTLADLKRQRAAAKLQR---------------PPPEGPESPETAEPGLPGDTVTPQPDCGFRAG-GDPPLLKLTAPAVEAPVERRPCCLLM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FFN3-1", "uniprot_id": "E7FFN3_DANRE", "id": "E7FFN3-1", "name": "", "aln": "MAEHGELLAEMASIGRLSATERLKQAQKRRAQQLKGWAQMEKDSAR-----GHKADHKGDGVKKSRRVTFNSNVMLLEAAARNDIEEVRQLLNNGVSPDLFNEDGLTALHQSCIDDFLEVARCLLDAGANVNACDSELWTPLHAAATCGHTDLVQMLIEAGADLLAVNADGNMPYDLCEDEATLELIEMIMAEQGITQEKIDECRGAKERVMLTDLREMVTNGADLNVKDEQGATMLHVAAANGYMSVGELLLEHRLSPDERDADGWTPLHAAACWGQIQMVELLVAHGASLNAKSELDETPLDVCTDEEVRAKMMELKHKHDAIMKGQDKHKNTLQRRVSSTGSRGKVVRRSSVNERSSLYRREHQKEAKVWQERG-RQTEALDDDEDRQTDAELNLHASLMSSSNAIAVPPLDVGEVENGAQVIGNGSTGSFSGELQSGGLMDRSASYQLSPGSASAGGDSMSRERSHHTLADLKRQRAAAKLNKHPAPPLPLSAGTQDEPVPEGPPG--TLEPSESVQQVVAPNAVYFTQASGDPPLLKLKAPEEETTNTKEPCCGLM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** ******. :**:*: ****:********:* *** **:: *.:. :: . ::* * ..: *********:*****:* .****:* **********.***** *:.: **:***::** *** ************ .**::** **:*****:*********:* **: :* **::****: *: .*.. * ** *::. : **:* ::***:**:*****: ... ****: * . :* *** ****** ***: :*********.**.** :******** *******::*****:**:::.*.:::. *:**.**:********* *:..*:.***::* :** ***: ..*. :* :****.***. . * * ** . ** .*. . . . :***.**:*** . .:: ::::*****:**********:: * **** * **. . : .. * ********.** *:. :.*** **", "identical_positions": 284, "similar_positions": 128, "identity": "50.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-255", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M8M9-1", "uniprot_id": "LRC52_MOUSE", "id": "Q5M8M9-1", "name": "Leucine-rich repeat-containing protein 52", "aln": "MSLASGPSSKLLLFSLGMGLVSGSK--------CPNKCVCQDQ-EVACIDLHLTEYPADIPLNTRRLYLNNNKITSLPALQLGFLSDLVYLDCQNNRIREVMDYTFIGIFRLIYLDLSSNNLTSISPFSFSVLTNLVRLNISHNPHLLYLDKYVFANTTSLRYLDLRNTGLHIIDHNGFHHLVVLQTLYLSGNPWICNCSFLDFTIHLLVSHMDHPDAQNATCTEPAELKGWPITKVGNPLQYMCITHLDQQDYIFLLLIGFCIFAAGTVAAWLTGVCAVLYQN-ALRTSSGDDTEDETGSRFANQIFRSNTHLGPIRRFPELI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N7C0-1", "uniprot_id": "LRC52_HUMAN", "id": "Q8N7C0-1", "name": "Leucine-rich repeat-containing protein 52", "aln": "MSLASGPGPGWLLFSFGMGLVSGSK--------CPNNCLCQAQ-EVICTGKQLTEYPLDIPLNTRRLFLNENRITSLPAMHLGLLSDLVYLDCQNNRIREVMDYTFIGVFKLIYLDLSSNNLTSISPFTFSVLSNLVQLNIANNPHLLSLHKFTFANTTSLRYLDLRNTGLQTLDSAALYHLTTLETLFLSGNPWKCNCSFLDFAIFLIVFHMDPSDDLNATCVEPTELTGWPITRVGNPLRYMCITHLDHKDYIFLLLIGFCIFAAGTVAAWLTGVCAVLYQN-TRHKSSEED-EDEAGTRVEVSRRIFQTQTSSVQEFPQLI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TA04-1", "uniprot_id": "A0AB32TA04_DANRE", "id": "A0AB32TA04-1", "name": "", "aln": "MRVLPEPSAQSLRLVFLLVFVMDVAPSPALTAGCPDRCVCDDQLVVQCAGQQLSDFPVDLPLATRQLIISNNRIGDLPALQLNYLSDLVYLDCSNNSLTEISESTFGNLRKLAYLDLSFNSLAQIEDRTFGPLASLVMLRMTDNPGLSEIHPDAFAENAALQVLDVSRNNLTALNISSLIALPALRSLGLSGNPWRCDCDTEDLCLWIQIEGFKFQDEGQTVCQGPPDMLGQRLAEVGMQLRSECHQGLGYWDYLFFIAIGFVIFSAGTVSAWVMGVLMVLYERYSKRKSEELDSDDEEETVTRGPGGGGGNHGNGDLNKPGMQV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . *.. * : : : :* . **:.*:*: * * * . :*:::* *:** **:* :.:*:* .***::*. *********.** : *: : ** .: :* ***** *.*:.*. :*. *:.** *.::.** * :. .**:.::*: **: ...* :: .: * .*.:* ****** *:*. *: : : : :. * ::.* *.:: * ::.** *: * *. **:*:: *** **:****:**: ** ***:. : :.*. * :** : .: . . * : ", "identical_positions": 107, "similar_positions": 104, "identity": "32.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-259", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYC6-1", "uniprot_id": "Q6AYC6_RAT", "id": "Q6AYC6-1", "name": "ABI gene family member 3", "aln": "--MAELQQLQQLQEFDIPTGREALRGNHSALLRVANYCEDNYLQATDKRKALEETMAFTTQALASVAYQVGNLAGHTLRMLDLQGAALRQVEAKMSTLGQMVNMHLEKVARREIGTLATVVRLPPSQKVIPPES-LPPLTPYCRKPLNFACLDDVGHG--------------------VKDLSTQLSRTGTLSRKSIKAPATPASATLGRPPRIPEPVQLPAVPDGKLSAASSVSSLASAGSAEGASGIPQSKGQVAPATPPPPPIAPVTP------------PPPPLPAEIFLLPPPMEE--------SQPPPETELPLP----PPPALQGDELGLLPPPPPGFGPDEPSWVPAAYLEKVVTLYPYTRQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVEPSC-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BYZ1-1", "uniprot_id": "ABI3_MOUSE", "id": "Q8BYZ1-1", "name": "ABI gene family member 3", "aln": "--MAELQQLQQLQEFDIPTGREALRGNHSALLRVANYCEDNYLQATDKRKALEETMAFTTQALASVAYQVGNLAGHTLRMLDLQGAALRQVEAKMSTLGQMVNMHMEKVARREIGTLATVVRLPSNQKVIPPES-LPSLTPYHRKPLNFACLDDIGHG--------------------VKDLSTQLSRTGTLSRKSIKAPATPVSATLGRPPRIPEPVQLPAVPDGKLSAASSASSLASAGSAEGASGIPQSKGQVAPATPPPPPVAPVTP------------PPPPLSAEVFLPPPPLEV--------SQPPLEAELPLP----PPPALEGDELGLLPPPPPGFGPDEPSWVPASYLEKVVTLYPYTRQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVEPSC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2A4-1", "uniprot_id": "ABI3_HUMAN", "id": "Q9P2A4-1", "name": "ABI gene family member 3", "aln": "-----MAELQQLQEFEIPTGREALRGNHSALLRVADYCEDNYVQATDKRKALEETMAFTTQALASVAYQVGNLAGHTLRMLDLQGAALRQVEARVSTLGQMVNMHMEKVARREIGTLATVQRLPPGQKVIAPEN-LPPLTPYCRRPLNFGCLDDIGHG--------------------IKDLSTQLSRTGTLSRKSIKAPATPASATLGRPPRIPEPVHLPVVPDGRLSAASSAFSLASAGSAEGVGGAPTPKGQAAPPAPPLP--SSLDP------------PPPPAAVEVFQRPPTLEEL-------SPPPPDEELPLPLDLPPPPPLDGDELG-LPPPPPGFGPDEPSWVPASYLEKVVTLYPYTSQKDNELSFSEGTVICVTRRYSDGWCEGVSSEGTGFFPGNYVEPSC-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T6E8-1", "uniprot_id": "A0A8N7T6E8_DANRE", "id": "A0A8N7T6E8-1", "name": "", "aln": "MRDYNCKEHIDKILQDAPTARKALLDNHSNLLKVADYCQNKYLNVEDTKSVIEESKALTTQALASVTYQINNLATNLLKLLDTQTVQLKQMESSINMLTLTVAMYKEKIARGEIGVLTKQAKVPRTQKVVPPAKGLEPFRGYRRVPISYSCLDKLGHGHWQGNKTEETKTESDYEDSMSVQLSTQETSTFNWSFLGIAVPPPSVPASVGSSVAAPPDFSPASPSPSPLSVRSPSLPPFAYPDLSMLPPPLLPDDDMGDAPPPPPPPSPPPPGSVYGGSLVPPPPPPPGTNTTMTAPPPPPPPGNMSVPPPPPPPPGNMGVLPPPPPPPPGNMGVPPPPPPPPPGNMGVPPPPPPPPPGNMCIPPPPPPPPGYTGSSLPPPAPPPPQNASMAPPPPPPPPLGGKFLPPPPPPPPPF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : **.*:** .*** **:**:**:::*::. *.:..:**: *:********:**:.*** : *::** * . *:*:*: :. * * *: **:** ***.*:. ::* ***:.* . * .: * * *:.:.***.:*** :**** : * . * .* .*.....*::* . * . . . . **. *. . : . . ...: . ..** * :. * **** . : **. . ** :: : ***. : . ****** *. *.. : :. * . . *:. : . .. * *:* *. ", "identical_positions": 108, "similar_positions": 109, "identity": "26.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-264", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y272-1", "uniprot_id": "RASD1_HUMAN", "id": "Q9Y272-1", "name": "Dexamethasone-induced Ras-related protein 1", "aln": "---------------------------------------------------------------------------------------------------------------MKLAAMIKK----MCPSDSE-LSIPAKNCYRMVILGSSKVGKTAIVSRFLTGRFEDAYTPTIEDFHRKFYSIRGEVYQLDILDTSGNHPFPAMRRLSILTGDVFILVFSLDNRDSFEEVQRLRQQILDTKSCLKNKTKENVDVPLVICGNKGDR-DFYREVDQREIEQLVGDDPQRCAYFEISAKKNSSLDQMFRALFAMAKLPSEMSPDLHRKVSVQYCDVLHKKALRNKKLLRAGSGGGGGDPGDAFGIVAPFARRPSVHSDLMYIREKASAGSQAKDKERCVIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q2A6-1", "uniprot_id": "A0A8M1Q2A6_DANRE", "id": "A0A8M1Q2A6-1", "name": "", "aln": "MSRAHRSRWMYPMNIKQICLSSMCPVMDQVMQHQTRALPGGTSTPSVLLAYKNATQRLGASGFKVSALSKAGMGILKLATTQLKQQEKKARVVRASSQGKAHPPIDKKSPLDQLAALVLHGHARLQPIAHESHATKPQNCRRIVVLGAPRVGKTSILRRFLRDGFEEQYEPTCEDFHRKLYQIRGETYQIDILDASGERSFPAKRRLSILTGDIFLLVFSLDDRSSFEEVRALHTEIVAAKAALR-RSKQPLCVPTVVCANKVDLPAEQRAVSRPEVLSALG---SSCALFETSAKDSVNLEQVFEALAQRGGLPLETGPSQHRKVSIR-----SYQALRAARQAEKGSKAPACEAP--CGALYPLARRPSFGTDLRLVLGPKGNRKQSKALDKCQIQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***:: : : * * : .:** *:*:**:.:****:*: *** . **: * ** ******:*.****.**:****:**::.*** *********:*:******:*.*****: *: :*: :*:.*: ::*: : ** *:*.** * * *.: *: . :* . ** ** ***.. .*:*:*.** . ** * .*. *****:: :*** : . ** . . :. * : *:*****. :** : . .*:* ::* *.", "identical_positions": 123, "similar_positions": 78, "identity": "30.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-269", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NFT6-1", "uniprot_id": "DBF4B_HUMAN", "id": "Q8NFT6-1", "name": "Protein DBF4 homolog B", "aln": "MSEPGKGDDCLELESSMAESRLRAPDLGVSRCLGKCQKNSPGARKHPFSGKSFYLDLPAGKNLQFLTGAIQQLGGVIEGFLSKEVSYIVSSRREVKAESSGKSHRGCPSPSPSEVRVETSAMVDPKGSHPRPSRKPVDSVPLSRGKELLQKAIRNQGSISGGGSGGSSSLLTNARSWGVRILHVDEMMMHVQQLSLASLCVKKQQPKKPEGTCPAAESRTRKVARLKAPFLKIEDESRKFRPFHHQFKSFPEISFLGPKDASPFEAPTTLGSMHHTRE--------SKDGEPS--------PRSAAHTMP---RRKKGYCECCQEAFEELHVHLQSAQHRSFALEAHLYAEVDRIIAQLSHSFADIP-------------------------------------FQAGLPRWSGSPASDCDPLCP------------ETLHPHQPSHPRAASPRIRKEDSCQASVTQGRA---------------------------AGQQRWTESLDGVMGPPASHTCVSATTLLPALPKG---SREQGCLCPCPASFTQSHLVTSLALLPG--------EWSPAEDMPLHPSQENSFAPADIPVKGPLLFPEARPWLMSARCWVR--------PFPFVTWGCLIPH---DTTPLHEEVSPCPCLRLGYLYLLLTQSLWCR--VRVPSLSTAGPIPRTSHPCTLAFPSYLNDHDLGHLCQAK--------PQGWNTPQPFLHCG---FLAVDSG-------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EYS4-1", "uniprot_id": "E7EYS4_DANRE", "id": "E7EYS4-1", "name": "", "aln": "---------------------------------------MSGNVSNGLRGKSFYLHDVKRHQSVTLTDIINRLGGKVDSFLTKDVNVVVTGIKEAHN----------------DLPVDSSCATGRKQSG---TSKPLVCG--SRGKALLEKAIHSN-------DKSQSSVLANARSLGVKVYHVDGFLKIISHLDQKMRTAKKKRSKQ--------IAPQVKAGVLKSPYLKVEDCSRKFRPYYAQTLNFPSMSYSG--KCSPFELLRIPQKTDRSKDENPSKDHFGKKKEPTSSCHRLQVPLTASATLRGPTKKSSGYCECCHVAFKDQHEHLESEMHRSFVQKDSNYTEVDQLTATMNANFVCIPNEEVDPTLMKSSAGLSPLHLNHLTEMVQNTVSDNEEFLQTPLVRDCGHLPSITELFTPTLDKTENSPKPIQSLSSFSTHHQNTTSHLYPMQNNCPDAFDHDKAGVYFTCTTKVNEFQPDVLCMDLIQHSVSSIDKNPKSFSSLTSSEAKLNMLTLCSKIPCTTSGGEYDPENQNQSEVAHGHLVCHMPRNLEGACSNTVFSQKLVWNQGLSMCLNSPKILLQGEKDGNLQRCGQFEFDHRLLLSTKKYLQGIVRSPEFGMTYFPLSCFLPFPHLSDSPFPKVNKKKRDRSFTQSPKLAKRRKICHNGMQNPSWDCSTPCKRSSVPSALALAVSKVDFTTKMNNRPGDEISFADQTQTWHSRKKYFTSPSTHCLPNQVGQQDNATSKLGDHVERKIFPEDPVESRVTTHSSELDLPQLVPFYYEDNKLQRHQYNDPPELFPFFFQTPEDNSQASVSKVASSSFVAHSGASVCIESALVPNLTWSPASSESDWDSGLLSWLANAVPLQAKSDKDDMGLLLQKPHTDMQDGSYASRLCSILQPS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* .: : ******. :: **. *::*** ::.**:*:*. :*:. :*.: :: *::*. .. * * : **: . **** **:***:.: . ..**:*:**** **:: *** :: :.:*. .**::.*: : *.. **:*:**:** ******:: * .**.:*: * ..**** . .:::: .*. **: * :*: *: ::..******: **:: * **:* ****. : *:***:: * :. .*. ** :*: * * .* .* : : * ::* .... * .::* ::.* :. :.:* :. :: .:*:..: .. *. . :: : :*. ..* . *: . . .. .*: .* . *. . .* *:..: . * :: * : *:*:: ::: :.:.. .*::*. . :*: : . : * .: *: :: ** . : * *:* *.:**:. *. :. .* *:: : :: . *. : * ", "identical_positions": 146, "similar_positions": 207, "identity": "16.08%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-272", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BM75-1", "uniprot_id": "ARI5B_MOUSE", "id": "Q8BM75-1", "name": "AT-rich interactive domain-containing protein 5B", "aln": "-----------------------------------MEPNSLQWVGSPCGLHGPYIFYKAFQFHLEGKPRILSLGDFFFVR--------------------------------CTPKDPICIAELQLLWEERTSRQLLSSSKLYFLPEDTPQGRNSDHGEDEVIAVSEKVIVKLEDLVKWAHSDFSKWRCGLRATPVKT------------EAFGRNGQKEALLRYRQSTLNSGLNFKDVLKEKADLGEDEEETNVIVLSYPQYCRYRS-----MLKRIQDKPSSILTDQFALALGGIAVVSRNPQILYCRDTFDHPTLIENE-SVCDEFAPNLKGRPRKKKT-CPQRRDSFSGSKDPNNNCDGKVISKVKGEARSALTKPKN-NHNNCKKTSNEEKPKLSIGEECRADEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQKLGGYETITARRQWKHIYDELGGNPGSTSAATCTRRHYERLILPYERFIKGEEDKPLPPIKPRKQENNTQENENKTKVSGNKRIKQEMAKNKKEKENTPKPQDTSE----------------VSSEQRKEEETLN-HKSAPEPLPAPEVKGKPEGHKDLGARAPVSRADPEKANETDQGSNSEKEAEEMGDKGLAPLLPSPPLPPEKDSAPTPGAGKQP-LASPSTQMDSKQEAKPCCFTESPEKDLQGAPFSSFSATKPPLTSQNEAEEEQLPATANYIANCTVKVDQLGSDDIHTALKQTPKVLVVQSFDMF-----KDKDLTGPMNENHGLNYTPLLYSRGNPGIMSPLAKKKLLSQVSGASLSSSYPYGSPPPLISKKKLIAREDLCSGLSQGHHSQS--SDHTAVSRPSVIQHVQSFKNKASEDRKSINDIFKHDKLS----RSDAHRCGFSKHQLGSLADSYILKQETQEGKDKLLEKRAVSHAHVPSFLADFYSSPHLHSLYRHTEHHLHNEQSSKYAA--RDAYQ-ESENGA-FLSHKHPEKIHVNYLASLHLQDKKVAAAEASTDDQPTDLSLPKNP---HKLTSKVLGLAHSTSGSQEIKGASQFQVVSNQSR--DCHPKACRVSPMTMSGPKKYPESLARS-GKPHQVRLENFR--KMEGMVHPILHRKMSPQNIGAARPIKRSLEDLDLVIAGKKARAVSPLDPA--KEASGKEKASEQESEGNKGAYGG--HSGAASEGHKLPLSTPIFPGLYSGSLCN------SGLNSRLPAGYSHSLQYLKNQTVLSPLMQPLAFHSLVMQRGIFTSPTNSQQLYRHLAAATPVGSSYGDLLHNSIYPLAGINPQAAFPSSQLSSVHPSTKL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AEL5-1", "uniprot_id": "A0A8I6AEL5_RAT", "id": "A0A8I6AEL5-1", "name": "AT-rich interactive domain-containing protein 5B", "aln": "-----------------------------------MEPNSLQWVGSPCGLHGPYIFYKAFQFHLEGKPRILSLGDFFFVR--------------------------------CTPKDPICIAELQLLWEERTSRQLLSSSKLYFLPEDTPQGRNSDHGEDEVIAVSEKVIVKLEDLVKWAHSDFSKWRCGLRATPVKT------------EGFGRNGQKEALLRYRQSTLNSGLNFKDVLKEKADLGEDEEENNVIVLSYPQYCRYRS-----MLKRIQDKPSSILTDQFALALGGIAVVSRNPQILYCRDTFDHPTLIENE-SVCDEFAPNLKGRPRKKKT-CPQRRDSFSGSKDPNNNCDGKVISKVKGEARSALTKPKN-NHNNCKKSSSEEKPKLSIGEECRADEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQKLGGYETITARRQWKHIYDELGGNPGSTSAATCTRRHYERLILPYERFIKGEEDKPLPPIKPRKQENNAQENENKTKVSGNKRIKQEMAKNKKEKENTPKPQDPSE----------------VSSEQRKEEETLS-QKSVPEPLPAPEVKKKPEGHKDLVVRAPVSRADPEKGNETDQGSNCEKEAEEVGDKGLAPLLPSPPLPPEKGSAPTPGAGKQP-LASPSAQMDSKQEAKPCCFPESPENDLQGAPFSSLPTTEQPLAVQPEAEEEKLPAMANYIANCTVKVDQLGSDDIHTALKQTPKVLVVQSFDMF-----KDKDLTGPMNENHGLNYTPLLYSRGNPGIMSPLAKKKLLSQVSGASLSSSYPYGSPPPLISKKKLIARDDQ----SQAHHSQS--SDHMAISRPSVIQHVQSFKNKASEDRKSINDIFKHDKLS----RSDAHRCGFSKHQLGSLADSYILKQEAQESKDKLLEKRAVSHAHVPSLLADFYSSPHLHSLYRHTEHHLHNEQSAKYAA--RDVYQ-ESENGA-FLSHKHPEKIHVNYLASLHLQDKKLAAAEASTDEQPTDLSLPKNP---HKLTSKVLGLAHSASGSQEIKGTSQFQVISSQSR--DCHPKACRVSPMTMSAPKKYPESLARS-GKPHHVRLENFR--KMEGMVHPILHRKMSPQNIGAARPIKRSLEDLDLVIAGKKARAVSPLDPA--KEASGKEKASEQESEGNKAAYSG--HSGAASEGHKVPLSSPIFPGLYSGSLCN------SGLNSRLPAGYSHSLQYLKNQTVLSPLMQPLAFHSLVMQRGIFTSPTNSQQLYRHLAAATPVGSSYGDLLHNSIYPLAAINPQAAFPSSQLSSVHPSTKL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14865-1", "uniprot_id": "ARI5B_HUMAN", "id": "Q14865-1", "name": "AT-rich interactive domain-containing protein 5B", "aln": "-----------------------------------MEPNSLQWVGSPCGLHGPYIFYKAFQFHLEGKPRILSLGDFFFVR--------------------------------CTPKDPICIAELQLLWEERTSRQLLSSSKLYFLPEDTPQGRNSDHGEDEVIAVSEKVIVKLEDLVKWVHSDFSKWRCGFHAGPVKT------------EALGRNGQKEALLKYRQSTLNSGLNFKDVLKEKADLGEDEEETNVIVLSYPQYCRYRS-----MLKRIQDKPSSILTDQFALALGGIAVVSRNPQILYCRDTFDHPTLIENE-SICDEFAPNLKGRPRKKKP-CPQRRDSFSGVKDSNNNSDGKAVAKVKCEARSALTKPKN-NHN-CKKVSNEEKPKVAIGEECRADEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQKLGGYETITARRQWKHIYDELGGNPGSTSAATCTRRHYERLILPYERFIKGEEDKPLPPIKPRKQENSSQENENKTKVSGTKRIKHEIPKSKKEKENAPKPQDAAE----------------VSSEQEKEQETLISQKSIPEPLPAADMKKKIEGYQEFSAKPLASRVDPEKDNETDQGSNSEKVAEEAGEKGPTPPLPSAPLAPEKDSALVPGASKQP-LTSPSALVDSKQESKLCCFTESPESEPQEASFPSFPTTQPPLANQNETEDDKLPAMADYIANCTVKVDQLGSDDIHNALKQTPKVLVVQSFDMF-----KDKDLTGPMNENHGLNYTPLLYSRGNPGIMSPLAKKKLLSQVSGASLSSSYPYGSPPPLISKKKLIARDDLCSSLSQTHHGQS--TDHMAVSRPSVIQHVQSFRSKPSEERKTINDIFKHEKLS----RSDPHRCSFSKHHLNPLADSYVLKQEIQEGKDKLLEKRALPHSHMPSFLADFYSSPHLHSLYRHTEHHLHNEQTSKYPS--RDMYR-ESENSS-FPSHRHQEKLHVNYLTSLHLQDKKSAAAEAPTDDQPTDLSLPKNP---HKPTGKVLGLAHSTTGPQESKGISQFQVLGSQSR--DCHPKACRVSPMTMSGPKKYPESLSRS-GKPHHVRLENFR--KMEGMVHPILHRKMSPQNIGAARPIKRSLEDLDLVIAGKKARAVSPLDPS--KEVSGKEKASEQESEGSKAAHGG--HSGGGSEGHKLPLSSPIFPGLYSGSLCN------SGLNSRLPAGYSHSLQYLKNQTVLSPLMQPLAFHSLVMQRGIFTSPTNSQQLYRHLAAATPVGSSYGDLLHNSIYPLAAINPQAAFPSSQLSSVHPSTKL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F888-1", "uniprot_id": "ARI5B_DANRE", "id": "E7F888-1", "name": "AT-rich interactive domain-containing protein 5B", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVSDLRSWKKGLQAVPLKPG---------VLKELGKNGQREALHKYRESTLNSGLNFKDVLKEKAELGEDADDKKVLVLSYPQYCRYRS-----IIARLRERPSSLLTDHVVLALGGIASLTNSTQILYCRDTFEHPTLVENE-SVCDEFAPNLKGRPRKKKLSISQRRDSQSGGARESNGVEGKTLVKMRADSKSGVSKPRNPSTGSCKRVQSENKPKGDGGDECRTDEQAFLVALYKYMKERKTPIERIPYLGFKQINLWTMFQAAQKLGGYEVITARRQWKNVYDELGGNPGSTSAATCTRRHYERLILPYERFTKGEEDKPLPPAKPRKQEGSVQESIIKAKMMPIKRPKDEQKTPRGDKDASAKVLELGM----------------EDMEELQE-------KQNSQQLQAPTQTDR-------DPNSPLTEDDEGVLVIKDEDQPVLHNAYEHANGGLLPSLP-------QDGAQLKSEDCDA-FPVAAVPLHHGHP-----LPNSHTSDQWKHGILEYKVPPSALAN---------------VEQSRPKEGQNQVVMVLPTLQQKP----VTSPEIP-----PER-VEPLKKEESCFNFNPLLYPRGNPGIMSPLAKKKMLSQVSGTGLLNNYPYGPPPPLVSRRLSSSGTEVSSAGQSSSQVSSSVETSIVIKRPSVIQHAQSFKSRGSEDRRSSTEGSQKDGCS----EGEP-----VHHSQTLIREPYLKRVDPHSSMEKSAEMPRP--GQAPSFLSEFYSSPHLHNLCRQTEHHLSKEQISKYLS--RDVYTRDSETAQGFPPSQHPDNVGLNFSARLSQKEKG-PPPERVTEEQPTDLSLPKSSPLKLPLSTSTLGGIPHAAIQQDIKNSPHFQAGNSQSSSVDYHPRACRVPPMTVSASKKVTESHSKVLEKTPNSRGEESMGFKIDEMSRPILSTKSSPQNICTARPLKRNIEDLENGPTEKKIRAVTPLHCSTQRDLPGKPRTPEADSESVKPAEPAVHINSYTSEGHKIPLHSHLFQGLYPGTFVSQVQDMCESLGSHVTPSYSHPLQYLKNQAVLSPLMPPFAIHSLMMQRQFLAA--NPAHMYRH-----QVGTSYGDILHPGLYPMSALHPQPAFSPPQLSSVHPSTKLS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P09547-1", "uniprot_id": "SWI1_YEAST", "id": "P09547-1", "name": "SWI/SNF chromatin-remodeling complex subunit SWI1", "aln": "MDFFNLNNNNNNNNTTTTTTTTNNNNTNNNNTNNNNNPANNTNNNNSTGHSSNTNNNTNNNNTNTGASGVDDFQNFFDPKPFDQNLDSNNNNSNSNNNDNNNSNTVASSTNFTSPTAVVNNAAPANVTGGKAANFIQNQSPQFNSPYDSNNSNTNLNSLSPQAILAKNSIIDSSNLPLQAQQQLYGGNNNNNSTGIANDNVITPHFITNVQSISQNSSSSTPNTNSNSTPNANQQFLPFNNSASNNGNLTSNQLISNYAASNSMDRSSSASNEFVPNTSDNNNNSNNHNMRNNSNNKTSNNNNVTAVPAATPANTNNSTSNANTVFSERAAMFAALQQKQQQRFQALQQQQQQQQNQQQQNQQPQQQQQQQQNPKFLQSQRQQQQRSILQSLNPALQEKISTELNNKQYELFMKSLIENCKKRNMPLQSIPEIGNRKINLFYLYMLVQKFGGADQVTRTQQWSMVAQRLQ-----ISDYQQLESIYFRILLPYERHMISQEGIKETQAKRIFLQQFLQELLKKVQQQQQAAALANANNNINSASSAPTPAAPGASVPATAAPGTEAGIVPVSANTPKSLNSNININVNNNNIGQQQVKKPRKQRVKKKTKKELELERKEREDFQKRQQKLLEDQQRQQKLLLETKLRQQYEIELKKLPKVYKRSIVRNYKPLINRLKHYNGYDINYISKIGEKIDSNKPIFLFAPELGAINLHALSMSLQSKNLGEINTALNTLLVTSADSNLKISLVKYPELLDSLAILGMNLLSNLSQNVVPYHRNTSDYYYEDAGSNQYYVTQHDKMVDKIFEKVNNNATLTPNDSNDEKVTILVDSLTGNQLPTPTPTEMEPDLDTECFISMQSTSPAVKQWDLLPEPIRFLPNQFPLKIHRTPYLTSLKKIKDEIDDPFTKINTRGAEDPKVLINDQLSTISMILRNISFSDNNSRIMSRNFYLKRFISDLLWLVLIHPENFTCNRKILNFKKDLVIVLSNISHLLEIASSIDCLLILILVISFGQPKLNPMASSSSFGSESLTFNEFQLQWGKYQTFGVDILAKLFSLEKPNLNYFKSILLNKNTGNNLYDRNSNNNHKDKKLLRRLLNLYNDN--NKNNNNRHNLLNDVVSFLFSAIPLQQVLSQSADPSLLIDQFSPVISQSLTSILVIVQKILPLS--NEVFEISENNSDSNSNNNGNKDSSFNFNKNLPFVWLSSEENIGSGLLKLSEIILNINNSTSKNTLLQQQNYSKVLLPSINISCVQLIKCLVEKSICFEN----CLNNDPEILKKIASIPNLFPTDLEIFQLFTNPSVDIQIINQYQLLYNLKNDILTNLE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:: . . .: : : :.:*.. .: :** *:. :* . :. :: *: .: : : .: * :: . :. .. ..:. .. : ... : . . : . .* :: .* *. : . :*:: ::. . .: : : : : . : . :: . : . : : . : : *: :* : *:*: *:: ** :* ::***: :: .**:** : :* :**. : :.* * . * *::*****. .:*. . * : ** *.: : . . . :.. . . : :. : : : . . .. . . . . . * : . . :. : :.: . : .: : :* : * : .: : .: : : . :..* : . ..: * . . . .:: . . .: . *:* * . .: . : : : : :. : : . . . : : :** . .: .* . * : : :. .. : . : : : . :. . .*:: : :. :. : . .:. : : : .. . :: : : : . .: :. : .* : .*. .: :.: :. : . . * : .: . . .... : . . :. : ** : . .: : : . : *: :. :*: ::. . * .: :: : .: :::: * :: : . . *:* ", "identical_positions": 67, "similar_positions": 320, "identity": "5.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-275", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LY89-1", "uniprot_id": "A0ABK0LY89_RAT", "id": "A0ABK0LY89-1", "name": "", "aln": "---------------------------------------------------------------------------MCFGPCPSSRGDRVSGPRAQSGVAFVPGAGARRALGLFPRHFPVTFQRGGQFRGGPCPRPLHKGPAQPPATALCQPRRCPFRATMRGVSCHLLLVLCFVPNLSGVGTQKASG----------CARWCPPNSECESNRSCKCKPGFNSSSPDGLITNPAQSCEDINECIQT----DNLCGPYAMCMNSEGSYYCVCNLGYKLLSGAESFTNKSENTCQASVDTGMIPVPSSIHTVPTAR-KLPEQPTTVHPRTQLGDSGERTPKDVNECTSGQNQCHQSTHCINKMGGYSCICRRGWKPAPGSP---NGPVNTVCEDVDECSSGQHQCHSSAICKNIPGSYKCRCPPGWIAIPRDKPN--NTVCQEPHFPTWTLLPTA----------------HSQALLSFSVEVQNLLRDFNPATVNYTIQKLIEAVDKLLEMPMDIGTQTQQV----ATQLLSNLEQSLRTLAQFLPKGPFTYKSPSNTELA-LMVKEQDNKDVTTV------------------HHSQAWMQLDWAVTAGAKSSENGYSVAGILSSPNIQKLLANTSLNLE-----------QKRDTLEDLYGSPVQSVTLTFLSNINAIFLTNTDTEKLASDVTFKFNLTSVKSLKA-------------REELMCAYWKSHDNGSGSWATDGC----SMNDTGFCHCNHLTSFAVLMAQYHVQ--------DPRLELITKVGLLLSLVCLLLCILTFLLVK--PIQSSRTMVHLHLCICLFLGSVIFLVGVENEGGEVGLRCRLVAMLLHFCFLAAFCWMALEGVELYF-----LVVRVFQGQGLSTWHRCLVGYGVPLLIVAIS-AAARMDGYGHATYCWLDFRKQGFLWSFSGPVAFIIFCNAAIFVITVWKLTKKFSE--INPNMKKLRKARVLTITAIAQLLVLGCTWGFGLFLFNPH------STWLSYIFTLLNCLQGLFLYVTLCLLNKKVREEYWKWACMVTG-NKYTEFTSSTTGTGTSQTRTLRPSESGM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0M6-1", "uniprot_id": "AGRE5_MOUSE", "id": "Q9Z0M6-1", "name": "Adhesion G protein-coupled receptor E5", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MRGVRCPGLLVVCILLSLSGAGTQKAESK--------NCAKWCPINSKCVSNRSCVCKPGFSSEKE--LITNPAESCEDINECLLP----GFSCGDFAMCKNSEGSYTCVCNLGYKLLSGAESFVNESENTCQASVNTGTTPVPSRIHTVTTAPGNLPEQTTTVH-QTQMGDSEERTPKDVNECISGQNHCHQSTHCINKLGGYSCICRQGWKPVPGSP---NGPVSTVCEDVDECSSGQHQCHNSTVCKNTVGSYKCHCRPGWKPTSGSLRGP-DTICQEPPFPTWTLLPTA----------------HSQTLLRFSVEVQNLLRDFNPATVNYTIQKLIEAVDKLLEDPMET--QTQQV----AAQLLSNLEQSLRTLAQFLPKGPFTYTSPSNTELS-LMVKEQDNKDVTTV------------------HHGQTWMELDWAVTAGAKISENGSSVAGILSSPNMEKLLGNTPLNLE-----------QRRASLEDFYGSPIPSVSLKLLSNINSVFLTNTNTEKLASNVTFKFDFTSVESIEP-------------RHELICAFWKAH-NGNGYWDTDGC----SMNGTGFCHCNHLTSFAILMAQYHVQ--------DPRLELITKVGLLLSLICLLLCILTFLLVK--PIQSSRTMVHLHLCICLFLGSIIFLVGVENEGGEVGLRCRLVAMMLHFCFLAAFCWMALEGVELYF-----LVVRVFQGQGLSTWQRCLIGYGVPLLIVAISMAVVKMDGYGHATYCWLDFRKQGFLWSFSGPVAFIIFCNAAIFVITVWKLTKKFSE--INPNMKKLRKARVLTITAIAQLLVLGCTWGFGLFLFNPH------STWLSYIFTLLNCLQGLFLYVMLCLLNKKVREEYWKWACMVTG-SKYTEFNSSTTGTGTSQTRALRSSESGM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48960-1", "uniprot_id": "AGRE5_HUMAN", "id": "P48960-1", "name": "Adhesion G protein-coupled receptor E5", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MGGR---VFLAFCVWLTLPGAETQDSRG----------CARWCPQNSSCVNATACRCNPGFSSFSE--IITTPTETCDDINECATPS---KVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN--PRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSP---NGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGV----------------HSQTLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELT-LMIQERGDKNVT-M------------------GQSSARMKLNWAVAAGAE--DPGPAVAGILSIQNMTTLLANASLNLHS----------KKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVE--------DWKLTLITRVGLALSLFCLLLCILTFLLVR--PIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYF-----LVVRVFQGQGLSTRWLCLIGYGVPLLIVGVS-AAIYSKGYGRPRYCWLDF-EQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSE--INPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDR------SLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9UHX3-1", "uniprot_id": "AGRE2_HUMAN", "id": "Q9UHX3-1", "name": "Adhesion G protein-coupled receptor E2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MGGRVFLVFLAFCVWLTLPGAETQDSRG----------CARWCPQDSSCVNATACRCNPGFSSFSE--IITTPMETCDDINECATLS---KVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQN--PRLCKSYGTCVNTLGSYTCQCLPGFKLKPEDPKLCTDVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSP---NGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGV----------------HSQTLSRFFDKVQDLGRDYKPGLANNTIQSILQALDELLEAPGDLETLPRLQQHCVASHLLDGLEDVLRGLSKNLSNGLLNFSYPAGTELS-LEVQKQVDRSVT-L------------------RQNQAVMQLDWNQAQKSG--DPGPSVVGLVSIPGMGKLLAEAPLVLEP----------EKQMLLHETHQGLLQDGSPILLSDVISAFLSNNDTQNLSSPVTFTFSHRSVIP----------------RQKVLCVFWEHGQNGCGHWATTGCSTIGTRDTSTICRCTHLSSFAVLMAHYDVQEE------DPVLTVITYMGLSVSLLCLLLAALTFLLCK--AIQNTSTSLHLQLSLCLFLAHLLFLVAIDQTGHKV--LCSIIAGTLHYLYLATLTWMLLEALYLFLTARNLTVVNYSSINRFMKKLMFPVGYGVPAVTVAIS-AASRPHLYGTPSRCWLQP-EKGFIWGFLGPVCAIFSVNLVLFLVTLWILKNRLSS--LNSEVSTLRNTRMLAFKATAQLFILGCTWCLGILQVGPA------ARVMAYLFTIINSLQGVFIFLVYCLLSQQVREQYGKWSKGIRKLKTESEMHTLSSSAKADTSKPSTVN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BY15-1", "uniprot_id": "AGRE3_HUMAN", "id": "Q9BY15-1", "name": "Adhesion G protein-coupled receptor E3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------MQGP--LLLPGLCFLLSLFGAVTQKTKT----------SCAKCPPNASCVNNTHCTCNHGYTSGSGQKLFTFPLETCNDINECTPPY---SVYCGFNAVCYNVEGSFYCQCVPGYRLHSGNEQFSNSNENTCQDTTSSKTT--------------------------------------------EGRKELQKIVDKFESLLTNQTLWRT--------------------EGRQEISS---------------------------------------------------------------------------------TATTILRDVES-----------KVLETALKDPEQK--------------VLKIQNDSVAIETQAITDN----CSEERKTFN-LNVQMN---------------------------------SMDIRCSDIIQGDTQGPSAIAFISYSSLGNIINAT------------------------FFEEMDKKDQVYLNSQVVSAAIGPKRNVSLSKSVTLTFQHVKMTPS---------------TKKVFCVYWKSTGQGSQ-WSRDGCFLIHVNKSHTMCNCSHLSSFAVLMALTSQEE-------DPVLTVITYVGLSVSLLCLLLAALTFLLCK--AIRNTSTSLHLQLSLCLFLAHLLFLVGIDRTEPKV--LCSIIAGALHYLYLAAFTWMLLEGVHLFLTARNLTVVNYSSINRLMKWIMFPVGYGVPAVTVAIS-AASWPHLYGTADRCWLHL-DQGFMWSFLGPVCAIFSANLVLFILVFWILKRKLSS--LNSEVSTIQNTRMLAFKATAQLFILGCTWCLGLLQVGPA------AQVMAYLFTIINSLQGFFIFLVYCLLSQQVQKQYQKWFREIVKSKSESETYTLSSKMGPDSKPSEGDVFPGQVKRKY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LLS8-1", "uniprot_id": "A0ABK0LLS8_RAT", "id": "A0ABK0LLS8-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MVLSSIRLLGILFGILFEGGFLSMLLIWSILQMMTIS--------ASCPQCNENAICFNSTHCICKEGFWTGSENRRIIEPHVKCQDIDECRLE----ETLCKDVSYCRNKIGTYICSCVVKYPIINWVAAIFDIDHPDCYVNKSNEIG-----------------------------------------------SKAACTSGVLYDCNSKEDVAKG----------------------------------------------------------------------------------------------------------ATVYLQNTER--------------------------------------------HILNENSDTPIKSSTRDIVYETNKCKKTTI-LEAGNN-------------------------------TMKINCTSVLKEN-KNRDETTVAFIAYKSLGNLLNGS------------------------FFRNKEGFQEVKLNSHIVSGAIRSEIKPVLSEPVILTLQNTQPIDS---------------RAEHLCVYWEGSEEGGS-WSTKGCSHVYTNKSYTICKCFHLSSFAVLVGLSNEENA-----VLSALSVITYVGLSLSLLCLFLAAITFLLCR--PIQNTSTTLHLQLSICLFLADLLFLIGINRTKPKV--LCSIIAGMLHYLYLASFMWMFLEGLHLFLTVRNLKVANYSHSGRFKKRLMYPVGYGFPALIVAVS-AIAGHKNYGTYNHCWLSL-HRGFIWSFLGPVAAIILINLVFYFQVLWILRSKLSS--LNKEVSTLQDTKIMTFKAIVQLFVLGCSWGIGLFIFFEVGKT--VRLIFAYLFTIINVLQGVLIFLVHCLLNRQVRMEYKKWFHRLQRETESESTELSHSTTHTKMGSSLKTENFCQTGNLHDSNPQNTRADVKCLPAVPVSCLLACCHDPEHDYPGLFL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5Y4N8-1", "uniprot_id": "AGRE1_RAT", "id": "Q5Y4N8-1", "name": "Adhesion G protein-coupled receptor E2", "aln": "-----------------------------------------------------------------MWGFWLLLFWGFSGTHRWGMTTLAILGQRLNGVNECQDTTTCPAYATCTDTTESYYCTCKQGFLPSNGQTNFQGPGVECQDVNECLRSDSPCGSNSVCTNIPGRARCSCLSGFSSSAGGSWILGSPGHFLCTDVDECLTIGICPKNSNCSNSVGSYSCTCQSGFVSNGSTCEDEDECVTR-----NACPEHATCHNTLGSYYCTCNEGLEFSGGGPMFQGLEESCEDVDECSRNSTLCGPSFICINTLGSYSCSCPAGFSLSTFQIPGHPADGNCTDIDECDDICPSNSSCTNTLGSYFCTCHPGFASSNGQLN--FTDQEVTCEDIDECTQDPFRCGRNSSCTNVPGSYNCSCLPDFRMDPGGSQAHGNFTCKRIPFKCKEDLIPKSEQIEQCQAGQGRNLDYTSFCTFVNATFTILDNTCENKSAPVSLQSAATSVSLMLEQASTWFEFSREETSTLGTILLETVESTMLAALLTPSGNASQTIRTEYLEIESKVINEECNEENVSI------------------NLKARGDKMDVGCFIIKESESTGTPGVAFVSFAHMDSVLDER------------------------FFEDGQASWKLRMNSHVVGGTVTGERKEDFSKPIVYTLQHIQPKQK---------------SERSICVSWNTDVEDGR-WTPSGCETVEASETHTVCSCNRMTNLAIIMASGELT-------MEFSLYIISYVGTVISLVCLALAIATFLLFR--AVQNHNTYLHLHLCVCLFLAKILFLTGIDKTDNQT--ACAIIAGFLHYLFLACFFWMLVEAVMLFLMVRNLKVVNYFSSRNIKMLHLCAFGYGLPVVVVIIS-ATVHPWGYGMHNRCWLNT-ETGFIWSFLGPVCMIITINSALLAWTLWVLRQKLCS--VNSEVSKLKDTRLLTFKAIAQIFILGCSWVLGIFQIGPL------ASIMAYLFTTINSLQGAFIFLIHCLLNRQVRDEYRKLLTRKTDLSSHSQTSGILLSSMPSTSKTG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61549-1", "uniprot_id": "AGRE1_MOUSE", "id": "Q61549-1", "name": "Adhesion G protein-coupled receptor E1", "aln": "-----------------------------------------------------------------MWGFWLLLFWGFSGMYRWGMTTLPTLGQTLGGVNECQDTTTCPAYATCTDTTDSYYCTCKRGFLSSNGQTNFQGPGVECQDVNECLQSDSPCGPNSVCTNILGRAKCSCLRGFSSSTGKDWILGSLDNFLCADVDECLTIGICPKYSNCSNSVGSYSCTCQPGFVLNGSICEDEDECVTR-----DVCPEHATCHNTLGSYYCTCNSGLESSGGGPMFQGLDESCEDVDECSRNSTLCGPTFICINTLGSYSCSCPAGFSLPTFQILGHPADGNCTDIDECDDTCPLNSSCTNTIGSYFCTCHPGFASSNGQLN--FKDLEVTCEDIDECTQDPLQCGLNSVCTNVPGSYICGCLPDFQMDPEGSQGYGNFNCKRILFKCKEDLILQSEQIQQCQAVQGRDLGYASFCTLVNATFTILDNTCENKSAPVSLQSAATSVSLVLEQATTWFELSKEETSTLGTILLETVESTMLAALLIPSGNASQMIQTEYLDIESKVINEECKE-NESI------------------NLAARGDKMNVGCFIIKESVSTGAPGVAFVSFAHMESVLNER------------------------FFEDGQSFRKLRMNSRVVGGTVTGEKKEDFSKPIIYTLQHIQPKQK---------------SERPICVSWNTDVEDGR-WTPSGCEIVEASETHTVCSCNRMANLAIIMASGELT-------MEFSLYIISHVGTVISLVCLALAIATFLLCR--AVQNHNTYMHLHLCVCLFLAKILFLTGIDKTDNQT--ACAIIAGFLHYLFLACFFWMLVEAVMLFLMVRNLKVVNYFSSRNIKMLHLCAFGYGLPVLVVIIS-ASVQPRGYGMHNRCWLNT-ETGFIWSFLGPVCMIITINSVLLAWTLWVLRQKLCS--VSSEVSKLKDTRLLTFKAIAQIFILGCSWVLGIFQIGPL------ASIMAYLFTIINSLQGAFIFLIHCLLNRQVRDEYKKLLTRKTDLSSHSQTSGILLSSMPSTSKMG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2B737-1", "uniprot_id": "A0A8M2B737_DANRE", "id": "A0A8M2B737-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------MELKWAFILGLFLPSCSGCALGYKFVKRKCVD----------EDECETPGMCGDAQCVNTDGSYYCTCAAGFKMSQTGPCKDINECLED----ELICPAQMRCENTFGSYVCVCPTGHQWKN---------EAECEDEDECLSS------------------------------------------------PCGLHRSCFNTPGSFVCKCSPGFRELEGG----------MCADINECSESPDVCGTNGDCINNPGGFSCRCHQGFTNYGNNQSKCIEMSCDQFKPEPDAGNTPEK---------------------LKHLMSLLMNSCKSLNDPHGEHFTAEKLLENLCNSTDDLLSEGNVADGETLSVFLDAVENSMRLIGPQLKDPVTKMETQN--TYAEVAVTRNQTPPSGSV------------------TLSTGSAHFNTSWETVVGKSYPGFAFVALVSYKDMNSSSDLFNSMAR------------------EKSDVKEKQITYKLNSKVVTAVVSNPDTKHLSKPVTLIFTHEEKRAESE-------------GVAYSCVYWSES---ERGWSGRGCELAWSNSTHTACSCSHLSSFAVLMALYPVED-------TFELVVITRVGLVLSLICLILCILTFRFCR--SIQGTRNSIHLHLSVCLFIADLVFLCGISSTHNQV--ACAIVAGLLHFFFLSAFCWMLLEGVQLYR------MVVLVFHTTLKHLYMYAVGYGVPLVIVSIS-AIAVPKGYGTDRHCWLSL-EGYLILSFFIPVCIIVILNITVFIITVWKLALKFSS--LNPDLSKLHKIRSFLATAVAQLCVLGGSWVFGFFLFQKNG-----TEVMLYLFIILNSLQGALIFIMHCLLSKQVRVEYRSLFMRMCSNKKKGDYSVSSTEPSHSSQKPLQIDQSTGESTI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7G7-4", "uniprot_id": "LPHN_DROME", "id": "A1Z7G7-4", "name": "Latrophilin Cirl", "aln": "MLPTILSISYEHISLDLSKYQTAYACEGKKLTIECDPGDVINLIRANYGRFSITICNDHGNVEWSVNCMFPKSLSVLNSRCAHKQSCGVLAATSMFGDPCPGTHKYLEAHYQCISAAQTSTTTNRPSPPPWVLSNGPPIFGNGSGLIHPPGVGAGAPPPPRLPTLPGVVGISGNPGLFNVPPQHTAVTHSTPSSSTTAVGGGRLKGGATSTTTTKHPAGRHDGLPPPPQLHHHHNHHGEDTASPTKPSSKLPAGGNATSPSNTRILTGVGGSGTDDGTLLTTKSSPNRPPGTAASGSVVPGNGSVVRTINNINLNAAGMSGGDDESKLFCGPTHARNLYWNMTRVGDVNVQPCPGGAAGIAKWRCVLMKRIPDSGYDEYDDDISSTTPAPSGGDCLHNSSSCEPPVSMAHKVNQRLRNFEPTWHPATPDLTQCRSLWLNNLEMRVNQRDSSLISIANDMSEVTSSKTLYGGDMLVTTKIIQTVSEKMMHDKETFPDQRQREAMIMELLHCVVKTGSNLLDESQLSSWLDLNPEDQMRVATSLLTGLEYNAFLLADTIIRERSVVQKVKNILLSVRVLETKTIQSSVVFPDSDQWPLSSDRIELPRAALIDNSEGGLVRIVFAAFDRLESILKPSYDHFDLKSSRSYVRNTAILSNDSDVNAGEIQQRLRILNSKVISASLGKGRHIQLSQPITLTLKHLKTENVTN----------------PTCVFWNYID---HAWSANGCSLESTNRTHSVCSCNHLTNFAILMDVVDEHQHSLFTMFDGNMRIFIYISIGICVVFIVIALLTLKLFNGVFVKSARTSIYTSIYLCLLAIELLFLLGIEQTETSI--FCGFITIFLHCAILSGTAWFCYEAFHSYSTLTS-DELLLEVDQTPKVNCYYLLSYGLSLSVVAIS-LVIDPSTYTQNDYCVLMEANALFYATFVIPVLVFFVAAIGYTFLSWIIMCRKSRTGLKTKEHTRLASVRFDIRCSFVFLLLLSAVWCSAYFYLRGAKMDDDTADVYGYCFICFNTLLGLYIFVFHCIQNEKIRREYRKYVRQHAWLPKCLRCSKTSISSGIVTGNGPTAGTLCSVSTSKKPKLPLGVSEEAHDDPQQQQQTPVPITEDAIMGATSDCELNEAQQRRTLKSGLMTGTLQAPPQTLGGHVVLERGSTLRSTGHASPTSSAGSTHLIFAHKQQQQQQQQGPLGESYYHQPDYYSWKQPSTGTGGLKTPREYYNNAGAAASSPQQAHEVFYWTQKPNSGHNGKKKRGAGGVPASPSGSLHSRTAAASQVLFYPSYKKTKPGQPTGYPQYAEALDPPLATGNAAAYYQQQQQLRRQQLHQQQQQQQQQQLSSDEEQAEQHAHLLHLQRRAGSQQQLPAPPPHMAQYQQEFMQRQYRNKHSNCDLGMGDAYYNQGSVGGADGGPVYEEILSNRNSDVQHYEVGDFDVDEVYNNSVGTGVFNNMRAAVAAGGSRYGGGSLSGGSVSSRSQQQQLKKQQQQQSLAQQRSARRCTADDDDDEDEEEDEEATAAEQLHDSVCDEDEEEDESDLEDDAHGLPPQSDERMRRLMAMQDEDFKRRFQRQLRKHGAPLDYGALPPGAGPQPEHNGAVFGVSGGVGEGSLRGAFRQQQQQALNAKSPGGRLAVNELFGHGNSGPPLPPANQTPAQKRQQLQKLSPQSTTSSSSHTSHSNPNPHPHQLTHPHPHQHPPHHQQRHLSAMLDENNTVRCYLEPLAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . .. : . . . . . :. . :: . : : : . * : : : . : : . *. *. * ** * * :::.:*::: : :: :. :.:. : :. *: : . ::. . :: : :**: :** .:. . * ::: ** *: *: *.. : ..**.. * :* * * * . : * ** :. : : . : . : . : : . : :*. * . : . * * :* * * ::: *: ..::: :* . ", "identical_positions": 39, "similar_positions": 113, "identity": "2.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-277", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48960-1", "uniprot_id": "AGRE5_HUMAN", "id": "P48960-1", "name": "Adhesion G protein-coupled receptor E5", "aln": "MGGR---VFLAFCVWLTLPGAETQ--DSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECQQNPRLCKSYGTCVNTLGSYTCQCLPGFKFIPEDPKVCT--DVNECTSGQNPCHSSTHCLNNVGSYQCRCRPGWQPIPGSPNGPNNTVCEDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISP-SNTELTLMIQERGDKNVTMGQS-SARMKLNWAVAAGAEDP--GPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQELLCAFWKSDSDRGGHWATEGCQVLGSKNGSTTCQCSHLSSFAILMAHYDVED-WKLTLITRVGLALSLFCLLLCILTFLLVRPIQGSRTTIHLHLCICLFVGSTIFLAGIENEGGQVGLRCRLVAGLLHYCFLAAFCWMSLEGLELYFLVVRVFQGQGLSTRWLCLIGYGVPLLIVGVSAAIYSKG-YGRPRYCWLDF-EQGFLWSFLGPVTFIILCNAVIFVTTVWKLTQKFSEINPDMKKLKKARALTITAIAQLFLLGCTWVFGLFIFDDR-SLVLTYVFTILNCLQGAFLYLLHCLLNKKVREEYRKWACLVAGGSKYSEFTSTTSGTGHNQTRALRASESGI---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z0M6-1", "uniprot_id": "AGRE5_MOUSE", "id": "Q9Z0M6-1", "name": "Adhesion G protein-coupled receptor E5", "aln": "MRGVRCPGLLVVCILLSLSGAGTQKAESKNCAKWCPINSKCVSNRSCVCKPGFSSEKELITNPAESCEDINECLLPG-FSCGDFAMCKNSEGSYTCVCNLGYKLLSGAESFVNESENTCQASVNTGTTPVPSRIH-TVTTAPGNLPEQTTTVHQTQMGDSEERTPKDVNECISGQNHCHQSTHCINKLGGYSCICRQGWKPVPGSPNGPVSTVCEDVDECSSGQHQCHNSTVCKNTVGSYKCHCRPGWKPTSGSLRGP-DTICQEPPFPTWTLLPTAHSQTLLRFSVEVQNLLRDFNPATVNYTIQKLIEAVDKLLEDP------METQTQQVAAQLLSNLEQSLRTLAQFLPKGPFTYTSP-SNTELSLMVKEQDNKDVTTVHHGQTWMELDWAVTAGAKISENGSSVAGILSSPNMEKLLGNTPLNLE-QRRASLEDFYGSPIPSVSLKLLSNINSVFLTNTNTEKLASNVTFKFDFTSVES-------------IEPRHELICAFWKAHNG-NGYWDTDGC----SMNGTGFCHCNHLTSFAILMAQYHVQD-PRLELITKVGLLLSLICLLLCILTFLLVKPIQSSRTMVHLHLCICLFLGSIIFLVGVENEGGEVGLRCRLVAMMLHFCFLAAFCWMALEGVELYFLVVRVFQGQGLSTWQRCLIGYGVPLLIVAISMAVVKMDGYGHATYCWLDFRKQGFLWSFSGPVAFIIFCNAAIFVITVWKLTKKFSEINPNMKKLRKARVLTITAIAQLLVLGCTWGFGLFLFNPH-STWLSYIFTLLNCLQGLFLYVMLCLLNKKVREEYWKWACMVTG-SKYTEFNSSTTGTGTSQTRALRSSESGM---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "R4GDT3-1", "uniprot_id": "R4GDT3_DANRE", "id": "R4GDT3-1", "name": "", "aln": "------------------------------------------------MEPKWALLLGFILSFRSFTTEGSSYTSDKGLSSVIPAVCHG------VQCNNGPTTASADPDLEISGDTDSEISGDSDLEISSQPYLTMSTQASLDITASSFPAHRQDVIRATQTS-------------------------------ETTSQNAFVSPKGAAEQTEIECDQFKSKPDEDHTPEKLNQMMSLLKDSCESLNDP--------------------------------------------VEKHFNAEELLENLCNSTDDLLLEG-------KVADGENLSVFLDMVENSMRLIGPQLKDPVTKMETQNTYAEVALTRNQTPPSGSVTLSTDSALFSTSWETVVGKAYS--GFAFVALFSYKDMNSSSDLSHKTSRTLQEDSRKRLHVDEKK-ITYQLNSKVVTAVVSNPDTKKLSDLMMLTFTHEEERAE-------------SGGVAYTCVYWNESEK---VWSGRGCVKEWSNSTHTVCHWSHLSSFAVLMALYPVQDTFASVLITRVGLVLSLLCLFLCILTFRFCRSIQGTRNSIHLHLSVCLFIADLVFLCGISSTHN--QVACAIVAGLLHFFFLSAFCWMLLEGVQLYRMVVLVFHTT-LKHLYLYAVGYGVPLVIVSISAITFPKG-YGTNKHCWLSL-EGYLILSFFAPVCIIVILNIIVFIITVWKLALKFSSLNPDLSKLHKIRSFLATAVAQLCVLGGSWVFGFFLFQKNGTEVMLYLFIILNSLQGALIFIMHCLLSKQVRVEYHSLFVRMCPYKKKGDYSVSTEPSHSSQKRLQSDQSTGESQL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :: :* . . : .. .*. : * . *. * *. : ..:. .: : . : . . . . .: . : . : **:*. . . : *: .* .: ... : :. . *.. .* : ..: :::: : .*.*: : :*. :*: :* :. * . . : : :*::* :: .. . .: :. .* ...* . * :...::* :* . : . . :. . : :: . : : * : : .::: :*::* . : : * . . *.:*: . * ** * . *: .**:***:*** * *:* ***:*** ***:**:****** : :.**.:*. :****.:***:.. :** *:.. . : * :** :**: **:***** ***::** :** **: *. :******:**.:* . ** :***.: : :: ** .** :*:: * :*: *****: ***.:**::.**:* * : **:*** :** :* **:*:*: . : : *:* :**.*** ::::: ***.*:** ** . : .* ::. :* : .*.* ..:* ", "identical_positions": 168, "similar_positions": 226, "identity": "19.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-287", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WV91-1", "uniprot_id": "FPRP_MOUSE", "id": "Q9WV91-1", "name": "Prostaglandin F2 receptor negative regulator", "aln": "MGRPAPRPLLLALLSLAVCRGRVVRVPAGTLVRVVGTELVIPCNVSDYDGPSEQNFDWSFSSSGSSFVELASTWEVGFPAQLYRERLQRGDILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADALVVGPSSRPPPGLSLREGEPFELRCIASTTSPLHTHLALRWELH-RGPVHRSILALSHEGRFHPGPGYEQRYHSGDVRLDTVGSDAYRLSVARALSADQGSYRCVVSEWITEQGSWQEIQEKAVEVATVVIQPTA--LQLAVPRTVSVTEGKDLDLSCNITTDRVDDVRPEVTWYFKKTPDTSLLASHMLARLDRDSLVHSSP--HVALSHVDTRSYHLLVRDVSKENSGYYLCLVALWAPGHNRSWHKVAEAMSAPSGVSVTWLEPEYQVYLNASKVPGFSDDPTELQCRVIDTKRLEAGVRLTVSWYYRMTRRNDDVVASELLAVMDGDWTLRYGERSKQRAQDGEFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTRQRNNSWVKSKDVFSKPVNIFWASEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKS-PRYSVLITAEKPVGDLSSPNETKYIISLDQDSVVKLENWTDASRVDGVVLEKVQEDEFRYRMYQTQVSDAGLYRCMVTAWSPIGGSLWREAATSLSNPIEIDFQTSGPTFNASVHSDTPSVTRGDLIKLFCIVTVEGAVLDPDDMAFDVSWFAVHSFGLDKAPVLLSSLDRKGVVTTGQRDWKSTVSLERVSVLEFLLQVHGSEDQDFGNYYCSVTPWVRSPT-GSWQREAEIHSRPIFITVKMDVLNAFKYPLLIGVGLSTVIGLLSCLIGYCSSHWCCKKEVRETRRERRRLMSMEMD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2B2-1", "uniprot_id": "FPRP_HUMAN", "id": "Q9P2B2-1", "name": "Prostaglandin F2 receptor negative regulator", "aln": "MGRLASRPLLLALLSLALCRGRVVRVPTATLVRVVGTELVIPCNVSDYDGPSEQNFDWSFSSLGSSFVELASTWEVGFPAQLYQERLQRGEILLRRTANDAVELHIKNVQPSDQGHYKCSTPSTDATVQGNYEDTVQVKVLADSLHVGPSARPPPSLSLREGEPFELRCTAASASPLHTHLALLWEVH-RGPARRSVLALTHEGRFHPGLGYEQRYHSGDVRLDTVGSDAYRLSVSRALSADQGSYRCIVSEWIAEQGNWQEIQEKAVEVATVVIQPSV--LRAAVPKNVSVAEGKELDLTCNITTDRADDVRPEVTWSFSRMPDSTLPGSRVLARLDRDSLVHSSP--HVALSHVDARSYHLLVRDVSKENSGYYYCHVSLWAPGHNRSWHKVAEAVSSPAGVGVTWLEPDYQVYLNASKVPGFADDPTELACRVVDTKSGEANVRFTVSWYYRMNRRSDNVVTSELLAVMDGDWTLKYGERSKQRAQDGDFIFSKEHTDTFNFRIQRTTEEDRGNYYCVVSAWTKQRNNSWVKSKDVFSKPVNIFWALEDSVLVVKARQPKPFFAAGNTFEMTCKVSSKNIKS-PRYSVLIMAEKPVGDLSSPNETKYIISLDQDSVVKLENWTDASRVDGVVLEKVQEDEFRYRMYQTQVSDAGLYRCMVTAWSPVRGSLWREAATSLSNPIEIDFQTSGPIFNASVHSDTPSVIRGDLIKLFCIITVEGAALDPDDMAFDVSWFAVHSFGLDKAPVLLSSLDRKGIVTTSRRDWKSDLSLERVSVLEFLLQVHGSEDQDFGNYYCSVTPWVKSPT-GSWQKEAEIHSKPVFITVKMDVLNAFKYPLLIGVGLSTVIGLLSCLIGYCSSHWCCKKEVQETRRERRRLMSMEMD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QAI9-1", "uniprot_id": "F1QAI9_DANRE", "id": "F1QAI9-1", "name": "", "aln": "MG--MTRVLILLYAAVGLCSCRSVSVSGGPLLRVEGQPLSIRCDVSDYEGPREQDFEWTVTR-ETKTINVISTFDPAFSDRSLQDRIKTGDISIARLADNVVELRIQEAQISDSATYRCSTPSTDSVISGNYEASVQLQVVPNTLIVAPD---PPTPVVPEGGSIRLQCSVSRSFIPGIFLSITWSVKNRSSLLEDLLTFGPDMSVTVDTVSSQRYTDGGMRLEMGNGVSHSLVLSGVTPADQGLYMCTASLWTREQGIWSRIQEKSMEMGDVTVTPAVNSLAVHVQNDSTLSTGDSLVLLCSVMVSGASAVDLDVTWLQN--------DTHVLGHLSRDGVQTDSSSRAVDVKRLGKWDYQLKIQDVETSDGGLYTCKVNVWIQRDTGRWYKAAEKISDPVRVHVIKHNPEYTAVLSSSVTAKFSGDPTELECKVMNVSNLRS-GRLGVSWLYRDLQPNGTPGSTQTVASLDENGTLVPGRAFKSRVEAGLITATRAEPSMFKLRLLHTTDADAGEYMCVVSAWIPSPHGHWKKVAEHLTPAVKVSFANKRPVLGVVARRLREATAVGSTFEMSCQASVQNLPSGSAFSISVLSEESVGASG-----RRRASLDPDLLLKLEDVGEPARSHSLMLLKTKKTEFEFRIPAVRLSDRGFYYCEMKAWTRQIGDEWVEVAKGLSNKVQIAFTHKGPTFDVSISSDVSSVFPWETVKMECDVSVSGTSPSADDVAYELKWFLSR-LRGSSSPTLLASMDRWGVVRKSPRNDSSDCSLERLEARRFALSVHNTQDSDAGDYHCSVTPWVRSSVNGVWSRAAEISSQRVFLNVRFALWSSMKLPLLYGICASATVGVVSLILGLVCAHCCCKTSTPATPRSRK-LMELEMD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .* *:* ::.:* * * *. ..*:** * * * *:****:** **:*:*:.: :. ::: **:: .*. : ::*:: *:* : * *::.***:*::.* **.. *:*******:.:.**** :**::*:.::* *.*. ** : ** .:.*:* .: : .*:: *.:: *.. ..:*:: : . . .*** .*.:**: .. :: * :: . .**** * * .* * *** *..****::*:. *.: *:. * * . ::: *..* * *.: .. .. * :*** . :::*.:*.**.: .*. * :.::. .*:* ::**...:.* * * * :* .. *:*.** :* * * * :*:* . *.:* .. *:.***** *:*::.. .: *: *** ** : .. ::: :* :* : ** *. *.*.: * : :: ... *::*: :**: * *:* ****** . :. * * : :: .*:: :* : .** * **: : *.*.****:*:.* :*: * . :*: : :*:.** . : *** * ::***: :.:* ..::* *.:: **.:*: .::** *:* * :.**: *. * *.*..*** ::* * .** *:.*: **..** : :*: * ::*.*: ..**:*:::.** : : ..:*.**:*:** *:* .. *: .* ****:.. .* *.**.::*.* *:*:*******:*.. * *.: *** *: :*:.*:: : .::* *** *: *:.:*::* ::* .:* ***... * *.*: **.:***", "identical_positions": 295, "similar_positions": 325, "identity": "33.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-289", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91VP7-1", "uniprot_id": "TM101_MOUSE", "id": "Q91VP7-1", "name": "Transmembrane protein 101", "aln": "MASKIGSRRWMLQLIMQLGSVLLTRCPFWGCFSQLMLYAERAEARRKPDIPVPYLYFDMGAAVLCASFMSFGVKRRWFALGAALQLAISTYTAYIGGYVHYGDWLKVRMYSRTVAIIGGFLVLASGAGELYRRKPRSRSLQSTGQVFLGIYLICVAYSLQHSKEDRLAYLNHLPGGELMVQLFFVLYGVLALAFLSGYYVTLAAQILAVLLPPVMLLIDGNVSYWHNTRRVEFWNQMKLLGESVGIFGAAVILATDG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96IK0-1", "uniprot_id": "TM101_HUMAN", "id": "Q96IK0-1", "name": "Transmembrane protein 101", "aln": "MASKIGSRRWMLQLIMQLGSVLLTRCPFWGCFSQLMLYAERAEARRKPDIPVPYLYFDMGAAVLCASFMSFGVKRRWFALGAALQLAISTYAAYIGGYVHYGDWLKVRMYSRTVAIIGGFLVLASGAGELYRRKPRSRSLQSTGQVFLGIYLICVAYSLQHSKEDRLAYLNHLPGGELMIQLFFVLYGILALAFLSGYYVTLAAQILAVLLPPVMLLIDGNVAYWHNTRRVEFWNQMKLLGESVGIFGTAVILATDG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8PYE5-1", "uniprot_id": "A0A2R8PYE5_DANRE", "id": "A0A2R8PYE5-1", "name": "", "aln": "MAAAT--RKKALRFFSQFGAFILTRFGFWNCFAMLMLFAERADVKRKPDIQVPYLYIDLGAAVLCASFMSFGVKRRWFALAAAIHLALSTYVSYVGGQVHYGDWLKVRMYSRAMAIIGGFLILSSGAGEVYRQKPRTRSLQSTGQVFLGIYLICMVYSLQHSKEDRLAYLDHIPGGELTVQLLVLVFGVLALAYLSGCYVRVASQILAVLLPLVILFIDGNFGYWHRSCRVEFWNQMKLIGQNVGIFGAVLILATDS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: *: *::: *:*:.:*** **.**: ***:****:.:***** *****:*:*********************.**::**:***.:*:** **************::*******:*:*****:**:***:*****************:.**************:*:***** :**:.:::*:****:*** ** :*:******** *:*:****..***.: **********:*:.*****:.:*****.", "identical_positions": 182, "similar_positions": 58, "identity": "70.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-29", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M918-1", "uniprot_id": "F1M918_RAT", "id": "F1M918-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------MKTEDEEMEDQLSK------------------------------------------------------------------------------------------EEIVSEDKEFD----YRTIIKENFFIIWDKTSLLGESATLNCVTTHKDQK-------------------------------LLEHIFDVNIQTSKSP-------QTVVLYGAAGIGKTTLLKKAVLEWADGNLYQQ-FTHVFYLSGREIS-QEKEKNFAQLISKHWPSSEGPIEQILCKPSSLLFILDSFDELDFSFEEPEFA----LCRDWTQKHPVSFLISSLLRKVMLPESYLLVTTRTTAWKRLVPLLQKPHRVKLPGLSRSSRIDYIHHLLKDKTWAMNAVCSIRMNAKLFNMCHVCHVCQMICTFLKEQVEKGGNVEMTCQTSTALFTYYICSLFPRIAGS--SVTLPNETLLRSLCQAAVEGIWTMKHVLYQQNLRKHELTREDLSLFLEANVLQQDTEC----ENCYTFTHLQVQEYFAALFYLLRENPE------EKDHPLEPFENVHLLLES--NHFHDPHLEQMKCFLFGLLNKDRVQQLEETFNLTISRAVREELLVCLEALEKDDSPLSQLRIQDLLHCIYETQDEEFITQALTYFQKIMVK-VDEESKLLIYSYCLKHCHSLQTVRLTARADLRNMLDPTAEICLED--------AAVRIIHYWQDLFSVLHTNESLLEMDLYESRLDESLMKILNEEFSHPKCNLQKVMFRAVCFLNSCYDFS-FLAFNNTVTHLDLKDTDLGDNGVKTLCEALKYQGCKLRVLRLESCDLNVTHCQNLSKALQSNRSLVFLNLSTNSLSNDGVKSLCEVLENPNCPLERLALASCGLTKVGCEVLSSALTK-TKRLTHLCLAHNVLEDEGIELLSYTLRHPRCTLQSLVLRCCYFTPIGSEHLSTALQNN-KSLIHLDLGFNKLADSGVKLLCQTLQQPNCNLQELELMGCVLTSEACGDLASVLVNN-SNLWNLDLGNNILDDAGLNILCEALRNPNCQIRRLGLENCGLTPGCCQDLLDLLSNNQS--VIQMNLMKNSLDYEAIRNLCKVLRSPTCKMEFLALDKKDLFKKKIKKFLVDVRINNPHLVIRPQCP--NTESGCWWQYF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6B966-1", "uniprot_id": "NAL14_MOUSE", "id": "Q6B966-1", "name": "NACHT, LRR and PYD domains-containing protein 14", "aln": "------------------------------------------------------------------------------------------------------------MKTEDDEMEYEASK------------------------------------------------------------------------------------------EETVSEDKDFDDGIDYRTVIKENIFTMWYKTSLHGEFATLNCVITPKDQN-------------------------------LLQHIFDEDIQTSEAP-------QTVVLQGAAGIGKTTLLKKAVLEWADGNLYQQ-FTHVFYLNGKEIS-QVKEKSFAQLISKHWPSSEGPIEQVLSKPSSLLFIIDSFDELDFSFEEPQFA----LCKDWTQISPVSFLISSLLRKVMLPESYLLVATRSTAWKRLVPLLQKPQRVKLSGLSKNARMDYIHHLLKDKAWATSAIYSLRMNWRLFHMCHVCHMCQMICAVLKGQVEKGGRVEETCKTSTALFTYYICSLFPRIPVG--CVTLPNETLLRSLCKAAVEGIWTMKHVLYQQNLRKHELTREDILLFLDAKVLQQDTEY----ENCYMFTHLHVQEFFAALFYLLRENLE------EQDYPSEPFENLYLLLES--NHIHDPHLEQMKCFLFGLLNKDRVRQLEETFNLTISMEVREELLACLEGLEKDDSSLSQLRFQDLLHCIYETQDQEFITQALMYFQKIIVR-VDEEPQLRIYSFCLKHCHTLKTMRLTARADLKNMLD-TAEMCLEG--------AAVQVIHYWQDLFSVLHTNESLIEMDLYESRLDESLMKILNEELSHPKCKLQKLIFRAVDFLNGCQDFT-FLASNKKVTHLDLKETDLGVNGLKTLCEALKCKGCKLRVLRLASCDLNVARCQKLSNALQTNRSLVFLNLSLNNLSNDGVKSLCEVLENPNSSLERLALASCGLTKAGCKVLSSALTK-SKRLTHLCLSDNVLEDEGIKLLSHTLKHPQCTLQSLVLRSCSFTPIGSEHLSTALLHN-RSLVHLDLGQNKLADNGVKLLCHSLQQPHCNLQELELMSCVLTSKACGDLASVLVNN-SNLWSLDLGHNILDDAGLNILCDALRNPNCHVQRLGLENCGLTPGCCQDLLGILSNNKS--VIQMNLMKNALDHESIKNLCKVLRSPTCKMEFLALDKKEILKKKIKKFLVDVRINNPHLVIGPECP--NTESGCWWNYF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86W24-1", "uniprot_id": "NAL14_HUMAN", "id": "Q86W24-1", "name": "NACHT, LRR and PYD domains-containing protein 14", "aln": "--------------------------------------------------MADSSSSSFFPDFGLLLYLEELNKEELNTFKLFLKE-------TMEPEHGLTP-WNEVKKARREDLANLMKKYYPGEKAWSVSLKIFGKMNLKDLCERAKEEINW--------------------------------------------SAQTIGPDDAKAGETQEDQEAVLGDGTEYRNRIKEKFCITWDKKSLAGKPEDFHHGIAEKDRK-------------------------------LLEHLFDVDVKTGAQP-------QIVVLQGAAGVGKTTLVRKAMLDWAEGSLYQQRFKYVFYLNGREIN-QLKERSFAQLISKDWPSTEGPIEEIMYQPSSLLFIIDSFDELNFAFEEPEFA----LCEDWTQEHPVSFLMSSLLRKVMLPEASLLVTTRLTTSKRLKQLLKNHHYVELLGMSEDAREEYIYQFFEDKRWAMKVFSSLKSNEMLFSMCQVPLVCWAACTCLKQQMEKGGDVTLTCQTTTALFTCYISSLFTPVDGG--SPSLPNQAQLRRLCQVAAKGIWTMTYVFYRENLRRLGLTQSDVSSFMDSNIIQKDAEY----ENCYVFTHLHVQEFFAAMFYMLKGSWE------AGNPSCQPFEDLKSLLQS--TSYKDPHLTQMKCFLFGLLNEDRVKQLERTFNCKMSLKIKSKLLQCMEVLGNSDYSPSQLGFLELFHCLYETQDKAFISQAMRCFPKVAIN-ICEKIHLLVSSFCLKHCRCLRTIRLSVTVVFEKKILKTSLPTNTW--------DGDRITHCWQDLCSVLHTNEHLRELDLYHSNLDKSAMNILHHELRHPNCKLQKLLLKFITFPDGCQDISTSLIHNKNLMHLDLKGSDIGDNGVKSLCEALKHPECKLQTLRLESCNLTVFCCLNISNALIRSQSLIFLNLSTNNLLDDGVQLLCEALRHPKCYLERLSLESCGLTEAGCEYLSLALIS-NKRLTHLCLADNVLGDGGVKLMSDALQHAQCTLKSLVLRRCHFTSLSSEYLSTSLLHN-KSLTHLDLGSNWLQDNGVKLLCDVFRHPSCNLQDLELMGCVLTNACCLDLASVILNN-PNLRSLDLGNNDLQDDGVKILCDALRYPNCNIQRLGLEYCGLTSLCCQDLSSALICNKR--LIKMNLTQNTLGYEGIVKLYKVLKSPKCKLQVLGLCK-EAFDEEAQKLLEAVGVSNPHLIIKPDCNYHNEEDVSWWWCF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3TKR3-1", "uniprot_id": "NAL4C_MOUSE", "id": "Q3TKR3-1", "name": "NACHT, LRR and PYD domains-containing protein 4C", "aln": "-------------------------------------------------------MASFFSDFGLMWYLEELNKKEFMKFKEFLKQ-------EILQLRLKQISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRKD--------------------------------------------------------------------LMERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKVQDFSKQKFTQDDYD-------------------------------RFENFLIS-KVTAKKP-------HMVFLQGAAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVK-KMKRASLAELISKEWPKTSAPIEDILSQPEKLLFVIDNLEVMECDMSERESE----LCDTCTEKQPVRILLSSLLRRKMLPKSSFLISATPETFEKMEGRVECTNVKIVTGFNESNIKMYFRSLFQDKTKTQEIFSLVKENQQLFTVCQVPVLCWMVATCLKKEIEKGRDLVSVCRRTTSLYTTHIFNLFIPQSAQ--YPSKESQAQLQSLCSLAAEGMWTDTFVFGEEALRRNGIMDSDIPTLLDVRILEKSKKS----EKSYIFLHPSIQEVCAAIFYLLKSH---------MDHPSQDVKSIEALIFT-FLKKVKVQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNEELQEQVDGMKLFYCLFEMDDEAFLAQAMNCMEQINFV-AKDYSDVIVAAHCLQHCSTLKKLSLSTQNVLS------EGQEHS---------YTEKLLMCWHHMCSVLISSKDIYILQVKNTNLNETASLVLYSHLMYPSCTLKALVVNNVTFLCDNRLFFELIQNQ----------------------------------------------------------CLQHLDLNLTFLSHGDVKLLCDVLSQEECNIEKLMVAACNLSPDDCKVFASVLIS-SKMLKHLNLSSNNL-DKGISSLSKALCHPDCVLKNLVLVNCSLSEQCWDYLSEVLRRN-KTLNHLDISSNDLKDEGLKVLCGALSLPDSVLKSLSVRYCLITTSGCQDLAEVLRKN-QNLRNLQVSNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASAFTHCKT--LWGINLQENALDHSGLIVLFEALKQQQCTLHVLGLRI-TDFDKETQELLMAEEEKNPHLSILSSV---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66X19-1", "uniprot_id": "NAL4E_MOUSE", "id": "Q66X19-1", "name": "NACHT, LRR and PYD domains-containing protein 4E", "aln": "-------------------------------------------------------MASFFSDFGLMWYLEELNKKEFMKFKELLQQ-------EILQLGLKHISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRQD--------------------------------------------------------------------LMERAGREIAGHSKLYQVHLKKKLTHDYARKFNIKDQDSLKQKFTQDDCD-------------------------------HFENLLIS-KATGKKP-------HMVFLQGVAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVK-KMKRASLAELISKEWPNASAPIEEILSQPEKLLFVIDNLEVMECDMSEWESE----LCDDCMEKQPVNILMSSLLRRKMLPESSFLVSATPETFEKIEDRIECTNVKMMAGFNESSIKVYFYSLFQDRNRTQEIFSLVRENEQLFSVCQVPVLCWMVATCLKKEIEKGRDPVSICRRITSLYTTYIFNLFIPHSAQ--YPSKKSQDQLQGLCSLAAEGMWTDTFVFAEEALRRNGIMDSDISTLLDVRILEKSKES----EKSYIFLHPSIQEVCAAIFHLLKSH---------VDHPSQDVKSIEALIFT-FLKKVKIQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNKELQEQIDGMKLFYCLFEMDDEAFLPQVMNCMEQIKFV-AKDYSDVIVAAHCLQHCSTLKKLSLSTQNILS------EGQEHS---------YTEKLLICWHHVCSVLTSSKDIHVLQVKDTNFNERAFLVLYSHLKYPSCILKVLEVNNVTLLCDNRLLFELIQNQ----------------------------------------------------------RLQLLNLSLTFLSHNDVKLLCDVLNQAECNIEKLMVADCNLSPDDCKVFVSVLIS-SKMLKHLNLSSNNL-DKGISSLSKALCHPDCVLKNLVLAKCSLSEECWHYLSEVLRRN-KTLTHLDISFNDLKDEGLKVLCGALTLPDSVLISLSVRYCLITTSGCQDLAEVLRNN-QNLRNLQISNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASSFTHCKT--LLGINLQENALDHSGLVALFEAMKQQQCTVNLRGLRI-TDFDKETQEFLMAEKEKNPYLSI-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZP31-1", "uniprot_id": "D3ZP31_RAT", "id": "D3ZP31-1", "name": "", "aln": "-------------------------------------------------------MASFFSDFGLMWYLEELNKKEFVKFKEFLKQ-------EILQLRLKQISWTKVKKASREDLANLLLKHYEEKQAWDMTFKIFQKMNRKD--------------------------------------------------------------------LIERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKAQDLFKQKFTQDDCD-------------------------------RFENLLVS-KATGKKP-------HMVFLQGVAGIGKSLMLTKLMLAWSEGIVFQNKFSYIFYFCCQDVK-QLKRASLAELISREWPNASAPTAEILSQPEKLLFIIDSLEVMECNMSERESE----LCDNCTEKQPVSLLLSSLLRRKMLPESSFLISATPETFEKMEDRIECTNVKIITGFNENNIKMYFRSLFQDKNRTLEAFSLVRENEQLFNVCQVPVLCWMVATCIKKEIEKGRDPVFICRRTTSLYTTHIFNLFTPQNAQ--YPSKKSQDQLQGLCSLAAEGMWTDTFVFSEEALRRNGILDSDIPTLLDRRILERSKES----ESCYIFLHPSLQEVCAAVFYLLKSH---------LDHPSQDVKSVEALLFT-FLKKAKVQWIFLGCFLFGLLHESEQEKLEMFFGHQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEAFLMQAMNCMEQINFV-AKDYSDVIVAAYCLKHCSTLKKLSFSTQNILS------EEQEHS---------YTEKLLICWHHMCSVLISSKDIHVLQVKDTNLNETAFWVLYNHLKYPSCTLKVLVVNNVTFLCDNHLFFELIQNQ----------------------------------------------------------RLQHLNLSLTFLSHSDVKLLCDVLNQAECNIEKLMIAACNLSPDDCKVFASVLIS-SKMLKHLNLSSNNL-DKGISSLCKALCHPDCILKHLVLANCSLSEQCWDYLSEVVRRN-KTLSHLDISSNDLKDEGLKVLCGALTLPDSGLISLSVRHCLITTSGCQDLAEVLRHN-QNLRSLQVSNNKIEDAGVKLLCDAIKQPNCHLENIGLEACELTGACCKDLASAFVHCKT--LWGINLLENALDHSGLVVLFEALKQQKCTLHVLGLRI-TDFDKETQEFLIAEEEKNPYLSILSNV---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZUH1-1", "uniprot_id": "D3ZUH1_RAT", "id": "D3ZUH1-1", "name": "", "aln": "-------------------------------------------------------MASFFSDFGLMWYLEELNKKEFMKFKEFLKQ-------EILQLGLKQVSWTEVKKASREDLASLLLKHYEEKQAWDMTFNFFQKINRKD--------------------------------------------------------------------LIKRAKREIDGYPKLYRAHLKTKLTHDSSRIFNINIQDFLKEKFTKDDHD-------------------------------RFETLLQS-KGTESKP-------QVVVLSGVAGIGKTLMLKRLMLAWIEGLVFPYKFSYIFYFCCQEVK-QLKTASLAELISREWPDPSAPIEEILSEPEKLLFIIDSLEGIECDLFKCDSE----LCDNCMEKQPVNILLSSLLRKKMLLEASLLISTTPETFEKMEDRIEYTHVKIITGLNESDIKMCFHRLFQDRNRAQEAFSLVRENEQMLTICQVPVLCWMVATCLKTEIEKGRNLVSTCRRTTSLYTTYIFNLFIPQSAH--SPSKKSQDQLQGLCSLAAEGIWTDTFVFTEEALRRNGILDSDIPTLLDIGMLGKMGKF----ENCYIFLHPSLQEACAAIFYLLKSH---------GDHPIEDVKSVEALLFT-FLKKAKVQWILGGRFIFGLLHESEQKKLEAFFGHQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEDFLMEAMNYMEQINFV-AKDYSDVIVAAYCLKHCYTLKKLSFSTQNILN------EEHEHS---------CMENLLTCWRHICSVLINSKDIQELQIKDTNLNEPAFSVLYNSLKYCNDTLKVLVENNVFFLCEKYLFFELIQNC----------------------------------------------------------NLQHLNLNLTFLSHSDVKLLCDVLNQAECNIEKLEVAACNLSPDDCKMFASILMS-SKTLKQLNLSSNIL-GKGISSLCKSLCHPDCILEHLVLAKCSLSDQCWDYLSDGIRQN-KTLNHLDISSNDLKDEGLKVLCRALALPNSVLKSLCLRHCLITTSGCQDLAEVLRNN-QNLTSLQISYNKIEDAGVKLLCDAIKQPNCHLEDLGLEACELTGACCEDLASTFTQCRT--LWGINLLNNTLDYTGLVVLCEALRQQKCTPHVLGLRI-TDFDNETQAFLVAEQEKNPDLSILSGV---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BU40-1", "uniprot_id": "NAL4A_MOUSE", "id": "Q8BU40-1", "name": "NACHT, LRR and PYD domains-containing protein 4A", "aln": "-------------------------------------------------------MASFFSDFGLMWYLEELNKKEFVKFKEFLKQ-------EVLQLGLKQVSWTEVKKASRQDLASLLLKHYEEKPAWDMTFRFFQKINRKD--------------------------------------------------------------------LIERAKREIDGCPKLYRAHMKTKMTHDSSRAFTISIQNFLKEKFTEDDYD-------------------------------CFENLFQS-KGTESKP-------QVVFLSGGAGVGKTLMLKRLMLAWIESPVFLHKFSYIFYFCCREVK-QLKTASLAELISREWPGPSAPIEEILSKPEKLLFIIDSLEGMECDLFKWESE----LCDNCTEKQPVNVLLSSLLRRKMLPESSLLISATPESFEKMENRIEYTHVKIIKGLKERNIKMSFHRLFQDRNRAHEAFSLVRENEQLFTVCQVPVLCWMVATCLKEEIEKGRDPVSICRCTTSLYTTHIFNLFIPQNAH--SPSKKSQDQLQGLCSLAAEGMWTDTFVFGEEALRRNGIMDSDIPILLDIGMLINIRES----EKSYIFLHPSVQEVCAAIFYLLKSH---------VDHPSQEVKSIEKLMFA-FLKKVKVQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNEELQEQIDGMKLFYCLFEMDDDTFLVEAMNCMEQINFV-AKDYSDVIVAAHCLKHCFTLKKLSFSTQNVLS------GAQEHS---------YMERLLTAWNHICSVFIISKDIQELRMKDTNLSESAFSVLYNNLKYHNYTLNVLVANNVFFVCEKYLFFELIQNC----------------------------------------------------------NLQHLNLSLTILSHSDVKLLCDVLSQAECNIEELVVAACSISSDDCKVFASVLIS-NKTLKHLNLASNTL-DKGIASLCKSLCHPDCILEHLVLANCSLNEKCWDYLSEVLRRN-KTLSHLDISSNDLKDEGLKVLCRALTLPDSVLKSLSLRHCLITISGCQDLAEVLRNN-QNLVSLQVSNNKLEDTGVKLLCDAIKHPNCHLEDLGLEACELTGACCEDLASTFTQCKT--LWAMNLLKNALDYNGLVVLCEALKQQTCATYVLGLQI-TDFDTETQAFLVAEQEKNPCLRILSSL---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96MN2-1", "uniprot_id": "NALP4_HUMAN", "id": "Q96MN2-1", "name": "NACHT, LRR and PYD domains-containing protein 4", "aln": "------------------------------------------------------MAASFFSDFGLMWYLEELKKEEFRKFKEHLKQ-------MTLQLELKQIPWTEVKKASREELANLLIKHYEEQQAWNITLRIFQKMDRKD--------------------------------------------------------------------LCMKVMRERTGYTKTYQAHAKQKFSRLWSSKSVTEIHLYFEEEVKQEECD-------------------------------HLDRLFAP-KEAGKQP-------RTVIIQGPQGIGKTTLLMKLMMAWSDNKIFRDRFLYTFYFCCRELR-ELPPTSLADLISREWPDPAAPITEIVSQPERLLFVIDSFEELQGGLNEPDSD----LCGDLMEKRPVQVLLSSLLRKKMLPEASLLIAIKPVCPKELRDQVTISEIYQPRGFNESDRLVYFCCFFKDPKRAMEAFNLVRESEQLFSICQIPLLCWILCTSLKQEMQKGKDLALTCQSTTSVYSSFVFNLFTPEGAE--GPTPQTQHQLKALCSLAAEGMWTDTFEFCEDDLRRNGVVDADIPALLGTKILLKYGER----ESSYVFLHVCIQEFCAALFYLLKSH---------LDHPHPAVRCVQELLVANFEKARRAHWIFLGCFLTGLLNKKEQEKLDAFFGFQLSQEIKQQIHQCLKSLGERGNPQGQVDSLAIFYCLFEMQDPAFVKQAVNLLQEANFH-IIDNVDLVVSAYCLKYCSSLRKLCFSVQNVFK------KEDEHSS--------TSDYSLICWHHICSVLTTSGHLRELQVQDSTLSESTFVTWCNQLRHPSCRLQKLGINNVSFSGQSVLLFEVLFYQP---------------------------------------------------------DLKYLSFTLTKLSRDDIRSLCDALNYPAGNVKELALVNCHLSPIDCEVLAGLLTN-NKKLTYLNVSCNQL-DTGVPLLCEALCSPDTVLVYLMLAFCHLSEQCCEYISEMLLRN-KSVRYLDLSANVLKDEGLKTLCEALKHPDCCLDSLCLVKCFITAAGCEDLASALISN-QNLKILQIGCNEIGDVGVQLLCRALTHTDCRLEILGLEECGLTSTCCKDLASVLTCSKT--LQQLNLTLNTLDHTGVVVLCEALRHPECALQVLGLRK-TDFDEETQALLTAEEERNPNLTITDDCDTITRVEI-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7RTR0-1", "uniprot_id": "NLRP9_HUMAN", "id": "Q7RTR0-1", "name": "NACHT, LRR and PYD domains-containing protein 9", "aln": "------------------------------------------------------MAESFFSDFGLLWYLKELRKEEFWKFKELLKQ-------PLEKFELKPIPWAELKKASKEDVAKLLDKHYPGKQAWEVTLNLFLQINRKD--------------------------------------------------------------------LWTKAQEEMRNKLNPYRKHMKETFQLIWEKETCLHVPEHFYKETMKNEYK-------------------------------ELNDAYT----AAARR-------HTVVLEGPDGIGKTTLLRKVMLDWAEGNLWKDRFTFVFFLNVCEMN-GIAETSLLELLSRDWPESSEKIEDIFSQPERILFIMDGFEQLKFNL-QLKAD----LSDDWRQRQPMPIILSSLLQKKMLPESSLLIALGKLAMQKHYFMLRHPKLIKLLGFSESEKKSYFSYFFGEKSKALKVFNFVRDNGPLFILCHNPFTCWLVCTCVKQRLERGEDLEINSQNTTYLYASFLTTVFKAGSQS--FPPKVNRARLKSLCALAAEGIWTYTFVFSHGDLRRNGLSESEGVMWVGMRLLQRRGD-------CFAFMHLCIQEFCAAMFYLLKRP---------KDDPNPAIGSITQLVRA-SVVQPQTLLTQVGIFMFGISTEEIVSMLETSFGFPLSKDLKQEITQCLESLSQCEADREAIAFQELFIGLFETQEKEFVTKVMNFFEEVFIY-IGNIEHLVIASFCLKHCQHLTTLRMCVENIFP------DDSGCIS--------DYNEKLVYWRELCSMFITNKNFQILDMENTSLDDPSLAILCKALAQPVCKLRKLIFTSVYFGHDSELFKAVLHNP----------------------------------------------------------HLKLLSLYGTSLSQSDIRHLCETLKHPMCKIEELILGKCDISSEVCEDIASVLAC-NSKLKHLSLVENPLRDEGMTLLCEALKHSHCALERLMLMYCCLTSVSCDSISEVLLCS-KSLSLLDLGSNALEDNGVASLCAALKHPGCSIRELWLMGCFLTSDSCKDIAAVLICN-GKLKTLKLGHNEIGDTGVRQLCAALQHPHCKLECLGLQTCPITRACCDDIAAALIACKT--LRSLNLDWIALDADAVVVLCEALSHPDCALQMLGLHK-SGFDEETQKILMSVEEKIPHLTISHGPWIDEEYKIRGVLL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86W25-1", "uniprot_id": "NAL13_HUMAN", "id": "Q86W25-1", "name": "NACHT, LRR and PYD domains-containing protein 13", "aln": "------------------------------------------------MNFSVITCPNGGTNQGLLPYLMALDQYQLEEFKLCLEPQQLMDFWSAPQGHFPRIPWANLRAADPLNLSFLLDEHFPKGQAWKVVLGIFQTMNLTSLCEKVRAEMKENVQTQELQDPTQEDLEMLEAAAGNMQTQGCQDPNQEELDELEEETGNVQAQGCQDPNQEEPEMLEEADHRRKYRENMKAELLETWDNISWPKDHVYIRN-TSKDEHE-------------------------------ELQRLLDP-NRTRAQA-------QTIVLVGRAGVGKTTLAMQAMLHWANGVLFQQRFSYVFYLSCHKIR-YMKETTFAELISLDWPDFDAPIEEFMSQPEKLLFIIDGFEEIIISESRSESLDDGSPCTDWYQELPVTKILHSLLKKELVPLATLLITIKTWFVRDLKASLVNPCFVQITGFTGDDLRVYFMRHFDDSSEVEKILQQLRKNETLFHSCSAPMVCWTVCSCLKQPKVRYYDLQSITQTTTSLYAYFFSNLFSTAEVD--LADDSWPGQWRALCSLAIEGLWSMNFTFNKEDTEIEGLEVPFIDSLYEFNILQKINDC----GGCTTFTHLSFQEFFAAMSFVLEEP--------REFPPHSTKPQEMKMLLQHVLLDKEAYWTPVVLFFFGLLNKNIARELEDTLHCKISPRVMEELLKWGEELGKAESASLQFHILRLFHCLHESQEEDFTKKMLGRIFEVDLN-ILEDEELQASSFCLKHCKRLNKLRLSVSSHILER---DLEILETS--------KFDSRMHAWNSICSTLVTNENLHELDLSNSKLHASSVKGLCLALKNPRCKVQKLTCKSVTPEWVLQDLIIALQGNS---------------------------------------------------------KLTHLNFSSNKLG-MTVPLILKALRHSACNLKYLCLEKCNLSAASCQDLALFLTS-IQHVTRLCLGFNRLQDDGIKLLCAALTHPKCALERLELWFCQLAAPACKHLSDALLQN-RSLTHLNLSKNSLRDEGVKFLCEALGRPDGNLQSLNLSGCSFTREGCGELANALSHN-HNVKILDLGENDLQDDGVKLLCEALK-PHRALHTLGLAKCNLTTACCQHLFSVLSSSKS--LVNLNLLGNELDTDGVKMLCKALKKSTCRLQKLG----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JW23-1", "uniprot_id": "A0A0G2JW23_RAT", "id": "A0A0G2JW23-1", "name": "NACHT, LRR and PYD domains-containing protein 12", "aln": "----------------------------------------------------MLPATAKDALHRLSTYLEELEAGELKKFKLYLG--------IAEELGQDKIPRGRMEMAGPLEMAQLMVAHMGTKEAWLLALSTFERIHRKDLWERGQGED--------------------------------LVRVTPSNGLC---SLESQST----CLSDVSPDAPRKDPQITYKDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPIWAQQKLLETGWEHSRTRGHQASPIQMETLFEPDEERPEPP-------RTVVLQGAAGMGKSMLTHKVMLDWADGRLFQDQFDYVFYISCRELNRSHTQCSVHDLLSSCWPEHGAPLEDLIRAPDRLLFIIDGFHELHPSFHDVQGP----WCHCWEEKRPTELLLGSLIRRLLLPQLSLLITTRPCALEKLHGLLEHPRHVEILGFSEAEREEYFYRYFHNTGQASQVFSFMRDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTSRTTTAVYMFYLLSLMQPKPGT--PTFKVPAN-QRGLVSLAAEGLWNQKILFEEEDLGKHGLDGAEVSTFLNVNIFQKGIKC----EKFYSFIHLSFQEFFTAMYCALHGRE------------------AVRRALAEYGFSERNFLAHTVRFLFGLLNEEMRCYLERNLGWTISPQVKEEALAWIQNKARSEGSTLQHGSLELLSCLYEIQEEDFIQQALSHFQVVVVRNLSTKMEHVVCSFCARYCRGTEVLHLYGSAYSTGAEDGPPEPPGAQTQSTHSQERNILPDIYSAYLSATICTNSNLIELALYRNALGSQGVRLLCQGLRHANCKLQNLRLKRCHISGSACQDLAAAIIAN--------------------------------------------------------RNLIRLDLSGNSIGVLGLELLCEGLQHPMCRLQMIQLRKCLLEAAAGRALASVLSN-NSHLVELDLTGNPLEDLGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMN-QSLMELDLGLNDLGDSGALLLCEGLRHPDCKLQTLRLGICRLGSDACAGVASVLQVN-TCLRELDLSFNDLGDRGLWLLGEGLRHQTCRLQKLWLDSCGLTSKACEDLSSVLGISQT--LNELYLTNNALGDTGVRLLCKRLRHPGCKLRVLWLFG-MDLNKVTHRRMAALRVTKPYLDIGC-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q5R7-1", "uniprot_id": "NAL12_MOUSE", "id": "E9Q5R7-1", "name": "NACHT, LRR and PYD domains-containing protein 12", "aln": "----------------------------------------------------MLPSTARDGLYRLSTYLEELEAGELKKFKLFLG--------IAEDLSQDKIPWGRMEKAGPLEMAQLMVAHMGTREAWLLALSTFQRIHRKDLWERGQGED--------------------------------LVRVTPNNGLC---LFESQSA----CPLDVSPNAPRKDLQTTYKDYVRRKFQLMEDRNARLGECVNLSNRYTRLLLVKEHSNPIWTQQKFVDVEWERSRTRRHQTSPIQMETLFEPDEERPEPP-------HTVVLQGAAGMGKSMLAHKVMLDWADGRLFQGRFDYVFYISCRELNRSHTQCSVQDLISSCWPERGISLEDLMQAPDRLLFIIDGFDKLHPSFHDAQGP----WCLCWEEKQPTEVLLGSLIRRLLLPQVSLLITTRPCALEKLHGLLEHPRHVEILGFSEEARKEYFYRYFHNTGQASRVLSFLMDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTPRTTTAVYMFYLLSLMQPKPGT--PTFKVPAN-QRGLVSLAAEGLWNQKILFDEQDLGKHGLDGADVSTFLNVNIFQKGIKC----EKFYSFIHLSFQEFFAAMYCALNGRE------------------AVRRALAEYGFSERNFLALTVHFLFGLLNEEMRCYLERNLGWSISPQVKEEVLAWIQNKAGSEGSTLQHGSLELLSCLYEVQEEDFIQQALSHFQVVVVRSISTKMEHMVCSFCARYCRSTEVLHLHGSAYSTGMEDDPPEPSGVQTQSTYLQERNMLPDVYSAYLSAAVCTNSNLIELALYRNALGSQGVRLLCQGLRHASCKLQNLRLKRCQISGSACQDLAAAVIAN--------------------------------------------------------RNLIRLDLSDNSIGVPGLELLCEGLQHPRCRLQMIQLRKCLLEAAAGRSLASVLSN-NSYLVELDLTGNPLEDSGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMN-QSLLELDLGLNDLGDSGVLLLCEGLSHPDCKLQTLRLGICRLGSVACVGIASVLQVN-TCLQELDLSFNDLGDRGLQLLGEGLRHQTCRLQKLWLDNCGLTSKACEDLSSILGISQT--LHELYLTNNALGDTGVCLLCKRLRHPGCKLRVLWLFG-MDLNKKTHRRMAALRVTKPYLDIGC-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P59046-1", "uniprot_id": "NAL12_HUMAN", "id": "P59046-1", "name": "NACHT, LRR and PYD domains-containing protein 12", "aln": "----------------------------------------------------MLRTAGRDGLCRLSTYLEELEAVELKKFKLYLG--------TATELGEGKIPWGSMEKAGPLEMAQLLITHFGPEEAWRLALSTFERINRKDLWERGQRED--------------------------------LVRDTPPGGPS---SLGNQST----CLLEVSLVTPRKDPQETYRDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPMQVQQQLLDTGRGHARTVGHQASPIKIETLFEPDEERPEPP-------RTVVMQGAAGIGKSMLAHKVMLDWADGKLFQGRFDYLFYINCREMNQSATECSMQDLIFSCWPEPSAPLQELIRVPERLLFIIDGFDELKPSFHDPQGP----WCLCWEEKRPTELLLNSLIRKKLLPELSLLITTRPTALEKLHRLLEHPRHVEILGFSEAERKEYFYKYFHNAEQAGQVFNYVRDNEPLFTMCFVPLVCWVVCTCLQQQLEGGGLLRQTSRTTTAVYMLYLLSLMQPKPGA--PRLQPPPN-QRGLCSLAADGLWNQKILFEEQDLRKHGLDGEDVSAFLNMNIFQKDINC----ERYYSFIHLSFQEFFAAMYYILDEGEG-----------GAGPDQDVTRLLTEYAFSERSFLALTSRFLFGLLNEETRSHLEKSLCWKVSPHIKMDLLQWIQSKAQSDGSTLQQGSLEFFSCLYEIQEEEFIQQALSHFQVIVVSNIASKMEHMVSSFCLKRCRSAQVLHLYGATYSADGEDRARCSAGAHTLLVQLPERTVLLDAYSEHLAAALCTNPNLIELSLYRNALGSRGVKLLCQGLRHPNCKLQNLRLKRCRISSSACEDLSAALIAN--------------------------------------------------------KNLTRMDLSGNGVGFPGMMLLCEGLRHPQCRLQMIQLRKCQLESGACQEMASVLGT-NPHLVELDLTGNALEDLGLRLLCQGLRHPVCRLRTLWLKICRLTAAACDELASTLSVN-QSLRELDLSLNELGDLGVLLLCEGLRHPTCKLQTLRLGICRLGSAACEGLSVVLQAN-HNLRELDLSFNDLGDWGLWLLAEGLQHPACRLQKLWLDSCGLTAKACENLYFTLGINQT--LTDLYLTNNALGDTGVRLLCKRLSHPGCKLRVLWLFG-MDLNKMTHSRLAALRVTKPYLDIGC-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A523-1", "uniprot_id": "NLRP3_RAT", "id": "D4A523-1", "name": "NACHT, LRR and PYD domains-containing protein 3", "aln": "----------------------------------------------------MKMMSVR---CKLAQYLEDLEDVDLKKFKMHLED-------YPPEKGCVPIPRGQMEKADHLDLATLMIDFNGEEKAWGMAVWIFAAINRRDLWEKAKKDQPEWN----------------------------DACTSNLSMVCQEDSLEEEWIGLLGYLSRISICKKKKDYCKIYRRHVRSRFYSIKDRNARLGESVDLNRRYTQLQLVKEHPSKQEREHELLTIGR--TKMWDRPMSSLKLELLFEPEDEHLEPV-------HTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVS-LRAPKSLADLIISCWPDPNPPVCKILCKPSRILFLMDGFDELQGAFDEHIEE----VCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEILFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGI--EEHLFSAY-LPGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDC----ERFYSFSHMTFQEFFAAMYYLLEEEEEGVTVRKGPEGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQRQPSQLELFYCLYEMQEEDFVQSAMGHFPKIEIN-LSTRMDHVVSSFCIKNCHRVKTLSLGFLHNSPKEEEEEK------------------------------------------RGSQPLDQVQCVFP-DPHVACSSR---LVNCCLTSSFCRGLFSSLSTN--------------------------------------------------------QSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLTHQCCFNISSVLSS-SQKLVELDLSDNALGDFGVRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSN-HSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSLCCSALTSVLKTN-QNLTHLYLRSNALGDMGLKLLCEGLLHPDCKLQMLELDNCSLTSHSCWDLSTILTHNQS--LRKLNLSNNDLGDLCVVTLCEVLKQQGCLLQSLQLGE-MYLNCETKRTLEALQEEKPELTVVFEISW-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4B8-1", "uniprot_id": "NLRP3_MOUSE", "id": "Q8R4B8-1", "name": "NACHT, LRR and PYD domains-containing protein 3", "aln": "------------------------------------------------------MTSVR---CKLAQYLEDLEDVDLKKFKMHLED-------YPPEKGCIPVPRGQMEKADHLDLATLMIDFNGEEKAWAMAVWIFAAINRRDLWEKAKKDQPEWN----------------------------DTCTSHSSMVCQEDSLEEEWMGLLGYLSRISICKKKKDYCKMYRRHVRSRFYSIKDRNARLGESVDLNSRYTQLQLVKEHPSKQEREHELLTIGR--TKMRDSPMSSLKLELLFEPEDGHSEPV-------HTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVS-LRTPRSLADLIVSCWPDPNPPVCKILRKPSRILFLMDGFDELQGAFDEHIGE----VCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEVLFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGI--EEHLFSDY-LQGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDC----ERFYSFSHMTFQEFFAAMYYLLEEEAEGETVRKGPGGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQWQPSQLELFYCLYEMQEEDFVQSAMDHFPKIEIN-LSTRMDHVVSSFCIKNCHRVKTLSLGFFHNSPKEEEEER------------------------------------------RGGRPLDQVQCVFP-DTHVACSSR---LVNCCLTSSFCRGLFSSLSTN--------------------------------------------------------RSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLSHQCCFDISSVLSS-SQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSN-HSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSICCSALTSVLKTN-QNFTHLYLRSNALGDTGLRLLCEGLLHPDCKLQMLELDNCSLTSHSCWNLSTILTHNHS--LRKLNLGNNDLGDLCVVTLCEVLKQQGCLLQSLQLGE-MYLNRETKRALEALQEEKPELTIVFEISW-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96P20-1", "uniprot_id": "NLRP3_HUMAN", "id": "Q96P20-1", "name": "NACHT, LRR and PYD domains-containing protein 3", "aln": "----------------------------------------------------MKMASTR---CKLARYLEDLEDVDLKKFKMHLED-------YPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSD--------------------------NARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQQEREQELLAIGK--TKTCESPVSPIKMELLFDPDDEHSEPV-------HTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVS-LVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGP----LCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGS--QEHGLCAH-LWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDC----EKFYSFIHMTFQEFFAAMYYLLEEEKEGRTN--VPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEIN-LSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEE------------------------------------------KEGRHLDMVQCVLPSSSHAACSHG---LVNSHLTSSFCRGLFSVLSTS--------------------------------------------------------QSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSS-NQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTS-HSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTN-QNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQS--LRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSE-MYFNYETKSALETLQEEKPELTVVFEPSW-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NX02-1", "uniprot_id": "NALP2_HUMAN", "id": "Q9NX02-1", "name": "NACHT, LRR and PYD domains-containing protein 2", "aln": "------------------------------------------------------MVSSAQMGFNLQALLEQLSQDELSKFKYLITT-------FSLAHELQKIPHKEVDKADGKQLVEILTTHCDSYWVEMASLQVFEKMHRMDLSERAKDEVR-------------------------------------------EAALKSFNKRKPLSLGITRKERPPLDVDEMLERFKTEAQAFTETKGNVICLGKEVFKGKKPDKDNRCRYILKTKFREMWKSWPGDSKEVQVMAERYKMLIPFSNPRVLPGPFS------YTVVLYGPAGLGKTTLAQKLMLDWAEDNLIH-KFKYAFYLSCRELS-RLGPCSFAELVFRDWPELQDDIPHILAQARKILFVIDGFDELGAAPGALIED----ICGDWEKKKPVPVLLGSLLNRVMLPKAALLVTTRPRALRDLRILAEEPIYIRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPTCLTRTGLFLRFLCSRFPQG-------AQLRGA-LRTLSLLAAQGLWAQTSVLHREDLERLGVQESDLRLFLDGDILRQDRVS----KGCYSFIHLSFQQFLTALFYTLEKEEEEDRD------GHTWDIGDVQKLLSGVERLRNPDLIQAGYYSFGLANEKRAKELEATFGCRMSPDIKQELLRCDISCKG--GHSTVTDLQELLGCLYESQEEELVKEVMAQFKEISLH--LNAVDVVPSSFCVKHCRNLQKMSLQVIKENLPENVTASESDAEVERS----QDDQHMLPFWTDLCSIFGSNKDLMGLAINDSFLSASLVRILCEQIASDTCHLQRVVFKNISP-ADAHRNLCLALRGH--------------------------------------------------------KTVTYLTLQGNDQDD-MFPALCEVLRHPECNLRYLGLVSCSATTQQWADLSLALEV-NQSLTCVNLSDNELLDEGAKLLYTTLRHPKCFLQRLSLENCHLTEANCKDLAAVLVVS-RELTHLCLAKNPIGNTGVKFLCEGLRYPECKLQTLVLWNCDITSDGCCDLTKLLQEK-SSLLCLDLGLNHIGVKGMKFLCEALRKPLCNLRCLWLWGCSIPPFSCEDLCSALSCNQS--LVTLDLGQNPLGSSGVKMLFETLTCSSGTLRTLRLKI-DDFNDELNKLLEEIEEKNPQLIIDTEKHHPWAERPSSHDFMI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P59047-1", "uniprot_id": "NALP5_HUMAN", "id": "P59047-1", "name": "NACHT, LRR and PYD domains-containing protein 5", "aln": "MKVAGGLELGAAALLSASPRALVTLSTGPTCSILPKNPLFPQNLSSQPCIKMEGDKSLTFSSYGLQWCLYELDKEEFQTFKELLKK-------KSSESTTCSIPQFEIENANVECLALLLHEYYGASLAWATSISIFENMNLRTLSEKARDDMKRHS------------------------------PEDPEATMTDQGPSKEKVPGISQAVQQDSATAAETKEQEISQAMEQEGATAAETEEQEISQAMEQEGATAAETEEQGHGGDTWDYKSHVMTKFAEEEDVRRSFENTAADWPEMQTLAGAFDSDRWGFRPRTVVLHGKSGIGKSALARRIVLCWAQGGLYQGMFSYVFFLPVREMQ-RKKESSVTEFISREWPDSQAPVTEIMSRPERLLFIIDGFDDLGSVLNNDTKL-----CKDWAEKQPPFTLIRSLLRKVLLPESFLIVTVRDVGTEKLKSEVVSPRYLLVRGISGEQRIHLLLERGIGEHQKTQGLRAIMNNRELLDQCQVPAVGSLICVALQLQDVVGESVAPFNQTLTGLHAAFVFHQLTPRGVVRRCLNLEERVVLKRFCRMAVEGVWNRKSVFDGDDLMVQGLGESELRALFHMNILLPDSHC----EEYYTFFHLSLQDFCAALYYVLEGLEIEP-------ALCPLYVEKTKRSMELKQAGFHIHSLWMKRFLFGLVSEDVRRPLEVLLGCPVPLGVKQKLLHWVSLLGQQPNATTPGDTLDAFHCLFETQDKEFVRLALNSFQEVWLP-INQNLDLIASSFCLQHCPYLRKIRVDVKGIFPRDESAEACPVVPLWMR-----DKTLIEEQWEDFCSMLGTHPHLRQLDLGSSILTERAMKTLCAKLRHPTCKIQTLMFRNAQITPGVQHLWRIVMANRNLRSLNLGGTHLKEEDVRMACEALKHPKCLLESLRLDCCGLTHACYLKISQILTTSPSLKSLSLAGNKVTDQGVMPLSDALRVSQCALQKLILEDCGITATGCQSLASALVS-NRSLTHLCLSNNSLGNEGVNLLCRSMRLPHCSLQRLMLNQCHLDTAGCGFLALALMGN-SWLTHLSLSMNPVEDNGVKLLCEVMREPSCHLQDLELVKCHLTAACCESLSCVISRS-RHLKSLDLTDNALGDGGVAALCEGLKQKNSVLARLGLKACGLTSDCCEALSLALSCNRH--LTSLNLVQNNFSPKGMMKLCSAFACPTSNLQIIGLWK-WQYPVQIRKLLEEVQLLKPRVVIDGSWHSFDEDDRYWWKN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YU37-1", "uniprot_id": "A0A8M6YU37_DANRE", "id": "A0A8M6YU37-1", "name": "", "aln": "--------------------------------------------------------MEDNQTFSDAPVCSNESNPEFEPSCVSMKSDQ-----SMDPPMKFKEGHTSADLSDRLNPPGSSCVSMKSDWSMDRPIQFKEEHSSADLSNKSNPGEPSCVS-------------------------------------SKSDQSMGPPINVMEEHSAADLRLDPHLKQNGLRSNLLRKFQCLYEGTAMQGDPTLLNEIYTELYITESDSGEINNKHELRQIETR-SRRSATEDTPIQCRDIFTPLPGQDKAIR-------TVLTKGVAGIGKTVSVQKFIVDWAEEKENQD-IQLIFPLPFREIN-LMKDRTLSLSDLLQVFFPETKEMEISSEQFKVLFIFDGLDECRVSLDFKCDVK----LHDVSESASVDVLLTNLIMGNLLPSALIWITSRPAAADLIPSEFVHR-VTEIRGFNDPQKEEYFRKRIRDQFLADIIIINLKSSRSLHIMCHIPVFCWISATVLEKIFSQAQS-GEIPKTLTQMYTHFLIMQTNIRHEKDYEEEVRDEDMILKLGKLAFEQLVKGNLIFYEEDLRECGLDVTEASVYSGLCTQIFREEFGFYQGKVFCFVHLSIQEHLAALYAHHSLTN----------------------------KNRNVFKQTKPSLLSKVLNQKKHDSLSVLHQRAVKEASQSKNGHLDLFLRFLLGLSLESSGTLLRELLTQTGSCSYNKEETVQYIKQKIRENRSPERSINLFHCLNELGEDSLMQEIQDYLSSG---------------------------------------------EIKETKLSSSQWSALVYVLLTSEKK------------------------------------------------------------------------------------MDFFDLSKFIGPQLRADVVLQKLLPVVKESRSVRLGDCKVTDKVCAALASALRLNSSHLTQLDLIGNKLGDSGVKLLSDGLKDPHCKLKNLMMRDCGVTDEGCAALASALRSNSTHLTELNLNENNLGDAGVKRLSDGLKGPHCKLEILRLWRCGVRDEGCAALASALSSNSTHLKELELSDNKLGDSGVKLLSDALKDPHCKLEKLRLNGCGVREQGCVSLALALRFNPSSHLTELDLTSNELGKSGVKLLSDLRDDPRYKLRHLACDMFGRIIVSSGGGRLDELLPTTSTET-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7N0-1", "uniprot_id": "A1Z7N0_DROME", "id": "A1Z7N0-1", "name": "Leucine-rich repeat-containing protein 34", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCDVLLPCEYNPKECPSPAAEKSRLFTILLLYCWQREYDKRPYRQFQFKRLTFEERIGRRYHCIRDLRIIVNYLLRRPQLSVQISSLVVSNWDAGLLKDFVRSLLPVWYIELRLMRFPREFF------------------VMLRLNAAKMNVSQLSLEGTPLTDEDVRILREFLLVSKTLRR------------------------------------------------------------LNVSSCSLTQFNFALIADGVYK------------------------------------------------SPGVRRLSANRLLGMSLSLDTEKISSVLSSLLMQNT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LWALSLEHCELTAQDMIPIAEHLARTNSKFRRLRIACNKIGPDGAFFLLRGMSMG-GNLELLDLSYCSIGTHGGEWVAKYLASC-RRLQVLHLNYNDMGPTAVNLILLAMKK-QCKLEKLTLYGNHFDSRTAMIVRRLLDAEVVLHSELDISYT---------YDEALQDYRVVPWR-----------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : : : : . . : . . : : . . . . : : * : * . : : * : * : : * * : * . :: : : * : * : . : : * : . . : : . * : . .: ", "identical_positions": 11, "similar_positions": 48, "identity": "0.87%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-290", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29144-1", "uniprot_id": "TPP2_HUMAN", "id": "P29144-1", "name": "Tripeptidyl-peptidase 2", "aln": "MATAATEEPFPFHGLLPKKETGAASFLCRYPEYDGRGVLIAVLDTGVDPGAPGMQVTTDGKPKIVDIIDTTGSGDVNTATEVEPKDGEIVGLSGRVLKIPASWTNPSGKYHIGIKNGYDFYPKALKERIQKERKEKIWDPVHRVALAEACRKQEEFDVANNGSSQANKLIKEELQSQVELLNSFEKKYSDPGPVYDCLVWHDGEVWRACIDSNEDGDLSKSTVLRNYKEAQEYGSFGTAEMLNYSVNIYDDGNLLSIVTSGGAHGTHVASIAAGHFPEEPERNGVAPGAQILSIKIGDTRLSTMETGTGLIRAMIEVINHKCDLVNYSYGEATHWPNSGRICEVINEAVWKHNIIYVSSAGNNGPCLSTVGCPGGTTSSVIGVGAYVSPDMMVAEYSLREKLPANQYTWSSRGPSADGALGVSISAPGGAIASVPNWTLRGTQLMNGTSMSSPNACGGIALILSGLKANNIDYTVHSVRRALENTAVKADNIEVFAQGHGIIQVDKAYDYLVQNTSFAN-KLGFTVTVGNNRGIYLRDPVQVAAPSDHGVGIEPVFPENTENSEKISLQLHLALTSNSSWVQCPSHLELMNQCRHINIRVDPRGLREGLHYTEVCGYDIASPNAGPLFRVPITAVIAAKVNESSHYDLAFTDVHFKPGQIRRHFIEVPEGATWAEVTVCSCSSEVSAKFVLHAVQLVKQRAYRSHEFYKFCSLPEKGTLTEAFPVLGGKAIEFCIARWWASLSDVNIDYTISFHGIVCTAPQLNIHASEGINRFDVQSSLKYEDLAPCITLKNWVQTLRPVSAKTKPLGSRDVLPNNRQLYEMVLTYNFHQPKSGEVTPSCPLLCELLYESEFDSQLWIIFDQNKRQMGSGDAYPHQYSLKLEKGDYTIRLQIRHEQISDLERLKDLPFIVSHRLSNTLSLDIHENHSFALLGKKKSSNLTLPPKYNQPFFVTSLPDDKIPKGAGPGCYLAGSLTLSKTELGKKA--------------DVIPVHYYLIPPPTKTKNGSKDKEKDSEKEKDLKEEFTEALRDLKIQWMTKLDSSDIYNELKETYPNYLPLYVARLHQLDAEKERMKRLNEIVDAANAVISHIDQTALAVYIAMKTDPRPDAATIKNDMDKQKSTLVDALCRKGCALADHLLHTQAQDGAISTDAEGKEEEGESPLDSLAETFWETTKWTDLFDNKVLTFAYKHALVNKMYGRGLKFATKLVEEKPTKENWKNCIQLMKLLGWTHCASFTENWLPIMYPPDYCVF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64514-1", "uniprot_id": "TPP2_MOUSE", "id": "Q64514-1", "name": "Tripeptidyl-peptidase 2", "aln": "MATAATEEPFPFHGLLPKKETGASSFLCRYPEYDGRGVLIAVLDTGVDPGAPGMQVTTDGKPKIIDIIDTTGSGDVNTATEVEPKDGEIIGLSGRVLKIPANWTNPLGKYHIGIKNGYDFYPKALKERIQKERKEKIWDPIHRVALAEACRKQEEFDIANNGSSQANKLIKEELQSQVELLNSFEKKYSDPGPVYDCLVWHDGETWRACVDSNENGDLSKCAVLRNYKEAQEYSSFGTAEMLNYSVNIYDDGNLLSIVTSGGAHGTHVASIAAGHFPEEPERNGVAPGAQILSIKIGDTRLSTMETGTGLIRAMIEVINHKCDLVNYSYGEATHWPNSGRICEVINEAVWKHNTIYVSSAGNNGPCLSTVGCPGGTTSSVIGVGAYVSPDMMVAEYSLREKLPANQYTWSSRGPSADGALGVSISAPGGAIASVPNWTLRGTQLMNGTSMSSPNACGGIALVLSGLKANNVDYTVHSVRRALENTAIKADNIEVFAQGHGIIQVDKAYDYLIQNTSFAN-RLGFTVTVGNNRGIYLRDPVQVAAPSDHGVGIEPVFPENTENSEKISFQLHLALTSNSSWVQCPSHLELMNQCRHINIRVDPRGLREGLHYTEVCGYDIASPNAGPLFRVPITAVIAAKVNESSHYDLAFTDVHFKPGQIRRHFVEVPEGATWAEVTVCSCSSEVSAKFVLHAVQLVKQRAYRSHEFYKFCSLPEKGTLIEAFPVLGGKAIEFCIARWWASLSDVNIDYTISFHGIVCTAPQLNIHASEGINRFDVQSSLKYEDLAPCITLKSWVQTLRPVNAKTRPLGSRDVLPNNRQLYEMVLTYSFHQPKSGEVTPSCPLLCELLYESEFDSQLWIIFDQNKRQMGSGDAYPHQYSLKLEKGDYTIRLQIRHEQISDLDRLKDLPFIVSHRLSNTLSLDIHENHSLALLGKKKSSSLTLPPKYNQPFFVTSLPDDKIPKGAGPGCYLAGSLTLSKTELGKKAG-QSAAKRQGKFKKDVIPVHYYLIPPPTKIKNGSKDKEKDSEKEKDLKEEFTEALRDLKIQWMTKLDSTDIYNELKETYPAYLPLYVARLHQLDAEKERMKRLNEIVDAANAVISHIDQTALAVYIAMKTDPRPDAATIKNDMDKQKSTLIDALCRKGCALADHLLHTQPHDGAAAGDAEAKEEEGESTMESLSETYWETTKWTDLFDTKVLIFAYKHALVNKMYGRGLKFATKLVEEKPTKENWKNCIQLMKLLGWTHCASFTENWLPIMYPPDYCVF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "R4GDQ0-1", "uniprot_id": "R4GDQ0_DANRE", "id": "R4GDQ0-1", "name": "Tripeptidyl-peptidase 2", "aln": "MSAHSAEEPFPFHGLLPKKETGAASFLTKYPEYDGRGVLIAILDTGVDPGAPGMQITTDGKPKIVDIIDTTGSGDVNMSTVVEVKEGSVSGLTGRTLKIPAAWVNPSGKYHIGVKNGYDFFPKALKERIQKERKEKLWDPTHRAALAEASRRTEEFDQTHTNPSQMEKLQKEELQCHVELLGMLEKKYSDPGPVYDCISWHDGVTWRAVVDTSECGDLSSCTVLSSYRERQEFCTLGFAEMLNFSVNIYDEGNTLCIVTSGGAHGTHVASIAAGHFPDEPERNGVAPGAQILALKIGDTRLSTMETGTGLIRAMIEVINYKCDLVNYSYGEATHWPNSGRICEVITEAVQKYNVMFVSSAGNNGPCLTTVGCPGGTTSSVIGVGAYVTPDMMVAEYSLREKLPPNQYTWSSRGPCTDGALGVSISAPGGAIASVPNWTLRGTQLMNGTSMSSPNACGGIALVLSGLKQNGLRPTVPAVRRALENTAQKVEEIEVFAQGHGIIQVERAFDYLMQHNSLASSSLGFSVSAGSQRGIYLRDATHVTAPSDHGVGIEPIFPENTENAARISLQLHLALVCNASWVQCPSHLELMNQCRHVNVRIDPQGLREGLHYTEVCGYDTTALSAGPLFRVPITVIIPTKVSDSRSQELSFTDVHFRPGQIRRHFITVPQGASWAEISLTSHTGDVSSKFVLHAVHLVKQRAYRANEFYKFSSLLEKGSLTEAFPVLPGRTLELCIARWWASLGDVTIDYVISFHGLVTSPSPIHIHASEGISSFEVCSPLRYEDVSPTITLKNWVQPLRPVSSKIKPLGMRDVLPNNRQLYELVLTYNFHQPKSGEVTPSCPLLCELLYESEFDSQLWLLFDQNKRLMGSGDAYPHQYSLKLEKGDYTVRLQVRHEQQSELERLKDLPFVVSHRLSNTLSLDVYETHRAALLAKKKANSITLSPGASQPFYITSLPDDKIPKGSGPGGFISGSLVLPKSEFGKKAQGQASAKRQGKFKKDIVPIFYHLVPAPNKSKNG-KEKEKDPEKEKDVKEEFSEALRDLKIQWMSKLDNSSLYEELKEAFPTHLPLHVQRLHQLDSEKERLKRLPEIVSAAESVMSHIDQTALAVYLTMKTDPRPDAASIKSDMEKQKASLLDALCRKGCALADQLMQTPLQDGASAGQVSSSEEESVGVAKALTDTFWELQKWAELTDSKVLSFSYKHALANKMYARALKYAIKIVEDKPSRENSKNCLQLMRSLGWTHCVSFTESWLPILFPADFTPF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: ::*****************:*** :************:*************:********:************ :* ** *:*.: **:**.***** *.** ******:******:***************:*** **.*****.*: **** ::...** :** *****.:****. :*************: **** .*** :*:.* ****..:** .*:* **: ::* *****:******:** *.*********************:**************::*************************:*************************.*** *:* ::***********:*******************:***************.**********.:*********************************************:***** *.: ** :********* *.::*************::*:***:*:.*:*. ***:*:.*.:*******..:*:***********:*******: :**:******..*:*****************:*:*:**:*************** :: .**********.:*.:**.:* :*:******:********: **:**:***::: * :.:**:*******:********::*****.** ***:* ****** *:::*:*********.**.***.*****:* :.. ::*******. *:* *.*:***::* ****.***.****.:* :*** ************:****.******************************::****** *********************:***:**** *:*:*******:************::*.* ***.***:..:**.* .***::***********:*** :::***.*.*:*:**** *::*:.*:*:*.*.* *** *:****.*****:****:***********:***.:.:*:****::* :***:* ******:****:*** ***.**::*:***********::**********:**.**:***::*:************:*::* :*** : :....***. . .:*::*:** **::* *.*** *:*****.****.*.**:* *:**:**::** ***:***: ******.****.****::*.*: *", "identical_positions": 922, "similar_positions": 249, "identity": "72.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-293", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97608-1", "uniprot_id": "OPLA_RAT", "id": "P97608-1", "name": "5-oxoprolinase", "aln": "MGSPEGRFHFAIDRGGTFTDVFAQCPGGHV---RVLKLLSEDPANYADAPTEGIRRILEQEEGVLLPRGRPLDTSRIASIRMGTTVATNALLERQGERVALLVTRGFRDLLHIGTQARPDLFDLAVPMPEVLYEEVLEVDERVVLYRG-------EPGAGSP---VKGRTGDLLEIQQPVDLEALRGKLEGLLSRGIHSLAVVLMHSYTWAQHEQQVGTLARELGFTHVSLSSEVMPMVRIVPRGHTACADAYLTPTIQRYVQGFRRGFQGQLKNVQVLFMRSDGGLAPMDAFSGSRAVLSGPAGGVVGYSATTYHLEGGQPVIGFDMGGTSTDVSRY-AGEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRLFFRSGLFVVGPESAGAHPGPACYRKGGPVTVTDANLVLGRLLPASFPCIFGPGEDQPLSPEASRKALEAVAMEVNSFLTNGPCP-------ASQLSLEEVAMGFVRVANEAMCRPIRALTQARGHDPSAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLSY-TPETFAQLDQRLSRLEEQCVDALQVQGFPRSQISTESFLHLRYQGTDCALMVSAHQHPATACS----PRAGDFGAAFVERYMREFGFIIPERPVVVDDVRVRGTGRSGLQLEDTPKIQTGP----------PHVEKVTQCYFEGGYQETPVYLLGELGYGHQLQGPCLIIDNNSTILVEPGCQAEVTDTGDIRISVGAEGPSMAD-----TRLDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQETVQFQIQHLGADLHPGDVLLSNHPSAGGSHLPDLTVITPVFWPGQTRPVFYVASRGHHADIGGITPGSMPPHSTTLQQEGAVFLSFKLVQGGVFQEEAVTEALR-APGKISGCSGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQYGLDVVQAYMGHIQANAELAVRDMLRAFGTSRQARGLPLEVSAEDHMDDGSPICLRVQINLSQGSAVFDFTGSGSEVFGNLNAPRAITLSALIYCLRCLVGRDIPLNQGCLAPVRVIIPKGSILDPSPEAAVVGGNVLTSQRVVDVILGAFGACSASQGCMNNVTLGN------------ARMGYYETVAGGAGAGP------GWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELRP-GSGGRGRFRGGDGVVRELVFREEALLSVLTERRAFQPYGLHGGEPGARGLNLLIRK-DGRTVNLGGKTSVTVYPGDVFCLHTPGGGGYGDPEDP--APPPGSPPLFPAFPERGSVFEYRRAQEAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K010-1", "uniprot_id": "OPLA_MOUSE", "id": "Q8K010-1", "name": "5-oxoprolinase", "aln": "MGSPEERFHFAIDRGGTFTDVFAQCPGGHV---RVLKLLSEDPANYADAPTEGIRRILEQERGVLLPRGRPLDTSHIASIRMGTTVATNALLERQGERVALLVTRGFRDLLHIGTQARPDLFDLAVPMPEVLYEEVVEVDERVLLYRG-------EPGAGSP---VKGCTGDLLEIQQPVDLAALRGKLEGLLTRGIHSLAVVLMHSYTWAQHEQQVGTLARELGFTHVSLSSEVMPMVRIVPRGHTACADAYLTPTIQRYVQGFRRGFQGQLKNVQVLFMRSDGGLAPMDAFSGSRAVLSGPAGGVVGYSTTTYQLEGGQPVIGFDMGGTSTDVSRY-AGEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRLFFRSGLFVVGPESAGAHPGPACYRKGGPVTVTDANLVLGRLLPASFPCIFGPGEDQPLSPEASRKALEAVAMEVNSFLASGPCP-------ASQLSLEEVAMGFVRVANEAMCRPIRALTQARGHDPSAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLSY-TPETFAQLDQRLSRLEEQCVDALQAQGFSRSQISTESFLHLRYQGTDCALMVSANQHPATTCS----PRAGDFGAAFVERYMREFGFIIPERSVVVDDVRVRGTGRSGLQLEETSKIQSGP----------PHVEKVTQCYFEGGYQETPVYLLGELGYGHQLQGPCLIIDNNSTILVEPGCQAEVIETGDIRISVGAEAPSMID-----TKLDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQETVQFQIQHLGADLHPGDVLLSNHPSAGGSHLPDLTVITPVFWPGQSRPVFYVASRGHHADIGGITPGSMPPHSTTLQQEGAVFLSFKLVQGGVFQEEAVTEALQ-APGKISGCSGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQYGLDVVQAYMGHIQANAELAVRDMLRAFGTSRQARGLPLEVSAKDHMDDGSPICLHVQINLNQGSAVFDFSGSGSEVFGNLNAPRAITLSALIYCLRCLVGRDIPLNQGCLAPVQVIIPKGSILDPSPEAAVVGGNVLTSQRVVDVILGAFGACAASQGCMNNVTLGN------------ARMGYYETVAGGAGAGP------GWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELRP-GSGGRGRFRGGDGVVRELVFREEALLSVLTERRAFQPYGLHGGEPGTRGLNLLIRK-DGRTVNLGGKTSVTVYPGDAFCLHTPGGGGYGDPEDP--APPPGSPPLYPAFPERGSVYEYRRAQEAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14841-1", "uniprot_id": "OPLA_HUMAN", "id": "O14841-1", "name": "5-oxoprolinase", "aln": "MGSPEGRFHFAIDRGGTFTDVFAQCPGGHV---RVLKLLSEDPANYADAPTEGIRRILEQEAGMLLPRDQPLDSSHIASIRMGTTVATNALLERKGERVALLVTRGFRDLLHIGTQARGDLFDLAVPMPEVLYEEVLEVDERVVLHRG-------EAGTGTP---VKGRTGDLLEVQQPVDLGALRGKLEGLLSRGIRSLAVVLMHSYTWAQHEQQVGVLARELGFTHVSLSSEAMPMVRIVPRGHTACADAYLTPAIQRYVQGFCRGFQGQLKDVQVLFMRSDGGLAPMDTFSGSSAVLSGPAGGVVGYSATTYQQEGGQPVIGFDMGGTSTDVSRY-AGEFEHVFEASTAGVTLQAPQLDINTVAAGGGSRLFFRSGLFVVGPESAGAHPGPACYRKGGPVTVTDANLVLGRLLPASFPCIFGPGENQPLSPEASRKALEAVATEVNSFLTNGPCP-------ASPLSLEEVAMGFVRVANEAMCRPIRALTQARGHDPSAHVLACFGGAGGQHACAIARALGMDTVHIHRHSGLLSALGLALADVVHEAQEPCSLLY-APETFVQLDQRLSRLEEQCVDALQAQGFPRSQISTESFLHLRYQGTDCALMVSAHQHPATARS----PRAGDFGAAFVERYMREFGFVIPERPVVVDDVRVRGTGRSGLRLEDAPKAQTGP----------PRVDKMTQCYFEGGYQETPVYLLAELGYGHKLHGPCLIIDSNSTILVEPGCQAEVTKTGDICISVGAEVPGTVG-----PQLDPIQLSIFSHRFMSIAEQMGRILQRTAISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQETVQFQIQHLGADLHPGDVLLSNHPSAGGSHLPDLTVITPVFWPGQTRPVFYVASRGHHADIGGITPGSMPPHSTMLQQEGAVFLSFKLVQGGVFQEEAVTEALR-APGKVPNCSGTRNLHDNLSDLRAQVAANQKGIQLVGELIGQYGLDVVQAYMGHIQANAELAVRDMLRAFGTSRQARGLPLEVSSEDHMDDGSPIRLRVQISLSQGSAVFDFSGTGPEVFGNLNAPRAVTLSALIYCLRCLVGRDIPLNQGCLAPVRVVIPRGSILDPSPEAAVVGGNVLTSQRVVDVILGAFGACAASQGCMNNVTLGN------------AHMGYYETVAGGAGAGP------SWHGRSGVHSHMTNTRITDPEILESRYPVILRRFELRR-GSGGRGRFRGGDGVTRELLFREEALLSVLTERRAFRPYGLHGGEPGARGLNLLIRK-NGRTVNLGGKTSVTVYPGDVFCLHTPGGGGYGDPEDP--APPPGSPPQALAFPEHGSVYEYRRAQEAV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F6Z6-1", "uniprot_id": "E7F6Z6_DANRE", "id": "E7F6Z6-1", "name": "", "aln": "MAETKGKFDFAIDRGGTFTDVFARLPDGRE---KVLKLLSHDPQNYKDAPTEGIRRVLEEETGKSFPRDQPVDTSQIGWIRMGTTVATNALLERQGERTALLVTSGFKDLLHIGTQARPNLFDLEVCMPDVLYEEVIEVEERVILRQDSC-----QLPRNEPKRIVTGSTGESLEVWRELDLQRVEQDLRRVQSKGIRSLAVLLLHSYTWAAHEKAVGSLAKRLGFAQVSLSSEVMPMVRAVPRGYTVCADAYLTPKIHLYLTKFTAGFKGGLKGVDVLFMQSDGGLTPMEQFCGSRAVLSGPAGGVVGYAVTCYKSTEKKPVIGFDMGGTSTDVSRY-AGQYEHVFEATIAGITLQAPQLDINTVAAGGGSRLFFRSGMFVVGPESAGAHPGPACYRKGGPLTVTDANLALGRLLPSFFPKIFGPGENEPLSTEETMKHFSKLTQEINHFLSTNQTSNSASGAQLSKMSIEDIAMGFINVANEAMCRPIRALTQAKGHDTSEHVLACFGGAGGQHACAIARALGMKMVFIHKYSGVLSAYGLALADVVEEVQEPCSLQY-EAGSFSELDRRIEQLSQRCDEILRKRGFSRSQINIEVFLHLRYEGTDCALMITATDHPSNASS----CRTGDFRTAFTKRYLKEFGFTITDRPIMVDDIRVRGSGKSGIRSEVQAKAGQKS----------PNPIKMTQCYFEDRYLDTSVYLWEDLSCDHSIQGPAIIIDKNSTILVEPTCVAHLTEDGDVCIAVGMGTQCVLG-----TELNTIQLSIFSHRFMSIAEQMGRVLQRTAISTNIKERLDFSCAVFGPDGGLVSNAPHIPVHLGAMQETVQFQIKAAGGSLKEGDVILSNHPCAGGSHLPDLTVITPVFRDGVSAPVFFVASRGHHADIGGITPGSMPPHSTSLQQEGAVFTSFKLVTGGIFQEKAVTEALM-APAQYPGCSGTRNLRDNLSDLRAQVAANQRGCQLVGELITSYGLDVVQAYMGHIQSNAELAVRDMLKDFAHRQREKTGSLEVEAEDQMDDGTLIRLKVQINEEQGSAVFDFTGTGTEVWGNCNAPRAITLSALIYCLRCMVGQDIPLNQGCLAPVKVIIPPGSILQPSQNAAVVGGNVLTSQRVVDVIFKAFQVCAASQGCMNNVSFGC------------EKSGYYETVAGGAGAGP------SWNGRGGIHTHMTNTRITDPEILESRYPVILEQFSLRP-DSGGAGLYRGGDGVIRKLRFRSPVVLSVLTERRSTKPYGLHGGKNGAPGLNLLHKT-DGRVLNLGAKTTISLDPGDMFSLFTPGGGGYGRMDEL--DGDHHLPSKRRCLHE---------SQNKV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W247-1", "uniprot_id": "Q9W247_DROME", "id": "Q9W247-1", "name": "5-oxoprolinase", "aln": "MSGT--KYCFAIDRGGTFTDVLCICPNGKV---RTMKLLSEDPERYSDAPREGIRRILKEETGEDLAASGLVDTSKIGWVRMGTTVATNALLERKGDPVVLVVNSGFRDLLYIGNQARPKIFDLNIRKPANLYKSVVEVDCRIVPKQAD------RCELNHSWKELEGVAGTKYLEVRPVDEVAVRQALSDARDQGVSSVSVVLAHSYACPEHELRVGAIARELGFSHVTLSHQAMPMCRVVARGYTACAEAYLTPHVDRYLASFKSGFDKQLEGVDVLFMQSDGGLTNMENFRGARAILSGPAGGVVGYALTGAR-ETELPLIGFDMGGTSTDVSRY-AGTYEHVIESTTAGVTIQAPQLDINTVAAGGGSRLFFRSGIFVVGPESAGSHPGPACYKKGGPLTVTDANLILGRILPQYFPKIFGPQENEPLDHEIARSKFVELQAEINNYLKSSGDN--------RVLSVEDVALGFIRVANETMCRPIRALTQSRGLDTANHVLSCFGGAGGQHACSIARNLGIAKVVVHKYAGILSAYGMALADVVQEFQEPNGLEF-SDANAQQLKERLDALSKQCQDKLSEQGFKR--IELEPFLHLRYEGTDGALMVAPSTGKQSSDSNPLLAAYGDFHATFLERYRTEFGFVLQNRRIIVDDIRIRGLGKNETPPESKVQAAAEAK---------PPAEANTRLYFDQGAFDSPIYLTKNLLAGHRITGPAVLIDQLSTIVVEPECGIQVTQFGDLIMDVKTGGKHGIN-----ADLDPVHLSIFSHRFMSIAEQMGRVLQRTSISTNIKERLDFSCALFGPDGGLVSNAPHIPVHLGAMQETVQYQLRVRGETLKNGDVILANHPSAGGSHLPDLTVITPVFYETHPRPVFFVASRGHHADIGGITPGSMPPHSTSLAQEGAAFKSFLIVENGLFQEQQIIEQLT-TPTAAKGAVGTRNLSDNLSDLKAQIAANHKGIQLVAELIGSYGLDVVQAYMSHIQKNAELAVRDMLRQIGRDTLERTGSTVLEAKEFMDDGSPIALKVTIDAEQGSALCDFTGSGVEVWGNCNAPRAITLSALIYCLRCMVGHDVPLNQGCLAPIQVIIPKNSILDPSEGAAVVGGNVQTSQRIVDTVLKAFGVCAASQGCMNNITIGD------------ESWGYYETVAGGAGAGP------GWHGAGGVHTHMTNTRITDPEILELRYPMILKRFCLRTDGSGGRGQFHGGEGVERDLLFRKPVTLSVLTERRTLQPYGLAGGESGKSGRNLVVKR-DGRVIALAGKTCIDVEAGDTFAMKTPGGGGYGPIEDFSKSGESLNQETSKRYVERGTVFNYLQCQESA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P28273-1", "uniprot_id": "OPLA_YEAST", "id": "P28273-1", "name": "5-oxoprolinase", "aln": "--MQKGNIRIAIDKGGTFTDCVGNIGTGKQEHDTVIKLLSVDPKNYPDAPLEGIRRLLEVLEHKTIPRGIPLDISNVRSLRMGTTLATNCALERNGERCAFITTKGFKDSLLIGDQTRPDIFNLNIKKVVPLYDTVVEIDERVTLEDFSEDPYFTKSSPNEQEGILEGNSGEMVRVIKKPDESSVRSILKVLYASGIKSIAIAFLHSYTFPDHERIVGNIAREIGFSHVSLSSEVSPMIKFLPRAHSSVADAYLTPVIKKYLNSISAGLS-HAEDTHIQFMQSDGGLVDGGKFSGLKSILSGPAGGVIGYSSTCYDKNNNIPLIGFDMGGTSTDVSRYGDGRLEHVFETVTAGIIIQSPQLDIHTVAAGGSSILSWKNGLFRVGPDSAAADPGPAAYRKGGPLTITDANLFLGRLVPEFFPKIFGPNEDESLDLETTTLKFRELTDVINKDLN-------------SNLTMEEVAYGFIKVANECMARPVRAITEAKGHVVSQHRLVSFGGAGGQHAIAVADSLGIDTVLIHRYSSILSAYGIFLADVIEENQEPCSFILGEPETILKVKKRFLELSKNSIKNLLSQSFSREDIVLERYLNLRYEGTETSLMILQKYDDQ-----------WNFREWFSEAHKKEFGFSFDDKRIIIDDIRIRAIGKSGVRKEKTVDEQLIEISHFKKADVSKDASFTQKAYFDNKWVDTAVFKIDDLPAGTIIEGPAILADGTQTNIILPNSQATILN-SHIFIKINQKAAKTLSKSGYELDIDPILLSIFSHRFMDIALQMGTQLRKTSVSTNVKERLDFSCALFDSKGNLVANAPHVPVHLGSMSTCISAQAKLWEGKLKPGDVLITNHPDIGGTHLPDITVITPSFSSTG-ELIFYVASRAHHADIGGILPGSVPPNSKELYEEGTAIYSELVVKEGIFQEELIYKLFVEDPGKYPGCSGSRRFSDNISDLKAQVAANTKGIQLIGSLTKEYDLATILKYMAAIQTNASESIKKMLAKM----VEHFGTTKFSGEDRLDDGSLIKLQVIIRPEKEEYIFNFDGTSPQVYGNLNAPEAITNSAILYCLRCLVGEDIPLNQGCLKPLTIKIPAGSLLSPRSGAAVVGGNVLTSQRVTDVILKTFNVMADSQGDCNNFTFGTGGNSGNKTDKQIKGFGYYETICGGSGAGADSWRGSGWNGSDAVHTNMTNTRMTDTEVFERRYPVLLKEFSIRR-GSGGKGKYTGGNGVVRDVQFRKAVTASILSERRVIGPHGIKGGQDGSRGENLWVRHSTGALINVGGKNTIYAQPGDRFIIKTPGGGGFGQYKD--------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :***:****** . *: .:**** ** .* *** *****:*: :. . :* *.: :*****:***. ***:*: .::.. **:* * ** *:* .:*:* : **. *:*:: *: . . : * :* : * :. * *: *::: : ***: . ** ** :*:.:**::*:** :. ** : :.*.:: *:***** :. *: : *:. :...: **:*****. * * ::********:**: * *:*************** * ***:*: **: :*:*****:******.* * ::.*:* ***:**.:.****.*:****:*:***** ***::* ** **** *::.*. * : : : :* * :::*::* **:.**** *.**:**:*:::* : * * .********* ::* **: * :*:::.:*** *: ****:.* *** .: . ::..*: *.:.. . * :.* * * * :*:***:**: :**: :* * : : **** : :: :::**:*:*. *:. * . : **: ::.:: :* . : **.:: * .* :: * . : . ..: : : . ::.: *********.** *** *::*::***:*********:*...*.**:****:*****:*. :. * : *: ***:::*** **:****:***** * :*:****.******** ***:**:*. * :**:.: * :* *:***: : : : * .. *:*.: **:***:**:*** :* **:..* .*.* .: **. ** **. :::.** : : . ...:: :***: * *:* * .: . : :* *:. :*:** ***.*:* **::*****:**.*:******* *: : ** .*:*.* ******** ****:.*.:: :* . : *** **.::* *****:.**:***. .*:* ..:*::*****:**.*::* ***::*..* :* .*** * : **:** *.: **. . *:*:*** *:*: **: * * ** : * : :..*. : .** * : ******:* .: ", "identical_positions": 498, "similar_positions": 355, "identity": "36.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-30", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M918-1", "uniprot_id": "F1M918_RAT", "id": "F1M918-1", "name": "", "aln": "------------------------------------------------------------------------------------MKTEDEEMEDQLSK------------------------------------------------------------------------------------------EEIVSEDKEFD----YRTIIKENFFIIWDKTSLLGESATLNCVTTHKDQK-------------------------------LLEHIFDVNIQTSKSPQTVVLYGAAGIGKTTLLKKAVLEWADGNLYQQ-FTHVFYLSGREIS-QEKEKNFAQLISKHWPSSEGPIEQILCKPSSLLFILDSFDELDFSFEEPEFA----LCRDWTQKHPVSFLISSLLRKVMLPESYLLVTTRTTAWKRLVPLLQKPHRVKLPGLSRSSRIDYIHHLLKDKTWAMNAVCSIRMNAKLFNMCHVCHVCQMICTFLKEQVEKGGNVEMT-CQTSTALFTYYICSLFPRIAGSSVTLPNETLLRSLCQAAVEGIWTMKHVLYQQNLRKHELTREDLSLFLEANVLQQDTEC----ENCYTFTHLQVQEYFAALFYLLRENPEEKDH------PLEPFENVHLLLESNHFHDP--HLEQMKCFLFGLLNKDRVQQLEETFNLTISRAVREELLVCLEALEKDDSPLSQLRIQDLLHCIYETQDEEFITQALTYFQKIMVK-VDEESKLLIYSYCLKHCHSLQTVRLTARADLRNMLDP---TAEICLED----------AAVRIIHYWQDLFSVLHTNESLLEMDLYESRLDESLMKILNEEFSHPKCNLQKVMFRAVCFLNSCYDFS-FLAFNNTVTHLDLKDTDLGDNGVKTLCEALKYQGCKLRVLRLESCDLNVTHCQNLSKALQSNRSLVFLNLSTN-SLSNDGVKSLCEVLENPNCPLERLALASCGLTKVGCEVLSSALT-KTKRLTHLCLAHNVLEDEGIELLSYTLRHPRCTLQSLVLRCCYFTPIGSEHLSTALQNN-KSLIHLDLGFNKLADSGVKLLCQTLQQPNCNLQELELMGCVLTSEACGDLASVLVNN-SNLWNLDLGNNILDDAGLNILCEALRNPNCQIRRLGLENCGLTPGCCQDLLDLLSNNQSVIQMNLMKNSLDYEAIRNLCKVLRSPTCKMEFLALDKKDLFKKKIKKFLVDVRINNPHLVIRPQCP--NTESGCWWQYF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6B966-1", "uniprot_id": "NAL14_MOUSE", "id": "Q6B966-1", "name": "NACHT, LRR and PYD domains-containing protein 14", "aln": "------------------------------------------------------------------------------------MKTEDDEMEYEASK------------------------------------------------------------------------------------------EETVSEDKDFDDGIDYRTVIKENIFTMWYKTSLHGEFATLNCVITPKDQN-------------------------------LLQHIFDEDIQTSEAPQTVVLQGAAGIGKTTLLKKAVLEWADGNLYQQ-FTHVFYLNGKEIS-QVKEKSFAQLISKHWPSSEGPIEQVLSKPSSLLFIIDSFDELDFSFEEPQFA----LCKDWTQISPVSFLISSLLRKVMLPESYLLVATRSTAWKRLVPLLQKPQRVKLSGLSKNARMDYIHHLLKDKAWATSAIYSLRMNWRLFHMCHVCHMCQMICAVLKGQVEKGGRVEET-CKTSTALFTYYICSLFPRIPVGCVTLPNETLLRSLCKAAVEGIWTMKHVLYQQNLRKHELTREDILLFLDAKVLQQDTEY----ENCYMFTHLHVQEFFAALFYLLRENLEEQDY------PSEPFENLYLLLESNHIHDP--HLEQMKCFLFGLLNKDRVRQLEETFNLTISMEVREELLACLEGLEKDDSSLSQLRFQDLLHCIYETQDQEFITQALMYFQKIIVR-VDEEPQLRIYSFCLKHCHTLKTMRLTARADLKNMLD----TAEMCLEG----------AAVQVIHYWQDLFSVLHTNESLIEMDLYESRLDESLMKILNEELSHPKCKLQKLIFRAVDFLNGCQDFT-FLASNKKVTHLDLKETDLGVNGLKTLCEALKCKGCKLRVLRLASCDLNVARCQKLSNALQTNRSLVFLNLSLN-NLSNDGVKSLCEVLENPNSSLERLALASCGLTKAGCKVLSSALT-KSKRLTHLCLSDNVLEDEGIKLLSHTLKHPQCTLQSLVLRSCSFTPIGSEHLSTALLHN-RSLVHLDLGQNKLADNGVKLLCHSLQQPHCNLQELELMSCVLTSKACGDLASVLVNN-SNLWSLDLGHNILDDAGLNILCDALRNPNCHVQRLGLENCGLTPGCCQDLLGILSNNKSVIQMNLMKNALDHESIKNLCKVLRSPTCKMEFLALDKKEILKKKIKKFLVDVRINNPHLVIGPECP--NTESGCWWNYF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86W24-1", "uniprot_id": "NAL14_HUMAN", "id": "Q86W24-1", "name": "NACHT, LRR and PYD domains-containing protein 14", "aln": "--------------------------MADSSSSSFFPDFGLLLYLEELNKEELNTFKLFLKET-------MEPEHGLTP-WNEVKKARREDLANLMKKYYPGEKAWSVSLKIFGKMNLKDLCERAKEEINW--------------------------------------------SAQTIGPDDAKAGETQEDQEAVLGDGTEYRNRIKEKFCITWDKKSLAGKPEDFHHGIAEKDRK-------------------------------LLEHLFDVDVKTGAQPQIVVLQGAAGVGKTTLVRKAMLDWAEGSLYQQRFKYVFYLNGREIN-QLKERSFAQLISKDWPSTEGPIEEIMYQPSSLLFIIDSFDELNFAFEEPEFA----LCEDWTQEHPVSFLMSSLLRKVMLPEASLLVTTRLTTSKRLKQLLKNHHYVELLGMSEDAREEYIYQFFEDKRWAMKVFSSLKSNEMLFSMCQVPLVCWAACTCLKQQMEKGGDVTLT-CQTTTALFTCYISSLFTPVDGGSPSLPNQAQLRRLCQVAAKGIWTMTYVFYRENLRRLGLTQSDVSSFMDSNIIQKDAEY----ENCYVFTHLHVQEFFAAMFYMLKGSWEAGNP------SCQPFEDLKSLLQSTSYKDP--HLTQMKCFLFGLLNEDRVKQLERTFNCKMSLKIKSKLLQCMEVLGNSDYSPSQLGFLELFHCLYETQDKAFISQAMRCFPKVAIN-ICEKIHLLVSSFCLKHCRCLRTIRLSVTVVFEKKILK---TSLPTNTW----------DGDRITHCWQDLCSVLHTNEHLRELDLYHSNLDKSAMNILHHELRHPNCKLQKLLLKFITFPDGCQDISTSLIHNKNLMHLDLKGSDIGDNGVKSLCEALKHPECKLQTLRLESCNLTVFCCLNISNALIRSQSLIFLNLSTN-NLLDDGVQLLCEALRHPKCYLERLSLESCGLTEAGCEYLSLALI-SNKRLTHLCLADNVLGDGGVKLMSDALQHAQCTLKSLVLRRCHFTSLSSEYLSTSLLHN-KSLTHLDLGSNWLQDNGVKLLCDVFRHPSCNLQDLELMGCVLTNACCLDLASVILNN-PNLRSLDLGNNDLQDDGVKILCDALRYPNCNIQRLGLEYCGLTSLCCQDLSSALICNKRLIKMNLTQNTLGYEGIVKLYKVLKSPKCKLQVLGLCK-EAFDEEAQKLLEAVGVSNPHLIIKPDCNYHNEEDVSWWWCF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZP31-1", "uniprot_id": "D3ZP31_RAT", "id": "D3ZP31-1", "name": "", "aln": "-------------------------------MASFFSDFGLMWYLEELNKKEFVKFKEFLKQE-------ILQLRLKQISWTKVKKASREDLANLLLKHYEEKQAWDMTFKIFQKMNRKD--------------------------------------------------------------------LIERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKAQDLFKQKFTQDDCD-------------------------------RFENLLVS-KATGKKPHMVFLQGVAGIGKSLMLTKLMLAWSEGIVFQNKFSYIFYFCCQDVK-QLKRASLAELISREWPNASAPTAEILSQPEKLLFIIDSLEVMECNMSERESE----LCDNCTEKQPVSLLLSSLLRRKMLPESSFLISATPETFEKMEDRIECTNVKIITGFNENNIKMYFRSLFQDKNRTLEAFSLVRENEQLFNVCQVPVLCWMVATCIKKEIEKGRDPVFI-CRRTTSLYTTHIFNLFTPQNAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFSEEALRRNGILDSDIPTLLDRRILERSKES----ESCYIFLHPSLQEVCAAVFYLLK---SHLDH------PSQDVKSVEALLFTFLKKAK-VQWIFLGCFLFGLLHESEQEKLEMFFGHQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEAFLMQAMNCMEQINFV-AKDYSDVIVAAYCLKHCSTLKKLSFSTQNILS---------EEQEHS-----------YTEKLLICWHHMCSVLISSKDIHVLQVKDTNLNETAFWVLYNHLKYPSCTLKVLVVNNVTFLC---------------------------------------------------------DNHLFFELIQNQ-RLQHLNLSLT-FLSHSDVKLLCDVLNQAECNIEKLMIAACNLSPDDCKVFASVLI-SSKMLKHLNLSSNNL-DKGISSLCKALCHPDCILKHLVLANCSLSEQCWDYLSEVVRRN-KTLSHLDISSNDLKDEGLKVLCGALTLPDSGLISLSVRHCLITTSGCQDLAEVLRHN-QNLRSLQVSNNKIEDAGVKLLCDAIKQPNCHLENIGLEACELTGACCKDLASAFVHCKTLWGINLLENALDHSGLVVLFEALKQQKCTLHVLGLRI-TDFDKETQEFLIAEEEKNPYLSILSNV---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZUH1-1", "uniprot_id": "D3ZUH1_RAT", "id": "D3ZUH1-1", "name": "", "aln": "-------------------------------MASFFSDFGLMWYLEELNKKEFMKFKEFLKQE-------ILQLGLKQVSWTEVKKASREDLASLLLKHYEEKQAWDMTFNFFQKINRKD--------------------------------------------------------------------LIKRAKREIDGYPKLYRAHLKTKLTHDSSRIFNINIQDFLKEKFTKDDHD-------------------------------RFETLLQS-KGTESKPQVVVLSGVAGIGKTLMLKRLMLAWIEGLVFPYKFSYIFYFCCQEVK-QLKTASLAELISREWPDPSAPIEEILSEPEKLLFIIDSLEGIECDLFKCDSE----LCDNCMEKQPVNILLSSLLRKKMLLEASLLISTTPETFEKMEDRIEYTHVKIITGLNESDIKMCFHRLFQDRNRAQEAFSLVRENEQMLTICQVPVLCWMVATCLKTEIEKGRNLVST-CRRTTSLYTTYIFNLFIPQSAHSPSKKSQDQLQGLCSLAAEGIWTDTFVFTEEALRRNGILDSDIPTLLDIGMLGKMGKF----ENCYIFLHPSLQEACAAIFYLLK---SHGDH------PIEDVKSVEALLFTFLKKAK-VQWILGGRFIFGLLHESEQKKLEAFFGHQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEDFLMEAMNYMEQINFV-AKDYSDVIVAAYCLKHCYTLKKLSFSTQNILN---------EEHEHS-----------CMENLLTCWRHICSVLINSKDIQELQIKDTNLNEPAFSVLYNSLKYCNDTLKVLVENNVFFLC---------------------------------------------------------EKYLFFELIQNC-NLQHLNLNLT-FLSHSDVKLLCDVLNQAECNIEKLEVAACNLSPDDCKMFASILM-SSKTLKQLNLSSNIL-GKGISSLCKSLCHPDCILEHLVLAKCSLSDQCWDYLSDGIRQN-KTLNHLDISSNDLKDEGLKVLCRALALPNSVLKSLCLRHCLITTSGCQDLAEVLRNN-QNLTSLQISYNKIEDAGVKLLCDAIKQPNCHLEDLGLEACELTGACCEDLASTFTQCRTLWGINLLNNTLDYTGLVVLCEALRQQKCTPHVLGLRI-TDFDNETQAFLVAEQEKNPDLSILSGV---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96MN2-1", "uniprot_id": "NALP4_HUMAN", "id": "Q96MN2-1", "name": "NACHT, LRR and PYD domains-containing protein 4", "aln": "------------------------------MAASFFSDFGLMWYLEELKKEEFRKFKEHLKQM-------TLQLELKQIPWTEVKKASREELANLLIKHYEEQQAWNITLRIFQKMDRKD--------------------------------------------------------------------LCMKVMRERTGYTKTYQAHAKQKFSRLWSSKSVTEIHLYFEEEVKQEECD-------------------------------HLDRLFAP-KEAGKQPRTVIIQGPQGIGKTTLLMKLMMAWSDNKIFRDRFLYTFYFCCRELR-ELPPTSLADLISREWPDPAAPITEIVSQPERLLFVIDSFEELQGGLNEPDSD----LCGDLMEKRPVQVLLSSLLRKKMLPEASLLIAIKPVCPKELRDQVTISEIYQPRGFNESDRLVYFCCFFKDPKRAMEAFNLVRESEQLFSICQIPLLCWILCTSLKQEMQKGKDLALT-CQSTTSVYSSFVFNLFTPEGAEGPTPQTQHQLKALCSLAAEGMWTDTFEFCEDDLRRNGVVDADIPALLGTKILLKYGER----ESSYVFLHVCIQEFCAALFYLLK---SHLDH------PHPAVRCVQELLVANFEKARRAHWIFLGCFLTGLLNKKEQEKLDAFFGFQLSQEIKQQIHQCLKSLGERGNPQGQVDSLAIFYCLFEMQDPAFVKQAVNLLQEANFH-IIDNVDLVVSAYCLKYCSSLRKLCFSVQNVFK---------KEDEHSS----------TSDYSLICWHHICSVLTTSGHLRELQVQDSTLSESTFVTWCNQLRHPSCRLQKLGINNVSFSG---------------------------------------------------------QSVLLFEVLFYQPDLKYLSFTLT-KLSRDDIRSLCDALNYPAGNVKELALVNCHLSPIDCEVLAGLLT-NNKKLTYLNVSCNQL-DTGVPLLCEALCSPDTVLVYLMLAFCHLSEQCCEYISEMLLRN-KSVRYLDLSANVLKDEGLKTLCEALKHPDCCLDSLCLVKCFITAAGCEDLASALISN-QNLKILQIGCNEIGDVGVQLLCRALTHTDCRLEILGLEECGLTSTCCKDLASVLTCSKTLQQLNLTLNTLDHTGVVVLCEALRHPECALQVLGLRK-TDFDEETQALLTAEEERNPNLTITDDCDTITRVEI-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7RTR0-1", "uniprot_id": "NLRP9_HUMAN", "id": "Q7RTR0-1", "name": "NACHT, LRR and PYD domains-containing protein 9", "aln": "------------------------------MAESFFSDFGLLWYLKELRKEEFWKFKELLKQP-------LEKFELKPIPWAELKKASKEDVAKLLDKHYPGKQAWEVTLNLFLQINRKD--------------------------------------------------------------------LWTKAQEEMRNKLNPYRKHMKETFQLIWEKETCLHVPEHFYKETMKNEYK-------------------------------ELNDAYT----AAARRHTVVLEGPDGIGKTTLLRKVMLDWAEGNLWKDRFTFVFFLNVCEMN-GIAETSLLELLSRDWPESSEKIEDIFSQPERILFIMDGFEQLKFNL-QLKAD----LSDDWRQRQPMPIILSSLLQKKMLPESSLLIALGKLAMQKHYFMLRHPKLIKLLGFSESEKKSYFSYFFGEKSKALKVFNFVRDNGPLFILCHNPFTCWLVCTCVKQRLERGEDLEIN-SQNTTYLYASFLTTVFKAGSQSFPPKVNRARLKSLCALAAEGIWTYTFVFSHGDLRRNGLSESEGVMWVGMRLLQRRGD-------CFAFMHLCIQEFCAAMFYLLK---RPKDD------PNPAIGSITQLVRASVVQPQ-TLLTQVGIFMFGISTEEIVSMLETSFGFPLSKDLKQEITQCLESLSQCEADREAIAFQELFIGLFETQEKEFVTKVMNFFEEVFIY-IGNIEHLVIASFCLKHCQHLTTLRMCVENIFP---------DDSGCIS----------DYNEKLVYWRELCSMFITNKNFQILDMENTSLDDPSLAILCKALAQPVCKLRKLIFTSVYFGH---------------------------------------------------------DSELFKAVLHNP-HLKLLSLYGT-SLSQSDIRHLCETLKHPMCKIEELILGKCDISSEVCEDIASVLA-CNSKLKHLSLVENPLRDEGMTLLCEALKHSHCALERLMLMYCCLTSVSCDSISEVLLCS-KSLSLLDLGSNALEDNGVASLCAALKHPGCSIRELWLMGCFLTSDSCKDIAAVLICN-GKLKTLKLGHNEIGDTGVRQLCAALQHPHCKLECLGLQTCPITRACCDDIAAALIACKTLRSLNLDWIALDADAVVVLCEALSHPDCALQMLGLHK-SGFDEETQKILMSVEEKIPHLTISHGPWIDEEYKIRGVLL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86W25-1", "uniprot_id": "NAL13_HUMAN", "id": "Q86W25-1", "name": "NACHT, LRR and PYD domains-containing protein 13", "aln": "------------------------MNFSVITCPNGGTNQGLLPYLMALDQYQLEEFKLCLEPQQLMDFWSAPQGHFPRIPWANLRAADPLNLSFLLDEHFPKGQAWKVVLGIFQTMNLTSLCEKVRAEMKENVQTQELQDPTQEDLEMLEAAAGNMQTQGCQDPNQEELDELEEETGNVQAQGCQDPNQEEPEMLEEADHRRKYRENMKAELLETWDNISWPKDHVYIRNTS-KDEHE-------------------------------ELQRLLDP-NRTRAQAQTIVLVGRAGVGKTTLAMQAMLHWANGVLFQQRFSYVFYLSCHKIR-YMKETTFAELISLDWPDFDAPIEEFMSQPEKLLFIIDGFEEIIISESRSESLDDGSPCTDWYQELPVTKILHSLLKKELVPLATLLITIKTWFVRDLKASLVNPCFVQITGFTGDDLRVYFMRHFDDSSEVEKILQQLRKNETLFHSCSAPMVCWTVCSCLKQPKVRYYDLQSI-TQTTTSLYAYFFSNLFSTAEVDLADDSWPGQWRALCSLAIEGLWSMNFTFNKEDTEIEGLEVPFIDSLYEFNILQKINDC----GGCTTFTHLSFQEFFAAMSFVLEE--PREFP------PHSTKPQEMKMLLQHVLLDKEAYWTPVVLFFFGLLNKNIARELEDTLHCKISPRVMEELLKWGEELGKAESASLQFHILRLFHCLHESQEEDFTKKMLGRIFEVDLN-ILEDEELQASSFCLKHCKRLNKLRLSVSSHILER------DLEILETS----------KFDSRMHAWNSICSTLVTNENLHELDLSNSKLHASSVKGLCLALKNPRCKVQKLTCKSVTPEW---------------------------------------------------------VLQDLIIALQGNSKLTHLNFSSN-KLG-MTVPLILKALRHSACNLKYLCLEKCNLSAASCQDLALFLT-SIQHVTRLCLGFNRLQDDGIKLLCAALTHPKCALERLELWFCQLAAPACKHLSDALLQN-RSLTHLNLSKNSLRDEGVKFLCEALGRPDGNLQSLNLSGCSFTREGCGELANALSHN-HNVKILDLGENDLQDDGVKLLCEALK-PHRALHTLGLAKCNLTTACCQHLFSVLSSSKSLVNLNLLGNELDTDGVKMLCKALKKSTCRLQKLG----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86W28-1", "uniprot_id": "NALP8_HUMAN", "id": "Q86W28-1", "name": "NACHT, LRR and PYD domains-containing protein 8", "aln": "MSDVNPPSDTPIPFSSSSTHSSHIPPWTFSCYPGSPCENGVMLYMRNVSHEELQRFKQLLLTELS--------TGTMPITWDQVETASWAEVVHLLIERFPGRRAWDVTSNIFAIMNCDKMCVVVRREINAILP-------------------------------------------TLEPEDLNVGETQVNLEEGESGKIRRYKSNVMEKFFPIWDITTWPGNQRDFFYQGVHRHEE-------------------------------YLPCLLLPKRPQGRQPKTVAIQGAPGIGKTILAKKVMFEWARNKFYAHKRWCAFYFHCQEVN-QTTDQSFSELIEQKWPGSQDLVSKIMSKPDQLLLLLDGFEELTSTLIDRLED----LSEDWRQKLPGSVLLSSLLSKTMLPEATLLIMIRFTSWQTCKPLLKCPSLVTLPGFNTMEKIKYFQMYFGHTEEGDQVLSFAMENTILFSMCRVPVVCWMVCSGLKQQMERGNNLTQS-CPNATSVFVRYISSLFPTRAENFSRKIHQAQLEGLCHLAADSMWHRKWVLGKEDLEEAKLDQTGVTAFLGMSILRRIAGE----EDHYVFTLVTFQEFFAALFYVLCFPQRLKNF------HVLSHVNIQRLIASPRGSKS--YLSHMGLFLFGFLNEACASAVEQSFQCKVSFGNKRKLLKVIPLLHKCDPPSPGSGVPQLFYCLHEIREEAFVSQALNDYHKVVLR-IGNNKEVQVSAFCLKRCQYLHEVELTVTLNFMNVWKLSSSSHPGSEAP----------ESNGLHRWWQDLCSVFATNDKLEVLTMTNSVLGPPFLKALAAALRHPQCKLQKLLLRRVNSTMLN---------------------------------------------------------QDLIGVLTGNQHLRYLEIQHV-EVESKAVKLLCRVLRSPRCRLQCLRLEDCLATPRIWTDLGNNLQ-GNGHLKTLILRKNSLENCGAYYLS------VAQLERLSIENCNLTQLTCESLASCLRQS-KMLTHLSLAENALKDEGAKHIWNALPHLRCPLQRLVLRKCDLTFNCCQDMISALCKN-KTLKSLDLSFNSLKDDGVILLCEALKNPDCTLQILELENCLFTSICCQAMASMLRKNQHLRHLDLSKNAIGVYGILTLCEAFSSQKKREEVIFCIP-----AWTRITSFSPTPHPPDFTGKSDCLSQINP---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8WX94-1", "uniprot_id": "NALP7_HUMAN", "id": "Q8WX94-1", "name": "NACHT, LRR and PYD domains-containing protein 7", "aln": "-------------------------------MTSPQLEWTLQTLLEQLNEDELKSFKSLLWAFP-------LEDVLQKTPWSEVEEADGKKLAEILVNTSSENWIRNATVNILEEMNLTELCKMAKAEMMEDGQ---------------------------------------------------VQEIDNPELGDAEEDSELAKPGEKEGWRNSMEKQSLVWKNTFWQG---DIDN----------------FHDD------VTLRNQRFIPFLNPRTPRKLTPYTVVLHGPAGVGKTTLAKKCMLDWTDCNLSPT-LRYAFYLSCKELS-RMGPCSFAELISKDWPELQDDIPSILAQAQRILFVVDGLDELKVPPGALIQD----ICGDWEKKKPVPVLLGSLLKRKMLPRAALLVTTRPRALRDLQLLAQQPIYVRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPT-CLTRTGLFLRFLCSRFPQG------AQLRGALRTLSLLAAQGLWAQMSVFHREDLERLGVQESDLRLFLDGDILRQDRVS----KGCYSFIHLSFQQFLTALFYALEKEEGEDRD------GHAWDIGDVQKLLSGEERLKNPDLIQVGHFLFGLANEKRAKELEATFGCRMSPDIKQELLQCKAHLHAN-KPLSVTDLKEVLGCLYESQEEELAKVVVAPFKEISIH-LTNTSEVMHCSFSLKHCQDLQKLSLQVAKGVFLENYMDFELDIEFERCTYLTIPNWARQDLRSLRLWTDFCSLFSSNSNLKFLEVKQSFLSDSSVRILCDHVTRSTCHLQKVEIKNVTPDT---------------------------------------------------------AYRDFCLAFIGKKTLTHLTLAGHIEWERTMMLMLCDLLRNHKCNLQYLRLGGHCATPEQWAEFFYVLK-ANQSLKHLRLSANVLLDEGAMLLYKTMTRPKHFLQMLSLENCRLTEASCKDLAAVLVVS-KKLTHLCLAKNPIGDTGVKFLCEGLSYPDCKLQTLVLQQCSITKLGCRYLSEALQEA-CSLTNLDLSINQI-ARGLWILCQALENPNCN---------------------------------------------------------LKHLRLKT-YETNLEIKKLLEEVKEKNPKLTIDCNASG--ATAPPCCDFFC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NX02-1", "uniprot_id": "NALP2_HUMAN", "id": "Q9NX02-1", "name": "NACHT, LRR and PYD domains-containing protein 2", "aln": "------------------------------MVSSAQMGFNLQALLEQLSQDELSKFKYLITTFS-------LAHELQKIPHKEVDKADGKQLVEILTTHCDSYWVEMASLQVFEKMHRMDLSERAKDEVREAALK------------------------------------------SFNKRKPLSLGITRKERPPLDVDEMLERFKTEAQAFTETKGNVICLGKEVFKGKKPDKDNRCRYILKTKFREMWKSWPGDSKEVQVMAERYKMLIPFSNPRVLPGPFSYTVVLYGPAGLGKTTLAQKLMLDWAEDNLIHK-FKYAFYLSCRELS-RLGPCSFAELVFRDWPELQDDIPHILAQARKILFVIDGFDELGAAPGALIED----ICGDWEKKKPVPVLLGSLLNRVMLPKAALLVTTRPRALRDLRILAEEPIYIRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPT-CLTRTGLFLRFLCSRFPQG------AQLRGALRTLSLLAAQGLWAQTSVLHREDLERLGVQESDLRLFLDGDILRQDRVS----KGCYSFIHLSFQQFLTALFYTLEKEEEEDRD------GHTWDIGDVQKLLSGVERLRNPDLIQAGYYSFGLANEKRAKELEATFGCRMSPDIKQELLRCDISCKG--GHSTVTDLQELLGCLYESQEEELVKEVMAQFKEISLH-LN-AVDVVPSSFCVKHCRNLQKMSLQVIKENLPENVTASESDAEVERS---------QDDQHMLPFWTDLCSIFGSNKDLMGLAINDSFLSASLVRILCEQIASDTCHLQRVVFKNISPAD---------------------------------------------------------AHRNLCLALRGHKTVTYLTLQGNDQDD--MFPALCEVLRHPECNLRYLGLVSCSATTQQWADLSLALE-VNQSLTCVNLSDNELLDEGAKLLYTTLRHPKCFLQRLSLENCHLTEANCKDLAAVLVVS-RELTHLCLAKNPIGNTGVKFLCEGLRYPECKLQTLVLWNCDITSDGCCDLTKLLQEK-SSLLCLDLGLNHIGVKGMKFLCEALRKPLCNLRCLWLWGCSIPPFSCEDLCSALSCNQSLVTLDLGQNPLGSSGVKMLFETLTCSSGTLRTLRLKI-DDFNDELNKLLEEIEEKNPQLIIDTEKHHPWAERPSSHDFMI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2JW23-1", "uniprot_id": "A0A0G2JW23_RAT", "id": "A0A0G2JW23-1", "name": "NACHT, LRR and PYD domains-containing protein 12", "aln": "----------------------------MLPATAKDALHRLSTYLEELEAGELKKFKLYLG-IAEEL-------GQDKIPRGRMEMAGPLEMAQLMVAHMGTKEAWLLALSTFERIHRKDLWERGQGED--------------------------------LVRVTPSNGLC---SLESQST----CLSDVSPDAPRKDPQITYKDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPIWAQQKLLETGWEHSRTRGHQASPIQMETLFEPDEERPEPPRTVVLQGAAGMGKSMLTHKVMLDWADGRLFQDQFDYVFYISCRELNRSHTQCSVHDLLSSCWPEHGAPLEDLIRAPDRLLFIIDGFHELHPSFHDVQGP----WCHCWEEKRPTELLLGSLIRRLLLPQLSLLITTRPCALEKLHGLLEHPRHVEILGFSEAEREEYFYRYFHNTGQASQVFSFMRDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQT-SRTTTAVYMFYLLSLMQPKP-GTPTFKVPANQRGLVSLAAEGLWNQKILFEEEDLGKHGLDGAEVSTFLNVNIFQKGIKC----EKFYSFIHLSFQEFFTAMYCALHGRE------------------AVRRALAEYGFSERNFLAHTVRFLFGLLNEEMRCYLERNLGWTISPQVKEEALAWIQNKARSEGSTLQHGSLELLSCLYEIQEEDFIQQALSHFQVVVVRNLSTKMEHVVCSFCARYCRGTEVLHLYGSAYSTGAEDGPPEPPGAQTQSTHS-----QERNILPDIYSAYLSATICTNSNLIELALYRNALGSQGVRLLCQGLRHANCKLQNLRLKRCHISG--------------------------------------------------------SACQDLAAAIIANRNLIRLDLSGN-SIGVLGLELLCEGLQHPMCRLQMIQLRKCLLEAAAGRALASVLS-NNSHLVELDLTGNPLEDLGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMN-QSLMELDLGLNDLGDSGALLLCEGLRHPDCKLQTLRLGICRLGSDACAGVASVLQVN-TCLRELDLSFNDLGDRGLWLLGEGLRHQTCRLQKLWLDSCGLTSKACEDLSSVLGISQTLNELYLTNNALGDTGVRLLCKRLRHPGCKLRVLWLFG-MDLNKVTHRRMAALRVTKPYLDIGC-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q5R7-1", "uniprot_id": "NAL12_MOUSE", "id": "E9Q5R7-1", "name": "NACHT, LRR and PYD domains-containing protein 12", "aln": "----------------------------MLPSTARDGLYRLSTYLEELEAGELKKFKLFLG-IAEDL-------SQDKIPWGRMEKAGPLEMAQLMVAHMGTREAWLLALSTFQRIHRKDLWERGQGED--------------------------------LVRVTPNNGLC---LFESQSA----CPLDVSPNAPRKDLQTTYKDYVRRKFQLMEDRNARLGECVNLSNRYTRLLLVKEHSNPIWTQQKFVDVEWERSRTRRHQTSPIQMETLFEPDEERPEPPHTVVLQGAAGMGKSMLAHKVMLDWADGRLFQGRFDYVFYISCRELNRSHTQCSVQDLISSCWPERGISLEDLMQAPDRLLFIIDGFDKLHPSFHDAQGP----WCLCWEEKQPTEVLLGSLIRRLLLPQVSLLITTRPCALEKLHGLLEHPRHVEILGFSEEARKEYFYRYFHNTGQASRVLSFLMDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQT-PRTTTAVYMFYLLSLMQPKP-GTPTFKVPANQRGLVSLAAEGLWNQKILFDEQDLGKHGLDGADVSTFLNVNIFQKGIKC----EKFYSFIHLSFQEFFAAMYCALNGRE------------------AVRRALAEYGFSERNFLALTVHFLFGLLNEEMRCYLERNLGWSISPQVKEEVLAWIQNKAGSEGSTLQHGSLELLSCLYEVQEEDFIQQALSHFQVVVVRSISTKMEHMVCSFCARYCRSTEVLHLHGSAYSTGMEDDPPEPSGVQTQSTYL-----QERNMLPDVYSAYLSAAVCTNSNLIELALYRNALGSQGVRLLCQGLRHASCKLQNLRLKRCQISG--------------------------------------------------------SACQDLAAAVIANRNLIRLDLSDN-SIGVPGLELLCEGLQHPRCRLQMIQLRKCLLEAAAGRSLASVLS-NNSYLVELDLTGNPLEDSGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMN-QSLLELDLGLNDLGDSGVLLLCEGLSHPDCKLQTLRLGICRLGSVACVGIASVLQVN-TCLQELDLSFNDLGDRGLQLLGEGLRHQTCRLQKLWLDNCGLTSKACEDLSSILGISQTLHELYLTNNALGDTGVCLLCKRLRHPGCKLRVLWLFG-MDLNKKTHRRMAALRVTKPYLDIGC-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P59046-1", "uniprot_id": "NAL12_HUMAN", "id": "P59046-1", "name": "NACHT, LRR and PYD domains-containing protein 12", "aln": "----------------------------MLRTAGRDGLCRLSTYLEELEAVELKKFKLYLG-TATEL-------GEGKIPWGSMEKAGPLEMAQLLITHFGPEEAWRLALSTFERINRKDLWERGQRED--------------------------------LVRDTPPGGPS---SLGNQST----CLLEVSLVTPRKDPQETYRDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPMQVQQQLLDTGRGHARTVGHQASPIKIETLFEPDEERPEPPRTVVMQGAAGIGKSMLAHKVMLDWADGKLFQGRFDYLFYINCREMNQSATECSMQDLIFSCWPEPSAPLQELIRVPERLLFIIDGFDELKPSFHDPQGP----WCLCWEEKRPTELLLNSLIRKKLLPELSLLITTRPTALEKLHRLLEHPRHVEILGFSEAERKEYFYKYFHNAEQAGQVFNYVRDNEPLFTMCFVPLVCWVVCTCLQQQLEGGGLLRQT-SRTTTAVYMLYLLSLMQPKP-GAPRLQPPPNQRGLCSLAADGLWNQKILFEEQDLRKHGLDGEDVSAFLNMNIFQKDINC----ERYYSFIHLSFQEFFAAMYYILDEGEG-----------GAGPDQDVTRLLTEYAFSERSFLALTSRFLFGLLNEETRSHLEKSLCWKVSPHIKMDLLQWIQSKAQSDGSTLQQGSLEFFSCLYEIQEEEFIQQALSHFQVIVVSNIASKMEHMVSSFCLKRCRSAQVLHLYGATYSADGEDRARCSAGAHTLLVQL-----PERTVLLDAYSEHLAAALCTNPNLIELSLYRNALGSRGVKLLCQGLRHPNCKLQNLRLKRCRISS--------------------------------------------------------SACEDLSAALIANKNLTRMDLSGN-GVGFPGMMLLCEGLRHPQCRLQMIQLRKCQLESGACQEMASVLG-TNPHLVELDLTGNALEDLGLRLLCQGLRHPVCRLRTLWLKICRLTAAACDELASTLSVN-QSLRELDLSLNELGDLGVLLLCEGLRHPTCKLQTLRLGICRLGSAACEGLSVVLQAN-HNLRELDLSFNDLGDWGLWLLAEGLQHPACRLQKLWLDSCGLTAKACENLYFTLGINQTLTDLYLTNNALGDTGVRLLCKRLSHPGCKLRVLWLFG-MDLNKMTHSRLAALRVTKPYLDIGC-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A523-1", "uniprot_id": "NLRP3_RAT", "id": "D4A523-1", "name": "NACHT, LRR and PYD domains-containing protein 3", "aln": "----------------------------MKMMSVR---CKLAQYLEDLEDVDLKKFKMHLEDYPPEK-------GCVPIPRGQMEKADHLDLATLMIDFNGEEKAWGMAVWIFAAINRRDLWEKAKKDQPEWN----------------------------DACTSNLSMVCQEDSLEEEWIGLLGYLSRISICKKKKDYCKIYRRHVRSRFYSIKDRNARLGESVDLNRRYTQLQLVKEHPSKQEREHELLTIGR--TKMWDRPMSSLKLELLFEPEDEHLEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVS-LRAPKSLADLIISCWPDPNPPVCKILCKPSRILFLMDGFDELQGAFDEHIEE----VCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEILFTMCFIPLVCWIVCTGLKQQMETGKSLAQT-SKTTTAVYVFFLSSLLQSRG-GIEEHLFSAYLPGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDC----ERFYSFSHMTFQEFFAAMYYLLEEEEEGVTVRKGPEGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQRQPSQLELFYCLYEMQEEDFVQSAMGHFPKIEIN-LSTRMDHVVSSFCIKNCHRVKTLSLGFLHNSPKEEEEEK-----------------------------------------------RGSQPLDQVQCVFP-DPHVACSSR---LVNCCLTS--------------------------------------------------------SFCRGLFSSLSTNQSLTELDLSDN-TLGDPGMRVLCEALQHPGCNIQRLWLGRCGLTHQCCFNISSVLS-SSQKLVELDLSDNALGDFGVRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSN-HSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSLCCSALTSVLKTN-QNLTHLYLRSNALGDMGLKLLCEGLLHPDCKLQMLELDNCSLTSHSCWDLSTILTHNQSLRKLNLSNNDLGDLCVVTLCEVLKQQGCLLQSLQLGE-MYLNCETKRTLEALQEEKPELTVVFEISW-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4B8-1", "uniprot_id": "NLRP3_MOUSE", "id": "Q8R4B8-1", "name": "NACHT, LRR and PYD domains-containing protein 3", "aln": "------------------------------MTSVR---CKLAQYLEDLEDVDLKKFKMHLEDYPPEK-------GCIPVPRGQMEKADHLDLATLMIDFNGEEKAWAMAVWIFAAINRRDLWEKAKKDQPEWN----------------------------DTCTSHSSMVCQEDSLEEEWMGLLGYLSRISICKKKKDYCKMYRRHVRSRFYSIKDRNARLGESVDLNSRYTQLQLVKEHPSKQEREHELLTIGR--TKMRDSPMSSLKLELLFEPEDGHSEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVS-LRTPRSLADLIVSCWPDPNPPVCKILRKPSRILFLMDGFDELQGAFDEHIGE----VCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEVLFTMCFIPLVCWIVCTGLKQQMETGKSLAQT-SKTTTAVYVFFLSSLLQSRG-GIEEHLFSDYLQGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDC----ERFYSFSHMTFQEFFAAMYYLLEEEAEGETVRKGPGGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQWQPSQLELFYCLYEMQEEDFVQSAMDHFPKIEIN-LSTRMDHVVSSFCIKNCHRVKTLSLGFFHNSPKEEEEER-----------------------------------------------RGGRPLDQVQCVFP-DTHVACSSR---LVNCCLTS--------------------------------------------------------SFCRGLFSSLSTNRSLTELDLSDN-TLGDPGMRVLCEALQHPGCNIQRLWLGRCGLSHQCCFDISSVLS-SSQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSN-HSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSICCSALTSVLKTN-QNFTHLYLRSNALGDTGLRLLCEGLLHPDCKLQMLELDNCSLTSHSCWNLSTILTHNHSLRKLNLGNNDLGDLCVVTLCEVLKQQGCLLQSLQLGE-MYLNRETKRALEALQEEKPELTIVFEISW-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96P20-1", "uniprot_id": "NLRP3_HUMAN", "id": "Q96P20-1", "name": "NACHT, LRR and PYD domains-containing protein 3", "aln": "----------------------------MKMASTR---CKLARYLEDLEDVDLKKFKMHLEDYPPQK-------GCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSD--------------------------NARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQQEREQELLAIGK--TKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVS-LVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGP----LCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQT-SKTTTAVYVFFLSSLLQPRG-GSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDC----EKFYSFIHMTFQEFFAAMYYLLEEEKEGRTN--VPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEIN-LSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEE-----------------------------------------------KEGRHLDMVQCVLPSSSHAACSHG---LVNSHLTS--------------------------------------------------------SFCRGLFSVLSTSQSLTELDLSDN-SLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLS-SNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTS-HSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTN-QNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSE-MYFNYETKSALETLQEEKPELTVVFEPSW-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A1Z7N0-1", "uniprot_id": "A1Z7N0_DROME", "id": "A1Z7N0-1", "name": "Leucine-rich repeat-containing protein 34", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCDVLLPCEYNPKECPSPAAEKSRLFTILLLYCWQREYDKRPYRQFQFKRLTFEERIGRRYHCIRDLRIIVNYLLR-----------RPQLSVQISSLVV-SNWDAGLLKDFVRSLLPVWYIELRLMRFPREFFVMLRLNAAKMN-----VSQLSLEGTPLTDEDVRILREFLLVSKTLRR----LNVSSCS--------------------------------------------------------LTQFNFALIADGVYK----------SPGVRRLSANRLLGMSLS--------------------------------------------------------------------------------------------------------------------------------LDTEKISSVLSSLLMQN-------------------------------------------------------------------------------------------------------------------TLWALSLEHCELTAQDMIPIAEHLARTNSKFRRLRIACNKIGPDGAFFLLRGMS-MGGNLELLDLSYCSIGTHGGEWVAKYLASC-RRLQVLHLNYNDMGPTAVNLILLAMKK-QCKLEKLTLYGNHFDSRTAMIVRRLLDAE-VVLHSELDISYTYDEALQDYRVVPWR-----------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E7FA88-1", "uniprot_id": "E7FA88_DANRE", "id": "E7FA88-1", "name": "", "aln": "------MYCNYNMDNTRSSRDEDIYSCTSRESEEVLSNTSYWSLPSYFRHRKFHRSSVHEKISDSSESSRVSLKSDWSMNPPPLLGEERKSSNLNMSSLVSVRSDWSMDPPPLLRAKGKSAVSSGVSDN------------------------------------------------------IDWLVCSPYLRVERKSSALRHKLSLLKKFQCLYEGTAVQGKPTLLNEIYTELYITESESGEISHEHEVRQIETQ-SRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQD-VQLIFPLPFREIN--LIKDKKFSLVSLLQTFFTREIHLDMIQNSAVIFIFDGLDECRLPFNFSRNE----ILLDVTKETSVDVLLTNLIVGNLLPYALIWITSRPAAADLVPSECVHR-VTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILRLGKLAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLLFTNHNIN-----------VFEQMTKSFEGTPLNKSDLQSLTLNMELFEISEPVLTDVAAMCEMDWRVVNEISALHCKAVDEVLQNKNGHLDLFLRFLLGLSVECNQILLQRLTKQRRHLYN------DNKTVEYIKKKIRTINSPEKSISLFHCLN-----------------------------------------------------ELGDHSLVEEIQQYLTSGKIKEFKLSSSQWSAVA--------------------------------------------------------------FVLLTSEKKLEEFWLKEF-VGAETKADHVLQKLLPVVKESRKAELSKCGLTEECCAALASALRSKLSHVRELDLSGNKLGDSGIENLSTGLENLHCKLEILRLRSCGITAKGCTALASALRSNPEQIRQLDLSENNIRDWGVKHLFTELKNPDCKLEILGLRNCGITIEGCAALTSALIINPSHLRELDISRNSLGDTGQELLTSLLNSQHHKLEILLLHKFPMTFTSLPSSHSPEMFPQRFRTHNLKE------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: : : . . . : : : . . : . . : : * . : : * : * : * * : * : :: : . : * : * : . : : * : : . : : . ", "identical_positions": 9, "similar_positions": 41, "identity": "0.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-307", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AZ54-1", "uniprot_id": "HEMGN_RAT", "id": "Q6AZ54-1", "name": "Hemogen", "aln": "MDVRKDQSHLTLNQTPEAHVEKSHAPDIIGSWSLRNREQLKKRKAEAQGRQTSQWQLGEQKKRKYQRTGKGNRRGRKRQGNVEQKAESWSQ-TENERVQEVLVPAEEETEYSGNTATQALPLRASPTKAVPTEHCSEVPQESLQCQEITIQNHSQTHQRRDKAEALSPTTCQEIGVLQYSPKMCQDMAEPEARSPKMCQETAVPQTYSPKAHEDMAEYEALSPKMCRETPVPQYHSSKIPQDMTGPEALAPDMCQETTVSQNHSSKVPQDMAGPEALSLKMCQEPTVLQEHTLKICQDVARPDVLSSKTHQEMTVPKALPCITPGDAAGPEGCSPKTLPQS--------DVTPMSVTPGKNTSHPDLGTAVAEGCFSEAGECIVSEDISTKTHQEAVEPKFLSHKTYKEFTVPIVSSHKTIQESPGPEEYSPG--------------SRHEMS----------------------------GPEDLSIKTCKNRDGPKHSLPEGAQEVGGAQRQDPDAQDIEDAGAFSQD---LEEGNKADQDPETPAGPQGPQKICPENDVHSSALF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ERZ0-1", "uniprot_id": "HEMGN_MOUSE", "id": "Q9ERZ0-1", "name": "Hemogen", "aln": "MDMGKGRPRLKLPQMPEAHPQKSCAPDIIGSWSLRNREQLRKRKAEAQGRQTSQWLLGEQKKRKYQRTGKGNKRGRKRQGNVEQKAEPWSQ-TERERVQEVLVSAEEETEHPGNSATEALPLVPSPTKAVPADQCSEAHQESIQCQERAIQNHSQTH--------LSPTTCQGIAVLQHSPKMCQDMAEPEVFSPNMCQETAVPQTYPPKALEEMAAAEPLSPKMC----------------------------QETTVSPNHSSKVPQDMAGPEALSPNMCQEPTVPQEHTLKMCHDVARPEVLSPKTHQEMAVPKAFPCVTPGDAAGLEGCAPKALPQSDVAEGCPLDTTPTSVTPEQTTSDPDLGMAVTEGFFSEARECTVSEGVSTKTHQEAVEPEFISHETYKEFTVPIVSSQKTIQESPEPEQYSPETCQPIPGPENYSLETCHEMS----------------------------GPEDLSIKTCQDREEPKHSLPEGAQKVGGAQGQDADAQDSENAGAFSQDFTEMEEENKADQDPEAPASPQGSQETCPENGIYSSALF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXL5-1", "uniprot_id": "HEMGN_HUMAN", "id": "Q9BXL5-1", "name": "Hemogen", "aln": "MDLGKDQSHLKHHQTPDPHQEENHSPEVIGTWSLRNRELLRKRKAEVHEKETSQWLFGEQKKRKQQRTGKGNRRGRKRQQNTELKVEPQPQ-IEKEIVEKALAPIEKKTEPPG-SITKVFPSVASPQKVVPEEHFSEICQESNIYQEN-------------------FSEYQEIAVQNHSSETCQHVSEPEDLSPKMYQEISVLQ--------------------------------------------------------DNSSKICQDMKEPEDNSPNTCQVISVIQDHPFKMYQDMAKREDLAPKMCQEAAVPKILPCPTSEDTADLAGCSLQAYPKPDVPKGYILDTDQNPAEPEEYN-ETDQGIAETEGLFPKIQEIAEPKDLSTKTHQESAEPKYLPHKTCNEIIVPKAPSHKTIQETPHSEDYSIEINQETPGSEKYSPETYQEIPGLEEYSPEIYQETSQLEEYSPEIYQETPGPEDLSTETYKNKDVPKECFPEPHQETGGPQGQDPKAHQEDAKDAYTFP---QEMKEKPKEEPGIPAILN---ESHPENDVYSYVLF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6Y2-1", "uniprot_id": "A0ACD6B6Y2_DANRE", "id": "A0ACD6B6Y2-1", "name": "", "aln": "------MEDPLEKEIPPTEIKDSDEGGIR--RRLRDRDLLKKRKAEAEEKATNQWVYGAQSIKRVKKRTTTGTPGRKGRPRKEPIVIAEDLGLAQEVDPSPITIPVTEPELPTIAEIEPLQPVEPQQELVPEEAISEKPQE-------------------------------EFLIEDLGPDEEEDMPQ---------------------------------------------------------------------------KNLVIDTGDDE------------------KPYNDVPEQ--------SSIAIPMFAPAPDSSQPDNLSLTENLLF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .. :.. : **:*: *:*****.. : *.** * *. :: :: . . *** : . * . . .* . :. :.* . : : : . : ** : ** ** : : : ... :.:.: .:: * * * :*:.. .. ::* *. . :. . ", "identical_positions": 33, "similar_positions": 65, "identity": "5.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-308", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CAT8-1", "uniprot_id": "FBX48_MOUSE", "id": "Q8CAT8-1", "name": "F-box only protein 48", "aln": "MKKTSKKNNNFKIPGTELNSADAERGKEESQRNFVELLPLEVTYKIFSQLDIQSLCRASRTCTGWNCAIRNNDSLWKPHCLTIRAVCQREIDDDIKSGYTWRVILLRNYQKSKVKYEWLSGRYSNIRSPVNLPEKAMCPMDADTWGEILDAELEREVEKLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5FWF7-1", "uniprot_id": "FBX48_HUMAN", "id": "Q5FWF7-1", "name": "F-box only protein 48", "aln": "MHKNSKRNNNLRVSHTEANSVDAEKEKNESQNNFFELLPAEITFKIFSQLDIRSLCRASLTCRSWNDTIRNSDSLWKPHCMTVRAVCRREIDDDLESGYSWRVILLRNYQKSKVKHEWLSGRYSNICSPISLPEKIMYPMDADTWGEILEAELER------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "R4GEA9-1", "uniprot_id": "R4GEA9_DANRE", "id": "R4GEA9-1", "name": "", "aln": "MSVEGAAAPSAGQKLTRWCCSGLQDP-LQIERDFSEALPAEMSVRIFGELDVRSLCRASVTCKHWNDIIEGSDHLWRSHCLTGLAVCRREVNGDRLDGCSWKVTLVRNYRKGCVKRRWLKGRYSNIRSADELPANSMCPLDVETWGEILEAELER------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . *. . . : : :.:* * ** *:: :**.:**::****** ** ** *...* **:.**:* ***:**::.* .* :*:* *:***:*. ** .**.****** *. .** : * *:*.:******:***** ", "identical_positions": 69, "similar_positions": 42, "identity": "42.86%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-317", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96CN5-1", "uniprot_id": "LRC45_HUMAN", "id": "Q96CN5-1", "name": "Leucine-rich repeat-containing protein 45", "aln": "--------------------MEEFRRSYSRLCRESGAEPQEAVLQQLHQLP----RGRLDLATQSLTVETCRALGKLLPRETLCTELVLSDCMLSEEGATLLLRGLCANTVLRFLDLKGNNLRAAGAEALGKLLQQNKSIQSLTLEWNSLGTWDDAFATFCGGLAANGALQRLDLRNNQISHKGAEELALALKGNTTLQQLDLRWNNVGLLGGRALMNCLPSNRTLWRLDLAGNNIPGDVLRAVEQAMGHSQDRLTTFQENQARTHVLSKEVQHLREEKSKQFLDLMETIDKQREEMAKSSRASAARVGQLQEALNERHSIINALKAKLQMTEAALALSEQKAQDLGELLATAEQEQLSLSQRQAKELKLEQQEAAERESKLLRDLSAANEKNLLLQNQVDELERKFRCQQEQLFQTRQEMTSMSAELKMRAIQAEERLDMEKRRCRQSLEDSESLRIKEVEHMTRHLEESEKAMQERVQRLEAARLSLEEELSRVKAAALSERGQAEEELIKAKSQARLEEQQRLAHLEDKLRLLAQARDEAQGACLQQKQVVAEAQTRVSQLGLQVEGLRRRLEELQQELSLKDQERVAEVSRVRVELQEQNGRLQAELAAQEALREKAAALERQLKVMASDHREALLDRESENASLREKLRLREAEIARIRDEEAQRASFLQNAVLAYVQASPVRTLSPPK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GWK1-1", "uniprot_id": "A0AC58GWK1_DANRE", "id": "A0AC58GWK1-1", "name": "", "aln": "MNKFLFFTQIFSACVEAAGGMEDFRRSYLRLCKEGGVDTQESVLAQLHDTRTVTGSSRLDLRGQSITVDTCSVLARVLQNDTVFTEIILSDCMLSEEGVKMLLNGLCSNTTVKVLDLKGNNMRGTGAEALGQLLVRNKVLRRLVLEWNALGMWEEGFAVFCEGLASSTSLTQLDLRNNQINHQGAAELCVALKRNSNLQELDLRWNNMGLLGGRSLLEAMQQNRTLTKLELAGNNIPSDTLRAIEQSMNHNVDRQSTLQESKSRTQVLSKEIQLLKDEKSRQYLSLMETIDRQKGEMGRSSRNSSIRLGQLQEALNEQKSSVNSLTAKLQMTEAALALSEQKNHDLADLLTRVKMEKNELRERQSREIKKEHEENAVREAKHLKEVNSLSEKNLQLRSKLEETERRCKTQQDQIFELKQELTNTTAELKLRLAQTEERLEMEKRRAKQALEDMDGLRQKEVDHLTRHQEDSERALQERILKLEGQRIQLEEELSRVKASLVTERAQAEEELGKVRSQVRLEEQQHLTSLEEKLRAVRQSRDESQNHCTQQKQTIAELHAKVSQQSIETDSLRRRIDELQQDLAGKEQEKVSEVTRVRVELQEQIGHLQAERTAQGGLKEKIAALEREIKALSVAHREALLDKESEMSSLLERLRIREGEIQRIREDEAQRASFLQNAILTYVQGSPLAHFSPKK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:***** ***:*.*.:.**:** ***: .**** **:**:** .*.::* .:*: **::**********..:**.***:**.::.*******:*.:******:** :** :: *.****:** *::.**.** ***:. :* :********.*:** **.:*** *:.**:*******:******:*::.: .**** :*:*******.*.***:**:*.*. ** :*:**.::**:*****:* *::***:*:*.******:*: **.:*** *: *:*********::* :*:*.**************** :**.:**: .: *: .* :**::*:* *::* * **:* *:::.: .**** *:.:::* **: : **:*:*: :**:*. :****:* *:****:*****.:*:*** :.** ***:*:*** *:**:*:***: :**. *:.**********: ::**.****** *.:**.******:*: **:*** : *:***:*. * ****.:** :::*** .::.:.****::****:*: *:**:*:**:********* *:**** :** .*:** *****::*.:: *******:*** :** *:**:**.** ***::***********:*:***.**: :** *", "identical_positions": 399, "similar_positions": 198, "identity": "57.49%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-328", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R5I7-1", "uniprot_id": "MYCD_RAT", "id": "Q8R5I7-1", "name": "Myocardin", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLLGSEHSLLIRRKFRSVLQLRLQQRRTQEQLANQGLIPPLKSPTEFHDPRKKLDSAKTEDSLRRKVRNRSDRASLVNMHILQAS--TAERSIPTAQMKLKRARLADDLNEKIALRPGPLELVEKNILPMDSSVKEAIKGTEVSLSKAADAFAFEDDSSRDGLSPDQARSEDPQGSGGSTP--------------DIKSTEAPLAGPLDTIQDLTPGSESDKNDTASQLSNQSDSGKQVLGPLSTPIP-------------------------------------------------------------------------VHTAVKSKSLGDSKNRHKKPKDPKPKVKKLKYHQYIPPDQKAEKSPPP---MDSAYARLLQQQQLFLQLQILSQQQQQQQQQQQQQQQQQQQQ-RFSYPGMHQAHLKEPNEQMTRNPNSSSTPLNNTP-------------------------------------------LSPVKNSLSGQTGVSSLKPGPLPPN---------------------------LDDLKVSELRQQLRIRGLPVSGTKTALVDRLRPFQ-----DCAGNPVPNFGDITTV-----------------------------------------------TFPVTPNTLPSYQSSPS------------------------------------------------------------GFYHFGSTSSSPPISPASSDLSAAGSLPDTFTDASPG-FGLHASPVPACTDESLLSSLNGGSGPSEPDGLDSEKDKMLVEKQKVINQLTWKLRQEQRQVEELRMQLQKQK-SGCNDQKPLPFLATTIKQE--------------------------------DVSSCPFAAQQASGKGQGHSSDSPPPACETAQLLP-------------------HCVESSGQTHVLSSTFLSPQCSPQHSPLGTLKSPQHISLPPSPNNHYFLASSSGAQRENHGVSSPNSSQGC-AQMTGLQSSDKVGPTFSIPSPTFPK--SSPTVPEITQ-PPSYEDAVKQQMT--------------------------------------------RSQQMDELLDVLIESGEMPADAREDHSC------------------------------LQKIPKIPGSSCSPTTILPKSSASFEQASSGGQISFDHYATDSEEHLEVLLNSHSPIGKVSDVTLLKIGSEEPP----------------------------------------FDGIMDGFPGKAAEDLFSAHELLPGPLSPMHTQLSPPSVDSS-----------GLQLSFTESPWETMEWLDLTPPSSTPG--FSNLTSSGPSIFNIDFLDVTDLNLNSPMDLHLQQW--------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VIM5-1", "uniprot_id": "MYCD_MOUSE", "id": "Q8VIM5-1", "name": "Myocardin", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLLGSEHSLLIRRKFRSVLQLRLQQRRTQEQLANQGLIPPLKGPTEFHDPRKQLDSAKTEDSLRRKGRNRSDRASLVTMHILQAS--TAERSIPTAQMKLKRARLADDLNEKIALRPGPLELVEKNILPMDSSVKEAIKGTEVSLSKAADAFAFEDDSSRDGLSPDQARSEDPQGSTGSTP--------------DIKSTEA----PLDTIQDLTPGSESDKNDAASQPGNQSDPGKQVLGPLSTPIP-------------------------------------------------------------------------VHTAVKSKSLGDSKNRHKKPKDPKPKVKKLKYHQYIPPDQKAEKSPPP---MDSAYARLLQQQQLFLQLQILSQQQQQQQQQQQQQQQQQQQQQRFSYPGMHQTHLKEPNEQMARNPNPSSTPLSNTP-------------------------------------------LSPVKNSISGQTGVSSLKPGPLPPN---------------------------LDDLKVSELRQQLRIRGLPVSGTKTALVDRLRPFQ-----DCAGNPVPNFGDITTV-----------------------------------------------TFPVTPNTLPSYQSSPT------------------------------------------------------------GFYHFGSTSSSPPISPASSDLSAAGSLPDTFTDASPG-FGLHASPVPACTDESLLSSLNGGSGPSEPDGLDSEKDKMLVEKQKVINQLTWKLRQEQRQVEELRMQLQKQK-SSCSDQKPLPFLATTIKQE--------------------------------DVSSCPFAPQQASGKGQGHSSDSPPPACETAQLLP-------------------HCVESSGQTHVLSSTFLSPQCSPQHSPLGGLKSPQHISLPPSPNNHYFLASSSGAQRENHGVSSPSSSQGC-AQMTGLQSSDKVGPTFSIPSPTFSK--SSSAVSDITQ-PPSYEDAVKQQMT--------------------------------------------RSQQMDELLDVLIESGEMPADAREDHSC------------------------------LQKIPKIPGSSCSPTAIPPKPSASFEQASSGGQMAFDHYANDSDEHLEVLLNSHSPIGKVSDVTLLKIGSEEPP----------------------------------------FDSIMDGFPGKAAEDLFSAHELLPGPLSPMHAQLSPPSVDSS-----------GLQLSFTESPWETMEWLDLTPPSSTPG--FSNLTSSGPSIFNIDFLDVTDLNLNSPMDLHLQQW--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IZQ8-1", "uniprot_id": "MYCD_HUMAN", "id": "Q8IZQ8-1", "name": "Myocardin", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLLGSEHSLLIRSKFRSVLQLRLQQRRTQEQLANQGIIPPLKRPAEFHEQRKHLDSDKAKNSLKRKARNRCNSADLVNMHILQAS--TAERSIPTAQMKLKRARLADDLNEKIALRPGPLELVEKNILPVDSAVKEAIKGNQVSFSKSTDAFAFEEDSSSDGLSPDQTRSEDPQNSAGSPP--------------DAKASDTPSTGSLGTNQDLASGSENDRNDSASQPSHQSDAGKQGLGPPSTPIA-------------------------------------------------------------------------VHAAVKSKSLGDSKNRHKKPKDPKPKVKKLKYHQYIPPDQKAEKSPPP---MDSAYARLLQQQQLFLQLQILSQQQQQQQH-------------RFSYLGMHQAQLKEPNEQMVRNPNSSSTPLSNTP-------------------------------------------LSPVKNSFSGQTGVSSFKPGPLPPN---------------------------LDDLKVSELRQQLRIRGLPVSGTKTALMDRLRPFQ-----DCSGNPVPNFGDITTV-----------------------------------------------TFPVTPNTLPNYQSSSSTSAL------------------------------------------------------SNGFYHFGSTSSSPPISPASSDLSVAGSLPDTFNDASPS-FGLHPSPVHVCTEESLMSSLNGGSVPSELDGLDSEKDKMLVEKQKVINELTWKLQQEQRQVEELRMQLQKQKRNNCSEKKPLPFLAASIKQEE-------------------------------AVSSCPFASQVP-VKRQSSSSECHPPACEAAQLQPLG---------------NAHCVESSDQTNVLSSTFLSPQCSPQHSPLGAVKSPQHISLPPSPNNPHFLPSSSGAQGEGHRVSSPISSQVCTAQMAGLHSSDKVGPKFSIPSPTFSK--SSSAISEVTQ-PPSYEDAVKQQMT--------------------------------------------RSQQMDELLDVLIESGEMPADAREDHSC------------------------------LQKVPKIPRSSRSPTAVLTKPSASFEQASSGSQIPFDPYATDSDEHLEVLLNSQSPLGKMSDVTLLKIGSEEPH----------------------------------------FDGIMDGFSGKAAEDLFNAHEILPGPLSPMQTQFSPSSVDSN-----------GLQLSFTESPWETMEWLDLTPPNSTPG--FSALTTSSPSIFNIDFLDVTDLNLNSSMDLHLQQW--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BGQ6-1", "uniprot_id": "A0A8M2BGQ6_DANRE", "id": "A0A8M2BGQ6-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTLLSSEHSVLIRSKFKSVLQLRLQQRRTREQISDQAVMPPLKSPAAFHEQRKNLERSKNGDYLKHKIRSRSEKSELANMRILHD----GEGPTADTHSRLKRARLT-----------------EQNMSPLQEDTDTVNDGLQQ------DSYTFEEDSSS-----EESLLEN-KSSGSCSP--------------TADSSRQ-------------HGSQSKDGSSQNQDENMTKSQE------NPPVP-------------------------------------------------------------------------VPAIVKSKMS--EKNRHKKPKDMKPKVKKLKYHQYIPPDQKAERSPAPQ--MDSAYARLLQQQQLFLQLQILSQQKQQMQTQQTQMQTQTQQSFSYHTLGPHTHKQVSEAQASCSSSVHTSTSSSSSS-------------------------------------------SSPEKNSYC--SSISPVRPAPLPTN---------------------------LDDLKVSELRQQLRVRGLPVSGTKTALIQRLRPFR-----DSGCGSPLGPVDPSSS-----------------------------------------------TFPAS-----SFQPPPP----------------------------------------------------------SAGLHPFCS--STPPVSPASSDLSIS---ADSFSDATVSPFGTQPSPAHTEHTP------------------DAEKDKMLLEKQKVIEELMWRLQQEQRQVEELRTQLHRRR-LEPHAHTHTPFCSAVVKQE--------------------------------PLSSSCVELQTSGGVCAFLSPQCSP--QESPLNKP--------------------CSSPQSTHTSPAHTHLLTHTLNHNNTSGSRGSIQHQQKSSAPP---LSCSYSSEQRSVQLYCSPSEHSISSRAAAKSRSAAPQREARSPSSPAIFC--SSDCPASVSKRPPCYQDAVKQQMV--------------------------------------------RSQQMDELLDVLIESGVSPSGGRFHR---------------------------------------------------------------------PYDAHTDVQLEALLHRTHSQTHT----------------------------------------------------------------QTHTDPSAPAELLMEPLSPSAGKLA--VLEAQ-----------GLGLGFCESPWESMEWLDLTPPGSTFQSAVPPAATHTHNIFSSEFLDAADISLN------LDQW--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z043-1", "uniprot_id": "B7Z043_DROME", "id": "B7Z043-1", "name": "", "aln": "MPVIADAASDEPPAKCCKHCEESTQSVDGGPASWRLTLDQDLIDTLKGNFPSWFQGSAGGGGGAGGAASKQNPQQHNHQLAQQKHHQLVATSVIPITIDTKLAASNTNTLQQHQQQTAILGHSSSSASPASSVSSNSSKKSISSSLSSCSSSSSNSSSCGSNHCNSKSVSSGAKGAGSATASRFLNKSTSTSPTKSLSRTLKATQKPNGNHKVGQLVKSASLHSLSSGSSGSSSGNSASGSSSLLATISTSPLTTVELISSAACSGLLATRLSGKDLEHSFQDIILLHEAYDDMSEGEQRLHATFLGSSDDGNNSDCYDARQSPPKAIVDSSPLQPAMDKNKESLKVKLMVRRPHSQLVEQGIIPSLKTSPAIHEQCKQLERAKTSDLLKAKIQQRPNREDLERLHILEEDECHIDPSLAEKQRMLKKARLADQLNSQIQHRPGPLELIKKNILHTEKPIEKIVKEGLVSFKATSEGLLTRPQHPHSYVTFDDDSLSSESDTRQTPPRLDEAMVATSSSPTDVLQAAAASAGIVTMALTMPTAGQLVVTSPQILPQQQQPKAIVVPAPVPPPPPPPPPLPMASIIKVKQETANLYEELCQSVTGTTASPVNHLYSPCSLASSTSTLSPLSSIASPPPPPMTTTRLHLAPVSVKSDAPGKDKNRKKSKSKPVSKARTIKFHEYKGPPSAAGQKQDQTQPEETSYQLMLEQQNCLLKFLENLNKNQSIIPAPSAPGVMLPAAPGATNNSITVTTKTVPALASQSAPAPAPISLPNTISITSSSGGAPLNFGDATMLTPTPAATPTPPTLSLIAAPQQQLQLHQQHQQLHQPTPVQHPPPLPSPALSVSSSIPPSPATSYAESTTSSITDLARLEKMKVSDLKQHLKRRNLPVSGPKPHLIERLKPYLPLEPLDSNVTPAPTSNNSNTTPEVITISDAMDTSNCGLLEQPPPVTMLVSDASMEHEQMDVVQQQMDNTHPMTLQTILPPQPQTATIILTNEELLREQQRKIDELQRQLQRSQQELQKIRQRQQQQQHQQQQTVTAQVVNALPSQQITLITTTSNGPQQTLTVMPQQVEKNFPAKVTVKATG--GNSNHKVNGLQQQGSAAKKPASSNSNSNSNISSSNPPPINQKMVVKQQLEAKIQKQKAAAAAAAQQQQQQQQQQQQQQQQQALQQQQQQQQQQQQVRLLTQKTQTVFIPFNNNNHINNASAKTTTKKSNVPANNTNTTTATMMQAAKPAAVAAAAASPGNQHHNNLGLLWNEGNQTILLLGLNDQHMTAHTLGNISLTATTTTTAAPPAATPVAASTIAPPKKILNGHQRTNSLPSIVFPIETKSIITQQQLQQLQQQQQQQQQFQPVQQPKQQQLNQVDIKPAPAPPPQYEEATKQLAASKAAALNGLLPLVKIKEEPVQSPAPSAAPLPQTAPLCKRKTASIKSEQVSDVLDILIKQGELPESAALEPITPLTPLPELSMFNGATPTTAAGGASIVPLVPKLETPVTPVQNLDVAMDTNVQHVGFASNQAPNHVFIESIDMASPLQTDSSAIDAESVAKTLDIFLEQHHATPPPSTPPKSCHSGSEKPNSPDAKLNHFDEYELLELMSQQLEMDMGDDSSGYCHASAAKSSNNNGNLRRDLNPSLQPSINELLDASSPDNVLLNNNTGADVDFDADSFVAQLSQHVTGNGNSPGVNCNGSIESSSSAVNSHFGSHSTPMDCDDFESTLNSFMQAVTQPQAGQHVEYATSTSMANGTGGGMGVDNGTGGAVDAFNASGDIFDLFNMDDYKMNWAAGDFTV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::.*. * :. *:::* **.:.*: :*.::*.** .. :*: *:*: * : *: * :.* : .* ::**. : . . : **:***: ::*: :. . . :. . : . :: .. ..: .* : ..: .. : .* . . . ***. .***:*. .. .*.:.:*:*:* * . * :. :::* :*:**: :*:: :::*. . . :. . .: ::. : :. * * *. *:.:***:*:*:*: *.*****.*. *::**:*: *. . : .: *.* : *. .. : : : . * : : . . ... : . * . .:.: : :* * ::* :::::: . * :::: : .: :*: ... . : . . * :. * .. . .. . : . :* : . . :. . . . .. . ** *::*.** . :*:*:.::**:**:.* * .. . : : : . : : . * *.* :::. * :.* ..: : .:* ..: . .. .* . : *:.: ", "identical_positions": 105, "similar_positions": 253, "identity": "5.87%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-33", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VS77-1", "uniprot_id": "MTH6_DROME", "id": "Q9VS77-1", "name": "Probable G protein-coupled receptor Mth-like 6", "aln": "--------------------------------------MLLNILAIILVFVIS---------------SQSEAVIPGCDYFDTVDIS----HIPKLNDSYAYEELIIPAHLTGLYTFRQ--------LADGSQEPVKS-HLRACICKLKPCIR-----FCCPRNKMMPNSRCSDGLTENLKR-INPYLKI------------TLEDGTIGKYYLLTDMIVLRYEFRYCEKVVSVQ--------------------------------EDQYKLYENGSFMIKP--------------DVNWTLSKQ------WYCLHPRLED---PNSIWILEHVYIPKSMPAVPQVGTIS---------------------------------------MVGCILTIAVYLYIKKLRN----LLGKCFICYVFCKFVQYLIWAGGDLN-LWNN------------ICSLAGYTNYFFALASHFWLSVMSHQIWKNLR--------------------------------------------------------------------LINRDERSYHFLIYNIYGWGTPA------------IMTAITYLVDWAWEDRPDKLNWIPGVG-LYRCWINTYDWSAMIY-LYGPMLILSLFNVVTFILTVNHIMKIKSSVKSSTQQQR---KCIQNN---------------DFLLYLRLSVMMGVTGISEVITYFVK-RHKFWRQVLR-VPNFFHLGSGIVVFVLFI-----------------------------------------------LKRSTFQMIMERISGPRRQQPAS-----------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VSE7-2", "uniprot_id": "MTH7_DROME", "id": "Q9VSE7-2", "name": "Probable G protein-coupled receptor Mth-like 7", "aln": "------------------------------------MRLPWVIFCTVLLLIFT---------------NNSNADIPGCNYYDTVDIS----YIERQNDSYLYDDIEIPASLTGYYEFRQ--------FGDGSITPIEK-HLRACVCSVRPCIR-----ICCPAKNFLANGKCDDGLKEELAR-FKPYIYF------------TYMD--LQARVPLTDMAIIRDEFFDCDEMIYIS--------------------------------DFNYFLEEVSIQIFNKCGLIVWFQDGKFWVTVDLFMEKQ------DYCLYRHNFDSDFPKSMWIIRHRCTSHISPGSLEILIIT---------------------------------------MICFVLTIAVYLYIKKLRN----VTGKCIVCCIVSRFIQCLIMILDHLN-LLNG------------ICSPAGYSSHFFRMASNLWLSVISYHTWKVLT--------------------------------------------------------------------SLNRVDPNYRFLRYNAFVWSTAA------------IMTGSIYIVNQIWENDPSKWNWLPLVG-FIRCSVKDWHPSVWIY-ISGPSLALSTFNVAMFALTAIYIRKVKGGINKFTNEEEGRINCINFDSQ-------------TYLQFLRLSIVMGLTWIFNVIPYSAR-LHIFWEWVGI-ISEYFHSAFGIVLFVLLV-----------------------------------------------LKRSTWTLMMDS----------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P83119-1", "uniprot_id": "MTH12_DROME", "id": "P83119-1", "name": "Probable G protein-coupled receptor Mth-like 12", "aln": "------------------------------------MFLWLKCFCTLIIVTIA---------------KNSSAKIPHCKYDETINIS----HFKRLNDAYIYEHFEIPANLTGEFDYKE--------LMDGSKVPTEFPNLRGCICKVRPCIR-----ICCARKNILSNGECSDGVKNEIKL-TMLDLTMQDILL----TDPTLAELNMIPQYNSTELLILREQFQPCDEIVSLK--------------------------------RDEYTILKDGSILLHT---------------SAEILSND------QYCLYPEIYS-DFPETIRIINRRCYRNVMPGIAQLSVIS---------------------------------------VVGFILTLAVYLSVEKLRN----LLGKCLICSLFSMFMEYFIWTMDYFR-LLQS------------ICSAAGYMKYFFSMSSYLWFSVVSFHLWELFT--------------------------------------------------------------------SLNRHEPQYRFLIYNTFVWCTAA------------IPTVVIFSMNQMWENDPGKSEWLPLVG-YFGCSVKDWNSSSWFY-SHIPIVILNSFNVIMFVLTAIYIWKVKKGVKSFAQHDERNTTCLEFNVQ-------------TYIQFVRLFLIMGASWLLDQLTRLAEDSHLLLDTIVLNLTVYLNAAFGILIFVLLI-----------------------------------------------LKGSTFKMIMER----------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "V9H0I1-1", "uniprot_id": "V9H0I1_DROME", "id": "V9H0I1-1", "name": "", "aln": "--------------------------------------MKLQLLGTFLVLILL---------------QFQAVNT---DSNKTEEDS----CVKSDDDNSNDED------------------------------------------DLWHCIP-----ICCPRKNMMANGGCS--FKEHLFR-TKLDLNIR-------------LDDNSTEALYFNNQTLLITSFWDIDEMMGLR--------------------------------RDEYTLYKNGTIYIHS---------------DQSIQTKE------EYCFYPHQIYSDFPETIWIISHKFSSIESPGAFELASGS---------------------------------------IICYIIIFGIYLFVKELRN----DFGKCVMSCVFCLFLDYLIWLMDELR-LLDD------------FCSLTGYIMFFFDFANSVWFSIISYCIWKKIT--------------------------------------------------------------------SVVSQENRDQFVFYSTFAYGISA------------IPLGIIISINQFWEEDLRKWNWLPLVG-FSRCSVDDCKRSSWVY-YFVPYAIMCAINIIMFVLTIKHIMKTKRNLHNLTKRPDRNETCVTVNFLN----FE------LYLLFLRISGIMGVAWIL-IIFLLIEVNSTFWDIFGI-IIQQIHYGFGIILFVLLI-----------------------------------------------FKRSTHQLLIAK----------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0R5-1", "uniprot_id": "MTH10_DROME", "id": "Q9W0R5-1", "name": "Probable G protein-coupled receptor Mth-like 10", "aln": "----------------------MPKKIHQPGGSLYCGVTLLGVLCLVVFRLIPGIPFGTYVMAERDHYHTIDDPNVPCNFYDTVNLTG---HRLFPNGSYDYYGTIVPAELVGTYDYIH--------SSLTERIEVRE-HVRGCVCKFKSCLN-----ICCPWRQVFNSEVDGCIIDHSDNR-TWPDPPMLN-----------ITFRNESTILVNMFTQFAIQSFRPCPKMFSLQPETN---------------------------NWDDYLLFENGSMLRVD---------------DKLLIRKN------EFCMVPTYVN---ESDMFYTIHPANCDMQDDHSTVKIINSYAMMF--------------------------------SIPFMMLTIAVYLLIPELRN----QHGKSLVCYLIGLSVGYSSLCYVQLY-QVDATGV---------TCKVFGYTAYFFFMGAYMWLSVISFDLWHNFRGT-----------------------------------------------------------------RGINRFQEKKRFLFYSLYSWGIAL------------VFLAFTYCAQQLTN---LPANLKPGIGDGVYCWLDMSNWAAMIY-FYGPILAIVVANTIMFIMTAIKIHGVQREMARIIASENSTKNLRTEKDKR----FYRAWSNYRFGLFLRLFLIMGITWLTELISYFVG-SDKGWSKLFY-ISDLANAMQGFLIFMLFV-----------------------------------------------MKKKVKHLITNRCSSVRDGSNQRQSQYSTKTTSSSVANLSLHEKPSVEKPLVISSSVDPQKTTIFR----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0R6-1", "uniprot_id": "MTH9_DROME", "id": "Q9W0R6-1", "name": "Probable G protein-coupled receptor Mth-like 9", "aln": "------------------------------------MVSPLIILLIIWLSVGAKS-------------VEIASINHPCAYAHTVNITD---GLRMKDGSYSYAGVVVPPHLMAEYSFKV--------IDGVEYRAKKH--LRGCVCLLKPCIS-----FCCPENLVFDAKHWNCTMPHQVRESTHVELTYAN---------------RTVDQVRIRDRFVVRTELGCRNKFVDKKHDN-----------------------------FWQWDLFENGTLRRDN-----------------RLWSTD------EYCFSPLEHN---PEQWELTPLNCERFQTGYRVWIYAICS--------------------------------------IIAIIINIFILSLLGSVRDARKSHYGQLIIYYLLSMIVGYSLLVYLALKNPMKLSHV---------ACRNIGFLAYFCIMLSFVFLAICSLDFLLKFK--------------------------------------------------------------------------QKAVRSSVRRLSLALAV------------LAVIGLRFLVSLAQDSKLPKHFKPGMG-EDYCWFDVRTWGILIY-YYGPIALLLIFSIVCCLKAYFSIYELPPDTQYILGTQLKIVKTHFYAFSA----YIVG-VFAVWIREIVVYIMARVREHFFIIDFWSGICILGLAIAGFILLLGKNLHVKSWWAINVE-----------------------------------------------SSQTDLSIINARVYKFDEKGDLKSSDSPYKPTVTSL----------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q14246-1", "uniprot_id": "AGRE1_HUMAN", "id": "Q14246-1", "name": "Adhesion G protein-coupled receptor E1", "aln": "MRGFNLLLFWGCCVMHSWEGHIRPTRKPNTKGNNCRDSTLCPAYATCTNTVDSYYCACKQGFLSSNGQNHFKDPGVRCKDIDECSQSP---QPCGPNSSCKNLSGRYKCSCLDGFSSPTGNDWVPGKPGNFSCTDINECLTSSVCPEHSDCVNSMGSYSCSCQVGFISRNSTCEDVDECADPRACPEHATCNNTVGNYSCFCNPGFESSSGHLSFQGLKASCEDIDECTEMCPINSTCTNTPG-----------SYFCTCHPGFAPSNGQLNFTDQGVECRDIDECRQDPSTCGPNSICTNALGSYSCGCIAGFHPNPEGSQKDGNFSCQRVLFKCKEDVIPDNKQIQQCQEGTAVKPAYVSFCAQINNIFSVLDKVCENKTTVVSLKNTTESFVPVLKQISTWTKFTKEETSSLATVFLESVESMTLASFWKPSANITPAVRTEYLDIESKVINKECSEENVTLDLVAKGDKMKIGCSTIEESESTETTGVAF--------VSFVGMESVLNERFFKDHQAPLTTSEIKLKMNSRVVGGIMTGEKKDGFSDPIIYTLENIQPKQKFERPICVSWSTDVKGGRWTSFGCVILEASETYTICSCNQMANLAVIMASGELTMDFSLYIISHVGIIIS-LVCLVLAIATFLLCRSIRNHNTYLHLHLCVCLLLAKTLFLAGIHKTDNKM----GCAIIAGFLHYLFLACFFWMLVEAVILFLMVRNLKVVNYFSSRNIKMLHICAFGYGLPMLVVVISASVQPQGYGMHNRCWLNTETGFIWSFLGPVCTVIVINSLLLTWTLWILRQRLSSVNAEVSTLKDTRLLTFKAFAQLFILGCSWVLGIFQIGPVAGVMAYLFTIINSLQGAFIFLIHCLLNGQVREEYKRWITGKTKPSSQSQTSRILLSSMPSASKTG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QH00-1", "uniprot_id": "A0A8M9QH00_DANRE", "id": "A0A8M9QH00-1", "name": "", "aln": "------------MTMTDIILHKRFLKAPSTISVIMQDSTLILAFLMVTPVMSTAANLTDPCYNYTVLSDSWRSVNNTNNGYCDNSVSWSGWYRLFINGLSAHIPDTCVAVFRCGTSYPLWIRGGHPTVQDGVVTRDVCGNTGGFCCYYGSYPIG---VKACPGDYYVYELRSPTFCNSAYCADVGSVIISSTAATPVIITPDPCYTYTVLDDPWRADSSQPSKPVTKCDTSVSWSGWYRLFINGLNAHIPDTCVEQYSCGTEIALWIHGGHPTVEDGVVTRDVCGYAGGYCCFYGSFPIRVKACPR------NYYIYELLRPYFCTSAYCAVVSNMSSISTTVTPQTSSAVINITLQEG------CSNQSSGCLKNLLEQIENITAQELPLNTVTDILTVVFNASEKISVSSSSASPAQLASYGTKVLKSSEKLISTLVKPTETSAN--------VSFTLAAVEGKVFMVGPQVTLDKIPQLDTTNSSVDIDLIGIAKNNNDRSAVAFMSYTTMENLLKADFFNTTNDTIKTMMSTVISATLPKTSNTALTKAVNFTFRHIREFEPSGSLSCVYWNISEWIVDG----CSVLNSNSSHTVCSCVHLSTFALIMQTSSSPPPSDLLELLGLVCVIVGLVFFSLALLSFALCQWSPGVNNVARINICISLLSAHLLFLLTQQFLSLIRPQQVLCVAIAGLLHFLFLSAFVWMFIEAVLLFICVKNLSQISSKKREVLSSGFLCVIGYVLAMVVVCVSIGLVPEGYG-SEHCWIKTDEGFIWSFLGPVCVILALNLILFFKIVITLNSTLKNLNAEVSQMKQTKVMVFKTLGQFVVLGCPWILGFFTNGS--EVLEIVFLIFNSQQGTFIFLIYCLLNNEIRQQYKNCFTCLCSGHSIKCNK--------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :. .. . . . . : : . . . : : : . . : . : . . . : : : : : ", "identical_positions": 0, "similar_positions": 31, "identity": "0.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-331", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AB32U487-1", "uniprot_id": "A0AB32U487_DANRE", "id": "A0AB32U487-1", "name": "carbonic anhydrase", "aln": "--------------MQYERKMLNMLNKQMLLTCVAVHLLTGFCFAKDWCYFGCENSPSHWGKHYAKCNGHNQ-SPINIDTQKTIKSQELGPFDLINFNLPHTMKMLRNNGHTVECKLKAG---VVGVQGGGLKHKYTVLQFHFHWGGRDPRQQPGSEHSLNRHRWPVEMHIVSRRTDLNDSAASRVPDGFAVMGFFIDGKENVTSQVWENFMEYLQKIPRKGDTVRITDDISLQQLLTGVDLSRYYRYSGSLTTPPCDEAVQWTVFKDPIIISTDQLLRFQTVSFGYVYRPQQSLNKRTVYASAALAADASSSAVNTGTSGHYKRRLIVPIRSGKFVIH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2R0-1", "uniprot_id": "Q9W2R0_DROME", "id": "Q9W2R0-1", "name": "", "aln": "MFLPMIDLCWLKFIRAFGLVMQLAEESRFIMMLISCTMAVAFILNLYSGRTIFQDVVNAVGNRRLEMKLAKQPSPITIPESNMIKRQLKMPLHWTYYEDLPMATVLENNGNTVIMRIYTANNFMPQLSGAELLGRYQFVEAIFKWG------SLKSEHSIGKHNFCLELQALHRCAQLNNNFEYLTLS-------YLFALSHVKNEHLKQVTDHLKWISQPGSSIELPP-FHLESLLQPFGSG-YFSYEGTYDNGDVVLPTTWLINRKISVVDSRQLSEFEALYGRNGNRNCKNGREKQPLGNRNVYFNI-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :.:::: :: : ..* : :: . *:: : : :* ***.* .: ** * *:. :: .:*.***:** :: :. : :.*. * :* .:: *:** . ****:.:*.: :*:: : * ::**:. . . :: . .:*..: ::. ::*: *.: *.::.:. : *:.** .. . *: *.*: . .. * : :. ::.: ** .*::: * :. .:: .. : : ", "identical_positions": 48, "similar_positions": 115, "identity": "14.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-335", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NW81-1", "uniprot_id": "DMAC2_HUMAN", "id": "Q9NW81-1", "name": "Distal membrane-arm assembly complex protein 2", "aln": "MAAPWASLRLVAPMWNGRIRGIHRLGAAVAPEGNQKKKRTILQFLTNYFYDVEALRDYLLQREMYKVHEKNRSYTWLEKQHGPYGAGAFFILKQGGAVKFRDKE-WIRPDKYGHFSQEFWNFCEVPVEAVDAGDCDINYEGLDNLLRLKELQSLSLQRCCHVDDWCLSRLYPLADSLQELSLAGCPRISERGLACLHHLQNLRRLDISDLPAVSNPGLTQILVEEMLPNCEVVGVDWAEGLKSGPEEQPRDTASPVPA------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D7K5-1", "uniprot_id": "DMAC2_MOUSE", "id": "Q9D7K5-1", "name": "Distal membrane-arm assembly complex protein 2", "aln": "MAAPRAVLHLGAREWNGRARRIHGMSELVTPDSSREKKRTLLQFLSDHFQDIQTLREYLLQKQISKVNRENRSFTNIQEKYGPYVAGAVFILKQGGAVKFQDKEEWIRPNNRSHFLAEIQKFQNVPVEAVDASGCAINYQGLSNLLPLKELRSLSLQRCPNLDDWCLSRLYLLAGSLQELSLAGCPRISERGLACLHHLQNLRRLDISDLPAVSHPGLTQILVEEMLPHCEVLGADWAQNLKLEPDKQPPDTSTPLSS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "R4GEM5-1", "uniprot_id": "R4GEM5_DANRE", "id": "R4GEM5-1", "name": "Distal membrane-arm assembly complex protein 2", "aln": "MAAPLVRHAMRRCLAHNCAVTVRRG---LRSGATPSVFTRLLLKLDHYFYDVESFLYLKEWWKTKVVKFQNKYFGYVQKRYGAQIGAAYYILAIKGSFRFAGQSQWFRPDSTGMFS--FMRSPHGQIEEVDLSGTLINLNGLGNLISQNKLKTLSLRGCPEVDDWFLARLHVFRDSLVELDLSDCTHVTVGGLAALQNLRKLKRLDISGLPRLQCPGLVRILLEEMLPHCQVIGVESEQGMIQPERQEPTDIDDASTQSGLRRS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** . : :. :: : . .. . :* * .:* *:::: : *: :*: : :::::*. ..* :** *:.:* .:. *:**:. . * : . . :* ** .. ** :**.**: ::*::***: * .:*** *:**: : .** **.*:.*.::: ***.*::*::*:*****.** :. ***.:**:*****:*:*:*.: :.: ::* * . . ", "identical_positions": 74, "similar_positions": 93, "identity": "28.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-338", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N4S7-1", "uniprot_id": "PAQR4_HUMAN", "id": "Q8N4S7-1", "name": "Progestin and adipoQ receptor family member 4", "aln": "MAFLAGPRLLDWASSPPHLQFNKFVLTGYRPASSGSGCLRSLFYLHNELGNIYTHGLALLGFLVLVPMTMPWGQLGKDGWLGGTHCVACLAPPAGSVLYHLFMCHQGGSAVYARLLALDMCGVCLVNTLGALPIIHCTLACRPWLRPAALVGYTVLSGVAGWRALTAPSTSARLRAFGWQAAARLLVFGARGVGLGSGAPGSLPCYLRMDALALLGGLVNVARLPERWGPGRFDYWGNSHQIMHLLSVGSILQLHAGVVPDLLWAAHHACPRD------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JJE4-1", "uniprot_id": "PAQR4_MOUSE", "id": "Q9JJE4-1", "name": "Progestin and adipoQ receptor family member 4", "aln": "MAFLTGPRLLDWASSPPHLQFNKFVLTGYRPASSGSGCLRSLFYLHNELGNIYTHGLALLGFLVLVPMTMPWSQLGKDGWLGGTHCVACLVPPAASVLYHLFMCHQGGSPVYTRLLALDMCGVCLVNTLGALPIIHCTLACRPWLRPAALMGYTALSGVAGWRALTAPSTSARLRAFGWQAGARLLVFGARGVGLGSGAPGSLPCYLRMDALALLGGLVNVARLPERWGPGRFDYWGNSHQIMHLLSVGSILQLHAGVVPDLLWAAHHACPPD------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FEU9-1", "uniprot_id": "E7FEU9_DANRE", "id": "E7FEU9-1", "name": "", "aln": "MGYFTGPKLLDFKSSPPHLQFNKYVHTGYRPISTCRECLRSLFYLHNEFGNIYTHGVPFICFLLFLPVSIPWAEVD-EWWIGIVHYLACLSPTICSVFYHLFMNHEGGAPIYDTLLCFDMFGVCLVNTLGALPIIHITLLCHPITRQVAMLAYLLLSGYGVHCALTAESNIHRLQSFIWQAGFRFVLFMFRLIGPGRGSPSSLQLYLTMDALAMFGGLVNVSRFPERFSPGRFDYWLNSHQIMHIMVVLSILYLHWGMLEDLRWLKGYHCPDEYGIYDI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:::**:***: **********:* ***** *: ***********:*******:.:: **:::*:::**.::. : *:* .* :*** *. **:***** *:**:.:* **.:** *************** ** *:* * .*::.* *** . **** *. **::* ***. *:::* * :* * *:*.** ** *****::******:*:***:.******* *******:: * *** ** *:: ** * : ** : ", "identical_positions": 156, "similar_positions": 63, "identity": "55.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-344", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZN85-1", "uniprot_id": "A0A8I5ZN85_RAT", "id": "A0A8I5ZN85-1", "name": "Jumonji domain-containing protein 1C", "aln": "MAVETRPELVGKRFLCVAAGEDARPERGQSGCG-RGWRAGVIRAVSHRDRGHPDLAVYVEFDDLEWDKREWVKVYEDFSTFLVEYHLIWAKRKDPSQTQGSKSRQIQWPALTFKPLVENSIPSSVTAVEFLIDKQVDFLTEESAFQLYQDDIDSLKPELRDNPQLHAEVKVWVKEQKVQEIFMQGPYSLNGYRVRVYRQDSATQWFTGIITHHDLFTRTMIVMNDQVLEPQNVDPSMVQMTFLDDVVHSLLKGENIGITSRRRSRASQNISTVHG---------------HYTRAQANSPRPAMNSQAAVPKQNTHQQQQQ--------------------------------------RSIRPSKRKGSDSSAPDEERMKGDKYDYGSRGENPKGKNKHMVTKRRKPEEDEKRLTMKRLRTDNASDASESSDSENSSKRITENSS-EQTPEYELKNKITSKINGEDGQPQAAEKAGEEILIDTRPHWDQMQEDKNHEEGEKLKSMDS--HLQDKITLRASEQATDADPNSNDSVLQECNMENQRTVELPSKDRVVS---RTPTPKCAMDIKNDTHSERAAQEKS-NTFGLQIPENMDSNVSDSKH--SNAKYLEAAKKDCDQSWVSDVV--KVDLTQSSTTN----TPSGNDNREMEKERNHYVSYMSSLSTVSVTEDQLHKRSPPPETIRSKLTTSVDTQKTKSSSSPEVFKPKVTHSPDSVKSRAAYGNSQAAGER----------RQASKAEHELSRGSFHAAPTRGSALETTKSPLIIDKNEHFTVYRDPALIGSEAGANHISPFLSQHPFPLHSSSHRTCLNPGSHHPALTPGPHLLAGSSSQTPLPTINTHPLTSGPHHPVHHPHLLPTVLPGVPTASLLGGHPRLESAHTGSLSHLALAHQ----QQQ-LLQHQSPHLLGQAHPSASYNQLGLYPIIWQYPNGTHAYSGLGLPSSKWVHPENAVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPPRPHKMTVHSSPPLTKTLADHHKEELERKAFMEPLRSNASTSVKGDLDLNRSQAGKDCH-LHRHFVGP------RLPPETGERLNKYKEEHRRILQESIDVAPFTTKIKGHEVERENYSRVVPSSSSPKSHAIKPDKDMDRSVSELYKMKHSVSQSLPQSNYFTTLSNSVLNEPPRSYPSKEVSSIHTEKQNSNLSAAAN-PQTLS-FISSLSKPPPLIKHQPESESLVGKVPDHLPHQSASHSVTTFRSDCRSPTHLTVCSTNALRSMPALHRAPVFHPPIHHSLERKESSYSSLSPPTLTPVMPVNAGGKAQESQKPPTLIPEPKDSQADLK-SSDQSLVEVWR-SNN-LSKEKAEWPVEKNSGKSQAAVASVIVRPPSSTKVDSVPSGPLAAKDRVCERASSGANKTDYLKP-EAGETGRILLPNVNLESAHVKSEKNFEAASQGSVPVSVMSAVNVVSATQT-DVLTSAGPTTSVSSLAGSEATYSLSNIISASTPLECPSSKS-VSQSVAQAKGCKVSTPVPVTLACSKTANAVQPGSGFSGTTDFIHLKKHKAALAAAQYK-NSNVSEAELNTVRNQTAAASLPLDSTMTCAASNKAVSVGNGPAAQPSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGTCVSEMIKPCSVNLIASTSSDIQNSVDGRVTVDKYGRDEKASRRKAKRTYESGSESAD-SDGSESKAEQRTKRQPKPTYKKKQNDLQKRKGE---IEEDLKPNGVLSRSAKEKSKLKLQNSSSAGVPRSVLKDWRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECR--LIRSKKGEESTHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPD-QYDDEAMSLWTHENYE---DDDIDVETSKYILDIIGDKFCQLVTSEKTALSWVK-KDAKIAWKRAVRGVREMCDACEATLFNVHWVCRKCGFVACLDCYKAK---------ERKSSRDKELYAWMKCVKG---QPHDHKHLMPTQIIPGSVLTDLLDAMHVLREKYGIKSHCHCANRQNLQGGNVPTMNGVSQ--VLQNALHHSNKTSACPPESQQQSTPQRAQANGSSSPGS-ASTDSRLTPPESQSPLHWLADLAEQKSREEKQ---------ENKEFTLEKEIKEDEEQDTPDSPNGSTSPPASQNSEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGASSGKGGRTMPNILDDIIASVVENKIPPNKTSKINVKSEPNEEPKESRQSATNESNKFYRDIPHTWICDQHVLWLKDYKNSNNWKLFKECWKQGQPAVVSGVHKKMNVSLWKAESISLDFGDHQADLLNCKDS-IVSNANVKEFWDGFEEVSKRQKNKGGETVVLKLKDCPSGEDFKTMMPARYEDFLRSLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSAYGVAAAKDHDIGTTNLHIEASDVVNVLVYVGIAK-GNGVLSKAGILKKFEEEELDDILRKRLKDSSEIPGALWHIYAGKDVDKIREFLQKVSKEQGLEVLPEHDPVRDQGWYVNRRLRQRLLEEYGVRACTLVQFLGDAIVLPAGTLHQVQNFHSCIQVTEDFVSPEHLVQSFHLTQELR-LLKEEINYDDKLQVKNILYHAVKEMVRALKMHEDEVEDMEDT-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q69ZK6-1", "uniprot_id": "JHD2C_MOUSE", "id": "Q69ZK6-1", "name": "Jumonji domain-containing protein 1C", "aln": "MAVETRPELVGKRFLCVAAGEDARPERGQSGCG-RGWRAGVIRAVSHRDRGHPDLAVYVEFDDLEWDKREWVRVYEDFSTFLVEYHLIWAKRKDPSQTQGSKSRQIQWPALTFKPLVENSIPSSITAVEFLIDKQLDFLTEDSAFQPYQDDIDSLKPVLRDNPQLHAEVKVWVKEQKVQEIFMQGPYSLNGYRVRVYRQDSATQWFTGIITHHDLFTRTMIVMNDQVLEPQNVDPSMVQMTFLDDVVHSLLKGENIGITSRRRSRASQNISTVHG---------------HYTRAQANSPRPAMNSQAAVPKQNTHQQQQQ--------------------------------------RSIRPNKRKGSDSSIPDEEKMKEDKYDCVSRGENPKGKNKHVVTKRRKPEEAEKRLSMKRLRTDNASDASESSDAESSSKRVTETSSSEPMPEYEPKNKVTSKVNGEEGQSQAAEEAGEETLIDTRPPWDQMQEDKNHNEGEKPKSTDS--HLQDKMTLRSSEQATVADHNSNDSVLQECNVENQRTVELLPKDRLVS---RTPTPKCVTDIKNDTHSERAAQENL-NTFGLQTPENMDPNVSDSKH--SNAKYLETAKQDCDQSWVSDVV--KVDLTQSSVTN----APSGSDKRDTEKERNHYVSYMSSLSAVSVTEDQLHKRSPPPETIKAKLTTSVDTQKAKSSSSPEVVKPKITHSPDSVKSKAAYGNSQAVGER----------RLANKIEHELSRGSFHPVPTRGSALETTKSPLIIDKNEHFTVYRDPALIGSETGANHISPFLSQHPFSLHSSSHRTCLNPGTHHPALTPGPHLLAGSTSQTPLPTINTHPLTSGPHHPVHHPHLLPTVLPGVPTASLLGGHPRLESAHASSLSHLALAHQ----QQQQLLQHQSPHLLGQAHPSASYNQLGLYPIIWQYPNGTHAYSGLGLPSSKWVHPENAVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPHKITVHSSPPLTKTLADHHKEELERKAFMEPLRSNASTSVKGDLDLNRSQAGKDCH-LHRHFVGP------RPPQETGERLNKYKEEHRRILQESIDVAPFTTKIKGHEVERENYSRVVPSSSSPKSHAIKQDKDVDRSVSEIYKMKHSVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYTEKQNNNLSATAN-PQTHS-FISSLSKPPPLIKHQPESESLVGKIPDHLPHQSASHSVTTFRSDCRSPTHLTVSSTNALRSMPALHRAPVFHPPIHHSLERKESSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDSQSNFKNSSDQSLTEMWR-SNNNLNREKAEWPVEKSSGKSQAAVASVIVRPPSSTKVDSVPSVPLASKDRVCERSSSGANKTDYLKP-EAGETGRIILPNVNLESAHVKSEKNFEAVSQGNVPVSVMSAVNVVSTTKA-DVFTSAATTTSVSSLSSAETSYSLSNTISASTPFECTSSKSVVSQAVAQAKDCTVSTAVPGTLACSKTGSAVQPGSGFSGTTDFIHLKKHKAALAAAQFK-NSSVSEAELNTVRNQTVAASLPLDSTMTCTASNKAISVGNGPAAQSSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSNDIENRADGRVAVDKYGRDEKVSRRKAKRTYESGSESGD-SDESESKSEQRTKRQPKPTYKKKQNDLQKRKGE---VEEDSKPNGVLSRSAKDKSKLKLQNSNSAGVPRSVLKDWRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECR--LIRSKKGEESTHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPD-QYDDEAMSLWTHENYE---DDEVDVETSKYILDIIGDKFCQLVTSEKTALSWVK-KDAKIAWKRAVRGVREMCDACEATLFNVHWVCRKCGFVACLDCYKAK---------ERKSSRDKELYAWMKCVKG---QPHDHKHLMLTQIIPGSVLTDLLDAMHILREKYGIKSHCHCTNRQNLQGGNVPTMNGVSQ--VLQNVLHHSNKTSVSLPESQQQNSPQKSQTNGNSSPGS-ASTDSRLTPPESQSPLHWLADLAEQKSREEKQ---------ENKEFTLEREIKEDGDQDASDSPNGSTSPPASQSNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGTSSGKGGRTMPNILDDIIASVVENKIPPNKTSKINIKSEPNEEPKESSLPATDESNKSYRDIPHSWICDQHILWLKDYKNSNNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQADLLNCKDS-IVSNANVKEFWDGFEEVSKRQKNKGGETVVLKLKDCPSGEDFKAMMPTRYEDFLRCLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSAYGVAAAKDHDIGTTNLHIEASDVVNVLVYVGIAK-GNGVLSKAGILKKFEEEELDDVLRKRLKDSSEIPGALWHIYAGKDVDKIREFLQKISKEQGLEVLPEHDPIRDQSWYVNRKLRQRLLEEYGVRACTLIQFLGDAIVLPAGTLHQVQNFHSCVQVTEDFVSPEHLVQSFHLTQELR-LLKEEINYDDKLQVKNILYHAVKEMVRALKMHEDEVEDMEDT-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15652-1", "uniprot_id": "JHD2C_HUMAN", "id": "Q15652-1", "name": "Jumonji domain-containing protein 1C", "aln": "MAVETRAELVGKRFLCVAVGDEARSERWESGRGWRSWRAGVIRAVSHRDSRNPDLAVYVEFDDLEWDKREWVKVYEDFSTFLVEYHLIWAKRNDPSQTQGSKSKQIQWPALTFKPLVERNIPSSVTAVEFLVDKQLDFLTEDSAFQPYQDDIDSLNPVLRDNPQLHEEVKVWVKEQKVQEIFMQGPYSLNGYRVRVYRQDSATQWFTGIITHHDLFTRTMIVMNDQVLEPQNVDPSMVQMTFLDDVVHSLLKGENIGITSRRRSRANQNVNAVHS---------------HYTRAQANSPRPAMNSQAAVPKQNTHQQQQQ--------------------------------------RSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSS-EQKPENELKNKNTSKINGEEGKPHNNEKAGEETLKNSQPPWDQIQEDKKHEEAEKRKSVDT--QLQEDMIIHSSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVS---RPPTPKCVIDITNDTNLEKVAQENS-STFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVV--KVDLTQSSVTN----ASSGNDHLNMEKEK--YVSYISPLSAVSVMEDKLHKRSPPPETIKSKLNTSVDTHKIKSSPSPEVVKPKITHSPDSVKSKATYVNSQATGER----------RLANKIEHELSRCSFHPIPTRSSTLETTKSPLIIDKNEHFTVYRDPALIGSETGANHISPFLSQHPFPLHSSSHRTCLNPGTHHPALTPAPHLLAGSSSQTPLPTINTHPLTSGPHHAVHHPHLLPTVLPGVPTASLLGGHPRLESAHASSLSHLALAHQ----QQQQLLQHQSPHLLGQAHPSASYNQLGLYPIIWQYPNGTHAYSGLGLPSSKWVHPENAVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPLKITAHSSPPLTKTLVDHHKEELERKAFMEPLRSVASTSAKNDLDLNRSQTGKDCH-LHRHFVDPVLNQLQRPPQETGERLNKYKEEHRRILQESIDVAPFTTKIKGLEGERENYSRVASSSSSPKSHIIKQDMDVERSVSDLYKMKHSVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQPESEGLVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPIHHSLERKEGSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDSQANFKSSSEQSLTEMWR-PNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKT-DVITSAADTTSVSSWGGSEVISSLSNTILASTSSECVSSKS-VSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYK-SSNASETEPNAIKNQTLSASLPLDSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIVDKYVKDDKVNRRKAKRTYESGSESGD-SDESESKSEQRTKRQPKPTYKKKQNDLQKRKGE---IEEDLKPNGVLSRSAKERSKLKLQSNSNTGIPRSVLKDWRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECR--LIRSKKGEEPAHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPD-QYDDEAMSLWTHENFE---DDELDIETSKYILDIIGDKFCQLVTSEKTALSWVK-KDAKIAWKRAVRGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAK---------ERKSSRDKELYAWMKCVKG---QPHDHKHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMNGVSQ--VLQNVLNHSNKISLCMPESQQQNTPPKSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQKAREEKK---------ENKELTLENQIKEEREQDNSESPNGRTSPLVSQNNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGAPSSKSGRTMPNILDDIIASVVENKIPPSKTSKINVKPELKEEPEESIISAVDENNKLYSDIPHSWICEKHILWLKDYKNSSNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQADLLNCKDS-IISNANVKEFWDGFEEVSKRQKNKSGETVVLKLKDWPSGEDFKTMMPARYEDLLKSLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSAYGVVAAKDHDIGTTNLHIEVSDVVNILVYVGIAK-GNGILSKAGILKKFEEEDLDDILRKRLKDSSEIPGALWHIYAGKDVDKIREFLQKISKEQGLEVLPEHDPIRDQSWYVNKKLRQRLLEEYGVRTCTLIQFLGDAIVLPAGALHQVQNFHSCIQVTEDFVSPEHLVESFHLTQELR-LLKEEINYDDKLQVKNILYHAVKEMVRALKIHEDEVEDMEEN-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AY68-1", "uniprot_id": "A0A8M3AY68_DANRE", "id": "A0A8M3AY68-1", "name": "Jumonji domain-containing protein 1C", "aln": "-------MVVGKRFLCVSGEEPLDP----AHIAHWSWRAGVIRAVTHRDHDNPELTVYVEFDDLEWDKREWVKVYEDFQIFLLEHQLVWAKRKEGAQLQGTKAKQIQWPALTFKPLVGKTVFGSITAIEFFSDRHLDFNADEGACQPYQDEVDSLSPVLRDYPHLHEEVKAWVKDQKVQEIFMQGPYSLNGYRVRVYRQDSATQWFTGIITHHDLFSRTMVVMNDQVLEPQNVDPFMVQMTFLDDVVHSLLKGENIGITSRRRSRSSQNSNTAHQTTGGRPSGSTGITQGHYTRAQANSPRPVMNSSGSTPKQASQAQQQQQQQQQQQQQQTQHAQQQVSQQHHHQQQQQQPQSSPGQQRGSRSTRRKGSDSSVPDDEKIKDEKSE--SGGKDSSKNKSKQTNKRRKADEEDKKGSLKRLKTE-ASDLSESSDSENSNKRSVDSSS-EHSSENELKCKSTSKVPEEEEKSQGSKSMDELSVINRLSPWDEMQDKSSKPIALEVTQLAESERLGERRSPLPPLASCTQNQASGPMEVQSCIVKS--TVNTLPKDHYGTGIPRTHTPKCVIDITEDSTTQPSSKENSEAVSALLASQKCDGYIPESRHLVLNTSHLECRRPDGEQQQNSRNIGSKIEFAHSEVIRPVTSVSESAALGERGKLQQQYTSMVIKNASVTEEIRKTHKPSPSPDLPKPKSNSSPDILKPKCNPSPDILKSKAHSIHESCKPKPNTSPEVSKHKQRHPENLPTTGRLALKPEPDIPRSSFKPVPARGAPCESTKSPLVVDKNEHFTVYRDPALLRPESDSNHT-AYLHPHLHPLHGSSHATCLTPTSHHP-----THLLPSSS----------------MSHSVHHPHLLQTVLPTIPPGSILSSHPRLD---SSGLGHLALAHHHPHPPQQYLQQQPPPSLLAQTHGGASYNQLGLYPIIWQYPNGTHSYP----PGYKWVHPENAVNSDSSLRRNTTSPWLHQPTPVTSADSMGILSHVPGRPASADPHRSIKISSHSSPPLSKTPGELHKEDQEKSVFVDPMRSLASAHLKQEPDRSRTPTNKELHRLYMESPHNKQQLPPRMPQEGPDRTSKYKEENRRILLESIEMAPFTAKIRAGEAEHEPFPRPISS--QPKSH----EKETEHSMADLYKYKHSVSQSLPQTNYFTTLSNSVVNEPPRLFQSKDLN-PYFDKAPPTSSPLSLGSYNPS-HTKSLSKPPPLIKHQPEGEGLMGKISEQLSQQAPIHSLGTSVVTVSDRCSPAISPSNQPKGMPALRRAPVFTPPTQQALDRKEGGYGRLSPPTLTPIQPVSQAGKVSEQQKPPTLLPELRDE----KSGAELGSADSWRTGGEAKSHEKVAWHSENSQGKPQAAMASVIVRPSTCIKYDGSPGPKMASKEQLGGRLFPGRTQADCLKVAENRESGRVILPNTNLEDPSDQYNKNLIRASPGVIPSSVAVVANSVCSTKTNEAIAAASGTFSTQSHNGPDMSFSIS-ATSVSKRLESSPINS-RPPSIVESQKGGSRTTSPSGLPQACSAGTPQAYS-----RNFVHLKKAKAALAAAQSRGSSSASESESGSVRSSQDSPTIAQENSTPSNPPSKASPLPNGQAAQVCQSNYH-KLKKAWLTRHSEEDKNTNKPEKGGNAISELIKPCSVNLIAPASGDVDMGKDSKGQEDKLSQEDRKTRRTPKRPYESCSESGDDSDSSESKLEQRTKRQPKPTYKKKQNDMQKRKGDNEKEEDEVKPNGIF-RSAKEKTKLKLASTN--GIPRSVLKDWRKVKKLKQTGESFLQDDSCTEIGPNLQKCRECR--SIRTKKGEEPTHSPVFCRFYHFRRLSYSKNGVIRIDGFSSPD-QYDEEAQSIWASDAYE---ENNLDLETSKYILSYIGDKFCQLVMTENTATTWIK-KDAKIAWKRAVRGVRESCDACEATLFNIHWVCQKCGFVVCLDCYKAK---------ERKSSKDKELYAWLKCVKG---QPHDHKHLMPTQIIPGTVLTDLVSAMHMLREKYSIKSHCSCAGKQNTLFNKLPSTNGVSQVCVLQNVLNHSNKISLCKPEGGQQNS-LKMEANGGSSPASDTSTDSKFTPPESQSPLHFLADLAEQKSREEKKGGYRTIKLSENKESGVGKMKEEKDQSDALESLHSKAS-----SLEQGSTLRDLLTTTAGKLRLGSTDAGIAFAPVYSNASQIVKSGRSMPNILDDIIASVVENKIPAGRGTKLNLKHEPLEEPKVERKKAVEEPPKLYADIPHCWLYERKLLWLKDHRNSGNWKLFRECWRQGQPVLVSGVHRRLNASLWKAESFNQEFADHQGDLLNCKDG-VMSNSGVKEFWDGFEDLTKRPKAKDGETVVYRLKDWPSGEEFMALMPSRYDDLMKNLPMPEYSDPEGNLNLASHLPTFFVRPDLGPRLCCAYGVAASQEQDFGTANLHMEVSDVISVLVYVGVAK-GNGVLSKTGVLKRLEEEDLDDNVKKRLKDSSETPGALWHIYTSKDGEKIKEFLHKVAKEQGVEIAADHDPIRDSSYYLSRKLRQRLLDEHGIQGWTVVQFLGDSVLIPAGALHQVQNLHSCIQVINDFVSPEHVGHSFHLTQELR-SSKEEMNYEDKLQVKNIFYHCVKDAVGTLKRSCAEEEEESNS-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHC5-1", "uniprot_id": "KDM3_DROME", "id": "Q9VHC5-1", "name": "Lysine-specific demethylase 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQKELAALVATRTSRKRTISSTSFSISTRTDPKSIIEIHIFNDSLPIKRACCEVEN------------------------PTLKAEQR-----------VQQEEESLGQVPPLTEEEQQRHDEFRNSGSIFLQDLPCFKLQQAQPIAGSSPIP------------KCRECRRRNLATTEGEPSSVSDVYCRFYEFRRLQFNENGELCVVGFPNPYSEPSPEDIAIWQPDKNTPPTSGYMDIQVCRYILLHAGDQFCYIWHQEAEALSLHQNTDGTIAWKKAVKGTREICDVCDTTLFNYHWTCRKCGFGVCLDCVKDRKEGLRLRRAENAAQKGCDEYHWLLCSDPSGPQEHVLTELMLTQIIAGDALNVLGRLLHEVRTLWQVPQVCGCLLSKQAIEDAQSKE-------VIQDMIKES----------------------------------------QLKQHTSYSSLASEQKVHQQQR-----------------------------------------------------LDQLHATKLEFARELGVDYVPGRVWTKETLG---------KDPITTAFDNLKHINFLRKGLAGLRRFLPP---RTMTFAYSTQLAPGVPHEFLCDGRLLRLTDAMHPDNRVLFQEVWKCGQPVMISEVARSLNLDLWHPQAFCRDFGDKPNDLINCLNGNLVPNQPMRHFWEGFQCMTKRLPDAYGKPMLLKLKDWPPGDDFAEILPTRFADLMKGLPMPEYTLRTGNLNIASCLPKMFVPPDLGPKMYNAYGSALHPDK--GTTNLHLDISDAVNIMVYVGIPQDGDTRPQMAATQKAIEIGGCDYITRARCQSPDVLPGALWHIFPARDADKIRDLLNRVTLEKGFRLEPDHDPIHDQNWYLDDKLRARLFKEYGVEGHPIVQCLGDAVFIPAGAPHQVQNLHNCIKVAEDFVSPENITHCYHLTHEFRRLSHSHTNHEDKLQIKNIIYHAIKDCCTILTRAVDERLNAELTKLNAD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . :.. . *:.:* .:. * : : :: : . *. ** * :*. ::: :. * . :::. : : . .: . * :: : :*.* : ****** : :.:** .: * *:**** ****.:.:** : : **..* : . * ::* : .. :*::..:*** **:** : * * : : .*..****:**:*.** **.*::**** **.*:**** .**** * : *. :.:. : * *: * . * * ..** ****.* .*. * :* :* : : . * * :: . .. *:*: ::.* : :. : : :*** ::::: * .. : : *: :.* .* *::..:* . * . * : : .:** :: : ::* *.* :..* **:* *: ***.::* * : :* .**:.::: :*.*: **:** :. ::.* ::.**:**: ::** *:.:: :*** *.*::* ::*:*: *::: **:*** *::*:** ** :** *****:: *** . :: **:***:: **.:.::****:.: *: . :. * :* * : * :... *******:..:* :**:::*:::: *:*..: .:***::*..:*:. :** **:.*:*:. .::* ***::.:***: *****:*.*::* :******:: ..:***:*:* :.. *::****:***:**.:*: *. * : . . ", "identical_positions": 250, "similar_positions": 296, "identity": "9.37%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-348", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LTR3-1", "uniprot_id": "F1LTR3_RAT", "id": "F1LTR3-1", "name": "Putative ATP-dependent RNA helicase TDRD12", "aln": "MLEVLVLKIEDPGCFWV-IIKGCSHFLEQEVDYQKLNSAMNDFYNSMCQDIE---IKPLMLEEGQVCVVYCQELKCWCRAVIKSIISSADHYLAECFLVDFAKYIPVKSKNIRVAVESFMQLPYRAKKFRLYCTKPVT-----------LHIDFCEDNAEIVPATKWDSAAIQYFQNILRATTQVEAKL--------CAVEEDTFEVYLYATIKNEKVCVNDDLVAKN---------FAYYVSPMGNKN----------LNTLEKPRLSLNSVPCSSKLSPSLTLWPMLLQGKDCQRMENSQSLDFLAQSLQHTWCKDVVGDLG--PRAAVLDKAVNY-KDSLTDSPTIMFEKKQQSLPLKHMDKCIESSMYWPTKRGITIYADPDIPAASVFSQKPSE--KPLRLTEKKDCD----EKNGCVKLLQFLNPDPLRADEISDLHQLQKVKLGTLQPG--------------VVLRNRIEPCLTLDKSPLSADLKK------------------------ALQRNKFPGPSHTASYSWPPIARGCDVVVISHCGNDPLLYLPPLLTILQMGGCYKSLP-----SRNGPLAVIVCPGWKKAQFIFELLGDYSMSSRPLH-PVLLTIGLHKDEA--KNMKLPRGCDVIVTTPHSLLRLLTYRSLLF--LRLCHLVLDEVHVLFFEANEQMFAILDNFKKNVEVEERESAPHQIVAVGVHWN-RHIEHLVREFMKDPHVVITALEEAALYGSVQQVVHLCLECEKTSTLLQVLDF-VPSQAQKTLIFTCSVAETEIVCKVVESNSIFCLKMHKEMAFNLKSILEQWKKKLSSGSHIVLTLTDDCIPLLAITDATCVVHFSFPSSPKVFGGRLYCMSDHFQSLTEQGSPAEQGGKKTKSVLLLTERNASHAVGVLRYLERADAKIPSELYEFTAGVLEAKEDKKARRPLCPYLKAFGFCKDKRICPDRHHINPEMDIPRKLSNETLPVFGHIRIIPFYISNATNYFGRIIDKHVDLYETLNAEMNEYFKDPSNKTAAEKVENLGLYGLEEKTLFQRVQVLEASQKEDTWGLGSVLVKFIDEG-RTKLITRDQLLLLPEKFHTLPPQAVEFIVCRVKPADSEIEWNPKVTRYIHH---KIIGKMHEAKVVFALGNTLWIDPMVHVTKLSNLKTSVIDYNVRAEILSMGMGIDNSEHVEQLKKLHKEAK---------------------------------------------LPAFVDLPSQTSIPTTVEG-------------------TMCLQGTQRGDRGTERGAGSQVDPDNQKPGVLSEDIGHETISKATQPHVRSFHPQIKWFQKDDH------------------------IILKIKIRNVKDYKCKFFTDRVIFSAWVGDKFYLADMELQGDIRKDDCKCIIKDDEPLITLAKEKRAC---------------------WCGLL--KQRNPNVAFDFDHWEECEEDSPFSKVVSSKTLSCKAAALAESSSSSSDMTDGSESE-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWU0-1", "uniprot_id": "TDR12_MOUSE", "id": "Q9CWU0-1", "name": "Putative ATP-dependent RNA helicase TDRD12", "aln": "MFEVLVLKIEDPGCFWV-IIKGCSHFLEQEVDYQKLNTAMNDFYNSMCQDVE---MKPLMLEEGQVCVVYCQELKCWCRALIKSIISSADHYLAECFLVDFAKYIPVKSKNIRVAVESFMQLPYRAKKFRLYGTKPVT-----------LHIDFCEDNAEIVPATKWDSAAIQYFQNLLRATTQVEAKL--------CAVEEDTFEVYLYATIKNEKVCVNDDLVAKN---------FAYYVSPMGNKN----------LNPLEKPRQSLNSVTCSSKLSPSLTLWPMLLQGKDYHRMEN---------------------------------KALNY-KDSLTDSPKMMLEKQQQSLPLKHTEKCTESSVYWPTKRGITIYADPDVPSVSGSSQRPNE--KPLRLTEKKDCD----EKNGCVKLLQFLNPDPLRADGTSDLHQLQKVKLGTLQPG--------------VVLRNRIEPCLTLEKSPLSADLKKMALTCLNSDTEDMKVAMEEMIPPEALQRNKFPGPSHTASYSWPPIARGCDMVVISHCGNDPLLYLPPLLTILQMGGCYKSLP-----SRNGPLAVIVCPGWKKAQFIFELLGDYSMSSRPLH-PVLLTIGLHKDEA--KNMKLPRGCDVIVTTPHSLLRLLTYRSLLF--LRLCHLVLDEVHMLFFEANEQMFAILDNFKKNVEVEERESAPHQIVAVGVHWN-KHIDHLVREFMKDPCVVITALEEAALYGSVQQVVHLCLECEKTSTLLQVLDF-VPSQAQKTLIFTCSVAETETVCK--------------------------------------------------------------------------------------GSPAEQGDKKTKSVLLLTERNASHAVGILRYLERADAKIPSELYEFTAGVLEAKEDKKARRPLCPYLKAFGFCKDKRICPDRHHINPEMDIPRKLSNKTLPVFGHIRVIPFYISNATNYFGRIIDKHVDLYETLNAEMNEYFKESSNKTSAEKVENLGLYGLEEKTLFQRVQVLEVSQKEDTWGLGSILVKLIDEG-RTKLITRDQLLLLPEKFHTLPPQAVEFIVCRVKPADSEIEWNPKVTRYIHH---KIVGKMHDAKVVLALGNTLWIDPMVHVTKLSNLKTSIIDYNVRAEILSMGMGIDNSEHLEQLKKLYKEAK---------------------------------------------LPAFEDLPCQTSIPTTVED-------------------TVCLQGTQQGDGGTERGAGSQEDSDNQKPGVLSEDIGSETISSAPQPHGRSFHPQIKWFQKDDV------------------------VILKIKIRNVKDYKCKFFTDRVIFSAWVGDKFYLADLELQGDIRKDDCKCIIKDDEPLITLAKEKQEC---------------------WCGLL--KQRNPNVAFDFDHWEECEEDSPFSKVVNSKNLSCKVAALAESSGSSSDTTDGSESE-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q587J7-1", "uniprot_id": "TDR12_HUMAN", "id": "Q587J7-1", "name": "Putative ATP-dependent RNA helicase TDRD12", "aln": "MLQLLVLKIEDPGCFWV-IIKGCSPFLDHDVDYQKLNSAMNDFYNSTCQDIE---IKPLTLEEGQVCVVYCEELKCWCRAIVKSITSSADQYLAECFLVDFAKNIPVKSKNIRVVVESFMQLPYRAKKFSLYCTKPVT-----------LHIDFCRDSTDIVPAKKWDNAAIQYFQNLLKATTQVEARL--------CAVEEDTFEVYLYVTIKDEKVCVNDDLVAKN---------YACYMSPTKNKN----------LDYLEKPRLNIKSAPSFNKLNPALTLWPMFLQGKDVQGMEDSHGVNFPAQSLQHTWCKGIVGDLR--PTATAQDKAVKCNMDSLRDSPKDKSEKKHHCISLKDTNKRVESSVYWPAKRGITIYADPDVPEASALSQKSNE--KPLRLTEKKEYD----EKNSCVKLLQFLNPDPLRADGISDLQQLQKLK-GLQPPV--------------VVLRNKIKPCLTIDSSPLSADLKK------------------------ALQRNKFPGPSHTESYSWPPIARGCDVVVISHCESNPLLYLLPVLTVLQTGACYKSLP-----SRNGPLAVIVCPGWKKAQFIFELLGEYSMSSRPLH-PVLLTIGLHKEEA--KNTKLPRGCDVIVTTPYSLLRLLACQSLLF--LRLCHLILDEVEVLFLEANEQMFAILDNFKKNIEVEERESAPHQIVAVGVHWN-KHIEHLIKEFMNDPYIVITAMEEAALYGNVQQVVHLCLECEKTSSLLQALDF-IPSQAQKTLIFTCSVAETEIVCKVVESSSIFCLKMHKEMIFNLQNVLEQWKKKLSSGSQIILALTDDCVPLLAITDATCVIHFSFPASPKVFGGRLYCMSDHFHAE--QGSPAEQGDKKAKSVLLLTEKDASHAVGVLRYLERADAKVPAELYEFTAGVLEAKEDKKAGRPLCPYLKAFGFCKDKRICPDRHRINPETDLPRKLSSQALPSFGYIKIIPFYILNATNYFGRIVDKHMDLYATLNAEMNEYFKD-SNKTTVEKVEKFGLYGLAEKTLFHRVQVLEVNQKEDAWALDDILVEFIDEG-RTGLVTRDQLLHLPEHFHTLPPQAVEFIVCRVKPADNEIEWNPKVTRYIHH---KIVGKLHDAKVILALGNTVWIDPMVHITNLSSLKTSVIDYNVRAEILSMGMGIDNPEHIEQLKKLREDAK---------------------------------------------IPACEESLSQT--PPRVTG-------------------TSPAQ--DQDHPSEEQGG-------------------------------------------------------------------------------------------------------------QGTPPAEDAACLQ-SPQPEDTGAEGGAES---------------------KTSSE--NQK-PGGYLVFKRWLSSNR------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TJS0-1", "uniprot_id": "A0AB32TJS0_DANRE", "id": "A0AB32TJS0-1", "name": "RNA helicase", "aln": "MLEIQIIKIEDPGCLWARVLKGPGLQVVSPEEYENLKVRMNLFYHEVDLDVQK--LKPSELKEGLVCVVFSVALKSWCRAIVESVLQGVLDTQAWCLLVDYGDRIIVREDDVRTPLEKFLLLPFRVRRFRLAAVRPMT-----------LQVPLSEDTAELVPSASWDSSATKYLLNLLQVSTLVEAVL--------CETQDDCSSIELYLTINNTKICVNHELVAKK---------FACFVSDADGSRSTDRAPVSLAWDIYSSPHQLLEMKGCCPLRAPPPDTPTRKQRTDHTHTEAEQQKAEAAEEIHTPSVGKPPVQKLRRNPGTYTIGRGWRIRAEATDLFTAQIHHSKSQYMKFTTLLQPKQIPESVEEKQSSPGQTDDNSEGSRVYNAIDSEELKEADLPQEPSLD----DQLACARLMQFLNPDPLNPDQETVDAKVARCDPGHSGVL--------------VHSAIRIEPCSNLTRAPITEQFRK------------------------FLLWRKYSGPNVAESYCWPAVARGFDTVLVSHSGDNPLSYIPPLLMILHTVSVVSSLA-----ARTGPVAVILCPGWEKVQTVLELLED-SKATHGLH-PTSVLLGVDQDEP--KKFKIQKNCQLLVTTPFSLLRLLEAQCFLF--LRLCHLVLDEADLLYSQAPDQISIILKHFQQLVCAEERVACPRQIIAVGGRWS-AGIDGLVREHMIHPTVIITVMEEAALYGRVHQRVQLCLDCDKVSVLLSSLDF-QPPKPQKTLIITNSAEETEHVYKAVVNTAVFTLKAHEDATDQFDFIIDQWKKDISQGTQVILVTTNDCLKALGIRDATCVVHYGFPSTPKLFGSRLFCMSENFRKLS-DVDHSEDWTPGAQSVLLLSEQNVRHVCGVLRYLRRTGALLPPELLQFALGIQQAKEEQKTHRPLCCSLKSFGFCRDSTVCPDRHTIN------TSLDQTQLPDSGMIMVLPLFIKTASVYCGRIVRQKEDLYEDLATQMKLHYAN--ERRCAVEVLKGALYAVQEENCYHRVRVLEVPEK-GEQLFSSVTACFIDEG-RTQEVKSHQLLQLPAQFQDLPGQAVEIILCRVQPVDGEVDWNPKVTRAVSL---KIRGKLHQARVVMSLGNTIWVDPMVRMVRVPGLKTFINEYNVHTEILASGFGVSNPQHVDLLKTVFQRDQNHNMLDQQLSEHRFESALLSSQQRMEVSED------FLTSRMKDLVSGHNAMFIQNNTAVVCNGGMKSGEDAELSARSAGSDLNGFASLIHTGPSSSESESDEAVDQLQTLNNNNNNTPQAPYNSKLFSFQLTSFHPQIKWFQRGES------------------------VTVCIKLISPVMQKCEFSCDAVVYSGYVNDRHYYAKLELFGDIIAEECSWEMKCNEPVMKLMKKDKRD---------------------WTTLL--KHKSAFVSYEFDRIEEACVT------VNGHSFLAEVGEDGCYVSSESDSDSD---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VL52-1", "uniprot_id": "SOYB_DROME", "id": "Q9VL52-1", "name": "Putative ATP-dependent RNA helicase SoYb", "aln": "-MEHQLDPDQEESILITHFVNPHQFSYVRCIDVENSAMLVRQIEQDLKDYCSSERTKQVYVEDERVIVRYQRWSP---PKLVRGVVRRRQNEEYLVWILDYGFNLCCSVWDLWPLPDHLSRSLCDFKEGGVALIAPHSGSVWSRSAIESLDKQLEDANQLTFQVVHRGKSNRNFGLLKFRSSCQTEDAANFLIKQDQGRCKETLTMAIPYEDISFEKAEINDMAIDTRPRLRRILELVVLLSENAKESTPTPSAIQQKKLDALLQSHETYLIPNSVKLLSKVQSISESSMQTALANRSKQISKELPHKANQSEDNRKKEVKYLESENLSECLSKVKLSSYQQKNTDSSTLSGPRNLASSSTNSNSNVRKSMTLFKSSGAHLTTSLSVPLTENCTNQSNNRTVVFSMDKMEQIFNDMLGKNPSERSVQKNRSQMPNSNVSTTKRCVEKMHVCRSENMGDRKPSVCLKHLVLAHSPEPVNPVTSYKELPLGNTILN------------------------AMDDLNFQTPLPTQIYAWPHLVNRGSLVLVNPSGTGRSWSYLPVICSSVLSSFENVTSNLDTRIAPGPLAILIVDSVENAKKLASHCEFLMKDFNTQN-LKVVNTHAHSMMD--VYMMLLNSCGVLVTTLAHLNNILSNELPLVNPTRLEFIIFDDYDRKRLDNAELLKEVFQKVNSIGGLS------KQLVLVAQQWH-SERFQKLLNRTTKPLILFGDFLEAALYGGLKFNVTLRSSALKARQLLDILAE-QDGSKKRTLIYCKNQMELEELSAILIEAGLQCVDISKAQN--------------QSPNRLMLVDDSQVRKQLPVRNIQLLIHFSLPESWLRFSRRFHTMADNIRNLF---TKPIGRGQDLITYILMDENNAKEWPRIMKFLQDHGLTT--------QSMPDSEQQLDNTLPYCPYKLSNGNCNRNQCNKRHHFLKTDLPKIGNPLLQPGTLIRCKFLKAYDPAHMAVMPMKYKSKDSTIWIDVPYPSYPSTLVFKMSFGVPRKVHN-PCKINDVCFVQHKELLSRVRIVDNPARPQVTVQLMDYGTELLQVKASQLLECPEQFRDLQQLAMDIRLSGLAGSGQGGMWSTDSIQWVQDRFADINEEIMQITVDFGVLDVAYVKEIALIEECPTMLTSVYKTFLRKELLRQGFAKIDSTSILELRAIHEQWKQEMEELRANKENIVCSSTDLDNRDSKITSLQNKQATCSSGKEEDLNPVETPLIIASPNSNETLEERKHVSDKVQNKIDELNDFNKSVEIEHVQDASPLDSSTALINTLIHELNTKSPTKKKNTQEFIKNIVHEDETQSIHHEISSSTNSLKQDKTIVVGPQDPPKELFLQYLNCATKSRESVYPMVKWHQTLTHIELVVEQQMLEYKLGLDGNTLEYKVNETTPPQRFILNLLGEVRIDSVKQHGYYLHIKLTKVGLLFHWPTLLNSLYVQKHAHWLIYDSERSHGPPPSFGLVLWEGYLTHKKTKSYSDSESSEFSSTPEDFIEPGVEYCEMDSNLYED", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VNP5-1", "uniprot_id": "BOYB_DROME", "id": "Q9VNP5-1", "name": "Putative ATP-dependent RNA helicase BoYb", "aln": "-----MIKISDEKTWQS----SRDSVYEVGDSYSGQNANRPLVATNCSEYAVAHANCQLRPVRRFAEVSLLPDILETMRNLGLNRLLRLQSYTWPHLAGGSGHGAMIVGSPASGRTFAYIPPVCHAVSRALMDFTGQC----------------EDVEHDISQPDRYGPIALILVPDLRRVHQVS-----------------AMCLALLRKAHKNDSVTLALNVSSTKS--------SQFFLKLLNGVG-----------CLVATPAQLVWFWQEAPGLMRFPCLQFLVYDDVDLMSREQ------------------------------------LQDVQQVLQEILPLSHSPQVVMVSKSYCHTLMSKLRAVNDKPALVFGDILEAALYGGTRIRIS-----IMRSEAKAN-------AVVQMLQQCSPEEFRTVIFCSDDGDMQCLVAALEVQ-----------------HYSCLPYYQTADLEVRQQVHS------------------------WQARSNGVILLCTDNCPELDIRDAHTIIHHSMSHSWSKFKLRHLKISDNLCNMVKPTAS----IVKKPLYSLVLLDDNNHRQLPRLVDFLQLHQKVDH-RLVEVAKRIRQELGKARNDQHQLCDQILVLGKCYDPVCESRHRLS-HIDRRPDYLPASGDVKVQLVKVYSPTHFCVRLLEHLPPKGTWRMMEYSAVQEFR-MQLTQIKEPRRYWPPVAGAICMYHTTFTKERVRVLKVAAIKNTNIVQSDLTVKLQALDVDTRIFSTNCGKLFECPEALQQEAPLACDLR-----------------------------------------------------------------------------LPGWVPYFGERSWTEENIRNVNLILTQLPKD-------------HFLQAKILFVAAGTLFVQDLVAIMYADQFKAHVRHLSLARRLVEATLVKRSENAAEMIREFFAEVIIEDDIDENVQDSKEKANSKPHEKMKGKMTDQPAKLQSQPPLSGRCLRLAN-MAHESVKENQLHQELQERRYETPEIPHQSNESDIPQSNEDRFSQLYECIMNCASLQLEDESKPAKHPDHVLSESVEFHKIMTN-EDATPDHTQEKTALLLLPNNVARPSVTYYQTMTTLEFQVFLPEDDHDYKALLLGAQ-----LFFRAISKSSD-----------------------------------------------LILQFIMTLRFPYSSMS------------------HNIRGRTVYIS--------------------------------------------------------------------------------------------------------------VKKLLALIDPLAFREYRFLKPNHDLFDKVDKQLQET---------------------QNRLVRFLEDMNYVKRNFEGQEK-----------RETSEDEEVNVEGIERPDCHKIWDL---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W4W2-1", "uniprot_id": "Q9W4W2_DROME", "id": "Q9W4W2-1", "name": "RNA helicase", "aln": "---MEPIGDLQVPSFKVVSGGTTFTYASPKSGAASLDFLAHTLRKREANTEKTILICQQNFEAERLKFELAERDVNTILLPPHGAMVGQVLLLWSKGYINQALILCDGMLEHLGVVEANLVIHTTLPELNKFEERLKW-------------LSISARNAEMLVITPCDEENEKEGKGETEPEIVQQRMP---------LKVDALNSMQLYEIKENTPPTSSEDYKAEAD---------VLLSAATPATIP----------NDNKEQEINLSVEDATVKLLASFELGSTDSAAVDESSPAAAKFN-------------------------------APVYSPFVTENPTKSLDAEFQELVKSFKVQNVFKNMNLPPPPSVSIEEPVSSASASDYRHQIDT----TSLDSIRTVK----------------DSPASLAVVPFSAGGITYNNYGVLGWS-----------------RHAVVPCYGLTEAPDISTIIR---------------------RAMQQMGVARSRARAVQRFAWPHVSLGKSVLVVGNLQIGKTWSYLPTVCQRSHEDLQRRPD-----VGRGPTCIFVCPNQGQGKQIERWMSTLLCLLGSASGFEDVVTHWDKTQLVDIVRRLKKPVGILLTSVDLLLQLLNHNPVGS-IFDAQAVKCIALDNLNDMVRVLPNDTMKLLQRLPEMFQLTQNKCQLLVSGRIWHTDLMVQHILPLMPDVLVLFDDALEASVYGGVQLDVRVVADEPEKIEHLKALIAERRNFANEPAVMVCSNSTEVLLLRR-----------------------------------------------------------------------------------------SLQAIGVNAHICVSEACYSNVAEWLRQSPSG------------LLLVTDDVVPRLKCGKIPLLIHYSFASMWARFKNRFSLFYANLKSPTTRPVGQSVVFAKPTDLENIWKLCDFYMKHKLPRPGHLLGILSQRRLEEQPTSRSLCHQMAAFGDCLRHKCMYRHVMWRDEVLPPDHYPKNGLIRFLVLVCYSPAALAVRLSDQFPTAIRFLNFPMSDLGERVQRHYELEANRHMHPNPVPGEMA-------VVKNINRYERVHIVSVESNVMVLVQLLDTSTECFSYKTSQLYSCDKIFKDSPREAMDLRILGLQPE-----------------------------------------------SLDRIWPDDARNLVRKD----------------------------------------------------------------------------------------------------------------------------------------------FFRRTHNKRNRQFHAVVQSAIHRTIFVRNIYDD-----------------------------EGNDLLSFVINRFRS----------HQDECCQLKLDAMVMSSKDCPYM------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . . . . . . : . . . * . . : : . * :: . : : : . ::. : . .. : : : : : * : . * . : . * . : . . :. . . . : : . : : : : :: : . . : ", "identical_positions": 5, "similar_positions": 65, "identity": "0.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-350", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "C9JE40-1", "uniprot_id": "PATL2_HUMAN", "id": "C9JE40-1", "name": "Protein PAT1 homolog 2", "aln": "MNCLEG------PGKTCGPLAS----------EEELVSACQLEKEEENEGEEEEEEEDEEDLDPDL--------------------------------------------------------------------------DPDLEEEEND-------------------------------------------LGDPAVLGAVHNT---------------QRALLSSPGVKAPGMLGMSLASLHFLWQTL-----DYLSPIPFWPTFPSTSSPAQHFGPRLP--------------------SPDPTLFCSLLTSWPPRF---SHLTQLHPRHQRILQQQQ-----HSQTP-SPPAKKPWSQQP---DPYANLMTRKEKDWVIKVQMVQLQSAKPRLDDYYYQEYYQKLEKKQADEELLGRRNRVESLKLVTPYIPKAEAYESVVRIEGSLGQVAVSTCFSPRRAIDAVPHGTQEQDIEAASSQRLRVLYRIEKMFLQLLEIEEGWKYRPPPPCFSEQQ--SNQVEKLFQTLKTQEQNNLEEAADGFLQVLSVRKGKALVARLLPFLPQDQAVTILLAITHHLPLLVRRDVADQALQMLFKPLGKCISHLTLHELLQGLQGLTLLPPGSSERPVTVVLQNQFGISLLYALLSHGEQLVSLHSSLEEPNSDHTAWTDMVVLIAWEIAQMPTASLAEPLAFPSNLLPLFCHHVDKQLVQQLEARMEFAWIY-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2ARM1-1", "uniprot_id": "PATL2_MOUSE", "id": "A2ARM1-1", "name": "Protein PAT1 homolog 2", "aln": "MKCLEGLHLQQRPSKFSVSLAP----------EEGLVCAFQLEEEKENE---------DECVCSDQ--------------------------------------------------------------------------APEVKEEGCG-------------------------------------------LGDPAIVSAFQNTQV-----------PQQRGLHSSHRVKVSGALGMSSASLHFMWQS----------------VFPRASSPAHHFGPQQP--------------------SPDPFLFYSPLTPWPPKLSLPSHLTQLHPQHQQILQQQQRWRRRRSPTARSVPAQKPWSREPAASDAYANLMTRKEKDWVIRVQMVQLQSENPRLDDYYYQKYYQKLEKRQADKELLGQKTRAESLKLVTPYIQKPEVYESVVRIEGSLGQVAVSTCFSPRRAIDAVSHGTQEQDTGAASSQRLRVLSQIEKMFLQLLKIEEGQNDGLPQLYHTREQ--SSQVEKLFQALKTQEQNNLEEAADNLLQVLSVRKGKVLVARLLPFLPPDQAVSLLLYITYHLPLLIQRDMADQGLHMLFKPLGKYISHLTFHQLLHAMQGLMLLSPGSSERPVSVVLQNQFGISLLYALLSHGEQLVSLDPSLR-SSSDCATWTDLVILIAWEIAQLPAASLAEPLAFPRNLLPCSAITWTSN--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FAC4-1", "uniprot_id": "E7FAC4_DANRE", "id": "E7FAC4-1", "name": "", "aln": "MGDSEDPEKNREPIPDAVWPENGDQWSDKGEDDECGLLQEMAEEDEEIDLYNEETFGLDEAVNGDTPDIDPTDLLLLSSDSSPTPQSSHPPPPPPPPPLPPKSPFTYSTHCPPRPEPHSWPHTPTGRSQRGRGGRGQLFDDPAVVKTVKGRPSLKSIDSAIVDCSLSTYWEDLNSNSWMVAPLKSSRSPAQTILQDQAIVGVIDRSAHGRVPPVSPNFLSPMRPFSTSRGRRGQPFVGSFNQRCHYQAQKTPMAPCPVFRPQRLFSPQQQYNQPGGFMSPSRPPLSTSMPRTPKLMHLRFGTDSPRPAPFYSPSASIMQGLRAPGPVVQFHPQHKRLLSQRQ-----------PRPHKKPLSWDP-----YSQIMSDKEKEWIIRLQMIQLQSENPHLDDYYYQEYYQRMETKLAEEEYVGDRTKKEPPKLTTPYVSKNVSYIPVVHIEGSLGQVAVSTCFSPRRAIDAVHASTHDEHKDTRQ-QRLEVLSTIEKLYLILLEVEEAEKVKTTVSDKEEESRLMQNMKRKVEQLYNELRCTNLDSGEEFLSCLLVSKGKRLVARLLPFLSHDSALHILSTVTKHLPVLMSRDT-DEALPILYPSLRAVINGLVFSQLIRILKEFTALLPDSQDTRLTLACQNKFGLSLLYALLSQGERLLSSDLPMEPSIGDFETWTDTVFHVARQLSQT---SLVEPLLLPSNLLTLFCRYLDKRTVHQLKNNMESATGYLAVAS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *. * . :* : *:::* : :* : * * : : . * * *::.....: * : :* : :* *: *. ..*. .:.* * ** * * * :. : . :.*:**:*:::*.*:* . * :** * :* *:::*: ***:*:*::**:**** :*:*******:***::*.: *::* :* :.: *. **.***: * * .**:*********************** .*:::. : . ***.** ***::* **::**. : . .:. .:::: .: * .: : . ::.: :*. * * *** *********. *.*: :* :* ***:*: ** *:.* :*: .* *. *.: :*:: :: : * *.*.: :::. **:**:********:**:*:* . .:. . .* :*** *. :* :::* **.*** :* ***. . .. ", "identical_positions": 180, "similar_positions": 162, "identity": "24.49%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-354", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJI5-1", "uniprot_id": "BRSK1_MOUSE", "id": "Q5RJI5-1", "name": "Serine/threonine-protein kinase BRSK1", "aln": "-----------------------------------------------MSSGSKEGGGGSPAYHLPHPHPHPPQHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAVKIVNRE------------------------------------KLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDN--LRQLLEKVKRGVFHMP--HFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWY------------------LGGKHEPDPCLEPAPGRRVAMRSLPSNGELDPDVLESMASLGCFRDRERLHRELRSEEENQEKMIYYLLLDRKERYPSCEDQDLPPR------NDVDPPRKRVDSP------------------MLSRHGKRRPERKSMEVLSITDAGSG--GSPVPTRRALEMAQHSQRSRSVSGASTGLSSS-PLSSPRSPVFSFS-PEPGAGDEARGGGSPTS-------KTQTLPSR-----GPRGGGAGEQPPPPSARSTPLPG----PPGSPR--------------------------SSGGTPLHSPL--------------HTPRASP------------------TGTPGTTPPPSPGGGVGGAA-----WRSRLNSIRNSFLGSPRFHRRKMQVPTAEEMSSLTPESSPELAKRSWFGNFISLDKEEQIFLVLKD--KPLSSIKADIVHAFLSIPSLSHSVLSQTSFRAEYKASG-GPSVFQKPVRFQVDISSSEGPEPSPR-------------------------------------------------------RDGSSGGGIYSVTFTLISGPSRRFKRVVETIQAQLLST-----HDQPSVQ----ALADE------------------------------KNGAQTRPAGTPPR--SLQPPPGRSDPDLSSS-------------------------------------PRRGPPKDK-KLLATNGTPLP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2DD29-1", "uniprot_id": "BRSK1_RAT", "id": "B2DD29-1", "name": "Serine/threonine-protein kinase BRSK1", "aln": "-----------------------------------------------MSSGSKEGGGGSPAYHLPHPHPHPPQHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAVKIVNRE------------------------------------KLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDN--LRQLLEKVKRGVFHMP--HFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWY------------------LGGKHEPDPCLEPAPGRRVAMRSLPSNGELDPDVLESMASLGCFRDRERLHRELRSEEENQEKMIYYLLLDRKERYPSCEDQDLPPR------NDVDPPRKRVDSP------------------MLSRHGKRRPERKSMEVLSITDAGSG--GSPVPTRRALEMAQHSQRSRSVSGASTGLSSS-PLSSPRSPVFSFS-PEPGVGDEARGGGSPTS-------KTQTLPSR-----GPRGGGAGEQPPPPSARSTPLPG----PPGSPR--------------------------SSGGTPLHSPL--------------HTPRASP------------------TGTPGTTPPPSPGGGVGGAA-----WRSRLNSIRNSFLGSPRFHRRKMQVPTAEEMSSLTPESSPELAKRSWFGNFISLDKEEQIFLVLKD--KPLSSIKADIVHAFLSIPSLSHSVLSQTSFRAEYKASG-GPSVFQKPVRFQVDISSSEGPEPSPR-------------------------------------------------------RDGSSGGGIYSVTFTLISGPSRRFKRVVETIQAQLLST-----HDQPSVQ----ALADE------------------------------KNGAQTRPAGTPPR--SLQPPPGRPDPDLSSS-------------------------------------PRRGPSKDK-KLLATNGTPLP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TDC3-1", "uniprot_id": "BRSK1_HUMAN", "id": "Q8TDC3-1", "name": "Serine/threonine-protein kinase BRSK1", "aln": "-----------------------------------------------MSSGAKEGGGGSPAYHLPHPHPHPPQHAQYVGPYRLEKTLGKGQTGLVKLGVHCITGQKVAIKIVNRE------------------------------------KLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGALPFDDDN--LRQLLEKVKRGVFHMP--HFIPPDCQSLLRGMIEVEPEKRLSLEQIQKHPWY------------------LGGKHEPDPCLEPAPGRRVAMRSLPSNGELDPDVLESMASLGCFRDRERLHRELRSEEENQEKMIYYLLLDRKERYPSCEDQDLPPR------NDVDPPRKRVDSP------------------MLSRHGKRRPERKSMEVLSITDAGGG--GSPVPTRRALEMAQHSQRSRSVSGASTGLSSS-PLSSPRSPVFSFS-PEPGAGDEARGGGSPTS-------KTQTLPSR-----GPRGGGAGEQPPPPSARSTPLPG----PPGSPR--------------------------SSGGTPLHSPL--------------HTPRASP------------------TGTPGTTPPPSPGGGVGGAA-----WRSRLNSIRNSFLGSPRFHRRKMQVPTAEEMSSLTPESSPELAKRSWFGNFISLDKEEQIFLVLKD--KPLSSIKADIVHAFLSIPSLSHSVLSQTSFRAEYKASG-GPSVFQKPVRFQVDISSSEGPEPSPR-------------------------------------------------------RDGSGGGGIYSVTFTLISGPSRRFKRVVETIQAQLLST-----HDQPSVQ----ALADE------------------------------KNGAQTRPAGAPPR--SLQPPPGRPDPELSSS-------------------------------------PRRGPPKDK-KLLATNGTPLP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GWU6-1", "uniprot_id": "A0AC58GWU6_DANRE", "id": "A0AC58GWU6-1", "name": "", "aln": "-----------------------------------------------MS-----------------KELSVTQAAQYVGPYRLEKTLGKGQTGLVKLGIHCITSQKVAIKIVNRE------------------------------------KLSESVLMKVEREIAILKLIEHPHVLKLHDVYENNKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDERNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRRADVWSCGVILFALLVGALPFDHDN--LRQLLEKVKSGVFHMP--HFIPPDCQALLRGMIEVNPEKRLTLEAIQKHAWY------------------QAGRNEP--CPEQPPPRRVSMGRIMSLTELDPDVLDSMYSLGCFRDRVKLAQDLQCEEDNQEKMIYYLLLDRKERYPSYEDEDLPPR------NDVDPPRKRVDSP------------------MLTRHGRCRPERKSLEVLSVTEQG-----SPTPPRRALDTSTHSQRSRSVSGASTGLSSS-PLSSPRSPVFTFSEPEVVAATKATSGSTNSRPNRSHEPKTQTLPSKNAPE-RPQLQSMKSLPLPSSSSRSPSPS----PLLSPIPRFLFFPSPSAVLKSVTKSLYPMSQVTPQGSPLPTPLGTPV-------HHPHPPTATPPSSSSSSSSSRAEGGGVGVGSLSLTPPSSPGGGGGMAASSSAHWRTRLNSLKNNLLGSPRFHRRKLQVPTSEDMSSLTPESSPELAKRSWFGNFISLEKEEQIFVVIRD--KPLSSIKADIVHAFLSIPSLSHSVISQTSFRAEYKTSG-GPSVFQKPVKFQVDISFSEGERERERERE--------------------------------------------------RDRDGQKDFGIYSVTFSLISGPSRRFRRVVETIQAQLLSA-----HDQTMVQTFSACLCSS------------------------------PDEKNSRPPRTPTRQNSRRSEGGGDRCEWVERGE------------------------------GGVLLQRRGSGKERTRLLSSSGTQSQP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUV4-1", "uniprot_id": "Q9VUV4_DROME", "id": "Q9VUV4-1", "name": "non-specific serine/threonine protein kinase", "aln": "---------------------------------------------------------------MQKENNVTAENCQFVGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINRE------------------------------------KLSESVLMKVEREIAIMKLIDHPHVLGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNN-IKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPFDDDN--LRQLLEKVKRGVFHIP--HFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWV------------------TAG-GKGELELELPMMEVVQTHVIPTATAVDPDVLNAICSLGCFKEKEKLIQELLSSSHNTEKVIYFLLLERKRRRPALEDDDEIAQKSRSELDAVDPPRKRLDTCRINGT-------NAPSYGQISEGSPLTPRRQAFNFRSYSSTRNHQRRSPTTVTSSVRSSSYHSPTRCNSPMSSAQQQANAISRPSSPAAGTR--HSTYGDRDRSGHHSSVSRTPSHSSQKSIEGDVVVVREPRIERRDSLRQERGGGSPRDRGDCGIPPGSPGG-------------------------NSSGSTSASPS------------VHHRANSGPTIAISMFHDPDSNSVVNPNGSPMMNNSSPGMPGSPCNTPGGQLWKTRLTNIKNSFLGSPRFHRRKMQVSADEVH--LTPESSPELTKRSWFGNLITTEKDETFTILVKG--KPIATVKAHLIHAFLSMAELSHSVVSPTSFRVEYKRNGNGPVMFQRHVKFQVDISAICKQ--------------------------------------------------------------GDIADMLFALTFTLLSGNIRRFRRICEHIQSQVCSKRFPGPSSPPTVTSVTQAVSESSSCGSVSSERLSYKRQVIENDMENDSIFSYKSGNGRRASTTNNNNANPVDIPGSPIAVRSNSE--------------------------------TAEHERNRELQSERQATTMSGSAIA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34244-1", "uniprot_id": "HSL1_YEAST", "id": "P34244-1", "name": "Probable serine/threonine-protein kinase HSL1", "aln": "MTGHVSKTSHVPKGRPSSLAKKAAKRAMAKVNSNPKRASGHLERVVQSVNDATKRLSQPDSTVSVATKSSKRKSRDTVGPWKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDN--IKKLLLKVQSGKYQMP--SNLSSEARDLISKILVIDPEKRITTQEILKHPLIKKYDDLPVNKVLRKMRKDNMARGKSNSDLHLLNNVSPSIVTLHSKGEIDESILRSLQILWHGVSRELITAKLLQKPMSEEKLFYSLLLQYKQRHSISLSSSSENKKS-ATESSVNEPRIEYASKTANNTGLRSENNDVKTLHSLEIHSEDTSTVNQNNAITGVNTEINAPVLAQKSQFSINTLSQPESDKAEAEAVTLPPAIPIFNASSSRIFRNSYTSISSRSRRSLRLSNSRLSLSASTSRETVHDNEMPLPQLPKSPSRYSLSRRAIHASPSTKSIHKSLSRKNIAATVAARRTLQNSASKRSLYSLQSISKRSLNLNDLLVFDDPLPSKKPASENVNKSEPHSLESDSDFEILCDQILFGNALDRILEEEEDNEKERDTQRQRQNDTKSSADTFTISGVSTNKENEGPEYPTKIEKNQFNMSYKPSENMSGLSSFPIFEKENTLSSSYLEEQKPKRAALSDITNSFNKMNKQEGMRIEKKIQREQLQKKNDRPSPLKPIQHQELRVNSLPNDQGKPSLSLDPRRNISQPVNSKVESLLQGLKFKKEPASHWTHERGSLFMSEHVEDEKPVKASDVSIESSYVPLTTVATSSRDPSVLAESSTIQKPMLSLPSSFLNTSMTFKNLSQILADDGDDKHLSVPQNQSRSVAMSHPLRKQ-----SAKISLTPRSNLNANLSVKRNQGSPGSYLSNDLDGISDMTFAMEIPTNTFTAQAIQLMNNDTDNNKINTSPKASSFTKEKVIKSAAYISKEKEPDNSDTNYIPDYTIPNTYDEKAINIFEDAPSDEGSLNTSSSESDSRASVHRKAVSIDTMATTNVLTPATNVRVSLYWNNNSSGIPRETTEEILSKLRLSPENPSNTHMQKRFSSTRGSRDSNALGISQSLQSMFKDLEEDQDGHTSQADILESSMSYSKRRPSEESVNPKQRVTMLFDEEEEESKKVGGGKIKEEHTKLDNKISEESSQLVLPVVEKKENANNTENNYSKIPKPSTIKVTKDTAMESNTQTHTKKPILKSVQNVEVEEAPSSDKKNWFVKLFQNFSSHNNATKASKNHVTNISFDDAHMLTLNEFNKNSIDYQLKNLDHKFGRKVVEYDCKFVKGNFKFKIKITSTPNASTVITVKKRSKHSNTSSNKAFEKFNDDVERVIRNAGRS", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P25389-1", "uniprot_id": "KCC4_YEAST", "id": "P25389-1", "name": "Probable serine/threonine-protein kinase KCC4", "aln": "------------------------------------------------------------MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFN---------------------------NNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYN-IKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQT------------IKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRS----IQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTD--SSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFS-----QQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTR--KSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYD-----------------------------------------------------EDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQG----------------------------KNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDG----------------------------------AEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAP-TTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :**::* :*** *.:* *:*. : .: .*:*:: :. : .. :****.*:**:.*.:*: * :*:*.:. ***:**:.. ****: **.:* *. :** : *:**: .:.:**: .* ************. . *:*******:*: .:*:*********.**:: * *.* :*:****::*:***.* ***:.:* ::.** **: * :.:* :. :.: *: :: ::* :*:. * *. . . : :* .:* : * : .* . . **::* ** * ... : . . . : . . . . . . : : . . . : : . . . . : . . . : . . . . : .: *. :. .:. .: . : : : : . . :: . . :.. . . . . . ", "identical_positions": 117, "similar_positions": 172, "identity": "7.66%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-359", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CZ00-1", "uniprot_id": "DBND1_MOUSE", "id": "Q9CZ00-1", "name": "Dysbindin domain-containing protein 1", "aln": "MESPEGAGPGEIVKDVKVPQAALN-VSAHETGDMCRTPVAEEEEEVGIPIPAPGFLQVTERRQPLSSVSSLEVHFDLLDLTELTDMSDQELAEVFADSDDENLATESPAG------LHPLSR---ASCLRSPSWTK-TRAEQN-REKQPPSDPERQGTIVDTFLTVEEPKED--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H9R9-1", "uniprot_id": "DBND1_HUMAN", "id": "Q9H9R9-1", "name": "Dysbindin domain-containing protein 1", "aln": "MEPPEGAGTGEIVKEAEVPQAALG-VPAQGTGDNGHTPVEEEVG--GIPVPAPGLLQVTERRQPLSSVSSLEVHFDLLDLTELTDMSDQELAEVFADSDDENLNTESPAG------LHPLPR---AGYLRSPSWTR-TRAEQS-HEKQPLGDPERQATVLDTFLTVERPQED--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IZ84-1", "uniprot_id": "A0AC58IZ84_DANRE", "id": "A0AC58IZ84-1", "name": "Dysbindin domain-containing protein 1", "aln": "MEAQADSSAAEPLRDREFQKLLKSSSSASLTSEASHNASGEHVG---TPAHHGSQVLITEKRQPLSSVSSLEVHFDLLDLTELTDMSDQELGEVFADSDDEN-HTYSPAIDPTDRQQPPLPRFPHSGYVRSPSWTRGGKAEQQTRDRKHHSDSEN----TEPMLKIERSQSQQP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. .:...* ::: :. : . .* *.: :.. *. * . : :**:******************************.********** * *** **.* :. :******: :***. :::: .*.*. :.:*.:*..:.: ", "identical_positions": 69, "similar_positions": 49, "identity": "39.66%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-361", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M2BBK0-1", "uniprot_id": "A0A8M2BBK0_DANRE", "id": "A0A8M2BBK0-1", "name": "", "aln": "----------------------------------------MMANKQLALQ----VVCALICSEKQKQKKKKKRLWKRNYVERRGRPAPAAPT------------------------------------------RELEEETMTPNAGLKDLP-------------WMTSEEFEFLLSVVGPLITKQHTKMRR-AITAKDRLYVTLLFLATGETFSSLSAQYKIGASTTSQIVMETCAALYQVMKKDYLKTPSTEAEWRTIAHDFESKWQFPHCLGALGGKRIYIQPPAKTG---------TFDNYKGRCFVTATAAVDANYKFIYISVDTHVTASDAGPFAQSGLCKWMDSGLLNCPPPEPLANSELKIPYMFVGDETYPLRPDLMTPYPSKPTDRSQQILNYRLSRAQRAADNAFGILANRFRFLRNTIYLEPEKVLKILTASMCIHNFLLE-----RRSEGYAPPGLADWENEEHSLVEGTWRD-----------KGTGSLRPAEQKRECSASATAEMQQS---------LLCDYFVSPAG-----YVPWQEQHVSNEGELLLVTL-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VS98-1", "uniprot_id": "Q9VS98_DROME", "id": "Q9VS98-1", "name": "DDE Tnp4 domain-containing protein", "aln": "MDKIKLKVIGVLRERDGGNRSGSGGLGASAGAGAGSGGVTATAGHQLASAGGAGVAQPSIGVTQDNNNEGNAPGGGGAVIEPQATGGAAGPSGGVGGAARTSVLSRPQTSKISALDLAGILNTRRRLEWTKEWLRKNQTEFLSKENLLSELQSRKDECYHLNYFLAITESQFRYLVQKLEPIISQYAPQRKKKSFSAEERLAITLKYLATGEVHSCRNYCFRASKFVINEMIANICLGFYEHLKDQYVTLPKTDDQWRSAAEEMERKHNLPHCVGNLFMRSIQLQGSGTASSSGAASSASAVGDDRKRATVIFTGIVDADNNFQYARVERAASSRPNDIYNQTSAIELIRHKMHALE--EQQSAEMDRQGYYFAGDSVLPATSYLVT---TRNLPKDLAVLEA-LEQVNAHADQTMRILCNMFPILAQPLRISDKHIREVVLGCVALYNFLRKTDDSFRRTSDSIVQQRAEQQQLAYSVDSDEIDDDCIMLATEEELRERAEFTPSVGLTTCFQPLCTQRGETPEGLAKRNWLLQLDFAQQSGNGSGIGIGIGNGNMSGNGSIVGSTDSASGSSNGSLY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.:*** *. . * :::::: : :* :. ..*.*: *: : * :: : *.:* :*..:*.:*:. : *:*:: .: :: :::*::** :** :*****..*. . :: . . .::: : * .:*: :*.:*:. *.*: :**: *.::* * ::***:* * : * :* ...:. :..: : *. * *. ***: :* * *: .:: . : *:. : : : * : . : * *.**.. * . *:* :: :. :*: *.:.: **::: **.* * :* :.: :. ::: ::: ..:.::*** : **:.. *: :: :*: .. * : ..: *: * . :: :: ** *.. :* : : ::*.:*.:: * ", "identical_positions": 91, "similar_positions": 179, "identity": "15.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-362", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "J3QP53-1", "uniprot_id": "J3QP53_MOUSE", "id": "J3QP53-1", "name": "", "aln": "-MFDSSQYPYNCFNDDADDYPAGSSDEEKRLTRPAYSYIALIAMAIQQSPAGRVTLSGIYDFIMRKFPYYRANQRAWQNSIRHNLSLNSCFVKVPRTEGNDKGKGNYWTFAGGCESLLDLFENGNFRRRRRRRGPKRE----------EAP-GPLEP-TARGSPGPDSA--QAPDHEAQASPTT-----HRDIKFSIDYILSSPDPFPTLRSSCHSQEARYPALEPQQMSFQFWAA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1W2PRP0-1", "uniprot_id": "FOXL3_HUMAN", "id": "A0A1W2PRP0-1", "name": "Forkhead box protein L3", "aln": "-MFDSSQYPYNCFNYDADDYPAGSSDEDKRLTRPAYSYIALIAMAIQQSPAGRVTLSGIYDFIMRKFPYYRANQRAWQNSIRHNLSLNSCFVKVPRSEGHEKGKGNYWTFAGGCESLLDLFENGNYRRRRRRRGPKREGPRGPRAGGAQGPSGPSEPPAAQGRLAPDSAGEGAPGREPPASPAPPGKEHPRDLKFSIDYILSSPDPFPGLKPPCLAQEGRYPRLEN--VGLHFWTM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F8H3-1", "uniprot_id": "E7F8H3_DANRE", "id": "E7F8H3-1", "name": "", "aln": "MMFDSSQYPYNCFNYDGEGYPSCGTDEEKKVCRPAYSYIALIAMAIQQSPENKVTLSGIYEFIMKRFPYYRSNQRAWQNSIRHNLSLNSCFIKVPRTEGNEKGKGNYWTFATGCESMLDLFENGNFRRRRRRRNLKMG---------LKEPTEAFISMDAHQAVAVRSSDSDSFMNTSHRAAQN---KPETEIKFSIDYILSTPDPLPAFR----APNSAIPHLEPQHLNLHFWTM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ************* *.:.**: .:**:*:: ****************** .:*******:***::*****:*******************:****:**::********** ****:********:*******. * : * . . *: . *: : . . :. ::*********:***:* :: : :. * ** :.::**: ", "identical_positions": 128, "similar_positions": 47, "identity": "54.24%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-363", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HCH5-1", "uniprot_id": "SYTL2_HUMAN", "id": "Q9HCH5-1", "name": "Synaptotagmin-like protein 2", "aln": "MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHRDKIHGADIIRASMRKKRP----------------------------------QIAAEQSKDRENG---------------------------------------------------------------AKESWVNNVNKDAFLPPELAGVVEEPEEDAAPASPSSSVVNPASSVIDMSQEN-----TRKPNVS-PEKR---KNPFNSSKLP-------------EGHSSQQTKNEQSKNGRTGLFQTSKEDELSE-------------------------------------------------------------SKEKSTVADTSIQKLEK------------------------------SKQTLPG-LSNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQR--TDSLKARGAPRGILKRNS--------------------------------------------SSSSTDSETLRYN----------------------HNFEPKS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KIVSPGLTIHERISE-----------------------------------------------------------KEHSLEDNSS--------------------PNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLES--------------DRLKN----------------GMEDAGDTEEFQSD---------------------------------------PKPSQYRKPSL---FHQSTS--SPYVSK------SETHQPMTSGSFPINGLHSHS-----------------------------------------EVLTARPQSMENSP-------------------------TINEPKDKSSELTRLESVLPRSP---------------ADELSHCVEPEPSQVPGGSSRDRQQGSEEEPS--------------------------------------------------------------------------PVLKTLERSAARKMPSKSLEDISSDSSNQAKVDNQPEELVRS----------------AED----------------VSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYP--LKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99N50-1", "uniprot_id": "SYTL2_MOUSE", "id": "Q99N50-1", "name": "Synaptotagmin-like protein 2", "aln": "MIDLSFLTEEEQDAILKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHRDKIHGADIIRASMRRKKL----------------------------------PAAAEQNKDTAMR---------------------------------------------------------------AKESWVNNVNKDAVLPPEIA-VVEEPEDDTDPAGPSSSLVDPASSVIDMSQES-----TRTPAVSLPKQR---KNPFNSPKLP-------------EDHSLQQTKPEQSKTGKAGLFQISKEGELSE-------------------------------------------------------------SKEKSSIPDMPRQQLEK------------------------------PKQTVSTEPENASHTKAPIPKARKLIYKSNDLEKDDNQSFPRQR--RDSLNARGAPRGILKRNS--------------------------------------------SSSSTDSETLRLN----------------------YNLDPKS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KILSPGLTIHERISE-----------------------------------------------------------KEFSLEDDSS--------------------TSSLEPLKHVRFSAVKNELPQSPRPVLGQEVGEFTVLES--------------DQLQN----------------GTEDAGDIEEFQNH---------------------------------------PELS-HKTPLS---HYQLVS--SPSDSG------REREQLMSSGSAPRDEIPCHS-----------------------------------------DILPTGPQCVESSS-------------------------VINGQQEKSSHFTKLPSELSKSP---------------SDELTQCGEPEPSQTADHSFRDHRQGSEEEHS--------------------------------------------------------------------------PVLKTLERRAARKLPSKSLEDIPSDSSNQAKVDNLPEELVRS----------------AEDDQKADQEPDTNECIPGISTVPSLPDNQFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLRRYKKSPSSLTNLSSSSGMTSLSSASGSVMSVYSGDFGNLEVKGSVQFALDYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKTYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIERQFLKTQKLNLSVWHRDTFKRNSFLGEVELDLETWDWDSKQNKQLKWYP--LKRKTAPVALETENRGEMKLALQYVPEPSPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPVFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWVEATLPLRMLLIAKLSK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "R4GE71-1", "uniprot_id": "R4GE71_DANRE", "id": "R4GE71-1", "name": "Synaptotagmin-like protein 2", "aln": "MIDLSHLSEEEQEMIMKVLKRDAELKKAEEDRIKHLQKAIPEEDRRKYMSGEWFYEVKSQRHQDRIHGSDIIMASMKQRKPSVVEYLTKSWGGRSRSISRKDSEGIMTSPKITRTAESSEHLKERENGDTLEVQQEKLNIGMRSPSKPRHNPFNSVPIELDFEETDLHYTSRPGLRKSLDRGSDSQDNHQKASHSQVNSEVSNAVHNKPPG-QKPVPKKRTKINKPQSSVSDTASSVSTQSISSQNIFATADSSIRSPPPRGIPKHSFNEPTLKSQLRQPVVSLSNVHKNSIQEKDSEESKLALGRTEESSHKTENKEKCSTSSPIKLPKSRLPVRASSQLINMPQGLQEKPKIQPRLSLNSITRPDDSRKVEEVIKQRGESNSCLPQSPSMEVERQNISVEMHHPVENAVFAFSDNSKKPLNEITTPQLTHHMSENVENQMAPFPKLETMKTEEKIKKTTTDEHFPRALNITETFNMTNASTDYETESSPLAFNIKQKTSSQEDPKSEVMTDEHITTPTDEQGDSIAKVLEWFSRSSDSSDRLDIDSNVQDMEEDSKFEDLDFDDGVDHTVKPRSNVYLIMPRQSEGPSEVNTIFLEQADWRKEQSVDEPSQNPRKERKTSESTFYKESLIKKPSVDSALTANIVNPEVPVVNISVSRKVQNENKVEALIKKEDKSEVKLADISQQKERSDAEENQRPKIANLKSFWEKENIGPKILIGKSGAPAKNEEIIPSDLAKRSTEEIEDHWRSEPNLKVMSPGLQKIETVWKNVDIEDVGTATQVPIIINESKPLIYANQKTDKIVANSTLDKKCTTSCLKSSSPALDSGSLEGSHDDDSAGGTVSINSSDADHSAQKELETKSKTAQKTSQGPSVKQNSQQENMAERIKQLRSFWEKESRTSVAAKNRSTTTTTRLNQRFTKSEFDLRTIGTEFDDGDEDDVEDITSARGRLSPNFSGHLLRKDKTVVMDGMTTSQFKNLRDFWGGSPVKTGERSPVLDSGNHRSSSPQSPNERANVKDFVNESQNSKTSSSAKMKAFQSPSKKKIMSRQESGPKPDQSQGVSGETITHGLSHSLQPQKGSKTTMVPKSQTGQESRSQQGRRSIKGNLNGKANAMRRATSMFSVNATGEEQNQDLHFQSKKVQSPNLQQVKKAPDTSLTQSRKVQEASYTLPKTSPEISWRDRDKNSQRRTSRTSEDSDSQPLARSYIPRDYQHYLGISEDKSMYTPPPVAEQVDDFICTSFTSSPETNHSCKCPPVKTSTPVHGSPDLQTRSGSLGHHLTTQTDGNIIKGIQNRENESLIQKALKRASSRPVYHKSMEDISSIARQDQKLKQTDDYMHDNYDASSTHLQTSFSTADPEHMKKLSKSVPSFLEKESDGGESD--SESSSRGSVPKWNNRQFTNLSNYSGSTSLSSVSGSVASVYTSDYNSVDVQGSIQFSLNYVHKLREFHIFVVQCQNLAAVDAKRNRSDPYVKSYLIPDPANLGKRKTAVKKKTLNPTYNEILRYRVRMEYLTSQVLNLSAWHNDMFGRNSFLGEIELDLSTWDFNDTERKLLPLKPRNLFIQTTNSLQPSDLKGQMRLAIRFLPQISHSKNVPGSGEVHIWVKDCKNLPLIRSPTIDPYVKCFVLPDTSKKSRQKTRVLKRTTNPIFNHTMVYDGFRAEDLKEACVELTVWDRDRLASHSLGGLRLGMGTGRSYGVQVDWMDSTTEEVALWRRMMNSPNEWVEDILPLRMITAAKNTWK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****.*:****: *:***:*** **:***:*::** : * :::: * ***:****.*::**:*:***:*** ***:::: ::*: *: *..* **. .:*. . *:. : *.**: :.**** * .. * . : * * *:.**...* . :* *:.. *:** . : *:: * .* .:.:* :.: . ::*: . * .* .: **:** ..: :.. :. :: *** :::: .*. . ...* * ** .*: * : :...*:* *::**** * : : * * :*:*: ..* . * : .:**:: *. ::: .* ** :*:: . * .* *:: . * : :.* :: * ** * .: :*.* . : . * ::. *. . :* ::... :: * :** : :: .. . *. . * **: :.*:.. * * *:* . .:::.::: :* .. .*: : . : * *: *.: *:. .. :.*:::*::*****:**:.***. *:* **** : * . .:****. ** *****.**** ***:.*:..::*:*.:**:::**..*:*:*:**.**::***.*.*::*******:**:** .::**:** * ******.*******::. : *.:* **** **.* * *******:****.***::..:.* * * * :*: :: :*:*:**::::*: .*::* :********:* :***:*.. ::.:*** :*****:*******.: :****:***********.*** **********: :*:.: *****:*:***:***.:*******:******.:*:**** *:* *****: ** : ", "identical_positions": 366, "similar_positions": 314, "identity": "21.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-44", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JW23-1", "uniprot_id": "A0A0G2JW23_RAT", "id": "A0A0G2JW23-1", "name": "NACHT, LRR and PYD domains-containing protein 12", "aln": "-------------------------------------------------------------------MLPATAKDALHRLSTYLEELEAGELKKFKLYLG-IAEELGQDKIPRGRMEMAGPLEMAQLMVAHMGTKEAWLLALSTFERIHRKDLWERGQGEDLVRVTPSNGLCSLESQS--------------TCLSDVSPDAPRKDPQITYKDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPIWAQQKLLETGWEHSRTRGHQASPIQMETLFEPDEERPE--PPRTVVLQGAAGMGKSMLTHKVMLDWADGRLFQDQFDYVFYISCRELNRSHTQCSVHDLLSSCWPEHGAPLEDLIRAPDRLLFIIDGFHELHPSFHDVQGPWCHCWEEKRPTELLLGSLIRRLLLPQLSLLITTRPCALEKLHGLLEHPRHVEILGFSEAEREEYFYRYFHNTGQASQVFSFMRDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTSRTTTAVYMFYLLSLMQPKPG-------TPTFKVPANQRGLVSLAAEGLWNQKILFEEEDLGKHGLDGAEVSTFLNVNIFQK----GIKCEKFYSFIHLSFQEFFTAMYCALHGRE------------------AVRRALAEYGFSERNFLAHTVRFLFGLLNEEMRCYLERNLGWTISPQVKEEALAWIQNKARSEGSTLQHGSLELLSCLYEIQEEDFIQQALSHFQ------------------------------------------------VVVVRNLSTKMEHVVCSFCARYCRGTEVLHLYGS----------------------AYSTGAED----------------------------------GPPEPPGAQTQSTHSQERNILPDIYSAYLSA----------------TICTNSNLIELALYRNALGSQGVRLLCQGLRHANCKLQNLRLKRCHISGSACQDLAAAIIAN-RNLIRLDLSGNSIGVLGLELLCEGLQHPMCRLQMIQLRKCLLEAAAGRALASVLSNN-SHLVELDLTGNPLEDLGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMN-QSLMELDLGLNDLGDSGALLLCEGLRHPDCKLQTLRLGICRLGSDACAGVASVLQVN-TCLRELDLSFNDLGDRGLWLLGEGLRHQTCRLQKLWLDSCGLTSKACEDLSSVLGIS-----------------------------------------------------------QTLNELYLTNNALGDTGVRLLCKRLRHPGCKLRVLWLFGMDLN-KVTHRRMAALRVTKPYLDIGC-------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q5R7-1", "uniprot_id": "NAL12_MOUSE", "id": "E9Q5R7-1", "name": "NACHT, LRR and PYD domains-containing protein 12", "aln": "-------------------------------------------------------------------MLPSTARDGLYRLSTYLEELEAGELKKFKLFLG-IAEDLSQDKIPWGRMEKAGPLEMAQLMVAHMGTREAWLLALSTFQRIHRKDLWERGQGEDLVRVTPNNGLCLFESQS--------------ACPLDVSPNAPRKDLQTTYKDYVRRKFQLMEDRNARLGECVNLSNRYTRLLLVKEHSNPIWTQQKFVDVEWERSRTRRHQTSPIQMETLFEPDEERPE--PPHTVVLQGAAGMGKSMLAHKVMLDWADGRLFQGRFDYVFYISCRELNRSHTQCSVQDLISSCWPERGISLEDLMQAPDRLLFIIDGFDKLHPSFHDAQGPWCLCWEEKQPTEVLLGSLIRRLLLPQVSLLITTRPCALEKLHGLLEHPRHVEILGFSEEARKEYFYRYFHNTGQASRVLSFLMDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTPRTTTAVYMFYLLSLMQPKPG-------TPTFKVPANQRGLVSLAAEGLWNQKILFDEQDLGKHGLDGADVSTFLNVNIFQK----GIKCEKFYSFIHLSFQEFFAAMYCALNGRE------------------AVRRALAEYGFSERNFLALTVHFLFGLLNEEMRCYLERNLGWSISPQVKEEVLAWIQNKAGSEGSTLQHGSLELLSCLYEVQEEDFIQQALSHFQ------------------------------------------------VVVVRSISTKMEHMVCSFCARYCRSTEVLHLHGS----------------------AYSTGMED----------------------------------DPPEPSGVQTQSTYLQERNMLPDVYSAYLSA----------------AVCTNSNLIELALYRNALGSQGVRLLCQGLRHASCKLQNLRLKRCQISGSACQDLAAAVIAN-RNLIRLDLSDNSIGVPGLELLCEGLQHPRCRLQMIQLRKCLLEAAAGRSLASVLSNN-SYLVELDLTGNPLEDSGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMN-QSLLELDLGLNDLGDSGVLLLCEGLSHPDCKLQTLRLGICRLGSVACVGIASVLQVN-TCLQELDLSFNDLGDRGLQLLGEGLRHQTCRLQKLWLDNCGLTSKACEDLSSILGIS-----------------------------------------------------------QTLHELYLTNNALGDTGVCLLCKRLRHPGCKLRVLWLFGMDLN-KKTHRRMAALRVTKPYLDIGC-------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A523-1", "uniprot_id": "NLRP3_RAT", "id": "D4A523-1", "name": "NACHT, LRR and PYD domains-containing protein 3", "aln": "----------------------------------------------------------------------MKMMSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCVPIPRGQMEKADHLDLATLMIDFNGEEKAWGMAVWIFAAINRRDLWEKAKKDQPEWNDACTSNLSMVCQEDSLEEE---WIGLLGYLSRISICKKKKDYCKIYRRHVRSRFYSIKDRNARLGESVDLNRRYTQLQLVKEHPSKQEREHELLTIG--RTKMWDRPMSSLKLELLFEPEDEHLE--PVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVS-LRAPKSLADLIISCWPDPNPPVCKILCKPSRILFLMDGFDELQGAFDEHIEEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEILFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGG-------IEEHLFSAYLPGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQK----EVDCERFYSFSHMTFQEFFAAMYYLLEEEEEGVTVRKGPEGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQRQPSQLELFYCLYEMQEEDFVQSAMGHFP------------------------------------------------KIEIN-LSTRMDHVVSSFCIKNCHRVKTLSLG------------------------FLHNSPKE----------------------------------EEEEKRGSQPLD---QVQCVFPDPHVACSS---------------------------------------------------------RLVNCCLTSSFCRGLFSSLSTN-QSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLTHQCCFNISSVLSSS-QKLVELDLSDNALGDFGVRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSN-HSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSLCCSALTSVLKTN-QNLTHLYLRSNALGDMGLKLLCEGLLHPDCKLQMLELDNCSLTSHSCWDLSTILTHN-----------------------------------------------------------QSLRKLNLSNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLN-CETKRTLEALQEEKPELTVVFEISW---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4B8-1", "uniprot_id": "NLRP3_MOUSE", "id": "Q8R4B8-1", "name": "NACHT, LRR and PYD domains-containing protein 3", "aln": "------------------------------------------------------------------------MTSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCIPVPRGQMEKADHLDLATLMIDFNGEEKAWAMAVWIFAAINRRDLWEKAKKDQPEWNDTCTSHSSMVCQEDSLEEE---WMGLLGYLSRISICKKKKDYCKMYRRHVRSRFYSIKDRNARLGESVDLNSRYTQLQLVKEHPSKQEREHELLTIG--RTKMRDSPMSSLKLELLFEPEDGHSE--PVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVS-LRTPRSLADLIVSCWPDPNPPVCKILRKPSRILFLMDGFDELQGAFDEHIGEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEVLFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGG-------IEEHLFSDYLQGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQK----EVDCERFYSFSHMTFQEFFAAMYYLLEEEAEGETVRKGPGGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQWQPSQLELFYCLYEMQEEDFVQSAMDHFP------------------------------------------------KIEIN-LSTRMDHVVSSFCIKNCHRVKTLSLG------------------------FFHNSPKE----------------------------------EEEERRGGRPLD---QVQCVFPDTHVACSS---------------------------------------------------------RLVNCCLTSSFCRGLFSSLSTN-RSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLSHQCCFDISSVLSSS-QKLVELDLSDNALGDFGIRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSN-HSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSICCSALTSVLKTN-QNFTHLYLRSNALGDTGLRLLCEGLLHPDCKLQMLELDNCSLTSHSCWNLSTILTHN-----------------------------------------------------------HSLRKLNLGNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLN-RETKRALEALQEEKPELTIVFEISW---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M918-1", "uniprot_id": "F1M918_RAT", "id": "F1M918-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MKTEDEEMEDQLSKEEIVSED------------------------------------KEFD----YRTIIKENFFIIWDKTSLLGESATLN-------------------------------CVTTHKDQKLLEHIFDVNIQTSK--SPQTVVLYGAAGIGKTTLLKKAVLEWADGNLYQ-QFTHVFYLSGREIS-QEKEKNFAQLISKHWPSSEGPIEQILCKPSSLLFILDSFDELDFSFEEPEFALCRDWTQKHPVSFLISSLLRKVMLPESYLLVTTRTTAWKRLVPLLQKPHRVKLPGLSRSSRIDYIHHLLKDKTWAMNAVCSIRMNAKLFNMCHVCHVCQMICTFLKEQVEKGGNVEMTCQTSTALFTYYICSLFPRIAGS------SVTLPNETLLRSLCQAAVEGIWTMKHVLYQQNLRKHELTREDLSLFLEANVLQQ----DTECENCYTFTHLQVQEYFAALFYLLRENPEEKDHPLEP--------FENVHLLLESNHFHDPHLEQMKCFLFGLLNKDRVQQLEETFNLTISRAVREELLVCLEALEKDDSPLSQLRIQDLLHCIYETQDEEFITQALTYFQ------------------------------------------------KIMVK-VDEESKLLIYSYCLKHCHSLQTVRLTAR----------------------ADLRNMLDPTAEICLEDAAVRIIHYWQDLFSVLHTNESLLEMDLYESRLDESLMKILNEEFSHPKCNLQKVMFRAVCFLN---SCYDFSFLAFNNTVTHLDLKDTDLGDNGVKTLCEALKYQGCKLRVLRLESCDLNVTHCQNLSKALQSN-RSLVFLNLSTNSLSNDGVKSLCEVLENPNCPLERLALASCGLTKVGCEVLSSALTKT-KRLTHLCLAHNVLEDEGIELLSYTLRHPRCTLQSLVLRCCYFTPIGSEHLSTALQNN-KSLIHLDLGFNKLADSGVKLLCQTLQQPNCNLQELELMGCVLTSEACGDLASVLVNN-SNLWNLDLGNNILDDAGLNILCEALRNPNCQIRRLGLENCGLTPGCCQDLLDLLSNN-----------------------------------------------------------QSVIQMNLMKNSLDYEAIRNLCKVLRSPTCKMEFLALDKKDLFKKKIKKFLVDVRINNPHLVIRPQCPNTESGCWWQYF-----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6B966-1", "uniprot_id": "NAL14_MOUSE", "id": "Q6B966-1", "name": "NACHT, LRR and PYD domains-containing protein 14", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------MKTEDDEMEYEASKEETVSED------------------------------------KDFDDGIDYRTVIKENIFTMWYKTSLHGEFATLN-------------------------------CVITPKDQNLLQHIFDEDIQTSE--APQTVVLQGAAGIGKTTLLKKAVLEWADGNLYQ-QFTHVFYLNGKEIS-QVKEKSFAQLISKHWPSSEGPIEQVLSKPSSLLFIIDSFDELDFSFEEPQFALCKDWTQISPVSFLISSLLRKVMLPESYLLVATRSTAWKRLVPLLQKPQRVKLSGLSKNARMDYIHHLLKDKAWATSAIYSLRMNWRLFHMCHVCHMCQMICAVLKGQVEKGGRVEETCKTSTALFTYYICSLFPRIPVG------CVTLPNETLLRSLCKAAVEGIWTMKHVLYQQNLRKHELTREDILLFLDAKVLQQ----DTEYENCYMFTHLHVQEFFAALFYLLRENLEEQDYPSEP--------FENLYLLLESNHIHDPHLEQMKCFLFGLLNKDRVRQLEETFNLTISMEVREELLACLEGLEKDDSSLSQLRFQDLLHCIYETQDQEFITQALMYFQ------------------------------------------------KIIVR-VDEEPQLRIYSFCLKHCHTLKTMRLTAR----------------------ADLKNMLD-TAEMCLEGAAVQVIHYWQDLFSVLHTNESLIEMDLYESRLDESLMKILNEELSHPKCKLQKLIFRAVDFLN---GCQDFTFLASNKKVTHLDLKETDLGVNGLKTLCEALKCKGCKLRVLRLASCDLNVARCQKLSNALQTN-RSLVFLNLSLNNLSNDGVKSLCEVLENPNSSLERLALASCGLTKAGCKVLSSALTKS-KRLTHLCLSDNVLEDEGIKLLSHTLKHPQCTLQSLVLRSCSFTPIGSEHLSTALLHN-RSLVHLDLGQNKLADNGVKLLCHSLQQPHCNLQELELMSCVLTSKACGDLASVLVNN-SNLWSLDLGHNILDDAGLNILCDALRNPNCHVQRLGLENCGLTPGCCQDLLGILSNN-----------------------------------------------------------KSVIQMNLMKNALDHESIKNLCKVLRSPTCKMEFLALDKKEILKKKIKKFLVDVRINNPHLVIGPECPNTESGCWWNYF-----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P59047-1", "uniprot_id": "NALP5_HUMAN", "id": "P59047-1", "name": "NACHT, LRR and PYD domains-containing protein 5", "aln": "---------------MKVAGGLELGAAALLSASPRALVTLSTGPTCSILPKNPLFPQNLSSQPCIKMEGDKSLTFSSYGLQWCLYELDKEEFQTFKELLKKKSSESTTCSIPQFEIENANVECLALLLHEYYGASLAWATSISIFENMNLRTLSEKARDDMKRHSPEDPEATMTDQGPSKEKVPGISQAVQQDSATAAETKEQEISQAMEQEGATAAETEEQEISQAMEQEGATAAETEEQGHGGDTWDYKSHVMTKFAEEEDVRRSFENTAADWPEMQTLAGAFDSDRWGFRPRTVVLHGKSGIGKSALARRIVLCWAQGGLYQGMFSYVFFLPVREMQ-RKKESSVTEFISREWPDSQAPVTEIMSRPERLLFIIDGFDDLGSVLNN-DTKLCKDWAEKQPPFTLIRSLLRKVLLPESFLIVTVRDVGTEKLKSEVVSPRYLLVRGISGEQRIHLLLERGIGEHQKTQGLRAIMNNRELLDQCQVPAVGSLICVALQLQDVVGESVAPFNQTLTGLHAAFVFHQLTPRGVVRR----CLNLEERVVLKRFCRMAVEGVWNRKSVFDGDDLMVQGLGESELRALFHMNILLP----DSHCEEYYTFFHLSLQDFCAALYYVLEGLEIEPALCPLY-------VEKTKRSMELKQAGFHIHSLWMKRFLFGLVSEDVRRPLEVLLGCPVPLGVKQKLLHWVSLLGQQPNATTPGDTLDAFHCLFETQDKEFVRLALNSFQ------------------------------------------------EVWLP-INQNLDLIASSFCLQHCPYLRKIRVDVKGIF-------------------PRDESAEACPVVPLWMRDKTLIEEQWEDFCSMLGTHPHLRQLDLGSSILTERAMKTLCAKLRHPTCKIQTLMFRNAQITPG--VQHLWRIVMANRNLRSLNLGGTHLKEEDVRMACEALKHPKCLLESLRLDCCGLTHACYLKISQILTTS-PSLKSLSLAGNKVTDQGVMPLSDALRVSQCALQKLILEDCGITATGCQSLASALVSN-RSLTHLCLSNNSLGNEGVNLLCRSMRLPHCSLQRLMLNQCHLDTAGCGFLALALMGN-SWLTHLSLSMNPVEDNGVKLLCEVMREPSCHLQDLELVKCHLTAACCESLSCVISRS-RHLKSLDLTDNALGDGGVAALCEGLKQKNSVLARLGLKACGLTSDCCEALSLALSCN-----------------------------------------------------------RHLTSLNLVQNNFSPKGMMKLCSAFACPTSNLQIIGLWKWQYP-VQIRKLLEEVQLLKPRVVIDGSWHSFDEDDRYWWKN----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ANC0-1", "uniprot_id": "A0A8M3ANC0_DANRE", "id": "A0A8M3ANC0-1", "name": "", "aln": "MDSRKRRSSSPESSCVSIKSDASMDNPPTLRLGESPAKHRRSSSLGSSCVSMKSDASMDNPPTLRLGESPAKHRRSSSPESSCVSMKSDASMDNPPTLRLGESPAKHSDNQKRSQSNKGQKQLDAIFKDLEETNIDEMRKVLRRFKMLLSPDYSVRDEEEEEGQRQINEAFLKITLHALQKMN--------QTDLASKLQTKLISVSQQQLKSRLKQRFERFTEGVSNRGNTKLLNDIYTEVYITEGGAGNIDDEHEVRQIET---SSSRFPEIPIRCCDIFKSLLGQDK--AIRTVLTKGVAGIGKTASVQKFILDWAEG-KANQDVHFIFPLPFRDLNLIKEKRMSLMELLCCFCPELKPIDYNN---FKTVFIYDGLDEWRLPLDFRNNEILWDMNKVASVDALLTNLLQGNLLPSAVHWITTRPAAACQIPAEFID-RVTEVRGFKDLQRAEYFWKRIKDQNLANKIITHIQSSRSLHIMCRIPVFCWISATVLEKIFGEAN-SADIPKTLTQMFIHLLIVQTNLKTQKYDRECDVNLEKARKSILSLAKLAFEQLEKGNLIFYEEDLKQCGIDVREASVCSGVCTQIFREEFGLQLQKVFSFVHLSVQEFLAALFKFLSFAEENNKSSMTQ---------FMKNEVDRALQSPNGHLDLFLRFLLGLSLDSNQTLLQGLFTPLDTSHSRDETIEYIKSKIRENPS--PERSINLFYCLNELNDHSLVQEVQTYLTSTRSHRLSGVKLSPALWSALVFVLLNSTKDLDEFELRQYDFTEECLLRLLPVVKASRKADLKGGNLTDQICSALASALSSSSCCLRELDLSENRLQLSGIRLFSAGLKSPNCKLEILKLSNCSIREEGCASLVSALLSNPSHLRELNLNSNQPGYSTVKLLSDLLENPHCKLEKLQLYNCCIGEEGCAALALALISNPSHLRELNLNNNEPGDSGVKLLSDLLKDPRCKLEKLQLNGSNIREKDCAAFISSLLSNPFHLRELSLSWNKPGDSGVKLLSDLLKDSRCKLEKLELECCSIIEEGCAALALALVSNPSHLRELNLNNNEPGDLGVNLLSFLLKNPQCKLEKLELEYCCIGAKSCASLASAFVSNPSHLRELNLNWNTPEYPAVKLLSDYLKDPHCKLEKLQLYNCCIGEEGCAALALALISNPSHLRELNLNNNEPGDSGVKLLSDLLKDPRCKLEKLQLEYCCIGEEGCAALVSGLKSNPSHLRELNLNRNEPGNLGAKMLSDLLKDPLFELEKLELDDCSIENNGFADLVSGLKSNPSNIRELNLNSNKFIFSGLNLLCDLLRDQQCKLRKLQLECCNIDEEGCAALALALISNPSHLRELNLNYNNPGGLGVKLLSVLLKNPHCKLEKLELSHCSISENYLAALNSALSSNPAHLRELNLNYNENTRQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7N0-1", "uniprot_id": "A1Z7N0_DROME", "id": "A1Z7N0-1", "name": "Leucine-rich repeat-containing protein 34", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCDVLLPCEYNPKECPSPAAEKSRLFTILLLYCWQREYDKRPYRQFQFKRLTFEERIGRRYHCIRDLRIIVNYLLRRPQLSVQISSLVVSNWDAGLLKDFVRSLLPVWYIELRLMRFPREF----------------------FVMLRLNAAKMNVSQLSLEGTPLTDEDVRILREFLLVSK-----------------------------------------------------------------------------------------------------------------------TLRRLNVSSCSLTQFNFALIADGVYKSP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GVRRLSANRLLG---------MSLSLDTEKISS----VLSSLLMQN--TLWALSLEHCELTAQDMIPIAEHLARTNSKFRRLRIACNKIGPDGAFFLLRGMSMG-GNLELLDLSYCSIGTHGGEWVAKYLASC-RRLQVLHLNYNDMGPTAVNLILLAMKK-QCKLEKLTLYGNHFDSRTAMIVRRLLDAEVVLHSELDISYT---------YDEALQDYRVVPWR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :** . : . . . : : : * . :: : : . : : . .* : : : * : :: : : *.* :. *.. * : : * * : :: * . : .* : * * :* : *. * * * : :: : * * :. * .. :: : . *:*: * * : . : : . * : . : * . ", "identical_positions": 29, "similar_positions": 68, "identity": "2.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-51", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q920A7-1", "uniprot_id": "AFG31_MOUSE", "id": "Q920A7-1", "name": "Mitochondrial inner membrane m-AAA protease component AFG3L1", "aln": "MLLRLVGAAGSRALAWPFSKLWRCGGCAGSGGTVWSSVRACGIALQGHLGRCSQQLALQGKLTSFSPRLYSKPPRGFEKFFKNKKNRKSASPGNSVPPKKEPKNAGPGGDGGNRGGKGDDFPWWKRMQKGEFPWDDKDFRSLAVLGAGVAAGFLYFYFRDPGKEITWKHFVQYYLARGLVDRLEVVNKQFVRVIPVPGTTSER--FVWFNIGSVDTFERNLESAQWELGIEPTNQAAVVYTTESDGSFLRSLVPTLVLVSILLYAMRRGPMGTGRGGRGGGLFSVGETTAKILKNNIDVRFADVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAMLTGPPGTGKTLLAKATAGEANVPFITVNGSEFLEMFVGVGPARVRDMFAMARKHAPCILFIDEIDAIGRKRGRGHLGGQSEQENTLNQMLVEMDGFNSSTNVVVLAGTNRPDILDPALTRPGRFDRQIYIGPPDIKGRSSIFKVHLRPLKLDGSLSKDALSRKLAALTPGFTGADISNVCNEAALIAARHLSPSVQERHFEQAIERVIGGLEKKTQVLQPSEKTTVAYHEAGHAVVGWFLEHADPLLKVSIIPRGKGLGYAQYLPREQFLYTREQLFDRMCMMLGGRVAEQLFFGQITTGAQDDLRKVTQSAYAQIVQFGMSEKLGQVSFDFPRQGETMVEKPYSEATAQLIDEEVRCLVRSAYNRTLELLTQCREQVEKVGRRLLEKEVLEKADMIELLGPRPFAEKSTYEEFVEGTGSLEEDTSLPEGLKDWNKGRE-EGGTERGLQESPV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F6D6-1", "uniprot_id": "E7F6D6_DANRE", "id": "E7F6D6-1", "name": "", "aln": "-------------MAALLSASLRG---------------AARTALRFHTARIRSCAAHP----PFSGLYGVSPLRSVGKRFTFPQSCYSTDAPKDAPPPG-------GGGGGRRGGRKS---WPARLAQGDFPWDDRDFRHLLLAASGVAALLLYLLFRDPGKEITWKDFVHRYLDRGLVERLEVVNKQFVRVILERDADANEGSYVWFNIGSVDTFERNLEAAHYELGLEPSHRAAVVYTSESDGSFLMSFIPTLLLIGFLLFTLRRGPMGGGMGGRRGGLFGMSESTAKMMKDSIEVKFKDVAGCEEAKVEIMEFVNFLKNPQQYQDLGAKIPKGAVLSGPPGTGKTLLAKATAGEANVPFITVNGSEFLEMFVGVGPARVRDMFALARKNAPCILFIDEIDAVGKKRGGGNFGGNSEQENTLNQLLVEMDGFNSSTNVVVLAGTNRPDVLDPALMRPGRFDRQIYLGPPDIKGRASIFKVHLRPLKLDPSVDRDAIARKMAAATPGFTGADIANVCNEAALIAARYLNESVSVKHFEQAIDRVIGGLEKKTQVLQPTEKKTVAYHEAGHAVVGWFLQHADPLLKVSIIPRGKGLGYAQYLPKEQYLYTREQLFDRMCMMLGGRVAEQVFFNKITTGAHDDLKKVTQSAYAQIVQFGMSERVGQVSFDLPRQGETVLEKPYSEATAELIDEEVRDLVDRAYRRTLELVTEKREQVDMVGKRLLEKEVLDKADMLELLGARPFEEKSTYEEFVEGTGSFEEDTSLPEGLKDWNQERRGEPEEPTDSQEQRAA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :* * *. **: * .* . * .** .* *.. * *. :. *:.. :..** **.**.***: . * *: :*:*****:*** * : .:**** :**: ***********.**: ** ****:************* .: ::. :****************:*::***:**:::******:******* *::***:*:.:**:::****** * *** ****.:.*:***::*:.*:*:* *********:************:*************:*:***********************************************:***:************:*:*** *::**:*********:***********************:***** **********:********:************* *:.:**::**:** *********:************:*. **. :******:***************:**.****************:************************:**:**********************:**.:*****:***:*****************::******:******::*********:******* ** **.*****:*: ****: **:********:****:****.*** **************:**************: *. * . **. . ", "identical_positions": 551, "similar_positions": 125, "identity": "69.48%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-52", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07154-1", "uniprot_id": "CATL1_RAT", "id": "P07154-1", "name": "Procathepsin L", "aln": "------------------------------MTPLLLLAVLCLGTALATPKFDQTFNAQWHQWKSTHRRLYG-TNEEEWRRAVWEKNMRMIQLHNGEYSNGKHGFTMEMNAFGDMTNEEFRQIVNGYRH--QKHK-------KGRLFQEPLMLQIPKTVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHDQGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGS-CKYRAEYAVANDTGF-VDIPQ-QEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKDLDHGVLVVGYGYEGTDSNKDKYWLVKNSWGKEWGMDGYIKIAKDRNNHCGLATAASYPIVN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06797-1", "uniprot_id": "CATL1_MOUSE", "id": "P06797-1", "name": "Procathepsin L", "aln": "------------------------------MNLLLLLAVLCLGTALATPKFDQTFSAEWHQWKSTHRRLYG-TNEEEWRRAIWEKNMRMIQLHNGEYSNGQHGFSMEMNAFGDMTNEEFRQVVNGYRH--QKHK-------KGRLFQEPLMLKIPKSVDWREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGGLMDFAFQYIKENGGLDSEESYPYEAKDGS-CKYRAEFAVANDTGF-VDIPQ-QEKALMKAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVVN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07711-1", "uniprot_id": "CATL1_HUMAN", "id": "P07711-1", "name": "Procathepsin L", "aln": "------------------------------MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYG-MNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQN--RKPR-------KGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEES-CKYNPKYSVANDTGF-VDIPK-QEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O60911-1", "uniprot_id": "CATL2_HUMAN", "id": "O60911-1", "name": "Cathepsin L2", "aln": "------------------------------MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYG-ANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRN--QKFR-------KGKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEI-CKYRPENSVANDTGFTVVAPG-KEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZJV2-1", "uniprot_id": "D3ZJV2_RAT", "id": "D3ZJV2-1", "name": "", "aln": "------------------------------MTPIFLLATLCLGMISAAPTHDPSFDTVWEEWKTKHGKTYN-TNEEGQKRAVWENNMKMINLHNEDYLKGKHGFSLEMNAFGDLTNTEFRELMTGFQG--QKTK-------MMKVFPEPFLGDVPKTVDWRKHGYVTPVKNQGPCGSCWAFSAVGSLEGQVFRKTGKLVPLSEQNLVDCSWSHGNKGCDGGLPDFAFQYVKDNGGLDTSVSYPYEALNGT-CRYNPKYSAAKVVGF-MSIPP-SENALMKAVATVGPISVGIDIKHKSFQFYKGGMYYEPDCSSTNLNHAVLVVGYGEE---SDGRKYWLVKNSWGRDWGMDGYIKMAKDWNNNCGIASDASYPIV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9QBE2-1", "uniprot_id": "E9QBE2_DANRE", "id": "E9QBE2-1", "name": "Cystein proteinase inhibitor protein salarin", "aln": "-------------------------------MMFALLVTLYISAVFAAPSIDIQLDDHWNSWKSQHGKSYH-EDVEVGRRMIWEENLRKIEQHNFEYSLGNHTFKMGMNQFGDMTNEEFRQAMNGYKHDPNRTS-------QGPLFMEPKFFAAPQQVDWRQRGYVTPVKDQKQCGSCWSFSSTGALEGQLFRKTGKLISMSEQNLVDCSRPHGNQGCNGGLMDQAFQYVKENKGLDSEQSYPYLARDDLPCRYDPRFNVAKITGF-VDIPKGNELALMNAVAAVGPVSVAIDASHQSLQFYQSGIYYERACTS-QLDHAVLVVGYGYQGADVAGNRYWIVKNSWSDKWGDKGYIYMAKDKNNHCGIATMASYPLM-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q95029-1", "uniprot_id": "CATL1_DROME", "id": "Q95029-1", "name": "Cathepsin L1", "aln": "MNHLGVFETRFRPRTRHKSQRAQLIPEQITMRTAVLLPLLALLAVAQAVSFADVVMEEWHTFKLEHRKNYQDETEERFRLKIFNENKHKIAKHNQRFAEGKVSFKLAVNKYADLLHHEFRQLMNGFNYTLHKQLRAADESFKGVTFISPAHVTLPKSVDWRTKGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNGGIDTEKSYPYEAIDDS-CHFNKGTVGATDRGF-TDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTD---ESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : : . . . * :* * : * * : ::::* : * ** : *: *.: :* :.*: ***: : :. .: * .* *: **** :* **.**:* *****:**: *.**** * *:* *:.:********* **:**:**: **:*:::* *:*:. **** * : *:: *. ** * .* : :***:***:**.:* * *: **. *:* * * : :::*.**:**:* : **:*****. ** *:: : :: *:**:*: :*** : ", "identical_positions": 118, "similar_positions": 84, "identity": "31.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-61", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VSE7-2", "uniprot_id": "MTH7_DROME", "id": "Q9VSE7-2", "name": "Probable G protein-coupled receptor Mth-like 7", "aln": "--------------MRLPWVIFCTVLLLIFT---------------NNSNADIPGCNYYDTVDIS-YIERQNDSYLYDDIEIPASLTGYYEFRQFGDGSITPIEK-HLRACVCSVRPCIRICCPAKNFLANGKCDDGLKEELARFKPYIYFTYMDLQARVPLTDMAIIRDEFFDCDEMIYISDFNYFLEEVSIQIFN--KCGLIVWFQDGKFWVTVD-LFMEKQDYCLYR------HNFDSDFPKSMWIIRHRCTSHISPGSLEILIITMICFVLTIAVYLYIKKLRN-VTGKC-IVCCIVSRFIQCLIMILDHLN-LLNG---ICSPAGYSSHFFRMASNLWLSVISYHTWKVLT---SLNRVDPNYRFLRYNAFVWSTAAIMTGSIYIVNQIWENDPSKWNWLPLVG-FIRCSVKDWHPSVWIYISGPSLALSTFNVAMFALTAIYIRKVKGGINKFTNE-----------------------EEGRINCINF---------DSQTYLQFLRLSIVMGLTWIFNVIP-YSARLHIFWEWVGI-ISEYFHSAFGI------------------------------------VLFVLLVLKR-STWTLMMDS------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P83119-1", "uniprot_id": "MTH12_DROME", "id": "P83119-1", "name": "Probable G protein-coupled receptor Mth-like 12", "aln": "--------------MFLWLKCFCTLIIVTIA---------------KNSSAKIPHCKYDETINIS-HFKRLNDAYIYEHFEIPANLTGEFDYKELMDGSKVPTEFPNLRGCICKVRPCIRICCARKNILSNGECSDGVKNEIK--LTMLDLTMQDILLTDPTLAELNMIPQYNSTELLILREQFQPCDEIVSLK-----RDEYTILKDGSILLHTSA-EILSNDQYCLYP------EIY-SDFPETIRIINRRCYRNVMPGIAQLSVISVVGFILTLAVYLSVEKLRN-LLGKC-LICSLFSMFMEYFIWTMDYFR-LLQS---ICSAAGYMKYFFSMSSYLWFSVVSFHLWELFT---SLNRHEPQYRFLIYNTFVWCTAAIPTVVIFSMNQMWENDPGKSEWLPLVG-YFGCSVKDWNSSSWFYSHIPIVILNSFNVIMFVLTAIYIWKVKKGVKSFAQH-----------------------DERNTTCLEF---------NVQTYIQFVRLFLIMGASWLLDQLTRLAEDSHLLLDTIVLNLTVYLNAAFGI------------------------------------LIFVLLILKG-STFKMIMER------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "V9H0I1-1", "uniprot_id": "V9H0I1_DROME", "id": "V9H0I1-1", "name": "", "aln": "----------------MKLQLLGTFLVLILL---------------QFQAVNT---DSNKTEEDS-CVKSDDDNSNDED----------------------------------DLWHCIPICCPRKNMMANGGCS---------FKEHLFRTKLDLNIRLDD----NSTEALYFNNQTLLITSFWDIDEMMGLR-----RDEYTLYKNGTIYIHSDQ-SIQTKEEYCFYP------HQIYSDFPETIWIISHKFSSIESPGAFELASGSIICYIIIFGIYLFVKELRN-DFGKC-VMSCVFCLFLDYLIWLMDELR-LLDD---FCSLTGYIMFFFDFANSVWFSIISYCIWKKIT---SVVSQENRDQFVFYSTFAYGISAIPLGIIISINQFWEEDLRKWNWLPLVG-FSRCSVDDCKRSSWVYYFVPYAIMCAINIIMFVLTIKHIMKTKRNLHNLTKR-----------------------PDRNETCVTVN------FLNFELYLLFLRISGIMGVAWILIIFLLIEVN-STFWDIFGI-IIQQIHYGFGI------------------------------------ILFVLLIFKR-STHQLLIAK------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS77-1", "uniprot_id": "MTH6_DROME", "id": "Q9VS77-1", "name": "Probable G protein-coupled receptor Mth-like 6", "aln": "----------------MLLNILAIILVFVIS---------------SQSEAVIPGCDYFDTVDIS-HIPKLNDSYAYEELIIPAHLTGLYTFRQLADGSQEPVKS-HLRACICKLKPCIRFCCPRNKMMPNSRCSDG-------LTENLKRINPYLKITLEDG---TIGKYYLLTDMIVLRYEFRYCEKVVSVQ-----EDQYKLYENGSFMIKPDVNWTLSKQWYCLHP------RLE---DPNSIWILEHVYIPKSMPAVPQVGTISMVGCILTIAVYLYIKKLRN-LLGKC-FICYVFCKFVQYLIWAGGDLN-LWNN---ICSLAGYTNYFFALASHFWLSVMSHQIWKNLR---LINRDERSYHFLIYNIYGWGTPAIMTAITYLVDWAWEDRPDKLNWIPGVG-LYRCWINTYDWSAMIYLYGPMLILSLFNVVTFILTVNHIMKIKSSVKSSTQQ-----------------------QRK---CIQN-----------NDFLLYLRLSVMMGVTGISEVITYFVKR-HKFWRQVLR-VPNFFHLGSGI------------------------------------VVFVLFILKR-STFQMIMERISGPRRQQPAS-------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0R5-1", "uniprot_id": "MTH10_DROME", "id": "Q9W0R5-1", "name": "Probable G protein-coupled receptor Mth-like 10", "aln": "MPKKIHQPGGSLYCGVTLLGVLCLVVFRLIPGIPFGTYVMAERDHYHTIDDPNVPCNFYDTVNLTGHRLFPNGSYDYYGTIVPAELVGTYDYIHSSLTERIEVRE-HVRGCVCKFKSCLNICCPWRQVFNSEVDG-------CIIDHSDNRTWPDPPMLNITFR--NESTILVNMFTQFAIQSFRPCPKMFSLQPETNNWDDYLLFENGSMLRVDDK-LLIRKNEFCMVPTYVNESDMFYTIHPANCDMQDDHSTVKIIN--SYAMMFSIPFMMLTIAVYLLIPELRN-QHGKS-LVCYLIGLSVGYSSLCYVQLY-QVDATGVTCKVFGYTAYFFFMGAYMWLSVISFDLWHNFRGTRGINRFQEKKRFLFYSLYSWGIALVFLAFTYCAQQLTN---LPANLKPGIGDGVYCWLDMSNWAAMIYFYGPILAIVVANTIMFIMTAIKIHGVQREMARIIAS-----------------------ENSTKNLRTEKDKRFYRAWSNYRFGLFLRLFLIMGITWLTELISYFVGS-DKGWSKLFY-ISDLANAMQGF------------------------------------LIFMLFVMKK-KVKHLITNRCSSVRDGSNQRQSQYSTKTTSSSVANLSLHEKPSVEKPLVISSSVDPQKTTIFR------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0R6-1", "uniprot_id": "MTH9_DROME", "id": "Q9W0R6-1", "name": "Probable G protein-coupled receptor Mth-like 9", "aln": "--------------MVSPLIILLIIWLSVGAKS-------------VEIASINHPCAYAHTVNITDGLRMKDGSYSYAGVVVPPHLMAEYSFKVIDGVEYRAKKH--LRGCVCLLKPCISFCCPENLVFDAKHWN--------CTMPHQVRESTHVELTYAN----RTVDQVRIRDRFVVRTELGCRNKFVDKKHDN--FWQWDLFENG-TLRRDNR--LWSTDEYCFSP-----LEHNPEQWELTPLNCERFQTGYRVWIYAICSIIAIIINIFILSLLGSVRDARKSHYGQL-IIYYLLSMIVGYSLLVYLALKNPMKLSHVACRNIGFLAYFCIMLSFVFLAICSLDFLLKFK---------QKAVRSSVRRLSLALAVLAVIGLRFLVSLAQDSKLPKHFKPGMG-EDYCWFDVRTWGILIYYYGPIALLLIFSIVCCLKAYFSIYELPPDTQYILGT-----------------------QLKIVKTHFYAFS-AYIVGVFAVWIREIVVYIMARVREHFFIIDFWSGICILGLAIAGFILLLGKNLHVKS------------------------------------WWAINVESSQ-TDLSIINARVYKFDEKGDLKSSDSPYKPTVTSL------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0AC58FZP1-1", "uniprot_id": "A0AC58FZP1_DANRE", "id": "A0AC58FZP1-1", "name": "", "aln": "-----MENVKISLSIVPQKAVDCGWIWAVFYRQ-------------PDAEKKEDKHSSQNRQSFNCADKALQLMLVAYNIAIGQCQKSYYCSPLANTSTCANTSSYVERACLGQNTACMAYSCNSKSSGCSCKLGSYNCSINCNYDIYSDLCDCRADTHSCTCLGDMTTSVGSPNQTVASTTNLLNLISNMSGQLSPTDAGNFLSVVDAAQMKVSTSDSPVEKSTLVSFG--NAYLNAFENLVSALVVATDNMTVKNIALNNTEVTVLAIGVNASAADIPPIYTKTAQLEIDLIGIAKQSISKSASVAFVSYSAMDSILKPDFFNTSENTVKTMMSTVISATLSQTNNTALTKPVN--FTLKHIQGFNPKSSLSCVYWNDSEWIVDGCSVLNSNSSHTVCSCVHLSTFALIMQTSSTPPESSDLLELLNLVCVIVGLVFFSLALLSFALCQWSPGVNNVARINICISLLSAHLLFLLTQQFLSLIRPQQVFCVAIAGLLHFLFLSAFVWMFIEAVLLFICVQNLSRISSKKKEVLSSGFLCVIGYVLALVVVGVSIGLVPEGYGSEQCWIKTAEGFIWSFLGPVCVILALNTIFFIKIVLTLNSTLKNLNAEVSQMKQTKILAFKTLSQFVVLGCPWILGFFINGSEVLEILFLVLNSQQGTFIFVIYCVLNNEIRQQYKNCFTCLCSGHSIKCNK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : *: .* . . .: . .. : : .. :: : . : . . . : . : . . . . . . .. . . : : : : . : : . . . : ", "identical_positions": 2, "similar_positions": 49, "identity": "0.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-63", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q15238-1", "uniprot_id": "PSG5_HUMAN", "id": "Q15238-1", "name": "Pregnancy-specific beta-1-glycoprotein 5", "aln": "--------------------MGPLSAPPCTQHITWKGLLLTASLLN---------FWNLPITAQVTIEALP------------------------PKVSEGKDVLLLVHNLPQN-LAGYIWYKGQLMDLYHYITSYVVDG--QINIYGPAYTGRETVYS-------------NASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKS--ENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGP----------------------DLPSIYPSFTYYRSGENLYLS-------------CFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYTCSVRNSATGKESSKSMTVEVSAPSGIGRLPLLNPI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11465-1", "uniprot_id": "PSG2_HUMAN", "id": "P11465-1", "name": "Pregnancy-specific beta-1-glycoprotein 2", "aln": "--------------------MGPLSAPPCTEHIKWKGLLVTASLLN---------FWNLPTTAQVTIEAQP------------------------PKVSEGKDVLLLVHNLPQN-LTGYIWYKGQIRDLYHYITSYVVDG--QIIIYGPAYSGRETAYS-------------NASLLIQNVTREDAGSYTLHIIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETVILTCDPET--PDTSYQWWMNGQSLPMTHRFQLSETNRTLFLFGVTKYTAGPYECEIRNSGSASRSDPVTLNLLHGP----------------------DLPRIHPSYTNYRSGDNLYLS-------------CFANSNPPAQYSWTINGKFQQSGQNLFIPQITTKHSGLYVCSVRNSATGEESSTSLTVKVSASTRIGLLPLLNPT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z652-1", "uniprot_id": "A0A8M6Z652_DANRE", "id": "A0A8M6Z652-1", "name": "", "aln": "MFCVFSLIFLLVIPGVCRQKWGVKYSKMAICALKSSTIHLSGSYTHPYGLTVTKIFWTVNPKIGESINLLDNSNYTGRVEYFDKDKFFFVKLSNVRQEDEGMYCLRIETKVEKERHLGYPGIELTVTELRVETPEEVVEGDSPVLICKSSCNLGSTNFSWYKNGESFSKWVGENQLILQSVSREDSGNYSCAVRDLKDLP---SPALTLNVRYPPKSVSVSVSGSAVIVSGDSVTLSCSSDSNPPALNFSWFKENQSSAIGS-------GQSFSISSFNTNHSGRYYCEAHNKYGSLRSASVSLTAKDGQNTLLYAAAGFGAAFICICIIIVALKIIRRKTADAEVQGDLSKQENKSTAVMDQMNSCDPDTGHQNDVMYASVCQKRPKEHQTAGDEDDVQYASVHHVRNADKVTAEDESQYGSASNCRLDDSSVIYSSIGVS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . :. . : ::.* : **.: . :*: : .** * : :: :: ** : : :* .. **:* : * .: . .* :* : .*::*.*:***:*.*: : . * . : :*:.: . :: .. : : ::*...: .: *: :.** .: .: : : ... :* * ** :: .. ** .*:*. * * * . : . :* . * .::. : :: : : . :: : .:: .:: :..*.::.* :.. . . : ", "identical_positions": 46, "similar_positions": 123, "identity": "10.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-64", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62956-1", "uniprot_id": "ERBB4_RAT", "id": "Q62956-1", "name": "Receptor tyrosine-protein kinase erbB-4", "aln": "----------------MKLATGLWVWGSLLVAARTVQPSASQ---------------------------------------------------------SVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEH-NRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNMTLVSTIGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDG-RCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHG--DPYN------AIDAIDPEKLNVFRTVREITGFLNIQTWPPNMTDFSVFSNLVTIGG-RVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTVNQRIVIRDNRRAENCTAEGMVCNHLCSNDGCWGPGPDQCLSCRRFSRGKICIESCNLYDGEFREFENGSICVECDSQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCP-----------------DVLQG----------------------------------ANSFIFKYADQD--------------RECHPCHPNCT---------------------------------------------QGCNGPTSHDCIYYP---------------------------WTGHSTLPQHARTPLIAAG------------------VIGGLFILVIMALTFAVYVRRKSIKKK----RALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASVDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYIVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPN---DSKFFQNLLDEED-LEDMMDAEEYLVPQAFNIPPPIYTSRTRIDSNRSEIGHSPPPAYTPMSGSQFVYQDGGFATQQGMPMPYTATTSTIPEAP-VAQGATAEMFDDSCCNGTLRKPVVPHVQEDSSTQRYSADPTVFAPERNPRAELDEEGYMTPMHDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHSASSGPPKAEDEYVNEPLYLNTFTN------------------------------------------------------ALGNAEYMKNSLLS-----------------------------------------------------------VPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTMLPPPPYRHRNTVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61527-1", "uniprot_id": "ERBB4_MOUSE", "id": "Q61527-1", "name": "Receptor tyrosine-protein kinase erbB-4", "aln": "----------------MKLATGLWVWGSLLMAAGTVQPSASQ---------------------------------------------------------SVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEH-NRDLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNMTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDG-RCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHG--DPYN------AIDAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGG-RVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRRAENCTAEGMVCNHLCSNDGCWGPGPDQCLSCRRFSRGKICIESCNLYDGEFREFENGSICVECDSQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCP-----------------DGLQG----------------------------------ANSFIFKYADQD--------------RECHPCHPNCT---------------------------------------------QGCNGPTSHDCIYYP---------------------------WTGHSTLPQHARTPLIAAG------------------VIGGLFILVIMALTFAVYVRRKSIKKK----RALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPN---DSKFFQNLLDEED-LEDMMDAEEYLVPQAFNIPPPIYTSRTRIDSNRSEIGHSPPPAYTPMSGNQFVYQDGGFATQQGMPMPYRATTSTIPEAP-VAQGATAEMFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERNPRGELDEEGYMTPMHDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHSASSGPPKAEDEYVNEPLYLNTFAN------------------------------------------------------ALGSAEYMKNSVLS-----------------------------------------------------------VPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTMLPPPPYRHRNTVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15303-1", "uniprot_id": "ERBB4_HUMAN", "id": "Q15303-1", "name": "Receptor tyrosine-protein kinase erbB-4", "aln": "----------------MKPATGLWVWVSLLVAAGTVQPSDSQ---------------------------------------------------------SVCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEH-NRDLSFLRSVREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAIFLNYRKDGNFGLQELGLKNLTEILNGGVYVDQNKFLCYADTIHWQDIVRNPWPSNLTLVSTNGSSGCGRCHKSCTGRCWGPTENHCQTLTRTVCAEQCDG-RCYGPYVSDCCHRECAGGCSGPKDTDCFACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLIFLVTGIHG--DPYN------AIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGG-RVLYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRKAENCTAEGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRICIESCNLYDGEFREFENGSICVECDPQCEKMEDGLLTCHGPGPDNCTKCSHFKDGPNCVEKCP-----------------DGLQG----------------------------------ANSFIFKYADPD--------------RECHPCHPNCT---------------------------------------------QGCNGPTSHDCIYYP---------------------------WTGHSTLPQHARTPLIAAG------------------VIGGLFILVIVGLTFAVYVRRKSIKKK----RALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHGCLLEYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPN---DSKFFQNLLDEED-LEDMMDAEEYLVPQAFNIPPPIYTSRARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVSVPYRAPTSTIPEAP-VAQGATAEIFDDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFAN------------------------------------------------------TLGKAEYLKNNILS-----------------------------------------------------------MPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPIVAENPEYLSEFSLKPGTVLPPPPYRHRNTVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q7Y5-1", "uniprot_id": "A0A8M9Q7Y5_DANRE", "id": "A0A8M9Q7Y5-1", "name": "Receptor protein-tyrosine kinase", "aln": "-----------------MWPVRFLLLFCLVFTFAVLQRSSGQ---------------------------------------------------------SVCPGTDNKLSTLSDLDQQYKTLRKFYENCEVVMGNLEITSIER-NRNLSFLKSIREVTGYVLVALNQFDYLPLENLRIIRGTKLYEGRYSLAIFLNYRRDGYFGLRQLGLRNLTEILNGGVYVDQNKFLCHADTIHWQDIIKNPRSELLVVPSNNSGNTCRRCHRSCNGRCWGPQEDQCQSLTKTVCAEQCDG-RCFGPYVSNCCHRECAGGCFGPKDTDCFACTNFNDSGACVTQCPQPFVYNPTTFQLEHNPNAKYTYGAFCVKKCPHNFVVDHSSCVRACPSNKTEVEENNIKMCIQCTEICPKMCDGIGTGSLQSAQTVDSSNIEKFVNCTKINGNLIFLITGIKG--DMYH------GIRALDPERLNVFRTVREITGYLNIQSWPENMTDLSVFSNLVTIGG-RTLYSGISLLILKQRWITSLQFQSLREISAGNVYMTNNSQLCFYSTVNWTSLFRTSTQKAKIKDNRDPRECSQQRMVCDPLCSVSGCWGPGPNQCLSCKYFSRGRTCVRSCNLYNGDVREFANGSTCVECDSQCEKAEDKSLTCHGPGPDHCVKCLHLKDGPNCVEKCP-----------------DGLQG----------------------------------ANSFIFKYPETN--------------NECHPCHPNCT---------------------------------------------QGCTGPRIQDCIG-------------------------------------ILDRTPLIAAG------------------VIGGMFVVVIVALGFAIFFRRKSIKKK----RALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKILGTGAFGTVYKGIWVPEGETVKIPVAIKILNESTGPKANVEFMDEALIMASMEHPHLVRLLGVCLSPTIQLVTQLMPHGCLLDYVHEHQDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHIKITDFGLARLLETNEKEYSADEGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYDGIPTREIPDILEKGERLPQPPICTIDVYMVMVKCWMIDADSRPRFKELAAEFSRMARDPQRYLVIQGDDRMKLPSPN---HSKFFQSLLDEEE-LDDLMDADEYLVPHSLNAPPTSHIPHPHVDSNQ----------------NQFGYHDGSRCPEDVTRFHEVAAAGNAPSALGSAQRAGLDLVEEQHCNGSLKKQATVHSVEDSSGQRYSADPTVLLGEKTQREDTDEDGYMSPMKDKISTNHLNPVEENPFVTRRKSKDVHALDNPGYHNTPDGKPKCEDEYINEPLYLNTFNNTSDIHQEMLRKNGVSIPAQMTTAGHILQTGKPHHHSHGPHVHFAIPPVQPVHPGPMSQNDHNAHSVQSGHDHAVKSGPSAGQICLVSHQVQQGHPSKSNRSPQQFQLSGGKLPGHPVQPGSQIGTVLVDKMYKNSFDNPEYWQHSLPP-PQISQDSSSAVCNNKFLYKQNGRVQPPAAENPEYLSG--VKPGMVLPPPPYRQRNTVV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P04412-1", "uniprot_id": "EGFR_DROME", "id": "P04412-1", "name": "Epidermal growth factor receptor", "aln": "MLLRRRNGPCPFPLLLLLLAHCICIWPASAARDRYARQNNRQRHQDIDRDRDRDRFLYRSSSAQNRQRGGANFALGLGANGVTIPTSLEDKNKNEFVKGKICIGTKSRLSVPSNKEHHYRNLRDRYTNCTYVDGNLKLTWLPNENLDLSFLDNIREVTGYILISHVDVKKVVFPKLQIIRGRTLFSLSVEEEKYALFVTYS--KMYTLEIPDLRDVLNGQVGFHNNYNLCHMRTIQWSEIVSNGTDAYYNYDFTAPERECPKCHESCTHGCWGEGPKNCQKFSKLTCSPQCAGGRCYGPKPRECCHLFCAGGCTGPTQKDCIACKNFFDEAVSKEECPPMRKYNPTTYVLETNPEGKYAYGATCVKECPGHLLRDNGACVRSCPQDKMDKGGE----CVPCNGPCPKTCP--------GVTVLHAGNIDSFRNCTVIDGNIRILDQTFSGFQDVYANYTMGPRYIPLDPERREVFSTVKEITGYLNIEGTHPQFRNLSYFRNLETIHGRQLMESMFAALAIVKSSLYSLEMRNLKQISSGSVVIQHNRDLCYVSNIRWPAIQKEPEQKVWVNENLRADLCEKNGTICSDQCNEDGCWGAGTDQCLTCKNFNFNGTCIADCGYIS-NAYKFDN-RTCKICHPECR-------TCNGAGADHCQECVHVRDGQHCVSECPKNKYNDRGVCRECHATCDGCTGPKDTIGIGACTTCNLAIINNDATVKRCLLKDDKCPDGYFWEYVHPQEQGSLKPLAGRAVCRKCHPLCELCTNYGYHEQVCSKCTHYKRREQCETECPADHYTDEEQRECFQRHPECNGCTGPGADDCKSCRNFKLFDANETGPYVNSTMFNCTSKCPLEMRHVNYQYTAIGPYCAASPPRSSKITANLDVNMIFIITGAVLVPTICILCVVTYICRQKQKAKKETVKMTMALSGCEDSEPLRPSNIGANLCKLRIVKDAELRKGGVLGMGAFGRVYKGVWVPEGENVKIPVAIKELLKSTGAESSEEFLREAYIMASEEHVNLLKLLAVCMSSQMMLITQLMPLGCLLDYVRNNRDKIGSKALLNWSTQIAKGMSYLEEKRLVHRDLAARNVLVQTPSLVKITDFGLAKLLSSDSNEYKAAGGKMPIKWLALECIRNRVFTSKSDVWAFGVTIWELLTFGQRPHENIPAKDIPDLIEVGLKLEQPEICSLDIYCTLLSCWHLDAAMRPTFKQLTTVFAEFARDPGRYLAIPGDKFTRLPAYTSQDEKDLIRKLAPTTDGSEAIAKPDDYLQPKAAPGPS-----------------------------------------------HRTDCTDEMPKLN------------------RYCKDPSNKNSSTGDDERDSSAREVGVGNLRLDLPVDEDDYLMPTCQPGPNNNNNMNNPNQNNMAAVGVAAGYMDLIGVPVSVDNP-----EYLLNAQTLGVGES---------------------------------------------------------------------------------------------------------------------------------PIPTQTIGIPVMGGPGTMEVKVPMPGSEPTSSDHEYYNDTQRELQPLHRN---------------------RNTETRV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . : . * .:* **..:** *: :::*: **. * ** * ***::* : . * :**** .:******:*:: :. : : :*:**** .*:. : : . : * : :* ::*** * ..:* **: **:*.:*: * . * :**.**. *** .:**.::: .*: ** * **:** :*** ***** **.:.**:** ** *.... :** *****: ** * :.**:*** ***:** ::: * .:***:**..* : : * *. *** * .. .:.:.**:.* *** *:**: :* : * * * .:***: :** **:****:***: :: ::* * ** ** * : : * :: * : : : **:::.*::**:*.: : .* :**: .:.*.:: *: :.:* . * : :*. *. .****.*.:***:*: *. . *: .*. . : :* * * *..:*. **:*.*.*:* :* *.:** :**.:** * * .:.::::* . : .:*** ** :**.** .** * **. : *.::: .* * .. :. *:. * * : : * *** **. ..* .:***:*::**:: :** **** ****:******.******** * ::**.::. **: ** **** :* :*::**.**:*. : *:***** ****:**::::*:***: ****..****** ****:**************::*. :********:**. :.:**.* *******:*****: * ** :****::*******:*** :*::.**:::***::* * :* ** **::*:* .::.** :** ** **:*:: *:.:**** ***.* **. :**: . ...:::.* : : : ..::** *:: *. :. *. * : . .. :* *: * : **:.*: * : : * : * . :* : .. **: :. *.. . .:::. * . . . :: . : .::* : *: :* *", "identical_positions": 427, "similar_positions": 353, "identity": "25.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-77", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H4D0-1", "uniprot_id": "CSTN2_HUMAN", "id": "Q9H4D0-1", "name": "Calsyntenin-2", "aln": "MLPGRLCWVPLLLALGVGSG--SGGGGDSRQRRLLAAKVNKHKPWIETSYHGVITENNDTVILDPPLVALDKDAPVPFAGEICAFKIHGQELPFEAVVLNKTSGEGRLRAKSPIDCELQKEYTFIIQAYDCGAGPHETAWKKSHKAVVHIQVKDVNEFAPTFKEPAYKAVVTEGKIYDSILQVEAIDEDCSPQYSQICNYEIVTTDVPFAIDRNGNIRNTEKLSYDKQHQYEILVTAYDCGQKPAAQDTLVQVDVKPVCKPGWQDWTKRIEYQPGSGSMPLFPSIHLETCDGAVSSLQIVTELQTNYIGKGCDRETYSEKSLQKLCGASSGIIDLLPSPSAATNWTAGLLVDS---SEMIFKFDGRQGAKVPDGIVPKNLTDQFTITMWMKHGPSPGVRAEKETILCNSDKTEMNRHHYALYVHNCRLVFLLRKDFDQADTFRPAEFHWKLDQICDKEWHYYVINVEFPVVTLYMDGATYEPYLVTNDWPIHPSHIAMQLTVGACWQGGEVTKPQFAQFFHGSLASLTIRPGKMESQKVISCLQACKEGLDINSLESLGQGIKYHFNPSQSILVMEGDDIGNINRALQKVSYINSRQFPTAGVRRLKVSSKVQCFGEDVCISIPEVDAYVMVLQAIEPRITLRGTDHFWRPAAQFESARGVTLFPDIKIVSTFAKTEAPGDVKTT--DPKSEVLEEMLHNLDFCDILVIGGDLDPRQECLELNHSELHQRHLDATNSTAGYSIYGVGSMSRYEQVLHHIRYRNWRPASLEARRFRIKCSELNGRYTSNEFNLEVSILHEDQVSDKEHVNHLIVQPPFLQSVHHPESRSSIQHSSVVPSIATVVIIISVCMLVFVVAMGVYRVRIAHQHFIQETEAAKESEMDWDDSALTITVNPMEKHEGPGHGEDE-TEGEEEEEAEEEMSSSSGSDDSEEEEEEEGMGRGRHGQNGAR---QAQLEWDDSTLPY---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9ER65-1", "uniprot_id": "CSTN2_MOUSE", "id": "Q9ER65-1", "name": "Calsyntenin-2", "aln": "MLPGRLCLVPLLLALGVGSGGGSGDGGDSRRRRLLVAKVNKHKPWIETSYHGVITENNDTVILDPPLVALDKDAPVPFAGEICAFKIHGQELPFEAVVLNKTSGEGRLRAKSPIDCELQKEYTFIIQAYDCGAGPREAAWKKSHKAVVHIQVKDVNEFAPTFKEPAYKAIVTEGKIYDSILQVEAIDEDCSPQYSQICNYEIVTTDVPFAIDRNGNIRNTEKLSYDKQHQYEILVTAYDCGQKPAAQDTLVQVDVKPVCKPGWQDWTKRIEYQPGSGSMPLFPSIHLETCDGAVSSLQVTAELQTNYIGKGCDRETYSEKSLQKLCGASSGIIDLLPSPSAATNWTAGLLVDS---SEMIFKFDGRQGAKIPDGIVPKNLTDQFTITMWMKHGPSPGVRAEKETILCNSDKTEMNRHHYALYVHNCRLVFLLRKDFDQADTFRPAEFHWKLDQICDKEWHYYVINVEFPVVTLYMDGATYEPYLVTNDWPIHPSHIAMQLTVGACWQGGEVAKPRFAQFFHGSLASLTIRPGKMESQKVISCLQACKEGLDINSLESLGRGIKYHFNPSQSILVMEGDDIGNINRALQKVSYINSRQFPTAGVRRLRLSSKVQCFGEDVCISIPDVDAYIMVLQAIEPQITLQGTERFWRPAAQFESARGVTLFPDIKIVSTFAKTEASGDMRATGTAPKSAVLEEMLHNLDFCDILVLGGDLDPRQECLELNHSELHQRHLDATNSTAGYSIYGVGSMNRYEQVLHHLRYRNWHPTSLETRRFRIKCSELNGRYTSNEFNLEVSVLHEVRVSDKEHVNHLIVQPPFLQSVHHPETRSSIQRSSVVPSIATVVIIISVCMLVFVVAMGVYRVRIAHQHFIQETEAAKEAEMDWDDSALTITVNPMEKHEGPGNGEDETTEVEEEEEAEEGSSSSSSGSDDSEEEEEEGMGRVRHGQSGTSSQSPERSTWNTAGVINIWK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "R4GEC6-1", "uniprot_id": "R4GEC6_DANRE", "id": "R4GEC6-1", "name": "Calsyntenin-2", "aln": "-MKRKLMLMLLALGL-------SCVR---------AHRVNKHKPWIETSYHGVITENTDEVLLDPPLVALDKDAPVPYAGEICGFHVQGLSAPFEAVLLNGTSGEGRLRARGPIDCERHREFSFIIQAHDCGTGPQGHGQKRSHKAAVRVQVGDVNEFSPVFGQLEYHGSVTEGKVYDSILQVQASDQDCSPQYSQICNYQITSPDTAFAVDRNGNIRNTESLSFEKKSHYKIRVTALDCGQKRAMQEAIVHIHVKPICKPGWQGWRKLVDYEPGAGSKLLFPKMHLETCEGSVSWIRTTVELETSGVGRGCD----SERSLQKLCGSSSGSTALLPATGGVCNWTVTLVRDSGRDSDLAYRFDGHQAAKIPDWVVPQNLTDQFTITTWMKHGPSPGQRAEKETLLCNSDKTEMNRHHYSLYVHNCRLVFLLRTDYTQTDSFRPAEFHWKLEQICDKEWHYYVLSVDFPVVTLYVDGVTYEPYLVTDDWPIHSSQIDVQLTVGACWQGGEVSKAKFSQYFRGSLSGLTIRPGKIESQKIISCLQACKEGLDITSLENLGQRIKFHLNPAQSVLVMEAEDLEQMNGALRKVSYINSRQFPTMGSRHLRISTAVQCFGEDVCISVPDIEVVVMVMQPSEARITITGAEHLTIPA--YDLALGLSLFRDLHIISTVTKRDKVTNMDHR------SSAKETAHNLDYCDILVLGEELRAGLESLELHHSALLGKHLEYANSSTGMSIYGVDSISHYTEVIRQVRYQSRR-AVDSVRTFRLTCSELNGRYTSDQYTLQVNILHSEEAR--EHVNHLMTPPKSMQITHRTVMESNNYFNLVVPAVSTSVVVVCIAALL-VVLLGVYQLNQTQNKDSIQTHTLAEEQVDCEGSSLSITVNPLQNCQ-----ELQSAEVTEEEEDEEDCAISSTESDSDEEETDTPFTHR-----------QTKQQWGKATLHC---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* : * *.* * . :*******************.* *:***************:*****.*:::* . *****:** *********:.***** ::*::*****:***:**: . *:****.*::** *****:*.* : *:. *****:*******:* *:************:*.:.*..**:**********.**::*: :*:* *** ***** * *:::*::.***:******.* * ::*:**:** ***.:*****:*:** :: ..**:*. :*:*** **:*******:*** ***:.... ***. *: ** *:: ::***:*.**:** :**:********* ********* ******:**************:*************.*: *:*:**********:***********:.*:*******:**.********:*****.*:* :*************:*.:*:*:*:***:.*******:****:*************.***.**: **:*:**:**:****.:*: ::* **:************ * *:*::*: ***********:*:::. :**:*. *.:**: *:::: ** :: * *::** *::*:**.:* : :: :* ****:*****:* :* . *.***:** * :**: :**::* *****.*:.:* :*::::**:. : : ..* **:.**********:::.*:*.:**. .. ******:. * :* .*:. .*. . ***:::* *:::.:. *: ** :***::. :::: :*.: * ::* :.*:*:*****::: : * : :* **** ** : ** .*..*** : : : : *. : : ", "identical_positions": 525, "similar_positions": 254, "identity": "54.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-84", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ULK0-1", "uniprot_id": "GRID1_HUMAN", "id": "Q9ULK0-1", "name": "Glutamate receptor ionotropic, delta-1", "aln": "MEALTLWLLPWICQCVSVRADSIIHIGAIFEENAAKDDRVFQLAVSDLSLNDDILQSEKITYSIKVIEANNPFQAVQEACDLMTQGILALVTSTGCASANALQSLTDAMHIPHLFVQRNPGGSPRTACHLNPSPDGEAYTLASRPPVRLNDVMLRLVTELRWQKFVMFYDSEYDIRGLQSFLDQASRLGLDVSLQKVDKNISHVFTSLFTTMKTEELNRYRDTLRRAILLLSPQGAHSFINEAVETNLASKDSHWVFVNEEISDPEILDLVHSALGRMTVVRQIFPSAKDN-QKCTRNNHRISSLLCDPQEGYLQMLQISNLYLYDSVLMLANAFHRKLEDRKWHSMASLNCIRKSTKPWNGGRSMLDTIKKGHITGLTGVMEFREDSSNPYVQFEILGTTYSETFGKDMRKLATWDSEKGLNGSLQERPMGSRLQGLTLKVVTVLEEPFVMVAENILGQPKRYKGFSIDVLDALAKALGFKYEIYQAPDGRYGHQLHNTSWNGMIGELISKRADLAISAITITPERESVVDFSKRYMDYSVGILIKKPEEKISIFSLFAPFDFAVWACIAAAIPVVGVLIFVLNRIQAVRAQS--AAQPRPSASATLHSAIWIVYGAFVQQGGESSVNSMAMRIVMGSWWLFTLIVCSSYTANLAAFLTVSRMDNPIRTFQDLSKQVEMSYGTVRDSAVYEYFRAKGTNPLEQDSTFAELWRTISKNGGADNCVSSPSEGIRKAKKGNYAFLWDVAVVEYAALTDDDCSVTVIGNSISSKGYGIALQHGSPYRDLFSQRILELQDTGDLDVLKQKWWPHMGRCDLTSHASAQADGKSLKLHSFAGVFCILAIGLLLACLVAALELWWNSNRCHQETPKED-KEVNLEQVH----------------------RRMNSLMDEDIAHKQISPASIELSALEMG-GLAPTQTLEPTREYQNTQLSVSTFLPEQSSHGTSRTLSSGPSSNLPLPLSSS---ATMPSMQCKHRSPNGG--------LFRQSPVKTPIP-MSFQPVPGGVLPEALDTSHGTSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61627-1", "uniprot_id": "GRID1_MOUSE", "id": "Q61627-1", "name": "Glutamate receptor ionotropic, delta-1", "aln": "MEALTLWLLPWICQCVTVRADSIIHIGAIFEENAAKDDRVFQLAVSDLSLNDDILQSEKITYSIKVIEANNPFQAVQEACDLMTQGILALVTSTGCASANALQSLTDAMHIPHLFVQRNPGGSPRTACHLNPSPDGEAYTLASRPPVRLNDVMLRLVTELRWQKFVMFYDSEYDIRGLQSFLDQASRLGLDVSLQKVDKNISHVFTSLFTTMKTEELNRYRDTLRRAILLLSPQGAHSFINEAVETNLASKDSHWVFVNEEISDPEILDLVHSALGRMTVVRQIFPSAKDN-QKCMRNNHRISSLLCDPQEGYLQMLQISNLYLYDSVLMLANAFHRKLEDRKWHSMASLNCIRKSTKPWNGGRSMLDTIKKGHITGLTGVMEFREDSSNPYVQFEILGTTYSETFGKDMRKLATWDSEKGLNGSLQERPMGSRLQGLTLKVVTVLEEPFVMVAENILGQPKRYKGFSIDVLDALAKALGFKYEIYQAPDGRYGHQLHNTSWNGMIGELISKRADLAISAITITPERESVVDFSKRYMDYSVGILIKKPEEKISIFSLFAPFDFAVWACIAAAIPVVGVLIFVLNRIQAVRSQS--ATQPRPSASATLHSAIWIVYGAFVQQGGESSVNSVAMRIVMGSWWLFTLIVCSSYTANLAAFLTVSRMDNPIRTFQDLSKQLEMSYGTVRDSAVYEYFRAKGTNPLEQDSTFAELWRTISKNGGADNCVSNPSEGIRKAKKGNYAFLWDVAVVEYAALTDDDCSVTVIGNSISSKGYGIALQHGSPYRDLFSQRILELQDTGDLDVLKQKWWPHTGRCDLTSHSSTQTEGKSLKLHSFAGVFCILAIGLLLACLVAALELWWNSNRCHQETPKED-KEVNLEQVH----------------------RRINSLMDEDIAHKQISPASIELSALEMG-GLAPSQALEPTREYQNTQLSVSTFLPEQSSHGTSRTLSSGPSSNLPLPLSSS---ATMPSIQCKHRSPNGG--------LFRQSPVKTPIP-MSFQPVPGGVLPEALDTSHGTSI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "R4GDN8-1", "uniprot_id": "R4GDN8_DANRE", "id": "R4GDN8-1", "name": "Glutamate receptor", "aln": "MELLIICLSFGILQCSSAGADSIIHIGAIFEENAARDDEVFQLAISDLSLNDDILQSEKITHSIKYIEPNNPFQAVQEACELMTQGILALVTSTGCASASALQSLTDAMHIPHLYVQRNAEGSPRTACQLNPSPDGERYTLAARPPVRLGDVMLTLVGELRWQKFIVFYDSDYDIRGLQVFLDQTSRQGLDVSLQRVDRNISGVFSSLFTSMRTEELNRYRDTLRRAILLLSPRGAQVFIHQAVETNLASKDSHWVFVNEEISDTEILELAHSSLGRMTVVRQIFPLWRDSSVSCMRNSHRISSLLCDPQEGYLQSLEVSNLYLYDSVLMLANAFYRKLEDRKWHSMASLNCIRKSTKPWNGGWSMLETIQKGRITGLTGIMDFMENGSNSHVQFEILGTSFSETFGKDIKRLATWDSVHGLNGSLKESRIENGMQGVTVKVVTLLEDPFVMVAENILGQPKRYKGFSIDVLEALAKILGFKYDIYQVADSKYGSQLSNGSWNGMIGELINKRADLAVSAITITPERENVVDFSKRYMDYSVGILHRKPEEKINIFSLFAPFDLAVWACIAAAIPVVGVLIFLLTRMQMLRSQNPPGAHHASSMSNSLHSAIWIVYGAFVQQGGDSVVGSVALRIVMGSWWLFTLIVCSSYTANLAAFLTVSRMDNTIRTFQDLARQMDFAYGTVRDSAVYDYFKAKGTNPLEQDSTYAELWRTISKNNGQDFSVSSPSEGIRKAKKGPYAFLWDMAVVEYAALTDDDCTITVSGNSMSSKGYGIAMQHGSPYRDLISQKILELQEKGDLDVLKQKWWPRTGRCDLNSHSNAQPDGRSLKLHSFAGVFCILAAGLLLACLVAALEMWWNSNRCRQEQPKEVTKDYRLARVSGPLTYNDIATASSEGSKDIWTDRERDWDEAEAIDTGQGGEPGTGASAFEQPYGRGHGTQADPRTIYRDLCPGHRQHAAQPAAGGCARLPGHGPVCEHLPPGASSWGGSDTDPGSWQHPAPSSQQLHHPLHPMQTQGSQRGPVPTESRQDTHANVLPISTRRTHPRSY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * : * * ** :. ****************:**.*****:****************:*** **.***********:******************.**************:****. *******:******** ****:******.**** ** *******::****:******* ****:** *******:**:*** **:****:*:********************:**: **::**********************.***:*.**:************ :*. .* **.**************** *::****************:*************************** ***:**:**:******:*:* *:.**.:********::*******:::****** :******:* : . :**:*:****:**:************************:**** *****:***..*.:** ** * **********.******:**********.**************** :******.*********:******************:*.*:* :*:*. .:: .* * :*****************:* *.*:*:*********************************.*******::*::::**********:**:************:**********.* * .**.*********** ******:*************::** ***:********:*********:**:*****:.************: *****.**:.:*.:*:*************** ************:*******:** *** *: .* :* *. : * * * . .. **:* * . :* *:: . . .: :: * :* . ** .: * :** : . . :* :*.. : *.. : *:* * * . ..*** : :* * ", "identical_positions": 730, "similar_positions": 162, "identity": "69.66%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-93", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M2Y4-1", "uniprot_id": "F1M2Y4_RAT", "id": "F1M2Y4-1", "name": "Equilibrative nucleoside transporter 4", "aln": "MGSIGSQRLKEPCVAATSGQSVVT--SFDNFQLETTIEGAQDPGIRVRGVPPFTDSAVDEPVPDDRYHAIYFAMLLAGVGFLLPYNSFITDVDYLHHKYPGTSIVFDMSLTYILVALAAVLLNNVVVERLNLHTRITTASLLPAGYLLALGPLLFISIFDVWLQLFSHDQAYAINLAAVGTVAFGCTVQQSSFYGYTGLLPKRYTQGVMTGESTAGVMISLSRILTKLLLPDERASTIIFFLVSAGLELLCFLLHLLVRRSRFVLYYTTRP-----RDSRPVRAG------YRVHHDVASG--------------------DIHFEHQTPALSSSRSPKDSPAHEVTHSN----SGVYMRFDVPRPRVKR-----SWPTFRALLLHRYVVARVIWADMLSIAVTYFITLCLFPGLESEIRHCVLGEWLPILVMAVFNLSDFVGKILAALPVDWRGTHLLACSCLRVVFIPLFILCVYPTGMPALRHPAWPCVFSLLMGISNGYFGSVPMILAAGKVSPKQRELAGNTMTVSYMSGLTLGSAVAYCTYSLT-------------------------------------------------------------------------RDAHS--SCFQTAT---ANDSILVGP----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R139-1", "uniprot_id": "S29A4_MOUSE", "id": "Q8R139-1", "name": "Equilibrative nucleoside transporter 4", "aln": "MGSIGSQRLKEPCVAATSDQSVVTSFSFDNFQLETTAEGAQDPGIRVRGVPTFTDSAVEEPVPDDRYHAIYFAMLLAGVGFLLPYNSFITDVDYLHHKYPGTSIVFDMSLTYILVALAAVLLNNVVVERLNLHTRITTG------YLLALGPLLFISICDVWLQLFSHDQAYAINLAAVGTVAFGCTVQQSSFYGYTGLLPKRYTQGVMTGESTAGVMISLSRILTKLLLPDERASTIIFFLVSAGLELLCFLLHLLVRRSRFVLYYTTRP-----RDSRPVQAG------YRVHHDVASG--------------------DIHFEHQTPALSSSRSPKESPAHEVTHSN----SGVYMRFDVPRPRVKR-----SWPTFRALLLHRYVVARVIWADMLSIAVTYFITLCLFPGLESEIRHCVLGEWLPILVMAVFNLSDFVGKILAALPVEWRGTHLLACSCLRVVFIPLFILCVYPSGMPALRHPAWPCVFSLLMGISNGYFGSVPMILAAGKVSPKQRELAGNTMTVSYMSGLTLGSAVAYCTYSLT-------------------------------------------------------------------------RDAHG--SCFQTATAAAANDSIPVGP----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7RTT9-1", "uniprot_id": "S29A4_HUMAN", "id": "Q7RTT9-1", "name": "Equilibrative nucleoside transporter 4", "aln": "MGSVGSQRLEEPSVAGTPDPGVVMSFTFDSHQLEEAAEAAQGQGLRARGVPAFTDTTLDEPVPDDRYHAIYFAMLLAGVGFLLPYNSFITDVDYLHHKYPGTSIVFDMSLTYILVALAAVLLNNVLVERLTLHTRITAG------YLLALGPLLFISICDVWLQLFSRDQAYAINLAAVGTVAFGCTVQQSSFYGYTGMLPKRYTQGVMTGESTAGVMISLSRILTKLLLPDERASTLIFFLVSVALELLCFLLHLLVRRSRFVLFYTTRP-----RDSHRGRPGLGRGYGYRVHHDVVAG--------------------DVHFEHPAPALAPNESPKDSPAHEVTGS-----GGAYMRFDVPRPRVQR-----SWPTFRALLLHRYVVARVIWADMLSIAVTYFITLCLFPGLESEIRHCILGEWLPILIMAVFNLSDFVGKILAALPVDWRGTHLLACSCLRVVFIPLFILCVYPSGMPALRHPAWPCIFSLLMGISNGYFGSVPMILAAGKVSPKQRELAGNTMTVSYMSGLTLGSAVAYCTYSLT-------------------------------------------------------------------------RDAHG--SCLHAST---ANGSILAGL----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PWY6-1", "uniprot_id": "A0A8M9PWY6_DANRE", "id": "A0A8M9PWY6-1", "name": "", "aln": "MYSEEWSRNRQ-----GREKTVITNFSFSQLPEEEKTGRRK----------PHSAHDSDESIPDDRYHSIYFAMLLAGVGFLLPYNSFITDVDYLHRKFKGTSIVFDMSLTYILVALSAVIVNNALVERLSLHTRICVG------YLFALGPLVCVSVFDVWLELFNTQQSYAVTLAAVAIVAFGCTVQQSSFYGYTGMLPKRYTQGVMTGESTAGVIVSLSRIFTKLLVEDEKNNTIIFFLFSVSMETLCFLLHVVVRRTHFVRYHTSRA-----RQSHSWLKG----QINNVTTQKHSGY-------------------QIHYDSSAEEEDGMASSMVDDADAVNLGNGSHGDGIYVRFDVPKPEAKR-----SWISVKELLGRRCAVARVIWPYMLSILVTYFITLCLFPGLESELHNDTLGEWLPILTMALFNMADFVGKILAACPYEWGGVQLLVCSCLRVLFLPLFVMCVSPVQRPLLAHPAWPCGLSVMLGISNGYLGSVPMIQAAGKVPLQQREVAGNTMTVSYMAGLMLGSAVSYSTYSLT-------------------------------------------------------------------------SQAHSSHTTLKLNSTLTLHNYMPGH-----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VU20-1", "uniprot_id": "Q9VU20_DROME", "id": "Q9VU20-1", "name": "", "aln": "MDVGGQETTYEPLDGRGSGRSRSSHSTTGSGLRRPGS---------------MDSPEFDNRAPKDQRHSVYLALLAAGIGFVLPYNSFIIAADYWQARFPGRPVALDMSMTYIFVAFGTVLMNNIVLSVAPFQSRVLFG------YMISFTTLIFVAVCEVAWHMFATNTAYLVNMSAVALTAIGCTVQQSSFYGFASMLPKQYTQAVMAGESIAGFLVSSNRVVTKLLINNDRVSTVIFFLTSTLYILFSYLLHVATINSPFVRFHVEACSKIVLRPDEQEIDGVPSSTRYGVLSMDGTHTTTTSVGPPGTGNTLSFSNPVYELSNPTAGESSIEALGQLPELPATPPAQEPTTPTTVAFKVEHVITPRRCRPSKLGDIREGFVTRWRVAQVIYPHMVCIALAYCVTLSLYPGIEVEVQSCALRSWMPVLLMFCFNTSDVVGKILAASPYPWSRRQLILLSGLRIVLVPLLLLCCAPRQRPVISGETAPFVFTIALGITNGLAGSLPMMLAPAKVPGTLKEVTGNIMTLSYNVGLTVGSLIGYVFESMLGPQLVNPCPTYPYVPASMLEQFHGHGHGHGHLPHPLPLTSTSTMSPPTTGATTLAPLLLNTTLATLSSSSSTTSTASPALATVITTTALALASTVASGSAEVINATISSILSTVSSSVGDISDEMTTDPQTPDALLENI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : : .. . :: *.*: *::*:*:* **:**:******* .** : :: * .:.:***:***:**:.:*::** ::. :::*: . *:::: .*: ::: :* .:* : :* :.::**. .*:***********::.:***:***.**:*** **.::* .*:.****: ::: .*:**** *. :.:***: . .: ** ::. * .. * * : . . : : .. : *.* : . * . .: : * **:**:. *:.* ::* :**.*:**:* *:: * .*:*:* * ** :*.******* * * :*: * **::::**:::* * * : : * ::: :**:** **:**: *..**. :*::** **:** ** :** :.* *: * : . : . : ", "identical_positions": 155, "similar_positions": 159, "identity": "22.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-95", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8QZR5-1", "uniprot_id": "ALAT1_MOUSE", "id": "Q8QZR5-1", "name": "Alanine aminotransferase 1", "aln": "--------------------------------------------------------------------MASQRNDRIQASRNGLK----------------------GKVLTLDTMNPCVRRVEYAVRGPIVQRALELEQELRQG-VKKPFTEVIRANIGDAQAMGQRPITFFRQVLALCVYPNLLSSPD--------FPEDAKRRAERILQACGGHSLGAYSISSGIQPIREDVAQYIERRDGGIPADPNNIFLSTGASDAIVTMLKLLVAGEGRARTGVLIPIPQYPLYSAALAELDAVQVDYYLDEERAWALDIAELRRALCQARD-RCCPRVLCVINPGNPTGQVQTRECIEAVIRFAFEEGLFLMADEVYQDNVYAEGSQFHSFKKVLTEMG---PPYATQQELASFHSVSKGYMGECGFRGGYVEVVNMDAEVQKQMAKLMSVRLCPPVPGQALMGMVVSPPTPSEPSFKQFQAERQEVLAELAAKAKLTEQVFNEAPGIRCNPVQGAMYSFPQIQLPLKAVQRAQDLGLAPDMFFCLCLLEETGICVVPGSGFGQQEGTYHFRMTILPPMEKLRVLLEKLRHFHAKFTHEYS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25409-1", "uniprot_id": "ALAT1_RAT", "id": "P25409-1", "name": "Alanine aminotransferase 1", "aln": "--------------------------------------------------------------------MASRVNDQSQASRNGLK----------------------GKVLTLDTMNPCVRRVEYAVRGPIVQRALELEQELRQG-VKKPFTEVIRANIGDAQAMGQRPITFFRQVLALCVYPNLLSSPD--------FPEDAKRRAERILQACGGHSLGAYSISSGIQPIREDVAQYIERRDGGIPADPNNIFLSTGASDAIVTMLKLLVSGEGRARTGVLIPIPQYPLYSAALAELDAVQVDYYLDEERAWALDIAELRRALCQARD-RCCPRVLCVINPGNPTGQVQTRECIEAVIRFAFKEGLFLMADEVYQDNVYAEGSQFHSFKKVLMEMG---PPYSTQQELASFHSVSKGYMGECGFRGGYVEVVNMDAEVQKQMGKLMSVRLCPPVPGQALMDMVVSPPTPSEPSFKQFQAERQEVLAELAAKAKLTEQVFNEAPGIRCNPVQGAMYSFPQVQLPLKAVQRAQELGLAPDMFFCLCLLEETGICVVPGSGFGQQEGTYHFRMTILPPMEKLRLLLEKLSHFHAKFTHEYS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P24298-1", "uniprot_id": "ALAT1_HUMAN", "id": "P24298-1", "name": "Alanine aminotransferase 1", "aln": "--------------------------------------------------------------------MASSTGDRSQAVRHGLR----------------------AKVLTLDGMNPRVRRVEYAVRGPIVQRALELEQELRQG-VKKPFTEVIRANIGDAQAMGQRPITFLRQVLALCVNPDLLSSPN--------FPDDAKKRAERILQACGGHSLGAYSVSSGIQLIREDVARYIERRDGGIPADPNNVFLSTGASDAIVTVLKLLVAGEGHTRTGVLIPIPQYPLYSATLAELGAVQVDYYLDEERAWALDVAELHRALGQARD-HCRPRALCVINPGNPTGQVQTRECIEAVIRFAFEERLFLLADEVYQDNVYAAGSQFHSFKKVLMEMG---PPYAGQQELASFHSTSKGYMGECGFRGGYVEVVNMDAAVQQQMLKLMSVRLCPPVPGQALLDLVVSPPAPTDPSFAQFQAEKQAVLAELAAKAKLTEQVFNEAPGISCNPVQGAMYSFPRVQLPPRAVERAQELGLAPDMFFCLRLLEETGICVVPGSGFGQREGTYHFRMTILPPLEKLRLLLEKLSRFHAKFTLEYS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IKG8-1", "uniprot_id": "A0A0R4IKG8_DANRE", "id": "A0A0R4IKG8-1", "name": "alanine transaminase", "aln": "----------------------------------------------------------------------------MTENGCEYH----------------------ERVLTVDTMNPNIKRLEYAVRGPIVQRAVQIDKELKMG-IKKPFTEVIKANIGDCHAMGQKPITFFRQVLALCSYPDLLEDNK--------FPEDAKSRAQRILKACGGGSLGAYSTSQGIEMIRQDVARYIERRDGGIACDPDNIYLSTGASDAIVTMLKLMVSGEGASRTGVMISIPQYPLYSAALAELGAVQINYYLDEDNCWSLDINELRRALQEAKK-HCRPRALCIINPGNPTGQVQSRQCIEEVIRFAADENLFLMSDEVYQDNVYADGCKFHSFKKVLFEMG---PQYSSKVELASFHSTSKCYMGECGFRGGYMEVVNLDPEVKVQLTKLVSVRLCPPVPGQALLDVVVNPPQPDEPSYDTFIKERSDTLAALAEKASMTQDILNQVPGIKCNPVQGAMYTFPRIHLPPKAILKAKENGQSPDMFYCMKLLEETGICLVPGSGFGQRDGTYHFRMTILPLKDKLKVVLAKIKDFHQIFTEQYS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYD9-1", "uniprot_id": "Q9VYD9_DROME", "id": "Q9VYD9-1", "name": "alanine transaminase", "aln": "----------MFKNRKIMSRMLIKPAAATVSAALQQHQRQQQQYVIRRWKSFLHNNSNNANRRAAKSTATATVTAAATSQRHGTSGDFIQPLDVRRSFSTSHKMPSSSKALTLDNINPNFIAMEYAVRGPLVIRAGEIEKELEKG-VKKPFDQVIRANIGDCHAMGQQPLTFLRQLLALTFETRLLDSPD--------YPEDVKKRACAILNGCQGQSVGSYTDSAGLEVVRRQVAQYIEKRDGGIASNWQDIYLTGGASPGIKSILSMINAEVGCKAPGVMVPIPQYPLYSATISEYGMTKVDYYLEEETGWSLDRKELQRSYDEAKK-VCNPRALVVINPGNPTGQVLTRENIEEIIKFAHDNKVLVLADEVYQDNVYDKNSKFWSFKKVAYEMG---DPYRN-LEMVSFLSTSKGYLGECGIRGGYMEVLNLDPKVKAMLTKSITAALCSTTAGQVAVSALVNPPQPGEPSYDLYKKERDGILAALKERAELVHKALNSFEGYKVNPVQGAMYVFPQIEIPPKAIEAAKAKGMAPDVFYAFELLETSGICIVPGSGFGQKPGTWHFRSTILPQTDKLKLMMEKFRVFHAEFMKKYK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P52893-1", "uniprot_id": "ALAT1_YEAST", "id": "P52893-1", "name": "Alanine aminotransferase, mitochondrial", "aln": "MLSLSAKNHFTVSNSITHVIKSYHIRTLTSSAEKMPHITTPFSTSASSTKLKAFRKVRPVLQRHSSSWIVAQNHRRSLSGQSSLNDLRHLNRFPHHTLKTSNNEFYPAEQLTLEDVNENVLKAKYAVRGAIPMRAEELKAQLEKDPQSLPFDRIINANIGNPQQLQQKPLTYYRQVLSLLQYPELLNQNEQQLVDSKLFKLDAIKRAKSLMEDIGG-SVGAYSSSQGVEGIRKSVAEFITKRDEGEISYPEDIFLTAGASAAVNYLLSIFCRG---PETGVLIPIPQYPLYTATLALNNSQALPYYLDENSGWSTNPEEIETVVKEAIQNEIKPTVLVVINPGNPTGAVLSPESIAQIFEVAAKYGTVVIADEVYQENIFP-GTKFHSMKKILRHLQREHPGKFDNVQLASLHSTSKGVSGECGQRGGYMELTGFSHEMRQVILKLASISLCPVVTGQALVDLMVRPPVEGEESFESDQAERNSIHEKLITRAMTLYETFNSLEGIECQKPQGAMYLFPKIDLPFKAVQEARHLELTPDEFYCKKLLESTGICTVPGSGFGQEPGTYHLRTTFLAPGLEW---IKKWESFHKEFFDQYRD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P52892-1", "uniprot_id": "ALAT2_YEAST", "id": "P52892-1", "name": "Inactive alanine aminotransferase", "aln": "---------------------------------------------------------------------MTMTHQQDLKGVFTAKDL----------------DFKPAGKITKKDLNTGVTKAEYAVRGAIPTRADELKEELKKNPEVLPFDDIINANIGNPQQLDQKPLTFTRQVLAILEYPEILRVGHNELASLNLFSRDALERAERLLNDIGG-SIGAYSHSQGVPGIRQTVADFITRRDGGEPATPEDIYLTTGASSAATSLLSLLCKD---SQTGLLIPIPQYPLYTASASLFNAQVLPYYLDEESNWSTNSDEIEKVVQDALKKQIRPSVLIVINPGNPTGAVLSEETIARICLIAAKYGITIISDEVYQENIFN-DVKFHSMKKVLRKLQHLYPGKFDNVQLASLHSISKGFMDECGQRGGYMEIIGFSQEIRDALFKLMSISICSVVTGQAVVDLMVKPPQPGDESYEQDHDERLKIFHEMRTRANLLYETFKELEGIECQKPQGAMYLFPRLVLPKKALCESERLGIEPDEFYCTSLLESTGICTVPGSGFGQRPGTYHVRTTFLAPGTKW---IQDWKEFHQDFFSKYRN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . :* . :*****.: ** ::. :*. . ** :*.****: : : *:*:*: **:*:: . :* . : *. ** ::: * *:*:*: * *: :*. ** :* :** * . ::::*: *** . :*.:: .*:::.*******:*: : . : ***:*: *: : *:. :* . * .* :******** * : : * : .* . :::*****:*:: . :* *:**: .: ::.*: * ** .*** ****:*: .:. :: : * : :*. ..**. :. :* ** : *: *: : :* . ::. * : ***** **:: :* :*: :. ** *:. *** :*** ********. **:*.* *:*. : : . ** * :* ", "identical_positions": 143, "similar_positions": 139, "identity": "23.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121214-96", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55083-1", "uniprot_id": "MFAP4_HUMAN", "id": "P55083-1", "name": "Microfibril-associated glycoprotein 4", "aln": "MKALLALPLLLLLS--TPPCAPQVSGIRGDALERFCLQQPLDCDDIYAQGYQSDGVYLIYPSGPSVPVPVFCDMTTE-----GGKWTVFQKRFNGSVSFFRGWNDYKLGFGRADGEYWLGLQNMHLLTLKQKYELRVDLEDFENNTAYAKYADFSISPNAVSAEEDGYTLFVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRSCHFANLNGFYLGGSHLS-YANGINWAQWKGFYYS-LKRTEMKIRRA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D1H9-1", "uniprot_id": "MFAP4_MOUSE", "id": "Q9D1H9-1", "name": "Microfibril-associated glycoprotein 4", "aln": "MKALPALPLMLMLLSMPPPCAPQASGIRGDALEKSCLQQPLDCDDIYAQGYQEDGVYLIYPYGPSVPVPVFCDMTTE-----GGKWTVFQKRFNGSVSFFRGWSDYKLGFGRADGEYWLGLQNLHLLTLKQKYELRVDLEDFENNTAYAKYIDFSISPNAISAEEDGYTLYVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRSCHFANLNGFYLGGSHLS-YANGINWAQWKGFYYS-LKRTEMKIRRA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "R4GES4-1", "uniprot_id": "R4GES4_DANRE", "id": "R4GES4-1", "name": "", "aln": "-MAMTVFVVALLSV----FTASVVSGFK-----------PFDCSEIYKSGQTGSGIYSIYPAG-DTPVWVYCEMVSRMMDGFNGGWTVFQRRMDGSINFYQPWEEYKKGFGTTEGEYWLGLENLYQLTRQKKFMLKVDLEDFTGRRGFAQYSSFSVG-----SEAEGYKLQVSAFTDGGAGDSLAYHNQMKFSTFDKDQDNSVKNCAKLNLGAFWYRDCHHTNPNGVYLWGEDATIFGIGNVWYAWTNKYATGLKSITMKIKPVS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: .: : *: *. .**:: *:**.:** .* .*:* *** * ..** *:*:*.:. .* *****:*::**:.*:: *.:** *** ::*******:*:: ** ::*: *:****** .. .:*:* .**:. :* :**.* *:.* ********:**. ******:*** *:*** *. ****:*.**.:* **.** *.. : :. * * *.. * : ** ***: . ", "identical_positions": 112, "similar_positions": 74, "identity": "42.26%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121219-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8XPU7-1", "uniprot_id": "A0A8J8XPU7_RAT", "id": "A0A8J8XPU7-1", "name": "B-cell antigen receptor complex-associated protein beta chain", "aln": "MKLPSRVPGEMVPPLGLNLHGRKGPNGEEVERRKVAARADTQLHVLPQTLLGLRDRAVTMATLVLSPVPCHWLMFLLLLLSGEPVPAMTKSDQPPIFQGSPCSKIWQHPRFAAKKRSSMVKFHCHTD----YSGVMTWFRQKGN-QRPQELFPEDGHISQTRNGSVYTLTLQNIQYEDNGIYFCQQKCNSTEPDVTDGCGTELLVLGFSTLDQLKRRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSK----AGMEEDHTYEGLNIDQT--ATYEDIVTLR-TGEVKWSVGEHPGQE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15530-1", "uniprot_id": "CD79B_MOUSE", "id": "P15530-1", "name": "B-cell antigen receptor complex-associated protein beta chain", "aln": "-----------------------------------------------------------MATLVLSSMPCHWLLFLLLLFSGEPVPAMTSSDLPLNFQGSPCSQIWQHPRFAAKKRSSMVKFHCYTN----HSGALTWFRKRGS-QQPQELVSEEGRIVQTQNGSVYTLTIQNIQYEDNGIYFCKQKCDSANHNVTDSCGTELLVLGFSTLDQLKRRNTLKDGIILIQTLLIILFIIVPIFLLLDKDDGK----AGMEEDHTYEGLNIDQT--ATYEDIVTLR-TGEVKWSVGEHPGQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40259-1", "uniprot_id": "CD79B_HUMAN", "id": "P40259-1", "name": "B-cell antigen receptor complex-associated protein beta chain", "aln": "-----------------------------------------------------------MARLALSPVPSHWMVALLLLLSAEPVPAARSEDRYRNPKGSACSRIWQSPRFIARKRGFTVKMHCYMNS---ASGNVSWLWKQEMDENPQQLKLEKGRMEESQNESLATLTIQGIRFEDNGIYFCQQKCNNTS-EVYQGCGTELRVMGFSTLAQLKQRNTLKDGIIMIQTLLIILFIIVPIFLLLDKDDSK----AGMEEDHTYEGLDIDQT--ATYEDIVTLR-TGEVKWSVGEHPGQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ID76-1", "uniprot_id": "A0A0R4ID76_DANRE", "id": "A0A0R4ID76-1", "name": "", "aln": "-------------------------MSVLICMFLRSIFTALDLHLLAEAGLCSG-ELYSFCSLSVTDVYITFRGGFEDFNIMHHFLLGFSVMALIYLSAEGSIIVFQKPRFIGVKTGRTVIIYCVPSNPTRGPARVQWFKNKNY--QSSLTNDQRITINDRNNDKNASITLKKVETEDSGTYVCKLND-------TFGPGTALQVSRYSEPHAVLMRSRVKDVIIFLQAFLLVLCIVVPLVRLYKLEKKEEAEYEEPEDDHIYEGLEIEQVGGDVYEDISTFAQSSDAAWQV-ESPCQE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * :: : : : : . . . ... . ::* *** . * . * ::* . .. : *: :: ... : : : .* . ::*:: :. **.* *.*: : . ** * * :* : *. :** **::*::*::* *:**:. * . :. : *:** ****:*:*. .**** *: :.:. *.* * * **", "identical_positions": 53, "similar_positions": 75, "identity": "17.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121219-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A904-1", "uniprot_id": "D4A904_RAT", "id": "D4A904-1", "name": "N-acetylglutamate synthase, mitochondrial", "aln": "MTCHTPNAPRSHSGPPIPPRPESDPAQLNGKLRTPSVVRSRPTVTCGWGRPVGLVVVMATAWVATALRSAAAARRLRSPGGPGGSRRLSGSARRRGARSASPGRRLSTARAH----VEDNEGTKGRVQSPAVEEPPWTP---LPTPLESPAPPAGKSLVQRDIQAFLNQCGASPGEARHWLTQFQT----CYHSVDKPFAVVEVDEEVFGCPQAVSRLAFALAFLQRMDMKPLVVLGLPAPTAPSG-----------------CLSFWEAKAQLAQSCKVLVNELRHNAATAVPFFGGGSVLSAAEPAPHASYGG-IVAVETDLLQWCLESNSIPILCP---IGETAARRSVLLDSLEVTASLAKALQPTKIIFLNNSGGLRDTSQ-KILSNVNLPADLDLVTNAEWLSTKERQQ---IRLIVDVLSRLPHYSSAVITAASTLLTELFSNKGCGTLFKNAERMLRVRS----LDSLD-----QGRLVNLVNASFGKKL-REDYLESLRPRLHSIYVSEGYNAAAILTVEPVL-GGTPYLDKFVVSSSRQG-QGSGQMLWECLRRDLQ-TLFWRSRVTNPINPWYFKHSDGSFSN-------------KQWIFFWFG-----LADIRDSYELVNHAKGLPDSFCKPASDP--------GS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4H7-1", "uniprot_id": "NAGS_MOUSE", "id": "Q8R4H7-1", "name": "N-acetylglutamate synthase, mitochondrial", "aln": "---------------------------------------------------------MATAWVATALRSAAAARRLRSPGGPGGSRRLSGSARRRGAKSASPGRRLSTARAH----AEDAEGAKGRVQSPAVEEPSWTP---LPTPLESPAPPAGRSLVQRDIQAFLNQCGASPGEARHWLTQFQT----CYHSVDKPFAVMEVDEEVIRCPQAVSRLAFALAFLQRMDMKPLVVLGLPTPTAPSG-----------------CLSFWEAKAQLAQSCKVLVDELRHNAATAVPFFGGGSVLSAAEPAPHASYGG-IVAVETDLLQWCLESNSIPILCP---IGETAARRSVLLDSLEVTASLAKALQPTKIIFLNNSGGLRNNSQ-KILSNVNLPADLDLVTNAEWLSIKERQQ---IRLIVDVLSRLPHYSSAVITAASTLLTELFSNKGCGTLFKNAERMLRVRN----LDSLD-----QGRLVNLVNASFGKKL-REDYLESLRPRLHSIYVSEGYNAAAILTVEPVL-GGTPYLDKFVVSSSRQG-QGSGQMLWECLRRDLQ-TLFWRSRVTNPINPWYFKHSDGSFSN-------------KQWIFFWFG-----LADIRDSYELVNHAKGLPDSFCKPASDP--------GS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N159-1", "uniprot_id": "NAGS_HUMAN", "id": "Q8N159-1", "name": "N-acetylglutamate synthase, mitochondrial", "aln": "---------------------------------------------------------MATALMAVVLRAAAVAPRLRGRGGTGGARRLSCGARRRAARGTSPGRRLSTAWSQPQPPPEEYAGADDVSQSPVAEEPSWVPSPRPPVPHESPEPPSGRSLVQRDIQAFLNQCGASPGEARHWLTQFQT----CHHSADKPFAVIEVDEEVLKCQQGVSSLAFALAFLQRMDMKPLVVLGLPAPTAPSG-----------------CLSFWEAKAQLAKSCKVLVDALRHNAAAAVPFFGGGSVLRAAEPAPHASYGG-IVSVETDLLQWCLESGSIPILCP---IGETAARRSVLLDSLEVTASLAKALRPTKIIFLNNTGGLRDSSH-KVLSNVNLPADLDLVCNAEWVSTKERQQ---MRLIVDVLSRLPHHSSAVITAASTLLTELFSNKGSGTLFKNAERMLRVRS----LDKLD-----QGRLVDLVNASFGKKL-RDDYLASLRPRLHSIYVSEGYNAAAILTMEPVL-GGTPYLDKFVVSSSRQG-QGSGQMLWECLRRDLQ-TLFWRSRVTNPINPWYFKHSDGSFSN-------------KQWIFFWFG-----LADIRDSYELVNHAKGLPDSFHKPASDP--------GS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FCP8-1", "uniprot_id": "NAGS_DANRE", "id": "E7FCP8-1", "name": "N-acetylglutamate synthase, mitochondrial", "aln": "---------------------------------------------------------MAKVNSGSSGCRAMVMAGQFWTKPFALSSQRSGPHRRSAAEVN---RRMSSSRTAG-------HGSKTPLWS---QQESYNH-----SSLGERSAWSNRTLIYRDVKAFLREIGGDPREARYWLTHFQR----AGSTP--AFAVLEVDPSVFDSHEMVQSLAFGLSFLQRMDMKLVVVMGLPAEITEDDHTR-------------SATDSPLARTVMVKHCQALTEALQDNSANVMPFFSSEALLQLQDNPLDGSSSGPSVVVDSALLQWTLDCRVIPLVCP---VGRDTTGRSSVLRSIQVTTAISQTLQPLKVIFLNSSGGIRNQNH-KVLGLVSLPGDLPALSCAEWLNEVEQKR---IGSIAELLNLLPVESSAVLTSANTLLTELFSHKGSGTLFKNGDPIRRYSS----LEDID-----VDRLLALINKSFEKNL-REDYIASLEGRLHSVYLSEGYSAAAIITTEPVN-SGTPYLDKFVVSSSKQG-QGTGQILWECIRQDFS-KLFWRSRTTNRINPWYFKHCDGSFVN-------------GHWIVFWLG-----LSDIRESYELVEFAKSHPDSFCSLSTTETKPLQQHHGS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q01217-1", "uniprot_id": "ARG56_YEAST", "id": "Q01217-1", "name": "Protein ARG5,6, mitochondrial", "aln": "---------------------------------------------------------MPSASLLVSTKRLNASKFQKFVSSLNKSTIAGFASVPLRAPPSVAFTRKKVGYSKR-----------------------------------YVSSTNGFSATRSTVIQLLNNIS-TKREVEQYLKYFTS----VSQQQ---FAVIKVGGAIIS--DNLHELASCLAFLYHVGLYPIVLHGTGPQVNGRLEAQGIEPDYIDGIRITDEHTMAVVRKCFLEQNLKLVTALEQLGVRARPITSGVFTADYLDKDKYKLVGN-IKSVTKEPIEASIKAGALPILTS---LAETASGQMLNVNADVAAGELARVFEPLKIVYLNEKGGIINGSTGEKISMINLDEEYDDLMKQSWVKYGTKLK---IREIKELLDYLPRSSSVAIINVQDLQKELFTDSGAGTMIRRGYKLVKRSS----IGEFPSADALRKALQRDAGISSGKES-VASYLRYLENSDFVSYADEPLEAVAIVKKD----TNVPTLDKFVCSDAAWL-NNVTDNVFNVLRRDFP-ALQWVVSENDANIAWHFDKSQGSYLK-------------GGKVLFWYG-----IDDINTISELVENFVKSCDTASTLNSSASSGVFANKKSARSYSTRSTPRPEGVNTNPGRVALIGARGYTGKNLVSLINGHPYLEVAHVSSRELKGQKLQDYTKSEIIYESLQIQDIRKLEEQNAVDFWVMALPNKVCEPFVETIQSVHGKSKIIDLSADHRFVSESDWAYGLPELNDRAKIANAAKIANPGCYATGSQLTISPLTKYINGLPTVFGVSGYSGAGTKPSPKNDPKFLNNNLIPYALSDHIHEREISARIGHNVAFMPHVGQWFQGISLTVSIPIKKGSLSIDEIRKLYRNFYEDEKLVHVIDDIPLVKDIEGTHGVVIGGFKLNDAEDRVVVCATIDNLLKGAATQCLQNINLAMGYGEYAGIPENKIIGV", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40360-1", "uniprot_id": "NAGS_YEAST", "id": "P40360-1", "name": "Amino-acid acetyltransferase, mitochondrial", "aln": "------------------------------------------------------------MWRRIFAHELKYDQPNASSKNLILSVLNTTATKREAKDYLSKYTNDSGQHNHCLFFIRDLHKVAPAILSQFSSVIKRLGMLGLRPMFVIPPSPTHVNIQAELLDSIVTEADLKPLHLKEGLTKSRTGLYHSVFSQESRFFDIGNSNFIPIVKPYVYNEETASEFMTKDVVKFMDCLCQGNIPHIDKFFILNN----------AGGIPSGERNDNAHVFINLSQELEHLSSSLSHNISTLTKREPRSQNLLHRMEVYVKKDEISSLECEYHDHLENLLLMDKVLSNLAATATGLITTVKAAALSSDRKNPLVYNLLTDRSLISSSLPRFKKKDGEIDSPANMFDDHAWYELPSQQVNAAPSNSDAVLVTTVLKKGVHIKTYDYKTLTQFNSIGLPKKFHVPEKGAKPSSNSPKLD--------INKFKSIIDQSFKRSLDLHDYIKRINGKIATIIVIGDYEGIAILTYEGSEENSFVYLDKFAVLPHLKGSLGISDIIFNLMFKKFPNEILWRSRKDNVVNKWYFQRSVAVLDLSIDLDPEHCDEKQSQFKLFYYGNPQYAKRALRDKKRLREFMRSVRDIKPSWENEKNIS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . : :: : . . . *. * : . : : *: : : : : . * *.. . . . :: . :: :.. :: : : .: : .* *.. . : . .: . * . : :* ... : . *. * . :: : . : : . * :. .*: :. .. **:. : . ****. . : ::: : :.: : * : *:*.:. . .*: * :. .* : * . . ", "identical_positions": 26, "similar_positions": 106, "identity": "2.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121219-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UQL6-1", "uniprot_id": "HDAC5_HUMAN", "id": "Q9UQL6-1", "name": "Histone deacetylase 5", "aln": "-------------------MNSPNESDGMSGREPSLEILPRTSLHSIPVTVEVKPVLPRAMPSSMGGGG---GGSPSPVELRG----ALVGSVDPTLREQQLQQELLALKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAKQQQEMLAAKRQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLP-LPGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGAGPGASSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMLP-QHRALPLDSSPNQFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALE------GDGSPHGHASLLQHVLLLEQARQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQLQLGKILTKTGELPRQPTTHPEETEEELTEQQEVLLGEG-ALTMPREGSTESESTQEDLEEEDEEDDGEEEEDCIQVKDEEGESGAEEGPDLEEPGAGYKKLFSDAQPLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGGMKSPPDQP--VKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLSKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLLELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLNVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAHEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPNINAVATLEKVIEIQSKHWSCVQKFAAGLGRSLREAQAGETEEAETVSAMALLSVGAEQAQAAAAREHSPRPAEEPMEQEPAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z2V6-1", "uniprot_id": "HDAC5_MOUSE", "id": "Q9Z2V6-1", "name": "Histone deacetylase 5", "aln": "-------------------MNSPNESDGMSGREPSLGILPRTPLHSIPVAVEVKPVLPGAMPSSMGGGG---GGSPSPVELRG----ALAGPMDPALREQQLQQELLVLKQQQQLQKQLLFAEFQKQHDHLTRQHEVQLQKHLKQQQEMLAAK---------RQQELEQQRQREQQRQEELEKQRLEQQLLILRNKEKSKESAIASTEVKLRLQEFLLSKSKEPTPGGLNHSLPQHPKCWGAHHASLDQSSPPQSGPPGTPPSYKLP-LLGPYDSRDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAVEITGTGPGVSSVCNSAPGSGPSSPNSSHSTIAENGFTGSVPNIPTEMIP-QHRALPLDSSPNQFSLYTSPSLPNISLGLQATVTVTNSHLTASPKLSTQQEAERQALQSLRQGGTLTGKFMSTSSIPGCLLGVALE------GDTSPHGHASLLQHVCSWT-GRQQSTLIAVPLHGQSPLVTGERVATSMRTVGKLPRHRPLSRTQSSPLPQSPQALQQLVMQQQHQQFLEKQKQQQMQLGKILTKTGELSRQPTTHPEETEEELTEQQEALLGEG-ALTIPREGSTESESTQEDLEEEEEEEE-EEEEDCIQVKDEDGESGPDEGPDLEESSAGYKKLFADAQQLQPLQVYQAPLSLATVPHQALGRTQSSPAAPGSMKSPTDQPTVVKHLFTTGVVYDTFMLKHQCMCGNTHVHPEHAGRIQSIWSRLQETGLLGKCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAMLPCGGIGVDSDTVWNEMHSSSAVRMAVGCLVELAFKVAAGELKNGFAIIRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLSVGKVLIVDWDIHHGNGTQQAFYNDPSVLYISLHRYDNGNFFPGSGAPEEVGGGPGVGYNVNVAWTGGVDPPIGDVEYLTAFRTVVMPIAQEFSPDVVLVSAGFDAVEGHLSPLGGYSVTARCFGHLTRQLMTLAGGRVVLALEGGHDLTAICDASEACVSALLSVELQPLDEAVLQQKPSVNAVATLEKVIEIQSKHWSCVQRFAAGLGCSLREAQTGEKEEAETVSAMALLSVGAEQAQAVATQEHSPRPAEEPMEQEPAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FH14-1", "uniprot_id": "E7FH14_DANRE", "id": "E7FH14-1", "name": "Histone deacetylase", "aln": "MLLKPTVPGLCAMLQTIYETESCFSSDSTSSRERPVELLPQSRSTSMPSTVDVKTLLPSGMQSPVGGGGDQGGGSGGPVDLRTDPRLSALSAVDPSLREKQLQHELLLLKQQQELQKQLLFAEFQKQHEVLTRQHEVQLQEHLKQQQEILAAK---------RQQELEQKRKLEQQRHEEMEKQRLEQQLIMLRNKEKGKESAIASTEVKLKLQEFLLSK-KEPGPGGLNHSFPQ--KCWGAHHTSLEQSSPPQSNTPGTPPSYKLPPLLGSYEGKDDFPLRKTASEPNLKVRSRLKQKVAERRSSPLLRRKDGTVISTFKKRAIEIS-----VSSMCSSAPGSGPSSPNSSNCAIAENGSSGSVPNIHAEQLRSLHQSLTGDGAPSPLSLYTSPSLPNISLGLPA-----NAHITAPQKLSAQQEAERQTIQSLRQGGALTGKFISTSSLPTCLSTGAPHDPEPPAASNSHSSHSSLLQHVLLLEQARQQSALLAVPMYGQSPLVTGERVSNNMRTVNKLPRHRPLSRTQSAPLPQTPQALQHLVMQQQHQHFLEKQK--HYQLNKILSKGTDLPRQPPTHPEETEEELTETAEMQDERGEGPDHVREG-LQKDSSGETTPPSERIVPLKGESTESDLEEEDDEDEAVELRECDEDAP--YGQYLDQQHVQQLNVFQASLSITGMPHRPLGRAQSSPVTS-SLKGTTLNEVPIKHLFTTGLVYDTFMLKHQCMCGNTNIHPEHAGRIQSVWSRLQETGLLGRCERIRGRKATLDEIQTVHSEYHTLLYGTSPLNRQKLDSKKLLGPISQKMYAVLPCGGIGVDSDTVWNEMHSSGAVRMAVGCVIELAFKVAAGELKNGFAVVRPPGHHAEESTAMGFCFFNSVAITAKLLQQKLGVGKILIIDWDIHHGNGTQQAFYNDPNVLYISLHRYDDGNFFPGSGAPEEVGVGPGEGFNVNIAWTGGVEPPMGDVEYLTAFRTVVMPIANEFSPDVVLVSAGFDAVEGHQSPLGGYNVTAKCFGHLTKQLMKLAGGRVVLALEGGHDLTAICDASESCVEALLGDELNPLPLTVLQQKPCPKATASLERVIEIQSKHWTSLQRLAPTVGQSLLDAQRREKDEADTLTAMASLTVDNEQQ---TTSTETSRSAEEPMEEEPVL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .**. *.** .: :**:: *:* :*:**.:** .* *.:**** *** .**:** : ..:**:***:***:*** *****:**************: **********:*******:**** *******:*: ****:**:*********::******.************:******** *** *******:** *******:**:*******..********** * *.*:.:************************************************:**: .**:*.*************:.:***** :****** :* : *::*. *.:*. :*************** * *:*:**. ***:*******::*******:*****:****:* ** * . .. * .*:****** .****:*:***::***********:..****.*************:****:*****:********:****** : **.***:* :*.***.************ * .* . *** :.:*: * .:. : *. ::::*:.*. . * : :* .. : * * :* *:*:**.**:: :**:.***:****.:. .:*... : :*******:****************::**********:**********.:***************************************************:********************.********::****************::********************************.***:**:******************.**********:************** *** *:***:******:**:*****************:******************* ******.***:******:***.************************:**.***. **:** :****** :*.*:**:*********:.:*::*. :* ** :** *.:**:*::*** *:*. ** :: .:.*.******:**.*", "identical_positions": 787, "similar_positions": 200, "identity": "67.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121219-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AJF7-1", "uniprot_id": "A0A8I6AJF7_RAT", "id": "A0A8I6AJF7-1", "name": "", "aln": "--------------------------------------------------------MAAMAPALTDAAAEAHHIRFKLAP-----------------------PSSTLSPGSAENNGNAN-ILISANGTKRKAIAA-----EDPSLDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYELRAELLGRQPVLEFSLENLRTMNTSG--------QTALPQAPVNGLAKKLTKSSTHSDHDNSSSLNGGKRSLTSSSLQGGEVGGSDSGN---LKGGMTNCTLPHRSLDTQHTTLYSNNS-----TVNKSPVNSMEQPALQGSSRLSPSTDSCSNLTSVKLEVKKSPLSSILFSALD---------SDTRITALLRRQADIEIRARRLQKRLQVVQAKQVERHLQHQLGGFLEKTLSKLPNLESLRSRSQLMLTRKAEAALRKAASETATSEGLS-NFLKSDSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTRADPEQCHVPLKRRSEWRWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLIVLGEASFPDHTT-DLLS-LSSEVKTDHGSD---------KLIESVSQPSENHGIPVS-HITESLSTKTCGALRPVNGVVNSLQPVLADQVPGDSSDAEEQIHKKQRLN---------LVSSSS-DGTCVAARTRPVLSCKKRRLVRPSSIVPLSKKVHRN--IRSGCDVNPS-CALCGSGSVNTMPPEIHYEAPLLERLSQLDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPTKKFSLKHRAPMPCSLSDPVRKDRHKLVNSFLTTSKLSHHQTRPDRTHRQHLDDVGAVPMVER---------------------VTAPKAERLLHLPPPVHDPTHSKLRLRDHSSERS-----------EVLKHHTDMSSSS-YLTATHHSPHSPLVRQLSTSSDTSTPTS-----------------------SSSQVAASTS-QPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG----------------------------------------------------------------------------------------------------------------------------------------------------------------------SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLGSANPSTPQPAS--PDVSSSHSLSEFSHGQSPRSPISPELHSAP--LTPVARDSLRHLASEDTRCSTPELG--LDEQSVQPWERRTFPLAYSPQAECDEQLDAQ-------------------------------DTAARCTRRTSGSKTGR-----------ETEVAPTSPPVVPLKSRHLAATVAAQRPTHR----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TG1-1", "uniprot_id": "KANL1_MOUSE", "id": "Q80TG1-1", "name": "KAT8 regulatory NSL complex subunit 1", "aln": "--------------------------------------------------------MAAMAPALTDAAAEAHHIRFKLAP-----------------------PSSTLSPGSAENNGNAN-ILISANGTKRKAIAA-----EDPSLDFRNNPTKEDLGKLQPLVASYLCSDVTSVPAKESLKLQGVFSKQTVLKSHPLLSQSYELRAELLGRQPVLEFSLENLRTMNTSG--------QTALPQAPVNGLAKKLTKSSTHSDHDNSSSLNGGKRSLTSSSLQGGEVGGPDSGN---LKGGMTNCTLPHRSLDIQHTTLYSNNS-----TANKSSVNSMDQPALQGSSRLSPSTDSSSNLTNVKLEVKKSPLSSILFSALD---------SDTRITALLRRQADIEIRARRLQKRLQVVQAKQVERHLQHQLGGFLETTLSKLPNLESLRSRSQLMLTRKAEAALRKAASESATSEGLS-NFLKSDSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTRADPEQCHVPLKRRSEWRWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLIVLGEAPFPDHTT-DLLS-LSSEVKTDHGRD---------KLIESVSQPSENHGILVS-NITESLSTKSCGAPRPVNGVVNSLQPVLADQVPGDSSDAEEQLHKKQRLN---------LVSSS--DGTCVAARTRPVLTCKKRRLVRPSSIVPLSKKVHRN--VRSGCDVNPS-CALCGSGSVNTMPPEIHYEAPLLERLSQLDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPTKKFSLKHRATMPCSLSDPVRKDRHKLVNSFLTT-----------------------------------------------------------------------------------------------AMLKHHTDMSSPS-YLTATHHPPHSPLVRQLSTSSDTSTPTS-----------------------SGSQVAASTS-QPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDVQSLKG----------------------------------------------------------------------------------------------------------------------------------------------------------------------SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLGSANPSTPQPAS--PDVSSSHSLSEFSHGQSPRSPISPELHSAP--LTPVARDSLRHLASEDTRCSTPELG--LDEQSVQPWERRTFPLAYSPQAECEEQLDAQ-------------------------------DTAARCTRRTSGSKTGR-----------EAEVAPTSPPVVPLKSRHLAATVTAQRPAHR----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z3B3-1", "uniprot_id": "KANL1_HUMAN", "id": "Q7Z3B3-1", "name": "KAT8 regulatory NSL complex subunit 1", "aln": "--------------------------------------------------------MAAMAPALTDAAAEAHHIRFKLAP-----------------------PSSTLSPGSAENNGNAN-ILIAANGTKRKAIAA-----EDPSLDFRNNPTKEDLGKLQPLVASYLCSDVTSVPSKESLKLQGVFSKQTVLKSHPLLSQSYELRAELLGRQPVLEFSLENLRTMNTSG--------QTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNGGKRALTSSALHGGEMGGSESGD---LKGGMTNCTLPHRSLDVEHTTLYSNNS-----TANKSSVNSMEQPALQGSSRLSPGTDSSSNLGGVKLEGKKSPLSSILFSALD---------SDTRITALLRRQADIESRARRLQKRLQVVQAKQVERHIQHQLGGFLEKTLSKLPNLESLRPRSQLMLTRKAEAALRKAASETTTSEGLS-NFLKSNSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTRADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLIVLGEVPPPEHTT-DLFLPLSSEVKTDHGTD---------KLIESVSQPLENHGAPIIGHISESLSTKSCGALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLN---------LVSSSS-DGTCVAARTRPVLSCKKRRLVRPNSIVPLSKKVHRNSTIRPGCDVNPS-CALCGSGSINTMPPEIHYEAPLLERLSQLDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHRAPMPGSLPDSARKDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVER---------------------VTAPKAERLLNPPPPVHDPNHSKMRLRDHSSERS-----------EVLKHHTDMSSSS-YLAATHHPPHSPLVRQLSTSSDSPAPAS-----------------------SSSQVTASTSQQPVRRRRGESSFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDLQSLKG----------------------------------------------------------------------------------------------------------------------------------------------------------------------SPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLGSANPSTPQPAS--PDVSSSHSLSEYSHGQSPRSPISPELHSAP--LTPVARDTPRHLASEDTRCSTPELG--LDEQSVQPWERRTFPLAHSPQAECEDQLDAQ-------------------------------ERAARCTRRTSGSKTGR-----------ETEAAPTSPPIVPLKSRHLVAAATAQRPTHR----------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QUH6-1", "uniprot_id": "F1QUH6_DANRE", "id": "F1QUH6-1", "name": "", "aln": "--------------------------------------------------------MAAMAPALTDAPAEAHRIRFKLAP-----------------------PSSTLSPSGVEGSGTTNHILVSSNGTVKRKASE-----ERPSR---------GAGPCKPLVTSYHCSDD---------KLQGVL-----LQTHSILPS------LIPRKHQALELSEEQLKSIMSAGGG-----GGPTVQSPTVNGVAKKVTKP---SDRDNAVTLNGGQHNVKQDLSNQAQIVNSTRGM---TRNGPHRDGVEQQ----QPSTCESQNC-----PSNG------EPPATSPASVSSFTEDKVSDCQPLVSEDTLLHLHGIQQVPLDGFGTE----LSDRTQHSQSRQGEIEARLRRLRKRLQVVQAKQVERHVQQQLGGLLESTLG---ALDARRPRS-----RYGDNGITPQE-----RDELG-RFLKGGSMPAELERLSLSCTTNLRSAEFAFDSDATESSSGGDTDVDEDELARVDIEQRHIPLCRRAENRYAVDRAAIISHWNWLQAQVSDLEYRIRQQTDIYRQIRSSKGSAVLGESSVCESVPEDSNDSRTNTITCPVPRE---------HDVVGVEASLSSNG-----IVTETGLRKSCGPIRQVNGVINSFR---------SDSPVTSDLDEQSRLG---------SVPFPTNDNTCVAARTRPLLSYRKRRVLRPGSLTSLNRKAQRSVAPRCGCELNSQ-CVMCSGRAP--PAADTQHQLPLLDRLAQFDPCVHPILSFTDDVMMNLHMQRVLKGHWQNRPLEKIKPIKKISLKHKLCLGSRISDPSSKDKHRLINSHLSTVRLPHHKVRSEKVSRQPLDIPMSASKLD----------------------------SRQHFRHSSSFDRSLSRKRPREPSLDRSE----------NAPKLYMDLGSPCPSLSTLTTPTHSPLMRQPSAS-ETSTPLH-----------------------LNSNAAATIR-----RRRGESPFDINNIVIPMSVAATTRVEKLQYKEILTPSWREVDVFAKPI----------------------------------------------------------------------------------------------------------------------------------------------------------------------AEEDDAVEVEDLSDVTFSQLHLPLQEQERSRWSWTASNIAKRRGSRSYKSVDGRTTPLLCGTNPSTPQPSS--PDTPHFHLLHEYSSVASPTSPASPEMLMLTGLHTPASRDSHRLLSNEDTRCSTPDTIEEMTPQPVQPWERRTFPLDVEPQQEVEIHLSPTG------------------------------ERQCRTIRRVSGCRSSKS----------ESDTGPSSP---LCDDGTKQKPTNPPKPTHR----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E2QD16-1", "uniprot_id": "E2QD16_DROME", "id": "E2QD16-1", "name": "", "aln": "MAPALTAEPLSPKEKLTSTASPSARSSSESGGVGCAVGLVKKPATPTPATATTRITRSSAAAASVTASPHLQQQRSSLAINNKRKSGNAKASNEPMGLSTAPTPHSTTSPNPSTDTAAASTSAVEHNNNDSNSTSAGNSTSADNSSTPKDNSTAQLLADLTINFEETISAEICLRKTLPDVSLGKEPVPPASVLAVATSSTSAGSALSLSAVDEVTKIEIDNIEERLSQLDGNATGRPEEHVAPPSVPVPVQEAPNTPTRPQAPPSAHLESPQPARTQQQSIQQMTPQSTTSSNNFLKDGAAGAVLEDQDIEEVLKALKTFDGGHVNPDTICEFFDEVWEEAAPAAPLPPAPPENVVDVPGAKPSCSGILVSGSNISQPNVIIKQEQRPWQESHAELEQQQHVISRRIEFLLRRMRKLQARAMCRHASEEVVGIMEWSARSSHKAPVPARSSTLTEQEATVLSIVSGRPSSTFWEEQNKHPLPASQMSNVIRHIATAAKHQQICHSASGSSATLAPSSSWYNSCNSSALPMKRPRKNQLDASVATGATPTAPAPGAVTSRQAAGTTGSATGSNTPRADDIVPGYDTYVTNELTHVSGLLHTELREVQNAIDSDATESSSGGESADEMVTYNNNQQLSLPITRRAVWRYSRDRAAIALRWSWLCSQLTDLEMKIRQHSDLYMDLTQSKGEIQLESTAKTSPSLAQPANGIKEEPGSDYLCSRARPLVLSEFRKRKLFQTTNMHTISKKAARPSNIKCGCQWPQVPCTLCTGRTDPTAPRDLVETMMPQNRVALLDAGYHPVLSFASDVSQSVHLEAVARQPDWQYRVMRSQPKAIVKAMWKAERETIASGGVGGQGGSRRSGDAAKRRYIRRKERNNNSNKEAGSGAKAAAVAAGGAGGNGSSSVGGGDSGNGTGTATTSSSTTPTTTPLVANTAARGKRQPQHPTGANSSSSLWPDSRQRQRQRHHSPSSTSISALSGAKKARKSATNSSSSNSTQQQQNHHGTKINNHHLNGYGDQWGEQSRSRRNSSPSNSHKNERTSERRVRPIYDINNIVIPYSMLAQSKMEIIPYKEIPIPKWRIVDSDNDKGKHSSDESMERKLSNGCVASKSEELAKQQLPPPPDQDQEQPALQPPKVNGLKENQAVKHNNNNNTNNNNNKNGLVNGNAKKDELKAAEDHDTQSKEDDDPKEKVVKPKLNGNLIKNPIDKTAETQDKIAQPAPEPPLPKRPKLETPTSNEVTKANGQLVQQQLESRESEEEPQHVDEDLSDEAFIMRHQRALLEERRRFETFLKFPWSTRSRANRRVDSRAESSGANTPDPASPAPHLGGPGHDNESIPSPLAYPLDAFNESGELLTGGQARQARRRTTSSKLKDQLERRSTTPDLR-ESYTVMPSPFEPLNFPLSDEVYQRLLAETYAPPRSMTVSKRAKSKSISSNCDGGNTFTGGSGSRRSSKCKIKPNGQLNGQLNGHPAAAKLNGIDAANEGGISEPEEEEMLLEDEDDDYPKHHLAPLDDEEPSTPDVEHELYDSAIDAYLADPEALEEDMGEDPFEDDDPNDPEWKTRTEGVRSRRI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 114, "similar_positions": 306, "identity": "7.26%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121219-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AJF7-1", "uniprot_id": "A0A8I6AJF7_RAT", "id": "A0A8I6AJF7-1", "name": "", "aln": "MAAMAPALTDAAAEAHHIRFKLAPPSS--------------------TLSPGSAENNGNANILISANGTKRKAIAAEDPSLDFRNNPT-------KEDLGKLQPL-----VASYLCSDVTSVPS----KESLKLQGVFSKQTVLKSHP---------------------LLSQSYELRAEL-----LGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSSSLNG--------------------------------------GKRSLTSSSLQGGEVGGSDSGNLKGGMTNCTLPHR--SLDTQHTTLYSNNSTVNKSPVNSMEQPALQGSSRLSPSTDSCSNLTSVKLEVKKSPL---SSILFSALDSDTRITALLR--RQADIEIR-------ARRLQKRLQVVQAKQVERHLQHQLGGFLEK---------------------------------------------------------------------------TLSKLPNLESLRSRSQLMLTRKAEAALR-KAASETATSEGLSNFLKS--------------------------DSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTRADPEQCHVPLKRRSEWRWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLIVLGEASFPDHTTDLLS---------------LSSEVKTDHGSDKLIESVSQPSENHGIPVS-HITESLST------------KTCGALRPVNGVVNSLQPVLADQVPGDSSDAEEQIHKKQRLNLVSSSSDGTCVAARTRPVLSCKKRRLVRPSSIVP--------------------LSKKVHRN---IRSGCDVNPSCALCGSG-------------------------SVNTMPPEIHYEAPLLERLSQLDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPTKKFSLKHR-APMPCSLSDP-----VRKDRHKLVNSFLTTSKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLHLPPPVHDPTHSKLRLRDHSSERSEVLKHHTDMSSS--SYLTATHHSPHSPLVRQLSTS---SDTSTPTSSSSQVAASTS-QPVRRRRGESSFDINN-------------------------------------------IVIPMSVAATTRVEKLQYK---------EILTPSWREVDLQS---------LKGSPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLGSANPSTPQPAS--PDVSSSHSLSEFSHGQSPRSPISPELHSAPLTPVARDS-LRHLASEDTRCSTPELGLDEQSVQP--WERRTFPLAYSPQAECDEQLDAQDTAARCTRRT------------------SGSKTGRETEVAPTSPPVVPLKSRHLAATVAAQRPTHR----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TG1-1", "uniprot_id": "KANL1_MOUSE", "id": "Q80TG1-1", "name": "KAT8 regulatory NSL complex subunit 1", "aln": "MAAMAPALTDAAAEAHHIRFKLAPPSS--------------------TLSPGSAENNGNANILISANGTKRKAIAAEDPSLDFRNNPT-------KEDLGKLQPL-----VASYLCSDVTSVPA----KESLKLQGVFSKQTVLKSHP---------------------LLSQSYELRAEL-----LGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSSSLNG--------------------------------------GKRSLTSSSLQGGEVGGPDSGNLKGGMTNCTLPHR--SLDIQHTTLYSNNSTANKSSVNSMDQPALQGSSRLSPSTDSSSNLTNVKLEVKKSPL---SSILFSALDSDTRITALLR--RQADIEIR-------ARRLQKRLQVVQAKQVERHLQHQLGGFLET---------------------------------------------------------------------------TLSKLPNLESLRSRSQLMLTRKAEAALR-KAASESATSEGLSNFLKS--------------------------DSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTRADPEQCHVPLKRRSEWRWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLIVLGEAPFPDHTTDLLS---------------LSSEVKTDHGRDKLIESVSQPSENHGILVS-NITESLST------------KSCGAPRPVNGVVNSLQPVLADQVPGDSSDAEEQLHKKQRLNLVSSS-DGTCVAARTRPVLTCKKRRLVRPSSIVP--------------------LSKKVHRN---VRSGCDVNPSCALCGSG-------------------------SVNTMPPEIHYEAPLLERLSQLDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPTKKFSLKHR-ATMPCSLSDP-----VRKDRHKLVNSFLTT---------------------------------------------------------------AMLKHHTDMSSP--SYLTATHHPPHSPLVRQLSTS---SDTSTPTSSGSQVAASTS-QPVRRRRGESSFDINN-------------------------------------------IVIPMSVAATTRVEKLQYK---------EILTPSWREVDVQS---------LKGSPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLGSANPSTPQPAS--PDVSSSHSLSEFSHGQSPRSPISPELHSAPLTPVARDS-LRHLASEDTRCSTPELGLDEQSVQP--WERRTFPLAYSPQAECEEQLDAQDTAARCTRRT------------------SGSKTGREAEVAPTSPPVVPLKSRHLAATVTAQRPAHR----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z3B3-1", "uniprot_id": "KANL1_HUMAN", "id": "Q7Z3B3-1", "name": "KAT8 regulatory NSL complex subunit 1", "aln": "MAAMAPALTDAAAEAHHIRFKLAPPSS--------------------TLSPGSAENNGNANILIAANGTKRKAIAAEDPSLDFRNNPT-------KEDLGKLQPL-----VASYLCSDVTSVPS----KESLKLQGVFSKQTVLKSHP---------------------LLSQSYELRAEL-----LGRQPVLEFSLENLRTMNTSGQTALPQAPVNGLAKKLTKSSTHSDHDNSTSLNG--------------------------------------GKRALTSSALHGGEMGGSESGDLKGGMTNCTLPHR--SLDVEHTTLYSNNSTANKSSVNSMEQPALQGSSRLSPGTDSSSNLGGVKLEGKKSPL---SSILFSALDSDTRITALLR--RQADIESR-------ARRLQKRLQVVQAKQVERHIQHQLGGFLEK---------------------------------------------------------------------------TLSKLPNLESLRPRSQLMLTRKAEAALR-KAASETTTSEGLSNFLKS--------------------------NSISEELERFTASGIANLRCSEQAFDSDVTDSSSGGESDIEEEELTRADPEQRHVPLRRRSEWKWAADRAAIVSRWNWLQAHVSDLEYRIRQQTDIYKQIRANKGLIVLGEVPPPEHTTDLFLP--------------LSSEVKTDHGTDKLIESVSQPLENHGAPIIGHISESLST------------KSCGALRPVNGVINTLQPVLADHIPGDSSDAEEQLHKKQRLNLVSSSSDGTCVAARTRPVLSCKKRRLVRPNSIVP--------------------LSKKVHRNST-IRPGCDVNPSCALCGSG-------------------------SINTMPPEIHYEAPLLERLSQLDSCVHPVLAFPDDVPTSLHFQSMLKSQWQNKPFDKIKPPKKLSLKHR-APMPGSLPDS-----ARKDRHKLVSSFLTTAKLSHHQTRPDRTHRQHLDDVGAVPMVERVTAPKAERLLNPPPPVHDPNHSKMRLRDHSSERSEVLKHHTDMSSS--SYLAATHHPPHSPLVRQLSTS---SDSPAPASSSSQVTASTSQQPVRRRRGESSFDINN-------------------------------------------IVIPMSVAATTRVEKLQYK---------EILTPSWREVDLQS---------LKGSPDEENEEIEDLSDAAFAALHAKCEEMERARWLWTTSVPPQRRGSRSYRSSDGRTTPQLGSANPSTPQPAS--PDVSSSHSLSEYSHGQSPRSPISPELHSAPLTPVARDT-PRHLASEDTRCSTPELGLDEQSVQP--WERRTFPLAHSPQAECEDQLDAQERAARCTRRT------------------SGSKTGRETEAAPTSPPIVPLKSRHLVAAATAQRPTHR----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TF07-1", "uniprot_id": "A0A8N7TF07_DANRE", "id": "A0A8N7TF07-1", "name": "", "aln": "MAAMAPALTDAPAEARHIRFKLASPSS--------------------TLSPGSTENNSNASNILISDSVSDSAGSHSNGKCHINSNDTHYHSVKDQDPLSKAPSLG---KLAPYLCSDVKPLPSSTKVKESLKLQGVLIKQSVLKSHG---------------------LLSGSIFPSAAAGGDFLLRKRHHLELTGGQLKSLVNGGGAGSTMVPVNGLSKKVAVPRAAVAEKGSVATVN--------------------------------------GDSNQPS---TNGEALLSVSSKSKSGQNGDVKPQQNSTPSIQGVSSHRELTALTESAEVKAEPGTPVGGLRIETNSNNDVSFENCPSSRSSSPVQDDSTIPTPNLEVLLRDRAKQSQQRQTDIESR-------LLRLRKRLQVVQAKQVERHFKQQLSGFLER---------------------------------------------------------------------------TLTPTS------SR------RGDPGAWRGSRTSVETHAHHLNRFLKG--------------------------GRVASELDSLHLSGTTHLHAAESQFDSDATESSSGGESDVEEDELARVDVEQCHIKLWRRAEGRFARERATIISHWTWLQAQISDLEYRIRQQVDIYRQLRTGKGPVELGDS---------------------------APSCKTETNENILTSTTSQ-----------NFSESQSR------------LTDASENIVS--ISSVS---------------------EMSDTCLLSLDGSSTSARTRPLVACRRRRLIHPNTIHN--------------------LNGKVQRVCFSPLRVCEVNSSCVMCGS--------------------------ARSLLKADSPYDRPLLERVAHHDRSVHPVLSMQSDVAFSVQLQKVLRTHWQTRPFDRIKPLKKIALKHKLSTTPPSSSSPSSSSFLSKHKFRLSNSHAAAVRFARHKSRSERFHRLPVENISCVPKPETLTPCRTGR-------VLDRSQSRKRVREPSLDRADLAPKVVMDAGSPCPSLSGLHSTNTSPLTRQLSLP---IESSTPLGSN---------VPIRRRRGESPFDINN-------------------------------------------IVIPMSVAATTRVEKLQYK---------EILTPRWREVDTLA---------QPLSEEDNNIQVEDLSDAVFAKLHQLCEDQERSRWRWTALAPAKRRGSRSYKSLDGRTTPSLIGTNPSTPQPSS--PDTSQFQILQDYGPVPSP----------SPLSPASPDTPHRLMYSEDTCGSTSDCTLEEKTVLP--WDLRSFPLPEDPIVEPEPEQDELSFSA-------------------------GLRVSVESESDASSP--------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E2QD16-1", "uniprot_id": "E2QD16_DROME", "id": "E2QD16-1", "name": "", "aln": "---MAPALTAEPLSPKEKLTSTASPSARSSSESGGVGCAVGLVKKPATPTPATATTRITRSSAAAASVTASPHLQQQRSSLAINNKRKSGNAKASNEPMGLSTAPTPHSTTSPNPSTDTAAASTSAVEHNNNDSNSTSAGNSTSADNSSTPKDNSTAQLLADLTINFEETISAEICLRKTLP-DVSLGKEPVPPASVLAVATSSTSAGSALSLSAVDEVTKIEIDNIEERLSQLDGNATGRPEEHVAPPSVPVPVQEAPNTPTRPQAPPSAHLESPQPARTQQQSIQQMTPQSTTSSNNFLKDGAAGAVLEDQDIEEVLKALKTFDGGHVNPDTICEFFDEVWEEAAPAAPLPPAPPENVVDVPGAKPSCSGILVSGSNISQPNVIIKQEQRPWQESHAELEQQQHVISRRIEFLLRRMRKLQARAMCRHASEEVVGIMEWSARSSHKAPVPARSSTLTEQEATVLSIVSGRPSSTFWEEQNKHPLPASQMSNVIRHIATAAKHQQICHSASGSSATLAPSSSWYNSCNSSALPMKRPRKNQLDASVATGATPTAPAPGAVTSRQAAGTTGSATGSNTPRADDIVPGYDTYVTNELTHVSGLLHTELREVQNAIDSDATESSSGGES--ADEMVTYNNNQQLSLPITRRAVWRYSRDRAAIALRWSWLCSQLTDLEMKIRQHSDLYMDLTQSKGEIQLESTAKTSPSLAQPANGIKEEPGSDYLCSRARPLVLSEFRKRKLFQTTNMHTISKKAARPSNIKCGCQWPQVPCTLCTGRTDPTAPRDLVETMMPQNRVALLDAGYHPVLSFASDVSQSVHLEAVARQPDWQYRVMRSQPKAIVKAMWKAERETIASGGVGGQGGSRRSGDAAKRRYIRRKERNNNSNKEAGSGAKAAAVAAGGAGGNGSSSVGGGDSGNGTGTATTSSSTTPTTTPLVANTAARGKRQPQHPTGANSSSSLWPDSRQRQRQRHHSPSSTSISALSGAKKARKSATNSSSSNSTQQQQNHHGTKINNHHLNGYGDQWGEQSRSRRNSSPSNSHKNERTSERRVRPIYDINNIVIPYSMLAQSKMEIIPYKEIPIPKWRIVDSDNDKGKHSSDESMERKLSNGCVASKSEELAKQQLPPPPDQDQEQPALQPPKVNGLKENQAVKHNNNNNTNNNNNKNGLVNGNAKKDELKAAEDHDTQSKEDDDPKEKVVKPKLNGNLIKNPIDKTAETQDKIAQPAPEPPLPKRPKLETPTSNEVTKANGQLVQQQLESRESEEEPQHVDEDLSDEAFIMRHQRALLEERRRFETFLKFPWSTRSRANRRVDSRAESSGANTPDPASPAPHLGGPGHDNESIPSPLAYPLDAFNESGELLTGGQARQARRRTTSSKLKDQLERRSTTPDLRESYTVMPSPFEPLNFPLSDEVYQRLLAETYAPPRSMTVSKRAKSKSISSNCDGGNTFTGGSGSRRSSKCKIKPNGQLNGQLNGHPAAAKLNGIDAANEGGISEPEEEEMLLEDEDDDYPKHHLAPLDDEEPSTPDVEHELYDSAIDAYLADPEALEEDMGEDPFEDDDPNDPEWKTRTEGVRSRRI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****** . ..:. . *.**: * :*.:: .. . . :. . . . :..: . :: :. . :. .:*. . .: ::. . :.. ::. .: :* . * :. : : : ... :. . .*: ::* . . . . * : . .. *.* . . .: : . . . .: : .. . .. . ... * . : : ::::* : * :*:: :**: : ** ..:: *::* **: . * . :: : : :.. ::.** . :.*: :. :***.*:******* :: :: : :* : : **: ::: :**:* :*.** ::::*** :***: *:* :: .** : * . . :: * .:.. ::. . . . .. *. : : . * *::* : . .:* : * :. . .:.:.. .*. : . . :* .: .:. :: * : : : . .:. * :* : : : . . . :. .. : . . . . *.:* . : * . .:::...:.. : ** * *:. :* *: : * :: ** .** * :: : ***** .* * . ** *: * . *. . : . :. .:*::* * *. .. . . .. . . : : .: **. :. :* * :: .***. . . : : * : . : : ... ", "identical_positions": 117, "similar_positions": 311, "identity": "7.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121219-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PEV3-1", "uniprot_id": "WIPF2_MOUSE", "id": "Q6PEV3-1", "name": "WAS/WASL-interacting protein family member 2", "aln": "MPIPPPPPPPPGPPPPPTFNQANTEQPKLSRDEQRNRGALLQDICKGTKLKKVTNVNDRSAPVIEKPRGSSGGYGPGA-------------------AALQPKGGLFQGGVPKLRPVGAKDASEAPAGKPALQVPSSRAAAPR-PPGSAASGRPHDDTDSNRASLPELPRMQRPSLPDLSRPNTASGTGMKHSSSAPPPPPPGRRANAPPTPLPLHSNKAQAYNREKPLPPT---PGQRLHPGREGHPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPG--PVRGLAPPPPTSATPSLLSNRPPPPAREPPSRGAAPPPPPPMIRNGARDAPPPPPPYR---MHGSEPPSRGKPPPPPS--RTPAGPPPPPPPPLRNGHRDSITTVRSFLDDFESKYSFHPVEDFPAPEEYKHLQRVYPSK-TNRAARGAPPLPPILR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TF74-1", "uniprot_id": "WIPF2_HUMAN", "id": "Q8TF74-1", "name": "WAS/WASL-interacting protein family member 2", "aln": "MPIPPPPPPPPGPPPPPTFHQANTEQPKLSRDEQRGRGALLQDICKGTKLKKVTNINDRSAPILEKPKGSSGGYGSGG-------------------AALQPKGGLFQGGVLKLRPVGAKDGSENLAGKPALQIPSSRAAAPR-PPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPT---PGQRLHPGREGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPG--PVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRNGARDAPPPPPPYR---MHGSEPPSRGKPPPPPS--RTPAGPPPPPPPPLRNGHRDSITTVRSFLDDFESKYSFHPVEDFPAPEEYKHFQRIYPSK-TNRAARGAPPLPPILR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6J1-1", "uniprot_id": "A0ACD6B6J1_DANRE", "id": "A0ACD6B6J1-1", "name": "", "aln": "MPIPPPPPPP-GPPPPPTFSQANTTAPKLNRDEAKGRGALLSDICKGAKLKKTTGVNDRSAPVIEKAGGRSGGGGGGGGGGSSGGGGGGGGGGFGGSSGPKAMGGLFSGGVPKLRPVGD-----SSVGRSALRPPGSRPAVPRGLSNSEVDGSSRG--DGSRTSPPEQQRNHRPSLPDVSKPSVPSSSSKPTNSAPPPPPPFNRAGNRGPSSAQQGSGQSRDKPFPPPPPPVSKGPPPPPSPAREGTPRHPPLSSRSSSS---SSISSGNAPPPPPPYRQPP-AANG------DPAPELPQRRNSLNRRGHGNANARSQAPPPPP---PSQQNRRPPPPARDPVGRSTAPQVPPPTSRNGIRETPPPPPPYRGGPQTSSEPPSRSKAPPLSSSGRQSSGHAPPPPPPLRNGHTSSAS--RSFADDFESKYDFHPIEDFPPPEEYRNFPKSYPSHNHNNRVRGAPPAPPVGGR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "********** ******** **** ***.*** :.*****.*****:****.*.:******::**. * *** * *. :. :. ****.*** ****** .*:.**: *.**.*.** . * ..* .:. *..*:* ** * :******:*:*...*.:. .*:.***** .* .* *:. *.:: * **. * *.*** * **:.. .*. :. *. . .********** ..** :.*******:***:*: * .*. *****. ** ..*******:* .*.:** *** *** *::******** .******.*.** .* * .:* .*********** .* : *** *******.***:****.****::: : ***: *. .***** **: ", "identical_positions": 233, "similar_positions": 102, "identity": "49.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121227-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZTZ1-1", "uniprot_id": "MSD1_HUMAN", "id": "Q6ZTZ1-1", "name": "Myb/SANT-like DNA-binding domain-containing protein 1", "aln": "MVRGAGPGPSLSALSHPTGASGMAAAEGPGYLVSPQAEKHRRARNWTDAEMRGLMLVWEEFFDELKQTKRNAKVYEKMASKLFEMTGERRLGEEIKIKITNMTFQYRKLKCMTDSESAPPDWPYYLAIDGILAKVPESCDGKLPDSQPPGPSTSQTEASLSPPAKSTPLYFPYNQCSYEGRFEDDRSDSSSSLLSLKFRSEERPVKKRKVQSCHLQKKQLRLLEAMVEEQRRLSRAVEETCREVRRVLDQQHILQVQSLQLQERMMSLLERIITKSSV------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BIL2-1", "uniprot_id": "MSD1_MOUSE", "id": "Q8BIL2-1", "name": "Myb/SANT-like DNA-binding domain-containing protein 1", "aln": "MVRWPGLRPCLSAILNPAGASNMAAAEVPGYLVSPQTEKHRRARNWTDAEMRGLMLVWEEFFDELKQTKRNAKVYEKMASKLFEMTGERRLGEEIKIKITNMTFQYRKLKCMTDSESIPPDWPYYLAIDRILAKVPESCEGKLPDGQQPGPSTSQTEASLSPSAKSTPLYLPYTQCSYEGHFEDDRSDSSSSLLSLKFRSEERPVKKRKMRSCHLQKKKLRLLEAMLEEQRRLSRAMEETCREVRRVLDQQNILQVQSLQLQERMMSLLEKIIAKSNV------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7EZ34-1", "uniprot_id": "E7EZ34_DANRE", "id": "E7EZ34-1", "name": "Myb/SANT-like DNA-binding domain-containing protein 1", "aln": "-----------------MASEDLCFS----YTVPGSNEKHRRARNWTDSEMKALVYIWEEYVTELKKAKRNAKIYETMAKQLYELTGEQRHREEIKMKITNMTFQFRKLKYTANGGSSTPDWPYYKSIERILSKVPDHGHMSPPNLSSSGPSTSQHDPAVPQSAPPSGFLPEYTGSSEERDMNDE-DDGLTDNSASSFETRSQPHKRRRLSHVSLRRKKLRVLDAMLKEQRRISHAVEEACHEVRRVMHQQNFLQVQSLQLQERMMNLLEKMIPAQSAPSWPNPASAKGLGTPTPE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:..:. : * *. . ***********:**:.*: :***:. ***::*****:**.**.:*:*:***:* ****:********:**** ::. * .****** :*: **:***: . . *: . .****** :.::. .* .: : *. .* * ::*: .*. :. : .*.:..:* *:*:: *::*:**:*:**::****:*:*:**:*:*****:.**::*************.***::*. ... ", "identical_positions": 123, "similar_positions": 91, "identity": "41.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121227-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P21462-1", "uniprot_id": "FPR1_HUMAN", "id": "P21462-1", "name": "N-formyl peptide receptor 1", "aln": "METNSSLPT--------NISGGTPAVSAGYL--FLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPG---KTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIK--SSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIR--ELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNS---TLPSAEVELQAK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P33766-1", "uniprot_id": "FPR1_MOUSE", "id": "P33766-1", "name": "N-formyl peptide receptor 1", "aln": "MDTNMSLLMNKSAVNLMNVSGSTQSVSAGYI--VLDVFSYLIFAVTFVLGVLGNGLVIWVAGFRMKHTVTTISYLNLAIADFCFTSTLPFYIASMVMGGHWPFGWFMCKFIYTVIDINLFGSVFLIALIALDRCICVLHPVWAQNHRTVSLAKKVIIVPWICAFLLTLPVIIRLTTVPNSRLGPGKTACTFDFSPWTKDPVEKRKVAVTMLTVRGIIRFIIGFSTPMSIVAICYGLITTKIHRQGLIK--SSRPLRVLSFVVAAFFLCWCPFQVVALISTIQVR--ERLKNMTPGIVTALKITSPLAFFNSCLNPMLYVFMGQDFRERLIHSLPASLERALTEDSAQTSDTGTNLGTNSTSLSENTLNAM-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FF45-1", "uniprot_id": "E7FF45_DANRE", "id": "E7FF45-1", "name": "", "aln": "MMDPFNFTESPPNHNSSEYDDDYVDYQNSELGKSLNIMSLIVYSLAFVLGVVGNGIVIWVTGFKMKRTVNTVWFLNLAVADFLFTAFLPLSVAYTAMGFHWPFGQFMCKFNSTLGFLNMFASVYILVVISVDRCVSVVRPIWAQNHRNVGRASAVSFGVWLFALLLSSPYFVFKDTAQDNR-DPKIINCFNNFAFSDADTQEVEDLRMLRHRAMIITRFIIGFVVPFVIIVSCYAVIIHRLQRNRSMSGKTGRPFRIIAAVITAFFLCWAPYHILVLIEMVNHMSTEYSPTLQHVITVGIPIVTSLAFLNSCLNPLLYVFMGQDFKDKVRKSILKVLETAFTEEVSRT-NTWTNS-MTTIRNKENGSKSFSDAEV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .: : ... . . : *:::: ::::::*****:***:****:**:*.:**.*: :****:*** **: **: :. .** ***** *:*** *: :*:*.**:::.:*::***:.*::*:*:****.*. *. * : *: *:**: * :: *. . . * :*: *. * .: : . * ****** .*: *:. .*.:* ::::: :. :.**:*::: * :******.*::::.** :. * : * .: :.:.***:******:*********:::: ::: ** *:**: ::* :* ** : * :: ", "identical_positions": 125, "similar_positions": 124, "identity": "33.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130103-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ERE8-1", "uniprot_id": "TLRN1_MOUSE", "id": "Q9ERE8-1", "name": "Talin rod domain-containing protein 1", "aln": "MASGSAGKPTGEAASPAPGSAVGGASSQPRKRLVSICDHCKGKMQLVADLLLLSSEARPVLFEGPASPGAGAESFEQCRDTIIARTKGLSILTHDVQSQLNMGRFGEAGDSLVELGDLVVSLTECSAHAAYLAAVATPGAQPAQPGLVDRYRVTRCRHEVEQGCAVLRATPLADMTPQLLLEVSQGLSRNLKFLTDACALASDKSRDRFSREQFKLGVKCMSTSASALLACVREVKAAPSELARSRCALFSGPLVQAVSALVGFATEPQFLGRAAAVSTEGKAVQTAILGGAMSVVSACVLLTQCLRDLAQHPDGSAKMSDHRERLRNSACAVSEGCTLLSQALRERSSPRTLPPVNSNSVN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1K6-1", "uniprot_id": "TLRN1_HUMAN", "id": "Q9H1K6-1", "name": "Talin rod domain-containing protein 1", "aln": "MASGSAGKPTGEAASPAPASAIGGASSQPRKRLVSVCDHCKGKMQLVADLLLLSSEARPVLFEGPASSGAGAESFEQCRDTIIARTKGLSILTHDVQSQLNMGRFGEAGDSLVELGDLVVSLTECSAHAAYLAAVATPGAQPAQPGLVDRYRVTRCRHEVEQGCAVLRATPLADMTPQLLLEVSQGLSRNLKFLTDACALASDKSRDRFSREQFKLGVKCMSTSASALLACVREVKVAPSELARSRCALFSGPLVQAVSALVGFATEPQFLGRAAAVSAEGKAVQTAILGGAMSVVSACVLLTQCLRDLAQHPDGGAKMSDHRERLRNSACAVSEGCTLLSQALRERSSPRTLPPVNSNSVN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA53EER7-1", "uniprot_id": "A0AA53EER7_DANRE", "id": "A0AA53EER7-1", "name": "", "aln": "MASSGSGKSD----SEVPTNILSGSLQQ-RKRLLSVCDACKSKMQLVADLLLLSSETRPVVNT---EGQPVAETFEKCRDTVIARTKELSIIVHDIQSQLNMGKFLEVGDRLVEMGDLVVSLTEYSAHAAYLAAAEIPGSQAAVSGLVDRYKVTRCRHEVEQTCNILRLTAVGDLTPPLLLEVSQNILKNLTMLTDASSLASDKSKDKFAKEQFKASVKCMSTSATALLACVRELKACPSELTRNRCVLFSGPLIQAVHALVGFATEPQFLGKAASITPDGKGVQTAVLGGAMSVVSACVLLTQGLRDISQHPESSQQMPVYRERLRNSACAVSDGCTLLSQALRERSSPRTLPPVNSHSVN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***..:**. * .* . :.*: .* ****:*:** **.**************:***: . . **:**:****:***** ***:.**:*******:* *.** ***:********* *********. **:*.* .******:********** * :** *.:.*:** *******.: :**.:****.:******:*:*::**** .********:********:*..****:*.**.******:*** *************:**:::.:**.****:**************** ***::***:.. :*. :************:***********************:***", "identical_positions": 252, "similar_positions": 74, "identity": "69.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130103-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AF93-1", "uniprot_id": "A0A8I6AF93_RAT", "id": "A0A8I6AF93-1", "name": "Pro-interleukin-16", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGLAPWGQKCICKGQVQQLGCGCPVLPAGGGHHQYALWHIHRRTPLLGCQGTAPPPCCSWHLLPGQANRTHAAAAKPSSSTTHRPRPGEQERKKRGLTS---SLRMEPHSHSGKSRKSTKFRSISRS--LILCNAKTSDDSS-------------------------------SPDEKYP-DPFETSLCQD-------------KEGFFHSSMQLADTSEAGLSNIPDLALASEAAQLQAAGSDRGKHCRKMFFLKESS---------TTSSKEKAGKSEAQ----SSNFLFP--------------------KACHQRTRSNSTSVNPYSAREMDFPMTKKSAAP--TDRQPYSLCSNRKSLSQQLDYP---VSGTARPTRSLSTAQLGQLSGGLQASVISN-------------------------------------------IVLMKGQAKGLG----------------FSIVGGKDSIYGPIGIYVK-----------------SIFAGGAAAADGRLQEGDEILELNGESIAG-------------------------------------------------------------------------------------------------------------------LTHQDALQKFKQAKKG-------------------------------------------LLTLTVRTRLTTPPSLCSH---------------------------------------------------------------------------LSPPLCRSLSSSTCGAQDSSPFSLESPASPASTAKPNYRIMVEVSLKKEAG-VGLGIGLCSIPYFQCISG--------------------VFIHTLSPGSVAHLDGRLRCGDEIVEINDSPVHCMTLNEVYTILSHCDPGPVPIIVSRHPDPQVSEQQLK--------------EAVAQAVEGVKFGKERHQWSLEG----VKRLESSWHGRPTLEKEREK-HSAPPHRRAQKIMVRSSSDSSYMSGSPGGSP-----------CSAGAELQPSEGEGSTHSP-SLPPGEEQEPCPGVPSRPH---QESPP-LSESLERDSHPPLKLKNSFEILVRKPTSTKPKPPPRKYFKNDSEPQKKLEEKEKVTDPSGHTLPTCSQETRELLP---------------------LLL-QEDTAGRTLCTAACCPGPAASTQTSSSTEGEP-RRSASPETPAS-PGKHPLLKRQARMDYSFDSTTEDPWVRISDCIKN--LFSPIMSENHSHMPLQPNASLGEEDGTQGHPEGGLSKMDTANGAPRIFKSADGSTVKKGPPVAPKPAWFRQSLKGLRNRVPETRRAPEVASAIQTTPVSRDASGPQSQASSSS--IRQRISSFENFGSSQLPDRGVQRLS----------------------------------------------------------LQPTSGETTRLPGKQDEGRFSGLPAQGTKVT-----AKHRQTEVEPPSTTFP----------------------NSSEVGDPDMSESPPPGQRPNPKALSP--DPLLRLLTTQ----TEDTQGPGFKMPSQRARSFPLTRTQS-----YETKLLDEKSSKLYSISSQLSSAVMKSLLCLPSSASCGQITCIPKERVSPKS-PCNNSAAAEGFGEAVASDT---GFSLNLSELREYSEGLTEPGETEDRN------HCSSQAGQSVISLLSAEELKKLIEEVRVLDEATLKQLDSIHVTVLHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGATHNDALAILRQARDPRQAVIVTR---------------------------------KAIVEAAHDLNSSTDSAASASVASGISVES--------------------------------------------------------------------VEATVCTVTLEKTSAGLGFSLEGGKGSLHGDKPLTINRIFKG--TEQGDAVQPGDEILQLAGTAVQGLTRFEAWNVIKALPDGPVTVVIRRNGLEGKQTTASADL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54824-1", "uniprot_id": "IL16_MOUSE", "id": "O54824-1", "name": "Pro-interleukin-16", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPHGHSGKSRKSTKFRSISRS--LILCNAKTSDDGS-------------------------------SPDEKYP-DPFETSLCQG-------------KEGFFHSSMQLADTFEAGLSNIPDLALASDSAQLAAAGSDRGKHCRKMFFMKESS---------STSSKEKSGKPEAQ----SSSFLFP--------------------KACHQRTRSNSTSVNPYSAGEIDFPMTKKSAAP--TDRQPYSLCSNRKSLSQQLDYP---ILGTARPTRSLSTAQLGQLSGGLQASVISN-------------------------------------------IVLMKGQAKGLG----------------FSIVGGKDSIYGPIGIYVK-----------------SIFAGGAAAADGRLQEGDEILELNGESMAG-------------------------------------------------------------------------------------------------------------------LTHQDALQKFKQAKKG-------------------------------------------LLTLTVRTRLTTPPSLCSH---------------------------------------------------------------------------LSPPLCRSLSSSTCGAQDSSPFSLESPASPASTAKPNYRIMVEVSLKKEAG-VGLGIGLCSIPYFQCISG--------------------IFVHTLSPGSVAHLDGRLRCGDEIVEINDSPVHCLTLNEVYTILSHCDPGPVPIIVSRHPDPQVSEQQLK--------------EAVAQAVEGVKFGKDRHQWSLEG----VKRLESSWHGRPTLEKEREK-HSAPPHRRAQKIMVRSSSDSSYMSGSPGGSP-----------CSAGAEPQPSEREGSTHSP-SLSPGEEQEPCPGVPSRPQ---QESPP-LPESLERESHPPLRLKKSFEILVRKPTSSKPKPPPRKYFKNDSEPQKKLEEKEKVTDPSGHTLPTCSQETRELLP---------------------LLL-QEDTAGRAPCTAACCPGPAASTQTSSSTEGES-RRSASPETPAS-PGKHPLLKRQARMDYSFDITAEDPWVRISDCIKN--LFSPIMSENHSHTPLQPNTSLGEEDGTQGCPEGGLSKMDAANGAPRVYKSADGSTVKKGPPVAPKPAWFRQSLKGLRNRAPDPRRPPEVASAIQPTPVSRDPPGPQPQASSS---IRQRISSFENFGSSQLPDRGVQRLS----------------------------------------------------------LQPSSGETTKFPGKQDGGRFSGLLGQGATVT-----AKHRQTEVESMSTTFP----------------------NSSEVRDPGLPESPPPGQRPSTKALSP--DPLLRLLTTQ----SEDTQGPGLKMPSQRARSFPLTRTQS-----CETKLLDEKASKLYSISSQLSSAVMKSLLCLPSSVSCGQITCIPKERVSPKS-PCNNSSAAEGFGEAMASDT---GFSLNLSELREYSEGLTEPGETEDRN------HCSSQAGQSVISLLSAEELEKLIEEVRVLDEATLKQLDSIHVTILHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGATHNDALAILRQARDPRQAVIVTR---------------------------------RTTVEATHDLNSSTDSAASASAASDISVES--------------------------------------------------------------------KEATVCTVTLEKTSAGLGFSLEGGKGSLHGDKPLTINRIFKG--TEQGEMVQPGDEILQLAGTAVQGLTRFEAWNVIKALPDGPVTIVIRRTSLQCKQTTASADS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14005-1", "uniprot_id": "IL16_HUMAN", "id": "Q14005-1", "name": "Pro-interleukin-16", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MESHSRAGKSRKSAKFRSISRS--LMLCNAKTSDDGS-------------------------------SPDEKYP-DPFEISLAQG-------------KEGIFHSSVQLADTSEAGPSSVPDLALASEAAQLQAAGNDRGKTCRRIFFMKESS---------TASSREKPGKLEAQ----SSNFLFP--------------------KACHQRARSNSTSVNPYCTREIDFPMTKKSAAP--TDRQPYSLCSNRKSLSQQLDCPAGKAAGTSRPTRSLSTAQLVQPSGGLQASVISN-------------------------------------------IVLMKGQAKGLG----------------FSIVGGKDSIYGPIGIYVK-----------------TIFAGGAAAADGRLQEGDEILELNGESMAG-------------------------------------------------------------------------------------------------------------------LTHQDALQKFKQAKKG-------------------------------------------LLTLTVRTRLTAPPSLCSH---------------------------------------------------------------------------LSPPLCRSLSSSTCITKDSSSFALESPSAPISTAKPNYRIMVEVSLQKEAG-VGLGIGLCSVPYFQCISG--------------------IFVHTLSPGSVAHLDGRLRCGDEIVEISDSPVHCLTLNEVYTILSHCDPGPVPIIVSRHPDPQVSEQQLK--------------EAVAQAVENTKFGKERHQWSLEG----VKRLESSWHGRPTLEKEREK-NSAPPHRRAQKVMIRSSSDSSYMSGSPGGSP-----------GSGSAEKPSSDVDISTHSP-SLPLAREPVVLSIASSRLP---QESPP-LPES--RDSHPPLRLKKSFEILVRKPMSSKPKPPPRKYFKSDSDPQKSLEERENSSCSSGHTPPTCGQEARELLP---------------------LLLPQEDTAGRSPSASAGCPGPGIGPQTKSSTEGEPGWRRASPVTQTS-PIKHPLLKRQARMDYSFDTTAEDPWVRISDCIKN--LFSPIMSENHGHMPLQPNASLNEEEGTQGHPDGTPPKLDTANGTPKVYKSADSSTVKKGPPVAPKPAWFRQSLKGLRNRASDPRGLPDPALSTQPAPASREHLGSHIRASSSSSSIRQRISSFETFGSSQLPDKGAQRLS----------------------------------------------------------LQPSSGEAAKPLGKHEEGRFSGLLGRGAAPT-----LVPQQPEQ-VLSSGSP----------------------AASEARDPGVSESPPPGRQPNQKTLPPGPDPLLRLLSTQ----AEESQGPVLKMPSQRARSFPLTRSQS-----CETKLLDEKTSKLYSISSQVSSAVMKSLLCLPSSISCAQTPCIPKEGASPTS-SSNEDSAANGSAETSALDT---GFSLNLSELREYTEGLTEAKEDDDGD------HSSLQSGQSVISLLSSEELKKLIEEVKVLDEATLKQLDGIHVTILHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHHDALAILRQAREPRQAVIVTR---------------------------------KLTPEAMPDLNSSTDSAASASAASDVSVEST-------------------------------------------------------------------AEATVCTVTLEKMSAGLGFSLEGGKGSLHGDKPLTINRIFKGAASEQSETVQPGDEILQLGGTAMQGLTRFEAWNIIKALPDGPVTIVIRRKSLQSKETTAAGDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QCG1-1", "uniprot_id": "A0A8M9QCG1_DANRE", "id": "A0A8M9QCG1-1", "name": "Pro-interleukin-16", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLSFERPPPLAAMHAGREPPSVAIQPLRNTHPQRRRTKRMERGKAG--LSSKKLAVLSRSLLICSSSAHEDASSPEEKYREPWDVPLEDRRPDGTLMSRSVSVQTSYRGHEGPKRAMRRSFSIKETSFWRMCVATRDDALH-------------------------------TADRKLQNCDNEASVAQDLH-----------RETYIYFGERLAPFNGQVINEQPNPEPDLHKHKTTESRNTSSKAFTENRALFTNT---------TESQQLGYGYGEKEPMGNNNNLQMPSIKVSDDDVKNIDNEDQGCQEMSCKRSRSNSTSVHPYWIGDLETIIMKTPELFPCSAHNTAAFYGNRKSLSQQLEFPHSVPQAVVRPSRSLSSAHLVPSCSSVQAFIISN-------------------------------------------IVLMKGHGKGLG----------------FSIVGGRDSMYGPMGIYVK-----------------TIFPGGAAAADGRLQEGDEILELNGESLHG-------------------------------------------------------------------------------------------------------------------LTHEDALHKFKQVKKG-------------------------------------------LLTLVVRTSLRVGAVMGSHG--------------------------------------------------------------------------QASQLCRSRSLSSSTAISRVSADLGEYNCLNNPAKAQDRVMMEITLHKEFG-VGLGIGLCCVPSSGGCPG--------------------IYIHTLSPGSVAHMDGRLRCGDEIMEINETVVCNMTLNDVYTVLSQCSPGPVHIIISRHPDPKVSEQQLN--------------EAISQAVENSRLRKDRSQWSMDGCNSSLRRPESCCHSRQKCMRCVDRSTSQLTCRRTQKPMIRSCSEGAYSQRCCIPNS-----------TTAQSFLHTDHVSLTTNSETSLNNTLSQSSFTDDDYNIP---YKCPVNFNGKQTFDVNASSGLVNQPRKYYRQQQEVSSQE-ALNVSSGSSRDSPVKEEDLMLSQSNCQFFCSLYRALRKISR---------------------LLFKNEVVEHAELGTKASACIS--EPKSDSTHRGDRLHKDPECSSQVCGSSKRVGLRRQAHLEVSTDQP-LDPWVKLTDSPENQSYCSKTMSDHNGDSEVNGTASETTES-----------------------KSEQATSVKKGPPVAPKSARARQSMKSIRSGKPITEALRNQQDNRSHETGRTFGISSRAASSGGNLSIRQKISSFETFSSPDGSERPSWRMAPTASVPPTEKTTKTSSADYSNADRTRVNTSNLRNNDYCQSTPPISATTLPSEEHSTSLILESHPEVEKQSTSHDSETCKSIPVEEPTVDPTEEITTAVETEQELVSSAKSSVDTEHEPVSSAETEQEPVSSTKSSVETEPVTSAETKQEPVSSEKDLPSVTHVPRRSSSSKEA-PGEKAEEAGTHAVSLRTRSLPLSPSSDGP---ISSGLEGESLGIILSFSNQVSSALMRSMQSLPQSPCIRLGNPWSAPPGSPLHNPIEEDSAAENPHASTALENNEKGFSVSLAELRERTIERGEECKTDDWKPEQALTSASAACAQSMLSVLPQPEIQRMIQEVKDLDEDTLRQLEDIHVVILHKEEGAGLGFSIAGGIDLENKATTVHRVFPSGLAAQEGTIEKGDEVLSINGQTLKNVTHSDATAILRQSRTLKQAVVVVS---------------------------------KNKDAEGKSAN-ANESSCSGGAESSIAGDD---------------------------------------------------------------------GGEVVTFELEKNAGGVGFSLEGGKGSISGDRPLAVNRIFTGSDAEQK-GLKSGDEVLQIQDSSLQGLTRFEAWTLIKNLNDGPFTLIVKRR--RCEQS------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUE8-1", "uniprot_id": "Q9VUE8_DROME", "id": "Q9VUE8-1", "name": "", "aln": "MASTPKANGTTAKTATINDDYITVVEVDDPTSNPKDRLKKLVKRQSSVAEDSSFITVLTINEMELLQQRKKEEDVGSGSSPTMEEQIENVTVFRLPGERLGFGLKFQGGTRSTELVQKLYIQSCAADSPASKVSTSWGNLREGDEIVSIDGRDVRELTRIDCVRGLKDNVAIKLVVRNGHGQKPPSEEDPQQQEHLSITLNAQPPPPPPVPPRKLVRRQNSKENQAQLLIEKPLTPPPDAEYYLNLLTESIKAGSESDDTASTISTVIDKFSVGSNYSSDSSLNGHELAKVLQPFTLLEQEFLPLEQPLGHPKLLIPGNNYENVEFKTEKVNVYENVELRSPETTPTPKPRVQLATVEPKKRSIIPMPRKIPTPTKLPIEVTPPRVPILEEPKTPTNNKVDSPKTPTNELKESPISATKIPKAKFSRAKTEGEIKLHLPAPKQQSPQSKSRIPIVSTPTAQKTVPKPVSPTMNGTPLSSNIPRLLQKQKSETDLKLNLYRSKSKESSPRPPLQRANSAEAPERTFIPVLLNGNSKSSNSLESVSSIGSSSSGNSVRSPKGPKPKPPERVQSLQKTQIPKLQALPTTPPQQIPKLSMQTFKQSPPTPRSTPVGTPSPTSNREIRFKIQTYESKTQDEDKLPSLFDLVHSQENDKDKDRDSDSLKTHNSITALLAAAAAEAADLSRESPPPLVVGKCMKIVDDTNTTTCYTSSSSGEEDEDDLDASNREYICEDGEKLGPPELINGPGPSEAYFNMFWHSNMLPTIGEVEEEFSSLEPQSLTNGNLVKSEESKKLPKMEVNAGGLAQLTDDKIADHDASATRADTRDEVTTNQTQEISSSSSSSVKSQKTTTTTRVTTTKTSSSSSSSSCSSTVIPDVAFKLQPYEERDDILSEPITTIHEERRVLSEQKTLSESRTRDALTGEEQLVTSANSKSSSARFKKISSNDNLLDLGDEQDMQEQPLTATITQESSLRERLECPQDNQSIDRGTLTLSERGKQLSEKEGLTTYTECETSEKESYLEGQQVLNGKGGFVSQDENSDQPTYEREVSETLTIVNDGEKQVTKKLEQNKEIAGKKGAKLLKKTDEERRLEQEAQKLIESYQKVKKEAEKLYKLELADDDQGFDLSAFEQAEEEDKPEVSEEIKEVKDSQPVKVDIQIEEEVKTPNQVIGEVKVEDVNKEIKETVQVSQQEIKKEVKVSHQETKETFKSEEKDESNELKIVKEEVKVTHQDLREQIQEIEAVKVVHKEVKVIKESAKVTTTTSHKQATKEVIISKEDHKNDSALPAVSTTKVEIISPPLEDDLGYVLHKHIIFPQEKVKTAPTPLPKPKPKPPVPTNKPKMPVNLTKPKSAPPPVPSKRSELSGSGGKPTPTQRRGSLETAQPPKPLERIIVGVEQRDEPEKPQPIINLASVDLPNVAPNSKQATVETTPVVEMPPDELQFESHQLPDDGEKEKDLHQESNDLLSGSSSSSVTTPITTPILVSATSSMDSVQSVIEVVNGMPIISNQQTDDDDIDEVAAYDDGMHLEAEGTKDVRPVQEVTTLTLDREHESDLGTLSNHHSNISSISGINASSNIPAATLISSSIKKTSTEAATTKPAAPQIPGKMELLSSNTGTTTTTTTATHHLHQATTTKQLLVQDYLSYASPPTYSRLPPDGHEFPPNFSEPLIMHSHPLKVTTELSYEIQKGGKDESSAPPLPKTGPPATVPRKVYRQDLVINVEPAPSLTRDYQRSLSGGTPRKPSDWRKDEKSEKSVRDKIAMFSSNNELDAIPPAPATAPISSSFTRKPLNRSSENLLDSCSSSSAPSLKTRAMSVENLNDVQRQYQLAKQLPQLHVADSMYSLNTATPTPSYASLPRRSHGGSYSSGVERRISFSGEGGDAANRKAAITNILEQRRRSLSKLRGLVIPERPQLLEPILDLPEIKSQVKAASGEDSTDSGLGESHRSTVNRNCQLGAGGAANNYRSILNTNQRRPLEQQLSQPPAKPPRTSLTPLQPRSMMIPPPPPPLDQESDTDSVFSHTARVATPPEKFALTRTLSSETNTSIASSNTSTLTSGSSAGSQASCSSLGSTPAVDLTRRVLKSQVINGEAVALSSRKSILASAKCRSAKSRGQEEDNDSTDGEACSLANRRMKPISSYKLQQQQIQLGKQLVVDKLINVAAYVELTSDTDDSSRRSDTPAKISAMFIDEERKASFKGDPNQQAKVKVEQVKPMVLPMLLPSAKREPLKQQTTAELREKFERSAAAQAQTQNHSPVIHKVTQKPHHERFSSLDSLASSSSGVSSTTQNVSTTQETATEFGSFSSLGSNQSLITAQDVQQIVEEA----DPPLKTPEAFIIVLQRENPESSIGITLAGGSDYEAKEITIHKILSNTPAAKDGRLKKGDRILAVNGMSMRGLTHRESISVLKTPRPEVVLVVTRSESLVVKALTKKRSSLGSLSSLNEKPTELDYERKRNYHKASRSLDLDLDLVSNEAGESPVATTPSTGSVSPPQPASLHDEDAEATIAGIRARRQLSRGDAAKLSTSELLERAAEARNAIAAEIRAQAEDAAASGGGARCVEIVKDSCGLGFSIEGGFDSPLGNRPLIVKKVFMGGAAQKTNQVRNGDEILSINGASTSRMTRVDAWNYMKQLPLGPVKICFA---------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . .* : . . * *.. . :.:. : . .. : . . . .: . : .: . :.: . ... : *.*:* . :: : . :: :*: **:* . . ..* :: ... : ** : :. :.* *. * : *:: : * *: : :*. .* . :*::..** :* .: ::*::: ..**. :*. :* .. . : *: .. : . * : . . ...*. *::: : :.* *.*..: .. . * *. .. . * : ...* : ..: * . : . : . . :* : * :*:** . . ::..:. : :: ::: * *.. . : . . .. : ::.::.: . . . : : . . :* : * . . : * : . :. : : . .. : : .: . : . :: .: : * . . .:. . .: . : . : :.. :: . : . * ::::*. . : * : : . :. : * * *: . :.: .: . . . . : .. .: * ::. :: : : :. . . . . : . * :. . .. * . : : : . * * . * . : .: : .: .*:.. :: : .. . : .: .. . :. .* .* . : . : . * . * *::. :::::::*. : .*: : : :.: ::: :.:*:::*** * * * *:*:::.. *:::* ::**:.:*::** :::. ** :: ::*: .* *:. : . : : .. . * :: . . . : * : *:***:*** .* *::** ::::* * ::: :: ***:*.: .:: . :**.:**. :* * **..: . ", "identical_positions": 121, "similar_positions": 417, "identity": "4.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130103-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D110-1", "uniprot_id": "MTHFS_MOUSE", "id": "Q9D110-1", "name": "5-formyltetrahydrofolate cyclo-ligase", "aln": "MAAVTVNSAKRGLRAELKQRLRALSAEERLRQSLLLTQKVIAHNQYQNSKRISIFLSMQD-EVETEVIIKDIFKQGKICFIPRYQFQSNHMDMVRLTSSEEIALLPKTS-------WNIHQPGEGD-VREEALSTGGLDLIFLPGLGFD-KDGNRLGRGKGYYDTYLKR-CVQHQEVKPYTMALAFKEQICP--QIPVDEHDMKVDEVLYEDSPAS--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "L7N466-1", "uniprot_id": "L7N466_MOUSE", "id": "L7N466-1", "name": "5-formyltetrahydrofolate cyclo-ligase", "aln": "MAAVTVNSAKRGLRAELKQRLRALSAEERLRQSLLLTQKVIAHNQYQNSKRISIFLSMQD-EVETEVIIKDIFKQGKICFIPQYQFQSNHMDMVRLTSPEEIALLPKTS-------WNIHQPGEGD-VREEALSTGGLDLIFLPGLGFD-KDGNRLGRGKGYYDTYLKR-CVQHQEVKPYTMALAFKEQICP--QIPVDEHDMKVDEVLYEDSPAS--------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LXC0-1", "uniprot_id": "A0ABK0LXC0_RAT", "id": "A0ABK0LXC0-1", "name": "5-formyltetrahydrofolate cyclo-ligase", "aln": "MAAVTVNSAKRGLRAELKQRLRALGAEERLRQSHLLTQKVIAHSQYQNSKRISIFLSMQD-EIETEEIIKDIFKQGKICFIPRYQFHSNHMDMVRLTAPEEVALLPKTS-------WNIHQPGEGD-VREEALSTGGLDLIFLPGLGFD-KDGNRLGRGKGYYDTYLKR-CVQHQKVKPYTLALAFREQICP--QIPVDEHDMKICHEDPNRTWNSGECSSAQRSYHITKSLWIASVKLEPTCGILSHMHIKTVRSHISVLWTVYNQTQIFSQKGVQKLPWVLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49914-1", "uniprot_id": "MTHFS_HUMAN", "id": "P49914-1", "name": "5-formyltetrahydrofolate cyclo-ligase", "aln": "MAAAAVSSAKRSLRGELKQRLRAMSAEERLRQSRVLSQKVIAHSEYQKSKRISIFLSMQD-EIETEEIIKDIFQRGKICFIPRYRFQSNHMDMVRIESPEEISLLPKTS-------WNIPQPGEGD-VREEALSTGGLDLIFMPGLGFD-KHGNRLGRGKGYYDAYLKR-CLQHQEVKPYTLALAFKEQICL--QVPVNENDMKVDEVLYEDSSTA--------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2L0J2-1", "uniprot_id": "A0A0G2L0J2_DANRE", "id": "A0A0G2L0J2-1", "name": "5-formyltetrahydrofolate cyclo-ligase", "aln": "MAALRA--AKQALRREIKSRVAAVSDQEKLRQSRVVSQKLFRHPKYLSSQRVAVFLNMHD-EVATEDILQDIFRRGKTCFIPRYFTKSSHMDMLRLKDMEDMETLPLTA-------WNIRQPGDDDKHREEALDTGGLDLILMPGLGFD-KSGNRLGRGKGFYDTYLER-CRTHPKGKPYTIALAFKEQICA--EIPVGEHDIVIDEVLHEDE-----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8MLS1-1", "uniprot_id": "Q8MLS1_DROME", "id": "Q8MLS1-1", "name": "5-formyltetrahydrofolate cyclo-ligase", "aln": "MAATIQNTLKVALRKRMKDALKGIDAEAIARQSQAVTAKVLQSEIFRQAQRVSIYLSTAS-ELDTTALLSEMFRLEKMVFVPTYE--GSRMKMVRLRGMEEYESLPLTK-------WNIKQPDFKEAREDAMTNGHGIDLFIVPGVAFT-RCGARMGHGMGYYDKFLKQHAEKYPHKKISLMALSLNEQIVSNEELPMESHDVRLHSVITEN------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40099-1", "uniprot_id": "FTHC_YEAST", "id": "P40099-1", "name": "5-formyltetrahydrofolate cyclo-ligase", "aln": "------MATKQLLRRQIKRVINALDYDIIAAESHTISQAVRSLIASANSRRVACYMSMDKGEVTTGEIIKNLFQDGQEVFLPRCTHTSESKHFKLREDHHPHLIFHRMSSLKMVRDLKPQGPYQLKEPEPHIEESDILDVVLVPGVAFDIKTGARMGHGAGYYDDFFQRYKILHEGQKPLLVGLCLMEQVAS--PIPLEKHDYSMDCIVCGDGSIHWFQ-----------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ** .:* : .:. : :* :: : .::*:: ::. . *: * ::.::*: : *:* .. .: . : : * . . . :*:.::**:.* : * *:*:* *:** :::: : * :.*.: **: :*: .:* : ", "identical_positions": 29, "similar_positions": 65, "identity": "10.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130103-9", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88664-1", "uniprot_id": "TAOK1_RAT", "id": "O88664-1", "name": "Serine/threonine-protein kinase TAO1", "aln": "MPSTNRAGSLKDPEIAELFFKEDPEKLFTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPTLQSNEWSDYFRNFVDSCLQKIPQDRPTSEELLKHMFVLRERPETVLIDLIQRTKDAVRELDNLQYRKMKKLLFQEAHNGPAVEAQEEEEEQDHGGGRTGTVNSVGSNQSIPSMSISASS-QSSSVNSLPDAS----DDKSELDMMEGDHTVMSNSSVIHLKPEEENYQEEGDPRTRASAPQSPPQVSRHKSHYRNR---------------------------------------------------------------------------------------------------------------EHFATIRTASLVTRQMQEHEQDSELREQMSGYKRMRRQHQKQLMTLENKLKAEMDEHRLRLDKDLETQRNNFAAEMEKLIKKHQASMEKEAKVMANEEKKFQQHIQAQQKKELNSFLESQKREYKLRKEQLKEELNENQSTPKKEKQEWLSKQKENIQHFQAEEEANLLRRQRQYLELECRRFKRRMLLGRHNLEQDLVREELNKRQTQKDLEHAMLLRQHESMQELEFRHLNTIQKMRCELIRLQHQTELTNQLEYNKRRERELRRKHVMEVRQQPKSLKSKELQIKKQFQDTCKIQTRQYKALRNHLLETTPKSEHKAVLKRLKEEQTRKLAILAEQYDHSINEMLSTQALRLDEAQEAECQVLKMQLQQELELLNAYQSKIKMQAEAQHDRELRELEQRVSLRRALLEQKIEEEMLALQNERTERIRSLLERQAREIEAFDSESMRLGFSNMVLSNLSPEAFSHSYPGASS----WSHNPTGGSGPHWG-----------HPMGG---TPQAWGHPMQG-GPQPWGHPSGPMQGVPRGSSIGVRNSPQALRRTASGGRTEQGMSRSTSVTSQISNGSHMSYT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5F2E8-1", "uniprot_id": "TAOK1_MOUSE", "id": "Q5F2E8-1", "name": "Serine/threonine-protein kinase TAO1", "aln": "MPSTNRAGSLKDPEIAELFFKEDPEKLFTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPTLQSNEWSDYFRNFVDSCLQKIPQDRPTSEELLKHMFVLRERPETVLIDLIQRTKDAVRELDNLQYRKMKKLLFQEAHNGPAVEAQEEEEEQDHGVGRTGTVNSVGSNQSIPSMSISASS-QSSSVNSLPDAS----DDKSELDMMEGDHTVMSNSSVIHLKPEEENYQEEGDPRTRASDPQSPPQVSRHKSHYRNR---------------------------------------------------------------------------------------------------------------EHFATIRTASLVTRQMQEHEQDSELREQMSGYKRMRRQHQKQLMTLENKLKAEMDEHRLRLDKDLETQRNNFAAEMEKLIKKHQAAMEKEAKVMANEEKKFQQHIQAQQKKELNSFLESQKREYKLRKEQLKEELNENQSTPKKEKQEWLSKQKENIQHFQAEEEANLLRRQRQYLELECRRFKRRMLLGRHNLEQDLVREELNKRQTQKDLEHAMLLRQHESMQELEFRHLNTIQKMRCELIRLQHQTELTNQLEYNKRRERELRRKHVMEVRQQPKSLKSKELQIKKQFQDTCKIQTRQYKALRNHLLETTPKSEHKAVLKRLKEEQTRKLAILAEQYDHSINEMLSTQALRLDEAQEAECQVLKMQLQQELELLNAYQSKIKMQAEAQHDRELRELEQRVSLRRALLEQKIEEEMLALQNERTERIRSLLERQAREIEAFDSESMRLGFSNMVLSNLSPEAFSHSYPGASS----WSHNPTGGPGPHWG-----------HPMGG---TPQAWGHPMQG-GPQPWGHPSGPMQGVPRGSSMGVRNSPQALRRTASGGRTEQGMSRSTSVTSQISNGSHMSYT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L7X3-1", "uniprot_id": "TAOK1_HUMAN", "id": "Q7L7X3-1", "name": "Serine/threonine-protein kinase TAO1", "aln": "MPSTNRAGSLKDPEIAELFFKEDPEKLFTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPTLQSNEWSDYFRNFVDSCLQKIPQDRPTSEELLKHIFVLRERPETVLIDLIQRTKDAVRELDNLQYRKMKKLLFQEAHNGPAVEAQEEEEEQDHGVGRTGTVNSVGSNQSIPSMSISASS-QSSSVNSLPDVS----DDKSELDMMEGDHTVMSNSSVIHLKPEEENYREEGDPRTRASDPQSPPQVSRHKSHYRNR---------------------------------------------------------------------------------------------------------------EHFATIRTASLVTRQMQEHEQDSELREQMSGYKRMRRQHQKQLMTLENKLKAEMDEHRLRLDKDLETQRNNFAAEMEKLIKKHQAAMEKEAKVMSNEEKKFQQHIQAQQKKELNSFLESQKREYKLRKEQLKEELNENQSTPKKEKQEWLSKQKENIQHFQAEEEANLLRRQRQYLELECRRFKRRMLLGRHNLEQDLVREELNKRQTQKDLEHAMLLRQHESMQELEFRHLNTIQKMRCELIRLQHQTELTNQLEYNKRRERELRRKHVMEVRQQPKSLKSKELQIKKQFQDTCKIQTRQYKALRNHLLETTPKSEHKAVLKRLKEEQTRKLAILAEQYDHSINEMLSTQALRLDEAQEAECQVLKMQLQQELELLNAYQSKIKMQAEAQHDRELRELEQRVSLRRALLEQKIEEEMLALQNERTERIRSLLERQAREIEAFDSESMRLGFSNMVLSNLSPEAFSHSYPGASG----WSHNPTGGPGPHWG-----------HPMGG---PPQAWGHPMQG-GPQPWGHPSGPMQGVPRGSSMGVRNSPQALRRTASGGRTEQGMSRSTSVTSQISNGSHMSYT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WGA8-1", "uniprot_id": "X1WGA8_DANRE", "id": "X1WGA8-1", "name": "non-specific serine/threonine protein kinase", "aln": "MPNAVRAGSLKDPDIADLFFKEDPERLFSDLREIGHGSFGAVYFARDVRTSEVVAIKKMSYSGKQSNEKWQDIIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLGSTSDLLEVHKKPLQEIEIAAITHGALQGLAYLHSHNMIHRDIKAGNILLTEPGQVKLADFGSASIASPANSFVGTPYWMAPEVILAMDEGQYDGKVDIWSLGITSIELAERKPPLFNMNAMSALYHIAQNESPSLQSSEWTDYFRNFVDSCLQKLPQDRPHSEELLKHAFVQRERPESVLIDLIQRTKDAVRELDNLQSRKMKKILFQEAHNGPAVEVPDDEEEVEHSVGRTGTVNSVGSNQSIPSMSISASS-QSSSVNSLPDATDATDDNKSEVDLMEKDQTIIPNSSIIHVKPEEESYQEETEVQKQPTEPQSPPAHTPRR-QYRNR---------------------------------------------------------------------------------------------------------------EHFATIRTASLVTRQIQEHEQDSEVREQMSGYKRMRRQHQKHLLALENKLKGEMDEHRLKLDKELENQRNSFAAEMDKLIKKHQGTMEKDAKTFANDEKKFLQHIQSQQKKELNSFLESQKREYKLRKEQLKEELNENQSTPKKEKQEWLSKQKENIQHFQAEEEANLLRRQRQYLELECRRFKRRILIARHNVEQDLMREELNKRQTQKDLEHAMLLRHHESMQELEFRHLGTIQKMRAEQIRLQHQTELTNQLEYNKRRERELRRKHVMEVRQQPKSLKSKELQIKKQFQDACKIQTRQYKALRNHLLESTPKPEHKTMLKRLKEEQTRKLAILAEQYDHTINNMLSTQALRLDEAQEAECQVLRMQLQQELELLNAYQSKIKMQTDAQQERERKELEQRVSLRRALLETKIEEEMLTLQNERTERIRSLLERQAREIEAFDSESMRLGFSNMVLANISPEGLSHSFPGAPASWMPHQHHSDGSQGTQWGSSTGSGGGHHYHPSQGGAQVQQAWGQAIPGSGLPPWGHSSSGPPGAMPKSSVGMRNSPQALRRTTSAGRTEQGMSRSTSITSQISNGSHLSYT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0KHQ5-1", "uniprot_id": "TAO_DROME", "id": "Q0KHQ5-1", "name": "Serine/threonine-protein kinase Tao", "aln": "MP-SARPGSLKDPEIADLFNKHDPEKIFEDLREIGHGSFGAVYYARCNLTREIVAIKKMSYTGKQSQEKWQDILKEIRFLRQLNHPNTIEYKGCYLRESTAWLVMEYCVGSASDIIEVHKKPLHEDEIAAICLGVLSGLSYLHSLGRIHRDIKAGNILLTDNGVVKLADFGSAAIKCPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPYFNMNAMSALYHIAQNESPTLPKNDWSDAFCSFVELCLKKMPAERPSSAKLLTHAYVTRPRSDTVLLELIARTKSAVRELDNLNYRKMKKILMVDTCETESAVGDTDDQQDDHAGGDSSKSNSITSEHSIHSVGVSAASSQSSSSNSIPAAAQ---NHHHIAAHHHQQAASAAVAAAMHHHHHPHQQPPPSWPSGQQGQPVPPGAVSRNSSRHRNRPPLPNIMHSMNNNVTPTNSASVVPAPAPAPVLPPPISVLPHLSAMGHVGGGGTGTGGSGGGSPASGGPLADRIQPVQPRYLTTPAAQAAVYAASSASSQQAISNAVNDHGPNNFATIRTTSIVTKQQKEHMQE-EMHEQMSGYKRMRREHQAHLVKLEEKCKVDMEAHKTALDKEYDTLLHNFTRDLDRLETKHQQDVERRAKQTSAAEKKLHKEITLKQENDRKVYDLNRKKEYKANKERWKRELSMDESTPKRQRDLTLQSQKDNLKQHEAQEEQRMLQAQKQYIELEMRKFKRKRMIMQHEHEDQQLRDELGKKEQQLQQAHAMLLKHHEKTQELEYRQQKSVHQLREEQINKQHDTELHNQKDYMDRIKKELVRKHAVELRQQPKSLKQKELQIRKQFRETCKTQTKQYKRYKAQVLQTTPKEQQKEVIKQLKEEKHRKLTLLGEQYEQSIADMFQSQSYKLDESQVIECQRTHEQLEYELEMLTAYQNKNKKQAQEQRDRERRELENRVSVRRGLLENKMDAELQQFNQERAERLRMKHEKHTKELEAFDNESIALGFSTLSLIEVSREAYAD-------------------------------------------------------------------EEGSLSGSMISLAHS---------------------NSSTSFPAGSL----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : *.******:**:** *.***::* **************:** * *:********:**** ******:**::**::::***:********** *********:**:**::*******:* ***** *.*.**:**** *************: * *********:: .******************************:******.********* ******************:* ..:*:* * .**: **:*:* :** * :**.* :* * *.::**::** ***.********: *****:*: :: : :. :::: :*. * :.. **: *::** *:.:**:* **** **:* .: :.: . : : . :: :* : . .. : * .* : . ::*** ::******:*:**:* :** *: *::***********:** :*: **:* * :*: *: ***: :. :.*: ::::* .*** :*: ** : ***: :.* :*::: : : .:*:*** .**: *.**. ::****:::: *..**:*:::.:*:** .:*: *:**:*** *:***: :: :*: *:: :*:**.*:: * : *****::**. ****:*: :::::* * *. **:*** ** :* .* ::** ***.:*:********.*****:***:::** **:*** : ::*::*** ::* ::*:****: ***::*.***:::* :*:.:*: :***:* *** : **: ***:*.***.* * *:: *::** :***:***:**.*** *:: *: :::**:**:* *::::*:****.**: ****.: * ::* *. :. * * :.: :* . ::.:. ** ", "identical_positions": 476, "similar_positions": 272, "identity": "41.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130109-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H3J6-1", "uniprot_id": "MTRFR_HUMAN", "id": "Q9H3J6-1", "name": "Mitochondrial translation release factor in rescue", "aln": "MS---TVGLFHFPTPLTRICPAPWGLRLWEKLTLLSPGIAVTPVQMAGKKDYPALLSLDENELEEQFVKG-HGPGGQATNKTSNCVVLKHIPSGIVVKCHQTRSVDQNRKLARKILQEKVDVFYNGENSPVHKEKREAAKKKQERKKRAKETLEKKKLLKELWESSKKVH---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80VP5-1", "uniprot_id": "MTRFR_MOUSE", "id": "Q80VP5-1", "name": "Mitochondrial translation release factor in rescue", "aln": "MSSRSTWALLRLPLPLIRICSGKWGLRLQEKPALLFPGMAASTVQVAGRKDYPALLPLNESELEEQFVKG-HGPGGQATNKTSNCVVLKHVPSGIVVKCHQTRSVDQNRKIARKVLQEKVDVFYNGENSPVHKEKLEAERRKRERKKRAKETLEKKKLLKELREASQNITEKKADADGIPRGFQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A5WUX7-1", "uniprot_id": "MTRFR_DANRE", "id": "A5WUX7-1", "name": "Mitochondrial translation release factor in rescue", "aln": "MT-------LFFSHRLFTVWRLKCGV-----MDIGWP----SVLPAAGKKYQIELPVVHEEELEEQFVRG-SGPGGQATNKTSNCVVLRHIPSGIVVKCHETRSVDLNRKRAREILREKLEVAYKGEESELLKMKKESMQKKQDKRRKVNENIEKKRRFKEMLNSKQEDDKST------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZAD7-1", "uniprot_id": "A1ZAD7_DROME", "id": "A1ZAD7-1", "name": "Prokaryotic-type class I peptide chain release factors domain-containing protein", "aln": "-----------MLRGLVRFLALPP-----------------TAVRCKSNLDYSRFPVLQESDIEETFMRG-SGPGGQAVNKTSNCVFLRHLPTNITVKCHTHRLASKNRVEARKLLLEKLDVHLNGEHSIAAQVKAQEQRKSTERRRRQEKLQEMKKSWQDRERTDGGTKSTDKE----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q05863-1", "uniprot_id": "YL281_YEAST", "id": "Q05863-1", "name": "Uncharacterized peptide chain release factor-like protein YLR281C, mitochondrial", "aln": "-----------MMRGASKRSISSAAV---------------LLIKKNKLPPRPKFTPEMEAQCTEKFLHGGRGPGGQKINKCNSKVQLRHEPTGIVVECQETRSREQNRKLARLKLARELAASYDTMPSREEALLQWHRQQKRSQRRRSVAKYEQREEAARVEKEEREARDREMVRELFRR----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * : * *::* ***** ** .. * *:* *:.*.*:*: * . ** ** * .:: . . * ::. .:::: * :. . . ", "identical_positions": 26, "similar_positions": 32, "identity": "14.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130114-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8JZU2-1", "uniprot_id": "TXTP_MOUSE", "id": "Q8JZU2-1", "name": "Tricarboxylate transport protein, mitochondrial", "aln": "MAAP-------RGPRALSAAAPGSGKPKLTHPG-KAILAGGLAGGIEICITFPTEYVKTQLQLDERANPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDA------QGRLDSRRGLLCGLGAGVAEAVVVVCPMETIKVKFIHDQTSSNPKY--------------------------RGFFHGVREIIREQGLKGTYQGLTATVLKQGSNQAIR---FFVMTSLRNWYQGDNHNKPMNPLITGVFGATAGAASVFGNTPLDVIKTRMQGLEAH-KYRNTLDCGLKILKNEGPKAFYKGTVPRLGRVCLDVAIVFIIYDEVVKLLNKVWKTD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32089-1", "uniprot_id": "TXTP_RAT", "id": "P32089-1", "name": "Tricarboxylate transport protein, mitochondrial", "aln": "MAAP-------RAPRALTAAAPGSGKAKLTHPG-KAILAGGLAGGIEICITFPTEYVKTQLQLDERANPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDA------QGRLDSRRGLLCGLGAGVAEAVVVVCPMETVKVKFIHDQTSSNPKY--------------------------RGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIR---FFVMTSLRNWYQGDNPNKPMNPLITGVFGAVAGAASVFGNTPLDVIKTRMQGLEAH-KYRNTLDCGVQILKNEGPKAFYKGTVPRLGRVCLDVAIVFVIYDEVVKLLNKVWKTD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53007-1", "uniprot_id": "TXTP_HUMAN", "id": "P53007-1", "name": "Tricarboxylate transport protein, mitochondrial", "aln": "MPAP-------RAPRALAAAAPASGKAKLTHPG-KAILAGGLAGGIEICITFPTEYVKTQLQLDERSHPPRYRGIGDCVRQTVRSHGVLGLYRGLSSLLYGSIPKAAVRFGMFEFLSNHMRDA------QGRLDSTRGLLCGLGAGVAEAVVVVCPMETIKVKFIHDQTSPNPKY--------------------------RGFFHGVREIVREQGLKGTYQGLTATVLKQGSNQAIR---FFVMTSLRNWYRGDNPNKPMNPLITGVFGAIAGAASVFGNTPLDVIKTRMQGLEAH-KYRNTWDCGLQILKKEGLKAFYKGTVPRLGRVCLDVAIVFVIYDEVVKLLNKVWKTD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R4U0-1", "uniprot_id": "TXTPB_DANRE", "id": "F1R4U0-1", "name": "Tricarboxylate transport protein B, mitochondrial", "aln": "MSGSPKFVSPFHRPHCLSAAAP-AGQAKLTHPG-KAILAGGIAGGIEICITFPTEYVKTQLQLDEKANPPRYKGIVDCVKQTVQGHGVKGLYRGLSSLLYGSIPKAAVRFGVFEFLSNQMRDE------SGKLDSTRGLICGLGAGVAEAVVVVCPMETVKVKFIHDQTSANPKY--------------------------RGFFHGVREIVRTQGLKGTYQGLTATVLKQGSNQAIR---FYVMTALRNWYKGDNPNKSINPVVTGLFGAVAGAASVFGNTPLDVIKTRMQGLEAH-KYKSTVDCAIKIMKYEGPAAFYKGTVPRLGRVCMDVAIVFIIYEEVVKVLNKVWKTD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KSQ0-1", "uniprot_id": "Q7KSQ0_DROME", "id": "Q7KSQ0-1", "name": "Citrate transport protein", "aln": "MDRSAFASLVSPYRRRPWMTEHGAAAADSGQVGLKGIVAGGITGGIEICITYPTEYVKTQLQLDEKGAAKKYNGIFDCVKKTVGERGFLGLYRGLSVLVYGSIPKSAARFGAFEFLKSNAVDS------RGQLSNSGKLLCGLGAGVCEAIVAVTPMETIKVKFINDQRSGNPKF--------------------------RGFAHGVGQIIKSEGISGIYKGLTPTILKQGSNQAIR---FFVLESLKDLYKGDDHTKPVPKLVVGVFGAIAGAASVFGNTPLDVVKTRMQGLEAS-KYKNTAHCAVEILKNEGPAAFYKGTVPRLGRVCLDVAITFMIYDSFMDLFNKVWV--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38152-1", "uniprot_id": "TXTP_YEAST", "id": "P38152-1", "name": "Tricarboxylate transport protein", "aln": "-------------------MSSKATKSDVDPLH--SFLAGSLAGAAEACITYPFEFAKTRLQLIDKAS-KASRNPLVLIYKTAKTQGIGSIYVGCPAFIIGNTAKAGIRFLGFDTIKDMLRDSE-----TGELSGTRGVIAGLGAGLLESVAAVTPFEAIKTALIDDKQSATPKYHNNG----------------------RGVVRNYSSLVRDKGFSGLYRGVLPVSMRQAANQAVRLGCYNKIKTLIQDYTDSPKDKPLSSGLTFLVGAFSGIVTVYSTMPLDTVKTRMQSLDST-KYSSTMNCFATIFKEEGLKTFWKGATPRLGRLVLSGGIVFTIYEKVLVMLA------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P43617-1", "uniprot_id": "YFL5_YEAST", "id": "P43617-1", "name": "Uncharacterized mitochondrial carrier YFR045W", "aln": "-------------------------MANQNSDLYKQITAGSVAAVFQTTMTYPFEYLKTGLQLQPKGT------AFEIILPQIKS-----YFVGCSALNVAAFGKTILRFVTFDKLCHSLNNNIDNNDNFQRLTGYNLLIAGTLTGIVESLFIIP-FENIKTTLIQSAMIDHKKLEKNQPVVNAKATFHKVATKSTPVARIEKLLPAVKHMYQTRGPAAFVQGTTATIFRQIANTSIQ---FTAYTAFKRLLQARN-----DKASSVITGLATSFTLVAMTQPIDVVKTRMMSQNAKTEYKNTLNCMYRIFVQEGMATFWKGSIFRFMKVGISGGLTFTVYEQVSLLLGFSSRS-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : **.::. : :*:* *: ** *** :. : : * . : . *: ** *: : : .* . ::.* :*: *:: : :* :*. :*.. * . . : : .* . :* .. ::* :* ::: : :: : * :. . * . *:*.:**** . :: :* .* .* *: ** :*:**: *: :: :. .:.* :*:.. :: ", "identical_positions": 47, "similar_positions": 88, "identity": "13.24%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130116-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O94910-1", "uniprot_id": "AGRL1_HUMAN", "id": "O94910-1", "name": "Adhesion G protein-coupled receptor L1", "aln": "MARLAAVLWNLCVTAVLVTSATQGLSRAGLPFGLMRRELACEGYPIELRCPGSDVIMVENANYGRTDDKICDADPFQMENVQCYLPDAFKIMSQRCNNRTQCVVVAGSDAFPDPCPGTYKYLEVQYDCVPYKVEQKVFVCPGTLQKVLEPTSTHESEHQSGAWCKDPLQAGDRIYVMPWIPYRTDTLTEYASWEDYVAARHTTTYRLPNRVDGTGFVVYDGAVFYNKERTRNIVKYDLRTRIKSGETVINTANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEGNNGRLVVSQLNPYTLRFEGTWETGYDKRSASNAFMVCGVLYVLRSVYVDDDSEAAGNRVDYAFNTNANREEPVSLTFPNPYQFISSVDYNPRDNQLYVWNNYFVVRYSLEFGPPDPSAGPATSPPLSTTTTARPTPLTSTASPAATTPLRRAPLTTHPVGAINQLGPDLPPATAPVPSTRRPPAPNLHVSPELFCEPREVRRVQWPATQQGMLVERPCPKGTRGIASFQCLPALGLWNPRGPDLSNCTSPWVNQVAQKIKSGENAANIASELARHTRGSIYAGDVSSSVKLMEQLLDILDAQLQALRPIERESAGKNYNKMHKRERTCKDYIKAVVETVDNLLRPEALESWKDMNATEQVHTATMLLDVLEEGAFLLADNVREPARFLAAKENVVLEVTVLNTEGQVQELVFPQEEYPRKNSIQLSAKTIKQNSRNGVVKVVFILYNNLGLFLSTENATVKLAGEAGPGGPGGASLVVNSQVIAASINKESSRVFLMDPVIFTVAHLEDKNHFNANCSFWNYSERSMLGYWSTQGCRLVESNKTHTTCACSHLTNFAVLMAHREIYQGRINELLLSVITWVGIVISLVCLAICISTFCFLRGLQTDRNTIHKNLCINLFLAELLFLVGIDKTQYEIACPIFAGLLHYFFLAAFSWLCLEGVHLYLLLVEVFESEYSRTKYYYLGGYCFPALVVGIAAAIDYRSYGTEKACWLRVDNYFIWSFIGPVSFVIVVNLVFLMVTLHKMIRSSSVLKPDSSRLDNIKSWALGAIALLFLLGLTWAFGLLFINKESVVMAYLFTTFNAFQGVFIFVFHCALQKKVHKEYSKCLRHSYCCIRSPPGGTHGSLKTSAMRSNTRYYTGTQSRIRRMWNDTVRKQTESSFMAGDINSTPTLNRGTMGNHLLTNPVLQPRGGTSPYNTLIAESVGFNPSSPPVFNSPGSYREPKHPLGGREACGMDTLPLNGNFNNSYSLRSGDFPPGDGGPEPPRGRNLADAAAFEKMIISELVHNNLRGSSSAAKGPPPPEPPVPPVPGGGGEEEAGGPGGADRAEIELLYKALEEPLLLPRAQSVLYQSDLDESESCTAEDGATSRPLSSPPGRDSLYASGANLRDSPSYPDSSPEGPSEALPPPPPAPPGPPEIYYTSRPPALVARNPLQGYYQVRRPSHEGYLAAPGLEGPGPDGDGQMQLVTSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RJW9-1", "uniprot_id": "A0A8M1RJW9_DANRE", "id": "A0A8M1RJW9-1", "name": "", "aln": "---------------------MMKLQTAALTFSALLCAVCAQGPGVSVRPRTAAVRLGETVSFQHR--VTSRAQPGMLE-------------SGKMNNQTLG----------------------------------VFVCPGTLVRVLEPSSVREAEDHSGAWCKDPLQAGDRLYVMPWTPYRTDMLYEYASWDDYIQNRVTTTYKLPSRVDGTGFVVYDGAVFYNKERTRNIVKYDLRTRIKSGEAVIVNANYHDASPYHRGGKSDIDLAVDEHGLWVIYTTEANNGRLVVSQVNPYTLRFEGTWQTSFEKRMASDAFVACGILYAVRSVYQDDDSEAGGDLILYAYDTRRNREEPVRIPFPNPYQHISSISYNPRDNQLYVWNNYIVLRYPLEFSPPQPTTDPLSTPLLSTTP---PSSLSSTVS-MGFSPTSVPSVTFHPVGAKNRA-----PAGRPTPG-----APDTDV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. *.*.*. : :..:* :.:* : * : *...: : . *:* :* * : **:* ******** :****:*.:*:*.:**************:***** ***** * *****:**: * ****:**.*************************************:** .*****:***: ***:********:******:**.*********:***********:*.::** **:**:.**:**.:**** ******.*: : **::*. ****** :.******.***:.**************:*:**.***.**:*::.* ::* ****. *:.*:**.* . :* ..:* ***** *: ** *.*. **: .* ", "identical_positions": 244, "similar_positions": 91, "identity": "16.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130116-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88923-7", "uniprot_id": "AGRL2_RAT", "id": "O88923-7", "name": "Adhesion G protein-coupled receptor L2", "aln": "MVSSGCR-MRSLWFIMIISFSPNTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTDCYLPDAFKIMTQRCNNRTQCVVVTGSDVFPDPCPGTYKYLEVQYECVPYMEQKVFVCPGTLKAIVDSPSIYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNSRQTTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETTYDKRAASNAFMICGVLYVVRSVYQDNESEAGKNVIDYIYNTRLSRGEHVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELFKTT---VSTTSSTSQRGPVSSTVAGPQEGSRGTKPPPAVS---TTKIPPVTNIFPLPERFCEALEMKGIKWPQTQRGMMVERPCPKGTRGTASYLCMASTGTWNPKGPDLSNCTSHWVNQLAQKIRSGEN-AASLANELAKHTKG-TVFAGDVSSSVRLMEQLVDILDAQLQELKPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRAETLDCWKHMNSSEQAHTATMLLDTLEEGAFVLADNLLEPTRVSMPTDNIVLEVAVLSTEGQVQDFTFHLGFKG--AFSSIQLSANTVKQNSRNGLAKVVFIIYRSLGPFLSTENATVKLGAD-LLGRNSTIAVN-----------------SHVLSVSINKESSRVYLTDPVLFSMPHIDSDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIVYKDG--VHKLLLTVITWVGIVVSLVCLAICIFTFCFFRG--LQSDRNTIHKNLCINLFIAEFIFLIGIDKTQYTIACPVFAGLLHFFFLAAFSWMCLEGVQLYLMLV----EVFESEYSRKKYYYVAGYLFPATVVGVSAAIDSKSYGTLEACWLHVDNYFIWS-FIGPVTFIILLNIIFLVITLCKMVKHSNT--LKPDSSRLENINNYRVCDGYYNTDLPGYEDNKPFIKSWVLGAFALLCLLGLTWSFGLLFVN------EETVVMAYLFTAFNAFQGLFIFIFHCALQKKVRKEYAKCFRH------WYCCGGLPTESPHSSVKASTSRTSARYSSGTQSRIRR-----MWNDTVRKQSESSFISGDINSTSTLNQGMTGN--------YLLTNPLLRPHGTNNPYNTLLAETVVCNAPSAPVFNSPG---HSLNNTRDTSAMDTLPLNGNFNNS---YSLRKADYHDGVQVVD--CGLSLNDTAFEKMIISELVHNNLR-----GSNKTHN------LELKLPVKPVIGGSSSEDDAIVADASSLMHGDNPGLEF------RHKELEAPLIPQRTHSLLYQPQKKVKPE--ATDSYVSQLTAEADEHLQSPNRDSLYTSMPNLRDSPYPESSPDMAEDLSPSRRSENEDIYYKSMPNLGAGRQLQMCYQISRGNSDGYIIPINKEGCIPEGDVREGQMQLVTSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JZZ7-1", "uniprot_id": "AGRL2_MOUSE", "id": "Q8JZZ7-1", "name": "Adhesion G protein-coupled receptor L2", "aln": "MVSSGCR-MRSLWFIIIISFSPSTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTDCYLPDAFKIMTQRCNNRTQCIVVTGSDVFPDPCPGTYKYLEVQYECVPYSKMLVFVCPGTLKAIVDSPCIYEAEQKSGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNSRQTTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETAYDKRAASNAFMICGVLYVVRSVYQDNESEAGKNTIDYIYNTRLSRGEYVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELFKTT---ISTTSSASQRGPVSSTAAGPQDGSRGTKPPPAVS---TTKIPPVTNIFPLPERFCEALDWKGIKWPQTQRGMMVERPCPKGTRGTASYLCMASTGTWNPKGPDLSNCTSHWVNQLAQKIRSGEN-AASLANELAKHTKG-HVFAGDVSSSVRLMEQLVDILDAQLQELKPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRAEALESWKHMNSSEQAHTATMLLDTLEEGAFVLADNLLEPTRVSMPTENIVLEVAVLSTEGQVQDFKFPLGLKG--LGSSIQLSANTVKQNSRNGLAKLVFIIYRSLGQFLSTENATIKLGAD-LMGRNSTIAVN-----------------SPVISVSINKESSRVYLTDPVLFTLPHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDG--VHHLLLTVITWVGIVVSLVCLAICIFTFCFFRG--LQSDRNTIHKNLCINLFIAEFIFLIGIDKTKYTIACPVFAGLLHFFFLAAFSWMCLEGVQLYLMLV----EVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTVQACWLHVDNYFIWS-FIGPVTFIILLNIIFLVITLCKMVKHSNT--LKPDSSRLENINNYRVCDGYYNTDLPGYEDNKPFIKSWVLGAFALLCLLGLTWSFGLLFVN------EETVVMAYLFTAFNAFQGLFIFIFHCALQKKVRKEYGKCFRH------WYCCGGLPTESPHSSVKASTTRTSARYSSGTQSRIRR-----MWNDTVRKQSESSFISGDINSTSTLNQGMTGN--------YLLTNPLLRPHGTNNPYNTLLAETVVCNAPSAPAFNSPG---HSLNNARDTSAMDTLPLNGNFNNS---YSLRKADYHDGVQVVD--CGLSLNDTAFEKMIISELVHNNLR-----GGNKTHN------LELKLPVKPVIGGSSSEDDAIVADASSLMHGDNPGLEF------RHKELEAPLIPQRTHSLLYQPQKKVKPE--ATDSYVSQLTAEADDHLQSPNRDSLYTSMPNLRDSPYPESSPDMAEDLSPSRRSENEDIYYKSMPNLGAGRHLHMCYQISRGNSDGYIIPINKEGCIPEGDVREGQMQLVTSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95490-1", "uniprot_id": "AGRL2_HUMAN", "id": "O95490-1", "name": "Adhesion G protein-coupled receptor L2", "aln": "MVSSGCR-MRSLWFIIVISFLPNTEGFSRAALPFGLVRRELSCEGYSIDLRCPGSDVIMIESANYGRTDDKICDADPFQMENTDCYLPDAFKIMTQRCNNRTQCIVVTGSDVFPDPCPGTYKYLEVQYECVPY----IFVCPGTLKAIVDSPCIYEAEQKAGAWCKDPLQAADKIYFMPWTPYRTDTLIEYASLEDFQNSRQTTTYKLPNRVDGTGFVVYDGAVFFNKERTRNIVKFDLRTRIKSGEAIINYANYHDTSPYRWGGKTDIDLAVDENGLWVIYATEQNNGMIVISQLNPYTLRFEATWETVYDKRAASNAFMICGVLYVVRSVYQDNESETGKNSIDYIYNTRLNRGEYVDVPFPNQYQYIAAVDYNPRDNQLYVWNNNFILRYSLEFGPPDPAQVPTTAVTITSSAELFKTI---ISTTSTTSQKGPMSTTVAGSQEGSKGTKPPPAVS---TTKIPPITNIFPLPERFCEALDSKGIKWPQTQRGMMVERPCPKGTRGTASYLCMISTGTWNPKGPDLSNCTSHWVNQLAQKIRSGEN-AASLANELAKHTKG-PVFAGDVSSSVRLMEQLVDILDAQLQELKPSEKDSAGRSYNKLQKREKTCRAYLKAIVDTVDNLLRPEALESWKHMNSSEQAHTATMLLDTLEEGAFVLADNLLEPTRVSMPTENIVLEVAVLSTEGQIQDFKFPLGIKG--AGSSIQLSANTVKQNSRNGLAKLVFIIYRSLGQFLSTENATIKLGAD-FIGRNSTIAVN-----------------SHVISVSINKESSRVYLTDPVLFTLPHIDPDNYFNANCSFWNYSERTMMGYWSTQGCKLVDTNKTRTTCACSHLTNFAILMAHREIAYKDG--VHELLLTVITWVGIVISLVCLAICIFTFCFFRG--LQSDRNTIHKNLCINLFIAEFIFLIGIDKTKYAIACPIFAGLLHFFFLAAFAWMCLEGVQLYLMLV----EVFESEYSRKKYYYVAGYLFPATVVGVSAAIDYKSYGTEKACWLHVDNYFIWS-FIGPVTFIILLNIIFLVITLCKMVKHSNT--LKPDSSRLENI------------------------KSWVLGAFALLCLLGLTWSFGLLFIN------EETIVMAYLFTIFNAFQGVFIFIFHCALQKKVRKEYGKCFRH------SYCCGGLPTESPHSSVKASTTRTSARYSSGTQSRIRR-----MWNDTVRKQSESSFISGDINSTSTLNQGMTGN--------YLLTNPLLRPHGTNNPYNTLLAETVVCNAPSAPVFNSPG---HSLNNARDTSAMDTLPLNGNFNNS---YSLHKGDYNDSVQVVD--CGLSLNDTAFEKMIISELVHNNLR-----GSSKTHN------LELTLPVKPVIGGSSSEDDAIVADASSLMHSDNPGLEL------HHKELEAPLIPQRTHSLLYQPQKKVKSE--GTDSYVSQLTAEAEDHLQSPNRDSLYTSMPNLRDSPYPESSPDMEEDLSPSRRSENEDIYYKSMPNLGAGHQLQMCYQISRGNSDGYIIPINKEGCIPEGDVREGQMQLVTSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GDD5-1", "uniprot_id": "A0AC58GDD5_DANRE", "id": "A0AC58GDD5-1", "name": "", "aln": "MASSLWKRSLVLALLLTVIFLQPSEGFSRAALPFGLVRRELSCEGYPIDLRCPGSDVIMIETANYGRTDNKICDADPFQMDNINCYLPDAYKIVSQRCNNRTQCVVNTGSDVFPDPCPGTYKYLEVQYECVPY----IFICPGTLKAVGDPTLEFEAEQQSGAWCKDPLQAGDKIYFMPWTPYRTDTLIEYASLDDLRSGRQTTTYKLPHRVDGTGFVAYDGAIFFNKERTRNIVKFDLRTRIKSGEAIVASANYHDTSPYRWGGKTDIDLAVDERGLWVIYATEQNNGRIVLSQLNPYTLRFEATWETVYDKRSASNAFMVCGVLHVVRSTYEENESEASKSQIDYVYNTKLGQGEYVNILFPNKYQYIAAVDYNPRDNQLYVWNNFYILRYNLEFGPPDPDEEPTVSDDATSTLPPRRSTPAVLKTTLSLSFTQRPSLNSSISTDPLTEEHPEPPAD---PTAAASVP---PASRRFCEPTEKRGISWPKTHRGLTVERPCPRGTRGIALFLCLTG-GVWNPKGPDLSNCTSHWVAQVAQKIRSGEN-AASLANELAHHTQG-SVFAGDVSSSVRLMEQLVDILDAQLQELKPDQKDSPGRSFNKRQKRERTCRAYMKAIVDTVDNLLRPEALKSWEDMNSTEQTHAATMLLDTLEEGAFVLADNLIEPAVVRMPAENIMLDVYVLSTDGQIQDFRFPQTSK---RGATIQLSANMVKLNSKNGVAKLVFVLYKHLGHFLSTENATVRLMGD-GGLRNHTLTVN-----------------SHILSASINKESSRVFVSEPVIFTLEHLDTENYFNPNCSFWNYSERSMSGYWSTQGCKLLSTNKTHTTCSCSHLTNFAILMVHRDSHAGEGS-VHELLLTVITRLGIAVSLVCLAISIFTFCFFRG--LQSDRNTIHKNLCINLFIAELLFLVGINMTEPPIVCSVIAGVLHFFFLAAFSWMCLEGVQLFLMLV----EVFESEFSRRKYYYASGYLFPCVVVGISAAIDYKSYGTKKACWLRVDNHFIWS-FIGPVTFIILLNLIFLVVTMYKMVKHSMS--MKPDSSRLESIR------------------------SWVFGAFALLCLLCLTWSFGLLFLN------DSSVIMAYLFSIFNTLQGMFIFVFHCLLQKKVRKEYSKCFRQ------SQCCRTHPSEGPHSVNKSSASRSTARYSSATQSRIRR-----MWNDTVRKQSESSFISGDINSTSTLNQGMTGN--------YLLTNPLLRPHDTNNRYNNLLAETIVCSTPSPPAFHSPGQ--RSLSNSRDVSTMDTLPLNDNFNNS---YSLREDDYEDPAITCPTGCEIRLDDAAFEKMIISELVHNNLRPRRNQSSSKCQADRNSSPQENCADIDEGVGDRNECENAETDTSAMPLSSCHPAMELLLLNPNHREALEVPLLPQRTHSLIYASQKVIRPHKISRDTQQDEGEVKKEDDSSPNNRDSLYTSMPNLKDSDLVIG--EEENSPCSSAQSETQEQCCKSLPDLGDGTPAMSYYQISASLS------------LEAESANDGQMQLITSL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z7G7-4", "uniprot_id": "LPHN_DROME", "id": "A1Z7G7-4", "name": "Latrophilin Cirl", "aln": "----------MLPTILSISYEHISLDLSKYQTAY-------ACEGKKLTIECDPGDVINLIRANYGRFSITICNDHGNVEWSVNCMFPKSLSVLNSRCAHKQSCGVLAATSMFGDPCPGTHKYLEAHYQCISA-------------------------AQTSTTTNRPSPPPWVLSNGPPIFGNGSGLIHPPGVG----AGAPPPPRLPTLPGVVGISGNPGLFNVPPQHTAVTHSTPSSSTTAVGGGRLKGGATSTTTTKHPAGRHDGLPPPPQ-----LHHHHNHHGEDTASPTKPSSKLPAGGNATSP---SNTRILTGVGGSGTDDGTLLTTKSSPNRPPGTAASGSVVPGNGSVVRTINNINLNAAGMSGGDDESKLFCGPTHARNLYWNMTRVGDVNVQPCPGGAAG------------IAKWRCVLMKRIPDSGYDEYDDDISSTTPAPSGGDCLHNSSS------------CEPPVSMAHKVNQRLRNFEPT---------------------WHPATPDLTQCRSLWLNNLEMRVNQRDSSLISIANDMSEVTSSKTLYGGDMLVTTKIIQTVSEKMMHDKETFP------------DQRQREAMIMELLHCVVKTGSNLLDESQLSSWLDLNPEDQMRVATSLLTGLEYNAFLLADTIIRERSVVQKVKNILLSVRVLETKTIQSSVVFPDSDQWPLSSDRIELPRAALIDNSEGGLVRIVFAAFDRLESILKPSYDHFDLKSSRSYVRNTAILSNDSDVNAGEIQQRLRILNSKVISASLGK-GRHIQLSQPITLTLKHLKTENVTNPTCVFWNYIDH----AWSANGCSLESTNRTHSVCSCNHLTNFAILMDVVDEHQHSLFTMFDGNMRIFIYISIGICVVFIVIALLTLKLFNGVFVKSARTSIYTSIYLCLLAIELLFLLGIEQTETSIFCGFITIFLHCAILSGTAWFCYEAFHSYSTLTSDELLLEVDQTPKVNCYYLLSYGLSLSVVAISLVIDPSTYTQNDYCVLMEANALFYATFVIPVLVFFVAAIGYTFLSWIIMCRKSRTGLKTKEHTRLASVR------------------------FDIRCSFVFLLLLSAVWCSAYFYLRGAKMDDDTADVYGYCFICFNTLLGLYIFVFHCIQNEKIRREYRKYVRQHAWLPKCLRCSKTSISSGIVTGNGPTAGTLCSVSTSKKPKLPLGVSEEAHDDPQQQQQTPVPITEDAIMGATSDCELNEAQQRRTLKSGLMTGTLQAPPQTLGGHVVLERGSTLRSTGHASPTSSAGSTHLIFAHKQQQQQQQQGPLGESYYHQPDYYSWKQPSTGTGGLKTPREYYNNAGAAASSPQQAHEVFYWTQKPNSGHNGKKKRG-------AGGVPASPSGSLHSRTAAASQVLFYPSYKKTKPGQPTG--YPQYAEALDPPLATGNAAAYYQQQQQLRRQQLHQQQQQQQQQQLSSDEEQAEQHAHLLHLQRRAGSQQQLPAPPPHMAQYQQEFMQRQYRNKHSNCDLGMGDAYYNQGSVGGADGGPVYEEILSNRNSDVQHYEVGDFDVDEVYNNSVGTGVFNNMRAAVAAGGSRYGGGSLSGGSVSSRSQQQQLKKQQQQQSLAQQRSARRCTADDDDDEDEEEDEEATAAEQLHDSVCDEDEEEDESDLEDDAHGLPPQSDERMRRLMAMQDEDFKRRFQRQLRKHGAPLDYGALPPGAGPQPEHNGAVFGVSGGVGEGSLRGAFRQQQQQALNAKSPGGRLAVNELFGHGNSGPPLPPANQTPAQKRQQLQKLSPQSTTSSSSHTSHSNPNPHPHQLTHPHPHQHPPHHQQRHLSAMLDENNTVRCYLEPLAK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: : : : .:*: .: :*** : :.* .*** : ***** . .**: . . :* :*.: .::..** :: .* * :.:.:* ******:****.:*:*:. ::.: : * . : * . . **. ..: . ... :** . .*: * . . ::* . : * . : . *:. : .*: * . : :: .:::* . * :* : . * : :. : * . .. .:*...: .: : . * : * *.:. . :.:*: . * * * . : . . : * *. . . . **. . . : *.: *:* ***::* * *: :: ::.. :. *:**:::. *.. ::.**: :.:::: : : : : : : . ::** ::.:*.* .*** . *..* .:*. :* :.** ** ** .**:***.::. * ..**:*.* **.*. ... * : *:*. : **..*:.::** : * :*... . * .. ** :: * * ::*.*:.* . :: :::*: ::: *:..:* *..* **** :: **::**.* .**:*::.*:*.********* : . :.. : :: :.* :.:* :.*.::*: :*.* ::* *.:*:..: : *: *::**:**: *: .* * .:: .** :*:. :*:* *..: : *. : .: .: : ** .* :. **.:* .** .:* . * * * :::: *: ** .::: : : .:: * ::* : . : :** .: : :*.:* ** .*. . :::. : : : .* * **:: *::**:*** ::*:*:** * .*: * . .. :..:: : . *:..:.:: :*. ::*. . *: * :* : :. *:*..* * * . : * : : .: .. *.* : : :: . : **. .: :. ** :: . . :* . *:.: . : ...* : . . . * :*. : *: ** . .: : *: : . : .: . ::. : . *: . :. . : : : .: :. .:* . : . . : .. : ::: : . ", "identical_positions": 251, "similar_positions": 484, "identity": "13.49%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130117-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E5FYH1-1", "uniprot_id": "TOPZ1_MOUSE", "id": "E5FYH1-1", "name": "Protein TOPAZ1", "aln": "MRPPATPPDPTKEPGCKGTTRGLRKRGLPLTPEPGEGGGCSLEARGCEEESRQKQRMVTQAS-GREETEGDK-----------------------------------------------LAKENGKITEAPSDDPQPGTDLVRKTSITSSESLQTVECSEFQNMAFLQSLDKEELGEGIKRRMRIKKCKSLENPPLEITKNEATQNIKVEFQDELFKNTPKHSCNSLSPGVEKNCSFELHDY-SFLHSEGCNNENNFEDKPHDVCLHTEENSLKLKKENLRNLAEKDDTRTTTKLLKTEKSVIAS-KLLLEESHLYQNKNNGLTSCLQSEKNKYSVEENNTGRKHRKKMKSGK--EEKNINLTLSNVCNNSVLVLQENQMGMEGKEAETLEPKKSFLKALRKINHNTLPPVDHLC-LPKTVG-KTSSRHHINAMLQKTLESSLKEDIKNTSESLGCKRIEPEKYNKSMISSTVKSPSDGHHMEKRSPRGDLRSETEESKVSCCRTIPMTGKRVWPFYSCARISAQCWKKTSLSDLNYSLLGPLENVRQHDSIIHQMNQTHLPDSK-LLQPSLTERTTESSRKEMYDSDLSCLSSVSSVESTVMDIKEAMS-HDKKTKLEEPSRNGA--EVVSNATEDTQLSNITQSLTGNKKRK-GNLSKLNLTVASQESQETNNCANKTVHRKVCITKQTLVAPDLVKILNTGRLTNFKIPLLKNKTGKRGAVSARSSEREAYSPLELLDSLSGVEAKQNRNKENICTTS-GPQSLNLHSCIAPGQASSHSFYNKNSCTSS-SFTKKGYDNKACNHISEPGNIISNKESISMKIENNTFSCDLGYIDQS-SFCSKKQEAFVPISSEISGRKMTKSISELKLGFPDILKAYEDDVLLIDVIQDDPELFGISSEGDLSFASEVSKISQEPRVSEDQPTADFKHMHLPGKKEPGDLSKEVALLDPGLLKLESCPSLSAAKEPQHDPEGAAISL-EATEETVVSGSLEGLSEQARASDSDAKCISSDKATVMEEQESTHEIFKSKDSRNVESAT-ECQLATLGPNPLCSSALPVNLSS-HQDVVSTPWINDVRFPGRHSVLQLQNPETCEIFKREKNMGVFQKPLGLLIPHRYCKLHFNTLRGCERA-QCKFVHVPEQGDEKICMDVFRKYISVNEQRLLHRAAYIFLEYYRKFPPGIHFSLQVLNDLLISLLKHCLLKEVFQVVQLSIMAKMLPALKILLKIFEYVAAMKLRNAVPALIEIFCKFIEAGMVPDPEHLNYIVKLLHQAQASQQEISAVLQAKSRLRVRQLKKNWKCDLDSALSEVETCKEKSDWTKLGNLYISIKMSCEEFADLQRFCACVAETLTEDYKEERPGVPFCEFAETVSKDPQYSEVDKTLLGRIGISAVYFYHRLLLWAKGRKVLDILYELKIHFTSLKGLTGPEKEAPRCQIVNVAAEIFIKSGSLDGAIWVLRESEWIINTPLWPCDRMDVLNRHNLLCTIAHEILGKNLYKQTFEVLRNLPSFQNSQEMMGVSQSSLLFNELLDACIESNSLGISSSVAEFMVAKSIPIDFSFLRRLITSLGRSCLWLKARAHYKSALSLGCYPPLEGNLHRKLLLVPSYLSEIEMLLAMEIFLVSNASGIQSAGMGAPTQVLQIVLKRCEESKSRSKDEYQAAVERLVMAARISDPKLFIKHMTVNINKEQVYSLEHCSALKWLKENMKWAGKVWLFTNH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N9V7-1", "uniprot_id": "TOPZ1_HUMAN", "id": "Q8N9V7-1", "name": "Protein TOPAZ1", "aln": "MRRPP-PLGPTTASGPEGNVRNLQKR---QAPGPGAAGGCGPEAGGCRE-NKQKRRMVARATPGRGEVESDKSVAASGAGKAARRQVEGRRGPVSPSDSSDPRGLEAAKEAELPLQTERHTKEKRKVTEASSDDPQPGLDLVRKESLTSSESFQTVEC--------LQSLGKESIIEGIKRRIRNKKLKSLENPPLKITENEATQNIKVEFQDELYKNTPKYSCNILSPEVENNSVLKLRDCNCFPHSKGCNDENNLPYKPDGGCMHVAEN--FSKKENLRSLAEKSDTNSIPQLLQTEENVMGVNKLLPEESDLYQSKTNGLLSCLQHEKNKYSIEESSVGRKPRKRMKLSEKADETVTEMNFSNEYNKSELMLQENQMIADGKEAETKSP----LNVLRKVSHNTVSLMDHLLSVPETVEKETSSEHHVNAVFQKTIEPLLKEETENASEPLGYESMASKEDFKSMKSFIGKSPNE-YHIERRSSREDLRSASEELKLSCQRTIPMTGKRTWPYYSCARISAWCWKKASLPESSYFLRGSQESCRQVDVPKHQTNQTHLTDSKLLLQSSLTETNTESSSKEKLDSNSNCLSSVSAVEPTLMVIKEPIIKDDKKIKSEELSRRGS--EVISNTTEDTQLTSETQSLTGNKKKARGNLTKLNLTATSKDGQEANNSAGKTIHRKACIAQQTFIVPDLVKILNTGRLTNFKIPLLKNKSEKRKEVNAKSSEREAYSPLELLDNLSGADVRQNRSKENVSMMMLGPQTLSIRNSVTPVQASSDSFYNKKSYSISPSFTKQGNNSKPSNHVSEPGNIVSNKEVASLTVENNAFSCDPGYVEKSPSFCCNEQETFRPVSSEVRGRKITKNFSEV--GFPDILKAYEDDVLLIDVIQDDPDLFGVSNEGELSFTSEVPKISQEPNVAGEHQSTDSKYMETPVKKEPSDDLRELPVLDCGWIKPDICASNSAESEIKRDPKDVNTSLGEVANETSENETLGDFSEQIKGSDLDEKHRFTDKVITKEEKENIYEVCKSKDSRNADFMVGECQFAVPVPKPLCLLVPPLNLSGRQEDTILNTWMNDFRFLGKHSVLKLQNPETCEIFKREKNVGVFQKSLGLMIPYKYCKFHFNTLRGCERP-LCKFAHVPEQGDEKVCMDVFKKYININELCLLQRAVNIFMEYYRKFPPGVYFDLQVLNDLLNSLLKHCLLKEVFQIVNLSIMVKMLPSLKILLNIFEYVATMKLRNAVPALIDIFCKLVEAGMVLDPEHFNYIVKLLYQVQASKQEITAVLEMKSRLQMRRFKKNWKCDLDSALNKLEHCKEKGDWTKLGKLYINVKMGCEKFADFQTFCACIAETLTKNYEDERPDIPFCEFAETVSKDPQNSKVDKGVLGRIGISAMYFYHKLLQWSKGRKVLEKLYELKIHFTSLKGLIGPEKLASRCQIVNVAAEIFLKSGSLDGAIWVMRESEWIINTPLWPCDRLDVLNRHNLLCTIAHEILAKSLYRQTFEVLQNLPGFQNSQETVEVSQYSLLFNKLLGSCIESSSLGMSSSVAEFMISKSIPIDFSFLRRLITSLGRSRLWLKARAHYKSALSLGCYPPLEGNLYRKLLLIPSYLSEIEMLLAIEIFMVSNASSIQSP--GTSTQILQIVLKRCEDNQSRSNDDYQAAVERLIMAARISDPKLFVKHMTVNVNKEQVYSLEHCSALKWLKENMKWAGKVWLFSNH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0N4SUA6-1", "uniprot_id": "A0A0N4SUA6_DANRE", "id": "A0A0N4SUA6-1", "name": "Protein TOPAZ1", "aln": "-------------MFPCGTRIKLKRD------------SFKPENKPEPNKRRWTGSNVKPVCAVNPPVDGGS-------------------------------------------------------PKPATADPGTVSSKVSVITGADPEAMPASKN------------RLSEHKREIFCRLRLALCFARNKP-----RNGGKRVIVGPTDAHALSVINSVESGNVNVSVEPPELIPPARQSVKHGAQNTLSRPTVPRREKGTQRRLFAG---EAKTAIRTEARRSRASLTGRTSANFSSKVELRRLRSEERSRKRSVKN--ACCALCGDVKYNPPPPPSSKNLVRLLNPRP-------------RAGRPSLSAEKQRTPSASRHASALEKNP--TVKLCDVGRVFRIASRDFSCVLPAVLKQTASRRAQQQCLQTEFGVLTHPHPHSIRKRRRSRKLSTATKHSCASLSSGDAPCGGAHISEGS-----LEESDACLVEDPETMRLSESPDTVAPACANNCPEKQKHCPVNHISGNTSSPERRVPPLVLRRVSVNGFGFRSED----DDRESGPDEDGRNQDSDAESANAPESFSCQRTQAYIFIPKSSCARTCKPWPFPRTGPPEELRSPRNGARWIITATFTNTAQDDEEKNERSEAAEEVYSRKSHADTPCRLISGDIPDVLNQQSSVLCENTSTCVLKRTSGFSVTAISEHAELN-QSQEHSTEQVNSCKLDGCGFEASLEANGLLRHHSLLDHEDHPDAPGVWEPADHLVGDSK--CAKFSILPISQFEDQSRKADEGAVYNPALLSQMCIKVGVLKAQDSSSVDQTEGESAAHSHSSNPEGEVKPASDGQTHTDMSS----------------EEENQDAGGVSAPSSSSSDDDDDDDGVCSMNTNNNNNTQACSQSHRVEESFLDVSRAYEEDVLVLDVIQDDPELFGTVVSEAKTQQDAPTKNQDTLTKMEDQHCEVIWEQHTEG---TSKVAEDVQTDHLSDSGSKVNEMQVCRSQPVQSLNTVKSENAGIDCNNNQPSRDSSNLNSISVISSR------APRPVTDSCFSGREVTAKEPPALRTPHIS-------------------YCRFYFSDHSTCLRSGVCRFLHVPRDGDETFCMEMVKKFCHAGKVVLILRAVEVFMGYYSRCPPSGSFSQETVNSLLSILLNMGLLREFLAVLNLLLTHKKLPPPELVLAVFKFASDRRLINFVPELILLTSKIVESGCVFTVDQCEVMQSHLHLMQVPRQQMDIFMAVKCRALATNPHTSELSHLTQAVVRVEMLKQQEDWSGLALVFYSVCSGSHSNNELLRFCCCVTMALLKEPKD-KHTVPYELFADAVCQR-EPSDEVKSILGRIGVSLIFRYHRTREWSKGVKLVNVMLRLQIEFIMQKGLMGNEHRVSRCQLVSMAAELFLHSGSIEGALKLLRADGWFVSSSVWPCEAADVEIRKRVLTLLA----GKTSHRDAFEILTNLPGLRQPINGVQISDYTDMFNAHLRVCLLKQTLPVAADILEFMLTRSLVPETQQLQNLIHRLGKQNMWSRARALFRRARSAGFYSSVVCEAD--ALFLPCGLSEIEMTLAFEMFITFINSSLSAH-----THPLLITLRRQAGVENVTESVYLAAGCRLLSAALIPNPKLSIRYTAVNQQQEQLFTLDRASAHKWILQNSCWALEVWAS---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. *:: . * : : . * . . .:... .:..: ** . . * : :..*:: : : .. . * *:* : ::* .* ..: * : . . . ... :. ** : ::. .. .. : .. : . * :*. *.:. : : . .. : :* ** :. .* .* . **. .:: : :: ... * :::: .:.*.: . * .:.: .: : :* :*:*.: : :*. : : . .. : . : . .. .:* *:.. * . :: :. .*: :: . :**. .. *: .: . . .. . . * : ... . . *.. :: *:: .. : : * * . :. * .* *. *: * . : . * : *.:... .: :: . *:..: . . : . : :*: : : .. * :.*.:. :.::: . . :*:*: . *: . :. :.. :..: *:: .: . ..*. * * .* .:. . . . . : :. ::.: : . : *...: : . * *. .::. *:: . :. .. . ..:.: .. * .: .::.... : .: ..:. . * . :: * : . : : . :: . : : . : . ..* : . . . * : : :* :: : : :*: .. .: * :.* * *:. . : . :. **:::*. * *. *:* ***.:***..**::.:*: .: *: **. :*: ** : **. *. :.:*.** **: **:*.: :::* : * **. :::* :*::.: :* * ** ** : .*::*:* * :: : : . *: *..:*:: .: *.* . :.. ..* .*: .:* *:: **: *. :: .: .... :: **.*:: :* :: :: : :*: **::*.: : *. * :*****:* :: **: *:** *::: : .*:*.* *** * *: ..***:*.:***:*::***::**: ::* . *::.:.:***: ** *:.:* :* .*. ::::**:* ***.:::. : : :*: : :** * *: ..:* :::.: ***:::*: : . *:.** **:. :* :*** :: * * * *..: : *::*. ****** **:*:*:. *.:.: *: * *.*:* :. ::. * ** **: ** *.:*** ::: :** ::**:::*::.** **: :* ** :** ", "identical_positions": 266, "similar_positions": 571, "identity": "15.47%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130129-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N3J2-1", "uniprot_id": "METL4_HUMAN", "id": "Q8N3J2-1", "name": "N(6)-adenine-specific methyltransferase METTL4", "aln": "MSVVHQLSAGWLLDHLSFINKINYQLHQHHEPCCRKKEFTTSVHFESLQMDSVSSSGVCAAFIASDSSTKPENDDGGNYEMFTRKFVFRPELFDVTKPYITPAVHKECQQSNEKEDLMNGVKKEISISIIGKKRKRCVVFNQGELDAMEYHTKIRELILDGSLQLIQEGLKSG-FLYPLFEKQDKGSKPITLPLDACSLSELCEMAKHLPSLNEMEHQTLQLVEEDTSVTEQDLFLRVVENNSSFTKVITLMGQKYLLPPKSSFLLSDISCMQPLLNYRKTFDVIVIDPPWQNKSVKRSNRYSYLSPLQIQQIPIPKLAAPNCLLVTWVTNRQKHLRFIKEELYPSWSVEVVAEWHWVKITNSGEFVFPLDSPHKKPYEGLILGRVQEKTALPLRNADVNVLPIPDHKLIVSVPCTLHSHKPPLAEVLKDYIKPDGEYLELFARNLQPGWTSWGNEVLKFQHVDYFIAVESGS--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F6U3-1", "uniprot_id": "E7F6U3_DANRE", "id": "E7F6U3-1", "name": "", "aln": "MSVVCCNSWGWLLDSSSHID----------------KDFQRCVCYN-------------------EANGLEEN------THFT--CCFKRQYFNILMPHMQQSTAMSGFPLDSGK-HDSAEHEKIELQTRKKRKRKHHDLNTGEIEANIYHDKVRSVVLEGSRALLEAGRQCGYFTEALTESQTISTPSESTSAHECQLAAFCDLAKQLPLSEESPVHTLS---RDGQNPALDLFSSITENPFDCACEITFMRERYLLPPRCRFLLSDVTRMDPLVNSGDKFDLIVLDPPWENKSVKRSNRYSSLPSSQLKKLPVPALAAPGGLVVTWVTNRAKHRRFVREELYPHWAVEVLAEWLWVKVTRSGEFVFPLDSQHKKPYEVLVLGRCRSTSDHTDRCSAVNEL--PDQRLLVSVPSTLHSHKPSLAAVLKPYIRREPRCLELFARSLQSDWSCWGNEVLKFQHCSYFSRHTDQEPTSDTLQRTHSHLQSTGLLETPETAR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** * ***** *.*: *:* .* :: ::. ** ** *: : *:: *:: :. . :. : .. :::*.:. *:::: :* **::* ** *:*.::*:** *:: * :.* * .* *.* .: . : . . *.*: :*::**:** :* :**. .* . . *** :.** . : **:* ::*****:. *****:: *:**:* ..**:**:****:*********** *.. *::::*:* ****. *:******* ** **::***** *:***:*** ***:*.********** ****** *:*** :..: . * : ** * **::*:****.*******.** *** **: : . ******.**..*:.********** .** . . ", "identical_positions": 196, "similar_positions": 121, "identity": "39.28%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130131-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JUW3-1", "uniprot_id": "A0A0G2JUW3_RAT", "id": "A0A0G2JUW3-1", "name": "", "aln": "MGVIPGCCEVPEQSFMPLVIHLSNSLRHFQLKINLVFTEAQRLREERASLTRCQNLPVPSPTSGVPCPLSRGCRRGAMSCLLNNMVPVGLALL-VCGVQAFFLPNTMSLERLLSKYQHT-EPHS-------RVRRAIPMSDRQEILMLHNKLRGQVYPPASNMEYMTWDEELERSAAAWAQRCLWEHGPASLL--VSIGQNLAVHWGRYRSPG------FHVQSWYDEVKDYTYPYPHECNPWCPERCSGAMCTHYTQMVWATTNKIGCAVHTCRSMSVWGDIWENAVYLVCNYSPKGNWIGEAPYKHGRPCSECPSSYGGGCRNNLCYREEHYHQ-KPEVDEMNEVESPPAPEETHVWVQPRVVKPSK-------TKKTPVVNFMTQVVHCDTKMKDSCKGSTCNRYQCPAGCLNNKAKVFGSLFYESSSSICRAAIHYGVIDDRGGLVDVTRNGMVPFFVKSQKNGLESLSKYKPSSSFTVSKVKETAVDCHTTVAQLCPFEKPATHCPRVRCPSRCGEEPSYWAPVYGTNIYADTSSICKAAVHAGVIVDEVGGYADVMPVDKKKSYVGSLRNGVQSESPSTPQNGNAFRIFPVRQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZQ2-1", "uniprot_id": "CRLD2_MOUSE", "id": "Q8BZQ2-1", "name": "Cysteine-rich secretory protein LCCL domain-containing 2", "aln": "-----------------------------------------------------------------------------MSCLLNNMVLMGLALL-VCGVQAFFLPNTTSLEKLLSKYQHA-EPHS-------RVRRAIPMSDRQEILMLHNKLRGQVYPPASNMEHMTWDEELERSAAAWAHRCLWEHGPAGLL--RSIGQNLAVHWGRYRSPG------FHVQSWYDEVKDYTYPYPHECTPRCRERCSGPMCTHYTQMVWATTNKIGCAVHTCRNMNVWGDTWENAVYLVCNYSPKGNWIGEAPYKHGRPCSECPSSYGGGCLNNLCHRAEKPHKHKPEVDMMNEVESPPAPEETHVWVQPRVIK----------TKKTPVINFMTQVVHCDTKMKDSCKGSTCNRYQCPAGCLSNKAKVFGSLFYESSSSICRAAIHYGVIDDRGGLVDVTRNGMVPFFVKSQKNGMESLSKYKPSSSFTVSKVTETAVDCHATVAQLCPFEKPATHCPRIQCPARCGEEPSYWAPVYGTNIYADTSSICKAAVHAGVIVDEVGGYADVMPVDKKKSYVGSLRNGVQSESLNTPQNGNAFRIFAVRQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H0B8-1", "uniprot_id": "CRLD2_HUMAN", "id": "Q9H0B8-1", "name": "Cysteine-rich secretory protein LCCL domain-containing 2", "aln": "-----------------------------------------------------------------------------MSCVLGGVIPLGLLFL-VCGSQGYLLPNVTLLEELLSKYQHN-ESHS-------RVRRAIPREDKEEILMLHNKLRGQVQPQASNMEYMTWDDELEKSAAAWASQCIWEHGPTSLL--VSIGQNLGAHWGRYRSPG------FHVQSWYDEVKDYTYPYPSECNPWCPERCSGPMCTHYTQIVWATTNKIGCAVNTCRKMTVWGEVWENAVYFVCNYSPKGNWIGEAPYKNGRPCSECPPSYGGSCRNNLCYREETYTP-KPETDEMNEVETAPIPEENHVWLQPRVMRPTK-------PKKTSAVNYMTQVVRCDTKMKDRCKGSTCNRYQCPAGCLNHKAKIFGTLFYESSSSICRAAIHYGILDDKGGLVDITRNGKVPFFVKSERHGVQSLSKYKPSSSFMVSKVKVQDLDCYTTVAQLCPFEKPATHCPRIHCPAHCKDEPSYWAPVFGTNIYADTSSICKTAVHAGVISNESGGDVDVMPVDKKKTYVGSLRNGVQSESLGTPRDGKAFRIFAVRQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RM30-1", "uniprot_id": "A0A8M1RM30_DANRE", "id": "A0A8M1RM30-1", "name": "", "aln": "---------------------------------------------------------------------------------MHALVSIALLFLGVSLAASLFLPDSLELRQLMQRYQEELEPNSTKPDAPVRTRRAIEWSDREEILKLHNKLRGEVYPTASNMEYMIWDDELERSATSWAEQCQWEHGPQDLL--MSIGQNLAVHWGRYRSPA------YHVQAWYDEVKDYTYPYPHECNPWCPERCSGPMCTHYTQLVWATTNRVGCAVHVCPRMNVWGEIWENAVYLVCNYSPKGNWIGEAPYQHGRPCSQCPPSYGGVCRDNLCYKRDSERQETPEMNEVEKPQEPLQPRTTPPKPQPKPSSPKKPANAKPSSPKTTRNTYLAQNIKCETKMRDKCKGATCNRYNCPANCLNKQGKVWGTLYYDVQSSICRAAIHYGVIDNNGGLVDVTRKDSFPFFVKATKNGVESFSKYKAGNAFMVSNVQEQTIDCYATVAEICPFKSTTSHCPRVFCPANCINEPSYWAPVVGSNIYADGSSICRAAIHAGVIK-ASGGYVDLLALDKRKTYTGTLKNGIQSES-KTNREGGSFRVFAVRE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFY2-1", "uniprot_id": "Q9VFY2_DROME", "id": "Q9VFY2-1", "name": "SCP domain-containing protein", "aln": "------------------------------------------------------------------------------------MMQPSAVLLTTIMIISCEVAFACNGKIIASGITAE--------------ERSIILQEHNRLRQIVATGRYPGQPGAENMREIVWDDELAARAQKWADNCQFRHDPHRTINRFTMGQNLAIIWSTAPLDADDGDFPSRIQSWFNEVQKYSFG-----DAWSPKTG------HYSQLVWGETSLVGCGYAEYKDTSKY------NKLYVCNYGPGGNVVGYNPYEVGKPSCSTYGMKPSSRYQGLCAAPG--------------------------------------------SSPAANSVYGANTIETYEYGYNSSPSSQTANNNPPTNNINKS--------------------QFSYNQPRPKPVQTINPNPSPFNPQAAVPSASTFGGSSFGS--------ASRGGSHAYTTDPSQSAGRYKHKLEAYRPSAAEFEKS-----------VHKHTILRTYIEQNQQRQDQQQQQQQKEQDQQQ---------QQPEPSSTKKPSRGWSLLTWRG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . :* . . :. . : . .*:* .:::.: : . * * *.**. : **:** * ** .* :.*.* : ::****. *. . ::*:*::**:.*:: . . : **:*:**. *. :**. . : ****.* ** :* **: *:*... . :.** . :. : :: :. : . .: . : *:. :.:. ::. : . *: . . ** :: . .::. . .. ..:: .:: . .* . *: . * * .. :* :: :. . : *::: *.*. * : . .: ::. * ", "identical_positions": 64, "similar_positions": 136, "identity": "10.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130201-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1L020-1", "uniprot_id": "MEX3A_HUMAN", "id": "A1L020-1", "name": "RNA-binding protein MEX3A", "aln": "MPS-LVVSGIMERNGGFG-ELG--CFGGS---AKDRGLLEDERALQLALDQLCLLGLGEPPAPTAGEDGGGGGGGAPAQPAAPPQPAPPPPPAAPPAAPTAAPAAQTPQPPTAPKGASDAKLCALYKEAELRLKG-SSNTTECVPVPTSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFMVTGRREDVATARREIISAAEHFSMIRASRNKSGAAFGVAPALPGQVTIRVRVPYRVVGLVVGPKGATIKRIQQQTNTYIITPSRDRDPVFEITGAPGNVERAREEIETHIAVRTGKILEYNNENDFLAG-SPDAAIDSRYSDAWRVHQPGCKPLS-TFRQNSLGCIGECGVDSGFEAPRLGEQGGDFGYGGYLFPGYGVGKQDVYYGVAETSPPLWAGQENATPTSVLFSSASSSSSSS--AKARAGP----PGAHRSPATSAGP-ELAGLPRRPPGEPLQGFSKLGGGGLRSPGGGRDCMVCFESEVTAALVPCGHNLFCMECAVRICERTDPECPVCHITATQAIRIFS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3UYU0-1", "uniprot_id": "G3UYU0_MOUSE", "id": "G3UYU0-1", "name": "", "aln": "MPS-LVVSGIMERNGGFG-ELG--CFGGS---AKDRGLLEDERALQLALDQLCLLGLGEPPAPTAGEDGGGGGGGAPAQPAAPPQPAPPPPPAAAPAAPSAAPAAQTPQPPTAPKGANDAKLCALYKEAELRLKG-SSNTTECVPVPTSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFMVTGRREDVATARREIISAAEHFSMIRASRNKSGAAFGVAPALPGQVTIRVRVPYRVVGLVVGPKGATIKRIQQQTNTYIITPSRDRDPVFEITGAPGNVERAREEIETHIAVRTGKILEYNSDGDFLAG-SPDAALDSRYSDAWRVHAPGCKPLS-TFRQNSLGCIGECGVDSAFEAPRLSEQGGDFGYSGYLFPGYGVGKQDVYYGVAETSPPLWAGQENATPTSVLFSSASSSSSS---AKARAGP----PGAHRSPATSAGPEQLTGLPRRPPGEPLQGFSKLGTGGLRSPGSGRDCMVCFESEVTAALVPCGHNLFCMECAVRICERTDPECPVCHITATQAIRIFS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7EXM9-1", "uniprot_id": "E7EXM9_DANRE", "id": "E7EXM9-1", "name": "", "aln": "MPSLLVLAGIMEKNGGYGGDLAGSGFGSEGLLVPPEEEEDDSRALRVALGQLSLLGLGEG---EDGAPAGGGGGGGGVQDRS-----------------NNNHHNHIQAEPGMLQGKN--KLCALYESSPTETKGRGCNITECVPVPSSEHVAEIVGRQGCKIKALRAKTNTYIKTPVRGEEPVFLITGRKEDVALARREIISAAEHFSMLRASRNKFSGSP--PAPLPGQTTIQVRVPYRVVGLVVGPKGSTIKRIQQQTCTYIVTPSRDRDPVFEITGSPGNAERAREEIEAHIAFRTGGLHDHNNENDCLGPESGNGGLESRLQQVWGLQGAPRKPLASSYRQN----FSDTVVGS-----SSGGGGGIYSKGDFNNHGSSGDKPSSYFGSEGTQS--WGDPDYPKQVAYYAQQRSKSFGGLPLPLTRLSPGLPEPCGTGNSNAVGSPHAQARRAHSEPTAATGAFTGRLPVPDSPPAMSRDCMTCFESKVTAALVPCGHNLFCMECAIRICELNHPECPVCHTLVTQAIRIFS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** **::****:***:* :*. **.. . . :*.***::**.**.****** * .******. .* : . : * :* . ******:.: . ** ..* *******:*************************************::***:**** **************:****** ..: ...****.**:****************:********* ***:**************:***.********:***.*** : ::*.:.* *. * :..::** .:.* :: . ***: ::*** :.: *.* . ** :. ..: * . .* . *:* *.. *.. : .. .: .. *.* .. . :* .* * . .. : ..* : .: * . .*: .*. .****.****:******************:**** ..******* .********", "identical_positions": 262, "similar_positions": 122, "identity": "48.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130201-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXX3-1", "uniprot_id": "Z385D_RAT", "id": "Q6AXX3-1", "name": "Zinc finger protein 385D", "aln": "-MRKIMYFGGTCQSPALPALIHPPAPPLQPSLDIKPFLPFPLDTAATVNLFPNFNAMDPIQKAVINHTFGFPLPHRKKQIISCNICQLRFNSDSQAAAHYKGTKHAKKLKALES---MKNKQKSVTAKDSAKTTFTSITTNPITTSSDKTESTAGTQVIAR---SADMRKSSEVTTELTSNAEK------SLTAAVAAGNNS--SPPTETEEEKAKRLLYCSLCKVAVNSASQLEAHNSGTKHKTMLEARNGSGTIKAFPRAGMKGKGPVNK---GNTGLQNKTFHCEICDVHVNSETQLKQHISSRRHKDRASGKPPKPKYSPYNKLQK-AAHPLGVKLVFSKEPSKPLTPRILPNPLAAAAAAAAVAVNSPFSLRTAPAATLFQTSALPPALLRPAPGPIRTTHTPVLFSPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H6B1-1", "uniprot_id": "Z385D_HUMAN", "id": "Q9H6B1-1", "name": "Zinc finger protein 385D", "aln": "-MRNIMYFGGTCQSPALPALVRPPAPPLQPSLDIKPFLPFPLDTAAAVNLFPNFNAMDPIQKAVINHTFGVPLPHRRKQIISCNICQLRFNSDSQAAAHYKGTKHAKKLKALEA---MKNKQKSVTAKDSAKTTFTSITTNTINTSSDKTDGTAGTPAISTT-TTVEIRKSSVMTTEITSKVEK------SPTT--ATGNSS--CPSTETEEEKAKRLLYCSLCKVAVNSASQLEAHNSGTKHKTMLEARNGSGTIKAFPRAGVKGKGPVNK---GNTGLQNKTFHCEICDVHVNSETQLKQHISSRRHKDRAAGKPPKPKYSPYNKLQK-TAHPLGVKLVFSKEPSKPLAPRILPNPLAAAAAAAAVAVSSPFSLRTAPAATLFQTSALPPALLRPAPGPIRTAHTPVLFAPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9NZX0-1", "uniprot_id": "A0A8M9NZX0_DANRE", "id": "A0A8M9NZX0-1", "name": "", "aln": "MTMESMFIGNACQSGLVPALVRAPLPAVPSSLGMKHFVPFALDGGSALSLIPSFSSMNAVQKAVLHHTISTSAPSKRK-AMSCGVCHLRFNSQSQALAHYKGTKHAKKLKSLDAPKCLKHKSSSASRENTNKELPKGLVPSTVAYSEDRKGGDAGALVAPSSPSSAPASGPSTDSTESASVSGEEDGSSCTPVPPESEENHSGTSPESETEDEKALRLLYCSLCKVAVNSVSQLDAHNSGTKHKTMLEARSGNGSIKSFPRTGQKSKLPTDASKTADTGLQNKTFHCETCDVRVNSETQLKQHISSRRHKDRAAGKPAKPKFSPYTKTQRGASKQTQVKMPVGKDLCSPLTTRIMPSHLAAVAAAAAS-IGSTFPLRACHNPTLFQTQSLPAALLRPAPGPIRTAHTPLLFAPY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *::*.:*** :***::.* *.: .**.:* *:**.** .:::.*:*.*.:*:.:****::**:. . * ::* :**.:*:*****:*** *************:*:: :*:*..*.: ::: * ..:....: *.*:. . **: . . :. .* :** :* : : .. : * * .* :***:*** **************.***:***************.*.*:**:***:* *.* *.: .:*********** ***:********************:***.***:***.* *: ::: **: ..*: ..**:.**:*. ***.***** :.*.*.**:. .*****.:**.************:***:**:**", "identical_positions": 210, "similar_positions": 125, "identity": "50.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130201-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHF4-1", "uniprot_id": "D3ZHF4_RAT", "id": "D3ZHF4-1", "name": "", "aln": "MGCGPSQQTEDQSQSRMPSPRKGWEEGSKADVRVTSSKENYSPQTEVAWPKDTIDNAKSLDQQAQMGSLPGTIPENSPTPSNTNRRINSDPVANGLTNKPQLLESWERPKSSDILEELIVQGIIQSRSKVFRNGESYDVMVGTTEKPLRKPPARLKKLKVKKEVKDFTIQDLEEKMQAAEERRKTKKEEIRKRLRSDRLLP-TANPSDETEL-GRVEVPFTKGLPAVSAPALEKSYTQEGEPLKRKKSESDVAQMNRNYSCTGLELVESDMYYNQEDNIF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P3A1-1", "uniprot_id": "STMD1_MOUSE", "id": "Q6P3A1-1", "name": "Stathmin domain-containing protein 1", "aln": "MGCGPSQQKEDQSQSRIPSPRKGWEEGSKADVRVTSSKENCSPQTEAAWPKHTIDNAKSLDQQAQIGSLPGTIPENSPTPSKTSRRINSDPVANGLTNKPQLPESWERPKSSDILEELIVQGIIQSRSKVFRNGESYDVMVDTTEKPLRKPPARLKKLKVKKEVKDFTIQDIEEKMQAAEERRKTKKEEIRKRLRSDRLLP-TANPSDEAEPPGRVEVPFTKGLPAVNTPALEKSDVQEGEPLKRKKSESDVAQMNRNYSCTGLELVESDMYYNQEDNIF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "H3BQB6-1", "uniprot_id": "STMD1_HUMAN", "id": "H3BQB6-1", "name": "Stathmin domain-containing protein 1", "aln": "MGCGPSQPAEDR--RRVRAPKKGWKEEFKADVSVPHTGENCSPRMEAALTKNTVDIAEGLEQ-VQMGSLPGTISENSPSPSERNRRVNSDLVTNGLINKPQSLESRERQKSSDILEELIVQGIIQSHSKVFRNGESYDVTLTTTEKPLRKPPSRLKKLKIKKQVKDFTMKDIEEKMEAAEERRKTKEEEIRKRLRSDRLLP-SANHSDSAEL-DGAEVAFAKGLQRVRSAGFEPSDLQGGKPLKRKKSKCDATLIDRNESDESFGVVESDMSYNQADDIVY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RKX1-1", "uniprot_id": "A0A8M1RKX1_DANRE", "id": "A0A8M1RKX1-1", "name": "", "aln": "-MRMIEEVYPDPRTSEEPHNQRETNMGCGSSRITVVEPVKTSNLNGNETDTLQFDVAQGGSRGDSAISKMTIDSGVSLDAAEAAGLPGTVPRLLPQLQAQTPGHSEERPESSEILEQLLAQGIIPAQPKHGESGQSYNIMMDDTGKARSRPPARLESLKTRKEQEITKKEDIEMKMRLVEERRKEREEDLKRRLRIKSARPRSSAPVNSEGKLDPEELLHSEQLPVPIRTKHGES--EDHALTDSPELENDSTFQQNGDTDEGF-----------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: * . :: : :. . : * . .* *:. .: . * . * .:: .: : .* ** :**:***:*:.**** ::.* ..*:**:: : * *. :**:**:.** :*: : . :*:* **. .***** ::*::::*** . * :: :. . *: .:: * . * : . : : * : :.. : .: ", "identical_positions": 50, "similar_positions": 80, "identity": "17.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130206-12", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63744-1", "uniprot_id": "RHG07_RAT", "id": "Q63744-1", "name": "Rho GTPase-activating protein 7", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCR-----------------------DEPDTMILT--------QIEAKEACDWLRVTG---------FPQYAQLYE-DLLFPIDIALVKREHDFLDRDAIEALCRRLNTLNKCAVMKLEISPHRKRSE---------------------------------------------------------------------------------------------------DSDEEEPCAISGKWTFQRDSKRWSRLEEF--------------------------------DVFSPKQDPIP-----GSPDNSRLQS--------ATSRESMLTDLSEHQEVSSIR-----------SLSSTSSSAPTHVPH-SGEATTPRTNSVISVCSSSHFVGNEDSFSS-LPSPKELSSFSFSMKG------HEKNTKSKTR-----SLLKRMESLKLKGSHHS------------------------------------------------------KHKAPSKLGLIISAPILQEGMDE---------------------------EKLKQLNCVEISALNGNHINVPMVRKRSVSNSTQTSSS----------SSQSETSS--AVSTPSPVTRTRSLSTCN---KRVGMYLEGFDPFSQSAFNN-------------------------------------------------------------------------VTEQNYKN------RESYPEDTVFYIPEDH------------------------------KPGTFPKALSNGSFCPSGNS-SVNWRTGSFHG------------PGHLSLRRENSSD----SPKELKRRNSSSSVSSRMSIYDNVPGS--------------------ILYSSSGELADLENEDIFPELDDILYHVKGMQRIVNQWSEK---------FSDEGDSDSALDSVSPCPSSPKQIHLDVDHDRRTPSDLDSTGNSLNEPEEP----------------------------------------------------------------------------TDIPERRDSGVGASLTRCNR-HRLRWHSFQSSHRP---------------SLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRSGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESAEDY----VNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSHVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRK-QSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLSNDQPADYRHFLQDCVDGLFKEVKEKFKGWVSYPTS--EQAELSYKKVSEGPPLRLWRATIEVPAAPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPRGACALLFTSVDHDRAPVAG--VRVNVLLSRYLIEPCGSGKSKLTYMCRADLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQSTESKDTRSR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96QB1-2", "uniprot_id": "RHG07_HUMAN", "id": "Q96QB1-2", "name": "Rho GTPase-activating protein 7", "aln": "-----------------------------------------------------MSVAIRKRSWEEHVTH-WMGQPFNSDDRNTACHHGLVADSLQASM----------EKDATLNVDRKEKCVS------------------------------LPDCCHGSELRDFPGRPMG-HLSKDVDENDSHEGEDQFLSLEASTETLVHVSDEDNNADLCLTDDKQVLN--TQGQKTSGQHMIQGAGSLEKA--LPIIQSNQVSSNSWGIAGETELALVKESGERKVTDS-ISKS---------LELCNEISLSEIKDAPKVN--AVDTLN-----------------VKDIAPEKQLLNSAVIAQQRRKPDPPKDENERSTCN---------------VVQNEFLD-----------------------------------TPCTN-----------RGLPLLKTDFGSCLLQPPSCPNGMSAENGLEKSGFSQHQNKSPPKVKAEDGMQ-------------------------------------------------------------CLQLKETLATQEPTDN----------------------------QVRLRKRKEIREDRDRARLDSMVLLIMKLDQLDQDIENALSTSSSPSGTPTNLRRHVPDLESGSESGADTISVNQTRVNLSSDTESTDLPSSTPVANSG-----------------------TKPKTTAIQGISEKEKAEIEAKEACDWLRATG---------FPQYAQLYE-DFLFPIDISLVKREHDFLDRDAIEALCRRLNTLNKCAVMKLEISPHRKRSD---------------------------------------------------------------------------------------------------DSDEDEPCAISGKWTFQRDSKRWSRLEEF--------------------------------DVFSPKQDLVP-----GSPDDSHPKD--------GPSPGGTLMDLSERQEVSSVR-----------SLSSTG-SLPSHAPP-SEDAATPRTNSVISVCSSSNLAGNDDSFGS-LPSPKELSSFSFSMKG------HEKTAKSKTR-----SLLKRMESLKLKSSHHS------------------------------------------------------KHKAPSKLGLIISGPILQEGMDE---------------------------EKLKQLNCVEISALNGNRINVPMVRKRSVSNSTQTSSS----------SSQSETSS--AVSTPSPVTRTRSLSACN---KRVGMYLEGFDPFNQSTFNN-------------------------------------------------------------------------VVEQNFKN------RESYPEDTVFYIPEDH------------------------------KPGTFPKALTNGSFSPSGNNGSVNWRTGSFHG------------PGHISLRRENSSD----SPKELKRRNSSSSMSSRLSIYDNVPGS--------------------ILYSSSGDLADLENEDIFPELDDILYHVKGMQRIVNQWSEK---------FSDEGDSDSALDSVSPCPSSPKQIHLDVDNDRTTPSDLDSTGNSLNEPEEP----------------------------------------------------------------------------SEIPERRDSGVGASLTRSNR-HRLRWHSFQSSHRP---------------SLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNEGAIDC----VNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRK-QSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLGNDDSADYQHFLQDCVDGLFKEVKEKFKGWVSYSTS--EQAELSYKKVSEGPPLRLWRSVIEVPAVPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPKGACALLLTSVDHDRAPVVG--VRVNVLLSRYLIEPCGPGKSKLTYMCRVDLRGHMPEWYTKSFGHLCAAEVVKIRDSFSNQNTETKDTKSR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R0Z9-1", "uniprot_id": "RHG07_MOUSE", "id": "Q9R0Z9-1", "name": "Rho GTPase-activating protein 7", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCR-----------------------DEPDTMILT--------QIEAKEACDWLRVTG---------FPQYAQLYE-DLLFPVDIALVKREHDFLDRDAIEALCRRLNTLNKCAVMKLEISPHRKRSE---------------------------------------------------------------------------------------------------DSDEDEPCAISGKWTFQRDSKRWSRLEEF--------------------------------DVFFPKQDPIP-----GSPDNSRLQS--------ATSHESMLTDLSEHQEVASVR-----------SLSSTSSSVPTHAAH-SGDATTPRTNSVISVCSSGHFVGNDDSFSS-LPSPKELSSFSFSMKGH-----HEKNTKSKTR-----SLLKRMESLKLKGSHHS------------------------------------------------------KHKAPSKLGLIISAPILQEGMDE---------------------------AKLKQLNCVEISALNGNHINVPMVRKRSVSNSTQTSSS----------SSQSETSS--AVSTPSPVTRTRSLSTCN---KRVGMYLEGFDPFSQSTLNN-------------------------------------------------------------------------VTEQNYKN------RESYPEDTVFYIPEDH------------------------------KPGTFPKALSHGSFCPSGNS-SVNWRTGSFHG------------PGHLSLRRENSHD----SPKELKRRNSSSSLSSRLSIYDNVPGS--------------------ILYSSSGELADLENEDIFPELDDILYHVKGMQRIVNQWSEK---------FSDEGDSDSALDSVSPCPSSPKQIHLDVDHDRRTPSDLDSTGNSLNEPEEP----------------------------------------------------------------------------TDIPERRDSGVGASLTRCNR-HRLRWHSFQSSHRP---------------SLNSVSLQINCQSVAQMNLLQKYSLLKLTALLEKYTPSNKHGFSWAVPKFMKRIKVPDYKDRSVFGVPLTVNVQRSGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNESAEDN----VNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPKDQRLQAIKAAIMLLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPRVMQRK-QSLGKPDQKDLNENLAATQGLAHMIAECKKLFQVPEEMSRCRNSYTEQELKPLTLEALGHLNSDQPADYRHFLQDCVDGLFKEVKEKFKGWVSYPTS--EQADLSYKKVSEGPPLRLWRSTIEVPAAPEEILKRLLKEQHLWDVDLLDSKVIEILDSQTEIYQYVQNSMAPHPARDYVVLRTWRTNLPRGACALLLTSVDHDRAPVAG--VRVNVLLSRYLIEPCGSGKSKLTYMCRADLRGHMPEWYSKSFGHLCAAEVVKIRDSFSNQNTESKDTRSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58JHT8-1", "uniprot_id": "A0AC58JHT8_DANRE", "id": "A0AC58JHT8-1", "name": "Rho GTPase-activating protein 7", "aln": "-----------------------------------------------------MPVAIRNRSWEDHVTSPRTGLQYSYDDLDLVCCHARHRRGRCASMPECGHHHLYPQDDIGNGTKKMERILQ------------------------------KFKNETQPNCEDVKSQLLTSRDAVNEKAQLESEQDNRLLSNNVADQDELQHSALGNLQTHNGDADNKKLNKDKVSSAISLSHLVPSAEALDQTNGLGNVLKDGISLNNTVKEDCSELTHPKEETSVENTES-MVKVNVGSEKLVYEHMNVTSSITEITNKPPTSDSSADPCDNEEGHCCETSEQAILKCIKTERSSKPMSSSSTSQEDHHIPHTEDANKANLACKDCNMTPEENGDGIFKCADGDTLN-----------------------------------VGCINPHACESSQLKECGVIDIMDTWHDCSSKLQTIHEGSCPESGDDSSAQISGDGPEEPTCRGLNTRN-------------------------------------------------------------CENLTASEDLREPQPEGIYEDHQATQNTAAKDCEMVPKADGSIVKLRTRKSSHEEREKERSRLDSMVLLIMKLDQLDKEIENALS--SSLNSTPNLKRRIISDVDLETLDSAGSLSASSQSLNTPLYRSSSSLSSSGPTGTPG-----------------------ARPKNETSAVLSENDRAEIEAKEACTWLRAAG---------FPQYAQLYE-DGQFPIEISSVTRDHDFLDQDAIEALCRRLNTLNKCALMRLEITPQRKRSE---------------------------------------------------------------------------------------------------DSDEDEPCAISGRWTFQRDSKRWSRMDQLD------------------------------LDVFSPTAGDTGSFAAFLSQDEHFVRGPLQK-EGVNASVESILTDLSEQPEVGSLHSTGS--GGRGGSLSTTVPSSPATTISNANTATTTRASSVASVCSSGTSGANEDSMSDGLPSPLERGTFAFDVKPNLISSAAEKSTRSRAK-----SFLKRMESLRLRTSSNAGSKRK-------------------------------------------------KKGVPGHGRLEISGPVLKEGLDE---------------------------DKLRRLNCVDIATLDRN-----ANRNRSISYSTQTSSGS-------AGSSQSEASSGSAVSTPSPVSRARSHSTAAGSSKRGGMYLEGFDPFNFVVLQP-------------------------------------------------------------------------SEDQDVKENHQTQNKRKEPSSTDENNRRNR------------------------------QSSDNRQMEDEESRVEEGGVIFFYLPEGHKPG------------TFPKALADGGSYHGVDNTSRRPPRRGSSASLDSRMSIYDNVPFS--------------------EVGDDEDEVGEEE-----PKLEDVLERVRGLQQLVNEWPETGIGEEEEDEEEEEGDSDSALDSASPCPSSPLQNRLEETENG---SDQDSTGNPLAERDET----------------------------------------------------------------------------LSSRERCDSGVEASLTRANRTQKLRWPSFQSSHRP---------------SLSSTVLQVGCQSVLQMNLLQKYSLLKLTALLERYTPTNKHGFSWAVPKFMKRIKVRDYKDRSVFGVPLQVIVQRSGQPLPQSIQQAMRYLRSQCLDQVGLFRKSGVKSRIQALRQMNESCGAVGG-GVNYEGQLAYDVADMLKQYFRDLPEPLLTSKLSDTFLQIYQYVPKEQRLQAVRAAVLLLPDENREALQTLLCFLSDVTASVGENQMTCTNLAVCLAPSLFHLNTLRRESSSPRVMNRK-NTLGKPDQRDLNENLAATHGLAHMIQECRKLFQIPEEMSRCRNSYMEQGLSPMRMEVLAENCG--SCNYQSLLKDSIDSLLKEAKDKFKGYDSCSTP--ENAELAYKKVQDGSSLRQWKVCVDVPASAEDVLQRILREQERWDEDLLESRIVETLDHNTEVYQYVRNSMPPHPPRDHVVLRSWMTDLPKGVCTLVSVSVDHESAAVLG--VRANVLTSRYYIEPCGANKSRLAHISRIDCRGRCPEWYNKLYGHLCAAEVVRIRDTFTCLDK--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JR05-1", "uniprot_id": "A8JR05_DROME", "id": "A8JR05-1", "name": "", "aln": "MSNARELALIEKWADIATPATPNRPTLSPTSPPALHRSIVKFCCCPQRRRYNLKQAKSHGGSNKLNVNTLHARNIFVDSDFSYIDDVPRRRQDCHSDYDDCNYDSDCGGDKADDEANDIAAAPRDDGNVALILMNQRNLSEQWRQDNKGNSNSNKAATKTCAVTKSPQSGNEQQQHQQQQQQQQQQRQPTQRLSNSLQQQQQQEQQLQQQQQQQHSNKENTLSYDNNNKPHCNYCKLPDTAEPQTNSNSNSKIDSPKSSQNKMTITTATDTETATATTATATGECGLPAATSQEFVGAATEVLCNDKATLTAATPAATATTAATTPKPRIAARPTTPSRLKTVIKTTMVKRSPSHDSTATAAHVLLPHSCSSNSNSSSNNIGAHDEPRRSVRERIAAFAAGNEQQQAARQHDKVKKLTKMQCNSNTNQNNMTAEDVKSAISNSSSSSSNQLQQQQHQTLINGQAATVPAATAAATGGVAAATSGRTSAIAADTTRYKSGLSDVAANGDVDGRPTSSATTSVVATGAPSVFSTGCATMPRTRQYGSNVAAALATGATLATSATSATSSATGATSPGSHTMTADKKFLSQAAPVQGHHHHKLQFADKADSELAALDNLDLAHSLDLLDVDGEDPYGALQDYLERVKREINEVFELRKVQRLEQQLREQLEERLSQAGVQQLDELSRSTESDSGFDSSSTTATSGTPATATAAGAGAVTSGKPVTTKLRALPPPPLSPTKTTTNSMPTPPVQADDVNIWACKFLRDLDSLMAAGDKLPPHLAALAEGSGSGSASSSPTSRTAPILLSAAASAAIQSRLGKGSSSIMEHQLQQQQQQQNGLVLKPEKHATIPLQSFYLDCGRNEASPATKSNVAYMRTLSAPNGGFASGGGGGAARGSGAPALPPQSQRKSLACPPLNGQADTITPTPATHKLTNFQSALKIEEMAAAKGTAMATGESQLATTIEDLKSRRQRQLSGGDMETMLASQPMSMPKRVGINHAVLTSRNAITPPPASASSASQSAASVHSAKGSSSAGTTPGYLVDVTKKGSTSTIWTSEESILRSVGAVDEDNNSTSSSSACEEATGVLSSGKSGISLDSSGLDNDNNESGIGTATPPKDMSHYWKSHHLQHHHHHHHRKCTGSAQDNESVSSLEALRKMKFQKSGSVASSDDPDVLEVLSQCGSGGEANESQDDMLDEEKDKMSKSQDYDEIWDCDCTDGDASSASGGGGVTATPVILRRKYTAPPPILVPRTQRSHSLDHYHSPQPLVHPRKVLPIHHHALKSKERGQLSLVLRQEPFQSLLSPSATAANQLHHFVELPSPSSASLHSGLGDSGGIQELCTKSNSAPMLLKEREMSRRFDNFEAQHLTLRYSRSQSDRYLAEIEAVEACKWLRAAGFPQYAQMYEDHQFPIDLNNVAKDHTNLENDQLQSLYRRLCVLNRCATMRLDQSHKPQTPQQKEESDDENFALSEHWTFQPHIRRWSRIGEMGLELPPPGLLSLNVEKTESSSKESSPDRFEEDGAGITLVTPGCSKAGGIPNDGSSLGEGSDSGRLRRSGSERIKDQAKALLRRVESIKSRRRKRQNRENVVISGPTVLDLSQFGQRSSLRKPDAVYSTPPSPSALSPMHTFPKAPFFGNDLKVPSHSDNFLSPNR-SSPKRTPTTPRSMRTSPLHFFSSPMSQLKEGKSDDSSSYYSDSQESSTGGKLSLRKPSKARRFLQRTGKVDDIGAHSDSECHQGRKLLIKDANSNTTEVKVKKLTRGGSLNLGKDPKKRDGFRSSSFRSRSTSRKEAKNDEDTAGATTNGGSKRQPVVRWHSFQMEERPNMIFRKCFSKKIEPLQEDAGGMPFAAMSAGQLQIIRKLALVTLTGHMERYCPSHRSGWNWELPKFIKKIKMPDYKDKKVFGVPLLMILQRSGQTLPLAVRAAFRWLQLNALDQVGIFRKSGGKSRIMKLREQIEVTDSTAECMDVFDLQQAYDVADMLKQYFRELPESLLTTKMSETFVAIFQHLPAEVRLDAVQCAVLLLPDENREILYVLLEFLTIVAANSQQNQMTSNNLGVCLAQSIFHSSISTGSASVSASPRRKGKGSGMPDMKELAEAKASHECLSFMIEHYKQIYTAAKEKLSKCNFSYMEESKPLPLEALG--EGMQFHNWRGYLYECTSATIKEGREKTRGWFSINSLNDSSVDIAYKKVGDGHPLRLWRCSTEIEGPPKEVLEFVIKQRASWDTNLLQCQTVKKLDDRTEIYQYALDGQLTT---DFCVLRSWQTDLPRGACVIVETSIDHAKAKPLFGAVRGVVLASRYLIEPCGSGRSRVMHLARVDVKGKTPEWYNKNYGHICSHYLSRIRLAFKHVADGPESKV--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... : ** :** . *: * * * . . . : ..* :* * .* : ...::*. :: ::::.: . :* .* .* :*: : :::: *: . * .: : . * *:::: ...:: ::. * .: .. . .* *: **. *::* . ..* : . : . : .:. . :: * *: :..:::: * ... : : :*:. *: :: : : : . :: * : :::. .* *.:* .:. .. : . : * . : . ** *. : : .. :.. ... .. :. : .* . * . * .* : * * * : . :** * : . . . . *: . :: .: * . . .. *.*. *. *. : : : . *: .***. * . . . : *:. :: .:* :** *** ..** . .: : . . *. *:::::* :*:.**. :*:* *::: *:.* :***:*:**: ****:.****** : :**:**.** ::: *:*:*: :.*****:***** **** **: * :: * *************:***.*:*.*:*:**: *:*::* : **:*::.*::******** * .** **: *:* :**** .**.**** *:** . . * . .** : * ** ::* * *: . *:.** . :::: .:* * : .*: :*.*. . ::: * :. .. :** ::* :*: * : ...:::**** :* .** *: :: . .:::*: ::::: ** :**:.: :: ** .**:***. :. . *. ***:* *:**:*.*.:: .*:** * ** ** *** *****..:*:: ::.* * :*: ****.* :**:*: : :** :*. ", "identical_positions": 267, "similar_positions": 359, "identity": "11.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130206-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M2BI98-1", "uniprot_id": "A0A8M2BI98_DANRE", "id": "A0A8M2BI98-1", "name": "", "aln": "----------------------------------MFFQKIFLQHIKLSHSKKRETEIFFHGFVIMRTGEFNAETACHSEGEDTHRGFKMAVFVVLLLAVMPLDVEPATTEKHSLYYIYTALSRPVNLPGIHEFTAMGLLDDRQIDYYNSQ--DQKKIPKQHWMKEKMQEDYWEKGTQSRKSKEQWFNVNVNILMDRMR------------HNKSDLHVLQWRHGCEIDSQDDDVRFSKGIDEYSYDGENFLSFDDADSQWVAPVD-----AALPTKRKWDNVPILNQYTKGYLEKECVDWLNKFREYGNEELREGSPPDVHVFARSIINGKAKLKLTCLATGFYPKDVYLTIRKYRMALLDKDLESSGVRPNHDGTFQLRMSTYIYEDEKAEYDCYVKHRTLGAPIIKKWDGKCSDCSKVTFLGMIVGAI----IGAVFVLTVIGLVILVLTRKKGIGDNDPSAIPLNNNQHIEPSVKESKNKPTAAEGQSTGGDLKS----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25311-1", "uniprot_id": "ZA2G_HUMAN", "id": "P25311-1", "name": "Zinc-alpha-2-glycoprotein", "aln": "------------------------------------------------------------------------------------MVRMVPVLLSLLLLLGPAVPQENQDGRYSLTYIYTGLSK--HVEDVPAFQALGSLNDLQFFRYNSK--DRKSQPMGLWRQVEGMED-WKQDSQLQKAREDIFMETLKDIVEYYN------------DSNG-SHVLQGRFGCEIENN----RSSGAFWKYYYDGKDYIEFNKEIPAWVPFDP-----AAQITKQKWEAEPVYVQRAKAYLEEECPATLRKYLKYSKNILDRQDPPSVVVTSHQAPG--EKKKLKCLAYDFYPG--KIDVHWTRAGEVQEPELRGDVLHNGNGTYQSWVVVAVPPQDTAPYSCHVQHSSLAQPLVVPWEAS-----------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6MG05-1", "uniprot_id": "Q6MG05_RAT", "id": "Q6MG05-1", "name": "", "aln": "--------------------------------------------------------------------------------------------MWSLIFCFLSHPQDTGARSHSLHYSYSAVTEP--GPGVPAFFASGFVDNQTFIHYDSR--KMEAEPCADWLR--ENPYYFDEETQVFTNQMKIFQLSLRNIQQYYNSSGDRSHRADGFHQQAGPHTLQFTYGCEMQGNR-----TTGHWQYGYDGRDYLTLDLDSMQYTAATF-----IAGYTKHKWQNNEYWLEREKTYLEKECVLWLKRYLTMGGENFTRTDPPQTTVTHHPRPE--GDVTLRCWALGFYPADITLTWQLNGEDL-TQDMELVETRPTGDGTFQKWAAVVVPLGKEQKYTCHVEHEGLPEPLTQRWEA-PPGTDSNMGINVIAVF--------FKLWPSLQ-------------------LWPSS---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K8A4-1", "uniprot_id": "A0A0G2K8A4_RAT", "id": "A0A0G2K8A4-1", "name": "", "aln": "--------------------------------------------------------------------------------------------MWALIFWFLTHPQETGARSHSLHYSYSAVTEP--GPGVPAFFASGFVDNQPFIHYDSR--KMEAEPCADWLR--ENPYYFDEETQVFTNRMKIFQLSLRNIQQYYNSSGDRSQRADGFHQQAGPHTLQFTYGCEMQDNR-----TTGHWQYGYDGRDYLTLDLDSMQYTAATF-----IAGYTKHKWQNNEYWLEREKTYLEKECVLWLKRYLTMGGENFTRTDPPQTTVTCHPRPE--GDVTLRCWALGFYPADITLTWQLNGEDL-TQDMELVETRPAGDGTFQKWASVVVPLGKEQKYTCRVEHEGLPEPVSLTWEP-LQLTTSKTEVCARGRWG----LQATTLCVLMV-------------------FWAWC---------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LC63-1", "uniprot_id": "A0ABK0LC63_RAT", "id": "A0ABK0LC63-1", "name": "Ig-like domain-containing protein", "aln": "--------------------------------------------------------------------------------------------MWSLIFCFLSHPQDTGARSHSLHYSYSAVTEP--GPGVPAFFASGFVDNQPFIHYDSR--KMEAEPCADWLR--ENPYYLADETQVFTNWMKTLQLSLRNIQQYYNSSGDRSQRADGFHQQAGPHTLQFTYGCEMQDNR-----TTGHWHYGYDGRDYLTLDLDSMQYTAATF-----IAGYTKHKWQNNEYWLEREKTYLEKECVLWLKRYLTMGGENFTRTDPPRTTVTHHPRPE--GDVTLRCWALGFYPADITLTWQLNGEDL-TQEMELVETRPAGDGTFQKWASVVVPSGEEQKYTCRVEHEGLPEPLTLRWDS-SLLTVVLGAVAITGAVA----IIAAVIIPAVVTV---VRRRRRNTGRKGQGLFPLSFL-------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AQ52-1", "uniprot_id": "A0A8I6AQ52_RAT", "id": "A0A8I6AQ52-1", "name": "", "aln": "------------------------------------------------------------------------------MRMLPPAY-------LLQLLAGTMVLTQT--SSHSLRYFYTALSRP--GLGEPRFIVVGYVDDTQFVRYDSDVENPRMEPRARWMEQ-EEPAYWERETRKARDTGRNFKVNLRTLLRYYN------------QSDDESHTLQWMYGCDVGPDG---HLLRGYCQEAYDGRDYISLNEDLRSWTATDM-----ASQASKIKS-EEVGEAHHQRAYLQGPCVEWLHTYLHLGKETLLRSDPPKAHVTLHPRPE--GDVTLRCWALGFYPADITLTWQLNGEDL-TQDMELVETRPAGDGTFQKWAAVVVPSGEELKYTCHVEHEGLPEPLALRW---EPSPFTDSSMPVIVVLGAVAIIGAVAIIGAVAIIGAVVRRRKRNTGEKGSYAHVLGSKAFQISDWPQKA--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06339-1", "uniprot_id": "HA15_MOUSE", "id": "P06339-1", "name": "H-2 class I histocompatibility antigen, D-37 alpha chain", "aln": "--------------------------------------------------------------------------------MLLFAH-------LLQLLVSATVPTQS--SPHSLRYFTTAVSRP--GLGEPRFIIVGYVDDTQFVRFDSDAENPRMEPRARWIEQ-EGPEYWERETWKARDMGRNFRVNLRTLLGYYN------------QSNDESHTLQWMYGCDVGPDG---RLLRGYCQEAYDGQDYISLNEDLRSWTANDI-----ASQISKHKS-EAVDEAHQQRAYLQGPCVEWLHRYLRLGNETLQRSDPPKAHVTHHPRSE--DEVTLRCWALGFYPADITLTWQLNGEEL-TQDMELVETRPAGDGTFQKWAAVVVPLGKEQYYTCHVYHEGLPEPLTLRW---EPPPSTVSNMVIIAVL---VVLGAVIILGAVVAF---VMKRRRHIGVKGCYAHVLGSKSFQTSDWPQKA--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZMP3-1", "uniprot_id": "A0A8I5ZMP3_RAT", "id": "A0A8I5ZMP3-1", "name": "", "aln": "MEPKSFRFPWKTLTAPNKSGSLKQEPPNPGPSARTLTTLWQFSLPLGAVNPVNQSASSWYRSYKVHAARGTQTGPGSQMGAMAPRT-------LLLILAAALAPTQTRAGSHSMRYFDIAVSRP--GLGEPRFIIVGYVDDTEFVRFDSDAEKPRYEPRAPWMEP-EGPEYWEEQTRRAKEGEQTFRVNLRTALHYYN------------QSEDRSHTIQRLSGCDVGSDG---RLLRGYEQYAYDGRDYIALNEDLKTWTAADF-----AARISRNKW-DQAGVAERLRAYLEGECVEWLRRYLELGKETLLRSDPPKAHVTLHPRPE--GDVTLRCWALGFYPADITLTWQLNGEDL-TQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCRVEHEGLPEPLSQRW---EPPPSTDSNMETTVIY---VVLGAVAIIAAVIIG-AVVTVVRKRRRNTG----TDSSQSSDVSLPDCKA--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P01898-1", "uniprot_id": "HA10_MOUSE", "id": "P01898-1", "name": "H-2 class I histocompatibility antigen, Q10 alpha chain", "aln": "------------------------------------------------------------------------------MGAMAPRT-------LLLLLAAALAPTQTQAGSHSMRYFETSVSRP--GLGEPRFIIVGYVDDTQFVRFDSDAETPRMEPRAPWMEQ-EGPEYWERETQRAKGNEQSFHVSLRTLLGYYN------------QSESGSHTIQWMYGCKVGSDG---RFLRGYLQYAYDGRDYIALNEDLKTWTAADV-----AAIITRRKW-EQAGAAEYYRAYLEAECVEWLLRYLELGKETLLRTDPPKTHVTHHPGSE--GDVTLRCWALGFYPADITLTWQLNGEEL-TQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCHVYHEGLPEPLTLRW---EPPPSTDS-IMSHIAD---LLWPSLKLWWYL----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P79568-1", "uniprot_id": "P79568_MOUSE", "id": "P79568-1", "name": "", "aln": "---------------------------------------------------------------------------------MALTT-------LLLLVAAALTLIETRAGPHSLRYFHTAVSWP--GLVEPRFIIVGYVDNKQFVRFDSDAENPRMEPRARWMEQ-EGPEYWERETQKAKGHEESFRVSLRTAQRYYN------------QSKGGSHTLQWMYGCDVGSDE---RLLRGYLQFAYEGRDYIALNEDLKTWTAADM-----AAQITLHKW-EQAGIAERDRAYLEGACVQSLRRYLQLRKETLLCTDPPKAHVTHHPRSY--GAVTLRCWALGFYPADITLTWQLNGEEL-TQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCHVNHEGLPEPLTLRW---EPPPSTVSNMANVAIL---VVL--VAWPSLELWW-IL----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14430-1", "uniprot_id": "HA18_MOUSE", "id": "P14430-1", "name": "H-2 class I histocompatibility antigen, Q8 alpha chain", "aln": "---------------------------------------------------------------------------------MALTM-------LLLLVAAALTLIETRAGPHSLRYFHTAVSWP--GLVEPRFIIVGYVDDTQFVRFDSDAENPRMEPRARWMEQ-EGPEYWERETQKAKGHEESFRVSLRTAQRYYN------------QSKGGSHTLQWMYGCDVGSDE---RLLRGYLQFAYEGRDYIALNEDLKTWTAADM-----AAQITLHKW-EQAGIAERDRAYLEGACVQSLRRYLQLRKETLLCTDPPKAHVTHHPRSY--GAVTLRCWALGFYPADITLTWQLNGEEL-TQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCHVNHEGLPEPLTLRW---EPPPSTVSNMANVAIL---VVL--VAWPSLELWW-IL----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14429-1", "uniprot_id": "HA17_MOUSE", "id": "P14429-1", "name": "H-2 class I histocompatibility antigen, Q7 alpha chain", "aln": "---------------------------------------------------------------------------------MALTM-------LLLLVAAALTLIETRAGQHSLQYFHTAVSRP--GLGEPWFISVGYVDDTQFVRFDSDAENPRMEPRARWMEQ-EGPEYWERETQIAKGHEQSFRGSLRTAQSYYN------------QSKGGSHTLQWMYGCDMGSDG---RLLRGYLQFAYEGRDYIALNEDLKTWTAVDM-----AAQITRRKW-EQAGIAEKDQAYLEGTCMQSLRRYLQLGKETLLRTDPPKAHVTHHPRSY--GAVTLRCWALGFYPADITLTWQLNGEEL-TQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCHVNHEGLPEPLTLRWGRWEPPPYTVSNMATIAVV---VDLGAVAIIGAVVAF-VMNRR-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P01901-1", "uniprot_id": "HA1B_MOUSE", "id": "P01901-1", "name": "H-2 class I histocompatibility antigen, K-B alpha chain", "aln": "---------------------------------------------------------------------------------MVPCT-------LLLLLAAALAPTQTRAGPHSLRYFVTAVSRP--GLGEPRYMEVGYVDDTEFVRFDSDAENPRYEPRARWMEQ-EGPEYWERETQKAKGNEQSFRVDLRTLLGYYN------------QSKGGSHTIQVISGCEVGSDG---RLLRGYQQYAYDGCDYIALNEDLKTWTAADM-----AALITKHKW-EQAGEAERLRAYLEGTCVEWLRRYLKNGNATLLRTDSPKAHVTHHSRPE--DKVTLRCWALGFYPADITLTWQLNGEEL-IQDMELVETRPAGDGTFQKWASVVVPLGKEQYYTCHVYHQGLPEPLTLRW---EPPPSTVSNMATVAVL---VVLGAAIVTGAVVAF-VMKMRRRNTGGKGGDYALAPGSQTSDLSLPDCKVMVHDPHSLA-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14427-1", "uniprot_id": "HA14_MOUSE", "id": "P14427-1", "name": "H-2 class I histocompatibility antigen, D-P alpha chain", "aln": "---------------------------------------------------------------------------------MAPRT-------LLLLLAAALAPTQTRAGPHSLRYFVTAVSRP--GLGKPRYMEVGYVDNTEFVRFDSDAENPRMKPRVRWMEQ-EGPEYWEQETQNAKDHEQSFRVSLRNLLGYYN------------QSKGGSHTIQGMRGCDVGSDW---RLLRGYEQFAYDGPDYIALNEDLKTWTAADM-----AAQITRRKW-EQAGAAETLRAYLEGACVEWLRRYLELGNATLLCTDPPKAHVTHHPRSE--GKVTLRCWALGFYPADITLTWQLNGEEL-TQDMELVETRPAGDGTFQKWAALVVPLGKEQNYTCHVEHEGLPEPLTLRW---EPPPSTDSYMVIVAVL---VVLGAVFIIGAVVAF-VMMMRR-NTGGKGGDYTLAPGSQSSEMSLRDCKVMVHDSHSLA-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P01897-1", "uniprot_id": "HA1L_MOUSE", "id": "P01897-1", "name": "H-2 class I histocompatibility antigen, L-D alpha chain", "aln": "------------------------------------------------------------------------------MGAMAPRT-------LLLLLAAALAPTQTRAGPHSMRYFETAVSRP--GLGEPRYISVGYVDNKEFVRFDSDAENPRYEPQAPWMEQ-EGPEYWERITQIAKGQEQWFRVNLRTLLGYYN------------QSAGGTHTLQWMYGCDVGSDG---RLLRGYEQFAYDGCDYIALNEDLKTWTAADM-----AAQITRRKW-EQAGAAEYYRAYLEGECVEWLHRYLKNGNATLLRTDSPKAHVTHHPRSK--GEVTLRCWALGFYPADITLTWQLNGEEL-TQDMELVETRPAGDGTFQKWASVVVPLGKEQNYTCRVYHEGLPEPLTLRW---EPPPSTDSYMVIVAVL---GVLGAMAIIGAVVAF-VMKRRR-NTGGKGGDYALAPGSQSSEMSLRDCKA--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P01889-1", "uniprot_id": "HLAB_HUMAN", "id": "P01889-1", "name": "HLA class I histocompatibility antigen, B alpha chain", "aln": "------------------------------------------------------------------------------MLVMAPRT-------VLLLLSAALALTETWAGSHSMRYFYTSVSRP--GRGEPRFISVGYVDDTQFVRFDSDAASPREEPRAPWIEQ-EGPEYWDRNTQIYKAQAQTDRESLRNLRGYYN------------QSEAGSHTLQSMYGCDVGPDG---RLLRGHDQYAYDGKDYIALNEDLRSWTAADT-----AAQITQRKW-EAAREAEQRRAYLEGECVEWLRRYLENGKDKLERADPPKTHVTHHPISD--HEATLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDRTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWE--PSSQSTVPIVGIVAGL---AVLAVV-VIGAVVAA--VMCRRKSSGGKGGSYSQAACSDSAQGSDVSLTA--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10321-1", "uniprot_id": "HLAC_HUMAN", "id": "P10321-1", "name": "HLA class I histocompatibility antigen, C alpha chain", "aln": "------------------------------------------------------------------------------MRVMAPRA-------LLLLLSGGLALTETWACSHSMRYFDTAVSRP--GRGEPRFISVGYVDDTQFVRFDSDAASPRGEPRAPWVEQ-EGPEYWDRETQKYKRQAQADRVSLRNLRGYYN------------QSEDGSHTLQRMSGCDLGPDG---RLLRGYDQSAYDGKDYIALNEDLRSWTAADT-----AAQITQRKL-EAARAAEQLRAYLEGTCVEWLRRYLENGKETLQRAEPPKTHVTHHPLSD--HEATLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGQEQRYTCHMQHEGLQEPLTLSWE--PSSQPTIPIMGIVAGL---AVLVVLAVLGAVVTA--MMCRRKSSGGKGGSCSQAACSNSAQGSDESLITCKA-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04439-1", "uniprot_id": "HLAA_HUMAN", "id": "P04439-1", "name": "HLA class I histocompatibility antigen, A alpha chain", "aln": "------------------------------------------------------------------------------MAVMAPRT-------LLLLLSGALALTQTWAGSHSMRYFFTSVSRP--GRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAPWIEQ-EGPEYWDQETRNVKAQSQTDRVDLGTLRGYYN------------QSEAGSHTIQIMYGCDVGSDG---RFLRGYRQDAYDGKDYIALNEDLRSWTAADM-----AAQITKRKW-EAAHEAEQLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISD--HEATLRCWALGFYPAEITLTWQRDGEDQ-TQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRWE--LSSQPTIPIVGIIAGL---VLLGAV-ITGAVVAA--VMWRRKSSDRKGGSYTQAASSDSAQGSDVSLTACKV-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17693-1", "uniprot_id": "HLAG_HUMAN", "id": "P17693-1", "name": "HLA class I histocompatibility antigen, alpha chain G", "aln": "------------------------------------------------------------------------------MVVMAPRT-------LFLLLSGALTLTETWAGSHSMRYFSAAVSRP--GRGEPRFIAMGYVDDTQFVRFDSDSACPRMEPRAPWVEQ-EGPEYWEEETRNTKAHAQTDRMNLQTLRGYYN------------QSEASSHTLQWMIGCDLGSDG---RLLRGYEQYAYDGKDYLALNEDLRSWTAADT-----AAQISKRKC-EAANVAEQRRAYLEGTCVEWLHRYLENGKEMLQRADPPKTHVTHHPVFD--YEATLRCWALGFYPAEIILTWQRDGEDQ-TQDVELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPLMLRWK--QSSLPTIPIMGIVAGL---VVLAAV-VTGAAVAA--VLWRKKSSD--------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P30511-1", "uniprot_id": "HLAF_HUMAN", "id": "P30511-1", "name": "HLA class I histocompatibility antigen, alpha chain F", "aln": "---------------------------------------------------------------------------------MAPRS-------LLLLLSGALALTDTWAGSHSLRYFSTAVSRP--GRGEPRYIAVEYVDDTQFLRFDSDAAIPRMEPREPWVEQ-EGPQYWEWTTGYAKANAQTDRVALRNLLRRYN------------QSEAGSHTLQGMNGCDMGPDG---RLLRGYHQHAYDGKDYISLNEDLRSWTAADT-----VAQITQRFY-EAEEYAEEFRTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISD--HEATLRCWALGFYPAEITLTWQRDGEEQ-TQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWE--QSPQPTIPIVGIVAGL---VVLGAV-VTGAVVAA--VMWRKKSSDRNRGSYSQAAV---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P13747-1", "uniprot_id": "HLAE_HUMAN", "id": "P13747-1", "name": "HLA class I histocompatibility antigen, alpha chain E", "aln": "---------------------------------------------------------------------------------MVDGT-------LLLLLSEALALTQTWAGSHSLKYFHTSVSRP--GRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPWMEQ-EGSEYWDRETRSARDTAQIFRVNLRTLRGYYN------------QSEAGSHTLQWMHGCELGPDG---RFLRGYEQFAYDGKDYLTLNEDLRSWTAVDT-----AAQISEQKS-NDASEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISD--HEATLRCWALGFYPAEITLTWQQDGEGH-TQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPEPVTLRWK--PASQPTIPIVGIIAGL---VLLGSV-VSGAVVAA--VIWRKKSSGGKGGSYSKAEWSDSAQGSESHSL---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P14432-1", "uniprot_id": "HA1T_MOUSE", "id": "P14432-1", "name": "H-2 class I histocompatibility antigen, TLA(B) alpha chain", "aln": "----------------------------------------------------------------------------MRMGTPVPGT-------LLILLAASQGQTQTCPGSHSLRYFYTALSRP--AISEPWYIAVGYLDDTQFVRFNSSGETATYKLSAPWVEQ-EGPEYWARETEIVTSNAQFFRENLQTMLDYYN------------LSQNGSHTIQVMYGCEVEFFG---SLFRAYEQHGYDGPDYIALNEDLKTWTAADT-----AAEITRSKW-EQAGYTELRRTYLEGPCKDSLLRYLENRKKTQECTDPPKTHVTHHPRPE--GYVTLRCWALRFYPADITLTWQLNGEEL-IQDTELVETRPAGDGTFQKWAAVVVPLGKEQKYTCHVYHEGLPEPLTLRWE---PPQTSMPNRTTVRAL-----LGAMIILGFMSGS-VMMWMRKNNGGNGDDNTAAYQNEREHLSLDPRAESEALGVEAGMKDLPSAPPLVS-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6W9J5-1", "uniprot_id": "Q6W9J5_RAT", "id": "Q6W9J5-1", "name": "", "aln": "--------------------------------------------------------------------------METSAILT-----------LHLLLSASLALTQSFKGSHSLRYFDIAVSRP--GLEETHYMTLGYVDDTEFVHFNNEAVNPRFEPRVPWMEQ-MGQKYWDDQTRIAKVAEQQIRVYFQKLRGYYN------------QSQNSSHTIQRMTGCYIGPDG---HLLHAYRQFGYDGQDYLTLNEDLSTWTAADS-----AAEITHREW-KATNEAEFWRVYLEGPCMVWLFKYLTVGNETLLRADPPKVYVTHHPRPE--GDITLRCWALGFYPSDITLIWQRDGEDL-TQDMDVIETRPAGDGTFQKWAAVVVPSGKEQNYTCYVEHEGLPEPLTLRWS--RPPQS---FIPTIVVA-----VGLVLLGASVVTL--VIWKKSSGGGRG--------------------------------------------SLRFLSN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6W9L1-1", "uniprot_id": "Q6W9L1_MOUSE", "id": "Q6W9L1-1", "name": "", "aln": "--------------------------------------------------------------------------METSAFFTLLFT-------LYLLLGASLALAQTFKGSHSLRYFDIAVSRP--GLEETHYMTVGYVDDTEFVHFDNEAENPRFEPRVPWMEQ-MGQKYWDDQTRIAKAAEQQIRVYFQKLRDYYN------------QSQNSSHTIQRMTGCYIGPDG---HLLHAYRQFGYDGQDYLTLNEDLSTWTAADA-----AAEITRREW-EATNVAEFWRVYLEGPCMVWLFKYLTVGNETLLRTEPPKAYVTHHPRPE--GDVTLRCWALGFYPSDIIMIWQRDGEDQ-TQDMDVIETRPAGDGTFQKWVAVVVPSGKEQNYTCHVAHEGLPEPLTLRWS--RPPQS---FIFIIIVA-----VGLVLLGASVATL--VMWKKSSGGERG--------------------------------------------SL-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6MG01-1", "uniprot_id": "Q6MG01_RAT", "id": "Q6MG01-1", "name": "", "aln": "----------------------------------------------------------------------MLWVPKAAARWLSALL-------QILLLNACFSWTWTLVGSHSLRYFSTVMSWP--GLREPRIIVSGYIDNMEFLRLDSDAETPRVKPLVPWLEQ-EGLEYLEQQIHRIRTQAQQSERNLMTLVRFYN------------KSMDDFHTLQWQQGCDVGSDG---RLLHWYDQLAFDGIDHPTLNKDLRFWTAWTST----VAQISQPEL-EAR---------LKDNCSELLQKYPEKEKERLLRSDPPRAHVTRHPRPE--SDVTLRCWALGFYPADITLTWQLNGEDL-IQEMEFVETRPAGDGTFQKWASVVVPLGKEQKYTCLVEHEGLSEPLTLRWE--PAQDSTTTIILIILPT-----VSAIALCVAAVAT--CICLKKKAGERGRHDTQEADGDSPQDSSKIVVDDQEMEDPFWNTENYRTHLGYRSGTLGFLSLSP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I5ZYQ2-1", "uniprot_id": "A0A8I5ZYQ2_RAT", "id": "A0A8I5ZYQ2-1", "name": "Ig-like domain-containing protein", "aln": "------------------------------------------------------------------------------MRNPIPSTLLLLLLLLLLLLLATLDRTGYCAGSHWLQTFNTVILEP--GMTEPRLIQVSYVDSIQFQGFDSQAPNASMQPRAAWIEQ-EPPEYWEKETTQVVSLTLSKGRILRYIANENR------------HSRN------------------------GNYRLTYYDYDYVTLNEDMISWRAEGE-----IAKRWLSIW-ETEGVGESWMTYLRGTCSERLLRFLELGKKTLLRSDAPKTHLTHQVRPD--GNVTLRCWALGFYPADITLTWQRDGKNH-TQDMELPDTRPAGDGTFQKWAAVMVPSGEEQRYTCHVHHEGLPEPLTLKW---EPS-TTIPIVAILIGLI-----VVTLVIGTVVIL--RVWKK------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0L3Q2-1", "uniprot_id": "A0ABK0L3Q2_RAT", "id": "A0ABK0L3Q2-1", "name": "Ig-like domain-containing protein", "aln": "------------------------------------------------------------------------------MRNLIPST----LLLLLLLLLATLDRTGYCAGSHWLQTFNTVILEP--GMTEPRLIQVSYVDSIQFQGFDSQAPNASMQPRAAWIEQ-EPPEYWEKETTQVVSLTLSKGRILRYIASGNR------------HSKNDYRTLQEVFGCNLANDG---TFLRGDYRLTYYDYDYVTLNEDMISWSAEGE-----IAKSLLSIW-ETGGVGESWMTYLRGTCSERLLRFLELGKKTLLRSDAPKTRLTHQVRPD--GNVTLRCWALGFYPADITLTWQRDGINH-TQDMELPDTRPAGDGTFQKWAAVMVPSGEEQRYTCHVHHEGLPEPLTLKW---EPS-TTIPIVAILIGLI-----VVTLVIGTVVYL--VVQKK------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O19443-1", "uniprot_id": "O19443_MOUSE", "id": "O19443-1", "name": "", "aln": "------------------------------------------------------------------------------MRNTGPCT-------LLLLLMVALDLNHYCAGSHWLQTFNIVILEP--GMLEPRFIQVSYVDSIQYQGFDSKDPSAGMQPRAAWIEL-EPPEYWEKETSRVLELSQVERQVLRLMVKKNG------------HKMDGYHTLQEVYGCNVANDG---SFLGGHYRLTYYGYDYLTLNEDLSSWTAEGK-----GAQHAKSRW-EDAGEAKRRKTYLQGECVQRLLRYLDLGKETLLCSDAPQTHVTHHVRPE--GNVTLRCWALGFYPADITMTWKRDGNNL-TQDMELPDTRPAGDGTFQKWAAVVVPSGEELRYTCHVHHEGLPEPLTLKW---EPP-HTIPIIAILIGLV-----LGTLVVGTVVIF--LVWRK------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GK27-1", "uniprot_id": "A0A8I6GK27_RAT", "id": "A0A8I6GK27-1", "name": "", "aln": "---------------------------------------------------------------------MCLFPLATIMKTFVTEA-------LLLLLLAVLALASHPEGSHLFGLFQTLLTRP--GHSEPLFISAGFMDNIQFERFNNRSDFPGMEHCAPWIDH-RSPEYWKEHTQRALKDIRFMRQALKLMIHTYN------------YSATGYHTIQRRIGCHVLPRG---YFSHGFLELAFNGQDYIMLNEDLRTWTTVGK-----AAEILRKEW-EKHSFAQAMKIYLEVSCVDSFLTELAYGKEILLRIDPPKVQVIRKVRLN--RKITLMCWALSFYPPEITLTWQRDGCNQ-MQDMEVVETRPAGDGTFQKWAAVVVSSGEEQRYTCHVNHKGLPEVITMRW---EPPEPIIPITTIVIAVV-----LGALVVGAVMTF--LIWKMTRGKERAWF---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AHD5-1", "uniprot_id": "A0A8I6AHD5_RAT", "id": "A0A8I6AHD5-1", "name": "", "aln": "------------------------------------------------------------------------------MKVLLVLA-------VLLLMVT-LVITKNPKGSHSLRYLQTLLSWP--GLAEPQFIFVGYVGNTQFIGFNSRSQSQWSLHRAPWKDQ-QTPEYWEKTIQEVLSEKRNLKEVMEKMLHIYP------------NSTTGNHTIQMRYGCDVLPGG---YFSHGILELNFDSQDYIILNDELHNWIIDGK-----AAEMLKQEW-EDTHYAQIVKNYLKGSCVDELLTELDLGKDYLLRTDTPRTHVIHKVRPD--RKIILRCWALNFYPAEITITWQRDGRNQ-TQDVEVIETRPAGDGTFQKWAAVVVPSGEEQKYTCRVEHEGLPEPITLRW---ESPQSTIPVMAIVLCLV-----LGALLTGAVVTS--LIWKR---KIKG-----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0L3I7-1", "uniprot_id": "A0ABK0L3I7_RAT", "id": "A0ABK0L3I7-1", "name": "", "aln": "------------------------------------------------------------------------------MGSSVFSV------LLPLLLSRAWALNQVGAGIHSLQFFATAVTQP--SSREHSFIFVGFVDDTQFLCYNNQGESQRMEPRALWVKN-MGPGYWERQTRMVKDISKNSLVNLREAMSVYN------------HSEDGTHVFQCVSGCDVGPDG---LFLRGHEQHAYDGRDYLALNKDLHSWTAGDT-----AAQITRRKW-EEAGVAEQRRTYLKGECVESLRTYLEIGKETLLGADPPKAHVTHHPSPE--GDNTLRCWALGFYPSDITLTWQRDGEDL-TQDMELVETRPGGDGTFQKWAAVVVPSGEEHRYTCCVEHEGLTEPLLLKW---DPSKHTIPIMGITAGLVF----LGVAFTGAVVAI--AMRKQRGSHTVPRLGWNSLCSCGGESSLSA-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q30201-1", "uniprot_id": "HFE_HUMAN", "id": "Q30201-1", "name": "Hereditary hemochromatosis protein", "aln": "------------------------------------------------------------------------------MGPRARPA------LLLLMLLQTAVLQGRLLRSHSLHYLFMGASEQ--DLGLSLFEALGYVDDQLFVFYDHE--SRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHN-------------HSKESHTLQVILGCEMQEDN---S-TEGYWKYGYDGQDHLEFCPDTLDWRAAEP-----RAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTS---SVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWE---PSPSGTLVIGVISGIA------VFVVILFIGILFIILRKRQGSRGAMGHYVLAERE--------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q29980-1", "uniprot_id": "MICB_HUMAN", "id": "Q29980-1", "name": "MHC class I polypeptide-related sequence B", "aln": "---------------------------------------------------------------------------------MGLGR-----VLLFLAVAFPFAPPAAAAEPHSLRYNLMVLSQD--GSVQSGFLAEGHLDGQPFLRYDRQ--KRRAKPQGQWAENVLGAKTWDTETEDLTENGQDLRRTLTHIKDQKG----------------GLHSLQEIRVCEIHEDS----STRGSRHFYYDGELFLSQNLETQESTVPQSSRAQTLAMNVTNFWKEDAMKTKTHYRAMQADCLQKLQRYLKSG-VAIRRTVPPMVNVTCSEVSE--GNITVTCRASSFYPRNITLTWRQDGVSLSHNTQQWGDVLPDGNGTYQTWVATRIRQGEEQRFTCYMEHSGNHGTHPVPSGKALVLQSQRTDFPYVSAAMPCFVIIIILCVPCCKKKTSAAEGPELVSLQVLDQHPVGTGDHRDAAQLGFQPLMSATGSTGSTEGT------------------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :.. : * . . : . . : : * : .* . : : * * :** : : . : *:* : . : * : * ", "identical_positions": 11, "similar_positions": 28, "identity": "2.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130212-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XHZ6-1", "uniprot_id": "KLHL7_RAT", "id": "Q5XHZ6-1", "name": "Kelch-like protein 7", "aln": "MATSGVEKSS--KKKTEKKLAAREEAKLLAGFMGVMNNMRKQRTLCDVILMVQERKIPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKSTADDFIHQHFTEVYKTDEFLQLDVKRVTHLLSQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELAGGTRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLSSCEVYDPATETWTELCSMIEPRKNHGLVFVKDKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWRGVTVKCAAVGSVIYVLAGFQGVGRLGHILEYNTETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BUL5-1", "uniprot_id": "KLHL7_MOUSE", "id": "Q8BUL5-1", "name": "Kelch-like protein 7", "aln": "MATSGVEKSS--KKKTEKKLAAREEAKLLAGFMGVMNNMRKQRTLCDVILTVQERKIPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKRVTHLLSQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELAGGTRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLSSCEVYDPATETWTELCSMIEPRKNHGLVFVKDKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWRGVTVKCAAVGSVIYVLAGFQGVGRLGHILEYNTETDKWIANSKVRAFPVTSCLICVVDTCGANEETLET------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IXQ5-1", "uniprot_id": "KLHL7_HUMAN", "id": "Q8IXQ5-1", "name": "Kelch-like protein 7", "aln": "MAASGVEKSS--KKKTEKKLAAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQERKIPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSKTVQAEPLIQDNPECLKMVISGMRYHLLSPEDREELVDGTRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWTDIRCPFEKRRDAACVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPTPRDSLAACAAEGKIYTSGGSEVGNSALYLFECYDTRTESWHTKPSMLTQRCSHGMVEANGLIYVCGGSLGNNVSGRVLNSCEVYDPATETWTELCPMIEARKNHGLVFVKDKIFAVGGQNGLGGLDNVEYYDIKLNEWKMVSPMPWKGVTVKCAAVGSIVYVLAGFQGVGRLGHILEYNTETDKWVANSKVRAFPVTSCLICVVDTCGANEETLET------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PBW9-1", "uniprot_id": "A0A8M1PBW9_DANRE", "id": "A0A8M1PBW9-1", "name": "", "aln": "MASTTCEKALGPKKKSEKKIASKEEYRLLSNIMGVMNNLRKQGILCDVILVVEGKHILAHRVVLSAASHFFSLMFTSSMMEASNHEVELGGAEPEIIELLVEFIYTARISVNSNNVQSLLNAANQYQIDPVKKMCVDFLKEQVDATNCLGISALAECLNCPELKVAADDFIHQHFTNVYKMDEFLQLDVKQVTHLLQQDTLTVRAEDQIYDAAVRWLKYDVLNRQHYIVDILGKVRFPLVSKNFLSKTVQAEPLIQDNPECLKMVICGMRYHLLSPEDREELGESSRPRRKKHDYRIALFGGSQPQSCRYFNPKDYSWSDIRCPFEKRRDAASVFWDNVVYILGGSQLFPIKRMDCYNVVKDSWYSKLGPPNPRDSLAACASKGKIYTSGGSEVGSSALNLFECYDTRTEAWQTKPNMLMPRCSHGSVEANGLIYVCGGSLGNNVSGRVLNDCEVYDPNTEEWRGLCGMREARKNHGLVVVNSRIYAVGGQNTLGGLDSVEYYEIGSNEWKMASPMPWRGVTVKCAAVGSVIYVLAGFQGVGRLGHIMEYYTDTDKWVVSSKVRAFPVTSCLICLVDTCGANEEDMSFTPSSSSSSSSASLADGRM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:: **: ***:***:*::** :**:.:******:*** ****** *: ::* ******:******.****:.*:*:...**** .***:*** **** ****************:*******:****************:******.*****:***** :**********:*** *********:*****.***********:*********** *** ::****.******:**************************.*************** .:********************************:*************.**************************************.*********::************.*** **********:*:***.** ***** ***********************..****** ** * ** * *.*******.*:.:*:****** *****.****:* *****.*****:***********::***************:** *:****:..**************:********* :. ", "identical_positions": 477, "similar_positions": 74, "identity": "78.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130214-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LPQ2-1", "uniprot_id": "ASCC3_RAT", "id": "F1LPQ2-1", "name": "Activating signal cointegrator 1 complex subunit 3", "aln": "-MALPRLTGALRSFSNVTKQDNYNEEVADLKLKRSKLHEQALDFGLSWKKIVKFLNEKLEKNKMQTINEDLKDILQAAKQIVGTDNGNEAIESGAAFLFMTFHMTDSVGYTETKAIRQMFGPFPSSSATSACNATSRIISHFSQDDLTALVQATENQCNDRVVFGRNLAFSFDMHDLDHFDELPVNGEAQKTISLDYKKFLNEQFQEPYTPELKPVEKSNGSLLWCEVEKYLNATLKEMTEAPRVEDLCCTLYDMLASAKSGDELQDELFELLGPGGLDLIEKLLQNRITIVDRFLNSSSDHK--FQVLQDNCKKILG---ENAKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAG-EDGEVSGEGLLPFDPKELRLQREHALLNARS-APILGRQRDTEVEK--------IRYPHVYDSQAAARETSAFIAGAKMILPEGIQRENTKLYEEVRIPYSEPMPVG--FEEKPVYIQDLDEVGQLAFKGMKRLNRIQSIVFDTAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFHQG-----VLKKNEFKIVYVAPMKALAAEMTNYFSKRLEPLGIVVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVKLLILDEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFYFDGRFRPVPLGQTFLGIK-SANKMQQLNNMDEVCYESVLKQVKAGHQVMVFVHARNATVRTAMSLIERAKNSGQISCFLPTQGPEYGHALKQVQKSRNKQVRELFSDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQIFGRAGRPQFDKF-GEGIIITTHDKLSHYLSLLTQQNPIESQFLESLADNLNAEIALGTVTNVEEAVKWMSYTYLYVRMRANPLAYGISHKAYQMDPTLRKHREQLLIEVGQKLDKARMIRFEERTGYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVREEEIEELDALLNNFCELSAPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAARIVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSVLPPHILTRLEEKNLTVDKLKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVTMEASIQPITRTVLRVSLNIYPDFSWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVINKEAQLLVFTIPIFEPLPSQYYIRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPVTALGCKAYEALYNFSHFNPVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKIRIEEK-LGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRSYVQQVNILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRPVPLEVHIQGFPG-QHYCPRMASMNKPAFQESHTHCPDRPCLLLP-ERMLSSMTKLELIAFLATEEDPKQWLNMD-EQEMENIIATVRDSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQDALDYITWTYFFRRLIMNPSYYNLG-DVSQDAINKFLSHLIGQSLVELELSHCIEVGEDNRSIEPLTCGRIASYYYLKHKTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHTNNELAKCLPIELNPHSFDS-------PHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQALRVCQAMLDVAASQGWLVTTLNITHLIQMVIQGRWLKDSSLLTIPNIEQHHLHLFRKWKPPVKGPHAKCRTSIECLPELIHACEGKEHVFSSMVEKELQPAKTKQAWNFLSHLPVINVGISVKGSWDDSVEGHNELSISTLTADKRDENTWIKLHADQQYVLQVSLQRVHFEFHK--VKHESHAVTPRFPKLKDEGWFLILGEVDKRELVAVKRVG--FVRTHHEASISFFTPEAPGRYIFTLYLMSDCYLGLDQQYDIFLNVTKADISTQINTEVPDVST-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PZJ8-1", "uniprot_id": "ASCC3_MOUSE", "id": "E9PZJ8-1", "name": "Activating signal cointegrator 1 complex subunit 3", "aln": "-MALPRLTGALRSFSNVTKQDNYNEEVADLKLKRSKLHEQVLDFGLTWKKIVKFLNEKLEKNKMQNINEDLKDILQAAKQIVGTDNGREAIESGAAFLFMTFHMTDSVGYMETKAIRQTFGPFPSSSATSACNATNRIISHFSQDDLTAFVQMAENPCNDRVVFGKNLAFSFDMYDLDHFDELPINGESQKTISLDYKKFLNEQFQEPYTPELKPVEKTNGSLLWCEVEKYLNATLKEMTEAARVEDLCCTLYDMLASAKSGDELQDELFELLGPEGLDLIEKLLQNRITIVDRFLNSSSDHK--FQVLQDSCKKILG---ENSKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAG-EDGEVSGEGVLPFDPKELRIQREHALLNARN-APILGRQRDVEFEK--------IRYPHVYDSQAQARETSAFIAGAKMILPEGIQRENTKLYEEVRIPYGEPMPVG--FEEKPVYIKDLDEVGQLAFKGMKRLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTILHEIRQHFHQG-----VIKKNEFKIVYVAPMKALAAEMTNYFSKRLEPLGIVVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVKLLILDEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFYFDGRFRPVPLGQTFLGIK-STNKMQQLNNMDEVCYESVLKQVKAGHQVMVFVHARNATVRTAMSLIERAKNSGQISCFLPTEGPEYGHALKQVQKSRNKQVRELFSDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVVIKGTQIYAAKRGSFVDLGILDVMQIFGRAGRPQFDKF-GEGIIITTHDKLSHYLSLLTQQNPIESQFLESLADNLNAEIALGTVTNVEEAVRWMSYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLLIEVGQKLDKAKMIRFEERTGYFSSTDLGRTASHFYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVREEEIEELDALLNNFCELSAPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAARIVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSVLPPHILTRLEEKNLTVDKLKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVTMEASIQPITRTVLRVSLNIHPDFSWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVINKEAQLLVFTIPIFEPLPSQYYIRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYNFSHFNPVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKIRIEEK-LGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRSYVQQVNILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRPVPLEVHIQGFPG-QHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQTRLTALELIAFLATEEDPKQWLNMD-EQEMDNIIGTVRDSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQDAMDYITWTYFFRRLIMNPSYYSLG-DVSQDSINKFLSHLIGQSLVELELSHCIEVGEDNRTIEPLTCGRIASYYYLKHKTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHTNNELAKCLPIELNPHSFDS-------PHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQALRVCQAMLDVAASQGWLVTVLNITHLIQMVIQGRWLKDSSLLTIPNIEQHHLHLFRKWKPPVKSSHAKCRTSIECLPELIHACEGKDHVFSSMVEKELQPAKTKQAWNFLSRLPVINVGISVKGSWDDLVEGHNELSISTLTADKRDENKWIKLHADQEYVLQVSLQRVHFGLPK--GKHENHAVTPRFPKLKDEGWFLILGEVDKRELMAVKRVG--FVRTHHDASISFFTPETPGRYIFTLYLMSDCYLGLDQQYDIYLNVIKANISTKDSDVFTDLSV-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N3C0-1", "uniprot_id": "ASCC3_HUMAN", "id": "Q8N3C0-1", "name": "Activating signal cointegrator 1 complex subunit 3", "aln": "-MALPRLTGALRSFSNVTKQDNYNEEVADLKIKRSKLHEQVLDLGLTWKKIIKFLNEKLEKSKMQSINEDLKDILHAAKQIVGTDNGREAIESGAAFLFMTFHLKDSVGHKETKAIKQMFGPFPSSSATAACNATNRIISHFSQDDLTALVQMTEKEHGDRVFFGKNLAFSFDMHDLDHFDELPINGETQKTISLDYKKFLNEHLQEACTPELKPVEKTNGSFLWCEVEKYLNSTLKEMTEVPRVEDLCCTLYDMLASIKSGDELQDELFELLGPEGLELIEKLLQNRITIVDRFLNSSNDHR--FQALQDNCKKILG---ENAKPNYGCQVTIQSEQEKQLMKQYRREEKRIARREKKAG-EDLEVS-EGLMCFDPKELRIQREQALLNARS-VPILSRQRDADVEK--------IHYPHVYDSQAEAMKTSAFIAGAKMILPEGIQRENNKLYEEVRIPYSEPMPLS--FEEKPVYIQDLDEIGQLAFKGMKRLNRIQSIVFETAYNTNENMLICAPTGAGKTNIAMLTVLHEIRQHFQQG-----VIKKNEFKIVYVAPMKALAAEMTDYFSRRLEPLGIIVKELTGDMQLSKSEILRTQMLVTTPEKWDVVTRKSVGDVALSQIVRLLILDEVHLLHEDRGPVLESIVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPYIGLFFFDGRFRPVPLGQTFLGIK-CANKMQQLNNMDEVCYENVLKQVKAGHQVMVFVHARNATVRTAMSLIERAKNCGHIPFFFPTQGHDYVLAEKQVQRSRNKQVRELFPDGFSIHHAGMLRQDRNLVENLFSNGHIKVLVCTATLAWGVNLPAHAVIIKGTQIYAAKRGSFVDLGILDVMQIFGRAGRPQFDKF-GEGIIITTHDKLSHYLTLLTQRNPIESQFLESLADNLNAEIALGTVTNVEEAVKWISYTYLYVRMRANPLAYGISHKAYQIDPTLRKHREQLVIEVGRKLDKAQMIRFEERTGYFSSTDLGRTASHYYIKYNTIETFNELFDAHKTEGDIFAIVSKAEEFDQIKVREEEIEELDTLLSNFCELSTPGGVENSYGKINILLQTYISRGEMDSFSLISDSAYVAQNAARIVRALFEIALRKRWPTMTYRLLNLSKVIDKRLWGWASPLRQFSILPPHILTRLEEKKLTVDKLKDMRKDEIGHILHHVNIGLKVKQCVHQIPSVMMEASIQPITRTVLRVTLSIYADFTWNDQVHGTVGEPWWIWVEDPTNDHIYHSEYFLALKKQVISKEAQLLVFTIPIFEPLPSQYYIRAVSDRWLGAEAVCIINFQHLILPERHPPHTELLDLQPLPITALGCKAYEALYNFSHFNPVQTQIFHTLYHTDCNVLLGAPTGSGKTVAAELAIFRVFNKYPTSKAVYIAPLKALVRERMDDWKVRIEEK-LGKKVIELTGDVTPDMKSIAKADLIVTTPEKWDGVSRSWQNRNYVQQVTILIIDEIHLLGEERGPVLEVIVSRTNFISSHTEKPVRIVGLSTALANARDLADWLNIKQMGLFNFRPSVRPVPLEVHIQGFPG-QHYCPRMASMNKPAFQAIRSHSPAKPVLIFVSSRRQTRLTALELIAFLATEEDPKQWLNMD-EREMENIIATVRDSNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKVQVLIATSTLAWGVNFPAHLVIIKGTEYYDGKTRRYVDFPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLGVLSDHLNAEIAGGTITSKQDALDYITWTYFFRRLIMNPSYYNLG-DVSHDSVNKFLSHLIEKSLIELELSYCIEIGEDNRSIEPLTYGRIASYYYLKHQTVKMFKDRLKPECSTEELLSILSDAEEYTDLPVRHNEDHMNSELAKCLPIESNPHSFDS-------PHTKAHLLLQAHLSRAMLPCPDYDTDTKTVLDQALRVCQAMLDVAANQGWLVTVLNITNLIQMVIQGRWLKDSSLLTLPNIENHHLHLFKKWKPIMKGPHARGRTSIESLPELIHACGGKDHVFSSMVESELHAAKTKQAWNFLSHLPVINVGISVKGSWDDLVEGHNELSVSTLTADKRDDNKWIKLHADQEYVLQVSLQRVHFGFHK--GKPESCAVTPRFPKSKDEGWFLILGEVDKRELIALKRVG--YIRNHHVASLSFYTPEIPGRYIYTLYFMSDCYLGLDQQYDIYLNVTQASLSAQVNTKVSDSLTDLALK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F8F4-1", "uniprot_id": "ASCC3_DANRE", "id": "E7F8F4-1", "name": "Activating signal cointegrator 1 complex subunit 3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVDVNDVIHANEKAQIDFAQMLLPEGIRRDNNKMYEEVEIPPNEPMPIG--FEEKAVFVSELDEIGQLVFKGMKRLNRIQSIVFETAYNTNENLLICAPTGAGKTNIAMLTILHEIRQHLQPGG----VIRKDQFKIVYVAPMKALAAEMTNYFSKRLEPLGIAVKELTGDMQLTKGEILRTQMLVTTPEKWDVVTRKSVGDVALSQVVRLLILDEVHLLHEDRGPVLESLVARTLRQVESTQSMIRILGLSATLPNYLDVATFLHVNPFIGLFYFDSRFRPVPLGQSFVGIK-TTNKVQQLHDMEEVCYEKVLKQIKAGHQVMVFVHARNSTVRTAMSLIEMAKNRGELSFFQVDQGADYGQCEKQIQRSRNKQMREMFPDGFGIHHAGMLRQDRSLMESMFSRGYLKVLVCTATLAWGVNLPAHAVIIKGTNIYDAKRGTLVDLGILDVMQIFGRAGRPQFDKY-GEGTIITTHDKLSHYLTLLTQQNPIESQFQQSLADNLNAEIALGTVTNVDEAVRWLSYTYLYVRMRANPLAYGINHKAYQMDPQLELYRKELVVESGRKLDKARMIRFDERTGYFASTDLGRTASHFYIKYNTIESFNELFNAQNTEADVLSIVSKAEEFEQIKVRVQ-------------EEDADG-----KSSVQILCGSHHT------------------NAARIMRALFEMALRKRWPAMTYRLLNLCKVMDKRLWGWAHPLRQFNTLPASALARMEDKNLTIDKLRDMGKDEIGHMLHHVNIGLKVKQCVHQIPAILLESSIQPITRTVLRVRLSITPDFRWNDQVHGSVGEPWWLWVEDPINDHIYHSEYFLLQKKQVVSGEPQQVVFTIPIFEPMPSQYYIRAVSDRWLGSEAVCIINFQHLILPERHPPHTELLDLQPLPITALGNREYESLYKFTHYNPIQTQIFHTLYHTDTNVLLGAPTGSGKTIAAEMAIFRVFNMYPTSKVVYIAPLKALVRERIEDWKIRIEEK-LGRKVVELTGDNTPDMRAIAQADLIVTTPEKWDGVSRSWQNRSYVQKVAILIIDEIHLLGEDRGPVLEVIVSRTNFISSHTSKTVRVVGLSTALANARDLADWLGIGQVGLFNFRPSVRPVPLEVHIQGFPG-QHYCPRMATMNKPVFQAIRTHSPAKPVLIFVSSRRQTRLTALDLIAFLATEDDPKQWLHQD-EREMTDIIATIRESNLKLTLAFGIGMHHAGLHERDRKTVEELFVNCKIQVLIATSTLAWGVNFPAHLVIVKGTEYYDGKTRRYVDYPITDVLQMMGRAGRPQFDDQGKAVILVHDIKKDFYKKFLYEPFPVESSLLSVLSDHLNAEIAAGTVTSKQDAMDYITWTYFFRRLVMNPSYYNLD-DISHETINKYLSNLVERSLRDLECSYCMEIQQDEQTIEPLTYGRISSYYYLKHQTIRMFKERLKPELPVHELLAILS------------------------------------------------------------LPCSDYGTDTKTVLDNAIRICQAMLDVVANEGWLVSALSLCNLVQMIIQARWLHDSSLLTLPHIQKQELYVFRRWSSRGVRAGCGHQGPIEGLPELIAACDGKEDIFTSMVKEVLQPNQISQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VF56-1", "uniprot_id": "Q9VF56_DROME", "id": "Q9VF56-1", "name": "Activating signal cointegrator 1 complex subunit 3", "aln": "MWEPPRLSASLRAKTELEARSRRLNVLR--QARTTSAASTTTNSQNKEEQTIARLLAQMPTEKQPAAKVQLQKLRNLVQECMGYEEQPQVVEHAALFLFWLLLDQRVLLVATTQRLHGMFGQTFDRKKTQIHDCVQAIGDLLEDHERSALKRWRQTHHKVPGVGPLWGAHIHVKCTPSEWMDISLLTDLAPDALLKNRTVN--KFSMKHTTKAAPVASTSSEAAKLSPELQT---LLEISAKLDDEHLIIRVGDILGSQRSSEVLQNELMEILGFDYFELVEKLLMERDKIARQLDQFATRSRRVMEVKQKRMEAAASGGAAERRPTVASAVVVQSAQEKQLSKMQRREEKKLQRIMRSIKDEEAEDDPNCAVAVSVQQLRMQHQRKLLEAAQREPLLLSTKAAKAEYKQSSYNQPIHYPYVFDSQLLAKQHAGFIGGSRITLPDNAQRIDNKQWEEVKIPASEPPPLS--VGNKRVQIEELDDVGRLAFANCKELNRIQSVVFPVAYHSNENMLVCAPTGAGKTNVAMLSIVHTIRCHLEQG-----VINRDEFKIVYIAPMKALAAEMVDNFSKRLKSLQIAVRELTGDIQLTKAEMAATQILVTTPEKWDVVTRKGSGDVALISLVELLIIDEVHLLHGERGPVVEALVARTLRLVESSQSMIRIVGLSATLPNYIDVAHFLRVNPMKGLFYFDSRFRPVPLDTNFVGIK-SVKQLQQIADMDQCCYQKCVEMVQEGHQIMVFVHARNATVRTANVIRELAQQNNTSALFLPKDSAAHGLATRSIQRSRNKQLVELFSCGLAMHHAGMLRADRQMVEKYFVEGHISVLVCTATLAWGVNLPAHAVIIRGTDIYDAKHGSFVDLGILDVLQIFGRAGRPQFDKS-GVGTIITSYDKLNHYLSLLTNQFPIESNFVNCLADNLNAEIGLGTITNVDEAIEWLSYTYLFVRMRINPHVYGIEYSELEKDPTLEARRRALIMSAAMSLDKARMMRFNQRTMDMNITDLGRTASYFYIKYDTVETFNELMKPFMTQAEILAMISQAQEFQQLKVRDDEMEELDELKNAYCKIKPYGGSENVHGKVNILIQTYLSNGYVKSFSLSSDMSYITTNIGRISRALFSIVLRQNNAVLSGNMLQLCKMFERRQWDFDCHLKQFPTINAETIDKLERRGLSVYRLRDMEHRELKEWLRSNTYADLVIRSAHELPLLEVEASLQPITRTVLRIKVDIWPSFTWNDRVHGKTCQSFWLWIEDPESNYIYHSELFQVTRKLVMSGQSQQLVMTIPLKEPLPPQYYIRVSSDNWLGSTTCIPLSFQHLVLPEHHPPLTELLPLRPLPVSCLKNVVYESLYKFTHFNPIQTQIFHCLYHTDNNVLLGAPTGSGKTIVAEIAIFRALNQNPKCKVVYIAPLKALVKERIADWEQRFQRSSLGLKVVELTGDVTPDIQAIRESQLIVTTPEKWDGISRSWQTREYVQHVSLIVIDEIHLLGEDRGPVIEVIVSRTNFISSHTGRAIRIVGLSTALANAQDLANWLGINKMGLYNFKPSVRPVPLQVHINGFPG-KHYCPRMATMNRPTFQAIRTYSPCEPTIVFVSSRRQTRLTALDLITFVAGESNPKQFLHIP-EDEIELILQNIREQNLKFCLAFGIGLHHAGLQEQDRKCVEELFLNRKIQILVATATLAWGVNLPAHLVVIKGTEYFDGKVKKYVDMPITDVLQMMGRAGRPQFDNEGVAVVLVHDEKKNFYKKFLYDPFPVESSLLGVLPEHINAEIVAGTVQSKQAALDYLTWTYFFRRLLRNPSYYQLQ-DIEPENVNNFMSNLVERVVYELSAAACLVERDG--CLIPTFLGRISSYYYLSYRTMKHFLEDLQPGMNTKKVLLAIADSYEFDQLPVRHNEDKHNEEMAEVSRFRPPSSSWDS-------SYTKTFLLLQAHFARQSLPNSDYLTDTKSALDNATRVMQAMVDYTAERGWLSTTLVVQQLMQSVIQARWFDGSEFLTLPGVNEDNLDAFLNIP--------HDDYDYLTLPVLKELCKQEYEVLAKPLRDAFEEHEIEKMYKVIQDLPEIAIQIFVEG-----RHMENEYAKRPLSLSDDTRGEWMSLHANEDYVLIVNLQRLNVSGQRRGGGQSYTVHCPKYPKPKNEAWFLTLGSQANDELLAMKRVS--IRGQRCTNRISFQATPRLGRLQLTLYLMSDCLMGFDQQYDLQFEIIDAKEV-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53327-1", "uniprot_id": "ASCC3_YEAST", "id": "P53327-1", "name": "RQC trigger complex helicase SLH1", "aln": "-----------------------------------MSTEYSADSSKSFMIAMQSMIDTSQTFNLDRSKISLPDFDDELKKVQKDE----------------------------------------------------------QNQRTELTVLSQ--------------------DRNDWDDI------------------FEEFKDISFAQLQSIIDSYKTKNAVAVYKKIGKLINEAETTLSSNVLLETVLQMVYKHQK-QELEKELLDFLGTGNIDLVSLLLQHRRMIVATPIETT------ILLIKN---------AVNSTPEFLTQQDIRNQVLKSAEDAKNRKLNPATKI------------------------------------------------------------IKYPHVFRKYEAGSTTAMAFAGQKFTLPVGTTRMSYNTHEEIIIPAADQASNKNYLYTKLLKISDLDHFCKTVFP-YETLNQIQSLVYPVAYKTNENMLICAPTGAGKTDIALLTIINTIKQFSVVNGENEIDIQYDDFKVIYVAPLKALAAEIVDKFSKKLAPFNIQVRELTGDMQLTKAEILATQVIVTTPEKWDVVTRKANGDNDLVSKVKLLIIDEVHLLHEDRGSVIETLVARTLRQVESSQSMIRIIGLSATLPNFMDVADFLGVNRQIGMFYFDQSFRPKPLEQQLLGCRGKAGSRQSKENIDKVAYDKLSEMIQRGYQVMVFVHSRKETVKSARNFIKLAESNHEVDLFAP-DPIEKDKYSRSLVKNRDKDMKEIFQFGFGIHHAGMARSDRNLTEKMFKDGAIKVLCCTATLAWGVNLPADCVIIKGTQVYDSKKGGFIDLGISDVIQIFGRGGRPGFGSANGTGILCTSNDRLDHYVSLITQQHPIESRFGSKLVDNLNAEISLGSVTNVDEAIEWLGYTYMFVRMRKNPFTYGIDWEEIANDPQLYERRRKMIVVAARRLHALQMIVFDEVSMHFIAKDLGRVSSDFYLLNESVEIFNQMCDPRATEADVLSMISMSSEFDGIKFREEESKELKRLSDESVECQIGSQLDTPQGKANVLLQAYISQTRIFDSALSSDSNYVAQNSVRICRALFLIGVNRRWGKFSNVMLNICKSIEKRLWAFDHPLCQFD-LPENIIRRIRDTKPSMEHLLELEADELGELVHNKKAGSRLYKILSRFPKINIEAEIFPITTNVMRIHIALGPDFVWDSRIHG-DAQFFWVFVEESDKSQILHFEKFILNRRQLNN--QHEMDFMIPLSDPLPPQVVVKVVSDTWIGCESTHAISFQHLIRPFNETLQTKLLKLRPLPTSALQNPLIESIYPFKYFNPMQTMTFYTLYNTNENAFVGSPTGSGKTIVAELAIWHAFKTFPGKKIVYIAPMKALVRERVDDWRKKITPV-TGDKVVELTGDSLPDPKDVHDATIVITTPEKFDGISRNWQTRKFVQDVSLIIMDEIHLLASDRGPILEMIVSRMNYISSQTKQPVRLLGMSTAVSNAYDMAGWLGVKDHGLYNFPSSVRPVPLKMYIDGFPDNLAFCPLMKTMNKPVFMAIKQHSPDKPALIFVASRRQTRLTALDLIHLCGMEDNPRRFLNIDDEEELQYYLSQVTDDTLKLSLQFGIGLHHAGLVQKDRSISHQLFQKNKIQILIATSTLAWGVNLPAHLVIIKGTQFFDAKIEGYRDMDLTDILQMMGRAGRPAYDTTGTAIVYTKESKKMFYKHFLNVGFPVESSLHKVLDDHLGAEITSGSITNKQEALDFLSWTFLFRRAHHNPTYYGIEDDTSTAGVSEHLSSLIDSTLENLRESQCVLLHGDDIVATPFLS--ISSYYYISHLTIRQLLKQIHDHATFQEVLRWLSLAVEYNELPVRGGEIIMNEEMSQQSRYSVESTFTDEFELPMWDPHVKTFLLLQAHLSRVDLPIADYIQDTVSVLDQSLRILQAYIDVASELGYFHTVLTMIKMMQCIKQGYWYEDDPVSVLPGLQLRRIKDY--------------TFSEQGFIEMTPQQKKK----KLLTLEEIGRFGYKKLLNVFDQLTFG------------MTESEDTKKRFVSVCQRLPVLEGMKFEEQENNEVLTFYSKHLSSKHN----NGFEVYCDKFPKIQKELWFLIG--HKGDELLMIKRCQPKQMNKEVIIHCDLFIPEEIRGEELQFSLINDALG---LRYDMVHKLIS---------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : :: ** . * . : **: ** : . . * : :.:**.. : .* : **:***:*: .**::***:*:*********::*:*:::: *: . . :. ::**::*:**:******:.: **::* .: * *:*****:**:*.*: **::*************. ** * . *.***:******* :**.*:*::****** ***:******:********::*** ** ** *:*:** *** ** ::* : . . *. :::: .*:. : :: *:*:*****:*: **::* : : *:. * : :.: :.*:*:: *:* *:.:***** * **.: *. * * :.** *************..*:*:**::* :*:* ::**** **:*****.*** *.. * * : *: *:*.**::*:*:: ****.* . *.*******.**::***:**:.*:.***::**** ** .***. . ** * *. ::: . *. :*: *:: : : .****.:* :*: :::* **:: .. *:.::::::* :.**: :*.* : : . . .. ::* :: : * ** **** : :.:. :: :*::.* :::* * : * ** : : ::. :: :* :: *: . :: . . : : .:* : :*:.: *** .*:*: : : ..* *:.::** : :*:::*:. .. * * * * :: : . : : : **: :*:*.* ::. ** *:*. : :.****: * ... *:** *:*** :.* *::* *.::**:** *: **:*: *.::*:*******:.**:**::.:: * * *****:****:**: **. :: * **:***** ** : : .: :::*****:**:**.**.*.:**.* ::::******..:***::*:**** *:***:* :.:*::*:***::** *:*.**.: . **:** .*******:::*:***. :** * :**:*.* : :.* .* ::: .* : :* *:** : . *.:*:::*: * *: : : :..**: * ****:***** ::**. .:** : *:*:*:**:*******:*****::***:::*.* . * * :**:********** :* * *:: .:: ** ***:** ******* ** :*:.***..*:: .** *:*:::**::*** **:** : * . :.:.:* *: : :* : *: . * *:****:.: *:: : . :: .::* :: ** .** ** :.**:: *: ** :* .:. *:: :.* : :::* : *. * ... . .:* :: .: : : : : . : .: ", "identical_positions": 570, "similar_positions": 506, "identity": "25.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130215-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GKB1-1", "uniprot_id": "A0A8I6GKB1_RAT", "id": "A0A8I6GKB1-1", "name": "Molybdenum cofactor biosynthesis protein 1", "aln": "------------MAARPASRMLRQLLRSNVRSCS--------SGAPMTQPRPGEPSRPTREGLSMRLQFLQEHAAPFSAFLTDSFGRQHSYLRISLTEKCNLRCRYCMPEEGVSLTPKADLLTTEEILTLARLFVKEGVDKIRLTGGEPLIRPDVVDIVARLHQLEGLRTIGVTTNGINLARLLPSLQQAGLSAVNVSLDTLVPAKFEFIVRRKGFHKVMEGIHKAIELGYKPVKVNCVVMRGLNEDELLDFVALTEGLPLDVRFIEYMPFDGNKWNFKKMVSYKEMLDAIRQRWPGLEKLPEEDSSTAKAFKIPGFQGQISFITSMSEHFCGTCNRLRITADGNLKVCLFGNSEVSLRDHLR-AGASEEELLRIIGVAVGRKKRQHAGMFNIAQMKNRPMILIG-----VLLMLQD-------------------SPPASWSTLSWDPLHVR----------------------------NPGAKQCLSDQMATLWKRHSVPMALPLSQQCLGSGSPQRHYSSYPDPD---------THPKCLSTGS---------------------RAPDVPSGPGPTSDQLTHVDSAGRATMVDVGGKPETERVAVASAMVLLGPKAFKLVQQNQLKKGDALVVAQLAGVQAAKLTSQLIPLCHHVALSHVQVHLELDSTRHAVLIQVSCRARGPTGVEMEALTSAAMAALTVYDMCKAVSRDIVVTEVKLISKTGGQRGDFHRT-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5RKZ7-1", "uniprot_id": "MOCS1_MOUSE", "id": "Q5RKZ7-1", "name": "Molybdenum cofactor biosynthesis protein 1", "aln": "------------MAARPAFGIVRQLLRSNARGCS--------SGAPVTQPRPGEPSRPTREGLSLRLQFLQEHAAPFSAFLTDSFGRQHSYLRISLTEKCNLRCQYCMPEEGVPLTPKADLLTTEEILTLARLFVKEGVDKIRLTGGEPLIRPDVVDIVARLHGLEGLRTIGLTTNGINLARLLPRLQQAGLNAVNISLDTLVPAKFEFIVRRKGFHKVMEGIHKAIELGYKPVKVNCVVMRGLNEDELLDFVALTEGLPLDVRFIEYMPFDGNKWNFKKMVSYKEMLDTIRQRWPGLEKLPEEDSSTAKAFKIPGFQGQISFITSMSEHFCGTCNRLRITADGNLKVCLFGNSEVSLRDHLR-AGASEEELLRIIGAAVGRKKRQHAGMFNIAQMKNRPMILIG-----VLLMLQD-------------------SPPARWSNFSWDPLRVR----------------------------NPSARQCLSDQMASLWKRHCIPKALPLSQQCLGSGSPQRHYSSYPDPD---------THSKCLSTGS---------------------QAPDAPSGPGPTSNQLTHVDSAGRASMVDVGGKPETERVAVASAMVLLGPVAFKLVQQNQLKKGDALVVAQLAGVQAAKLTSQLIPLCHHVALSHVQVHLELDSTRHAVLIQASCRARGPTGVEMEALTSAAMAALTVYDMCKAVSRDIVVTEVKLISKTGGQRGDFHRA-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZB8-1", "uniprot_id": "MOCS1_HUMAN", "id": "Q9NZB8-1", "name": "Molybdenum cofactor biosynthesis protein 1", "aln": "------------MAARPLSRMLRRLLRSSARSCS--------SGAPVTQPCPGESARAASEEVSRRRQFLREHAAPFSAFLTDSFGRQHSYLRISLTEKCNLRCQYCMPEEGVPLTPKANLLTTEEILTLARLFVKEGIDKIRLTGGEPLIRPDVVDIVAQLQRLEGLRTIGVTTNGINLARLLPQLQKAGLSAINISLDTLVPAKFEFIVRRKGFHKVMEGIHKAIELGYNPVKVNCVVMRGLNEDELLDFAALTEGLPLDVRFIEYMPFDGNKWNFKKMVSYKEMLDTVRQQWPELEKVPEEESSTAKAFKIPGFQGQISFITSMSEHFCGTCNRLRITADGNLKVCLFGNSEVSLRDHLR-AGASEQELLRIIGAAVGRKKRQHAGMFSISQMKNRPMILIE-----LFLMFPN-------------------SPPANPSIFSWDPLHVQ----------------------------GLRPRMSFSSQVATLWKGCRVPQTPPLAQQRLGSGSFQRHYTSRADSD---------ANSKCLSPGS---------------------WASAAPSGPQLTSEQLTHVDSEGRAAMVDVGRKPDTERVAVASAVVLLGPVAFKLVQQNQLKKGDALVVAQLAGVQAAKVTSQLIPLCHHVALSHIQVQLELDSTRHAVKIQASCRARGPTGVEMEALTSAAVAALTLYDMCKAVSRDIVLEEIKLISKTGGQRGDFHRA-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AJ79-1", "uniprot_id": "A0A8M3AJ79_DANRE", "id": "A0A8M3AJ79-1", "name": "Molybdenum cofactor biosynthesis protein 1", "aln": "MALNCNTFSRIIFGAHTAAEACVKFCRPVQQACGRYQMCRWYSGVTHEENRLEEVREPVVPGGHRR---VLKDVLPFSQFLTDSFGRRHNYLRISLTEKCNLRCQYCMPQDGVKLTPRSQLLTTHELLTVARLFVQEGVNKIRITGGEPLIRPDILHIIAELRKLEGLKTIAVTTNGMNLAKILPDLKKAGVDLLNISLDTLVPAKFEFITRRKGFHKVMEGIERAIEMGYNPVKVNCVVMRGLNEDELVDFVSLTERKPLDVRFIEYMPFNGNRWNFKMMVSYQEMLDCIKQKWPNLQPLPGEETDTAKAFQIPGFQGQMGFITSMSDHFCGSCNRLRITADGNLKVCLFGNAEVSLRDFLR-SGATEKELLHIIGAAVGRKKKQHAGMLNISKMKNRPMILIGRDCTWLLPMSPFRDNQRQTLPLIHRMDLAAISTTQSLGKCNHRPFHVIGYQDYKSTFVTDALYSFYSLTRFTNRKQNRKALEALCNDRISKSYRVTVSASKQNKSRMLLQHILQKHSRPPVPQSKIFALIPFLSTSRALLKDSALQFARHCHHKTPECGFHLKIRHKDLKSSLDGTSNQLTHTDAQGKASMVNVGAKAVTRRTATACGKVILGPKAFNLVCANQVAKGDALAVAQLAGIMGAKQTSNLIPLCHPLPLDHASVTIELLEEEHAAVIKATCQTTGRTGVEMEALTAVSIASLTLYDMCKSVSHDIIITDVKLLSKTGGQRGDYHL------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQF1-1", "uniprot_id": "MOCS1_DROME", "id": "Q8IQF1-1", "name": "Molybdenum cofactor biosynthesis protein 1", "aln": "----------MRLLARHAIRLLGQENSAGEVASLS-------RGAIRLKATTGYLNLATASVQPLE---PEKQVLRKNSPLTDSFGRHHTYLRISLTERCNLRCDYCMPAEGVPLQPKNKLLTTEEILRLARIFVEQGVRKIRLTGGEPTVRRDIVEIVAQMKALPELEQIGITTNGLVLTRLLLPLQRAGLDNLNISLDTLKRDRFEKITRRKGWERVIAGIDLAVQLGYRP-KVNCVLMRDFNEDEICDFVEFTRNRPVDVRFIEYMPFSGNKWHTERLISYKDTLQIIRQRWPDFKALPNGPNDTSKAYAVPGFKGQVGFITSMTEHFCGTCNRLRLTADGNIKVCLFGNKEFSLRDAMRDESVSEEQLVDLIGAAVQRKKKQHA-------------------------------------------------------------------------------------------------------------------DAAPRLHHHLHPYSYHHAYHT----------------SRLQLQAR--------------------------------NYSQLTHVDGQGKAQMVDVGAKPSTTRLARAEATVQVGEKLTQLIADNQVAKGDVLTVAQIAGIMGAKRTAELIPLCHNISLSSVKVQATLLKTEQSVRLEATVRCSGQTGVEMEALTAVSVAALTVYDMCKAVSHDICITNVRLLSKSGGKR-DFQREEPQNGIVTEVE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: : . .. *. : .. . :.. . *******:*.********:***** **** :** * *: .****.*:* :**:**::*: ***:***** :* *::.*:*.:: * *. *.:****: *:::* *::**:. :*:***** :** *.****:.:*: **. *:::**.* *****:**.:****: **. :*. *:**********.**:*: : ::**:: *: ::*:** :: :* ..*:**: :***:**:.*****::****:*****:*****:******* *.**** :* ..:*::*: :**.** ***:*** : : * :: . .: . .****.*. *:* **:** *. * * * * . * :* :*: **: ***.*.***:**: .** *::****** :.*. .* * . .::. ::.: : * *********:.::*:**:*****:**:** : :::*:**:**:* *:: ", "identical_positions": 245, "similar_positions": 165, "identity": "32.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130221-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVM3-1", "uniprot_id": "RETR1_RAT", "id": "Q5FVM3-1", "name": "Reticulophagy regulator 1", "aln": "MASPAPEEHATQGCPATEEQEPRPGVP----------------GEEAGP-EGAGPQVEEAAGRVAAALTWLLGEPVLWLGWRADELLSWKRPLRSLLAFLGANLLFWFLALTPWRVYHLISVMILGRVIMQIIKDMVLSRARGAQLWRSLSESWEVINSKPDERPRLSHCIAESWMNFSIFLQEMSLFKQQSPGKFCLLVCSVCTFFTILGSYIPGVILSYLLLLFAFLCPLFKCNDIGQKIYSKVKSILLKLDFGIGEYINQKKRERSE-ADKEKSHKDDSEIDFSALCPKISLTVAAKELSVSDTDVSEVSWTDNGTFNLSEGYTPQTDTSDDLDRPS-EEVFSRDLSDFPSLENGAGTNDEDE--LSLGLPTELKTKKQQLNSAHRPSKDRQSAAGLSLPLKSDQALHLMSNLAGDVITAAMTAAIKDQLEGARQALAQAAPTPGDDTDTEEGDDFELLDQAELDQIESELGLTQDQGAEAQQ-SKKSSGFLSNLLGGH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VE91-4", "uniprot_id": "RETR1_MOUSE", "id": "Q8VE91-4", "name": "Reticulophagy regulator 1", "aln": "MASPAPEEHATQGCPATEEQPPRPGVP----------------GEEAGP-EGAGPQVEEAAGRVAAALTWLLGEPVLWLGWRADELLSWKRPLRSLLTFLGANLLFWFLALTPWRVYHLISVMILGRVIMQIIKEMVLSRTRGAQLWRSLTESWEVINSKPDERARLSQCIAESWMNFSMFLQEMSLFKQQSPGKFCLLVCSVCTFFTILGSYIPGVILSYLLLLFAFLCPLFKCNDIGQKIYSKVKSILLKLDFGIGEYINQKKRERSE-ADKEKSHKDDSELDFSALCPKISLTVAAKELSVSDTDVSEVSWTDNGTFNLSEGYTPQTDTSDDLDRPS-EEVFSRDLSDFPSLENGTGTNDEDE--LSLGLPTELKRKKQQLDSAHRPSKERQSAAGLSLPLKSDQALHLMSNLAGDVITAAMTAAIKDQLEGARQALTQVAPTAGEDTDTEEGDDFELLDQAELDQIESELGLTQDQGAEAQQ-SKKSSGFLSNLLGGH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H6L5-1", "uniprot_id": "RETR1_HUMAN", "id": "Q9H6L5-1", "name": "Reticulophagy regulator 1", "aln": "MASPAPPEHAEEGCPAPAAEEQAPPSPPPPQASPAERQQQEEEAQEAGAAEGAGLQVEEAAGRAAAAVTWLLGEPVLWLGCRADELLSWKRPLRSLLGFVAANLLFWFLALTPWRVYHLISVMILGRVIMQIIKDMVLSRTRGAQLWRSLSESWEVINSKPDERPRLSHCIAESWMNFSIFLQEMSLFKQQSPGKFCLLVCSVCTFFTILGSYIPGVILSYLLLLCAFLCPLFKCNDIGQKIYSKIKSVLLKLDFGIGEYINQKKRERSE-ADKEKSHKDDSELDFSALCPKISLTVAAKELSVSDTDVSEVSWTDNGTFNLSEGYTPQTDTSDDLDRPS-EEVFSRDLSDFPSLENGMGTNDEDE--LSLGLPTELKRKKEQLDSGHRPSKETQSAAGLTLPLNSDQTFHLMSNLAGDVITAAVTAAIKDQLEGVQQALSQAAPIPEEDTDTEEGDDFELLDQSELDQIESELGLTQDQEAEAQQ-NKKSSGFLSNLLGGH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q245-1", "uniprot_id": "A0A8M1Q245_DANRE", "id": "A0A8M1Q245-1", "name": "", "aln": "MA------HRRGGCDSLDASEVEPVDQS---------------STTTLNLGGGETMAEKEDEQRQQQPSEVRYPAACYPLCRFSKLINWKRPLWTSAFFATTNIAFWFVSLSPCRVFTLISICLALLVVVQLMRYVTLSRSKGAALWRSMTSSWEIIDSVQEGKSASGSPFTDFWTSLKLFIEETSSFKQQNPGKFCLLVCSMCSFLAILGRYVPGVVISYILVLGIFLWPLVSSHEFG----MWLEPVLQKLDFGVAEFFQKIKENHEKRILQSQTERECIEADLSALFPKMDSTVC-KELSLSDTEVSEVTWTDNGTFNLSEGHTPQTENSDDSDRRSDEEVFTGGLPEFPSLDNGLATNGEDDEDLSIGLPTP-------------PAHPSRVGSTQSEDEPAVQALEAVQRLAGDMITAAVSTAMQERLEAAVAPALLQALAEESDS---EAEDFELLDQSELEQLEGELGLDKANRAELSKPSKPSSGFLSKLLGRH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * ** : . * . : *. .*: : : : .. : * .:*:.***** : * :*: ***::*:* **: ***: : *::*::: :.***::** ****::.***:*:* : :. . ::: * .:.:*::* * ****.**********:*:*::*** *:***::**:*:* ** **...:::* ::.:* *****:.*:::: *.::.: :.::.:: * *:*** **:. **. ****:***:****:************:****:.*** ** * ****: .*.:****:** .**.**: **:**** *:: : .: : : *::. :..****:****:::*::::**.. . * .*: *.:*******:**:*:*.**** : : ** .: .* ******:*** *", "identical_positions": 194, "similar_positions": 148, "identity": "38.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130225-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIQ3-1", "uniprot_id": "CXXC5_RAT", "id": "Q5XIQ3-1", "name": "CXXC-type zinc finger protein 5", "aln": "MSSLGGGSQDAGGSSSSSNTSS--SSGSGQKAGGTDKSATVAAT-APASVADDAPPPERRNKSGIISEPLNKSLRRSRPLSHYSSFGSSGG--AGSMMGGESADKA--AAAAASLLANGHDLAAAMAVDKSNPTSKHKSGAVASLLSKAERATELAAEGQLTLQQFAQSTEMLKRVVQEHLPLMSEAGAGLP-DMEAVAGAEALNGQSDFPYLG------AFPINPGLFIMTPAGVFLAESAL-HMAGLAEYP-MQGELASAISS-GKKKRKRCGMCAPCRRRINCEQCSSCRNRKTGHQICKFRKCEELKKKPSAALEKVMLPSGAAFRWFQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WA4-1", "uniprot_id": "CXXC5_MOUSE", "id": "Q91WA4-1", "name": "CXXC-type zinc finger protein 5", "aln": "MSSLGGGSQDAGGSSSSSNTNS--SSGSGQKAGGTDKSTAVAATTAPTSVADDAPPPERRNKSGIISEPLNKSLRRSRPLSHYSSFGSSGG--GGSMMGVESADKA--AAAAASLLANGHDLAAAMAVDKSNPTSKHKSGAVASLLSKAERATELAAEGQLTLQQFAQSTEMLKRVVQEHLPLMSEAGAGLP-DMEAVAGAEALNGQSDFPYLG------AFPINPGLFIMTPAGVFLAESAL-HMAGLAEYP-MQGELASAISS-GKKKRKRCGMCAPCRRRINCEQCSSCRNRKTGHQICKFRKCEELKKKPSAALEKVMLPSGAAFRWFQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7LFL8-1", "uniprot_id": "CXXC5_HUMAN", "id": "Q7LFL8-1", "name": "CXXC-type zinc finger protein 5", "aln": "MSSLGGGSQDAGGSSSSSTNGSGGSGSSGPKAGAADKSAVVAAA-APASVADDTPPPERRNKSGIISEPLNKSLRRSRPLSHYSSFGSSGGSGGGSMMGGESADKATAAAAAASLLANGHDLAAAMAVDKSNPTSKHKSGAVASLLSKAERATELAAEGQLTLQQFAQSTEMLKRVVQEHLPLMSEAGAGLP-DMEAVAGAEALNGQSDFPYLG------AFPINPGLFIMTPAGVFLAESAL-HMAGLAEYP-MQGELASAISS-GKKKRKRCGMCAPCRRRINCEQCSSCRNRKTGHQICKFRKCEELKKKPSAALEKVMLPTGAAFRWFQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PZH1-1", "uniprot_id": "A0A8M9PZH1_DANRE", "id": "A0A8M9PZH1-1", "name": "CXXC-type zinc finger protein 5", "aln": "MSASGGSMEGSRAVEDEEAQDS----CCGE--------------------EDSSPVVERRNRSGIISAPLSKSLKRSRALSQYIATCSAAA-----VASVANANRL----AQSSMVASG--------VKAHPTASQHRSQVGYAKLDRGALVSGLLDS--PSGLHLAQAAELLRRAG-MLLPVSDPSNVNVGGDMETVSASDSLGSVMDFPLLGNGGVGGSFPYHPGLFIMTPAGVFLADGALSHVTGASEHQQTQSEISSAISANGKKKRKRCGLCPPCRRRINCEQCSSCRNRKTGHQICKFRKCEELKKKPAGGLEKVMLPTGAPFRWFP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: **. :.: . .... .* .* *.:* ****:***** **.***:***.**:* : *:.. : . .*:: * :*::*.* *. .:*:*:* . : *.:. .: * . : ::**::*:*:*. **: . :...: ***:*:.:::*.. *** ** :** :**************:.** *::* :*: *.*::****: *********:*.************************************:..*******:**.**** ", "identical_positions": 143, "similar_positions": 87, "identity": "42.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130306-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZYX6-1", "uniprot_id": "A0A8I5ZYX6_RAT", "id": "A0A8I5ZYX6-1", "name": "", "aln": "-------------------------------MGN--------AAGSAEQPAG----------PTASPPKQPAVPKQPMPAAGELEERFTRVLNCMNLPPDKVQLLSQYDNEKKWELICDQERFQVKNPPAAYIQKLKSYLDTGGVSRKVATDWMSNLGFKRRVQEST--QVLRELETSLRTNHIGWVQEFLNEENRGLDVLLEYLAFAQCSVAYDMESTENVASGTEKNKPLEQ-SVEDLSKAPPSSVP--------------------------KSR-LTIKCPPSPRLTPAHSRKALRNSRIVSQK------DDVHVCIMCLRAIMNYQSGFSLVMNHPACVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHDIILAAFDNFKEVCGEQHRFEKLMEYFRN-EDSNIDFMVACMQFINIVVHSVENMNFRVFLQYEFTHLGLDLYLERLRLTESDKLQVQIQAYLDNVFDVGTLLEETETKNAVLEHMEELQEQVATLTERLRDTENDSMAKIAELEKQ---LSQARKELETLRERFSESTPMVTSRRIPEPEKVPAPTVVRPS----------ALELKVEELEEKGLIRILRGPGDVVSIEILPGAAATPSGDDAPAPRVSTDSPSTAESVPEAASPTPPPPPPPPPPLPNLQSQQEALPSAPPLAPPLPGCAAPPPAPPLPGDLPPPPPPPP--LGTDGPVPPPPPPPP---GGPPDILGGQDPEIGPGVKAKKPIQTKFRMPLLNWVALKPSQITGTVFTELNDEKVLQELDMNDFEEQFKTKSQGPSLDIS-------ALKGKTAHKAPTKATLIEANRAKNLAITLRKGNLGADRICEAIETYDLQTLSLDFLELLTRFLPTDYERSLIARFEKEQRPMEELSEEDRFMLRFSRIQRLPERMNTLTFLGNFPDTAQLLMPQLNAIIAASISIKSSDKLRQILEIVLAFGNYMNSSKRGAAYGFRLQSLDALLEMKSTDRKQTLLHYLVKVIAEKYPQLTGFHSDLHFLDKAGSVSLDSVLGDVRSLQRGLELTQREFVRQDD---CLVLKEFLRANSPTMDKLLADSKTAQEAYESVVEYFGENPKTTSPSMFFSLFSRFTKAYKKAEQEVEQ--WKKEAAA-----DTSGREEPPAPKSPPK-------ARRQQMDLISELKRK----QLKEPLIYESDRDGAIEDIITVLKTVPFT-ARTGKRTSRLLCEAS----LGEEMTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JL26-1", "uniprot_id": "FMNL1_MOUSE", "id": "Q9JL26-1", "name": "Formin-like protein 1", "aln": "-------------------------------MGN--------AAGSAEQPAG----------PTASPPKQPAVPKQPMPAAGELEERFTRVLNCMNLPPDKVQLLSQYDNEKKWELICDQERFQVKNPPAAYIQKLKSYLDTGGVSRKVASDWMSNLGFKRRVQEST--QVLRELETSLRTNHIGWVQEFLNEENRGLDVLLEYLAFAQCSVAYDMESTDSVASGAEKSKPLDQ-SVEDLSKAPPSSVP--------------------------KSR-LTIK------LTPAHSRKALRNSRIVSQK------DDVHVCIMCLRAIMNYQSGFSLVMNHPACVNEIALSLNNKSPRTKALVLELLAAVCLVRGGHDIILAAFDNFKEVCGEQHRFEKLMEYFRH-EDSNIDFMVACMQFINIVVHSVENMNFRVFLQYEFTHLGLDLYLERLRLTESDKLQVQIQAYLDNVFDVGTLLEETETKNAVLEHMEELQEQVATLTERLRDTENDSMAKIAELEKQ---LSQARKELETLRERFSESTPMGTSRRIPEPEKVPVPTVVRPS----------ALELKVEELEEKGLIRILRGPGDVVSIEILPGAAATPSGDDAQAPRVSTDSPSTAESIPEAASP-PPPPPPPPPPLPNLQSQQEAPPSAPPLAPPLPGCAEPPPAPPLPGDLPPPPPPPP--LGTDGPVPPPPPPPP---GGPPDILGGQGPDIGPGVKAKKPIQTKFRMPLLNWVALKPSQITGTVFTELNDEKVLQELDMNDFEEHFKTKSQGPCLDIS-------ALKGKASQKAPTKTILIEANRAKNLAITLRKGNLGADRICQAIETYDLQTLSLDFLELLTRFLPTDYERSLIARFEKEQRPMEELSEEDRFMLRFSRIQRLPERMNTLTFLGNFPDTAQLLMPQLNAIIAASMSIKSSDKLRQILEIVLAFGNYMNSSKRGAAYGFRLQSLDALLEMKSTDRKQTLLHYLVKVIAEKYPQLTGFHSDLHFLDKAGSVSLDSVLGDVRSLQRGLELTQREFVRQDD---CLVLKEFLRANSPTMDKLLADSKTAQEAYESVVEYFGENPKTTSPSMFFSLFSRFTKAYKKAEQEVEQ--WKKEAAA-----DTSGREEPPTPKSPPK-------ARRQQMDLISELKRK----QQKEPLIYESDRDGAIEDIITDLRNQPYIRADTGRRSARRRPPGPPLP-VTTDLAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95466-1", "uniprot_id": "FMNL1_HUMAN", "id": "O95466-1", "name": "Formin-like protein 1", "aln": "-------------------------------MGN--------AAGSAEQPAG----------PAAPPPKQPAPPKQPMPAAGELEERFNRALNCMNLPPDKVQLLSQYDNEKKWELICDQERFQVKNPPAAYIQKLKSYVDTGGVSRKVAADWMSNLGFKRRVQEST--QVLRELETSLRTNHIGWVQEFLNEENRGLDVLLEYLAFAQCSVTYDMESTDNGASNSEKNKPLEQ-SVEDLSKGPPSSVP--------------------------KSRHLTIK------LTPAHSRKALRNSRIVSQK------DDVHVCIMCLRAIMNYQSGFSLVMNHPACVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHDIILAAFDNFKEVCGEQHRFEKLMEYFRN-EDSNIDFMVACMQFINIVVHSVENMNFRVFLQYEFTHLGLDLYLERLRLTESDKLQVQIQAYLDNIFDVGALLEDTETKNAVLEHMEELQEQVALLTERLRDAENESMAKIAELEKQ---LSQARKELETLRERFSESTAMGPSRRPPEPEKAPPAAPTRPS----------ALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPTPGVPTGSPS--PDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSELGPGVKAKKPIQTKFRMPLLNWVALKPSQITGTVFTELNDEKVLQELDMSDFEEQFKTKSQGPSLDLS-------ALKSKAAQKAPSKATLIEANRAKNLAITLRKGNLGAERICQAIEAYDLQALGLDFLELLMRFLPTEYERSLITRFEREQRPMEELSEEDRFMLCFSRIPRLPERMTTLTFLGNFPDTAQLLMPQLNAIIAASMSIKSSDKLRQILEIVLAFGNYMNSSKRGAAYGFRLQSLDALLEMKSTDRKQTLLHYLVKVIAEKYPQLTGFHSDLHFLDKAGSVSLDSVLADVRSLQRGLELTQREFVRQDD---CMVLKEFLRANSPTMDKLLADSKTAQEAFESVVEYFGENPKTTSPGLFFSLFSRFIKAYKKAEQEVEQ--WKKEAAAQEAGADTPGKGEPPAPKSPPK-------ARRPQMDLISELKRR----QQKEPLIYESDRDGAIEDIITVIKTVPFT-ARTGKRTSRLLCEAS----LGEEMPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3APF0-1", "uniprot_id": "A0A8M3APF0_DANRE", "id": "A0A8M3APF0-1", "name": "", "aln": "-------------------------------MGN--------AAGSLEMSPVREIK----RPLSTYGQKPPAAPKLPQPSEEELEERFSIVLNSMNLPPDKVMLLSQYDSEKKWELVCDQERFQVKNPPSAYIQKLKSVLEQGGGRK-----------FKRRVQEST--QVLRELEISLRTNHIGWAEEFLNEENNGLDVLVDYLSFAQRAVIYDMDSSSENGSFEEK-------SVEDLTTSATNSPT--------------------------HNSPRSAR--------PFTTRKALRYSRMLSQN------NHLHLCIMCLRAIMNYQLGFNQVTAHPSCVNEITLSLNNRSARTKALVLELLAAVCLVRGGHEMILAAFNNFREVCGEKNRFEKLMEYFRN-EESNIDFMVACMQFINIVVHSVEDMNFRVFLQYEFTQLGLDSYLEKLNMTESERLQIQIQAYLDNVFDVGAMLEDAEAKNTLMEHLEELQEQNTQLNTRLHQCEIEALEKTTDLEQQ---LIQSSKQVELLKESVKEAQTQLQQLQLQQQKDRQTRSETQQHTHTDRQQTQMQMEKMLQLLVERGLIRMERSASGALDLHIIAAANTT-------------------DKCSKETSPVPQSPPPPPVPAP------------------------------------PPPPPPP-------PLALAPPTSP--------FIGRTG-TIKTGVKGKQPIKTKYRMPLLNWQALMEEQVAGTVFTELDDQTVLQELNMDVFEELFKTKAQSAPVDVG-------TLKVKVAQKASSKISLLEPNRAKNLAITLRKAGMSTAQICTAIQTYNLELLKSDFLELLERFVPSDYELKLIQNYERSGRPLVELSEEDRFMMAFSKIPRLTQRISTLTFMGSFSESVLILKPQLNAVISASKSIRSSSKLKKILEIILAFGNYMNSGKRGSAYGFRLQSLDLLLDMKSTDRKQTLLHFIVSIIQDKYPQLSNFHTELHFLDKAALVSLDSVLSDVCSLQKGMDVVCKELEQQQN---SSVLTQFICTNRGLLDTLIKDSTTAQEAYQSVVEYFGENPKSTPPSAFFPVFTRFIKAYKLCEQEIDQ--RRKRLSDSE---ETADLKFSDAPVHRQKP------LRLPQLDLISELKRR----QMS-PLVREG-KDGAIEDIITDLRNQPYIRADGGRRSAKWK-PAQQLA-VSTDISL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUC6-1", "uniprot_id": "FRL_DROME", "id": "Q9VUC6-1", "name": "Formin-like protein", "aln": "MGAVKSRTITSADVDADEQLQHPHSHAHHHSMRNGHQHNGSISSGTLQKQDLRYDIGCSSQYQHVRQPSLRSRSQQPMPTTDELDRRFAKVLASMDLPPDKAKLLRNYDDEKKWDMICDQEMVQAKDPPSHYLSKLRTYLDPKASRSHRLYLFYFLCQKRKMVGESTSTQVLRDLEISLRTNHIEWVKEFLDDTNQGLDALVDYLSFRLQMMRHEQRLQGVLCASEERLNLTNGGDGGEIVMGNSSSVSPGGGGGLLSHGNSTGHGLANGTLDSRQQHTMSYGFLRPTIADALDSPSLKRRSRHIAKLNMGAATDDIHVSIMCLRAIMNNKYGFNMVIQHREAINCIALSLIHKSLRTKALVLELLAAICLVKGGHEIILGSFDNFKDVCQEKRRFQTLMEYFMNFEAFNIDFMVACMQFMNIVVHSVEDMNYRVHLQYEFTALGLDKYLERIRLTESEELKVQISAYLDNVFDVAALMEDSETKTSALERVQELEDQ----LEREIDRNSEFLYKYAELESESLTLKTEREQLAMIRQKLEEELTVMQRMLQHNEQELKKRDTLLHT-----------KNMELQTLS-RSLPRSASSGDGSLANGGLMAGSTSGAASLTLPP-----PPPPMPASPTASSAAPPPPPPPAPPAP---------------PPPPGFSPLGSPSGSLASTAPSPPHAPP------MLSSFQPPPPP---------VAGFMPAPDGAMTIKRKVPTKYKLPTLNWIALKPNQVRGTIFNELDDEKIFKQIDFNEFEERFKIGIGGALRNGSNGTEVDGSLQSSKRFKRPDNVSLLEHTRLRNIAISRRKLGMPIDDVIAAIHSLDLKKLSLENVELLQKMVPTDAEVKSYKEYIIERKDQQLLTEEDKFMLQLSRVERISSKLAIMNYMGNFVDSVHLISPQVQSIAGASTSLKQSRKFKAVLEIVLAFGNYLNSNKRGPAYGFKLQSLDTLIDTKSTDKRSSLLHYIVATIRAKFPELLNFESELYGTDKAASVALENVVADVQELEKGMDLVRKEAELRVKGAQTHILRDFLNNSEDKLKKIKSDLRHAQEAFKECVEYFGDSSRNADAAAFFALIVRFTRAFKQHDQENEQRLRLEKAAALAASKKENDQVLMRNKVNQKKQQLPSNGALSLQEAVINELKSKAHSVREKKLLQQDEVYNGALEDILLGLKSEPYRRADAVRRSQRRRIDNNRLSRTLEEMDC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * ::*: : . . : .: * *: **:.** .* .*:*****. ** :**.****:::**** .*.*:**: *:.**:: :: . :: * *** ****:** ******* *.:***:: *.***.*::**:* : :: : *: . :: . ..* . :. : . : . * ** ::: :.:*:.********* : **. * * .:* *:*** ::. ************:***:***::**.:*:**::** *:.**:.***** : * ***********:********:**:**.****** **** ***::.:***:.*::**.*****:***.:::*::*:*.: :*:::**::* * : : : : * ::**.: * ::: ::: ..* . : :. : :: * :.* * . .. : : . :: . :.. * ..***. * * .** .** . **..* :. .:. *: : **:::* *** ** .*: **:*.**:*:.:::::::. *** ** .. : . :*: . * . : *:* .* :*:**: ** .: : **.: :*: * : :*** :::*:: * . .: . : *:***:**: :*:: *:..:: :.::*.* ::. :: **:::: .** *::.* *:: :***:******:**.***.****:***** *:: ****::.:***::* * *:*:* .*.::*: ***. *:*:.*:.** .*::*:::. :* : . :* :*: . :..: * ****::. *****:..:.: .. **.:: ** :*:* :** :* :. : . . * * :*.*** : : . * : :**:***: ::. *: * :*: : :: ", "identical_positions": 343, "similar_positions": 341, "identity": "27.8%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130313-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BXU9-2", "uniprot_id": "CABP8_HUMAN", "id": "Q9BXU9-2", "name": "Calcium-binding protein 8", "aln": "-------------------------MRLPEQPGEGKPENE-KKGDGGALGG--GEEPPRSQ-APDFP----TWEKMPFHHVTAGLLYKGNYLNRSLSAGSDSEQLANISVEELDEIREAFRVLDRDGNGFISKQELGMAMRSLGYMPSEVELAIIMQRLDMDGDGQVDFDEFMTILGPKLVSSEGRDGFLGNTIDSIFWQFDMQRITLEELKHILYHAFRDHLTMKDIENIIINEEESLNETSGNCQTEFEGVHSQKQNRQTCVRKSLICAFAMAFIISVMLIAANQILRSGME", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JJG7-1", "uniprot_id": "CABP8_MOUSE", "id": "Q9JJG7-1", "name": "Calcium-binding protein 8", "aln": "-------------------------MRLPEQPGDGKPENE-TKGDQETPER--GEEPRRSP-APDFP----TWEKMPFHHVTAGLLYKGNYLNRSLSAGSDSEQLANISVEELDEIREAFRVLDRDGNGFISKQELGMAMRSLGYMPSEVELAIIMQRLDMDGDGQVDFDEFMTILGPKLVSSEGRDGFLGNTIDSIFWQFDMQRVTLEELKHILYHAFRDHLTMKDIENIIINEEESLNETSGNCQTEFEGVHSQKQNRQTCVRKSLICAFAMAFIISVMLIAANQILRSGME", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LCV6-1", "uniprot_id": "A0ABK0LCV6_RAT", "id": "A0ABK0LCV6-1", "name": "", "aln": "MYPQISDHITLDPRCGCLSNLEMESLRMRQRGTKKPPKGERSHGEAQPLTSPPGKSPPNPK-SLDLDCFATPREKMPFHHVTAGLLYKGNYLNRSLSAGSDSEQLANISVEELDEIREAFRVLDRDGNGFISKQELGMAMRSLGYMPSEVELAIIMQRLDMDGDGQVDFDEFMTILGPKLVSSEGRDGFLGNTIDSIFWQFDMQRVTLEELKHILYHAFRDHLTMKDIENIIINEEESLNETSGNCQTEFEGVHSQKQNRQTCVRKSLICAFAMAFIISVMLIAANQILRSGME", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9PIG6-1", "uniprot_id": "A0A8M9PIG6_DANRE", "id": "A0A8M9PIG6-1", "name": "", "aln": "---------------------------MEVTNLDPDPRAEGTEGDEGLGSP--GKEPVVLEYAVDFDS---YGEKMPFHHVTAGLLYKGNFLSRSLSEHSNSEQLANISVEELDEIREAFRVLDRDGNGFISKQELGMAMRSLGYMPSEVELAIIMQRLDMDGDGQVDFDEFMTILGPKLLSSETREGFLGNTIDSIFWQFDMQRITLEELKHILFHAFRDHLTMKDIENIIINEEESLNENSGNCQTEFEGVHPKKKNRQTCVRKSLICAFAMAFIISVMLIAANQMLRNGME", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *. * ..*: *:.* : *: *****************:*.**** *:*******************************************************************************:*** *:******************:*********:*************************.************.:*:*****************************:**.***", "identical_positions": 211, "similar_positions": 23, "identity": "71.77%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130320-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q1A3B0-1", "uniprot_id": "CERS3_MOUSE", "id": "Q1A3B0-1", "name": "Ceramide synthase 3", "aln": "-------------------------MFQTFRKWFWSERYWLPPTIKWSDLEDHDGLVFVKASHLYITIPYAFLLMVVRYFFEKFVATPLANALGIKK-TQHKIKPNAILENFFKHSTSKPSHTDIYGLAKKCNLTERQVERWLRIRQKQNKPCRLQKFQESCWRFTFYLLITMAGAVFLYDKPWAYDLWEVWNDYPRQPLLPSQYWYYILEMSFYWSLVFSLSTDIKRKDFLAHVIHHLAAISLMSFSWCANYIRSGTLVMFIHDISDIWLESAKMFSYAGWKQTCNTLFFIFTVVFFISRFIIFPFWILYCTLILPLHYLEPFFSYIFLNLQLMILQGLHVYWGYFILKMLNRCIFTQNVQDVRSDNEEEEEEEEEEEAESTKGKETEYLKNGLGTNRHLIANGQHGR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IU89-1", "uniprot_id": "CERS3_HUMAN", "id": "Q8IU89-1", "name": "Ceramide synthase 3", "aln": "-------------------------MFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLLLIIRRVFEKFVASPLAKSFGIKE-TVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLTERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGYPKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIRSGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLILPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEEEEEEEEATKGKEMDCLKNGLRAERHLIPNGQHGH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G368-1", "uniprot_id": "A0AC58G368_DANRE", "id": "A0AC58G368-1", "name": "", "aln": "MLKGMSRYTIGLSYSKGQNISYKMLVIGTLGEWFWWDRLWLPGNLTWADLKDEDGLVYARPSHLYITLPYALIFLMVRYLFERLIATPLAASLGITEKTRHRVEHNTVLEQHFRTKSKNPGQADIDGLCKKCGWSSRQVERWFRRRRNQDRPGVLKKFREASWRMIFYLLAFIGGIIALYDKPWFYNVPEVWSDYPKQSMLDSQYWYYTVEMSFYLSLVLRITFDVKRKDFKEQIIHHWATLTLLAFSWCGNYIRVGTLVLLIHDSSDILLESAKIFNYAKWFKTCNGIFVVFAAVFIVTRLIIFPFWIIHCTWVYPPLYYPPFFGYYFFNFMLIVLLMLHIFWAYLILRMVKMFLFGSLTKDERSDNEE-DEEDDGETSMTEDNDEHVKVTNGCRGG----GRANHH-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: *: :*** :* *** .:.*:**:*.****:.:.****:*:***::::::* .**:::*:*** ::**.: * ::: *::**:.*: .: :* ::** **.***. :.******:* *::*::* *:**:*:.**: ***: :.* ****** *:: ***..**:*.:* ****** :***** **:: : *:***** ::*** *:::*::****.**** ****:::** :** *****:*.** * :*** :*.:*:.:*:::*:*:*****::** : * : ***.* *:*: *::* **::*.* **:*:: :* . :* ***:*: :**:: * : ...* :.** ..:* ", "identical_positions": 173, "similar_positions": 132, "identity": "42.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130326-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z9D2-1", "uniprot_id": "D3Z9D2_RAT", "id": "D3Z9D2-1", "name": "FYVE and coiled-coil domain-containing protein 1", "aln": "MASSSTETQLQRIIRDLQDAVTELSNEFKEGGEPITDDSTSLHKFSYKLEYLLQFDQKEKASLLGSKKDYWDYFCACLAKVKGANDGIRFVRSISELRTSLGKGRAFIRYSLVHQRLADTLQQCFMNTKVTSDWYYARSPFLKPKLSSDIVGQLYELTEVQFDLASRGYDLDAAWPTFARRTLATS-SSYMWKPPSRSSSMSSLVSNY-LQTQEMASSLDLNSSLNNEALES-------FDEMRLELDQLEVREKQLQEHVQQLNRENQALRMTISKQGGQLQVEKETGYLAVEDSIDLVSLVAELQKQGEVTQAT---VKKLQTCLQALELAVDQKE-TSHSVLQ-----LENVAQALDAVRDSLGRKNQLLASLSECLTRAEKREHPSLDTKLHQEPVPTDLALKFQELKGKLQTLEGENTKAQELNRQQSLKLEQLAKELQLKEEARASLEH-LVKDAVPLQEELSGKKQESAQLRRQLQESLAHLSSVEEELAEARQQEKQHREEKQLLEQEAKSLTWQLQLLETQLGQVSQLVSDLEEQKKQLMQDKDHLSQKVGTLEQLAEAHGASKSKE-----------AVPPQAGEMPEKGQHCLQEEQVNNATVRGADQDE-LQKVNQELQKELQNMAVRNQLLEGKLQALQTDYKALQQREAAIQGSLASLEAEQASIRQLGNQMEASLLAVRKAKETMKAQVAEKEAALQSKEGECRQLQEEAEQCRLRTEAQAQELRALENQCQQQIQLIEVLSAEKGQQGLSLPQVNTA-----QLALSQAQLEIHQGEAQRLQNEVVDLQAKLQVALGDRDKLQSQLGVAEAVLGEHKTLVQQLKEQNEALNRAHIQELLQCSEREGILQEESIYKAQKQ---EQELRALQAELSQVRCSSEGAHLEHAELQDQLHRANTDTAELGIQVCALTAEKDRMEGALASLAQELQDSKEAALQERKGLELQVMQLQQEKESLQEKLKATEEAASSFSVLQAQLAQAEQLAQSLQEAAHQEQDALKFQLSAEIMDHQNRLKTANEECGSLRAQLEEQGQELQMTKEAVQELKITKATMEEKLNCTGSHLAECQATLLRKDEESAMLRINLERTQKELEKATSKFQEYYNKLCQEVTNRERNDQKMLADLDDLNRTKKYLEERLIELLRDKDALWQKSDALEFQQKLSAEEKCLGDMEANHCHDCKREFSWIVRRHHCRLCGRIFCYYCCNNYVVTKPSGKKERCCRACFQKFGESSGSPDSSGSGTSQGEPSPMVSPAEAAPQSIGSQGINPVCRPP--DDAVFDIITDEELCQIQESGSSLPETPTETDSMDPNMAEQDTTSNSLTPEDTEDMPLGQDAEICLLKSGELMIKLPLTVEEIASFGEGNRELFVRSSTYSLIPITVAEPGLTISWVFSSDPKSISFSVVFQETEDTPLDQCKVLIPTTRCNSHKESIRGQLKVRTPGIYLLIFDNTFSRFISKKVFYHLTVDRPVIY----DGSDFP---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDC1-1", "uniprot_id": "FYCO1_MOUSE", "id": "Q8VDC1-1", "name": "FYVE and coiled-coil domain-containing protein 1", "aln": "MASSSTETQLQRIIRDLQDAATELSHEFKEGGEPITDDSTSLHKFSYKLEYLLQFDQKEKASLLGSKKDYWDYFCACLAKVKGANDGIRFVRSISELRTSLGKGRAFIRYSLVHQRLADTLQQCFMNTKVTSDWYYARSPFLKPKLSSDIVGQLYELTEVQFDLAPRGYDLDAAWPTFARRTLATSTSAYMWKPPSRSSSMSSLVSNY-LQTQEMASSLDLNCSLNNEALES-------FDEMRLELDQLEVREKQLQERVQQLDRENQALRMLVSRQGGQLQVEKEMGYLAVEDSIGLVSLVAELQKQGDVSQAT---VKKLQSCLQALELNVDKKE-YSPSALQ-----LENMAKELDTVRGSLGRENQLLASLSERLARAEKGEKTPPDTELHQEPVPADLVLKFQELKGKLQALEGENTEAQELNRQQSIKLEQLAKELQLKEEARASLAH-LVKDVVPLQEELSGKKQESAQLRRQLQESLAHLSSVEEELAEARQQEKQHREEKQLLEQEATSLTWQLQLLETQLGQVSQLVSDLEEQKKQLMQERDHLSQRVGTLEQLAEVHG-------------------PPQSAEMPEKRQQCLREEQVNNSTVSEAEQE--------ELQKELQNMVDRNQLLEGKLQALQTDYKALQQREAAIQGSLASLEAEQASIRHLGNQMEASLLAVKKAKETMKAQVAEKEAALQSKESECQRLQEEADQCRLQAEAQAQELRALENQCQQQIQLIEVLSAEKGQQGLSLPQVNTD-----QLALSQAQLEIHQGEAQRLQNEVVDLQAKLQVALGDRDKLQSQLGVAETVLREHKTLVQQLKEQNEALNRAHVQELLQCSEREGILQEESIYKAQKQ---EQELRALQAELSQVRCSSEGAHLEHAELQDQLHRANTDTAELGIQVCALTAEKDRMEEALASLAQELQDSKEAALQERKGLELQVMQLQQEKEKLQEKVKAAEEAASSFSGLQAQLAQAEQLAQSLQETAHQEQDALKFQLSAEIMDHQNRLKTANEECGHLRAQLEEQGQQLQMTKEAVQELEITKAAMEEKLNCTSSHLAECQATLLRKDEESTMLQTSLERTQKELEKATSKIQEYYNKLCQEVTNRERNDQKMLADLDDLNRTKKYLEERLIELLRDKDALWQKSDALEFQQKLSAEEKCLGDMEVNHCHDCKREFSWIVRRHHCRICGRIFCYYCCNNYVVTKPSGKKERCCRACFQKFGEGSGSNDSSGSGTSQGEPSPMVSPAEASPQSIGSQGINSVCRPP--DDAVFDIITDEELCQIQESGSSLPETPTETDSMDPNTAEQDTTSNSLTPEDTEDVPMGQDAEICLLKSGELMIKLPLTVEEVASFGEGSRELFVRSSTYSLITITVAEPGLTISWVFSSDPKSISFSVVFQETEDTPLDQCKVLIPTTRCNSHKENIRGQLKVRIPGIYLLIFDNTFSRFISKKVLYHLTVDRPVIY----DGSDFP---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQS8-1", "uniprot_id": "FYCO1_HUMAN", "id": "Q9BQS8-1", "name": "FYVE and coiled-coil domain-containing protein 1", "aln": "MASTNAESQLQRIIRDLQDAVTELSKEFQEAGEPITDDSTSLHKFSYKLEYLLQFDQKEKATLLGNKKDYWDYFCACLAKVKGANDGIRFVKSISELRTSLGKGRAFIRYSLVHQRLADTLQQCFMNTKVTSDWYYARSPFLQPKLSSDIVGQLYELTEVQFDLASRGFDLDAAWPTFARRTLTTGSSAYLWKPPSRSSSMSSLVSSY-LQTQEMVSNFDLNSPLNNEALEG-------FDEMRLELDQLEVREKQLRERMQQLDRENQELRAAVSQQGEQLQTERERGRTAAEDNVRLTCLVAELQKQWEVTQATQNTVKELQTCLQGLELGAAEKEEDYHTALRRLESMLQPLAQELEATRDSLDKKNQHLASFPGWLAMAQQKADTASDTKGRQEPIPSDAAQEMQELGEKLQALERERTKVEEVNRQQSAQLEQLVKELQLKEDARASLER-LVKEMAPLQEELSGKGQEADQLWRRLQELLAHTSSWEEELAELRREKKQQQEEKELLEQEVRSLTRQLQFLETQLAQVSQHVSDLEEQKKQLIQDKDHLSQQVGMLERLAGPPGPELPVAGEKNEALVPVNSSLQEAWGKPEEEQRGLQEAQLDDTKVQEGSQEEELRQANRELEKELQNVVGRNQLLEGKLQALQADYQALQQRESAIQGSLASLEAEQASIRHLGDQMEASLLAVRKAKEAMKAQMAEKEAILQSKEGECQQLREEVEQCQQLAEARHRELRALESQCQQQTQLIEVLTAEKGQQGVGPPTDNEARELAAQLALSQAQLEVHQGEVQRLQAQVVDLQAKMRAALDDQDKVQSQLSMAEAVLREHKTLVQQLKEQNEALNRAHVQELLQCSEREGALQEERADEAQQR---EEELRALQEELSQAKCSSEEAQLEHAELQEQLHRANTDTAELGIQVCALTVEKERVEEALACAVQELQDAKEAASREREGLERQVAGLQQEKESLQEKLKAAKAAAGSLPGLQAQLAQAEQRAQSLQEAAHQELNTLKFQLSAEIMDYQSRLKNAGEECKSLRGQLEEQGRQLQAAEEAVEKLKATQADMGEKLSCTSNHLAECQAAMLRKDKEGAALREDLERTQKELEKATTKIQEYYNKLCQEVTNRERNDQKMLADLDDLNRTKKYLEERLIELLRDKDALWQKSDALEFQQKLSAEERWLGDTEANHCLDCKREFSWMVRRHHCRICGRIFCYYCCNNYVLSKHGGKKERCCRACFQKLSEGPGSPDSSGSGTSQGEPSPALSPASPGPQATGGQGANTDYRPP--DDAVFDIITDEELCQIQESGSSLPETPTETDSLDPNAAEQDTTSTSLTPEDTEDMPVGQDSEICLLKSGELMIKVPLTVDEIASFGEGSRELFVRSSTYSLIPITVAEAGLTISWVFSSDPKSISFSVVFQEAEDTPLDQCKVLIPTTRCNSHKENIQGQLKVRTPGIYMLIFDNTFSRFVSKKVFYHLTVDRPVIY----DGSDFL---------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HXM1-1", "uniprot_id": "A0AC58HXM1_DANRE", "id": "A0AC58HXM1-1", "name": "", "aln": "-MSTVGENQLQRIIRDLHDAVSELSKEHCDTEDPITDDSSSLHKFCFKLEYLLQFDQKERTTFLGSRKDYWDYFCDCLAKIKGANDGIRFVKSIPELKTSLGKGRAFIRYCLVHQRLADTLQQCLINLKITSEWYYERSPFLKSHLNIDIINHLYELNEVQFDVASRGYDLDSQWPTFARRTLGSAVSPHVWKPPSRCSSVNSLVSSYTQQVQDFLPGQDFGSSLLGDLGELGELTCSTSEDLRIELDQSELKQQQLKEKIQLLTDEAADLRVVIKDLQEQLLAKGSDQEKAGEQQQEVVKAVRECADLLSTTTQG---LEALRTSERNLEAKLSVAE----------------------------NRNMELLAKLDGALS-----------EKGQQAANYCDSAWTIQELLTKLKEAEQERIEAKRESEDRARIAERLSQEIKLQEGKLKEMEGNLDMCRVTADKERTTATQQADELQMTINRLQGALSLKERETGNLR---TQLQDVQKALEAQQDQMEEHMKKIQEEMQRKSVLEEQLNAKMNELSVNTQKMRQLENHNQRLIVENQ-----------------SFQAQAKKLEEYKSQCTSLMEINAKLIQTVKRNE-------DSSKELSEIKTT---LEKELKTLQASERQLRTR------------LESAGLTVESQNLEECIENGQTDNEDVLEKLNESTTAPQKNKRTTSGLLQEANECSKTDHVESTTR----------------------------------------LALAEAQLELNMKEVSRLQDEVLELRAQLLVISEERMKIQALQEVTEASREDLRAQTEQLKSQVEELNRRHVEELLRCHEREETLGKERDMEAKMRAEIQTSMTSMKEECHALKKHNSTLALENGEAREALHRANTETAELGVHVCMLTGQNEEAKLRWEELSNKLQELQMEAQEEVKTLSDSMESLRKDNAGLKEQVKQMEGLQEALQKLQEKLERAEDEARSLQEIRQREVDTLRSQLSDEAAHHQSQVQGMSEDMDALRKRLDIEVEKVSSLEAKVLKLESLNSGQSQMIEKTTALIGDSETIIYQKEEQIKNLKVDLSRAEKELVLAQQSCQELGVNLSRSAMEKQAVELKMSAELDDLYRTKKNLEERLIELIREKDALWQKSDALEFEQKRRAEEQT--DRDVTHCLSCKSQFSWMLRRYNCRFCGRPFCYSCCS-------FGGKDRCCKSC---------STHSERQQADQGSPSHSTYSPISSPNQTSTPGVPWILKSPRPDDMAYDIITEDEVNRVHDS-----DSSSYTTALSPETQQLSSSDVTSTEDSDELIGSVQDSEICLLKSGERTLSVPFSVDDVMHFGSKSKELFIKSSCYSVILISAAHPGPSIGWTFSSEPKSIAFSVVYRETTDTPLEQAKVLIPLTRCRSHKETIQGQLKVRNPGQYTLIFDNSFSRFVSKKVQYKLSIEMPEVTGLLVQGYGCLKAKYVMLLSELTNSSWRNVEVDVLWLPQRLSFSSVLKIEIQKRITEKACKVGHIDSSTVIVVNSSMRLKSFDVHGELLVKLVTVGKPSTWREEKNLYRFGTKFGLKPYCRLLSVSQVHRRTSRANWTNW", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *.*********:**.:***:*. : :******:*****.:************::::**.:******** ****:**********:**.**:************.*************::* *:**:*** *****:.:*. **:.:****.*****:*.**:***: ********* :. *.::******.**:.****.* *.*:: .. *:...* .: * :::*:**** *::::**:*::* * * ** :. ** .: . * *:. :. * * . ..: :: *::. : ** * .:: : **.: *: : :* . * . :*** **: * *. :.:. ..::: *:* :*::*:* .: * .. ::* : *:: :* ::. . * *.* .: * .* :: :: ** : .: ::: :: :: : * .:*: : ::* : ::: * . ::* :: * .: ::: : .:: : .***.:: ** :*::**:. : *: * *.*.: .:::* .: :. :* : :: *. : *.:: * :*.::* ... ***::****:: *..*** :*::*:*:: . :: *:*: ::*: : :: .:***.* * *** *::***:* *** * :* :*: : : .: ::: * : .. **:.* :: ******:*****::** ** :::. : ::**: : * .* : *. .: *:::: *:*::* : :: ** :* :**: *:**** ::* ::*: *** * .:*.::: .*: ** :*: : .::. : * :*: :: : :. * :.:.:: : :*::: *: .*.*::*** * . ** :*.:.. ::: : ** *:**** **** ********:*:*************:** ***: * :..** .** :***::**::**:*** *** **. * *:***::* * .*. . :.**.** .. ..*: . * :.* ** .:****::*: ::::* ::.: * ::.*: : .::. : * :. * : **:********* :.:*::*::: **. .:***::** **:* *:.*..* :*.*.***:****:****::*: ****:*.***** ***.****.*:****** ** * *****:****:**** *:*::: * : :* . ", "identical_positions": 496, "similar_positions": 444, "identity": "30.52%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130326-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NZQ3-1", "uniprot_id": "SPN90_HUMAN", "id": "Q9NZQ3-1", "name": "NCK-interacting protein with SH3 domain", "aln": "MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLEQD-VLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGPSASSVAVMTSSTSDHHLDAAAARQPNGVCRA----GFERQH----SLPSSEHLGADGGLYQIPLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSS--SPSEPGSSCSPTPPPVPRRG-------------THTTVSQVQPPPSKASAPEPPA--------EEEVATGTTSASDDLEALGTLSLGT-----------------------TEEKAAAEAAVPRTIGAELMELVRRNTGLSHELCRVAIGIIVGHIQASVPASSPVMEQVLLSLVEGKDLSMALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEGVIRCYLEELLHILTDADPEVCKKMCKRNEFESVLALVAYYQMEHRASLRLLLLKCFGAMCSLDAAIISTLVSSVLPVELARDMQTDTQDHQKLCYSALILAMVFSMGEAVPYAHYEHLGTPFAQFLLNIVEDGLPLDTTEQLPDLCVNLLLALNLHLPAADQNVIMAALSKHANVKIFSEKLLLLLNRGDDPVRIFKHEPQPPHSVLKFLQDVFGSPATAAIFYHTDMMALIDITVRHIADLSPGDKLRMEYLSLMHAIVRTTPYLQHRHRLPDLQAILRRILNEEETSPQCQMDRMIVREMCKEFLVLGEAPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9ESJ4-1", "uniprot_id": "SPN90_MOUSE", "id": "Q9ESJ4-1", "name": "NCK-interacting protein with SH3 domain", "aln": "MYRALYAFRSAEPNAMAFAAGETFLVLERSSTHWWLAARARSGETGYVPPAYLHRLQGMEQD-VLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGTSASSATVMTPSTSDHHLDAAVSRQPNGVCRT----GFERQH----SLPSSEHLGTDGALYQVP-------PQPRRAAPTTPPPPVKRRDREALVISGSGGRTAIPSGGSSVSSGSSASSTSMDTLYTGS--SPSELGPSCSPTPPPVPRRG-------------AHTTVSQPQPSPSKAPSPEPP---------TEEVAAETNSTPDDLEAQDALSPET-----------------------TEEKAAAETVVPRTIGAELMELVRRNTGLSHELCRVAIGVVVGHIQATVPASSPIMEQVLLSLVEGKDLSTALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEDVIRCYLEELLHILTDADPEVCKKMCKRSDFESVLALVAYYQMEHRASLRLLLLKCFGAMCSLDAAIISTLVSSVLPVELARDMQTDTQDHQKLCYSALVLAMVFSMGEAVPYAHYEHLGTPFAQFLLSIVEDGLPMDTTEQLPDLCMNLLLALNLHLTAPEQNVIMAALSRHTNVKIFSEKLLLLLNRGDDPVRIFRHEPQPPHSVLKFLQDVFSSSATAAIFYHTDMMALIDITVRQIADLSPGDKLRMEYLSLMHAVVRSTPYLQHRHRLSDLQATLRRILTEEEASPQCQMDRMIVQEMYKEFPDLGEVPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB13A8I5-1", "uniprot_id": "A0AB13A8I5_DANRE", "id": "A0AB13A8I5-1", "name": "", "aln": "MYHSLFSFSSAEQNALHFPAGEAFLILERSSAHWWLATRCSSGETGYIPAAYLQKIPAPEQDEVLQSIDRAIEAIHNVAMTNGGKYNLEQRDVLQKLIHHRKETLSRRSPTPSGVKSKIPSSSSE-ASLSQTPPPNGLSRTPPPNGLSRAHSCQGSKPMSERTASVPGLYQVP-------PHPRRAAPDTPPALDKQRN-DPPMSLRVSSTSPTPSSVAPPGPSLSISSASLDSGSSQSGVSSDVSLPSVSSTPPPVPKRGKAPPPPPPDQSPQEEPVKKSPAPQPIRSQAPPPPPDLSIKTLTPQPISSQAPPPPTDLSKESPVPQPMGLQPAAEPHPEVEWPLAPPPVSLSPPAGSAQCALPLTIGAELTELVRRNTGLSCELSRVAVGVVVGRLQGALPGAQVQLEQVLQSLA----LSTDLPLGQVCHDQQRLQVIFGDLARHREDSQQRSWALHEDHALIACYLEELLQILTDADAEVCRKMCRVNEFEPVLSLVSYYQMEHRVSLRLWLLKVFGAMCGLDAALISTLLNSVLTMELARDLQTDTDEHEKMCYSALLMAMVFSTGEQIPLHHYEHLNAGFLQFLLDVIEDGLPTDSTEQLPDLFINVLLAFNLHLSVPDSNIVMQTLMKRDNAKILSEKLLLLLNRGEDPVCVFSHAPAAPHAVVKFLQDVFSSADSAQIFYRSDLMVLIDITVRQISDLEPGDRMRAQYLSLMLSVMRCSEYQEHRHRLADLRAALQRILGEEESG---AAERSIVLQIYEEFPDTCSS--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::*::* *** **: *.***:**:*****:*****:*. ******:*.***::: . *** ***:*******:**.** :****.****.****************..:.*.. .*:*.. . : : ***:.*: *:.* * * * **: .: .***:* *:****** ***. *:*: :. : .. .. **. . ... * **:*:*: : * *.. .* *.******:** ... .. * * :: :* ** : ::: : ... **. ..:. : .:*: .:* ****** ********** **.***:*::**::*.::*.:. :**** **. ** ** **********:***.****:::*:*******:**. :* *******:******.***:***: .:**.**:**:*******.**** *** *****.****:****:.***.:*****:****::*:*:*****::***** ** :* *****.: * ****.::***** *:******* :*:***:****...:.*::* :* :: *.**:***********:*** :* * * .**:*:*******.*. :* ***::*:*.*******:*:**.***::* :***** :::* : * :*****.**:* *:*** ***:. :* ** :: :** . ", "identical_positions": 390, "similar_positions": 199, "identity": "50.19%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130329-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q924I2-1", "uniprot_id": "M4K3_RAT", "id": "Q924I2-1", "name": "Mitogen-activated protein kinase kinase kinase kinase 3", "aln": "-------MNP---GFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKHANIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKLKWSNSFHHFVKMALTKNPKKRPTAEKLLQHPFVTQPLTRSLAIELLDKVNNPDHSTYHDFDDDDPEP---------------------------LVAVPHRIPS--TSRNVREEKTRSEINFG-------------QVKFDPPLRKETEP------------------------------------------------HHEL---------------------DLQLEYGQGHQSNYFLGGNKSLLKSVEEELHQR---------------------GHVAHLEDD-------------------EGDDD------------------------------------------DSKHSTLKAKVPPPLPPKPKSISIPQDTH---------------------------SSEDS----NQGTIKRCPSSGSPAKPSH-VPPRPPPPRLPPQKPAVLGNG----------------------------VSSFQLNG------------------------ERDGSVHQQQSEQRGTNLSR-------------------------------------------------KEKKDVPKPISNGLPPTPKVHMGACFSKVFNGCPLKIHCATSWINPDTRDQYLIFGAEEGIYTLNLNELHETSMEQLFPRRCTWLYVMNNCLLSVSGKASQLYSHNLPGLFDYARQMQKLPVAIPAHKLPDRILPRKFAVSAKIPETKWCQKCCVVRNPYTGHKYLCGALQTSIVLLEWVEPMQKFMLIKHIEFPMPCP------------LRMFEMLVVPEQEYPLVCVGVSRGRDFNQVVRFETVNPNSTSSWFTESDTP------------QTNVTHVTQLERDTILVCLDCCIKIVNLQGRLKSSRKLSSELTFDFQIESIVCLQDSVLAFWKHGMQGRSFRSNEVTQEISDNTRIFRLLGSDRVVVLESRPTDNPTANS----NLYILAGHENSY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JP0-1", "uniprot_id": "M4K3_MOUSE", "id": "Q99JP0-1", "name": "Mitogen-activated protein kinase kinase kinase kinase 3", "aln": "-------MNP---GFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKLKWSNSFHHFVKMALTKNPKKRPNAEKLLQHPFVTQPLTRSLAIELLDKVNNPDHSTYHDFDDDDPEP---------------------------LVAVPHRIPS--TSRNVREEKTRSEINFG-------------QVKFDPPLRKETEP------------------------------------------------HHELPDSDGFFDSSEEIYYTARSNLDLQLEYGQGHQSHCFLGGNKSLLKSVEEELHQR---------------------GHVAHLEDD-------------------EGDDD------------------------------------------DSKHSTMKAKVPPPLPPKPKSIFIPQDTH---------------------------SAEDG----NQGTIKRCPSSGSPAKPSH-VPPRPPPPRLPPQKPAVLGNG----------------------------VNSFQLNG------------------------ERDGSLYQQQSEQRGTNLSR-------------------------------------------------KEKKDVPKPISNGLPPTPKVHMGACFSKVFNGCPLKIHCATSWINPDTRDQYLIFGAEEGIYTLNLNELHETSMEQLFPRRCTWLYVMNNCLLSVSGKASQLYSHNLPGLFDYARQMQKLPVAIPAHKLPDRILPRKFAVSAKIPETKWCQKCCVVRNPYTGHKYLCGALQTSIVLLEWVEPMQKFMLIKHIEFPMPCP------------LRMFEMLVVPEQEYPLVCVGVSRGRDFNQVVRFETVNPNSTSSWFTESDAP------------QTSVTHVTQLERDTILVCLDCCIKIVNLQGRLKSSRKLSSELTFDFQIESIVCLQDSVLAFWKHGMQGRSFRSNEVTQEISDNTRIFRLLGSDRVVVLESRPTDNPTANS----NLYILAGHENSY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IVH8-1", "uniprot_id": "M4K3_HUMAN", "id": "Q8IVH8-1", "name": "Mitogen-activated protein kinase kinase kinase kinase 3", "aln": "-------MNP---GFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVNTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKHPNIVAYFGSYLRRDKLWICMEFCGGGSLQDIYHVTGPLSELQIAYVSRETLQGLYYLHSKGKMHRDIKGANILLTDNGHVKLADFGVSAQITATIAKRKSFIGTPYWMAPEVAAVERKGGYNQLCDLWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKMKWSNSFHHFVKMALTKNPKKRPTAEKLLQHPFVTQHLTRSLAIELLDKVNNPDHSTYHDFDDDDPEP---------------------------LVAVPHRIHS--TSRNVREEKTRSEITFG-------------QVKFDPPLRKETEP------------------------------------------------HHELPDSDGFLDSSEEIYYTARSNLDLQLEYGQGHQGGYFLGANKSLLKSVEEELHQR---------------------GHVAHLEDD-------------------EGDDD------------------------------------------ESKHSTLKAKIPPPLPPKPKSIFIPQEMH---------------------------STEDE----NQGTIKRCPMSGSPAKPSQ-VPPRPPPPRLPPHKPVALGNG----------------------------MSSFQLNG------------------------ERDGSLCQQQNEHRGTNLSR-------------------------------------------------KEKKDVPKPISNGLPPTPKVHMGACFSKVFNGCPLKIHCASSWINPDTRDQYLIFGAEEGIYTLNLNELHETSMEQLFPRRCTWLYVMNNCLLSISGKASQLYSHNLPGLFDYARQMQKLPVAIPAHKLPDRILPRKFSVSAKIPETKWCQKCCVVRNPYTGHKYLCGALQTSIVLLEWVEPMQKFMLIKHIDFPIPCP------------LRMFEMLVVPEQEYPLVCVGVSRGRDFNQVVRFETVNPNSTSSWFTESDTP------------QTNVTHVTQLERDTILVCLDCCIKIVNLQGRLKSSRKLSSELTFDFQIESIVCLQDSVLAFWKHGMQGRSFRSNEVTQEISDSTRIFRLLGSDRVVVLESRPTDNPTANS----NLYILAGHENSY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U0S1-1", "uniprot_id": "A0AB32U0S1_DANRE", "id": "A0AB32U0S1-1", "name": "Mitogen-activated protein kinase kinase kinase kinase", "aln": "-------MNS---SFDLSRRNPQEDFELIQRIGSGTYGDVYKARNVTTGELAAIKVIKLEPGEDFAVVQQEIIMMKDCKHSNIVAYFGSYLRRDKLWISMEYCGGGSLQDIYHVTGPLTESQIAYVTRETLQGLYYLHNKGKMHRDIKGANILLTDNGYVKLADFGVSAQITATLAKRKSFIGTPYWMAPEVAAVERKGGYNHLCDIWAVGITAIELAELQPPMFDLHPMRALFLMTKSNFQPPKLKDKVKWTNNFHNFVKLALTKNPKKRPPADKLLQHPLVSQPLSRILAIELLDKANNPDHSSYTDLDDDDPEPEFKYRGLFLPVSPLSRRVLRFAARRKPPVSVPHRIRS--TSRTSREGKTLSEINFG-------------QVKFDPPLTTETKP------------------------------------------------HHEQLDTDDFLDCAEEIYYTARSNLDLQMDYEQGSPKGSILGGNKSLLKSVEEELQQR---------------------GHEAHLEDDD------------------EGEDDGDDHDDELQ---------------------------------HTKSSTMRPKVPPPLPPKPKPSPGPHQSP---------------------------SADPDRN--NQGTIKRCPEPESPARSSTSVPPRPPPPRLPAYKLSSLGNETHQEEHGLWGAQGDAGICSQFDQRLQVSFDDEENHD------------------------EEENSNGISPSEHSASTERQST---------------------------------------MPPAVPVPKDKKDFPKPISNGLPPTPKVHMGACFSKVFNGCPLKIHCATSWINPDTRDQYLIFGAEEGIYTLNLNELHETSMEQLVPRRCTWLYVLSNSLLSISGKACHLYSHSLSGLFEHARQMQKLPVSIPTHKLPDKMIPRKFSVSNKIPETKGCQKCCVVRNPYTGHKYLCGAFQSSIALFEWVETMQKFMLVKSIDFPLPCP------------LEVFEMLVVPEHQYPLICIAVSKGTELNQVVRFETLNPNSTSNWF-DSDTP------------QSCVIHVTQLERDTILVCLDRCIKIVNLQGRLKSSRKLSAELTFNFQIESIVCLQDSVLAFWRHGMQGRSFKSNEITQEISDNSRIFRLLGSDRVVVLESRPTDNPTAHS----NLYILAGHENSY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZBH7-1", "uniprot_id": "A1ZBH7_DROME", "id": "A1ZBH7-1", "name": "non-specific serine/threonine protein kinase", "aln": "MAAAHSHHNANMLSSDISRRNPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDIQIIQQEIIMMRDCRHPNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSMGKMHRDIKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFIKTALTKNPKKRPTAERLLQHPFVQCEMSLRVAKELLQKYQSPNPQFYYYLDGDEESVAG----------VPQRIASKMTSRTNGVPAQNHTLKTGMTTNSTWNERSSSPETLPSDMSLLQYIDEELKLRATLPLNNDTKDPLGAECSCSSHNGGAAGGGGGGGVGVGAGGAAANGSSSSSGGATVGTTHHQHQQHHQHHHHPNHLHQHQSHQLPQQQQQQSHQAAQQEHHHHHPMTSSISSGLVTANANNISSSASLASMPGLSAYLGMRSHVVGHMGMGFGMGLGMSNLRTTSIDADDDELVAADVAMNNAAAAVPGNGSGAGNGSGSGCSASAAHYLRYSSNYRSAAAAQASQAAHPHVNSNSNSNNGHGHAPITSSISSSASSASFYNRLLLLDNSSGDAVVGGNGGGSSNISSSGGASSGTNGLLDKHELDALPQAATKSAGDG--FSHSNSPTANSGAGATGSRDNDGPSSSNSSHLYQNLLRSSSGETPAGSSSAGNNCDYRHENNQNGLEDSPRRHSSMDQLIGLLENMGKSPRTRSLSDGGTQDDDEAEKEAQPDLLNNTPPVPPKRSHKRRHTPPRPISNGLPPTPKVHMGACFSKIFNGCPLRVHCTASWIHPETRDQHLLIGAEEGIYNLNMNELHDAAIDQLFPRRTTWLYVIKDVLMSLSGKSCQLYRHDLVALHS----KQTVRFSLHMNKIPERLVPRKFALTTKVPDTKCCTQCCVTRNPYNGYKYLCGATPSGIFLMQWYDPLNKFMLLKQCEWPAISIQGGGHGCVQNGHTPVFEMIITPELEYPIVCTGVR--KAMNGCLKLELINMN-SASWFHSEDLEYDAMATMVPRRDLLKVVRVHQVEKDAILVCYGNLIQVVTLQGNPKQHKKMVSQLNFDFNVDSIVCLPDSVLAFHKHGMQGKSLRNGEVTQEIKDMSRTYRLLGSDKVVALESQLLRTGSLGSEEGHDLYILAGHEASY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. . *:******:::****:************:.: :.************.:*: ::*******:**:*.**:**:***********.**:**********:*****:* ****: ****:** ***. ***************: * ***************: **************************:***:** **************************:**.*:**.*::* **: .**:*:* ********** *::*****:* :: :* ***:* :.*: . * :*.*: . : * : : *:.. : :: * .: ::: ** .:*: **: * : . ::.: .*:.. * * :*: .. :.:** . *: .: . . *: :. .:: *: * * .. . . ..: : : : ** *: .. . ..:.. . . : :. : * :: *:********************:******::**::***:*:****:*::*******.**:****:::::**.*** *****:.: *:*:***:.:** *.* .*.. *.: .:: :*:*::::****::: *:*:** * :***.****.*:****** :.* *::* :.::****:* ::* . :***::.** :**::* .* :* :::* :* * ::.** ..* * :* *:*:*:**** . *::*.***. *. :*: ::*.*:*:::***** ****** :*****:*::..*:****.* :* :******:**.***: . : * :******** **", "identical_positions": 431, "similar_positions": 249, "identity": "34.84%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130403-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35568-1", "uniprot_id": "FBLN3_RAT", "id": "O35568-1", "name": "EGF-containing fibulin-like extracellular matrix protein 1", "aln": "-------------------------------------------------------------MLQTVFLTMLTLALVKSQVTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETPAAEASSGAATGTIAARSMATSGVIPGGGFIASATAVAGPEVQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTSGTHNCRLDQVCINLRGSFTCHCLPGYQKRGEQCVDIDECSVPPYCHQGCVNTPGSFYCQCNPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTN-ECREDEMCWNYHGGFRCYPQNPCQDPYVLTSENRCVCPVSNTMCRDVPQSIVYKYMNIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLTGPREHIVGLEMLTVSSIGTFRTSSVLRLTIIVGPFSF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BPB5-1", "uniprot_id": "FBLN3_MOUSE", "id": "Q8BPB5-1", "name": "EGF-containing fibulin-like extracellular matrix protein 1", "aln": "-------------------------------------------------------------MLQTLFLTMLTLALVKSQYTEETITYTQCTDGYEWDPIRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEHPQQETPAAEASSGATTGTVAARSMATSGVVPGGGFMASATAVAGPEVQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTSGTHNCRTDQVCINLRGSFTCQCLPGYQKRGEQCVDIDECTVPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYEVVRSRTCQDINECETTN-ECREDEMCWNYHGGFRCYPRNPCQDHYVLTSENRCVCPVSNTMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATMIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREYIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12805-1", "uniprot_id": "FBLN3_HUMAN", "id": "Q12805-1", "name": "EGF-containing fibulin-like extracellular matrix protein 1", "aln": "-------------------------------------------------------------MLKALFLTMLTLALVKSQDTEETITYTQCTDGYEWDPVRQQCKDIDECDIVPDACKGGMKCVNHYGGYLCLPKTAQIIVNNEQPQQETQPAEGTSGATTGVVAASSMATSGVLPGGGFVASAAAVAGPEMQTGRNNFVIRRNPADPQRIPSNPSHRIQCAAGYEQSEHNVCQDIDECTAGTHNCRADQVCINLRGSFACQCPPGYQKRGEQCVDIDECTIPPYCHQRCVNTPGSFYCQCSPGFQLAANNYTCVDINECDASNQCAQQCYNILGSFICQCNQGYELSSDRLNCEDIDECRTSSYLCQYQCVNEPGKFSCMCPQGYQVVRSRTCQDINECETTN-ECREDEMCWNYHGGFRCYPRNPCQDPYILTPENRCVCPVSNAMCRELPQSIVYKYMSIRSDRSVPSDIFQIQATTIYANTINTFRIKSGNENGEFYLRQTSPVSAMLVLVKSLSGPREHIVDLEMLTVSSIGTFRTSSVLRLTIIVGPFSF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T0U7-1", "uniprot_id": "A0AB32T0U7_DANRE", "id": "A0AB32T0U7-1", "name": "", "aln": "MICSCINSLCNPRAFLQQRETTCSHSRTHTHTHTHTQLHQISSSSTHTAADLQHSSSLTPAEMWTVSLMMAALACVLSQEAEESVSYTRCTEGYEYDPFKEVCTDIDECVLVSDACKAGMKCINHYGGYLCLPQNAQIFINKENE-----------------------------------ASQSSDSVPQTHTETN-----------HRSAANGGS--QCSAGFTRDQHNYCHDVDECSQGLHTCGSDQICYNSRGSYSCQCQPGYQRHGEQCVDRNECLLSHYCMHRCVNTAGSYYCECNDGYQLASNNHSCVDVNECEVSQPCQHQCFNLLGSFICQCEQGYELGPDAVSCVDIDECSFSSYMCQYACVNSEGGYSCTCPDGYQIHRTRMCQDINECETAAHECREDEMCWNYYGGHRCYPRNPCLEPYVRTSENRCSC-QSAAACRGLPQSIVYKYMNMHSERSVPADIFQIQATNIFSSAHYTFRIKDGNDGGQFFLRRFSSAGAMLVLTQSLEGPQELIVDLEMITQHSLMNYRSSSLLRLTIIVGPFPF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: * * :** * ** :**:::**:**:***:**.:: *.***** :*.****.****:**********:.***::*:*: ** :: : *: :* * :* .:* . **:**: :.:** *:*:***: * *.* **:* * ***::*:* ****::****** :** :. ** : ****.**:**:*. *:***:**::***:***:.*: * :**:*:********:*****..* :.* ***** ***:*** ***. * :** **:**:: *:* *********: ***********:**.****:*** : *: *.**** * * : ** :*********.::*:****:******** *::.: *****.**:.*:*:**: *...*****.:** **:* **.***:* *: .:*:**:**********.*", "identical_positions": 261, "similar_positions": 118, "identity": "47.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130404-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O76031-1", "uniprot_id": "CLPX_HUMAN", "id": "O76031-1", "name": "ATP-dependent clpX-like chaperone, mitochondrial", "aln": "MPSCGACTCGAAAVRLITSSLASAQRGISGGRIHMSVLGRLG-TFETQILQRAPLRSFTETPAYFASKDGISKDGSGDGNKKSASEGSSKKSGSGNSGKGGNQLRCPKCGDLCTHVETFVSSTRFVKCEKCHHFFVVLSEADSKKSIIKEPESAAEAVKLAFQQKPPPPPKKIYNYLDKYVVGQSFAKKVLSVAVYNHYKRIYNNIPANLRQQAEVEKQTSLTPRELEIRRREDEYRFTKLLQIAGISPHGNALGASMQQQVNQQIPQEKRGGEVLDSSHDDIKLEKSNILLLGPTGSGKTLLAQTLAKCLDVPFAICDCTTLTQAGYVGEDIESVIAKLLQDANYNVEKAQQGIVFLDEVDKIGSVPGIHQLRDVGGEGVQQGLLKLLEGTIVNVPEKNSRKLRGETVQVDTTNILFVASGAFNGLDRIISRRKNEKYLGFGTPSNLGKGRRAAAAADLANRSG-ESNTHQDIEEKDRLLRHVEARDLIEFGMIPEFVGRLPVVVPLHSLDEKTLVQILTEPRNAVIPQYQALFSMDKCELNVTEDALKAIARLALERKTGARGLRSIMEKLLLEPMFEVPNSDIVCVEVDKEVVEGKKEPGYIRAPTKESSEEEYDSGVEEEGWPRQADAANS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JHS4-1", "uniprot_id": "CLPX_MOUSE", "id": "Q9JHS4-1", "name": "ATP-dependent clpX-like chaperone, mitochondrial", "aln": "MSSCGACTCGAAAARLLTTSLTSAQRGISCGRIHVPVLGRLGTTLDAQALRRAPLRTFSETPAYFASKDGANKDGSGDGNKKSVTEGSSKKSGSGNSGKGGNQLRCPKCGDLCTHVETFVSSTRFVKCEKCHHFFVVLSEADSKKSIIKEPESAAEAVKLAFQQKPPPPPKKIYNYLDKYVVGQSFAKKVLSVAVYNHYKRIYNNIPANLRQQAEAEKQTSLTPRELEIRRREDEYRFTKLLQIAGISPHGNALGASMQQQVNQQMPQEKRGGEVLDSSQDDIKLEKSNILLLGPTGSGKTLLAQTLAKCLDVPFAICDCTTLTQAGYVGEDIESVIAKLLQDANYNVEKAQQGIVFLDEVDKIGSVPGIHQLRDVGGEGVQQGLLKLLEGTIVNVPEKNSRKLRGETVQVDTTNVLFVASGAFNGLDRIISRRKNEKYLGFGTPSNLGKGRRAAAAADLANRSG-ESNTHQDIEEKDRLLRHVEARDLIEFGMIPEFVGRLPVVVPLHSLDEKTLVQILTEPRNAVIPQYQALFSMDKCELNVTEDALKAIARLALERKTGARGLRSIMEKLLLEPMFEVPNSDIVCVEVDKEVVEGKKEPGYIRAPSKESSEEEYDSGVEEDGWPRQADAANS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F9J1-1", "uniprot_id": "E7F9J1_DANRE", "id": "E7F9J1-1", "name": "ATP-dependent clpX-like chaperone, mitochondrial", "aln": "MS----CSC-RTAVRVIIKSVP---KGVCCSRVHVFSRSRSA-CDELHLPPVLNVRCFSQSVVCFSSKESPPRD--GDGGKKAVGESGKRASGAGGSGKGGSQLRCPKCGDPCTHVETFVSSTRFVKCEKCHHFFVVLSETDSKKGLNKETE-SSEHVKFALAQKPPPPPKKIYAYLDKFVVGQSYAKKVLSVAVYNHYKRIYNNLPAAGRQQAESEKQSSLSPRELEIRRREDEYRFTKLLQIAGISPHGNALGASVQQQTNQQAQQDKRGGDVLDSAHTDIKLEKSNIVLLGPTGSGKTLLAQTLAKCLDVPFAICDCTTLTQAGYVGEDIESVIAKLLQDANYSVEKAQQGIVFLDEVDKIGSVPGIHQLRDVGGEGVQQGLLKLLEGTIVNVPEKNSRKLRGETVQVDTTNILFVASGAFNGLDRIISRRKNEKYLGFGTPSNLGKGRRAAAAADLANTSGTEMDAMAEIEEKDRLLRIVEARDLIEFGMIPEFVGRLPVVVPLHSLDEEMLVQILTEPRNAVVPQYQALFSMDKCELNVTSDALRAIARLALERKTGARGLRSIMEKLLLEPMFEVPQSDIIAVELNKDVVQGKCEPRYIRTHPKET-EEEFE----EDNWPRHADAANN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. *:* :*.*:: .*:. :*:. .*:*: .* . : : :* *::: . *:**:. :* ***.**:. *...: **:*.*****.********* ****************************:****.: **.* ::* **:*: *********** ****:*****:*******************:** ***** ***:**:**********************************:***.*** *:****:****:: *********:*******************************************************.********************************************************************:********************************************** ** * :: :********* ******************************: ************:*****************.***:********************************:***:.**::*:**:** ** ***: .**: ***:: *:.***:*****.", "identical_positions": 491, "similar_positions": 83, "identity": "77.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130404-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYQ9-1", "uniprot_id": "D3ZYQ9_RAT", "id": "D3ZYQ9-1", "name": "E3 ubiquitin protein ligase", "aln": "MSGIGNKRAAGEPGTS-VPPEKKTAVED-------SG--TTVET-IKLGGVSSTEELDIRTLQSKNRKLAEMLDQRQAIEDELREHIEKLERRQATDDASLLIVNRYWSQFDENIRIILKRYDLDQG--LGDLLTERKALVVPEPEPDSDSNQERKDDRERGEGQEPAFSFLATLAS---SSSEEMESQLQ-ERVESSRRAVSQIVTVYDKLQEKVDLLSRKLNSGDNLIMEEAVQELNSFLAQENVRLQELTDLLQEKHHTMSQEFCKLQGKVETAESRVSVLESMIDDLQWDIDKIRKREQRLNRHLAEVLERVNSKGYKVYG------------AGSSLYGGTITINARKFEEMNAELEENKELAQNRHCELEKLRQDFEEVTTQNEKLKVELRSAVEEVVKETPEYRCMQSQFSVLYNESLQLKAHLDEARTLLHGTRGTHQRQVELIERDEVSLHKKLRTEVIQLEDT-LAQVRKEYEMLRIEFEQTLAANEQAGPINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLR--------SGSALLQSQSSTE-DAKDE-------------PTELKQDSEDLATHSSALKASQE--DEVKSKRDEEERERERREKEREREREREKE-KEREREKQK------LKESE---KERDPVKDKDKGKHDD----------GRKKEAEIIKQLKTELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKENKKMADEDALRKIRAVEEQIEYLQKKLAVAK-----------------------QEEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKLMSERIKSNQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEKEHLLQSNIGTGEKELGLRT-------QALEMNKRKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVTKEKDLFNFKRAQEDISRLRRKLETTKKP-DNVPK-----CDEILMEEIKDYKARLTCPCCNMRKKDAVLTKCFHVFCFECVKTRYDTRQRKCPKCNAAFGANDFHRIYIG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5DTM8-1", "uniprot_id": "BRE1A_MOUSE", "id": "Q5DTM8-1", "name": "E3 ubiquitin-protein ligase BRE1A", "aln": "MSGIGNKRAAGEPGTS-MPPEKKTAVED-------SG--TTVET-IKLGGVSSTEELDIRTLQSKNRKLAEMLDQRQAIEDELREHIEKLERRQATDDASLLIVNRYWSQFDENIRIILKRYDLDQG--LGDLLTERKALVVPEPEPDSDSNQERKDDRERGDGQEPAFSFLATLAS---SSSEEMESQLQ-ERVESSRRAVSQIVTVYDKLQEKVDLLSRKLNSGDNLIVEEAVQELNSFLAQENVRLQELTDLLQEKHHTMSQEFCKLQGKVETAESRVSVLESMIDDLQWDIDKIRKREQRLNRHLAEVLERVNSKGYKVYG------------AGSSLYGGTITINARKFEEMNAELEENKELAQNRHCELEKLRQDFEEVTTQNEKLKVELRSAVEEVVKETPEYRCMQSQFSVLYNESLQLKAHLDEARTLLHGTRGTHQRQVELIERDEVSLHKKLRTEVIQLEDT-LAQVRKEYEMLRIEFEQTLAANEQAGPINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLR--------SGSALLQSQSSTE-DPKDE-------------PTELKQDSEDLATHSSALKASQE--DEVKSKRDEEERERERREKEREREREREKE-KEREREKQK------LKESE---KERDSVKDKEKGKHDD----------GRKKEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKENKKMADEDALRKIRAVEEQIEYLQKKLAMAK-----------------------QEEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKLMSERIKSNQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEKEHLLQSNIGTGEKELGLRT-------QALEMNKRKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVTKEKDLFNFKRAQEDISRLRRKLETTKKP-DNVPK-----CDEILMEEIKDYKARLTCPCCNMRKKDAVLTKCFHVFCFECVKTRYDTRQRKCPKCNAAFGANDFHRIYIG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VTR2-1", "uniprot_id": "BRE1A_HUMAN", "id": "Q5VTR2-1", "name": "E3 ubiquitin-protein ligase BRE1A", "aln": "MSGIGNKRAAGEPGTS-MPPEKKAAVED-------SG--TTVET-IKLGGVSSTEELDIRTLQTKNRKLAEMLDQRQAIEDELREHIEKLERRQATDDASLLIVNRYWSQFDENIRIILKRYDLEQG--LGDLLTERKALVVPEPEPDSDSNQERKDDRERGEGQEPAFSFLATLAS---SSSEEMESQLQ-ERVESSRRAVSQIVTVYDKLQEKVELLSRKLNSGDNLIVEEAVQELNSFLAQENMRLQELTDLLQEKHRTMSQEFSKLQSKVETAESRVSVLESMIDDLQWDIDKIRKREQRLNRHLAEVLERVNSKGYKVYG------------AGSSLYGGTITINARKFEEMNAELEENKELAQNRLCELEKLRQDFEEVTTQNEKLKVELRSAVEQVVKETPEYRCMQSQFSVLYNESLQLKAHLDEARTLLHGTRGTHQHQVELIERDEVSLHKKLRTEVIQLEDT-LAQVRKEYEMLRIEFEQTLAANEQAGPINREMRHLISSLQNHNHQLKGEVLRYKRKLREAQSDLNKTRLR--------SGSALLQSQSSTE-DPKDE-------------PAELKPDSEDLSSQSSASKASQEDANEIKSKRDEEERERERREKEREREREREKE-KEREREKQK------LKESE---KERDSAKDKEKGKHDD----------GRKKEAEIIKQLKIELKKAQESQKEMKLLLDMYRSAPKEQRDKVQLMAAEKKSKAELEDLRQRLKDLEDKEKKENKKMADEDALRKIRAVEEQIEYLQKKLAMAK-----------------------QEEEALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKLMSERIKSNQIHKLLKEEKEELADQVLTLKTQVDAQLQVVRKLEEKEHLLQSNIGTGEKELGLRT-------QALEMNKRKAMEAAQLADDLKAQLELAQKKLHDFQDEIVENSVTKEKDMFNFKRAQEDISRLRRKLETTKKP-DNVPK-----CDEILMEEIKDYKARLTCPCCNMRKKDAVLTKCFHVFCFECVKTRYDTRQRKCPKCNAAFGANDFHRIYIG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R926-1", "uniprot_id": "F1R926_DANRE", "id": "F1R926-1", "name": "E3 ubiquitin protein ligase", "aln": "MSGQKRPSDAGSSATLGAPPEKKKGGEDGEGMSTGSGGSTAVETVIKLGGGANLEEQDIKALQIKNRKLGEALDQRQVIEDELRERVETLETRQATDDASLLILNRYWNQFDEHVRLFIRRCDQSGSEPVESQPPEGRSLKPGTPEPDGDSNQERAKD--RGQQGEGVSSFLATLAS---STSEEIDAELQ-ERVESSCKQASRVVEIYENLKNMVDQLKKDLESGKDGGLWDVAVRLNALLTGMNERLCQLTDGLQQKHSHMTSESRSLGRAANRADNRISELQGLIEELQWDMEKIRRRENRLNTHLVEVLERVNSKGYKVCG------------EASSVCG-TITINKRKFEEMNSELEENRELAENRLSELQKLQQDLQTVYQENTNMKVELLSRAEEVARDSAEYRCLQSQFSVLYNESLVLKSQLDETKARLNTTRTARLRQLDHMENDEVSLQRKVRTEVIQLEDT-LAQVRKEYEMLRIEFEQTLAANEQAGPINREMRHLISTLQTHNQQMKGEVVKYKLRLREAQQELNQLRAA--------KGNAAVQSQSSTEMDVKEETVSPLTPAPTTDVTVKTEPDSGSATPSTTGITVKTEPGTDAETVVKEEEKEKEK-DKEKEKEKDKEKEQRERERVTRG------STGSLGVKEERDKAGTSSSQSEDIPVERCAVIGGPKRKEMEQLKIVRVELKKAQESQREMKLLLDMYRSAPKEQRDKVQLMAAEKKTKSEAEELRQRVRELEERERREGKKMADEEALRKIRSVEEQIDILNKKLSLAK-----------------------QEEDALLSEMDVTGQAFEDMQEQNIRLMQQLREKDDANFKLMSERIKSNQIHKLLKEEKEELADQLLTLKTQVDAQLQVVRKLEEKERLLQGTISAAERELGLRT-------QALEMNKRKAQDSVLLSEEVRTQLEGVQQRLRSVREEVIENSISREKESFNARRAQEDISKLRRKIEKAKKPAENIRN-----GDEILNEEINEYKARLTCPCCNSRVKDAVLTKCFHVFCFECVKTRYDTRQRKCPKCNAAFGANDFHRIYIG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VRP9-1", "uniprot_id": "BRE1_DROME", "id": "Q9VRP9-1", "name": "E3 ubiquitin-protein ligase Bre1", "aln": "MSKRSADDATGSSCLVAAAAAGQPPIKK-----------VHFEP-HLIGPVSTLEEMDIKVLEFQNKKLAQRIEQRMRTEAELRHRIEQLEKRQTQDDAVLNVVNRYWNQLNEDIRVLLQRFDAETADELENRNENEVTTSFLAQLSTWDKEELDEKLANRVQVSKRAVAKIVQVIDRLMQRNEKITHVLKGDSLASAGSGSGAGAGGEEEQQQASGDAETTTSSAGVHALEETLKQTHIEIMSENHKLQNLNTSLHEKFHTMSLKMKEYQDAHTAKETENAELKNQIDELQYDLEKIHCRNDKLENHLAEAIEKLKAY-HQIYGDPNKSTNSAKTPTTTGSGGATTSVNSQLLEELQKELEEYRELANNRLQELDKLHATHRETLKEVEKLKMDIRQLPESVIVETTEYKCLQSQFSVLYNESMQIKTMLDETRNQLQTSKNQHLRQIEVMESEELIAQKKVRSEMIQMEDV-LALIRKEYETLRIEFEQNMAANEQTAPINREMRHLITSLQNHNGQLKGEVQRYKRKYKDTSTDNLKLRQELADALATLEGNKLQAATGAAGEEIKQE-------------NSTGVKEENSNNVSASGQTNQTNSGNDTNVAIKEENHISAEDEADDEASGKDVKDGIKQEKLSSGDAAAAEKKDSPGPGNSTSSATNSVPVKNEKDSKDGVKGKDVKAVESETVRDLKAQLKKALNDQKEMKLLLDMYKGVSKDQRDKVQLMATEKKLRSEIEELRQQLKKLQESKREERKKLADEEALRKIKQLEEQKYELQKQMANHKPTDNSWGSGAPGTANYTRPFVGSHEEEALLNEMEVTGQAFEDMQEQNSRLIQQLREKDDANFKLMSERIKANQLHKLLREEKTVLEDQMATATTQIEAMHIVLRKLEEKERSLQATVASIEKELMLRQ-------QAMEMHKRKAIESAQSAADLKLHLEKYHAQMKEAQQVVAEKTSSLEAEAYKTKRLQEELAQFKRKAERMKKMEMSGTT-----IDEVMIEEIREYKETLTCPSCKVKRKDAVLSKCFHVFCYDCLRTRYETRQRKCPKCNCAFGANDYHRLYLQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07457-1", "uniprot_id": "BRE1_YEAST", "id": "Q07457-1", "name": "E3 ubiquitin-protein ligase BRE1", "aln": "----------------------------------------------------MTAEPATKKIKLELSDPSEPLTQSDVIAFQKEALFRCINRR------------------RVDFEALRKQYELSRR------------------------------------------------------------------ECIDVSRKLANIMALIVTLARFIETFCTDAN--EKQLCREIAQGDETLIVQRSDSFMKLLTKYGKPNTTDSNTNSNASDHIQELTTELKNLRKSKEELFYENSQLTEEISALKEYYTNIIRKYDRDESFTIK---------------------RVFKEDKTDAVKELREDEKESNENNIKSGNKDSSAINGDNTSKKSEKGDELVQAEDERKEDAE------------NEKLELDLKFSDLRAEIN-SLSSTIKDLENIRRENEEELIKTRSEVSNLKKQQIAAADQDPDFKSYDHESLLAKIQHLTEQNAELSEINSSFLSKFQVLAKEKEIYTKKVREEFQKS------------------------------------------------------------------------------------------------------------------------------------------------------------LDSLVEMNSSLEKDVVR----------IRTARDDLLSKIAILEAEKSKTEVLSDLQHAIDILKEQWTKIDQRSNDTKSS--------------------------------------------STQDALIKEIQDLEKGFRELSDLTHKKYSEIINHESVISKLTVEKTKADQKYFAAMRSKDSILIEIKTLSKSLSKSNELILQLKDSDRLLQQKIGNLHKQLDLSQNNERRLIDSSKTETLKIIDLNNTSTKLKRSLEKLQEESNKSIADMTHLETKLNDTEIELKHFKQKASHLESKCEKLHDTLFRGNNKNKGSSDEALVEELANFRTLVYCSLCSKNWKNMAIKTCGHVFCENCCKERLAARMRKCPTCNKAFSSNDLLTVHL-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : :: : . .: : * : . .. :: * ... : :: : . . . . . : . : . : :* : : . .. *. ::* :: .:: . . *: : .: :.: . .: : :: *: :* :*. . :* . . . * : *. : .* **.: :. :.: : :: : :::: :. :: * *:*: :::. :* :: : :.*. :* :: * *: .: ::: .: : * *. : :: . : : :. .*:* : . .: .*: :: :**. .:*:: : *:: . :: * .: ::**:.*:: :.*.::.: . : .:: :::.. ** *: *::* : ..* : :: * ...:. :: :*::.:: ** .:. .::* * :: : .. * : : .:: ** : . .. : . . : : :: ::. :::. * * :. . ** : **: ::: : *. *. . *: .:..* **** :* : * :* ****.** **.:** ::: ", "identical_positions": 80, "similar_positions": 255, "identity": "7.39%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130405-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AWZ3-1", "uniprot_id": "A0A8I6AWZ3_RAT", "id": "A0A8I6AWZ3-1", "name": "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1", "aln": "MTLQQAGPGERSIGLLREADPLRAVGIHPSAWACPPPRSPPPPRSRDPQAPLGARPAVSARRPPPARPAPARISILNRRPPAPRPTAAGATTRAARNLGRGGGSRTAELCRKRPWDALRPGALDNEAAGAAARRGLCAPRPHLLARRVPCLSAHPAPHGSALRVRTPAVGPRGTRTGGLQGRCSRSLSAGLAARGGRGRRSPPARALHLASSAPEARVPAAGGAGCSRASEGGEAAAAPGDMYLLDGSGEPASSPADTMSRGMPPRKTVYRISVTMVRKEQLAAPAPRPTRRPRPARSPEAPGRLEEEAEEAAAEDPEIGPRAWDFRAFRTRSTGQLELGRLRPCAHDTEPTDLMGSPTTEGPSSPDGEEARAAPLRRSLSFRHWSEPEVPRSPALSGGRRHSSSGSLAWMPDDDVEAD--VVPEPVAGVQPAAEKRNTLDVGEVLSKNDALSDLERWERSKSKNRTLDNSDLQRLERARAAA--------AGPGAASEHRLLRFFSGIFARRDGGPSPRSGA-----LRSRGYFSLRRAPADTHSSSAESIEGSPRRDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPED-MDAGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSTNPRVIDDVRARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRK---------------KQQLSIGPCKSLPNS-------PSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTP--------STSQKELR----------IDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLAKDMSSLHISPNSGNVTSAS--GSQMASGISLVSFNSRPDGMHQRSYSVSSADQWSDATVIANSAISSDTGLGDSVCSSPSISSSTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLTGTAE-------------------------EQEENLEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCDTQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPMELIKVMSSIGNELANSVWEEGSQGRTKPSLDSTREEKERWIRAKYEQKLFLAPLP-----CTEFSLGQQLLHATAEEDLRTVILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLVQLLIWYGVDVMARDAHGNTALAYARQASSQE----------------------------------------CIDVLLQYGCPDERFVLMATPNLSRKNNSRNNSSGRAPSVI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BXK8-1", "uniprot_id": "AGAP1_MOUSE", "id": "Q8BXK8-1", "name": "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNYQQQLANSAAIRAEIQRFES--------VHPNIYSIYELLERVEEPVLQN------------------------------QIREHVIAIE-----DAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPE-----GGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSTNPRVIDDVRARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRK---------------KQQLSIGPCKSLPNS-------PSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTP--------STSQKELR----------IDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLAKDMSSLHISPNSGNVTSAS--GSQMASGISLVSFNSRPDGMHQRSYSVSSADQWSDATVIANSAISSDTGLGDSVCSSPSISSSTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAE-------------------------EQEENLEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCDTQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPMELIKVMSSIGNELANSVWEEGSQGRTKPSLDSTREEKERWIRAKYEQKLFLAPLP-----CTEFSLGQQLLRATAEEDLRTVILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVMARDAHGNTALAYARQASSQE----------------------------------------CIDVLLQYGCPDERFVLMATPNLSRKSNSRNNSSGRAPSVI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPQ3-1", "uniprot_id": "AGAP1_HUMAN", "id": "Q9UPQ3-1", "name": "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNYQQQLANSAAIRAEIQRFES--------VHPNIYSIYELLERVEEPVLQN------------------------------QIREHVIAIE-----DAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPE-----GGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRK---------------KQQLSIGPCKSLPNS-------PSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTP--------STSQKELR----------IDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLESRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPKTNGLSKDMSSLHISPNSGNVTSAS--GSQMASGISLVSFNSRPDGMHQRSYSVSSADQWSEATVIANSAISSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAE-------------------------EQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQKLFLAPLP-----CTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQE----------------------------------------CIDVLLQYGCPDERFVLMATPNLSRRNNNRNNSSGRVPTII-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B0C5-1", "uniprot_id": "A0A8M3B0C5_DANRE", "id": "A0A8M3B0C5-1", "name": "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1", "aln": "------------------------------------------------MYLLDGNYPERMERGTPQRKTVYRIS---------------LTLVKKENLQDGGGST------HRRLENPKVSAYRREGASEAQRS-----SQLEELKEVEDETDEFSAHSYMRNFRTFSTG---------------HLELGRLKLLKRAQHAHKERELNQTCILPENGQNKAIENGAPGEKRAEDVDES--DRLKRDAEHGKVCSTAAANGEKTGIRKKILKTSR--------STEEPVSTWPDEPCEEPKS-----------------------------VKTAKESCISSLLAKGNGKSPKPAPQTPPTKRHPS---------LLRRSFSFRHWTGGELIRIRALSKEKHHSSSGCIGRDGEGNQTQPGVVLQNMAFAETDSTEKRNTLDVGEVLNKTDSVTELGRRERMKGKNRTLDNSDLLRLSDKSLVDKEGFIRGMGSRSSGQERKLIRFFSGIFSKKDGTSTPLSSPSNRALRKNGLLGAQQRAEMGYSQSSSESVNGCPLDDAFVNSQEWTLSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEADVDAGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFALWVDAVIFVFSLEDEISFQTVYHYYSRMANYRNTAEVPLVLVGTQDAISAANPRVIDDTRARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKVVAIRK---------------KQQLSIGPCKSLPNS-------PSHSSVCAAPVSAVHISQNSNGGGSLSDYSSSVPSTP--------STSQKELR----------IDVPQTANTPTPVRKQSKRRSNLFTSRKGSEPDREKKGMDGRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRAISTCAAPS-PKTNGLTKDMSNMQLGQAPGSVTSSSS-ASQMASGISLVSFNSRPDGMHQRSYSVSSADQWSEATVIANSGISTDTGLGDSVCSSPSISSTTSPKMDPPPSPHANRKKHRRKKSTSNFKVDGFSGTAEAKHRAWKLNRVGSLRNIYNNSSNAEEQEDNFEFVIVSLTGQTWNFEATSYEERDAWVQAIESQILASLQSCESSKQKSRLSSQSEAIALQSVRNMRGNTRCVDCEAQNPDWASLNLGALICIECSGIHRNLGTHLSRVRSLDLDEWPLELIKVMSAIGNELANSVWEANAQGRLKPAPDASREERERWIRAKYEQKLFLASLT-----CTELSLGQQLLRATAEEDLRLVVILLAHGSRDEVNETCGEGDGRTALHLACRKGNVVITQLLVWYGVDIMARDAHSNTALAYARQANSQE----------------------------------------CMDVLLQYGCPDERYPLMATPNLSRRNNNRNNSCSSMNSAVI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NGC3-1", "uniprot_id": "CEG1A_DROME", "id": "Q9NGC3-1", "name": "Centaurin-gamma-1A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MSNYHPHSHPHALS----------------------------------HPHPQQVHNQLQNPHQNQLPPP-------------------------QRHNHAAPTAAASASGAP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSSASASASASILVAHPPQPLISNSLAIRQEIQRFES--------VHPSIYAIYELIDLLPMADAQIAQ----------------------------SIRDHVVCIE-----DSFVNSQEWTISRSVPDLRLGIVGSLNSGKSALVHRYLTGSYMQEESPE-----GGRFKKEVFIDGQSYLLLIRDEGGAPEMQFAGWVDAVIFVFSLENEGSFNTVYNYYTKMAHFRNGQEIPMILVGTQDAISERNPRVIDDTRARKLASDLKRCSYYETCATYGLNVERVFQDACQKILSQRLPLPPQVQPARPTTPQGNRLGLAPYQAPTNGQRGQQQLPLRMSADFAQAEQKLWSLQAASSSTINENNNITKYNPGAANSLQGDCSQVQLRDPRDLAPPPGKELPTPTSTPTTSRK-SRRRSNLFIPSSSKKADKEK---EPKSSELGSGRSIPIKQGYLYKRSSKSLNKEWKKKYVTLCDDGRLTYHPSLHDYMDDVHGKEIPLQYVTVKVPGQKPRGSKSIITNSALTSSLMANGQRAQNTLSDGIGCLTLAKDNQRKLSEKLSLLGAGSIAAGAGGEPLKSNSSQQTSGDEGIAMSNSNSQTFIAGEVANAGNKLEAQTPNVK---------KRHRRMKSSS-VKAN----EAD--------------------------DNDGYEFYIVSLDSKQWHFEAANSEERDEWVAAVEQEIFKSLQSIESSKTKQATSTDLAAMLAIRQR-VPGNGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLGSHISKVRSLGLDDWPSPHLSVMLAIGNSLANSVWESNTRQRVKPTSQASREDKERWVRSKYEAKEFLTPLGNGSSAHPSPSPGQQLIEAVIRADIKSIVSILANCPSEVTNANVSARDVRTPLLLACAIGNLAIAQLLIWNGANIKHTDHEGRTCLAYARAAQSLATAKSIKAAAAAQAGTTIPAPAPPTNGGIPAPQYNVEDTTALVELLEGLGCP-EAAPLTASGTLPRRRDTLGTPYEKSVSGVI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ** * . . .*: . : . .:: *:********:*****:*::****.* *************:*:****** *******:.:**************.** *** ************:* **:***:**::**::** *:*::********* *******.*****:.*****:******************..**::: * ::*.:.* :: .*. * : *. * .. * : ...::.: .. . .* . ** :** ::* .:.***. ** *:****** . .....*:** : ::..:****:****** * ***.****************:* ***********::****** * .******::* : * : : ..: : :. :. * :* :. :::. :**:. .* . * .. . .*::* * ** * .::* :...*..: . .: :*::. *:*** **:* .*.: *: :::. ** **** .: *:***:. **** ** *:*.:*: **** **** *. ::: *: * : ** **** : **:*******.*:******:*****:*:*:****.**:** :.** :***.******* .:: * **: :::**::***:*:*** * **:.* .. * **:*:.*. *:: : :**: . : .* . . * **.* *** **:.:.***:* *.:: * ...*.***** *.* :::* *** * * *: .*.*: :. ... : : ", "identical_positions": 388, "similar_positions": 240, "identity": "26.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130409-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K344-1", "uniprot_id": "PK3CA_RAT", "id": "A0A0G2K344-1", "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "aln": "MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFVIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPIDSFTMPSYSRRISTATPYMNGETATKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKG-AQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIKQHALN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P42337-1", "uniprot_id": "PK3CA_MOUSE", "id": "P42337-1", "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "aln": "MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLVTIKHELFREARKYPLHQLLQDETSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFVIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPIDSFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHTGLSNRLARDNELRENDKEQLRALCTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRSFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRQPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKG-AQEYTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFTKQMNDAHHGGWTTKMDWIFHTIKQHALN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42336-1", "uniprot_id": "PK3CA_HUMAN", "id": "P42336-1", "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "aln": "MPPRPSSGELWGIHLMPPRILVECLLPNGMIVTLECLREATLITIKHELFKEARKYPLHQLLQDESSYIFVSVTQEAEREEFFDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDMVKDPEVQDFRRNILNVCKEAVDLRDLNSPHSRAMYVYPPNVESSPELPKHIYNKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSSEQLKLCVLEYQGKYILKVCGCDEYFLEKYPLSQYKYIRSCIMLGRMPNLMLMAKESLYSQLPMDCFTMPSYSRRISTATPYMNGETSTKSLWVINSALRIKILCATYVNVNIRDIDKIYVRTGIYHGGEPLCDNVNTQRVPCSNPRWNEWLNYDIYIPDLPRAARLCLSICSVKGRKGAKEEHCPLAWGNINLFDYTDTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDWFSSVVKFPDMSVIEEHANWSVSREAGFSYSHAGLSNRLARDNELRENDKEQLKAISTRDPLSEITEQEKDFLWSHRHYCVTIPEILPKLLLSVKWNSRDEVAQMYCLVKDWPPIKPEQAMELLDCNYPDPMVRGFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNLLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLNRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDFMDALQGFLSPLNPAHQLGNLRLEECRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRNSHTIMQIQCKGGLKGALQFNSHTLHQWLKDKNKGEIYDAAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKG-AQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALEYFMKQMNDAHHGGWTTKMDWIFHTIKQHALN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QAD7-1", "uniprot_id": "F1QAD7_DANRE", "id": "F1QAD7-1", "name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "aln": "MPPRPSSGELWGIHLMPPRILVDCLLPNGMILTLECLREATLITIKHELFKEARKYPLHHLLQEETSYIFVSVTQEAEREEFYDETRRLCDLRLFQPFLKVIEPVGNREEKILNREIGFAIGMPVCEFDLVKDPEVQDFRRNILNVCKDSVELRDASGAHSRALYVYPPNVESSPELPKHIYGKLDKGQIIVVIWVIVSPNNDKQKYTLKINHDCVPEQVIAEAIRKKTRSMLLSAEQLKMCVQEYQGKYILKVCGCDEYLLEKYPISQYKYVRSCIMLGRLPNLMLMSKDSLYSQLPMDNFTMPSYSRRISTATPYMNGEASTKSLWTINSTLRIRVLCATYVNVNIRDIDKIYVRTGIYHGGEQLCDNVNTQRVPCSNPRWNEWLTYDMYIPDIPRAARLCLSICSVKGRKGAKEEHCPLAWGNVNLFDYTHTLVSGKMALNLWPVPHGLEDLLNPIGVTGSNPNKETPCLELEFDYFSSPVKFPDMATIEDHANWIISREMGYNYCQSGQSSRVARDHAMTEADIEQLRQLGNRDPLSEITEQEKDFLWRHRQYCVNIPEILPKILLAVKWNSRDEVAQMYCLLKDWPAIKPEQAMELLDCNYPDPMIRDFAVRCLEKYLTDDKLSQYLIQLVQVLKYEQYLDNPLVRFLLKKALTNQRIGHFFFWHLKSEMHNKTVSQRFGLLLESYCRACGMYLKHLSRQVEAMEKLINLTDILKQEKKDETQKVQMKFLVEQMRRPDYMDALQNFTSPLNPAHQLGNLRLEDCRIMSSAKRPLWLNWENPDIMSELLFQNNEIIFKNGDDLRQDMLTLQIIRIMENIWQNQGLDLRMLPYGCLSIGDCVGLIEVVRSSHTIMQIQCKGGLKGALQFNSTTLHQWLKDKNKGEMYDMAIDLFTRSCAGYCVATFILGIGDRHNSNIMVKDDGQLFHIDFGHFLDHKKKKFGYKRERVPFVLTQDFLIVISKGGTQECTKTREFERFQEMCYKAYLAIRQHANLFINLFSMMLGSGMPELQSFDDIAYIRKTLALDKTEQEALDYFMKQMNDAHHGGWTTKMDWIFHTIRHHAQN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********************:********:**********:*******:********:***:*:****************:************************************.*********:******************::*:*** ...****:******************.****************************************************:****:** ****************:*****:*****:********:******:*:*******:* ********************::*****.***:***::*************************** *********************.**:****:******************************:******.********************************************:*** ******:.**:**** :*** *:.*.::* *.*:***: : * * ***: : .**************** **:***.*******:**:***************:****.******************:*.********************************** ******************************************************.*************************************:**:*****.* ***************:************************************************************************************.********************* *************:** *************************************************************************** :** *****************************************************************:** **********************::** *", "identical_positions": 972, "similar_positions": 74, "identity": "90.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130411-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O75995-1", "uniprot_id": "SASH3_HUMAN", "id": "O75995-1", "name": "SAM and SH3 domain-containing protein 3", "aln": "MLRRKPSNASEKEPTQK-KKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVPTPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMADTLEEGSASPTSP-DYSLDSPGPEKMALAFSEQEEHELPVLSRQASTGSELCSPSPG-SGSFGEEPPAPQYTGPFCGRARVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGHARPSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDPQHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAHTVSEPKVDIPRDSGCFEGSESGRD---DAELAGTEEQLQGLSLAGAP-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K352-1", "uniprot_id": "SASH3_MOUSE", "id": "Q8K352-1", "name": "SAM and SH3 domain-containing protein 3", "aln": "MLRRKPSNASDKEPTQK-KKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVLTPEDSGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMGDTLEEGSASPTSP-DCSLDSPGPEKMALAFTEQEEREPPSLSRQTSTGSELCSPGPG-SGSFLEESPAPQYTGPFCGRARVHTDFTPSPYDHDSLKLQKGDVIQIVEKPPVGTWLGLLNGKLGSFKFIYVDVLPEEAVGPVRPSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDPQHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAHTVSEPKVDIPRDSGCFEGSESGRD---EAELAGTEEQLQGLSLSGAP-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7EZR2-1", "uniprot_id": "E7EZR2_DANRE", "id": "E7EZR2-1", "name": "", "aln": "MLRRKPSNASEKEQSQAQKKKPLQRSASFKDFMKSKPSSPVTNP-EPLLNESLFEAAP----PEESGKSHGKLGKKWRNVITRTMTRKTSKMVQKALAEEGNESGEDGSMSPMSPTDWTPDLTAGNRTSVCSNSSEDTIHSPLSRQLSGCADRQSLDSGFSQRDSMRLEDSTYMGPFCGRAVVITDFTPSPYDIDCLKLQKGDIIQIIEKPPVGTWTGKLNNKVGSFKFVYVSMLPEEETPPKRKRSHSHGHQKAKPKTLEEVLERIGLTELGSLLSMHGFQSLEDFTGLKESHLNDLNITDPEQRVKILKATELIHDSEDESDAEEQKTEMPRDSGCYESTENLANEREEPQVDSQAEPETDPDTEIKLNAVQEQLEVMKVEESPETQTE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********:** :* ** .****:***** ********.. * *::.: * . **::*** ******* **:***.** .**: ***:** :: *:** ** ** * : * .. :: ::. ...*: . **** * :: * ..* * . . * ******* * ********* *.*******:***:******** * **.*:*****:**.:**** . * :. ::.*****.*:****** * * * ::*:*:****. *:*:***:*** **::*.*:*.*:**: * : *: *: :* .::. .: :* .: .:. . :*. * : :* ..:***: :.: :* ", "identical_positions": 181, "similar_positions": 100, "identity": "46.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130411-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JMA9-1", "uniprot_id": "S6A14_MOUSE", "id": "Q9JMA9-1", "name": "Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)", "aln": "-----MDRLKCPNFFKCRQKEK-VTASSENFHVGENDENQERGNWSKKSDYLLSMVGYAVGLGNVWRFPYLTYTNGGGAFLIPYAIMLALAGLPLFFLECSLGQFASLGPVSVWRILPLFQGVGITMVLISVFVAIYYNVIIAYSLYYLFASFQSVLPWANCSSWADENCSRTPIVTGCNVSIG----AGEMFMNISWVNTNNLTCLNGSEVFRPGQLPSEQYWDKVTLQRSSGMDETGVVVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFPYVVLLILLIRGATLEGASKGISYYIGAQSNFTKLREAEVWKDAATQIFYSLSVAWGGLVALSSYNKFNNNCYSDAIIVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDLAFIAYPEALAQLPAGPFWSILFFFMLLTLGLDSQFASIETITTTFQDLFPKAMKRMRVPITLGCCLILFLLGLLCVTQAGIYWVHLIDHFCAGWGILIAAILEIAGIIWIYGGNRFIEDIEMMIGAKRWIFWLWWRACWFVITPILLSAILVWSLVKFHRPDYADIPYPDWGVALGWCMIIFCIIWIPIMAIIKIVQAEGNILQRIISCCRPASNWGPYLEKHRGERYRDMAEPAKETDHEIPTISGSTKPE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UN76-1", "uniprot_id": "S6A14_HUMAN", "id": "Q9UN76-1", "name": "Sodium- and chloride-dependent neutral and basic amino acid transporter B(0+)", "aln": "-----MDKLKCPSFFKCREKEK-VSASSENFHVGENDENQDRGNWSKKSDYLLSMIGYAVGLGNVWRFPYLTYSNGGGAFLIPYAIMLALAGLPLFFLECSLGQFASLGPVSVWRILPLFQGVGITMVLISIFVTIYYNVIIAYSLYYMFASFQSELPWKNCSSWSDKNCSRSPIVTHCNVSTVNKGIQEIIQMNKSWVDINNFTCINGSEIYQPGQLPSEQYWNKVALQRSSGMNETGVIVWYLALCLLLAWLIVGAALFKGIKSSGKVVYFTALFPYVVLLILLVRGATLEGASKGISYYIGAQSNFTKLKEAEVWKDAATQIFYSLSVAWGGLVALSSYNKFKNNCFSDAIVVCLTNCLTSVFAGFAIFSILGHMAHISGKEVSQVVKSGFDLAFIAYPEALAQLPGGPFWSILFFFMLLTLGLDSQFASIETITTTIQDLFPKVMKKMRVPITLGCCLVLFLLGLVCVTQAGIYWVHLIDHFCAGWGILIAAILELVGIIWIYGGNRFIEDTEMMIGAKRWIFWLWWRACWFVITPILLIAIFIWSLVQFHRPNYGAIPYPDWGVALGWCMIVFCIIWIPIMAIIKIIQAKGNIFQRLISCCRPASNWGPYLEQHRGERYKDMVDPKKEADHEIPTVSGSRKPE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6NN04-1", "uniprot_id": "F6NN04_DANRE", "id": "F6NN04-1", "name": "Transporter", "aln": "MKDYSLKNIRGVLFKNSVGDEQDKDKSDKAEHVVQNDENSDRGNWSSKREYMLSMIGYAVGLGNVWRFPYLAYKHGGGAFLIPYTIMLAVSGLPLFFMESSFGQFCSQGPINVWKAVPILQGVGITMMLVSTFVAIYYNVIIAYSIYYLFASFQDPLPWS------IKNCN----TTASNISTA--------AVNVSCGQIS-------------GQSLSEKYWDEVALQRSSSMDETGPVVWHLALCLLLSWILVGAALFKGIKSSGKVVYFTATFPYIVLLILLIRGATLEGAKDGIEFYIGSQSNLTKLAEAEVWKDAATQIFFSLSIAWGGLMALSSYNKFYNNCYQDSIVVCVTNCGTSIFAGFAIFSVLGHMAHVYQRPVSEVADAGFALAFIAYPDALSKLPISPLWSILFFFMLITLGLDSQFAGIEVISTCLLDAYPEVLKSKRGLVTTAVCIILFLLGLPCVTRAGIYWVNLIDTFSAGWILLVAGLLEVLGLCILYGGNRFIKDIEMMIGTKSSLFWLWWRACWFFITPVVLSIILIWSLYTFTSPTYSSVAYPDWGISLGWCITAFSLMWIPIVAVWKVCKARGGLWQRIKSACSPTEDWGPYLECHRGERYG----TRGETDPNIFVISNKVSTRL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..:: * :. .*: *.: ** :****.:*****.* :*:***:***************:*.:*********:****::******:*.*:***.* **:.**: :*::*******:*:* **:**********:**:*****. *** :**. .* .*:* :* * : . ** **:**::*:*****.*:*** :**:*******:*::******************** ***:******:********..**.:***:***:*** *************:***:*****:******** ***:.*:*:**:*** **:********:******: : **:*..:** *******:**::** .*:*********:*********.**.*:* : * :*:.:* * :* . *::****** ***:******:*** *.*** :*:*.:**: *: :*******:* *****:* :**********.***::* *::*** * * *. :.*****::****: *.::****:*: *: :*.*.: **: *.* *:.:****** ****** . *:* :* .:*.. ... ", "identical_positions": 378, "similar_positions": 150, "identity": "58.24%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130412-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZUV5-1", "uniprot_id": "A0A8I5ZUV5_RAT", "id": "A0A8I5ZUV5-1", "name": "", "aln": "MASVFMCGVEDLLFSGSRFVWNLTVSTLRRWYTERLRACH-------------QMTEGRHCQVHLLDDRRLELLVQPKLLSRELLDLVASHFNLKEKEYFGITFIDDTGQENWLQLDHRVLEHDLPKKPGPAVLHFAVRFYIESISFLKDKNTVELFFLNAKACVHKGQIEVDSETIFKLAALVLQESKGDYTSDENARKDLKTLPVFPTKTLQEHPSLAYCEDRVIEHYLKIKGLTRGQAVVQYMKIVEALPTYGVHYYAVKDKQGLPWWLGISYKGIGQYDLQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTWYANSSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDDIAMDLTETGTQRVSKLVTLEAKSQFIMASNGSLISSGSQDSEGMEEQKREKILELKKKEKLLQEKLLKKVEELKKICLREAELTGRMPKEYPLNIGEKPPQVRRRVGTTFKLDDNLLPTEEDPALQELESNFLIQQKLVEAAKKLASEPDLCKTVKKKRKQDYTDAVKRLQEIENSINEYRIRCGKKPSQKAAVVPPEDIIPSESSSLSDTTTYDD--PNDSFTLAGQRPSSVPHSPRILPPKSLGIERIHFRKSSINEQFVDTRQSRE--------MLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPDSSSQHCRQRSGSLESQSHLLSEMDSDKPFFTLSKSQRSSSTEILDDGSSYTSQSSSEYYCVTPAAGPYYTTQTLDTRARGRRRSKKHSVSTSNSGSMPNLAQKDTLRNGVYSKGQDPPPS-GYYIAGYPPYAECDLYYSGGYVYENDTEGQYSVNPSYQSSAHYGYDRQRDYSRSFHEDEVDRVPHNPYATLRLPR-KAAVKSEHITKNIHKAIVAEHLRGWYQRASGQKDQGHSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTNASGNWRTQLTTGLSEYENPVHSPYTSYYGNIYN--PLPSPNR-----------QYAESTPLDGTDGNQLEDSLESSEQRLFWHED-----SKPGTLV----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q920B0-1", "uniprot_id": "FRM4B_MOUSE", "id": "Q920B0-1", "name": "FERM domain-containing protein 4B", "aln": "MASVFMCGVEDLLFSGSRFVWNLTVSTLRRWYTERLRACHQVLRTWCGLRDVYQMTEGRHCQVHLLDDRRLELLVQPKLLSRELLDLVASHFNLKEKEYFGITFIDDTGQENWLQLDHRVLEHDLPKKPGPTLLHFAVRFYIESISFLKDKNTVELFFLNAKACVHKGQIEVDSETIFKLAALVLQESKGDYTSDENARKDLKTLPVFPTKTLQEHPSLAYCEDRVIEHYLKIKGLTRGQAVVQYMKIVEALPTYGVHYYAVKDKQGLPWWLGISYKGIGQYDLQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTWYANSSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDDIAMDLTETGTQRGSKLVTLEAKSQFIMASNGSLISSGSQDSEGMEEQKREKILELKKKEKLLQEKLLQKVEELKKICLREAELTGRMPKEYPLNIGEKPPQVRRRVGTTFKLDDNLLPTEEDPALQELESNFLIQQKLVEAAKKLASEPDLCKTVKKKRKQDYTDAVKRLQEIENSINEYRIRCGKKPSQKAAVVPPEDIIPSESSSLSDTTTYDD--PNDSFTLAGQRPSSVPHSPRILPPKSLGIERIHFRKSSINEQFMDTRHSRE--------MLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPDSSSQHCRQRSGSLESQSHLLSEMDSDKPFFTLSKSQRSSSTEILDDGSSYTSQSSSEYYCVTPAASPYYTTQTLDTRARGRRRSKKHSVSTSNSGSMPNLAQKDPLRNGVYSKGQDPPPS-GYYIAGYPPYAECDLYYSGGYVYENDTEGQYSVNPSYRSSAHYGYDRQRDYSRSFHEDEVDRVPHNPYATLRLPR-KAAVKSEHITKNIHKALVAEHLRGWYQRASGQKDQGHSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTNASGNWRTQLTIGLSEYENPVHSPYTSYYGSIYN--PLSSPSR-----------QYAETTPLDGTDGSQLEDNLEGSEQRLFWHED-----SKPGTLV----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2L6-1", "uniprot_id": "FRM4B_HUMAN", "id": "Q9Y2L6-1", "name": "FERM domain-containing protein 4B", "aln": "MASVFMCGVEDLLFSGSRFVWNLTVSTLRRWYTERLRACHQVLRTWCGLQDVYQMTEGRHCQVHLLDDRRLELLVQPKLLARELLDLVASHFNLKEKEYFGITFIDDTGQQNWLQLDHRVLDHDLPKKPGPTILHFAVRFYIESISFLKDKTTVELFFLNAKACVHKGQIEVESETIFKLAAFILQEAKGDYTSDENARKDLKTLPAFPTKTLQEHPSLAYCEDRVIEHYLKIKGLTRGQAVVQYMKIVEALPTYGVHYYAVKDKQGLPWWLGISYKGIGQYDIQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTWYANSSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDEIAMDLTETGTQRASKLVTLETKSQFIMASNGSLISSGSQDSEVSEEQKREKILELKKKEKLLQEKLLKKVEELKKICLREAELTGKMPKEYPLNIGEKPPQVRRRVGTAFKLDDNLLPSEEDPALQELESNFLIQQKLVEAAKKLANEPDLCKTVKKKRKQDYTDAMKKLQEIENAINEYRIRCGKKPSQKATVLP-EDIIPSESSSLSDTTTYDD--PSDAFTFPGQRSSSVPHSPRILPPKSLGIERIHFRKSSINEQFVDTRQSRE--------MLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPESSSQHCRQRSGSLESQSHLLSEMDSDKPFFSLSKSQRSSSTEILDDGSSYTSQSSTEYYCVTPVTGPYYTTQTLDTRTRGRRRSKKQNVSTSNSGSMPNLAQKDSLRNGVYSKSQEPPSS-SYYIAGYTPYAECDFYYSGGYVYENDTEGQYSVNPSYRSSAHYGYERQRDYSRSFHEDEVDRVPHNPYATLRLPR-KAAAKSEHITKNIHKALVAEHLRGWYQRASGQKDQGHSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTNASGNWRTQLTIGLSDYETPAHSSYTSCYGNVYN--PLPSPSR-----------QYTEISQLDGTDGNQLEDNLESSEQRLFWHED-----SKPGTLV----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PN59-1", "uniprot_id": "A0A8M9PN59_DANRE", "id": "A0A8M9PN59-1", "name": "", "aln": "MALGLFCCMEDLLAAGSQLVWTVAEQVLRRCYSDGLVPCRRFLQTWCLLGDVYQMTEGRLCQVLLLDDRQLELLVQPKLLSRDLLDLVSSHFNLKEKDYFGISFTDERGQKKWLQLDRRVLDHDFNKKSGPLELKFQVRFYIESVAYLKDATTVELFFRNAKISVYNENIEVESEIVFKLAAYTLQEANGDYTSDESTRSALKKLPAFPTAVLKEHPSLTFCEDKVIERYKKLKGLSRGQAIVRYLTLVESLPAYGVHYYKVKDKQGLPWWLGISYKGIGQYDLQDKLKPRKLFLWKQLENLYFREKKFAVEVNDPQRRTASRRTFGQSGQAIHTWYASHSLIKTIWVMAISQHQFYLDRKQSKAKITTARSLGDIAMDLTETGAPRNSKLVSMESKDKLIMASNGSLVSSNSADNDVNEEQKKEKIAELKDKQEKIKQILALKEEELKKMCLREAELTGVLPKEFPLASGEKPPTIRRRVGTAFKLDD-LFPYDADPCLRNLESCFALQKKIVEAARKLAHENELGKTVKKKRRRNLLDATKKLQAIENEINDYRVKIGKEPTQRASVIIADDVN---LDSLSDCLNLDDDEPSQRQRSRSVQYSPLPNSSGSFTASYHSDQLDHANDDYSNCSRLNYAEVQEPVAYIHEDALSTHSSPYRQPLRQPSDSRSMPPTPQLPRNAYSSIQL-----STLYRQRSGSLESQSQFLTESEPSEPVF-ISAPRRSNSTELLDDGSSYTSQSSVEYSAP-------------HSRAKNRHRRRQGNIY-ANTGSMPNLAQNDTR--GYISQSQHPQTTTAYYVTGYPRYIEPEVYPNGPYMYESEMEGHYNVNPSYHRHEPHGN---------YAQDEMDGLSHNLYATLRPPRNRPPSRNDNLVKNMQRAEVVEHLRGWYNRQ-------HKPQ-GYDAYRAPQQSLNYRTMSTSYVRSDSTASYSTVG----SGNWHGQPVMAMSEYEMPLAHHQSYGYNTVHHSHPLHSSSHPKRAWHCPASPQYYHPRFSQACSSSLPPRPLPPSSSCYQMKQTGLSAPQTGGARVNKASFAKCSP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ::* :**** :**::**.:: ..*** *:: * .*: ****** *** *****:**********:*:*****:********:****:* *: **::*****:***:**: **.** *:* *******:::*** .****** *** .*:: :***:** :***** ***::*******.:*. **.**.*** .*:*****::***:***:* *:***:****:*:*:.:**:**:****** **********************:***:****** ******************:**:* :.********* ::****. ****:**********************.:****.:*********: * ****::*:*.::********:**.* *.: ****:*** ***.*:: ::: * * *****:********* :***:** ***** :******:***** *:* : **.*::*** * :*:*:****:*** * :* *******::: ** *:** *** **:**:: **:*:*:*:*: :*: .**** . ** *.: . : *.:*:*. :... . : * ... * . :: . :* ********: *:*...****.** *.****** :* * ***********::*:* :..:*.* :* .:**.***:************ ** . .:*::.*:* :: .: :*:********:*. * *:.*.* .: .**::**. * * :.* .* *:**.: **:*.*****: :* : :**:* :.** ***** ** :.. :.:::.**:::* *.*******:* *.** .:*: *..*:.*.: :... *. ::***:*. ****: * . .:*:** * : *..::: ** *..: ** . :. ... * *.. :: .. *: * ", "identical_positions": 542, "similar_positions": 266, "identity": "50.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130415-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TBC3-1", "uniprot_id": "SHKB1_HUMAN", "id": "Q8TBC3-1", "name": "SH3KBP1-binding protein 1", "aln": "MAAAATAAEGVPSRGPPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNFLRTKELDPRGVHGSSLLHEAQFYGLTPLVRRLQLREELDRSSCGNVLFNGYLPPPVFPVKRRNRHSLVGPQQLGGRP-----APVRRSNTMPPNLGNAGLLGRMLDEKTPPSPSGQPEEPGMVRLVCGHHNWIAVAYTQFLVCYRLKEASGWQLVFSSPRLDWPIERLALTARVHGGALGEHDKMVAAATGSEILLWALQAEGGGSEIGVFHLGVPVEALFFVGNQLIATSHTGRIGVWNAVTKHWQVQEVQPITSYDAAGSFLLLGCNNGSIYYVDVQKFPLRMKDNDLLVSELYRDPAEDGVTALSVYLTPKTSDSGNWIEIAYGTSSGGVRVIVQHPETVGSGPQLFQTFTVHRSPVTKIMLSEKHLISVCADNNHVRTWSVTRFRGMISTQPGSTPLASFKILALESADGHGGCSAGNDIGPYGERDDQQVFIQKVVPSASQLFVRLSSTGQRVCSVRSVDGSPTTAFTVLECEGSRRLGSRPRRYLLTGQANGSLAMWDLTTAMDGLGQA---PAGGLTEQELMEQLEHCELAP------------------------------------PAPSAPSWGCLPSPSPRISLTS------LHSASSNTSLSGHRGSPSPPQAEARRRGG---------GSFVERCQELVRS--------------------------GPDLRRP-----------------------------------PTP------------------------------APWPSSGLGTPLTPPKMKLNETSF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P7W2-1", "uniprot_id": "SHKB1_MOUSE", "id": "Q6P7W2-1", "name": "SH3KBP1-binding protein 1", "aln": "MAVATTAVEGVPSRGAPGEVIHLNVGGKRFSTSRQTLTWIPDSFFSSLLSGRISTLKDETGAIFIDRDPTVFAPILNFLRTKELDPRGVHGSSLLHEAQFYGLTPLVRRLQVREELDRSSCGNVLFNGYLPPPVFPVKRRNRHSLVGPQQIGGRP-----APVRRSNTMPPNLGNAGLLGRMLDERAPPSPSGQPEEPGMVRLVCGHHNWIAVAYTHFLVCYRLKEASGWQLAFSSPRLDWPIERLALAARVLGGAPGEHDKMVAAATGSEILLWALQAQGGGSEIGVFHLGVPVEALFFVGNQLIATSHTGRIGVWNAVTKHWQVQEVQPITSYDAAGSFLLLGCSNGSIYYVDVQKFPLRMKDNDLLVSELYRDPAEDGVTALSVYLTPKTSDSGNWIEIAYGTSSGVVRVIVQHPETVGSGPQLFQTFSVHRSPVTKIMLSEKHLISVCADNNHVRTWSVTRFRGMISTQPGSTPLASFKILALESVDGLGGCSAGNDIGPYGERDDQQVFIQKVVPNASQLFVRLSSTGQRVCSVRSVDGSPTTAFTVLECEGSRRLGSRPRRYLLTGQANGSLAMWDLTTAMDGLGQT---PAGGLTEEELMDQLEQCELSP------------------------------------LASSR---GSFPSPSPRTSLTS------LHSASSNTSLYGPRGSPSPPQAEARRRGA---------GSFVDRCQELARG--------------------------APELRWP-----------------------------------PTP------------------------------APRPSTSLGNPLTALKKTLNETSF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FFI2-1", "uniprot_id": "E7FFI2_DANRE", "id": "E7FFI2-1", "name": "BTB/POZ domain-containing protein KCTD3", "aln": "-------------MARIGDIIHLNVGGKRFSTSRQTLTWVPDSFFSSLLSGRISTLKDETGAIFIDRDPSLFAPILNFLRTKELHPRSIDVHLLIHEAEFYGITPLVRKLQLCDELDRSSCGNVLFNGYLPPPVYPVKRRNRHSVAGPQFMGGRSGPVERAPVRRSNTMPPNLGNAGILGRAAVEERVPGPVS---DPGLVRIICGHHNWIAVAYAQFVVCYRVKESTGWQQVFTSPRLDWVIDRVALNAKVMGGSLGDNDKMVAVASGTEIILWAICPDGNGNEIGVFSLNVPVEALFFVGNQLIATSHTGKVGVWNAVTKHWQNQDVVPINSYDTAGSFLILGCNNGSIYYIDVQKFPLRMKDNDLLVTELYRDPSEDAITALSVYLTPKTSDSGNWIEIAYGTSSGTVRVIVQHPETVGSGPQLFQTFSVHRSPVTKIMLSEKHLISVCADNNHVRTWTVTRFRGMISTQPGSTPLTSFKILSLDDIDGHAGCAAGTEIGPYGERDEQQVFIQRVVPDTDKLYVRLSSNGKRVCEVRSVDGTSITAFVVHECEGSSRIGSRPRRYLFSGHSNGSIQMWDLTTAMEIAGKVDIKALGGPTEEELLELLDQCDLTLTRTPDMSPAASLTHSSRNSTCSLQSQMSESSRAASGFRSAVPLSGSLPRQPPLVPLTNKPRDLPSHLGLSQSSIPSSSGSSPHPGREKERDALRDGLLSIRRGSFVERCQERAKCSDATAGLDPSRRSLAVCNELEARLGLSSSLRMPSSFSALPAGCLSPPSSSSSSLSSASVRRAAPAPVSPAPPSLSPTRSQTPASARRPISSPTNDSPANDSTPAPESPASPPATSPKPHMNETSF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *::*******************:*****************************::*************.**.:. *:***:***:*****:**: :********************:*********:.*** :***. *****************:*** *. *.* . :**:**::***********::*:****:**::*** .*:****** *:*:** *:* **: *::*****.*:*:**:***: .:*.*.***** *.********************::*********** *:* **.***:*****:***.******:****************:******:**.:*************************** *********************:*****************************:*****************:*****:*:. ** .**:**.:********:******:***.:.:*:*****.*:***.******:. ***.* ***** *:********::*::***: ********: *:. . ** **:**:: *::*:*: .: *.:* .* .**. * . *::*: . **.. * * .* . ****:**** .: ...** * *:* :* *.: . * *. * :*****", "identical_positions": 488, "similar_positions": 134, "identity": "56.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130415-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80XA6-1", "uniprot_id": "REPS2_MOUSE", "id": "Q80XA6-1", "name": "RalBP1-associated Eps domain-containing protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MEVAAGGGCGAG-PPLLLSDSEQQCYSELFARCAGAASGGPGPGPPEATR-------------------------------------------------------------------VAPGTATAAAGPVADLFRASQLPPETLHQITELCGAKRVGYFGPTQFYVALKLIAAAQAG--LPVRTESIKC-------------------------ELPLPRFVMS--KNDGEIRFGN--------PAELHGPKVQIPYLTTEKNSFKRMDN-EDKQ-ETQSPTMSPLAS---PPSSPPHYQRVSLSHGYSKLRSGTEQMHPAPYE--RQPIG---------------------------------------QPEGPSSEGPGAKPFRRQASLIRSFSVEREPQENNSNYPDE-----------------PWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLSEFCAAFHLIVARKNG--YPLPEGLPPTLQP-----------------------------------EYLQAAFPKSKWECAIFDS--YSESMPANQQSCDLNRMEKTSVKDVADFPVPTQDVTTADDKQALKSTVNESLPKDVS-------------------------------------------------------------------------EDTATSKDYNSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASS-----------------------------------------------------LDLNKVFLPSAPAANSGLLPPPPALPPRPCPTQ-----------SEPVSE----ADLHSQLN----------RAPSQAAESSPTKMDAPHAQP---PSKPIRR-KFRPENQTTESQEPAAAVGGAVSAAMVKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AED1-1", "uniprot_id": "A0A8I6AED1_RAT", "id": "A0A8I6AED1-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MEVAAGGGGGAG-PPLLLSDSEQQCYSELFARCAGAASGGPGPGPLEATR-------------------------------------------------------------------VAPGILTAAAGPVADLFRASQLPPETLHQITELCGAKRVGYFGPTQFYVALKLIAAAQAG--LPVRTESIKC-------------------------ELPLPRFVMS--KNDAEMRVGN--------PAELHGTKVQIPYLTSEKNSFKRLDD-EEKQQETPSPRMSPLAS---PPSSPPHYQRVPLSHGYSKLRSGTEQMHPAPYES-RQPIG---------------------------------------QPEGPSSEGPGTKPFRRQASLIRSFSVERELQENNSNYPDE-----------------PWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIAELSYIWELSDADCDGALTLPEFCAAFHLIVARKNG--YPLPEGLPPTLQP-----------------------------------EYLQAAFPKSKWECVIFDS--YSESMPANQQSCDLNRMEKTSVKDMADFPVSTQDVTTGDDKQALKSTVNESLPKDVS-------------------------------------------------------------------------EDTATSKDCNSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASS-----------------------------------------------------LDLNKVFQPSVSAANSGLLPPPPALPPRPCPTQ-----------AEPASE----ADLYPQMN----------RAPSQAAESSPTKKDVPHAQP---PSKPIRR-KFRPENQTTEGQESAAVVGGAAPAAMVKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NFH8-1", "uniprot_id": "REPS2_HUMAN", "id": "Q8NFH8-1", "name": "RalBP1-associated Eps domain-containing protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MEAAAAAAAAAAAAAAAGGGCGSGPPPLLLSEGEQQCYSELFARCAGAAGGGPGSGPPEAAR-------------------------------------------------------------------VAPGTATAAAGPVADLFRASQLPAETLHQITELCGAKRVGYFGPTQFYIALKLIAAAQSG--LPVRIESIKC-------------------------ELPLPRFMMS--KNDGEIRFGN--------PAELHGTKVQIPYLTTEKNSFKRMDD-EDKQQETQSPTMSPLAS---PPSSPPHYQRVPLSHGYSKLRSSAEQMHPAPYEA-RQPLV---------------------------------------QPEGSSSGGPGTKPLRHQASLIRSFSVERELQDN-SSYPDE-----------------PWRITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTKSKLSIPELSYIWELSDADCDGALTLPEFCAAFHLIVARKNG--YPLPEGLPPTLQP-----------------------------------EYLQAAFPKPKWDCQLFDS--YSESLPANQQPRDLNRMEKTSVKDMADLPVPNQDVTS-DDKQALKSTINEALPKDVS-------------------------------------------------------------------------EDPATPKDSNSLKARPRSRSYSSTSIEEAMKRGEDPPTPPPRPQKTHSRASS-----------------------------------------------------LDLNKVFQPSVPATKSGLLPPPPALPPRPCPSQ-----------SEQVSE----AELLPQLS----------RAPSQAAESSPAKKDVLYSQP---PSKPIRR-KFRPENQATENQEPSTAASGPASAATMKPHPTVQKQSSKQKKAIQTAIRKNKEANAVLARLNSELQQQLKEVHQERIALENQLEQLRPVTVL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B9B6-1", "uniprot_id": "A0A8M2B9B6_DANRE", "id": "A0A8M2B9B6-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MDPGSAGG-----TFMSLSDTEQRCYSGLYALCQPDSSGIP------------------------------------------------------------------------------------AAGKVAELFRASQLPAETLHQVMEVCGAKRLGFFGCGQFYAALKLLAAAQAG--LPVRLESIAG-------------------------ELPLPVFVGI--TNELDTRYANHLSTSESQPHTLGSVPASAPRPPTDRAVLRHPDTSMDKQEAWSPPRSPPSIS---PPRSPSAYR----SLTYSAQRNGTDTLLAYDGKMPGRPSV---------------------------------------PQENASPGHYSFKLQPEQPSITRVASVERLVERVEVDYSDD-----------------PWRITEEQREYYTNQFRSLQPDLNALIMGAVAKNFFTKSKLPIPELSHIWELSDVDKDGALTFPEFCTAFHLIVARKNG--YLLPETLPASLRPG-------------------------------FQEPVVTAAPSEATQPLIVFDDNMMPGANQLEIGSVDLQVTSRPGVTTKQDTRDESRKPEISPKRVPEPHEKPMQRVSALK-------------------------------------------------------------------------PDSPQELDAN-MKSRTRPRSYSSTSIDDAMKKVEEPPTPPPRPQKSHSRASS-----------------------------------------------------LDLNKLLQQGTPGAKSGWLPPPPALPPRPPATQIFSFLPGLEKSSQKAVQ----QPNFADFSRFREEQESGVRAGLSTEDLLPPKSDCSLVHQGHAPQKPMRR-KLHPESQSATPPLTTPYS----AATLTKPT---QRPPPKQKREIQMAIRKNRETNAVLTRLNSELQQQLKVVHGERLTLETQLESMRPVAST-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32521-1", "uniprot_id": "PAN1_YEAST", "id": "P32521-1", "name": "Actin cytoskeleton-regulatory complex protein PAN1", "aln": "MYNPYQQQGMGYQQQQQQQQQQPNGFYPQQQQGQSSNQPQGQPQPQQQMAFNQPQATGIGGMPQSFGNSFSSMPQQPQTGYNNNGNNGSVYGNGNFGQQPQQQQQQAKPQHTGYVPNSSMPMMNTTGTMPPPNPAQQPQLQSIQPQGTGYYQAANTANVHSVQPLQSQGTGYYVSTPNLISSNQTQQPLQAQGTGYYQSQPQQVPPPQQAQSLQPLKPQQTGFYLQPQNQAPLEPLKPTATGFVNSFANNGLNNDIKIPAIRLSFITAQDQAKFETLFRSIVTNGSNTVSGANCRKILMRSGLPPSQLARIWTLCDTSKAGELLFPEFALAMHLINDVLQGDTIPYELDSKTKNEVSSFIDAINLSIANQDSSANDAPKTPFDEFITAGVQNLQPQPTGYMPQTSFGIPLQSQITGGGVASALNPQSTGFMAPTTFNMSMNTGTPGLNPQITGGAPASMQPNITGNALQPQTTGMMPQTTGMMPQTTGMMPQTSFGVNLGPQLTGGALQSQYTGGYGSVMPQQSGPASMPNLSFNQQGLQSQLTGLQPQPTGFLPPSNFSATMPLTAQKTGFGNNEIYTKSNFNNNLIDNSSQDKISTEEKSLFYKIFETFDTQNKGLLDSPTAVEIFRKSGLNRADLEQIWNLCDINNTGQLNKQEFALGMHLVYGKLNG--KPIPNVLPSSLIPSSTKLLDNLKNQLKTEPTTTKEKPSFGKIDALSYKNNDDDVLPNYRNRRKVYSAKNEEQSSFSSPSAKSVNHSSSTLQTDDISVDKTVEKKTAKPKYAGFSREINLKNIASLENEIKNISNPENCYDSSIPSDLTSRFDAIIAKLPNLFNEISTIDNEITNAKIQLYRKKNPSSIIGSGPNGEITENDRKKAKSRALLRARMSALTGKSTESEDSLSMEDEQQSAEIKRIQQENGKNQEIIKDIRSSISDISASLKSTMTGSNMISNQEFERWEFGIGLEDGVREFLDDLKSNSNKSVTESSPFVPSSTPTPVDDRSSSPSYSQFKTAEERAAYLKEQAKKR--MKEKLAKFDKNRRNVTQSSRSISSENSREQPQQIAGSSNLVEPRATPFQEEKYVEVAQPTQPVQSTQPVQPTQPVQPTQPVQPTQPVQPTQPVQPTQPVQNVYNAKQESDDEDEDDEEKRLQEELKRLKLKKKADKEKRLAALRKQIEDAQNESDEEETNGKDNFGGHVNVPQAAPVAPSAAFSQNSTNAPRSVHAAVTPAAGKNSTGLPSTTMGHNPYFKDASASSTSTFDARAAEMQRRIQRGLDEDEDDGWSDEDESNNRVAVDNKVEEAKIGHPDHARAPPVTAAPLPSVTPVPPAVPVPQANTSNEKSSPIPIAPIPPSVTQEPPVPLAPPLPAVDGFQEPPIPSAPAIATAVQKSGSSTPALAGGVLPPPPPLPTQQASTSEPIIAHVDNYNGAEKGTGAYGSDSDDDVLSIPESVGTDEEEEGAQPVSTAGIPSIPPAGIPPPPPLP", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39013-1", "uniprot_id": "END3_YEAST", "id": "P39013-1", "name": "Actin cytoskeleton-regulatory complex protein END3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPKLEQFEIKKYWQIFSGLKPIENKVNHDQVLPILYN-SKLDSSVLNKIWFLADIDDDDNLDFEEFVICMRLIFDMVNKNISSVPDELPDWLIP-----------------------------------GSKVNLIKERKKRKQIENADLPPKKEIKVDWYMSPDDLNQYEKIYNSCAKLTDGTITFNELSTKLSTKFFNISKTDLN-------------------------------------------------------------------------------------------KVWSLINPQNLPSIDRDPTFYFIHCLRQRNDLGA------------------------------------------------------EIPASLPNSLAEVCNKKQLSYDLRSSQPPTKR-----------KEEANEVDN------------------LRDNGQNSSSDSSGSNVLSNED--------------SIKQKYASLTDDQVANMREQLEGLLNYKKSEKTQGGSKLSKRINIRSITDDLDNIEQQVEVLENYLNNKRHELQALQAEIN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P36115-1", "uniprot_id": "IRS4_YEAST", "id": "P36115-1", "name": "Increased rDNA silencing protein 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MRLSFGKQRYHGGTTVTLTEQGASDSLRAAQAIFQNHSNEVSSPCPPVTVS------------------------------------------------------------------------RNPQTRLSEPSLQKSGRKQEQKKARIRTKQVPKIKTTAPNDVELSKKHRSSPAGK-------DNVSS----------------------------TAQMAAALAHSQSKLSSDN--------NSSHSSALDTLKVLETPNLNGLLGIHSRSSSRNGSNESLTPGQR-----TPDNRSQENLLTSFSSGRRLSSSSMEPATNKDSNKALP----------------------------------------KRRPSPPLQSSLVGSGQLHENENLSSISIDSRHSLNPDTS---------------DVISNRSQTSLSQTINQLSLCESEPSIASSNTTTTTSNQGSGLPNLVPNYSSDMRKKKLVNKFKRKVFGSKPKHLSSQYEMD--ASSEELGQHEQQ-------------------------------------PSMRFKTTLRKTSVSTNAENDHASSLHEGNLRYKYNPSNDTYDVYDDTDSDSESDQNQDALTKPRKRDRIKRKIRN--------------------------------------------------------------------------------------------SANKTAHHRPIHRTRDRKFNEDKPWKSHTDITF------------------------------------------------------VTDNERKRYESMWVSNRHRHLNLLSWWPSITG-----------DSGAIN------------------------TLPEDGLILGIIVRDIWKRSNLPNSLLAEIYTKVDTRKDGTLDRKSFIVGMWLVDQCLYGRKLPNVVEQCVWDSVDRYASTTVVPVSTLKAMAKQKRKQMKEEIKNIKKENRVVLVDHNSSS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : : .. . . . * * . : . . . : * : : : .: * : . . . . : : : .. . . . * . . . : . : . :. . : : . ", "identical_positions": 5, "similar_positions": 47, "identity": "0.34%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130415-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIM1-1", "uniprot_id": "S29A1_MOUSE", "id": "Q9JIM1-1", "name": "Equilibrative nucleoside transporter 1", "aln": "--------------------------------------------------------MTTSHQPQDRY-------KAVWLIFFVLGLGTLLPWNFFMTATKYFTNRLDVSQNVSSDTDQSCESTKALADPTVALPARSSLSAIFNNVMTLCAMLPLLVFTCLNSFLHQRISQSVRILGSLLAILLVFLVTAALVKVEMD--ALIFFVITMIKIVLINSFGAILQASLFGLAGVLPANYTAPIMSGQGLAGFFTSVAMICAIASGSELSESAFGYFITACAVVILAILCYLALPRTEFYRHYLQLNLAGPAE-----------QETKLDLISKGEEPKGRREESGVPGPNSPPTNRNQSIKAILKSICVPALSVCFIFTVTIGLFPAVTAEVESSIAGTSPWK-SYFIPVACFLNFNVFDWLGRSLTAVCMWPGQ--DSRWLPVLVASRIVFIPLLMLCNVKARHCGAQRHHF-VFKHDAWFIAFMAAFAFSNGYLASLCMCFGPKKVK-PAEAETAGNIMSFFLCLGLALGAVLSFLLRALV-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O54698-1", "uniprot_id": "S29A1_RAT", "id": "O54698-1", "name": "Equilibrative nucleoside transporter 1", "aln": "--------------------------------------------------------MTTSHQPQDRY-------KAVWLIFFVLGLGTLLPWNFFITATQYFTSRLNTSQNISLVTNQSCESTEALADPSVSLPARSSLSAIFNNVMTLCAMLPLLIFTCLNSFLHQKVSQSLRILGSLLAILLVFLVTATLVKVQMD--ALSFFIITMIKIVLINSFGAILQASLFGLAGVLPANYTAPIMSGQGLAGFFTSVAMICAVASGSKLSESAFGYFITACAVVILAILCYLALPWMEFYRHYLQLNLAGPAE-----------QETKLDLISEGEEPRGGREESGVPGPNSLPANRNQSIKAILKSIWVLALSVCFIFTVTIGLFPAVTAEVESSIAGTSPWKNCYFIPVACFLNFNVFDWLGRSLTAICMWPGQ--DSRWLPVLVACRVVFIPLLMLCNVKQHHYLPS-----LFKHDVWFITFMAAFAFSNGYLASLCMCFGPKKVK-PAEAETAGNIMSFFLCLGLALGAVLSFLLRALV-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99808-1", "uniprot_id": "S29A1_HUMAN", "id": "Q99808-1", "name": "Equilibrative nucleoside transporter 1", "aln": "--------------------------------------------------------MTTSHQPQDRY-------KAVWLIFFMLGLGTLLPWNFFMTATQYFTNRLDMSQNVSLVTAELSKDAQASAAPAAPLPERNSLSAIFNNVMTLCAMLPLLLFTYLNSFLHQRIPQSVRILGSLVAILLVFLITAILVKVQLD--ALPFFVITMIKIVLINSFGAILQGSLFGLAGLLPASYTAPIMSGQGLAGFFASVAMICAIASGSELSESAFGYFITACAVIILTIICYLGLPRLEFYRYYQQLKLEGPGE-----------QETKLDLISKGEEPRAGKEESGVSVSNSQPTNESHSIKAILKNISVLAFSVCFIFTITIGMFPAVTVEVKSSIAGSSTWE-RYFIPVSCFLTFNIFDWLGRSLTAVFMWPGK--DSRWLPSLVLARLVFVPLLLLCNIKPRRYLTV-----VFEHDAWFIFFMAAFAFSNGYLASLCMCFGPKKVK-PAEAETAGAIMAFFLCLGLALGAVFSFLFRAIV-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7M7-1", "uniprot_id": "A0ACD6B7M7_DANRE", "id": "A0ACD6B7M7-1", "name": "", "aln": "---------------------------------------------------------MDPQVPKDKY-------NGVWLIFFMLGLGTLLPWNFFMTATMYFTSRL--ADPLTAMNNASMNSTEE--------DSRSVLQAKFNNVMTLCAMVPLLVFTCLNSILHQRIPQKIRIAGSLTLILLVFLLTAILVKIHLE--PLPFFIVTMVKIIFINSFGAVLQGSLFGMAGLLPASYTTPIMSGQGLAGTFAAFSMICAIASGSELHDSAFGYFITACAVISLAIASYVVLPKLEFYQYYQESRQNKPAED----------EENKMDLLKKDQRLQSAGDDD----------KKSPSIPAIFKKIWVMALSVCFAFTITIGTFPAVTVDVKSTIADGGAWE-KYFIPVSCFLFFNVFDWAGRSLTAVCMWPGK--DSKLLPALLLARVVFVPLFMLCNVQPRYNLPV-----FFTHDGWFIAFMILFAFSNGYLASLCMCFGPKKVD-PSEAETAGAIMAFFLSLGLALGASLSFLFRGLV-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPP0-1", "uniprot_id": "Q9VPP0_DROME", "id": "Q9VPP0-1", "name": "", "aln": "MPGTSDTRRLVDALDEDDEILGTEGSFVPAFRPQDHHADEQCLM-----ERQQDEVVLVSNEPESGR-------LFTYLVFYLLGIGTMTPWNFFVTAEDYWKYKFRNASINNTDLEEELT----------------PLQKSFTCDLALTATISGTTFLLLNAIFGHHVSLRTKMLGTLWMILILFGVTTGFVEINTDTWQEQFFLITLIIVVLLNISAATMSGALYGVAGLFPSEFITAVVSGQALGGILTALAFILVLAFDTGPNTTAFIFFIVGGVLILLCIVCYVILARKPFFRYYLE-------------------GGDKYKVIRAVPSHNRNGSAEGLP--------LEPILRQVMSKIYLHAISLALLYTTTLSVYPAVTVLMQSEYG-HSVWTDVYFLPVVNYLIFNCGDYFGR-LFAGWMERPL--NQNTSLLFIVVRMAFVPLFLCSNSSEHSFLPV-----LVKHDYTFIAMMVMFALSNGYFTNILLIMAPKRVK-QHEKELASSIMAAALSCGMAVGSLLSLVFVQML-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P31381-1", "uniprot_id": "FUN26_YEAST", "id": "P31381-1", "name": "Nucleoside transporter FUN26", "aln": "MSTSADTDTIKKPILAVPEPALADTHSEEISRSGEEHESENNEHSDEEGDNYSEREQSVSTEPLDTLPLRKKLKNLSYITFFAIGIGLLWPWNCILSASQYFKHDIFKDTSI--------------------------WAKIFTSSMMSFSTISSMLFNIY--LAKRQYKYSRRVINGLVWEIIVFTVMCFFTILHFLLPKWFNFMFIMMLVVISSMGTAMTQNGIMAIANVFGSEYSQGVMVGQAVAGVLPSLVLFALAFIENSSVSTTGGILLYFFTTTLVVTICVVMFSVSKISRKVNENWNVEDGHITDVLLGSLRSNEEEIRIVGRIDQMEDEDHRRTNGTRDDNDEGEELQLKVPFEVLFAKLKYLVLSIFTTFVVTLVFPVFASATYVTGLPLSNAQYIP-LIFTLWNLGDLYGRVIADWPMFRDQKFTPRKTFIYSLLRVAAIPLFLMFTAITSSSSGDEEHNGSVIVDLCYMLLQFLFGVTNGHVISMSFMKVPEQLDNDDEKEAAGGFTNIFVSTGLALGSIISYVFVFIIDFIIR", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . :: *: :*:* : *** :::* *:. : *. : : :. * : :: :: . * :::* : :. :. *:. :: ::: . * . .: .:*.:: :.: :: **.:.* :.:. :: . :: :: . : . : :. : : : : :: . . : :. : : : *: .... .: ::* : :* * ** : * . *:. :**:: . . * :: : *..:**:. .: : *:::. * * *. : :. *:*:*: :* :: :: ", "identical_positions": 41, "similar_positions": 135, "identity": "7.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130422-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A710-1", "uniprot_id": "A0A8I6A710_RAT", "id": "A0A8I6A710-1", "name": "Phosphorylase b kinase regulatory subunit", "aln": "MRSRSNSGVRLDGYARLVQQTILCYQNPVTGLLSASHDQKDAWVRDNIYSILAVWGLGMAYRKNADRDEDKAKAYELEQNVVKLMRGLLQCMMRQVDKVEKFKHTQSTKDSLHAKYNTATCSTVVGDDQWGHLQVDATSLFLLFLAQMTASGLRIIFTLDEVAFIQNLVFYIEAAYKVADYGMWERGDKTNQGIPELNASSVGMAKAALEAIDELDLFGAHGGRKSVIHVLPDEVEHCQSILFSMLPRASTSKEIDAGLLSIISFPAFAVEDVHLVNVTKNEIISKLQGRYGCCRFLRDGYKTPREDPHRLHYDPAELKLFENIECEWPVFWTYLIIDGVFNGDAVQVQEYREALEGILIRGKDGIHLVPELYAIPPDKVDEEYKNPHTVDRIPLGKLPHLWGQSLYILSSLLAEGFLATGEIDPLNRRFSTSVKPDVVVQVAVLAENSHIKGLLKQHGINVQSIADVHPIRVQPGRILSHIYAKLGQNKNMKLSGRPYRHIGVLGTSKLYVIRNHIFTFTPQFTDQHHFYLALDNEMIVEMLRIELAYLCTCWRMTGRPTLTFPVTHTMLTNDGSDIHPAVLSTIRKLEDGYFGGARVKLGILAEFLTTSFYTYLTFLDPDCD----------EKLFGDISDRSFSPDSESDLGGYLEDS----SHQESQDELDQYISHLLQSTSLKCYLP-PLCKKSEDSHVFS--AVHSTRDILSVMAKAKGLETPFFPMILPTR-VLSGHR-----KSLNLVDSPQ---PFLKKTPEYDYQWPRDDQ--DEVDCEKLVGQLKDCSNLQDQADILYILYVIKGPRWDTN---------------------LFGQHGVTVHSLLGELYGKAGLNQEWSLIRYISGLLRKKVEVLAEACADLLSHQKQLTVGLPPEPREKTISTPLPPEELTELIYEASGQDISIAVLTQEIVVYLAMYVRAQPSLFAEMLRLRIGLIIQVMATELARSLNCSGEEASESLMNLSPFDMKSLLHHILSGKEFGVERSVRPIHSSMSSPAISIHEVGHTGVTKTERSGISRLRSEMKQMNRRASADEQFFPLGQAVPKRLHSIKS-RSSTPSSPTGTSS-TDSGGHHLGWGEQQGQWLRRRRLDGAINRVPVGFYQRVWKILQKCHGLSIDGYVLPSSTTQEMTPCEIKFAVHVESVLNRVSQPEYRQLLVEAIMVLTLLSDTEMD-SIGGIIHVDQIVQLANQLFLQDQV--------SFGTTD-ILEKDQATG----------ICHLFYDSAPSGAYGTMTYLTKAVASHLQDLLPS--SGCQMQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BWJ3-1", "uniprot_id": "KPB2_MOUSE", "id": "Q8BWJ3-1", "name": "Phosphorylase b kinase regulatory subunit alpha, liver isoform", "aln": "MRSRSNSGVRLDGYARLVQQTILCYQNPVTGLLSASHDQKDAWVRDNIYSILAVWGLGMAYRKNADRDEDKAKAYELEQNVVKLMRGLLQCMMRQVDKVEKFKHTQSTKDSLHAKYNTATCSTVVGDDQWGHLQVDATSLFLLFLAQMTASGLRIIFTLDEVAFIQNLVFYIEAAYKVADYGMWERGDKTNQGIPELNASSVGVAKAALEAIDELDLFGAHGGRKSVIHVLPDEVEHCQSILFSMLPRASTSKEIDAGLLSIISFPAFAVEDVNLVNVTKNEIISKLQGRYGCCRFLRDGYKTPREDPHRLHYDPAELKLFENIECEWPVFWTYLIIDGIFNGDAVQVQEYREALEGILIRGKDGIHLVPELYAIPPDKVDEEYKNPHTVDRVPLGKLPHLWGQSLYILSSLLAEGFLATGEIDPLNRRFSTSVKPDVVVQVAVLAENSHIKGLLKEHGMTVQSIADVHPIRVQPGRILSHIYAKLGRNKNMKLSGRPYRHIGVLGTSKLYVIRNHIFTFTPQFTDQHHFYLALDNEMIVEMLRIELAYLCTCWRMTGRPTLTFPVTHTMLTNDGSDIHPAVLSTIRKLEDGYFGGARVKLGNLAEFLTTSFYTHLTFLDPDCD----------EKLFGDITDRSFSPDSEPDLGGYLEDS----SPQESQDELDQYISHLLQSTSLKCYLP-PLCKKSEDSHFFS--AIHSTRDILSVMAKAKGLETTFFPMILPTK-VLSGHR-----KSLNLVDSPQ---PLLKTTPEYDYQWPRDDH--DEVDCEKLVGQLKDCSNLQDQADILYILYVMKGPRWDTN---------------------LFGQHGVTVHSLLSELYGKAGLNQEWSLIRYISGLLRKKVEVLAEACADLLSHQKQLTVGLPPEPREKTISTPLPPEELTELIYEASGQDISIAVLTQEIVVYLAMYVRAQPSLFAEMLRLRIGLIIQVMATELARSLNCSGKEASESLMNLSPFDMKSLLHHILSGKEFGVERSVRPIHSSMSSPAISIHEVGHTGATKTERSGITRLRSEMKQMNRRASADEQFFPLGQTMSNSLHSIKSVRSSTPSSPTGTSS-TDSGGQHLGWGEQQGQWLRRRRLDGAINRVPVGFYQKVWKILQKCHGLSIDGYVLPSSTTQEMTPCEIKFAVHVESVLNRVSQPEYRQLLVEAIMVLTLLSDTEMD-SIGGIIHVDQIVQLANQLFLQDQV--------SFGTTD-ILEKDQATG----------ICHLFYDSAPSGAYGTMTYLTKAVASHLQELLPS--SGCQMQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46019-1", "uniprot_id": "KPB2_HUMAN", "id": "P46019-1", "name": "Phosphorylase b kinase regulatory subunit alpha, liver isoform", "aln": "MRSRSNSGVRLDGYARLVQQTILCYQNPVTGLLSASHEQKDAWVRDNIYSILAVWGLGMAYRKNADRDEDKAKAYELEQNVVKLMRGLLQCMMRQVAKVEKFKHTQSTKDSLHAKYNTATCGTVVGDDQWGHLQVDATSLFLLFLAQMTASGLRIIFTLDEVAFIQNLVFYIEAAYKVADYGMWERGDKTNQGIPELNASSVGMAKAALEAIDELDLFGAHGGRKSVIHVLPDEVEHCQSILFSMLPRASTSKEIDAGLLSIISFPAFAVEDVNLVNVTKNEIISKLQGRYGCCRFLRDGYKTPREDPNRLHYDPAELKLFENIECEWPVFWTYFIIDGVFSGDAVQVQEYREALEGILIRGKNGIRLVPELYAVPPNKVDEEYKNPHTVDRVPMGKVPHLWGQSLYILSSLLAEGFLAAGEIDPLNRRFSTSVKPDVVVQVTVLAENNHIKDLLRKHGVNVQSIADIHPIQVQPGRILSHIYAKLGRNKNMNLSGRPYRHIGVLGTSKLYVIRNQIFTFTPQFTDQHHFYLALDNEMIVEMLRIELAYLCTCWRMTGRPTLTFPISRTMLTNDGSDIHSAVLSTIRKLEDGYFGGARVKLGNLSEFLTTSFYTYLTFLDPDCD----------EKLFDNASEGTFSPDSDSDLVGYLEDT----CNQESQDELDHYINHLLQSTSLRSYLP-PLCKNTEDRHVFS--AIHSTRDILSVMAKAKGLEVPFVPMTLPTK-VLSAHR-----KSLNLVDSPQ---PLLEKVPESDFQWPRDDH--GDVDCEKLVEQLKDCSNLQDQADILYILYVIKGPSWDTN---------------------LSGQHGVTVQNLLGELYGKAGLNQEWGLIRYISGLLRKKVEVLAEACTDLLSHQKQLTVGLPPEPREKIISAPLPPEELTKLIYEASGQDISIAVLTQEIVVYLAMYVRAQPSLFVEMLRLRIGLIIQVMATELARSLNCSGEEASESLMNLSPFDMKNLLHHILSGKEFGVERSVRPIHSSTSSPTISIHEVGHTGVTKTERSGINRLRSEMKQMTRRFSADEQFFSVGQAASSSAHSSKSARSSTPSSPTGTSS-SDSGGHHIGWGERQGQWLRRRRLDGAINRVPVGFYQRVWKILQKCHGLSIDGYVLPSSTTREMTPHEIKFAVHVESVLNRVPQPEYRQLLVEAIMVLTLLSDTEMT-SIGGIIHVDQIVQMASQLFLQDQV--------SIGAMD-TLEKDQATG----------ICHFFYDSAPSGAYGTMTYLTRAVASYLQELLPN--SGCQMQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QI67-1", "uniprot_id": "A0A8M9QI67_DANRE", "id": "A0A8M9QI67-1", "name": "Phosphorylase b kinase regulatory subunit", "aln": "MRSRSNSGVRLDGFARLVHETILCHQNPVTGLLPASEQQKDAWVRDNVYSILAVWGLGMAYRKNADRDEDKAKAYELEQSVVKLMQGLLQCMMRQVEKVEKFKHTQSTKDCLHAKYHTPTCATVVGDDQWGHLQVDATSLYLLTLAQMTASGLHIISNLDEVAFIQNLVFYIEAAYKVADYGMWERGDKTNQGIPELNGSSVGMAKAALEAIDELDLFGAHGGPKSVIHVLPDEVEHCQSILCSMLPRASTSKEIDAGLLSVISFPAFAVEDADLVNITKAEIITKLQGRYGCCRFIRDGYRTPKEDPTRLHYDPAELKLFENIECEWPVFWTYLILDGIFNADHEQVEEYREALDGVLIRGKHGIRLVPELYAVPADKVEEEYRNPHSVERVAFGQLPHMWGQSLYILGSLLTEGFLAPGEIDPLNRRFSKEFKPDVVVQVSVVAESVQIQQLLRDHGIEVQTVSDVSPIRVMPARILSHIYVKLGNCKKLNLSGRPYRHIGVLGTSKFYEIRNGTYTFTPQFIDQHHFYLALDNQMIVEMLRTELAYLSSCWRMTGRPTLTFPITQSMLVEDGDSIDPCILSTLRKLQDGYFGGARVQMANLSSFLTTSFHTQLSFLDGDSE----------EDLLEEEEEE----DEEASAGG-------------SGDMFDQYLTDLLHSTTTKCHLP-PIQRG--QHHVFS--AEHTTRDILSFMAQVQGHNMPKPSMYLPVAPIMSKHR-----KSLNLLDVPQHKASPQTKADNVDLHLPRDSH--GNTDFVHLVDQLKHCPTLQDQADILYVLYAMKGPNWVVS---------------------LSGQGEATVRSLLEELYVRAGACKEWGLIRYISGILKKRVEVLAEACTDLISHHKQLTVGLPPEPREKVITVPLPPEELISLIYEASGQDISIAVLTQEIMVYLAMYVRSQPSLFGDMLRLRIGLIMQVMATELARSLHCSGEEASESLMSLSPFDMKNLLHHILSGKEFGVERSMRPIQSSATSPAISIHELGHTGATKTERTGIRKLKTEIKQLDD--SRPISIYSSSHSISSNVTSPRSTRCSSPSTPSGILSPTGTGDCHLQWEERQGQWLRRRRLDGAINRVPMGFYQKVWKILQKCHGLSIAGYVLPSSTTREMTEGEIKFAVHVESVLNHVPQPEYRQLLVEAIMVLTLVADMEIP-SVGGIIHIDRIVHMANDLFQQDQR--------SSGANEYFLEQDPATG----------ICNFFYDSAPSGSYGTMTYLSKAVVTYVQDFLPN--SSCLMQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W391-1", "uniprot_id": "KPBA_DROME", "id": "Q9W391-1", "name": "Probable phosphorylase b kinase regulatory subunit alpha", "aln": "MRSRSNSGVRLDYYQRIVHRLILAHQEPVTGLFPASNVNSHAWIRDNVYCILAVWGLSMAYKKIADQDEDRAKCYELEQSCVKLMRGLLMAMMNQKDKVEKFKMTQSPYDSLHAKYSSKNGLPVVDDNEWGHLQIDAVSLYLLILAQMTASGLQIVFSLDEVSFIQNLVFYIESAYSIPDYGIWERGDKTNHGEPELNASSIGMAKAALEAMNELDLFGARGGPASVIHVLADEAHKCQAVLQSMLPRESNSKELDSGLLCVIGFPAFAVDDAQLIHNTKDAILSRLQGKYGCKRFLRDGYRTPKEDPSRLYYERWELRMFENIECEWPLFYCYLILFHAFQSDKRAVEEYASRLEKIMVRSEDGILLVPESYAVPQDLVGFEYQKPGSQVREVVGRCPFLWGQSLFILGRLLQEGFLAVGELDPLNRRLGAQKKPDVVVQVVIIAEDNEIRDKLAEHDLHVQTIAEVAPIEVQPARVLSHLYTYLGRNRKLGLSGRKSRDVGILSTSKLYSLKDRIFAFTPQFADLSRFYIASDNELMIDILKGEINFLKSAWDLLGRPLVTLVLKRIHLDQD--KIPLAMIQTMRKLKSGYINGTRVMLGSLKDFLNTSAITDLSFLGSTEDGYPDRLHPDVQTYLDEHLLRSFSNRSTMNLRGGQLRPRTLRRRMSCKGAIKKTRSINVDSDNLGMEGPSPLTERRLSSIVPPPWLQANKQSHVSVFATTPEEGPTSSPLSLGNDLIRENIYPVDPHHSRSAIDRRS-EFVRQQEMPKILIQRHRAETNFADTEVEELIAMLRETENLEEQGDILQYLVDTQGLDFNTAGLGFKNKSEENATPNANNAGMLEEGRVVTVRDLLKGLYEKACQQKLWGLVRHTAGMLGKRVEDLAKAVTDLLVRQKQVTVGMPPN-NEHTITAPLPEVELRQLIHDAYGDDESTAMLTQELMVYLAMFIRTEPQLFHEMLRLRVGLIIQVMAKELSRTLNCDGEAASEHLLNLSPFEMKNLLYHILSGKEFAVS--------SVARGNLSIVSCKSSRVSKKSQIGLG------------------------------------------DPEGEDALIATID------DRQGQWLRRRRLDGALNRVPRDFYSRVWTVLEKCQGLAIEGRVLQQSLTQEMTPGELKFALEVETALNQIPQPEYRQLVVEALMVLTLVTEHNMVPSLGGVIYVEHLVHKANQLFLEDQRKVQGDATLCCAKIKDGKEQQQAASGMLLCGGAAYICQHLYDSAPSGSYGTMTYMSRAVALVLDCVPKHGEMECAIS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************ : *:*:. **.:*:*****:.**. :..**:***:*.*******.***:* **:***:**.*****. ****:*** .**.* ****** ***. *.***** : . .**.*::*****:**.**:** *********:*: .****:**********:**.:.***:********:* ****.**:*:*******::*******:** ******.**..:**::* ***** *.***:*:***.:*.******:*..*:: ** *:::***:*** **:****:**:*** **:*: **::*********:*: *:*: *..* *:** . *: :::*.:.** **** **:* : * **::* : * .*: *.:*****:**. ** ***** **:******:. . ******** ::**. .*: * .*.: **::::: **.* *.*:***:*. **. ::: **** *.:*:*.***:* ::: ::***** * :**:* **::::::*: *: :* :.* : *** :*: :.: * :* .* .::.*:***:.**:.*:** :. * .**.** * *:**. : : : : . . * . . :.: . :.* . * *: . . . . ..:. :*.:* . . .: * : . :* . :* . : : * . :.: .*: *:. .*::*.*** * :* : . * .**:.** ** :* : *.*:*: :*:* *:** **:* :**: ::**:***:**: .*: *:.*** ** .**::* *:* * *:****::*****::*::*.** :*****:***:****.**:*:*:*.*: *** *:.****:**.**:********.*. * : :** . : .:*..: *: * * : : . ::*************:**** .**.:**.:*:**:**:* * ** .* *:*** *:***:.**:.**::.*******:***:*****::: :: *:**:*:::::*: *.:** :** . . . *:: *:. **: :*******:******:::**. :: . * :.", "identical_positions": 553, "similar_positions": 355, "identity": "42.31%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130424-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2GV22-1", "uniprot_id": "PTSS2_RAT", "id": "B2GV22-1", "name": "Phosphatidylserine synthase 2", "aln": "MRRGERRVAGGSGSESPLLE----------------------GRRSTESEVYDDGTNTFFWRAHTLTVLFILTCALGYVTLLEETPQDTAYNTKRGIVASILVFLCFGVTQAKDGPFSRPHPAYWRFWLCVSVVYELFLIFILFQTVHDGRQFLKYVDPRLGVPLPERDYGGNCLIYDADNKTDPFHNIWDKLDGFVPAHFIGWYLKTLMIRDWWMCMIISVMFEFLEYSLEHQLPNFSECWWDHWIMDVLLCNGLGIYCGMKTLEWLSLKTYKWQGLWNIPTYKGKMKRIAFQFTPYSWVRFEWKPASSLHRWLAVCGIILVFLLAELNTFYLKFVLWMPPEHYLVLLRLVFFVNVGGVAMREIYDFMDELKPHRKLGQQAWLVAAITVTELLIVVKYDPHTLTLSLPFYISQCWTLGSILVLTWTVWRFFLRDITMRYKETRRQKQQS--HQA--INNGDGHP-GPEDDLPGTGTAEEEGTTNDGVPAEEGPSAAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1X2-1", "uniprot_id": "PTSS2_MOUSE", "id": "Q9Z1X2-1", "name": "Phosphatidylserine synthase 2", "aln": "MRRGERRVAGGSGSESPLLK----------------------GRRSTESEVYDDGTNTFFWRAHTLTVLFILTCALGYVTLLEETPQDTAYNTKRGIVASILVFLCFGVTQAKDGPFSRPHPAYWRFWLCVSVVYELFLIFILFQTVQDGRQFLKYVDPRLGVPLPERDYGGNCLIYDADNKTDPFHNIWDKLDGFVPAHFIGWYLKTLMIRDWWMCMIISVMFEFLEYSLEHQLPNFSECWWDHWIMDVLVCNGLGIYCGMKTLEWLSLKTYKWQGLWNIPTYKGKMKRIAFQFTPYSWVRFEWKPASSLHRWLAVCGIILVFLLAELNTFYLKFVLWMPPEHYLVLLRLVFFVNVGGVAMREIYDFMDELKPHRKLGQQAWLVAAITVTELLIVVKYDPHTLTLSLPFYISQCWTLGSILVLTWTVWRFFLRDITMRYKETRRQKQQS--HQARAVNNRDGHP-GPDDDLLGTGTAEEEGTTNDGVTAEEGTSAAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BVG9-1", "uniprot_id": "PTSS2_HUMAN", "id": "Q9BVG9-1", "name": "Phosphatidylserine synthase 2", "aln": "MRRGERRDAGGPRPESPVPAGRASLEEPPDGPSAGQATGPGEGRRSTESEVYDDGTNTFFWRAHTLTVLFILTCTLGYVTLLEETPQDTAYNTKRGIVASILVFLCFGVTQAKDGPFSRPHPAYWRFWLCVSVVYELFLIFILFQTVQDGRQFLKYVDPKLGVPLPERDYGGNCLIYDPDNETDPFHNIWDKLDGFVPAHFLGWYLKTLMIRDWWMCMIISVMFEFLEYSLEHQLPNFSECWWDHWIMDVLVCNGLGIYCGMKTLEWLSLKTYKWQGLWNIPTYKGKMKRIAFQFTPYSWVRFEWKPASSLRRWLAVCGIILVFLLAELNTFYLKFVLWMPPEHYLVLLRLVFFVNVGGVAMREIYDFMDDPKPHKKLGPQAWLVAAITATELLIVVKYDPHTLTLSLPFYISQCWTLGSVLALTWTVWRFFLRDITLRYKETRWQKWQNKDDQGSTVGNGDQHPLGLDEDLLGPGVAEGEGAPTPN-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EY42-1", "uniprot_id": "PTSS2_DANRE", "id": "E7EY42-1", "name": "Phosphatidylserine synthase 2", "aln": "MAKGEWKRSG--ADDLPLPG-------------------------RSECEVFDDGTNTFFWRAHTVTVLFILTCALVYVTLLEETPHDTAYNTKRGIVASILVFLCFGVTQAKDGPFTRPHPAYWRFWLCVSVVYELFLIFILFQTVHDGRQFMKYIDPKLGVPLPERGYGGNCLIYDPGHPTDPFHNIWDKMDGFVPAHFLGWYIKTLMIRDWWMCMIISVMFEFLEYSLEHQLPNFSECWWDHWIMDVLVCNGLGIYCGMKTLGWLSMKPYQWQGLWNIPTYKGKIKRIAFQFTPYSWVKFEWRPASNLRRWLAVLGIIFMFLLAELNTFYLKFVMWMPPEHYLVLFRLVFFVNVGGVAMREIYDFMDDPKFHKKLGQQAWIVAAITVTEFLIVVKYDPNTIMLPIPFFITQCWILGIALILVWTLWRFFIRDITLRYKETRRRRQEVS-------SERDGSSSAPSGRSKLNGSMDSVRHRKS------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :** : :* : *: :*.**:*************:********:* *********:******************************:*****************************:*****:**:**:********.*********..: **********:********:***:*********************************************:************* ***:*.*:*************:*************:***:***.*:***** ***::**************:**********:*********************: * *:*** ***:*****.**:********:*: *.:**:*:*** ** * *.**:****:****:****** :: : .: * . . . * : . ", "identical_positions": 347, "similar_positions": 61, "identity": "69.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130425-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5SW46-1", "uniprot_id": "PERL_MOUSE", "id": "Q5SW46-1", "name": "Lactoperoxidase", "aln": "-----------------------------------------------------MKVLLHLPALLASLTLLQTAASASDDPT--AETDIIHDTVEEVKVWVNKAFLDSRDR-LKMAMTTKIHSTRHLSDYLKHAKGRTRTAIRSGQVWEESLKKLSQ----------FLTNVTGQGLDLTLLSWEAGCDPP--------------APTMTCN---ISSPYRTITGYCNNRKNP-ALGSANRALARWLPAEYEDGLSLPYGWTPGKMRNGFPLPQPREVSNQIAAYLNEEDVLDQKRSMLFMQWGQIVDHDMDFAPETEMGSDTYTKAQCDEHCI--QGDNCFPIMFPPGDPKLKTQGKCMPFFRAGFVCPTPPYKSLAREQINALTSFLDASLVYSPEPSLANRLRNLSSPLGLMAVNEEVSDNGRPFPPFVKMKP---SPCEVINATAGVP---------------CFLAGDSRASEQILLATSHTLFIREHNRLATELSRLNPHWDRETLYQEARKIMGAFIQITTFRDYLPILLG-DEMQKW--------IPPYQGYNESVDPRISNVF-TFALRFGHLEIPSTVYRLDENYQPWGSESELPLHTVFFNTWRLVKDGGIDPLVRGLLAKNAKLMHQNKMMTGELRNKLFQPNHTIHG----FDLASINIQRSRDHGQPGYNSWRAFCGLSQPKTLEELSAVMKNEVLAKKLMDLYGTPSNIDIWLGAVAEPLVHRGRVGPLLTCLLGQQFQRIRDGDRFWWEN---PGVFTEKQRESLQKMSFSRLVCDNTG-IDKVPLN-PFQANAYPHGFVDCS--SIDKLDLSPWASVKE----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A400-1", "uniprot_id": "D4A400_RAT", "id": "D4A400-1", "name": "Lactoperoxidase", "aln": "-----------------------------------------------------MKVLLRLLALLASLILLQTAASARNDPP--AKTVIICDTVEEVKASVNKAFLDSRSR-LKKAMSAEVRSTRHLSDYLKHAKGRTRTAIRNGQVWEESLKKLTQ----------FLTNATGQGLDLTSLFWKVGCNPP--------------APAVTCN---ISNPYRTITGDCNNRKNP-ALGSANRALARWLPAEYEDGLSLPFGWTPGKTRNGYPLPQPREVSNQIAGYLNEEDVLDQKRSVLFMQWGQIVDHDLDFAPDTEMGTDNYTKAQCDEHCI--QGDNCFPIMFPTGDPKLKTQGKCMSFFRAGFVCPTPPYQSLTREQINALTSFLDASLVYSPEPSMANRLRNLSSPLGLMAVNEEVSDHGRPFPPFVKMKP---SPCEVINATAGVP---------------CFLAGDSRASEQILLATSHTLFIREHNRLARELSTLNPHWDGETLYQETRKIMGAFIQIITFRDYLPILLG-DEMQKW--------IPPYQGYNESVDPRISNVF-TFAFRFGHLEIPSTVSRLDENYQPWGSEPELPLHTVFFNTWRLVKDGGIDPLVRGLLAKKAKLMHQDRMMTGELRNKLFQPTHTIHG----FDLASINIQRCRDHGMPGYNSWRAFCGLSQPKTLEELSAVMENEVLAKKLLDLYGTPSNIDIWLGAIAEPLVPGGRVGPLLTCLLGHQFQRVRDGDRFWWEN---PGVFTEKQRESLQKLSFSRLVCDNTG-ITKVPLN-PFLANTYPHGFVDCS--SVDKLDLSPWAAVQK----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22079-1", "uniprot_id": "PERL_HUMAN", "id": "P22079-1", "name": "Lactoperoxidase", "aln": "-----------------------------------------------------MRVLLHLPALLASLILLQAAASTTRAQT--TRTSAISDTVSQAKVQVNKAFLDSRTR-LKTAMSSETPTSRQLSEYLKHAKGRTRTAIRNGQVWEESLKRLRQKA--------SLTNVTDPSLDLTSLSLEVGCGAP--------------APVVRCD---PCSPYRTITGDCNNRRKP-ALGAANRALARWLPAEYEDGLSLPFGWTPGKTRNGFPLPLAREVSNKIVGYLNEEGVLDQNRSLLFMQWGQIVDHDLDFAPDTELGSSEYSKAQCDEYCI--QGDNCFPIMFPPNDPKAGTQGKCMPFFRAGFVCPTPPYKSLAREQINALTSFLDASFVYSSEPSLASRLRNLSSPLGLMAVNQEVSDHGLPYLPYDSKKP---SPCEFINTTARVP---------------CFLAGDSRASEHILLATSHTLFLREHNRLARELKRLNPQWDGEKLYQEARKILGAFVQIITFRDYLPILLG-DHMQKW--------IPPYQGYSESVDPRISNVF-TFAFRFGHLEVPSSMFRLDENYQPWGPEPELPLHTLFFNTWRMVKDGGIDPLVRGLLAKKSKLMKQNKMMTGELRNKLFQPTHRIHG----FDLAAINTQRCRDHGQPGYNSWRAFCDLSQPQTLEELNTVLKSKMLAKKLLGLYGTPDNIDIWIGAIAEPLVERGRVGPLLACLLGKQFQQIRDGDRFWWEN---PGVFTNEQKDSLQKMSFSRLVCDNTR-ITKVPRD-PFWANSYPYDFVDCS--AIDKLDLSPWASVKN----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2K1A2-1", "uniprot_id": "A0A0G2K1A2_RAT", "id": "A0A0G2K1A2-1", "name": "Myeloperoxidase", "aln": "-----------------------------------------------------MKLFLALAGLLAPLAMLQTSTGATPALPGEVANSVVLDCMEEAKRLVNKAYKERRESSIKQSLRSGSASPMELLSYFKQPVAGTRTAVRAADYLHVALDLLKRKLQPLWPRPFNVTDVLTP-AQLNLLSVSSGCAYQ--------------DVGVTCP---PQDKYRTITGHCNNRRSP-TLGASNRAFVRWLPAEYEDGISLPFGWTPKVNRSGFKVPLARQVSNAIVRFPNDQLTKDQERALMFMQWGQFLDHDITLTPEPATRFSFLTGLNCETSCL--QQQPCFPLKIPPNDPRIKNQKDCIPFFRSCPACTGS--NITIRNQINALTSFVDASGVYGSEDPLARRLRNLTNQLGLLAVNTRFQDNGRALLPFDSLHD---DPCLLTNRSARIP---------------CFLAGDMRSSEMPELTSMHTLFVREHNRLATELKRLNPRWNGEKLYQEARKIVGAMVQIITYRDYLPLVLGPAAMKKY--------LPQYRSYNDSVDPRIANVF-TNAFRYGHTLIQPFMFRLDNQYRSTGPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIG-----LDLPALNMQRSRDHGLPGYNAWRRFCGLPQPSTVGELGTVLKNLELARKLMAQYGTPNNIDIWMGGVSEPLEPNGRVGQLLACLIGTQFRKLRDGDRFWWEN---PGVFSKQQRQALATISLPRIICDNTG-ITTVSKNNIFMSNSHPRDFVSCN--TLPKLNLASWKET------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11247-1", "uniprot_id": "PERM_MOUSE", "id": "P11247-1", "name": "Myeloperoxidase", "aln": "-----------------------------------------------------MKLLLALAGLLAPLAMLQTSNGATPALLGEVENSVVLSCMEEAKQLVDRAYKERRES-IKRSLQSGSASPTELLFYFKQPVAGTRTAVRAADYLHVALDLLKRKLQPLWPRPFNVTDVLTP-AQLNLLSVSSGCAYQ--------------DVRVTCP---PNDKYRTITGHCNNRRSP-TLGASNRAFVRWLPAEYEDGVSMPFGWTPGVNRNGFKVPLARQVSNAIVRFPNDQLTKDQERALMFMQWGQFLDHDITLTPEPATRFSFFTGLNCETSCL--QQPPCFPLKIPPNDPRIKNQKDCIPFFRSCPACTRN--NITIRNQINALTSFVDASGVYGSEDPLARKLRNLTNQLGLLAINTRFQDNGRALMPFDSLHD---DPCLLTNRSARIP---------------CFLAGDMRSSEMPELTSMHTLFVREHNRLATQLKRLNPRWNGEKLYQEARKIVGAMVQIITYRDYLPLVLGPAAMKKY--------LPQYRSYNDSVDPRIANVF-TNAFRYGHTLIQPFMFRLNNQYRPTGPNPRVPLSKVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIVVDEIRERLFEQVMRIG-----LDLPALNMQRSRDHGLPGYNAWRRFCGLPQPSTVGELGTVLKNLELARKLMAQYGTPNNIDIWMGGVSEPLEPNGRVGQLLACLIGTQFRKLRDGDRFWWEN---PGVFSKQQRQALASISLPRIICDNTG-ITTVSKNNIFMSNTYPRDFVSCN--TLPKLNLTSWKET------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05164-1", "uniprot_id": "PERM_HUMAN", "id": "P05164-1", "name": "Myeloperoxidase", "aln": "---------------------------MGVPFFSSLRCMVDLGPCWAGGLTAEMKLLLALAGLLAILATPQPSEGAAPAVLGEVDTSLVLSSMEEAKQLVDKAYKERRES-IKQRLRSGSASPMELLSYFKQPVAATRTAVRAADYLHVALDLLERKLRSLWRRPFNVTDVLTP-AQLNVLSKSSGCAYQ--------------DVGVTCP---EQDKYRTITGMCNNRRSP-TLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDFTPEPAARASFVTGVNCETSCV--QQPPCFPLKIPPNDPRIKNQADCIPFFRSCPACPGS--NITIRNQINALTSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHD---DPCLLTNRSARIP---------------CFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRKY--------LPTYRSYNDSVDPRIANVF-TNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIG-----LDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWEN---EGVFSMQQRQALAQISLPRIICDNTG-ITTVSKNNIFMSNSYPRDFVNCS--TLPALNLASWREAS-----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IWN5-1", "uniprot_id": "A0AC58IWN5_DANRE", "id": "A0AC58IWN5-1", "name": "", "aln": "---------------------------------------------MDTTCLETFSCLILSVFVISCLPLSATSHFPPENATVYLGSGFIQEALRRARELTDAAYAHTTDR-MKMSISEGSVRPNDLLALFKQTGPKTKAHIRAAEFLDNTVELIREMVYTHSMDKPDLSELLSA-EDMETILQATGCSAE--------------MKRPVCKSDCLSKRYRTITGHCNNRENP-QWGAANTPYARWLSPQYEDPRGAPRGWSP-----------------------------------------QHTYHNHTLPP------------------------------IPLSDPRSHTQS-CMAFFRSAPSCSSP---LGQREQLNAITAFVDSSMVYGSSDALALSLRNLSSPLGLLAVNQFHSDEGFDFMPFLNRTQPQLDPCGPRQHSDHTSAPQQKNNISMGNASFCFQAGDSRANEHLGMIALHTLFLREHNRLAEELHRINPHWSPDTLYQEARKILGAVHQILTWDHYLPHVLGRSANQIL--------MPAYKGYDPAADPSISNIFSTAAFRFAHVTVHPVVNRLGPDYRLSPAHPALPLHHSLFSSWRVVKEGGIDPVLRGLLVSPAKLQTADQMMVEELTERLFQAQGGLP-----LDLAALNLQRGRDHGLQGYSVWRELCGLPAPVNESALSGILGNTALARKLLDLYGVAENIDVWVGAIAEPALPGGRVGPLLACLIARQFRGLRDGDRFWWQN---EGVFSSGQRDALRSTSLSRIICENTR-IQQVPLD-PFTNTMRAEELLSCS--NIQLFNLSAWTEPDSDPVCGAVPRLTLGFSVLCGSAVFYQCPAGFLLIGATHVTCDPQTHHWSPQTPTCQDIDECSTDSAVCPPHLQCFNTPGGYTCTEAAAPPLSASSIAGSVMSVLGGVALIMLLLFCYQRFILRKADPPKPDCCQRTS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEJ9-1", "uniprot_id": "Q9VEJ9_DROME", "id": "Q9VEJ9-1", "name": "", "aln": "------------------------------------------------MILRILLLSLAAVAHAQYHQFGEQLQTAHGSDCALLLAGPGRSSVYDYNVNLFRGTLNPYNNGPGTCITYDAINAAYLDARKRIHVAQPKSDWKPEELATVGELLLDISIQLARTYGLSYEEIEKGLPTIDTSKTLIREVCP---------------PFFAGVECRP-GKYRRFDGLCNNIEHP-TWGAANAPFQRLIGPLYSDGINAPR-----ISVTGRDLPFSRVVSRTMHP---DDGFHDHAGTVMVIAWGQFMDHDFTLTGTPLDPINRNDPEECCKRPLHLKHPYCNEIRIPDDDYFYRLFNVKCIDFVRGFPSPRPGCKLGSRQQFNTLTGVIDANTVYGVKESFARKLRTGYG--GLMRMNPVFQEYGL--KDLLPLKLD--IPDEGCTRPNKS--------------MYCFEGGEIRVNEQLVLTCMHTLMAREHNRLATALAQINKHWDDETLFQEARRINIAIVQHVTFNEFLPILLGKEVMEKFGLVLQKD--GYWDGYDSTVNPGIIDSFAGAAFRFGHSLLPTAVERWSKAHK---FIASKRLSDLIRRPYDLYRAGVLDEYFMGLMN--QVAQAMDDSITQEVTNHLFKKEGAR----FGMDLVSFNMQRGREFGIPGYMEFRKFCGLPTSNTWDEMYGSMPNETVLR-YGSIFEHPADIDLWSGGVSEKSLPGSMLGPTFACVIATQMSYLRRGDRFWYELPNQPSSFTPEQLQEIRKAKLSRLICDNTDLIDTVQIYPMVLPDHEINPRVPCKSGIIPSIDLTKWADFG------------GHGVDPSLYNYINEIPDTLLNFRK-----------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCW2-1", "uniprot_id": "Q9VCW2_DROME", "id": "Q9VCW2-1", "name": "", "aln": "MTDETTPLTDAVPSGSGYVVLPPYQGPERVFPGGVSPRARRNKMRQFQCCMGITFIAIVFTALCLALVFSDSLGGADGGPSFFFVVN-GSDSELAPNRPLPDEPAAEWALQQAALGHHDGAQAVSAGIKALGDREILEEGLQPNEVNTPSFRHYRSLSTNPEARKLARRGYVENQATIDIAKRFNYTKQPGRSNIGWGPKIVLPDPTVLRLECDFNARYRRSTGVCNNKQHPRTYGASMVPYRRMVSPDYADGIAAPR-----VSHHGR-LPPARQVSLKIHR---SSYETDSNFTVMLAVFGQFMDHDITAT--SLTTSQEGESIDCCVAATREQHPECYPVDILPDDPYYKQYNISCMNFVRSAPAPTG--RFGPRMQLNQATAFIDASVVYGNLEQRQNQLRSFIN--GSLRM---FVTDDG--RQLLPISS---NPADGCNRVQMTRL-----------GKYCFESGDDRANENLLLTSMHLLWARHHNYLARQLQEQNPHWEDERLYQEARKILGAQMAHITYNEFLPVLLGKNISEAKGLLPAKHNLNAPDTYDPEVDPSIANCFAAAAFRFAHTLLPGLFN-ISRDNS---TPEAIELHKMLFNPFSLWAEHGIDHALMTAAN--TPVMQVDRFFSLEVTQKLFEGTAEDRVPLCGLDLVSLNIQRGRDHGIPSYPVFRRHCRLPTVDTWEEMSQAIDNATLDS-IRQIYESPQDVDVYTGALSEPPLDGAIFGPLLSCMVSDQFLRLKLGDSHWYERKMGPQKFTKAQLAEIYKTSLAAIICRNSDGITRVREHVMQRLRDGGNPHVDCQDLEGFHFNFEPWSEKQQPQDLHSAGISRGSTSVRVMSKANHQAHNVTLHIDKGI---------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . . . : : : ** * *** . * *:: . * : . * * * * *: . : .* * .. * *:* *..:*:. **. **. . * : : . * ** .*: * .* : * * *.** ** * * :*. : *:**:*:* * *: .:** :** . *. .:* * : * *:*:.* : . . * : .: : :* . : *: ::**: :** ::* ** *:.* .* :* * *. . : : . : : . ::*:: *.::* . .* ::*::. *: :: ** .*:: *: * : .:. ::* *: * * : *. ::: * ", "identical_positions": 93, "similar_positions": 118, "identity": "9.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130425-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9V4E6-1", "uniprot_id": "Q9V4E6_DROME", "id": "Q9V4E6-1", "name": "", "aln": "MIIDINPNLTPKKETAVWCDSFQHKCKVSNRTIKIFPSLLNKSNWIVSILWHICVHHTITIRNSKAREPPCKHPPITDNAEAKLTLVCSRSLKLYKIWFILILLMSTQHQVSGHGIFRQTSSSKAVFSYYQPKENITFTNLQLQNLENEAKRLETNQHPIIRAKSTPKMGLKNVFESFSKQSRDSIYNASSNKYSLINVSQSKNFPQLFNKKLSVQWINTVPIQSRQTRETRDIGLETKRHSKPSKRVDETRLKHLVLKGLGIKKLPDMRKVNISQAEYSSKYIEYLSRLRSNQEKGNSYFNNFMGASFTRDLHFLSITTNGFNDISNKRLRHRRSLKKINRLNQNPKKHQNYGDLLRGEQDTMNILLHFPLTNAQDANFHHDKIDEANVRLMLLYSSSLATNFRRGPGSRKNKISQISGNDNIERHCNFGDVNLNQSNKNSSQQLTLKVYQLLSANRRRKITSRKIEFGNVGFQETRTQWIEFDVTKAVRSWLNKSHENLGIEIQCDKCKSIGARILSDFSPSTPPRSTASSDEHLNLMPVLNIIGHGTLNSQQHGDADIHQIMLTNNRSDQYVHHRSNHDSTWRKDKWTNNCYKLHQRCCRNQLDVAFKSIKGFEFILQPKVFDAGYCHGRCPPRHNPAHHHALLQSLIWQEDHKRAPRPCCTPSKLEMLEILHVDENHSDKLKISTWSDMQVVECACS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M9QGK2-1", "uniprot_id": "A0A8M9QGK2_DANRE", "id": "A0A8M9QGK2-1", "name": "Transforming growth factor beta", "aln": "------------------------------------------------------------------------------------------------MWFINLTLLVLKLFASAEGFSTCHS-----------------------------------------------------------------YNLDDHKSKRIEAVRG-----------------------------------------------------QILSKLRIRSPPDPEASPTPQPVPAEVMLLYNSTKELLKERAR----------------------HAEAACERESSEEDYYAKEVQRVNMMPLRTDTN-SISPGPQSPYFRIVGFDVTNVERN-----------------SSTLVKAEFR---------------------------IFRAPNPQARATEQRVEIYQILKSEDVTAPSQRYIDSRTVEPRAKG-AWLSVDVTETVKEWMAFRERNLGLKISVHCPCCTFVPSTNNIVPNKS-EELEARFAGIDDDLIKQTRKPGVTKGQIEFSTKTPHLILTLLPTDR-LDSPIKKTRKKRSAADTSICTRNDQGCCLRSLYIDFRRDLNWKWIHEPKGYKANFCAGNCPYLWSADNHYNMILPLYNKMNPEASASPCCVPQDLEPLTIVYFLG---RTPRVEQLSNMVVRSCKCR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*** : *: : .*..*: * ** ..:* . *:. :. :*. * *:. ** . .*. :. : * * . :*:.. :. ..: .. *:::*:* * : :. .: * *.. :: * :**.: *: : ::** : . : : : :::**:*.:: :.* *: .* : . *:..***::*:.*: ..***::*. . . . .:: *... .. : :: : : *. :.* . .:. :::** :*: :. :: . *. *. * : .* ** ..* : *: .:::* :** :.*.:* *.** .. :*: :: .* : : : :. ***.*..** * *::. . ::. *:* * .* * ", "identical_positions": 85, "similar_positions": 164, "identity": "12.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130514-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14406-1", "uniprot_id": "CX7A2_HUMAN", "id": "P14406-1", "name": "Cytochrome c oxidase subunit 7A2, mitochondrial", "aln": "MLRNLLALRQIGQRTISTASRRHFKNKVPEKQKLFQEDDEIPLYLKGGVADALLYRATMILTVGGTAYAIYELAVASFPKKQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48771-1", "uniprot_id": "CX7A2_MOUSE", "id": "P48771-1", "name": "Cytochrome c oxidase subunit 7A2, mitochondrial", "aln": "MLRNLLALRQIAQRTISTTSRRHFENKVPEKQKLFQEDNGMPVHLKGGASDALLYRATMALTLGGTAYAIYLLAMAAFPKKQN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2R8Q5H6-1", "uniprot_id": "A0A2R8Q5H6_DANRE", "id": "A0A2R8Q5H6-1", "name": "Cytochrome c oxidase subunit 7A2, mitochondrial", "aln": "MFQHFLTLQQVSRRQISSTVRRHMANKVPDKQKLFQEANGVPVHLKGGVGDAVLYRATMSLTVVGTVCVIYELLKAAVPQKKA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::::*:*:*:.:* **:: ***: ****:******* : :*::****..**:****** **: **. .** * *:.*:*: ", "identical_positions": 44, "similar_positions": 27, "identity": "53.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130522-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P21728-1", "uniprot_id": "DRD1_HUMAN", "id": "P21728-1", "name": "D(1A) dopamine receptor", "aln": "---------------------------------------------------MRTLNTSAMDGTGLVVERDFSVR---------------------------------------------------------------------ILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFG-SFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETID-NCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKN-----CQTTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNPIIY-AFNADFRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61616-1", "uniprot_id": "DRD1_MOUSE", "id": "Q61616-1", "name": "D(1A) dopamine receptor", "aln": "----------------------------------------------------MAPNTSTMDETGLPVERDFSFR---------------------------------------------------------------------ILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFG-SFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLEDAEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN-----CQTTTGNGNPVECSQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGSEETQPFCIDSITFDVFVWFGWANSSLNPIIY-AFNADFQKAFSTLLGCYRLCPTTNNAIETVSINNNGAVMFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKREEAGGIPKPLEKLSPALSVILDYDTDVSLEKIQPVTHSGQHST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F359-1", "uniprot_id": "E7F359_DANRE", "id": "E7F359-1", "name": "Dopamine D1 receptor", "aln": "-------------------------------------------------MAVKDLNVTTVIDSGF-MESDQSTR---------------------------------------------------------------------VLTGCFLSLLILSTLLGNTLVCAAVTKFRHLRSKVTNFFVISLAVSDLLVAILVMPWKAVTEVAGFWPFG-AFCDIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPRVAFVMISVAWTLSVLISFIPVQLKWHKAQPTSFPEANASHRALLTD-NCDSSLNRTYAISSSLISFYIPVAIMIVTYTQIYRIAQKQIRRISALERAAESAKI-----RHDSMGSSSNVDS---ESSFKLSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCKRTSVGLPCISPTTFDVFVWFGWANSSLNPIIY-AFNADFRRAFAILLGCQRLCPGSN-SMETPSLNKN--------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41596-1", "uniprot_id": "DOPR1_DROME", "id": "P41596-1", "name": "Dopamine receptor 1", "aln": "MYTPHPFGFLIILVPMTNAMRAIAAIAAGVGSVAATVATSTTSSISSSTTIINTSSATTIGGNHTSGSTGFSTNSTLLDADHLPLQLTTAKVDLDIEIDIQLLTNGYDGTTLTSFYNESSWTNASEMDTIVGEEPEPLSLVSIVVVGIFLSVLIFLSVAGNILVCLAIYTERSLR-RIGNLFLASLAIADLFVASLVMTFAGVNDLLGYWIFGAQFCDTWVAFDVMCSTASILNLCAISMDRYIHIKDPLRYGRWVTRRVAVITIAAIWLLAAFVSFVPISLGIHRPDQPLIFEDNGKKYP-----TCALDLTPTYAVVSSCISFYFPCVVMIGIYCRLYCYAQKHVKSIKAVTRPGEVAEKQRYKSIRRPKNQPKKFKVRNLHTHSSPYHVSDHKAAVTVGVIMGVFLICWVPFFCVNITAAFCKT------CIGGQTFKILTWLGYSNSAFNPIIYSIFNKEFRDAFKRILTMRNPWCCAQDVGNIHPRNSD------------RFITDYAAKNVVVMNSGRSSAELEQVSAI---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..::: . . . * . ::.. ***:**: :: ** *** *: * ** :: *:*: ***::**:** ***.: .* :: *:* ** **: *****:***********.**:*** *..*::* * :* :.*.: *:. * *:.::**:*:.* *:.. . : * . .* *. ***: ** ****:* .:** * :* ***::: * *: *.. *: : . .. . .. .: . . : *. *:.******: **:*** * .** **. **.::.*:*::**::***** ** :*: ** :* . :: : . *.: ", "identical_positions": 129, "similar_positions": 111, "identity": "22.47%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130522-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P25115-1", "uniprot_id": "DRD5_RAT", "id": "P25115-1", "name": "D(1B) dopamine receptor", "aln": "-----------------------------------------------------------------------------------------------------MLPPGRNRTAQPARLG--LQRQLAQVDAPAGSA--TPLGPAQVVTAGLLTLLIVWTLLGNVLVCAAIVRSRHLRAKMTNIFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFG-TFCDIWVAFDIMCSTASILNLCIISVDRYWAISRPFRYERKMTQRVALVMVGLAWTLSILISFIPVQLNWHRDKAGSQGQEGL---LSNGTPWEEG-WELEGRTENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRS-RGAYEPDPSLRASIK-----------KETKVFKTLSMIMGVFVCCWLPFFILNCMVPFCSSGDAEGPKTGFPCVSETTFDIFVWFGWANSSLNPIIY-AFNADFRKVFAQLLGCSHFCFRTPVQTVNISNELISYNQDTVFHKEIATAYVHMIPNAVSSGDREVGEEE---EEGPFDHMSQISPTTPDGDLAAESVWELDCEEEVSLGKISPLTPNCFDKTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLD9-1", "uniprot_id": "DRD5_MOUSE", "id": "Q8BLD9-1", "name": "D(1B) dopamine receptor", "aln": "-----------------------------------------------------------------------------------------------------MLPPGRNGTAHRARLG--LQRQLAQVDAPGGSA--APLGPAQVVTAGLLTLLIVWTLLGNVLVCAAIVRSRHLRAKMTNIFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFG-AFCDIWVAFDIMCSTASILNLCIISVDRYWAISRPFRYERKMTQRVALVMVALAWTLSILISFIPVQLNWHRDKAGSQGREGL---LSNETPWEEG-WELDGRTENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRS-RGACEPDPSLRASIK-----------KETKVFKTLSVIMGVFVCCWLPFFILNCMVPFCSSGDAQGPRTGFPCVSETTFDIFVWFGWANSSLNPIIY-AFNADFRKVFAQLLGCSHLCFRTPVQTVNISNELISYNQDTVFHREIAAAYVHMIPNAVSSGDREVGEEEEAEEEGPFDHMSQISPTTPDGDLAAESVWELDCEEEVSLGKISPLTPNCFHKTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P21918-1", "uniprot_id": "DRD5_HUMAN", "id": "P21918-1", "name": "D(1B) dopamine receptor", "aln": "-----------------------------------------------------------------------------------------------------MLPPGSNGTAYPGQFA--LYQQLAQGNAVGGSAGAPPLGPSQVVTACLLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFG-AFCDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLAWTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRTYAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRS-SAACAPDTSLRASIK-----------KETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCS-GHPEGPPAGFPCVSETTFDVFVWFGWANSSLNPVIY-AFNADFQKVFAQLLGCSHFCSRTPVETVNISNELISYNQDIVFHKEIAAAYIHMMPNAVTPGNREVDNDE---EEGPFDRMFQIYQTSPDGDPVAESVWELDCEGEISLDKITPFTPNGFH---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RJ11-1", "uniprot_id": "A0A8M1RJ11_DANRE", "id": "A0A8M1RJ11-1", "name": "D(1B) dopamine receptor", "aln": "-----------------------------------------------------------------------------------------------------MLNGTVTGTEPREML-------------------------ARALTGCLLCALILWTLFGNILVCAAVLRFRHLRTKVTNIFIVSLAVSDLFVAVLVMPWKAVSEVAGFWPFG-AFCDIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPRVAFVMIGAAWTLSVLISFIPVQLDWHKAAARSGG---------------------GGNAGDCDSSLNREYAISSSLISFYIPVAIMIVTYTRIYRIAQIQIRRIASLERAAEHAQSCRSNRLACQHHSSLKSSIS-----------RETKVLKTLSVIMGVFVCCWLPFFVLNCVVPFCH----DKPSAGLPCVSDTTFDVFVWFGWTNSSLNPVIY-AFNAEFRKGFSSLLGCRGRC-RTPVETVNISNELVSYNQDTLLHKEIVSAYVNIIPNVVDD---------------TFDRISQLSRE--DEDACTDSVCELECDAEP----RAPFTANGIH---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41596-1", "uniprot_id": "DOPR1_DROME", "id": "P41596-1", "name": "Dopamine receptor 1", "aln": "MYTPHPFGFLIILVPMTNAMRAIAAIAAGVGSVAATVATSTTSSISSSTTIINTSSATTIGGNHTSGSTGFSTNSTLLDADHLPLQLTTAKVDLDIEIDIQLLTNGYDGTTLTSFYNESSWTNASEMDTIVGEEPEPLSLVSIVVVGIFLSVLIFLSVAGNILVCLAIYTERSLRR-IGNLFLASLAIADLFVASLVMTFAGVNDLLGYWIFGAQFCDTWVAFDVMCSTASILNLCAISMDRYIHIKDPLRYGRWVTRRVAVITIAAIWLLAAFVSFVPISLGIHRPDQPLIFEDNG------------------KKYPTCALDLTPTYAVVSSCISFYFPCVVMIGIYCRLYCYAQKHVKSIKAVTRPGEVAEKQRYKSIRRPKNQPKKFKVRNLHTHSSPYHVSDHKAAVTVGVIMGVFLICWVPFFCVNITAAFCK-----------TCIGGQTFKILTWLGYSNSAFNPIIYSIFNKEFRDAFKRIL-----TMRNPWCCAQDVGNIHPRNSDRFITDYAAKNVVVMNS--------------------------------------GRSSAELEQVSAI-----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * : .:.. :* **. :: **:*** *: * ** : *:*:.***::***** ***.: .* :: *:* ** *** *****:*********** **:*** *. *:** * :* *:*.: :. * *: ::**:*:.*. *: . * .*. **: ** ****:* .:** * *:* ** ::: * :: *..* *:. * . . : .: : *. *:.:*****: **:*** :* ..** .*:. **.::.*:*::**::**:** ** :*:. * :* *.* .: .:: . *.* .: . : : . * **: ", "identical_positions": 132, "similar_positions": 106, "identity": "21.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130524-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9P2F5-1", "uniprot_id": "STOX2_HUMAN", "id": "Q9P2F5-1", "name": "Storkhead-box protein 2", "aln": "-------MKKTRSTTLRRAWPSSDFSDR-------------ASDRMRSRSEKDYRLHKRFPAA------------------------------------------------FAPQASRGYMTSGDVSPISMSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFPGVPTPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQT-----------YFITPSLIR---TNSKWYHLDERIPDRSQ--CTSPQ------PGTITPSASGCVRERTLPRNHCDSCH--------CCREDVHSTHAPTLQRKSAKDCKDPYCPPSLCQVPPTEKSKSTVNFSYKTETLSKPKDS-----EKQSKKFGLKLFRLSFK--KDKTKQLANFSAQFPPEEWPLRDEDTPATIPREVEMEIIRRINPDLTVENVMRHTALMKKLEEEKAQRSKAGSSAHHSGRSKKSRTHRKSHGK--SRSHSKTRVSKGDPSDGSHLDIPAEREYDFCDP-LTRVPREGCFIIEHKGDNFIMHSNTNVLESHFPMTPEWDVSGELAKRRTEMPFPEPSRGSSHSKVHRSHSHTQDRRSRNERSNKAKERSRSMDNSKGPLGASSLGTPEDLAEGCSQDDQTPSQSYIDDSTLRPAQTVSLQRAHISSTS--YKEVCIPEIVSGSKEPSSACSLLEPGKPPESLPSYGELNSCPTKTATDDYFQCNTSSETVLTAPSP--LGKNKEDHDTLTLAEGVKKLSPSDRQVPHSSR-EPVGHKEESPKGPGGGPAASG-GVAEGIANGRLVQHHGAE-PSSLDKRKEIFSKDTLFKPLHSTLSVNSYHKSSLSLLKSHPKTPADTLPGRCEKLEPSLGTSAAQAMPASQRQQESGGNQEASFDYYNVSDDDDSEEGANKNTEEEKNR----EDVGTMQWLLEREKERDLQRKFEKNLTLLAPKETDSSSNQRATHSARLDSMDS----SSITVDSGFNSPRTRESLASNTSSIVESNRRQNPALSPAHGGAG---------PAFN---FRASAEPPTNEAEKLQKPSNCLQASVTSV-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q499E5-1", "uniprot_id": "STOX2_MOUSE", "id": "Q499E5-1", "name": "Storkhead-box protein 2", "aln": "-------MKKTRSTTLRRAWPSSDFSDR-------------ASDRMRSRSEKDYRLHKRFPAA------------------------------------------------FAPQASRGYMTSGDVSPISMSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFPGVPTPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQT-----------YFITPSLIR---TNSKWYHLDERVPDRSQ--CTSPQ------PGTITPSASGCVRERTLPRKHCDSCH--------CCREDVHSMHASTLQRKSAKDCKDPYCPPPLCQVPPTEKSKSTINFSYKTETLSKPKDG-----EKQSKKFGLKLFRLSFK--KDKTKQLANFSAQFPPEEWPLRDEDTPTTIPREVEMEIIRRINPDLTVENVMRHTALMKKLEEEKAHRSKAGSSAHHSGRSKKSRTHRKSHGK--SRSHSKTRVSKGDPSDGSHLDIPGEREYEFCDP-LTRAPREGCFIIEHKGDNFIMHSNTNVIESHFPMTPEWDVSGELAKRRTEMPFPEPSRGSSHSKVHRSHSHTQDRRSRNERSNKAKERSRSMDNSKGPLGASSLGTPEDLAEGCSQDDQTPSQSYIDDSTLRPAQTIGHQRAHIPSAS--YKEVCIPEIVGGSKEPSSACSLLEPGKTPESMPSYGELSPCPAKTAVDDYFQCNTSSETVLTAPSP--LGKNKEDHDTLTLVEGVKKLSPSERQTPHSSR-EPVGHKEESPKGPGGGPAASG-GVAEGLANGRLVQHHSAE-PSSLDKRKEIFSKDTLFKPLHSTLSVNSYHKSSLSLLKSHPKSPVDTLPGRCEKLEPSLGTSAAQAMPPSQRQQEPGGNQEASFDYYNVSDDDDSEEGANKNAEEEKNR----DDVGTMQWLLEREKERDLQRKFEKNLTLLTPKETDSSSNQRATHSARLDSMDS----SSITVDSGFNSPRTRESLASNTSSIVESNRRQNPALSPAHGGAG---------PTFN---FRASTDPPTSEAEKLQKPSNCLQASVTSV-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZTK2-1", "uniprot_id": "A0A8I5ZTK2_RAT", "id": "A0A8I5ZTK2-1", "name": "", "aln": "MPGKMEKFLQIAPHSLAIVLGPADCPAEEKPGTIQPSPQVPTQPRQLARHHIGYEIFADFKAENMQHFWNKKVTAAVAETFFLGWIDEQVLLIQGKEEHLEALREGWTRRALRPPSGFQIRCLGDVSPISMSPISQSQFIPLGEILCLAISAMNSARKPVTQEALMEHLTTCFPGVPTPSQEILRHTLNTLVRERKIYPTPDGYFIVTPQT-----------YFITPSLIR---TNSKWYHLDERVPDRSQ--CTSPQ------PGTITPSASGCVRERTLPRKHCDSCH--------CCREDMHSMHASTLQRKPAKDCKDPYCPPPLCQVPPTDKSKSTINFSYKTETLSKPKDG-----EKQSKKFGLKLFRLSFK--KDKTKQLANFSAQFPPEEWPLRDEDTPTTIPREVEMEIIRRINPDLTVENVMRHTALMKKLEEEKAHRSKAGSSAHHSGRSKKSRTHRKSHGK--SRSHSKTRVSKGDPSDGSHLDIPGEREYEFCDP-LTRAPREGCFIIEHKGDNFIMHSNTNVIESHFPMTPEWDVSGELAKRRTEMPFPEPSRGSSHSKVHRSHSHTQDRRSRNERSNKAKERSRSMDNSKGPLGASSLGTPEDLAEGCSQDDQTASQSYIDDSTLRPAQTIGHQRAHIPSAS--YKEVCIPEIVGGSKEPSSACSLLEPGKSPESMPSYGELSPCPAKTAVDDYFQCNTSSETVLTAPSP--LGKNKEDHDTLTLVEGVKKLSPSERQTPHSSR-DPVGHKEESPKGPGGGPAASG-GVAEGLANGRLVQHHSAE-PSNLDKRKEIFSKDTLFKPLHSTLSVNSYHKSSLSLLKSHPKSPADTLPGRCEKMEPSLGTSAAQAMPPSQRQQEPGGNQEASFDYYNVSDDDDSEEGANKNTEEEKNR----DDVGTMQWLLEREKERDLQRKFEKNLTLLAPKETDSSSNQRATHSARLDSMDS----SSITVDSGFNSPRTRESLASNTSSIVESNRRQNPALSPAHGGAG---------PTFN---FRASTDPPTSEAEKLQKPSNCLQASVTSV-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3B8F0-1", "uniprot_id": "A0A8M3B8F0_DANRE", "id": "A0A8M3B8F0-1", "name": "", "aln": "----MEPFLQIAPHSLAIVLSRVVAEDAPG----------VTESEEPPHHHTGYEIFADFKSLNMKYFWNKMVADAIAETFFLGWIDEHVLLIQGKEDHLEVLREAWMRRSLKPPQGFDIKYLGDVSPISMSPISQSQFIPLGEILCLAISAMNSARKTVTQETLIEHLATCFPGVPTPSMEILRHTLNMLVRERKIYPTPEGYFIVTQQT-----------YFITPSLIR---TNSKWYHLDERIPQQQQQPCTSPH------SGTMTPSTSGCVRERTHHKNHSDSYNN-------SYREDMPSTHTSTLQRRSKEHKESSPVSPPPQQ--PSEKSKSAHSFPFKTETNSKHKDGSSSSGEKQSKKFGLKLFRLSFK--KDKTKHLATFSAQFPPEEWPLRDEETPTTVPREVEMEIIRRINPDLTVENLARHTAVMKRLEEEKAQRNKANSSAQQSARSKRSRSHRKAQQSKASRSHSKTRASRGDPSDGSNLDITYDRDYRFYSSSLVRSPRETMMSMERNRGKYMVHSNPNIVESHFTTAPEWDVSGELAKRRTEMPFPEPSRAQSHSKVHRSHSHTQERKSRNERSDKAKERSRSMDNSKGPLGGPFLGPPEDF--ECSPDDR--SRYYTDDGTLRASAQANHYSRIMLSAARLHSDVCVPDVGRGSSEDAVHYRTLERSKSRDSLPAYNDLKSCSPKAPVDDYFQCTAANEVSLSAPSS--LIKPSHD-----FTDSVWKGISSERLTPHLTPPHPIEYKEETTKGQSSISVASTSQTPEHLPNGRLLHQHNPD-SGDLDKVPEVYSQETLFKSPD-------YVESSFSRPGTIGKSP-HTKSAEVLETQELFDKPLPLTVPPSS-AQEQASCAETTFDYYNVSDDD-SEETSHKNRVEEKVR----EEGGTMQWLLEREKERDLQRKFEKNLTFLSPKEGESNNSQKSVHSTRLDSMDS----SSVTVDSGFNSPRTRESLASNTSSNVENSRRQNMALSPGHMGTKRPP------PPYQPPSFRTVREPPANRTEK--------QASITSV-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VP79-1", "uniprot_id": "Q9VP79_DROME", "id": "Q9VP79-1", "name": "", "aln": "----MGTKSPGGPQRCRLILQRCLAIQLTKPG---------HTPEDFWMYDSGYMIFQNFLAANAQCWWNGPLTAATRALKYAGHVAPGMLLVTAEPCALEVLRGAFARSVLKPPATYVISSVGDIDDCIVTPTVQGQFTPLPEALCDVIMDLTAEGQSATIEHVRSKLGSRFPHMTTPATEVIYDSLAQLMQEQKIYQTSKGYFIFTPERRRSRSRPRSNHHQLNGSLAYGHLAEEEQQHGDDVVPQEARTMLMSNSEALHSLYGEISTERDGDLTHQCIQTNLADVICGGNPNDKIIYPRAAKRRSASFPTPRSLERRHSLRLFGSSKRLQRCASTRSLSKTYAQTLNTTDSSSSEYQSTDSSSPKKGSLLSRLFRRSGRAKQRQIETYSAQFPPAEWFNTRAVHLHSVGTQTAEHDMP-VAHTLSNSTFYDGSELSQRSSTLPRRHRRHMSSESTFLISSRDCSPIRRRSP-VYCSSSLPRSTQSIPATTAKTNHSSRLSHGHGGS---VTPTPPKTAQKSVIGKHIFESSPSRSATLKATAAKRHTDGLIINSCLDNKATYRSLQSSGPSSLESCKTTSMLASGPSSIDSGKVSFSQKTSGHSSLDSQCSTNTAVIAPPSNSNNGSSRSILLLNGSPRGTPRHQAMRARVAEAQAQRQRASTPSRIMEEIYPAGGSNGVPTSNSNNSITLQVTTSNGNQSIPSTKIFVQNSPVRSVITLENGKMLENSNVFIINNETMTNEKGEIIKKTLSKQTSAAPAATSTPVKPETVSEQPLSETEANSETCDSISFISECSPESTCAVEPETPVYDGGKYAKNTNNDATMNNSRKLCLQLANGIAYKN-NVLKNESQPNSPSADAPLKMAALAKQDFEIAGSVGNLNFYEKSSKDVGASQSNNMMMNSSTDLKNLCYESVCQLQKCSMNGDELALAHLLHKSSNPLGSEPNLALKDLANDKSIDKEAIDRRLSLTKESLEQGMGSVLANGGEELYNFPSLTDLSFNFTSLAARKILQGVSLNSIDTLVELNMAAAAAAAAVANNAQEKQQNNQPATAGPTASVCTDFGMV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . .* :. * : : * **:. ::* *.** ** * ** .* :.: :..* * : .:* : ** :.**: *:: .:* *::*:*** *..****.* : : :. ** ::.: * *: :*:. : * * ::.. .* : .: : .* . :. :. : .. . : .::* . :* . :. ... :..* * * * ** : : * ::: .:****** ** :: :. . : : *: ... : : :: . :: : ** *.:. : : : * * .* ::. *: :: : . .: . .. * : .:.:..*... : . :.: ...* : : : . * .* .. .* . *. * . :..* . ..:..*.. . : .. :: :.: * : : .: . .. *. . : : .:. :*:. . . . . * .:. . :: . * : . . .. : : . . ..: . . :. .* . :: . ..: . :: ::. . * . : .:. . .. . . . . : ... : .. : .* . .* . *:. . . : :. :* . .* * : :.*. . * .: : .. :* :::* :. :::.*:.* :. . . . : . : :*:. : : : . . ** .. :** ", "identical_positions": 103, "similar_positions": 313, "identity": "9.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-1000", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MA10-1", "uniprot_id": "F1MA10_RAT", "id": "F1MA10-1", "name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "aln": "---------------------MALWFPGGQLTLLLLPLLLLLLWVQQTPAGSAE-AALKVDVDLTPGSFDDQYRGCSKQVLEELNQGDYFVREIDTHKYYSRAWQKAHLTWLNQATS---------LPESMTPVHAVAILVFTLNL-NVSSDFAKAMTRASGSPGQYRQSFHFKYLHYYLTSAIQLLRKESSTKNGSPCYRVHHRMKDVNIEAN-VGSTVRFGQFLSASLLKEETQVSGNQTLFTIFTCLGASVQDFSLR---KEVLIPPYELFEVVSKNCSLKG-DLINLRSAGNVSRYNCQLLKASSKK--------CTPAPMVVLCL-CLVSVLISSKSREHRNLPAPF---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CRA0-1", "uniprot_id": "NAR4_MOUSE", "id": "Q9CRA0-1", "name": "Ecto-ADP-ribosyltransferase 4", "aln": "---------------------MALWLPGGQLTLLLL------LWVQQTPAGSTE-APLKVDVDLTPDSFDDQYQGCSEQMVEELNQGDYFIKEVDTHKYYSRAWQKAHLTWLNQAKA---------LPESMTPVHAVAIVVFTLNL-NVSSDLAKAMARAAGSPGQYSQSFHFKYLHYYLTSAIQLLRKDSSTKNGSLCYKVYHGMKDVSIGAN-VGSTIRFGQFLSASLLKEETRVSGNQTLFTIFTCLGASVQDFSLR---KEVLIPPYELFEVVSKSGSPKG-DLINLRSAGNMSTYNCQLLKACSKK--------CAPAPVVIGCL-FLVTVVISSKSRAQRNLLAPF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q93070-1", "uniprot_id": "NAR4_HUMAN", "id": "Q93070-1", "name": "Ecto-ADP-ribosyltransferase 4", "aln": "MGPLINRCKKILLPTTVPPATMRIWLLGGLLPFLLL------LSGLQRPTEGSE-VAIKIDFDFAPGSFDDQYQGCSKQVMEKLTQGDYFTKDIEAQKNYFRMWQKAHLAWLNQGKV---------LPQNMTTTHAVAILFYTLNS-NVHSDFTRAMASVARTPQQYERSFHFKYLHYYLTSAIQLLRKDSIMENGTLCYEVHYRTKDVHFNAY-TGATIRFGQFLSTSLLKEEAQEFGNQTLFTIFTCLGAPVQYFSLK---KEVLIPPYELFKVINMSYHPRG-DWLQLRSTGNLSTYNCQLLKASSKK--------CIPDPIAIASLSFLTSVIIFSKSRV-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XHY4-1", "uniprot_id": "NAR5_RAT", "id": "Q5XHY4-1", "name": "Ecto-ADP-ribosyltransferase 5", "aln": "------------------------MILEDLLMVLSCLALHILWKVQAVPI---------LPLSLVPDTFDDAYVGCSEEMEEKAG--LLLKEEMARHALLRESWEAAQEAWAHGRHK-------LTLPPGFKAQHGVAVMVYTNSSNTLYWELNQAVRTGGRSRELYMRHFPFKALHFYLTRALQLLRGTGGCSREA-GEVVFRGVSSLHFEPKRLGDSVRLGQFASSSVDERVARRFGNATFFNLRTCFGAPIQALSVFPEEREVLIPPHEVFLVTGFSQDGAQSIVTLWSYNQTCSHFNCAYLGGEKRRGCVSSR-AGQPESFSTEALALQSGKTLLLAPGELQLSRAGP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70352-1", "uniprot_id": "NAR5_MOUSE", "id": "P70352-1", "name": "Ecto-ADP-ribosyltransferase 5", "aln": "------------------------MILEDLLMVLSCLSLHALWKVRAVPI---------LPLSLVPDTFDDAYVGCSEEMEEKAG--LLLKEEMARHALLRESWEAAQEAWAHRRHK-------LTLPPGFKAQHGVAIMVYTNSSNTLYWELNQAVRTGGGSRELYMRHFPFKALHFYLTRALQLLRGSGGCSRGP-GEVVFRGVGSLHFEPKRLGDSVRLGQFTSSSVDERVARRFGNATFFNLRTCFGAPIQALSVFPEEREVLIPPHEVFLVTGFSQDGAQSIVTLWSYDQTCSHFNCAYLGGEKRRGCVSSRAVGQPEAPSTEALALQSGKTLLLDPRKLQLSRAGP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZJK0-1", "uniprot_id": "D3ZJK0_RAT", "id": "D3ZJK0-1", "name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "aln": "-----------------------MKIPAMMSLLLVSVGLRDGVQVQSYSISQLDIFSQETPLDMAPASFDDQYAGCLADMTAALP--DLNHSEFQANKVYADGWALANIQWQDRRAWGSLWGSLPPPPPGFRDEHGVALLAYTANS-PLHKEFNAAVREAGRSRAHYLHHFSFKTLHFLLTEALQLLRN---HRSPG-CRQVYRGVHGLRFRPAGPGATVRLGGFASASLKNVAAQQFGEDTFFGIWTCLGAPIRGYSFFPEEEEVLIPPFETFQVINTSRPAQGPARIYLRALGKRSTYNCEYIKEKKCRSGPCWLNSSAPGSLSASWSLLLLVLFLMLRALPENPGL----RC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60935-1", "uniprot_id": "NAR1_MOUSE", "id": "Q60935-1", "name": "GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1", "aln": "-----------------------MKIPAMMSLLLVSVGLRDGVQVQSYSISQLDIFSQETPLDMAPASFDDQYAGCLADMTAALP--DLNHSEFQANKVYADGWAQANNQWQERRAWGSVWGSLPPSPPGFRDEHGVALLAYTANS-PLHKEFNAAVREAGRSRAHYLHHFSFKTLHFLLTEALQLLRS---HRSRG-CQQVYRGVHGLRFRPAGPGATVRLGGFASASLKNVAAQQFGEDTFFGIWTCLGAPIRGYSFFPEEEEVLIPPFETFQVINTSRPTQGPARIYLRALGKRSTYNCEYIKEKKCRSGPCWLGSSAPGSISASCSLLLLLLFLVLSALPENPGLQQLTRC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1P3J5-1", "uniprot_id": "A0A8M1P3J5_DANRE", "id": "A0A8M1P3J5-1", "name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "aln": "----------------------MLVIIEALLLILAALEQDHTAAAVDRIIS----------LDMAPNSVDDQYKGCRDKMANLVKT-EYLKKEMSNSEKFRRAWKKGEDFVKDQVDS-------------LTRNNLIAIYVYSDAS--VYDDFNSNTRS--DKIEYKKKKYKWYSFHFLLTEAVQVLKK-----TQKKCFSTFRGTK-IEFNKNVLNKKVRFGSFVSSSLDRKIASYFGNKSCFEIKTCKGAEVTKYSKLPHEKEVLIPPYEVFKVTAVS----------IRKNTNKKNLWCDTVFTLKSS----------GEKSDLDCALFMKSNKTVAKYNVIH---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* ..:.* :.** * ** .: :. * .. . : : :*: :: : :: . : : : :*: ** *:*:*: .. : : . .:*:* * *:*: . : *: : * : ** ** : * .******.* * * . . . * : . ", "identical_positions": 37, "similar_positions": 56, "identity": "10.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-1004", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JTZ7-1", "uniprot_id": "A0A0G2JTZ7_RAT", "id": "A0A0G2JTZ7-1", "name": "", "aln": "MEAESPASTRASEPRALGTVGSIGSQLSRIRGKLFTWDILKTIALGQMLSLCICGTAITSQYLAEKYRVNTPMLQSFINYCLLFLVYTVMLAFQSGSDNLLEILRRKWWKYTLLGLADVEANYLIVRAYQYTTLTSVQLLDCFGIPVLMALSWFILRARYKVIHFIAVFVCLLGVGTMVGADILAGREDNSGSDVLIGDILVLLGASLYAVSNVCEEYIVKKLSRQEFLGMVGLFGTIISGIQLLIVEYKDIARIQWDWKIALLFVAFALCMFCLYSFMPLVMKVTSATSVNLGILTADLYSLFFGLFLFEYKFSGLYILSFTVIMVGFILYCSTP--TRTAEPA-ESSVPPVTSIGIDNLGLKLEESGLSETHS---------AVL-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TML3-1", "uniprot_id": "S35F2_MOUSE", "id": "Q7TML3-1", "name": "Queuine/queuosine transporter SLC35F2", "aln": "MEAESPASAGASEPRALGTVDSIGSQLSRIRRKLFTWDILKTIALGQMLSLCICGTAITSQYLAEKYRVNTPMLQSFINYCLLFLVYTLMLAFQSGSDNLLEILRRKWWKYTLLGLADVEANYLIVRAYQYTTLTSVQLLDCFGIPVLMALSWFILRARYKVIHFIAVFVCLLGVGTMVGADILAGREDNSGSDVLIGDILVLLGASLYAVSNVCEEYIVKKLSRQEFLGMVGLFGTIISGIQLLIVEYKDIARIQWDWKIALLFVAFALCMFCLYSFMPLVIKVTSATSVNLGILTADLYSLFFGLFLFEYKFSGLYILSFTVIMVGFILYCSTP--TRTVEPP-ESSVPPVTSIGIDNLGLKLEESGLPETHS---------AVL-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IXU6-1", "uniprot_id": "S35F2_HUMAN", "id": "Q8IXU6-1", "name": "Queuine/queuosine transporter SLC35F2", "aln": "MEADSPAGPGAPEPLAEGAAAEFSSLLRRIKGKLFTWNILKTIALGQMLSLCICGTAITSQYLAERYKVNTPMLQSFINYCLLFLIYTVMLAFRSGSDNLLVILKRKWWKYILLGLADVEANYVIVRAYQYTTLTSVQLLDCFGIPVLMALSWFILHARYRVIHFIAVAVCLLGVGTMVGADILAGREDNSGSDVLIGDILVLLGASLYAISNVCEEYIVKKLSRQEFLGMVGLFGTIISGIQLLIVEYKDIASIHWDWKIALLFVAFALCMFCLYSFMPLVIKVTSATSVNLGILTADLYSLFVGLFLFGYKFSGLYILSFTVIMVGFILYCSTP--TRTAEPA-ESSVPPVTSIGIDNLGLKLEEN-LQETHS---------AVL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PFN2-1", "uniprot_id": "A0A8M9PFN2_DANRE", "id": "A0A8M9PFN2-1", "name": "", "aln": "MSPQR--RRKMPREQLNTLCFKMREGLPKWR-DVFTWQLLKILLMGQGLSALICGTAVTSQYLASVYYLNTPMLQSFINYTLLGITYTMALIFRRGDGNILQILKTKWWKYLLLAVADVEANYAVVKAYQYTTLTSIQLLDCFIIPVLMILSWFFLKTRYRIIHYAAVGICLAGVGAMVGADILAGQDQGSSSDVLLGDGLVLVSATLYAISNVCQEYTVKNLSRVEFLGMVGLFGSIISAIQLGILEHKEVANIQWTWEKALLLSGYALCMYGFYSFMPVVIKRSSATAVNLSLLTGDLFSLFFGLFLFHYNFSGLYIVSLVGILIGFIMFNTVPTLSRLSDPLSDEEGVDNHTADTDNNSIEGCEGEISCAHAEQRETPPACAVINSVKL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*..: .. .: . * : : .:***::** : :** ** *****:******. * :*********** ** : **: * *: *..*:* **: ***** **.:******* :*:*********:****** ***** ****:*::**::**: ** :** ***:*********:::.*.****:** ***:.*:***:****:** **:*** **********:***.*** *:*:*::* *:* *: ***: .:****: :*****:*:* :***:***.:**.**:***.***** *:******:*:. *::***:: :.* :* :* :.. : . ** .:: *. : :*: **: ", "identical_positions": 206, "similar_positions": 98, "identity": "52.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-1010", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88803-1", "uniprot_id": "LECT2_MOUSE", "id": "O88803-1", "name": "Leukocyte cell-derived chemotaxin-2", "aln": "MIPTT-----------ILISAALLSSALAG--PWANICASKSSNEIRTCDS-YGCGQYSAQRTQRHHPGVDVLCSDGSVVYAPFTGKIVGQEKPYRNKNAINDGIRLSGRGFCVKIFYIKPIKYKGSIKKGEKLGTLLPLQKIYPGIQSHVHVENCDSSDPTAYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14960-1", "uniprot_id": "LECT2_HUMAN", "id": "O14960-1", "name": "Leukocyte cell-derived chemotaxin-2", "aln": "MFSTK-----------ALLLAGLISTALAG--PWANICAGKSSNEIRTCDR-HGCGQYSAQRSQRPHQGVDILCSAGSTVYAPFTGMIVGQEKPYQNKNAINNGVRISGRGFCVKMFYIKPIKYKGPIKKGEKLGTLLPLQKVYPGIQSHVHIENCDSSDPTAYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F1W2-1", "uniprot_id": "E7F1W2_DANRE", "id": "E7F1W2-1", "name": "", "aln": "METNTYRIMRLDILFCFLVWAVLSCSCVRDRVKFGPLCSGNKDNTKRGCDVNYGCGHYGASRGSRKHMGLDIVCTDGAYVYAPFDVRIIGRAKPYGNNNAIDDGITLMGEGLCFKLFYVQPDLLSGTKFKYEKIGSLLPMQKVYPGITSHVHVQMCDKSDPTEYF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ... *: * * .:.: . :. :*:.:..* * ** :***:*.*.* .* * *:*::*: *: ***** *:*: *** *:***::*: : *.*:*.*:**::* .*. * **:*:***:**:**** ****:: **.**** *:", "identical_positions": 68, "similar_positions": 50, "identity": "41.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-1015", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43193-1", "uniprot_id": "MTLR_HUMAN", "id": "O43193-1", "name": "Motilin receptor", "aln": "MGSPWNGSDGPEGAREPPWPALPPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVTVMLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGPLLCRLSLYVGEGCTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVGVEQDPGISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECRPS--PAQLGALRVMLWVTTAYFFLPFLCLSILYGLIGRELWSSRRPLRGPAASGRERGHRQTVRVLLVVVLAFIICWLPFHVGRIIYINTEDSRMMYFSQYFNIVALQLFYLSASINPILYNLISKKYRAAAFKLLLARKSRPRGFHRSRDTAGEVAGDTGGDTVGYTETSANVKTMG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RMH9-1", "uniprot_id": "A0A8M1RMH9_DANRE", "id": "A0A8M1RMH9-1", "name": "Growth hormone secretagogue receptor type 1", "aln": "MEDHHCG----------------------ASLFPTSTLIPVTTICIFLFIIGVTGNTMTILIIQRFKDMKTTTNLYLSSMAISDLVIFLSLPFDLYRLWKYVPWIFGEFVCRLSHYINEGCTNATILHITVLSMERYLAICFPFKAKAAITKRRVKYVILALWGFALLSAAPMFFLMGVEYEN---------------------------ETMPDPG--------------SRQCKHTRYAIESGLLHTTIWVSTAYFFCPMFCLLFLYGSIGRKLWKSRHELHGPNAAARQKVNRQTVKILAVVVSVFAICWLPYHIGRFLFTHVDDYHSARLSQNFNVASMVLFYLSASVNPVLYNLMSNKYRSAVKRLFLL----PRGYQGTNRRHISTRDDITETLNGVKETMMTEDD--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . * .* ** .:*:***::*: **::**:**.:*:::* *::**:*******.***:***:*:*.*********: **:** ::**** *:.**** **:**:*.**:******* *::*:. :*:***: :* .**..*****.*::**:*** : . * *. **:*: : . : * *:. :**:***** *::** :*** ***:**.**: *:** *:.*:: :****::* *** .* *****:*:**::: :.:* : :** **:.:: *******:**:****:*:***:*. :*:* ***:: :. .. .* * .** . . ", "identical_positions": 173, "similar_positions": 108, "identity": "41.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-1022", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A9L6KDU4-1", "uniprot_id": "A0A9L6KDU4_MOUSE", "id": "A0A9L6KDU4-1", "name": "", "aln": "MPVDSLPNSILAHMLAISNVPPPPLHSLPRLRLSKTINYGQLNALCHIRGLKSDQHSSLRSEAHDAFIKQYPQIFLREKTVLPKVSHQVDKRKSALKLAEKKH-QPVMAHNISAYLREARGGPSIDEKEITEEKFQEFLNILKKLPVYRTTHEHNMVWKILQSIPELTSQFSNEDLKILSKKVISETWIKGSTVIGDDGLYVLLTGQARRRVKVFRSLIEENDS--IITSLYRDSFLFDAELQDSTVAQLYVPSKKLIVKQWGIFGSLKDR--AEMDERDRSVVTDYDCEILKIAAKEYEKLKLEKVKHENAQKLKLIRKCPFYETWPTLSIWELVSICKFKNFPPGHVLVESGTVISFVGYINSGYCNIYRNVVGLVDLPINKVKKIKKLVYMGKLKEKESFGEISILLQAPFTCTVITGQEVEMAVIEDKDIQVYGN----------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NA66-1", "uniprot_id": "CNBD1_HUMAN", "id": "Q8NA66-1", "name": "Cyclic nucleotide-binding domain-containing protein 1", "aln": "MPMSSLPAAILSHMTAINNVPPPPLHSIPNLKKSKHINYGQLNALCHIRGQHSRSMSNILS-AHDTFMKQYPKVFLHQKPRLPKLFKQEEQRELNEGKEESQHQQPDDSNNIAVHVQRAHGGHILYRPKRATEKFEEFLAILKKLPIHRTPYEHKTVWKFLKTIPDLTFQLNDKHLKTLSKTVFSETWLKGSTVVANDGFYVILKGLARPQTNVYKNLIEGSDSPDSFISQSFHSFIWSEEFKNSTLAEMYLPSYDSMLSKWSTFGTLEVMPQNESETQMFSVVTEDDCEILKIPAKGYAKIKEEKIKLENMQKLKLIRMCPYYEEWPTLSIYELIALLKWKKFPPGHVIVESGNIISFVGYINSGCCNIYRSIIGFVKLRSNKVKRSQKLVYMGKLKEKESFGEISVLLQVPFTCTIITKKEVEMAIIEDKDLFVA------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FDP1-1", "uniprot_id": "E7FDP1_DANRE", "id": "E7FDP1-1", "name": "", "aln": "----------------------MSRGRNSAEQRHADIDYTQLKRLIQLN-----DSMSSAEETHKGFMELYDGIFQQPQTSLPKKQLKG-------------RMHPPVKPSLYESVQEVN-RHQPHGKLAQESLMNQAIKALKKLPIERSQSEHHVINKLLKGVHSLNSQLGLQELKQISTITTVETWDRGQIIFAHNGFYLVLKGSVKP-------------------------FNHETLREDQTVSTIATG---------GSFGSCEPVNAAEGSDIVQCVLTLETCEILKISRSGYEKLKKDILARDHEVKAALIQGCQLYLHWPKLSINHLVDGMQLKTFPANQVLVKEGKICSFVAFIARGECNILQDARSLIKSVDTKSCRVR-SVVVGKLGPKQSFGEVSILLDQPSPCTVITATEVHGGIIQPECVKGLDSVTTALILQTAQPVCGKLSEEEVMKEFLTQERMKKWELEKRKILSAALFYNGVQPGRGKWTFNRGPRGKTEKSNKSI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : *:* **: * ::. . . . :*. *:: * :* : :. *** : : :* .: ::... . ::: : *****: *: **: : *:*: : .*. *:. :.** :*. . *** :*. :...:*:*::*.* .: * . ::.*:: : . **: : * . .*:* ******. . * *:* : : :: * **: * * **.*** .*: : *.**..:*:*:.*.: ***.:* * *** :. .::. .* : : * :*** *:****:*:**: * .**:** **. .:*: : : ", "identical_positions": 98, "similar_positions": 121, "identity": "19.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-1023", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LF28-1", "uniprot_id": "A0ABK0LF28_RAT", "id": "A0ABK0LF28-1", "name": "", "aln": "MDPPEKDDKAKPRDEDSEKEQISESTMTPPRKDDEAIPKDEGSEKEQTTETKMTPPEKDAEMVTKVKGPEQEQTTESPTTPPKKDDKATPKEEGSEEEQKPPESPTTPPKKDDKATPKEEDSEQEQKSPESTITPEKDDKGTQKDEGSEEEQPSSESPTTPPKKDDKATTKEEGSEEEQKPPESPTTPPKKDDKATPKEEGSEKEQKSPESTTTPPKKDDKATPEEEGSEKEQKSPDSPTTPPKKDDKATLNEEGSEKEHKSPESTTPPKKDDKATPKEEGSEKEQKSPESPTTPPKKDDKATPKEEGSEEEQKSPESTTPPKKDDKATPKEEGSEKEQKSPESPTTPPKKDDKATPKEEGSEEEQKSPESTTPPKKDDKATPEEERSEKEQKSPESPTTPPKKDDKATPKEEGSEEEQKPPESTTPPKKDDKATPKEEGSEKEQKSPESPTTPPKKDDKATPKEEGSEEEQKPPESTTTPPKKDDKAIPKKEGSEEEQISPESKTTPPEKGAKMIPEFQGPEQEQTSES--PTTPPKKDDKAIPKDEGSEKEQTSESKITPEKSDKASPKDKGSEEEQTSESKITPPRKDDKAIPKGERSEEEQTSPESKITPEKSDKASPKDKGSEEEQTSESKITPPRKDDKAIPKEERSEEEQTSSESTTTPPKKDDKAIPKKEGSEEEQISPESKTTPPEKGAKMIPEFQGPEQEQTSESPTTPPKKDDKAILKDEGSEEEQISESKITPPRKDDKAIPKEERSEEEQTSSGLAEERIVTPEKHDKATQKDQGSEEEQIPESTTTPPEKDDEAIPKDEGSEEEQISDYKAHVIAKFDTSVDLH-------CDGPEMKVLSDAFKPH-QKTFRPHTIILHGRPGVGKSALARSIILGWAQGKLYQDMS-YVFLFSVREMKWTEKSS-LAQLMANEWPHSQAPVTKIMSQPERLLFVIDGLDDMDSALQHDDMTLSRDWKDKQPIYILVYSLLRKALLSQSFLIITTRNTGLENLRSMVVSPLYILVEGLSASRRSQLVLENIPDDHQKIQVFHSVIENHQLFDQSQAPSFCSLVCEALQLQEKLGKRCTLPCQTLTDLYATLVFHQLTSRGPSQRALSKE-----EQITLVGLCRMALEGVWTMRSVFYDDDLKSYSLKQ-SEISALFHVNILLQVGHSSEQCYVFFDLSLQDFFAALYYVLEGLG-EWNQYFSYITNQRNIMEVKRS------------------SDSHLLEMKRFLFGLMNKDTLKTVEVLFRCPVTPPIKQKLQHCLSLIGQQVNGSSPMDTLDAFYYLFESQDEEFVHMALKSFQEVWLLINQKMDLMVSSYCLQQCQNLKAIRVDISDLFSVDNTPKLCP-VALQKTQCKPLIIE--WWENFCTVLS-----THPNLKTLDLGHSILNEWSMKILCLKLRNSSCSIQNLTFKNSEVVSG--LQYLWMLLVSNRNLKYLNLGNTPMKDDDIKLACEALKHPSCSLETLRLDSCELTLTGYELISKLLLSAS-SLKCLSLARNKVGVKSMTSLGEALSSSTCTLQKLILDGCDLIPVSCHMLTSALSS-NRNLTHLCLSNNSLGTEEVQQLCQFLKKPECALRRLILNHCNIIKDAYGFLALILANNRKLTHLSLTMNPVGNSAMKLLCEALKEPTCYLQDLELVDCQLTENCCEDLACMITTTK-HLQSLDLGNNALGDKGVITLCKGLKQSSSSLRRLGLAA-------CGLTSKCCEVLSSALSCNPYLNS------LNLVRNDFNTSGMLKLCSAFQNPASNLWIIG------------LWKQQFYAQVRRQLEEVQFIKPHVVIDGDWYSIDEDDRNWWKN-----------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R1M5-1", "uniprot_id": "NALP5_MOUSE", "id": "Q9R1M5-1", "name": "NACHT, LRR and PYD domains-containing protein 5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGPPEKESKAILKARGLEEEQKSER--KMTSPENDSKSIQKDQGPEQEQTSESTMGP---------------------------------------------------PEKESKAILKARGLEEEQKSERKMTSPENDSKSIQKD------------------------------------------------------QGPEQEQTSESTMGPPEKDSKAILKARGLEEEQKSESTMSPSENVSRAILKDSGSEEVEQAS---ERKMTSPENDSKSIQKDQGPEQEQTSETLQSKEEDEVTEADKDNGGD---LQDYKAHVIAKFDTSVDLH-------YDSPEMKLLSDAFKPY-QKTFQPHTIILHGRPGVGKSALARSIVLGWAQGKLFQKMS-FVIFFSVREIKWTEKSS-LAQLIAKECPDSWDLVTKIMSQPERLLFVIDGLDDMDSVLQHDDMTLSRDWKDEQPIYILMYSLLRKALLPQSFLIITTRNTGLEKLKSMVVSPLYILVEGLSASRRSQLVLENISNESDRIQVFHSLIENHQLFDQCQAPSVCSLVCEALQLQKKLGKRCTLPCQTLTGLYATLVFHQLTLKRPSQSALSQE-----EQITLVGLCMMAAEGVWTMRSVFYDDDLKNYSLKE-SEILALFHMNILLQVGHNSEQCYVFSHLSLQDFFAALYYVLEGLE-EWNQHFCFIENQRSIMEVKRT------------------DDTRLLGMKRFLFGLMNKDILKTLEVLFEYPVIPTVEQKLQHWVSLIAQQVNGTSPMDTLDAFYCLFESQDEEFVGGALKRFQEVWLLINQKMDLKVSSYCLKHCQNLKAIRVDIRDLLSVDNTLELCPVVTVQETQCKPLLME--WWGNFCSVLG-----SLRNLKELDLGDSILSQRAMKILCLELRNQSCRIQKLTFKSAEVVSG--LKHLWKLLFSNQNLKYLNLGNTPMKDDDMKLACEALKHPKCSVETLRLDSCELTIIGYEMISTLLISTT-RLKCLSLAKNRVGVKSMISLGNALSSSMCLLQKLILDNCGLTPASCHLLVSALFS-NQNLTHLCLSNNSLGTEGVQQLCQFLRNPECALQRLILNHCNIVDDAYGFLAMRLANNTKLTHLSLTMNPVGDGAMKLLCEALKEPTCYLQELELVDCQLTQNCCEDLACMITTTK-HLKSLDLGNNALGDKGVITLCEGLKQSSSSLRRLGLGA-------CKLTSNCCEALSLAISCNPHLNS------LNLVKNDFSTSGMLKLCSAFQCPVSNLGIIG------------LWKQEYYARVRRQLEEVEFVKPHVVIDGDWYASDEDDRNWWKN-----------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P59047-1", "uniprot_id": "NALP5_HUMAN", "id": "P59047-1", "name": "NACHT, LRR and PYD domains-containing protein 5", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKVAGGLELGAAALLSASP-----RALVTLSTGPTCSILPKNPLFPQNLSSQPCIKMEGDKSLTFSSYGLQWCLYELDKEEFQTFKELLKKKSSESTTCS---------------------------------------------------IPQFEIENANVECLALLLHEYYGASLAWATSISIFENMN----------------------------------------------------LRTLSEKARDDMKRHSPEDPEATMTDQGPSKEKVPG--ISQAVQQDSATAAETKEQEISQAME--QEGATAAET-----------EEQEISQAMEQEGATAAETEEQGHGGD---TWDYKSHVMTKFAEEEDVRRSFENTAADWPEMQTLAGAFDSD-RWGFRPRTVVLHGKSGIGKSALARRIVLCWAQGGLYQGMFSYVFFLPVREMQRKKESS-VTEFISREWPDSQAPVTEIMSRPERLLFIIDGFDDLGSVLN-NDTKLCKDWAEKQPPFTLIRSLLRKVLLPESFLIVTVRDVGTEKLKSEVVSPRYLLVRGISGEQRIHLLLERGIGEHQKTQGLRAIMNNRELLDQCQVPAVGSLICVALQLQDVVGESVAPFNQTLTGLHAAFVFHQLTPRGVVRRCLNLE-----ERVVLKRFCRMAVEGVWNRKSVFDGDDLMVQGLGE-SELRALFHMNILLPDSH-CEEYYTFFHLSLQDFCAALYYVLEGLEIEPALCPLYVEKTKRSMELKQAG-----------------FHIHSLWMKRFLFGLVSEDVRRPLEVLLGCPVPLGVKQKLLHWVSLLGQQPNATTPGDTLDAFHCLFETQDKEFVRLALNSFQEVWLPINQNLDLIASSFCLQHCPYLRKIRVDVKGIFPRDESAEACP-VVPLWMRDKTLIEE--QWEDFCSMLG-----THPHLRQLDLGSSILTERAMKTLCAKLRHPTCKIQTLMFRNAQITPG--VQHLWRIVMANRNLRSLNLGGTHLKEEDVRMACEALKHPKCLLESLRLDCCGLTHACYLKISQILTTSP-SLKSLSLAGNKVTDQGVMPLSDALRVSQCALQKLILEDCGITATGCQSLASALVS-NRSLTHLCLSNNSLGNEGVNLLCRSMRLPHCSLQRLMLNQCHLDTAGCGFLALALMGNSWLTHLSLSMNPVEDNGVKLLCEVMREPSCHLQDLELVKCHLTAACCESLSCVISRSR-HLKSLDLTDNALGDGGVAALCEGLKQKNSVLARLGLKA-------CGLTSDCCEALSLALSCNRHLTS------LNLVQNNFSPKGMMKLCSAFACPTSNLQIIG------------LWKWQYPVQIRKLLEEVQLLKPRVVIDGSWHSFDEDDRYWWKN-----------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TQT1-1", "uniprot_id": "A0AB32TQT1_DANRE", "id": "A0AB32TQT1-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAEDVFVCVGPKSSASSCVSVKSDGSMRHPPDLSEETCNIRQEESRTASCP------------------------------------------------------------EPSCVSMKSDGSMRHPPDLSAEPATSEPLN----------------------------------------------------KSLVRTRQRSEPSCVSVKSDGSMRHPPDLSAEAVTSDHLVDRDDQTNTLKRVSRQQVDQLQQVKDEHKASMKDKYESLYEPVKLQDNQTLLNSIYTQLYIIEGESEWVKDED--------------FEKSPTAQ-------QSQDTLIYCNDIFKTSSQVKDEIRVVLTKGIAGIGKTVSVQKFILDWSEGRANQDVD-FLFVLPFRELNMIKDHQYSLHSLLRDFHPKLQNLDSRIYEQCRVVFIFDGLDESRITLNFSDCEKVCDVNESSSVGVLTSNLIRGDLLPSALIWITSRAAAASQIPSKYIN-RVTEIQGFDEPQKREYFTRRIGNEEQANTIISHVRKARSLHIMCHIPVFC---CISATVLENIITRGSEIPQSLTEMYIHFLLIQIHVNNQKYEERDPEKVLESNRGLIVKLAELAFRQLMKGNVMFYEEDLTESGMDIDAAVYSGICTAFKQELVIQQRKVYSFIHLSFQEFLAAFYAFYCHLTKNRKPLQEFLREEYSQQDRKSPRSSLYELLTSAADKTLKSKNGRLDLFLRFLLGISLESNQRLLKDLLTHTESSTDTIGETAQYIKQRVNCYNLSADRSINLFLCLLEVNDQTLSR-EIQEFIRSDKHSEEKLSPVHCSAIAHMIQMSEEVLEEFEPIKYNTSYEGRWRLIPAVLNCRKALLTGXCLSDEHCDSLSSALQSANSHLIELDISTNDLLISGVSQLCDALKSSHCQLRILRLAGCRLSDQDCKSLSSVLQFPNSPLRELDLSNNDLQESKLELLCAGLEDSHCQLNTLRLSGCCLSDKHCGTLASALQSSNSCLRELELSNNDVQDSGVKLLSAALKSSHCQLNTLRLAGCRLTGQCCESLSSALQSSNSKLRGLDLSNNNLQDSGVMLLSAGLKSSRCQLETLRLAICDLTGVSCESLSSALQSTECLRELDLSNNDLQDSGLKRLSAGLESLHCQLETLRLSGCMVSEDGCRYASAALSSTHSRLTELDLSYNHPGASGVSLLSDLQKNPNSALDKIHVDHGGEFRITAGLWKYACDLTLDPKTANSNLTLSEDSRKVTYVEEKQSYPDHPERFDGWPQVLCREGLSGRCYWEAEWTGYAVISVAYKAIWRKGWNEFSEFGYNRNNRNSWSLICDEAFTACHDHKETVIRVPSSSWRRVGVYVDCSAGTLSFYSVSNTLTHLHTFTCKFTEPLYAGFGIYRLNSSVSLCKFEATHIHARD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * :. * . : ::: *.: . : . . : : : .. . :. : . . * . : . : .: . :. :. ::: :: .. : * . : . : . *.. : . :.:: :* .*:**:. .: ::* *::* * : :::.:..**:: :. . . : .: . : . : . *::*::**:*: .*: .* * :... * .*:* **..::: :* * .. .:: * :. :.*:. :: . . .. .: : : : : :.* .: * . * : : . : : *:** :: ::: *: . . * :: : :. :* . : . . :* :** .: : : : : : .: * * .**:*:* **:* . * : :: : : * . . : : ***:*: :. : :: *: . : :. ::: * *:* :*: : :: * . ::::. .* : . : :. : . : *.*: :.* *. : :* **:. . * .:. ** *: * :: * : ...: . : ..* *: *:*... :::..:.: * .*:.. * :::***. * *: :: * :: *: *.*: * * ..: *. ** * * *:.* * .* : *. * *** * * .* * ****.* . * *. :: ..* *. * * *.: . *: * .. * .*.*: * : :..:* *. :.. * *: *.* * :: *. :. :: :: :* .*** * * ** *.. *: .* * :: : . * . .*: . :.* *. :. *.:. . . : ..: .. : * : . : . *: :*.. . . ..* :: :: ", "identical_positions": 163, "similar_positions": 373, "identity": "8.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-1027", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F8WLE0-1", "uniprot_id": "KIF28_RAT", "id": "F8WLE0-1", "name": "Kinesin-like protein KIF28", "aln": "MDCEKMGKLPVPRTDSVRVAVRVRPFSQREKNSGSQCVISMHAR-SITIRDPKDAELVKTFTFDLAYWSHDGFQKDEDGVLIPSDPTSKFAGQSDVFHDIGRGILDSAWQGYNATLLAYGQTGSGKSYSMIGYGANKGIIPRVCEELFQAIEKQKESLEAQVMFSMLEIYNEQIRDLLSR-TKAPGGLRVREDQRLGFFVEGLKWVPCEDSVQIEKLVEQGSKIRMTASTNMNASSSRSHMLIAIRFKQVFLDTALTKQSSINMVDLAGSERQRSSGSEGDRLREGSRVNLSLTNLGNVISALADLAMGKKVLHIPYRDSVLTKLLQSALGGNSRTTLIAALSPADICYEETLSTLRYAERAKKVRNRAVIN---TCPLVRASRAENALLLGFGGAGAAEHSACFWAEQQL------------GTWGTWAQLLEQARREWEQQYMALAQEQQMVKILPHLLNVNEDPQLTGVLKFFIHN-GSCEVGR--AASNAICLQSLGISDKHASFTNMDGKVTVAPHITGKVIVNGVPVSSRTKLQHLDRIILGSNSAFLYIGFPSERGAEDLGRFDYDFFQMERAAAEGVSVDMLGTASPG-DDQADPSILAVFQDYIKLMPLVVEANQMSEELKKGLKMELKVKNLASSDSRGCDLQKEVMVKVTKQGTHEVWIWSKAKFINRKFLMEELYQRFLES----RDSHVAQEDDPFWDPVEVLHLGSAHVWLQSLAHRMMLEEQVEFLNCEGLEEAVLHIQITPCSPEGWAHGEEDTVIDPLELLGKRIDFQIHIVQCLGVKWLKEDATRGIQLGYKVYDLPNTLYTKPVWQSVNPRVEESVHFAALGVSREFLNYLLTNALVVDLWGLQEGCAHLGVSQPDVLFTGEGYIMVDTKTFSSVKD---ITSNQVPELYQKLLKLEQETELLRDINRALRGENVYLKAALENAGSAPQGERRYHKPDNPEGATVTAAGEAKQMCAQRASSDSQLARALKVFYGGMSVARGQLLRLRQCRPPEDDQML--RPFVHQQSQMLKDLEDLLESSLQKLKSDVAFIVKKKKEYLLPRGR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YXS5-1", "uniprot_id": "KIF28_MOUSE", "id": "D3YXS5-1", "name": "Kinesin-like protein KIF28", "aln": "-----MGRVPVPRSDSVRVAVRVRPFSQREKNSGSQCVISMHSG-NISIRDPKNEERVKTFTFDLTYWSHDGFQKDEDGVLIPSDPASKFAGQSDVFHDIGRGILDSAWRGYNATLLAYGQTGSGKSYSMIGFGTNKGLIPRVCEELFQAIEKQKENLEPQVMFSMLEIYNEQIRDLLSR-TKAPGGLRVREDQQLGFFVEGLKWVPCENYAQIEKLVEQGSKIRMTASTNMNASSSRSHMLIAIQFKQVFLDTALTKRSSINMVDLAGSERQRSSGSEGDRLREGSRVNLSLTSLGNVISALADLAMGKKVLHIPYRDSVLTKLLQSALGGNSRTTLIAALSPADICYEETLSTLRYAERAKKVRNRAVIN---TCPLARASRAENALLLGFRGAGAAEHPACFWAEQQL------------GNQGTWAQLLEQARREWEEQYEALTQEQKMVRILPHLLNVNEDPQLTGVLKFFIHN-GSCDVGR--AASNAICLQGLGISDKHASFVNLDGKVTVAPHSKCKVIVNGVPVTGRTKLQHLDRIILGSNSAFLYVGFPSERGAEDLSRFDYDFFQLERAAAEGVSVATLGCVSPG-DDQADPSILAVFQDYVKLMPLVVEANQMSEELKKGLTMELKVKNLASSDSRGYDLQKEVMVKVTKQGTHEVWIWSKAKFINRKFLMEELYQRFLES----RDSHVAQEDDPFWDPLEVVHLGSAHVWLQPLAHCMMLEEQVEFLNCDGLEEAVLHIRITPCSPEGWAHGEEDMVIDPLELLGKRIDFQTHIVRCLGVKWLKEDGSRGIQMGYGIYDLPNTLYTKPVWKSVNPRIEETVHFAALGASREFLDYLLTNALIVDLWGLQEGCAPLGVSQLDVLLTGEGHIMVDTKTFSSVKDVSQITSNQVPELYQKLLKLEQETELLRDVNRALRGENVFLKASLENAGSAPQAQ----KLDNPEGATRTAAREAKQVCAQQASSDAQLARALKVFYQGMGVARGQLLRLRRCRPPEDDQML--RPFVHQQSQMLKDLEDLLESSLHKLKADVAFIVKKRKEYLLPSQQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B7ZC32-1", "uniprot_id": "KIF28_HUMAN", "id": "B7ZC32-1", "name": "Kinesin-like protein KIF28P", "aln": "--------MPTQSVDSVK-AVRVRPFSQREKNSGSKCVISMHSRTTTTTQDPKNPEHVKTFTFDLAYWSHNGFQRDKDGVLISADPSRKFAGQRDVFHDLGRGILDSAWQGYNATLLAYGQTGSGKSYSMIGFGCKQGIIPTVCEELFRAIENQGRNQEHQVMFSMLEIYKEIIRDLLSR-TKKPGGLRIREDQQLGFYVEGLKSVPCENYAQIERLMEQGTKIRTTASTNMNASSSRSHLVITIQFKQVFLDRDLTKQSSINLVDLARSERQKSSGSEGDRLREGSCVNLSLTNLGSVISVLADAAMGKKVLHIPYRDSVLTKLLQSALGGNSRTALVAAVSPADICYEETLSTLRYAERERKIRNRAVAN---TWTLMRKSRAENSKLL-------------------------------------------------------------PMMTFPHLLNLSEDPQLTRVLKYFIQA-GTQPAPCP-RPALSPPHPALRISDKHASFTNADGKVTVTPHSKCKVAVNGVPITTRTKLQHLDRLILGSNSTYLYVGFPSEWGSEDLSRFDYDFFQLERAAAEGASADKLGAADGG-DGKAGPSVLAAFQDYIKLMPLVSEANQMSEEPKKGLNMELKVKNLASSDSRGYDLQKEVLVKVTHHGSHEVWIWSKAKFINRKFLMQELYQRFLDG----DHGPVARDDDPFWDPVEVVRLGSAHIWLQSLAYCMKLEEQVEFLNCDGLEEAVLHTCIAPCSPTGQTHGEEDVVIDPLELLGKRMDFQIHIVRCLGVNWMKEDAKRGTQIGYRIYDLPNTIYTKPVWKSVNPQIEETVQFAALTASQEFLNYLRTNALIVDLWGLQEGCTELSCSQLGLMVTGEGHILVDTKKISTVKDISQAASNQIPELYLKLLKLEQETEPLRNINRALREENVLLKASLAKTASGQAPKPSNTLKISGMTAQLPSAGEMSQMCTQQAGSDRELAKALKVFYQSMNTARGQLFRLRRHQPPEVDQML--RPFIHQRSQMFKDLGDLRESSLWTLKMTLLL--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HQR7-1", "uniprot_id": "A0AC58HQR7_DANRE", "id": "A0AC58HQR7-1", "name": "Kinesin-like protein 6", "aln": "---MRAKASEMASKDCVKVAVRVRPFNKRERDAGSRCIISMTSN-SISIQDPRNSQNSRTFTFDYTYWSHSGFSRNKDGLFVPEETGGRYADQASVFLDLGQGILDNALQGYNATLLAYGQTGSGKSYSMVGYGPNKGLIPTLCQRLFQSIRSMQDSRQCQVFFSMLEIYNEQVVDLLSKSSRSAGGLRVREDQQTGFYVEGLRRVPCDSALQVEQLMEQGTRTRTTAATHINNSSSRSHMLIIVQLKQIFSKECITKQSNIYLVDLAGSERQRSSGSEGDRLKEGTAINLSLTTLGNVISALADMALGKKIY-IPYRDSVLTKLLQSALGGNSRTVMIATLSPADICYEESLSTLRYAERAKKIQNKAVVNESPTERLVKELKAENAKLLLRLSRLGQEGRKAEDESKELRRLLTHNELQIRAIQTLWEQHLQEALKDWETQYATITQERRMMQMYPYIMNVNEDAQLSSVVKLFIQEEGEWDIGLADNSPRALSIRGLGIQEKHAVFSNQQRRVSITPVSGAKVIVNGLQVSKRTELQHLDRLVLGSNSTYLFIGFPSERSAEDWSRYDYDYFQSELAAAEGFHIQSLCDDQGHRPHQPDPSLLAVFYDYIKLMPMVTEANQMSAELKKGVEFKLEIKNLAMSDSKGHDLEKDIAVKVTSVESKQVWMWSKAKFINRKFLMEEVYQQQVAGGEGADRAPLPRDRDPFWDPLEPLHLGSAHLWLQSLAFRIPLEEQVEMVGPEGTEEAILQAQLVPCSPAGLALGEDDILIDPSELLGKRLDFQLVLDQCCGLRWVKEARNRGVQIGFQVFDCPQPLYTPAVWHNVNPLLDHRVQFTALRTSQDLLNYLQSNALVLELWGLQEGCSELLSNMDGMKMTQEDSVIIDKISASEHLT----AETGSSDLSSSLRALHQDLDKLRNANAALKKENSALREQLNSSRNG----------------VENNRGRQERRGSLRPSCDAEFAKALKVFYHSMTSVRGQLQRLRRHKPSEEEDLLGLRLFVDEHTFLLKDFSEQLEQCVSTLKHDVAAIVRRKREKSGVWS-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.*: *******.:**:::**:*:*** : . : :**:: : :***** :****.**.:::**:::. :. ::*.* .** *:*:****.* :********************:*:* ::*:** :*:.**::*.. . : **:*******:* : ****: :: .****:****: **:****: ***:. *:*:*:***:: * **:*::* ******::* :::**:* . :**:*.* :**** ****:*********:**: :*****.**.***.*** *:***: **********************.::*::*********:********* :*::*:** * * * : :***: ** : *:::*:.**.**: *:* **: * .. : .* *.:*** * * : :*:::* ** ***: :: **:******::*****::*::***** .:** .*:***:** * ***** * . :..**:**.* **:****:* ****** * ***: ::*::**** ***:* **:*:: **** :::**:*************:*:**: : . . :.:: ******:* ::*****:***.**. : ******::. :* ***:*: :.**** * : **:* :*** ******:*** : :* *:.*:** .** *:*: ::* *:.:** .**:.*** ::. *:*:** .*:::*:** :***:::********: * . .: .* *. :::*. . * :.. .:* .* *.*: : **: * **: ** *: * .: .. . .: : :...* ::*:****** .* .**** ***: :*.* :::* * *:.::: ::**: : *..: .** : ", "identical_positions": 461, "similar_positions": 281, "identity": "43.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-531", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JVZ7-1", "uniprot_id": "A0A0G2JVZ7_RAT", "id": "A0A0G2JVZ7-1", "name": "", "aln": "----MREPRKGFRARLARVLTGLGGRRERKGKISKEARLQDRPWGGQSCPDLAQSQGSTNDVSLKVQTQSHSEWDLRVRSHGGLWTQRRLHTSGRRSEPLGRLQRPAVG----------------SACDLAGYDSMEHECPAGTGSTEAIGGPSHPSRPESASPSLKQGSPGAPCQHPQHGAPEVLLKPELPGNLEDAPLLPRPDSFLTAAGAKGKPDTSGSAQSEPEPLHTRLCVRRTRYHITVTLQGCG-------------------------------------PAPGEEGKEPARPAPHPCGPEESRGWQEPPQKLRPITGYPINPPGEPPPRVPQHQGSKAQQERRVGWEPGFPHSREPVHRVAGASRVLLEPNMEGTTGSSARAEARVVSATLTWRQRPPAQEESRHRFHKVSLVSGARTEAPQEDVFEHSFRRE-EVNGFVKKEEEIVNCQGPREESGPMNFQSHGPIFSKKYIPPPKEKRPTMRLQEAADWGDGG----PQAPRTEPPGMGSMARTELLVPLPGPREPSPHPNVGVTSG--GSRNREEWRVTRTVR-TTTTTVVGGHVDRQVSSSVSVGPSVSGEALPRGRN-----------------------VTRTIRAVVVSPRAEGSPSRSQALEVLSNLVPAERIPPASRIPRLTMFTSR-------------------------------------GSGLGGTVGNTLGPPPETSPAELKTESSAPAPVGVPEVAHPPQNIDIPAAQLIQDQGGVSDARTVESSRLQRTSSPVLFPN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QTSQSQDRAPSSPKPQPCASS--PAHSPEQPVAPARLKAQASPHVLP-SVKEKFAGLP---------------------------VAPVPPMTG-IEVTKPEAPPNPSSPRRKAVPSSQSPCAPASPKDKFVQGPENRPSSALTQEEVFPGPRVPAHSHSP-----------------------------------------------------------------------------------------------------------------------------------------KEVLQARGAPIPSSSMPTTAVQDAEGGPSIKKEVGQDPQNSP------------------------------------------------------PRSLPCKETVEGPTAPGPLTPKQDVLVQESPGNSLSSPTPEECFQSPAVPLAPPSSEAKKPLSLEGSQAPEPMKAEASTESQLIPDSTEGTVPSEPS--------------REEDEAALTADLEIFLDTLRSMEPPEILRTHRLPRAPRSSYLAMYATLPAIEEDQ-LGPCVLGPSPQEGPSLEEEEE-------ELENPYLSDDEKLQ--RRQEKAAPGPSLDPHPSRPAKVTCSPMEMMKKLVAGQ-------GPEPQPSNRPTSRLGGSLLFG----------------------------------------------------------------NLVPANKDASALEPLGTKLSALPPHGAPGVRKVPGQLPLLCSGGP-PPEKPAPIQP-----------------------PEGWSPALKTQGKLNTRPGKVILFSEPGCQGRGREVWEDVADASAWAS--VASIRVIRGCWILYEQPEFRGQKLLLPEGDVELRALASTWSLQ---------------------------------GIGSLKRAVRDYCTPRISLFSEEGLKGKPVTLMGDLKDSQGLERPLQVASATVTAGLWLLYPKPFFEDTPCILEPGEYPTLEAWGTSGLSVGSLKPMRLGCPSVEKPGEPKAVVYEAPDFQGQSWEVSGDIYNLQQPED-SQSPQLTSVGSLRILGGCWVGYEKEGFRGHQYLLEEGEYADWSHWGGYDELLTSLRVIRTDFGDPAVVLFEDMDFQG-----HRVEVSSALPDVELAQHGPNTQAIHVLSGVWVAYEQVGFSGEQYILEKGVYRNCDDWGSGNCALGSLQPVVQVGESDLHFVSKIQLFSGPNFLGDHISFEDDQASLPASFHPQSCRVHGGSWVLFEDKNFEADQHIVSEGEYPTLTAMGCLASTVLGSLRKIPLHFSEPSLSLFGLECFEGKEIELTGEVRSLQAEGFNNHVLSVRVQGGVWVVCEHSDFRGRQWLVGSCEITNWLTYSGTQRVGSLYPIKQRRAYFRLWNAALGGFLSVPDHVEDMKAGRVVVSEPRAGGSCIWYYEEGLLKNQVAPTMSLQVIGPPSPGSKVVLWAESRLPRQTWSISELGHICSQMFEGQILDVKGGRGYDRDHVVLWEPTKDRPSQIWTVHVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A2I3BQG2-1", "uniprot_id": "A0A2I3BQG2_MOUSE", "id": "A0A2I3BQG2-1", "name": "", "aln": "----MREQRRGFRARLAQVLTGLGGRRKRKGKISKEARLQDRPWGSQSCPDLAQGQGSTNDVSLKVQTQSHSEWDLRVRSHGGLWSQKRLHSSGRQTDPLGRLQRPAVG----------------SACDLAGYGSMEHECPALAGSAEAIGGPSHPSGPEPASPSLKQGWSGTPCQHSQHSA------PELPGNLEDAPLWPHPESFLTAARAKGKPDTPGPAEPEPEPVHTRLCVRRTRYHITVTLQGCG-------------------------------------RAPGEEGREPARPAPHPCGPEESRGWQEPPQELRPITGYPINPPGEPPLKAPQHQGSKVRQKLLVGWEPGIPHSREPVHRVT--------RKMEETAGSPARAEARVVSATLTWRQRPPVQEESRHRFHKVSLVSGARMEAPQ-DVFEHSFRRE-EVNGFVKKEEETVNCQGSGEEPGSTNFQSHGPIFSKKYIPPPKEKRPTVRVQEAADWGDGG----PQAPRTELPGMGSMARTELLVPLPGPREPSPHPHVGVASG--GSRNREEWRVTRTVRTTTTTTVVGGHVDRRVSSSVSVGPSMSGETLPRGRN-----------------------VTRTVRAVVVSPRAEGSPSRSQALEVLSNLMPAERIPPASRIPRLTMLTSR-------------------------------------GSGPGGTVGTTLGQPLEISTTELKNSISALAPVGVPAVDSPAQNIDIPVAHPIRDQGGVSDARTEESSRLQGASS-VLLLN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QTSQSQVPASSSPKPQTCAAS--LTQSPEQPVVPAHLEAQSTPHVLP-AVKEKFTGLS---------------------------TVPVPPTAK-GEVTVPEPPPSPSSPRRKAAPSSQSPCAPASPKSKFVPDPENVPSSALTQKEVYPCPSVPAHSHIP-----------------------------------------------------------------------------------------------------------------------------------------KEVLQAHGAPKTSSSRPTTVVQNAEGGPSIKKEVGQYPQNSPS-----------------------------------------------------PCSVPCKETVESPTFPAPLPPKQDEVVRDSPGNFLSSPTPKGSFQSP--PFAPSSSEAKESLSLEGSPASKPMGAEVSTGSQTIPDSTEGKVPSEPS--------------EEEDEAALTADLEIFLDTLRSMEPPEILRTHRLPRAPRSSYLAMYATLPAIEEDQ-LGPCVPGPGPQERPVLEEEEEEVEEEEEELENPYLSDDEKLR--RRQEKAGPRPSLGLHPPTPAKVTCSPMEMMKKLIAGQ-------GPEPQPSNRPTSRLGGSLLFG----------------------------------------------------------------NLVPANKDAPALEPLGTKLSALPPHGAPGVKKVPGQLPLLCSGRP-PPEKPAPIEP-----------------------PEGWSPAPKTQGKLNTRPGKVILFSEPGCRGRGREVWGDIADASAWDP--VASIRVIRGCWILYEQPEFRGQKLSLPEGDVELRALACAWSLQ---------------------------------GFGSLRRAVQDYCTPRISLFSEEGLKGKPVTLTGDLKDSQGLERPLQVASATVTAGLWLLYPKPFFEDTPYILEPGEYPTLEAWGTSGPSVGSLKPMRLGCPSVEKPGEPKAVVYEAPGFQGQSWEVSRDIYNLQQPED-SQSPQLTSVGSLRILGGCWVGYEKEGFRGHQYLLEEGEYADWSNWGGYDELLTSLRVIRTDFGDPAVVLFEDMDFQG-----HRVEVSSALPDVELAQHGPSTQAIHVLSGVWVAYERVGFSGEQFILEKGVYRNCDDWGSGNCALGSLQPVVQVGESDLHFVTKIQLFSGPNFLGDHISFEDDQASLPASFHPQSCRVHGGSWVLFEDKNFEADQHIVSEGEFPTLTAMGCLASTVLGSLRKVPLHFSEPSLSLFGLECFEGKEIELTGEVRSLQAEGFNNHVLSVRVKGGVWVVCEHSDFRGRQWLVGSCEITNWLTYSGTQRVGSLYPIKQRRAYFRLWNAALGGFLSVPDHVEDMKAGRVVVSEPQAGGSCIWYYEDGLLKNQMAPTMSLQVIGPPSPGSKVVLWAESRLPRQTWSINELGHICSQMFEGQILDVKGGRGYDRDHVVLWEPTKDRLSQIWTVHVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N1P7-1", "uniprot_id": "CRBG2_HUMAN", "id": "Q8N1P7-1", "name": "Beta/gamma crystallin domain-containing protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEAGGPMARAKARVVSATLTWRQRPPTQEEIKHGFHKVSLVSGAQMEAPQKEMFEFSRREEVEVNGFATQEEETVNCQGPRDTAGSKNFQSHGPIFSKKYIPPPKEKRPEGRLKEAVDQSDGS----RQAPRTEPPCVGAMARTELLVPLPGPREPSPHPGVGLTSG--SSRSLEEYRVTRTVR---TTTVVGGHVDRRMSSSVTVRPVSSGEALPRGRQ-----------------------VSRMVPPVVVGS-PPGSPSRSQAVKVLSNLVPAGHSPPASHLPRPTAGGPR-------------------------------------STGLGSTVGAALRQLPETGTAELK-DSSALASTGIPASAHLPKNQDAPAACPDRDQGRAPDARACELWQVLGAPSSTELPL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QTSQGQASVPSSPRLETHVPSPGLTHPAKQPVVPTHPGARLTPLVLPPKKKDGPVDPP---------------------------AATVLPMVRSEHVTVPGQPPAPSTTRRKDVPSPGGLSAPSSPRNKFVQNSENVPVLPFTQREVVKGPGAPAASSPTRKEVVQGSSASAASSPTWKEVVKGPGAPAASSPTQKEVVQGSSAPAALFPTWKEVVKGPGAPDASFPTWKEVVKGPGAPAASSPTQKEVVQGSGAPAALSTTPKEVVKGPGAPAASSPTQKEVVKGPCAPAASSPTQKEVVQGSGAPAALSPKSTEVVQGPKGSSSIQKEAVQGIAGSL------------------------------------------------------APPLTKEETVQGPIAPATSLPKQDKGVQDSEGSPISSLTQKEVVQDPDALPAPSSSVDRVSPSPGGTPAPVPTGAEASTESQLVSDPTEGKTCTETS--------------REEDEVALAADLEIFLDTLRSMEPPEILRTHRLPRAPRSSYLSMYATLPAIEEDQ-LGPWVLGPGPQEVPSLEEKEEE---EEEEPENPYLSDDEKLQ--RRQEKAGPSPSRDLHPARPTQVSCSPLEMMKKHVAGTKGPHSELGLELQGGSRPTSRLGGSLLFG----------------------------------------------------------------SLVPTAKEASTPEPLGTKLSALLPHGAPGLRKVPGQLPLLCSERSSPTEKLACSLP-----------------------LEGWSPALKTQGKLNTRPGKVIFFSESGCQGSGREVWGDIVDASGWAP--VASIRVVRGCWVLYEEPEFRGQKLVLPEGDMELRTPGTKWSPQ---------------------------------GIGSLRRVVWDYSTPEISLFSEEGLKGEQVKLTEALKNSQGLEKPLQVASATVSAGLWLLYPKPLFEDTPYILEPGEYPTSEAWGTSDPSVGSLKPMRLGCPSVEKPGEPRAVVYEAPGFQGRSWEVSRDIYNLQQPED-SQSPHLASVGSLRVLGGCWVGYEKEGFRGHQYLLEEGEYPDWSHWGGYDELLTSLRVIRTDFGDPAVVLFEAMDFEG-----HGVEVSKALPDVELVQHGPSTQAIHVLSGVWVAYQEVGFSGEQYVLEKGVYRNCEDWGAGNSTLASLQPVLQVGEHDLHFVSKIQLFSRPDFLGDHFSFEDDQAALPASFRPQSCRVHGGSWILFDETNFEGDQHILSEGEFPTLTAMGCLASTVLGSLQKVSLHFSEPSIFLYGLECFEGKEIELSREVRSLQAEGFNNHVLSVRIKGGIWVLCEHSDFRGRQWLVGSCEITNWLTYSGTQRVGSLYPIKQRRVYFRLWNAALGGFLAVPDHVEDMKAGRVVVADPQAGGSCIWYYEDGLLKNQMAPTMSLQVIGPPSPGSKVVLWAESRLPRQTWSISESGHICSQMFEGQILDVKGGRGYDRDHVVLWEPDEDRASQIWTIHVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AL91-1", "uniprot_id": "A0A8M3AL91_DANRE", "id": "A0A8M3AL91-1", "name": "", "aln": "MEKKSSSSRRTLKSLFSRSEVNLSEHEPKTDSNGGSFRLFKWKKKKKSESSEDNPNTDRAESADGDIQDGEEQNKHKTALFGRSKKGKRSYSETDLHKPKGFIGSLTWGRKKKQNRDRVQDLTSNSDISGVKDHISEQEEFDNHKETEQIQACVEAVRSAPEPPCASDQSQSQHVLSDQSTLSEEDAGFMPTAQESKAIPYIDSSDSDAYQTPPDSPNISSDAQAQPDTQYGKLSAQNSITSETSEYYICPGTDMKTAACTDTSTARISHDNVVSQKRSHLEHGEYSNAASLTQESYISRPESTDSSIHESSSLFIPKSPVFSIPESSFSSDPQNPTASIPQVSSSSDPQLSTSSIPESSFSSGPQISTSSIPQSTSTSVPQISTSSIPQSASTSVSQISTSSVPDSSSVSVPQIFISSVPQSSSSSDPQISTSLIPEFSSSSDPQIFTSSILQSTSTSVPQISTSSIPQSSSSSVPQISTSSIHQSSPTSVPQMSTSSIPQGSSSSVPQISTSSIPQSSSSSVPQISTSSIPQSSPTSVPQISTSSIPQGSSSSVPQISISSIPQSSTNSVPHSSTPLVHESSSSYIPQSSTSTMHDSFNSDSTMTQSFSTNTNSAFNLPEDSFSHPADTISYEDSHTTSANVRNKSFIDSNVINSDPSSPTTDICESDHVSSKPYVIVSSTLCSSRIKGNRIKTDRKPSSSNTNVSESDVTVHSTADSGSREETPPESSCVTISKESHATDNYSSLAYATDSEKHNPAQPVLPENESNIPLSPSARAYTIIKSTKVVTFDLSGPSDHISFDHSHRSLSNNEPDSDVETLTEILDHEGQDNNQTDTDSSAKASSGFPNHTIPSMSLTSYPPLHLDVSDQMFSSQSLKAKTEKQQKTSRACEDQEKCLQDASITEDTKLQKVSEECGMLKKKEDDVLIETEKQQKTFRACEDQEEYPQHASTQSLDPVDRINQNKSNAEITEATTLHKALEKVAMVEEKRDELYTKMEKQQKTFRAYEDQEGYLQDASTQRFTEKSIGESETNAERMTTTDDATSVTEDTKLQKVSEEFAMVKKKEDDVLMETEKQQKTFRAYKDHEEHLKDISAHRFIEKSVDQDKSNAEIKVSTKLHKALEKFAMVEKQRDDLHEETEKQQKTSRTYEDREACLQDASTQRFIEKSVDQNESNAEITEATKPHKALEKVAMVEKKTDELHMGTEQLKTSRAYEDREEYAQDASTQRLESIDQINQNKSNAERTTTRNDAISILDNELNQIIEATKLHKASEDSPMLKKMSNESHMDQISSAVETEACRGAGVLTGQAEPQIPSLSTPKPAIPVHQEHVPEECTPAPPFSELLKVSLTDSSMQSQSHLENLPLPLGLHQYNTEITILEDTAGCKHHSSTDKNTHGGYIDTLSRTLGSESQDCSIEELSGAYSTKQTFTHSNDSKQEEVKADGDTISLWNQISESTSDTERKEETDDLADQTASDCLTPGERIVHATVPSTVIEHNQVLNTVMNSGVSVLNTKLNPPSSPRDGRDDGVVFRKVSLVKNELPEPSRASPELQRRFQALQDKTERSDYTHSYEKAVYTSHFHSPETEVTHYSGGRGREELSLPGERLQIIPTHSQLDPEPALFIVEADDSEVFQAMRVELHHSPTSTEPPLLNSEMDNLVDTLKSMDRPLRQRVQRAPSN------APFSSLPPIEEDAPVSPSITPLSPPFSPVHEPKSMLNGSSGLDFGFNWSSTKDMRSPLTMMKEQQFGDAQNRGLSLPLRASALSSIVMRRSSLNDLSPEDGSAKPLINGASSSSRLENSFFFQPSENGASSRSIFRAASLPDIGSGADRISSAAKSTDSLVGSRFERFSYLTSPSNSLSGIAEASRISVAPFAQSQSAESQSFSHKSTSELYRSLPSETLLKSPPSLSIQRSSSLDGGFLINDNLQVNQKPEPEPERNLLLKYRAFPDAYLTKEKEHGKLNPRPGKMIIYDKPGFTGERIEVRGDVVDATPWEFTDTISVRVIRGGWVFYEKPDFKGEKIALDEGEMELTDPFRPAEEEEEADLQNGGESHGEIVNDGEEQQENKPHRTRKFSIGSIRRAVRDYSVPEISLFPEENAEGKKVTFRDTSEDARIFGFPIKANSIIINAGLWLVFAEPFFQGVPRVLEVGGFPSPSAWGVTHPYVGSLHPLKIGEPRVENLYEPRLVLYEKPYFTGKSREIYSSMRDFLSRADKQQTLFMFSAGSLKVTGGCWVGYEKEGFRGNQYLLEEGEYHDWRVWGGVNSELRSVRVIQSDLSEPQLVLFAMPEQESEQDEERTFDVTEAVADVELFGFGINTRSIQVLSGAWVAYSHVDFSGNQYVLEKGFYNNCGDWGSGDNRICSLQPILTAPSDGPILRNEVLLYSEPDFLGSCRVCHHNQDALPESLMVRSCRVVGGSWVLYGEEKFSGSMYVLSEGDYPNLSSMGLPADSRVRSVRAVPVSFCVPSVSLFGLECFEGREVTIDTQISSMQEEGFNTQFLSVRVNTGCWVLCEHSNYRGRQFLLEPIEITNWLKFSSMSCIGSLYPVRQKQRPFRIRNKQTGHCVSVQGGVEDMKTGRVLVSEQVEGMSDIWLYQDGLIKNKLARSMSLQVMGNVESGAKVVLWTETRVPVQTWSAQMSGAIASLTFPGMVLDIKGGKTYDKEHLVIREENEEQPSQQWELEFV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .. .:: : ** * . . . : * . *.: :. : . . : : *... : .. . . ... .* ..: . . . :.. . .: . :*. * . :. * .: : .:: .. .*:. * :. :* .* . :: *.:* . . .** : * * .:: . : .:: .: *.. : : **:: : .*:: : . .: . * * . . :. . * . .:: : . . .::. . : : . : :.. . : :*.: * : :. . : ::.* . *. : . * : . ... .:. . ::.*.. . . *: .*: * ..* .* . . :* ::. * . . : ....: . .. . * .. .: :* : . . : : .: . : : . . : . . .* ** .:.: . :: * . : * :::: ::***:**: * *.:* * : :::**.**** :.* : .* * * :. : : * .: :: : . . * :.:. . :*:: . . . .:*** .*::* .:.* :. .: . :: *: : : ..: . * *. . . : :.: . * :****.****:*::.:.* * ** *:.**: * . *:**:** *::**:*:*:*:*: * **::** . : .:**::*.* **..*.****.**. :*: *.: :::: : *::. * :.*****::.:*:*:..* :** * :*: .***.: ****:*:::* * **: **: *:** * * *:* *: .: :: . * .*: : *.***:: **************:********* ** *** :. * *:***::*:.:* :*** : :. : .:*:.*:.**** .* .*::*:****.****..*.***:*::****.*.** ***:*: : ****:: . . . : .:: *:* *:***. ..:* :** *: :**** ****:*: : :*... :::***::*.*::** *.: : *:: :.: *. **: *:*******:*: : :: *:* ****.:.****:: * **:****::****:*: . ******.:*. . :*****::*:: **: * * ::* . *****:***:*:: * * ** *::**:**::* :*****:* ..*:*****:*:*:* **** . * *.* * * :**:***: **::*:*: * ::: ** * :..:", "identical_positions": 382, "similar_positions": 510, "identity": "14.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-532", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q09019-1", "uniprot_id": "DMWD_HUMAN", "id": "Q09019-1", "name": "Dystrophia myotonica WD repeat-containing protein", "aln": "MAAGGAEGGSGPGAAMGDCAEIKSQFRTREGFYKLLPGDGAARRS--GPASAQTP--------VPPQPPQPPPGPASASGPGAAGPAS---SPPPAGPGPGPALPAVRLSLVRLGEPDSA----------------------------------GAGEPPATPAGLGSGGDRVCFNLGRELYFYPGCCRRGSQRSIDLNKPIDKRIYKGTQ-----------PTCHDFNQFTAATETISLLVGFSAGQVQYLDLIK--KDTSKLFNEERLIDKTKVTYLKWLPESESLFLASHASGHLY--------LYNVSHPCASAPPQYSLLKQGEGFSVYAAKSKAPRNPLAKWAVGEG--PLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDPYTT--RAEEAATAAGADGER-----------------SGEEEEEEPEAAGTGSAGGAPLSPLPKAGS------ITYRFGSAGQDTQFCLWDLTEDVLYPHPPLAR----------------------------------------------------------------------------TRTLPGTPG-----TTPPAASSSRGGEPG---------PGPLPRSLSRSNSLPHP------------AGGG-----------------KAGGPGVAAEPG--------TPFSIGRFATLTLQERR-DR---GAEKEHKRY-----------------------------------------------------HSLG--NISRGGSGGSGSGGEKPSGPVPRS-----RLDPAKVLGTALCPRIHEVPLLEPLVCKKIAQERLTVLLFLEDCIITACQEGLICTWARPGKAFTDEETEAQTGEGSWPRSPSKSVVEGISSQPGNSPSGTVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08274-1", "uniprot_id": "DMWD_MOUSE", "id": "Q08274-1", "name": "Dystrophia myotonica WD repeat-containing protein", "aln": "MAAGGAEGGPGPSAAMGDCAEIKSQFRTREGFYKLLPGD-ATRRS--GPTSAQTP--------APPQPTQPPPGPAAASGPGAAGPAS---SPPPAGPGPGPALPAVRLSLVRLGDPD------------------------------------GAGEPPSTPSGLGAGGDRVCFNLGRELYFYPGCCRSGSQRSIDLNKPIDKRIYKGTQ-----------PTCHDFNQFTAATETISLLVGFSAGQVQYLDLIK--KDTSKLFNEERLIDKTKVTYLKWLPESESLFLASHASGHLY--------LYNVSHPCTSTPPQYSLLKQGEGFAVYAAKSKAPRNPLAKWAVGEG--PLNEFAFSPDGRHLACVSQDGCLRVFHFDSMLLRGLMKSYFGGLLCVCWSPDGRYVVTGGEDDLVTVWSFTEGRVVARGHGHKSWVNAVAFDPYTT--RAEEAASAS-ADGDP-----------------SGEEEEPEVTSSDTG----APVSPLPKAGS------ITYRFGSAGQDTQFCLWDLTEDVLSPHPSLAR----------------------------------------------------------------------------TRTLPGTPG-----ATPPASGSSRAGETG---------AGPLPRSLSRSNSLPHP------------AGGG-----------------KAGGPSASMEPG--------IPFSIGRFATLTLQERR-DR---GAEKEHKRY-----------------------------------------------------HSLG--NISRGGSGGNSSN-DKLSGPAPRS-----RLDPAKVLGTALCPRIHEVPLLEPLVCKKIAQERLTVLLFLEDCIITACQEGLICTWARPGKAFTDEETEAQAGQASWPRSPSKSVVEGISSQPGSSPSGTVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3B1E4-1", "uniprot_id": "A0A8M3B1E4_DANRE", "id": "A0A8M3B1E4-1", "name": "", "aln": "MAADGG--------ALKDINEIKSQFRTREGFYKLLTLSDSQQRA--GLPRGPTG--------VTAG-AGSIPGGAAGVGGLVQGPG------AAANSSPG-FLPPVRVSMVKLKPED-----------------------------------------PSEES------ERVCFNIGRELYFYT---YTNIKKAVDLSKPIDKRIYKGTQ-----------PTCHDFNQFSATADSVALIVGFSAGQVQYLDPIK--KETSKLFNEERLIDKSKVTCLKWLPKSENLFLASHASGHLY--------LYNVEHPCGTTAPQYCLLRQGEGFSVYSCKTKTPRNPLLRWVVGEG--GLNEFAFSPDGVHVACVGQDGCLRVFHFDSMELQGVMKSYFGGLLCVSWSPDGKYLATGGEDDLVTVWSFSESRVVARGHGHKSWVNVVAFDPFTTNLEDEEPMELSGSDEDL-----------------QQGALHFGRVRTSSTLSRLSRHSSKGGAAS------VSYRFGSVGQDTQFCLWDLTDDVLYPRLPLSR----------------------------------------------------------------------------ALTNTFGPT-----VATSNSGSVVEGHHHPSIQTASTLPLPLPRSLSRSNSLPHP------------AVAN-----------------TSKSQGAPESTGTVSSSGTVTPFSIGRFATLSLQERKSDKSGVGGEKEHKRY-----------------------------------------------------HSLG--NISKSN--------DKINVAPRSS-----RLDGAKVLGTTLCPRMNEVPLLEPLVCKKIAHERLTVLVFMNDCIITACQEGLICTWARPGKTHASQP---------------------LSAQNGNSPSGTVV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBC4-1", "uniprot_id": "WDR20_DROME", "id": "Q9VBC4-1", "name": "WD repeat-containing protein 20 homolog", "aln": "MANQLD---------ASVKDDLKTQFVTREGTYRLLTLSEYSRPNRVGYSSNQSSPQVRVSMVTLPSPAQGKLGSDVGVGTPVGGGTAGANTTTTNGSSPGASPTGAAGASTAISNGGAGGDYSHSNHNSNSAGNNTVEARLGGGISMHSMMNGGVVDQNGVATNQVLGGDRICFNFGRDLYVYS---FRGAKKGTEMSKPIDKKFYKGTN-----------PSCHDFNISSATPTGAPLLVGFTTGQIQLVSPHVGPREVRKLFNEERLIDKTKVTCLKWLPNSPHLFLAAHASGHLY--------LYNEELPCAATAPSYQPFKLGDGYTILTSKSKTTRNPLFKWVFSTDNCCVNEFCFSPCGSHLAVVSQDGFLRVFHYDTMELLGIARSYFGGFLCVCWSPDGKYIVVGGEDDLVTVWSLHERRVVARGQGHRSWVSVVAFDPYTTSYTNWDGGDFSDDENQMNEYSHSREARFSGDSTANGGFEGFDRNSTPVHADRNGPHSASFRSDASSAEKLMSYRLGSVSQDTQICLWDITEDVLRHPLVLRQPANSERAYLNGGVDEEAEAEDGIKVIRPVAMSGQATGQQAESGSCSPTREAAGGGTGNGAGEHSNSSSSKFSTANCTISSQSSPDDCDTEAATPASTSSNAGAGSVAGAGAVASTKQNNRNHGTGNSIKFPNCISATKSDSIDGGGGSGSGQRPSQTTSGYNSKTSNSSNKSSNSGSGFSAFNSLTQRLSNFSFLSSSEKKGAGYEGSHSTAHRQHRKAMSMLKSYNQHNHTGGHNNHSQSNNSSSSNFGHSSTLDSNAAGAIGSSSTAHSFGSLKLSRSSHHSSLATAAHASGSAAGSGSGVSSFDPMQLIGTPACPRFDECPLLEPLVCKKIAHERLTALIFREDCFLTACQDGFIYTWARPGHATHATQH--------------------LSPGQAAAPGGTVI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8I6ANX6-1", "uniprot_id": "A0A8I6ANX6_RAT", "id": "A0A8I6ANX6-1", "name": "Myotonin-protein kinase", "aln": "MSAEVRLRQLQQLVLDPGFLGLEPLLDLLLGVHQELGASHLAQDKYVADFLQWVEP-------IAARLKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVS--------------------------------CFREERDVLVKGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIVMAIDSVHRLGYVHRDIKPDNILLDR-CGHIRLADFGS----CLKLQPDGTVRSLVAVGTPDYLSPEILQAVGGGPGAGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYAKIVHYREHLSLPRADMGVPEEAQDLIRGLLCPAEIRLGRGGAGDFQKHPFFFGLDWEGLRDSVPP--FTPDFEGATDTCNFDVVEDRLTAMVSGGGETLSDMQEDMALGVHLPFVGYSYSCMASRDNQVTDPTPMEL---------------EALQLPVSDLQGLDLPPPVSPPDQAAEEADP------AAVPVPPAETETMVTLRELQEALEEEVLTRQS---------------------------------------------------------------------------LSRELEAIRT-----ANQNFSSQLQEAEVR-----NRDLEAHVRQLQERMEMLQAP------------GAAG-------------------ESLTHSQPGG--------RRVEMGHVGCMNPGAGEESRLGHRSRATALLR------------------------------------------------------PPRSIHLSLLLPAVTGVPSPRATDPPSHMAPRPWLWASARWWGQAPCTAVTCCSLPG---SLGLAYPRRIACSCSPLLWLLPPHWAALGWWPIPAVSPQSGVS----------------------REPPSPPEP---", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ::. : * :: * . : . . . * .* . : . :: * : : *.* : . :.::: : * :. :::. *::: . ** : : . * .:*. . :.. ... * * . : .: :: : * . : . :.* ::. . .. : .: : *: * : :. . :* :*. ..:: : . : :.* :: : .. : . : . .. :* . * :: : : : . : . . : : : * . .. . . * :.... :. . . ::* : . . : * . *. . .* . :* * . : . : . : *. *. : .* ", "identical_positions": 36, "similar_positions": 152, "identity": "3.75%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-533", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q59EK9-1", "uniprot_id": "RUN3A_HUMAN", "id": "Q59EK9-1", "name": "RUN domain-containing protein 3A", "aln": "MEASFVQTTMALGLSSKKASSRNVAVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFVNFAAILEQILSHRFKACAPAGPVSWFSSDGQRGFWDYIRLACSKVPNNCVSSIENMENISTARAKGRAWIRVALMEKRMSEYITTALRDTRTTRRFYDSGAIMLRDEATILTGMLIGLSAIDFSFCLKGEVLDGKTPVVIDYTPYLKFTQSYDYLTDEEERHSAESSTSEDNSPEHPYLPLVTDEDSWYSKWHKMEQKFRIVYAQKGYLEELVRLRESQLKDLEAENRRLQLQLEEAAAQNQREKRELEGVILELQEQLTGLIPSDHAPLAQGSKELTTPLVNQWPSLGTLNGAEGASNSKLYRRHSFMSTEPLSAEASLSSDSQRLGEGTRDEEPWGPIGKDPTPSMLGLCGSLASIPSCKSLASFKSNECLVSDSPEGSPALSPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QCE8-1", "uniprot_id": "F1QCE8_DANRE", "id": "F1QCE8-1", "name": "RUN domain-containing protein 3A", "aln": "---------MAMGLTSKKTSSRNIGVERKNLITVCRFSVKTLLEKYTAEPIDDSSEEFINFAAILEHILSHRFK-----GPGGWFSSDGQRSFWDYIRLACSKVYNNCISSIESIENISTSRAKGRAWIRVALMEKRLSEYVAIALRDTRTTRRFYDDGAVMLREEATVLTGMLIGLSAIDFSFCLKGEVLDGKTPAVIDYTPYLKFTQSYDYLSDEEDRRSVDSSASDESVAEHPYIPLVTDEETWSNKCRKMEQRFKIVNAQKGYLEELVRLRESQLKNVETENKRLDAKLEELQVQSQQEKKELEAIILELQAQITGIIPCEPSHLVKG---LSIPLINQWATAQATN---NQGNVKLFRRRSFHSLD-LSADLSLNSDSQKE-DGNQNGDTVWSAAKDNTPSMLGLCGSLASLPSCKSLASLKSSEYLVNISTEPSPALSPS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:**:***:****:.*********************************:*******:******* ** .********.************ ***:****.:*****:****************:***:: *************.**:***:***:***************************.*****************:***:*:*.:**:*::. .****:******::* .* :****:*:** ******************::*:**:**: :*** .*.*:**:***.:***** *:**:**.: : *.:* *: **:***.: : * . .* **:**:** * : ***: **.****: :*.:: :. . .** *************:********:**.* **. *.* *******", "identical_positions": 310, "similar_positions": 83, "identity": "69.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-542", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61187-1", "uniprot_id": "TS101_MOUSE", "id": "Q61187-1", "name": "Tumor susceptibility gene 101 protein", "aln": "-MAVSESQLKKMMSK-YKYRDLTVRQTVNVIAMYKDLKPVLDSYVFNDGSSRELVNLTGTIPVRYRGNIYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHDWKHPRSELLELIQIMIVIFGEEPPVFSRPTVSASYPPYTATGPPNTSYMPGMPSGISAYPSGYPPNPSGYPGCPYPPAGP-YPATT-SSQYPSQPPVTTVGPSRDGTISEDTIRASLISAVSDKLRWRMKEEMDGAQAELNALKRTEEDLKKGHQKLEEMVTRLDQEVAEVDKNIELLKKKDEELSSALEKMENQSENNDIDEVIIPTAPLYKQILNLYAEENAIEDTIFYLGEALRRGVIDLDVFLKHVRLLSRKQFQLRALMQKARKTAGLSDLY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99816-1", "uniprot_id": "TS101_HUMAN", "id": "Q99816-1", "name": "Tumor susceptibility gene 101 protein", "aln": "-MAVSESQLKKMVSK-YKYRDLTVRETVNVITLYKDLKPVLDSYVFNDGSSRELMNLTGTIPVPYRGNTYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHEWKHPQSDLLGLIQVMIVVFGDEPPVFSRP-ISASYPPYQATGPPNTSYMPGMPGGISPYPSGYPPNPSGYPGCPYPPGGP-YPATT-SSQYPSQPPVTTVGPSRDGTISEDTIRASLISAVSDKLRWRMKEEMDRAQAELNALKRTEEDLKKGHQKLEEMVTRLDQEVAEVDKNIELLKKKDEELSSALEKMENQSENNDIDEVIIPTAPLYKQILNLYAEENAIEDTIFYLGEALRRGVIDLDVFLKHVRLLSRKQFQLRALMQKARKTAGLSDLY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F4Y8-1", "uniprot_id": "E7F4Y8_DANRE", "id": "E7F4Y8-1", "name": "", "aln": "MSAINESSLRKVFSKYYKYRDLTARDITNVTNIYKDLKPMMDNYVFNDGSTKELLSLTGTVPVNYRGNIYNIPVCLWLLDTYPYNPPICFVKPTSAMMIKPGKHVDANGKVYLPYLHEWKPPQSDLYGLIQVMIVVFGEEPPVFSRPSSQPAYPAFPAAGPPNTSYMP-TPQGL-PYSQGHSANPGVFQGYPYPATGSGYPTTSGSSMYTPMSSVPTVGPSRDGTIGEDTIRASLVSAVSDKLRRRMKEEMDGAQAELDALRRTEEDLKRGHQKLEEMVTKLDVEMAEVDRNIDRLKQKDEELTAALERMENQAEDNDIDDVIVPTAPLYKQILNLYAEENAIEDTIFYLGEALRRDVIDLDVFLKHVRLLSRKQFQLRALMQKARKIAGLSDLY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:.**.*:*:.** *******.*: .** :******::*.*******::**:.****:** **** ****:*********************:* **.*********:******:** *:*:* ***:***:**:******** ..:**.: *:********* * *: .*..*:..**. : * ***. *. **:*: ** *.. ..*.**********.********:******** ******* *****:**:*******:**********:** *:****:**: **:*****::***:****:*:****:**:********************************.****************************** *******", "identical_positions": 293, "similar_positions": 70, "identity": "74.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-546", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LRY6-1", "uniprot_id": "A0ABK0LRY6_RAT", "id": "A0ABK0LRY6-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------MIFPD----------------------------------------YFDWDKYLKETGSVSAPSEYFRQAKTPPTNEFQIGMKLEARDPRNIDSVCVASVIGITGARLRLRLDGGDNKNDFWRLVDSSDIQPVGTCEQEGDLLQPPLGYRMNASSWPMFLLRVLTGSELAPAVFFKKEPPRPPQNNFIVGMKIEAIDRKNPFMICPATIGAVSGDQVHITFDGWSGAFDYWCSYDSRDIFPVGWCRLTGDILQPPGKIRKLIPNYMFCHFRSDFDNVVFN---SIEAAEKTMSSVFTD-----------------------TLEDEDRTLKDFQAAPGWKKPKGRGFIKPGIDEARPGKHDQGAPAGKKSKGRGFTKTWEGETRPGRVVQVVPG--------------ECFFMFIS----------------------------------EKKRRGKTVTTPWSDQPRLFADQQAAPAEKKRKGKTVTTPWGDQPRLFTDPGAAPAEKKRKGKTITTPWTGQPRHFADQGTAPAEKKRKGKTITTPWSDQPRLFADQGAAPAEKKRKGTTVTTPWSDQPRLFADQGAAPAEKKRKGKTVTTPWGNQPRLFADQGAAPAEAKPKGRRVTKPRKDQDQFLADEEAMPALFSALSVSSTEKTPPSSSEQPKSSTSGKPKSSAFGKPKSSTSKGTQPSRKSPRKTS----VPKTSKKAGKTKSAGD-----TSASKKGITIKIVLP--KKRAGRNGKKEKIIPVVSSTSSASLSSLMRSS--SSNKTPE-----EPSKIVMSTVCVYINKHGDCGPYLDPQKVRQLPNHFGPGPVNVILRRTVQACVDCAIQPKDVFLFLKPDNRGGEMITAFFDGKVHTVQLPPVNSASFALRFLENFCRNLHCDKFLSSQPFRLKTHVHTSATNIDQSKPEN--EEPKG-KRSFKRLSSQPQP-SAPVSSKVPR---------------------------------KSG---------------------------------------------------RASKASSYIAVPDPSVLKQGFC----KDPSTWSVDEVIQFMKHTDPHISGPLADLFRQHVTY----LLIR---------------FSCCPNASK------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AVB3-1", "uniprot_id": "B1AVB3_MOUSE", "id": "B1AVB3-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------MGQTANED----------------------------------------HFDWDKYLKETGSISAPSEYFRQSKTPPTNEFKIGMKLEARDPRNIDSVCVASVIGITGARLRLRLDGSDNKNDFWRLVDSSDIQPVGTCEQGGDLLQPPLGYTLNTSSWPMFLLRVLTGSELAPAVFFKEEPPRPLQNNFIVGMKIEAVDRKNPFMICPATIGAVCGDQLHITFDGWSGAFDYWCDYDSRDIFPVGWCRLTGDVLQPPGKIVEKRPRRKRRTRLWRLRTALLGNEEEAPAAEEPGTSVLTFGDENRTLKDCRGEAAEEPGTSAFTFGDENRTLKDCQG--GWKKPKGRGFIKPGKDETRPGKHDQGAPAGKKPRGRGFTQPLEDEARPGRDVQVAPAEKKRKGKTVTTPWTEDPRLFADQGDAPAEKKRKGKTVTTPWTEDPRLFADQGDAPAEKKRKGKTVTTPWTEDPRLFADQGAAPAEKKRKGKTVTTPWTEDPRLFADQGDAPAEKKRKGKTVTTPWTEDPRLFADQGDAPAEKKRKGKTVTTPWTEDPRLFADQGAAPAEKKRKGKTVTTPWTEDPRLFADQGDAPAEKKRKGKTVTTPWTEDPRLFADQGDAPAEKKPKGKRVTKSRKDQAQFLADEEAMPALFSALSVSSTERTPPSSSEQPKSSTSGKTKS---------TSRGAQTSRKSPRKTSVVQPVPKTSKKAGKSKSTGN-----TSSPKKGITIKIVLP--KKKGGKSGKKEKSIPVISSTSSASLSTLMKSS--SSNKTSA-----GPSKIVMSTVCVYINKHGDCGPFLDPQKVQQLPNHFGPGPVNVILQRTVQACVNCAFQAKDVFLFLKTDNRGGEMITAFFDGKVHTVQLPPVNSASFALRFLENFCQSLQCDNFLSSQPFRREAQVPTPDTGTDQSKPEN--GEPKE-KRSLKRLSLHPHR-SAPVSSKVPR---------------------------------KSG---------------------------------------------------QASKASSYITVPDPSVLKQGFC----KDPSTWSVDEVIQFMKHTDPQISGPLADLFRQHVTY----LLIR---------------FSCCPNASK------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQR0-1", "uniprot_id": "SCML2_HUMAN", "id": "Q9UQR0-1", "name": "Sex comb on midleg-like protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------MGQTVNEDSMDVKK-----------------ENQEKTPQSSTSSVQRDDFHWEEYLKETGSISAPSECFRQSQIPPVNDFKVGMKLEARDPRNATSVCIATVIGITGARLRLRLDGSDNRNDFWRLVDSPDIQPVGTCEKEGDLLQPPLGYQMNTSSWPMFLLKTLNGSEMASATLFKKEPPKPPLNNFKVGMKLEAIDKKNPYLICPATIGDVKGDEVHITFDGWSGAFDYWCKYDSRDIFPAGWCRLTGDVLQPPG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSVPIVKN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------IAKTESSP---------------------------SEASQHSMQSPQKTTLILPTQQVRRSS-RIKPPGP-----TAVPKRSSSVKNITP--RKKGPNSGKKEKPLPVICSTSAASLKSLTRDRGMLYKDVAS-----GPCKIVMSTVCVYVNKHGNFGPHLDPKRIQQLPDHFGPGPVNVVLRRIVQACVDCALETKTVFGYLKPDNRGGEVITASFDGETHSIQLPPVNSASFALRFLENFCHSLQCDNLLSSQPFSSSRGHTHSSAEHDKNQSAK--EDVTE-RQSTKRSPQQTVPYVVPLSPKLPKTKEYASEGEPLFAGGSAIPKEENLSEDSKSSSLNSGNYLNPACRNPMYIHTSVSQDFSRSVPGTTSSPLVGDISPKSSPHEVKFQMQRKSEAPSYIAVPDPSVLKQGFS----KDPSTWSVDEVIQFMKHTDPQISGPLADLFRQHEIDGKALFLLKSDVMMKYMGLKLGPALKLCYYIEKLKEGKYS-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B461-1", "uniprot_id": "A0A8M3B461_DANRE", "id": "A0A8M3B461-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------MGKTHQKDKKHHKE-----------------KSGRNNEDSQPSQKLTEAFSWEMYLRETSSCPASPSCFRQSRVPPANDFRVGMKVEACDPRNASSWCIATVMGLMGVRLRLRLDGSDSTNDFWRLVDAADIQPIGTCEKSGDMLQPPLGFRMNASSWPMFLLKTLSGAEMAPSSAFKKEPPRPTQNFFKAGMKLEAVDRKNPYLICPATIGEVRGDKIFIMFDGWRGAFDYWCQFDSRDIFPVGWCQLTNHSLQPPGN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CFTIPKTLLPSVSRPSP--------------------------------------------------------------------------------------------------------------------------------------------------------------------SWRPMQSPYRLPHPLPPLPVRKG----------------VRGRRPKSQTIAMLKAAAEAAAAGNSPSQNGQSQP-----TSAHKSPISSPLTPKPYKKRGPKPGSKRKPK-VPHSLSSPILSSSVSDGRLSSLQTTR-----DSG--VVSTVCVYVNKHGNSGPHLDRKLLLQLPDHFGPGPVNTVLQHAVQACVDCAFQPKALFSFLQSQSDGGEIIRVRSEGGIHYVKLPTASSASFVLRFLETLCHHLQCDNLFSSQPFSPLTSSTHTPYERSKSVKEETSEALSV-ARGTRRFNRDSSAYSTALSPKLQRTEALPSDETIAHAENGASTEQQFLEESMDSASKSVAP------RPPAHRSTSEFHTPTGSSPHYPSHPPLLRGLSSNPAEPRTHRRVEGRLSASSTTGPDHQATEKDPSKTSNKSPSSWSIEEVMQFVRDADPQALGPHAELFRKHEIDGKALMLLRSDMIMKYMGLKLGPALKLCHHIEKLKQTK-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8K214-1", "uniprot_id": "SCMH1_MOUSE", "id": "Q8K214-1", "name": "Polycomb protein SCMH1", "aln": "-------------------------------------------------------------------------------------------------------------------------MLVCYSVLACESLWDLP--------------------------CSIMGSPLGHFTWDKYLKETCSVPAPVHCFKQSYTPPSNEFKISMKLEAQDPRNTTSTCIATVVGLTGARLRLRLDGSDNKNDFWRLVDSSEIQPIGNCEKNGGMLQPPLGFRLNASSWPMFLLKTLNGAEMAPIKIFHKEPPSPSHNFFKMGMKLEAVDRKNPHFICPATIGEVRGAEVLVTFDGWRGAFDYWCRFDSRDIFPVGWCSLTGDNLQPPG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TKVVIPKNPSP----------------------------------------------------------------------------------------------------------------------------------------------------------------------SSDVSTEKPS---------------------------IHSTKTVLEHQPGQRGRKPGKKRGRTP-KILIPHP-----TSTPSKS-AEPLKFP--KKRGPKPGSKRKPRTLLSPPPTSPTTSTPEPDTSTVPQDAAT---VPSSAMQAPTVCIYLNKSGSTGPHLDKKKIQQLPDHFGPARASVVLQQAVQACIDCAYHQKTVFSFLKQG-HGGEVISAVFDREQHTLNLPAVNSITYVLRFLEKLCHNLRSDNLFGNQPFT-QTHLSLTATEYNHNHDRYLPGETFV-LGNSLARSLETHSDLMDSALKPAN---------------LVSTSQNLRTPGYRPLLPSCG------------------------LPLSTVSAVRRLCSKGVLKGKKERRDVESFWKLNHSPGSDRHLESRDPPRLSGRDPSSWTVEDVMQFVREADPQLG-SHADLFRKHEIDGKALLLLRSDMMMKYMGLKLGPALKLSFHIDRLKQVFWKRETILWSREGLSREVWPISEDTALGHFFSGMDKVFGSLSKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VHA0-1", "uniprot_id": "SCM_DROME", "id": "Q9VHA0-1", "name": "Polycomb protein Scm", "aln": "MSGGRDSSTSSGSNSAAPGASTNATSSASASASSTSTSASPGSTTSPASTQRQRGRPAKRATCTWCGEGKLPLQYVLPTQTGKKEFCSETCIAEFRKAYSKGACTQCDNVIRDGAPNKEFCSIMCMNKHQKKNCSTRHSGGSASGKGLAESERKLLASGAPAPTGPFQYESFHVFDWDAYLEETGSEAAPAKCFKQAQNPPNNDFKIGMKLEALDPRNVTSTCIATVVGVLGSRLRLRLDGSDSQNDFWRLVDSTEIHAIGHCEKNGGMLQPPLGFRMNASSWPGYLCKILNNAMVAPEEIFQPEPPEPEENLFKVGQKLEAVDKKNPQLICCATVDAIKDDQIHVTFDGWRGAFDYWCNYRSRDIFPAGWCARSCHPMQPPGHKSR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDSSSSKQRCPRP--------------------------------------------------------------------------------------------------------------------------------------------------------------------RYTVVAESEAMVPASPATAHFHPNCKGGPFINNSKLPCMVTGPTYQTLAKLCLQEVLAASTDTQQLSKLLFALEGDVHIVTAAGKNFTVKIPSPMRMKDDESLAQFIETLCTTCRACANLISLVHETEECKKCANSRKRQLTQSATPPSSPVLADKRNRQSNSATTSPSEKIIKQELAVKSPVESKSKTSTNNGKEPASQQNSNHSLNNNNNSASKSSNKVVIKSEPNGANAQTSSTTQALRKVRFQHHANTNTNSSATNGNQDTSQTTHVSTSHCSSSSTSSSTSLAGGSANTSTIGKYLAPLVAEVHPEQANVKPSNSYYKSPTTLSSSASLPTSVSTPFTGCQSASS---------------------------TALAAGGVTAAKAATAPAGAAATAGASPSYTAITSPVSTPTSALANSHLRSQPIDWTIEEVIQYIESND-NSLAVHGDLFRKHEIDGKALLLLNSEMMMKYMGLKLGPALKICNLVNKVNGRRNNLAL--------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * *: **.** * .*. *:*: ** *:*::.**:** **** * *:*:*:*: * ********.*. ********:.:*:.:* **: *.:******: :*:**** :* : *..: :*. *: *** * * * * *:**:*:*** :** **:. : . :: : **** ******* : ******.*** : . :**** .. . . : . .: : * .. : : . . . ..* .: . .. . . : . .. : .: : * . : . : ..: . ..* : .** :. : : ..: . . : . . . . . . .* *::::*:*::. * : .:***:* :*:. :. . .: ", "identical_positions": 123, "similar_positions": 136, "identity": "9.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-549", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97607-1", "uniprot_id": "JAG2_RAT", "id": "P97607-1", "name": "Protein jagged-2", "aln": "------------------------------------------------------------------------------------------------------GACCDGDGRTTRAGGCGRDECDTYVRVCLKEYQAKVTPTGP---CSYGYGATPVLGSNSFYLPPAGAAGDRARARSRTGGHQDPGLVVIPFQFAWPRSFTLIVEAWDWDNDTTPD--EELLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGKFCDECVPYPGCVHGSC-VEPWHCDCETNWGGLLCDKDLNYCGSHHPCVNGGTCINAEPDQYLCACPDGYLGKNCERAEHACASNPCANGGSC--------------------------------------------------------------HEVLSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEG--------------------------------------------KPCLNAFSCKNLIGGYYCDCLPGWKGANCHININDCHGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELEYYKCASSPCRRGGICEDLVDGFRCHCPRGLSGPLCEVDVDLWCEPNPCLNGARCYNLEDDYYCACPEDFGGKNCSVPRETCPGGACRVIDGCGFEAGSRAHGAAP----SGVCGPHGHCVSLPGGNFSCICDSGFTGTYCHENIDDCMGQPCRNGGTCIDEVDSFACFCPSGWEGELCDINPNDCLPDPCHSRGRCYDLVNDFYCVCDDGWKDKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCTIAKNSSCVPNPCVNGGTCVGSGDSFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRSGPRCQEVVIFTRPCWSRG------------------VSFPHGSSWVEDCNSCRCLDGHRDCSKVWCGWKPCLLSPQP---SALSAQCPPGQQCREKAMGQCLQPPCENWGECTAEDPLPPSTP--------CLPRTTHLDNNCARLTLHFNRDQVPQGTTVGAICSGIRALPATRAAARDR--------LLLLLCDRASSGASAVEVAVSFSPARDLPDSSLI-----------QSTAHAIVAAITQRGNSSLLLAVTEVKVETVVMG-GSSTGLLVPVLCSVFSVLWLACMVICVWWTRKR--RKERERSRLPRDESANNQWAPLNPIRNPIERPGSSGLGTGGHKDVLYQCKNFTPPPRRAGEALPGPASHGAGGEDE------EDEELSRGDGRLSRSREVPLTQIHQRPQLLPGKA----SLLAPGPKVDNRAVRSTKDVRCAGRE-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYE5-1", "uniprot_id": "JAG2_MOUSE", "id": "Q9QYE5-1", "name": "Protein jagged-2", "aln": "--------------------------------------------------------MRARGWGRLPRRLLLLLVLCVQATRPMGYFELQLSALRNVNGELLSGACCDGDGRTTRAGGCGRDECDTYVRVCLKEYQAKVTPTGP---CSYGYGATPVLGGNSFYLPPAGAAGDRARARSRTGGHQDPGLVVIPFQFAWPRSFTLIVEAWDWDNDTTPD--EELLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGKFCDECVPYPGCVHGSC-VEPWHCDCETNWGGLLCDKDLNYCGSHHPCVNGGTCINAEPDQYLCACPDGYLGKNCERAEHACASNPCANGGSC--------------------------------------------------------------HEVPSGFECHCPSGWNGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEG--------------------------------------------KPCLNAFSCKNLIGGYYCDCLPGWKGINCQININDCHGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELEYDKCASSPCRRGGICEDLVDGFRCHCPRGLSGLHCEVDMDL-CEPSPCLNGARCYNLEGDYYCACPEDFGGKNCSVPRDTCPGGACRVIDGCGFEAGSRARGVAP----SGICGPHGHCVSLPGGNFSCICDSGFTGTYCHENIDDCMGQPCRNGGTCIDEVDSFRCFCPSGWEGELCDINPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCTIAKNSSCVPNPCVNGGTCVGSGDSFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRSGPRCQEVVIFTRPCWSRG------------------MSFPHGSSWMEDCNSCRCLDGHRDCSKVWCGWKPCLLSGQP---SDPSAQCPPGQQCQEKAVGQCLQPPCENWGECTAEEPLPPSTP--------CQPRSSHLDNNCARLTLRFNRDQVPQGTTVGAICSGIRALPATRAAAHDR--------LLLLLCDRASSGASAVEVAVSFSPARDLPDSSLI-----------QSTAHAIVAAITQRGNSSLLLAVTEVKVETVVMG-GSSTGLLVPVLCSVFSVLWLACVVICVWWTRKR--RKERERSRLPRDESANNQWAPLNPIRNPIERPGGSGLGTGGHKDILYQCKNFTPPPRRAGEALPGPAGHGAGGEDE------EDEELSRGDGDSPEAEKFISHKFTKDPSCSLGRP----ARWAPGPKVDNRAVRSTKDVRRAGRE-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y219-1", "uniprot_id": "JAG2_HUMAN", "id": "Q9Y219-1", "name": "Protein jagged-2", "aln": "--------------------------------------------------------MRAQGRGRLPRRLLLLLALWVQAARPMGYFELQLSALRNVNGELLSGACCDGDGRTTRAGGCGHDECDTYVRVCLKEYQAKVTPTGP---CSYGHGATPVLGGNSFYLPPAGAAGDRARARARAGGDQDPGLVVIPFQFAWPRSFTLIVEAWDWDNDTTPN--EELLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPGCVHGSC-VEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSC--------------------------------------------------------------HEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEG--------------------------------------------KPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDL-CEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAA----SGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRG------------------TPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQP---EALSAQCPLGQRCLEKAPGQCLRPPCEAWGECGAEE--PPSTP--------CLPRSGHLDNNCARLTLHFNRDHVPQGTTVGAICSGIRSLPATRAVARDR--------LLVLLCDRASSGASAVEVAVSFSPARDLPDSSLI-----------QGAAHAIVAAITQRGNSSLLLAVTEVKVETVVTG-GSSTGLLVPVLCGAFSVLWLACVVLCVWWTRKR--RKERERSRLPREESANNQWAPLNPIRNPIERPG-------GHKDVLYQCKNFTPPPRRADEALPGPAGHAAVREDE------EDEDLGRGEEDSLEAEKFLSHKFTKDPGRSPGRP----AHWASGPKVDNRAVRSINEARYAGKE-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TDN4-1", "uniprot_id": "A0A8N7TDN4_DANRE", "id": "A0A8N7TDN4-1", "name": "Delta-like protein", "aln": "---------------------------------------------------------MHNYFGACFSIVFLILTFWTEVCQSSGYLELQLISVENDRAELANGNCCDG----ARDGLCDQDQCDTYLKVCLKEYQVEVTTSGF---CTYGTGSSSVVGGNTFQLK--GFNGNPNKAN-------DLGTVIIPFQFAWPRAYTLIVEAWDWDNQTITESSDDQLIMRSVNRGEMNPGEERQVIQHKGRTASIQYSVRVRCDRHYYGNKCNKQCRPRDDYFGHYTCDQSGNQQCMEGWTGQDCKQAICKQGCSELHGSCETPGDCVCKYGWQGPLCDECLPYPGCKHGTC-VKPWTCTCEKNWGGLLCDKDLNYCGTHSPCVNGGTCLNTEPDEYFCLCPEGYSGENCHISKHACMSNPCANGGTC--------------------------------------------------------------HELASGFECLCPPGWDGPTCAKDKDECESNPCSYGGTCIDLENGFECLCLPQWTGKTCQIDVNECTR--------------------------------------------RPCLNAYACKNLIGGYHCNCYPGWAGPNCNININSCYGQCQNGGTCQDGRHGYVCQCQPGFMGRHCEVQQSRCASSPCQNGGRCRSLATGYECECLYGYTGNNCEVQVDL-CNPNPCQKKAQCHSLQGDFYCACADEYEGKTCSQLRDHCKTSTCHVIDSCTTAITTNGTEKAVRYILSNVCGPHGRCISQSGGNFTCACQPGFSGTYCHENINDCESSPCHSGGTCIDDIDSFRCVCPDGFDGQLCELEVNECSSDPCLNGGHCIDLLNDFYCRCTDNWKGKTCNSRENQCDSSTCANGGTCHDRGESFRCLCPSGWGGSTCNTAMNSSCESGPCLNGGTCIGSGSVFKCICKDGWEGPTCAQNVDDCNPHPCYNGGQCVDGVNWFRCECAPGFAGPDCRINIDECQSSPCSYGATCVDEINGYRCLCPMGRAGPRCQDFIGVGKACDRSG------------------LQVHHGGRWEDGCNSCQCMNGNIKCTKVNCGHQSCLLQSDSE--VAQRPLCPLGQECVEHHFLSCLRPPCDQLGMCSTRGRLQPINTR-------CLPNNGYLDVNCARVTLVFDSDTVPQGTTAEGVCTELTYLPITRTLAKDH--------ALFLLCDQSPSGHNAVEVAMSYEQNNFVDGPAQI-----------HDVVRSIIDVLSKPHNSTLLLAVREVRVDTQDP--HPQVGYLIPLLCVLFVVLWISCIIVCVWWFRRR--RKARQREDTQMEESINNQRGTLLSARTPH----------KDNTDPMQENKNLLYPLDRVGDGAEREEEEEEGDEES------NRGLALHKCSSLAYSKGDTVYVIHTSAQNQQHRT----HYGGKDNRCKNNVNERLSEHTKDHYV-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18168-1", "uniprot_id": "SERR_DROME", "id": "P18168-1", "name": "Protein serrate", "aln": "MYKMFRKHFRRKPATSSSLESTIESADSLGMSKKTATKRQRPRHRVPKIATLPSTIRDCRSLKSACNLIALILILLVHKISAAGNFELEILEISNTNSHLLNGYCCGMPAELRATKTIGCSPCTTAFRLCLKEYQTTEQGASISTGCSFGNATTKILGGSSFVLS------DP-----------GVGAIVLPFTFRWTKSFTLILQALDMYNTSYPD--AERLIEETSYSGVILPSPEWKTLDHIGRNARITYRVRVQCAVTYYNTTCTTFCRPRDDQFGHYACGSEGQKLCLNGWQGVNCEEAICKAGCDPVHGKCDRPGECECRPGWRGPLCNECMVYPGCKHGSCNGSAWKCVCDTNWGGILCDQDLNFCGTHEPCKHGGTCENTAPDKYRCTCAEGLSGEQCEIVEHPCATRPCRNGGTCTLKTSNRTQAQVYRTSHGRSNMGRPVRRSSSMRSLDHLRPEGQALNGSSSPGLVSLGSLQLQQQLAPDFTCDCAAGWTGPTCEINIDECAGGPCEHGGTCIDLIGGFRCECPPEWHGDVCQVDVNECEAPHSAGIAANALLTTTATAIIGSNLSSTALLAALTSAVASTSLAIGPCINAKECRNQPGSFACICKEGWGGVTCAENLDDCVGQCRNGATCIDLVNDYRCACASGFKGRDCETDIDECATSPCRNGGECVDMVGKFNCICPLGYSGSLCEEAKEN-CTPSPCLEG-HCLNTPEGYYCHCPPDRAGKHCEQLRPLCSQPPCNEGCFANVSLATSATTTTT----TTTTATTTRKMAKPSG------------------------LPCSGHGSCEMSDVGTFCKCHVGHTGTFCEHNLNECSPNPCRNGGICLDGDGDFTCECMSGWTGKRCSERATGCYAGQCQNGGTCMPG-------------------APDKALQP----------------HCRCAPGWTGLFCAEAIDQCRGQPCHNGGTCESGAGWFRCVCAQGFSGPDCRINVNECSPQPCQGGATCIDGIGGYSCICPPGRHGLRCEILLSDPKSACQNASNTISPYTALNRSQNWLDIALTGRTEDDENCNACVCENGTSRCTNLWCGLPNCYKVDPLSKSSNLSGVCKQHEVCVPALSETCLSSPCNVRGDCRALEPSRRVAPPRLPAKSSCWPNQAVVNENCARLTILLALERVGKGASVEGLCSLVRVLLAAQLIKKPASTFGQDPGMLMVLCDLKTGTNDTVELTVSSSKLNDPQLPVAVGLLGELLSFRQLNGIQRRKELELQHAKLAALTSIVEVKLETARVADGSGHSLLIGVLCGVFIVLVGFSVFISLYWKQRLAYRTSSGMNLTPSLDALRHEEEKSNNLQNEENLRRYTN-PLKGSTSSLRAATGMELSLNPAPELAASAASSSALHRSQPLFPPCDFERELDSSTGLKQAHKRSSQILLHKTQNSDMRKNTVGSLDSPRKDFGKRSINCKSMPPSSGDEGSDVLATTVMV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * **. . . * * .::******. :. *::* .:: ::*..:* * : . * :::** * *.:::***::* * * : .: : ** . * : * . : :.. *: * : :**:* **. .*.. ****:* ****:*.. *:: *::** * :*::*:** **. :** * **:* * **:* :*:**: **** **:* ..* * *:.****:***:***:**:* ** :**** *: **:* * *.:* *.:*. :*.* :.** ***:* ::: ..* * *..** **** : *** ..** ****:* .**.* * :* * .**:*.*** **:** *:* *.: * * ** * .* *::.* ***::*.** * :.* * * ** **.** : .**:***: ** * .:. :.* * * :* ** : * *.** : :* . .:** *. : ** *. * * .*. . . : : .. : :: ..* ** . *:* . . * * * * :*: : *:* .:** . * * * .** * * ..*..* * .* * : * ***** * :.: . * * ** * *:. ::*. **:*** * .*..**** ** **:*******::**...** ****:* *.** * ** ** * **: .: :.. . . :.**:* * :* *::: ** * * : * ** .**: * * : . * *. :: ****:*: : : * :*::. .:*: : * :: : *.:*** .. .:**:::* . . . : . : : : : * :: **:::* . . *: :** * ** .:.:.::* :: *. . :: .:: :. . .. : ..: . . : ... : :. : . : . :. . . ", "identical_positions": 338, "similar_positions": 300, "identity": "22.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-555", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88954-1", "uniprot_id": "MPP3_RAT", "id": "O88954-1", "name": "MAGUK p55 subfamily member 3", "aln": "----MPVLSEDSGLHETLALLTSQLRPDSNHR--EEMGFLRDVFSEKSLGYLMKIHEKLRYYERQS-PTPVLHSAMALAEDVMEEL-QAASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDNIDEDFEEESVKIVRLVKNKEPLG----------ATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGITVLHKRPDEISQILAQSQGSITLKIIPATQEEDRFKESKVFMRALFHYDPREDRAIPCQEAGLPFQQRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKQFQERRLSYRRTTGTIPSPQNLRKPLYDQPCDKETCDCDGYFKGHYVAGLRRSFRLGCRERLTGSQEVKVPVGAESQVLLTYEEVARYQHQPGERSRLVVLIGSLGAHLHELKQRVVAEDPQHFGVAVPHTTRPRKSHEREGVEYHFVSKQAFEADIQHNKFLEHGEHKENLYGTSLEAIQTVMAKNKVCLVDVEPEALRHLRTPEFKPYVIFVKP---AIQE--KRKTPPVSPDSEDPAT-PLDEQQQEMAASAAFIDQHYGHLIDTVLVRQDLQSVCSQLRAVIESLSKDTYWVPISWVR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88910-1", "uniprot_id": "MPP3_MOUSE", "id": "O88910-1", "name": "MAGUK p55 subfamily member 3", "aln": "----MPVLSEDSGLHETLALLTSQLRPDSNHR--EEMGFLRDVFSEKSLSYLMKIHEKLRYYERQS-PTPVLHSAMALAEDVMEEL-QAASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDNIDEDFEEESVKIVRLVKNKEPLG----------ATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRFKDSKVFMRALFHYDPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKQFQERRLSYRRTTGTLPSPQNFKKPPYDQPCDKETCDCDGYFKGHYVAGLRRSFRLGCRERLGGSQEAKVPTGAESQVLLTYEEVARYQHQPGERPRLVVLIGSLGAHLHELKQRVVAEDPQQFAVAVPHTTRPRKSHERDGVEYHFVSKQAFEADVHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALRHLRTPEFKPYVIFVKP---AIQE--RRKTPPVSPDSEDIAS-SLDEQQQEMAASAAFIDQHYGHLIDTVLVRQDLQEPAASS-----ELS-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13368-1", "uniprot_id": "MPP3_HUMAN", "id": "Q13368-1", "name": "MAGUK p55 subfamily member 3", "aln": "----MPVLSEDSGLHETLALLTSQLRPDSNHK--EEMGFLRDVFSEKSLSYLMKIHEKLRYYERQS-PTPVLHSAVALAEDVMEEL-QAASVHSDERELLQLLSTPHLRAVLMVHDTVAQKNFDPVLPPLPDNIDEDFDEESVKIVRLVKNKEPLG----------ATIRRDEHSGAVVVARIMRGGAADRSGLVHVGDELREVNGIAVLHKRPDEISQILAQSQGSITLKIIPATQEEDRLKESKVFMRALFHYNPREDRAIPCQEAGLPFQRRQVLEVVSQDDPTWWQAKRVGDTNLRAGLIPSKGFQERRLSYRRAAGTLPSPQSLRKPPYDQPCDKETCDCEGYLKGHYVAGLRRSFRLGCRERLGGSQEGKMSSGAESPELLTYEEVARYQHQPGERPRLVVLIGSLGARLHELKQKVVAENPQHFGVAVPHTTRPRKSHEKEGVEYHFVSKQAFEADLHHNKFLEHGEYKENLYGTSLEAIQAVMAKNKVCLVDVEPEALKQLRTSEFKPYIIFVKP---AIQE--KRKTPPMSPACEDTAA-PFDEQQQEMAASAAFIDRHYGHLVDAVLVKEDLQGAYSQLKVVLEKLSKDTHWVPVSWVR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WFJ8-1", "uniprot_id": "X1WFJ8_DANRE", "id": "X1WFJ8-1", "name": "", "aln": "MKEAMPVLSAGGGLHETLALLTSQLRPDANHK--EDMVFLRDVFSERSLSCLMKIHEKLRQYEKQS-PTPVLHSASTLAEDVAEEL-QSGPMSVEEKELLHLLTSPHLKAVLSVHDTVAQKNFDPVLPPLPDDFEDELDEESVKIVRLVKNKEPLG----------ATIRRDESTGAVIVARIMKGGAADRSGLVHVGDELREVNGSSVMHKRPDEISQLLSQSQGSITLKIIPAIKEEDKLQENKVYMRALFDYTPLEDKATPCQEAGLPFKRGDVLQVVSQDDQTWWQAKRIGDCNLRAGLVPSKQFQERRLAYRIKMGTLQNSKSPKKAVYDQGCDKEDCDCEGYFNGQYIAGLRRSFRLSRKDRRGSSGEANVSDQNDTD-FLTYEEVTRYQQRSNERPRLVVLIGSLGARINELKQKVIAENPHRYAVAVPHTTRPKKSHEKEGVEYHFVTKQAFDADAQNNKFIEYGEYKENLYGTSIEAIRSVQAKNKMCLVDVQPEALKALRTAEFKPYVIFVKP---KIPESRRRRSAATSPGGGEHGR-ITEEDLQEMRLSAQQIDQQYGHLVDRVLIKEDTASASTELRSILERLERETFWVPISWVRP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z8G0-1", "uniprot_id": "A1Z8G0_DROME", "id": "A1Z8G0-1", "name": "", "aln": "--MLEAVMASDINWDPALSKLISTLKESENLSNDQEIDFLKALLESKELNALVNVHTKVAKVGRDDRLAPVLSTSAQVLYEVLEQLSQHCHLNDDCKEAFHLLQDSHLQHLLFAHDAIAQKDFYPHLPEAPVEMDE--DEETIKIVQLVKSNEPLTGAQSTEPIVGATIKTDEESGKIIIARIMHGGAADRSGLIHVGDEVIEVNNINVEGKTPGDVLTILQNSEGTITFKLVPADNK-GAQRESKVRVRAHFDYNPDVDPYIPCKEAGLAFQRGDVLHIVAQDDAYWWQARKEHERSARAGLIPSRALQERRILHDRTQKNGTDLDS--KP---GSCASLCTTPPGSPR-LPASSSTSSCRQPKTKKIMY--DLTENDDFDREQIATYEEVAKLYPRPG-VFRPIVLIGAPGVGRNELRRRLIARDPEKFRSPVPYTTRPMRTGEVAGREYIFVAREKMDADIEAGKFVEHGEYKGHLYGTSAESVKSIVNAGCVCVLSPHYQAIKTLRTAQLKPFLIHVKPPELDILKATRTEARAKSTFDEANARSFTDEEFEDMIKSAERIDFLYGHFFDVELVNGELVNAFEQLVQNVQRLENEPVWAPSMWVQ-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*:: . . . :*: * * *: . * ::: **: ::..:.*. *:::* *: ::. :*** :: : :* *:* * : : :* ::** .**: :* .**::***:* * ** * :::: :**::***:***.:*** ***: ** :* :::****:*********:*****: ***. * * *.:: :* :*:*:**:*::** :: . ::.** :** *.* * * **:****.*:: :**.:*:*** ****:: : . ****:**: :****: : . . .. *. * . * . :. * * .: : . : : *****:: :.. * :****: *. :**:::::*.:*.:: .**:**** :: * * ** **::: ::** . .**:*:**:* :***** *::::: . :*::. . :*:: ***.::**::*.*** * : : .: . *. . :*: ::* ** ** ***:.* *:. : . *. ", "identical_positions": 190, "similar_positions": 187, "identity": "31.15%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-559", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZA12-1", "uniprot_id": "CHD6_RAT", "id": "D3ZA12-1", "name": "ATP-dependent chromatin remodeler CHD6", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKMKIQKKEKQLSKLRALNHSPMSDASVNFDYKSPSPFDCS---PDQGENIEEAANHCLPQKDFYTTEEEADTLFSRKLMSHNGMEDNGG-----------------------------------------------------------------------------------------------------------------------------------------------------------------RGTGVKKKRKKKEPGEQEG-TKASK-----------------------------------------------------------------------DREPKPKRKREPKEPKEPRRAKEPKRAKEPK--EAKQKDGVKKPRKPREASGTKE----------------------------------------------------------------------------------------------GKEKRSCTDCGPRTKPKKASKDQGPTPVERKKKGKRKNETTVESLELDQSLPNPSLQSP-EEPSESADSQKRRSGRQVKRRKYNEDLDFKVVDDD---------------------------------------------GETIAVLGAGRTSALSASTLAWQAEEPP------------------------EDDANIIEKILASKTV-QEVHPGEPPF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DLELFYVKYRNFSYLHCKWATMEELEK-DPRIAQKIKRFRNKQAQMKHIFTEPDEDLFNPDYIEIDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPAKVKEFESLQILP---EVKPVERPASDAWQKLETSREYKNSNRLREYQLEGMNWLLFNWYNRKNCILADEMGLGKTIQSIAFLSEIFVRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHGSQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVVIDEAHRLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGDLKTEEQVKKLQSILKPMMLRRLKDDVEKNLAPKQETIIEVELTNIQKKYYRAILEKNFSFLTKGANQHNMPNLINTMMELRKCCNHPYLINGAEEKILEDFRKAHSSEASDFQLQAMIQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDILEDYLIQRRYTYERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAILQDINRKGSTNG-VQQLSKMEVEDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGSTFAKASFVASGNRTDISLDDPNFWQKWAKIAELDTEAN--NEKESLVIDRPRVRKQTKHYNSFEEDELMEFSELDSDSDE------RPTRSRRLSDKARR---------------------------YLRAECFRVEKNLLTFGWGRWKDILTHGRFKWPLNEKDMEVICRALLVYCVKHYKGDEKIKSFIWELITPSKDGQVQTLQN-HSGLSAPVPRGRKGKKTKNQLLLPELKTADWLATCN-----------------------------------------------PEVVLHDDGYKKHLKQHCNKVLLRVRMLYYLKAEILGEAADKAFEGTPARELDVLLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRADPALCFLEKVGMPDE--------------------------------------------------------------------------------------------------KSLSAEQGVTDGTSDIPE-------------------------------------------------------------------------------------------------------------RGNIDKEDSAEDKVDGLQKQTASPSDGSDGIFG---EKKDDSQ-------------AVSSALTARLRRLVTIYQRCNRKE-----------------------------------------------------------------------------------------------------------------------LCRPEILGPGNQG--YWVQEEVFRRTSDMDLINKEAQKR--------WTRREQADFYRTVSSFGVVYDQEK---------EAFDWTQFRAISRLDKKSDENLEHYFHSFVAMCRNVCRLPTWKDDGPPDASIYVEPITEERAAKTLYRIELLRKVREQVLTCPQLHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGLNRTDYYIMNDPQLSFLDAYRNYAQHKRTDTQAPGS---LCCLYQGNSKLYES------------LTYTPMSRTS----------ESLESEPENLVKMDSRDD---HLCLPEAGLPDITCENFVSKVQEVIS-LDHDESLLPESLENMMYGKTGLS----QEPRSFQEAPSTNMQSRKKTVTVSASRDESCQLPGIEAEITSASSLMSSLEAG-VAKMNIKNGKHLLVSISEEGEPCCSETGRSPESR--GRLEARCLASPTLDTGHE------SGFVDLCSLSVYDS-----------------------KRNFSSDQQLIDLLENKSLENKLILNQ----SDEEEEENEKETLAIVASTTEKPAVLDFTQPTASIPRGKNLSFHQDEAK--------------KGRLEVGSKTP------GPQRAFP-PSANQCHCKHIERWAHG------LGSEESEGEKPKAYEPDPYRSKANNTTVEGEPAIIPTEP----------------------------------FKLKHELLKEPWKESSEGGKSFSMYVPEG---SEPKSEEMDFENKDDYEKDGACHSQDYPGKYSEEESKSSASGIAGDLG------------EEAQEVRAPTIAQLLQEKTLYSFSEWPKDRVIINRLDNICHVVLKGKWPCS-HQYEPSGALPTPVLSSSAGSRSSLSE---PEATEHSFSNGAALAAQIQKESFLAPVFTKDEQKHRRPYEFEVERDAKARSL---EEYSASHGRPPIVLNGWHGESAIDLSCSSEGSPGATS------PFPVSASTPKIGAISSLQGALGMDLSGILQAGLIHPVTGQIVNGSLRRDDAAMRRRRGRRKHIEGGMDLIFLKEQTLQAG----------ILEVHEDAGQTTLNTTHPEGPGAASSASEPTAAAS-----SQAEKAVPSKSLLDWLR----------QQADYSLDVPGFGAS--------FSDKPKQRRPRCKEPGKLDIGSLGGEERVSAVPKEPGLR-------------------------------------------------------------------------GFLPESKFNHTLAEPVLRDAGPRRRGRRPRNELLKAPAIVADSPSGMGPLFMNG----------------------------------------------------------LIAGMDLVGLQNVRNIPGIPLTGLVGFPAGFATMPTGEDVKNTLS-----------------------------------------------------MLPMMLPGMATVPQMFG-------------VGGLLNTPMATTCTTTASASLAS-TKSGASATEKTTE-------DELSGRDVKADSLVEDK--------------------PGPSPFSDQSEPTITTSSPVAFNPFLIPGVSPGLIYPSMFLS---------PGMGMALPAMQQGRHS----------------EMAGLETQKRKKKKTKGDNP--TPEPAS--VCEREPGSDQNCTESSVTVSPEREHVAQAREEGLKDSNDDTN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A3KFM7-1", "uniprot_id": "CHD6_MOUSE", "id": "A3KFM7-1", "name": "ATP-dependent chromatin remodeler CHD6", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKMKIQKKEKQLSKLRALNHSPMSDASVNFDYKSPSPFDCS---PDQGENIEEAANHCLPHKNLYTTEEEADTLFSRKLTSHNGMEDSGG-----------------------------------------------------------------------------------------------------------------------------------------------------------------RGTGVKKKRKKKEPGEQEG-TKGSK-----------------------------------------------------------------------DREPKPKRKREPKEPKEPRRAKEPKRAKEPK--ETKQKDGVKKPRKHREASGTKE----------------------------------------------------------------------------------------------GKEKRSCTDYGSRTKSKKASREQGPTPVERKKKGKRKNETTVESLELDHSLPNPSLQSP-EEPSESADSQKRRSGRQVKRRKYNEDLDFKVVDDD---------------------------------------------GETIAVLGAGRTSALSASTLAWQAEEPP------------------------EDDANIIEKILASKTV-QEVHPGEPPF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DLELFYVKYRNFSYLHCKWATMEELEK-DPRIAQKIKRFRNKQAQMKHIFTEPDEDLFNPDYIEIDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPAKVKEFESLQILP---EVKHVERPASDAWQKLETSREYRNSNRLREYQLEGMNWLLFNWYNRKNCILADEMGLGKTIQSIAFLSEIFVRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHGSQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAHRLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGDLKTEEQVKKLQSILKPMMLRRLKDDVEKNLAPKQETIIEVELTNIQKKYYRAILEKNFSFLTKGANQHNMPNLINTMMELRKCCNHPYLINGAEEKILEDFRKAHSSEASDFQLQAMIQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDILEDYLIQRRYTYERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAILQDINRKGSTNG-VQQLSKMEVEDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGSTFAKASFVASGNRTDISLDDPNFWQKWAKIAELDTEAN--NEKESLVIDRPRVRKQTKHYNSFEEDELMEFSELDSDSDE------RPTRSRRLSDRARR---------------------------YLRAECFRVEKNLLIFGWGRWKDILTHGRFKWPLNEKDMEMICRALLVYCVKHYKGDEKIKSFIWELITPSKDGQVQTLQN-HSGLSAPVPRGRKGKKTKNQLLLPELKNADWLATCN-----------------------------------------------PEVVLHDDGYKKHLKQHCNKVLLRVRMLYYLKAEILGEAADKAFEGTPARELDVLLPDIDYVEIPVDWWDAEADKSLLIGVFKHGYERYNAMRADPALCFLEKVGMPDE--------------------------------------------------------------------------------------------------KSLSAEQGVTDGTSDIPE-------------------------------------------------------------------------------------------------------------RGNIDKEDSAEDKLDGLQKQTASPSDGSDGIFG---EKKDDSQAAQDGSDPDKSPWPVSSALTARLRRLVTIYQRCNRKE-----------------------------------------------------------------------------------------------------------------------LCRPEILGPGNQG--YWVQEEVFRRTSEMDLINKEAQKR--------WTRREQADFYRTVSSFGVVYDQEK---------KAFDWTQFRIISRLDKKSDESLEHYFYSFVAMCRNVCRLPAWKDDGPPDASIYVEPITEERAAKTLYRIELLRKVREQVLMCPQLHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGLNRTDYYIMNDPQLSFLDAYRNYAQHKRTDTQAPGS---LCCLYQSNSKLYES------------LTYTPVSRTS----------ESLESEPENLMRMESRDD---HLCLPEGGLPDITCENFVSKVQEVIS-LDHDENLLPESLENMIYGKTGLS----QEPHSFQEAPTTNTQSRKNTITISASRNESCQPPGIEAEITSASSLMSSLEAG-VAKMNIKNGKHLLVSISKEGEPCCSETGRRPETI--GHREAKCLVSPTLDTGHE------SGFVDLCSLSVYDP-----------------------KRNFSSDQQLIDLLENKSLESKLILNQ----SDEEEEENEDETLAIVASATEKPEVLDFPKPTVNIPRGKNLSFHQDEAK--------------KGRLEVVSKTA------GPQRVFP-PPANQCHCKHIERWAHG------LGSEDSEVEKPKAYQPDLYRSKANNSTVEGETAVIPTEP----------------------------------FKLKHELLKEPWKESSEGGKSFSMYAPEG---SEPKPEDMDFENKDDYEKDGTCLSQDYPGKYSEEESKSSASGIAGDLG------------EEAQEVRAPTIAQLLQEKTLYSFSEWPKDRVIINRLDNICHVVLKGKWPCS-HQYEPSGALPTPVLSSSAGSRSSLSE---PEATEHGFSNGAALAAQIQKESFLAPVFTKDEQKHRRPYEFEVERDAKARSL---EEYSATHGRPPIVLNGWHGESAIDLSCSSEGSPGATS------PFPVSASTPKIGAISSLQGALGMDLSGILQAGLIHPVTGQIVNGSLRRDDAAMRRRRGRRKHIEGGMDLIFLKEQTLQAG----------ILEVHEDAGQTTLSTTHPEVPGATSSAPEPTAAAS-----SQAEKAVPSKSLLDWLR----------QQADYSLDVPGFGTS--------FSDKPKQRRPRCKEPGKLDISSLGGEERVPAVPKEPGLR-------------------------------------------------------------------------GFLPESKFNHTLAEPVLRDAGPRRRGRRPRNELLKAPAIVADSPSGMGPLFMNG----------------------------------------------------------LIAGMDLVGLQNVRNIPGIPLTGLVGFPAGFATMPTGEEVKNTLS-----------------------------------------------------MLPMMLPGMAAVPQMFG-------------VGGLLNTPMATTCTTTASASLAS-TKSGTSATEKSTE-------DKLSGHDVNTDALVDDK--------------------PGPSPFSDQSEPTITTSSPVAFNPFLIPGVSPGLIYPSMFLS---------PGMGMALPAMQQARHS----------------EMVGLETQKRKKKKTKGDSP--TQEPAS--VCEKEPGSDQNCTESSATVSPEREHVAQAREEGLKDSNEDTN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TD26-1", "uniprot_id": "CHD6_HUMAN", "id": "Q8TD26-1", "name": "ATP-dependent chromatin remodeler CHD6", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKMKIQKKEKQLSNLKVLNHSPMSDASVNFDYKSPSPFDCS---TDQEEKIEDVASHCLPQKDLYTAEEEAATLFPRKMTSHNGMEDSGG-----------------------------------------------------------------------------------------------------------------------------------------------------------------GGTGVKKKRKKKEPGDQEGAAKGSK-----------------------------------------------------------------------DREPKPKRKREPKEPKEPRKAKEPKKAKEHK--EPKQKDGAKKARKPREASGTKE----------------------------------------------------------------------------------------------AKEKRSCTDSAARTKSRKASKEQGPTPVEKKKKGKRKSETTVESLELDQGLTNPSLRSP-EESTESTDSQKRRSGRQVKRRKYNEDLDFKVVDDD---------------------------------------------GETIAVLGAGRTSALSASTLAWQAEEPP------------------------EDDANIIEKILASKTV-QEVHPGEPPF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DLELFYVKYRNFSYLHCKWATMEELEK-DPRIAQKIKRFRNKQAQMKHIFTEPDEDLFNPDYVEVDRILEVAHTKDAETGEEVTHYLVKWCSLPYEESTWELEEDVDPAKVKEFESLQVLP---EIKHVERPASDSWQKLEKSREYKNSNQLREYQLEGMNWLLFNWYNRKNCILADEMGLGKTIQSITFLSEIFLRGIHGPFLIIAPLSTITNWEREFRTWTEMNAIVYHGSQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSCVIIDEAHRLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGDLKTEEQVKKLQSILKPMMLRRLKDDVEKNLAPKQETIIEVELTNIQKKYYRAILEKNFSFLTKGANQHNMPNLINTMMELRKCCNHPYLINGAEEKILEDFRKTHSPDAPDFQLQAMIQAAGKLVLIDKLLPKLIAGGHKVLIFSQMVRCLDILEDYLIQRRYTYERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGGTNG-VQQLSKMEVEDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTHTITIQSEGKGSTFAKASFVASGNRTDISLDDPNFWQKWAKIAELDTEAK--NEKESLVIDRPRVRKQTKHYNSFEEDELMEFSELDSDSDE------RPTRSRRLNDKARR---------------------------YLRAECFRVEKNLLIFGWGRWKDILTHGRFKWHLNEKDMEMICRALLVYCVKHYKGDEKIKSFIWELITPTKDGQAQTLQN-HSGLSAPVPRGRKGKKTKNQLLIPELKDADWLATCN-----------------------------------------------PEVVLHDDGYKKHLKQHCNKVLLRVRMLYYLKAEILGEAAEKAFEGSPARELDVPLPDIDYMEIPVDWWDAEADKSLLIGVFKHGYERYNAMRADPALCFLEKVGMPDE--------------------------------------------------------------------------------------------------KSLSAEQGVTDGTSDIPE-------------------------------------------------------------------------------------------------------------RGNTDKEDNAEDKVDGLQKQTESSSDGGDGVFS---EKKDDSRAAQDGSDPDKSPWPVSSALTARLRRLVTVYQRCNRKE-----------------------------------------------------------------------------------------------------------------------LCRPEILGPGNQG--YWVQEEMFRRTSEMDLINKEAQKR--------WTRREQADFYRTVSSFGVVYDQEK---------KTFDWTQFRIISRLDKKSDESLEQYFYSFVAMCRNVCRLPTWKDGGPPDTTIYVEPITEERAARTLYRIELLRKVREQVLKCPQLHERLQLCRPSLYLPVWWECGKHDRDLLIGTAKHGLNRTDCYIMNDPQLSFLDAYRNYAQHKRSGTQAPGN---LCCLYQTNSKLYES------------LTYSQMSRTS----------ESLENEPENLVRVESRDD---HLSLP-----DVTCENFISKVQDVIS-INHDESLLPESLESMMYGKKVLS----QEPSSFQESPSTNTESRKDVITISISKDGNCQSGGPEAEIASGPTFMGSLEAGGVAQANIKNGKHLLMSISKEGELCCSEAGQRPENI--GQLEAKCLASPSLNPGNE------SGFVDMCSLSVCDS-----------------------KRNLSSDQQLIDLLENKSLESKLILSQNHSDEEEEEEENEEENLAMAVGMGERPEVLHLTEPTTNISREKNQGF-QDETK--------------KGSLEVANQTP------GLQRAFPAPAACQCHCKHMERWMHG------LENDEFEIEKPKAYIPDLFKSKTNTIAMEGEPTAIPSQP----------------------------------FKVKHELLKEPWKESAEGQNVFPTYPLEG---SELKSEDMDFENKDDYDRDGNCHSQDYPGKYSEEESKSSTSGITGDIG------------DELQEARAPTIAQLLQEKTLYSFSEWPKDRVIINRLDNICHVVLKGKWPSS-QQYEPSGTLPTPVLTSSAGSRTSLSE---PEAAEHSFSNGAALAAQIHKESFLAPVFTKDEQKHRRPYEFEVERDAKARGL---EQFSATHGHTPIILNGWHGESAMDLSCSSEGSPGATS------PFPVSASTPKIGAISSLQGALGMDLSGILQAGLIHPVTGQIVNGSLRRDDAATRRRRGRRKHVEGGMDLIFLKEQTLQAG----------ILEVHEDPGQATLSTTHPEGPGPATSAPEPATAAS-----SQAEKSIPSKSLLDWLR----------QQADYSLEVPGFGAN--------FSDKPKQRRPRCKEPGKLDVSSLSGEERVPAIPKEPGLR-------------------------------------------------------------------------GFLPENKFNHTLAEPILRDTGPRRRGRRPRSELLKAPSIVADSPSGMGPLFMNG----------------------------------------------------------LIAGMDLVGLQNMRNMPGIPLTGLVGFPAGFATMPTGEEVKSTLS-----------------------------------------------------MLPMMLPGMAAVPQMFG-------------VGGLLSPPMATTCTSTAPASLSSTTKSGTAVTEKTAE-------DKPSSHDVKTDTLAEDK--------------------PGPGPFSDQSEPAITTSSPVAFNPFLIPGVSPGLIYPSMFLS---------PGMGMALPAMQQARHS----------------EIVGLESQKRKKKKTKGDNPNSHPEPAP--SCEREPSGDENCAEPSAPLPAEREHGAQAGEGALKDSNNDTN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T870-1", "uniprot_id": "A0A8N7T870_DANRE", "id": "A0A8N7T870-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNPARALGHRRRHKEQEKMKIQKKDKQMSASYVLKHTPSAAASNASDQNAQTTFPIGHLGKEQLRIIGGPPNHCMAHPKHSGPAVSSHSLRPSMINNE---EDDGG-----------------------------------------------------------------------------------------------------------------------------------------------------------------GGTKVKKKRRKKDKKESEWHEDGQS-----------------------------------------------------------------------NAKPKRREQKEGKE-ILPRKTKTAKEQKDHKKRDAKAQKEVKKVKKGQDVKVKTL----------------------------------------------------------------------------------------------AKN--QCATHTPSKRGRKP-KEQGAMPPEKKKKGKRKSDAVLEMVESDDTASLSTLATGGEESTDPMDNTKRRSGRQVKRRKYNEDLDFKVVDDD---------------------------------------------GETIAVLGSGRIAAMSSSTLAWQAEEPP------------------------EDEANIIEKILSVRTVNKEMAPDEPPE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EMEEFYVKYRNFSYLHCKWATLEELEK-DPRIHQKIKRFRNKQAQMKHIFTEPDEDLFNPDYIEVDRVLEIAITTDTETGEEVTHYLVKWCSLSYEESTWELQEDVDPVKIKEFEELKKVP---EMKHVERPLPEQWQKLEKSRDYRNGNQLREYQLEGMNWLLFNWYNRKNCILADEMGLGKTIQSITFLYEIFLMGLRGPFLIIAPLSTITNWEREFRTWTEMNVIVYHGSQISRQMILQYEMYHRDEQGNIMSGEFKFQGVITTFEMIMADCPELKKINWRCVVIDEAHRLKNRNCKLLEGLKLMNLEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETTFLEEFGDLKTEEQVKKLQAILKPMMLRRLKDDVEKNLAPKEETIIEVELTNIQKKYYRAILEKNFAFLAKGANQHNMPNLINTMMELRKCCNHPYLITGAEEKILESFRKTYSSDAADFQLQAMIQAAGKLVLIDKLLPKLLAGGHKVLVFSQMVRCLDILEDYLIQRRYTYERIDGRVRGNLRQAAIDRFSKVDSDRFVFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAVLQDINRKGSLNG-VQQLSKMEVEDLLRKGAYGALMDEEDEGSKFCEEDIDQILQRRTQTITIQSEGKGSTFAKASFVSSGNRTDISLDDPNFWQKWAKIAELEIDSK--AEKESLVIDTPRVRKQTRHYNSFEDDELMEFSELDSDSEE------RPCRTRRLSDRNRR---------------------------YLRAECFRVEKNLLIFGWGRWKDILNHGRFKWHLAERDMEVLCRALLVYCVRHYKGDDKIKSFIWDLITPTEDGHNQALQN-HSGLSAPVPRGRKGKKLKNQLSPPELKNADWLAHCN-----------------------------------------------PEVVLQDDSYKKHLKQHCNKVLLRVRMLYYLKVEVLGDAATQALEGIPSSKLEVTLPDIDYIEIPTIWWDAEADKSLLIGVHKHGYERYNAMRADPALCFLERVGMPDV--------------------------------------------------------------------------------------------------TALTVEQSGAETPSDAPDGI----------------------------------------------------------------------------------------------------SKSDEIKEENHVKSEELEEKVEIKEEPMSDETAKNDNMVTGCFVASLAGDLTAELMEQGRIQWPAGSALTARLRRLITAYQRYTRRE-----------------------------------------------------------------------------------------------------------------------PLRHDFLLHEGIAPVAWQIGEFRHCTTEPDPLFLEWQRR--------WTRREQADFYRTVSSFGVVYDPEK---------KNFDWSQFRALARLERKTDESLERYFHSFVSMCRTACRLPPRKDEGNVDPSLFVDPITEERAARTLYRIELLRKVREQVLRHPLLGARLQLCRPSLYLPVWWECGKHDRDLLIGVAKHGLSRTDFYILNDPQLSFLEAHRNYVHKENHRYPVPGLPHHHCCLYDANIGHCQSPQPPEYHPTPAHHTPTQLVHTHGHHQ------SSEASEPGSSLGIGSGNREGFLDCPPLDDSLELGSLQHEGLTSDTLHGKSGKEAFNGFPFNSATGGQNMLNSYGVQGELNGTQGDMADSIAGKLRSDVLVGEQGSSEETGLMAPSVELDELQTPWESSDHAETSDMFNEADPILGAQALEPSFLDAPQPDDGQEGDETLTDCLSMPSSDSQSNPVEPLAPSFMLFKDLNVGETSVDQTDLSASLPEYVPPPPLGLPDVSLDQADPLNEEQEDKLSDSNITPCVP---SPEEEAESMGFNFEKEDLSPDSQKTKDTQDDMPSIESPSENCLDESQKEDCKVPFDDSIERDLKDPCEMALEEPYEKPLREPEKVPLEESYDLTCDETLQEPCDG------FQQDAVEQQLMEKPSGETCKEPSDSIENCNLTNTTLSAD----------------------------------YPLPPSLPSSPTTLPDTSVSPVLDVVPKQEFLMDPMVSEVKPEPDSTTQTPHLEQTEALEIKDKIKDESAKTPVLLGDVDSPRFALPICEMADSVHEIREPTIAQLLQEKALFSFSEWPKDRVIINRIDSICHTILKGKWPSSSQQFESPTSLANTCVPSSAHQRAGFLPNRMPISQSLNFNLSHTVPHIQKQERLVTPTFIPELKRPRRGFEFEAEVLAKPSHLGDKIQVGVSHRANALLINGWQ-DAAIDLSKPAELTVGGDSGPIGHMSHTVQSAAHKITGIGSIQGSLGLDMAGILQAGLIHPVTGQIVNGSLRRDDSMLRRRRGRRRNVET-ADLSFIKGRSINLPEQQSGAESISHPVVSSTSSQSECPPATPTTLSSHSATPSPAAAAATETLSASVDRETANKGLMEWLR----------QNPNYNMELSAFPASQNAGMLHSFLDRPKQRRHRCKDPSKLDVNSLTGEERVPVVHRNTGRRLGGAMAPAIKELSRWLDANSEYSVAPDWADVVK--------------------------------------HSGFLPEGKFTRILSGPVSRDPGPRRRGRRPRTEMPKAP----ELPAGMGSLFMNGG---------------------------------------------------------LIGSMDLVSLPNLRNVPGIPLTGIMGFPHGFATAVSSDDAKNGLS-----------------------------------------------------MLPMMLHGMATVQPPMYS----------AHMSGMISQPMSTATSTMSTVTASSTTASVTLTNSATVTSTSVDSSDTAPPQDNASSPVSSEKGNKEDAKQGGEDKKTSASVSTAAATSSSNSSSITSTGSHLTFNPFLIPGMSHSLLYPHMFLP---------PGSIMALPAMPAADSTGSPKRKRKKVREEGLVEGSGILGTQIDGEESKGVKDEQTPELKSQEARVEENGPDVDLAPTNLIKAPSEDKRTEENEKTEQDAQGD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z002-1", "uniprot_id": "B7Z002_DROME", "id": "B7Z002-1", "name": "", "aln": "MDGNAQNMFHGNHQGDPYYRYDAAAAAAAAAAANPRAMGPPGGYPPRHRPPHPLQQQPQYPSYQPTAENLYGLGAADHQAAMGLGVGVGVGAGMGDLSGWGAAPSVPGQAAAYPGAGLGAYGHPQAAPPSQQQRQSNASAYRQHMPAYGQQDQQKLASYGAQQSMMAGYGSLAPQQQQQQQPPTPQQQQQAQQVQQQAQQQQQQQQQQSQQQARLPQHYPQAPGQHPLYPGVGAPTVQAGQPPTPQAYAHSPYGSPMQHQPSRGAPQHVGYGHTGLDQASAYGQHVPGGAPPGHHLSAQQQQAAQQLGAHQQQQLQSQQQQQAQQQQPHVSLMQQQQLPGAGLPPPHMGMPPSYGSHHQQQQQQQQTQQQQQQSAPPYMSSSKHQQAAAQLNSSPQYRAPFPQLSPQMSPRPPTMSPHPQMSPRPVGVSPAKPPPPQQQQQQTQAQQPQQVVSNQPSQHSIQGMVGLPSPRPQPPTSGAGGAGAKGPAPVAAPVNTLQALEQMVMPSQALGLPPMDYPSAYRSAVGPRMPASPQQQQQQHQQWGAAHGAQHLAALQQQQAQQQQQQVQQQQQAPPQQQQQAAMLQAQQQHHQQQLSMYGQPMGQQPQTAQQQVVPPVTSQPPVVAASQQQQQQQHQQQSLNDQLQHSINDIVGGGNSSGATGGAQNQHQQQPQLAAMSSPLHQQNLPNMHHLIQPTMETTQPTQQQQQTSQQQQQPQQPQATLTSPHHQQMQHQSPIHQQQQSPHHQQHLPSYNQSQQQFDPFANILGDNQPAASQQTMSPAHVSSPVPAQMQQQQHQTQQQPSQQVPQSQQQQVSQPQQQTQQQQPSTPSHHLSSILNETANSNDSSTLAVAANDSNNSSSNSSTNSIVNNQPTSVHDSNSQSSINSSSNNQQQLLMDNTNSHGGNSESAQNAGVDVGLFDNNSMSSNSAAVAAVASNAASAAAALLDSNSQSSNAEFEKNQSEGEGLGVVEGVIANETDLPQDENSVSKTQDITLSTELPTIQDDLQEKPTAEMEQTQLGQSLGDLSKSLLEEPKTVEESGEDKSQSAPGVAPPADPIIPVTQPPQQQMPPIGMPMHPIAPGYEAQAQGQGHMPPMMPPYGGAPGMYPPYPMLHQQEIAALQQQIQELYCMPPGHELQHQDKLMRMQERLNLLTQHEVNDQCAGGPQCLLFQNVPPMYGPPGNPLLNQQMVESPQVSSTTGRGRGKSANKPRKPRAKKGEKAQVGQQQDLMDISGNVAMGAANAVSSIPTTQLPVSEDCVTQGAGDTSVVGMLEYSEGMGDLSQDVHSANELDTSTDGSGKKKKPRKPRTPKDPNKPPRDRTPKAKKPKDPNDPNSTETPAAVKKRAGASKRRKQYGEDGAEQTGEGSEVEDNKPLVPKAGSADGEAETTSGGTGVDGESPDYDDIPVSKIPRGSNEDEKEAEAGDETVDSVPDSAGDPASTPSRRDRKRSTARSRRNANSEEGGSARKNRGSLSAKALKKRRNRGRIVPESDGEDDTLDRTPPPSP--PPDSEMDSNKRRSSRNTQRKKYIDDVMLRFSDDENSLLVASPVKKDKKPSANASNSNAGSDVEKTEPQSGAEGDAAQEVGEEKSNLPLDESSQLEASSSTSAVAEKERQISTDAANAAMSSKPNYVYINTGDEDSMVVQLVLAMRMGKRELILDKPKEKAPEPKQDEEKSELDEATTDKPEGDEKFKTEGESKKDLTDSEETKLESSAMEVDSKEESEPDDSKKSDEDNKDKDKMEVDDEVGKSDKESKPEEQSETVKTEENSKAIEEDKSSTVLTADHAKEPETVLEKMEVDEKANDDQSAVSKAEGSDEKSTDDSNPEEATTEKNKESLEIEGEKERVKEGEESVKKENDEKTEADMENKPEPVFIDVEEYFVKYRNFSYLHCEWRTEEELLKGDRRVAAKIRRFQQKQSQQLNIFENIEDEPFNQDFTEVDRVLDMSVHTDETSGETTKHYLVKWKSLPYEDCTWELEEDVDNDKIEQYLRFNKIPQRSEWKSKKRPHPELWKKLEKTPVYKGGNSLRPYQLEGLNWLKFSWYNTHNCILADEMGLGKTIQSLTFVHSVYEYGIRGPFLVIAPLSTIPNWQREFEGWTDMNVVVYHGSVTSKQMIQDYEYYYKTESGKVLKEPIKFNVLITTFEMIVTDYMDLKAFNWRLCVIDEAHRLKNRNCKLLEGLRQLNLEHRVLLSGTPLQNNISELFSLLNFLEPSQFSSQEEFMSEFGSLRTEEEVNKLQALLKPMMLRRLKDDVEKSLAPKEETIIEVELTNIQKKYYRGILEQNFSFLKKGTTSANIPNLMNTMMELRKCCIHPYLLNGAEEQIQYDFKSQHG-EDPESYYKNLILSAGKMVLIDKLLPKLKANGHRVLIFSQMVRCLDILEDYLVYRKYPFERIDGRIRGNLRQEAIDRYSKPGSDRFVFLLCTKAGGLGINLTAADTVIIYDSDWNPQNDLQAQARCHRIGQRKMVKIYRLLCRNTYEREMFDKASMKLGLDKAVLQSMNTQGSKDGNNKQLSKKEIEDLLKKGAYGAVMDDDNAGDKFCEEDIDSILKRRTQVITMESE-KGSTFSKASFAASGNRSDITIDDPDFWTKWAKKVDIDPDACERDETEDLVLSEPRRRTQIKRYGHEDVMELNSEESSNENSDEEGGIGLRSRRRKEKRDRAREKKGNDEYIPRERDALAALGLEEIQYGNWAKSECFKVEKGLLSFGWGRWSELLELGQFKRGWRDVDVEDCARIILLYCLQVYKGDEKIKTFIWDLITPTEDGEVQKISRDHSGLHNLVPRGRNGGKSNKESTGVSTPAPGSASGSNSGNTTPAHKSSALDGSDKDSGGINASAVAAAVTSIHDPNHWSKKEKYDADAYLEGAYKKHLGRHANKVLLRVRMLYYIQHEVIGDFVQQIKDNTPISELPIRPPPTPDQVPSSWWNPICCDKSLLVGTYKHGCEMYRQMRADPNLCFVTHVGAGAAGDDLAVTSLPINEDDANSKHDDGDEVDDDGTTTTKDSDSTKLTGGDNKDSLLDPERPSSSGKSSSENASGGNDKTESENDATTVSESSYKSEVLPGKGSDLDVSVAQQDALSATPELANTSDPKMNKNDAQVSASVSCDPADSSSPEAAGKAQGTGVQTGDAGELDIESEKKDNEKETKESTGDAPAVEAKKDSAAIARAEGDKTESCTNNATTNISTTTTTTTITNTTTTTNNPSSKAANSNNTTDHANSNSHLGLDEEESVAGSYPPTVAAVEDATTMWPSMQDLNTRLRRVITAYQRNYKKEELKLQQKAKLQALVSSTPPLSVPTTPTLQSMQMQLQSGSGSGGSGIGSSAQHDASGRSLQALMQSQGASTSAAAAAAASSAGGSCSGSGQVGMGGAGVMPAMPTAADISLMLSILNTTDVNQLANLDINKLAMYLVSMNNKMERQGKMELAAKERESQRLQLIPKKWNRREEYEFLRVLTGYGVDLHVSTPMASSNGSSLSPDWTKFKQMAHLERKSDETLTDYYKVFVAMCKRQAGLKLSESERGLEG--IIEEIEKEHAKLILDRLEVLAKLREVAR-NPMLEERLKLCTKNADTPDWWEPGRHDKELITAVLKHGLYRSETFIFNDPNFSFGESEKRFIRELEAQIQRTIKLEAFNAEKAEKLAAAEKDAATEKAAATEKAAAEKAASVKNEVIDLDDELMTNESVIKKESPVTPIKEEIKSEESPEKHDTADNLEDKNSDAEESTKIKGKEDFNPETTEKEALDESTNLNKDKSSTETLVPEIEDSKPSEDKMEVEELPVAENGEKEGSPEKCSDAEDKKFSEEKPSSPAVPDGKVSEMEADEAAPNTEENCSGDSESPEKECEDKVVEKVEEEKGENSYEKAEEQKEETEKLEKSSIESEPSEKSE---------TVLEPEVAVPKKSTGDQDILDLVAGPSDPDDDEVMKEKEKAVEEECKKQAAELKARFPDLEVIQPATVKQQKLEKPKLEMCMIRWFKDFALERRIAHIVACVESGNWPVDSKYSAFATCKGATDLSIALHESIPHLSSLERRSTTPDVITITTDQGVTKHLQTSHMQQVASSASAASTSSGVPQVTQSKPSSSNSLPGLDAKSINAAVAAAVAAAAAGGNATSLSSLLPGMSLSAATGSSAGGVSGLSVPSAGSGVGKKRKRHIAIDVETERAKLHALLNSSTMAPKDWESEIANMEALSGSSGRGR--------GGNSSASSGMQPPPAHQHASLSRQSSGQFSKPAVPAMKTPPPSMGAPMDLSSSLPKMNMTEMLKSASSSGAIDLSEVQDFSMPSKKSSVHAALSSAFPSMGNKSKLDDTLNKLMKKNNCTIEEPVIGKEKKRKKLDEIVLGLSAAKEQKTFPDPSLPSSKKPQIPPSVSVTPANLQSSSNQQSNQKPFTITVTTVPGKSKSGSSNSGSGTGGSSSASGGGAGGSGLSALQNMAMGGLSSKDSLNALLAQTMATDPQTFLKQQQK--MMQFLPPAQRKAYENMLAEMEQAMKISSKFSTNSPHDVKVNKWLSDMTSPLGDQLSIDYVGGGGASGSGSGNSRRSNRQQGNSQQSSSAAQLQKQQQQQQQQQQQQQQHSMPGPQNLTGEEPVPVINKQTGKRLGGNKAPQLKRLMQWLTENPNYEVDPKWLEQMQNPMSTPSPRPASMESGYGSSAVKSHGGRPLSNLSSTSSSSHTQQQSSAAQSQAGGNSGSSKKNSRQQTAASAALDQAALQFGSLAGLNPSLLANLPGLGAFDPKNPLAAFDPKNPLLSMSFGGMPGMGNIPGLGNLNNMNLFASLAGMGGLGNLAGMDTQSLAALMAAAGPTLGGLTGASGGAGSGKSQAQSQSSATSSSSSASKKKQQQQQQQAQNEAAQLAAAISASTGGSGASGGKNAAASASQLAAGFPFLFPNPSLLYPPMGLGGLNPYSLGSSGLGSAYDQLAQQYNLLNGATSSASNTSSTQSKSHQSQSKSSQSRNTTASANSAASLMNAMASMGGGASTVTTPSTSASGSGRGRQSSSRNQSQTTPTAADMAQLSSLLMPGADPHLLESLSRMSNMDLAQATRLMSSLGMPPLSGTPSSSGGGNTSTSKRSSQAANEANVQAKEQQKWLESLARGALPTDLAALQAFSQGKMPSTSGSNTGTSTSSSKSSKAAATAAAAQLPQIPGMSSDFPQAFLAEMAAQAMAAAGGSLPLSGPGSLASLAGLTGGSAGGGGSSASGSTSHSSSKRQREQDAFKQQMDYYTKTLGLGSGISLIPTSSAGGSSASSSAANAAAAAYAAALDAEQQHQQQQKALSKRARGDLHPTKEELAALAAGLPLNLGASMSSIEKSLRGGSSSSSSSTPAPMTAEQDKVTLTPLNASGGGSGSSSSSAAAAGLAANLPSQTTITIAPPISSGASTSSERSERSESRISLTITNAADAAKLPPPYEEADELIIQPILKKPTAANPGSSHGGSVDDLDTAENTSAANLSGSSSSSAAAAAAAAAEENRRSSNRLKRPRSGNEQGSGSVEGQPPEKRRELRSTRHTRSSADASTLNLSTGSESGAEERNE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::*::.: . .:: :. * :: : : .: .. . . * : . *:.* *. .:* *: : .: .. . : * :. : *: * : : .* * . :.: . :* .. :. . . .. :::*. . : ** :.:. . * *. .. : . . *. ****.*:.:*:** :*: ::. **: ** : * .. : :.:*: : . * :::: ::: :*: : :*: .:* ::* ::***********:* * *** * * *: **:**::**:* :** : ::: ** *: *:**:*::: .* :** ..****** **.**:.****:**** *:::: :: :* * * :** .: *:***.: *:..* ** *****:*** *.*** :****************::*: .:: *::****:*******.**:***. **:**.:***** *:*** :** :: .*: :. :**: :*******::* :** ::* :******************: : ***:***:******.:.**************.*: *:.***.*:***:*:***::***************.****:*****************.***:**:** **:.. *:***:********** ****:.****:* .*:. :. : .: : :* :***:********** *.**:**:***************: *:*.:******:****** ****:.* .**********:************* **:********************* * **:***: **:**********:*******:**.:* :*. :* :**** *:****:******:**::: *.********.**:***:.**::** *****:****.:****:**::***:** **** .::: :: *.*.**:. ** *.* ::*. : ** . .. :.:*:* *. * :. *: *. : ::***:***.** ******.::* *:** : *:* .* :*:**:: ****:***:***:****::**. * :.. **** *****:* * ::: . .. : .* . :..***** :*.************:: *::*: . : :. * :* : * . * .*****:*..*** * *. ***** ***: :** . * .. . : * *: . . :. ..* :: . .. . . . *.:****::* *** ::* : * . : . . : * : : *.***: :* *.::.:** . .. **::*: :::*::*:**.* *: **:**: . * :. : :: * :*:* * *:*:* *:** . * * **:** . * *** *:**::*: .. **** *:: :*:***::** :: :.: :. . . . : :. : . : . . : . . * : . ..: . .: . :. .. *. . : :. * : . : . :.. * . .: : * . : .. :. : . :. . : : : . .. *** :. : : . . . : : .. : : . . ::. .: . : . : . . : : : .. . . . . .: : . .. . :.. :. : *. . . . *. :* *. .: : :.. : .* : .. .*.* . : . * . . : :: : .: :: . * . * . : : . :: . . ... : . . . . . :. * . :* .* . * ...* : . : :: : . . . : . . :.... . :. .: :::: :. . : . :: :*:: : :: . . .* *** *..: ::.* * :.. : : .. . * : . . . . :*:.. :: . :..** .* : .* .* *: * . * .: : : :. : :*::: . : : : :.. . ...: :* * * . : . .. : . .. .:*.. ::.. :..:*:** . *: . :. :.:*.: : : .: : . . : . . . . : .. ..... : : .: ", "identical_positions": 738, "similar_positions": 782, "identity": "13.31%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-562", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q00900-1", "uniprot_id": "ZEP2_RAT", "id": "Q00900-1", "name": "Human immunodeficiency virus type I enhancer-binding protein 2 homolog", "aln": "--------MDTGDTALGQKATSRSGETDSVSGRWRQEQSAGLKMSTFSSQEGQRQPQIDPDQIGNVASAQLFGSGKLASPGEGVHQVTEKQYPPHRPSPYPCQHSLSFPQHSLPQGMMHSNKPHQSLEGPPWLFSGPLPSVASEDLFPFPMHGHSSGYPRKKISSLNPAYSQYSQKSIEQAEDAHKKEHKPKKPGKYICPYCSRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHAHAIKAG------LVPFTESSVSKLDLEAGFIDVEAEIHSDGEQSTDTDEESSLFAEASDKVSPGPPIPLDIASRGGYPGSLEESLGGPMKVPILIIPKSGIPLPNEGSQYLGPDMLPNPSLNAKADDSHTVKQKLALRLSEKKGQDS--------EPSLNLLSPHSKGSTDSGYFSRSESAEQQISPPNTNAKSYEEIIFGKYCRLSPRNTLSVTPTGQERTAMGRRGLVEPLPHVNTRLEVKMFEDPITQLIPSKGEMD-------PSQVNMLKTTKFNSECRQPQAMAASVRNEGKPYPGSFPGSNPILLEAPVDSSPLIRSNSMPTSSATNLSIPPSLRGSHSFDERMTGSDDVFYPGTVGIPPQRMLRRQAAFELPSVQEGHMEFEHPARVPKILAGSSLKEKKLVPGDRSGYDYDACRKPYKKWEDPETPKQSYRDISCLSTFKHGGEYFMDPSVPLPGVPTMFGTTCENRKRRKEKSVGDEEDTPMICGGMGSAPGSMMSSEYDSKLQ--DGGRSGFTMTGHESLPHGYSDRLDLARPQLPSRSPSLGSEDLPSAGDPDKMTDLG-KKPPGNVISVIQHTNSLSRPNSFERSESTEMAVSTQDKTPSPSEMGDSEVLEGPVSPEWAPPGDGAESGSRPTPSQQVPQHSYHGQPRLVRQHNIQVPEIRVTEEPDKPEKEKEAPTKEPEKPVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADMEHSSGESSFESTGTGLSRSPSQESNLSHSSSFSMSFDRDETVKLTAPPKQDESGKHSEFLTVPAGSYSLSVPGHHHQKEMRRCSSEQMPCPHPTEVPEIRSKSFDYGNLSHAPVAGASPSTLSPSRERKKCFLVRQASFSGSPEIAQGEAGMDPSVKQEQLEQLHAGLRAAWTT----VLPPLPGDDPGKQVVGPCGQLSSGPPLHLAQQQIMHMDSQESLRNPLIQPTSYMTGKHLPEQPHLFPHQDAVPFSPIQNALFQFQYPTVCMVHLPAQQPPWWQAHFPHPFTPHPQNSYSKPPFQADIHSSYSLEHVAEHTGKKSADYPHAKEQTYPCYSGASGLHSKNLPPKFPSDPGSKS--TEAPPTEQLLREDFASENAGPLQSLPGTVVPVRIQTHVPSYGSVMYTSISQILGQNSPAIVICKVDENMTQRTLVTNAAMQGIGFNIAQVLGQRTGLEKYPLWKVPQTLPLGLESS------IPLCLPS---TSDSAASLGGSKRMLSPASSLELFMETKQQKRVKEEKMYGQIVEELSAVELTNSDIKKGLSRPQKPQLVRQGCASEPKDGSSQSRSSSFSSLSPSSSQDHPAASG----PFPPNREILSGSRAP-----PRRKFSGPSESRESSDELDIDETSSDMSMSPQSSSLPTGGSQQEDEGKARKLPVSMLVHMASGPGGNVANSTLLFTDVADFQQILQFPSLRTTTTVSWCFLNYTKPNFVQQATFKSSVYASWCISSCNPNPSGLNTKTTLALLRSKQKITA--EIYTLAAMHRPGTGKLTSSSAWKQFAQMKPDAPFLFG-NKLERKLGGNVLKERGKGEIHGDKDLGSKQTEPIRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKLCNFAFKTKGNLTKHMKSKAHMKKCLELGVSMTSVDET-----ETEEAENMEDLHKTSEKHSMSGISTDHQFSDAEESDGEDGDDNDEDDEDDDDFDDQGDLTPKTRSRSTSPQPPRFSSLPVNVGAVAHGVPSDSSLGHSSLISYLVTLPSIQVTQLMTPSDSCEDTQMTEYQRLFQSKSTDSEPDKDRLDIPSSMDEEAMLSSEPSSSPRDFSPSSYRSSP------------GYDSSPCRDNSPKRYLIPKGDLSPRRHLSPRRDLSPMRHLSPRKEAALRREMSQGDASPRRHLSPRRPLSPGKDITTRRDLSPRRERRYMTTIRAPSPRRA-------------LYHN-PPLPMGQYLQTEPIVLGPPNLRRGLPQVPYFSLYGDQEGAYEHHGSSLFPEGPTDYVFSHLPLHS-----QQQVRAPIPMVPVGGIQMVHSLPPAISGLHPPPTLPLPTEGSEEKKGAPGEALTQDPYTLSRRHEKQAPHVLQSSGLPSSPSSPRLLMKQSTSEDSLNSTEREQEENIQTCTKAIASLRIATEEAALLGADQPTWVQESPQKPLESAHISIR--------------------------HFSGPEPGQLCTSAAHPDLHDGEKDTFG-TSQTAVAHPTFYSKGSVDEKQVDFQSSKELSLSTEEGNEPSSEKNRLH----------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UHF7-1", "uniprot_id": "ZEP2_MOUSE", "id": "Q3UHF7-1", "name": "Transcription factor HIVEP2", "aln": "--------MDTGDTALGQKATSRSGETDSVSGRWRQEQSAVLKMSTFSSQEGPRQPQIDPEQIGNAASAQLFGSGKLASPGEGLHQVTEKQYPPHRPSPYPCQHSLSFPQHSLSQGMTHSHKPHQSLEGPPWLFPGPLPSVASEDLFPFPMHGHSGGYPRKKISNLNPAYSQYSQKSIEQAEDAHKKEHKPKKPGKYICPYCSRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHAHAIKAG------LVPFTESSVSKLDLEAGFIDVEAEIHSDGEQSTDTDEESSLFAEASDKVSPGPPVPLDIASRGGYHGSLEESLGGPMKVPILIIPKSGIPLASEGSQYLSSEMLPNPSLNAKADDSHTVKQKLALRLSEKKGQDS--------EPSLNLLSPHSKGSTDSGYFSRSESAEQQISPPNTNAKSYEEIIFGKYCRLSPRNTLSVTPTGQERTAMGRRGIMEPLPHLNTRLEVKMFEDPISQLNPSKGEMD-------PGQINMLKTTKFNSECRQPQAIPSSVRNEGKPYPGNFLGSNPMLLEAPVDSSPLIRSNSMPTSSATNLSVPPSLRGSHSFDERMTGSDDVFYPGTVGIPPQRMLRRQAAFELPSVQEGHMESEHPARVSKGLASPSLKEKKLLPGDRPGYDYDVCRKPYKKWEDSETLKQSY-----LGSFKQGGEYFMDPSVPVQGVPTMFGTTCENRKRRKEKSVGDEEDVPMICGGMGNAPVGMMSSEYDPKLQ--DGGRSGFAMTAHESLAHGHSDRLDPARPQLPSRSPSLGSEDLPLAADPDKMTDLG-KKPPGNVISVIQHTNSLSRPNSFERSESTEMVACPQDKTPSPAETCDSEVLEAPVSPEWAPPGDGGESGSKPTPSQQVPQHSYHAQPRLVRQHNIQVPEIRVTEEPDKPEKEKEAPTKEPEKPVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADLEHSSGESSFESTGTGLSRSPSQESNLSHSSSFSMSFDREETVKLTAPPKQDESGKHSEFLTVPAGSYSLSVPGHHHQKEMRRCSSEQMPCPHPTEVPEIRSKSFDYGNLSHAPVAGTSPSTLSPSRERKKCFLVRQASFSGSPEIAQGEAGVDPSVKQEHMEHLHAGLRAAWSS----VLPPLPGDDPGKQ-VGTCGPLSSGPPLHLTQQQIMHMDSQESLRNPLIQPTSYMTSKHLPEQPHLFPHQDAVPFSPIQNALFQFQYPTVCMVHLPAQQPPWWQTHFPHPFAPHPQNSYSKPPFQADLHSSYPLEHVAEHTGKKSADYPHAKEQTYPCYSGTSGLHSKNLPLKFPSDPGSKS--TETP-TEQLLREDFASENAGPLQSLPGTVVPVRIQTHVPSYGSVMYTSISQILGQNSPAIVICKVDENMTQRTLVTNAAMQGIGLNIAQVLGQHTGLEKYPLWKVPQTLPLGLESS------IPLCLPS---TSDNAASLGGSKRMLSPASSLELFMETKQQKRVKEEKMYGQIVEELSAVELTNSDIKKGLSRPQKPQLVRQGCASEPKDGCFQSRSSSFSSLSPSSSQDHPSASG----PFPPNREILPGSRAP-----PRRKFSGPSESRESSDELDMDETSSDMSMSPQSSALPTGGGQQEEEGKARKLPVSMLVHMASGPGGNVANSTLLFTDVADFQQILQFPSLRTTTTVSWCFLNYTKPSFVQQATFKSSVYASWCISSCNPNPSGLNTKTTLALLRSKQKITA--EIYTLAAMHRPGAGKLTSSSVWKQFAQMKPDAPFLFG-NKLERKLAGNVLKERGKGEIHGDKDLGSKQTEPIRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKLCNFAFKTKGNLTKHMKSKAHMKKCLELGVSMTSVDDT-----ETEEAENMEELHKTSEKHSMSGISTDHQFSDAEESDGEDGDDNDDDDEDDDDFDDQGDLTPKTRSRSTSPQPPRFSSLPVNVGAVAHGVPSDSSLGHSSLISYLVTLPSIQVTQLMTPSDSCDDTQMTEYQRLFQSKSTDSEPDKDRLDIPSSMDEEAMLSSEPSSSPRDFSPSSYRSSP------------GYDSSPCRDNSPKRYLIPKGDLSPRRHLSPRRDLSPMRHLSPRKEAALRREMSQGDASPRRHLSPRRPLSPGKDITARRDLSPRRERRYMTTIRAPSPRRA-------------LYPN-PPLSMGQYLQTEPIVLGPPNLRRGIPQVPYFSLYGDQEGAYEHHGSSLFPEGPTDYVFSHLPLHS-----QQQVRAPIPMVPVGGIQMVHSLPPALSGLHPPPTLPLPTEGSEEKKGAPGEAFAKDPYILSRRHEKQAPQVLQSSGLPSSPSSPRLLMKQSTSEDSLNSTEREQEENIQTCTKAIASLRIATEEAALLGADPPTWVQESPQKPLESAHVSIR--------------------------HFGGPEPGQPCTSAAHPDLHDGEKDTFG-TSQTAVAHPTFYSKSSVDEKRVDFQSSKELSLSTEEGNEPSPEKNQLH----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31629-1", "uniprot_id": "ZEP2_HUMAN", "id": "P31629-1", "name": "Transcription factor HIVEP2", "aln": "--------MDTGDTALGQKATSRSGETDKASGRWRQEQSAVIKMSTFGSHEGQRQPQIEPEQIGNTASAQLFGSGKLASPSEVVQQVAEKQYPPHRPSPYSCQHSLSFPQHSLPQGVMHSTKPHQSLEGPPWLFPGPLPSVASEDLFPFPIHGHSGGYPRKKISSLNPAYSQYSQKSIEQAEEAHKKEHKPKKPGKYICPYCSRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHAHAIKAG------LVPFTESAVSKLDLEAGFIDVEAEIHSDGEQSTDTDEESSLFAEASDKMSPGPPIPLDIASRGGYHGSLEESLGGPMKVPILIIPKSGIPLPNESSQYIGPDMLPNPSLNTKADDSHTVKQKLALRLSEKKGQDS--------EPSLNLLSPHSKGSTDSGYFSRSESAEQQISPPNTNAKSYEEIIFGKYCRLSPRNALSVTTTSQERAAMGRKGIMEPLPHVNTRLDVKMFEDPVSQLIPSKGDVD-------PSQTSMLKSTKFNSESRQPQIIPSSIRNEGKLYPANFQGSNPVLLEAPVDSSPLIRSNSVPTSSATNLTIPPSLRGSHSFDERMTGSDDVFYPGTVGIPPQRMLRRQAAFELPSVQEGHVEVEHHGRMLKGISSSSLKEKKLSPGDRVGYDYDVCRKPYKKWEDSETPKQNYRDISCLSSLKHGGEYFMDPVVPLQGVPSMFGTTCENRKRRKEKSVGDEEDTPMICSSIVSTPVGIMASDYDPKLQMQEGVRSGFAMAGHENLSHGHTERFDPCRPQLQPGSPSLVSEESPSAIDSDKMSDLGGRKPPGNVISVIQHTNSLSRPNSFERSESAELVACTQDKAPSPSETCDSEISEAPVSPEWAPPGDGAESGGKPSPSQQVQQQSYHTQPRLVRQHNIQVPEIRVTEEPDKPEKEKEAQSKEPEKPVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADMEHSSGESSFESTGTGLSRSPSQESNLSHSSSFSMSFEREETSKLSALPKQDEFGKHSEFLTVPAGSYSLSVPGHHHQKEMRRCSSEQMPCPHPAEVPEVRSKSFDYGNLSHAPVSGAAASTVSPSRERKKCFLVRQASFSGSPEISQGEVGMDQSVKQEQLEHLHAGLRSGWHHGPPAVLPPLQQEDPGKQVAGPCPPLSSGP-LHLAQPQIMHMDSQESLRNPLIQPTSYMTSKHLPEQPHLFPHQETIPFSPIQNALFQFQYPTVCMVHLPAQQPPWWQAHFPHPFAQHPQKSYGKPSFQTEIHSSYPLEHVAEHTGKKPAEYAHTKEQTYPCYSGASGLHPKNLLPKFPSDQSSKS--TETP-SEQVLQEDFASANAGSLQSLPGTVVPVRIQTHVPSYGSVMYTSISQILGQNSPAIVICKVDENMTQRTLVTNAAMQGIGFNIAQVLGQHAGLEKYPIWKAPQTLPLGLESS------IPLCLPS---TSDSVATLGGSKRMLSPASSLELFMETKQQKRVKEEKMYGQIVEELSAVELTNSDIKKDLSRPQKPQLVRQGCASEPKDG-LQSGSSSFSSLSPSSSQDYPSVSPSSREPFLPSKEMLSGSRAPL----PGQKSSGPSESKESSDELDIDETASDMSMSPQSSSLPAGDGQLEEEGKGHKRPVGMLVRMASAPSGNVADSTLLLTDMADFQQILQFPSLRTTTTVSWCFLNYTKPNYVQQATFKSSVYASWCISSCNPNPSGLNTKTTLALLRSKQKITA--EIYTLAAMHRPGTGKLTSSSAWKQFTQMKPDASFLFG-SKLERKLVGNILKERGKGDIHGDKDIGSKQTEPIRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKLCNFAFKTKGNLTKHMKSKAHMKKCLELGVSMTSVDDT-----ETEEAENLEDLHKAAEKHSMSSISTDHQFSDAEESDGEDGDDNDDDDEDEDDFDDQGDLTPKTRSRSTSPQPPRFSSLPVNVGAVPHGVPSDSSLGHSSLISYLVTLPSIRVTQLMTPSDSCEDTQMTEYQRLFQSKSTDSEPDKDRLDIPSCMDEECMLPSEPSSSPRDFSPSSHHSSP------------GYDSSPCRDNSPKRYLIPKGDLSPRRHLSPRRDLSPMRHLSPRKEAALRREMSQRDVSPRRHLSPRRPVSPGKDITARRDLSPRRERRYMTTIRAPSPRRA-------------LYHN-PPLSMGQYLQAEPIVLGPPNLRRGLPQVPYFSLYGDQEGAYEHPGSSLFPEGPNDYVFSHLPLHS-----QQQVRAPIPMVPVGGIQMVHSMPPALSSLHPSPTLPLPMEGFEEKKGASGESFSKDPYVLSKQHEKRGPHALQSSGPPSTPSSPRLLMKQSTSEDSLNATEREQEENIQTCTKAIASLRIATEEAALLGPDQPARVQEPHQNPLGSAHVSIR--------------------------HFSRPEPGQPCTSATHPDLHDGEKDNFG-TSQTPLAHSTFYSKSCVDDKQLDFHSSKELSSSTEESKDPSSEKSQLH----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PEH8-1", "uniprot_id": "A0A8M9PEH8_DANRE", "id": "A0A8M9PEH8-1", "name": "", "aln": "-----------------MEATKTSGEVESSE-----------QIISFKDDE-------------KHLPSEMTQRGQSSGSEDKIRLAEQPQTPSVSPSP-------GIEPQVLASGNTLTSKSKEQSHVQLRRKNVPLPNKR----------------------YLQAEYEMLSG-------GLHKKEQKSVKTGKYVCQYCGRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHTHAVKAG------LVSVSEQDCKNTDEVA-----EGEMHSDAEQSSDTDEEVAEDLSL-DTTSHIKETEGYVQEKVGKLAKKEALFPSQTPLKKETGPSGKVSL----WQFREMTAPVAIAQIDQMVEFSTIKQKLALRLSEKKSQES--------DQSLSLPSSYSKGSTDSGYFSRSESAEQQINQSSASAKSYQEIMFGKCYRPATRPKQSIT------VQTCMTDINEATSSFMITLNKGMMPG------DTDSSIH-------RSKKDLVRSIKIDSESFQ----------EEDYQECQIPSSD--LLETALESSVFLRSNSLPTSSKSNLNTPQGLRSSNSFDERMTG-ADVTYRGAMGM---RRLMRQSAFEH-SANEGHAESDCYTHLACSLKS-----------DLKIHSIDDSKMAAENFQETET----------------------------CSVCPGHSSESSTRKRRKDKTVTEEED---------------------------------FHIQDKPSNVTGLSEDLETK--QISSDSVVSDTER----------------KAGSNVISVIQHTNSLNRLNSAEKLS--EVRSHQLDKIG--------KFMEKGHSMECHRTGSECQWG-----PCGFLHQKLHMHKQPTSQPNIQVPEIRVTVEPDRPEKVPDVGVKQREKHTEEFQWPQRSETLSQFPMEKLPPKKKRLRLAEMECSSGESSFESACTSLSRSPSQDSNLSHSSSFSQSLDREETLNLVSQINPDESSKPLEFLSVPGSS-------QSHHREMRRSASEQAPYKLPSEIAEFRSKSFDYGSLSPS-----STYRLEEVKERRRAFLVRQASLSGEPETQGGNFSDEISKRT----TLPFTPE----------------------------------------------GSIEKMRYSLISGSS-------------FPHHR--QYSPVQ-SSSQHVKPTVCNVH--------------------------------DMENVMLVIKKEPEESKSPETYVNLREPQEDCSQSLG-----NVLSTIAVLSQAQQ--ALAS------------------QCSSGLLVPVRIQMQVPSYGNITYTSISHILDSHIQKPISCLEHKKSSSQSQQ---------------------------LHSLQASPAKLKTG------IPLSLTSKTISTTEAPSGGANKRMLSPASSIELFIEAKQQKRVKDENIYGQIVEELSAVELGNLEVEK------------------------ESPKSEFTS-EPIDKMDMDEATQ----EFYSNAELQSSARIS-----------------QDAAIMEQKPTPESMMASHHS--------------------ASCISLMPSAITG-----TLLFS---------KFPGLHTTTCMSWCYLNTTKPNSTHTVAPFS-EYASWFVRCHNPNPPDISTGMVLALLRSKQQRQN--AIYTIATIYQP--GLLVTSTPWTPKQEQIALDYREED-TKQDIRLR--EISHRGKS-LREDVSSIIRQTEPMRVKIFEGGYKSNEEYVYVRGRGRGKYICEECGIRCKKPSMLRKHIRTHTDVRPYICKCCNFAFKTKGNLTKHMKSKAHMKKCLELGVSPTAMDNT-----EDADDTQKSLGIMPAEQT------IKHQFSDVEDSDGADEDEPDEDEDDE----CDGDSTPKTLSRSTSPQ-----SYAVNKPCMSGCLPKHFDSGCN--------LP------------------------------------KEQLEA-SSLTIEDDLNSDQSSCSFELCPPQLLS-------------------PCWDSPRQRYMSPRGDLSPQRHLLSSRDSSPLRAVSPRRDLSIR-----GDFSPIRQLSPVRPT--GLDTSGQRAQSPLG--RHKVALRAVSPRRG-------------SYQHRTHMDLGRSVRFQASPIRPIIGETGVDQG---DTSLNLIVPVGLCSSKDLPKTRQPDIFSHLPLHS-----QGQVSTPVPMVPIGVLRMPS--ISTSGAVAERNSLPSIPQGNILETAAPGQTSASVP----------DPAVAYSG-------------EIATYSTGLPNKDDKKEESVYTCAKAIASLRITSEDAS--------------DNPPKS-----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z8F4-1", "uniprot_id": "SCHNR_DROME", "id": "A1Z8F4-1", "name": "Protein schnurri", "aln": "MARRKGSGRGKSTVNSRKSALETAREKTKDEPTANTSQDNKFDNNMENATTTTAKHYKTAGKQYKTNKVNNTRRATAAAAAAAAAAATTTVTTAATPTKKRTYRETATATIVTQRSTNKANIAAAIALAAATEATASASASATATATDATLTASKAAATAAATTDAASGNSNSSSKPSTSTRDKLGEVPLPTVDSNHIISNNNNNNNNNNTSNNNNNNHHSDNSISENNYEFKSRDKASLSDSKMTLQQMAAVSSNQEPVAPNVANTMSNSSIINSQQTTVNATPATDEAPLGDRSNISRYLHKKFKRLASTTEVDSWSATNGGGALQASGDAVRTTSLSSNSSLSPPPTTPLANGHHLMTQQQSHQQVQQQQQQQQTPPPSVAIHEFSANFVNSNHVNAIGHEESIISNSGYKAAGRTRTPLANSNSNTNSTSNSNSNHAANATLSPASFAQHQQLTQPTTVSPGIPGGAAAPNPACEKSGRYVCQYCNLICAKPSVLEKHIRAHTNERPYPCDTCGIAFKTKSNLYKHCRSRSHAARARGLEVPADADDGLSDQDAELSNSSSELPSRAGSPYEEPINSPTPSPSTLSAAKSAYIQQPPLPTYMQQLPLGSPAAGTLPPTTADNHHSATAQHRQSIDYKPYKPKFHNASLYSCSSKELQQQQQQLQIQQQQQQHQLAQQKLS---------------------IQLPLVQQPSLAHPTLSPSTQMKMKHHINSHQIQLQLQQQQSLLAQQSLLAAMPPGGVYYLGQPSYYNQDTAAAIHQHALAIQQFQIHLAQQQQQQQQQHPPLVKATPPMQQPPSLPPQQLVRANSQISSVATAPATPTPAANLSTFASSSGGKQVNVAKVQEHISKLISQNEAIVENKEILLQKKYPKQLSRSRSFNNANSNNASQHGSNASALHANNSQNNTN--AQMPERETKVNLAQAIFQKQQHQLQQQQQQQITQQQQQQLEQQNYYTYIQQQQECQQQQLEPPNGVVKRNAYKPGVVMTTPVKQQQQLPPPPSP-LPMQTMQYRQDPATPVTKIEQPTTAVPVMPLNLSAKPKPTLVTVPVSSLSTSSLAPTPTTSTNPTSSSKTAPPPAQVNNSIIKNLLLNARGLAVPIGEGDDAVYSCPICASEFRSADDLKLHN----STYCQDASSSAPMSPASSPFRSNSISLSLPELKSHMANSKNPLSLAKLAWSQLKTKRSSLVLSRLSAAQTPARTSTVTAPTVTASAPAPAVATVTAPSSAPAPQIEALRFVDAPLPSPGPLLGKTPLVDYAQQSTPRKAQDSVVITKMHEDRQFVIEAQPAKRIKTSDLVVASSSQQPTSFNFSFNNQNSSNSVPELQSSKEERLRRFTSSGGSMIPISECPDLDNSPKMIRTPLLSGGSFQDVSVKVNNETGSSSKERKLMALVSGSGLLGVSSGPQHFQFPPINSITAFNPLTLPPMSGGDKTTPVTPIPHVPGMPGPGSLTPQMPLLPPPPQQLQLPIPSSRGRSPNRKQPSPLLLGGGSGELKALSPFGGVQNVPSEFSRQPPTPAQRQALQWNSKEAPKKAPFNFLRMADNVKTTEPEVRHFNLENVISGKQQELPLTPLHVDTPNGNAPEETSPVASASASAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNG-----HAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKLKQVMALYDSRQRMLGNGSSTAMAGSGKLSYNLVASQQIVSSPSTSSTSSAFYQGPLKTPPTVTIAALSEANVAAKANEEAQAKKLETSPSGQPLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPPDSEFLDVDMDFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRQKEHEAARGLLSLSMTPPIPQSVSPYP-QLQDTPLPAASPANSIGSSGSQPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKRSVANEESAPMDLTKPRGSILLISPSPVSVPAHDLPKSQAQQMHDVIFGTSGNESGFMKTLISVSDKVRISAEMEEQAKHEAEGEDVQLQTYIKEHALHQAKIKQSQFSRSYLINTLYTAASPVMSSSSTLFTANSRPVMSVNEVPSIEVHEVKTPEAIESPRSAPEQAPVILAQIAQEENEEPNIAEPHNANLPAAVQQPDVNEFTGVLGNPTAPPTSSVTATSVSTTTAAPVAPSSTANSTQPAQRTVIVGEDGFKSSTPTSKSGDLQHVSYGRGVPPAPIAGDARPTCTMCSKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLQEKDPGKLSSYTTPSGMMQLAQDAAGPVSQDSASEDGFSAAIASAIASLDNDSAGNTPKRASSMSEDETVANGLNHSLKRRLPGSFSSTGEESDNPPESSGEKRARSGQELPVPVAVPVAASAAASN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* . : * . . . : : . :.. . .. *: . . : . . . . . * : . .::: .. : .. ::: ..* .:.. . *. : *:.* . : : : .. .:: .. : :. :* * .: . . : . * . . : . . :. : : * .:*:: . : :* : *: * :. .. ::.*:* :. . ..:. : : .. : : . * : . . : . :: ... . * . ..: *. . .. ... . : * * .::* : . .:* * :* : *. * : : . : . : : :: :. . . . .: * * :..: : : :: :: . : . * : * :. . : . . .. : . * .. : : : . . * . :.. ::.. . :..: : :: : : : ::.. *.* :::. :::: : : :.. *. *. . . .. ::.... : .: :* . . : :: *. . * * : : . *.* . : : :. : ...:: . : *: . : .* : : . : :. . : *.: . *: . . : . .. : . . :: . :. : : .. .: . *. .. : :*. : .:: . : * * . *: . : . :*.*... : ...: * :.: . :: .: ** . :* .: .: : . :: .. : : : . . :... * .. * :. : .*: :* : :* :* .:*. . * . :*:* .:. .:** *:*: ::* : . :.:. . . . * : :.. . . : : . : : ***:*:*:*.*:******:*:*.************:***********: *. ***:***********:**:*:***:***:. .: : : . .. ..::** *.... :. . :.:.: . . . .:*.** . .: . . : . . * : : * . . .* . :: : . : : ..*: : : : ..: . : ** *. . . .. . .. *** . . . : : . . * . . . :. * * * : : . :. * * :: . . : * : : . . .: *:.. ::** . * :: . ", "identical_positions": 165, "similar_positions": 531, "identity": "6.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-563", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14517-1", "uniprot_id": "FAT1_HUMAN", "id": "Q14517-1", "name": "Protocadherin Fat 1", "aln": "---------------------MGRHLALLLLLLLLFQHFGDSDGSQRLEQTP-------LQFTHLEYNVTVQENSAAKTYVG--HPVKMGVYITHPAWEVRYKIVSGDSENLFKAEEYILGDFCFLRIRTKGGNTAILNREVKDHYTLIVKALEKNTN-----VEARTKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTNGEFYYSFKDRTDMFAIHPTSGVIVLTGRLDYLETKLYEMEILAADRGMKLYGSSGISSMAKLTVHIEQANECAPVITAVTLSPSELDRD-PAYAIVTVDDCDQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGGIDWDSHPFGYNLTLQAKDKGTPPQFSSVKVIHVTSPQFKAGPVKFEKDVYRAEISEFAPPNTPVVMVKAIPAYS--HLRYVFKSTPGKAK--FSLNYNTGLISILEPVKRQQAAHFELEVTTSDRK-------ASTKVLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTVMSLSAVDPDEGENGYVTYSIANLNHVPFAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWGLPYRREVEVLATITLNNLNDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADELQLVQYQIEAGNELDFFSLNPNSGVLSLKRSLMDGLGAKVSFHSLRITATDGENFATPLYINITVAASHK---------LVNLQCEETGVAKMLAEKLLQANKLHNQGEVEDIFFDS------HSVNAHIPQFRSTLPTGIQVKENQPVGSSVIFMNSTDLDTGFNGKLVYAVSGGNEDSCFMIDMETGMLKILSPLDRETTDKYTLNITVYDLGIPQKAAWRLLHVVVVDANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKDLGPNGHVTYSIVTDTDTFSIDSVTGVVNIARPLDRELQHEHSLKIEARDQAREEPQLFSTVVVKVSLEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHGEGN--FDVDKLSGAVRIVQQLDFEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDED-ARRDGEIRYSIRDGSGVGVFKIGEETGVIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSSNDKLMYKITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSPPKSTIARVIVKILDENDNKPQFLQKFYKIRLPEREKPDRERNAR-REPLYHVIATDKDEGPNAEISYSIEDGNEHGKFFIEPKTGVVSSKRFSAAGEYDILSIKAVDNGRPQKSSTTRLHIEWISKPKPSLEP--ISFEESFFTFTVMESD-PVAHMIGVISVEPPGIPLWFDITG----------------------GNYDSHFDVDKGTGTIIVAKPLDAEQKSNYNLTVEATDGTTTILTQVFIKVIDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDEKNKLIYTLQSSRDPLSLKKFRLDPATGSLYTSEKLDHEAVHQHTLTVMVRDQDVPVKRNFARIVVNVSDTNDHAPWFTASSYKGRVYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNSFMIDPVLGSIKTAKELDRSNQAEYDLMVKATDKGSPPMSEITSVRIFVTIADNASPKFTSKEYSVELSETVSIGSFVGMVTAHSQSSVVYEIKDGNTGDAFDINPHSGTIITQKALDFETLPIYTLIIQGTNMAGLSTNTTVLVHLQDENDNAPVFMQAEYTGLISESASINSVVLTDRNVP---LVIRAADADKDSNALLVYHIVEPSVHTYFAIDSSTGAIHTVLSLDYEETSIFHFTVQVHDMGTPRLFAEYAANVTVHVIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDADSSAFSQLIYSITEGNIGEKFSMDYKTGALTVQNTTQLRSR----YELTVRASDGRFAGLTSVKINVKESKESHLKFTQDVYSAVVKENSTEAETLAVITAIGNPINEPLFYHILNPDRRFKISRTSGVLSTTGTPFDREQQEAFDVVVEVTEEHKP-----SAVAHVVVKVIVEDQNDNAPVFVNLPYYAVVKVDTEVGHVIRYVTAVDRDSGRNGEVHYYLKEHHEHFQIGPLGEISLKKQFELDTLNKEYLVTVVAKDGGNPAFSAEVIVPITVMNKAMPVFEKPFYSAEIAESIQVHSPV-VHVQANSPEGLKVFYSITDGDPFSQFTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLTGAHAEVFVDIIVDDINDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSEPNRGISYQMFGNHSK-SHDHFHVDSSTGLISLLRTLDYEQSRQHTIFVRAVDGGMPTLSSDVIVTVDVTDLNDNPPLFEQQIYEARISEHAPHGHFVTCVKAYDADSSDIDKLQYSILSGNDHKHFVIDSATGIITLSNLHRHALKPFYSLNLSVSDGVFRSSTQVHVTVIGGNLHSPAFLQNEYEVELAENAPLHTLVMEVKTTDGDSGIYGHVTYHIVNDFAKDRFYINER-GQIFTLEKLDRETPAEKVISVRLMAKDAGGKVAFCTVNVILTDDNDNAPQFRATKYEVNIGSSAAKGTSVVKVLASDADEGSNADITYAIEADS--ESVKENLEINKLSGVITTKESLIGLENEFFTFFVRAVDNGSPSKESVVLVYVKILPPEMQLPKFSEPFYTFTVSEDVPIGTEIDLIRAEHSGTVLYSLVKGNTPESNRDESFVIDRQSGRLKLEKSLDHETTKWYQFSILARCTQDDHEMVASVDVSIQVKDANDNSPVFESSPYEAFIVENLPGGSRVIQIRASDADSGTNGQVMYSLDQSQS-VEVIESFAINMETGWITTLKELDHEKRDNYQIKVVASDHGEKIQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDD-PQGGVIAILSTTDADSEEINRQVTYFITGGDPLGQFAVETIQNEWKVYVKKPLDREKRDNYLLTITATDGTFSSKAIVEVKVLDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDADIRSNAEITYTLLGSGAEKFKLNPDTGELKTSTPLDREEQAVYHLLVRATDGG--GRFCQASIVLTLEDVNDNAPEFSADPYAITVFENTEPGTLLTRVQATDADAGLNRKILYSLIDSADGQFSINELSGIIQLEKPLDRELQAVYTLSLKAVDQGLPRRLTATGTVIVSVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSIISGNEHGKFSIDSKTGAVFIIENLDYESSHEYYLTVEATDGGTPSLSDVATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVITVMADDADGPSNSHIHYSIIDGNQGSSFTIDPVRGEVKVTKLLDRETISGYTLTVQASDNGSPPRVNTTTVNIDVSDVNDNAPVFSRGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGPPFFFTIVTGNDEKAFEVNPQGVLLTSSAIKRKEKDHYLLQVKVADNGKPQLSSLTYIDIRVIEESIYPPAILPLEIFITSSGEEYSGGVIGKIHATDQDVYDTLTYSLDP------QMDNLFSVSSTGGKLIAHKKLDIGQYLLNVSVTDGKFTTVADITVHIRQVTQEMLNHTIAIRFANLTPEEFVGDYWRNFQRALRNILGVRRNDIQIVSLQ---------------SSEPHPHLDVLLFVEKP-----GSAQISTKQLLHKINSSVTDIEEIIGVRILNVFQKLCAG--LDCPWKFCDEKVSVDESVMSTHSTARLSFVTPRHHRAAVCLCKE----GRCPPVHHGCEDDPCPEGSECVSDPWEEKHTCVCPSGRFGQCPGSSS---------------MTLTGNSYVKYRLTENENKL----EMKLTMRLRTYSTHAVVMYARG-TDYSILEIHHGRLQYKFDCGSGPGIVSVQSIQVNDGQWHAVALEVNGNYARLVLDQVHTASGTAPGTLKTLNLDNYVFFGGHIRQQGTRHGRSPQVGNGFRGCMDSIYLNGQELPLNSKP-----RSYAHIEESVDVSPGCFLTATEDCASNPCQNGGVCNPSPAGGYYCKCSALYIGTHCEISVNPCSSKPCLYGGTCVVDN-GGFVCQCRGLYTGQRCQLSPYCKDEPCKNGGTCFDSLDGAVCQCDSGFRGERCQSDIDECSGNPCLHGALCENTHGSYHCNCSHEYRGRHCED--AAPNQYVSTPWN----IGLAEGIGIVVFVAGIFLLVVVFVLCRKMISRKKKHQAEPKDKHLGPATAFLQRPYFDSKLNKNIYSDIPPQVPVRPISYTPSIPSDSRNNLDRNSFEGSAIPEHPEFSTFNPESVHGHRKAVAVCSVAPNLPPPPPSNSPSDSDSIQKPSWDFDYDTKVVDLDPCLSKKPLEEKPSQPYSARESLSEVQSLSSFQSESCDDN------------GYHWDTSDWMPS--VPLPDIQEFPNYEVIDEQTPLYSADPNAIDTDYYPGGYDIESDFPPPPEDFPAADELPPLPPEFSNQFES--IHPPRDMPAAGSLGSSSRNRQRFNLNQYLPNFYPLDMSEPQTKGTGENSTCREPHAPYPPGYQRHFEAPAVESMPMSVYASTASCSDVSACCEVESEVMMSDYESGDDGHFEEVTIPPLDSQQHTEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A087WRT4-1", "uniprot_id": "A0A087WRT4_MOUSE", "id": "A0A087WRT4-1", "name": "", "aln": "---------------------MGRHLTLLLLLLLFLQQFGDSDGSQRLEPTPP------IQFTHFQYNVTVHENSAAKTYVG--HPRKMGIYILDPSWEIRYKIVSGDSENLFKAEEYVLGDFCFLRIRTKGGNTAILNREVRDHYTLIVKAVEKATD-----AEARAKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTNGEFYYSFKDRTDVFAIHPTSGVVVLTGRLDFLETQLYELEILAADRGMKLYGSSGVSSLAKLTVHVEQANECAPIITAVTLSPSELDKD-PTYAIITVEDCDQGANGEIASLSIVAGDLLQQFKTVRSFPGSKAFKVKAVGAVDWDSHPYGYNLTLQAKDKGTPPQFSPVKVVHIISPQFRAGPVKFEMDVYRAEISEFAPPHTPVVLVKAIPSYS--HLRYVFKSAPGKPK--FGLNHNTGLISILEPIRRQHTSHFELEVTTSDKR-------ASARVVVKVLGTNSNPPEFTQTSYKASIDENAPIGAAVTRVSAMDPDEGENGYVTYSIANLNHVPFVIDHFTGTVSTSENLDYELMPRVYTLRIRASDWGLPYRREVEVLATITLNNLNDNTPLFERINCEGTIPRDLGVGEQITTVSAIDADELQLVRYQIEAGNELDLFGLNPSSGVLSLKHSLTDGLGAKVSFHSLRITATDGENFATPLYINLTVAASRK---------PVNLQCEETGVAKMLAEKLLQANKLHSQGDVEDIFFDS------YSVNTHTPQFGVTLPTGIEVKENLPVGANILFMNATDLDSGFNGKLVYAISGGNDDSCFTIDMETGVLKVLSPLDREVMDKYTLNITVYDLGIPQRAAWRLLDVTVLDANDNAPEFLQESYFVEVSEDKEVNSEIIQVEATDKDLGPSGHVTYAILTDTEKFSIDSMTGVVKIIQPLDREVQPVHYLKIEARDQATEEPRLFSTVLLKVSLDDVNDNPPRFIPPNYSVKVREDLPEGTIIMWLEAYDPDVGQSSQVRYSLLDHGEGH--FDVDKLSGAVRIVQQLDFEKKQLYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHTPVFSSFVEKGVVKEDVPTGSSVMTVSAHDED-TGRDGEIRYSIRDGSGIGVFRIDEETGVIETSDRLDRESTSHYWLTVYATDQGVVPLSSFIEVYIEVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSSNDKLTYRITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGVPPRSTIARVIVKILDENDNRPQFLQKFYKIRLPEREKADGDRSASKREPLYRVIAADKDEGPNAELSYSIEEGNEHGRFSIEPKTGVVSSKKFSAAGEYDILSIKAVDNGRPQKSSTTRLHIEWISKPKPSSEP--ISFEESVFSFTVMESD-PVAHMIGVISVEPPGMPLWFDIIG----------------------GNYDSHFDVDKGTGTIIVAKPLDAEQKSSYNLTVEATDGTTTILTQVLIKVIDTNDHRPQFSTSKYEVAVPEDTEPEVEILQISAVDRDEKNKLIYTLQSSIDPASLKKFRLDPATGALYTAEKLDHEAIHQHVLTVMVRDQDVPVKRNFARIVVNVSDKNDHAPWFTSPSYDGRVYESAAVGSVVLQVTALDKDKGRNAEVLYSIESGNIGNSFTIDPILGSIKTARELDRSHQVDYDLMVKATDKGDPPMSEMTSVRIAVTVADNASPKFTSKEYSAEISEAIRIGSFVGMVSAHSQSSVMYEIRDGNMGDAFNINPHSGSIITQRALDFETLPMYSLTVQGTNMAGLSTNTTVVVHVRDENDNPPVFTQAEYSGFISESASVNSVVLTDRNVP---LVIRATDADRESNALLVYQIVEPSVHNYFAIDPTTGAIRTVLSLDYEETHAFHFTVQVHDMGTPRLFAEYAANVTVHVIDINDCPPVFSKSLYEVSLLLPTYRGVNVITVNATDADSKAFSQVMYSITEGNIGEKFSMDHKTGTIAIQNTTQLRSR----YELTVRASDGRFTSMASVKINVKESRESPLKFTQDAYSAVVKENSTEARTLAVITAIGNPLNEPLFYRILNPDRRFKISHTSGVLSTTGIPFDREQQETFDVVVEVTKEHEP-----SAVAHVVVKVTVEDQNDNAPVFVNLPYYAVVKVDAEVGHVIRYVTAIDRDSGRNGDIHYYLKEHHDHFQIGPSGDISLKKQFEHDTLNKEYLVTVVAKDGGSPAFSAEVLVPITVMNKAMPVFEKAFYSAEIPENIQMHSPV-VHIQANSPEGLKVFYSITDGDPFSQFTINFNTGVVNVIAPLDFESHPAYKLSVRATDSLTGAHAEVFVDIIVEDINDNPPVFVQPSYSTTLSEASVIGTPVLQVRATDSDSEPNRGISYQLIGNHSK-SHDHFHIDSNTGLISLVRALDYEQSQQHRIFVRAVDGGMPALSSDVVVTVAVTDLNDNPPLFEQQVYEARISEHAAHGHFVMCVRACDADSSDLDKLEYSILSGNDHKSFIIDRETGIITLSNLRRHTLKPFYSLNVSVSDGVFRSSARVNVTVMGGNLHSPVFHQNEYEVELAENAPLHTLVVQVKASDRDSGIYSHVTYHIVNDFAKDRFYVNDR-GQIFTLEKLDRETPAEKVISIRLMAKDAGGKVAFCTVNVILTDDNDNAPQFRSTKYEVNIGSSAAKGTSVVKVFASDADEGSNADVTYAIEADS--ESVKENLEINKLTGLITTKESLIGLENEFFTFFVRAVDSGSPPRESVVPVYIKILPPEVQLPRFSEPFYTYTISEDTPIGTEIDLIRVEHGGAVLYILVKGNTPESNRDEFFVIDRQNGRLKLEKSLDHETTKWYQFSILARCTLDDYEVVASIDVSIQVKDANDNSPVLESSPYEAFIVENLPGGSRVIQIRASDLDSGANGQVMYSLDQSQD-ADIIESFAINMETGWITTLKELDHEERASYQIKVVASDHGEKVQLSSTAIVGVTVTDVNDSPPRFTAEIYKGTVSEDD-PPGGVIAILSTTDADTEEINRQVSYFITGGDALGQFAVENVQSDWRVYVKKPLDREQKDSYLLTVTATDGTFSSKARVEVKVLDANDNSPVCEKTSYSDTIPEDALPGKLVMQVSATDADIRSNAEITYTLFGSGAEKFKLNPDTGELRTLALLDREEQAVYNLLVKATDGG--GRSCQAAIVLTLEDVNDNAPEFTAEPYTITVFENTEPGTPLTRVQATDADTGLNRKISYSLVESADGQFSINERSGIIQLEKHLDRELQAVYTLTLKAVDQGLPRRLTATGTVVVSVLDINDNPPVFEYREYGASVSEDIVIGTEVLQVYAASRDIEANAEITYAIISGNEHGKFSIDSKTGAIFIIESLDYESSHEYYLTVEATDGGTPSLSDVATVNINVTDINDNSPVFSQDTYTTVVSEDAALEQPVITIMADDADGPSNSHIHYSIIEGNQGSPFTIDPVRGEVKVTKPLDRETISGYTLTVQAADNGNPPRVNTTTVNIDVSDVNDNAPLFSRDNYSVIIQENKPVGFSVLKLVVTDKDSSHNGPPFFFTIVSGNDENAFEVNQHGVLLTAATIKRKVKDHYLLHVKVADSGKPQLSSMTHIDIRVIEESIHPPAILPLEIFITAFGEEYSGGVIGKIHATDQDVYDTLMYSLDP------HMDGLFSVSSTGGKLIAHRKLDIGQYLLNVSVTDGKFTTVADITVHIQQVTQEMLNHTVAIRFANLTPEEFVGDYWRNFQRALRNILGVRKNDIQIVSLQ---------------PSEPHSHLDVLLFVERS-----GGTHVSTKQLLHKINSSVTDVEEIIGVRILEVFQKLCAG--LDCPWKFCDEKVSVDENVMSTHSTARLSFVTPRHHRTAVCLCKD----GTCPPVHHGCEDNPCPAGSECVADPREEKYSCVCPGGGFGKCPGSSS---------------ITFTGNSFVKYRLLENENRL----EMKLSMRLRTYSSHAVVMYARG-TDYSILEIHTGRLQYKFDCGSGPGIVSVQSIQVNDGQWHAVSLEVEGNYAKLVLDEVHTASGTAPGALKTLNLDNYVFFGGHLRQQGTKHGRGAQVASGFRGCMDSIYLNGQELPLNNKP-----RAYAHIEEWVDLSHGCLLTATEDCSSSPCQNGGVCNPSPTGGYYCKCSALYVGTFCEVSVNPCSSNPCLYGGTCMVDN-GGFVCQCRGLYTGQRCQLSPYCKDDPCKNGGTCFDSLDGAVCQCDSGFRGERCQSDIDECAGNPCRNGALCENTHGSYHCNCSQEYRGKHCED--ASPNHYVSTPWN----IGLAEGIGIIVFIAGIVLLVMVFVLCRKMISRKKKRQAEPEDKRLGPTTAFLQRPYFDSKLNKNIYSDIPPQVPVRPISYTPSIPSDSRNNLDRNSFEGSAIPEHPEFSTFNPESMHGHRKAVAVCSVAPNLPPPPPSNSPSDSDSIQKPSWDFDYDAKVVDLDPCLSKKPLEEKPSQPYSARESLSEVQSLSSFQSESCDDNESLAAPDLSKPRGYHWDTSDWMPS--VPLPDIQEFPNYEAIDEHTPLYSADPNAIDTDYYPGGYDIESDFPPPPEDFPAPDELPPLPPEFSDQFES--IHPPRDMPAAGSLGSSSRSRQRFNLNQYLPNFYPADMSEPQKQGAGENSPCREPYTPYPPGYQRNFEAPTIENMPMSVYASTASCSDVSACCEVESEVMMSDYESGDDGHFEEVTIPPLDSQQHTEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PBP8-1", "uniprot_id": "A0A8M9PBP8_DANRE", "id": "A0A8M9PBP8-1", "name": "", "aln": "------------MSSLKSPVTMGKSWTNHLLVLFMWICLG----AQQMEDALP------FQFTYPFYDVTIYENSAAKTYVE--CPIKMGIFMTNQSVDIWYTIESGDHDNLFKAETYVLGNFCFLRIRTKGGISASLNREIKDHYLLTINAIERHTG-----AEAQTQVKVQILDMNDLRPLFSPTTYSFFVPENSAARTSIGRVSATDADTGTNGEYYFSFKEWTDMFSIHPTSGVITLTGKLDYSEMALYEIDVLAVDRGLKLYGSSSSSSAAKLKVHVLQANEHSPVITAVPLTPWNTTSD-PTYAHVTVEDADEGQNGEIASLNIVAGDPLQQFKTFRTNPGSKEYKIKAVKKVEWEGYSFGYNLTLQAKDKGNPPKFSSAIVVRLGSPSEYTEIPRFEKSIYRVTLSEFAPPHSPVVMVKTVEKHS--KINYLLEFKMQQHDNPFIINPNTGLISTSGPIKAEKVSQYEFEVVTSDRR-------ASTKVVVSVSDMNNNAPVFQKSNYEASIAEHVPIGTSVLTVSATDMDDGENGYVTYSIVNVNKQPFVVDYFTGVISTTEDLDYETMPSKFSLRIRASDWGSPFRREAETIVSISLTNLNDNKPQFENIDCDVRVPRSLGVDEQIIRVSAIDADDLGVVQYRIDTGNNMNLFKLDSTSGVLALKKSLRDGDAVKQSFHRLQITAGDGEISSTPLFLNLTIVNAPK---------HVRSKCAETGALRTLAGLLLFGSKLDSQKETEDEFADI------HSVNRHAPRFIESTPAVIEVKENLPVGTSVALLRAADSDSGFNGKLLFVISGGDFDSCFTIESDTGWLKVFQPLDRETTDRYTLKITVYDLGLPQKSSSHLLDVKILDANDNSPEFLQREYIVDISEDTAIGTDIIQLEAKDKDLGVNGMVRYSFLTETDKFNIHEETGFVSVMRVLDREANPVFVLRVAAFDAAIDEPKLVSTVLLRINLEDVNDNPPMFVPQHYHIRVREDIPVGTLVLWLETHDPDLGLSGQVRYSLTDGDDGN--FQVDKMSGAVYVSQTLDFETRQIYNLTAKAKDRGRPNPLSSSCFIQVEIVAVNKNMYRPNFPFFVDWGTVLEDASVGTSVLKVAAHDED-SGRDGEVRYSIQGGSGLGVFTINEESGIITTQEILDRETKNHYWLTVYATDQGIVPLSSFVEVYIEVQDVNDNAPLTTEPVYFPSVSENSPKGVSVIQIQAFDLDSESSENLSYKISSGNPQGFFDIDFQTGLVTTTSRKLDREKQAEHLLEITVSDDGSPSKSTVVHVIVNVLDENDNSPQFLEKIFKIRLVER------LEAVEWEPIYRVIAYDRDESPFSDISYAIEEGEEQGKFFIEPTTGFVFSKEAFSAGEYNIITIKASDNGKPSKSSICRLHIEWIPKPKLAKQA--LAFEEIPLSFSVMEND-PVAHMVGVISAQPLDSPVWFTIKGDTHVKDAFHILQMSCDLNCTAGGSTDSRFDVEKASGTIIIAGALDAERQSNYNLTVEATDGTRSISTQVIVQVLDTNEHRPKFSQNQYEISIPEEIQPGMKILEINATDKDEDNKLSYTLLSSTDLFSLKKFRLDPGIGFLYTTEKLDHETMHRHILTVMVRDQGVPVKSNVVRVIINVEDSNDNPPWFTSSQYAARVFETAAIGSSVLQVTALDKDKSFNAEILYSIDSGNHGTSFIIDQSSGIITVARELDCETRDQYELIIKASDKGEPSLSAVTAVRITVTISDNTKPKFPSNSLSAEVSENVPVGSFVTLVSAFSQSTVFYQIIEGNEKGAFDINPNSGAVITRKKLDFETLSSYKLIVQGTDMAEMSSSVTVNIYLKDENDNAPVFTQSEYTGFISESAIIRSVVLNSQKAP---LVVRATDADQHSNARLVYQIMEPFACNYFSIDSRTGAIQTLSNLDYEQRRIFNFRVQVHDTGNPRLFAQDTANVTIHIININDCAPKFTQDSYEATLLLPTYKGVKVITVKATDEDSLPGNKLHFEIVDGNIGNKFWLDPTFGDIFVQNTTQLRSR----YRLTVQVSDGSFIGCANVKVNVKDNKSHNLKFTQDIFTAQVQENATEKKTLAVLSVVGNRVNEPLFYSILNPNSKFEIGRTSGVLFSTGIPFDREEQDLFEIIVEVIKEPGL-----NGPAHVLVKVQVEDVNDNAPFFVDQPYHAVVQVDQTVGSVFAKVTTVDRDIGKNAEITYYLKGHDKYFQVNPFGEISLKRPLELESIG-KYVINITAQDEGEPPLFSNAEVVISVVNKATPIFERPFYKIEILENVLVGTSI-LQVVANQSAGPRTVYSISGGNPFSQFDIHFNSGLIKVIQPLDYEAHPAYRLSIQATDSLTGANSDVFVDIILEDVNDNAPKFEAAVYSISISESTVIGTSVLQVVAMDPDAQSNAILFYKLHERDGS-TSDHFRIDAETGVIWTAGLLDHETQSQHDLIVKAVDGGAIQLSSEVQVTVYITDLNDNPPIFAQQLYNATISKISSPGQLVTCVKAFDADSHGSSNLEYAILSGNDNNIFAIDALSGEIVIANISRQSLKHFYSLILSVTDGVFCASAEANIYVMGENSHSPSFTQDEYLIELAENSPVGTLVGQVEAIDEDPGKYGQLTFFIMNDIARDKFNINED-GQIYTEESFDRENPEEKIIRISLMAKDGGGLLGFCNVIVILSDVNDNSPKFKHSEYKVTVPRDAPSSTTVIKTTAVDEDEGSNADIVYTIESD------IDHFEIHSLSGAIVTKESLIGLENGLYSFFVKAKDSGSPPKQSIIPVSIRIVPPETSIPKFAEPSLWLELSEDLAVGTEMDIFQAENELSVIYSLVGGNTPESNKHDVFAIDSTTGKLILTKRLDYETIKWYHLAVQVRDVKDDMEMISTVDVSVHLKDVNDNSPQFESFRYQSCIAENLPKGTSVVQVKATDLDSWLNGQITYALHENQQPPDVLQLFSVNSETGWITTLMEIDREKTDQYRITVVATDGAQGLQMTGTTVVEVTVVDTNDNPPLFTEAVFKGAVREDESTPGTVVTILSYVDSDSDEVNRRFNCFITGGDPQGLFDVKHTDGVWVVAVSKTLDREERDFYLLNITATDGTFVAKAAVEITVLDANDNSPVCEKDVYAQAVPEDVLIGKHILQVSATDADIQSNAEITYQLSGSGAESFTIDSKTGAVKTLATLDREVTDVYNLTVRAVDKD--NHFCQASLLITVEDANDNAPKFTSDPHHVSIYQNTQPGTYVARLEAFDADIGMNGKIRYSFEDSAGGLFSIEESSGIISLERSLDKQMKAMHVLRVRATDQGFPHRLSSLGSVLVTVLDANDHPPVFERREYISTVPEDVTIGTKLLKVFASSKDRQMTSQTTYSFSSGNEQGAFRIDSQTGDIFVMEPLDYEESSQHYLTVKATVGGKQSLSDMATVSIHLQDINDNSPVFSQKIYSAVVSEDTRLASTVLTVLANDLDGPLNNQIRYSIEESNQSCPFIMDAVSGELQLARQLDREMVASYMLTVMASDSGSPLKSDSAAINIAVSDVNDNPPVFSQANYSLIIQENLPSGTSVLQLNVTDNDSLHNGPPFSFILIG-VEANPFSIDQQGLVKTAGPLT---KGQYTLQVQVSDNGKPPQKSVTSITVLVAQASMFPPSVFPLEIFIILLEDEYSGGTLGKIHATDQDEHDKLAFSLDP------QSHSLFSIIGTDGRLLAREGLDVGHYQLNVSVSDGHFSVSSIVKVNVLQVTEQMLDSSISIRFAGITTEDFIQDHWKNFQKMLRSVAGARRGAINLISLQ---------------SAGFGDGLDVLLYFERP-----RRGAGALEALSQKISSSRGAIKEMTGLHVVRVLNSRCLS--SECPDGKCRRVLLFNQTTMGAYSTARVSYITPRHHMTAKCLCTD----SKCLKQEYTCVNSTCPEGYECVSGFGQDKHSCICTGAAKVKCSGGSS---------------MTFSESSYIKYSLMESMK------GLKLTLKLKTLSTEGTIMLARG-TGHSILEIAGGRLQFQFDCGWGFATVSVHSVLVNDGQWHMAELEVKGNYARLVLDQLHSASGIAPGPLHCLNLGEQVVLGGHAQHLGSRRRRNLPASNSLQGCMDSVLLNGHRLSLDSGG-----PLGVTIEDMVGVSPGCFGFTSPVCSSNPCLNGGSCLMRQSGGNICKCSPSFSGTRCEVKISPCDSNPCLYGGTCIQNN-LDYSCKCRGKYSGQRCQIGPYCKENPCQNGGQCIDSLDGAICECEPGFKGERCMIDVDECVDRPCFNDGHCVNTRGSFTCSCMIGFSGRLCEIGTEVSNQPISSSWN----SWIGELVAILAFLAVIFVVTLLFLIVWKGSCKRIKRDKDLD--KVKDIDSYIQRLSFYNHGKNKSRSDTPPLVPVRPISYTPSIPGECRNNRG----------SVPEFSNFTADPLFGLRKSVAVCSVAPNLPHRKASYSHSENDSIQQMDWDEEYDEKILDLTSCLAMEDDYISLSRDNRG------LQSTCSLQSDVMDDN------------SYYWDTSDWQQN--IYSPGIQGFLQYEFVQMTSPIHTS-PETVHMDFTTVGEDIETFLP---------------------------------------------------LTTLLPNSDQLTR---------------------PEGHHAIHPTVRSNFMTSSQHPSPDSPESVQTTAEMLQDQHIRSSE----------TVDFLESPV----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VW71-1", "uniprot_id": "FAT2_DROME", "id": "Q9VW71-1", "name": "Fat-like cadherin-related tumor suppressor homolog", "aln": "MFTMKIKKYVTPVKRKAFTILQWISLLCSLWLIPTVQSKADEKHTATLEYRLENQLQDLYRFSHSVYNVTIPENSLGKTYAKGVLHERLAGLRVGLNAEVKYRIISGDKEKLFKAEEKLVGDFAFLAIRTRTN-NVVLNREKTEEYVIRVKAHVHLHDRNVSSYETEANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADLGINGEIYYSLLMDSEYFAIHPTTGEITLLQQLQYAENSHFELTVVAYDRGSWVNHQNHQASKTKVSISVKQVNFYAPEIFTKTFSSVTPTSNPLIYGIVRVNDKDTGINGNIGRLEIVDGNPDGTFLLKAAET-KDEYYIELNQFAHLNQQHFIYNLTLLAEDLGTPRRFAYKSVPIQIKPE-SKNIPIFTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGDEFRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAVPFEIDHFSGIVKTTSLLDFETMKRNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFERVNCYGKVTKSAPMGTEVFVTSAIDFDAGDIISYRLSDGNEDGCFNLDPTSGSLSISCDLKK---TTLTNRILKVSATDGTHFSDDLIINVHLMPEDLGGDSSILHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFVN-FPQELSINESVQLGETVAWIEAKDRDLGYNGKLVFAISDGDYDSVFRIDPDRGELQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYALSVECSDFTVNATTGCLRLNKPLDREKQDNYALHITAKDGG--SPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDP-SLTSDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVNDQ-GSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIKTTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPSS--------ATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIAKPLDSDNEFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTENDKPGFLVTQILAVDDDNDQLWYNISN----------------------GNDDNTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDGTFTAFTNLLVQVIDINDNPPQFAKDVYHVNISENIEEESVIMQLHATDRDEDKKLFYHLHATQDPSSLALFRIDSISGNVIVTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSVFEIDPTFGIITLAGNLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVTQVTARSSSSIFFNIISGNINESFRINPSTGVIVINGNIDYESIKVFNLTVKGTNMAAESSCQNIIIHILDANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVDDLAKNFFKIDSTTGAIELLRQLDYETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFENVFVRQVSAKDADN---DTLRFDIVDGNTNECFQIEKYTGIITTRNFEILNNENDRDYALHVRASDGIFSAILIVKIKVLSAIDSNFAFQRESYRFSAFENNTKVATIGLVNVIGNTLDENVEYRILNPTQLFDIGISSGALKTTGVIFDREVKDLYRLFVEAKSMLYDGMNSNVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLDSAENGEVRYELKKGNGELFKLDRKSGELSIKQHVEGHNRNYELTVAAYDGAITPCSSEAPLQVKVIDRSMPVFEKQFYTVSVKEDVEMYSALSVSIEAESPLGRSLIYTISSES--QSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGVYAEVVLSVSIMDVNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLYLKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDGVHTAYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIVSEEMKKIFLIDQTTGVITSKVTFDREKKDE--YVVLLKVSDGGGKFGFASLKVIVVDVNDNVPYFLLKEYKMVVSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQKSNDKAVKDVIEINEKTGDIVFKSKAESYGVNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLHMIGNYTFKFSIAA--------DQDHFMISDSGELILQQTLDREQQESHNLIVVAETSTVP-VFFAYADVLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYLESDTE--NIQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAADN-GHPKHDAKVPVTIKIVDYNDNAPVFKLPIEGLSVFENA-LPGTVLINLLLIDPDIE--KQEMDFFIVSGDKQAQFQIGKSG---ELFIAKPLDREQLMFYNLSIIATDGKFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFDFQS--KLRFYLSGKGADDFSIGKESGILKVASALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGENHDYFKISKSTGIIRLHKSLDRETISLFNLTVKAEDCGVP-KLHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTFLQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERGDNIGQFSIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFSSSNYSVVLQENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRLEQDGSLRTASRFNHNLQDEFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPIVTPLEVTINSFEDDFSGAFIGKVHASDQDKYDELNFSLVSGPDDMYQSSKLFNISNNTGKIYAISNLDIGLYKLNVSVSDGKFHVFSIVKINVELVTNDMLKESVVIRFRRISASEFLLSHRKTFMRSIRNIMRCRQKDVILITLQSDYQKASQHAVGNRRARSIDSDLNVVFAVRKQQIIPDSDEFFTSDEIRQTLIDKKNEIENETNLVVEDVLPSTCQSNKNDCVHGECKQILQILKNNVTTTFTDVISFAAPSYIPVNTCVCRPGFDGKHCKETVNACSTDPCSPQRICMPSGSALGYQCVCPKGFSGTYCERKSSKCSNESCDMGLFTAVSFGGKSYAHYKINKVKAKFTLENGFSYSLQIRTVQQTGTLLYASGKVDYNILEIINGAVQYRFDLGSGEGVISVSSINISDGEWHQISLERSLNSAKVMVDNKHVSHGSAPGVNGILNIQSNDIFVGAEVRPHPSIIGYEDIQRGFIGCMANIKIAKESLPLYISGGSTIAALKRFTNVEFKCDPSNVLVRLGICGSQPCANSGICKELDTDVFECACQPRYSGKHCEIDLDPCSSGPCLFGGRCDYHGPNNYSCTCPIHLSGKRCEYGKFCTPNPCKNGGICEEGDGISHCMCR-GYTGPTCEIDVDECENQPCGNGATCINEPGSFRCICPSYLTGASCGD--PLYSNSISTKLKNFSIEHISGIISGVAVVLVIISCVLCCVVLKRSSSSKRRNRLEKDKNKSSYKEANLNSLVDKDNYCKPNVKLSNLEVNQRPISYT-AVPNDNLVLSNRNFVNNLDILRSYGSAGDELENVPFEYQKVNRNKQHVNIN----SCHSTDADNAYKQEWCEQMHLRTFSENKLNNELKRDFGPSVSRFSTGKLIQVEMPNVCHSSSANFVDYSALANG----QYHWDCSDWVRKSHNPLPDITEVPGAEIADSSSLHSNDSNESKSKKAFFVHREDGDVDPTRDIAALNEDIGSEYLDSEAESCLEPFMLPRSSNQPLSRLSSFNNIENEDYKSNTVPLPSKVSHSCKVYLRHPDSYLPTMHFPSETDGESSMTEGPISRMEIKTRRTISENSEEAYLFPCTVGEIGSNSNISVRLCEIEDSELEEFLPQQQTNN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: . : :* :*:: *:**: *** .***. ::. :: * * *** ::***** ::*:*.** ***: . .. **** :.* : ::* : . *:.:::::::** *** *** ** *:. :**::. ** :*:* *** * *** *:*: :: *:****:* :.* :*:: * :*: ::* *** : .. :* :*:.: : *.* :* * : .::. : *. : *:* * * **:*. *.** *: * : . .. : :: . : : ***** *:* *.* :*: * .*. * .:*.. :.* ** : **: :*. : :: : * :* ::*:: : :: : : : * : *: :*::* :.* . *.* * * : :: *: *: * ::* * *.***.*::***.*:* ** :*:*:* :.*:. **:* * : * ******* *:**:.* :* :.::*** * **.::* :.:. :. :: .**** * :: *::. **: . * *:..** *::. .* . .. : : *:::* ** : * :*: : :* ***. : ** * ..* . : . * * :. * * *.* * :.::*. :* .: :.: * * *:****::.:*.*: ** * *: : * *::: **** :.*.*:******* * ::: ::* : ::*.*** * : : . ::*. : : : :.*.* * * .. * *:: .: . *.:. ** : : : **** : . *:: * * . .* * * .:: : ::*****.* * .* .:****:* **:: :*: * *:* ..::::** : :.. * :** :**: **:*.:*::** . * * * * .*:* : : :: **:* . * * ** * * *: . *: *:.*:*:* * :.:: *** .*.*:*:* :.:: * * : . ** *:...****: * * .:****. :*:**:*:: *** * * :***: .: * * :.*.:: ::*** * ...:.: *.* *** *:*.*. :**::.**.******:* **:**::::*:* * *: :::*.:** *** *:* ::.:*::: . * :.:::* * * *.. . ::*:*:.*: :.:* *:. * : . :.: : *** *** *.**. *::* :. : :. : : . : *.* * : :::.: . :*: * . *. *. * : : .*.*::: ** * :..****:..**** : *:::::*:* *:: *:*: . *.: :.*: *::: *.*:**.:** * * :: * ** **:*. * : .:::**.* :* * *:*:**..* * * .::::** * **: * **: .:* *:**:** : :* *:*:*.. ***: *** :** *. * ** * *. * :*: . :* * :** * *.*.:* .*:* **:::* ***.::. : *: * : :*:** *:* *.*::.::* .** :* *** :* :: . :*:*:: :.* ::**:** *: .: ::: * *** * * * ** * :.*** : * **. :. . *.::. *** *. : *:*:: . .:* **. ****. : .**** : * * * * *.*:*.: :*:**:::*::***.* * : :.:*:***:..* * *.*.* *. . : :.*.:** .: * :: * : :* *... * * *:.*** * . **::* . . : * :: : . ** *: *:.::..:** ::* : * **** *.*. :**.* :** **** :: : :.**. . * . :.: * * ***.*.**: **:*.*.:* * :: *.::* * ..*.:: * ** . : . .*. . : . :* :.:.* * . .. ::. : :.*:::: *:**: **. .: *.: : :.: : : *:.. * .*:*:. . ..* *.:*:* : *: **:* .:: :*::*****:*. ::*.:.: : *:** * : * ::.* : :** :::: * * *: .* : * : ... . : * :* * : **:* * :.*.. * * *** * : :.*****.* * : * : :* : *::* :* * * . ..*:* *: **: : : ** :* * : *: . : * * :**:***. : :. :: :: * :** * *. * ::.** : *:: * * * *.:: : *:.: :. * ::: * * : .:***. * : * ..*.** ..*..: **: * *** * * .:*:: : . . :::.. * * * .*..: : * . : :**:. :* *. *.. . : ***:* * *.* .* : * :.*: .: .:* * :. : *. . ** : :: :. : :. .: . : .*.* * : ** * : ::: : .. ..: ** :.::* *** * ::. *.: :.** :::: *:* *: **:: * *... . :: : * :: :**** * .:*:* .*.:.*:*:* : ... * :.:.* **..* *. : :* *: * *: * *.* : ::.. **..** . * : : : *.****: * *.: ****.* :** **: * * ***:* * * * : *. *. ::::.* * *::* :: : * *.**:.*.:. .:* ::. : **** *:* .:. * : * : :::*::* *** * *: : ::: :::: .* ::::.* * * *:* :* **: . . *.*.: :*** *.: **:: ::. * ::* * *.* :* : .:* *.:** **:** *. *:* ..: *: **:: :*:*:* * .:: * : ****:* * :** ** :.: **** * ::**::* **. .**: * *.: : *****:*.* *. * :.** : . :: : * * *. *. : *.* .:: * :*. * :.::: **** :: * * : *.*.*.* : ::..:** : *.***.*:** ***:::*** * .* : ::* *. * .*: * : : * :: .* : *:. :. :..: ::*:* *.*.* * : : : : : * .** : ***: * :::**. :**:**:*** :* * :** . : **.: .. *:: * **:* * *****:**:* . : :.::: **::**. :: *** ::..:*: .: :.* : :*.: *: : :::** . *:*:: ..: : . : :.: .. ::: .: : *: . * . :* * . : . :. : : * :*: :* : . *:* * * ..*. *:.. : *:*. . .* ::: .*: :* : : :. :::::* . ..:: * * ..:.**** * :*::** * * . :** *: :.**:** ** . * *::::*: * : * *** **: . .: * : . .: *** .: : . *.* : . . . . *.*.** *.* * :. * *.. : *. **:.:.**.* ***:** * .. .: * * :*:**: . :*. :**:*** * :. . : * * *: * * *:*** ..** :.. * * **: * * * * .: :*: : :. :. :..: *. .: :: : . : :. : . : : :: .: : . * ****** ::*.: . : : : : * . *: * :: *. : .* : . : .. * . :: :*. : *:** *** . *.* . * : : . :: . : * . :* . * . : . . . ... : . : : . ", "identical_positions": 1243, "similar_positions": 1478, "identity": "26.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-565", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P1F6-1", "uniprot_id": "2ABA_MOUSE", "id": "Q6P1F6-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "aln": "MAGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKVN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P63151-1", "uniprot_id": "2ABA_HUMAN", "id": "P63151-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "aln": "MAGAGGGNDIQWCFSQVKGAVDDDVAEADIISTVEFNHSGELLATGDKGGRVVIFQQEQENKIQSHSRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAQFLLSTNDKTIKLWKISERDKRPEGYNLKEEDGRYRDPTTVTTLRVPVFRPMDLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPANMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSFFSEIISSISDVKFSHSGRYMMTRDYLSVKIWDLNMENRPVETYQVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKILHTAWHPKENIIAVATTNNLYIFQDKVN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WDS4-1", "uniprot_id": "X1WDS4_DANRE", "id": "X1WDS4-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B", "aln": "MDGHGDGQ-SRWCLSQVKGAVDDDVAEADIISAVEFNHSGELLATGDRGGRIVIFQQEQENKSLPQCRAEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPQKNAAHFLLSTNDKTIKLWKISERDKRPEGYNLKEEDGRYRHPSSLTTLRVPVFQPMDLMVEASPRRVYANAHTYHINSISVNSDNETYLSADDLRVNLWHLDYTDRSFNIVDIKPANMEELTEVITASEFHPLQCNTFVYGSSKGSVRLCDMRASALCDQHSKLFEEPEDPSTRSFFSEIISSISDVKFSHSGRYMMTRDYLTLKIWDLHMESHPVETYQVHGYLRSKLCSLYENDCIFDKFECCWRGDDSEVMTGSYNNFFRMFEREGQRDVTLEASWENGSPGCPLKSWRVSTGSRRKRNEIGVDCLDFSRKILYTSWHPQENIVALATVNNLYLFQEKLN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * *.*: :**:******************:**************:***:********** .:.*.***************************************:***********************************.*:::********:************::************:*** **********:*****: ************************:**** .******.****::************:************.*****************************::*****:**.:******** ***********************.*.** *************:*: :**:***** **..* **. :*.:..:**::**.**.***.:***:*:***:***:*:**.****:**:*:*", "identical_positions": 366, "similar_positions": 64, "identity": "81.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-566", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63279-1", "uniprot_id": "K1C19_RAT", "id": "Q63279-1", "name": "Keratin, type I cytoskeletal 19", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSYSYRQS--------------SAMSSYGGMGGGP----VRFGSGGVFRAPSIHGGSGGRGVSVSSTRIVSSSSGGYVGGRGGSFS---GALTVTDGLLGG-------NEKITMQNLNDRLASYLDKVRALEQANGELEVKIRDWYQKQGPGPFRDYSQYFKTIEDLRDKILGATIENSKIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQIENLKEELAYLKKNHEEEISALRSQVG-GQVSVEVDSTPGIDLAKILSEMRSQYEAMAEKNRKDAEAWYLTQIDELNTQVAVHTTQIQINKTEVTELRRKVQDLEIELQSQLSMKAALEGTVAEIEARYGAQLSHIQGVISSIEVQLSNVRADTERQNQEYQQLMDIKSRLEQEIATYRSLLEGQEAHYNSLSIAKAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19001-1", "uniprot_id": "K1C19_MOUSE", "id": "P19001-1", "name": "Keratin, type I cytoskeletal 19", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSYSYRQT--------------SAMSSFGGTGGGS----VRIGSGGVFRAPSIHGGSGGRGVSVSSTRFVTSSSGSYGGVRGGSFS---GTLAVSDGLLSG-------NEKITMQNLNDRLASYLDKVRALEQANGELEVKIRDWYQKQGPGPSRDYNHYFKTIEDLRDKILGATIDNSKIVLQIDNARLAADDFRTKFETEHALRLSVEADINGLRRVLDELTLARTDLEMQIESLKEELAYLKKNHEEEITALRSQVG-GQVSVEVDSTPGVDLAKILSEMRSQYEIMAEKNRKDAEATYLARIEELNTQVAVHSEQIQISKTEVTDLRRTLQGLEIELQSQLSMKAALEGTLAETEARYGVQLSQIQSVISGFEAQLSDVRADIERQNQEYKQLMDIKSRLEQEIATYRSLLEGQEAHYNNLPTPKAI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08727-1", "uniprot_id": "K1C19_HUMAN", "id": "P08727-1", "name": "Keratin, type I cytoskeletal 19", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSYSYRQS--------------SATSSFGGLGGGS----VRFGPGVAFRAPSIHGGSGGRGVSVSSARFVSSSSS---GAYGGGYG---GVLTASDGLLAG-------NEKLTMQNLNDRLASYLDKVRALEAANGELEVKIRDWYQKQGPGPSRDYSHYYTTIQDLRDKILGATIENSRIVLQIDNARLAADDFRTKFETEQALRMSVEADINGLRRVLDELTLARTDLEMQIEGLKEELAYLKKNHEEEISTLRGQVG-GQVSVEVDSAPGTDLAKILSDMRSQYEVMAEQNRKDAEAWFTSRTEELNREVAGHTEQLQMSRSEVTDLRRTLQGLEIELQSQLSMKAALEDTLAETEARFGAQLAHIQALISGIEAQLGDVRADSERQNQEYQRLMDIKSRLEQEIATYRSLLEGQEDHYNNLSASKVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q3N5-1", "uniprot_id": "A0A8M9Q3N5_DANRE", "id": "A0A8M9Q3N5-1", "name": "", "aln": "MACSKTYPETCWKTCSESSPETYSTSCSETSEICPKPCSFTFPETCRKTCSETSSDSCLKTCPETCSTQSYPETCYESCPKHCYSTCPEICPKPSSFTCPKTCLKTFSESSSITCPETCSNTCTAPCSFTCPETCLKTCSETCPKPCSFTCPETCLKTCSETCSKPSSFTCPETCIKTSSDICSKPCSFTCPETCPKSFSITCPQTCSETCLKTCSDTCPKPCSFTCPDTYLKTCSETCSETCPKPCSFTCPESCLKTYSETCSDTLSKSCSFNNPKPCPDNCLKTCSETCSTTCSETCSKPCSFTFPDTCPKTCPEPCTSSCPETSSETCPKPCPISNPKSCFSTFSNSCSVSSVTVPRHCRTVTTKAHSVYGCGVGGRTRISSCSYRPNTCSPCPLYKLDGFGERFGARIMAGGCYGRDYDYHQLNEKATMQNLNDRLASYLDKVHFLEAANATLEKQICDYFEKKDPICQKDYSCYLKTIDCLQKKIKDATITNGKILLRIDNSKLAADDFRIKYENELSIHQCVKADIDNLRCILDKTCLAKADLELQICTLEEELVYLRKTHQEDVAALMCQLTNSKVCVEVDAAPQQDLKKVLDDIRCYYDTIIDKHCTEQECWFKEKMAGLCKDTAINTECLETSMSRISDLRRTLQSLEIELQSQISLKGALECSLLETEARYSTMLAGYQKHINAYEAELCQVRAGIEQQGRDYDALLDIKSRLEQEIATYRCLLENQASQC---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** . . : *. *::.. . . * . :* *::* . * . :** ..:.. ..:. *. :.* . *** ****************: ** **. ** :* *:::*:.* :**. * .**: *:.** .*** *.:*:*:***::******* *:*.* ::: .*:***:.** :**: **::***:** *:***.**:*.*:*::::* *: .:*.****::* ** *:*.::*. *: : ::: .: *. : : * :.* :: :: . :.:::***.:*.********:*:*.*** :: * ***:.. *: * *.. *.:* :***. *:*.::*. *:**************.***.* : ", "identical_positions": 161, "similar_positions": 134, "identity": "21.47%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-569", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96QS6-1", "uniprot_id": "PSKH2_HUMAN", "id": "Q96QS6-1", "name": "Serine/threonine-protein kinase H2", "aln": "------------------------------MGCGASRKVVPGPP---------------------------------------ALAWAKHEGQNQAGVG------------GAGPGPEAAAQAAQRIQV-------------------ARFRAKFDPRVLARYDIKALIGTGSFSRVVRVEQKTT---------KKPFAIKVMETRERE-------------------GREACVSELSVLRRVSH--RYIVQLMEIFETEDQVYMVMELATGGELFDRLIAQGSFTERDAVRILQMVADGIRYLHALQITHRNLKPENLLYY----------------HPGEESKILITDFGLAYSGK-------------KSGDWTMKTLCGTPEYIAPEVLLRKPYTSAVDMWALGVITYALLSGFLPFDDESQTRLYRKILKGKYNYTGEPWPSISHLAKDFIDKLLILEAGHRMSAGQALDHPWVITMAAG-----SSMKNLQRAISRN-------LMQRAS-PHSQSPGSAQ------SSKSHYSHKSRHMWS----------------------------------------KRNLRIVESPLSALL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B4V4-1", "uniprot_id": "A0A8M3B4V4_DANRE", "id": "A0A8M3B4V4-1", "name": "non-specific serine/threonine protein kinase", "aln": "--------------------MLLKPHKVFIMGS-SSGKVLPESSSSKRGYF---------------------------CLFNSIVIFNKQESEGEKCVEKQQTGLWKKRRDGGASGEELHLEENIENRS-------------------AKFRAKFDPRVTARYEIQALIGHGSFSRVVRAEHKQT---------HQPFAIKLLDLRAPE-------------------GLESCQAELRVLRRVNH--PNIIRLTEVFLTPHRVYLVLELATGGELLERVLSRGTFRERDATKALLMVTSGLAYLHNLGVIHRDLKPENLLYY----------------HPGQDSRLIITDFGLACWDKSIQRDDLELTVGLEEKGWALRTLCGTPEYLAPEMLARRGCGRAVDMWALGIITYVLLSGSLPFDHSSRAKLFRAILKGSYSFHGEPWRSVSSLGKGFINGLLTVVPEQRMSAEEALHHPWLVNMAAC-----SSNKNLQRSISRN-------LQRRASRTSSRCPSSAS------GSQASRSSSSRLGLR----------------------------------------NGSRCQNISTVSEGLVC------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38623-1", "uniprot_id": "RCK2_YEAST", "id": "P38623-1", "name": "Serine/threonine-protein kinase RCK2", "aln": "MLKIKALFSKKKPDQADLSQESKKPFKGKTRSSGTNNKDVSQITSSPKKSFQDKNIVQYPSVVADDHHMKSLTDELVTTIDSDSSPSDNITTENVETVTSVPAIDVHESSEGQLSSDPLISDESLSEQSEIISDIQDDSTDDDNMEDEIPEKSFLEQKELIGYKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKADLSSINGDHRKKDKGKDSTKTSSRDQVLKEVALHKTVSAGCSQIVAFIDFQETDSYYYIIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIG-IVKLADFGLSKQIFSKNTKTPCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKISRGEYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDDPWLNTFDCLPKEGESSQKKAGTSERRHPHKKQFQLFQRDSSLLFSPAAVAMRDAFDIGNAVKRTEEDRMGTRGGLGSLAEDEELEDSYSGAQGDEQLEQNMFQLTLDTSTILQRRKKVQENDVGPTIPISATIRE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :. * :. . : :. * * .. : : :: :: : *.: ** *:**:*.*. . :..***::. . . : *: : : *. *: : :. * *:: ** ****:: .:: * * : : : :: .: ::* * : **::******: .* .: * *:. . : . :* *** * ***:: . ****.:* : *.:*.* ** ... * . * :*.*.: * .:* .*. : ** : . :* . : *..**: .: . ** *: : *: * :* * .. * .. : ..* : . :. : ", "identical_positions": 80, "similar_positions": 121, "identity": "13.09%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-570", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L6W2-1", "uniprot_id": "A0ABK0L6W2_RAT", "id": "A0ABK0L6W2-1", "name": "Serine/threonine-protein kinase Nek10", "aln": "MPDQDTKVKSIEKATDKKQQGTTTRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQSNMSKSDPTIKTGGHRARGQWHESTEAVELENFSINYKNERNFSKHPQHQLFQEIFTALVRNRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHKLGGIEDLAQYMEIVANEYLGYAEEQHCVDKLVNMTYIFQKLAAVKDQREWVTSSGAHKTLVNLLGARDTNVLLGTLLALASLAESPECREKISELNVVENLLMILHEYDLLSKRLTAELLRLLCAEPPVKEQVKLYEGIPILLSLLHSDHLKLLWSVVWILVQVCEDPETSVEIRIWGGIKQLLHILQGILCGNISEHLKRLQRDEQHASLVISATGKTKEKDRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPGEIQENTVSLQAACCAALTELALNDTNAHQVVQENGVYTIAKLILPNKQSNAAKTNLLQCYAFRTLRFLFSMERNRPLFKRLFPTDLFETFIDIGHYVRDIGAYADLVSQLNLLLEDELKQIAENIESINQKKAPLKYIGDYALLDHLGSGAFGCVYKVRKRSGQNLLAMKEVNLHNPAFGKDKKDRDSSVKNIVSELTIIKEQLYHPNVVRYYKTFLENDRLYIVMELIEGAPLGEHFSSLKEKQQHFSEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNIMLGDKDKVTVTDFGLAKQKQESSKLTSVVGTILYSCPEVLKSEPYGEKADVWAAGCILYQMATLNPPFCSTNMLSLATKIVEAVYEPVPEGIYSEKVTETIRRCLTPDAEARPDIVEVSSMISDIMMKYLDSLSTSQLALERKLERERRRTQRYFMEANRNAVM--CHHELSLLSQETFEKASLSSSSSGAASLKSELSESAELPGEGCHIPCGKEEDRGCEEELSEDNFQLESVEKDLYSELDEELDVSDNCSSSSSSPLKESTFSILKRSFSASGRERHSQARDFIGGLGSRPRP---------------------------------------------------------ASAGIAVSQRKVRQICDPIQQILIQLHKVIYITQLPPALHHDLKRRVIERFKKSLFSQQSNPCNLKSEIRKLSQGSPEPIEPNFLTSDYHLLRHSSTAKNWSPSDPTGPSSGLEVEEGITYEQMQTVIEEVLEESGYYNFTTNRSSRCHSYPWGTKSYTAKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UGM2-1", "uniprot_id": "NEK10_MOUSE", "id": "Q3UGM2-1", "name": "Serine/threonine-protein kinase Nek10", "aln": "MPDQDTKAKSTEKTADK-QQGTTTRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNNMTKSEPTIRTGGHRARGQWHESTEAVELENFSINYKNERNFSKHPQHQLFQEIFTALVRNRLICREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHKLGGIEDLAQYMEIVANEYLGYAEEQHCVDKLVNMTYIFQKLAAVKDQREWVTASGAHKTLVSLLGARDTTVLLGALLALASLAESSECREKISELNVVENLLMILHEYDLLSKRLTAELLRLLCAEPQIKEQVKLYEGIPILLSLLHSDHLKLLWSVIWILVQVCEDPETSVEIRIWGGIKQLLHILQG---------------------------------DRNFVSDRSSIGSLSSANAAGRIQQLHLSEDLSPGEIEENTVSLQAACCAALTELALNDTNAHQVVQENGVYTIAKLILPNKQSNAAQTNLLQCYAFRTLRFLFSMERNRPLFKRLFPTDLFETFIDIGHYVRDIGAYKDLVSQLNLLLEDELKQIAENIESINQKKAPLKYIGDYAVLDHLGSGAFGCVYKVRKRSGQNLLAMKEVNLHNPAFGKDKKDRDSSVKNIVSELTIIKEQLYHPNVVRYYKTFLENDRLYIVMELIEGAPLGEHFNSLKEKHHHFSEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNIMLGDKDKVTVTDFGLAKQKQESSKLTSMVGTILYSCPEVLKSEPYGEKADVWAAGCILYQMATLSPPFCSTNMLSLATKIVEAVYEPVPEGIYSEKVTDTIRRCLTPDAEARPDIVEVSSMISDVMMKYLDRLSTSQLALERKLERERRRTQRYFMEANRNAVT--CHHELALLSQETFEKASLSSSSSGAASLKSELSESAELPGEGCHIPCGKEEDRVCEEVLSEDNFQLESVEKDLYSELDDELDVSDNCSSSSSSPLKESTFSILKRSFSASGRERHSQARDFIAGLGSRPRPGPQMSTFVVES----------------------------------------------ASAGIAVSQRKVRQICDPIQQILIQLHKVIYITQLPPALHHDLKRRVIERFKKSLFSQQSNPCNLKSEIKKLSQGSPEPIELNFLTSDYHSLRHSRAANNWSPSDPTGSPSSFEVEEGVTYEQMQTVIEEVLEESGYYNFTTKR------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZWH5-1", "uniprot_id": "NEK10_HUMAN", "id": "Q6ZWH5-1", "name": "Serine/threonine-protein kinase Nek10", "aln": "MPDQDKKVKTTEKSTDK-QQEITIRDYSDLKRLRCLLNVQSSKQQLPAINFDSAQNSMTKSEPAIRAGGHRARGQWHESTEAVELENFSINYKNERNFSKHPQRKLFQEIFTALVKNRLISREWVNRAPSIHFLRVLICLRLLMRDPCYQEILHSLGGIENLAQYMEIVANEYLGYGEEQHTVDKLVNMTYIFQKLAAVKDQREWVTTSGAHKTLVNLLGARDTNVLLGSLLALASLAESQECREKISELNIVENLLMILHEYDLLSKRLTAELLRLLCAEPQVKEQVKLYEGIPVLLSLLHSDHLKLLWSIVWILVQVCEDPETSVEIRIWGGIKQLLHILQG---------------------------------DRNFVSDHSSIGSLSSANAAGRIQQLHLSEDLSPREIQENTFSLQAACCAALTELVLNDTNAHQVVQENGVYTIAKLILPNKQKNAAKSNLLQCYAFRALRFLFSMERNRPLFKRLFPTDLFEIFIDIGHYVRDISAYEELVSKLNLLVEDELKQIAENIESINQNKAPLKYIGNYAILDHLGSGAFGCVYKVRKHSGQNLLAMKEVNLHNPAFGKDKKDRDSSVRNIVSELTIIKEQLYHPNIVRYYKTFLENDRLYIVMELIEGAPLGEHFSSLKEKHHHFTEERLWKIFIQLCLALRYLHKEKRIVHRDLTPNNIMLGDKDKVTVTDFGLAKQKQENSKLTSVVGTILYSCPEVLKSEPYGEKADVWAVGCILYQMATLSPPFYSTNMLSLATKIVEAVYEPVPEGIYSEKVTDTISRCLTPDAEARPDIVEVSSMISDVMMKYLDNLSTSQLSLEKKLERERRRTQRYFMEANRNTVT--CHHELAVLSHETFEKASLSSSSSGAASLKSELSESADLPPEGFQASYGKDEDRACDEILSDDNFNLENAEKDTYSEVDDELDISDNSSSSSSSPLKESTFNILKRSFSASGGERQSQTRDFTGGTGSRPRPALLPLDLLLKVPPHMLRAHIKEIEAELVTGWQSHSLPAVILRNLKDHGPQMGTFLWQASAGIAVSQRKVRQISDPIQQILIQLHKIIYITQLPPALHHNLKRRVIERFKKSLFSQQSNPCNLKSEIKKLSQGSPEPIEPNFFTADYHLLHRSSGGNSLSPNDPTGLPTSIELEEGITYEQMQTVIEEVLEESGYYNFTSNR---YHSYPWGTKNHPTKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AJH8-1", "uniprot_id": "A0A8M3AJH8_DANRE", "id": "A0A8M3AJH8-1", "name": "Serine/threonine-protein kinase Nek10", "aln": "MPLQDRKSRGPNRSHQK----TKDKELLDLKRLLSMITAPISKQAS-----SLSQSKGHKSQTSTNVPEHRKN-----ATEASELENFSVTYRKQRYFNDQPHHRLFLDIFTALINNRLGCSDWLENSSSDNVLRVLNCLRLLIRDPLHQKAFFELQGASQLVKHMESVASVYLECGEQTLEIEQLVAMTYIFQKLSTVEEQRQWIINCEAHKTLVKLLSTRDCSVVLGALLALTTLAESQECKEKIGELSVVEHLLDVLQDYDMLSKRLSAELLRLLCSVQCVRDQLRQCDGVPVLLSLLHSEHIKLLWSTVWVLVQLCQDPDTSAEVRAWGGVQQLLRILHG---------------------------------ERVYVSDRSTIDSISSANAAGRIHSQQVSAVVCAHETAENTISLQSACCAAITELVLDDTTAHNVVQENGVYIIAKLILP-QNGKEPQAKSLQCYAFRALRFLFSMERNRHHFKRLFSPDLFEMFIDVGHYVRDITAYEPLQQKIMLLSPEELDILRESIETVNQNRPPIRVVNGYAVLEHLGSGAFGSVFKVRKQNGQNILALKEVNFHNPAFGKDKRSRDSSVEKIVSEMTIIKEQMSHPNIVKYFKTFLEGDKLYIVMELIEGAPLAEHFSSLKEKKQTFTEERVWNIFIQICLALRYLHKEKRIIHRDLTPNNIMLGERDKVTITDFGLAKQKQENSKLTSVVGTILYCCPEIVKNEPYGEKADVWAAGCILYQTVTLNPPFYSANMLSLATKIVEAVYEPLEDKTFSERVTDMIKWCLTPNADVRPDIIEVSSRISDIMMRFVDSLCVSHNALERRAERDRKRAQKYFLESNRTRMCGPIQQGLSLKNQDESQSESFETSTS----------------------------------VLVVGGEQKQSQVSQCGVKGADELNMS-------------------------SG--------DFQK---PKARP---------------------------------------------------------ASAGICLSQRKVRQIDDPNQRLLELLHKIIFITQLPPAPQNSFKQRAIERFKKSLFIYGSDAYNLKVELNKVLQGSQELVEMSSASREWWSMIQSLSSDPSNAENRESGYS--SLQDGLTYEDIQSMVEDVLEENGYY---SRRDLDSGAATRQTQTP----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ** * : ::: :* . :: ***** .::.. *** . :*.. **:.: .. ** . :*** ******:.*:::* *..:*:::** :*****:.*** . :*::.:.* :.**** *****:*** :*: :..* * .:*.::** **. ** .*: :::** ********::*::**:*: . ******.**.:** .*:**:****::**** **:***.**.:**:** :*::**:*****:********: :::*:: :*:*:*******:*:***** :*:***:*:**:**.*:* ***::***:**:* :* :***:*:*.*:*********:. ::* :.. * ***.***:*****:***.*:**.**:******** ******* :: : .::: *******:*********** *****..**** ***:******* ** * .:: ** :**. : *.**::**::.*:: :..**:*:********.*:****:.***:**:****:*********:.*****.:****:******: ***:*:*:*****.*:*************.***.*****:: *:***:*:****:*************:************::****:***********.*****:******.***::*.***********.****** .**.*** *:****************: : :**:**: * ****:*:.****:**** ***:**:::* *..*: :**:: **:*:*:*:**:*:**. : :: *:: .:: :. *:.:*:* * .. : :. .: : :**::* ** ** .:.** *****.:******** ** *::* ***:*:******* ::.:*:*.********* *:. *** *:.*: *** * :* . : :: : :* .. ...: . : .:::*:***::*:::*:****.*** :.* ", "identical_positions": 568, "similar_positions": 301, "identity": "46.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-573", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D3S5-1", "uniprot_id": "NXRD1_MOUSE", "id": "Q9D3S5-1", "name": "NADP-dependent oxidoreductase domain-containing protein 1", "aln": "-MEMLEDLESLRFEFGIPEEERYWLYLQGRYRGLMIKGCAHAAFFCKMFSTLSNLLQNLPRTIHPRTVSFDNAATEDELLTVGIIGCGHLGKQLTNVLLKTVPIPAENLQISTRRPESLGELRKLGVRCVYDNAAVASWAKVLFLCCLPAQLPNICLEIQSKLNKHCTVYSFVSAIPLPRLKSLLNHTNILRPQYQFA--EDYDNIWGENEEVPIALQDTTIIRGTCPYNNLGGVILNVKWIEGLCYALINACTSRSVFHSQVLKLLNKLLLPMHLESCTTDPESCPQFNLTDFMSKSYVKNLYQKRPFPWFDLTTVQLKETPFSQHISATPSLQDHISLLYCEVFGLTISEEELPYISTVIRPLVEEK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NXP6-1", "uniprot_id": "NXRD1_HUMAN", "id": "Q6NXP6-1", "name": "NADP-dependent oxidoreductase domain-containing protein 1", "aln": "-MDMLQDLESLQFEYGVPEEDRIWLYLQGRSRGLMIEACAHATFFCKLLYNLRASLNKNQSSRHLSIGSLN-SATPEEFK-VGIIGGGHLGKQLAGTLLQLGPIPAESLRISTRRPETLGELQKLGIKCFYHNADLVSWADVIFLCCLPSQLPNICVEIYTSLEKASIVYSFVAAIPLPRLKLLLNHTNILRPQYQYD--EDSVSVWGANKGVIAALQDPTILQATCPYSPAGGIILNIKWLEGVFYAALNICTARNMAHSQVLQLLSELFLSVHFEDCGKDTASCPKLQLTDFVSKAYGKNLSQERPFPWFDLTAVQLKETPFSQHLSSSPVLQDHLTHLYCASFGISLTKE-QPVISTGFPSQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B659-1", "uniprot_id": "A0ACD6B659_DANRE", "id": "A0ACD6B659-1", "name": "NADP-dependent oxidoreductase domain-containing protein 1", "aln": "MLDLTVNLSSLGFESGLSEDEKELLFLRSRSVGLTISGCAHAVFVCELFSLLRKKLNAEN------------GCVNKAHLSVGILGGGNMGKQLAMALIRTSNLRSCDINLSTKRPETLGEISNMGVECYFDNIRLAKWADLLFLCVLPSHLPQVCSDIHCHLPSNCLVYSFTSAVPLNRLLMLLDHNFIIKPQYKFVDYDDVTSVWLLHNQVCTALKDKLVHSATVPLSMKGGLFLDRRWTSAVLYALLNMCTAEKLDSGNTLQLLNGLFETG----VSTETFTYHSFVNSPNATSDVHK---PDELFPWISLVNAQTKDTPLTDLLSRNSVR----IYKVADFLGVKRYLSDSTVASTTFFKLS---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: :*.** ** *:.*::: *:*:.* ** *..****.*.*::: * *: ... . ***:* *::****: .*:: : : .:.:**:***:***: ::*:.* :.* :..**.::*** **::**::* :* * . . ****.:*:** ** **:*. *::***:: :* .:* :: * **:* : .* * . **::*: :* ..: ** :* **:..: .:.*:**. *: . .:. : .: : :. * .. ***:.*. .* *:**::: :* .. . :*:. . . ** : ", "identical_positions": 104, "similar_positions": 126, "identity": "28.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-576", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IWH7-1", "uniprot_id": "ANO7_HUMAN", "id": "Q6IWH7-1", "name": "Anoctamin-7", "aln": "MRMAATAWAGLQGPPLPTLCPAVRTGLYCRDQAHAERWAMTSETSSGSHCARSRMLRRRAQEEDSTVLIDVSPPEAEKRGSYGSTAHASEPGGQQAAACRAGSPAKPRIADFVLVWEED---LKLDRQQDSAARDRTDMHRTWRETFLDNLRAAGLCVDQQDVQDGNTTVHYALLSASWAVLCYYAEDLRLKLPLQELPNQASNWSAGLLAWLGIPNVLLEVVPDVPPEYYSCRFRVNKLPRFLGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKNLLGIHQLLAEGVLSAAFPLHDGPFKTPPEGPQAPRLNQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTLVFLVGCFLVFSDIPTQELCGSKDSFEMCPLCLDCPFWLLSSACALAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKSATLAYRWDCSDYEDTEERPRPQFAASAPMTAPNPITGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYRAIMAIVVSRSGNTLLAAWASRIASLTGSVVNLVFILILSKIYVSLAHVLTRWEMHRTQTKFEDAFTLKVFIFQFVNFYSSPVYIAFFKGRFVGYPGNYHTLFGVRNEECAAGGCLIELAQELLVIMVGKQVINNMQEVLIPKLKGWWQKFRLR---SKKRKAGASAGASQGPWEDDYELVPCEGLFDEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILAGLTHLAVISNAFLLAFSSDFLPRAYYRWTRAHDLRGFLNFTLARAPSSFAAAHNRTCRYRAFRDDDGHYSQTYWNLLAIRLAFVIVFEHVVFSVGRLLDLLVPDIPESVEIKVKREYYLAKQALAEN----EVLFGTNGTK--------DEQPEGSELSSHWTPFTVPKASQLQQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q14AT5-1", "uniprot_id": "ANO7_MOUSE", "id": "Q14AT5-1", "name": "Anoctamin-7", "aln": "------------------------------------------------------MLRGQAREEDSVVLIDMASPEAGNGCSYGSTAQASEAGKQQVAPSRVGSSAKP-PIDFVLVWEED---LRN---QENPTKDKTDTHEVWRETFLENLCLAGLKIDQHDVQDEAAAVHYILLRAPWAVLCYYAEDLRLKLPLQELPNQASNWSATLLEWLGIPNILLEHVPDTPPEYYSCQFKASKLQWFLGSDNQDTFFTSTKRHQILFEILAKTPYGHEKKGLFGIDQLLAEGVFSAAFPLHDGPFSAVPESSQVLGLIQRQVLFQHWARWGKWNKYQPLDHVRRYFGEKVALYFAWLGFYTGWLLPAAVVGTVVFLVGCFLVFSDIPTQELCHSSDSFDMCPLCSDCSFWLLSSACTLAQAGRLFDHGGTVFFSLFMALWAVLLLEYWKRKNATLAYRWDCSDYEDIEERPRPQFAATAPMTALNPITGEDEPYFPEKNRVRRMLAGSVVLLMMVAVVIMCLVSVILYRAVMAIIVSRSDNAFLSAWASRIASLTGSVVNLVFILILSKVYVLLAQVLTRWEMHRTQTEFEDAFTLKVFIFQFVNFYASPVYIAFFKGRFVGYPGNYHTLFGIRNEECPAGGCLSELAQELLVIMVGKQIINNVQEVLVPKLKGCWQKF------SRGKKAGT--GTHPAPWEADYELLPCEGLFHEYLEMVLQFGFVTIFVAACPLAPLFALLNNWVEIRLDARKFVCEYRRPVAERAQDIGIWFHILTGLTHLAVISNAFLLAFSSDFLPRVYYSWTHAPDLHGFLNFTLARAPPTFTSAHNRTCRYRAFRDDDGHYSPTYWTLLAIRLAFVIVFEHVVFSIGRVLDLLVPDIPESVEIKVKREYYLAKQALAEN----EALLGATGVK--------DDQPPSSEPS-----LGLPA------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FD02-1", "uniprot_id": "E7FD02_DANRE", "id": "E7FD02-1", "name": "Anoctamin", "aln": "-----------------------------------------------------MMKKKKSLVEDSATLIALSDHPEQ---TYGSIEKCAKPQENKNVFSDGVT-----TIDFVLVWEESGSPLKSADGDELSFSSSRDTHRKWRTEFLSKLQEAGLHQEMKEVVQGKTKTTYVLLSAPWNVLCYYAEEISLRVPLQVVTTPISNWSETILEKLHIPNIMAQDVPNYPPDYYTCPFRTTKLERFLGHENKDTFFKTTQRHQILYEILARTPYGALKRGEVGIGRLVSEKVLTAAFPLHEGPFQLPKTQEDPQCLNMRQILHHYWARWACWRKYQPLDHIREYFGEKIALYFAWLGFYTGWLLPAAVVGFIIFLFGIWLMVTDVPAEELCSSGNAFIMCPLCNICSHWNLSSICYTYKAGLLFDNGGTVFFSIFMSLWAVTFLEYWKRTSSILSHRWDCSEFEEIEERPRPEFTALAPMTVRNPVTGAEEPYFPEARRLSRTLTGNMVIILMISIVLIFLMAIILYRTILSIIIYRSQSAFFIFSAGRIASLTGSMLNLLVILLLSRLYTYLAQCLTRWEMHRTQTEYENAFILKVFIFQFVNFYSSPVYIAFFKGRFVGYPGSYNTLLGIRNEDCGASGCLIELAQELLVIMVGKQVISNIQEFVLPKLKTWWHKRKLKPARSQEVIDEPDTNSQINPWENDYQLLVCEGLFDEYLEMVLQFGFITIFVAACPLAPLFALINNWVEVRLDAQKFVCEYRRPVVERAQDIGIWLTILQFISYLAVISNAFLIAFTSDFLPRLFYRYT-AGSMSGYINFTLSVAPANFT-QNEMSCRYRGLRDEKGQNTQDYYHLLAIRLSFVIIFEHVVLLIGRIIDWIVPDIPEEVEIKIKREHYMAKEALAENQSLSKSVLEEMGRQNFELRQRIRTQSPTNNMSPTSEDEAMPAL-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : :: ***..** :: :*** :.::. :: . . : ********. *: :: . . * *. ** **.:* *** : ::* : : . * ** *.* *******:: *::*** :.. **** :* * ***:: : **: **:**:* *:..** *** :*:****.:*:*****:****:**** *:. .** :*::* *::******:***. : * **:*.::****. *.*******:*.*****:********************* ::**.* :*:.:*:*::*** * ::* ***** *..* *** * :** ***:*******:**:**** :******..: *::*****::*: ******:*:* ****. **:** :****** * * *:*.:*:::*:::*:: *:::****::::*:: ** .::: *.********::**:.**:**::*. **: ***********::*:** ************:*****************.*:**:*:***:* *.*** **************:*.*:**.::**** *:* *: . .: *** **:*: *****.***********:***************:*****:****:**********.*********: ** :::*********:**:****** :* :* * .: *::****: **..*: :: :****.:**:.*: : *: ******:***:*****: :**::* :******.****:***:*:**:***** : :: * : *. .: * :* ", "identical_positions": 477, "similar_positions": 219, "identity": "50.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-578", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P40142-1", "uniprot_id": "TKT_MOUSE", "id": "P40142-1", "name": "Transketolase", "aln": "MEGYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKALDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLPEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYRVYCMLGDGEVSEGSVWEAMAFAGIYKLDNLVAIFDINRLGQSDPAPLQHQVDIYQKRCEAFGWHTIIVDGHSVEELCKAFGQAKHQPTAIIAKTFKGRGITGIEDKEAWHGKPLPKNMAEQIIQEIYSQVQ-SKKKILATPPQEDAPSVDIANIRMPTPPSYKVGDKIATRKAYGLALAKLGHASDRIIALDGDTKNSTFSELFKKEHPDRFIECYIAEQNMVSIAVGCATRDRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPMSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYSNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAESLKKDKISIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSAAVVGEPGVTVTRLAVSQVPRSGKPAELLKMFGIDKDAIVQAVKGLVTKG----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29401-1", "uniprot_id": "TKT_HUMAN", "id": "P29401-1", "name": "Transketolase", "aln": "MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQ-SKKKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAIAQAVRGLITKA----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F8S4-1", "uniprot_id": "E7F8S4_DANRE", "id": "E7F8S4-1", "name": "Transketolase", "aln": "MEDYHKPDQQTVQALRNIANRLRINSIKATTAVGNGHPTSCCSVAEIMSVLFFHTMKYRPDDPKNPNNDRFILSKGHAAPVLYSVWVEIGFLKESELLSMCQVDSTLEGHPTPKQQFVDVATGSLGQGLGVACGMAYTAKYFDKSSYRVYCLLGDGEMSEGAVWEAMAFASYYQLDNLMAILDINRLGQSDPAPLQHHVEKYQRRCEAFGWHAIIVDGHSVEELCKAMSQPRHQPTAIIAKTIKGKGIPVAEDKMGWHGKVLSKDMAENVMRDIQSRIMNSNKRMYPASPVEDAPPVSLRNIRMPSAPSYKPGEKVATCKGYGMAVAKLGRYNERVVAMDVDTKNFTFSEIFKNEHPNRFIECYSAEQNMVSVATGCAARERNIVFASGLATFFTRAYDQVRMAAISDSNINLCGSHCGLSVGEDGPAHMGLEDMAIFRAIPTATIFYPSDAVSAEKAVELAANTKGVCYIRTTRPETAIIYNSNEDFHVGQAKVVCQSKEDQVTVIAAGMTLHEALAAAEQLKKERIYIRVIDPFTIKPLDNKTIVDHVRATRGRVITVEDHYYEGGLGEAVCSAIVNEPGFTFQRLAVAQVPRSGKMNDLLKIYGIDRDSITQMVRKMLSSSANAK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.*******.:***:: ******.**:****.*.********.****:*******:*:. **:**:****:********:**:**.* *** *:***.: ::.* *:***.*** *.************.*******.*****:******:*****:***:********. *:****:**:***************::: **:********:**************:.*.:**********:**:**. *** .**** *.*:***:::::* *:: *:*:: .:.* ****.*.: *****: **** *:*:** *.** *:****: .:*::*:* **** ****:**:***:****** *******:*.***:*:*.: *.* :*:*****:**:******:***********:*:*****::*.***:*:**::* :*:*****.*::************:*:***:***.****..****:******* :**:******.**:********** ***::* ***:*********.* *:* .***:**::**********:****.:*:*.***.*. :*** :****** :***::***:*:*.* *: :::.. ", "identical_positions": 432, "similar_positions": 151, "identity": "68.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-580", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M9P0-1", "uniprot_id": "F1M9P0_RAT", "id": "F1M9P0-1", "name": "", "aln": "MTHTPAAGSGAARSVSNGNTEAAGGVAARASRGCRGGDRLGRVASRPCGRLATRDPTALRSSLAPGYPGARGPSGGLCSLHHRLPSSGRRGCSCSAWARARGWRRSGSSRRHAMGNCCWTQCFGLLRREAGRLQRAGGG--SKYFRTCPRGEHLTIEFENLVESDEGESPGSSHRPLTEEEIVDLQERHYDSIAEKQKDVDRKIQRELALQEEKLRLEEEALYAAQREAARAARQRKLLEQEKQRIAQRYHPSS--GDCQSVGPEDDFEASLRNIKSQYEVFRSSRLSSDATVLTPNTESSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRMLPMRERSKTEEDILRAALKCSSKK-GSNPTSASDDSNGLEWENDFVSAEMDDNG-NSEYAGFVNPVLELSESAIKQSDTDQQIR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PYF7-1", "uniprot_id": "E9PYF7_MOUSE", "id": "E9PYF7-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------MGNCCWTQCFGLLRREAGRLQRAGGG--SKYFRTCPRGEHLTIEFENLVESDEGESPGSSHRPLTEDEIADLQERHYDSIAEKQKDVDRKIQRQLALQEEKLRLEEEALYAAQREAARAARQRKLLEQEKQRVAQHYHCSS--GDYQSAGPEDDFESSLRNIKSQYEVFRSSRLSSDATVLTPNTESSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRMLPMRERSKTEEDILRAALKYSSKK-GSNPTSASDDSNGLEWENDFVSAEMDDNG-NSEYSGFVNPVLELSDSAIKQSDTDQQIR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63HQ0-1", "uniprot_id": "AP1AR_HUMAN", "id": "Q63HQ0-1", "name": "AP-1 complex-associated regulatory protein", "aln": "-----------------------------------------------------------------------------------------------------------------MGNCCWTQCFGLLRKEAGRLQRVGGGGGSKYFRTCSRGEHLTIEFENLVESDEGESPGSSHRPLTEEEIVDLRERHYDSIAEKQKDLDKKIQKELALQEEKLRLEEEALYAAQREAARAAKQRKLLEQERQRIVQQYHPSNN-GEYQSSGPEDDFESCLRNMKSQYEVFRSSRLSSDATVLTPNTESSCDLMTKTKSTSGNDDSTSLDLEWEDEEGMNRMLPMRERSKTEEDILRAALKYSNKKTGSNPTSASDDSNGLEWENDFVSAEMDDNG-NSEYSGFVNPVLELSDSGIRHSDTDQQTR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P5Z3-1", "uniprot_id": "A0A8M1P5Z3_DANRE", "id": "A0A8M1P5Z3-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------MGN-CWAHCFGLFRREANRIQRGGGS---KYFRSNTAGEHFTIEFENLVESDEGESSQICPRPISEEEISHLKEHRYAALSDKQVQIDETLKAQLVAEEEKLRLEEEAVFAAQREAARLAKERKLKEGKPQRTKPRSEPESKDPRHKSKASDEDFEVYLQSVKAQSEAFRSNRLSSETNVVTPNTESSWDFTSKT-------DATSLELEWEDEEGMNRMGPAWERSKTEEDILRAALRPGGRQQDSGPTSTSEDSTALEWENDFVSAHPDDSGEHEDSAGLVNPALDTPTEEAENQTADQQER", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** **::****:*:**.*:** **. ****: . ***:***************. . **::*:** .*:*::* ::::** ::*..:: :*. :**********::******** *::*** * : ** : . .. :* ..::*** *:.:*:* *.***.****::.*:******* *: :** *:***:************ * **************: ..:: .*.***:*:**..**********. **.* :.: :*:***.*: . . .:. :*** *", "identical_positions": 162, "similar_positions": 86, "identity": "38.85%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-582", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LXD9-1", "uniprot_id": "F1LXD9_RAT", "id": "F1LXD9-1", "name": "", "aln": "--------------------------------------------MSPVGKMSQVQNGKVYQQIFHAQVQLVQSLAATRKRAAEHSETPKNVKTPMMKKVPLPEGETMTPRQRKWVHSLPNDGVTENPVLYREKEEARKEMERLTEDMIASQEVQGLMDIIVP---EKVSN--LQEYEDHKKRKYLRALASFQEELEQIGVELEPLILEKGKLLLKKISKSDEDVDKLFKNVEIEPDLDSYTIETLLELWEKVAERFMQQKQEIKELDEELLALEFSRADKLKEVLKKYVGIIEKTAYILQPDVYRLIDKEAMAMNQALLGNRRAIAQLLVNLTEATLQQELDNRHRWQSLVDTWKALKKEGLIQRFTEFMASEEIQEPPEVKKELEEMQKNQEVLQKVRLDHLCTICNLLPPNYNKNQLTEWYNSLTSLNKQLDTYHMDSMSLVHFLYEKVWQQCLSRVQECKQQLLEWKAFSEAEAESLVNPTFFLMVGEFQSKVEKQLELLDSSFEILAKDTELKSSDLFRYFQEAVKLWEGHQSVLLTQELELEKRIEQHRQKHNQETQNQETSLDKLLDQLRQQSQEESLKIHMDKARTFLKNMKSRYECFHILLTKEVMEYPGLVLKELNCYSFTLSRHFFIREIFEQNLAGEVIFKFRQPESHERHFMRKIRKLKKKQRERMGAHKGEESVAP----KKSAEDMKEEGSEGSEPSLTEGGPSQEAEEIQGLRETSSEASQDLENLRAPEEREEIGEEEEEEEREDEEIKEEREEEEVKEEREKEEAKEEREEEEAKEEREEEEAKEEREEEEAKEEREEEEEGEEEEEEEEETIREDEEDEDGMNEDELEYYQETYPMGQEE--EVMEEISCEEMEFFTTASGNTYFAFLSVEDEQQIHSRPHSQHTVFFHDSFSNKYIEKVAVPDKLILKIKKRIRAGFFEHLEKWFDQSALNARIVVATKVDELNSELELRLHLHKPRLKQVEKDIHNVRAAELLLHQERLDSHCAGVIETLKKERLMFCQFQEEQAVRSKNFRRKIYDMEHIFLNATKSQKLAHLTNTLHRELLSYVDVIQVSLRSFRQYLEESLGKLRYTNIDFVKHCRLFSEGGNFSPEEVETLCHRLEKEATRIEFVESLIMIHMEKMETEYLDQANDVINKFESKFHNLSSDLIFVEKIQRLMTNLQVNIKCQVAKSNSQAEGLNSSLEQLQQKIQTCQGHRGDKDNVTTDDLLAFVRSWKEKLSQRIKYLNCSLDVVSITQEVFTDTILTDAEMESEIQMSSEALEEEAKVGLVTPESFAQPTRMGRPMIEDPAVDVVRRILQISQAKS--TCPCDKERSQT-------------------------------------VLKRHRYRGDKTLKKALASSSVTSAGSMTRHSKYIRIDRKFQVLGEKPSSQ--VEDFKGIILNLLWESNEHLLVVVEDFYRKEKHPITRPECMYENFDQCADHIGRKILEYHHQADEYHNSCLLELRAQVRRFEELLPQVCWLVTENYKEQHWSKFHASMKEVQEQFEQQQKQLEKEKEENAQKLHPNLGHPTYSSQMESLRIREELRQQKVDQMIYMNQEKMEETAKKYARFFIANLASFTERFLIQLDEVITIDDIQVPRMEPPKQKVSILIRRKLAMLSLEEESEKPLIERGSRKWPGIKPNEITIQS--KILIRRTPSITTLKTTLGHLAAVEARDAVYLKYLALFDKEMKSIQDRFRTLLLESRRWKESWKRSLSTIQTLYLTRPPLYFK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "J3QNE4-1", "uniprot_id": "J3QNE4_MOUSE", "id": "J3QNE4-1", "name": "", "aln": "---------------------------MREPPGLERRGIGPAVKMSPVGKVSQVQNGKVYQQIFQAQVQLVQSLAATRKQAAERSETQKNVKTPMMKKVPLPEGETMTPRQRKWVRSLPNDWVTENPVLYREKEEARKEKERLTDDMIASQEVQGLMDNIVPQLTERVSN--LQEQEEFKKRKYLSALASFQEELEQIGVEMEPLILEKGDLLLRKISKSDEDVDMLFKKVEGEPDLESHTIETLLELWEKVAERFMQQKQEIKELDEELLALEVSRADKLKEVLKRYVGIIEKTSYILQPDVYRLIDKEAMAMNQALLGNRRAIAQLLVNLTESTLQQELDNRHRWQGLVDTWKALKKEALIQSFSEFMASEEIQEPPEVKKKLEEMQKNQEMLQSVRLDHLCTLCDLLPPNYNKTQLTEWYDSLTSLNKQLDTYHMDCMSLVHFLYEKIWQQCLSHVQECKQQLLNWKAFSEAEAESLVNPTFFLMVGEFQSKVEKQLELLDNSFEDLARETEWQSSDLFRYFQEAVKLWEGHQSVLMTQELELEKRIEQHRQKHNQENQNQETLLDKLLDQLRQQSQEESLKAHMEKARTFLKNMKSRYECFHLLLTKEVMEYPGLVLKELNCYSFTLSRHFFIREIFEQNLSGEVIFKFRQPETHEKLFIQKIRKMKKKQRKRKGEESIGQDLGS----EKPTESMKEEGSGESEPSTAGEALNQENKSPQ------SDRVSEPRDGPSQEAEETLGVRETSSETS-----QDRENLKVQEEKE--------------EIEEEEEEEEEEEEEEIKEERVEEEEKEEEEEEEEEIKEDEEEEDEYENEDVLEYYQETYFMGQAESREESDEIPYEEMEFFTTTSGNTYFAFLSVEDEQQIHSRPHSHHNLLN--SFCTKYIEQVSIPQKLILKVKKGLRAGFFEHLEKWFDQCVLNARIIVASKVDELDSELELRLHLHKPRLEQVEKDIHNVRAAELLLHQERLDSHCAGVIETLKKERLMFCQFQEEQAVRSRNFRRKIYDMEHIFLNATRSQKLVSLTKTLHRELLSYVDVIQVSLRSFRQYLEESLGKLRYTNIDFVKHCRLFSEGGNFSPEEVETLCHRLEKEATRIEFVESLIMIHMEKMETEYLDQANDVINKFESKFHNLSSDLIFVEKIQRLMTNLQVNIKCQEAKSNSQAEGLNSSLEQLQQKIQTCQDHRGDKDIVTTDDLLAFVRSWKEKLSQRIKYLNCSLDMVSITQEVFTDTILADTEVESDMHMSMEALEEDVKVGLVTPESFAQPTRMGRPMIEDPAVDVVRRILQISQAKS--TCPCDKDRSQT-------------------------------------ALKR-RYRAEKALKKALASASVTSAGSMTRHPKYIRVDKKYQVLGEKPTSQ--AEDFKGIILNLLWESNEHLMVVVEDFYRKEKRPVTRPECMYESFDQCADHISRKILEYHRQADEYHNSCLLELRAQVRRFEELLPQVCWLVTENYKEQHWGKFCASLKEVQEQFEQQQKQLELEKDENARKLHPNLGHPTYISQMESLQMAEELRQQELNRMIHENQEKMEEFAKKYARFFISNLASFTERFLMQLDEVITIDDIQVPRSEPPKQKVSILIRRKLAMLSLEEESEKPLIERGSRKWPGIKPNEITIQN--KILTRRTPSITTNKTTLGHLAAIEARDAVYLKYLALFDKELKGIQDHFRKLLLESQRWKESWKRSLSTIQTLYSTCSPLQLK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P1Z9-2", "uniprot_id": "CC180_HUMAN", "id": "Q9P1Z9-2", "name": "Coiled-coil domain-containing protein 180", "aln": "MRGGENRPPARVQSSSEELELRHQSLDAFPGRRLPGRGIQPAAKMSSVGKVTQVPNGKAYQQIFQAEVQLVHSLAATRKRAAERSVTLKSGRIPMMKKVETPEGEVMSPRQQKWMHSLPNDWIMENPVLHREKERAKREKARESENTIAAREVRGLMDTIVP---EKISTSTFQRQAEHKRKSYESALASFQEEIAQVGKEMEPLIVDTGGLFLKKLTESDEEMNRLFLKVENDTNLEDYTIQALLELWDKVAGRLLLRKQEIKELDEALHSLEFSRTDKLKSVLKKYAEVIEKTSYLMRPEVYRLINEEAMVMNYALLGNRKALAQLFVNLMESTLQQELDSRHRWQGLVDTWKALKKEALLQSFSEFMASESIHTPPAVTKELEVMLKTQNVLQQRRLKHLCTICDLLPPSYSKTQLTEWHSSLNSLNKELDTYHVDCMMRIRLLYEKTWQECLMHVQNCKKQLLDWKAFTEEEAETLVNQFFFQMVGALQGKVEEDLELLDKSFETLADQTEWQSSHLFKYFQEVVQLWEAHQSELLVQELELEKRMEQHRQKHSLESQVQEAHLDRLLDQLRQQSDKETLAFHLEKVKDYLKNMKSRYECFHTLLTKEVMEYPAIMLKELNSYSSALSQYFFVREIFEQNLAGEVIFKFRQPEAHEKPSQKRVKKLRKKQGSKEDMTRSEESISSGTSTARSVEEVEEENDQEMESFITEEVLGQQKKSPL------HAKMDESKEGSIQGLEEMQVEREGSLNPS-----LNEENVKGQGEKK--------------EESEEEDEKEEEEEEEKLEE--EKEEKEAQEEQESLSVGEEEDKEEG-----------------------LEEIYYEDMESFTISSGNTYFVFVPLEEEHCRKS-HSTFSAMFINDTSSAKFIEQVTIPSRLILEIKKQLRAGFFEHLEKWFDQCSLNTRVTVATKINELDSELELHLHLHQPRAQQIEKDIHNVRAAELLLHQEQLDSHCAGVTETLKKKRLMFCQFQEEQNVRSKNFRLKIYDMEHIFLNATRSQKLVTLSNTLHQELLSYVDVTQVSLRSFRQYLEESLGKLRYSNIEFIKHCRLFSEGGNFSPKEINSLCSRLEKEAARIELVESVIMLNMEKLENEYLDQANDVINKFESKFHNLSVDLIFIEKIQRLLTNLQVKIKCQVAKSNSQTNGLNFSLQQLQNKIKTCQESRGEKTTVTTEELLSFVQTWKEKLSQRIQYLNCSLDRVSMTELVFTNTILKDQEEDSDILTSSEALEEEAKLDVVTPESFTQLSRVGKPLIEDPAVDVIRKLLQLPNTKWP-THHCDKDPSQTGRGAWACGSRGSSEAGAGGAVCSPPVLCSCPGPSSPKGFKRHRCQPENSGKKAVPSASATSAGSFTPHPKPNKMERKYRVLGDKPPPA--AEDFKGIILTLLWESSENLLTVAEEFYRKEKRPVTRPDCMCDTFDQCAENISKKILEYQSQANKYHNSCLIELRIQIRRFEELLPQVCWLVMENFKEHHWKKFFTSVKEIRGQFEEQQKRLEKRKDKNAQKLHLNLGHPVHFQEMESLHLSEEERQEELDSMIRMNKEKLEECTRRNGQVFITNLATFTEKFLLQLDEVVTIDDVQVARMEPPKQKLSMLIRRKLAGLSLKEESEKPLIERGSRKWPGIKPTEVTIQN--KILLQPTSSISTTKTTLGHLAAVEARDAVYLKYLASFEEELKRIQDDCTSQIKEAQRWKDSWKQSLHTIQGLYV--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RNE9-1", "uniprot_id": "A0A8M1RNE9_DANRE", "id": "A0A8M1RNE9-1", "name": "", "aln": "-----------------------------------------------MADTRVLPSGKVYRQMFDAQVQLSLALYDSRRKRAADE----------------GDGDGLLSGDAADSASQHHNGTYN----TATSQNFLYSGEKRTEDQDDSEVVCGLPDIIVP---DKKNSDIIDRLKEKRQKDHNEAVSQLQADLSSINLVVEPLFRHTGNDILHRLSEYNDSIERIMQKIESICDLTAHSYQDLHEIRNKVCSESSLKTKLIKQLDEIYSENESKRKAMISALLRKYTSKLEKISYVMPCDVHRLIDNEAMMINQALLANRRALAKLHLNLMEKHLQMDVFQRLKWEEKLQDWKRIKLSDAISQFKDFMNSPQVQNPKNIQDTLRTLKSEQKTLSEKRIQTLEVLREMTPPRISKSSVSEWFSALSVINEQIDHIHVATMETLHKMYDNNWQVCLAEVDLFKTEMSTCG-FTSDEIQNFVNTDVLPLIGPCQSQTEIYLEKLDKAFESLAKTTADESKCLFRLMCGAAQLWEIHCKGLLSREQQLQNSLEVISQVHEQENQRKEAQLDMMLDKLRQEGSEEALKASLEKILTYLEEVKNGYAQTYEEEVEIVEYYPSTVLQELQAYSLSVSQFFGAEEVYGQDHKDFCQIYPSLKLDQNIKTGKNIRHKDAPKSHFNNQESSNFDLSCAT-DDQHCTALAFSFSNTKETLITAKG--------------------------------------------------------------------------------------------------------------------------------------------------------------NVYSCSGFHTTNDEEEEK------------------NLKEIELVLYPKTFTVEVLKEVRQTFFSTLEERFHIILTNTTAIVEAKKEKLKAEFNLRVQLHQTRAARIETDIYIVRAAELAHHRERVDQHCRGIQQVLENSQTDLQELQVQLNKLTEDFQMQIYKREKDFIVGTSSEKLNRLWNSLQSSLDKLISVIQISQRDFRQKIEFRMEGLRESNVQIMRSFKLFSEGGNFTPQEIEVFQSQLEKMDKRIDTAEGAVIQDMEDRESKCLDQAKDIFRRFGEKFSFHANDLKFLEKMQQIFTNTRVQIKSEALKSNMQKKMIDSMLRDLKQMTAEYYQPCPDKKIVTVVEITSLTTSLMEELKKRCQYLDCFLDAS------MAAPRPETPFQGAFAVAARSRSRTQETTGSPEREGLLHPSRIGASFLDDAAVGVIKGLLKVGKAQDLKEDNCDSAEQRASSARLN----------------------SPHGSGRRSGKSLSQSGIETVRRKSVESINIQSSISVKRLPKLNRFDKKYLIFGSNPEEQKNSVCFKTSITGILWKANDILLMVAEEFYKKERRPITRSEQLQETFDQCAEEIQKRLLVYQSQAHDYHNSCLQEFQRQLKAIEEFLSSVPEILFSKLRDQHLEELTQSMIQIQHRFKLVQQRSEQNRREHSGQLRVRLSHPACERELKALVEAEEQRQRHHREAIQHTRQELQACVIKNAEESVTAFARLAEALLFQFDNLITIHEVQVGHAEQ-KENFTTLLRQTQTGL-LQEDTSSAVIQKGSRIWPGICYFGFTDGSSEHKQSQGTATITTAKTTLAHLKTIEVRDTMHERYGQRVQEELDRAHRECDAQEKELQQWHEHWQSQLKSLASLNSE-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. : .**.*:*:*.*:*** :* :*:: * . :*: : . : * :: : .:. . : ::: :. * ** * *** :: .. ::. : :::.: *::.:* :: .:. :***: ..* :*::::: ::.:: :: ::* :* :: : * *: :**. . :.: **:*** * .* :. :*::*. :** :*:: :*:***::*** :* ***.**:*:*:* :** * ** :: .* :*: :: ** :* . :. *.:** * .:: * : . *. : . *: *.. *:. * .: :: ** .*..::**..:*. :*:::* *: * :: :*:: ** ** .*: * :: *:. * :.:** .: ::* *.:.* ** **.:** ** * :*. **: : ..:*** * . *: :* :*:: :* * *. *.* :*: ** :**:***:..:*:* ::* :*:::*. * : .: * **. :*:**:.** ::*:.* .*:: *: . : :: :.::: : . .:. : : . . *. : . * . :.. *:*: * ** * *. : ::: * :* **. **: *. *: * :* ::*.:*::*:::**:.* ::*.**: ****** *:*::*.** *: :.*::.: : ::* : :.:*: :**. *: *: .* *:** * ::*: .* . :.* *:* *.*** :* : ** :*::::: :********:*:*:: : :*** **: .*. :: .**. *.: ****:*::.:* .** : ** *:**:*:::** :*:**.: *** * : :: *.:*:: :* **. :: ::. : *:*.:* :**:* ** :: . : : . . : . . *.: : :*:* .:::*.**.*:: :*:: ::: **. .:: . : :. :*:: * . *: *.. .* :.::*: ::*.:* ** * :**::.: *: *.*:**:**::*:**.: : :.*****:.* :::* *: **..****** *:: *:: :**:*..* :: .: :::* :: *: ::: :*: *:: * .: ::: :*: .*.**. ::::* ** **.. * .::::: . : .. :: :* ::* :*:*:*:::**.::** : * *::.: *:*:. : * *:*::...:*::*** **** .* . : : *.:*:* ****.** ::*.**::: :* .::*:. : * ::*:: *: .* :: * ", "identical_positions": 390, "similar_positions": 560, "identity": "22.06%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-586", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M0N9-1", "uniprot_id": "A0ABK0M0N9_RAT", "id": "A0ABK0M0N9-1", "name": "", "aln": "--MMYFDCIIPGEEGSSVS---------------------KDTDVNKRAS--LPA-EHPDLPDGPLPGSASDGEKKVRLSPGKMSTKNSTELVEYVDKGCPFLPAMPSNQTSQLQDRLNNQERTIAFLLEQAFRIKEDISACLQGSQGFRKEESLARKLLESHIQTITSIVKKLNQNIELLEDQIRIRDQVATGTNFAVQDLNIKHIQGVGDLRGRVARCDSSIVKLSGDMQFIRHECRQTEKSVQELASAIETISKNLDVKVMQLLGKIEASTSEHTSNLKTVQGDYQHEMNLLDFKFNSLSTNIYEEVENNQKWTENQFIKYRKDHLGHMNECLKVVQEKLEKSENKMEEKMLQLSSKLENFINSQKQEAEVNKVKAIENKVSKKMCQIEKRIWGELEKMQNDYQSGFKSIHDSLNSLQQIQKTKMDLEKYKVQKDLKKLQRKIVELQEV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A140LI28-1", "uniprot_id": "A0A140LI28_MOUSE", "id": "A0A140LI28-1", "name": "", "aln": "--MMYFDCIIP-EEGPPFSSIHLH---------------SVETDVNTSAS--LPAEEQPDPPDGPLPGSVIDQEKKVRLSPVKMSTKNATDLVEYVDKGCPFLPAMPSNQTSQLEDRLSHQERTVAFLLEQAFRIKEDISACLHGSQGFRKEESLARKLLESHIQTITSIVKKLNQNIELLEDQIRIRDQVTTGTNFAVQDLNIKHIQGVGDLRGRVARCDSSIVKLSGDIQFIRHECRQMEKSVQELASALETISKNLDVKVMQLLGKIEASASEHTSNLKMVRGDYQHEMNLLEFKFNSLSKNIYEEVETNQKWTENQFIKYGKDHLSHMNECLKVVQEKLEKSENKMEEKMLQLSSKLENFMNSQKQEAEINKVKTIENKVSKKMSQLEKRIWGELEKMQNDYQSGFKSIHDSLNSLQQIQKTKMDLEKHKVQKDLKKLQRKIVELQEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96LP2-1", "uniprot_id": "FA81B_HUMAN", "id": "Q96LP2-1", "name": "Protein FAM81B", "aln": "MQLQFLGTLASSEKRKKSQRLFFKNIKSTKNKAGKASIMSSDTNVNKSASPTATAEEQPVEPDGPLPGSDNNQEKKVRLSPAKMSTKNSTDLVEYVDKSHAFLPIIPNTQRGQLEDRLNNQARTIAFLLEQAFRIKEDISACLQGTHGFRKEESLARKLLESHIQTITSIVKKLSQNIEILEDQIRARDQAATGTNFAVHEINIKHLQGVGDLRGRVARCDSSIVKLSGDIHLFRQEHRQIEKAIQEFVPALETLSKNLDMKVMQLLGKIETASSEQTSNLKMVQGDYRHEMNLLEFKFHSLSSNLYEEVENNKKWTENQFLKYRKDHLGHINECLKVLQEKLEKSENKMEEKLLQLSSKVENFINTQKQETQLSKVKHMENKLSKKMEQMEKQIWGELETMQNEYQSGFKSIHDSLSSLQQIQKTKMDLEKYKVQKDLKKLQRKIVELQEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ASS7-1", "uniprot_id": "A0A8M3ASS7_DANRE", "id": "A0A8M3ASS7-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------MHIGYMERRVTNQEHTLNSLLEKAMKIRDDVVTGLHAAQGSALMESSARKLLENHIQIITHIVKQLSKDIQVLEAQIMERDNLAAGTTFAVKSLDHKNMMGIGDLRGRVARCDASIAKLSSDVGAEQQDILKLKQEVNELHSKLELKMKDMELKLSRDVGKLETSLSEKLISQRNTIADLHKEIQLLDVKSSSGVKEVEEQTVRLRKWFEEQMKTALQSHTQNSQQLQTLLQDRLVEMEGKQKENMVILSGHLERFEAALEKVRSADRIKRSESKIYNKMNILENSFREDLEQMRREYQSGFQTVHDAIESLRHISDTKAKLDKEELQRDIREMQRNMEKL---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :: *:.:* :*: ***:*::*::*: : *:.::* ** ******.*** ** ***:*.::*::** ** **: ::**.***:.:: *:: *:***********:**.***.*: ::: : :: ::*: . :* *::::*: : :**:*:: **: . : . .* ::*::**:.* * .:: *:. :** *:*: . :.* : :: .::*::* : *.* :*::: **.::*.* : :: . .::* *.*: :** :*: : :** *:.:*****:::**::.**::*..** .*:* ::*:*::::**:: :* ", "identical_positions": 117, "similar_positions": 142, "identity": "25.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-589", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H9D4-1", "uniprot_id": "ZN408_HUMAN", "id": "Q9H9D4-1", "name": "Zinc finger protein 408", "aln": "MEEAEELLLEGKKALQLAREPRLGLDLGWNPSGEGCTQGLKDVPPEPTRDILALKSLPRGLALGPSLAKEQRLGVWCVGDPLQPGLLWGPLEE--ESASKEKGEGVKPRQEENLSLGPWGDVCACEQSSGWTSLVQRGRLESEGNVAPVRISERLHLQVYQLVLPGSELLLWPQPSSEGPSLTQPGLDKEAAVAVVTEVESAVQQEVASPGEDAAEPCIDPGSQSPSGIQ---AENMVSPGLKFPTQDRISKDSQPLGPLLQDGDVDEECPAQAQMPPELQSNSATQQDPDGSGASFSSSARGTQPHGYLAKKLHSPSDQCPPRAKTPEPGAQQSGFPTLSRSPPGPAGSSPK-------QGRRYRCGECGKAFLQLCHLKKHAFVHTGHKPFLCTECGKSYSSEESFKAHMLGHRGVRPFPCPQCDKAYGTQRDLKEHQVVHSGARPFACDQCGKAFARRPSLRLHRKTHQVPA---APAPCPCPVCGRPLANQGSLRNHMRLHTGEKPFLCPHCGRAFRQRGNLRGHLRLHTGERPYRCPHCADAFPQLPELRRHLISHTGEAHLCPVCGKALRDPHTLRAHERLHSGERPFPCPQCGRAYTLATKLRRHLKSHLEDKPYRCPTCGMGYTLPQSLRRHQLSHRP-----------------------------EAPCSPPSVPSAASEPTVVLLQAEPQLLDTHREEE---------------VSPARDVVEVTIS-----------------------------ESQEKCFVVPEEPDAAPSLVLIHKDMGLGAWAEVVEVEMGT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "H7BX78-1", "uniprot_id": "H7BX78_MOUSE", "id": "H7BX78-1", "name": "", "aln": "MKEVEEVILG--KIEPHPPEPPLGQDSGWSPSGKGFAPGLKACPPGTSPAILVLRSLPQGLAVGPSRSRNQHLGVWCVGAPLQPGLHWGPLED--ESVLE-KGEGMKTPHEEDFSLAPCGAICPRQQSSTWTSLVQEGRLQSDGNASLVWIREKLHLQVDQTILPGFELLLRPQSPQKSLSVLHPKLEEEVA---ETGEASATQEEVASPQEDSAGFCTDPGHESSHSIQ---EDNMLVSESVTKTEEQLFKDSQPIGLLLHDDSMDKQC--LPQTPPEPQSTSAAQKSPESSEAGLFPPE-GAQVETCPAKQLDVPSSQCPSIAQTSEPGTQLPDLSGLLCSPLDPAGSSSK-------LGRRYRCGECSKAFLQLCHLKKHAFVHTDHKPFLCTECGKSYSSEESFKGHMLGHRGVRPFPCSQCDKAYGTRRDLREHQVVHSGARPFVCEQCGKTFARRPSLRLHRKTHQMPD---APSPCPCPVCGRLLATRGSLRNHMRLHTGEKPYLCPHCGQAFRQRGNLQGHLRLHTGERPYQCPHCANTYPQLPELRRHLISHTGEAYLCPVCGKALRDPHTLRAHERLHSGERPFRCPQCDRAYTLATKLRRHLKSHMTDKPYQCPICGMGYVLPHSLKRHQLSHQC-----------------------------GVSSSP-SLPPAASEPPMVLLQSEPELLDTCSQQE---------------VPPGEGIVEVTIS-----------------------------ESQEKCFIVPEQPAPSPSLVLIHKDVGFRGWAEVVEAEAGT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FAN3-1", "uniprot_id": "E7FAN3_DANRE", "id": "E7FAN3-1", "name": "", "aln": "----------------------MSTVTGRNEGSGNKRDSIHS----------ALRSVPLGLTVGPSLAEDEQLGLWCVGRVLKKDTLLG-LEEPGETISKEKEEGLQNASQSVYKREISDEVC-------WMQFACSAQSAEESNVSVLKVDGRLGLKVCRDIQPGTELLLWESHPEAVTEEETPQVETCENRE-QDEALEANTSDHFSGSPYLLQRVTQQDTKSPVTVKGLVQDNTICNSNVLEQNGMEESEAEHSDELPATEEIESIN--VSASQAQTSSQCLTPERSLRTSSRLASKPRKVHSSAKRIYKRHDPKNKPDLSSKKKLLNSKDDLMQPLTVKEESSTKQNGQDFPPFNIRERKYKCEECDKSFFQLCHLKKHKYTHQNQKPYTCTECGKSYSSHESFQAHLLMHRGQRPFKCEQCDKSYGLKRDLKEHQVLHSGEKPFVCDICGKAFARRPSLRVHREIHRTKEPDYQALKVKCPECDKELANSGSLRNHMRLHTGERPHICPHCNKCFRQRGNLQGHMRIHTGEKPYRCDHCDLRFSQVPELRRHLISHTGEVYLCPVCGKALRDPHTLRAHERLHTGDRPYKCEQCGKGYTMATKLRRHLKSHLEEKQHVCQVCGAKYSMMQSLQRHLQLHQPDSGHALPTRGRPKRLGQKEEEEPGRTESSGLEAGQAVACAQASDHLTMVTHTEGIILDSGTYQHGTIVLGKGAEKELDRIELSEDIIEIFISDENTNIVVQEQTSKGLSLQEQEVNAECTVEASSDCIVLPEQ-DANSCLVIIQGQDGLSSVAETVEIETVV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * . .. . .:: .*:*:* **::*** :.:::**:**** *: . * **: *: : * **:: :. . . :* * .:. .: .:.*.: : : :* *:* : : ** **** . .. . * :: .* .: * : . :*. :: :* : : .::: . * .::. . .: .* . : : . : : : . .: : . *..: ::. .:: : * . ..: .. : *:*:* **.*:*:******** :.* .:**: **********.***:.*:* *** *** * ****:** :***:****:*** :**.*: ***:********:**: *: . ** *.: **. *************:*.:****.:.*******:**:*:****:**:* ** :.*:*************.:**********************:*:**: * **.:.**:***********: :* : * ** * : :**:** *: .. . **: :: ::* :**: :. : ...::*: ** *:...*:::**: . ..**:*: : *: . **.** * .", "identical_positions": 245, "similar_positions": 204, "identity": "30.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-591", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WBQ1-1", "uniprot_id": "B1WBQ1_RAT", "id": "B1WBQ1-1", "name": "", "aln": "MNPAGTGPTVSSGGESTDVSLGPPFPWPCPPDVRLCGHLRKQKSQRRRFFVLRAD----PPRLECYESEKKFLASGCRPPRPRRTVSLEGACTISKRADARQRHLIVIYTSDSSLGVAAASEAEQQTWYSALLEVRATAAAAAATAMGFSPQEAPESWIFAPFQDVWPVTLRSKGLGRAPGLSSGSYRLCLGSGALSLLRKPGSKGSRDSRATPPPVLRLSLLSVRRCGHA--DSFFFLELGRSAPIGPGELWLQAPDAVVAQSIHETVLAAMKRLG---------SSAASGKAEAPLGDSPKGASAVPAPAPYEIPALALAAQAR-----SPGERAKQDYVNPLER-------------------------------------------------------------------------------------------------------MGSAPSYRGPDLGGDYIAMGMRNDY------------------------VHMGGKAAEYMWMAPPG--------------------------------------LPPPTPPRVD---PRKEP--EDCESTEYMPMNRFLP---------------GPLYYEFKAREPEHGHSS----------------------------------------------------------------------------------AQCSIRDRWRPTVAQPRSSQGSELSGDYMYIPDYPSARLGSLDSCLN---------------------------------------------------------------------------------------------------------------------------------------------YVDLDLVPPL----EVPGAAPGNSPHSYASIKF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9QHL3-1", "uniprot_id": "A0A8M9QHL3_DANRE", "id": "A0A8M9QHL3-1", "name": "", "aln": "--------------MENHMELQN-----STEDVRRSGYLRKQKSMHRRYFVLRAASERGPARLEYYESEKKFRG---KAPVPKKALALETCFNINKRADSKNKHMIVLYTRAESFVVAAENEADQEEWYQAMVELQCKSKALCENANGGDYGVPSP---GPAFKEVWQVKVWPKGLGQAKNLVG-IYRLCLTEKTVNFVKLN----------SDAVAVVLQLMNVRRCGHS--ENFFFVEVGRSAVTGPGEFWMQVDDSVVAQNMHETLLEAMKALSEE---FRQRSKSQSTAAGAGGGTTASNPISVPSRRHHPNPPPSQVGFTRRPRTEPPGSTAGCNNTSPASRHSFPRTRTSSDGAKVDDGGCATTGEIMPCSSPTTNGSVSNTPILRSTSVRASTPVKAQHALMRSTSTPAPSAAPSMPSGSVHGSEFCATGTGTGNSGGGANGSMYSRLPLRQPSVSGSLSDYGSSDEYGSSPGEHSLLTPTMQAGFTASSGSNSLGDEASNYILMSQRGSSKSQTSQNALPQTRRVLRRSSSRECEAERRIMSKRASLPPMALERLA---PLRRAGEEAVEEDDYAIMNQTSSRESFVARQDSGPSTSGTGYLEVAAEIKGDGGSSDTGITAVIGGAKGAVDNGYMSMLPGVTAPPVSLSHSLSVTVSDSDSKSADDYMAMTPNNSISPPRQIRPPSGTDGYMMMSPNSSCSPDQRGVPTAWIGSSSADSRTGSDYMNMSPISARSANSTPPPPEPHTPSDQHSNQPQPKMVYSYYSLPRSYKHNTSTHFEEGPGRGKHLVNGGKGIGGGRGLCNSKSKHQEPLVGRHLSLSSSSYSSSSASSESLGEGEEKAIKGTGGAAGVTAKDIERGSLQQRQGSGRAKQGHSGHRGRPLSLFVDVNKANTLPRVRETPLLPEPKSPGEYVSIEFKGERNQKAEGNGTRGFRQDASLPPSSHRHLPRPTSCVAGFLQFSQSSSTPIPPSTASEYVNMELGVSLSPSPISLTPLGFPSFPTPPVTPAAAPKAHDEHRSTVLNDIG---AEREMAQRKSRQGSVPQSGDSPTCGDYTKMAFSLNSGSTLSSTSPKSPLLDQPESVVPALGLGLGLDFP-LAKVPNPDHGAKVIRADPQGRRRHCSETFQAPSSLLACPSTSSSSAFPDHTQVISRRLGLDGMLWGNSSSSDVSSQYINPGLSSLSVSQTSSMEQGLNYIDLDLANKESSHASTDGQAAVHTPASRIFSSVLGVGGATGGLVGTGGSGSNASNLNMYASIDFYKSEELRTHQGSSSNSRKDGTGETGAH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9XTN2-1", "uniprot_id": "IRS1_DROME", "id": "Q9XTN2-1", "name": "Insulin receptor substrate 1", "aln": "-----------------MASISD-------DGMALSGYLKKLKTMKKKFFVLYEETSTSAARLEYYDTEKKFLQR----AEPKRVIYLKNCFNINRRLDTKHRFVIVLSSRDGGFGIVLENENDLRKWLDKLLVLQRNIANSNGTAHS-------------PYDHVWQVVIQKKGISEKVGITG-TYHCCLTSKSLTFVCIGPEKTPNGE--DRVASIEILLTTIRRCGHASPQCIFYVELGRQSVLGSGDLWMETDNAAIATNMHNTILSAMSAKTESNTNLINVYQNRPDLSHEPMRKRSSSANEASKPINVNVIQNSQNSLELRSCSSPHNYGFGRERCDSLPTRNGTLSESSNQ------------------------------------------------------------------------------------------TYFGSNHGLRSNTISG--IRPHSTNKHSNSPTFTMPLRCSESEESSISVDESDDNGSFSHYRLNTRSSE-----------------------------------TAIPEENIDDFASAELFSKVTEQNVSDENYIPMNPVNPTDAIHEKEKADMQRLEDASLHFNFPEHASEKLAKDFDLD-------------------------------------------------------------------SDNQCCRPIRAYSIGNKVEHLKFNKRLGHLNDTGQNPNRVRAYSVGSKSKIPRCDLQRVVLVEDN-----------------------------------------------------------------------------------KHEFTANRSQSSITKEGTSYGSSANRQKKSTSAPLLSLKNQINSDRMSDLMEIDFSQATN--LEKQKFIKNNEIPKYIENVFPKAPRTDSSSLTLHATSQKDIFNGTKLNNTAITSEDGYLEMKPVGNGYTPSSNCLPMKVEKLKLSDYQTAPPLTATAAPVHDLNKISTYNISAEKWREQPSRSEEKKSNSPLNDNTFSSKPTNVESTSKSHDVHSANQIDCEKVCAQSSDKLNNHLADKIVENNNLDIGGHEEKKLVHSISSEDYTQIKDKSNDFTKFNEAGYKILQIKSDSSLISSKLYQKGIHKDNLERSQRLTESVNTIPDNATATAVSSSSLTKFNINSAKPAAAADSRSTGTDPSTPQNILQIKDLNFPSRSSSRISQPELHYASLDLPHCSGQNPAKYLKRGSRESPPVSACPEDGNTYAKIDFDQSDSSSSSSNIFNT------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .: .*:*:* *: ::::*** ..*** *::**** . *::.: *: . .*.:* *::::.:**: : .: :. .* : . * . :: :: . .* . .:..** * : **:.. .: . *: ** . ::.:: : : * .:*****: : :*::*:**.: *.*::*::. ::.:* .:*:*:* **. . . : .... .. : . . . : .. : * * :.* :.: ... :.* : . :* . . : .. :* ** . .. : * :: . . . : : . .. :::: . * :. .* . * ", "identical_positions": 64, "similar_positions": 153, "identity": "4.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-593", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZT86-1", "uniprot_id": "NET5_RAT", "id": "D3ZT86-1", "name": "Netrin-5", "aln": "MADYRTLFSPSGTGSAVTVLVALSLLLLLSQATS---------DPCYDPGGRPRFCLPPVTQLVGKAAAPCSQTCALPAD---SPDPVCN-----------------GTLTLDLDGSFLLTSVTLRFCTAGP----PALVLSAAWAIGGPWRPLWRRP-----------------------------------------AWPGVLGGPKKVTFHSPPGPKTRIVASYLRVELGG-----------------------------------------------------------------------------------------------------------------------------------------------------KAGLVTTGVRGRCQCHGHAARCAARAQ-PPRCRCRHHTTGPGCESCRPSHRDWPWRPATPQHPHPCLP---------------------------------------------------------------CQCHPIGATGGMCNQTSGQCSCKLGVTGLTCNHCGPGYQQSRSPRMPCQRIPEATTALATTPVASRSDPQCQGYCNVSVSSVHMNLQKYCQQDYVLHARVAESAQVSASSSLSSLSEAVGPEWWRLAVHVLAVFKQRAWPVRRGSQEAWVPRADLSCGCLRLRPGADYLLLGRAAENHT----DPAHLILNRHSLALPWRPRWAGPLRRLQQKERGGACRGLLPPTRSPGPRN-----------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UQ22-1", "uniprot_id": "NET5_MOUSE", "id": "Q3UQ22-1", "name": "Netrin-5", "aln": "MTDYRTLFSSPGAGSTVTTPITLSLLLLLSQATS---------DPCYDPGGRPRFCLPPVTQLVGKAAAPCSQTCALPAA---SPGPACN-----------------SSLTLDLDGSFLLTSVTLRFCTAGP----PALVLSAAWATGGPWRPLWRRP-----------------------------------------AWPGALGGPKKVTFHSPPGPKTRIVASYLRVEFGG-----------------------------------------------------------------------------------------------------------------------------------------------------KAGLVTTGVRGRCQCHGHAARCATRAQ-PPRCRCRHHTTGPGCESCRPSHRDWPWRPATPQHPHPCLP---------------------------------------------------------------CQCHPIGATGGMCNQTSGQCSCKLGVTGLTCNRCGPGYQQSRSPRMPCQRIPEATTTPATTPVASRSDPQCQGYCNVSVSSVHMSLQRYCQQDYVLHA------QVSASSSQP--SEAVGPEWWRLAVHVLAVFKQRAWPVRRGGQEAWVPRADLICGCLRLRPGADYLLLGRAAQTHDDDNYDPARLILNRHGLALPWRPRWARPLRRLQQKERGGACRGLLPPTRSPGPRN-----------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WTR8-1", "uniprot_id": "NET5_HUMAN", "id": "Q8WTR8-1", "name": "Netrin-5", "aln": "------------------MPVTFALLLLLGQATA---------DPCYDPQGRPQFCLPPVTQLAAVAAS-CPQACALSPGNHLGARETCN-----------------GSLTLALGGPFLLTSVSLRFCTPGP----PALILSAAWASGGPWRLLWHRP-----------------------------------------AWPGALGGPERVTFHSTPGPKATVAASHLRVEFGG-----------------------------------------------------------------------------------------------------------------------------------------------------QAGLAAAGLRGRCQCHGHAARCAARAR-PPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPRMPCQRIPEATTTLATTPGAYSSDPQCQNYCNMSDTRVHMSLRRYCQQDHVLRA------QVLAS-------EAAGPAWQRLAVRVLAVYKQRAQPVRRGDQDAWVPRADLTCGCLRLQPGTDYLLLGSAVGDPD-----PTRLILDRHGLALPWRPRWARPLKRLQQEERAGGCRGVRAPTPSPRPEH-----------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q8G1-1", "uniprot_id": "A0A8M9Q8G1_DANRE", "id": "A0A8M9Q8G1-1", "name": "", "aln": "MSRYHSPPFQTLSFLLLFLFTLFPLSLLSPILSQSPLSWTSPHDPCYHLDGRPRHCLSEFINTAYGVPVTMEDLQQGPKTNISTLTDLHNPHNLTCWTASEGSSGGDWTLIVPLGRRFEITYISLQFCQQVDSVESYSITILKSMDFGQSWRPLQFYSNDCMGSFGRPAQSIALTKHQETEPLCSDPRPLQKHRGNIVLAFSTLDGRPSSPDFDYSPGLQDWVTATDIKIVFHQSMDKMKKQEEKMNEVGGAYRWRERGDKALRFGEKNTGTKATDVWGNSREKQTSTQRFKNKSTVLQSGHNVTRKEMGSQGRVGRGHRKDNSRPCQDGTCDRSLNIQQQSSKGRELRRRRNNGGRGKSHFKQRKNGSRQLVPSSLYAPTKPTLALSDLQVGGRCKCNGHASRCRRDNQGHAVCQCEHHTSGPDCDMCEQFFYDRPWQRATPSQPHPCVPCECNGHSNKCRFSMAVYQQSGRVSGGVCLKCRHHTTGRHCQFCQNGYMRDHSKALNHRKACQPCQCHPVGAVGRWCNQSTGQCLCREGVIGQRCNRCAPGYKQGHSPLRPCIRIQEVAPPTPVYQPQYSIGEECFSYCPPSQARVRMNLETYCLKDYVLKVQVK--------------SKERSGPWWQFSILVQSVFRMGSSHVKRGLQALWVPDRDVSCGCPALQIGRTFLLIGAEESRRSWVP-EERRLVADRTTMALQWREHWSPKLRGFRGQDTRGKCLQGNTTAQKPSHPNSYEEYTPPHLDKLQSVPHRLHKHTHMAHKQHHLTPQSGSEHTHNQRGTQDIQGKNTETHLEEDHEAENVTLSSSQETQDPLSGTSKTSQASKRERYYPTACPTWSPV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* ** : ****. ***:.**. . : . .. : . * :* : *. * :* ::*:** :: : : * .** * . *:. * *. *. .** : :.*: ::: : .* : ***:*:***:** : . *:*.***:**.*: *. . * **: *** :****:* *****:**.* ***::*** *: ** * **:*.***:*.:** ** ** *.:.. .. . :* .** * : *:*.*. ** :*:**:. : . * :::: * :*:: : *:** * *** *: *** *: * :**:* :*: :* :** ** :*: *: :: :: * * ..: .* : ", "identical_positions": 135, "similar_positions": 115, "identity": "15.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-594", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C1Z8-1", "uniprot_id": "TM10A_MOUSE", "id": "Q8C1Z8-1", "name": "tRNA methyltransferase 10 homolog A", "aln": "MSS-EMLPASIESPNVEEKLGTSDGEEERQEPRVDAGAEPISKRQLKKLMKQKQWEEQREQRKEKRKEKRKRKKLERR-QLESNSDGND---RKRVRR-----DVARSSLRLVIDCSFDDLMVLKDIKKLHKQIQRCYAENRRASHPVQFYLT--SHGGQLKKNMDENDQGWVNWKDIHIKSEH----YSELIKKEDLVYLTSDSPNVLKDLDESKAYVIGGLVDHSHHKGLTFKQATSYGIEHAQLPLADFVKMNSRKVLAVNHVFEIILEFLETRDWQEAFFTILPQRKGAVPAHKACESSPQDHQSL---PEGWDS-ASEGESCRDNPDSPQKDEQGQQSSPVLQ------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4KLI2-1", "uniprot_id": "TM10A_RAT", "id": "Q4KLI2-1", "name": "tRNA methyltransferase 10 homolog A", "aln": "MSS-EVLPASIEPPNVEGKPGASDSEEERQKQRVDAEAQPISKRQLKKLMKQRLWEEQREQRKEKRKEKRKRKKLERRCQLESNSDGND---RKRIRR-----HVAPSNLRLIIDCSFDDLMVLKDIKKLHKQIQRCYAENRRASHPVQFYLT--SHGGQLKKNMDENDQGWVNWKDIHIKSEH----YSELIKKEDLVYLTSDSPNVLKDLDESKAYVIGGLVDHNHHKGLTFKQASSYGIKHAQLPLAEFVKMNSRKVLAVNHVFEIILEFLETGDWQEAFFTILPPRKGAVPAHKACESSPQDHQAL---PGGWDS-AIEGEHGRDDPGSPHKEQQGQQSSSVSAVSPDPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TBZ6-1", "uniprot_id": "TM10A_HUMAN", "id": "Q8TBZ6-1", "name": "tRNA methyltransferase 10 homolog A", "aln": "MSS-EMLPAFIETSNVDKKQGINEDQEESQKPRLGEGCEPISKRQMKKLIKQKQWEEQRELRKQKRKEKRKRKKLERQCQMEPNSDGHD---RKRVRR-----DVVHSTLRLIIDCSFDHLMVLKDIKKLHKQIQRCYAENRRALHPVQFYLT--SHGGQLKKNMDENDKGWVNWKDIHIKPEH----YSELIKKEDLIYLTSDSPNILKELDESKAYVIGGLVDHNHHKGLTYKQASDYGINHAQLPLGNFVKMNSRKVLAVNHVFEIILEYLETRDWQEAFFTILPQRKGAVPTDKACESASHDNQSVRMEEGGSDSDSSEEEYSRNELDSPHEEKQDKENHTESTVNSLPH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FBE2-1", "uniprot_id": "E7FBE2_DANRE", "id": "E7FBE2-1", "name": "tRNA methyltransferase 10 homolog A", "aln": "MATGKADEPAVQESHHECANNENEPAKDEKDTLQTGEVETMSKRQRKKLLKSQQWEEQRELRKQKRKERKQQRKLERQAQGDDGVEWTG---KKRLRR-----SAEPSSLRLIIDCSFDNLMVLKDVKKLHKQIQRCYAENRRTLHPAQFYLT--SHGGQLKQIMDEINKGWVNWKDVHVKTDA----FHEILKKEDLVYLTSDSPNVLQELDENKAYVIGGLVDHNHHKGITFNLAQELGIAHAQLPLGSFVKMNSRKVLAVNHVFEIILAFLEKRDWREAFFTVLPQRKGAVPMGQENTLGKDEDEEESDDDSDSEHLSERRTDSKDQSDNKQDEEHKRVPNQPDSTDKNTE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VR56-1", "uniprot_id": "TM10A_DROME", "id": "Q9VR56-1", "name": "tRNA (guanine(9)-N(1))-methyltransferase Trmt10A", "aln": "-----------MDTTEKALKEVTPAMLSLNNCPGTTPGTPMSKNQLKKQRKLAEFAELRKLRREREREKKKQKRREAKELGLPVRTGPS---RKELKKRQL-ADGGKSGLSVAIDLDYDDLMQERDIVKCVKQCLRIYTINRRSPQPGNLHFTGIRRNGHIHESFKK-NEGWENWHVQYYFDRG----HTDIFEHSQLVYLTCESDRVLDKLQPGCTYVIGGLVDHNHFKGLCHSRATSAGLTTARLPLSEHVDMKTRAVLSTYHVFELLTKVAAGQDWTTAILETIPMRKGAKAKITDKKEPNHCLEQQD---------EKQKQEAESDKPTLTAVESEIESHSLDS------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12400-1", "uniprot_id": "TRM10_YEAST", "id": "Q12400-1", "name": "tRNA (guanine(9)-N1)-methyltransferase", "aln": "---------------MSNDEINQNEEKVKRTPPLPPVPEGMSKKQWKKMCKRQRWEENKAKYNAERRVKKKRLRHERSAKIQEYIDRGEEVPQELIREPRINVNQTDSGIEIILDCSFDELMNDKEIVSLSNQVTRAYSANRRANHFAEIKVAPFDKRLKQRFETTLKNTNYENWNHFKFLPDDKIMFGDEHISKDKIVYLTADTEEKLEKLEPGMRYIVGGIVDKNRYKELCLKKAQKMGIPTRRLPIDEYINLEGRRVLTTTHVVQLMLKYFDDHNWKNAFESVLPPRKLDAEAKSASSSPAPKDT----------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :**.* ** * : * : . ..: :::: : * :: ::. * : : :* .:*.** ::: . :* * *: ***: : :: .: : : : : .: **: : :.:..::***.:: . *..*: . *::**:**:.:.* : . * . *: :**: ..:.:: * **:. **.::: :* *: :* ** ", "identical_positions": 46, "similar_positions": 89, "identity": "12.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-595", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VAM2-1", "uniprot_id": "Q9VAM2_DROME", "id": "Q9VAM2-1", "name": "Aminopeptidase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MKCVFLILAALGLSFAGEGS----------------------------------------------------------------TYDHFRLPTALRP-------------------------------------QSYDVRILTQLENPDD--FHFNGTVKIQIE----VLQNTHNITLHSKDLTIDDTEITLSQIGGE-ETTENC--ITSTAVNPTHDFYILNTCKELLAGQFY--ELSLPFSAKLQDQLAGYYRSSYVNTVANETRWISVTQFEPAAARLAFPCFDEPGYKASFAITLGYHKKYTGLSNMPVNE-TRPHESIPDYVWTSFEESLPMSTYLVAYSLNDFSHKPSTLPNG---TLFRTWARPNAID--QCDYAAELGPKVLKYYEELFGIKFPLPK---VDQIAVPDFSAGAMENWGLVTFAESTLLYSP---EYSSQEAKQETANIVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLCVEDIHPQWRTLQLESMSNLLTIFRKDSLESSHPISRP---IEMTSQISESFDEISYQKGSSVIRMMHLFLGEEAFRTGLKSYLEKYTYKNAEQDNLWESLTQAAHKTGSLPKDYNIKTIMDSWTLQTGYPVINVTRDYTSRTAKLSQERYLLNTDVSRAHKG-CWWVPLSYTNQEEKDFNNTAPKEWMECTETGESVPKTIHDLPG-PDQWVIFNNQLSAPYKVNYDAQNWKLLIETLNSEDYHSIHVVNRAQLIDDVLYFAWTGEQDYEIALQVISYLERERE-LLPWKSAFDNLQFVSGILRQTPNFRFFKNFTRRLITPIYEHLNGINDTVASEEQ-QDKTILKAIVADWACSFEVSDCVTQALSFYRSWRSEANPDEVNPVPLGIRGVVYCTAIKHGCDEDWDFLWTRYQKANVATEKQIILDSLGCSQEVWVLQRYLERNFDGMGDIRKQDSTSVFQAIADSEVGFLLAKKYLMDNVDSISKFYHPQSESMSELLPPLSEQIFTQRDYDEFMNFMASSKDQ-LKDIEQTISQSLETMLINVQWKERNYERFTRAISKHF-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0KI00-1", "uniprot_id": "Q0KI00_DROME", "id": "Q0KI00-1", "name": "Aminopeptidase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MKWFLLFVAALGLGLATADSSADSIET---------------------------------------------------------TYNYYRLPTSLRP-------------------------------------QKYHLRILTLLENPED--LRFSGSVKILIE----ALENTKNVTLHSKNLTIDESQITLRQIGGE-GKKENC--VSSTAVNPSHDFYILNTCQELLAGNTY--ELYMPFAADLNRQLEGYYRSSYKDPVANLTKWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKYTAISNMPEKE-TKPHETLADYIWCEFQESVPMSTYLVAYSVNDFSHKPSTLPNS---ALFRTWARPNAID--QCDYAAQFGPKVLQYYEQFFGIKFPLPK---IDQIAVPDFSAGAMENWGLVTYREIALLYSA---AHSSLADKQRVASVVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLGVENINPEWRSMEQESLSNLLTIFRRDALESSHPISRP---IQMVSEISESFDQISYQKGSTVLRMMHLFLGEESFRSGLQAYLQKFSYKNAEQDNLWESLTQAAHKYRSLPKSYDIKSIMDSWTLQTGYPVINVTRDYAARTAKLNQERYLLNTQVARAYRGGCWWVPLSYTTQAVQDFNNTAPKAWMECGKNGESLPKTIQDLPG-PDQWVIFNTQLSTLYKVNYDAQNWKLLIETLTNGDFERIHVINRAQLIDDALYLAWTGEQDYEIAMRLIEYLQRERE-YLPWKSAFENLKRVGRIVRQTPDFEFFKRYMKKLILPIYEHLNGINDTFSAIPQ-QDQVLLKTMVVNWACQYQVGDCVPQALAYYRNWRAEANPDEKNPVPINVRSTVYCTSIKHGSDSDWEFLWTRYKKSNVAAEKRTILTALGCSREVWLLQRYLELTFDPKEAIRKQDSMWAFQAVAFNEVGFLLAKKYFMDNVDFIYKFYHPLTKDMSRLLSPLSEQVITLSDFNEFKDFVNNSRQS-LKGLEQAIQQTLEIMLTNVQWKERNYHQMSRSIQQLL-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P97449-1", "uniprot_id": "AMPN_MOUSE", "id": "P97449-1", "name": "Aminopeptidase N", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MAKGFYISKTLGILGILLGVAAVCTIIALSVVYAQEKNRNAENSA-------------------------TAPTLPGSTSATTATTTPAVDESKPWNQYRLPKTLIP-------------------------------------DSYRVILRPYLTPNNQGLYIFQGNSTVRFT----CNQTTDVIIIHSKKLNYTLKGNHRVVLRTLDGTPAPN--IDKTELVERTEYLVVHLQGSLVEGRQY--EMDSQFQGELADDLAGFYRSEYME--GDVKKVVATTQMQAADARKSFPCFDEPAMKAMFNITLIYPNNLIALSNMLPKE-SKPYPEDPSCTMTEFHSTPKMSTYLLAYIVSEFKNISSVSANG---VQIGIWARPSAIDEGQGDYALNVTGPILNFFAQHYNTSYPLPK---SDQIALPDFNAGAMENWGLVTYRESSLVFDS---QSSSISNKERVVTVIAHELAHQWFGNLVTVAWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSSPADEIKTPDQIMELFDSITYSKGASVIRMLSSFLTEDLFKKGLSSYLHTYQYSNTVYLDLWEHLQKAVNQQTAVQPPATVRTIMDRWILQMGFPVITVN----TNTGEISQKHFLLDSKSNVTRPSEFNYIWIAPIPFLKSG---QEDHYWLDVEKNQSAKFQTSS------NEWILLNINVTGYYLVNYDENNWKKLQNQLQT-DLSVIPVINRAQIIHDSFNLASAKMIPITLALDNTLFLVKEAE-YMPWQAALSSLNYFTLMFDRSEVYGPMKRYLKKQVTPLFFYFQNRTNNWVNRPPTLMEQYNEINAISTACSSGLKECRDLVVELYSQWMKNPN---NNTIHPNLRSTVYCNAIAFGGEEEWNFAWEQFRNATLVNEADKLRSALACSKDVWILNRYLSYTLNP-DYIRKQDTTSTIISIASNVAGHPLVWDFVRSNWKKLFENYGGGSFSFANLIQGVTRRFSSEFELQQLEQFKADNSATGFGTGTRALEQALEKTRANIDWVKENKDAVFKWFTENSS------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P15684-1", "uniprot_id": "AMPN_RAT", "id": "P15684-1", "name": "Aminopeptidase N", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MAKGFYISKTLGILGILLGVAAVCTIIALSVVYAQEKNRNAENSA-------------------------IAPTLPGSTSATTSTTNPAIDESKPWNQYRLPKTLIP-------------------------------------DSYQVTLRPYLTPNEQGLYIFKGSSTVRFT----CNETTNVIIIHSKKLNYTNKGNHRVALRALGDTPAPN--IDTTELVERTEYLVVHLQGSLVKGHQY--EMDSEFQGELADDLAGFYRSEYME--GGNKKVVATTQMQAADARKSFPCFDEPAMKASFNITLIHPNNLTALSNMLPKD-SRTLQEDPSWNVTEFHPTPKMSTYLLAYIVSEFKYVEAVSPNR---VQIRIWARPSAIDEGHGDYALQVTGPILNFFAQHYNTAYPLEK---SDQIALPDFNAGAMENWGLVTYRESALVFDP---QSSSISNKERVVTVIAHELAHQWFGNLVTVDWWNDLWLNEGFASYVEFLGADYAEPTWNLKDLIVLNDVYRVMAVDALASSHPLSSPANEVNTPAQISELFDSITYSKGASVLRMLSSFLTEDLFKKGLSSYLHTFQYSNTIYLDLWEHLQQAVDSQTAIKLPASVSTIMDRWILQMGFPVITVN----TSTGEIYQEHFLLDPTSKPTRPSDFNYLWIVPIPYLKNG---KEDHYWLETEKNQSAEFQTSS------NEWLLLNINVTGYYQVNYDENNWRKIQNQLQT-DLSVIPVINRAQIIHDSFNLASAGKLSITLPLSNTLFLASETE-YMPWEAALSSLNYFKLMFDRSEVYGPMKRYLKKQVTPLFAYFKIKTNNWLDRPPTLMEQYNEINAISTACSSGLEECRDLVVGLYSQWMNNSD---NNPIHPNLRSTVYCNAIAFGGEEEWNFAWEQFRKATLVNEADKLRSALACSNEVWILNRYLSYTLNP-DYIRKQDATSTIVSIANNVVGQTLVWDFVRSNWKKLFEDYGGGSFSFANLIQGVTRRFSSEFELQQLEQFKEDNSATGFGSGTRALEQALEKTKANIKWVKENKDVVLKWFTENS-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P15144-1", "uniprot_id": "AMPN_HUMAN", "id": "P15144-1", "name": "Aminopeptidase N", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MAKGFYISKSLGILGILLGVAAVCTIIALSVVYSQEKNKNANSSP-------------------------VASTTPSASATTNPASATTLDQSKAWNRYRLPNTLKP-------------------------------------DSYRVTLRPYLTPNDRGLYVFKGSSTVRFT----CKEATDVIIIHSKKLNYTLSQGHRVVLRGVGGSQPPD--IDKTELVEPTEYLVVHLKGSLVKDSQY--EMDSEFEGELADDLAGFYRSEYME--GNVRKVVATTQMQAADARKSFPCFDEPAMKAEFNITLIHPKDLTALSNMLPKGPSTPLPEDPNWNVTEFHTTPKMSTYLLAFIVSEFDYVEKQASNG---VLIRIWARPSAIAAGHGDYALNVTGPILNFFAGHYDTPYPLPK---SDQIGLPDFNAGAMENWGLVTYRENSLLFDP---LSSSSSNKERVVTVIAHELAHQWFGNLVTIEWWNDLWLNEGFASYVEYLGADYAEPTWNLKDLMVLNDVYRVMAVDALASSHPLSTPASEINTPAQISELFDAISYSKGASVLRMLSSFLSEDVFKQGLASYLHTFAYQNTIYLNLWDHLQEAVNNR-SIQLPTTVRDIMNRWTLQMGFPVITVD----TSTGTLSQEHFLLDPDSNVTRPSEFNYVWIVPITSIRDGR--QQQDYWLIDVRAQNDLFSTSG------NEWVLLNLNVTGYYRVNYDEENWRKIQTQLQR-DHSAIPVINRAQIINDAFNLASAHKVPVTLALNNTLFLIEERQ-YMPWEAALSSLSYFKLMFDRSEVYGPMKNYLKKQVTPLFIHFRNNTNNWREIPENLMDQYSEVNAISTACSNGVPECEEMVSGLFKQWMENPN---NNPIHPNLRSTVYCNAIAQGGEEEWDFAWEQFRNATLVNEADKLRAALACSKELWILNRYLSYTLNP-DLIRKQDATSTIISITNNVIGQGLVWDFVQSNWKKLFNDYGGGSFSFSNLIQAVTRRFSTEYELQQLEQFKKDNEETGFGSGTRALEQALEKTKANIKWVKENKEVVLQWFTENSK------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TCP8-1", "uniprot_id": "A0A8N7TCP8_DANRE", "id": "A0A8N7TCP8-1", "name": "Aminopeptidase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------MGKGYYISKHLATAAMILAAIALVTIIALSVVYNREKSKNT------------------------------AKLTNATTSAVPPTPKPSNE---PWDKYRLPDTLSP-------------------------------------QYYNITLWPRLVMDANGMYIFTGISDVMFT----CVKKTDLILIHSNKLNLTLFNGRHAKLTGMSGVTAPA--IKSTWLQTQTQYLVIQLKGKLNPGKSY--WLHTEFTGELADDLEGFYRSEYME--DGEKKIIAITQMQATYARKAFPCFDEPAMKAVFNIILIHDRGMTALSNSQEIRTEDVIIDEMPVTRTTFEPTARMSTYLVAFVVSDFSYINNEDKAG---VLVRIWARKKAIDDGQGDYALSITQPILEFFESYYNTSYPLSK---SDQVALPDFNSGAMENWGLVTYRETALLYDP---QTSANGNKQRIATVVSHELAHMWFGNLVTLKWWNDLWLNEGFASYVEYLGADHAEPTWNIKDQIILYDMQRAFAVDSLTSSHPLSRKEEEVNTPAEISEMFSTISYSKGAAVLKMLSEFLTEPVFAKGLSNYLKQFAFGSSVHSDLWDHLQKSLDQAPGMKLPRSVHEIMSRWILQMGFPVITID----TRTGNVSQKHFLVEKDAVVERNSEFNYEWFVPIKWMKKGQ--VQDQMWLLQKSAIHKPMKVSK------GEWVLANHNVSGYFRVNYDHGNWERLLSQLET-NHQTIPVVNRAQILDDAFNLARASIINITLALRTTKYLVRERE-YIPWEAALRSLNYFFQLFDRNEVYGALQAYLKKQVKPLFEHFGTISSNWTKVPNGHTDQFTQIIALSLACGTGVEGCREITKSWFKKWMQNPR---VNPIHPNLRSTVYCNAIAAGGADEWNFGWQMFQKATVAAEAVKLRAALACTKVPWLLNRYLEYSINP-EKIRKQDATSTIGYIASNVIGQPLAWNFVRANWDYFFKVYGTGSFTFSRLISDITSKFCTPFELSQLKRFQKDNAETGFGSGTQALQQAIERTTAKIKWLAENKEPVLQWFISESA------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KH77-1", "uniprot_id": "A0A0B4KH77_DROME", "id": "A0A0B4KH77-1", "name": "", "aln": "MEGGYVNEEDSDAIMGVESPAIISFTNPKLQIPLMASAIYAPTTITTNTTSTAGTPTSAKNASASASASASASLSSPAGPSAAGSASTSSAPAGGGPWQGLVAKLRNFKLDDTKNIRKRFHFDYISKDRFLGGQLKTKNGQKYVFNGPPSGVYVSKACLIIAAFITVLALLFTIAITYFVTRQGLNPKEVTPPSCITADHPDVNATPIQTAGWVSMNSPPPLQAATPTPMASPTPTNTPTVTTTLAMPASSEKPEIRMVDPKVGDIPVVEPAAGEVEDNTTKPINRPLKLYEGWRPLHYSLLIEPSVATSISNGSLTIEIERDVSKVTSWEPIVLDVHNVSISNVRVIRALADGASNASEEQDLDFDSDYGEDNATFVINLSKTLAVETQLRVLLSLDFVSQVTDTLQGIYKTSYTNPDTKNEEWMISTQFSPVDARRAFPCFDRPDMKANFSISIVRPMQFKMALSNMPKSGSRRFRRG--FIRDDFETTPKMPTYLVAFIVSNMVDSRLASQDSGLTPRVEIWTRPQFVG--MTHYAYKMVRKFLPYYEDFFGIKNKLPK---IDLVSVPDFGFAAMENWGLITFRDSALLVPEDLQLASSSEHMQVVAGIIAHELAHQWFGNLVTPKWWDDLWLKEGFACYMSYKALEHAHPEFQSMDTLTMLEFKESMEHDADNTSHAISFD---VRSTNDVRRIFDPISYSKGTILLRMLNSIVGDVAFRSATRDLLKKFAYGNMDRDDLWAMLTRHGHEQGTLPKDLSVKQIMDSWITQPGYPVVNVER--RGADLVLRQERYLLPSKNTADQSTWFIPITFETDELRKGDN---IPTHWMRSEDEEELIVGNVFAHSSNSDNVIYLNLNRQGYYRVNYDMTSWLALKKNFST-----LPRITRAQLLDDALHLSQAEYLTYDIPLTFLMELFDAVDDELLWIAAKPGLNYLIYNLKREPAYETFRAFMKFIVRPAFDHYG----LHEPDNESHLQLKHRALVAYFACKFNYDRCTQKAQMKFREWMRDPK---NNPIKPNLKSVIYCTSLAEGSSPEWYFAYKQYKTTTSASEKEEILTSLGCTTKPWLLSKYLNMTINPTSGILKQDGALAFRAVASNAIGHEIAFDFLQGNIKEIVEYYGDGFSTLSEMIKSLTIYMNKDYHKHQLLDLAATCRKLGLHAVESAIELALEQVNNNIYWRSHSYHSLKNFLEGIVSEFQINIF-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VD85-1", "uniprot_id": "Q9VD85_DROME", "id": "Q9VD85-1", "name": "Aminopeptidase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MSSSIFRAFWLLCSLLICVT--------------------------------------------------------------------NAADYRLEGSVVP-------------------------------------SHYNLTIG--VLRNSVEPTIFDGEVSITLR-------VVGTLEVQQIILHADTLDITECWLLDAAGAQVEAIDISRLIYEAATQQVRVPLTEAAQPGKNY--TLGFKYTGHIRTDMAGFFSASYVERDTNVTRWLALTQMQRINARLVLPCFDEPALKAQFQLQIVRPNGYQSIANTKLKETKALSQDR---FVDHFKETPVMSTYLLAFMVANYSARGNE-------SEFAVLTRPEFYDN--TEFSYHVGQQVVSAYGELFQSPYAELGNDVLQYASSPRFPHNGMENWGLIIYSDDVLIQEPG--YSDDWSDKEFAIRIIAHETSHMWFGDSVTFSWWSYFWLNEAFARYYEYFMAHQLYPDYHLDEQFVVRQMQLIFGTDAQNGTQPMTSPESEIQTPSQIAYKFSGIAYAKGACIVRMWRNLMGAENFDTAIRSYLQQYHLTNTVPYNLFYHLFEHWPKN----QDVDLVDFLTDYTEQVGYPMIIVKALQGNKVVTVEQSRFLLNKD-DGSNATLKYTVPITFTTNLERDFYNLTPYKYLHKTVNVLWLDFTSP------IDWILFNLRQSNYQRVFYDDTLREGLLLAISATNHSGIPVENRAQIIDDLFNFAQAQYVDYADVFRFLEYLAKEVE-YVPWYAVYENLNTVAKRLTP-EQLPDFRIYLSSITAAVFEKLG----VGWNAQDTPLDVANRNKLIKWLCRYQASNCRPKVNVQFVTGHEVPS--------PDYRETFYCAASG-ADYNSYTMLWGQYYLENRTSEKNMLWAAISCTRD--YETHYHKMIISGTESVE-QKKIGIARMYEENPDLVQAIFEMITENIMELAYNFQSWS-DTAEVINDMAEYFTTREQQQLLKEFYYS-NHQFFGESEELLSKSLVTVEKNLNWAETHLEGLVKYLADRNGSSCLGATSLVVVLLLAVGSMLAWP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : : * . : : * : : : :. : : : : ..: : * : :.* : . : **:. ** :****.* ** * : : . *. : *.***:*: : : . :* . .:: . .: : : : . * * .******: : : *: . : :::** :* ***: ** ** :**:*.** * . * :. : : :. : *: ::.:: :. :: *. *:* **: :::* :: * . *. : . :*: * . . : :: : * *:*:: : : *.::*: : . :: : : * . * ** : : : .***::.* : :: : : * : : * :. .*. . . :: : . : . . * * . : . . : ..** : . .: : : : . . * : ::.*: :* . :. : *. . . . * : : :.:: :: . . . : : : :. :: :: * . . . : ", "identical_positions": 86, "similar_positions": 203, "identity": "6.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-597", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54800-1", "uniprot_id": "CADH8_RAT", "id": "O54800-1", "name": "Cadherin-8", "aln": "MPERLAETLLDLWTPLIILWITLPSFVYMAPMN-QAHVLTTGSPLELS-RQSEEMRILNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSGDGAGTIFQINDITGDIHAIKRLDREEKAEYTLTAQAVDWETNKPLEPPSEFIIKVQDINDNAPEFLNGPYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQPYFSIEPETAIIKTALPNMDREAKEEYLVVIQAKDMGGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDVVLGTAIGRVKANDQDIGENAQSSYDIIDGDGTALFEITSDAQAQDGVIRLRKPLDFETKKSYTLKVEAANIHIDPRFSGRGPFKDTATVKIVVEDADEPPVFSSPTYLLEVHENAALNSVIGQVTARDPDITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDRELSVWHNISIIATEIRNHSQISRVPVAIKVLDVNDNAPEFASEYEAFLCENGKPGQVIQTVSAMDKDDPKNGHFFLYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLLPIVISDSGNPPLSSTSTLTIRVCGCSNDGVVQSCNVEPYVLPIGLSMGALIAILACIILLLVIVVLFVTLRRHKNEPLIIKDDEDVRENIIRYDDEGGGEEDTEAFDIATLQNPDGINGFLPRKDIKPDLQFMPRQGLAPVPNGVDVDEFINVRLHEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESTTSDSDQNFDYLSDWGPRFKRLGELYSVGESDKET", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97291-1", "uniprot_id": "CADH8_MOUSE", "id": "P97291-1", "name": "Cadherin-8", "aln": "MPERLAETLMDLWTPLIILWITLPSCVYTAPMN-QAHVLTTGSPLELS-RQSEDMRILSRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSGDGAGTIFQINDITGDIHAIKRLDREEKAEYTLTAQAVDFETNKPLEPPSEFIIKVQDINDNAPEFLNGPYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQPYFSIEPETAIIKTALPNMDREAKEEYLVVIQAKDMGGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDVVLGTAIGRVKANDQDIGENAQSSYDIIDGDGTALFEITSDAQAQDGVIRLRKPLDFETKKSYTLKVEAANIHIDPRFSSRGPFKDTATVKIVVEDADEPPVFSSPTYLLEVHENAALNSVIGQVTARDPDITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDRELSVWHNITIIATEIRNHSQISRVPVAIKVLDVNDNAPEFASEYEAFLCENGKPGQVIQTVSAMDKDDPKNGHFFLYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLLPIVISDSGNPPLSSTSTLTIRVCGCSNDGVVQSCNVEAYVLPIGLSMGALIAILACIILLLVIVVLFVTLRRHKNEPLIIKDDEDVRENIIRYDDEGGGEEDTEAFDIATLQNPDGINGFLPRKDIKPDLQFMPRQGLAPVPNGVDVDEFINVRLHEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESTTSDSDQNFDYLSDWGPRFKRLGELYSVGESDKET", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55286-1", "uniprot_id": "CADH8_HUMAN", "id": "P55286-1", "name": "Cadherin-8", "aln": "MPERLAEMLLDLWTPLIILWITLPPCIYMAPMN-QSQVLMSGSPLELN-SLGEEQRILNRSKRGWVWNQMFVLEEFSGPEPILVGRLHTDLDPGSKKIKYILSGDGAGTIFQINDVTGDIHAIKRLDREEKAEYTLTAQAVDWETSKPLEPPSEFIIKVQDINDNAPEFLNGPYHATVPEMSILGTSVTNVTATDADDPVYGNSAKLVYSILEGQPYFSIEPETAIIKTALPNMDREAKEEYLVVIQAKDMGGHSGGLSGTTTLTVTLTDVNDNPPKFAQSLYHFSVPEDVVLGTAIGRVKANDQDIGENAQSSYDIIDGDGTALFEITSDAQAQDGIIRLRKPLDFETKKSYTLKVEAANVHIDPRFSGRGPFKDTATVKIVVEDADEPPVFSSPTYLLEVHENAALNSVIGQVTARDPDITSSPIRFSIDRHTDLERQFNINADDGKITLATPLDRELSVWHNITIIATEIRNHSQISRVPVAIKVLDVNDNAPEFASEYEAFLCENGKPGQVIQTVSAMDKDDPKNGHYFLYSLLPEMVNNPNFTIKKNEDNSLSILAKHNGFNRQKQEVYLLPIIISDSGNPPLSSTSTLTIRVCGCSNDGVVQSCNVEAYVLPIGLSMGALIAILACIILLLVIVVLFVTLRRHKNEPLIIKDDEDVRENIIRYDDEGGGEEDTEAFDIATLQNPDGINGFLPRKDIKPDLQFMPRQGLAPVPNGVDVDEFINVRLHEADNDPTAPPYDSIQIYGYEGRGSVAGSLSSLESTTSDSDQNFDYLSDWGPRFKRLGELYSVGESDKET", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z1S0-1", "uniprot_id": "A0A8M6Z1S0_DANRE", "id": "A0A8M6Z1S0-1", "name": "", "aln": "MPKRGEEMQRDLWTSLLLVWITCVPYSSMAPLNNQSQSLQTASAMIPRNRPSEGQRILSRAKRGWVWNQMFVLEEFSGPDPILVGRLHTDLDVGSKNIKYVLAGEGAGTIFAINERTGDIHAMKRLDREEKAEYTLTAQVIDRDSNQPLEPPSEFIIKVQDINDNPPQFIEGPYKGSVPEMSQVGASVTRVTASDADDPVYGNSAKLVYSILEGQPYFSIDQTTAIIRVALAGMDREMREEYLVVIQAKDMGGHMGGLSGTTTVTVTLTDINDNPPKFTKGSYEFHIPEDLGIGKPGGRVKANDRDIGENAKSTYTIIGGDERDVFEIVTDAQTQEGILRLKKPLDFESKEFYNLTVVATNIRADS-ITG-GPYMDQATIKVVVQDSDEPPVFTKPSYLFDVHENAAINTVIGAVAARDQDATHSQVRYFIDRHTDLERQFNINVDDGKITLAKPLDRETDMWHNITVTATEVHNHSQISRAIVAIKVLDINDNAPEFATEYEAFLCENGKPGQVIQTISAVDKDNPSQGHTFHYRL--EMLNNPNFTIKNNLDNSISVLAKHDSFRRQKQETYLLPIVVTDDGEPPMSSTNTLTIRVCGCSREGIVQSCNVEAFVLPIGLSMGALIAILACIILLLVIVVLFVTLRRHKNEPLIIKDDEDVRENIIRYDDEGGGEEDTEAFDIATLQNPDGINGYLPRKDIKPDLQFMPRQGQHSGPNGVDVDEFINVRLHEADNDPTAPPYDSIQIYGYEGRGSIAGSLSSLETASSDSDQNYDYLREWGPRFRRLGELYSVGESDKET", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* * ****.*:::*** . **:* *:: * :.*.: .* ***.*:******************:************ ***:***:*:*:****** **: ******:****************.:* ::.:******************.*:*::***:.:***** :*:***.***:**************************: ****:.**..**** :*************** ********:******:*******::. *.* :***: :*.. *******:******:*:* **.** :***.:***:*:*::**:******:*: *.*.* *:*:: *. ::. **: * **:*:**:*:******:.*:**::******:*:*** *:*** * * * :*: **************.********.***** .:****:: ***::*******. *******:********:******************:**:***:*.:** * * * **:********:* ***:*:****:.*.*****.*****:::*.*:**:***.**********.:*:*******.:********************************************************************************:***************** . ***************************************:********:::******:*** :*****:***************", "identical_positions": 596, "similar_positions": 140, "identity": "74.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-599", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RJI4-1", "uniprot_id": "PKDCC_MOUSE", "id": "Q5RJI4-1", "name": "Extracellular tyrosine-protein kinase PKDCC", "aln": "----MRRRRAAVAAGFCASFLLGSVLNVLFAPGSEPPRPGQSPGSSAAPGPGRRGGRG------ELARQIRERYEEVQRYSRGG----PGPGAGRPE----RRRLMDLAPGGPGLQRPRPPRVRSPPDGAPGWPPAPGPGSPGPGPRLGCAALRNVSGAQYVGSGYTKAVYRVRLPGGAAVALKAVDFSGHDLGSCVREFGARRGCYRLAAHKLLKEMVLLERLRHPNVLQLYGYCYQDSEGIPDTLTTITELGAPVEMIQLLQTSWEDRFRICLSLGRLLHHLAHSPLGSVTLLDFRPRQFVLVNGELKVTDLDDARVEETPCTSSADCTLEFPARNFSLPCSAQGWCEGMNEKRNLYNAYRFFFTYLLPHSAPPSLRPLLDSIVNATGELAWGVDETLAQLETALHLFRSGQYLQNS-TSSRAEYQRIPDS-AITQEDYRCWPSYHHGGCLLSVFNLAEAIDVCESHAQCRAFVVTNQTTWTGRKLVFFKTGWNQVVPDAGKTTY---VKAPG---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M6Z1S2-1", "uniprot_id": "A0A8M6Z1S2_DANRE", "id": "A0A8M6Z1S2-1", "name": "Extracellular tyrosine-protein kinase PKDCC", "aln": "MSSKTRPLGVTAAHTYYTKLQYARTQSARVKYEQRRCRTLTVHKKDLPLKLAMTFQRSPFCAFVLLALLFLSLTLIVKKWHFGLQENEPFGDAARPDGSAPQRDTLRQQLQERQQELVLLDITFEDIQQQEGFNGKISLDNP-TAADIGCEELGGVKAVDFLGSGYTKTVLKAALPNGLFVALKSVNHQGTDMRLCLDVFQDSQGCLELVSFKLRKEIVLLQKLQHPNIVELKGQC-QDSILVGG-ITAVLEQGMPLQMIQLLQSPWEERFRVCLGLVRLLQYLSVSPLGSVALLDFQPRQFVMVSGELKLTDLDDASIHEPVCQEDSDCLLQFPLRNFTLRCSPAQTCKGLNEMRNLYNAYRYFFTYLLPHQAPPLLKPLIHHIMNATGDLKQSINETLIAFEKILHIYKSGLHLENLPTSITKDYAVLKGMRSVVNVEYRCWPSYRQQGCVLSVHSVREAAFICNSHTHCTSFSISSQTTWTGRLLASFRSGFSHLVPDVNSAVYMRRVKASGAVL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .:.* : :.: . . .. . .. *. .. . . *. ** : . *::: * * .*.**: :* : : . . : *: . ..* ... :** * .*...:::******:* :. **.* ****:*:..* *: *: * :** .*.:.** **:***::*:***:::* * * *** : . :*:: * * *::******:.**:***:**.* ***::*: ******:****:*****:*.****:****** :.*. * ..:** *:** ***:* **. *:*:** ********:********.*** *:**:. *:****:* .::*** :*. **:::** :*:* ** :* : . ::.: :*******:: **:***..: ** :*:**::* :* ::.******* *. *::*:.::***...:.* ***.* ", "identical_positions": 201, "similar_positions": 154, "identity": "38.8%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-600", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A8MV65-1", "uniprot_id": "VGLL3_HUMAN", "id": "A8MV65-1", "name": "Transcription cofactor vestigial-like protein 3", "aln": "MSCAEVMYHPQPYGASQYLPNPMAATTCPTAYY---QPAPQPGQQKKLAVFSKMQDSLEVT-----------LPSKQEEEDEEEE---EEEKD------QPAEMEYLNSRCVLFTYFQGDIGSVVDEHFSRALGQAITLHPESAISKSKMGLTPLWRDSSALS-SQRNSFPTSFWTSSYQPPPAPCLGGVHPDFQVTGPPGTFSAADPSPWPGHNLHQTGPAPPPAVSESWPYPLTSQVSPSYSHMHDVYMRHH--HPHAHMHHRHRHHHHHHHPPAGSALDPSYGPLLMPSVHAARIPAPQCDITKTEPTTVTSATSAWAGAFHGTVDIVPSVGFDTGLQHQDKSKESPWY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P85442-1", "uniprot_id": "VGLL3_MOUSE", "id": "P85442-1", "name": "Transcription cofactor vestigial-like protein 3", "aln": "MSCAEVMYHPQPYGAPQYLPNPVAAATCPTACY---HPAPQPGQQKKLAVYSKMQDSLEVT-----------LPSKQEEEEEEEEDEEEEEKD------QPAEMEYLNSRCVLFTYFQGDIGSVVDEHFSRALGQANTLHPESAISKSKMGLTPLWRDSSALS-SQRSNFPTSFWTSSYQPPPAPCLGGVHPDFQVTAPHGTFTTADPNSWPGHGLHQTGPAPPPTASESWHYPLASQVSPSYSHMHDMYLRHH--HPHAHVHHRH---HHHHHPTAGSALDPAYGHLLMPSVRAARIPAPQCDITKTDLTTVTTATSAWAGAFHGTVDIVPSVGFDTGLQHQDKSKESTWY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FDS8-1", "uniprot_id": "E7FDS8_DANRE", "id": "E7FDS8-1", "name": "", "aln": "MSCLDVMYHHQSYGAHHYLPSTSAAAAAYKAAYLHHHHQQQQQQQKKFSVFSRMQDSEEFPSHCGQNKQPGALKSRSEPELLPEEEQSSGEEDRCKDTLQPADAEYLSARCVVFTYFRGDIGDVVDEHFSRALSQNSAFSNDTKASRLNPGGP--WKEGNSHSEGQTSSLPSSLWGSGYPSQSSPCVPSSHHDFP---PSAAFHPADNGIWSSHSLAP----PPSALTDSWHYSLGPQSGAGYPHVHEMYPHMHPRHPHPHAHHVL---HHAHSP----ALDPRFNPLLLPGVRASCSPTSCTDTIKTELEPSSIPTPSWPASFHGSVDIY-----DTALE-QDKAKASVWF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** :**** *.*** :***.. **::. .* * : * ****::*:*:**** *.. * *:.* * ** . *:* ***: ***.:***:****:****.**********.* :: :: *: : * . *::..: * .* ..:*:*:* *.* . .:**: . * ** * .:* .** . *..*.* **.: ::** *.* .* ...*.*:*::* : * ***.* ** ** * * **** :. **:*.*:*: *:. * **: . : .*.:*..:***:*** **.*: ***:* * *:", "identical_positions": 140, "similar_positions": 95, "identity": "39.77%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-601", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y2L5-1", "uniprot_id": "TPPC8_HUMAN", "id": "Q9Y2L5-1", "name": "Trafficking protein particle complex subunit 8", "aln": "MAQCVQSVQELIPDSFVPCVAALCSDEAERLTRLNHLSFAELLKPFSRLTSEVHMRDPNNQLHVIKNLKIAVSNIVTQPPQPGAIRKLLNDVVSGSQPAEGLVANVITAGDYDLNIS----------------------------ATTPWFESYRETFLQSMPALDHEFLNHYLACMLVASSSEAEPVEQFSKLSQEQHRIQHNSDYSYPKWFIPNTLKYYVLLHDVSAGDEQRAESIYEEMKQKYGTQGCYLLKINSRTSNRASDEQIPDPWSQYLQKNSIQNQESYEDGPCTITSNKNSDNNLLSLDGLDNEVK-DGLPNNFRAHPLQLEQSSDPSNSIDGPDHLRSASSLHETKKG-----NTGIIHGACLTLTDHDRIRQFIQEFTFRGLLPHIEKTIRQLNDQLISRKGLSRSLFSATKKWFSGSKVPEKSINDLKNTSGLLYPPEAPELQIRKMADLCFLVQHYDLAYSCYHTAKKDFLNDQAMLYAAGALEMAAVSAFLQPGAPRPYPAHYMDTAIQTYRDICKNMVLAERCVLLSAELLKSQSKYSEAAALLIRLTSEDSDLRSALLLEQAAHCFINMKSPMVRKYAFHMILAGHRFSKAGQKKHALRCYCQAMQVYKGKGWSLAEDHINFTIGRQSYTLRQLDNAVSAFRHILINESKQSAAQQGAFLREYLYVYKNVSQLSPDGPLPQLPLPYINSSATRVFFGHDRRPADGEKQAATHVSLDQEYDSESSQQWRELEEQVVSVVNKGVIPSNFHPTQYCLNSYSDNSRFPLAVVEEPITVEVAFRNPLKVLLLLTDLSLLWKFHPKDFSGKDNEEVKQLVTSEP------------EMIGAEVISEFLINGEESKVARLKLFPHHIGELHILGVVYNLGTIQGSMTVDGIGALPGCHTGKYSLSMSVRGKQDLEIQGPRLNNTKEEKTSVKYGPDRRLDPIITEEMPLLEVFFIHFPTGLLCGEIRKAYVEFVNVSKCPLTGLKVVSKRPEFFTFGGNTAVLTPLSPSASENCSAYKTVVTDATSVCTALISSASSVDFGIGTGSQPEVIPVPLPDTVLLPGASVQLPMWLRGPDEEGVHEINFLFYYESVKKQPKIRHRILRHTAIICTSRSLNVRATVCRSNSLE----------NEEGRGGNMLVFVDVENTNTSEAGVKEFHIVQVSSSSKHWKLQKSVNLSENKDTKLASREKGKFCFKAIRCEKEEAATQSSEKYTFADIIFGNEQIISSASPCADFFYRS-LSSELKKPQAHLPVHTEKQ---------STEDAVRLIQKCSEVDLNIVILWKAYVVEDSKQLILEGQHHVILRTIGKEAFSYPQKQEPPEMELLKFFRPENITVSSRPSVEQLSSLIKTSLHYPESFNHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALEIHGSFTWLGQTQYKLQLKSQEIHSLQLKACFVHTGVYNLGTPRVFAKLSDQVTVFETSQQNSMPALIIISNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A286YCX6-1", "uniprot_id": "A0A286YCX6_MOUSE", "id": "A0A286YCX6-1", "name": "", "aln": "MAQCVQSVQELIPDSFVPCVAALCSDEAERLTRLNHLSFSELLKPFSRLTSEVHMRDPNNQLHIIKNLKIAVSNIVTQPPQPGAIGKLLNDVVSGSQPAEGLVANVITAGDYDLNIS----------------------------ATTPWFESYRETFLQSMPASDHEFLNHYLACMLVASSGEAEPMEQFSKLSQEQHRIQHNNDYSYPKWFIPNTLKYYVLLHDVTSGDEQRAESIYEEMKQKYGTQGCYLLKINSRAPNRASDEQIPDPWSQYLQKNSIQNQESYEDGPCTMTSSKNSDSNLLSLDGLDNEVKVDGLPNNFRIHPLQIDQCGDPPNNTDGS-ESKSASSVHETKKA-----STAVIRGACLTLTDHDRIRQFIQEFTFRGLLPHIEKTIRQLNDQLISRKGLSRSLFSATKKWFSGSKVPEKSINELKNTSGLLYPPEAPELQIRKMADLCFLVQHYDLAYSCYHTAKKDFLNDQAMLYAAGALEMAAVSAFLQPGAPRPYPAHYMDTAIQTYRDICKNMVLAERCVLLSAEILKSQSKYSEAAALLIRLTSEDSDLRSALLLEQAAHCFINMKSPMVRKYAFHMILAGHRFSKAGQKKHALRCYCQAMQVYKGKGWSLAEDHINFTIGRQSYTLRQLDNAVSAFRHILINESKQSAAQQGAFLREYLYVYKNVNQLSPDGPLPQLPLPYINSSATRVFFGHDRRPADGEKQAATHISLDQEYDSESSQQWRELEEHVVAVANKGVIPSSFYPTQYCLNSYSDNSRFPLAVVEEPITVEVAFRNPLKVPLLLSDLSLLWKFQPKDASGKDIEKVKERVTGEP------------EMIGTEVISEFLINSEESKVARLKLFPHHIGELHILGVVYNLGTIQGSGTVDGIGALPGCHTGKHSLSMSVRGRQDLEIQGPRLNNTKEEKTSVKYGPDRRLDPIVTEEMPLLEVFFIHFPTGLLCGEIRKAYVEFVNVSKCPLTGLKVVSKRPEFFTFGGNTAALTPLSPSTSENCSAYKTVVTASPSLGTALVSTASSMDFGTGTGQQLEAIPVPLPDSVLLPGASIQLPMWLRGPDEEGVHEINFLFYYESVKKQPKKRHRILRHTAVICTSRSLNVRATVCRSNSLE----------DEEGRGGNMLVFVDVENTNTSEAGVKEFHMVQVSSSSKHWQLHKSVNISENKDAKLASREKGKFCFKAVRCKQKEGGIQSSEKYTFADIIFGNEQIISSASPCADFFYRS-LSSELKKTQDQLSAYPEKHRE-------ATEGAVRLVEKCSEVDLSIVILWKAYVVEDNKQLILEGQHHVVVRTVGKEAFSHSQKEEPPEMELLKFFRPENTTVSTRPSVEQLSNLIKTSLHYPESFHHPFHQKSLCLVPVTLLLSNCSKADVDVIVDLRHKTTSPEALETHGSFTWLGQTQYKLQLKSQEMHSLQLKACFVHTGVYNLGTPRVFAKLSDHVTVFETSQQNSMPALIIINNA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AA58BSJ9-1", "uniprot_id": "A0AA58BSJ9_DANRE", "id": "A0AA58BSJ9-1", "name": "", "aln": "MAQCVQSVQEFIQDSFVPMVAVLCSEDAERVTRKNNLSFPELLRPFCRLTSEGHLRDPNNQVVVVKGLRISVTGINTRPPQTPELQRVLSQAVSICQPPEGSPANVITAGDYDLNISDRTVKASVPWYSDWKETLTQLSSSKYYTATTPWFETYRENFLQSMPASEHEFLSHYLACMLVVSSNEAVPTEQFLKLSQEQHRIQHSGDYTHPKWFIPNTLKYYVLLHDISDGDEQRADSVYEDMKQRYGTQGCYLLKINSRSGSTGADEQMPDPWSQYLHKTSIHNPELYEESAVNNATENNIS---AEEDGLDPAVR-DGVSD---THPLQLDSPSD--ALIDESQAVNSANMTKALKQASVSSNSSPTPRGTCLTLNDHDHIRQFIQEFTFRGLLPHIEKNIRQLNDQLVSRKGLSRSLFSATKKLFGGGKVPEKSIAELKNTAGLLYPSEAPELQIRKMADLCFLVQHYELAYNCYHTAKKDFLSDQAMLYAAGALEMAAVAAFLQSGAPRPYPAHYMDTAIQTYRDVCKNMLLAERCCLLSAEILKSQAKYSDAATLLIKMTSEDSDLRSALLLEQAAHCFINMRSPMVRKFAFHMILAGHRFSKAGQKRHALRCYCQALQVYKGKGWTLAEDHINFTIGRQSFTLRQPENAVAAFRHILINDSKQSAVQQAAFLREYLYVYKSMSQVSGESSLPQLPLPCLHSSQTRVFFGHERRLAEGEKQAATHVSLDQEFDRDSSQLWKELEERVVAAANRGSVPNTFQPSQCCLNSQTDNLRYPLAVVEEPIIVEVVFRNPLKVPLALSALSLLWKFTVKDFSGPQDSTSGETISNEKEAVALKETTALGDIIDTQVIPEFTISPEETKVARLKLLPRKTGELHVLGVVYNLG----------TGEVGNSEGSLASDVMCVRGQQNLEIQGPRLNVTKEEKTSVKYGPDRRLDPIITPAMPLLEVFFINFPTGLLCGEIRKAWVEFVNVSGVPLTGLRVASTHPEFFTFGSATSDLTPVTPTAAEHCSAYKTVATAPSQASVSLVSPAA---FGVSSSDRPMVAEIPLSRGLLGPGDALQIPLWLRGPDREGVHEINFLFYYESTEKAAKLSHRVLRHTAFICASRSLSIRATASQSNTLYSREREKPEAGDGEEKNTSMLVFVDVENVNTSEAGVREFHIVQVSSSSRQWRLHKCINPVGDRDTKLASRERGKLCFKATRCKTEEATSDAAGKYTFADLNLGSEQIVSSTTPCADFFFRQGLPSEPRRGVVSAGGVSQMRRQSLTPQSGIDDDVTSIVRKCSEVELDIIVLWKAYVVEDNKQLILEGQLHVALQTIGKEACSLSQKEETQEMVLLK-FKPDLPPPVSKPSLEQLSHLIKTCLHYPESYDHPFPQKRLCMVPVTLMLSNCSLAQVDVIIDLRHKTTSPESLEVHGSFSWLGQTQYKLQLQAQEVHRLSLKACFFQAGVYNLGTPRVFAKLAQTSAMCETSQQSAMPALIIINSV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********:* ***** **.***::***:** *:***.***:**.***** *:******: ::*.*:*:*:.* *:***. : ::*.:.** .**.** ************** *******:***.******* :****.********.**.** * *** ***********..**::*****************:: ******:*:**:***:**************: . .:***:********:*.**:* * **:.. . ::.:* . . **** *: **:.: ****::. .* * . .**. : *:. .: :*:****.***:*******************.********:*************** *.*.******* :****:*****.********************:***.**********.****************:****.********************:****:***** *****:****:***:**:***::***********************:******:*****************:*********:********:**************:**** :***:********:*****.**.***********.:.*:* :..******* ::** *******:** *:********:*****:* :*** *:****:**:..*:* :*..* *:* **** :** *:********* ***.******* * *: ******* ** ** : . : ::.* ::*.::**.** *. **:*******:*:: ****:******** * : ... . * *.***:*:********* *******************:* *********:*************:******* *****:*.*.:*******. *: ***::*:::*:*******.* ... .:*:*.*: ** .:..: . :**. :* ** ::*:*:******.**************.:* .* **:*****.**:****.:***..:**:* : * :. .*********.*******:***:*******::*:*:*.:* ::*:******:**:**** **: :*. ::: ******: :*.***:**::******:*. *.** :: .: : :... ::.*****:*.*::*********.******** ** ::*:**** * .**:*. ** *** *:*: . ::**:**** ****.******:.*** ** **:*****:***** *:****:**********:** ****:***********::**:* *.*****.::**************:: :: *****.:*******...", "identical_positions": 958, "similar_positions": 304, "identity": "63.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-602", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R283-1", "uniprot_id": "TRPC2_RAT", "id": "Q9R283-1", "name": "Short transient receptor potential channel 2", "aln": "MLMSLTDSKEGKNRSGVRMFKDDDFLIPASGESWDRLRLTCSQPFTRHQSFGLAFLRVRSSLDSLSDPVKDPSSPGSSGLNQNSSDKLESDPSPWLTNPSIRRTFFPDPQTSTKEISALKGMLKQLQPGPLGRAARMVLSAAHKAPPASVVSPNNSHGEPDSSHPERAEPRAEEPNRKNNASRGKRRKVQEQRRPLSSSSSQPNRRATGRTKQRQQRPQAKSDGSGVQATGQCPICTGSFSIEALPRHAATCGESSPPQPASPTSLSSSESVLRCLHVALTPVPLIPKP--NWTEIVNKKLKFPPTLLRAIQEGQLGLVQQLLESGSDPSGAGPGGPLRNVEESEDRSWREALNLAIRLGHEVITDVLLANVKFDFRQIHEALLVAVDTNQPAVVRRLLARLEREKGRKVDTKSFSLAFFDSSIDGSRFAPGVTPLTLACQKDLYEIAQLLMDQGHTIARPHPVSCACLECSNARRYDLLKFSLSRINTYRGIASRAHLSLASEDAMLAAFQLSRELRRLARKEPEFKPQYIALESLCQDYGFELLGMCRNQSEVTAVLNDLGEDSETEPEAEGLGQAFEEGIPNLARLRLAVNYNQKQFVAHPICQQVLSSIWCGNLAGWRGSTTIWKLFVAFLIFLTMPFLCIGYWLAPKSRLGRLLKIPVLKFLLHSASYLWFLIFLLGESLVMETQLSTFKGRSQSVWETSLHMIWVTGFLWFECKEVWIEGLRSYLLDWWNFLDVVILSLYLASFALRLLLAGLAYMHCRDASDSSTCRYFTTAERSEWRTEDPQFLAEVLFAVTSMLSFTRLAYILPAHESLGTLQISIGKMIDDMIRFMFILMIILTAFLCGLNNIYVPYQETEKLGNFNETFQFLFWTMFGMEEHSVVDMPQFLVPEFVGRAMYGIFTIVMVIVLLNMLIAMITNSFQKIEDDADVEWKFARSKLYLSYFREGLTLPVPFNILPSPKAAFYLLRRIFRFICCGSSCCKAKKSDYPPIPTFTNPGARAG-PGEGE-HVSYRLRVIKALVQRYIETARREFEETRRKDLGNRLTELTKTVSRLQSEVASVQKTVAAGGALRPPDGASILSRYITRVRNSFQNLGPPAPDTPAELTMPGIVETEVSLEDSLDATGEAGTPASGESSSSSSAHVLVHREQEAEGAGDLPLGEDLETKGES-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9R244-1", "uniprot_id": "TRPC2_MOUSE", "id": "Q9R244-1", "name": "Short transient receptor potential channel 2", "aln": "MLMSRTDSKSGKNRSGVRMFKDGDFLTPASGESWDRLRLTCSQPFTRHQSFGLAFLRVRSSLGSLADPVVDPSAPGSSGLNQNSTDVLESDPRPWLTNPSIRRTFFPDPQTSTKEISELKGMLKQLQPGPLGRAARMVLSAARKAPPASVVSPNNSHGEPGPSRAESAEPRAEEPNRKTAVGRRKRRKVQEPRRSLSNSSSQPNRR-TGRTRQRQHRPQTKSDDGGVQAAGQCPICAGFFSIETLPQHAATCGESPPPQPASPASLSSSESVLRRHHVALTPVPLVPKPQPNWTEIVNKKLKFPPTLLRAIQEGQLGLVQQLLESSSDASGAGPGGPLRNVEESEDRSWREALNLAIRLGHEVITDVLLANVKFDFRQIHEALLVAVDTNQPAVVRRLLARLEREKGRKVDTKSFSLAFFDSSIDGSRFAPGVTPLTLACQKDLYEIAQLLMDQGHTIARPHPVSCACLECSNARRYDLLKFSLSRINTYRGIASRAHLSLASEDAMLAAFQLSRELRRLARKEPEFKPQYIALESLCQDYGFELLGMCRNQSEVTAVLNDLGEDSETEPEAEGLGQAFEEGIPNLARLRLAVNYNQKQFVAHPICQQVLSSIWCGNLAGWRGSTTIWKLFVAFLIFLTMPFLCIGYWLAPKSQLGRLLKIPVLKFLLHSASYLWFLIFLLGESLVMETQLSTFKGRSQSVWETSLHMIWVTGFLWFECKEVWIEGLRSYLLDWWNFLDVVILSLYLASFALRLLLAGLAYMHCRDASDSTTCRYFTTAERSEWRTEDPQFLAEVLFAVTSMLSFTRLAYILPAHESLGTLQISIGKMIDDMIRFMFILMIILTAFLCGLNNIYVPYQESEKLGNFNETFQFLFWTMFGMEEHTVVDMPQFLVPEFVGRAMYGIFTIVMVIVLLNMLIAMITNSFQKIEDDADVEWKFARSKLYLSYFREGLTLPVPFNILPSPKAAFYLVRRIFRFLCCGSSCCKAKKSDYPPIGTFTNPGARAGSAGEGE-RVSYRLRVIKALVQRYIETARREFEETRRKDLGNRLTELTKTVSRLQSEVASVQKNLAAGGAPRPPDGASILSRYITRVRNSFQNLGPPTSDTPAELTMPGIVETEVSLGDGLDGTGEAGAPAPGEPGSSSSAHVLVHREQEAEGSGDLLLEGDLETKGES-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M6Z1M8-1", "uniprot_id": "A0A8M6Z1M8_DANRE", "id": "A0A8M6Z1M8-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MENLTSD----------------------NWREIVNKKLHFPPELILAIQEGNMAWVDSLLSLG--------DGIIRQLDESEDRLWREALNLSIRLGSEDIMTSLLLGVKFDFRQIHEALLVAVDTNQPRFVKHLLDRLDLEKGNKMDVRSFSMAIFDHSIDDSQFAPGVTPLTLACQKDLYEIVMMLTQRGHDIPLPHAISCTCLECNNGRQYDLLKFSLSRINTYRGIASRAYLSITSEDAMLSAFHLSKELRKLSKKEPEFKPQYLALEELCQEFAVELLGMCRNQSEVSTILNSAEGDSEDEELDE---QTFEEGIPNLARLRLAVNYNQKQFVTHPICQQVLSSIWCGSLSGWRGSRTTWKLLVSLGIFLTMPVLCLIYWIAPKSKLGKLLKVPVIKFLLHSASYMWFLIALLTESIFMEIYRTEFASRNQNILHNSLHMVWVAGFFWFECKEVWIEGLKSYFLDLWNILDMMVLSMYLASFTLRILIMLKGYFLCQDSSTQELCDYFTNTVRENWRQEDPQLIAETLFAVTSMLSFTRLAYILPAHESLGTLQISMGRMIDDMMRFMFILMIIGTAFLCGINNIYVPYVISPHLGRLNETFNFLFWTMFGMANQGYVDMPDYALAEFVGRIFYGIFTLLIVIVLLNMLIAMISNSFQRIEDDADVEWKFARSKLYLSYFREGLTMPVPFNIIPSPKAFFYILRGIFQKICC---CCQKKAPEYPPITSVSSNAMNSG-GGQGEGRVPYRLQVTKALVHRYIEAARREFEESTRKDVGNRITELNKVVGRLHTEMKDFQQKLKWQNK-GEPDQANILGKYIKGAKNNFRDFDK-------------------NEAMGCENVGLRFSTHPEEEKSKADEDVLME-EEEPESPVEIHPGEQSTAQTADE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*:*. ** *******:*** *: *****::. *:.**. . .* :*:::***** *******:**** * * ** .********************* .*::** **: ***.*:*.:***:*:** ***.*:*******************. :* ::** *. **.:**:****.*.*:*********************:**::******:**:**:***:*::*********:***.***::..************:::**. *** * * *:***********************:**************.*:***** * ***:*:: ******.**: **:****:**:***:**:*********:**** ** **:.** : * .*.*.: ..****:**:**:************:**:** **:**:::**:*****:**:*: .*: *:*:* . * ***.: *.:** ****::**.*****************************:*:*****:********* ******:******* : :**.:****:********* :: ****:: :.***** :*****:::************:****:**************************:******:***** **::* **: :** **: * .:**** :.:. . .:* *:** :*.***:* ****:****:*******: ***:***:***.*.*.**::*: ..*:.: . ** *.**.:**. .:*.*:::. . . : .* :. . * *.:. .**:. *:*.*.. :: : :: . ", "identical_positions": 546, "similar_positions": 202, "identity": "46.47%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-604", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AWP1-1", "uniprot_id": "A0A8I6AWP1_RAT", "id": "A0A8I6AWP1-1", "name": "", "aln": "MGFGRRGLTQERKMSILTSPRGKVEVVHCRRTESQDIFCIKTLIRKFTQKLFG-------RLNIIYLLEKANLAVTVCN-DKEEIMAHSIFVDYPNWNVAKQDNWIPVFR---ELDKEIPCTPLNTLFMHFFVAVDEYATGCLKEIIRTVFKAVPELYFIFLIVPTYLSLGSTLITVFDQVGNIPCMNYDEEFAVH---------ICHRHDHYPQLHIRKARVEDHDDLMPIFMHYDSTLKEIYGEYFLAELIEAQ-----DEDNHAVVCEVEG------KAVGFMSVCASVNLPLLHECFDLGPFHGFCFPHPD----------DLLEPPKEPSLEESEDTGNKSDSQ-------GSQRVVEEPVSIDTSEMIQEKDTETSISCEEVLS-LLSKVSED--MQDLEKNLSIISLVDEDDFGSLSSLSSSLLLSVESSHFRPLYLGESAAFCIQLFCIDERYEAR---------SLDFMSFVFSLFPNKNFCLISVPH----LTPEFVLIQNFVKVVPFSN-CTLDNDLYVFHRAGLLRSITIRLAKFLDTPGVEKLVRTLLLSTK------------------------ILSDLAQYNEAGRDPDGTELQVFVAEVAN--------QIVGIAVIRKEMDIEYIRSHYNIEDFIYFSHHQQEEHGRLNHFALNPIFRHYTKFFLKEILRLGYKSCLYYPVYSQTREGKLQSSYAHSLTSALHYLVPVRPRRQIVYPLEKLGINAPSKEVSKDQASYALNHTNRKLTLEPKVTVNARIVVVGASSVGISFLETLVFCSHLK-------FNNLTLISTHGLPGKKLLSNEQRKFLASDHCFNDK---------------DYVLMSLCSWVNVVVGRMTAIDRVAKQVVVSKDEIVFYDHLILCTGQQYQVPCPTGADIEQHLTNREVMQLSKRRYTGTVPSNLFILNDEEDCVRALFWLRNNSTLTEG--KVIVYGNTLDAYTTVETLLHIGMEGNCIYFVHPPAESNTTYIN--------NYDIESAVDEALSAAGVKVYQDALLAQWNQGQDPDPIQNACFTTS--TKPFRLECSAFFSFYKKNVDYETFKAFNDACLVYDG-RLVIDTTFHTNDIAIRAAGPLTKFSNRYYSNEWTHSNFSSKEIGFQLAAAMLSLFDPTLEPVTEPPADLDRLIPMYKGAKIQGGILPGSYHYLHISKPAIPTPLDVQRSQPDFGSEIVTGNAKKGTYFRLYFNNYKLVEAITCFSKEPFPTSNYIRLFGQHEQVLNNLCTRFDEKLIPDLYSYFTEPWCMALFHDRFIDLKKELRQIITSKQEEDQP---TMEQIARQLEEEEINLNEKPQKYLQKVFEDSIYKSLLEKSILDYLHYNQYHLPMYAWPGII------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CEL2-1", "uniprot_id": "CFA61_MOUSE", "id": "Q8CEL2-1", "name": "Cilia- and flagella-associated protein 61", "aln": "-------------MSILTSPRGKVEVVHCRRTESQDIFCIKNLVRKFTQKLFG-------RLNIIYLLEKANLAVTVCN-DKEEIMAHSIFLDYPNWNVAKQDNWIPLFR---ELDKEIPCTPLNTLFMHFFVAVDEYATGCLKEIIRTVFKAVPELYFIFLIVPTYLSLGSTLITVFDQVGNIPCLNYNEDFAVH---------ICHRHNHYPQLHIRKARVEDHDDLMPIFMHYDNTLKEIYGEYFLAELIEAQ-----DKDHHAVVCEVEG------KAVGFMSVCTSVNLPLLHECFDLGPFHGFCTPHPD----------DILKPSREPSLEEGEEKHLKKCSTSLIIREMQIKTTLRFHLTPVRMAKIKNSETETSASCEEALPTVLGLVSEERLKQDMEKNLSILSLVDEEDVA--SSLSSSLLLSVESSHFRPLYLGDPIAFCIQLFCIDERYEARQVLISNVSLSLDFMSFVFSLFPGKNFCLISVPH----LTPEFVLIQNFVKVVPFNN-CTLDHDLYVFHRAGLLRSITIRLAKFLDTAGVEKLVSTLLLSTK------------------------ILDDLAQYNEAGRDPDGTALQVFVAEVAD--------QIVGIAVIRKEMDIEYIRSHYNIEDFIYFSHHQQEEHGRLNHFALNPIFRHYTKFFLKEILRLGYKSCLYYPVYPQTREGKLQSSYSHSLTSALHYLVPVRPRRQIVYPLEKLGINAPSKEVSKDQVSFALNHTNRKLTLEPKVTVNARIVVVGASSVGISFLETLVFCSHLK-------FNNLTLISTHGLPGKRLLHNEQRKFLASDHCFNDK---------------DYALMSLCSWVNVVVGRMTAIDRAAKQVVVSKSEIVFYDHLILCTGLQYQVPCPTGADTEQHLTNREVLELSKQRYTGTVPSNLFILNDEEDCVRMLCWLRNSSILTEG--KVIVYGNTLDAYTTVETLLNIGMKGSGIYFVHPPTESNITCIN--------NNDVESAVEDALSAAGVTVFHDALLAQWNHGQHPDPIYNACFTTS--TKPIRLECSAFFSFYKKNVDYETFKAFNDACLVYDG-RLVIDTTFHTNDIAIRAAGSLTKFSNRYYSNEWTHSNFSSKEIGFQLAAAMLSLFDPTLEPVTEPPADLDRLIPMYKGAKIQGGILPGSYHYLHISKPAIPTPLNLQRSQPDFGSDVVTGNAKKGTYFRLYINNYKLVEAITCFSKEPFPSSNYIRLFGQHEQVLNNLCTRFDDKLIPDLYSYFTEPWCMALFHDRFIDLKKELRQILISKQEEDKP---TMEEIAYRLEEEEINLNEKPQKYLQRVFEDSIYKSLLEKSILDYLHYNQYHLPMYAWPGII------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NHU2-1", "uniprot_id": "CFA61_HUMAN", "id": "Q8NHU2-1", "name": "Cilia- and flagella-associated protein 61", "aln": "-------------MSVLTSPRGKVEVVHCRRTESQDVYCIKSLIRKFTCKLFG-------KLNIIYLLEKANLAVTLCN-DKEEIMAQATFLDYPNWNVAKQDDWVSVFR---ELDSDIPCTPLNTLFMHLFVAVDEYSVGCCKEILRTVYKAVPELHFIFLIVPSYMSLGSTLITVFDQVGNIPCLTYEEDFAVH---------ICHRHSHYPQLHVRKARVEDHDDLMPIFMRYDTILKETYGEYFLAELIEAQ-----DEENHAVVCEVEG------TAVGFMSVCSRVNMQLLHECFDLGPFHGLCFPHPD----------DVLESPQDLSVRRSQDAELRSSSQG----SQKIVEELQEPVSPDTMENIQGNIAREAASEEALTAVQSGNVSEP---EDIEK-LSDISTGYAQYHHVSSRSLASLVLPEEPVHFRPIYRGASAAFCIQLFCIDEKYEAR---------SLDFMNFVFSLFSDKNFCVISLPH----LTPEFFLIQNFVKMVPFNT-CTLEQDLYVFHRAGLLKSINIRFATLLDTPGVENLVSTLMLNKS------------------------ILEDLDRYNKARKDPDGTLLQAFVAEVAE--------QIVGIAVIRNEMDIEYIRSHYNIEDFIYFSHHQREEHGHMHHFALNPIFRHYTKFFLKEILRLGFKSCLYYRVYPKSREGKFQNPYAHSLTSALHYLVPVRPRRQIVYPLEKLGINAPSKAVSKDPMSYALNHTNRKLTLEPKITVNAKIIVVGASSVGISFLETLVFCSHMK-------FNNLTLISTHGLPGKKLLDTEQRKFLASDHCFNDK---------------DYALMSLCSWVNVVVGRMTGIDRAAKHVVLSTDEIVPYDHLILCTGQQYQVPCPTEADISQHLTNREVPNSSQRRYTGKVPCNHFTLNEEEDCFKALIWIRNNSITTEG--NIIVYGNTIDTYTTVETLLNLGVSGSRIHLVQPPPASTITCIN--------NYSVESAVADALGAAGVTMYRDAILAQWNDGLHPDPIYSASFTTP--TKPFRLQCSMFFSFCEKNVDYETFKALNDACLVYDS-RLVIDTNFHTNDIAIRAAGSLTKFSNRYYSNEWTHSNFSSKEIGFQLAAAMLHLFDPTLEPVTEPPANLDRLIPMYKGAKIQGGILPGSYHYLHIAKPAIPTPLEVQMAQPNYGLELVTGSAKNGTYFRIHINKYKMVETITCLSREPFPASNYIRLFGQHEQLLNNLCARYDENLITDLYSYFTEPWCLALFHDRFIDLRKELRQILASKEEEDLP---SIEQLAHQIEDEEINPTEKPRQYLKRVFEESIYKTLVERSTLDYLHYNRYHLPMYAWPGIV------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YU94-1", "uniprot_id": "A0A8M6YU94_DANRE", "id": "A0A8M6YU94-1", "name": "", "aln": "-------------MSTITSSTGKAESVTVRRTEWSDAEEINHLISPASVAVFG-------RLNVINLLEKANLAVTLSS-SKNEVLAHASFSDHPIEELVDQACWQNRLQNYASAEKLTVGRPMNTLFLRLFVAQPGFSIGGAKEIFRTVFSAVVELEHICLLTPYGGALEAALQKIFEPMT---SVTDEAQYSAY---------VCHRHDHCPRLHIRKARVEDHDDLMHIFGEQITPLVETYGPFVLSELIETQ-----EQEHHTAVCESDG------AVVGFISVSAHVDLKLLNKCFELGAFEGLTKTDPS----------QQEEPHQLEEENPADDAQQ----------------------SDETNEPVEG---EQTAEEETAGGDQYTDISQT---EYTEPCIKETVDCCEDSEP----------------------DGPSNAFCIQLFTMEKKFEMR---------SADFLPYLFKLFPERDFCVISVPK----QAADFPLLQSFIRVAPRDT-STFPQELYLCHRWGLTRRLEVRVAVSSDIPAVQSLTESLSQRDS------------------------IIEDLDLFLQARKNSDGTALQAFVAHVDG--------RVVGLIITRDEEDIEFIRANFDIERFMYFSHNQREEHGRLCHFLLSPVFQHYTKYIFREVLRLAHKSCLYYLLPPP--HDCYKNVSAHSLTAVLNFMVPVSPRRQIIYPLEELGINAPSQHITKLQAPFALYHTNRKLAMEPKVTINARIVVVGASDTALAFLEALTFCPHLR-------FNNLSLISTHALP--DHSSDDCSTFLATSHCYNDR---------------DQCQISLCSWISVVTGKIKAINRADKHVELMDDSRVKFDYLILCTGLQYQMPNLSNADVITQTSNSLKPKETRPR----VPSNLFLLNDHQDCSVAHHWLTHNFTQLTG--DAVVYGNTIDVFTCIETLIGLGVSGRRIHVVHPPEDQPFSCFP--------DASVELAVKQALEKEEVHVHHNCLLLQINDGQHTEPVTSASFSTD--GAILQLECAVFFSFSRKSVDCDAFRAINDACLVFDG-RLVVDSGFHTNDPSIYAAGPMTKYSRRYHAEEWSHCCFQSKEVGQSLASVLLAQCDPTLERPVDPPPDQLHLIPLYSQAKTQGGRLPGGYNYLHVAKPVARKTPSAHK-----GRDLVTGCAETGNYFHIRHSQFDVVEKITCLSKTPLPVSNLQSLYGKHQRLLNNICSRYDEGLIQDMYSYFKENWCLALYHDRFADFEQEVCQIMDSAKLQDESGSVSLEEALQQIADDKAESDQ--LVSLSQTFQKSQAYSALRNSVLDYLKYNRYHLSMYARPGLL------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W206-1", "uniprot_id": "Q9W206_DROME", "id": "Q9W206-1", "name": "", "aln": "-------------------MTTSNDNILIVTAGIRDQRRIEDLYDAKSTWHFG--VKETPPLDTLFLKNQAQRLIVYNKQEYHLLLAYSEFANHPNIPVLANDLWLHWLN--VRFCVDLPITLLNAIFFNFFICKDGHSQ-MLKKVILEVFYTEHLVNYMLVFKPPDCPP-----GQYDAVQAFGTTYYPKHSKVSEQKHLPAVIVIQRRSTMPVLSFRKALPEDNDDIVEMIDSEDPELRKKHGDFYIAEHLLNAEGSDSDHNDKIIIAEFEEEIADNVKGAGLMWLSQSLDIKMLATNYHLERLGNLVRYTPGCTHAHVGFEVISVELKSYKELFTRKQMEER---------------------YKSHVSRIN---------TDGQDETRNILFKKYK--HIYEELREGVYYITAHQDKLEISFDLPDGEKSTSENRLQYLAKASNGFLLKMFQLHPLVRYEY--------TFYSLSAMFSAFPDHDYCVTLVPANVSTSPCQRELLRFFLPVAHRPS-STVSENLFVAHRSTLFGELRVHRFESQEIDEIRTLISKQARKRESLSEDDSE-----DSKGIDNYTEDVLSIFEDIIREILEDPMCDLTCFTIRCGQSKKHT-DCPLVGFIILRPFLVYDDISKIFMMPRDQFSLTHKR---GEIVMFRLHPFFQMWCKTILRTVALCDNYRELYYIHFFSG-ISLPNDLMYNMMPIEPRRMKKNLFNYKCVSLRRRVAKGKMSVNVSMDICTSRMRLFCHNLQPTMHMGGKNSLLIVGFSSTCMAFLRTVIFAWNSKDLINYKKYNCLPMVDITVLVGHGIIESAYDCDFSCNFCANARNCYVDTGNVNPFVRDTMQRMDVRHWVRFVSGEVKSIKRQEKVVELSDGCHLYYDKLVLMGATRYGFEDKEFKGH-------------------PIPLNYVVNNTRLDRIIFYHKVCEMVELMES-YYIIVYGYNLCIYECIHFLVTHGCKAQNIIYVQPHVPIVMEDLGIPEK----DSRLDPIILEMIADLGVTIYLSTNYSQFILSQDNMNIEKVELIMHPSKKKIVLHCDLFVNYNDNTISSSMENVLSEAGIEISERRIVVNSRYCTNDRNIFAAGINVIMIP---KPNFQYTYGSPQEMAEKLAYELNMIK-VVMQSRYSKPYMFTGILPMG----------------YQIIKITQPKPLLIGQLPIEFSETLTT--YDDGDFCRIRLNNKLIVIEIVCVTKKPKRLYFMEYFCGKHAMLLNDLRGRFQAGWIQNFLDFFQQPWTELLMHDRFEDLQLKNRRLLLSMLLMNNKD--TNN------PRNSLENTQRLRLEENVIDFVRTYRKDFTHEFALPEDWGVFNL---------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KVK5-1", "uniprot_id": "Q7KVK5_DROME", "id": "Q7KVK5-1", "name": "", "aln": "-----------------------MNQFQIRLAQAGDQDGLNKLIRSPGVKWFGNIRPKFRGKDSLFNSYQTYRILAFCT-ESSALVAYAEFRNYPSIAALPTDCWLEWLS--TRYCLSMSISWLNALFFNFCVYKSDQSP-VLVEIIKDVLYRESRVWFLITVRCPYVPQPIHFVETFDDLEKISQVFYPLEYSMDKNNNTQSLYIVDRFVILPRITYRKALAEDNDDIIAMQEVENPEMREELGDYYIAEEVMGQ------NPKSMLVVAETINQSQESEMAIFLWLSSDIDIMFYVRNYEMEQFGNLVKPADGRSFHYETMTVSSVQRRAEASMFTADALDDLNAVTILGGLQKVDSGMSVASLGKMKVSSIGGTIVDTNVANENKFYMRECLYSKFK--YILEKLHSTDYYLRHEQSVINFIYPAG-----TEPAGPAAMAAASNVFLLRCIVARQDFPLPR--------LFNAMVAIFSAYPDRDYCMMLMSVKYKASKSYLEVMQYFMPVASRPSNLSSLDDVFITHRSTIFGEISLYKLEKEDVAHVHKLALGNLPSNTQTPNSSSSSFSYCSKVNEREELEHELHVLDAIMKDVLENEFSEFAVFTIRCGISTRSVRENTAIGFVIVREFHSHEKLFEHYHLPKQEYQLNRRR---AEIISLRLHPLFLVSAGLIFRDLARKTSFYDYYFIHSVDG-YKYSNDLKKMMMVVEPKPIKK-VPVFTRVQANHKKPRKKLDLPP-PNFSRDNLIIYRHKLNPVKWFTNSQKLVIIGFSAVTKAFLRQLVFQWNSKDHKNSENFTCLTRLQVTVICRAGIVEADYDSLFKCPYCTNRQGCYLSYRNESCYVRDCCMRIDLRCWVHFVPGKVEKVDRDKKFVKLDS-CEIYYDTLLLMCDRMFVLRCIDVPVYS------------------PRPCNLVEINFRLNKFLLFYKVRALLEDMPRTYLVLVYGNNLHTYECIAFLIGHGVDCSRMVFVQPHR-ITGRDADMKEKCPYWDKNLQMIMDDILVEKGVNIFTDYDFHHYNLHKSTDFIMEVIFQHFPTQKQMTFECDLFISFQEGHLHQRHKQWLENAGIELDGNQILVNERYQTNDPDVYAAGSFIKMRI---TPNYQYKFVSERELARKILHHLGIVTDKNFEDRFAEPVLFQAILPLR----------------YFITKVTMPRRYLLSQVPVIKNCNLTT--YKNKTFCRVGLSTRMMVDEIVVVTKKECNLDFLLYFCGKHELLLNKLKSRYRANLIHCFLKFFQEPWTELIMHDDFEELQAENKELLSPMAISALSR--PGRGALGELTDMDFFTLNKRYIELKLLTFLREHRRDFRHKFALPEDFLKLDLADYERYMDTEENDSSSDLSET", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : * :: * ** : : :: :. . . ::* : * ::* * : :*::*:.: : : ::: * : .: . . :: : . : .* * : *** **:**:: : : : * : ::* : . . : . :: :. ::: : :.: : .: . : . . : : .: * . . . * :: : : :*. :. :::*: :. ::: *: :. . : .:::: ** : : : : :..* : : . : : *. . :*: : * : : : : : .:: ..: : * *.* ::: : *: :. : . : : .. . : ::* . . ::::* * . :**. : * : : :. *. :. : : .* * : :.: *: .* *.: :.* * * : : :* *:* : . * * . * . : : :*** .: : : *: * . : *:* : :: : : : * :. . : : .. : : :.* *..: : . :.:* : . ::::: : *** : *** :: : . :*:. .: : :: * ::*: : * . . :.* . : :: . :* *. .:: : *:* :**.: *: * : .:* : * : ** * ::. : .:: . . . . : . . .. .: .* ", "identical_positions": 94, "similar_positions": 298, "identity": "6.74%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-605", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q67BT3-1", "uniprot_id": "S13A5_MOUSE", "id": "Q67BT3-1", "name": "Na(+)/citrate cotransporter", "aln": "MDSAKTCVTKFKSFAILLFTPILMLPLVILIPDKFARCAYVIVIMAVYWCTDVIPVAVTSLLPVLLFPLLKVLDSKQVCIQYMKDTNMLFLGSLIVAVAVERWKLHKRVALRMLLFVGTKPSRLMLGFMFVTAFLSMWISNTAATAMMIPIVEAMLQQMIAANTAVEASLGTLELLDKNKTSELPGS-----QVVFE----DPNVQEQEDEETKNMYKAMHLCVCYSASIGGTATLTGTGPNVVLLGQMQELFPDSKDVLNYASWFGFAFPNMVMMLVLAWLWLQCLYMRHNLKKTCICCGEKKRDTEKIAYKVLNEEYQKLGSLSYPECNVLFCFTLLVILWFSRDPGFMPGWLSFAWVEGNTVHITDATVAIFVAILLFIIPSQKPKFNFSSQTE---EERKTPFYPPALLDWKVAQEKVPWDIVLLLGGGFAMAKGCETSGLSKWMAAQMEPLRLVKPAVITLILSCLVAMTTECTSNVATTTLFLPIFASMARSIGIHPLYVMIPCTMSASLAFMLPVATPPNAIVFAYGHLRVVDMMKTGLIMNFVGILSVFLSVNTWGRAMFNLDNFPDWANSTSVNT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86YT5-1", "uniprot_id": "S13A5_HUMAN", "id": "Q86YT5-1", "name": "Na(+)/citrate cotransporter", "aln": "MASALSYVSKFKSFVILFVTPLLLLPLVILMPAKFVRCAYVIILMAIYWCTEVIPLAVTSLMPVLLFPLFQILDSRQVCVQYMKDTNMLFLGGLIVAVAVERWNLHKRIALRTLLWVGAKPARLMLGFMGVTALLSMWISNTATTAMMVPIVEAILQQMEATSAATEAGL---ELVDKGKAKELPGS-----QVIFE----GPTLGQQEDQERKRLCKAMTLCICYAASIGGTATLTGTGPNVVLLGQMNELFPDSKDLVNFASWFAFAFPNMLVMLLFAWLWLQFVYMRFNFKKSWGCGLESKK-NEKAALKVLQEEYRKLGPLSFAEINVLICFFLLVILWFSRDPGFMPGWLTVAWVEGETKYVSDATVAIFVATLLFIVPSQKPKFNFRSQTE---EERKTPFYPPPLLDWKVTQEKVPWGIVLLLGGGFALAKGSEASGLSVWMGKQMEPLHAVPPAAITLILSLLVAVFTECTSNVATTTLFLPIFASMSRSIGLNPLYIMLPCTLSASFAFMLPVATPPNAIVFTYGHLKVADMVKTGVIMNIIGVFCVFLAVNTWGRAIFDLDHFPDWANVTHIET", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B734-1", "uniprot_id": "A0ACD6B734_DANRE", "id": "A0ACD6B734-1", "name": "", "aln": "MLPLIKSIWNLKNGIVLFFTPLILLPLPLVISTREASCAYVIILMAVYWCTEALPLAVTSLLPAVLFPMLGIMQSKMVCMQYLKDTNMLFVGGLMVAVAVEHWNLHKRIALRVLLIVGVRPALLMLGFMGVTAFLSMWISNTATTAMMVPIVQAVLEQLNKQETEPLQMTCGVERPRTPEAEYKHAAKDRDRQVVLRMLDVSPEVRQKELAEKRHMAKGMTLCVCYAASVGGTATLTGTGPNLVLKGQMNQLFPENGDVINFASWFGFAFPNMIIMLTIAWLYLQFIFMGFNIRKTWGCGAVKSE-KEIAAYNVIREQHLQLGPMCFGELSVLALFSLLVALWFTRDPGFVAGWATHTFNI-EAEYVTDATVAVFIAMLLFVLPSKPPQLCFSSSTRSETESQRSSAPGTALLSWKVVQKKLPWNIVLLLGGGFALAKGSEESGLSRWLGNQLTPLHSIPPWTVVIILCLLIAIFTECTSNVATATLFLPVLASMSQSVGINPLYIMVPCTLSASFAFMLPVATPPNAIVFSYGYLKVSDMAKTGIMMNIIGIFCITLAINTWGKAMFNLDSFPAWANQTVI--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . : ::*. :*:.**:::*** :::. : . *****::**:****:.:*:*****:*.:***:: :::*: **:**:*******:*.*:******:*:****:*** ** **.:*: ****** ***:*********:****:***:*:*:*: .: * . ::. .: **::. .* : ::* * :.: *.* **:**:**:************:** ***::***:. *::*:****.******::** :***:** ::* .*::*: * ... .* * :*:.*:: :**.:.: * .** * *** ***:*****:.** : :: :: :::*****:*:* ***::**: *:: * *.*. *.:::. ..**.***.*:*:**.**********:***.* **** *:. *: **: : * .:.:**. *:*: *********:*****::***::*:*::***:*:***:***:***************:**:*:* ** ***::**::*::.: *::****:*:*:** ** *** * : ", "identical_positions": 294, "similar_positions": 183, "identity": "50.34%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-606", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PGC1-1", "uniprot_id": "DHX29_MOUSE", "id": "Q6PGC1-1", "name": "ATP-dependent RNA helicase DHX29", "aln": "MGGKNKKHKAPGAAAMRAAVSASRARS-----AEAGAVGEAQSKKPVARPAPAVPTGA-------REPRVKQGPKIYSFNSANDSGGSANLDKSILKVVINNKLEQRIIGVINEHKKQNSD-RGAISGRLSAKKLQDLYMALQAFSFKTKDIEDAMTNTLLHGGDLHSALDWLCLNLSDDALPEGFSQEFEEQQPKSRPKFQSVQIQATLSPPQQTKTKRQEEDPKIKPKKEETTVEVNMKEWILRYAEQQ-----DEEEKGEGSKGLEEEEKFDPNQRYLNLAARLLDAKEQAAAFKLEKNKQGQKEAQEKIRKFQREMETLEDHPIFNPAIKISHQQNEKKKPAPATEAESALNLNLFEKSAAATEEE----KGKKKEPHDVRNFDYTARSWTGKSPKQFLIDWVRKNLPKSPNPSFEKVAVGRYWKCRVRVVRSEDDVLVVCPTILTEDGMQAQHLGATLALYRLVKGQSVHQLLPP----TYRDVWLEWSDEEKKREELNKMETNKPR----DLFIAKLLNKLKQQQQQQQQ-QRPESEKGGSEDPEESWENLVSDED-----LAALSLEPTSAEDLAPVRSLFRRLQSTPKYQRLLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLDECGARKCNIVCTQPRRISAVSLATRVCEELGCESGPGGRNSLCGYQIRMESRASESTRLLYCTTGVLLRKLQEDGLLADVSHVIVDEVHERSVQSDFLLVILKEILQKRSDLHLILMSATVDSDKFSTYFTHCPILRISGRSYPVEVFHLEDIVEETGFVLEKDSEYCQKFLEEEEEITINVTSKAGGVKKYQEYIPVQSGASPELNPFYQKYSSRTQHAILYMNPHKINLDLILELLVYLDKSPQFRNIEGAVLIFLPGLAHIQQLYDLLSSDRRFYS-ERYQVIALHSVLSTQDQAAAFMFPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGRVRDGFCFRLYTRERFEG-FLDYSVPEILRVPLEELCLHIMKCDLGSPEDFLSKALDPPQLQVISNAMNLLRKIGACEPNEPKLTPLGQHLAALPVN-VKIGKMLIFGAIFGCLEPVATLAAVMTE-KSPFITPIGRKDEADLAKSSLAVADSDHLTIYNAYLGWKKAQQEGGFRSEISYCQRNFLNRTSLLTLEDVKQELMKLVKAAGFSS--------SPSWEGRKGPQTLSFQDIALLKAVLAAGLYDSVGKIMCTKSVDVTEKLACMVETAQG----------------------------------------KAQVHPSSVNR---------------------------DLQTYGWLLYQEKVRYTRVYLRETTLITPFPVLLFGGDIEVQHRERLLS----VDGWIYFQAPVKIAVIFKQLRVLIDSVLRKKLENPKMSLEN-------DKILQIITELIKTENN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZHW0-1", "uniprot_id": "D3ZHW0_RAT", "id": "D3ZHW0-1", "name": "ATP-dependent RNA helicase DHX29", "aln": "MGGKNKKHKAPGAAAMRAAVSASRARS-----AEAGAVGEAQSKKPVARPAPAVPTSA-------REPRVKQGPKIYSFNSANDSGGSANLDKSILKVVINNKLEQRIIGVINEHKKQNND-RGVISGRLSAKKLQDLYMALQAFSFKTKDIEDAMTNTLLHGGDLHSALDWLCLNLSDDALPEGFSQEFEEQQPKSRPKFQSVQIQATLSPPLQTKTKRQEEDPKIKPKKEEKSMEVNMKEWILRYAEQQ-----NEEEKSEGSKGSEDEDKFDPNQRYLNLAARLLDAKEQAAAFKVEKNKQGQKEAQEKIRKFQREMETLEDHPIFNPAIKISHQQNERKKAPLATDGESALNFNLFEKPAAATEEE----KGKKKEPHDVRNFDYTARSWTGKSPKQFLIDWVRKNLPKSPNPSFEKVPVGRYWKCRVRVVKSEDDVLVVCPTILTEDGMQAQHLGATLALYRLVKGQSVHQLLPP----TYRDVWVEWSDEEKKKEELNKMETNKPR----DLFIAKLLSKLKQQQQLQQQRQHPENKTETAEDPEESWENLVSDED-----LSALSLEPTGAEDLEPVRNLFRRLQSTPKYQRLLKERQQLPVFKHRASIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNDCGARKCNIVCTQPRRISAVSLATRVCEELGCEGGPGGRNSLCGYQIRMESRASESTRLLYCTTGVLLRKLQEDGLLADVSHVIVDEVHERSVQSDFLLVILKEILQKRSDLHLILMSATVDSDKFSTYFTHCPILRISGRSYPVEVFHLEDIVEETGFILEKDSEYCQKFLEEEEEITINVTSKAGGIKKYQECIPVQSGASPELSPFYQKYSSRTQYAVLYMNPHKINLDLILELLVYLDKSPQFRNIEGAVLIFLPGLAHIQQLYDLLSNDRRFYS-ERYQLIALHSVLSTQDQAAAFMLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGRVRDGFCFRLYTRERFEG-FLEYSVPEILRVPLEELCLHIMKCDLGSPEDFLSKALDPPQPQVISNAMNLLRKIGACEPSEPKLTPLGQHLAALPVN-VKIGKMLIFGAIFGCLEPVATLAAVMTE-KSPFITPIGRKDEADLAKSSLAVADSDHLTIYNAYLGWKKAQQEGGFRSEISYCQRNFLNRTSLLTLEDVKQELMKLVRAAGFSS--------STSWEGKKGPQALSFQDIALLKAVLAAGLYDSVGKIMCTKSVDVTEKLACMVETAQG----------------------------------------KAQVHPSSVNR---------------------------DLQTYGWLLYQEKVRYARVYLRETTLITPFPVLLFGGDIEVQHRERLLS----VDGWIYFQAPVKIAVIFKQLRVLIDSVLRKKLENPKMSLEN-------DKILQIITELIKTENN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z478-1", "uniprot_id": "DHX29_HUMAN", "id": "Q7Z478-1", "name": "ATP-dependent RNA helicase DHX29", "aln": "MGGKNKKHKAPAAAVVRAAVSASRAKS-----AEAGIAGEAQSKKPVSRPATAAAAAAG-----SREPRVKQGPKIYSFNSTNDSSGPANLDKSILKVVINNKLEQRIIGVINEHKKQNND-KGMISGRLTAKKLQDLYMALQAFSFKTKDIEDAMTNTLLYGGDLHSALDWLCLNLSDDALPEGFSQEFEEQQPKSRPKFQSPQIQATISPPLQPKTKTYEEDPKSKPKKEEKNMEVNMKEWILRYAEQQ-----NEEEKNENSKSLEEEEKFDPNERYLHLAAKLLDAKEQAATFKLEKNKQGQKEAQEKIRKFQREMETLEDHPVFNPAMKISHQQNERKKPPVATEGESALNFNLFEKSAAATEEE----KDKKKEPHDVRNFDYTARSWTGKSPKQFLIDWVRKNLPKSPNPSFEKVPVGRYWKCRVRVIKSEDDVLVVCPTILTEDGMQAQHLGATLALYRLVKGQSVHQLLPP----TYRDVWLEWSDAEKKREELNKMETNKPR----DLFIAKLLNKLKQQQQQQQQ--HSENKRENSEDPEESWENLVSDED-----FSALSLESANVEDLEPVRNLFRKLQSTPKYQKLLKERQQLPVFKHRDSIVETLKRHRVVVVAGETGSGKSTQVPHFLLEDLLLNEWEASKCNIVCTQPRRISAVSLANRVCDELGCENGPGGRNSLCGYQIRMESRACESTRLLYCTTGVLLRKLQEDGLLSNVSHVIVDEVHERSVQSDFLLIILKEILQKRSDLHLILMSATVDSEKFSTYFTHCPILRISGRSYPVEVFHLEDIIEETGFVLEKDSEYCQKFLEEEEEVTINVTSKAGGIKKYQEYIPVQTGAHADLNPFYQKYSSRTQHAILYMNPHKINLDLILELLAYLDKSPQFRNIEGAVLIFLPGLAHIQQLYDLLSNDRRFYS-ERYKVIALHSILSTQDQAAAFTLPPPGVRKIVLATNIAETGITIPDVVFVIDTGRTKENKYHESSQMSSLVETFVSKASALQRQGRAGRVRDGFCFRMYTRERFEG-FMDYSVPEILRVPLEELCLHIMKCNLGSPEDFLSKALDPPQLQVISNAMNLLRKIGACELNEPKLTPLGQHLAALPVN-VKIGKMLIFGAIFGCLDPVATLAAVMTE-KSPFTTPIGRKDEADLAKSALAMADSDHLTIYNAYLGWKKARQEGGYRSEITYCRRNFLNRTSLLTLEDVKQELIKLVKAAGFSSSTT-----STSWEGNRASQTLSFQEIALLKAVLVAGLYDNVGKIIYTKSVDVTEKLACIVETAQG----------------------------------------KAQVHPSSVNR---------------------------DLQTHGWLLYQEKIRYARVYLRETTLITPFPVLLFGGDIEVQHRERLLS----IDGWIYFQAPVKIAVIFKQLRVLIDSVLRKKLENPKMSLEN-------DKILQIITELIKTENN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T8I5-1", "uniprot_id": "A0A8N7T8I5_DANRE", "id": "A0A8N7T8I5-1", "name": "ATP-dependent RNA helicase DHX29", "aln": "MGGKKKKSAAVSSSAQPAAAAAVTATN-----AASESTGKKQQQQ---RPNNEKTTSK---------ENKPRAPKTYGLNANAQTDTNSGSDKSILKVIIQPELEKKVIKLINDYRQEYAD-KGPISGRLTSKKLLDLYTALQKFQFKTEHIEEAMKSSVLYGGDLHSALDWLCLNLRDDELPEGFSQKMQEEKQKTRPKFQPLQEDRKQ---QGNKNQEPKEEEKPKAKTPVKDDGGSMKEWILRYAQQSEDQSSDEEQKEDIVHNPELDEKFDPNDRYLLLTAQLYDAKEMTTTSKAKKDKMGQRAAQDRIRVIQQEMKTLESHPVFNTAIKVKDTPKEEKKAAVVTDGKEELNFNLFEQAEAAPAEKNAVAEKKKKEPKDIRNFDYTSRSWTGKSPKQFLIDWCRKNLPKSPPPSFNKVAAGRYWKCKVRIQRP-TDVLEVCPTILTEDGMQAQHLGATLALYNLVKGQSVHQLLPP----TYRDVWLEWRDGEQKEEEQTLLAINKPR----DQFISRLLTRLKQQQSLQSQ-PEPQKLLQDAE-PEDSWENLDTQEEQE-PQCGAASGGPAGLVVEEASRRLLLKLQASPLARRLLDERKQLPVFQHREQVLEALRHHRVLVIAGETGSGKSTQIPQFILEELLAAGDTAQPCSVVVTQPRRISAMSLACRVSQELGSEDGPGSMNSLCGYQIRMENRSSEATRLLYCTTGVLLRKLQQDRHLNSLTHIIVDEVHERSVQSDFLLTILKEVVHKRADLRLILMSATVDCQKFANYFNRCPVVSIPGRTFPVEVFHLEDIVEETGYVLEQDSEYSQKFVEEEEEVNIGITQKGGKTVQHQELIVRDSASGWDLGPELDHFSSRTRHILQYMNPNKINMDLILDLLAYLDKSPQFNAVDGAVLVFLPGLAHIQQLHDLLSTDKRFSSKDRYKLVALHSSLSSQDQSSAFTVPPAGVRKIVLSTNIAETGVTIPDVVFVIDTGRTKENRYHESSQMSSLVEMFVSKASALQRQGRAGRVREGFCFRLYPKFRFES-FIDYSIPEILRVPLEELCLHIMKCEYGSPEDFLSRSLDAPQQQAVCNAVSLLRRIGACQQDTHTLTPLGHHLAALPVN-VKIGKMLIFGAIFGCLEPIATIAAAMSE-KSPFATPMSRKEEANLAKSALAVANSDHMTIYKAYLGWRSSRTEG-TRAEMNYCRRHFLNRTALITIEEVKQELMRMVEQAGFVSSKLGRTPRPRPSTETKAPLSISTQDVCVVKATLTAGLYDNVGRILYSPSLDVQERVVCVVETAQG----------------------------------------KAHVHPSSVNR---------------------------FLQTHGWMLFQEKVKYSKVFLKDTTLISPLSMLLFGGDIDVQHRERLIS----LDGWICFQAPVRIGVIFKHLRKLIDSLLERKLANPKMNLED-------EKTIQIIIELIKSENMI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06698-1", "uniprot_id": "YL419_YEAST", "id": "Q06698-1", "name": "Putative ATP-dependent RNA helicase YLR419W", "aln": "MAKKTKNNSKSSTPVNDVPTTAGKKKAKGKKGQEPEPEDDKRAKQQSNRAKVTSTASWTGKLPHTILHETCQKRKWNKVEYDMKKIGDKGFIAIAVLSFTDPKTKETLTARMNDPTYDKASGKGLVIPQETPIEARHMASTIALYRIAYN-TNLHMMLPPNHRKTWYALDDFRKDNLKTDEKRINKLFDLDPFKTMVEDRKLKAQREKEQVAQNNQAQKEQVARTILSSHGGISSSGKDRQERKVASHKNSHNPSLVRFPKKVWENSIFVDLDESSRQLIETSLKEKIDWQAKKISHKNETIAENREDLKAKLLTLQFRPKHVEEAMLYKDPLSFLLFNLPEDDLPPFFHKKKGDTKNKVEITNLPLSTR--MIVERLTEIGVSSDEALLALQQNDMNENEAAGFLTREILPTLNSNTNEPVSETESIECWNQELESLESIYEGCVMDAKEDSHYTLNLIEKLKIKLKVYRTKNYPASLPGIVVSTFDKNYKLPDYIKKQILTRLLHYLQEGNLIGDMLVYHIYEWLKENISKIIDNPGPLIPDSDSKGAINKRNISNGKRSINNSSSRKFTKTTISEDTLSVLREEYTKRIKSSEYKSMQLVREQLPAWKKQKVIIDIINKNEVVLITGETGSGKSTQVVQFILDFLQKEKGDFGKTKIVCTQPRRISAIGLAERVSDERCVTCG-----EEVGYVIRGVNKTKASTRIKFMTTGVLVRLLQNARTMLENTIVVIDEVHERSIDTDLIVTLMKNLLHRVRGMKIVLMSATVNVDLFKKFFPGLATCHIEGRTFPITDYFLEDILSDLDFKIKREKALSYDDDSVDERNN-------------------------------DDQYLKPRADSKFFTSGQINYDLLCQVVEYVHKRLKAANDNGSIIVFLPGVGEINKCCNLLANK---SNEADFMVLPLHSALTPEDQKRVFKK-YHGKRKVVVSTNIAETSITIDDCVATIDTGRAKSMFYNPKDNTTKLIESFISKAEVKQRRGRAGRVREGLSYKLFSKNLYENDMISMPIPEIKRIPLESLYLSVKAMGIKDVKAFLSTALDAPPLPALQKAERILTTIGLVDESDKSLTQLGQFISLMPVMDSKHGKLLIYGILFGCTDISVLLVSILGIGVLPFIGGFENREKIKKLLCKYESRG-DLFAVLEIVRDYFKIKDSS---IKRKYLRDNLLSYNKINEIKSSTAQYYSILKDVGFLP--------MDYKVGSISDLNRNERNFDILRAILTGAFYPHIARVQLPDVKYLSTSSGAVEKDPEAKMIKYWIRSEEYQDKLEEYKTKISQETQKVDLEDLPLPATRAFIHPSSVLFSTNSVNLEDAKLLSEVDGPISRQSKIPTVVKYPFVLFTTSQVTNKLYLRDLTPTTTLSLLLFGGAISYDIGGTIHSPGIVVDNWLPIRTWCKNGVLIKELRTQLDEAIRKKLESPDYAKKSQIDNSGADKTLKIVEKIIASEQ--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. *.*: .:.. ...:* . .. : :: *. .:. . : * .: .. . : . : : :: : :*: : . :* : : :. : .: :: : : : : * . : :: *: ** * . .:: : . : * : : ..: . . :* : ::. . * :. : . ...: . * : : * :. .:. : :: :* . : :*. ::: .:.. ... . . :. . * .* . . . : .* : : . .. . :: *: **. : : *. . :* : .. .: * .**. : :* .* : * . : * : * : * :*. : : * :: :: **:: . : . :: . :. : ... : . . * : :. : : *:***.:::: ::: :.::.*::::**********: :*:*: * .:* ********:.** **.:* * . ** ** .:: :**: : *****:* **: : . : :::*******:::*::: ::*::::: .::::******: : * .:* . * **::*: :.****:.: .: ::::. . . . :*. . :. :.: ::.. :** **: ::: *:.* : :*::::****:..*:: :**:.. . : ::.*** *:.:** .* * **:*::******.:** * * .*****:*. *: ..: :.*:* *:***.. **:*******:*:.::::.: :*. ::. .:*** *:***.* * : . : *** :**.* .: :* :* ** : . .** **:.:: :** * **:**:* :*** : . :.: : ** : .::: . . . * ::: : .: . : .. : .* : ::*. . : ::. . : ::. .** . . . ::. :::* *...:* :.:: . : .: : .:. :* :***** : .: ::*: . :::*:: * :.:.:***** *. : : * :*.*: ::: : .*::*.** :*. :.:** .*. :. :* ::*: ::* :*: ", "identical_positions": 248, "similar_positions": 483, "identity": "16.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-609", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JTA4-1", "uniprot_id": "A0A0G2JTA4_RAT", "id": "A0A0G2JTA4-1", "name": "", "aln": "MASAKYIPDETQLRSRRRHDLQEMLTEVGLSVDYWLPKHQEELGVTSAQALHYLDKRDLQ-----TQQTWEKRALERLLDLSHPNSV-AELHETPEEMIKTRQRQAGQALHALKALQSEGKCREEEAVRRREAELRQAMEIPEECWPVAEVSLKDITEIMEKHLSHMEQTLALSQNLSDGDLVRWASGGLALQGIYKSSHQKSLIQKREELLSVPKQFSLVGPERGMWIETKEFSSFQEQATFTHTIEMLGFSPNSLVKGEGWGLSLEAGMGQNKQTETDDTHKSHSEQSYFCSAKFSYVPLATCHFHINHLQLSKAALQELKSIEELLEQTT-HPDGFPLLRHRTENFFHRFGSHANQGPLHLGGIYCWKAISEGFKSEQLDDVKKQAEESLNMYIKGSYSGFGVKVGASVNMSDSHSKTASQSTTHENLKTKVQLSVAQTGGPAEANGIAQWTAGLVASNQTWSVIDRGLQLVPIWDIILSSHRTDFKDALQVANCLKDNYTALTGLAAQIQEGEEFLTAREEARLFLEDVKCWEVSDPEEQLNTLIHFMQTLSQKIKSYTIWINTCLTDWNLQNFLISIVNFCKNVPTNIIQFIKSQLCSLLEPHVYKVTNFPGAQYIIEWTNQSESKEEDIKITSFSEFIRTLKKTHTTLMEVNFKSESPETVEEAKRTATYEVTTALSSFMKYLRETEQPDMQLLVLTIAAGAGYQLVNSIFQHLLGCNELNFLVDQMQSNQHKYQELKNICNYRAQAFLVLTALRTTVEITDISTDDKEQRLTLIKQHMGKLLSEEVAHILTKHGAHHDWENLENDLRLLIDGDYKATTPP-LEMDEVKKQLQSLCHEKKQTYKQQSNDNNTKEMIENGPFLDLLQRLGLDHYYPKRMSRADFHLLYKTSVYNSQPRSEKELPFYFLQKLLMLDYGLRHLVFKNDENIKKQISIGSDDYENEDFDPYEDVIKDNDSLSYPSATESWPHIHPMDIQMAIFHCADDLTKQYILSKLSICQYALPLVVPNPNNSQIEFYLWSLRQIRKSWQESSESLQDQSYSHKNQQICRVSTPIVSFIRVGNGLSASKSQIMNSLLSKRKHDVFFHRHCRGSNKNCLMMEGVVEICWFCPAGQGEDIFDKCLTFTNLHGDAKEHCQQLTFLQDVSSLIVILMSASDNNKENQNFVRHLCQSPRPLICLIDDKEKVIANNSGKRMRIGIKNRNEAELTEELTNAIKHFLELSN-TALSLEDCSQIARKQGFLIDEDQR-DCKEAKEKAQIMMALLEECKLSQTKENLLPLQGQLWHLWCKKDKEFYHLREKGNRSIEQHKSEIETDKRTIRHQQLEKAFPLNDLMRSVLQLLQEYSETHNNLYFLQWLTLFFDNLTTEHLEKLHEKQRSLWLMVQREKQR-----AQKNSSLTLWQDQIETISTEIHDCTLGTEHLLREVGQIYEALEETSSS---IENLSVCLPQIAADLMIAGVPIELMDGDASYVPLKWVAAVFDKISEKVGDKRLFVLSVLGLQSSGKSTLLNALFGLQFTVSAGRCTKGAYMQLLKV--EETFTEELGFDFVLVVDTEGLRAPELNNKSK-NWDHELATFVIGLGNLTLINIFGENPSEIQDILQISVQAFLRMKQVKISPSCLFVHQNVGEVTVKDQTMEGRRRLEQKLDEMTALAAKLEECSNVTQFSDVIKFDANTHVYYFAHLWDGNPPMAPPNLRYSYNVQELRNAILSTAQQESRGRILKISNVKFRVQDLWKALVTENFIFSFRNTQELLAMSKLETMYNHWTWELRSHVLDLQNQLNNQIQNGKISTLTFSLLEDPLSKKYKTIKQEFDKYFEEDPDSETLVQWKANFEHKLLILKDALISDTRRKGDEFISLKR-SQETLNNQKSQYENELLERSRKLALSVNGKELTDEELYEKFNQLWTNWIHNVSSNVPHVTEPNIDLDSENILLEYFNKDKNIGERLKIKSGENF-EIIYAKHIQMKKIYGVLPESLETYHKESINEITNNIDLKVTEALKNIWKQKRDYSQNYFHEILRIIEN-ELKSEHCVKDYTFTRDYNIDLSLCLFQRASKEFKEIHEAFKSANDPVNYLERKKDDFFMSFKISCQGATSITSFVDFLWLKLTPAISVTIWEIIGPKVAGDMQATFPEFNGNRANLERHILYSLAEEENFDKYWQYLHHPEAFFRNYIRDHIRRYCLEKKGKKIKTFLKISLGDIKTAILSAIHESTAVAKDKGSTASGWLDLFCDHLGSNLVFPRRDLVSIEHQEITDTEFLKEAMSTALDPAMRKVEEDCSSKQMDEIIPDIEK---ILSEHLCG-CWKQCPFCKAICTNTIPQHEGDHSVQFHRPQAVSGWHKHKTDYFVIDCCTSSVASNHSFILHDLQKFPYKKYREAGGDFAMWSITPDSSTQPYWKWFVCHFKSELENKYGKKFINLGSIPDLWTKITKQDVLDDLRNNTCHKYDTRWAADFSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80SU7-1", "uniprot_id": "GVIN1_MOUSE", "id": "Q80SU7-1", "name": "Interferon-induced very large GTPase 1", "aln": "MATAKCFTDEPQLQSRRKHNLQEMLTEVGLSVDYWLPKLQEDLGVTSAQALQYLDRNDLQKLKSQTTHTWEKRALEKLLDFSQPNSV-AELQETPREMKKNRQRQAGQALQALKALQSEGKHREEEAVRRKEAELRQAMEIPEECWPTAEVSLKDITEIMERHLSHMERTLAHSPNLSDGDLVRWASGGLALQGIYKTNHPRSLIQKREELLSVPKQFSLVGPEHGTEIKTMEFSSFHEQAMFTETIKMMGFSSTSLVKGEGWGFSLEAGIDQNEQTASENTHQSHSEQTYFCSARFSYIPLATCHFHINDLELSNAALQELKTIEELLEQTTDHRDGLPLLRHRAENFFHRFGSHANQGPLQLGGIYCWKAISEGFKSEHLADVKQQTRESLNIYIMGSYSGFGVKVGASVNIANSNSETASFSTTHLHSQTKVQLSVAQIGGPAEADGIAQWTAGLVVSNQTWSVIDRELQLVPIWDIILSSHRTDFKNALQVANCLKDNYTALTELDAQIQEGEEFLTARKEAKLFIEDVKCWEVSDPEEQLTKLLDFMQTLSQKIKSYNIWINTCLTDWDLQNFLINTVKFCKTSPTYKTQFIKSQLCILLEPHVYKVTNFPEAHSIIQWINQSEYGEEQVKITSFSEFIKTLKKTHKYLMEVNFKNEAPETVEEAERTATYEVTTALSSFLKYLKETEQPDMQLLLLSIAAGAGYQLVNSIFQHLLGCDELNFLLDQMQSNQHKYQELKNICNYRAQAFLVLTALRTTVEITDISTEEKRQRLALIKQHMGTLLSEEVAHVLTKHGEHHDWESLENDLRLLIEGDYKATTHY-LQMDEVKKQLQSLCHGKKQTYKQKSNENITKGMIENGPFLKLLQRLGLDNYYPKRMSRADFHLIYKTSVYNSQPRSEKELPFYFLQKLLMLDYGFRHLIVKDDENIKKQISIGSSNHENEDIDPYDDVIIDNDSPGYPSATESWPHIHPLDIQMTILHCADDLTRQYIFSKLSICHYALPLVVPNPNTSQIEFYLWSLRQIRKSWQDASKSPQDKSYSHRNQQMCRVSTPIVSFIRVGNDLSASKSQIMNSLLSKRKHDVFFHRHCKGSNKHCLLMQGVVEICWFCPAGQGEDTFENCLTFTSLHGDAKEHTQQLSFLQHVSSIIVVLMSVSDNNKENQKLVRHLWQSSTPLICLIDDKEKAIANTSGKRMRIGIKNRNEAELTEELTNAIKHFLELSN-TVLSLEDCSQTARELGFIIDEDQR-DCKEAKEKAQTVMALLEEYKLSQTKENLLPLQGQLWHLWCKKDKEFYHLREKGNRSIEQHKSEIETHKRKIRRQQLEKAFPLNDLMRSVLELLQDYSETHNKLYVLQWLTLFFDNLTIDHLDKLHERQRSLWLRIQTEKQR-----AQKSNSV---QNQIEAISTEIHNCTLGIEHLLREVGQIYEALEETSSS---RDSLFLCLPQIAADLMIAGVPIELMDGDASYVPLKWVAAIFDKITEKVGDKRLFVLSVLGLQSSGKSTLLNALFGLQFTVSAGRCTKGAYMQLLKV--EETFTEELGFNYVLVIDTEGLRAPELNNKSQ-NWDHELATLVIGLGNLTLINIFGENPSDIQDILQISVQAFLRMKQVKISPSCLFVHQNVGEVTAKDQTMEGRKRLEQKLDEMTALAAELEECSNITRFSDVIKFDANRHVYYFAHLWDGNPPMAPPNPRYSYNVQELRNEILSTAQQESRGRILKISDFKFRVQDLWKALVSENFIFSFRNTQEVIAMSKLETKYNEWTWELRSHVLDLQNQLDNQIQNGKILTLTSNLLEEPLSRKLKTIKEEFDKYFEEDPDCEILVQWKANFEHKLLILKDSLISDTRQKCNEHISLKN-SQEILDNQKSQYENQLLERSRKLALNLKGKELSDEELHEKFRQLWTSWIYDVSSNVPHVTEPNIDLDSENILLEYFKKDKNIVERLKIKSQGKF-EIMYDKHIQMKKKYLLLRKSLETCHVESIKKTTNNIQLKFTETLTNIWKQKRDYSQNYFHEILRIIEN-ELKSEPCEGDYTFTKDYIIDLSLYLFQRASKDFKKMHAAFKTANDPVNYLERKKDDFFMSFKISCQGATSITSFVDFLWLKLTPAISVSIWKIMVQKIAGDMRATCPEFNGNRANLEIHILYSLAEEEKFDKYWKYIQKPEEFFRDYIRDHIKRYCSEKESEKIKTFLNISLGDIKNTILSAIHNSTKVAKAKGSTASHWLDLFCDHLGSNLVFPRKDLVSIEHQELMDTEFLKEAMSKALDPAMREVEEDCSSKHIDEIVPDIEK---ILSEHLCG-CWKQCPFCKAICTNTIPQHEGDHSVPFHRPQAVSGWHWHKTDQFHINVCTSSVASNISFILDGFREFPFKKYREAGGDYATWSITPDSSTQPYWKWFVCHFRSNLEENYGKKFTGKGSLPDLWTKITKQEVLNDLKK----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z2Y8-1", "uniprot_id": "GVIN1_HUMAN", "id": "Q7Z2Y8-1", "name": "Interferon-induced very large GTPase 1", "aln": "MATGEHTPDDPLLRGKRRQDLQEMLREVGLDVEYWLPKLQEHLGVTCAQALQHLDKNNLKKLKSQTQHPWEK-----LLNLSHSKSLSALLQESQVERAKRKQKQAEQALQELRDLLTEGKQRQEEAVRTREAELRQAMDIPEEYWPSPEEPLRELMENLQRQLNLMKWTLCHRQNLPDRDVVRWASGGLALQGIYKASHQRGLTEKREELLSVPKEFLLLGPQQGTQMKTKEFTSPQAEFMFTQMVEKLGFRLTTSAKDGNWGFSLEAGLDHSKHPESKETQQSSSENSYFCSTKFSYIPLASCHFPIDQLQLSKPAVQELKCIEELLSQTT-NPDRFSLLRHRIINFFHRFGSHVNQGPLHLGGIYWWKAISEGYCTEQLAEVRQQSAEALDIFIRDSYSGFGVKVAAGVNVSDSHSKTATQTKTSQNLQTKVQLSVAQTGGPPEADGLVQWKAGLIASNQTWCVIDRGLQLVPVWDIILSSHRSNFKDPLQVANFLKDSYTALTSITAQIQNGEELLSAGKEARVFLEDVKSWEVSDPEEQLKKLINFMKMLSQKLKSYDTWINICLTDS-LQNFLVNTINFCKKSSIYKTKCIKSHLRSLLDPHIYRVTNFPQAHFIMQWIFQSDSEQEQVNISQFSQLIEILKETQNNLMEVKVKSESPETVEEAQRKSTYEVSLALSCFLNYLQKTEQTDTQLLLLSIAAAAGYHVINNTFQSLLGCDELSFLLDEMQTAQNKYQELKNICSYRAQAFLVLTGLTATVGDTAISSEEKTQRMSLMRHHMGQSLSKEVAHVLTKPGADHDWENLEKDLRLLINGDYEEVTISSLQMEEVSK--QSLFYGKKQPHEPHDNENNKWEMIKNGAFLDLLQHLGLEHYYPKKLSKANFHLIYKTSVYNTQPSSEQELPFYFLQKLLMMDYELRYLVFKDDRNTEHQVHPNASDQEDEAFDPYENFFEDSDSPTKSSSTEPSPHIHPVDIQMTIFHCADNFARQYILAKLSTCQFALPLLVPNPCTSQIEFSLWSLRQITRSWQEARKSPKGKNY-YKNQQMCCVSTSIVSFVRVGNGLSASKSQIMNCLLSKRKHDVFFHRHCTGSRKDCLLMGGMVEICWFCPGGEDEDRFDNCVTFTNLHGDAKEHEQQLSFLKEVSTVIVVLMSASDDNEGNRKIVRNLWQSSRPLICLLDDKEATMTNISGQRMRMGIKNRNEAELTEELTTTIRHLLELSD-TALSLEDCSQIAHQQGFLIDEDQR-DCKEAKEKAQALMAFLGKMKLSQIKEKLLPLQGQLWHHWCKKDKELYHLREKGNQSIEQHKSEIETDKQIIRHEQLARALPLNDLMQSVLQFLQEHSEIHTKLYFLQWLSVFLDKLTAGHLEELHEKQKYWWSLVQTVKQK-----APNSHSLICLQSEIEAISTEISDCTLGIEQLIREVGQIYEALEEASS----IKKIFFSLPQIAADLMISGVPIELMDGDAAYVPLTWVAAVFDKVSEKLGDKRLFVLSILGLQSSGKSTVLNALFGLQFTVSAGKCTQGAYMQLLKV--EETFTEELGFDFVLAVDTEGLRAPEHSNKSK-DRDNELVTFVIGLANLTLINIFGENPSEMQDILQIVVQAFLRMKQVKIFPSCLFVHQNVGEATATDQTMDGRRRLEQKLDEMAAIAAEQEQCLDVTCFSDVIRFDVNTHVYYFAHLWDGNPPMAPPNPRYSHNVQQLKSRILMTATQESRGNIMKISDVKSRVQDLWRGLMNENFIFSFRNTQEVMAMNKLETMYNHWTWELRSHVLGLQNQLINQIQNGKIQTLEASTFEVLVTEKYEVVKQELEKYFNEGPCSKILIQCKANFENKLIVLKEKLISDSKRQANELISFKNQSQERLNKKKTDYEKELLEKSRKLALTVKGKELSEEELHEKFNQLWKKWVCDVSTTLPQVTEPDIDLDSENILWEYFKNKTNVVG-LLTNSAEKF-QINYDKHIKVNKKYNHIPMTLTVFEKEFINMTTDYIVSRFNKIINNMWKQQCGYNPNYFHEILKTIEE-EVKSASTQKRYTFTNTFIIDLCVCLFQRARENFKEMHRAFKRANDPVNYLESKKDDFFTSFKISCQGATSIKTFVDVLWYKLTPAVSTTIWEDMTFKIAGDMRATCPAFNGNRTNLEKHILFSLAEEENFDNYWEYLHNSKSFFRSYIKNHIKRYCSDNGGEKMKTFFEKSLIDIKNTILSAIHESTSVAKDKSSTASEWLDLFCDCLGCNLIFPRRDLISIEHQEIKHTEFLKEAMSAALDLTMKKIEQNYSSKPIEAMVSKIEK---MLSEHLCG-CWKQCPSCGAICTNTIPTHEGDHSVPFHRPQAVNGEEWYETDDFVIDCCTSLVASDCLLVLRDGRNFPFKNYRQAGGDYAMWSITPDTSIQLYWKWFVSHFRSNLEEKYQKKFAGKGKIPNAWAKITKQDVLEDLKKQ---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PWM1-1", "uniprot_id": "A0A8M9PWM1_DANRE", "id": "A0A8M9PWM1-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGLPELAVDPSVGGMDNN---------------------------------------------LNIVLFGSPAAVQFQDDNILLGETQPTVGNVARSRSASLQMKILGRPVS-----------------------------------------------------------------VINLIGFHETVFDLDHIAGQLVNENKIVAFVFVVRLGQLTDADKMGIEWLQRVFGDGVLRFVMILFTYESEEESDSIIDDLKKN-------------------------------LALEQLIEKCGGRYHTCSKIMN-----------------------------------KKSDIGDLMKKIEQLFIDNDQQFYTNEDVQNRICQKAGMEYTTPATK----------------EKRELNVDKHLEDDAITSIEEK--KHLFQRLHLDIRHNFKLKAAKVLLQNTYSLQSHESCSEKDLIQTFLQKLLMMNYRSRYIKTEN-----TIEQHDRPQRNNDLLEDEANVDIFTEMPLFTEEKSQRDPVHPMDIQMAVFYCADSFLKQLMVTKLSQCQYALPLLVPDPFTREIEFPLWAFRQISKSWKIKHAAG---ETSSETQPVWKAETPMVFFFRFG-PVSSSKSQLMNNLIN-EKHNTFFHRNCSGSSETRLLMDGVVEIAWYCPSGKDTDKFTQCVAFCNIHGDAGDHEKQMQILTKLSSVNIVILPRLDENDRSATLIQNLYKDKTPLVCLFAEEKHKVTETRKTKYKIGLKDRNQSDVSEELIKTINKCLSLSSPESSSVFRLENVSKDSGIRVDEEHDGDCRRGKKAAQQMMDLLKGNNLTEIKESFLPCQGKLWHQWCQKNKELHRS--------HEAYVDIKQKQELKKIREMQYALDTGEFMKLFITEMDSK-PLSEKLFFLKWLTVLLDEYTSTDLSALHCKYDEKWSKILKMKEKNDITEQQITTNFRDEHAELDRISEELQAATFGLEHILREIGQIYESCISENKNKQGLPCSFTSLPGLAADMMISGFPLELMDGDAAHVPVVWVTAVLHELIQKLGDQRVFVLSVLGIQSSGKSTMLNAMFGLQFAVSAGRCTRGAFMQLIRVSEEMKMKEKLKFDYILVVDTEGLRALELAERSTRHQDNELATFVVGLGNLTLINVFGENPSELQEILQIVVQAFMRMKKVKLNPSCMFVHQNVSAVTAGEKTMEGRRRLQKTLDEMTKLAAK-DEVCDAECFNDIINFDIQEDVKYFAQLWEGSPPMAPPNPSYCENIQELKQAFFGHASKSDG---LELMHLKKHIINLWEALLNERFVFSFRNCLEISTYRKLETEYSKWSWSLRKTMLDVENKLHNKIENEALHEISESHLHDELSVKIEEVERFMSDFFAKDKNKDILIQWKASFDIKIKELQENIVRETTRKLNEILQQRD-IKRRIDAQRTHHENTLFDKSKELAVKLKDKANDETILKREFDSFWKECVKQITAETPRIKNINVLNDMKQFLRNYKRVCVNDWKNRDIFSVPRYSEYIQIKKSGVTTRHAFGSVKLKFEAETKIRAFVNDIARQADKIIMAYNIEKMGYNKTYIQELADYIKARTVDYEQDCRNCVFKNEFYLDLVMSICERENKLIKDQHRKFREANDPVLYFEKKSKEYYKIFQKYCQGATSAAIFGEIICQKLKEPIQKCVYKDTARDLANEIQTDCESLNGNRSKIEKHILKALAEQEDFDKYIKYIFSPRDHFESFIRDEVNQYITDKFEVSVRPMMKQNIELLKQKIIKAAHRATTSDN-TTKDVQKWLDDFTEQLSDVLIFSVKNFSGVSHDGVDDFNLLKDVIRAELGSVASEIQCKFSTKAFPENLEHEDRPDQVLTNHLCQCCWVQCPFCGATCTNTIENHAGDHSVPFHRVDGLKGSCYDESKCLGADFCTTLVRTSKQFYIG--QWFSCQHYRTAGHVYAQWSITPDFSELPYWKWFVCRFQTELENYFEMKFDNWNVISYDWSQYTKEQAIASLDEYVD-------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*:* * : : : * .. :*: :* ** :. : *: .:: :. * . : .: .* : :: . ::.: * : *..:.. :* : . .:. . *** ..::. *::. *. *::: :. .:: * : .:* :.: .: : : *.::: : :* : *:: : :: *:: .*:*:* *: : ::. *.. * . *: . :. **::* *******::* *:: :: . : ::: :: :. .: .. .. :**:****::::***.: :* :.:*** *::****:**:* . :*** **::*** :**: : . ..* : ..*.:* *.*.* :*:****:** *:. .**:.****:* ** : *:* *:***.*:**.*:. * * :*::* .:**** :* :*: :* .:*:: ::::. *:*. . .::::* :. **:**: ::: ::: : ::*:*:**:::::*** .:*.: *.**. *: .: ::. *: :**:: **:..*: ** :* :* :*:: **.:** **:*** **:*:**::: .: :*: .:. : .:: *: .::*: .: ::. :*:.*:**::::*: * .*. ** : * : *:: . .. : ::: ** *: .*:* *:::**:*****: . .. .** :***:**:*.*:*******::**: **:*::.:: :*:**:*:****:**:*******:***:*****:****:**:**:***::* * .:.*:* *:::*.:******* * ::* . *:**.*:*:**.******:******::*:**** ****:***:**: ***:******. .*. ::**:**:**::.****: :**: :: : *.*:*.** : .* ***:**:*.******* *. *:*:*:. :: * :.. ::: ..* :: :**..*:.*.*:***** *: : **** *..*:*.**. :*.::*:* *:*:* : : . :. :: * : ::. :..:* :. . *:* **.*: *: *:: :: :: :: :* :. : :. :: :::.:*: *:::*::**:.::.* : * .:* .:*.. : :::: *::.: :: * :::* :* . * * .: : *: :.. : .* *. .: * : : : :: .*. .*::*: *: :. .*.. : :** : : :* : :*. * *: ***** *:* *..::: *: ****** * :.: **. .:. ::: .:*.:::: :****:::* *** :***:*.**:* :*: .. .*..:*::.:.:* :: .::.::: .: :* *:.* *.:* : . . .. *** * : *. *:*. ::: .:.*: : . ::**:.: *. . ::: . *:* : : . :: :*::*** ** *** * * ***** * ***** *** :.:.* ::. : : **: * :. : : : *. ::** ** :* ****** * ******.:*:::**: : ** . . :. *:: **::.: .* : ", "identical_positions": 523, "similar_positions": 677, "identity": "21.19%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-619", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VP76-1", "uniprot_id": "AC78C_DROME", "id": "Q9VP76-1", "name": "Adenylyl cyclase 78C", "aln": "MDVELEEEEERICLRTAEEGQLANMDDDKLVSDEVHLRQLSATPSSAFSLQHSRGSDTKEEAPPEGGTMGGKSAAPREEGEPDERVVLRRAVDKGAIALAQIDDLKLEGDDDDEAVVNGEEVDGLGLSNPAAQTTDDEQITVNGTGAAATSSVAADAASSEQDAASTAMATPDMSKIPRLPGDGAQMEDNGSGDLPPSLRASTTSILSNLRKKQQGGPLRGGVAKQTPLRVQSVRIVEAKRAYGPKRRTESCSIFGNSNFEHDLESGNSLASIPGQSQRPLNNEMYSAFKSGNVVKGILCPSLTNSFKQSSLERSYLTYTHRQRQKSLIIVNVVDFVLKIVLAFVWIMRRSELGPIESDDGTSMATAITWSVCCGIANMAICFLGYWRCFANNYLHWAAVCTWVLFNIQGFVGQGVGFADREYLVWYILFVIFVPYAMLPLPLKWCVVGGTITASCHLAVITIIKLQHGEATINPECVLFQIFANFILYTAINVAGMYTKYLTDRGQRLAFIETHKAMEHKKESEKELQRTQKLLDSILPNIVNNQIRSEMYKGTDPTVETQFNKLYVYPMDNVSILFADIKGFTELASKTSAQQLVKILNDLFARFDRIAEDNHCLRVKLLGDCYYCVSQFESDNWKTRPDHAVCSVETGLHMIKAIKDVRLHTHVDLNMRIGIHSGSVMCGVLGNKKWHFDVWSNDVIIANHMESGGIPGRVHISEATLKCLNDAYEVEPGNGGCRDNHLKMLNVKTYLIKRTEPLRPKRRFGTRSSAHLAGSVATAAPPCATPTALPKSISASGSGSIGGVTATGNDGASIDGRSLEYAATIAVPAQQPTQLLQQQQKKNISLNSLPNVVEGVAMDSRRIRNGCGVMGGAGGTGGGGTGPCGMSTVSSPTAMMSAPLEVQLRPRNGACSIQNLAEAIDGKGLIIEDESTTDWIPEIPFKNLNSPEDGLNRADSILVDTKEDHRVSVAVLDEEIDEFIEQNIQINSNKEIRREYLNPWTLKFKDKSQEQKFCQLREDMFRSNMLCVFVIWIFMVLCQVIIIP-RCTRLIICLSVGTVILTFCCVLVMAEEFPGLPRCLKTNSAKLVHQRQRRTLFICGVIVSMCMLSAIGLVLCPSSTYIGTADEHSRFLRMVSPYSNISMTEKEFKLNVYLSATIHHNITISTPASGGPTPLVDITSSGPSDEFVRSTLNALTLNLTPPLPQSHRPYTLTTNGHSVSLSNLSYSDASVMQSSSDVEGQCAHPEYLVFTWVLCLVSLATALKLYYLVKALMALAMVAFYTTLIMMKFGSGDSFSLVELSRLG---MPLGVQMLILLISFLVMVCYHARLVEVTSRLDFIWKEQAERELTNMKSNRALNDTLIKNILPDHVATYYLS-DEHTDELYSKMHNLCGVMFASIPNFQDFYS--EDIDNGKACIRILNEIICDFDELLEEPRFASVEKIKTVGATYMAAAGLNHEHLRLRGETSEDSVCDLVEFAFAMKQKLEEINGDAFNNFQLRVGICSGPLVSGVIGARKPVYDIWGNTVNVASRMDSTGENWRVQVPENTAELLCSRGYTCVKRGEIAVKGKGMMTTFYVHPKGISESQLISPVRMPAGIPLAQTPNLQRQTSHHGSFSAVVFGMLQASKRSTAIAGTPTGTPSPQIRRGHRGSTFSSVRLSQKSTTVNPVRRNTTRVRGRSYRQKKSSSNNSIVTQASSSYMPSFRRIDQIETTISKSHNDAL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E7FC63-1", "uniprot_id": "E7FC63_DANRE", "id": "E7FC63-1", "name": "adenylate cyclase", "aln": "----------------------------------------------------MALNSSEITVPPQVCTIVPPSPNLKRKQ--------------------------------------------LMWQNAVRHIIDQRGMHHEGRAVNSRKIIVTDAYIDD--------------------------------------------INRQIRNKAARGNAGMHKRRSSAARIHPFRERNSTCTRKSTESVTDADFFVS---------------------------------WGSTVRGIFLPALHHKFKSHDLEHLYQQHSSGQRRTSLVVTNVIDILTKLHIIFIYLALAPEMVDSQHGWLAGLLMALGAIICVLVLTCKGLMS-------PDYLRYAGLASWLSQTVQALG--GLVYGLETDQSWYVLFTLFAIYTLLPLPLLWSICMGFLTAALHLFVDTFKNYND-------TAIVRKLLAKGLLYMGMNTAGLFIHYLSDRAQRQAFLETRRCIEGRVKMERENQRQERLVMSILPRFIAMEMIGDMTALDDELLPQQFHKTYFHQYKDVSILFADIKGFTSLSMTMPAQELVRTLNELFGRFDRLAEENHCMRIKILGDCYYCVSGVP----EPQTAHARCCVEMGLAMINTIRYVRKELKRDMDMRIGIHSGSVLCGVLGLQKWQFDVWSWDVDVANMLEAGGIPGRIHISRATLDCLEGVYETEEGRGHERNEFLRKHKIDTFLIRHTP----------------------------------------------------------------------QDDKEPPKVRRTSKDE------------------------------------------------------------------------------------------TTWSAELPFDNIIGMNCILATFTNGSLVHLPNQITPHCAGSREINKRIKQAIEVRSSERMRKEHITPFTLVFKDTHIEGKFSQMRDEMFKSNLACSFLLLLFIMAAQALIPSPQFFPMIIQFLVFLFVYMLVLLVTLAEEFKRSPPYLQHLCCWIHETKSIRNLLTLTAIAINFGVASCNIFWCNG-----------------------------------------------------------------------------------TFEETEKSNKNSEHGKQWPVN------------------ICTHPEFFVLSGVVAMVTCAVFLRLSCLLKLAVLTLVIAVYTYLIEVAFHVLFIRQHQNSQIQRSQYLRRKGISVLLMAMFVVVVLYNSRQLETTSRLDFLWRLQARQEVEDMKELREHNECLLYNILPAHVARHFLERDRNNEDLFSESYERVGVMFASIPGFSDYYEKKELIHQDVECLRLLNEIIADFDELLDEPYFQDIEKIKTIGSCYMAASGLSPEKQ--ECEDEWAHLSTLVLFALAMQETLKEINKRTSNDFWLRVGISHGPVVAGVIGATKPQYDIWGMTVNLASRMDSTGLSGRIQVPEATSRVLAEHGFMLQLRGEIYVKG-------VSERRGAVRTYFVSSREHNS--SYAERNTSRGISLGRNTLAAVVFSLVQARKK-------------EELREANGGFHLKDMA----------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..:: .**: *: *. :.: * .*.. : *:. : :* .. : . :.:** .: * ::*:* * :.:. *::..* ::. : ... . ...:* . *..*:**: *:* :.**. .**: * :: **:.**::.**:*:: *: : *::: .*: : . :.: *: :* : . : :**::*.:.:*: .:*.: *: :. . **:**.:*. *::***** *.: * :**: ** * *: : :. .:: :::*: :** .:*.**:: :**:**.** **:**::.:* : : *:* ** ::*: ****.:: :: .:* * : **:* *.: .:************.*: . .**:**: **:**.****:**:***:*:*:********* . :.:. ** *.** ** **::*: ** . : *::**********:***** :**:***** ** :** :*:******:***.***.**:..**.* *.* *::.*: ::.*:**::* ::*.:: : .:.: * * .*:**.*: . : * . : :: .. .. ..**:: *:* *::.*.:.:*:*::.*:** ***. * **.*:*::**:**: * *:: :*:: .*.:* . : :** : * .: : ::.:**** * *: .. : . :. *.*: .*. ::: .:. * . .: ::.:. . : :*:. .:. *:***::*:: *:.:*: *. *:* *:* : ::*.** ** : * . : . : ::*: *:*:* *::* :*.******:*: **.:*: :**. * *: *: **** *** ::*. *.:.::*:*: :: ********.*.*:*. * *.:. *:*:*****.******:** * .:*****:*: ****:**. *: . * . :. ** **:**::.*:*** : *:* *****. **:*:***** ** ***** ***:******** . *:**** *:.:*..:*: **** *** . :* .: ::*. . : . *: . : : :.:::****.::** *: ::*..: * :..: ", "identical_positions": 417, "similar_positions": 434, "identity": "24.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-620", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZNQ0-1", "uniprot_id": "D3ZNQ0_RAT", "id": "D3ZNQ0-1", "name": "", "aln": "MSWTCPRCQQPVYFAEKVSSVGKHWHRFCLKCERCHSILSPGGHAEHNGRPYCHKPCYGALFGPRGVNIGGVGCYLYNPPSPPPASSISLSPSNFSPPRPRTG----LPRAKKSPPYLKTFTGETSLCPGCGDPVYFAEKVMSLGRNWHRPCLRCQRCRKTLTAGSHAEHDGMPYCHIPCYGYLFGPKGVNIGD---VGCYIYDPVDIRPK----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6Q6R3-3", "uniprot_id": "CRIP3_MOUSE", "id": "Q6Q6R3-3", "name": "Cysteine-rich protein 3", "aln": "MSWTCPRCQQPVYFAEKVSSLGKNWHRFCLKCERCHSILSPGGHAEHNGRPYCHKPCYGALFGPRGVNIGGVGCYLYNLPTPPPASRISLSPSNFSPPRPRTG----LSRAKKGPPYLKTFTGETSLCPGCGDPVFFAEKVMSLGRNWHRPCLRCQRCRKTLTAGSHAEHDGMPYCHIPCYGYLFGPKGVNIGD---VGCYIYDPVDIRSK----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6Q6R5-1", "uniprot_id": "CRIP3_HUMAN", "id": "Q6Q6R5-1", "name": "Cysteine-rich protein 3", "aln": "MSWTCPRCQQPVFFAEKVSSLGKNWHRFCLKCERCHSILSPGGHAEHNGRPYCHKPCYGALFGPRGVNIGGVGSYLYNPPTPSPGCTTPLSPSSFSPPRPRTG----LPQGKKSPPHMKTFTGETSLCPGCGEPVYFAEKVMSLGRNWHRPCLRCQRCHKTLTAGSHAEHDGVPYCHVPCYGYLFGPKGGQPHPRHWDGMYMPEVWHVHGLWVCVDNFPCG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P9H3-1", "uniprot_id": "A0A8M9P9H3_DANRE", "id": "A0A8M9P9H3-1", "name": "", "aln": "MTSICPRCDKTVFFAEKVSSLGKNWHRFCLKCERCSKILSPGGHAEHDGLPYCHKPCYGTLFGPKGVNIGGAGSYIYDTPPQTPVNKTCNSPSEGSPTTPWTTSQINFNQPKAATAPARMFAGETYLCPGCGKAVYFAEKVMSLGRNWHRPCLRCVRCKKTLTPGGHAEHEGSPYCHVPCYGYLFGPKGVNIGR---VGCYIYENENAENERPSEH-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ****::.*:*******:**:*********** .**********:* *********:****:******.*.*:*: *. .* ***. **. * * : : * ... : *:*** ******..*:******************* **:****.*.****:* ****:*********** : * *: : . . ", "identical_positions": 128, "similar_positions": 39, "identity": "57.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-626", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35345-1", "uniprot_id": "IMA7_MOUSE", "id": "O35345-1", "name": "Importin subunit alpha-7", "aln": "METMASPGKDNYRMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTTG-ESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPGVVDRFVEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSLCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSSKESIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQESKRSGSGVNPYCGLIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEDDDSSLAPQVDETQQQFIFQQPEAPMEGFQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60684-1", "uniprot_id": "IMA7_HUMAN", "id": "O60684-1", "name": "Importin subunit alpha-7", "aln": "METMASPGKDNYRMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAAMFDSLLMDSYVSSTTG-ESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFEDVQEQAVWALGNIAGDSSVCRDYVLNCSILNPLLTLLTKSTRLTMTRNAVWALSNLCRGKNPPPEFAKVSPCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHNDYKVASPALRAVGNIVTGDDIQTQVILNCSALPCLLHLLSSPKESIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVSLGCIKPLCDLLTVMDSKIVQVALNGLENILRLGEQEGKRSGSGVNPYCGLIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEDDDSSLAPQVDETQQQFIFQQPEAPMEGFQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F7U9-1", "uniprot_id": "E7F7U9_DANRE", "id": "E7F7U9-1", "name": "Importin subunit alpha", "aln": "MEPSGSPAKDNFRMNRYKNKALNLEEMRRRREEEGIQLRKQKREQQLFKRRNVELLGEEGGMFDSPLMDSYVSSTTAPDGVITRDMVEMLFSEDPELQLVTTQRFRKLLSKEPNPPIDEVISTPGVVNRFVEFLQKSTNCTLQFEAAWALTNIASGTSQQTKFVIEAGAVPVFIELLNSDFEDVQEQAVWALGNIAGDSAVCRDYVLNCNILPPLLVLLTKSTRLTMTRNAVWALSNLCRGKSPPPDFEKVSPCLPVLSRLLFSSDSDLLADACWALSYLSDGPNEKIQAVIDSGVCRRLVELLMHSDYKVASPSLRAVGNIVTGDDIQTQVVLNCSALPCLLHLLSSAKESIRKEACWTISNITAGNRAQIQAVIDANIFPVLIEILQKAEFRTRKEAAWAITNATSGGTPEQIRYLVNLGCIKPLCDLLTVMDSKIVLVALNGLENILRLGEQEAKQNGSGLNPYCSLIEEAYGLDKIEFLQSHENQEIYQKAFDLIEHYFGVEEEDANLVPQVDENQQQFLFPQQEAPMEGFQL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. .**.***:**: ***:*** *******************************:.**..**** **********. :.****:*******:*.:***.***:*********.*******.** **:******::. ************************:********:***************************::********.** ***.*************************.***:* *********************************************************.*******:*****************:***************.**********************************************************************.******************* ****************.*:.***:****.*************************************::*:.*.*****.****:* * *********", "identical_positions": 475, "similar_positions": 50, "identity": "88.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-632", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q64GA5-1", "uniprot_id": "PA24C_MOUSE", "id": "Q64GA5-1", "name": "Cytosolic phospholipase A2 gamma", "aln": "--------------------------------------------------MELSSGVCPATRLQEAEKAAVHKRSPKVLEALRKLNIQA--DQAPVIAVLGSGGGLRAHIACLGVLSELKELGLLDAVTYLAGVSGSTWALSSLYTK---NGNMEGIEEELKHRYEKNEWDFHESLEKAIQASK-RENYSLTDFWAYLIVSRQIRELQDSNLSSLKKQVEEGVLPYPIFAAIDEDLLADWRERKTQNSWFEFTPHHAGYPALGAYVPITEFGSRFENGKLVKSEPERDLTFLRGLWGSAFADIKEIKNYILNYFRNPFGKLK---FIEG---PVTYSEAPRMNVDAMLLDLVMAYFTDMNDPSIKDKLCALQQALGTETDEFGIEMAEIIQNWNETSAEKKEQFLDHLLDRFKKTQEDTTT--YSLMNWNTGLVWDRCVFVNETRKCVSKWQWGTVYNFLYKHGK-IADETMCSRELLHLVDAGFAINTPYPLVLPPVRETHLILSFDFSAGDPLETIRATADYCQRHEIPFPEVSEDQLKEWAKAPASCYVLR----GETGPVVMHFTLFNKDNCGDDIETWRKKYGTVKLSDSYTPDLVRDLLRVSKENVKKNKINILSEMRKVAGNPGNIPRVNKEACLGDRVKDPQGSQ-TVEFKKSHNISKD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LY61-1", "uniprot_id": "F1LY61_RAT", "id": "F1LY61-1", "name": "", "aln": "-----------------------------------------MSCAESPKSQHKRSGVYFATGLQEEEKGAVHKRSFKVLEGLKKLNIQA--DQAPVIAVLGSGGGLRAHIACLGMLSAMKELGLLDAVTYLAGVSGSTWALSSFYTK---NGNMQGMEEELKHRYEKNEWHFDESLDKAIQASR-RENYSLTDFWAYLVVSRQTRELHDSNLSGFKKQVEEGVLPYPIFAAIDDDLQDDWREKKVQNSWFEFTPHHAGYPALRAYVPITEFGSRFENGKLVRPEPERDLTFLRGLWGSALADIKEDKAFIMDYFKDMHEKLKKKYLHRGGAKTVTYSNAEQMDVDEMFLDLLMAYAIDQDDPSIKDKLCVMQQALGPETGEFGKEMAEIIQNWNEISPEKKEQFLDYLLDYLKKPQEPITYSLRSIGNWIGDLFYDALTFVRKTGMCLWEWQWGTVYNFLYKHGN-IADETMCNREFLHLVDAGLAINTPYPLILTPVREAHLILSFDFSAGDPFETIRVTADYCHQHKIPFPEVSEDQLKELAKSPKSCYILR----GETGPVVMHFPLFNKDNCGDDIETWRKKYKTMKLSDSYTPSMVTDLLRVSKENVQKNKEKIVNEMREVTG------------------HYLQRTT-PCALSKIHH----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UP65-1", "uniprot_id": "PA24C_HUMAN", "id": "Q9UP65-1", "name": "Cytosolic phospholipase A2 gamma", "aln": "---------------------------------------------------MGSSEVSIIPGLQKEEKAAVERRRLHVLKALKKLRIEA--DEAPVVAVLGSGGGLRAHIACLGVLSEMKEQGLLDAVTYLAGVSGSTWAISSLYTN---DGDMEALEADLKHRFTRQEWDLAKSLQKTIQAAR-SENYSLTDFWAYMVISKQTRELPESHLSNMKKPVEEGTLPYPIFAAIDNDLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRGLWGSALGNTEVIREYIFDQLRNLTLKG----LWRR-----AVANAKSIG------HLIFARLLRLQESSQGEHPPPEDEGGEPE----HTWLTEMLENWTRTSLEKQE-----------QPHEDPER---------KGSLSNLMDFVKKTGICASKWEWGTTHNFLYKHGG-IRDKIMSSRKHLHLVDAGLAINTPFPLVLPPTREVHLILSFDFSAGDPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPASCYILK----GETGPVVMHFPLFNIDACGGDIEAWSDTYDTFKLADTYTLDVVVLLLALAKKNVRENKKKILRELMNVAG-----------------LYYPKDSARSCCLA--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JND6-1", "uniprot_id": "A0AC58JND6_DANRE", "id": "A0AC58JND6-1", "name": "", "aln": "MKLFSSVADSSKTLLPVQNKQTRNHLGFVAYSCCTETVSNCDPKTKMSASNVQESEVRIAHSLNMKEAACVKKRRSEIWSSLKTLGINCSQDKVPNIALLGSGGGQRAMVGLLGSLDQLDKTGLLSCLLYLSGVSGSTWCMASLYQEPDWSTKLQAVKEKIVRRISGPPVSWSDAYAKLKKYYREKEYFSLTDVWATMVVTTYVKEIDERTFTDWLGQSKN--NPFPIYTLIDKECKQSGDG----DPWFEISPCEAGYSLTGAFVKTPSFGSQFVNGRKTTSQPEMDMLLLQALCGSALADGEENKKFLWSKIKGLFRHAS-DQMIEQMEQDPILQQVDTCSDVLEELAAINICLLDGEDPTTLDHS--IRKSLKDLAGHDPQLISPDKSSEDEYTLEVCG-----------LLEELQVK--------LNISWPVDLKMWIRIFVCMAKWTWGRNYDFLYNMRDPAVPAALLKSKTRDYEDAGLLLNSPYFSVLRTERKIDIIISLDFSEGDPFQTVKEAAEACRKLKIPFPPIN--LLAEDIKNPKDFYVFKNTSTDKKAPTVIHIPLFNVINCGDKLGQYRKNYTTFQG--AYSAEKIIDLMNVAGKNISNNKQELINVINEVIRKK-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * *: * ..*.:* .: ..*:.* *:. *:.* :*:****** ** :. ** *. :.: ***..: **:*******.::*:* : . .::.:: .: :* .: * : : * :****.** :::: :*: : ::. :: *:**:: **.: . :.***::* .**:. *:* . ***:* :*: . ..** *: :*:.* ***:.: : : :: . ::. : : . :. . : ::.: :: :. :: .. . : * .* : . * :* ** ::***: : . : . ***: :*:*: :* . *: .:*:*:*** ***::*:: ::: *:: :**** :. * * * . *::: .:..*.*:*:.*** **..: : ..* *.: :*: . : *: :: :*: :** ::: : :* ", "identical_positions": 123, "similar_positions": 186, "identity": "18.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-633", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZQ03-1", "uniprot_id": "FNBP4_MOUSE", "id": "Q6ZQ03-1", "name": "Formin-binding protein 4", "aln": "MMGKKSRAVPGRRPILQLSPPGPRSSTPGRDPDPDPDPEADSTAAATSQSAPAAATAAAATSPAVPASAAPEDSPSEDEQEVVVEVPNVVQNPPTPVMTTRPTAVKATGGLCLLGAYADSDDDESDVSEKTAQSKEANGNQATDIDSTLANFLAEIDAIT-APQPAAPVVASAPPPTPPRPEPKEAATPALSPTASNGSDTAQTPGWHYDTQCSLAGVEIEMGDWQEVWDENTGCYYYWNTQTNEVTWELPQYLATQVQGLQHYQPSSVTGTEAAFVVNTDMYTKERTTAASSSKSGPVITKREVKK-EVNEGIQALSNSEEERKGVAAALLAPLLPEGVKEEEERWRRKVICKEADPVSETKETSTASEETGPSIKPPEVMMDGTEDPSQEELCSVVQSGESEEEEEEEEQDTLELELALERKKAELRALEEGDGSVSGSSPRSDISQPASQDGVRRIMSKRGKWK-MFVRATSPESTSRSSSKTGRDSPENGETAIGAEDSEKIDEISDKETEVEESSEKIKVQLAPKVEEEQDLKFQIGELANTLTSKFEFLGINRQSISNFHMLLLQTETRIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEE-SQTKEVRDESLPKLTVKDKTCTDPNSTESSENPTGSLCKESFSGQVSSS-LMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPPPPPLEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSTQTTAVTSQSLVDSTASSPPSNKAVKRKAPEMSTSVVQRSATIGSSPVLYSQSAIAAGHQAVGMAHQAVGMAHQAVSASHAAAAGVGHQARGMSLQSNYLGLAAAPALMSYAECSVPIGVTTPSLQPAQARGTMAAPAVVEPPPPPPPPPTPTPPPPPPAPKVPPPEKTRKGKKDKAKKSKTKMPSLVKKWQSIQRELDEEDNSSSSEEDRESTAQKRIEEWKQQQLVSGLAERNANFEALPEDWRAR-LKRRKMAPST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N3X1-1", "uniprot_id": "FNBP4_HUMAN", "id": "Q8N3X1-1", "name": "Formin-binding protein 4", "aln": "-MGKKSRAVPGRRPILQLSPPGPRGSTPGRDPEPEPDTEPDSTAAVPSQPAPSAATT---TTTAVTAAAASDDSPSEDEQEAVQEVPRVVQNPPKPVMTTRPTAVKATGGLCLLGAYADSDDDDNDVSEKLAQSKETNGNQSTDIDSTLANFLAEIDAIT-APQPAAPVGASAPPPTPPRPEPKEAATSTLSSSTSNGTDSTQTSGWQYDTQCSLAGVGIEMGDWQEVWDENTGCYYYWNTQTNEVTWELPQYLATQVQGLQHYQPSSVPGAETSFVVNTDIYSKEKTISVSSSKSGPVIAKREVKK-EVNEGIQALSNSEEEKKGVAASLLAPLLPEGIKEEEERWRRKVICKE-EPVSEVKETSTTVEEATTIVKPQEIMLDNIEDPSQEDLCSVVQSGESEEEEE---QDTLELELVLERKKAELRALEEGDGSVSGSSPRSDISQPASQDGMRRLMSKRGKWK-MFVRATSPESTSRSSSKTGRDTPENGETAIGAENSEKIDENSDKEMEVEESPEKIKVQTTPKVEEEQDLKFQIGELANTLTSKFEFLGINRQSISNFHVLLLQTETRIADWREGALNGNYLKRKLQDAAEQLKQYEINATPKGWSCHWDRDHRRYFYVNEQSGESQWEFPDGEEEEEESQAQENRDETLAKQTLKDKTGTDSNSTESSETSTGSLCKESFSGQVSSSSLMPLTPFWTLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPP---AEDGEIQEVEMEDEGSEEPPAPGTEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSPVLYSQSAIATGHQAAGIGNQATGIGHQTIPVS-LPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARGAVPTATIIEPPPPPPPP----PPPPPPAPKMPPPEKTKKGRKDKAKKSKTKMPSLVKKWQSIQRELDEEDNSSSSEEDRESTAQKRIEEWKQQQLVSGMAERNANFEALPEDWRAR-LKRRKMAPNT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QGN0-1", "uniprot_id": "F1QGN0_DANRE", "id": "F1QGN0-1", "name": "", "aln": "-MGKKTRAGTGRRTILQLSPPGPNRSATG-------------------------------TAREDGAASGSEDETDGNTDGQREANVNVVMKTP---------AVKATQGLSLLGAYEDSEDED-----AVENASKAKHNQSGDIDSTLANFMAEIDAITTQPTDESGTEPSAPVPTPPRPEPK------TDPQAQNGP----AQEFQYNTQYSLAGAGLEMGDWQEVWDENTGCYYYWNTQTNEVAWELPHYLADQMQNLHYSGSSSVNGNGVAHSS----YPEPQSTAVAP------AAKRELKKKDVIESVVALTSEEEERRGVAATLLAPLIPEEVKEAEEKWRKKTLGME-----ETPEAAPEQEKDTIPFLDSPAIRDTESQNNQRSRNQSAESSDQEEEEQE--EDTMELELALERKKAELRALEEGDASAGGSSPCS----EASQDGPRTLLLKKNKWKTAFLRAPSPDSSSRGSDKAGWATPEQSDTAH-SKPAEKQGEDDENEKPVSKALQ----------KEEEDLKFQIGELANTLTSKMEFLGIDKKAISNFQLLLLQTETRIADWREGALNGSYLRRRLQEAAEHIKHYELNATPKGWSCHWDREHRRYFYMNERTSASQWEFPVGGEEEE------------AKPPLPSATAHGDSSQPSAETTG------VVTGDVQSYWMVPPPP-QPPLPPLPPEHPPPPPTEQPPPPPPPPESPPPPPPPPLE----DDGEIEEVEMEDEESE-PPAPGTEEFKAAEAAALGLAARAQ----------------KRKA--LGSVPLPSMATIGSSPILYTQTIATPAPLLVG---------------------------------SAYWGMTAAIAPPLPTESIVPP---MPALPP-------------QPPPPVSQP----PPPLEPISKVLT-DKTKKLKKEKAKKSKTKMPSLVKKWQSIQKELDEEEKSSSSDEDRDQLNNRRIEEWKQQQLSTGKAGKNANFEALPDDWRERLLKKRKMMQSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****:** .***.*********. *:.* *: *::..:*... : : .** :.* ***** **.***** **:*:: ::.::: **: *********:******* * : . .*** ********* .. :.**. : ::*:** ****. :**************************:****:*** *:*.*:: .*** * .:. *.: :: :.:. :***:** :* *.: **:..***::****:*****:** :** **:**:*.: * *. *::. *: . : * .: .*.. . .:*.:.****: :**:****.***************.*..**** * ***** * :: *:.*** *:**.**:*:**.*.*:* :**:.:** :: :** .* .::* *.:: : :**:****************:*****::::****::*******************.**:*:**:***::*:**:*************:******:**::. ****** * **** .* .: . * . .* *:*.. .:*:*.* ::* .* . * . * ** * * ****************** :****:******* ** ******** .. :.:: .. :* **** :.: : *******:**:*: :.. .* * * *::** * :*. ** *:* * :**** . * *** * .*: . :**:* :*:********************:*****::****:***:. ::********** :* * :********:*** * **:*** .:", "identical_positions": 467, "similar_positions": 222, "identity": "45.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-634", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AD66-1", "uniprot_id": "D4AD66_RAT", "id": "D4AD66-1", "name": "", "aln": "MPMSSRGRDLHPGHHHFGPCSPLTQFWPGP-EPQSVKGLYYRRARKVSTL-DASPEANLKEILVNVGGQRYLLPWSTLDAFPLSRLSRLRLCRSYEEITQLCDDYDENSQEFFFDRNPSAFGVIVSFLAAGKLVLLREMCALSFREELSYWGIEEANLERCCLRKLLKKLEEAAELRREE-AAQRQQQRQACHSEVQASRWARSMNQLREMVEDPQSGLPGKVFACLSVLFVATTAVSLCVSTMPDFRAEEDKGECARKCYYIFVVETICVAWFSLEFCLRFVQAPNKCQFFRGPLNVIDILAISPYYVSLAVSDE--SPEAGERPSGSS--YLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCAREFGLLLLFLGVAVTLFSPLVYVAENESGR-----VLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKREQEQVQ--ARLRRLQNN----------------NSASERELLSDVDDLAPEDLTSPGRYM---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80XM3-1", "uniprot_id": "KCNG4_MOUSE", "id": "Q80XM3-1", "name": "Voltage-gated potassium channel regulatory subunit KCNG4", "aln": "MPMSSRDRDLHPGHHHFGSCSPLSQLWPGP-EPKSVKGLYYSRARKVGNQ-DASPEANLKEILVNVGGQRYLLPWSTLDAFPLSRLSRLRLCRSHEEITQLCDDYDEDSQEFFFDRNPSAFGVIVSFLAAGKLVLLREMCALSFREELSYWGIEETNLERCCLRKLLKKLEEAAELRREE-AAQRQQQRQACHSEVQASRWARSMNQLREMVEDPQSGLPGKVFACLSVLFVATTAVSLCVSTMPDFRAEEGKGECTRKCYYIFVVESICVAWFSLEFCLRFVQAPNKCQFFRGPLNVIDILAISPYYVSLAVSDE--SPEAGERPSSSS--YLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCAREFGLLMLFLAVAVTLFSPLVYVAENESGR-----VLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKREQEQVQ--ARLRRLQNT----------------NSASERELLSDVDDLVPEGLTSPGRYM---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDN1-1", "uniprot_id": "KCNG4_HUMAN", "id": "Q8TDN1-1", "name": "Voltage-gated potassium channel regulatory subunit KCNG4", "aln": "MPMPSRDGGLHPRHHHYGSHSPWSQLLSSPMETPSIKGLYYRRVRKVGAL-DASPVDLKKEILINVGGRRYLLPWSTLDRFPLSRLSKLRLCRSYEEIVQLCDDYDEDSQEFFFDRSPSAFGVIVSFLAAGKLVLLQEMCALSFQEELAYWGIEEAHLERCCLRKLLRKLEELEELAKLHREDVLRQQRETRRPASHSSRWGLCMNRLREMVENPQSGLPGKVFACLSILFVATTAVSLCVSTMPDLRAEEDQGECSRKCYYIFIVETICVAWFSLEFCLRFVQAQDKCQFFQGPLNIIDILAISPYYVSLAVSEE--PPEDGERPSGSS--YLEKVGLVLRVLRALRILYVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLAVAITLFSPLVYVAEKESGR-----VLEFTSIPASYWWAIISMTTVGYGDMVPRSVPGQMVALSSILSGILIMAFPATSIFHTFSHSYLELKKEQEQLQ--ARLRHLQNTGPASECELLDP-----HVASEHELMNDVNDLILEGPALPIMHM---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B1J1-1", "uniprot_id": "A0A8M3B1J1_DANRE", "id": "A0A8M3B1J1-1", "name": "", "aln": "MPIISNANHDFSNLSVSTDDSSLDLFFTEIPETETIKGVYFQRAQRLCGISTLKDVDHSKLALINVGGDRYTFPWSTLDEFPLSRLGQLRHCSSPDDIAQLCDDYDEARREFFFDRSSVAFRVILNFLAAGKLRLLRQVCAVSLSDELTYWGIDPVHMERCCRRKLLSRVEDVAEKKKKE-DERKQKRHALQRPLAQDKGFIRLMNRLQEIVENPHSGWAGKLFACFSVVMIAVTVISLCISTLPDH---ENRGECTEKCRNIFIVETVCVAWFSMEFLLRFLQAESKMQFLRNPLNVIDVIAILPYYISLVVDSEDTSDEAELNGAGTSRGYLDKLGLILRVMRALRILYVMRLARHSLGLQTLGLTMQRSMREFGLLLLFLCVAVALFSPLVHLAEKEFSKGKATGPNSFSSIPASYWWAIISMTTVGYGDMVPYSIPGQVVAFSSILSGILIMAFPATSIFHVFSRSYHELKREQEMIYKEERVAILDATAKEDAQRLLKRDSFSWAIANRNSLRKDNGTAAIQPTLTAAACCKDI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: *. .. *. : . *. ::**:*: *.::: . * *:**** ** :****** ******.:** * * ::*.******** :******.. ** **:.******* **:::**:*: :**:****: .::**** **** ::*: * : . :::: :. : . : **:*:*:**:*:** .**:***:*::::*.*.:***:**:** *.:***:.** **:**::******:** ***:** .* **::.***:**::** ***:**.*..* . * . :.:* **:*:**:***:************************::*. ******:*** **::******::**:* .: .*:*********************** *:***:**:*******************.**:** ***:*** : *: *: . *....* .* . : . ", "identical_positions": 263, "similar_positions": 131, "identity": "48.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-635", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2TAY7-1", "uniprot_id": "SMU1_HUMAN", "id": "Q2TAY7-1", "name": "WD40 repeat-containing protein SMU1", "aln": "MSIEIESSDVIRLIMQYLKENSLHRALATLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQTQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQ--------------------------ALKWQQHQGLLPPGMTIDLFRGKAAVKDVEEEKFPTQLSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIAHHPHQNLIATYSEDGLLKLWKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UKJ7-1", "uniprot_id": "SMU1_MOUSE", "id": "Q3UKJ7-1", "name": "WD40 repeat-containing protein SMU1", "aln": "MSIEIESSDVIRLIMQYLKENSLHRALATLQEETTVSLNTVDSIESFVADINSGHWDTVLQAIQSLKLPDKTLIDLYEQVVLELIELRELGAARSLLRQTDPMIMLKQTQPERYIHLENLLARSYFDPREAYPDGSSKEKRRAAIAQALAGEVSVVPPSRLMALLGQ--------------------------ALKWQQHQGLLPPGMTIDLFRGKAAVKDVEEEKFPTQLSRHIKFGQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMCFSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEFRGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVILLPKNPEHFVVCNRSNTVVIMNMQGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGEDFVLYCFSTVTGKLERTLTVHEKDVIGIAHHPHQNLIATYSEDGLLKLWKP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FFQ0-1", "uniprot_id": "E7FFQ0_DANRE", "id": "E7FFQ0-1", "name": "WD40 repeat-containing protein SMU1", "aln": "MDLEVESADVIRLIMQYLKENNLHRTLAMLQEETTVSLHTVDSIDSFISDINNGQWDIVLLAIQYLKLPDKLLIDLYEQIVLELIELGELGAAQCLLKQTDPMIMLKHTQPERYSRMETLLTHPYFDSQKAYPVGSSKEKRRLAIAQAFAGEVCLVPPSRLMGLLGQGRICEGALYRLQETKALRQFGSLAMLSLKWQQHQGLLPPGMSLELFRGKGALKDMEEERFPTQLSRLIKFGPKSHVECARFSPDGQYLITGSVDGFIEVWNFTTGKICKDLKYQAQDNFMMMDEAVLCLAVSHDSHVIASGAQDGKIQVWRILNGTCLNRLERAHSKAVTSVCFNRDSTQLLSSSFDQTIRIHGLKSGKCLKEFRGHTAHVNDVIYSHDGQHVISASADGTVKVWTVKTMDCTHTIKTPDIPEGTDITVNNVVLVPKTPEHFVVSNRTNTVVVTNIHGQVMRSFCSGVREGADFVCCTLSPRGEWIYCVGEDYVLYCFSTITGKLERTLTVHEKDVIGIAHHPHQNLIATYSEDGLLKLWKP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:*:**:*************.***:** *********:*****:**::***.*:** ** *** ****** *******:******* *****:.**:*********:****** ::*.**::.***.::*** ******** *****:****.:*******.**** :**************:::*****.*:**:***:******* **** ****************:****************** ***************:****:..*:*:.::*:*******:**:* .* **.*:******.**.:.*.:**:*:**:*************** *******::.**:. :::**:::****:*****:*.:** :*::*:*: . . *******.*:*:**.******.**:****: *::**::***.** ***.*****:**************:*******:*****************************************", "identical_positions": 390, "similar_positions": 101, "identity": "72.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-639", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7Z5Q1-2", "uniprot_id": "CPEB2_HUMAN", "id": "Q7Z5Q1-2", "name": "Cytoplasmic polyadenylation element-binding protein 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPPPSPDSENGFYPGLPSSMNPAFFPSFSPVSPHGCTGLSVPTSGGGGGG-FGGPFSATAVPPPPPPAMNIPQQQPPPPAAPQQPQSRRSPVSPQLQQQHQAAAAAFLQQRNSYNHHQPLLKQSP---WSNHQSSGWGTGSMSWGAMHGRDHRRTGNMGIPGTMNQISPLKKPFSGNVIAPPKFTRSTPSLTPKSWIEDNVFRTDNNSNTLLPLQVRSSLQLPAWGSDSLQDSWCTAAGTSRIDQDRSRMYDSLNMHSLENSLIDIMR-AEHDPLKGRLSYPHPGTDNLLMLN----------------------GRSSLFPIDDGLLDDGHSDQ--VGVLNSPTCYSAHQNGERIERFSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGDIDKRVEVKPYVLDDQMCDECQGARCGGKFAPFFCANVTCLQYYCEFCWANIHSRAGREFHKPLVKEGADRPRQIHFRWN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LST5-1", "uniprot_id": "A0ABK0LST5_RAT", "id": "A0ABK0LST5-1", "name": "", "aln": "MRDFGFGVLHTALLRSGSPRSSPGGSAYRPFAAGPSATPFGPLSPPPLPVTGFSEAASPFAIPSGGGAASSAAASSSSPLVAHQQAVQDELLLGLTQQPARPLSGAAAAEQLPSHHPGGGTNAGVTHLLPSQDFKPSLHHPSSSSASSCCCCRTSSPQDFSKRQQQQLSSQKRKELSPPHRPHPPDAKPTPPPLHCPGRFSPPPPTPPPPPGPLLQSAPLAQRPQPFSLPHTQHLPPQDFAPRQRPADLPQLPQLPPSPPAAPRRRHGGAGSPRQTPVAGEGSAAEPPNAGLPPS--TPPVNPAPGSMESPNHPLLNSPSTLLPGAALGTSAFSSLQSPDLPHPGGGGGGGPPGGGGGGGSASPPPLPGFGTPWSVQTASPPPPQPPPAPQQQPSQQQQPPQQPPQPQPPGSSAATPGGGGGAGGSLSAMPPPSPDSENGFYPGLPSSMNPAFFPSFSPVSPHGCAGLSVPAGGGGGGGGFGGPFSAPAVPAP--PAMNLPQQQPPP-AAPQQPQSRRSPVSPQLQQQHQAAAAAFLQQRNSYNHHQPLLKQSP---WSNHQSSGWGTASMSWGAMHGRDHRRSGNMGIPGTMNQISPLKKPFSGNVIAPPKFTRSTPSLTPKSWIEDNVFRTDNNSNTLLPLQVRSSLQLPAWGSDSLQDSWCTAAGTSRIDQDRSRMYDSLNMHSLENSLIDIMR-AEHDPLKGRLSYPHPGTDNLLMLNGWVPGAELKSCGLHARSYGRRRGRSSLFPIDDSLLDDGHSDQ--VGVLNSPTCYSAHQNGERIERFSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGDIDKRVEVKPYVLDDQMCDECQGARCGGKFAPFFCANVTCLQYYCEFCWANIHSRAGREFHKPLVKEGADRPRQIHFRWN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q812E0-1", "uniprot_id": "CPEB2_MOUSE", "id": "Q812E0-1", "name": "Cytoplasmic polyadenylation element-binding protein 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNLPQQQPPA-AAPQQPQSRRSPVSPQLQQQHQAAAAAFLQQRNSYNHHQPLLKQSP---WSNHQNSGWGTASMSWGAMHGRDHRRSGNMGIPGTMNQISPLKKPFSGNVIAPPKFTRSTPSLTPKSWIEDNVFRTDNNSNTLLPLQVRSSLQLPAWGSDSLQDSWCTAAGTSRIDQDRSRMYDSLNMHSLENSLIDIMR-AEHDPLKGRLSYPHPGTDNLLMLN----------------------GRSSLFPIDDSLLDDGHSDQ--VGVLNSPTCYSAHQNGERIERFSRKVFVGGLPPDIDEDEITASFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQEESSVQALIDACIEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGDIDKRVEVKPYVLDDQMCDECQGARCGGKFAPFFCANVTCLQYYCEFCWANIHSRAGREFHKPLVKEGADRPRQIHFRWN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1RRV8-1", "uniprot_id": "A0A8M1RRV8_DANRE", "id": "A0A8M1RRV8-1", "name": "", "aln": "MGDYSFGLLQTAN-TNTAIISGPALFGGDAFTPYRSASPVRPSSSPR----------------------------VSPLFPSHQRNMQDE--------PAGLTASQSSSEQ-------------------------------SSRFSAAGHAQTAGDLQHDRNIHQQADP--------------------------------------------------------------------------------------------------------QPPYSSSSSSSSSSSTGLDTD--APSSK-VNIQMESPSAHHINNGTG---ANNMLAGAFPEMQN----------------AGGGGGGSASPTLPAFGTPWSVQTSSPPPPVSNSAN-------------------------------------AINPIPATTEPDTYYPGIPSSINPGFFQSFSAN--------PCPVQG------FSSPFS--------------PQINVPP-----QPQSRRSPVSPQIPPQQQ---GAFLQHRNNYNHHQPMMKQSP---WGSHQGSGWNSGGMSWG----RDHRRGGGMGVPGSINQISPMKKPFSSNVIAPPKFPRSAGSLGPKSWIEENMFRTDNNSNTLLPLQ------------------------------DRSRMYDSLNMHSLESSLIDIMR-AEQDPLKGHVGCPHPGADGLLMLN--------------ARSYGRRRGRSSLFPIDDGLLDDGHGNQGVPGVLGSPQCY-PHQNGERIERFSRKVFVGGLPPDIDEDEITSSFRRFGHLVVDWPHKAESKSYFPPKGYAFLLFQEETSVQALIEACLEEDGKLYLCVSSPTIKDKPVQIRPWNLSDSDFVMDGSQPLDPRKTIFVGGVPRPLRAVELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGDIDKRVEVKPYVLDDQLCDECQGARCGGKFAPFFCANVTCLQYYCEFCWANIHSRAGREFHKPLVKEGADRPRQIHFRWN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSR3-1", "uniprot_id": "ORB2_DROME", "id": "Q9VSR3-1", "name": "Translational regulator orb2", "aln": "--MDSLKLPKANSATSSASGSNSNLSGSTSASASAATSPTSSGTAVG------------------------------GILSGAPKS------------PPGLGSSTP----------------------------------ISVRFNANEESLDDILQSFHHSKHSPSGG----------------------------------------------------------------------------------------------------------ASGGGDASPTSNLLGMKNNGLGLVVGNCDSLSSSPSQPQMHAGSASLFGNDEVSLRNNFMQA-----------------GGFFNRKSCGGLPNLNLNKPPQLHQQQHQQQHQQH---------------------------------------QQHQQQQQLHQHQQQLSPNLSALHHHHQQQQQLRESGGSHSPSSPGGGGG--GSPYNG-------------SQAGCSS--------GGISPIPPQMG----------VSPKYRRSISFPIKGNSPTAIYGNMHMDGMGSGHMNIPTLSIGNGGGGGSTGMVSAG-ATGGGDAPYLGNSYG--NMMTSNGQMHHGGGLDNSLCDYMRN----MSLG-------------------------------GNGGGDGSNSMSLMQDRMRVMGGPKHLSEADAMAIAASGNDPSVYLN--------------------------ALKMGSPSRLSPHSPH------SPIQGGNGGNVGDGTARFSRKVFVGGLPPDIDEDEITTSFRRFGPLVVDWPHKAESKSYFPPKGYAFLLFQDESSVQQLIDSCITDEDKLYLCVSSPTIKDKAVQIRPWRLADADYVLDATMSLDPRKTVFVGGVPRPLKAFELAMIMDRLYGGVCYAGIDTDPELKYPKGAGRVAFSNQQSYIAAISARFVQLQHGDIDKRVEVKPYVLDDQMCDECEGQRCGGKFAPFFCANVTCLQYYCEHCWAVIHSRPGREYHKPLVKEGADRPRAVPFRWC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* .. . **:.**: :. : . *: :** :.. : .* .:. *. : *. *: .: . . *: .* . :: * .: . :::.: .* :.* . *. * ** .. : :* .:: . . :. . .* * : ** : :.. . *. : .. : *: *********************:****** **************************:*:*** **::*: ::.**************.******.*:*:*:*:*.: .******:*********:*.***********************************************************************:****:* **********************.*** ****.***:************* : *** ", "identical_positions": 253, "similar_positions": 99, "identity": "24.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-640", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60906-1", "uniprot_id": "NSMA_HUMAN", "id": "O60906-1", "name": "Sphingomyelin phosphodiesterase 2", "aln": "MKPNFSLRLRIFNLNCWGIPYLSKHRADRMRRLGDFLNQESFDLALLEEVWSEQDFQYLRQKLSPTYPAAHHFRSGIIGSGLCVFSKHPIQELTQHIYTLNGYPYMIHHGDWFSGKAVGLLVLHLSGMVLNAYVTHLHAEYNRQKDIYLAHRVAQAWELAQFIHHTSKKADVVLLCGDLNMHPEDLGCCLLKEWTGLHDAYLETRDFKGSEEGNTMVPKNCYVSQQELKPFPFGVRIDYVLYKAVSGFYISCKSFETTTGFDPHRGTPLSDHEALMATLFVRHSPPQQ---NPSSTHGPAERSPLMCVLKEAWTELGLGMAQARWWATFASYVIGLGLLLLALLCVLAAG---------GGAGEAAILLWTPSVGLVLWAGAFYLFHVQEVNGLYRAQAELQHVLGRAREAQDLGPEPQPALLLGQQEGDRTKEQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70572-1", "uniprot_id": "NSMA_MOUSE", "id": "O70572-1", "name": "Sphingomyelin phosphodiesterase 2", "aln": "MKLNFSLRLRVFNLNCWDIPYLSKHRADRMKRLGDFLNLENFDLALLEEVWSEQDFQYLRQRLSLTYPDAHYFRSGMIGSGLCVFSKHPIQEIFQHVYSLNGYPYMFHHGDWFCGKSVGLLVLRLSGLVLNAYVTHLHAEYSRQKDIYFAHRVAQAWELAQFIHHTSKNADVVLLCGDLNMHPKDLGCCLLKEWTGLHDAFVETEDFKGSDDGCTMVPKNCYVSQQDLGPFPSGIRIDYVLYKAVSEFHVCCETLKTTTGCDPHSDKPFSDHEALMATLYVKHSPPQE---DPCTACGPLERSDLISVLREARTELGLGIAKARWWAAFSGYVIVWGLSLLVLLCVLAAG---------EEAREVAIILCIPSVGLVLVAGAVYLFHKQEAKGLCRAQAEMLHVLTRETETQDRGSEPHLAYCL-QQEGDRA----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FBR1-1", "uniprot_id": "E7FBR1_DANRE", "id": "E7FBR1-1", "name": "sphingomyelin phosphodiesterase", "aln": "MTTSEPIKFRVLSLNCWGIQYLSKKRQERFVLIGELLNQEELDVALLQEVWCEKDFLYLKKKLSTVYPHSHYFKSGFFGSGLAVFSRHQIHDAFLYRYSLNGYPYMAQHGDWFGGKAVGKVLLNISGLKVHVFVTHLHAEYCREKDSYLSHRVVQAWELQQFIRHTSAGADVVILGGDLNMHPDDLGTRLLRNYTGLQDSFTEAATFDGCEGGLTHISENPFTLADGLAPFGGGIRIDYIMFKGSGEVDVSCESLSTTKGPVPGQPFPYSDHEALTAQFLFTPTKKGNKCAENKSGCVLDDLPELVNTVNEARTEVKVGLHCSEGMRYTAARTGIMGLVLLILELVIAAIPLFALGAEQPFPKATFYLLGALCFAILLSTLMLYIFYSMEVKALQGTEDQMRLAVSSLQEQLKEYPKVLFSDRQQNPLDCKNLAHL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . .:::*::.****.* ****:* :*: :*::** *.:*:***:***.*:** **:::** .** :*:*:**::****.***:* *:: : *:******* :***** **:** ::*.:**: ::.:******** *:** *::***.***** ***:*** ****:* *******.*** **:::***:*:: *: *.*.: * * :.:* :. : * ** *:****:::*. . . :.*:::.**.* * * ****** * : . : : : : : . *: .:.** **: :*: :. :. . ** ** * *:** . . :* ...::* : .*:*: *.:.* :: :: .: * . .: : : . : ", "identical_positions": 162, "similar_positions": 134, "identity": "37.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-642", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P16860-1", "uniprot_id": "ANFB_HUMAN", "id": "P16860-1", "name": "Natriuretic peptides B", "aln": "MDPQTAPSRALLLLL-FLHLAFLGGRSHPLGSPGS-ASDLETSGLQEQRNHLQGKLSELQVEQTSLEPLQESPRPTGVWKSREVATEGIRGHRKMVLYTLRAPRSPKMVQGSGCFGRKMDRISSSSGLGCKVLRRH-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P40753-1", "uniprot_id": "ANFB_MOUSE", "id": "P40753-1", "name": "Natriuretic peptides B", "aln": "MDLLKVLSQMILFLL-FLYLSPLGGHSYPLGSP---SQSPEQFKMQKLLELIREKSEEMAQRQLLKDQGLTKEHPKRVLRSQ-----------GSTLRVQQRPQNSKVTHISSCFGHKIDRIGSVSRLGCNALKLL-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1R8L8-1", "uniprot_id": "F1R8L8_DANRE", "id": "F1R8L8-1", "name": "", "aln": "MKSLHIPVVGLLFLLSVQHMRTFPLQSTALTNDDMGVLKFLLQRLEESIPAQDQTPAEREVKAANIEETRAEEQPDTYLREY------------LSARDLKTVRKDSKKKNSGCFGSKLDRIGSMSSLGCNTVGRSGPKKN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :*:** . :: : :* .* . . ::: . * . : . :* :. : :. . : *.*** *:***.* * ***:.: ", "identical_positions": 21, "similar_positions": 32, "identity": "14.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-643", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UKV5-1", "uniprot_id": "AMFR_HUMAN", "id": "Q9UKV5-1", "name": "E3 ubiquitin-protein ligase AMFR", "aln": "MPLLFLERFPWPSLRTYTGLSGLALLGTIISAYRALSQPEAGPGEPDQLTASLQPEPPAPARPSAGGPRARDVAQYLLSDSLFVWVLVNTACCVLMLVAKLIQCIVFGPLRVSERQHLKDKFWNFIFYKFIFIFGVLNVQTVEEVVMWCLWFAGLVFLHLMVQLCKDRFEYLSFSP-TTPMSSHGRVLSLLVAMLLSCCGLAAVCSITGYTHGMHTLAFMAAESLLVTVRTAHVILRYVIHLWDLNHEGTWEGKGTYVYYTDFVMELTLLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYLRVVGNMEARFAVATPEELAVNNDDCAICWDSMQAARKLPCGHLFHNSCLRSWLEQDTSCPTCRMSLNIADNNRVREEHQGENLDENLVPVAAAEG--RPRLNQHNHFFHFDGSRIASWLPSFSVEVMHTTNILGITQASNSQLNAMAHQIQEMFPQVPYHLVLQDLQLTRSVEITTDNILEGRIQVPFPTQRSDSIRPALNSPVERPSSDQEEGETSAQTERVPLDLSPRLEETLDFGEVEVEPSEVEDFEARGSRFSKSADERQRMLVQRKDELLQQARKRFLNKSSEDDAASESFLPSEGASSDPVTLRRRMLAAAAERRLQKQQTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9R049-1", "uniprot_id": "AMFR_MOUSE", "id": "Q9R049-1", "name": "E3 ubiquitin-protein ligase AMFR", "aln": "MPLLFLERFPWPSLRTYTGLSGLALLGTIVSAYRALSQPEDGSGEPEPLTAPLQPEALAPARLTAGGPRARDVAQYLLSDSLFVWVLVNTACCVLMLVAKLIQCIVFGPLRVSERQHLKDKFWNFIFYKFIFIFGVLNVQTVEEVVMWCLWFAGLVFLHLMVQLCKDRFEYLSFSP-TTPMSSHGRVLSLLIAMLLSCCGLAVVCCVTGYTHGMHTLAFMAAESLLVTVRTAHVILRYVIHLWDLNHEGTWEGKGTYVYYTDFVMELALLSLDLMHHIHMLLFGNIWLSMASLVIFMQLRYLFHEVQRRIRRHKNYLRVVGNMEARFAVATPEELAVNNDDCAICWDSMQAARKLPCGHLFHNSCLRSWLEQDTSCPTCRMSLNIADGSRAREDHQGENLDENLVPVAAAEG--RPRLNQHNHFFHFDGSRIASWLPSFSVEVMHTTNILGITQASNSQLNAMAHQIQEMFPQVPYHLVLQDLQMTRSVEITTDNILEGRIQVPFPTQRSDSLRPALNSPVERPSPDLEEGEASVQTERVPLDLSPRLEETLDFSEVELEPIEVEDFEARGSRFSKSADERQRMLVQRKDDLLQQARKRFLNKSSEDDGASERLLPSEGTSSDPVTLRRRMLAAAAERRLQRQRTT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1D5NS78-1", "uniprot_id": "A0A1D5NS78_DANRE", "id": "A0A1D5NS78-1", "name": "", "aln": "-----MDVLSWPCTQAYTAFSACLLTGCIYSLY----DDEDKDLLIEKNLSQDSPSGRTDDDNVNNEELYSTGLWCHTTGSLCMWVLVNTLCCFLLLMGKCIQLVVFGDLRINEKQNLKDKTWNFLFNKLIFLFGVLNVRTEREMAMWCLCFSALLFLQLLAQLCKDRFEFLSSSPSSTALGSHMHLLLVLMCLFVSSGGLTIICVLLGFSFGMHTLSFMAVECLMVSVYVNHSILRYAIHLYDLMCDSSWEGKEVFIYYTDFVMEMGILLLDMMHHINMLLYGNVWFSVADLFILTHIRFLAKEMQRKLFQHKNYMHIYDVMDTRFSMATMEELASRDDRCVICWEKMYTAYKLPCGHLFHKSCLRSWLEQNMSCPTCRMSVNMSGG------HTGNEQEGALFSLGATDVPSRPPTRYHSQLFHFNGSQISNWLPGFSVEVLHSPNLIILLQADDS----RGHQDEEIVP---------GLDLTE---------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :.**. ::**.:*. * * * * * : * : : .*. : . :.** :****** **.*:*:.* ** :*** **:.*:*:**** ***:* *:**:******:* .*:.**** *:.*:**:*:.********:** ** :*.:.** ::* :*:.:::*. **: :* : *::.*****:***.*.*:*:* . * ****.***:** :.:**** .::********: :* **:****:***:**:*:*:*.*.*: ::*:* :*:**:: :****::: . *::**::** **** .:* *.***:.* :* *********:*********: ********:*::.. * *:: : *..:.*:: ** . *.::***:**:*:.***.*****:*:.*:: : **.:* .** :*:.* .*::*. ", "identical_positions": 219, "similar_positions": 150, "identity": "33.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-645", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9P232-1", "uniprot_id": "CNTN3_HUMAN", "id": "Q9P232-1", "name": "Contactin-3", "aln": "MMFPWKQLILLSFIGCLGG------ELLLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGSDIDMSMEHRYKLNGGNLVVINPNRNWDTGTYQCFATNSLGTIVSREAKLQFAYLENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAALVLEERTQIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSWKKGDVSVQEHERISLLNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRSELVITWDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNGGGKEESSSKMKVAGNETSARLRGLKSNLAYYTAVRAYNSAGAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQNNVQVLNTNKTSAELVLPIKEDYIIEVKATTDGGDGTSSEQIRIPRITSMDARGSTSAISNVHPMSSYMPIVLFLIVYVLW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q07409-1", "uniprot_id": "CNTN3_MOUSE", "id": "Q07409-1", "name": "Contactin-3", "aln": "MMLSWKQLILLSFIGCLAG------ELLLQGPVFIKEPSNSIFPVDSEDKKITLNCEARGNPSPHYRWQLNGSDIDTSLDHRYKLNGGNLIVINPNRNWDTGSYQCFATNSLGTIVSREAKLQFAYLENFKTRMRSTVSVREGQGVVLLCGPPPHSGELSYAWVFNEYPSFVEEDSRRFVSQETGHLYIAKVEPSDVGNYTCVVTSTVTNTRVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVRLECFALGNPVPQINWRRSDGMPFPNKIKLRKFNGMLEIQNFQQEDTGSYECIAENSRGKNVARGRLTYYAKPYWLQLLRDVEIAVEDSLYWECRASGKPKPSYRWLKNGDALVLEERIQIENGALTITNLNVTDSGMFQCIAENKHGLIYSSAELKVVASAPDFSRNPMKKMVQVQVGSLVILDCKPRASPRALSFWKKGDMMVREQARVSFLNDGGLKIMNVTKADAGTYTCTAENQFGKANGTTHLVVTEPTRIILAPSNMDVAVGESVILPCQVQHDPLLDIMFAWYFNGALTDFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAAELIVRGSPGPPENVKVDEITDTTAQLSWTEGTDSHSPVISYAVQARTPFSVGWQSVRTVPEVIDGKTHTATVVELNPWVEYEFRIVASNKIGGGEPSLPSEKVRTEEAAPEIAPSEVSGGGGSRSELVITWDPVPEELQNGGGFGYVVAFRPLGVTTWIQTVVTSPDNPRYVFRNESIVPFSPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSHISAHSLSSSEIEVSWNTIPWKLSNGHLLGYEVRYWNNGGEEESSRKVKVAGNQTSAVLRGLKSNLAYYTAVRAYNSAGAGPFSATVNATTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTSSQNNVHVLNTNKTSAELLLPIKEDYIIEVKATTDGGDGTSSEQIRIPRITSMDARGSTSAISNIHPLSGYMSVLLFFIVNALW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7EZG5-1", "uniprot_id": "E7EZG5_DANRE", "id": "E7EZG5-1", "name": "", "aln": "MTLLWKRLVALSIIGCLAVSLAQAEDAKFSGPSWKREPEDLILPIYSPQQEAVLSCEASGAPSPQYRWSLNGTLIDLGGDERRRLSGGNLIITGLDRDQDSGVYQCTAFNTRGTILSQRATLQFAYLENFKTQTRSAVNVREGQGVVLLCGTPLHSGELTFTWVFNEYPHFVQQDSRRFVSQETGNLYIAKVEPSDVGNYTCVVNNTITKERVFSSPTPLVLRNDGAMGEYEPKIELHFPDTIPAAKGSALKLECFALGNPVPRISWRRTSDVSFPNKVKLKNSNAILEIPSFQQEDTGTYECIAENSRGKNAARGRVSFHATPHWLQTMTDTAMSIEENLFWECKANGKPKPSYSWLKNGESLISEGRVQIENGALSIFSLNLSDGGMYQCVAENKHGIIYSSAELMVLASAPSFSQNPLSQTLKARSGSDVSLDCRPHASPRAISLWKRGTEILQRNERTFLFPNGTLKITNITKRDGGSYTCVAKNQFGTASTTGKLIITEPTRISQSPSSTEITVGESVVLPCQVTADPALDVAFSWAFNGQPIDFHQDADHFERVGGSFSGDLMIRNIQLNHGGKYVCLVDTDVESLSADAILVVKGPPSPPDMVVVEEVTDSTAQLSWSPGQDNGSPITGYAIQGRTPFTVGWQAVDTVPEVINGNTLTATVVGLNAWVEYEFRVLASNSVGMGEPSPPSTKIRTEDSMPDAAPTDVGGGGGTKSELVITWEPVPEELQNGEGFGYIIAFRPVGMVTWTRVVISAPSLTRYVFRNDTIPPFSPFNVKVGAFNNRGEGPFSTIATVFSAEEVPSIAPEKVSAKSLSAADIEVTWEPIASIPER--VLGYEVVYWEDDTKPDTVGKVRITGNYTAVNVSGLQGNTQYYLAVCAFNTAGTGPQSAPVNITTKKPPPGQPPQNVEWNLIGSQLILQWDPVIALETESEVTGYIVLYRRHRNNDMYSIITNKTSAELTLNPNDNYVIQIKSLSEGGLGEGSEPIHIHQLS-MGARGSRSGRLCSLSLSPLLICALSSLGAS--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : **:*: **:****. : :.** : :**.: *:*: * ::: .* *** * ***:***.***: ** . :.* :*.****:: . :*: *:* *** * *: ***:*:.*.***********: **:*.************.* *****:::*:***** **::***********:***:**************.. :*: **:.********.**.*********::**:*:******:::*********:*:*.***:..:.*..*:**:: ..:*** .*****:*:************.****::::*.*:*:* : *. :::*:.*:***:*.******* ***** :*: * * *******:* .*.::*.**:**:******::****** *:****.**:**:.: ::.: ** * ***:*:*****:* **:* ::.: * :: :* *** *:** *.*:*** *:****.*. * :*::****** :**. :::*****:***** ** **: *:* *** **::*..***:**** ***********:*.*****:*:*.*:*:*: * *:*:*.*.**: * *:*:**:******. * *. **: .*::*.****:****:* ******:*:* ***** **.*******::***.:* **** ** *:***:: *: .*::*.****::*******:********* ****::****:*:.** :.*:::*. .******::* *:**::****.:**:******.::******* *::**.::**:***:::***:*:.*. .. :***** **:.. : :: *::::** *:. : **:.* ** ** *:*:**:** **.** ****.**.*** ** ** .::::*:*: * *:*.******* *:** :*:: : ******** * :::*:*::*: ::** * .** *:* ::: *.**** *. .:* : * : ", "identical_positions": 582, "similar_positions": 293, "identity": "56.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-649", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q811F1-1", "uniprot_id": "ZBT41_MOUSE", "id": "Q811F1-1", "name": "Zinc finger and BTB domain-containing protein 41", "aln": "MKKRRKVTSNLDEKIHLGYHKDSSEENAAVECGQVTYTQAPERPTPEAAQRCQELPPSPDQRKLLSSLQYNKNLLKYLNDDRQKQPSFCDLLIIVEGKEFSAHKVVVAVGSSYFHACLSKNPSTDVVTLDHVTHSVFQHLLEFLYTSEFFVYKYEIPLVLEAAKFLDIIDAVKLLNNENVAAFQAELTEKSSPEETLNELTGRLSSSHQCKFCSRHFCYKKSLENHLAKTHRSLLLGKKHGLKMLERSFSTRRSKRNRKCPVKFEDTSDD----------EQESGDGSDNLHQESSEKERSDRNDSEDPGSEYNAEDEE----LEEEVSDEDSDTE-QSDKD-NDAEEEPE-------------AGDSAGSIHEGLAPVIIQNSNKKILQCPKCDKTFDRIGKYESHTRVHTGEKPFECDICHQRYSTKSNLTVHRKKHSNEVEFHRKEHKCPYCNKLHASKKTLAKHVKRFHPENAQEFISIKKTKSESWKCDICKKSFTRRPHLEEHMILHSQDKPFKCTYCEEHFKSRFARLKHQEKFHLGPFPCDICGRQFNDTGNLKRHIECTHGGKRKWTCFICGKSVRERTTLKEHLRIHSGEKPHLCSICGQSFRHGSSYRLHLRVHHDDKRYECDECGKTFIRHDHLTKHKKIHSGEKAHQCEECGKCFGRRDHLTVHYKSVHLGEKVWQKYKATFHQCDVCKKIFKGKSSLEMHFRTHSGEKPYKCQICNQSFRIKKTLTKHLVIHSDARPFNCQHCNATFKRKDKLKYHIDHVHGIKSPDDSLSTSEEKLMSLPMEYSSDDKIFQAETKQYLDQPKVYQSEAKTMLQNVSAEVCVPVTLVPVQMPDTSSDLVPHTTTLPTSSHEMLPPQPQSTDYPRAADLAFLEKYTLTPQPANIVHPVRPEQMLDPREPSYLGTLLGLDSTAAVQNMCSSEHRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SVQ8-1", "uniprot_id": "ZBT41_HUMAN", "id": "Q5SVQ8-1", "name": "Zinc finger and BTB domain-containing protein 41", "aln": "MKKRRKVTSNL-EKIHLGYHKDSSEGNVAVECDQVTYTHSAGRPTPEALHCYQELPPSPDQRKLLSSLQYNKNLLKYLNDDRQKQPSFCDLLIIVEGKEFSAHKVVVAVGSSYFHACLSKNPSTDVVTLDHVTHSVFQHLLEFLYTSEFFVYKYEIPLVLEAAKFLDIIDAVKLLNNENVAPFHSELTEKSSPEETLNELTGRLSNNHQCKFCSRHFCYKKSLENHLAKTHRSLLLGKKHGLKMLERSFSARRSKRNRKCPVKFDDTSDD----------EQESGDGSDNLNQENFDKEKSDRNDSEDPGSEYNAEEDE----LEEEMSDEYSDIEEQSEKDHNDAEEEPE-------------AGDSVGNVHEGLTPVVIQNSNKKILQCPKCDKTFDRIGKYESHTRVHTGEKPFECDICHQRYSTKSNLTVHRKKHSNETEFHKKEHKCPYCNKLHASKKTLAKHVKRFHPENAQEFISIKKTKSESWKCDICKKSFTRRPHLEEHMILHSQDKPFKCTYCEEHFKSRFARLKHQEKFHLGPFPCDICGRQFNDTGNLKRHIECTHGGKRKWTCFICGKSVRERTTLKEHLRIHSGEKPHLCSICGQSFRHGSSYRLHLRVHHDDKRYECDECGKTFIRHDHLTKHKKIHSGEKAHQCEECGKCFGRRDHLTVHYKSVHLGEKVWQKYKATFHQCDVCKKIFKGKSSLEMHFRTHSGEKPYKCQICNQSFRIKKTLTKHLVIHSDARPFNCQHCNATFKRKDKLKYHIDHVHEIKSPDDPLSTSEEKLVSLPVEYSSDDKIFQTETKQYMDQPKVYQSEAKTMLQNVSAEVCVPVTLVPVQMPDTPSDLVRHTTTLPPSSHEILSPQPQSTDYPRAADLAFLEKYTLTPQPANIVHPVRPEQMLDPREQSYLGTLLGLDSTTGVQNISTNEHHS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6PFI6-1", "uniprot_id": "F6PFI6_DANRE", "id": "F6PFI6-1", "name": "Zinc finger and BTB domain-containing protein 41", "aln": "MKKKLNP-------------KETQETTTACNS------------KRDVGMTIKDFS---LEKKCLRISQNDGCFLKFLNEDRHKLSSFCDTTVTVSGRIYHAHKVVLAFGSGYFHSRFSENPELHHVSIDNMEGSTFGHLLNFLYTSEFEVSECQIPALAEAACFLDMMEAVNILAKWAAPANADEESE--VPEEIPNFQNIQTSSGTKCLFCSRTFNYKKSLENHLAKTHSTGCHNEEEQTVVSTSVVTIRRSARQRRVPAKFKSQDSENECVVSAKPNQKIANHNSVTYEEEEEDNESKEENENEQIQQESWKEGQEETFVALEVEAAEYEDCEKPKEACVSEAQKETEPAFSHALEEHNQKTEVSSHIFPEGLAPVVIHSTNKKSLKCPKCDKIFDRKGKYESHTRVHTGEKPFQCDICLQCYSTKSNLTVHKKKHDSGTPVQRKEHKCPFCNKLHASKKTLSRHVKRFHPDHLQEFLTQKK-KSEVWKCDICHKSFSRRPHLEEHMILHSQDKPFKCAYCDDYFKSRFARLKHQEKFHLGPFPCDICGRQFNDTGNRKRHIECTHGGKRKWTCFLCGKSVRERTTLREHLRIHSGEKPHLCSICGQSFRHGSSYRLHLRVHHEDKRYECEECGKTFIRHDHLKKHKKIHTGEKAHQCEECGKCFRRADHLTVHYKSIHLGEKIWQRYKAVVHQCQVCKKEFRGKTNLMSHFRTHSGEKPHKCVICNQTFSIKKTLTKHMVIHSDVRPFNCPHCSATFKRKDKLKYHVDHVHSVRLLDQQQNQP----------ASPANKLIDPSLSNKNSKP--CQNASKTVLQSVAADVCVPVTLIPVQMTEEA-DLAVHG--VPHGILPALS-QPQ-QSYQSATDLVFLEKYTLTPQPTNIVHPVRVEQMLDPREQSYLGTLLGLDSATPVQNTSSAEHTQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***: : *::.* ..* :. . :. :::. ::* * * : :**:**:**:* .**** : *.*: : *****:*.**.***: :*:**. . *::*:: *.* ***:******* * : :** : *** ***:::**::* : ... * :* *** * . : *.. :* **** * ************* : .::. : .: *** *:*: *.**.. ..: :: :...* . .:*. ::* .:.*:.*: .* * :* * : * .* * .: .:*::*.* : * . ***:**:*:.:*** *:****** *** ****************:**** * **********:***.. . .::******:***********::*******:: ***:: ** *** ******:***:********************:**:::********************************* *****************:***********:***********************************:******:************.******:************** * *********:*****:**:***..***:**** *:**:.* **********:** ****:* ********:*****.***** **.************:**** :: *: . . *. :*:::.. .: .:* *. :**:**.*:*:*******:****.: . **. * :* . *. *** .* *:**.***********:******* ******** ***********:: *** .: ** .", "identical_positions": 522, "similar_positions": 194, "identity": "55.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-650", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61702-1", "uniprot_id": "ITIH1_MOUSE", "id": "Q61702-1", "name": "Inter-alpha-trypsin inhibitor heavy chain H1", "aln": "MEGATG---LRVLLCLLPLLTLQARPALGLATGRPRGSEKRHAVDTSVNGVSIKSLKVNCKVTSRFAHYVITSQVVNNADKAREVAFDVEIPKTAFISDFAITSDGKAFIGDIKDKVTAWKQYRKAAVLGESAGLVRASGRNMEQFTIHITVGAQSKATFRLTYEEVLKRRLMQYDITIKVRPKQLVQHFEIDVDIFEPQGISKLDAQASFLSEELAAQTIKKSFSGKKGHVLFRPTVSQQQSCPTCSTSLLNGEFKVTYDVNRDK-LCDLLVANNYFTHFFAPKNLTNMSKNLVFVIDISGSMEGQKVRQTKEALLKILEDMRPVDNFDLVLFGSKVQSWKGSLVPASNANLQAAQDFVRRFSLAGATNLNGGLLRGIEILN-KAQGSHPELSSPASILIMLTDGEPTEGETDRSQILKNVRNAIRGRFPLYNLGFGHDLDFSFLEVMSTENNGWAQRIYEDHDATQQLQGFYNQVANPLLTDVELQYPQDAVLALTQHRHKQYYDGSEIVVAGRIANHKLNTFKADVRARGEKQEFRATCLVDEEEMKKLLRERGHVLENHVERLWAYLTIQELLAKRMKTEGEERANLSSQVLKMSLDYHFVTPLTSLTIRGLTDEDGLEPTIDKPLE----DSQPLEMVGP----RRTFVLSAIQPSPTAHPIDSK-LPLRVTGVDTDPHFIIYVPSKEDSLCFNINEEPGVILNLVQDPDTGFTVNGQLIGNKASSPGQHESTYFGRLGISSPTSDFQLEVTPQNITLNPSSSGSMFSWRDQAVLQKDGVVVTINKKRNLVVSVDDGATFEIVLHRTWKGSAVHQDFLGFYVLDSFRMSARTKGLLGQFFSPLDFEVFDLHPGSDPTKTDATMVVKNRQLTVTRGLQKDYSKDPRHGAEVPCWFVHDNGAGLIDGVHTDYVVSDIF---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19827-1", "uniprot_id": "ITIH1_HUMAN", "id": "P19827-1", "name": "Inter-alpha-trypsin inhibitor heavy chain H1", "aln": "MDGAMGPRGLLLCMYLVSLLILQAMPALGSATGRSKSSEKRQAVDTAVDGVFIRSLKVNCKVTSRFAHYVVTSQVVNTANEAREVAFDLEIPKTAFISDFAVTADGNAFIGDIKDKVTAWKQYRKAAISGENAGLVRASGRTMEQFTIHLTVNPQSKVTFQLTYEEVLKRNHMQYEIVIKVKPKQLVHHFEIDVDIFEPQGISKLDAQASFLPKELAAQTIKKSFSGKKGHVLFRPTVSQQQSCPTCSTSLLNGHFKVTYDVSRDK-ICDLLVANNHFAHFFAPQNLTNMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILN-QVQESLPELSNHASILIMLTDGDPTEGVTDRSQILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMSMENNGRAQRIYEDHDATQQLQGFYSQVAKPLLVDVDLQYPQDAVLALTQNHHKQYYEGSEIVVAGRIADNKQSSFKADVQAHGEGQEFSITCLVDEEEMKKLLRERGHMLENHVERLWAYLTIQELLAKRMKVDREERANLSSQALQMSLDYGFVTPLTSMSIRGMADQDGLKPTIDKPSE----DSPPLEMLGP----RRTFVLSALQPSPTHSSSNTQRLPDRVTGVDTDPHFIIHVPQKEDTLCFNINEEPGVILSLVQDPNTGFSVNGQLIGNKARSPGQHDGTYFGRLGIANPATDFQLEVTPQNITLNPGFGGPVFSWRDQAVLRQDGVVVTINKKRNLVVSVDDGGTFEVVLHRVWKGSSVHQDFLGFYVLDSHRMSARTHGLLGQFFHPIGFEVSDIHPGSDPTKPDATMVVRNRRLTVTRGLQKDYSKDPWHGAEVSCWFIHNNGAGLIDGAYTDYIVPDIF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5R8-1", "uniprot_id": "A0ACD6B5R8_DANRE", "id": "A0ACD6B5R8-1", "name": "Inter-alpha-trypsin inhibitor heavy chain H3", "aln": "---------MSAVKVMLWMFVLFCLIFIAKAQVTIKDDS-----NNSAKQIELQSMRVDCKVASRFAHTVMTTRALNTAKASQEVFFEVDLPKTAFITNFSIEIENRIYVSEVKEKEQARQKYESAVISGQTAGLVKASGRHMEKFSVSVNIAAQSSVTFTLTYEELLQRRLGSYEIMIGVRPKQLVQNFEIVVDIYEPKGIAFVDVNGTFITNELLP-LVKKTVTDKKAHVYFSPTLDQQKKCLNCEATLIDGDLFIKYDVNHAQDIGEIQIVNGYFVHFFAPEGLPQMPKNVVFVIDRSGSMMGEKMKQTQEALTTILSELHEDDYFGLVTFDDVIESWRPSLSKATPENVTEAKEYVQTINARSMTDINKGILYAVDMLTSEKSASFPNMS----MIILLTDGQPSSGEQDLSKIQENVRNAINGSMSLFCLGFGYDLDYILLDTLAKQNDGLARRVYEASDAALQLQGFYEEVATPLLIEVNLNYPDNAVTDVTQSHFRHFFKGSEIVVAGRLQELEINTFPTEVSANGLEDQFVMQGVAIAEEWDSVFPEQEYIFGDFIERLWAYLTIQQLLDKREKCSPEDKENTTAEALSLSLRYNFVTPLTSMVVTKPQTDDEETLVADKLTEEQREDIPQAGMRAPSQLTGTSQRLRQYSQVPLFGGTASQRRLTPSSLVDGDPHFIIELPDQNNALCFNIDDKPGTIFNLVRDPLTGIMVNGQIIGDKKIIPGSKLHTYFGRFGIVDEKLGIRLMVSTQEIWVSEGGKQTKLSWTNKRTIKGLNMDLQVIKDQSLTVTLKNSVKFLIILHKIWRKHPYHQDYLGFYTLDSHQLSQDVHGLLGQFYHGINFEVSDLFPGKDADKQDAVMFVKRNKLTVTRGWKRDFRQDVKNGDDVPCWFIHNNGTGLIDGVHTDYIVSGLFKTI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :: * . :. * :... :.:.. : ::*::*:***:***** *:*::.:*.*. ::** *::::******::*:: :.. ::.::*:* * ::*..*.: *:.****:**** **:*:: :.: .**..** *****:*:*. .*:* * *:*****::*** ***:**:**: :*.:.:*:.:** . :**:.:.**.** * **:.**:.* .*.::*::*.: :.***.: : : :: :.*.:*.*****:.*.:* **:***** **** *:*::**:*** .** ::: * *.** *. ::**: ** *: *: *:::*: :. *::* *:* .:::*. : . * *::* ::*:****:*:.* * *:* :******.* :.*: ****:::*: :*:.:: :*:* *:*:** **: ******.:**.*** :*:*:**::** :** :.::::.*********: : : .:* ::* *.* ::* :. ** ..:: *: ::: :.:**********:** ** * . *:: * :::.*.:** * *******: : :* . ** * * * .* : * . * :: : ** ****** :*.::::*****:::**.*:.**:** **: ****:**:* **.: *****:** . .::* *:.*:* :. . . :** :: .:: .: : : *.:.*.*::.:. .* ::**: *: . ***:****.***.::* .:******: :.*** *:.**.*. * **.*.*:..:****** ::*: :* :* :*.***:*:**:*****.:***:*..:* ", "identical_positions": 357, "similar_positions": 333, "identity": "38.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-653", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LTZ3-1", "uniprot_id": "F1LTZ3_RAT", "id": "F1LTZ3-1", "name": "", "aln": "----------------------MLWIVLLL--------------LLCTDSLV-----------QDLEFQLVAPK-SVTVEEALCVHVPCSVSYP-SIR--PTFGPVTGYWLLKGTSLHEDSPVATNDPRQLVQKATQGR-----FQLLGDPQKHDCSLLIRDAQKNDTGVYFFRVVREPFVRYSYRANQLLLHVTPLSRTPDIIIPETLRAGHPSNLSCSVPWACEQGTPPTFSWMSDALTSLSSR----TTNSSVLTLTPRPQDHGTKLTCLVTFSGAG--VTVERTIRLNVT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WKSDQMRQVVLVAVG-EAAVKLLILGLCLTLLSVVICRRKATKLSVHMNCENPYQGSPAGLQG-AQPC-------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6NMB1-1", "uniprot_id": "SIG16_HUMAN", "id": "A6NMB1-1", "name": "Sialic acid-binding Ig-like lectin 16", "aln": "---------------------MLLLPLLLP--------------VLGAGSLN-----------KDPSYSLQVQR-QVPVPEGLCVIVSCNLSYPRDGW--DESTAAYGYWFKGRTSPKTGAPVATNNQSREVAMSTRDR-----FQLTGDPGKGSCSLVIRDAQREDEAWYFFRVERGSRVRHSFLSNAFFLKVTALTQKPDVYIPETLEPGQPVTVICVFNWAFKKCPAPSFSWTGAALSPRRTRP--STSHFSVLSFTPSPQDHDTDLTCHVDFSRKG--VSAQRTVRLRVASLELQGNV----------------IYLEVQKGQFLRLLCAADSQPPATLSWVLQDRVLSSSHPWGPRTLGLELPGVKAGDSGRYTCRAENRLGSQQRALDLSVQYPPENLRVMVSQANRTVLENLRNGTSLRVLEGQSLRLVCVTHSSPPARLSWTWGEQTVGPSQPSDPGVLQLPRVQMEHEGEFTCHARHPLGSQRVSLSFSVHCKSGPMTGVVLVAVG-EVAMKILLLCLCLILLRVRSCRRKAARAALGMEAADAVTD-------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZAH6-1", "uniprot_id": "D3ZAH6_RAT", "id": "D3ZAH6-1", "name": "", "aln": "----------------------MLLSRLLP--------------LLWVFKWASGVCFLLPGMFRDINQSLKLELNSVTVQEGLCVLVPCKFIVN-PRN--MLSDLVFGYWYHEEKNTQLDSLVATNNPYQLVR-GTQSR-----FHLSGDLRFNDCSLDIRDAQKSDSGSYFFSLKKEG-MTWNFCEEKISVHVTDLTHTPSISIPQTLELGHPTDVICSVPWACERGTPPIFSWMSAAPISLGPT----TTFSSVLTLTPRLQDHGTYLTCQVTFPGVG--VTVQKTVQINVTYTAQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STSHVSGRASPGKTEHLAEVVQVAMG-EAAIKFLLLGICFFFLSMRPHEKRVERPATHVDHSATVMD-------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0M7S7-1", "uniprot_id": "A0ABK0M7S7_RAT", "id": "A0ABK0M7S7-1", "name": "", "aln": "MRQFRSGGRLFLADFGSHDATQEKWKCLFSKGLDIADNLRVESSFLLCGSLA------------VENYELSLTE-SVTVQEGLCVFVPCQVKYP------ASGGSVFGYWFQDGANTNLNSPVATNDPHRPVQQETQGR-----FYLVGGIDTKNCSLDIRDARKSDTGKYFFRL--DGSVKYSFRNRMLSVHVTALTKTPNLQVTSTLVSGTSTRVICSVLWACEQGTPPIFSWMSSALTSLGRR----TILSSELNLTPRPQDNGTNLICQVTFPGAG--VTVERTQQLSVTYAPQKLTIRVSWGDGTETKVLQSGASLQIQEGESLRLVCVADSNPSAMLSWKRQTQKNFRLS----KGDELQLPRVELEDQGKYICQAKNSLGTQTASVSLSIRSLLQLLAPSCSWDSEGLHCSCSSRAWPAPSLGWRLGEGLLEGNSSNASFTVMSSSAGPWVNSSLSLSVEFSTDHRLSCEAWNDYGVQRATIVLVPGQGVSQADKSETSGGAVQGAIWGAGLMALLAVSFCLIFFIVKFLRKKSALEVAAMEGNHLAKNLVSTINS-ASMISSNIPLRYPIQDHLNESESQTQKEEPPLATAPDIPKDEPELHYASLSFQGPRPQQPKNTETIKSVYTEIKIHKR-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q920G3-1", "uniprot_id": "SIGL5_MOUSE", "id": "Q920G3-1", "name": "Sialic acid-binding Ig-like lectin 5", "aln": "----------------------MRWAWLLP--------------LLWAGCLA------------TDGYSLSVTG-SVTVQEGLCVFVACQVQYP------NSKGPVFGYWFREGANIFSGSPVATNDPQRSVLKEAQGR-----FYLMGKENSHNCSLDIRDAQKIDTGTYFFRL--DGSVKYSFQKSMLSVLVIALTEVPNIQVTSTLVSGNSTKLLCSVPWACEQGTPPIFSWMSSALTSLGHR----TTLSSELNLTPRPQDNGTNLTCQVNLPGTG--VTVERTQQLSVIYAPQKMTIRVSWGDDTGTKVLQSGASLQIQEGESLSLVCMADSNPPAVLSWERPTQKPFQLS----TPAELQLPRAELEDQGKYICQAQNSQGAQTASVSLSIRSLLQLLGPSCSFEGQGLHCSCSSRAWPAPSLRWRLGEGVLEGNSSNGSFTVKSSSAGQWANSSLILSMEFSSNHRLSCEAWSDNRVQRATILLVSGPKVSQAGKSETSRGTVLGAIWGAGLMALLAVCLCLIFFTVKVLRKKSALKVAATKGNHLAKNPASTINS-ASITSSNIALGYPIQGHLNEPGSQTQKEQPPLATVPDTQKDEPELHYASLSFQGPMPPKPQNTEAMKSVYTEIKIHKC-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1M8J5-1", "uniprot_id": "F1M8J5_RAT", "id": "F1M8J5-1", "name": "", "aln": "----------------------MLLLLLLLWG------------IKGVEGGA----------VALKGYTLNVER-KVVVQEGLCVLVPCNFSYPKFWQ--TDSSPVYGYWFRKKANTDIDAPVATNNPKRPAQERTQHR-----FFLPGDQQKNDCSLNIREIKKKDAGTYFFRLE-RGKTKYNYLWNMMTLDVTALTNTLRI-LPETLEAGHPSNLTCSVPWDCEKRAPPVFSWNGTSVSPLSTN----TTGSSVLTIIPQPQDHGTNLTCQVTLPGTD--VTTRMTIRLNVSYAPKNLTVTVYQGADSVSTILKNGSSLQISEGQSLRLICSADSYPPANLSWS--------------------------------------------------------------------------------------------------------WGNLTLCPPKLSKPGLLELFPMHLKHEGVYTCQAQHALGSQYISLNLS-PQRSATLSEMMMGTLMDSGVTALLFLSFCIILLAVRSCRRKPARTAVVAPHPNALKVSVSQSPL-VESHAD------------------DSSEPLPSTVEAAPSSTKEEIHYASLSFHEMKPRNSWGQQGSTTEYSEIRLHK------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M6YX94-1", "uniprot_id": "A0A8M6YX94_DANRE", "id": "A0A8M6YX94-1", "name": "", "aln": "----------------------MGLAEKIS---------------IFVFLLQG---------VYCRDYDIFLPE-KIEALSGSCVIIECRFEIVPEMDKYLTEENAVGFWFNGKKEVFHSKHHKADHFEGTMSEKLHEKNCTTVFYNVGSDHNNKFYFRIESTVNGIGLKYSYNKK---LSTINVVESPVNPRIVLYEDEQELQDQQEVLEGRSVSLRCSAETLCS-IPPATLTWSSAGKILLSESSKLQELVVSALNFTAAPRHHRVTFTCSISYQLQDNNKTARSSIPLHVQYSPKNTSVSVFP-------------SNSVLVGHSVTLTCSSEANPAVLIYSWSRETKGQLEMLQT--GETLTFNETALSHSGLYICTAQNKHGTQTKAVMLDIQYVPQISSSSSCTSTGVTECFCEVDGNPYPEVEWHLSG----------HLVSNSPNTFISEKRLSNTSLRSVISLQSLTHNSLLCVSKNAHGNASQLFYLVFITENEWFNIYSLMIGVLAGTLFVVILWASILLCKRNRTQRTDKTILIRTDVADSVNNGEESFYANKVMMSSAEAPTQNHRDHLQYSTINFINNRPESNLVRGISSLTTEYAAIQYCSQNVAVSEATSGEVPSVLPNEDPVYQVPNKAADRTKRK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: . .. ** : * . . *:* . . ::. : : * * . : *.. . * : . . : : . : * . : * . ... ::* . . * *.: . :.: . : * : . :.. : : * .. .: : .: : .: ", "identical_positions": 16, "similar_positions": 65, "identity": "2.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-654", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAN9-1", "uniprot_id": "D3ZAN9_RAT", "id": "D3ZAN9-1", "name": "", "aln": "MRCTDVKVLRDKPPQSGPRDGGGGTAGAPPPRRRAASRRAPNSRPGPAAAAMKIWSSEHVFGHPWDTVIKAAMRKYPNPMNPCVVGVDVLERSVDGY-GRLHSLRLLSTEWGLPGLVRAILGANRTLTYIKERSVVDPAARKMELCSTNITLTNLVSVNERLVYTPHPENPE-KTVLTQEAIITVKG--ISLGSYLESLMATTISSNAKKGWAAIEWII--------------------------EHSESAIS------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VE85-1", "uniprot_id": "PLD3A_MOUSE", "id": "Q8VE85-1", "name": "PRELI domain containing protein 3A", "aln": "---------------------------------------------------MKIWSSEHVFGHPWDTVIKAAMRKYPNPMNPCVVGVDVLERSVDGC-GRLHSLRLLSTEWGLPGLVRAILGANRTLTYIKERSVVDPAARKMELCSTNITLTNLVSVNERLVYTPHPENPE-KTVLTQEAIITVKG--ISLGSYLESLMATTISSNAKKGWAAIEWII--------------------------EHSESAIS------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96N28-1", "uniprot_id": "PLD3A_HUMAN", "id": "Q96N28-1", "name": "PRELI domain containing protein 3A", "aln": "---------------------------------------------------MKIWSSEHVFGHPWDTVIQAAMRKYPNPMNPSVLGVDVLQRRVDGR-GRLHSLRLLSTEWGLPSLVRAILGTSRTLTYIREHSVVDPVEKKMELCSTNITLTNLVSVNERLVYTPHPENPE-MTVLTQEAIITVKG--ISLGSYLESLMANTISSNAKKGWAAIEWII--------------------------EHSESAVS------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EZZ3-1", "uniprot_id": "E7EZZ3_DANRE", "id": "E7EZZ3-1", "name": "", "aln": "---------------------------------------------------MKIWSTEHIFSYPWETVIKAAMRKYPNPMNPSVVGVDVLDRNLDTH-GRLHSHRLLSTEWGLPGVVKAILGTSRTVTYVKEHSIVDPEEKKMELCSTNITLTNLISVDERLVYRPHPDNPE-VTVLTQEAIITVKG--VSLSSYLEGLMALTMSANARKGWDAIEWII--------------------------QNSEREKCPFV---------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3U9-1", "uniprot_id": "SLMO_DROME", "id": "Q9V3U9-1", "name": "Protein slowmo", "aln": "---------------------------------------------------MKIWTSEHIFNHPWETVTQAAWRKYPNPMTPSIIGTDVVERRVVD--GVLHTHRLVQSKWYFPKWTHALIGTAKTC-FASERSTVDPERKQMVLKTNNLTFCRNISVDEVLYYEPHPSDAS-KTLLKQEATVTVFG--VPLSHYMEDLLTSTISTNAGKGRQGLEWVIGLINTEVKGIARGTDELLHNTRRSIDEVTESARKSMDEISAQAAKAAKAMHIT-----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35200-1", "uniprot_id": "UPS2_YEAST", "id": "P35200-1", "name": "Protein UPS2, mitochondrial", "aln": "---------------------------------------------------MKLFQNSYDFNYPWDQVTAANWKKYPNEISTHVIAVDVLRRELKDQGKVLVTERLITVKQGVPKWIMMMLGG-TNMSHVREVSVVDLNKKSLTMRSCNLTMCNLLKVYETVTYSPHPDDSANKTLFQQEAQITAYGSIRKLCNKMEDWSVQRFCENAKKGKMGFDAVLQ-------------------------VFSENWEKHVDDLSNQLVSKVNETMEDVKISAGTLLKGTERSGRTILQQNIDLFRDAYNHEN", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q04006-1", "uniprot_id": "UPS3_YEAST", "id": "Q04006-1", "name": "Protein UPS3, mitochondrial", "aln": "---------------------------------------------------MKSFQKSYEFDYPWEKVTTANWMKYPNKISTHVIAVDVLRRELKEHGDVLLTERLITIRQNTPHWMSILVGN-TNLAYVREVSTVDRRDRSLTMRSCNMTFPHILKCYETVRYVPHPKNPSNVTLFKQDAKFLSGVPTKTFSEKVENWGVKRFSDNAVKGKVGFDSILA-------------------------MFNDIWKN------------ANE---------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : ..: *.:**: * * **** :.. ::..**: * : * : **: . * ::* . . * * ** :.: : : *:*: . :. * : * ***.:. *:: *:* . : :*. . :. ** ** .:: :: .: ", "identical_positions": 38, "similar_positions": 54, "identity": "12.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-662", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZM29-1", "uniprot_id": "A0A8I5ZM29_RAT", "id": "A0A8I5ZM29-1", "name": "", "aln": "MGKRAG---GGAAAAAASASSGARLEPAAGRGGGPRSAAAGLLGALHLVMTLVVAAARAEKEAFIQSESIIEVLRFDDGGLLQTETTLGLSSYQQKSISLYRGNCRPIRFEPPMLDFHEQPVGMPKMEKVYLHNPSSEETITLVSISATTSHFHASFFQNRKILPGGNTSFDVVFLARVVGNVENTLFINTSNHGVFTYQVFGVGVPNPYRLRPFLGARVPVNSSFSPVINIHNPHSEPLQVVEMYSSGGDLHLELPTGQQGGTRKLWEIPPYETKGVMRASFSSRDADNHTAFIRIKTNASDSTEFIILPVEVEVTTAPGIYSSTEMLDFGTLRTQDLPKVLNLHLLNSGTKDVPITSVRPTPQNDAITVHFKPVTLKASESKYTKVASISFDASRAKKPSQFSGKITVKAKEKSYSKLEIPYQAEVLDGYLGFDHAATLFHIQDSP---ADPVER--PIYLTNTFSFAILIHDVLLPEEARTMFQVHNFSKPVLILPNESGYIFTLFFMPSTSSMHIDNNILLVTNASKFHLPVRVYTGFLDYFVLPPKIEER-----------FIDFGVLSATEASSILFAIINS-NPIELAIKSWHIIGDGLSIELVATERGNRSTVIASLPELEKSSLPDQSPVTLASGHFAVFRVKLTAKKLEGVHDGAIQITTDYEILTIPVKAVVAVGSLTCFPKHMVLPPSFPGKIVHQSLNVMNSFSQKVKIQQIRSLSEDVRFYYRRLRGNREDLEPGKKSKIANIYFDPGLQCGDHCYIGLP-FLSKSEPKVQPGVAMQEDLWDADWEAHQSLFKAWMGIKENAGHRLNAM-FEVNTDLQKNIISKVSAELSWPSVLSS-PRLVRFPLTNTNCSSEEEISVENPADVPVYVQFIPLALYSNPSVFADKLVSRFNLSKVAKLDLRT--LEFQVYRNSAHPLQSPTGFTEGLSRHFILNLILKPGEKKSVTVKFTPLHNRTVSSLIIVRNNLTVMDAVMVQGQGTTENLRVAGKLPGPGSSLRFKITEALLKDCIDRLKLREPNFTLKRTFKVENAGHLEIRVETIEISGYACEGYGFKVVNCQEFALSANASRDIVILFTPDFTASRVIRELKFVTSSGSEFVFVLNASLPYHMLAACAEALPRPNWELALYIIISGVMSALFLLVIGTAYLEAQGIWEPFRRRLSFEASNPPFDVGRPFDLRRIVGISSEGNLNTLG-CEHSHGRGFYSN--SSSRPGTGSHRQCGTSVHPHSSHGSKNSADVDNVRTRNSSSMSSRTSPQAATSQSTSKTSPLVSEAAAATQGHTASRKSKGAKQGQHNSQHHSHS--PLEQHSQP--PPPVPQHQEPPPERLSPAPLTHPPHPERASTTRHSSEDSDITSLIEAMDKDFEHHDSPSLDVFTEQPPSPLSK-----NKGKGKSLQQRKAKPPKKQEEKEKRGKGKPQEEELKDTLAD-DDSSSTTTETSNPDTEPLLREDTEKHKGRPAMP----EKQESELSQGKPKSKKLLNAKKEIPTDVKGGSFELPYTPSLENKQRRSLS-KIPLPTTLTSGSKSRNPQKTKGTDKLVGSRPAALSKLLPNS--QELSSTSSSEGEKDSPPPEWDAVPVHKPSSSTDSLYKLSLQTLNADIFLKQRQTSPTPASP-LPTAPCPFTSRGSYSSVVNSSGS-DTKAKQPNGSKSKLTKAASLPGKNGNPTFAAVAAGYDKSPGGNGFAKISSNKSEFSSSLGISHIP-VDSDGSDSSGLWSPVSNPSSPDFTPLNSFSAFG--NSFNLTGAVFSKL--SRSCSQSSQRSWNELSSGPSYLWDAPAADPSPSWPVPASSSSTTHTATSILGNTSGLWSTTPFSSSIWSSNINSNLPFSTPTNTLSGIGLMGTENSTPAHAP-ASSPADDLGQTYNPWRI-WSPTIGRRSSDPWSNSHFPHEN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70472-1", "uniprot_id": "TM131_MOUSE", "id": "O70472-1", "name": "Transmembrane protein 131", "aln": "MGKRAGG--AAAAAAAASTSSAAGLEPAAGRGGGPRSAAAGLLGALHLVMTLVVAAARAEKEAFIQSESIIEVLRFDDGGLLQTETTLGLGSYQQKSISLYRGNCRPIRFEPPMLDFHEQPVGMPKMEKVYLHNPSSEETITLVSISATTSHFHASFFQNRKILPGGNTSFDVVFLARVVGNVENTLFINTSNHGVFTYQVFGVGVPNPYRLRPFLGARVPVNSSFSPIINIHNPHSEPLQVVEMYSSGGDLHLELPTGQQGGTRKLWEIPPYETKGVMRASFSSREADNHTAFIRIKTNASDSTEFIILPVEVEVTTAPGIYSSTEMLDFGTLRTQDLPKVLNLHLLNSGTKDVPITSVRPTPQNDAITVHFKPVTLKASESKYTKVASISFDASRAKKPSQFSGKITVKAKEKSYSKLEIPYQAEVLDGYLGFDHAATLFHIQDSP---ADPVER--PIYLTNTFSFAILIHDVLLPEEARIMFQVHNFSQPVLILPNESGYIFTLFFMPSTSSMHIDNNILLVTNASKFHLPVRVYTGFLDYFVLPPKIEER-----------FIDFGVLSATEASSILFAIINS-NPIELAIKSWHIIGDGLSIELVATERGNRSTVIASLPELERSSLPDQSPVTLASGHFAVFRVKLTAKKLEGVHDGAIQITTDYEILTIPVKAVIAVGSLTCFPKHMVLPPSFPGKIVHQSLNIMNSFSQKVKIQQIRSLSEDVRFYYKRLRGNREDLEPGKKSKIANIYFDPGLQCGDHCYIGLP-FLSKSEPKVQPGVAMQEDLWDADWDAHQSLFKAWMGIKENAGHRLNAM-FEVNTDLQKNIVSKVSAELSWPSVLSS-PRLLKFPLTNTNCSSEEEISLENPADVPVYVQFIPLALYSNPSVFADKLVSRFNLSKVAKLDLRT--LEFQVYRNSAHPLQSPTGFTEGLSRHFILNLILKPGEKKSVKVKFTPLHNRTVSSLIIVRNNLTVMDAVMVQGQGTTENLRVAGKLPGPGSSLRFKITEALLKDCIDRLKLREPNFTLKRTFKVENTGQLEIRVETIEISGYACEGYGFKVVNCQEFALSANASRDIVILFTPDFTASRVIRELKFVTSSGSEFVFVLNASLPYHMLAACAEALPRPNWELALYIIISGVMSALFLLVIGTAYLEAQGIWEPFRRRLSFEASNPPFDVGRPFDLRRIVGISSEGNLNTLG-CEHSHGRGFYSN--ASSRPGTGSHRQCGTSVHPHSSHGSKNSADVDNVRTRNSSSMSSRTSPQAAASQSTSKTSPLVSETAAATQGHTASRKSRGAKQGQHSSQHHSHSHSPLEQHSQP--PPPVPQHQEPPPERLSPAPLTHPSHPERASTTRHSSEDSDITSLIEAMDKDFDHHDSSPLDVFTEQPPSPMSK-----SKGKGKSLQQRKAKPPKKQEEKEKRGKGKPQEDELKDALAD-DDSSSTTTETSNPDTEPLLREDTEKHKGRPAVP----EKQESELSQGKPKSKKLLNAKKEIPTDVKGSSFELPYTPSLENKQRRNLPTKIPLPTTLASGSKSRNPPKTKGTNKLVENRPVALSKFLPSS--QELGNTSSSEGEKDSPPPEWDAVPVHKPSSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSLPTAPCPFTSRGSYSSVVNSSGS-DTKAKQTSSSKSKLTKAASLPGKNGNPTFAAVAAGYDKSPGGNGFAKISSNKSDFSSSLGISHIP-VDSDGSDSSGLWSPVSNPNSPDFTPLNSFSAFG--NSFNLTGAVFSKL--SRSCSQSSQRSWNEFNSGPSYLWDSPATDPSPSW--PASSSSPTHTATSILGNSSGLWSTTPFSSSIWSSNINSNLPFSTPTNALSSISLMGTENSAAAHTPSASGPADDLGQTYNPWRI-WSPTVGRRSSDPWSNSHFPHEN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92545-1", "uniprot_id": "TM131_HUMAN", "id": "Q92545-1", "name": "Transmembrane protein 131", "aln": "MGKRAGGGATGATTAAVSTSAGAGLEPAAARSGGPRSAAAGLLGALHLVMTLVVAAARAEKEAFVQSESIIEVLRFDDGGLLQTETTLGLSSYQQKSISLYRGNCRPIRFEPPMLDFHEQPVGMPKMEKVYLHNPSSEETITLVSISATTSHFHASFFQNRKILPGGNTSFDVVFLARVVGNVENTLFINTSNHGVFTYQVFGVGVPNPYRLRPFLGARVPVNSSFSPIINIHNPHSEPLQVVEMYSSGGDLHLELPTGQQGGTRKLWEIPPYETKGVMRASFSSREADNHTAFIRIKTNASDSTEFIILPVEVEVTTAPGIYSSTEMLDFGTLRTQDLPKVLNLHLLNSGTKDVPITSVRPTPQNDAITVHFKPITLKASESKYTKVASISFDASKAKKPSQFSGKITVKAKEKSYSKLEIPYQAEVLDGYLGFDHAATLFHIRDSP---ADPVER--PIYLTNTFSFAILIHDVLLPEEAKTMFKVHNFSKPVLILPNESGYIFTLLFMPSTSSMHIDNNILLITNASKFHLPVRVYTGFLDYFVLPPKIEER-----------FIDFGVLSATEASNILFAIINS-NPIELAIKSWHIIGDGLSIELVAVERGNRTTIISSLPEFEKSSLSDQSSVTLASGYFAVFRVKLTAKKLEGIHDGAIQITTDYEILTIPVKAVIAVGSLTCFPKHVVLPPSFPGKIVHQSLNIMNSFSQKVKIQQIRSLSEDVRFYYKRLRGNKEDLEPGKKSKIANIYFDPGLQCGDHCYVGLP-FLSKSEPKVQPGVAMQEDMWDADWDLHQSLFKGWTGIKENSGHRLSAI-FEVNTDLQKNIISKITAELSWPSILSS-PRHLKFPLTNTNCSSEEEITLENPADVPVYVQFIPLALYSNPSVFVDKLVSRFNLSKVAKIDLRT--LEFQVFRNSAHPLQSSTGFMEGLSRHLILNLILKPGEKKSVKVKFTPVHNRTVSSLIIVRNNLTVMDAVMVQGQGTTENLRVAGKLPGPGSSLRFKITEALLKDCTDSLKLREPNFTLKRTFKVENTGQLQIHIETIEISGYSCEGYGFKVVNCQEFTLSANASRDIIILFTPDFTASRVIRELKFITTSGSEFVFILNASLPYHMLATCAEALPRPNWELALYIIISGIMSALFLLVIGTAYLEAQGIWEPFRRRLSFEASNPPFDVGRPFDLRRIVGISSEGNLNTLS-CDPGHSRGFCGAGGSSSRPSAGSHKQCGPSVHPHSSHSNRNSADVENVRAKNSSSTSSRTSAQAASSQSANKTSPLVLDSNTVTQGHTAGRKSKGAKQSQHGSQHHAHS--PLEQHPQPPLPPPVPQPQEPQPERLSPAPLAHPSHPERASSARHSSEDSDITSLIEAMDKDFDHHDSPALEVFTEQPPSPLPK-----SKGKGKPLQ-RKVKPPKKQEEKEKKGKGKPQEDELKDSLAD-DDSSSTTTETSNPDTEPLLKEDTEKQKGKQAMP----EKHESEMSQVKQKSKKLLNIKKEIPTDVKPSSLELPYTPPLESKQRRNLPSKIPLPTAMTSGSKSRNAQKTKGTSKLVDNRPPALAKFLPNS--QELGNTSSSEGEKDSPPPEWDSVPVHKPGSSTDSLYKLSLQTLNADIFLKQRQTSPTPASPSPPAAPCPFVARGSYSSIVNSSSSSDPKIKQPNGSKHKLTKAASLPGKNGNPTFAAVTAGYDKSPGGNGFAKVSSNKTGFSSSLGISHAP-VDSDGSDSSGLWSPVSNPSSPDFTPLNSFSAFG--NSFNLTGEVFSKLGLSRSCNQASQRSWNEFNSGPSYLWESPATDPSPSW--PASSGSPTHTATSVLGNTSGLWSTTPFSSSIWSSNLSSALPFTTPANTLASIGLMGTENSPAPHAPSTSSPADDLGQTYNPWRI-WSPTIGRRSSDPWSNSHFPHEN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BDB2-1", "uniprot_id": "A0A8M2BDB2_DANRE", "id": "A0A8M2BDB2-1", "name": "", "aln": "--------------MASKDTTQSSLHPTR-----TKSACVGLL---RLLFIAFIHVAQANKQAFIQSDNILEVLHFGDGSLLQTESDIDLSSYRQKSASSQRGNSRPIRFEPPMLDFHEQPVGMPKMEKVYLHNPSSEE-ISLISISATTSHFHASFFQNRIIPPGGNTSFDVVFLARVVGNVENTLFINTSHHGVFTYQVFGVGVPNPYRLRPFVGARVPVNSSFSPLISIFNPHSEPLQVVEMYTSGGDLHLELPTGQQGGTKKLWEIAPFETKGVMRASFSSRDADNHTAFIRIKTNASNEDEFIILPVEVEVTTAPGIYSSTEMLDFGTLRSQDRPKQLNLHLLNSGAKDVSIMSVRPTPSNEAVTVEFKPITLKAGESRYTKVASISFDASKARRSDQFSGKITVKAKEKSYSKLEIPYQAEVLEGYLGFDHTATLFHIRDSP---VDPVDR--PIYLTNTFNFAIRIHNVSLPEEAKTMFNVHNFSTPVLIPPHESRYIFSLLFRPVRPSIHIDSNILLITNASKFHLPVRAYTGFLEPVVLPPCLQEH-----------ILDFGVLSATDTSSLVFVVVNS-NPIELEIKSWLVTGDSLSMELLNTERGNRSIALSRIQELQNTSAAQYKTVILASGYYAAFKVTLVAKALEGIYDGAVHITTDYEILTIPVKALIAVGTLSCSPKHIILPDAFPGKVVHQGLSIQSSFSQKVRLQQIRSLTEDVRFQYKRVRNNKVELEPRRKSKIANIYFDASLQCGDHCYVGLP-FVLKSESRPH-GLVMQEDMWDADVDLHQRLLKRWRELKEQSGHEVEAF-FEVDTDLQKNVQAKISAKLKWPSLLNSTLQQIHFPLTNTNSSSEEEVILENSADVPVYVQVLPLALYPNPSVFTGKLADRFPLGKLSNINLDTNTLEFLVQKNHSSVMKSSTGFVEGSTRPYVYNMLLMPGEVKSFNVRFRPTTNHSVSSLLVVRNNLTIVDLIMVHGQGTTESLRLAGKAPGLGSSLRFKLTESFLKDCS-EVKAKEPNFTLRRTFRLENTGLLPIHIRSVEISGNACEGYGFKVLNCEEFALKPNTSKDLIILFTPDFTSSRVIRELKLVTAGGSVFAFVLNASLPYHMLAVCAEMLPRPNWELELYIIVSLVMSSMFLLVIATAYLEAQGIWEPFKRRLSVES-NSPMETGKPFDLREIVRIQSDPNLNDFADSNQNSTRGMYGS----SIGGRAGGRQSG-------SHSSSNS---------NGVLPDSKPRSGSGRSGSMQSSSTFSLKDNGPGLNQVTNRKARSSKQQQQGSG------------------------------LLEDLPSTGPSQSN--SARVNSTEDQDYNRLLVAMDKDLDRPESPAINVSSEHNSQQSSQNKVLESKGKNETKVKNKTKALKKKEEKERKTKGKTQGEDFKEPLADNDDSSSTTTETSNPDVEANIKEEPVKVKGKTVAIDNGKEREEITPSPTKPKSKKQPTTKKENPVE-KSSSLELPYVTPLE-KQDKRKNFKTLASTAIPGVSKPRALSKLVN-AKMGDDRPSPLGKFVSNGSMPELGHSSGSEGEKESPPPEWD-VPLNKNGNQADSLQQISMQTMHADPFLKGPSSVINRTCSPPPTSPS-LVPHGSYSSMMHPSSE----INLKKAPGNKLTKSASLPGQNGNPTFAAVAAGYDKSPGGSGCASKADG----LGKVALPHMTSVESDGSDSSGLWSPVDSTSSPSFNQVNAFSAFGPNNPLNLSG-VFRGMTVPKSSE--SQQSWPEYTPVSPSIWDTETDN---SW--TTITGSPATPTTSILGSARSPWS---FSSSIWSTGNDSTLHSFSPPATSTLPDLVS-------HTAPPTPAPNDMGRTYNPWSMGWSPSLNRWNSEPWPNSPDNNNGI---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V7H4-1", "uniprot_id": "TM131_DROME", "id": "Q9V7H4-1", "name": "Transmembrane protein 131 homolog", "aln": "--------------------------------------------------MPTQVQMRPLLRIFAEPILLILIFLFTLGAKGEKVLQETFLGLQEAPIHDLG----DLRLVPSRLDFGTWSVGQARSQTVTLFNQHSNRTLQLNAVAGPSPAFYSSFLGTREVPPQGNTTFNVVFLPRQLGAIAADLLIHTS-FGQAELAVQGEGSECPYRLKPLVGIKAPMNATLTPEIHMYNPHERPLQILEIYSSGGEFQLELPSGGSEGPQNLWKIPPHTLKPVIRISFHGRTAGNHSAYIRIKVAEQELD--IFIPVEFEILPRHSVYARNPLADFGRVATLNAPDALQFKLDVRNDESRQLFGSYLR--------QIPGLSFDANNTSIVLDASL-FEGDEIINDLLVINSNQSSTSPGADQPFTVLVRAEIFHGGLTFDRNATRFVTTSPEGVEGEPLERKRSLVVRNKFAIPLMLFNVSLTEPIDESILEVTLVGDPRILIQPDESVELLRLNLLNDQVPFKSFLRIETNVTVFKLPLVSCSGRLHVSTQPIVLNFRQESLEKAAYNLELDLGTVPFAEMSRDGFVILRNDNPVPVRITNWFFKHP-KTVYSQSTFLGCRATAIGHPVSVENDTKGWHLCTEIRAGESAVFKVAIQTYEADATFG-TLKVWTPYEVIRVRVKFEASVGHLEIDQEQLSFKNCFPGKMCTAVLSIRSSFTHPVHVKGIS-FALPVGLRFKDFNAKGTTIAPQTLTKVGRIYFDPASVCRNNCYIRESTNDLAIFPSVPGGGNGNSGVINNNLLYDGVELRQRTELFRQLRRQLSSMSLTLHSEELPPLELDFSITIEWP-------KLVQFQPIPPTPAIEVGQVQR---------QWITLTNPSQSPLLLDYFLSDPAFARRTQLSLPH---EVIDVSSTSCYLTDKEVFSLPEAG---DPILLPGGASLTIPITFSAQLPEKYCTLLHVRSNLTLYEAVWLQARAVQSQFRFGNRRPGAASPLLFEMATNQFQGCQ----SGNEAVVVTRSFTARNSGVIPIRIEGFLIGSLPCEDFGFKVMDCAGFDLGENEARKVEIAFSADFTTSAVKRSLTLLTNLTYDISYKLLAQMPAESVELCASLLVRPGWESSLKNAALVVLLASFGLVLVAAVFDAKAIMVQQN---AYDAARNKGPLQPTFNLRNIVKLQAEEAAAKAESVQQQQK-------------------------------------------VKNGQLKELRKRTVVNSTNSKSKS----------------------------------------------------------------------------------KSSWSPWSMDMNALSKHLQKAKPKTVVSTPVTPPAASAP--------AAAPVPLPEAKPVKKSSTPSPQGVPISVQVRPQKKVKP-TPAVVLGTTKPKQEVSTPVADQHEKSLAKSSPP----QQENISPKPNKPPEQRVLKEQ---------------------------------------------------------------------NGSAKKMGKTPGRERERERRSKDQKLTNGTGAGVGFRKPERKQRQKLNFGQTTNSTSPPESPDALKCISNPWETSSRVSFRDVLR------------------------------TPQMAPTDNGFDWNHATS------------SSDLGPIGDNRKNATPPMVTSLWEPLSATASNSLFANTEVDFIT-----------------PDAIYEQREREKPQWEQRSDLVMRQQLLLQQPQKLEFQLRQQEKISLLANMDPSNWATNWSPLGYSTWPNATAGIGVMRPPPGLEQSARQTHNLAQEQVSAGPASGTGAALHGESLPTQYDPFTSPSSIWSDTWRQSSQRNNHNHMN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . * :. :: :: * *. :. : . :: . :*: *. *** .** .: :.* *.* *:. : * :::..:. *::**: .* : * ***:*:****.* :* : *:*:** .* * * * ****:*::* :.*:*::::* * :.***..***::*:*:***:::****:* . *.::**:*.*. * *:* ** .* *.**:*:****. .: *::***.*: . .:*: . : *** : : : *. *:::* . :. : . .: :::.*.:: . **: *:... . . .. .:. : . : : :**::.* * **: ** * .. :*::* .: : *.* :.: :.:* *.* : .: * : . : * : .: :.. : : **.: *:**: :* *. . * :: : :*:*.:. :: * *.::.. **: : *..* . :: . * *: :. ..:. : . : :* *.*:* : : :. .. :::: * **:: : ** :** * ::: : .****: *.: .**:: *::: * :: * : :: .. : : * :*:..****.. * ::**: . . * :..: : : . :: : .: :.:.:: : :.:: : ..: :.** : ::* .. : * . * :.*: .:..:: . : . :.: :::.* *. . : : . * : ::* * :. : * . .. .:*: **.***: : : ::.:.. ..:*...: ** .*.* *::: ::.* : ..: *:* .*:* : *::. . *.. .**.:****::* * * * ::.: * *:.***:* * *.*.::* : : * *.:* . : **. * **.** * :: : * **: :* ::*:.* . : :: . .*:**.** :.:: : *. . : . : * ..: .:. . . : *:.*.::: .. .: . . . . :.*. **.. . : . :. : : * ..: :... : :: * .: ::.: . * .:: . : .. ::. :.. * *:: . : . . . . : . *.:: . : .. . . : * .: *: .::. .* :*.. *:* . . . ..:. :: . :.**.*:. . * .: . .. : . : ::. : . : . . . : :. : . :. * *.. . .*. : .: . : * .: . *:.* :* :: ", "identical_positions": 270, "similar_positions": 577, "identity": "13.98%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-666", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P32305-1", "uniprot_id": "5HT7R_RAT", "id": "P32305-1", "name": "5-hydroxytryptamine receptor 7", "aln": "-------------------------MMDVNSSGRPDLYGH-LRSLILPEVGRGLQDLSPDGGAHPVVSSWMPHLLSGFL---EVTASPAP-TWDAPPD------------NVSGCGEQIN-YGRVEKVVIGS-----------------------------------ILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDK---VCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVQ-----------------------PESVISLNGVVKLQKEVEECANLSRLLK---------------------HERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAA------GMHEALKLAERPERSEFVLQNS----------------------DHCGKKGHDT------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P32304-1", "uniprot_id": "5HT7R_MOUSE", "id": "P32304-1", "name": "5-hydroxytryptamine receptor 7", "aln": "-------------------------MMDVNSSGRPDLYGH-LRSLILPEVGRRLQDLSPDGGAHSVVSSWMPHLLSGFP---EVTASPAP-TWDAPPD------------NVSGCGEQIN-YGRVEKVVIGS-----------------------------------ILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDK---VCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFSGFPRVQ-----------------------PESVISLNGVVKLQKEVEECANLSRLLK---------------------HERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAA------GMHEALKLAERPERSEFVLQNC----------------------DHCGKKGHDT------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P34969-1", "uniprot_id": "5HT7R_HUMAN", "id": "P34969-1", "name": "5-hydroxytryptamine receptor 7", "aln": "-------------------------MMDVNSSGRPDLYGH-LRSFLLPEVGRGLPDLSPDGGADPVAGSWAPHLLS------EVTASPAP-TWDAPPD------------NASGCGEQIN-YGRVEKVVIGS-----------------------------------ILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVTDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAKMILSVWLLSASITLPPLFGWAQNVNDDK---VCLISQDFGYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFPGFPRVE-----------------------PDSVIALNGIVKLQKEVEECANLSRLLK---------------------HERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQCQYRNINRKLSAA------GMHEALKLAERPERPEFVLRACTRRVLLRPEKRPPVSVWVLQSPDHHNWLADKMLTTVEKKVMIHD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PVG7-1", "uniprot_id": "A0A8M9PVG7_DANRE", "id": "A0A8M9PVG7-1", "name": "5-hydroxytryptamine receptor 7", "aln": "-----------------------MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGG-----------------------------------VLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDR---VCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEE----VEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVG---------------RRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAA------GMHEALRLVERPE---VVVSG---------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P20905-1", "uniprot_id": "5HT1R_DROME", "id": "P20905-1", "name": "5-hydroxytryptamine receptor 1", "aln": "MALSGQDWRRHQSHRQHRNHRTQGNHQKLISTATLTLFVLFLSSWIAYAAGKATVPAPLVEGETESATSQDFNSSSAFLGAIASASSTGSGSGSGSGSGSGSGSGSYGLASMNSSPIAIVSYQGITSSNLGDSNTTLVPLSDTPLLLEEFAAGEFVLPPLTSIFVSIVLLIVILGTVVGNVLVCIAVCMVRKLRRPCNYLLVSLALSDLCVALLVMPMALLYEVL-EKWNFGPLLCDIWVSFDVLCCTASILNLCAISVDRYLAITKPLEYGVKRTPRRMMLCVGIVWLAAACISLPPLLILGNEHEDEEGQPICTVCQNFAYQIYATLGSFYIPLSVMLFVYYQIFRAARRIVLEEKRAQTHLQQALNGTGSPSAPQAPPLGHTELASSGNGQRHSSVGNTSLTYSTCGGLSSGGGALAGHGSGGGVSGSTGLLGSPHHKKLRFQLAKEKKASTTLGIIMSAFTVCWLPFFILALIRPFET----MHVPASLSSLFLWLGYANSLLNPIIYATLNRDFRKPFQEILYFRCSSLNTMMRENYYQDQYGEPPSQRVMLGDER-------------------------------HGARESFL-------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : * : .: . . . : :... : . . . . . * * : . :*. :* :: * *: ** ** *:**:*:***:*.***:*****:**.**: ***:. : ::: :* ** ::*::::::**:******:.**.**:****.**:** * *::. * : *** :*.*:****: .:: :*:. :* :.*:*.* **:* :****::***.:**:*::**: . :.. . : . . . : . . *. *. .:: : :*:**::****::.***:******:*: *** :* :. *********:**:*** :***:*..::.:* : .:* : * : :: * ", "identical_positions": 135, "similar_positions": 137, "identity": "22.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-667", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L291-1", "uniprot_id": "A0ABK0L291_RAT", "id": "A0ABK0L291-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCQEG--LSRLALSSPRKQTACSLGERRTLTEALEPVDCTLEYGRHPSSSLQKEFPQHQGDDQNKD--AVPQDRLLR---EVACRAQKLEALLEEIHR-------GAQEP----------REEEREQRKLGDALENARLEIEKLKDNLTKLK-------------------------------------------------ESGTTDLQKAKEHNQR-----LDEEILALRNRVRSLDS----------EKKVLGEMYLTSGEKASYQHQGELRELRQNLHRLQILSNSAEKELRYERGRSLDLKQHNSLLQEENLKIKIELKQAQEKLLDNARMHSSLMAEWKLCQQKVKELELEGLRQTQSIKSQQGLQEKLAREKSKTAEAQEKILDLQQKLDHAR-QVCLSDVCILRRKQLEEEIKEAKSTEARLKQQCQEEQQRRILLDQDVNELQRQVRTLQDKESQQEAANSQQQ------ETLRKQLEIERRKCEEYVKSNQE----LSEKLASLQQEKEALWHEHGQFLEQLGDHVRNYKDKHHCHKAKLQKVKDRLTLELEIRNKRIKELEDDTGKLQQKIEMEKVFQGQIMTQNDILLLEKRKLLEQVTNQEELICSNKSTISAFQSKTFLLDKENQQLQENCLRLMQQISLLEQIIRSIQIRREE-------------------------------------------------------------ETVITDNAAFEILKKILPLQNSSFSGTGLVLPAKNPKEETELLKSEGATVMAKSPEPPSQ----SQDSENGYINVTSLKETYHTQ-GDRKPKL--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BVF4-1", "uniprot_id": "CCD30_MOUSE", "id": "Q8BVF4-1", "name": "Coiled-coil domain-containing protein 30", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCQEG--LFRLALSSPRKQTACSLGERRTLAEALGLVDSTLESRRDPNSSLQKEFPQHQDEDQSRA--AAPQDCLLR---DVECIAQKLEASLEEIHR-------GAREP----------REE-REQRTLGDALENARLEIEKLKDNLMKLK-------------------------------------------------ESGTTDLQRAREHNQR-----LDEEILALRNRVRSLDS----------EKKVLGEMYLTSGEKTSCQHQGELRELRQNLRRLQILCNSAEKELRYERGRSLDLKQHNSLLQEENIKIKIELKQAQEKLLDNARLHSSLTAEWKHCQQKVKELELEGLRQTQSLKSQQGLQEKLAREKSKAAEAQEKILDLQQKLDHGR-QVCLSDVCILRKKQLEEEIKEAKSIEARLQQQCQEEQQRRILLDQDINELQTQVRALQDKEEQQEAVNSQQQ------EALRKQLERERRKCEEYVKSNQE----LSEKLSNLQQEKEALWQEHGRFLEQLGDHVRNYKDKHHCHKAKLQKVKDRLTHELEIRNKRIKELEDETGKLQQKIEMEKVFQGQIMAQNDILLLEKRKLLEQVTDQEELICSSKCTISAFQSKASLLDKENQQLQENCLRLMQQIGLLEQIIRSIQIRREE-------------------------------------------------------------ETVITDNAAFEILKKILPLQNSSFSGTGFVLSAEN-LQETELHKWEGAAAIPKSPEPLSR----SQDSESGYINVTSLKETHNTQ-GDQKPEL--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VVM6-1", "uniprot_id": "CCD30_HUMAN", "id": "Q5VVM6-1", "name": "Coiled-coil domain-containing protein 30", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQEKNEMFESEWSKEREREKQLASGLDTAEKALKVESEELQKSKSELICLYNEVHNLPGESESKDHFLIACDLLQRENSELETKVLKLSQEFAQLNHFTLG---GKTAPSNLITSENTCKDPESNEPILETEIQSRKEETEELCPKLGERKQKEIPEESVKEGSFPREGQK-----------------------------EEGSQQNRDMKDEEKEQQLTMKPEEIVRLREELSHINQSLLQSQSSGDSSDDSGAQHPSSGEKLKYNQQGEVQQLHQNLHRLQILCNSAENELRYERGQNLDLKQHNSLLQEENIKIKIELKHAQQKLLDSTKMCSSLTAEYKHCQQKIKELELEVLKHTQSIKSQNNLQEKLVQEKSKVADAEEKILDLQRKLEHAH-KVCLTDTCISEKQQLEEKIKEATQNEAKVKQQYQEEQQKRKLLYQNVDELHRQVRTLQDKENLLEMTCSQQQSRIQQQEALLKQLENEKRKYDEHVKSNQE----LSEKLSKLQQEKEALREEYLRLLKLLNVHVRNYNEKHHQQKVKLQKVKYRLTNEVELRDKRINQFEDEIGILQHKIEKEKAIQDQITAQNDTLLLEKRKLQEQVIEQEQLIHSNKWTISSIQSRVLYMDKENKQLQENSLRLTQQIGFLERIIRSIHIRRGENLKEFPVPKWWHRGKLASLPPTKKQKEIYSTEVFTSNNAELQHEDESVPEATEKWKHSEQMETTISDILESEVVNEILPLSNSSFSGKGLVESFAS-LQETEEIKSKEAMASSKSPEKSPENLVCSQNSEAGYINVASLKETHGIQEQDQKSEL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IL38-1", "uniprot_id": "A0AC58IL38_DANRE", "id": "A0AC58IL38-1", "name": "", "aln": "MEKREEKEQDELSVRLQRDGVSPEASGEERERHLWVLLQHSESSLSTATEDLQTLRTQQASEMREVENYVEHIRNMLEERESLTAEYERDNEKLRSELALMKHQQDSQCKEVVEMLEQEGLAEISQSSASEQVAYLLVERATLLERLEAAERKLDTQTLTGNLREVHLQEELDHIRHTLEEELGQQKENMNKESTVQSPWKKFFGVRKATLRVQNLPVHGEELGRERKRLERDLEEASNRLAMAHKEIRHLTDELDVARKVQNFCAPDLQKTGEEVEQLKQEVDKLKQCDMVELQKAKERNERLDGEIRVLRDRVRSLDTERRTLLKLVEQSNLHSTQGISVSLEHNKIQSIQSVGNNVNRDSSLAEEDEILHKRCRRESEDKDSRLRELERRLQKQQREHEDLVERNEELEALLGEAQNTTKDEREHHECEIEGLQRKIKSIEEELRKRDNKKVEKKDEDLFRGTDSEISESIQERLKFLESRLTEEKGWRKQLEVDLSVAKAALKKEKEVMQRDHEELKRLRVEVQRLEVECRQGKTLNKNLTQVKGEKGILEEKVAQLERAQSRIQDDLTLQKENSQAEEDLRDSRGQVAELKSMVDKLRTELTRLEKEHNTLRDELMEKRGLVLQLQKELSEKAHERLQTDGEKERLSLELLHLQQQLQYTREQIPRSAQEHTANHKATAQNEGSCQLACVKSEVSKLHSTLEEERQLASQHQLALQAQIAEAQSRVKAQDSLLQQKGEENKQLKQDLQRTQHLFTSAERELRYEREKNLDLKRHIALLDQEKVKLCAELKQAQAKVAQHEGNAAGQVAELERLQQRARDLELEMARSSQNRQTNSSLMDELNSQRSRVIAADKKVVELQQQLKNALHQLRLEEARSGETSKLERDTRDMSDNLSALRAHLQEEQLQRKLLEQKDEELQQHVRSLRAKEASLVRTNLEISHRVQELETRLQVMESELNTAREEQRSGQKSCHRLEEQLLSAQHESERLQEELKLVVQQLDTNVRRYNEKQSQQKTKLRRAKQIFMKTVSQHEQRIQQLENDLALATSLSEKEKDWIRTVTEENEQLLLERRELLQRISEAEEMGNNGLRTATTTQQRVKFLEMENKQLQEKTLTLANQIGILDRALRNLQSVCTVEEVKKMFPSGAHQDGLLRTSTPSPQPGLCDSWG---------------------------ILDAIRRVKVGESGVKSMEISSSVPVSQSTEIGYLNLTSPLTPNSRGRTAGIKVIILPEMEIWHYFTHPYATQENHRSEQNTFEWKRNTGGGSSDE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : . :. : . ** . :: : * *. . : .. : : . :*. .:: . : * : . * : * :* : : :. : : : :.: .*: *:. : . . . .: :. :: * ::*:*:*:* * * .***.****** :.****:* :**::*::*: ***:** *: : :. ** : **: ::**** : :*. :::..* ::* ::*:. *::*:::**::*.:. :: * :. . .:**.. :: .. : :: : **** :* ** *. :**: :**:*: ** . : . *: : :* * .. * :*.*: *.*:* . *:*.* * .* .:: *. :**.*::*: :*.**::.* : :. :::**:::*:: . * ** : :*: ****:*:* ::: : *:: .. * :: *.:. :: **:****: * * :**.:*:: :*.:: .* * : : :..* . . . . . : . .. * * ::*. : . ", "identical_positions": 136, "similar_positions": 220, "identity": "10.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-670", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NQS3-1", "uniprot_id": "NECT3_HUMAN", "id": "Q9NQS3-1", "name": "Nectin-3", "aln": "MARTLRPSPLCPGGGKAQLSSASLLGAGLLLQPPTPPPLLLLLFPLLLFSRLCGALAGPIIVEPHVTAVWGKNVSLKCLIEVN--ETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAICIAATGKPVAHIDWEGDL-GEMESTTTSFPNETATIISQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISDPPTTTTLQPTIQWHPS----TADIEDLATEPKKLPFPLSTLATIKDDTIATIIASVVGGALFIVLVSVLAGIFCYRRRRTFRGDYFAKNYIPPSDMQKESQIDVLQQDEL-DSYPDSVKKENK----NPVNNLIRKDYLEEPEKTQ-WNNVENLNRFERPMDYYED-------------LKMGMKFVSDEHYDENED-DLVSHVDGSVISRREWYV----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JLB9-1", "uniprot_id": "NECT3_MOUSE", "id": "Q9JLB9-1", "name": "Nectin-3", "aln": "MARTPGPAPLCPGGGKAQLSSAFPPAAGLLLPAPTPPPLLLLLIPLLLFSRLCGALAGSIIVEPHVTAVWGKNVSLKCLIEVN--ETITQISWEKIHGKSTQTVAVHHPQYGFSVQGDYQGRVLFKNYSLNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIKGPDSLIDGGNETVAAVCVAATGKPVAQIDWEGDL-GEMESSTTSFPNETATIVSQYKLFPTRFARGRRITCVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKGVNLKCNADANPPPFKSVWSRLDGQWPDGLLASDNTLHFVHPLTVNYSGVYVCKVSNSLGQRSDQKVIYISDPPTTTTLQPTVQWHSS----PADVQDIATEHKKLPFPLSTLATLKDDTIGTIIASVVGGALFLVLVSILAGVFCYRRRRTFRGDYFAKNYIPPSDMQKESQIDVLHQDEL-DSYPDSVKKENK----NPVNNLIRKDYLEEPEKTQ-WNNVENLTRFERPMDYYED-------------LKMGMKFVSDERYNESED-GLVSHVDGSVISRREWYV----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58HC72-1", "uniprot_id": "A0AC58HC72_DANRE", "id": "A0AC58HC72-1", "name": "Nectin cell adhesion molecule 3", "aln": "MAEEVR----------------HFFGNTTLFRR-----LLPLLG--FLFSACDGVWSNQVVVPAQVTSVLGKNVTLSCRMEMSSNLSLTQSSWERHLPSGIITLAVFNPVYGTSVADEYSRRVHFLKPSVHDVSIVLQGVGFADIGMYTCKMVTFELGNMQASTNVDVMVEPKVYVSPGSLSLTADDGETLVATCTAERGRPAAEVFWESDLPGQTAVVTQSEPEGTTTTLVHYVLAPTRASHGRSLSCVVRHPALSRDFRIPYRLNVFFVPDVMVIGGKNVWYVGQKDVQLDCKANANPPALFYLWTRLDALMPAGVNMHNGSLVFTRPLEATDSGQYRCEVQNDVGQNFHDVPFLVLDPPPTTAAPTTTTTFSKSLHPDTSLTITAPINQRAHFSSPTRSSPRDADLSTLVGGIVGGILILVLLLALAGAFYMRRRRTFRGDYYTKQYIGPSDMQKESQLDVLEPHELQDVYGDDSGNGSQDLKPKPEGDIIYPDYPNDHKDTEGWG--DNLS-LQREASYYSDHHNHHNVNPSGPPLHNGSPYLRDECFDNATDNDYVSHIDGSVISRREWLRSLFIRRHHSRMNHQLFQHIFCTADALPAATHYWKTSIHTHSHTYTLANLKYSIHLHSHVFRLWGKPRAPRRNLRKHVENMQTGPAGTRIMTFLL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. . *: ** ** :*** *. :. ::* .:**:* ****:*.* :*:. ::** ***: .. *:**.:* ** ** .:*. ** * : *::*.:*.*:.:**:* * * ** *** *** *:**.* *:***.* : *. ** ...**:.* * * *:*.*.: **.** *: * * *: *:* : :* * *** ::** ::***:****.:*:* .: *:: :.*:* * * .. *:**:*.*:*.*:*:****.: :*:***. * *: :.:* *.:** . ** * *:* *.:**. .: : : ***.**: .* ... :.: *. :: *. .* :: :* :.*::..:*** *::**: *** * **********::*:** *********:***. .** * * *. : .: :* .::* ** :: :.*: *. :**. ::* .**.* *: * :: ** ::: * . ***:********** ", "identical_positions": 218, "similar_positions": 164, "identity": "32.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-671", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60677-1", "uniprot_id": "ITAE_MOUSE", "id": "Q60677-1", "name": "Integrin alpha-E", "aln": "MKWLFHTLLCMASLKPQGAFNLDVDWAWVTALQPGAPAVLSSLLHQDPSNNQTCLLVARRSSNRNTAALYRCAISISPDEIACQPVEHICMPKGRYQGVTLVGNHNG-VLVCIQVQARKFRSLNSELTGACSLLTPNLDLQAQAYFSDLEGFLDPGAHVDSGDYCRSKGGSTGEEKKSAR--RRRTVEEED---------EEEDGTEIAIVLDGSGSIEPSDFQKAKNFISTMMRNFYEKCFECNFALVQYGAVIQTEFDLQESRDINASLAKVQSIVQVKEVTKTASAMQHVLDNIFIPSRGSRKKALKVMVVLTDGDIFGDPLNLTTVINSPKMQGVVRFAIGVGDAFKNNNTYRELKLIASDPKEAHTFKVTNYSALDGLLSKLQQHIVHMEGTVGDALQYQLAQTGFSAQILDKGQ---VLLGTVGAFNWSGGALLYSTQNGRGCFLNQTAKE--DSRTVQYSYLGYSLAVLHKAHGVSYVAGAPRHKLRGAVFELRKEDREEDAFVRRIEGEQMGSYFGSVLCPVDIDMDGTTDFLLVAAPFYHIRGEEGRVYVYQVPEQDASFSLAHTLSGHPGLTNSRFGFAMAAVGDINQDKFTDVAIGAPLEGFGAGDGASYGSVYIYNGHSGGLYDSPSQQIRASSVASGLHYFGMSVSGGLDFNGDGLADITVGSRDSAVVLRSRPVVDLTVSMTFTPDALPMVFIG-------KMDVKLCFEVDSSGVASEPGLREMFLNFTVDVDVTKQRQRLQCEDSSGCQSCLRKWNGGSFLCEHFWLIS-TEELCEEDCFSNITIKVTYEFQTSGGRRDYPNPTLDHYKEPSAIFQLPYEKDCKNKVFCIAEIQLTTNISQQELVVGVTKEVTMNISLTNSGEDSYMTNMALNYPRNLQFKKIQKPVSPDVQCDDPKPVASVLVMNCKIGHPILKRSSVN-VSVTWQLEESVFPNRTADITVTISNSNEK-SLARETRSLQFRHAFIAVLS---RPSVMYMNTS-QSPSDHKEFFFNVHGENLFGAVFQLQICVPIKLQDFQIVRVKNLTKTQDHTECTQSQEPACGSDPVQHVKEWHSVVCAITSNKENVTVAAEISVGHTKQLLRDVSELPILGEISFNKSLYEGLNAENHRTKITVIFLKEEETRSLPLIIGSSIGGLLVLVVIIAILFKCGFFKRKYQQLNLESTRRAQLKADSLLQD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R6T8-1", "uniprot_id": "M0R6T8_RAT", "id": "M0R6T8-1", "name": "", "aln": "MKWFFHALLCVASLKPLGAFNVDVDWSWVTALQPGAPSVLNSLLHQDPSNNQTCLLVARRSSNRNSAVLYRCATSIIPDEIGCQPVEHILMPKGRYQGVTLVRNHNG-VLVCIQVQSRKPRSLNSELTGACSLLTPNLDLQAQAYFSDLEGVLDLGASVNSGDYYGSKGGSTGEETKSARRLRRQAVEEED---------EEEAGTEIAIVLDGSGSIEPSDFQKAKDFISTMMRNFYEKCFECNFALVQYGGVIQTEFDLLDSRDINASLAKVQSIVQVKEVTKTASAMQHVLDNIFIPSRGSRKKALKVMVVLTDGDIFRDPLNLTTVISSSKMQGVVRFAIGVGNAFENNNTYRELKLIASDPKAAHTFKVTNYSALDGLLSKLQQRIIHMEGTVGDTLQYQLAQTGFSAQILDKGQ---VLLGTVGAFNWSGGALLYNTQNGRGRFLNQTAKE--DFRAAQYSYLGYSVAALHKAHGVSYVAGAPRHKLRGAVFELQKEDGEE-TFMRRIEGEQMGSYFGSVLCPVDINMDGITDFLLVAAPFYHIRGEEGRVYVYRVHEQDAPFSLVYTLSGYPGLTSSRFGFAMAAVGDINQDKFTDVAIGAPLEGFGAGDGASYGSVYIYNGHSGGLHASPSQQIRASSVALGLYYFGMSVSGGLDFSGDDLADITVGSQDVAVVLRSRPVVDLTVSMTFTPDALPMAFKD-------KMDVELCFKVDSSAVPSEPGLRGMSLNFTVDVDVTKQKQRLQCADRSCCQSCLMKWSGGSSLCEHFGLISTEEELCEDDCFSNITIKVSYEFQTSEERRNHPNPILDHYKEPSAIFQLPYEKDCKNKVFCIAEIQLTTAISQQDLVVGITKEVTMNISLTNSGEDSYMTNMALNYPRNLQFKKIQKPLSPDIQCDDPKPVASVLVMNCKIGHPILKRSSVN-VSVTWQLEESIFPNRTADITVTISNSNEK-SLARETHSLQFRHAFIAVLS---RPSVMYMNTS-QSSSDHKEFFFNVHGENHFGAVFQLQICVPITLRDLQIIRVKHLTKTQAHTECTQSQEPTCGSDPVQNVEEWHSVICAITSNKENVTVAAEISMGHTKQLLRDISELQILGEISFNKSLYEGLNAENHRTKITVIFLKEEKPHSLPLIIGSSIGGLLVLVVIIAILFKCGFFKRKYKQLNLESVRKAQLKSDSLLED--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P38570-1", "uniprot_id": "ITAE_HUMAN", "id": "P38570-1", "name": "Integrin alpha-E", "aln": "-MWLFHTLLCIASLALLAAFNVDVARPWLTPKG-GAPFVLSSLLHQDPSTNQTWLLVTSPRTKRTPGPLHRCS--LVQDEILCHPVEHVPIPKGRHRGVTVVRSHHG-VLICIQVLVRRPHSLSSELTGTCSLLGPDLRPQAQANFFDLENLLDPDARVDTGDCYSNKEGGGEDDVNTARQRRALEKEEEEDKEEEEDEEEEEAGTEIAIILDGSGSIDPPDFQRAKDFISNMMRNFYEKCFECNFALVQYGGVIQTEFDLRDSQDVMASLARVQNITQVGSVTKTASAMQHVLDSIFTSSHGSRRKASKVMVVLTDGGIFEDPLNLTTVINSPKMQGVERFAIGVGEEFKSARTARELNLIASDPDETHAFKVTNYMALDGLLSKLRYNIISMEGTVGDALHYQLAQIGFSAQILDERQ---VLLGAVGAFDWSGGALLYDTRSRRGRFLNQTAAAAADAEAAQYSYLGYAVAVLHKTCSLSYIAGAPRYKHHGAVFELQKE-GREASFLPVLEGEQMGSYFGSELCPVDIDMDGSTDFLLVAAPFYHVHGEEGRVYVYRLSEQDGSFSLARILSGHPGFTNARFGFAMAAMGDLSQDKLTDVAIGAPLEGFGADDGASFGSVYIYNGHWDGLSASPSQRIRASTVAPGLQYFGMSMAGGFDISGDGLADITVGTLGQAVVFRSRPVVRLKVSMAFTPSALPIGFNG-------VVNVRLCFEISSVTTASESGLREALLNFTLDVDVGKQRRRLQCSDVRSCLGCLREWSSGSQLCEDLLLMPTEGELCEEDCFSNASVKVSYQLQTPEGQTDHPQPILDRYTEPFAIFQLPYEKACKNKLFCVAELQLATTVSQQELVVGLTKELTLNINLTNSGEDSYMTSMALNYPRNLQLKRMQKPPSPNIQCDDPQPVASVLIMNCRIGHPVLKRSSAH-VSVVWQLEENAFPNRTADITVTVTNSNERRSLANETHTLQFRHGFVAVLS---KPSIMYVNTG-QGLSHHKEFLFHVHGENLFGAEYQLQICVPTKLRGLQVVAVKKLTRTQASTVCTWSQERACAYSSVQHVEEWHSVSCVIASDKENVTVAAEISWDHSEELLKDVTELQILGEISFNKSLYEGLNAENHRTKITVVFLKDEKYHSLPIIIKGSVGGLLVLIVILVILFKCGFFKRKYQQLNLESIRKAQLKSENLLEEEN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RMI4-1", "uniprot_id": "A0A8M1RMI4_DANRE", "id": "A0A8M1RMI4-1", "name": "", "aln": "---MYRKLLFMMVLCNATGFNVQISP-------------LKHFTNEDPLFGQTIIQSK--DGIFVPSPIYGGLFECTLDNECSKVNISDENPKGMRQVASVASLTSQDQHVVMCNQVRTKIRGTEYLNGNCTLMSPSGKVKLSP--AELDNNMDNNNNNNNNNKYRGGRIDQVKWRKRREAQPNLGALEEEE------EEEEDPGTEIAFVLDGSGSIQYDDFEKAKDFIHTTMSNVWKTCFDCNFAIVQYGSSIRTELSLLDNEDGARSLQKVKQIKQIYNLTKTASAINHVLTDIFIPENGSKNNSEKIIIVLSDGKILGDPMTLDEVLNKTQMKGVTRYSIGVGDGILKNKDAIKEMTQIADP--GKYYSVSSYGALNDILSSLERGIIGTEGTQ-HGFKLQLAEAGFSSHLLYNEQKVEALFGAVGAYDWSGGVFLKSGN--TVKFLNDSHNET------KFGYLGYSVTSAHLPSKTLYISGAPRYNLTGAVFIFDGLEKYV------LHGDQVGSYFGSVLCALDINKDEHTDHLLVGAPHFHLNGEEGKVLVYKLNQEDRFERAPVELRGDAGQTFARFGAAIGSIGDIDNNKFNDVAVGAPLETG------SAGSVYIYSGFEEGLRFS--QKISPSDFGMKLVYFGQSVSVGPAPASD-IPCIAVGSLGRVSVFETIPVLIIEPTIKIDTEVIALTHQMNKISSELSMKITVCFNIKKGKLKAEK-SETQAVDYEIDLDSGASKKRLTCGADSLIKDTFTLTPDEECTNKKLTYLG------CFDCFSPIKIKLSFSLAS--NKNEAPIRILDAFTPTEVVKEIPFEKDCQAADCKPSITLSDSKISETTITMGETQNLNINFNFTNTGDPSYKTTLTLTYPSILSERKIEGAACP---------VKNDNQIQCHLQHPVFTRSAQTNLFISWQLNDKSDLKKSEIIANLTSQNNGIQLLDSRIYTFNVMYFLPILIRGSAEPNILRIEEGGKGKTQPIKFKIQFQGENKYGATIDVIITIKMDTSKTDLHITK--------------IQPEVCVLEANKVKEASYIYKCTLKELQIITIEANVFIHDVQDTS---EKIIVEGQYSYDETLYSAKDTIKS-FTLEVPVTKMQVMTSKGPIIGGSIGGFLFLLIFIIILIKCGFFRRRHKVDQTQNQD--------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: ** : * .**::: *. : ::** .** : .. :: *: .: *** : .::. : : * .. *.* *:*: *. : .. :*:. :* . :..: . . . : . **: **: *****::*******: **::**:** . * *.::.**:****:****. *:**:.* :..* ** :*:.* *: .:******::*** .** ...**:.:: *:::**:** *: **:.* *:...:*:** *::****: : . . : :** : :.*:.* **:.:**.*. *: *** . :: ***: ***:::* : * .*:*:***::****.:* . . ***:: ::.****::: * . *::****:: **** : :.*:*:****** **.:**: * **.***.**.:*:.****:* **:: ::* * * .* * :*** *:.::**:.::*:.***:***** * ******.*. ** * *:* .* .. * *** *:: * .* :. *:**: . . *:.: **: : :: : ...:.: . :.: :**::.. :* . ::: :*:* .::** * . : . . :.: : **** .:*:::.: : : : * ** :. . .: ::*:** *: : : :*: :.:* *:::.:*:.:**:*: ** *.::*.** *. :::: . .* * . ::*:: **::.**: : : ***::. ::: *: ::.* * . :::. : : :: .*.:: :: . :. :. :* ::.:*** :** :: * : :: .* : .::*:* : .: : :*: *:: . :: :: : *: *::::**.. :: : .: * . * : * ** .*:**:*.*:::: **:*****:*::: : :. ", "identical_positions": 302, "similar_positions": 388, "identity": "25.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-676", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9P2D3-1", "uniprot_id": "HTR5B_HUMAN", "id": "Q9P2D3-1", "name": "HEAT repeat-containing protein 5B", "aln": "MELAHSLLLNEEALAQITEAKRPVFIFEWLRFLDKVLVAANKTDVKEKQKKLVEQLTGLISSSPGPPTRKLLAKNLAALYSIGDTFTVFQTLDKCNDIIRNKDDTAAYLPTKLAAVACVGAFYEKMGRMLGSAFPETVNNLLKSLKSAESQGRSEILMSLQKVLSGLGGAAASSHRDIYKNARSLLTDRSMAVRCAVAKCLLELQNEAVFMWTAELENIATLCFKALENSNYGVRVAVSKLLGTVMATALMPKQATVMRQNVKRATFDEVLELMATGFLRGGSGFLKSGGEMLKVGGSVNREVRVGVTQAYVVFVTTLGGQWLERSFATFLSHVLDLVSHPRATQTHVEAVYSRRCVSFILRATVGSLLGEKAQIAAAKEICQAIGKQMKAVEAVVNDTSGENKSGAADIAASQHVMVCALQELGSLVQSLNATASPLIQEASIGLLEIVTSVLLHPSMAARLAAAWCLRCVAVALPFQLTPFLDRCAERLNNLKTSPEAVSGYSFAMAALLGGVHQCPLGIPHAKGKMVVSIAEDLLRTAAQNSRLSLQRTQAGWLLLGALMTLGPSVVRYHLPKMLLLWRNVFPRSLKELEAEKARGDSFTWQVTLEGRAGALCAMRSFVAHCPELLTEDVIRKLMTPIECAMTMMSHIPSVMKAHGAHLKASAAMVRLRLYDILALLPPKTYEGSFNALLRELVAEFTLTDNSANTTTSLLRSLCHYDDSVLLGSWLQETDHKSIEDQLQPNSASGSGALEHDPSSIYLRIPAGEAVPGPLPLGVSVIDASVALFGVVFPHVSYKHRLQMLDHFAECVKQAKGVRQQAVQLNIFTAVLSALKGLAENKSTLGPEEVRKSALTLVMGPLDNPNPILRCAAGEALGRMAQVVGEATFIARMAQYSFDKLKSARDVVSRTGHSLALGCLHRYVGGIGSGQHLKTSVSILLALAQDGTSPEVQTWSLHSLALIVDSSGPMYRGYVEPTLSLVLTLLLTVPPSHTEVHQCLGRCLGAIITTVGPELQGNGATTSTIRSSCLVGCAITQDHSDSLVQAAAISCLQQLHMFAPRHVNLSSLVPSLCVHLCSSHLLLRRAAVACLRQLAQREAAEVCEYAMSLAKNTGDKESSSANVSPFAPGVSSRTDIHCRHQGVNITETGLEGLLFGMLDRETDRKLCSDIHDTLGHMLSSLAVEKLSHWLMLCKDVLAASSDMSTATLLSSGK---DEEAEKKDEMDDDTMFTTLGEEDKSKPFVAPRWATRVFAADCLCRIINLCENADQAHFDLALARSAKLRNPTNDLLVLHLSDLIRMAFMAATDHSNQLRMAGLQALEDIIKKFASVPEPEFPGHVILEQYQANVGAALRPAFSQDTPSDIIAKACQVCSTWIGSGVVSDLNDLRRVHNLLVSSLDKVQAGKGSSSQLYRESATTMEKLAVLKAWAEVYVVAMNIKKEAESKPKRAIKNTDDDDDDCGTIDELPPDSLITLVQPELPTLSRLWLAALKDYALLTLPAEFSSQLPPDGGAFYTPETIDTARLHYRNSWAPILHAVALWLNSTGFTCSESTEAAAISGLQKRSTSVNLNQASGAVGSAKSLPEINKDRMHLILGVSIQFLCSPRPEEPIEHVTACLQALHTLLDSPYARVHIAEDQLIGVELLSVLHRLLLTWNPSSVQLLVTGVVQQIVRAAQDYLQEKRNTLNEDDMEKEACTVLGEGGDSGGLIPGKSLVFATMELLMFILVRHMPHLSTKVSDSPSHIATKTRLSEESARLVAATVTILSDLPSLCSPAGCMTILPTILFLIARILKDTAIKSADNQVPPPVSAALQGIKSIVTLSMAKTEAGVQKQWTALIRSTLACILEYSQPEDSVPTPDEVSMLTAIALFLWSASNEIIGVQSLQNGCMNRFKNALNSCDPWVQAKCYQLLLSVFQHSNRALSTPYIHSLAPIVVEKLKAVERNRPASNIELLAVQEGIKVLETLVALGEEQNRVQLLALLVPTLISYLLDENSFASASSASKDLHEFALQNLMHIGPLYPHAFKTVMGAAPELKVRLETAVRASQAS-KAKAAARQPAPAIHSAPTIKLKTSFF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C547-1", "uniprot_id": "HTR5B_MOUSE", "id": "Q8C547-1", "name": "HEAT repeat-containing protein 5B", "aln": "MELAHSLLLNEEALAQITEAKRPVFIFEWLRFLDKVLVAANKTDVKEKQKKLVEQLTGLISSSPGPPTRKLLAKNLAALYSIGDTYTVFQTLDKCNDIIRSKDDTAAYLPTKLAAVACVGAFYEKMGRMLGSAFPETVNNLLKSLKSAESQGRSEILMSLQKVLTGLGGAAASSHRDIYKNARSLLTDRSMAVRCAVAKCLLELQNEAVFMWTAELENVATLCFKALENSNYGVRVAVSKLLGTVMATALMPKQATVMRQNVKRATFDEVLELMATGFLRGGSGFLKSGGEMLKVGGSVNREVRVGVTQAYVVFVTTLGGQWLERSFATFLSHVLDLVSHPRATQTHVDAVYSRRCVSFMLRATVGSLLGEKAQIAAAKEICQAIGKQMKAVEAVVNDTSSENKSGTADIAASQHVMVCALQELGSLVQSLNATASPLIQEASIGLLEIVTSVLLHPSMAARLAAAWCLRCVAVALPFQLTPFLDRCAERLNNLKTSPEAVSGYSFAMAALLGGVHQCPLGIPHAKGKMVVSIAEDLLRTAAQNSRLSLQRTQAGWLLLGALMTLGPSVVRYHLPKMLLLWRNVFPRSLKELEAEKARGDSFTWQVTLEGRAGALCAMRSFVAHCPELLTEDAIRKLMTPIECAMTMMSHIPSVIKAHGAHLKASAAMVRLRLYDILALLPPKTYEGSFNALLRELVAEFTLTDNSANTTTSLLRSLCHYDDSVLLGSWLQETDHKSIEDQLQPNSASGSGALEHDPSSIYLRIPAGEAVPGPLPLGVSVIDASVALFGVVFPHVSYKHRLQMLDHFAECVKQAKGVRQQAVQLNIFTAVLSALKGLAENKSTLGPEEVRKSALTLVMGALDNPNPILRCAAGEALGRMAQVVGEASFIARMAQYSFDKLKSARDVVSRTGHSLALGCLHRYVGGIGSGQHLKTSVSILLALAQDGTSPEVQTWSLHSLALIVDSSGPMYRGYVEPTLSLVLTLLLTVPPSHTEVHQCLGRCLGAIITTVGPELQGNAATISTIRSSCLVGCAITQDHSDSLVQAAAISCLQQLHMFAPRHVNLSSLVPSLCVHLCSSHLLLRRAAVACLRQLAQREAAEVCEYAMSLAKNAGDKEISGGNVNPFTPGVSSRSDVHCRHQGVNITDTGLEGLLFGMLDRETDRKLCSDIHDTLGHMLSSLAVEKLSHWLMLCKDVLAASSDMSAATLLSSGK---DEESEKKDEMDDDAMFTTLGEEDKSKPFVAPRWATRVFAADCLCRIINLCENSDQAHFDLALARSAKLRNPKNDLLVLHLSDLIRMAFMAATDHSNQLRMAGLQALEDIIKKFASVPEPEFPGHVILEQYQANVGAALRPAFSQDTPSDIIAKACQVCSTWIGSGVVSDLNDLRRVHNLLVSSLDTVQAGKGSSSQLYRESATTMEKLAVLKAWAEVYVVAMNIKKEAESKPKRAMNNPDDDDDDYGTIDELPPDSLITLVQPELPTLSRLWLAALKDYALLTLPAEFSSQLPPDGGAFYTPETIDTARLHYRNSWAPILHAVALWLNSTGFISQESTEATTVSGVQKRSPAVSLNQVPGAMASAKPLPEVNKDRMHLILGVSIQFLCSPRPEEPIEHVTACLQALHTLLGSPYARIHIAEDQLIGVELLSVLHRLLLTWNPPSIQLLVTGVVQQIVRAAQDYLQEKRNALNEEDMEKESCPTLGEGGDTGGLIPGKSLVFATMELLMFILVRHMPHLSTKMLDSPSHTAMKTQLSEESARLVAATVAILSDLPSLCSPAGCMTILPTILFLIARILKDTAIKSADNQVPPPVSAALQGIKSIVTLSMAKTED-TQKQWTTLIRSTLACILEYSQPDDCMPAPDEVSTLTAIALFLWSASSEIIGVQSLQNGCMNRFKSALNSCDPWVQAKCYQLLLSVFQHSNRALSTPYIHSLAPLVVGKLKAVERHRPASSTELLAVQEGIKVLETLVALGEEQNRVQLLALLVPTLISYLLDENSFASASSISKDLHEFALQNLMHIGPLYPHAFKTVMGAAPELKARLETAVRASQAS-KAKAAARQPAPTTHSTPTIKLKTSFF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4ISV1-1", "uniprot_id": "A0A0R4ISV1_DANRE", "id": "A0A0R4ISV1-1", "name": "HEAT repeat-containing protein 5B", "aln": "MELAHSLLLNEEALSHITEAKRAVFIFEWLRFLDKVLIAANKVDVKEKQKKLVEQLTGLISSSPGPPTRKLLAKNLAVLYSIGDTFTVFQTLDKCNDIIKSKDDTAAYLPSKLAAVACVGAFYERMGRMLGSSFPETINNLLKALKSAEAQGRGEILLSLQKVLSGLGGAAASCHRDIYKNTRSMLSDRSMAVRCAVARCLLELQNEAVFIWTTELENVATLCFKALEGSTYDVRVAVSTLLGTVMATALMPKQATVMRQNVKRATLEEVLELMATGFLRGGSGFLKSGGEMLKG-ASVSREVRVGVTQAYVVFVTVLGGQWLERNFAVFLSHLLELVAHPRATQTHVEAVYSRRCVSFALRATLGGLLGEKAQIAAAKEICLAISKQMRAVEAVVNEQSSENRTGAADVSASQHVMVCALKELGRLVQSLSATASPLIQEPSIGLLETVLSVLLHPSMAARLAAAWCLRCVCVALPHQLTPLLERCADCINTLKNSPEAVSGYSFAMAALLGGVHQCPLGVPHSKGKMVVSIAEDLLRSAAQNSRLSLQRTQAGWLLLGALMTLGPSLVRYHLPKMLLLWRNVFPRSQKELEAEKARGDSFSWQVMLEGRAGALCAMRSFVAHCPELLTEDVIRRLMTPIECAMTMMSHIPAVIKVHGAHLKASAAMVRLRLYDILALLPPKTYEGSFNALLRELVAEFTLTDNSANTTTSLLRSLCHYDDSVLMGSWLQETDHKSIEDQLQPNSASGSGALEHDPSSIYLRVPAVEAVPGPLPLGVSVIDASVALFGVVFPHVSFKHRLQMLDHFAECIKQAKGVRQQAVQLNIFTAVLSALKGLAENKSSLGLEEVRKSALALVMGALDNSNPILRCAAGEALGRMAQVVGEASFIARMAQHSFDKLKSARDVVSRTGHSLALGCLHRYVGGIGSGQHLKTSVSILLALAQDATCHEVQTWALHSLALIVDSSGPMYRGYVEPTLSLVLTLLLTVPPSHTEVHQCLGRCLGALITTVGPELQGNSVSISTIRSSCLVGCAIMQDHSDSLVQAAAISCLQQLHMFAPRHVNLSSLVPSLCVHLCSSHLLLRRAAVACLRQMAQREAAEVCEYAMSLARRAGDTKDNS-------------------TTNLNITETGLEGVLFGMLDRETDRKLCSDIHDTLGHMLSSLAVEKLSHWLKLCKDVLAATTEVGGAVASDSRRKDDDEDSEKKDEMDDDIMFTSLGQDEKMKATVAPRWVTRVFAAECLCRIIHLCENADHAHFHLAEARIAKIKNPEADFLVLHLCDLIRMAFMAATDHSNQLRMAGLQALEDIIKKFAAVPDPEFPSHVILEQYQANVGAALRPAFSPDTPSDITAKACQVCSAWIGSGVVSDLNDLRRVHNLLVSSLDKVQTGKSSSSQLYSESATTMEKLAVLKAWAEVFVVAMDIKQESRARPVRPPAGEDEDEDE--AADVLPPDSLMVLVQPELPSLSRLWLELLRDYALLTLPAEFSSQLPADGGAFYTPETIDTARLHYRSSWASVLHAEALWLSSTGFGITEDSAAS-----------------GAAVQPAKHPEELVKDRLHLLLGISIEFLCFPRAEEPIEDVMSCLRAVCTLLDSPIARTHIAEDQLLAVELLNVLHRLLLTRDPSSVQLQVTAVVQKTIHAAQEHLEQRRS--NKGGVNEDGVCVLGEGADSGELLPGKSLVFAAMELLVFILVRHLPQLKEKNTDTCRRSPQS--LSEHSSRLVANSVTALAELPSLCSPAGSMTILPTVLFLITGVLRETAVKTADNSVSAPVSAALQAIKTILSSTAAHTHA----QWSALVRSSLATVLEDSQPSD---SVDEVSFLAAITLFLLSASGDLMSVCVLQKGCIERFTHALNSADPWTQARCCQLLLSILQQPSRSLSVPFIHTLAPLLVEQLKSVERRRVCNAAELQAVQERVRVMETLVNMAEEHNRVQLLALLVPTLVSYLLDDSSFSSSSSSSKGLHDFALQSLMHTGPLYPAAFMTVIGAAPELKTRLEAAIRSKQAHSRAKSTARQTLPAAPAAPTIKLKTSFF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************::******.**************:****.**********************************.*******:*************:.*********:*************:*******:****:*****:*****:***.***:******:********.*******:**:*:***********:***********:**:****:*********.*.*.******.**************************::************************** .**.****************.********.**.****:*:**:*********:********** ****:*.*************** **.***:*******: *.**::*:**::**********:*** *****.*********.****** * *********************.****.****:*:***: :*.**.*************************:**:**************:****************************:******************* *************:*** *************************.**:****************:*:*.********************************************************************:*************************************:** *****************************:*************:*******************************:** ********:****.***.**********************:*******:**************************************************.*. *****:**************************************************:***********..: ************* *********************************************************:****************:.:**.: .. .:***:*****:************************************* ********::::. *. .* : **::********* ***:**:::* *. *****.******:******:****:*:***.** ** **::** *:*****.*********************************:**:****.******************** ****** ********:*************************.**:**.****** ******************:****:**:*:.::* *. . *:*:*: : * ******:.*******:****** *:****************.*******************.***.:*** ****.**** *.: *: .*: .** *: ***:**:**:**:*** **.*****.* :**:*: ***.** ** *******:.****.******** :*.*:** **.***: ::***::*:::*. *: .::::. .****.*:* *:********:****:******:*:*. * *: : . . ***.*:**** :*: *::*********.******:****: :*::**:*:***.*..*******.**:*:: : *:*. **::*:**:** :** ***.* : **** *:**:*** ***.:::.* **:**::**. ****.***.**:* *****::*:..*:**.*:**:***::* :**:***.* .. ** **** ::*:**** :.**:*************:*****:.**:*:** **.**:****.*** ***** ** **:*******.***:*:*:.** :**::***. *: ::**********", "identical_positions": 1623, "similar_positions": 297, "identity": "78.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-683", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVM7-1", "uniprot_id": "DJC16_RAT", "id": "Q5FVM7-1", "name": "DnaJ homolog subfamily C member 16", "aln": "-MELKRLSISWQFLIVLVLILQSLSALDFDPYRVLGVSRTASQADIKKAYKKLAREWHPDKNKDPGAEDKFIQISKAYEILSNEEKRTNYDHYGDAGENQGYQ---QQREYRFRHFHENFYFDESFFHFPFNSER-RDSID-EKYLLHFSHYVNEVVPDSFKKPYLIKITSDWCFSCIHIEPIWKEVVQELEGLGVGIGVVHAGYERRLAHHLGAHSTPSILGIINGKISFFHN-AVVHENLRQFVESLLPGNLVEKVTNKNYVRFLSGWQQENKPHALLFGQTPAAPLLYKLTAFAYKDYVSFGYVYVGLRGVEEMTRQYNVNIYAPTMLIFKEHINKPADAIQARGLKKQVIEDFITQNKYLLASRLTSQKLFHELCPVKRSHRQRKYCVVLLTAEANKLSKPFDAFLSFALAN--TQDTVRFVHVYSSRQQEFASTLLPDIEAFQGKSGVSILERRNTAGRVVFKTLEDPWTGS------ESDKFVLLGYLDQLRKDPAFLSSEAVLPDLTDELAPVFLLRWLYSVSDYLSDFWESLLHSNWREMMPLLSLIFSALFILFGTVIVQAFSDSNEERESHPPDKEEVPEKAGKTEPSFTKESSSKIPKKGFVEVTELTDVTYTSNLVRLRPGHMNVVLILSNSTKTSLLQKFALEVYTFTGSSSLHFSFLTLDKHREWLEYLLEFAQDAAPIPNQYDKH-FMERDYTGYVLALNGHKKYFCLFKPLKTVD-EETVGSC-DLDS-----------------SRGKPPCGLGPKPLKGKLSKLSLWMERLLEGSLQRFYIPSWPELD------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TN4-1", "uniprot_id": "DJC16_MOUSE", "id": "Q80TN4-1", "name": "DnaJ homolog subfamily C member 16", "aln": "-MELKRLGVSWRFLMVLVLILQSLSALDFDPYRVLGVSRTASQADIKKAYKKLAREWHPDKNKDPGAEDRFIQISKAYEILSNEEKRTNYDHYGDAGENQGYQK--QQREHRFRHFHENFYFDESFFHFPFNAER-RDSGD-EKYLLHFSHYVNEVLPESFKRPYLIKITSDWCFSCIHIEPVWKEVVQELEGLGVGIGVVHAGYERRLAHHLGAHSTPSILGVISGKITFFHN-AVVHENLRQFVESLLPGNLVEKVTNKNYVRFLSGWQQENKPHALLFGQTPAVPLMYKLTAFAYKDYVSFGYVYVGLRGVEEMTRQYNVNLYTPTMLIFKEHINKPADVIQARGLKKQVIEDFIAQNKYLLASRLTSQRLFHELCPVKRSHRQRKYCVVLLTAETNKVSKPFEAFLSFALAN--TQDTVRFVHVYSNRQQEFASTLLPDMEAFQGKSGVSILERRNTAGRVVFKTLEDPWTGS------ESDKFVLLGYLDQLRKDPAFLSSEAVLPDLTDELAPVFFLRWLYSVSDYLSDFWESLLHSNWREMMPLLSLIFSALFILFGTVMVQAFSDSNEERESHPADKEEVPEKAGKTEPSFTKESSSKIPKKGFVEVTELTDVTYTSNLVRLRPGHMNVVLILSNSTKTSLLQKFALEVYTFTGSSSLHFSFLTLDKHREWLEYLLEFAQDAAPIPNQYDKH-FMERDYTGYVLALNGHKKYFCLFKPLKTVD-EETVASC-DPDS-----------------SRGKPSCGLGPKPLKGKLSKLSLWMERLLEGSLQRFYIPSWPELD------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2G8-1", "uniprot_id": "DJC16_HUMAN", "id": "Q9Y2G8-1", "name": "DnaJ homolog subfamily C member 16", "aln": "-MEVRKLSISWQFLIVLVLILQILSALDFDPYRVLGVSRTASQADIKKAYKKLAREWHPDKNKDPGAEDKFIQISKAYEILSNEEKRSNYDQYGDAGENQGYQKQQQQREYRFRHFHENFYFDESFFHFPFNSER-RDSID-EKYLLHFSHYVNEVVPDSFKKPYLIKITSDWCFSCIHIEPVWKEVIQELEELGVGIGVVHAGYERRLAHHLGAHSTPSILGIINGKISFFHN-AVVRENLRQFVESLLPGNLVEKVTNKNYVRFLSGWQQENKPHVLLFDQTPIVPLLYKLTAFAYKDYLSFGYVYVGLRGTEEMTRRYNINIYAPTLLVFKEHINRPADVIQARGMKKQIIDDFITRNKYLLAARLTSQKLFHELCPVKRSHRQRKYCVVLLTAETTKLSKPFEAFLSFALAN--TQDTVRFVHVYSNRQQEFADTLLPDSEAFQGKSAVSILERRNTAGRVVYKTLEDPWIGS------ESDKFILLGYLDQLRKDPALLSSEAVLPDLTDELAPVFLLRWFYSASDYISDCWDSIFHNNWREMMPLLSLIFSALFILFGTVIVQAFSDSNDERESSPPEKEEAQEKTGKTEPSFTKENSSKIPKKGFVEVTELTDVTYTSNLVRLRPGHMNVVLILSNSTKTSLLQKFALEVYTFTGSSCLHFSFLSLDKHREWLEYLLEFAQDAAPIPNQYDKH-FMERDYTGYVLALNGHKKYFCLFKPQKTVEEEEAIGSCSDVDSSLYLG-----------ESRGKPSCGLGSRPIKGKLSKLSLWMERLLEGSLQRFYIPSWPELD------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BDP4-1", "uniprot_id": "A0A8M2BDP4_DANRE", "id": "A0A8M2BDP4-1", "name": "DnaJ homolog subfamily C member 16", "aln": "-MRTVVGLLSVIMLYVLLNDATVESTAEFDPYKVLGVTRSASQAEIKKVYKRLAKEWHPDKNKNPEAEDMFIKITKSYEILTNEEKRASYDRYGQTDDTQPYG----HRHHGFRHFHDNFYFDESFFHFPFNNKGGRDFAD-SKYTLHFNQYVNEVVPDSFKRPYLIKITSDWCFSCIHIEPVWKETVQELETLGIGIGVVDVGYERRLANHLGAHQTPSILGVVNGKVSFFHY-AVVKEHLIQFVDDLLPQRLIEKVTDKNNHEFLKSWHELNKPHVLLFDQVPSVPLLYKLTAFAFKDYVQFGYVDQGLSETAELLRKFNINTYAPTMLVFKEDVEKPADIIQAKGMKKQIIDEFISNNKFLLAPRLVNQKLFDELCPVKQFHRRRKYCILLITGEDESYIPGNEAFLSLASAN--ANDVLRFAYVYHRRQQPLCDILLKDKDDT--APQVVILERRNGAGKILYKPLLGGWNGS------KEDKHKLLEELQRLQKDPSILNYNAILPELNNEFASMFLVRWIYTAYDYLSEIIDDLLHNNWREMMPLLSLIFSALFILFGTVVIQAFSDSSEEKQPKMKVKETKSENG---SPNTSNASSSRPPKKNFVEVTELTDITYTSNLVKLRPGHINVVLVLTDGTKNILLSKFAKEVYSFTGSLTLHFSFLNVDKHKEWMAAVLEFAQDAMQIDTDEDEMGTRKVDYTGYVLALNGHKKYLCLFKPVYTGEDLDGKAEEEGGVSR---------------SRKSTTRSRSTTLQIHHKLDRLGLWMERLMEGTLPRYYVPAWPGLDKITVNK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7PLG1-1", "uniprot_id": "Q7PLG1_DROME", "id": "Q7PLG1-1", "name": "DnaJ homolog subfamily C member 16", "aln": "MISCLISNYIITILVLCTTSYIHVCSSLNDPYAILGINKKATTYEIREAYKELAKKWHPDKVKNDYGAEKFIQIKLAYEILADLDRRRIFDRYGVSDINSQYF----QKKHDYSEYNR-FTLNQNDDDFGQRFDIKQDIAFYQKLSITENYFEKMILSKNAKKVHVVMFYNDWCFKCTRIVDAFKKILELLQPIGINFATVNAVHEESVFRKCGAREVPQLVLILDNQYFLYRDHSFTPQKVVEFIRKKIPFNVFKRIEHDNFNDFLGGWSD-NRARALIFEPRSLTRLRYLLTAFEFYDRVAFGFVNTISKDSSNIITRFKVNTSLDTLILFNEDTTTFTASVCMEEIPNHILVNMVSTNQFLAFPRISSQNIMESVCPTEWNRQRKHLCVILITENNRKKDFERVALRNIALSVGYNSEKVRFAYIFKESQPDFIKSISKGSFKDSLIEIVIIWRRDKKRIKYNWVYVAKQNGNSSPEHLMNSTKDQISNAVKKLLKNSEALCYEAIVENLFNEHSQGILTKWISQFLYVVDYLSDNIEDEHLLAVFSLLGTIAFMFTVGYVLIYFVRVEEKYLKAHGHLIDIQD----------------QRHINLIPELKLYELRAEKYNGMVRLLKPGCRTLLLINDCQSRHKLIPYFHKAVWPYRKSKTLLFGHMVIERGLPWFAEILRLSLSKNRHLQVNPRN------CVGTVLALNGHRKYFCMYHAKHPESALGTKRTLKNTQKLLDANEDPEIGTFLKRDFSEESESEPNILLEDNLLNGLDNWLERLFDGRTQKYYINYWPDFITK----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* : .: *** :**:.:.*: :*::.**.**::***** *: . : **:*. :****:: ::* :*:** :. .. * ::.: : .:: * :::. .* . . :* .* : . : : ::... *: ::: : .****.* :* :*: :: *: :*:.:..*.. :*. : .: **:..*.:: ::..: ::: :.. ::: :*: . :* .:.::: ..* ** .* : *:.:.*:* . . * * **** : * : **:* :: ::::* *:::*:*. : : . : :::: :::: *::* .*: .*.::..:**.: ::::: *::*:* : . *: .:* : .: :**.::: * : . : . * * .* : : : : .* :. * : :.:* *:. * :*:: :* :* : :: :*: :. :.: ..: ::.**. * : : : : . ..:. : . : . : ::: ** .*.. : *:** .::*: :: *: * *:.: * * *..: ::: *: :*.:: . . .* *******:**:*:::. . . . . . . . *. *. *:***::* ::*: ** : ", "identical_positions": 137, "similar_positions": 295, "identity": "16.87%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-684", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O75064-1", "uniprot_id": "DEN4B_HUMAN", "id": "O75064-1", "name": "DENN domain-containing protein 4B", "aln": "MAEERPPRLVDYFVVAGLAGNGAPIPEETWVPEPSGPLRPPRPAEPITDVAVIARALGEEVPQGYTCIQASAGGHPLELSAGLLGGTQPVICYRRGRDKPPLVELGVLYEGKERPKPGFQVLDTTPYSHSANLAPPGPGHPRTYLTYRRAAEGAGLHALGITDLCLVLPSKGEGTPHTYCRLPRNLNPGMWGPAVYLCYKVGLAKANTLVYEAELLGRYPEEDNEAFPLPESVPVFCLPMGATIECWPAQTKYPVPVFSTFVLTGAAGDKVYGAALQFYEAFPRARLSERQARALGLLSAVERGRALGGRAVRSRRAIAVLSRWPAFPAFRAFLTFLYRYSVSGPHRLPLEAHISHFIHNVPFPSPQRPRILVQMSPYDNLLLCQPVSSPLPLSGASFLQLLQSLGPELAITLLLAVLTEHKLLVHSLRPDLLTSVCEALVSMIFPLHWQCPYIPLCPLVLADVLSAPVPFIVGIHSSYFDLHDPPADVICVDLDTNTLFQTEEKKLLSPRTLPRRPYKVLLATLTNLYQQLDQTYTGPEEEASLEFLLTDYEAVCGRRARLEREVQGAFLRFMACLLKGYRVFLRPLTQAPSEGARDVDNLFFLQGFLKSRERSSHKLYSQLLHTQMFSQFIEECSFGSARHAALEFFDSCVEKVHPEQEKPEPTPLVELEELSGSELTVFITPPEEPALPEGSESTPQYCYDGFPELRAELFESLQEQPGALPVPGPSRSAPSSPAPRRTKQEMKVAQRMAQKSAAVPELWARCLLGHCYGLWFLCLPAYVRSAPSRVQALHTAYHVLRQMESGKVVLPDEVCYRVLMQLCSHYGQPVLSVRVMLEMRQAGIVPNTITYGYYNKAVLESKWPSGTPGGRLRWAKLRNVVLGAAQFRQPLRERQQQQQQQQQQQQQQQQEQVSAHQEAGSSQAEPYLERPSPTRPLQRQTTWAGRSLRDPASPPGRLVKSGSLGSARGAQPTVEAGVAHMIEALGVLEPRGSPVPWHDGSLSDLSLTGEEPLPGGSPGGSGSALSAQSTEALEGLSGRGPKAGGRQDEAGTPRRGLGARLQQLLTPSRHSPASRIPP----------PELPPDLPPPARRSPMDSLLHPRERPGSTASESSASLGSEWDLSESSLSNLSLRRSSERLSDTPGSFQSPSLEILLSSCSLCRACDSLVYDEEIMAGWAPDDSNLNTTCPFCACPFVPLLSVQTLDSRPSVPSPK-SAGASGSKDAPVPGGPGPVLSDRRLCLALDEPQLCNGHMGGASRRVESG------AWAYLSPLVLRKELESLVENEGSEVLALPELPSAHPIIFWNLLWYFQRLRLPSILPGLVLASCDGPSHSQAPSPWLTPDPASVQVRLLWDVLTPDPNSCPPLYVLWRVHSQIPQRVVWPGPVPASLSLALLESVLRHVGLNEVHKAVGLLLETLGPPPTGLHLQRGIYREILFLTMAALGKDHVDIVAFDKKYKSAFNKLASSMGKEELRHRRAQMPTPKAIDCRKCFGAPPEC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A987-1", "uniprot_id": "A0AB13A987_DANRE", "id": "A0AB13A987-1", "name": "", "aln": "MTEERCPQLVDYFVVAGLTGASAPLDEE-------GQQRGVRAVLPVTDLAVIARGLGEDVPEGFTCIEKTPGGHPAELSAGLLNNTHMFLCYRRGHDKPAIVELGVLYEGKDSVRPGWQVIETTPYSRSASLSSSGPTTHRTFLMFRRAPDSQALNTLGVTEISLLMPSKGETAPHTYCRVDKNINTGMWGPALYLCYKRSAAKANALVYEAGLISRYPEQDLESFALPDSVPVFCLPMGVTVESWPLNTKYQLPVFSTFVLTSACGDKVYGAAIQFYEAYPRECVSERQCVRLGLLSVVDR-RPITNRSLQVKKSICVLSHWPFFSVFQKFLTFIYRYSISGPHVLPLEKHISSFMHNVPFPSAQRPRILVQLSPYDNLLLCQPVSSPLPLSGASFVKLLQNLGPENTCSLLLAVLTEHKLLLHSLRPDVLTSVSEALLSMTFPLRWHCPYIPLCPLRMADVLCAPMPFIVGVHSSYFDLYDPPSDVVCVDLDTNTIFQSEDKKPLSWRSLPRKHGKILLNSLTNLHKTLEKIYTPGQEEATLEFLLTDYDLIYGRQKQLELEIQEAFLRFMSCLLRGYRSYLLPITQAPSDRTTDCSSLFNLQGFLKSRDRTQQKFYTQLTKTQMFTQFIEECSFVSDRHASLEFFDECVQKVDVE--KPEDVRLIEHDECVSGEHTVFIMPPEEPQQPDGSECPAQYSYDTFPVLQPDLFERPQDQ---LRTPARG-SAPNSPAPRRTKQEIKLAQKKAQKYSSVPEMWSKCLLGHCYGLWFICLPTFVRAESGKVRALHTAYEVLKHMETRKVVLPDEVCYRILMQLCGQYGQPVLAVRVLLEMKRAGITPNTITYGYYNKAVLESKWPSTNQGGRLRWAKLRNVLLAVAQFRQPIK---QQQRSASFSIPSDVLNKPRPHSALIRQSSWSGLSESSSHESLTSLAKSNSLSSVQPTGSKLTLKKAGDVSADAGSRKPPAGRRDTLSPPAPVLVRRS------DVCLSTFYRDCAEPADADCRTQP-AERDSRSVEVKETLNRKSVDEN--YNTVSSPSRGLAGKLQQLLTPTRNRASVRRAASVDDRRANGNARRAHEQKPSRKSQMAESLLKAKERLYNATSESSLSVGSDIDMADMQTLAIPLRKSWDSAQEAGG------IEVLMSSCSLCRSCNSLVYDEEIMAGWSSDDSNLNSTCPFCSAPFVPLLNAEICDPGPVCSTERGTLHAEDELENAMRPPAGRDDTLQHLCNGSREADSSSETSSQSESSVPSGGGAPQVTVEYLSPLVLRKEMESLLENEGEGVLSQVLLLDSHSIIFWNLVWYFTRLGLPTNLPQLLRASPLTAAFTQG------LEGVSVRVRLLWDTLSPDTEQWPPLYMLWRIHSGALVRSYSWKHHNHPFSLSFLEELLRWIGMNEVHKAITHFLETLAKQNTQPRIQRSLYREMLFLTLAAMGKDHV--ASFDKRYKAAYVRLCSSVGREELKKKRVQPPSAKAIDCRRCFLLPLHC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*** *:**********:* .**: ** * * *.. *:**:*****.***:**:*:***: :.**** *******..*: .:*****:***.:**********: :**:**::*****:**.*:..** **:* :***.:. .*::**:*::.*::***** :******: :*:*.******:***** . ****:***** *:.****:* *:*.**:**********.*:*.** :*** :*********.*.********:*****:** :****. *****.*:* *.: .*::: :::*.***:** *..*: ****:****:**** **** *** *:*******.********:***********************::***.**** : :************:******:****.***:** ***:*:********* :****.**:*****:*******:***:**:********:**:*:** ** *:***: *:** :****:: *:: ** :***:********: : **: :** *:* ******:***:*** :* *:*****: : * ..** ********:*:.:*:*:** :****:******** * ***:*****.**:**. * *** . *:* :* ..* **** ***** *:***...**.** ** *:.:*** *:* * .*. . ***.**********:*:**: *** ::***:*::***********:***::**: ..:*:******.**::**: ***********:*****.:******:***:***::***.******************** . ************:*..******:: ***:. . . .: :: .*. ..: . *...*. ..* :. . * :*:.. * *:*.:.: *:: . . : . ** *. * .** : ** ... . : .::*.*. * *. :. . . : ..:* ***..:*******:*: .: * .. .. . : *. : . :***:.:** .::**** *:**: *::: . :.**:* : .:: * :*:*:*******:*:************:.******:*****:.******..: *. * .: : : *... : .: .* : ::** . *.: .. . :. * ** : **********:***:****. **: * .:*.******:*** ** **: ** *: ** .:.:*. : .**:******.*:**.:. ****:***:** * .:**::**.:** :*:******: :****. * ::**.:***:****:**:***** .:***:**:*: :*.**:*:***:::*.* *:.******:** * .*", "identical_positions": 816, "similar_positions": 395, "identity": "53.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-685", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZDU2-1", "uniprot_id": "D3ZDU2_RAT", "id": "D3ZDU2-1", "name": "Regulatory-associated protein of mTOR", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MEVLERLLPRTPPPPPPLMESEMLQSPLMGLGEED----EADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSVALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMG-PQKALETIGANLQKQYENWQPRARYKQSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIYDLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINP-----------------NHPLAQMPLP---PSMKNCIQLAACEAHELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVS---------------LVPGVTLDLIEKIP-----GRLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSYNCTPVSSPRLPP-TYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSP------------------------------------------------------------------------------FFAEQLTAFQVWLTMGVENRSPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLLQSSARELRPLLVFIWAKILAVDSS-CQADLVKDNGHKYFLSVLADPY-----------------------------------------------------------MPAEHRTMTAFILAVIVNSYTTGQEACLQGNLI-AICLEQLSDPHPLLRQWVAICLGRIWQNFDSARWCGVRDSAHEKLYSLLSDPIPEVRCAAVFALGTFVGNSAERT-DHSTTIDHNVAM-MLAQLINDGSPMVRKELVVALSHLVVQYESNFCTVALQFMEE--------EKNYPLPSPA-ATEGGSLTPVRDSPCTPRLRSVSSYGNIRAVTTARNLNKSLQNLSLTEESGSSVAFSPGNLSTSSSASSTLGSPENEEYILSFETIDKMRRVSSYSALNSLIGVSFNSVYTQIWRVLLHLAADPYPDVSDLAMKVLNSIAYKATVNARPQRILDTSSLTQSAPASPTNKGMHIHQVG-------------GSPPASSTSS-CSLTNDVAKQTVSRDLPSSRPGTAGPTGAQYTPHSHQFPRTRKMFDKGPDQTTDDADDAAGHKSFICATMQTGFCDWSARYFAQP-------VMKIPEEH------DLESQIRKEREWRFLRNTRVRKQAQQVIQKGIT--RLDDQIFLNRNPGVPSVVKFHPFTPCIAVAD-KDSICFWDWEKGEKLDY-------------------------FHNGNPR------------------YTRVTAMEYLNGQDCSLLLTATDDGAIRVWKN--------FADLEKNPEMVTAWQGLSDMLPTTR--------------------------GAGMVVDWEQETG-LLMSSGDVRIVRIWDTDRETKVQDIPTG-ADSCVTSLS---CDSHRSLIVAGLGDGSIRVYDRRMALSECRVMTYREHT----AWVVKAYLQKHPEGHIVSVSVNGDVRFFDPRMPES-VNVMQIVKG-----------LTALDIHPQANLIACGSMNQFTAIYNGNGELINNIKYYDG-----------------FMGQRVGAISCLAFHPHWPHLAVG-SNDYYISVYSVEKRVR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K4Q0-1", "uniprot_id": "RPTOR_MOUSE", "id": "Q8K4Q0-1", "name": "Regulatory-associated protein of mTOR", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MESEMLQSPLMGLGEED----EADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSVALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMG-PQKALETIGANLQKQYENWQPRARYKQSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIYDLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINP-----------------NHPLAQMPLP---PSMKNCIQLAACEAHELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVS---------------LVPGVTLDLIEKIP-----GRLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSYNCTPVSSPRLPP-TYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSP------------------------------------------------------------------------------FFAEQLTAFQVWLTMGVENRSPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLLQSSARELRPLLVFIWAKILAVDSS-CQADLVKDNGHKYFLSVLADPY-----------------------------------------------------------MPAEHRTMTAFILAVIVNSYTTGQEACLQGNLI-AICLEQLSDPHPLLRQWVAICLGRIWQNFDSARWCGVRDSAHEKLYSLLSDPIPEVRCAAVFALGTFVGNSAERT-DHSTTIDHNVAM-MLAQLINDGSPMVRKELVVALSHLVVQYESNFCTVALQFMEE--------EKNYPLPSPA-ATEGGSLTPVRDSPCTPRLRSVSSYGNIRAVTTARNLNKSLQNLSLTEESGSSVAFSPGNLSTSSSASSTLGSPENEEYILSFETIDKMRRVSSYSALNSLIGVSFNSVYTQIWRVLLHLAADPYPDVSDLAMKVLNSIAYKATVNARPQRILDTSSLTQSAPASPTNKGMHMHQVG-------------GSPPASSTSS-CSLTNDVAKQTVSRDLPSSRPGTAGPTGAQYTPHSHQFPRTRKMFDKGPDQTTDDADDAAGHKSFICASMQTGFCDWSARYFAQA-------VMKIPEEH------DLESQIRKEREWRFLRNTRVRKQAQQVIQKGIT--RLDDQIFLNRNPGVPSVVKFHPFTPCIAVAD-KDSICFWDWEKGEKLDY-------------------------FHNGNPR------------------YTRVTAMEYLNGQDCSLLLTATDDGAIRVWKN--------FADLEKNPEMVTAWQGLSDMLPTTR--------------------------GAGMVVDWEQETG-LLMSSGDVRIVRIWDTDRETKVQDIPTG-ADSCVTSLS---CDSHRSLIVAGLGDGSIRVYDRRMALSECRVMTYREHT----AWVVKAYLQKHPEGHIVSVSVNGDVRFFDPRMPES-VNVMQIVKG-----------LTALDIHPQANLIACGSMNQFTAIYNGNGELINNIKYYDG-----------------FMGQRVGAISCLAFHPHWPHLAVG-SNDYYISVYSVEKRVR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N122-1", "uniprot_id": "RPTOR_HUMAN", "id": "Q8N122-1", "name": "Regulatory-associated protein of mTOR", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------MESEMLQSPLLGLGEED----EADLTDWNLPLAFMKKRHCEKIEGSKSLAQSWRMKDRMKTVSVALVLCLNVGVDPPDVVKTTPCARLECWIDPLSMG-PQKALETIGANLQKQYENWQPRARYKQSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEVWVFNKNYTQYIPLSIYDLQTWMGSPSIFVYDCSNAGLIVKSFKQFALQREQELEVAAINP-----------------NHPLAQMPLP---PSMKNCIQLAACEATELLPMIPDLPADLFTSCLTTPIKIALRWFCMQKCVS---------------LVPGVTLDLIEKIP-----GRLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSYNCTPVSSPRLPP-TYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSP------------------------------------------------------------------------------FFAEQLTAFQVWLTMGVENRNPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLLQSSARELRPLLVFIWAKILAVDSS-CQADLVKDNGHKYFLSVLADPY-----------------------------------------------------------MPAEHRTMTAFILAVIVNSYHTGQEACLQGNLI-AICLEQLNDPHPLLRQWVAICLGRIWQNFDSARWCGVRDSAHEKLYSLLSDPIPEVRCAAVFALGTFVGNSAERT-DHSTTIDHNVAM-MLAQLVSDGSPMVRKELVVALSHLVVQYESNFCTVALQFIEE--------EKNYALPSPA-TTEGGSLTPVRDSPCTPRLRSVSSYGNIRAVATARSLNKSLQNLSLTEESGGAVAFSPGNLSTSSSASSTLGSPENEEHILSFETIDKMRRASSYSSLNSLIGVSFNSVYTQIWRVLLHLAADPYPEVSDVAMKVLNSIAYKATVNARPQRVLDTSSLTQSAPASPTNKGVHIHQAG-------------GSPPASSTSS-SSLTNDVAKQPVSRDLPSGRPGTTGPAGAQYTPHSHQFPRTRKMFDKGPEQTADDADDAAGHKSFISATVQTGFCDWSARYFAQP-------VMKIPEEH------DLESQIRKEREWRFLRNSRVRRQAQQVIQKGIT--RLDDQIFLNRNPGVPSVVKFHPFTPCIAVAD-KDSICFWDWEKGEKLDY-------------------------FHNGNPR------------------YTRVTAMEYLNGQDCSLLLTATDDGAIRVWKN--------FADLEKNPEMVTAWQGLSDMLPTTR--------------------------GAGMVVDWEQETG-LLMSSGDVRIVRIWDTDREMKVQDIPTG-ADSCVTSLS---CDSHRSLIVAGLGDGSIRVYDRRMALSECRVMTYREHT----AWVVKASLQKRPDGHIVSVSVNGDVRIFDPRMPES-VNVLQIVKG-----------LTALDIHPQADLIACGSVNQFTAIYNSSGELINNIKYYDG-----------------FMGQRVGAISCLAFHPHWPHLAVG-SNDYYISVYSVEKRVR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IFI0-1", "uniprot_id": "A0A0R4IFI0_DANRE", "id": "A0A0R4IFI0-1", "name": "Regulatory-associated protein of mTOR", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MKMDAELLHSPVLGLAEEE----EVDMTDWNLPLAFMKKRHTEKIEGYKALAQSWRMKDRMKTVSVALVLCLNVGVDPPDVVKTSPCARLECWIDPLSMS-PQKALETIGANLQKQYENWQPRARYKQSLDPTVDEVKKLCTSLRRNAKEERVLFHYNGHGVPRPTVNGEIWVFNKNYTQYIPLSVYDLQTWMGSPSIFVYDCSNAGIIVKSFKQFALQREQELEVAAINP-----------------NHPLAQMPLP---PSMKNCIQLAACDASELLPMNPDLPADLFTSCLTTPIKIALRWFCMQKSAK---------------LVPGVTLDLIEKIP-----GRLNDRRTPLGELNWIFTAITDTIAWNVLPRDLFQKLFRQDLLVASLFRNFLLAERIMRSYNCTPVSSPRLPP-TYMHAMWQAWDLAVDICLSQLPTIIEEGTAFRHSP------------------------------------------------------------------------------FFAEQLTAFQVWLSMGVENRNPPEQLPIVLQVLLSQVHRLRALDLLGRFLDLGPWAVSLALSVGIFPYVLKLLQSSARELRPLLVFIWAKILAVDSS-CQADLVKDNGHKYFLSVLADPF-----------------------------------------------------------MPAEHRTMAVFILAVIVNNYNTGQEACLQGNLI-AICLEQLNDPHPLLRQWVAICLGRIWQNYDSARWCGVRDSAHEKLYSLLSDSIPEVRCAAVFALGTFVGNSAERT-DHSTTIDHNVAM-MLAQLINDGSPIVRKELVVALSHLVVQYESNFCTVALQFMEE--------EKNYAVPSPANSTETGNITPSRDSPAIPRLRSVNSYTNLRAATTARTLNKSLQNLNLNEE-GGPAAFSPGNLSTSSSASSTLGSPDNDEYLLSFETIDKMRRVSSYSSLNSLIGVSFNSVYTQIWRVLLHLAADPFPDVSDLAMKVLNSIAYKATMNARTQRILDSGSLTQSAPASPTSKGTLIHQAGASHRSKCSSSPSSGSPPMPGASS-SSLTNEVPKPPV-RDGPSARPPYT-PTLGGQAPHSQQFPRTRKMFDKGPDQTAEDGDETAVHRSFVSLSLQTGLCDWSAKYFAQP-------VMKIPEEH------DSESQVRKDREWRFLRNARVRKQSQRITQRGVT--RLDDQIFINRNPGVPSVVKFHPFNPCIAVAD-KDSICFWDWEKGERLDY-------------------------FYNGNPR------------------YTRITAMEYLNGHDCSLLLTATDDGALRIWKN--------FADQ-RNPEMVTAWQGLSDMLPTTRGLARRVS----------IYLDRSKQGGAGMVVDWEQETG-LLMTSGDVRVIRIWDTEREIKVQDIPTG-ADSCVTSLS---CDPQRSLVAAGLGDGSVRVYDRRMGPNECRVMTYREHG----AWVVKAHLQKEPEGHIISVSVNGDVRFFDPRMPES-VNTLQTVKG-----------LTALDIHPQANLFACGSMNQFIAVHNSNGDVISNIKYYDG-----------------FMGQRIGAISCLAFHPFWPHLAVG-SNDYYMSIYSAEKRLR---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W437-1", "uniprot_id": "Q9W437_DROME", "id": "Q9W437-1", "name": "", "aln": "MTSAVRAKSAAAAVGVAVDESSGSSNGSVADQEVASSKEAVLSVLIRKRYEKYVFAPWDDPIILIMEQLEHIEHCRSAALGNQVAIGRDPSQDDSLNDLGKVISNMRQDQSLVPIVKHIEQISDIQASNGQELASLGSLRELIRTIRKEWPRDDSIKLRLKEIQILGMPPARSLCFGERIRDDRCPLSLQTKRHKERIQAMMYERQPWRIRERMKTASVALVLCLNIGVDPPDVVKIQPCSRLECWIDPSSVS-PPKAMELIGSNLQMQYERWQPRARYKKCNDPTVDDVKKLCTSLRRNAKGERILFHYNGHGVPKPTANGEIWVFNKTFTQYIPLSIFELITWMSAPSIYVYDCSNAGIIINSFQPYAKQHEEELGKALAAAQQRGGVQQLVGGSGGAANVAANQVQLTNQMVSYKNCIHLAACAANEILPMNAQLPADLFTSCLTTPINIALKWYAMQEKLG---------------MVPRIQSELIDKIP-----GKVNDRRTMMGELNWIFTAITDTIAWNTLPRELFQRLFRQDLLVASLFRNFLLAERILRSHDCTPVSLPALPP-CYRHPMWKAWDLVVDLALQQLPEILDHNAPYRQLP------------------------------------------------------------------------------FFEHQLTAFQVWLDSESESRTPPEQLPIVLQVLLSQVHRLRALELLARFLDLGPWAVNLALGVGIFPYVLKLLQSSTRELRPVLVFIWAKILAVDPS-CQVDLVKEY--KYFLSVLQDTS-----------------------------------------------------------VSKEHRTLSAFVLSSIVHNFLLGQTSALQGPLL-SICLEQLNDGSWLLRQWLAICLGMLWQNFEKARWSGARDLAHEKLYVLLRDSIPEVRAAAVFALGTFISSVTDRSEEQANNIDRIIAITMLETVGEDMSPLVRMELAAALQWMVVLFESQFVAVYLTEHMRGHV-----SAASFVMCPDPRDLTSSTHSLERHVTIRRGASSSSISNMGGASISSGTGSSSNPLGRSKS-GSGSSGGRGAAGAAGGTNSIPFQSIFTKLWLGICNLAQDPFPRVAAIAQEIVEHVRDTALCPIMAAKEATMANASEKCSSLSVSLPPSPNTRVNYLGGGGAPGGAGATAESPPVGAAASGASHWAQKLR---------LSGSGACMGAGDPQTILQRKLRTSSINDETDSGPGYSRGVAGAGT--GLGLPSGPRESTHSARSSGSESNHYLEPGHSLTPIVLTEFIPWAISYFTRPGKERYSSAEGSAEEGRQRFPVDRNSAELRRRRLRFLRNDFVRRHAGRKHQELIDPYGFDVCVWNRKTQFTPSIVKLLPYEPQIAVAY-REKVLVYDFQYNSVRTYGAESLGGNFTGYSSGYGSGSGSSSSLNGSTPRKSGAHTSGGGGGGFSAAPFARVSSIEFINAQDMALNLVAHEDGVVRVWQSSPPASSATSEDTPSKARLVTAWTALGQVNQHNHRQRSVASGGSIGKGADASGLSSAAIGSGGIVTAWQQCSQHLVIGGGGCRFIRIWDVERELKLADIPLGRSETCARVLSPYLPNMRSDVILAGCDDGSVRLFDKRCAPQDAGISVYRRHS----APILHASLRAN-GLVLVSGCTEGRISVADMRGSQSSINPFDVVYEWDAGGD-----VTAITSHQLEDTVACGNASK-IVIYSLDGRQQKVLRTNEG-----------------FIGPKIGHPTYLYFHPYKAQLAVG-FVDNTVAIYSPTPVL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38873-1", "uniprot_id": "KOG1_YEAST", "id": "P38873-1", "name": "Target of rapamycin complex 1 subunit KOG1", "aln": "------------------------------------------------------------------------------------------------------------------------------MPEIYGPQPLKPLNTVMRHGFEEQYQSDQLLQSLANDFIFYFDDKR--------HKTNGNPIPEEDKQRDVNRYYQPITDWKIMKDRQKTVSAALLLCLNLGVDPPDVMKTHPCARVEAWVDPLNFQDSKKAIEQIGKNLQAQYETLSLRTRYKQSLDPCVEDVKRFCNSLRRTSKEDRILFHYNGHGVPKPTKSGEIWVFNRGYTQYIPVSLYDLQTWLGAPCIFVYDCNSAENILINFQKFVQKRIKDDEEG---------------------NHDVAAPSPT---SAYQDCFQLASCTSDELLLMSPELPADLFSCCLTCPIEISIRIFLMQSPLKDSKYKIFFENSTSNQPFGDSKNSFKSKIPNVNIPGMLSDRRTPLGELNWIFTAITDTIAWTSLPRPLFKKLFRHDLMIAALFRNFLLAKRIMPWYNCHPVSDPELPDSITTHPMWKSWDLAMDEVLTKIVIDLKNAPPATALESQMILQQQETLQNGGSSKSNAQDTKAGSIQTQSRFAVANLSTMSLVNNPALQSRKSISLQSSQQQLQQQQQQQQQFTGFFEQNLTAFELWLKYASNVRHPPEQLPIVLQVLLSQVHRIRALVLLSRFLDLGPWAVYLSLSIGIFPYVLKLLQSPAPELKPILVFIWARIMSIDYKNTQSELIKEKGYMYFVTVLVPDWGVNGMSATNGSAMINSGNPLTMTASQNINGPSSRYYERQQGNRTSNLGHNNLPFYHSNDTTDEQKAMAVFVLASFVRNFPLGQKNCFSLELVNKLCFYIDNSEIPLLRQWCVILLGLLFADNPLNRFVCMNTGAVEILLKSLKDPVPEVRTASIFALKHFISGFQDAEVILRLQQEFEEQYQQLHSQLQHLQNQSHLQQQQSQQQQQHLEQQQMKIEKQIRHCQVMQNQLEVIDLRKLKRQEIGNLISILPLINDGSSLVRKELVVYFSHIVSRYSNFFIVVVFNDLLEEIKLLEKSDIN---TRNTSDKYSVSQGSIFYTVWKSLLILAEDPFLENKELSKQVIDYILLELSAHKELGGPFAVMEKFLLKRSSKAHQTGKFGFNSSQVQFVKSSLRSFSPNERVDNNAFKKEQQQHDPKIS-------------------HPMRTSLAKLFQSLGFSESNSDSDTQSSNTSMKSHTSKKGPSGLYLLNGNNNIYPTAETPRFRKHTEPLQLPLNSSFLDYSREYFQEP-------QMKKQEAD------EPGSVEYNARLWRRNRNETIIQETQGEKKLSIYG-NWSKKLISLNNKSQPKLMKFAQFEDQLITADDRSTITVFDWEKGKTLSK-------------------------FSNGTPFG------------------TKVTDLKLINEDDSALLLTGSSDGVIKIYRD---------YQDVDTFKIVSAWRGLTDMLLTPR--------------------------STGLLTEWLQIRG-SLLTTGDVKVIRVWDAHTETVEVDIPAK-TSSLITSLT--ADQLAGNIFVAGFADGSLRVYDRRLDPRDSMIRRWRAGNDKQGVWINNVHLQRGGYRELVSGATNGVVELWDIRSEDPVESFVDQNVTSQYGSQQKPTTMTCMQVHEHAPIIATG--TKQIKIWTTSGDLLNSFKNSHNNGVTSTLAATGIPKSLSYSSTSDAFLSSMAFHPHRMMIAATNSHDSIVNIYKCEDERIDYF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . :: : . . .:: : . : :::* **.*.**:****:*******:* **:*:*.*:** .. . **:* ** *** *** . *:***:. ** *::**::*.****.:* :*:**********:** .**:****: :*****:*:::* **:.:*.*:****..* *: .*: :. :: :: . * . : ::*::**:* : *:* * .:******:.*** **:*::: : **. . .: .*** * :.**** :****************. *** **::***:**::*:********:**: ::* *** * ** *.**::***.:* * :: :.. .. ** .:****::** : * ******************:*** **.********** *:*.:************.: **:*:******:*:::* . * :*:*: **::** . *:::::.*:*: :*..: ** .:. *: :*: .. ***** .* ** :: : *: . * * * * *.:**** *::*** *:.. : : * .. . : : : . :.:: . : . . * :: . : * . . :.. * . .: : : :.:: : . . . . : : : .. . : : : . : . . :. . : : : : : :: ** .. * : * . * * ** : :.: : : . : .. *.::*: : : .* :..: .:*:: .. : ...* :::: :: :* .* :* *.. .**.:::::. : . .:*:** .* :: : . *::. * * :: *. :.:*:**.. * *** :.: *: : .:. ** ***:*::*:* :. : :* . : :. *: ::* ..:* : . * * :. . .: :*.: * .* * .: : . .* . :: .. : . . : : ***. :*. * : :*. ", "identical_positions": 339, "similar_positions": 373, "identity": "18.47%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-689", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P16284-1", "uniprot_id": "PECA1_HUMAN", "id": "P16284-1", "name": "Platelet endothelial cell adhesion molecule", "aln": "MQPRWAQGATMWLGVLLTLLLCSSLEGQENSFTINSVDMKSLPDWTVQNGKNLTLQCFADVSTTSHVKPQHQMLFYKDDVLFYNISSMKSTESYFIPEVRIYDSGTYKCTVIVNNKEKTTAEYQVLVEGVPSPRVTLDKKEAIQGGIVRVNCSVPEEKAPIHFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKSELVTVTESFSTPKFHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKDKAIVAHNRHGNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAP------PANFTIQKEDTIVSQTQDFTKIASKSDSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTKNSNDPAVFKDN----PTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSKVVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKILTVRVILAPWKKGLIAVVIIGVIIALLIIAAKCYFLR-----KAKAKQMPVEMSRP--AVPLLNSNNEKMSDPNMEANS--HYGHNDDVRNHAMKPINDNKEPLNSDVQYTEVQVSSAESHKDLGKKDTETVYSEVRKAVPDAVES-------RYSRTEGSLDGT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q08481-1", "uniprot_id": "PECA1_MOUSE", "id": "Q08481-1", "name": "Platelet endothelial cell adhesion molecule", "aln": "----------MLLALGLTLVLYASLQAEENSFTINSIHMESLPSWEVMNGQQLTLECLVDISTTSKSRSQHRVLFYKDDAMVYNVTSREHTESYVIPQARVFHSGKYKCTVMLNNKEKTTIEYEVKVHGVSKPKVTLDKKEVTEGGVVTVNCSLQEEKPPIFFKIEKLEVGTKFVKRRIDKTS-NENFVLMEFPIEAQDHVLVFRCQAGILSGFKLQESEPIRSEYVTVQESFSTPKFEIKPPGMIIEGDQLHIRCIVQVTHLVQEFTEIIIQKDKAIVATSKQSSEAVYSVMAMVEYSGHYTCKVESNRISKASSIMVNITELFPKPKLEFSSSRLDQGELLDLSCSVSGTP------VANFTIQKEETVLSQYQNFSKIAEESDSGEYSCTAGIGKVVKRSGLVPIQVCEMLSKPSIFHDAKSEIIKGHAIGISCQSENGTAPITYHLMKAKSDFQTLEVTSNDPATFTDK----PTRDMEYQCRADNCHSHPAVFSEILRVRVIAPVDEVVISILSSNEVQSGSEMVLRCSVKEGTSPITFQFYKEKEDRPFHQAVVNDTQAFWHNKQASKKQEGQYYCTASNRASSMRTSPRSSTLAVRVFLAPWKKGLIAVVVIGVVIATLIVAAKCYFLR-----KAKAKQKPVEMSRP--AAPLLNSNSEKISEPSVEANS--HYGYDDVSGNDAVKPINQNKDPQNMDVEYTEVEVSSLEPHQALGTRATETVYSEIRKVDPNLMEN-------RYSRTEGSLNGT---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B6F6-1", "uniprot_id": "A0ACD6B6F6_DANRE", "id": "A0ACD6B6F6-1", "name": "Platelet endothelial cell adhesion molecule", "aln": "-----MRAGLLWLGLAG---LWQALG-TRAAITIDQVRLTVHPGNEVVSGTNLILRCEADVSHSLSRPPTHSFSFLHNGQVVYSKNISASVVERTFSPARVSNSGQYECTVRIEDKAKTSNRQTLRITGLQTPTMKVKSDIVSEGEDIIATCSAAEETGTLMFLFYEDNQ-------EVKSEVSNTNTISITLTMKKLTDIYLHCAYMVVRHPTAGFSNNSNTVKVFVRDLKELIPQISFSPSASVVEGERVAIKCEVQD----RSALEMFLTKDGTILQR--FHTSFTYSLTVREEDSGDYVCKTEKGSVQKKVENRLSVTALFTRPILTMSPYEVFEGEFFKLNCSSSVISNKISKEDIKYVLLKDGQRISTNPIFRKSASLVNNGKYSCWAMARGVNKTSLPHLLKAKVPVSVP--VLSAVGKVIVGRPFKVLCEAKNGTLPITYTLLKDHTPVDSRVVNGTERAIFTITSIRFPGEIDSFTCQAYNGP-RFIRTSDALTAPVIVPVSEPMLKPQETTVTE-GSDLVLICSVQEGSYPITFTWYHDKLLLLYSRQEVQSSKGSHVVKMITRDQRGDYHCEASNQALETKQ---SKPARIGVSLALWKKALIGVLCILLLVAIVVVLTVFFKKTSHPRRKRQATELSVKPSRPKSGDPMRMSLTLDIEDNTVLNGTPCVMGRNVWSENASGSDSDDHTDEESELVQPEQADPSREIPMPKNAEDEYIIQHTEVQVSTPGVPEQAEGQAALEYVQLNNSEQETHDT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.: * :* . ::**:.: : *. * .* :* *.* .*:* : . * . * ::. :.*. . . . :. .*: .** *:*** :::* **: . : : *: .* :.:... . :* : ..** **. .: * : : : . .. : * : : :.:: : . . : .:. : .. . *:: :.*.. ::** :: *:* :* :. *::: ** :*: .. .**: . * **.*.**.*.. :.* . :.:* **.:* * * .: :** :.*.** . . ::.: *: :* * * *. :.* * * * * * * : . :* * .* ::* *:.: : *:: .** **:* *:* . .:. ...: * *. . * . .: * * * : *: * . **.**.* :. .:. .: *.::** *:*:**: ***: :*::* : : : ::. : ::.*.*:*:* * *:* *. : * ** ***.**.*: * :::* ::: : : * :*.: .*: *** . *: * . .:.: .: .: * : * : . :::.: . *: :.: * . . ::*:: *. *. .* : :.* : * ", "identical_positions": 154, "similar_positions": 255, "identity": "20.08%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-691", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WV48-1", "uniprot_id": "SHAN1_RAT", "id": "Q9WV48-1", "name": "SH3 and multiple ankyrin repeat domains protein 1", "aln": "--MTHSPATSEDEER----------HSASECPEGGSESDSS-----------------------PDGPGRGP---QGTRGRGSGAPGNLAS---------------------------------------TRGLQGRSMS-VPDDAHFSMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGLFQPATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTE-GSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLYNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGANKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKYAARRRGPP-GAGLTVPPALLRANSDTSMALPDWMVFS-APGASSSGTPGPTSGPQGQSQPSAPSTKLSSGTLRSASSPRGARARSPSRGRHP--EDAKRQPRGRPSSSGTPRDGPAGGTGGSGGPGGSLGSRGRRRKLYSAVPGRSFMAVKSYQAQGEGEISLSKGEKIKVLSIGEGGFWEGQVKGRVGWFPSDCLEEVANRSQEGRQESRSDKAKRLFRHYTVGSYDSFDAPSLIDGIDSGSDYIIKEKTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDEAVHKKASQQAKRLPPPAISLRSKSMTSELEEMVSPWKK-------------------------------KIEYEQQPAAVPS-----------MEKKRTVYQMALNKLDEILAAAQQTISASESPGPGGLASLGKHRPKGFFATESSFDPHHRSQPS------YDRPSFLPPG--PGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPAPSSSGRLTPSPRGGPFNPSSGGPLPASSPSSFDGPSPPDTRGGGREKSLYHSAALPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTSGAPSPSHHSSSGGSSGPTQAPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGS-IPSASSPTSPALPRSEPPPAGPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPD---GAGGGGSSPSPAPATSPVPPSPSPVPTPASPSGP-----ATLDFTSQFGAALVGAARREGGWQNEARRR-STLFLSTDAGDEDGGDSG-------LGPGGPPGPRLRHSKSIDEGMFSAEPYLRLE-------------SGGSSGGYGAYAAGSRAYGGSG--SSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKE------------------SSEGGG---TPQP------PPRPPSPRYDAPPPTLHHHSPHSPHSPHARHEPVLRLWG----DPARRELGYRAGLGSQEKALTASPPAARRSLLHRLPPTAPGVGPLLLQLGPEPPTPHPGVSKAWRTAAPEEPERLPLHVRFLENCQARPPPAGTRGSSTEDGPG----------------VPPPSPRRVLPTSPTS-PRGNEENGLPLLVLPPPAPSVDVDDGEFLFAEPLPPPLEFSNSFEK--------------PESPLTPGPPHPLPDPPSPATPLPAAPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGAPAAP------------------GDPPAP--GPPAP--------------------------AAPAPPAPQPGP----------------------------------------------------------------------DPPP-----------GTDSGIEEVDSRSSSDHPLETISSAS---TLSSLSAEGGGNTGGVAGGG----AGVASGTELLDTYVAYLDGQAFGGS----GTPGPPYPPQLMTPSKLRGRALGTSGNLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALSACPGPSTAGVAGGPVAVEPEVPPVPLPAASSLPRKLLPWEEGPGPPPPPLPGPLSQPQ--ASALATVKASIISELSSKLQQFGGSSTAGGALPWARGGSGGSTDSHHGGASYIPERTSSLQRQRLSEDSQTSLLSKPSSSIFQNWPKPPLPPLPTGSGVSSSTAAAPGATSPSASSASASTR----HLQGVEFEMRPP-----------LLRRAPSPSLLPASDHKVSPAPRPSSLPILPSGPIYPGLFDIRSSPTGGAGGSTDPFAPVFVPPHPGISGGLGGALSG-----ASRSLSPTRLLS--------------------LPP---DKPFGAKPLGFWTKFDVADWLEWLGLSEHRAQFLDHEIDGSHLPALTKEDYVDLGVTRVGHRMNIDRALKFFLER----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YZU1-1", "uniprot_id": "SHAN1_MOUSE", "id": "D3YZU1-1", "name": "SH3 and multiple ankyrin repeat domains protein 1", "aln": "--MTHSPATSEDEER----------HSASECPEGGSESDSS-----------------------PDGPGRGP---QGTRGRGSGAPGNLAS---------------------------------------TRGLQGRSMS-VPDDAHFSMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGLFQPATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTE-GSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLYNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGANKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKYAARRRGPP-GAGLTVPPALLRANSDTSMALPDWMVFS-APGASSSGTPGPTSGSQGQSQPSAPSTKLSSGTLRSASSPRGARARSPSRGRHP--EDAKRQPRGRPSSSGTPRDGPAGGTGGSGGPGGSLGSRGRRRKLYSAVPGRSFMAVKSYQAQGEGEISLSKGEKIKVLSIGEGGFWEGQVKGRVGWFPSDCLEEVANRSQEGRQESRSDKAKRLFRHYTVGSYDSFDAPSLIDGIDSGSDYIIKEKTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDEAVHKKASQQAKRLPPPAISLRSKSMTSELEEMVSPWKK-------------------------------KIEYEQQPAAVPS-----------MEKKRTVYQMALNKLDEILAAAQQTISASESPGPGGLASLGKHRPKGFFATESSFDPHHRSQPS------YDRPSFLPPG--PGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPAPSSSGRLTPSPRGGPFNPGSGGPLPASSPSSFDGPSPPDPRSGGREKSLYHSGALPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTSGAPSPSHHSSSGGSSGPAQAPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGS-LPPASSPTSPALPRSEPPPAGPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPD---GAGGGGSSPSPAPATSPVPPSPSPVPTPASPSGP-----ATLDFTSQFGAALVGAARREGGWQNEARRR-STLFLSTDAGDEDGGDSG-------LGPGAPPGPRLRHSKSIDEGMFSAEPYLRLE-------------SGGSSGGYGAYAAGSRAYGGSG--SSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKE------------------SSEGGV---TPQP------PPRPPSPRYDAPPPTLHHHSPHSPHSPHARHEPVLRLWG----DPARRELGYRAGLGSQEKALTASPPAARRSLLHRLPPTAPGVGPLLLQLGPEPPTPHPGVSKAWRTAAPEEPERLPLHVRFLENCQARPPPAGTRGSSTEDGPG----------------VPPPSPRRVLPTSPTS-PRGNEENGLPLLVLPPPAPSVDVDDGEFLFAEPLPPPLEFSNSFEK--------------PESPLTPGPPHPLPDPPSPATPLPAAPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGAPAAP------------------GDPPAP--GPPAP--------------------------AAPAPPAPQPGP----------------------------------------------------------------------DPPP-----------GTDSGIEEVDSRSSSDHPLETISSAS---TLSSLSAEGGGNTGGVAGGG----AGVASGTELLDTYVAYLDGQAFGGS----GTPGPPYPPQLMTPSKLRGRALGTSGNLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALSACSGPSTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLSQPQ--ASALATVKASIISELSSKLQQFGGASTAGGALPWARGGSGGSTDSHHGGASYIPERTSSLQRQRLSEDSQTSLLSKPSSSIFQNWPKPPLPPLPTGSGVSSSTAAAPGATSPSASSASASTR----HLQGVEFEMRPP-----------LLRRAPSPSLLPASDHKVSPAPRPSSLPILPSGPLYPGLFDIRSSPTGGAGGSADPFAPVFVPPHPGISGGLGGALSG-----ASRSLSPTRLLS--------------------LPP---DKPFGAKPLGFWTKFDVADWLEWLGLSEHRAQFLDHEIDGSHLPALTKEDYVDLGVTRVGHRMNIDRALKFFLER----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y566-1", "uniprot_id": "SHAN1_HUMAN", "id": "Q9Y566-1", "name": "SH3 and multiple ankyrin repeat domains protein 1", "aln": "--MTHSPATSEDEER----------HSASECPEGGSESDSS-----------------------PDGPGRGP---RGTRGQGSGAPGSLAS---------------------------------------VRGLQGRSMS-VPDDAHFSMMVFRIGIPDLHQTKCLRFNPDATIWTAKQQVLCALSESLQDVLNYGLFQPATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQTE-GSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTPLFHTAMVGGDPRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQNASGNTALHICALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELIRNHREQDVVPFQESPKYAARRRGPP-GTGLTVPPALLRANSDTSMALPDWMVFS-APGAASSGAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHP--EDAKRQPRGRPSSSGTPREGPAGGTGGSGGPGGSLGSRGRRRKLYSAVPGRSFMAVKSYQAQAEGEISLSKGEKIKVLSIGEGGFWEGQVKGRVGWFPSDCLEEVANRSQESKQESRSDKAKRLFRHYTVGSYDSFDAPSLMDGIGPGSDYIIKEKTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNTLMVKVVMVTRHPDMDEAVHKKAPQQAKRLPPPTISLRSKSMTSELEEM---------------------------------------EYEQQPAPVPS-----------MEKKRTVYQMALNKLDEILAAAQQTISASESPGPGGLASLGKHRPKGFFATESSFDPHHRAQPS------YERPSFLPPG--PGLMLRQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGP-----ATLDFTSQFGAALVGAARREGGWQNEARRR-STLFLSTDAGDEDGGDGG-------LGTGAAPGPRLRHSKSIDEGMFSAEPYLRLE-------------SAGSGAGYGGYGAGSRAYGGGG--GSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKE------------------SSEGGG---APQP------PPRPPSPRYEAPPPTPHHHS------PHAHHEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPG----------------VPPPSPRRSVPPSPTS-PRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEK--------------PESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAP------------------GDPHPP--GPPAP--------------------------AAPAPAAPQPGP----------------------------------------------------------------------DPPP-----------GTDSGIEEVDSRSSSDHPLETISSAS---TLSSLSAEGGGSAGGGGGAG----AGVASGPELLDTYVAYLDGQAFGGS----STPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLAQPQ--ASALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTR----HLQGVEFEMRPP-----------LLRRAPSPSLLPASEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPTGGAGGSADPFAPVFVPPHPGISGGLGGALSG-----ASRSLSPTRLLS--------------------LPP---DKPFGAKPLGFWTKFDVADWLEWLGLAEHRAQFLDHEIDGSHLPALTKEDYVDLGVTRVGHRMNIDRALKFFLER----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TJV6-1", "uniprot_id": "A0AB32TJV6_DANRE", "id": "A0AB32TJV6-1", "name": "SH3 and multiple ankyrin repeat domains protein 1", "aln": "MTMPLSPLSSDEEQQRMLGNSQHLYPGAEEEEEEEEEMDDDGMDEEGEEENGELEMDDEEEVDDEDDIRRGPGHLRGGREEGHRQKGTMAGRLPGDRPIRPGNPGHAANPYSSNPGPTHQTSTNQQQQQPQRKLRERSSSNAPDDTHVALMVFRIGIPDIKQTKCLRFNPDATVWKAKQQVMCSLTESLRDVLNYGLFQPATDGHDAKFLEEERPLREYPQSFEKGVPYLEFRYKTRVYKQTNLDEKQLAKLHTKASLKKFMDYIQTSAVEKVAKLIDKGLDPNYHDPDTGETPLTLAVQTEPGGSEIIRVLVMGGAHIDFRARDGLTPLHKAVRAHAHTALLTLLSLGASSDYKDSRGLTPLYHTVLIGGDTSCCETLLYHRARLGLRDENGWDETHQACQNGNSQHLEHLLFYGADSSSQNASGNTALHICALYNKESCARILLYRGAKKDTKNNSGQNSFQVAVMSGHFELGEIIKNHRESDVVPFLESPKYAPQRRESSRTLGLPHPHPFLRANSDNSMNVPDWIAFPNAAGSSIVSVQGLKHG----------------GTLRSSSSPRGARTRSPSRGRTGDRDDRSRQTRGRQGAGSISSQGTAS---------------GQRRRLYSAVPGRVFVATRSHSAQGDREISFNKGDKVKVLSVGEGGYWEGTVRGRTGWFPSDCVEEVALRSLESRSESRSERAKRLFRHYTVGSYDSFDAP---------SDYIIKEKTVLLQKKDNEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMIRQGGNSLMVKVVMVTRNPDMEEGVRKKIPQQSKRLSTPAIALRSKSMTSELEEMEVPHCHYQHPHYRTQGLFLVTCLTNLSCNLPNFSVCPGIPYTVDRASAPWKKKSEFESSQATEKKRTVYQMALNKLDEILAAAQQTINTNEAPGPR-VQGVKRERGRGFYN-EPNFDQTGMGMTSSGAGLGYDRGQFVSGHGPPHGMLRQKSIGVPEEEKQFLHPPAMKFARSLSVPGPDEIPPPPTTAPPEPPFSSAPPLGFRGKTSQQPSVSMSQSTSSAAHYQLYSQSVHVTHGPRDRS---------PGPPTGSGTGDLAYSHAQAHPSVPSRTASRKVIGYTGDLAGAGG-----VAGAKAAALRRGYSNAVPPTSVATVIPQQQQTTQNQPSRMD--------RSGMGVGAGGVPKGGARRGKGPLVKQSKVEDLRQGQDTLEAKVS----------------VEKSSIPIPTIIVKAPSTSSSGRSSQGSSVEAEPPPPGE---SDSSKPEPVVPPPAPTVPPPAPPSIPAPPPPSLPSLRTQESLDFTSQFGAAIVGAARRDRERFHEARRKSASFFLSAEEELSGAGGAGGRTQTSQQQLSSQPSPRLRPSKSIDEGMFSGDTFIHHTRSMPPAFGLPEYSSPAPQGDYQPKSVPADFYGAGSRQQQQQQQQQAPTTTFIHPLTGKVLDPSSPLGLALAARERALKDDGRIRRERTTEHHFTRQLSSIGAFSSSTSQPTSHISYPMASSSSATSSAAQSTNTSSYLVTSSSLAATTTSTRPPSPRILRGAGSSWSEEAGVGERADREAAGTSAPREGLRVRFSEDKT-VHTHHYQSQQYQPTFKERERERQRERS-REREREREREREIEKAQTQYQQQSSQPMTQQPRRPSFLRMESEAGAYILSLTPPSPPPTAAPMRPTAGATGESGSGTSLMVLPPPAPSVDADD-EFVFADPLPPPLEFANSFDRGLGYSAMISHNVAARQQRHPPPPPPPPPPPTSKDSFMTGFPAHTPLPSPQAGDSTTSSLTSYDSEVANLTQSAPSPSPSSPNPLPPHSPSTLQTSGPPPPPSVSPPPPPNSYHRPFGLSQSQHLYNSTHTTGRSSSPTPPLSIPAPPAYRGPPTASSTPATSVSIRGASTVTASCSTTASTTVTSPSTTAAATPHTRIATVSTVATGGSRRPSAEHHPPPSATKSGESQETVVDSGIEELDSRSSSDHHLDSILALSGSGVRERLERAGMSSIGGIGGRDGATEVDRTSGADFLESYMSYLDGQTFEMHNAKAASTASTYPKTQRYREGTRAGDLRRQTSTAPPAYHRRREEEEEEDEAEEVEEEDLSARDGYGMREGPGIARSS-VMYFDRPRTPEIKPLWGDGSTGASQTMGEGGGQ----IVGTYVEPRKLHPPMTGMKANIINELSTKLQQRSKGTENWGAQRSLSRHR--FSEDSTGALSPPSVRSSSPSPVQLSQPALSPSPTPSSQPLYSNWARSPSPQPPAASSQPPPRSHSPVSPSSYSPYPTSPKHRPVYRTKALEFQFIPSRESRKSESHHAQRRRAPSPLISPSDRPKLGP-PRPSSLPILPTTPLYSSLYDLRGSITPPS--PANPLGDPYFSPSPPLFAPSGAPPPPNSSLVVSRSLSPTHFLSGTSSPPLHPIPPPTCLSYPHLPPPSPTKPFASKPLPYWTKYDVADWLGYLNLGEHRERFLDNEIDGTHLPSLTKDDYLDLGVTRVGHRMNIERALRRVMDRLSSSTFPISALSPRNGRTNRRRDEANRS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9K8-1", "uniprot_id": "A1Z9K8_DROME", "id": "A1Z9K8-1", "name": "", "aln": "-------------------------MSGSGAFDDE----------------------------------------------------------------------------------------------------------PPPEPRDGWLLVRIHVPELNVYKCLQFPSERLVWDVKQQVLASLPKELKESFNYGLFAPPANGKAGKFLDEERRLGDYP--FNGPVGYLELKYKRRVYKMLTLDERQLKALHTRANLRRFLECINGGHVEKIAKMCAKGLDPNFHCSESGDTPLTVATGAK-KPNKLLIALVNGGALLDYRTKDGSTALHRAVEHDSLEAVSTLLELGASPNYRDGRGITPLYISITRKCEAKITESLLHDHATLGIQDSQGWNEVHQACRHGLVQHLEHLLFYGADMDGRNASGNSPLHVCAVNNQEACARMLLFRGAQRGAQNFANQTPYQVAVIAGNLELAEIIENYKSEDIVPFRGPPRYNPKRRSGI-----------------------GWLSANGAAGAALLAAAGGGFG----------------GAMVGSNGAANGNNGAGGVGLMLSHQNHQQHHAGHHQQQHMHHQ--------------------HHQNHHQQLQQQQLPHLHTLQLHGP-PSPCPSEHMLGAYSSASSSLSEGSSGHRS---HEDDISIVTDKSLGDTSDIISDSSG-------VGTNSDSAACS-----------IGHPSTTVVCMEPYAGNTVGHIRLQPGDVIEVVGSTDCGLLEGYVRGTNQSG------------FFPADCVQEVSLRQKHITNVMTASTG------MAPQQQQQQHLQQAPAGSSAASYQGSPQLSLGGHSGS-----------------------------------------------------------------------------SSTLLQQPHQSPSLSVASNGSCQQPLESNEGGASGNGINNRNNNHSVGQYSSAT-------------------APRIKKSAYNAPRSVVLHRAKRGFGFILRGAKASSQLMQLRPSERFPALQYLDDVDPGGVADMAGLRPGDFLLTINGEDVTSASHEQVVEMIRS-------------AGALVNLTVVSPQFPHQMQASAQYLPSGAR-AGSHHLNSGPSTPQSSHRQCATLPRKMTGPGGSGPGSSSGGSVRMAPMPPRRDPKTTLSVG------RARAKSMVAGLENGGEKEDDLPHTKSNSVESIATPTP-----------------------TGIQTGPGTPVQLRTASIKARPTSSRITAAELEELFQRQQGEGSAANASRYATMMTSSRFQSGTDSGAATPPASNG-----SPMRSGPLVYGSVAEMKRKTARSKHGSGTLRGKPVATPTVGPGGAGGGR------------------------DLKRFHSTPDLHGP-------------------QLHGSASSIWQASGKGHHSQDDVATLHASLQRLNSNQGELKLGGLGAGSATGAGGAVLPP-------------------------------------PNHPPPPPPVGQVVKVETRSSVSEYESTISLQQKLKKRTENDAVTSAAIDGVQSSFNPSANAKIYASPQELRNVMAWKLRQAQEKPSQETSAGSQQPVSQYAAPTQMRPAQQQQQAQQPPTALASHYAAPQVQVQQVQQVQQSPQQS----------------APQSPPAPPLPQAAPVPAQNGNGNGSTSGAGSAPPIPEPDYSCSESDGEDENSILVARNTKLN--------------EKIALFDVPETSGNSQASGSSSNSGSASISHSLSVEEIQRIRSNLKTSKSSPNGFAKKPEEEK-----------------------------------------------------------PQQEQQQSHQ----------------------------------------------------------------------QPQQ-----------LLQPGEDECDNSSSGVSSEQEQLALA-----AGVTLPGGGKPTDTIKKK--------PSVTIVEEPKTIPDQPSSNTS-----HTTKPMAKTTISIGGG-GSAVPTATLTVKQLVQQQHAPVIQQQQQQLGSKQPVTAASTNKFTQQSNINSNVMSPQVLGRIPSHHHQQQSSNPNQKLIATQQQILQQQQQQLAHQQHLQQILKAKAAAAGGASNTAVLVAKHQQKLHKGTSSGHESEMETRSDLEDDDGDLSPSPPAKAFQRHNSLTRKQAAAIAMQRGATRTTAVSLMQLPPPLEADSDGEPSQLTLQRQQSHHPSQTHPHP----HQLQQQLQLQQQ-------------QQQQQQQQQPMAAHIVGMLPSGQLVAVASGAVAGVPGVGATAVQQGNNNLQQLCTDNLVLAPPPQFCDCNDAKHAP------QPHLPTSQYHP------------------------------QQQQQQQHQQQQQQQQQLQQQLQQQQMLQMHQRLSG----GAGAGAVGTLGRVRIVGAMPKANHHRLH-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... : * :.: . ::.** :*::: ***:* .: :* .****:.:*.:.*:: :***** *.:.*: .:**:*** * :** *: * ***::** **** .***:** ***::.*::*:: :: . :*:*:: ******:* .::*:****:*. :: ::: .* *** :*:*::** *.**:*. *: :**.**.*.:*:* **:***: : :. * **..:* **: *.:**:* ****:.* ***********: ..:*****:.**:**: *:*:***:**:***.:..:* .*..:****::*::**.*:*.*::..*:*** .*:* .:** .*: *.*:: .. * * *:: .:... ... : . * :: .:: *: : :::. :. : : : :: . :. . . . : . * .... ** * .* :. *: :* . .: *: : **: .. * * : .*.:: : * . :. ** . .* . *:...::.* :: .: : *.: ::::.*:: . . : :: : . .. :. .* ::* .:* : : . *:: :.. :: :. : . .*: : ... . .: :::.: ..... . .: * : ...: : *: * : . . : . . .. .. . ... . * .. :: : . : . : ... .:. .. . . . . . : . : . * .*...**. .: * ..: :::.* .: **: ::.* * : . .. . . : : ... . .:....* .: . . .::. *: : : .. . :. ..*.. * * . . :: . .. . .. .. ::. *: . * * .* .* * .... . . . * . : : . .:... . ... ..: . . *. : * .: : . . .: : . .* ..* * .. . . .* . . ..*. . . . : . * *: . : * . .: : . .. : : : *.*.: .*. ::: . * . .* :.* :* *. **. : : : : * .. . .. ::: : * : . . . . : : . . . . ... . : . . : . : .. . :: .: :. * * . .: *: :. . . * . . . : .. . : . : :::: :: . * :. * . :.: . . . ..* * : .. . . *..:: . : : : : * ::: :.:.:.* . ** .*: * . : ", "identical_positions": 253, "similar_positions": 596, "identity": "9.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-693", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C050-1", "uniprot_id": "KS6A5_MOUSE", "id": "Q8C050-1", "name": "Ribosomal protein S6 kinase alpha-5", "aln": "MEGEGGGSGGAG-TSGDSGDGGEQLLTVKHELRTANLTGHAEKVGIENFELLKVLGTGAYGKVFLVRKISGHDAGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSTVAKDLLQRLLMKDPKKRLGCGPRDAEEIKEHLFFEKIKWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYSPAALPQSSERLFQGYSFVAPSILFKRNAAVIDPLQFHMGVDRPGVTNVARSAMMKDSPFYQHYDLDLKDKPLGEGSFSICRKCVHKKTNQAFAVKIISKRMEANTQKEITALKLCEGHPNIVKLHEVFHDQVAASAQPPGQVVLCSLLLLALLFNRSLTRKPVTWTWLVHSTSQLPPLPPPMPEIVLFILLSDNGQLHTFLVMELLNGGELFERIKRKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLLFTDENDNLEIKVIDFGFARLKPPDNQPLKTPCFTLHYAAPELLTHNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHTCVKATFHAFNKYKREGFCLQNVDKAPLAKRRKMKRTSTSTETRSSSSESSRSSSSQSHG-KTTPTK---------------TLQPSNPTEGSNPDTLFQFSD---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75582-1", "uniprot_id": "KS6A5_HUMAN", "id": "O75582-1", "name": "Ribosomal protein S6 kinase alpha-5", "aln": "MEEEGGSSGGAAGTSADGGDGGEQLLTVKHELRTANLTGHAEKVGIENFELLKVLGTGAYGKVFLVRKISGHDTGKLYAMKVLKKATIVQKAKTTEHTRTERQVLEHIRQSPFLVTLHYAFQTETKLHLILDYINGGELFTHLSQRERFTEHEVQIYVGEIVLALEHLHKLGIIYRDIKLENILLDSNGHVVLTDFGLSKEFVADETERAYSFCGTIEYMAPDIVRGGDSGHDKAVDWWSLGVLMYELLTGASPFTVDGEKNSQAEISRRILKSEPPYPQEMSALAKDLIQRLLMKDPKKRLGCGPRDADEIKEHLFFQKINWDDLAAKKVPAPFKPVIRDELDVSNFAEEFTEMDPTYSPAALPQSSEKLFQGYSFVAPSILFKRNAAVIDPLQFHMGVERPGVTNVARSAMMKDSPFYQHYDLDLKDKPLGEGSFSICRKCVHKKSNQAFAVKIISKRMEANTQKEITALKLCEGHPNIVKLHEVFHD-----------------------------------------------------------------QLHTFLVMELLNGGELFERIKKKKHFSETEASYIMRKLVSAVSHMHDVGVVHRDLKPENLLFTDENDNLEIKIIDFGFARLKPPDNQPLKTPCFTLHYAAPELLNQNGYDESCDLWSLGVILYTMLSGQVPFQSHDRSLTCTSAVEIMKKIKKGDFSFEGEAWKNVSQEAKDLIQGLLTVDPNKRLKMSGLRYNEWLQDGSQLSSNPLMTPDILGSSGAAVHTCVKATFHAFNKYKREGFCLQNVDKAPLAKRRKMKKTSTSTETRSSSSESSHSSSSHSHG-KTTPTK---------------TLQPSNPADSNNPETLFQFSDSVA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FE05-1", "uniprot_id": "E7FE05_DANRE", "id": "E7FE05-1", "name": "Ribosomal protein S6 kinase", "aln": "MPSTMEGSSGEG-----------DLFTVKHELRNANLTGHVERVGIENFELLKVLGTGAYGKVFLVRKVSGHDSGKLYAMKVLKKATIVQKAKTAEHTRTERQVLEHIRQSPFLVTLHYAFQTDTKLHLILDYVNGGELFTHLVQRVRFKEQEVTLYSGEIVLALEHLHKLGIVYRDLKLENILLDSNGHIVLTDFGLSKEFH--EVERAYSICGTIEYMAPEIVAGGEGGHDKAVDWWSMGVLMYELLTGGSPFTVDGDENSHSDIAERIMKKDPPFPKDMGPLAKDIIQRLLIKDPKKRLGSGPSGAQNVKKHPFYQKLNWEDLAAKKVRAPFKPVIRDELDVSNFAEEFTEMDPTYSPAALPNNCDRIFQGYSFMAPSILFKRNAVMDDPAQLCGGSERPGSAAVARSAMMKDSPFYMNYEMDLRHNALGEGSFSICRQCTHKKTGQKYAVKIVSKRMEAQTQKEIAALKLCDGHPNIVKLHEIYHD-----------------------------------------------------------------QLHTYLVLELLRGGELLERIRRKQLFSETEASRIMRRLVSAVSHMHDVGVVHRDLKPENLLFTDDTENSEIKIIDFGFARLKPPDNQLLKTPCFTLQYAAPEILKYSGYDESCDLWSLGVILYTMLSGQVPFQCQGKSLMHTSAEEIMRKIKQGDFSFEGEAWRNVSSQAKDLIQELLTVDPDKRIKMCGLRYNTWLQDDSQLSSNPLMTPDILGSSTISVHSCVKATFNAFNKCKREGFRLQTVDKAPLAKRRKMKKTSTSTDTRSSSSESTHSSSSSSQSQDKTPTDGEMANLPQAPVSTPLTLGPDDEPSQGEPQPAFTFTQ---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .*.* . :*:*******.******.*:*************************:****:********************:****************************:*********:********* ** **.*:** :* ***************:***:************:*********** *.*****:*********:** **:.**********:**********.*******::**:::*:.**:*.:**:*::*..:***::****:********.** .*:::*:* *::*::*:******* *********************************:..:::******:**********.: ** *: * :*** : ************* :*::**:.:.**********:*.***:.* :****:******:*****:*****:**********::** ****:**:***.****:***::*: ******* ***:***************************:.:* ***:************** ********:*****:*. .**************************.:.:** *** ***:***:**********:***.:****** ******:**:**.***** ****.***************** :**:******:**** ***** **.*************:*****:********::**** *:. ..***. ** *.: .. .:*:. * *:: ", "identical_positions": 604, "similar_positions": 138, "identity": "68.4%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-696", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVM7-1", "uniprot_id": "DJC16_RAT", "id": "Q5FVM7-1", "name": "DnaJ homolog subfamily C member 16", "aln": "--------------------------------------------------------MELKRLS--------ISWQFLIVLVLILQSLSALDFDPYRVLGVSRTASQADIKKAYKKLAREWHPDKNKDPGAEDKFIQISKAYEILSNEEKRTNYDHYGDAGENQGYQ---QQREYRFRHFHEN-FYFDESFFHFPFNSERRDSIDEKYLLHFSHYVNEVVPDSFKKPYLIKITSDWCFSCIHIEPIWKEVVQELEGLGVGIGVVHAGYERRLAHHLGAHSTPSILGIINGKISFFHN-AVVHENLRQFVESLLPGNLVEKVTNKNYVRFLSGWQQENKPHALLFGQTPAAPLLYKLTAFAYKDYVSFGYVYVGLRGVEEMTRQYNVNIYAPTMLIFKEHINKPADAIQARGLKKQVIEDFITQNKYLLASRLTSQKLFHELCPVKRSHRQRKYCVVLLTAEANK--LSKPFDAFLSFALANTQDTVRFVHVYSSRQQEFASTLLPDIEAFQGKSGVSILERRNTAGRVVFKTLEDPWTGS------ESDKFVLLGYLDQLRKDPAFLSSEAVLPDLTDELAPVFLLRWLYSVSDYLSDFWESLLHSNWREMMPLLSLIFSALFILFGTVIVQAFSDSNEERESHPPDKEEVPEKAGKTEPSFTKES-SSKIPKKGFVEVTELTDVTYTSNLVRLRPGHMNVVLILSNSTKTSLLQKFALEVYTFTGSSSLHFSFLTLDKHREWLEYLLEFAQDAAP--IPNQYDKHFMERDYTGYVLALNGHKKYFCLFKPLK---------TVD-EETVGSC--DLDS------SRGKPPCG--LGPKPLKGKLSKLSLWMERLLEGSLQRFYIPSWPELD------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TN4-1", "uniprot_id": "DJC16_MOUSE", "id": "Q80TN4-1", "name": "DnaJ homolog subfamily C member 16", "aln": "--------------------------------------------------------MELKRLG--------VSWRFLMVLVLILQSLSALDFDPYRVLGVSRTASQADIKKAYKKLAREWHPDKNKDPGAEDRFIQISKAYEILSNEEKRTNYDHYGDAGENQGYQK--QQREHRFRHFHEN-FYFDESFFHFPFNAERRDSGDEKYLLHFSHYVNEVLPESFKRPYLIKITSDWCFSCIHIEPVWKEVVQELEGLGVGIGVVHAGYERRLAHHLGAHSTPSILGVISGKITFFHN-AVVHENLRQFVESLLPGNLVEKVTNKNYVRFLSGWQQENKPHALLFGQTPAVPLMYKLTAFAYKDYVSFGYVYVGLRGVEEMTRQYNVNLYTPTMLIFKEHINKPADVIQARGLKKQVIEDFIAQNKYLLASRLTSQRLFHELCPVKRSHRQRKYCVVLLTAETNK--VSKPFEAFLSFALANTQDTVRFVHVYSNRQQEFASTLLPDMEAFQGKSGVSILERRNTAGRVVFKTLEDPWTGS------ESDKFVLLGYLDQLRKDPAFLSSEAVLPDLTDELAPVFFLRWLYSVSDYLSDFWESLLHSNWREMMPLLSLIFSALFILFGTVMVQAFSDSNEERESHPADKEEVPEKAGKTEPSFTKES-SSKIPKKGFVEVTELTDVTYTSNLVRLRPGHMNVVLILSNSTKTSLLQKFALEVYTFTGSSSLHFSFLTLDKHREWLEYLLEFAQDAAP--IPNQYDKHFMERDYTGYVLALNGHKKYFCLFKPLK---------TVD-EETVASC--DPDS------SRGKPSCG--LGPKPLKGKLSKLSLWMERLLEGSLQRFYIPSWPELD------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2G8-1", "uniprot_id": "DJC16_HUMAN", "id": "Q9Y2G8-1", "name": "DnaJ homolog subfamily C member 16", "aln": "--------------------------------------------------------MEVRKLS--------ISWQFLIVLVLILQILSALDFDPYRVLGVSRTASQADIKKAYKKLAREWHPDKNKDPGAEDKFIQISKAYEILSNEEKRSNYDQYGDAGENQGYQKQQQQREYRFRHFHEN-FYFDESFFHFPFNSERRDSIDEKYLLHFSHYVNEVVPDSFKKPYLIKITSDWCFSCIHIEPVWKEVIQELEELGVGIGVVHAGYERRLAHHLGAHSTPSILGIINGKISFFHN-AVVRENLRQFVESLLPGNLVEKVTNKNYVRFLSGWQQENKPHVLLFDQTPIVPLLYKLTAFAYKDYLSFGYVYVGLRGTEEMTRRYNINIYAPTLLVFKEHINRPADVIQARGMKKQIIDDFITRNKYLLAARLTSQKLFHELCPVKRSHRQRKYCVVLLTAETTK--LSKPFEAFLSFALANTQDTVRFVHVYSNRQQEFADTLLPDSEAFQGKSAVSILERRNTAGRVVYKTLEDPWIGS------ESDKFILLGYLDQLRKDPALLSSEAVLPDLTDELAPVFLLRWFYSASDYISDCWDSIFHNNWREMMPLLSLIFSALFILFGTVIVQAFSDSNDERESSPPEKEEAQEKTGKTEPSFTKEN-SSKIPKKGFVEVTELTDVTYTSNLVRLRPGHMNVVLILSNSTKTSLLQKFALEVYTFTGSSCLHFSFLSLDKHREWLEYLLEFAQDAAP--IPNQYDKHFMERDYTGYVLALNGHKKYFCLFKPQK---------TVEEEEAIGSCS-DVDSSLYLGESRGKPSCG--LGSRPIKGKLSKLSLWMERLLEGSLQRFYIPSWPELD------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GRJ6-1", "uniprot_id": "A0AC58GRJ6_DANRE", "id": "A0AC58GRJ6-1", "name": "DnaJ homolog subfamily C member 16", "aln": "MTFIIEIVYPEALTTGSTGEAKAWGDDPSITTGKTWIVAKFWIDTITTRVVSSLSQFMYQKMGGWSVFVSCCAWAILLLALFGDSLASAPEFDPYRVLGVSKHASLTEIKKMYKKLAREWHPDKNKSPGAEDMFIKITKSYEILSNEERRANYDRFGQMDENQNFAR----PPQGFRQYHDS-FYFDESFFHFPRTS--RDFTESKHLLHYNQYMNEVLPDSFKRPYLIKITSEWCFTCIHIEPVWKDTVLELEPLGVGIGVVDIGYERQLANHLGAHRTPSILGLVNGKVTFFHY-SVVREHLRQFVESLLPQRLVEKVTDSNYLEFLNSWHEENKPRVIMFDIASNVPLLYKLTAFAYKDYVRFGYVDMGLTETSKVVQRFNINTYAPTMLLFKENTEKPADVIQARGMKKQILDEFVSNNRFLLVPRLVNQKLFDELCPVKQFHRRRKYCVLLVTGEGEQ--FVSVNEAFFDFASSNTKEVLRFAYVDQRQQQPLCDTLLKKDDTTP--PQVIILERRSTSGRVLYRTVTGGWNGS------DDDKHRLHEQLELLQRDPSYLTHDAMLPELNNEFASMFLIQWINTAYDYLAQFYFDLLYSNWREMMPVLSLIFSALFILFGTVIIQAFSDSGEEK----PTKQKATESPKTPESSPGPESTSSRPPKKNFVEVTELTDITYMSNLVRLKPGHINVVLILTDASKQVLLRKFAKEVYSFSGSQNLHYSFLNVDKHRQWMDSLMESAPDARSDEEEEVEDPSTNKSDHTGHVLALNGHKKYFCVFRPVF---------TGEEAERSRYSDDDAATGGTSRTSRSRSSSRQKATTLEIHHKLDRLGLWMERLMEGTLPRHYVSAWPGMDTITPQK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7PLG1-1", "uniprot_id": "Q7PLG1_DROME", "id": "Q7PLG1-1", "name": "DnaJ homolog subfamily C member 16", "aln": "--------------------------------------------------------MISCLISN-------YIITILVLCTTSYIHVCSSLNDPYAILGINKKATTYEIREAYKELAKKWHPDKVKNDYGAEKFIQIKLAYEILADLDRRRIFDRYGVSDINSQYFQ----KKHDYSEYNRFTLNQNDDDFGQRFDIKQDIAFYQKLSITENYFEKMILSKNAKKVHVVMFYNDWCFKCTRIVDAFKKILELLQPIGINFATVNAVHEESVFRKCGAREVPQLVLILDNQYFLYRDHSFTPQKVVEFIRKKIPFNVFKRIEHDNFNDFLGGWS-DNRARALIFEPRSLTRLRYLLTAFEFYDRVAFGFVNTISKDSSNIITRFKVNTSLDTLILFNEDTTTFTASVCMEEIPNHILVNMVSTNQFLAFPRISSQNIMESVCPTEWNRQRKHLCVILITENNRKKDFERVALRNIALSVGYNSEKVRFAYIFKESQPDFIKSISKGSFKDSLIEIVIIWRRDKKRIKYNWVYVAKQNGNSSPEHLMNSTKDQISNAVKKLLKNSEALCYEAIVENLFNEHSQGILTKWIS-QFLYVVDYLSDNIED--EHLLAVFSLLGTIAFMFTVGYVLIYFVR--------------VEEKYLKAHGHLIDIQDQRHINLIPELKLYELRAEKYNGMVRLLKPGCRTLLLINDCQSRHKLIPYFHKAVWPYRKSKTLLFGHMVIERGLPWFAEILRLSLSKNR-------HLQVNPRNCVGTVLALNGHRKYFCMYHAKHPESALGTKRTLKNTQKLLDANEDPEIGTFLKRDFSEESESE-PNILLEDNLLNGLDNWLERLFDGRTQKYYINYWPDFITK----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. :*:: .: *** :**:.: *: :*:: **:**::***** *. . : **:*. :****:: ::* :*::* . *. : : .:: : ::. * .* : . : : ::... *: ::: : .:***.* :* :*. : *: :*:.:..*. :*. : .: **: .*.:: ::..: ::: :.. ::: :*:.. :* .:.::: ..*: **..* :*:.:.::* . . * * **** : * : **:* .:: ::::* *:::*:*. : : . : :::: :::: *::* .*: .*.::..:**.: ::::: **:*:* : : . : :: . ..: :**.:: . * : .:: * * .* .. : : : .* :. * : :. * ::. * :*:: :* :* : :: :*: *: : . : . ..::.::**: : *:: :: * . *. ... . . : ::: ** .* . : *:** .::** :: *: * *:.: *. * :..: ::: *: ::. : . . : .* *******:****:::. * . : . * . .. . . *. *. *:***::* :.*: ** : ", "identical_positions": 135, "similar_positions": 294, "identity": "15.39%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-697", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49023-1", "uniprot_id": "PAXI_HUMAN", "id": "P49023-1", "name": "Paxillin", "aln": "------------------------------------------MDDLDALLADLESTTSHISKRPVFLSEETPYSYPTGNHTYQEIAVPPPVPPPPSSEALNGTILDPLDQWQPSSSRFIHQQPQSSSPVYGSSAKTSSVSNPQDSVGSPCSRVGEEEHVYSFPNKQK--SAEPSPTVMSTSLGSNLSELDRLLLELNAVQHNPPGFPA-----------------------------DEANSSPPLPGALSPLYGVPETNSPLGGKAGPLTKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKIQGLEQRA------------------------DGERCWAAGWPRDGGRSSPGGQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DEGGFMAQGKTGSSSP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGGPPKP-------------------------------------------------GSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLFC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VI36-1", "uniprot_id": "PAXI_MOUSE", "id": "Q8VI36-1", "name": "Paxillin", "aln": "------------------------------------------MDDLDALLADLESTTSHISKRPVFLSEEPPYSYPTGNHTYQEIAVPPPVPPPPSSEALNGTVLDPLDQWQPSGSRYAHQQPPSPLPVYSSSAKNSSASNTQDGVGSLCSRAGEEEHVYSFPNKQK--SAEPSPTVMSSSLGSNLSELDRLLLELNAVQHSPPGFPA-----------------------------DEAESSPPLPGALSPLYGIPENNTPLGGKAGPLVKEKPKRNGGRGLEDVRPSVESLLDELESSVPSPVPAITVNQGEMSSPQRVTSSQQQTRISASSATRELDELMASLSDFKMQGLEQRV------------------------DGERPWAAGWPPSSRQSSPEGQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DEGGFMAQGKTGSSSP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGGLSKP-------------------------------------------------GSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHSLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQSCFVKLFC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66H76-1", "uniprot_id": "PAXI_RAT", "id": "Q66H76-1", "name": "Paxillin", "aln": "------------------------------------------MDDLDALLADLESTTSHISKRPVFLSEEPPYSYPTGNHTYQEIAVPPPVPPPPSSEALNGTVLDPLDQWQPSGSRYAHQQPPSPSPIYSSSTKNSSASNPQDSVGSLCSRAGEEEHVYSFPNKQK--SAEPSPTVMSSSLGSNLSELDRLLLELNAVQRSPSGFSAGMVSVQASREPLGSWGTEGRAIILSPFFQDEAESSPPLPGALSPLYGVPESNNLLGGKAGPLMKEKPKRNGGRGLEDVRPSVESLLDELENSVPSPVPAITVNQGEMSSPQRVTSSQQQTRISASSATRELDELMASLSDFK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FMAQGKTGSSSP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGGLSKP-------------------------------------------------GSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHSLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQSCFLKLFC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9Q9X1-1", "uniprot_id": "A0A8M9Q9X1_DANRE", "id": "A0A8M9Q9X1-1", "name": "", "aln": "MTGVCCVFLPFTLSLFLSHTLIHTHVYTHTQVGLNTGTHSGILSKLYALLADLESSTAHISKCPVFLPEETPYSYPSGGQLFQDDSPPPPLPPPPSAEALNGSLSPRPDSQQSLG-----------------SVQKSTLS--RDSS-PPASRT-EEDHVYSFPNKQK--HSDSSATAMTSALGSNLSELDRLLLELNAVQQNAPSYST------------------------------TEDAAPPLP-PCSVAHYIQENGAHPSITLTPAAQDKPQRNGTKGTDDGRPTVESLLNELESSVPSTTPSPCALTSNLTDGQLDAPSEQQGRISATSATRELEELMACLSDFKVQSNPSSLGSLNSEPLFEQTTTTAEIHPPPTTTVSKSLSPTLPAESRQFSPGPSSFELHIVEDSGEPGAVPLPSNGVFKSYSRLSPPPASSPRFSPAPDLGLDSAIDVSASLLSSEVESLVVLSQTIPMTSAPRGQYLSPVREGSPSAKLMNSGLNSYSPNTKSPSPRSSPAISRVNERVSPLMTPASIDLYLSRPETKPLSPVPSLPRSPLPAVSESSFLSLPKALSPPPIIPTSPTLGVSKSPSPKQESAYLEPVVSLKPHLEPPTYEPSLDDALDKLLAMSFSRPENETHITASASSQLTSEAQPEIYEESIVAADRSDIHPDTHTESEMGDGLLEDQSDCRSDLDWADMELKMAYEGPDGSMTPMTEASWMDDSLTPSSCPGTPDAQMDLPMLHMAGTMDRISASGHIKSVIRRTKEIQNVHPMYRDGLIRRKMGPLIFHKSNSQDRLIEELQGKLGIARKEKAKKQQPDDWLTEGVIVMSNPKRSREDHNRDVDKIIIPPESPLPQRKMILPPQSPPMPRPPPPAEEPKCPPVVKLAPAPLPPPPPPAPSPPPREPTPPPQPTLPPVPPKPPTPEPVVVPAPSPKPKPAPPPSPIPPPAPVSPPKVLASVGCQTEYDPLFPPLQIMAQGKGPHGQANKLDNMLGSLQSDLHKLGVQTVAKGVCGACSKPIVGQVVTAMGRTWHPEHFVCTHCQEEIGSRNFFEREGQPYCERDYHHLFSPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDLFAPKCGGCARAILENYISALSSLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHARRGSLCSGCQKPITGRCITAMGKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQGCFIKLFS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2PDT4-1", "uniprot_id": "Q2PDT4_DROME", "id": "Q2PDT4-1", "name": "", "aln": "------------------------------------------MDR--TMYGKIDPGARQPYRTARSKGILPGYALLADLQNSVPGQPQQPQPQYGTVQPKHQALQQQQFVDNTPG---------------YGSLRGKAQPQVYQEHYSVETRSPTAGHDFNGSSTTPGYANQGSLPRQAAGASTGLSELDSLLQDLQKID-VPVNYSTPVS------------------------KYNTMNSYATVEERPSVDSLLKELDNAHIYAVPNGSAHKSPTPGRHVTITVRETKTEKLTGPDGPVG-TVEEQIVQQKDSYTPNHAVPGQQVHQAYTSQATKELDDLMASLSDFKVSNGTNGIG-----------------------NGSHPQQHSSTVQHQTVTDYAR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PNKGSQQAHLTQTIEETT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IVEDSRE--------------------------------------------------DQLDSMLGNLQANMSRQGVNTVQKGCCNACEKPIVGQVITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFSPRCAYCNGAILDKCVTALDKTWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKCNGCNRAIMENYISALNSQWHPDCFVCRDCRQPFQGGSFFDHEGLPYCETHYHAKRGSLCAGCSKPITGRCITAMFKKFHPEHFVCAFCLKQLNKGTFKEQKDKPYCHTCFDKIFG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :: ..::. : : : . . *: :. : * * : :. : :: :. . * : .: . : . :* * :. ... : * . ::. .:.***** ** :*: :: . .:.: :: ..: * : * . .*. * : * : . * :..* .. . : : .. :* : ::.**:**::***.***** : : :: .: .:**.***.**::: : ** ** ** *.**.***.***:**:*:*******.*.**.:*:*:******:* **** *** ****** ****.**** *****:***.********* ** *****:***.***:***::*****.** ***:*******.: ***:*****:* ** .****:*:* ****.*** :*****:**.*********** *************************:*****: ** *:* ", "identical_positions": 226, "similar_positions": 138, "identity": "18.07%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-700", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O15083-1", "uniprot_id": "ERC2_HUMAN", "id": "O15083-1", "name": "ERC protein 2", "aln": "--MYGSARTITNLEGSPSRSPRLPRSPRLGHRRTS-SGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEG----VAST-TYPKG-TMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLTGSSHHHHHQVPSMLRQVR---DSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQ---------HLQLTIQALQDELRTQRDLNHLLQQESGNR--GAEHFT-IELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSK----------------------------------------------------------------------------------------------------------GLPSKS--------------LEDDNERTRRMAEAESQVSHLEVILDQK------------------------------------EKENIHLREELHRRSQ---------LQPEPAKTKALQTVIEMKDTKIASLERN------------------------------------------------------------------------------------------------------------------------------IRDLEDEIQMLKANGVLNTE---------------------------------DREEEIKQIEVYKSHSKFMKTK-----------------------------IDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECSKLEAQLK---------------KAHNIEDD----------SRMNPEFADQIKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELES---LTLR---------------------------------------------HMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKAR-----------------------LASTQQSLAEKEAHLANLRIERR------KQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKD--------------------RLVHQLKQQTQNRMKLMADNYDDDHHHYHH------------------------------------------------------------------------------------------------------------------------------------HHHHH----------------HHRSPGRSQ-------------------------------------------------HSNHRPSPDQDDEEGIWA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PH08-1", "uniprot_id": "ERC2_MOUSE", "id": "Q6PH08-1", "name": "ERC protein 2", "aln": "--MYGSARTISNLEGSPSRSPRLPRSPRLGHRRTS-SGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEG----VAST-TYPKG-TMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLSGSSHHHHHQVPSMLRQVR---DSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQ---------HLQLTIQALQDELRTQRDLNHLLQQESGNR--GAEHFT-IELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSK----------------------------------------------------------------------------------------------------------GLPSKS--------------LEDDNERTRRMAEAESQVSHLEVILDQK------------------------------------EKENIHLREELHRRSQ---------LQPEPAKTKALQTVIEMKDTKIASLERN------------------------------------------------------------------------------------------------------------------------------IRDLEDEVQMLKANGVLNTE---------------------------------DREEEIKQIEVYKSHSKFMKTK-----------------------------IDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLK---------------KAHNIEDD----------SRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELES---LTLR---------------------------------------------HMKDQNKKVANLKYNQQLEKKKNAQLLEEVRRREDSMVDNSQHLQIEELMNALEKTRQELDATKAR-----------------------LASTQQSLAEKEAHLANLRIERR------KQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKD--------------------RLVHQLKQQTQNRMKLMADNYDEDHHHYHH------------------------------------------------------------------------------------------------------------------------------------HHHHH----------------HHRSPGRSQ-------------------------------------------------HSNHRPSPDQDDEEGIWA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K3M6-1", "uniprot_id": "ERC2_RAT", "id": "Q8K3M6-1", "name": "ERC protein 2", "aln": "--MYGSARTISNPEGSPSRSPRLPRSPRLGHRRTS-SGGGGGTGKTLSMENIQSLNAAYATSGPMYLSDHEG----VAST-TYPKG-TMTLGRATNRAVYGGRVTAMGSSPNIASAGLSHTDVLSYTDQHGGLGGSSHHHHHQVPSMLRQVR---DSTMLDLQAQLKELQRENDLLRKELDIKDSKLGSSMNSIKTFWSPELKKERVLRKEEAARMSVLKEQMRVSHEENQ---------HLQLTIQALQDELRTQRDLNHLLQQESGNR--GAEHFT-IELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLNARDESIKKLLEMLQSK----------------------------------------------------------------------------------------------------------GLPSKS--------------LEDDNERTRRMAEAESQVSHLEVILDQK------------------------------------EKENIHLREELHRRSQ---------LQPEPAKTKALQTVIEMKDTKIASLERN------------------------------------------------------------------------------------------------------------------------------IRDLEDEIQMLKANGVLNTE---------------------------------DREEEIKQIEVYKSHSKFMKTK-----------------------------NDQLKQELSKKESELLALQTKLETLSNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLTNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQRERDDRERLEEIESFRKENKDLKEKVNALQAELTEKESSLIDLKEHASSLASAGLKRDSKLKSLEIAIEQKKEECNKLEAQLK---------------KAHNIEDD----------SRMNPEFADRLKQLDKEASYYRDECGKAQAEVDRLLEILKEVENEKNDKDKKIAELES---LTLR---------------------------------------------HMKDQNKKVANLKHNQQLEKKKNAQLLEEVRRREFSMVDNSQHLQIEELMNALEKTRQELDATKAR-----------------------LASTQQSLAEKEAHLANLRMERR------KQLEEILEMKQEALLAAISEKDANIALLELSASKKKKTQEEVMALKREKD--------------------RLVHQLKQQTQNRMKLMADNYDDDHHHYHH------------------------------------------------------------------------------------------------------------------------------------HHHHH----------------HHRSPGRSQ-------------------------------------------------HSNHRPSPDQDDEEGIWA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AB32U3W7-1", "uniprot_id": "A0AB32U3W7_DANRE", "id": "A0AB32U3W7-1", "name": "", "aln": "--MYGSARAVGHIEGSPARSPRLPRSPRLGHRRAN-SSSSG--GKTLSMENIQSLNAAYATSGPMYLSDHEG----VGSTATYPKG-TMTLGRATSRAMYGGRVTAMGSTPNIATVGIPHADLQSYGDLG---SLSLLHHQGTPSALLRQVVRGGGGELLELQAQLRDMQRENELLRRELDLKDSKLGSSTNSIKSFWSPELKKERIMRKEEAARTSILKEQMRVTHEENQHLLDSRRTKHLQLTIQALQDELRTQRDLNHLLQQESSSRAGGGDHFTTIELTEENFRRLQAEHDRQAKELFLLRKTLEEMELRIETQKQTLGARDESIKKLLEMLQSK----------------------------------------------------------------------------------------------------------GLPPASGR----------ASDEEEQERARRIAEAEAQLGHLEVILDQK------------------------------------EKENIHLREELHRRNQ---------LHPDPGKTKALQTIIEMKDTKIASLERN------------------------------------------------------------------------------------------------------------------------------IRDLEDEIQMLKANGLLNTE---------------------------------DREEEIKQMEVYKNHSKFMKTK-----------------------------IDQLKQELSKKESELLALQTKLETLNNQNSDCKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKESFLNKKTKQLQDLTEEKGTLAGEIRDMKDMLEVKERKINVLQKKIENLQEQLRDKDKQLGNLKDRVKSLQTDSSNTDTALATLEEALSEKERIIERLKEQREREDRERMEELDSYKKENKDLKEKVNTLQVELTEKESSLIDLKEHASSLASSGLKKDSKLKSLEIAIEQKKEECNKLETQLQKQAEQLF--SQMNNPKAHEVEVQQ--------SSRGNPEYVDRVKLLEKEVSYFKDESSKAQNEVERLLEILREVETEKNDKDKKIQELESPPPLATRPSPRPGGRAPSDPPPSVSAAPQQIGGMV-----------WDFLGKQTKDQIKKGPGIKLGPQMDKKGPGNILQDQRK--DNPMDNP---KMEELMNVLEKTRQELDATKQR-----------------------LSSTQQSLSERDGHLTNLRQERR------KQLEEILEMKQQALLAAISEKDANIALLELSSSNKKKTQEEVLALKREKD--------------------RLMHQLKQQTQSRMKLIADNYEDDHYHPHAPPPHMQPQPLHPQPQPQPPYPQGPHPHQPPYPHAPHPQHPQPPPHHPQHLQQPQPPGPHPPRPQQPHPQHQQHPQHQQHPQHPQHPQHPQHPQHPHPGIPPQQQQQHPHLQHPHGPPPQQGPHPPQPMPHPQQHPHHPPHPGPQGPHPRHPPPHHRGPGRGQP------------------------------------------------HPGHRPSPDQDDEEGIWA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K7K9-1", "uniprot_id": "ERC_DROME", "id": "A0A0B4K7K9-1", "name": "Protein bruchpilot", "aln": "MSRDDYNPVTSSGVRSPGRVRRLQELPTVDRSPSRDYGAPRGSPLAMGSPYYRDMDEPTSPAGAGHHRSRSASRPPMAHAMDYPRTRYQSLDRGGLVDPHDREFIPIREPRDRSRDRSLERGLYLEDELYGRSARQSPSAMGGYNTGMGPTS--DRAYLGDLQHQNTDLQRELGNLKRELELTNQKLGSSMHSIKTFWSPELKKERALRKEESAKYSLINDQLKLLSTENQ---------KQAMLVRQLEEELRLRMRQPNLEMQQ-------------------QMEAIYAENDHLQREISILRETIKDLECRVETQKQTLIARDESIKKLLEMLQAKGMGKEEERQMFQQMQAMAQKQMYNNYTGASGSSPPLPDIIGQYYGPGSLGPGPLSYGSGNGYGPPGYDLYGPSTSTAAGGYGLYDPQIYGPCQQTSPIRRRRYSIAGLPSATMYNDVYGYPAPPLQQTSSSNIVNLLNEAHKSISRSSQILNLTNQARQLGQLVTTPLGGGGVGMGLGRVVSSYPTLHPGDTSPPYLNDNLMQMSTSFSSQPNMYFQPQAQVQQVLPTQLTAAQSAAAAAARLRPAYSVTNLVSSYPTTTAAGYGCKYGGYGNPYQSDLGYGNPLAPFQQRQLMAHQSLHASNPAISQYYQNQGAATGTGASAAALAYNLQQQFAGTQHYGGGSQGPPLGHSHIQASVQQQMHPQYQYHVHQHQNHLQTHPLAALANTSGPFGGTLASSARDYVDGLHHAAHSHTHPHSHPHHSSHHSHHTAYPHSHSHHQQQQPHQAHHHHHLPYSKLDLDYPKLPQEHKRQLDEFRLEIQRRDQEILAMAAKMKTLEEQHQDYQRHIAVLKESLCAKEEHYNMLQTDVEEMRARLEEKNRLIEKKTQGTLQTVQERNRLTSELTELKDHMDIKDRKISVLQRKIENLEDLLKEKDNQVDMARARLSAMQAHHSSSEGALTSLEEAIGDKEKQMAQLRDQRDRAEHEKQEERDLHEREVADYKIKLRAAESEVEKLQTRLERAVTERERLEIKLEASQSELGKSKAELEKATCEMGRSSADWESTKQRIARLELENERLKHDLERSQNVQKLMFETGKISTTFGRTTMTTSQELDRAQERADKASAELRRTQAELRVTQSDAERAREEAAALQEKLEKSQGEVYRLKAKLENAQGEQESLRQELEKAQSGVSRIHADRDRAFSEVEKIKEEMERTQATLGKSQLQHEKLQNSLDKAQNEVDHLQDKLDKACTENRRLVLEKEKLTYDYDNLQSQLDKALGQAARMQKERETLSLDTDRIREKLEKTQVQLGRIQKERDQFSDELETLKERSESAQTLLMKAARDREAMQTDLEVLKERYEKSHAIQQKLQMERDDAVTEVEILKEKLDKALYASQKLIDEKDTSNKEFEKMLEKYDRAQNEIYRLQSRCDTAEADRARLEVEAERSGLAASKAREDLRKLQDESTRLQEACDRAALQLSRAKECEDNARSELEHSRDRFDKLQTDIRRAQGEKEHFQSELERVTYELERAHAAQTKASASVEAAKEEAAHYAVELEKMRDRYEKSQVELRKLQDTDTFGRETRRLKEENERLREKLDKTLMELETIRGKSQYESESFEKYKDKYEKIEMEVQNMESKLHETSLQLELSKGEVAKMLANQEKQRSELERAHIEREKARDKHEKLLKEVDRLRLQQSSVSPGDPVRASTSSSSALSAGERQEIDRLRDRLEKALQSRDATELEAGRLAKELEKAQMHLAKQQENTESTRIEFERMGAELGRLHDRLEKAEAEREALRQANRSGGAGAAPHPQLEKHVQKLESDVKQLAMEREQLVLQLEKSQEILMNFQKELQNAEAELQKTREENRKLRNGHQVPPVAAPPAGPSPAEFQAMQKEIQTLQQKLQESERALQAAGPQQAQAAAAAGASREEIEQWRKVIEQEKSRADMADKAAQEMHKRIQLMDQHIKDQHAQMQKMQQQMQQQQQAAQQAVQQAAQQQQSAAGAGGADPKELEKVRGELQAACTERDRFQQQLELLVTELEKSKMSNQEQAKQLQTAQQQVQQLQQQVQQLQQQMQQLQQAASAGAGATDVQRQQLEQQQKQLEEVRKQIDNQAKATEGERKIIDEQRKQIDAKRKDIEEKEKKMAEFDVQLRKRKEQMDQLEKSLQTQGGGAAAAGELNKKLMDTQRQLEACVKELQNTKEEHKKAATETERLLQLVQMSQEEQNAKEKTIMDLQQALKIAQAKVKQAQTQQQQQQDAGPAGFLKSFF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . **.* ** . * :.: : .. ::. :.:: . :.:*. : .:.. :. : **: :*.*. :. .. .: .. : : . .: : . : : . . : :** * ::*** *::**::.:.***** :***:********** :****:*: *::::*::: *** : : :: *::*** : :* *: ::. : **:*: :*: :**:*::::* *:******* **************:* ***. : ...: .. : **. .:.: . **: . :.. :*.::* : . ::*:. :.* * : :: *: * ::: ::.:* .: **. . ... :: :.**:. : : *::: *:.:::.*:**: :*::**.:*:.* ::** ****** ***:: :***:*: :* *****: :::***: : .:*:. *:.*: ::** :::*:***.***:*****:: *::**:*: : *:.::*:. *.:: **::****:.:**: : :*::**:* ::*: ** : ..:* * * *:.: : *: : :: * . . * :*:* . : :*: . * .: .:: : *::* . .: .. : .:* . ::...**. *: * *: .:.: : :: *:. : : *:: :: *:::: : *:. :. *: *: .*** : * : : ::.* : : :* .:: ** : *:* * * *: * :::* : **: .. :*:: *: *:* : : : *: ::..:: : ::*: : . : : .: . * . * : *..* : : .:* * ", "identical_positions": 231, "similar_positions": 365, "identity": "10.19%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-705", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BG02-1", "uniprot_id": "2ABG_MOUSE", "id": "Q8BG02-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform", "aln": "---------------------------------------------------------MGEDTDTRKINHSFLR-DHSYVTEADVISTVEFNHTGELLATGDKGGRVVIFQREPESKNAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITER----------------DKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRTFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYESDCIFDKFECAWNGSDSVIMTGAYNNFFRMFD------------------------------------------------RNTKRDVTLEASRESSKP------------------RAVLKPRRVCVGGKRR--------RDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQDKVNSDMH------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P97888-1", "uniprot_id": "2ABG_RAT", "id": "P97888-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform", "aln": "---------------------------------------------------------MGEDTDTRKINHSFLR-DHSYVTEADVISTVEFNHTGELLATGDKGGRVVIFQREPESKNAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITER----------------DKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYESDCIFDKFECAWNGSDSVIMTGAYNNFFRMFD------------------------------------------------RNTKRDVTLEASRESSKP------------------RAVLKPRRVCVGGKRR--------RDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQDKVNSDMH------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2T4-1", "uniprot_id": "2ABG_HUMAN", "id": "Q9Y2T4-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform", "aln": "---------------------------------------------------------MGEDTDTRKINHSFLR-DHSYVTEADIISTVEFNHTGELLATGDKGGRVVIFQREPESKNAPHSQGEYDVYSTFQSHEPEFDYLKSLEIEEKINKIKWLPQQNAAHSLLSTNDKTIKLWKITER----------------DKRPEGYNLKDEEGKLKDLSTVTSLQVPVLKPMDLMVEVSPRRIFANGHTYHINSISVNSDCETYMSADDLRINLWHLAITDRSFNIVDIKPANMEDLTEVITASEFHPHHCNLFVYSSSKGSLRLCDMRAAALCDKHSKLFEEPEDPSNRSFFSEIISSVSDVKFSHSGRYMLTRDYLTVKVWDLNMEARPIETYQVHDYLRSKLCSLYENDCIFDKFECAWNGSDSVIMTGAYNNFFRMFD------------------------------------------------RNTKRDVTLEASRESSKP------------------RAVLKPRRVCVGGKRR--------RDDISVDSLDFTKKILHTAWHPAENIIAIAATNNLYIFQDKVNSDMH------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5I6-1", "uniprot_id": "A0ACD6B5I6_DANRE", "id": "A0ACD6B5I6-1", "name": "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B", "aln": "-------------------------------------------------------------MLSPVLCSDLAA-LEPEYTDADVISTVEFNQTGEFLATGDKGGRVVIFQREP--------LGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLPPHNPAHFLLTTNDKTVKLWKVSER----------------DKRAEGYNLRDEEGRLKDLSTITTLQVPVLRPMDLLVEASPRRVFANAHAYHINSISVNSDCETYLSADDLRINLWHLSITDRSFNIVDLKPENMEDMSEVITVAEFHPHHCHLLAFSSSTGTTRLCDMRARALCDQHAKLFEEAVDPTRRSFFSEIVSSVSDVKFSHSGRYLLTRDYLTVKVWDLNMENKPVEVYQVHDYLRTKLCSLYESDCIFDKFECAWNGTDSVIMTGAYNNYFRMFD------------------------------------------------RASRRDVTLEASREVCKR------------------RAVLQPRRVCVGKKRK--------ETDVSVDSLDFRKKILHTAWHPKENIIAIAASNNLYIFQDRLTPNGHHNTPEIQSAPPK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36872-1", "uniprot_id": "2ABA_DROME", "id": "P36872-1", "name": "Protein phosphatase PP2A 55 kDa regulatory subunit", "aln": "MGRWGRQSPVLEPPDPQMQTTPPPPTLPPRTFMRQSSITKIGNMLNTAININGAKKPASNGEASWCFSQIKGA-LDDDVTDADIISCVEFNHDGELLATGDKGGRVVIFQRDPASKAANPRRGEYNVYSTFQSHEPEFDYLKSLEIEEKINKIRWLQQKNPVHFLLSTNDKTVKLWKVSER----------------DKSFGGYNTKEENGLIRDPQNVTALRVPSVKQIPLLVEASPRRTFANAHTYHINSISVNSDQETFLSADDLRINLWHLEVVNQSYNIVDIKPTNMEELTEVITAAEFHPTECNVFVYSSSKGTIRLCDMRSAALCDRHSKQFEEPENPTNRSFFSEIISSISDVKLSNSGRYMISRDYLSIKVWDLHMETKPIETYPVHEYLRAKLCSLYENDCIFDKFECCWNGKDSSIMTGSYNNFFRVFD------------------------------------------------RNSKKDVTLEASRDIIKP------------------KTVLKPRKVCTGGKRK--------KDEISVDCLDFNKKILHTAWHPEENIIAVAATNNLFIFQDKF-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q00362-1", "uniprot_id": "2ABA_YEAST", "id": "Q00362-1", "name": "Protein phosphatase PP2A regulatory subunit B", "aln": "---------------------------------------------------------MAQNNFDFKFSQCFGDKADIVVTEADLITAVEFDYTGNYLATGDKGGRVVLFERSNS------RHCEYKFLTEFQSHDAEFDYLKSLEIEEKINEIKWLRPTQRSHFLLSTNDKTIKLWKVYEKNIKLVSQNNLTEGVTFAKKGKPDNHNSRGGSVRAVLSLQSLKLPQLSQHDKIIAATPKRIYSNAHTYHINSISLNSDQETFLSADDLRINLWNLDIPDQSFNIVDIKPTNMEELTEVITSAEFHPQECNLFMYSSSKGTIKLCDMRQNSLCDNKTKTFEEYLDPINHNFFTEITSSISDIKFSPNGRYIASRDYLTVKIWDVNMDNKPLKTINIHEQLKERLSDTYENDAIFDKFEVNFSGDSSSVMTGSYNNNFMIYPNVVTSGDNDNGIVKTFDEHNAPNSNSNKNIHNSIQNKDSSSSGNSHKRRSNGRNTGMVGSSNSSRSSIAGGEGANSEDSGTEMNEIVLQADKTAFRNKRYGSLAQRSARNKDWGDDIDFKKNILHFSWHPRENSIAVAATNNLFIFSAL------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *:**:*: ***: *: ***********:*:*. **.. : ****:.***************:*:** : * **:*****:****: *: * * ... * :: .: :*::* : :: .:*:* ::*.*:*******:*** **::**********:* : ::*:****:** ***:::**** :**** .*::: :***.*: :***** :***.::* *** :* .:.**:** **:**:*:* .***: :****::*:**::*: :*::. :*: *: :*.. **.*.****** :.* .* :***:*** * :: * . ::. : .* : : . **:. :.. ** . . * :** *:*** :*** ** **:**:***:**. ", "identical_positions": 196, "similar_positions": 126, "identity": "32.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-708", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIL5-1", "uniprot_id": "TULP4_MOUSE", "id": "Q9JIL5-1", "name": "Tubby-related protein 4", "aln": "-------------MYAAVEHGPVLCSDSNILCLSWKGRVPKSEKEKP---VCRRRYYEEGWLATGNGRGVVGVTFTSSHCRRDRSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGILSMSWNYPIFLVEDSSESDTDSDDYSPPQDGPAAYPIPVQNTKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLK---EVVAQWCTQGDLLAVAGMEQQAQLSELPNGP---LLKSAMVKFYNVRGEHIFTLDTLVQRP-IISICWGHRDSRLLMASGPALYVVRVEHRVSSLQLLCQQAIASTLREDKDVNKLTLPPRLCSYLSTAFIPTIKPPIPDPNNMRDFVSYPSAGNERLHCTMKRTEDDPEVG-GPCYTLYLEYLGGLVPILKGRRISKLRPEFVIMDPRTDSKSDEIYGNSLISTVIDSCNCSDSSDIELSDDWAAKKSPKISRSSKSPKLP------RISIEARKSPKLPRAAQEISRSPRLPMRKPSMGSPSLTRREFPFEDITQHNYLAQVTSNIWGTKFKIVGLAAFLPTNLGAVIYKTSLLHLQPRQMTIYLPEVRKISMDYINLPVFNPNVFSEDEDDLPVTGASGVPENNPPCTVNIPIAPIHSSAQALSPTQSIGLVQSLLANQNVQLDVLTNQTTAVGSAEHAGDAAT---------------------------QYPVSSRYSNPGQVIFGGVEMGRIIQ---NPPQLPLPPPPPPPPQAP---------------------------------------------------------------------------------------------------------------------------------------------------------MQLSAVDHGDR----------------DHEHLQKSAK----------------------------------------------------ALRPVP---------------------------------QLAAEGDAVVFSAPQEVQVAKMNPPPPYPGTIP---AAPTTAAPPPPLPPPQP----PVDVCLKKGDFSLYPTAAHYQPPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATE-KKVPQPCTSATLNRLTVPRYSIPTGDPPPYPEIASQLAQGRSAAQRLDNSLIHATLRRNNREVALKMAQLADSSRAPLQPLAKPKGGAAGAVAQLPARPPPALYTCSQCSG------------------------------AGPSSQSGAALAHAISTSPLASQSSYNLLSPPDTSRDRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTMKRPPPYQWDPMLGEDVWVPQERTAQPTVPNPLKLSPLMLGQGQHLDVARVPFVP--PKSPSSPTATFPTGYGMGM-PYPGSYNN--PSLPGVQAP---CSPKDALSQAQFAQQESAVVLQPAYP---PSLS---YCTLPPTYPGSSTCSSVQLPPIALHPWNSYSTCPPMQNTQGTLPPKPHLVVEKPLVSPPP---------------------AELQSHMGTEVMVETADNFQEVLSLTESPVPQRTEKFGKKNRKRLDSRAEEGSVQAITEGKVKKDARTLSDFNSLISSPRLG-REKKKVKSQKDQL-KSKKLNKT-NEFQDSSESEPELFISGDELMNQSQG-SKKGWKSKRSLRTASELEEFKCRKASEKEDGRLGSQGFVYVMANKQPLWNEATQVYQLDFGGRVTQESAKNFQIELEGRQVMQFGRIDGNAYILDFQYPFSAVQAFAVALANVTQRLK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZFM2-1", "uniprot_id": "D3ZFM2_RAT", "id": "D3ZFM2-1", "name": "Tubby-related protein 4", "aln": "-------------MYAAVEHGPLLCSDSNILCLSWKGRVPKSEKEKP---VCRRRYYEEGWLATGNGRGVVGVTFTSSHCRRDRSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGILSMSWNYPIFLVEDSSESDTDSDDYSPPQDGPAAYPIPVQNIKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLK---EVVAQWCTQGDLLAVAGMEQQAQLSELPNGP---LLKSAMVKFYNVRGEHIFTLDTLVQRP-IISICWGHRDSRLLMASGPALYVVRVEHRVSSLQLLCQQAIASTLREDKDVNKLTLPPRLCSYLSTAFIPTIKPPIPDPNNMRDFVSYPSAGNERLHCTMKRTEDDPEVG-GPCYTLYLEYLGGLVPILKGRRISKLRPEFVIMDPRTDSKSDEIYGNNLISTVIDSCNCSDSSDIELSDDWAAKKSPKISRASKSPKLP------RISIEARKSPKLPRAAQEISRSPRLPMRKPSMGSPSLTRREFPFEDITQHNYLAQVTSNIWGTKFKIVGLAAFLPTNLGAVIYKTSLLHLQPRQMTIYLPEVRKISMDYINLPVFNPNVFSEDEDDLPVTGASGVPENNPPCTVNIPIAPIHSSAQALSPTQSIGLVQSLLANQNVQLDVLTNQTTAVGSVEHAGDAAT---------------------------QYPVSSRYSNPGQVIFGGVEMGRIIQ---NPPQLPLPPPPPPPPQGP---------------------------------------------------------------------------------------------------------------------------------------------------------IQLSAVDHGAR----------------DHEHLQKSAK----------------------------------------------------ALRPVP---------------------------------QLA-EGDAVVFSAPQEVQVAKMNPPPPYPGTIP---AAPTTAAPPPPLPPPQP----PVDVCLKKGDFSLYPTAAHYQPPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATE-KKVPQPCTSATLNRLTVPRYSIPTGDPPPYPEIASQLAQGRNATQRLDNSLIHATLRRNNREVALKMAQLADSSRAPLQPPAKPKGGTGGAVAQLPARPPPALYTCSQCSG------------------------------AGPSSQSGAALAHAISTSPLASQSSYNLLSPPDTSRDRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEATVTMKRPPPYQWDPVLGEDVWVPQERTAQPTVPNPLKLSPLMIGQGQHLDVARVPFVS--PKSPSSPTATFQTGYGMGV-PYPGSYNT--PSLPGVQAP---CSPKDALSPAQFAQQESAVVLQPAYP---PSLS---YCTLPPTYPGSSTCSSLQLPPIALHPWNSYSTCPPMQNTQGTLPSKPHLVVEKPLVSPPP---------------------AELQSHMGTEVMVETADNFQEVLSLTESPVPQRTEKFGKKNRKRLDSRAEEGSVQAITEGKVRKDARTLSDFNSLIASPRLG-REKKKVKSQKDQL-KSKKLNKT-NEFQDSSESEPELFISGDELMNQSQG-SKKGWKSKRSLRTASELEEFKGRKASEKEDGRLGSQGFVYVMANKQPLWNEATQVYQLDFGGRVTQESAKNFQIELEGRQVMQFGRIDGNAYILDFQYPFSAVQAFAVALANVTQRLK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NRJ4-1", "uniprot_id": "TULP4_HUMAN", "id": "Q9NRJ4-1", "name": "Tubby-related protein 4", "aln": "-------------MYAAVEHGPVLCSDSNILCLSWKGRVPKSEKEKP---VCRRRYYEEGWLATGNGRGVVGVTFTSSHCRRDRSTPQRINFNLRGHNSEVVLVRWNEPYQKLATCDADGGIFVWIQYEGRWSVELVNDRGAQVSDFTWSHDGTQALISYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGVLGMSWNYPIFLVEDSSESDTDSDDYAPPQDGPAAYPIPVQNIKPLLTVSFTSGDISLMNNYDDLSPTVIRSGLK---EVVAQWCTQGDLLAVAGMERQTQLGELPNGP---LLKSAMVKFYNVRGEHIFTLDTLVQRP-IISICWGHRDSRLLMASGPALYVVRVEHRVSSLQLLCQQAIASTLREDKDVSKLTLPPRLCSYLSTAFIPTIKPPIPDPNNMRDFVSYPSAGNERLHCTMKRTEDDPEVG-GPCYTLYLEYLGGLVPILKGRRISKLRPEFVIMDPRTDSKPDEIYGNSLISTVIDSCNCSDSSDIELSDDWAAKKSPKISRASKSPKLP------RISIEARKSPKLPRAAQELSRSPRLPLRKPSVGSPSLTRREFPFEDITQHNYLAQVTSNIWGTKFKIVGLAAFLPTNLGAVIYKTSLLHLQPRQMTIYLPEVRKISMDYINLPVFNPNVFSEDEDDLPVTGASGVPENSPPCTVNIPIAPIHSSAQAMSPTQSIGLVQSLLANQNVQLDVLTNQTTAVGTAEHAGDSAT---------------------------QYPVSNRYSNPGQVIFGSVEMGRIIQ---NPPPLSLPPPP----QGP---------------------------------------------------------------------------------------------------------------------------------------------------------MQLSTVGHGDR----------------DHEHLQKSAK----------------------------------------------------ALRPTP---------------------------------QLAAEGDAVVFSAPQEVQVTKINPPPPYPGTIP---AAPTTAAPPPPLPPPQP----PVDVCLKKGDFSLYPTSVHYQTPLGYERITTFDSSGNVEEVCRPRTRMLCSQNTYTLPGPGSSATLRLTATE-KKVPQPCSSATLNRLTVPRYSIPTGDPPPYPEIASQLAQGRGAAQRSDNSLIHATLRRNNREATLKMAQLADSPRAPLQPLAKSKGGPGGVVTQLPARPPPALYTCSQCSG------------------------------TGPSSQPGASLAHTASASPLASQSSYSLLSPPDSARDRTDYVNSAFTEDEALSQHCQLEKPLRHPPLPEAAVTLKRPPPYQWDPMLGEDVWVPQERTAQTSGPNPLKLSSLMLSQGQHLDVSRLPFIS--PKSPASPTATFQTGYGMGV-PYPGSYNN--PPLPGVQAP---CSPKDALSPTQFAQQEPAVVLQPLYP---PSLS---YCTLPPMYPGSSTCSSLQLPPVALHPWSSYSACPPMQNPQGTLPPKPHLVVEKPLVSPPP---------------------ADLQSHLGTEVMVETADNFQEVLSLTESPVPQRTEKFGKKNRKRLDSRAEEGSVQAITEGKVKKEARTLSDFNSLISSPHLG-REKKKVKSQKDQL-KSKKLNKT-NEFQDSSESEPELFISGDELMNQSQG-SRKGWKSKRSPRAAGELEEAKCRRASEKEDGRLGSQGFVYVMANKQPLWNEATQVYQLDFGGRVTQESAKNFQIELEGRQVMQFGRIDGSAYILDFQYPFSAVQAFAVALANVTQRLK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TB44-1", "uniprot_id": "A0AB32TB44_DANRE", "id": "A0AB32TB44-1", "name": "Tubby-related protein 4", "aln": "MSRDYEESGQSVGMLAAVEHGPVLCSDSNILCLSWKGRVPKSEKEKP---VCRRRYYEEGWLATGNARGVVGVTFTSSHCRRDRNTPQRINFNLRGHNSEVVLVRWNEPFQKLATCDMEGGIFVWIQYEGRWSVELVNDRGAQVSDFTWSHDGTQALIAYRDGFVLVGSVSGQRHWSSEINLESQITCGIWTPDDQQVLFGTADGQVIVMDCHGRMLAHVLLHESDGIVSMSWNCPNFLVEDSTESDTDSDDQTPAH---------VQNLKPLLTVSFISGDISLMNNYDDLSPNIIRSGLK---DVEVQWCSQGDLLAVAGMERHG----LPTDS---LMRNALVKFYNVQGEHIYTLETPAQRP-ITTICWGHRDSRLFLACGPALYVVRVEHRVASLQLLCQQGIASALKEERDVGKLNMPSLLCSYVTTAFIPTIKPPIPDPNNIRDFVSYPTAGNERLHCTMKRSEENPEAG-GPCYTLYLEHLGGLVPILKGRRISKLRPEFVIMDPKMDGKADEVCVNGMISYMTDSCNCSDSSDIELSDEWVGRKSPKLSRGNRSPKLPRYSKHIRINMESRKSPKLAQTSQEMSRSPRLPK-KPPLRSPSLTRREFPVDGFSEHNYLAQVTSNIWGTKFKIVGLASFLPANLGAVIYKTSLLHLQPRQMTIYLPEVRKISLDFMSLPVFNPNVFSEDEDDLPVMGPSGVSADNPSCTVNIPIAPIHSPAQAMSPTQSIGLVQSLLANQNIQLDVLTNPTATAAAATAAAAAAAAAATAAAATAAAANATVSEHSQDTVTAQYTVPTRYSNPGQVIFSGLEMNNILSGTLPPPPHHLPQPPHQQRQQPQDHQQSKHQQQLQPQQHHLKLQHQPQQLHQQSLQQQHMQHQQQLQTPQHQQLQQQHQQQLQQQHQLQQQHQQQLQQQHQQQLQQQHQQQQLQQQHQQQQLQQQHQQQLQLQQQHQQLQQQHQQHQQLQQQHQQLQQQHQQQLQQHQQQLHQQQMQQHQLQHQQQQIHQQQFQQQQQQLQIQHEQMQQQQQQMQQQQQQIRQQILEMRQQQQQLQQQHQQIQMQHQQMQRQHQQMQQQLKMQMSLQPSPSGYATLSLHHLQLMPQIPHPDQPPDRGEQVLPLKVPSRPQSFIEMDTLEIQLRKVNPPPPYPGTVVSAAAAIPTTAPPGLLVSNENGTTLSTDTCLTKDEFSLHPISLQYPTPLGYERITTFDSSGNVEEVCRPRRRLLRNQNAYGMQGMGSSATLKVTSSENKKVQLPYSSATLSRLSVPRYSIPSGDPPPYPDTSNQMNTIRSPTQRIDSSLIHATLRRDRREPSLKVSQMVDAVRT-LPTKSKMNG---SLTLSYQPRIPSALYTCTQCSSNSSSTSVSVTGGGTNSSGIAGGTVVRQDFPPGKGAQHSTIIVHSKSASPLASQSSYNLLSPTDNSRDRTVYVNSAFTEDETVSQQCHLEKSMRHLTLGDVNLTVKRPPPYQWDSPAAEQLWIPQEQNLLP-GPPPHKPPPFILSQPQHLEIARLPFVLSAKHTPSPNSMTLPSPYQLSLSPYPSVVGHGGPPLQPLQSPAQTCGPNDMVASSPFSQPDSTLVLPPGYP---SNVSNLGCCTLPPMYPGTSSCNNLQLHPMSLHPWSTYSTCPPMPDHSATLPSKTHQTLEKPVLSPPPPPPPPPPPPPPPPLPPPPPPVEHLNLQSTSEVVAESGESFQDQSSLNES--PQGAERFSKKGRKRLDSRAEEANMSGVSEGKSKKESRTLSDFNSLISSPRLGSREKKKPKGQKEPLNKTKKLSRTSNEFQDSSESEPELFISGDELMNQSQS-SKKGWKSKRNLRTANELEEIKCRKANEREDRSLGSQGFVYVMANKQPLWNEATQVYQLDFGGRVTQESAKNFQIELDGRQVMQFGRIDGNAYILDFQYPFSAVQAFAVALANVTQRLK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KI44-1", "uniprot_id": "A0A0B4KI44_DROME", "id": "A0A0B4KI44-1", "name": "", "aln": "-------------MHLHFERNINTKCDCTILSLSWMGKVPDDIPEDEGWKLNRTNYYQEGWLATGNVRGIVGVTFTTSHCRKNMDYPLRTNYNLRGHRSDVILVKWNEPYQKLASCDSSGIIFVWIKYEGRWSIELINDRNTPVTHFSWSHDGRMALICYQDGFVLVGSVAGQRYWSSMLNLESTITCGIWTPDDQQVYFGTTQGQVIVMDVHGAMVSQVQLSNDVPITSMAWSCEKFKMEEGEEAEPGVTN--------------AAKRSFVLAVSFQNGYIYLLKSFDDVSPAHINTCLNGALGMVMEWSNSRELLAVAGTLRTGVDGTKTEDMGTPSCYTNLVKFYTETGTCLYQAHIPCSSATVSAITWGHNDKRLFIATGTQVHIAWVSRRVASLQLLCRLEIQASVGSESLLPLLPLPSRIKSLIGNLFAQTIRCCVPDLKSLRDFVSRPPLCSTRLHCTMIRHDDDSNLSSGTCYTLYLEYLGGLVPLLKGKRTSKIRPEFVIFDPQVNDSPLYFQYSAEAKSSSGSSQSTTTGNSGRTDSSDSDFEERSRFG--SPRTP------------RKKRVRPKRRHQAGDRLSASGGGVSNDPDSLDELAYVDTLPEQEVKLVEVTSNIWGTKFKIHGLAKTVPANLGQVTYKTSLLHLQPRQMTLVITELR-DDFPPGPDPSFNPNIFSEDEDEHHQHQGIHHDAVPQVNVITAQDGASLKPPIIPQRRLTDGASAPLIAPMSPRPNRILARHKNSLTVNGERGSGS------------------------------------SAGLSPLARAES-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDDDSSNESQE-----------------------------------------------------------------------------------------------AGAAGSQSTTVLLHQAPSNGSGPGP-------SCSKSITRPKTISSFKN----------------SYSRSSSNSSCQSRHAISPLYCDGAVPTLQSPKNAVAPSDIIFERPAVPAAGQTTLMSYS------SNADYANNVVQVKNALMSEPVRSANSHVNPVPLNLNLNLERMDARVKCTAPTTSSTAKRREMLYIDEETQSPTPTPSSSSMKRTPTVVSIAPALPDSITRSCSVGY----------------------------------LDSVAITPSDEALSALRKDAPNKRLILVDKKRNRRKRQ----QQEDARRHKLQQTGKSKSLDSCDLLSLQTKLSSKEHEQVVRKLQEISDSSACSSAANTLCFKCRNNMSPSSACKRCQPSASSVLDEITAVVPAVEPAKESPAVQAKPAPKKR--------------FDVITSFTDSPLFTRKHRFGIGRSKETAGT--------ENSTPLLGRKQDNGFSFVKQLSEVRWRRKEQPAQAQVNGSSNASTLERQPQPEITGAACG---------------------TVEATPVEAKASVSLHTQALTTLENIISRLRDLDEGRLTPPSTPQRLPRSSPASPAASKKNKRQQSNSPIRHILNSPLLNRRQRKKQ-----------------SIIESSDDEGNQTNGSGEESNNAGNGKQYRDLETFQKAQLRQKLKRGKIEPNGSASCANPAPVRREFVMHNKAPMWNEMSQVYQLDFGGRVTQESAKNFQIEFRGKQVMQFGRIDGNAYTLDFQYPFSALQAFAVALANVTQRLK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .*:. .*..**.*** *:**.. *. : * .**:******** **:******:****:: . * * *:*****.*:*:**:****:****:** .* *****:******:**:***.: *:.*:***** ***.*:*********:***:*** :**** ************* ***::******* ** *:::* * :. : .*:*. * :*:. *::.. : . : . :*:*** .* * *::.:**:** *.: *: : :*... :****** : . . . :****. * :: . . . : :* ***.*.**::* *. :::. *.:**:******: * ::: .: : * :*. : * : . * **: :** :.:***** *. . ****** * :::.: . *.*******:******:***:* **:******:**: :... . . . .*.:.: :.: :*. . . : . **: * **. .: :: . . . . ** . : :. *.:************ *** :*:*** * **************: :.*:* .: * ****:******: .:. .. ... . : * .*:* . : : : :. :.: ..* :. * :.: ::. : : . :: * . * * :. : : * : . : :. : . . . *:.: ..* * : *: : .: : . ::. : : . . :. : . : * . :. .. .. . :* * : :: . :: : : :: . :. . . . . * :: . . . : : : *.* .::. . * *. *:* :::: :: : : : .: .. : : : :.:. . :. . . .: . . .: . . : .: . *. . .: : : . . : . .. * . ....: . . *. : ..: ... :* :: .. *. .. . * :* : .: .* ... . : .* .* :: * :. :: ** *. *::** . ::.*.:. : **:* * .:. . :. :: :. : :*:. * . .. . .. :** ** *:*** :**********************: *:**********.** *********:***************", "identical_positions": 401, "similar_positions": 430, "identity": "20.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-709", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MA92-1", "uniprot_id": "F1MA92_RAT", "id": "F1MA92-1", "name": "", "aln": "MEIRQHEWLSASPHEGFEQMRLKSRPKEPSPSLTRVGANFYSSVKQQDYSASVWLRRKDKLEHSQQKCIVIFALVCCFAVLVALIFSAVDIMGEDEDGLSEKNCQN--KCRIALVENIPEGLNYS--EDAPFHLPLFQGWMNLLNMAKKSVDIVSSHWDLNHTHP------SACQGQRLFEKLLQLTSQN-----IEVKLVSDVTADSKVLEALKLKG----AEVTYMNMTAYN-KGRLQSSFWIVDKQHVYIGSAGLDWRSLGQMKELGVIFYNCSCLVLDLQRIFALYSSLKFKSRVPQT-WSKRLYGVYDNEKKLQLQLN-ETKSQAFVSNSPKLFCPKNRSFDIDAIYSVIDDAKQYVYIAVTDYLPISSTSTKR----TYWPDLDGKIREALVLRSVKVRLLISFWKETDPLTFNFISSLKAICTEIANCSLKVKFFDLERENACATKEQKNQTFPKLNRNKYMVTDGAAYIGNFDWVGNDFTQNAGTGLVINQADVR-DNR-SIIKQLKDVFERDWYSPYAKSIQP-TKQPNCSNLSKLKTPSNQPAIYNTTGREPLSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UNN8-1", "uniprot_id": "PLD5_MOUSE", "id": "Q3UNN8-1", "name": "Inactive phospholipase D5", "aln": "MEIRQHEWLSASPHEGFEQMRLKSRPKEPSPSLTRVGANFYSSVKQQDYSASVWLRRKDKLEHSQQKCIVIFALVCCFAVLVALIFSAVDIMGEDEDGLSEKNCQN--KCRIALVENIPEGLNYS--EDAPFHLPLFQGWMNLLNMAKKSVDIVSSHWDLNHTHP------AACQGQRLFEKLLQLTSQN-----IEVKLVSDVTADSKVLEALKLKG----AEVTYMNMTAYN-KGRLQSSFWIVDKQHVYIGSAGLDWRSLGQMKELGVIFYNCSCLVLDLQRIFALYSSLKFKSRVPQT-WSKRLYGVYDNEKKLQLQLN-ETKSQAFVSNSPKLFCPKNRSFDIDAIYSVIDDAKQYVYIAVTDYLPISSTSSKR----TYWPDLDGKIREALVLRSVKVRLLISFWKETDPLTFNFISSLKAICTEIANCSLKVKFFDLERENACATKEQKNQTFPKLNRNKYMVTDGAAYIGNFDWVGNDFTQNAGTGLVINQADVR-DNR-SIIKQLKDVFERDWYSPYAKSIQP-TKQPNCSSLSKLKSPSKQPAMANATGREPLSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N7P1-1", "uniprot_id": "PLD5_HUMAN", "id": "Q8N7P1-1", "name": "Inactive phospholipase D5", "aln": "MEIRQHEWLSASPHEGFEQMRLKSRPKEPSPSLTRVGANFYSSVKQQDYSASVWLRRKDKLEHSQQKCIVIFALVCCFAILVALIFSAVDIMGEDEDGLSEKNCQN--KCRIALVENIPEGLNYS--ENAPFHLSLFQGWMNLLNMAKKSVDIVSSHWDLNHTHP------SACQGQRLFEKLLQLTSQN-----IEIKLVSDVTADSKVLEALKLKG----AEVTYMNMTAYN-KGRLQSSFWIVDKQHVYIGSAGLDWQSLGQMKELGVIFYNCSCLVLDLQRIFALYSSLKFKSRVPQT-WSKRLYGVYDNEKKLQLQLN-ETKSQAFVSNSPKLFCPKNRSFDIDAIYSVIDDAKQYVYIAVMDYLPISSTSTKR----TYWPDLDAKIREALVLRSVRVRLLLSFWKETDPLTFNFISSLKAICTEIANCSLKVKFFDLERENACATKEQKNHTFPRLNRNKYMVTDGAAYIGNFDWVGNDFTQNAGTGLVINQADVR-NNR-SIIKQLKDVFERDWYSPYAKTLQP-TKQPNCSSLFKLKPLSNKTATDDTGGKDPRNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TLP8-1", "uniprot_id": "A0AB32TLP8_DANRE", "id": "A0AB32TLP8-1", "name": "", "aln": "--MQDRRFVSEAP-----GLRLTPDLGLFSAPLARPGNSMFSGAQQQDYSAMIWLKRRDKLERSQQKCIAVFALVCCFAVLVALIFSAVDVWGEDEDGVTEENCSR--NCRIVLVENIPGELSFN--SSS--HLPLTVGLNHLLDQAKLSVEIVSPYWALTSTDQG-ARVYTSYQGQYLFQRLLSLKSRG-----VKLKVVSDQ-PNSTELKSMADRY----AEVRYVNMTALT-RGRLLSSFWVVDRKHIYIGSAGMNWKALSKLKELGIIVYDCSCLAMDLHRIFSFYWQLQYRDYIPSI-WSKRVTAVYSRDEPLQLTLN-NTDASAYVSTSPELFCPKGRSRDIDAIRHVIREAKRYIYISVTDYLPLVNRSFRGSAIIRYWSPIDEMLREAAVLKEVKVRLLISLWTRTHPLTFNFMTSMQALCTGLPVCSIEVRFYRG--------KEQMGGFQHRMNENKFVVTDNAVYIGNLDWVGSEFAFNAGAGLVFQEPENQQDGRDSIVEQLTAAFERDWFSPYTISLLSGSTTLQESQHGKQKLQSLKTKTESREHE-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIF2-1", "uniprot_id": "Q9VIF2_DROME", "id": "Q9VIF2-1", "name": "", "aln": "--MPEYKKLEDQESDVENANRTTVQNTATVQDAG---------EGQRQAAG-------------QQAGQMVTVSLFMLLFLGSSYFQPRPRLHQYKGGRGHGLLEK-FDCNIQLVESIPIGLTYP--DGSPRFLSTYEAWLELLESATTSLDIASFYWTLKAEDTPGVSDNSTRPGEDVFARLLANGNGGSRSPRIKIRIAQSEPSSGTPNLNTKLLASAGAAEVVSISFPKYFGSGVLHTKLWVVDNKHFYLGSANMDWRALTQVKEMGVLVQNCPELTHDVAKIFGEYWYLGNSESSRIPDWDWRYATSYNLKHPMQLSVNKNTSIEGFLSSSPPPLSPSGRTDDLNAILNTINTAITYVNIAVMDYYPLIIYEKNH----HYWPFIDDALRKAAVERGVAVKLLISWWKHSNPSEDRYLRSLQDLASKEDKIDIQIRRFIVP-----TDSSQEKIPFGRVNHNKYMVTDRVAYIGTSNWSGDYFTDTAGIGLVLSETFETETTN-TLRSDLRNVFERDWNSKYATPLV----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VIE9-1", "uniprot_id": "Q9VIE9_DROME", "id": "Q9VIE9-1", "name": "PLD phosphodiesterase domain-containing protein", "aln": "--MSERRVVHEIPGEYQPVPRAPEEPTPLTTSCCRRPNCGLGLQDERNICS-------------CKHGYIIPVLILFVLVM-IVLLLPWETYHRNENGNSPVPVEKPLPCQLELVESLPLGLNYSQWQSHPQLSSTFDAWQLLLGRAKASLDIVSPHWTLRGLD---VNDSSTGPGDQLFQQLLSNGDAG--RPKLRVRIVVNRSHDSLWHADARILANYGAADVVGINF--------LHSKLWLVDGEHFYLGTASMDWRSLTQRKELGVLARNCPHLALDLGKIFKAYWYLGSNEVPKS--WPWIYHTHINQRRPLLLNINKKHTMRAYLSTSPPELIATGRTRELDAILEAIDKATDVIYLSLMEYSPRLRRSNKL----EYWPVIDNALRRAALERGVAIKVLISWWKYSDPSEDHFLRSLQALDKITEGVDIQMRRFVVP-----TTNELERISGGRVNCNSYLVTDRVAFIGTSSFSGEHFTYSAGIGLVLQD--MEYNNN-SLRTDLMAIFLRDWFSPYALPLKPILRI-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : * ::: .. : : . : . .: : . . :.* .. *.: ***.:* *.: .. . . ** *. *::*.* :* * . :: *: :* :** . . :.:::. . .. *:* :.: * :.:*:** :*.*:*:*.::*::* : **:*:: :*. *. *: :** * * . * . . : * :* : .::*.** : ...*: :::** .* * : ::: :* * . . **. :* :*.* : : * :::*:* *. :.* .:: *:: : . .:::: : .. ::* *.::*** ..:**. .: *. *: .** ***:.: . :: :* * *** * *: .: ", "identical_positions": 87, "similar_positions": 159, "identity": "15.4%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-710", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9QAT4-1", "uniprot_id": "SC16A_MOUSE", "id": "E9QAT4-1", "name": "Protein transport protein Sec16A", "aln": "MQPPPQAVPSGVAGPPPAGNPRSMFWANSPYRKPANN-APVAPITRPLQPVTDPFAFNRQTLQNTPVGSSSKSSLPNLPGPALSVFSQWPGLPVTPTNAGDSSTGLHEPLSGTLSQPRADASLFPPASTPSSLPGLEVSRNAEADPSSGHEVQMLPHSAHYIPGVGPEQPLGGQMNDSGSGPDQPMNRHAPHDGAVTHAASPFLPQP--QMPGQWGPAQGGPQPSYQ-HHSPYLEGPVQNMGLQAASLPHFPPPSSLHQGPGHESHAPQTFTPASLASGEGNEIVHQQSKNHPLSSFPPKHTFEQNSRIGNMWASPELKQNPGVNKEHLLDPAHVNPFTQGNSPENQAHHPPVAATN-----HALQEAASGALSMFFQGEETENEENLSSEKAGLDKRLNLDSFSSTSRLGHPPPPGASGVYQAFPRGPSSEAAQEGDAQPYFSQSVGVRLDKQSTVPPANDAWGDVPGTGTRCASGPQCENVENLEFVQNQEVLPRETLSVDPFPLSDQIRYGPLPGPAASRPATVGLTRGGGLNLEAPDTPLHPTRPDSVSSSYSSHSHRSPPGS------ARPQELVGTFIQQEVGKLEDD-----TSGSFFKQIDSSPVGGETDEVTGSQNCCSSLSQPSTPSPPKPTGVFQTSANSSFEPVKSHLVGVKPVEADRANMVVEVRGTQYCPKKRRAAVAPPDATSGNLEQPPDNMETPCAPQACPLPLSTTGEAGQLVSNTAGTPLDTVRPVPDKRPSARAQGPVK-CESPATTLWAQNELPDFGGNVLLAPAAPALYVPVKP-KPSEVVHHPEKGMSGQKAWKQGSVPPLQNQDPPGASENLENPPKVGEEEALPVQASSGYASLLSSPPTESLHNQPVLIAQPDQSYNLAQPINFSVSLLNPNEKNQSWGDAVVGERSIVSNNWALGGDPEERAALSGVPASAVTGASLPSSIPQNCAPQGSGSSEMIASQSASWLVQQLSPQTPQSPHPNAEKGPSE------FVSSPAGNTSVMLVPPASSTLVPNSNKAKHSSNQEEAVGALDFTLNRTLENPVRMYSPSPSDGPASQQPLPNHPRQSGPGLHNQDHFYQQVTKDAQ--DQHRLERAQPELVPPRPQNSPQ-VPQASCPEPSNPESPPTQGQSESLAQP---PASPASVNTGQLL-PQPPQASSASVTSTNSSQAAVRSEQLWLHPPPPNTFGPAPQDLASYYYYRPLYDAYQSQYPSPYPSDPGTASLYYQDMYGLYEPRYRPYDSSASAYAENHRYSEPERPSSRASHYSDQLAPRQGYPEGYYNSKSGWSSHSDYYANYYSGQYD-YGDPSRWDRY-YGSRLRDPRTWDRRYWYDSEHDPYRKDHYAYSDRPEKC-----DDHWRYDPRFTGSFDDDAEIHRDPYGEEADRRSIHSEHSARSLRSTHSLPSRRSSLSSHSHQSQIYRSH-HVTGGSFEAPHAPGSFHGDYAYGTYASNFSGAHGFPEYSYPADTSWPAVEQVPSRPTSPEKFTVPHVCARFGPGGQLLKVIPNLPSEGQPALVEIHSLETLLQHTPEQEEMRSFPGPLGKDDTHKVDVINFAQN--------------KATKCLQNESLIDKESASLLWKFIILLCRQNGTVVGTDIAELLLRDHR------TVWLPGKSPNEANLIDFTNEAVEQVEEEESGEAQLSFLTDS-----------------QTVTTSVLEKETERFRELLLYGRKKDALESAMKNGLWGHALLLASKMDSRTHARVMTRFAN-SLPINDPLQTVYQLMSGRMPAASTCCGDEKWGDWRPHLAMVLSNLNNNMDVESRTMATMGDTLASKGLLDAAHFCYLMAQVGFG----------VYTKKTTKLVLIGSNHSLPFLKFATNEAIQRTEAYEYAQSLGAHTCSLPNFQVFKFIYLCRLAEMGLATQAFHYCEVIAKSVLTQPGAYSPVLISQLTQMASQLRLFDPQLKEKP-----------EEESFVEPAWLVQLQHVERQIQEGTVLWSQDGTEPQQ---------------------CRITSGSEVE---QSDGPGLNQQAGPQADNPLLMPSTEPLMHG---VQLLPTAPQTLPDGQP-------------------AHLSRVPMFPVPMSRGPLELSPAYGPPG-SALGFPESSRSDPAVLHPGQALPPTTLSLQESGLPPQEAK---------------------SPDPEMVPRGSPVRHSPPELSQEEFGESFADPGS-------------------SRTAQDLETSPVWDLGSSSLTRAP-SLTSDSEGKKPAQAVKKEPKEPKKTES--WFSRWLPGKKRTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSFPRVPQVAP----TGPAGPP-----TASVNVFSRKAGGSRARYVDVLNPS---------------------------GTQRSEPALAPADFFAPLAPLPIPSN-------------------------------LFVPNPDAEEPQPADGTGCRGQAPAG--------------------------------TQSKAESTLEPKVGSSTVSAPGPELLPSKP-DGSQGG--------------------EAPGDHCPTGAPHGGSVPFYNPAQLVQASVTSGNSRPGRIGQRKYAALN---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZTA3-1", "uniprot_id": "A0A8I5ZTA3_RAT", "id": "A0A8I5ZTA3-1", "name": "Protein transport protein sec16", "aln": "MQPPPQAVPSGVAGPPPAGNPRSSFWANSPYRKPANNNAPVAPITRPLQPVTDPFAFNRQTLQNTPVGSSSKSSPPNLPGPALPVFSQWPGLPVPPTNAGDSSTGLHEPLPGTLSQPRADPSLFPPASTPSSLPGLEVNRSAEVDSSSGPEVQMLPHPPHYIPGVGPEQPHGGHLNDSGAGPDQSMNRHAPHDGAVAHAASPFFPQP--QMPGQWGPVHGGPPPSYH-HHSPCLEGPVQDMGPQAASLPHFPSPSSLHEGPGHESRVPQTFTPASLASGEGNEIVHQQSKNYPSSSFPPKHSFEQNSRVGNMWASAEFRQNPGVNKEHLLDPAHVNPFTQGNSPENQVHHPPVAATN-----HALQEAASGALSMFFQGEETENEENLSSEKAGLDDRLDSGSFSSTSRLGHPPLPGAGGVYQ---------AAQEGDVQPYFSQFVGIRHDKQTTMTPANDAWGDIPGAGTHCASGPQCENVENLEFVQNQEVLPRETVNVDPFSPSDQFRYGPLPGPAASRPVTSGLTRGGGLNLEAPDMPLHPTRPDSVSSSYSNHSHRSPPGS------ARPQELVGTFIQQEVGKLEDD-----TSGSFFKQIDSSPVGGETDEMTRSQNYCSSLSQPSTPSPPKPTGVFQTSANSSFEPVKSHLVGVKPVEADRANMVVEVRGTQNCQKHG-AAVLPPDATPGNLEQPPDNMETLCAPQACPLPLSTTGEAGQLVSHTAGPPLDTVRPMPDKRSSARAQGPVK-CESPATTLWAQNELPDFGGNVLLAPAAPALYVPVKP-KPSEVVHHPEKGMSGQQSWKSGSVPPLQNQDPPGASENLENPPKVGEEEALPLQASSGYASLLSSPPTESLHNQPVLIAQPDQSYNLAQPINFSVSLPNPNEKNQCWGDAVVGEKSMVS-TRALGADHEEHAALSAIPASTVTGSSLPNSVTQNCAPRGSGSSEMIASQPASWLVQQLSPQIPQSQHPNAEKGPSE------FVNSPA-NGSVMLAPPANSAVIPNSNKGYHSRNPEEAIGALDFTLSRTLENPVRMCSPSHSNSPASQQPLANHPRQSGPGLHNQDHFYQQVTKDAQ--DHRSLERGQSELVPPPPQNSPQQVPQAACPEPSNPESPPTQGQSEGLVQP---SASPAPVNTGQQ--PQPPQSSSASVTSTNSNQAAVRSEQPWLHPPP-TTFGPAPQDLASYYYYRPPYEAYQSPYPSPYPSDPGAASLYYQDIYGLYEPRYRPYDSSASAYAENHRYSEPERPSSRASHYSDQLTPRQGYPEGYYNSKSGWSSHSDYYANYYSGQYD-YGDPGRWDRY-YGSRFRDPRTWDRRYWYDSDHDPYRKDNYAYSDRPEKC-----DDHWRYDPRFTGSFDDDTELHRDPYGEEVDRRSIHSEHSARSLRSTHSLPSRRSSLSSHSHQSQIYRSH-HVTGGSFEAPHAPGSFHGDYAYGTYASNFSGAHGFPEYSYPADTSWPAAEQVPSRPTSPEKFTVPHVCARFGPGGQLLKVIPNLPSEGQPALVEIHSLETLLQHTPEQEEMRSFPGPLGKDDTHKVDVINFAQN--------------KATKCLQNESLIDKESASLLWNFIILLCRQNGTVVGTDIAELLLRDHR------TVWLPGKSPNEANLIDFTNEAVEQVEEEESGEAQLSFLTDS-----------------QTVTSSVLEKETERFRELLLYGRKKDALESAMKNGLWGHALLLASKMDSRTHARVMTRFAN-SLPINDPLQTVYQLMSGRMPAASTCCGDEKWGDWRPHLAMVLSNLNNNMDVESRTMATMGDTLASKGLLDAAHFCYLMAQVGFG----------VYTKKTTKLVLIGSNHSLPFLKFATNEAIQRTEAYEYAQSLGAHTCSLPNFQVFKFIYLCRLAEMGLATQAFHYCEVIAKSVLTQPTAYSPVLISQLIQMASQLRLFDPQLKEKP-----------EEESFVEPAWLVQLQHVERQIQEGTVLWNQDGTEPQQ---------------------CHITSGSEVE---QPDGPGLNQQAGPRADNPLLMPSTEPLVHS---VQLLPTAPQTLPDGQP-------------------AHLARVPMFPVPMSRPPLELSAAYGPPG-SVLGFPESSRSDPAVLHPGQALPPATPGLQESGPPLQEAR---------------------SPDPEMVPQGSPVRHSPPEPREEEFGKNVADLGS-------------------SRTAQDSETSPVWDLGSSSLTRAP-SLTPDSEGKKPAQAVKKEPKEPKKTES--WFSRWLPGKKRTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSFPRVPQAAP----TGPAGPP-----MASVNVFSRKAGGSRARYVDVLNPS---------------------------GTQRSEPALAPADFFAPLAPLPIPSN-------------------------------LFVPNPDAEESQPADGTGCRGQAPAG--------------------------------TQSKAEPTLEAKVVSSTVSAPGPELSPSKPADGSQGGELSRCSSLSSLSQEVSRHFHQAPGDHCPAGATPGGSVPFYNPAQLVQASVTSGTSRPGRIGQRKYAALN---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O15027-1", "uniprot_id": "SC16A_HUMAN", "id": "O15027-1", "name": "Protein transport protein Sec16A", "aln": "MQPPPQTVPSGMAGPPPAGNPRSVFWASSPYRRRANNNAAVAPTTCPLQPVTDPFAFSRQALQSTPLGSSSKSSPPVLQGPAPAGFSQHPGLLVPHTHARDSSQGPCEPLPGPLTQPRAHASPFSGALTPSAPPGPEMNRSAEVGPSSEPEVQTLPYLPHYIPGVDPETSHGGHPHGNMPGLDRPLSRQNPHDGVVTPAASPSLPQPGLQMPGQWGPVQGGPQPSGQ-HRSPCPEGPVPSGVPCATSVPHFPTPSILHQGPGHEQHSPLVAPPAALPSDGRDEVSHLQSGSHLANNSDPESTFRQNPRIVNHWASPELRQNPGVKNEHRPASALVNPLARGDSPENRTHHPLGAGAGSGCAPLEADSGASGALAMFFQGGETENEENLSSEKAGLSGQADFDDFCSSPGLGRPPAP-----------------THVGAGSLCQALLPGPSNE------AAGDVWGDTASTGVPDASGSQYENVENLEFVQNQEVLPSEPLNLDPSSPSDQFRYGPLPGPAVPRHGAVCHTG-------APDATLHTVHPDSVSSSYSSRSHGRLSGS------ARPQELVGTFIQQEVGKPEDE-----ASGSFFKQIDSSPVGGETDETTVSQNYRGSVSQPSTPSPPKPTGIFQTSANSSFEPVKSHLVGVKPFEADRANVVGEVRETCVRQKQCRPAAALPDASPGNLEQPPDNMETLCAPQVCPLPLNSTTEAVHMLPHAGAPPLDTVYPAPEKRPSARTQGPVK-CESPATTLWAQSELPDFGGNVLLAPAAPALYVCAKP-QPP-VVQPPEEAMSGQQSRNPSSAAPVQSRGGIGASENLENPPKMGEEEALQSQASSGYASLLSSPPTESLQNPPVLIAQPDHSYNLAQPINFSVSLSNSHEKNQSWREALVGDRPAVS-SWALGGDSGENTSLSGIPTSSVLSLSLPSSVAQSNFPQGSGASEMVSNQPANLLVQPPSQPVPENLVPESQKDRKAGSALPGFANSPAGSTSVVLVPPAHGTLVPDGNKANHSSHQEDTYGALDFTLSRTLENPVNVYNPSHSDSLASQQSVASHPRQSGPGAPNLDRFYQQVTKDAQ--GQPGLERAQQELVPPQQQASPPQLPKAMFSELSNPESLPAQGQAQNSAQS---PASLVLVDAGQQLPPRPPQSSSVSLVSSGSGQAAVPSEQPWPQPVPALAPGPPPQDLAAYYYYRPLYDAYQPQYSLPYPPEPGAASLYYQDVYSLYEPRYRPYDGAASAYAQNYRYPEPERPSSRASHSSERPPPRQGYPEGYYSSKSGWSSQSDYYASYYSSQYD-YGDPGHWDRYHYSARVRDPRTYDRRYWCDAEYDAYRREHSAFGDRPEKR-----DNNWRYDPRFTGSFDDDPDPHRDPYGEEVDRRSVHSEHSARSLHSAHSLASRRSSLSSHSHQSQIYRSH-NVAAGSYEAPLPPGSFHGDFAYGTYRSNFSSGPGFPEYGYPADTVWPAMEQVSSRPTSPEKFSVPHVCARFGPGGQLIKVIPNLPSEGQPALVEVHSMEALLQHTSEQEEMRAFPGPLAKDDTHKVDVINFAQN--------------KAMKCLQNENLIDKESASLLWNFIVLLCRQNGTVVGTDIAELLLRDHR------TVWLPGKSPNEANLIDFTNEAVEQVEEEESGEAQLSFLTGG-----------------PAAAASSLERETERFRELLLYGRKKDALESAMKNGLWGHALLLASKMDSRTHARVMTRFAN-SLPINDPLQTVYQLMSGRMPAASTCCGDEKWGDWRPHLAMVLSNLNNNMDVESRTMATMGDTLASRGLLDAAHFCYLMAQAGFG----------VYTKKTTKLVLIGSNHSLPFLKFATNEAIQRTEAYEYAQSLGAETCPLPSFQVFKFIYSCRLAEMGLATQAFHYCEAIAKSILTQPHLYSPVLISQLVQMASQLRLFDPQLKEKP-----------EEESLAAPTWLVHLQQVERQIKEGAGVWHQDGALPQQ---------------------CPGTPSSEME---QLDRPGLSQPGALGIANPLLAVPAPSPEHSSPSVRLLPSAPQTLPDGPL-------------------ASPARVPMFPVPLPPGPLEPGPGCVTPG-PALGFLEPS---------GPGLPPGVPPLQERRHLLQEAR---------------------SPDPGIVPQEAPVGNSLSELSEENFDGKFANLTP-------------------SRTVPDSEAPPGWDRADSGPTQPPLSLSPAPETKRPGQAAKKETKEPKKGES--WFFRWLPGKKKTEAYLPDDKNKSIVWDEKKNQWVNLNEPEEEKKAPPPPPTSMPKTVQAAP----PALPGPP-----GAPVNMYSRRAAGTRARYVDVLNPS---------------------------GTQRSEPALAPADFVAPLAPLPIPSN-------------------------------LFVPTPDAEEPQLPDGTGREGPAAAR--------------------------------GLANPEPAPEPKVLSSAASLPGSELPSSRP-EGSQGGELSRCSSMSSLSREVSQHFNQAPGDLPAAGGPPSGAMPFYNPAQLAQACATSGSSRLGRIGQRKHLVLN---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B225-1", "uniprot_id": "A0A8M3B225_DANRE", "id": "A0A8M3B225-1", "name": "Protein transport protein sec16", "aln": "MQPPPRTTPPGASGPPPPSGGPNSFRRNRPHKHGAAS--AMTPAAPSTMPVTDPFAFGRQNFSSMAGSSQ---APPTNSNPLPMQSPPLPGFNPTAPPQGPP------PGPAQAASPGPPPRIFTPQPVPSRPGSSSIPPPAEAGYFSSQ--EPIPYIAQLPNPAPPLIPSTSHPPSTTPTPP-------------VQSQAPFHSQPTPPLPSHWVPEHGSRPPSVQNYFQPTSDLPSQPFQAQAP----HPGPSPLTAPPPVPSPLTAPPPLTSPLTAPPLTQSQNQFQSAQPNVSGPAATYQQNS----HFPAHNYFSQSGGPSEPWFN-------QNPQDPSQRAYHVPYSEVP----------SDSGTLSMFFGGNDVENEETLTGE--GRVNGIHQPLHSTTEFSG-----------------------------------------------------PYLNDSGNIRAGTGPSDSVENLECVPNQEVLPSEPP------PSHAFEGGPN--------------------LETPDSAPRLARSASVSSSYSNVSHSSGHGAHSGGHVPRRQQVVGTFIQQESPRPPDHPPLHPSTGGYFEQIDSNPAAEASPTFP-------------TPSPPKPVGVFQASANSSFEPVRSHGVGVRPAEVDRARVVMEKGG--------------RDMQPGNLEHPPDNLETIYLS--------------------------------ERRPSSRAQGARRPIESPATALWAQNDTASLSANILLAPAAPSLTATFVPAHPSEVIQPPEDGPLDLHPARPDPQPP---------SENLEIPPDS------TPQASLGYASLLVTSPPEEALNQPVLIAPPSSNYSLIS----SQNLLQPS---------------------ILPSPQETAAPVHPHPQSSLTNQMPQNSPPTNQPPLLFSQTPVNFSSSSAQGVLNLTREANDGQAARPN-----------LSRAQSLKGDSQFLPPS-ATQAPPSSAASTNHNQPSNYQLLDFSMHQ----------PQSTNQVTSVPAVSQSTHPAG-LVNNTPGFYLQVTKDAQQGGQSDTDSLSHQQNSNPPLPSSNQLDNNQTLN-SHPPPPPAQNQPPPQAPPTH-PGAPPTGPGSAQPPPYPPQSGNSTTQPPQEPQRPPSSLGSQSGYGVPPAMPPGPGYPGYYPGAYPEYQDGRVPYPPQYPVDPRTQNYYQDDPYRRGDPRYGWYDGQNPGYREAER--QPERPSSRTSQYSDRPSSRQGYQEDFS--RSSRSAYDEYYANYYKRQYDAYGDRSRWYDPNAAYDPRYKAYYDQMYGWYYNQDGYRGGQAYYNQQYQNRGREGYDDPWRYYPGYDSSFDDDSR-RRDPYADDFDRRSVHSEQSAHSVHSSH---SRRSSFSSRSQQSQVYRSQPDLVSAAYDATG--TTLPADYTYSQYPNPSDTVNYGQDPYNSADNTWSAPEQPPPRPLTPEKFSIPHRCARFGPAGQLILVQPNLPSAGQPTLVEIHSMETLLQDSPEQSDMRSFPGPLVKEETHKVDVMKFAQN--------------KAQECLRNDDLIDKDSAYLIWEFIVLLCRQNGTVVGTDIADLLLKEHR------SVWLPGKSPNEANLIDFNNEAIEHAEEDMG---QMSLLSDT-----------------FMGVPENIGKDTERFRELLLFGRKKDALESAMKNGLWGHALLLASKMDNRTHARVMTRFAN-SLPINDPLQTVYQLMSGRMPAAATCCGDEKWGDWRPHLAMVLSNLTHTLDLDTRTISTMGDTLASKGLVDAAHFCYLMAQVGFG----------VYTKKSTKMVLISSNHSLPFLKFCSSEAIQRTESYEYAQSLGSQPLSLPNFQVFKFIYACRLAESGLCAQAFHYCEVISRTLLSLPEYYSPVFISQLIQMSLRLRFFDPQLKERP-----------EQELFIEPDWLLHLRQLDGQIKEGVISLRTDRSTPQL---------------------YPCSTPSSED---QCSPPEP-PALTPDPHNALMTSLVPP-----AAVQLMPPAPPTILQDGA-------------------VSLQQVPPPSESVPFYPVAPGPPQPNFV-APYQPEMQEQYMPMPPQIPQHMPPQMPTYNPAEMPPQMPQGMPGQMPPP---MHGAERGSAPSSPQQFPQPSPTFANPPPPGKD-FYDEMARLGPGRRSRTTSQSSMHMAPGRRSRTTSESSNHSGRERSSSFANQGSPPPPPIPEAPPQDVPERTKKDSPKKQGSGGGLLTWLFPKRKNEAHLPDDKNKSIVWDEKKQKWVNLDEPEEESKPPPPPPTGFPKAPMSAPAMVPPGVAGPPS----GPPVNMFSRRAG-TRSRYVDVLNPGRG-------------------------GAKAVASVPPPADLFAPLAPMAMPAN-------------------------------LFTPAAAPDEQQPMEGS--VPDTSGE--------------------------------NTLQTSATVPQMFNPNAALPPGPE--------GTQSGELSRSSSMSSLSREVSQHLNQAPAQQPVQGAPPAGGVTFYNPSQFAQSVPTN-RTRPGRLGQRGYPTPK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JEM2-1", "uniprot_id": "X2JEM2_DROME", "id": "X2JEM2-1", "name": "", "aln": "------MLHNNAPWLPPHQQQQQQAPQQHPTPQQQHAMPQQQQTLPAQQQQQQ--VYASQMFQQHQPNYWPEDQHQQQQQPQSLNYNNYFPGQQQQHPMQQQQLPPQQQLPPQQQQPTQQQHTIQQQLYYPTQQQPQVPAPAEP----------------ALDSFDNNNSGGGGGGGRSDG------------------------------WGDWGDWNDNSNNNNSNGTDGLLEPTGQLLEDSFNVQSSQGSWQAFATSNNVNNNGELPPPANPQSTSLQQQPLNQQSIPLLHQQPQSPPELGQEPELDAIVPPQAFQNQP--------------PTAAPPPTSLTSFSAQMTAVG---------------SPIYAVGASSAHSAGVGASPAPPTGVVAPPAHLAG-----------------------------------------------------------IGAPPAHLAGVGASPAPSALVGASPAPIIGVGAP------PVGAPPVGAPP-------------------ADATTIAPPAALPPSIVPSSGSNPFKRSTGLN---------KRVNIMADPAAGAPSPP----------------APAAAIAPVAP------------VAPIPPPADQLFGMPAEAHGEGFN--LIAAPPVEASLGTPLS-------------------APIPAPIPVPNASLYASPAVP--------------------------------QAFAHLEPDNQEVLSAPNDERAQYLQTSHLSEQLGEGEADQDAGLLPPPGLSRLVLGQPELDSQQQRQVTGATEQP---------PLNVAQAAALHMQE----RRADGEDTSDGEQQVRNIQTPPRRVVTGVETNAPSLREQREVVLDGEN---------------------LEDREAIPPPTLAELPTTSVHHNILPDEAEQLHHNNPPQAMTPLNAQQPHQQQSTLQQQHQQHSTTQQEKKR---------AAVGRRTTASLDLESDESDEFLQSERERDRERERRDLMEERHSRGRSHSHYPYEGETEDSVRGAAHHETKSLRETHHKRNHDSARSRRHQDPKVERERERDRERDRTWRRRSNKYHSGGEDPDRSYDHSRRYNNSNYEGESDNPEYN-H-MGDAELDGSGGRSSKTSRHRRSAAEEDFDDYERERNRSRRSTKPQSSAEKSRSSGGRRNYENSGRSARADDGRRRYQDQRNPGAQYPVSATGYVPYG-MYEQMSRNPQVYADMYAKFYGQMINSMNAAVS-AAASKGGVPAGAGVIPGLMPSAVPVSAAQLVAATS----GGSVSGSSEAAMLRERERYTHAYITQANEFHRHQYKELIYQQQQQQ---------------------QQQQQQQQQREDHLNSSFSVAEDNASFYGSHGGGSIYNQYQSYPLSSARSLSN--LNGDGRNSRCGPYYAGSECGLDIRAAADAAPSTYGGVAGTAGPVTNTAVARPPRRRTPLQFSRPHLVASYAMS-LLLKVKPKYAGRGR--LRNDVEVAPPRIRDGTSSLLRMYPGPLQGRKLHKDKIISFCKEQIRLGPTKGCTALYATQKKPQGSVTKYRASHALMWHLLILLLRQNGYIADTDVGDLLLENQQEYPYDPSEFEAENEPDADAEQDAAAPADKTVDSDLDSESAAGVTPAEPLAAGAATSSINGADAANAATPLSEQAATDKFRSYVLRGNVEEALQWATDNGLWTHAFFLALYEDRYALTDVAQKFLNRAIKANDPLQTLYQMKSCHTPACVSQLRDEQWGDWRSHLSILVTNKSRQPEYDRSSVVALGDTLFQRGDIYAAHFCYLVAQEEFGRYDSSATELTTLTANVPRLILLGSSHYKHFNEFASNEAIIMTEIYEYARSLFDPKFSIAHFQHYKFLLATRILDYGQHFRCTNYLEQIARHIELKPESYDSNFIQRVCGLAERLRYHDPILINRVSFASPPNATSKDSAAAEEKAWLRQLRSLAYVQPQQEQLQQLQQNQQVQQEQNDIDQQFAEVNKQFRELNMQYESNSNMENTLQPQLPPVDQQPPQQQQQVLSESYQQPTQQYYEPPPQAPTESDPYGQGQPSYYDPNAGQLHYDPNAAQHQYDQQQPQPQPTPSYGQIEPGTEAYQPGQATADPAAVPSGYGYDYWSGTQQPPYGDEPNENQAALKDEEEEDEEQDEQQILQYAKQQILQQTKQQQLQQEQHTRSNGAASINNRFKSNALKQERSSGSLRKRQE--------ASRTATIAAAAAAIAQITPATVAAAATPPAASAKAFNLNDVSSFSSTNKRHQATSSSNNRSSSNQAAAAAAATKAAAIATVPAAPNQLLSCRKSNSQNSPYLATPKTLTTPTRFIAAKAATVTATPTAPATSTTTSTTIGARGSSTKRVYFNLPSTIAESEQEFEHELDYDEEMEEENSMALAQAKPNVHLARKPHIVFNGTYPIDMPLTQGQSQLKSNSYDPEANADRGDLQRYRNYMLHDYVIDEDAEGEEQAEEEGEEDEYGDGDEDLFPYADDDESFDDGDYYTHQLLNKYGIIPSGEKQRVERTPASVEAATSAAQPQHVWSMKELIANPAIPLNYKKMCSEVEQSLSRFENYLDSKKEQQVPPGAAVRTFDIDAPTRRGHRSSTSTNAGLDLRSKKKL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48415-1", "uniprot_id": "SEC16_YEAST", "id": "P48415-1", "name": "COPII coat assembly protein SEC16", "aln": "--MTPEAKKRKNQKKKLKQKQKKAAEKAASHSEEPLELPESTINSSFNDDSVNRTESDIASKSDVPPVSSSTNISPANETQLEIPDTQELHHKLLNDSDQHDITADSNDLPDNSIVEHDSVITQTKPAMSQEYEETAAHLSSRNPSLDVVAGELHNNNEHTQKIAVSAVEEDSFNEEEGENHDS-------------------------IIISSLNDATPSQYNHFLPSDGNLLSPELSSGDTPTHNVPLGTKDNEINDDEYCNDKEISLNANNVLPDELSKEEDERLKLETHVSTEEKKQDIADQETAENLFTSSTEPSEN--------------KIRNSGDDTSMLFQDDESDQK---------VPWEEDVKKDFHNENTNNTQESAPNTDDRDKGYEGNEALKKS----------------------------------------------------------ESCTAADERSYSEETSEDIFHGHDKQVVEGQNDFTGKNIENESQKLMGEGN------------------HKLPLSAEADIIEPGKDIQDQAEDLFTQSSGDLG-----EVLPWESTDKNADVTSKSQE-----------KHEDLFAASGNDEKLPWEVS-------DGEVSSGKTENSMQTSTEKIAEQKFSFLENDDDLLDDDDSFLAS------------------SEEEDTVPNTDNTTNLTSKPVE------------------------------EKKASRYKPIIEEEAGMRQEQVHFTNTTGIVTPQQFHGLTKTGLGTPNQQVSVPNIVSPKPPVVKDNRSNFKINEEKKK-------SDAYDFPLEIISESSKKGHAKPVAVPTQRFGSGNSFSSLDKPIPQSRKGSNNSNRPPVIPLGTQEP------------------------RSSRTNSAISQSPVNYAFPNPYKIQQLQQAPIQSGMPLPNTNIPPPALKVETTVSAPPIRARGVSNASVGS-------SASFGARHATQYGLNNGVPPVSPYGQATINLPTANKYAPVSPTVQQ------KQYPSVVQNLGASAVNTPNFVKTHRGHTSSISSYTPNQNEHASRYAPNYQQSYQVPYTSQPVGPVAGNSSYQSQTRSSYAVPMMPQAQTSASIQPHANIQPPTGILPLAPLRPLDPLQAATNLQPRASNITAANSLPLANLPLAENILPEIITHRATSSVAPPRQENNPIKIDNEALLRRQFPIFHWSAANKVVYAVPPIPDQSQYMISSSIVQEIKVTPIDQIIKPNDMLKSFPGPLGSAKLKKKDLTKWMETTIKSISENES-STDMTIWQLLEMKLNDKVNWKNISKLLYNSDELLMYLSQPFPNGDMIPN---------AYRLDINCQMRVLAFLQTGNHDEALRLALSKRDYAIALLVGSLMGKDRWSEVIQKYLYEGFTAGPNDQKELAHFLLLIFQVFVGNSKMAIKSFYTNNETSQWASENWKSIVAAVLINIPENNEDP-LLIPPVVLEFLIEFGIFLTKKGLTAAASTLFIIGNVPLSNEPVMADSDVIFESIGNMNTFESILWDEIYEYIFS-------------------YDPKFKGFSSILPQKIYHASLLQEQGLNSLGTKYTDYLSSSVR--------KLPKKDILTINLTRELSEVASRLSESNTGWLAKPKLSSVWG---------------QLDKSFNKYIGGDDIDALNKKNDKKKVFDGFTPG--------SSANSSTVDLTQTFTPFQA-QVTSQSYVDTTALLHNAHNVPSHSVLHSKPSNVSKGLVEANLPYTHRIGDSLQGSPQRIHNTQFAAAEPQMASLRRVRTDQHTN------------EKALKSQQILEKKSTAYTPQFGQNHSVPMEKSNSNVPSLFADFPAPPKLGTVPSNYVSSPDLVRRESIISTGSEFLPPPKIGVPTKANSSQGSLMYSPSVEALPIDPVVPQVHETGYNDFGNKHSQKSMPEDESHTSHDNSNADQNTLKDSADVTDETMDIE-------------------GPGFNDVKNLLPMEPNHQPTSTVNPIQTISDDIQPILQTNVEVRGTDASKMENSLPSIENERS-------------------SEEQPENISKSASSAYLPSTGGLSLENRPLTQDENSISETVQSTYLPAGSISMEAKPISQVQDVPRNVNN--------------------KASKLVEQHMAPPKPKSTDATKMNYSPYVPQSTAASAD--------------GDESTILKTSPAIYARTHQAHASNPSQYFPLVNQANETASFELSESTSQAQSNGNVASENRFSPIKKAEVVEKDTFQPTIRKASTNQYRAFKPLESDADKYNDVIEDESDDDNMSTDEAKNRKEEKKNVN-MKKETKPSNKDIDDKSNGWFGWLKKDTG-------------------------DKKVYKAKLGHKNTLYYDEKLKRWVN---------------------------------KDATEEEKQKIIESSAPPPPPIVKR-------------------------------KDGGPKTKPRSGPINNSLPPVHATSVIPNNPITGEPLPIKTSPSPTGPNPNNSPSPSSPISRISGVNLTSKKANGLDDLLSLAGGPKPASTRRKKKTARGYVNVMDNIQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : .. . :. . . . . . : . . . . :: .. .: . : . . : . . . . : : * . . . . .. . * . : ... . . . : .:: * . : : . . : : . . : . : :: : . . : . .. . : ..: * . . . : : : . :: . . . : ... : . : :. . . . . . . * . . . : : : : : . .: . .. . . . . .: . . . . * : * :: .. . : : . :. . . .: .: . . ** .*. .*. : * . : . :. . . ... . . : : . :..:: . : . : . * : :. ::* : . : .. : .: . : : :. . : : : :* . * : : :: . :: .. :* ..:: : . . ** . . : * :. * .. . : : . ** : : .. .. * : : . : . . . . . : . .. : . . : : ..:. . . . . : . :: :.: . . . . . . :.. . . : . : : : : . : . . . : . ", "identical_positions": 24, "similar_positions": 296, "identity": "0.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-713", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99PG0-1", "uniprot_id": "AAAD_MOUSE", "id": "Q99PG0-1", "name": "Arylacetamide deacetylase", "aln": "-MG-KTISLLISV-VLVAYYLYIPLPDAIEEPWKVVWETAFVKIGTDLASFGELLGISHFMETIQLLMSFQEVPPTSDEHVTVMETAFDSVPVRIYIPK--RKSMALRRGLFYIHGGGWCLGSAAHFSYDTLSRWTAHKLDAVVVSTDYGLAPKHHFPRQFEDVYRSLRWFLQEDVLEKYGVDPRRVGVSGDSAGGNLAAAVTQQLIQDPDVKIKLKVQALIYPALQALDTNVPSQQEGSHFPVLTRSLMVRFWSEYFTTDRGLEKAMLLNQHVPMESSHLLQFVNWSSLLPERYKKSPVYKNP----TPGSSELAQKYPGFIDVKACPLLANDNILHHLPKTYIITCQYDVLRDDGLMYVKRLQNVGVHVTHHHVEDGFHGTFSF----PGLKLSERMKNQYLSWLIKNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22760-1", "uniprot_id": "AAAD_HUMAN", "id": "P22760-1", "name": "Arylacetamide deacetylase", "aln": "-MGRKSLYLLIVG-ILIAYYIYTPLPDNVEEPWRMMWINAHLKTIQNLATFVELLGLHHFMDSFKVVGSFDEVPPTSDENVTVTETKFNNILVRVYVPK--RKSEALRRGLFYIHGGGWCVGSAALSGYDLLSRWTADRLDAVVVSTNYRLAPKYHFPIQFEDVYNALRWFLRKKVLAKYGVNPERIGISGDSAGGNLAAAVTQQLLDDPDVKIKLKIQSLIYPALQPLDVDLPSYQENSNFLFLSKSLMVRFWSEYFTTDRSLEKAMLSRQHVPVESSHLFKFVNWSSLLPERFIKGHVYNNP----NYGSSELAKKYPGFLDVRAAPLLADDNKLRGLPLTYVITCQYDLLRDDGLMYVTRLRNTGVQVTHNHVEDGFHGAFSF----LGLKISHRLINQYIEWLKENL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5H8-1", "uniprot_id": "A0ACD6B5H8_DANRE", "id": "A0ACD6B5H8-1", "name": "Neutral cholesterol ester hydrolase 1", "aln": "MMRSKGVFVLVLLGALTAYHVYSPIPSDIEERWKLMVTDSFFKSLSQLAELSEQVGLLDYMRVMMFITIAERVVPVSDDRVQVAEENFDGVEVIVYQPNQLEQTGELRRAIIYLHGGGWCLGSSRMGPYDLLARHMVKELNAVIVAVEYRLAPAYHFPVQFEDVHRVVKYFLQNDVLKRYNINPERIAVSGDSAGGNLAAAVAQQLRKDPEQHIQLKAQALIYPVLQALDLKTPSYQQNQHMPILPRTLMVRFWSEYFTSDKSFLRAMMANTHNNHESAALLKFVNWSSYLPDSYRQTYNYSAPPVLTGKGPVRSIGAHHLLADPRASPLLVPDTALRFLPKAYVLTCEYDVLRDDGLMYVTRLRNAGVDVTHEHYPSGFHGALMFTVWPTDFEIGHRMTNNYITWLKQNL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : :*: * **::* *:*. :** *::: :..* :** : * :*: .:* : .: :.* *.**:.* * * *:.: * :* *: .:: ***.::*:******:**: ** *:* ...*:**:*:.:* *** :*** *****:. :::**::.** :*.::*.*:.:*************:*** .**: :*:** *:****.**.** . ** *:..:: .*.::***********:*:.: :**: . * **: *::****** **: : : *. * *. . : : * :*.***. *. *: ** :*::**:**:*********.**:*.**.***.* .****:: * .:::..*: *:*: ** :**", "identical_positions": 175, "similar_positions": 132, "identity": "42.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-719", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZR96-1", "uniprot_id": "D3ZR96_RAT", "id": "D3ZR96-1", "name": "", "aln": "MLDMSEARAQPPCSPSGTASSMSHVEDSDSDAPPSPAGSEGLG-RAG---GGGRGDTAEAADERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGTLKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKTGRSDSDSGTELGHHPGG-PMYKTDTVLGDAHRHSD-HTGQTHGPP--------------------------------------------------------------TPPTTPK-TDLHQASNGSKQELRLEGRRLVD--------------SGRQNIDFSNVDISELSSEVISNMDTFDVHEFDQYLP-LNGHSALATEPSQATASGSYGGASYSHSGATGIGASPVWAHKGAPSASASPTEAGPLRPHIKTEQLSPSHYNDQSHGSPGRA-DYGSYSAQASVTTAASATAASSFASAQCDYTDLQASNYYSPYPGYPPSLYQYPYFHSSR-------RPYASSLLNGLSMPPAHSPSSNWDQPVYTTLTRP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04886-1", "uniprot_id": "SOX8_MOUSE", "id": "Q04886-1", "name": "Transcription factor SOX-8", "aln": "MLDMSEARAQPPCSPSGTASSMSHVEDSDSDAPPSPAGSEGLG-RAG---GGGRGDTAEAADERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGTLKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSVKTGRSDSDSGTELGHHPGG-PMYKADAVLGEAHHHSDHHTGQTHGPP--------------------------------------------------------------TPPTTPK-TDLHQASNGSKQELRLEGRRLVD--------------SGRQNIDFSNVDISELSSEVISNMDTFDVHEFDQYLP-LNGHSALPTEPSQATASGSYGGASYSHSGATGIGASPVWAHKGAPSASASPTEAGPLRPQIKTEQLSPSHYNDQSHGSPGRA-DYGSYSAQASVTTAASATAASSFASAQCDYTDLQASNYYSPYPGYPPSLYQYPYFHSSR-------RPYASPLLNGLSMPPAHSPSSNWDQPVYTTLTRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P57073-1", "uniprot_id": "SOX8_HUMAN", "id": "P57073-1", "name": "Transcription factor SOX-8", "aln": "MLDMSEARSQPPCSPSGTASSMSHVEDSDSDAPPSPAGSEGLG-RAGVAVGGARGDPAEAADERFPACIRDAVSQVLKGYDWSLVPMPVRGGGGGALKAKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRVQHKKDHPDYKYQPRRRKSAKAGHSDSDSGAELGPHPGGGAVYKAEAGLGDGHHHGD-HTGQTHGPP--------------------------------------------------------------TPPTTPK-TELQQA--GAKPELKLEGRRPVD--------------SGRQNIDFSNVDISELSSEVMGTMDAFDVHEFDQYLP-LGG--PAPPEPGQA-----YGGA-YFHAGAS-----PVWAHKSAPSASASPTETGPPRPHIKTEQPSPGHYGDQPRGSP----DYGSCSGQSSATPAAP---AGPFAGSQGDYGDLQASSYYGAYPGYAPGLYQYPCFHSPR-------RPYASPLLNGLALPPAHSPTSHWDQPVYTTLTRP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ITJ3-1", "uniprot_id": "A0A0R4ITJ3_DANRE", "id": "A0A0R4ITJ3-1", "name": "", "aln": "---MSKEPDKAASIP-----ESCFLDDVDSDSPSSPSVSDDPGSRAAP-------PPDTDGDARFPVCIRDAVSQVLKGYDWSLVPMPMQGSR--SLKDKPHVKRPMNAFMVWAQAARRKLADQYPHLHNAELSKTLGKLWRLLSESEKRPFVEEAERLRLQHKKDYPDYKYQPRRRKSLKPGQNEAEAGAEKNLHHTD-PIYKTEAGMR-AMHHQTIHGVQPHGPP--------------------------------------------------------------TPPTTPK-SDQHQS-----------MKRLSE--------------NARQNIDFSNVDISELSSDVIGSISQFDVREFDQYLP-LNG--HTESGGGQHSSPGCFSTSFHHHSGAS------AWNK---PSGSPSTSSANQQRPLIKTEQLSPSHYG-QSHGSP----------TQSELS----------------DCADMQNSAYFTTFSGYPAGIYQYPYFHSTR-------RSYMTPVLNTLSSP-SHSPGTNWEQPVYTTLTRP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VA17-1", "uniprot_id": "Q9VA17_DROME", "id": "Q9VA17-1", "name": "", "aln": "---MSDSSSSNCSKDRAKPVETLVLANYALKAEQKKAQGQGGR----------------KEDER----ITTAVMKVLEGYDWNLVQASAKAPTD---RKKEHIKRPMNAFMVWAQAARRVMSKQYPHLQNSELSKSLGKLWKNLKDSDKKPFMEFAEKLRMTHKQEHPDYKYQPRRKKARVLPSQQSGEGGSPGPEMTLSATMGSSGKPRSSNSNGQRRAGKGNAAADLGSCASTISHANVGSNSSDVFSNEAFMKSLNSACAASLMEQSLIETGLDSPCSTASSMSSLTPPATPYNVAPSNAKASAANNPSLLLRQLSEPVANAGDGYGVLLEAGREYVAIGEVNYQGQSAGVQSGAEGGGAGQEMDFLENINGYGGYTGSRVSYPAYSYPANGGHFATEEQQQQQALQASEALNYKPAAADIDPKEIDQYFMDQMLPMTQHHHPHHTHPLHHPLHHSPPLNSSASLSSACSSASSQQPVAEYYEHLGYSPAASSASQNPNFGPQQPYANGAASMTPTLGDPAPQQELQSQQQEQQHQNPSQHHLWGTYTYVNP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **. . . . : : .: . : .:. * * * ** :**:****.** . :. : * *:**************** ::.*****:*:****:*****: *.:*:*:**:* **:**: **:::*********:*: .:: * . . . . :. . : : : :... ***:** :: :: : .*: : :.:*: . *: * . . .. : ::* :.* . . . : : . . :.: .. : : . :: : * ::. : .: * . . . * * :.. . *: *. :: . * ..*", "identical_positions": 90, "similar_positions": 119, "identity": "16.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-723", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VP61-1", "uniprot_id": "ACSA_DROME", "id": "Q9VP61-1", "name": "Acetyl-coenzyme A synthetase", "aln": "---------------MPAEKSIYDPNPAISQN-----------------------------------AYISSFEEYQKFYQESLDNPAEFWSRVAKQFHWETPADQDKFLKYNFNISKGPISIKWMEGASTNLCYNLLDRNVRN-GLGDQIAYYWEGNHPDDYSRGLTYRKLLEEVCRFANVLK-DHGIRKGDRVSIYMPMILELPIAMLACARIGAVHSIVFAGFSPDSLAERMFDCKAKLLITADGAWRGEKPLYLKALCDTALEKVEEMGHS-VEKCIVVSHLKRVTPCQPDHVEEEIPWTDDRDYWWHEEMEDKEPACYPEWMDAEDPLFMLYTSGSTGKPKGVLHTTAGYLLYAATTFKIVFDYKPGDIYWCTGDVGWITGHTYVVYGPLANGATSVIFEGTPFFPGNDRYWSVIDKYKVTQFYTAPTAIRALMKFGEGPVLKHNLSGLKVLGSVGEPINPEAWLWYYKYIGKEQCSIVDTFWQTETGGHVITPLPG-ATPMKPGSASFPFFGVKPTLLD-ECGIEIKG-EGEGYLVFSQPWPGMMRTLYNNHERFEDTYFSKFPGYYCTGDGARRDADGYLWITGRVDDMLNVSGHLMSTAEVESVLTEHPRVAESAVVSRPHPVKGECLYCFITPNENEVFDQKLIS------------DLKKMVRERIGPFAMPDVIQNAPGLPKTRSGKIMRRVLRKIAVNDRN-VGDTSTLADEQIVEQLFANRPVEAK-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1P3X2-1", "uniprot_id": "A0A8M1P3X2_DANRE", "id": "A0A8M1P3X2-1", "name": "Acetyl-coenzyme A synthetase", "aln": "MSPVSDSTNTALSSPKEPEEKIYHPPDGIFTD-----------------------------------AHVPDFDAYLALYKKSIEEPEEFWGDVAQEFFWKKPPS-GQMLQYNFDVTKGSVFIKFMDGAKTNICYNVLDRNVHERNLGDKVAYYWVGNSPDHHLT-ITYNQLLRNVCRCANALK-LLGVKKGDRVAIYLPMIPELVYTMLACARIGAVHSIVFAGFSSESLCERIMDAQCNILVTADGVYRGDKLINLKKIASEALDRCKESSASSVQKCVVVKHPAFITSSDAS-SSLQTPWDELCDIWWDDLMDGVSDECEPEWMDSEDPLFILYTSGSTGKPKGVVHTVTGYMLYTSLTFKYVFDYHHDDVYWCTADIGWITGHSYITYGPLANGATSVLFEGVPVHPHVGRLWEIIEKYGVSKFYTAPTAIRLLMKYGKEPLQRYDLSSLRVLGTVGEPINPEAWLWYYDVVGQQRCPVIDTFWQTETGGHVLTPLPA-ATPLKPGSATCPFFGVQPAILN-EHGEELEG-EAEGYLVFRQPWPGIMRGVFGNQERFESTYFRKFPGFYVTGDGCRRDKDGYYWITGRIDDMLNVSGHLLSTAEVESALSEHPSVAEAAVVSCPHAVKGECLYCFITLKDQQEFNRTLMD------------ELKRKVREKIGPIATPDFIQNAPGLPKTRSGKIMRRVLRQIARNEKE-LGDLSTLADPKVVEVLFSQRCEAAA-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P52910-1", "uniprot_id": "ACS2_YEAST", "id": "P52910-1", "name": "Acetyl-coenzyme A synthetase 2", "aln": "---MTIKEHKVVYEAHNVKALKA--PQHFYNSQPGK-------------------------------GYVTDMQHYQEMYQQSINEPEKFFDKMAKEYLHWDAPYTKVQSGSLNNG-----DVAWFLNGKLNASYNCVDR--HAFANPDKPALIYEADDESDNKI-ITFGELLRKVSQIAGVLK-SWGVKKGDTVAIYLPMIPEAVIAMLAVARIGAIHSVVFAGFSAGSLKDRVVDANSKVVITCDEGKRGGKTINTKKIVDEGLNGVDL-----VSRILVFQRTG----------TEGIPMKAGRDYWWHEEAAKQRTYLPPVSCDAEDPLFLLYTSGSTGSPKGVVHTTGGYLLGAALTTRYVFDIHPEDVLFTAGDVGWITGHTYALYGPLTLGTASIIFESTPAYPDYGRYWRIIQRHKATHFYVAPTALRLIKRVGEAEIAKYDTSSLRVLGSVGEPISPDLWEWYHEKVGNKNCVICDTMWQTESGSHLIAPLAG-AVPTKPGSATVPFFGINACIIDPVTGVELEGNDVEGVLAVKSPWPSMARSVWNHHDRYMDTYLKPYPGHYFTGDGAGRDHDGYYWIRGRVDDVVNVSGHRLSTSEIEASISNHENVSEAAVVGIPDELTGQTVVAYVSLKDGYLQNNATEGDAEHITPDNLRRELILQVRGEIGPFASPKTIILVRDLPRTRSGKIMRRVLRKVASNEAEQLGDLTTLANPEVVPAIISAVENQFFSQKKK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q01574-1", "uniprot_id": "ACS1_YEAST", "id": "Q01574-1", "name": "Acetyl-coenzyme A synthetase 1", "aln": "MSPSAVQSSKLEEQSSEIDKLKAKMSQSAATAQQKKEHEYEHLTSVKIVPQRPISDRLQPAIATHYSPHLDGLQDYQRLHKESIEDPAKFFGSKATQFLNWSKPFDKVFIPDPKTGRPSFQNNAWFLNGQLNACYNCVDR--HALKTPNKKAIIFEGDEPGQGYS-ITYKELLEEVCQVAQVLTYSMGVRKGDTVAVYMPMVPEAIITLLAISRIGAIHSVVFAGFSSNSLRDRINDGDSKVVITTDESNRGGKVIETKRIVDDALRETPG-----VRHVLVYRKTN----------NPSVAFHAPRDLDWATEKKKYKTYYPCTPVDSEDPLFLLYTSGSTGAPKGVQHSTAGYLLGALLTMRYTFDTHQEDVFFTAGDIGWITGHTYVVYGPLLYGCATLVFEGTPAYPNYSRYWDIIDEHKVTQFYVAPTALRLLKRAGDSYIENHSLKSLRCLGSVGEPIAAEVWEWYSEKIGKNEIPIVDTYWQTESGSHLVTPLAGGVTPMKPGSASFPFFGIDAVVLDPNTGEELNTSHAEGVLAVKAAWPSFARTIWKNHDRYLDTYLNPYPGYYFTGDGAAKDKDGYIWILGRVDDVVNVSGHRLSTAEIEAAIIEDPIVAECAVVGFNDDLTGQAVAAFVVLKNKSSWSTATDDELQDIK-----KHLVFTVRKDIGPFAAPKLIILVDDLPKTRSGKIMRRILRKILAGESDQLGDVSTLSNPGIVRHLIDSVKL--------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: .:: * ::::*:::* :*:. * :: . :: ... * .** :** : :: * : .: .. :*: :**.:*.: * .*. *::*** *::*:**: * ::** :****:**:******. ** :*: * ..::::* * ** * : * : . .* * : :* : . * * *:*****:******** **** *:. **:* : * : .** : *: : :.*:******:* **** * ::::**..* .* .* * :*:.: .::**.****:* : : *. : .:. ..*: **:***** .: * ** . :*::. : ** ****:*.*:::**.. ..* *****: ****:.. ::: * *:: . ** *.. .**.: * :: :::*: .**: :**.* ****. :* *** ** **:**::***** :**:*:*: : :. *:*.***. . :.*: : .:: :: . . .* ** ***:* *. * . .**:*********:**:: .: : :** :**:: :* :: ", "identical_positions": 211, "similar_positions": 202, "identity": "28.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-726", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZQH5-1", "uniprot_id": "D3ZQH5_RAT", "id": "D3ZQH5-1", "name": "", "aln": "-------MWWGGRGQSFNIAPQKEEPELGFSGPKSDPGNRMPEP-----SSHQLG-SCLASGCLPGEHILAWAPGRRKG------------------------PGLE-----LPGTLICTNFRVTFQPCGWQR-----------NQDTPLSSEYDFALINIGRLEAVSGLSRVQLLRPGSQ---------------------LKFIPEEVLIHGRDFRLLRIGFEAGGLAPQAFQVTMAIIQARAQSSQ--VQQYRGITLS----KAGKVSGSRKPPIPLLETLEDWETERKKQGARGWRVSMVNERFDVATSLSG-------YFWVPNRILDSEVRRAFAHFHQGRGPRLSWHHPGGSDLLRCAGFYIASDPNKEDIRAVELMLQAGHS--DVVLVDTMDEMPSLADVQLAHLKLRALCLPDSS----VAEDKWLSALEGTRWLDYVRSCLRKASDISVLVTSRVRSVVLQERGDRDFNGLLSSLVQLLLAPEARTLFGFQSLVQREWVAAGHPFLTRLGETGAS------------EEAPVLPLFLDCAWQLLQQFPAEFEFSEFFLLALHDSIRVPDTLTFLRNTPWERGKKSGQFN-SYTQVYTP-EYSQPLAGSPANLHLS-VWDWDLRYSKEQISQFLNPGYDPEHCP----DSGLPRQQPSLMVPGSPSSMWLFSRGALTPLNQLCPWQD--STSLLTVSSHWLP-RPARSSESLADQEWGLPSHWGACP--------LPPGLLLPGYLGPQIRFWKRCYLRGRPEVQIGSSALT------ISGLQDELSHLQELLRKWTPRISPE--DHSKKRDPNTILS-------------QIC------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3V1L6-1", "uniprot_id": "MTMRB_MOUSE", "id": "Q3V1L6-1", "name": "Myotubularin-related protein 11", "aln": "-------MWWGGRGQSFNIAPQKEEPEMGLSGPKSNPGNRMPEP-----SSHQLG-SCLASGCLPGEHILAWAPGRRKG------------------------PGLD-----LPGTLICTNFRVTFQPCGWQR-----------KQDTPLSSENDFALINIGRLEAVSGLSRVQLLRPGSQ---------------------LKFIPEELLLHGRDFRLLRVGFEAGGLAPQAFQVTMAIIQARAQSSQ--VQQYRGITLS----KVGKVSGSRKPPIPLLETLEDWETECKKQGARGWRVSTVNERFDVATSLSG-------YFWVPNRILDSEVRRAFAHFHQGRGPRLSWHHPGGSDLLRCGGFYIASDPNKEDIRAVESMLQAGHS--DVVLVETMDEMPSLADIQLAHLKLRALCLPDSS----VAEDKWLSALEGTRWLDYVRSCLRKASDISVLVTSRVRSVVLQELGDRDFNGLLSSLVQLLLAPEARTLFGFQSLVQREWVAAGHPFLTRLGDTGAS------------EEAPVFPLFLDCAWQLLQQFPAEFEFSEFFLLALHDSIRVPDTLTFLRNTPWERGKKSGQFN-SYTQVYTP-EYSQPLAGSSANLHLS-VWDWDLRYSKEQISQFLNPGYDPEHCP----DSRFSRQQQSLMVPGPPSSMWLFSRGTLTPLNQLCPWQD--SSSLLAVSSHWLP-RPARSSESLADQEWGLPSHWGACP--------LPPGLLLPGYLGPQIRFWKRCYLRGRPEVQMGSSALT------VSALQDELSHLQELLRQWTPRISPE--DQSKKRDPNTILS-------------QIC------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A4FU01-1", "uniprot_id": "MTMRB_HUMAN", "id": "A4FU01-1", "name": "Myotubularin-related protein 11", "aln": "-------MWWGGRGQSFNIAPQKEEPEMG-----SVQENRMPEP-----RSRQPS-SCLASRCLPGEQILAWAPGVRKG------------------------LEPE-----LSGTLICTNFRVTFQPCGWQW-----------NQDTPLNSEYDFALVNIGRLEAVSGLSRVQLLRPGSL---------------------HKFIPEEILIHGRDFRLLRVGFEAGGLEPQAFQVTMAIVQARAQSNQ--AQQYSGITLS----KAGQGSGSRKPPIPLMETAEDWETERKKQAARGWRVSTVNERFDVATSLPR-------YFWVPNRILDSEVRRAFGHFHQGRGPRLSWHHPGGSDLLRCGGFYTASDPNKEDIRAVELMLQAGHS--DVVLVDTMDELPSLADVQLAHLRLRALCLPDSS----VAEDKWLSALEGTRWLDYVRACLRKASDISVLVTSRVRSVILQERGDRDLNGLLSSLVQLLSAPEARTLFGFQSLVQREWVAAGHPFLTRLGGTGAS------------EEAPVFLLFLDCVWQLLQQFPADFEFSEFFLLALHDSVRVPDTLTFLRNTPWERGKQSGQLN-SYTQVYTP-GYSQPPAGNSFNLQLS-VWDWDLRYSNAQILQFQNPGYDPEHCP----DSWLPRPQPSFMVPGPPSSVWLFSRGALTPLNQLCPWRD--SPSLLAVSSRWLP-RPAISSESLADQEWGLPSHWGACP--------LPPGLLLPGYLGPQIRLWRRCYLRGRPEVQMGLSAPT------ISGLQDELSHLQELLRKWTPRISPE--DHSKKRDPHTILNP-----------TEIAGILKGRAEGDLG------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F7E6-1", "uniprot_id": "E7F7E6_DANRE", "id": "E7F7E6-1", "name": "", "aln": "--------MLTGSKTTFKVR--QMVPDMK--------ERMMSHS-----SLHARGRDVLGLCCLPGECVLQRAVLVRKK------------------------LSAKEGGGWLSGTLFCTHFRVAFVPQDSQKP--------DDNADPVLLGDHDVALASIEKVVAVG-PSRTKLVTPTCS---------------------LKFTPEELVLYCRDLRVLCFLFDRLTPDTQAVEITYTIAKTYQPLKPGTILSFQNAALGSIEMKQFLSNRRRDPSMNWLECSLGWEQELERTGASGWRVSSVNDRFEMSTSLPR-------FNVVPQRVLDTELKKTFAHFNEGRIPRWCWRHPRGSDLLRMASFQNNIYHEKDDIRNLELVLFGGQQ--LCVIVDLGEEMPSPADIQLAHTRLRTLCLGDISSSVSVPDDKWLSTLESTRWLDYTRCCLRKAAEVCCLLRAGHMTVVLQEPEDRDMNCVVCSLVQVMCDPHCRTVAGFQGLVQKEWITAGHKFLSRINYHRESD----------KEEAPVFLLFLDCVWQLWAQYPARFQLTEDYLLALHDSVHLPLFSSFLANSQRERCRRSQHLPQSYTPVNGLRDVPMSVPEEPVDPPFPPVWDWALQYSSQRRARFTQPISQPTCPPPVLNGNLNTNLERSWHNDGLPGSVFLLSRSTFSHPSNLLPWRS--SNS----GSYWKSHRRAPSSESLSGLERLIRACSLSEPSENNTILHDPYEPLLPLLLGPCVRVWRSCYLRGALHAQAFSHPVSSCTQHPVDQLAWEVQQLREKLAQASNRRPENQIKHQEARRPESNLNQNANNGTFLFSSSRVSQQQQQQAPSSRGAAQSSAPPRPQRTASDPPRPAQRNSGKHTFLFGHQQEPQSGQRYIPSPSAKLHKRPGNSQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VY15-1", "uniprot_id": "Q9VY15_DROME", "id": "Q9VY15-1", "name": "Myotubularin phosphatase domain-containing protein", "aln": "MATGGGGSGHGGAGSAGNADHHKRNTFTSYVAPLPGDLRATADTNEWCLPSDLRDVHLAKPRLLHGEQIVASAPAYMYSPIDPMDSSGGSGSTLSAISSASGTPADRHHKEATFGLLSVTNFKLAFVPLHEKRNQAITAPLIDLYQENTYLGRNEITLNNIDHIYTITELGRAASALQAARGMASHAGMSRRKKLEPFKQQNISGRIAALHIVCKNFRLLKFAFQQQDSKMFGASDQGKLIASALVRFAYPMRHDLSFAYAH---REPYYSTLGASGTSMYATKNDWARELIRCGATEWQVVSCASVQLLQNPLQAGKYTVPPHFVIPKSCSVDRFLDLSRAFCDSRAAFWVYSYGSSAALVRLAELQPAAQQDTKSENVMLELVRKCDAGRQLKLLQLTDRLPSIQDVLRAYQKLRRLCTPETPEKFMLQDDKYLGLLEKTNWLFYVSLCLRYASEASATLRSGVT-CVLQESNGRDLCCVISSLAQLLLDPHFRTIDGFQSLVQKEWVALEHPFQRRLGHVYPAQPAGGNAELFDSEQSPVFLLFLDCVWQLLQQFPDEFEFTQTYLTTLWDSCFMPIFDTFQFDTQAQRLK----------------------AVTDSQLVLRPVWDWGEQFSDKDKMFFSNPLYQRQRGD----------LGAQAAAVAHRRSLAVGSKGAHGAASGVTPSRNTINPQLFATASSVPQDRYLQPAHRIFDLQVWDQCYYRWLP-----------ILDIRGGGQPQVDLYHRLLLSNIAKVQRCLDYQN---------FDDLPDAYYEFAGESRPNQHKD--EKPDKEDEAEFVDG-------------VERRRKPTAKAATPTSGLTSVTGNLQLSTLSSFFPFGNPIAGDAPLQLYDILSSSSELLMETSSFLDKSSIV--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : : . . ... . * ** :: * * * *:*:::* * : : . :.:* .* :: :: .*. . . : : :::*:* . *: . . : : . : . : . . .* * : .* *:* . : ..* . :*: .. * :.* . : : .: *:* . : :... . : :: . ::: :.:** *: *: :** ** : . : :**:*. ** *.** *. *** *:: . : : :*** .**: ::.**.*:: *. **: ***.***:**:: * * *:. : *::**: *****.*** *:* *:::: :* :* ** :* :* :: :* : . : : **** ::*. * :* : . . *: : *:.: . : * :. . . .* * .:. : . : . * : * : .:: * . ..* . : . * : . : .: . . :. : ", "identical_positions": 109, "similar_positions": 187, "identity": "11.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-730", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2KF05-1", "uniprot_id": "BRPF3_MOUSE", "id": "B2KF05-1", "name": "Bromodomain and PHD finger-containing protein 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------MRKPRRKSRQNAEGRRSP-SPYSLKCSPTRETLTYAQAQRIVEVDIDGRLHRISIYDPLKIITEDELTAQDITECNSNKENSEQPQFPAKSKKPSSKGKRKESCSKHASG----------TSFHLPQPSFRVVDTGSQPEAPPLPAAYYRYIEKPPEDLDAEVEYDMDEEDIAWLDMVNEKRRADGHSSVSADTFELLVDRLEKESYLESRSS-----------------------GAQQSLIDEDAFCCVCLDDECHNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRCCLQSPSRPVDCVLCPNKGGAFKQTSDGHWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICKQKGLGAAIQCHKVNCYTAFHVTCAQRAGLFMK--IEPMRETSLNGTTFTVRKTAYCEAHSP-SVAVARRKGDSPRSLSEVGDEDGPKEGGGEEEQEE-AEEEGQEGQGGVGSPLKGVSKKGKMSLKQKIKKEPEEAGREAPSITLPMVTVPQIPSYRLNKICSGLSFQRKTQFMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQREQD--EKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAMELELMPFTVLLRTTLDLLQEKDSAHIFAEPVSLSEVPDYLEFISKPMDFSTMRRKLESHLYHTLEEFEEDFNLIVTNCMKYNAKDTIFHRAAVRLRDLGG-----------------------------------------------------------------------------------------AILRHARRQAENIGYDPERGTHLPESPRLEDFYRFSWEDVDNILIPENRAHLSPEAQLKELLEKLDLVSTMRSSGAR--------------TRRVRMLRREINALRQKLAQPPPPQLLSLNKTVPNGELPAGSRGDTAVLEQAQQEEPEEEGDRDDSKLPAPPTLEPTGPAPSLSE-----------------------------QESPPDPPTLKPISDSKPSSRFLKSRKVEDEELLEKSALQ-------------------LGSEPLQCLLSDNGIDRLSLTNPDSHPDTPLGTVGRRTSVLFKKAKNGVKLQRG-----PDGT--LENGEDHGPEDDPASPASTEDEHYSRKRPRSR----SCSDSEGERSPQQEEETGVTN----------------------------------GFGKHTESGSDSECSLGLSGGLAFEAGSGLTPPKRS---------RGKPALSRVPFLEG--VNGDSDHSGSGRSLLMPFEDHGDLEPLELVWAKCRGYPSYPALIIDPKMPREGLLHNGVPIPVPPLDVLKLGEQKQAEAGERLFLVLFFDNKRTWQWLPRDKVLPLGVEDTVDKLKMLEGRKTSIRKSVQVAYDRAMIHLSRVRGSHAFVTSSYL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AAK8-1", "uniprot_id": "A0A8I6AAK8_RAT", "id": "A0A8I6AAK8-1", "name": "", "aln": "MGRGGDARALPWSEGGDEARESAREGAAKRGPPPAPAILFLPGPGSGAAKPRPPRALLLARPEQSSALKGPPLAHGFPLDGQAGRPISARISASLPSSPSPSFAGARFPCEKGSDFASVCGLSSSFPVAMRKPRRKSRQNAEGRRSP-SPYSLKCSPTRETLTYAQAQRIVEVDMDGRLHRISIYDPLKIITEDELTAQDITECNSNKENSEQPQFPAKSKKPSSKGKKKESCSKHAPG----------TSFHLPQPSFRVVDTGSQPEAPPLPAAYYRYIEKPPEDLDAEVEYDMDEEDMAWLDMVNEKRRADGHSSVSADTFELLVDRLEKESYLESRSS-----------------------GAQQSLIDEDAFCCVCLDDECHNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRCCLQSPSRPVDCVLCPNKGGAFKQTSDGHWAHVVCAIWIPEVCFANTVFLEPIEGIDSIPPARWKLTCYICKQKGLGAAIQCHKVNCYTAFHVTCAQRAGLFMK--IEPMRETSLNGTIFTVRKTAYCEAHSP-SVATARRKGDSPRSLSEVGDEDGLKEGGGEEEQEE-GEEEGQEGQGGVGSPLKGVSKKSKMTSKQKIKKELEEAGRETPSITVPMVTVPQIPSYRLNKICSGLSFQRKNQFMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQREHD--EKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAMELELMPFTVLLRTTLDLLQEKDPAHIFAEPVSLSEVPDYLEFISKPMDFSTMRRKLESHLYHTLEEFEEDFNLIVTNCMKYNAKDTIFHRAAVRLRDLGG-----------------------------------------------------------------------------------------AILRHARRQAENIGYDPERGTHLPESPKLEDFYRFSWEDVDNILIPENRAHLSPEAQLKELLEKLDLVSAMRSSGAR--------------TRRVRMLRREINALRQKLAQPPPPQLLSLTKTVPNGELPAGSRGDAAGLEQTLQEEPEDEGDRDDSQLPAPPTLEPTGPAPSLSE-----------------------------QESPPDPPTLKPISDSKPSGRLPKPRKVDDEELLGDSALQ-------------------LGSEPLQCLLSDNGADRLPLTNPDSPPGTPLGNVGRRTSVLFKKAKNGVKLQRG-----PDGT--LENGE-----DAPASPASMEEEHCSRKRPRSQ----SCSDSEGERSPQQEEETGVTN----------------------------------GFGKHTESGSDSECSLGLSGGLAFEAGSGLTPPKRS---------RGKPALSRVPFLEG--VNGDSDHSGSGRSLLMPFEDRGDLEPLELVWAKCRGYPSYPALIIDPKMPREGLLHNGVPIPVPPLDVLRLGEQKQAEAGERLFLVLFFDNKRTWQWLPRDKVLPLGVEDTVDKLKMLEGRKTSIRKSVQVAYDRAMIHLSRVRGSHSFVTSSYL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ULD4-1", "uniprot_id": "BRPF3_HUMAN", "id": "Q9ULD4-1", "name": "Bromodomain and PHD finger-containing protein 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------MRKPRRKSRQNAEGRRSP-SPYSLKCSPTRETLTYAQAQRIVEVDIDGRLHRISIYDPLKIITEDELTAQDITECNSNKENSEQPQFPGKSKKPSSKGKKKESCSKHASG----------TSFHLPQPSFRMVDSGIQPEAPPLPAAYYRYIEKPPEDLDAEVEYDMDEEDLAWLDMVNEKRRVDGHSLVSADTFELLVDRLEKESYLESRSS-----------------------GAQQSLIDEDAFCCVCLDDECHNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRCCLQSPSRPVDCILCPNKGGAFKQTSDGHWAHVVCAIWIPEVCFANTVFLEPIEGIDNIPPARWKLTCYICKQKGLGAAIQCHKVNCYTAFHVTCAQRAGLFMK--IEPMRETSLNGTIFTVRKTAYCEAHSPPGAATARRKGDSPRSISETGDEEGLKEGDGEEEEEEEVEEEEQEAQGGVSGSLKGVPKKSKMSLKQKIKKEPEEAGQDTPS-TLPMLAVPQIPSYRLNKICSGLSFQRKNQFMQRLHNYWLLKRQARNGVPLIRRLHSHLQSQRNAEQREQD--EKTSAVKEELKYWQKLRHDLERARLLIELIRKREKLKREQVKVQQAAMELELMPFNVLLRTTLDLLQEKDPAHIFAEPVNLSEVPDYLEFISKPMDFSTMRRKLESHLYRTLEEFEEDFNLIVTNCMKYNAKDTIFHRAAVRLRDLGG-----------------------------------------------------------------------------------------AILRHARRQAENIGYDPERGTHLPESPKLEDFYRFSWEDVDNILIPENRAHLSPEVQLKELLEKLDLVSAMRSSGAR--------------TRRVRLLRREINALRQKLAQPPPPQPPSLNKTVSNGELPAGPQGDAAVLEQALQEEPEDDGDRDDSKLPPPPTLEPTGPAPSLSE-----------------------------QESPPEPPTLKPINDSKPPSRFLKPRKVEEDELLEKSPLQ-------------------LGNEPLQRLLSDNGINRLSLMAPDTPAGTPLSGVGRRTSVLFKKAKNGVKLQRS-----PDRV--LENGEDHGVAGSPASPASIEEERHSRKRPRSR----SCSESEGERSPQQEEETGMTN----------------------------------GFGKHTESGSDSECSLGLSGGLAFEACSGLTPPKRS---------RGKPALSRVPFLEG--VNGDSDYNGSGRSLLLPFEDRGDLEPLELVWAKCRGYPSYPALIIDPKMPREGLLHNGVPIPVPPLDVLKLGEQKQAEAGEKLFLVLFFDNKRTWQWLPRDKVLPLGVEDTVDKLKMLEGRKTSIRKSVQVAYDRAMIHLSRVRGPHSFVTSSYL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BGP9-1", "uniprot_id": "A0A8M2BGP9_DANRE", "id": "A0A8M2BGP9-1", "name": "", "aln": "-------------------------------------------------------------------------------------------MRKLRKRVAQSRAGG-------------FGRGLVREEDQDQVGPSSHVDMDALLCPPSPCRLNFSPTRDTLTYAQAQRMVEIELEGRLHRINICDQLSVVTEDEMLAQDLTECNSNKENSEQRQGNKQAASKSKKKDGKHTAKKKSGGQYGLQGQVAHLQAPLPKPTFRKLDNFTVSDAPPLPVAYYRYMEKSGEELDNEAEYDMDEEDMAWLEMVNQKRVSDGHASVPPDTFELLIDRLERESILESRSQ-----------------------ALSQSTIDEDAYCCVCLDDECLNSNVILFCDICNLAVHQECYGVPYIPEGQWLCRRCLQSPSRPVDCVLCPNRGGAFKQTSDGSWAHVICAIWIPEVCFANTVFLEPVEGVKNIPPARWKLTCYLCKQKGRGASIQCHKANCYRAFHVTCAQRAGLYMK--IDPVRETGTNGTTFTVKKTAYCENHSP------------PGTGTEGYEDNGLVGGRGNRGQRS----------YTLGPPLQQNQNGRKKGSAAQQKKTQKNSGGGSRKTGVPLLLVPQIPSFRLNKICTGVSVERKNQFMQRLHNYWLLKRHSRNGVPLIRRLHSHLQAQK-SEQREPD--AKLQAVREELKYWQKLRQDLEKARLLIELIRKRERLKREQMKLQQAALELQLTPALVFLRATLEQLKEKDTDHIFTTPVNLKEVPDYLEFVTVPMDFSTMHDKLEAHKYSSVADLENDFNLMVSNCLRYNSNDTVFHKAAMQLREVGG-----------------------------------------------------------------------------------------AILRHAQHQALSIGLDPSTGMHLPDKPIPHNTTVSWCDEVDMLLDPDNRVHMCAEDQLKTLLDKLDLVASMRTSGGR--------------TKRMRLLRREINSLRHKISHQDRNSRLLNGKIREEKSKDAKSE---KKMDYITSEDPKKSASQKAQEPACPASSPLPGDAPPNPP-----------------------------LFCLETGRTTTPAQSNKPGSRKQRAKGKDRSLRENHNQTP-------------------KEDENFHTKENDSSPQEDRVCSAKNQSDSPKIGVGRRTSILFKKAKNGARPTKDKPVLLPNGVSKAQNGASQEQNTQAKAPSTPKPVSPSPHQLRSRG-LSTCSDGEGMKANSLPEENGLTN----------------------------------GLKRHNGNSSDSENST-----PAFPTHS-SSPPKRS---------RGKPALSKVPVDEE--KNEVTNTNSEAS------QNDGEMEPLTLVWAKCRGYPSYPAMIVDPKMPQEGILHNGIPIPVPPTDVLDLGKRRQEESEEKLFLVLFFDTKRTWQWLPQDKLHHMGIDDTVDRLRLMEGKKPNVRKSVHTAYDRAMTHLSHVQENSSFNPSNFI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7JVP4-1", "uniprot_id": "BRDH_DROME", "id": "Q7JVP4-1", "name": "Bromodomain-containing protein homolog", "aln": "----------------------------------------MGLDFDAVEYCKGVKTQQSQPPFACPVRGCDRSYKTIMGLQYHLMKYDHDNPQPLTPVLTPSRKKARSRSGGHHSTPRPHKDHPTPGGGGAEARNGCSSASAGGGSASGVSARQYANPESLVSYNEEEATVTFNLDGKSVRLGIDDALPLVEDEEFAALVARGCILNADAPPLEENAPWAR------------------------------VQVPVARVAEIPDYRVSDAPPRPLAYYRFIEKSLEELDGEVEYDVDEEDSAWLEHMNEERQRLGLNAVGIDTMELLMDRLEKESHFQAAANG----------------------TPTGVEVDDDAVCCICLDGECQNTNVILFCDMCNLAVHQDCYGVPYIPEGQWLCRRCLQSPSKPVNCVLCPNAGGAFKQTDHGQWAHVVCALWIPEVRFANTVFLEPIDSIETIPPARWRLTCYVCKEKGLGACIQCHRNSCYAAFHVTCAQQAGLYMT--MDTVKDG-HNDSSMHVQKFAYCHAHTP--------------------ADAKLKMN---------------------VPDFEDTRHKMKEARKALAKKRS----------TAPVVLIPTIPPDRVQEIATMVTMQRKKEFLDRIIAYWTLKRHYRNGVPLLRRLQSQGNNHGVIQRNGIEGSPDTGELYRQLKYWQCLRQDLERARLLCELVRKREKLKVAFVRISEEVVMLQLNPLEAALNKLLDALEARDSMQIFREPVDTSEVPDYTDIVKQPMDLGTMRAKLKECQYNSLEQLEADFDLMIQNCLAYNNKDTVFYRAGIRMRDQAAPLFVQVRKELQRDGLLARSQRYHVDHVEAEVEQELRLLLAAPASEGIVQKLLILADKSQVLKNPTYRTKKIKQIRLEISRMRKSLQKARFAARHSSHANQSQSDDEDTLGGSPSKKRTRKRFNSSGVDMELGHDDDDEEEDSDEDSMGEDTVSKDLLNSTQTPPCSPIKSLNNSSSPVGINRRTAILLTRKAQAALKRPSEPLTTPVKEEQHNSQSSNTQSTSGSSSSVTTAATAASSGAGTLNHVLSSAPPTASSFALTQNNSSGGGALASGTGIGGSSSAGTAAAASLTSTALAMNSKLSANLPVKSPKRPGRYRRVPEVRHSSSMSPKKSPNPAVTVSQALPMPETLPFERIPDSFRVYRANNQRDVSDSDDAPSQSSSPCSSCSDFSMSGSCSDFDSDEASEGDADGDPDRDGGRSRSEERDSTSQEGTTDAMDMQHASLNNVQGNNGNMAISSSSGGSGGSSSEDDELEERPLSARQNKPMKVGTRGTPTPTTMARAVALSAGRGRGKRRSNLSESTSSTATPPPLRRAGKLRSATPNASPLVNNIKARRNTTAAGSAPLTNNNRSKHSEDSASSERHNNHSHGQKPALEPLQLVWAKCRGYPWYPALILDPKTP-KGFVYNGVPLPAPPTDVLALRKN---CLDEIVFLVLFFDVKRTWQWLPANKLDILGIDKQLDQQKLVESRKPAERKAVKKAYQDALHYQSQVSDLEGQGPDPIM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12311-1", "uniprot_id": "NTO1_YEAST", "id": "Q12311-1", "name": "NuA3 HAT complex component NTO1", "aln": "-----------------------------------------------------------------MNRGSLDDGPKLREEKHFQDFYPDLNADTLLPFIVPLVETK---------------DNSTDTDSDDISNRNNREIGSVKSVQTKELIFKGRVTTEPLVLKKNEVEFQKCKITTNELKGKKNPYCVRFNESFISRYYHINKVRNRKSYKQQQKEFDG-----------------------------VEAPYFTKFSSKEAPNITISTSTKSAIQKFASISPNLVNFKPQYDMDEQDELYLHYLNKRYFKD---QMSHEIFEILMTTLETEWFHIEKHIPSTNSLIARHNILRDCKNYELYGSDDGTGLSMDQACAVCLGTDSDNLNTIVFCDGCDIAVHQECYGIIFIPEGKWLCRRCMISKNNFATCLMCPSHTGAFKQTDTGSWVHNICALWLPELYFSNLHYMEPIEGVQNVSVSRWKLNCYICKKK-MGACIQCFQRNCFTAYHVTCARRAGLYMSKGKCTIQELASNQFSQKYSVESFCHKHAP----------------------RGWQTSIEGINKAR------------KYFSLLSTLQTETPQHNEANDRTNSKFNKTIWKTPNQTPVAPHVFAEILQKVVDFFGLANPPAGAFDICKYWSMKRELTGGTPLTACFENNSLGSLTEEQVQTR-----------IDFANDQLEDLYRLKELTTLVKKRTQASNSLSRSRKKVFDIVKSPQKYLLKINVLDIFIK------------SEQFKALERLVTEPKLLVILEKCKHCDFDTVQIFKEEIMHFFEVLETLPGASRILQTVSSKAKEQVT----------------------------------------------------------------------------------------------------------------------------------------------------------NLIGLIEHVDIK------------------KLLSRDFIINDDKIEERPWSGPVIMEEE-GLSDAEELSAGEHRMLKLILNSG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : : : . . : : ::.: : . . : . . . :.. * :: . . : :: : :**:**:* :*. :*:. : : :*:*: ** * :. * *.:**. :. * *.*:*** *::****:***: :****:**** *: * .. . *::**. ******. * *.* :**:*:**: *:* ::**::.:..:. :**:*.**:**:* **.***.: .*: *:*****::***:*. .::: * ::*. *:* . : : . .: * : . :::: . . . : ** :**. .*.** :..: :: :.: : .** : : * *::** : . : : .. : * *. : : : .* . : : .: .: * : : :: :: :: :. . :: .. : :: :*: . :* * : . . : ", "identical_positions": 111, "similar_positions": 187, "identity": "7.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-731", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NHY0-1", "uniprot_id": "B4GN2_HUMAN", "id": "Q8NHY0-1", "name": "N-acetylneuraminylgalactosylglucosyl-glucoside beta-1,4-N- acetylgalactosaminyltransferase 2", "aln": "MGSAGFSVGKFHVEVASRGRECVSGTPECGNRLGSAGFGALCLELRGADPAWGPFAAHGRSRRQGSRFLWLLKILVIILVLGIVGFMFGSMFLQAVFSSPKPELPSPAPGVQKLKLLPEERLRNLFSYDGIWLFPKNQCKCEANKEQGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRPLPLLVQPNLPFGYPVHGVEVMPLHTVPIPGLQFEGPDAPVYEVTLTASLGTLNTLADVPDSVVQGRGQKQLIISTSDRKLLKFILQHVTYTSTGYQHQKVDIVSLESRSSVAKFPVTIRHPVIPKLYDPGPERKLRNLVTIATKTFLRPHKLMIMLRSIREYYPDLTVIVADDSQKPLEIKDNHVEYYTMPFGKGWFAGRNLAISQVTTKYVLWVDDDFLFNEETKIEVLVDVLEKT-ELDVVGGSVLGNVFQFKLLLEQ--SENGACLHKRMG-FFQPLDGFPSCVVTSGVVNFFLAHTERLQRVGFDPRLQRVAHSEFFIDGLGTLLVGSCPEVIIGHQSRSPVVDSELAALEKTYNTYRSNTLTRVQFKLALHYFKNHLQCAA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q09199-1", "uniprot_id": "B4GN2_MOUSE", "id": "Q09199-1", "name": "Beta-1,4 N-acetylgalactosaminyltransferase 2", "aln": "MTSS--------VSFAS------------------------------------------------FRFPWLLKTFVLMVGLATVAFMVRKVSLTTDFSTFKPKFPEPARVDPVLKLLPEEHLRKLFTYSDIWLFPKNQCDCNSGKLRMKYKFQDAYNQKDLPAVNARRQAEFEHFQRREGLPRPPPLLAPPNLPFGYPVHGVEVMPLHTILIPGLQYEGPDAPVYEVILKASLGTLNTLADVPDDEVQGRGQRQLTISTRHRKVLNFILQHVTYTSTEYYLHKVDTVSMEYESSVAKFPVTIKQQTVPKLYDPGPERKIRNLVTIATKTFLRPHKLKILLQSIRKYYPDITVIVADDSKEPLEINDDYVEYYTMPFGKGWFAGRNLAISQVTTKYVLWVDDDFLFSDKTKIEVLVDVLEKT-ELDVVGGSVQGNTYQFRLLYEQ--TKNGSCLHQRWG-SFQALDGFPGCTLTSGVVNFFLAHTEQLRRVGFDPILQRVAHGEFFIDGLGRLLVGSCPGVIINHQVRTPPKDPKLAALEKTYDKYRANTNSVIQFKVALQYFKNHLYCST-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58J1W0-1", "uniprot_id": "A0AC58J1W0_DANRE", "id": "A0AC58J1W0-1", "name": "", "aln": "MKKGQGCTKHTILDKPIYVHVCILINGQGPVR---------------------------LQDLEGFRSSFIMNCKHHLLLKGFL-LLLAICFIQLGIMSVKKDIIASSSGPQPGKVFAKPHIETFLYTN------RLSCSLEDAVLT-----RQHVPQNELEDIVKRRAEEYRQHQIRMEADIASLILAPANSPLQYPITGFTISPLKKSIVPGLALHAQQRKVYKVSLSVMSGVLS-VEDVQDEQVEGQGQSELIISSSNLTQLNDLLSRVSYTSTVYHIKTSDLVIFSFEDHLAMFPITIKRQSVPVLFDPGND--INSQVTIITKTFLRYEELNILLNSIRKFYPKIKILIADDSIQPRTVSGDNIEHYIMPPAKGWFAGRNLALSQVETKYFLWVDDDFVFLKDTRIESFVEIMEAVPELDILGGSVIGDPPYFILEYDEGDEEEGGCLSRIYNQFHQPLPGFDDCVLVDGVVNYFLARTDAVRRVGFDPFLKRVAHSEFFMDGLGQLLVASCERFTIGHQGHR---------FEKKYSHYRTQTDADKRKKLSHHFFKNYLKYVKF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .. :. . * :::: :: . : ::. : : : * .: .: *::.: ::..:: . : .*. : :: *.:* : ** *:.:.* * . :*. .* *: **: *. : **:. :*** .. : **:* *.. *.*. : ** *. *:*:** :* **: . . *: :*.:*:**** * :. * * :. .. :* **:**:: :* *:*** : :.. *** ****** .:* *:*.***::**.:.:::**** :* :..: :*:* ** .**********:*** ***.*******:* ..*:** :*:::* . ***::**** *: * * :: ::*.** : . .*.* ** .*.:..****:***:*: ::****** *:****.***:**** ***.** . *.** : :**.*. **::* : : *:: ::***:* ", "identical_positions": 177, "similar_positions": 167, "identity": "31.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-738", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q69Z37-1", "uniprot_id": "SAM9L_MOUSE", "id": "Q69Z37-1", "name": "Sterile alpha motif domain-containing protein 9-like", "aln": "MSGQVTQPKLIKDWTKEHVRKWVTEDLNIVEKYAQILFKEEVTGMVLQELTEEDLR-EMGLPRGPALLIKRMYNKLIS-SPESHNQDSRELNDKKLSTKEQQ---TKTKNEEENSVSSNSDHGLRETGQNEEQEPSLTKENMLGDVV-TKDMEDNKPKPEQMSCTPYPFDSFCDVKQYIEHSILRVAETGPLNLIDPIHEFKAFTNTKKATEEDIKMKFSNETFRFAAACMNSRTNGTIHFGVKDKP------HGEIVGVQVTSKDIFVNHFNTMITKYFEDSEISEARACIREPRFVEVLLQNNTQSNRFVIEVDVIPRHSICQEKYFYIMMQSSTGKTWKQSKDTSLFVREGASSKNILGNPNQRDREFKKFLEDLKMWTASRKAAEEELRMVTKK--ESEGLKLSKLLTRHQGSLDESYYDWYILVTNTCAPTQLEHLEFIKEMKLFAVLDFDPYSHIKGVVKAYRESRIANLHLPSHYEEKTT--IAEKISTLKLYEQPSWIFCNGRVDLS---CQPLEPHLWQRDRASGVRRLISFLTDENIIVKGKVLVVFLLLSPIENQKDPLIETFCAFYQVFNGMDNMLCICVNSAIYQQWSDLLQVRLEIKDDLAKHSISTLNIELVNNTILKLKSVIQSSRRFLPSCGSSSVILEKMDEDIMSALEILCENECKDTDIEKDESQFLEFKKSREEHFYRGGRVSWWNFYFSSENYSSAFVKRDSFEELTTLIQQCADSP-KPVFVKVINLYHHPGCGGTTLAMHVLWDLKQKFRCAVLKNKATDFVEIGEQVSKLMSYKATSHEDFIPVLLLVDDFEEQENAYILQNAINAFIAEKGLRYEKTLVIILNCMRSQNPDESAKLAN--SISLKYQLSPKEQRAFEAKLQEIEKEHKNCENFYSFMILKGNFD----TTYIKNVVKNTLKDLDAKSRRAQLISYLALLNSYVTDSTISVSQCEIFLGITYTKKYGKPETVEKNMGTYSTLLIRTEVSDYGRYTGIRIIHPLIATHCLKELEMSYRMDKCQIALNMLEENVLYDSGLGRDKFKYDVQTLLLTRQRKEHGAETDTLFSPLIEELQNE----ETEKVLIAGSDRFPQNAFICQALARHFYIKEKNFSTALVWANLAKRKAPKNSYISDTLGQVYKSELN---SG---------------WEVAEKASKAFKESQNQSDSKDYGTEAWSPQNSQRRYDTFNTAGFFGEIEVGLDTIQLLQLTPLFHKENEISKESMAEFLSGKGTILSDPKGEYCVVLSKFTSLLQNLHSDLERCFHFFGDYMGFLKPRNTPKELTELLLSKKVSRCFKKYVELFCHLDTNLVQGKEDLLLQKENCRKRIQAWRADTFSGLLEYLNPNHKEANNIENIVGNYTFLLQDILNKQLSKVLTKDIQNFILANIILSCLKPSSKYILPFSTLKKKLREVLQIVGLTHSYPDPYFLACLLFWPENKELDEDSTLIEKYVSSLNRSFRRQYKHMCRSRQPS-----TLFYLGQKKGLNSLVHKAEIERYFSEVQDSNS--FWHSGVVWEKREVKDLLRLLDGQAEGKLISLEYGTEAKIKIPVTSVYSAPLRSGRNIERVSFYLGFSIEGPLAYGIKVI---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IVG5-1", "uniprot_id": "SAM9L_HUMAN", "id": "Q8IVG5-1", "name": "Sterile alpha motif domain-containing protein 9-like", "aln": "MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLV-EMGLPWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNIDYDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEHYTLQP-ETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFGVKDKP------HGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPSDRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRDVDFKAFLQNLKSLVASRKEAEEEYGMKAMKK-ESEGLKLVKLLIGNRDSLDNSYYDWYILVTNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTN-MWEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTRGKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKMEDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILCENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKDLIHCWAESP-KPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQVINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCMRSRNPDESAKLAD--SIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFD----ETYIENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESLEDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENLFYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNK----DIEKVLSAGSRRFPQNAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKNCRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGEIEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNLQSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKESQLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQ----QNSKKPMTNEKQNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQELDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQAS-----TLFYLGKRKGLNSIVHKAKIEQYFDKAQNTNS--LWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGRNIERVSFYLGFSIEGPLAYDIEVI---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q795-1", "uniprot_id": "F1Q795_DANRE", "id": "F1Q795-1", "name": "", "aln": "--MEKPEDSPMETWTESMVSNWLKS-IGIKEAYIEKLHEEEVNGQVLSKVSEEFLKKETGMKAGPALLIIKERNEILKNSQKAQSKP------------------KQPSGKNENGVSKN------KVADTRADIKEVDEEDPVPAVLRNRDTK------------PRPFEMKGGDFKYVKNSVLLP-ESGVIDMISPCHEYKSFAIAATLDRQRLQAKLAREVLKFATGCMNVRTNGTIHFGVMDSRGDAGHVHGEIVGFPVKEKDIYYDALDYIEKG-FSESDSELVRLCIGEPQFVQVICSDSSE-EHFIVEVDIKPSVRIVKNQVFSVRLPNFSEEANKVQLEKKTVYRR-------VGSKTEPVADLMEFYQHVSLRDSQREEAEKMQKFTSPEPSQNLGKKLTMLITGGKKVMDK--DKWHILVTNRFQEKDLQSIDFLLNMKIFCVFDFDPDSNVTGLCREYDKHHAVNRHFMQNYKIPSGLSIREFESRERLFDQISWIFCNGRSDFKG-SEPHCDEKTWVKTKRTLLKECVSLICKN-ILPKGTFQVIFLLTSPVDT---PLLNTFYEFITDMEGHEDIICLAESEENFKKWQSFALGSSDMET-IKQSSVVGMTVSQINATLQRVQPTTTQATKRLPILVKGECFLDTREEKVRSSLEILSLNHCEENSPDVIES----EKETIEKQFYHGGKVTWINLWLAEKKIVGEVIQRDAYNEVNELVKECLNWSSERAPISCINIYHHPGSGGSTVARQVLWNYRRDLRCAVVK-SSKSVSAVSEDAVWLREYEEKDPQKCLPLLLLFEDCD-QEYLEDVKYELEVAVNTKKITRGTLCFILLSCRRSHNPEKMCKESPQHNVAITHKLSEKEKQHFSKKRHSLEKQFK-PEFILTFVLMSEEFKSHKIAEYVKQFVKHLLQGIDHNSAVTKLVLYVALLNTYVQNSFLSRSHCEALLALSILVDRFRQHVFETSLSEQARLVLIHLRDENTYITSIRIIHPLVAKEILHQLLG-DEQQQSDLALDLLNNDVLFEHRFGKDHYMKFLRDLFMTRHRISKGDESDSFFSPLIEHVRKKECPDKAIDLLKGAYKRFNEDAFFAQHLARLNYKHER-FEAAEQWAKTAVAKMPHNSYILDTKGQVYRQWFLAKCKA-----------------IKQNETPENTVDPLEMAFKAIECFQACENAAVQDNDTMNNAGFVGVVEVGCALLKLMSNLQVFSRRRRPSELSRYLLTNYIPPEIETPWENFHYKLKNLQKTMLEALEWISEDLSFFQTDLNTDEEK--TAETVESTIKHPIHWLVNKSHDYGRYFSGASPGTDKNREKLSPVMKRMMIHYHGGGNITTILFLLTNQKDRDPVPVLEKIISFYPSD---PMRAQLPQVDLVNYIASHLALSLLSPESPKLAAFQDLQRMSYQFLK-EGQKKSISNANFLLVLLFWPEEQETEVEKERKYKIVLSAVENLQRDYEKRLKDIPPRKKRIYTHFFLSNGTGFEKFVHKSKFETITKLFSVPEKRLKWFSGEVWKMPEMSKLLKCVTGWTEDEKVYLEGPKGMKFHIPALKMSSIPHKN----ENVTFYLGFTLKGPVAYNITVQTQN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . :: **:. * :*:.. : * * * : * .***.* **.:::*: * * *: ****** : *:: . * ::..: .:.. ::**.:*.* : : . : : :*: : * :. : * **: . :*::: * *:* :::*.* **:*::: : . . :: *::.*.::**:.*** ********** *. ******. :..* : : :: : . *.:*: . .: ** **:**:*: .:.: ::*::*** * * ::: * : : . : * . : . . *. :.. .: :: * :.:. :.*: **: : : : :. * ** *: : :*: .*:***** .::: ::*: ::* *.*::*** * :.*: : * : : .* *: .:*: : : * * .*::* ******** *:. : : * : : : ::. : :: .: *: :*.. *:*** *.::. **::** * ::* ::::*:. .. :::*..: .:: : : *: :.:. :* *: :::.. .: : ** ... :*:. .*.: ::****. *.* :.. : :* *:: *::**:**:*:* *::::.:: . .::**:::::. *:: : . : . **:*****.**:*:* :***: ::.:****:* .:... :.*:. * *. .. :. :*:***.:* : ** :: :. : * : . .*:*.* **:**:: .* : .:::.::** **:: * * :.:**:.* * : :*:::. :*. *:::.*:: *:. * .* ::*: ::***.:** :* :* *:** :*.: . . .* .:. : *:: : *.:******:* *::* . ::.::**::*::::::: :*:*:: :: *::**:* * *:*::****:* :::: . .:* .. ** ::**:.* *** * :*: *.:* **. * * *:**** ** ****:. : .. :: : . . : * . : : : * *.* *.* :*** ::::. .* :... *: : . . * : *.:: . : : . :.. : ** : : : * .* :.: : ..* : ::. .:. . :: : :.. : :* .* *: : : :* . : : * * ::: ** *.*.* : .: *:: :.*: * .:. ... ** ******::* : :. * * * ..:: :*:: :. . * *:*.: .*::.:***:::* . . .:. *.** **: *:..**: : * :*.: : :* . *::**. .: * * :. *.*:*****:::**:**.* * ", "identical_positions": 376, "similar_positions": 588, "identity": "23.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-741", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TSJ2-1", "uniprot_id": "MAP6_MOUSE", "id": "Q7TSJ2-1", "name": "Microtubule-associated protein 6", "aln": "MAWPCITRACCIARFWNQLDKADIAVPLVFTKYSEATEHPGAPPQPPAP---LQPALAPP-SRAVAIETQPAQ-GESDAVARATGPAPGPSVDRETVAAPGRSGLGLGAASASTSGSGPADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQIPATSQPSQPVLGVPKRRPQSQERGPMQLSADARDPEGAGGAGVLAAGKASGVDQRDTRRKAGPAWMVTRNEGHEEKPLPPAQSQTQEGGPAAGKASGADQRDTRRKAGPAWMVTRSEGHEEKPLPPAQSQTQEGGPAAGKASGADQRDTRRKAGPAWMVTRTEGHEETPLPPAQSQTQEGGPAAGKASGADERDTRRKAGPAWMVRRSEGHEQTPAAHAQGTGPEGGKGRAVADALNRQIREEVASTVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPD-DKMVHETSYSAQFKGEANKPSAADNKAMDRRRIRSLYSEPFKECPKVEKPSVQSSKPKKTSTSHKPPRKAKDKQVVSGQAAKKKTTEGPSATKPDD--KEQSKEMNNKLAEAKESRVKPTSDASKNRGPVTKEPHKDQGSVAPGLPKGQ-----EPLKDQGPVVPGLPKDQVPVVPGSLKGQSPTAPGPTKDQGAVLLGPVKDLGPVAPAPIKVQDHIASELLKNKDSVPLAPAKAQSPLLPEPLKNQSPVVPASTKDQ---------------SFPT------------------PAPRKDPGPVIPEPEKDRAPTVPERRKDQHVSIMASLKNEAPMVPESVKNQGLAGPELVKDTGTDTTAPRYLKGHDSVFVAPVKNQGPVIPEPVKSQDPIIPALAKDQGPMLPEPPKNQSPVVLGPIKNQDPIIPVPLKGQDPLVPAPTKDQGPTAPDPLKTQGPKGTQLPTVSPSPPVMIPTVPHTEYIEGSP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JE9-1", "uniprot_id": "MAP6_HUMAN", "id": "Q96JE9-1", "name": "Microtubule-associated protein 6", "aln": "MAWPCITRACCIARFWNQLDKADIAVPLVFTKYSEATEHPGAPPQPPPPQQQAQPALAPPSARAVAIETQPAQ-GELDAVARATGPAPGPTGEREPAAGPGRSGPGPGLGSGSTSG--PADSVMRQDYRAWKVQRPEPSCRPRSEYQPSDAPFERETQYQKDFRAWPLPRRGDHPWIPKPVQISAASQASAPILGAPKRRPQSQERWPVQAAAEAREQEAAPGG---------------------------------------------AGGLAAGKASGADERDTRRKAGPAWIVRRAEG--------------------------------------------LGHEQTPLPAAQAQVQ------------------------------------------ATGPEAGRGRAAADALNRQIREEVASAVSSSYRNEFRAWTDIKPVKPIKAKPQYKPPD-DKMVHETSYSAQFKGEASKPTTADNKVIDRRRIRSLYSEPFKEPPKVEKPSVQSSKPKKTSASHKPTRKAKDKQAVSGQAAKKKSAEGPSTTKPDD--KEQSKEMNNKLAEAKESLAQPVSDSSKTQGPVATEPDKDQGSVVPGLLKGQGPMVQEPLKKQGSVVPGPPKDLGPMIPLPVKDQDHTVPEPLKNESPVISAPVKDQGPSVPVPPKNQSPMVPAKVKDQGSVVPESLKDQGPRIPEPVKNQAPMVPAPVKDEGPMVSASVKDQGPMVSAPVKDQGPIVPAPVKGEGPIVPAPVKDEGPMVSAPIKDQDPMVPEHPKDESAMATAPIKNQGSMVSEPVKNQGLVVSGPVKDQ--DVVVPEHAKVHDSAVVAPVKNQGPVVPESVKNQDPILPVLVKDQGPTVLQPPKNQGRIVPEPLKNQVPIVPVPLKDQDPLVPVPAKDQGPAVPEPLKTQGPRDPQLPTVSPLPRVMIPTAPHTEYIESSP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FFM0-1", "uniprot_id": "E7FFM0_DANRE", "id": "E7FFM0-1", "name": "", "aln": "MAWPCITRACCINRFWSELDKGDIAVPLVFTKYSDVAEVQHLHPQP-------KPVLSQK---PVATESHLAHSAHQEASSRAT------HGAADAAAAASQDGSG--------------ASVMREDFKAWSVR-PERSCKPRNQYQPSKTPFINETQYQKDYKPWPIPKKGDHPWIPKPTAAAAPCKAES------KFSKHEQAAAEMETGVEKCEIE--------------------------------------------------------EKQHEKESKERRKKVE---------------------------------------------------------KKEPVSEASKMEK------------------------------------------DVAVE-GKRRSAADALNRQIKQEVTS--GSSYRTEFKAYRDIKPVKPIKAKSQYKLLVGEKTNLETSYSATFKGEQAKPQTTDNKLMEHRRIRSLYSEPSKESSKVERHNLSLTKPKKTPSHSKTVKKAKEKPVAGSQPAKKKTSVSNQEPKPEGGVTKKSKEMINRLAEAKD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************ ***.:***.************:.:* *** :*.*: .** *:: *: .. :* :*** :..*...:.* * ****:*::**.*: ** **:**.:****.:** .*******::.**:*::*********. .*..:.. * :.* :: ..: : * * :.:: *:*. :: *:. *. : .. * *: *:.********::**:* .****.**:*: ***********.*** :* ****** **** ** ::*** :::********** ** .***: .:. :*****.: *. :***:* ....*.****:: . . .**:. .::**** *:*****: ", "identical_positions": 188, "similar_positions": 116, "identity": "19.75%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-744", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9H8-1", "uniprot_id": "D4A9H8_RAT", "id": "D4A9H8-1", "name": "Serine/threonine-protein kinase NIM1", "aln": "MTAVVVNGGGLVNTHCDRWDRRDSAEGSCQTEGSKDGEEDQPRQLTPFEKLTQDMCQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKI--LDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSSTCVKVGDFGFST--VSKKGEMLNTFCGSPPYAAPELFRDEHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGAYSIPQHVSEPCHRLIRGVLQPTPAERYGINYIMSNEWMRG------------------------------------------------------------------------------VPYPSPLE--------------------------PFQLDP-KHLSETS-------------------------------------------TLKEEENEVKSTLEHLGITDEHIRNNQGRDARSSITGVYRIILHRVQRRKALESVPMATLPEPKDKDLKKGSRVYRGIRHTSKFCSIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BHI9-1", "uniprot_id": "NIM1_MOUSE", "id": "Q8BHI9-1", "name": "Serine/threonine-protein kinase NIM1", "aln": "MTAVFVNGGGLVNTHCDRWERRDSVESSCQTEGGKDSEEDQQRQLTPFEKLTQDMCQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKI--LDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFST--VSKKGEMLNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYTIPQHVSEPCHRLIRGVLQPTPTERYGINYIMSNEWMRG------------------------------------------------------------------------------VPYPTPLE--------------------------PFQLDP-KHLSETS-------------------------------------------TLKEEENEVKSTLEHLGITDEHIRNNQGRDARSSITGVYRIILHRVQRRKALESVPIMILPEPKERDLKKGSRIYRGIRHTSKFCSIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IY84-1", "uniprot_id": "NIM1_HUMAN", "id": "Q8IY84-1", "name": "Serine/threonine-protein kinase NIM1", "aln": "MTAVYMNGGGLVNPHYARWDRRDSVESGCQTESSKEGEEGQPRQLTPFEKLTQDMSQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKI--LDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFST--VSKKGEMLNTFCGSPPYAAPELFRDEHYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIPTERYGIDCIMNDEWMQG------------------------------------------------------------------------------VPYPTPLE--------------------------PFQLDP-KHLSETS-------------------------------------------TLKEEENEVKSTLEHLGITEEHIRNNQGRDARSSITGVYRIILHRVQRKKALESVPVMMLPDPKERDLKKGSRVYRGIRHTSKFCSIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7I0-1", "uniprot_id": "A0ACD6B7I0_DANRE", "id": "A0ACD6B7I0-1", "name": "Serine/threonine-protein kinase NIM1", "aln": "MTAVYPAVGVSVGVSSVGPQRYARWSRQDSSDICTDDEGTQARRLTPLEKLNLDMCQDEKMVRELTVGRRIGFYKIRGEIGCGNFSHVKLGIHALTKDKVAIKI--LDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLTRLHLVMEYAGGGELYTKISTEGKLSDIDSKIVFSQVLSAVKHMHDNNIIHRDMKAENVFYTCSTCVKVGDFGFST--VSRRDETLNTFCGSPPYAAPELFRDEHYIGVCVDIWALGVMLFFMVTGTMPFRAETVAKLKRCILDGTYTVPTWVPEPCQKLIRGILQPQPSDRCSVEQMMACEWLQP------------------------------------------------------------------------------VEFPKAME--------------------------PFKLDP-HHLVESGP-----------------------------------------GELEEHEIEVRNALEMFGITAEHIRNNQGKDCRSSITGVYRILLHRAHKRQAVESMPVVTHVVNGTDAKKERLKTYRSLRHTSKLCIIL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPW3-1", "uniprot_id": "Q9VPW3_DROME", "id": "Q9VPW3-1", "name": "non-specific serine/threonine protein kinase", "aln": "-----MRSSATVKVTSAATPPHPPPLTTTTTPLTICQ---PPPPTPPYQRLTKALQCDPRCGHEVTIGRRIGLYRFCGDIGRGNFSKVKLAVHQLTRDKVAIKVVDLDRAGLDAKALRMLSSEIATLECVHHPNILRLFEVVETLGRVYLVTEWIRGGELYNHITQGGPLREIHAAPLLKQLLLAVKHMHSLGYVHRDIKAENVLLLSEDRLKLADFGFSTQLINGANQKLDTFCGSPPYAAPELFSDDHYIGAPVDVWALGILLYFMVVGNMPFRAPTIPGLKAAILKGDYLLPGQLSLPCIRLIQRILIHIPAQRPTIDDMLNSQFVTCPKLSADLMQWEINQHTKPVKRSIFWVRSKSHRLRKSASLRDRYAEVVKKPAISMNTRQQDEMFVQNFLQPIEMGHELLVPVSSQLKEPQSTEQAKRPTRRYMFCGSLKKKVTPMETEPEKQLANGGQSIGSAKINPWNVEVAEDCPLFKNYDAETGSCVMLPTNTEDLSQLGALEFEARQILAELGLTSEMLINARQSGPRSDIIGAYRIVVNRLQKQSWLARKHVEMALHSEPKVEKR----------IERSCCIL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : .* ::*. : * : :*:*:*:***:*:: *:** ****:***.:* **::*****: **:: ** *: *:** **:::* :*****:**:****** :::** *: ****: :*: * * : .: ::.*:: ******. :***:*****: . :*:.****** :. .: *:************** *:**:* **:****::*:***.*.***** *:. ** .**.* * :* :. ** :**: :* *::* :: :: ::: * .. :: *:: :* ::* : . * * *.:. * :*:* * : * : . **.* *.***:::* :::. : : *. .: * **", "identical_positions": 159, "similar_positions": 120, "identity": "27.04%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-750", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IXL6-1", "uniprot_id": "FA20C_HUMAN", "id": "Q8IXL6-1", "name": "Extracellular serine/threonine protein kinase FAM20C", "aln": "MKMMLVRRFRVLILMVFLVACALHIALDLLPRLERRGARPS----GEPGCSCAQPAAEVAAPGWAQVRGRPGEPPAASSAAGDAGWPNKHTLRILQDFSSDPSSNLSSHSLEKLPPAAEPAERALRGRDPGALRPHDPAHRPLLRDPGPRRSESPPGPGGDASLLARLFEHPLYRVAVPPLTEEDVLFNVNSDTRLSPKAAENPDWPHAG-AEGAEFLSPGEAAVDSYPNWLKFHIGINRYELYSRHNPAIEALLHDLSSQRITSVAMKSGGTQLKLIMTFQNYGQALFKPMKQTREQETPPDFFYFSDYERHNAEIAAFHLDRILDFRRVPPVAGRMVNMTKEIRDVTRDKKLWRTFFISPANNICFYGECSYYCSTEHALCGKPDQIEGSLAAFLPDLSLAKRKTWRNPWRRSYHKRKKAEWEVDPDYCEEVKQTPPYDSSHRILDVMDMTIFDFLMGNMDRHHYETFEKFGNETFIIHLDNGRGFGKYSHDELSILVPLQQCCRIRKSTYLRLQLLAKEEYKLSLLMAESLRGDQVAPVLYQPHLEALDRRLRVVLKAVRDCVERNGLHSVVDDDLDTEHRAASAR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5MJS3-1", "uniprot_id": "FA20C_MOUSE", "id": "Q5MJS3-1", "name": "Extracellular serine/threonine protein kinase FAM20C", "aln": "MKMILVRRFRVLILVVFLLACALHIAVDLLPKLDRRATRSS----GEPGCSCAQPAAEAAGPGWAQARSRPGE-----SAGGDAGWPNKHTLRILQDFSSDPASNLTSHSLEKLPSAAEPVDHAPRGQEPRSPPPRDPAHRPLLRDPGPRPRVPPPGPSGDGSLLAKLFEHPLYQGAVPPLTEDDVLFNVNSDIRFNPKAAENPDWPHEG-AEGAEFLPTGEAAVNLYPNWLKFHIGINRYELYSRHNPAIDALLRDLGSQKITSVAMKSGGTQLKLIMTFQNYGQALFKPMKQTREQETPPDFFYFSDYERHNAEIAAFHLDRILDFRRVPPVAGRMINMTKEIRDVTRDKKLWRTFFVSPANNICFYGECSYYCSTEHALCGRPDQIEGSLAAFLPDLSLAKRKTWRNPWRRSYHKRKKAEWEVDPDYCEEVKQTPPYDSGHRILDIMDMTVFDFLMGNMDRHHYETFEKFGNETFIIHLDNGRGFGKYSHDELSILAPLHQCCRIRRSTYLRLQLLAKEEHKLSLLMAESLQHDKVAPVLYQLHLEALDRRLRIVLQAVRDCVEKDGLSSVVEDDLATEHRASTER", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3B8M1-1", "uniprot_id": "A0A8M3B8M1_DANRE", "id": "A0A8M3B8M1-1", "name": "", "aln": "--MILFRKFRVLILTVFLIACTMHIMIDLLPKLEKRAAGSSSSAGGGSGCSCAHTPGEEPRS-WGKQR----------ARAADPGWPNKHSLRLLQDFSNEPNSNLTSQSREKVTERAGSEKQG-------------SGKRGLMREADSRQRRTDVRVS---SVLQSLFEHPLYRTVLPDLTEEDTLFNLNAEIRLYPKAAGQQEWHNEGNVEEEEFSPPGEANSESYPNWLRFHIGINRYELYSRHNPVIAALLRDLLSQKISSVGMKSGGTQLKLIMSFQNYGQALFKPMKQTREQETPPDFFYFSDFERHNAEIAAFHLDRILDFRRVPPVAGRLVNMTREIRDVTRDKKLWRTFFVSPANNICFYGECSYYCSTEHALCGKPDQIEGSLAAFLPDLALAKRKTWRNPWRRSYHKRKKAEWEVDPDYCDEVKQTPPYDRGTRLLDIMDMTIFDFLMGNMDRHHYETFEKFGNDTFIIHLDNGRGFGKHSHDEMSILVPLTQCCRVKRSTYLRLQLLAKEEYKLSSLMEESLLQDRLVPVLIKPHLEALDRRLRLVLKVLSDCVEKDGFSAVVENDLDGQPSVHGGR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A4VCL2-2", "uniprot_id": "FA20C_DROME", "id": "A4VCL2-2", "name": "Extracellular serine/threonine protein CG31145", "aln": "--MAVLRTMKLKERLVISLGATLVLLTLLLIVDVQMDFGVA-------NRHLLQQQHQKIRLGNDYDG-----------GTGGGGMLHEFKRKFLQKSNASGSKEASTQAGASQSGGATSGQDA---------------------AAGASGGAAGPGTS----------RSTSTRKPTPHDRYADLQKHLLSDEYSHVIVDNAPDVSRDNPTLAEMLHRKASANAS---NLERFQLRITKKELYGEQDTLVDAVLRDMIKLPIQHVVQKEGGTQLKLIIEYPNDIKALMKPMRFPREQQTLPNHFYFTDYERHNAEIAAFHLDRILGFRRAMPVAGRTLNITTEIYQLAEEN-LLKTFFVSPSLNLCFHGKCSYYCDTSHAICGNPDMLEGSFAAFLPNFESGNRKLWRHPWRRSYHKRKKAQWETDANYCALVRDIPPYDDGRRLYDLMDMAVFDFLTGNMDRHHYETFKVYGNETFPLHLDHGRGFGRPFHDELSILAPVLQCCLIRKSTLVKLLDFHNGPKPLSQLMSESLSQDPVSPVLWQPHLEALDRRTGIILQSIRDCIKRN-----PPGDVDGSETDVSS-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :.* ::: *: :..:: : ** : : . : : .. * ::.. ::**. . . .: :::: . . * . . . ... . . . . : * * :: :: . : . . . : ..* . * :*:: *.: ***..::. : *:*:*: . * * *.********: : * :**:***: .***:* *:.***:*:****************.***. ***** :*:* ** :::.:: * :***:**: *:**:*:*****.*.**:**.** :***:*****:: .:** **:************:**.*.:** *:: **** . *: *:***::**** ***********: :**:** :***:*****: ***:***.*: *** :::** ::* : : ** ** *** * : *** : ******** ::*: : **:::: .*: . ", "identical_positions": 199, "similar_positions": 154, "identity": "33.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-754", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BVW0-1", "uniprot_id": "GANC_MOUSE", "id": "Q8BVW0-1", "name": "Neutral alpha-glucosidase C", "aln": "-----MEAAEKEEISVEDEAVDKTIFKDCGKIAFYRRQKQQLTKTTTYQALLGSVDTEQDSTR--------------FQIISEATKIPLVAEVYGIEKDIFRLKINEETPLKP----------------------------------------------------RLVCS-GDTGSLILTNRKGDLKCHVSANPFKIDLLSKNEAVISINSLGQLYFEHLQVPHKQRATKGNGQNTPAATSQENQEDLGLWEEKFG-KFVDVKANGPSSVGLDFSLHGFEHLYGIPQHAESHQLKNTRDG-DAYRLYNLDVYGYQVHDKMGIYGSVPYLLAHKQGRTVGIFWLNASETLVEINTEPAVEYTLTQMGPAAAKPKVRCRTDVHWMSESGIIDVFLLTGPTPADVFKQYSYITG------------------TQAMPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDVMWLDIEHTEDKKYFTWDKKRFANPKRMQELLRSKKRKLVVISDPHIKVDPDYTVYAQAKEQGFFVKNPEGGDFEGVCWPGLSSYLDFTNPK-VREWYSSLFAFPVYQGSTDILFLWNDMNEPSVFRGPELTMHKSAVHYGDWEHRELHNIYGFYQQMATAEGLIQRSKGKE-RPFVLSRSFFAGSQKYGAVWTGDNKAEWSYLKISIPMLLTLSVSGISFCGADVGGFIGNPEAELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGEEYTQLIREAIRQRYALLPYLYSLFYHTHVSSQPVMRPLWVEYPDDLETFAVEDEYMLG-SALLVHPVTDPQTATIDVFLPGSDEVWYDSKTFAYWKG--GCTVKIPVTLDTIPVFQRGGSVVPVKTTVGTSTGWMADSPYELRVALSTQGSAVGELYLDDGHSFQYLHQNQFLYRKFLFCSSVLTNRCANEKGHYP-------SKCIVEQILVLG-----LKKKPSSVTTHLSDGRAQPAAFTYCAETSALRLEKLSLRIGEDWEVRVG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A7G5-1", "uniprot_id": "D4A7G5_RAT", "id": "D4A7G5-1", "name": "", "aln": "-----METPEKKEISVEDEAVDKTIFKDCGKIAFYRRQKQQLSKNTTYRASLGSVSTEQDSTR--------------FQISSEATKIPLVAEVYGIEKDIFRLKINEETPLKPR-------------------------------------YEVPDVVNSKLGTVRLVCS-GDTGSLTLTDRKGDLRCHISANPFKIDLLSKDEALISINSLGKLYFEHLRVPHKQRATKGNGQNTPADTFQENQEDLGLWEEKFG-KFVDVKVNGPSSVGLDFSLHGFEHLYGIPQHAESHQLKNTRDG-DAYRLYNLDVYGYQVHDKMGIYGSVPYLLAHKQGRTVGIFWLNASETLVEINTEPAAEYTLTQMGPAAAKQKVRCRTNVHWMSESGIIDVFLLTGPTPADIFKQYSYITG------------------TQAMPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDVMWLDIEHTEDKKYFTWDKKRFANPKRMQELLRSKGRKLVVISDPHIKVDPDYTVYAEAKERGFFVKNPEGGDLEGVCWPGLSSYLDFTNPK-VREWYSSLFAFPVYQGSTDILFLWNDMNEPSVFRGPELTMQKNAVHHGNWEHRELHNIYGFYHQMATAEGLIQRSQGKE-RPFVLSRSFFAGSQKYGAVWTGDNTAEWSYLKISIPMLLTLSVSGISFCGADVGGFIGNPEAELLVRWYQAAAYQPFFRGHATMNTKRREPWLFGAEYTQLIREAIRERYSLLPYLYSLFYHAHVSSQPVMRPLWVEFPDDLETFAVEDEYMLG-NALLVHPVTAPQTTMIDVFLPGSNEVWYNSKTFAYWKG--GCAVKVPVTLDTIPVFQRGGSVVPVKTTVGKSTGWMTDSPYGLRVALNTQGSAVGELYLDDGHSFQYLHQNQFLHRKFLFCSSVLTNRCADEKGHYP-------SKCIVEQILVLG-----LKKKPSSVTTHSSDGKVQPATFAYCAKTCTLSLKKLSLSVGDDWEVHVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TET4-1", "uniprot_id": "GANC_HUMAN", "id": "Q8TET4-1", "name": "Neutral alpha-glucosidase C", "aln": "-----MEAAVKEEISLEDEAVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTR--------------FQIINEASKVPLLAEIYGIEGNIFRLKINEETPLKPR-------------------------------------FEVPDVLTSKPSTVRLISCSGDTGSLILADGKGDLKCHITANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQRAAKENEEETSVDTSQENQEDLGLWEEKFG-KFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNTGDG-DAYRLYNLDVYGYQIYDKMGIYGSVPYLLAHKLGRTIGIFWLNASETLVEINTEPAVEYTLTQMGPVAAKQKVRSRTHVHWMSESGIIDVFLLTGPTPSDVFKQYSHLTG------------------TQAMPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDAMWLDIEHTEGKRYFTWDKNRFPNPKRMQELLRSKKRKLVVISDPHIKIDPDYSVYVKAKDQGFFVKNQEGEDFEGVCWPGLSSYLDFTNPK-VREWYSSLFAFPVYQGSTDILFLWNDMNEPSVFRGPEQTMQKNAIHHGNWEHRELHNIYGFYHQMATAEGLIKRSKGKE-RPFVLTRSFFAGSQKYGAVWTGDNTAEWSNLKISIPMLLTLSITGISFCGADIGGFIGNPETELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGEEHTRLIREAIRERYGLLPYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEYMLG-SALLVHPVTEPKATTVDVFLPGSNEVWYDYKTFAHWEG--GCTVKIPVALDTIPVFQRGGSVIPIKTTVGKSTGWMTESSYGLRVALSTKGSSVGELYLDDGHSFQYLHQKQFLHRKFSFCSSVLINSFADQRGHYP-------SKCVVEKILVLG-----FRKEPSSVTTHSSDGKDQPVAFTYCAKTSILSLEKLSLNIATDWEVRII", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P9M8-1", "uniprot_id": "A0A8M9P9M8_DANRE", "id": "A0A8M9P9M8-1", "name": "", "aln": "-----MEVNVSTES-IESVLKSEDKFRKNHEILFYRRQRD--KAVSQYFTSYETFVLTDGGAS--------------LELCERDSQDRLSLQIRATQNGTIRVSIDELQLVKPR-------------------------------------YQVSDVLVGELRYEPLRVEWKKEDCVCLTWGLGQYQLLAFFSPFKLEISCAGEEIVTLNPGNKLCFETLQDPASR---------SSSNSSEGDENCCGLWKETFR-QFEDIKANGPSSVGLDLSLHGFNHTYGVPEHADTLLLKDTSVS-EAYRLYNLDVFGYEINSRLGLYGSVPLLLAHKPERTAGVFWLNSSETLVDVKYN--TEQNEDEDEPPGKKSRISPRTDVRWISESGTIDCFILLGPTPAQVFSQYAQLTGKCRCRLYNGCARNRPLLSYQALPPLFSLGNHQCRWNYEDEADVKAVDAGFDLHGIPYDVIWLDIEHTDGKRYFTWDSKRFPNPAELQHHLMKKKRKLVVISDPHIKMDPDWSIYCEAKKGGHFVKNREGFDFEGTCWPGESCYLDFSSSK-TRLWYARQFSLSKYEGSTESLFVWNDMNEPSVFNGPEQTMPKDALHHGGWEHRELHNLYGFYQHMATFEGLLTRSGGTE-RPFILTRSFFAGSQRLGAIWTGDNVATWEYLKISIPMLLSLSLTGIQFCGADVGGFVQDPDPELLVRWYQAGALQPFFRAHSAKMTKRREPWLFGEEVTSAIRSAVQDRYCLLPYWYTLFHQAHTAALPPIRPLWVEFPKDTSTFAVENQYMIG-GALLVCPVTDPGVTEVKVLLPGSNELWYDTNTSEVHKG--ARSLDVPVTLTTVLVFQRGGTVVPRRTACGSCTADLQHYTITLTVALDIKGKADGFLYLDDGHSFNYRDQMQFCLRRFSMQAGRLVNSCANDKGLFV-------SDDKVETVVILG-----LKSVKRKPKLKSG-AKRTSVMFEFDKKRGVLTLSGLELEICKDWEIII-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38138-1", "uniprot_id": "GLU2A_YEAST", "id": "P38138-1", "name": "Glucosidase 2 subunit alpha", "aln": "MVLLKWLVCQLVFFTAFSHAFTDYLLKKCAQSGFCHRNRVYAENIAKSHHCYYKVDAESIAHDPLENVLHATIIKTIPRLEGDDIAVQFPFSLSFLQDHSVRFTINEKERMPTNSSGLLISSQRFNETWKYAFDKKFQEEANRTSIPQFHFLKQKQTVNSFWSKISSFLSLSNSTADTFHLRNGDVSVEIFAEPFQLKVYWQNALKLIVNEQNFLNIEHHRTKQEN-----------FAHVLPEETTFNMFKDNFLYSKHDSMPLGPESVALDFSFMGSTNVYGIPEHATSLRLMDTSGGKEPYRLFNVDVFEYNIGTSQPMYGSIPFMFSSS---STSIFWVNAADTWVDIKYDTSKNKTMT-----------------HWISENGVIDVVMSLGPDIPTIIDKFTDLTG------------------RPFLPPISSIGYHQCRWNYNDEMDVLTVDSQMDAHMIPYDFIWLDLEYTNDKKYFTWKQHSFPNPKRLLSKLKKLGRNLVVLIDPHLKKD--YEISDRVINENVAVKDHNGNDYVGHCWPGNSIWIDTISKYGQKIWKSFFERFMDLPADLTNLFIWNDMNEPSIFDGPETTAPKDLIHDNYIEERSVHNIYGLSVHEATYDAIKSIYSPSDKRPFLLTRAFFAGSQRTAATWTGDNVANWDYLKISIPMVLSNNIAGMPFIGADIAGFAEDPTPELIARWYQAGLWYPFFRAHAHIDTKRREPYLFNEPLKSIVRDIIQLRYFLLPTLYTMFHKSSVTGFPIMNPMFIEHPEFAELYHIDNQFYWSNSGLLVKPVTEPGQSETEMVFPPGIFYEFASLHSFINNGTDLIEKNISAPLDKIPLFIEGGHIITMKDKYRRSSMLMKNDPYVIVIAPDTEGRAVGDLYVDDGETFGYQRG-EYVETQFIFENNTLKNVRSHIPENLTGIHHNTLRNTNIEKIIIAKNNLQHNITLKDSIKVKKNGEESSLPTRSSYENDNKITILNLSLDITEDWEVIF-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . ::. : * :*:: : .. . . .: : .: : .*..*:* : . . . : *: .**::.: : :* . * :* : .. :: .::::.* . * **.*:.**:*: * : **:*:** : * :* . :.***:*:**: *:: :***:* ::: . : .:**:*:::* *::: : : . :*:**.* ** .: ** . ::.::: :** :**: *:* *******:** ** :**: :* * **** :***:*:*:.*:****..: *.** .: * . *:***: ***:* * : : .. . . **: :* * * **** * ::* . : * : : .. **:********:* *** * *. :* . *.*.:**:**: : ** :.: .: ***:*:*:******: .* ***** * *. *******:*: .::*: * ***:.** :* .**:.*****. ****.*: ******:**. . :*. :: ** *** *::*::: .:. * :.*:::*.*. . : ::::: . ..*** *** * : .:.:* . : :* .:...* .: :* .** ::. : .: : . . : :* . :* : * **:***.:* * :: :* : . * * :. . :* ::: . . . : . . : : : *.* : ***: . ", "identical_positions": 235, "similar_positions": 269, "identity": "23.34%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-756", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z1S8-1", "uniprot_id": "GAB2_MOUSE", "id": "Q9Z1S8-1", "name": "GRB2-associated-binding protein 2", "aln": "MSGGGGDDVVCTGWLRKSPPEKKLRRYAWKKRWFILRSGRMSGDPDVLEYYKNEHSKKPLRIINLNLCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLVAETEADMNKWVQSICQICGFNQAEESTDSLRNLSSASHGPRSSPAEFSSS-QHLLRERKSSAPSHSSQPTLFTFEPPVSSHMQPTLSTSAPQEYLYLHQCISRRTENARSASFSQGTRQ----KSDTAVQKLAQSNGHCINGVGGQVHGFYSLPKPSRHN-----TEFKDSTYDLPRSLASHGHTKSSLTGSETDNEDVYTFKMPSNTLCRELG--DLLVDNMDVPTTPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRPPKPSQAETSQWGSIQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPARGSGESASWSAE---------PPGKTAVGRSNSASSDDNYVPMNPGSSTLLAMERPGDNSQSVYIPMSPGPHHFDPLGYPSTALPIHRG--------PSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELPFKSPVTKSWSRINHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPGSPSPHRKPSTSSVTSDEKVDYVQVDKEKTQALQNTMQEWTDVRQSSEPSKGAKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQC2-1", "uniprot_id": "GAB2_HUMAN", "id": "Q9UQC2-1", "name": "GRB2-associated-binding protein 2", "aln": "MSGGG--DVVCTGWLRKSPPEKKLRRYAWKKRWFILRSGRMSGDPDVLEYYKNDHSKKPLRIINLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLVAETEEDMNKWVQSICQICGFNQAEESTDSLRNVSSAGHGPRSSPAELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSNHMQPTLSTSAPQEYLYLHQCISRRAENARSASFSQGTRASFLMRSDTAVQKLAQGNGHCVNGISGQVHGFYSLPKPSRHN-----TEFRDSTYDLPRSLASHGHTKGSLTGSETDNEDVYTFKTPSNTLCREFG--DLLVDNMDVPATPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRPPKPSQAETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPQRG-GESAGRSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPGSSTLLAMERAGDNSQSVYIPMSPGAHHFDSLGYPSTTLPVHRG--------PSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELPFKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVPSGTNSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSDEKVDYVQVDKEKTQALQNTMQEWTDVRQSSEPSKGAKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7A7-1", "uniprot_id": "A0ACD6B7A7_DANRE", "id": "A0ACD6B7A7-1", "name": "", "aln": "MSGGE---IICQGWLRKSPPEKKLRRYAWKKRWFILRSGRMSGDPDVLEYYKSDHAKKPIRIIDLHCCEQVDAGLTFKRKEFQDSFVFDIKTAERTFYLVAETEEEMNRWVRSICQLCGFNQSEENHHDERSSSIS----RSLTNELSSSLAPLIGERKTSVPAHSSQPMLFTFDIPVR-HSHGPLSNSAPQDYLFLHQCMSRKSESARSASFSQASRSSLLVGSDSAVQRLTHGFSHCLNGMGAQLHGFYSLPKPGKHQQPPSRTDSQEACYVLPRNYSSEG-------ASELDSEDVYTFKTPNNTLAAPQTNEQRALDNYDLP-----IYQIPRTF--DKNHNALMPSN-ADSTSAPPPRPPKPSQGSESRWGGTLPTG-AQNGEVSTASVIPRRNTLPAVENIKLHRGSSFETSSHQRPVYFNNSGQSVESVNDGFSSYLRTKAPLTRSDSAGSDDNYVPMNPGSSSSPLSAALADSPKNNYIPMSPGPHHFDFPGF-SATLPARKGSTASLCLRPGRLSDVTPPPINRNLKP-RTAKPTPLDLRNNGIIDELPFKSPITMSWTRP-MPMNSISSQHCRPISTQSITSTDSADSEENYVAMQNPVSTSPAMSGTSSPAPRN-CGNVDYLALDFQPGSPGPHRKPSTSSVTSDEKVDYVQVDKEKTQALQNTMQEWTDVRQSSEPAKGIKS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** ::* ****************************************.:*:***:***:*: **********::**:**********:*********** :**:**:****:*****:**. .. *. * : ** . *:*** *: ***:*.*:***** ****: ** * : .**.****:**:****:**::*.********.:* **:***:*::. .**:**:..*:*********.:*: *: ::: * ***. :*.* .** *.******* *.***. : :** *:* ******* ******: :. .**: ***********.. .:**. .:.. *.*:.*********::* :***.** ** .: :.:. *.* * : **:*:.*:***********: .*..:. *******.**** *: *::** ::* *.* *:: ***:****** *.*********** :*********:* **:* .:** ***:**************.*******.******:**. ***.****:: *.**********.**.*********************************************:** * ", "identical_positions": 418, "similar_positions": 135, "identity": "60.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-757", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJT2-1", "uniprot_id": "GFRA4_MOUSE", "id": "Q9JJT2-1", "name": "GDNF family receptor alpha-4", "aln": "-------MAHCMESALLLLLLLGSASFTDG----------------------------------------------------------------------------------------------------------------NRCVDAAEACTADERCQQLRSEYVARCLGRAAPGGRPGPGGCVRSRCRRALRRFFARGPPALTHALLFCGCEGSACAERRRQTFAPACAFSGPGLVPPSCLEPLERCERSRLCR-------------------PRLLAFQAS-------CAPAPGSRDRCPEEGG---PRCLRVYAGL-IGTVVTPNYLDNVSARVAPWCGCAASGNRREECEAFRKLFTRNPCLDGAIQAFDS--------------------------------------LQP------SVLQDQTAGCCFPRVSWLYALTALALQALL---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZZ7-1", "uniprot_id": "GFRA4_HUMAN", "id": "Q9GZZ7-1", "name": "GDNF family receptor alpha-4", "aln": "-------MVRCLGPALLLLLLLGSASSVGG----------------------------------------------------------------------------------------------------------------NRCVDAAEACTADARCQRLRSEYVAQCLGRAAQGG------CPRARCRRALRRFFARGPPALTHALLFCPCAGPACAERRRQTFVPSCAFSGPGPAPPSCLEPLNFCERSRVCRCARAAAGPWRGWGRGLSPAHRPPAAQASPPGLSGLVHPSAQRPRRLPAGPGRPLPARLRGPRGVPAGTAVTPNYVDNVSARVAPWCDCGASGNRREDCEAFRGLFTRNRCLDGAIQAFASGWPPVLL-----------------------------DQLNPQGDPEHSLLQVSSTGRALERRSLLSILPVLALPALL---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F0C7-1", "uniprot_id": "E7F0C7_DANRE", "id": "E7F0C7-1", "name": "", "aln": "MDLMGIYLLHLSFAALQVLLYASRDCLIAGDTCSSDETCSPRLRTLRQCVAGNGSMKLGPGARSQCANAVSALLSTPLHRCQCRRGMKREKNCLSIYWSLHQSGMHGLNLVENYPYETVEKGYEFVRLASITADSEIGMSTVNRCLDAAKACNIDDVCQRLRTEYVSTCIKPSTKSG-----LCNRSRCNKALRRFFDRVPAEYTHELLFCPCSDMACSERRRQTIVPSCSYEGED--KPSCLSQMRICKADYVCR-------------------SRLAQFQYD-------CQPDEQSATGCTQGNY---AACLIAYTGM-IGSPITPNYVDNFTSEVSPWCSCSASGNLKDQCSDFLDYFTNNVCLQNALLTFGNGLDFTPTPTQLLRLNPATDRGPWRTTSVFVTLETEQSTLSPAKPTQDSVKVRLWSDSTPSFDTQQNSAQALAVTSLLVWICLFLSLLLSCDQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .** :** . . * ***:***:**. * **:**:***: *: :: .* * *:**.:****** * *. ** **** * . **:******:.*:*::.* . ****. :. *: . :** * * . * . . * *: *: :****:**.::.*:***.*.**** :::*. * **.* **:.*: :* . *.* *: :. : .**: :** ", "identical_positions": 97, "similar_positions": 67, "identity": "20.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-758", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VCE7-1", "uniprot_id": "Q9VCE7_DROME", "id": "Q9VCE7-1", "name": "", "aln": "MKMVDKSSKLVDKFAVISGTGGSGPGGGPLNLQSGGGGGGSGGGGGVSGSGGISGTAGLSAGAGMTTGQKPVPMKLFAAWEVDRTPPNCIPRLCSLTITRLSILTPLPGDTTSLSLAVKMQSSKRTLRSHEIPINGLALTSSASLQGNSPMSVAGGVGGGGVGTPGSVGTGGGLGVAVPLTETELDLHFSLQYPHFIKRDGNRLVILLQRRKKYKSRTILGYKTLAEGIIRMDAVLQKSMDMIIELTASGKNGRPGTVVACLRAERVSSIPVDHDNKNNNSVLLADRVAEYSDEDEEAEFSSGEFNDEANELGLIRGYDPKDPRDYNHPAKHDMRKYRNKLQRSGIEDCALVGHHPGSIQHHHPGVVVDSDSEFEMKDKSSSRAKFSRTISLQ-QRNFKQKIVALLKRFKVSEELEGESGHRGTAALRGERDLDALFQELESLSCCEGDDSGPDMDSISVGSTPKPSLRPFFTNSRIMLHDNITGNGGDLSQLVGGGLGPGTGTAGNSERRSSDKSDQLTNSSYNLENNKNQKCIHLTNNNNSATTPDRGGNDSSGNEGNAGYTDGQNSDPQNSPPRDKDYLRLQQMQQQQLTPVSSVAASMGSGSVITPAQTEKRSRLFRTSSNTPANAGSGGNSVSAISASGGGKRKHTLSLSAEPRSVLEACLSPTNVEPRKLLLDQLSRVFAGEDSAIPEVVTIISPPEALGGSALLAKLVTLFANSFKPAFVPQNTAEVKAVLQALMAKIQKYCNSNAKPPHTVKVLLIGGDWLQGATLRHYVELMGVRPPDWLNHLRFYLVPVGGSCGSVARHLSQMDQAYAVMFGSDNWTQLCERAAATAAAVSAVTTVNATALTTNLADAAGVAKSDIAELVQRIQRYLLAAGPCTQIPIAEAMVNYK---------------DEDSCQIFVPFVSDVRIGYLDAQASLDLEENAAGSNAVGSGLGSGSASSSAIPIGSQSSPNVHGVVSGSPPQQQSLGRISPPLQTPPSSASSHRERNTSESLSTPSSVQQQSFSGALAAAEAVELQVDYWPLVRPGEGHAKESKGGLSKGSDAGGKNSIKSTFRNLQVWRLPQHAQQLGDMFNGLTVSFATKEKKQKQIMRLGKKKDKERDLEKEQCVEGVARLICSPKQSHPVPLRVYIDGTEWTGVKFFQVSSQWQTHVKNFPIALIGCTPMSCAELS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M9QAQ5-1", "uniprot_id": "A0A8M9QAQ5_DANRE", "id": "A0A8M9QAQ5-1", "name": "", "aln": "---------------------------------------MMAAALDRGGQRVIPAADPVSGALLCGSGSTPVPMNLFATWEIDRSSPSCVPRLCSLTLKRLIVLKELDKDLNSVLIAVKIQGSKRVLRSNEYALP-----------------------------------------PSGVMETELELTFSLQYPHFLKRDANRLQIMLQRRKRYKNRTILGYKTLAVGVINMAEVLQHPTEGGQILHLHGNMKDAPTRLAEISVFSLSSQPIDHEYSSGTGGAAIKASDRSPDMDNYSEDDEDSYSSEQ----------------------------------------------EGSDDAGHTQDLYDEDD--DLRKPKKPRRKMTRSFSMTRQPNFKQKFVALLKRFKVSDEVLDSDPVEQTQEVE-EEDLDLLYDSLEVFNQSDSGPELEDTDSLLS--TPKPKLRPFFEG------------------------------------MSHSSSQTEISSVHSQHTALNTGCDFLSVDRSKKTSSRQQEDSSMETSGGEADAEHHGIAMADVLESSSDRLNISGGKLCKSESQNHSKAEVRAPRRIRSTSMKDRQ-----------------------NSRAQSERTISMDSQYTPHSRFTAQVP------RKSVYDQLNQILIS-DERLPENIILINTVDWQG-----QYVAEILQKHTQPIVSTCSAADVQAAFNTIVTRIQRFCNCNAQTPPTVKVAVTGDQSYLSTVLRFFVEQLANKTPDWLSYIRFLIIPIG--SHPLAKYMASFDSKFSSMFMEPSWRELFCRPEP--------------------------PNTDSVDVAGRIIQYLAGANVCHQFPISEAMLTYRQKRKRSLYFDLYISPDEDSCQKFVPFIGVVKVGIVEHSLSTSVDSDDAMGGGVG----------VASPFMMQSATPYGREICVTPPPSPSACAVFTGVGSPCTGG------------------------------ELMGLQVDYWVCVSGDRKREGEKR-------EVGLKNTLKSNFRSLQVSRLPSGGDTAHTHT--LAMTVVTKEKNKKVIFLSKKPKEKEVDS-KSQVIDGISRLICTAKHQH-TMLRVCIDGVEWNDVKFFQLAAQWPTHVKHFPVGVFGYSKPV-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 309, "similar_positions": 336, "identity": "25.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-765", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9P246-1", "uniprot_id": "STIM2_HUMAN", "id": "Q9P246-1", "name": "Stromal interaction molecule 2", "aln": "MLVLGLLVAGAADGCELVPRHLRGRRATGSAATAASSPAAAAGDSPALMTDPCMSLSPPCFTEEDRFSLEALQTIHKQMDDDKDGGIEVEESDEFIREDMKYKDATNKHSHLHREDKHITIEDLWKRWKTSEVHNWTLEDTLQWLIEFVELPQYEKNFRDNNVKGTTLPRIAVHEPSFMISQLKISDRSHRQKLQLKALDVVLFGPLTRPPHNWMKDFILTVSIVIGVGGCWFAYTQNKTSKEHVAKMMKDLESLQTAEQSLMDLQERLEKAQEENRNVAVEKQNLERKMMDEINYAKEEACRLRELREGAECELSRRQYAEQELEQVRMALKKAEKEFELRSSWSVPDALQKWLQLTHEVEVQYYNIKRQNAEMQLAIAKDEAEKIKKKRSTVFGTLHVAHSSSLDEVDHKILEAKKALSELTTCLRERLFRWQQIEKICGFQIAHNSGLPSLTSSLYSDHSWVVMPRVSIPPYPIAGGVDDLDEDTPPIVSQFPGTMAKP---PGSLARS-----------------------------------------------------------SSLCR--------------------------------SRRS---------IVPSSPQPQRAQLAPHAPHPSHPR----HPHHPQHTPHSLPSPD----PDILSVSSCPALYRNEEEE-EAIYFSAEKQWEVPDTASECDSLN-----------SSIGRKQSPPLS---------LEIYQTLSPRKISRD-------EVSLEDSSRGDSPVTVDVSWGSPDCVG--------------------------------LTETKSMIFS-------PASKVYNG----ILEKSCSMNQLSS--------------GIPVPKPRHTS------CSSAGNDSKP------------------------VQEAPSVARISSIPHDLCHNG---------------------------EKSKKPSKIKSLFKKKSK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P83093-1", "uniprot_id": "STIM2_MOUSE", "id": "P83093-1", "name": "Stromal interaction molecule 2", "aln": "MLLFGLLVAGVADGCDLVPRHLRGRRASGSAGAAASPSAAAAGERQALLTDPCMSLSPPCFTEEDRFSLEALQTIHKQMDDDKDGGIEVDESDEFIREDMKYKDATNKHSHLHREDKHITVEDLWKQWKTSEVHNWTLEDTLQWLIEFVELPQYEKNFRDNNVKGTTLPRIAVHETSFMISQLKISDRSHRQKLQLKALDVVLFGPLTRPPHNWMKDFILTISIVIGVGGCWFAYTQNKTSKEHVAKMMKDLESLQTAEQSLMDLQERLEKAQEENRTVAVEKQNLERKMMDEINYAKEEACRLRELREGAECELSRRQYAEQELEQVRMALKKAEKEFELRSSWSVPDALQKWLQLTHEVEVQYYNIKRQNAEMQLAIAKDEAEKIKKKRSTVFGTLHVAHSSSLDEVDHKILEAKKALSELTTCLRERLFRWQQIEKICGFQIAHNSGLPSLTSSLYSDHSWVVMPRVSIPPYPIAGGVDDLDEDTPPIVPQFPGTVAKP---AGSLARS-----------------------------------------------------------SSLCR--------------------------------SRRS---------IVPSSPQSQRAQLPAHAPLAAHPR----HPHHPQHPQHSLPSPD----PDILSVSSCPALYRNEEEE-EAIYFTAEKQWEVPDTASECDSLN-----------SSSGRKPSPPSS---------LEMYQTLSSRKISRD-------ELSLEDSSRGESPVTADVSRGSPECVG--------------------------------LTETKSMIFS-------PASRVYNG----ILEKSCSMHQLSS--------------GIPVPHPRHTS------CSSAGNDSKP------------------------VQEASNVSRVSSIPHDLCHNG---------------------------EKSKKPSKIKSLFKKKSK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B5U6-1", "uniprot_id": "A0ACD6B5U6_DANRE", "id": "A0ACD6B5U6-1", "name": "", "aln": "----------MQKFCLTVLLVLRGLIICVCSSDQAQQQPGLNRDTTVTPIDPCLQMSPPCITEADRFSLEALQHIHREMDDDQDGGIEVEESVEFIIEDMQQQQQANKHSKLHHEDQHITLEELWRSWKSSEVHNWTQEDVLQWLREFVELPQYEKSFKELRVSGNTLPRIASNEPSFMSSYLKIQDQQHKQKLKLKALDVVLFGPPIRPPHNWMKDVLLIVSIVMGIGGCWFAHVQSKSSKVHISKMMKDLESLQRAEQSLRDLQEQLEKAQEEKRTVTVEKKNLEEKMRDEIQGAQEEANRLHRLRDGAVTELSRLWYAEEELEQVRGALKRAEKDMQT--LWSVPESLQLWLQLTHEVEVQYYNVKKQSAEQQLITAKDEAEKIKKKRSSVLGTLHVAHSSSLDQVDQRILEAKNALAEVTACLRERLHRWQQIESLCGFPLMKNAGLPNLTATLYPDPNWMLMPRAALQSYQVPVSVEDMEEEMPQIIPQIPVTVAPLKCSPRSLVRSRRSGHMVPSPVIVSPDPDLLIPIRSPQSRYGDDEEGHIKYTPIVKQESMETSSDTESIGSSISRKYSTLDVPPRRKYIFSDKMPRKISLDEQEDTSSRKTSQEEMDESLMVTTSRKASREELDINTPSRKTSREELDEPPKQLFRGETEICFDSRKLPRDLSLDSTVRYYSTEKMSPVAISMDSQRQRSIRERKDHMDSISRVIPKAEFDIDATTGSRYADALLNTSIKHKENLDFASNIQRGRMFRENSFDANFDSSVESSKKLKTLARADLSKDIPSRMMTQDEFDASADLERLKMRDIAMETASRNILREEFDRSKSLKESRDIRMEIPSKKLFRDEQEVAMETQRIQQKLDSSLETPISKIQRELMGLSVEAPRRKISQEEFVVSNPGQFGPPDLTASSLMLCKPQLDSISTLVYDGILEKSYESPLMSSPGDLSHAASVSSSIQSLVGNEGQSAHSSSSESGGKEKGKKTSKLKSLFKKKKEKDKDS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * *** .:. *. .. : . ***:.:****:** ********* **::****:******:** *** ***: :: :****:**:**:***:*:**: **:******* **.**** **********.*:: .*.*.****** :*.*** * ***.*:.*:***:*********** *********.:* :***:*:******:.*.*:** *::********** ***** ****:*******:*.*:***:***.** ***: *:*** **:.**:** **** ***:****** ***:***::: ****::** **************:*:*.** ** *************:*:************:**::*****:**:*:*:******.******.:*** : :*:***.**::**.* .*::***.:: .* :. .*:*::*: * *:.*:* *:* . **.** **:.* **:: :*.:* :..* :* ::* .* .* : . .: . * * **:.* * .*: . ** : :::* .: : .. **:. :: * : : . *:: ..:. :: *: : *:*.*.: .: . .*:* . *. : : .:**: * *:.:::.. :*.. ::*.* *:.* **:. *..*: . * : * . : : * * **.* . **.**.**:*******.: ", "identical_positions": 380, "similar_positions": 212, "identity": "37.85%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-768", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A773-1", "uniprot_id": "A0A8I6A773_RAT", "id": "A0A8I6A773-1", "name": "Ninein-like protein", "aln": "MDNEEENHYVSRLRDVYSSCDTTGTGFLDQEELTQLCTKLGLEEQLPALLHILLGDGRLARVNFEEFKEGFVAVLSSATGVEPSDEEGSSSESATSCAVPPKYMSGSKWYGRRSLPE------LGDSATTTKCGSEQQAKGSVKPPLRRSASLESVESLKSDEDAESPKEPQNELFEAQGQLRSWGCEVFGTPRKSCSPSFNTPENQVQGIWHELGVGSSGHLNEQELAVVCRSIGLHGLEKQELEELFSKLDRDGDGRVSLAEFQLGLFGHEPPSLPASSSLIKPNGPWSHYQ--EESGCHTTTTSSLVSVCSGLRLFSSVDDGSGFAFPEQVISAWAQEGIQNGREILQS--LDFNVDEKVNLLELTWALDNELLTVD-----GVIQQAALACYRQELNFHQGQVEQLVQERDKARQDLEKAEKRNLDFVREMDDCHSALEQLTEKKIKHLEQEYRGRLSLLRSEVEMERELFWEQARRQRAVLEQDVGRLQAEETSLREKLTLALKENSRLQKEIIEVVEKLSDSEKLVLRLQSDLQFVLKDKLE---PQSMELLAQEEQFTAILNDYELKCRDLQDRNDELQAELEGLRVRLPRSRQSPSGT-----------------------------PGTHRRWTPGRGPADNLFVGESIPVSLETEIKMQQMKENY----QELRMQLETKVNYYEKEIEVMKRNFEKDKKEMEQAFQLEVSVLEGQKADLETLYAKSQEVILGLKEQLQDAARSPEPAPAGLAPCCAQALCTLAQRLGVEMHLRHQDQLLQIRLSDTVTDSVLPRVCSPKGSRKRTGHPNTKQTTERRVSGREAEEELNQKLSWLEAQHAACCESLSLQHQCEKDQLLQTHLQRVKDLAAQLDLEKGWREEREQEVLAHCRRQQLKLQAVMSEEQARICRSFTLEKEKLEQTYREQVEGLVQEADVLRALLKNGTTVVSDQQERIPGSMYPGPDSRQQPPTWQTVSPDGRTGAPAEWPGPGRADGRDLPGQLCSLDAVPSPTPTLLSRRSSESLDVRDNHQGPLSAEEGAVPKEPEPSARTLTGQDQ----KLPLP--------IQPQMLEPWLGPAAVDR--------------KPDSVRVQGQASEGPTGDDKGVQETPLQLRGETARMRPSLPYSELPNPQ----------EAKVMSVMSESEMNDVKTKLLQLEDVVRALEK-ADSRESYRAELQRLSEENSVLKSDLGKIQLELGTSESRNEVQRQEIEVLKRDKEQACFDLEELSTQTQKYKDEMSQLNCRILQLEGD----SSGLHTQKEENHAAIQVLMKKLEEAECREKQQGDQIKHLKIELERVNEECQRLRLSQAELTGSLEESQGQLHSVQLRLEAAQSQHDRIVQGLQEQMSQ-------------LVPGARVAELQHLLSLREEEAER-LNAQQEEYKQQLKAREDQVEEAEARLHNVEWLLQEKVEELRKQFEKNTRSDLLLKELYVENAHLMKAVQLTEEKQRGAEKKNCVLEEKVRALNKLISKMAPASLSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZQ12-3", "uniprot_id": "NINL_MOUSE", "id": "Q6ZQ12-3", "name": "Ninein-like protein", "aln": "MDNEEENHYVSRLRDVYSSCDTTGTGFLDQEELTQLCTKLGLEEQLPALLHILLGDDRLARVNFEEFKEGFVAVLSSGSGVEPSDEEGSSSESATSCAVPPKYMSGSKWYGRRSLPE------LGDSATATKYGSEQQAKGSVKPPLRRSASLESVESLKSDEDAESAKEPQNELFEAQGQLRSWGCEVFGTLRKSCSPSFSTPENLVQGIWHELGIGSSGHLNEQELAVVCRSIGLHSLEKQELEELFSKLDQDGDGRVSLAEFQLGLFGHEPPSLPASSSLIKPNRLWSHYQ--EESGCHTTTTSSLVSVCSGLRLFSSVDDGSGFAFPEQVISAWAQEGIQNGREILQS--LDFSVDEKVNLLELTWALDNELLTVD-----GVIQQAALACYRQELSYHQGQVDQLVQERDKARQDLEKAEKRNLDFVREMDDCHSALEQLTEKKIKHLEQEYRGRLSLLRSEVEMERELFWEQARRQRAVLEQDVGRLQAEETSLREKLTLALKENSRLQKEIIEVVEKLSDSEKLVLRLQSDLQFVLKDKLE---PQSMELLAQEEQFTAILNDYELKCRDLQDRNDELQAELEGLRLRLPRSRQSPAGT-----------------------------PGTHRRRIPGRGPADNLFVGESTPVSLETEIMVEQMKEHY----QELRMQLETKVNYYEKEIEVMKRNFEKDKKEMEQAFQLEVSVLEGQKADLEALYAKSQEVILGLKEQLQDAAQSPEPAPAGLAHCCAQALCTLAQRLEVEMHLRHQDQLLQIR--------------------------------------QEAEEELNQKLSWLEAQHAACCESLSLQHQCEKDQLLQTHLQRVKDLAAQLDLEKGRREEREQEVLAHCRRQQLKLQAVMSEEQARICRSFTLEKEKLEQTYREQVEGLVQEADVLRALLKNGTTVVSDQQERTPSSMSLGPDSRQQPTARQAVSPDGRTGAPAEWPGPEKAEGRDFPGQLCSIDAMPSPTPTLLSRRSSENLGVRDNHQRPLNAEEGAIPKEPEPSARTLTGQGQ----KLPLP--------VHPQMLEPSLGTTALDR--------------KAASVGVQGQASEGPVGDGEGVQEAWLQFRGEATRMRPSLPCSELPNPQ----------EATVMPAMSESEMKDVKIKLLQLEDVVRALEK-ADSRESYRAELQRLSEENLVLKSDLGKIQLELETSESKNEVQRQEIEVLKRDKEQACCDLEELSTQTQKYKDEMSQLNCRVLQLEGE----PSGLHTQKEENHGAIQVLMKKLEEAGCREEQQGDQIQNLKIELERVNEECQYLRLSQAELTESLEESRSQLYSVQLRLEAAQSQHGRIVQRLQEQMSQ-------------LVPGARVAELQHLLNVKEEEARR-LSAQQEEYRQQLKAREDQVEDAEARLRNVEWLLQEKVEELRKQFEKNTRSDLLLKELYVENAHLMKAVQLTEEKQRGAEKKNCVLEEKVRALNKLISKMAPASLSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2I6-1", "uniprot_id": "NINL_HUMAN", "id": "Q9Y2I6-1", "name": "Ninein-like protein", "aln": "MD-EEENHYVSQLREVYSSCDTTGTGFLDRQELTQLCLKLHLEQQLPVLLQTLLGNDHFARVNFEEFKEGFVAVLSSNAGVRPSDEDSSSLESAASSAIPPKYVNGSKWYGRRSRPE------LCDAATEARRVPEQQTQASLKSHLWRSASLESVESPKSDEEAESTKEAQNELFEAQGQLQTWDSEDFGSPQKSCSPSFDTPESQIRGVWEELGVGSSGHLSEQELAVVCQSVGLQGLEKEELEDLFNKLDQDGDGKVSLEEFQLGLFSHEPALLLESSTRVKPSKAWSHYQVPEESGCHTTTTSSLVSLCSSLRLFSSIDDGSGFAFPDQVLAMWTQEGIQNGREILQS--LDFSVDEKVNLLELTWALDNELMTVD-----SAVQQAALACYHQELSYQQGQVEQLARERDKARQDLERAEKRNLEFVKEMDDCHSTLEQLTEKKIKHLEQGYRERLSLLRSEVEAERELFWEQAHRQRAALEWDVGRLQAEEAGLREKLTLALKENSRLQKEIVEVVEKLSDSERLALKLQKDLEFVLKDKLE---PQSAELLAQEERFAAVLKEYELKCRDLQDRNDELQAELEGLWARLPKNRHSPSWS-----------------------------PDGRRRQLPGLGPAGISFLGNSAPVSIETELMMEQVKEHY----QDLRTQLETKVNYYEREIAALKRNFEKERKDMEQARRREVSVLEGQKADLEELHEKSQEVIWGLQEQLQDTARGPEPEQMGLAPCCTQALCGLA--------LRHHSHLQQIR--------------------------------------REAEAELSGELSGLGALPARRDLTLELEEPP------QGPLPRGSQRSEQLELER-----------------ALKLQPCASEKRAQMCVSLALEEEELELARGKRVDGPSLEAEMQ-ALPKDG-LVAGSGQEGTRGLLPLRPGCGERPLAWLAPG-DGRESEEAAGAGPRRRQAQDTEATQS-----PAPAPAPASHGPSE----RWSRMQPCGVDGDIVPKEPEPFGASAAGLEQPGARELPLLGTERDASQTQPRMWEPPLRPAASCRGQAERLQAIQEERARSWSRGTQEQASEQQARAEGALEPGCHKHSVEVARRGSLPSHLQLADPQGSWQEQLAAPEEGETKIALEREKDDMETKLLHLEDVVRALEKHVDLRENDRLEFHRLSEENTLLKNDLGRVRQELEAAESTHDAQRKEIEVLKKDKEKACSEMEVLNRQNQNYKDQLSQLNVRVLQLGQE----ASTHQAQNEEHRVTIQMLTQSLEEVVRSGQQQSDQIQKLRVELECLNQEHQSLQLPWSELTQTLEESQDQVQGAHLRLRQAQAQHLQEVR---------------------LVPQDRVAELHRLLSLQGEQARRRLDAQREEHEKQLKATEERVEEAEMILKNMEMLLQEKVDKLKEQFEKNTKSDLLLKELYVENAHLVRALQATEEKQRGAEKQSRLLEEKVRALNKLVSRIAPAALSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G9G127-1", "uniprot_id": "NINL_DANRE", "id": "G9G127-1", "name": "Ninein-like protein", "aln": "MDEDEQNRYVAQLKDEFDSCDTTGTGYLDKEELTALCHKLSLDAHLPLLLDTLLGPQHYARVNFEEFKEGFVAVLSRSLDFSTSEEESSYLEPAVPEEVKPKYVKGTKRYGRRSRPDKTDLELTADSDSLPFGTDKVEANGVRRAKLRRSTSLESVESLKSDEDTGSNKESTHHYFVAQGQLKLWNQDGTGNCQRSSDNQQEVTDGQVRAVWEELGVGAAGSLNREELSLVCDHIGLKHLEAEELDALFRKLDKDQDGKVSLIEFQSGLFKPHDHASPLSTSTPARPKPLRTISKALEERVVRSTSPSLLSATVGQRLLTRLDDGSGCTSPEKVMALWTEEGIHNSRDILQTQTLDFSLEERLCLAELTLALDNELLVSG-----NGIHQAALVSYKNEINYLQVLADQACQERDKAKADLEQADRRNLQLVREVDDRHATMESLNESKIKDLEQEFRDKLTALRSESEYESEVLLEQVEKERERLRDELQLLRSQDISLQEDMCTTVNENRRLEEEVSALKEKLTEAESAISKLQNDLDRLLQDKYDGLDANGTGLLNQEEQFTEIFKEYEQQCRELQDRNDELCSELELLKSQGSGKRTRLSRSSLPANDWSNRRALTTESDSDDPEMKKGTSPQVRKKLQVTDKNVLGSLESLAPPVSIETELAMEKMKERYEQEVQDLKIQLETKVNFYERSMDLMRQNMEVERKDISQSFKMEISELEDLKARAEERAEQMRQTTERLEAELRGKTSGG---------------------------------------------------------------------------------------------------------------------AWGQEQERRIQRER------------------AELEQNYAREISNLVLRLTSEKDQLEAELKLRMDREVLLVRAQLDEVTSENCALKDRLAVLQQDVKSLEEDVNNKRKKLEEMEKGYMKNREDEERLRKENSK------------------------------CREEVLDLSARNLQLSSENAELSSRLCTDQR-------------------------------------------------AVQTLTDRLAQVCQERDAAAVSSKQLQENLQQQENHGLRLQEQWRKEK----------------ELLERELQTAKEALQHLTVVESALTSQTLKNKSLEQDKESLLKETAENDQKLKKLQEALRNSETQIEQLNAQILTMWQEKDVHVQEAAAHIKMLQQSQDKVQELEERISQLRKEKEQVQHTHRLQEETAVSVLQNECKSLRVQNKELQNKVAQLQSRELELQRLTHECLTLRNKQAELETAKQEANQQAMRAESTRSMVQAQHTREIQELKEQMGSGTQEHASHLQTQLAEQQRRTQDFEDLLRSQAKQASVQMGLQQEQYEKLMASMQERMDEVEAKLKNTRVMLQEKVNQLKEQLAKNSKSDVLLKDLYVENSQLMKALQVTEQRQKSAEKKSFLLEEKVIALNKLLRKIAPASLTA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P11929-1", "uniprot_id": "NINL_DROME", "id": "P11929-1", "name": "Ninein homolog", "aln": "-MEVSADPYEQKLYQMFRSCETQ-CGLLDEKSLLKLCSLLELRDQGSALIASLGGSHQLG-VSFGQFKEALLNFLGSEFDGNTSSGFIERSLVITDEPLNNTYIE--------SPPE------SSDREVSPKLVVGTKKYGRRSRPQQGIYELSVTDSDNTDEDQ---------LQQQQNQRSLNGCDELGVQVQRSSSQSDLP-----GSRRLRSVHTSGSKLKRCASLPAR----------------RKMNSNTTG---------------ATTSPTAAAKLKQLSIQSQAQHSSSVESLDTVTPQQLETIS----------------VHSIMEAWELASIPNTRNLLHV--LGFDEEEEVNLQQLTKALEEELRGIDGDHEQSNMLRALAALQATELGNYRLAYRQQHEENLKLRADNKAANQRVALLAVEVDERHASLEDNSKKQVQQLEQRHASMVREITLRMTNDRDHWTSMTG----KLEAQLKSLEQEEIRLRTELELVRTENTELESEQQKAHIQITELLEQNIKLNQELAQTSSSIGGTPEHSPLRPRRHSEDKEEEMLQLMEKLAALQMENAQLRDKTDELTIEIESLNVELIRS-----------------------------KTKAKKQEKQEKQEDQESAATATKRRGDSPSKTHLTEESP-------RLGKQRKCTEGEQSDASNSGDWLALNSELQRS--------QSQDEELTSLRQRVAELEEELKAAKEGRSLTP---------------------------------------------------------------------------------------------------------------------------------------------------------ESRSKELETSLEQMQRAYEDCEDYWQTKLSEERQLFEKERQIYEDEQHESDKKFTELMEKVREYEEQFSK---------DGRLSPIDERD-------------------------------------MLEQQYSELEAEAAQLRSSSIQMLEEKAQEIS-------------------------------------------------------SLQSEIEDLRQRLGESVEILTGACELTSESVAQLSAEAGKSP----------------------ASSPISYLWLQSTIQEPAKSLADSKDEATASAIELLGGSPSHKTASRNNLTTSETSIFSTTPFESSQSGPSPTNSGNSNAYGANPGPAPISKPKRSQSPQQAAASEGE--------IADCETSSTASGKSFESNSKTSCLSHEKCSSPSALKEELKRLKFFELSLKEQIKDLSLQRDGLVMELQQLQEARPVLEKAYARTTHP----------------------------TLQQRLNQLELRNRHLQNVIKQQQHYTESLMQQSWRQHQVELNDLHSRIETQGVLLADQTQRLQSADILVKDLYVENSHLTATVQRLEQQRARVN-----LIHQQQQQQRLVGGGLPGMP--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * :* : : **:* * **.:.* ** * * : . *: * * : . *.* :***.:: .*. . .*. . . : .*:. * *: * . : . .*. .:* ::**: *.* . : * : .. . . . . . .: ::* .. :: . *:: : * ::: . . :.:.. :. ..:: * .* * *::*: *.*. :*.: * :** **::** . . : :* . *:. : * .*. * : * : *::* :. *:*: *:::*. .:.:::.*** . : : . : : . . *. :: *. :: *: .: . .** .*:.* :::: :*:.:* .. . :.* : : : ** .* :* : : * . . : :: . : :: . :* : : * . *:. : ..::.:: :. . : : *: .. : :.: : :. * ::. . . : .. .* .. . : .. . :. . . : : . . * : . . . ... . * . . . : . . :. : : .: : : : * . :. .:: . . . **: :. *: :* : : . : : : : :. * . . ::: . :: : : *.: . :: : * .* : :*:*:*:*****::* ::* *::: .: * .: ::*: *. ", "identical_positions": 113, "similar_positions": 309, "identity": "7.35%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-773", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96BY6-1", "uniprot_id": "DOC10_HUMAN", "id": "Q96BY6-1", "name": "Dedicator of cytokinesis protein 10", "aln": "MAGERTRRFTRSLLRPGQAAELRHSAASAAAVAVSSRQQQ--------------------RQEKPRLLEPLDYETVIEELEKTYRNDPLQDLLFFPSDDFSAATVSWDIRTLYSTVPEDAEHKAENLLVKEACKFYSSQWHVVNYKYEQYSGDIRQLPRAEYKPEKLPSHSFEIDHEDADKDEDTTSHSSSKGGGG------AGGTGVFKSGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMNFYKDEKISKEPKGCIFLDSCTGVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIHTLNRILQISP-EGPLQGRRSTELTDLGLDSLDNSVTCECTPEETDSSENNLHADFAKYLTETEDTVKTTRNMERLNLFSLDPDIDTLKLQKKDLLEPESVIKPFEEKAAKRIMIICKALNSNLQGCVTENENDPITNIEPFFVSVALYDLRDSRKISADFHVDLNHAAVRQMLL------------GASVALENGNIDTITPRQSEEPHIKGLPEEWLKFPKQAVFSVSNPHSEIVLVAKIEKVLMGNIASGAEPYIKNPDSNKYAQKILKSNRQFCSKLGKYRMPFAWAVRSVFKDNQGNVDRDSRFSPLFRQESSKISTEDLVKLVSDYRRADRISKMQTIPGSLDIAVDNVPLEHPNCVTSSFIPVKPFNMMAQTEPTVEVEEFVYDSTKYCRPYRVYKNQIYIYPKHLKYDSQKCFNKARNITVCIEFKNSDEESAKPLKCIYGKPGGPLFTSAAYTAVLHHSQNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDINAKANAKKKEALETSVGYAWLPLMKHDQIASQEYNIPIATSLPPNYLSFQDSASGKHGGSDIKWVDGGKPLFKVSTFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSNFIRSCKNLLNVEKIHAIMSFLPIILNQLFKVLVQNEEDEITTTVTRVLTDIVAKCHEEQLDHSVQSYIKFVFKTRACKERTVHEELAKNVTGLLKSNDSTTVKHVLKHSWFFFAIILKSMAQHLIDTNKIQLPRPQRFPESYQNELDNLVMVLSDHVIWKYKDALEETRRANHSVARFLKRCFTFMDRGYVFKMVNNYISMFSSGDLKTLCQYKFDFLQEVCQHEHFIPLCLPIRSANIPDPLTPSESTQELHASDMPEYSVTNEFCRKHFLIGILLREVGFALQEDQDVRHLALAVLKNLMAKHSFDDRYREPRKQAQIASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQGSRDDLSTNGGFQSQTA--IKHANSVDTSFSKDVLNSIAAFSSIAISTVNHADSRASLASLDSNPSTNEKSSEKTDNCEKIPRPLSLIGSTLRFDKLDQAETRSLLMCFLHIMKTISYETLIAYWQRAPSPEVSDFFSILDVCLQNFRYLGKRNIIRKIAAAFKFVQSTQNNGTLKGSNPSCQTSGLLSQWMHSTSSHEGHKQHRSQTLPIIRGKNALSNPKLLQMLDNTMTSNSNEIDIVHHVDTEANIATEVCLTILDLLSLFTQTHQRQLQQCDCQNSLMKRVFDTYMLFFQVNQSATALKHVFASLRLFVCKFPSAFFQGPADLCGSFCYEVLKCCNHRSRSTQTEASALLYFFMRKNFEFNKQKSIVRSHLQLIKAVSQLIADAGIGGSRFQHSLAITNNFANGDKQMKNSNFPAEVKDLTKRIRTVLMATAQMKEHEKDPEMLVDLQYSLANSYASTPELRRTWLESMAKIHARNGDLSEAAMCYIHIAALIAEYLKRKGYWKVEKICTASLLSEDTHPCDSNSLLTTPSGGSMFSMGWPAFLSITPNIKEEGAMKEDSGMQDTPYNENILVEQLYMCVEFLWKSERYELIADVNKPIIAVFEKQRDFKKLSDLYYDIHRSYLKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEYIYKEPKLTGLSEISQRLLKLYADKFGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFEEKEIEDRKTDFEMHHNINRFVFETPFTLSGKKHGGVAEQCKRRTILTTSHLFPYVKKRIQVISQSSTELNPIEVAIDEMSKKVSELNQLCTMEEVDMIRLQLKLQGSVSVKVNAGPMAYARAFLEETNAKKYPDNQVKLLKEIFRQFADACGQALDVNERLIKEDQLEYQEELRSHYKDMLSELSTVMNEQITGRDDLSKRGVDQTCT-RVISKATPALPTVSISSSAEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BZN6-1", "uniprot_id": "DOC10_MOUSE", "id": "Q8BZN6-1", "name": "Dedicator of cytokinesis protein 10", "aln": "MAGERTRRFTRSLLRPGQAAELRHSAASAAAVAVSSRQQQ--------------------RQEKPRLLDPLDYETVIEELEKTYRDDPLQDLLFFPSDDFSTATVSWDIRTLYSTVPEEAEHRAESLLVKEACKFYSSQWYVVNYKYEQYSGDIRQLPRAEHKPEKLPSHSFEVDHEDADKDEDTTSHSSSKGGGG------AGGTGVFKSGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMNFYKDEKISKEPKGCIFLDSCTGVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIHTLNRILQISP-EGPLQGRKSAELAELGLDPLDNCVTCECTLEETDSSENSLHPDFAKYLTETEDTVKTTRNMGRLNLFSLDPDIDTLKLQKRDSFENELMIKPFEEKAAKRIMIICRALNFNLQGCVTENEYDPVTNIEPFFVSVALYDLRDNRKISADFHVDLNHPAVRQMLS------------GTPPALENGNIDTGTPRQSEEPHIKGLPEEWLKFPKQAVFSVSDPHSEIVLVAKVEKVLMGNIGSGAEPYIKNPDSNKFAQKILKSNRQFCSKLGKYRMPFAWAVRSVFKDNQGNVDRDSRFSPLYRQESSKMSSEDLLKLVSDYRRADRISKMQSIPGSLDIAVDNIPLEHPNCVTSSFIPVKPFNVSAQSEPTVEVEEFIYDSTKYCRPYRVYKNQIYVYPKHLKYDSQKCFNKARNITVCIEFKNSDDDGAKPMKCIYGKPGGPLFTSSAYTAVLHHSQNPDFSDEVKIELPTQLHGKHHLLFSFYHITCDINAKANAKKKEALETSVGYAWLPLMKHDQIASQEYNIPIATTLPPNYLSIQDPTSAKHGGSDIKWVDGGKPLFKVSTFVVSTVNTQDPHVNAFFRQCQKREKDMSQSPTSSFVRACKNLLNVDKIHSIMSFLPIILNQLFKILVQNEEDEITATVTRVLADIVAKCHEEQLDHSVQSYIKFVFKTKSYKERTIHEELAKNLSDLLKSNDSTIVKHVLEHSWFFFAIILKSMAQHLIDTNKIQLPRAQRFPESYQSELDNLVMGLCDHVIWKCKEAPEETKRANHSVARFLKRCFTFMDRGFVFKMVNNYISMFSSGEFKTLCQYKFDFLQEVCQHEHFIPLCLPIRSANIPDPLTPSESIRELHASDMPEYSVTNEFCRKHFLIGILLREVGFALQEDQDIRHLALAVLKNLMAKHSFDDRYREPRKQAQIASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQGSRDDLSTNGGFQTQTS--MKHATSVDTSFSKDVLNSIAAFSSIAISTVNHADSRASLASLDSNPSTTEKSSEKTDNCEKIPRPLSLIGSTLRFDKLDQAETRSLLMCFLHIMKTISDETLIAYWQRAPSPEVSDFFSILDVCLQNFRYLGKRNIIRKIAAAFKFVQSTQNNGTLKGSNPSCQTSGLLSQWMHTTSGHEGHKQHRSQTLPIIRGKNALSNPKLLQMLDNSMNSNSNEIDIVHHVDTEANIATEVCLTILDLLSLFTQVHQRQLQQSDCQNSLMKRVFDTYMLFFQVNQSASALKHVFASLRLFVCKFPSAFFQGPADLCGSFCYEVLKCCNHRSRLTQMEASALLYFFMRKNFEFNKQKSIVRSHLQLIKAVSQLIADAGIGGSRFQHSLAITNNFANGDKQMKNSNFPAEVKDLTKRIRTVLMATAQMKEHEKDPEMLVDLQYSLANSYASTPELRRTWLESMAKIHARNGDLSEAAMCYIHIAALIAEYLKRKGYWKMEKICTPPLLPEDTQPCDSNLLLTTPGGGSMFSMGWPAFLSITPNIKEEGAMKEDSGMQDTPYNENILVEQLYMCVEFLWKSERYELIADVNKPIIAVFEKQRDFKKLSDLYYDIHRSYLKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEYIYKEPKLTGLSEISQRLLKLYADKFGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFEEKEIEDRKTDFEMHHNINRFVFETPFTLSGKKHGGVAEQCKRRTVLTTSHLFPYVKKRIQVISQSSTELNPIEVAIDEMSRKVSELNQLCTTEEVDMIRLQLKLQGSVSVKVNAGPMAYARAFLEETNAKKYPDNQVKLLKEIFRQFADACGQALDVNERLIKEDQLEYQEELRSHYKDMLSELSAIMNEQITGRDDPAKCGVERPYTTRVTSKGTAAVPVVSISSSAEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB40ECN0-1", "uniprot_id": "A0AB40ECN0_DANRE", "id": "A0AB40ECN0-1", "name": "", "aln": "MAAESTRRFTKSLLKPGSAAEIRQTASSAVRNATITKQHLLETAPLEEGMVISEPHSTVVMQEKPKLIDPLDYEAVISELEAEFREDPLQDLLLFPDLDFTVSTLPVERRTVKSTVPEGADEHAECLLVRQACQYFNSQLHIVQYKYDEYGGDYRMLPRKLCKAEKLPSHSFEIDNEDADKDEDTTSLSSSKGGGGGAGSGGGGGIGVFKSGWLYKGNFNSTVNNSITVRSFKRRYFQLTQLSDNSYIMNFYKDEKISKEPKGCIFLDSCTGVVQNNRLRKHAFELKMNEVTYFVLAAENEQDMDDWINTLNRILQISPPDGPAQDRKSTDMSDSKNEISDIPQNNVPVHKNEETTENEIHPELAKYISETEESSRAVRAEERLNLFSLDPDIPVLRSPRTETGES-SSVHPFDEKLGKRLMICCRSLNLTLQGCVNEADTEPTTNIEPFFVSVCLLDVREGRKVSADFHVDVNHELVRQMLNSSGNPGDQGSDVGNGAPLENG-LTSPVEKKPEDCQLGPDMEKWLCFPKQAIFSITNPHTDIVMVARVEKVLMGNISSGAEPYIKNTDSSKTVHKMLKSNKQFCSKLGKYRMPFAWSVRSVFKDNQGTVDRESRFSPLFKQESNKISTEDLIKLITEYRRAEKASKLQTIPGNLEINVDCVPMECPNCVTSSYVALKPFEDCSQHAPTVEIDEFLQDSSKFAQPYRVYKNHIYIYPKHLKYDSQKSFAKARNIAVCVEFRSSDEEHAKPLKCIYGKPGGPVFTTTACTTVLHHSQNPDFYDEVKIELPTHLHEKHHILFSFYHVTCDINAKTSSKKKEALELPVGYAWLPLLKDGRISSQDFSIPVSCTLPAGYLHIKEPSSTKNG-SDVKWVDGGKQIFKLSTLVLSTVYTQDPHLNRFFQQCQKREAEISQPPTSNFLNCLKGLLSMEKIHAIIRFLPVIFNQLFKVLTQNDSDEVTTSTTRVLIHILAKCHEENLDHYLHSYIKFVFKTEACGFRTIHEELAKGMTSDLKSNEQLVIRNVLKFSWFFLEIIVKSMAQHLLDSNKLKLPRPQRFPGTFQNRLETLIMTMSDHIYWKNKELAEETRSANMAIAFFVKRCFTLMDRGFTFKLISNYLNMITATDNKALCELKFEFIREVCNYEHFVPLSLPIPSARITDNAS---TEAQSTKVDFPEYSLTEDFCRKHFLSGLLLRELGLALQDEQDLRHIALACLKNLMAKHSLDARYATKEKQARIASLYLPLYGLILDNMPRFFLRDLFPICLTASDQGSRDDLSVGVGLAGQVTHVLRHGNSMDASFSKEVLNSITAFSSLAVSTANHADSRGSLISIESNPSNSDRNSEKMDACEKFARPQSLIGFGSRFDKLDQAETRSLLMCFLHIMKTISEEVMVSYWHRAIHQEISDFFNILELCLQHFRFLGKRHIARKLAAAVKLAQATQNNGTLKGSNVSYHSPGLLPQWILS--AQDGHRHARSQTMPIIRGKNALTNPKLLHMMETDG--NVAEGENFNPTDVEANLSTEVALTVLDVLDLFVRHHKKQLQHDEGQNSLMKKVFDTYLLFFQINQSTTTLRHVFTALRLFMQKFPSTFFQGKADVCGSLCYEILKCCNHRSSSTQTEAAALLYFLMRRNFEFTKGKCIVRSHLQVIKAVSQLIADAGIGGSRFQQSLAIINNFANGDTPLKNTTFPADVKDLTKRIRTVLMATSQMKEHEKDPEMLVDLQYSLANSYASTPELRRTWLESMAKIHVRNGDLSEAAMCYIHISALIAESLRRRGYWKSEKGRMSSVSKEGACVNNCSPLLTPQDGETSFSMGWAAFTNISPNVKEEGAMKEDAGTQDTPYTEDTLVEQLEMCVDYLWKSERYELIAEINKPVIVVFEKRRDFKRLSELYYDIHRSYLKVTEVVNSEKRLFGRYYRVAFYGQGFFEEEESKEFIYKEPKLTGLSEISQRLLKLYSDKFGADNVKMIQDSNKVNPKDLDPRFAYIQVTYVVPYFNEKEQLEKKTDFERHHNIDRFVFETPFTLSGKKHGDVEEQCKRKTILTTSSSFPFLKKRIEVVEQQSTEMNPIEVAIDEMSRKVSELKQLCNMEEVDMIRLQLKLQGSVSVKVNAGPMAYARAFLEEKNAKKYPDNQVKLLKEIFRQFAEACGQALSVNERLIKEDQFEYQSEMKAHYKDMLTELSAIMNEQIP-------------YTRQPGTERHSAI-----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.* *****:***:**.***:*::*:**. *. ::*: ****:*::*****:**.*** :*:*******:**. **:.:*:. : **: ***** *:.:** ***::**:::.** ::*:***::*.** * *** *.*********:*:*********** ******** .** *******************::******:********.**************************************:*******::********.*.***:**:********** :** *.*:*::::: : * . . :: :::**.:*.::***::***:: ::.* *********** .*: : : * ::**:** .**:** *::** .*****.* : :* **********.* *:*:.**:*******:** ***** * .**** : : . ::.*: :: *:** *****:**:::**::**:**::********.*********.**.* .:*:****:***************:**********.***:******::***.*:*:***:**:::****:: **:*:***.*:* ** :*:* *******::.:***: :* ****::**: **:*:.:*******:**:***********.* *****:**:**:.**:: ***:**********:**::* *:********** *********:** ***:******:*******:.:******* .********:*..:*:**::.**:: :**..** :::.:* *:* **:******* :**:**:*:*** *****:* **::***** ::**.***.*:.. *.**.::***:*: ***:*:*****:*.**:.**:*::.**** .*:******:*** ::*********.: **:******.::. ****:. :::**:.****: **:*******:*:**::***.**** ::*..*:.*:* :.**: ** *: ***: ** ::* *:*****:****:.**::.**:.*::: : *:**: **:*::***::***:**.*** **.*.* : : : *:****:*::******* *:****:*:***::**:**:*** *********:* ** .***:*****:****::******::*:**:*: :.:*:********.. *: *.: ::*..*:*:****:*****:****:*:**.******.** *::****..::.*** * ***:.** **** ************************* *.:::**:** *:****.**::***:**:****:* **:***.*:.*:*********** * ::.***.**: : .::**:: ****:*********:*****:*::. * * : .: .*.***::***.**:**:*.**.: *::***: : ******:*****:****:***:::*:***::****: ****:**** **:***:***:******** ** **:*****:**:****.* *.*******:*******************:**** *******. :**:.***:***************:*****************************************.***************:***** *:*:**** ** ..: *.: :.. ***. .* : *****.** .*:**:*********:* *****.*: ***** ***::***********::***:*.****:****:**:************:****************************.**:*********************:*********:**************::********.*:*:*** ::***** ****:****************.* *****:*:**** **::****:*:.*.***:***********:*****:***. **********************************.*********************:******.**********:***.*:::******:***::*****. * : :: .*: ", "identical_positions": 1442, "similar_positions": 510, "identity": "64.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-775", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D5Z5-1", "uniprot_id": "MSS51_MOUSE", "id": "Q9D5Z5-1", "name": "Putative protein MSS51 homolog, mitochondrial", "aln": "MAPRSRRRKHKKPPP-VIPMIEIPPTEVSPVSPALSKPGPSIDALGFISLDNNVPGLSQLILQKLNMKNYEEYKLVINGGTPVSSFGFRCQQEMFQKMEDTFRFCAYCKVLPHGLSNCKVLRHCKRCRNVYYCDTECQRSDWPAHRKVCRELRLVAVDRVMEWLLVTGDFVLPSGPWPWLPEDIQNWDTWFSMRGLQLESTLNALLGSHSMTMLWASLGRPRPDPDVLHGSLKRLMTDVLSRPLTLGLGLRTVAIDVGKTGGSTLHVVGASHVETFLIRSGDYDELGYMFPEHLGFHVIMVGVDVATDLLQSSSSLSLEP-GTIQLSGHRALYHDFWEEQIETGILAHPDLVAAFHPGFHASPGLMEAWLPTLLLLRDYEIPTLITVYSQQELEASLQILVNLDTHIIACGANPFASLKPEQVYSNPNKQPVYSSAYYIMFLGSSPAN-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4VC12-1", "uniprot_id": "MSS51_HUMAN", "id": "Q4VC12-1", "name": "Putative protein MSS51 homolog, mitochondrial", "aln": "MAPRSRRRRHKKPPSSVAPIIMAPTTIVTPVPLTPSKPGPSIDTLGFFSLDDNVPGLSQLILQKLNMKSYEEYKLVVDGGTPVSGFGFRCPQEMFQRMEDTFRFCAHCRALPSGLSDSKVLRHCKRCRNVYYCGPECQKSDWPAHRRVCQELRLVAVDRLMEWLLVTGDFVLPSGPWPWPPEAVQDWDSWFSMKGLHLDATLDAVLVSHAVTTLWASVGRPRPDPDVLQGSLKRLLTDVLSRPLTLGLGLRALGIDVRRTGGSTVHVVGASHVETFLTRPGDYDELGYMFPGHLGLRVVMVGVDVATGFSQSTSTSPLEP-GTIQLSAHRGLYHDFWEEQVETGQTHHPDLVAAFHPGFHSSPDLMEAWLPTLLLLRDYKIPTLITVYSHQELVSSLQILVELDTHITAFGSNPFMSLKPEQVYSSPNKQPVYCSAYYIMFLGSSCQLDNRQLEEKVDGGI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RC59-1", "uniprot_id": "F1RC59_DANRE", "id": "F1RC59-1", "name": "MYND-type domain-containing protein", "aln": "-------------------------------------------------MNDSNS---------------------VSDNKANKPVGFRSTKEMFEKMEESFKICAQCERLPSQVKGS--LKRCTRCLNVYYCSKECQKKNWPQHKHYCNKLRMAAVDRCVEWLIYKGDLPFPTKAWSRPANKVSGWNDWLSMQG-DLTARLEPILSGQNMADLWTNGCRPRPDEAELRESVWRVCSEFLSRPLTIGMGIRMFNLDP-YSRPLTVHVVGAAQNETLGARTTDLDELSHMFPGHQGLEVVMVGPEVVQGPIMRPPLRAFGPRGRVYISAYKGLYHEFWEEKVEKGEAAKPDLVVGFHPGFEGQ-EVSQDWFPTLLLLRDYNIPTLITMISEAERQSTLHMFMELEMYVKDTGSNPFSSLKPEQIPKSPNKSPIYANAHYISFQGLLEIKEEEEQH-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::. . :..... . .***. :***::**::*::** *. ** :... *::*.** *****. ***:.:** *:: *.:**:.**** :***: .**: :*: .*. .: :..*: *:**:* .* : *:.:* .: :: **:. ***** *: *: *: ::.******:*:*:* . :* : *:*****:: **: *. * ***.:*** * *:.*:*** :*. . .. .: * * : :*.::.***:****::*.* :****..*****... : : *:*********:******: *. * ::*:::::*: :: *:*** ******: ..***.*:*..*:** * * ", "identical_positions": 155, "similar_positions": 136, "identity": "33.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-778", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AGW5-1", "uniprot_id": "A0A8I6AGW5_RAT", "id": "A0A8I6AGW5-1", "name": "", "aln": "----------------------------------------------------------MVVPGPLALSLLLPSFTLLLSHLSTSQDITSEPSS---EQQLCTRREHPIVAFEDLKPWVSNFTYPGVRDFSQLALDPSRNQLIVGARNYLFRLSLANVSLLQATEWASSEDTRRSCQSKGKTEEECQNYVRVLIVSG-RKVFMCGTNAFSPVCSSRQVGNLSRAIEKINGVARCPYDPRHNSTAVISSQGELYAATVIDFSGRDPAIYRS--LGSGPPLRTAQYNSKWLNEPNFVAAFDIGLFAYFFLRENAVEHD-CGRTVYSRVARVCKNDVGG-RFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSAFHLPEQDLIYGVFTTNVNSIAASAVCAFNLSAISKAFNGPFRYQENPRAAWLPIAN-PIPNFQCGTLPETGPNENLTERSLQDAQRLFLMSEAVQPVTPEPCVTQDSVRFSHLVVDLVQAKDTLYHVLYIGTESGTILKALSTASRSLRGCYLEELHVLPPGRLEPLRSLRILHSARALYVGLSDRVLRVPLERCSAYLSQGACLGARDPYCGWDGKRQLCS-TLEDSSNMSLWIQN-ITACPVRNVTRDGGFGPWSPWKPCEHLDG-DNSGSCLCRARSCDSPRPRCGGLECLGPAIHIANCSRNGAWTAWSSWAQCSTSCGIGFQVRQRSCSNPAPRHGGRICVGKSREERFCNENTPCPVP------IFWASWGSWSKCSSNCGGGVQSRRRSCEN------GNSCPGCGVVRSPGWGAGCRETYRPGESETTFTPKEFKTCNPEACPEVRRNTPWTPWLPVNVTQGG--ARQEQRFRFTCRAPLPDPHGLQFGKRRTETRTCP-ADGTGACDTDALVEDLLRSGSTSPHTLSGGWATWGLWSSCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDAAEYQDCNPQACPVRGAWSCWTAWSQCSASCGGGHYQRTRSCTSPAPSPGEDICLGLHTEEALCATQACP--EGWSLWSEWGVCTEDGAQSRSRSCEELVPGPGACVGNSSQSRPCPYSEIPVILPASSVEETASCGGFSLIHLIVTGVSCFLGSGLLTLAVYLSCQHCQRQSQESTLVHPATPNHLHYK-----SGGTPKNEKYTPMEFKTLNKNNLIP-DDRATFYP--LQQTNVYTTTYYPSPLNKPNFRPEASPGQRCFPNS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60519-1", "uniprot_id": "SEM5B_MOUSE", "id": "Q60519-1", "name": "Semaphorin-5B", "aln": "----------------------------------------------------------MVVPGPLALSLLLSSLTLLVSHLSSSQDIASESSS---EQQMCTRREHPIVAFEDLKPWVFNFTYPGVRDFSQLALDPSRNQLIVGARNYLFRLSLANVSLLQATEWASSEDTRRSCQSKGKTEEECQNYVRVLIVSG-RKVFMCGTNAFSPVCSSRQVGNLSRTIEKINGVARCPYDPRHNSTAVISSQGELYAATVIDFSGRDPAIYRS--LGSGPPLRTAQYNSKWLNEPNFVAAFDIGLFAYFFLRENAVEHD-CGRTVYSRVARVCKNDVGG-RFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSAFHLPEQDLIYGVFTTNVNSIAASAVCAFNLSAISKAFNGPFRYQENPRAAWLPIAN-PIPNFQCGTLPETGPNENLTERSLQDAQRLFLMSEAVQPVTPEPCVTQDSVRFSHLVVDLVQAKDTLYHVLYIGTESGTILKALSTASRSLRGCYLEELHVLPPGRLEPLRSLRILHSARALFVGLSDRVLRVPLERCSAYHSQGACLGARDPYCGWDGKRQLCS-TLEDSSNMSLWIQN-ITTCPVRNVTRDGGFGPWSPWKPCEHLDG-DNSGSCLCRARSCDSPRPRCGGLECLGPSIHIANCSRNGAWTAWSSWAQCSTSCGIGFQVRQRSCSNPAPRHGGRICVGKSREERFCNENTPCPVP------IFWASWGSWSKCSNNCGGGVQSRRRSCEN------GNSCPGCGV--------------------------EFKTCNPEACPEVRRNTPWTPWLPVNVTQGG--ARQEQRFRFTCRAPLPDPHGLQFGKRRTETRTCP-ADGTGACDTDALVEDLLRSGSTSPHTLNGGWATWGPWSSCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDAAEYQDCNPQACPVRGAWSCWTAWSQCSASCGGGHYQRTRSCTSPAPSPGEDICLGLHTEEALCSTQACP--EGWSLWSEWGVCTEDGAQSRSRSCEELLPGPGACVGNSSQSRPCPYSEIPVILPASSVEETTSCGGFNLIHLIVTGVSCFLVSGLLTLAVYLSCQHCQRQSQESTLVHPATPNHLHYK-----GGGTPKNEKYTPMEFKTLNKNNLIP-DDRANFYP--LQQTNVYTTTYYPSPLNKPSFRPEASPGQRCFPNS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P283-1", "uniprot_id": "SEM5B_HUMAN", "id": "Q9P283-1", "name": "Semaphorin-5B", "aln": "MPCGFSPSPVAHHLVPGPPDTPAQQLRCGWTVGGWLLSLVRGLLPCLPPGARTAEGPIMVLAGPLAVSLLLPSLTLLVSHLSSSQDVSSEPSS---EQQLCALSKHPTVAFEDLQPWVSNFTYPGARDFSQLALDPSGNQLIVGARNYLFRLSLANVSLLQATEWASSEDTRRSCQSKGKTEEECQNYVRVLIVAG-RKVFMCGTNAFSPMCTSRQVGNLSRTIEKINGVARCPYDPRHNSTAVISSQGELYAATVIDFSGRDPAIYRS--LGSGPPLRTAQYNSKWLNEPNFVAAYDIGLFAYFFLRENAVEHD-CGRTVYSRVARVCKNDVGG-RFLLEDTWTTFMKARLNCSRPGEVPFYYNELQSAFHLPEQDLIYGVFTTNVNSIAASAVCAFNLSAISQAFNGPFRYQENPRAAWLPIAN-PIPNFQCGTLPETGPNENLTERSLQDAQRLFLMSEAVQPVTPEPCVTQDSVRFSHLVVDLVQAKDTLYHVLYIGTESGTILKALSTASRSLHGCYLEELHVLPPGRREPLRSLRILHSARALFVGLRDGVLRVPLERCAAYRSQGACLGARDPYCGWDGKQQRCS-TLEDSSNMSLWTQN-ITACPVRNVTRDGGFGPWSPWQPCEHLDG-DNSGSCLCRARSCDSPRPRCGGLDCLGPAIHIANCSRNGAWTPWSSWALCSTSCGIGFQVRQRSCSNPAPRHGGRICVGKSREERFCNENTPCPVP------IFWASWGSWSKCSSNCGGGMQSRRRACEN------GNSCLGCGV--------------------------EFKTCNPEGCPEVRRNTPWTPWLPVNVTQGG--ARQEQRFRFTCRAPLADPHGLQFGRRRTETRTCP-ADGSGSCDTDALVEVLLRSGSTSPHTVSGGWAAWGPWSSCSRDCELGFRVRKRTCTNPEPRNGGLPCVGDAAEYQDCNPQACPVRGAWSCWTSWSPCSASCGGGHYQRTRSCTSPAPSPGEDICLGLHTEEALCATQACP--EGWSPWSEWSKCTDDGAQSRSRHCEELLPGSSACAGNSSQSRPCPYSEIPVILPASSMEEATDCAGFNLIHLVATGISCFLGSGLLTLAVYLSCQHCQRQSQESTLVHPATPNHLHYK-----GGGTPKNEKYTPMEFKTLNKNNLIP-DDRANFYP--LQQTNVYTTTYYPSPLNKHSFRPEASPGQRCFPNS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA52K968-1", "uniprot_id": "A0AA52K968_DANRE", "id": "A0AA52K968-1", "name": "Semaphorin-5A", "aln": "-------------------------------------------------------MAAMVFWAGSLSFVGLVIFHLLFLPVVTSQTPSSPPDTPDPQPEECRRKMHPVTSYTALSPWLFSFSVPGVNYYSPLTLDLSRSQLIVGARNHLFRLSLSNISLLQATEWGVDETTRRSCQSKGKTEDECQNYVRVLLLNG-SRLFTCGTNAFMPVCVTRPVTDISSVLDSISGVARCPYDPRHNSTAMITESGEVYAATVTDFSSRDPIIYRS--LGNMPPLRTAQYNSKWLNDPHFISAYEVSRFTYVFLRENAVEQD-CGKTVFSRVARMCQNDIGG-RFLLEDTWTTFMKARLNCSRSGDVPFYYHELQSTFYLPEQDLIYGVFTTNVNSIAASAVCAFNLSAITQAFNGPFRYQENPRTSWLSTPN-PIPNFQCGTVNDSGPGANLTERSLQDAQRLFLMSDVVQPISTDPLVMQDNIRFSKLAVDIVQGRDTLYHVMYIGTEYGTIIKALSTNNKSLRGCYLEEMNILPGNTQEAILNLQILHSDRSLFVGLPSRVLKIPLERCSNYITEQDCLGARDPYCGWDRKEKRCT-TIEDSSNMSQWSQD-ITKCPERNLTQDGGFSDWSTWQACNHDDGGEGISTCQCRTRACDHPRPQCGGLKCVGANIEVANCSRNGGWTPWSSWAECSTSCGIGFEVRQRSCNNPSPRHGGRVCVGQAREERLCNEKNPCPVP------MSWVSWSAWSKCSVACGGGVQSRVRTCEN------GNTCPGCPL--------------------------EYRACNLDSCAEVRRTTPWTPWYPVNVTQLG--ARQEQRVRYTCRALLADPHDLQLGKRKIETRLCPTTDGAAACETDGLVEDLLRMGRPVTRVQGAAWASWETWSTCSKECSKGFRTRKRSCAAPDGKSTPFACSGAPVEYQDCNTQPCPVKGAWSCWSSWSQCSTSCGGGHHQRSRSCSNPAPAYSGDICIGLHTEEVLCNTHECE--GGWGAWSEWAECNGEGLQLRARTCEIS---PASCLGNSTDQRQCRPNESAVLSKGQ--KRSTNCGGFSLFHLVLTGACCFLGAVLLSILVYVYCQRLRKPPQESAVIHPSTPNHLHYKD----NSCAPKNDLYTPMEFKTLNKNNLLPPDESCNFFPSPLPQTNVYTTTYYPSPLGKYDFPSMDSP--CSFMHS--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTT0-1", "uniprot_id": "SEM5C_DROME", "id": "Q9VTT0-1", "name": "Semaphorin 5c", "aln": "-------------------------------------------------------MNMLILKLPKMFSQLWLLLILSLLTLEGPQPSTGSGYTT-KSSVDLLENDSRYISYQDLMSTAKRFYDPETTWYSEMLFDVARNQVIVGARDTLYRMSFD-LEPLERASWGATPSEIAMCQAKGQSERWCRNYVRVLHSYGENQLYACGTNAFQPSCSWRQMENLT-VTGVDSGVVKCPFHPQANSTSLLQSNGQLFVGTATDFSGSDVAILRTGVESNKRFLRTKQYNNNWLSGAQFVGSFEAGHFVYFLLRESAAEHMSCGKVIYSRVARVCKNDVGGGGQLLRDNWTSFLKARLNCSLPGEYPYYFDEIQGMTYAESESILYATFRTSGSSIFGSAVCAYNLSSINAAFDGPFKQQEHSDAAWKTVNTNQRSQFQCGTSSIG---------HWLESSRYQLMDEAVQPIGAEPLYHSKLEQFGRLALDIINTKTEQVHVLFVASSGNHIKKLSVKYDGDGVQTCLVELWQADDTGTSSLLNMAYLKVSDSLYLGTDLALTRIPAQHCSRHVSQSSCLNSMDPYCGWNELVERCMPQPQDSSVLQHWHQAPQITCPVLNAPIDGGWSTWSPWAVCQQHEQ--PDSNCQCRQRSCNNPQPQHGGATCEGISTQVTNCTQHGGWTEWSAWSPCSQTCGIAVKIRRRTCGNPRPAFGGRTCVGSEQSEMYCRHLPPCPVAKPQSVDGGWGPWGEWSECSAQCGGGFRMRRRECNDPAPLNGGMECPGCRL--------------------------DYEECNMQSCQEVRKLSAWTPWLTVTGSGNSSEPHMERRFRFVCRATSPDPSSVRIGLPKEESRNCH-ADGSCQRQVDHDSADSDAAD----------------WSPCSVSCGGGVQQRHRGRGSQSRVCNIHACP-AEEQLSSNSLDNELEHGEWGCWSEWSACSVTCGLGLRRRTRRCLAGHDR----LCQGRALEEQKCEMVPCEDFLGWSAWSEWSSCSSDGIRLRHRRCLVEQPGSMECRGAEFEKTACVPNECEETQTAS----TATLPIVIFVGLLFTVACCLATYRFTKKRFMLSAEEALNKTTTTTASFDTYPNQYSSLPTKDYYDQRPKRQSSFRMPAKTSNLGNGNGTLNRNNMHQN--NTPKVLAKTYIDCESGTIKRQSALNNCRSNIDDEKF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. : * . : .* :. : . :: * . * * . :* : :* : .*:*****: *:*:*: :. *: :.*. **:**::* *:****** * ::: ****** * * * : ::: . .**.:**:.*: ***::: ..*:::..*. ***. * * *: .. *** ***.:**. .:*:.::: . *.*.:***.*.*: **:.::*****:*:**:** **.*.**:*:******* .*: *:*:.*:*. : .:.::*..* *. .** .*****:***:*. **:***: **:. ::* . . .:***** ::.* **.:.***: .:* .. :*.:*.:*::: : **:::.:. . * * . . . * *: ..: .: *: :*::* : ::* ::*: : :: **.: ******: : * :*** :. * * ** * . ***:. **.* *:: : ..* ** *:*: *:*: ** * * .::**:::*.** **:*: ** :***..::*:*:*.** * .*** ***. :.* *.. ****. * .*. **:** ****.: * * *:: * * ** : ::. ** :.* ***: :.**** .*. : . .: *:*.*:.*** .** .:::* : *:* * :**: :.* . **.** .* *.: *:* . .* : .. . : :* *.**: ** **.:** * :*:* * :* * ** * * **. ****. *. :* : * * * . * * . :. * .* .. :: . :. *: * .*: : . . : .:. . . :: . : **: . **.: * ** * .* : .:. .:* :.** . .. . . . : .. ", "identical_positions": 318, "similar_positions": 329, "identity": "26.15%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-781", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96JW4-1", "uniprot_id": "S41A2_HUMAN", "id": "Q96JW4-1", "name": "Solute carrier family 41 member 2", "aln": "MTNSKGRSITDKTSGGPSSGGGFVDWTLRLNTIQSDKFLNLLLSMVPVIYQKNQEDRHKKANGIWQDGLSTAVQTFSNRSEQHMEYHSFSEQSFHANN-GHASSSCSQKYDDYANYNYCDGRETSETTAMLQDEDISSDGDEDAIVEVTPKLPKESSGIMALQILVPFLLAGFGTVSAGMVLDIVQHWEVFRKVTEVFILVPALLGLKGNLEMTLASRLSTAVNIGKMDSPIEKWNLIIGNLALKQVQATVVGFLAAVAAIILGWIPEGKYYLDHSILLCSSSVATAFIASLLQGIIMVGVIVGSKKTGINPDNVATPIAASFGDLITLAILAWISQGLYSCLETYYYISPLVGVFFLALTPIWIIIAAKHPATRTVLHSGWEPVITAMVISSIGGLILDTTVSDPNLVGIVVYTPVINGIGGNLVAIQASRISTYLHLHSIPGELPDEPKGCYYPFRTFFGPGVNNKSAQVLLLLVIPGHLIFLYTIHLMKSGHTSLTIIFIVVYLFGAVLQVFTLLWIADWMVHHFWRKGKDPDSFSIPYLTALGDLLGTALLALSFHFLWLIGDRDGDVGD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BYR8-1", "uniprot_id": "S41A2_MOUSE", "id": "Q8BYR8-1", "name": "Solute carrier family 41 member 2", "aln": "MTHSKGRPVTYKTSASPESGGGFVDWTLNLNTIQSDKFLNLLLSMVPVIYQKNQEDRHKKVNGIWQDGLSGAAQTFSKRSEPHLDYHEFSEQAFHSSSSGHTPASCSPKYDDYAGYNYCDGREASETTAMLQDEDLSSEGD-DVIVETSQRIPKESSGVMALQILVPFLLAGFGTVSAGMVLDIVQHWEVFKNVTEVFILVPALLGLKGNLEMTLASRLSTAVNVGKMDSPIEKWNLIIGNLALKQVQATVVGFLAAVAAIILGWIPEGKYYLSHSILLCSSSVATAFIASLLQGIIMVGVIVGSKKTGINPDNVATPIAASFGDLITLAILAWISQGLYSCLETYYYISPLVCAFFLALTPIWIIIAAKHPATRTVLHSGWEPVITAMVISSIGGLILDTTVSDPNLVGIVVYTPVINGIGGNLVAIQASRISTYLHLHSIPGELPEEPKGCSYPFRTFFGSGVNNKSAQVLLLFVIPGHLIFLYTIHLMKSGHTSLTVVFVVVYLFAAVLQVFTLLWIADWMVHRFWRKGKDPDSFSIPYLTALGDLLGTALLALSFHFLWLIGDRDGDVGD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4INZ3-1", "uniprot_id": "A0A0R4INZ3_DANRE", "id": "A0A0R4INZ3-1", "name": "Solute carrier family 41 member", "aln": "------------------------------------------MAMESVIEVNQGEGQ-----------LTSSLLSSSENS------HQLSPETGDLDRASSLTRVCSREPSESD--PLLSTAFYGATVNISQDEPHN-----------IQEMPSESIRAMVLQILFPFLLAGFGTVLAGMLLDVVQHWDVFRNVTEIFILVPPLLGLKGNLEMTLASRLSTAVNVGRMNCSREKWNLIKGNLALKQVQATVLGFLAALVASFLEWILKAELITNHVALLCGCSVVTAFTASLLQGILMVGVIIGSKKVGINPDNIATPIAASFGDLITLGLLAVISQGLYYCMEPYPYITYLVCLFFLCLTPMWVILSFHHPESQKLLFSGWEPVITAMVISSLGGLILDRTITNPKLDGLVLYTPVINGVGGNLVSIQASRIATYLHFQCPLGELPEDTKGCYCPCRYFCSKGPNGRSAQVLLTLVAPGHLVFIYTIYIIQGSQSPPTAVFIFFYIIAAFTQVLLLMSIADVMVHCLWRYGRDPDSFSIPYLTALGDLLGTALLALCFFLKSLVT--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* .** :: *.: *: : : *:.* *.:* :: . . . . ** : .: . . *. : *** . .:*.** *.****.********** ***:**:****:**::***:*****.*********************:*:*:.. ****** ************:*****:.* :* ** :.: .* ***..**.*** *******:*****:****.******:**************.:** ****** *:*.* **: ** ***.***:*:*:: :** ::.:*.**************:****** *:::*:* *:*:*******:*****:******:****::. ****::.*** * * * . * *.:****** :* ****:*:***::::..::. * :*:..*::.*. **: *: *** *** :** *:************************.*.: *: ", "identical_positions": 289, "similar_positions": 123, "identity": "50.35%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-783", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6UVM4-1", "uniprot_id": "KCNT2_RAT", "id": "Q6UVM4-1", "name": "Potassium channel subfamily T member 2", "aln": "----------------------------------------------MVDLESE----VPPLPPRYRFRDLLLGDQG------------WQNDDRVQVEFYMNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLSCLLYIIRVLLEKPSQ---------GN---------------------DWSHIFWVNRSLPLWGLQVSVALISLFETILLGYLSYKGNIWEQILRVPFILEIINAVPFIISIFWPTLRNLFVPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIG-KKLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDNAEACFILSSRCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRGQCVCLCCREGQQSPEQWQKTYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASFHAHKKFGVCLVGVRREDN-----KNILLNPGPRYIMNASDICFYINITKEENSAFKNQDQ------------------QRKSNVSRSFYHGPSRLP-------------------VHSIIASMGTVAIDLQDTSCRAASGP----------------------------------------------------TLALPSEG--------------------------------------------------------------------------------------------------GKELRRPSIAPVLEVADTSSIQTCDLLSDQ-------------------------------------------------------------------------------------SEDETTPDEETSSNLEYA-----------------------------------------------------------------------------------------------------------KGYPPYSPYIGSSPTFCHLLQEKVPFCCLRLD----KSCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGSIDNLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMISITRLLLGLDTIPGSGFLCSMKITEDDLWIRTYARLYQKLCSSTGDVPIGIYRTESQKLTTSESQISISVEEWEDT---------------------KDVKDPGHHRSIHRNSTSSDQSDHPLLRRKSMQWARRLSRKGPKHSGK----TAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEMNDHQSTLSYILINPSPDTRLELNDVVYLIRPDPLSYLP-----NSEPSRKNSICNAAVQDSREETQL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z649-1", "uniprot_id": "KCNT2_MOUSE", "id": "D3Z649-1", "name": "Potassium channel subfamily T member 2", "aln": "----------------------------------------------MVDLESE----VPPLPPRYRFRDLLLGDQG------------WQNDDRVQVEFYMNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLSCLLYIIRVLLEKPSQ---------GS---------------------EWSHIFWVNRSLPLWGLQVSVALISLFETILLGYLSYKGNIWEQILRIPFILEIINAVPFIISIFWPTLRNLFVPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIG-KKLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDNAEACFILSSRCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRG-------QEGQQSPEQWQKTYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASFHAHKKFGVCLVGVRREDN-----KNILLNPGPRYIMNASDICFYINITKEENSAFKNQDQ------------------QRKSNVSRSFYHGPSRLP-------------------VHSIIASMGTVAIDLQDTSCRATSGP----------------------------------------------------TLALPSEG--------------------------------------------------------------------------------------------------GKELRRPSIAPVLEVADTSSIQTCDLLSDQ-------------------------------------------------------------------------------------SEDETTPDEETSSNLEYA-----------------------------------------------------------------------------------------------------------KGYPPYSPYIGSSPTFCHLLQEKVPFCCLRLD----KSCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGSIDNLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMISITRLLLGLDTIPGSGFLCSMKITEDDLWIRTYARLYQKLCSSTGDVPIGIYRTESQKLTTSESQISISVEEWEDT---------------------KDVKDPGHHRSLHRNSTSSDQSDHPLLRRKSMQWARRLSRKGPKHSGK----TAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEMNDHQSTLSYILINPSPDTRLELNDVVYLIRPDPLSYLP-----NSEPSRKNSICNAAVQDSREETQL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UVM3-1", "uniprot_id": "KCNT2_HUMAN", "id": "Q6UVM3-1", "name": "Potassium channel subfamily T member 2", "aln": "----------------------------------------------MVDLESE----VPPLPPRYRFRDLLLGDQG------------WQNDDRVQVEFYMNENTFKERLKLFFIKNQRSSLRIRLFNFSLKLLSCLLYIIRVLLENPSQ---------GN---------------------EWSHIFWVNRSLPLWGLQVSVALISLFETILLGYLSYKGNIWEQILRIPFILEIINAVPFIISIFWPSLRNLFVPVFLNCWLAKHALENMINDLHRAIQRTQSAMFNQVLILISTLLCLIFTCICGIQHLERIG-KKLNLFDSLYFCIVTFSTVGFGDVTPETWSSKLFVVAMICVALVVLPIQFEQLAYLWMERQKSGGNYSRHRAQTEKHVVLCVSSLKIDLLMDFLNEFYAHPRLQDYYVVILCPTEMDVQVRRVLQIPMWSQRVIYLQGSALKDQDLLRAKMDDAEACFILSSRCEVDRTSSDHQTILRAWAVKDFAPNCPLYVQILKPENKFHIKFADHVVCEEEFKYAMLALNCICPATSTLITLLVHTSRG-------QEGQQSPEQWQKMYGRCSGNEVYHIVLEESTFFAEYEGKSFTYASFHAHKKFGVCLIGVRREDN-----KNILLNPGPRYIMNSTDICFYINITKEENSAFKNQDQ------------------QRKSNVSRSFYHGPSRLP-------------------VHSIIASMGTVAIDLQDTSCRSASGP----------------------------------------------------TLSLPTEG--------------------------------------------------------------------------------------------------SKEIRRPSIAPVLEVADTSSIQTCDLLSDQ-------------------------------------------------------------------------------------SEDETTPDEEMSSNLEYA-----------------------------------------------------------------------------------------------------------KGYPPYSPYIGSSPTFCHLLHEKVPFCCLRLD----KSCQHNYYEDAKAYGFKNKLIIVAAETAGNGLYNFIVPLRAYYRPKKELNPIVLLLDNPPDMHFLDAICWFPMVYYMVGSIDNLDDLLRCGVTFAANMVVVDKESTMSAEEDYMADAKTIVNVQTLFRLFSSLSIITELTHPANMRFMQFRAKDCYSLALSKLEKKERERGSNLAFMFRLPFAAGRVFSISMLDTLLYQSFVKDYMISITRLLLGLDTTPGSGFLCSMKITADDLWIRTYARLYQKLCSSTGDVPIGIYRTESQKLTTSESQISISVEEWEDT---------------------KDSKEQGHHRSNHRNSTSSDQSDHPLLRRKSMQWARRLSRKGPKHSGK----TAEKITQQRLNLYRRSERQELAELVKNRMKHLGLSTVGYDEMNDHQSTLSYILINPSPDTRIELNDVVYLIRPDPLAYLP-----NSEPSRRNSICNVTGQDSREETQL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T3C7-1", "uniprot_id": "A0AB32T3C7_DANRE", "id": "A0AB32T3C7-1", "name": "", "aln": "----------------------------------------------MDDRE------ATRFPLKHRFKDLLLREQ---------------NDPKFQVEFLVKESSFKERLQWYLIKNQRSSLSVRVFYLSLKVLSCILYVSRVLTDCKHQTQCSS--HHGNYTLLEI---------------DWAPVIWVDRNEILWAVQVSVAVICLFMRILLTYLRYRGNILQQVLQMAFILELIDTVPFVIGIFYQSFRKLFVPVFLNCWLAKRALESTVNDLHRAIHRTQSAMFNQVLMLISTIVCLIFTFICGVEHLQRAG-TKLTVFDSFYFCIVTFSTVGFGDVVPDIWPSKLLVVFMILVTLMVLPIQFEELAYLWMERQKSGGYYSRQRAETEKHVVLCVSSIKIDLLMDFLNEFYAHPKLEEHYVIILCPTELDAAVRSVLRIPMWSHRVIYLQGSALKDQDLVRAKLDYAEACFILTCRCVADRNAADYQTILRAWAVKDFAPGCTLFVQILKPENKFHVKFADHIVCEEEFKFAMLAMNCICPATSTFITLLVHTSQG-------LEGQHSPEDWHRIYGKCSGNEVYSIVLNKSIFFSEYEGNNFAYASFNAYNKYGICLIGVCPEDT-----KSILLNPGAQYTMNAMDTCFYISLTKEENSYVKQREC------------------GNNS---------KTQPP-------------------MGSAITRPGTMAIDIQEISIPSSLEP----------------------------------------------------SLSTGAN---------------------------------------------------------------------------------------------------TSERRQPIIIPVLELPDSPSFQASKLLSGQ-------------------------------------------------------------------------------------SKSHINGDE---SNDGYF-----------------------------------------------------------------------------------------------------------IGYPPNLPYIGSSTILCHLRKKKMPTCCMHLEKFLSKTCNHKDDEDAKVYSLKSKLVIVSVETAGNSLYNFILPLRASYRPQNELWPIVLLLEHVPDEEFLETISWFPMIYYLLGSIDSLDDLLRCGVSFAASMVVVDKESTMTAKEDYMADAKTIVNVQTLFRLFSGLNIITELTHSANMRFMQFSTKDCHSLAFSKLAKKEREKGSNLSFIFHLPFAAGRVFSISMLDTLLYQSFVKDYMITITRLLLGLETTPQSGFLCAMSITEEDLCIETYGRLYQRLSSTVGDIPIGIYRTKSQTVESPETPQFQMSDKASVF---------------------DEGGDLDEQHQNLQCEIPDSQLQTQSLRRRSMQWAS--SLLGPWHTER----EADRLSQHRGVLLSCSERLEVTELVKKRMKNLGLSTLGFDEQTNIKNSHAYILINPSSDTKLELNDIVYIIRKDTLSSKL-----DNN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8DY93-1", "uniprot_id": "A8DY93_DROME", "id": "A8DY93-1", "name": "", "aln": "MSQNLQVSYTALAMSDDNQTCSYSMPSVASPSLNHRLQRNVNFNEDLNDLAGYPPQQLPTAPAVRRFSKSIFQRPRSMSVWSDISRSSMRLDERVRVEYYVNENTFKERLQLYFIKNQRSSLRIRIADLFLKLLSCVLYIIRVILDKNPTFITCYGCEVGNKTEFIISAKLTEEEFQENPIINWDAILWVNRPTVLWVLQLLLAMVSLTQSLVLTYLGYKGNIWQQILSFHFILELVTTIPFALTIVHPPLRNLFIPIFLNCWLAKRSLENMFNDLHRAMQKSQSALSQQLTILSATLLCLVFTSVCGIQHFQRAGHRHLNLFQSTYYVVVTFSTVGYGDFVPDIWPSQLYMVIMICVALIVLPTQFEQLAFTWMERQKLGGSYSSHRAQSEKHVVVCSTTLHADTIMDFLNEFYAHPLLQDFYVVLLSPMELDTTMRMILQVPIWAQRVIYIQGSCLKDGDLARARMNEAEACFILAARNYADKTAADEHTILRSWAVKDFAPNVPQYVQIFRPEHKLHVKFAEHVVCEDEFKYALLANNCTCPGASTLVTLLLHTSRG-------QEGQQSPEEWHRLYGKCSGNEIYHIVLGDSRFFGEYEGKSFTYASFHSHRKYGVALVGVRPAELPEFYEETILLNPGPRHIMKKDDTCYYMSITKEENSAFVVNQNQTSDPTAAAKEGSGTGGGGGASSSASHHHTAATANPTTTITTTVQATTTTISTTFTSSTLLSASTTTATINATSTAAAAPPPVPSVCVRVPHSPSYDSGGGTTGTTHLQPYPYPQSYPQPHPPMQTPDSGEFASLFVPSENPTAVIISDSRQNLKDTTVTQTAATITTTTLPPPPQTMGSPSMAGGSGGCGGGGLGLGSAHSMGTSLSITPATLTTTGNHLDVPFANNPNLLSPDVLNQRRGSRRPSILPVPDMFTSSSFSIAGNDDGEEGDESDDEIDDEMPWRSPSEKIACLGGHFPQSRTYSLIMSSSEDSYQRGCSFCSATASASAAAVAVAVAAAPAPAPAPAYPSDSAGESGTNADSAAMPSEEYLPQLRRRVMKKSYSCDSECRSVPGMGMGMAMGVGLGGGTLARLAARRRQLQRCSSCSCSTATTTTTPAVAATTAMAAGSGATAFTSSSSVETRRPVRPVWVYDYSCIVKGFPPVSPFIGVSPTLCYLLKEKKPLCCLQLA----QVCEHCSYRNAKEYQWQNKTIILAADYASNGIYNFIIPLRAHFRSKTSLNPIILLLERRPDVAFLDALSYFPLVYWMLGSIDCLDDLLRAGITLAESVVVVNKELSNSAEEDSLSDCNTIVAVQNMFKFFPSIKSITELSQSSNMRFMQFRAHDKYALHLSKMEKREKERGSHISYMFRLPFAAGAVFSASMLDTLLYQAFVKDYVITFVRLLLGIDQAPGSGFLTSMRITKDDMWIRTYGRLYQKLCSTTCEIPIGIYRTQDTSNADTSHVSNSPVERWGPFSAFSRHCVRLRPSYDEETGTPDSTKDSTEMLRGVTYRPPGSATGGASSFRPQPQRQRSVNCLGGCSERKGSSYSINLADEARDNHAQQIERAEIANLVRSRMESLNLPTIDYDDVSEKRNHLSYVIINPSCDLKLEEGDLIYLVRPSPFSAQKTFERHNSRRKSNISFCSNINLGATCGPQMPQMNMNMANTAVGAGSRRGSGIAGLNPMQMQSVQTLAGYGSSSQRCSPPMQQIKSNSLSLPDSPTVVGNQRGRSNSLRIDNDILLRRSSSLRQGLPSVGVSHGRRKSSLEEIGISHFTTLMQATNHSNPIKISLNGSIGMENQISLQVTPPEEPTPMLGVPCMLGGGGGGGINPSGAGSSTGGMLGGGSSLAINTADLGPGPSTSSGASGSLQAQDSLGQQSSQVSSPQHLQGTIV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . * ** . :: * :.:**: ::*.:*****: ::******** :*: : **:***:**: **: : *. :* ::**:* ** :*: :*::.* ::* ** *:*** :*:* . ****:: ::** : *. .:*:**:*:********::**. .******::::***: :*: :* :*::**:** :**::*::* * :*.:*:* *: :*******:**..*: *.*:* :* ** *:*:*** ***:**: ****** ** ** :**::*****:* :::: * :*********** *::.**::*.* *:*. :* :*::*:*::****:***.*** ** **::: *******:.* .*:.::* :****:********. . :***::**:*:*:***:*:***:***:*:** ** **.:**::***:***:* ***:***:*:: **:*****:* *** .* **.****:.*:****:::.*:*:.*:** : :.******.:: *: * *:*:.:****** . .: * : * * : .* : :: * :: * :* :: *:* * ** :: :.*:. . ..: .:. . *. .. * *:** *:** *. :*:* ::* * **::* : *:* .:** * :.* :*::.: *.*.:****:**** :*.:..* **:***:. ** **:::.:**::*:::**** ******.*:::* .:***:** : :*:** ::*.:*** **.:*::*..:. ****::.:******* ::* ::* :**: *:*:*:**:::::*:****** *** *********:*****:*::.*****:: * **** :* ** :*: *.**.****:*.*:. ::*******:. . .. :. .. : . ... * . * . * : : : * ** *:::**:.**: *.*.*:.:*: .: :. :*::**** * ::* .*::*::* ..:: :.. ", "identical_positions": 471, "similar_positions": 362, "identity": "24.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-788", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D5P4-1", "uniprot_id": "ADAD2_MOUSE", "id": "Q9D5P4-1", "name": "Adenosine deaminase domain-containing protein 2", "aln": "MASVDE-----GGRRRPRLAASLQISP--GPWKPSGGQEPTEAG---DAAPRTAEHG------------VAGAQEAHREACKALGGSVLSPGPAGDFPGALHGLSMLPKDPPPAQAVALLTQCMANLGVSLTFLEDQTAGPGSSFSVCADLDGLVCPAGTGSSKLEAKQQAALSALQYIQKQLERPEPLVTPRQPLLTSLSIETILTHEQRCAAVVSAGLDRLLSESSPYQACKGTVAAVILEREVQGSIGHSKETYELVALGTGSSSCAGWLEFSGRRLHDCHGLVIARRALLRFFFRQLLLVTQGGPKGQERSVLTPQPGPGPPFALKPGVFLHLYVSNTPKGAAHDIYLPLASEDSVLHSPAFRLQAHVCGQLKPVSYVAPALRDTHVGCLSASDKLARWAILGLGGGLLAHFLPPLYATSLVLADPCHDPSTLNRVIHSRPRLDSVLGSCLPCPYVRTTLHLFAGPLVAPSDPGPSTCHSLSLNWSLGDPDIEVVDVATGRVKTD----SSVGPPSRLCKAAFLSAFRQVARALEKPQLLSLQTYEAAKAVP--YREARQQLSLLLDQQGLGAWPSKPLVGKFRH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCV1-1", "uniprot_id": "ADAD2_HUMAN", "id": "Q8NCV1-1", "name": "Adenosine deaminase domain-containing protein 2", "aln": "MASASQGADDDGSRRKPRLAASLQISPQPRPWRPLPAQAQSAWGPAPAPATYRAEGGWPQVSVLRDSGPGAGAGVGELGAARAWENLGEQMGKAPRVPVPPAGLSLPLKDPPASQAVSLLTEYAASLGIFLLFREDQPPGPCFPFSVSAELDGVVCPAGTANSKTEAKQQAALSALCYIRSQLENPESPQTSSRPPLAPLSVENILTHEQRCAALVSAGFDLLLDERSPYWACKGTVAGVILEREIPRARGHVKEIYKLVALGTGSSCCAGWLEFSGQQLHDCHGLVIARRALLRFLFRQLLLATQGGPKGKEQSVLAPQPGPGPPFTLKPRVFLHLYISNTPKGAARDIYLPPTSEGGLPHSPPMRLQAHVLGQLKPVCYVAPSLCDTHVGCLSASDKLARWAVLGLGGALLAHLVSPLYSTSLILADSCHDPPTLSRAIHTRPCLDSVLGPCLPPPYVRTALHLFAGPPVAPSEPTPDTCRGLSLNWSLGDPGIEVVDVATGRVKAN----AALGPPSRLCKASFLRAFHQAARAVGKPYLLALKTYEAAKAGP--YQEARRQLSLLLDQQGLGAWPSKPLVGKFRN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1D5NSL4-1", "uniprot_id": "A0A1D5NSL4_DANRE", "id": "A0A1D5NSL4-1", "name": "", "aln": "MANHGVS---TEGKRLPRMAATLMMRFASEREPTFGIHRASLRP---------------------------LTPNSEIEDSRSAGEESQSTNPELHCLDDVEGQSSVGHQTQEVQSPDSPPQ-MEDLG--------------------------------SSSDVTSLSGWSLSSVTAPEATVDLLEDATDGSLTRDQRTGVKFADWHKNRVTALCTGRFDKLLRECPEYHSTKSCFAAFVLEREVRDTGGQRCENYEVVALGSGQSCCSGWLSYTGSVVHDCHAIVIARRALKRYLYKQLLLFYSADPDMKQRSILESVPAER-LLQLKPHIYLHLYTNKTPKGAAQCIVLSQNS-----AYSALKLQCHAKGSLIPAAFLLPSVWGARTCCMSDSAKLTRWTVTGLQGALLSHFINPVYITSFVLGDSRHCSEKVSEIINKR--LGTGWTDALPPPFKQTSIFFLSGENVGPGE-NNEYCKDLSVNWCLGDSSIEILDSTTGYAINNSPFVSGPGSSSRLCKRALYFCFRKLAGLAGHHELLSFTTYRSAKMAAQLYQETKTQVNMQFLTNNAGPWNSKHLVDCFSR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. . .:* **:**:* : . : : : .. .:: . . * * ::. *: .: .** ..*. : . :**:: . :: * . .:: *::* :*: :. :* ** * . * : *. .*..:****: : *: * *::****:*.*.*:***.::* :****.:******* *::::**** ...*. :::*:* . *. : *** ::**** .:******: * *. * ..::**.*. *.* *..:: *:: .::. *:* * **:**:: ** *.**:*:: *:* **::*.*. * . .:.. *:.* *.: .** *: :*::.:::* *.*.: . *:.**:**.***..**::* :** . : :. *..***** :: .*:: * : **:: **.:** . *:*:: *:.: : :. *.* ** **. * .", "identical_positions": 155, "similar_positions": 180, "identity": "26.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-791", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LNU9-1", "uniprot_id": "A0ABK0LNU9_RAT", "id": "A0ABK0LNU9-1", "name": "", "aln": "--------------------------------------------------------------MSSPSLSDLGKREPGAAGADERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFILNEGVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYEGQKLLDSLAETWDFFFSDVLPTLQAIFYPVQGKEPSVRQLALLHFRNTITLSVKLEDALARSHACVPPAIAQMLLVLQGVHESRGVTEDYLRLETLIQKVVSPYLGTYGLYSNE-GPCTHSCILEKRFLR-RSRSGDILAKNPVVRSKSYNTPLLNPVAEHEAEGTASGGTSIRRHSVSEMTSCPEPQGFVDTPD------------------QGPSG--TFRSSPSPHSGPCPSRLYPPAHSPEQG--PDHGSPP--TSSPETLVDQILESVDSDSEGIFIDFGRGSRSSVSDFEAAGGRPSVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q812A5-1", "uniprot_id": "PRR5_MOUSE", "id": "Q812A5-1", "name": "Proline-rich protein 5", "aln": "-----------------------------------------------------MRTLRRLKFMSSPSLSDLGKREPGAAGTDERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFILNEGVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYEGQKLLDSLAETWDFFFSDVLPTLQAIFYPVQGKEPSVRQLALLHFRNTITLSVKLEDALARSHARVPPAIAQMLLVLQGVHESRGVTEDYLRLETLIQKVVSPYLGTYGLYSNE-GPCTHSCILEKRFLR-RSRSGDILAKNPVVRSKSYNTPLLNPVAEHEAEGTAASGTSIRRHSVSEMTSCPEPQGFVDTPG------------------QGPSG--TFRSSPTPHSGPCPSRLYPPAHSPEQG--PGHGSPS--TSSPETLVDQILESADSDSEGIFIDFGRGSRSSVSDFEAPGGRPSVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P85299-1", "uniprot_id": "PRR5_HUMAN", "id": "P85299-1", "name": "Proline-rich protein 5", "aln": "-----------------------------------------------------MRTLRRLKFMSSPSLSDLGKREP-AAAADERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFSLNEGVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYEGQKLLDSLAETWDFFFSDVLPMLQAIFYPVQGKEPSVRQLALLHFRNAITLSVKLEDALARAHARVPPAIVQMLLVLQGVHESRGVTEDYLRLETLVQKVVSPYLGTYGLHSSE-GPFTHSCILEKRLLR-RSRSGDVLAKNPVVRSKSYNTPLLNPVQEHEAEGAAAGGTSIRRHSVSEMTSCPEPQGFSDPPG------------------QGPTG--TFRSSPAPHSGPCPSRLYPTTQPPEQGLDPTRSSLP--RSSPENLVDQILESVDSDSEGIFIDFGRGRGSGMSDLEGSGGRQSVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NZ01-1", "uniprot_id": "A0A8M1NZ01_DANRE", "id": "A0A8M1NZ01-1", "name": "", "aln": "MKRGSGNLWITMLENLSGGHSDRPSSRSSSTFSFSSLFALPHHLHMDGSSHPFRRTLYRLKLVSSPNLSQLGKSEK--ASLEERGSG-----PNATWNSIHNAVIAVFQKKGLADNELYTLNEGVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYEGQKLLDSLAETWDFFFCDVLTMLQAIFHPVQGKEPSVRQLALLHFRNTITLNMKLDEALSRPRARVPPSIVQMLLVLQGVHESKGVSEEYLKLESLLQKVVSPYLGTQGLCSHECGASHCSCFIERRLQYCWSKSADLPSTNPVVRSKSYNIPMLTPVAEYDSEVSSVGSVGIRRHSACDVTSCIEHQGYSALSVGIETSSTPRLSLDHDLMMRGAAGQPSLISPPVFIHTSTGCLHAPDAQIASSESEKVVSSPPSCSSSPETIVMQGLDSLESDPEGIFIDFSHCR----SDSFGTSRKTS--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***.**:*** * *. :***: .*********.******:***.*:**: *********************************************************.***. *****:*******************:***.:**::**:*.:* ***:*.************:**:*:**:**:*:********** ** * * *. **::*:*: *:*.*: :.********** *:*.** *:::* :: ....*****..::*** * **: . :*.:* :: *.* . . * :: ... .* . ****.:* * *:* :**.*******.: ** ... : * ", "identical_positions": 226, "similar_positions": 84, "identity": "48.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-794", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N5V2-1", "uniprot_id": "NGEF_HUMAN", "id": "Q8N5V2-1", "name": "Ephexin-1", "aln": "METRESEDLEKTRRKSASDQWNTDNEPAKVKPELLPEKEETSQADQDIQDKEPHCHIPIKRNSIFNRSIRRKSKAKARDNPERNAS------CLADSQDNGKSVNEPLTLNIPWSRMPPCRTAMQTDPGAQEMSESSSTPGNGATPEEWPALADSPTTLTEALRMIHPIPADSWRNLIEQIGLLYQEYRDKSTLQEIETR-RQQDAEIEDNTNGS-PASEDTPEEEEEEEE--EEEPASPPE---RKTLPQICLLSNPHSRFNLWQDLPEIRSSGVLEILQPEEIKLQEAMFELVTSEASYYKSLNLLVSHFMENERIRKILHPSEAHILFSNVLDVLAVSERFLLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEKAAFRELIAQLELDPKCRGLPFSSFLILPFQRITRLKLLVQNILKRVEERSERECTALDAHKELEMVVKACNEGVRKMSRTEQMISIQKKMEFKIKSVPIISHSRWLLKQGELQQMSGPKTSRTLRTKKLFHEIYLFLFNDLLVICRQIP-GDKYQVFDSAPRGLLRVEELEDQGQTLANVFILRLLENADDREATYMLKASSQSEMKRWMTSLAPNRRTKFVSFTSRLLDCPQVQCVHPYVAQQPDELTLELADILNILDKTDDGWIFGERLHDQERGWFPSSMTEEILNPKIRSQNLKECFRVHKMDD-PQRSQNKDRRKLGSRNRQ--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CHT1-1", "uniprot_id": "NGEF_MOUSE", "id": "Q8CHT1-1", "name": "Ephexin-1", "aln": "METKNSEDWGKPQRKSESSSRKSNHGPAEMRPALPPENREAPETGEETQNEEPRRLIPIQRHSLFNRAVRHR--HKARSTSERRAS------DQADLPKMGKSVNERSAFNLPQGRLSPWRTPAQRDTGAQEASESSSTPGNGTTPEECPALTDSPTTLTEALQMIHPIPADSWRNLIEQIGLLYQEYRDKSTLQEIETR-RQQDAEIQGNSDGS-QVGEDAGEEEEEEEEGEEEELASPPE---RRALPQICLLSNPHSRFNLWQDLPEIQSSGVLDILQPEEIRLQEAMFELVTSEASYYKSLNLLVSHFMENERLKKILHPSEAHILFSNVLDVMAVSERFLLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEKAAFRELIAQLELDPKCKGLPFSSFLILPFQRITRLKLLVQNILKRVEERSEREGTALDAHKELEMVVKACNEGVRKMSRTEQMISIQKKMEFKIKSVPIISHSRWLLKQGELQQMSGPKTSRTLRTKKLFREIYLFLFNDLLVICRQIP-GDKYQVFDSAPRGLLRVEELEDQGQTLANVFILRLLENADDREATYMLKASSQSEMKRWMTSLAPNRRTKFVSFTSRLLDCPQVQCVHPYVAQQPDELTLELADILNILEKTEDGWIFGERLHDQERGWFPSSMTEEILNPKIRSQNLKECFRVHKMED-PQRSQNKDRRKLGSRNRQ--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FDB4-1", "uniprot_id": "E7FDB4_DANRE", "id": "E7FDB4-1", "name": "", "aln": "MMAMTALFRGK---------WGHNNKPQEVQTKPRTPVPQLPSEDDENEDETLR--APIRRNSRFYRSMRKKKSAGPSEQQESPSSSPKPTVDPASYNRLSPAAANRVPLSPRLQKSPPSRSGISLLSNGVQGGVRSRSP--LASPGDWPRRLEM-EELSERTTSACTMQDNDNHSTADPDNITFRLVRNGDSPQKMAVENSCHNLNIMKNVDVLYQEYRDTSKQQEIDQRRQRDGLPTAGSGVLAAPALQLQLRSSTNS-LNLWQNLDAVKKSGLLQTLEPKEIILQEAMFELVTSEASYYKSLELLETHFLRNPLLVNTLSQSDMHFLFSNITDIMKASEKFLMDLEHRIEESILISDVCDIVHFHAVNHFQVFISYVINQVYQETNYRRILQENCAFRENMAILENQPKVKGLSFTSFLILPFQRITRLKLLVQNILKRVEENSEKERTAILAHQELEKIVKQCNEGARKMSRTEELISIEKTLEFKSKSVPVISHSRWLLKKGEVQQMSGPKSTRTMRSRKLYHPIYLFLFNNLLLITKRNSSGDKFQVLDSCSRSMLRTEDLEDQGQMLACVFVLKLLENQEDREVSYMLKTESVSDKLRWICALTPNRRTRFLSTSTHEPDSPQVQCIQSYSSQEPDELSVEMADVLHILECTDDGWILGERLHDGERGWFPNRVVERIMSAEVRAQNLKECQRIQQAQEGAQGTRAASRGRVAVRNSQYNASWTDL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : * :: * :::. . : .. .:: ::: : **:*:* * *::*:: . . * :* *. . :. : .:. : .* *: . ... : . * :* ::* : * : *:* .: :. :. : .: :: *: .: *:: .. :: :* * : .*: :::* ::. .: .:. . . *: * *..:* :****:* ::.**:*: *:*:** *******************:** :**:.* : : * *: *:****: *:: .**:**::****:**.*:********: :*.:**.*:*:** **.*** .*:::***:.**** :* ** :** :**.*:**************************.**:* **: **:*** :** ****.*******::***:*.:*** ****:*********:**:*******::**:*::**:: *******:**:* :: . ***:**:**..*.:**.*:****** ** **:*:**** :***.:****:.* *: **: :*:*****:*:* ::: *.*****::.* :*:****::*:**:*:**: *:****:****** ******. :.*.*:..::*:****** *::: :: .* :: .* ::. ** * ", "identical_positions": 310, "similar_positions": 224, "identity": "42.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-795", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C7U3-1", "uniprot_id": "ZH11B_HUMAN", "id": "P0C7U3-1", "name": "Probable palmitoyltransferase ZDHHC11B", "aln": "-----------------------------------------------------------------------MDTRSGSQCSVTP-EAIRNNEELVLPPRISRVNGWSLPLHYFRVVTWAVFVGLSLATFRIFIPLLPHSWKYIAYVVTGGIFSFHLVVHLIASCIDPADSNVRLMKNYSQPMPLFDRSKHAHVIQNQFCHLCKVTVN-KKTKHCISCNKCVSGFDHHCKWINNCVGSRNYWFFFSTVASATAGMLCLIAILLYVLVQYLVNPRVLRTDPRYE----------------------------------------------------------------------DVKNMNTWLLFLPLFPVQVQTLIVVIIRMLVLLLDLLGLVQLGQLLIFHIYLKAKKMTTFEYLINTRKEESSK----------------HQAVRKDPYVQMDKGFLQQGAGALGSSAQGVKAKSSLLIYKCPC---HFCTSVNQDGD-----------------------------------------SKAQEADDAPSTSTLGLQQETTEPMKTDSAESED-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9H8X9-1", "uniprot_id": "ZDH11_HUMAN", "id": "Q9H8X9-1", "name": "Palmitoyltransferase ZDHHC11", "aln": "-----------------------------------------------------------------------MDTRSGSQCSVTP-EAILNNEKLVLPPRISRVNGWSLPLHYFQVVTWAVFVGLSSATFGIFIPFLPHAWKYIAYVVTGGIFSFHLVVHLIASCIDPADSNVRLMKNYSQPMPLFDRSKHAHVIQNQFCHLCKVTVN-KKTKHCISCNKCVSGFDHHCKWINNCVGSRNYWFFFSTVASATAGMLCLIAILLYVLVQYLVNPGVLRTDPRYE----------------------------------------------------------------------DVKNMNTWLLFLPLFPVQVQTLIVVIIGMLVLLLDFLGLVHLGQLLIFHIYLKAKKMTTFEYLINNRKEESSK----------------HQAVRKDPYVQMDKGVLQQGAGALGSSAQGVKAKSSLLIHKHLC---HFCTSVNQDGDSTAREGDEDPCPSALGAKARNSRLICRRLCQFSTRVHPDGGSMAQEADDAPSISTLGLQQETTEPMKTDSAESED-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1M6X9-1", "uniprot_id": "F1M6X9_RAT", "id": "F1M6X9-1", "name": "Palmitoyltransferase", "aln": "--------------------------------------------------------------------MKEMSTCGIGQNRVLP-EAQENNVKKLLPRPLSRVNGWSPPLHSFQAISWTTYLAMSIVTFGIFIPFLPTSWKYAANAVMGGVFMFHLVVHLIAITIDPADTNVRLKKDYLEPVPTFDRSKHAHVIQNQYCHLCEVTVS-KKAKHCSSCNKCVSGFDHHCKWLNNCVGKRNYWFFFFSVASAAFGLLGVLIILLYIFIQYFVNPNGLRMDPLYKGAAVWIGAGWTC-----------------------------------------------------LSVFIEISSENTWLLFLSLSPVPVKTPVVLSIAAMVLLLAIASFVLLGHLLVFHFYLISKKLSTFDYMMQTRFQKSP-----------------RPAEKKELPPRKKGNVSQE------KSNNLTWPTSPTRPRVEPQ---RLLLST---------------------------------------------------------LSPQSNECFMAPAPKTPPQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14AK4-1", "uniprot_id": "ZDH11_MOUSE", "id": "Q14AK4-1", "name": "Palmitoyltransferase ZDHHC11", "aln": "--------------------------------------------------------------------MKEMNICGINKNWVLP-EAQENNVKKFLPRPLSRVNGWSPPLHSFQAISWITYLAMSIVTFGIFIPFLPYSWKYAANIVMGGVFIFHLIVHLIAITIDPADTNVRLKKDYTQPVPAFDRSKHTHVIQNQYCHLCEVTAS-KKAKHCSACNKCVSGFDHHCKWLNNCVGRRNYWFFFWSVASAAVGILGVMIILCYICIQYFVNPDELRTDPLYK----------------------------------------------------------------------EIISENTWLLFLSLWPVPVKTPIVLSIAVMALLLAIASFVMLGHLLIFHLYLITKNMSTFDYLMKTRFKKNL-----------------HPAEEKELPLQKKGDLPQE------KSDNWAWPKSP--PRVGSQ---KFPVST---------------------------------------------------------LSPKSSVCFVASPPKICHSED-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7EZI4-1", "uniprot_id": "ZDH11_DANRE", "id": "E7EZI4-1", "name": "Palmitoyltransferase ZDHHC11", "aln": "--------------------------------------------------------------------MTNLNCFGRHRRRTAPHNATGSRSELVAPPIHSRINGWSSPLHSFQFIALLIFSFMAIVAFGIYVPLLPAPWSYAAYALIGSAFVLHLFSHVTAVTIDPADVNVRRRKDYSSPMPTFDNSKHPHVIDNLHCTLCEVDVS-PKAKHCSTCNKCIADFDHHCKWLNNCVGGRNYWFFFTAVSSAVIGVILLIPLVLFVFIEHYVNPAVLRTAPQFQ----------------------------------------------------------------------TVKGNGTWLVFLPVAPVETSSISLLVVSFITALLSLAALLLLCHLLCFHIYLLSQGISTYEYIVRKRQSPNPKEKQQVPPALPSNGATAQSLELQEPPLNCDAPLSSR-SCTFKLEDRGPMPEPICAEMEEASGEHHLSYSSESATQKIAG-----ESVMSLPVVWSLSETERPQASQVEVKPLEGRPVVQDPLGSSIMDTALVHQQLMTEQPQYLHFKQKMP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPM2-1", "uniprot_id": "Q9VPM2_DROME", "id": "Q9VPM2-1", "name": "Palmitoyltransferase DHHC domain-containing protein", "aln": "MSTTAAGLKSGPKGAYGVRSETDHIITISTAGLTESHSESPAKGVVTPVRKPHSLGSEDSPENIIPGEQAETNKKPLHLCRLSQLVSYQSNIADVQHRKGRRLHGLQLPLHPLQIFGWLVLLLFGVASYWVLIPAFHARIQGPLYGLITGLYLVHIASHLTALLTDPADKELRRVHRNDRIVPEFDRSKHSHVIENGRCHLCNIRTSSNRTKHCSVCNKCVGKFDHHCKWLNHCIGSRNYVAFLMCVVSAVVATLVIVAAVVAQIVFYYIQPDWLSFYWCPTESSHTIESGDFINITLSLSNGTMMLIEQHTSEEDVHQEMWDEEQANMTISTLPTLLENFTAIIEASATRPGISPTNHTETQPVVTGIGLNETIFMFLLGVLGLLAAVSAGLLLHLCFFHIYISFLGLTTYEYIRNHRQAQDAKTKQLLEG-------APGVRAPKNGNVHFSASLPEPHNPSKSLPGGQQLYCCSSAPHPSQHSQESVGQTEQSLRLHCCASSREFHQSGQAIYVCSLLEEAVPQIQVEPDTLSSFHCCSSFAASSLQRRVSLAKGSLISAEPRHLRPATYLQYTEQCTLCTFRLRRGSGPGTGSSGAVSSAGGSSSTRTLTSQTGGSSASATAAGNISKHQRWRRKWNCCAAVPDSPDLPNDLLAALTFRESEEAAAAAKLNAQELPIQFIRTLNGGLDQELPLKATTATPTPPRSSRLRYMLRLLGRYRRPRCRHGAHHGIAAKEHQNIGGSAIKQNQIRPLQLQAAGRGYANSTATPTPPASSPSRSSLESSDLSTSTSPSCGKKELMLLPTSVIRDDSVTTYTLTLPPALPPPTRRKMNQTTQELAELAETLGFASNLQHSQHNSQTNSRTLPSFGNVYRRQRRKHFLRTRSPTLSPIHESGLSNPTSPQPLRHHHQNLANSNSNPAKAMSSPMLNRNSGSANSSALLVQNLCSLAGETLRNSASNSSLQSLSSNSSST", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .. . *::* . *** :: . :. .:: : :* : . : . : .*: *: * **** ::* : :* **.***.***:* * **:: .. ::*** ****:. *******:*:*:* *** *: * **. . : :: : : : ::* * : . : : . .: : : ** . * :* **:*: ::*::*: . * . :: . . . . . : . : : ", "identical_positions": 63, "similar_positions": 86, "identity": "6.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-796", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1AWN4-1", "uniprot_id": "AT10B_MOUSE", "id": "B1AWN4-1", "name": "Phospholipid-transporting ATPase VB", "aln": "---------------------------------------------------------------------------------------------------------------------MTCSLDFSWLRWKWR--------------TQDGFSQSPSETTPLLSP----ETDRQSHNTA-----------------------------------------------EQRVVYPNNSMCHQD--WKKVCRRYPGNSICTTKYTLLTFLPQNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITIFPLATVLLIIMVKDGIEDFKRYCFDREMNSASIQIYERKEQRYMLKRWQDVRVGDFVQMQCNEIVPADILLLFSSDPSGVCHLETANLDGETNLKQRRVVKGFSQPEVQFQPEHFHSTIVCEKPNNHLSKFKGYMEHPDQTRTGFGSESLLLRGCTIRNTEVAAGIVIYAGHETKAMLNNSGPRYKRSKIERRINTDIFFCIGLLFLMCLIGAVGHSLWNGTFKEHPPFDVPDADGNFLSLALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFLLHNDLDLYDEETDLSIQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTIVGSEYCHQENAKRLEMPKELDSDGEEWTQYQCLSFPPRWAQGSTTMRSQGGAQPLRRCHSARVPIQSHCRQRSVGRWETSQPPVAFSSSIEKDVTPDKNLLSKVRDAALWLETS-DTRPAKPSHSTTASIADFFLALTICNSVMVSTTTEPRKRVTTPPANKALGTSLEKIQQLFQRLKLLSLSQSFSSTAPSDTDLGESLGPNLPTIDSDEKDDTSVCSG-DCSTDGGYRSSTWEQGDILGSESGTSLEEGLEAPTLSQDEPELCYEAESPDEAALVHAARAYSFTLVSRTPEQVTVRLPQG-ICLTFDLLFTLGFDSVRKRMSVVVRHPLTDEIIVYTKGADSVIMDLLEDPACESNIDVEKKLKRIRARTQKHLDLYARDGLRTLCIAKKVVDEEDFQRWASFRREAEASLDNREELLMETAQHLENHLTLLGATGIEDRLQEGVPDTIAALREAGIQLWVLTGDKQETAVNIAYSCKLLDQTDTVYSINTENQETCESILNCTLEDIKRFHEPQQPARKLCGHRIPPKMPSVNSGAMAPEIGLVIDGKTLNAIFQG--KLENKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLSVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAIARFSHLKKLLLVHGHWCYSRLARMVVYYFYKNVCYVNLLFWYQFFCGFSGSTMIDYWQMIFFNLFFTSLPPIIFGVLDKDVSAETLLALPELYKSGQNSECYNLPTFWVSMADAFYQSLICFFIPYLTYRGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTVLHGLVLLGSFLMYFVVSLIYNATCVTCNSPTNPYWVMERQLSDPTFYLICLLTPVVALLPRYFLLSLQGTYGKSLISKAQKIDKLPIDKRNLEIQNWRSKQRPAPASASASASAPATGTVHTRPPCHPVPPEAQQNFGASTSKSSGPPRQKHVEDRVLQDPRCSREHSRDDTCTVDTLAKLSSGECLLDPNRTVAPTAYSRGQKDVSRHSSKGSHRRSQSSLTI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A4W5-1", "uniprot_id": "D4A4W5_RAT", "id": "D4A4W5-1", "name": "Phospholipid-transporting ATPase", "aln": "---------------------------------------------------------------------------------------------------------------------MTFSLDFSWLRWKWR--------------SQNGFSQSPSETTPLLSP----ETGRQSYNPT-----------------------------------------------EQRVVYPNNSMCHQD--WKKVSRRYPGNSICTTKYTLLTFLPQNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAIVLLVIMVKDGTEDFKRYCFDREMNSASIQIYERKEQSYMQKRWQDVRVGDFVQMRCNEIVPADILLLFSSDPSGVCHLETANLDGETNLKQRRVVKGFSQQEVQFQPEHFHSTIVCEKPNNHLSKFKGYMEHPDETRTGFGSESLLLRGCTIRNTEVAAGIVIYAGHETKAMLNNSGPRYKRSKIERRINTDIFFCIGLLFLMCLIGAVGHSLWNGTFKEHPPFDVPDADGNFLSPALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFLLHNDLDLYDEETDLSIQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTIVGNEYCHQENAKRLEMPKELDSDGEEWTQYQCLSFPPRWTQGPATIRSQGGAQPLRRCHSARVPIQSHSRQRSVGRWETSQPPVAFSSSIEKDVTPDKNLLSKVRDAALWLETL-DTRPAKPSHSTTASIADFFLALTICNSVMVSTTTEPRKRVTTPPANKALGTSLEKIQHLFQRLKLLSLSQSFSSTAPSDTDLGESLGPNVPTIDADEKDDASVCSG-DCSTDGGYRSSTWEQGDNLGSESGTSLEEGLEAPALSLDGPELCYEAESPDEAALVHAARAYSFTLVSRTPEQVTVRLPQG-ICLTFDLLFTLGFDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACGNDIDVEKKLKRIRARTQKHLDLYARDGLRTLCIAKKVVNEEDFQRWASFRREAEASLDNREELLMETAQHLENRLTLLGATGIEDRLQEGVPDTIAALREAGIQLWVLTGDKQETAVNVAHSCKLLDQADTVYSINTENQETCESILNCALEDVKRFHEPQQPARKLCGYCIPSKKPSVNLGAMAPEIGLVIDGKTLNAIFQG--KLENKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLSVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAIARFSHLKKLLLVHGHWCYSRLARMVVYYFYKNVCYVNLLFWYQFFCGFSGSTMIDYWQMIFFNLFFTSLPPIVFGILDKDVSAETLLALPELYKSGQNSECYNLPTFWVSMADAFYQSLICFFIPYLTYRGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTVLHGLVLLGSFLMYFVVSLIYNATCVTCNSPTNPYWLMERQLSDPMFYLTCLLTPVVALLPRYFLLSLQGTYGKSLISKAQKIDKLPIDKRNLEIQNWRSKQRPTP--ASASAAAPATGTVHTQPPCCPVPPEAQQDFGASTSKSSSPPRQKQVEDWVLQGPRCSREHSKDDTCSRDTLAKLSSGECLLDPNRTVAPTAYSRGQKDASRHSSKGSHRRSQSSLTI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O94823-1", "uniprot_id": "AT10B_HUMAN", "id": "O94823-1", "name": "Phospholipid-transporting ATPase VB", "aln": "---------------------------------------------------------------------------------------------------------------------MALSVDSSWHRWQWR--------------VRDGFPHCPSETTPLLSP----EKGRQSYNLT-----------------------------------------------QQRVVFPNNSIFHQD--WEEVSRRYPGNRTCTTKYTLFTFLPRNLFEQFHRWANLYFLFLVILNWMPSMEVFHREITMLPLAIVLFVIMIKDGMEDFKRHRFDKAINCSNIRIYERKEQTYVQKCWKDVRVGDFIQMKCNEIVPADILLLFSSDPNGICHLETASLDGETNLKQRCVVKGFSQQEVQFEPELFHNTIVCEKPNNHLNKFKGYMEHPDQTRTGFGCESLLLRGCTIRNTEMAVGIVIYAGHETKAMLNNSGPRYKRSKIERRMNIDIFFCIGILILMCLIGAVGHSIWNGTFEEHPPFDVPDANGSFLPSALGGFYMFLTMIILLQVLIPISLYVSIELVKLGQVFFLSNDLDLYDEETDLSIQCRALNIAEDLGQIQYIFSDKTGTLTENKMVFRRCTIMGSEYSHQENAKRLETPKELDSDGEEWTQYQCLSFSARWAQDPATMRSQKGAQPLRRSQSARVPIQGHYRQRSMGHRESSQPPVAFSSSIEKDVTPDKNLLTKVRDAALWLETLSDSRPAKASLSTTSSIADFFLALTICNSVMVSTTTEPRQRVTIKPSSKALGTSLEKIQQLFQKLKLLSLSQSFSSTAPSDTDLGESLGANVATTDSDERDDASVCSGGDSTDDGGYRSSMWDQGDILESGSGTSLEEALEAPATDLARPEFCYEAESPDEAALVHAAHAYSFTLVSRTPEQVTVRLPQG-TCLTFSLLCTLGFDSVRKRMSVVVRHPLTGEIVVYTKGADSVIMDLLEDPACVPDINMEKKLRKIRARTQKHLDLYARDGLRTLCIAKKVVSEEDFRRWASFRREAEASLDNRDELLMETAQHLENQLTLLGATGIEDRLQEGVPDTIATLREAGIQLWVLTGDKQETAVNIAHSCRLLNQTDTVYTINTENQETCESILNCALEELKQFRELQKPDRKLFGFRLPSKTPSITSEAVVPEAGLVIDGKTLNAIFQG--KLEKKFLELTQYCRSVLCCRSTPLQKSMIVKLVRDKLRVMTLSIGDGANDVSMIQAADIGIGISGQEGMQAVMSSDFAITRFKHLKKLLLVHGHWCYSRLARMVVYYLYKNVCYVNLLFWYQFFCGFSSSTMIDYWQMIFFNLFFTSLPPLVFGVLDKDISAETLLALPELYKSGQNSECYNLSTFWISMVDAFYQSLICFFIPYLAYKGSDIDVFTFGTPINTISLTTILLHQAMEMKTWTIFHGVVLLGSFLMYFLVSLLYNATCVICNSPTNPYWVMEGQLSNPTFYLVCFLTPVVALLPRYFFLSLQGTCGKSLISKAQKIDKLPPDKRNLEIQSWRSRQRPAP--------VPEV----ARPTHHPVSSITGQDFSASTPKSSNPPKRKHVEESVLHEQRCGTECMRDDSCSGDSSAQLSSGEHLLGPNRIMA---YSRGQTDMCRCSKRSSHRRSQSSLTI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FFI1-1", "uniprot_id": "E7FFI1_DANRE", "id": "E7FFI1-1", "name": "Phospholipid-transporting ATPase", "aln": "---------------------------------------------------------------------------------------------------------------------MTWTSPLTLFQRGWT--------------RHRDQDRPIRKVVSNLPF----EDLRK---------------------------------------------------------------------REQPNRQYEGNAIKTNKYRLWSFLPMNLFEQFHRLANIYFVGLAILNFIPVVNAFQPEVALIPICIILALTAVKDGWEDFRRYQTDQQLNNMPCFIFRRRLMCFVERRWKDVRVGDFVKVLSNEIIPADILLLHTSDPNGVCHMETANLDGETNLKQRKVVPGFSTLGEPFQPQTFDSTVVCENPNNNLNLFKGFIERPDKRRSGFGIDSLLLRGCTVRNTDDAAGIVVYAGHETKSMLNNNGPRYKRSKIERKMNTDVLFCVLLLFFMCLIGALGHAIWLETFSTMPSYIVPDSNGNYISSALAGFYMFFTMIILLQVMIPVSLYVSIELVKMGQIFFITQDAELYDQELDSRVQCRALNITEDLGQIQYVFSDKTGTLTENKMVFKRCTIMGTEYCHEENAARLAVINGGGNEEEEVTIYQKTKLPPLFPLEELQDDHTG------HKNHANTQVAAASRRRSK-VAAGAQSDMAFSSPLETVVVPDRKLMLEVDHQMASIQTG--------------PYLDFFLALAICNTVVVSTLTAQRQRVKGRRNSSYSGSSSHNMGQWFK---ISSLQKFFSSMR---FKRNRETMADPFAIDEDEPDTFHISSVSDSRPGQKVISS-----------------EGKDKRSLSRSE-EVCYEAHSPDEAALIHAAKAYGFTMVERTPRYVTVKLPNE-TLLKFEVLDVLTFDSTRRRMSIIVRHPHTNEIIMYTKGADSAVMEKLGN-----VFSVESAAKRIAVRTQKDLDMYARDGLRTLCFAKKVISEQEFKAWFTSRQEALSAIDEKEERLMETANDIENNLTLLGATGIEDRLQENVPETIQALRRAGMQVWVLTGDKPETAVNIAYSCKLLDHEDLVFTFTTNKKSVCKMRLEDTLSEVRRTWGGLGLDPQFRGYNSTFTGP-----LMEPSIGLVIDGPTLNMALSE--DLVEQFVELCKHCRAVLCCRVTPLQKSSVVKVIRQKLRVMTLAVGDGANDVNMIQAADVGIGVSGQEGMQAVMASDFAITRFKHLQRLLLVHGHWCYSRLANMVIYFFYKNVAYVNLLFWYQFFCGFSGTAMIDYWLMIFFNLFFTSAPPIMFGIMDKEVSDSTLLSLPELYRRGQHSEGYRRSTFWIAILDAFYQSLVCFFIPYWTYNDSDIGIFSFGTPMNTVSLFTIILHLAIEIKSWTVVHWVIMVGSVLVYFILTLAYSAICISCNPPSDPYWIMHKQMADPMFYLVCVLTTVVALLPRYTLRVLKGTLAPSLHLRARQLERLPSSCREQQIREWRGFR---------------------------------------------------------------------DTCIS---ASLSSTACPSA-----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KTG6-1", "uniprot_id": "Q7KTG6_DROME", "id": "Q7KTG6-1", "name": "Phospholipid-transporting ATPase", "aln": "MPSANTEDLRRKFLVVQQQRSAPPNLTGDTLSSGIPNASASSATTSLMMTTSTGLGGVAMGAGEPERTYVFPGGNPVVGSAPGGGGQGIPGVAMAAPSRGHARSISHGGGAIVGANGRPIKSAMKGHQRAFSQGQITDSPPGSAAPAGRGHSRVGSKTDFILPPGHKEEPAREPSAPTSATGGRGHSRQASRSESIYTLRRTEAPPWWKRLTLCNYNTGDKFEERSYRTVVPNHTVPPKTPKRDHPNGQFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIFVPSKFVSRVEADAPTTKLYRFHGALIHPTGERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMWLSSFTHFP---VPYLPPNKLTANMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPPSELEKIYSKPGAPAPPLIPNDNLNSDMAQLTQGTYLTPHAQRIQEFLVVLAICNTVIVGAAPHRDMMNASGIIEVQQIGNSPANLKHGKQRQKLLASSTSTTTTTTIINGPTTQPQVVSIPADRYIRLAESRSVTPSPPPNLLFALPAQSHQPTLSPISSSAESSPN-----SESESPSPPMK-NKSLSNSISPTGRAKAVINSKITSIATFLNAKTQGKRMKLP----------------SSKTGTIYRTADGRPLYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVP------CSHNSPEGILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDME-----NDKTTSTLGYGQSLRKK---------QRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSFYLFAIVYDSVCMNCFGVRSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCPDDSTKVILQSKRERSRGEALLVTWSRST---------------------------------------------------------------------SASSIYRITDYGSKNQIITTIT--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : : . : :. *. * *: .. :: ** *.** * :*:* **:***** **:**: :.:**::* :..* *::::*: :* : :** ** :* *: :* :: . : *:::****:::: ** :******* :***.*:*:::*..********:* ** **. * *. * . : .: *..:* *:* : :* * :. :.**** . ::**: ***:*******:****.*******::*:::* *:::*: :*:::*::**:* :* :* * ** . :. : .:::* * *::***:**:****:*** *: *:* : :: :*:* * : :***:**:*:*****::*:***********:*:**.: *.:* * . . : . : . . . : : . : . : .:: : * * :: *: ..:* *. . : . .. . : * .: *. . ... . : : . :.: :. . .. . ***.**** **::** :*. ::.*:*. : * :* :.:* .* *** *: **::**: : **::******* :* * . :. : :**: ** ***:*** * :**:.:.. :: * : ::* ::::::. * :: .:*..**************:.**:** :* **:.:******* ***:*:*:*.:*: : : :.:..:...: :: * ::. . *. . . .**:** **. :. .* *:.* : * :***** *****: :**:::::* : **::*******.*** **:*:*:**********::**::.** :*::***.**:***.**:.*::*::***..:* *:****::****. .*:* ::::**:*** **: :*: ** :: . ** * **: *: . *. **: : **:****: **:. :* **:.:: ***.:.: .* : ::* *:*:::**:.* : :: *. :::.:: *.: *: * ..**:: ::.. .:* .*:.***:*** : :: : . :. .: . : : * .:. :. .* ", "identical_positions": 404, "similar_positions": 412, "identity": "24.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-797", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTF0-1", "uniprot_id": "D3ZTF0_RAT", "id": "D3ZTF0-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTRTDPPDLLVSTVYQDIKVVDPGLTSKRQPCERSVARPAASTPFN------------------KRHCRSFD-----------------------------------------FLEALDEPTMETHPEP-------------------PPPEPAPPRARPRDGEPR--RRTRSKSAPR----------------------------------------VPQSLTTAPASP-PVLQRRGREAQRAVR-----VEGSPCREPSYPALR------------------------------------------------------ALANELHPIKLQPQRGGPGRIAP-------------------------------------------------------------------------------LCATPGRCAPPESSAGPVPHVRCR--------------------------------------------------LDIKP---------------------------------------DEAVLQHAARSSRSGAPRETSSWAR-TVPQFHGLTVPGPRHVALSRTP--------TPSDLYCTDPRPLYCDGP-LPG------------------------------------------PRDYLEHRTQPFTTPPG------PTQFFYTEEPEGYAGSFTASP-----------GLPFDGYCS---------------------------------------------------------------------------------------RPYLSEEPPRPSPRR---GGSYYAGEVRTFPIQEPP---------------------SRSYYG----------------ETTRAYGLPFVPR---YVPE----EPRVHPGARAFYTEDFGRYRERDALARTYPHPRSSPT---------------------------------------------------------------------------------------------WADWGPRPYRTLQVMPPPAPGPL-----------------------------------------------------------------------------------------------------------------------------LASWHGGTGTSPPRLVTDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVRDTRGSSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKG--RTGECLGRNWYVTPEIT--------------------------------ITDNDLR--SAERPTAK--GWELPGGRPRQPVPVVPEGPASSR---------------QRSLEQLDELITDLVIDSR-SPAQAPEPTAEGLGRQLRR--------------LLDSRPA---------------------------------------GPGGATALAPSRSPPASAGSTEEPTG----------------------------------------------------SGE----AAEASPEPSADED-----------------------------------------------------DLMTCSNARCRRTETMFNACLYFKSCHSCYTYYCSRLCRREDWDAHKARCVYGRVGSVCRHVLQFCRDSSPVHRAFSRIARVGFLSRGRGVLFLGFPSPGSADNFLRFGLEGLLLSPTYLSLRELATHAAPLGSYARELAAAGRLYEPAECFLLSVSVAVGPGAAPPGAAAR--PAPRSPGPTVRKFAKVALAAGSPTRPPPARGGEPDMETLILTPPPGTAGLDEEGEAGRRAREVAFIHIQRELRLRGVFLRHEFPRVYEQLCEFVEANR-RFTPTTIYPTDRRTGRPFMCMIMAASEPRALDWVASAN---------------------LLDDIM--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AJA9-1", "uniprot_id": "AJM1_MOUSE", "id": "A2AJA9-1", "name": "Apical junction component 1 homolog", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTRTDPPDLLVSTVYQDIKVVDPGLTSKRQPCERSVARPAAPTPFN------------------KRHCRSFD-----------------------------------------FLEALDEPTMETHPEP-------------------PPPEPAPPRARPRDSEPR--RRTRSKSAPR----------------------------------------ASQGLATAPASP-PVLQRRGREAQRAVR-----VEGSPRREPSYPALR------------------------------------------------------ALANELHPIKLQPQRGGPGRIAP-------------------------------------------------------------------------------LCATPGRCAPPEPPSGPVPHVRCR--------------------------------------------------LDIKP---------------------------------------DEAVLQHAARSSRSCAPRETTSWAR-TAPQFHGLTVPGPRHVALSRTP--------TPSDLYCTDPRTLYCDGP-LPG------------------------------------------PRDYLEHRSQPFTTPPG------PTQFFYTEEPEGYAGSFTTSP-----------GLPFDGYCS---------------------------------------------------------------------------------------RPYLSEEPPRPSPRR---GGSYYAGEVRTFPIQEPP---------------------SRSYYG----------------ETTRAYGMPFVPR---YVPE----EPRAHPGARTFYTEDFGRYRERDVLARTYPHPRSSPP---------------------------------------------------------------------------------------------WADWGPRPYRTLQVMPPPAPGPL-----------------------------------------------------------------------------------------------------------------------------LASWHGGTGTSPPRLATDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVRDTRGSSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKG--RAGESLGRNWYVTPEIT--------------------------------ITDNDLR--SVDRPTAK--GWELPGGRPRQPVSTVPEGPASSR---------------QRSLEQLDELITDLVIDSR-SPAQAPEPAAEGLGRQLRR--------------LLDSRAA---------------------------------------GPGGATLLAPSRSPPASAGSTEEPTG----------------------------------------------------SGE----AADASPEPSADED-----------------------------------------------------DLMTCSNARCRRTETMFNACLYFKSCHSCYTYYCSRLCRREDWDAHKARCVYGRVGSVCRHVLQFCRDSSPVHRAFSRIARVGFLSRGRGVLFLGFPSPGSADNFLRFGLEGLLLSPTYLSLRELATHAAPLGSYARELAAAGRLYEPAECFLLSVSVAVGPSAAPPGAAAR--PAPRTPGPTVRKFAKVALAAGSPTRPPPARGGEPDMETLILTPPPGTAGLDEEGEAGRRAREVAFIHIQRELRMRGVFLRHEFPRVYEQLCEFVEANR-RFTPTTIYPTDRRTGRPFMCMIMAASEPRALDWVASAN---------------------LLDDIM--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "C9J069-1", "uniprot_id": "AJM1_HUMAN", "id": "C9J069-1", "name": "Apical junction component 1 homolog", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTRTDPPDLLVSTVYQDIKVATPGPASKCSPCERSVARPAEPAPFN------------------KRHCRSFD-----------------------------------------FLEALDGPAMETLPEP-------------------PPPESAVPRARTREAEPR--RRARSKSAPR----------------------------------------APPGLTPAPASP-PVLPRRGREAQRAAR-----AEASPRREPAYPALR------------------------------------------------------ALANELHPIKLQPQRGGPGRVAP-------------------------------------------------------------------------------LCAAAGRCAPPEPPAGPAPHVRCR--------------------------------------------------LDIKP---------------------------------------DDAVLQHATRGSRSCGPTEAAHWAR-PAPQFHGLTVPGPRHMALSRTP--------TPSDSYCADPRAFYCDGP-LPG------------------------------------------PRDYAERRSLPFTTPPG------PTQFFYTEEPQGFRGSFAASP-----------GPTFDAYYP---------------------------------------------------------------------------------------RPYPSEELSGPSPRR---MGGYYAGEVRTFPIQEPP---------------------SRSYYG----------------EAPRAYGLPYGPR---YVPE----EPRAHSTARPFYTEDFGRYRERDVLARTYPHPRSSPA---------------------------------------------------------------------------------------------WADWGPRPYRTLQVVPPSDPDPL-----------------------------------------------------------------------------------------------------------------------------LASWHGGTGTSPPRLATDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVREPRGVSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKG--RAGEGLGRNWYVTPEIT--------------------------------ITDNDLR--ATERPSAR--AWELPGGRTRPPPHAAPDGPTSGR---------------QRSLEQLDELITDLVIDSRPTAGQASEPAADCLGPQLRR--------------LLDSRPA---------------------------------------GSG-APALAPPRSPPASAGSAEEPAA----------------------------------------------------PGE----AADASPEPSADED-----------------------------------------------------DLMTCSNARCRRTETMFNACLYFKSCHSCYTYYCSRLCRREDWDAHKARCVYGRVGSVCRHVLQFCRDSGPVHRAFSRIARVGFLSRGRGVLFLGFPSPGSADNFLRFGLEGLLLSPTYLSLRELATHAAPLGSYARELAAAGRLYEPAECFLLSVSVAVGPGTAPPGTPALPAPAPRSHGPTVRKFAKVALAAGSPARPPPARSREPDMETLILTPPPGTAGLDQDGEAGRRAREVAFIHIQRELRLRGVFLRHEFPRVYEQLCEFVEANR-RFTPTTIYPTDRRTGRPFMCMIMAASEPRALDWVASAN---------------------LLDDIM--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YZ78-1", "uniprot_id": "A0A8M6YZ78_DANRE", "id": "A0A8M6YZ78-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTRTDPPDILVSTVYQDVKVSSLSTHSKACHPSKQCDSPSVSKLENTRKKS----------KNKKRHCRSFDTESMDKLRYHTIAMEYPYRRAERYAANPEVAWNALGRQQGHGLHRFSSPDIFSYRLT-------------------SQPTAAEMPAEIAVTEQK--RRTRSRSASR----------------------------------------VQTSLTPVSFDASPPVARRGREAQRAHRNSQPRPEVSPRRESSYGATR------------------------------------------------------AHVNEVHPVKLQPQRSDTSRYSP-------------------------------------------------------------------------------VYVPEGYDEGRPEKPATSPHVRCR--------------------------------------------------VDIKP---------------------------------------DESAMQQGGR--KAATPQVDIPWQKYPGSGSRSLTVP--RHFSTSRTP--------TPTESYMGEYRQAYQYSQSMPNSYMQPMEIPLQKVV------------------------SPREPREHYGRERRAHSSPNV------PTKFFYAEDLGKYGSSAPSRT-----------YYQDDRYSIPSQPYSPKVQYV--------------------------------------------------------------QDPRTHIVHTVPTRPYYTEVDPYHYSGQHVYAKSYAASEPGAYIIQTPP---------------------GRTLYG----------------DDPRTYQIQTAPPRIFYMADPYTPQMEHHIPAKAYYTE--GRRHARVVQPQSEDWYGSDVSG--------------------------------------------------------------------------------------------YSSHYPSSYVSQITPTRARQEPK-----------------------------------------------------------------------------------------------------------------------------LTTWYANPCMEPAKTVTDPRSYSRSWDNILDTHVEREQPVPRGKSDENLLCQGAQTS-----SERPKPVVVNLSSSPRRYAALSLSENSLIDKSPTEAMSSSSKLWFVTPEIT--------------------------------ITDNDIRQGNLGKPEARSASWDVLDSKSAQN-QEAPQRDAKSRSGESTKEKTHSSTSLQQSLEQLDELLADLVIDYKPPARRTSEDLLDQLKKLIDEEEA-------VSSARKDSTPG---------------------------------------SESGMPLDKQPTSIKIDPDTLRDTDG----------------------------------------------------SCDGLRSTEECSPDQSPDED-----------------------------------------------------DTMMCSNNKCRRTETLFNACLYFKSCHSCYTYYCSRNCRREDWDIHKESCLYGRIGSVCRHIIKHCRETTEVHKAFSRIAKVGYLSRGRGVLFLGFPNPGSSTNFLQFGLESLLMSPTYLSLRELESFKDNLGEYCKELQEAGKEYDPNECFLLNVSIAVG-DQVPDG------PSPRVQAPTVRKFAKVALASYSPEKK--VHRKESDMETLILTPPPGMADIDKEGEEGRKAREICFINIQRELRIRGVFLRHEYPNVYQKLCEFVENNR-RFTPTTIYPIDKRTGKQFMCMIMAASEPRTLDWVANPH---------------------LLDDII--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PDE6-1", "uniprot_id": "M9PDE6_DROME", "id": "M9PDE6-1", "name": "Apical junction molecule ajm1 alpha/beta domain-containing protein", "aln": "MVTICSLSAALSCNIAYRFPIYEMEHLDLAGYLGHTPQSWNTLGTFQDQDAVYLSSSRQMLEPILEETSEDEERARSSLIVSLDRRSTLWSSTESETGSVLRIETIKADIDAVSERDFVCPPKRPRRSHDLNSGQISEDCVQLRRPMPYDPEYHNSFERFLALEACARDSFGSQGQRSSIGSRRGGTFEDFYSDRDSSHSLSRSSSLVQFESLERQLTLQEQHQSMNSLGNSSPSLTCESGASTRARTRDSSPESRKGSAPTLSLLKRYESSDCSHLHQTYYELNNLNFEYKQQQELLSRSLREAELKSDLESSSSSSSSSDSSGHSLLSSCLVPGDAVATERGKQDGTNSRRIPPNSAENLSEDSGYCEPRTLKREKSKSIPKNFEKLCEEEEELLLLEEGAPHSRDFKDEHDLCQTEIEQTADTAALACSPSSINSSPERASSESESASPLPSPTGSASTSSAASFTWLHNSLPDIREPRGPLSVEINNSKPKTNGSVLATTRQNSGSTRSSSSADSCDGISLLGPTHSLNELQVLERRRRPRHIRPSQRNCHSNSSSEELEELDNLFVACHTPPRIRRSCSWNERARKVVGVASAGYLNASYQNLTLLNYTDNWLPAEILQKNHKRSPAEEMSKQSSNTCGNYEHMICKGNFLLDEISKVYDKNVSILTDKPVLDTKLPAPVECDLNEPIECSKVQHVQLNIKPPPRQKRLTQQPPAAMTFNGLVKTFDQDPTNLRTSYTQSLEQCHLDEQETAKPASYPPSAISQRFLPKRRFQSQTSAAKQRSLVSSTPNLAASDDGQPESEYDIYVSSAHASMHQLPQTTTLPKPLGILLPAGSRHSFGKEVSFCPVVSKYCWQEQSSEEPTEDQFHSSEGEQGPPSDDELMDPTLVHNTRENENIAALFEPEPEQAHRLREPAIAQKFTGFHTNALLSASTHAEKNLSCEESANVKNKANLATPDCRDQRTEAKTTLEPEPALSSTVSLKPCAVANSSCREETPSDAINEPASATARPLSLPILSEPPTNRAHRILYSSQQLRRYEPKASPINKMPPANELSPQAAAVARTDEKHPTSRSLFSRFTHGLRFSLRRKKKQQQQEPSQVKESPKELRQSPEESQPVDFVHIPLKPPRSSQCGRLDDTIVSETSSGHVHSWQQQEQLGKTSTLQKVTGKPPLPKMPPRSGILTHAPQETTGETVNCHRTEALPSVEREHCNQLTGQLVAKVQAQRMRDTGLSSQIVVAEETHTVNRLAGHGDATRPTVVTAVPVSVAPVAEVDKMGLIETNLDTHETVISGKTRSLMDITCNPLSMPHKRYIVKRLNVNSVAYDVDELDAEVKPSPGGMASVRRPHKSMEFLLDKENQKNILPPENELQKSHDHNPGALSEHQLRVQASLQRLNIPDWFRHYNKGPEKAADGENACTSATGGGYRPGNFTRKRAQESGRWQGLNSKTTSLSSLGSQRSDRSPLLMSPSAHSHHGGQSSYSCGSTTIHGPAPVQIGMGATRWSTSHLNSTQMSPGASQRGSFTRGAPINSSFISVASGSGLLRNSYRQPYLGWRSTEKLSQRTPHERLANSLLTQRTAPPSTRAGNETRTLHSVSTEIQSSIKEVTSAIVHFVNDQQQSQHPRSRSTSPNSRCWLESSFVGTRTLDSPQTPVIDNSPPELARKQQQLHPHQVHLDVGLSPVVSAGQLPHRMNGINRIGNGGVPTRNIAPERSLSSASLEDVLASLLGLPTTLLSGQNSNSYSSYTPNAATTACAASRQQLEVQSAAELQRLRRRSEGDAPTQEKHYSKEQSHKSNSHSVEAVDSAQPNNPKESRRASLGDPALAATRSDIGSGQLQLIEGPTTGFGSGQHVRCRNTKCDQSTSPSDAKKLYKSCHNCSHLYCSRECRRAHWEKHRKACLHSRASNICRQVLATCKDDIDSQRHLSLLARKGSLSQGRGVVRVLFRSAEAAEGFIKNGFQ-CMGEASYVRWPDLMPAEMGLELYS-ELLKLSTEYKPETKMLIYVAICVVSEAPGMG-----QAPVRWERQLVSRCAKLKLCKTVLAELEQHQAALLQPVSVVAVPERTEILILTFNPGQHSNRELILSNILDILSRRGVMLSKHYPEVFERLQTYSEGQSDKFNPVTLHPRDTQTGQNFVCIIMAVHTDNELTKLPSAADGGNRVTTIDVGSTSALVQLELGDDQICKTKSRES", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: :. : :: *. .: . * . : . . . .* :. . . . : : . . . * : :* :*:* .: .*: . . . * . *:: * . *. .:: : . .:.:: ::: :* . : * . . *: *: ::*** ::. ::. : * . :. * . :: * ** * . * : :* * : : * ** .. :.: . . . : * :* . * : *: * .*: :. : .. : * .: * :. :. ** . : * :. . : . * :. *. * : . . . : : .. . .. .. :.* : . . *:::. *: .:: . * * * :. . . : *..:. : *. * :. . : .. * * *:::: . :..:* * : . .. : *. . . . . . . .. : .: . : . * : * ..: : : * * :* :: : :* :****.* **** *** .*: *: *::.* ..:**::: *:: :: :* :*: * **:****: : * .. :: .*:: *:: : ..:*: :* . * *. ** . *.* :*: *::.* * .. * * : **: *. . : : ::: .* : . : **: : :* * ***:* :.:*.*:::* : * : :*.*.*::* * :**: *:*:***. . * :... * ** : ", "identical_positions": 143, "similar_positions": 297, "identity": "6.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-800", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PT59-1", "uniprot_id": "E9PT59_RAT", "id": "E9PT59-1", "name": "", "aln": "MEAEEPEHGACTPVPDIEELGAIPEGIMRSSQIPALDPEAQEGQDPSYKWTDGHRSLMDQSKVLRDVSDHTPNSVAIFFKKDSSAMATSQEILLAEARDTADQQEAVTQSLQDRLSTTVAAPELLGCAVQEEWLDIP---SKLDS-RVEAELQPELMSLTLAVSKEKEEEESSPDTSTP-GFWPPSKIHPGETDQTEGSGMELLRQGKQLQLEATQENRGQQGLLQPQEAQGLEEQEGQEVEIQEEGTLREDICFGGLLGEQKEVEEDFNDN-KEEQKQEQIQSYMLLGGQWESEGLSGELEGLNYNERSQEERERRVCGQRDSKE-EGQDQELREVEERRVGTQCAENQMLEEISENVRRRQEDHDQAGQAMHVGDQKEVVDSGDREQGTWDSGGQAAEERSRTGEDNKPCLPMTSIAPGVLSPGTLFPAIPSSVDDMSQIQREPVPEELTTQAPTPAPEPTEWSHQHISPPASFATEEALDN-RTHDSQQEEFKLRKGTISNQGTENVSASISVAPSGTPDLPPFTPPNVFPTTATFSLVSSSVILPEKETPAASISADISPHYGPCETPPLPAKSTRDPCAT----SDTANPHSPLTSYTGVTQHLRSNSFPGSHRTEQTPDSMGMSLSFSHLELPQRPP--KTAIYGSLIPRRNRRS-RDGVVFSESSAALFALKQDSEEFTSNPESSSNPHGSQPWGSPQNSAFAIGSPVNVSSPPTVSMDM--IHEALPPPPPEKRHSYSHIVERDGLFHEVAATLKRHSHPPPLTLSSGLHRSPKGSFSLVPDSVVARQHRPLPSTPEGSHHTQTSIPSRLRYNKPLPPTPDMPEPCHSSISSSNISRIYRPLPPVPITDPSSEPPPLPPKSRERSRSVQVGVMHSMGQANPRTTGQDWTVST-LSVGRTSWPPATGRSTESLPPTSRCNSEVSPGLAFSNMTNLLSPSSPTTPWSPELQIPTSKDESGLTEESAPPVRGSFRRPALQEEFNNTRRSALGSRKKSEKPIHYQLEKASSWPHRRDTARTS-ESSSEQVVLGQAPNKQKGWNRQGLRRPSILPESSSDLRNPAAGRLPGSSDSVVFREKKPKEGMGGFSRRCSKLINSSQLLYQEYSDVVLNKEIQSQQRLDSLAEPPGISSPRYRRKALVSSDSYLQRLSMASSGSLWQEIPVVRNSTVLLSMTHEDQKLQEAKFELIVSEASYLRSLNIAVDHFQHSTQLRATLSNQDHQWLFSRLQDVRDVSTTFLSDLEENFENNIFSFQVCDVVLDHAPDFHRVYLPYVTNQTYQERTFQSLMNSNSSFREVLEKLESDPVCQRLSLKSFLILPFQRITRLKLLLQNILKRTQPGSSEEAEATKAHHALEKLIRDCNSNVQRMRRTEELIYLSQKIEFECKIFPLISQSRWLVKSGELTALEFSVSPGLKRKLTTRPVHLHLFNDCLLLSRPREGSRFLVFDHAPFSSIRGEKCEMKLHGAHKNLFRLFLLHNAQGTQAEFLFRTETQSEKLRWISALAMPREELDLLECYDSPQVQCLRAYKPRENDELALEKADVVMVTQQSSDGWLEGVRLSDGEQGWFPLQQVEFISNPEVRVQNLKEAHRVKTAKLQLVEQQV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q7D5-1", "uniprot_id": "ARHG5_MOUSE", "id": "E9Q7D5-1", "name": "Rho guanine nucleotide exchange factor 5", "aln": "MEAEEPEYGVSTEVPDIEELKTIPEGIMRSSQIPALDPEAQEDRDPSYKWTDGHRPVMNQSKVLRDMGDHTPNSMAIFFKKESSDMETSQEILLAEACNTPDQQEAVIQSLKDRLSRTIAAPELLACAVQEEWLDIP---SKLDN-RVGAELQSELMSLTLAVSKEKEEEETSPDTSIPRGSWPPCKTHPGETEQTQGSGSELLRQGKQLQLEATQENQGQEGFLQSQEAQGLEEQEGQEVEIQEEGTLNEGICFGGLLGEQEEVEEGFNGN-EEEQKQGQIQSYMLLGGQWENEGLSGELEGLNYSERGQENRERRVWVLRDSEE-EGQDQESREVEERRVATQYTENQRLVEKSEIVKRKQRDHDQTGKVMPVRDQKEVVDSGDRVQGNGDSGGQTAVEGSRPGEDSKPSLPVASVDPEVLSPGTLFPGISSSVADIPQIQKEPVCEELSPQAP--ALEPTEWSHQPISPPASFAPEESLDN-RTHNSQQEEFRLRKG------IEVVSASTSVAPSGTRDSPPFSPPNVFSSTATLSPVSSSVILP-EETPTASASADTPHHCGPCETPPLPAKSSRYPCAT----SDTANPHSPLSSYTGVTQHLRSNSFPGSHRTEQTPDSLGMSLSFSHLELPQRPP--KPAIYGSLTPRRNRRS-RDGIVFSDSSTALFALKQDSEEFTSNPERPSSPHGSPTWGSPQNSAFAIGSPANVSSPPTVSMDMT-IREALLPIPPEKRHSYSHIVERDGLLHEVASTLKRHSHPPPLTLSSGLHRSSKGSFSLVPDSTVARQHRPLPSTPESPNHTQTSIPSRLRYNKPLPPTPDMPEFYHPSISSSYISRMYRPLPPVPIIDPSSEPPPLPPKSRGRSKSIQGGVIHSGGQAKPRPNNQDWTAST-LSVGRTSWPPATGRSTESLPLTSRCNNEVSPGLAFSNMTNLLSPSSPTTPWIPDLQRPTTKDESGLTEESEPPVRGSFRRSAPQEEFNNTRRSALGSRKNSEKPLHHQLEKASSWPHRRDPARTS-ESSSEQVVLGQVPNKQKGWNRQGLRRPSILPESSSDLRNPAAGRLPGSSDSVVFREKKPKEGMGGFSRRCSKLISS-QLLYQEYSDVVLNKEIQSQQRLDSLAEPHGLSSPRHRRKALVSSDSYLQRLSMASSGSLWQEIPVVRNSTVLLSMTHEDQKLQEAKFELIVSEASYLRSLNIAVDHFQHSAQLRGTLSNQDHQWLFSRLQDVRDVSTTFLSDLEENFENNIFSFQVCDVVLNHAADFHRVYLPYVTNQTYQERTFQSLMNSNSSFREVLEKLESDPICQRLSLKSFLILPFQRITRLKLLLQNILKRTQPGSSEEAEATKAHHALEKLIRDCNSNVQRMRRTEELIYLSQKIEFECKIFPLISQSRWLVKSGELTALEFSVSPGLRRKLTTRPVHLHLFNDCLLLSRPREGSRFLVFDHAPFSSIRGEKCEMKLHGPHKNLFRLFLLHNAQGTQVEFLFRTETQSEKLRWISALAMPREELDLLECYDSPQVQCLRAYKPRENDELALEKADVVMVTQQSSDGWLEGVRLSDGEQGWFPVQQVEFISNPEVRAQNLKEAHRVKTAKLQLVEQQV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12774-1", "uniprot_id": "ARHG5_HUMAN", "id": "Q12774-1", "name": "Rho guanine nucleotide exchange factor 5", "aln": "MEAEEAQRGASPPISAIEEFSIIPEAPMRSSQVSALGLEAQEDEDPSYKWREEHRLSATQQSELRDVCDYAIETMPSFPKEGSADVEPNQESLVAEACDTPEHWEAVPQSLAGRQARTLAPPELWACPIQSEHLDMAPFSSDLGSEEEEVEFWPGLTSLTLGSGQAEEEEETSSDNSGQTRYYSPCEEHPAETNQNEGSESGTIRQGEELPPEELQES---QGLLHPQEVQVLEEQGQQEAGFRGEGTLREDVCADGLLGEEQMIEQVNDEKGEQKQKQEQVQD-VMLGRQGERMGLTGEPEGLNDGEWEQEDMERKAQGQGGPEQGEERKRELQVPEENRADSQDEKSQTFLGKSEEVTGKQEDHGIKEKGVPVSGQ-EAKEPESWDGGRLGAVG-RARSREEENEHHGPSMP-ALIAPEDSPHCDLFPGASYLMTQIPGTQTESRAEELSPAALSPSLEPIRCSHQPISLLGSFLTEESPDKEIDQNSQQEESRLRKGTVSSQGTEVVFASASVTPPRTPDSAPPSPAEAYPITPASVSARPPVAFPRRETSCAARAPETASAPLSMDDPSPCGTSEMCPAALYGFPSTGTSPPRPPANSTGTVQHLRSDSFPGSHRTEQTPDLVGMLLSYSHSELPQRPP--KPAIYSSVTPRRDRRSGRDYSTVSASPTALSTLKQDSQESISNLERPSSPPSIQPWVSPHNPAFATESPAYGSSPSFVSMEDVRIHEPLPPPPPQRRDTHPSVVETDGHARVVVPTLKQHSHPPPLALGSGLHAPHKGPLPQASDPAVARQHRPLPSTPDSSHHAQATP--RWRYNKPLPPTPDLPQPHLPPISAPGSSRIYRPLPPLPIIDPPTEPPPLPPKSRGRSRSTRGGHMNSGGHAKTRPACQDWTVPLPASAGRTSWPPATARSTESFTSTSRSKSEVSPGMAFSNMTNFLCPSSPTTPWTPELQGPTSKDEAGVSEHPEAPAREPLRRTTPQQGASGPGRSPVGQARQPEKPSHLHLEKASSWPHRRDSGRPPGDSSGQAVAPSEGANKHKGWSRQGLRRPSILPEGSSDSRGPAVEKHPGPSDTVVFREKKPKEVMGGFSRRCSKLINSSQLLYQEYSDVVLNKEIQSQQRLESLSETPGPSSPRQPRKALVSSESYLQRLSMASSGSLWQEIPVVRNSTVLLSMTHEDQKLQEVKFELIVSEASYLRSLNIAVDHFQLSTSLRATLSNQEHQWLFSRLQDVRDVSATFLSDLEENFENNIFSFQVCDVVLNHAPDFRRVYLPYVTNQTYQERTFQSLMNSNSNFREVLEKLESDPVCQRLSLKSFLILPFQRITRLKLLLQNILKRTQPGSSEEAEATKAHHALEQLIRDCNNNVQSMRRTEELIYLSQKIEFECKIFPLISQSRWLVKSGELTALEFSASPGLRRKLNTRPVHLHLFNDCLLLSRPREGSRFLVFDHAPFSSIRGEKCEMKLHGPHKNLFRLFLRQNTQGAQAEFLFRTETQSEKLRWISALAMPREELDLLECYNSPQVQCLRAYKPRENDELALEKADVVMVTQQSSDGWLEGVRLSDGERGWFPVQQVEFISNPEVRAQNLKEAHRVKTAKLQLVEQQA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RFG0-1", "uniprot_id": "A0A8M1RFG0_DANRE", "id": "A0A8M1RFG0-1", "name": "", "aln": "MDRER------------AMMQDSCDGTRERDRLPAIRRREMDWRE-RERWRDGDQYANGKS------------SLFEHTVHGERDKESKKGDTFPRMTKANRERDRRIPLSENERQRRLGRPKDTTYEDEKEREKRR--YRDMDTRRRMKEHSDKLREQEFELGIRGRRREGHTGTNDPTGMREKETDRERDRYRQRDREVRYYPRPIERETESFSDKE-----WRTERQNGAERSRKRDTKSEGD--------SDGDRGKEMNREAVTKPGHKLYKSEGDSKADQRVDRVREKDRRRDQEVWRYKEMVRPREKDYRETGYYDKNGMRKDKRPDRDAYSNTPERGRYRNAELE-KDGYSEREIEDRERWRRQNREPYRDKMEKSGQRTGGKISGVEIEKEHNRSVGENLEDRNRKNTSESEKEKLKGRTDGEQEVRIAPREEEGRQIVVEETVTKKFTGRIMNRWLEPRREKNPSLLEEDYRDR--ERARERYNQRFKESTKYEEDPARNNESKRTSAKDKYRAGEFMGDIDVESNEKLDKQEDMVNDKEAVEPEWRAKREIGGNNMEVNEREEERSIDRHDYSG----------IEEGSEGESRAEKDRIISADDGFVTVSSGGDIEDCMDFRNGEVPTDISGCSEATQGEEREPLRVFCVIGQTPIESQTKQNPYIDTASEEATDQHSDQNIDIQGVMFIEDANEAFEKFEHKESDIEGAMDDLALSANEEKVEQTGDNDQGTDDITSLKGQMIPSKEGAEEEPAEPSVTLDPCNDDGPETIVAPSEDALHRREMEATGNTEEHFDSDDTWSTCEERKRCSTAPHLTWAKNVVKEILGPNSEDTEHMRGSVTHIDIQINTQTETDREINISR-EHEELIQGEEKEQGEIEKESDEETILLDPSCIEQTVSSKREADRTVEGHVSKRKDSIENVILGSSSFRELGNEARIRRRGIR----KTTEGTKEEEEDEEEGGVGRDRRTRVFNNSDAE--------------EDELCLTWSE------------GDLRKLGRTKKRSSKYFNSQLYQEYSEVVQNREILLTNYDTTSLSGDNITIRSSSP---LNHSPKLSHRPLPALPQVHLHPHSLSLNNSLKSLN-----LPQQSINRPPSPRLSIS-----------ASSPTLWQDLPGVRNSPEIVELTEDERRLQEVRFEVVTSEASYCRSLDIVVENFVLSKQLNAILSSQDKNWLFSRLNDVRAISHSFMSHLEENVERDMLHFTVCDIIIKYCPRFRNVYVPYLTNQSYQDKTYQRLMDESQEFRRVVEKLERNPVCQRLPLRSFLILPFQRITRLKLLVQNIVKRTAPKTKDEVQAIKAMKLLEKMILDSNESISQMKNIESLVTLNAKVDFECRTLPLISQSRRLVREGPVTELRDFS---LKDREEERSVYMHLFNDYLLLSIRKEGGRFTVIDHAPVSELRAENCRFKLHSLQKNLFRLHMP------QKALLLRTDTQADNLRWISALSRPYPEIDFGAVQETPQMQCIRAYVAQQPDELSLEKADVLVVHQQSSDGWVEGTRLSDRQRGWAPELHLETITSDKARKRNLLDTMKIATAAM-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *. : :. . .::.*: . : .: :* : .: :. :: . . . ..: ... .: . : .. :. *: :.* . .:.. . * * . : . ...* .... : : : .. : : * .:. :.:. : *.. ::. . : .* *:: * . : :.: : : :. * .: .: : : . : . .: : .. .. : . . .*: : : : .. . * .. .*. . . : . * : . . . . *: *: *. : :: : ::::. * .:. . . * . : : . : :. . .:: * * ... * .: . : :.: : *:* . . * .. . . .. .. :. *:* .: . . : . * ** . . :. .* . :. . :.. .* :... *.::*.. . : .. *. *: .. .* : . :: . * . . .* .: * .. . : .:. * :. . . :. *: : ::. : : . :. . . . . . :: *.:: .: : * .: . :.: .. : :: * * .*. . . * . ... . . * . :*.. .: .. :: . : .. * : . : . . ..*.:.:*...* :. .: . : : : :: . .: **:.::* : . . * * :: *** :***::* ****. ::.:*.::::***.:**::.***** ***:*.*::* * .*.. **.*:::******:*** :* :*:*.****.*.::: * ***:::.:.. *:.**:**:***:**::*:* **:....**.*:**** :*:****.*:****************:***:*** * :.:*.:* ** : **::* *.*..:. *:. *.*: *. *::***: :******* **:.* :* *. *: : *.*::***** **** :**.** *:****.*.:*.*:*.:***. :******.: * :*:**:**:::*******: * *:*: ::**:**:*** .:: ***:******::* *******:**.**** ::** * ::* *:. :.* :** :: :: ** : ", "identical_positions": 287, "similar_positions": 487, "identity": "17.85%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-805", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AIY3-1", "uniprot_id": "A0A8I6AIY3_RAT", "id": "A0A8I6AIY3-1", "name": "Protein ABHD8", "aln": "MMSLKLDSVLTREGQRTGKGKGHTMLTGVTDGFFCCLLGTPPNAVRPLESVESSDGYTFVEVKPGRVLRVKHACPAPIPSPPPPPPEDNPGVK---TGLVRCQRRITVYRNGRLVVENLGRAPRADLQ-GRSGSGDPPGSLEVELAE----------PAG---GDTRATPGS----------GRRRRPRRPKRTIHIDCEQRITSCKGAQADVVLFFIHGVGGSLAIWKEQLDFFVRLGYEVVAPDLAGHGASSAPQVAAAYTFYALAEDMRAIFTRYAKKRNVLIGHSYGVSFCTFLAHEYPDLVHKVIMINGGGPTALEPSLCSIFNMPTCVLHCLSPCLAWSFLKAGFARQGAKEKQLLKEGNAFNVSSFVLRAMMSGQYWPEGDEVYHAELTVPVLLVHGMHDKFVPVEEDQRMAEILLLAFLKLIEEGSHMVMLECPETVNTLLHEFLLWE--------------------PEPEAEPKLEPKS--KPQPLQLQSDPAPGEEK-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0P8-1", "uniprot_id": "ABHD8_MOUSE", "id": "Q8R0P8-1", "name": "Protein ABHD8", "aln": "---------MTSE---------HTMLTGVTDGFFCCLLGTPPNAVRPLESVESSDGYTFVEVKPGRVLRVKHAGPAPIPTPPPPPPEDDPGVK---TGLVRCQRRITVYRNGRLVVENLGRAPRADLQ-GRSGSGDPPAALEVELAE----------PAG---GDTRANPGS----------GRRRRPRRPKRTIHIDCEQRITSCKGAQADVVLFFIHGVGGSLAIWKEQLDFFVRLGYEVVAPDLAGHGASSAPQVAAAYTFYALAEDMRAIFTRYAKKRNVLIGHSYGVSFCTFLAHEYPDLVHKVIMINGGGPTALEPSLCSIFNMPTCVLHCLSPCLAWSFLKAGFARQGAKEKQLLKEGNAFNVSSFVLRAMMSGQYWPEGDEVYHAELTVPVLLVHGMHDKFVPVEEDQRMAEILLLAFLKLIEEGSHMVMLECPETVNTLLHEFLLWE--------------------PEPEAEPKLEPKP--KPQ--LLQPEPAPGEEK-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96I13-1", "uniprot_id": "ABHD8_HUMAN", "id": "Q96I13-1", "name": "Protein ABHD8", "aln": "------------------------MLTGVTDGIFCCLLGTPPNAVGPLESVESSDGYTFVEVKPGRVLRVKHAGPAPAAAPPPPSSASSDAAQGDLSGLVRCQRRITVYRNGRLLVENLGRAPRADLLHGQNGSGEPPAALEVELAD----------PAG---SDGRLAPGSAGSGSGSGSGGRRRRARRPKRTIHIDCEKRITSCKGAQADVVLFFIHGVGGSLAIWKEQLDFFVRLGYEVVAPDLAGHGASSAPQVAAAYTFYALAEDMRAIFKRYAKKRNVLIGHSYGVSFCTFLAHEYPDLVHKVIMINGGGPTALEPSFCSIFNMPTCVLHCLSPCLAWSFLKAGFARQGAKEKQLLKEGNAFNVSSFVLRAMMSGQYWPEGDEVYHAELTVPVLLVHGMHDKFVPVEEDQRMAEILLLAFLKLIDEGSHMVMLECPETVNTLLHEFLLWE--------------------PEP--SPKALP-----------EPLPAPPEDKK----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PM00-1", "uniprot_id": "A0A8M9PM00_DANRE", "id": "A0A8M9PM00-1", "name": "Protein ABHD8", "aln": "------------------------MLTSFVDGIFCCFTGKSTNVVVPVESSEPTDGFEFVEVKPGRVLRVRHIIPDRPVVEEPGTGEG---------GTVSCKRKISVYRNGQLLIENVNEATHPELV--RYQNGDSTVDMEVSNCESPVVGQATETPAGGQAAETKPAPQE--------QQQVHRRRRKPKRSIVIDCERKITCCKGTHPDVALFFIHGVGGSLDIWRSQLDFFSQLGYEVIAMDLAGHGASSAPRIPAAYTFYALAEDVRIIFKRYAKRRNILVGHSYGVSFCTFLAHEYPEQVHKLVMINGGGPTALEPSLCSVFNLPTCVLNFLSPCLTWSFLMAGFAHQGTREKKLLKENNAFNVSSFVLRSMMSGQYWPEGDEVYHAEITVPVLLVHGMYDKFVPVQEDQRMAEILLLGFLKVLDDGSHMVMMECPDVVNTLLHEFFLWQPATASKPKQEAAPTKTNTKSPEDTSRPKTAPKSPSKSQPDLLRPTTAPKTTNIATEAPAVADIKSKGKK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***...**:***: *...*.* *:** *.:**: ************:* * * . . * * *:*:*:*****:*::**:..*.:.:* : .*:.. :**. .: *** .: : * . :** *:***:* ****::**.***::.**.*********** **:.***** :*****:* ***********::.***********:* **.****:**:*:*****************: ***::*************:**:**:*****: *****:**** ****:**::**:****.***********:*****************:**********:******:***********.***::::******:***:.********:**: ** ** * .. .** : ", "identical_positions": 275, "similar_positions": 95, "identity": "52.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-807", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70628-1", "uniprot_id": "PDE9A_MOUSE", "id": "O70628-1", "name": "High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A", "aln": "---------------------------------------MGAGSSSYRPKAIYLDIDGRIQKVVFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTP-YKVRPVAVKQVS------------------------------------------------------------EREELIQGVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLK--VVEIEKCKSDIKKMREELAARN-SRTNCPCKYSFLDN-KKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPITLRRWLLCVHDNYR-NNPFHNFRHCFCVTQMMYSMVWLCGLQEKFSQMDILVLMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAIAFQILARPECNIFASVPPEGFRQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHLTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEY---FMQSDREKSEGLPVAPFMDRDK-VTKATAQIGFIKFVLIPMFET--VTKLFPVVEETMLRPLWESRE-HYEELKQLDDAMKELQKK-TESLTSGAPENTTEKNRDAKDSEGHSPPN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8QZV1-1", "uniprot_id": "PDE9A_RAT", "id": "Q8QZV1-1", "name": "High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A", "aln": "---------------------------------------MGAGSSSYRPKAIYLDIDGRIQKVVFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTP-YKVRPVAVKQVS------------------------------------------------------------EREELVQGVLAQVAEQFSRAFKINELKAEVANHLAMLEKRVELEGLK--VVEIEKCKSDIKKMREELAARN-NRTNCPCKYSFLDN-KKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPITLRRWLLCVHDNYR-SNPFHNFRHCFCVTQMMYSMVWLCGLQEKFSQMDILVLMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAIAFQILARPECNIFASVPPEGFRQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHLTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEY---FMQSDREKSEGLPVAPFMDRDK-VTKATAQIGFIKFVLIPMFET--VTKLFPIVEETMLRPLWESRE-HYEELKQLDDAMKELQKK-TENLTSGATENAPEKTRDAKDNEDRSPPN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O76083-1", "uniprot_id": "PDE9A_HUMAN", "id": "O76083-1", "name": "High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A", "aln": "---------------------------------------MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATGLPRNTTISLLTTDDAMVSIDPTMPANSERTP-YKVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGLK--VVEIEKCKSDIKKMREELAARS-SRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYR-NNPFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEY---FMQSDREKSEGLPVAPFMDRDK-VTKATAQIGFIKFVLIPMFET--VTKLFPMVEEIMLQPLWESRD-RYEELKRIDDAMKELQKK-TDSLTSGATEKSRERSRDVKNSEGDCA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UT66-1", "uniprot_id": "A0A8N7UT66_DANRE", "id": "A0A8N7UT66-1", "name": "Phosphodiesterase", "aln": "MSSCIYFRRHLAGGTFEGWFWWICSWLRVQVDLTVHFINMGSASSSYSPKTIYLDVDGKVQKVLFSRHCSPCDIKELLCSSSNIPRNTAIMMTDPEGAIVSIDPTMPTNNPNFL-YKIIPLSASQLG------------------------------------------------------------EKEDMFQNVLSQVAEQFSRAFRINELKTEVTNRLAMLEKRVELEGLK--VVEIEKCKNDMRKLRDEMTSRAGARVNCPCKYNFSDDGKKLTPRRDIPSYPKYTLSQETIEALKKPTFDVWHWEHNEMLSCLEYMYHDLGLVKEFNINPITLKRWLLGIQENYR-SNPFHNFRHCFCVSQMMYGMIHLCNLQEKLTLTDLGILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILSLPECNIFANVEPEAFKQIRQAIITLILATDMARHGEILDSFKHKVDHFDFTNEEHVACLKMVLIKCCDISNEVRPTEVAEPWVDCLLEEY---FMQSDREKSEGLPVAAFMDREK-VTKPTAQIGFIKFVLIPMFET--VMKLFPQIEEIMVQPLRDSRD-HYEELKQIDDAMTEAQKKKTESLSLGGKKK------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P06776-1", "uniprot_id": "PDE2_YEAST", "id": "P06776-1", "name": "3',5'-cyclic-nucleotide phosphodiesterase 2", "aln": "-----------------------------MSTLFLIGIHEIEKSQTIVQNEHYFDRVIELQDLDSLMVALYKDRVSPFPNVHNFETGVSIVLYDPSKFQLSVRQLDVLFKRFFPSFNIS--AIDHTRE-----------------------------------------------------------ENLQRLECVERENSICRNRITRINHWMYHHHDDTPDGINKNSYGTVNGNSVPTQACEANIYTLLLHLNDSKAQHLRKASVPRLIRN-IEFMSFLSDPIEKISQEGSHYWNILSTWDFCALSLSTQELIWCGFTLIKKLSKDAKVLIADNKLLLLLFTLESSYHQVNKFHNFRHAIDVMQATW---RLCTYLLKDNPVQTLLLCMAAIGHDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHRELFQQLLSEHWPQLLSIS-----KKKFDFISEAILATDMALHSQYEDRLMHENPMKQIT-------LISLIIKAADISNVTRTLSISARWAYLITLEFNDCALLETFHKAHRPEQDCFGDSYKNVDSPKEDLESIQNILVNVTDPDDIIKDHPHIPNGQIFFINTFAEVFFNALSQKFSGLKFLSDNVKINKEYWMKHKKPQ---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.: : *:* .:*.: . * . : .: ..:* : .. :*: . ::: : .: *. : .: * : : .* :**. . : . :: . :: * : *: :: .: .: : . .. : : :: . . * . . : * . * . . :*:: * : :.*. .. * .* *: :...*: * ******.: * * : ** * . : :* **: **:.*** ** *..:*:* .::::* ***.* : *:*: :::: :: : : ******* *.: * : .: : : * ::**..**** .*. .:: *. : *: : . .*:. * * * * ... :: *: :*: : :. : * .* : : : : : :: *.: ..:. ..: . . .: ", "identical_positions": 85, "similar_positions": 172, "identity": "13.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-814", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V893-1", "uniprot_id": "ZN335_RAT", "id": "G3V893-1", "name": "Zinc finger protein 335", "aln": "MEENEVESSSDAAPRPGQPEEPSESGLGVGTSEAVSADSTDAATAPGLTEADDSGVGQSSDSGSRSVEEVSESIS-TEPLPQGYLPDSSSVSRGP----------VAEVPGGPPALVHSSALPDPSMLVSDCTAS-SSDLGSAIDKIIESTIGPDLIQSCITVTSGEEGGAETTQYLILQGPDDGAPMASSMSTSTLANSLAAIEALADGPTSTST-----------CLEPAE--------QPPGEPSS-----------------------------LAQ-PPAPVVEELDLQG---------------------------------------------------------------------------------------------------------------------------------------------------------LEAMMEVVVVQQFKCKMCQYRSSTKATLLRHMRERHFRPALAVAAAAAG--------KRGRVRKWGTSTKT------TEEEGPEEEEEDDDIVDAGAIDDLEEDSDYNPAEDEPRGRQLRLQRPTPSTLRPRRRPGRPRKLPRLETSDLHDGI--GEPLVSSQSTQSPPELQDLEAPSSSD---LRALGKVGRGLVETGVSQSDAENAAPS---CQDEADVPPRRRGRPSRRFLGKKYRKY-----YYKSPKPLLRPYLCRICGSRFLSHEDLRFHVNSHEAGDPQLFKCLQCSYRSRRWSSLKEHMFNHVGSKPYKCDECSYTSVYRKDVIRHAAVHSQDRKK-------RPDPTPKLSSFPCPVCGRVYPMQKRLTQHMKTHSTEKPHMCDKCGKSFKKRYTFKMHLLTHIQAVANR------RFKCEFCEFVCEDKKALLNHQLSHVSDKP---FKCSFCPYRTFREDFLLSHVAVKHTGAKPFACEYCHFSTRHKKNLRLHVRCRHANSFEEWGRRHPEEPPSRR-RPFFSLQQIEELKQQHSAAPGPPLSSAGP-EAPQEPAPFQPPETP--PLLCPDALGGATIIYQQGAEESTAMATQTALDLLLNMSAQRELGATALQVAVVKSEDVEAELTSTARQPS-SEDTTP---RVVTLHVAESGSSVAAESQLGPSDLQQIALPPGPFSGASYSVITAPPVEGRASASGPPYREEPPGEAAQAVVVNDTLKEAGTHYIMAADGTQLHHIELTADGSISFPSPDTLAPGTKWPLLQCGGPPRDGPEVLSPTKTHHTGGSQGSSTPPPATSHALGLLVPHSPPSAAASSTKKFSCKVCSEAFPSRAEMESHKRAHAGP--AAFKCPDCPFSARQWPEVRAHMAQ-HSSLRPHQCNQCSFASKNKKDLRRHMLTHTNEKPFSCHVCGQRFNRNGHLKFHIQRLHSIDGRKTGTSTARAPAQT----IILNSEEETLATLHTAFQSNHGTLGTERLQQALSQEHIIVAQEQTVANQEEATYIQEIT-ADGQTVQHLVTSDN---QVQYIISQDGVQHLLPQEYVVVPDGHHIQVQEGQITHIQYEQGTPFLQES--------QIQYVPVSPSQQLVTQAQLEAAAHSAVTAVADAAMAQAQGLFGTEEAVPEHIQQLQHQGIEYDVITLSDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A5K6-1", "uniprot_id": "ZN335_MOUSE", "id": "A2A5K6-1", "name": "Zinc finger protein 335", "aln": "MEENEVESSSDAAPRPGQPEEPSESGLGVCTSEAVSADSSDAATVPGLTEADDSGVGQSSDGGNHSVEEVSESIS-TDPLPHGCLPDSSSVSRGP----------VAEMPGGPPALVHSSVLPDPSMLVSDCTAS-SSDLGSAIDKIIESTIGPDLIQSCITVTSGEEGGAETTQYLILQGPDDGAPMASSMSTSTLANSLAAIEALADGPTSTSA-----------CLEPPE--------EPQGDPSS-----------------------------VAQQPPAPVTEELDLQS---------------------------------------------------------------------------------------------------------------------------------------------------------LEAMMEVVVVQQFKCKMCQYRSSTKATLLRHMRERHFRPALAAAAAATG--------KRGRVRKWGTSTKT------TEEDRPEEEEEDDDIVDAGAIDDLEEDSDYNPAEDEPRGRQLRLQRPTPSTPRPRRRPGRPRKLPRLETSDLHDGV--GQPLVSSQSTQSPPELQDLEAPSSSG---LRALGKVGRGLVESGVSQSDAENAAPS---CQDEADAPPRRRGRPSRRFLGKKYRKY-----YYKSPKPLLRPYLCRICGSRFLSHEDLRFHVNSHEAGDPQLFRCLQCSYRSRRWSSLKEHMFNHVGSKPYKCDECSYTSVYRKDVIRHAAVHSQDRKK-------RPDPTPKLSSFPCPVCGRVYPMQKRLTQHMKTHSTEKPHMCDKCGKSFKKRYTFKMHLLTHIQAVANR------RFKCEFCEFVCEDKKALLNHQLSHVSDKP---FKCSFCPYRTFREDFLLSHVAVKHTGAKPFACEYCHFSTRHKKNLRLHVRCRHANSFEEWGRRHPEEPPSRR-RPFFSLQQIEELKQQHSTAPGPPLSSPGP-EAPQEPAPFQSPETP--PLLCPDALGGTTIIYQQGAEESTAVATQTALDLLLNMSAQRELGATALQVAVVKSEGIEAELTSTGGQPS-PEDTTP---RVVTLHMAESGSSVAAESQLGPSDLQQIALPSGPFGGASYSVITAPPVEGRTSASGPPYREEPPGEAAQAVVVSDTLKEAGTHYIMAADGTQLHHIELTADGSISFPSPDTLAPGTKWPLLQCGGPPRDGSEVLSPTKTHHMGGSQGSSTPPPAASHTLGLVVPQSPPSAAASSTKKFSCKVCSEAFPSRAEMESHKRAHAGP--AAFKCPDCPFSARQWPEVRAHMAQ-HSSLRPHQCNQCSFASKNKKDLRRHMLTHTNEKPFSCHVCGQRFNRNGHLKFHIQRLHSIDGRKTGTSTARAPAQT----IILNSEEETLATLHTAFQSSHGVLGTERLQQALSQEHIIVAQEQTVTNQEEATYIQEIT-ADGQTVQHLVTSDN---QVQYIISQDGVQHLLPQEYVVVPDGHHIQVQEGQITHIQYEQGTPFLQES--------QIQYVPVSPSQQLVTQAQLEAAAHSAVTAVADAAMAQAQGLFGTEEAVPEQIHQLQHQGIEYDVITLSDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4Z2-1", "uniprot_id": "ZN335_HUMAN", "id": "Q9H4Z2-1", "name": "Zinc finger protein 335", "aln": "MEENEVESSSDAAPGPGRPEEPSESGLGVGTSEAVSADSSDAAAAPGQAEADDSGVGQSSDRGSRSQEEVSESSSSADPLPNSYLPDSSSVSHGP----------VAGVTGGPPALVHSSALPDPNMLVSDCTAS-SSDLGSAIDKIIESTIGPDLIQNCITVTSAEDGGAETTRYLILQGPDDGAPMTSPMSSSTLAHSLAAIEALADGPTSTST-----------CLEAQ------------GGPSS-----------------------------PVQLPPASGAEEPDLQS---------------------------------------------------------------------------------------------------------------------------------------------------------LEAMMEVVVVQQFKCKMCQYRSSTKATLLRHMRERHFRP-VAAAAAAAG--------KKGRLRKWSTSTKS------QEEEGPEEED-DDDIVDAGAIDDLEEDSDYNPAEDEPRGRQLRLQRPTPSTPRPRRRPGRPRKLPRLEISDLPDGVE-GEPLVSSQSGQSPPEPQDPEAPSSSGPGHLVAMGKVSRTPVEAGVSQSDAENAAPS---CPDEHDTLPRRRGRPSRRFLGKKYRKY-----YYKSPKPLLRPFLCRICGSRFLSHEDLRFHVNSHEAGDPQLFKCLQCSYRSRRWSSLKEHMFNHVGSKPYKCDECSYTSVYRKDVIRHAAVHSRDRKK-------RPDPTPKLSSFPCPVCGRVYPMQKRLTQHMKTHSTEKPHMCDKCGKSFKKRYTFKMHLLTHIQAVANR------RFKCEFCEFVCEDKKALLNHQLSHVSDKP---FKCSFCPYRTFREDFLLSHVAVKHTGAKPFACEYCHFSTRHKKNLRLHVRCRHASSFEEWGRRHPEEPPSRR-RPFFSLQQIEELKQQHSAAPGPPPSSPGPPEIPPEATTFQSSEAP--SLLCSDTLGGATIIYQQGAEESTAMATQTALDLLLNMSAQRELGGTALQVAVVKSEDVEAGLASPGGQPS-PEGATP---QVVTLHVAEPGGGAAAESQLGPPDLPQITLAPGPFGGTGYSVITAPPMEEGTSAPGTPYSEEPAGEAAQAVVVSDTLKEAGTHYIMATDGTQLHHIELTADGSISFPSPDALASGAKWPLLQCGGLPRDGPEPPSPAKTHCVGDSQSSASSPPATSKALGLAVPPSPPSAATAASKKFSCKICAEAFPGRAEMESHKRAHAGP--GAFKCPDCPFSARQWPEVRAHMAQ-HSSLRPHQCSQCSFASKNKKDLRRHMLTHTKEKPFACHLCGQRFNRNGHLKFHIQRLHSPDGRKSGTPTARAPTQTPTQTIILNSDDETLATLHTALQSSHGVLGPERLQQALSQEHIIVAQEQTVTNQEEAAYIQEITTADGQTVQHLVTSDN---QVQYIISQDGVQHLLPQEYVVVPEGHHIQVQEGQITHIQYEQGAPFLQES--------QIQYVPVSPGQQLVTQAQLEAAAHSAVTAVADAAMAQAQGLFGTDETVPEHIQQLQHQGIEYDVITLADD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BEI4-1", "uniprot_id": "A0A8M2BEI4_DANRE", "id": "A0A8M2BEI4-1", "name": "", "aln": "MDSEDMEVESSSDVGHSGMEEPSESGMGMESSEAMSADSSDAAAPPAPAPESDCHVGQSSEGLVVFIPETSSSTD----VRRVHLPDSSSVAQSTSVSSVSTVTQSVLVSESVQVLVHSSAVSEGGMMVSDSTASTSSDLGSAIDKIIESTIGPDIMNGCIAVTSAEDGSAETTQYLILQGPDDGAPMVAQMSSSALS-SRIAIEALADGPTSTCLDQPDLSENPQGNMEPDQPGHSGYREHDDGSSSSSRPDQPQHSQYIDPDQTREARYIQCSADEPDQTPRHSGVTDYNLADSEEPLQRYAAECSGTNDIPQRSSYRSSRYVVECSDGYLEYEADGEDRPQHSRYIDSSMDDREHVSASEQEGGALEEPQHSYMPQESLYADEGAVQHSLADTVGSQLNDQMDCSDNLPGPYISSSGTYSTNTEPEVVESGVVDEPGQRTPNMAELEEMMEVVIVQQFKCKMCPYKSVSKDTLINHMRDKHFKPAGSRSGGAVSHADGPGQRKRGRGRPRKSESKAGAVVVVKKEEQPEEEE--DDIVDAGALDDQG-DSDYKPADEEARSRLAVSHFTPPPSCSSSSPASTSRKRPRRMVGPPRKFLPDSESPAAPSETNNTEDPQAPEEASSSGLD-NGSSSFSNGTEVEPGVSQSDSENRDPSSNTSPDDLEFLPKKRGRPSKRFLQKKYKKYMNRNKYYRSLKPLLRPHNCWICGSRFLSQEDLKFHVDSHEGNDPERYKCLQCSYRCKRWSSLKEHMFNHEGTKPYKCEMCDYTSVYKKDVTRHSAVHNKSKSRKIDVSCVNPSQVSKVSEFPCPICSRVYPMQKRLTQHMKTHSTEKPHMCDKCGKSFKKRYTFKMHLLTHIQNCGNS------LFKCEFCDYTCNDKKHLLNHQLSHTNDKP---FKCEECKYSTSKEDFLVSHIAIKHTGEKPFSCEMCHFTTRHRKNLRLHVQCRHPETFEEWSRTHPDEPVRRRQTPVFTVEQIEELRLQHETQEFQGT------IVTVDPLTLQTMESIGNTSVSQDALGNTTIIYEQ--AQNSDLSAQNALDLLLNMSNAREL-----QVAVLKTDGKALETGSWSGSGSGSEGSSLQPQKIVTFHVSENGD-----------TLVQEAFETATGAVEQEETAVAQEVEQEVAQIG-----IGAYEGTDFSVVEQTSEET-THSSLEEPSAEPQVMEVSTEP-LSISTP--LKENKEKFYVSSG---------LTDGVLQQVELSSEAPASPPLS----------PSPHSQQLNTKRFSCRICMEAFHGRSDMENHKRAHIDP--KTFKCPDCDFTAPSWPEVKTHMAL-HAYLRPHKCTSCSFASKNKKDLRRHMMTHTNEKPYSCQVCGQRFNRNGHLKFHMERLHTQE--PSPRKARSVPSQQ---TIIINSDEEALATLQN-LQAGQAVISPERLQQALGQEHIIVAQDQSLSDQEEATYIQQITTVDGQTVQHLMTGDNQVTEVQYIISQDGVQHLLPREYVVVSDGNHIQMEDGQIAHIQYEHDGTFLQEQQIAVSQDGQIQYVPITTEQQVVAPEDLEAVAHSAVT---DTAMTQTV----YTEATPEQLEQLQQQGIQYDVITFTEE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W137-1", "uniprot_id": "Q9W137_DROME", "id": "Q9W137-1", "name": "C2H2-type domain-containing protein", "aln": "----MTVCVLCLDSSNAGYGLQSEEGVRLNIRATIHK---HFAFSEVLTAGGDAEVCRECWNCVSSFEEFHQRVS--------CLHRQR---------------------------------------SSDSKSEPIEFCGQTEEAIINPLYSVELDALAEAF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FAPSEVKVEVNELEPLPKVELLEDPVKTEIRTAPKRLGVPNE----------GSPHSKRR----------IKNELPVDSD--SDAPLADFLNSDSKRSSVGPAKNSEANKGRQLRRSARRGRPPKAKPESAPS-PKKELD--------SEDGEENARDNNDMEFVAPEAVLGTD-------------DSSSSSSESSGEDSDHS------LPDIEPEERYAEIPKRVVVKPKKYR------KREKPLVPPVR--------LSREEIERRKLQQDEYDEIILQFFKK----------------------FPCSLCNLLVQNFADMRRHQRVSHNIESG------------------YIECCGRKFHLRKALAEHVLVHKNPDHFMCSQCGRVFQDSRALEVHEQTHTNPEVKAEPKEKRIYQCEKCPKSFTTKAAMEYHDVSKHVPKSEFKYSCPECNKKIPTERKLKEHLRYMHDPEAAIICDKCGKTLRSQTNLKKHHELEHS----EKPRPKPDP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQCEICGTWLRHLSGLKQHMKTVHEPPGDEHRCHICNKTSTNSRALKRHIYHNHLCERKFKCGMCEKAFKRPQDLREHTSTHTGEVLYTCPNCPMTFFSNANMYKHRQRLHRAEWEADRK------------------------------------------------------------------------------------------------------KPLPPNIMKISQGATTAMKKRQTSGALFPQSEQKQ---------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VIS9-1", "uniprot_id": "Q9VIS9_DROME", "id": "Q9VIS9-1", "name": "Zinc finger protein weckle", "aln": "----MAAAQVEMHAAPAAPHVDRNPSSDWRQWCRLCAKDDVQGNLNVFLKNEDSGEAASMELATAIGKYFWVNIT----------------------------------------------------RGEELPETICSECLSLVTSLVNFSERITRVQKLYCILQS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPSQERPNLHELR--SKFGLLDEETQTEVHYVDKKPKLDEQ-----------------------------LEFLPEESP----YELANPLTPEEKQESVDQEQDQPTEE--------------------------------------PDEQDADYEPNEDRVLMSLCDVYGIQ---------------EDNSSAGSLDGSSPS---------------------------------------------------------------TEKAGEDAADSE---------------------------KRHQCNECLRSYATSKTLQRHLRQDHG-----------------------------------------QTEPTTEQLQCPDCPKKFRLHYQLERHMKWHVPLPKRK------QYACSSCDKKFATSASAQQHEQYMHLDER-----------------------------PRPVICEQCGVGVHSMSALKEHVLKHTDYAP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FECEVCKKCFKSANRLKHHKETHDPH---KYICPECGMQLNSRTTLNRHRLV-HTDQMQHKCDYCGREFKRAKALKNHLILHTGLKPYSCDFCDRTFANGSNCRTHKKKSHPEELAAQEAAGGGRSHNR------------------------------------------------------------------------------------------NIPKLEALKAFTKNKDNLSPVATKQSGCFAFGKKPR---------------------PATKDTPASNPAVIQDAQPEPAPDPGGENATQADTPAAAIPTLDNIYNHIMIDYR-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VH18-1", "uniprot_id": "Q9VH18_DROME", "id": "Q9VH18-1", "name": "Zinc finger protein weckle", "aln": "-----------MSDILAETQAANRDSTIWHQWCRLCSKEHPTNQNVFFREAKQN--SWASTMAMTIGKYFWVDIK----------------------------------------------------REDELSNFLCSECFTLMDCLIEFSERVRKVQILFSK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQLLQSNNLMDYEKIREDCGVATDGWKHIMLGAVDESLPQN----------------------------DEVFISEEQP-----IVCQTETSSKMKSEILMIPNFLVEKQCLQEKQDFPKEEDVIEEEMQISGVEEEILEEDVEEDLAEEEVETVEEEIDTVGEEVEAVEEELET-----------QDATDCLVEEVEHMTEDR-------------------------------------------------------YIEESQIIEESQVSDFNMETYEIVQHNPQ----------------KEPVETKDTVESIESNEDTQEDISREHVTDEE------------------------------------DEISEVPAMYKCNICKKPYKKPKAYKRHMEEVHNTVADDLP----QLECNQCKLCFPTVAQLHAHHRTHVRAKPKTDNCCPHCEKRFTTSGTLKRHIEGIHNQIKPYVCDLCGKSFNYITGLKDHKLVHTDECP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FECPVCKRGFKNNARLKIHLDTHSAE---IYECTVCGLKLKTRRTFNKHKLV-HSDTRQFKCEVCGSAFKRSKTLKAHLILHTGIRPYKCNFCGRDFANGSNCRSHKRQAHPKELAEEEARGVTRSTLLP-----------------------------------------------------------------------------------------MLDELTIASKLLKTPAGPCKVKGSRPKAAPKDQDNG------------------------------------------------NESPTKDTDGAILYELVEELDYS------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : : .: . ::: :: . : : .. . :. . .. : . : : . . : . . . : . .. * * : :: : * *. * *. : . *: * . . *: * . ..* :* : :: * : . * * .. * * .:* * *. : *: * ** : * * * ..: * .: * : . . . : : : ", "identical_positions": 29, "similar_positions": 79, "identity": "1.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-816", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O94829-1", "uniprot_id": "IPO13_HUMAN", "id": "O94829-1", "name": "Importin-13", "aln": "MERREEQPGAAGAGAAPALDFTVENVEKALHQLYYDPNIENKNLAQKWLMQAQVSPQAWHFSWQLLQPDKVPEIQYFGASALHIKISRYWSDIPTDQYESLKAQLFTQITRFASGSKIVLTRLCVALASLALSMMPDAWPCAVADMVRLFQAEDSPVDGQGRCLALLELLTVLPEEFQTSRLPQYRKGLVRTSLAVECGAVFPLLEQLLQQPSSPSCVRQKVLKCFSSWVQLEVPLQDCEALIQAAFAALQDSELFDSSVEAIVNAISQPDAQRYVNTLLKLIPLVLGLQEQLRQAVQNGDMETSHGICRIAVALGENHSRALLDQVEHWQSFLALVNMIMFCTGIPGHYPVNETTSSLTLTFWYTLQDDILSFEAEKQAVYQQVYRPVYFQLVDVLLHKAQFPSDEEYGFWSSDEKEQFRIYRVDISDTLMYVYEMLGAELLSNLYDKLGRLLTSSEEPYSWQHTEALLYGFQSIAETIDVNYSDVVPGLIGLIPRISISNVQLADTVMFTIGALSEWLADHPVMINSVLPLVLHALGNPELSVSSVSTLKKICRECKYDLPPYAANIVAVSQDVLMKQIHKTSQCMWLMQALGFLLSALQVEEILKNLHSLISPYIQQLEKLAEEIPNPSNKLAIVHILGLLSNLFTTLDISHHEDDHEGPELRKLPVPQGPNPVVVVLQQVFQLIQKVLSKWLNDAQVVEAVCAIFEKSVKTLLDDFAPMVPQLCEMLGRMYSTIPQASALDLTRQLVHIFAHEPAHFPPIEALFLLVTSVTLTLFQQGPRDHPDIVDSFMQLLAQALKRKPDLFLCERLDVKAVFQCAVLALKFPEAPTVKASCGFFTELLPRCGEVESVGKVVQEDGRMLLIAVLEAIGGQASRSLMDCFADILFALNKHCFSLLSMWIKEALQPPGFPSARLSPEQKDTFSQQILRERVNKRRVKEMVKEFTLLCRGLHGTDYTADY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K0C1-1", "uniprot_id": "IPO13_MOUSE", "id": "Q8K0C1-1", "name": "Importin-13", "aln": "MERREEQLGAAGAGAAPALDFTVENVEKALHQLYYDPNIDNKNLAQKWLMQAQVSPQAWHFSWQLLQPDKVPEIQYFGASALHIKISRYWSDIPTDQYESLKAQLFTQITRFASGSKIVLTRLCVALASLALSMMPDAWPCAVADMVRLFQAEDSPVDSQGRCLALLELLTVLPEEFQTSRLPQYRKGLVRTSLAVECGTVFPLLEQLLQQPSSPSCVRQKVLKCFSSWVQLEVPLQDCEALIQAAFAALQDSELFDSSVEAIVNAISQPDAQRYVNTLLKLIPLVLGLQEQLRQAVQNGDMETSHGICRIAVALGENHSRALLDQVEHWQSFLALVNMIMFCTGIPGHYPVNETTSSLTLTFWYTLQDDILSFEAEKQAVYQQVYRPVYFQLVDVLLHKAQFPSDEEYGFWSSDEKEQFRIYRVDISDTLMYVYEMLGAELLSNLYDKLGRLLTSSEEPYSWQHTEALLYGFQSIAETIDVNYSDVVPGLIGLIPRISISNVQLADTVMFTIGALSEWLADHPVMINSVLPLVLHALGNPELSVSSVSTLKKICRECKYDLPPYAANIVAVSQDVLMKQIHKTSQCMWLMQALGFLLSALQVEEILKNLHSLISPYIQQLEKLAEEIPNPSNKLAIVHILGLLSNLFTTLDVSHHEDDHEGPELRKLPVPQGPNPVVVVLQQVFQLIQKVLSKWLNDAQVVEAVCAIFEKSVKTLLDDFAPMVPQLCEMLGRMYSTVPQASALDLTRQLVHIFAHEPAHFPPIEALFLLVTSVTLSLFQQGPRDHPDIVDSFMQLLAQALKRKPDLFLCERLDVKAVFQCAVLALKFPEAPTVKASCGFFTELLPRCGEIESVGKVVQEDGRMLLIAVLEAIGGQASRSLMDCFADILFALNKHCFSLLSMWIKEALQPPGFPSARLSPEQKDTFSQQILRERVNKRRVKEMVKEFTLLCRGLHGTDYTADY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "X1WB88-1", "uniprot_id": "X1WB88_DANRE", "id": "X1WB88-1", "name": "Importin-13", "aln": "---------------MTAEEFTVEAVERALQQLYYDPDMGKKNVAQKWLSEAQASPQAWQFCWDLLRPEKVPEIQFFGASTLHAKISRHWSELPAGQLDSLRSQLMAQVGQFAAGPKMVLTRLCVALASLILHILPETWPTAVPDILCAFQTGEG--DGPSRCLALLELLAVLPEELQSSRIVTSRRSQLRSALAAHWSSVCRLLQQLLQQPDAPGRVRERVLRCVSSWITLDVCLQDSEGILESCFTLLKESEIFDAAVETIVCIISQPDCQRFVDSLLKVVPQVLALQEQLKKAVQDGDMETSHGICRIAVALGETHCRTLLEQVDHWQGFQALVSMIMSCTATPGHYPVDETSSSLTLTFWYTLQDDITSLDAERQTLYLQIYRPLYFQLVDVLLQKACFPRDEDFTAWSADDKEQFRTYRVDISDTLMYTYELLGPELLRNLYDKLGTLLTNSTHPSSWQDVETLLFGFQSIAETVDVSYSDVIPGLIGLIPLITANNIQLAETIMFTIGSLAEWLSDHSPMLANVLPVVLQGLSNPDLSVACVSALKRICRECRHDLHLHANDIIVVSQAVLVKDIHKSPQCMWIMQALGFLLSALPREEILGKLLSLVTPHIQQLEKLASEPPSSANKLLIVHILGLLSNLFSTFDLNKQSERLEVMRHVQT-QPLDNNPVVVVLQQAFPLIQTVLNKWLSDPEVVEAVCAVFEKSLKTLIHDFAPLVTQLCELIGQMFSAYPQASALDLTRQLVHIFACEKDLFSPITALLELITNITMSIFQLGSRDHPDVVESFMQLHTQVLKRKADLYLSDHLDIKAVFYCGILSFKFPETPTLKATCLLFTELISHYEDLPTVRDVLQEDGKLLLQTLLEAIGGQSPRSLAELLAEVLFSVSRNCPSLLTLWLRDALLPSGFPSSHLTAEHKEHFCQQILREQVSKRQMKDIVKEFALLSRGLQGTEYAANY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* :**** **:**:******:: :**:***** :**.*****:*.*:**:*:******:****:** ****:**::*:.* :**::**::*: :**:*.*:************ * ::*::** **.*:: **: :. *. .*********:*****:*:**: *:. :*::**.. .:* **:******.:*. **::**:*.***: *:* ***.*.::::.*: *::**:**::**:** *****.**:*::***::* **.*****::***:******************.*.*:**:**:***.* ***.*** **. ******:**:*************** *::**:*::* *:***:*********:** ** **:: **:*:***** ***********.**:**.*** ******* ***.* .* ***..*:**:********:**.****:******** *: .*:***:*:*****:*:***:**. *: .***:**:.*.**:***:.**:**:*****::** :* :*:.*** **:*:***:.****:*********** **** :* **::*:********.* *..:*** ************:*:*:.::.: * . : * . *********.* ***.**.***.*.:*******:****:***:.****:*.****::*:*:*: ***************** * *.** **: *:*.:*:::** *.*****:*:***** :*.****.**:*.::**:**** *.:*::****:**:**:* :****:.: :: :* .*:****::** ::*******:.*** : :*::**::.::* ***::*:::** *.****::*:.*:*: *.******:*.**::*::****:**.***:**:*:*:*", "identical_positions": 589, "similar_positions": 267, "identity": "61.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-818", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q69Z69-1", "uniprot_id": "ESCO1_MOUSE", "id": "Q69Z69-1", "name": "N-acetyltransferase ESCO1", "aln": "---------------------------------------------------------------------MSIQEKSKENSSIVTKESEDENL------------------EEEVESSQNSPTKKSGSKEAVKTPVRFSNKSKTNESEFGMRMSTRSASCSADKTATNSFNKNTVTLKGQSQESSKTKKLCQEK--------LSLGILKGNEQLHRRSQRLQQLTECTTRSLRSREIHGQIQTVKQNQQSARREQCNSTQSKCNKVKVNQKHVKRKVLEIKSDCKEDRHSVTNEVINSPKGKKRKVQHQTTSTCSSQCNQGSEKCLQKTSRKEEIKPVPVTADIRKLKAATS----------------------------VVSKKNELRKSAHTQVSTSTKRPQ----------------IPLPLVPEHSDDQELEQAGKSKRG-----SILQLCEEIAGEIESDT---------------VEVKKE-----------------------SSCVESVKEEKPAEVKLQGTDAERQILHHKEANQDVRSNRFFPSRKTKPVKCVLNGINSSTKKNSNWTKIKLSKFNSVQQHKLDS--------QVSPKLNLLQTGLSTSVLEMPHPVSQS---TFLEMKAHG-NVTCQRDKMKGIKSEEVKINNIAIEINKATKRDPGNCNLDN--HIKPSPDSSLDNQMKLSCES--APDQNFSICSASEVETNPLENTAAASTLLSQAKIDE-DRTFPGSAPNQQHSVLSDEASINRKNRDVPPNHSQLKHDSHLEITIPKSLKLKDSEKVDEK---------------------------------QLVIDAGHKRFGAVSCNICGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILAEYP----DGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYS-----RTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNTT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5FWF5-1", "uniprot_id": "ESCO1_HUMAN", "id": "Q5FWF5-1", "name": "N-acetyltransferase ESCO1", "aln": "--------------------------------------------------------------------MMSIQEKSKENSSKVTKKSDDKNS------------------ETEIQDSQKNLAKKSGPKETIKSQAKSSSESKINQPELETRMSTRSSKAASNDKATKSINKNTVTVRGYSQESTK-KKLSQKK--------LVHENPKANEQLNRRSQRLQQLTEVSRRSLRSREIQGQVQAVKQSLPPTKKEQCSSTQSKSN--KTSQKHVKRKVLEVKSDSKEDENLVINEVINSPKGKKRKVEHQTACACSSQCTQGSEKCPQKTTRRDETKPVPVTSEVKRSKMATS----------------------------VVPKKNEMKKSVHTQVNTNTTLPK----------------SPQPSVPEQSDN-ELEQAGKSKRG-----SILQLCEEIAGEIESDN---------------VEVKKE-----------------------SSQMESVKEEKPTEIKLEETSVERQILHQKETNQDVQCNRFFPSRKTKPVKCILNGINSSAKKNSNWTKIKLSKFNSVQHNKLDS--------QVSPKLGLLRTSFSPPALEMHHPVTQS---TFLGTKLHDRNITCQQEKMKEINSEEVKINDITVEINKTTERAPENCHLAN--EIKPS-DPPLDNQMKHSFDS--ASNKNFSQCLESKLENSPVENVTAASTLLSQAKIDTGENKFPGSAP-QQHSILSNQTSKSSDNRETPRNHSLPKCNSHLEITIPKDLKLKEAEKTDEK---------------------------------QLIIDAGQKRFGAVSCNVCGMLYTASNPEDETQHLLFHNQFISAVKYVGWKKERILAEYP----DGRIIMVLPEDPKYALKKVDEIREMVDNDLGFQQAPLMCYS-----RTKTLLFISNDKKVVGCLIAEHIQWGYRVIEEKLPVIRSEEEKVRFERQKAWCCSTLPEPAICGISRIWVFSMMRRKKIASRMIECLRSNFIYGSYLSKEEIAFSDPTPDGKLFATQYCGTGQFLVYNFINGQNST", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BLF3-1", "uniprot_id": "A0A8M2BLF3_DANRE", "id": "A0A8M2BLF3-1", "name": "", "aln": "---------------------------------------------------------------------MPGQKRKMSSSEPEVKKTKLDRN------------------LVESDKSQKPKRGRPPKSKVLEAQPSRQKHQIDSREENGKPIRRSSRLKTPLKKGARARRRKDGEKPKVSEEKSSQKMPVLKKGNKKYVSRVKREKPIISETIKTVAAMFPVQIEHNYGRLFDMQAEEITLPKPDKIHVANKSEMQALHETQASKAEEQKELHAEPVEKITVSVDAKVDVMSKSPPPLEALFKVIQESSLTKHSFSGKDISDMDELEVVNTCSLQDSVQSTDVAKVFLQDSDAFLDDDVEIENCVVEIETYEDLDGDQGEVSKKQTSECVTCKEVNSSPSLPQESATDSSQELPKKQAMNPQARTKARLAALAEERAAAAKKPPPRHFNLLALCEEIADDIASDAPGASDKTTNEQQQEDHESEDV-----------------------SECTEVSESKDASESKEVNESKDLSESKDASESKDVSENKEVSETETCEPEEVVSENTAPPGTPNEETADPRPEDGTPKKRFFLS--------QMSVPLKTQEKKKLSRFQRLRQVELQRDKLTWTRVKKLKSDQVNQAGSQKDSEASSVSPSPATTPAQVPTTESVPKVGSVEPKRVLPAQAPPMPNGITSPKPKPVVEYKPYTPRRKYSPDDFELDGFEEDTAKPAAPKNVGKAEQSPSSAKVQPNPAVERKLCVPTTADSKSKSSPQQETAQQTQLENSNSSSVEPEQKKEDKNSPKP-----------------------ESPAAQSSNEAGQKAFGAVTCNVCGMLYSPTSAEDESQHLLFHNQFISAVRYVGWKKERILGEYP----DGKIILVLPDDPKYALKKVEEIREMVDNDLGFQQVESKVPS-----QTKTFLFISNDKKVAGCLIAEHIQEGYRVIEESVLEG-SEGEKVMYERQRAWCCSTVPEPALCGISRIWVFSMMRRRGIASRMIECLRNNFIYGSHLSKDEIAFSDPTPDGKLFATHYCGTSQFLVYNFVSGKRST", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43605-1", "uniprot_id": "ECO1_YEAST", "id": "P43605-1", "name": "N-acetyltransferase ECO1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKARKSQRKAGSKPNLIQSKLQVNNGSKSNKIVKCDKCEMSYSSTSIEDRAIHEKYHTLQLHG-----------------------------------------------------------RKWSPNWGSIVYTERN-HSRTVHLSRSTGTITPLNSSPLKKSSPSITHQ----EEKIVYVRPDKSNGEVRAMTEIMTLVNNELNAPHDENVIWNSTTEEKGKAFVYIRNDR-AVGIIIIENLYGGN-------GKTSSRGRWMVYD-SRRLVQNVYPDFKIG-ISRIWVCRTARKLGIATKLIDVARENIVYGEVIPRYQVAWSQPTDSGGKLASKYNGIMHKSGKLLLPVYI--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VS50-1", "uniprot_id": "ECO_DROME", "id": "Q9VS50-1", "name": "N-acetyltransferase eco", "aln": "METPTGSGRPSRMATPRLSERKRQLFGSPRSRLRQINDDEDDADVDSLGVLPLKTHVAANRKGRSLFAAVPGKSSSSANSSPETNKENKKTRGGVMTATAEQLPQLFTATMRLNSNSSSNSRNSSPRQTRVQRKRADSSMSSPTSSSEGTPSSRARNSIRRSPRTFSAQKDPDAFSSPESFQTRLSKVAAMLMKGQDSRSMLEKSKKKHNHSLKTTAQVHTTKPKKTSPAEESQSDDEKPSSSKNSRKNTEVRETRSSQIISPKTRNRRRPFTSADINCKTLKAAAHLHENMRSYDEEKTAAVKLENSRSRSKSPVEVFKSNDDAVKRNTGNTNNKTAKSSEVATAKRPESPGSSMKIDVEVPESDEEASNHKPQKRQHPETSTPVAPSADADSGSPQSKMRKVTLSSSIPTMAFYSHSGEAVTKSRRRPSISKNSLKQPTKISPTSRPLLGINKGVHHKIRKRHGFANRLPATDMDNILNSLSNERLKNLITTKREERAKVEEVHQILRNAKDPIKMAKPLSVIEADDANNNNNLPATAWQETSADFSDLSDVEDIDPIIEVEPIIPIIRHEPVQKSPTAEPADLSKRKFFKSGRRSSTCMEVRITDNIRASVSQGKIELVQTIRRKPRQVRVKSATIFSAEQATVDAILKNLDDTVVDEIVEANPVVQATPIDAEETTMETESLPDIIEYAPEANDVEIDPFAEFRQRLPYQTDDPNVVEQQQILLEFLISNNICTEKNFEIFIANPDDYKDEANQIVDNLYMVVNSEEAAQLAQMETVENTAVAIAPKQDAPAVEEVQPKLFPIFTQRLQPVVQKSLRRRPDTSMRLLTAAGGSNQYQIDAGQKAFGARQCQQCGLVYTVHEPEEELLHREYHN-SIHVLRFKGWIDEDIVSVYPEWASDGRIIRINERAPTARLDRLRDLIGVVDKELGYSSYIVPKIF--------VAFIAVRKQQIVGFCLVQPLSQAHR----------------FIQVDGTDYFSEESYPASCGVSRIWVSPLQRRSGIASKLLRVVQCHTVLGQEIARECIAFSTPTDDGRALARQFTGLDNFLTYDQ-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * . : : :. : : .::*: . ... * . * :. .. : : :*: : .. : : :: :*:::*. . . ..: .* : : : . : . . . :***** *: **:::: : : : *. :.: :*:* ** .* :* :: * : ", "identical_positions": 24, "similar_positions": 72, "identity": "2.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-819", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9C0D5-1", "uniprot_id": "TANC1_HUMAN", "id": "Q9C0D5-1", "name": "Protein TANC1", "aln": "MLKAVLKKSREGG-KGGKKEAGS---------DFGPETSPVLHLDHSADSPVSSLPTAEDTYRVSLAKGVSMSLPSSPLLP-RQSHLVQSRVNKKSPGPVRKPKYVESPRVPGDAVIMPFREVAKPTEPDEHEAKADNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEDKNETMCTALSQGISPCSTLTSSTASPSTDSPCSTLN--------SCVSKTAANKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGSSLEWNKDGNLRLGVQKG-VLHDRRADNCSPVAEEETTGSAESTLPKAESSAGDGPVPYSQGSSSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWH-NTAGGRAQEVKARFAPYKPQDILLKPLLFEVPSITTDSVFVGRDWLFHQIEENLRN-TELAENRGAVVVGNVGFGKTAIISKLVALSCHGSRMRQIASNSPGSSPKTSDPTQDLHFTPLLSPSSSTSASSTAKTPLGSISAENQRPREDAVKYLASKVVAYHYCQADNTYTCLVPEFVHSIAALLCRSHQLAAYRDLLIKEPQLQSMLSLRSCVQDPVAAFKRGVLEPLTNLRNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIISKFPAWLKLIVTVRANFQEIISALPFVKLSLDDFPDNKDIHSDLHAYVQHRVHSSQDILSNISLNGKADATLIGKVSSHLVLRSLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFERALPILNVALASLHPMTDEQIFQAINAGHIQGEQGWEDFQQRMDALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTAFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKKTGISSSHLQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGTSENGMTALCYAAAAGHMKLVCLLTKKGVRVDHLDKKGQCALVHSALRGHGDILQYLLTCEWSPGPPQPGTLRKSHALQQALTAAASMGHSSVVQCLLGMEK-EHEVEVNGTDTLWGETALTAAAGRGKLEVCELLLGHGAAVSRTNRRGVPPLFCAARQGHWQIVRLLLERGCDVNLSDKQGRTPLMVAACEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAAIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTSVVVALLRKGAKLG----------NAAWAMATSKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYALRKFPREGFGEDMRPFNELRVSLYLNLSRCRRKTNDFGMAEEFASKALELKPKSYEAFYARARAKRNSRQFVAALADLQEAVKLCPTNQEVKRLLARVEEECKQLQRSQQQKQQGPLPAPLNDSENEEDTPTPGLSDHFHSEETEEEETSPQEESVSPTPRSQPSSSVPSSYIRNLQEGLQSKGRPVSPQSRAGIGKSLREPVAQPGLLLQPSKQAQIVKTSQHLGSGQSAVRNGSMKVQISSQNPPPSPMPGRIAATPAGSRTQHLEGTGTFTTRAGCGHFGDRLGPSQNVRLQCGENGPAHPLPSKTKTTERLLSHSSVAVDAAPPNQGGLATCSDVRHPASLTSSGSSGS-PSSSIKMSSSTSSLTSSSSFSDGFKVQGPDTRIKDKVVTHVQSGTAEHRPRNTPFMGIMDKTARFQQQSNPPSRSWHCPAPEGLLTNTSSAAGLQSANTEKPSLMQVGGYNNQAKTCSVSTLSASVHNGAQVKELEESKCQIPVHSQENRITKTVSHLYQESISKQQPHISNEAHRSHLTAAKPKRSFIESNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0VGY8-1", "uniprot_id": "TANC1_MOUSE", "id": "Q0VGY8-1", "name": "Protein TANC1", "aln": "MLKAVLKKSREGG-KGSKKEAGG---------DFGSETP---ALSSSGDSPVNSLSTTEDTYRVSLAKGVSMSLPSSPLLP-RQSLLTQSRSNKKSPGPVRKPKYVESPRVPGDPVMIPFGEGSKPSEPSATEAKADNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEDKNEAMCTALSQGISPCSTLTSSTASPSTDSPCSTLN--------SCVSKTAASKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGSSLEWNRDGSLRLGVQKG-VLHDRRADNCSPVAEEETTGSAESVLPKAEPSAGDGPVPYPQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWH-NTAGGRAPEVKARFAPYKPQEILLKPLLFEVPSITTDSVFVGRDWLFHQIEENLRN-TELAENRGAVVVGSVGFGKTAIISKLVALSCHGSRMRQIASSSPSLSPKSSDPTQDLPGTPLLSPSSSTSALSVTRTPAGPGTADSQRPREDAVKYLASKVVAYHYCQADNTYTCLVPEFVHSIAALLCRSHQLAAYRDLLIKEPQLQSMLSLRSCVQDPVAAFKRGVLEPLTSLRNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIIPKFPTWLKLIVTVRANFQEIISALPFVKLSLDDFPDNKDIHSDLHAYVQHRVHSSQDILSNISLNGKADAALISKVSSHLVLRSLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFDRALPILNVALASLHPMTDEQIFQAINAGHIQGEQGWEDFQQRMEALSCFLIKRRDKTRMFCHPSFREWLVWRADGESTAFLCEPRNGHALLAFMFSRQESKLNRQQTMELGHHILKAHIFKGLSKKTGVSSSHLQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGMSENGMNALCYAAAAGHMKLVCLLIKKGARVDHLDKKGQCALVHSALRGHSDILQYLLNCEWSAGPPQPGTLRKSQALQQALTAAASMGHSSVVQSLLGMAE-EHEIEVNGTDTLWGETALTAAAGRGKVEICELLLERGAAVSRANRRGVPPLFCAARQGHWQVVRLLLDRGCDVNLSDKQGRTPLMVASCEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAEIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTAVVVTLLRKGAKLG----------NAAWAMATSKPDILIILLQKLVEEGNVMYKKGKMKEAAQRYQYALRKFPREGLGEDMRPFNELRVSLYLNLSRCRRKTNDFGLAEEFASKALELKPKSYEAFYARARAKRNSRQFLAALADLQEAVKLCPNNQEIKRLLARVEEECKQLQRNQQQKQQGPPPAPANDSDNEEDAPASSLKDHFPIEEAEEEDTSSQEESISPTPRSQPPPSVPSPYIRNLQEGLQSKGRSASPQSRAGISKSLRETVAQSGLVMQPTKQAQIVKTNQHLGSGQSSMRNSSTKIQVSSQNPPPSPMPGRVSAAPAVSRNQHLEGTGPFTAGTGCGHFGDRLGASQSLQLQRSESGTAYPLPSKVKAAERLLAHASVAVDMAPPNQGGPVSCSDVRHPASLSSSGSSGS-PSSSIKMSSSTSSLTSSSSVSDGFKVQGPDSRIRDKGTTQVQGGTAEHRPRNTPFMGIMDKTARFQQQSNPPNRSWHCPVAEGLLTNTATAAGLQ-SNSEKP-TLKPGGYCSQAKPCSVPPLSMGVHNGAQVKELEENKCQIPALCQDNRITKGVPHLYPEGVSKQPLHVSTEAHRSHLTSAKPKRSFIESNV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F6L6-1", "uniprot_id": "E7F6L6_DANRE", "id": "E7F6L6-1", "name": "", "aln": "MFKAVLKKGREGGGRASKRDAGSQPLSPSFHQRFEEQGIVGVQDRGSVLLPVQPYP-AEEMLRPSLTRGVSVSLPSSPLLPPRQPYLSPVRTNK-SPGSIRTPKYVENLCVPGAPVTCSLKNRKK----SNTELLSPAESGSSPAVQELMTRLGFLLGDAIPTSSQTNMEDKQ---CIVSSQGVSPCSTLTSSTASPSAESPCSTLPESSSNSRAPVICSSACSTATSTVITTPSSTLESKDSGIIATVTSSSENEERCGSSLEWAKDGGAGVRGESGRSCIPITPEEPTVSSEVQPRTSSTGGAAPVVTSPLDGPITYH--SASLVMPRPNSVAATSSTKLEELRYLDEQRNAPQRSSMRLPWHGAHTGGRSQETKARLTPYKPVDIMLKPLLFEVPSVSMDAVFVGRDWLFQRLEEVLAGGGDADEGKGAVIIGNVGFGKTAVISRLVALSCHGGRMRQIASSSPEATPQNRG--SDAAQSSQLNPAS----QSPIRCPS---TPETHRHREGAVKRLAGKVVAYHYCQADNTYTCLVPEFVHSVSALLCRAPLLNAYRELLLRETHLQSLLSLRSCVQDPAAAFRKGVLEPLTLLRKERKIPEEDYIILVDGLNEAEFHKPDYGDTIASFVTKIISKFPVWLKLIVTVRANLVEVTNLLPFPVISLDDFHDNKDITSDLTSYIQQRIDHSPDIISNIAINGKADPANISKLSSHLIARSQGSYLYLKLTLDLFEKGHLVIKSSSYKVIPVSLSELYLLQCNMKFPSASAFERVLPLLNVALASLHPLTDEQLFRALNAGFMTGELEWEDFQQRMDALSCFLISRRDKTRMFCHPSFREWLVWRADGESTDFLCDPRSGHALMAFMLSRQEGKLNRQQTMELGHHILKAHIFKGHSKRTGVSSSVLQPLWISYSTDSLSAALSSLRNLYTPNVKVSRLLILGGASVCYRTEVLNSAPVLCVQSHLGHLEMAALLLESGAPVDGQSENGMTSLCYASAAGHLPLVTLLCKKGAKVDHADKSGQCALVHAALRGHAEILQYLLEQDWSSD-------LKNKALQQALIAASSMGHTQVVKKMLALNNDEFSVQIDGHDTLWGETALTAAAGRGKQEGCVFLLDQGAIVTQPNRRGVAPIFNAVRHGHTQIAELFLQRGADVNCGDKHGRSLLMVAASEGHLETVDFLLSKGACLTAVDKEGLTPLGWACLKGQKKVVEFLVDRGAQIDHTDKHGRTPLDLAAFYGDADIVHYLVECGAAIEHMDYSGMRPLDRAIGSRNTSVVVTLLKKGAKLGYRTSPYERSGNAAWAMATSKPDILIILLQRLMEEGNLLYKKGKMKEAAQRYQYALRKFPREGFGEDLKAFRELRVSLYLNLSRCRRKTNDFGMAEEFATKALELKPKSYEAFYARARAKRSSRQFAAALADLYEAARLCPSNREIRRLLARVEEECQHLQRQGSKHPTSHGNPSHHEDDNEND------------DEEDDDEVEDDDQDIESLEKS------PDSLSINMLQADDEEERREQESSRQDKRK-------------ESWHQSRTLPDSLCLALS-------------DAQSAISTAAPGRVAHRRLPSRQAQSMKNREYSS-------------SLHAEGRTPQSAGSSPMPSRHRPTS---LRAGPCIDIGGLDRSPLGDAREGGIQFSLAEKAEINIEPREFCRSSSVRVSSSSSGNLTD-------TSRLRN-SMASAPDRQSEHKPR--PFMGVIDKTARFQQQQQ---QSHHG----SLVSSYGWPEGLVGHNVGVVVNTHSQGLTSDLQYSKSSAYQEPIHNSTLTTEFHSG--------AGYKDTNPLQQHYNDTKHKQASLAR--DNPILISSIKPKRSFIESNV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:******.**** :..*::**. * : * **.. . :*: * **::***:********* **. * * ** ***.:*.*****. *** .* .: : * . * : *...***.***:********:.**:::: .:***: * . ***:**************::****** . :..:*...:.. .*::***************:******::*.****** :**. : :.* .:: : :* :. *: . . . .*. ***:.* *.**:****************:* *** ***** *:*:***** :***: *.***::**** :*:**********:: *:*********:::** * . : *.:***::*.*******:**:********.*******.** :*:. . .* :. *.*:* * : * :.:.:* **.*** **.************************::*****: * ***:**::*.:***:**********.***::******* **:*:*****:****:****************::**:****.***.***********: *: . *** :***** ***** *** :*:*:*:. * **:***::*****.: *.*:****: ** *************::*******:****:**************** : ***:*.**:**********:****:*:*:***.: ** ********:*******.************************.* ***:**.****:***:****.********************** **:**:*** **.***.***:.*****:*********************.* *******.**:********* *:.:**** ** :** *****.:****:****: ** ** ***.:*** **.*******:*****.:****** :**.. *.:****** **:****:.**: :*.: : *..::::* ***************** * * :** :** *::.*****.*:* *.*:** *:..*:*:**.*** .**:**: ****:.****.**:*******.*:::*****:.*.******:: **::**:.** **:***:**************: * **** **.***:*:***********.***:***:**:****** *******************:*:****::************************:***::.*.*********************:*****:*********************.**** ****** **.:***.*:*::**********::***. .:: . .. ::.:**:* :* ::::.. :::.:.. :* *.. *: :. :.: * . .** . * :. :*:: : . *. . .:*.. .:. ***:: ** : . ::: * . : :.. : *:**: :.:. ::. .:* . ::. . : **:.... . * . : ** * :**...:* :*::: : . . :**:** ****::*********.: :* * .*::. . . ** * : * .: : .. .. . :**.: ..*:... : *: : : * : ** : ::: ***********", "identical_positions": 1021, "similar_positions": 442, "identity": "53.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-823", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZA46-1", "uniprot_id": "D3ZA46_RAT", "id": "D3ZA46-1", "name": "", "aln": "-MDSTETELTPAPEG---------RKRYSDIFQSLDNLEISLGNVTFDPLAG--DLVLREDLEPDKTDTAAVETEENSEAS-WSNPSPEGP-----APLTEEELDLRLIRTKGGVDAALEYAKAWSRYAKELLAWTDKRANYELEFAKNIMKIAEAGKGSILQQSQMPLQYIYTLFLEHDHSLGALAIDTVAQQKRDYYQPLAAKRMEIEKWRKEFKEQWLKEQKRMSEAEQALRRSQLQYIQRREDLRARTQGSPEDPPLQASPGSNKQQERRRRSREEAQAKAHEAEALYQACVREANTRQQDLETTKR-RIVSHVRKLVLQGDEVLRRVTLGLFELRGAQAERGPRSFSALAECCVPFEPG---QRYQEFVRSLQPGAPPPPSPAFCFQEFAPVVHSFPQDTKKKFSGPLPTRLEE-GPSEPGPWEVASLGS--QGIP----GSDVDSVGGGSESRSLDSPTSSPGAGARRLVKASSTGTESSDDFEERDPDLG-DGMENGTGSPFRKWTLSTAAQTHRLRRLRG-PAKCRECEAFMVS-GTECEECFLTCHKRCLETLLILCGHQRLPARMPLFGVDFLQLPRDFPEEVPFVVTRCTAEIEHRALGLQGIYRVSGSRVRVERLCQAFENGRALVELSGNS-PHD------ITSVLKRFLQELTDPVVPFHFYDAFISLAKTLHADPGDDPGTPSP--SPEIIRSLKTLLVQLPDSNYSTLRHLVAHLFRVAARFKENKMSANNLGIVFGPTLLRPPDGPGATSASPVACLLDSGHQAQLVEFLIVHYEQIFG------MDELPLTSEPLTQDPALAPALLE-SSPQHPALLVAQDSQPLTIASDSSP-DPKQHSALEKCPKVAPPELTALQSNRKEEEEEDTRDGAGDGSSHSPEDLLLVAQSRGHFSRQPVKYSRGG-----VRPVTHQLSS-----------------------------LALVASKLCEETPITVSAVHRGSLRARGLGPAAASPEGGTLRRNPLPKHFEITQETARLLSKLDSEAVSRTSCCADPE----PEESEEHL---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PGG2-1", "uniprot_id": "GMIP_MOUSE", "id": "Q6PGG2-1", "name": "GEM-interacting protein", "aln": "-MDSAETELTPAPEG---------RKRYSDIFQSLDNLEISLGNVTFDPLAG--DPVRREDLEPDKADTATVVTEENSEASSWRDLSPEGP-----APLTEEELDLRLIRTKGGVDAALEYAKAWSRYAKELLAWTDKRANYELEFAKSIMKLAEAGKVSILQQSQMPLQYIYTLFLEHDLSLGALALETVAQQKRDYYQPLAAKRMEIEKWRKEFKEQWLKEQKRMNEAVQALRRSELQYIQRREDLRARSQGSPEDPPSQASPGSNKQQERRRRSREEAQAKAHEAEALYQACVREANSRQQDLETTKR-RIVSHVRKLVLQGDEVLRRVTLGLFELRGAQAERGPRSFSALAECCVPFEPG---QRYQEFVRTLQPGAPPPPSPAFCFQEFTAVVHSFPQDTKKKFSGPLPPRLEEEGSPEPGPWEVASLGS--QGIP----GSDVDSVGGGSESRSLDSPTSSPGAGARRLVKASSTGTESSDDFEERDPDLG-DGIENGVGSPFRKWTLSTAAQTHRLRRLRG-PAKCRECEAFMVS-GTECEECFLTCHKRCLETLLILCGHRRLPARMSLFGVDFLQLPRDFPEEVPFVITRCTAEIEHRALGLQGIYRVSGSRVRVERLCQAFENGRALVELSGNS-PHD------ITSVLKRFLQELTDPVVPFHLYDAFISLAKTLHADPGDDPGTPNP--SPEIIRSLKTLLVQLPDSNYSTLRHLVAHLFRVAARFEENKMSANNLGIVFGPTLLRPPDGPRATGASPVACLLDSGHQAQLVEFLIVHYEQIFG------MDELPLASEPLTQDPGLAPACLE-SSPQHPASLLAQDTQPLTIALDSSP-DPKHHSALEKCPEVTPPELATLQRDQREEEVEDTRDGAGDGSSHCPEDLALGAQSRGHFSRQPVKYSRGG-----VRPVTHQLSS-----------------------------LALVASKLCEETPVTVSAVHRGSLRVRGLGPAAACPEGSPLRRNPLPKHFEITQETARLLSKLNSDAVSRTTCCADPE----PEESEEHL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P107-1", "uniprot_id": "GMIP_HUMAN", "id": "Q9P107-1", "name": "GEM-interacting protein", "aln": "-MDAAEPGLPPGPEG---------RKRYSDIFRSLDNLEISLGNVTLEMLAG--DPLLSEDPEPDKTPTATVTN----EASCWSGPSPEGP-----VPLTGEELDLRLIRTKGGVDAALEYAKTWSRYAKELLAWTEKRASYELEFAKSTMKIAEAGKVSIQQQSHMPLQYIYTLFLEHDLSLGTLAMETVAQQKRDYYQPLAAKRTEIEKWRKEFKEQWMKEQKRMNEAVQALRRAQLQYVQRSEDLRARSQGSPEDSAPQASPGPSKQQERRRRSREEAQAKAQEAEALYQACVREANARQQDLEIAKQ-RIVSHVRKLVFQGDEVLRRVTLSLFGLRGAQAERGPRAFAALAECCAPFEPG---QRYQEFVRALRPEAPPPPPPAFSFQEFLPSLNSSPLDIRKKLSGPLPPRLDE-NSAEPGPWEDPGTGWRWQGTPGPTPGSDVDSVGGGSESRSLDSPTSSPGAGTRQLVKASSTGTESSDDFEERDPDLG-DGLENGLGSPFGKWTLSSAAQTHQLRRLRG-PAKCRECEAFMVS-GTECEECFLTCHKRCLETLLILCGHRRLPARTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENGRALVELSGNS-PHD------VSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSP--SPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPPDGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIFG------MDELPQATEPPPQDSSPAPGPLT-TSSQPPPPHLDPDSQPPVLASDPGP-DPQHHSTLEQHPTATPTEIPTPQSDQREDVAEDTKDGGGEVSSQGPEDSLLGTQSRGHFSRQPVKYPRGG-----VRPVTHQLSS-----------------------------LALVASKLCEETPITS--VPRGSLRGRGPSPAAASPEGSPLRRTPLPKHFEITQETARLLSKLDSEAVPRATCCPDVQ----PEEAEDHL---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UVF1-1", "uniprot_id": "A0A8N7UVF1_DANRE", "id": "A0A8N7UVF1-1", "name": "", "aln": "MEETVETAQLRQPKDGDIPVRHSETKRYSEILRDFDALDLSLKCSTVDELLQEADSLSLPDTSADTTLNADLDDITGEDVEDEVKICREEEEKDEGTLSIAQDADLSLCHCEDGVELALQYAKMWCRYAKDLLTWMDKRISLEQEFAKSIMRAADAAKSCVAQQDMMPLQNIYTQALEHDLKTSASAKQSAENIQQRCYQALSAKRNEIDKWRREFKEQWSKEQKRMHDAVSALKRARQQYMQRCEELEKAKAMTAK---AEEDTGGYKTLDKRRKSRDDAQTKVTETEMQYRQCVSEANNHQKELDKVKR-KIIVHIRKLICQGDTVLKEATMKMFNFQRQQTEPVPLAYQNLQLTCAPCEPG---EPYLHYILGKR--LPDQPPQIYIFQEFIPQNRRSPPTGRRKQS-----NIQQDLYALPDDLKHSSSLVDGRRPG----QSDRDSTG------SLES-LSSPAHGTRKLPKASSTGTMSSDDLDEKDPEESEEGLSDSNGMTCKPRSASRAALTHRLRKMKSKMVKCKQCDNYILVNGIECEECGLAVHRKCLEVCQLECEHR----RGFVFGTEFSSLPRETQDSVPFVVLRCTEEIENRALGVQGVYRISGSKPRVLKLCQAFEIQKDQVDLSDLS-PHD------ITSVLKHFFKELPEPLLTFDLYNDFIAVGKEIQRLSEKDHAAESPGIVENIVRRLRELIGRLPVCNNITVQHMMAHLNRVAEQFEDNKMSPGNLGIVFGPTLLR----PLVSGDVSMIALLETSYQALLVEFMISNYDQVFGSATRSGTPPPPPPTAPLPETPPRATCPVSPSSSSSQDPTATSRERPRSLENRTIKRDSSEGYISDKSSSNEAMDQLSPEANERAVLAMSATASPQGLPGQAAEN-QLQTRSRTHLSRQPVKYYRQGSAGAQSRKTSAQLRDENISVSGEGLVSGSADSSRSSSPEPLKTLLCLQETVVPQDKTESQTGAHAGVQRTVSQESVQAG-ASSFVREGNTNQSNNTLRGRERLIRSLRRRSVEEKTSQKVLSGLRLNSGKGEQLHFV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38339-1", "uniprot_id": "RGD1_YEAST", "id": "P38339-1", "name": "RHO GTPase-activating protein RGD1", "aln": "---MEETAKKPASAT---------VSAKSSHDGGTDDLAHLFSTPEIKKVLN----------------------------------------------------------SDVAINALLSRLKQSLLTCEEFMKFIRKKYAFEEEHVQELSKQYKHFFN-IQGSTNSSLKKMIHEVLGFDGKMAQVKQSYITALQK-MYSEISSLLLTMTKLRKSVKENSKRLEKDVSDAIHSAEKAQSRYNSLCQDWDKLRMTDPT-----KTKLTLRGSKTTKEQEEELLRKIDNADLEYKQKVDHSNSLRNTFITKERPRIVQELKDLILEIDTAMTIQLQKYTIWTENLVLNTGVTISPLDSTKSMKSFAGSVSNERDLYSFLNKYNQTGKHSLLINKNLIPVSYKKHPSMNHGQKNKSPPKFAVDPSRNSIPKRMISTHNESPFLS-----------------------SSSNTAAVPNANLNSATPSLNTNKQLPPTMASSISSTSNAAGAMSPSSSIVTSDTTSSITKTLDPGNNSPQIPEELIN--------SLDSDRPISHIQTNNNMPPGVQKNFKTFGVPLESLIEFEQDMVPAIVRQCIYVIDKFGLDQEGIYRKSANVLDVSKLKEEIDKDPANISMILPSKPHSDSDIYLVGSLLKTFFASLPDSVLPKALSSEIKVCLQIEDPTTRKN--------------FMHGLIYNLPDAQYWTLRALVFHLKRVLAHEAQNRMNLRALCIIWGPTIAP----------ANPDDANDVNFQIMAMEVLLEVSDQAFEPE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. . . *. . * * : .. : . .:: *. * .:::: : *: * *..:. : . : . .*: : * .* . . . :: *. ::: : * *:..**: : :* : :* : .::. :* . :: . : . :...:: * ::: *: * .:* :: : :: :*: .::.*: : * .: . : * . . . . . ::: . .: . .: . . . ** .. . *:* : .::. . .. .:. * : : * : : . :. : :: * .: . . **. : .* . : ** :: :* *:: .*. :*:** *.. * :* : :: :.: * **. : *:** *: .*.:.::. : . : : . . .: :: *: .** .: *:: :: ** ** : :*:*. * *::***: : ..* :*.:: :* * ", "identical_positions": 76, "similar_positions": 205, "identity": "7.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-825", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P40890-1", "uniprot_id": "VTH2_YEAST", "id": "P40890-1", "name": "VPS10 homolog 2", "aln": "MALFRALYIIWVFLLIPLSNAEEFTPKVTRTLSRYVFDIVNFDDSNTLIRAEEDSVEISFDAGENWKTIDEIEEPIESFVVDPFRGHDRAFAFVKTAPKFYVTDDQGKSWRPLTIPIS-EKASNYFCDVTTHPIKKKHLIIRCDLLTIKNSG------------------LMYVGREIYTTNDG-VSFSQVKPSFGKIDG-HISTARCDFIKSSEDSDLGGNDASILCLFRNTEYIESTG-STIDKSELILSADGGETFKELVQFKDKVVSRYEILKHHVIVLTQDDMYNEMSSTNIWISNDVSTFQVARTPTKIRHVNMGQIHEDSIGRIVLPVSRERDDEDSNQPGAAEVLISDSEGLKFLPINWIPNNQFGYINVAYPGFLKGTFFGSFHPFIEYSDRKRKYSRQKVREETKVSVDNGLT---WTNLKVVDRENVDLFGCDVTKPERCSLQTHFYDLRNLNPSAGIMMISGIVGDGSAYNWKEEKTFISRDSGLTWRLVHNSTGLYTTGDLGNIIMYIP--YRSNENGDVPSKFYYSLDQGKTWGEYDL---IMPIYPYRLVSTISDGSGSKFILTG-TSITEDPIF--------ITYSIDFSAVFDYKSCEEGDFEDWNLADGKCVNGAKYKYRRRKQDAQCLVKKAFKDLS--LDETPCNSCTGSDYECSFEFVRDAKGDCIPDYNLIALSDICDK-SKGKSVLVKPLQLIKGDKCKTPMKIESVDIPCDEIPKEGSS------DKEIVTTENKFDFEIKFYQYFDTVADESLVMLNSIGDAYISHDGGQTIKRFDTDGEKIVEIVFNPYFNSSAYLFGSKGNIFLTHDRGYSFMIAKLPEARQLGMPLDFSAKAQDTFIYYGGKNCESILSPECHAVAYLTKDGGETFTEMLDNAIHCEFAGTLFKYPSNDDMVMCQVKEKFSQTRSLVSSTDFFQDDRKTVFENIIGYLSTGGYIIVAVPHEDNELRAYVTNDGAEFTEAKFPYDEDIGKQDAFTILGSEEGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKVQGLEGIIITNIVSNSEKVGENKEDEQLKTKITFNDGSDWNFLKPPKKDSEGKKFPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGDRLLPYEECSTFLTTDGGETWTEVKKGPHQWEYGDHGGVLVLVPENAETDSISYSTDFGKTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGRKRADFKYSPLGSRTGCLFGHKTEFLRKTDEKCFIGNIPLSEFSRNVKNCPCTRQDFECDYNFYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYRKIPLSTCKGGLKLDAHLAPHP--CPGKEKAFREKYSINTGAYALVFVTILLVIFFVAWFVYDRGIRRNGGFSRFEEIRLGDDGLIENNRTDRVVNIIVRLG--------LCISLITKSAFQRAKAGTAQLSSKFRARFGNKKGATYSSLLHDQLSDEPD----GFHEDSNDLSSFRGQGSNSEIEQEDVDTSQQEHTSRTDLLGASNIPDALPARS--ASHESDLAAARSEDK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40438-1", "uniprot_id": "VTH1_YEAST", "id": "P40438-1", "name": "VPS10 homolog 1", "aln": "MALFRALYIIWVFLLIPLSNAEEFTPKVTRTLSRYVFDIVNFDDSNTLIRAEEDSVEISFDAGENWKTIDEIEEPIESFVVDPFRGHDRAFAFVKTAPKFYVTDDQGKSWRPLTIPIS-EKASNYFCDVTTHPIKKKHLIIRCDLLTIKNSG------------------LMYVGREIYTTNDG-VSFSQVKPSFGKIDG-HISTARCDFIKSSEDSDLGGNDASILCLFRNTEYIESTG-STIDKSELILSADGGETFKELVQFKDKVVSRYEILKHHVIVLTQDDMYNEMSSTNIWISNDVSTFQVARTPTKIRHVNMGQIHEDSIGRIVLPVSRERDDEDSNQPGAAEVLISDSEGLKFLPINWIPNNQFGYINVAYPGFLKGTFFGSFHPFIEYSDRKRKYSRQKVREETKVSVDNGLT---WTNLKVVDRENVDLFGCDVTKPERCSLQTHFYDLRNLNPSAGIMMISGIVGDGSAYNWKEEKTFISRDSGLTWRLVHNSTGLYTTGDLGNIIMYIP--YRSNENGDVPSKFYYSLDQGKTWGEYDL---IMPIYPYRLVSTISDGSGSKFILTG-TSITEDPIF--------ITYSIDFSAVFDYKSCEEGDFEDWNLADGKCVNGAKYKYRRRKQDAQCLVKKAFKDLS--LDETPCNSCTGSDYECSFEFVRDAKGDCIPDYNLIALSDICDK-SKGKSVLVKPLQLIKGDKCKTPMKIESVDIPCDEIPKEGSS------DKEIVTTENKFDFEIKFYQYFDTVADESLVMLNSIGDAYISHDGGQTIKRFDTDGEKIVEIVFNPYFNSSAYLFGSKGNIFLTHDRGYSFMIAKLPEARQLGMPLDFSAKAQDTFIYYGGKNCESILSPECHAVAYLTKDGGETFTEMLDNAIHCEFAGTLFKYPSNDDMVMCQVKEKFSQTRSLVSSTDFFQDDRKTVFENIIGYLSTGGYIIVAVPHEDNELRAYVTNDGAEFTEAKFPYDEDIGKQDAFTILGSEEGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKVQGLEGIIITNIVSNSEKVGENKEDEQLKTKITFNDGSDWNFLKPPKKDSEGKKFPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGDRLLPYEECSTFLTTDGGETWTEVKKGPHQWEYGDHGGVLVLVPENAETDSISYSTDFGKTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGRKRADFKYSPLGSRTGCLFGHKTEFLRKTDEKCFIGNIPLSEFSRNVKNCPCTRQDFECDYNFYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYRKIPLSTCKGGLKLDAHLAPHP--CPGKEKAFREKYSINTGAYALVFVTILLVIFFVAWFVYDRGIRRNGGFSRFEEIRLGDDGLIENNRTDRVVNIIVRLG--------LCISLITKSAFQRAKAGTAQLSSKFRARFGNKKGATYSSLLHDQLSDEPD----GFHEDSNDLSSFRGQGSNSEIEQEDVDTSQQEHTLRTDLLGASNIPDALPARS--ASHESDLAAARSEDK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53751-1", "uniprot_id": "YN94_YEAST", "id": "P53751-1", "name": "Uncharacterized membrane glycoprotein YNR065C", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLMTGSVGDGSEFDWEDQKTFISRDGGLTWRFVHNSSGLYATGDLGNIIVYIP--YDPEEDGDFQSEFYYSLDQGRTWNEYELTNAISSVHPYKLINPTPDGSGSKFIFKG-TFATTDSETNSITSLKGVEYIIDFSAAFDSRTCEEEDFEDWDLADGKCVNGAKYKYRRRKQDAQCLVKKAFKDLS--LDETPCNSCGESDYECSFEFVRDANGLCIPDYNLIAFSNICDK-SKDKSVLVEPLQLIKGDECKTPMKIEPVDIPCDEIPEEGSS------DREIVTTENKFDFEIKFYQYFDTVADESLVMLNSIGDAYISHDGGQTIKRFDTNGEKIVEVVFNPYFNSSAYLFGSKGNIFSTHDRGHSFMIAKLPEARQLGMPLDFSAKAQDTFIYYGGKNCESILSPECHAVAYLTKDGGETFTEMLDNAIHCEFAGTLFEYPSNEEMVMCQVKKKSSETRSLVSSIDFFQGDNKIIFENIIGYLSTGGYIIVAVPHEDNELRAYVTIDGTEFAEAKFPYGQDVSKQEAFTILGSEKGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKVQGLEGIIITNIVSNREKVGENKEDEQLKTKITFNDGSDWNFLKPPKKDSEGKKFPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGDKLLPYEECSTFLTTDGGETWTEVKKGPHQWEYGDHGGVLVLVPENAETDSISYSTDFGKTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGKKRADFKYSPLGSRTGCLFGHQTEFLRKTDEKCFIGNIPLSEFSRNVKNCSCTRQDFECDYNFYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYRKIPLSTCKGGLKLDAHLAPHP--CPGKEKAFREKYSINTGAYALVFVTILLVIFFAAWFVYDRGIRRNGGFSRFEEIRLGDDGLIENNRTDRVVNIIVRLG--------LCISLITKSAFQRTKAGVARFSSKLRARFGNRKGPTYSSLLQGQFSDESD----GLHEDANDLSSFTSQDSNFEIEQEDAYRPEQEHTSQIDQPATSNIPDALPARS--AIHKPDSTAVRNEDE-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32319-1", "uniprot_id": "VPS10_YEAST", "id": "P32319-1", "name": "Vacuolar protein sorting/targeting protein VPS10", "aln": "MILLHFVYSLWALLLIPLTNAEEFTPKVTKTIAQDSFDILSFDDSNTLIRKQDTSVTISFDDGETWEKVEGIEGEITWIYIDPFNRHDRAVATAMNGSYLYITNDQGKSWERITLPDSGESISPRECYIETHPLNKNYFLAKCNYCEKTEVNNDNEENSGDEEGQFEIFNITRCTDKVFASNDGGKSFSEIKSSLERNENSPISISDCGFAKTSKDSDLESSDTSIICLFQNMQLIMDEFSSPYTESKLVLTTDWGKSLKEFDQFKDKVVNGYRILKSHMVVLTQGDRYNDMSSMDVWVSNDLSNFKMAYMPTQLRHSMQGEIYEDAMGRIILPMSRERSDQEEDKGIVSEILISDSQGLKFSPIPWTANEVFGYINFYQPTYLKGTMIASLYPLSRRRNRKGKAKGVKSKGVTKISVDNGLT---WTMLKVVDPDNADSFDCDITDFENCSLQNMFYTREGSTPTAGILMTTGIVGDGSVFDWGDQRTFISRDGGLTWKLAFDFPCLYAVGDYGNVIVAIP--YNADEDDDPQSEFYYSLDQGKTWTEYQL---ETTIYPNEVMNTTPDGSGAKFILNGFTLAHMDGTTN-------FIYAIDFSTAFNDKTCEENDFEDWNLAEGKCVNGVKYKIRRRKQDAQCLVKKVFEDLQ--LFETACDKCTEADYECAFEFVRDATGKCVPDYNLIVLSDVCDK-TKKKTVPVKPLQLVKGDKCKKPMTVKSVDISCEGVPKKGTN------DKEIVVTENKFDFKIQFYQYFDTVTDESLLMINSRGEAYISHDGGQTIKRFDSNGETIIEVVFNPYYNSSAYLFGSKGSIFSTHDRGYSFMTAKLPEARQLGMPLDFNAKAQDTFIYYGGKNCESILSPECHAVAYLTNDGGETFTEMLDNAIHCEFAGSLFKYPSNEDMVMCQVKEKSSQTRSLVSSTDFFQDDKNTVFENIIGYLSTGGYIIVAVPHENNELRAYVTIDGTEFAEAKFPYDEDVGKQEAFTILESEKGSIFLHLATNLVPGRDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKIQGLEGIILTNIVSNSDKVAENKEDKQLKTKITFNEGSDWNFLKPPKRDSEGKKFSCSSKSLDECSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGPNLLPYKECSTFFTTDGGETWAEVKKTPHQWEYGDHGGILVLVPENSETDSISYSTDFGKTWKDYKFCADKVLVKDITTVPRDSALRFLLFGEAADIGGSSFRTYTIDFRNIFERQCDFDITGKESADYKYSPLGSKSNCLFGHQTEFLRKTDENCFIGNIPLSEFSRNIKNCSCTRQDFECDYNFYKANDGTCKLVKGLSPANAADVCKKEPDLIEYFESSGYRKIPLSTCEGGLKLDAPSSPHA--CPGKEKEFKEKYSVSAGPFAFIFISILLIIFFAAWFVYDRGIRRNGGFARFGEIRLGDDGLIENNNTDRVVNNIVKSG--------FYVFSNIGSLLQHTKTNIAHAISKIRGRFGNRTGPSYSSLIHDQFLDEADDLLAGHDEDANDLSSFMDQGSNFEIEEDDVPTLEEEHTSYTDQPTTTDVPDTLPEGNEENIDRPDSTAPSNENQ-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P25657-1", "uniprot_id": "YCY9_YEAST", "id": "P25657-1", "name": "Uncharacterized protein YCR099C", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRSIFLLHFDYKTCEEEDFEDWNLADGKCLNGAKYMYKRRKQDARCLVKRTFKDMI--LHEIPCDSCTESDYECSSEFVRDAKGDCIPDYDQIALSDICDK-ANGETVSLEPLQLIKGDKCKKPMEIEAMNIPCEKILRESSN------GKKIATIENKFDFEI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "D3ZW09-1", "uniprot_id": "D3ZW09_RAT", "id": "D3ZW09-1", "name": "VPS10 domain-containing receptor SorCS2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHRGTPSAPKRPGLTAPDRSSQVLLPPCWPRSWPLLLLLLVLVAACGAMGRSPQPGRWGPSVQVTRLL---PAGRTESSNRQDPQTRESEPGVPGLRPGSASGPSTDGAPALGKGRRVRAAPVAGAASASRAQVSLISTSFVLKGDATHNQAMVHWTGENSSVILILTKYYHADMGKVLESSLWRSSDFGTTYTKLTLQPGVTTVIDNFYICPANKRK-IILVSSSLGDREQSLFLSTDEGTTFQKYPVPFLVETLLFHPKEEDKVLAYTKDSKLYVSSDLGKKWTLLQEQVTKDHVFWAVSGVDDDPNLVHMEARDLSGGYRYYTCLIHNCSAQPHTAPFPGPTDRGSLTVQDEYIFLKATSTNRTKYYVSYRRSDFVLMKLPKYALPKLFCPQDLQIISTDEQQVFVAVQEWNQVDTYNLYQSDLRGVRYSLVLENVRSSRQAEENVVIDILEVRGVKGVFLANQKVDGKVTTVITYNKGRDWDYLRPPSTDMNGKPTNCQP-------------------PDCHLHLHLRWADNPYVSGTVH--TKDTAPGLIMGAGNLGSQLVEYKEEMYITSDCGHTWRQVFEEEHHVLYLDHGGVIAAIKDTSIPLKTLKFSVDEGHTWSTHNFTSTSVFVDGLLSEPGDETLVMTVFGHISFRSDWELVKVDFR----------PSFPRPCVEDDYSSWDLTDLQGDHCIMGQQRSYRKRKSTSWCVKGRSFTSALTSRVCKCRDSDFLCDYGFERSSSSESTVNKCSANFWFNPLSPPEDCVLGQTYTSSLGYRKVVSNVCEGGVDLQQSPVQLQCPLQAPRGLQVSIRGEAVAVRPREDVLFVVRQEQGDVLTTKYQVDLGDGFKAMYVNLTLTGEPIRHHYESPGIYRVSVRAENMAGHDEAVLFVQVNSPLQALYLEVVPVIGINQEVNLTAVLLPLNPNLTVFYWWIGHSLQPLLSLDNSVTTRFTDAGDVRVTVQAACGNSVLQDSRLVRVLDQFQVVPLQFSRDLDTFNPNTPEWREDVGLVVTRLLSKETSIPEELLVTVVKPGLPTIADLYVLLPPPRPTRKRSLTSDKRLAAVQQALNSHRISFILRGGLRVLVELRDTDAGPQR-----------------------PGGSGGYWAVVVLFVIGLFAVGAFILYKFKRK-------------------------RPGRTVYAQMHNEKEQEMTSPVSHSEDAQSAMQG--------------NHSGVVLSINSREMHSYLVG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPR5-1", "uniprot_id": "SORC2_MOUSE", "id": "Q9EPR5-1", "name": "VPS10 domain-containing receptor SorCS2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHRGPPSAPKRPGPTAPDRSFQALLPPCWPRSWPLLLLLLVLVAACGAMGRSPQPGRQGPGVQITRLL---PAGRTESGDRKDPQARESEPSVPGLGPGSASGPSTDGAPAPGKGRRARAVPVAGAASASRAQVSLISTSFVLKGDATHNQAMVHWTGENSSVILILTKYYHADMGKVLESSLWRSSDFGTTYTKLTLQPGVTTVIDNFYICPANKRK-IILVSSSLGDREQSLFLSTDEGATFQKYPVPFLVEMLLFHPKEEDKVLAYTKDSKLYVSSDLGKKWTLLQERVTKDHVFWAVSGVDDDPNLVHVEAQDLSGGYRYYTCLIYNCSAQPHIAPFSGPIDRGSLTVQDEYIFLKATSTNRTKYYVSYRRSDFVLMKLPKYALP-----KDLQIISTDEQQVFVAVQEWNQVDTYNLYQSDLRGVRYSLVLENVRSSRQAEENVVIDILEVRGVKGVFLANQKVDGKVTTVITYNKGRDWDYLRPPSTDMNGKPTNCQP-------------------PDCYLHLHLRWADNPYVSGTVH--TKDTAPGLIMGAGNLGSQLVEYKEEMYITSDCGHTWRQVFEEEHHVLYLDHGGVIAAIKDTSIPLKILKFSVDEGHTWSTHNFTSTSVFVDGLLSEPGDETLVMTVFGHISFRSDWELVKVDFR----------PSFPRQCGEDDYSSWDLTDLQGDHCIMGQQRSYRKRKSTSWCVKGRSFTSALTSRVCKCRDSDFLCDYGFERSSSSESTANKCSANFWFNPLSPPEDCVLGQTYTSSLGYRKVVSNVCEGGVDLQQSPVQLQCPLQAPRGLQVSIRGEAVAVRPREDVLFVVRQEQGDVLTTKYQVDLGDGFKAMYVNLTLTGEPIRHHYESPGIYRVSVRAENMAGHDEAVLFVQVNSPLQALYLEVVPVIGVNQEVNLTAVLLPLNPNLTVFYWWIGHSLQPLLSLDNSVTTKFTDAGDVRVTVQAACGNSVLQDSRLVRVLDQFQVVPLRFSRELDTFNPNTPEWREDVGLVVTRLLSKETSIPEELLVTVVKPGLPTIADLYVLLPLPRPTRKRSLTSDKRLAAVQQALNSHRISFILRGGLRILVELRDTDTGPQR-----------------------PGGSGGYWAVVVLFVIGLFAVGAFILYKFKRK-------------------------RPGRTVYAQMHNEKEQEMTSPVSHSEDAQSTMQG--------------NHSGVVLSINSREMHSYLVG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PQ0-1", "uniprot_id": "SORC2_HUMAN", "id": "Q96PQ0-1", "name": "VPS10 domain-containing receptor SorCS2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAHRGPSRASKGPGPTARAPSPGAPPPPRSPRSRPLLLLLLLLG-ACGAAGRSPEPGRLGPHAQLTRVPRSPPAGRAEPGGGEDRQARGTEPGAPGPSPGPAPGPGEDGAPAAGYRRWERAAPLAGVAS--RAQVSLISTSFVLKGDATHNQAMVHWTGENSSVILILTKYYHADMGKVLESSLWRSSDFGTSYTKLTLQPGVTTVIDNFYICPTNKRK-VILVSSSLSDRDQSLFLSADEGATFQKQPIPFFVETLIFHPKEEDKVLAYTKESKLYVSSDLGKKWTLLQERVTKDHVFWSVSGVDADPDLVHVEAQDLGGDFRYVTCAIHNCSEKMLTAPFAGPIDHGSLTVQDDYIFFKATSANQTKYYVSYRRNEFVLMKLPKYALP-----KDLQIISTDESQVFVAVQEWYQMDTYNLYQSDPRGVRYALVLQDVRSSRQAEESVLIDILEVRGVKGVFLANQKIDGKVMTLITYNKGRDWDYLRPPSMDMNGKPTNCKP-------------------PDCHLHLHLRWADNPYVSGTVH--TKDTAPGLIMGAGNLGSQLVEYKEEMYITSDCGHTWRQVFEEEHHILYLDHGGVIVAIKDTSIPLKILKFSVDEGLTWSTHNFTSTSVFVDGLLSEPGDETLVMTVFGHISFRSDWELVKVDFR----------PSFSRQCGEEDYSSWELSNLQGDRCIMGQQRSFRKRKSTSWCIKGRSFTSALTSRVCECRDSDFLCDYGFERSSSSESSTNKCSANFWFNPLSPPDDCALGQTYTSSLGYRKVVSNVCEGGVDMQQSQVQLQCPLTPPRGLQVSIQGEAVAVRPGEDVLFVVRQEQGDVLTTKYQVDLGDGFKAMYVNLTLTGEPIRHRYESPGIYRVSVRAENTAGHDEAVLFVQVNSPLQALYLEVVPVIGLNQEVNLTAVLLPLNPNLTVFYWWIGHSLQPLLSLDNSVTTRFSDTGDVRVTVQAACGNSVLQDSRVLRVLDQFQVMPLQFSKELDAYNPNTPEWREDVGLVVTRLLSKETSVPQELLVTVVKPGLPTLADLYVLLPPPRPTRKRSLSSDKRLAAIQQVLNAQKISFLLRGGVRVLVALRDTGTGAEQ-----------------------LGGGGGYWAVVVLFVIGLFAAGAFILYKFKRK-------------------------RPGRTVYAQMHNEKEQEMTSPVSHSEDVQGAVQG--------------NHSGVVLSINSREMHSYLVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G5D7-1", "uniprot_id": "A0AC58G5D7_DANRE", "id": "A0AC58G5D7-1", "name": "VPS10 domain-containing receptor SorCS2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKTLIMAVFAHLYPAVFFACAWMALLGPISCHSSGIIKQRSERDR-------------------ELDSRGGHVTGTDEALISAYSRGDYSG--DPGGAAVGVPRVRRAS--------TPEKVSLLSSSFVLKGDATHNQAMVHWTGENSSVILILTKYYHADSNKVLESSLWRSSDYGSTYTKLNLMPGTTIIVTNFYICPTNKKK-VILVSSSINERDQMLFISTDEGASFQRQPVSFTVDSLLFHPSEEDKLLAYSKEAKLYISTDLGHKWTLLQERVTKDRVFWAVTGVDVDPDLVHMEMQDISGGYLYVTCLIQNCSDKMVTAQFLGKIDHNSLSVQDEYIFVKVTTGNRTKYYVSYRRNEFVQMRFPKYSLP-----KDVQIVSTDENQVFLALQEWYQTDTYNLYQSDPQGVYYSIVLENVRSTKQPEENVLIDILEVRGVKGVFLANQKVDGKVMTLITYNKGRDWEALAPPATDMNGKPVSCKQ-------------------PDCHLHLHLRWADNPYVSGTVH--TKDSAPGLIMGAGNLGSQLVEYKEEMYITADCGKTWRQVFEEEHHILYLDHGGVIVAIKDTSIPLKILKFSIDEGRTWSIHNFTSTSVFVDGLLSEPGDETLVMTVFGHISYRSDWELVKVDFR----------QSFPRQCTEADYDSWKLTDLQGEKCIMGQERVYRRRKETSFCIKGKSYTSALTAKPCPCSEKDFTCDYGFERAPSLRLEGDRCYPDFWHNPDAPPENCHLGHSYKSSTGYRKVIANVCEGGLNKEQSAKQHSCPLLPPKGLQLGIKGQMLAVAPGDDITFIVHQEQGDTSSTRYQVDLMDGVRAIYENLTVTDEPIQHRYEKPGVYRVNVKAENSAGHDQAMLYIQVTAPLQDVHLEVVPIAGRNQDVNLTAIVLPTEANLTVFYWWIGDNMQPKLTLENSLITRFSEEGEVPVTVQASNGRSMVQDSKTVIVYDHFQIIPLSFSRNLDHFNPNIPEWRRDVGEVVTKIIAKLTGVPQEHLVTMLKPGLPTSADLYVLPQETTP-VKRSVFVDKRVPTIKQVLSENNVSFIVRGGLRVLVTLADLDSGPITSDVSVSTTETATQLTSSTQGSGLAAAGPGVWAVAVFLLISLISAAAFILFKFKRKNYKNHGWLLRPEESSLTRPWLRFRKLPGRNVYAQMHNEKEQEMTSPVNHSEDTQNIIQGEEFIDDDLDSQTLGNHSGVVLSINSRELHSYLTS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .* * :.* . . : : : .:.* : : * : * . : . *: : .: . :. * : . :: . . . . :* ::. * ", "identical_positions": 11, "similar_positions": 36, "identity": "0.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-826", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BQ83-1", "uniprot_id": "SLX1_HUMAN", "id": "Q9BQ83-1", "name": "Structure-specific endonuclease subunit SLX1", "aln": "MGPAGVAARPGRFFGVYLLYCLNPRYRGRVYVGFTVNTARRVQQHNGGRKKGGAWRTSGRGPWEMVLVVHGFPSSVAALRFEWAWQHPHASRRLAHVGPRLRGETAFAFHLRVLAHMLRAPPWARLPLTLRWVRPDLRQDLC--LPPPPHVPLAFGPPPPQAPAPRRRAGPFDDAEPEPDQGDPGACCSLCAQTIQDEEGPLCCPHPGCLLRAHVICLAEEFLQEEPGQLLPLEGQCPCCEKSLLWGDLIWLCQMDTEKEVEDSELEEAHWTDLLET", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BX32-1", "uniprot_id": "SLX1_MOUSE", "id": "Q8BX32-1", "name": "Structure-specific endonuclease subunit SLX1", "aln": "---MDHAARPGRFFGVYLLYCQNPRHRGRVYVGFTVNPARRVRQHNAGRKKGGAWRTSGRGPWDMVLIIHGFPSAVAALRFEWAWQHPQASRRLTHVGPRLRSEAAFAFHLRVLAHMLRVPPWVRLPLTLRWLRPDFRHELC--PAPPAHMPIAFGPPPPQPLVPKRPAVSEADSERQLDLG-TKARCSLCARLLQDEEGPLCCPHPGCPLRAHIICLAEEFLQEEPGQLLPLEGHCPSCKKSLLWGNLVGQCHADTEEE-EDLELEEEHWTDLLET", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IAZ1-1", "uniprot_id": "A0A0R4IAZ1_DANRE", "id": "A0A0R4IAZ1-1", "name": "", "aln": "-----MVVEVESFYGVYMLYCTNPKFKGRIYIGFTVNPERRIGQHNAGRHRGGAKRTSGRGPWEMVLIIHGFPSDIAALRFEWAWQHPHISRRLSHVSRRSRKESGLQFHWRVVSNMLRVAPWSRLPITVRWLKQEYRMDFAPDLQPPLHIPLTFGCVRAK---RKPQHVSKEQEERQ------VELCVLCGEFIKTVDR-LSCFHPSCQMVCHLICLAGHFLKADPFHLIPVEGKCPGCHHSVLWGSLILYKNADLEEM--NIPSSQNHWTDELQL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... *:***:*** **:.:**:*:*****. **: ***.**::*** ********:***::***** :************: ****:**. * * *:.: ** **:::***..** ***:*:**:: : * ::. ** *:*::** .: : . : * : * **.. :: : *.* **.* : .*:**** .**: :* :*:*:**:** *.:*:***.*: : * *: : .: **** *: ", "identical_positions": 122, "similar_positions": 75, "identity": "44.04%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-832", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZN85-1", "uniprot_id": "A0A8I5ZN85_RAT", "id": "A0A8I5ZN85-1", "name": "Jumonji domain-containing protein 1C", "aln": "MAVETRPELVGKRFLCVAAGEDARPERGQSGCG-RGWRAGVIRAVSHRDRGHPDLAVYVEFDDLEWDKREWVKVYEDFSTFLVEYHLIWAKRKDPSQTQGSKSRQ---IQWPALTFKPLVENSIPSSVTAVEFLIDKQVDFLTEESAFQLYQDDIDSLKPELRDNPQLHAEVKVWVKEQKVQEIFMQGPYSLNGYRVRVYRQDSATQWFTGIITHHDLFTRTMIVMNDQVLEPQNVDPSMVQMTFLDDVVHSLLKGENIGITSRRRSRASQNISTVHGHYTRAQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPSKRKGSDSSAPDEERMKGDKYDYGSRGENPKGKNKHMVTKRRKPEEDEKRLTMKRLRTDNASDASESSDSENSSKRITENSS-EQTPEYELKNKITSK-------INGEDGQPQAAEKAGEEILIDTRPHWDQMQEDKN--HEEGEKLKSMDSHLQDKITLRASEQATDADPNSNDSVLQECNMENQRTVELPSKDRVVSRTPTPKCAMDIKNDTHSERAAQEKSNTFGLQIPENMDSNVSDSKH--SNAKYLEAAKKDCDQSWVSDVVKVDLTQSSTTNTPSGNDNREMEKERNHYVSYMSSLSTVSVTEDQLHKRSPPPETIRSKLTTSVDTQKTKS-----------SSSPEVFKPKVTHSPDSVKSRAAYGNSQAAGERRQASKAEHELSRGSFHAAPTRGSALET-TKSPLIIDKNEHFTVYRDPALIGSEAGANHISPFLSQHPFPLHSSSHRTCLNPGSHHPALTPGP---HLLAGSSSQTPLPTINTHP------LTSGPHHPVHHPHLLPTVLPGV-PTASLLGGHPRLESAHTGSLSHLALAHQQQQ-LLQHQSPHLLGQAHPSASYNQLGLYPIIWQ-YPNGTHAYSGLGLPSSKWVHPENAVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPPRPHKMTVHSSPPLTKTLADHHKEELERKAFMEPLRSNASTSVKGDLDLNRSQAGKDCHLHRHFVGP------RLPPE----TGERLNKYKEEHRRILQESIDVAPFTTKIKGHEVERENYSRVVPSSSSPKSHAIKPDKDMDRS-VSELYKMKHSVS---------QSLPQSNYFTTLSNSVLNEPPRSYPSKEVSSIHTEKQNSNLSAAAN-PQTLS-FISSLSKPPPLIKHQPE-SESLVGKVPDHLPHQSAS-HSVTTFRSDCRSPTHLTVCSTNALRSMPALHRAPVFHPPIHHSLERKESSYSSLSPPTLTPVMPVNAGGKAQESQKPPTLIPEPKDSQADLK--------SSDQSLVEVWRSNN-LSKEKAEWPVEKNSGKSQAAVASVIVRPPSSTKVDSVPSGPLAAKDRVCERASSGANKTDYLKP-EAGETGRILLPNVNLESAHVKSEKNFEAASQGSVPVSVMSAVNVVSATQ--TDVLTSAGPTTSVSSLAGSEATYSLSNIISASTPLECPSSKS-VSQSVAQAKGCKVSTPVPVTLACSKTANAVQPGSGFSGTTDFIHLKK----HKAALAAAQYKNSNVSEAELNTVRNQTAAASLPLDSTMTCAASN--------KAVSVGNGPAAQPSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGTCVSEMIKPCSVNLIAS--------TSSDIQNSVDGR----------------------------------------------------------------VTVDKYGRDEKAS----------RRKAKRTYESGSESADSDGSESKAE-----QRTKRQPKPTYKKKQNDLQKRKGEIEED---LKPNGVLSRSAKEKSKLKLQNSSSAGVPRSVLKDWRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRLI--RSKKGEESTHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPD-QYDDEAMSLWTHENYEDD-----DIDVETSKYILDIIGDKFCQLVTSEKTALSWVK-KDAKIAWKRAVRGVREMCDACEATLFNVHWVCRKCGFVACLDCYKAK---------ERKSSRDKELYAWMKCVKG---QPHDHKHLMPTQIIPGSVLTDLLDAMHVLREKYGIKSHCHCANRQNLQGGNVPTMNGVSQVLQNALHHSNKTSACPPESQQQSTPQRAQANGSSSPGS-ASTDSRLTPPESQSPLHWLADLAEQKSREEKQENKEFTLEKEIKEDEEQDTPDSPNGSTSPPASQNSEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGASSGKGGRTMPNILDDIIASVVENKIPPNKTSKINVKSEPNEEPKESRQS---ATNESNKF--YRDIPHTWICDQHVLWLKDYKNSNNWKLFKECWKQGQPAVVSGVHKKMNVSLWKAESISLDFGDHQADLLNCKDS-IVSNANVKEFWDGFEEVSKRQKNKGGETVVLKLKDCPSGEDFKTMMPARYEDFLRSLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSAYGVAAAKDHDIGTTNLHIEASDVVNVLVYVGIAK-GNGVLSKAGILKKFEEEELDDILRKRLKDSSEIPGALWHIYAGKDVDKIREFLQKVSKEQGLEVLPEHD----------PVRDQGWYVNRRLRQRLLEEYGVRACTLVQFLGDAIVLPAGTLHQVQNFHSCIQVTEDFVSPEHLVQSFHLTQELR-LLKEEINYDDKLQVKNILYHAVKEMVRALKMHEDEVEDMEDT-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q69ZK6-1", "uniprot_id": "JHD2C_MOUSE", "id": "Q69ZK6-1", "name": "Jumonji domain-containing protein 1C", "aln": "MAVETRPELVGKRFLCVAAGEDARPERGQSGCG-RGWRAGVIRAVSHRDRGHPDLAVYVEFDDLEWDKREWVRVYEDFSTFLVEYHLIWAKRKDPSQTQGSKSRQ---IQWPALTFKPLVENSIPSSITAVEFLIDKQLDFLTEDSAFQPYQDDIDSLKPVLRDNPQLHAEVKVWVKEQKVQEIFMQGPYSLNGYRVRVYRQDSATQWFTGIITHHDLFTRTMIVMNDQVLEPQNVDPSMVQMTFLDDVVHSLLKGENIGITSRRRSRASQNISTVHGHYTRAQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEDKYDCVSRGENPKGKNKHVVTKRRKPEEAEKRLSMKRLRTDNASDASESSDAESSSKRVTETSSSEPMPEYEPKNKVTSK-------VNGEEGQSQAAEEAGEETLIDTRPPWDQMQEDKN--HNEGEKPKSTDSHLQDKMTLRSSEQATVADHNSNDSVLQECNVENQRTVELLPKDRLVSRTPTPKCVTDIKNDTHSERAAQENLNTFGLQTPENMDPNVSDSKH--SNAKYLETAKQDCDQSWVSDVVKVDLTQSSVTNAPSGSDKRDTEKERNHYVSYMSSLSAVSVTEDQLHKRSPPPETIKAKLTTSVDTQKAKS-----------SSSPEVVKPKITHSPDSVKSKAAYGNSQAVGERRLANKIEHELSRGSFHPVPTRGSALET-TKSPLIIDKNEHFTVYRDPALIGSETGANHISPFLSQHPFSLHSSSHRTCLNPGTHHPALTPGP---HLLAGSTSQTPLPTINTHP------LTSGPHHPVHHPHLLPTVLPGV-PTASLLGGHPRLESAHASSLSHLALAHQQQQQLLQHQSPHLLGQAHPSASYNQLGLYPIIWQ-YPNGTHAYSGLGLPSSKWVHPENAVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPHKITVHSSPPLTKTLADHHKEELERKAFMEPLRSNASTSVKGDLDLNRSQAGKDCHLHRHFVGP------RPPQE----TGERLNKYKEEHRRILQESIDVAPFTTKIKGHEVERENYSRVVPSSSSPKSHAIKQDKDVDRS-VSEIYKMKHSVP---------QSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYTEKQNNNLSATAN-PQTHS-FISSLSKPPPLIKHQPE-SESLVGKIPDHLPHQSAS-HSVTTFRSDCRSPTHLTVSSTNALRSMPALHRAPVFHPPIHHSLERKESSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDSQSNFKN-------SSDQSLTEMWRSNNNLNREKAEWPVEKSSGKSQAAVASVIVRPPSSTKVDSVPSVPLASKDRVCERSSSGANKTDYLKP-EAGETGRIILPNVNLESAHVKSEKNFEAVSQGNVPVSVMSAVNVVSTTK--ADVFTSAATTTSVSSLSSAETSYSLSNTISASTPFECTSSKSVVSQAVAQAKDCTVSTAVPGTLACSKTGSAVQPGSGFSGTTDFIHLKK----HKAALAAAQFKNSSVSEAELNTVRNQTVAASLPLDSTMTCTASN--------KAISVGNGPAAQSSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIAS--------TSNDIENRADGR----------------------------------------------------------------VAVDKYGRDEKVS----------RRKAKRTYESGSESGDSDESESKSE-----QRTKRQPKPTYKKKQNDLQKRKGEVEED---SKPNGVLSRSAKDKSKLKLQNSNSAGVPRSVLKDWRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRLI--RSKKGEESTHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPD-QYDDEAMSLWTHENYEDD-----EVDVETSKYILDIIGDKFCQLVTSEKTALSWVK-KDAKIAWKRAVRGVREMCDACEATLFNVHWVCRKCGFVACLDCYKAK---------ERKSSRDKELYAWMKCVKG---QPHDHKHLMLTQIIPGSVLTDLLDAMHILREKYGIKSHCHCTNRQNLQGGNVPTMNGVSQVLQNVLHHSNKTSVSLPESQQQNSPQKSQTNGNSSPGS-ASTDSRLTPPESQSPLHWLADLAEQKSREEKQENKEFTLEREIKEDGDQDASDSPNGSTSPPASQSNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGTSSGKGGRTMPNILDDIIASVVENKIPPNKTSKINIKSEPNEEPKESSLP---ATDESNKS--YRDIPHSWICDQHILWLKDYKNSNNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQADLLNCKDS-IVSNANVKEFWDGFEEVSKRQKNKGGETVVLKLKDCPSGEDFKAMMPTRYEDFLRCLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSAYGVAAAKDHDIGTTNLHIEASDVVNVLVYVGIAK-GNGVLSKAGILKKFEEEELDDVLRKRLKDSSEIPGALWHIYAGKDVDKIREFLQKISKEQGLEVLPEHD----------PIRDQSWYVNRKLRQRLLEEYGVRACTLIQFLGDAIVLPAGTLHQVQNFHSCVQVTEDFVSPEHLVQSFHLTQELR-LLKEEINYDDKLQVKNILYHAVKEMVRALKMHEDEVEDMEDT-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15652-1", "uniprot_id": "JHD2C_HUMAN", "id": "Q15652-1", "name": "Jumonji domain-containing protein 1C", "aln": "MAVETRAELVGKRFLCVAVGDEARSERWESGRGWRSWRAGVIRAVSHRDSRNPDLAVYVEFDDLEWDKREWVKVYEDFSTFLVEYHLIWAKRNDPSQTQGSKSKQ---IQWPALTFKPLVERNIPSSVTAVEFLVDKQLDFLTEDSAFQPYQDDIDSLNPVLRDNPQLHEEVKVWVKEQKVQEIFMQGPYSLNGYRVRVYRQDSATQWFTGIITHHDLFTRTMIVMNDQVLEPQNVDPSMVQMTFLDDVVHSLLKGENIGITSRRRSRANQNVNAVHSHYTRAQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHLMNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSS-EQKPENELKNKNTSK-------INGEEGKPHNNEKAGEETLKNSQPPWDQIQEDKK--HEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLEKVAQENSSTFGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSVTNASSGNDHLNMEKEK--YVSYISPLSAVSVMEDKLHKRSPPPETIKSKLNTSVDTHKIKS-----------SPSPEVVKPKITHSPDSVKSKATYVNSQATGERRLANKIEHELSRCSFHPIPTRSSTLET-TKSPLIIDKNEHFTVYRDPALIGSETGANHISPFLSQHPFPLHSSSHRTCLNPGTHHPALTPAP---HLLAGSSSQTPLPTINTHP------LTSGPHHAVHHPHLLPTVLPGV-PTASLLGGHPRLESAHASSLSHLALAHQQQQQLLQHQSPHLLGQAHPSASYNQLGLYPIIWQ-YPNGTHAYSGLGLPSSKWVHPENAVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPLKITAHSSPPLTKTLVDHHKEELERKAFMEPLRSVASTSAKNDLDLNRSQTGKDCHLHRHFVDPVLNQLQRPPQE----TGERLNKYKEEHRRILQESIDVAPFTTKIKGLEGERENYSRVASSSSSPKSHIIKQDMDVERS-VSDLYKMKHSVP---------QSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQPE-SEGLVGKIPEHLPHQIAS-HSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPIHHSLERKEGSYSSLSPPTLTPVMPVNAGGKVQESQKPPTLIPEPKDSQANFKS-------SSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRVSERSSAGAHKTDCLKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTK--TDVITSAADTTSVSSWGGSEVISSLSNTILASTSSECVSSKS-VSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKK----HKAALAAAQYKSSNASETEPNAIKNQTLSASLPLDSTVICSTIN--------KANSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIAS--------TSSDIQNSVDSK----------------------------------------------------------------IIVDKYVKDDKVN----------RRKAKRTYESGSESGDSDESESKSE-----QRTKRQPKPTYKKKQNDLQKRKGEIEED---LKPNGVLSRSAKERSKLKLQSNSNTGIPRSVLKDWRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRLI--RSKKGEEPAHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPD-QYDDEAMSLWTHENFEDD-----ELDIETSKYILDIIGDKFCQLVTSEKTALSWVK-KDAKIAWKRAVRGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAK---------ERKSSRDKELYAWMKCVKG---QPHDHKHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMNGVSQVLQNVLNHSNKISLCMPESQQQNTPPKSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQKAREEKKENKELTLENQIKEEREQDNSESPNGRTSPLVSQNNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGAPSSKSGRTMPNILDDIIASVVENKIPPSKTSKINVKPELKEEPEESIIS---AVDENNKL--YSDIPHSWICEKHILWLKDYKNSSNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQADLLNCKDS-IISNANVKEFWDGFEEVSKRQKNKSGETVVLKLKDWPSGEDFKTMMPARYEDLLKSLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSAYGVVAAKDHDIGTTNLHIEVSDVVNILVYVGIAK-GNGILSKAGILKKFEEEDLDDILRKRLKDSSEIPGALWHIYAGKDVDKIREFLQKISKEQGLEVLPEHD----------PIRDQSWYVNKKLRQRLLEEYGVRTCTLIQFLGDAIVLPAGALHQVQNFHSCIQVTEDFVSPEHLVESFHLTQELR-LLKEEINYDDKLQVKNILYHAVKEMVRALKIHEDEVEDMEEN-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PPN0-1", "uniprot_id": "A0A8M9PPN0_DANRE", "id": "A0A8M9PPN0-1", "name": "", "aln": "----MAVELPGKRCLCASGSGDRLLEP--AGISHWGWRAGVIRAAAAD---CPALTVCVQWDGEQCAERKWRRLREECEVVLLEQELVWAAKKPSSNGSSNISVQEKRRLQPALKFRPLIGQSCVGGLSVVEFMCDRQLEFYTEKEELQPFKDEVDGGNPAVKDDPPLQEQVQAWLKQNQFQKTLQQGGCSVKGRRVKVFRQESKTQWLSGVITHYEQNNRTVAVMTDQGQEIVSIDPSLVQMLLLDEITQSSMTGD----NSKRKSHITKINRVCLGTGSKTNTTTNDQVCKPVQHQSEISTHNCSMEKDEKEGMR---------EEKRSDEGKDS-SKSKNSHCERKRKKEDEEKDDQQRNRCGLKRLKGGSVSDLSENSDSENSSCRVPDSSS-DLGSKRQLKQRYTSKRPLDCEVHPSHRGGKLSSSQLGETEILGKTPPSDSCSSSCNGAFRNTEAFECAAAVCVGKSDEKGNGGMTEIEDRSEGTSREDSEAVSALLASQES-EQLVSMETT--CVLLHASPLECERAEGEMS-TNDSQVKGSEFTHAEARGTEFNQSEVRRSDFPHSEAITTSNDTPVALEEEPRGEPPCCPVKPCNKKEDGDYKRSQS-PATVNTEYGSESPCCSPETITKPQIIREVSRQKLKEGMAEMGMLKEGTPLPKSMDRILSGLKMAPKTKETCSTTPVVIKTPSPNPNRSRTPTHSPSRTPNRTPTPDKSTKSPLIVGRKEPFKIYRDPALVKAELEAN--PTYIQPPHTPPNPKQHHKIPSPSSSSPSLTTASSHSKLLSPSPHSAHLSPIALHSQPPLCSLSTTPHSAIPHPHLLPSLLPALSPSTTLLAGHPRIG---TLGLPHHPIALPGNS--------SLLGQTTGGAPMASLGLYPLLWPPFPNGGHSYPGLGLQPSKWTHQDHATISDSSVRRNTPSHWLSQPTPVNNADGQGLQPPLPIRPSSADPQRASRSSQHCTP------SSKTTEELDRRGIAEST--FIHSHLKSDLERIRTSMGKNGQTYSPVALESPPSQTKQPLVVYDLTGDRPNSYQEENRRILLESSEVAPFTAKLGSDREPR--YPRSPTPALPSKEREIELDREKDRDRERDVHAFRHALPPRPQSAHPSPTLTPSSYYASLSNSVENRPPQ----RKVPASKELYERLSASNSVAPVLTSSSQVSMRAQPPPLVKRQHEKEEGLLGKITEKLVHKASSMYAVEMASVERRGPGSSIISVSSSSRSVPLLHRAPIFHPPAPTTVVSKDSGNGRLSPPTLTPIQPMSLSEKGQKQQRPPTLLPEFKHVALDGKRHMPEKAAMSSQAFNTQWGGVIYGRENVGGHTKNGGVVKPQVATASVIVRPTSHTHTIINYTVSDSSVSQMHCSPIRPLESMSNLKSKEGNVQHKRGVLWTPLDTVHPIN-MTTQKEDLSTPINMTMKLINTAHPSHGVTHPLTNMNASHSKIDLIAEQCKKRDSGAIQPKT--EPSSSSYCTTRDFPHLKKHRAGLTAAISRANTHTIQPQHTTYPLNAMTNNSHLSESHFESLTALTTHTVCSAHVLEREKEPVFNTSTSESLASGTSCPAPTDKQGSPTNGYTAGSTIINQSAQSGQNNYH-KLKKAWLTRHSEQDRGSTDSQTLDGTKSAVILTNTSTYIPAKQEVNGLMDNLEDKNSLDSKKPKILKKKPTQETRKSNSIATTICSEDKKSVKADEKPVTTGKKSFLLDNVKPVLDKNCKLEAKESIVEDKKSTEKHSNLGHMKTEREKRAEKRPLESNSDSETGGDSGNESENGESRRRFKRQPKTSFKIKQNNSQKKKVEEEEEEEEAKANGTLQ-SAKDKP---QRIANSNGIPRSVLKDWRKVRKLKQTGEAFLQDDSCAEIGANVQKCRECRLD--RSRKAQEPTLSPVFCRFYYFRRLSYSKNGVIRVDGFSVSE-HTDEEAVTVWTGSTEDEEDKKRREMDLEMSKSILTFIGDQFCRLVKTEDTAYSWVK-KDTQIMWKRAVRGVREMCDACEATLFNMHWACHKCGFVVCMDCYKAR---------EKRKAKDKELYVWVRCVKN---QPHDLKNLMPTQIVPDSVLADMQNSLHSLKEKFAIS------------------------------------------SQRPGTETKS-----------MATTNGLSPLSDTD----QSDLNSRQISDQQKNSQHVTLRAHTER---REKAECDGVEAQSKKSTSPEQGSTLRDLLTSTAGKLRLGS--AGGAFAPVYNFSEQVTQNTR-VPNILDDIIASVVENKIPATKMAKAELKQDSLPEEEAGQRPDGVKLDESTLANPHATAPYDWLGNHRLLWLKDHRHQGNQRLFKENWTQEQPVLVSGLHKSLNANLWKPENFSREFSSLHSDLYNCRDG-SITNSKVKEFWDGFEDASKRPKSGKGESVVYRLKDWPSGEEFLALMPARYHDVMKFLPVPEYTDPEAHLNLASHLPSFFIRPDLGPRLCCAHGVTACPEQDFGTSNLHVEISDTMSILVYVGVAK-GNGASSKAGVLKLLEEEVLDESVKKRLKDPNETPGALWHIYMSKDLQKIQEFLHKVAAEQHTEADPETDSDSEWDSDADPLREGGWYLSPRLRQRLQDEYGVESRTLLQFHGDAVIIPAGALHQVMNLHSCIQVNVDFVSPEHAHNSYYLTQELR-PLRDLMNYEDKLQVKNIFFHSVKDAVATLRKHLKEESTVKVKQEES-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHC5-1", "uniprot_id": "KDM3_DROME", "id": "Q9VHC5-1", "name": "Lysine-specific demethylase 3", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQKELAALVATRTSRKRTISSTSFSISTR--------------TDPK---------------------------------------------------------------------------------------------------------------------------------------SIIEIHIFNDSLP---------------------------------------------IKRACCEVENPTLKAEQRVQQEE----ESLGQVPPLTEEEQQRHDEFRNSGSIFLQDLPCFKLQQAQPIAGSSPIP------------KCRECRRRNLATTEGEPSSVSDVYCRFYEFRRLQFNENGELCVVGFPNPYSEPSPEDIAIWQPDKNTPPTSG--YMDIQVCRYILLHAGDQFCYIWHQEAEALSLHQNTDGTIAWKKAVKGTREICDVCDTTLFNYHWTCRKCGFGVCLDCVKDRKEGLRLRRAENAAQKGCDEYHWLLCSDPSGPQEHVLTELMLTQIIAGDALNVLGRLLHEVRTLWQVP-----------------------------------------------------------------------------------------QVCGCLLSKQAIEDAQSKEVIQDMIKESQLKQHTSYSSLASEQKVHQQQRLDQLHATKLEFARELGVDYVPGR-VWTKETLGKDPITTAFDNLKHINFLRKGLAGLRRFLPPRTMTFAYSTQLAPG----------------VPHEFLCDGRLLRLTDAMHPDNRVLFQEVWKCGQPVMISEVARSLNLDLWHPQAFCRDFGDKPNDLINCLNGNLVPNQPMRHFWEGFQCMTKRLPDAYGKPMLLKLKDWPPGDDFAEILPTRFADLMKGLPMPEYTLRTGNLNIASCLPKMFVPPDLGPKMYNAYGSALHPDK--GTTNLHLDISDAVNIMVYVGIPQDGDTRPQMAATQKAIEIGGCDYITRARCQSPDVLPGALWHIFPARDADKIRDLLNRVTLEKGFRLEPDHD----------PIHDQNWYLDDKLRARLFKEYGVEGHPIVQCLGDAVFIPAGAPHQVQNLHNCIKVAEDFVSPENITHCYHLTHEFRRLSHSHTNHEDKLQIKNIIYHAIKDCCTILTRAVDERLNAELTKLNAD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .: : . . .:: . : . . :: :. :. : :: : .: :*: :. * : :::. . .. .: . * :: : :*.: : ****** : :.: .: * *:**** ****.:.:** : : **. . . . * :::* .. :*:: .: ** **:** : * * * : .* * **:**:*.**:**.*::**** **.*:**** .*:** * : *. :. : * *: * . * * ..** ***:....* : :* :: : : .:. . :. :. . * ** :: * .. : * :.* . . :.. :*:: . .* . : *: :: : ::* *.* : .* **:* *. **.::* : :.:* .**:.: :. :*.. ** ** :. :.* ::.**:**: :** . *:.:: :*** *.*::* ::*:*: *.:: **:*** .::*:** ** :*: *****:: *:* . :: **:***:: **.:.::****:.: *: . *. * :* * : * :... *******: .:* :**:::*:::: *: . *: * *::: .**:. :** ** .****. .::* ***:.:***: *** *:*.*::* ******: ..::**:*:* :. *::****:***::*::*: * .* : . ", "identical_positions": 218, "similar_positions": 277, "identity": "7.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-833", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BJS0-1", "uniprot_id": "DHX30_RAT", "id": "Q5BJS0-1", "name": "ATP-dependent RNA helicase DHX30", "aln": "-----------------------MFTLDSFRKDR-TQHRQRQCKLPPPRLPPMCVNP---APGGTISRASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEVEGYGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPTMPPTSWRQLNPENIRPAGTGGLSRSLGREEEEDEEEELEEGTIDVTEFLSMTQQDSHNPLRDSRGGSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLATLTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIEAFLSHYPVDSS--WISPELRLQSDDILPLGKDSGP---LSDPITGKPYMPLSEAEEVRLSQSLLELWRRRGPIWQEAPQLPVDPHRDTILSAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPAR-GGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAK-------LGKHQY--PHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPLGVRKIVLATNIAETSITVNDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRTSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLPSAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLRELRRALGRMVERSLRSELAALPLSVQQEHGQLLALLAELLR-----------GPCGSFDVRKTADD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99PU8-1", "uniprot_id": "DHX30_MOUSE", "id": "Q99PU8-1", "name": "ATP-dependent RNA helicase DHX30", "aln": "MVTPVCNSSTWQPKDSSFLSWPEMFSLDSFRKDR-TQHRQRQCKLPPPRLPPMCVNP---APGGTITRASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEVEGYGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPTMPPTSWRQLNPENIRPGGPAGLSRSLGREEEEDEEEELEEGTIDVTEFLSMTQQDSHNPLRDSRGGSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLATLTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIEAFLSHYPVDSS--WISPELRLQSDDILPLGKDSGP---LSDPITGKPYMPLSEAEEVRLSQSLLELWRRRGPIWQEAPQLPVDPHRDTILSAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPAR-GGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAK-------LGKHQY--PHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPLGVRKIVLATNIAETSITVNDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRTSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLPSAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLREFRRALGRMVERSLRSELAALPLSVQQEHGQLLALLAELLR-----------GPCGSFDMRKTADD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L2E3-1", "uniprot_id": "DHX30_HUMAN", "id": "Q7L2E3-1", "name": "ATP-dependent RNA helicase DHX30", "aln": "-----------------------MFSLDSFRKDR-AQHRQRQCKLPPPRLPPMCVNP---TPGGTISRASRDLLKEFPQPKNLLNSVIGRALGISHAKDKLVYVHTNGPKKKKVTLHIKWPKSVEVEGYGSKKIDAERQAAAAACQLFKGWGLLGPRNELFDAAKYRVLADRFGSPADSWWRPEPTMPPTSWRQLNPESIRPGGPGGLSRSLGREEEEDEEEELEEGTIDVTDFLSMTQQDSHAPLRDSRGSSFEMTDDDSAIRALTQFPLPKNLLAKVIQIATSSSTAKNLMQFHTVGTKTKLSTLTLLWPCPMTFVAKGRRKAEAENKAAALACKKLKSLGLVDRNNEPLTHAMYNLASLRELGETQRRPCTIQVPEPILRKIETFLNHYPVESS--WIAPELRLQSDDILPLGKDSGP---LSDPITGKPYVPLLEAEEVRLSQSLLELWRRRGPVWQEAPQLPVDPHRDTILNAIEQHPVVVISGDTGCGKTTRIPQLLLERYVTEGRGARCNVIITQPRRISAVSVAQRVSHELGPSLRRNVGFQVRLESKPPSR-GGALLFCTVGILLRKLQSNPSLEGVSHVIVDEVHERDVNTDFLLILLKGLQRLNPALRLVLMSATGDNERFSRYFGGCPVIKVPGFMYPVKEHYLEDILAK-------LGKHQY--LHRHRHHESEDECALDLDLVTDLVLHIDARGEPGGILCFLPGWQEIKGVQQRLQEALGMHESKYLILPVHSNIPMMDQKAIFQQPPVGVRKIVLATNIAETSITINDIVHVVDSGLHKEERYDLKTKVSCLETVWVSRANVIQRRGRAGRCQSGFAYHLFPRSRLEKMVPFQVPEILRTPLENLVLQAKIHMPEKTAVEFLSKAVDSPNIKAVDEAVILLQEIGVLDQREYLTTLGQRLAHISTDPRLAKAIVLAAIFRCLHPLLVVVSCLTRDPFSSSLQNRAEVDKVKALLSHDSGSDHLAFVRAVAGWEEVLRWQDRSSRENYLEENLLYAPSLRFIHGLIKQFSENIYEAFLVGKPSDCTLASAQCNEYSEEEELVKGVLMAGLYPNLIQVRQGKVTRQGKFKPNSVTYRTKSGNILLHKSTINREATRLRSRWLTYFMAVKSNGSVFVRDSSQVHPLAVLLLTDGDVHIRDDGRRATISLSDSDLLRLEGDSRTVRLLKELRRALGRMVERSLRSELAALPPSVQEEHGQLLALLAELLR-----------GPCGSFDVRKTADD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TE51-1", "uniprot_id": "A0A8N7TE51_DANRE", "id": "A0A8N7TE51-1", "name": "ATP-dependent RNA helicase DHX30", "aln": "-----------MAMSSALTPLRALLSLRSKTLEINKDIRSRWAFIRQYRSKPDVVHTRRHSPPETINKAHPDYL----HAKNLLYNTLSRSVGLSNVSQYLKFSCTDG-EVKRATVTLLWPVRIETEGFGSRKQEAERNAAAAALQKLCELGVYAPGK----------------------RRQE---------------------AGMLRMKDRQTSLCDNE--EENHLQSLPIQKKTQKDRAHGLVE---------EDSRLSEALAIFPRPRTLLGSVIQVATSSCRVRDLLQYKTSGGKVKVCELNVLWPTPMTFTASGRRRLEAEANAAALACLKLKELNLLDEQNKPLTHARYHQDQVREAGERHRQPCRMQIPEQLELRIQQYLSQYPVEAEVQKLWDEEEHQSSSISTAADDYDEDEFITDAITSKPYRALEPKEAEHLSQRLLSMWKRVGPAR--GAELPVDAHKESILEAVRSSQVVVISGETGCGKTTRIPRFLLEDGVLRGEGAECNVLVTQPRRISAVSVAQRVAHEIGPALQHCVGYQVRLESRPPERSGGALLFLTLGVLLKKLQSNPRLEGISHVIVDEVHERDVQTDLLLHLLRCVLSLRPELKVLLMSASGDSQRLAQYFGGCPVLRVPGFMHPVRARFLEDMQLDSRRPLLDMGSTQWSAEVRGRMGKEENNVTPDLDLVADVIDHIHRTGEPGAVLCFLPGWQEIKAVQQQLEEKQAYRSGSQIILPLHSSMAVSEQQVVFQRPPAGQRKIVLATNIAETSITIDDIVHVVDAGVQKEQNYDPRTKVSALNTVWISQANVTQRRGRAGRCQPGHSYHLFPRKQLERMEPFPVPEILRTPLESVVMQAKIHCPESKAEDFLSQVLDSPDTQAVRTAVKNLMDIGVLDASEDLTPLGHHVSCMSCDPRLGKVLVFSALFSCVQPVLSVVACLTRDPFYNSLQNRTLVSKAKAELSGSSGSDYLVFSRVVQSWREQH---SRDSRQDYLDKHTLSGASLRFIHGLMQQFSDNLCEAGLVDHSAECLRLSSPVNQQSKEEQLITAVLLAGLYPNLIQVKKGVVTKSGRFRAENVSFRTESGPVLLHRSSVNRDKQHLWSRWLTFFSAVKSSGQVFIRDSTVVHPLALLLLTDCDLSERVVGDRVEVALPGPALIRWEFSPAVWELLWDLRASIQAMIYRKLR-QSECKSSSEQRKDSELIDLLVDLLNNTDPDVSRDQEDALNSSNTENAEADSC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::* * : : *.* . : * * *:. :* **.:* * * :.**** ..:.*::*:*:..: * : *:* : *:.*: : ** :*.**:**:* :***:***** * : *: .* : * * .*: * .*: . ::* **. :: : . **:* * : :*. .**: ** *:.**..***:****. .::*:*::* * *.*:. *.:*** ****.*.***: *** :****** ***.*.*:*.:*:***** *: .:** ** :*:** :*:** : :*: :*.:***::. : * . **..* . ..* . ::*.**.*** .* * :*** **.:*:* ** ..:****.*:::**.*:.. ******:**********::*** * .*.**.***::***************:**:**:*:: **:******:** * ****** *:*:**:****** ***:*************:**:** **: : *.* *:::****:**.:*:::*******::*****:**: ::***: . :*. *: * * :.*:: : *****:*:: **. ****.:***********.***:*:* . :... :***:**.:.: :*:.:**:** * ***************::*******:*::**:.** :****.*:***:*:*** **********.*.:******.:**:* ** **********.:*:***** **..* :***:.:***: :** ** * :***** * **.**:::: :* ****.*.:*::*:* *::*:* **:******* .*****: *.*.** ** .****:*.* *.* .*.* .* **::**::: * ..********::***:*: ** **.:.::* *: *: *:**:*:..**:**********::* **:.*:*:.:.*::**:** :***:*::**: :* *****:* ****.*.**:***: *****:***** *: * * *. ::*... *:* * .. . .** ::* :: *: *.** : . . * *.:..:*: **.:**. .. .* : .:: * ", "identical_positions": 573, "similar_positions": 348, "identity": "45.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-838", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LYC7-1", "uniprot_id": "F1LYC7_RAT", "id": "F1LYC7-1", "name": "", "aln": "-----------------MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKVELTAVGSGSNARGTNPDGSTTEKLGHRSEDQPDDPQAKMDYVGNTAEAEGLLVPLSSPGDSLKLPTPDGTEASHSRANCSWTPLSTQMSKQVDCSPAGVKALDSRHSVGEKNTFILATLGTGVPVEGTLPLVTTNFSQLPAPICPPAPGSASGTPSVPDPFQVPLS--------------VPAPVPHSGLVPVQVATSASAPSPPLAPVPALAPAAPSVPTLISDSNPLSVSASVLVPVPVSAPHSVPVPLSAPAPTPLTVSVSAPPLALIQAPVPPSAPTLVLASVPTPVLAPMPASTPPAAPAPPSVP--MPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGT----------------------------VLTPNQPLVYIPPPSCGQPLSVAT---------LPTTLGVSSTLTLPVLPSYLQDRCLPG--VLASPELRSYPYAFSVARPLASDSKLVSLEVNRLSCTSPSSSTNSQ---------------PAPEG----VPGPLADTSLTTASAKVLPTSQPLLPAPSGSSVPLHPSKMP-----------GGTDQQTEGTSVTFSPLKSPPQ-LEREMASPPECS--EMPLDLSSKSN-------------RQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGSNVTSCLGSTSSPFVIFPEMVRNGDPSTWVKN-STALISTIPGTYVGVANPVPASLLLNKD-PNLGLNRDPRHLPKQEPISIID--QGEPKSTGVTCGKKGSQVAAEGQPSTVKSRYTPARIAPGLPGCQTKELSLWKPTGLTNMYPRCSINGKPTSTQ------------------QVLPVGWSPYHQASLLSIGISSAGQLTPSQGVPLRPTSIVSEFSGVSSLGSSE---------AVHGLPEGQPRPGGPFAPEQDAVTKNKT-CRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPNSGDIGVNQGSEESESHLCSDSTPKVEGPQAACGLKLAGDTKPKSQVLATYMSHELVLANPQNLCKMPELPLLPHDSHSKELILDVVPSSERGPSTDLSQLGSQVDLGRVKMEKADGDVVFNLANCFRADGLPAVPQRGQAEARAKAGQARVKREGVGVFTCKNSWQPDEETESLPPKKVKCNKEKEIEEEPQQQLPPQPHDKPMVRSSVGSKCRKLPGDPQEPTKKSPRGALDSGKEHNGVRGKHKH-RKPTKPESLPAGKRADGHEEGSLEKKAKS-----------SFRDFIPVVLSTRTRSQSGSICSSFTGLADSDMGSQEVFPTEEEEEVAPTPAKRRKVRKTQRDTQYRSHHAQDKT-----LLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEDEEEEG--LVKRKKRRRQKSRKYQTGEYLTEQE-----EQRRKGRADSKARKQKTSS-QSSEHCLRNRDLLLSSKAQGISDSPNGFLPNNLEEPACLENSEKP-------SGKRKCKTKHMANVSEEARSKGRWSQQKTRS--------------SKSPTPVKPTEPCTPS--KYRSAG--SEETSESPTARQIPPEARRLIVNKNAGETLLQRAARLGYKDVVLYCLQKHSEDVNHRDNAGYTALHEACSRGWTDILNILLQHGANVNCSSQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDNMKRFLSDHLSDLQGRAEGDPRASWD---------FYSSSVLEKKDGFACDLLHNPPGS--------AEQ-GDD-SEQDDFMFELSDK-----------PLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSS----------------------------RIFQARFPHLEITTLPKAEFYRQVASSQLLTPAERPGSLEDRSPPGSSETVELVQYEP----------------ELLRLLGSEVEYQSWSS---------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AQH4-1", "uniprot_id": "BCORL_MOUSE", "id": "A2AQH4-1", "name": "BCL-6 corepressor-like protein 1", "aln": "-----------------MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGGCQHFGSQEFCVSSSFSKVELTAVGSGSNARGTNPDGNTTEKLGHRSEDQSDDPQPKMDYVGNPAEAEGLLVPLSSPGDGLKLPTPDSTEASHSRANCSWTPLSTQMSKQVDCSPAGVKALDSRHGVGEKNTFILATLGTGVPVEGTLPLVTTNFSQLPAPICPPAPGSASGTPSVPDPFQVPLS--------------VPAPVPHSGLVPVQVATSASAPSPPLA------PAAPSVPTLISDSNPLSVSASVLVPVPVSAPHSVPVPLSAPAPTPLTVSVSAPPLALIQAPVPPSAPTLVLASVPTPVLAPMPASTPPAAPAPPSVP--MPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGT----------------------------VLTPNQPLVYIPPPSCGQPLSVAT---------LPTTLGVSSTLTLPVLPSYLQDRCLPG--VLASPDLRSYPCAFSVARPLASDSKLVSLEVNRLSCTSPSSSTNSQ---------------PAPDG----VPGPLADTSLTTASAKVLPTSQLLLPAPSGSSVPPHPSKMP-----------GGTDQQTEGTSVTFSPLKSPPQ-LEREMASPPECS--EMPLDLSAKSN-------------RQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGSNVTSCLGSTSSPFVIFPEMVRNGDPSTWVKN-STALISTIPGTYVGVANPVPASLLLNKD-PNLGLNRDPRHLPKQEPISIID--QGEPKSTSATCGKKGSQAGAEGQPSTVKSRYTPARIAPGLPGCQTKELSLWKPTGLTNMYPRCSINGKPTST-------------------QVLPVGWSPYHQASLLSIGISSAGQLTPSQGVPIRPTSIVSEFSGVSPLGSSE---------TVHGLPEGQPRPGGPFAPEQDAVTKNKN-CRIAAKPYEEQVNPVLLTLSPQSGTLALSVQPSSGDMGVNQGSEESESHLCSDSTPKMEGPQAACGLKLAGDTKPKNQVLATYMSHELVLANPQNLCKMPELPLLPHDSHSKELILDVVPSSERGPSTDLSQLGSQVDLGRVKMEKADGDVVFNLANCFRADGLPAVPQRGQAEARANAGQARVKRESIGVFTCKNSWQPDEETESLPPKKVKCNKEKEIEEEPRQQPPPQPHDKPMVRSSLGSKCRKLPGDPQEPTKKSPRGALDSGKEHNGVRGKHKH-RKPTKPESQPPGKRTDGHEEGSLEKKAKN-----------SFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVAPTPAKRRKVRKTQRDTQYRSHHAQDKT-----LLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEDDEEEG--LVKRKKRRRQKSRKYQTGEYLIEQE-----EQRRKGRADSKARKQKTSS-QSSEHCLRNRNLLLSSKAQGISDSPNGFLPDNLEEPACLENPEKP-------SGKRKCKTKHMANASEEARSKGRWSQQKTRS--------------SKSPTPVKPTEPCTPS--KYRSAG--PEEASESPTARQIPPEARRLIVNKNAGETLLQRAARLGYKDVVLYCLQKHSEDVNHRDNAGYTALHEACSRGWTDILNILLQHGANVNCSSQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDNMKRFLSDHLSDLQGRAEGDPRASWD---------FYSSSVLEKKDGFACDLLHNPPGS--------AEQ-GDD-SEQDDFMFELSDK-----------PLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSS----------------------------RIFQARFPHLEITTLPKAEFYRQVASSQLLSPAERPGSLEDRSPPGSSETVELVQYEP----------------ELLRLLGSEVEYQSWSS---------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5H9F3-3", "uniprot_id": "BCORL_HUMAN", "id": "Q5H9F3-3", "name": "BCL-6 corepressor-like protein 1", "aln": "-----------------MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTTGDCQHFGSQEFCVSSSFSKVELTAVGSGSNARGADPDGSATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGLLVPLSSPGDGLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPAGVKALDSRQGVGEKNTFILATLGTGVPVEGTLPLVTTNFSPLPAPICPPAPGSASVPHSVPDAFQVPLS--------------VPAPVPHSGLVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNPLSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPPLALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAPPSVP--MPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFTPAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAMQKVPLSFQPGT----------------------------VLTPSQPLVYIPPPSCGQPLSVAT---------LPTTLGVSSTLTLPVLPSYLQDRCLPG--VLASPELRSYPYAFSVARPLTSDSKLVSLEVNRLPCTSPSGSTTTQ---------------PAPDG----VPGPLADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMP-----------SGTEQQTEGTSVTFSPLKSPPQ-LEREMASPPECS--EMPLDLSSKSN-------------RQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSRSQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWVKN-STALISTIPGTYVGVANPVPASLLLNKD-PNLGLNRDPRHLPKQEPISIID--QGEPKGTGATCGKKGSQAGAEGQPSTVK-RYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVNGKPTST-------------------QVLPVGWSPYHQASLLSIGISSAGQLTPSQGAPIRPTSVVSEFSGVPSLSSSE---------AVHGLPEGQPRPGGSFVPEQDPVTKNKT-CRIAAKPYEEQVNPVLLTLSPQTGTLALSVQPSGGDIRMNQGPEESESHLCSDSTPKMEGPQGACGLKLAGDTKPKNQVLATYMSHELVLATPQNLPKMPELPLLPHDSHPKELILDVVPSSRRGSSTERPQLGSQVDLGRVKMEKVDGDVVFNLATCFRADGLPVAPQRGQAEVRAKAGQARVKQESVGVFACKNKWQPDDVTESLPPKKMKCGKEKDSEEQQ-----LQPQAKAVVRSSHRPKCRKLPSDPQESTKKSPRGASDSGKEHNGVRGKHKH-RKPTKPESQSPGKRADSHEEGSLEKKAKS-----------SFRDFIPVVLSTRTRSQSGSICSSFAGMADSDMGSQEVFPTEEEEEVTPTPAKRRKVRKTQRDTQYRSHHAQDKS-----LLSQGRRHLWRAREMPWRTEAARQMWDTNEEEEEEEEEG--LLKRKKRRRQKSRKYQTGEYLTEQED----EQRRKGRADLKARKQKTSSSQSLEHRLRNRNLLLPNKVQGISDSPNGFLPNNLEEPACLENSEKP-------SGKRKCKTKHMATVSEEAKGKGRWSQQKTRS--------------PKSPTPVKPTEPCTPS--KSRSAS--SEEASESPTARQIPPEARRLIVNKNAGETLLQRAARLGYKDVVLYCLQKDSEDVNHRDNAGYTALHEACSRGWTDILNILLEHGANVNCSAQDGTRPVHDAVVNDNLETIWLLLSYGADPTLATYSGQTAMKLASSDTMKRFLSDHLSDLQGRAEGDPGVSWD---------FYSSSVLEEKDGFACDLLHNPPGS--------SDQEGDDPMEEDDFMFELSDK-----------PLLPCYNLQVSVSRGPCNWFLFSDVLKRLKLSS----------------------------RIFQARFPHFEITTMPKAEFYRQVASSQLLTPAERPGGLDDRSPPGSSETVELVRYEP----------------DLLRLLGSEVEFQSCNS---------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BKM1-1", "uniprot_id": "A0A8M2BKM1_DANRE", "id": "A0A8M2BKM1-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQVDPSPMNVGDGGTVSRESSAPTQVSESMVGNPQQTLPLELRG------DVPQSQQNKLRVTTDCKTPDVCSEASNSNHCPQVPSSQP--HSN-VFSTDPVNTP--LPDRIEVSKGKIDGAGIFSTHQWPCGKKVTTEDPVNS-VHSNINLNKKTNAPAPTQPVISVPLGFQCST----------------------------LFKPGQPVAFLPTSNFSSPLCKIT---------LPPGLGQIAALREATASQFQKDCPAQSSCSSTTPMLKTYPYHFSVGRGPGAEKKHPSSGS-KVRCDSLSKGFQAR---------------VEHKGPMSSVAAPALALPVQQATQGSAPPTRYTISPTAAICCSPALANITTQSRLLSLVEKGSTFRGAEKTSLAYLKPKTLSTPEELNVSCPVEPR--DVPLDLSAKSK-------------RQKSIKDTQNNPSVATEHHSVEAHQKNITGSKKIHSASFHGSSSTFDTQRNGATQKSSSKLTNHHALEPNTSWVKSSSSGSLNNLPGTYVGVASPILASTLRSKDGKGAAFVEDLQTFAKQETISIID--QGEQ----PVCRERKAQFAVKGSQ-----------------HNKSGKLSTGTQQGFLSTQLCATVNSQPHRK-----------------------------------SVGGKGGTLFTPPVKSLWQPPCVHSQGASLQKKPSQT---------QAPKTKSTLSCERALFHNSHLSPTKVEDEKWEKAKSPLSNLESIVKQKTLETTALTGENYCNLSSVGSKRPEVVSIQNRCQDSTLQQTLTAGSPPFRTIEGQVIKTDRTSPQTDSTAALNRPE----ITTVPVPKDKGREKQTKQTENQSSDSRQKIKSSTP-SKRSSPSIKVEWKERKLVQHLEDET---------AKEKASERKISSHVKVEGIALSLLQSNTVEVEGEAKINGAKEEIPSKGKVSIIKQK--------NLKKHAKEKTPSEVQKKTAPRKQKDKDSP-----SVKQGLSHKKQKKD-VLPGVGKSVLKDGTGPGPKAGGKTRKGK------------SCPANVEHTDSNKIDSESSPCRSPQVDRDSGSLSSPGWPSKESDSQEEASPRLRRGRRRTDEALLRDWSFATPPTPP---PLDPPSTPPPVPVRRPRGRPRINPLPEEVDADKDRPTEGGDTSSIKKRKRCKNRKYQNGEYITEKDKVADGEEEKLGVEDGEATNEKTGVYPCLSATLTGEVPSPDVSPRRTLFTRSGLTRPQDSPPATHPNTDKP-------AGKRKFKSKHLCDTDEQKKLKTKKGSLGKRTGPLVLDEDGPPAKKTPTPLCASPKPPHSPLSGKKGTAG--KSGIPESTPSRPVPPEVRRLIVNKNAGETLLQRAARLGYQDVVLYCLEKDVREVNRRDNAGYTALHEACARGWTHIVQVLLKHGADVNCSAQDGTRPIHDAVAADNLPAVWMLLNHGADPTLATYSGQTAVKLAQSPSMKTFLKEYFTDLEGRTDQDPSLQWD---------FYSSSVFEKDQEPCWDFLLSQPEDE--GEEMFSEQVKERDADADCLLFEFSSE-----------PLLSCYHVQVSLTQGFCNWFLLADVLKRLKMSA----------------------------RIFRARYPQFEVVNIAQAELWKQVSVSQTCSPPDE---LQPEDDEDGEETVELVRCVP----------------ELQGLLGSSIQILRDDDNDNDEDDDDKSALRPCSR---------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQT4-1", "uniprot_id": "Q8IQT4_DROME", "id": "Q8IQT4-1", "name": "Protein piccolo", "aln": "MEPNRHHEYQTHHQPHPSMQHHPTHPHHQQPHHQQPHHPQQPIHQHHPPPPPPQPQQQHQPPQQIHQQQQQHPHHYQQLHHHPTSSTSVGSSSSASYVNHHPQHHPTSLAEDQRGSRSAIYMSRSTQPGLPPPHPHSSAQGSGAAGTSGSDPHMQYYTSNQNLAIKKMSDPHPMWSYKSQAVTTPAPAPGLRQHGNPALYPTGSTAYWPPPDEQLHHQQPSRYSYAKPGGPVTGSRPIQGPLPNSQRYYSEDIKYSTVPAASKVLTYAPPASSSQPQPPPPTSSSSANSSSVRHYELDVVNPSNPSNEHQQPSPNYGRKCPPHYETPPEQRSAGATPNSTGTPTSTSHHQSLYIPMPTFSTEKFQTTVHNAIEKYIRETPGPSLEYPRGGVAPVGRTGYYNQQPMKSSKAPPSVPQTATSSYVKMEPEHALAGGLPQPTRSSLYHNPYNVESRERDSSPAMATVPAPHGYPTKYGKLIQQQHAASGVGTGSSAPYQSYYHQGTPSPAAGAVASPTPAPLPPLAEAPGTIFGPGTGLNPGIPPHSSQPVPPPANSQQPASSSSSSNANFSTLQVYPHGPDICYQPGSQTQAQNQTQNHPNPAKKSPAVTKPNYRALINDMLKRNTASEQELNLQIIKKTLNMEPASSRNHSAPSRVIQQSAAPAAISIPSAPPPPPPAIHSPLDLSMRTVKQTADSTEYKYQRPSTDYKLPQGGLGGGLGLPRFDITPNFSAATRGGAPTSPAPTPVIRQAVAIQPAPVPPTVPVPPAVAAPALVIKTVQQMRPSVVETNPFAKRQQQLPPETSIVQVTKPTVELMPTPSPSPHNSSNPNYLGKKRHLQEYNQAAAKQARLDAESSGSLVSGAPVIAAPTSVVVVAPVPVIAVNEQALAAKREREMQSMSAESSTSAHLVPKMEPRIRTKAELKGFTFTPPVLVTSTTNASSTISPPRTPPNQITNHIQIKLEPAPPKATDLGLDDEQHSLGNLMDWGSTCNNLVEQLMSKVVVPPTLPANNPGIKLELSEDDLPVARILKRQPLAAPSLAGGDAESATTQLTTTTNGISSSLGNGSGQKKLSKVEREKKRQQQEQRIAARLAPKQGQSSSSESDTTELHKRNTARQKKPLLRKGRTRQRSPEAASIQQSSDEEQEKVSQRLSRKPRTSSEESKTKATSAKKDVKKEAKTPSNKTNNSASLTKIKKKTTDSSSLNKAKGDENPKQESQESTSSESDQDDNDNDNDEEEEDQEEDEEEPEEEDDDEEQDKKKEKRVGRRPGNTLKKRIAHKLNTMTRSKHRKELELQLANSKVLRNDKIIRNSTTKIKRKYVRKVVDSKKEMMVTRLRNKRGMNSDLGALNGRNSKLKGSKVGNSPGKPKTSPQQQLYLEEYRYKLALKIPHSLISINKLNKVASSLPDLERRDLSQELACFKRNRPKTKAASKQDFTPKSIIDVLHLRVTNGSTAGTQRKISVSAPASTNLQIHSETSQTSASTSLYEQSQQDNPTENQSLDDMSKRHFSIFDTKVLQSKTRTETKLQ----KHREIIREIFVGPERPASAPPECVQEADGGDAISYQKYEEFLQQMNSIASANDSKLARRSLMEDKSVTAPQCPHKRKYRCRKGSSGFDYIRKKKRPAPTQTQNHTQNQSQSQVSSQITQHILEHNQSAADERLEDTDSTIAGSSHLPPKVKTEMDVCREIQKWVLNKGVGQSTMHKAARQGLIDVVVYCLDRMNMNPDQKDNAGYTPLHEACTQGWLEIARILLQYGANHSEAAQSGIRPLHGAIENDHEEVVRLLLSYGADPLLATYSGQTPLMLASSKLMRGILRAHLSDAQSAAADIKPMRFNGPWEIFDAKEYGYDIFSNVPNTACDMSRALRKERKEAKQQRMSSNSDRTSNLNGLLAEKKEEQKPEDLDQDRVTTTIKQNGETSATKTGSATTTTATTMVKLELGTDEDSNNNKNNEELNANVENNLVTSVVNVKNEVKKEVEAEAETEAETETNAKANTNSSTRLDEDQTDIETMDSELNGDIFEFEEADVPLPPLYLLKDEGSDKWVLLNDLCNLLKVKSKDTLLNKLCPNNSNALASSQKHLLREFKIDDFLEKATCLQLLCAGEKLNMFSSSKVVLIKYNDSVRNLLGVKTILMKF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ..* . ..* . . . . . . *. . . . . * . :. . . . : .. . . .: .:. .: : . .* .: .* . *.. **. . * . : :: . .. : . . *: ** .: ::.: . : . * . . : . . . . ...:. . . . . . : :: *. : .: : :. ::. ::*: :. ** .. . .* : : :. . . . . .: *: :: . *. . . .: . :. .: :: . :: : . : :: . .: . * . * . . *. : :: ..: *. . . : . *. . .::. : . : . . : . ::: : : . : : . .. . . . *: .* . .: .:: . . : . : . . .: . : : : . : : .... : : : :. * *: : ::* . . . : *. * * : * .: . *. . .:.. ... : .:. : . :. . : : : :: :. . :: ..: *. : :... . :. :. . . . ..: : . * :. . *** : :: . : : * : . .:. . . . . . : . .: . : * :: ::**..*:: :::*** * ***:***:: : :::******.*****::** .* .:**::**: . ::*.* **:*.*: *: .: :**.:**** ********.: **.* *: :* :::* :. : :: *. .::.: . *: . .. : : : :: * ..: . : :.* :: . : .: :*::.: : : . * . .::* :. .. : :: . . : .*: . * * . :: . ", "identical_positions": 111, "similar_positions": 417, "identity": "5.19%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-849", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K1L0-1", "uniprot_id": "A0A0G2K1L0_RAT", "id": "A0A0G2K1L0-1", "name": "Tenascin", "aln": "MGAVTWLLPGIFLALFALTPEGGVLKKVIRHKRESG-----LNLTLPEENQPVVFNHIYNIKLPMGSQCSVDLESTSGEKDLSPTPESSGSFQEHTVDGENQIVFTHRINIPRRACGCAA-APDVKELLSRLEELEMLVSSLREQCTMGTGCCLQPAEGRLDSRPFCSGRGNFSAEGCGCVCEPGWKGPNCSEPECPGNCNLRGQCLDGQCICDQGFTGEDCSQLACPNDCNDQGKCVNGVCVCFEGYAGLDCGLEVCPVPCSEEHGMCVDGRCVCKDGFAGEDCNEPLCFNNCNNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGELTCPNNCQGHGQCEEGQCVCNEGFAGADCSEKRCPADCHHHGRCLNGQCECDDGFTGADCGELQCPNGCSGHGRCVNGQCVCDEGYTGEDCSQRRCPNDCHNRGHCVQGKCICEQGFKGFDCSEMSCPNDCHQHGRCVNGMCICDDDYTGEDCRDRRCPRDCSQRGRCVDGQCICEDGFTGSDCAELSCPGDCHGHGRCVNGQCICHEGFTGKDCKEQRCPSDCHGQGRCEDGQCICHEGFTGLDCGQRSCPNDCSNQGQCVAGRCICNEGYTGVDCSEVSPPKDLIVTEVTEETVNLAWDNEMRVTEYLIMYTPTHADGLEMQFRVPGDQTSTTIRELEPGVEYFIHVFAILENKRSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKKVTTTRLDAPSQIEVRDITDTTALITWSKPLAEIDSIELSYGIKDVPGDRTTIDLTHEDNQYSIGNLKPDTEYEVSLISRRVDMASNPAKETFITGLDAPRNLRRVSQTDNSITLEWRNVKADIDSYRIKYAPISGGDHAEIDVPKSQQATTKTTLTGLRPGTEYGVGVSAVKGDKEGDPATINAATEIDAPRDLQVSETTQDSLTLFWKTPLAKFDRYRLNYSLPTGQSIEIQLPKDATSHVLTDLEPGQEYTVLLTAEKGRHKSKPARVKASTEEVP------------------------SLEN----------------------------------------------------------------------------------------------------------------------------------------------LTVTEAGWDGLRLNWTADDLAYEYFVIQVQEANKVETAHNFTVLGNLRTADIPGLKAATPYRVSIYGVARGYKTPVLSAETFTG-KTPSLGEVTVAEVGWDALKLNWTAPEG-AYTNFFIQVLEADMTQTVQNLTVPGGLRSVDLPGLKAATRYYITVRGVTQDFSTAPLSVEVLTEEIPQLGGLSVTEVSWDSLTLNWTTDD-------------------------------------------------------------------------------------------LAYKHFIIQVQEANNVEAAQNLTVSGSLRVVDIPGLKADTPYRVSIYGVIQGYRTPMLSADVSTAKEPEIGNLNISDVTPESFNLSWTATDGIFDMFTIEIIDSNRLLQTAEHNISGAERTAHISGLPPSTDFIVYLSGIAPSIRTKTISTTATTEALPLLENLTISDTNPYGFTVSWTASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVLVSGFT-QGHQTKPLRAETITEAEPEVDNLLVSDATPDGFRLSWTADEGIFDSFVIRIRDTKKQSEPQEITLPSPDRTRDITGLREATEYEIELYGISRGRRSQPVSAIATTAMGSPKEIMFSDITENAATVSWRAPTAQVESFRITYVPVTGGPPSMVTVDGTDTETRLVRLTPGVEYHVSVIAMKGFEESDPVSGSLITALDGPSGLLTANITDSEALAMWQPAIATVDSYVISYTGERVPEITRTVSGNTVEFELHDLEPATEYTLSVFAEKGHQKSSTIATKFTTDLDSPRELTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTARIQALSGSLRSKLIQTIFTTIGLLYPFPRDCSQAMLNGDTTSGLYTIYINGDKTQALEVYCDMTSDGGGWIVFLRRKNGREDFYRNWKAYAAGFGDRREEFWLGLDNLSKITAQGQYELRVDLQDHGESAYAVYDRFSVGDAKSRYKLKVEGYSGTAGDSMNYHNGRSFSTYDKDTDSAITNCALSYKGAFWYKNCHRVNLMGRYGDNNHSQGVNWFHWKGHEYSIQFAEMKLRPSNFRNLEGRRKRA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80YX1-1", "uniprot_id": "TENA_MOUSE", "id": "Q80YX1-1", "name": "Tenascin", "aln": "MGAVTWLLPGIFLALFALTPEGGVLKKIIRHKRESG-----LNMTLPEENQPVVFNHIYNIKLPMGSQCSVDLESASGEKDLTPTPESSGSFQEHTVDGENQIVFTHRINIPRRACGCAA-APDVKELLSRLEELELLVSSLREQCTMGTGCCLQPAEGRLDTRPFCSGRGNFSAEGCGCVCEPGWKGPNCSEPDCPGNCNLRGQCLDGQCICDEGFTGEDCSQLACPNDCNDQGRCVNGVCVCFEGYAGPDCGLEVCPVPCSEEHGMCVDGRCVCKDGFAGEDCNEPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGELTCPNDCQGRGQCEEGQCVCNEGFAGADCSEKRCPADCHHRGRCLNGQCECDDGFTGADCGDLQCPNGCSGHGRCVNGQCVCDEGYTGEDCSQRRCPNDCHNRGLCVQGKCICEQGFKGFDCSEMSCPNDCHQHGRCVNGMCICDDDYTGEDCRDRRCPRDCSQRGRCVDGQCICEDGFTGPDCAELSCPSDCHGHGRCVNGQCICHEGFTGKDCKEQRCPSDCHGQGRCEDGQCICHEGFTGLDCGQRSCPNDCSNQGQCVSGRCICNEGYTGIDCSEVSPPKDLIVTEVTEETVNLAWDNEMRVTEYLIMYTPTHADGLEMQFRVPGDQTSTTIRELEPGVEYFIRVFAILENKRSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKKVTTTRLDAPSHIEVKDVTDTTALITWFKPLAEIDSIELSYGIKDVPGDRTTIDLTHEDNQYSIGNLRPDTEYEVSLISRRVDMASNPAKETFITGLDAPRNLRRVSQTDNSITLEWRNVKADIDSYRIKYAPISGGDHAEIDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKGDKESDPATINAATEIDAPKDLRVSETTQDSLTFFWTTPLAKFDRYRLNYSLPTGQSMEVQLPKDATSHVLTDLEPGQEYTVLLIAEKGRHKSKPARVKASTEEVP------------------------SLEN----------------------------------------------------------------------------------------------------------------------------------------------LTVTEAGWDGLRLNWTADDLAYEYFVIQVQEANNVETAHNFTVPGNLRAADIPGLKVATSYRVSIYGVARGYRTPVLSAETSTG-TTPNLGEVTVAEVGWDALTLNWTAPEG-AYKNFFIQVLEADTTQTVQNLTVPGGLRSVDLPGLKAATRYYITLRGVTQDFGTAPLSVEVLTEDLPQLGGLSVTEVSWDGLTLNWTTDD-------------------------------------------------------------------------------------------LAYKHFVVQVQEANNVEAAQNLTVPGSLRAVDIPGLKADTPYRVSIYGVIQGYRTPMLSTDVSTAREPEIGNLNVSDVTPKSFNLSWTATDGIFDMFTIEIIDSNRLLQTAEHNISGAERTAHISGLPPSTDFIVYLSGIAPSIRTKTISTTATTEALPLLENLTISDTNPYGFTVSWTASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVLVSGFT-QGHQTKPLRAETITEAEPEVDNLLVSDATPDGFRLSWTADEGIFDSFVIRIRDTKKQSEPQEISLPSPERTRDITGLREATEYEIELYGISRGRRSQPVSAIATTAMGSPKEIMFSDITENAATVSWRAPTAQVESFRITYVPMTGGAPSMVTVDGTDTETRLVKLTPGVEYRVSVIAMKGFEESDPVSGTLITALDGPSGLLIANITDSEALAMWQPAIATVDSYVISYTGERVPEVTRTVSGNTVEYELHDLEPATEYILSIFAEKGQQKSSTIATKFTTDLDSPREFTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYSARIQALSGSLRSKLIQTIFTTIGLLYPFPRDCSQAMLNGDTTSGLYTIYINGDKTQALEVYCDMTSDGGGWIVFLRRKNGREDFYRNWKAYAAGFGDRREEFWLGLDNLSKITAQGQYELRVDLQDHGESAYAVYDRFSVGDAKSRYKLKVEGYSGTAGDSMNYHNGRSFSTYDKDTDSAITNCALSYKGAFWYKNCHRVNLMGRYGDNNHSQGVNWFHWKGHEYSIQFAEMKLRPSNFRNLEGRRKRA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P24821-1", "uniprot_id": "TENA_HUMAN", "id": "P24821-1", "name": "Tenascin", "aln": "MGAMTQLLAGVFLAFLALATEGGVLKKVIRHKRQSG-----VNATLPEENQPVVFNHVYNIKLPVGSQCSVDLESASGEKDLAPPSEPSESFQEHTVDGENQIVFTHRINIPRRACGCAA-APDVKELLSRLEELENLVSSLREQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEVSPPKDLVVTEVTEETVNLAWDNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAP------------------------ELEN----------------------------------------------------------------------------------------------------------------------------------------------LTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTG-ETPNLGEVVVAEVGWDALKLNWTAPEG-AYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFT-QGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPFPKDCSQAMLNGDTTSGLYTIYLNGDKAEALEVFCDMTSDGGGWIVFLRRKNGRENFYQNWKAYAAGFGDRREEFWLGLDNLNKITAQGQYELRVDLRDHGETAFAVYDKFSVGDAKTRYKLKVEGYSGTAGDSMAYHNGRSFSTFDKDTDSAITNCALSYKGAFWYRNCHRVNLMGRYGDNNHSQGVNWFHWKGHEHSIQFAEMKLRPSNFRNLEGRRKRA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TRK9-1", "uniprot_id": "A0AB32TRK9_DANRE", "id": "A0AB32TRK9-1", "name": "", "aln": "MSSRGLTLSCLLLITLMALNHAGLVKKLIRQRREALNVPGIHNVTLSNSSRPVIFNHVYNIKVPGSPLCSVDLDAPEGSD-----VELRDAPSEHSVDGSNQIVFTHRINIPKQACGCTDGLPDLKDLLSRLEMLEGEVSTLREQCGAESTCCSAQVTGAIGTKPFCSGHGNYSTETCGCVCAPGWKGLNCTIPDCPGDCSDQGRCVNGKCECFEGFTGDDCSTDACLIDCGDNGRCLN--------------------------------GKCVCSEGFSGEYCTESDCLNNCLGRGRCVDGECVCDEPWTGFDCSELICPNDCYDRGRCENGTCYCDRGFTGEDCGALACPNDCSGRGFCIDGRCVCDAGYTGEDCSSLTCPNNCNDRGRCSNGVCICEVGFHGEDCGRISCPSNCNNRGHCVDGRCECDVGFQGHDCSELSCPNNCNNRGRCVNGQCVCDEGFGSEDCGLKTCPSDCYGRGQCVDGECVCFANFAGEDCSELRCPNSCQNRGRCIAGQCVCDEGFTGEDCSQRKCPNDCLGRGRCVDGRCVCQDGFKGQDCSVPTCPGNCNDHGRCVNGKCVCDEGFFGDACSDRSCLNDCSDVGQCVDGRCICDEGYIGEDCSDVSPPEDLTVTDVSTQKVNLTWRNEMLVTEYLITYVPTAPGGLQMDFRVAGDRTSATVSELEPGIEYLINVYAVLNNKRSIPVSARVATYLPQPEGLRFTSITDSTVEVVWEQLNFPFDGWELIFRNT-KEENGKIVNNLTPSQTTFEQQGLGPGQEYEVTLSVIKNNTRGPETSSTVVTRIDSPAQIEVADVTDRSAVISWSKPLAPVDGFKVSYGPSTDPLIHRDVELSASETQYSLEDLKPDTQYRVALSSQRGDVTSEPIIESFTTGLDAPSELRAVDQTDSSITLEWKNSRSSIDGYRIKYGPIAGGAHGEDMFPKKAGDTTWATITGLKPGTEYGIGVTAVQNERESEPATTNALTDLDPPRDLEVQSSTETSVDLVWKRPRAKISTYRLAYVSVEGRREEIELPASASTSTLSGLMPGMSYTVTLVAERGHRRSAPATVTASTASFTFYLANAFPEFGSAKGADDNIISFVSLENSETPFSGSGLEDPIGGSFTISNVSSHGFDLMWDSNKLSGFDSFTVEVTDFSGMWKEEVHLNGKVNDTKIRGLKSSTEYQVRLYGLSNNQRSSLLEAVAVTAPKSTSPDVVALTVKRVSAAQPSVSTSTLLTEDFKAEEPLSDLKVTEVGANSLRLSWQAPERAFSSFIIELNSTSNTSKDSIIKVSGEARHAHVEGLNADMNYEITLYGRKAGEKSQPISVFVKTEEQKPQIGSLSLSDVSWDSFNVSWIIEDGPAFDSFVIEVANSAGPE-RQNLSVSGDARDLWMSGLSPGTSYMITLYGVHQGSILGSINVEAATDRAPAMGNLYVSNVTSQSFFVSWNDTKGEIERFVLEIIDSSWQQEPIEYNLSQSVQSYEITGLRPTTDYIAYVTGVMKGRRTDSVSAVASTAAEPDLSGLVVSNVTSDSVSLSWRTGEKAFDNFIVEVRESALPSQASGRTFGAGVRSAVLNGLRGNTTYQIKLYATVAGANTDALTTVVTTEPKPELGRVVVSERLANSLTLSWSTLSGHFDGFAARVSDREQLYDVVELRLSGTERNTSVQGLVDSTVYDIMFYGVSHGRQTPSVYFNTSTASLPKVENLTVWDVTPYGFRVSWDADS-GFSHFQVKVSDSGQLLEPQELVVPGNEASLEVLGLITGIGYEVSVTGVSGTGLRSRPITTVAVTEAEPEIEHLFVSDVTPESFRLSWTTEDDVFDRFVLKVRDSRKLSHPREFSMSGDERTKVLTQLLGGTEYEIELYGVTLERRSQPVTAVVKTGLGALRDLHFSDITDTSAVVYWTLPRAQPDSYRITLIPIQGGSPMIVQVDGSQSQVSLRNLIPGETYQVSVIAVKGLEESEPVSDTFTTALDTPRSLTVVNVTDSSALLFWQPAVATVDGYMITYSADTVPPISEQVSGNTVEFEMNSLAPATQYTVSVYAIRDREKSLPATADFTTDVDAPRDLVASNIQTDSAVLSWTPPRAAITGYTLTFQNSDADVREVIVDPSVASHTLSNLRSTTKYTVILQAVSEDKRSRSISTEFTTVGMLYGHPRDCSEALLNGETSSGPYTIYINGDEKQPLRVYCDMTTDGGGWMLFLRRQSGKLNFYRNWRNYSAGFGDTSDEFWLGLSNLHKITAAKQYEIRVDLRDGSETVFAVYDRFYIGDPRSRYKIQIGAYSGTAGDSLTYHQNRPFSTYDSDNDIAITNCALSYKGAFWYKNCHRVNLMGKYGDSSHSKGINWFHWKGHEHSIPFAEMKIRPANFRNLEGRRKRS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: *. ::* : ..*::**:**::*:: * **.:..:**:***:****:* .. *****::..*.. * : .**:***.************::****: **:*:****** ** **:***** : ** . * :.::*****:**:*:* ***** ***** **: *:***:* :*:*::*:* * :****:*** ** **.*:*:*:* * *** :**:*: *.:. *:*** .*****:.****** :** ***********:***** ******:.******** :**: * :* * :*:***: *::* ***. ** :*:.:*** :* * *: ** * *** :.**..*..:*:**:*:* ** *: *.***: ***:*:.** **:*:*:*::** . **. :**.**: :*:**:* *:* .::**** : :**..*.:** *: ***:*::**** **:: .**.** *:****:*:*:*::** *:**. **.:*:.:*** :*:*:*.*** * *.::** .**.: **** *****:*** * ***:****:** **:*: :.***:* *** *****: *.** .**:*:***.**:**: : *****:**:*.*:*:*:**:************* ****:*.**.:::*** *: *::.*: **:**** **::*:*.:.* .:*::.* **.******::* ::******* . ...**:*:*::*** *:** :*:*:* **** :*.::::** . * : ::*: .:.***: :*:***:*.*:* *:* *::*:* *:* ****** :** *.***.******:* :: **.*****.**:** *.* .**. ** :*:***:******:**:**: ::*.:*** ** *::*.*:**.*..::: *: :.*. * **:. *** * *: ::** .::: .* .* ** .*.* * **:*:::* ** *.*** . . .*** *.***.* :.***.* * : *:. *:*:::.:.:.. :.* *. * ..: **:. * :::** * :: :*. . * .*.:*.: :::*.**::.:.* :* *: *.*:* :: : ***:*.*. *. :.**...* * **: ** *. .:.**. *: * :*.* *::*: :.: :.*. . *:.:*:::*:* . *.. *. ..:* . : **.. *.*::.:*..: * .* *:: .:* :**:*.: :*: .:*:.*** : .* *: *: .: * ::* :..* .:**:**.: :.** ** : : : *:: . :* :: .::* :** :****: * .**** *** *.. .*. * *.* ***:**:***:.:.*.: .**: ********** *:*.: * :::*: : :******:::*:***.**:.******:::.:** **:::**::* *.* *::: . :**: :* * .*********:: ****.*:*:..*.:*: ::: *****:.:*.* * * ** :*:*** :*: **.* :* ***:.::. * .* ** * **:**:**:***:***.:: **** * .* .*:***.** ****:****.*:*:*:.: ** ::. *******: : .* ***:* : ::* :. :** . ::.****:*:**::.*:::*:::*:*:* ****::*** *.::. *. *:****.*..:*::*::* .:*:*:. :**:. **. *.* ***:*:** .*:***:*:***:*:** ****:***: :.*.*:****:*****::****:.*: :**:**: *:***** :******.** **** ***:****:* .*:.:****:* :**.::***::: .********: **:.*.***:*.*.* ***************:*********:***..**:*:*********:** *****:**:***********:", "identical_positions": 1015, "similar_positions": 678, "identity": "42.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-855", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AE57-1", "uniprot_id": "A0A8I6AE57_RAT", "id": "A0A8I6AE57-1", "name": "Up-regulator of cell proliferation", "aln": "-----------------------------------------------------------MALLVFLPCTCIICFLSCLLRIWTNHFVLQCLFLTAVAGLETASLCRPRIEVELLVKGHSDLGEVAPEVKPSD------SQTSVAIADLEWREMEGDDCGFHYGDGTN-------------------------------------EAQDNDFPTVERSRLQEMLSLLGLETYQVQKLTLQDSLQISFDSMKNWAPQAPKDLPWHFLRKLQALNAEARNTTMVLDSPPEAWPTEKGGQTEEGMMYWDPAEDVAADIYSFSELPMPDTPVNPLDLLCALLLSSDTFLQQEVLLKMSLCQFALPLVLPDSENHYHTFLLWALRGVVRTWWFQPPRGLGSFLREDSVVLSRVPTFAFVRMDVSSNSKSQLLNAVLSPARRQWDCFWHRDLNLGTNPREIADGLVEISWFFPSGKEDLDVFPEPMAFLNLRGDIGSHWLQFKLLTEVSSAVFILTDNISKKEYKLLYSMRESTTKYYFILSPYRGKRNTNLRFLNRLIPVLKIDHSHVLVKVSSTDGEGFLRRIRAIMCSVARSPCRRMSVEDMAHAARKLGLRVDEDFEECQKAKDRMEKIVRKIKDVDAYKRDELRLQGDPARKAAQAEREFCQLQWASEP-PEKHRAELRRRALELRVQQNGQEPTSGVQEFILGVSSPSPSERQYFLRWMEWGLARLGQPRP----RQPPETLLTLRPKLGGPSDLNEPLWPEPLGVEHFLREMGQFYEAESCLVEAGRLPAGQRRFAHFPGLAVDLLLGGLPLELVDGATLSIPVRWVTGLLKELHVRLDRRSRLVVLSALGVPGTGKSTLLNTMFGLKFATGRSCSARGAFMQLLPVAEGFSQDLGCDQILVIDSGGLISGALASAGDRFELEASLATLLMGLSNVTVVSLAET-----KDIPPAVLHAFLRLEKMGHMPNYQFVYQNLHDLPVPSPKPRDRRQLLDPPSDLSRAATHLEKQGGGFRTLAGLT----ERQHVWHIPALWHGAPPMAAVSLGYSEAIFELKRCLLENIRNGLSNQNKN-IQQLIDLVRRL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5NCI0-1", "uniprot_id": "URGCP_MOUSE", "id": "Q5NCI0-1", "name": "Up-regulator of cell proliferation", "aln": "-------------------------------------------------------------------------------------------------------MASPGIEVELLVKGHSDLGEVAPEVKPSD------SQTSVAIADLEWREMEGDDCGFHYGDGTN-------------------------------------EAQDNDFPTVERSRLQEMLSLLGLETYQAQKLTLQDSLQISFDSMKNWAPQVPKDLPWHFLRKLQALNAEARNTTMVLDVPPEAWPAEKESQAEEEMMYWDPAEDVAADIYSFSELPMPDTPVNPLDLLCALLLSSDTFLQQEVLLKMSLCQFALPLVLPDSENHYHTFLLWALRGVVRTWWFQPLRSLGSFR-EDSVVLSRVPTFAFVRMDVSSNSKSQLLNAVLSPARRQWDCFWHRDLNLGTNPREISDGLVEISWFFPSGKEDLDVFPEPMAFLNLRGDIGSHWLQFKLLTEVSSAVFILTDNISKKEYKLLYSMKESTTKYYFILSPYRGKRNTNLRFLNRLIPVLKIDHSHVLVKVSSTDSEGFVRRIRAIMCSVARSPCRRVSVEDMAHAARKLGLRVDEDFEECQKAKDRMEKILRKIKDVDAYKRDELRLQGEPARRAAQAEREFCQLQWVPEP-PEKHRAELRRRVLELRVQQNGQEPTSGVQEFILGISSPSPSERQYFLRWMEWGLARLGQPRP----RQPPETLLTLRPKLGGPSDLTEPLWPEPLGVEHFLREMGQFYEAESCLIEAGRLPAGQRRFAHFPGVAVELLLGGLPLELVDGATLSIPVRWVTGLLKELHTRLDRRSRLVVLSALGVPGTGKSTLLNTMFGLKFATGRSCSPRGAFMQLLPVAEGFSQDLGCDQILVIDSGGLISGALASAGDRFELEASLATLLMGLSNVTVVSLAET-----KDIPPAVLHAFLRLEKMGHMPNYQFVYQNLHDLPVPSPKPRDRRQLLDPPSDLSR-ATHLEKQGGGFRTLAGLA----ERQHVWHIPALWHGAPPMAAVSLGYSEAIFELKRCLLENIRNGLSNQNQN-IQQLIELLRRL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TCY9-1", "uniprot_id": "URGCP_HUMAN", "id": "Q8TCY9-1", "name": "Up-regulator of cell proliferation", "aln": "-------------------------------------------------------------------------------------------------------MASPGIEVELLGKGHSDLGEVAPEIKASE------RRTAVAIADLEWREMEGDDCEFRYGDGTN-------------------------------------EAQDNDFPTVERSRLQEMLSLLGLETYQVQKLSLQDSLQISFDSMKNWAPQVPKDLPWNFLRKLQALNADARNTTMVLDVLPDARPVEKESQMEEEIIYWDPADDLAADIYSFSELPTPDTPVNPLDLLCALLLSSDSFLQQEIALKMALCQFALPLVLPDSENHYHTFLLWAMRGIVRTWWSQPPRGMGSFR-EDSVVLSRAPAFAFVRMDVSSNSKSQLLNAVLSPGHRQWDCFWHRDLNLGTNAREISDGLVEISWFFPSGREDLDIFPEPVAFLNLRGDIGSHWLQFKLLTEISSAVFILTDNISKKEYKLLYSMKESTTKYYFILSPYRGKRNTNLRFLNKLIPVLKIDHSHVLVKVSSTDSDSFVKRIRAIVGNVLRAPCRRVSVEDMAHAARKLGLKVDEDCEECQKAKDRMERITRKIKDSDAYRRDELRLQGDPWRKAAQVEKEFCQLQWAVDP-PEKHRAELRRRLLELRMQQNGHDPSSGVQEFISGISSPSLSEKQYFLRWMEWGLARVAQPRL----RQPPETLLTLRPKHGGTTDVGEPLWPEPLGVEHFLREMGQFYEAESCLVEAGRLPAGQRRFAHFPGLASELLLTGLPLELIDGSTLSMPVRWVTGLLKELHVRLERRSRLVVLSTVGVPGTGKSTLLNTMFGLRFATGKSCGPRGAFMQLITVAEGFSQDLGCDHILVIDSGGLIGGALTSAGDRFELEASLATLLMGLSNVTVISLAET-----KDIPAAILHAFLRLEKTGHMPNYQFVYQNLHDVSVPGPRPRDKRQLLDPPGDLSRAAAQMEKQGDGFRALAGLAFCDPEKQHIWHIPGLWHGAPPMAAVSLAYSEAIFELKRCLLENIRNGLSNQNKN-IQQLIELVRRL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BJH6-1", "uniprot_id": "A0A8M2BJH6_DANRE", "id": "A0A8M2BJH6-1", "name": "", "aln": "MDCCPTVEIETTNESTGEDTKDKQQVFTCSAETHQEEVAKLQNVPAPGEISVQHIGTSSITLAWNSPENITTFELTCFNPTTTKTFTISNASAMEVEDLSPETEYAFTIISVSVNGDRSAGTELTASTKPVPPDKFKVENVGTTSVTLIWDVSGYKEKNFHVVCRQNGRNIQDDMTESGSVVFSDLSPGNKYSFHITRVLPNGIRSKEAVTYAQTKTNIQGLLQDLGLEQYYPNKLSLSDVLQIDKSSVTDEPAQFLSSLPWLLLKKLMMVNVTARSVKYAPD---------------------DDLSTLDIYNDTSIFQIDQNVNVNPLDIVTTLFHCSDGFLQQEMVSKMSMCQFSVPLLLPDCDGQQCMYMLWAMRDIVKKFRPHSLSDQKGFV-EDRIVHSELPLVSFVRLGDCSISKSQILNKLLSNPQQYHDTFVHRDMDCGDIPRKISDGLVEMSWYLPCGNKNIDVFPEPVAFANLRGDISTFETQYSFLCQTSTAVFVFFENLDTN-YKLLTNQHAKAQVYLVGNAQS---KTFNLHQLKSTALEMNLKKDNIILKMKQND-AHFVKNLHTTVNYIINNHPIKACLEKMDTIAHELGILVDEDTEDCQKAKNNAHVIIKGIQDTLQFKEDQLPLQGKIWKDLAKLEKEECRLRKAGDQNIEIYKSDLQIKKIELRKLQNKYDISEAMSCFISALSTSS-QERTYFLKWMRMNLDNLSRTNLSDLREQYKEKCQHFSENKEEIAQLDQQISNSSLGVEHFLREMGQLYEAAVSLSEN---LESRQQMLHLPKLCAKLMLNGFPLELVDGDASNIPLRWVSDVLKYLNSLVQPNNKIMVVTVLGVQSTGKSTLLNTMFGVQFAVSSGRCTRGAFMQLIKVKDDIKQQLGCDYLVIIDTEGLKSPELAKLDDSHEHDNELATLVVGLSDVTIINIAMENSTEMKDILQIVVHAFLRMKEIGKKPKCQFVHQNVADVSAHDKNMRDRKLLLEQLNEMTEAAARMENK-EEYKMFTDVMEYD-PETCNWYIPGLWHGNPPMAPVNAGYSEAVYDFKKNMAEIIAQCKCNTHVNNITDFLEWTKSLWNAVKYENFIFSFRNSLVADAYMRLCAEYNRWEWSFKKEMHSWLTQAETRVSNFEIFKQKSDKSDLKDILFKLKQEAVTKLDTLEKTTMDNLSKYFEQTEGHVFLVEKYKEGFVSSIKSLRRVNESSLVTQLETIVEIRRGMNKLDNIKKKFTDTMEKKVLSLLEELRKYNDAQKTDEELEQFFEEIWQESVNELSNTGLRKISIFDCVFKELRDKMKHKGSSVTEQLVNVKLENYGQGEFKIKKEIFFKRWYKRMTNDNSSMQLQNLAENIIQTCCQVVLEKMARHSDYHDAYIQEILHIIDNRLKSNKNIGFSDDFELSLKLYVCGFSAKSFQDMHDHFIMQNDPRRCLDRFKGKYQNDFKDLFYDRDQCQRKAEEFTKLCLKPAVEAFIYSSLGPDIVDQMLQGKNAFQFSTRAFFQYSLLKQLVNEDKFEQYEKYISFYESFVKGWIEDQIIKHFSSNNKVSELEECHLRGITKEILEAVKSAQNETDESGIKEFIQCICRKLGQKLIIPKDALETVMVLNNASQESFACWLSKSVEEMEQTVKKQLKKIDIKGKLFKLKIKPQDELFKRVFGCGKQCPFCSTPCEAGGEAHSEHCASVHRPQGIGRYRKVNSEKLVTNICSTNVQSERKFECFETKYSFHPYKRYREIFPDWHIPADTSIQASDYWKYVMARYNTKFAEKYNAQPADIPVIWKMITKQQAEKSLKEAFSVK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .:* *::.. *. ....: . * * .: *: * .::: : ::.:* :*. **** * :**:*.* ***. .*:.: ..* ..*** :*:** :*. **... . * * . : : :. *****:: :*: .** *****: **::***::**:***.:.: ::***:*.:*:.: :. . .* ** :* *. * .:***:. .* ****:** :** :: * * ***:: * .*:*:*****:**::*.*.:::*:****:** ******.:. *:.:* : *:***:: :*:..: **** . : .: * . : :. **: *: :::.:.::::*:...* *::.::: : : . : .:*.* *::**: **** *:*****:. . * : *:* ::.*:* ***. : *: *:* *:*: . : * ::::*: : :*** ** : :..:. ** .:*:.* .*: ***:**. .* .:.:.. .* *. : : ::: : : ..************:*** .* * .:::: *:* :. .*:* *:****:** : .:*:***:.:** *: :: ..:::*::.:** .************::**.. . .*******: * :.:.*:**** :::**: ** . *:. .* .* : .****::***:**::.:* *** ::*****::: *: *: ***:**: *:.. . . **:: **: .:::. *:::*:: :: ::.: . *:**.**** ****.*. .****::::*: : * * : .* : * * :::: : * ", "identical_positions": 304, "similar_positions": 335, "identity": "16.84%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-858", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D9E0-1", "uniprot_id": "S22AH_MOUSE", "id": "Q9D9E0-1", "name": "Solute carrier family 22 member 17", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MPSARFGRRGIVLLTLGLVGPCGVGGAAAGSSTGIMALRFLLGFLLAGVDLGVYLMRLELCDPTQR-LRVALAGELVGVGGHFLFLGLALVSKDWRFLQRM-ITAPCILFLFYGWPGLFLESARWLIVKRQIEEAQSVLRILAERNRP-HGQMLGEEAQEALQELENTCPLPATSTFSFASLLNYRNIWKNLLILGFTNFIAHAIRHCYQPVGGGG--SPSDFYLCSLLASGTAALACVFLGVTVDRFGRR-GILLLSMTLTGIASLVLLGLWDYLNDAAITTFSVLGLFSSQASAILSTLLASEVIPTTVRGRGLGLIMALGALGGLSCPAQRLHMGHGAFLQHVVLAACALLCILSIMLLPETKRKLLPEVLRDGELCRRP------------SLLRQPPP----NRCDHVPLLATPNPAL--------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NKX4-1", "uniprot_id": "S22AV_HUMAN", "id": "A6NKX4-1", "name": "Putative solute carrier family 22 member 31", "aln": "MEQEARVLRAAGGFGRARRLLASASWVPCIVLGLVLSSEELLTAQPAP-HCRPDPTLLPP--ALRALRGPALLDAAIPRL---GPTRAPAEALGVLSPSYLAPLTRAPRPSSWASCSGAAAGPT------WNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGRRAVFVASLVLTTGLGASEALAASFPTLLVLRLLHGGTLAGALLALYLARLELCDPPHR-LAFSMGAGLFSVVGTLLLPGLAALVQDWRLLQGLGALMSGLLLLFWGFPALFPESPCWLLATGQVARARKILWRFAEASGVGPGDSSLEENSLATELTMLSARSPQPRYHSPLGLLRTRVTWRNGLILGFSSLVGGGIRASFRRSLAPQ--VPT-FYLPYFLEAGLEAAALVFLLLTADCCGRR-PVLLLGTMVTGLASLLLLAGAQYLPGWTVLFLSVLGLLASRAVSALSSLFAAEVFPTVIRGAGLGLVLGAGFLGQAAGPLDTLHGRQGFFLQQVVFASLAVLALLCVLLLPESRSRGLPQSLQDADRLRRS------------PLLRGRP------RQDHLPLLPPSNSYWAGHTPEQH------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TFR5-1", "uniprot_id": "A0A8N7TFR5_DANRE", "id": "A0A8N7TFR5-1", "name": "", "aln": "MEYETKIYPQVGGYGRYNRIITLFSWFPNFAVSLNLFTDVFFTLVPESYHCKPDQALLPPSALLSNLSRQAYLNLTVPWLKGSGFSHCELYKYPVNVSNYTDDVERDVVSCTGGWEFSKPAGLQNNLVTEWNLVCDDYWKIPLQHICFMTGWTLGYILLGTLCDWLGRRRALLLSVVLSGLLGIMACISNSPSAFPFLRLCQGSTLAGVFLSSYIARLEWCDPSHR-LMVSMVSGFFAVFAELLLPGLAVLCRDWPVLQAVATLPLLLLLSYWCCASVFPESPRWLLATAQIPQAKECLQSFSARNGMCVSDELYPAETLLSEIDEAFPEDVQPEYHHVFELRHTRVIWKNCLILGFTLFIGTGIQYCFTRNLHIY--SPH-FYFSYFLRVLTGALACIFLCVTVDRYGRR-GMLLLAAIITGLSSLLLLALTQYLHGGLVLVLSVVGLLSSQALAMLSMFFGSEVMPTIVRGGTLGLIMSAGCIGMAASSLMELQNNGGYFLHHVIFASFAVLSVLCIMLLPESKHKPLPDSLKDGERQRRPPLFLSRMSRDNPPLLRTEPNGPEYNRDNYSRLVSATKKMLSKDTLPYKISSSTQAPLLSSNGAAPDAQEDSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDV7-1", "uniprot_id": "Q9VDV7_DROME", "id": "Q9VDV7-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "-MDLQRVLEKCGNFGPYQILLLGLYGYTNIVSSLHYFSQTLISFTPSHRCSAPVEEFSQNFTELLSCS----------------------------VIQYDVDMTSFRDNKCSSWDFDKESNYES-ITTELEWVCDDAYKLAVGQSFFFIGSALGSIFFGYLADRIGRLPACVLSTLTGASGDFFTSFVGSLPMFSFTRFISGLSMDTQYVLMYILVFEYLSPQHRTFGLNIILGVFYSIGLMISPWIAIWLGNWRSYLWAASLPALGMLIFP---LFLHESVEWLLTKGKFDKAVNNLKSVAKFNGRQVEDSVFDEFIKHYREKLNSAQ--KKSSDTFMGMLRTPRLRKFTIILLIKSMIITIAFDILSRNVEGVGISPFKLFSYSGFVVLPGGLSIILFQNKIGRKGMACASLLVGAFITATTGYLVGTLDPANYSVLLGFMVCLARFGAVVAYDAEAQYAAEIIPTSVRGRGVANIHVVGNAFAFFSSYIIYLGTFYKPLPSLLISFLLIIGACLCLTLPETLHKQLPQTLEEGEIFAKG------------EKWYFFPCFSRKRQSNKSESQLESANEITK------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :** : : . . * . : *: * : : *: :* .* :* : . : .. . :: :* :* :: : .: ** **:.. :. .* . * .: . : . : . : :** :. :: * :: : . : ::: . . * **:. :*. :. :: . : : :. :.: . . .:*::** :** :. : * . * :::: :: : ***: : **: *.:.: : * : : . ", "identical_positions": 38, "similar_positions": 105, "identity": "6.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-860", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z143-1", "uniprot_id": "SEM4F_RAT", "id": "Q9Z143-1", "name": "Semaphorin-4F", "aln": "MLARAERPRPGPRPPPVFPFPPPLS-LLLLLAILSAPVCGRVPRSVPRTSLPISEADSYLTRFAASHTYNYSALLVDPASHTLYVGARDSIFALTLPFSGERPRRIDWMVPETHRQNCRKKGKKEDECHNFIQILAIVNASHLLTCGTFAFDPKCGVIDVSSFQQVER------LESGRGKCPFEPAQRSAAVMAGGVLYTATVKNFLGTEPIISRAVGRAEDWIRTETLSSWLNAPAFVAAMVLSPAEWGDEDG-DDEIFFFFTETSRVLDSYERIKVPRVARVCAGDLGGRKTLQQRWTTFLKADLLCPGPEHGRASGVLQAMAELRPQPG-AGTPIFYGIFSSQWEGAAISAVCAFRPQDIRAVLNGPFRELKHDCNRGLPVMDNEVPQPRPGECIANNMKLQQFGSSLSLPDRVLTFIRDHPLMDRPVFPADGRPLLVTTDTAYLRVVAHRVTSLSGKE---YDVLYLGTEDGHLHRAVRIGAQLSVLEDLALFPEPQPVESMKLYHDWLLVGSHTEVTQVNTSNCGRLQSCSECILAQDPVCAWSFRLDACVAHAGEHRGMVQDIESADVSSLCPKEPGEH-PVVFEVPVATVGHVVLPCSPSSAWASCVWHQPSGVTALTPRRDGLEVVVTPGAMGAYACECQEGG---AARVVAAYSLVWGSQRGPSNRAHTVVGAGLVG-FLLGVLAASLTLLLIGRRQQRRRQRELLARDKVGLDLGAPPSGTTSYSQDPPSPSPEDERLPLALGKRGSGFGG--------------FPPPFLLDSCPSPAHIR----------------------------------LTGAPLATCDETSI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z123-1", "uniprot_id": "SEM4F_MOUSE", "id": "Q9Z123-1", "name": "Semaphorin-4F", "aln": "MLARAERPRPGPRPPPVSLFPPPSSLLLLLLAMLSAPVCGRVPRSVPRTSLPISEADSYLTRFAAPHTYNYSALLVDPASHTLYVGARDSIFALTLPFSGEKPRRIDWMVPETHRQNCRKKGKKEDECHNFIQILAIANASHLLTCGTFAFDPKCGVIDVSSFQQVER------LESGRGKCPFEPAQRSAAVMAGGVLYTATVKNFLGTEPIISRAVGRAEDWIRTETLSSWLNAPAFVAAMVLSPAEWGDEDG-DDEIFFFFTETSRVLDSYERIKVPRVARVCAGDLGGRKTLQQRWTTFLKADLLCPGPEHGRASGVLQDMTELRPQPG-AGTPLFYGIFSSQWEGAAISAVCAFRPQDIRAVLNGPFRELKHDCNRGLPVMDNEVPQPRPGECITNNMKFQQFGSSLSLPDRVLTFIRDHPLMDRPVFPADGRPLLVTTDTAYLRVVAHRVTSLSGKE---YDVLYLGTEDGHLHRAVRIGAQLSVLEDLALFPETQPVESMKLYHDWLLVGSHTEVTQVNTSNCGRLQSCSECILAQDPVCAWSFRLDACVAHAGEHRGMVQDIESADVSSLCPKEPGEH-PVVFEVPVATVGHVVLPCSPSSAWASCVWHQPSGVTSLTPRRDGLEVVVTPGAMGAYACECQEGG---AARVVAAYSLVWGSQRGPANRAHTVVGAGLVG-FFLGVLAASLTLLLIGRRQQRRRQRELLARDKVGLDLGAPPSGTTSYSQDPPSPSPEDERLPLALGKRGSGFGG--------------FPPPFLLDSCPSPAHIR----------------------------------LTGAPLATCDETSI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95754-1", "uniprot_id": "SEM4F_HUMAN", "id": "O95754-1", "name": "Semaphorin-4F", "aln": "MPASAARPRPGPGQPTASPFP------LLLLAVLSGPVSGRVPRSVPRTSLPISEADSCLTRFAVPHTYNYSVLLVDPASHTLYVGARDTIFALSLPFSGERPRRIDWMVPEAHRQNCRKKGKKEDECHNFVQILAIANASHLLTCGTFAFDPKCGVIDVSRFQQVER------LESGRGKCPFEPAQRSAAVMAGGVLYAATVKNYLGTEPIITRAVGRAEDWIRTDTLPSWLNAPAFVAAVALSPAEWGDEDG-DDEIYFFFTETSRAFDSYERIKVPRVARVCAGDLGGRKTLQQRWTTFLKADLLCPGPEHGRASSVLQDVAVLRPELG-AGTPIFYGIFSSQWEGATISAVCAFRPQDIRTVLNGPFRELKHDCNRGLPVVDNDVPQPRPGECITNNMKLRHFGSSLSLPDRVLTFIRDHPLMDRPVFPADGHPLLVTTDTAYLRVVAHRVTSLSGKE---YDVLYLGTEDGHLHRAVRIGAQLSVLEDLALFPEPQPVENMKLYHSWLLVGSRTEVTQVNTTNCGRLQSCSECILAQDPVCAWSFRLDECVAHAGEHRGLVQDIESADVSSLCPKEPGER-PVVFEVPVATAAHVVLPCSPSSAWASCVWHQPSGVTALTPRRDGLEVVVTPGAMGAYACECQEGG---AAHVVAAYSLVWGSQRDAPSRAHT-VGAGLAG-FFLGILAASLTLILIGRRQQRRRQRELLARDKVGLDLGAPPSGTTSYSQDPPSPSPEDERLPLALAKRGSGFGG--------------FSPPFLLDPCPSPAHIR----------------------------------LTGAPLATCDETSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BE08-1", "uniprot_id": "A0A8M2BE08_DANRE", "id": "A0A8M2BE08-1", "name": "", "aln": "MNSVTG---------------------LFVLSVLLCSTLSSWSATVNSNGAEFPRLSGFG---------NLSTFLLHSESGMLYLGARDAVIVVDTAKLS--KKMIEWSVPEDRRKSCVAKGKTEDDCRNYVRLLEFLDDGRIYACGTFAFDPQCAFINISTFSLEKQDDGFIKMETGKGKCPFEPSQPYTAVMAGGILYTAVTSNFLGTMYDISRATGIEQERIRTEQSINWLSDPEFISSAFIQEDAKNNPTGEDDKIYFFFTEVAKEYDLYTKVKVPRVARVCKSDVGGMKTLQRRWTTFLKAQLVCEDRASGQRFNILTDVFTVQHQPGDPSSTHFYGIFTSQWEREELSAVCVYSLEEITKVMNGPFKELKKSCEN--WINPEPIPTPRPGQCLNSDQRELGFESSLKLPDKVLTFMRDHPLMENSVVAV---PLMIRYGITYTKLAVTLTPAFSGQKQHITTVLHLGTDHGELHKVAVVGPNATLIEEITLFSAQEPVNNILLYKGEAVVGSPHSLVKLPILGCSLYSSCEVCARAGGLGCIWRHNRPACAMAK-----PGEVVEAEDLVRQCNKREGLCSPPVIEMRVVEGLRVLLSCVQLSPRP-CHWDHPPGSHTRHHNYD-LEVQITNKSLGIYVCLCDEAGRDQPPCRKAVYQLTLDNPRVEGNKAIAGSRHFMASHIFLFVIGFMLGGILLFLIYKRQGGMTVGGNSSSTLEKGRDLLHSTDTPQSPSSASLLSEAVPITEKRNGTLNGHGHSMHPGGHNGRHIYTNSSGLKLQESAVNLADELDGRERAGPDGEEEGLEEGLSEMEEAFSKMPCLQGAPLAQCEESSI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 255, "similar_positions": 261, "identity": "30.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-861", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88201-1", "uniprot_id": "CLC11_RAT", "id": "O88201-1", "name": "C-type lectin domain family 11 member A", "aln": "MQAAWLLGALLVPHLLSFGHGARGHGKEWEGVWGGALEEERDRESLMLKNLQEALGLPTGVGNKDNLAENSEGKEVWEATETQGEEEEEETTTTPSSSPTPFPSPSPTSEDTVTYILGRLASLDAGLHQLHIRLHVLDTRVVELTQGLRRLRDAASDTRDSVQALKEVQVRSEQEHGRLEGCLKGLRLGHKCFLLSRDFETQAAAQARCKARGGSLAQPADRQQMDALSRYLRAALAPYNWPVWLGVHDRRSEGLYLFENGQRVSFFAWHRALSPESGAQPSAASHPLSPDQPNGGILENCVAQASDDGSWWDHDCERRLYFVCEFPF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88200-1", "uniprot_id": "CLC11_MOUSE", "id": "O88200-1", "name": "C-type lectin domain family 11 member A", "aln": "MQAAWLLGALVVPQLLSFGHGARGPGREWEGGWGGALEEERERESQMLKNLQEALGLPTGVGNEDNLAENPEDKEVWETTETQGEEEEEEITTAPSSSPNPFPSPSPTPEDTVTYILGRLASLDAGLHQLHVRLHVLDTRVVELTQGLRQLRDAASDTRDSVQALKEVQDRAEQEHGRLEGCLKGLRLGHKCFLLSRDFETQAAAQARCKARGGSLAQPADRQQMDALSRYLRAALAPYNWPVWLGVHDRRSEGLYLFENGQRVSFFAWHRAFSLESGAQPSAATHPLSPDQPNGGVLENCVAQASDDGSWWDHDCERRLYFVCEFPF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y240-1", "uniprot_id": "CLC11_HUMAN", "id": "Q9Y240-1", "name": "C-type lectin domain family 11 member A", "aln": "MQAAWLLGALVVPQLLGFGHGARGAEREWEGGWGGAQEEEREREALMLKHLQEALGLPAGRGDE-NPAGTVEGKEDWEMEEDQGEEEEEEATPTPSSG----PSPSPTPEDIVTYILGRLAGLDAGLHQLHVRLHALDTRVVELTQGLRQLRNAAGDTRDAVQALQEAQGRAEREHGRLEGCLKGLRLGHKCFLLSRDFEAQAAAQARCTARGGSLAQPADRQQMEALTRYLRAALAPYNWPVWLGVHDRRAEGLYLFENGQRVSFFAWHRSPRPELGAQPSASPHPLSPDQPNGGTLENCVAQASDDGSWWDHDCQRRLYYVCEFPF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T6P7-1", "uniprot_id": "A0A8N7T6P7_DANRE", "id": "A0A8N7T6P7-1", "name": "", "aln": "MTLTKILAAVLGFCALSSCDSADNTTR-------------PPATIITTADLSQAREFNEG---------IVRGRG------DTPDILEPEPTTAVSDM-----------ESTYNYILSRLAAMDQAIHRLNVGQYTLDIKVTQLLEKVSRLDNRLGDTEDAIQQISSYCKDNRKEIGRLEGCQKGRKIGYKCVLAYRVYETYADASKKCQERGGRMAMPRDRKEQEALAEYVKSVFHG-NWPVWLGINDERSEGLYLFEDTTRVTYFQWRK--------------HFLSS-QPDGGKRENCVAMSSDDGDWWDTYCERRMYYLCEFDV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : :*.*:: *. ..* . : .*.:* : * ..: : * * *.: *. *. .***.***.:* .:*:*:: :.** :*.:* : : :* : .**.*::* :.. .:* ****** ** ::*:**.* * :*: * *. :* *** :* * **:: :**:.*:::.: *******::*.*:*******: **::* *:: * **. **:** ***** :****.*** *:**:*::*** .", "identical_positions": 105, "similar_positions": 86, "identity": "32.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-863", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O94812-1", "uniprot_id": "BAIP3_HUMAN", "id": "O94812-1", "name": "BAI1-associated protein 3", "aln": "MRPRGAAFAAGPPGDLHLGTAIGFAGAIWRSRSPAMSTLLDIKSSVLRQVQVCPSFRRRTEQDPGSASADPQEPATGAWKPG--------DGVEFFAHMRLMLKKGEGRQGLPCLEVPLRSGSPAPPEPVDPSLGLRALAPEEVEMLYEEALYTVLYRAGTMGPDQVDDEEALLSYLQQVFGTSLEEHTEAIERVRKAKAPTYALKVSVMRAKNLLAKDPNGFSDPYCMLGILPASDATREPRAQKEQRFGFRKG----SKRGGP---LPAKCIQVTEVKSSTLNPVWKEHFLFEIEDVSTDQLHLDIWDHDDDVSLVEACRKLNEVIGLKGMGRYFKQIVKSARANG-TAGPTEDHTDDFLGCLNIPVREVPVAGVDRWFKLEPRSSASRVQGHCHLVLKLITTQRDTAMSQRGRSGFLSHLLLLSHLLRLEHSAEEPNSSSWRGELSTPAATILCLHGAQSNLSPLQLAVLHWQVSSRHHQTCTLDYSYLLGLLEDMQAHWEEAPSLPQEQEESLADSLSAFSEFGLQLLRQLRDYFPATNSTAVHRLELLLKCLGKLQLFQPSFEICPFESELNMDIAAALKRGNREWYDRILNDKSPREQPGPQRLPGLVVLADAVYDDLQFCYSVYASLFHSILNVDVFTLTFRQLERLVAEEAWVLTEELS-------PKMTLEVASGLFELYLTLADLQRFWDSIPGRDSRSLALAGIHAPFLPAVKLWFQVLRDQAKWRLQGAVDMDTLEPVDASSRHSSSAATAGLCLSHIQELWVRLAWPDPAQAQGLGTQLGQDVCEATLFYTELLRKKVD-TQPGAAGEAVSEALCVVLNNVELVRKAAGQALKGLAWP------EGATGPEG--VLPRPLLSCTQALDDDLQREAHTVTAHLTSKMVGDIRKYVQHISLSPDSIQNDEAVAPLMKYLDEKLALLNASLVKGNLSRVLEALWELLLQAILQALGANRDVSADFYSRFHFTLEALVSFFHAEGQGLPLESLRDGSYKRLKEELRLHKCSTRECIEQFYLDKLKQ-RTLEQNRFGRLSVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVKTRTLHPVYDELFYFSVPAEACRRRAACVLFTVMDHDWLSTNDFAGEAALGLGGVTGVARPQVGGGARAGQPVTLHLCRPRAQVRSALRRLEGRTS-KEAQEFVKKLKELEKCMEADP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80TT2-2", "uniprot_id": "BAIP3_MOUSE", "id": "Q80TT2-2", "name": "BAI1-associated protein 3", "aln": "-----------------------------------MSTLLDIKSSVLRQVQVCPSFRRKTEQEP--EVTNSQEPPTGAWKPG--------DGVEFFAHMRLILKKGDGRQGLPCPEVLLRSGSPAPAEPVDPNRGLRTLTQEEVEMLYEEALYTVLHRAGTMGPDQVDDEEVLLSYLQQVFGTSSEEHMEAIMRVKKAKAPTYALKVSVMRAKNLLAKDPNGFSDPYCMLGILPASSAPQEPSGQKEQRFGFRKG----SKRSSP---LPAKCIQVTEVKNSTLNPVWKEHFLFEIDDVNTDQLHLDIWDHDDDVSLAEACRKLNEVIGLKGMTRYFKQIVKSARANG-TAGPTEDHTDDFLGCLNIPIREVPVAGADRWFKLEPRSSASRVQGDCHLVLKLITTQRDTVMSQRGRSGFLSYLLLLSRVLRFEHRVEEPNSSSWRGELSGPGTTVLCLHGAQSNLSPLQLAVLHWQVSSRHHQTRTLDYGYLLGLLEDVQAHWEEAASLPQEQEESLADSFSAFSEFGLRLLRQLRDYFPATNSTAVYRLELLLKCLEKLQLFQPAFEICPFETELSMDIAAALKRGNREWYDQLLNTKSPREQPGPQRLAGLVELADIIYEDLQLCYGVYASLFHGILKVDFFTLTFRQLERLVAEEAWVLTEELS-------PKMNLEVASGLFELYLTLADTQRFWSCIPGRESRSLALAGIHTPFLPAVKLWLQVLRDQAKWRLQGAVDVDTLEPVDAASKHSSSAATASLCLSHIQELWVRLAWPDPSQAQGLGTQLSQDMCEASLFYTELLRKKVD-TQPGAAGEAVSEQLCVVLNNVELVRRASGQALRGLAWS------EGASGLEG--VLPRPLLSCIQALDEDLHREAHTVTAHLTSKMVADIRKYIQHISLSPDSIQNDEAVAPLLKYLDEKLALLNDALVKENLNRVLEALWELLLQAILQALSANRDVSADFYGRFHFTLEALVSFFHAEGQGLPLENLRDGSYKRLQEELRLHKCSTRECIEQFYLDKLKQ-RSLEQNRFGRLTVRCHYEAAEQRLAVEVLHAADLLPLDANGLSDPFVIVELGPPHLFPLVRSQRTQVKARTLHPVYDELFHFSVPAEACRRRGACVLFTVMDHDWLSTNDFAGEAALGLGGISGIARPHVGGGMRPGQPITLHLRRPRAQVRSALRMLEGRTS-REAQEFVKKLKELEKCMEADL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "X1WGN8-1", "uniprot_id": "X1WGN8_DANRE", "id": "X1WGN8-1", "name": "", "aln": "-----------------------------------MSTLLDLKSSVLRQVQRSQSLR--TRREPPASTSAGGSPPTLARRSGTIVHRVARGNGDFFDRMNKILQKQDS-LLSACQTEEESSCALPPPECKDQAFVPEKSTRDELDLLYEEAIYTVVNRVGVPSPEYVTNEGDIFSYLQKVFDMGQEEHEIILQRVRESKKASFSLRVSVMKGKNLMAKDANGYSDPYCMLGILLG-QSPKDTEEKKERKFSFRKRREKLEKRSSVKEVLAGRDIQVTEVKPETLNPVWNEHFVFDIDDVHNDLLHLDIWDHDDDVSVAEACKKLNEISGFRGMGRYFKQIAKSVRANGATASGSEENADDFLGCINIPLNEIPVVGYDKWFKLEPRSSASKVQGECHLILRLFTTQRDTAMS-KMASNVTIHKKMLSQILDYEHNQIQKEPYNWNGQVCAAAWTVLSHHAVQADLSPLQQAIIRWQCYSSHHRSQRMSYALLLRLLKTVEAEWEDTAVQG-ELEGLLAESFRLYCDYCLSQMKSMRQVFPCNNSAAIIRCELMLRSVGHMQSMAAFRAVCSNRSELHLEIATVIKKGTVEWYEGIISNIKPDEGTLEEQLRRLVVVVDAVCADVQKGQNVYNKLYYSSVKVDFFSISYRQLEKLVADDVNVAMERVCGNLEQESSRLTQTMGETLFELYMSLKSLKRFREYLPLKDTKMLALTGFHNWFKTSIHKWLQIVHERSTERIRKAVEMDPLESIQSQSKHSSSAVDVTACFSQVREFWAQLAWPDSAGAFIFITRLTDNFCSEAVCYAELIKRKIERSQLGRDHKSFIVQVCVALNSTENVRVYLGGLPREMDWRGVEQAMEESCGLEGKEQVNKSLNGQLYNADIDLQREAKRLITHLTDRMIPELRRCIQHISLSPDSINNDEAVAPLMKYLDDTLVILNESLVKENLTRVLQSLWELLLRMILDAVGENRGVQVEFYTRFQYTVETLVRFFHADGEGLLLEDLKSGDYKGLDEELRLNKCSSFELIEQYFLEKISQQRILKHSRFGRISVKCYYDAPEQRLTVEILHAADLIALDANGLSDPFVIVELCPHHLFPTARSQRTQVKLKTLHPVFDELFYFHVSPEQYRHRCACLTFTVMDYDWLSTNDFAGEAVAPLSDFCWPGRPSATPAGKTLQPVILHLSRQKPSEKPIMKMLEARMGDREAQEFVRKLKEIEKSMEEE-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******:********* . *:* *.::* : .*.* * :.* .. :** :*. :*:* :. .* * : .*.* * . : :*:::*****:***: *.*. .*: * :* ::****:**. . *** : **:::* .:::*:****:.***:***.**:********** . .:.::. :**::*.*** .**.. *..: ******* .******:***:*:*:** .* *************:.***:****: *::** ******.**.**** **. :*:::******:***:.*:**.* *:***********:***.***:*:*:******.** : *.. : :**::* ** : :. .*.*::. .. *:*. *..*::***** *:::** * **:: :.*. ** **: ::*.**::. * * **:*: :.:: * ::.:*: **..**:*: * **:*:.: ::* : . :*. .:** ::**:.:*:*. ***: ::. .* * . ::* ** :.* : *:* .** .*::. ::**.*::::****:***::. * *.:. .::. :.. *****::* . :** . :* :::: ***:*:* * .::: *:*::::::. *:: **::*.**.::: *:*****. . *:*:::*:*.:*****.: * : *:* ::.*. :: *:**:::*:: :* * ::. :**.**..* ** * : : * * : * ** : :.* . * **:***: : :***.:*: ::*: :**********:********:****:.*.:** :*** **.***::******: **:*:. **.*..:** **::*:*:** ****:*:** **.*:.*.** *.*****:***: * ***::*:*:.* * *::.****::*:*:*:*.****:**:******:.*************** * **** .******** :*****:****:* *..* *:* **: *****:************. *... .** . . :. **: *** * :.. :. :: **.* . :******:****:**.** : ", "identical_positions": 536, "similar_positions": 381, "identity": "43.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-867", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P56857-1", "uniprot_id": "CLD18_MOUSE", "id": "P56857-1", "name": "Claudin-18", "aln": "MATTTCQVVGLLLSLLGLAGCIAATGMDMWSTQD-LYDNP--VTAVFQYEGLWRSCVQQSSGFTECRPYFTILGLPAMLQAVRALMIVGIVLGVIGILVSIFALKCIRIGSMDDSAKAKMTLTSGILFIISGICAIIGVSVFANMLVTNFWMSTANMYSGMGG------MGGMVQTVQTRYTFGAALFVGWVAGGLTLIGGVMMCIACRGLTPDDSNFKAVSYHASGQNVAYRPGGFKASTGFGSNTRNKKIYDGGARTEDDEQSHPTKYDYV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56856-1", "uniprot_id": "CLD18_HUMAN", "id": "P56856-1", "name": "Claudin-18", "aln": "MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQD-LYDNP--VTSVFQYEGLWRSCVRQSSGFTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFALKCIRIGSMEDSAKANMTLTSGIMFIVSGLCAIAGVSVFANMLVTNFWMSTANMYTGMG---------GMVQTVQTRYTFGAALFVGWVAGGLTLIGGVMMCIACRGLAPEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKNKKIYDGGARTEDEVQSYPSKHDYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40EBY6-1", "uniprot_id": "A0AB40EBY6_DANRE", "id": "A0AB40EBY6-1", "name": "Claudin", "aln": "MSAPALQTTGFVSGVIGTAGVFAATLMDVWCFRNQQQDQPQRVSSIYTYKGLWKDCEMSGTVFPECQPLYSHPNYSGILQAARALMIIAILVAVIAVFIGFFCLKCLKMKNMQLSTRAKLILSSAIIFFIAGICGIAAASVYADQLVPSFMMPQFNQKQGEKGGVQCANNVAAMDPSASRYTFGPALYIAWVGAALLILGGILMSIAYKRMQW------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::.: *...:: .::* ** :*** **:*. :: *:* *:::: *:***:.* ..: *.**:* :: . ..:***.*****:.*::..*.:::.:*.***::: .*: *::*:: *:*.*:*:::*:*.* ..**:*: **..* *. * * . ::. :*****.**::.**...* ::**::*.** : : ", "identical_positions": 71, "similar_positions": 93, "identity": "26.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-870", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y446-1", "uniprot_id": "PKP3_HUMAN", "id": "Q9Y446-1", "name": "Plakophilin-3", "aln": "----MQDGNFLLSALQPEAGVCSLALPSDLQLDRRGAEGPEAERLRAARVQEQVRARLLQLGQQP-RHNGAAEPEPEAETARGTSRGQYHTLQAGFSSRSQGLSGDKTSGFRPIAKPAYSPASWSSRSAVDLSCSRRLSSAHNGGSAFG-AAGYGGAQPTPPMPTRPVSFHERGGVGSRADYDTLSLRSLRLGPGGLDDRYSLVSEQLEPAATSTYRAFA--YERQASSSSSRAGGLDWPEATEVSPSRTIRAPAVRTLQRFQSSHRSRGVGGAVPGAVLEPVARAPSVRSLSLSLADSGH-LPDV-HGFNSYG--SHRTLQRLSSGFDDIDLPSAVKYLMASDPNLQVLGAAYIQHKCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQRHATGAMRNLIYDNADNKLALVEENGIFELLRTLREQDDELRKNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAEIFYNATGFLRNLSSASQATRQKMRECHGLVDALVTSINHALDAGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRGRRDLAGAPPGEVVGCFTPQSRRLRELPLAADALTFAEVSKDPKGLEWLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALEQERILNPLLDRVRTADHHQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKSPPAEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLIFIKKKRD-SPDSEKSSRAASSLLANLWQYNKLHRDFRAKGYRKEDFLGP--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QY23-1", "uniprot_id": "PKP3_MOUSE", "id": "Q9QY23-1", "name": "Plakophilin-3", "aln": "----MQEGNFLLSALQPETGVCSLALPSDLQLDRRGAEGPEADRLRAARVQEQVRARLLQLGQQS-RHNGSAELDGSAESARGMPRGQYHTMQTGFSSRSQGMSGDKTSTFRPIAKPAYSPASWSSRSAVDLTCSRRLSSAHNGGSAFG-AVGYGGTQPTPPMPTRPVSFHERGGAASRADYDTLSLRSLRLGPGGLDDRYSVVSEQLEPAAASTYRAYA--YERQASSGSSRAGGLDWPEATEGPPSRTIRAPAMRTLQRFQSSHRSRGGTGSVSGAGLEPVARAPSVRSLSLSLADSGH-LPDV-RGLDSYT--GHRTLQRLSSGFDDIDLPSAVKYLMASDPNLQVLGAAYIQHRCYSDAAAKKQARSLQAVPRLVKLFNHANQEVQRHATGAMRNLIYDNVDNKLALVEENGIFELLRTLREQDDELRKNVTGILWNLSSSDHLKDRLARDTLEQLTDLVLSPLSGAGGPPLIQQNASEAEIFYNATGFLRNLSSASQATRQKMRECHGLVDALVTYINHALDVGKCEDKSVENAVCVLRNLSYRLYDEMPPSALQRLEGRGRRDMAGAPPGEMVGCFTPQSRRLRELPLTADALTFAEVSKDPKGLEWLWSPQIVGLYNRLLQRCELNRHTTEAAAGALQNITAGDRRWAGVLSRLALEQERILNPLLDRVRTADHNQLRSLTGLIRNLSRNARNKDEMSTKVVSHLIEKLPGSVGEKCPPAEVLVNIIAVLNNLVVASPIAARDLLYFDGLRKLVFIKKKRD-SPDSEKSSRAASSLLANLWQYSKLHRDFRAKGYRKEDFLGP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QWE6-1", "uniprot_id": "F1QWE6_DANRE", "id": "F1QWE6-1", "name": "", "aln": "MSAVAATEGLFFSALQPNTSVTTYAIPTDDHRRR-------DQLSKVRRVQQQVQQRMAEKSTSSSRLNASTEFNGHSPTVA------YQTRSPGFSSKSMIYNGNRTMAVPRLSQYAG---DFSSRSAVETGTRHRISLGVPMPAVVGRPYTYHDDAHLSSSYNQMQTSESRTLSRTEQEVAAMAGLTLQRQPSPVGNWMPNYGQSPSPNTAHRQRTLSGTLAREGFNTGWREAELANQYAFKGPSHRTISRINNRQVQQQQHQRLSGSSMQWQQMSTGGNSLMGAGHYQGTIKRAGSVHSMKSVGRGVDVYDGLADGTADGLG-GIHNLDMTTAVSYLSSTDVSMQMLGAAYVQHQCYHSNEAKTMVRSLKGISALVQLFSSENQEVQRYATGATRNLIYENMDNKTALIEAGGISKLIGALREPDDELRKNITGILWNLSSKDSLKERLARESLAELTERVLVPLSGGGDAGVIQQSASEADIFFNTTGCLRNLSSVNERTRQQMRETRGLVDSLVGYIQNSLQEGKGENKGVENCVCVLRNLSYQLYSEIPSSVQMRLEGPTR--AQDTRHSDAIGCFTPQSKKAKDR--NQDLTTFTEVARVPKGAEWLWHPQIVSLYNQILQSCEANTATREAAAGALQNITAGDSRWASVLSRVALEQERMLPVILDLLRSPTDAELRSLTGLLRNLSRHCKNKADMATKVVNVLVNKLPSDGHQKEPSSEVVVNICGVLNNLVTGSSLAARDITYFDGLPKLVSIKSSHDNSPGKLKAARAASTVLSNMFQYNKLHRDYKQKGFARRDFTDGII", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:::*****::.* : *:*:* : * : :. ***:**: *: : . .. * *.::* : : :. *:* ..****:* .*::* . ::: * .:******: :*:* . :..* . * . .. .: : ..* :. : ::: :*: *. :.: . .:. .* :: *: : *:. . . * . * * : .. *** * :*: * .: * . : ... . ::. *.* * : .* :*.: * .. * : *. *:.::*:.:**.** ::* .:*:*****:**:** . **. .***:.:. **:**. ******:**** *****:* *** **:* .** :*: :*** *******:*********.* **:****::* :**: ** ****.*.. :***.****:**:*:** ******..: ***:*** :****:** *:::*: ** *:*.***.*********:**.*:*.*. **** * .: .: :*******:: :: * **:**:: *** **** ****.***::** ** * * ************** ***.****:******:* :** :*:. . :*******:*****:.:** :*:****. *::***.. :* *.:**:*** .******..*.:****: ***** **: **..:* **.. *::****::*:*::**.*****:: **: :.** . ", "identical_positions": 342, "similar_positions": 238, "identity": "42.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-871", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZD37-1", "uniprot_id": "D3ZD37_RAT", "id": "D3ZD37-1", "name": "Rho-related BTB domain-containing protein 1", "aln": "MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDEVSISLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKTMWYQEIKHFCPRTPVVLVGCQLDLRYADLEAVNR----ARRPLARPIKRGDILPPEKGREVAKELGIPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPPPVIKVPECPSTGTSDAACLLDNPLCADVLFILHDQEHIFAHRIYLATSSSKFYDLFLMECEDSPGWSGGAG-EEVPCRDFQGRTQSLGAAEEGQEGSQRTPQADPGASSGQDLLESLASQTDASVSEAHALTGWSKGFVSMHREVRVNPISKRVGPVTVVRLDSSMQSGPFRTLLRFLYSGQLDEKEKDLLGLAQMAEVLEMFDLRMMVENIMNKEAFMNQEITKAFHVR-KANRIKECLSKGTFSDVTFTLDDGAISAHKPLLICSCEWMAAMFGGSFVESTNSEVHLPNINKMSMQAVLEYLYTKQLSPNLDLDPLELIALANRFCLTHLVALVEQHAVQELTKAAVSGV-SIDGEVLSYLELAQFHNANQLAAWCLHHICTNYNSVCSKFRKEIKSKSADNQEYFERHRWPPVWYLKEEDHYQRVKREREKE------------------------------------------------------------------DLALNKHHSRRK--------------WCFWHPSPAVA-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAK3-1", "uniprot_id": "RHBT1_MOUSE", "id": "Q9DAK3-1", "name": "Rho-related BTB domain-containing protein 1", "aln": "MDSDMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDEVSISLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKTMWYQEIKHFCPRTPVVLVGCQLDLRYADLEAVNR----ARRPLARPIKRGDILPPEKGREVAKELGIPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPPPVIKVPECPSAGTSDAACLLDNPLCADVLFVLHDEEHIFAHRIYLATSSSKFYDLFLMECEESPCWGGGAG-EEVPCRDFQGRTQSLGSAEEGKEGPQRTPQADPGASSGQDLPESLALQMEASGSEGHALSGWSKGFVSMHREVRVNPISKRVGPVTVVRLDPSMQSGPFRTLLRFLYSGQLDEKEKDLLGLAQMAEVLEMFDLRMMVENIMNKEAFMNQEITKAFHVR-KANRIKECLSKGTFSDVTFTLDDGAISAHKPLLICSCEWMAAMFGGSFVESANREVHLPNINKMSMQAVLEYLYTKQLSPNLDLDPLELIALANRFCLTHLVALVEQHAVQELTKAAVSGV-SIDGEVLSYLELAQFHNANQLAAWCLHHICTNYNSVCSKFRKEIKSKSADNQEYFERHRWPPVWYLKEEDHYQRVKREREKE------------------------------------------------------------------DLALNKHHSRRK--------------WCFWHSSPAVA-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94844-1", "uniprot_id": "RHBT1_HUMAN", "id": "O94844-1", "name": "Rho-related BTB domain-containing protein 1", "aln": "MDADMDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDEVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLNHVKSMWYPEIKHFCPRTPVILVGCQLDLRYADLEAVNR----ARRPLARPIKRGDILPPEKGREVAKELGLPYYETSVFDQFGIKDVFDNAIRAALISRRHLQFWKSHLKKVQKPLLQAPFLPPKAPPPVIKIPECPSMGTNEAACLLDNPLCADVLFILQDQEHIFAHRIYLATSSSKFYDLFLMECEESPNGSEGACEKEKQSRDFQGRILSVDPEEEREEGPPRIPQADQWKSSNKSLVEALGLEAEGAVPETQTLTGWSKGFIGMHREMQVNPISKRMGPMTVVRMDASVQPGPFRTLLQFLYTGQLDEKEKDLVGLAQIAEVLEMFDLRMMVENIMNKEAFMNQEITKAFHVR-KANRIKECLSKGTFSDVTFKLDDGAISAHKPLLICSCEWMAAMFGGSFVESANSEVYLPNINKISMQAVLDYLYTKQLSPNLDLDPLELIALANRFCLPHLVALAEQHAVQELTKAATSGV-GIDGEVLSYLELAQFHNAHQLAAWCLHHICTNYNSVCSKFRKEIKSKSADNQEYFERHRWPPVWYLKEEDHYQRVKREREKE------------------------------------------------------------------DIALNKHRSRRK--------------WCFWNSSPAVA-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RSW5-1", "uniprot_id": "A0A8M1RSW5_DANRE", "id": "A0A8M1RSW5-1", "name": "Rho-related BTB domain-containing protein 1", "aln": "----MDYERPNVETIKCVVVGDNAVGKTRLICARACNTTLTQYQLLATHVPTVWAIDQYRVCQEVLERSRDVVDDVSVSLRLWDTFGDHHKDRRFAYGRSDVVVLCFSIANPNSLHHVKTMWYLEIKHFCPRTPVILVGCQLDLRYADLEAVNR----ARRPLSRPIKPGDILPPESGREVAKELGIPYYETSVFDQFGIKDIFDNAIRAALISRRHLQFWKSHLRRVQKPLLQAPFLPPKAPPPLIKIPECPAKNRDGPKQLLETPLCADVMFIVQEHVHLYAHRIYLSTSSSKFFDLFQMDFSDE---SQCLVVTERHGRDQLMRTLSLDTEEDVMVLPNLSP-CSLRASKSDGTLKMLSFSGMHRRTR-LSLASWSKAFYSIHKENVINPVTGTPALMTIVKMDHSIHHGPFSAVLRFLYTGELDEKEKDLMKIAQIAEILEVFDLRMMVENIMNNEGFMNQEITKAFHVR-KANRIKECLAKNNFTDVVFRLDDGTINAHKPLLISSCDWMAALFGGSFMESANDEVSFPNTSRVCMQAVLEYLYTNQLSPMADLDPMELIALANRLCLPRLIALTEQYAVSELLKASKDGQ-DIDGEVLTYLELAQFHNANQLAAWCLHHICTHYNRICANYRKEIKSKSPENQEYFEKHRWPPVWYLKEEDHYQRVKKEREKE------------------------------------------------------------------DVVLNKHHSRRR--------------WCFWSTSPAVA-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PG08-1", "uniprot_id": "M9PG08_DROME", "id": "M9PG08-1", "name": "", "aln": "-MPKMDNEQPHQELVKCVLVGDTAVGKTRLICARACNKHVSLSQLLSTHVPTVWAIDQYRIYKDVLERSWEVVDGVNVSLRLWDTFGDHDKDRRFAYGRSDVVLLCFSIASPISLRNCKMMWYPEIRRFCPDVPVILVGCKNDLRYMYRDENYLSYFGEKGTFVRAALKSDLVMPDEARAVAKELGVAYYETSVFTYFGVNEVFENAIRSALIARRQQRFWMTNLKKVQKPLLQAPFRPPKPPPPEVTVMVG--NYRQDIYNMFLSQAYTDLVLVGAGGTKFAVHRFMLAAASSIFQRLLSTELTDMGGRSSSES-SMVSSTFGEATIADFNDDTEALIRYESRTQRMWEHLKRRSSYQALPLMESKRSND--LYRELHHPVLQSIRLVHVENHRGVNGLQTIVTLSKLISPQALHQCLRFIYTGTIDKDCDNIEEIREAADLLELPQLTQLLSRPQTVMENSSDEPNPHICLRIKESMERHCIGDGCFSDVTFELDDGLMKAHRAVLVGRCDVMRAMLLGDFREAHSNVIVFPGVTIYTFHKLLCYLYTDQIPPISAVKCLNLLELANRLCLPRLLNLVECRVIEDLTLISQNETNETVDHCLKLLEPVKLHNAHQLAEWCMSYLCVNYNLICKFSLKGLKALHQDNQEYLREHRWPPVWYLKDYDYYQRCLNELNKELKLKTSRRESPSDDEGCLCFTGVFSCWLLGKSKRSADVSGTTDNSNADNQIFNSAGNSLNHIDLEADMDLNLXHPALGQGRSLRFIVILPVLICFICTILSILILFQIHT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** *:*: * :***:***.**************. :: ***:*************: ::***** :*** *.:***********.*************:******.* **.: * *** **::*** .**:****: **** : : .: *. .*:: *:..* ******:.******* **::::*:****:***:**: :** ::*::********** ***.*** :.: . :: . :*:::: :: .**: *:::** * *: : : . ... : . . . : * : . : :: . *:* :. : .: *:*:*:* :*:. .:: : : *::**: :* ::.. . .:* . : :* * . :.*:... *:**.* **** :.**:.:*: *: * *:: *.* *: . : :*. . :: :* ****.*:.* :. ::*: ****:**.:*: *.* .:.:* : . .. *. ** .::***:*** **: ::*.:** :* * :*: :****:..**********: *:*** .* :** *: ** :. ** . :: ", "identical_positions": 253, "similar_positions": 196, "identity": "32.07%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-873", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15384-1", "uniprot_id": "KCNA3_RAT", "id": "P15384-1", "name": "Potassium voltage-gated channel subfamily A member 3", "aln": "----------------------------------------------------MTVVPGDHLLEPEAAGGGGGDPPQGGCVSG--------GGCDRYEPLPPALPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASPSQDVFEAANNSTSGASSGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAE--------------RQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPSSGFNSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQA--QYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGM--------------------------------------------------------------------------NHSAFPQTPFKTGNSTATCTTNNNPNSCVNIKK-------IFTDV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16390-1", "uniprot_id": "KCNA3_MOUSE", "id": "P16390-1", "name": "Potassium voltage-gated channel subfamily A member 3", "aln": "----------------------------------------------------MTVVPGDHLLEPEAAGGGGGDPPQGGCGSGGGG-----GGCDRYEPLPPALPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASPSQDVFEAANNSTSGAPSGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAE--------------RQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPSSGFNSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQA--QYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGM--------------------------------------------------------------------------NHSAFPQTPFKTGNSTATCTTNNNPNSCVNIKK-------IFTDV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22001-1", "uniprot_id": "KCNA3_HUMAN", "id": "P22001-1", "name": "Potassium voltage-gated channel subfamily A member 3", "aln": "MDERLSLLRSPPPPSARHRAHPPQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDHLLEPEVADGGG-APPQGGCGGG---------GCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLKTLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVETLCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAE--------------RQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQS--QYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGM--------------------------------------------------------------------------NHSAFPQTPFKTGNSTATCTTNNNPNSCVNIKK-------IFTDV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q783-1", "uniprot_id": "A0A8M9Q783_DANRE", "id": "A0A8M9Q783-1", "name": "", "aln": "MDDHYNLIDSPSASHR---------------GNNADNHGYAETEK-----DIMTVVACDNMLEETAA-----LPSH--------------LSLDRYEP---------DHECC-ERVVINISGLRFETQLKTFNQFPDTLLGDPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIFSEEIRFYQLGEEAMEKFREDEGFIKEEERPLPDHEFQRQVWLLFEYPESSGPARGIAIVSVLVILISIVIFCLETLPEFRDDKD-PTTVS-----PIANVTG--PFVSSTFTDPFFVIETLCIIWFSFELLVRFFACPSKATFSKNIMNIIDIVAIIPYFITLGTELAE--------------RQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEADDPTSSFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDGEEHA--QYLHVGSCQHLN-STEDLKRTQSTSSLSKSEYMVIEEG----------------------------------------------------------------------------INSAFKQPNYS----------NQNNQNCVNIKK-------IFTDV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08510-1", "uniprot_id": "KCNAS_DROME", "id": "P08510-1", "name": "Potassium voltage-gated channel protein Shaker", "aln": "MAAVAGLYGLGEDRQHRKKQQ----------QQQQHQKEQLEQKEEQKKIAERKLQLREQQLQRNSLDGYGSLPKLSSQDEEGGAGHGFGGGPQHFEPIP------HDHDFC-ERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTN---------GTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQEEMQSQNFNHVTSCPYLPGTLGQHMKKSSLSESS-SDMMDLDDGVESTPGLTETHPGRSAVAPFLGAQQQQQQPVASSLSMSIDKQLQHPLQQLTQTQLYQQQQQQQQQQQNGFKQQQQQTQQQLQQQQSHTINASAAAATSGSGSSGLTMRHNNALAVSIETDV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :: *: * . :::** ::: * ******:*********:*: ***:****** :*:**************.****************:*******:*:*****:**:**::*::********::******* .: **:*********** .** :**:**:***:*************:. * :: . * . ::****::********:*** ***:***.* .*.:::**:***:*********.* :** :: ..:*********************************:********************:***********.. .* *.********************* ** : ***********************************: ** :: ** ** :* : : : * * * *: * :::* :. : * . . .. :.::: * ***", "identical_positions": 313, "similar_positions": 95, "identity": "45.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-875", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5T848-1", "uniprot_id": "MGLYR_HUMAN", "id": "Q5T848-1", "name": "Metabotropic glycine receptor", "aln": "------MGAMAYPLLLCLLLAQLGLG--AVGASRDPQGRPDSPRERTPKGKPHAQQPGRASASDSSAPWSRSTDGTILAQKLAEEVPMDVASYLYTGDSHQLKRANCSGRYELAGLPGKWPALASAHPSLHRALDTLTHATNFLNVMLQSNKSREQNLQDDLDWYQALVWSLLEGEPSISRAAITFSTDSLSAPAPQVFLQATREESRILLQDLSSSAPH-LANATLETEWFHGLRRKWRPHLHRRGPNQGPRGLGHSWRRKDGLGGDKSHFKWSPPYLECENGSYKPGWLVTLSSAIYGLQPNLVPEFRGVMKVDINLQKVDIDQCSSDGWFSGTHKCHLNNSECMPIKGLGFVLGAYECICKAGFYHPGVLPVNNFRRRGPDQHISGSTKDVSEEAYVCLPCREGCPFCADDSPCFVQEDKYLRLAIISFQALCMLLDFVSMLVVYHFRKAKSIRASGLILLETILFGSLLLYFPVVILYFEPSTFRCILLRWARLLGFATVYGTVTLKLHRVLKVFLSRTAQRIPYMTGGRVMRMLAVILLVVFWFLIGWTSSVCQNLEKQISLIGQGKTSDHLIFNMCLIDRWDYMTAVAEFLFLLWGVYLCYAVRTVPSAFHEPRYMAVAVHNELIISAIFHTIRFVLASRLQSDWMLMLYFAHTHLTVTVTIGLLLIPKFSHSSNNPRDDIATEAYEDELDMGRSGSYLNSSINSAWSEHSLDPEDIRDELKKLYAQLEIYKRKKMITNNPHLQKKRCSKKGLGRSIMRRITEIPETVSRQCSKEDKEGADHGTAKGTALIRKNPPESSGNTGKSKEETLKNRVFSLKKSHSTYDHVRDQTEESSSLPTESQEEETTENSTLESLSGKKLTQKLKED---SEAESTESVPLVCKSASAHNLSSEKKTGHPRTSMLQKSLSVIASAKEKTLGLAGKTQTAGVEERTKSQKPLPKDKETNRNHSNSDNTETKDPAPQNSNPAEEPRKPQKSGIMKQQRVNPTTANSDLNPGTTQMKDNFDIGEVCPWEVYDLTPGPVPSESKVQKHVSIVASEMEKNPTFSLKE--KSHHKPKAAEVCQQSNQKRIDKA-------------------EVCLWESQGQSILEDEKLLIS------KTPVLPERAK---------EENGGQPR----AANVCAGQSEE---------------------------LPPKAVASKTENENLNQIGHQEKKTSSS----------------EENVRGSYNSSNNFQQPLTS--RAEVCPWEFETPA--------QPNAGRSVALPASSALSANKIAGPRKEEIWDSFKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C419-1", "uniprot_id": "MGLYR_MOUSE", "id": "Q8C419-1", "name": "Metabotropic glycine receptor", "aln": "------MGAMAYSLLFCLLLAHLGLG--EVGASLDPPGRPDSPRERTPRGKQHGQQLPRASAPDPSIPWSRSTDGTILAQKLAEEVPVDVASYLYTGDFHQLKRANCSGRYELAGLPGKSPSLASSHPSLHGALDTLTHATNFLNMMLQSNKSREQTVQDDLQWYQALVRSLLEGEPSISRAAITFSTESLSTPAPQVFLQATREESRILLQDLSSSAHH-LANATLETEWFHGLRRKWRPHLHRRGSNQGPRGLGHSWRRRDGLGGDRSHVKWSPPYLECENGSYKPGWLVTLSAAFYGLQPNLVPEFRGVMKVDISLQKVDIDQCSSDGWFSGTHKCHLNNSECMPIKGLGFVLGAYQCICKAGFYHPRVFSVNNFQRRGPDHHFSGSTKDVSEETHVCLPCREGCPFCADDRPCFVQEDKYLRLAIISFQALCMLLDFVSMLVVYHFRKAKSIRASGLILLETILFGSLLLYFPVVILYFEPSTFRCILLRWARLLGFATVYGTVTLKLHRVLKVFLSRTAQRIPYMTGGRVMRMLAVIVLVVFWFLVGWTSSMCQNLERDILLVGQGQTSDHLTFNMCLIDRWDYMTAVAEFLFLLWGIYLCYAVRTVPSAFHEPRYMAVAVHNELIITAIFHTIRFVLASRLQPDWMLMLYFAHAHLTVTVTIGLLLIPKFSHSSNNPRDDIATEAYEDELDMGRSGSYLNSSINSAWSEHSLDPEDIRDELKKLYAQLEIYKRKKMITNNPHLQKKRCSKKGLGRSIMRRITEIPETVSRQCSKEDKEGTDHSAAKGTGLVRKNPTESSGNTGRPKEESLKNRVFSLKKSHSTYDHVRDQTVESSSLPMESQEEEATENSTLESLSSKKLTQKLKED---SEAESTESVPLVCKSASAHNLSSEKKPGHPRTSMLQKSLSVIASAKEKTLGLAGKTQTLVMEDRAKSQK--PKDRETIRKYSNSDNVETIP----NSGHMEEPRKPQKSGIMKQQRVSLPTANPDVSSGITQIKDNFDIGEVCPWEVYDLTPGPMPSEPKAQKHVSIAASEVEQNPASFLKE--KSYHKSKATEGLYQANHKSIDKT-------------------EVCPWEIHSQSLLEDENRLIS------KTPVLPGRAR---------EENGSQLY----TTNMCAGQYEE---------------------------LPHKVVAPKVENENLNQMGDQEKQTSSS----------------VDIIPGSCNSSNNSHQPLTS--RAEVCPWEFEPLE--------QPNAERSVTLPASSALSANKIPGPQK---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FGF1-1", "uniprot_id": "E7FGF1_DANRE", "id": "E7FGF1-1", "name": "", "aln": "MSMENVHGACWRRGMDAFLLYLLLLIGIAKGSNYGYVEWSESDKDLEIKAKYPVYS---TSETTHQQPTISSTERPAVAHKLEEDLPRVVTAFLHTGDSSTLEHVNCSRRYELSSLRGG--AHAASHSSLQGVLDTVAQATNFLNMLLQSNTSKEQHLRMDIQWYHALVSSMLEGNPKIHRAVVTFHMESPEAPGPQVFLQATRGEERIVLQDLSTTARHRLKNRTSESDWYNVFRDRNK---HKRLVKSRAFPAAH-----GGYFLDKSHVKWSSPYLECEHGRFVPHWLLTISAGFYGLKNKTAPEFRGVVRVDVNLQDVDIDQCSNSGWFAGTHRCNLTSMECNPIVGHGFVLDKYKCQCKRGFYHPSRVALNGFSKT----DLGTYTDESWELSGRCLPCREGCEFCRDDTPCLAHEDTALRLAMVSFQGFCMLLDFISMVVVYHFRHNKRIKASGLILLEAILSGSVLLYFPVMIQYLNPSVFRCILLRWVRLLGFAIVYGTVILKLYRVLKVFLSRTAQRIPYMTSWRVLRLLAVILLVVMWFLAAWTSAVCQNHNTRHALIDIGVTPEGLQFSMCLLDSWDYMMAAAEFLFLLWGVYLCYAVRTVPSAFHEPRYLAVAIYNELLISAIFHIIRFSLGTGLHPDWMLMLFFVHTHLTVTVTLGLLLIPKFLFTGTHAREDIATEAYEDELDMGHSGSCLNSSITSAWSEHSLDPEDIREELKKLYSQLEIYKRKKMLANNPHLQKKRSSKRGLGRTLMRRITEIPETVSRQYSREDRDGSDHGSNRST--LRRNPFDPS-HSGKSREESLKSKMFSLKRSHS-YDHTHDQGGQTNGVPGDKMENSTTEASLLDTLMGRRSNKKNPEVPKVELAESTESVPLVCKSASAHNLAAEKKPVHLRTSMLQKSLSVIASAREKTLGIAGKTHS--VEDANKKGL---KAREGTALSEVDESPECLP-KMIISQSVEYTKTPSKMGIMKQQ---VSGSQPSICSEPGKSKELYDLSEVCPWEVEDL---PTPSEGKSQKHVSIAPNETTTIHGSSAKSGHKSQHKQKGLGQSPSNRRRSRDKTGERDEGRKPKSPLNLTTHKDASAWNFEDSSLQAMDTAGLSPERISRKKSVTPTDGKPKIFLSDISKSTGSLLQPPALMVDICPWDFDPPLSPNQDKTSSPIHHSKRRDSSSKRKGLSSKEKAMKDKDDEKRSSKIKERRSSSSRTSEKRRTSQSSEGDQAAMVASSRRRSSTRDTAFSSSKRTEVCPWETEALSSVTSHDKDTPSTENHTTQTPPTYLNMADVCPWDYDEKSGKSA-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : .:** * * *:. . .:* :: :.* . :* . . * **: . :*:** *::* *:::*:*** *::.*** ****:.* * : *::*.**: .***:::******::****.*:** :: *::**:*** *:***:*.* **.:** :* .:*.********* *.**:*****::* * * * * *::*:: :* : : *:* :. . .* .* *:**.***.******:* : * **:*:*:.:***: : .******::**:.**.*******..***:***:*:*.. ** ** * ****. *:* ** ***** ..:*.* : .:. *.: * : ******** ** ** **:.:**. ****::***.:******:**:******: * *:********:** **:******:* *::**.********.****** ***** ***:******************. **:*:****:***:*** .***::*** : *:. * *.: * *.***:* **** *.*********:******************:***::***:*:**** *** *.: *:.******:*.*:*******:******** .:..:.*:**************:*** *****.**************:******:**********::*********.**:****::************** *:**::*:**.: :.* :*:** :.* ::*:.:**:**.::****:*** ***.:** ::..:* :. *:.:** * *::* .:: .:* * . *******************::***. * ***************:*****:****:: :*: *. * :* . .:. * * * .:.*.* ****** . ::..: . : *: :*:.******* ** * *** * ******...* *. ** ** *. . .:: **: :.. *: ...*: :. :* *..* * .: :..*. .::*. : : *. * * * :::: .. :*:::*** : .* . *.. . .::* *:****** *. *.: . .: ...: *. .: ", "identical_positions": 609, "similar_positions": 322, "identity": "46.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-876", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70587-1", "uniprot_id": "LRRC7_RAT", "id": "P70587-1", "name": "Leucine-rich repeat-containing protein 7", "aln": "--------------------------------------MTTKRKLIGRLVPCRCFRGEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSSLPTSIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFSELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIG------NLSLLEEFDCSCNELESLPPTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQRLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSKALIPLQTEAHPETKQRVLTNYMFPQQPRGDEDFQSDSDSFNPTLWEEQRQQRMTVAFEFEDKKEDDESAGKVKALSCQAPWDRGQRGITLQPARLSGDCCTPWARCDQQIQDMPVPQSDPQLAWGCISGLQQERSMCAPLPVAAQSTTLPSLSGRQVEINLKRYPTPYPEDLKNMVKSVQNLVGKPSHGVRVENANPTANTEQTVKEKFEHKWPVAPKEITVEDSFVHPANEMRIGELHPSLAETPLYPPKLVLLGKDKKESTDESEVDKTHCLNNSVSSGTYSDYSPSQASSASSNTRVKVGSLQPTTKDAVHNSLWGNRIAPPFPQPLDAKPLLTQREAVPPGNLPQRPDRLPMSDAFPDNWTDGSHYDNTGFVSEEATGENANN---NPLLSSKARSVP-AHGRRPLIRQERIVGVPLELEQS-----THRHTPETEVP-PSNPWQNWTRTPSPFEDRTAFPSKLETTPTTSPLPERKDHMKEPTETPGPFSPGVPWEYHDPTPN---RSLGNVFSQIHCRPDSSKG-VIAISKSTERLSPLMKDIKSNKFKKSQSIDEIDVGTYKVYNIPLENYASGSDHLGSHERPDKFLGPEHGMSSMSRSQSVPMLDDEMLMYGSSKGPPQQKASMTKKVYQFDQSFNPQGAVEV-KAEKRIPPPFAHNSEYVQQPGKNIAKDLVSPRAYRGYPPMEQMFSFSQPSVNEDAMVNAQFASQGPRAGFLRRADSLASSTEMAMFRRVSEPHELPPGDRYGRAA-YRGGLEGQSSVS-MTDPQFLKRNGRYEDEHPSYQEVKAQAGSFPAKNLTQRRPLSARSYSTESYGASQTRPVSARPTMAALLEKIPSDYNLGNYGDKTSDNSDIKTRPTPVKGEESCGKMPADWRQQLLRHIEARRLDR--------------------------------------------------TPSQQSNILDNGQEDVSPSGQWNPYPLGRRDVPPD--TITKKAGSH----IQTLMGSQS-LQHRSREQQPYEGNINKVTIQQFQSPLPIQIPSSQATRGPQPGRCLIQTKGQRSMDGYPEQFCVRIEKNPGLGFSISGGISGQGNPFKPSDKGIFVTRVQPDGPASNLLQPGDKILQANGHSFVHMEHEKAVLLLKSFQNTVDLVIQRELTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80TE7-1", "uniprot_id": "LRRC7_MOUSE", "id": "Q80TE7-1", "name": "Leucine-rich repeat-containing protein 7", "aln": "--------------------------------------MTTKRKLIGRLVPCRCFRGEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSSLPTSIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFSELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIG------NLSLLEEFDCSCNELESLPPTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQRLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSKALIPLQTEAHPETKQRVLTNYMFPQQPRGDEDFQSDSDSFNPTLWEEQRQQRMTVAFEFEDKKEDDESAGKVKALSCQAPWDRGQRGITLQPARLSGDCCTPWARCDQQIQDMPVPQSDPQLAWGCISGLQQERSMCAPLPVAAQSTTLPSLSGRQVEINLKRYPTPYPEDLKNMVKSVQNLVGKPSHGVRVENSNPTANTEQTVKEKFEHKWPVAPKEITVEDSFVHPANEMRIGELHPSLAETPLYPPKLVLLGKDKKESTDESEVDKTHCLNNSVSSGTYSDYSPSQASSASSNTRMKVGSLQATAKDAVHNSLWGNRIAPPFPQPLDAKPLLSQREAVPPGNIPQRPDRLPMSDAFPDNWTDGSHYDNTGFVSEEAAGENANN---NPLLSSKARSVP-AHGRRPLIRQERIVGVPLELEQS-----THRHTPETEVP-PSNPWQNWTRTPSPFEDRTAFPSKLETTPTTSPLPERKDHMKEPTETPGPFSPGVPWEYHDPTPN---RSLGNVFSQIHCRPDSSKG-VIAISKSTERLSPLMKDIKSNKFKKSQSIDEIDVGTYKVYNIPLENYASGSDHLGSHERPDKFLGPEHGMSSMSRSQSVPMLDDEMLMYGSSKGPPQQKASMTKKVYQFDQSFNPQGAVEV-KAEKRIPPPFAHNSEYVQQPSKNIAKDLVSPRAYRGYPPMEQMFSFSQPSVNEDAMVNAQFASQGPRAGFLRRADSLASSTEMAMFRRVSEPHELPPGDRYGRAT-YRGGLEGQSSIS-MTDPQFLKRNGRYEDEHPSYQEVKAQAGSFPAKNLTQRRPLSARSYSTESYGASQTRPVSARPTMAALLEKIPSDYNLGNYGDKTSDNSDIKTRPTPVKGEESCGKMPADWRQQLLRHIEARRLDR--------------------------------------------------TPSQQSNILDNGQEDVSPSGQWNPYPLGRRDVPPD--TITKKAGSH----IQTLMGSQS-LQHRSREQQPYEGNINKVTIQQFQSPLPIQIPSSQATRGPQPGRCLIQTKGQRSMDGYPEQFCVRIEKNPGLGFSISGGISGQGNPFKPSDKGIFVTRVQPDGPASNLLQPGDKILQANGHSFVHMEHEKAVLLLKSFQNTVDLVIQRELTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96NW7-4", "uniprot_id": "LRRC7_HUMAN", "id": "Q96NW7-4", "name": "Leucine-rich repeat-containing protein 7", "aln": "MMENLIRGRNPPQYQRSPCKEVRAALRKRPEEELQCLEMTTKRKIIGRLVPCRCFRGEEEIISVLDYSHCSLQQVPKEVFNFERTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIG------NLSLLEEFDCSCNELESLPSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLNLSDNRLKNLPFSFTKLKELAALWLSDNQSKALIPLQTEAHPETKQRVLTNYMFPQQPRGDEDFQSDSDSFNPTLWEEQRQQRMTVAFEFEDKKEDDENAGKVKDLSCQAPWERGQRGITLQPARLSGDCCTPWARCDQQIQDMPVPQNDPQLAWGCISGLQQERSMCTPLPVAAQSTTLPSLSGRQVEINLKRYPTPYPEDLKNMVKSVQNLVGKPSHGVRVENSNPTANTEQTVKEKYEHKWPVAPKEITVEDSFVHPANEMRIGELHPSLAETPLYPPKLVLLGKDKKESTDESEVDKTHCLNNSVSSGTYSDYSPSQASSGSSNTRVKVGSLQTTAKDAVHNSLWGNRIAPSFPQPLDSKPLLSQREAVPPGNIPQRPDRLPMSDTFTDNWTDGSHYDNTGFVAEETTAENANS---NPLLSSKSRSTS-SHGRRPLIRQDRIVGVPLELEQS-----THRHTPETEVP-PSNPWQNWTRTPSPFEDRTAFPSKLETTPTTSPLPERKEHIKESTEIPSPFSPGVPWEYHDSNPN---RSLSNVFSQIHCRPESSKG-VISISKSTERLSPLMKDIKSNKFKKSQSIDEIDIGTYKVYNIPLENYASGSDHLGSHERPDKMLGPEHGMSSMSRSQSVPMLDDEMLTYGSSKGPQQQKASMTKKVYQFDQSFNPQGSVEV-KAEKRIPPPFQHNPEYVQQASKNIAKDLISPRAYRGYPPMEQMFSFSQPSVNEDAVVNAQFASQGARAGFLRRADSLVSATEMAMFRRVNEPHELPPTDRYGRPP-YRGGLDRQSSVT-VTESQFLKRNGRYEDEHPSYQEVKAQAGSFPVKNLTQRRPLSARSYSTESYGASQTRPVSARPTMAALLEKIPSDYNLGNYGDKPSDNSDLKTRPTPVKGEESCGKMPADWRQQLLRHIEARRLDRNAAYKHNTVNLGMLPYGGISAMHAGRSMTLNLQTKSKFD---HQELPLQKTPSQQSNILDNGQEDVSPSGQWNPYPLGRRDVPPD--TITKKAGSH----IQTLMGSQS-LQHRSREQQPYEGNINKVTIQQFQSPLPIQIPSSQATRGPQPGRCLIQTKGQRSMDGYPEQFCVRIEKNPGLGFSISGGISGQGNPFKPSDKGIFVTRVQPDGPASNLLQPGDKILQANGHSFVHMEHEKAVLLLKSFQNTVDLVIQRELTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BDH3-1", "uniprot_id": "A0A8M2BDH3_DANRE", "id": "A0A8M2BDH3-1", "name": "Leucine-rich repeat-containing protein 7", "aln": "-------------------------MDNYSTLQLQCLEMTTKRKIIGRLVPCRCFRGEEEVISVLDYSHCSLQQVPKEIFSFERTLEELYLDANQIEELPKQLFNCQALKKLSMPDNDLSNLPTTIASLVNLKELDISKNGIQEFPDNIKCCKCLSVVEASVNPIAKLPEGFTQLLNLTQLFLNDAFLEYLPANFGRLSKLRILELRENHLKTMPKSIHRLSQLERLDLGSNEFSELPEVLEQIHSLKELWLDNNSLQTIPGSIGKLRQLRYLDLAKNRIESLDADISGCESLEDLLLSANMLQQLPDSIGKLKKLTTLKVDDNQLTSLPNTIGSAHGKFGLSLLEEFDCSCNELESLPPTIGYLHSLRTFAADENFLSDLPREIGNCRNVTVMSLRSNKLEFLPDEIGQMTKLRVLNLSDNRLKNLPFTFTKLKDLAALWLSDNQSKALIPLQTEAHPETKQRVLTNYMFPQQPRHDEDYQSDTDSFNPTLWEEQRQQRMTVAFEFEDKKEEEDNSGKVKVEINLKRY----------PTPYPEDLKNMVKSVQNLVGKTTHPLNTEKCSSGTNMELHSQDKYEPKWPIAPKEVT---------ERDVKDYSNQPMSDQGVILNSAIDIPKRKEDLTESSEISLHRVVPKPQQPENTSLAVSSSSCFCLIDSMGGSPNDIRISDMRPTLVEPPMYKPKVVLLGKEKKESTDESEPDKMHCLNNSGSSATYSDYSPSQGSSGSSNPPGNVGNLQTSGKEGSSQTHWTNRLAQSFPKPIETKPLLSQRETPPSSTLQQRGERRPLSDTF-DSWNDAPHYDNTGFVAEEMPLDTPSSSAGNPMLGSKPRSASTAHGRRPLMRQDRIVGVPLELDQTQQTFHTVRNTPDTEVPAPSNPWQNWTRTPSPFEDRTAFPSKLEITPANSPNPDRKDFEQEMGEIPGTFPSTGAWGFLDSTDSGTGRGHPNVYTHIQVGKEPNKGNTMVLSKSSERLSPMMKEVKA-KFKKSQSIDEIDTGSYKVYSIPMDSYSSSIENQGSVDRADFPIPLEQ---SMSRSQSAPMLDDDLDGYGLNKSSQQQKPAIPKKVYHFDQSFNPQGAMDVLKAERRVPPPFPNTPEYVNQPGKTLPKELVSPRGYRGYPQMEQVFSFAPNATDDSHNQQLSVQPQRSRPGFLRRADSLVSSTEMALFRRVAENHELQLAEHYSRPQQIKSMLEQQNSLSTMADTQFHKRNGRYDEDYSSYQEPKKPIMGYPTKSLTQRRPLSARSYSTETYGASQARPVSARPTMAALLEKLPSDYNLSTCTEKSPE-ADMNLRPVPQKQEDLTSKMPVDWRQQLLRHIEAKRLDRSAVLKHNTVNFGMLYSGGYAAPHASRSMTINFYNNTKHENQTTQWLPLPNTPSQQSNILDNGQEVMSPSSQWAPYSLGRRDVPPENMNIIKKPGVHNPHQQQTMMITSAPPPHRTARDQQYEGAINKVSIQQYQSPLPMPITTTSPR--PQSARCFIQTKGQKSMDGFPEQLCVRIEKNPGLGFSISGGISGQGNPFKPSDMGIFVTRVQPDGPASNVLRPGDKILKANGHSFLHMEHETAVSLLKNFPKTVDLVILRESTI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V780-1", "uniprot_id": "LAP1_DROME", "id": "Q9V780-1", "name": "Protein lap1", "aln": "------------------------------------------MPLLSKCFPCFKFK-REEVIDKLDYSNTPLTDFP-EVWQHERTLEELYLSTTRLQALPPQLFYCQGLRVLHVNSNNLESIPQAIGSLRQLQHLDLNRNLIVNVPEEIKSCKHLTHLDLSCNSLQRLPDAITSLISLQELLLNETYLEFLPANFGRLVNLRILELRLNNLMTLPKSMVRLINLQRLDIGGNEFTELPEVVGELKSLRELWIDFNQIRRVSANIGKLRDLQHFEANGNLLDTLPSELSNWRNVEVLSICSNSLEAFPFSVGMLKSLVTFKCESNGLTELPDSIS------YLEQLEELVLSHNKLIRLPSTIGMLRSLRFLFADDNQLRQLPDELCSCQQLSVLSVANNQLSALPQNIGNLSKMKVLNVVNNYINALPVSMLNLVNLTSMWLSDNQSQPLVPLQYLDASTKTQ--LTCFMLPQVT------------FKMNSIQAQQQAQEQYEFVYANQQQPHAS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PSRRICFAEEATILSNAKAQPAPNYP------------------------------------------------------------------------------------------------------------------------------------------SFVAAPPTPTPDQMAGSVRLMRSPTPYPKELRQMSKYVRQAQAATSSANASEVREARVVTN--------------------------GQIHCDSNNANQDVVDQATTSAIYG--------------------------------------------------------------------IAPETTHIYGVYQQPQQMAHPVPTQEYYGLPLVNYEAHYQQLYVEANTPLPTTHLNG-------------------------DQDYELQPLQQQPMQQQALPTPRLEPPPYHIARVYTKKTPEDLNLYESMRQ---------------------------------------------------RKQQQQLQEQTIYQDALNSNSNFKTTAIGAQDVEES---------VDQLDYQNNISNNLEPNPEEEDQELDDT---------------------------------------------------------------------------------MSQHSLNSTATNNTSKASHKKSTWIFG--------------------------------------------------------------------------------------VHKNPTVKQVTLKWENSIGFDIAELLN---------QVGIFVSSITPNTNAARLLNLNDKLLEIDGYDLTNANLSDAKRVLLNCGTVMNIMLSRK---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.: .** *: .**:*. ****: .* :.* *::..*********.:.::: ** *** **.*: * : .*:*..:* :*.** :*:.**:.:* : :.*::**.** *: :: * *.: :**:.:*.*:.* :* **:::**:******** :******* *:* *:***: :* :*:***:*.*** *****: :::.*:***:* * :: :...****: * ::: * :::: ::*. . :* * :.:* *: :* *:* **.*.*:* :.* ** **::*. *. ***: * *:* **.*** *:*** : .*:* * :** *: .*::::*:*: .*:*. **::**:: :::***: :* :: **.:: :* :*:::*******:.*:*** . ..* ** :*:** . *: . : *:* : * : :::: . . .: *: :. : : :. .*: . : :* * .* . *:*:*: .. ** . :. . . . :* .. :*: : : .: :.:: . : : ** : . * .:..: * .* :. : .* . * * : :* :.: : . . .: *. : :. :: ::. : : : :.: * * .:.* : **.:.. :::: : *:.. : .: * : . **:* :: ..* : .: :* :. * * :: : .:**.*: :. : ****: : *: *:.:*. .**:*: :*:.: : : . * :* . ..::::: *: ", "identical_positions": 238, "similar_positions": 321, "identity": "14.8%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-880", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A229-1", "uniprot_id": "D4A229_RAT", "id": "D4A229-1", "name": "Serine/threonine-protein kinase", "aln": "MSAN-NSPPSAQKSVFPATVSAVLPTPSPCSSPKTGLSARLSNGSFSAASLTNSRGSVHTVSFLLQIGLTRESVTIEAQELSLSAVKDLVCSIVYQKFPECGFFGMYDKILLFRHNMNSENILQLITSADEIHEGDLVEVVLSA----LATVEDFQIRPHALYVHSYKAPTFCDYCGEMLWGLVRQGLKCEGCGLNYHKRCAFKIPNNCSGVRKRR-LSNVSLPGPGLSVPRPLQPECVPLLSEESHTHQEPSKRIPSWSGRP-IWMEKMVMCRVKVPHTFAVHSYGRPTICQYCKRLLKGLFRQGLQCKDCKFNCHKRCASKVPRDCLGEVTFNGEPSSVGT---DTDMPMDIDSNDVNSDGSRGLDDSEEPS--------PPEDKMFFLDAADLDVE------------------------RDEEPVKTISPSTSNNIPLMRVVQSIKHTKRKSSTVVKEGWMVHYTSRDNLRKRHYWRLDSKCLTLFQNESGSKYYKEIPLSEILRISSPQDFTSISQGSNPHCFEIITDTVVYFVGEN--NGN---STHNPVLAATGVGLDVAQSWEKAIRQALMPV--TPQASVCTSPGQGKDHKDLATSISVSNCQIQENVDISSVYQIFADEVLGSGQFGIVYGGKHRKTGRDVAIKVIDKMRFPTKQESQLRNEVAILQNLHHPGIVNLECMFETPERVFVVMEKLHGDMLEMILSSEKSRLPERITKFMVTQILVALRNLHFKNIVHCDLKPENVLLASAEPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRSKGYNRSLDMWSVGVIVYVSLSGTFPFNEDEDINDQIQNAAFMYPPNPWREISSEAIDLINNLLQVKMRKRYSVDKSLSHPWLQDYQTWLDLREFETRIGE-RYITHESDDARWEIHAYTHN-------LEYPKHFIMAPN-------------------PDDMEEGP----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K1Y2-1", "uniprot_id": "KPCD3_MOUSE", "id": "Q8K1Y2-1", "name": "Serine/threonine-protein kinase D3", "aln": "MSAN-NSPPSAQKSVFPATVSAVLPAPSPCSSPKTGLSARLSNGSFSAPSLTNSRGSVHTVSFLLQIGLTRESVTIEAQELSLSAVKDLVCSIVYQKFPECGFFGMYDKILLFRHDMNSENILQLITSADEIHEGDLVEVVLSA----LATVEDFQIRPHALYVHSYKAPTFCDYCGEMLWGLVRQGLKCEGCGLNYHKRCAFKIPNNCSGVRKRR-LSNVSLPGPGLSVPRPLQPECVPLLSEESHTHQEPSKRIPSWSGRP-IWMEKMVMCRVKVPHTFAVHSYGRPTICQYCKRLLKGLFRQGMQCKDCKFNCHKRCASKVPRDCLGEVTFNGEPCSVGT---DADMPMDIDSSDVNSDGSRGLDDSEEPS--------PPEDKMFFLDPTDLDVE------------------------RDEETVKTISPSTSNNIPLMRVVQSIKHTKRRSSTVVKEGWMVHYTSRDNLRKRHYWRLDSKCLTLFQNESGSKYYKEIPLSEILRVSSPQDFTSISQGSNPHCFEIITDTVVYFVGEN--NGS---SSHNPVLAATGVGLDVAQSWEKAIRQALMPV--TPQASVCTSPGQGKDHN-LATSISVSNCQVQENVDISSVYQIFADEVLGSGQFGIVYGGKHRKTGRDVAIKVIDKMRFPTKQESQLRNEVAILQNLHHPGIVNLECMFETPERVFVVMEKLHGDMLEMILSSEKSRLPERITKFMVTQILVALRNLHFKNIVHCDLKPENVLLASAEPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRSKGYNRSLDMWSVGVIVYVSLSGTFPFNEDEDINDQIQNAAFMYPPNPWREISSEAIDLINNLLQVKMRKRYSVDKSLSHPWLQDYQTWLDLREFETRIGE-RYITHESDDARWEIHAYTHN-------LEYPKHFIMAPN-------------------PDDMEEDP----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94806-1", "uniprot_id": "KPCD3_HUMAN", "id": "O94806-1", "name": "Serine/threonine-protein kinase D3", "aln": "MSAN-NSPPSAQKSVLPTAIPAVLPAASPCSSPKTGLSARLSNGSFSAPSLTNSRGSVHTVSFLLQIGLTRESVTIEAQELSLSAVKDLVCSIVYQKFPECGFFGMYDKILLFRHDMNSENILQLITSADEIHEGDLVEVVLSA----LATVEDFQIRPHTLYVHSYKAPTFCDYCGEMLWGLVRQGLKCEGCGLNYHKRCAFKIPNNCSGVRKRR-LSNVSLPGPGLSVPRPLQPEYVALPSEESHVHQEPSKRIPSWSGRP-IWMEKMVMCRVKVPHTFAVHSYTRPTICQYCKRLLKGLFRQGMQCKDCKFNCHKRCASKVPRDCLGEVTFNGEPSSLGT---DTDIPMDIDNNDINSDSSRGLDDTEEPS--------PPEDKMFFLDPSDLDVE------------------------RDEEAVKTISPSTSNNIPLMRVVQSIKHTKRKSSTMVKEGWMVHYTSRDNLRKRHYWRLDSKCLTLFQNESGSKYYKEIPLSEILRISSPRDFTNISQGSNPHCFEIITDTMVYFVGEN--NGD---SSHNPVLAATGVGLDVAQSWEKAIRQALMPV--TPQASVCTSPGQGKDHKDLSTSISVSNCQIQENVDISTVYQIFADEVLGSGQFGIVYGGKHRKTGRDVAIKVIDKMRFPTKQESQLRNEVAILQNLHHPGIVNLECMFETPERVFVVMEKLHGDMLEMILSSEKSRLPERITKFMVTQILVALRNLHFKNIVHCDLKPENVLLASAEPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRSKGYNRSLDMWSVGVIIYVSLSGTFPFNEDEDINDQIQNAAFMYPPNPWREISGEAIDLINNLLQVKMRKRYSVDKSLSHPWLQDYQTWLDLREFETRIGE-RYITHESDDARWEIHAYTHN-------LVYPKHFIMAPN-------------------PDDMEEDP----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9Z2-1", "uniprot_id": "E7F9Z2_DANRE", "id": "E7F9Z2-1", "name": "Serine/threonine-protein kinase", "aln": "MSASSTSPLTLPNPFVHSQHQTAPPTPSPSPSPPVPLCVRLSNGNHSVPSPTS---SIHGVSFLLQIGLTREMVTLDPHDLSLSSVKDLVCSIVDQKFPECGFFGLYDKILLFRHDLNSDNILQRLTSAEEIHEGDLIEVVLSA----QATVEDFQIRPHALYVHSYKAPTFCDYCGEMLWGLVRQGLKCEGCGLNYHKRCAFKIPNNCSGVRKRR-LSNVSLPGPSLSVPRPAPAEHATSSLEEQRPHQEPGKRIPSWSGRP-IWMEKMVLGRVKVPHTFVIHTYTRPTICQYCKRLLKGLFRQGMQCKDCKFNCHKRCASKVPKDCLG--VFNGEPASPGP---DSDSTMEVDSSDVNSDSGRGLDDSEEPT--------TPEDKIFFMDSPFMDRE------------------------KDEEPVKTISPSTSTNIPLMRVVQSVKHTKRRSSTVVKEGWMVHYTSKDNLRKRHYWRLDSKCLTLFQNDSGAKYYKEIPLSEILQVEVARDFGSLALGGNPHCFEIITATMVYYVGEN--TGGPHLHIHSPALATGGVGLEVAQSWERAIRQALMPVPVTPQPSVGTAAGQSKDHKELSISISVSNSQIQENVDISSIYQIFADEVLGSGQFGIVYGGKHRKTGRDVAIKVIDKMRFPTKQESQLRNEVAILQNLHHPGIVNLECMFETPERVFVVMEKLHGDMLEMILSSEKSKLPERITKFLVTQILVALRHLHFKNIVHCDLKPENVLLASAEPFPQVKLCDFGFARIIGEKSFRRSVVGTPAYLAPEVLRSKGYNRSLDMWSVGVIIYVSLSGTFPFNEDEDINDQIQNAAFMYPPTPWKDISAEATDLINNLLQVKMRKRYSVDKTLSHPWLQDYQTWLDLREFETRRGE-RYITHESDDARWEKYAYEHS-------LMYPKHFIMAPN-------------------LDDMDEDP----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHC3-1", "uniprot_id": "A0A0B4KHC3_DROME", "id": "A0A0B4KHC3-1", "name": "Serine/threonine-protein kinase", "aln": "---------------------------------------------MEGP----------EVTFLFQFGSVRDAVCVPANSLTLKTLKDLACDFINTKIPDSGLTYLSERILLFVHDYSTPNVLHIINSAAEVVDETLVEIVLTASPILYPTSEMPTLKPHSLNVHSYKGPTFCDFCGEMLFGLVRQGLKCDGCGQNYHKRCVVKIPNNCNRSNDATSRRSFTLQAP-RSPSGSSQQSLVSTEDSTGRNDSSSSLNIPGRHQRTHSSGSRNGLMVLRIPHTFMVHTYGIPTVCQLCKKLLKGLFKQGLQCRDCQYNTHKKCMDKVPHDCTGEAQLSQLQIQAGAKERDNFFREEFDDSDGDDGSEYGKYKSAMSSGVNLVAGRPREAPKALTNAHNSPPELVNGGLVDDSSVSGGETSKSSSDGQSEQSQSSTSSSPSANIPLMRIVQSVKHTKKRGGQALKEGWLVHYTSLDKAVKRYYWRLDSKTITLFVSEQGSKYHKELPLAELLSIES--HLGDPRPECN-YCFELRLPNLSYFVGQDPQVGAKEEQAVRLPPPDSGIGSDIAKSWETSIRQAFMHVT--------------------NTQCCESEEQVQD---MGQLYQIFPDEVLGSGQFGVVYGGVHKKTQREVAIKVIDKLRFPTKQEAQLKNEVAILQNISHCGVVNLERMFETPERIFVVMEKLKGDMLEMILSHARGRLSERVTKFLITQILIALKYLHSQNIVHCDLKPENVLLSSDAEFPQVKLCDFGYARIIGEKSFRRSVVGTPAYLAPEVLRNKGYNRSLDMWSVGVIIYVSLSGTFPFNEEEDINDQIQNAAFMYPPNPWKEISSNAIDLINNLLQVKQRKRYTVDKSLLHYWLQDKQTYRDLRNLEAQVGAGRYLTHEADDLRWDCAGDMXPGCEPEAILESTTELISCSANTTTESYRRSPADCAGCHRLSDCGNSPKSEAMSDRALKWMRFHLCRHIK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . *:**:*:* .*: * : .:.*:*.::***.*.:: *:*:.*: : ::**** *: .: *:*: :.** *: : *:*:**:* .* * ::**:* *****.*****:*****:*********:*** ******..******. .. ..:* .* * . . . .. . : ..... .**. *. .: : :::**** :*:* **:** **:******:**:**:**::* **:* .***:** * :. . *. * :.*..* :... * .: .: . * : :. * :.*:. .: *.*.* ******:***:****::.. :****:***** *: **:******* :*** .:.*:**:**:**:*:* :. .: . * :***: .: *:**:: * . *:* ::*:*** :****:* * . . *: *:*: :. :****.**********:**** *:** *:********:*******:**:********: * *:**** *******:*******:********* :.:*.**:***::****:**: ** :**************:* **********:**************************.***************:************:****************.**::**.:* ********** ****:***:* * **** **: ***::*:: * **:***:** **: . * ...:* .. .* :.* ", "identical_positions": 425, "similar_positions": 213, "identity": "43.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-881", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HA38-1", "uniprot_id": "ZMAT3_HUMAN", "id": "Q9HA38-1", "name": "Zinc finger matrin-type protein 3", "aln": "--------------------------------------------------------------MILLQHAVLPPPKQPSPS--PPMSVATRSTGTLQLPPQKPFGQEASLP--LAGEEELSKGGEQDCALEELCKPLYCKLCNVTLNSAQQAQAHYQGKNHGKKLRNYYAANSCPPPARMSNVV-EPAATPVVPVPPQMGSFKP-------GGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQSNSFSESSELGQRRARKEGNEFKMMPNRRNMYTVQNNSAGPYFNPRSRQRIPRDLAMCVTPSGQFYCSMCNVGAGEEMEFRQHLESKQHKSKVSEQRYRNEMENLGYV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O54836-1", "uniprot_id": "ZMAT3_MOUSE", "id": "O54836-1", "name": "Zinc finger matrin-type protein 3", "aln": "--------------------------------------------------------------MILLQQVWLPLPNRPSTS--PPMSVAARSTRTLQLPPQKAFGQEASLP--LAGEEDLAKRGEPDSALEELCKPLFCKLCNVTLNSAQQAQAHYQGKNHGKKLRNYYAANSCPPPARVSSVVAEPVATPLVPVPPQVGSCKP-------GGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQSHSFSDSAEAGQRRTRKEGSEFKMVATRRNMNPVQSN-SGPYFNARSRQRIPRDLAMCVTPSGQFYCSMCNVGAGEEVEFRQHLESKQHKSKVSEQRYRSEMENLGYVQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7EZ09-1", "uniprot_id": "E7EZ09_DANRE", "id": "E7EZ09-1", "name": "Zinc finger matrin-type protein 3", "aln": "MAMNVKNRDAFYSGADYCNIYSSQPVNYGDCSHYFPRITGPDPILKPPISLMCQQPPQPFQAMTPTQNLRPPPVMMPDPLPFPHCTPPIKPPPHLQLPPNPPLPPPPVISPKPPEEDAQAVAADQEATLEELCKPLYCKLCNVTLNSAQQAQAHYQGKNHSKKLRNFYAGSQQPPPITIPEVVEPVSQQPSATTPTDSANATANQPLTKGASRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQQNATSSDLSDTQRRPRKEGYEYRLMKNRRAQFNTAMP--GPYYNPRPRQRIPRDLAMCVTPSGQFYCSMCNSGASEEAEFRLHLESKQHKSRVSEQRYRSEMENLGYT-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *: * *.. * : . :.. *****: .: . :. . *: : .: :.:********:***********************.*****:**... *** :..** * ...*.: .. .. ..*******************************************.:: *.. . ***.**** *:::: .** . ***:*.*.************************ **.** *** *********:*******.*******. ", "identical_positions": 169, "similar_positions": 62, "identity": "46.43%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-883", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P86091-1", "uniprot_id": "TMPS7_RAT", "id": "P86091-1", "name": "Transmembrane protease serine 7", "aln": "--MDKEKSDPSCKSSDLKISNISIQVVS-----------VPGK---LPGRRLPRKPIGKARPRKQPKKRAPFWNVQNKIILFTVFLFILAVTAWTLLWLYISKTDSKDAFYFVGMFRITNIEFLPEYRQKESREFLSMAKTVQQVVNLVYTTSAFSKFYKQSVVADVSSNNKGGLLVHFWIVFVMPHAKGHIFCEECVAAILKDSIQTSITNRTSVGTLQGLAVDMDSVVLNAGLRSDYSSAVGSDNGCSQYFYADHLTLRYPLEISATSGQLMCHFKLVAIVGYLIRLSIESIQLEADNCITDSLTVYDSLLPIRITCVLLSGYRICEPTRTLMSFVSTNNLMLVTLKSPYVRRLAGIRAYFEVIPEQKCENTILVKEINSFEGKISSPYYPSYYPPKCKCNWTFQTSLSTLGIALKFHNYSITKKSMKGCEHGWWEINEHMYCGSYMDHETIFRVPSPLVHIQLQCSSRLSDKPLLVEYGSYNISQPCPAGSFRCSSGLCVPQAQRCDGVNDCFDESDELFCVTAKPACNTSIFRQHGPLVCDGFQDCEDGQDEQNCTRSIPCTNRTFKCGNDICFRKQNAQCDGIVDCPDRSDEEGCGCSR---------SSPFLHRVVGGSDSQEGTWPWQVSLHFVGSAHCGASVISREWLLSAAHCFHGNRLSDPTPWTAHLGMYVQGNAKFVSPVRRIVVHEYYNSQTFDYDIALLQLSIAWPETLRQLIQPICIPPVGQRVRSGEKCWVTGWGRRHEADSKGSPILQQAEVELIDQTVCVSTYGIITSRMLCAGVMSGKSDACKGDSGGPLSCRRKSDGKWILTGIVSWGYGCGRPNFPGVYTRVSNFVPWIHKYVPSLL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BIK6-1", "uniprot_id": "TMPS7_MOUSE", "id": "Q8BIK6-1", "name": "Transmembrane protease serine 7", "aln": "--MDKEKSDPSCKSSDLKISNISIQVVS-----------VPGK---LPGRRPPRKPIGKPRPRKQPKKRAPFWNVQNKIILFTVFLFILAVTAWTLLWLYISKTESKDAFYFVGMFRITNIEFLPEYRQKESREFLSMAKTVQQVVNLVYTTSAFSKFYKQSVVADVSSNNKGGLLVHFWIVFVMPHAKGHIFCEECVAAILKDSIQTSIINRTSVGSLQGLAVDMDSVVLNAGLRSDYSSAVGSDNGCSRYLYADHLTLRYPLEISATSGQLMCHFKLVAIVGYLIRLSIESIQLEADNCITDSLTVYDSLLPIRSAIL----YRICEPTRTLMSFVSTNNLMLVILKSPYVRRLAGIRAYFEVIPEQKCESTILVKEINSFEGKISSPYYPSYYPPKCKCTWTFQTSLSTLGIALKFYNYSITKKSAKGCEHGWWEINEHMYCGSYMDHETIFRVPSPLVHIQLQCSSRLSDKPLLVEYGGYNISQPCPAGSFRCSSGLCVPQAQRCDGVNDCFDESDELFCVTVKPACNSSSFRQHGPLVCDGFRDCEDGQDEQNCTRSIPCTSRTFKCGNDICFRKQNAQCDGIVDCPDGSDEEGCGCSR---------SSSFLHRIVGGSDSQEGTWPWQVSLHFVGSAYCGASVISREWLLSAAHCFHGNRLSDPTPWTAHLGMYVQGNAKFISPVRRIVVHEYYNSQTFDYDIALLQLSIAWPETLKQLIQPICIPPAGQKVRSGEKCWVTGWGRRHEADSKGSPVLQQAEVELIDQTVCVSTYGIITSRMLCAGVMSGKSDACKGDSGGPLSCRRKSDGKWILTGIVSWGHGCGRPNFPGVYTRVSSFVPWIHKYVPSLL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7RTY8-1", "uniprot_id": "TMPS7_HUMAN", "id": "Q7RTY8-1", "name": "Transmembrane protease serine 7", "aln": "--MDKENSDVSAAPADLKISNISVQVVSAQKKLPVRRPPLPGRRLPLPGRRPPQRPIGKAKPKKQSKKKVPFWNVQNKIILFTVFLFILAVIAWTLLWLYISKTESKDAFYFAGMFRITNIEFLPEYRQKESREFLSVSRTVQQVINLVYTTSAFSKFYEQSVVADVSSNNKGGLLVHFWIVFVMPRAKGHIFCEDCVAAILKDSIQTSIINRTSVGSLQGLAVDMDSVVLNAGLRSDYSSTIGSDKGCSQYFYAEHLSLHYPLEISAASGRLMCHFKLVAIVGYLIRLSIKSIQIEADNCVTDSLTIYDSLLPIRSSIL----YRICEPTRTLMSFVSTNNLMLVTFKSPHIRRLSGIRAYFEVIPEQKCENTVLVKDITGFEGKISSPYYPSYYPPKCKCTWKFQTSLSTLGIALKFYNYSITKKSMKGCEHGWWEINEHMYCGSYMDHQTIFRVPSPLVHIQLQCSSRLSDKPLLAEYGSYNISQPCPVGSFRCSSGLCVPQAQRCDGVNDCFDESDELFCVSPQPACNTSSFRQHGPLICDGFRDCENGRDEQNCTQSIPCNNRTFKCGNDICFRKQNAKCDGTVDCPDGSDEEGCTCSR---------SSSALHRIIGGTDTLEGGWPWQVSLHFVGSAYCGASVISREWLLSAAHCFHGNRLSDPTPWTAHLGMYVQGNAKFVSPVRRIVVHEYYNSQTFDYDIALLQLSIAWPETLKQLIQPICIPPTGQRVRSGEKCWVTGWGRRHEADNKGSLVLQQAEVELIDQTLCVSTYGIITSRMLCAGIMSGKRDACKGDSGGPLSCRRKSDGKWILTGIVSWGHGSGRPNFPGVYTRVSNFVPWIHKYVPSLL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q422-1", "uniprot_id": "A0A8M9Q422_DANRE", "id": "A0A8M9Q422-1", "name": "", "aln": "METAREEGGQGGEEEEAKEDARSVTDVS-----------VEVATVDATLHKLCRRYNRRRRRPKKKKKRNPLFELQNLAILITVVVFVVVVIMWSLLWVFIFRRESNSGVYFAGMFRVANVEFIPEYRHADSSEFMSMANRVQHVITSVYRTSSVGRLYKQTVISDLSNNNQGGVLVHFWMVFLVPQLKTPVVCEECVSAILRDSVLMSMKNRSTVGFLQGLPVDIDSILVNVALRSDYTSTAVG-SQCVDKLYAGVPGVNVPLNVFSSWGGLSCYIKLTSVPGSVIQLTVKSLRLDPSDCIYDALIVYDALLPMRGMIL----YRFCESVSAPISLVSTSNVMLLSFR--LTQGSKVFRGFFQALMEEQCINMIALPDGLGDAGTITSPFYPSLLPRLCSCTWMFQAVSGSLGVALRFQNYMLKLKDSQNCEHGWWKVNEIIYCGNYVDHSTVFRIPAQNPEVVFRCSSRNADQPFSATYSSYNTSQPCPDTHFLCSTGLCVEKSKRCDGLDDCQDESDEIFCSKPPKFCGGTSP-LHPLYICNGEMDCSSGKDETNCTQETSCSGVSYQCDNGACILKKNAKCDGFPDCFDQSDEKNCACGKPTHVKRVLDGTSPQQRIVGGVNAVEGEWPWQVSMHFSGQLYCGASVLSDVWLISAAHCYSKERLADPRMWMAHLGMLNQGSAKHVAEIRRIVVHEYYNARNFDYDIALLQLKKVWPSGLEQYIQPVCLPAPSQTFTEGHRCWVTGWGYRSEQDKVLPTVLQKAEVNVLSQSECKRSYGPVSPRMLCAGVPSGEQDACRGDSGGPLSCQAQTGSRWFLTGIVSWGSGCGRPYLPGVYTRVAKFIDWIQRHIHDENS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:.. . : * . *: ** : . :: :: : : *: **: *::::** **:**.:*::.* *:***::* : :*:...**.****::*:**:****: :* **:*::. **:*:. ** **:..::*:*:*::*:*.**:**:*****:**::*: * :.**:**:***:**: *: **::** ****.**:**:::*..*****:*: . . * :** :. **:: :: * * *::**.:: * :*:*:::*::::..:*: *:* :**:***:* : **:**.. : :*:***.*:**: :: : :*.:*:.: *::* . : : : . *.*:**:*** * *.*.* **: .:**:**:* ** :. *. :.******::** :***.*:**.*:**:*: .: ::**** :*:*: . *..** ***** * **:**** :::****::** *****:** . *. : * :*:* **..*:** ***:. .*.. :::*.*. *: *:**:*** ** * ***:.* *.: .:. :*::** :: ** ******:** *. :*****:* **:*****: :**:** * ***** **.**.:: :**********::.**********. .**. *.* ***:*:*. .* . .*.:******* * * *. . :**:***:::.*: * :** ::.******: **: ***:*********: ::..:*:******** *.*** :*******:.*: **:::: . ", "identical_positions": 369, "similar_positions": 278, "identity": "42.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-907", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6V0K7-1", "uniprot_id": "OIT3_RAT", "id": "Q6V0K7-1", "name": "Oncoprotein-induced transcript 3 protein", "aln": "-------------MPLSLLLACLFTTVTLQSPVVLDPCSAYISLNEPWRNTDHQFDESQSQPLCDNHMDGEWYRFTGMAGDAMPTFCIPENHCGTHAPVWLNGSHPLEGDGIVQRQACASFKGNCCLWNTTVEVKACPGGYYVYRLAKPSVCFHIYCGHFYDICDE-DCHGS-CLDTTECACSPGTSLGPDGQTCFDENECEHNNGGCSEICVNLKNSHRCACGVGRVLRSDGKTCEDIEGCHSNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSSAIEVSVPRELVGGLELFLTNTSCRGVSNGTHVNIIFSLKTCGTVVDVVNDKIVASNLVTGLPKQTPGSSGDIIIRTSKLLIPVTCEFPRLYTISEGYVPNLRNAPLEIRSRNHGIFPFTLEIFKDHEFEEPYRETLPTLKLRDSLYFGIEPLVHVSGLESLVESCFATPTAKVDEILKYYLIRDGCVSDDSVKQYSSRDHLAKHFQVPVFKFVGKDHKEVFLHCRVLVCGVLDERSRCAQGCHRRVRREAGEDEDSAGLQSQTLTGGPISIDWEE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R4V5-1", "uniprot_id": "OIT3_MOUSE", "id": "Q8R4V5-1", "name": "Oncoprotein-induced transcript 3 protein", "aln": "-------------MPLSLLLTCLSTTVTLVSPAVLDPCSAYISLNEPWRNTDHQFDESQNQPLCDNHMNGEWYRFTGMAGDAMPTFCIPENHCGTHAPVWLNGSHPLEEDGIVQRQACASFKGNCCLWNATVEVKACPRGYYVYRLARPSVCFHVYCGHFYDICDE-DCHGN-CLDTTECACSPGTSLGPDGQTCFDENECEHNNGGCSEICVNLKNSHRCACGVGRVLRSDGKTCEDIEGCHNNNGGCSHSCLGSEEGYQCECPRGLVLSEDNHTCQVPVLCKSSAIEVSVPRELVGGLELFLTNTSCRGVSNGTHVNIVFSLKTCGTVVDVVNDKIVASNIVTGLPKETPGSSGDIIIRTSKLLIPVTCEFPRLYTISEGYVPNLRNAPLEIRSRNHGIFPFTLEIFKDHEFEEPYRETLPTLKLRDSLYFGIEPLVHVNGLESLVESCFATPTAKMDEILKYYLIQDGCVSDDSVKQYSSRDHLAKHFQAPVFKFVGKDHKEVFLHCRVLVCGVLDERSRCAQGCHRRVRREVGEDEDSAGLQSQTLTGGPIAIDWED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWZ8-1", "uniprot_id": "OIT3_HUMAN", "id": "Q8WWZ8-1", "name": "Oncoprotein-induced transcript 3 protein", "aln": "-------------MPPFLLLTCLFITGTSVSPVALDPCSAYISLNEPWRNTDHQLDESQGPPLCDNHVNGEWYHFTGMAGDAMPTFCIPENHCGTHAPVWLNGSHPLEGDGIVQRQACASFNGNCCLWNTTVEVKACPGGYYVYRLTKPSVCFHVYCGHFYDICDE-DCHGS-CSDTSECTCAPGTVLGPDRQTCFDENECEQNNGGCSEICVNLKNSYRCECGVGRVLRSDGKTCEDVEGCHNNNGGCSHSCLGSEKGYQCECPRGLVLSEDNHTCQVPVLCKSNAIEVNIPRELVGGLELFLTNTSCRGVSNGTHVNILFSLKTCGTVVDVVNDKIVASNLVTGLPKQTPGSSGDFIIRTSKLLIPVTCEFPRLYTISEGYVPNLRNSPLEIMSRNHGIFPFTLEIFKDNEFEEPYREALPTLKLRDSLYFGIEPVVHVSGLESLVESCFATPTSKIDEVLKYYLIRDGCVSDDSVKQYTSRDHLAKHFQVPVFKFVGKDHKEVFLHCRVLVCGVLDERSRCAQGCHRRMRRGAG-GEDSAGLQGQTLTGGPIRIDWED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RNR8-1", "uniprot_id": "A0A8M1RNR8_DANRE", "id": "A0A8M1RNR8-1", "name": "", "aln": "MYICDFRVLLYLQLDMLFTLFVVLQAVSDTQAIALDPCSAYISLNEPWRNTDYHVNNSAGVPLCDRHVSGEWYRFTGMAGDAMPTFCIQENHCGTHAPIWLNGSHPGPSDGVVTLSACASFNNNCCHWTASVEIKACPRGYYVYRLPRPSVCFHVYCGHFYDICDEIECTGSDCPVEPECRCSEGTILGPDAQTCLDVNECEKGNGGCAELCINTKGSRRCECGPGKVLDVDGKSCKETAGCDNVNGGCSHGCSSDEDSYYCHCPWGLMLGDDKRTCQVPVQCDPSSIEVSVPKDLVGGLELFLSNTSCRGISNGTHINIHFSLKTCGTVIQVSDDKIIGTNLVTGLPRSSPSSNGDLIVRTSKLLLPITCEFPRQYEVSDGYLPSLRNTALELAGHSEGIFPFSLELFKSAEFSEPYNQ-PPQLKLRDVLYFGVEPRERVDGLTAFVENCFATPGPKADQALKYYLIKDGCISDETVRQLSAKDELSKHYQVPVFKFIGKDNREVFLHCRVLVCGQTQGESRCTQGCRKRLRRDVWTDQHQE---QNILSSGPIHILPDP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * : : : .. .******************::.::* . ****.*:.****:************** *********:******* **:* .*****:.*** *.::**:**** *******.:******:*********** :* *. * .** *: ** **** ***:* ****:.****:*:*:* *.* ** ** *:** ***:*:: **.. ******.* ..*..* *.** **:*.:*::****** *...:***.:*::*********:******:*****:** *********::* :***:.:*:*****:.:*.*.**:*:******:*:****** * :*:**:*.***:.**: .:..*****:**:**. **.***.: * ***** ****:** :*.** ::**.***** .* *: ******:***:**::*:* :::*.*:**:*.*****:***::************ : .***:***::*:** . .:.. : *:.*** * : ", "identical_positions": 329, "similar_positions": 140, "identity": "58.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-910", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9P225-1", "uniprot_id": "DYH2_HUMAN", "id": "Q9P225-1", "name": "Dynein axonemal heavy chain 2", "aln": "MSSKAEKKQRLSGRGSSQASWSGRATRAAVATQEQGNAPAVSEPELQAELPKEEPEPRLEG-------PQAQSEESVEP----------------------------EADVKPLFLSRAALTGLADAVWTQEHDAILEHFAQDPTESILTIFIDPCFGLKLELGMPVQTQNQLVYFIRQAPVPITWENFEATVQFGTVRGPYIPALLRLLGGVFAPQIFANTGWPESIRNHFASHLHKFLACLTDTRYKLEGHTVLYIPAEAMNMKPEMVIKDKELVQRLETSMIHWTRQIKEMLSAQETVETGENLGPLEEIEFWRNRCMDLSGISKQLVKKGVKHVESILHLAKSSYLAPFMKLAQQIQDGSRQAQSNLTFLSILKEPYQELAFMKPKDISSKLPKLISLIRIIWVNSPHYNTRERLTSLFRKV----------------------------------------------------------------------------------CDCQYHFARWEDGKQGPLPCFFGAQGPQITRNLLEIEDIFHKNLHTLRAVRGGILDVKNTCWHEDYNKFRAGIKDLEVMTQNLITSAFELVRDVPHGVLLLDTFHRLASREAIKRTYDKKAVDLYMLFNSELALVNRERNKKWPDLEPYVAQYSGKARWVHILRRRIDRVMTCLAGAHFLPRIGTGKESVHTYQQMVQAIDELVRKTFQEWTSSLDKDCIRRLDTPLLRISQEKAGMLDVNFDKSLLILFAEIDYWERLLFETPHYVVNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRLLDKKIHPGLKKLHWALKGASAFFITECRIHASKVQMIVNEFKASTLTIGWRAQEMSEKLLVRISGKRVYRDLEFEEDQREHRAAVQQKLMNLHQDVVTIMTNSYEVFKNDGPEIQQQWMLYMIRLDRMMEDALRLNVKWSLLELSKAINGDGKTSPNPLFQVLVILKNDLQGSVAQVEFSPTLQTLAGVVNDIGNHLFSTISVFCHLPDILTKRKLHREPIQTVVEQDEDIKKIQTQISSGMTNNASLLQNYLKTWDMYREIWEINKDSFIHRYQRLNPPVSSFVADIARYTEVANNVQKEETVTNIQFVLLDCSHLKFSLVQHCNEWQNKFATLLREMAAGRLLELHTYLKENAEKISRPPQTLEELGVSLQLVDALKHDLANVETQIPPIHEQFAILEKYEVPVEDSVLEMLDSLNGEWVVFQQTLLDSKQMLKKHKEKFKTGLIHSADDFKKKAHTLLEDFEFKGHFTSNVGYMSALDQITQVRAMLMAMREEENSLRANLGIFKIEQPPSKDLQNLEKELDALQQIWEIARDWEENWNEWKTGRFLILQTETMETTAHGLFRRLTKLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVRDEIQREFDQESESFTLEQIVELGMDQHVEKIGEISASATKELAIEVALQNIAKTWDVTQLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMILTVQRQWMYLENIFLGEDIRKQLPNESTLFDQVNSNWKAIMDRMNKDNNALRSTHHPGLLDTLIEMNTILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLRIQKVGGPSSKWEAVGMFSGDGEYIDFLHSVFLEGPVESWLGDVEQTMRVTLRDLLRNCHLALRKFLNKRDKWVKEWAGQVVITASQIQWTADVTKCLLTAKERADKKILKVMKKNQVSILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVNSFDWLSQLRFYWEKDLDDCVIRQTNTQFQYNYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAHQILCILSALAAGLTHFHFDGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPDLTDEEVLLLSMRDMNIAKLTSVDAPLFNAIVQDLFPNIELPVIDYGKLRETVEQEIRDMGLQSTPFTLTKVFQLYETKNSRHSTMIVGCTGSGKTASWRILQASLSSLCRAGDPNFNIVREFPLNPKALSLGELYGEYDLSTNEWTDGILSSVMRTACADEKPDEKWILFDGPVDTLWIENMNSVMDDNKVLTLINGERIAMPEQVSLLFEVEDLAMASPATVSRCGMVYTDYADLGWKPYVQSWLEKRPKAEVEPLQRMFEKLINKMLAFKKDNCKELVPLPEYSGITSLCKLYSALATPENGVNPADGENYVTMVEMTFVFSMIWSVCASVDEEGRKRIDSYLREIEGSFPNKDTVYEYFVDPKIRSWTSFEDKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSSLVANQNPILLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRTKQTIKYIREMFLMAAMGPPGGGRTVISPRLRSRFNIINMTFPTKSQIIRIFGTMINQKLQDFEEEVKPIGNVVTEATLDMYNTVVQRFLPTPTKMHYLFNLRDISKVFQGMLRANKDFHDTKSSITRLWIHECFRVFSDRLVDAADTEAFMGIISDKLGSFFDLTFHHLCPSKRPPIFGDFLKEPKVYEDLTDLTVLKTVMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLASSICDYTTFQIEVTKHYRKQEFRDDIKRLYRQAGVELKTTSFIFVDTQIADESFLEDINNILSSGEVPNLYKPDEFEEIQSHIIDQARVEQVPESSDSLFAYLIERVQNNLHIVLCLSPMGDPFRNWIRQYPALVNCTTINWFSEWPQEALLEVAEKCLIGVDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRHNYVTPTKYLELLSGYKKLLGEKRQELLAQANKLRTGLFKIDETREKVQVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAVEEIKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAALAQLREKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLLAAAFLSYMGPFLTNYRDEIVNQIWIGKIWELQVPCSPSFAIDNFLCNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQAQALKWIKNMEGGQGLKIIDLQMSDYLRILEHAIHFGYPVLLQNVQEYLDPTLNPMLNKSVARIGGRLLMRIGDKEVEYNTNFRFYITTKLSNPHYSPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLHTSKITATEVTEQLETSETTEINTDLAREAYRPCAQRASILFFVLNDMGCIDPMYQFSLDAYISLFILSIDKSHRSNKLEDRIDYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCSSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNAAPEKAMLPGEWENACNEMQRMLIVRSLRQDRVAFCVTSFIITNLGSRFIEPPVLNMKSVLEDSTPRSPLVFILSPGVDPTSALLQLAEHMGMAQRFHALSLGQGQAPIAARLLREGVTQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSIPHPDFPISILQVSIKMTTEPPKGLKANMTRLYQLMSEPQFSRCSKPAKYKKLLFSLCFFHSVLLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDALKYLIAGINYGGHVTDDWDRRLLTTYINDYFCDQSLSTPFHRLSALETYFIPKDGSLASYKEYISLLPGMDPPEAFGQHPNADVASQITEAQTLFDTLLSLQPQITP--TRAGGQTREEKVLELAADVKQKIPEMIDYEGTQKLLALDPSPLNVVLLQEIQRYNTLMQTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKAYPSQKPLAAWTRDLAMRVEQFELWASRARPPVIFWLSGFTFPTGFLTAVLQSSARQNNVSVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNRAGSSDRASFVIGIDLRSGAMTPDHWIKRGTALLMSLDS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0C6F1-1", "uniprot_id": "DYH2_MOUSE", "id": "P0C6F1-1", "name": "Dynein axonemal heavy chain 2", "aln": "MASKAEKKRKVAGRGGARAGRVVRAPQSTAGPGATEASLLPDGQEPEPESGKEDSVLGLQAFASWRLTPALHGEANTPPTLLHPQPLFHRRLTTLNLILSCSRAGTRDLALKPFFLSRTMLTGLADATWTGEHDMVLEHFVQDPAVPALTIFIDPVFGLKLELGMPVQTQNQIVYFIRQAPVPITPENFEETVQYGTVRGAYIPALLRLLSGVYVPQIFMNKSWPESIRNHFVSHLHRFLASLTDTRYKLEGHTVLYIPAEAVQMDPEVVVKDKELVQRLETSMIHWTRQIKEVLSAQESVETGENLGPLEEIEFWHNRCMDLSSISKQLVKKGVKHIESILFLAKSSYLTPFRKLAQQIQDGSRQAQSNLTFLSILREPYQELAFMKPKDISEKLPKLISLIRIIWVNSPHYNTRERLTALFRKV----------------------------------------------------------------------------------CECQYHFARWEDGKQGPLPCFFGAQGPQITRNLLEIEDIFHKNLQTLRAVRGGILDVKNTSWHEDYNKFRGGIKDLEVMTQNLITSAFELVRDVEHGVLLLDTFHRLATREAIMRTYEKKAVDLYMLFNSELALVNRELNKKWPYLEPYMTQYSGQAHWVRILRRRIDRVMNCLSGAHFLPHIGTGEESIHTYQQMAQAIDEMVRKTFQEWTATLDKDCIRRLDMSLLRISQEKVGMLDVNFDKTLLILFAEIDYWERLLFETPHYVMNVAERAEDLRILRENLLLVARDYNRIIAMLSPDEQALFKERIRFLDKKIHPGLKKLNWALKGASAFFITECRMHASKVQMIVNDFKASTLTIGWKAQEMSELLLVHITGKQVYRDLEFEEAQREHRMAAQQKLVKLHQDVVNIMTNSYEVFKNDGPEIQQQWLLYTIRLDHMMEDALRLNVKWSLLELSKAINGDGKTTPNPLFRVLVILQNDVRGGGSQVEFSPTLQTLASVVNDIGSHLFATISVFRHLPDILTKRKMNREPIYVLVERDEDIRKIQAQISSGMTNNASLLQNYLKTWDMYREIWEINKDSFIRRYQRLNPPVSSFDADIARYTEVANNVQKEETVLNIQFVMLDCSHLKFSLVQHCNEWQNKFTTLLKEMAAGRLADLHSYLKDNAEKISHPPQTLEELGVSLQLMDTLQHDLPNLETQIPPIHEQFTILEKYEVPVPDTVLEMLESLNGEWLTFQQILLDSEQMLKKHKEKFKTGLIHAADDFKKKAHNLLEDFEFKGPFTSTVGHTAALDQIAQMRAMLMAMRDEENNLRSNLGIFKIEQPVSKDLQILEKELDALQQVWEITRDWEESWNQWKMGCFQTLQTEAMESMAHGLFRRLTRLAKEYKDRNWEIIETTRSKIEQFKRTMPLISDLRNPALRERHWDQVKEEVQREFDQESESFTLEQIVKLGMDQHVEKIAEISASATKELAIEVGLQNIAKTWDSTQLDIVPYKDKGHHRLRGTEEVFQALEDNQVALSTMKASRFVKAFEKDVDHWERCLSLILEVIEMVLTVQRQWMYLENIFLGEDIRKQLPNESALFDQVNNNWKAIMDRMNKDNNALRSTHYPGLLETLIEMNAILEDIQKSLDMYLETKRHIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKLLKIQKVGGSSSKWEAVGMFSGDGEYIDFLHPVLLEGPVESWLGDVERAMRMTLRDLLRNCRVALKKFLNKRDKWVKDWAGQVVITASQIQWTADVTKCLMTAKERSDKKILKVS------ILNKYSEAIRGNLTKIMRLKIVALVTIEIHARDVLEKLYKSGLMDVSSFDWLSQLRFYWEKDVDDCIIRQTNTQFQYGYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKALGIYVIVVNCSEGLDYKSMGRMYSGLAQSGAWGCFDEFNRINIEVLSVVAQQILSILSALTANLTRFYFEGFEINLVWSCGIFITMNPGYAGRTELPENLKSMFRPIAMVVPDSTLIAEIILFGEGFGNCKILAKKVYTLYSLAVQQLSRQDHYDFGLRALTSLLRYAGKKRRLQPDLSDEEVLLLSMRDMNIAKLTSVDVPLFNAIVQDLFPNIELPVIDYGKLRDTIEQEIREMGLQITPFTLTKVLQLYETKNSRHSTMIVGGTGSSKTTSWKILQASLTSLCRAGEPNYNIVREFPLNPKALSLGELYGEYDLNTNEWTDGILSSVMRVACADEKPDEKWILFDGPVDTLWIESMNSVMDDNKVLTLINGERIAMPEQVSLLFEVENLAVASPATVSRCGMVYTDYVDLGWKPYVQSWLEKRPKTEVEPLQRMFEKFINKILSFKKDNCNELVPVPEYSGIISLCKLYTVLATPENGVNPADAENYSFMVEMTFVFSMIWSVCASVDEDGRKKIDSYLREIEGSFPNKDTVYEYYVNPKMRTWTSFEEKLPKSWRYPPNAPFYKIMVPTVDTVRYNYLVSTLVANQNPVLLVGPVGTGKTSIAQSVLQSLPSSQWSVLVVNMSAQTTSNNVQSIIESRVEKRTKGVYVPFGGKSMITFMDDLNMPAKDMFGSQPPLELIRLWIDYGFWYDRVKQSIKHIRDMFLMAAMGPPGGGRTVISPRLQSRFNIINMTFPTESQIIRIFGTMINQKLQDFEEEVKPIGNVVTEATLDVYNTVVQRFLPTPAKIHYLFNLRDISKVFQGMLRANKDFHDTKASITRLWIHECFRVFSDRLVDTADMEAFMGILSDKLGTFFDLTFHHLCPNKRPPIFGDFLKEPKVYEDLVDLTVLKTAMETALNEYNLSPSVVPMQLVLFREAIEHITRIVRVIGQPRGNMLLVGIGGSGRQSLARLASSICDYNTFQIEVTKHYRKQEFRDDIKRLYRQAGVELQTTSFLFVDTQIADESFLEDINNILSSGEVPNLYKSDEFEEIQNHIIDQARAEQIPESSDSLFAYLIERVRNNLHIVLCLSPVGDPFRNWIRQYPALVNCTTINWFSEWPREALLEVAEKYIIGVDLGTQENIHRKVAQIFVTMHWSVAQYSQKMLLELRRYNYVTPTNYLELVSGYKKLLGEKRQELLDQANKLRTGLFKIDETREKVEVMSLELEDAKKKVAEFQKQCEEYLVIIVQQKREADEQQKAVTANSEKIAIEEVKCQALADNAQKDLEEALPALEEAMRALESLNKKDIGEIKSYGRPPAQVEIVMQAVMILRGNEPTWAEAKRQLGEQNFIKSLINFDKDNISDKVLKKIGAYCAQPDFQPDIIGRVSLAAKSLCMWVRAMELYGRLYRVVEPKRIRMNAAMAQLQEKQAALAEAQEKLREVAEKLEMLKKQYDEKLAQKEELRKKSEEMELKLERAGMLVSGLAGEKARWEETVQGLEEDLGYLVGDCLIAAAFLSYMGPFLTNYRDEIINQIWIRKIRELQVPCSPRFAIDNFLTNPTKVRDWNIQGLPSDAFSTENGIIVTRGNRWALMIDPQGQALKWIKNMEGNQGLKIIDLQMHDYLRVLEHAIQFGFPVLLQNVQEYLDPTLNPVLNKSVARIGGRMLIRIGDKEVEYNPNFRFYLTTKLSNPHYNPETSAKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIAAGKRKLKELEDEILRLLNEATGSLLDDVQLVNTLQTSKITATEVTEQLETSETTEINIDLAREAYRPCAQRASVLFFVLNDMGRIDPMYQFSLDAYIGLFILSIDKSHRSNKLEDRIEYLNDYHTYAVYRYTCRTLFERHKLLFSFHMCAKILETSGKLNMDEYNFFLRGGVVLDREGQMDNPCTSWLADAYWDNITELDKLTNFHGLMNSFEQYPRDWHLWYTNSSPEKAMLPGEWENACNEMQRMLIVRSLRQDRVAFCVTSFIVSNLGSRFIEPPVLNMKSVMEDSTPRSPLVFILSPGVDPTSALLQLAEHTGMAHRFHALSLGQGQAPIAARLLREGVNQGHWVFLANCHLSLSWMPNLDKLVEQLQVEDPHPSFRLWLSSSPHPDFPISILQASIKMTTEPPKGLKANMTRLYQLMTEAQFTHCSKPAKYKKLLFALCFFHSILLERKKFLQLGWNIIYGFNDSDFEVSENLLSLYLDEYEETPWDALKYLIAGVNYGGHVTDDWDRRLLTTYINDYFCDLSLTTPFYRLSVLDTYYIPKDGSLASYKEYISMLPSMDPPEAFGQHPNADVASQITEARTLFETLLSLQPQITP--TRVGGQSREEKVLELAADVKQKIPEMIDYEGTRKLLALDPSPLNVVLLQEIQRYNKLMKTILFSLTDLEKGIQGLIVMSTSLEEIFNCIFDAHVPPLWGKVYPSQKPLASWTRDLAVRVEQFETWASRARPPVLFWLSGFTFPTGFLTAVLQSAARQNNISVDSLSWEFIVSTVDDSNLVYPPKDGVWVRGLYLEGAGWDRKNSCLVEAEPMQLVCLMPTIHFRPAESRKKSAKGMYSCPCYYYPNRAGSTDRASFVIGIDLRSGSMTSDHWIKRGTALLMSLDS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B7Q1-1", "uniprot_id": "A0ACD6B7Q1_DANRE", "id": "A0ACD6B7Q1-1", "name": "Dynein axonemal heavy chain 2", "aln": "MADPETPQPARSSSSMSKQSDSRKGHSKSKRISSTPAPDDMSPQAPEVAAEREKSVS-----------EVTVAVDEVDS---------------------------YKKRLREAFKQRLALSGISKESWTEENEQALDKFISDSSVRLLVVYHDPFTGLYVDYAMPAQVVEQMSYFIRAPDSMITEESFRSSVQFGSVRGGAIEGLLRMMNGVHTPQVTLSTTWPETSKNNYSAELHRFLTKLTDSRFKLLGSTVLYIPLEALQHRPEEAVKNKNLVQRLEMVVIHWTRQIKAVLSAQSVSDIGDTLGPLEEISFWKSRCADLDSISTQLQKPGVRHIQEILQLYTSTYIPPFCKLAKQIQESSLQAQSNVTFLSLLKEPCEELAQLKPCEIAPKLAHILNLIRVIWVNSSYFNTRDRITALLRKISNEIIRLCCREISLNRIFQGYAVSSKQILNDCIQCCLAWKELYLHTSQLHHKHSSQGWSLDQISIFALVDSFMQRCKDLIEICECQQQFARWEDGERVPLPCFAGRLGSEVTQKLLYIEATFDKSLQVLQSVQD-ILDVRNPSWHEDYSRFRAKLKDLEVMMQNLITSTFEMVNCVEEGVQLLDVFQHLSGREAIKRTIDRKTVDVYNLFHSELVEINLVMCRTSSLIPVQMPRYAGQIHWTKALHSRVERSMEVLRRAHFLPHVRSADEMHVIYVKLCQTLDEKVRRIFTDWSQSLSKECHSSLDQPLMIRCKGKTGLLDINFNKNLLKLFNEIHYWDRLQFEIPHFVTEVYQRREELHNLRENVLLVVRDYNRIIKDLNADELGLFSERIRFLDKKIQPGLSKLHWSTKGTPSAFINDCRVHANKVQLMVDEYKAANLATSKHCEQISELLLVHLDGKTVYRDHEFQEDQQTHQHSQMLRLQNAHQDIIKIMARVYGTFHLDGPEVQQHWTSYMEKIDQMLEEAFRVNIKRSLQELSKAINGDGKISPNPLFRVEVVLTPETARSTAQVDFSPSPQKLAHIVNSISSQLIKTISGFKRLPDLLTRQQSQRKPIHSIIEQDEEICKIQGAIAAGMVTNASYLQTYLKTWDKHREIWEIEKDSFIQRYQRLNPTVTSFDADIARYTEVANNVQKEETLLSVQFVLLDCSPLKFSLLQHCNEWQSKFTQLLSLMASSKLKELHSFLQENAVRLSQPPQTLTDLGESLKLLETLQADLNKIESQIPPIHEQYAILTKYEVAVDPAVLELLEALNAEWVWFQQVVIDSDIMLKKHKDTMKSGLILSSEEFQKKTQTFLQSFSSNGPFGSSVTPHSALQQVSELRAQLEALKEEEQNICSGLNIFTIEQPASKDILALEKDVDYLQQVWEIARQWEDLWAEWKGGHLASLQTEVMDNTAQTMFKTLHKLSRAFKDKHWEIVDSSKSRIEQFKKIIPLITDLRNSALRERHWNQIRQEVQQTFDPSSADFTLEKIVALGLDHHAESISDISGAASKELSIEQTLEGIMKTWKEMSLDITPHKDKGHHKLRGTDEVFQALEDNQVTLSVIKASRFVKAFEKEVDHWERCLSLVLEVIEMILTVQRQWMYLENIFLADDIRKQLVRETAEFDAVTFSWKIIMERLDKDKNALRGTHHPGLLEKLSEMNTKLEEIQKSLDMYLETKRQIFPRFYFLSNDDLLEILGQSRNPEAVQPHLKKCFDNIKSLRINKVG-TGNKSEASGMFSADGEFVDFTHPVLLEGPVEAWLCDVERTMRWTLKDSLRNCSIALKKMPGKRGKWVRDWPGQMLITASQIQWTTDVTRALMTSKERADKSALKSLKKKQVSMLNQYSEAIRGNLTKILRLKIVALVTVEVHARDVISKLAKGGCCDVNAFDWLCQLRLYWEKDVDDCIIRQTNTHFRYGYEYLGNSGRLVITPLTDRCYMTLTTALHLHRGGSPKGPAGTGKTETVKDLGKSLGMYVIVVNCSEGLDFKSMGRMYSGLAQTGAWGCFDEFNRINIEVLSVVAQQILSILSALSAGLNNFSFEGRQINLIWSCGIFITMNPGYAGRTELPDNLKSMFRPISMVVPDSTLIAEITLFAEGFNNCKVLAKKVFTLYSLAVQQLSKQDHYDFGLRALTSLLRFAGKKRRARPDIVDEEILLMSMKDMNIAKLSSIDLPLFNGIIQDLFPAVETPTIDYGKLKEAVEAELRLSGLQVIPFTVTKVIQLYETKNSRHSTMIVGKTGSGKTVTWRTLQNTLSTLHRNGEPGFNLIRECPLNPKAVSLGELYGEYNLSTNEWTDGVLSSLMRMACADEKPDEKWIVFDGPVDTLWIESMNSVMDDNKVLTLINGERISMPEQVSLLFEVEDLSVASPATVSRCGMVYSDYSDLGWKPYVQSWMEKRQKVETDLLWQLFERYIDNTLAFKKTHCKELVAITELNGVASLCRLYHSLATAENGVKPADSENYGRMVELWFIFSLIWSVCASVDEEGRKKIDTFLREIEGSFPNKDTIYEYYVDTKNKTWASFEDKLPKGWRYASNAPFYKIMVPTVDTVRYHYLVKALVSTQHPVLLTGPVGTGKTSVAQSVLQSLDNITWATLTVNMSSQTSSNNVQEIIESRVEKRIKGVYVPVGGKKMVVFLDDLNMPAVDNFGSQPPLELLRLWIDYGFWYDRQKQTLKYIKDLFLLGSMGPPGGGRTHISGRLQSRFNLINMTFPTESQIKRIYGTMISQKLQEFEEEVKPIGGILTQATLELYHAITSRFLPTPAKIHYLFNLRDISKVFQGLLRAHKDFHDTKQSITRLWIHECFRVFSDRLVDHADMETFVGVLSEKLASHFDVPFHTICPNKQPPLFGDFLREPQIYEDLLDFKALKVHMENQLEDYNLTPGVVPMSLVLFRDAIDHVTRLVRVISQLRGNMLLVGIGGSGRQSLTRLAAYICRFTVFQVEVTKQYRKQEFREDIKKLYRLTGVENKPTVFLFNDTQIVDESFLEDINNILSSGEVPNLYKADELDEIQSALSDSARKDNILETPDAMFNYLIERVRNNLHIVLCMSPVGDPFRNRIRQYPALVNCTTIDWFSEWPRDALLEVAERCLDGLSLGSDDGIQTKVASIFVTVHQSVAQFSHRMKVELKRHNYVTPTNYLELVSGYKKLLSEKRDELGEQVSKLRNGLFKIDDTRTKVEAMSVELEEAKKKVAEFQKQCEEYLVVIVQQKREADEQQKAVGAHSEKIEAEEIKCKAMAENAQRDLDEALPALEEAMKALESLNKKDMTEIKSYGRPPALVETVMQAVMILRGCEPTWAEAKRQLGEGNFIKQLVNFDKDNISDRVLKTIGQYCTQPDFQPEIIGRVSLAAKSLCMWVRAMEVYGRIFRVVEPKRARLHGAMTQLAEKQAALAEAQGKLREVGEKLDHLKRQYDEKLAQKEELRRKSEDMELKLDRAGKLVSGLAGERVRWKETVDGLEKNMSCLVGDCLLAAAFLSYMGPFLSNYRDELVTDIWMKQVRELEVPCSPGFSFAVFLSKPTAVREWNIQGLPSDAFSTENGVIVTRGNRWPLMVDPQGQALKWIKNMEFKQGLKVIDLQMPDFLRILENAVQFGSPVLLQNVQEELDPSLAPILNKSLTRVGGRFLLKLGDKEIEYSPEFRFYMTTKLSNPHYTPEISSKTTIVNFAVKEQGLEAQLLGIVVRKERPELEEQKDSLVINIASGKRKLQELEDEILRLLNEATGSLLDDVQLVNTLQTSKVTATEVAEQLEISELTESQIDTAREAYRPCAQRASILFFVLNDLGCIDPMYQFSLDAYINLFILSIESSPRSHKLEERINNLNRHHTYAVYRYTCRGLFECHKLLFSFHMCAKILEASGKLNMDEYNFFLRGGLVLDTKKQMDNPCSHWLSDSNWDNITELDKLTNFHELMASFEQYPRDWHHWYTNPEPEKAPLPGEWENSCNELQKMLIVRSLRQDRVSLCVTAFVINNLGSQFVEPPILDMKAVVADSTTRTPLIFVLSPGVDPTAALLQLAETSGMGQRFFALSLGQGQAPIATRLIKEGVANGHWVFLANCHLSLSWMCELDKLVDELQVQECHPDFRLWLSSSPHPEFPIAILQTGIKITTEPPRGVKWNMKRLYQRVSETQFLRCSRPLLYRKLLFSLCFFHSVILERRKFLQLGWNIIYSFNDSDFEVSENLLSLYLDEYEEIPWDALKFLIAGINYGGHVTDDWDRRLLTTYINQYFCPAVIDTPFFKVSSLVSYYVPRDGPQSSYVDYISQLPALEHPELFGQHPNADIASQITEARTLFHTLLSLQPQVTSTDTTSAGASREDKVLELSADVLQKIPAEIDYEGTRKLLKDDVSPLNVVLLQEIQRYNTLLHTIRLSLLELEKGIKGLVVMSSSLEETFNCIHDARVPPLWEKAYPSLKPLASWTRDLCQRVEQFARWAETARPPVLFWLSGFTFPTGFLTAVLQSSARQNNVSVDTLSWEFSVTTVEDNNLLFPPKDGVLIQGLFLEGAGWDKKASCLVEAEPMQLVCPMPTIHFKPVESRKRLAKNMYSCPCYYYPVRSGSSGRQSFVVAVDLKSGAVPYDHWIKRGTALLMSLDN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:. : :. . :: . :. : . . : :*.. . .. . . :: * .* *:*::. ** *:: *::* .*.: *.:: ** ** :: .**.*. :*: **** . ** *.*. :**:*:*** * .***::.**..**: .. ***: :*:: :.**:**: ***:*:** * ****** **:: ** .:*:*:****** :******** :****. : *:.*******.**:.** **..**.** * **:*::.** * .*:*:.** ***:***:.* *****:****:*:** :*** :** :*: **.:::.***:*****.::***:*:*:*:**: *:** :*******:: ***** * *.::*::** ** *.*.*:.*::*:. ****:*..*****.:**. :****** ******:**:*. * .** ***.*::*: **** ** ::*:**:* **:***. :* :. . : :.:*:*: :*.: *: *::* * * *****:: :..* * :: *::** **: * :*: :*.*:* ** .*: .: *.*:**:**:*.** ** **.**:** ** **:* :* :* *:*: ****:***.******* *..** .**.****:*****:***.**:*: **:.: **.:**:**.***::*:::**:.*: . :.:::** ***:: ** **** **:* *: *: : :* : ***::.**:. * .*: ****:**:* * ::*:*:*:*:*:*:* ** *********** :*****:* *:* : . :**:***: *.** :**.*..:*: *** * :***:**::: :*:** ::*:**:* *** *::**..*** **.****** :******:*****:*******.*:** ******************: .:***:**** *****:*******.**: ** **:.:* :**::*::** ::*:***** :** **:*:::*: ** ::*:********::** ****.* :***:*::**.**: *** ::**. ******:.:*:*** ::::*:**::.:*:.*. :* * *.* :**:*::::** * *:::**:.: :.*.**.**** ***: ***::* ***:***:*:**: * :** * : ****.*:. *: :*: * :*:: :**::***:::::*:*****: :***:****.*******:*:::*:*: ** .* .****:** **:*:*.*.*.:**.:*:***:** *:.* ***. .***.*:******:****:***********:**.:***********:**********:******:***************.:****** .*:: ** *. .** **:*::**:****.**:****:.* ***: **:*************:************************************** *:*:*** ...* ** ****.***::** *.*:******:** ***::** **:* **** :**:*: .**.***::*.**::*********:***:.*:*:***:**. ** :**:************:*********:*:*****:.** *.* **.:****.***:*****:***:******:*:*.****************************************************:**:************:************:*********************:***.*****:*.*..* *:* :***:********************:*********:************ **.***.***:*****:***********:****************:****** :**: ***:**:**:*******:*:* ****.*:***** :* *.******::::* *:* *** ***:***:**************** ***.**.:*: ** :*::* * *:*.:*::** ******:*********:*.*******:***:** ************:***********.*******************:************:*::*************:** ***********:*** *.*.: * ::**: *:: *:*** :*:***.:.* .*: ***:** ***.****:***.*** ***: *:**:**********:***:**::*************:***:*:.* ::*:***:****.***..*****************:***.:**:.*:*:**.*********:******** . *:.*.****:**:*****.********* ******.***.*:.*:******* * *********:************ **::*:*:::**:.:********* ** **:****:*******:*** **:****.****:*********.::*:***::*:::..******:*:***************:***:******* ******************** ** *:*:*::*:**.:.**:.** :**.*:**:*****:**::**** *:..**. **. *::***:*.****.*****:**:*:**:****.* *****************:***: ** :..**:****:*******:***:*** :*** :.* *:* ****.**********************.**::***. : *.** ::: *:.*::* ******:********:**:****** *************:******::*******: : *:.**:::.*: ***.****:* ****:*::* :**:*:******:****:*******.***:** *..***.******:** **:.**:***:*****************:*************** *:**** **:**:*:*:***:**:**********:*********: ********** ** ********** ************* ****.*:*********:***.** **:******:********************:***::******* *::.*::** ********** *****.***: **:*************:***:*****:*** ********:.**:***:***:::. ******:************:*****::.:**: :: **:***** *:: ** :** **:****************:********.**:***.********** ****:***** *:**:**:*::** ********* ***:* *:****::*:***:*:::****:**..:****:*********.** *:******************************************:*****:***************************:***:*****:**** ** ** : * *************:*******:* *************.******:.* **:***:**: ** :*********** *** ***************:****************:*** : ******: **:*: ************** ** ********** ****. **** *******:***:*:************::***:*::.****:*:***:*:**:*: ***.*:**:*:********:******* **.:**.************:**::*** :**************** :*****::***:: **.******* ***:***:***..**:*****:*:* **.**** ::*.** :**:* *:****:******::***:***********.********************** ******:****:********************:*** : ***.::* * :*::*:**. :** :*** **.:: ** ********:*******:***.********:*. * .* :**:*****:*** **** ******:*** * ***************.*::** :** :*****:**:***:**** ****.**:***** *.*** ****:*****. ***** **. *****:*******************:*****:***:***** *:**:*.**::****** ::**:*******:* ************* ******:*.****: **.********** *:**:.* ***:.:**:**::. ***************.", "identical_positions": 2981, "similar_positions": 972, "identity": "65.57%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-923", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6EV76-1", "uniprot_id": "FUT8_RAT", "id": "Q6EV76-1", "name": "Alpha-(1,6)-fucosyltransferase", "aln": "-------MRAWTGSWR-WIMLILFAWGTLLFYIGGHLVRDNDHPDH-----SSRELSKILAKLERLKQQNEDLRRMAESLR------------------------------IPEGPIDQGTATGRVRVLEEQLVKAKEQIENYKKQA-RNGLGKDHELLRRRIENGAKELWFFLQSELKKLKHLEGN-----ELQRHADEILLDLGHHERSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSKARKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETCTDRSGLSTGHWSGEVNDKNIQVVELPIVDSLHPRPPYLPLAVPEDLADRLVRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFKHPVIGVHVRRTDKVGTEAAFHPIEEYMVHVEEHFQLLARRMQVDKKRVYLATDDPALLKEAKTKYSNYEFISDNSISWSAGLHNRYTENSLRGVILDIHFLSQADFLVCTFSSQVCRVAYEIMQTLHPDASANFHSLDDIYYFGGQNAHNQIAVYPHKPRTDEEIPMEPGDIIGVAGNHWDGYSKGVNRKLGKTGLYPSYKVREKIETVKYPTYPEAEK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTS2-1", "uniprot_id": "FUT8_MOUSE", "id": "Q9WTS2-1", "name": "Alpha-(1,6)-fucosyltransferase", "aln": "-------MRAWTGSWR-WIMLILFAWGTLLFYIGGHLVRDNDHPDH-----SSRELSKILAKLERLKQQNEDLRRMAESLR------------------------------IPEGPIDQGTATGRVRVLEEQLVKAKEQIENYKKQA-RNGLGKDHEILRRRIENGAKELWFFLQSELKKLKHLEGN-----ELQRHADEILLDLGHHERSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSKARKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETCTDRSGLSTGHWSGEVNDKNIQVVELPIVDSLHPRPPYLPLAVPEDLADRLLRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFKHPVIGVHVRRTDKVGTEAAFHPIEEYMVHVEEHFQLLARRMQVDKKRVYLATDDPTLLKEAKTKYSNYEFISDNSISWSAGLHNRYTENSLRGVILDIHFLSQADFLVCTFSSQVCRVAYEIMQTLHPDASANFHSLDDIYYFGGQNAHNQIAVYPHKPRTEEEIPMEPGDIIGVAGNHWDGYSKGINRKLGKTGLYPSYKVREKIETVKYPTYPEAEK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYC5-1", "uniprot_id": "FUT8_HUMAN", "id": "Q9BYC5-1", "name": "Alpha-(1,6)-fucosyltransferase", "aln": "-------MRPWTGSWR-WIMLILFAWGTLLFYIGGHLVRDNDHPDH-----SSRELSKILAKLERLKQQNEDLRRMAESLR------------------------------IPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYKKQT-RNGLGKDHEILRRRIENGAKELWFFLQSELKKLKNLEGN-----ELQRHADEFLLDLGHHERSIMTDLYYLSQTDGAGDWREKEAKDLTELVQRRITYLQNPKDCSKAKKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRTLILESQNWRYATGGWETVFRPVSETCTDRSGISTGHWSGEVKDKNVQVVELPIVDSLHPRPPYLPLAVPEDLADRLVRVHGDPAVWWVSQFVKYLIRPQPWLEKEIEEATKKLGFKHPVIGVHVRRTDKVGTEAAFHPIEEYMVHVEEHFQLLARRMQVDKKRVYLATDDPSLLKEAKTKYPNYEFISDNSISWSAGLHNRYTENSLRGVILDIHFLSQADFLVCTFSSQVCRVAYEIMQTLHPDASANFHSLDDIYYFGGQNAHNQIAIYAHQPRTADEIPMEPGDIIGVAGNHWDGYSKGVNRKLGRTGLYPSYKVREKIETVKYPTYPEAEK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BLI2-1", "uniprot_id": "A0A8M2BLI2_DANRE", "id": "A0A8M2BLI2-1", "name": "Alpha-(1,6)-fucosyltransferase", "aln": "-------MRPWTGSWR-WIALVLLAWGTLLFYIGGHLVKDSEHAPR-----SSRELAKILTKLERLKQQNEDLRRMAQSLR------------------------------IPEGQSDGPISSGRLRSLEEQLSRAKQKIQSFQRLSGEAGPGREQEELRRKVENGVRELWYFIHSEIQKLSHVNPT-----DRQKQTDALLQDLGHQQRAIMTDLHELAQADGAGEWRDKEARDLSILVQNRISFLQNPQDCSKARKLVCNINKGCGYGCQLHHVVYCFMIAYGTQRVLILESHNWRYAPKGWETVFKAVSETCTDRSGATTGHWSGEAHDRDVQVVELPIVDSLHPRPPYLPLAVPEDLAPRLQRLHGDPSVWWVSQFVKFLVRPQAWLEKEIQETCLKLGFKHPIIGVHVRRTDKVGTEAAFHPIEEYMVHVEEQFQSMAQRGHVDKKRVYLATDDPALLQEAKTKYTDYEFISDNSISWSASLHNRYTENSLRGVILDIHFLSQTDFLVCTFSSQVCRVAYEMMQTLHPDASSFFRSLDDIYYFGGQNAHNQIAIYPHQPRTAEDIPLDPGDVIGVAGNHWDGNSKGINRKLGRTGLYPSYKVKEKIETVKYPTYPEADKMLSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYV5-1", "uniprot_id": "FUT8_DROME", "id": "Q9VYV5-1", "name": "Alpha-(1,6)-fucosyltransferase", "aln": "MLLVRQLFGASANSWARALIIFVLAWIGLVYVFVVKLTNTQGQQAAGESELNARRISQALQMLEHTRQRNEELKQLIDELMSDQLDKQSAMKLVQRLENDALNPKLAPEVAGPEPESMFESAPADLRGWNNVAEGAPNDLEAGVPDHGEFEPSLEYEFTRRRIQTNIGEIWNFFSSELGKVRKAVAAGHASADLEESINQVLLQGAEHKRSLLSDMERMRQSDGYEAWRHKEARDLSDLVQRRLHHLQNPSDCQNARKLVCKLNKGCGYGCQLHHVVYCFIVAYATERTLILKSRGWRYHKGGWEEVFQPVSNSCHDAGTANTYNWPGKP---NTQVLVLPIIDSLMPRPPYLPLAVPEDLAPRLKRLHGDPIVWWVGQFLKYLLRPQPTTRDFLTSGMRNLGWERPIVGVHVRRTDKVGTEAACHSVEEYMTYVEDYYRTLEVNGSTVARRIFLASDDAQVIEEARRKYPQYQIIGDPEVARMASVSTRYTDTALNGIILDIHLLSMSDHLVCTFSSQVCRVAYEIMQTMYPDAAHRFKSLDDIYYYGGQNAHNRRVVIAHKPRTHEDLQLRVGDLVSVAGNHWDGNSKGKNTRTNQGGLFPSFKVEEKVDTAKLPLYAGI------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :.** : :.::** *:: : :*.. . : .:*.::: * **: :*:**:*::: :.* ** : . :* :: * :.:: . . : * **:::.. *:* *: **: *: : : :. : .* : ..::*::::*: : *:** **.***:**: ***.*: .****.**.:*:****::*****************::**.*:*.***:*:.*** *** **:.**::* * . .* :*.*: : **: ***:*** *************** ** *:**** ****.**:*:*:***. .. : . :**:::*::*************** *.:****.:**: :: : . . :*::**:**. :::**: **.:*::*.* .:: *.: .***:.:*.*:*****:** :*.***************:***::***: *:*******:*******: .: .*:*** ::: : **::.******** *** * : .: **:**:**.**::*.* * *. ", "identical_positions": 254, "similar_positions": 185, "identity": "40.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-929", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W3V7-1", "uniprot_id": "Q9W3V7_DROME", "id": "Q9W3V7-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQMHMELSYGRG----------------------------YDPIGRQPPSLPPP---------------------------------------------------------SQQHWSSNGFSDDSAS------------------------CFRRGSYIELASGAMRRVEDIRTEDFIQSALRSQLFELREATVVRIDWSGCPSLVTLTFSYDTHHAKMDLQVQPGHPMFVYGQGWASCDPQLSLQLYELKCQQLQVGDICLSLVPNEQPAAPCPPQPAPPPPCPPPSLPPSMEMPVPMGSPPTGSYGFLPFKHPYEMYAQMASFVAVYTQHMMGKLNY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8N7UW40-1", "uniprot_id": "A0A8N7UW40_DANRE", "id": "A0A8N7UW40-1", "name": "", "aln": "MNPSPDRSKECLPPKKRESRQGSTDQPAPEDDFKPPAPFRSRRPHQPTEGPREGGDLLPPVPLPLPWPVSYTPSIHPHTYLPLQLGERRGSWREALCGRGVDGGLEQSVPQHSRWLSSDIPHINMQPLLSVPTFKSVYSGDSREMWSCGLSRPDYSSSLFSPHVFPQPAVYPPDSLPDSRLRYQSRRHNGIDGQDCKSGFSRRVPSCNDYGNDSVSRLDAPHANGRRRQENTSRQTPEKRLPPQVSTSAHSSPWDRDPRGTPKASMPPSPDTKAGKAITSQDHFGGSASPAGAQIYYTLGSLCPSAQQNPQVFPQPRSPLSCSARSSQNQHNSHGVETDWSSPAGPCRPPLAVLMGPDPPPSAVLPHFAKGSLIELAGGHLKRVEELKTEDFLRSADTLPEFHLSSCTILLISPGPTYGFNHLQVLLTDRNTQELLTVLSEYPFFVRDRGWSSCSPQRSAQLYGLQCRQLSTGDVCLALTPTPTHKPNLAPSESRGPPGGSREPPSGTELQN-THRPRKRRWSAPELEPGAQTHTHSPLPQHSHTHH-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. : ** ** * .*:**. **:: .*:*.. * :* * :** ****.* ::***:::****::** *.* ..*:: *. . .: * . :::: * * . :*:** .:**:**.** * *** *:*:**..**:**:*.*. . .*. : ** . . *.. *: * . :. :: : ::: . :*:* ", "identical_positions": 69, "similar_positions": 73, "identity": "12.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-930", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VI64-1", "uniprot_id": "HUMMR_MOUSE", "id": "Q8VI64-1", "name": "Protein MGARP", "aln": "-MYLRRAVSKTLALPRRAPPGPAPLGKDASLRRMSSRKFPGTSGSNMIYYLVVGVTVSAGGYYTYKALTSKQVRRTEHVAEPKEQTK---------------------------------AELQPLPGEKEEHVAEAEQVCSEPGD-TAVTEAESVDAEEVPEAAVVLPEESQASAPSEVPAEAAVVEASLSSSEPELKITEASL-----------------------VETTESVPESTQEVESAAPDQDDVCNEGADTSQEGADTSQEGADTSQEGA--DTTKEEADNSKEAEGTTTEDPRSISEESAELEE-SPPLGSEPPAQPESQEEETQVTEETASPQG---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDB4-1", "uniprot_id": "HUMMR_HUMAN", "id": "Q8TDB4-1", "name": "Protein MGARP", "aln": "-MYLRRAVSKTLALPLRAPPNPAPLGKDASLRRMSSNRFPGSSGSNMIYYLVVGVTVSAGGYYAYKTVTSDQAKHTEHKTNLKEKTK---------------------------------AEIHPFQGEKE-NVAETEKASSEAPE-ELIVEAEVVDAEESPSATVVVIKEASA-CPGHVEAAP---ETTAVSAETGPEVTDAAA-----------------------RETTEVNPETTPEVTNAALDE---------------------AVTIDNDK--DTTKNET-----------------SDEYAELEEENSPAESESSAG-DDLQEEASVGSEAASAQG---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RSA4-1", "uniprot_id": "A0A8M1RSA4_DANRE", "id": "A0A8M1RSA4-1", "name": "", "aln": "MMFCRAAWRRLAPLARKTLTPPLSSNAVVPIRQMSFG-LP-VSGTNMAYAVLCGSSLTAAIVYAYKTINSDSARYNERIAQIEARTKRAVAEVSVAAEAAAVVESTASEHVAIAETTAVETVVEVLEAEAEESPAESLEAAVELEAGSAIVQAVVAEAEEPAAPVVEDVAAEAAVAETTVTAMSDLMSAVKILAGSTVEIAAASVGDQHLVTAVRLSEDHNTAEILNGLDTVDVKAEDPEPVGEAAIDPADLNTAEQDQLSSALHPVDKTTVEVADDNNVDSEANDSHVAETDVESLSLSEGIEMENTVELLESTNPVEVMTAEDDTISGAAESMTETVEVVHQIMEEYKALYDDLAGTETEHTDLTEPPDMEMSETVLDEVEETKPAEASEEDDESGNVTMTMPQA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: * * : .*. :: . * . . ..:*:** :* **:** * :: * :::*. *:**::.*...: .*: :: : :** : :. : .* * **: :.. * :.:* .:*** . ..* * . * * . .: : . ::: *: :*.: .* . * .** * : :. *: ::: :: .** * . * .. .: . . : ", "identical_positions": 48, "similar_positions": 86, "identity": "11.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-933", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LAZ2-1", "uniprot_id": "A0ABK0LAZ2_RAT", "id": "A0ABK0LAZ2-1", "name": "Telethonin", "aln": "LGFLYRLGYVILLVKGPHYDKPLSSLNKGEQAEDSAKVARGCPRAWSEVVFAACQTPGGATLRTQAPSRASRRLWKLTSDLRAIRIWVPQPPPWIQSPITTKLSCQVSEENQERREAFWAEWKDLTLSTRPEEGCSLHEEDTQRHETYHRQGQCQAVVQRSPWLVMRLGILGRGLQEYQLPYQRVLPLPIFTPTKVGATKEEREETPIQLRELLALETALGGQCVERQDVAEITKQLPPVVPVSKPGPLRRTLS---RSMSQEAQRG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70548-1", "uniprot_id": "TELT_MOUSE", "id": "O70548-1", "name": "Telethonin", "aln": "-------------------------------------------------------------------------------------------------MATSELSCQVSEENQERREAFWAEWKDLTLSTRPEEGCSLHEEDTQRHETYHRQGQCQAVVQRSPWLVMRLGILGRGLQEYQLPYQRVLPLPIFTPTKVGASKEEREETPIQLRELLALETALGGQCVERQDVAEITKQLPPVVPVSKPGPLRRTLS---RSMSQEAQRG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15273-1", "uniprot_id": "TELT_HUMAN", "id": "O15273-1", "name": "Telethonin", "aln": "-------------------------------------------------------------------------------------------------MATSELSCEVSEENCERREAFWAEWKDLTLSTRPEEGCSLHEEDTQRHETYHQQGQCQVLVQRSPWLMMRMGILGRGLQEYQLPYQRVLPLPIFTPAKMGATKEEREDTPIQLQELLALETALGGQCVDRQEVAEITKQLPPVVPVSKPGALRRSLS---RSMSQEAQRG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P8J3-1", "uniprot_id": "A0A8M9P8J3_DANRE", "id": "A0A8M9P8J3-1", "name": "", "aln": "----------------------------------------------------------------------------------------MHCLSRTPRSYLLNSYSDLQETDELSRESYEATWLDLLMETRPEYKMTLAEKDSMKKESYESKQVVHFTVRRFPNQTIQMGRDREPMQEYRLPYKNILPIPIFVPRDVTQPDVTRSPSPS-VKSSTDTEASLSGVCLHKREISSITEHKPMVIQPRSPDFRASSLISPPRDTLRFQRRE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .::.* : **:: * * ** :.**** :* *:*: ::*:*. : : *:* * :::* . :***:***:.:**:***.* .: .. *. :* ::. *::*.* *:.:::::.**:: * *: .*. :* *. : :* ", "identical_positions": 46, "similar_positions": 60, "identity": "17.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-940", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZXN3-1", "uniprot_id": "D3ZXN3_RAT", "id": "D3ZXN3-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------MCFKSGLRAHLIVPILEWETPAFWTSAEYNTLCFYILFECRVSFLGESWTLRKHECLESGYKGTTKTGLSQTRALAIAVTMSESMESNTQQLDNPEDEEYLMSGSRYSIISSRLRTKFGIKSLAEYTKQSHNPLVLPLLSFLFLAG-------------------------------------------------------------------------------------------------------------------------------------LLLIILVLVSKVPSSE-----------VQDKIYQELMQLKTEVHDG-----------------------------------------------LCQPCPRDWTFFNGSCYFFSKSQRNWHNSITACKELGAQLVIVETDEEQTFLQQTSKTRGP-TWMGLSDMHNEATWHWVDGSPLSPSFAQYWNRGEP-----NNVGDEDCAEFSGD------GWNDLRCDTRIFWICKKVSTSSCTIK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZCF3-1", "uniprot_id": "D3ZCF3_RAT", "id": "D3ZCF3-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRIQQMGSLG-----------------------------FLDRSNIPLVLQLLFLILFAG-------------------------------------------------------------------------------------------------------------------------------------LLVAIVIQVSKIPSSEEVQW----EQTKQEKMYQDLSQLKSEIDS------------------------------------------------LCRLCPWDWTFFNGNCYFFSKSQRDWHNSITACQEMEAQLVTIKSPEEQSFLQQTSKKNGY-TWMGLSDLNKEGEWYWLDGSPLSDSLRNYWNEGQP-----NNIDGQDCVEFRND------GWNDAKCDNWKFWICKKTATT-CSSK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZP17-1", "uniprot_id": "D3ZP17_RAT", "id": "D3ZP17-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSESKETGKQQLGPLDEELLTSSHTRYSMKGFGFQPNSGFSSFTGYLVHSHVPLALKALFLTVFSV-------------------------------------------------------------------------------------------------------------------------------------LLVVILVKVYKIPSSHEQ------EESNQKNFYQELIQLKAGVDR------------------------------------------------LCRSCPWDWTAFQGNCYFFSVAQKSWNDSATACHNVGAQLVVIKSEEEQNFLQKTSKKRGY-TWMGLIDINKESTWHWVDGSPLTLTFMKYWNKGEP-----NNVGDKDCAEFRED------GWNDTKCDNKKFWICKKPETS-CSSK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LKH2-1", "uniprot_id": "A0ABK0LKH2_RAT", "id": "A0ABK0LKH2-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGDSEEDRVQQLSSLDEEHLIASSTRYSLQGFRFQPPYILKKAAGYLCHGLVPFVLQLICLTLCAI-------------------------------------------------------------------------------------------------------------------------------------LLLAILIKVSNVAYSQGQ------EQAKKEKVYQDVAQLKPQINH------------------------------------------------LCRPCPWDWTFFQGNCYFFSKFQQNWKDSVTSCRKLGAQLVVVKSDDEQSFLQQTSKEKGY-AWMVLSDLKREGIWHWVDGSHLLFSFTKYWNKGEP-----NNEWEEDCAEFRGD------GWNDAPCTNKKYWICKKSALS-CTGK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1LM87-1", "uniprot_id": "F1LM87_RAT", "id": "F1LM87-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------MQPLDSMGEAGLGFWEHEDGEMEVSGSRYSIKSSRLRPNSGIKSLAGCLGHNQAPLVLQLLSFLFLAGLLLIILFQVFKTTNTQWQEEPKQEKILEELNQLTDELMSRIPISQGQNESMQEKISEQLTQLKVELLSRIPVFQVQNES----------------------------------------------------------------------------------------------------------------------------MQEKISEQLTQLKAELLSKIPSLQVQ------DESKQEKIYQQLVQMKTELLR------------------------------------------------LCRLCPWDWTFLLGNCYFLSKSQRNWNDAVRACKEEKAQLVIINSDEEQTFLQLTSKAKGP-TWMGLSDLKNEATWLWVDGSTLSSRFQKYWNRGEP-----NNIGEEDCVEFAGD------GWNDSKCELKKFWIFKKSATA-CTEG------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6A230-1", "uniprot_id": "A0A8I6A230_RAT", "id": "A0A8I6A230-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQCQVREGPNLEG-----------------------------LRRCMIMCIQAF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------IYPDPP---LPIDS------------------------------------------------LCRPCPWEWTFFHGRCYYFSKSQRNWNDSVAACQEVDAQLVTVESDEEQTFLDTFLKNKGP-AWMGLSDLKQESTWQWVDGSPLSDSFRKYWIKGEP-----NNQGNEDCAELRED------GWNDNKCDNKKFWICKKPETS-CSSK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1M698-1", "uniprot_id": "F1M698_RAT", "id": "F1M698-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGKPELHQPNNHEEEVTLED-----HDPEGLICSSKSLQGHLTRAPWLLPLLISLGLFLLMLATLVQISRI----------------------------------------------------------------------------------------------------------------------------CANPQGQTQDQKGSSSFGKVAVPQEQTYTGLEQIQQIQ---QQLTQFNASLAG------------------------------------------------LCRPCPWDWEFFQGSCYLFSRTLASWGASASSCKDLGAHLVIVNSVAEQQFLKYWHIRQSQLTWIGLSDHQREGSWQWVDDTPLKLS---FWKEGEP-----NNAGDEDCVVIAED------KWNDSTCSANNFWVCEQPSTP-CPGHARSALP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1LYU9-1", "uniprot_id": "F1LYU9_RAT", "id": "F1LYU9-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------MGLYKSQVRGKEETGSPEKQKMAGKPELHQLNNHEEEVTLEDQGFAENDPEGLICSSKSLQGHLTRAPWLLLLLISLGLFLLMLAILVQVSRI----------------------------------------------------------------------------------------------------------------------------CANPQGQTQDQKGSSSLGKVAVPQEQTHTGLEQIQQIQQIQQQLTQFNASLAG------------------------------------------------LCRPCPWDWEFFQGSCYLFSRTLASWGASASSCKDLGAHLVIINSVAEQRFMKYWNVRKNQRSWIGLSDHLREGSWQWVDHSPLKFS---FWKEGEP-----NNDGDEDCVELFMD------EWNDNTCTQQNFWVCEQPSAP-CPGHGRSVLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N1N0-1", "uniprot_id": "CLC4F_HUMAN", "id": "Q8N1N0-1", "name": "C-type lectin domain family 4 member F", "aln": "-----MDGEAVRFCTDNQCVSLHPQEVDSVAMAPAAPKIPRLVQATPAFMAVTLVFSLVTLFVVVQQQTRPVP--KPVQAVILGDNITGHLPFEPNNHHHFGREAEMRELIQTFKGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKVYY--WIGLTDRGTEGSWRWTDGTPFNAAQNK-------------APGSKGSCPLRKY------IIVNSGMG-ACSFIDTPPCPWILSN-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70194-1", "uniprot_id": "CLC4F_MOUSE", "id": "P70194-1", "name": "C-type lectin domain family 4 member F", "aln": "MKEAELNRDMARYCTDNQCVSLQPQGLGPKSAALMAPRTLRHVQVILALMVVTVIFSLLALFVVASQPWRPEWNKEPPSLLLRGSNNSGH-----DNHSQFVRETEMQVAIQRLRDYEENSSSCHKEVQILKYQMDNVSSLVQLLGSHLEDVNADILQTKDVLKESGALALETQALRSSLEVASADIHSLRGDLEKANAMTSQTRGLLKSSTENTSAELHVLGRGLEEAQSEIQALRGSLQSAN-----------------------------------------------------------DLSSQTQGFLQHSMDNISAQIQTVRDGMERAGEKMNSLKKELETLTAQTQKANGHLEQTDAQIQGLKAELKSTSSLNSRIEVVNGQMKDASRELQTLRRDLSDVSALKSNVQMLQSNLQRAKTEMQTLKADLQATKALTAKIQGEQNRLGALQEAVAAQKQEQKTQNQVLQLIAQNWKYFNGNFYYFSRDKKPWREAEKFCTSQGAHLASVTSQEEQAFLVQTTSSGDH--WIGLTDQGTEGIWRWVDGTPFNNAQSKGFWGKNQPDNWRHRNGEREDCVHVRQ------QWNDMACGSSYPWVCKKSTGWSAARVG-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32TFP3-1", "uniprot_id": "A0AB32TFP3_DANRE", "id": "A0AB32TFP3-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------MTSGIEMAQPIYGNILVNYDPTPKMDRCSLRNETASDSGKKRSSRAAPVCLVLLCLLLLTAVIVLSVFIYTNNTNFAEERRQLITNIANITEDRDK-----------------------------------------------------------------------------------------------------------------------------LLTDIINLTKIKDKVLINITNLEEDRDELLNKITTFTKARNEILKKNANLLKD------------------------------------------KDQLIKQLQVFGQEAYYQSSFYYLSSERKSWTESRRDCKDRGADLIIINNKQEQDFIMKITSNNEF--WIGLTDSDKEGIWKWVDGSNLTSRFWASSGSITEP----NGRKTENCAVTHLKKHPELIGWLDVACDGAYQWICEKNILPVTS--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . * :* * : * . *.* : . ** *: *: * * *. * * * : : . : :: . ", "identical_positions": 16, "similar_positions": 19, "identity": "2.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-945", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P86410-1", "uniprot_id": "RLGPB_RAT", "id": "P86410-1", "name": "Ral GTPase-activating protein subunit beta", "aln": "MYSEWRSLHLVIQNDQG---HTSVLHSYPESVGREVANAVVRPLGQALGHSPVSASQSLLYTDKDVKWTMEVICYGLTLPLDG-ETVKYCVDVYTDWIMALVL-PKDSIPLPVIKEPNLYIQSILKHLQNLFVPRQ-------------EQGS-SQIRLCLQVLRAIQKLARESSIMARETWEVLLLFLLQINDILLAPPTVQGGIAENLAEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVICALTSRLLRFTYGPSFPPFKVPDEDANLIPPEMDNECIAQTWFRFLHMLSNPVDLSNPAVISSTPKFQEQFLNVSGMPQELSQYPCLKHLPQIFFRAMRGISCLVDAFLGISRP-------------------------------RSDSAP-----------------------------------------------------------------------PTPVNRLSMP----------------------------------QSAAVNTTPPHNRRHR-------AVTVNKATMKTSTVTTAHTSKVQHQASSTSPLSSPNQTS-------SEPRPLP------------------------------APRRPKVNSILNLFGSWLFDAAFVHCKLHNGINRDSSMTASFIQILLSYKSSIATQASMEFRRKGSQMSTDTMVSNP-VFDASEFPDNYEAGRAEACGTLCRIFCSKKTGEEILPAYLS-----------------------SVILNSPPLFCCDLKGIDVVVPYFISALETILPDR--ELSKFKSYVNPTELRRSSINILLSLLPLPHHFGTVRSEVVLEGKFSNDDSSSYDKPITFLSLKLRLVNILIGALQTETDPNNTQMILGAMLNIVQDSALLEALG--------CQMEMG---GGENNLKSHS--RTNSGISS--------------ASGGSTEPTTPDSERPAQALLRDYGS-T----------DSAAGLLIRSIHLVTQRLNSQWRQDMSISLAALELLSGLAKVKV-MVDLGDRKRAISSVCSYIVYQCSRPAPLHSRDLHSMIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKN-SEQEVKYKGDKEPNPASMRVKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSR--LPTINKHS------FRYFVLDNSVILAMLEQPLGNEQNDFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKANQK-LFVPEPRPVPKNDVGFKYSVKHRPFPEEVDKIPFVKADLSIPDLHEIVTEELEERHEKLRSGMAQQIAYEMHLEQQSEGELQKRSFPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALK--EPANSRLPP---HLIALDSTIPGFFDDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNV--ESSRNVQPHFLEFLLSLGWSVDVGRHPGWTGHVSTSWSINSCDDGEGSEQDEVTSSEDVGASIFNGQKKVLYYADALTEIAFVVPSPVESLTDSLESNISDQDSDSNMDLMPGILK-QPPLTLELVPNHTDSLNSSQRLSPSSRMKKLPQGR-------PVPPLGPETRVSVVWVERYDDIENFPLSDLMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTALFQEVGLKNCSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BQZ4-1", "uniprot_id": "RLGPB_MOUSE", "id": "Q8BQZ4-1", "name": "Ral GTPase-activating protein subunit beta", "aln": "MYSEWRSLHLVIQSDQG---HTSVLHSYPESVGREVANAVVRPLGQALGTSSVAGSESLLKTDKEVKWTMEVICYGLTLPLDG-ETVKYCVDVYTDWIMALVL-PKDSIPLPIIKEPNLYVQSILKHLQNLFVPRQ-------------EQGS-SQIRLCLQVLRAIQKLARESSIMARETWEVLLLFLLQINDILLAPPTVQGGIAENLAEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVICALTSRLLRFTYGPSFPPFKVPDEDANLIPPEMDNECIAQTWFRFLHMLSNPVDLSNPAVISSTPKFQEQFLNVSGMPQELSQYPCLKHLPQIFFRAMRGISCLVDAFLGISRP-------------------------------RSDSAP-----------------------------------------------------------------------PTPVNRLSMP----------------------------------QSAAVNTTPPHNRRHR-------AVTVNKATMKTSTVTTAHTSKVQHQASSTSPLSSPNQTS-------SEPRPLP------------------------------APRRPKVNSILNLFGSWLFDAAFVHCKLHNGINRDNSMTASFIQILLSYKSSIATQASMEFRRKGSQMSTDTMVSNP-VFDASEFPDNYEAGRAEACGTLCRIFCSKKTGEEILPAYLS-----------------------SVILNSPPLFCCDLKGIDVVVPYFISALETILPDR--ELSKFKSYVNPTELRRSSINILLSLLPLPHHFGTVRSEVVLEGKFSNDDSSSYDKPITFLSLKLRLVNILIGALQTETDPNNTQMILGAMLNIVQDSALLEAIG--------CQMEMG---GGENNLKSHS--RTNSGISS--------------ASGGSTEPTTPDSERPAQALLRDYGS-T----------DSAAGLLIRSIHLVTQRLNSQWRQDMSISLAALELLSGLAKVKV-MVDSGDRKRAISSVCSYIVYQCSRPAPLHSRDLHSMIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKN-SEQEVKYKGDKEPNPASMRVKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSR--LPTINKHS------FRYFVLDNSVILAMLEQPLGNEQNDFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKANQK-LFVPEPRPVPKNDVGFKYSVKHRPFPEEVDKIPFVKADLSIPDLHEIVTEELEERHEKLRSGMAQQIAYEMHLEQQSEGELQKRSFPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALK--EPANSRLPP---HLIALDSTIPGFFDDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNV--ESSRNVQPHFLEFLLSLGWSVDVGKHPGWTGHVSTSWSINSCDDGEGSEPDEITSSEDVGASIFNGQKKVLYYADALTEIAFVVPSPVESLTDSLESNISDQDSDSNMDLMPGILK-QPPLTLELVPNHTDSLNSSQRLSPSSRMKKLPQGR-------PVPPLGPETRVSVVWVERYDDIENFPLSDLMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTALFQEVGLKNCSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86X10-1", "uniprot_id": "RLGPB_HUMAN", "id": "Q86X10-1", "name": "Ral GTPase-activating protein subunit beta", "aln": "MYSEWRSLHLVIQNDQG---HTSVLHSYPESVGREVANAVVRPLGQVLGTPSVAGSENLLKTDKEVKWTMEVICYGLTLPLDG-ETVKYCVDVYTDWIMALVL-PKDSIPLPVIKEPNQYVQTILKHLQNLFVPRQ-------------EQGS-SQIRLCLQVLRAIQKLARESSLMARETWEVLLLFLLQINDILLAPPTVQGGIAENLAEKLIGVLFEVWLLACTRCFPTPPYWKTAKEMVANWRHHPAVVEQWSKVICALTSRLLRFTYGPSFPAFKVPDEDASLIPPEMDNECVAQTWFRFLHMLSNPVDLSNPAIISSTPKFQEQFLNVSGMPQELNQYPCLKHLPQIFFRAMRGISCLVDAFLGISRP-------------------------------RSDSAP-----------------------------------------------------------------------PTPVNRLSMP----------------------------------QSAAVSTTPPHNRRHR-------AVTVNKATMKTSTVSTAHASKVQHQTSSTSPLSSPNQTS-------SEPRPLP------------------------------APRRPKVNSILNLFGSWLFDAAFVHCKLHNGINRDSSMTA------------ITTQASMEFRRKGSQMSTDTMVSNP-MFDASEFPDNYEAGRAEACGTLCRIFCSKKTGEEILPAYLSRFYMLLIQGLQINDY-VCHPVLASVILNSPPLFCCDLKGIDVVVPYFISALETILPDR--ELSKFKSYVNPTELRRSSINILLSLLPLPHHFGTVKSEVVLEGKFSNDDSSSYDKPITFLSLKLRLVNILIGALQTETDPNNTQMILGAMLNIVQDSALLEAIG--------CQMEMG---GGENNLKSHS--RTNSGISS--------------ASGGSTEPTTPDSERPAQALLRDYALNT----------DSAAGLLIRSIHLVTQRLNSQWRQDMSISLAALELLSGLAKVKV-MVDSGDRKRAISSVCTYIVYQCSRPAPLHSRDLHSMIVAAFQCLCVWLTEHPDMLDEKDCLKEVLEIVELGISGSKSKN-NEQEVKYKGDKEPNPASMRVKDAAEATLTCIMQLLGAFPSPSGPASPCSLVNETTLIKYSR--LPTINKHS------FRYFVLDNSVILAMLEQPLGNEQNDFFPSVTVLVRGMSGRLAWAQQLCLLPRGAKANQK-LFVPEPRPVPKNDVGFKYSVKHRPFPEEVDKIPFVKADLSIPDLHEIVTEELEERHEKLRSGMAQQIAYEIHLEQQSEEELQKRSFPDPVTDCKPPPPAQEFQTARLFLSHFGFLSLEALK--EPANSRLPP---HLIALDSTIPGFFDDIGYLDLLPCRPFDTVFIFYMKPGQKTNQEILKNV--ESSRTVQPHFLEFLLSLGWSVDVGRHPGWTGHVSTSWSINCCDDGEGSQQ-EVISSEDIGASIFNGQKKVLYYADALTEIAFVVPSPVESLTDSLESNISDQDSDSNMDLMPGILK-QPSLTLELFPNHTDNLNSSQRLSPSSRMRKLPQGR-------PVPPLGPETRVSVVWVERYDDIENFPLSELMTEISTGVETTANSSTSLRSTTLEKEVPVIFIHPLNTGLFRIKIQGATGKFNMVIPLVDGMIVSRRALGFLVRQTVINICRRKRLESDSYSPPHVRRKQKITDIVNKYRNKQLEPEFYTSLFQEVGLKNCSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ATR5-1", "uniprot_id": "A0A8M3ATR5_DANRE", "id": "A0A8M3ATR5-1", "name": "Ral GTPase-activating protein subunit beta", "aln": "MYSEWRSLHLVVQSDQG---HLSVLHTYPAGVGRDVANAVVRPLGNSLGG---VPSECLLKTDKEVKWTMEVLCYGLTLPLDG-DTVKLCVDVYTDWIMALVS-PRDSIPQPIIKEPDLYVQTILKHLHNLFLPRP-------------ENFSLVHFKLCQQVLSAVQKLARDSSSMARETWEVLLLFLLRINDTLLAPPTVGGGLAEKLAEKLISVLFEVWFLACTRCFPTPPYWKTAREMLANWRHHPPVVEQWSKVIAALTSRLLRFMYGPSFPPFKVPEEDASLIPAEMDNDCVAQTWYRFLHMLSNPVDLSNPVIVSSTPKFQEQLLGVNSVPHEVIQHPCLKQLPQIFFRAMRGISCLVDAFLGISRP-------------------------------RSDSAP-----------------------------------------------------------------------PTPVNRLSMPP---------------------------------PPTTTNTTPPHNRRHR-------PTAVAKTTSKSSTTG---QTRVSHQPSSTSPLSSPNQTS-------SEPRPLP------------------------------APTRPKVNSVLNLFGQWLFDAALVHCKLHSGLSRDSSMTA------------LATQAGVELRRKGSQMSTDTMVSNP-MFDANEFPDNYESGRAEACGTLCRIFCSKKTGEEILPVYLSRFYMVLIQGLQISDF-ICRPVLASIILNSSALFCSDLKGINVVVPYFISALETILPDR--ELSKFKSYVNPTELRRASIHILLSMLPLPHHFGNVKSEVLLEGKFSNDDNSLHDKAVTFLSLKLRLVNILIGALQTETDPINTQMILAAMLNIVQDSALLESVG--------AQAEVGSVDGSHSLAKSHS--RNNSGISN--------------ASAGSSEATTPDSERPAQALLRDYDT--------------AAGLLIRSIHLLTQRLNSQWRLDMSISLAALELLAGLAKVKV-SVESSDRKRAVSSVCSYIVYQCSRPAPLHSRDLHSMIVAAFHCLCVWLTEHPDMLNEKDCLIEVLEIVELGISGSKSKT-GEQEVKYKGDKEHNPASMRVKDAAEATLSCIMQVLGAFPSPSGPASPCSLLNEDTLIKYSR--LTSTSHSN------FRYFVLDNSVILAMLEQPLGNEQN-PCPSVTMLIRGMSGRHAWTMQLFHQPRGARANQKQVFVPESRPTPKNDVGIRFNVKHRPFPEEVDKIPFVKADLSIPDLHDIVDKELEQQHDKLRVVMGKQIDYETKLEHHTEDLWRNKAFPDPLTDCKPPAPAQEFQTARLFLSHFGFLSLEALK--EPGNSRLPP---HLIALDSSVPGFFDDVGYLDLLPSRPCDTVFIFYMRAGQKSSQEILKNV--ESSANVQPHFLELLLSLGWPVEVAQHPGWTGSVFTSWTINTSN-GADTPDDSVTLG-DTGGGVFNGEKQVLYYADALTEIAFVVPSLSDSSAESSEHSFPTADSDSQMELLPSLLK-QPNLTLELFPNHSDNMGPAQR-SPTAKNKKLPPGR-------TIPPLGPDTKVLVVWVERYDDIENFPVSELLAETSTGVETAVNSSAS-RSSSSEKDVPIVFIHPLKTGLFRIKLQGALGKFNMVIPLVDNMVVSRRSLGFLVRQTVINACRRKRLESDSYSPPHVRRKQKIAEIVNRYRNKQLEPEFYTSLFLEVNETSLKP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JEC6-1", "uniprot_id": "X2JEC6_DROME", "id": "X2JEC6-1", "name": "Rap-GAP domain-containing protein", "aln": "MYSEWASLSAQITANSCGAQCFSVLNKFPASAGREVVVSVVKQLGTNLGITQNAEPSHLVK-DEEVKWCMDVICFGLSLPLQEHETIKDCVNVYCEWLTALHPQPRISVPKPICEDANLYARQIINHFHNLFVPRQGEILPFLYQTTLGADTIKRQAVLCHRVLRTLQQTAQISQLMDRQTWDTLLLFLLAINEILLAPPTVKDDVGDQLCERVLSVLFEVWLLACVRSFPSPSMWKTLQESCAMWRHRVALVDQWNRVNLALTARLLEFSYGPAFPQLKNADEDGQLIPIGMSNDCVAQTWYRFLRMIGNPTALCSPHIISKSSHFVQWALTHEKG-AETHQHPCLQQLPQIFLNAMKGISSQVDAFLGVYQPPPQQTDGVVTNLLEIRHSLNEATSSTLQQFIHSSSATNIANQQNQPAHHHHHLHYPHLHLHGAGSFLRDNFMSNSASSALNAIMGHHGGHHGHHHQQQQQQQQQLQISASPTSSLTTSGSSAVGSTSAGGSHSAGVVGSISFGATESPGPGQASASATPTPPLQRRLAKSFSVAPTITQQKGLSKTSLIGLTGGGARNAISSSSTTTTNAGSTGGTGSGDGSAPAPLPTTPTSTSGPPSASSSINSLPLTSMGAGVELAVARPKCNSILHVFHEWLFEAAHIGGDTWRQNRKKQACEAS----------KRPSSMIMEHRKGSISLSQPNSLNDPQSLPPTLTIDKYESGRAEAIGTLCKIFCAKKTGEEILPVYLARFYMALQQCLKITESRECDETLASILLHSSDLFRLDLDGINVLLPGFIAALEIVLPDKDLKLKTQSMVFNRTELRRSAINILLSIMVLPLHYQTLP--------IRDLTCESSEKMFTFIQLKSRLMNILMNALQVETDAQNTHMLLGGLLLCVQDAVTFEETELGGGNANLSQNSSGVQHHDANLLSSACSERSASLVSAGTASLGGQTTATMGAGSGSIRDTASAHDYPSLTISDDMSFEFGQELEGVTTYDNAHALFVRATYLVCHRLISSWKTDLNVSLAALELLSGLARLHIRETDALECKRAVKWICDYICYQCSRPPPAHSKDLHSTIVAAFQCTAAWLMQHPYLLQDKDCLQTVLEVVELGISGTKSQSKGTDIPKFKDEKELKPASMRVRDAAENLLTIILEQVGYFPSECGPESISSLLDELALMKHCNSMVPAAAASSEQAIAKFKYFVTENSTILALLEEPLGNDQD-PQPTVTLLIRGPFGRHAWTMQLRHLPR-SKSGIKYHAINPGRPIPMNDVTQRLDSEQKNFPDGVDKVQPCVADYSIPTIEQMREQYGTAVIRELESLLENQSIHEKLAWAEADTSADSLSH---AQECVPPTVCHEFHAARLFLSHFGFLGFETRNPQNPAEALGNPPQRPLIVLDTKSAAFAADLDRLDKLSARTHDSVYVFYVKSGQTSAQQIIANMGEESSASHDPHFASMLQTLGWPVQVSEHSGWTGFAHNSWSL------KGTPEEQLKSTANELN--YNGSQRVLYWADVSSEIAFVVPTTWNLRYNSDTCDSGSISSTDQIGSSNVWTRGEADSAAGLAKSKSRNLSLELDTNRRDVKEPVPPTRRKGNVTKPTLLAQAPAKIFLVWLESYEDYLNFPLEDLLAYTRTGEELQT------QQLPRASDCHVIFVHSLLSGLLRVKLQGPPGRMSFATPLVDGMVLSRRVVGNLVRQTALNISRRRRLDNDNYQPPHVRRRLKVQDIVQKYKMDLSEADLLAHLFQRAI------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** ** : :. ***:.:* ..**:*. :**: ** ** .. *: *::*** *:*:*:**:***: :*:* **:** :*: ** *: *:* *: ::.: * : *::*::***:** : : ** :** ::*: *: *. * *:**:.****** **: ******* ..:.::*.*:::.******:***.*.**:*. *** :* * ***: .:*:**.:* ***:***.* ***:** :* .:**..*** *.*:*:****:***:*:.**. *..* ::*.:.:* : * . * *:***::*****:.**:***. ******: :* :*.**. .:*.. *: . .::...*** :** . : * *:* . .**::. :....*. * * *** * *** **:*::* .***:** : . :..: * .:. :* *: . .:* . :.:* : .. *:**:***** ****:***:*********.**: *::*:*. ** **.**:*::* **:*** :***: :*.. . .* *****::*:****:: ** *: .: : : . :* .**:.** **:***:.***.***. **:*:*..:* ***:. :* .* . * . . .* . *. * :* *..** . *:. : *: :: * * .*::*: :*: :** *.*: *:.:********:***:::: .: : ***:. :* ** ******.* **:**** *****:* ..** :** :*::**** ***:*******:**:. . : *:*.:** :******:**** *: *:: :* *** .** * .**::* :*:*:.. :.: . *:*** :**.***:**:****:*: *:**:*:** ** **: ** ** :::. * : ** * *** : . ::: **: ***: ** *** :.:: : :*. : :* :* .:: . :. :* **. .:**::***********.:*: : :*.:: * **.**:. ..* *:. ** *..*. *:*::**::.**.: *:*: *: *** . :*** .:* :***.*:*..*.**** . .**:: .: .: : :**.::***:**. :*******: : :* . .* .:: : :. : * .:: .:. . . :* * . . ::: :**:* *:* ***:.:*:: ** * . :. . .: ::*:*.* :**:*:*:**. *::.:. ****.*::*** :* *****.:* .**:**:.*.*.******: *: :**::*: . *.:: : ** .. ", "identical_positions": 577, "similar_positions": 472, "identity": "32.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-951", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A1F6-1", "uniprot_id": "A0A8I6A1F6_RAT", "id": "A0A8I6A1F6-1", "name": "NHS-like protein 2", "aln": "MPFYRRTVVPQRLCPRNPPQPLAELRDVSHLAALSLLRQLADLCGHSLALLEDLEGHLLALGRRTDSLYRRTVRLRRRLPCRLLGPEDDEELQAAANSGRENATATAHSRSSWRQPVNVFLSSGRPPSVEELLREAQLNLQSLLQEEYEEQYSEARLLGQTFR------SSDEAPEPTPSPRPQSAKRLEFVLMPAKWQLSEDETTTQGVRAPEACLSLCT-ADKQIAWNRPFPLPILKEKRWLQSCSIQSDLVPINTSGQQFDRHASFR---HSLFNTETAVNPKSTLRRRRTIIGFSNFSQRDQGHSSSPTGSLAHSATSDIRPGHPAPQVVQGRVAVGQEARFPSLTSPGLRHSSSEPGDTHQARSGPDPPSMESMAVVYSVPSSCNGPTESTFSASWKGDAFTYMTPSASNQGNQVSENGKNPSSGNS---WVPLNTLP--PLVPKEAATLFVTRDNPAG---CPGLPSYSEHPTLRRQIPERPPKIGLLPRGASRLETGPGGTN--RFRERSLSVPTDSG---VTSVDYDEEQKVN-----EARILPYASTSSEGSNSTDNIAALSTEQEARHR--RQRSKSISLKKAKKKPSPPMRSVSLVKDEPAVPPEGELVLP---KDQRPRSLCLSLEHQG--------HHPPHPDAQGHPAVPTFKDPEG-------TQFSHHWYLTDWKSG-DTYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREVASPGRPTGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSTSVRVRPVVPERKSSLPPTSPMEKICKSRLSFDLPLTSSTTLDLSGMSISIRSKTKVSRYHSDTNFGAKLVQKTSPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIE-SPDYTEEPG----AEEVFTLPERKVKPPIAEKPPLARRPPSLVHRPSSLPGEYPLTSPTMAMTPRSSIPHMKQLPQDSYTVLRKPKSPSFPVGRSPGESTAASSLVFSPLASSSGAFFSG----TQQPPQASVEDGDPKVRALPERISLQSQEEAEKKMTKIPPPVPKKPSVLYLP---------------LTSPVAQMDACMAEPRLPFSPIITLEEDAKCPSTGDD-------QKSPGKR-----VTSTLHIDR------EKEATSPGRSVEPSAEEKSLIS-----DKTAEWIAED-DDDVFVAS---RTTEDLFTVIHRSKRKLLGWKETGEGFTGSRPSSHSPVKNTAESPTGESAAAPGPSGSACLDAGRNDDFKALLQKKGSKATPRTRPSAAELLKSTNPLARRIIAQFSKDYEP----TDNPST---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AXH1-1", "uniprot_id": "NHSL2_MOUSE", "id": "B1AXH1-1", "name": "NHS-like protein 2", "aln": "MPFYRRTVVPQRLCPRNPPQPLAELRDVSHLAALSLLRQLADLCGHSLALLEDLEGHLLALGRRTDSLYRRTVRLRRRLPCRLLGPEDDEELLAAANSGRENATATAHSRSSWRQPVNVFLSSGRPPSVEELLREAQLNLQSLLQEEYEEQYSEARLLGQTFR------SSDGAPEPTPSPRPQSAKRLEFVLMPAKRQLSEDETTTQGVRAPEACLSLST-ANKQSAWNDPFPLPILKERLWLQPCSTQSDLVPINISGQQFDRHASFR---HSLFNTETAVNPKSTLRRRRTIIGFSNFSQRDQGHSSSPTGSLARSATSDIRPGHSAPQVVQGRVAVGQEARFPSLTSPGLRHSSSEPGDAHQARSASDHPGMESMAVVYSVPSSCNGPTESTFSTSWKGDAFTYMTPSASSQGNQVSENGKNPSSGNS---WVPLNTLP--PLVPKEAATLFVTRDNPAG---CTGLPSYSEHPTLRRQIPERPPKIGLLARGTSRLETGPGGTN--RFRERSLSVPTDSG---VTSVDYDEEQKTS-----ETRILPYASTSSEGSNSTDNIAALSTEQEARHR--RQRSKSISLKKAKKKPSPPMRSVSLVKDEPALPPEGELVLP---KDQRPRSLCLSLEHQG--------HHPPHPDAQGHPAVPMLKDPGS-------TQFSHHWYLTDWKSG-DTYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREVASPGRPTGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSASVRVRPVVPERKSSLPPTSPMEKICKSRLSFDLPLTSSTTLDLSGMSISIRSKTKVSRHHSDTNFGVKLAQKTSPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIE-SPDYIEEPG----AEEVFTMPERKVKPPIAEKPPLARRPPSLVHRPPSLPGEYPLTSPTMAMASRSSIPHMKQLPQDSYTVLRKPKSPSF-----PGESTASSSLVLSPLASSSGAFFSG----TQQPPQASVEDGGPKVRALPERIGLQSQEEAEKKMTKIPPPVPKKPSVLYLP---------------LTSPVAQMDACMAEPRLPFSPIITLEEDGKCPSTGDD-------QKSPGKG-----VTSPLHTDT------EKEAISPGRSVEPSAEEKSLIS-----DKTAEWIAEE-EDDVFVAS---RTTEDLFTVIHRSKRKLLGWKETGEGFTGSKPSSHSPVKNTADSPTGEAAAAPGPSSSACLDAGRNDDFKALLQKKGSKATPRTRPSAAELLKTTNPLARRIIAQFSKDYEP----TDNPST---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5HYW2-1", "uniprot_id": "NHSL2_HUMAN", "id": "Q5HYW2-1", "name": "NHS-like protein 2", "aln": "MPFYRRTVVPQRLCPRNPPQQLAELRDVSHLAALSLLRQLADLCGHSLALLEDLEGHLLALGRRTDSLYRRTVRLRRRLPCRLLGPEEDEEELAAANSGRENATATAHSRSSWRQPVNVFLSSGRPPSVEELLREAQLNLQSLLQEEYEEQYSEARLVGQTFR------SSDEATKPTPNPRPQSARRLEFILMPTKRQLSEDETTTQGVRAPEASLSLSTTADKQTAWNSLFPLPILEEKRWPQLCSTQSDIVPINISGQQFDKHASLR---HSLFNTETAVNPKSTLRRRRTIIGFSNFSQRDQGHSNSPAGSVAHSTTSDIRPSHSVPEGVHGRVAVGQDARFPSLTSPVLRTPSSEPDEPHQARSGPNPPGMESMGMVYSVPSSCNGPTESTFSTSWKGDAFTYMTPSATSQSNQVNENGKNPSCGNS---WVSLNKVP--PLVPKEAATLLVARDNPAG---CSGSAGYPERLIQQRHMPERPSKIGLLTSGTSRLETGPGGAS--RFRERSLSVPTDSG---TTDVDYDEEQKAN-----EACALPFASTSSEGSNSADNIASLSAQQEAQHR--RQRSKSISLRKAKKKPSPPTRSVSLVKDEPGLLPEGGSALP---KDQRPKSLCLSLEHQG--------HHSSHPDAQGHPAIPNHKDPES-------TQFSHHWYLTDWKSG-DTYQSLSSSSTATGTTVIECTQVQGSSESLASPSTSRATTPSQLSIEVEAREISSPGRPPGLMSPSSGYSSQSETPTPTVSMSLTLGHLPPPSSSVRVRPVVPERKSSLPPTSPMEKFPKSRLSFDLPLTSSPNLDLSGMSISIRSKTKVSRHHSETNFGVKLAQKTNPNQPIMPMVTQSDLRSVRLRSVSKSEPEDDIE-SPEYAEEPR----AEEVFTLPERKTKPPVAEKPPVARRPPSLVHKPPSVPEEYALTSPTLAMPPRSSIQHARPLPQDSYTVVRKPKPSSFPDGRSPGESTAPSSLVFTPFASSSDAFFSG----TQQPPQGSVEDEGPKVRVLPERISLQSQEEAEKKKGKIPPPVPKKPSVLYLP---------------LTSPTAQMEAYVAEPRLPLSPIITLEEDTKCPATGDD-------LQSLGQR-----VTSTPQADS------EREASPLGSSVEPGTEEKSLIS-----DKTAEWIAED-DDDVFVAS---RTTEDLFTVIHRSKRKLLGWKEPGEAFVGGRTSSHSPIKNTAESPISESTATAGSGSSANLDAGRNDDFKALLQKKGSKATPRSRPSAAELLKTTNPLARRIIAQFSKDYET----TDNPST---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AUJ8-1", "uniprot_id": "A0A8M3AUJ8_DANRE", "id": "A0A8M3AUJ8-1", "name": "", "aln": "MPFCKRTIVPKDVS-RSRGAVLTDLVDVCGLTLCAVLRQLSDLSRQSVSILEELEGELASICYRSGALENKLTSLQKHIAALATKPPAKTATNLDSESKR-----TAHFQSSWQQHVNVFGSWSRPECVQELHQEAQLNLQSLLQD-FEEQLYDNRVTGQTFKHPSSQSSEDTSTTLSRSPSSLNNKKTEFVFVPANKQVCEDETTTLGVRAQDP--SPCASEKTLLGWNAALSPPVAEKPRWYLGRQTPAQLVPIEITGQSFDKHAARHSELRATIRTDSAVNPK-TIRRPRSVVAGPDVTLHCQGDSKILAVDLIQGACS---PGSSQPRSLEPTTENTGQQHIP------LRKTQSDLEYSIPP-SPKTPSGMMDHATLMCPSPSWNGPKGSTFSPSWN-DSYNYALVTSPASKQPVTKTGMLTPGGDRGGLICPSQTSSGLSMSSGSHSSSFTSISEPCGHRVYTVSTQGSGVVTGKRNETEVTASTAVTRNSKSEQEKRSARSNVFRFRERSLSTPTDSGSFCSADNICSPGEAVSGVPEGESYALLYPSNSSEDSTSTDNVSVTTGSDFLPDGRLRSRSRSISLKKSKKKPPPPVRSVSLMKNLSEIRGMGSYQNEGHFRDGRPKSLFIPRDIQDSFQPEFLIAKPDDDTDQAHSSLETSSDISQPADRETELGFPPHWQLNEWKSNNDPYRSLSGSSTATGTTVIECMKVRGSSESLNSPSTSRATSPSQMSIEAET--KVSPFKPPCLLSPSSGYSSQSETPTPTISNTLLTG---PSPVGCKMRPKIPERKSSLPAS--AKDKSRSRLSFELPAN--AQLDLS----FVKPKPKASRRHSDTST-ANKPGKLSPSQSSLPMVTTTDLRNIRLRSVSRSELEDSPDGSSDIIEEEQSRDLSPPITPSNTKQPKPPVAMKPPLPKRPVNLTLKSPSS-------SPLTPESPPSSPVDRPMPVGNIYMVVRKPKPKRPAQASLSTSAIATQEPIRSHVSTFPEFDLEHGIPIEEDLPSPSSPEREDKCKTLPSRMTISCLAELDKRKPKVPPPVPKKPSVLLLPSPSIQTNGGAERQTLLSESISQSPTGTSASEIEGDLLKDEEEDYSAKQISHENHQIPELYETFGNEENDVVVEEYSSEDRGSHHFMERETPPAEIVKEIYTETEILEENISAVDKTELHITEETEDEVFVNTPTTHTTEDLFTIIHRSKRKVLGRKEPSDSFGRSQ-CLVSPVKSSSTDFRTLGLGTTPRSSS------RNENFMALLQKRSSKASSGTRVSAMELLKSTNPLARRVTEFSQSQPDGSAMNTPKPSSQDQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** :**:**: :. *. *::* **. *: ::****:**. :*:::**:***.* :: *:.:* .: . *::::.. * . ::* * *** :***:* **** * .** .*:** :***********: :*** : *: ****: *.* :. : .* . . :: **:::*:: *:.****** **** :. * .: .. .** :. *: :: * . :::***: :**.**:**: : :: :.*::***** *:** *:::. .:.: : **.*. : .: :.: * *. . *. :. . : ::* ** ..*: . . * ..* . . : . ..* ***. ****.**: *::.* ::. . : *.:.* .. *: . :. . .: . . :: :.: .:*.* . . . :*: .* ... .: . *. *. .. :. ********.***** :. . : .. *: * :.*.***.*.*:**:: : .: . *.**:****:*:****.** *****:*: . : * :* **:** :. : *. :. . *.*.:: .* *. ** *.:***. *.*:***.************ :*:****** ********:***:***.*: ** :*. *:****************:* :* * *.. . ::** :********.: :. :*****:** . . **** ::.*.*.** **:*. .: * .*.*. :**** :***.:******:** **. : *.: ** : : . :: ***:* ***:.:** .*. :..* ** . .. ** . : * *:****. . .: *... : : .:: . :. :: *. * : * :.**.*: :.. * :*: *:*********** ** *:.. :* : : ..: . : *** .. ..: :: *: * . * *:*: . * :* : * . *** *:*: :*:*** : :*******:*******:** **..:.* .: . **:*.:: . . .:. ..* **::* *****:.***:. :* ** ****:*******: ..: : * :**: ", "identical_positions": 433, "similar_positions": 395, "identity": "32.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-956", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6F6B3-1", "uniprot_id": "TANC1_RAT", "id": "Q6F6B3-1", "name": "Protein TANC1", "aln": "-------------------------------------------------------------------------MLKAVLKKSREGVKGSKKEAGGDFGSETP---TLSSSGDSPVNSLSTTEDTYRVSLAKGVSMSLPSSPLLPRQSHLTQSRANKKSPGPVRKPKYVESPRVPGDPVMIPFREGSKPAEPIETEAKVDNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEDKNEAMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAANKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGS-SLEWNRDGSLR--------LGVQKGVLHDRRLDNCSPVAEEET--TGSAESVLPKAESSAGDGPVPYS-QSSGSLIMPRPN------------------------------------------------------SVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHSTAG--------ARFAPYKPQEILLKPLLFEVP-------------------------------------------------SITTDSVFVG------------------------------------RDWLFQQIEENLRNTELAENR--GAVVVGNVGFG------------------------------------------------KTAIISKLVALSCHGSRMRQVASSSPSSSLKTSDPTHDLPGTPLLSPSSSTSALSAA--------------------------------------------------------------------------------------------------------------------------------------------------------------------RTPPGPGTVDSQRPREDAVKYLASRVVAYHYCQADNTYTCLVPEFVHSIATLLCRSHQLAAYRDLLIREPQLQSMLNLRSCVQDPVAAFKRGILEPLTNLRNEQKIPEEEYIILIDGLNEAEFHKPDHGDTLSSFITKIIPKFPPWLKLIVTVRADFQEIISTLPFVKLSLDDFPGNQDIHSDLHAYVQHRVHSSQDILSNIS----LNGKADAALIGKVSSRLVLRNLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFDRALPILNVALASLHPMTDEQIFQAINAGHI-QGEQGWEDFQQKMEALSCFLIKKRDKTRMFCHPSFREWLVWRADGESTAFLCEPRNGHALLAFMFSRQESKLNRQQTVELGHHILKAHIFKGLSKKTGVSSSHPQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGMSENGMNALCYAAAAGHMKLVCLLTKKGARVDHLDKKGQCALVHSALRGHSDILQYLLNCEWSAGPPQPGTLRKSQALQQALTAAASMGHSAVVQSLLGMAE-EHEIEVNGTDTLWGETALTAAAGRGKLEICELLLERGAAVSRANRRGVPPLFCAARQGHWQVVQLLLDRGCDVNPND-KQGRTPLMVAACEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAEIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTAVVVTLLRKGAKLGNAAWAMATFKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYALRKFP-REGPGEDMRPFNELRVSLYLNLSRCRRKTNDFGLAEEFASKALELKPKSYEAFYARARAKRNSRQFLAALADLQEAVKLCPTNQEIKRLLARVEEECKQLQRNQQQKQQAPLPAPPNDSDNDEEAPASSLKDHFPIEEAEEEDTSSQEESISPTPRSQPPPSVPSPYIRNLQEGLQSKGRPASPQSWAGISKSLRETVAQPGLVMQPTKQAQIVKTNQHLGSGQSSMRNSNTKVQVSSQNPPPSPMPGRVSAAPAVSRNQHLEGTGPFSTGTGCGHFGDRLGPSQSLQLQRGESGTAYPLPSKVKAAERLLAHASVAVDMALPSQGGPVSCSDVRHPASLSSSGSSGSPSSSVKMSSSTSSLTSSSSVSDGFKAQGPDCRIRDRG--TTQVQGGTAEHRPRNTPFMGIMDKIARFQQQVNPPSRSWHCPVTEGLLTNTATAAGLQ-TNSEKP-ALKPGGYCSQAKPCSVPPLGMGVHNG-AQVKELEENKCQVPALCQDNRKTKGVPHLYPEGVSKQPLHVSTEAHRSHLTSAKPKRSFIESNV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0VGY8-1", "uniprot_id": "TANC1_MOUSE", "id": "Q0VGY8-1", "name": "Protein TANC1", "aln": "-------------------------------------------------------------------------MLKAVLKKSREGGKGSKKEAGGDFGSETP---ALSSSGDSPVNSLSTTEDTYRVSLAKGVSMSLPSSPLLPRQSLLTQSRSNKKSPGPVRKPKYVESPRVPGDPVMIPFGEGSKPSEPSATEAKADNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEDKNEAMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAASKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGS-SLEWNRDGSLR--------LGVQKGVLHDRRADNCSPVAEEET--TGSAESVLPKAEPSAGDGPVPYP-QSSGSLIMPRPN------------------------------------------------------SVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGG-RAPEVKARFAPYKPQEILLKPLLFEVP-------------------------------------------------SITTDSVFVG------------------------------------RDWLFHQIEENLRNTELAENR--GAVVVGSVGFG------------------------------------------------KTAIISKLVALSCHGSRMRQIASSSPSLSPKSSDPTQDLPGTPLLSPSSSTSALSVT--------------------------------------------------------------------------------------------------------------------------------------------------------------------RTPAGPGTADSQRPREDAVKYLASKVVAYHYCQADNTYTCLVPEFVHSIAALLCRSHQLAAYRDLLIKEPQLQSMLSLRSCVQDPVAAFKRGVLEPLTSLRNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIIPKFPTWLKLIVTVRANFQEIISALPFVKLSLDDFPDNKDIHSDLHAYVQHRVHSSQDILSNIS----LNGKADAALISKVSSHLVLRSLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFDRALPILNVALASLHPMTDEQIFQAINAGHI-QGEQGWEDFQQRMEALSCFLIKRRDKTRMFCHPSFREWLVWRADGESTAFLCEPRNGHALLAFMFSRQESKLNRQQTMELGHHILKAHIFKGLSKKTGVSSSHLQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGMSENGMNALCYAAAAGHMKLVCLLIKKGARVDHLDKKGQCALVHSALRGHSDILQYLLNCEWSAGPPQPGTLRKSQALQQALTAAASMGHSSVVQSLLGMAE-EHEIEVNGTDTLWGETALTAAAGRGKVEICELLLERGAAVSRANRRGVPPLFCAARQGHWQVVRLLLDRGCDVNLSD-KQGRTPLMVASCEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAEIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTAVVVTLLRKGAKLGNAAWAMATSKPDILIILLQKLVEEGNVMYKKGKMKEAAQRYQYALRKFP-REGLGEDMRPFNELRVSLYLNLSRCRRKTNDFGLAEEFASKALELKPKSYEAFYARARAKRNSRQFLAALADLQEAVKLCPNNQEIKRLLARVEEECKQLQRNQQQKQQGPPPAPANDSDNEEDAPASSLKDHFPIEEAEEEDTSSQEESISPTPRSQPPPSVPSPYIRNLQEGLQSKGRSASPQSRAGISKSLRETVAQSGLVMQPTKQAQIVKTNQHLGSGQSSMRNSSTKIQVSSQNPPPSPMPGRVSAAPAVSRNQHLEGTGPFTAGTGCGHFGDRLGASQSLQLQRSESGTAYPLPSKVKAAERLLAHASVAVDMAPPNQGGPVSCSDVRHPASLSSSGSSGSPSSSIKMSSSTSSLTSSSSVSDGFKVQGPDSRIRDKG--TTQVQGGTAEHRPRNTPFMGIMDKTARFQQQSNPPNRSWHCPVAEGLLTNTATAAGLQ-SNSEKP-TLKPGGYCSQAKPCSVPPLSMGVHNG-AQVKELEENKCQIPALCQDNRITKGVPHLYPEGVSKQPLHVSTEAHRSHLTSAKPKRSFIESNV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0D5-1", "uniprot_id": "TANC1_HUMAN", "id": "Q9C0D5-1", "name": "Protein TANC1", "aln": "-------------------------------------------------------------------------MLKAVLKKSREGGKGGKKEAGSDFGPETSPVLHLDHSADSPVSSLPTAEDTYRVSLAKGVSMSLPSSPLLPRQSHLVQSRVNKKSPGPVRKPKYVESPRVPGDAVIMPFREVAKPTEPDEHEAKADNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEDKNETMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAANKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGS-SLEWNKDGNLR--------LGVQKGVLHDRRADNCSPVAEEET--TGSAESTLPKAESSAGDGPVPYS-QGSSSLIMPRPN------------------------------------------------------SVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGG-RAQEVKARFAPYKPQDILLKPLLFEVP-------------------------------------------------SITTDSVFVG------------------------------------RDWLFHQIEENLRNTELAENR--GAVVVGNVGFG------------------------------------------------KTAIISKLVALSCHGSRMRQIASNSPGSSPKTSDPTQDLHFTPLLSPSSSTSASSTA--------------------------------------------------------------------------------------------------------------------------------------------------------------------KTPLGSISAENQRPREDAVKYLASKVVAYHYCQADNTYTCLVPEFVHSIAALLCRSHQLAAYRDLLIKEPQLQSMLSLRSCVQDPVAAFKRGVLEPLTNLRNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIISKFPAWLKLIVTVRANFQEIISALPFVKLSLDDFPDNKDIHSDLHAYVQHRVHSSQDILSNIS----LNGKADATLIGKVSSHLVLRSLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFERALPILNVALASLHPMTDEQIFQAINAGHI-QGEQGWEDFQQRMDALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTAFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKKTGISSSHLQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGTSENGMTALCYAAAAGHMKLVCLLTKKGVRVDHLDKKGQCALVHSALRGHGDILQYLLTCEWSPGPPQPGTLRKSHALQQALTAAASMGHSSVVQCLLGMEK-EHEVEVNGTDTLWGETALTAAAGRGKLEVCELLLGHGAAVSRTNRRGVPPLFCAARQGHWQIVRLLLERGCDVNLSD-KQGRTPLMVAACEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAAIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTSVVVALLRKGAKLGNAAWAMATSKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYALRKFP-REGFGEDMRPFNELRVSLYLNLSRCRRKTNDFGMAEEFASKALELKPKSYEAFYARARAKRNSRQFVAALADLQEAVKLCPTNQEVKRLLARVEEECKQLQRSQQQKQQGPLPAPLNDSENEEDTPTPGLSDHFHSEETEEEETSPQEESVSPTPRSQPSSSVPSSYIRNLQEGLQSKGRPVSPQSRAGIGKSLREPVAQPGLLLQPSKQAQIVKTSQHLGSGQSAVRNGSMKVQISSQNPPPSPMPGRIAATPAGSRTQHLEGTGTFTTRAGCGHFGDRLGPSQNVRLQCGENGPAHPLPSKTKTTERLLSHSSVAVDAAPPNQGGLATCSDVRHPASLTSSGSSGSPSSSIKMSSSTSSLTSSSSFSDGFKVQGPDTRIKDKV--VTHVQSGTAEHRPRNTPFMGIMDKTARFQQQSNPPSRSWHCPAPEGLLTNTSSAAGLQSANTEKPSLMQVGGYNNQAKTCSVSTLSASVHNG-AQVKELEESKCQIPVHSQENRITKTVSHLYQESISKQQPHISNEAHRSHLTAAKPKRSFIESNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TVH4-1", "uniprot_id": "A0AB32TVH4_DANRE", "id": "A0AB32TVH4-1", "name": "", "aln": "----------MTSEGGGGAARASSSAHRLSVREKRRPQTFPRRRINDINQSSHSWSH---------------AMFKAVLKKSRDGGK-NKKDAGEPLVLSGQ----WRCAGGGMPDPYPSADEGLRLGFSKGVSMSLPSSPLLPRHTYVMAARPCKKSPGLVRKPKYVESPRIPGDVCAASLKKVPDSATAG-----------SSSSTQELMTRLGFLLGEGIPGSTHIPMDGKNDKKCPVN-QGISPCSTLTSSTASPSTDSPCSTLNS----SGRPGLTAVCITSPSSTLDSKDSGIIATITSSSENEERSGS-SLEWSKEGSIRS-------CGQHVLGQTATRTDTCSPVAEEEPSASGTGLRIVPNTKKNS-EGPVQYTTQNPSSLMMPRPN------------------------------------------------------SVAATSSTKLEDLSFLDEQRNTPLRTSIRLPWHNTGG--RAPHDKACFAPYKPTDIMLKPLLFEVP-------------------------------------------------SITTDSVFVG------------------------------------RDWLFQQLEDDLSPSQSGESSSSGSILVGNVGFG------------------------------------------------KTAIISRLVALSCHGGRMRQIASNSPTASPKSAEVSSDVPLSQSTPPLSTSSTLSSS--------------------------------------------------------------------------------------------------------------------------------------------------------------------SCPN---TPELQRHRDQAVRRLAAKVVAYHYCQADNTYTCLVPEFVHSVSALLCRAHQLTAYRDLLLKETHLQSVLSLRSCVQDPSAAFRRGILQPLINLRKERKIPEEDCIILVDGLNEAEFHKPDYGDTVASFITKIIPKFPSWLKLIVTVRTNLLEITSLMPFSKISLDDFPDNQEIGTDLNAYIQQRISGSSNILSNIS----LNGKSDPVIVSKVSSHLISRSQGSYLYLKLTLDLFERGHLVIKSASYKVVPVSLSELYLLQCNMKFLSNSAFERAVPVLNVALASLHPLTDEQLFQALNAGSQ-RGELEWDDFQQRMETLSCFLIRRRDKTRMFCHPSFREWLVWRADGESSDFLCDPRSGHALMAFMLSRQEGKLNRQQTMELGHHILKAHIFKGLSKKTGVSSSVLQALWISCSTDGLSAALASLRNLYTPNVKVSRLLMLGGANVNYRTEVLNNGPVLCVQSHLGHQEMVALLLEFGANVDVLSENGMSALCYAAAAGHLELISLLCKRGAKVDHVDKSGQCALVHAALRGHSEVIECLLELHWSSESQQEHSLK-SRALQQALIAACSMGHIHVLEGLLAMND-ELSVQIDAHDTLWGETALTAAAGRGKMEVCSFLLKREAQVQQVNRRGACALFCAVRQGHWQIADLLLQHGADVNVSD-KQGRTLLMVAACEGHLSTADFLLSKGASVASVDKEGLTPLSWACLKGHKSVVQFLVEKGAVIDHSDKNGRSPLDLAAFYGDADIVHYLVEKGAVIEHVDYSGMRPLDRAIGCRNTSVVLTLLKKGAKLGNAAWAMATSKPDILIILLQKLMEEGNLLYKRGKMKEAAQRYQYALRKFP-REGFGDELKAFKELRVSLYLNLSRCRRKTNDFGLAEDFATKALELKPKSYEAYYARARAKRSSRQFTAALADLHEASKLCPNNREICRLLARVEDECKQMQRSQSKQQNLSNPE------------------HHQQEHAEEEEDDDDED----------DSEAWSQNIYSLNR--TSNGRSASPPHKHSLRQQHKS------LLLQPSKQAQIVKTNQHLGSLQPASGRG------KNQYAPSSPIPSRHISS----------------------------------VLKAGPGIDISPLAPANAVETEDLHHVQVHSTLDGANVN---ASQDLRKDANAS-----------MRVSSSTSSLASSSSLSDSGKTQGPDVRTKTRTDKGKISQSGSVDYKPR--PFMGVMDKTARFQQPT--ATRSWQSHSTDGVVASAG----------EITFAKPSSVYYEQMKG------PAGLHNGGLHAKEFG---------------HKEGKAVLAHSFTDSKPGLNRETATAHVASMKPKRSFIESNV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VTS9-1", "uniprot_id": "Q9VTS9_DROME", "id": "Q9VTS9-1", "name": "", "aln": "MPSLQQIALAMEGDQSELQTPPLPINPPPKVMANGIVYGFRTRHLSCIEENDSDSLHGSSIPHAYDMMQQADETFQKLNANEEQDESGSEDGGLENLDDTIAMIDESRLLEADYLDELVAEEQLQEQDEDEEESSDLVDSGNVEEDFWQPSFNRNDIMMTSVYGALNGSLTSEVSSTAAPGYSECATPRKEAEPVYATPEKRRASNRSFDSTCASLTSSLYGGSMNSSLDLKYSSLGGGDSVSGGISGTSTLRGTSVPPMDLSMISSDGVSALDWGSASVSCVLDSGDGNPAEELNEEMAAKCLSAAESDLQSIRRLLEHDASGSVCPSCRISFDKGKRRKLIDTCGHERCYSCMFRNDQCPMCMNSSLKDVDGANAQGYDTGIGGSTSTIVSPLGSPQPQLRSHAQRNAALARYMQQHRQESQSPDYHHRYASNGKLPRAAALSTNGNGFTTGTTQTVTVDVHHQLGGGGGGAAAAAKQLMANGISGHSRSSSMSHNIHAAAYSELSAAPPAFATPPTRRRFFNHKNLRSALTGGSGGGSGVGGGVGGAGGVGGGHRRTASNGGCPIDTASILSGDHTHQHHHRDNQPEGKESNALNTSTCSDSAVTRRRRKNVSNHNLKTSARHGASSENRLNRLSLAGTSVYAGHLSSLVFGKIKSLWSVNSSNSSEAGLNQLAGSDAIDHHSSFLNEKLQKDQLHARLGLLLNDPGSNGNSSSSGSGCEPISAHSTTSTTSSSGVGAASTTTSGSSQNVSPEQTLASGAGMLSGSQLSVATSHGVKEDALSLCGKFKAGCSMLHVYEALPSKSRKGNVRRSTRGQQGSSSSASAASAVGSRVTASSLAAVQLALKPLFFEVPLQEPDPPYVGRQWLVQQLSNILLGTETRVVLINGQPGTGKTAFCLQLVEYSCFGRRQMQDDPDGIYSQLQLGAHCERMRGLASHMVGYHFCQADANLTCQVPDFVHSLAAQLCQAPQLTAYRDYLLSEPHLQDILSVRECIADAERVMKLAILEPLAHLHRAGKIPAKVAVIVVDALCEAEYHRPDHGHTIASFLAQLTPHFPAWLKLVATVRTQMLELVKAPSYTQLTLDSWASSQALQQDMLDYIGARLADSPEIRMNIGGGGGQNSQSGSQPQTKFVSHLQSLSRGSMLYAKLILDLIARGQLVIKSSSYKVLPVSLAQIFLLHFNLRFPTARSFEQAAPILNICLAALYPLTLDEIYYSMEALSHGREALSWPDFMQRFKLLDGFLIKRLDNTYMFFHSSLREWLMRRDEGESNKFLCDARLGHAGIAFRLSRLQAPLSPQLTLELGHHMLKAHLYGGTS-LTLLSPRDLQSYWLAGAADNISSSLGALRNVYSPNLKVSRLVLLAGASPNHRTDYMGGAPILCIAAHEGILPMVSLLLEFGADVGLTNSQGCTPLILAAMRGHCDVVRPLVAAGSSLGQLDITQRCALVHAARMGHLSVVKYLLACDWSPRP-HSQDVTRSVALQQALIGAAAQAHCKILEDLLDLNETEFDLDVNGMEPSSGELALTAAARHGCIDVVGILLSRGAQIDARNRQGYSALWLAVKEGHWSVVEHLLQRGALLDEPLGQTRKTPLMIAAEEGHLELVDLLLARGAQREAQDHEGFTALSWACLRGHLAAAKTLIEHGCNRHHEDHNGRTALDLAAYQGAASLVIYILEQGGNLEHIDVHGMRPLDRAIACRNIQAVQVFLRKGAKLGPTTWSMAMGKPEILVILLNKLLEDGNVLYRKNRFQEAAHRYQYALRKISGLEQLLERNAIFAQLRTNLLLNLSRCKRKLNELDASIDLATQAIAQKPHSYEGYYARAKARMELGALNEALVDANEAMQQAAQSG----VLCEVVEVLKRIQTELLTR----------------------------ISISSEDQTGRMSN--------------------------IGGGASVAYESHHEITDL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : :..:. . .:. . : . . : :: . . : * .* .* : .. . . * . . . .. : . . .* : : * . : : :. .. *** *** .::..* * *: . . .. :. ... :. :. : *. *::*.: :* ** . .*.: * : : * . .: . : ... :* ...::: * . :..:*.:..:: *. . . :: :* :. .* : . :: * * .* .* * *:: * :: :::: . .*. :.*. :. * : ::* * . . : :*... . ::. : . : . *:::: * * : : : :: **:::*.**:**** . ** **:****::: **:: **:**** *: *.:**.:*.:*.*: *. .:: .:*:** *:. *** : :*::*.* ***:*:**:*.*::**:::: .:**.****:.***::: *: . .: :::**.:...: : *: *: *: .* :* **. *.::.. *. *:* . ** ** ** ***: **:*****:****:****::::**: *::* : :*::* *:**:.**:*:*:* :::: :::* : * ** *::. *. ***:: *:* ** *.*:****: * :**.. ***:.* *** :** :** :. *. * *:*****:****:: * * * :*. *: *:. :::.:*::*.:***:*:**:*****::*.**. *:**: :...*:**: :* * :*:******* :. ..:* ..* ** ** .:: * * :.::* . :*****:* ** .::: ** .**. . : : * ****** .*.: .* ::: ** : . * .::::. :. ** ****** :* ::: :** : * :. **:* .*: *.::***.:. **::*. :: : :* **:*: ****. .::**::** : *:**::.******:** :..: *:*.*. .: *:***:.*****: * *. * *::*:*. :**:* *********.*** .* .:*:****** ::*:** **:**:***:**:*:**::*::.:::***:********:. * : * :**..* ******:** *::. : ::*::*: **:***.:****:*: . : **.* :** : .. . :*..* : *::* . : . :.*:: . .: . * ..: : . ", "identical_positions": 427, "similar_positions": 504, "identity": "18.48%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-957", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TDX6-1", "uniprot_id": "CGAT1_HUMAN", "id": "Q8TDX6-1", "name": "Chondroitin sulfate N-acetylgalactosaminyltransferase 1", "aln": "MMMVRRGLLAWISRVVVLLVLLCCAISVLYMLACTPKGDEEQLALPRANSPTGKEGYQAVLQEWEEQHRNYVSSLKRQIAQLKEELQERSEQLRNGQYQASDAAGLGLDRSPPEKTQADLLAFLHSQVDKAEVNAGVKLATEYAAVPFDSFTLQKVYQLETGLTRHPEEKPVRKDKRDELVEAIESALETLNSPAE-NSPNHRPYTASDFIEGIYRTERDKGTLYELTFKGDHKHEFKRLILFRPFGPIMKVKNEKLNMANTLINVIVPLAKRVDKFRQFMQNFREMCIEQDGRVHLTVVYFGKEEINEVKGILENTSKAANFRNFTFIQLNGEFSRGKGLDVGARFWKGSNVLLFFCDVDIYFTSEFLNTCRLNTQPGKKVFYPVLFSQYNPGIIYGHHDAVPPLEQQLVIKKETGFWRDFGFGMTCQYRSDFINIGGF-DLDIKGWGGEDVHLYRKYLHSNLIVVRTPVRGLFHLWHEKRCMDELTPEQYKMCMQSKAMNEASHGQLGMLVFRHEIEAHLRKQKQKTSSKKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BJQ9-1", "uniprot_id": "CGAT1_MOUSE", "id": "Q8BJQ9-1", "name": "Chondroitin sulfate N-acetylgalactosaminyltransferase 1", "aln": "--MVRRGLLGWISRVVILLVLLCCAISVLYMLACTPKGDQEQLGLPRANGPTGKDGYQAVLQEREEQHRNYVNSLKRQIAQLKDELQARSEQFRSGQDQASDATSLRSGWDREPKAQADLLAFLRGQVDKAEVHAGVKLATEYAAVPFDSFTLQKVYQLETGLTRHPEEKPVRKDKRDELVEAIESALESLNSPVE-SSPHQRPYTAADFIEGIYRTERDKGTLYELTFKGDHKHEFQRLVLFRPFGPIMKVKKEKLNLANTLINVIVPLARRVDKFRHFMQNFREMCIQQDGRVHLTVVYFGKEEMNEVKGILENTSKAANFRNFTFIQLNGEFSRGKGLDVGARFWKGSNVLLFFCDVDIYFTSEFLNTCRLNTQPGKKVFYPVLFSQYNPGVIYGHHDAVPPLGQQLVIKKETGFWRDFGFGMTCQYRSDFINIGGF-DLDIKGWGGEDVHLYRKYLHSNLIVVRTPVRGLFHLWHEKHCMDELTPEQYKMCMQSKAMNEASHGQLGMLVFRHEIEAHLRKQKQKASSKKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B6M3-1", "uniprot_id": "A0ACD6B6M3_DANRE", "id": "A0ACD6B6M3-1", "name": "Hexosyltransferase", "aln": "---MRCSLR------CVFWALLFLCVLLLYRQSCR---IHMQSGIPKDG-----DLEQDMLELQDQHFLQLSTNLSRLIQELRGELR-RS------------AFALPED-------QQELQDFLHQQILRAESRSADRLEDEFMVLPFQSFSLRSVCQLETGLSRRPEEAELRPDRRNELNEALEAALHLLNQPEPGDSQTRRIYSPKHFSEGIFRTERDTGTIYDLAFREDNVPDFRRLVFFRPFAPLVKVREDLLDASQLLINIIVPLTNTVDTFRRFMQQFSEVCIGQDGLTHLTVVFFGSEKMEEVKGILDVISRRMKYRNMTLIHLNEDFSRSRALDVGARAWKHDNVLLFFCDVNVHFTAEFLNSCRINAQPGQKVFYPVMFSLYNPELLYGQH--VPPAQQQMVVRKDYGFWKDDDFSTACLYRSDFMNAGGFGAFSARGSDTADLHLYRKLLHSGMMVVRAPSRGLFLMWHQTVCS---STEAFQQCVQNKALNEASHAQLGLRVFQKQIQEHLSRRQHMQT----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .* :: .** .: :** :* . * .:*: . : * :*: :::. : ..*.* * :*: **: ** * .* . * :* **: *: :** .:. :* *: .:**:**:*:.* ******:*:*** :* *:*:** **:*:**. **.* .* :* *:. .* ***:*****.**:*:*:*: *: :*:**::****.*::**::: *: :: ***:****:. **.**:***:* *:** *** .*****:**.*:::******: *: ::**:*:*:** :***.:.****** ** .*********:::**:****:**:*:***:******:** *** ::**:* *** **:*::*: ***:* .*. :* *****:* *** :. :* . *:***** ***.::***:* **** :**:. * :.* :: *:*.**:*****.***: **:::*: ** :::: : ", "identical_positions": 237, "similar_positions": 155, "identity": "44.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-958", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7F172-1", "uniprot_id": "F7F172_RAT", "id": "F7F172-1", "name": "12S rRNA N(4)-cytidine methyltransferase METTL15", "aln": "----------------MLR---------------------YPYFCRTYN-----RLFSYFVDSGAFN-LDVCPH--TIHTTAAMHTEYKASEGIALCDTQKVYRSEETDSEAMAK--LHIPVMVDEVVQCLTPQKGQVFLDMTFGSGGHSKAILQKEPDVTVYALDRDPVAFTLAERLS--EMYPTQIHAMLGQFSQAETLLMKAGVQPGTVDGVLLDLGCSSMQLDAPERGFSLRKDGPLDMRMDGDRYPDMPTAADVVNALDQQALASILRAYGEEKHAKKIASAIIQAR-STYPISRTQQLASIVAGAFPPSAIYARKDLLQRSTHIATKTFQALRIFVNNELNELYTGLRTAQKFLKPGGRLVALSFHSLEDRIVKRFLLGISMTERFNLSIRQKVRQTSQMDSDHE-IEERRCVRAPLKWELIHKKVLTPEDQDVQANPRGRSAKLRAAIKL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCL4-1", "uniprot_id": "MET15_MOUSE", "id": "Q9DCL4-1", "name": "12S rRNA N(4)-cytidine methyltransferase METTL15", "aln": "----------------MLR---------------------YPYFYRTYN-----RLFSHFVDSGASN-LDVCPH--TIHTAVALHTESKAVEGTALCGPQKVYSSEEKELEAMAK--LHIPVMVDQVVHCLAPQKGQVFLDMTFGSGGHTRAILQKEPDVMVYALDRDPVAYAIAEQLS--RLYPTQIQALLGQFSQAEALLMKAGVQPGTIDGILMDLGCSSMQLDAPERGFSLRKDGPLDMRMDGDRYPDTPTASDVVNALDQQALASILRAYGEEKHAKKIASAIIQAR-STYPISRTQQLASIVAGAFPPSAVYARKDLLQRSTHIATKTFQALRIFVNNELNELYAGLRTAEKFLKTGGRLVALSFHSLEDRIVKRFLLGISMTERFNLSIRQKVKQTSQLDSDQE-TEERHSVRAPLKWELIHKKVLTPEDQDVQDNPRGRSAKLRAAIKL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NJ78-1", "uniprot_id": "MET15_HUMAN", "id": "A6NJ78-1", "name": "12S rRNA N(4)-cytidine methyltransferase METTL15", "aln": "----------------MLR---------------------YPYFCRMYK-----ECLSCWLESGIPN-LGVWPN--RIHTTAEKYREYEAREQTDQTQAQELHRSQDRDFETMAK--LHIPVMVDEVVHCLSPQKGQIFLDMTFGSGGHTKAILQKESDIVLYALDRDPTAYALAEHLS--ELYPKQIRAMLGQFSQAEALLMKAGVQPGTFDGVLMDLGCSSMQLDTPERGFSLRKDGPLDMRMDGGRYPDMPTAADVVNALDQQALASILRTYGEEKHAKKIASAIVQAR-SIYPITRTQQLASIVAGAFPPSAIYTRKDLLQRSTHIATKTFQALRIFVNNELNELYTGLKTAQKFLRPGGRLVALSFHSLEDRIVKRFLLGISMTERFNLSVRQQVMKTSQLGSDHENTEEVSMRRAPLMWELIHKKVLSPQDQDVQDNPRGRSAKLRAAIKL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0C7V9-1", "uniprot_id": "ME15P_HUMAN", "id": "P0C7V9-1", "name": "Putative methyltransferase-like protein 15P1", "aln": "----------------MLR---------------------YPYFCRMYK-----ECLSCWLESGIPN-LGVWPK--RIHTTAEKYREYEAREQTDQTQVQELHRSQDRDFETMAK--LHIPVMVDEVVHCLSPQKGQIFLDMTFGSGGHTKAILQKESDIVLYALDRDPTAYALAEHLS--ELYPKQIRAMLGQFSQAEALLMKAGVQPGTFDGVLMDLGCSSMQLDTPERGSSLRKDGPLDIRMDGGRN-----------------ISSLCYLYTER-----LTTAIY---------------------------LYCHQDFPG-SSHICEQ-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58FZ98-1", "uniprot_id": "A0AC58FZ98_DANRE", "id": "A0AC58FZ98-1", "name": "12S rRNA N(4)-cytidine methyltransferase METTL15", "aln": "MTYDAATEWTESIESRMMKNLIYGGYMGWNKARNVSYIEHYDFYAIRYSRIYMPQYYSCFMAAPCRQTLGVWKHVATLRNPRMFRRCWRKSWHPGRLYTGSVPSSPDCEMPVQEEKPFHTPVMVKEVLQFLNIKPGQIVLDLTFGAGGHSKAILQSVPGVTVVAADRDPTAFRMAQQLA--EEYQGKVKPVLGRFSELNNLLPALGLGPGTVDAALLDAGCSSMQMDSAERGFSLSKDGPLDMRMDGDRYPDMPCAADVVNALDQQALASVLAAYGEERHTRKIAAAIAQAR-SVYPIGRTLQLASIVAGAFPASALYARRDRLQRPSHVATKTFQALRIFVNDELNELHAGLRVAQTLLRPKGRLCVLTFHSLEDRLTKRFLRGEDLAAPPRRSLRQHARARPAGQEEEFEEEEEGDEGGNSVHWVSLKKVIKPSEEEVQENPRARSAKLRTAVRQ-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGY5-1", "uniprot_id": "MET15_DROME", "id": "Q9VGY5-1", "name": "Probable methyltransferase-like protein 15 homolog", "aln": "----------------MKR----------------------------------------------------------LLNPTRLRLDWLRRSSIDVTTAP------------------HVPVLCDTAIEYLQPVPGGTYFDMTFGAGGHTRRLLEKCPEAKVYALDRDPLAHQLARDMSESEEFKGRLIPLLGKFSDLPKLFKEHGLAKNSVDGMLFDFGCSSMQFDEAVRGFSISRDGPLDMRMDGGHSGG-VTAADVLANVEEGDLVKILRMYGEEKAAKKIARGLVDARNALFKIETTKQLADIIENIMDGG---TRKDKLRRPAHSATKTFQAIRIFVNNELNEINYGMVLANEILRVDGRLVTITFHSLEDTIVKRHINGNVLAGAAN---ALPLKYSSHYAIDEPDILESLTKKS---WKQLHRHVIVPDADEVARNTRSRSAKLRAAVKTN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : .. * **: . .:. * * :*:***:***:: :*:. . : * **** *. :*. :: . : :: .:**:**: *: *: .:.*. *:* ******:* . ** *: :*****:****.: : .: * *. :: .: ::* .:* . : ", "identical_positions": 53, "similar_positions": 60, "identity": "11.57%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-972", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6H9L7-1", "uniprot_id": "ISM2_HUMAN", "id": "Q6H9L7-1", "name": "Isthmin-2", "aln": "MRALRDRAGLLLCVLLLAALLEAALGLPVKKPRLRGPRPGSLTRLAEVSASPDPRPLKEEEEAPLLPRTHLQAEPHQHGCWTVTEPAAMTPGNATPPRTPEVTPLRLELQKLPGLANTTLSTPNPDTQASASPDPRPLREEEEARLLPRTHLQAELHQHGCWTVTEPAALTPGNATPPRTQEVTPLLLELQKLPELVHATLSTPNPDNQVTIKVVEDPQAEVSIDLLAEPSNPPPQDTLSWLP---ALWSFLWGDYKGEE-----KDRAPGEKGEEKEEDEDYPSEDIEGEDQEDKEEDEEEQALWFNGTTDNWDQGWLAPGDWVFKDSVSYDYEPQKEWSPWSPCSGNCSTGKQQRTRPCGYGCTATETRTCDLPSCPGTEDKDTLGLPSEEWKLLARNATDMHDQDVDSCEKWLNCKSDFLIKYLSQMLRDLPSCPCAYPLEAMDSP-VSLQDEHQGRSFRWRDASGPRERLDIYQPTARFCLRSMLSGESSTLAAQHCCYDEDSRLLTRGKGAGMPNLISTDFSPKLHFKFDTTPWILCKGDWSRLHAVLPPNNGRACTDNPLEEEYLAQLQEAKEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3Z6A3-1", "uniprot_id": "D3Z6A3_MOUSE", "id": "D3Z6A3-1", "name": "", "aln": "MRPPPSRARFPRALMLLAALLATGRGLPLRK---RGPGPHGHSRMAEASPAPDLSSPKEKNTTPGFPGDHLQTEPCQPGCQTIPEPAALTLGTATSPRTLEHTPLLLELQKLPGLANTDLSAPNP---------------------------------------------------------------------------------NIQVTIEVVQDPQTEVEMDLPSEPSNLWPLHAPSWLPTKEFFWPLFWGYQEGEEGATSLRDRAPGEA--EVEGGKDYAVEYGEGEDQRGTEEGEAEEP-WSSGAIDNWDYGWLGPQEQDFQQPDSYDCEPQEEWSTWSPCNGSCGSGYQQRTRPCGYACTATESRVCDLAPCPGTAEENTLGFPSEGWQPLAHNATDMLDPDVDSCEKWLNCKSDFLANYLSQVLKDLPSCPCAYPLEAVYSAAVSLQDEHQGRSFQWRDASSPQERLDIYQPTARYCLRSMLSSESSTLAAQHCCYDEGSRLLTRGKGAGAPDLVSTDFSPELHFKVDRLPWILCKGDWSRYHTVRPPNNGRACTDNPPEEEYLAQLQEAKEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F979-1", "uniprot_id": "E7F979_DANRE", "id": "E7F979-1", "name": "", "aln": "-MLIRSQALRWAVFLTLCALMVKGFPAKRRRANHIKSKSGASLEVRGHGGSKDVKQSLQDIQGQNQLRSELPLPRRHKRRWSRIHSEGVLP---KPAPEEEEETFILDLKNFPDLANADLGSQNP---------------------------------------------------------------------------------NIQVTIEVVDSPQMEIEMDLAKESRNDWSLSSEEWLGHKKLFWPLFWEYHDSSQ-------EGPGQG--SLEENEEDLIY--EGEDS------------FLSGVGADWNSRWKG-----WDSTDNYEYE-EEEWSDWSPCSATCGQGNQKRIRSCGYACTATESRTCDLERCP----DDIIPVTEPSPHEMANN-TELLGTDVDSCEKWLNCKNDFLQKYLHKVLTELPNCPCVYPSEVVYSA-VNVFDRKLQKTYRWRDASGPKERLDIYKPSARFCIRSMLSFDSTTLAAQHCCYDDHMKLITRGKGAGAPNLISTEFSPELHYKVDVLPWILCKGDWSRFHSVRPPNNGLQCVDNPQENVYMNELEEAREY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:* .: *.**: . :: . . . .: . : * :. .* : : .. .: ... * .: *:*:::*.***: *.: ** : ****:**:.** *:.:** *. * . : .** :*.::* ...: ..**: . * .:: ****. : .*. :*: * . :... .*: * ::*** ****...*. * *:* *.***.*****:*.*** ** .: : ... : :*.* *:: . ************.*** :** ::* :**.***.** *.: *. *.: *.: ::::*****.*:******:*:**:*:***** :*:**********: :*:******* *:*:**:***:**:*.* *********** *:* ***** *.*** *: *: :*:**:**", "identical_positions": 183, "similar_positions": 142, "identity": "31.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-997", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H930-4", "uniprot_id": "SP14L_HUMAN", "id": "Q9H930-4", "name": "Nuclear body protein SP140-like protein", "aln": "MAGGGSDLSTRGLNGGVSQVANEMNHLPAHSQSLQRLFTEDQDVDEGLVYDTVFKHFKRHKLEISNAIKKTFPFLEGLRDRELITNKMFEDSEDSCRNLVPVQRVVYNVLSELEKTFN---LSVLEALFSEVNMQEYPDLIHIYKSFKN-------------------------------------------------------------------------------------------------------------------------------------------------AIQDKLSFQES--------------------------------------------DRKEREER------------------------------PDIKLSLKQGE-------------------------------------------------------------------------------VPESPEARKESDQACGKMDTVDIANNSTLGK-----PKRKRRKKK-----GHGWSRMGTRTQKNNQQNDNSKADGQLVSSEKKANMNLKDLSKIRGRKRGKPGTHFTQSDRAPQK------RVRSRASRKHKDETVDFQAPLLPVTCGGVKGILHKEKLEQGTLAKCIQTEDGKWFTPMEFEIKGGYARSKNWRLSVRCGGWPLRRLMEEGSLPNPPRIYYRNKKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVESE--KTPWNCIFCRMK---ESPGSQQCCQESEVLERQMCPEEQLKCEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQDMRLIFQNHRASYKYKDFGQMGLRLEAEFEKDFKEVFAIQETNGNS----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q13342-1", "uniprot_id": "SP140_HUMAN", "id": "Q13342-1", "name": "Nuclear body protein SP140", "aln": "-------MAQQGQQGQMASGDSNLNFR----MVAEIQNVEGQNLQEQVCPEPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNLVPVTRVMYCVLSELEKTFG---WSHLEALFSRINLMAYPDLNEIYRSFQNVCYEHSPLQMNNVNDLEDRPRLLPYGKQENSNACHEMDDIAVPQEALSSSPRCEPGFSSESCEQLALPKAGGGDAEDAPSLLPGGGVSCKLAIQIDEGESEEMPKLLPYDTEVLESNGMIDAARTYSTAPGEKQGEEEGRNSPRKRNQDKEKYQESPEGRDKETFDLKTPQVTNEGEPEKGLCLLPGEGEEGSDDCSEMCDGEEPQEASSSLARCGSVSCLSAETFDLKTPQVTNEGEPEKELSLLPGEGEEGSDDCSEMCDGEERQEASSSLARRGSVSSELENHPMNEEGESEELASSLLYDNVPGAEQSAYENEKCSCVMCFSEEVPGSPEARTESDQACGTMDTVDIANNSTLGK-----PKRKRRKKR-----GHGWSRMRMRRQENSQQNDNSKADGQVVSSEKKANVNLKDLSKIRGRKRGKPGTRFTQSDRAAQK------RVRSRASRKHKDETVDFKAPLLPVTCGGVKGILHKKKLQQGILVKCIQTEDGKWFTPTEFEIKGGHARSKNWRLSVRCGGWPLRWLMENGFLPDPPRIRYRKKKRILKSQNNSSVDPCMRNLDECEVCRDGGELFCCDTCSRVFHEDCHIPPVEAE--RTPWNCIFCRMK---ESPGSQQCCQESEVLERQMCPEEQLKCEFLLLKVYCCSESSFFAKIPYYYYIREACQGLKEPMWLDKIKKRLNEHGYPQVEGFVQDMRLIFQNHRASYKYKDFGQMGFRLEAEFEKNFKEVFAIQETNGNN----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9HB58-1", "uniprot_id": "SP110_HUMAN", "id": "Q9HB58-1", "name": "Sp110 nuclear body protein", "aln": "-----------------------------------------MFTMTRAMEEALFQHFMHQKLGIAYAIHKPFPFFEGLLDNSIITKRMYMESLEACRNLIPVSRVVHNILTQLERTFN---LSLLVTLFSQINLREYPNLVTIYRSFKRVGASYEWQSRDTPILLEAPTGLAEGSSLHTPLALPPPQPPQPSCSPCAPRVSEPGTSSQQSDEILSESPSPSDPVLPLPALIQEGRSTSVTN---------------------------------------------DKLTSKMNAEEDSEEMPSLLTSTVQVASDNLIPQIRDKEDPQEMPHSPLGSMPEIRDNSPEPNDPEEPQEVSSTPS--------DKKGKKRKRCIWSTPKRRHKKKSLPGGTASSRHG-------------------------------------------------IQKKLKRVDQVPQKKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNEGKRSQKTPSTPRRVTQGAASPGHGIQEKLQVVDKVTQRKDDSTWNSEVMMRVQKARTKCARKSRLKEKKKEK--DICSSSKRRFQK------NIHRRG--KPKSDTVDFHCSKLPVTCGEAKGILYKKKMKHGSSVKCIRNEDGTWLTPNEFEVEGKGRNAKNWKRNIRCEGMTLGELLKR------------------------------KNSDECEVCCQGGQLLCCGTCPRVFHEDCHIPPVEAK--RMLWSCTFCRMK---RSSGSQQCHHVSKTLERQMQPQDQL--------------------------IRDYGEPFQEAMWLDLVKERLITEMY-TVAWFVRDMRLMFRNHKTFYKASDFGQVGLDLEAEFEKDLKDVLGFHEANDGGFWTLP-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6GKN6-1", "uniprot_id": "A0A8I6GKN6_RAT", "id": "A0A8I6GKN6-1", "name": "", "aln": "----------------------------MEGNSFSSRMSSEHENTETFPFELIFQHFKRQKVAISNAIKNPFPFLEGLRDHELITAKMYEDLQDSYRALVRVQEVIYRALDKLEKIFS---MKVLYEVFSNVNMEKYPDLQLIYQSFERVLPNGLCFQRSDGGDPNSQLSLEQGPNGSCSQATLTLSPFNHSFSDGWGSNDRLNSSLTHGNQSENHQLPGSPNHLVSSLEDGLSETVQTSRVRREA------------------TTSTTNNTNESARKCSTLLRSPGSVLEDACEFQVQLNNRDASPEPYSLQPSNEERAVQLNHDLQINPCSVRLVDIKKENISYSLDDNQQTQARTNENQ-------------------------GSEIIELSSDEDSNDEI-------------------------------------------------------------NLSEASTLILSKPETAHSRQPPTPRTYRRGDTSDTSSSSLDRR-------RKRTGHTIAVGNNPVLGRDGGRRRKKRERHGNYLIRNIKIPMNASWKTAFGTRHSNPSSQQGRKRERYQSGQREGPEPFENKVKRVPAGPRIHKDVNADFSSNELLVTCGKVVGTLYKEKLNQGIHVKSIQSTEGKWFTPLEFEIEGGYEKCKNWRQSIRCSGWPLKELIKRGELQDPPRKT--EMKETPPNSQQRKRKRKLKNLKACKVCGQRRRVRPCATCRKCYHKNCHIPPVEVQ--SGPWHCAFCKTRNQLRCQENQACHKESEVLKRKMSPEEQLKCELLLLTIYCCPKSGFFIRKPK--KRKEDFPDLQEHMWLNKIKHRLNKKAYHSVQHFVGDMRLIFQNHSKFYKSR-FKNLGVIVGNKFEKTFKSVFSIEDTSKQLQPSQHTVLLT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35892-1", "uniprot_id": "SP100_MOUSE", "id": "O35892-1", "name": "Nuclear autoantigen Sp-100", "aln": "----------------------------MEGSDGSPRMSTEQENTEMHLIECMLKHFKTQKVAISNAIRSTFPFLESLRDHEFITGKMYEDLLDSCRSLVPVDKVIYRALEELEKKFD---MTVLCELFNEVNMEKYPDLNLIRRSFGCVFPNELCFQGIDGGNPNSQLSLEQGPGASYSQGSPNGSSLDLSASEGWRSNDRRNSNLMQANQTENHQLAESPGHLDS------------------------------------------------------------------CELQVQLNNRDATPESCSLLPQNEERAVQLNYELQINPCFVQLVDVKKENSSFSLAGNQQTRARTNQNE-------------------------DSEIIELSSG-DSDNGE-------------------------------------------------------------NFSEATTTVPSQPAPAYSRKPPTLRRDRGGDTSDTESSIIIRR-------RKRTG------------------RKKRERLGSYLIRNIKIPMKPSWKTAFLARSANPSSQRRRKR-----------------------GPRIPREENADFGGAELPVVCGNAQGFLDKEKFKQGIYVRSIRGKTGRLFTPMDFEIEGNCEKAKNWRQSIRCKGWTLRELIQKGVLQDPPRK----KKETPRNP--RQTRRQVNAL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PDW0-1", "uniprot_id": "A0A8M9PDW0_DANRE", "id": "A0A8M9PDW0-1", "name": "", "aln": "--------------------------------------MEFNGQMDFLTDEQLLSVFHLKKTEIS-CIEQPLIFLTQLRDHNLLPETRFKKVKG-MRTREQRQQGVYDVLEWLERERSQDIRRFWRCVFEDHIVQKYPTLHLLRKSLPETVTKFSEERIGIETLTENSGQKEKNG-----------------------------------------------------------------------------------------------------------------------TYNRKRNDRSDDPGSSAKKPSFSPHEKGSKERIWMLSRYKTQLPVKCGDKEGILYRDKLAKGEKCIREG-------------------------AQGRWFSPSEFEKFAG-----------------------------------------------------------------------KESSRNWKASIRCDGTPLKKLIEENHLQCPPMK------NRDRTSVR---------------KSKKNISISSSESSSTDSETSASSEEESEAEDVQKQSKRAGLRSQFRSGVDDYGE------------EEDEMVDLTVFQAPSLPVSCVSLIGTLFKDRFATGRCGKSIR-TKQHWFTPEEFVKEEPTLSDGLWKRDILCHGKTLNFLCEKKILDIHPKN-----CTCVKCSTNPDDLMDQNNDDECNVCHSEGNLVCCDKCPRAFHPDCHLPAVNEEDSAWQWICTFCMLR--TRQRGCASRNMTEQEAFDVPISQCRLQCHYLLLCMYNEDIQKVFVKDPRP-NVRRYSEFISDPMWLNRIKQKLKDNMYQKFGEFASDFQLIFSNCRKFNRDNKFGQLGAKLKEIFEDEIQKIFFIQ----------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: * :* *: .* .: *: * *..::. : . * . :: * **: . :*. : ** * : :*: : . . . : . : . . : . : * : .. . . . :: . * * * * * * *.:: * :.*: :** :* : *: .: * * .* * :. . ", "identical_positions": 34, "similar_positions": 64, "identity": "3.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130530-999", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MA97-1", "uniprot_id": "F1MA97_RAT", "id": "F1MA97-1", "name": "Thrombospondin type-1 domain-containing protein 7A", "aln": "MGLRAGRLAS-------LSRGVLQLMR----LPLLLLLLLSSGARGAAAQGDTEVPTLYLWKTGPWGRCMGDDCGPGGIQTRAVWCAHSEGWTTLHTNCKQAVRPSNQQNCFKVCDWHKELYDWRLGPWNQCQPVISKSLEKARECVKGEEGIQVREITCIQKDKDIPAEDIICEYFEPKPLLEQACLIPCQQDCIVSEFSSWSECSRTCGSGLQHRTRHVVAPPQFGGSGCPNLTEFQVCQSNPCEAEESMYSLQVGPWSACS-------VPHSRQARQARRRGKNKEREKERGKAVKDPEARELIKKKRNRNRQNRQENRYWDIQIGYQTRDVMCLNRTGKSADLSFCQQERLPMTFQSCVITKECQVSEWSEWSPCSKTCHDVTSPTGTRVRTRTIRQFPIGSEKECPELEEKEPCLSQGDGAVLCATYGWRTTEWTECHVDPLLSQQDKRRANQTALCGGGVQTREIYCIQTNDILLSHINTQKDKE-----------------------ASKPVDSKLCTGPVPNTTQLCHVPCPIECEVSPWSAWGPCTYENCNDQQGKKGFKLRKRRITNEPTGGSGATGNCPHLLEAIPCEEPSCYDWKSVRLGDCEPDNGKACGPGTQVQEVVCINSDGEEVDRQLCRDAIFPIPVACDAPCPKDCVLSAWSTWSSCSHTCSGKTTEGKQIRARSILAY-AGEE------------------------GGIRCPNSSALQEVRSCNEHPCTVYHWQTGPWGQCIEDTSVSSFNTTTTWTGETSCSVGMQTRKVICVRVNVGQVGPKKCPESLRPETVRPCLLPCRKDCIMTPYSDWTPCPSSCREGDSGAR-KQSRQRVIIQLPAYGGRECSDPLYEEKACEAPPTCHSYRWKTHKWRRCQLVPWSIQQDVPGAQEGCGPGRQARAITCRKQDGGQASIQECLQYAGPVPALTQACQIPCQDDCQFTSWSKFSSCNGDCGAVRTRKRAIVGKSKKKEKCKNSHLYPLIETQYCPCDKYNAQPVGNWSDCILPEGKAEVLLGVKVQGDNKECGQGYRYQAMACYDQNGRLVETSRCNSHGYIEEACIIPCPSDCKLSEWSNWSRCSKSCGSGVKVRSKWLREKPYNGGRPCPKLDHVNQAQVYEVVPCHSDCNQYIWVTEPWSVCKVTFVDMRDNCGEGVQTRKVRCMQNTADGPSEHVEDYLCDPEDMPLGSRECKLPCPEDCVISEWGPWTQCSLPCNPSGSRQRSADPIRQPADEGRACPDAVEKEPCNLNKNCYRYDYNVTDWSTCQLSEKAVCGNGIKTRMLDCVRSDGKSVDLKYCEELGLEKNWQMNSSCTVECPLNCQLSDWSPWSECSQTCGLTGKMIRRRTVTQPFQGDGRPCPSLMEQSKPCPVKPCYRWQYGQWSPCQVQEAQCGEGTRTRNISCVVSDGSADDFSKAVDEEFCANIELIIDGNKQIVLEETCTQPCPGDCYLNDWSSWSLCQLTCVNGEDLGFGGIQVRSRAVIIQELENQHLCPEQILETKSCDDGQCYEYKWMASAWKGSSRTVWCQRSDGVNVTGGCLVVSQPDADRSCNPPCSQPHSYCSEMKACRCEEGYTEVMSSNSTLEQCTLIPVVVIPTVEDKR-DVKTSRAVHPTQPSSNPAGR-GRTWFLQPFGPDGRLKTWVYGVAAGAFVLLVFIVSMIYLACKKPKKPQRRQNN-RLKPLTLAYDGDADM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q69ZU6-1", "uniprot_id": "THS7A_MOUSE", "id": "Q69ZU6-1", "name": "Thrombospondin type-1 domain-containing protein 7A", "aln": "MGLRAGRLAS-------PSRGVLQLLR----LPLLLLLLLSSGARGAAAQGDTEVPTLYLWKTGPWGRCMGDDCGPGGIQTRAVWCAHVEGWTTLHTNCKQAVRPSNQQNCFKVCDWHKELYDWRLGTWDRCQPVISKSLEKSRECVKGEEGIQVREIMCIQKDKDIPAEDIICEYFEPKPLLEQACLIPCQKDCIVSEFSPWSECSRTCGSGLQHRTRHVVAPPQYGGSGCPNLTEFQVCQSNPCEEDESLYSLQVGPWSACS-------VPHTRQARQARRRGKNKEREKERGKAVKDPEARELIKKKRNRNRQNRQENRYWDIQIGYQTRDVTCLNRTGKSADLSFCQQERLPMTFQSCVITKECQVSEWLEWSPCSKTCHDVTSPTGTRVRTRTITQFPIGSEKECPALEEKEPCVSQGDGAVLCATYGWRTTEWTECHVDPLLSQQDKRRANQTALCGGGVQTREIYCIQTNDNMLSHGNTQKDKE-----------------------ASKPVDSKLCTGPVPNTTQLCHVPCPIECEVSPWSAWGPCTYENCNDQQGKKGFKLRKRRITNEPTGGSGATGNCPHLLEAIPCEEPSCYDWKSVRLGDCEPDNGKSCGPGTQVQEVVCINSDGEEVDRQLCRDAIFPIPVACDAPCPKDCVLSAWSSWSSCSHTCSGKTTEGKQTRARSILAY-AGEE------------------------GGIRCPNISALQEVRSCNEHPCTVYHWQTGPWGQCIEDTSVSSFNTTTTWNGEASCSVGMQTRKVICVRVNVGQVGPKKCPESLRPETVRPCLLPCRKDCVVTPYSDWTPCPSSCREGDSGAR-KQSRQRVIIQLPANGGKECSDPLYEEKACEAPPTCHSYRWKTHKWRRCQLVPWSIQQDVPGAQEGCGPGRQARAITCRKQDGGQASIQECLQYAGPVPALTQACQIPCQDDCQFTSWSKFSSCNGDCGAVRTRKRAIVGKSKKKEKCKNSHLYPLIETQYCPCDKYNAQPVGNWSDCILPEGKAEVLLGMKVQGDSKECGQGYRYQAMACYDQNGRLVETSRCNSHGYIEEACIIPCPSDCKLSEWSNWSRCSKSCGSGVKVRSKWLREKPYNGGRPCPKLDHVNQAQVYEVVPCHSDCNQYIWVTEPWSVCKVTFVDMRDNCGEGVQTRKVRCMQNTADGPSEHVEDYLCDPEDMPLGSRECKLPCPEDCVISEWGPWT-CALPCNPSGSRQRSADPIRQPADEGRACPDAVEKEPCSLNKNCYHYDYNVTDWSTCQLSEKAVCGNGIKTRMLDCVRSDGKSVDLKYCEELGLEKNWPMNTSCTVECPVNCQLSDWSSWSQCSQTCGLTGKMIRKRTVTQPFQGDGRPCPSLMEQSKPCPVKPCYRWQYGQWSPCQVQEAQCGEGTRTRNISCVVSDGSAEDFSKVVDEEFCANTELIIDGNKQIVLEETCTQPCPGDCYLNDWSSWSLCQLTCVNGEDLGFGGIQVRSRAVIIQELENQHLCPEQMLETKSCDDGQCYEYKWVASAWKGSSRTVWCQRSDGINVTGGCLVVSQPDTDRSCNPPCSQPHSYCSEMKTCRCEEGYTEVMSSNSTLEQCTLIPVVVIPTVEDKRGDVKTSRAVHPTQPSINPAGR-GRTWFLQPFGPDGRLKTWVYGVAAGAFVLLVFIVSMIYLACKKPKKPQRRQNN-RLKPLTLAYDGDADM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPZ6-1", "uniprot_id": "THS7A_HUMAN", "id": "Q9UPZ6-1", "name": "Thrombospondin type-1 domain-containing protein 7A", "aln": "MGLQARRWASGSRGAAGPRRGVLQLLPLPLPLPLLLLLLLRPGAGRAAAQGEAEAPTLYLWKTGPWGRCMGDECGPGGIQTRAVWCAHVEGWTTLHTNCKQAERPNNQQNCFKVCDWHKELYDWRLGPWNQCQPVISKSLEKPLECIKGEEGIQVREIACIQKDKDIPAEDIICEYFEPKPLLEQACLIPCQQDCIVSEFSAWSECSKTCGSGLQHRTRHVVAPPQFGGSGCPNLTEFQVCQSSPCEAEELRYSLHVGPWSTCS-------MPHSRQVRQARRRGKNKEREKDRSKGVKDPEARELIKKKRNRNRQNRQENKYWDIQIGYQTREVMCINKTGKAADLSFCQQEKLPMTFQSCVITKECQVSEWSEWSPCSKTCHDMVSPAGTRVRTRTIRQFPIGSEKECPEFEEKEPCLSQGDGVVPCATYGWRTTEWTECRVDPLLSQQDKRRGNQTALCGGGIQTREVYCVQANENLLSQLSTHKNKE-----------------------ASKPMDLKLCTGPIPNTTQLCHIPCPTECEVSPWSAWGPCTYENCNDQQGKKGFKLRKRRITNEPTGGSGVTGNCPHLLEAIPCEEPACYDWKAVRLGNCEPDNGKECGPGTQVQEVVCINSDGEEVDRQLCRDAIFPIPVACDAPCPKDCVLSTWSTWSSCSHTCSGKTTEGKQIRARSILAY-AGEE------------------------GGIRCPNSSALQEVRSCNEHPCTVYHWQTGPWGQCIEDTSVSSFNTTTTWNGEASCSVGMQTRKVICVRVNVGQVGPKKCPESLRPETVRPCLLPCKKDCIVTPYSDWTSCPSSCKEGDSSIR-KQSRHRVIIQLPANGGRDCTDPLYEEKACEAPQACQSYRWKTHKWRRCQLVPWSVQQDSPGAQEGCGPGRQARAITCRKQDGGQAGIHECLQYAGPVPALTQACQIPCQDDCQLTSWSKFSSCNGDCGAVRTRKRTLVGKSKKKEKCKNSHLYPLIETQYCPCDKYNAQPVGNWSDCILPEGKVEVLLGMKVQGDIKECGQGYRYQAMACYDQNGRLVETSRCNSHGYIEEACIIPCPSDCKLSEWSNWSRCSKSCGSGVKVRSKWLREKPYNGGRPCPKLDHVNQAQVYEVVPCHSDCNQYLWVTEPWSICKVTFVNMRENCGEGVQTRKVRCMQNTADGPSEHVEDYLCDPEEMPLGSRVCKLPCPEDCVISEWGPWTQCVLPCNQSSFRQRSADPIRQPADEGRSCPNAVEKEPCNLNKNCYHYDYNVTDWSTCQLSEKAVCGNGIKTRMLDCVRSDGKSVDLKYCEALGLEKNWQMNTSCMVECPVNCQLSDWSPWSECSQTCGLTGKMIRRRTVTQPFQGDGRPCPSLMDQSKPCPVKPCYRWQYGQWSPCQVQEAQCGEGTRTRNISCVVSDGSADDFSKVVDEEFCADIELIIDGNKNMVLEESCSQPCPGDCYLKDWSSWSLCQLTCVNGEDLGFGGIQVRSRPVIIQELENQHLCPEQMLETKSCYDGQCYEYKWMASAWKGSSRTVWCQRSDGINVTGGCLVMSQPDADRSCNPPCSQPHSYCSETKTCHCEEGYTEVMSSNSTLEQCTLIPVVVLPTMEDKRGDVKTSRAVHPTQPSSNPAGR-GRTWFLQPFGPDGRLKTWVYGVAAGAFVLLIFIVSMIYLACKKPKKPQRRQNN-RLKPLTLAYDGDADM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HF45-1", "uniprot_id": "A0AC58HF45_DANRE", "id": "A0AC58HF45-1", "name": "", "aln": "MGLGVRGART----------AFLCLWR---------LFYLLCGIWTACSQTTGDGKSLYFWETGPWGRCMGSECGPGGSQSRAVWCAHVEGWTTLHTNCLQSSRPANQQSCFRVCDWHKELYDWRRGAWNQCVPISLRTG-RTEACLQGEEGIQTREVYCSLRADGSTADDAICEYFEPKPRQEQACLIPCPKDCVVTEFTPWTTCSKTCGLGLQNRVRSVVAPPLFGGLPCPNLTEFQTCAPRACEGRETVFNLRVGGWSECQSLPVPPVVLPTSTAAPVRAVRQTRRRKGKERKGSRDPEMRELIKSKRNRNRLSRMEDDLWNMEIGFQARQVVCVHRNGSTVPLSQCPHWSLPELYQSCLMPRDCVLSEWSEWSSCSKACSDPKVPQGSRSRSRQLTRLPSGGGLECPQLEESEACEPEGDSVPPCALYTWRSTEWSECRVDALLSQQDRRRANHTGLCGGGVQTREVYCVQANAELLNYINNSKHKQEGQSSNGQMPSVPPLLSITYEISASPPVDVRLCKGATPSATQLCHIQCPVECQLSPWGAWGPCTFENCDERSVKKGFKFRRRSITNYPTGGE---GSCAHLVESIPCDDPSCFTWQLVKLEECIPEEDMDCGEGTQNPQVRCINNEGVEVEKEMCSDVVYPSPVPCVVPCPKDCALSLWTEWSTCSQTCSSKNAEGKQMRTRAILAYNAGEVTSMVVAWITVMEGLTRVPKFPELYGGSSCPNTSALQQVRNCNEHACVVYHWQTGPWSLCVEDGSSSSLNSSSSNADRASCTAGIQTRKVICVKVNVGQVPPKKCPEAPRPESVQVCQLPCKRDCIVTPYSEWTECPTSCDSGANGQKNKQSRYRVIIQRPANGGQECPDTLYEEKDCAAPSVCPGYRWKTHKWRKCQLVPWSIRRDSKGAQENCGAGIQTRAVSCRQLDGGLADVLQCLRSASSMPAVSQLCQLPCRDDCQLSGWSRFSPCSSDCVGVRTRRRNLLGKSKKKDKCKNSQMYPLSETQYCPCDKYNAQPVGNWSDCILPEG-------------MKECGQGYRYQAMVCYDQDNRLVETSRCNSHGYIEEACIVPCPSDCKLSEWSNWSRCSKSCGSGVKVRSKWLREKPYNGGRPCPKLDHLN--QVYEVVPCVSDCSQYVWVSEPWSVWKVSNVDLKENCGEGVQTRRVRCMMNTVDGPADAVEDYLCDPEEMPPGTRESRLPCPEDCVLSEWSRWTSCDLPCTGRGDRERTAFALRLPK-EGEDCPVSMQTEPCLLNRNCFHYSYNITDWSTCQLSANAVCGIGLKTRMLDCVRSDGKSVDLKYCKELRLEKKWQMNASCTVECPVNCQLSEWSAWSDCSQTCGLEGKMWRKRTVVQASQGDGRPCPFQMEQWKPCPVRPCYRWEYGQWSECRVEDVVCGVGVRFRNLSCFVSDGSSDGKSSIVEEELCAGLEKAVDGDKKIVLEETCTLPCPGDCYLMEWSDWGLCQSVCVKGQRLDFTPVQVRSRAVIAQEPENIAQCPDQEWQSRPCRNGECYDYQWMG-----GLQLVWCQRSDGINVTGGCPSALLPGADQSCDPLCDKPQSFCSEEAVCMCEEGFTEVLTTEGALEQCAPIPVLEIPTAGDKKADVKTSRAINPTLPTTVQPGRVGRTWYLQPFGADGKLKTWVYGVAAGVFVLLVFIVSMIYLACKKPKKPQRRQNNNRLKPLTLAYDGDVDM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** . : ..* * *: * * *.:* : :**:*:*********.:***** *:******* ********** *: ** ***.**:************ *.*::* *: :: :. *::******.**: * : .. .*:* ********* ******** :**:*:**:.*: **:*** ***:*.* ***** :** ********.* . .** * :.*:** ** *. : : . .* :.:.*: .. *. :*** *****.****** .* *: *:::**:*:*:* *:::.*.:. ** * : ** :***::.::* :*** ***.***:* * * *:* *:* : ::* *. *** :**.*.* .:**.. ** * **:***:**:**.******:**.*:*.*****:****:**:*:* :*. .. *.*: ** *:* :**.*. *.:*****: ** **::***.******:***:::. *****:*:* *** ****. *.*.**:*:***::*:*: *: *:* :* *::. ** *** :* ***.:* **::::* *.::* **.* .******.** *: **:**:***.*.:**** *:*:**** *** ** *** ****:**.****.*.*********. *:** * **:*:::: ..:**:.*:********:****** ******: ***:*: * ***::**::****:** **:** .* .. : **** ***** ** **::*.*.***** * ** .* .*********:*******:::* ****.**.* *:**::**: *** *.: :**: *..:**::* **:**:****::.**:**.*..** .****:* ::******:*****::*** ************************** ************.****:.*******************:************************************************:* ******** ***.**:**:****: **: *::::*********:**** **.***:: *********:** *:* .:********:***. ** * ***. . *:*:* .:* * **. ** :::.*** **:**::*.**:********* :**** *:********************: * ***:* **:** ****:*****:**.**:******* *** *:***.*. ******** *:* *****:*****:***** *:*::. ** *.* **:**.*****::. *. *:**:**. * :**:*::****:*: ******** :**.*.*** .**:*: *.* :*****.** ** ** **:* :::.* :*:**:*:*:. . : ********:****** *.:*:**:* *.:*:*:*** .* ****:***::::.:****: ***: :** **: *******::** *: .** ****:*****.**:***********.****:********************** ************.**", "identical_positions": 1001, "similar_positions": 374, "identity": "58.37%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130531-15", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63357-1", "uniprot_id": "MYO1D_RAT", "id": "Q63357-1", "name": "Unconventional myosin-Id", "aln": "MAEQESLEFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKVLNIYGRDTIEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIMISGESGAGKTEASKYIMQYIAAITNPSQRAEIERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLHSLHLQKSLSSYNYIRVGAQLKSSINDAAEFKVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFIVDGDTPLIENGKVVSVIAELLSTKADMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEVKNYDTTVHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDGMFLEALNSKLGKHGHFSSRKTCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVKKLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLVRVVLFLQKVWRGTLARMRYKRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKNMRDYGKHVKWPTPPKVLRRFEEALQSIFNRWRASQLIKTIPASDLPQVRAKVAAMEMLKGQRADLGLQRAWEGNYLASKPDTPQTSG---TFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTK-QYKVMK-TIPLYNLTGLSVSNGKDQLVVFHTKDNKDLIVCLFSK-QPTHESRIGELVGVLVNHFKSEK-RHLQVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGFILSVPGN---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SYD0-1", "uniprot_id": "MYO1D_MOUSE", "id": "Q5SYD0-1", "name": "Unconventional myosin-Id", "aln": "MAEQESLEFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKVLNIYGRDTVEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIMISGESGAGKTEASKYIMQYIAAITNPSQRAEIERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLHSLHLQKSLSSYNYIRVGAQLKSSINDAAEFKVVADAMKVIGFKPEEIQTVYKILAVILHLGNLKFIVDGDTPLIENGKVVSVIAELLSTKADMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDGMFLEALNSKLGKHGHFSSRKTCASDKILEFDRDFRIRHYAGDVVYSAIGFIDKNKDTLFQDFKRLMYNSSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVKKLIERCGFQDDVAYGKSKIFIRTPRTLFTLEELRAQMLVRVVLFLQKVWRGTLARMRYKRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKNMRDYGKHVKWPTPPKVLRRFEEALQSIFNRWRASQLIKTIPASDLPQVRAKVAAMEMLKGQRADLGLQRAWEGNYLASKPDTPQTSG---TFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTK-QYKVMK-TIPLYNLTGLSVSNGKDQLVVFHTKDNKDLIVCLFSK-QPTHESRIGELVGVLVNHFKSEK-RHLQVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGFILSVPGN---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94832-1", "uniprot_id": "MYO1D_HUMAN", "id": "O94832-1", "name": "Unconventional myosin-Id", "aln": "MAEQESLEFGKADFVLMDTVSMPEFMANLRLRFEKGRIYTFIGEVVVSVNPYKLLNIYGRDTIEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLRSLHLQKSLSSYNYIHVGAQLKSSINDAAEFRVVADAMKVIGFKPEEIQTVYKILAAILHLGNLKFVVDGDTPLIENGKVVSIIAELLSTKTDMVEKALLYRTVATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEVKNYDTTIHGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIIAILDDACMNVGKVTDEMFLEALNSKLGKHAHFSSRKLCASDKILEFDRDFRIRHYAGDVVYSVIGFIDKNKDTLFQDFKRLMYNSSNPVLKNMWPEGKLSITEVTKRPLTAATLFKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTYEKFLHRYKMISEFTWPNHDLPSDKEAVKKLIERCGFQDDVAYGKTKIFIRTPRTLFTLEELRAQMLIRIVLFLQKVWRGTLARMRYKRTKAALTIIRYYRRYKVKSYIHEVARRFHGVKTMRDYGKHVKWPSPPKVLRRFEEALQTIFNRWRASQLIKSIPASDLPQVRAKVAAVEMLKGQRADLGLQRAWEGNYLASKPDTPQTSG---TFVPVANELKRKDKYMNVLFSCHVRKVNRFSKVEDRAIFVTDRHLYKMDPTK-QYKVMK-TIPLYNLTGLSVSNGKDQLVVFHTKDNKDLIVCLFSK-QPTHESRIGELVGVLVNHFKSEK-RHLQVNVTNPVQCSLHGKKCTVSVETRLNQPQPDFTKNRSGFILSVPGN---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9L8-1", "uniprot_id": "MYO1D_DANRE", "id": "E7F9L8-1", "name": "Unconventional myosin-Id", "aln": "MAEHESLEFGKADFVLLDNVSLEEFMANLKLRFEKGRIYSYIGEVVVSVNPYRAMNIYGRDVIEQYKGRELYERPPHLFAIADAAYKAMKRRNKDTCIVISGESGAGKTEASKYIMQYIAAITNPSQRAEVERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINNYLLEKSRVIFQQEGERSFHSFYQLVKGAPDAQLRSLHIQRDPTAYNYIKVGGQLKSSINDSAEFKAVADAMKVIGFTTEEIQTVYKILATILHLGNLKFGTDGDVTLIENSKLVSVLGDLLSTKEENVEKAMLYRTVATGRDVIDKQHTHQEASYGRDALAKAIYERLFCWIVGRINDIIEVKNYDARVHGKNTVIGVLDIYGFEIFQNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQREGIPWKHIDYFNNQIIVDLVEQQHKGIFAVLDEACMNVGKVTDEMFLQALNGKLAKHAHYTSRKLSPTDKNLEFERDFRIRHYAGDVTYSVVGFIDKNKDTLFQDFKRLLYNSSNPVLKAMWPEGKLSITEVTKRPLTAATLFKNSMISLVEKLASKEPYYVRCIKPNDVKSPLLFEHERCKHQVEYLGLLENVRVRRAGFANRQTYPRFLQRYKMISEFTWPNHDLSSDKEAVKRLLQGCGFEHDVAYGKTKVFIRTPRTIFSLEEQRAEMVKRIVLFLQKVWRGTLARMRYRRMRAALIIIRAYRRYKVKSYIREVIRRFKNVRDMKDHGKHVKWPTPPKVLRKFEEALRSIYNRWWAWTLIKPLSPEKTVQIRAKVATLECLKGQRADLGLQRAWEGNYLKK--DSPGTAS---SFTLVSSDLQRKDKFMRVLFSSNVRKINRFNKAEDRALLITDRHLYKMDPLK-QYKPMK-SIPLYNVTGVSISPGKDQLVVFHTKDNRDLIVCLQGM-VPAGDSRIGELVGTLLSHFKSEK-RKLQVNTVSPIHCSMNGRKCTVVVETKISQSQPDFTKSRSGYILSVPGN---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q23978-1", "uniprot_id": "MY31D_DROME", "id": "Q23978-1", "name": "Unconventional myosin ID", "aln": "MAMQR--EAGVQDFVLLDQVSMEKFMDNLRKRFQNGSIYTYIGEVCVSMNPYRQMNIYGPETIRKYKGRELFENAPHLFAIADSAYRVLKQRQQDTCILISGESGAGKTEASKIIMKYIAAVTNAQGQNEIERVKNVLIQSNAILETFGNAKTNRNDNSSRFGKYMDIEFDYKADPVGGIITNYLLEKSRVVQQQPGERNFHSFYQLLRGANDNELRQYELQKETGKYHYLNQGS--MDILTEKSDYKGTCNAFKTLGFSTDEVQTIWRTIAAVLHLGNVEFQTIEDELVISNKQHLKSTAKLLQVTETELSTALTKRVIAAGGNVMQKDHNATQAEYGKDALAKAIYDRLFTWIISRINRAILFRGSKTQAR-FNSVIGVLDIYGFEIFDSNSFEQFCINYCNEKLQQLFIELVLKQEQEEYQREGIEWTNIEYFNNKIICDLVEQPHKGIIAIMDEACLSVGKVTDDTLLGAMDKNLSKHPHYTSRQLKPTDKELKHREDFRITHYAGDVIYNINGFIEKNKDTLYQDFKRLLHNSKDANLSEMWPEGAQDIKKTTKRPLTAGTLFQRSMADLVVTLLKKEPFYVRCIKPNDLKSSTVFDEERVEHQVRYLGLLENLRVRRAGFVHRQRYDKFLLRYKMISQYTWPNFRAGSDRDGVRVLIEEKKFAQDVKYGHTKIFIRSPRTLFALEHQRNEMIPHIVTLLQKRVRGWIVRRNFKKMKAAITIVRAYKAYKLRSYVQELANRLRKAKQMRDYGKSIQWPQPPLAGRKVEAKLHRMFDFWRANMILHKYPRSEWPQLRLQIIAATALAGRRPYWGQARRWVGDYLANSQENSGYEAYNGSIKNIRNHPADGETFQQVLFSSFVKKFNHFNKQANRAFIVSDSTIHKLDGIKNKFKDMKRTIKIRELTSISVSPGRDQLIVFHSSKNKDLVFSLESEYTPLKEDRIGEVVGIVCKKYHDLTGTELRVNVTTNISCRLDGKARIITVEAASNVEVPNFRPKEGNIIFEVPAAYCV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :. * * ****:* **: :** **: **::* **::**** **:***: :**** :.:.:******:*..********:**:.:*:*.:****:************** **:****:**.. : *:*****:*::**.:**:*********************:**:*.**:** *.*********: ** ***.*******::*. : *:. .:*:. *:*:. *. . :.: :::: ..:*:*.:**..:*:**::: :*.:*****::* . * :*.* : :. ..**... :..*: *.:*:* ::::*:*. :*.**:**:*****:*** **: *** * .:. .: : *:*************:.********************:*************** *.:*:****:** ***** ****:*::*:**:.****** :* *:: :*.** *::**: .:** *:. .**** ****** *. ***:******:******::**.:. *. ***** .*.:.*******.***:.** ** .* .***:********* **. :*:.** .***.*******:*******. ** * :** ******::****. **::.*: *:: * .** **::*:***:***:*:**. * :*: ::* :*** ** :.* .::: :**: *:* *: **::**::*: .*:: .: *:*:** ::** ** . *:.* *: ::: * * ::: . .. *:* :: : * *:*. * * * *:** . :.. . :: : .. :.: .****. *:*.*:*.* :**::::* ::*:* * ::* ** :* : ::*.:*:* *:***:***:..*:**:..* . * :.****:** : .:::. . .*:**... : * :.*: : **: . *:* .... *:.**. ", "identical_positions": 490, "similar_positions": 321, "identity": "48.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130531-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3TIW9-1", "uniprot_id": "ENPP7_MOUSE", "id": "Q3TIW9-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 7", "aln": "-MGHSAVLLCVALAILPACVTGAPVQR---QHKLLLVSFDGFRWNYDQDVDTPNLDSMAQEGVKAQYMTPAFVTMTSPCHFTLVTGKYIENHGVVHNMFYNTTSTVRLPYHATLGIQRWWDNGSIPIWITAQRQGLKTGSFFYPGGNVTYQGEAVTMSRKEGVLHNYKNETEWRGNVDTVMK-WFLEEDVSLVTLYFGEPDSTGHKYGPESQERKDMVKQVDRTVGYLRDSIKRHHLSDSLNLIITSDHGMTTVNKK-ASDLVEFHKFSNFTFQDIQFELLDYGPIGMLIPKEGMLEKVYSVLKDAHPRLHVYKKEDFPKNFHYANNPRITPLLMYSDLGYVIHGRVNVQFNNGEHGFNNQDMDMKTIFRAVGPSFKAGLEVEPFESVHVYELMCQLLGIVPEPNDGNPGILRPMLRSGSAS-------LL---------SSQHHLVALLVGILTCLAKVL--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UWV6-1", "uniprot_id": "ENPP7_HUMAN", "id": "Q6UWV6-1", "name": "Ectonucleotide pyrophosphatase/phosphodiesterase family member 7", "aln": "-MRGPAVLLTVALATLLAPGAGAPVQSQGSQNKLLLVSFDGFRWNYDQDVDTPNLDAMARDGVKARYMTPAFVTMTSPCHFTLVTGKYIENHGVVHNMYYNTTSKVKLPYHATLGIQRWWDNGSVPIWITAQRQGLRAGSFFYPGGNVTYQGVAVTRSRKEGIAHNYKNETEWRANIDTVMA-WFTEEDLDLVTLYFGEPDSTGHRYGPESPERREMVRQVDRTVGYLRESIARNHLTDRLNLIITSDHGMTTVDKR-AGDLVEFHKFPNFTFRDIEFELLDYGPNGMLLPKEGRLEKVYDALKDAHPKLHVYKKEAFPEAFHYANNPRVTPLLMYSDLGYVIHGRINVQFNNGEHGFDNKDMDMKTIFRAVGPSFRAGLEVEPFESVHVYELMCRLLGIVPEANDGHLATLLPMLHTESALPPDGRPTLLPKGRSALPPSSRPLLVMGLLGTVILLSEVA--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F6PAL8-1", "uniprot_id": "F6PAL8_DANRE", "id": "F6PAL8-1", "name": "", "aln": "MLLALSILLLVFPASLSAPARDRCTRG---RNKLLLISFDGFRWDYDRDVDTPNLDKMAVDGVKAAYVTPPYLTITSPSHFTLLSGRYIENHGVIHNVWFNTTTRQRKEYYMTQFVDDYWDNGTLPIWITAQRQGLKTGSLHFPGTAATYQNETVQEREVEPRAYDYTNETAWKENVDKVMKDWFKEQDLDFVTLYFGDPDESGHKHGPDSPERREAVKKVDRTVGYIRETAEKLGLSDHMNIIITADHGMSTVFKGDQVKEIVLTDIPGFSYKDLQFHLLDYGPTAMLLPKEGLLDKVYNALKGGHPNLHIYKKEDMPARLHYSKHPRLLPIILYADPGYVISGFYPLQNNKGEHGYDNEVMDMKPFFRAVGPDFHKNLLVGPFETVNIYPLMCHLIGIKPEINDGSLENTQHMLISNGETCDSGDDPKSSLQNVFIGLAAVVGFVFLAFVVVTSYNGYKKHKLYSKEIEKGYEDEMQGDSKQTSF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::** * * * * . .: ::****:*******:**:******** ** :**** *:**.::*:***.****::*:*******:**:::***: : *: * :: :****::***********::**:.:** .***. :* . * ::*.*** *: *:*.** ** *:*:.:******:**.:**::**:* **:: *::*******:*:: : *:* :*:***:****:** * . : : .:..*:::*::*.****** .**:**** *:***..**..**.**:**** :* :**:::**: *:::*:* **** * :* *:****::*: ****.:******.*: .* * ***:*::* ***:*:** ** *** ** : . :: :* . : ", "identical_positions": 214, "similar_positions": 125, "identity": "43.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130531-20", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NZQ0-1", "uniprot_id": "CF119_MOUSE", "id": "Q6NZQ0-1", "name": "Cilia- and flagella-associated protein 119", "aln": "MITPSSSQSLGMKVQMESEQSPKLQEELDRSPSSVDGSAIRNGTDMQTESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEKMREVLAELLELGFPEQSLRDAIILDLFSHALIFCRQQGFSPEQTSAACAMLQDLHKACVATPLGNVEECYRYFTSVLFCHGIRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLTYTGLQPLTLWPE-EKENEE-MMVVEQVATPQEEEPETVTE--------------PEQQPSEVCILQTYIKSQLSKELRQLQQLVEERLKESEERLSSKLAALEQPFQTPPSKGKTKTK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1A4V9-1", "uniprot_id": "CF119_HUMAN", "id": "A1A4V9-1", "name": "Cilia- and flagella-associated protein 119", "aln": "MLNRKTSHFLGMRVQSELEHLSELRREAGKDRSSVHGSAARTRASVRTQW---TTAAAAKADEDPGANLFPPPLPRPRICMWKYLDVHSMHQLEKTTNAE-MREVLAELLELGCPEQSLRDAITLDLFCHALIFCRQQGFSLEQTSAACALLQDLHKACIATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALEDYVVNTYFRHFKLYKYVFTPQVRLDLSLTYMGLQPPKLWPESETEKEESKEMEEQAVTPQKEELETVAP--------------PEPEPSHIHVLRAYIKTQVNKELEQLQGLVEERLKASEERLSSKLTALERPFQLPPGKGKSKTK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "U3JAD7-1", "uniprot_id": "U3JAD7_DANRE", "id": "U3JAD7-1", "name": "", "aln": "-------------------MLSRFQRQGR--------------------------------EMKPFDKIMVPQVPKARVLLWADLKHSDMEEIEKSKSTQDIERILCRALVADESQP--KQRVLLELYTNLVRFCREQNFNREQTSVLISIIKNVHQFNTETSLNNTDDCLTYCSELLICHSVRRPPFSIDLFNSEQVTHILYYFINTYMRHYFLYKYIFTPEVQLDISLSYTGIPEDTDIEPTAKSQSESPADEERETERETEMDGEVQQSSELPEMKTTEIKSPNPGLSSKSDLRTIVEKEVRNEVMRLSAQLQQELKNSADQLNNAISQLETNIQVKK--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..::.: .* ::: * :*:.*: :* *. .*..:**: ..: :..:*.. * . .: :: : *:*: : : ***:*.*. ****. ::::::*: *.*.*.::* * :.:*:**.:**********:.**: : *.:***:**: ****:***:*:**:**:* *: . ..:.* *: . : * * *: * *:: ::.:: :*: :*. :::.** * ::*.. :: ** :* ", "identical_positions": 79, "similar_positions": 107, "identity": "22.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130531-31", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A4V243-1", "uniprot_id": "A4V243_DROME", "id": "A4V243-1", "name": "Guanylate cyclase", "aln": "---------------MTRWPFNLLLLLSVAVRDCSNHRTVLTVGYLTALTG----DLKTRQGLAISGALTMALDEVNKDPNLLPNVYLDLRWNDT----KGDTVLATKAITEMICDGIATIFGPEGPCYVEAIVSQ------SRNIPMISYKCAEYRAS---AIPTFARTEPPDTQVVKSLLALLRYYAWNKFSILYED----VWSPVADLLKDQATKRNMTINHKQSFIDNRVKCCEQMLDCCRSGYWYQLVQNTMNRTRIYVFLGAANSLVDFMSSMETAGLFARGEYMVIFVDMMVYSEREAEKYLRRVDQITFMSNCHSTENFNQMARSLLVVASTPPTKDYIQFTKQVQKYSSKPPFNLEIPRLFVESNFSKFISIYAAYLYDSVKLYAWAVDKMLREETRVLTDDVIFEVASNGTRVIDTIIKNRTYMSITGSKIKIDQYGDSEGNFSVLAYKPHKWNNSNN-MPCNYHMVPVAYFHQGEE--HPEYKLINGS-------IDWPSGGEKPADEPMCGFANELCKKDDTHYTSTVAAVVLGVLLFCSGVITMSIYR-KWKIELEIEGLLWKIDPNEIKGYS----------GNEIVSSPSKVSLMSAQSYGSRWTN--------------QFVTSTGRLRGAVVRIKELKFPRKRDISREIMKEMRLLRELRHDNINSFIGASVEPTRILLVTDYCAKGSLYDIIEN-----EDIKLDDLFIASLIHDLIKGMIYIHNSQLVYHGNLKSSNCVVTSRWMLQVTDFGLHELRQCAENES---IGEHQHYRNQLWRAPELLR----NHIHGSQKGDVYAFAIIMYEIFSRKGPFGQINFEPKEIVDYVKKLPLKGEDPFRPEVESIIEAESCPDYVLACIRDCWAEDPEERPEFSVIRNRLKKMRGG----KTKNIMDQMMEMMEKYANNLEDIVTERTRLLCEEKMKTEDLLHRMLPQSVAEKLTMGQGVEPVSYDLVTIYFSDIVGFTAMSAESTPLQVVNFLNDLYTVFDRIIRGYDVYKVETIGDAYMVVSGLPIKNGDRHAGEIASMALELLHAVKQHRIAHRPNETLKLRIGMHTGPVVAGVVGLTMPRYCLFGDTVNTASRMESNGEALKIHISNKCKLALDKLGGGYITEKRGLVNMKGKGDVVTWWLTGANENAIQKKLVDMMDMPPPLFSRPRKSPKLNPDSRQPSIQAMHFCGTGSRRQSTVPRAMDGESTYSLQGSVRESPRMVSKRDRDRERPPINGLGAGHFVGGALLESAQASLSTLNHSETNETNCDMDGGSGGVSGSGSGLVRQPNALHKPLAMVRPHRIISAAQLPQLGDNDDDSADTLLRESRSLDPMPMQQLRKRHDRVKLPPSKLSKNNSRSLDTGVSLISGNPNGEVHSSQLDLDNEMTANPVDATDGYDDELGLLMRHDNGQLPALRYSGSFPNAQISIVPTGRSAGGGGGGREGGGSNCAKHLNNNCNGGVNVEDDLESPLLQRQASLSVPPEEMLAHNKRWHSLEHMDGPGGHGGNSVSYAADIDNRHPGDLDFFSGSSNQHHRSKAAGGSKLTNWMTNIFKGNGVRSGEARRVGILPSGVHGARTGFTDMAASAAARDRESIV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7JQ32-1", "uniprot_id": "GC76C_DROME", "id": "Q7JQ32-1", "name": "Receptor-type guanylate cyclase Gyc76C", "aln": "---------------MTRWPFNLLLLLSVAVRDCSNHRTVLTVGYLTALTG----DLKTRQGLAISGALTMALDEVNKDPNLLPNVYLDLRWNDT----KGDTVLATKAITEMICDGIATIFGPEGPCYVEAIVSQ------SRNIPMISYKCAEYRAS---AIPTFARTEPPDTQVVKSLLALLRYYAWNKFSILYED----VWSPVADLLKDQATKRNMTINHKQSFIDNRVKCCEQMLDCCRSGYWYQLVQNTMNRTRIYVFLGAANSLVDFMSSMETAGLFARGEYMVIFVDMMVYSEREAEKYLRRVDQITFMSNCHSTENFNQMARSLLVVASTPPTKDYIQFTKQVQKYSSKPPFNLEIPRLFVESNFSKFISIYAAYLYDSVKLYAWAVDKMLREETRVLTDDVIFEVASNGTRVIDTIIKNRTYMSITGSKIKIDQYGDSEGNFSVLAYKPHKWNNSNN-MPCNYHMVPVAYFHQGEE--HPEYKLINGS-------IDWPSGGEKPADEPMCGFANELCKKDDTHYTSTVAAVVLGVLLFCSGVITMSIYR-KWKIELEIEGLLWKIDPNEIKGYS----------GNEIVSSPSKVSLMSAQSYGSRWTN--------------QFVTSTGRLRGAVVRIKELKFPRKRDISREIMKEMRLLRELRHDNINSFIGASVEPTRILLVTDYCAKGSLYDIIEN-----EDIKLDDLFIASLIHDLIKGMIYIHNSQLVYHGNLKSSNCVVTSRWMLQVTDFGLHELRQCAENES---IGEHQHYRNQLWRAPELLR----NHIHGSQKGDVYAFAIIMYEIFSRKGPFGQINFEPKEIVDYVKKLPLKGEDPFRPEVESIIEAESCPDYVLACIRDCWAEDPEERPEFSVIRNRLKKMRGG----KTKNIMDQMMEMMEKYANNLEDIVTERTRLLCEEKMKTEDLLHRMLPQSVAEKLTMGQGVEPVSYDLVTIYFSDIVGFTAMSAESTPLQVVNFLNDLYTVFDRIIRGYDVYKVETIGDAYMVVSGLPIKNGDRHAGEIASMALELLHAVKQHRIAHRPNETLKLRIGMHTGPVVAGVVGLTMPRYCLFGDTVNTASRMESNGEALKIHISNKCKLALDKLGGGYITEKRGLVNMKGKGDVVTWWLTGANENAIQKKLVDMMDMPPPLFSRPRKSPKLNPDSRQPSIQAMHFCGTGSRRQSTVPRAMDGESTYSLQGSVRESPRMVSKRDRDRERPPINGLGAGHFVGGALLESAQASLSTLNHSETNETNCDMDGGSGGVSGSGSGLVRQPNALHKPLAMVRPHRIISAAQLPQLGDNDDDSADTLLRESRSLDPMPMQQLRKRHDRVKLPPSKLSKNNSRSLDTGVSLISGNPNGEVHSSQLDLDNEMTANPVDATDGYDDELGLLMRHDNGQLPALRYSGSFPNAQISIVPTGRSAGGGGGGREGGGSNCAKHLNNNCNGGVNVEDDLESPLLQRQASLSVPPEEMLAHNKRWHSLEHMDGPGGHGGNSVSYAADIDNRHPGDLDFFSGSSNQHHRSKAAGGSKLTNWMTNIFKGNGVRSGEARRVGILPSGVHGARTGFTDMAASAAARDRESIV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07553-1", "uniprot_id": "GCY3E_DROME", "id": "Q07553-1", "name": "Guanylate cyclase 32E", "aln": "-MPGPCASAA-----AFSCILVLLLLGCQRSNPLAAGATVSSMRRLTDTINIGFLAEYSQMRVTLGG-LPLAIEDVNKNPNLLPGKKLAFKPVDIGHKMSAYRVKPLRAMTQMREAGVTAFIGPDESCTTEALLAS------AWNTPMLSFKCSDPIVSNKSTFHTFARTLAPASKVSKSVISLLNAFHWNKFSIVVSSKPIWG-SDVARAIQELAEARNFTISHFKYISD-------YIPTTKTLSQIDKIIEETYATTRIYVFIGEHIAMVDFVRGLQNRRLLESGDYIVVSVDDEIYDSNR------------------RVNIMERNYLDPYIRKEKSKSLDKISFRSVIKISMTYP----QNPH--------IRVPIYGLHLYDSVMIYVRAITEVLRLGGDIY----------DGNLVMSHIFN-RSYHSIQGFDVYIDSNGDAEGNYTVITLQNDVGSGASIGSLAKMSMQPVGFFAYDKNSVIPEFRYIKND-----RPIQWLNG-RPPLAEPLCGFHGELCPR----KKLDWRYLVSGPLCALVVVVAIALLIKHYRYEQTLAGLLWKVDMKDVTVIN---LGEYNNPTNKNIFQICRQSILVVGEPNKRS------------------FTNIALFRGNIVAMKKIHK-KSVDITRSIRKELKLMREVRHENIINFIGASTDHGSVIIFTTYCARGSLEDVLAN-----EDLHLDHMFISSLVSDILKGMIYLHDSEIISHGNLRSSNCLIDSRWVCQISDFGLHELKAGQEEP----NKSELELKRALCMAPELLR-DAYRPGRGSQKGDVYSFGILLYEMIGRKGPWGDTAYSKEEIIQFVKCPEMLQHGVFRPALT--HTHLDIPDYIRKCLCQCWDEDPEVRPDIRLVRMHLKELQAG----LKPNIFDNMLSIMEKYAYNLEGLVQERTNLLYEEKKKTDMLLYQMLPRPVAELLKRGDPVEAECFDCVTILFSDIVGFTELCTTSTPFEVVEMLNDWYTCCDSIISNYDVYKVETIGDAYMVVSGLPLQNGSRHAGEIASLALHLLETVGNLKIRHKPTETVQLRIGVHSGPCAAGVVGQKMPRYCLFGDTVNTASRMESTGDSMRIHISEATYQLLQVIG-SYVCIERGLTSIKGKGDMRTYWLTKRQQ--------------------PELTPDLISTVD-----TLDTYCSGPRES-----MEVSVHQYCS--------------------PASNNYRLGSCNCDTKCLYSR---------RSDDNVTNSHGTSEFPKVS--------EPAQVNCNQLCVCRLNSSQMFNNRGPRSAPSITFRL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VU79-1", "uniprot_id": "Q9VU79_DROME", "id": "Q9VU79-1", "name": "Guanylate cyclase", "aln": "MFAHPCPAPAGNYHSGLLHPLLLLLFLLAFSNFRPTHGEVFTLGYLTASQRRPGNLDYNRPGLTISGAISLAVEEVNAGRLRDRGHSLQFVVAET----YGEEVVSIRQTAALWTQQVAAYIGPQETCVHEGRMAA------AFNLPMISYYCTHRDPSNKADFPTFARTRPPDTQISKSVVALLLAFNWTQVSFLYLDDASGQYQPVAETILSTLTDAGVSIRDIRTWNT-------IYHHGFMDNPFEALVEQTYANTRIYLILGHYYEHVGLMVSLQRRGILSKGDYFVVGIDIEQYDPAKPEKYLR-------GLLLEDVEPLAVQAFQSYLGIVPTASVSFATFANEVNKYMERPPFNFPNPLGPFGG--VKQISAEAAYLYDAVHLYAKALMEVLDSGGRPR----------NGSAIVAAIKG-SRYRSAMGYHVYIDENGDAAGNYTVLARG-SVRNGRNQ---TVLGLRPVGTFIHRNSSLSSISKALPHQNLKLFSPIDWVGG-TRPAAAPRCGFGGEKCVN----YTGEISAAIAGGALLLLSLVSLVLYR-NWRYEQELDSLLWKIDFREVQIHENEREQQSQKQTRHLLNHLPRRLPPQSTHPLIRTSQVSLSSNPDADFRYTTIFTPIGLYKGQLYAIKKVRK-KSVDITREMKKELKLLRDARHDNICAFIGACTDPPNICIISEYCTRGSLKDILEN-----EDVKLDNMFIASMVADIIRGVIYLHDSPIRFHGALCTSNCLVDSRWVVKLTDFGLFAFKQGIEDSSTDMQHMSAKCLKLLYRAPELLRQGPSSLVMGTQRGDAYSFGILLYEMHVRRGPFGETGLTPMQCLQKVLQPQDYLN-PYRPSLQ--PLETAF-DCVSECLRECWAERPEDRPDFKTIRTKLRPLRKG----MRPNIFDNMMAMMEKYANNLEALVDDRTDQLQEEKKKTDALLHEMLPRCVADQLKKGHKVDPEHYEQVSIYFSDIVGFTAMSAECTPLQVVDFLNDLYTCFDSIIGHYDVYKVETIGDAYMVVSGLPLRNGDLHAAEIATMSLHLLSAVSEFKIRHRPTNRLLLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTASRMESSGVPLKIHCSWQCRQLLDRLG-GYHFAERGVISMKGKGDQRTYWLLGEDE--------------------EARTRRTYERSQRRGSRALNKFIQGTIKQ-----AQEQANEYGIRSSLKQ-----------KNLPRNSLTRSSSLESPKKLRFAAGSLLEHHRYHSDEALLEVDSYTGLRRSSGGSTQSRYEETTLSLTLSCQSIEIVGGQHNKRRPSSYPTANTPLLMNHVEV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P23897-1", "uniprot_id": "GUC2C_RAT", "id": "P23897-1", "name": "Guanylyl cyclase C", "aln": "----MTSLLGLAVRLLLFQPTLM-FWASQVRQKCHNGTYEISVLMMDNSAYKEPLQNLRDAVEEGLDIVRKRLREAELNVTVNATFIYSDGLIHKSGDCRSSTCEGLDLLREITRDRKMGCVLMGPSCTYSTFQMY---LDTELNYPMISAGSFGLSCD---YKETLTRILPPARKLMYFLVDFWKVNNAPFKTFSWNSSYVYKNGSEPEDCFWYLNALEAGVSYFSEVLS-------FKDVLRRSEQFQEILMGRNRKSNVIVMCGTPETFYNVK---GDLKVADDTVVILVDLFSNHYFEDD---------------------TRAPEYMDNVLVLTLPPEKFIANASVSGRFP--------------------SERSDFSLAYLEGTLLFGHMLQTFLENG------------ESVTTPKFARAFRNLTFQGLEG-PVTLDDSGDIDNIMCLLYVSLDTRKYKVLMAYDTHKNQTIPVATSPN--------------------FIWKNH-RLPNDVPGLGPQ-----------ILMIAVFTLTGIVVVLLLIALLVLR-KYRRDHELRQKKWSHIPSENIFPL----------ETNETNHVSLKIDDDRRRDTIQRVR-------------------QCKYDKKKVILKDLKH-CDGNFSEKQKIELNKLLQSDYYNLTKFYGTVKLDTRIFGVVEYCERGSLREVLNDTISYPDGTFMDWEFKISVLNDIAKGMSYLHSSKIEVHGRLKSTNCVVDSRMVVKITDFGCNSILPP---------------KKDLWTAPEHLR-----QATISQKGDVYSFSIIAQEIILRKETFYTLSCR-DQNEKIFRVENSYGTKPFRPDLF-LETADEKELEVYLLVKSCWEEDPEKRPDFKKIESTLAKIFGLFHDQKNESYMDTLIRRLQLYSRNLEHLVEERTQLYKAERDRADHLNFMLLPRLVVKSLKEKGIVEPELYEEVTIYFSDIVGFTTICKYSTPMEVVDMLNDIYKSFDQIVDHHDVYKVETIGDAYVVASGLPMRNGNRHAVDISKMALDILSFMGTFELEHLPGLPVWIRIGVHSGPCAAGVVGIKMPRYCLFGDTVNTASRMESTGLPLRIHMSSSTIAILRRTDCQFLYEVRGETYLKGRGTETTYWLTGMKD------------------------------------------------------------------------------------QEYNLPTPPTVENQQ---------------RLQTEFSDMIVSALQKRQASGVKSRRPTR--------VASYKKGFLEYMQLNNSDHDSTYF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UWA6-1", "uniprot_id": "GUC2C_MOUSE", "id": "Q3UWA6-1", "name": "Guanylyl cyclase C", "aln": "----MTSLLGLAVRLLLFQPALMVFWASQVRQNCRNGSYEISVLMMDNSAYKEPMQNLREAVEEGLDIVRKRLREADLNVTVNATFIYSDGLIHKSGDCRSSTCEGLDLLREITRDHKMGCALMGPSCTYSTFQMY---LDTELNYPMISAGSYGLSCD---YKETLTRILPPARKLMYFLVDFWKVNNASFKPFSWNSSYVYKNGSEPEDCFWYLNALEAGVSYFSEVLN-------FKDVLRRSEQFQEILTGHNRKSNVIVMCGTPESFYDVK---GDLQVAEDTVVILVDLFSNHYFEEN---------------------TTAPEYMDNVLVLTLPSEQSTSNTSVAERFS--------------------SGRSDFSLAYLEGTLLFGHMLQTFLENG------------ENVTGPKFARAFRNLTFQGFAG-PVTLDDSGDIDNIMSLLYVSLDTRKYKVLMKYDTHKNKTIPVAENPN--------------------FIWKNH-KLPNDVPGLGPQ-----------ILMIAVFTLTGILVVLLLIALLVLR-KYRRDHALRQKKWSHIPSENIFPL----------ETNETNHISLKIDDDRRRDTIQRVR-------------------QCKYDKKKVILKDLKH-SDGNFSEKQKIDLNKLLQSDYYNLTKFYGTVKLDTRIFGVVEYCERGSLREVLNDTISYPDGTFMDWEFKISVLNDIAKGMSYLHSSKIEVHGRLKSTNCVVDSRMVVKITDFGCNSILPP---------------KKDLWTAPEHLR-----QATISQKGDVYSFAIIAQEIILRKETFYTLSCR-DHNEKIFRVENSYG-KPFRPDLF-LETADEKELEVYLLVKSCWEEDPEKRPDFKKIESTLAKIFGLFHDQKNESYMDTLIRRLQLYSRNLEHLVEERTQLYKAERDRADHLNFMLLPRLVVKSLKEKGIVEPELYEEVTIYFSDIVGFTTICKYSTPMEVVDMLNDIYKSFDQIVDHHDVYKVETIGDAYVVASGLPMRNGNRHAVDISKMALDILSFIGTFELEHLPGLPVWIRIGVHSGPCAAGVVGIKMPRYCLFGDTVNTASRMESTGLPLRIHMSSSTITILKRTDCQFLYEVRGETYLKGRGTETTYWLTGMKD------------------------------------------------------------------------------------QEYNLPSPPTVENQQ---------------RLQTEFSDMIVSALQKRQASGKKSRRPTR--------VASYKKGFLEYMQLNNSDHDSTYF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25092-1", "uniprot_id": "GUC2C_HUMAN", "id": "P25092-1", "name": "Guanylyl cyclase C", "aln": "---MKTLLLDLALWSLLFQPGWL-SFSSQVSQNCHNGSYEISVLMMGNSAFAEPLKNLEDAVNEGLEIVRGRLQNAGLNVTVNATFMYSDGLIHNSGDCRSSTCEGLDLLRKISNAQRMGCVLIGPSCTYSTFQMY---LDTELSYPMISAGSFGLSCD---YKETLTRLMSPARKLMYFLVNFWKTNDLPFKTYSWSTSYVYKNGTETEDCFWYLNALEASVSYFSHELG-------FKVVLRQDKEFQDILMDHNRKSNVIIMCGGPEFLYKLK---GDRAVAEDIVIILVDLFNDQYFEDN---------------------VTAPDYMKNVLVLTLSPGNSLLNSSFSRNLS--------------------PTKRDFALAYLNGILLFGHMLKIFLENG------------ENITTPKFAHAFRNLTFEGYDG-PVTLDDWGDVDSTMVLLYTSVDTKKYKVLLTYDTHVNKTYPVDMSPT--------------------FTWKNS-KLPNDITGRGPQ-----------ILMIAVFTLTGAVVLLLLVALLMLR-KYRKDYELRQKKWSHIPPENIFPL----------ETNETNHVSLKIDDDKRRDTIQRLR-------------------QCKYDKKRVILKDLKH-NDGNFTEKQKIELNKLLQIDYYNLTKFYGTVKLDTMIFGVIEYCERGSLREVLNDTISYPDGTFMDWEFKISVLYDIAKGMSYLHSSKTEVHGRLKSTNCVVDSRMVVKITDFGCNSILPP---------------KKDLWTAPEHLR-----QANISQKGDVYSYGIIAQEIILRKETFYTLSCR-DRNEKIFRVENSNGMKPFRPDLF-LETAEEKELEVYLLVKNCWEEDPEKRPDFKKIETTLAKIFGLFHDQKNESYMDTLIRRLQLYSRNLEHLVEERTQLYKAERDRADRLNFMLLPRLVVKSLKEKGFVEPELYEEVTIYFSDIVGFTTICKYSTPMEVVDMLNDIYKSFDHIVDHHDVYKVETIGDAYMVASGLPKRNGNRHAIDIAKMALEILSFMGTFELEHLPGLPIWIRIGVHSGPCAAGVVGIKMPRYCLFGDTVNTASRMESTGLPLRIHVSGSTIAILKRTECQFLYEVRGETYLKGRGNETTYWLTGMKD------------------------------------------------------------------------------------QKFNLPTPPTVENQQ---------------RLQAEFSDMIANSLQKRQAAGIRSQKPRR--------VASYKKGTLEYLQLNTTDKESTYF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6Z2-1", "uniprot_id": "A0ACD6B6Z2_DANRE", "id": "A0ACD6B6Z2-1", "name": "Guanylate cyclase", "aln": "--------MDYRIWLFVCFSWAFLKQSLLMKESCLNGTLLINVVLLDDDVSPWSINFVKPAVMRAVESDSEINFKDGVNLSV--SFRGFQTIYYQKTGCSSSACEGVEILNDLANAGEEGCALLGPTCTYATFQMADLEIGLNLNMPIISAGSFGLSCD---LKRDLTRLLPPARKISSFFINFWKFHDP--VKPKWETAYLYKKPDNTEDCFWYINALEVSNGGFSPSLQ-------EIEVIRNKEDLTKAMAKHNRESNLFILCGTPDDIMDLKN--GTTDYDSEIAFLLIDLYNDIYYKGQ---------------------SNT--FMRNVLVLTMPN---TRKYTIDTSGN--------------------NTMNDYIAAYHDAVLLFGQVMRNIQKSGSLDI--------QDMESVSMN-YFRNVSFTGIAG-EYQLDQHGDRDLMFSLIYTNNNN-QYNILYQFNTSNNKTGLKDSSPS--------------------FIWQS--RLPNDSPSKGLS-----------VIEIIVIVLCTVIGIMGTLAFIFYW-QNRYYHHM-QKRWSHISSQLITPL----------ELNEWNMISLKIEEDSTENSTYILR-------------------RARYDKKIVILKEFRL-TDGSFTEKQRIELNTLLKIDYCNLTKFYGTVKFDNEYFGVFEYGERGSLRYVLDDKISYPEETFMDWQFKISVMYDIAKGMSYLHTSNIAVHGRLKSTNCVVDNRMVVKIADFGFNTIVSP---------------SEDLWTAPEHLR-----KPGISQKGDVYSFAIISQEIMMRKCTFYTNTCS-DRAEKLARVQYPSTTSFFRPDLN-FESTSESEEEVCMLIRNCWDEDPDRRPDFKKIEIALWKIVSR-DNQEHESYMENLIRRLQMYSRNLERLVEERTALYKAERDRADCLNFMLLPGPVVRSLKETGKVEPELFDEVTIYFSDIVGFTTLCHFSTPMEVVDMLNDIYKNFDSILDNHDVYKVETIGDAYMVVSGLPRRNGNRHAKDICLMALDILAFMGTIQLSHLPGIPVWIRIGVHSGPCAAGVVGIKMPRYCLFGDTVNTASRMESTGLPLRIHVSQSTINILQRTDCKFEYEERGETFLKGKGKEMTYWLTGVTG------------------------------------------------------------------------------------ENYNLPTPPTAENFQ---------------NLQQDLSEMIKTCLQKRPSGLWRRKTLSARHRKLMVGVEMETTDQPEYLHLATGDFLSTYL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZB47-1", "uniprot_id": "A1ZB47_DROME", "id": "A1ZB47-1", "name": "guanylate cyclase", "aln": "--------------------------------------------------------MLNGKAHKSGENPDPSPCPAGGSRMPTPSVKIDISTCQS-----NRPMESRTAPDDVNPSGEGGLLLVPTHHNLQLDKIS----VRSISSEDISNGGSGRCCN------AAARNPAIKTGRRLQLMQMIILPFIPILALIVQTS----------------------------------------VTLQEILEYRSAVADIETQVTIATDLGKVVTRLQLER---------------------------------------------------------------------------------------------------------------------------------------------------------------SEVAFYIFTNGSKQRANLTLRFANTDHALNNMTTWSEISVPTAPDEDEDDR--------------------------------------------------------------------EMMLNRYEFQSRLNEFRDRVRLEPEESSITE----------VMNWYTSINRGLLHHLS--------------------------------------EQIKETDNSGVWRYLVGFKNLLKSIECQNIATSFGIRYYGRGSLTAENFVSYVRYEFMAREMIN----STLNYAPMLKNMYTNITSTKKFHRAKQMGTTLLKNNPNVSNERSAIEYYEL--------------------------MNNYTDDLR-----ILQKALRRLIKEYVDKTLVEADRKEAIGIAILVVVLIVSPVII----------------------------------------------------------------VLVKNAAATIQLYALNLS----QKAKELKREKRKSDSLLFQMLPPSVAMQLKQTQQVPAELYEAVTIYFSDIVGFTEIAADCTPLEVVTFLNSIYRVFDERIECYDVYKVETIGDSYMVASGLPVKNGNKHISEIATMALDLLDASSVFRIPRAGDEFVQIRCGVHTGPVVAGIVGTKMPRYCLFGDTVNTASRMESTGEAQKIHITEEMHDSLQQVG-GFRTEHRGLIDVKGKGLMSTYWLTCKDG--------------------------------------------------------------------------------------------------------------------PVRAREEISWR-------------------------ADIQPVFLDHLKLHPPTDYKLPKRK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . :* . :* . .: : : : * . : *. : . : . . : : . :..: . .. . . : . *: * : : : :: . : . :* : * .. : .* : :: : .: ** : : : *: . . .. :: *: **. ::: *: ::: * . :** *. *. * . :: *:* ******** :. .**::** :**. * * : :**********:*:*.**** :**. * :*. ::*.:* .: : : :* *:*:** **:** .*******************.* . :** : * : ** :**:* *:** : : . ", "identical_positions": 102, "similar_positions": 122, "identity": "6.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130531-36", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ULH7-1", "uniprot_id": "MRTFB_HUMAN", "id": "Q9ULH7-1", "name": "Myocardin-related transcription factor B", "aln": "MIDSSKKQQQGFPEILTAGDFEP-----LKEKECLEGSNQKSLK--------------EVLQLRLQQRRTREQLVDQGIMPPLKSPAAFHEQIKSLERARTENFLKHKIRSRPDRSELVRMHILEETFAEPSLQATQMKLKRARLADDLNEKIAQRPGPMELVEKNILPVDSSVKEAIIGVGKEDYPHTQGDFSFDEDSSDALSPDQPASQESQGSAASPSEPKVSESPSPVTTNTPAQFASVSPTVPEFLKTPPTADQPPPRPAAPVLPTNTVSSAKPGPALVKQSHPKNPNDKHRSKKCKDPKPRVKKLKYHQYIPPDQKGEKNEPQMDSNYARLLQQQQLFLQLQILSQQKQ-----HYNYQTILPAPFKPLNDKNSNSGNSALNNA------------TPNTPRQNTSTPVRKPGPLPSSLDDLKVSELKTELKLRGLPVSGTKPDLIERLKPYQEVNSSGLAAGGIVAVSSSAIVTSNPEVTVALPVTTLHNTVTSSVSTLKAELPPTGTSNATRVENVHSPLPISPSPSEQSSLSTDDTNMADTFTEIMTMMSPSQFLSSSPLRMTNNEDSLSPTSSTLSNLELDAAEKDRKLQEKEKQIEELKRKLEQEQKLVEVLKMQLEVEKRGQQQRPLEAQPSAPGHSVK-SDQKHGSLGSSIKDEASLPDCSSSRQPIPVASHAVGQPVSTGGQTLVAKKAVVIKQEVPVGQAEQQSVVSQFYVSSQGQPPPAVVAQPQALLTTQT--AQLLLPVSIQGSSVTSVQLPVGSLKLQTSPQAGMQTQPQIATAAQIPTAALASGLAPTVPQTQDTFPQHVLSQPQQVRKVFTNSASSNTVLPYQRHPAPAVQQPFINKASNSVLQSRNAPLPS-LQNGPNTPNKPSSPPPPQQFVVQHSLFGSPVAKTKDPPRYEEAIKQTRSTQ-APLPEISNAHSQQMDDLFDILIKSGEISLPIKEEPSPISKMRPVTASITTMPVNTVVSRPPPQVQMAPP--VSLEPMGSLSAS-LENQLEAFLDGTLPSANEIPPLQSSSEDREPFSLIEDLQNDLLSHSGMLDHSHSPMETSETQFAAGTPCLSLDLSDSNLDNMEWLDITMPNSSSGLTPLSTTAPSMFSADFLDPQDLPLPWD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P59759-1", "uniprot_id": "MRTFB_MOUSE", "id": "P59759-1", "name": "Myocardin-related transcription factor B", "aln": "MIDSSKKQPQGFPEILTAEDFEP-----FKEKECLEGSNQKSLK--------------EVLQLRLQQRRTREQLVDQGIMPPLKSPAAFHEQIKSLERARTENFLKHKIRSRPDRSELVRMHILEETFAEPSLQATQMKLKRARLADDLNEKIAQRPGPMELVEKNILPVDSSVKEAIIGVVKEDYPHTHGEFSFDEDSSDALSPDQPASQESQGSAASPSEPKVSASPPPVTASTPAQFTSVSPAVPEFLKTPLTADQPPTRSTAPVLPTNTVSSAKSGPMLVKQSHPKNPNDKHRSKKCKDPKPRVKKLKYHQYIPPNQKGEKSEPQMDSNYARLLQQQQLFLQLQILSQQQQQQQQQHYNYQTILPAPIK--TDKNSSSGSNSGS---------------------SSSMPARRPGPLPSSLDDLKVSELKTELKLRGLPVSGTKPDLIERLKPYQEVTSSNLATGSIVAVSSATIVTSNPEVTVALPVTTLHNAVTSSVSTFKADLALPATSSVPHVENAHSPLPISPSPSEQSSLSTDDTNMTDTFTEIMTMMSPSQLLCSSPLRVVSHDDSLSPSSSTLSTLELDAAEKDRKLQEKEKQIEELKRKLEQEQKLVEVLKMQLEVEKRGQQ-RPPDPQPSDPPHPFNTSDPKHGSVGSSIKDEASLPDCSSPQQPITVPGHSVGQPISTGSQTLVAKKTVVVKQEVPMAQAEQQNVVSQFYLSSQGQPP-ALVAQPQALLTTQT--TQLLLPVSIQGSNVTSVQLPVGSLQLQTPAQGRVQAQPHVAAATQVPAAALPSALTSALPQKQEAFPQHVLGQPQPVRKVFTNSAP-NTVLQYQRQPGPTNQQPFVSKTSNPALQSRTAPLAP-LQNGPSLASKPSSPPPPQQFVVQHSLFATPITKTKDPPRYEEAIKQTRSTQ-PALPEVSSVHSQQMDDLFDILIKSGEISFPIKEEPSPISKMKPVTASITTMPVNTVVSRPPPQVQIAPP--VSLEPVNSLSAS-LENQLEAFLDGTLPSATDTGPLQNSSEDRESFSLIEDLQNDLLSHSSMLYQSHSPMETSEAQLVSGTPCLSLDLSDSNLDNMEWLDITMPTTSSGLTPLSTTAPSMFSADFLDPQDLPLPWD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58GXQ2-1", "uniprot_id": "A0AC58GXQ2_DANRE", "id": "A0AC58GXQ2-1", "name": "", "aln": "MENPEERGPCAFFTKFCYQEPTLRYSGRVKGMTCLGLETHQTCRGNFLSGSVTCCSSLRVLQLRLQQRRTREQLVEQGIMPPLKSPAAFHEQIRSLERARTENFLKHKIRSRPERAELVRMHILQETLAEPSLQATQLRLKRARLADDLNEKIAQRPGPMELVEKNILPVDSSLKEAIIDG-QMQYPRTLEDL-IDEDSGDAFSPEQPASQESQGSAASPAEVRTMEETSPLPNNLLQHFPAVTTTSTDFLKPFSTVEQSVS-PPAPIPQLVTVAPVKSGPTLVKQSQPKLPGDKSRSKKSKESKPRVKKLKYHQYIPPDQKQEPDQAPMDSSYARLLQQQQLFLQLQILSQQQQQ----HYNYQTILPAPLKPVIEGQNSSATVAINNANSLPASIVVSLPTTTPVRPNSTLSNRKAGILPANLEEMKVAELKMELKLRGLPVSGTKTDLIERLKPFQEN-----------------------------PITTAPN----------------NSSTGPKTQPCGTPMEVSSTTTTISPIQLASTTLSSTPPVSP---SSSELLSREDMSVEGQAETQN---RCLIKANAVPEEQDRRLHEKERQIEELLRKLEQEQKLVEELKMQLEVEK------------------------RSGVVPSVENNNVSGP-------SIMLASVKAENTVPPNCKLNSHTTTTLVKLEEAHPNQVTTAPLRQFIISHQGVPQ--VIGQPQTLLTTQHGGTQILLPMPLAN-NTTTIQLPNANVKLQPVLQAVSTPGTGLIQTPQLQSTKAESPTSQQLLSHNHIVQTLSVGTTE--RSGFQHSTS-------ENQAGLEIPQCFLSSSPENRTSPQTSPIPSSLING--QLNKAS-------FIQQCPVFN-QAPKNREPPRYEEAVKQTRSLQNPTISEFSTVTSQQMDDLFDILIESGEITPFSQQDPS-VPKMMPVTASITTLPISTALSRPPAQVQMAPPPTLMVEPLPSLASLDSDNQLEALLEGTLVGDTEP--------EQRTLCLLEELQN------QMLDQPNSPMDTSELGFSDPPAQSSFSLQDTGLDNMEWLDLTMPGPIGGLNPLG------IASEFLDTHDLQLHWD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :..:: .* : : .* ** ..::: : .****************:*****************:*******************:*:********:**:*********::**********************************:*****. : :**:* :: :****.**:**:**************:* :. ...*:. . :*.:*:.: .:***. *.:*. . ..**: **:..*.** *****:** *.** ****.*:.***************:** * .:. ***.********************:* ***********:* : :..*.. : . .:: . *:.* **:.*:::**:*** *************.********:** *:** * :*. .:.: :*: :*.:.: *.:. .*.::.* . *.*::*. . : : .: :: . * . : . *:**:*:***:***** *********** ********* : * : * :::.* * .* :.. . :.:... : ..:.::* * . : : ** :* ** * ::.***:***** :*:***:.: . ..*::*** ..::**. *. . . : :.*: :: * : : . :. . :. .: *. * :*:. :.:.. * *:..:.: ..:.:*:.. * ** .*.* *: * .:* .*.::*******:***** * ..:.*.*.. ************:****: :::** :.** ********:*:.*.:****.***:*** : :**: **:: :*****:*:*** . .: ::..:.*:*:*** ** :.:***:*** : .. *:.*.*:.********:*** . .**.**. ::::***.:** * **", "identical_positions": 462, "similar_positions": 302, "identity": "40.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130531-41", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVT0-1", "uniprot_id": "AGRF5_RAT", "id": "Q9WVT0-1", "name": "Adhesion G protein-coupled receptor F5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKSSRTVTLYFVLIVICSSEATWSRPAEPIVHPLILQEHELAGEELLRPKRAVAVGGPVAEEYTVDVEISFENVSFLESIRAHLNSLRFPVQGNG----TDILSMAMTTVCTPTGNDLLCFCEKGYQWPEERCLSSLTCQEHDSALPGRYCNCLKGLPPQGPFCQLPETYITLKIKVRLNIGFQEDLENTSSALYRSYKTDLERAFRAGYRTLPGFRSVTVTQFTKGSVVVDYIVEVASAPLPGSIHKANEQVIQNLNQTYKMDYNSFQGTPSNETKFTVTPEFIFEGDNVTLECESEFVSSNTSWFYGEKRSDIQNSDKFSIHTSIINNISLVTRLTIFNFTQHDAGLYGCNVTLDIFEYGTVRKLDVTPIRILAKEERKVVCDNNPISLNCCSENIANWSRIEWKQEGKINIE-------------GTPETDLESSCSTYTLKADGTQCPSGSSGTTVIYTCEFVSVYGAKGSKNIAVTFTSVANLTITPDPISVSEGQSFSITCLSDVSSFDEVYWNTSAGIKIHP-----------------RFYTMRRYRDGAESVLTVKTSTREWNGTYHCIFRYKNSYSIATKDVTVHPLPLESDIMMDPLEASGLCTSSHQFKC--------CIEENDGEEYIVTFHVDSSSFPAEREVIGKQACYTYSLPGKLPSRCPKDIDVFCHFTNAANSSVRSPSMKLTLVPGKNITCQDPIIGIGEPGKVIQKLCQFAGV-----SRSPGQTIGGTVTYKCVGSQWKEETRACISAPINGLLQLAKALIKSPSQDQKLPKYLRDLSVSTGKEEQDIRSSPGSLGAIISILDLLSTVPTQVNSEMMRDILATINVILDKSTLNSWEKLLQQQSNQSSQFLQSVERFSKALELGDSTPPFLFHPNVQMKSMVIKRGHAQMYQQKFVFTD-------------SDLWGDVAIDECQLGSLQPD----SSIVTVAFPTLKAILAQDGQRKTPS----NSLVMTTTVSHNIVKPF-RISMTFKNNHRS-GGKPQCVFWNFSLANNTGGWDSSGCTVEDDGRDNRDRVFCKCNHLTSFSILMSPDSPDPGSLLKILLDIISYIGLGFSIVSLAACLVVEAMVWKSVTKNR-----TSYMRHICIVNIALCLLIADIWFIVAGAIHDGHYPLNETACVAATFFIHFFYLSVFFWMLTLGLMLFYRLIFILHDASKSTQKAIAFSLGYGCPLIISSITVGVTQPQEVYMRKNACWLNWEDTRALLAFAIPALIIVVVNVSITVVVITKILRPSVGDKPGKQEKSSLFQISKSIGVLTPLLGLTWGFGLATVIQGSNAVFHIIFTLLNAFQGLFILLFGCLWDQKVQEALLHKFSLSRWSSQHSKSTSLGSSTPVFSMSSPISRRFNNLFGKTGTYNVSTPETTSSSVENSSSAYSLLN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G5E8Q8-1", "uniprot_id": "AGRF5_MOUSE", "id": "G5E8Q8-1", "name": "Adhesion G protein-coupled receptor F5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRSPRTFTFYFLLLVICSSEAALSTPTEPIVQPSILQEHELAGEELLRPKRAAAAGDRVAEEYMVDIEISFENVSFLESIRAHLNNLSFPIRGTE----ADILNIAMTTVCTPAGNDLLCFCEKGYQWSEERCLHSLTCQDYDSALPGGYCSCLKGLPPQGPFCQLPEAFITLKLKVRLNIGFQEDLKNTSSALYRSYKTDLERAFRAGYRTLPGFRSVTVTQFTKGSVVVNYVVRVTSAPLPGSIHKANEQVIQNLNHTYKMDYNSFQGTPSNETKFTVIPEFIFEGDNVTLECETEFVTSNTSWYYGEKRSDIQNSDKYSIHTTVINNISLITRLTIYNFTQHDAGMYGCNVTLDIFEYGTVRKLDVTPIRILAKEERKVVCDNHPISLNCCSENIANWSSIEWKQEGKISIL-------------GNPESDLESSCSTYTLKADGTQCPSGSSGTTVIYTCEFVSAYGARGSKNIAVTFTSVANLTITRDPISVSEGQSFSITCLSDVSSFDEVYWNTSAGIKIHP-----------------RFYTMRRYQDGAESVLMVKTSTREWNGTYHCIFRYKNSYSIATKDVTVHPLPLVSDIMMDPLEASGLCTSSHQFKC--------CVEEDAGEEYAVTFHVDSSSFPAEREVIGKQACYTYSLPANLP-RCPKDIAVFCHFTNAANSSVRSPSMKLKLIPRENVTCQDPIIGIGDPGKVIQKLCQFSGV-----YGSPGQAIGGTVTYKCVGTQWKEESRACISAPINGLLQVAKALIKSPTQDQKLPTYLRDLSVSAGKEEQDIRSSPGSLGAIISILDLLSTVPTQVNSEMMRDILATINVILDKSALNSWEKLLQQQSNQSSQFLHSVERFSQALQLGDSTPPFLAHPNVQMKSMVIKRGHPQIYQQQFIFKD-------------SDLWGDVAIDECQLGNLQPD----SSIVTVAFPTLKAILAQDVQRKTSS----NSLVMTTTVSHNIVKPF-RISMTFKNNHRS-GGKPQCVFWNFSLANNTGGWDSSGCSVEDDGRDNRDRVFCKCNHLTSFSILMSPDSPDPGSLLKILLDIISYIGLGFSIVSLAACLVVEAMVWKSVTKNR-----TSYMRHICIVNIAFCLLIADIWFIVAGAIHDGRYPLNETACVAATFFIHFFYLSVFFWMLTLGLMLFYRLIFILHDASKSTQKAIAFSLGYGCPLIISSITVGVTQPQEVYMRKNACWLNWEDTRALLAFAIPALIIVVVNVSITVVVITKILRPSIGDKPGKQEKSSLFQISKSIGVLTPLLGLTWGFGLATVIQGSNAVFHIIFTLLNAFQGLFILLFGCLWDQKVQEALLHKFSLSRWSSQHSKSTSIGSSTPVFSMSSPISRRFNNLFGKTGTYNVSTPETTSSSLENSSSAYSLLN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IZF2-1", "uniprot_id": "AGRF5_HUMAN", "id": "Q8IZF2-1", "name": "Adhesion G protein-coupled receptor F5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKSPRRTTLCLMFIVIYSSKAALNWNYESTIHPLSLHEHEPAGEEALRQKRAVATKSPTAEEYTVNIEISFENASFLDPIKAYLNSLSFPIHGNNTDQITDILSINVTTVCRPAGNEIWCSCETGYGWPRERCLHNLICQERDVFLPGHHCSCLKELPPNGPFCLLQED-VTLNMRVRLNVGFQEDLMNTSSALYRSYKTDLETAFRKGYGILPGFKGVTVTGFKSGSVVVTYEVKTTPPSLE-LIHKANEQVVQSLNQTYKMDYNSFQAVTINESNFFVTPEIIFEGDTVSLVCEKEVLSSNVSWRYEEQQLEIQNSSRFSIYTALFNNMTSVSKLTIHNITPGDAGEYVCKLILDIFEYECKKKIDVMPIQILANEEMKVMCDNNPVSLNCCSQGNVNWSKVEWKQEGKINIP-------------GTPETDIDSSCSRYTLKADGTQCPSGSSGTTVIYTCEFISAYGARGSANIKVTFISVANLTITPDPISVSEGQNFSIKCISDVSNYDEVYWNTSAGIKIYQ-----------------RFYTTRRYLDGAESVLTVKTSTREWNGTYHCIFRYKNSYSIATKDVIVHPLPLKLNIMVDPLEATVSCSGSHHIKC--------CIEEDG--DYKVTFHTGSSSLPAAKEVNKKQVCYKHNFNASSVSWCSKTVDVCCHFTNAANNSVWSPSMKLNLVPGENITCQDPVIGVGEPGKVIQKLCRFSNV-----PSSPESPIGGTITYKCVGSQWEEKRNDCISAPINSLLQMAKALIKSPSQDEMLPTYLKDLSISIDKAEHEISSSPGSLGAIINILDLLSTVPTQVNSEMMTHVLSTVNVILGKPVLNTWKVLQQQWTNQSSQLLHSVERFSQALQSGDSPPLSFSQTNVQMSSMVIKSSHPETYQQRFVFPY-------------FDLWGNVVIDKSYLENLQSD----SSIVTMAFPTLQAILAQDIQENNFA----ESLVMTTTVSHNTTMPF-RISMTFKNNSPS-GGETKCVFWNFRLANNTGGWDSSGCYVEEGDGDN---VTCICDHLTSFSILMSPDSPDPSSLLGILLDIISYVGVGFSILSLAACLVVEAVVWKSVTKNR-----TSYMRHTCIVNIAASLLVANTWFIVVAAIQDNRYILCKTACVAATFFIHFFYLSVFFWMLTLGLMLFYRLVFILHETSRSTQKAIAFCLGYGCPLAISVITLGATQPREVYTRKNVCWLNWEDTKALLAFAIPALIIVVVNITITIVVITKILRPSIGDKPCKQEKSSLFQISKSIGVLTPLLGLTWGFGLTTVFPGTNLVFHIIFAILNVFQGLFILLFGCLWDLKVQEALLNKFSLSRWSSQHSKSTSLGSSTPVFSMSSPISRRFNNLFGKTGTYNVSTPEATSSSLENSSSASSLLN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D2L6-1", "uniprot_id": "AGRF4_MOUSE", "id": "Q9D2L6-1", "name": "Adhesion G protein-coupled receptor F4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKPWIAMVCCLVFFLTTECSHSK---------------------------------PKTHRKDEDKFQISLQKHEFR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PRQGKCDGLCSSSSSCNQSCP------WNFRG-----------------------EIVFTCNQNKWQKTIETCTSLSVDTLFQRIHPAASLS-------------------------------------LASSSVFPMSLIGNAAPVHIGN-----------------VFQGIQKYCP---------------------------------------------------------------------------------------------------------------------------EDYVCIVDAVKSSAVTSGNIAFIVELLKNISSNLQTSGIHDN----------------------------------------------------------------------------------------------------------------VNWKKMKNYGKVANHILGPTAISNWAFIAN--KNASSDLLESVNSFAKKLQIQGKSESIVDELFIQTKGSRISHSSSEHSLSLSVPRY-------------NATEDVLVVIEIPRQALQELSFNASQAIVVAFPTLGAILKEVHRPNTSL----QKPIDDLILSLVLPEGLNEIILTFDKINKSQSTSSQCVSWDP----ATGQWDESPCTVMSDINSTVKCRCRHTKAVTSFSILMSSKP-----VKNTILNHITFIGLSISIFSLVLCLVIEAIVWSRVVVTE-----ISYMRHVCIVNIAVSLLTANVWFIIGSNFSAN-VQEDHKWCVAVTFLCHFFFLSLFFWMLFKALLIVYGILVVFRRMMKSRMMAIGFAIGYGCPLVIAVITVTVTEPGEGYTRKDACWLNWNQTKALFAFAIPALAIVAVNLLVVLAVAINTQRPLIGSSKS-QDMAIVFRISKNVAILTPLLGLTWGFGLTTLLEGVHLVFHIIFALLNAFQGFFILLFGTIMDHKIRDALRMRVSSLKGKSRAAEKVSLSPANGSRILNR---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32T7A9-1", "uniprot_id": "A0AB32T7A9_DANRE", "id": "A0AB32T7A9-1", "name": "", "aln": "MASGGKISIYLFGIIMAVVLNHECVAEVLDFSDISLDLQFSYSDGAAHHIRRRSTDQVQYVMVVEVNVSDIEALNQIRTSVATVPLPFQADNSTEITAVNISTVCSLNETQYQCKCEGLFVWPNDTCHVYQACDAISNGSCTCINDLPADGQFCQDVDKCLVNPPVCGPNSNCTNTMGSYSCSCLSGFTATNPNLTISIDNICTAPSITTPTPSSPTQSTTAGPLFVYESEIDISLFDISSANRLESLITSYQPPYSLGSMNILELNITTVCGLNGTEYDCQCAANHVWSSNNCTTYQACDNIVGGTCGCIRALPSAGPLCQRDINECQPSPSVCGPNSSCTNEIGSYSCACLNGFTPTIFNLSVSMNNTCRESLTSPTTTPATTPTSTLTTTPTTRPLSSSTTVPLFVYDSEIEIDLFFDYPTSSIRDLFTRVNNFLPYTLNN----VNLLSVDMTTVCDLNGTDFDCKCEVAHVWPSNTCKAYQVCDN----IVGGTCGCIQALPSNGTLCQQDINECQQTPSVCGPNSTCTNVIGSYNCLCLPGFIPANPNLLASINN----TCIATAPLTPTPSTPTTKAPVFVYESDIEIDLFSDYPMSSLRNLLTGIPLPYTLSIINLLSVNITTVCDLNGTGFDCKCEANHVWPSSTCTTYQVCDSIVGGTCGCIQTLPSNGSLCQQDINECQPSPSVCGPNSICNN-EIGSYSCSCLNGFTPANSNLLVSSNNKCTAPTTTPQPSPQPSPQPSTQPTPQTTPQTTTPPQPTPTTPQPTTTTTTTPEPTTATTTTPQPTTTTQPTTTTTTTTTTTTTTTTVATKVITMSLKMDQTFDTNLADSTTKTFKDLSGKLESSIDSSYSSNLKGYVSKSVKVNAYRPGSVFADYTISATSSNLDFSSANAALSSSLQAQGIILAADAFAQSDQKDFITSQVYPQQKLELICTQPDFAQGQITWKVNNKDPDKNQYSLSSDNRTLTANSVTESNSGQYSCITQRTTIPYIQWQNIAVKQLPNINVGNNYRVVPCPGSSVLKCSVDAGYSVEWVQGETVQVSESAADGITLNYASQIGNCTQEQTFTCRLKGLPALLIYGYSQSSVIVKNTDQQYDCQNEELGLGNQNEQRNGICPTGTKGIITYECDSKAWRPIKENCILGVISDLLIQIPVLQVGQIPSFLSNLSFATEQNNINITQSAATVKAIVDILSQIANLAQTALIGPPVMNSFLKTLDIIVSTNSTETWNTLNNDNTTENTNIKLLKATETISDRLIDQFTVNLTSIQLSRTTVNSSLSVTSTLSNSTTEIVIPQVFGPTTATIIIFTTLDNILPTRNISNNNSSDISDQRINGDVVVVKVDKTVNNISFAFDITNQS-LGNPQCVFWNFN----LSAWDSTGCEVKQVGNDS-GIITCECNHTTSFSILMSPFI-----LDSLILAYITYIGVTISMISLVLCLIIEAIVWRSVTSARGVTVVSSYMRHISLVNIALSLLIANVCFIIGAAISDLEKPTPVGRCSPVVFFIHFFYLAVFFWMLISGMLLLYMTVMVFGQMSRIKMIAISFPVGYGAPLLIASITVASTAGPQNYVSKQACWLNWNESRALLAFVIPALTIVAINLVVLVVVLYKMLGTGVGAATQPSEKNTFFVVVRCVAFLTPLFGLTWGFGIGTMLS-SALGVHVLFTLLNAFQGFFILLFGTILDAKVREALRGKLQIDKLTSRITQSTSGGASSSAGQRGPRRNVYNVSDPNNTSRFTSEGVSGSYSAVDT---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. : . . ..:: :: : * : . . : :.. . : .: : * : :. * ..:. :: * . * . . . . : : : * : . : . : . ..:*.::: : . . . : . :. . .: : : : : *.** ** :. :. : : . .* ::*. * ..:** *: . **.: * * . .. . ********. : :* *:::*: :*:.**. **::**:** *. . ***** .:**** .** *: **: . : * ...*: ***:*::***** .:::.* :.:: : **.* :***.** *: **: * : * *:.*****::::**:**.**** **.:*: : :.* : . :* .: .* : : :..****:*******: *:: .*::*::**.***:****** : * *:::** :.. : .*: ::..* ..:. . ", "identical_positions": 133, "similar_positions": 194, "identity": "7.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130531-42", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LUE3-1", "uniprot_id": "A0ABK0LUE3_RAT", "id": "A0ABK0LUE3-1", "name": "", "aln": "MLQQILQDMYIDPELLAELSDVQKHILFYKMREEQLRRWREREAWDALAQAEGLRPAKVKRASNKHIQWLLGADGEVWVWVMGEGPGDKPYEEISEELIAERARLQAQKEAEELWRQKEAEITKKFRDALANEKARILAEKWKVEMEDRKAAKVLEE--RIHEEFKRKEEEERRRGEEQIRLQEEQRAKELYWTLKQAQLHCQDSENEEREWEEQLRRSKAADEERSRRAQRARDEYRRHSLRAIQKGTVAGLSTMFQ------------------------ELGQNHEQEA-----RLYHQLPGTRPPSPLTG---PDRTWERPLRPLSREVIVRWFKEEQLPRRAGFERNTKSIAPWFHGIISRENAEDLLENMTEGAFLVRVSEKIWGYTLSYRLQRGFKHFLVDASGDFYSFLGVDPNRHATLTDLIDFHKEEIITVSGGELLQEPCGQRDSPPDYHLLFE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6X942-1", "uniprot_id": "SH24B_MOUSE", "id": "A6X942-1", "name": "SH2 domain-containing protein 4B", "aln": "MLQQILQDMYIDPELLAELSDVQKHILFYKMREEQLRRWREREAWDALAQAEGLRPAKVKRASNKHLQWLLGADGEVWVWVMGEGPGDKPYEEISEELIAERARLQAQKEAEELWRQKEAEITKKFRDALANEKARILAEKWKVEMEDRKAAKILEE--RIHEEFKRKEEEERRRGEEQIRLQEEQRAKELYWTLKQAQLHSQASENEEREWEEQLRRSKAADEERSRRAQRARDEYRRHSLRAIQKGTVAGLSTMFQ------------------------ELGQNHEQEA-----RLYHQLPDTSPPSPLTG---PDRTWERPLRPLSREVIVRWFKEEQLPRRAGFERNTKSIAPWFHGIISRESAEDLLENMTEGAFLVRVSEKIWGYTLSYRLQRGFKHFLVDASGDFYSFLGVDPNRHATLTDLIDFHKEEIITVSGGELLQEPCGQRDSPPDYHLLFE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SQS7-1", "uniprot_id": "SH24B_HUMAN", "id": "Q5SQS7-1", "name": "SH2 domain-containing protein 4B", "aln": "MLQQILHDMYIDPELLAELSDVQKHILFYKMREEQLRRWKERETWEALAQDEGLRPPKTKRASDKHIQWLLGADGEVWVWIMGEGPGDKPYEEISEELIAERARLQAQREAEELWRQKEAEITKKFRDALANEKARILAEKWKVEMEDRKAAKVLEE--RIHEEFKRKEEEERKRGEEQIRLQEEQRAKELYWTLKQAQLHCQASEKEEREWEEQLRRSKAADEERSRRAQRARDEYRHHSLRAIQKGTVAGLSSMFR------------------------ELGQSHEQEA-----RLYHHLPDPGLPQPLAL---PVRTWERPLRPVSRDVIVRWFKEEQLPRRAGFERNTKFIAPWFHGIISREDAEALLENMTEGAFLVRVSEKIWGYTLSYRLQKGFKHFLVDASGDFYSFLGVDPNRHATLTDLVDFHKEEIITVSGGELLQEPCGQRDSPPDYHLLFE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QES0-1", "uniprot_id": "A0A8M9QES0_DANRE", "id": "A0A8M9QES0-1", "name": "", "aln": "MMQQILQEMYIEPDLLAELSEEQKQILFYKIRQEQVRRWNERERRDQSSAGK-------KKSNRRGIQWLLGSDGEVWVWVMGDALGDKPFEDIVEELMEERARKQAQREAQELRRVKEAEIEKKFRDAMAKEKARFAAEKWKEETDDRKAAKQEEEEDRIREELKKCEEEERQRGEEEIRQTEEKRAKELYISLKQEE---KRNERDDKEWQEQLRRSKAADEEMKCKARRARDEYKRQSLRAAEKGLVAGLSGLFHKTHLNGSGHNRRHGTAAEHSSPSAEASHSHATSAGQLTSGHYRHRQHHRYSSPVTQSLTECPVWIRPTRPNSRESIIRWFKEEQRPKRAGYERSSNTIAPWFHGIISRQESEALLTNAVEGSFLVRVSERIWGYTLSYRNPSGFKHFLIDASGDHYNFLGVDQNRHATLADLINFHKEEVITTSGGELLQDPCRPRSSAADHGGLFL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:****::***:*:******: **:*****:*:**:***.*** : : : *::. : :*****:*******:**:. ****:*:* ***: **** ***:**:** * ***** ******:*:****: ***** * :****** ** **:**:*: *****:****:** **:****** :*** : : .*.:::**:************ . :*:******:::**** :** ***** :*: * .:.* .* *:: ..*:: .* ** ** **: *:******* *:***:**.:: ***********:.:* ** * .**:*******:********* ******:*****.*.***** ******:**::*****:**.*******:** *.*..*: ** ", "identical_positions": 263, "similar_positions": 93, "identity": "56.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130531-48", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P36372-1", "uniprot_id": "TAP2_RAT", "id": "P36372-1", "name": "Antigen peptide transporter 2", "aln": "MALSHPRPWAS--------LLLVDLALLGLLQSSLGTLLPPGLPGLWLEGTLRLGVLWGLLKVGGLLR------LVGTFLPLLCLTNPLFFSLRALVGSTMSTSVVRVASASWGWLLADYGAVALSLAVWAVLSPAGAQEK----EPGQENNRALMIRLLRLSKPDLPFLIVAFIFLAMAVWWEMFIPHYSGRVIDILGGDFDPDAFASAIFFMCLFSVGSSLSAGCRGGSFLFAESRINLRIREQLFSSLLRQDLAFFQETKTGELNSRLSSDTSLMSQWLSLNANILLRSLVKVVGLYYFMLQVSPRLTFLSLLDLPLTIAAEKVYNPRHQAVLKEIQDAVAKAGQVVREAVGGLQTVRSFGAEEQEVRRYKEALERCRQLWWRRDLEKSLYLVIQRVMALGMQVLILNVGVQQILAGEVTRGGLLSFLLYQEEVGHHVQNLVYMYGDMLSNVGAAEKVFSYLDRRPNLPNPGTLAPPRLEGRVEFQDVSFSYPSRPEKPVLQGLTFTLHPGKVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGEPLVQYDHHYLHRQVVLVGQEPVLFSGSVKDNIAYGLRDCEDAQVMAAAQAACADDFIGEMTNGINTEIGEKGSQLAVGQKQRLAIARALVRNPRVLILDEATSALDAECEQALQTWR-SQEDRTMLVIAHRLHTVQNADQVLVLKQGQLVE---HDQLRDEQDVYAHLVQQRLEA------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36371-1", "uniprot_id": "TAP2_MOUSE", "id": "P36371-1", "name": "Antigen peptide transporter 2", "aln": "MALSYLRPWVS--------LLLADMALLGLLQGSLGNLLPQGLPGLWIEGTLRLGVLWGLLKVGELLG------LVGTLLPLLCLATPLFFSLRALVGGTASTSVVRVASASWGWLLAGYGAVALSWAVWAVLSPAGVQEK----EPGQEN-RTLMKRLLKLSRPDLPFLIAAFFFLVVAVWGETLIPRYSGRVIDILGGDFDPDAFASAIFFMCLFSVGSSFSAGCRGGSFLFTMSRINLRIREQLFSSLLRQDLGFFQETKTGELNSRLSSDTSLMSRWLPFNANILLRSLVKVVGLYFFMLQVSPRLTFLSLLDLPLTIAAEKVYNPRHQAVLKEIQDAVAKAGQVVREAVGGLQTVRSFGAEEQEVSHYKEALERCRQLWWRRDLEKDVYLVIRRVMALGMQVLILNCGVQQILAGEVTRGGLLSFLLYQEEVGQYVRNLVYMYGDMLSNVGAAEKVFSYLDRKPNLPQPGILAPPWLEGRVEFQDVSFSYPRRPEKPVLQGLTFTLHPGTVTALVGPNGSGKSTVAALLQNLYQPTGGQLLLDGEPLTEYDHHYLHRQVVLVGQEPVLFSGSVKDNIAYGLRDCEDAQVMAAAQAACADDFIGEMTNGINTEIGEKGGQLAVGQKQRLAIARALVRNPRVLILDEATSALDAQCEQALQNWR-SQGDRTMLVIAHRLHTVQNADQVLVLKQGRLVE---HDQLRDGQDVYAHLVQQRLEA------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03519-1", "uniprot_id": "TAP2_HUMAN", "id": "Q03519-1", "name": "Antigen peptide transporter 2", "aln": "MRLPDLRPWTS--------LLLVDAALLWLLQGPLGTLLPQGLPGLWLEGTLRLGGLWGLLKLRGLLG------FVGTLLLPLCLATPLTVSLRALVAGASRAPPARVASAPWSWLLVGYGAAGLSWSLWAVLSPPGAQEK----EQDQVNNKVLMWRLLKLSRPDLPLLVAAFFFLVLAVLGETLIPHYSGRVIDILGGDFDPHAFASAIFFMCLFSFGSSLSAGCRGGCFTYTMSRINLRIREQLFSSLLRQDLGFFQETKTGELNSRLSSDTTLMSNWLPLNANVLLRSLVKVVGLYGFMLSISPRLTLLSLLHMPFTIAAEKVYNTRHQEVLREIQDAVARAGQVVREAVGGLQTVRSFGAEEHEVCRYKEALEQCRQLYWRRDLERALYLLVRRVLHLGVQMLMLSCGLQQMQDGELTQGSLLSFMIYQESVGSYVQTLVYIYGDMLSNVGAAEKVFSYMDRQPNLPSPGTLAPTTLQGVVKFQDVSFAYPNRPDRPVLKGLTFTLRPGEVTALVGPNGSGKSTVAALLQNLYQPTGGQVLLDEKPISQYEHCYLHSQVVSVGQEPVLFSGSVRNNIAYGLQSCEDDKVMAAAQAAHADDFIQEMEHGIYTDVGEKGSQLAAGQKQRLAIARALVRDPRVLILDEATSALDVQCEQALQDWN-SRGDRTVLVIAHRLQTVQRAHQILVLQEGKLQK---LAQL-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F2I0-1", "uniprot_id": "E7F2I0_DANRE", "id": "E7F2I0-1", "name": "Antigen peptide transporter 2", "aln": "MDSDQAHVSVSRVVLVHFCLLFCDLLFWACVWAILLWLDGEGSLDLWCLWALRTITFAGLYLLSTLVPESNLKPLLKRWVALLSFLPPVFDSMQILLDGTLRG-FNPVPDP--GMVILSSATSILIYMVWEMAFPHGGSSKGGRNQKKDEEARALLMRVIRYSRLDYLYLGAAFIFLSLAALFETFIPYCTGKVIDILSGKYQHSNFTWAILLLALCSLGSSMFSGLRGGMFMFSLNRLNKRIRNLLFQNVMKQEIDFFDEIKPGNLASRLISDTDKMGRAVAMNVNVLLRSMVKTCGMLYFMLGVSWQLTLLTCIEMPLLAFLQNSYNSLSQKTSKELQDCNAETGELASSVIGSIKTVRSFKAECQEQQRYEQTINRKLQVLRRKGFYSAVYLLIRRFITVGLKVAMLCQGRNLISSGQLSSGSLLAFVFYQKDMVTSMKHLVYIYGDMLSTVGSSVKVFQLLDRKPQMREAGDLAPEKLKGRITFEKVTFSYLSRPDDTALKSVTLELSPGKLTALVGPSGGGKSSCVSLLQRFYEPKEGEMFLDGEPLYHYQHQYLHKKVAVVSQDPVLFSGSVRYNIEYGLQDCTLERIEEAARKANAHNFICNLEQGYDTDVGECGGQLSAGQKQCIAIARALIRNPQILILDEATSHMDSSTQQAIQDVLNSITDQTVLVIAHRLETIEKADHIIFMEGGEVKEQGTHQQLMDKQGRYHRLREKLFNLETQQAT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : .* **: * : : . * * * .** :** : ** : *: :: : *.: *: *:: *: .: *... . :: . .: * :* : * * ..* : : : :.*: *::: *: * * .**:** :*. * :** :*:*****.*.:: *: **:::.* *.***: :* *** * :: .*:* ***: **..:::*:: **:* *.*:* *** *** *.. :.:*.*:****:**. *: *** :* :**:*: :.:*: :: **. * . :*:**. *.:*::. ..:*.::***** ** :* :*:::::: *: *:.: :**:::*.: :*::: :* * : : *::: *.**:*::**:.: :: ***:******.**:: ***. :**:*:: ..* *** *:* : *:.*:*:* **: ..*:.:*: * ** :******.*.***: .:***.:*:*. *:::** :*: .*:* *** :*. *.*:********: ** ***:.* :: **: * *.:** :: :* *::** *.**:.**** :******:*:*::******** :* . :**:* * *:*:*******.*::.*.:::.:: *.: : ** ", "identical_positions": 256, "similar_positions": 238, "identity": "35.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130531-49", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R5D6-1", "uniprot_id": "RN157_RAT", "id": "M0R5D6-1", "name": "E3 ubiquitin ligase Rnf157", "aln": "MGALTSRQHAGVEEVDIPSNSVYRYPPKSGSYFASHFIMGGEKFDCTHPEGYLFGENSDLNFLGNRPVSFPYAAPPPHEPVKTLRSLINIRKDTLRLVKCAEEVKSHGEEAG--------------------------------------------KAKVHYNVEFTFDTDARVAITIYYQATEEFQNGIASYIPKDNSLQSETVHYKRGVCQQFCLPSHTVDPSEWAEEELGFDLDREVYPLVVHAVVDEGDEYFGHCHVLLGTFEKHS-DGTFCVKPLKQKQVWDGVTYLLQEDYGIENKSNTQDFKVAEDDVRDNSAECVVCLSDVRDTLILPCRHCASCNVHCADTLRYQANNCPICRLPFRALLQIRAMRKKLGPLSPSSFNPIISSQTSDSEEHSSSENIPAGYEVVSLLEALNGP-------------LTSSPAVPPLHVLGDGHLSGMLPSYGSDGHLPPVRTLSPLDHLSDCNSQGLKLNKSLSKSISQNSSVLHEEEDERSCSESDTQLSQR-LSAQHPEEGPDVTPESENLTLSSSG-----------AVDQSSCTGTPLSSTISSPEDPASSSLAQSVMSMAS-----SQIST-----DTVSSMSGSYIAPGTEEEGEAPPSPRAASRAPSE--EEETPAESPDSNFAGLPAGEQDAEGN-------------------DIMEEEDRSPVQED-GQRTCAFLGMECDNNND--FDVASVKALDNKLCSEVCLPG-----TWQHDAAIINRHNTQRRRLSPSSLEDPEEDRP---CVWDPLAV-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TEL6-1", "uniprot_id": "RN157_MOUSE", "id": "Q3TEL6-1", "name": "E3 ubiquitin ligase Rnf157", "aln": "MGALTSRQHAGVEEVDIPSNSVYRYPPKSGSYFASHFIMGGEKFDSTHPEGYLFGENSDLNFLGNRPVAFPYAAPPPQEPVKTLRSLINIRKDTLRLVKCAEEVKSHGEEAG--------------------------------------------KAKVHYNVEFTFDTDARVAITIYYQATEEFQNGIASYIPKDNSLQSETVHYKRGVFQQFCLPSHTVDPSEWAEEELGFDLDREVYPLVVHAVVDEGDEYFGHCHVLLGTFEKHP-DGTFCVKPLKQKQVVDGVSYLLQEIYGIENKYNTQDSKVAEDDVSDNSAECVVCLSDVRDTLILPCRHLCLCNT-CADTLRYQANNCPICRLPFRALLQIRAMRKKLGPLSPSSFNPIISSQTSDSEEHSSSENIPPGYEVVSLLEALNGP-------------LTSSPAVPPLHVLGDGHLSGMLPSYGSDGYLPPVRTLSPLDRLSDCNNQGLKLKKSLSKSISQNSSVLHEEEDERSCSESDTQLSQR-LSVQHPEEGPDVTPESENLTLSSSG-----------AVDQSSCTGTPLSSTISSPEDPASSSLAQSVMSMAS-----SQIST-----DTVSSMSGSYIAPGTEEEGEALPSPRAASRAPSE--GEETPAESPDSNFAGLPAGEQDAEGN-------------------DIIEEEDRSPVRED-GQRTCAFLGMECDNNND--FDVASVKALDNKLCSEVCLPG-----EWQCAEHELGGRRPSARPRSPRGGLG-KEASA---FRIETVALPGTYV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PX1-1", "uniprot_id": "RN157_HUMAN", "id": "Q96PX1-1", "name": "E3 ubiquitin ligase RNF157", "aln": "MGALTSRQHAGVEEVDIPSNSVYRYPPKSGSYFASHFIMGGEKFDSTHPEGYLFGENSDLNFLGNRPVVFPYAAPPPQEPVKTLRSLVNIRKDTLRLVKCAEEVKSPGEEAS--------------------------------------------KAKVHYNVEFTFDTDARVAITIYYQATEEFQNGIASYIPKDNSLQSETVQYKRGVCQQFCLPSHTVDPSEWAEEELGFDLDREVYPLVVHAVVDEGDEYFGHCHVLLGTFEKHT-DGTFCVKPLKQKQVVDGVSYLLQEIYGIENKYNTQDSKVAEDEVSDNSAECVVCLSDVRDTLILPCRHLCLCNT-CADTLRYQANNCPICRLPFRALLQIRAMRKKLGPLSPTSFNPIISSQTSDSEEHPSSENIPPGYEVVSLLEALNGP-------------LTPSPAVPPLHVLGDGHLSGMLPSYGSDGHLPPVRTISPLDRLSDSSSQGLKLKKSLSKSTSQNSSVLHEEEDEHSCSESETQLSQR-PSVQHLGEECGVTPESENLTLSSSG-----------AIDQSSCTGTPLSSTISSPEGPASSSLAQSVMSMAS-----SQIST-----DTVSSMSGSYIAPGTEEEGEALSSPQPASRAPSEE-GEGLPAESPDSNFAGLPAGEQDAEGN-------------------DVIEEEDGSPTQE--GQRTCAFLGMECDNNND--FDIASVKALDNKLCSEVCLPG-----AWQADDNAVS-RNAQRRRLSSSSLED-SETRP---CVWGPLAV-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B321-1", "uniprot_id": "A0A8M2B321_DANRE", "id": "A0A8M2B321-1", "name": "E3 ubiquitin-protein ligase", "aln": "MGALTSRQNAGVEEVDIPSNSVYRYPPKSGSYFASHFIMGGEKFDSTHPEGYLFGENTDLNFLGNRPVVFPYNAPPPHEPVKTLRSLINIRKDTLRLVRCSEDMKLPGQEVG--------------------------------------------KSHSCYNIEFTFDADTQVAITIYYQAIEEFHNGVPIYLPQDSSLQSETVHFKRGVCQQFCLPSHYVNLSEWAEDELLFDMDKDIYPMVVQAVVDEGDEHLGHSHVLLATFEKHM-DGSYCVKPLKQKQVVDGVSYLLQEIYGIENKYNSQESKVAEDEISDNSAECVVCLSDVRDTLILPCRHLCLCNA-CADTLRYQANCCPICRLPFRALLQIRAMRKKLSPLTPTGFNPVITSQTSDSEEHSASEHIPPGYEAVSLLEALNGP-------------LNPSPSAPPLQGLTRGHVSGSVPTFGSESHHTPVRSLSPLDHSVNPN-QTVKHKKSGSKSLSQNSSVLPEEEDEKSCSESEAQTCRRKLHVEQQEVQSGVTPESDNLTLSSSG-----------AIDQS-CNGTPLSSTITSPEDPVSSSLAQSVMSMASSHSQHSQIST-----DTLSSMSGSYMAG---AEGEEAAETPAESRAPSQHEGEDIPNDGKAHNFVAAILEEQDSEGN-------------------DVTEEDCASPTKEHGGRRRSEAPCPEFDNNNQGQSDTHCMTGLDNEQPPDGRFAGLLYLDVYRHGRDPLTHHASTSNINLEEQGVTNEAANPKNKSNRGPLVV-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VY98-1", "uniprot_id": "Q9VY98_DROME", "id": "Q9VY98-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MGNFVSRQNAAVEEADPSTNNAYKYPPRMGNFFGTHFIMGGERFDTPQPESYLFGENADLNFLGNRPTAFPYPPPQANEPTKTLKSLVNIRKESVRFVKTMNDKKLGGVLEKPKMKEIDRDLDLDKEKSNVTIEDVDGNVLCSMGLGGGDADMTPPPPPCSYNIEFTFDSDAKCAITIYYFCSEDVSPSGVTLVPRE-GLTSETYHYEKGINQCFSQPSHVFNPQQMPEDELGYSPGREQYPVAIHCVVEEGSDECRQSHTTICVIDHHPENGSYVLRALKQKIFVDGLCYLLQEIYGIENKAVNKTS--LDEEIDDHGSECVICMSETRDTLILPCRHLCLCNS-CADSLRYQANNCPICRAPFRALLQIRAVQKGIS------THVLHQNTPTSAAGEPAPVDVPPGYIPVSLIEALNGPPQYVARARNSEHDVTDSAATVAASTMTSADIKATSPIKSSSQRRPKIKKN--ASTCTSTSEVGTITNQSGGGNGSSTHSVEIESDPKKSSTATCTSPTLGASTSPEPKQDKLQIVNERKYPRSTAGSGGDGSAGTDDDVDSENEKLSPLLSPGSKSKNVSSKSLKQVVACLEADDDVDNKSSTGDGPTEESSLKKGSSIKRTKPRPELSGSGAPSPAEATAEDSDYYTPEDTQNSILSPLCPTERAKSGDPLGAGSLGNGGLSVGRSAGSVGGQAGVGPVVVGFSSAVKKNLHKKSTSVGNMVGSGSVTTVVDLKSNNVSSLPDMLDSPISGNSASTRSSSDSYSSSSSTKQLLSSNPTTTAANIIVDDKTALQNAVNV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :.***:*.***.* .:*..*:***: *.:*.:*******:** .:**.******:*********. *** .* .:**.***:**:****:::*:*: :: * * . **:*****:*:: ****** . *:. . :*:: .* *** ::::*: * *. *** .: .: .*:** :. .:: **:.::.**:**.: :.*. : .:::* :*:: ::.**** . **: ***** ****** .: :::: *:.:***:*:*:.********** . ** ***:****** ***** **********::* :. : : . .:.: ..:. .:*.** ***:****** :. *.:. . : ..:.. * .*. . ::. . . . ::* . . *.. ** *.: ::*.: : :. . :. : . *::* :*.. . :** *. :..:. *.** * * .: : .: ** : * .** : . . . :.*.:: * : : *: .*: .: : .*. . : . .: . . :* : :.. . . . . ", "identical_positions": 203, "similar_positions": 219, "identity": "25.34%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130531-53", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O76896-1", "uniprot_id": "O76896_DROME", "id": "O76896-1", "name": "", "aln": "MTATLRYRGDKSNLLEFAKNLDAFKKVPEKYTETSEIGGTLSLLSRLLIVYLVYTELHYYWHETDIVYQFEPDIALDEQVQMHVDITVAMPCASLSGVDLMDETQQDVFAYGTLQREGVWWEMSEHDRLQFQAIQIQNHYLREEFHSVADVLFKDIMRDNHPARESASKAPAAPPPGALPLSVDLHGRHNVQPESKFDACRLHGTLGINKVAGVLHLVGGAQPVVGLFEDHWMIELRRMPANFTHRINRLSFGQYSGRIVQPLE-GDEIVIHEEATTVQYFLKVVPTEIHQTFTTIYAFQYAVTENVRKLDSERNSYG--SPGIYFKYDWSALKIIVRNDRDHLVTFAIRLCSIISGIIVISGAINALLLSIRSRLLRTFAPVLYNRLTRAKAAAPDAPSLSSLSAKAGTAPPVNELLHTANLMASVDISAYLPTTPPKLQAGL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ACD6B700-1", "uniprot_id": "A0ACD6B700_DANRE", "id": "A0ACD6B700-1", "name": "Endoplasmic reticulum-Golgi intermediate compartment protein", "aln": "---MRRPSLKNKTPISIIKNLDAFPKVPESYVATSAFGGTVTLTVFILMALLTISEFFVY-QDTWMKYEYEVDRDFTSKLKIKIDITVAMKCERLG-ADVLDIAG-AVVASKEIKYDSVSFDPSAQKKQWYQILQQIQNRLREE-QSLQDVLFKSALKG---------------------YFSDPAPRVDPTPES-QNACRIHGKIYVNKVAGNFHITLGKPIETHKGHAHYASFIKDEVYNFSHRIDHLSFGNDVPGHINPLD-GMEKTTLEQNTLFQYFITVVPTKLHTSNVSVDMHQFSVTERERVVSNEKGNQG--VSGIFFKYKLSPLMVRVSEEHMPLAAFLVRLCGIVGGIFSTS--------DLLHRLIGSFVDIICFRFR---LANKDREVLNRVSQSE------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04651-1", "uniprot_id": "ERV41_YEAST", "id": "Q04651-1", "name": "ER-derived vesicles protein ERV41", "aln": "--------------MAGLKTFDAFPKTEEQYKKKSTKGGLTSLLTYLFLLFIAWTEFGEY-FGGYIDQQYVVDSQVRDTVQINMDIYVNTKCDWLQ-INVRDQTMDRKLVLEELQLEEMPFFIPYDTKVN-DINEIITPELDEILGEAIPAEFREKLDTR-------------------SFFDESDPNKAHLPEF--NGCHVFGSIPVNRVSGELQITAKSLGYVASRKAP------LEELKFNHVINEFSFGDFYPYIDNPLDNTAQFNQDEPLTTYVYYTSVVPTLFKKLGAEVDTNQYSVN-DYRYLYKDVAAKGDKMPGIFFKYNFEPLSIVVSDVRLSFIQFLVRLVAICSFLVYCAS-------WIFTLLDMALITIMGPKWS--LRYQPDDKTKGILDR--------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.:*** *. *.* .* ** :* ::: :. :*: * : :: * . . :::::** * * * :: * : .. :: : : : . . : : : * * . . *:. : : . ** :.*::.*.: :*:*:* :::. . . :*.* *:.:***: :**: : * * *: .**** :: . : *::*. * : .: * .**:***. ..* : * : : : * :** .* . :. : : * :: :: : * . :. ", "identical_positions": 62, "similar_positions": 107, "identity": "13.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130531-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q499S9-1", "uniprot_id": "RHDF1_RAT", "id": "Q499S9-1", "name": "Inactive rhomboid protein 1", "aln": "--------------MSEARRDS-TSSLQ------RKKPPWLKLDIPAVVPPAAEEPSFLQPLRR-QAFLRSVSMPAETARVPSPHHEP---RRLALQRQTSITQTIR--------------------------------------RGTADWFGVSKDSDSTQKWQRKSIRHCSQRYGKLKP----------------------------------------------------------------QVIRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQKIIDPLARGRAFRMADDTADGLSAPHTPVTPGAAS---------------------------LCSFSSSRSGFNR----------------------------------------------------------------LPRRRKRESVAKMSFRAAAALVKGRSIRDG-------------------------------------------------------------------------------------------------------------------------------------------------TLRRGQRRSFTPASFLEEDMVD--------------------------------FPDELDTSFFAREGVLHEELSTYPDEVFESPSEAALKDWEK--APDQADLTGGALDRSELERSHLMLP-----------------LERGWRKQKEGGTLAPQPKVRLRQEVVSAAGPRRGQRIAVPVRKLFAREKRPYG----------------LGMVGRLTNRTYRKRIDSYVKRQIEDMDDHRPFFTYWLTFVHSLVTILAVCIYGIAPVGFSQHETVDSVLRKRGVYENVKYVQQENFWIGPSSEALIHLGAKFSPCMRQDPQVHNFILAAREREKHSACCVRNDRSGCVQTSKEECSS-------TLAVWVKWPVHPSAPDLAGNKRQFGSVCHQDPRVCDEPSSEDPHEWPEDITKWPICTKNSAGNHTN------HPHMDCVITGRPCCIGTKGRCEITSREYCDFMKGYFHEEATLCSQVHCMDDVCGLLPFLNPEVPDQFYRLWLSLFLHAGILHCLVSVCFQMTVLRDLEKLAGWHRIAIIYLLSGVTGNLASAIFLPYRAEVGPAGSQFGILACLFVELFQS-WQILARPWRAFFKLLAVVLFLFAFGLLPWIDNFAHISG-FVSGLFLSFAFLPYISFGKFDLYRKRCQIIIFQAVFLGLLAGLVVLFYFYPVRCEWCEFLTCIPFTDKFCEKYELDAQLH------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PIX5-1", "uniprot_id": "RHDF1_MOUSE", "id": "Q6PIX5-1", "name": "Inactive rhomboid protein 1", "aln": "--------------MSEARRDS-TSSLQ------RKKPPWLKLDIPAAVPPAAEEPSFLQPLRR-QAFLRSVSMPAETARVPSPHHEP---RRLVLQRQTSITQTIR--------------------------------------RGTADWFGVSKDSDSTQKWQRKSIRHCSQRYGKLKP----------------------------------------------------------------QVIRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQKIIDPLARGRAFRMADDTADGLSAPHTPVTPGAAS---------------------------LCSFSSSRSGFNR----------------------------------------------------------------LPRRRKRESVAKMSFRAAAALVKGRSIRDG-------------------------------------------------------------------------------------------------------------------------------------------------TLRRGQRRSFTPASFLEEDMVD--------------------------------FPDELDTSFFAREGVLHEEMSTYPDEVFESPSEAALKDWEK--APDQADLTGGALDRSELERSHLMLP-----------------LERGWRKQKEGGPLAPQPKVRLRQEVVSAAGPRRGQRIAVPVRKLFAREKRPYG----------------LGMVGRLTNRTYRKRIDSYVKRQIEDMDDHRPFFTYWLTFVHSLVTILAVCIYGIAPVGFSQHETVDSVLRKRGVYENVKYVQQENFWIGPSSEALIHLGAKFSPCMRQDPQVHSFILAAREREKHSACCVRNDRSGCVQTSKEECSS-------TLAVWVKWPVHPSAPDLAGNKRQFGSVCHQDPRVCDEPSSEDPHEWPEDITKWPICTKSSAGNHTN------HPHMDCVITGRPCCIGTKGRCEITSREYCDFMRGYFHEEATLCSQVHCMDDVCGLLPFLNPEVPDQFYRLWLSLFLHAGILHCLVSVCFQMTVLRDLEKLAGWHRIAIIYLLSGITGNLASAIFLPYRAEVGPAGSQFGILACLFVELFQS-WQILARPWRAFFKLLAVVLFLFAFGLLPWIDNFAHISG-FVSGLFLSFAFLPYISFGKFDLYRKRCQIIIFQVVFLGLLAGLVVLFYFYPVRCEWCEFLTCIPFTDKFCEKYELDAQLH------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96CC6-1", "uniprot_id": "RHDF1_HUMAN", "id": "Q96CC6-1", "name": "Inactive rhomboid protein 1", "aln": "--------------MSEARRDS-TSSLQ------RKKPPWLKLDIPSAVPLTAEEPSFLQPLRR-QAFLRSVSMPAETAHISSPHHEL---RRPVLQRQTSITQTIR--------------------------------------RGTADWFGVSKDSDSTQKWQRKSIRHCSQRYGKLKP----------------------------------------------------------------QVLRELDLPSQDNVSLTSTETPPPLYVGPCQLGMQKIIDPLARGRAFRVADDTAEGLSAPHTPVTPGAAS---------------------------LCSFSSSRSGFHR----------------------------------------------------------------LPRRRKRESVAKMSFRAAAALMKGRSVRDG-------------------------------------------------------------------------------------------------------------------------------------------------TFRRAQRRSFTPASFLEEDTTD--------------------------------FPDELDTSFFAREGILHEELSTYPDEVFESPSEAALKDWEK--APEQADLTGGALDRSELERSHLMLP-----------------LERGWRKQKEG-AAAPQPKVRLRQEVVSTAGPRRGQRIAVPVRKLFAREKRPYG----------------LGMVGRLTNRTYRKRIDSFVKRQIEDMDDHRPFFTYWLTFVHSLVTILAVCIYGIAPVGFSQHETVDSVLRNRGVYENVKYVQQENFWIGPSSEALIHLGAKFSPCMRQDPQVHSFIRSAREREKHSACCVRNDRSGCVQTSEEECSS-------TLAVWVKWPIHPSAPELAGHKRQFGSVCHQDPRVCDEPSSEDPHEWPEDITKWPICTKNSAGNHTN------HPHMDCVITGRPCCIGTKGRCEITSREYCDFMRGYFHEEATLCSQVHCMDDVCGLLPFLNPEVPDQFYRLWLSLFLHAGILHCLVSICFQMTVLRDLEKLAGWHRIAIIYLLSGVTGNLASAIFLPYRAEVGPAGSQFGILACLFVELFQS-WQILARPWRAFFKLLAVVLFLFTFGLLPWIDNFAHISG-FISGLFLSFAFLPYISFGKFDLYRKRCQIIIFQVVFLGLLAGLVVLFYVYPVRCEWCEFLTCIPFTDKFCEKYELDAQLH------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QMW9-1", "uniprot_id": "A0A8M9QMW9_DANRE", "id": "A0A8M9QMW9-1", "name": "Inactive rhomboid protein", "aln": "--------------MADAEDESRNDSLQ------RKKPPWLRLDIP----TVEEHNHFLQPVMRNSLYLRSASVPTENIQLRCPPVDINGCRRPSVLRKPSISQTIKSPTGKRVRFEQMSTVLVKGHCVSRLEADRRQSLPQIVLRGTADWFGVSNDLDATQKWQRKSLRHCTQRYGKLKP----------------------------------------------------------------QVIREMDLPSQDNLSMTSTETPPPLYVPPPHHGMQRIVDPLARGRAFRNVDE-VDGVNVPQTPITPCAAS---------------------------LCSFTSSRSGFNR----------------------------------------------------------------PPRRRKRESVAKMGFRAAAALVKGRSLRDG-------------------------------------------------------------------------------------------------------------------------------------------------AVRRLPRRSFAAASFLDEDTVD--------------------------------FPDELDTSFFAKDGVTHEELSTYTDEVFESPSEAAIKETDASRAGDERDLTGSALEKTELERSHLMLP-----------------LERGWRKAKDG--ALVQPKVRLRQEVVSVTGQRRGQRITVPVKKLFAKEKRPYG----------------LGMVGKLTNRTYRKRIDSYVKKQIEDMNDHRPFFTYWITFVHLLITVLAVSIYGIAPVGFSQHETVDSVLRNKGVYENVRFMQQENFWVGPSSEALIHLGAKFSPCMRQDEEVHQLIQQKKASEKHSACCVRNDQSGCVQTSQEECSS-------TLALWVKWPQHPSAPVLGDKVRQYGSVCHQDPRICLEPASVSPHVWPDDISKWPICTRYSTGNHTN------LPHIDCVITGRPCCIGTKGRCEITSREYCDFMKGYFHEEATLCSQVHCMDDVCGLLPFLNPEIPDQFYRLWLSLFLHAGILHCLVSVCFQMTILRDLEKLAGWLRISIIYILSGITGNLASAIFLPYRAEVGPAGSQFGILACLFVELFQS-WQILARPWRAFTKLSCVVLFLFAFGLLPWIDNFAHICG-FVSGFFLSFAFLPYISFGRMDMYRKRLQILVALTLFVGIFSSFVVLFYVYPVKCEWCEFLTCIPLTDKFCEKYDLNAHLH------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q76NQ1-1", "uniprot_id": "RHDF1_DROME", "id": "Q76NQ1-1", "name": "Inactive rhomboid protein 1", "aln": "MSSNGSDLGHNNRRNEKGNPDSVHSSMRGSMSSTRRKSINFQNQLQLALESNECDVMYCSLSSGRFRAPNGENFPPHGGKLKLSPLEKYDDANRGVPPPSPAPNSDCFATCVANQLPSQSCSVGSAKPETSVMQKHGMAGNGMVGSGMSGNGMAANGTNYHQRGVSPNSRYRLERYRESQSTPQSKLMDNMGGMPSAVPSVSATRLLLPSNVPLPLAQCENYNAYLGSTVHTPVKRYVPTPPPAMELYSDLSISSSPAANLPTPAAAVASSASTSASAMQSQYANMPYNYRSKCCHSEASHGSLSRTSQTYASCSPACTSPSPAPSTSMSMVFSAASSCSPIMTATSSARSGNHRGDDSDSVIVVPPGGGAMAQIEAENPSGTCLHCNTVRRTTGVHQTTQTTGPISPVPISLPVPMAMPVMSGLNEQMPSQSLESSMVSVQAKRLEGGGNMAVPPGSNQHQLYRSQMASNPRLQHIHHQTQQHQSLQVLPQPQNHHLSCKKRIGMYMRRTTSQFFGVEPSTEAADCALWQGRHRRLAIRCFGMFDTELEYHMQQAIGGGNEDAGQSNGTNGNYAPDRPDILPVQDAIGMDMTMSGDSRRQKCYTNRDFLAGEFVERKASVGYMFVAMVSYLVHMFNKRRPIQMHRVRCPWQWSRSFAPIHVQSHSNQQTDADGCLTDGLEAIIDDEVFFDSPCEITTSAVNDESSDIGRQAAKPRPCADQSGVGVSVYMAERQQNGWRTSALNSGGNATSDINLTGDQSSHQPGAAHIPLCSSVSSQMQPAMRSSHSTTSTCNRGNRITAQLLDGVLENSRRPPLRCIKYFSVNDLDDRTDHRPFFTYWINTVQVVVLILSIICYGIAPIGIGSEQKTGQVLVTSLSLQTVQHVEQRNLWIGPRNIDLVHMGAKFAACMRRDIKITEVVTKTRRHERETACCIRNDDSGCVQSSQAECSIRGLYPTKSISTWKKWSPSESGP----GGRISGSVCGLDPKFCDAPASIAPYEWPDDITKWPICRKTNSFTQRYRYKDHTSEHMVCEVIGHPCCTGLYGECRITTREYCDFIKGYFHEEASLCSQISCLNNVCGMFPFISVETPDQLYRLLTSLCMHAGILHLAITLIFQHLFLADLERLIGTVRTAIVYIMSGFAGNLTSAILVPHRPEVGPSASLSGVVASLIALLVWMHWKYLHKPHIALFKLLLLCSVLVGIGTLPYQLNFLGLLAGVICGCLLTMSLVPFTTFSKYGRKKKINLIWTCVLFHVVVYTAMIVTFYIHPSEFHSISFVDMFSNSNGYDNFTNADHHGVDVVSSNTRYSQTQNSQYYYHHHSDDIIRKSVTFTEKALVSHILYPTAPRKTSAQQWQEVEYSRSFNHLSNYSDRIKKSIGNISKLKQVFTSPIRFSNKNNHSNLMTELTSVHSENKQKYLGYINNNTEFNVL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... :* .*:: *:*. :: :: . : . .. ..*.. :: . : . : .. .:: * :. .::. : *: . *: :** : :. :: ::.:.*. .:.:. :. . . . .** :. . : .. .. . .:*. * :.* : : :*:*** :* .*.:.. .:.:: . ::.: :..* : ::.:: .** : .: * : . ** . . *.: .* .* : . ** :.: : : :. : ::: *. :.***. . ..:.* : * : .* . : *. *. * . :.*. : *. : .:::* *********:. *: :: :*:: *****:*:...:....** . :.*:.::*.*:*:** . *:*:****:.***:* :: ..: : *:.:***:*** *****:*: *** ::: * **. *.* * **** **:.* *:* *: **:**:***** : .: .: *: * : *:*** * *.*.**:******::*******:****: *:::***::**:. * ***:*** ** :****** ::: ** .* ***:* * * :*:*::**.:***:***::*:*.****:.* *::*.*:. *. *: * :* *: ** : .*. :* **: ** : . .:.* :*:::::*: :*.: . :* * ..: : :.::* **.:* . . .*: :. :: : : : : : ", "identical_positions": 224, "similar_positions": 314, "identity": "15.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130531-68", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6NE02-1", "uniprot_id": "BTBDH_HUMAN", "id": "A6NE02-1", "name": "BTB/POZ domain-containing protein 17", "aln": "MPRRGYSKPGSWGSFWAMLTLVGLVT--HAAQRADVGGEAAGTSINHSQAVLQRLQELLRQGNASDVVLRVQAAGTDEVRVFHAHRLLLGLHSELFLELLS--NQSEAVLQEPQDCAAVFDKFIRYLYCGELTVLLTQAIPLHRLATKYGVSSLQRGVADYMRAHLAGG--AGPAVGWYHYAVGTGDEALRESCLQFLAWNLSAVAASTEWGAVSPELLWQLLQRSDLVLQDELELFHALEAWLGRARPPPAVAERALRAIRYPMIPPAQLFQLQARSAALARHGPAVADLLLQAYQFHAASPLHYAKFFDVNGSAFLPRNYLAPAWGAPWVINNPARDDRSTSFQTQLGPSGHDAGRRVTWNVLFSPRWLPVSLRPVYADAAGTALPAARPEDG----RPRLVVTPASSGGDAAGVSFQKTVLVGARQQGRLLVRHAYSFHQSSEEAGDFLAHADLQRRNSEYLVENALHLHLIVKPVYHTLIRTPK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DB72-1", "uniprot_id": "BTBDH_MOUSE", "id": "Q9DB72-1", "name": "BTB/POZ domain-containing protein 17", "aln": "MLRKGSCKPGSWGSFWAILALVGLVT--RAAQRADVGGEAAGTAINHSHMLLQRLQDLLRQGNASDVILRVQAVGTDEVRAFHTHRLLLGLHSELFRELLS--NQSEVMLRESRDCAAVFDKFIRYLYCGELTVLLAQAIPLHRLATKYRVASLQRGVADYMRAHLAGG--VGPAVGWYHYAVSTGDEALRESCLQFLAWNLSAVAGSAEWGAVSPELLAQLLQRSDLVLQDELELFHALEAWLGRARPPPTVAERALRAIRYPMIPPAQLFQLQARSAALARHGPAVADLLLQAYQFHAASPLHYAKFFHVNGSAFLPRNYLAPAWGAPWVINNPARDDRSTSFQTQLGPSGHDAGRRITWNVLFSPRWLPVSLRPVYADAAGTALPAARPEDG----RPRLVVTPASSGGDAAGVSFQKTVLVGARHQGRLLVRHAYSFHQSSEEAGDFLAHADLQRRNSEYLVENALHLHLIVKPVYHTLIRTPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B7K2-1", "uniprot_id": "A0ACD6B7K2_DANRE", "id": "A0ACD6B7K2-1", "name": "", "aln": "MARVRRNELVFVYLFFSMLVAGSLLRPVRGGLRAEGLVEGSAEVISHSQGLVARLEGLLLLGNNSDISLRVETVDADEVKVIQAHTLVLSMQSRVFEEMLRKRNSSTLVLQETAECTAVFDKFIRYLYCGELSLQLDQATPLHSLATKYAISGLQQGLTQYMSQNLASDSPTGHVVGWYQYATKVGDMTLKNNCLQFLSWNLSSVLQSPEWPLVSIELLMTLLQRSDLVLKNELELFEAVETWLTQNNPDSLTAENALRLVRYAMIPPRELFRLQRQSPIMTRYHESVRDLLYMSYQFHSASPLQLAKFFDMNCSLFVPRNYLSSMWGAQWIINNPARDDRSTSFQTQLGPSGFDSSKRVTWNALFSPRWLPLSMRPMYTEQG--AMQPPRPDGGSGIARPRIIITPATSSADFAGVNFQKTVLVLTRQKGKLVVRHILGFHQSTEEVGDFLADADLQLRTSEYVVDGSLYLHIIVKPIYQTLITTKK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * : *:::*. .*: :.. **: *.:. *.**: :: **: ** ** **: ***::..:***:.:::* *:*.::*.:* *:* *.* :*:*. :*:***************:: * ** *** ***** ::.**:*:::** :**.. .* .****:**. .** :*::.*****:****:* *.** ** *** *********::*****.*:*:** : .* . .**.*** :**.**** :**:** :*. ::*: :* *** :****:****: ****.:* * *:*****:. *** *:*********************.*:.:*:***.********:*:**:*:: . *: ..**:.* ***:::***:*..* ***.******* :*::*:*:*** .****:**.*****.**** *.***:*:.:*:**:****:*:*** * .", "identical_positions": 260, "similar_positions": 139, "identity": "53.28%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130531-70", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6TL19-1", "uniprot_id": "GUC2G_MOUSE", "id": "Q6TL19-1", "name": "Guanylate cyclase 2G", "aln": "MASRTRSESPLEPRLYAGAGSRADHPSLVLMLSVVMLVTCLEAAKLTVGFHAPWNISHPFSVQRLGAGLQTVVDKLNSEPVGLGNVSWEFTYTNSTCSAKESLAVFIDQVQKEHISALFGPACPEAAEVIGLLASEWNIPLFDFVGQMAALKDHFWCDTCVTLVPPKQEISAVLRESLRYLGWEHIGVFGGSSADSSWEQVDEMWGAVEDGLQFHFNITASMRYNSSSSDLLQEGLRNMSYVARVIILICSSEDARRILQAAVDLGLDTGEFVFILLQQLEDS-----FWKEVLTKDKVIRFPKVYESVFLIAPSAYGGGIGDDGFRKQVSQELRRPPFQSSITSEDQVSPYSAYLHDALLLYAQTVEEMRKAEKDFRDGRQLISTLRAG-QVTLQGITGPVLLDSQGKRHVDYSVYALQESGNRSLFLPFLHYDSFQKVIRPWRNDSNTSWPHGSLPEYKPGCGFHNDLCKTKPPTVAGMTVTVTAVIPTVTFLVLASAAAITGLMLWRLRGKVQSHPGDT-WWQIRYDSITLLPQHKLSHRGTPVSRRNVSDTSTVKASADCGSLVKRHQDEELFFAPVGLYQGNQVALCYIGDEAEAWVKKPTVRREVCLMCELKHENIVPFFGVCTEPPNICIVTQYCKKGSLQDVMRNSDHEIDWIFKLSFAYDIVNGLLFLHGSPLRSHGNLKPSNCLVDSHMQLKLSGFGLWEFKHGSTWRSYNQEATDHSELYWTAPELLRLRESPCSGTPQGDVYSFAILLRDLIHQQAHGPFEDLEAAPEEIISRIKDPRAPVPLRPSLLEDKGDGRIVALVRECWDESPELRPIFPSIKKTLREASPRGHVSILDSMMGKLETYANHLEEVVEERTRELVAEKRKVEKLLSTMLPSFVGEQLIAGKSVEPEHFESVTIFFSDIVGFTKLCSLSSPLQVVKLLNDLYSLFDHTIQSHDVYKVETIGDAYMVASGLPIRNGAQHADEIATMALHLLSVTTHFQIGHMPEERLKLRIGLHTGPVVAGVVGITMPRYCLFGDTVNMASRMESSSLPLRIHVSQSTAGALLAAGGYHLQKRGTISVKGKGEQTTFWLKGKDGFPVPLP------------------------------------EFTEEEAKVSEIL-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FDF3-1", "uniprot_id": "E7FDF3_DANRE", "id": "E7FDF3-1", "name": "Guanylate cyclase", "aln": "MSGGLASDTSRPIRWWL----------LFTAFTNSVICNKDGQFKLTVGLQAPRNISYPFSLLRLGSAMQIAMDKINSNPALSGNFTFDFVYMDTDCNAKTSLRGFIEQVMEQNVSALFGPPCPEEAEVTGLIASTWNIPMFGFVGQTPKMDNIQVYDTYIKIVPPLKRVGEILLKALEFFGWKHVGMIGGGADANTWDSVEALWKSVDQQLRSKVTVTMGIKFDTSDLEQAKRNLQIISKVARVVVVLANAEDSTAMMIEAQKLGLMSGEYVFLLVQQFEVSGKVDNLWKTSVSETNRT-MLKAFDMVFVLAEKSYDG-YDYYDFFDQAYDKLKGDPFYSNLSSVKEVSSYAAYLHDAVLLYAMGLKEAFKSGKDIRHGREIVQKLRDRTSIRFYGASGLVHFDEYGERNLDYSVYDLQQTETLIQFVSVLDFDSHTKMIKPTLRFSNIVWQNGKPPTDNPSCGFDNELCEWLDNEIS-----LLVLLVALPLIGVAAVSLITLLTLQKLR--LQSRLDESNWWLINYSDITILREPK----GTQILSVNTTPSKCGSGGSQSMLSSNSCNTREAIYATVGLFQGNEVGIKYLKNQIIPDIKKPSIIAEFNMLKEMKHENLVQFFGVCIDPPNVCIVMQYCKKGSLKDVLGNHEIDLDWMFKLSFAYDIVNGMEYIHKSSLKSHGNLRPSTCLVDSRLQIKLSGFGLWEFKCGTKHRLIPLDSPKYEEMYWTAPEFLREIFYPFNGTQKGDVYSFAIIIRELIYSTEVGPYHDVHLEPKEIIKQLRTPMSEEPLRPTLSADICDERLIPLIKACWSENPDHRPPFGSIRRQLRDACPESHANILDNMVNKLEKYANHLEEVVEERTSQLTVEKSRADKLLSSMLPRYIADQLMAGKSVEPRSYEMVTIFFSDIVGFTTMCSVSSALEVVTLLNDLYSLFDDIIKLYDVYKVETIGDAYMVASGLPISNGTLHAEEISTMALHFLSSIKRFKIRHLPNERLALRIGINSGPVVAGVVGSTMPRYCLFGDTVNTASRMESNSLPLKIHISQSTADILLTIGTFELEERGDIEIKGKGTQKTFWLLSKPGFTFPPTGQDSNPSPKSGTDSCHIKQEKTKAANDGDFKERRTIQRTSAMTKMTDMYTLTVPDV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:. *::. * : *. :: :: . *****::** ***:***: ***:.:* .:**:**:*. **.:::*.* :: *.** ** **:** ::::******.*** *** **:** ****:*.**** . :.: ** :.:*** :.:. :* ::*.::**:*:*::**.: .:*:.*: :* :*:: *: :..:* .:::::*. : :..*: :* ****::::..:**: :: * .*** :**:**:*:**:* * :** ::: : : *.:: **::* .:*.* . .* .*. ::*: ** *.::* .:**.*:******:**** ::* *: **:*.**:::..** .: : * :* * :*. *:*::***** **:: . *:..*.:**. *:*:* . ** * :*. * :*.***.*:**: :: : .:: ::.:: :*:.: ** * * :** :**: .:: ** *.*..**:* : * ** : *.: :. ...::. : : .* ::*.***:***:*.: *: :: . :***:: *. :: *:****:* ***** :***:*** ********:**: * : ::**:************: ::* *.*:*****:**.*****::*:*********** *:. * ::..:.*:******:** * .** :********::*:**:. **:.*:. *:***.::: * : ****:* * * *::.*:: **.*.*: ** * **:: **:*.*..*..***.*:.***.************* :*..** :.:****:*** ::.:**:*******. :* ************.:**:**.*:**.**********. *: :******************** **: **:**:*****:** .:*:* *:*:*** ****:::********* ************* ******.****:**:*****. **: * :.*::** *.:**** *.**** .* **..* . : *. :*:::: ", "identical_positions": 508, "similar_positions": 357, "identity": "44.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130531-80", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AKZ1-1", "uniprot_id": "A0A8I6AKZ1_RAT", "id": "A0A8I6AKZ1-1", "name": "", "aln": "MWGGTCCRSSTRTSAEHPSPGSRLQLPACPTPGTRPLRAEGRMQTPRPAMRMEAGEAAPPVG-----------------AGGRSGGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRLCQGE-ELQSDRDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIKDRMEEKDYTVT-QVPPKHVYRVLQCQEEELTQMVSTMSDGWRFEQL----------------VNIGSSYN-YGSEDQAEFLCVVSKELHSSPHGLSSESTRKTKSTDEQLEEQRRQE--VEEVEVAQVQVEADAQEKALSSQDPANLFSLPPPPPPPPLPAGGPASSSSTSSSSWISSAPCLFPLCPCPGFLSACSRLHPGATLVPVSRALSPGPLALHPQASCLPPPSPLPAPPASWPGEEGRGRICSMSSNPAEHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E0CYQ0-1", "uniprot_id": "E0CYQ0_MOUSE", "id": "E0CYQ0-1", "name": "", "aln": "-------------------------------------------------MRMEAGEAAPPVG-----------------AGGRPGGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRLCQGE-ELQSDRDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIKDRMEEKDYTVA-QVPPKHVYRVLQCQEEELTQMVSTMSDGWRFEQL----------------VNIGSSYN-YGSEDQAEFLCVVSKELHSSPHGLSSESTRKAKSTDEQLEEQRRQE--VEEVEVAQVQVEADAQEKAITSQR-------------------HPDVSPQITSRDLGFRSEILY-FCTTG--------WAPGP-----RRKTSP-----LPCQCCLHLPG-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N5Z5-1", "uniprot_id": "KCD17_HUMAN", "id": "Q8N5Z5-1", "name": "BTB/POZ domain-containing protein KCTD17", "aln": "-------------------------------------------------MRMEAGEAAPPAG-----------------AGGRAAGGWGKWVRLNVGGTVFLTTRQTLCREQKSFLSRLCQGE-ELQSDRDETGAYLIDRDPTYFGPILNFLRHGKLVLDKDMAEEGVLEEAEFYNIGPLIRIIKDRMEEKDYTVT-QVPPKHVYRVLQCQEEELTQMVSTMSDGWRFEQL----------------VNIGSSYN-YGSEDQAEFLCVVSKELHSTPNGLSSESSRKTKSTEEQLEEQQQQEEEVEEVEVEQVQVEADAQEKAQSSQDPANLFSLPPLP---------PPPLPAGGSRPHPLRPEAELAVRASP---------RPLA------RPQSCHPCCYKPEAPGCEAPDHLQGLGVPI--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9W579-1", "uniprot_id": "Q9W579_DROME", "id": "Q9W579-1", "name": "", "aln": "-----------------------------------MSTVFINSRKSPNVLKKQGTD---------------------------------QWVKLNVGGTYFLTTKTTLSRDPNSFLSRLIQEDCDLISDRDETGAYLIDRDPKYFAPVLNYLRHGKLVLD-GVSEEGVLEEAEFYNVTQLIALLKECILHRDQRP--QTDKKRVYRVLQCREQELTQMISTLSDGWRFEQL------------------ISMQYTNYGPFENNEFLCVVSKECGTTAG------------RELELNDRAKVLQ-------QKGSRILG----I------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M2B2U6-1", "uniprot_id": "A0A8M2B2U6_DANRE", "id": "A0A8M2B2U6-1", "name": "", "aln": "--------MATEDKGKTAAPRGLPEIECLSGTITTHSNLNSNNNNNNNNKDNEGSEGATTTTSTDVESTGAENIIGNGSAVNTTGGNNGKWVRLNVGGTVFLTTRQTLLKEQTSFLYRLCQQQ-DLHSDTDETGAYVIDRDPTYFGPILNYLRHGKLVYNKELAEEGVLEEAEFYNITPLIKLIKERILERDSKATQQVPPKHVYRVLQCQEEELTQMVSTMSDGWKFEQVSVRACRKPRPGLLWTMVNIGSSYS-YGTEDQAEFLCVVSKELHTSAGGLGTEQSHKTKTSDTQEEDGAREEEEVEEEEREEGERNSSPNEWIRD----------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : :**:****** ****: ** :: .*** ** * : :* ** ******:*****.**.*:**:******* : ::************: ** ::*: : .:* *. *:*******:*:*****:**:****:***: *. .*. **. :: ********* ::. : : :: : : . . ", "identical_positions": 99, "similar_positions": 51, "identity": "22.35%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130603-100", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2ACJ2-1", "uniprot_id": "FP100_MOUSE", "id": "A2ACJ2-1", "name": "Fanconi anemia core complex-associated protein 100", "aln": "MAGASSRVHYLSDFCCPLGGRAAGKPFVLRHEAEVFLSTGREFVYVYDQEGGLLTAVYQFPDQVWHLQLLAIRRALYVLCARTGIYCLSLDSLDRSGSQACEDK--EEAAPPYPVIHVDPDACVLPDAALCAFTVLDDMLVTLAQGPTQWKMQLFERPCAGEEPLPRGQIGEVELSTCTPPGG-VPEKPAAPRFLPVLCCVFPPDSRAPHGHPQGCGCFTLEEALFGLLFGVDATLLQSPVILCGLPDGQLCCVVLKALVTSGLAPGDPKVLVKILHHLEEPVIFIGALRAEPHEEEAAGELLPGQHEHSDCLVALGHQGRTLAIKAS--WSESGNLVPELREYCLPGPVLCAACDRDGHVYHSTPSDLCVVDLTRRDSPWNPEKPDGAIGGLPSVLCPASLNICSALALCVTARAPTGSTELLALSSKGRLITCSLDLNSEAPVPAKMAMANAGQKIKELLLDIGDVSERVSFLKKAVDQRNKAITSLNEAMNVSCALLSHPEGDRP--------IACTITTSWSRLELRDMLMATCTLENSSSFSLDQGWTLCIQVLTSSSALDLDGTGSAFTYTIPVDRLGPGSRREVTLPLGPSESGVLDLPVTMSCWLFYSLREVVGAALAPSDPLEAPYLEQFP-LSLPKQEGVCLPLCKRTVDMLQCLRFAGAATHPAQAPCMPGPACEPVETFLKTCQAPGSEPTGAASLRAKYLPPSTASIRVSAGLLRAALEDSHSGFHLCSATLRWLLAENAAVDVVRAQTLSSIQGIAPDGTDVNLTVHEVAVTDLSPAGPIQAVEIQVESSSLANMCRAHHAIIRRIQTMVTEQAALGSSPPDLRMQYLQQIHANHQELLREVQALRDQLCTEDELSSCSTAQKLLHIYKQLRNPSLVLL----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q0VG06-1", "uniprot_id": "FP100_HUMAN", "id": "Q0VG06-1", "name": "Fanconi anemia core complex-associated protein 100", "aln": "MAGAAPRVRYLAGFCCPLGGLAAGKPRVLCHEAEVFLSTGSELVYVYDQEGGLLTAAFRFPDQVWHLELLAPRRLLYALCARRGLYCLSLDHPGRSRSTSQDDRDSEDGDQPSPVIPVDPDACILPDAALCAFTLLDSVLVTLVQGPARWKMQLFEQPCPGEDPRPGGQIGEVELSSYTPPAG-VPGKPAAPHFLPVLCSVSPSGSRVPHDLLGGSGGFTLEDALFGLLFGADATLLQSPVVLCGLPDGQLCCVILKALVTSRSAPGDPNALVKILHHLEEPVIFIGALKTEPQAAEAAENFLPDEDVHCDCLVAFGHHGRMLAIKAS--WDESGKLVPELREYCLPGPVLCAACGGGGRVYHSTPSDLCVVDLSRGSTPLGPEQPEEGPGGLPPMLCPASLNICSVVSLSASPRTHEGGTKLLALSAKGRLMTCSLDLDSEMPGPARMTTESAGQKIKELLSGIGNISERVSFLKKAVDQRNKALTSLNEAMNVSCALLSSGTGPRP--------ISCTTSTTWSRLQTQDVLMATCVLENSSSFSLDQGWTLCIQVLTSSCALDLDSACSAITYTIPVDQLGPGARREVTLPLGPGENGGLDLPVTVSCTLFYSLREVVGGALAPSD-SEDPFLDECPSDVLPEQEGVCLPLSRHTVDMLQCLRFPGLAPPHTRAPSPLGPTRDPVATFLETCREPGSQPAGPASLRAEYLPPSVASIKVSAELLRAALKDGHSGVPLCCATLQWLLAENAAVDVVRARALSSIQGVAPDGANVHLIVREVAMTDLCPAGPIQAVEIQVESSSLADICRAHHAVVGRMQTMVTEQATQGSSAPDLRVQYLRQIHANHETLLREVQTLRDRLCTEDEASSCATAQRLLQVYRQLRHPSLILL----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U1W0-1", "uniprot_id": "A0AB32U1W0_DANRE", "id": "A0AB32U1W0-1", "name": "", "aln": "MAAARCSVEFLSEFSDCQ----SDSVRFIREDTNLFLTSGHRDVLIFSVQDRKVKTVIQFEDSVTFLDLSDDKHRLYALCKNGGLYCIPLPQQLSSSPVN--------KSPEPMLHVVSDDSLVLKNAGLQAFTIVKKILVTLSLDKSVWSFNLYEEPGS----KPFCKLAHIQITTVTTCCLNVADKETSVSSPPVLTCIHPEGSTSVKTHQS-DLHPHLEPHLFRLLFGVDAALVSSPVILCGLPDGRICCFPLLVPTLTGPR-GEQRSPIRVLQSLEQPIVFIGTCISGEHGPQS--------------LIVVGQRGKLLMVRSKPRSSEGKEADYSFNEHSVRGPVLCACVD-DKRLFYSSLNDFHALQLTTSSS-----SEAMGTEPQLQALISNSLGVCRVIALAGPYTNPTGSVQLLALSSSGRLMRVNLPQGSEKGILSRLSSSLAGQRVKDLLASIGNVWERAESLKQKLQEKNESLKQLNQVLNICSLLLESNGKEKQSNMDTKPLISCHGAARWSSLLQKTSLTLTCVLENSSGCTLEHGWTLCFQVHSFYQHPNTESASS--SYSFPLRKLDSGQKLDVTIPLES--NGGLFLPVKVCCSLSFSLCALFGPEASSPG----------VFQLLKEAGSISATLNTLTVDWLDALRLEGSFSPNDIR---CNTVSEGIQAFLRSRGVSTKHLDNISNP-----GPVAVVVSVSIELLKSKLHLSTTSSLESSMSVLNWLVSPEKIGSVKSPVVNAYS---PDGCSVKIMAKEVTLGDFYSEGPLEALEIRVESSSVAAVCGLHHAILRRLLDLLRDSSAQYSHTRNLKAQSLCEAVRHVEVIYLFTLQLFN--CMNKVLRCHHMNHYSVKVSEHFNSSPEFNMRQAMVTHKQC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.* *.:*: *. :.. .: .::::**::* . * ::. :. :.:. :* *.* .*:* :: **.** . *:**:.* * . : *. *: :* :*.* ***::..:**** . : *.::*:*.* . * ::..::::: *. *. * :: *** .: * .* : ** ** ****.**:*:.***:*******::**. * . . : *: . :::*: **:*::***: : : :: *:..*::*: * :::. .*. : .:.*:.: ******. . . ::::*: .*: .::*: .: . . * . **.:* .::*. . *..:*****:.***: .* .** :::: ***::*:** .**:: **.. **: ::::*:::..**:.:*:.. **. : *:* :: ** * : * **.*****. :*::*****:** : : :.: * :*::*: :*..* : :**:** . .* * ***.:.* * :** :.* :... * : .:. .* *** *:.**: * . ... : : :**.: . .. . :. * .. : ** **:: *. . :. .. :: *.. :. *:: .:.: . *** .*:: .:**:: *: . **::*:**:*****:* :* ***:: *: :: :.:: * . :*: * * : : : : . * : * :. . : ::: .::. .. . : ", "identical_positions": 219, "similar_positions": 315, "identity": "24.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130603-101", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K4I3-1", "uniprot_id": "A0A0G2K4I3_RAT", "id": "A0A0G2K4I3-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQWDLKTVLSLPQYPGEFLHP-----------VVYACTAVMLLCLLASVITYILHQSAIRISRKGRHALLNFCFHAALTFTVFAGGINRTKHPILCQAVGIALHYSTLSTMLWIGVTARNIYKQVTKKALPCPG-----ADQP--PYPKQPLLRFYLISGGVPFIICGVTAATNIRNYGTEDEDVAYCWMAWEPSLGAFYGPAAFITLVTCVYFLCTYVQLRRHPERRYELRERTEEQQRLAVPETGHRHGMRP-----GTPPTCDALAASQLQN---------------------------EHSFKAQLRAAAFTLFLFTATWTFGALAVSQGDFLDMIFSCLYGAFCVTLGLFVLIHHCAKREDVWQCWWS-----CCPSRGDTSAT---KPSAHPTLDANGDALGH----TACLQDSPCPGKLRGFGHPPASHCKMTNLHAAQGHVSCLS----------------------------------------------PATPCCAKMHCEQ-LMEEEA-HVHMGEEDAFPHDHH----------------------------LHDPHLHRCLKGRTKPHYFSRHQAAAAEREYAYHIPS-SLDGSPHSSRTESPTSS--------------------------------------------------------------------------------------------LEGPMGVHTLACCAQADPF---------PMVS--QPEGGDTSPGLYG----------------------------------------------------------------------------------CPPR----LSPGPAHLEMLR-RTQSLPFGSP---SQNGLL--QGDVREGLPFGTDGTGNIRTGPWKNETTV-----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C4G9-1", "uniprot_id": "AGRA1_MOUSE", "id": "Q8C4G9-1", "name": "Adhesion G protein-coupled receptor A1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTQWDLKTVLSLPQYPGEFLHP-----------VVYACTAVMLLCLLASVITYILHQSAIRISRKGRHALLNFCFHAALTFTVFAGGINRTQHPILCQAVGIALHYSTLSTMLWIGVTARNIYKQVTKKALPCPG-----ADQP--PYPKQPLLRFYLISGGVPFIICGVTAATNIRNYGTEDEDVAYCWMAWEPSLGAFYGPAAFIALVTCVYFLCTYVQLRRHPERRYELRERTEEQQRLAVPESGHRHGVRP-----GTPPTCDALAASQLQN---------------------------EHSFKAQLRAAAFTLFLFTATWTFGALAVSQGHFLDMIFSCLYGAFCVTLGLFVLIHHCAKREDVWQCWWS-----CCPSRGDTSTT---KPGAHPTLDANGDALGH----TACLQDSPCPGKLRGFGHPPASHCKMTNLQAAQGHVSCLS----------------------------------------------PATPCCAKMHCEQ-LMEEEAAHIHMAEEDVYPHDPH----------------------------LHDPHLHRCLKGRTKSHYFSRHQAAAAEREYAYHIPS-SLDGSPHSSRSESPTSS--------------------------------------------------------------------------------------------LEGPMGMHTLACCAQADPF---------PMVS--QPEGGDTSPGLYG----------------------------------------------------------------------------------CPPH----LSPGPAHLEMLR-RTQSLPFGGP---SQNGLL--QGDVREGLPFGTDGTGNIRTGPWKNETTV-----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86SQ6-3", "uniprot_id": "AGRA1_HUMAN", "id": "Q86SQ6-3", "name": "Adhesion G protein-coupled receptor A1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDLKTVLSLPRYPGEFLHP-----------VVYACTAVMLLCLLASFVTYIVHQSAIRISRKGRHTLLNFCFHAALTFTVFAGGINRTKYPILCQAVGIVLHYSTLSTMLWIGVTARNIYKQVTKKAPLCLD-----TDQP--PYPRQPLLRFYLVSGGVPFIICGVTAATNIRNYGTEDEDTAYCWMAWEPSLGAFYGPAAIITLVTCVYFLGTYVQLRRHPGRRYELRTQPEEQRRLATPEGGR--GIRP-----GTPPAHDAPGASVLQN---------------------------EHSFQAQLRAAAFTLFLFTATWAFGALAVSQGHFLDMVFSCLYGAFCVTLGLFVLIHHCAKREDVWQCWWA-----CCPPRKD----------AHPALDANGAALGR----AACLH-SPGLGQPRGFAHPPG-PCKMTNLQAAQGHASCLS----------------------------------------------PATPCCAKMHCEP-LTADEA-HVHLQEEGAFG---------------------------------HDPHLHGCLQGRTKPPYFSRHPAE--EPEYAYHIPS-SLDGSPRSSRTDSPPSS--------------------------------------------------------------------------------------------LDGPAGTHTLACCTQGDPF---------PMVT--QPEGSDGSPALYS----------------------------------------------------------------------------------CPTQPGREAALGPGHLEMLR-RTQSLPFGGP---SQNGLP--KGKLLEGLPFGTDGTGNIRTGPWKNETTV-----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GY35-1", "uniprot_id": "A0AC58GY35_DANRE", "id": "A0AC58GY35-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRRKHRLEHKEPDLKRVLSFPPYPGDYLHP-----------VVYACTAVMLLCLLISIMTYIVHHSIIRISRKGWHMLLNFLFHTAMTFGVFAGGINQIKYPVICQVVGIILHYSSLSSMLWLLFTARNVCKEVSKAPPIPQD-----RDPPTQPRPKATIFRFYLVSGGVPLIIVGVTAAVNLDNYGSRD-DAPYCWMAWEPSLGGFYGPTAFLVLVMCIYFLCTYVQLKRHPERKYELKAMTEEQQRLAVAEIGHCHAVSGEPGEHGDHTGCTAITASMLAN---------------------------EHSFKAQLRATAFTLFLFLATWVFGALAVSQGHFLDMIFSCLYGAFSVTLGLFLLIQHCAKRDDVWHRWWA-----CCPNKPKVEVNGEAAGNAIPTTQSHSHTPSHGQNQIHCQVDSSCLGKPLLSPHLSP-HCKLGSLPSTQNHTS----------------------------------------------------TCCATLHSPSSLIGSSTRPQSLPDELPRP----------------------------------TLPLQSCLKDRSKTRSFNRPRPC--LRDYSYHMTSTSMDGSVHSSHLDSPHSVH-------------------------------------LDNPLTCHTSHLDTQLSCHSPHPDNQLRCPSPSPHLETLASHGLHDSLSCHSAHLDSQLSCHRHMCCAKADPFSSICCPNADPFVSPCQAEDPDMGSLMYS----------------------------------------------------------------------------------CAKMADK-EDESMLHLDITPPRVSHATLGRKGTLSRRGTLSRNSSQHEDYAITSDSTGNIRTGPWKNETTV-----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KV24-1", "uniprot_id": "Q7KV24_DROME", "id": "Q7KV24-1", "name": "", "aln": "MPTATATSTAAEGGQAVQVQTHQDTELPQNPETGIATGQGTASSCPRKCSCRSTAENIHSLKIRCDEQQITNWRELDFGEDVTSIVSINASKNSIALITAEDFRNFTELKRLDLSFNLLTELDKDTFGDSLAHLEKLKLAGNAISHIYEGTFDQMPKLKLLDLSGNPLACDCGLIWLIAWSSSREVRLQPPPKCESPGNFRGMPLKKLRVGKDFHCETLLQPLLELIPSQNQVAFEGDELQLKCHAPRVAIGVPRESEDLPTKAYVFWGWSEKIRAKNSTEDIIYQDPTKVFGDVNLETRHSTDSGILQSILRIASLTQNHTGMWDCTLRSQQANLSQAIVLHVVAKGTLYCEARVVHTNKGTYHWPRTMRGETVLQECVEEPSDATQARRASHECGPSGEWLNLDTESCVYVSETTRILEQFAKVNLTLTKGQNALEIARRLHNFTQAQTQLNRIRDPMDLEYIARTLVKYLDQLEQPQQQQEISHLLMDIVSQLLNLPAHLFRAAQSEQGTGQRLLHVVESSAMRLALASTQAEPLPAEMIPWRGSLAQQRNLFVEFFNISLDAFVSLSCVWLEQSPRGFQCNSANDTIPMYEHGDIDAAIQLPYSVIGNSSTTLPATTTIRSLRLMISLHRNGKLLPNLRGSHNESLSSAIIGILAYSSDGEALQFRADNELDPEEDVYQQRVTVMLRAHPYHNPLSAPQPAWWDADEQRWETSVCQQHYQHRTLVMFSCSRTGYYGLLQRSQYLNDFRSEESGARFRHPPAAVYAGCGLLFACCAFNAVTFAVFGRAVRINRVQRHALVNTWLALGALALAFSLGIYQTASQPQCRLLGLLMHYLGLCVLLWVCVSLSSMYKRLTKTTTSGQGQCPGQDMEPQRERERKPILGIYLVGWGIALLICGISSAVNLAEYATYD----YCFLHSSTTLNALLVPAVILVIFCGILALCIYYQLSQQAVNVLQLQMQHQQNRQYSDNNTQATEHIDLDWLDANGSATTAAIGGGSGNHGGRKEQDHMQEQYSTLSNPLSSIVDDFERSNLSHLRGHFIFLVLYAGAWLSAAAYVNGG---QELYVLSFAGCCSVLGIFLLIFYNLSRNDARQAWSQGRDGRSIPAKLVTYNNGSQARGAHPSSMMPGPGTAMISNSIVAYKANPGPGSLYEANNSAGSRSNSQCSRSMRSQTRSQTRSQQEQLLQANGAGGVTIINNTSGQPGAGGGPAAGGVSGSTGGAPVPPHSLNALLHGSSHDLIPSAEIFYNPNQINVARKFFKKQKRLAKRNNFELQRQTMPQMQLQMQMQMQLHSQHSLSDASSEQLYSRHHNAMTMLAGGSKINNTNLHYKNQGSPMAGAPKEHGNMGAMSSGGDSMQFKRFVPASASSASKIMQANIYTNIPETLTPQHEVIKLRANGRTRTPSLLDETLHELDDDEEDEEEEEHGQTPATMEEPEHELEEEDASSLDEHAPLYANTLPPASGMSSLFRNRGSSHQPMSSTPVKQPSLEAMNSLGLPEVSLEEPLLQKHEIYVSNSLQVTTSNSIQLDDDFPSVLIRFSQQQQSKSLNNISEMLAGGGGGGGNAPGLDSLGDQQESSQLSVNEGSTLEEQQLRQIYSCSSSNLSQLKGHHPTATVDTEDDGRLLSGSPTNESDLNYQNSEISIRSHGLYAPQADNDLNLTLTDDFRCYQSSNASDADVDVLNEFDDEFVAATGGERVVGDAEQDPHHDHDQDTSIDELYEAIKCRSPLRNKQEAVERFERERERDREKEMEMEAKPLSNSHNENLNETIEDDSSQSSVISYIDPRAANEPRPFPS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :*. . * .:: .*** .::: * . :*: :. :**.* * *:* : . .*: ** : *: :*: :** *. :**: .: .: *.::* . . * : .:: :**:. *:.::* *:::*.*: :*.: * **:: ..:*..: *:.::.:. : * * ** ::. . :*: ::::: : : : . . * .. : *:* ::**. : *.*: .:* .* *. * : :: :.. . .**:*:** : .*:*. : * . * : * *: . . . .. *. : . .: : :.:. . * :* .: :: : .*.. :. :.* . :: . .:. . :.* .. . : . . : *: : : : .. . . .. :*.: . . . .. ::. *.: :*. .**: : ", "identical_positions": 78, "similar_positions": 198, "identity": "4.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130603-102", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6NHT5-1", "uniprot_id": "HMX3_HUMAN", "id": "A6NHT5-1", "name": "Homeobox protein HMX3", "aln": "MPEPGPDAAGTASAQPQPPPPPPPAPKESPFSIKNLLNGDHHRPPPKPQPPPRTLFAPASAAAAAAAAAAAAAKGALEGAAGFALSQVGDLAFPRFEIPAQRFALPAHYLERSPAWWYPYTLTPAGGHLPRPEASEKALLRDSSPASGTDRDSPEPLLKADPDHKELDSKSPDEIILEESDSEESKKEGEAAPGAAGASVGAAAATPGAEDWKKGAESPEKKPACRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLSHAAAQRIVRVPILYHENSAAEGAAAAAAGAPVPVSQPLLTFPHPVYYSHPVVSSVPLLRPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P42581-1", "uniprot_id": "HMX3_MOUSE", "id": "P42581-1", "name": "Homeobox protein HMX3", "aln": "MPEPGPDASGTASAPPPQPPPQPPAPKESPFSIRNLLNGDHHRPPPKPQPPPRTLFAPASAAAAAAAAAAAAAKGALEGAAGFALSQVGDLAFPRFEIPAQRFALPAHYLERSPAWWYPYTLTPAGGHLPRPEASEKALLRDSSPASGTDRDSPEPLLKADPDHKELDSKSPDEIILEESDSEEGKKEGEAVPGAAGTTVGATTATPGSEDWKAGAESPEKKPACRKKKTRTVFSRSQVFQLESTFDMKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLSHAAAQRIVRVPILYHENSAAEG-AAAAAGAPVPVSQPLLTFPHPVYYSHPVVSSVPLLRPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "U3JAS7-1", "uniprot_id": "U3JAS7_DANRE", "id": "U3JAS7-1", "name": "", "aln": "MEEK---------------------LKDSPFSIQNLLS--------RPERPP------------------------------MPVCRVPELGFLR---------LGPWCCAGAP-------ETPAG------------MRRAPADTLQPDCAAPGPSAEDDDD----DEEAP----LEDSDCEEAR--------------------------------AQVKKLCRKKKTRTVFSRAQVFQLESTFDLKRYLSSSERAGLAASLHLTETQVKIWFQNRRNKWKRQIAAELESASLSH--AHRVVRVPVIYHE--------------------------HALYYPH------PLIRPV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * *:*****:***. :*: ** :.:.:* :*.* * * . :* **** : * .: : .* :* * : * * *.::* **:**.**.: .: * ************:**********:*************************************:*****:*.*** *:*:****::*** *.:**.* **:***", "identical_positions": 125, "similar_positions": 43, "identity": "35.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130603-106", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8M9Q4J4-1", "uniprot_id": "A0A8M9Q4J4_DANRE", "id": "A0A8M9Q4J4-1", "name": "", "aln": "-------------------MEVIESIVTEAIEVEDSTTTVTTLETEKSKA---------EFVWTLQATWHLVHVRLDMDTEFDQPVCKKKKLWETVAERVTAKLRADEGTDVSVKAFECDLKWRNMLATYRKNAERAKRLGTNSVHWEFFKEMHEVLGRSYEEVEAQRKAKISASKLGKAIAS---------KRFTPILPTPTTSAP-------QLPNARPPQD-----------LLQLYLELQERK-------------------------------------------------------------------LNMWAQQKALEERKIEAINNLAR-----AITCLSQNNTLQKFESEASQ-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E9A0-1", "uniprot_id": "Q0E9A0_DROME", "id": "Q0E9A0-1", "name": "Myb/SANT-like DNA-binding domain-containing protein", "aln": "MAQVQLNAGNGQAPSNGNNVEDNEPYQISDDDLDDLDDDCLLEEADTSGAGNNVGRGPYERAWTTEATRALIHIRGPMEGSFTEGRQKRTALWLHCTRQLQR-------LGFRYSAAKVQKKWHNILITYNKNLN--KKYVSGYVHWEFFEEMFKYLQGKKADFDMQLPQQTSNAPQAPHSANGQNPNPGIPQQPLQLQPTPVSLKPGTPQMQVQLPPQTAAKDSQPYITPVDQVLLQAQMNLDSKSNDEFDEDSNSMSEVVRQPKMEYDGDQVAEAERTNDSSQHLEVNGKLYDLARPMGSHQASGIPDDIWWKDYFERKLEVEREKIELQRSLQREQVQIQKMSLVQQERIERMKIDAINSLTGTLQKLVEAKCRRA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* *. . :::* *::.* * * .** :** *:*:* *: .* : *:. ** :.:: .. .* : : **:*:* **.** : *: :. ******:**.: * . :.: * : * : . *. :: : ***.: * *** ..:* *** ::*:.:. : : :: :*..*** ..* * .* *:: ::::: :* : ", "identical_positions": 62, "similar_positions": 78, "identity": "16.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130603-12", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VMM8-1", "uniprot_id": "Q9VMM8_DROME", "id": "Q9VMM8-1", "name": "Phospholipase B1, membrane-associated", "aln": "MASITYALCLCSLFILFSPLVSANRRVRRQNRSDRLLADIGVRAQSYDPRVPENGIQQYTDIDQDLRHLFLNTRQTTLKWALNNIEALSSRGRREGKLQAPVSKKVPFLCPTNN---TRSPSPPTSIEHLRPGDIDIIAAFGDSLSAGNGILSNNAIDMINEFRGLTFSGGGLANWRRFVTLPNILKIFNPKLYG---FAVSNSLVINHRSSRLNIAEPMIMSRDLPFQARVLIDLLRRDRHVDMKRHWKLLTVYVGNNDICSDLCHWDTPQSFLDQHARDLRQAFRLLRDHVPRLLINLIVVPNIPLVLSTMTKVPLQCFVVHRVGCHCLINDRLNRTEFNERMDTLTRWQQLDMEIARLPEFRRQDFAIVAHPMLTKLTAPTLPDGSTDWRFFSHDCFHFSQRGHAIISNLLWNSMLLPDDQKPRPSVVPELFERVVCPTAEQPYLVVRPS----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VW80-1", "uniprot_id": "Q9VW80_DROME", "id": "Q9VW80-1", "name": "Phospholipase B1, membrane-associated", "aln": "-MSSSRLICFGLLFLLAFGHVTSQR-----TSLDVALKNV------YRP----------------LRLLGLAFTGRSGDDPQN-VQRLQIAGKTQK--SNPRTRALLEFCDADHGPGKRSPERPTSVHRLRPGDIDVIGAMGDSLTAGNGIFATNLLHVTVENRGVVWSIGGQYDWRKYLTLPNILKEFNPNLYG---YAIKDGISTD-RSSRFDVAELAAMSRDMPHMAKVLVRRMQRDPRVNMTSDWKLVTLFIGNNDFCTDICYYPEPEKTVDWHERNMLKTYRYLRDNVPRLMLNIVPAPNLR-FLTNLTGLPPICYSTLRFECPCLMGKGKGQLDYLEG--IMKRWIAKDFEIANREEFNTETFTINVQPFSQFQDFPRTRSGQTDTRFFSEDCFHLSQRGHAAAANSIWNNMLELPGHKS--GFATHLFETFRCPSEMRPFLITRENSRPEFVISSKK-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M9PTB0-1", "uniprot_id": "A0A8M9PTB0_DANRE", "id": "A0A8M9PTB0-1", "name": "Phospholipase B1, membrane-associated", "aln": "---MEWLFIALATYLLALCPVEGDE------------------------------------------------WRLEYEEGLSHYSEEALRKEFPEKTRPISFKHPLFMCPDMS----PSSSVPTSVELVRAADIKVIAALGDSLTTAIGANATTVLGIPIEFRHVSWSIGGYGSFQDVITLANIIRLFNPSLVGPAPSKTVHGTPAPLCETGFNLAVTGHNTFNLPEQVRHLIDSLKTYEDIDFDVDWKLLTILIGMNDIC-DYCK-DKSLFSVENFIHYMTVSLEMLMNEVPRMIVNVVQILPMETLREVQKPTP--GCLLQRSFCSCLVKPAAGSSALKELVGVNLEFQKALEQLLHSDRFFKKDFAVVLQPFLKHADPPRLPNGKIDMSFFTPDCFHFTMKGHEELAKGLWNNMFQPEGEKFMVESFSDPIE-LVCPQVSHPYIYTRPAAAKSGSSRPESAGIRLAVLHLMPPLALLPLWTLAVNLASL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::* * .:. . . . . : :* *.. ***:. :*..**.:*.*:****::. * :.. : : * * : :* ** .:: :**.**:: ***.* * .. .: :::* : ::* .: *: :: ::: .***:*: :* **:* * * . :: . : : : . * :.***:::*:: : . . * * * **: . * .: :: . .* : *:: :*: * .*. * **: ****:: :** :: :**.*: ..* .. :* . ** :*:: .* ", "identical_positions": 78, "similar_positions": 116, "identity": "15.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130603-15", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9Q7U0-1", "uniprot_id": "E9Q7U0_MOUSE", "id": "E9Q7U0-1", "name": "Calcium-activated potassium channel subunit beta", "aln": "-------MQPFSIPVQITLQGGR------RRQGRTALPASGKIN------GDPLKVHPKLP-SSAGEDRAMLLGVAMMASSVLMFFLLGTTVLKPFMLRSPREESNCTTVHTHIVDDGLDFSFTCEGSCQDHGRSPCLQVFVNLSHSGQK--VLLHYDDEAIRTNPK------CFYTPKCHGDRDDLLNSVLDIKEFFDHNNGT-FPCFYSPDGPLG--VVLRKSGHKVVFHCLFWPLLTLLGGALIVGLVRLTQHLSFQCEQYSTVVRA------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPA1-1", "uniprot_id": "KCMB3_HUMAN", "id": "Q9NPA1-1", "name": "Calcium-activated potassium channel subunit beta-3", "aln": "--------MDFSPSSELGFHFVAF---ILLTRHRTAFPASGKKRETDYSDGDPLDVHKRLP-SSAGEDRAVMLGFAMMGFSVLMFFLLGTTILKPFMLSIQREESTCTAIHTDIMDDWLDCAFTCGVHCHGQGKYPCLQVFVNLSHPGQK--ALLHYNEEAVQINPK------CFYTPKCHQDRNDLLNSALDIKEFFDHKNGTPFSCFYSPASQSEDVILIKKYDQMAIFHCLFWPSLTLLGGALIVGMVRLTQHLSLLCEKYSTVVRDEVGGKVPYIEQHQFKLCIMRRSKGRAEKS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IRB9-1", "uniprot_id": "A0A0R4IRB9_DANRE", "id": "A0A0R4IRB9-1", "name": "", "aln": "MLLNQSPRGSFSVPVNITLQGARRRHMRDVIHHQAQLHDSGGNWRKERELKCNEKARAQIPDSSVGEDRAVLLGFLMMTCSILMYLMVGILMVKPCIHSDWISSVNCSLVHIDLSDEVMD--------CRGIVNFKCLRALVNITTSNKTSSLQLYYDEDAVNSRLKTNSFSQCFYTPKCQRNKTEQETEARNIKQALITQREN-LTCFLSP-SHPEDAICRRKYNLEMALYYLLWPSLMLFGGIVLVGLVKLNQHLALLCSEISRDEFLDNQSNQAEGRIYQLLKCRSGETAEQHKPLS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** . :: :: : :: : ** ..: ::* **.*****::**. ** *:**::::* ::** : .. .*: :* .: *: :* *:. . **:.:**:: ..:. *:*:::*:. . * *******: :: : ... :**: : :. . :.** ** . : :* . :: *:** * *:** ::**:*:*.***:: *.: * ", "identical_positions": 65, "similar_positions": 86, "identity": "21.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130603-17", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K0L0-1", "uniprot_id": "ASB2_MOUSE", "id": "Q8K0L0-1", "name": "Ankyrin repeat and SOCS box protein 2", "aln": "----------------------------------------------------------MATEISTRGRQ-RAIGHEEYSLYSSLSEEELLQMAIEQSLADKTRG---------------PTPAEASASSQTNHQP--GHFHPWTRSPSSPENPPAR-------APLGLFQG-------VMQKYS-SNLFKTSQMAAMDPVLKAIKEGDEEALKIMIQD-GKNLAEPNKEGWLPLHEAAYYGQLGCLKVLQQAYPGTIDQRTLQEETALYLATCREHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVRILVRYNADANHRCNRGWTALHESVSRNDLEVMEILVSGGAKVEAKNVYSITPLFVAAQSGQLEALRFLAKHGADINTQASDSASALYEASKNEHEDVVEFLLSQGADANKANKDGLLPLHVASKKGN-----------------YRIVQMLLPVTSRTRVRRSGISPLHLAAERNHDAVLEALLAARFDVNAPLAPERARLYEDRRSSALYFAVVNNNVYATELLLLAGADPNRDVISPLLVAIRHGCLRTMQLLLDHGANIDAYIATHPTAFPATIMFAMKCLSLLKFLMDLGCDGEPCFSCLYGNGPHPPA-PRPG-RFHDAPVDDKAPSVVQFCEFLSAPEVSRWAGPIIDVLLDYVGNVQLCSRLKEHIDSFEDWAVIKEKAEPPRPLAHLCRLRVRKAIGKYRIKLLDTLPLPGRLIRYLKYENTQ---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5U2S6-1", "uniprot_id": "ASB2_RAT", "id": "Q5U2S6-1", "name": "Ankyrin repeat and SOCS box protein 2", "aln": "----------------------------------------------------------MSTEISTRGRQ-RAIGHEEYSLYSSLSEEELVQMAIEQSLADKTRG---------------PTPAETSVSSQTNHQP--GHIHPWTRSSSPPESPPAR-------APLGLFQG-------VMQKYS-SNLFKTSQMAAMDPVLKAIKEGDEEALKAMIQD-GKNLAEPNKEGWLPLHEAAYYGKLGCLKVLQRAYPGTIDQRTLQEETALYLATCREHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVRILVQYNADANHRCNRGWTALHESVSRNDLEVMEILVSGGAKVEAKNVYSITPLFVAAQSGQLEALRFLAKHGADINTQASDSASALYEACKNEHEDVVEFLLSQGADANKANKDGLLPLHVASKKGN-----------------YRIVQMLLPVTSRTRVRRSGISPLHLAAERNHDAVLEALLAARFDVNTPLAPERARLYEDRRTSALYFAVVNNNVYATELLLLAGADPNRDVISPLLVAIRHGCLRTMQLLLDHGANIDAYIATHPTAFPATIMFAMKCLSLLKFLMDLGCDGEPCFSCLYGNGPHPPA-PRSG-RFNDAPVDDKAPSVVQFCEFLSAPEVSRWAGPIIDVLLDYVGNVQLCSRLKEHIDSFEDWAVIKEKAEPPRPLAHLCRLRVRKAIGKYRIKLLDTLPLPGRLIRYLKYENTQ---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96Q27-2", "uniprot_id": "ASB2_HUMAN", "id": "Q96Q27-2", "name": "Ankyrin repeat and SOCS box protein 2", "aln": "----------------------------------------------------------MATQISTRGSQ-CTIGQEEYSLYSSLSEDELVQMAIEQSLADKTRG---------------PTTAEATASACTNRQP--AHFYPWTRSTAPPESSPAR-------APMGLFQG-------VMQKYS-SSLFKTSQLAPADPLIKAIKDGDEEALKTMIKE-GKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTIDQRTLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQHNADTNHRCNRGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEALRFLAKYGADINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGN-----------------YRIVQMLLPVTSRTRIRRSGVSPLHLAAERNHDEVLEALLSARFDVNTPLAPERARLYEDRRSSALYFAVVNNNVYATELLLQHGADPNRDVISPLLVAIRHGCLRTMQLLLDHGANIDAYIATHPTAFPATIMFAMKCLSLLKFLMDLGCDGEPCFSCLYGNGPHPPA-PQPSSRFNDAPAADKEPSVVQFCEFVSAPEVSRWAGPIIDVLLDYVGNVQLCSRLKEHIDSFEDWAVIKEKAEPPRPLAHLCRLRVRKAIGKYRIKLLDTLPLPGRLIRYLKYENTQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58I5B0-1", "uniprot_id": "A0AC58I5B0_DANRE", "id": "A0AC58I5B0-1", "name": "", "aln": "MVALQFALSSHSKKVTVSSPDWASWRVCVEFACSPRGGLGFFQELRFPPQSKDIGTIMAATHVSLPGTTGTNLEFADYSLYSNLSDDELLHLAIERSLADAHSSGSGTENLKTPAALNKPSSAAATAACQTPSRPPQQQQRQQTVQAACPANPPREKIDLENVCSVSHFVTGYGKPMVAYRRYDGSMQLVPEPEEELEPIAKAISEGDVGTVRLMVKQPGCNLLKPNKEGWIPLHEAAYYGQDQCVKILLRAQPGMINQRTLRDQTPLMLAVSRENLACVEILLEKGADPEIPNKEKETPLYKACEKENPALVAMLLNHGALVNKSCIQGWTALHESVCRNNVEICEMLMKAGAKVSLPNKYGITPIFVAAQSGKVEALRMLLKNGADLNSQASDGATALYEACKNGHEDIVEFLLSQNADANKAGKTGLLPIHIAAQRGKDGKDLLTFGCTRKNISATKIIAMLIPATSRARVRRSGISPLHLAAERNRNDIVEVLIEAGFDVNAMLSEDRSMMYEDRRSTALYFAVINNNIEATTMLLEAGANPNLDTFKPLLVALRQGCIQTVTLLVEHGADVNANIPTHPTSFPASVMFCMKYLSLLKYLMDNGCDALSCFNCVYGSNPHPPIKPRRNPRYDSDESREK--TCVLFCEVISTENYSRWSGPIIDVLLDYVGHVKLCARLVEHLDSYHEWQCIKEKAMPPRPLMQLCRLKIRTLLGINRLKKIHKLPVPPRLIKFLNHQEREYEM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.:* * : :*****.**::**:::***:**** . *:.* ::.:. * :* : * ..: * ..* . ..:. * . ::*. * : .. :*: ***.:** ::: *::: * ** :******:*********: *:*:* :* ** *:****:::*.: **..* :* *: **: **:*:*.**.:*********::*. * :*:.:.* .*: * :*********.**::*: ::*:..****. * *.***:*******::****:* * ***:*:****.*:*****.** **::*******.*****:.* ****:*:*:::*: :*: **:*.***:*:****:**********:: ::*.*: * ****: *: :*: :*****::******:***: ** :** **:** *.:.*****:*:**::*: **::***:::* *.****:***::**.** *****:*** ***. .**.*:**..**** *: . *:.. :* : * ***.:*: : ***:************:*:**:** **:**:.:* ***** ***** :****::*. :* *:* :..**:* ***::*:::: : ", "identical_positions": 326, "similar_positions": 198, "identity": "43.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130603-21", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A571BF63-1", "uniprot_id": "ANKF1_MOUSE", "id": "A0A571BF63-1", "name": "Ankyrin-repeat and fibronectin type III domain-containing 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MLCLEKLVAVLLKTQRTSDAYKKGPWKSQRYTVSGSRVAYKRLNCDDIWARKKSRRIPMVPGGTYSPMPESQPLEDSPKALPVLGEQSNSDNDINEPVFIWGIS-DKAAQRKSISAGEGSFRLQQEKQQPLVHRPGRGKGRLRLPHRLPFKDRHFTCSKIIGRRFACFAQRLSYRRKQSQCDLLNESTGHLPATCSSAASKSLSWNYCSKMTQQMQNLHLSQSKKHSAPSSPNAAKRLYRNLSEKLKGSHSSFDEAYFRTRTDRLSLRKTSVNFQGNEAMFEAVEQQDLDAVQLLLYQYTPEELDLNTPNSEGLTPLDIAIMTNNVPIARILLRTGARESPHFVSLESRAMHLNTLVQEAQDRVSELSAQVENEGFTLDNTEKEKQLKAWEWRYRLYRRMKTGFEHARAPEVPANACLMVSSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSKDFSPLAGEIIMDNLQTLRCTITGLTTGQQYFVQVSAYNMKGWGPAQTTTPVCASPSNWKDYDDREPRHKGQSEVLESLLQQVRALHQHYSCRESSKLQTTGRKQSVSRSLKHLFHSSNKFVKTLKRGLYIATIFYYKDNMLVTNEDQIPIVEIDDSHTSSITQDFLWFMKLSCMWEDIRWLRQSVPISMSSSTVLQTRQKMLAATAQLQNLLGTHNLGRLYYEPIKDRHGNILIVTIREVEMLYSFFNGKWMQISKLQSQRKSLSTPEEPTALDILLITIQDILSYHKRSHQRLSPGLYLGYLKLCSSVDQIKVLVTQKLPNILCHVKIRENHNISKEEWEWIQKLSGSESMESVDHNADCPMQLFFYELQMAVAALLKQINIPRHQARNFRLYTQEVLEIGHNVSFLLLLPASDDVCTAPGQNNPYTPHSGFLNLPLQMFELVHFCSYREKFISLYCRLSAVVELDSLNTQQSLREAISDSEVAAAKQRHQQVLDFIQQIDEVWREMRWIMDALQYARYKQPVSGLPITKLIDSSSEQNLKKISSTSS-HIDCLPSTSPSPEMHRRKAVSESQPCSDEEGCSEVFLPTDSDYDSSDALSPRDLDLVYLSSHDIAQQALSGLSGSAPDVLQVHDMKASMGPGQDPQGPGQGPDTDHSCVEFLHSLTLTGLAPKNHAKMVAGTRPPLGFLGKRKPGK-HQHYGGFSRHHRWLRMHSETQSLSLSEGVYTQHLSQACGLAEDPGEAEGPGPVVDGPRGLPLAHAASLPEERRSCLQDPRRPLQRVYVEPYSDTLAGQDPKLWTSLSPTPAGRSSLP--------SSTSSEMSPD--PTSPVSEILSSML", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N957-1", "uniprot_id": "ANKF1_HUMAN", "id": "Q8N957-1", "name": "Ankyrin repeat and fibronectin type-III domain-containing protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNEK-------------------RLLFKDRHFTCSKIIGRRFACFAQRLSHRRKQSQCDLLNESTGQLPTTCSSAASNSINWNCRVKMTQQMQNLHLCQSKKHSAPSSPNAAKRLYRNLSEKLKGSHSSFDEAYFRTRTDRLSLRKTSVNFQGNEAMFEAVEQQDMDAVQILLYQYTPEELDLNTPNSEGLTPLDIAIMTNNVPIARILLRTGARESPHFVSLESRAMHLNTLVQEAQERVSELSAQVENEGFTLDNTEKEKQLKAWEWRYRLYRRMKTGFEHARAPEMPTNVCLMVTSSTSLTVSFQEPLSVNAAVVTRYKVEWSMSEDFSPLAGEIIMDNLQTLRCTITGLTMGQQYFVQVSAYNMKGWGPAQTTTPACASPSNWKDYDDREPRHKGQSEVLEGLLQQVRALHQHYSCRESTKLQTTGRKQSVSRSLKHLFHSSNKFVKTLKRGLYIAVIFYYKDNILVTNEDQVPIVEIDDSHTSSITQDFLWFTKLSCMWEDIRWLRQSIPISSSSSTVLQTRQKMLAATAQLQNLLGTHNLGRVYYEPIKDRHGNILIVTIREVEMLYSFFNGKWMQISKLQSQRKSLSTPEEPTALDILLITIQDILSYHKRSHQRLFPGLYLGYLKLCSSVDQIKVLVTQKLPNILCHVKIRENNNISREEWEWIQKLSGSESMESVDHTSDCPMQLFFYELQMAVKALLQQINIPLHQARNFRLYTQEVLEMGHNVSFLLLLPASDDVCTAPGQNNPYTPHSGFLNLPLQMFELVHFCSYREKFISLYCRLSAVVELDSLNTQQSLREAISDSEVAAAKQRHQQVLDFIQQIDEVWREMRWIMDALQYARYKQPVSGLPITKLIDPSDEQSLKKINSTSSSHIDCLPSPPPSPEMHRRKTVSDSQPCSDEEACSEVFLPTNSDYDSSDALSPRDLDLVYLSSHDIAQQTLSGLSGSAPDVLQVHDVKTPLGPGQDPQG--EGPNPDHSCAEFLHSLTLTGFTPKNHAKTVSGGRPPLGFLGKRKPGK-HPHYGGFSRHHRWLRIHSETQSLSLSEGIYTQHLSQACGLAQEPKEAKRAGPALDDPRGLTLAHAASLPEERNSSLQDARPSVRRLYVEPYAAAVVAQDEKPWASLSPPSGGRITLP--------SPTGPDVSQEGPTASPMSEILSSML", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GYA4-1", "uniprot_id": "A0AC58GYA4_DANRE", "id": "A0AC58GYA4-1", "name": "", "aln": "MLSQKFSPRRSGRHVTGSFESSFRFLREEDADVLRIRRGSMSPEPENKEKWLKMSYEAEKTCLLAPQESQTPCVCHTANEKYEIPGMGDDSVLEMLSYSKFSDLETWLCMPSTLLPRSRDSVCSLPPPSHENGTADTDRESRPPENTSINLSQCQERKTHLLPPSSLMPVSASPTSSTPLRTTSTPLPKPNRDSGQGGVSVRKR-RRLAASPGGLHWDASGSVLRDHDRGETPSLSEVKRFPRSVDSESLVPELWRDRAPLRKTISIDDRLLQQTPREHHRLLSRLERGKKKLRNINSLGATGRYETHKKSE-SRISRLAQRLNQR--QSDAALIKDFRPLFLLSGSAGSSQSLDRNFSISMSQQMQNLQLTQSKKGAGPASPSAAKRLYRNLSEKFKGSHSSFEDAYFFGRSDR--IRKVS-NIQSSEALFEAVEQQDLDAVQILLFQYTADELDLNTPNSEGLTPLDISIMTNNVPIAKLLLKAGGKESPHFVSLESRDAHLSALVQEAQRRASELSNQVMRESLSLETSDKEKQLKAWEWRCKLYKRMRTGFEHARQPEAPLMVRLSVTGSTTLTVSFQEPASMNSAVVTKYKVEWSCLKDFSLLAGELILENLQSLKCTITGLTMGRQYYVQVSAYNMKGWGPAQLSQPPSAVPSNWKDCDGRESRRRGHIEAMERLLQQVRATHQHYCCGDTSKLQNPSRKQSVSRSLKHLFHSSTKFVKSLKRGVYIASVFYHKDSLLVTNEDQIPIVEVDDSYSSSLMQDFLWFTKLSCMWEDVRWLRQSLAVSTSSSSTLQSRQKMLAAAGQLQNLLGTHNLGRVHYEPIKDRHGNVLLVTVREMDSLYSFFNGKWMQVSKLQSQRKSLSTPEEPYALDILLITIQDILAYQRRSQHRLSSGLYLGYLKLSSSVDQIKVLVPQRMPNMLCHTKIRDNWNVSRDEWEWLQSLSGPVEVERADQATGC---LLFSELQTAIKSLLHQINLPLHQAKHFRLYTHEVLELGHNVSFLLLLPASDDVCSAPGQTNPYTPHSGFLNLPLQMFELVHFCSYKEKFISLYCRLSSVLDLDALITQQAFREAITDSEVSTAKQRHQHILDYIQQLDEMWREVRWITNALQYARYKQPLGWVPITWLVDVSVEPPVQKNDSTSS-NTDYVPTPSPSPEMRRRKPTIESQPGSDEEGCSEVFLPTDSDYDSSDALSPRDLDLVYSSAQDLSHQAVHVLSGSAPDVLQMHDLKYSVCS--------KSILETESCTKDLEDLSLSSYSVKTTDKPSRSKFLADAPTKRKLLSKSHPQRSYFGGPHRWLRVQSESHTPSLSEGIYTRQSDIDLPLETPLSIPHSP------------TTSYSLDEYRQP-YRESKPNVRRIFVESCSKTSPCRDAPHWEEEEEKGSRGATASGARPGYSSTSEAQDVDSDEQTNEQVSEILSSTL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: * ..*: * .* *:: :****. * **:. *::: : : *:.:*:*:. * .*:******:* **** :.*:**.************:*******::*** *:** :**.* *:*..**:********:****:**:***.:*****************:*********::**::*.:*********** **.:****** *.**** ** .*.::*:.::*********** :**:**:******* ** * . * *:.**:******** *:*:****:****** :*** ****:*::***:*:******* *:**:*************** : * .* ****** *.**.*::*: *.:* ******* ****.* :::***...****************.****:****:*** :**:**.:*******:****:***::**: ****** ********:******:.:* ***:.**:*******:.*************::**********:*:**:**:: ***********:**************** *************:*::**::** .*********.**********.*::**:***.***:* *:*::****:*.***. .:* .*: :.* *:* *** *: :**:***:* ***::*****:****:*****************:****.*************************:***********:*::**:* ***::****:****::******::**:***:**:***:*** :**********:. :*** *:* * * ::* .**** : * :*:..*****:***.. :*** ****.********:****************** *::*:::*:: **********:**:* .: . :. .**.: *..*:*:. : *. * . . . :: .* * : . *. *****::**::: *****:**:: . * .. . : : ** * *.. ::.: ::*::**. : : :* * . . . : . :. . ::. : . . :****** *", "identical_positions": 686, "similar_positions": 273, "identity": "47.31%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130603-23", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R3T0-1", "uniprot_id": "M0R3T0_RAT", "id": "M0R3T0-1", "name": "", "aln": "MAERGPGLRYAEKLPTGSSPGDGTHLRCPGREAKRCCPCDCCCCRACGCPEPPRPADRAVGRATRPGFTIITGGASCKKLFPPSCKPRAWGHHFRFLHCVPSSLAPASAPAMGSLLRNLSRGGRVGAALWCWRKARGLGGPQCPSWVTPRLSRSRGIPGLEDRPALGG----------VMGKHHFSSWGCCQSLP---RGRHSVLHRHRAPVQTTDSRRKLGTDHREEGFQVGTEVDREPKASLPRGNLIGPPDSLPPELEP-PTNCCMSGCPNCVWVDYAEALLRLYQDGGEKALALLEEHVTDENLKAFLRMEIRLRMQSGA---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CR10-1", "uniprot_id": "OXLD1_MOUSE", "id": "Q9CR10-1", "name": "Oxidoreductase-like domain-containing protein 1", "aln": "---------------------------------------------------------------------------------------------------------------MGSPLQTLSRGGRVRAALWCWTQARGLSGRQCPNRVARSLSCSRGFPVRGGRPALGGTMVSVLTESFLQGTQHFSSWDCCQSL-----------HRHRAPVQVTDSRRNLGMDHREEGFQVGTEDDREPKASLPRGNPTGPPCSLPPELEP-PTNCCMSGCPNCVWVDYAEALLRLYQDGGEKALAILEEHVTDENLKAFLRMEIRLRMQSGA---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5BKU9-1", "uniprot_id": "OXLD1_HUMAN", "id": "Q5BKU9-1", "name": "Oxidoreductase-like domain-containing protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------MLLRRVVEGGRAVAA------------------------------------AVRG-----------SGARRFSSPDCCQRLP---GGG-SFLQRHHPGAQAPDGRRKFGTDHVEVGSQAGADGTRPPKASLP------------PELQP-PTNCCMSGCPNCVWVEYADRLLQHFQDGGERALAALEEHVADENLKAFLRMEIRLHTRCGG---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U356-1", "uniprot_id": "A0AB32U356_DANRE", "id": "A0AB32U356-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSLNAGSCLQRLC---IFSMSLFRNKPPPSQIT------CVHHTACEQQCSSPDSSSSVSSVKKPLIPSSETGDEGPPSA-PTHCCMSGCHNCVWIEYAEKLLKYYSDGGERALEAIEKNVLDDNLKAYLKMEIKLLKKT-----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBA6-1", "uniprot_id": "Q9VBA6_DROME", "id": "Q9VBA6-1", "name": "Oxidoreductase-like domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLAPLGFSCPRCLLLRRGAERWASLARQLSGSSSQDDASSKDAAAQEAASGCPPNSTTTGTDTPKAKDKTTKGRKRLRNIEIPPEPTTCCMSGCANCVWLDYAQTLAKLLGDNDEEAREIVLSKITDPNLKMFLSLELRQMAKQREEKAAAEKAAKQGKPKKSSPPP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. * : . * .. .: .. . ** ****** ****::**: * : *..*.* : .:: * *** :* :*:: : ", "identical_positions": 26, "similar_positions": 28, "identity": "7.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130603-30", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LWD8-1", "uniprot_id": "F1LWD8_RAT", "id": "F1LWD8-1", "name": "", "aln": "----------------------------------------------------------------------------------------MGLEG-PE----------------------TAAQPQVTLLPTINGSNPQYDSVDGHWPETPEKSPCVAGIIPVIYYS---VLLSLGLPVNVLTTVVLARLAVRTKKPSYHYLLALTASD---IVTQVV----IVFIGFLLQGAVLARQVPQAVVRTAN--ILEFAANHASVWIAVLFTVDRYNALCRPLRHRATSSPGRTHRAIAAVLSVTLLTGIP------FYWWLDVWRDADPPSTMDKLLKWAH----------------CLIVYFIPCNVFLVTNSAIILRLRKRGQR-------------GLQPWMSKSTAILLGVTSLFALLWAPRISVMLYHLYVAPVHRDWR---VHLALDIANMLAMLNTAVNFGLYCFISKTFRATVRQVIQD----------VHMSCALKSQPKGTVTELVLKS----VGAEL--------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TQN9-1", "uniprot_id": "GP142_MOUSE", "id": "Q7TQN9-1", "name": "G protein-coupled receptor 142", "aln": "----------------------------------------------------------------------------------------MHLNSNPNSYICDAYQHADLLWSLSPHVLTKAVQPQVTLLPTVNGSNPRYDGVDGHWPESPERSPCVAGIIPVIYYS---VLLSLGLPV------ALARLAARTRKPSYHYLLALTASD---IVTQVI----IVFVGFLLQGAVLARQVPQAVVRTAN--ILEFAANHASVWIAVLFTVDRYNALCRPLRHRATSSPGRTHRAIAAVIGVTLLTGIP------FYWWLDVWRDADPPSTMDKLLKWAH----------------CLIVYFIPCNVFLVTNSAIILRLRKRGQR-------------GLRPLVSKSTAILLGVTSLFALLWAPRIIVMLYHLYVAPVHRDWR---VHLALDIANMLAMLNTEVNFGLYCFISKTFRATVRQVICD----------VHMACALKSQPKQTVVELMLKS----VGTEL--------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z601-1", "uniprot_id": "GP142_HUMAN", "id": "Q7Z601-1", "name": "G protein-coupled receptor 142", "aln": "MSIMMLPMEQKIQWVPTSLQDITAVLGTEAYTEEDKSMVSHAQKSQHSCLSHSRWLRSPQVTGGSWDLRIRPSKDSSSFRQAQCLRKDPGANNHLESQGVRGTAGDADRELRGPSEKATAGQPRVTLLPTPHVSG-LSQEFESHWPEIAERSPCVAGVIPVIYYS---VLLGLGLPVSLLTAVALARLATRTRRPSYYYLLALTASD---IIIQVV----IVFAGFLLQGAVLARQVPQAVVRTAN--ILEFAANHASVWIAILLTVDRYTALCHPLHHRAASSPGRTRRAIAAVLSAALLTGIP------FYWWLDMWRDTDSPRTLDEVLKWAH----------------CLTVYFIPCGVFLVTNSAIIHRLRRRGRS-------------GLQPRVGKSTAILLGITTLFTLLWAPRVFVMLYHMYVAPVHRDWR---VHLALDVANMVAMLHTAANFGLYCFVSKTFRATVRQVIHD----------AYLPCTLASQPEGMAAKPVMEPPGLPTGAEV--------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PUW3-1", "uniprot_id": "A0A8M1PUW3_DANRE", "id": "A0A8M1PUW3-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------MIDWHNGTTPGQREDE---RSAQERSECVLAYIPVVYYS---ALLCVGVPVNILTLVALYRLVVRTQKALYVYLLALTGSD---ILSQLF----IIFVGFLLETAVFHRDVPVLLLRSVS--MMEFSANHASIWATVPLTVDRYVALCHPLLHRQISYPARARRIIAVVLTLALASGVP------FFWWSDMWRVSHEPNNLDTALIWTH----------------VTIIYFLPCCIFLVLNSLIILRLRKRQRQQ--MCQDESGQQLAVPSKLGKTTAMLLAVTSVFAVLWAPRTGVVLYHLYVTSVHNDWR---VHLAYDLANMLAMLNTAVNFFLYCFVSKPFRAAVRDVLLFRGAP------LHPRRPLRNQRTPANASTSSISSTKRSQREVTPLSPKRADNNKM-------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8SWR3-1", "uniprot_id": "SPR_DROME", "id": "Q8SWR3-1", "name": "Sex peptide receptor", "aln": "--------------------------------------------------------------------MDNYTDVLYQYRLAPSASPEMEMELADPRQMVRGFHLPTNESQLEIPDYGNESLDYPNYQQMVGGPCRMEDNNISYWNLTCDSP--LEYAMPLYGYC---MPFLLIITIISNSLIVLVLSKKSMATPTNFVLMGMAICD---MLTVIFPAPGLWYMYTFGNHYKPLHPVSMCLAYSIFNEIMPAMCHTISVWLTLALAVQRYIYVCHAPMARTWCTMPRVRRCTAYIALLAFLHQLPRFFDRTYMPLVIEWNGSPTEVCHLETSMWVHDYIGVDLYYTSYYLFRVLFVHLLPCIILVTLNILLFAAMRQAQERRKLLFRENRKKECKKLRETNCTTLMLIVVVSVFLLAEIPIAVVTAMHIVSSLIIEFLDYGLANICIMLTNFFLVFSYPINFGIYCGMSRQFRETFKEIFLG--------------RLMAKKDSSTKYSIVNGARTCTNTNETVL------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZW5-1", "uniprot_id": "FMAR_DROME", "id": "Q9VZW5-1", "name": "FMRFamide receptor", "aln": "-------------------------------------------------MSGTAVARLLLRLELPSPGVMPPPPTDYDYGGPISDDEFLASAMATEGPTVRYDLFPQNNSQPTLQIVLNHTEVQTDLQYPHYEDLGLDPDPNWTRICEDVYNPLLENNRIEFWVCGVLINIVGVLGILGNIISMIILSRPQMRSSINYLLTGLARCDTVLIITSILLFGIPSIYPYTGHFFGYYNYVYPFISPAVFP--IGMIAQTASIYMTFTVTLERYVAVCHPLKARALCTYGRAKIYFIVCVCFSLAYNMPR-----FWEVLTVTYPEPGKDVILHCVRPSRLRRSETYINIYIHWCYLIVNYIIPFLTLAILNCLIYRQVKRANRER-------QRLSRSEKREIGLATMLLCVVIVFFMLNFLPLVLNISEAFYSTIDHKITK---------ISNLLITINSSVNFLIYIIFGEKFKRIFLLIFFKRRLSRDQPDLIHYESSISNNGDGTLNHRSSGRFSRHGTQRSTTTTYLVATGGPGGGGCGGGGGNNSLNNVRLTQVSGSPGLVKIKRNRAPSPGPVVYFPAREMQRSASTTNSTTNNNTSIGYDWTLPDSKKLGHVSSGF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : : : . * .:: .* :: :. . . * : : : .: *:: :. .:::** :*:. * . *.: :: :* : : :::* : * : ::: . . :* :* : .* : * : : . ::*:. : ** :* ... *: . :: : .: . ", "identical_positions": 21, "similar_positions": 76, "identity": "3.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130603-37", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08726-1", "uniprot_id": "GALR2_RAT", "id": "O08726-1", "name": "Galanin receptor type 2", "aln": "MNGSGSQGAENTSQEGGSGGWQPEAVLVPLFFALIFLVGTVGNALVLAVLLRGGQA-VSTTNLFILNLGVADLCFILCCVPFQATIYTLDDWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLALLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDLCTFVFSYLLPVLVLSLTYARTLRYLWRTVDPVTAGSGSQRAKRKVTRMIIIVAVLFCLCWMPHHALILCVWFGRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRKICAGLLRPAPRRASGRVSILAPGNHSGSMLEQESTDLTQVSEAAGPLVPPP------ALPNCTASSR----------TLDPAC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88854-1", "uniprot_id": "GALR2_MOUSE", "id": "O88854-1", "name": "Galanin receptor type 2", "aln": "MNGSDSQGAEDSSQEGG-GGWQPEAVLVPLFFALIFLVGAVGNALVLAVLLRGGQA-VSTTNLFILNLGVADLCFILCCVPFQATIYTLDDWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLALLFSGPYLSYYSQSQLANLTVCHPAWSAPRRRAMDLCTFVFSYLLPVLVLSLTYARTLHYLWRTVDPVAAGSGSQRAKRKVTRMIVIVAVLFCLCWMPHHALILCVWFGRFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRKICAGLLRRAPRRASGRVCILAPGNHSGGMLEPESTDLTQVSEAAGPLVPAP------ALPNCTTLSR----------TLDPAC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43603-1", "uniprot_id": "GALR2_HUMAN", "id": "O43603-1", "name": "Galanin receptor type 2", "aln": "MNVSGCPGAGNASQAGGGGGWHPEAVIVPLLFALIFLVGTVGNTLVLAVLLRGGQA-VSTTNLFILNLGVADLCFILCCVPFQATIYTLDGWVFGSLLCKAVHFLIFLTMHASSFTLAAVSLDRYLAIRYPLHSRELRTPRNALAAIGLIWGLSLLFSGPYLSYYRQSQLANLTVCHPAWSAPRRRAMDICTFVFSYLLPVLVLGLTYARTLRYLWRAVDPVAAGSGARRAKRKVTRMILIVAALFCLCWMPHHALILCVWFGQFPLTRATYALRILSHLVSYANSCVNPIVYALVSKHFRKGFRTICAGLLGRAPGRASGRVCAAARGTHSGSVLERESSDLLHMSEAAGALRPCPGASQPCILEPCPGPSWQGPKAGDSILTVDVA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R332-1", "uniprot_id": "GAL2A_DANRE", "id": "F1R332-1", "name": "Galanin receptor 2a", "aln": "MNASQQIHVFSS-------HWKVESVIISLIFSMIFLVGTVGNCLVLAVLIRNGQMNTKSTNLFILNLGLADLCFIVFCVPLQATIYTMDEWVFGAFVCKAVHFIIYLTMYASIFTLAAVSLDRYLAIRYPLRSRETRTPRNALTSISLVWALSLFFSSPYLSYYQQMDLDGTTVCIPAWSVHHRQAMDICTFIFGYLIPVLILGITYARTIRYLWTSVDPMQDMSESRKAKRKVTKMIIIVAVLFCLCWLPHHLVILCMWFGHFPLNHTTYVLRILSHLVAYANSCLNPIVYALVSKHFRKGFKKVFGCAFR---NRVVNRIHTVQP-AQTVSLMEAASSEGSNHCDGSTRGRLWSK-----SSKKMMTSAF---------MTFNVT-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * . .: *: *:*::.*:*::*****:*** ******:*.** ..:*********:******: ***:******:* ****:::******:*:***:** ******************:*** *******::*.*:*.*:*:**.****** * :* . *** ****. :*:***:***:*.**:***:*.:*****::*** :***: * :::******:**:***.******:*** :***:***:***.::**.********:*****:****************:.: . : *. .*: :: .::* *:: : .:.: . : *.: : ", "identical_positions": 207, "similar_positions": 93, "identity": "53.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130603-38", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35181-1", "uniprot_id": "NRG3_MOUSE", "id": "O35181-1", "name": "Pro-neuregulin-3, membrane-bound isoform", "aln": "MSEGAAGASPPGAASAAAASAEEGTAAAAAAAAAGGGPDGGGEGAAEPPRELRCSDCIVWNRQQTWLCVVPLFIGFIGLGLSLMLLKWIVVGSVKEYVPTDLVDSKGMGQDPFFLSKPSSFPKAMETTTTTTSTTSPATPSAGGAASSRTPNRISTRLTTIT-----------------------RAPTRFPGHRVPIRASPRSTTARNTAAPPTVLSTTAPFFSSSTPGSRPPMPGAPSTQAMPSWPTAAYATSSYLHDSTPSWTLSPFQDAAAASSSS-------PSSTSSTTTTPETSTSPKFHTTTYSTERSEHFKPCRD-KDLAYCLNDGECFVIETLTGSHKHCRCKEGYQGVRCDQFLPKTDSILSDP-TDHLGIEFMESEDVYQRQVLSISCIIFGIVIVGMFCAAFYFKSKKQAKQIQEHLKESQNGKNYSLKASS--TKSESLMKSHVHLQNYSKADRHPVTALEKIMESSFSAPQSFPEVTSPDRGSQPIKHH-------SPGQRSGML-HRNTFRRAPPSPRSRLGGIVGPAYQQLEESRIPDQDTIPCQGIEVRKTISHLP----------IQLWCVERPLDLKYVSNGLRTQQNASINMQLPSRETN--PYFNSLDQKDLVGYLSPRANSVPIIPSMGLEETCMQMPGISDVKSIKWCKNSYSADIVNASMPVSDCLLEEQQEVKILLETVQEQIRILTDARRSEDFELASMETEDSASENTAFLPLSPTAKSEREAQFVLRNEIQ----------RDSVLTK-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P56975-1", "uniprot_id": "NRG3_HUMAN", "id": "P56975-1", "name": "Pro-neuregulin-3, membrane-bound isoform", "aln": "MSEGAAAASPPGAASAAAASAEEGTAAAAAAAAAGGGPDGGGEGAAEPPRELRCSDCIVWNRQQTWLCVVPLFIGFIGLGLSLMLLKWIVVGSVKEYVPTDLVDSKGMGQDPFFLSKPSSFPKAMETTTTTTSTTSPATPSAGGAASSRTPNRISTRLTTIT-----------------------RAPTRFPGHRVPIRASPRSTTARNTAAPATVPSTTAPFFSSSTLGSRPPVPGTPSTQAMPSWPTAAYATSSYLHDSTPSWTLSPFQDAASSSSS---------SSSSATTTTPETSTSPKFHTTTYSTERSEHFKPCRD-KDLAYCLNDGECFVIETLTGSHKHCRCKEGYQGVRCDQFLPKTDSILSDP-TDHLGIEFMESEEVYQRQVLSISCIIFGIVIVGMFCAAFYFKSKKQAKQIQEQLKVPQNGKSYSLKASSTMAKSENLVKSHVQLQNYSKVERHPVTALEKMMESSFVGPQSFPEVPSPDRGSQSVKHHRSLSSCCSPGQRSGML-HRNAFRRTPPSPRSRLGGIVGPAYQQLEESRIPDQDTIPCQGIEVRKTISHLP----------IQLWCVERPLDLKYSSSGLKTQRNTSINMQLPSRETN--PYFNSLEQKDLVGYSSTRASSVPIIPSVGLEETCLQMPGISEVKSIKWCKNSYSADVVNVSIPVSDCLIAEQQEVKILLETVQEQIRILTDARRSEDYELASVETEDSASENTAFLPLSPTAKSEREAQFVLRNEIQ----------RDSALTK-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5S2-1", "uniprot_id": "A0ACD6B5S2_DANRE", "id": "A0ACD6B5S2-1", "name": "", "aln": "--------------------MSERTALGATMETMTLEEPGGEQASPRAPGPLRCGPCAVWPRQQTWLCVVPLLMGFVGLGLSLMLLKWIVVGSVQDYVPTDLVDANRIGQDPIFLSKPSSLPKGSDASASTTSTTPSAAPGSATRAAEGTGTVQRTRIGQSSNHTASSSSSSGGGGGGLGGGSGNRAPHLHNRVGTRVTNITTTTRATNPAPPGGKEVTPRSTTVRKPNGEGGSRSASPSARAGPPSPTTTSTTTTTITTSTTTTQAAQPTSTPASPSKPGQRWNHGRSSKGPSTKPTRPHHRFRTLAPTTSTVRSEFFKPCQDSQEMAFCLNEGECFIIETVAGVHRHCRCKEGYRGLRCDQFVPKTDSILSDPTADELGIEFMESAETYQRQILSIFSIAMGISLLGVACMALYCKNKRQREKHRAHLTEIRNLRDCTVNASGLMSKSSPRLESSLQLQ-----KSRRVHGLSSPQAASIVLSSSKVSLPNQNRSFSMGKRCRSCSFSSSPALKHKVSNYRAVSKWTPPIPRAGHHLSGGSRDSLHSYKHLQEVEVNDVMPQALRRCQSHLDSNQQNRCNLNMQIMLSAHSKGKMSYTDVPCTRLDQGMTFPPPSFRAHSVPIIPSVQGPDFGGGGGNKLHNVGMGSSS-YNPINPETDSVANSSRSLASSSATVQEPQTLTCSESALMSRGQIKHKSLVTYTTALGSGTSSRRAKTVISMTVLGTGVKTTQYAASLLSKTTAGREEHSAFEEVKQGDGLQTPFTGDEKDSSFSSGVRGETSLDHPKS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* ** .*: : ** :.:...* ***. * ** ***********::**:*****************::********:: :****:*******:**. :::::*****..*:*.:. *:. * . **: : *** . . : . :* * *.*.* *. . .. *. . ..:**::* *. **:: :*:: : **.: : .:.::.*. **...:*..... : :.* ** ***.****:* :::*:***:****:***::* *:********:*:*****:********** :*.******** :.****:*** .* :** ::*: * *:* *.*:* :: : :*. :* :. :::**. :**. ::* ::** . : * .*.. :*: ..* .:.. :*. . *: **. : : :* . : :** **: *. . . .:: : :. :*: *** :*: :. . :. *: : .:.: ** .:: * : *:: *: * . : .* : .* : : .::: . ...: : . : . * : * : * *: . :. * . .:: : * .::: :* * ..** *..: * :: : :** ::. ", "identical_positions": 223, "similar_positions": 234, "identity": "28.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130603-43", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1AQL3-1", "uniprot_id": "TM235_MOUSE", "id": "B1AQL3-1", "name": "Transmembrane protein 235", "aln": "-MALLATLLLSAALGALLSFALLAAAVASDYWYILEVADAGG----LGGVQLFS-HSGLWRTCEGQNSCVPLIDPFASAGLEVSPSVQHLLSLHRTVMVVLPLSLVLIVCGWVCGLLSSLSQSVPLLLATGCYFLLGGALTLAGLSIYISYSHLAFVEAARTYGVTHVQNVHISFGWSLALAWASCASEVLSGALLLAAARLLSLSQRPG---VPHSVIL----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NFC5-1", "uniprot_id": "TM235_HUMAN", "id": "A6NFC5-1", "name": "Transmembrane protein 235", "aln": "-MARLGALLLAAALGALLSFALLAAAVASDYWYILEVADAGNGSAWPGRAELLSSHSGLWRICEGQNGCIPLVDPFASESLDVSTSVQHLILLHRAVIVVLPLSLVLLVCGWICGLLSSLAQSVSLLLFTGCYFLLGSVLTLAGVSIYISYSHLAFAETVQQYGPQHMQGVRVSFGWSMALAWGSCALEAFSGTLLLSAAWTLSLSPPICGHLSPQQVGGRGGD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9H0-1", "uniprot_id": "E7F9H0_DANRE", "id": "E7F9H0-1", "name": "", "aln": "MKITFGFVVVCGGLTGVLSFSCLALAIGTEYWYIIEDQRTNH-------TNPERSNSGLWGVTEDEKS--------NSEDTGYSESERQMEIMHCVIAILLPLSLVMLVFGGICGLVSSLARSRALLIGSASYFLLCSLLTLSGVSLYIRYSQKALEETERRMGREQMAQVHTSFGWSMGMAWISFLLEVMTGLLLLLAVKLVPLTQYED---SVAPI------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. :::...* .:***: ** *:.::****:* :. .: :**** *.::. * . * * ::: :* .: ::******::* * :***:***::* .**: :..**** . ***:*:*:** **: *: *: : * :: *: *****:.:** * *.::* *** *. :.*: : ", "identical_positions": 70, "similar_positions": 67, "identity": "31.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130603-44", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAF6-1", "uniprot_id": "ATPK_RAT", "id": "D3ZAF6-1", "name": "ATP synthase F(0) complex subunit f, mitochondrial", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASIVPLKEKKLMEVKLRELPSWILMRD-FTPSGIAGAFRRGYDRYYNKYINVRKGSISGINMVLAAYVVFSYCISYKELKHER----RRKYH--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P56135-1", "uniprot_id": "ATPK_MOUSE", "id": "P56135-1", "name": "ATP synthase F(0) complex subunit f, mitochondrial", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASLVPLKEKKLMEVKLGELPSWIMMRD-FTPSGIAGAFRRGYDRYYNKYINVRKGSISGISMVLAAYVVFSYCISYKELKHER----RRKYH--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PX83-1", "uniprot_id": "A0A8M9PX83_DANRE", "id": "A0A8M9PX83-1", "name": "", "aln": "MTNIIQCEELQTRLHCSAEQCPYCGKPFKRLKTHIPHCKMAPAAQSQKSIQAPKELSATSSRQKILKKTAAAETNVVIFNETQPSKSRRKGDLHNAESPLSSTKVKVSSSETLDTERPKSKWLAKRQKELERLQLLVPDSQKPSKPTSLSEHAGDKSFCEISKGPDQGTSQTNGKSTRGKKKLKMAQLSEQLSITKGEINSTG--------------SVPAKSSSVPRECIVEFKNPKLKTRVKCLEEIERCAKSQNKEFDLISGAKEHKALPIFTSKTSVWDHISYSLYYKRSFNLFVPYPVLQTSKDSA-------------------------------------------------------------------------------------------------------------VETKEISTMRQSEKLATALIKVSIAPSPVLSETNIRQPAEDTLNSRLQGVRSLSWAPEMKTDCSRIQLSTVPLGCCANEDIWMKNQLSGPSTLCKVPLFRRKFGDVRLNELGLWLGARAPVSPGEIVNMFKQGWQWYYRKYIDVRRGGVGGISMLLTGYCVLCYIWNYTHLKKDR----WRKYH--------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W141-1", "uniprot_id": "ATPK_DROME", "id": "Q9W141-1", "name": "Putative ATP synthase subunit f, mitochondrial", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAFGDYPAEYNPKVHGPYDPARFYGKADVPFGQVKLGEIGAWLGRRN-KTPNAVAGAVSRAWWRWQHKYVFPKRAGIAPFFQLTVASMTFFYLINYTKLKHHR----NYKYH--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9BSJ5-1", "uniprot_id": "CQ080_HUMAN", "id": "Q9BSJ5-1", "name": "Mitochondrial nucleoid-associated protein 1", "aln": "----------MSDNPPRMEVCPYCKKPFKRLKSHLPYCKMIGPTIPTDQKVYQSKPATLPRAKKMKGPIKDLIKAKGKELETENEERNSKLVVDKPEQTVKTFPLPAVGLERAATTKADKDIKNPIQPSFKMLKNTKPMTTFQEETKAQFYASEKTSPKRELAKDLPKSGESRCNPSEAGASLLVGSIEPSLSNQDRKYSSTLPNDVQTTSGDLKLDKIDPQRQELLVKLLDVPTGDCHISPKNVSDGVKRVR-TLLSNERDSKGRDHLSGVPTDVTVTETPEKNTESLILSLKMSSLGKIQVMEKQEKGLTLGVETCGSKGNAEKSMSATEKQERTVMSHGCENFNTRDSVTGKESQGERPHLSLFIPRETTYQFHSVSQSSSQSLASLATTFLQEKKAEAQNHHCVPDVKALMESPEGQLSLEPKSDSQFQASHTGCQSPLCSAQRHTPQSPFTNHAAAAGRKTLRSCMGLEWFPELYPGYLGLGVLPGKPQCWNAMTQKPQLISPQGERLSQVSLLERSSTHIRSLEPPAGLTTSN-FSLMRLLGAVQKGWIRCN---TTIRKSGFGGITMLFTGYFVLCCSWSFRRLKKLCRPLPWKSTVPPCIGVAKTTGDCRSKTCLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PIX9-1", "uniprot_id": "CQ080_MOUSE", "id": "Q6PIX9-1", "name": "Mitochondrial nucleoid-associated protein 1", "aln": "----------MGAAEPRMEVCPYCKKPFKRLKSHLPHCKMRGPSISADQNVSQSKPAAL--AQKEKSPTRDLTRAKEKELEVDRPKRAVKAETSRASWTAAASPLPEGILGSVRITKAEGENKDQNQFSFQALSQAKPEVTLQRVTTPWSPASDATSPKRELTQDVSESKGSPC-PSETEAPSLVSSVEPFLANQDRKYSSTQPHANPATSVGLKLGTVDPQRQKLRVKLLDVPLSDRHS-PKSGSHGVQRVTPSVLSREEGSQDGGHLLGVSAHPGNTKT--QKSESLLLGLHTGLLGKAPVREHQELG--LGMELSQSKGNTENRMSVTNVQEGAGLGQGGKDPITATKAKPHTALELR---NVFMP-----------ESGNQSLTSPAVTSTPEENAQFCGQSHVPAITLSVGSVRD--VLEPTSFYQPHTAQAGHCLMSYSAQYPVPKT-FVGHVAAVTSGAPPRSVGLEWFPELYPAYVGLGVLPRRPPPWSLAAQVPPLPTLQGRSVSKVPWWGRSSADSRSLEPLT-LTTSS-LPLMRLLGAVHKGWVQCN---TTIKKSGVGGLTMLFAGYFILCCNWSFKHLKLQH----WRK----------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * : . : . . :.: ::.... : : .. : .: .** . ", "identical_positions": 3, "similar_positions": 25, "identity": "0.48%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130603-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AB32U4L1-1", "uniprot_id": "A0AB32U4L1_DANRE", "id": "A0AB32U4L1-1", "name": "", "aln": "MGETLAAICLEACSWQGRVVGQALRPSTRPFPRKKSMASRRKGEKKKKTVELTEAKKQQHLDAEPSDGSTKEQMACKRKMKPQKKYIGAHVSISGGIWKAVESSVAMGGHAFALFLGSQRSWTRPVLDSKAAVKFQQACAEHGFDPVH-ILPHGSYLMNCGSPKEDVFSKSQAMLVDELSRCDALGLSQFNFHPGAAMDSSPEKCMEKIAQAINHAHQQTPAVITVLENMSGQGSTIGGQFSELKGIIDRVRDKTRVGVCLDTCHAFAAGYDISPPGGVKNMLDEFDRVVGLHYLRAVHLNDSKGKLGSHLDRHEDIGHGQIGITAFQEIVNEPRLDNIPLILETPGRQGFEYAEQIELLYSLCEKKVKK-------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22936-1", "uniprot_id": "APN1_YEAST", "id": "P22936-1", "name": "Apurinic-apyrimidinic endonuclease 1", "aln": "------------------------MPSTPSFVRS----------------------------------------------AVSKYKFGAHMSGAGGISNSVTNAFNTGCNSFAMFLKSPRKWVSPQYTQEEIDKFKKNCATYNYNPLTDVLPHGQYFINLANPDREKAEKSYESFMDDLNRCEQLGIGLYNLHPGSTLKGDHQLQLKQLASYLNKAIKETKFVKIVLENMAGTGNLVGSSLVDLKEVIGMIEDKSRIGVCIDTCHTFAAGYDISTTETFNNFWKEFNDVIGFKYLSAVHLNDSKAPLGANRDLHERLGQGYLGIDVFRMIAHSEYLQGIPIVLETPYENDEGYGNEIKLMEWLESKSESELLEDKEYKEKNDTLQKLGAKSRKEQLDKFEVKQKKRAGGTKRKKATAEPSDNDILSQMTKKRKTKKE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** .* *. .* :***:* :*** ::* .:. * ::**:** * *.*. * .: **:: ** :.::*: :****.*::* ..*..: .** ::*:*.**: **:. :*:***:::... : ::::*. :*:* ::* * *****:* *. :*..: :** :*. :.**:*:***:****:********.. .:*: .**: *:*::** ********. **:: * ** :*:* :** .*: *.:. *:.**::**** .:. *.::*:*: * .*. .: ", "identical_positions": 119, "similar_positions": 112, "identity": "27.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130603-67", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BVY0-1", "uniprot_id": "RL1D1_MOUSE", "id": "Q8BVY0-1", "name": "Ribosomal L1 domain-containing protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKGSASESPSASVAEATTTDVQVTPTALLQLDREQIRKAVEVISNRSKSKKNNNELLLS--------------------------------------------------------------------GSENLFLMVILWKIPEK-ELRVKVPLP-------------HSILSESSDVCLFTKDE---FDS-PEQTEGFYKKLLKKHGVNTISQIIPFKTLKTEYKAYEAKLRLLGSFEVFITDARIRRHLPSHIG-RHFYQRKKVPVSVNLLAKN------LSKEINRCITGTVLNISKRGSCSTIRIGHTG-METEHIVDNILAVSEMLSEKLPEKWQSVKLLFLKTEKS--VSLPIFSSFVTSQDEN-AVSLRSLRKQELKKRKRE-NAKLKKESKMLRKKSKKATSLLTQSGLAS---SAPAKSPGAQKKKTNKAHKKQ--------KVTEECEEAIPQLVPIG-ETPDKENVKMQENITGKTPKSKS-DPSTPKGKKRKALLATETPEASAPGTSGKK--------------------QKKDVQEFRKPEASSFSTPRKSGKKASNTPR--DKKTKAAHSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76021-1", "uniprot_id": "RL1D1_HUMAN", "id": "O76021-1", "name": "Ribosomal L1 domain-containing protein 1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEDSASASLSSAAATGTSTSTPAAPTARKQLDKEQVRKAVDALLTHCKSRKNNYGLLLN--------------------------------------------------------------------ENESLFLMVVLWKIPSK-ELRVRLTLP-------------HSIRSDSEDICLFTKDE---PNSTPEKTEQFYRKLLNKHGIKTVSQIISLQTLKKEYKSYEAKLRLLSSFDFFLTDARIRRLLPSLIG-RHFYQRKKVPVSVNLLSKN------LSREINDCIGGTVLNISKSGSCSAIRIGHVG-MQIEHIIENIVAVTKGLSEKLPEKWESVKLLFVKTEKS--AALPIFSSFVSNWDEATKRSLLNKKKKEARRKRRERNFEKQKERKKKRQQARKTASVLSKDDVAPESGDTTVKKPESKKEQTPEHGKKKRGRGKAQVKATNESEDEIPQLVPIGKKTPANEKVEIQKHATGKKSPAKSPNPSTPRGKKRKALPASETPKAAESETPGKSPEKKPKIKEEAVKEKSPSLGKKDARQTPKKPEAKFFTTPSKSVRKASHTPKKWPKKPKVPQST", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R8M8-1", "uniprot_id": "F1R8M8_DANRE", "id": "F1R8M8-1", "name": "Ribosomal L1 domain-containing protein 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLFLLFRHTCSMETPRDELTIDQSQVKKAAQALQAFIKNSTSSQKLFQN--------------------------------------------------------------------DGQPISLLFTLWKIPKK-EQTIRIPLS-------------HGLRTESGDVCLFTRDE---PNMTAEQTERFYKKLLTERGVKNVTEVIPFKALRTEYKPFEAKRKLLGNFDLFLSDARIRFRLPSQIG-KHFYERKKAPLSVDLESKH------LARDMERLIQGTTLTVSTKGPCCMARVAHSE-MTADQIVENVISAVSTISAKLASTGKNIKIIHLKSQTS--VALPIYTSDLS------HLALVEEAQKKAR---------LTKGAQKRKRK---------------------TENTEAPKPVTKETEEEK------------DSEEEIPQLVPIE--TPKKK--------------------TKREGLSKKGLKKVPKPAAGNSVKKSVK-----------------------DKKLVKK-------TPKRTERGLE------KKKLKTNKT-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLK2-1", "uniprot_id": "Y3096_DROME", "id": "Q9VLK2-1", "name": "Ribosomal L1 domain-containing protein CG13096", "aln": "MVKVQKPQPKSLNKSASIEGVVKKKGKPEKTKKLATDATLELASNKKAKNAAPVKKDAIKKEPEVSKKGAEKKQSKAAKRPLILAPPESPAAPAPAAKKSKAKPAASGAPVGKKIEAKKPLILAPPESPVPPKKQEKKTKAAPVKAKKEPAPAKKSVQDPVPSIKKVPAAKKSGQTAALTKKTAKTEKQAAPAKPAKAQPASQLQKKAKAVQKLSKPASPPKSKKALSKSKPGQAKGNAVNKEPAKSKKPVELTFELKAFDEKRFHEIVNENNVTKVCAALKSVVSEEVEKKKNTSIFSDYRYVLQVCSYKIPSCPKRMVKLNLK-------------HSLVGKDDDVALIVPDLQRGAKFDYDPTKQHYEDMLREAGVKQRLTVVPFNQLRNEMGSFEAKRKFLNSYDYLLCDGRLSGQATAFLG-KNTQKPRNVLHSLRLSKDNDK----LPQEVTRALTRTAFRQLSKGDLIAVPVGNHE-ITAEQLAENILLVIKQLQEVYPGGLANIRSMYLKIDITGTSALPLYVSMCAPPED--VPYVVGPREQRMLKLKKQANEVLSKFAMTKDAEF--------------------IKLTSDQVKRKAQLRKEK---------AALLAADAAPKDNDGGDAAVPAKKARKESSSEGAKADAESDEEEEVEEAEDSAGESGDEDEEGHDGDDTDE-----------------------DEDEDDDDDNEDGDDDEDEDDDEEDDDEEDDDDDDDEE--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38779-1", "uniprot_id": "CIC1_YEAST", "id": "P38779-1", "name": "Proteasome-interacting protein CIC1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAKKSNSKKSTPVSTPSKEKKKVIEKKSSTAIPRERVIKAVNELIKFTSKPQDENNEEGNNGKKNLLEDDEEE-------------------------------------------------------LKKDLQLIVVNNKSFTGTSKSFKLKLLNVKHSFYKPWKEASATAVKDFKVLLILKDS----DIKKVSEDDLFDQLDSEG--IKVDEIICGKDLKTVYKAYEARNAFISQFSLILADDSIVTSLPKLMGGKAYNKVETTPISIRTHANKEFSLTTLTNNIKKVYMNQLPVKLPRGTTLNVHLGNLEWLRPEEFVDNVELISEQLIKAY-----QIRSIFIKTNRS--PVLPLYYNQDVLDELEAKKDKIEETHEDDMVTIDGVQVHLSTFNKG-------------------------LMEIANPSELGSIFSKQIN------------------------------------------------------NAKKRSSSELEKESSESEAVKKAKS---------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: **.: : . .. . * . * . .:: * . .. .: *: * . . : .: : :: : *:. .:**: ::..:. :: * : . :* : : ... *: .: *..:: * :.: : :.: :*: . : .:: :.:* : : **:: . .: . :: . . .. . . ", "identical_positions": 19, "similar_positions": 90, "identity": "2.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130603-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5SXH7-5", "uniprot_id": "PKHS1_HUMAN", "id": "Q5SXH7-5", "name": "Pleckstrin homology domain-containing family S member 1", "aln": "MAG------GKQFTFSYENEVCKQDYFIKSPPSQLFSSVTSWKKRFFILSKAGEKSFSLSYYKDHHHR---GSIEIDQNSSVEVGISSQEKMQSVQKMFKCHPDEVMSIRTTNREYFLIGHDREKIKDWVSFMSSFRQDIKATQQNTEEELSLGNKRTLFYSSPLLGPSSTSEAVGSSSPRNGLQDKHLMEQSSPGFRQTHLQD----LSEATQDVKEENHYLTPRS--VLLELDNIIASSDSGESIETDGPDQVSGRIECHYEPMESY---FFKETSHESVDSSKEEPQTLPETQDGDLHLQEQGSGIDWCLSPADVEAQTTNDQKG--------------NIPDESQVEKLNVFLSPPDVINYLALTEATGRICVSQWEGPPRLGCIFCHGDHLLAVNDLKPQSLEEVSLFLTRSIQKEDSFRILSYQVAFGEGTELRDRAPGFRTSDRHDVAKRACMES-DWCRDSKTAPSTNLCLSFLFCKIMTNDGAGCWIIK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BW88-1", "uniprot_id": "PKHS1_MOUSE", "id": "Q8BW88-1", "name": "Pleckstrin homology domain-containing family S member 1", "aln": "MEARPPKGPGKQFTFDYENEVHKRDYFIKSPPPQLFFSGTSWKKRLFILSQSRGTGLSLSYYKDHQHR---GSIEIDGSSTVEVGINCQEKMQSVQKMFKCHPDEVMSIRTANRDYFLIGHDREKIKDWVSFMTPYCQGVKATHQRAEEKLSLGDRRPVSDPSPFLGLCSIPEGIRLASPRASLP-EHLIQKSLQRFRQAHLHQDHDFHSEPTQDT-EEEYYLTPRSLEACLELENIAGPNDSGDSIESNSPDQGFKRAESNYVSMRSLRTCLLKESTSASADDNDGQAEFQTESELGPPHQ-DSGTGSDPCLSPPNSKAQTTDDQKGSASLTVVKLSILLNNIPDESQVETLNVFLSPRDAIDYLALVEAAGQICVARWEGPPRLGCLFYHGDHILAVNDLKPQSLEEVSLFLTRCIQKEK----VKLSIGRIPNSEKLHASP-CACSLRHQLAESVQRDLPELERTPKRSPAIKKSQ---------KEAAGE----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "U3JA42-1", "uniprot_id": "U3JA42_DANRE", "id": "U3JA42-1", "name": "", "aln": "MADK-----NYTYYIHGAEEQLCSGYLYKSPPEKHLKNQKSWKRRYFVLLKYSNDRCLLNYYKNEEKNKSLGNIDLSKVTFMFLSPEMHAMWKWIHENFRCSPSSVMFMRVPEREYFLVGENSWEMEKWFNALFAILN---FRPHKLLDPKTFGSMRSISEP-----------------PQSEKDNEQGAQWGQTKYVPHELPS--------------------------VVAQEPIYDTPKKVKKLNSES-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : : :* .*: **** : : . .***:* *:* : *.***:..:. *.*::. : : :. . : : ::: *:* *..** :*..:*:***:*.: :::.*.. : . : :. : ::*. *.: . *: :: : . : .* . : : * . .. ..::::. ", "identical_positions": 36, "similar_positions": 82, "identity": "7.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130603-81", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P52191-1", "uniprot_id": "KCJ16_RAT", "id": "P52191-1", "name": "Inward rectifier potassium channel 16", "aln": "----------------------------------------------------------------------------------------------------------MSYYGSSYRIVNVDSKYPGYPP--EHAIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYMVDIFTTLVDTKWRHMFVVFSLSYILSWLIFGSIFWLIALHHG------------DLLSDPDITPCVDNVHSFTAAFLFSLETQTTIGYGYRCVTEECSVAVLTVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYSEDS-EGRMTMAFKDLKLVND----QIILVTPVTIVHEIDHESPLYALDRKAVA-KDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFHDVLEVKRKY--YKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLNNLEKTSPARGSCTSDTNTRRRSFSAVAMVSSCENPEETSLSP-QDECKEVPYQKALLTLNRISMESQM---------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z307-1", "uniprot_id": "KCJ16_MOUSE", "id": "Q9Z307-1", "name": "Inward rectifier potassium channel 16", "aln": "----------------------------------------------------------------------------------------------------------MSYYGSSYRIVNVDSKYPGYPP--EHAIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYMVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSIFWLIAFHHG------------DLLSDPDITPCVDNVHSFTAAFLFSLETQTTIGYGYRCVTEECSVAVLTVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYSEDS-EGRMTMAFKDLKLVND----QIILVTPVTIVHEIDHESPLYALDRKAVA-KDNFEILVTFIYTGDSTGTSHQSRSSYIPREILWGHRFHDVLEVKRKY--YKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLNNLEKTSPARGSCNSDTNTRRRSFSAVAVVSSCENPEETVLSP-QDECKEMPYQKALLTLNRISMESQM---------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPI9-1", "uniprot_id": "KCJ16_HUMAN", "id": "Q9NPI9-1", "name": "Inward rectifier potassium channel 16", "aln": "----------------------------------------------------------------------------------------------------------MSYYGSSYHIINADAKYPGYPP--EHIIAEKRRARRRLLHKDGSCNVYFKHIFGEWGSYVVDIFTTLVDTKWRHMFVIFSLSYILSWLIFGSVFWLIAFHHG------------DLLNDPDITPCVDNVHSFTGAFLFSLETQTTIGYGYRCVTEECSVAVLMVILQSILSCIINTFIIGAALAKMATARKRAQTIRFSYFALIGMRDGKLCLMWRIGDFRPNHVVEGTVRAQLLRYTEDS-EGRMTMAFKDLKLVND----QIILVTPVTIVHEIDHESPLYALDRKAVA-KDNFEILVTFIYTGDSTGTSHQSRSSYVPREILWGHRFNDVLEVKRKY--YKVNCLQFEGSVEVYAPFCSAKQLDWKDQQLH-IEKAPPVRESCTSDTKARRRSFSAVAIVSSCENPEETTTSA-THEYRETPYQKALLTLNRISVESQM---------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B7L6-1", "uniprot_id": "A0A8M3B7L6_DANRE", "id": "A0A8M3B7L6-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------MNSGKVQYSGVKSSDNIQSVVT--DDSCYSK---KKRYVRKDGSCNMVPRHVPEKWLLWVTDIFTTLVEIRWRVMLLTFALSYILSWLFFGILFWIIALTHG------------DMKN-PNNEPCVYEVRSFTAAFLFSLETQTTIGYGFRGMSENCMIAIIVVTIQDVISVFIDTFVIGIAVAKMASARKRAQTVGFSKCAVISIHDGHLCLSWRVGDFRRNHMVEGTSNAQLIEFQANNNTGKVDITYKDLIIEER----SVILATPTTIIHKILPGTPLYKMSLKDLR-KESFELVVSFTYTDDCTGILHQTRTSYTPSEILWGQNFQEMIRVTRKN--YRVDYALFNHTVKVLVPELSAEEYDLKKYSEQ--PKHKPLHISSPTP---------AVELVNGN-NLEAEKAST-SSAVQEHKL-------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KH86-1", "uniprot_id": "A0A0B4KH86_DROME", "id": "A0A0B4KH86-1", "name": "", "aln": "MPKMIVDKSELVGENAWAKLLPDEKDKAIIVKMNKSSSNNNDSKETTPLNVDQLVAASNPAVAGEQSAVCLEDTYKRTSTYASNINSTGGESSGSGTQLSRKESILGSFHRQIRRSIKAVSESPGPLTRYRQTRFSSRRVRKRVVFKHGECNVVQGNVAKRRRRYLQDIFTTLVDAQWRWTLLVFAASFVFSWAFFGFIWWIIAYAHNDLEYTNLKNQSPDLVANITHTVCVTQVSNMMSAFLYSVETQTTIGYGNRYVTEECPEAIFTMCIQCITGVFIQAFMVGIVFAKLSRPKKRAQTLLFSRNAVICHRDGVPCLMFRVGDMRKSHIIEAHVRAQIIRKKVTKEGEVLPFYQQELHIGADGGEDRLMFIWPTTIVHKIDRNSPLYMLSASDML-KERFEVVVMLEGVIESTGMTTQARSSYLPSEVLWGHRFVNVVSFRKETGEYEVDYTLFNNTYDVDTPLCSAKQLDELKSEYSKSAKCVNAPFADRTLSASLFQRIASAASVDHLDPASDESLDSGRLQIRSHSIPNGVLASELEPLNNNKHGASFTMGGLTITTTAPSIPNLSSINEKTNSGNSINSSNYSNNNSLSTLTGGGSAASGPGGGITIVAGSGNHGGAGGGGGGGGRHKSNPRRLSIKQDQLPIDSIC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7YZX2-1", "uniprot_id": "B7YZX2_DROME", "id": "B7YZX2-1", "name": "", "aln": "--------------------MQSDASPLGAAATDSLTMHRSTSMPVKPKPLEQKPLLR----SSEKETVNASDYYPESPGFVRRRRSKAAGDHLETRSEQNPTFSFPYAHDWAGSTIELTPDLGSGPR--TSSSDGLRRSLNRVMEKNGKENVVFRRIPEKSWRYMRDLVTTLMELEWKYMLTLFLGSYFLSWLLFAALCYVVAYSHG----DFIFDPVSGKRMGEGVDPCIYGVHSWVAMIIYSVETQTTLGFGEKYASEECPETIFLFVMQMLSAALIEGCMVSVIYAKTARPARQLTKLKFSDKAVICYRDGRLCLLFRVCDPREQQSIESKIRVYIIVDKRTR-EGETIKSHVELKLEGNG---EQIILWPDVVCHVIDETSPLSQFTTAKLFNAAQFELYVSIVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYDAQNERYIVDYENFNRTISVDMPMTNPKNDHLKLEYRK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . . .* : *.*. *: .: . :: *:.***:: .*: : * *:.:** :*. : :::* *. . *: * . . :::*:*****:*:* : :*:* ::: . :* : . :*: ::. ** : . :: .: ** *:* :** ** :*: * * .: :*. .. :: :* : :: * .: * * :** : : **: * : . .*. ::::** * *::**:.* ::: : * *: *: : .* * ..:: . ", "identical_positions": 66, "similar_positions": 109, "identity": "10.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130603-87", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AMC5-1", "uniprot_id": "A0A8I6AMC5_RAT", "id": "A0A8I6AMC5-1", "name": "", "aln": "VRSWRGSLVGRACCTGLTEPLPPGVAAALLPQFCLPPALLPSLPLPPAQARAEPAPEPEPEPERGHRGAGGGKAEVSGDPPPGSVPERPRTRTSAGAKGTRGLCRRAPASRLHGAQSEVSPGGERAHRRSSPANSTRSSLVSGTADAPGGVGPEPARAAGRPGDSFCCGTCGYRFCCHDGPRRLDQSRCSNYDTPAWVQTGRPPARARDTAAPRDPARERSHTAVYAVCGVAALLVLVGIGARLGLERAHSPRARRTVTRTLTELLKQPSPQEPLPPPLGPSLGNCVQVQMGDGVLRGSPHNSTDKKRLNNAPLGSATPGPPRGPR---------PQGGGSLTLQPDYAKFATLKAAALK--ATEAAPQDFYQRFPSTESGP----RTLPARVPRPPEDLPALLDACPWAPPGYVPPAGPVSSVPYAAWTAGRPARPLPRSHLVAQVSPAPRRPSHAPRRQFSVEKLPEAFSAQP----TSFYSSAGRGPRHLSTNSKAEVTV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "J3QNX5-1", "uniprot_id": "SHSA8_MOUSE", "id": "J3QNX5-1", "name": "Protein shisa-8", "aln": "--MERAGARGQRCGR---------------RSHGLPLALRLALLLAGSPSGRAGAPEEQ---------------EIAG------------SGTVAPAGGDR--CR-------------------------------------GYYDVMGQWDPPFNCSSG--VYSFCCGTCGYRFCCHDGPRRLDQSRCSNYDTPAWVQTGRPPARARDTAAPRDPARERSHTAVYAVCGVAALLVLVGIGARLGLERAHSPRARRTVTRTLTELLKQPGPQEPLPPPLGPPLGNCVQVQMGDGVLRGSPHNSTDKKRLNNAPLGSATPGPPRGPR---------LQGGGSLTLQPDYAKFATLKAAALK--ATEVAPQDFYQRFPSTETGP----RTLPARVPRPPEDLPALLDACPWAPPGYVPPAGPVSSVPYAAWTAGRPARPLPRSHLVAQVSPAPRRPNHAPRRQFSVEKLPEAFSAQQ----ASFYSSAGRGPRHLSTNSKAEVTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B8ZZ34-1", "uniprot_id": "SHSA8_HUMAN", "id": "B8ZZ34-1", "name": "Protein shisa-8", "aln": "--MARAGARGLLGGRRP-------------PGLRLALALRLALLLARPPSGRAGAPEAQGPAAPG---------------------------TTAPEGGDR--CR-------------------------------------GYYDVMGQWDPPFNCSSG--AYSFCCGTCGYRFCCHDGPRRLDQSRCSNYDTPAWVQTGRPPARARDTAAPRDPGRERSHTAVYAVCGVAALLVLAGIGARLGLERAHSPRARRTVTRALTELLKQPGPQEPLPPTLGPPLGGCVQVQMGDGLPRGSPHNSADKKRLNNAPRGSAAPGPPRGPR---------LQGGGSLTLQPDYAKYATFKAAALK--AAEAAPRDFCQRFPALEPSP----RQPPARAPRPSPDLPAPLDACPWAPPVYAPPAAPG---PYAAWTSSRPARPAPLSHPTARAFQVPRRPGHAARRQFSVK-MPETFNPQL----PGLYGSAGRGSRYLRTNSKTEVTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q3V9-1", "uniprot_id": "A0A8M9Q3V9_DANRE", "id": "A0A8M9Q3V9-1", "name": "", "aln": "MKILALKKQSMAG------------------NYFLLHLLLTAFLGRAAKAQDETSTDMDIQTANHTVDP--LMISVTSDGPPTLTTPGEVEEDTVPSTGTR--CR-------------------------------------GYYDVMGQWDPPFNCNAG--IFLYCCGTCFYRFCCQFRQQRLDQTSCSNYDTPIWANTGKP--VATNTEVQPDHERDRTHMIVYIICGVVAIMVLVGIFTKLGLEKSRGGQNDLSNSRTLQELMKQPGGE---ANAVDGPLSNSSSIGA-NGISARMLRSRSEQYHLNNAGFSFGALAGLSHPQSNLSIPGLALNKYNSLKAVADTANRSYYKSYPLMDFSQHHSPPVAFQPMPMHPKDKSYLHQVLPSHDIHSPLSISIPTNHMERTRIPKTITHPQLSSSAFKAWDSGR----RHVHRQTSHPGHLPRRQTYSSRRQYSIETIPDFLSQPTGYGGQPLYQHHPK-IKAYQTNSKTEVTV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * :: . : :.: : . * * ** * *. * .* :* :***** *****: :****: ******* *.:**:* * :* . * *:*:* ** :***.*::**.** ::****:::. : : :*:* **:***. : . .:. .*... .: :*: :. ::: :**** . .: . *: : .**. .* *: : *: .* : . :* * :* . : *:: :.. .:. : : . . .: ** :.* : .:: *** ::.***:*:: :*: :. :* : : ****:****", "identical_positions": 100, "similar_positions": 113, "identity": "19.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130613-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BFW4-1", "uniprot_id": "TRI65_MOUSE", "id": "Q8BFW4-1", "name": "E3 ubiquitin-protein ligase TRIM65", "aln": "MAAQLLEEDVVTCSICLGRYRDPVTLPCGHSFCGNCIQDSWRSCEK--SCPECRQPFPEGAKLSRNVKMSTLLQALP-VLPAPPAVTPRRDSATSHSARCLRHGRPLEFFCRTEGLCVCSACTVHDCSHHERALLDVERRVREDQLRARVLVTQQQVAQAETQLQELQEQRSRIESSACTLASVVSRRFSSLLQALEKQQASTLSDIEVAKKQALGQVLNEKQRLTDHLRALSQYDQSVQDLLAQADDCIFFQELQQLPEPTESLGPLTSPQWNEEQQLSNVNQLLSPLCELLLE--EKSLPKVAAKAADAGPLETLGPLAPVPSAVCP----LRKKLWQNYRNLTFDPETANQYLHLSHKDQRVTHHFQAQGPAKSGS---FELWQVQCTQSFQTGQHYWEVRVSDHSVTLGVTYPKLSRQKLGTHTDNIGRGPCSWGLCIQEDSMQAWHNGKSQRLRGLPG----QLLGVDLNLTSGCLTFYSLEPRTQPLHTFYAVFSQPLFPVFWLLEGRTLTLCHQPEATLPARPQEEATAPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PJ69-1", "uniprot_id": "TRI65_HUMAN", "id": "Q6PJ69-1", "name": "E3 ubiquitin-protein ligase TRIM65", "aln": "MAAQLLEEK-LTCAICLGLYQDPVTLPCGHNFCGACIRDWWDRCGK--ACPECREPFPDGAELRRNVALSGVLEVVR-AGPAR-DPGPDPGPGPDPAARCPRHGRPLELFCRTEGRCVCSVCTVRECRLHERALLDAERLKREAQLRASLEVTQQQATQAEGQLLELRKQSSQIQNSACILASWVSGKFSSLLQALEIQHTTALRSIEVAKTQALAQARDEEQRLRVHLEAVARHGCRIRELLEQVDEQTFLQE-SQLLQPPGPLGPLTPLQWDEDQQLGDLKQLLSRLCGLLLE--EGSHPGAPAKPVDLAPVEAPGPLAPVPSTVCP----LRRKLWQNYRNLTFDPVSANRHFYLSRQDQQVKHCRQSRGPGGPGS---FELWQVQCAQSFQAGHHYWEVRASDHSVTLGVSYPQLPRCRLGPHTDNIGRGPCSWGLCVQEDSLQAWHNGEAQRLPGVSG----RLLGMDLDLASGCLTFYSLEPQTQPLYTFHALFNQPLTPVFWLLEGRTLTLCHQPGAVFPLGPQEEVLS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WBJ0-1", "uniprot_id": "X1WBJ0_DANRE", "id": "X1WBJ0-1", "name": "", "aln": "------MEDHMQCTICLDQFKFPVTIPCGHTFCKTCISKFWDGREKDFQCPVCKECYETRPQLNRNVSMSVLTEVACTVSPVKSDVCRGAAFQTEPEQICERHQKPLVIYCRNDGMCVCYECSLNECKGHDKILVETEQRNREAGLKKKSAEIKKHQEATEQNRLELMENLEKEKVSLQQTSQWVNSKFSQLIKVLAEKQEVTQLFLEQQQELTVLQAEESLSVLEERTTRLSALQEEIDSLCLLPPCQLIKDS--RFMEVPRFAEVPVDVHAGVQEKLAPVTDVLSRVSKLVCEDLERAVQLSTGHQKDNSPQDKRPVLAVVPSPATPSYPAEREGLNAYHCALTFDPRTANAHLRLSQSNRRAEHLVSGPRPVPADESRFDHTWQVLCFQGFTSGQHYWELEVSKPWAYIGVTYPNIPRKQKG-KRCMVGMNDLSWSLQLDERQMSAWHAGCKETVAGQLDNTHPLRIGLLLDYEAGTLTYYGEG--QVRLHAFHCVFNQALFPACWIGEGVTVTLCEPRP---------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : *:***. :: ***:****.** ** . * * ** *:: : .:* *** :* : :. . *. .. * ** :** ::**.:* *** *::.:* *:: *::.*: ** *: ::: :* : ** :: .: : * :. *. :**.*::.* :: : :* : :: *. :. . * : :: : .* : :. :: : . . : . :::*. :.::** :. *: * * : ..: * .* : ** ***.. * *. * : ***** :** :: **:.:::. * .. * ... . *** * *.* :*:****:..*. . :**:**::.* : * : :* . **.* ::* .:.*** * : : * . :*: *: :* **:*. *::*:.:*.*.* *. *: ** *:***. ", "identical_positions": 133, "similar_positions": 161, "identity": "24.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130613-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P56522-1", "uniprot_id": "ADRO_RAT", "id": "P56522-1", "name": "NADPH:adrenodoxin oxidoreductase, mitochondrial", "aln": "MAPRCWRWWSWSAWPGVRPLPSRSTPTPGFCKKFSTQETTPQICVVGSGPAGFYTAQHLL-KHHTRAHVDIYEKQLVPFGLVRFGVAPDHPEVKNVINTFTQTARSD--------RCAFRGNVVVGRDVSVPELREAYHAVVLSYGAEDHQPLEIPGEE-LPGVVSARAFVGWYNGLPENQK--LAPDLSC---DTAVILGQGNVALDVARILLT--PPEHLEKTDITEVALGVLRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLP--GTQPILDPSDFLGLQDRIKDVPRPRKRLTELLLRTATEKPGVEEAARRALA------SRAWGLRFFRSPQQVLPTPDGRRVAGIRLAVTRLEGVGESTRAVPTGDVEDLPCGLLLSSVGYKSRPIDPSVPFDP--KLGIIPNTEGRVVN-------APGLYCSGWVKRGPTGVITTTMTDSFLTSQVLLKDLKAGLLPSGP-RPGYTAIQALLSDRGVRPVSFSDWEKLDAEEVARGQGTGKPREKLVDRREMLQLLGH-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61578-1", "uniprot_id": "ADRO_MOUSE", "id": "Q61578-1", "name": "NADPH:adrenodoxin oxidoreductase, mitochondrial", "aln": "MAPRCWHWWRWSAWSGLRPSPSRSTPTPGFCQKFSTQEKTPQICVVGSGPAGFYTAQHLL-KHHTHAHVDIYEKQLVPFGLVRFGVAPDHPEVKNVINTFTQTARSD--------RCAFQGNVVVGRDVSVPELREAYHAVVLSYGAEDHQPLGIPGEE-LPGVVSARAFVGWYNGLPENQE--LAPDLSC---DTAVILGQGNVALDVARILLT--PPEHLEKTDITEAALGALRQSRVKTVWIVGRRGPLQVAFTIKELREMIQLP--GTRPILDPSDFLGLQDRIKDVPRPRRRLTELLLRTATEKPGVEEAARQALA------SRAWGLRFFRSPQQVLPTPDGQRVAGIRLAVTSLEGVGESTRAVPTGDVEDLPCGLLLSSVGYKSRPIDPSVPFDP--KLGVIPNTEGRVVN-------VPGLYCSGWVKRGPTGVITTTMTDSFLTSQALLEDLKAGLLPSGP-RPGYVAIQALLSNRGVRPVSFSDWEKLDAEEVSRGQGTGKPREKLVDRREMLRLLGH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22570-1", "uniprot_id": "ADRO_HUMAN", "id": "P22570-1", "name": "NADPH:adrenodoxin oxidoreductase, mitochondrial", "aln": "MASRCWRWWGWSAWPRTRLPPAGSTPS--FCHHFSTQEKTPQICVVGSGPAGFYTAQHLL-KHP-QAHVDIYEKQPVPFGLVRFGVAPDHPEVKNVINTFTQTAHSG--------RCAFWGNVEVGRDVTVPELREAYHAVVLSYGAEDHRALEIPGEE-LPGVCSARAFVGWYNGLPENQE--LEPDLSC---DTAVILGQGNVALDVARILLT--PPEHLERTDITKAALGVLRQSRVKTVWLVGRRGPLQVAFTIKELREMIQLP--GARPILDPVDFLGLQDKIKEVPRPRKRLTELLLRTATEKPGPAEAARQASA------SRAWGLRFFRSPQQVLPSPDGRRAAGVRLAVTRLEGVDEATRAVPTGDMEDLPCGLVLSSIGYKSRPVDPSVPFDS--KLGVIPNVEGRVMD-------VPGLYCSGWVKRGPTGVIATTMTDSFLTGQMLLQDLKAGLLPSGP-RPGYAAIQALLSSRGVRPVSFSDWEKLDAEEVARGQGTGKPREKLVDPQEMLRLLGH-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FB58-1", "uniprot_id": "E7FB58_DANRE", "id": "E7FB58-1", "name": "NADPH:adrenodoxin oxidoreductase, mitochondrial", "aln": "MKMMMNIMKGSLMKIHTLSRASRCLLADGGVRGLSS--VSARVCVVGGGPAGFYTAQQLL-KARQDAVVDIYERLPVPFGLVRFGVAPDHPEVKNVINTFTQTAQHE--------RCSFHGNVNVGKDVTIEELRQAYHAVVLSYGAEGNRSMGIPGED-LCNVFSAKDFVGWYNGVPSNTE--LCPDLSC---ETAVVLGQGNVALDVARILLS--PVDMLKETDITQNALEALTGSNVRRVLIVGRRGPLQIACTIKELREMVNLP--NTRADMLPADFEGIAEALKELPRPRKRLTDLMMKAVKE-------GGDEKL------EKSWGFRFFRSPVEVLAGVDGKKAAGVRLALNKLEGEGEGARSVPTGQLEDVDCGLIISSIGYKSLPIEPTVPFDP--RKAIVPNDMGRVQD-------AEGLYCSGWVKRGPTGVIATTMNDSFDTARVIIQDMETGKLDVSVNKPGAEAITGLLQTRGVRMVLFSEWEKINAEEERRGKALGKPREKLLDVEKMLKIAWS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3T9-1", "uniprot_id": "ADRO_DROME", "id": "Q9V3T9-1", "name": "NADPH:adrenodoxin oxidoreductase, mitochondrial", "aln": "MGINCLNIFRR----GLHTSSAR-------LQVIQSTTPTKRICIVGAGPAGFYAAQLIL-KQLDNCVVDVVEKLPVPFGLVRFGVAPDHPEVKNVINTFTKTAEHP--------RLRYFGNISLGTDVSLRELRDRYHAVLLTYGADQDRQLELENEQ-LDNVISARKFVAWYNGLPGAEN--LAPDLSG---RDVTIVGQGNVAVDVARMLLS--PLDALKTTDTTEYALEALSCSQVERVHLVGRRGPLQAAFTIKELREMLKLP--NVDTRWRTEDFSGIDMQLDKLQRPRKRLTELMLKSLKE-------QGRISG------SKQFLPIFLRAPKAIAPG-------EMEFSVTELQQEA----AVPTSSTERLPSHLILRSIGYKSSCVDTGINFDT--RRGRVHNINGRILKDDATGEVDPGLYVAGWLGTGPTGVIVTTMNGAFAVAKTICDDINTNALDTSSVKPGYDAD-------GKRVVTWDGWQRINDFESAAGKAKGKPREKIVSIEEMLRVAGV-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48360-1", "uniprot_id": "ADRO_YEAST", "id": "P48360-1", "name": "Probable NADPH:adrenodoxin oxidoreductase, mitochondrial", "aln": "-------------------------MSFVQIRHISSQINRKTVSIVGSGPSGFYTAYHLLKKSPIPLNVTIWEKLPVPFGLSRYGVAPDHPEVKNCEETFTTCAEEFSSPTNQKHKFSFVGGITIGKEILLKELLDNQDAVILSYGCTGDRKLNIPGELGTKGVFSSREFVNWYNGHPDFAKDKRFTDFDWSKVSKVGIIGNGNVALDITRVLISNQIDEIWENTDISSLALNLLRRAPVKDVKLIARRDFVHSKFTNKELRELWELEKYGIRGRIDPKFFQKEMFDPSKYDRAFNRRVEMCSEYLKPFNERSKKNYKKAPPPSSGYDKFWELDYLKTPLKINRDDFG-AINSLSLCNNRLNEDNSLQPLKDVNNIMTYKVDLLITSLGYAGVPMPEFSKLSIGFDKDHIANKQGRVLTS--SGEIFPHLYASGWIRKGSQGVIASTMQDAFEVGDRVIQDLVV---------SGALSLENSIDLSNIKHTTWKDWERINKKELLRGKKEHKTRSKFLTFEELWNGVEGI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.: :.:**.**:***:* :* * * : *: ***** *:*********** :*** *. : : *.: :* :: : ** : .**:*:**. .: : : .* .* *:: ** **** * : .*:. . ::*:****:*::*:*:: : : ** :. ** * : *. * ::.**. :: * *****: :* . . * .. *. .* .:: . . .: : ::::* : : :. . *: ... *:: *:** . : :. : * **: ** :**: *. ***.:** .:* .. : .*: . .* : . : . :. *:::: * *: *.*.*:: .:: . ", "identical_positions": 108, "similar_positions": 134, "identity": "20.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130613-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66H07-1", "uniprot_id": "FANK1_RAT", "id": "Q66H07-1", "name": "Fibronectin type 3 and ankyrin repeat domains 1 protein", "aln": "-----------------------MEPKKIVPL-----------------LRPHPPVVGKVTHHSIELYWDLEKREKRQGPQEQWLRFSIEEEDPKMHNYGVIYTGYATKHVVEGLEPRTLYRFRLKVTSPSGEYEYSPVVSVATTREPISSEHFHRAVNVNDEDLLLRILEGGHVMVDVPNKFGFTALMVAAQKGYTRLVKILISNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRKHGASWDARDLGGCTALHWAADGGHCPVIDWMIKDGCEVDVVDTGSGWTPLMRVSAVTGSQKVASLLIEAGADVNVRDKDGKTPLMVAVLNNHEQLVQLLLDKGADATVKNEFGKGVLEMARVFDRQNVLSLLEERKKK-MPRKSSVH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DAM9-1", "uniprot_id": "FANK1_MOUSE", "id": "Q9DAM9-1", "name": "Fibronectin type 3 and ankyrin repeat domains 1 protein", "aln": "-----------------------MEPHKVVPL-----------------SKPHPPVVGKVTHHSIELYWDLEQKEKRQGPQEQWLRFSIEEEDPKMHSYGVIYTGYATRHVVEGLEPRTLYKFRLKVTSPSGEYEYSPVVSVATTREPISSEHFHRAVSVNDEDLLLRILEGGHVMIDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGASWEARDLGGCTALHWAADGGHCSVIDWMIKDGCEVDVVDTGSGWTPLMRVSAVTGSQKVASLLIEAGADVNIKDKDGKTPLMVAVLNNHEQLVQLLLDKGADATVKNEFGKGVLEMARVFDRQNVLSLLEEKKKK-MPRKSSVH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TC84-1", "uniprot_id": "FANK1_HUMAN", "id": "Q8TC84-1", "name": "Fibronectin type 3 and ankyrin repeat domains protein 1", "aln": "-----------------------MEPQKIMPP-----------------SKPHPPVVGKVTHHSIELYWDLEKKAKRQGPQEQWFRFSIEEEDPKMHTYGIIYTGYATKHVVEGLEPRTLYRFRLKVTSPSGECEYSPLVSVSTTREPISSEHLHRAVSVNDEDLLVRILQGGRVKVDVPNKFGFTALMVAAQKGYTRLVKILVSNGTDVNLKNGSGKDSLMLACYAGHLDVVKYLRRHGASWQARDLGGCTALHWAADGGHCSVIEWMIKDGCEVDVVDTGSGWTPLMRVSAVSGNQRVASLLIDAGANVNVKDRNGKTPLMVAVLNNHEELVQLLLDKGADASVKNEFGKGVLEMARVFDRQSVVSLLEERKKKQRPKKSCVC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6P4-1", "uniprot_id": "A0ACD6B6P4_DANRE", "id": "A0ACD6B6P4-1", "name": "", "aln": "MSPMYLGLMQLKLCCYSNNIQLFIQALKTLKIPLTILGFLLSMDPAEKRHRSEALAVGQVSHHSIELVWSREKGSKWTDPPQNWTCFILEQMNNTKHSFKQIHKGYNTRFTVDNLEPKTTYTFRLKVTWPSGQQQYYPSVTASTEKPPLNGKNLHSAVLKTDEVELCRVLQSGTVTVDVPDRLDYTPLMMAAIKGFTSGVQILVHHGADVSRKNSSGKDSLMLACFHGHLDVVKLLCGCGASWRARDRTGCCSLHWATAGGQLDILQYLIQYGCEVNVQDN-IAWTPLMIVSVITGDPAVASLLISAGADVNVQDRDGKTPLMVAVLNNYEHLVQILLKKGADPNIQNKCGVSALEMAKAFDRQNIISLLEDEESE-RPK-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. * : :... .**:*:****** *. *: * .* ::* * :*: : . *.: *:.** *:..*:.***:* * ****** ***: :* * *:.:* : *:..:::* ** .** * *:*:.* * :***:::.:*.**:** **:* *:**: :*:**. **.**********: ******* * **** *** ** :****: **: :::::*: ****:* *. .***** **.::*. ******.***:**::*::************:*.***:**.****..::*: * ..****:.****.::****:.:.: *: ", "identical_positions": 168, "similar_positions": 106, "identity": "43.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130613-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZGJ0-1", "uniprot_id": "D3ZGJ0_RAT", "id": "D3ZGJ0-1", "name": "Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32", "aln": "-----------MSSLREEMDEEELEHPNASPEKRYFPESLDSSDGDEEGVLAC-------------EDLELNPFDGLPYSSRYYKLLKEREELPIWKEKYSFMESLLQNQVVLVSGDSKCGKSSQVPQWCAEYCLSIHYQHGGVICTQVHKQTAVQLALRVADEMDVNIGHEVGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIINCSPFLISRLSSYYGNVPLLEVRN-KHPVEVVYLSGAQKDPFESVVRLIFEIHRSGEQGDVVVFLACEQDIEKTYEIVCQEGSNLN--PDVGELVVIPLYPKEKCSLFRPVDE-TEKRCQASQRRVVLTTSCGESLIWS-HTVRFVIDVGLERRQVYNPRIRANSLVLQPISQSQAEIRKQLLGSSPSGKLFCLYTEEFASKDMRPLKPAEMQEANLTSMVLFMKRVDIAGLGRCDFMNRPAPESLMQALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEMLTIAAMVTAPSCFLHVPHGAEEAAVTCWKTFLHPEGDHFTLINIYNAYQDTVLNSANEHCVETWCHNCFLSCSALRMADVIRAELLEIIKRIELPYAEPAFGSQENGLNIKKALLSGYFMQIARDVDGSGNYLMLTHKQVAQLHPLSSYAITKK---MPEWVLFHQFSISENNYIRVTSAVSPELFMQLVPQYY-FSNLPPSESKDILQQAS--GHL-PTTAMDKDQDVCDKCPDATEQRCTVQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZS9-1", "uniprot_id": "DHX32_MOUSE", "id": "Q8BZS9-1", "name": "Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32", "aln": "------------------MDEEELDHPNASPEKRYFPESLDSSDGDEEGVLAC-------------EDLELNPFDGLPYSSRYYKLLKEREELPIWKEKYSFMESLLQNQVVVVSGDSKCGKSSQVPQWCAEYCLSIHYQHGGVICTQAHKQTAVQLALRVADEMDVNIGHEVGYVIPFENCCTTETILRYCTDDMLQREMMSNPFLGSYGVIILDDVHERSLATDVLLGLLKDVLLARPELKLIVNCSPLLTSKLSSYYGDVPVIEVRN-KHPVEVVYLSGAQKDSFESVIRLIFEIHRSGEKGDVVVFLACEQDIEKTYELVCQEGSNLN--PDVGDLVVIPLYPKEKCSLFRPVDE-TEKRCQVYQRRVVLTTSCGESLIWS-HTVKFVIDVGLERRQVYNPRIRANSLVLQPISQSQAEIRKQLLGSSPSGKLFCLYTEEFASKDMRPLKPAEMQEANLTSMVLFMKRVDIAGLGRCDFMNRPAPESLMQALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEMLTIAAMVTAPSCFLHVPHGAEEAAVTCWKTFLHPEGDHFTLINVYNAYQDTVLNSANEHCVEMWCHDCFLSCSALRMADVIRAELLEIIKRIELPYAEPAFGSKENGLNIKKALLSGYFMQIARDVDGSGNYLMLTHKQVAQLHPLSSYSITKK---MPEWVLFHQFSISENNYIRVASAVSPELFMQLVPQYY-FSNLPPSESKDILQQAA--GHL-PTETVNKDQDVCDKCPDATEQRCTIQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L7V1-1", "uniprot_id": "DHX32_HUMAN", "id": "Q7L7V1-1", "name": "Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32", "aln": "------------------MEEEGLECPNSSSEKRYFPESLDSSDGDEEEVLAC-------------EDLELNPFDGLPYSSRYYKLLKEREDLPIWKEKYSFMENLLQNQIVIVSGDAKCGKSAQVPQWCAEYCLSIHYQHGGVICTQVHKQTVVQLALRVADEMDVNIGHEVGYVIPFENCCTNETILRYCTDDMLQREMMSNPFLGSYGVIILDDIHERSIATDVLLGLLKDVLLARPELKLIINSSPHLISKLNSYYGNVPVIEVKN-KHPVEVVYLSEAQKDSFESILRLIFEIHHSGEKGDIVVFLACEQDIEKVCETVYQ-GSNLN--PDLGELVVVPLYPKEKCSLFKPLDE-TEKRCQVYQRRVVLTTSSGEFLIWS-NSVRFVIDVGVERRKVYNPRIRANSLVMQPISQSQAEIRKQILGSSSSGKFFCLYTEEFASKDMTPLKPAEMQEANLTSMVLFMKRIDIAGLGHCDFMNRPAPESLMQALEDLDYLAALDNDGNLSEFGIIMSEFPLDPQLSKSILASCEFDCVDEVLTIAAMVTAPNCFSHVPHGAEEAALTCWKTFLHPEGDHFTLISIYKAYQDTTLNSSSEYCVEKWCRDYFLNCSALRMADVIRAELLEIIKRIELPYAEPAFGSKENTLNIKKALLSGYFMQIARDVDGSGNYLMLTHKQVAQLHPLSGYSITKK---MPEWVLFHKFSISENNYIRITSEISPELFMQLVPQYY-FSNLPPSESKDILQQVV--DHLSPVSTMNKEQQMCETCP-ETEQRCTLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NYY8-1", "uniprot_id": "A0A8M1NYY8_DANRE", "id": "A0A8M1NYY8-1", "name": "Putative pre-mRNA-splicing factor ATP-dependent RNA helicase DHX32", "aln": "-----------------------------MAGNGELSGELGKEEEDSENLFEFG------------DDLELNQFDGLPYSSRYYRLLQERKTLPVWKYRHEFMTLLENNQILIVSGTTKTGKSTQIPQWCAEFCLSAQYQHGVVVCSQIQRRQAVDLALRVADEMDVNIGHEIGYSIPLETCCSNDTILRYCTDDILLREMMSDPLLEQYGVVLVDQAHERTVSTDVLLGLLREVLLQRPELRLVVLSAPPTPETLLTHYGSVPRLHLEA-PSAGEVIHSSSSSSESFYSALRLALEVHRSREPGDVAVFLATEQEVVCACNIITKEASRMS--VSLGELLAVPMCSG-HAGICPPVTE-SPQ----MSRRIFVSCSQLEDLFWSVDSIAFVIDTGVEKRLVYNPRLRASSEVIRPISKCQAEMRKQLTGS--TGKCFCLYPEDVQ---LPAEIHPRILESNITSTALFLKRMEAAGVTHCHFINRPDPEGLMQALEELDYLAALDNDGNLSEMGIIMSELPLEPQMAKALLASCEFDCASEMLTIAAMLTAPSCFIEPPVGMLTEVMRCHMKFQHPEGDHFTLINIYNTFKRSQREP--YFSQEQWCEQYYLCCAALQTADAIRSQLSDVLKRIELPISEPAFGTKTNALNIKRALLAGYFMQMARDVDGSGNYFMLLNKHVAQAHRLSAYGAKAQKLGLPEWLLFHEYSLTDN-SIRTLTHISPHAFVQMAPQYF-FCNLPPSESKEILQNILDRDRTGIPKAKTRPEPKTETQESEAQERCVLQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53131-1", "uniprot_id": "PRP43_YEAST", "id": "P53131-1", "name": "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43", "aln": "MGSKRRFSSEHPDPVETSIPEQAAEIAEELSKQHPLPSEEPLVHHDAGEFKGLQRHHTSAEEAQKLEDGKINPFTGREFTPKYVDILKIRRELPVHAQRDEFLKLYQNNQIMVFVGETGSGKTTQIPQFVLFDEMP-HLENTQVACTQPRRVAAMSVAQRVAEEMDVKLGEEVGYSIRFENKTSNKTILKYMTDGMLLREAMEDHDLSRYSCIILDEAHERTLATDILMGLLKQVVKRRPDLKIIIMSATLDAEKFQRYFNDAPLLAVPGRTYPVELYYTPEFQRDYLDSAIRTVLQIHATEEAGDILLFLTGEDEIEDAVRKISLEGDQLVREEGCGPLSVYPLYGSLPPHQQQRIFEPAPESHNGRPGRKVVISTNIAETSLTIDGIVYVVDPGFSKQKVYNPRIRVESLLVSPISKASAQQRAGRAGRTRPGKCFRLYTEEAFQKELIEQSYPEILRSNLSSTVLELKKLGIDDLVHFDFMDPPAPETMMRALEELNYLACLDDEGNLTPLGRLASQFPLDPMLAVMLIGSFEFQCSQEILTIVAMLSVPNVFIRPTK-DKKRADDAKNIFAHPDGDHITLLNVYHAFKS---DEAYEYGIHKWCRDHYLNYRSLSAADNIRSQLERLMNRYNLELNTTDYESPKYFDNIRKALASGFFMQVAKKRSGAKGYITVKDNQDVLIHPSTVLGHDAE------WVIYNEFVLTSKNYIRTVTSVRPEWLIEIAPAYYDLSNFQKGDVKLSLERIK--EKVDRLNELKQGKNKKKSKHSKK-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :. . . * . :* ::* * * ::.:* :*: *. **: : .*: :**:::. * : **::*:**: :. : :: * *:* :: .:.:* ***:****::*.*:** * :*. :..***:* **.:* ** *.: * *. :::*: ***:::**:*:***::*: **:*:::: .:. . : ::...* : : . *: : . . : : * :* :::* : * **: :**: *::: . . : ...: . * * . *: : * : : * .: : : . : :*:* *..:: *****:*..* :: ***:..*: * * .** * **.*: : ..: .:*::* .* :*:: .: : .*:: * ** :*:***:*:***.**::***: :* : *::**:* :: ::.* **:* .*:***.**::.*. * . . . . * **:***:**:.:*:::: : . . **.: :* :* ** **::* :::* :* . : : **::** :*:***:*:. .*: .*: : .:: . * : . : *:::::: ::.: ** : : *. ::::.* *: :.*: .: * *:. : : : .. ", "identical_positions": 179, "similar_positions": 266, "identity": "22.74%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130618-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G5Q1-1", "uniprot_id": "A0A8I6G5Q1_RAT", "id": "A0A8I6G5Q1-1", "name": "Semaphorin-4D", "aln": "-----------------------MKMCAPVRGLFLALVAVWRTAVAFAPVPRITWEHGEVGLVKFHEPGIFNYSSLLMSEDKDTLYVGAREAVFAVNALDISEKQHEVYWKVSEDKKSKCAEKGKSKQTECLNYIRVLQPLSSTSLYVCGTNAFQPTCDHLNLTSFKFLGKSEDGKGRCPFDPAHSYTSVMVGGELYSGTSYNFLGSEPIISRNS-SHSPLRTEYAIPWLNEPSFVFADVIHKSPDGTEAEDDKVYFFFTEVSVEYEFVFKLMIPRVARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNILQDVFVLRAPGLKEPVFYAVFTPQLNNVGLSAVCAYTLSTVEAVFSRGKYMQSATVEQSHTKWVRYNGPVPTPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPKLIKKDVNYTQIVVDRTQALDGTFYDVMFLSTDRGALHKAVILAKEVHVVEETQLFQDFEPVLSLLLSSKKGRKFVYAGSNSGVVQAPLAFCGKHSSCEDCVLARDPYCAWSPAIKACVTLHQAEGSSRGWIQDMSGDTSSCLDKS---KESFHQHFFKHGGTAELKCFQKSNLARVVWKFQNGELKAVSPKYGFVGRKHLLIFNLSDGDSGVYQCLSEERVRNKTVSQLLAKHILEVKMVARIPPSPTSQTAQT-EGSRITSKMPVASTQGSSPPTPALWATSPRAATLPPKSSSTGTSCEPKMVINTVPQLHSEKTVYLKSSDNRLLMSLLLFLFVLFLCLFSYNCYKGYLPGQCLKFRSALLLAKKKPKSEFSDLEQSVKETLVEPGSFSQQNGDQPKPAL-DTGYETEQDTITSKVPTDREDSQRIDELSARDKPFDVKCE---LKFADSDADGD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O09126-1", "uniprot_id": "SEM4D_MOUSE", "id": "O09126-1", "name": "Semaphorin-4D", "aln": "-----------------------MRMCAPVRGLFLALVVVLRTAVAFAPVPRLTWEHGEVGLVQFHKPGIFNYSALLMSEDKDTLYVGAREAVFAVNALNISEKQHEVYWKVSEDKKSKCAEKGKSKQTECLNYIRVLQPLSSTSLYVCGTNAFQPTCDHLNLTSFKFLGKSEDGKGRCPFDPAHSYTSVMVGGELYSGTSYNFLGSEPIISRNS-SHSPLRTEYAIPWLNEPSFVFADVIQKSPDGPEGEDDKVYFFFTEVSVEYEFVFKLMIPRVARVCKGDQGGLRTLQKKWTSFLKARLICSKPDSGLVFNILQDVFVLRAPGLKEPVFYAVFTPQLNNVGLSAVCAYTLATVEAVFSRGKYMQSATVEQSHTKWVRYNGPVPTPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPKLIKKDVNYTQIVVDRTQALDGTFYDVMFISTDRGALHKAVILTKEVHVIEETQLFRDSEPVLTLLLSSKKGRKFVYAGSNSGVVQAPLAFCEKHGSCEDCVLARDPYCAWSPAIKACVTLHQEEASSRGWIQDMSGDTSSCLDKS---KESFNQHFFKHGGTAELKCFQKSNLARVVWKFQNGELKAASPKYGFVGRKHLLIFNLSDGDSGVYQCLSEERVRNKTVSQLLAKHVLEVKMVPRTPPSPTSEDAQT-EGSKITSKMPVASTQGSSPPTPALWATSPRAATLPPKSSS-GTSCEPKMVINTVPQLHSEKTVYLKSSDNRLLMSLLLFIFVLFLCLFSYNCYKGYLPGQCLKFRSALLLGKKTPKSDFSDLEQSVKETLVEPGSFSQQNGDHPKPAL-DTGYETEQDTITSKVPTDREDSQRIDELSARDKPFDVKCE---LKFADSDADGD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92854-1", "uniprot_id": "SEM4D_HUMAN", "id": "Q92854-1", "name": "Semaphorin-4D", "aln": "-----------------------MRMCTPIRGLLMALAVMFGTAMAFAPIPRITWEHREVHLVQFHEPDIYNYSALLLSEDKDTLYIGAREAVFAVNALNISEKQHEVYWKVSEDKKAKCAEKGKSKQTECLNYIRVLQPLSATSLYVCGTNAFQPACDHLNLTSFKFLGKNEDGKGRCPFDPAHSYTSVMVDGELYSGTSYNFLGSEPIISRNS-SHSPLRTEYAIPWLNEPSFVFADVIRKSPDSPDGEDDRVYFFFTEVSVEYEFVFRVLIPRIARVCKGDQGGLRTLQKKWTSFLKARLICSRPDSGLVFNVLRDVFVLRSPGLKVPVFYALFTPQLNNVGLSAVCAYNLSTAEEVFSHGKYMQSTTVEQSHTKWVRYNGPVPKPRPGACIDSEARAANYTSSLNLPDKTLQFVKDHPLMDDSVTPIDNRPRLIKKDVNYTQIVVDRTQALDGTVYDVMFVSTDRGALHKAISLEHAVHIIEETQLFQDFEPVQTLLLSSKKGNRFVYAGSNSGVVQAPLAFCGKHGTCEDCVLARDPYCAWSPPTATCVALHQTESPSRGLIQEMSGDASVCPDKS---KGSYRQHFFKHGGTAELKCSQKSNLARVFWKFQNGVLKAESPKYGLMGRKNLLIFNLSEGDSGVYQCLSEERVKNKTVFQVVAKHVLEVKVVPKPVVAPTLSVVQT-EGSRIATKVLVASTQGSSPPTPAVQATSSGAITLPPKPAPTGTSCEPKIVINTVPQLHSEKTMYLKSSDNRLLMSLFLFFFVLFLCLFFYNCYKGYLPRQCLKFRSALLIGKKKPKSDFCDREQSLKETLVEPGSFSQQNGEHPKPAL-DTGYETEQDTITSKVPTDREDSQRIDDLSARDKPFDVKCE---LKFADSDADGD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PCY2-1", "uniprot_id": "A0A8M9PCY2_DANRE", "id": "A0A8M9PCY2-1", "name": "", "aln": "MNQFSPLDAMAFKGNLTLPKVPESNMALSVLGVFLGLLLEVSTHGPSS-VPRSSWKQDDVDLLEFWEPDVFNYTTLLLNEDRGVLYVGAREAVYELNISNISIKNNQLLWKVPDSDMSMCILKGKSKETDCRNYIRVLQVLDEEHLYVCGTHAFQPLCDYLSLQDFRLLEKAEDGRGKCSYDPAQSFTTVMVDGELYSGTAYNFLGSEPIISRSSPSQSLLRTEYSTSWLNEPSFVFADVIREGQDSPDGDDDKIYYFFTEVSVEYEFFGKLLIPRIARVCKGDLGGQRTLQKKWTSFLKAKLVCSMPELNFVFNVVHDVFILKAPHWRDTVIYGVFTSQWGNVGLSAVCAYNMSSVHEVFSRGKYMQKVTVEQSHTKWVRFNGAPPSPRPGACINNMNRQQNMSSSLHLPDKTLQFVRDHPLLEDPVLPIGNGPRLITKDVNYTQIAVQRVQALDNSIHHVIFTATDKGFLHKSVVLENEVHTVEEVQLLKNSEPIKTLLLSTDQAQ-FLYAGSDSGVVQSPTAFCQKYGSCVDCVLARDPYCAWYTQSKACVNIFQSKADPRKMIQNLKGDAGICPPVSPLAVKDYPLLLVKPGASADLPCRVQSNRAQVLWKLNNQLLSDSSSRLLLMSESGLLLYSVTMEDAGRYECWSVESAAGQNFSRVVSGYILRLDLPESKSAQLTREPTTTSEGNSVNNNNSPVTPGLTSAPTDAPSLTTPPTSAIKPKSNIPPEVSNSPARTETIDP----SAKYIQHDNSAALLALFLLFFLLFLAALLYNCYMQYLPAPCLRLRSALLGSSKKPQAEYAACEAG----LMEKTDPANQIAAHPLRALRDTGYETEPEAELGNGAVR---SNSFDESPCKDRPFDIDCASQPIEFADADADAP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*. .: *:::.* * . : :** :*:: :* *::* :*.::**::**:.**:..**:******: :* :** *:::: ***.:.. : * *****:*:* ******* *. ******:**** **:*.* .*::* * ***:*:*.:***:*:*:***.*******:************.* *:* *****: .*************::. *..:.:**::*:***********. :::***:******* ** *************:*:** *: .:***:::***:*::* : .*:*.:**.* .**********.:::.. ***:*****..***********:**. *.*******:. * * :***:*********:****::*.* **.* *:**.********.*:*.****.:.:.*:* :**:* ***:: * : ** :**.**::: **: :****:.:.. *:****:*****:* *** *:.:* ************ . :** :.* :. .* **::.**:. * * .: :.* *.:*:* * :** *:*.**::* *. *.: ::... **::.:: *:* *:* * * . .:.. :::: ::*.:.: * . . * **. : .: .:. :*.** * *:. : :: **. .:. :*: .: *:: .:. *::*:*::*:***. : **** *** **::***** ..*.*::::. * . *:* . ::* . :* ** ******* :: .: .. *: :*: ..:*:***:.* ::***:***. ", "identical_positions": 399, "similar_positions": 279, "identity": "44.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130620-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2A7Y5-1", "uniprot_id": "MIIP_MOUSE", "id": "A2A7Y5-1", "name": "Migration and invasion-inhibitory protein", "aln": "MPNMAETKDPVRLRLLSLELLKQLWAGHEAMCRSVVRAASGSNLDCSS-NNLEMPLSQETSSASSVAPSSQDKRHMLDPLDSRRDDTFDVAWYVKFNSRMDSFLPATGQHQEPQEELRPPSVPLLATQGLKGPVSLGGPKGLGPDKTQVPRSILSRLSKPSKPRVT-SQESAVPESSWHSRPYLGYDWIAGSLDNSSPVTSEPEAFFSMLQRFRENNKEDCVCNSPE--AVFPGLQESSG-------VEEDHECMYCYRINRRLFPEPVDPGAPCRLCGIPRDEKGPGTLVEPVQVRVSIPLSIMDPPHQYRIHRRKSFDASDTLALPRHCLLGWDILPPKSEKTSVPKSLDLWSSVSYGAGQRRDLS---ATSPPCQALPAQVTP--PLWSEPQVAQLCPSH----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JXC2-1", "uniprot_id": "MIIP_HUMAN", "id": "Q5JXC2-1", "name": "Migration and invasion-inhibitory protein", "aln": "---MVEAEELAQLRLLNLELLRQLWVGQDAVRRSVARAASESSLESSSSYNSETPSTPETSSTSLSTSCPRGRSSVWGPPDACRGDLRDVAR-----SGVASLPPAKCQHQESLGRPRPHSAPSLGTSSLRDPEPSGRLGDPGPQEAQTPRSILAQQSKLSKPRVTFSEESAVPKRSWRLRPYLGYDWIAGSLDTSSSITSQPEAFFSKLQEFRETNKEECICSHPE--PQLPGLRESSGSG-----VEEDHECVYCYRVNRRLFPVPVDPGTPCRLCRTPRDQQGPGTLAQPAHVRVSIPLSILEPPHRYHIHRRKSFDASDTLALPRHCLLGWDIFPPKSEKSSAPRNLDLWSSVSAEAQHQKLSG---TSSPFHPASPMQMLPPTPTWSVPQVPRPHVPRQKP-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GU07-1", "uniprot_id": "A0AC58GU07_DANRE", "id": "A0AC58GU07-1", "name": "", "aln": "---MAALEELDALRKKNRDLLEKLKKQSEKLHQMIISDSQEVDRNLSSVCEGFTLNRAPLKEKNGEQPPRASASTARKTIQICDEQLPADFEN------RTLDLHKLTHSQSSEATAYGTLLQDTGNSRWTGQCRTVRLMLPKSADLTADSDILREADRASTAGLQMETTSDR-----RMQPLLGYDWIAGLLDAESSLADRSEQFFSDLRSFRQVNRDECIHSLLSGLPSVADLASSTLDSEEVRPPADSHQCTFCYRVNSRLFAVPLDAQAACPVCKKPKSE-HPHTETEPALIRVSIPRSTLLPAHKYKAHRRSSFDPSDSLGLPSHCLSGWSN--PMLTSGSQMISLDLRSSMTKPAATGDSTSSCFHNKPIRLAFDVTLLSLPTRSNISHRSQSMTLLQHCSSSHDVSIYLSHRHLYSAVLSAFFFFTHQLS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. :: ** . :**.:* : : : : :. . : ** : .. . . . . : : : *.. ... . . . . .** . .: *.. : . * : :* ******** ** .*.::...* *** *: **: *:::*: . . . ...* .*: :.*:* :***:* ***. *:*. :.* :* *:.: * * .:*. :***** * : *.*:*: ***.***.**:*.** *** **. * . * .*** **:: * . ..* * : . . . .: .: ", "identical_positions": 88, "similar_positions": 107, "identity": "20.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130625-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K045-1", "uniprot_id": "A0A0G2K045_RAT", "id": "A0A0G2K045-1", "name": "", "aln": "MRSHPSLLLVYMGLATCLDTLPHREQSQVLDIFLDAPEAQSFLVGRRRFPRANHWDLELLTPGNLERECLEERCSWEEAREYFEDNTLTERFWESYAYNGKGGRGRVDVAGLAVGLTSGILLIVLAG-LGAFWYLHYRRRRLRVQESCLQ-ETGLIIPLS------PPTPLSPPPPP--GLPTYEQALAASGVHDAPPPPYS--SLRRPH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R182-1", "uniprot_id": "TMG2_MOUSE", "id": "Q8R182-1", "name": "Transmembrane gamma-carboxyglutamic acid protein 2", "aln": "MRGRPSLLLVYMGLATCLDTSPHREQNQVLDIFLDAPEAQSFLVGRRRFPRANHWDLELLTPGNLERECLEERCSWEEAREYFEDNTLTERFWESYTYNGKGGRGRVDVAGLAVGLTSGILLIVLAG-LGAFWYLHYRRRRLRGQESCLQ-ETGLIIPLS------PQTPQSPPLPP--GLPTYEQALAASGVHDAPPPPYS--SLRRPH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14669-1", "uniprot_id": "TMG2_HUMAN", "id": "O14669-1", "name": "Transmembrane gamma-carboxyglutamic acid protein 2", "aln": "MRGHPSLLLLYMALTTCLDTSPSEETDQ--EVFLGPPEAQSFLSSHTRIPRANHWDLELLTPGNLERECLEERCSWEEAREYFEDNTLTERFWESYIYNGKGGRGRVDVASLAVGLTGGILLIVLAG-LGAFWYLRWRQH--RGQQPCPQ-EAGLISPLSPLNPLGPPTPLPPPPPPPPGLPTYEQALAASGVHDAPPPPYT--SLRRPH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WF92-1", "uniprot_id": "X1WF92_DANRE", "id": "X1WF92-1", "name": "", "aln": "MLG---FSVICLSLLSLLHLVWGRVIYNENDVFLEEKSAGSFLS---RKLLYNSWDFEAVVPGNLERECIEEICSYEEAREVFEDDKKTAAFWKDYVNS-HQKLTEVDVAGLSAGIVAAVLVVVIATVLGVYCYKNRGKNARGGSVPVQMGEDGRPVPES--------VPLSGIVPA--GLPSYNEALTHSGQHDAPPPPYSGTTPTAPP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : :: :.* : *. . : ::** .* *** * * **:* :.********:** **:***** ***:. * **:.* . : .****.*:.*:...:*::*:* **.: * . :. . . * * * * .* . *. ***:*::**: ** ********: : * ", "identical_positions": 73, "similar_positions": 52, "identity": "34.76%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130625-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ULL5-3", "uniprot_id": "PRR12_HUMAN", "id": "Q9ULL5-3", "name": "Proline-rich protein 12", "aln": "MDRNYPSAGFGDPLGAGAGWSYERSAKASLVYGSSRTSHPETDILHRQAYAAPHPLQSYATNHHP--------------AGLSGLFDTGLHHAGSAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFP-VPSSLSLQDPP-FSPPANGLLSPHD-VLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYN---FSGAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPAHALQHYLSCGGS----YPSMGHRANLACSPLGGGEPSPGAGEPSKA-----------------GPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAG-------------------GATRPPPP-----------RSTATPKCQSLGGPAAAYATG-KASGAGGAGGQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKAPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQGEPYPGPAAHSQGLPTASPSLSYS---TGHSPALSGHGGGWG--------PSSLGGGG-----------EASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAG--------SYAAGAGGYKGKGDGSELLAGPGGPPAERTEDEEFLIQHLLQAPSP-PRTSGADGLVGEDGAADASKGLGGS-GGAGGPPGTPYELAKEDPQRYHLQSVIRT-------------SASLDEGATAALELGLGRLKEKKKGPERGGETPEG------------------LATSVVHYGAGAKELGAFLQKSPPPPPP---TAQSTQPTPHGL------LLEAGGP-DLP-------------------LVLPPPPPQ------LLPSVLSHAPS---------------------------------------PSPSASKVGVHLLEP-----ATRDGAPQPPPPPPPPPPPMPLQLEAHLRSHGLEPAAPSPRLRPEE----------------------SLDPPGAMQELLGALEPLPPAPG----------------------------------DTGVGPPNSEGKDPAG---------------AYRSPSPQGTKAP----------RFVPLTSICFPDSLLQDEERSFFPTMEEMFG-----------GGAADDYGKAGPPEDEGDPKAGAGPPP-----------GPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQS-GP-------HQAAPPPPPPPPPPPAPASEP-KGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPP--FQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLP----DLVSSCRSRPALSPLG-------DIDFCPPN------PGP-----DGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVPTTAGPASASTPTDGAKKPRGRGRGRGRKAEEAGGTR-------------------------------------------------------------------------LEPLKPLKIKLSVP------------------------------KAGEGLGTSSGDAISGTDHNSLDSSLTREKIEAKIKEVE--------------------------EKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPPSVPARGLQPQPPATPAVPHPPPSGAFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEP-------PLLEEKPPPTP------------------------------------------------------------------------------------PPAPTPQPQPPPPPPPP-QPALPSPPPLVAPTPSSPPPPP---------------------LPPPPPPAMPSPPPPPP-------PAAAPLAAPPEEPAAPSPEDPELPDTRP------LHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPVPVRRSGQAKNPVSAGGSSAP----------------------------PPKAPAPPPKPETPEKTTSEKPPEQTPETAMPEPPAPEKP---------------------------SLLRPVEKEKEKEKVTRGE-----RPLRGERATSGRQTRPERSLATGQPATSR--------LPKARPTKVKAEPPPKKRKKWLKEAGGNATAGGGPPGSSSDSESSPGAPSEDERAVPGRLLKTRAMREMYRSYVEMLVSTALDPDMIQALEDTHDELYLPPMRKIDGLLNEHKKKVLKRLSLSPALQDALHTFPQLQVEQSGEGSPEEGAVRLRPAGEPYNRKTLSKLKRSVVRAQEFKVELEKSGYYTLYHSLHHYKYHTFLRCRDQTLAIEGGA-EDLGQEEVVQQCMRNQPWLEQLFDSFSDLLAQAQAHSRCG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9PYL2-1", "uniprot_id": "PRR12_MOUSE", "id": "E9PYL2-1", "name": "Proline-rich protein 12", "aln": "MDRNYPSAGFGDPLGAGAGWSYERSAKASLVYGSSRTSHPETDILHRQAYAAPHPLQSYATNHHP--------------AGLSGLFDTGLHHAGSAGPDASVMNLISALESRGPQPGPSASSLLSQFRSPSWQTAMHTPGPTELFISGALPGSSTFPSSSALSAYQHPASFGSRPFP-VPSSLSLQDPP-FSPPANGLLSPHD-VLHLKPSQAPTVPSSLGFERLAGGGVLGPAGLGPAQTPPYRPGPPDPPPPPRHLPTQFNLLASS-SAATAAEPSSPQLYN---FSGAAPGPPP-ERALPRQDTVIKHYQRPASAQPPPPPPPAHSLQHYLSCGGS----YPSMGHRASLACSPLGGGEPSPGAGEPSKG-----------------GPSGATAGAAGRATGPETAGGG-AAGGGGGYRPIIQSPGYKTSKGGYGPATG-------------------GATRPPPP-----------RSTATPKCQSLGGPAAAYAAG-KASGAGGAGSQAYSPGQPQGLLGPQAYGQGFGGGQAQDLSKGPSYSGGPPQPPSGPPPPGLATCQSYSPDQLQGQLYGVQSEPYPGPAAHSQGLPTASPSLSYS---TGHSPALSGHGGGWG--------PSSLGGGG-----------EASPSHIIRPLQSPPATGRPPGVGSPGAPGKYLSSVLASAPFLAPPGAS--------SYAAGAGGYKGKGDGSELLAGPGGSAAERTEDEEFLIQHLLQAPSP-PRTSGADGLVGEDGPADAAKGLGGS-GGAGGAPGTPYELAKEDPQRYHLQSVIRT-------------SASLDEGATAALELGLGRMKDKKKGPERGGETPEG------------------LATSVVHYGAGAKELGAFLQKSPPPPPP---SAQATQPAPHGL------LLEAGGP-DLP-------------------MVLPPPPPQ------LLPSVLSHAPS---------------------------------------PSPSAPKVGVHLLEP-----ATRDGAPQPPPPPPPP---MPLQLEAHLRGHGLEPTAPSPRLRPEE----------------------SLEPPGAMQELLGALEPLPSGPG----------------------------------DPGVGPPNSEGKDPAG---------------AYRSPSPQGTKAP----------RFVPLTSICFPDSLLQDEERSFFPTMEEMFG-----------GGAADDYGKAGQTEDDGDPKTGAGPPP-----------GPTAYDPYGPYCGGRASGTGPETPGLGLDHNKPPELPSTVNAEPLGLIQS-GP-------HQSAPPPPPPPPPPP-PVSEP-KGGLTSPIFCSTKPKKLLKTSSFHLLRRRDPP--FQTPKKLYAQEYEFEADEDKADVPADIRLNPRRLP----DLVSSCRSRPALSPLG-------DIDFCPPN------PGP-----DGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEGPAMAGPASITT--DGAKKPRGRGRGRGRKAEEMGGTR-------------------------------------------------------------------------LEPLKPLKIKLSVP------------------------------KAGEGLGAPSNDVISGVDHNSLDSNLTREKIEAKIKEVE--------------------------EKQPEMKSGFMASFLDFLKSGKRHPPLYQAGLTPPLSPPKSVPASVPTRGLQPPPPTVPTVPHPAPSGPFGLGGALEAAESEGLGLGCPSPCKRLDEELKRNLETLPSFSSDEEDSVAKNRDLQESISSAISALDDPPLTGPKDTSTPEEPPLDTGPTASGPPPLPSLPSSNSSGTPEP-------PLLEEKPPPTP------------------------------------------------------------------------------------PPAPTPQPAPPPPPPPPPVPALPSPTPLVTPVASSPPPPP---------------------PPPPPPPALPSPPPPPPPA-----PTTVPPVAPPEEPPAPSPEDPEPPDARP------LHLAKKQETAAVCGETDEEAGESGGEGIFRERDEFVIRAEDIPSLKLALQTGREPPPIWRVQKALLQKFTPEIKDGQRQFCATSNYLGYFGDAKNRYQRLYVKFLENVNKKDYVRVCARKPWHRPPLPVRRSGQTKGPTPVGGNSAP----------------------------PSKVQAPPPKPETPEKMTSEKPPEPAPEPAVPEPPAPEKP---------------------------SPPRPVEKEKEKEKEKEKEKERVTRPLRSERATSGRQMRTDRSLATGQSTTSR--------LPKARPSKVKAEPPPKKRKKWLKEAVGNASAGDGPGGSSSDSESSPGAPSEDERAVPGRLLKTRAMREMYRSYVEMLVSTALDPDMIQALEDTHDELYLPPMRKIDGLLNEHKKKVLKRLSLSPALQDALHTFPQLQVEQTGEGSPEEGAVRLRPAGEPYNRKTLSKLKRSVVRAQEFKVELEKSGYYTLYHSLHHYKYHTFLRCRDQTLAIEGGA-EDLGQEEVVQQCMRNQPWLEQLFDSFSDLLAQAQAHSRCG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "X1WDQ3-1", "uniprot_id": "X1WDQ3_DANRE", "id": "X1WDQ3-1", "name": "", "aln": "MDRNYPGTGFGD-LGAGTGWSYERSAKASLVYGSSRSSHPDSELLHRQPYATPHPLQGYATNHHPGTSGQGGAWGAGRSLGLSGLFDTGLHHASPSGPDASVMNLISALESRGAQPPPSASSLLSQFRTPSWQTAMHTPAPAELFISGALPGSGSFPSSSALSAYQHPASFSGRSFPGVAPSLSLQDTPTFSPTSNGLLSPHDPLLHIKTPSQ----SSLGFDRLLSSQSGNASYRGPQEPTSAPPPQASASSSSRHLPPQFNLLSSQ------LQDQSSQLYNSSVFSSAPPQPQSQERAIPRQDSVIKHYQRPSPGQSQLSSSTPHPLQHYLSCGASGYQQIPHHRHGSAINCSPLGEQSPSSDPKPSPRSEQIYRPIIQPPYTTSSVSSSASSGGGIGKTGKSSSSSSGYSSSGSSSSRTPHTPPSASSTTSSSSSASNPNASSSTSSAPSRQQPPPQSAPQPPPPPPPTVSSSVTQQQPPKPCLSTYGSPVAPVKPTPGLPGQTPPQQQSYSPSQPPPSHLPQPYG-GFSSPQAQDLGSSLGGSG-KAYGSLGTTGRSFSAEVVYGSDSGYGSLPPSLGG--AGSPSMSYGGTGHSPALMVSGGGTGTTGSTTGSGAGSSGSVGVGSVSGSVGSGAGSYHLPDSSPSPSSNSGIIRPSLHSPVPTRPAQSPGGNGGSKYLSSVLSPAFLASPQGYSDSRVPPQQTQSYHTTPPKSKSD-SDMLGVERSQEEDEEDEEDFLIQQLLHSQSPGPNSSQHHSQQAQQVASQQPQPQSISQSRDGGKSLSAYELNKASEERYHLQSVIRTNNTTNSASTVTAGSCGQGTGLENQLEMSLKKQQQTKADRVLSGAGTNGGRGAIDSLSHAHSHGQHDSLSSVVHYGRGDHYTHQTHQHHPTHPSHSQHPQHSQHPHPHSMSHSHMDLKKAQDPSELPYLRKTPDLQQRQTQSTIGLMDSPPDPSQQTSQAHLLQSVLSHTTRNKMDNQQASTQQQQQHPMSQQAMIGQTGGLGNSGPGGVDTQPQASQLQLQLQSQTMEVHYGREAQRNQSQSSQNSVSPLDMLERSLSRTNSREGTAPSDRVGTGDGSNADHHRQQQHRMSSHHQSHHSQQPAAELHDFLSEPDVSMSAPSHLHHMTSHHPPPHAHHQPQTHSHHHNPHQHPHHMQPSSGPPQPQSQTREQEPQLSQPQLDQLKEHQYDTGSPVGKTSQNQNQTQEQQQRFVPLTSICFPDSLLQDEDRSFFPGMEDMFCSEDYKASCAGGGGSAGQGGQDGVSEARGSVPDGMDVVKNTGGGGAYDMMGHHGDQGYGQYCHS-LSESGNGTMHLDLDPLKSHELPSTVNTEQLGLIQSQGPGLGMGSTGQVMDGTGNKMMGNVGVGSGPGTGGLSSPIFCSSRPKKLLKTSSFHLLKQRKDPNAQSQVKKNYAQEYEFEDDEDKANVPADIRLNSRRLPDLLPDLVSSCRKSGSGSGVGSLSPLISDLDFCHPSGYPSLRPPPQMLPQDGPKKRGRKPTKPKREGPPRPRGRPRIRPLPEPPYCRNMLGPG--GESRRGRGRGRGRGRKDDQMLDMHRDMNKGQNYHQQAPQLHHQPQLQQHMHHHLQQQQQQHQPQHMHQQQHLHVQQQLHHQQQHHQQLAQHQPQQQYQEPIKPIKIKLPIPSMPSSDSLLRTDSMSSTDPVLSDGSVGSAPSLGLSPGPTNSVELNRIDMNRNDMGCGQEKMKQKAQEQMSWEGDMDDQMTPEAWATMQKLSSSTDEKSSELKSGFITSFLDFLKTGKKP-----GTEAPPVDGCTSTDSSSIKGGIRPLSPQPP----PPPPPHFGEN---EGDGSLGLSN-CPSPCKRLDEELKRNLETLPSFSSDEEDSVSKNQDLQKSISSAISALYDTPHSLAAIPPPPTPSPPTPQTVSLNTPPPPSDPESILHVHAEPEPDIHASQQLETHTRPNPQEEAHIPGEDEEQEEPVQETHDEIQQKDDTQSECEEEGDELEEDRSEKDGADPIRTEESKQEEEEEEEDEPAYEMLDALKAAERSPLESPPAPPSPPSLSPSPPTSSSPSPLPPPPLSLPSPLPSQEEEENIQQQPQQPPLHNSLPPSPSPPALPSPSPPPPTLPPSATPPPSPSPPPPEELPQPSPESPPTPEDAPTPQITSLHLAKKQSNAAIAGESEDDDSESGGEGIFRERDEFVVRTEDIGALKLALQTGREPPPIWRVQKALLQKFAPEIKDGQRQFCATSNYLGYFGDAKMRYQRLYVKFLENVNKKDYVRVCSRKPWHRPSLTLRRQSLPK-PQPVRSLTPPRMERDDREKERERQREKEQREQREKEKEREREKEREREREQIEKSRREKEKEKERERELEKQKEREKQKEREKEKEREKQREREREKEKQREKERERERQREKEREKQREKEKEKEREKEKKLQQRQTQEKLDRRPALVERGRVKEDKKVGEKRADRTRSRPVKVKAEPPPKKRKKWLKEVP-----------SSSDSDSSPEPPSDDEVSTR-SGMNSRAMREMFRSYVEMLVSTALDPDMIQALEDTNDELYLPPMRKIDSILNEQKRRLLRRLNISVQHQEALHMFPQMTADP-----LDSGAVKVHLGGEGYNRKTLNRVKRSLPKQQDLKLSTETCRKYSLYHSLHHYKYHTFLHCKKETDSIEQAAEEDPGQEEVVQQCMANQGWLETLFNSFIELLTLSTKA----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******.:**** ****:******************:***::::****.**:*****.******* *************..:*****************.** ***********:**********.*:***********.:****************..*.** *..******.* ***.:******** :**:*... *****:** .. ..: ** :... * .......****.*****:*. : .*.**** **.*.* * . ***:****:********:..*. .....*.********.* * * : : ***** .**... ..:. ..*.::.*. *:: ..::..* :..*... *. .*. .: ... ..*:. .*.:**** :....* .: *.*.*. . .* . *:***.** **.** **.. *****... . ** . . *.. .::: *..*. *.* . .*..: * * . **:* * ** : : :* *.* . ..*:*.*. :* * **** .*.. **. . .. .*******:.* : :* * . : : : *.*.* *::*. . :. ::*:****:**:: ** *.:* .. .:: .:: .: . * . ** . :.*** * . :********** *.. . * **:.* : ::.* . .* .:* :****** * : *: *. *. . :: :* **.: * :* .* :** : ** *.* ** *****:. ..*.*.:: ::* . *:. : . .. . : : .: * :. * :*** *: . : * :*.. ::::*. : ..*. :.. ***:.:.: * : ** *..: ******************:***** **:** **:*.: *: * .* *. * . * . : ** ** . * :* * *.** *. *******:* ****** ** * . * * .***:******::*************::*. * . ** ******** *****:********.**** *******. : * :* *:*** *. * * ***::*******.**:************** *. . . . ::: ********** :: . : **:**:****.:* . * . *.... :. * * * . :**:: * :* **..*:****::*******:**: . :**:. .*. .* *::* .* * *.*. ** . *. * **. ******************************:**:***:********* *.* : . ...* .* . .. ..** *. *.: .** ** :. *.* .* :* . *.**. .* *: .**.** .* * *.* * *.*.***:***.**** *.. * .**** . ****.* *: * *******..**:.**:::: .***************:*:*** :*************************:************************ **********************:*******.:.:**.. .* * .. . :.* : : * ** ** * * : : ** . * ***:**:: .. * . :* *. : * : *: .: .::** *****************. *****:*** .**:** :. :::******:***********************:************.:***:*:::*:**.:* *:*** ***: .: :.***::: .** ******.::***: : *::*:. *.. *:**************:*:.:* :** .* ** ********** ** *** **:** :**: : ", "identical_positions": 990, "similar_positions": 528, "identity": "36.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130723-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AM63-1", "uniprot_id": "A0A8I6AM63_RAT", "id": "A0A8I6AM63-1", "name": "Synaptotagmin-like protein 2", "aln": "MIDLSFLTEEEQDAILKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHKDKIHGADIIRASMRRKRLPAAAEQKKDTAMRTKESWVNNVNKDASLPPELA-VVEEPADDTGPAGPSSSVVDPASSAIERS--------QENTRTPAVSLPKQRKNPFDSLETPEDLSSQQTKTKQSKTGKAGLFQIS----KEGGLSESKEKPSIPDMSCQKSEKPKQPVSMETENASLIKAPIPKARKLIYKSNDLKNDDYLSFAGQRRDSLNARGTPRGILKRNSSSSSTDSETLRLNYNLDPKSKILSPG---------LTIHERISEKEHSLDDDSCTNSLEPLKHVRFSAVKNDLPQSPRPVLGQEVGEFTVLESDRLQNGTEDTGDIDEFQDHPEFS-HRKPLSLYQSVTNPRISERETEQPMSSGSIPSE-----EISCHSDILPTRPQCVESSSIIS-EQDKSSHFTKLQSEMSKSPEDELTQCVEP-----EPSQTSDHSFRDHRQGKPLLTALTDQTASPVGPCATEIRKTTDDSISKVLDWFNRSSHTEDSTSTLQHLQGLDLREQTDSRAQISNTLMTDNMSLKGDDTKVPASTTTKVKPVRPDSTFQEEGDVLASESCRDSDALLKSNSEDLSQQGTLKKGPDTLQRFERYRIPSHKNENMGDSQGSESTGEGVGTLPADSDYLLRPLKRSDSEEAPWNTTHPSSLGKGKTKFHVPQKSKRNTHINADSSVIFLDSILKDDAERKSKTRNISFLKPSLETENSGLPPGATDSGSSWRKPEDQEEVGEEPKNQVLREKYKRVSDRISFWEGGKAGAKLKAPQPASSCSQESSSTKAYQPVKSQVMSLGSLSLGQSDYSQVTAKHGVFDGDDQTPRLASSSSSNKPETTGSPISGLSKNHPSGNQFGKVTLPQTMENETHPSLEKDRFLIDKSNGNFKVLSLRERMDERNTEHVYSHSQFENLRKFWGLGADGNSKHSDGNNTATNKQTSVPSNRQKSKEFNTVNLSSEKTPEVEEGRHLRQGNVGAAEEMEKLNLKCRLPAPPDETKFPQKTPQKFTYPLVGNEPSKEDVGKNTECLVTPVTEKACSDQEIQESIVKTSVLPKVSTDTFKDRVQKLVAEATSPAGQTSGKEVHEQQALKVGASENGAWPQNKSFVKDEEELTGVKKSTKELQRRIPQDCSVDKLLKEATGTPSSPLQSLQEPVMTRPSSPPKEDLLFKKWIRENHSPSADQRERTAPSPQGVETLAGTDFTSKAKHCNTEGMLQLTAEGSPPLAQPSQSFEGVSSPPADVSLSWNAPLLSQDSTLSSQREISEAIEKVVLPSKPAMTDINAVLQKLLREAGEVDTKLPERPLSPQRVSSVWAAPDPVGPNEDSHSSYPVPDTTHEGRSARMAPSAHATTSPTYTVTRYGQELLQEVAETVRETIIQPKPECPEFRAALEKLRKETLQTSLSKDDKNTVTISPSALTGSCETSHQLAFEFHPTEIQETVEKAEAPSVTESIFDVGLEKLLKEMSEGPRQLQLTRDILEKQTSQAEQAGLMGETPHPFLDDSGASKMNFASSGLESQVSPCDKQLGGDEAVTGQLIDVQGYAGGFGVSECPQPYEDHKREDVETVLFVEDKGREKVIAEATRAPQKPGFEEAPKEMRVSRNKRSIVLLETKGKATETSTVKSELATAYKRQEKEQGPEACSESEFSDGNTSSNRESWRNTSSSEEEHSPVLKTLERRAARKIPS-KSLEDIPSDSSNQAKVDNLPEELVRSAEDDQKADQDPDTNECIPGISTVPSLPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLRRYKKSPSSLTNLSSSSGMTSLSSASGSVMSVYSGDFGNLEVKGSVQFAIDYVESLKELHVFVAQCKDLAAADAKKQRSDPYVKTYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIERQVLKTQKLNLSVWHRDTFKRNSFLGEVELDLETWDWDSKQNKQLKWYP---LKRKTAPVALETENRGEMKLALQYVPEPSPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTSNPVFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEAALWEKMVNSPNTWVEAMLPLRMLLIAKISK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N50-1", "uniprot_id": "SYTL2_MOUSE", "id": "Q99N50-1", "name": "Synaptotagmin-like protein 2", "aln": "MIDLSFLTEEEQDAILKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHRDKIHGADIIRASMRRKKLPAAAEQNKDTAMRAKESWVNNVNKDAVLPPEIA-VVEEPEDDTDPAGPSSSLVDPASSVIDMS--------QESTRTPAVSLPKQRKNPFNSPKLPEDHSLQQTKPEQSKTGKAGLFQIS----KEGELSESKEKSSIPDMPRQQLEKPKQTVSTEPENASHTKAPIPKARKLIYKSNDLEKDDNQSFPRQRRDSLNARGAPRGILKRNSSSSSTDSETLRLNYNLDPKSKILSPG---------LTIHERISEKEFSLEDDSSTSSLEPLKHVRFSAVKNELPQSPRPVLGQEVGEFTVLESDQLQNGTEDAGDIEEFQNHPELS-HKTPLSHYQLVSSPSDSGREREQLMSSGSAPRD-----EIPCHSDILPTGPQCVESSSVINGQQEKSSHFTKLPSELSKSPSDELTQCGEP-----EPSQTADHSFRDHRQG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEEEHSPVLKTLERRAARKLPS-KSLEDIPSDSSNQAKVDNLPEELVRSAEDDQKADQEPDTNECIPGISTVPSLPDNQFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLRRYKKSPSSLTNLSSSSGMTSLSSASGSVMSVYSGDFGNLEVKGSVQFALDYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKTYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIERQFLKTQKLNLSVWHRDTFKRNSFLGEVELDLETWDWDSKQNKQLKWYP---LKRKTAPVALETENRGEMKLALQYVPEPSPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPVFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWVEATLPLRMLLIAKLSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCH5-1", "uniprot_id": "SYTL2_HUMAN", "id": "Q9HCH5-1", "name": "Synaptotagmin-like protein 2", "aln": "MIDLSFLTEEEQEAIMKVLQRDAALKRAEEERVRHLPEKIKDDQQLKNMSGQWFYEAKAKRHRDKIHGADIIRASMRKKRPQIAAEQSKDRENGAKESWVNNVNKDAFLPPELAGVVEEPEEDAAPASPSSSVVNPASSVIDMS--------QENTRKPNVS-PEKRKNPFNSSKLPEGHSSQQTKNEQSKNGRTGLFQTS----KEDELSESKEKSTVADTSIQKLEKSKQTLPG-LSNGSQIKAPIPKARKMIYKSTDLNKDDNQSFPRQRTDSLKARGAPRGILKRNSSSSSTDSETLRYNHNFEPKSKIVSPG---------LTIHERISEKEHSLEDNSSPNSLEPLKHVRFSAVKDELPQSPGLIHGREVGEFSVLESDRLKNGMEDAGDTEEFQSDPKPSQYRKPSLFHQSTSSPYVSKSETHQPMTSGSFPIN-----GLHSHSEVLTARPQSMENSPTINEPKDKSSELTRLESVLPRSPADELSHCVEP-----EPSQVPGGSSRDRQQG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEEEPSPVLKTLERSAARKMPS-KSLEDISSDSSNQAKVDNQPEELVRSAED----------------VSTVPTQPDNPFSHPDKLKRMSKSVPAFLQDESDDRETDTASESSYQLSRHKKSPSSLTNLSSSSGMTSLSSVSGSVMSVYSGDFGNLEVKGNIQFAIEYVESLKELHVFVAQCKDLAAADVKKQRSDPYVKAYLLPDKGKMGKKKTLVVKKTLNPVYNEILRYKIEKQILKTQKLNLSIWHRDTFKRNSFLGEVELDLETWDWDNKQNKQLRWYP---LKRKTAPVALEAENRGEMKLALQYVPEPVPGKKLPTTGEVHIWVKECLDLPLLRGSHLNSFVKCTILPDTSRKSRQKTRAVGKTTNPIFNHTMVYDGFRPEDLMEACVELTVWDHYKLTNQFLGGLRIGFGTGKSYGTEVDWMDSTSEEVALWEKMVNSPNTWIEATLPLRMLLIAKISK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B6D8-1", "uniprot_id": "A0A8M3B6D8_DANRE", "id": "A0A8M3B6D8-1", "name": "", "aln": "MIDLSHLTEDEQEMILEVLKRDAELKKSDEQRIKQLRKTERDRGRLKYLTGEWFYETKYHRHRDRIHGSDIIRASMKRKPVTLLEITQRWSE---KPSSVYGPKRDVYIPPELSGLIEDPQSHNDRVDDESQQETQRPQVKPRQNPFNIFRLQRDEVKPINAVKEAKQTPAEEPFLPVESYTLHHTTLNTDNTDTHIITLKPVPKKRLLLYSSKDSSLDTANSDNGVKQVVNPAPRGILKHNGSSYSSTDSLRLHIPSNDGSSSGQSSATVSPISLETPISPPLSPCSLHSASGWLDRKQVRFSSIIGPIERVQGEHSLLEEDWSPLSDQERSCIIENGHHEPQSSQVSNIHTSTEEAGKTTELSTEVKTDKVTVEEDRSILKVFDWFGKGSRDGKLKELPTKKELN-EEEPKPDESLVTKSDDSEAPDVHLKTTKPVPKPRRGLFAMFSRAENKDKNPEVQASEKAKCETEANDNILEQISFPTENRMAEILQDENKPDKLCEEPSQQERFDQDEVSTGRLVNLKSFWERGDRGPKILSMKKEDEEEESETSQLNENYHNTTQSDMLSDSSTSLSKPKLSDPEPADVESTLIGSSLISPRRTSNGVAISLLEDEEPFILDNHKASENSSSKLHTLVEYNALDSDQQEESICRDISDLKKEISTLKISISQHEDKVSINDLKSFWEKEKGGLRVIVSSQTCTANVKDPSPEPSPNRSLGRLSEPQFDIRSNNPSSPDRRIFKEFNLIEQKLKMEKVEDKQRSENTVPLQDLQDIRGRVPHIMQNLSNIEQFIADPHSSPSPPSSPLRSLSPKGQHDKPHYADIYQPKDRDQTRTPSPLRQFKVPCRDSYPSKESTKDGSPLKTFPIDINPANTSSCSVRLKPGQTSMYTSPEHRRKTSDGGSDTRSILTK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ERKLSLDSLTRFYIPLSLHHYLGLPKKAALKETEQVKAQAGEMFEQVHQGGVSNESSPSRHSLLESEEITFDSSGSSTPEAWSISHASSYWDSEDDGPFKAALERANARPISISKSLEDLASTPSQERWKTDPRNDVRMSMEN----------------VSAVPPNTKTSFSDPEQVKMMSLSVPALMQQEMECRNSDCASVSSFYNDRQR-SCNTPSNFSTCSEVASMSSVTGSVMSIYSSEFGYVEVKGTVQFAIHYVQKLGEFHIFVVQCKDLAVADVKRNRSDPYVKCYLLPDKAKYGKKKTCVRKKTLDPTYNEILRFKIPMEMLKTQKLNISVWHNDTFGRNSFLGEVEVDLAEWDFNNTQMNEYLLKGRVQIPTSPKHSFGGEEMSAEIKVALRFLPQTTLSHKNKGNGEVQIWVKECKNLPISRGVAIDPFVKCAILPENNRKSRQKTRVLKRAPNPVFNHTMVYDGFGHDDLKDICVELTVWDHDRLNNHFIGGIRLGPGTGKSYGSEVNWMDSNVAEAALWERMVQTQNEWVEDTLPLRMMVMARMSR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****.***:**: *::**:*** **:::*:*:::* :. :* :** ::*:****:* :**:*:***:*******::* .: * * * . ::*. :***:: ::*:* .. .. .*. ... . *.. .* : : ::.* :. * : . ::.. : :: . *. * .**:.. . . : :: :. . : . . . ..: :: *.* .... * . . . .. ..* . . :*:*. * : :* . : * .:: . *: :** . * . .: .... : . .. :. . :*. . : ::*: . . *. .*: . : . . * . .:.. * : :: . * : .::: *: .. : :.. : :: . : * . :* **** . : * ..*: .*. :*** ** :. *****:.* .*:: : ::: * *: :*:**. ... **.*:::* ** ****::*:* : *::* ** **: * : * .: :*:*:.* ::*:**.:*****:**.:** :****.:***:.**:.* *:*:**.******.**.*::******* ******.* ***** * ****:*.******:** :.*******:*:**.*** *********:** **::..* :: : .. * .*:*:**:::*:. .:* .***:****** :**: ** ::.****:***:..********.: ::.**:********** :** : ********* :*.*:*:**:*:* *******:**:****. *.****:**:: * *:* *****:::*::*:", "identical_positions": 322, "similar_positions": 311, "identity": "14.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130726-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P78508-1", "uniprot_id": "KCJ10_HUMAN", "id": "P78508-1", "name": "ATP-sensitive inward rectifier potassium channel 10", "aln": "MTSVA----------KVYYSQTTQTESRPLMGPG-------------IRRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVWYLVAVAHGDLLELDPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSPLKDLPLRSG------EGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKYIADFSLFDQVVKVASP-------------SGLRDSTVRYGDPEKLKLEESLREQAEKEG----SALSVRISNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JM63-1", "uniprot_id": "KCJ10_MOUSE", "id": "Q9JM63-1", "name": "ATP-sensitive inward rectifier potassium channel 10", "aln": "MTSVA----------KVYYSQTTQTESRPLVAPG-------------IRRRRVLTKDGRSNVRMEHIADKRFLYLKDLWTTFIDMQWRYKLLLFSATFAGTWFLFGVVWYLVAVAHGDLLELGPPANHTPCVVQVHTLTGAFLFSLESQTTIGYGFRYISEECPLAIVLLIAQLVLTTILEIFITGTFLAKIARPKKRAETIRFSQHAVVASHNGKPCLMIRVANMRKSLLIGCQVTGKLLQTHQTKEGENIRLNQVNVTFQVDTASDSPFLILPLTFYHVVDETSPLKDLPLRSG------EGDFELVLILSGTVESTSATCQVRTSYLPEEILWGYEFTPAISLSASGKYIADFSLFDQVVKVASP-------------SGLRDSTVRYGDPEKLKLEESLREQAEKEG----SALSVRISNV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FD27-1", "uniprot_id": "E7FD27_DANRE", "id": "E7FD27-1", "name": "", "aln": "MTSATPPSSRSSSPQKVCHSQTQTDVLKPLLGGGGGGTSTGNGPAALRRRRRVLSKDGRSNVRIEHVSGRGTLYLRDLWTTFLDMQWRYKLFLFSATFAGTWFVFGVLWYLVALVHGDLLEFDPPSNHTPCVMQVQTLTGAFLFSLESQTTIGYGFRCITEECPLAIILLIVQLVITMVMEIFITGTFLAKVARPKKRGETVKFSQHAVVANHEGRPCLMIRVANMRKSLLLGCQVSGKLLQTSQTKEGETVRLDQRNVAFQVDTSSDSPFLILPLTFYHVIDDNSPLRAWAAKGGGWTDPELADFELLVIMSATVEPTSATCQVRTSYLPDEILWGYEFPPVVSLSPSGKYVADFAFFDKVAKTKTPPLFKQAPPSHTQTPQHQGSGEKGADTEKMRLEESYREERGRDRGRVRDQLSVRISNV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.: ** :*** :**:. * ******:********:**::.: ***:******:********:***********:***:*****:.******:.**:******:**:********************* *:*******:***.***:* ::***********:******.**::********.*:*:***************:****:****** ******.:**:* **:*****:***************:*:.***: . :.* .****::*:*.***.*************:********.*.:***.****:***::**:*.*. :* . :.* : .*.**::**** **: :: . ********", "identical_positions": 269, "similar_positions": 81, "identity": "63.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130729-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GL13-1", "uniprot_id": "A0A8I6GL13_RAT", "id": "A0A8I6GL13-1", "name": "", "aln": "MFSQLLFPGSPCSLLASCLLFTIWLPQAVSSDLCPHLLPALGQLPGRQRSASSPIRDQWHNVPRHNARRSSWTEADLARDSGRPRFAPANSRLQFSSLQRGVGTGARPRSVSRAPCLSLLPSGLSSLRRPAGARSHRLFLPGMRCRMLLLLFSLVLVFWGGSVGRSGAGELECNRTRQVACGEKCIPIAWLCNGEQECPDGSDEQCEQTCLGHAQAWQCDNGKCIPASWLCDGASDCVDGSDELNCESLTVCPDYKIYCPGKALCLDAGEHCDAHQNCEDGSLKAHCPHARCLPGQWQCRN-RACVMDSWRCDGIDHCGDASDEQGCASCPEGTVS-CDG-GKCIPESLMCDGRSDCMDGADEPETCGKNCSLLNGGCEGPCSDTHWGVRCSCTPGWRLQPDGQRCEDVDECSLAYGPCGQLCHNTAGSYSCGCIQGHQLYNGTDCRVTDDDVKILIATDKELGILDRRTGIHEKLTPVKSRPSSVAYDLNRNMYFWVDKVLNVFVFGKPNSVPLYPELPPVSSISLDWVTGQLYWASSSARVICAGLSDGRGYVKILEKDLVPEEIVVFPAKRYLYWVDRGKNGVKTIEAAGMDGSDRKMLAVVTTEEPLGLTLDHVTGRLYWISGYKESIETVNVDGHGRHTFPRVFFQDEDPVGLAVFENAFFWANQTQLIRASPRSPKEREVLLQASISAFLVLHKTQQPKSRHSACVPGSCSHLCLLSPIHPKGYKCVCPEGLFLLPSGTCSELKVVFSSGKRLYLLKVSSMGRAIERTLVEEHAGNLYLLDIDWKRNFIYWSNAQGHLVYSSGYSGEKQEIWTQQTVCSANVDIATGNLFWVPCDRGTIHKTSMPGAESYILYSTRNIILQLLLDWPRRALYWVESGKPLQSMTLDGKNRQEVWRGTWAADTRMALDLGSASILCTTKGLGLHSLSLLKNRTRSLNTSWSDVLLVAHAPYLVTADKATLVLWNRKTLEPFSTMKETHIKKMIILVENQEVSDSPVPDPGHKEPVPTAPSLPPVLCARSSVPCQDGKGCIPRESLCNGEDDCQDGSDEKNCFRVCHQPGVFQCLDGSGCIEERYHCDGAEHCSDGSDELGCWRPADDCSLRCDNKTRCIPKSWRCDGKPDCLDRRDEQGCLHEKCSSTEFQCESGQCVSSSLHCDGNRDCLDHSDEEGCPVSWSLQCPEGEMKCPKSGECVLAEWICDHDVDCEDGADEKDCGLKVISCGPRQWACGSGDQCVPDFWHCDGQSDCRDGSDEAGCAPQRCQDSEFQCATTGACLSFSMVCDGREDCADGSDEGGECSSSMCSPEL-CYHSCYQSPTGSVCACAPGFELESNGQICRDVNECQQPSGQPCSQTCINTEGSYICACHPGYLLGSDGHTCKATGAEPILLVSIEFNLFLYGLRSLKEDILATVDKNRVIYSVDYDLVDQKIFWAGPNAESIRWTSMATKKDGMVVQGIKPDCIGVDWIGRNLYWTDGRAGQILAIQLTAVGKGKPEYTVVLDDDLIQPQSLALDPLNGLMYWSEIGEEPRIEQAGMDGNSRKILVNQGLGRPTSIALDQLSWKIFWSDEKFHCIGSVNLDGSGIRMMQLTQIQSPFSVAVFEDKVFWSDLQTRTIQSVEKMTGKDRAVLIKRSGQPFGLKIMHEVLQPRSSSPCLDIGCSHLCLLSPQAKGSCRCPVGLLLADDGITCVSLQESGFVFLVLPTVLTQIYLRNLKTTPSQTTVPEHRTLPFTSVKQLASVDYLVQEKALYLSELNTSDIRLLRLRERGILSWQRVISVRG-TVIDFALDWMSGNIYWIDTENPYINVAFSNGQYPIVLLSENLYRPSSIVLHPPTAVMCLADLGLQDAGRHGSSIECASMDGSQRKVLWLKSPVPVGLALSDSGTRVYWADTGQGLIQSIQLDGSRYRVDHQGLKGLHLFACGQDMMLWTTVDDAQITRVWYN-KAQVSENQWFQVDQKIVDLKVYSVLSQRGNNSCSKDNGGCSHICLPNPEGRTCRCPRGYCLVEGHTCVEAVQCPPTLQCCKDGQRCISKEQICNGHVDCLDGSDEVDCLNPGELHSTSILKKPEAWKRLIPEAFELSQATESTTDVYLGREEMRHPVKTTLTTQMPASESKVPETKGRAETVQSKDLRTATHRPCSQDFCNGNGICIMEGKLRKCRCLVEYGGEFCQEAARGPATGYIALGGVIAVSATLAVLGLFL--HSRRERKFKRTSSKNLDYDKENNQEEENLMKSETFVNEVYDEQESLTSLQTE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A140LJC7-1", "uniprot_id": "A0A140LJC7_MOUSE", "id": "A0A140LJC7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------MRCRMFLLPFSLMLVSLSGSFGRSGAGELECNRTRQVACGEKCIPVAWLCNGEQECPDGTDELCEQTCLGHLQAWQCDNGRCIPASWLCDGASDCLDGSDEVNCESLTACPDYKIRCPGKAQCLDAGEPCDAQQSCEDGSIKAYCPHIRCLAGQWQCQN-RACIMDSWRCDGIDHCGDASDERDCASCPEGTVS-CDS-GKCIPESLMCNGRADCTDGADEPRTCGKNCSLLNGGCEGPCSDTHWGVRCSCTPGWQLQPDGWSCGDVDECSLPYGPCGQLCHNTPGSYSCGCIQGHQLYNGTDCRVTDDDVKILIATDKELRILDRRTGSHEMLIPVKSRPSSVAYDLDRNMYFWVDKVLNVFVFGKPNSVHLYPELPPVSSISLDWVTGQLYWASSSGRVICAGLSDGRGYVKILEKDLVPEELVVFPAKRYLYWVDRSENGVKTIETAGMDGSDRKMLAVVTAEEPLGLTLDHVTGRLYWISGYKESIETVNVDSSGRYTFPRVFFEDEHPVGLAVFENAFFWANQTQLIRTSPSSPKEREVLLHASISAFSVLHKTQQPKSRHSACVPGSCSHLCLLSPIHPKGYKCVCPEGLFLLPSGTCSELKVVFSSGKRLYLLKVSSMGRAIERTLIEEHAGNLYLLDIDWKRNFIYWANAQGHLVYSAGYSGEKQEIWTQQTVCSANVDIPTGNLFWVPCNRGTIQKTRMPGAESFTLYSTQNIILQLLLDWPRRMLYWVESGTPLQRMTLDGKNRQEVWRGTWAADTRMALDLGSASILWTTKGVGLHSLSILKNRTCSLNTSWSDVVMVAHAPYLVTADKAALVLWNRKTLEPFSTLKEPHIKKMIILAENQEVS-----DPGLKEPVPTTPSLPPVLCARSSVPCQDGKGCIPRESLCNGEADCQDGSDEKNCSQICHQPGVFQCLDGSRCIEERYHCDGAQHCSDGSDELDCWRPADDCSMHCDNKTRCIPKSWRCDGKPDCLDRRDEQGCFHEKCSSPEFQCENGQCISSSLRCDGDRDCLDHSDEEGCPVAWSLQCPEGEMKCPKSGECVLAEWICDHDVDCKDGTDEKDCGLKVISCGPRQWACDSGDQCVPDFWHCDGQSDCRDGSDEAGCAPQKCQDSEFQCAT-GACLSFSMVCDGREDCVDGSDEGGECSSSVCSPGL-CYHSCYQSPTGPVCVCAPGFELESNGQICQDVNECQQPSGQPCSQTCINTEGSYICACHPGYLLGPDGHTCKATGAEPILLVSIEFNLFLSGLRSLKEDILTTADKNLAIYSVDYDLVDQKIFWADPNAESIRWTSMATKKDGIVVQGIKPDCIGVDWIGRNLYWTDGRAGQILAIQLTAMGRGKSEYTVVLDDDLIRPQSLALDPLNGLMYWSETGEEPRIEQAGMDGSSRKILVNQGLGHPTSIALDQLSWKIFWSDEKFHCIGSVNLDGSGISMMQLTQIKSPFSVAVFEDKVFWSDLQTRTIQHAEKMTGKDRAVLIKRSGQPFGLKIMHEVLQPRSSSPCLDIGCSHLCLLSPRAKGSCRCPVGLLLADDGITCVSLQESGFVFLVLPTVLTQIYLKNLKTS-QQTTVPEHRILPFTSVKQLASVDYLVQEKALYLSELNTSDIRLLRMKEPGILSWRRVISVKG-TVIDFALDWMSGNIYWIDTDNPYINVAFSNGQYPIVLLSENLYRPTSIVLHPPTAAMCLADLGSQDDGRHGSSIECASMDGSGRKVLWLQSQVPVGLAFSDSGTRVYWADTGQGLIQSIQLDGSRYRVDHQGLKGLHLFACGQDMMLWTTVDDAQITRVWYN-KAQVSESQWFQVDQKIVDLKVYSVLSQQGNNSCSRDNGGCSHICLPNPEGKTCWCPNGYCLVDGHTCVEAVQCSPMSQCCKDGQRCISKEQICDGHVDCLDGSDEVDCLNPGNVHSTSILKKPEARKRLISEAFKLFQATESTTNVYLGEEEMRHPVRKTLTSQMPASGSKVPETKGRAETRQSKDLQTATHMSCSQDFCNGRGTCIMEGKLRKCRCLVEYGGEFCQEAARGPVSGYVALGGAVALSAALAIWGLFL--HSRRERKFKRTSSRNLDYDKENNQEEENLMKSETFVNEVYDDQESLTSLQTE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32TH74-1", "uniprot_id": "A0AB32TH74_DANRE", "id": "A0AB32TH74-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------MGLFVQLNVVLG-------IFLLLRAERVLAAVVSEDVALPYCRLGFQLCEDRSG--------------------CVLNTHLCDGENDCDDGSDEDNCP------------------------------------------TVCSVGHFQCAHGKMCIWLRQVCDGVPQCQDRSDELNCFKPDDGCAHRCDGNTRCVPESFVCDGDVDCVDGSDE------------ANCE-------------------ENPD-----------------------------------------------DDD-------DDDEDLLD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKEEMTGEHEVSQN-----------VPATKG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLRCSIASKLCRDGTDCVMLNHVCDGELDCKDGSDEEDCPVQCES-GQFQCAHGKKCIDRRQLCDGVPQCQDRSDELNCFKPDDDCAHRCDENTRCVPESFVCDGDPDCVDGSDEANCGEESCSSAEWQCSSGQCVSLSMRCDGHSDCRDHSDEEDCAE--PPPCSTN-RRCPKSHECLLDEWMCDGETDCKDGTDEKNCKESPVQCGEYQFSCSSKTQCIPQSWRCDGSEDCRDGSDESACASVSCPPHLFQCGS-SECVEFSQLCNGVTNCLDGSDEGGSCQTEKCSEQLKCAQDCHSTPAGARCGCRMGYKPVDDGLRCADVDECVERP-NICSHRCNNTLGSFQCSCSHGYVLEPDGHSCKITG-EPYLLASVQSEVFLLGLRSSSLDILLSAEKR-FVLSLDYDWQKQRVYWINLNTDTIKWLSLDQKNKGTFLKGISADSLAVDWVARNLYWTDSENSQINAVRLDSEIGRSTDRVMILGEDLGQLRSIALMPQKGIMFWSETGDEAQIERAGMDGSDRRVLVSKSLRWPVSLTVDSLHQRIYWTDEKLKCIGSANIDGGDVKLLQLMETPSPFSVSVFNDQVYWSDTKRGTIQRAHKTTGKQRQVLLKRPGQPFGLKVIHGLLQEDVSNPCESQGCSHLCVLAPGLKAVCKCSTQFLLDEDGLTCSKPKDSSFLLFLSPAAVTQVYLQNRHSDVTPQKWPEHRRFDLPKMNHPNMLDLVLRDLTLYVSDTDQPLVGLFKMKDAALVPRGKLFQLHKDSVRVFSVDWITLNVYWSSEKLPGIQVTSPDGRFTSVLIREGVGIIESIGLEPPSGRLCFSNR-IQEG--KMSMVECVFMNGLNRTVVWRNSVRPTSLILTDEGNRVYWADTGLAVIASVGTDGSGYKEIKT-EEGLMAFTLVNKVLVWITKKDS--TKCWFSEDEQRSGKLWFEVDTEIVNLKAFTKSRQKGTNLCSNGNGGCNQLCLAFPGGKTCRCAHDHRLLDDGDCRLESHCPENSKPCLSEDMCLPLEQFCNGVADCPDHSDE-NCLDDKQYKTIGINPKSFAPG---------------------------------------LSENIVPAN--------------VESEMCDIKLCKGNGKCVSRNGKTVCDCHPEFSGENCENRS-GLLQGPVLYG-VIGLCAGVVVLAVTVGIIQRKKATNQRRAAHTVDMQETGMKELEKRREASSARSNGKDTEVSEENVVTSVD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : * . * . .* .: :.:.: * * * * :. *: : **** .** ***** ** * *::** : : *: ***: :* * *** .* . :* . **. :*:***::*:* ** **:** ..** :** *** *.: :** **:*: :: *.. **. :* *: *: :* *:**..*: : :*:** **:*****::* *.. * *** .*. **:.* ***. :*.* ****.*::* ***: :**::***:*:*: ***.***:* ** .* .*.***.*:**..***:* *::***. ** ******.*. . *. . :**** **:* **:** :.**:**:***:* . :.** *::*.* **:*: *:***..********:.**. * ***.: . *:.** :*:* :* *******.*.:. ** * * :.*:.:*:*. * * *:: .:* * **:** : . : **: * ** **: *:* **:* .***:** ** ** **.*:: ::** **** . *** :.:*. : *:*** .*:::* . *:::*:* *: *:.* .::**..*.:.***:.*******.. .** *::* : ..: .::*.:** : :*:** * :*:*:*** *:*.:**:*****..*::**.:.* *.*:::*.* :*:*:***::****.*:**..: ::** : *****:**:*:*:*** : *** ..* ***:* **:**.*******::* :** *.** . ******:*:* *. *:*.. :** :**:** . ::*.*:::: *:.:**:**:* :: . **** : :..::: :* :::: :**:*: : . : *::::: .::. :::.:: :* *::**:: *:** . . * *:*: .:*::. **: *.: ** *.**:. :*::: *: : * :**. *:* *.*:* :* *..* ::*.*.******** .:* *: *** *: : :** *: :.:::* * .*: *: *:. . * * . **:** :**:**.:: *:*.* **..****.::**. * *:** *...: *::. * :*. : * . : *:. **:*:* .** * *** :**: : :: .* *. * * . ** . . *. .:*:*.* *: .. * * *:.** *:: : * * : * .:.:.* :.: .: : .*:: . :* :::.:* :: . :* *: ::.: .: * : * .: *. ", "identical_positions": 531, "similar_positions": 460, "identity": "23.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130730-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RXF5-1", "uniprot_id": "ZBT42_HUMAN", "id": "B2RXF5-1", "name": "Zinc finger and BTB domain-containing protein 42", "aln": "--------------------------------------------------------MEFPEHGGRLLGRLRQQRELGFLCDCTVLVGDARFPAHRAVLAACSVYFHLFYRDRPAGSRDTVRLNGDIVTAPAFGRLLDFMYEGRLDLRSLPVEDVLAAASYLHMYDIVKVCKGRLQEKDRSLDPGNPAPGAEPAQPPCPWPVWTADLCPAARKAKLPPFGVKAALPPRASGPPPCQVPEESDQALDLSLKSGPRQERVHPPCVLQTPLCSQRQPGAQPLVKDERDSLSEQEESSSSRSPHSPPKPPPVPAAKGLVVGLQP-------LPLSGEGSR-ELELGAGRLASEDELGP--------------GGPLCICPLCSKLFPSSHVLQLHLSAHFRERDSTRARLSPDGVAPTCPLCGKTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHTVVHTREKPHACRWCERRFTQSGDLYRHVRKFHCGLVKSLLV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q811H0-1", "uniprot_id": "ZBT42_MOUSE", "id": "Q811H0-1", "name": "Zinc finger and BTB domain-containing protein 42", "aln": "--------------------------------------------------------MEFPEHGVRLLGRLRQQRELGFLCDCTVLVGDARFPAHRAVLAACSVYFHLFYRDQPASSRDTVRLNGDIVTVPAFSRLLDFMYEGRLDLHNLPVEDVLAAASYLHMYDIVKVCKGRLRKKDPDLETRTLGT-ELPGQPPHPLPSWSPAFCQAAPKAKHPSLGVKATHPLPTFGPPSWQVAEQSSGALDLSLKPSPRPEQVHPPCRLQTSLCSSVQQVAQPLVKAEQDSFSEQDSSSPQSADRSPP-PVCASAAQGLAVDLEP-------LHIEGTGSQ-QLGLPAEPVLDSEELGP--------------SRHLCICPLCCKLFPSTHALQLHLSAHFRERDSVRARLSPEGSVPTCPLCSKTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHAVVHTREKPHACRWCERRFTQSGDLYRHVRKFHYGLVKPLLV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58HQ89-1", "uniprot_id": "A0AC58HQ89_DANRE", "id": "A0AC58HQ89-1", "name": "Zinc finger and BTB domain-containing protein 18", "aln": "MHLFKAAWLVFEMGLDLLLFVYKCVLKSTCHEWPPSVYLTSSFSCFFFPARFSSIRMEFPDHSRQLLQCLSQQRQQGFLCDCTVLVGETRFRAHRAVLASCSMYFHLYYRDQLD-KRDVVLLNSDIVTVSAFSLLLEFMYEGKLEFSAIPVEDVLAAASYLHMYDIVKVCKSKLKEKELLPEEQQKAN----------------GVNYVAETCVLTAGKTKAHVSSSAS---SQRSRDDTDCALDLSLKPVWIGEFSG-----QLALDSQ-QQDTQTLVKEQHDVLSEQEDADPASPESRRFGNNGRSAAVTGFSELFPRNKHEDLMEEELSGVRSQRQLGDSEGDDEEDLASSDISTSSGVLLSSAGAQVCVCPLCSKVFPNPHVLQLHLSSHFREKDGVRSKLSPDGSVPTCSQCGKTFSCMYTLKRHERTHSGEKPYTCAQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCGLVKTLAIG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****:*. :** * ***: ***********::** *******:**:****:***: .**.* **.****..**. **:*****:*:: :**********************.:*::*: : . . .* .. .. .** . : . : :::. *******. * * .* *. * :*.*** ::* :***:.:.. . .** * * : . * : : * ..::*.. . :*:****.*:**..*.******:****:*..*::***:* .***. *.***** ******************.***************:***********:***************:**** ****.* : ", "identical_positions": 215, "similar_positions": 92, "identity": "42.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130731-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUU2-1", "uniprot_id": "GZF1_RAT", "id": "D3ZUU2-1", "name": "GDNF-inducible zinc finger protein 1", "aln": "---------MESGTVLLESKSSPLNLLHEMHELRLLGHLCDVTVIVDYQGVREDFMAHKAVLAATSKFFKEVFLNEKRADGTRTNVYLSEVQVVDFASFLEFVYTARVRVKEDRVQQMLEVAEKLKCLDLSETCLQLKKQMLESVLLELQNFSESQEVEASSGPQVSVTPSSKASVPAGEDAHSNGLVDSSDYPIERLGNGLSPETPSKKCKEKLDKKKDVAKPPFPKIRRASGRLAGKKVFVEIPKKKYTRR--LREQQKSAEEAAKN--DKCPQDQSPDNERVEAEPASKSEA---CPASVEREES-LQKVEGEKEEEEGKDGEE--KKKSNFQCTVCDKAFLYEKSFLKHIKYHHGVATEVVYRCDTCGQTFANRCNLKSHQRHVHSSERHFPCEMCAKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKTALRLHERTHTGDKPYGCTKCDAKFSQPSALKTHLRVHTGERPFVCDECGARFTQNHMLIYHKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCLRTFAQRNSLYQHIKVHTGERPYCCDQCGKQFTQVNALQRHHRIHTGEKPYMCNACGRTFTDKSTLRRHTSIHDKNTPWKSFLVIVDG-------SPKNDEGQKTEQPDEEYASPKLS-------DRLLSFGENSHFN-------------NLLEVQGNVP--AVQENSSTD--TACKA---VVSQDALLTTSISALGELTPQTVSMPAH-------LPSLTNME----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4VBD9-1", "uniprot_id": "GZF1_MOUSE", "id": "Q4VBD9-1", "name": "GDNF-inducible zinc finger protein 1", "aln": "---------MESGTVLLESKSSPLNLLHEMHELRLLGHLCDVTVSIENQGVHEDFMAHKAVLAATSKFFKEVFLNEKSADGTRTNVYLNEVQAVDFASFLEFVYTAKVRVEEDRVQQMLEVAEKLKCLDLSETCLQLKKQMLESVLLELQNFSESQEVEASSGPQVSVTPSSKASVP-GEDAHSNGLVDSSDYPIERLGNGLSPETPSKKCKEKLDKKKDVAKPPFPKIRRASGRLAGKKVFVEIPKKKYTRR--LREQQKSAEEAAEN--DKCPQDQSPDNERMETEPAAKSEA---CPASVELEES-LQKVEGEKEEEEGKDGEE--KKKSNFQCTVCDKAFLYEKSFLKHIKYHHGVATEVVYRCDTCGQTFANRCNLKSHQRHVHSSERHFPCEMCAKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKTALRLHERTHTGDKPYGCTKCDAKFSQPSALKTHLRVHTGERPFVCDECGARFTQNHMLIYHKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCLRTFAQRNSLYQHIKVHTGERPYCCDQCGKQFTQVNALQRHHRIHTGEKPYMCNACGRTFTDKSTLRRHTSIHDKNTPWKSFLVIVDG-------SPKNDEGHKTEQPDDEYASPKLS-------DRLLSFGENSHFN-------------NLLEVQGNVP--AVQENSSTG--AACKA---VVSQDALLTTSISALGELTPQAVSMPAH-------LPSLTNME----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H116-1", "uniprot_id": "GZF1_HUMAN", "id": "Q9H116-1", "name": "GDNF-inducible zinc finger protein 1", "aln": "---------MESGAVLLESKSSPFNLLHEMHELRLLGHLCDVTVSVEYQGVRKDFMAHKAVLAATSKFFKEVFLNEKSVDGTRTNVYLNEVQVADFASFLEFVYTAKVQVEEDRVQRMLEVAEKLKCLDLSETCFQLKKQMLESVLLELQNFSESQEVEVSSGSQVSAAPAPRASVA-TDGPHPSGLTDSLDYPGERASNGMSSDLPPKKSKDKLDKKKEVVKPPYPKIRRASGRLAGRKVFVEIPKKKYTRR--LREQQKTAEGDVGD--YRCPQDQSPDRVGTEMEQVSKNEG---CQAGAELEEL-SKKAGPEEEEEEEEEDEEGEKKKSNFKCSICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQTFANRCNLKSHQRHVHSSERHFPCELCGKKFKRKKDVKRHVLQVHEGGGERHRCGQCGKGLSSKTALRLHERTHTGDRPYGCTECGARFSQPSALKTHMRIHTGEKPFVCDECGARFTQNHMLIYHKRCHTGERPFMCETCGKSFASKEYLKHHNRIHTGSKPFKCEVCFRTFAQRNSLYQHIKVHTGERPYCCDQCGKQFTQLNALQRHRRIHTGERPFMCNACGRTFTDKSTLRRHTSIHDKNTPWKSFLVIVDG-------SPKNDDGHKTEQPDEEYVSSKLS-------DKLLSFAENGHFH-------------NLAAVQDTVP--TMQENSSAD--TACKADDSVVSQDTLLATTISELSELTPQTDSMPTQ-------LHSLSNME----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58I6D5-1", "uniprot_id": "A0AC58I6D5_DANRE", "id": "A0AC58I6D5-1", "name": "", "aln": "MRDVHKPEKMGDRFIQLHSNSHHKNLLGAMWKLRTRGNLCDITIQVDFQGELEEFEAHQVVLAASSAYFKTHLLTEDPVN----KMFLCDFSPHSFSKFLEYAYSGKMEVEKSGIANILQMAKLLKCQDLVDVC-----------EVEIPNVASEECVEKDAEIKTKHVKK------------------------------------AIKRKKRVKSAKYVSES--DVLGRRSGRLAGRRVNVEFPQKKLKRQTEILDEPDNAEGEEEQRIAEHPEAESSKNALDDTSKDTIDDSGSESPAYVPQDDPDESDFLPDEEMEADEAEKKVKKEIAKYTCEVCSRYFYYEKSYLKHLKVSHGVQTDTTLRCDICQQTFANRCNLKIHQRHVHSDERLFPCDVCNKTFKRKKDVTRHRRHVHEGGTDRHYCQECGKSLSSKTALTLHERTHTGLKPFKCDECDSRFSQSSALKTHKRIHTGEKPFACDLCDARFTQNHMLAYHRRCHTGEKPFMCENCGKSFASKEYLKHHNRIHSGSRPYKCETCGRAFAQRNSLHQHVKIHTGERPYHCKDCDKQFTQLNALQRHQRIHTGEKPYMCSMCGRTFTDKSTVRRHTLTHDKQTPWKNYLVVLEGNVEDRAKKPKGSSQKKEKAAAAVSKAQALQSDVGKTQEVMATIGEPVTISGDWTGSGTIALVSGLTVIQTEVPSGTLQPLVTSDGTSVISLDASAIGMPVPFSIPISVAHSLASGSVPISVAGHVSEAILESSTNAETSEAENVLASTAIEECVTVQAVTVEETDCAETQQENDQNTHTADDSNNMEISVGDTAE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : *.*:* *** * :** *:***:*: :: ** ::* **:.****:* :** :*.*. .: :::* :.. .*:.***:.*:.::.*::. : .:*::*: *** ** :.* :*: *.:..: ** .: :.. . . * *.::.. * * :. : * ******::* **:*:** .*: : :: ..** : . *: :*... : . : .:. . * . :: .. ::* * : :: *: ::: * :*.: * ****:*** * *** *:.. *** * ********** *******.** ***::* *.*******.** :***** :** * :***.******* ******** :*: * :*.::***.****** *:****:**.** *.********* **:******:*****.******************:**:*:***.* *:*******:**:*:******* *.:*.*****:******:******:*:**. **********:**** ***:****.:**:::* .**... :* : . : *. : : ::.* : .* :* ** ::* ::. :. . .:. . :: .** .*:. : .:.. * * :* * ", "identical_positions": 302, "similar_positions": 203, "identity": "36.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130805-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZNY2-1", "uniprot_id": "A0A8I5ZNY2_RAT", "id": "A0A8I5ZNY2-1", "name": "One cut domain family member", "aln": "-----------------------------------------------------------------------------MELSLESLGG-------------------------LHGVT-HAQAGELLSPG----------------------------------------HARSAAAQHR--------SLVASGRPGLVAGMASLLD--------GGGAGGGG-AGGAGAAGAAGGGPDFRG--ELAGPLHPAMGMACEAPGLGG----------------------------------------------------------------------TYTTLTPLQHLPPLAAVADKFHQH----AVAGAHGGHPHAHPHPATAPPPPPP-QRLAAS-VSGSFTLMRD---------------------------ERAALASVGHLYGPYGKELPTMGSPLS------------------------------------------------------------------------------------------------------------------------------PLPSALPPALHSAPQPPPPPPP--LAAYGAPGHLAGDKLLPPAAFEPHAALLGRA-----------------------------EDALARGLPGG-------GGGAGGGGAAGGAAAGLLAPLGGLATAGAHGPHSGGGGP----------------GGGGGAGGGSGGPGAGAAAEEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKE-----------------------------------------------------------------QDQQKERALQPKK--QRLVFTDLQRRTLIAIFKENKRPSKEMQAT-----ISQQLGLELNTVSNFFMNARRRCMNRWAEEPGATPG-TATATATFSKA---------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K557-1", "uniprot_id": "ONEC3_MOUSE", "id": "Q8K557-1", "name": "One cut domain family member 3", "aln": "-----------------------------------------------------------------------------MELSLESLGG-------------------------LHGVT-HAQAGELLSPG----------------------------------------HARSAAAQHR--------SLVASGRPGLVAGMASLLD--------GGGAGGGG-AGGAGAAGAAGGGPDFRG--ELAGPLHPAMGMACEAPGLGG----------------------------------------------------------------------TYTTLTPLQHLPPLAAVADKFHQH----AVAGAHGGHPHAHPHPATAPPPPPP-QRLAAS-VSGSFTLMRD---------------------------ERAALASVGHLYGPYGKELPTMGSPLS------------------------------------------------------------------------------------------------------------------------------PLPSALPPALHSAPQPPPPPP---LAAYGAPGHLAGDKLLPPAAFEPHAALLGRA-----------------------------EDALARGLPGG-------GGGAGGGGAAGGAAAGLLAPLGGLAAAGAHGPHSGGGGP----------------GGGGGAGGGSGGPGAGAAAEEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKE-----------------------------------------------------------------QDQQKERALQPKK--QRLVFTDLQRRTLIAIFKENKRPSKEMQAT-----ISQQLGLELNTVSNFFMNARRRCMNRWAEEPGATPG-TGTATATFSKA---------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60422-1", "uniprot_id": "ONEC3_HUMAN", "id": "O60422-1", "name": "One cut domain family member 3", "aln": "-----------------------------------------------------------------------------MELSLESLGG-------------------------LHSVA-HAQAGELLSPG----------------------------------------HARSAAAQHR--------GLVAPGRPGLVAGMASLLD--------GGGGGGGGGAGGAGGAGSAGGGADFRG--ELAGPLHPAMGMACEAPGLGG----------------------------------------------------------------------TYTTLTPLQHLPPLAAVADKFHQHAAAAAVAGAHGGHPHAHPHPAAAPPPPPPPQRLAAS-VSGSFTLMRD---------------------------ERAALASVGHLYGPYGKELPAMGSPLS------------------------------------------------------------------------------------------------------------------------------PLPNALPPALHGAPQPPPPPPPPPLAAYGPPGHLAGDKLLPPAAFEPHAALLGRA-----------------------------EDALARGLPGG-------GGGTGSGGAGSGSAAGLLAPLGGLAAAGAHGPHGGGGGP----------------GGSG------GGPSAGAAAEEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAACKRKE-----------------------------------------------------------------QEQQKERALQPKK--QRLVFTDLQRRTLIAIFKENKRPSKEMQVT-----ISQQLGLELNTVSNFFMNARRRCMNRWAEEPSTAPGGPAGATATFSKA---------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58I1Y3-1", "uniprot_id": "A0AC58I1Y3_DANRE", "id": "A0AC58I1Y3-1", "name": "", "aln": "-----------------------------------------------------------------------------MELTMENIGN-------------------------MHGVASHGQPGDLMNSS----------------------------------------HGRPPSASHR--------NLVSHGRSAMVSSMASILE--------GAG--------------------DYRSDPALSGHLHPAMTMCESGMSLSN----------------------------------------------------------------------TYTTLTPLQHLPPISTVSDKFHHA------------HPHPHHHAAH--------QRLATGNVSGSFTLMRD---------------------------DRG-LASMGNLYGHYPKEMSGMGQPLS------------------------------------------------------------------------------------------------------------------------------PLSNGLG-SLHNSQQA--------LSAYGPGAHIPNDKMLSPGGFESHAAMLSRS-----------------------------EEHLARSLGGH-------GHGMISNLNGMHAHGHLHTPANGSMLADRE---RHGGGP----------------GQSG-------GSGQ---VEEINTKEVAQRITAELKRYSIPQAIFAQRILCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAGNVQEKGA-------------------------------------------------------------GAAQRQKHGAQEAAAGVHRPTAPNTHRHLQGEQTTQQGDADHHLAAAGPGALHRQQLLHERPAPLRGPLAGRARQQPRTARDFSQHLFQGVNAEEDASTHVQHMMIYGAHQNSSD------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NJB5-1", "uniprot_id": "ONEC_DROME", "id": "Q9NJB5-1", "name": "Homeobox protein onecut", "aln": "MDSLNDIIDHQTFSQELVEDASEFITVGHHSERPSQSSQQPNSGQDLTMSMQDIISCPVKHRTCSASGSGSASGSDSVVMVIDALGQGNRQSAYQIVPQQLQQRNMPLPFGLLERDRQHMQHGREVNTSPVDFVSSDINLDGLTVDADVSQTDHSQETAVKQEQKLLIVQSKSQDQSHRRIRMLVDVSSVNSGLGVHVDDMDEISSDGVGCDDEGVTLSHQHLLEQEEQFGLTSHHPHLQPHTQIIHGLHQRSTHSEMGLDNGHGEVLSVIVHSQDSDKEDCEENDDGDAEGDLENEDDDERDSRSREQLLSHSSYQTLTSVNDRLSSPGFSQTSYATLTPIQPLPPISTMSEKFAYSG---HISGGDSGDTDVNGDGAGGGVVEVGEVTNQSSEATGTVSISSGNATSSVCSNNDCSSFSALSMPIGSGHLGLGVLSGVQSPFSSYEKLSSMISPPPNNYLVSCDLHSSVSGRVINSSHLQLSHNGNKKESGTHEHTHRPADVNGGKFSYTGHISRGDSVDNDVNGEKFSFSDHISGGDSGDEDANREKFIYSDHISEGENGPDVNSGTNWLQMHSEREVRLHMPVPAELEARFHISSERRTRLNVP-PARGSLSRHLAPNAPICPADWKADDWKHSNAGVVSLTADMPVVVSLTPTPPPLRDDSVSGIKQNERSSPGHREQYFLDKSQEPSSVVADQCSPGINGTPQSVCVIHQQSPSALGNGFQSSSQQAKVSSCASPKGTVSSGGAVSNRIANSSDMEEINTKDLAQRISAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMYKWLQEPEFQRMSALRMAAAQIPQRAPLSSGMSLGSATGPSGSTGTIPTDLDPHGGPTMIQNPLTNESDSSPASTPVTSVLVGSVVSCRRKEEPQIEQMPQPKKPRLVFTDLQRRTLQAIFKETKRPSKEMQVT-----IARQLGLEPTTVGNFFMNARRRSMDKWRDDDSKSTMHVAHSRQQQDEQQKDNAHTHSQSQIQDQNHSQNQAIHNSMSQDPYSNLHTTAMSPLGAFDEDADMDLELESHDFDLVDPDEHGDTNDPNGDML", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: :* :. * * * :... :.:. .** . * * * .* .: . * . : : ** . . . . :*:****:* ***::::::** ... : . * :. .:*:.:: . . *:.: :. * * . :. * . *:. * :* : : : . *:. : : *. ::.. ..: . *. * .. . . : . . . *.* * . . ******::****:****************:*******************************:***************:*. : ..: . . * . .: :*: .: ..:.: .: :** * : . : .* * : : . : . ", "identical_positions": 120, "similar_positions": 130, "identity": "11.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130814-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91W29-1", "uniprot_id": "COX42_MOUSE", "id": "Q91W29-1", "name": "Cytochrome c oxidase subunit 4 isoform 2, mitochondrial", "aln": "---MFSRAARSLVMRTG-LRTRGT----GTHSPGDAAGS-QRRMTPY-VDCYAQR-SYPMPDEPFCTELSEEQRALKEKEKGSWTQLSQAEKVALYRLQFHETFAEMNHRSN-EWKTVMGCVFFFIGFTALVIWWQRVYVFPKKVVTLTEERKAQQLQRLLDMKSNPIQGLAAHWDYEKKEWKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q91Y94-1", "uniprot_id": "COX42_RAT", "id": "Q91Y94-1", "name": "Cytochrome c oxidase subunit 4 isoform 2, mitochondrial", "aln": "---MFSRATRSLVMKTGGLRTQG------THSPGSAASSSQRRMTPY-VDCYAQR-SYPMPDEPYCTELSEEQRALKEKEKGSWAQLSQAEKVALYRLQFHETFAEMNHRSN-EWKTVMGCVFFFIGFTALVIWWQRVYVFPKKVVTLTEERKAQQLQRLLDMKSNPIQGLSAHWDYEKKEWKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96KJ9-1", "uniprot_id": "COX42_HUMAN", "id": "Q96KJ9-1", "name": "Cytochrome c oxidase subunit 4 isoform 2, mitochondrial", "aln": "---MLPRAAWSLVLRKGGGGRRG------MHSSEGTTRG-GGKMSPY-TNCYAQR-YYPMPEEPFCTELNAEEQALKEKEKGSWTQLTHAEKVALYRLQFNETFAEMNRRSN-EWKTVMGCVFFFIGFAALVIWWQRVYVFPPKPITLTDERKAQQLQRMLDMKVNPVQGLASRWDYEKKQWKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R6I1-1", "uniprot_id": "F1R6I1_DANRE", "id": "F1R6I1-1", "name": "Cytochrome c oxidase subunit 4", "aln": "---MLSSRALVRGLQSGFWRRLS------TSSGIWAAHTHDVDVTDCSVPQYNNRLDTPLPDVPFVRNLSAEQKKLKEKEKGPWTQLSKEEKLAIYRLTHELSFPEMRKGSK-EWMTVLAGVFFFLGFTGLLVWWQRVFVYGDVPHTLSQEWIEKQTQRMLDMKVNPITGFAHKWDYEKKQWK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P00425-1", "uniprot_id": "COX5B_YEAST", "id": "P00425-1", "name": "Cytochrome c oxidase subunit 5B, mitochondrial", "aln": "------------MLRTSLTKG---------ARLTGTRFVQTKALSKATLTDLPER-WENMPN----LEQKEIADNLTERQKLPWKTLNNEEIKAAWYISYGEWGPRRPVHGKGDVAFITKGVFLGLGISFGLFGLVRLLANPETPKTMNREWQLKSDEYLKSKNANPWGG------YSQVQSK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P00424-1", "uniprot_id": "COX5A_YEAST", "id": "P00424-1", "name": "Cytochrome c oxidase subunit 5A, mitochondrial", "aln": "------------MLRNTFTRAGG------LSRITSVRFAQTHALSNAAVMDLQSR-WENMPS----TEQQDIVSKLSERQKLPWAQLTEPEKQAVWYISYGEWGPRRPVLNKGDSSFIAKGVAAGLLFSVGLFAVVR-MAGGQDAKTMNKEWQLKSDEYLKSKNANPWGG------YSQVQSK-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VIQ8-1", "uniprot_id": "Q9VIQ8_DROME", "id": "Q9VIQ8-1", "name": "Cytochrome c oxidase subunit 4", "aln": "MALRLLNSAVLRQLASQLPKSAQVGSVAAVHTLDKIGKREIVGYGWNGTACYADRVDYPLPAVR-FREPTNEINALRAKEQGDWKKLSTQEIKALYRASFCQTIAEVQAGSG-EWKLHLGVSLLFCAAAIWVAVLMNIFVYDELPVTFDEEHQKAQLQRIIDLEINPVTGLTSKWDYENKKWKN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .* :* : * ::: * *. * * : . .. . : : : . . *: * . : : . : ** * *.: : * ", "identical_positions": 14, "similar_positions": 28, "identity": "7.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130819-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IAA8-1", "uniprot_id": "LTOR1_HUMAN", "id": "Q6IAA8-1", "name": "Ragulator complex protein LAMTOR1", "aln": "MGCCYSSENEDSDQDREERKLLLDPSSPPTKALNGAEPNYHSLPSARTDEQALLSSILAKTASNIIDVSAADSQGMEQHEYMDRARQYSTRLAVLSSSLTHWKKLPPLPSLTSQPHQVLASEPIPFSDLQQVSRIAAYAYSALSQIRVDAKEELVVQFGIP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CQ22-1", "uniprot_id": "LTOR1_MOUSE", "id": "Q9CQ22-1", "name": "Ragulator complex protein LAMTOR1", "aln": "MGCCYSSENEDSDQDREERKLLLDPSSTPTKALNGAEPNYHSLPSARTDEQALLSSILAKTASNIIDVSAADSQGMEQHEYMDRARQYSTRLAVLSSSLTHWKKLPPLPSLTSQPHQVLASEPIPFSDLQQVSRIAAYAYSALSQIRVDAKEELVVQFGIP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FBZ6-1", "uniprot_id": "E7FBZ6_DANRE", "id": "E7FBZ6-1", "name": "Ragulator complex protein LAMTOR1", "aln": "MGCCFSSDSETTDPDGDEVKPLIPDPNQERKPTNGSERNADNLPSNRTDEQALLTVILQRTALNIIDVSAVDSQGMEQHEYMDRARQYSTKLEVLSRTLSQ-KKPVPLPSLTSQPHQVLAADLVPHADVQQVSKIAAYAYSAISQIKVDAKEELVVQFAIP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:**:.* :* * :* * *: .. *. **:* * ..*** ********: ** :** *******.*******************:* *** :*:: ** **************:: :*.:*:****:********:***:***********.**", "identical_positions": 109, "similar_positions": 29, "identity": "67.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130819-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q13796-1", "uniprot_id": "SHRM2_HUMAN", "id": "Q13796-1", "name": "Protein Shroom2", "aln": "MEG--AEPRARPERLAEAETRAADGGRLVEVQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQEAICLVKGSHKTLKLVVKRRSELGWRPHSWHATKFSDSHPELAASPFTSTSGCPSWSGRHHASSSSHDLSSSWEQTNLQRTLDHFSSLGSVDSLDHPSSRLSVAKSNSSIDHLGSHSKRDSAYGSFSTSSSTPDHTLSKADTSSAENILYTVGLWEAPRQGGRQAQAAGDPQGSEEKLSCFPPRVPGDSGKGPRPEYNAEPKLAAPGRSNFGPVWYVPDKKKAPSSPPPPPPPLRSDSFAATKSHEKAQGPVFSEAAAAQHFT---ALAQAQPRGDRRPELTDRPWRSAHPGSLGKGSGGPGCPQEAHADGSWPPSKDGAS---SRLQASLSSSD----VRFPQSPHSGRHPPLYSDHS-----PLCADSLGQEPGAASFQNDSPPQVRGLSSCDQKLGSGWQGPRPCVQGDLQAAQLWAGCWPSDTALG----ALESLPPPTVGQSPRHHLP-----QPEGPPDARETG----RCYPLDKGAEGCSAGAQEPPRASRAEKASQRLAASIT-------WADGESSRICPQETPLLHSLTQEGKRRPESSPEDSATR--PPPFDAHVGKPTRRSDRFATTLRNEIQMHRAKLQKSRSTVALTAAGEAEDGTGRWRAG-LGGGTQEGPLAGTYKDHLKEAQARVLRATSFKRRDLDPNPGDLYPESLEHRMGDPDTVPHFWEAGLAQPPSSTSGGPHPPRIGGRRRFTAEQKLKSYSEPEKMNEVGLTRGYSPHQHPRTSEDTVGTFADRWKFFEETSKPVPQRPAQKQALHGIPRDKPERPRTAGRTCEGTEPWSRTTSLGDSLNAHSAAEKAGTSDLPRRLGTFAEYQASWKEQRKPLEARSSGRCHSADDILDVSLDPQERPQHVHGRSRSSPSTDHYKQEASVELRRQAGDPGEPREELPSAVRAEEGQSTPRQADAQCREGSPGSQQHPPSQKAPNPPTFSELSHCRGAPELPREGRGRAGTLPRDYRYSEESTPADLGPRAQSPGSPLHARGQDSWPVSSALLSKRPAPQRPPPPKREPRRYRATDGAPADAPVGVLGRPFPTPSPASLDVYVARLSLSHSPSVFSSAQPQDTPKATVCERGSQHVSGDASRPLPEALLPPKQQHLRLQTATMETSRSPSPQFAPQKLTDKPPLLIQDEDSTRIERVMDNNTTVKMVPIKIVHSESQPEKESRQSLACPAEPPALPHGLEKDQIKTLSTSEQFYSRFCLYTRQGAEPEAPHRAQPAEPQPLGTQVPPEKDRCTSPPGLSYMKAKEKTVEDLKSEELAREIVGKDKSLADILDPSVKIKTTMDLMEGIFPKDEHLLEEAQQRRKLLPKIPSPRSTEERKEEPSVPAAVSLATNSTYYSTSAPKAELLIKMKDLQEQQEHEEDSGSDLDHDLSVKKQELIESISRKLQVLREARESLLEDVQANTVLGAEVEAIVKGVCKPSEFDKFRMFIGDLDKVVNLLLSLSGRLARVENALNNLDDGASPGDRQSLLEKQRVLIQQHEDAKELKENLDRRERIVFDILANYLSEESLADYEHFVKMKSALIIEQRELEDKIHLGEEQLKCLLDSLQPERGK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U0T1-1", "uniprot_id": "A0AB32U0T1_DANRE", "id": "A0AB32U0T1-1", "name": "", "aln": "MSDRRMEILQAGNGALSPGDAGEDGPLFVELQRRGGSPWGFTVRGGLEYREPLIITRVEDGS-GAARGRLQIGDQIVSVNSVLLSGYRLEAICLIKSSHNTLSLGVIRRNESSCRPHSWHSAKSSESSNPNDSKSEPNPAPDPTWQTKCDPGSPTKEFTSCWGQTNLRQASCQFSSVRNMESVEPSSHAFSKEQPLTSKPNGG--ADHEVLESAISKPALPGNAFSGTADHGAPRGANPTEGVFYR-----------GDLTVPSDCHRYLQIPIGNGGRVSPSVEEQSSSRLSSTARSNHRPVWHIPENKMS-SSEAPPAPPLRSDSFTATRVHEKSLVGLFPEGHTVYPLQRPPCRAVDRQLEDVRHSYNSPPKKDYLEPYLPVEDYPNQLNPTKLFSLSSTDVRQGQNPFASEFQHQRQHSDDSPFSVYNNSTCSSKSQSVGSYYRSLQDLPNNVSNQNKTRTSTVFDPNHDGQAHFRYYCITAQQPYLESSSHCRMVDEQSSEMGKAQGATDRSFVGSQKVIKAKHPQLYLSLPENKRSNGYNKQSISPASAQAVSPISNNLISKHSSVERETQKKKDKPQPSRHIPNHQTEQNSMYTYQHDNPWISKQDLKICPHKTPLLHSLAQESKKMAENSITTASKGGSHESSDASSGKLGRRSDRYATTLRKEIQKKRAQLQKSRSAATLTCSTEVEEDSDIWKSNETSTSSSDGSFTNTYKDHLKEAQAKVLQATSFMRKDLELPGNEVVSAQLPKRPG------------------------QVTRIGGRKRFPMDKKIHSFSEPDKINEVGVEDKAG------------GSFADRYKFFEGSGKAVVQKPIPKQSLLGPTVDHSERKTGEAESIP-------RVLLKQSKSSHSDLN----ADEQQRLGTFAEYEATWNLQKKQVERRNTGRYHSAENILDSGLEESNSALCVHERSRSSPSADFYGQKLPLPPRKLP---------LDSPPEAKD------QQEAHISSASEKEHNALNISKSQESITMSILDNSVEPLGYNQKSR------------SDTKQPAPITSQHLQ------------VPMSEQLLPKNNG--------LIPQHKELETTCPIMASLEVRIQTFS-PEPT-----QERLRLN------TSEPLDGDMHAQVDEHKSERMLSPIPHNSAGSPIPPKQ-KADLTVTSASRTRSPSPQFFPQRLTDEPPANVYKKD-PCSSKVEEPNTPGRKVPIQIVCTENGSERDIRNYLLH-SESSEEPQ---TGQLKTLESSEQCHAPFIAYSNQIEEPILDP-------------FKPMRSNGVS----------EHSEDDLKREELARDIMGKDRSLVDILD-QRKMKTTMDLMEGIFPQGEQILEGAQQRRKAASKQTSPKNAQQRMEES-LSSSVSLVSSSSYYSTSAPKAELLIKMKDMQEQ-----DSEDELTTDLSSKKQELMDSLSKKLQVLREARESLQEDVQDNNALGEEVEATVQSVCRANELEKFRMFVGDLDKVVSLLLSLSGRLARVENALDNLEEGTSADEKQTLTEKRRLLIGQHEDAKELKENLDRRERVVYEILTGYFREEQLADYRHFVKMKSALIIEQRKLEDKIKLGEEQLKCLKESLPLEQRLLY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. * : .. . ** :**:* **:*****::** *: ***:**::*:** .** .:* **:**.:*.: ***:* *****:*.**:**.* * **.* . ******::* *:* :.. ...: *:*. : ...*.:::::*.* ****::: :***: .::*:: .* :* :. :* : * :.:: .::*..: . : ..** .:... * *:: ** ..: : : ... .* * ::..:*::..***. ***::*::* : ** .**.********:**: ***: :*.*. :. : . * : * * . .. * :. * . . * . ::* . *.:* . . ** : :*. *.: .: * : * ... .: :: *: : *.: * . :.. * * *:::: . .:* :: .::: * . *.:: . *. .*..*: .. . . ....* : :: *:.** * *: * . :. :***::*******:**.*: .*.* ::. . ** ** *****:*****:*** :**:******:.:**.: *.*:.:. *::. . .:.:*.::.***********:**:**** *:**: .:: . .* :* * : .*****:**. ::*::*:***:*:****: . *:****:**** :.*.* *:* **:* * . *:.** ..: . * :* .:** : :* :********:*:*: *:* :* *.:** ***::*** .*: .: . ** *******:*.* *: .: *: . * *. .*:: * :*: ..* .:: .*: :. *:* *.:. . ::.* *: . ** : .: . *:*. **.*. . *:: . .* *.: * :.*. *.*: ** *. :* :. :* * *: *::: . .: . : :**** : * .:: . :******* **:***:** : .:* . .:* : **. : ***:** :*. .*:: *: * :*.. *: ..*:***.:*** :: * *:.* ** . * :.. .* *:: :*** *****:*:***:**.**** . *:************:.*::** ****** .* .**:.:::* **. :.::***.:.*:*****************:*** ** .:* *** *****::*:*:************ **** *..** **** *:.**:..*::*****:*******.****************:**::*:*..::*:* **:*:** *****************:*::**:.*: **.****.**************:*****:********* :** *: ", "identical_positions": 586, "similar_positions": 480, "identity": "35.34%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130819-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "H7C241-1", "uniprot_id": "CLD34_HUMAN", "id": "H7C241-1", "name": "Claudin-34", "aln": "MVWFCNSADCQFSVFALTTIGWILSSTSTGLVEWRIWYMKDTSLYPPGIACVGIFRVCIYRRRTNSTTTKFCYRYSYQDTFLPFEISMAQRFLLTASIFGFFGRAFNMFALRNMSMRMFEEDTYNSFVVSGILNIAAGVFNLIAVLQNYDAVINSQGITFLPSLQMPFKPDVQEVGTAIQVAGIGVLPMLLTGMFSLFYKCPP---------------------YGQVHPGISEM--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FDA9-1", "uniprot_id": "E7FDA9_DANRE", "id": "E7FDA9-1", "name": "", "aln": "MAYLAQSVHRQFAGLVLGFVAWIMTASVSGVNDWRIWYVDNTTVITGGVAWVGVWRACFNSHVLDS--AEICKSIGLTDSFTPPEIAAAQVLCMIAIGVGVVANLLAGYAVRNAIFGVDGGHVRLAFVMAGSLYWLTATCSLVPVFWNMSSVLANLTIDFPPEFYLPSTPVKQEVGPGIGIGIGAGCLLIVSGLLLMCYRYPKTKMPLSEENGHFDKSQRNEGCFGVIKESVDEGIINTAFEA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.::.:*.. **: :.* :.**:::: :*: :*****:.:*:: . *:* **::*.*: : :* :::* . *:* * **: ** : : * .*.... : :*:** : : .. :**::* * :.. .*:.*: * .:*: . * * *.: :* .* ****..* :. . ::::*:: : *: * :* :: .:.* ", "identical_positions": 57, "similar_positions": 89, "identity": "23.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130821-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35679-1", "uniprot_id": "ISK4_MOUSE", "id": "O35679-1", "name": "Serine protease inhibitor Kazal-type 4", "aln": "MAMHLWLVTLTLVPLLGMDRELMVSAGSLVFPRMPFCEHMAELPNCPQTPNLICGTDGLTYENECHLCLTRMKTMKDIQIMKDGQC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60575-1", "uniprot_id": "ISK4_HUMAN", "id": "O60575-1", "name": "Serine protease inhibitor Kazal-type 4", "aln": "MAVRQWVIALALAALLVVDREVPVAAGKLPFSRMPICEHMVESPTCSQMSNLVCGTDGLTYTNECQLCLARIKTKQDIQIMKDGKC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FCI0-1", "uniprot_id": "E7FCI0_DANRE", "id": "E7FCI0-1", "name": "", "aln": "MSMG--LLVFGLFLLLSSG-----ASGS---SRKPTCAGMPEILACPMNLAPVCGSDGNTYSNECLLCVERLKTKSDILIAKDGDC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: ::.: * ** . ::*. .* * * * * *. :**:** ** *** **: *:** .** * ***.*", "identical_positions": 32, "similar_positions": 18, "identity": "37.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130827-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86PD7-1", "uniprot_id": "QPCT2_DROME", "id": "Q86PD7-1", "name": "Glutaminyl-peptide cyclotransferase", "aln": "MR---LLLRNYSLMEAVKRLLPRPRKKIYNLGACFELVDIPKISYNPSELSEPRFLEYSNLSDK-LHLREAIDKILIPRVVGTTNHSIVREYIVQSLR-DLD--WDVEVNSFHDHAPIKGKLHFHNIIATLNPNAERYLVLSCHYDSKYMP----GVEFLGATDSAVPCAMLLNLAQVLQEQLKPLK--------------KSKLSLMLLFFDGEEAFEEWGPKDS-IYGARHLAKKWHHEG----------KLDRIDMLVLLDLLGA--PDPAFYSFFENTESWYMRIQSVETRLAKLQ--LLERYASSGVAQRDPTRYFQSQAMRSS-----FIEDDHIPFLRRNVPILHLIPVPFPSVWHTPDDNASVIDYATTDNLALIIRLFALEYLLAGTEAK---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VTH7-1", "uniprot_id": "Q9VTH7_DROME", "id": "Q9VTH7-1", "name": "glutaminyl-peptide cyclotransferase", "aln": "MP---CWRSFIALICLAIIVVVITICQSFHT-NFLTVGRNGTLRYEPTELNLGQMRMIAGLSDP-ENLRKNVQRIAIKRAVSTPGHSEVRNYIVDYLK-KLN--WNVELDIFTQKVPIMSNVTFHNIVARQNPQTQRYLMFGCHYDSKYFK----DFDFMAATDSAVPCALMLNMATILKHQFH-----------------RSQVSLMLVFFDGEEAFGEWSQEDS-PYGSRHLAELWEKHG----------FLDKIDLFVLPDLIGA--KDVVFKKNILDTSGWFHRLVQLELKLFQAG--IVR-------SER-PLFKFEPGID---------VDDDHLPFTRRNVPVIHLISNKYPAVWHQAEDVEMNVDYNTTEQVGLVLRMFVMEYLNSAPSISNTLK-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D4AC85-1", "uniprot_id": "D4AC85_RAT", "id": "D4AC85-1", "name": "Glutaminyl-peptide cyclotransferase", "aln": "MAGGEDRRVVGTRHLLLL-ATILSLTAGILSPVSAVAWTQEKNYHQPAHLNSSSLRQVAEATSISEMWQNDLRPLLIERYPGSPGSYSARQHIMQRIQ-RLQAEWVVEVDTFLSRTPYG-YRSFSNIISTLNPEAKRHLVLACHYDSKYFP-QWDSRVFVGATDSAVPCAMMLELARALDKKLHSLKDVSG---------SRPDLSLRLIFFDGEEAFLHWSPQDS-LYGSRHLAQKMASSPHPPGSRGTN-QLDGMDLLVLLDLIGA--ANPTFPNFFPKTTRWFTRLQAIEQQLSELG--LLK-------DHSLERKYFQNFGYGN------IIQDDHIPFLRKGVPVLHLIASPFPEVWHTMDDNEENLHSSTIDNLNKIIQVFVLEYLHL--------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CYK2-1", "uniprot_id": "QPCT_MOUSE", "id": "Q9CYK2-1", "name": "Glutaminyl-peptide cyclotransferase", "aln": "MAGSEDKRVVGTLHLLLLQATVLSLTAGNLSLVSA-AWTQEKNHHQPAHLNSSSLQQVAEGTSISEMWQNDLRPLLIERYPGSPGSYSARQHIMQRIQ-RLQAEWVVEVDTFLSRTPYG-YRSFSNIISTLNPEAKRHLVLACHYDSKYFP-RWDSRVFVGATDSAVPCAMMLELARALDKKLHSLKDVSG---------SKPDLSLRLIFFDGEEAFHHWSPQDS-LYGSRHLAQKMASSPHPPGSRGTN-QLDGMDLLVLLDLIGA--ANPTFPNFFPKTTRWFNRLQAIEKELYELG--LLK-------DHSLERKYFQNFGYGN------IIQDDHIPFLRKGVPVLHLIASPFPEVWHTMDDNEENLHASTIDNLNKIIQVFVLEYLHL--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16769-1", "uniprot_id": "QPCT_HUMAN", "id": "Q16769-1", "name": "Glutaminyl-peptide cyclotransferase", "aln": "MAGGRHRRVVGTLHLLLLVAALPWASRGVSP--SASAWPEEKNYHQPAILNSSALRQIAEGTSISEMWQNDLQPLLIERYPGSPGSYAARQHIMQRIQ-RLQADWVLEIDTFLSQTPYG-YRSFSNIISTLNPTAKRHLVLACHYDSKYFS-HWNNRVFVGATDSAVPCAMMLELARALDKKLLSLKTVSD---------SKPDLSLQLIFFDGEEAFLHWSPQDS-LYGSRHLAAKMASTPHPPGARGTS-QLHGMDLLVLLDLIGA--PNPTFPNFFPNSARWFERLQAIEHELHELG--LLK-------DHSLEGRYFQNYSYGG------VIQDDHIPFLRRGVPVLHLIPSPFPEVWHTMDDNEENLDESTIDNLNKILQVFVLEYLHL--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AK24-1", "uniprot_id": "A0A8M3AK24_DANRE", "id": "A0A8M3AK24-1", "name": "Glutaminyl-peptide cyclotransferase", "aln": "MA-----EMSFSSRLLALIGILTTLTS-----CDTIPWQEKKLKHEATTLNSSELSSIVAHTDLDRMWQKDLKSMLVVRYPGSAGSQQVQQHIKSTLS-LLKAGWDVTEDSFYANTPYG-QLPFTNIIATLNPTAKRQLVLACHYDSKYYPPQWDGREFLGAIDSAVPCSMILELSRAQDDELKTLK---N---------SGSDLSLQLLFFDGEEALYQWTSEDS-LYGSRHLAHKMATASHPPEATNTS-QLDSIDLFVLLDLIGG--PNPRFGNQFSSTTRWLSRLRNIERRLHALG--QLE-------NHPNEVQYFWPGLHVG------LILDDHIPFLNRGVRILHLISTPFPAVWHTFDDNEENLDQTSISNLNKILQVFVLEYLNKKSPENQVVEGS---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43599-1", "uniprot_id": "YFI8_YEAST", "id": "P43599-1", "name": "Uncharacterized protein YFR018C", "aln": "---------MGMKYVLPLRLIGLAYLLVLFQVHRVTGWELSYEQYHAAHLN----EAINPDSGWNKSTKNLLLPFNRTRVPGSEGSREIQRFIIEHFNNTLAGEWAVETQAFEEN-----GYRFNNLVMTLQNNASEYLVLAAHYDTKIAP-----TGMVGAIDSAASCAALLYTAQFLTHIACHERTKEYNDLESNTVVSNSTLGVKIVFFDGEEAIEEWGPEDS-IYGARRLAAQWLADG----------TMTRIRLLFLLDLLGSGEEEPLVPSYYAETHQEYQLLNRIEDDLLFRRGDEINGESALAAEVARQRKHLDPTDYRFLGLGHSVIGDDHTPFLAAGVPVLHAIPLPFPSTWHTVDDDFRHLDAAETRHWALLVCEFVVQSLRSRNQ-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VRQ9-1", "uniprot_id": "QPCT1_DROME", "id": "Q9VRQ9-1", "name": "Glutaminyl-peptide cyclotransferase", "aln": "-------MAIGSVVFAAAGLLLLLLPP-------------SHQQATAGNIG-------SQWRDDEVHFNRTLDSILVPRVVGSRGHQQVREYLVQSLN-GLG--FQTEVDEFKQRVPVFGELTFANVVGTINPQAQNFLALACHYDSKYFP---NDPGFVGATDSAVPCAILLNTAKTLGAYLQKEFR------------NRSDVGLMLIFFDGEEAFKEWTDADS-VYGSKHLAAKLASKRSGSQAQLAPRNIDRIEVLVLLDLIGA--RNPKFSSFYENTDGLHSSLVQIEKSLRTAG--QLE----------GNNNMFLSRVSGG------LVDDDHRPFLDENVPVLHLVATPFPDVWHTPRDNAANLHWPSIRNFNRVFRNFVYQYLKRHTSPVNLRFYRT--------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8I936-1", "uniprot_id": "Q8I936_DROME", "id": "Q8I936-1", "name": "glutaminyl-peptide cyclotransferase", "aln": "---------MLGRIALFLTIIYVVFKAMFLR------WVIEKPPFK--------------FDDDEEHFNATLAKLLKPRSVGSKGHAEVQDFIETELK---------RLDFITLKNDFQQGVNITNLVGFWNMRAKFYLMLTCHYDSKKPE-NVTTDEFLAAAEGAVSCAILLNVAKTLRQFLIDRWS------------EKKSVGLAFIFFDGHNSLSSDPYDENELLGATHFIDEEFIPLR------------DMAVAVTLSYIGA--PNQTFLSFFEVTNDLHNLIADIEQDLRKSG------------ELDDCHVLFQKKTHYDK-----DLLDDHIVFDEQDVPVIHVSPHEFPNVLYTPADNVENLHYPTIRNMIKIIRCFVHDFYEKWQYFMKWRQAFAINYDFYDD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : * .: . : .: : : : . : *:: : :. * : .***:* ::.* :.*..*: :* : :.: ::****.::: :. *: :: : : . . :*. : . . : : :* * : : *** * .* ::* . :* . : * :. : :. *. : ", "identical_positions": 28, "similar_positions": 75, "identity": "6.76%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130911-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P14137-1", "uniprot_id": "CP11A_RAT", "id": "P14137-1", "name": "Cholesterol side-chain cleavage enzyme, mitochondrial", "aln": "MLAKGLCLR-SVLVKSCQPFLSPVWQGPG---LATGNGAGISSTNSPRSFNEIPSPGDNGWINLYHFLRENGTHRIHYHHMQNFQKYGPIYREK--LGNMESVYILDPKDAATLFSCEGPNPERYLVPPWVAYHQYYQ-----RPIGVLFKSSDAWRKDRIVLNQEVMAPDSIKNFVPLLEGVAQDFIKVLHRRIKQQNSGKFSGDISDDLFRFAFESITSVVFGERLGMLEEIVDPESQRFIDAVYQMFHTSVPMLNMPPDLFRLFRTKTWKDHAAAWDVIFSKADEYTQNFYWDLRQK-RDFSKYPGVLYSLLGGNKLPFKNIQANIT--EMLAGGVDTTSMTLQWNLYEMAHNL-KVQEMLRAEVLAARRQAQGDMAK-MVQLVPLLKASIKETLRLHPISVTLQRYIVNDLVLR--NYKIPAKTLVQVAS-YAMGRESSFFPNPNKFDPTRWLEK--------SQNTTHFRYLGFGWGVRQCLGRRIAELEMTIFLINVLENFRIEVQSIRDVGTKFNLILMPEKPIFFNFQPLKQDLGSTMPRKGDTV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZ82-1", "uniprot_id": "CP11A_MOUSE", "id": "Q9QZ82-1", "name": "Cholesterol side-chain cleavage enzyme, mitochondrial", "aln": "MLAKGLSLR-SVLVKGCQPFLSPTWQGPV---LSTGKGAGTS-TSSPRSFNEIPSPGDNGWLNLYHFWRESGTQKIHYHQMQSFQKYGPIYREK--LGTLESVYIVDPKDASILFSCEGPNPERFLVPPWVAYHQYYQ-----RPIGVLFKSSDAWKKDRIVLNQEVMAPGAIKNFVPLLEGVAQDFIKVLHRRIKQQNSGNFSGVISDDLFRFSFESISSVIFGERMGMLEEIVDPEAQRFINAVYQMFHTSVPMLNLPPDFFRLLRTKTWKDHAAAWDVIFNKADEYTQNFYWDLRQK-RDFSQYPGVLYSLLGGNKLPFKNIQANIT--EMLAGGVDTTSMTLQWNLYEMAHNL-KVQEMLRAEVLAARRQAQGDMAK-MVQLVPLLKASIKETLRLHPISVTLQRYTVNDLVLR--NYKIPAKTLVQVAS-FAMGRDPGFFPNPNKFDPTRWLEK--------SQNTTHFRYLGFGWGVRQCLGRRIAELEMTILLINLLENFRIEVQNLRDVGTKFSLILMPENPILFNFQPLKQDLGPAVTRKDNTVN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05108-1", "uniprot_id": "CP11A_HUMAN", "id": "P05108-1", "name": "Cholesterol side-chain cleavage enzyme, mitochondrial", "aln": "MLAKGLPPR-SVLVKGCQTFLSAPREGLGRLRVPTGEGAGIS-TRSPRPFNEIPSPGDNGWLNLYHFWRETGTHKVHLHHVQNFQKYGPIYREK--LGNVESVYVIDPEDVALLFKSEGPNPERFLIPPWVAYHQYYQ-----RPIGVLLKKSAAWKKDRVALNQEVMAPEATKNFLPLLDAVSRDFVSVLHRRIKKAGSGNYSGDISDDLFRFAFESITNVIFGERQGMLEEVVNPEAQRFIDAIYQMFHTSVPMLNLPPDLFRLFRTKTWKDHVAAWDVIFSKADIYTQNFYWELRQKGSVHHDYRGILYRLLGDSKMSFEDIKANVT--EMLAGGVDTTSMTLQWHLYEMARNL-KVQDMLRAEVLAARHQAQGDMAT-MLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLR--DYMIPAKTLVQVAI-YALGREPTFFFDPENFDPTRWLSK--------DKNITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRVEIQHLSDVGTTFNLILMPEKPISFTFWPFNQEATQQ---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q8E0-1", "uniprot_id": "A0A8M9Q8E0_DANRE", "id": "A0A8M9Q8E0-1", "name": "Cholesterol side-chain cleavage enzyme, mitochondrial", "aln": "MARWSLSARLDQSVSSLKHLLQVIVTRSG-----RAPAIGLQ-DSTVRPFNEIPGQWRNSLKSVFAFAKMGGLRNIHRIMVHNFNTFGPIYREK--VGFYESVNIIKPEDAAILFKAEGHYPKRLTIDAWTAYRDYRN-----RKYGVLLKDGEDWKSNRIILNKEVISPKVQGNFVPLLDEVGQDFVARVNKKIERSGQNQWTTDLSHELFKFALESVSAVLYGERLGLLLDYIDPDSQRFIDCITLMFKTTSPMLYLPPGLLRPIRSKIWRNHVEAWDGIFNQADRCIQNIYRQLRKNPEGNGKYTGVLASLLMLDKLSIEDIKASVT--ELMAGGVDTTAITLLWTLYELARNP-DLQEEIRAEISAARIASKGDMVQ-MLKMIPLVKGTLKETLRLHPVAVSLQRYITEDIVIQ--KYHIPAGTLVQLGL-YAMGRDHQVFPNPEQYLPSRWVN---------SQN-HYFKSLSFGFGPRQCLGRRIAETEMQLFLIHMLENFRIEKQRQMEVKSMFELILLPEKPIMLTIKPLNSSR------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGZ0-1", "uniprot_id": "C12E1_DROME", "id": "Q9VGZ0-1", "name": "Probable cytochrome P450 12e1, mitochondrial", "aln": "--MLSTQWNANKQIS--RQIYQLCR--------GLAQKATAVNLEEAKPYADIPGPSKLQLIRAFLPGGLYKNLPVHEMFLDMNRQYGSIFRMPSVAG-TDLVLTMNPQDYEVIFRNEGQYPYRRSFEVMDYFKRVHRREVFDGYDGLTSGNGPAWGKMRTAVNPILLQPRNAKLYMTNLVQVSDEFLERIR-IIRDPVTQEMPDDFAVDIRHLVIESICSVALNTHLGLLGEQRNNKDIQKLVLALQDVVELGFQLDIMPAFWKYLPMPNFKKLMRSLDTITDFCYFHIGNALKRIEEDAKAGTLNEIGLETSLLEKLARFDRQTAVIIAMDLLFAGADPTLVTLGGILFSLSKSP-DKQARLLEEIRGILPNKDSSLTIENMRNLPYLRACIKEGIRMYPIGPGTLRRMPHDVVLS--GYRVVAGTDVGIAANYQMANMEQFVPKVREFIPERWLRDESNSHL-VGETATPFMYLPFGFGPRSCAGKRIVDMMLEIAISRLVRNFKIGFDYPIENAFKAQFFVQPNIPFKFKFIERNE--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P82712-1", "uniprot_id": "CCD1P_DROME", "id": "P82712-1", "name": "Probable cytochrome P450 12d1 proximal, mitochondrial", "aln": "MNTLSSARSVAIYVGPVRSSRSASV--------LAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIK-EIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVAQKMLKENQDALEKRRQAG---EKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHP-DKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGLGTMRTCQNDVILS--GYRVPKGTTVLLGSNVLMK-EATYYPRPDEFLPERWLRDPETGKK-M--QVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFVMEPAITFPFKFTDIEQ--------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P21595-1", "uniprot_id": "CP56_YEAST", "id": "P21595-1", "name": "Cytochrome P450-DIT2", "aln": "----------MELLKLLCLILFLTLS-------YVAFAIIVPPLNFPKNIPTIP----FYVVFLPVIFPIDQTELYDLYIRESMEKYG---AVKFFFGSRWNILVSRSEYLAQIFKDEDTFAKSGNQKKIPYSALAAY-----TGDNVISAYGAVWRNYRNAVTNGLQHFDDAPIFKN-----AKILCTLIKNRLLEGQTSIPMGPLS---QRMALDNISQVALGFDFGALTHEKNAFHEHLIRIKKQIFHPFFLTFPFLDVLPIPSRKKAFKDVVSFRELLVKRVQDELVNNYKFEQTTFAASDLIRAHN-----NEIIDYKQLTDNIV--IILVAGHENPQLLFNSSLYLLAKYSNEWQEKLRKEVNGITDPKG-------LADLPLLNAFLFEVVRMYPPLSTIINRCTTKTCKLGAEIVIPKGVYVGYNNFGTSHDPKTWGTTADDFKPERWGSDIETIRKNWRMAKNRCAVTGFHGGRRACLGEKLALTEMRISLAEMLKQFRWSLDPEWEEKLTPAGPLCP-LNLKLKFNENIME-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ** . :* * : .: :* *. . .: . * . * :. . : : :. : :: :: ::.: * . * : . : : . : : : ::. : . : . . : :: .* : . : * ::: . * : *: . : :* :.. : * :* :* . . : . * .: * ** * * * * *.::. : : .::.:*: : . : * : :.: ", "identical_positions": 29, "similar_positions": 94, "identity": "5.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130920-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70628-1", "uniprot_id": "PDE9A_MOUSE", "id": "O70628-1", "name": "High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A", "aln": "MGAGSSSYRPKAIYLDIDGRIQKVVFSKYCNSSDIMDLFCIATG--LPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAVKQVS------------------------------------------------------------EREELIQGVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGL-----KVVEIEKCKSDIKKMREELAARNSRTNCPCKYSFLDN-KKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPITLRRWLLCVHDNYRNN-PFHNFRHCFCVTQMMYSMVWLCGLQEKFSQMDILVLMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAIAFQILARPECNIFASVPPEGFRQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHLTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEY---FMQSDREKSEGLPVAPFMDRDK-VTKATAQIGFIKFVLIPMFET--VTKLFPVVEETMLRPLWESREH-YEELKQLDDAMKELQKK-TESLTSGAPENTTEKNRDAKDSEGHSPPN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8QZV1-1", "uniprot_id": "PDE9A_RAT", "id": "Q8QZV1-1", "name": "High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A", "aln": "MGAGSSSYRPKAIYLDIDGRIQKVVFSKYCNSSDIMDLFCIATG--LPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAVKQVS------------------------------------------------------------EREELVQGVLAQVAEQFSRAFKINELKAEVANHLAMLEKRVELEGL-----KVVEIEKCKSDIKKMREELAARNNRTNCPCKYSFLDN-KKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPITLRRWLLCVHDNYRSN-PFHNFRHCFCVTQMMYSMVWLCGLQEKFSQMDILVLMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAIAFQILARPECNIFASVPPEGFRQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHLTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEY---FMQSDREKSEGLPVAPFMDRDK-VTKATAQIGFIKFVLIPMFET--VTKLFPIVEETMLRPLWESREH-YEELKQLDDAMKELQKK-TENLTSGATENAPEKTRDAKDNEDRSPPN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O76083-1", "uniprot_id": "PDE9A_HUMAN", "id": "O76083-1", "name": "High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A", "aln": "MGSGSSSYRPKAIYLDIDGRIQKVIFSKYCNSSDIMDLFCIATG--LPRNTTISLLTTDDAMVSIDPTMPANSERTPYKVRPVAIKQLSAGVEDKRTTSRGQSAERPLRDRRVVGLEQPRREGAFESGQVEPRPREPQGCYQEGQRIPPEREELIQSVLAQVAEQFSRAFKINELKAEVANHLAVLEKRVELEGL-----KVVEIEKCKSDIKKMREELAARSSRTNCPCKYSFLDNHKKLTPRRDVPTYPKYLLSPETIEALRKPTFDVWLWEPNEMLSCLEHMYHDLGLVRDFSINPVTLRRWLFCVHDNYRNN-PFHNFRHCFCVAQMMYSMVWLCSLQEKFSQTDILILMTAAICHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQILAEPECNIFSNIPPDGFKQIRQGMITLILATDMARHAEIMDSFKEKMENFDYSNEEHMTLLKMILIKCCDISNEVRPMEVAEPWVDCLLEEY---FMQSDREKSEGLPVAPFMDRDK-VTKATAQIGFIKFVLIPMFET--VTKLFPMVEEIMLQPLWESRDR-YEELKRIDDAMKELQKK-TDSLTSGATEKSRERSRDVKNSEGDCA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B2M3-1", "uniprot_id": "A0A8M3B2M3_DANRE", "id": "A0A8M3B2M3-1", "name": "Phosphodiesterase", "aln": "MGSASSAYR--MIYLEVDGRVQKVVFSRFCSPCDIKELFCTATG--VSRNTSISLLDSTGAMVSIDPTMPNNTERSPYKVVPVTGSQLA------------------------------------------------------------DKEELFQNVLTQVAEQFSRAFKINELKTEVTNRLAMLEKRVELEGM-----KVVEIEKCRSDIKKLREEMASRNN-------SSFLEDNKKLTPRRDVPSYPKYHLSQDTVEALKQPLFDVWQWESNEMLSCLEHMYHDLGLVKDFNINPITLKRWLLCIHDNYRNN-PFHNFRHCFCVTQMMYSMIYLCGLQEKFTQVDILILMTAAVCHDLDHPGYNNTYQINARTELAVRYNDISPLENHHCAVAFQIFSQPDCNIFASFDPEAFKQIRQGTITLILATDMARHGEIMDSFKQKVDSFDYNNEEHVTCLKMVLIKCCDISNEVRPMEVAEPWVDCLLEEY---FMQSDREKAEGLPVAPFMDREK-VTKPTAQIGFIKFVLIPMFET--VMKLFPQIEEVMVQPLRESRDK-YEELKQIDDAMNEMQKKKTENLTTGGKKK------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P06776-1", "uniprot_id": "PDE2_YEAST", "id": "P06776-1", "name": "3',5'-cyclic-nucleotide phosphodiesterase 2", "aln": "-MSTLFLIGIHEIEKSQTIVQNEHYFDRVIELQDLDSLMVALYKDRVSPFPNVHNFETGVSIVLYDPSKFQLSVRQLDVLFKRFFPSFN------------------------------------------------------ISAIDHTREENLQRLECVERENSICRNRITRINHWMYHHHDDTPDGINKNSYGTVNGNSVPTQACEANIYTLLLHLNDSKAQHLRKASVPRLIRNIEFMSFLSDPIEKISQEGSHYWNILSTWDFCALSLSTQELIWCGFTLIKKLSKDAKVLIADNKLLLLLFTLESSYHQVNKFHNFRHAIDVMQATWR---LCTYLLKDNPVQTLLLCMAAIGHDVGHPGTNNQLLCNCESEVAQNFKNVSILENFHRELFQQLLSEHWPQLLS-ISKKKFDFISE----AILATDMALHSQYED-------RLMHENPMKQITLISLIIKAADISNVTRTLSISARWAYLITLEFNDCALLETFHKAHRPEQDCFGDSYKNVDSPKEDLESIQNILVNVTDPDDIIKDHPHIPNGQIFFINTFAEVFFNALSQKFSGLKFLSDNVKINKEYWMKHKKPQ---------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . :: *.: . *: .*: :. ..: : : ::* **: : * : .. :** .* : *: :*..:: : :: . :: :. : * : *.::* .: .: . . * :: . . * . . : * * . ..:*:: * : :.*. .. * .* *: :...*:. ******.: * * : ** * . : *:* **: **:.*** ** *..:*:* .::::* ***.* : *:::. :::: . . * * : ******* *.: * : :.* : * ::**..**** .*.:.:: *. : *: : . .*:. * * * * ... :: *: :*: : :. : * .* : : : : : :: *.: ..:: :..: . . .: ", "identical_positions": 90, "similar_positions": 168, "identity": "14.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130924-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M2G0-1", "uniprot_id": "F1M2G0_RAT", "id": "F1M2G0-1", "name": "", "aln": "MPA-----------------------LQSLVTDAFHGKGFHTIEEYLQQRESQ-GPQKYTHLLLHHLDRLINEELDKNEFQNCSLLLKCIQRFFKEDSDQEES---LLIQQGLIPK---MVSWFETMTGFLMTEVLASEALLTNAVEDFLDTALIVSRHSRTGTIQMLDSFILRLGFLVTEGSVKPYIQQEALKTVNCILNAAPREERRKLSSTEGARCLMKELARTILTVGDYSQQVALSEALCRMAVGSWRNELATQWFEDTVLAEAFKEVKNWEFETDCRQFLNFLNNRLGDQRRVYSFPCLAAFADAQEMRKPADEKLEEFWIDFNLGSQSVTFYIDN-AESALWEPVQLLKEAVTKFFIIEN--------ESIKMFIVYLKQPIVISKREAKKIEIYFDRQLDISQASIQALEEDEQAHSFQAS-------------------------------------------------------------------------------------------------------------------------------------------------------------VLIKVSSGLEKEDGEIPSS---------LEGETEDKEESTVLPEFVDAEV----------------------------------DQCLITRRFNVQSVPTVSKGSQEQ-------------------TKSEDCSPENSKPDEPEQVTSEYEYSVDVQDLSIQNQASTLNNTKEESAFARDREQGRRMSFNDRKHYILESNEGSSSNTSERSWTQNHKRKSLRTYSQRRKTRVSS-----------------------------LRILPLSPIRSGRVPE-------------------------------------------------------------------------------------------------------------------------KDEAELT-PLWKGIPRRNNSTPLNISETKLRESSVLLTPEASTQKIGFEMPERRGSEPSSSTKKTGETDGLH----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WREFQSPHSSSSLSSLERPEVEKNEPQIVNCEPFMGNRSSKHKLES------------------------------------------------SEHRETPDGSAVALKQSRLED--APGSPIVAD--------ISTPSQEDVPENTNSSALKMAFENFTRDLKRKFELRLKQREIPLSSEKAKEVPACLIRLWNQIHTCRQDKLEGFHSSVLQELGSLEKDLQTLECLEKDAL-------ASLLFVLSLG-ERTSSRP-----------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0M3U1B0-1", "uniprot_id": "SYC2L_MOUSE", "id": "A0A0M3U1B0-1", "name": "Synaptonemal complex protein 2-like", "aln": "MST-----------------------LQSLIIDGFHGNGFHMIEEYLQQKESH-VPQKYNHLLLHHLDRLIKEELDKNEFQNCSLLLKCIQRFFRDDPDHEEP---LLIQQGLIPK---MVSWFEIITGLLITKVLASEALLTNALEDFLDTALIISRHSRKATVQMLDSFILRLGFLVAEDSVKPSIQQETLATLNCILNAAPQEERRKLSSAEGACCLMKELARTILTVGDYSQQVALSEALCRMSVGRQRNDLAMQWFENTALAEAFKKIKNREFETDCRQFLNFLNNRLGNQRRVYSFPCLAAFADGQEMRKPADEKLEEFWIDFNLGSQSVTFYIDN-AESALWEPVKLLKEAMVKFIIIEN--------DRIKMFIVYLKQPIVISKREAKKIEIHFDRQLGILQASIQALGEDKQAPSFQTS-------------------------------------------------------------------------------------------------------------------------------------------------------------VLVKLFSGLEKEDGEIPGR---------CEREAEDAEESTLLPELVDAEA----------------------------------DRCLITRCFNVQTVPGVSKGSLEI-------------------TNTEERSLENSKQDEPEQVTSEYDYPLDMQEPSIQNQASDLNNIKEDSAFARDREQDRRMPFNDRNHDLLESNEDSSLSTNERSWTQNHKRKSLRTYSQRKKQRVSS-----------------------------LRILPLSPIRSGHAPE-------------------------------------------------------------------------------------------------------------------------KDEAELV-PLWKGISRRNDSTLLKISETKLRGSSVLLTSGASTQKIGLEKPERRGSEPSSSTKKTRVTDGLH----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WREPRSPHPSSGPSSLEYLEVEENIPEIVNRESFMGNSSFKHKLEN------------------------------------------------LGHREIPDGSVAALKQSRLED--APGSPVVTD--------TSTPSQEDMPGSVNGSAFKTAFENFTRDLKRKFELELKQREIPFSLEKAKEAPACLIRLWNQIHTCRLDTLERFHSSVLRELSGLEKNLQTLKCLEKDAL-------ASLLFVLSLGRERTFSR------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T4T6-1", "uniprot_id": "SYC2L_HUMAN", "id": "Q5T4T6-1", "name": "Synaptonemal complex protein 2-like", "aln": "MQAKNKDALQPIKEDRTGKAQDDAFWLQSLITDAFHDKGFQKIKEYFQQKESH-FPQKYNRLLLYRLDRSINKELDKNEFQSVSLLLKCIQRFLVDGLKEDEP---LLIRQGLIPK---LVSWFERTTGILTSEGLASDTSLICVIEDFFDTALIISRSSSEGKIQMLDSFLLSLGFLVTEKTVNHLLQQEGLKTFNCILHAVPREERKKFPLSEGMCHLMKDLARTLLTVGDYDQQVAISEALCRLTIKKSRDELVHKWFDDEVIAEAFKEIKDREFETDSRRFLNHLNNRLGDQRRVYSFPCIAAFADEHEMRKPADEKLEKFWIDFNLGSQSVTFYIDN-AENTLWDSVTLPKEAVMNFSITET--------EKIKIFIIYLKKPMIISYKEVMKIEIHFDLQFNISQVSIQALGEDKQMLPDQTK-------------------------------------------------------------------------------------------------------------------------------------------------------------ISSELFSKSDKEDRESPSG---------LERETEQAEESTNMVEFMSAED----------------------------------DRCLITLHLNDQSEPPVIGEPASD-------------------SHLQPVPP-FGVPDFPQQPKSHY-----------------------------------------RKHLFSESNQDSS--TSELSWTSNQKKKSLKSYSSRKKTRTRSN----------------------------LRILPVFPPSSGSGHE-------------------------------------------------------------------------------------------------------------------------KDQAKLLSPSEKEIPEQNNTTSPKTSEQKFQDSFAFLTAEDSAQKT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELQDPHSLSELSSLKHSEDEEK-PKIVNQESLTESTSLKHKLRN------------------------------------------------LEDKDIPEGSFAKSQQSRLEEEVAPGSPFSITEERELPEGISTSSLEVVPENLNGSAILPTFENFTKKRKRKYELRYRKR--PFNSENAKKAPDCLIKLLNQMQLFRLNKLERFQNLVLQELSSLKQDIQALEHLEKEVLEFWGKQSADLQSFCDLQVLRFNSTQTS---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BX26-1", "uniprot_id": "SYCP2_HUMAN", "id": "Q9BX26-1", "name": "Synaptonemal complex protein 2", "aln": "MPIR-----------------PDLQQLEKCIDDALRKNDFKPLKTLLQIDICEDVKIKCSKQFFHKVDNLICRELNKEDIHNVSAILVSVGRCGKNISVLGQAGLLTMIKQGLIQK---MVAWFEKSKDIIQSQGNSKDEAVLNMIEDLVDLLLVIHDVSDEGKKQVVESFVPRICSLVIDSRVNICIQQEIIKKMNAMLDKMPQDARKILSNQE-MLILMSSMGERILDAGDYDLQVGIVEALCRMTTEKQRQELAHQWFSMDFIAKAFKRIKDSEFETDCRIFLNLVNGMLGDKRRVFTFPCLSAFLDKYELQIPSDEKLEEFWIDFNLGSQTLSFYIAGDNDDHQWEAVTVPEEKVQIYSIEVR--------ESKKLLTIILKNTVKISKREGKELLLYFDASLEITNVTQKIFGATKHRESIRKQGISVAKTSLHILFDASGSQILVPESQISPVGEELVSLKEKSKSPKEFAKPSKYIKNSDKGNRNNSQLEKTTPSKRKMSEASMIVSGADRYTMRSPVLFSNTSIPPRRRRIKPPLQMTSSAEKPSVSQTSENRVDNAASLKSRSSEGRHRRDNIDKHIKTAKCVENTENKNVEFPNQNFSELQDVIPDSQAAEKRDHTILPGVLDNICGNKIHSKWACWTPVTNIELCNNQRASTSSGDTLNQDIVINKKLTKQKSSSSISDHNSEGTGKVKYKKEQTDHIKIDKAEVEVCKKHNQQQNHPKYSGQKNTENAKQSDWPVESETTFKSVLLNKTIEESLIYRKKYILSKDVNTATCDKNPSASKNVQSHRKAEKELTSELNSWDSKQKKMREKSKGKEFTNVAESLISQINKRYKTKDDIKSTRKLKESLINSGFSNKPVVQLSKEKVQKKSYRKLKTTFVNVTSECPVNDVYNFNLNGADDPIIKLGIQEFQATAKEACADRSIRLVGPRNHDELKSSVKTKDKKIITNHQKKNLFSDTETEYRCDDSKTDISWLREPKSKPQLIDYSRNKNVKNHKSGKSRSSLEKGQPSSKMTPSKNITKKMDKTIPEGRIRLPRKATKTKKNYKDLSNSESECEQEFSHSFKENIPVKEENIHSRMKTVKLPKKQQKVFCAETEKELSKQWKNSSLLKDAIRDNCLDLSPRSLSGSPSSIEVTRCIEKITEKDFTQDYDCITKSISPYPKTSSLESLNSNSGVGGTIKSPKNNEKNFLCASESCSPIPRPLFLPRHTPTKSNTIVNRKKISSLVLTQETQNSNSYSDVSSYSSEERFMEIESPHINENYIQSKREESHLASSLSKSSEGREKTWFDMPCDATHVSGPTQHLSRKRIYIEDNLSNSNEVEMEEKGERRANLLPKKLCKIEDADHHIHKMSESVSSLSTNDFSIPWETWQNEFAGIEMTYETYERLNSEFKRRNNIRHKMLS-YFTTQSWKTAQQHLRTMNHQSQDSRIKKLDKFQFIIIEELENFEKDSQSLKDLEKEFVDFWEKIFQKFSAYQKSEQQRLHLLKTSLAKSVFCNTDSEETVFTSEMCLMKEDMKVLQDRLLKDMLEEELLNVRRELMSVFMSHERNANV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IP96-1", "uniprot_id": "A0AC58IP96_DANRE", "id": "A0AC58IP96-1", "name": "", "aln": "------------------------MNFGRRLRDAFVQNNVNMAVVILAEEKSS-------VTLVDRLDDVVIKELHKHEHKNVALILRAIEGLINKDEDCIHK----LVHNGLVAKDFYMLNWFETASEYLKAQPKPP-RDVLKLIEVFYEISMSLCQTTISGSNKILDVFLLRFGAVVLDYEVPFCLRLEAIRTINSMLDSSPKDVRKKLCHSNDHIGLLEDLAKVLTDIGDYEMQVAISEALCRMTPRKLRGDFAGKWFNFRSFASAFTSIRDKDFETDCRTFLNELNSYFGGSSRVFSFPCIQAFLGSTELLKPEDEFLQEFWVDFNLGTSTITFFVKD-PQNTLWELIHLPKDIVRTYDVQVLKMTMLAECDDRKILAVHLTTPICQGGITGKMVKIIFSSVHSIETALLRVFEEKPQSATVSKD--------------------------------------------------------------------------------------------------------------------------------------------------------------------TLQSGDSLTMTK--------------GPQHEQPVIPCIFTSSP--------------------------------------AGKFKSIHRLSLLLSGPRSK-------------------VKGNRCQDIFRFKDHSDSEVARAKTMLFCQTSSSSSSTNG---------------------STKSLPDTLSRTPVKKKMRMTHSDKGSHREGTPQADYHRRKPRAKSK----------------------------LRVLPLSSPSSNE----------------------------------------------------------------------------------------------------------------------------EDFSKLSIPKGVQEMKNMASEDDDWFEHKLEKSFIMQSSSLKDTTADSG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FQNKTVSESSLQADELDLMEEEHILDKALPSQRNEAIESSELHVHLN------------------------------------------------EEAEVPKQPACPPRRPFLSGPLEDAAERVTE---------ALMEGGEESEEELGAGVRKAFNSFKIQLRAHFSSRYKKIE-ARTLQSFTDCQRNVTSLLGTVHNQRLLHLEQFQNTVVHQLECLEQDCLSLKSIEKETVNFWRSESDTVRTFCDRQQNRLHSLLLPDASAQPSSFSVSAQREAKSTVPPSPQEQSPMMVPMSETTTTDL--------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *.: :..: : . :. ::* : .**.*.: :. : :* .: . . ::::**: * :: *** . : :: . : :* : : : : : .. :::: *: : :* : * :: * : ..*.:*. *:: *: : : *:..:.. : ***. **.: *****:: * ::. :**. :*.**. ::: :****.* *** :*. :*.. **::***: ** . *: * ** *::**:*****:.:::*:: . :. *: : : :: : : : : *:: : *. .: . : : *. * . : : : . . :. : .: . : .. . : . . . : : .. . . . . .. .: ::* . * * *. :. .:* .. : * . * : .. . : ... .. . * . : : :: . : :. : ::: :. . : : . . : . :. . : : : * *: *: ::.:* :::: :*: :**: : . . * ", "identical_positions": 89, "similar_positions": 236, "identity": "5.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130925-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8WTX9-1", "uniprot_id": "ZDHC1_HUMAN", "id": "Q8WTX9-1", "name": "Palmitoyltransferase ZDHHC1", "aln": "-------------------------MYKMNICNKPSNKTAPEKSVWTAPAQPSGPSPELQG-------------------------------------QRSRRNGWSWPPHPLQIVAWLLYLFFAVIGFGILVPLLPHHWVPAGYACMGAIFAGHLVVHLTAVSIDPADANVRDKSYAG-PLPIFNRSQHAHVIEDLHCNLCNVDVSA-RSKHCSACNKCVCGFDHHCKWLNNCVGERNYRLFLHSVASALLGVLLLVLVATYVFVEFFVNP-------------------------------MRLRTNRHFEVLKNHTDVWFVFLP--------------------------------------AAPVETQAPAILALAALLILLGLLSTALLGHLLCFHIYLMWHKLTTYEYIVQHRPPQEAKGVHR-----------------------------------------------------------------------------------------------------------ELESCPPKMRPIQEMEFYMRTFRHMRPE------------------------------------------------PPGQAG-------------------------------PAAVNAKHSRPASPD----------------------PTPGRRDCAGPPVQVEWDRKK-----PLPWRSPLLLLAMWGPQAPPCLCRKRGRGACIKCERLRPRIRRRGLG-------PPAAAPARRRIP-------RTPALCTPLALPAPTTRRRQSPWTRFQ------------WRRRAWAAPLWPPRGAGADSPRWRGRRVRPPFS---------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F7F2Z1-1", "uniprot_id": "F7F2Z1_RAT", "id": "F7F2Z1-1", "name": "Palmitoyltransferase", "aln": "----------------------------MNICNKPSNKTAPEKNVWTAPSQDSGPSPELQG-------------------------------------QRSRRNGWSWPPHPLQIVAWLLYLFFAVIGFGVLVPLLPHHWVPAGYACMGAIFAGHLVVHLTAVSIDPADANVRDKSYSG-PLPIFNRSQHAHVIEDLHCNLCDVDVSA-RSKHCSACNKCVCGFDHHCKWLNNCVGERNYRLFLHSVASALLGVLLLVLVATYVFVEFFVNP-------------------------------MRLRTNQHFEVLKNHTDVWFVFLP--------------------------------------AAPVETQAPAILALAALLILLGLLSTALLGHLLCFHIYLMWHKLTTYEYIVQHRPAQEAKETHK-----------------------------------------------------------------------------------------------------------ELESCPRKMRSIQEMEFYMRTFSHVRPE------------------------------------------------PSGQAR-------------------------------PAALNAKKG-----------------------------TSSRRDSGAASRVCSLAFTS-----VLP--SFLPHKAKWNHHCPP----PQTHWLCLHGSNP----RKRGSG-------EYIDCPG----------------------LGPWTESSGCPSYVTLG------------LLAATLALPLIPPVPA---------QHMLVAL----------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0N9-1", "uniprot_id": "ZDHC1_MOUSE", "id": "Q8R0N9-1", "name": "Palmitoyltransferase ZDHHC1", "aln": "----------------------------MNICNKPSNKTAPEKSVWTAPSQDSGPSPELQG-------------------------------------QRSRRNGWSWPPHPLQIVAWLLYLFFAVIGFGVLVPLLPHHWVPAGYACMGAIFAGHLVVHLTAVSIDPADANVRDKSYSG-PLPIFNRSQHAHVIEDLHCNLCDVDVSA-RSKHCSACNKCVCGFDHHCKWLNNCVGERNYRLFLHSVASALLGVLLLVLVATYVFVEFFVNP-------------------------------MRLRTNQHFEVLKNHTDVWFVFLP--------------------------------------AAPVETQAPAILALAALLILLGLLSTALLGHLLCFHIYLMWHKLTTYEYIVQHRPAQEAKETHK-----------------------------------------------------------------------------------------------------------ELESCPRKVRSIQEMEFYMRTFSHVRPE------------------------------------------------PSGQAR-------------------------------TAALNANPSQFLATQGQV-----------------EPPLPSSSDTLALPPRIQPQKKRKRRVYRLP-RSGVLDRELPLPRLRETGTPSRRSSSSSDSTSASPVHAGGSAG-------AYYSASAES-----------------MEEIPVAQTRLGSAALGAPG------------ARGRESGLALQARSPAVFVSPSSGEPGTPGGGDGLP------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F4Z4-1", "uniprot_id": "ZDHC1_DANRE", "id": "E7F4Z4-1", "name": "Palmitoyltransferase ZDHHC1", "aln": "----------------------------MDVCSKNSNRTAP--------VSEGGIRRADVP-------------------------------------LCSRTNGWSWPPHPFQFLAWLLYLYFAVTGFGVFVPLLPTHWIPAGYICTGITFVCHLFMHLMAVSIDPADYNVRAKSYKG-PMPVFDRTKHAHVIENCHCYLCEVDVGP-KSKHCSACNKCVASFDHHCRWLNNCVGSRNYWLFLNSVISALLGIVLVVVIASYVFIEFFLDP-------------------------------SKLRSDKHFQQVRNESVVWFVFLP--------------------------------------VAPVTTAGPAIPALAGVTIALGLLSALLLGHLLCFHIYLMWNRLSTYEYIVRQRHRQEAGDSRKPP--------------------------------------------------------------------------------------------------------PENDSGVPKLNLIKQQVSYSGTLGYTNPEMEVEDPKAMTSQEGAARYGNGRIRCSSEHMDEEEHLPSVLTEQKASPHPHKHAQKK----------------------KRKVRKLAAEVNGDISIDTSTAKG------------------LQKTSAEKESSVAAATVSSSLGQRLPFPAFPLRASLPPLAPVQAAGPPAEYHSDSAESLEEIPVAMARLGSAALAG---AQIPTTTATASSSYSSMLQCALPSSAAGHAAPSPQPRTKRKTAARTVSEQRFEMLYHNPSMFMTRESGEPAIPPEESPRAAKRKQTGKKRNTEDAKPSSRVGTSLA---------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPM2-1", "uniprot_id": "Q9VPM2_DROME", "id": "Q9VPM2-1", "name": "Palmitoyltransferase DHHC domain-containing protein", "aln": "MSTTAAGLKSGPKGAYGVRSETDHIITISTAGLTESHSESPAKGVVTPVRKPHSLGSEDSPENIIPGEQAETNKKPLHLCRLSQLVSYQSNIADVQHRKGRRLHGLQLPLHPLQIFGWLVLLLFGVASYWVLIPAFHARIQGPLYGLITGLYLVHIASHLTALLTDPADKELRRVHRNDRIVPEFDRSKHSHVIENGRCHLCNIRTSSNRTKHCSVCNKCVGKFDHHCKWLNHCIGSRNYVAFLMCVVSAVVATLVIVAAVVAQIVFYYIQPDWLSFYWCPTESSHTIESGDFINITLSLSNGTMMLIEQHTSEEDVHQEMWDEEQANMTISTLPTLLENFTAIIEASATRPGISPTNHTETQPVVTGIGLNETIFMFLLGVLGLLAAVSAGLLLHLCFFHIYISFLGLTTYEYIRNHRQAQDAKTKQLLEGAPGVRAPKNGNVHFSASLPEPHNPSKSLPGGQQLYCCSSAPHPSQHSQESVGQTEQSLRLHCCASSREFHQSGQAIYVCSLLEEAVPQIQVEPDTLSSFHCCSSFAASSLQRRVSLAKGSLISAEPRHLRPATYLQYTEQCTLCTFRLRRGSGPGTGSSGAVSSAGGSSSTRTLTSQTGGSSASATAAGNISKHQRWRRKWNCCAAVPDSPDLPNDLLAALTFRESEEAAAAAKLNAQELPIQFIRTLNGGLDQELPLKATTATPTPPRSSRLRYMLRLLGRYRRPRCRHGAHHGIAAKEHQNIGGSAIKQNQIRPLQLQAAGRGYANSTATPTPPASSPSRSSLESSDLSTSTSPSCGKKELMLLPTSVIRDDSVTTYTLTLPPALPPPTRRKMNQTTQELAELAETLGFASNLQHSQHNSQTNSRTLPSFGNVYRRQRRKHFLRTRSPTLSPIHESGLSNPTSPQPLRHHHQNLANSNSNPAKAMSSPMLNRNSGSANSSALLVQNLCSLAGETLRNSASNSSLQSLSSNSSST", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *: :* . . * :* . * **:*:..**: * *.* .: :::* : : . * : *: ** *: **** ::* . :* *:*::*:****: :* **:: ... ::****.***** *****:***:*:*.*** ** .* **::. :::* . :: ::::* : ::* . . :* . .: : . : * .: *. :*: ** ** ****: : *:***** .:* *:* : * : : : : .* . * * :. . . . . . . . . ... . : ", "identical_positions": 90, "similar_positions": 105, "identity": "9.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-130925-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZMC4-1", "uniprot_id": "A0A8I5ZMC4_RAT", "id": "A0A8I5ZMC4-1", "name": "", "aln": "VAPKPKVTTNPSTPPAKFPASQRPNSFPSPNSMSRGPKPPIAPKPRLAGPSEYGAGVYLNNSLSKCSNGRLLCEDPSLYDGHHSTLNCLELETDEQYIMVPRAPQRDDALTDRATEKQGFEGEAQEHGTEQTGTERDLAAPDEEAPSRDSEEGVDHALEDEEDCDHDLETDGTPTAPGEGAPSRDGEKGEEDCGQDPGVEEHPMSEEEGEEEEAKECVHNRDDRAPWDGGEPFLNEVVLTHVCSQSPEVPCWEPGLPETPGEVDEDSEDICNNTELG---------KPNQDTGQDTEDASMGSPESEVSPDVQEQEAATDSPEVFEE--DSVDAAEGEDQIARDEPPNCEEDTNNRETAAATMQAGEDHGEDGDRVQEDPAEENCQIIPFESDSVEEDCSPTLTENPYELFPTESTSFCNNSGS-LAESDKGQES----VCKICVEEVPGIGPSLSQGDSLQDGSGEEAP-VPEVVVVPENEDPMDDALSSPYVMGVGLLSLGEGAQSDTQAASGTLSGYSTWEEG--DSDGGQVPVDRKNIATRARPHSGKVAGHVPETVLEETGPEACSSAMGIRDTGDEVRKIGILPEGKPSESLRALPAKPRAFTLYPRSFSVEGRESPLSMFREPEGAGLDMHRVRRKEDNLSLPGAIGSSGSFSQRSHLPSSGTSTPSSVVDIPPPFDLACITKRPITKSSPSLLIDGDTLEKASKKKKSSFKR-FLELTFRKKTESKVHVDMSLSSSRSSSESSYHGPARVLELDRRSLSNSPQLKCHTGKLRASDSPASLIFYRDSKRKGVPFSR-TVSRVESFEDRSRPPFLPLPLTKPRSISFPNADTSDYENIPAMNSDYENIQIPPRRPARTGTFTKLFEEQSRALSTANENDGYVDMSSFNAFESKQQSSEQEAESAYTEPYKVCPIS-TTPKEDLTSDEEQGSSEEEDNASRDPSLSHKGEGQSRAFVIAQELLSSEKAYVQMLQHLSLDFHGAVLRALENVEQEGREPLAQEELRQGLRELPAICDLHQGILESLEQRLGDCGEGQQQVADIFLAREQEFEHHAAHILQFDRYLGLLAESCLLSPRLATTVREFEQSSQGGGQSMKHRMLRVVQRLFQYQVLLTDYLNNLCPDSAEYDNTQSNEGVTISCACPQ-------ENLQKLVHIEYSVRGQGDLLQPGREFLKEGTLMRVRGKSRHPRHLFLMNDTLLYTHPQKDGKYRLKSSLPVANMKVSRPVMDKVPYALKIETPESCLTLSASSCAERDEWHYCLSRALPEDYKTQALAAFHHSVEIRERLGISLGERLPTLVPVTHAMMCMNCGCDFSLTVRRHHCHACGKIVCRNCSRNKYPLKCLKNRMAKVCDGCFRELKLRNGPVPGPIRERPVSMSFPLSSSRFSSGSTFSSVFQSISPSTFKKQKKVPSALAEVAASGEGSAISGYLSRCKSGKRRWKKLWLVIKGKVLYTYLASEDKVAMESIPLLGFTIAPEKEEGSSEVGPVFHLYHKKTLFYSFKAEDSSSAQRYQQQIAFYFLVCLAEKCRLALHCSMQAPGGPSTAAGLHVLSHET", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80UZ0-1", "uniprot_id": "FGD5_MOUSE", "id": "Q80UZ0-1", "name": "FYVE, RhoGEF and PH domain-containing protein 5", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSPESEVSPDVQEQEAATDNPEVFEE--DSADAAEGEDQIEQEEPPNCDEEAYNRDAAAATMQVGEDLGEEGDHVQEDPAEESCQIIPFESDSVEEDFSPTLTENPYEIFPTESTSFCNNTYS-LDESANGHEP----VCEICVEEVPGVGPPLNQHDSLPDGSGEDSPVVPDVVVVPENEGPVDDALSSPYVMGVGLLSLGEGAQSDTQAASGTLSGYSTWEEG--DSEGGQVPVDRKNIATRARPHSGKVAGHVPETVLEETGPETCSSGMGIRDTSDEVRKIGILPEGKPPECVRALPAKPRAFTLYPRSFSVEGRESPLSMFREPEGAGLDSHRVRRKEDNLSLPGAIGSSGSFSQRSHLPSSGTSTPSSVVDIPPPFDLACITKKPITKSSPSLLIDGDTLEKASKKKKSSFKR-FLELTFRKKTESKVHVDMNLSSSRSSSESSYHGPARVLELDRRSLSNSPQLKCRTGKLRASDSPAALIFYRDSKRKGVPFSR-TVSRVESFEDRSRPPFLPLPLTKPRSISFPNADTSDYENIPAMNSDYENIQIPPRRPVRTGTFTKLFEEQSRALSTANENDGYVDMSSFNAFESKQQSSEQEAESAYTEPYKVCPIS-AAPREDLTSDEEQGSSEEEDSASRDPSLSHKGEGQSRALVIAQELLSSEKAYVQMLQHLSLDFHGAVLRALENVEQEGREPLAQEELRQGLRELPAICDLHQGILESLEQRLGDCGEGQPQVADIFLAREQEFEHHAAHILQFDRYLGLLAESCLLSPRLATTVREFEQSSQGGGQSMKHRMLRVVQRLFQYQVLLTDYLNNLCPDSAEYDNTQSALTLISKVTDRANESMEQGENLQKLVHIEYSVRGQGDLLQPGREFLKEGTLMRVRGKSRHPRHLFLMNDTLLYTHPQKDGKYRLKSSLPVANMKVSRPVMDKVPYALKIETPESCLTLSASSCAERDEWHYCLSRALPEDYKTQALAAFHHSVEIRERLGISLGERLPTLVPVTHAMMCMNCGCDFSLTVRRHHCHACGKIVCRNCSRNKYPLKCLKNRMAKVCDGCFRELKLRNGPVPGSMRERPVSMSFPLSSSRFSSGSALSSVFQSISPSTFKKQKKVPSALSEVAASGEGSAISGYLSRCKSGKRRWKKLWLVIKGKVLYTYLASEDKVAMESIPLLGFTIAPEKEEGSSEVGPVFHLYHKKTLFYSFKAEDSNSAQRWMEAMEDASVL---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZNL6-1", "uniprot_id": "FGD5_HUMAN", "id": "Q6ZNL6-1", "name": "FYVE, RhoGEF and PH domain-containing protein 5", "aln": "--------------------------------MFRGPKPPIAPKPRLTAPNEWRASVYLNDSLNKCSNGRLPCVDRGLDEGPRSIPKCSESETDEDYIVVPRVPLREDEPKD-----EGSVGNKALVSPESSAEE------EEEREEGGEACGLEGTGAGEDSVAPAAPGAGALSREGEEGTDLALEDEGEGCADEPGTLEQVSRSEEEEKLVQPHRECSLEDSGPWAGEGVFQSDLLLPHIHGEDQEP-------PDTPGEAEEDDEEGCASTDPAGADEGSGPDRPTEDMGQDAEDTSEEPPEKEELAGVQEAETATDCPEVLEEGCEEATGVTGGEQVDLSEPPDHEKKT-NQEVAAATLED---------HAQDESAEESCQIVPFEND-CMEDFVTSLTGSPYEFFPTESTSFCSESCSPLSESAKGLESEQAPKLGLRAEENPMVGALCGQCGSLQGG-AAEGPAAPDVVVVLEEEA-LDDALANPYVMGVGLPGQAAPGEGG-QAASDALGGYGSKEELNCEAEGGLVPADRKNTSTRVRPHSGKVAGYVPETVPEETGPEAGSSAPGIGGAAEEVGKTLLSLEGKPLEASRALPAKPRAFTLYPRSFSVEGREIPVSVYQEPEGSGLDDHRIKRKEDNLSLSCVIGSSGSFSQRNHLPSSGTSTPSSMVDIPPPFDLACITKKPITKSSPSLLIESDSPDKY-KKKKSSFKR-FLALTFKKKTENKLHVDVNVSSSRSSSESSYHGPSRILEVDRRSLSNSPQLKSRTGKLRASESPSSLIFYRDGKRKGVPFSR-TVSRVESFEDRSRPPFLPLPLTKPRSISFPSADTSDYENIPAMNSDYENIQIPPRRPARAGAFTKLFEDQSRALSTANENDGYVDMSSFNAFESKQQSADQDAESAYTEPYKVCPISSAAPKEDLTSDEEQRSSEEEDSASRDPSVTHKVEGQSRALVIAQELLSSEKAYVEMLQHLNLDFHGAVMRALDDMDHEGRDTLAREELRQGLSELPAIHDLHQGILEELEERLSNW-ESQQKVADVFLAREQGFDHHATHILQFDRYLGLLSENCLHSPRLAAAVREFEQSVQGGSQTAKHRLLRVVQRLFQYQVLLTDYLNNLCPDSAEYDNTQGALSLISKVTDRANDSMEQGENLQKLVHIEHSVRGQGDLLQPGREFLKEGTLMKVTGKNRRPRHLFLMNDVLLYTYPQKDGKYRLKNTLAVANMKVSRPVMEKVPYALKIETSESCLMLSASSCAERDEWYGCLSRALPEDYKAQALAAFHHSVEIRERLGVSLGERPPTLVPVTHVMMCMNCGCDFSLTLRRHHCHACGKIVCRNCSRNKYPLKYLKDRMAKVCDGCFGELKKRGRAVPGLMRERPVSMSFPLSSPRFS-GSAFSSVFQSINPSTFKKQKKVPSALTEVAASGEGSAISGYLSRCKRGKRHWKKLWFVIKGKVLYTYMASEDKVALESMPLLGFTIAPEKEEGSSEVGPIFHLYHKKTLFYSFKAEDTNSAQRWIEAMEDASVL---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7J8-1", "uniprot_id": "A0AB13A7J8_DANRE", "id": "A0AB13A7J8-1", "name": "", "aln": "-------------------------------------------MPDDVRQEGQSFRSIRRASEDTSRLSHLSLKIVGIIKNPKHKQHSNISVQKKMYFNMLHNSKSLSSPNS-----------------------------REQTPKVHRKIVVEHKGSQERRTNKIVYPERRLQVDETEVEIILEQGDELGCGDELAHGVDLDLAEGLEKDKPLESED--DEVSVDLHSDLYSKKEVDYNIVAEELQVK-----------------------------------DMGKAAWGLTKNGKNKSSRNVQLASNAVYESLAHADRLLFDKMCTGKTLIESFYPSGIVADRMFSSEEDIDVMFPDICDAG-------EALADKDGLSECDLFEQTEPLQLTETKDNINGDIMMLTIEEGLNSSDLSSVEEEYDEMQMEK---ELMEEQINKSVAGNKAAIPSNSEESDHPSNSSSSSQTCVLSGSDTTLDEITNNNYNSKN--MTESDEAISAILNLVLVQQQPETQDQNSQQYQDEESNGEDKEEQVVDNLSESEGKELMVDNVYEETEPKIQAKDFLQNRKYFMSRSISVETPGKRADLLSGLPAGNGRLLLHPQAFYTD-----QCLFGD------------------SRPALTGSLGCLSQG------TRTSKVTRVDIPPPFELASITKRPIRKSSPSIPN---EISASCKKPDFGFKRYLLPLRFLRKSDRKSMMDTRSISSRSSSESSPQGSCRRMDFIRHNMG-SPELQRSP-DCTPPVSPSSFLSHRNRRKEGLNFSLNNDLACSSISIEPGFLSEPLPLSKPRSFSSPNTDSSEYENVQNVASHYENVQIRLLNPVIQG---------QRNQSSPSDTDGYVDMSSLPGFQGKSQSSEQETDSLYTFCSPNVRADGTVGVFVGVACAQEKKTTAPDKLTVS---------CSRAFYSAKELLDSEAQHVKTLQLLYESVN------------------ADERLMTVWTEVPDICTLHQDIHTLLETRLKEWDQNEG-IAEIILAKKTEFSIFSSYISHYDDKLNYLEH---------------IQSTLSDSVTLKKQLLQVIVRILQYRMLLTDYLNNLSPDSREFENTQDALVVVSDVAYHASDSLKNGADLMRLVHIEHSVLGLTDLIQPGRVFVKEGTLMKVSRKCKQPRHLFLMNDIMLYTYPQQDGKYRLINRLPLAGMKVSKPPMESAQSAIKIEVKDISITLSASSCIERDGWFVTMNRTLVDLG--SASGDPVDSFELVESPEKCLGENAPPLLSVSQVTVCMNCPSHFSLTNRRHHCHACGKVVCRDCCRNKFPLKYMKNRRAKVCDHCYTELRKND-----------------VATVIEGSSRPLSAVFQNIHPSSLWRSRKGQLTFNQVTGSE--GVMSGTLQRCRNSKRSWRSLWFLLKDKVLYTYPQPEERVACETLPLLGFSVRSEAEGESS----VFQLYHKSTLFYTFRAQDSHTAQRWVNAMEEATVF---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : ... . * :::: . ... . : :. . ..*::. . : .:. . : *. . .. : . * :: . .* .. :.. .:. *: .: :*: . * . . . . : :: : :. : *: . . ..: : :.* *** *: :. . : ** : .*** : *:*::* .: .:: : * . ** *.:** :: : *******:**.***:** *****: . ** . .*** :* * * :*:: * :* ********* :*..* ::. *:.:. **:*: . . .. **:::: :*: :::*: ** . .*:. .. ****:****:* *.:*:*:***: : *.***:** .*. * .* *:..:.********: .*:.*.**::*:::* ** . :. .: :: .: *. : . ***: *:***.** :*: ** * ..: * *.* *:* * ***.* ** ** : :.: :*:::**:: *. .:::* ::* *. * . ** ... : *:::*:*: *::**::*********.*** *::***. : . : :* :*****:** * **:**** *:******:* * ::********* :***:**:****** . *.:*.****:* *:.. *:***. : .: ****** *** *. :.*:* : .* . .*.*: * .***. *.*:.*::. :**** ..**** **********:***:*.***:*** :*:* ***** *: **: .. ::: . . .:*:***.* **:: :.:* :: :*:.* ..:** *.**: .** *:.**:::*.****** .*::** *::*****:: .* * ** :*:****.****:*:*:*: :***: : : :. ", "identical_positions": 352, "similar_positions": 340, "identity": "22.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-131001-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q02563-1", "uniprot_id": "SV2A_RAT", "id": "Q02563-1", "name": "Synaptic vesicle glycoprotein 2A", "aln": "MEEGFRDRAAFIRGAKDIAKEVKKHAAKKVVKGLDRVQDEYSRRSYSRFEEEEDDDDFPAPA-DGYYRGEGAQDEEEGGASSDATEGHDEDDEIYEGEYQGIPRAESGGKGERMADGAPLAGVRGGLSDGEGPPGGRGEAQRRKDREELAQQYETILRECGHGRFQWTLYFVLGLALMADGVEVFVVGFVLPSAEKDMCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSSFVQGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAMAWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFLENGKHDEAWMVLKQVHDTNMRAKGHPERVFSVTHIKTIHQEDELIEIQSDTGTWYQRWGVRALSLGGQVWGNFLSCFSPEYRRITLMMMGVWFTMSFSYYGLTVWFPDMIRHLQAVDYAARTKVFPGERVEHVTFNFTLENQIHRGGQYFNDKFIGLRLKSVSFEDSLFEECYFEDVTSSNTFFRNCTFINTVFYNTDLFEYKFVNSRLVNSTFLHNKEGCPLDVTGTGEGAYMVYFVSFLGTLAVLPGNIVSALLMDKIGRLRMLAGSSVLSCVSCFFLSFGNSESAMIALLCLFGGVSIASWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLGISIFTSFVGITKAAPILFASAALALGSSLALKLPETRGQVLQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIS5-1", "uniprot_id": "SV2A_MOUSE", "id": "Q9JIS5-1", "name": "Synaptic vesicle glycoprotein 2A", "aln": "MEEGFRDRAAFIRGAKDIAKEVKKHAAKKVVKGLDRVQDEYSRRSYSRFEEEDDDDDFPAPA-DGYYRGEGAQDEEEGGASSDATEGHDEDDEIYEGEYQGIPRAESGGKGERMADGAPLAGVRGGLSDGEGPPGGRGEAQRRKDREELAQQYETILRECGHGRFQWTLYFVLGLALMADGVEVFVVGFVLPSAEKDMCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSSFVQGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAMAWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFLENGKHDEAWMVLKQVHDTNMRAKGHPERVFSVTHIKTIHQEDELIEIQSDTGTWYQRWGVRALSLGGQVWGNFLSCFSPEYRRITLMMMGVWFTMSFSYYGLTVWFPDMIRHLQAVDYAARTKVFPGERVEHVTFNFTLENQIHRGGQYFNDKFIGLRLKSVSFEDSLFEECYFEDVTSSNTFFRNCTFINTVFYNTDLFEYKFVNSRLVNSTFLHNKEGCPLDVTGTGEGAYMVYFVSFLGTLAVLPGNIVSALLMDKIGRLRMLAGSSVLSCVSCFFLSFGNSESAMIALLCLFGGVSIASWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLGISIFTSFVGITKAAPILFASAALALGSSLALKLPETRGQVLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L0J3-1", "uniprot_id": "SV2A_HUMAN", "id": "Q7L0J3-1", "name": "Synaptic vesicle glycoprotein 2A", "aln": "MEEGFRDRAAFIRGAKDIAKEVKKHAAKKVVKGLDRVQDEYSRRSYSRFEEEDDDDDFPAPS-DGYYRGEGTQDEEEGGASSDATEGHDEDDEIYEGEYQGIPRAESGGKGERMADGAPLAGVRGGLSDGEGPPGGRGEAQRRKEREELAQQYEAILRECGHGRFQWTLYFVLGLALMADGVEVFVVGFVLPSAEKDMCLSDSNKGMLGLIVYLGMMVGAFLWGGLADRLGRRQCLLISLSVNSVFAFFSSFVQGYGTFLFCRLLSGVGIGGSIPIVFSYFSEFLAQEKRGEHLSWLCMFWMIGGVYAAAMAWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVFAIGALTTQPESPRFFLENGKHDEAWMVLKQVHDTNMRAKGHPERVFSVTHIKTIHQEDELIEIQSDTGTWYQRWGVRALSLGGQVWGNFLSCFGPEYRRITLMMMGVWFTMSFSYYGLTVWFPDMIRHLQAVDYASRTKVFPGERVEHVTFNFTLENQIHRGGQYFNDKFIGLRLKSVSFEDSLFEECYFEDVTSSNTFFRNCTFINTVFYNTDLFEYKFVNSRLINSTFLHNKEGCPLDVTGTGEGAYMVYFVSFLGTLAVLPGNIVSALLMDKIGRLRMLAGSSVMSCVSCFFLSFGNSESAMIALLCLFGGVSIASWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLGISIFTSFVGITKAAPILFASAALALGSSLALKLPETRGQVLQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F6Z2-1", "uniprot_id": "E7F6Z2_DANRE", "id": "E7F6Z2-1", "name": "Synaptic vesicle glycoprotein 2A", "aln": "MDEGYRDRSAFIKGAKDIAKEVKRHAGKKVGRHVDKMTDEYTKRSYTRFEEDDDDDDYPVQAQDGSYYRSNSRANDDEGAHSDSTEGHDEDDEIYEGEYQGIPRNDSVEKADRQVGAVGQSQFR-DMTQYEG--------ERRKDQEELAQQYETILQECGHGRFQWTLYFVLGLALMADGVEIFVVGFVLPSAEKDMCLSEPNKGMLGLIVYLGMMVGAFVWGGLADRIGRRQTLLISLSINSVFAFFSSFVQGYSSFLFCRLLSGVGIGGSIPIVFSYYSEFLAQEKRGEHLSWLCMFWMIGGIYAAAMAWAIIPHYGWSFQMGSAYQFHSWRVFVLVCAFPSVAAIAALTTMPESPRFYLENGKHDEAWMILKQVHDTNMRAKGYPERVFSVTTIKTVKQMDELVDMGGEATAWHQRWRIKLTNLFHQVWGNFLTVFNPEYRRITYMMMAVWFSMSFSYYGLTVWFPDMIKYLQKQEYSSRTKVFIKEKVEHVTFNFTLENQIHRNGEYFNNKFLNLKMKSMVFEDSLFEECYFEDITSSNTFFRNCTFISTLFYNTDLFKYRLINSKLINSTFLHNKEGCMLDFSDE-NNAYMIYFVSFLGTLAVLPGNIVSALLMDKIGRLRMLAGSSVISCVSCFFLSFGNSESAMIALLCLFGGISIASWNALDVLTVELYPSDKRTTAFGFLNALCKLAAVLGISIFQSFVGITKAVPILFASGALAAGSFLALKLPETRGQVLQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:**:***:***:**********:**.*** : :*:: ***::***:****::****:*. : ** * ..:: ::: ** **:******************** :* *.:* .... : .* .::: ** :***::********:**:*************************:*****************:.******************:*******:**** ******:**************.:**********************:************************:**************************************** **.**** ******:***********:*************:******** ***::* ***::: .:: :*:*** :: .* *******: *.******* ***.***:****************::** :*::***** *:****************.*:***:**:.*::**: *************:*************.*:*******:*:::**:*:*********** **.:. :.***:************************************:**************************:******************************************* ********.******.*** ** **************", "identical_positions": 582, "similar_positions": 108, "identity": "78.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-131002-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z7Q2-1", "uniprot_id": "SIM20_MOUSE", "id": "D3Z7Q2-1", "name": "Small integral membrane protein 20", "aln": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLMRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N5G0-1", "uniprot_id": "SIM20_HUMAN", "id": "Q8N5G0-1", "name": "Small integral membrane protein 20", "aln": "--MSRNLRTALIFGGFISLIGAAFYPIYFRPLMRLEEYKKEQAINRAGIVQEDVQPPGLKVWSDPFGRK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q9H3-1", "uniprot_id": "A0A2R8Q9H3_DANRE", "id": "A0A2R8Q9H3-1", "name": "", "aln": "--MSSSKRITLIFGGFVAAVAAAFYPIFFHPLTHSEDYKQVQKVNRAGVNQADIQPVGVKVWSDPYKPKS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * :******:: :.******:*:** : *:*:: * :****: * *:** *:******: * ", "identical_positions": 35, "similar_positions": 18, "identity": "50.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-131003-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JSU2-1", "uniprot_id": "A0A0G2JSU2_RAT", "id": "A0A0G2JSU2-1", "name": "Adhesion G protein-coupled receptor A3", "aln": "MERPP---------LLLPLALLALL----WGGERGAVALPAGCKHDGRARGTGRAAG-AEGKVVCSSLELAQVLPPDTLPNRTVTLILSNNKISELKNGSFSG-LSLLERLDLRNNLISRIAPGAFWGLSSLKRLDLTNNRIGCLNADVFRG-LTNLVRLNLSGNLFTSLSQGTFDYLGSLRSLEFQTEYLLCDCNILWMHRWVKERNITVR-DTRCVYPKSLQAQPVTGVKQELLTCGPPLELPSFYMTPSHRQVVFEGDSLPFQCMAS-----------YIDQDMQVLWYQDGRIVETDESQ------------GIFVEKSMIHNCSLIASALTISNIQAGSTGNWGCHIQTKRGNNTRTVDIVVLESSAQYCPPERVVNNKGDFRWPRTLAGITAYLQCTRNSHSSGVYPGNTQDERKAWRRCDRGGFWADDDYSRCQYANDVTRVLYMFNQMPLNLT---NAVATARQLLAYTVEAANFS---DKMDVIFVA-EMIEKFGRFTKEEKSKELGDVMVDVASNIMLADERVLWLAQREAKACSRIVQCLQRIATHRLASGAHVYSTYSPNIALEAYVIKAAGFTGMTCSVFQKVAASDRTGLSDYGRRDPDGNLDKQLSFKCNVSSTFSSLALKNTIMEASIQLPSSLFSPKQKREVRATDDSLYKLQLIAFRNGKLFPATGNSTKLADDGKRRTVVTPVILTKIDGVTTDTHHVPVN-------VTLRRIAHGADAIAAQWDFDLLNGQGGWKSDGCCILYSDENITTIQCGSLGNYAVLMD---LTGSELYTPAASLLHP--VVYTTAITLLLCLLAVIISYMYHHSLIRISLKSWHMLVNLCFHIFLTCVVFVGGITQTRNASVCQAVGIILHYSTLATVLWVGVTARNIYKQVTKKAKR----CQDPDEPPAPPR---PMLRFYLIGGGIPIIVCGITAAANIKNYGSRPSAPYCWMAWEPSLGAFYGPASFITFVNCMYFLSIFIQLKRHPERKYELKEPAEEQQRLAAN--------------------------------ENGEIN---PQDSMSLSLISTSTLENEHSFQSQLLGASLTLLLYITLWMFGAMAVSLDYPLDLVFSFFFGASCLSFSAFIMVHHCINREDVRLSWIMMCCPGRGSYSVQVN---------VQPPTSSAANG---------------------EAPKCTNSSAESSCTNKSASSFKNSSQGCKLTNLQAAAAQYHSNALP------------------VSATPQLDNSLTEHSMDNDIKMHVAPLDVQFRAN--------------MHPSRHHKNRSKGHRASRLTVLREYAYDVPTSVEGSGQSGSPKSRPGSSEGHSRSRR---AYLAYRERQC----NPPQQDSSDAGST----------LPKSGRNVEK---------------------------------------------------------PLSTSSKKDAPRKPAAADLESQQKSYGLNLAVQNGPVKSNGQEGPLLATDITGNIRTG-------------------LWKHETTV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TT36-1", "uniprot_id": "AGRA3_MOUSE", "id": "Q7TT36-1", "name": "Adhesion G protein-coupled receptor A3", "aln": "MEPPPPL-------LLLPLALLALL----WGGERGAAALPAGCKHDGRARGTGRAAAAAEGKVVCSSLELAQVLPPDTLPNRTVTLILSNNKISELKNGSFSG-LSLLERLDLRNNLISRIAPGAFWGLSSLKRLDLTNNRIGCLNADVFRG-LTNLVRLNLSGNLFTSLSQGTFDYLGSLRSLEFQTEYLLCDCNILWMHRWVKERNITVR-DTRCVYPKSLQAQPVTGVKQELLTCDPPLELPSFYMTPSHRQVVFEGDSLPFQCMAS-----------YIDQDMQVLWYQDGRIVETDESQ------------GIFVEKSMIHNCSLIASALTISNIQAGSTGNWGCHVQTKRGNNTRTVDIVVLESSAQYCPPERVVNNKGDFRWPRTLAGITAYLQCTRNTHSSGIYPGSAQDERKAWRRCDRGGFWADDDYSRCQYANDVTRVLYMFNQMPLNLT---NAVATARQLLAYTVEAANFS---DKMDVIFVA-EMIEKFGRFTREEKSKELGDVMVDVASNIMLADERVLWLAQREAKACSRIVQCLQRIATHRLASGAHVYSTYSPNIALEAYVIKAAGFTGMTCSVFQKVAASDRAGLSDYGRRDPDGNLDKQLSFKCNVSSTFSSLALKNTIMEASIQLPSSLLSPKHKREARAADDALYKLQLIAFRNGKLFPATGNSTKLADDGKRRTVVTPVILTKIDGATVDTHHIPVN-------VTLRRIAHGADAVAAQWDFDLLNGQGGWKSDGCCILYSDENITTIQCGSLGNYAVLMD---LTGTELYTPAASLLHP--VVYTTAITLLLCLLAVIISYMYHHSLIRISLKSWHMLVNLCFHILLTCVVFVGGITQTRNASVCQAVGIILHYSTLATVLWVGVTARNIYKQVTKKAKR----CQDPDEPPAPPR---PMLRFYLIGGGIPIIVCGITAAANIKNYGSRPSAPYCWMAWEPSLGAFYGPASFITFVNCMYFLSIFIQLKRHPERKYELKEPTEEQQRLAAN--------------------------------ENGEIN---HQDSMSLSLISTSTLENEHSFQSQLLGASLTLLLYVILWMFGAMAVSLYYPLDLVFSFFFGATCLSFSAFMMVHHCINREDVRLAWIMMCCPGRSSYSVQVN---------VQPPNSSATNG---------------------EAPKCTNSSAESSCTNKSASSFKNSSQGCKLTNLQAAAAQYHSNALP------------------VNATPQLDNSLTEHSMDNDIKMHVAPLDVQFRTN--------------VHPSRHHKNRSKGHRASRLTVLREYAYDVPTSVEGSVQNGLPKSRPGSNEGHSRSRR---AYLAYRERQY----NPPQQDSSDACST----------LPKSSRNVEK---------------------------------------------------------PVSTSSKKDAPRKPAAADLESQQKSYGLNLAVQNGPVKSNGQEGPLLATDVTGNVRTG-------------------LWKHETTV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWK6-1", "uniprot_id": "AGRA3_HUMAN", "id": "Q8IWK6-1", "name": "Adhesion G protein-coupled receptor A3", "aln": "MEPPGRRRGRAQPPLLLPLSLLALLALLGGGGGGGAAALPAGCKHDGRPRGAGRAAGAAEGKVVCSSLELAQVLPPDTLPNRTVTLILSNNKISELKNGSFSG-LSLLERLDLRNNLISSIDPGAFWGLSSLKRLDLTNNRIGCLNADIFRG-LTNLVRLNLSGNLFSSLSQGTFDYLASLRSLEFQTEYLLCDCNILWMHRWVKEKNITVR-DTRCVYPKSLQAQPVTGVKQELLTCDPPLELPSFYMTPSHRQVVFEGDSLPFQCMAS-----------YIDQDMQVLWYQDGRIVETDESQ------------GIFVEKNMIHNCSLIASALTISNIQAGSTGNWGCHVQTKRGNNTRTVDIVVLESSAQYCPPERVVNNKGDFRWPRTLAGITAYLQCTRNTHGSGIYPGNPQDERKAWRRCDRGGFWADDDYSRCQYANDVTRVLYMFNQMPLNLT---NAVATARQLLAYTVEAANFS---DKMDVIFVA-EMIEKFGRFTKEEKSKELGDVMVDIASNIMLADERVLWLAQREAKACSRIVQCLQRIATYRLAGGAHVYSTYSPNIALEAYVIKSTGFTGMTCTVFQKVAASDRTGLSDYGRRDPEGNLDKQLSFKCNVSNTFSSLALKNTIVEASIQLPPSLFSPKQKRELRPTDDSLYKLQLIAFRNGKLFPATGNSTNLADDGKRRTVVTPVILTKIDGVNVDTHHIPVN-------VTLRRIAHGADAVAARWDFDLLNGQGGWKSDGCHILYSDENITTIQCYSLSNYAVLMD---LTGSELYTQAASLLHP--VVYTTAIILLLCLLAVIVSYIYHHSLIRISLKSWHMLVNLCFHIFLTCVVFVGGITQTRNASICQAVGIILHYSTLATVLWVGVTARNIYKQVTKKAKR----CQDPDEPPPPPR---PMLRFYLIGGGIPIIVCGITAAANIKNYGSRPNAPYCWMAWEPSLGAFYGPASFITFVNCMYFLSIFIQLKRHPERKYELKEPTEEQQRLAAN--------------------------------ENGEIN---HQDSMSLSLISTSALENEHTFHSQLLGASLTLLLYVALWMFGALAVSLYYPLDLVFSFVFGATSLSFSAFFVVHHCVNREDVRLAWIMTCCPGRSSYSVQVN---------VQPPNSNGTNG---------------------EAPKCPNSSAESSCTNKSASSFKNSSQGCKLTNLQAAAAQCHANSLP------------------LNSTPQLDNSLTEHSMDNDIKMHVAPLEVQFRTN--------------VHSSRHHKNRSKGHRASRLTVLREYAYDVPTSVEGSVQNGLPKSRLGNNEGHSRSRR---AYLAYRERQY----NPPQQDSSDACST----------LPKSSRNFEK---------------------------------------------------------PVSTTSKKDALRKPAVVELENQQKSYGLNLAIQNGPIKSNGQEGPLLGTDSTGNVRTG-------------------LWKHETTV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "S4X0Q8-1", "uniprot_id": "AGRA3_DANRE", "id": "S4X0Q8-1", "name": "Adhesion G protein-coupled receptor A3", "aln": "-------------MSVLCVLLLAFVLPLRGSSSAGSTECKTYDERSRSAGKSSPSGATLDRKVVCSNMEFRQVPSPDTFPNRTVSLILSNNKIQELLNGSFVG-LSSLERLDIKNNIITHIEPGAFYGLFSLKRLDLSKNLIGCLHVDVFKG-LTNLVKLNLSENKFSSLSQGIFDSLGSLKILEFDSPYLLCDCNLQWLVVWIKEKAIGVK-ETRCSFPRSLQGQLITTLRAETLTCDAPLELPSFQMTPSQHQIVFQGDSLPFQCMAS-----------FVDEDMQVLWYQDGKMVEPDATQ------------GIYIEKSMVQNCSLIASALTISNIQPGFTGNWECRVRTSRGNNTRTVHIVVLESSAKYCLPDRVSNNKGEYRWPRTLAGITAYLPCKRQVTGAGIYSGSSAEDRRAWRRCDRGGQWAEDDYSRCEYMKDVTRVLYIINQMPLNLT---NVVQTAQQLLAYTAEAPNFS---DKVDVIFVA-EMIEKIGKFA--EKYKELGDVMVDISSNLLLADERVLWMAQREARACSRMVESLQRIALLRVSNGALAYSTNSPNIALEAHAIKASSFNGMTCTLFQKLSP-ERTVMAHHGEISPE----RQLSFKCNVTSNLSALALKNTIVEASLQLPPTLFSSLGSS--GQAEEAVYKLHLLAFRNGKLFPPTGNSSILSDGSKRRSVVTPVMITKIEGFPLRDLLSPVN-------VTLRRFLQGSDAVPAFWNFSLQGGQGGWQSDGCRILHQDDNFTTVSCHSLNSYAVLMD---LNRTGYNVFIFRPLHP--VIYSTALVLVLCLLSVIVSYIYHHKSVRISKKCWHMLVNLCLHILLTCAVFVGGINQTYNASVCQAMGIVLHYSTLATALWSGVTARNIYKQVTRKAKR----YEELDEPPPPPR---PMLRFYLIGGGIPIIVCGITAAANIKNYGSQVNAPYCWMAWEPSLGAFYGPAAFIVFVDCMYFLSILIQLRRHPERRFELKEQSEEQQHLSVT--------------------------------EATEITPVHLESSPTAQPVPMSALENEHTFVSQLMGVAGSLTLYAALWVFGALAISQEHPADLVFACLFGALALGLGAFLVAHHCVNRQDMRRHWSQACCLIRRNYAVQVDSLLLPIAGSSGSVMTSRGNG---------------------EATKCPASSAESSCTNKSAPSLRNSTQGCKLTNLQVEAAQCKVVAPST-----------------ANGTAVLDNSLTEHSVDNEIKMHVAPIEIQYRPSSVNNNNLPGNANITGHPGRHHKNRSRAHRASRLTVLREYSYDVPTSVEGSVQS-VPNKRHHHESLHARNSRRA-AYLAYRERQQ----SQLQQDSSDAASTS---------VPRRSRHFSKGTRIGNGF-----------------------------------GHGISNGGLLDGSEADVTNQTKECPKQTLTVELEVQPKSYGLNLACQNGSAKDSER----LNVESSGNVKTG-------------------LWKHETTV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KV24-1", "uniprot_id": "Q7KV24_DROME", "id": "Q7KV24-1", "name": "", "aln": "----------------MPTATATST------AAEGGQAVQVQTHQDTELP-QNPETGIATGQGTASSCPRKCSCRSTAENIHSLKIRCDEQQITNWRELDFGEDVTSIVSINASKNSIALITAEDFRNFTELKRLDLSFNLLTELDKDTFGDSLAHLEKLKLAGNAISHIYEGTFDQMPKLKLLDLSGNPLACDCGLIWLIAWSSSREVRLQPPPKCESPGNFRGMPLKKLRVGKDFHCETLLQPLLELIPSQNQVAFEGDELQLKCHAPRVAIGVPRESEDLPTKAYVFWGWSEKIRAKNSTEDIIYQDPTKVFGDVNLETRHSTDSGILQSILRIASLTQNHTGMWDCTLRSQQANLSQAIVLHVVAKGTLYCEARVVHTNKGTYHWPRTMRGETVLQECVEE-------PSDATQARRASHECGPSGEWLNLDTESCVYVSETTRILEQFAKVNLTLTKGQNALEIARRLHNFTQAQTQLNRIRDPMDLEYIARTLVKYLDQLEQPQQQQEISHLLMDIVSQLLNLPAHLFRAAQSEQGTGQRLLHVVESSAMRLALASTQAEPLPAEMIPWRGSLAQQR---NLFVEFFNISLDAFVSLSCVWLEQSPR-------GFQCNSANDTIPMYEHG-DIDAAIQLPYSVIGNSSTTLPATTTIRSLRLMISLHRNGKLLPNLRGSHNESLSSAIIGILAYSSDGEALQFRADNELDPEEDVYQQRVTVMLRAHPYHNPLSAPQPAWWDADEQRWETSVCQQHYQHRTLVMFSCSRTGYYGLLQRSQYLNDFRSEESGARFRHPPAAVYAGCGLLFACCAFNAVTFAVFGRAVRINRVQRHALVNTWLALGALALAFSLGIYQTASQPQCRLLGLLMHYLGLCVLLWVCVSLSSMYKRLTKTTTSGQGQCPGQDMEPQRERERKPILGIYLVGWGIALLICGISSAVNLAEYAT---YDYCFLHSSTTLNALLVPAVILVIFCGILALCIYYQLSQQAVNVLQLQMQHQQNRQYSDNNTQATEHIDLDWLDANGSATTAAIGGGSGNHGGRKEQDHMQEQYSTLSNPLSSIVDDFERSNLSHLRGHFIFLVLYAGAWLSAAAYVNGGQ---ELYVLSFAGCCSVLGIFLLIFYNLSRNDARQAWSQGRD-GRSIPAKLVTYNNGSQARGAHPSSMMPGPGTAMISNSIVAYKANPGPGSLYEANNSAGSRSNSQCSRSMRSQTRSQTRSQQEQLLQANGAGGVTIINNTSGQPGAGGGPAAGGVSGSTGGAPVPPHSLNALLHGSSHDLIPSAEIFYNPNQINVARKFFKKQKRLAKRNNFELQRQTMPQMQLQMQMQMQLHSQHSLSDASSEQLYSRHHNAMTMLAGGSKINNTNLHYKNQGSPMAGAPKEHGNMGAMSSGGDSMQFKRFVPASASSASKIMQANIYTNIPETLTPQHEVIKLRANGRTRTPSLLDETLHELDDDEEDEEEEEHGQTPATMEEPEHELEEEDASSLDEHAPLYANTLPPASGMSSLFRNRGSSHQPMSSTPVKQPSLEAMNSLGLPEVSLEEPLLQKHEIYVSNSLQVTTSNSIQLDDDFPSVLIRFSQQQQSKSLNNISEMLAGGGGGGGNAPGLDSLGDQQESSQLSVNEGSTLEEQQLRQIYSCSSSNLSQLKGHHPTATVDTEDDGRLLSGSPTNESDLNYQNSEISIRSHGLYAPQADNDLNLTLTDDFRCYQSSNASDADVDVLNEFDDEFVAATGGERVVGDAEQDPHHDHDQDTSIDELYEAIKCRSPLRNKQEAVERFERERERDREKEMEMEAKPLSNSHNENLNETIEDDSSQSSVISYIDPRAANEPRPFPS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . *. . .:. . . : ..*. . : :::.: .:::* : : .* :: : :: :* *: * . * .: .******: * : *. * * . *::* :*:*: * :: : :* ** : .*: *::. * ***.: *: * ..: : :: .:* * .::. :. :: .* * : : **:.*:.*:**.* ::* *. : . *:* . :: : :: .: :*. :..:: * * *:.: . ** * * :::.:.* :::: : *: ..: ** . * .*** ::****: * *. * .: .... : *:* :.*. .* * : * . * * .:.**:* : :: *.** *.: *::* :* .::. * :*: ::* ::: :.:: :: :*:..:::*: *::: ::: ** * : .*::. :: * .: . . : *. .. : .: .*: : . . .* .*:** :. .: :. ::*::*** :::. . : :* : .*****:* .* : .. ::: : * : ..: * :.:.* .: *::. * :.. .:. ..* . *.:* *. ** .:*: . *. * ::: . :**. * *** : : . .* ** ** . . *: :*:::** *.. ** *: .:**::*:.:. * * * *:* :**:* **.:::***::*.*: :*.: **:: ..:*.*: ** ::.:. : *.* ** ::. . :*: ::::: : . * : * . :. . : *:: *:* * * ** *: .* :. :: *.. . :. *:: .: :.*:* * * * : * . * ** :.. * ::*.*:.. .. :..::. : **. .* .. . : : :... : :.. :: :... .:.: : : :* : : . *:..: .. . : : . : : * *::: ::.. .* *: :* . .* . . :. .: . .*: : *. .*. .* . . : :: * *** * ", "identical_positions": 227, "similar_positions": 464, "identity": "12.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-131009-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYK3-1", "uniprot_id": "NRBF2_RAT", "id": "Q9QYK3-1", "name": "Nuclear receptor-binding factor 2", "aln": "------------------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKATAYLSEAMK---LTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQSTDRDGVPHLQASHRPS-EDSEGQSPLLSQTYIPSTEKRLPEEQGVFDRDPDTLLFLLQQKNEPSEPCIGSKAPKDDKTIIEEQATKIAELKRHVEFLVAENERLRKENKQLKAEKARLLKGPAEKELDVDADFVEKSELWGLPPHSDTATASSTWQKFAANTGKAKDIPIPNLPPLDFPSPELPLMELSEDILKGFMND-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6GHP4-1", "uniprot_id": "A0A8I6GHP4_RAT", "id": "A0A8I6GHP4-1", "name": "Nuclear receptor-binding factor 2", "aln": "------------------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKATAYLSEAMK---LTQSEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQRTDRDGVPHLQASHRPS-EDSEGQSPLLSQTYIPSTEKHLPEVQGVFDRDPDTLLFLLQQKNEPSEPCIGSKAPKDDKTIIEEQATKIAELKRHVEFLVAENERLRKENKQLKAEKARLLKGPAEKELDVDADFVEKSELWGLPPHSDTATASSTWQKFAANTGKAKDIPIPNLPPLDFPSPELPLMELSEDILKGFMND-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCQ3-1", "uniprot_id": "NRBF2_MOUSE", "id": "Q8VCQ3-1", "name": "Nuclear receptor-binding factor 2", "aln": "------------------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHRKATTYLSEAMK---LTESEQAHLSLELQRDSHMKQLLLIQERWKRAKREERLKAQQSTERDGAPHLQAPPRPS-EDAEGQSPLLSQPYIPSTERRLPEVQGVFDRDPDTLLFLLQQKNEPSEPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGTAEKELDVDADFVEKSELWGLPSHSESAAASSTWQKFAANTGKAKDIPIPNLPPLDFPSPELPLMELSEDILKGFMND-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96F24-1", "uniprot_id": "NRBF2_HUMAN", "id": "Q96F24-1", "name": "Nuclear receptor-binding factor 2", "aln": "------------------------MEVMEGPLNLAHQQSRRADRLLAAGKYEEAISCHKKAAAYLSEAMK---LTQSEQAHLSLELQRDSHMKQLLLIQERWKRAQREERLKAQQNTDKDAAAHLQTSHKPSAEDAEGQSP-LSQKYSPSTEKCLPEIQGIFDRDPDTLLYLLQQKSEPAEPCIGSKAPKDDKTIIEEQATKIADLKRHVEFLVAENERLRKENKQLKAEKARLLKGPIEKELDVDADFVETSELWSLPPHAETATASSTWQKFAANTGKAKDIPIPNLPPLDFPSPELPLMELSEDILKGFMNN-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13AB16-1", "uniprot_id": "A0AB13AB16_DANRE", "id": "A0AB13AB16-1", "name": "", "aln": "MVNLLSVNKEVATVKTAKPHAQIEMEVIDSPLNRAHHYGRRADQLVMKGKYEEAIECHQEAAELLKEASS---MTQSQQVRLSLELQRDRHLQQQRLIQMSCRQTQLKG-------------------------------------------------------------ELLVSSARPSSSVLGCKTAKDDKTRLEEQSTAIADLWRLVLVLLMDNKRLLEENKRLNAENVGLTMR------------------------------RDPYEEMQSPSASQTQPVFLSLRLLEESPDLQQLMDTAEHS--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JHX0-1", "uniprot_id": "E1JHX0_DROME", "id": "E1JHX0-1", "name": "Nuclear receptor-binding factor 2 MIT domain-containing protein", "aln": "--------------------------MDCAPLNLAHFHERRSERFIRNHRYEEAIKALETSLIYMQDAQKRVALPKSKEVLDTLTLDFQRKLRQIEMRKTQHGLNKLKDYAPLKETS------------------------------------------------PMLPLRPEAGASGGAGGSAQSVAKAIDKTVQDFDAKFTSSLVAKASSTLAHSEPHMETLKKSDSAQE-----------------------------------EQEHDTCDQRLAGSGDLDLPSLAPLELPSFDYSLFTSSSAPSLASYAGMAESFQK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .*** ** **::::: :*****.. . : :.:* . :.:*::. :* *: : :::* : : : : : . : *** : ::. :.* . : ..: : *: .: : . : . : : .* *: .. *: :. ", "identical_positions": 25, "similar_positions": 63, "identity": "7.76%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-131010-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADT3-1", "uniprot_id": "D4ADT3_RAT", "id": "D4ADT3-1", "name": "Wings apart-like protein homolog", "aln": "-----------------------------------------------------------------------------------------------------------------------------MTSRFGKTYSRKG--------------------GNGSSKFDEVFSNKRTTLSTKWGETTFMAKLGQ----------------------------KRPNFKPDIQEIPKKPKVEEEDTG-DPFGFDSDDESLPVSSKSLAQGKG------------------SSYSESSEAVQLEEVTSVLEANSKCSHAVGEDSFASDRCLLVEDSLIGKEKNTNRIPEDNANKSSCTKLITSDKVENFSEEHEKNSHHFHKNAEDSTKKPNAETVAASECKADETKTS-DTWNSQSAKRTESPSESCPVKGSVRTGLYEWDNDFEDIRSEDCILSLDNDSLLEMKDEDLKNRIGGLENLNEAFEEDIIQSVLRPSNCRTYCRANKAKSSQGTSNFDKLMDGTSQTLAKANSESSK-------------DGLNQAKKGSVSCGTSFRGTVGRTRDYTVLHPSCLSVCNVTIQDTMERSMDEFTASTPADLGEAGR------LRKKADIATSKTTTRFRPSNTKSKKDVKLEFFGFEDHD--ETGGDEGGSGSSNYKIKYFG--------FDDLSESEDDDDDDC------------------------QVERKKDKKRTKTAPSPSQQPPPESSDNSQDSQSSTNNAENLDFTEDLPGVP-------------------------------ESVKKPISKQGD--KSKENTRKIFSGPKRSPTKAVYNARHWNH-----------PDSEELPGPP-------------------IVKP-QSVTVRLSSKEPN-QKDDGVFKAPAP-----PLKVIKTVTIPTQPYQEIVT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALKCRKEDKELYTVVQHVKHFNDVVEFGENQEFTDDIEYLLSGLKSTQPLNTRCLSVISLATKCAMPSFRMHLRAHGMVAMVFKTLDDSQHHQNLSLCTAALMYILSRDRLNMDLDRASLDLMIRLLELE--QDASSAKLLNEKDMNKIKEKIRRLCETVHN----KHLDLENITTGHLAMETLLSLTSKRAGDWFKEELRLLGGLDHIVDKVKECVD---HLSRD-EDEEKLVASLWGAERCLRVLESVTVHNPENQSYLIAYKDSQLIISSAKALQHCEDLIQQYNRAENSICIADSKPLPYQNVTNHVGKAVEDCMRAIIGVLLNLTNDN-----EWGSTKTGEQEGLIGTAMNCVLQVPKYLPQEQRFDIRVLGLGLLINLVEYSARNRHCLVNMETSCS----------FDSSFSSGEG--------DHNLRLAGQVHAVQALVQLFLE-----RERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEKTDGAEEKQKKEDEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQES-------------------PINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQKSISRVIEYLEHC-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q65Z40-1", "uniprot_id": "WAPL_MOUSE", "id": "Q65Z40-1", "name": "Wings apart-like protein homolog", "aln": "-----------------------------------------------------------------------------------------------------------------------------MTSRFGKTYSRKG--------------------GNGSSKFDEVFSNKRTTLSTKWGETTFMAKLGQ----------------------------KRPNFKPDIQEIPKKPKVEEEDTG-DPFGFDSDDESLPVSSKNLAQGKG------------------SSYSESSEAAQLEEVTSVFEANSKCSHVVGEDSFASDRCLLVEDTLIGKEKSISRIPEDNANKSSCTKLLTSDKVENFSEEHEKNSHHFHKNAEDSTKKPNAETAVASEYKADETKETNDTWNSQSGKRTESPSESCPVKGSVRTGLYEWDNDFEDIRSEDCILSLDNESLLEMKDEDLKNRIGGLENLNETFEEDIIQSVLRPSNCRTYCRANKARSSQGASNFDKLMDGTSQSLAKANSESSK-------------DGLNQAKKGSASCGTSFRGTVGRTRDYTVLHPSCLSVCNVTIQDTMERSMDEFTASTPADLGEAGR------LRKKADIATSKTTTRFRPSNTKSKKDVKLEFFGFEDHD--ETGGDEGGSGSSNYKIKYFG--------FDDLSESEDDDDDDC------------------------QVERKKDKKRTKTAPSPSQQPPPESSDNSQDSQSSTNNAENLDFTEDLPGVP-------------------------------ESVKKPISKQGD--KSKENTRKIFSGPKRSPTKAVYNARHWNH-----------PDSEELPGPP-------------------IAKP-QRVTVRLSSKEPN-QKDDGVFKAPAP-----PLKVIKTVTIPTQPYQEIVT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALKCRKEDKELYTVVQHVKHFNDVVEFGENQEFTDDIEYLLSGLKSTQPLNTRCLSVISLATKCAMPSFRMHLRAHGMVAMVFKTLDDSQHHQNLSLCTAALMYILSRDRLNMDLDRASLDLMIRLLELE--QDASSAKLLNEKDMNKIKEKIRRLCETVHN----KHLDLENITTGHLAMETLLSLTSKRAGDWFKEELRLLGGLDHIVDKVKECVD---HLSRDDEDEEKLVASLWGAERCLRVLESVTVHNPENQSYLIAYKDSQLIISSAKALQHCEDLIQQYNRAENSICVADSNPLPYQNVTNHVGKAVEDCMRAIIGVLLNLTNDN-----EWGSTKTGEQEGLIGTAMNCVLQVPKYLPQEQRFDIRVLGLGLLINLVEYSARNRHCLVNMQTSCS----------FDSSFSSGEG--------DHSLRLAGQVHAVQALVQLFLE-----RERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEKTDGAEEKQKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQES-------------------PINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQKSISRVIEYLEHC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z5K2-1", "uniprot_id": "WAPL_HUMAN", "id": "Q7Z5K2-1", "name": "Wings apart-like protein homolog", "aln": "-----------------------------------------------------------------------------------------------------------------------------MTSRFGKTYSRKG--------------------GNGSSKFDEVFSNKRTTLSTKWGETTFMAKLGQ----------------------------KRPNFKPDIQEIPKKPKVEEESTG-DPFGFDSDDESLPVSSKNLAQVKC------------------SSYSESSEAAQLEEVTSVLEANSKISHVVVEDTVVSDKCFPLEDTLLGKEKSTNRIVEDDASISSCNKLITSDKVENFHEEHEKNSHHIHKNADDSTKKPNAETTVASEIKETN-----DTWNSQFGKRPESPSEISPIKGSVRTGLFEWDNDFEDIRSEDCILSLDSDPLLEMKDDDFKNR---LENLNEAIEEDIVQSVLRPTNCRTYCRANKTKSSQGASNFDKLMDGTSQALAKANSESSK-------------DGLNQAKKGGVSCGTSFRGTVGRTRDYTVLHPSCLSVCNVTIQDTMERSMDEFTASTPADLGEAGR------LRKKADIATSKTTTRFRPSNTKSKKDVKLEFFGFEDH---ETGGDEGGSGSSNYKIKYFG--------FDDLSESEDDEDDDC------------------------QVERKTSKKRTKTAPSPSLQPPPESNDNSQDSQSGTNNAENLDFTEDLPGVP-------------------------------ESVKKPINKQGD--KSKENTRKIFSGPKRSPTKAVYNARHWNH-----------PDSEELPGPP-------------------VVKP-QSVTVRLSSKEPN-QKDDGVFKAPAP-----PSKVIKTVTIPTQPYQDIVT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALKCRREDKELYTVVQHVKHFNDVVEFGENQEFTDDIEYLLSGLKSTQPLNTRCLSVISLATKCAMPSFRMHLRAHGMVAMVFKTLDDSQHHQNLSLCTAALMYILSRDRLNMDLDRASLDLMIRLLELE--QDASSAKLLNEKDMNKIKEKIRRLCETVHN----KHLDLENITTGHLAMETLLSLTSKRAGDWFKEELRLLGGLDHIVDKVKECVD---HLSRD-EDEEKLVASLWGAERCLRVLESVTVHNPENQSYLIAYKDSQLIVSSAKALQHCEELIQQYNRAEDSICLADSKPLPHQNVTNHVGKAVEDCMRAIIGVLLNLTNDN-----EWGSTKTGEQDGLIGTALNCVLQVPKYLPQEQRFDIRVLGLGLLINLVEYSARNRHCLVNMETSCS----------FDSSICSGEG--------DDSLRIGGQVHAVQALVQLFLE-----RERAAQLAESKTDELIKDAPTTQHDKSGEWQETSGEIQWVSTEKTDGTEEKHKKEEEDEELDLNKALQHAGKHMEDCIVASYTALLLGCLCQES-------------------PINVTTVREYLPEGDFSIMTEMLKKFLSFMNLTCAVGTTGQKSISRVIEYLEHC-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TDM0-1", "uniprot_id": "A0A8N7TDM0_DANRE", "id": "A0A8N7TDM0-1", "name": "Wings apart-like protein homolog", "aln": "-----------------------------------------------------------------------------------------------------------------------------MTSRFSKTYTRKG--------------------GEASSKFDEVFSNKKATLTTKWGESTYKAHLGI----------------------------KRPSFKPDVSELTKRPRFDDDDSSEDPFGFDSDDESKTVTSRDTAQSEM------------------DSDTAGPKNEQLKTQT---EKPSRGTLVTSTSSLGSS-----------TNISRGAVGVNSPAKTSPASSYVTGTVGTWSKSNVTVSKQLSQ--VSSLKTPSRGIS--------------NDWDSFGEDSPPGAGEGSSTQTSNSS---------DELKSAEQCPAEPEPPVEQPVD---------FEQL----------PLLKPSSDRVYRRP-RGKETESSAAGDTIP-AVSSVSAPAPVMSSN-------------AGVAGSSGVKPPAGR------GRVRDYTVLHPSCVSVCNVTIQDSIERSVDDFVMPVQADIGEAGT------FRRKADTQAPKP-TRFRPTQSKSKKETKLEFFGFEENEAQDADGDATGSGSTSYKIKYFG--------FDDLSESDSEDDDDS------------------------AARERKKNKKAEAEALSTGTGSPQFSDSQESQQSQSSLSTDSQESLDETGAT-------------------------------GSQKERHRKQSN--KSKEIGRKIFSGPKKSPAKAVYNARHWNQ-----------PESEEVPTPASHT--------------VAVPKPSASSSSTSSSKDTNSHKDDGVFKAPPP-----PPKVIKSVTIPTELNQDIVT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALKCRKEHKELYTVVQHVKHFNDVVEFGENQEFTDDFEYLETGLKSTQPLNTRCLSIISLATRCAMPSFRMHLRARGKVAQVFKMLSDAQQHPNMALCTASLMYILSRDRLNMDLDRSCLELMIRLLEME--QDDSVADQLTAKEMSKVKEKIRKLCETVHN----KHLDLENITTGHLAMETLLSLTSKRAGDWFKEELRLLGGLDHIVDKVKECVE---NLNKE-EDKESLVASLWGAERCLRVLESVTVHNPENQAYLIAYKDSQLIMSSARALQHCEQMIQRYSREVSS---SSSSTLP-QSSHSNVGKAVEDCMRAVIGVLLNLTHDN-----EWGSTKTGEQDGLILTALDCVLKVPRYLPQEQRFDIRVLGLGLLINLVEYSARNRECLVEMEVDMSYLMEAEAVVKMENDVKTEEQKRDQMEEEEKRKATLKSLNALAALVQLFLE-----RERAAVLAEAQTDDLISEAPKSQADQSGEWQETSGEIQWVASETNDTND---KKEEEEEELDLNKALQHAGKHMEDSIVASYSALLLGCLCQGS-------------------PMNVKTVRENLPKGDFSIMTEMLKKFLNFMNLTCSVGTTGQKSISRVIDYLEHC-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W517-1", "uniprot_id": "WAPL_DROME", "id": "Q9W517-1", "name": "Protein wings apart-like", "aln": "MSRWGKNIVVPLDSLCKEKENTNRPTVARSVGTVGKWGKMGFTSTRTYTLPAIHPMAAAAAAAAAAASPSQSPASTQDHDPNDLSVSVPEPPKPKKFFKSRNTAPPEVIAQIIQQLPHCGAGASPMRDHFSSAGAGAGGLTPTSGAQEAGGVKLKPGKGASSAERKRKSPKKKAATTSASTPSTPGAFYGASDRDGDGLSDPASEQPEQPSSASGKQKQKKPKEEKKLKPEAPPSRVLGRARKAVNYREVDEDERYPTPTKDLIIPKAGRQPAEVAATATLAAASSEAFISSTFGSPGSEPSLPPPTSAPSASASTSSQLPSASGSASNPPSASRTPEHPPIVLRISKGTSRLVSTDSEEPPSSSPAHQNQLNQLSVTEEEPAERSGDETVPASTPKITVKPLRPPTAADSVDGSSAAVGGASAGDSFEERKSQSLEPNEDEEEEEEEEDEEEEPPEINYCTVKISPDKPPKERLKLIIKTDVIRNAIAKAAAAAESRSEKKSRSKKHKHKQLLAAGSGAAPASGATPAEINSEFKTPSPHLALSEANSQQAQHTPSHLHQLHQLHPQRGSAVISPTTRSDHDFDSQSSVLGSISSKGNSTPQLLAQAVQEDSCVIRSRGSSVITSDLETSQHSSLVAPPSDIESRLESMMMTIDGAGTGAASAVPETPLQEDILAVLRGEVPRLNGNTDPEPTEEEDQQQQPKRATRGRGRKANNNVDVTPPATETRTRGRAKGADATTAAISPPTGKRNTRGTRGSRKAEQEVDMEVDETAMTTVPANEEQLEQATLPPRRGRNAAARANNNNLASVNNNINKIAANLSAKAEASRLAEGGVAGGAARSYGRKRKNQQVTQVLQQEPVPEEQETPDAEEEQPTPAKIPHTDHREHSPDHDPDPDPDELSNNSNNSSLQHDGSSSSPPPRDFKFKDKFKRTLTLDTQGAANAGAGGAAAAAPPESSGEQRGAVKLVISKKKGSIFKSRALVPSDQAEQATVAKRHLYKHSWDAALEANGGGTNSDASNASASGVGVAGAKDHLHHLAAGKSDGDFGDSPSSNNNGSSSACSSASTLRGDSPALGKISRLAGKQGVPATSTSSDAFDLDLEPIAGELDLERSAAGASAGGTGATTGGGGATGGGGPVRVDRKTKDYYPVVRNVKTAHQIQEIGEYQEMDDDVEYILDALQPHNPPATRCLSALQLAAKCMMPAFRMHVRAHGVVTKFFKALSDANKDLSLGLCTSAIMYILSQEGLNMDLDRDSLELMINLLEADGVGGSTETGHPDRAGYDRNKQKVRELCEEIKAQGKGTHLNVDSLTVGTLAMETLLSLTSKRAGEWFKEDLRKLGGLEHIIKTISDFCRPVIACDTEIDWQPTLLDNMQTVARCLRVLENVTQHNETNQRYMLTSGQGKAVETLCQLYRLCSRQIMLHPSDGGG------------SNKEHPGVAMRELLVPVLKVLINLTHTFNEAQPSLGAELLGQRGDVVETSFRLLLLSANYIPDQCVFELSILVLTLLINLCMHTVPNRAALMQAAAPAEY---------VADNPPAQGSVSALQALLEYFYKCEELARLVEKNTDAFLESNEKGKKKQEEVEETVNNLVQRAGHHMEHTLKGSYAAILVGNLIADNELYESVVRRQLRGNSFKEIIGVLEKYHTFMNLTSSLEAAFVAHMKSTKRIIDNFKKRDYIYEHSDEHDNPLPLNLETTAQVLAVGADASHAATSSTTVGSGSAPSSTSATGTTRAPRVYKTYSSHR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .:*..: : * * .*:: .. .:*::: :: :* * * *:*. : .:. . .:. : .:** ...::. : .: .. . : : : . . . * . : . :* : . : . ::: .. : .. . . . . .. . :: .. : . . : *.* : : . *. : :: : : . . * . :. . .. *. :*: *: * :. *.:: *:.. .. :.:* : :. :.. * :.: . .: : .: .: * . .: : . :. ::. ::.: :::* .. :. : : . .: .* . . .. :. . : : * .. . * :: * . .:* :: .* . : *. :: *: *:.:* * . .* ...: . :.** .:*.* *. :::*: *: : : .:: :: *: *.**::** ::: *:** **: **.**: .*:. :* ***** :.**::* **:****:**:* *: .** *.*:::. .:.***:::*****:: ******* .*:***.*** : . : : .: *:*:*.*** :: .**:::.:*.* ***************:****:** ****:**:..:.: . : : : .*: .: . *******.** ** ** *::: :.: : : .: : *. * : .. . .: * *:.: : .:: **:***: . *: *:: .:: *:: :* ..*:*:: *:: :* * ***** ::. ** .*:: . . . .. : : . : .: *** ::: : *: .: : . : .*.: . .* : : :. :*: *: :: ..: *:: * : . . *:*: *. : *. * : : .. :. . ..:..:** . .** . . ", "identical_positions": 206, "similar_positions": 407, "identity": "11.69%" } ]