[ { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100217-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJ79-1", "uniprot_id": "DYHC2_RAT", "id": "Q9JJ79-1", "name": "Cytoplasmic dynein 2 heavy chain 1", "aln": "MAGSLSDVRKLFLFTTTQNYFGLRPELWDQTPLSNCPEVNNFLDDGNQMLLRVQRSDAGLAFSNTIDFDDTKDKVLVFFKLRPEVIT--DGNLHTNILVSSMLESPINSLYQAVRQVFAPMLLKDQEWSRNFDPKLQNLLSELEAGLGVVLRKSDTN-LPKLKLKEDDTRGILTPSDEFQFWIEQA-HRGSKQISKERASYFKELFETIAREFYNLDSLS-LLEVVDLVETTRDVVDDVWRQAEHDHYPESRMLHLLDVIGGSFGRFVQKKLGSLKLWEDPYYLVKENLKAGISICEQWVIVCSHLTGQVWQRYVPHPWKSEKYFPETLDRLGKRLEEVLAIRTIHEKLLYFLPASEERIVCLSRVFEPFTGVNPVQYNPYTEPLWKAAVSQYEKIIAPAEQKIAGKLKNYISEIQDSPQQLLQAFLKYKELVKRPTISKELMLERETLLARLGDSAKDFRLDFENRCRGIPGDASGPLSGKNLSEVVNNIVWVRQLELKVDDTIKIAEALLSDLSGFRSFHRSAEDLLDQFKLYEQEQFDDWSREVQSGLSDSRSGLCIEANSRIMELDPNDGALKVHYSDRLVILLREVRQLSALGFVIPAKIQQVANVAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIK-NSKAGS---GGKSQITWDNPKELEGYIQKLQNAAERLATENRRLRKWHITFCEKVVILMNIDLLRQQQRWKDGLQELRTGLASVAAQGFQPSDMRAWRQHWNHQLYKALEHQYQMGLEALNENLPEINVDLTYKQGRLQFRPPFEEIRAKYYREMKRFIGIPNQFKGVGGAGDESIFSVMIDRNASGFLTIYSKAEDLFRRLSAVLHQHKEWVVIGQVDMEALVEKNLSTVHDWEKNFKALKIKGKEVERLPSAVK-VDCLNINCSPVKTVIDDLIQKLFDLLVLSLKKSIQTHIHEIDTFVTEAMKVLTVIPQSVEEIGDTNLQYSNLQDRRPEILPLFQEAEDKNRLLRTVAGGGVETVSNLRAKWDKFELMMESHQLMIKDQIEVMKGNVKSRLQIYYQELDKFKARWDQLKPGDDIIETGQQNTMDQSAKSIKEKKIEFDDLEVIRKKLVDDCHHFGLEESNFSLA--YSISKDIESCAQIWALYEEFQQGLQEMAKEDWITYRTKIYIFEEFLINWHERLRKVEEHSVMTVKLQSEVDRYKIIIPILKYVRGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVEKASDLKDLNSRAQGEVTIREALRELDLWGVGAVFSLIDYEDSQNRTIKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAQLDEYLQNLNHIQRKWVYLEPIFGRGALPKEQTRFNKVDEDFRSIMMDIRKDSRVTTLTTHAGIRNTLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTN-PSVIQSHLKKLFAGINSVCFDEESK-----------HITAMRSLEGEVVPFKSKVLLSNNVEAWLNDLALEMKQTLKQLLKECVTAGRSSQGAIDP---SLFPSQILCLAEQIKFTEDVEDAIRDHSLHQIEAQLAAKLERYTSVDTSSEDPGNSESGILELKLKTLILDIIHNIDIVKQLNQAQVHTTDDWAWKKQVRFYMK----------SDHTCYVQMVDSELQYTYEYQGNAPKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEEAVLSAVSMQIQTIQDALKNHRSVCELLGKEVEVNANSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILYSEGFKDAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLKKSGTKQDVNE---NHIVVQALRLNTMSKFTFADCTRFDALIKDVFPGIDFKEVEYNELSSALKQVFEEANYEVIPNQMKKALELYEQLRQRTGVVIVGPSGAGKSTLWRMLRAALCKIGKVVKQYTMNPKAMPRHQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWLRNQPVEYRSNLENWIGDYFSKALQWVLKQNDYVVETSLVGTVMNG--LSHLHGCKYHDQFIINLIRGLGGNLNMKSRLEFTKEVFNWARETPPDSHRPMDTYFDCDRGQLASYVLKKPESLTADDFSSGHSLPVIQTPDMQRGLDYFKPWLSSE--TKQPFILVGPEGCGKGMLLRYAFSQLRSTEIATIHCSAQTTSRHLLQKLSQTCMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDENLEWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCAVDYPEREQLQTIYGAYLEAVLHKNLKNHSIWGSSSK-IYLLAGSMVQVYEQVRAKFT--VDDYSHYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEVVAYEARRLFRDKIVGVKELHLFDNILTSVLQGDWGSDILDNMADSFYVTWGAQHISGAKIAPGQPLPPHGKPLGKLSSADLKDVIKKGLIHYGRDNQNLDILLFQEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTVTSLVSHMHGAVLFSPKISRGYEPKQFRTDLKHVLHLAGIEAQQVVLLLEDYQFVHP-TFLEMINSLLSSGEVPGLYTLEELEPLLLPLKDQASQDGFFGPVFNYFTYRIQQNLHIVLIMDSANLNFIINCESNPALHKKCRVLWMEGWSDSSMKKIPEMLFSEADIEEKYE-KKRKDEKKKSSVDPDFIKSFLLIHESCKAYGATPSRYMTFLRVYSAISSSKRKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSILLRIKQDEADSALQEITVSMQDASEQKTELERLKHRIAEEVVKIEERKSKIDDELKEVQPLVNEAKLAVGNIRPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNIPKEIRESVEELLFKNKASFDPKNAKRASTAAAPLAAWVKANVQYSHVLERIQPLETEQSGLELNLKKTEDRKRKLEDLLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLISQLDREHRRWNAQVAEIAEELATLPKRAQLAAAFITYLSAAPEGLRKNCLEEWTKAAGL-EKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQS-------RVCPFLIDPSSQATEWLKTHLKDS--HLEVINQQDSNFITALELAVRFGKTLIIQEMDGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEDFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLARLEESLLETLATSQGNILENKDLIESLNQTKASSALIQDSLKESYKLQISLDRERDAYLPLAESASKMYFIISDLSKINNMYRFSLASFLRLFQRALQNKQDSESTEQRIQCLVNSLKHMVYEYICRCLFKADQLMFALHFVRGMHPEFFQENEWDTFTGVVVGDMLRKADSQQRIRDQLPSWIDQERSWAVATLKISLPGLYQTLCFEDGTLWRTYYHHSMCEQEFPSILAKKVSLFQQVLVVQALRPDRLQSAMALFACKALGLKELSPLPLNLKRLYKETLEIEPILIIISPGADPSQELQELANAERSSERYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNTLQPKESFRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTYESWTPEQISKKDNIHR-AHALFSLAWFHAACQERRNFIPQGWTKFYEFSLSDLRAGYHVIDRLFDGSKD--VQWEFVHGLLENSIYGGRIDNYFDLRVLQSYLKQFFNSSIIDVLNQRNKKSIFPYSISLPDSCSILDYRAVIEKLPEDDKPSFFGLPANIARSSQRMTSSQVISQLR-------------ILGRSVTAGCKFDREIWSNELSPVLNLWKKLNQNSNLIHQKVSPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLTWQSKWEGP--EDPLQYLRGLVARTLAIQNWVEKAEKQALLADTLDLSELFHPDTFLNALRQETARATGCSVDSLKFVASWKG--RLQEAKLQIKISGLLLEGCSFDGSRLS------ENQHDSPSVSSVLPCYMGWTPQGSYGPYSPDECISLPVYTSAERDCVVTNIDVPCG-GNQDQWIQCGAALFLKNQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q45VK7-1", "uniprot_id": "DYHC2_MOUSE", "id": "Q45VK7-1", "name": "Cytoplasmic dynein 2 heavy chain 1", "aln": "MAGSLGDVRKLFLFTTTQNYFGLRPELWDQPPLSNCPEVNNFLDDGNQMLLRVQRSEAGLAFSNTIDFDDAKDKVLVFFKLRPEVIT--DGNLHNNILVSSMLESPINSLYQAVRQVFAPMLLKDQEWSRNFDPKLQNLLSELEAGLGIVLRKSDTN-LPKLKLKEDDTRGILTPSDEFQFWIEQA-HRGSKQISKERASYFKELFETISREFYNLDSLS-LLEVVDLVETTRDVVDDVWRQTEHDHYPESRMLHLLDVIGGSFGRFVQKKLGSLKLWEDPYYLVKENLKAGISICEQWVIVCSHLTGQVWQRYVPHPWKSGKYFPETLDKLGKRLEEVLAIRTIHEKLLYFLPASEERIVCLSRVFEPFTGVNPVQYNPYTEPLWKAAVSQYEKIIAPAEQKIAGKLKNYISEIQDSPQQLLQAFLKYKELVKRPTISKELMLERETLLARLGDSAKDFRLDFENRCRGIPGDPSGPLSGKNLSEVVNNIVWVRQLELKVDDTIKIAEALLSDLSGFRSFHRSAEDLLDQFKLYEQEQFDDWSREVQSGLSDSRSGLCIEANSRIMELDPNDGALKVHYSDRLVILLREVRQLSALGFVIPAKIQQVANVAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIK-NSKAGS---GGKSQITWDNPKELEGYIQKLQNAAERLATENRRLRKWHTTFCEKVVILMNIDLLRQQQRWKDGLQELRTGLATVAAQGFQASDMRAWRQHWNHQLYKALEHQYQVGLEALNENLPEINVDLTYKQGRLQFRPPFEEIRAKYYREMKRFIGIPNQFKGVGEAGDESIFSVMIDRNASGFLTIYSKAEDLFRRLSAVLHQHKEWVVIGQVDMEALVEKNLSTVHDWEKNFKALKIKGKEVERLPSAVK-VDCLNINCSPVKTVIDDLIQKLFDLLVLSLKKSIQTHIHEIDTFVTEAMKVLTVIPQSVEEIGDTNVQYSNLQDRRPEILPLFQEAEDKNRLLRTVAGGGVETVSNLRAKWDKFELMMESHQLMIKDQIEVMKGNVKSRLQIYYQELDKFKARWDQLKPGDDIIETGQQNTMDQSAKSIKEKKIEFDDLEVIRKKLVDDCHHFGLEEPNFSLA--YSISKDIESCAQIWALYEEFQQGLQDMAKEDWITYRAKIYLFEEFLINWHERLRKIEEHSVMTVKLQSEVDRYKMIIPILKYVRGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVEKASELKDLNSRAQGEVTIREALRELDLWGVGAVFSLIDYEDSQNHTIKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAQLDEYLQNLNHIQRKWVYLEPIFGRGALPKEQTRFNKVDEDFRSIMMDIRKDSRVTTLTTHAGIRNTLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTN-PSVIQSHLKKLFAGINSVCFDEESK-----------HITAMKSLEGEVVPFKSKVLLSNNVEAWLNDLALEMKQTLKQLLKECVTAGRSSQGAIDP---SLFPSQILCLAEQIKFTEDVENAIKDHSLHQIEAQLVAKLERYTSVDTSSEDPGNSESGILELKLKALILDIIHNIDIVKQLNQVQVHTTDDWAWKKQVRFYMK----------SDHTCYVQMVDSELQYTYEYQGNAPKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEEAVLSAVSMQIQTIQDALKNHRTVCELLGKEVEINANSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSRPDNDLIAEVILYSEGFKDAKELGRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLKKNSTKQDVNE---NHIVVQALRLNTMSKFTFADCTRFDALIKDVFPGIDFKEVEYDELSSALKQVFEEANYEVIPNQMKKALELYEQLRQRTGVVIVGPSGAGKSTLWRMLRAALCKIGKVVKQYTMNPKAMPRHQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWLRNQPLEYRSNLENWIGDYFSKALQWVLKQNDYVVETSLVGTVMNG--LSHLHGCKYHDQFIINLIRGLGGNLNMKSRLEFTKEVFNWARETPPDSHRPMDTYYDCDRGQLASYMLKKPESLTADDFSNGHILPVIQTPDMQRGLDYFKPWLSSD--TKQPFILVGPEGCGKGMLLRYAFSQLRSTEIATIHCSAQTTSRHLLQKLSQTCMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDENLEWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCAIDYPEREQLQTIYGAYLEAVLHKNLKNHSIWGSSSK-IYLLAGSMVQVYEQVRAKFT--VDEYSHYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGVKELHLFDNILTSVLQGDWGSDILDNMADSFYVTWGAHHVSGGKTAPGQPLPPHGKPLGKLTSADLKDVIKKGLIHYGRDNQNLDILLFQEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTVTSLVSHMHGAVLFSPKISRGYEPKQFRNDLKHVLQLAGIEAQQVVLLLEDYQFVHP-TFLEMINSLLASGEVPGLYTLEELEPLLLPLKDQASQDGFFGPVFNYFTYRIQQNLHIVLIMDSANLNFIVNCESNPALHKKCQVLWMEGWSDSSMKKIPEMLFSETDGEEKYE-KKRKDEKKRNSVDPDFIKSFLLIHESCKAYGATPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSILLRIKQDEADSALQEITVSMQDASEQKTELERLKQRIAEEVVKIEERKSKIDDELKEVQPLVNEAKLAVGNIRPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNIPKEIRESVEELLFKNKASFDPKNAKRASTAAAPLAAWVKANVQYSHVLERIQPLETEQSGLELNLKKTEDRKRKLEDLLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLISQLDREHRRWNAQVAEIAEELATLPKRAQLAAAFITYLSAAPEGLRKNCLEEWTKAAGL-EKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQS-------RVCPFLIDPSSQATEWLKTHLKDS--HLEVINQQDSNFITALELAVRFGKTLIIQEMDGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEDFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLARLEESLLETLATSQGNILENKDLIESLNQTKASSALIQDSLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLASFLRLFQRALQNKQDSENTEERIQCLVNSLKHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQRIRDQLPSWIDQERSWAVATLKISLPSLYQTLCLEDGAFWRTYYHHSMCEQEFPSILAKKVSLFQQVLVVQALRPDRLQSAMALFACKALGLKELSPLPLNLKRLYKETLEIEPILIIISPGADPSQELQELASAERSSECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNTLQPKDSFRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTYESWTPEQISKRDNIHR-AHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYHVIDRLFDGTKD--VQWEFVHGLLENSIYGGRVDNYFDLRVLQSYLKQFFNSSIIDVLNQRNKKSIFPYSISLPNSCSILDYRAVIEKLPEDDKPSFFGLPANIARSSQRMISSQVISQLR-------------ILGRSVTAGCKFDREIWSNELSPVLNLWKKLNQNSNLIHQKVSPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLTWQSRWEGP--EDPLQYLRGLVARTLAIQNWVEKAEKQVLLADTLDLSELFHPDTFLNALRQETARATGCSVDSLKFVASWKG--RLQEAKLQIKISGLLLEGCSFDGNRLS------ENQHDSPSVSSVLPCYMGWTPQGSYGPYSPDECISLPVYTSAERERVVTNIDVPCG-GNQDQWIQCGAALFLKNQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NCM8-1", "uniprot_id": "DYHC2_HUMAN", "id": "Q8NCM8-1", "name": "Cytoplasmic dynein 2 heavy chain 1", "aln": "MANGTADVRKLFIFTTTQNYFGLMSELWDQPLLCNCLEINNFLDDGNQMLLRVQRSDAGISFSNTIEFGDTKDKVLVFFKLRPEVIT--DENLHDNILVSSMLESPISSLYQAVRQVFAPMLLKDQEWSRNFDPKLQNLLSELEAGLGIVLRRSDTN-LTKLKFKEDDTRGILTPSDEFQFWIEQA-HRGNKQISKERANYFKELFETIAREFYNLDSLS-LLEVVDLVETTQDVVDDVWRQTEHDHYPESRMLHLLDIIGGSFGRFVQKKLGTLNLWEDPYYLVKESLKAGISICEQWVIVCNHLTGQVWQRYVPHPWKNEKYFPETLDKLGKRLEEVLAIRTIHEKFLYFLPASEEKIICLTRVFEPFTGLNPVQYNPYTEPLWKAAVSQYEKIIAPAEQKIAGKLKNYISEIQDSPQQLLQAFLKYKELVKRPTISKELMLERETLLARLVDSIKDFRLDFENRCRGIPGDASGPLSGKNLSEVVNSIVWVRQLELKVDDTIKIAEALLSDLPGFRCFHQSAKDLLDQLKLYEQEQFDDWSRDIQSGLSDSRSGLCIEASSRIMELDSNDGLLKVHYSDRLVILLREVRQLSALGFVIPAKIQQVANIAQKFCKQAIILKQVAHFYNSIDQQMIQSQRPMMLQSALAFEQIIK-NSKAGS---GGKSQITWDNPKELEGYIQKLQNAAERLATENRKLRKWHTTFCEKVVVLMNIDLLRQQQRWKDGLQELRTGLATVEAQGFQASDMHAWKQHWNHQLYKALEHQYQMGLEALNENLPEINIDLTYKQGRLQFRPPFEEIRAKYYREMKRFIGIPNQFKGVGEAGDESIFSIMIDRNASGFLTIFSKAEDLFRRLSAVLHQHKEWIVIGQVDMEALVEKHLFTVHDWEKNFKALKIKGKEVERLPSAVK-VDCLNINCNPVKTVIDDLIQKLFDLLVLSLKKSIQAHLHEIDTFVTEAMEVLTIMPQSVEEIGDANLQYSKLQERKPEILPLFQEAEDKNRLLRTVAGGGLETISNLKAKWDKFELMMESHQLMIKDQIEVMKGNVKSRLQIYYQELEKFKARWDQLKPGDDVIETGQHNTLDKSAKLIKEKKIEFDDLEVTRKKLVDDCHHFRLEEPNFSLA--SSISKDIESCAQIWAFYEEFQQGFQEMANEDWITFRTKTYLFEEFLMNWHDRLRKVEEHSVMTVKLQSEVDKYKIVIPILKYVRGEHLSPDHWLDLFRLLGLPRGTSLEKLLFGDLLRVADTIVAKAADLKDLNSRAQGEVTIREALRELDLWGVGAVFTLIDYEDSQSRTMKLIKDWKDIVNQVGDNRCLLQSLKDSPYYKGFEDKVSIWERKLAELDEYLQNLNHIQRKWVYLEPIFGRGALPKEQTRFNRVDEDFRSIMTDIKKDNRVTTLTTHAGIRNSLLTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQSTN-PSVIQSHLKKLFAGINSVCFDEKSK-----------HITAMKSLEGEVVPFKNKVPLSNNVETWLNDLALEMKKTLEQLLKECVTTGRSSQGAVDP---SLFPSQILCLAEQIKFTEDVENAIKDHSLHQIETQLVNKLEQYTNIDTSSEDPGNTESGILELKLKALILDIIHNIDVVKQLNQIQVHTTEDWAWKKQLRFYMK----------SDHTCCVQMVDSEFQYTYEYQGNASKLVYTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLLGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEESVLSAVSMQIQTIQDALKNHRTVCELLGKEVEVNSNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMSHPDNELIAEVILYSEGFKDAKVLSRKLVAIFNLSRELLTPQQHYDWGLRALKTVLRGSGNLLRQLNKSGTTQNANE---SHIVVQALRLNTMSKFTFTDCTRFDALIKDVFPGIELKEVEYDELSAALKQVFEEANYEIIPNQIKKALELYEQLCQRMGVVIVGPSGAGKSTLWRMLRAALCKTGKVVKQYTMNPKAMPRYQLLGHIDMDTREWSDGVLTNSARQVVREPQDVSSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFVFETHDLSCASPATISRMGMIFLSDEETDLNSLIKSWLRNQPAEYRNNLENWIGDYFEKALQWVLKQNDYVVETSLVGTVMNG--LSHLHGCRDHDEFIINLIRGLGGNLNMKSRLEFTKEVFHWARESPPDFHKPMDTYYDSTRGRLATYVLKKPEDLTADDFSNGLTLPVIQTPDMQRGLDYFKPWLSSD--TKQPFILVGPEGCGKGMLLRYAFSQLRSTQIATVHCSAQTTSRHLLQKLSQTCMVISTNTGRVYRPKDCERLVLYLKDINLPKLDKWGTSTLVAFLQQVLTYQGFYDENLEWVGLENIQIVASMSAGGRLGRHKLTTRFTSIVRLCSIDYPEREQLQTIYGAYLEPVLHKNLKNHSIWGSSSK-IYLLAGSMVQVYEQVRAKFT--VDDYSHYFFTPCILTQWVLGLFRYDLEGGSSNHPLDYVLEIVAYEARRLFRDKIVGAKELHLFDIILTSVFQGDWGSDILDNMSDSFYVTWGARHNSGARAAPGQPLPPHGKPLGKLNSTDLKDVIKKGLIHYGRDNQNLDILLFHEVLEYMSRIDRVLSFPGGSLLLAGRSGVGRRTITSLVSHMHGAVLFSPKISRGYELKQFKNDLKHVLQLAGIEAQQVVLLLEDYQFVHP-TFLEMINSLLSSGEVPGLYTLEELEPLLLPLKDQASQDGFFGPVFNYFTYRIQQNLHIVLIMDSANSNFMINCESNPALHKKCQVLWMEGWSNSSMKKIPEMLFSETGGGEKYNDKKRKEEKKKNSVDPDFLKSFLLIHESCKAYGATPSRYMTFLHVYSAISSSKKKELLKRQSHLQAGVSKLNEAKALVDELNRKAGEQSVLLKTKQDEADAALQMITVSMQDASEQKTELERLKHRIAEEVVKIEERKNKIDDELKEVQPLVNEAKLAVGNIKPESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREDIATFDARNISKEIRESVEELLFKNKGSFDPKNAKRASTAAAPLAAWVKANIQYSHVLERIHPLETEQAGLESNLKKTEDRKRKLEELLNSVGQKVSELKEKFQSRTSEAAKLEAEVSKAQETIKAAEVLINQLDREHKRWNAQVVEITEELATLPKRAQLAAAFITYLSAAPESLRKTCLEEWTKSAGL-EKFDLRRFLCTESEQLIWKSEGLPSDDLSIENALVILQS-------RVCPFLIDPSSQATEWLKTHLKDS--RLEVINQQDSNFITALELAVRFGKTLIIQEMDGVEPVLYPLLRRDLVAQGPRYVVQIGDKIIDYNEEFRLFLSTRNPNPFIPPDAASIVTEVNFTTTRSGLRGQLLALTIQHEKPDLEEQKTKLLQQEEDKKIQLAKLEESLLETLATSQGNILENKDLIESLNQTKASSALIQESLKESYKLQISLDQERDAYLPLAESASKMYFIISDLSKINNMYRFSLAAFLRLFQRALQNKQDSENTEQRIQSLISSLQHMVYEYICRCLFKADQLMFALHFVRGMHPELFQENEWDTFTGVVVGDMLRKADSQQKIRDQLPSWIDQERSWAVATLKIALPSLYQTLCFEDAALWRTYYNNSMCEQEFPSILAKKVSLFQQILVVQALRPDRLQSAMALFACKTLGLKEVSPLPLNLKRLYKETLEIEPILIIISPGADPSQELQELANAERSGECYHQVAMGQGQADLAIQMLKECARNGDWLCLKNLHLVVSWLPVLEKELNTLQPKDTFRLWLTAEVHPNFTPILLQSSLKITYESPPGLKKNLMRTYESWTPEQISKKDNTHR-AHALFSLAWFHAACQERRNYIPQGWTKFYEFSLSDLRAGYNIIDRLFDGAKD--VQWEFVHGLLENAIYGGRIDNYFDLRVLQSYLKQFFNSSVIDVFNQRNKKSIFPYSVSLPQSCSILDYRAVIEKIPEDDKPSFFGLPANIARSSQRMISSQVISQLR-------------ILGRSITAGSKFDREIWSNELSPVLNLWKKLNQNSNLIHQKVPPPNDRQGSPILSFIILEQFNAIRLVQSVHQSLAALSKVIRGTTLLSSEVQKLASALLNQKCPLAWQSKWEGP--EDPLQYLRGLVARALAIQNWVDKAEKQALLSETLDLSELFHPDTFLNALRQETARAVGRSVDSLKFVASWKG--RLQEAKLQIKISGLLLEGCSFDGNQLS------ENQLDSPSVSSVLPCFMGWIPQDACGPYSPDECISLPVYTSAERDRVVTNIDVPCG-GNQDQWIQCGAALFLKNQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A9C9-1", "uniprot_id": "A0AB13A9C9_DANRE", "id": "A0AB13A9C9-1", "name": "Cytoplasmic dynein 2 heavy chain 1", "aln": "MAPGTDDPRKLFILTTAGNYFSLDTAAS----LSSCRPLDNFLDDGNEFLLSVTRQSEELQFSNKLENMDGDGRVLVFFKPHPCVVS--EENLQRCILVSSMLESPISTLYQALRQVYSPVLLQDDKWSQSFDSKLQSLLSDLEIGLGSVLRHSDTKGSGKRSNSEMDVSNIMTPLDEFSFWADVS-RSGQKSSERDRATHFCELFTTIEKDYSNLDSFS-LVEVLDLIENTREAVDDVWKQNEHTPYPETRMIRLMDVIGGALGRFVQRKLSDLRLWEDPYFTVREGLKGGVAVCEQWVAACEHLTGQVWKRYAPHQWTGEKHRPQGLHSLAQRLEEVVQVRSVCEKLQRLLSGGKQ-QISAARVYQPFTGLNPIHYNPYTEPLWRAAVSQFDRLIAPAEQEAAGKLKTFIIDAQDSPQQLLQVFQKHRDLIKRATISKELQPERETLLTRLLDYNKGLRADFESRCHGTPGEKTGPLAGRNLPEVVNNIVWVRQLLLKVEDSLKMADALLSDLSGFQPLLRFSDDLQEQLRSYEQEQFEDWTRDLLSGLSDPKSGISLQASNRVMELDHMDGKLKIQYSDRLVSLLREVRQLSALGFTIPAKIQQAANTAEKFYRQAIILKQVAHFYNTIDQQMIPSQRPMMLGCALAFEQVIKQNPRSQSRDEGGKLQMTWENPKELEQYISKLQSAAERLSTENRKLRKWHTDFTDKVVGLMGVDLLRQQQRWKDGLQDLRAGFATLESQGFGAGDMRAWRQHWNHQLYKALEHQYQVGLEALNKNLPEINIDLVFKQGRLQFRPAFEEVRAKYYREMKRFISIPNQFKGVSETGEEPIFTRMIERNASGFLTIFSKAEHLFSRLSHLLDKFKDWVVVGQVDVEVLVEKHLHSVQDWERNFKALKAKGKEAERLPSSEK-VDCITVNCEPVRVSVDDLIQRLFDALLASLRRSIQGHIQVIDSFVNGAMETLSLRPESIDEIGEANAKHSQLQTQKPEVLPQFQQAEEKNRLLRSVAGGGLDTISSLRAKWDKFELMMESHQLMIREQVEVMKGNVESRVQVYQQDLQKFRARWDQLKPGNDIIESGDHEALQRCVQIIRERQAEFSELENTRTKLMEDCEHFNLSSPDGTLA--SDTLRDLQDCSQMWELYEEFHSGLEEIAQHDWISFRSKTHVFEEFLFAWHDRLRKLEEHSSMSVKLQKEVDRYKAVVPVLKYVRGEHLSQEHWLDLFRLISLPRGSTLETLQFRDLLRVADNIIDKTLELKDLNSRAQAEVSIREALRELELWGAGASFTLTDYTDTQGCSLPVIKDWRDVVNQVGDNRCLLQSLKDSPYYLRFQDKVSLWETRLADLDEYLHNLNTIQRKWVYLQPIFGRGALPREQARFQRVDQDFRAIMSDVQRDSRVVSLTTRAGIRNSLVTILDQLQRCQKSLNEFLEEKRSAFPRFYFIGDDDLLEILGQATN-PTVIHTHLKKLFAGISSVEFDQSFQ-----------SITAMKSLEGETVPLINTICISNDVEVWLSALAAEMKNTLKHLLCECVNAGK--KGNVDP---TRFPSQVLCLAEQIEFTAAVEISIRQQSLHQLEQQLTAKLENYTSVDTSTDN--TTESRVLQMKLKALILDVIHNISLVQSLREAQINSTDDWVWKKQLRFYLN----------ADQSCSIQMVDADFRYTYEYQGNAAKLVHTPLTDKCYLTLTQAMKMGLGGNPYGPAGTGKTESVKALGGLFGRQVLVFNCDEGIDVKSMGRIFVGLVKCGAWGCFDEFNRLEEAVLSAVSMQIQDIQNSLKNHRSTCQLLNKEVDLDPNSGIFITMNPAGKGYGGRQKLPDNLKQLFRPVAMTSPDNELIAEVILYSEGFKEGKALGRKLVAIFNLARELLTPQQHYDWGLRALKTVLRGCGSLLQLQRLN--NNPLKE---SGLVVQALRLNTMSKLTFADSSRFDALVRDVFPGVDFKDVEYETLKSALLAVYEEAHLEIIPSQLKKAVELYEQLRQRMGVVVVGPSGAGKSTLWRMLRAALGKTGRLVKQYTMNPKAMPRQQLLGHIDMDTREWSDGVLTSSARQVVREPQEVNSWIICDGDIDPEWIESLNSVLDDNRLLTMPSGERIQFGPNVNFLFETHDLSCASPATISRMGMIFLSDEDTDVGSLVKSWLKREDEDCRMNLENWLNDYFHRALEWVLKQSDFVVDTSLVGTVLNG--LSHLSGVRERGEFIMGLIRGLGGNLTLKCRQDFAKEVLSWARESPPDPRKPLDTYYDQASGRLCVYELQRGEGVCEEELSDPHNLPVIHTPDTQRSLHSFSPWLSAN--HRQPFLLVGPEGCGKGMLLRCAFSQLRSTQVSVVHCSAQTSSRHVLQKLQHTCLLISSNTGRVYRPKDCERLLLYLKDINLPKPDKWGTSNLIAFLQQVLTYQGFYDENLEWVGLENIQIVASMSAGGAVGRHTLTSRFTSIVRICTIDYPDREQLQTVYSAYLKPVLQRTLGNDPTWSSSGK-IHQLAGSLVQVYEQVKAKFS--VDDHSHYLFTPCLLTEWVLNLLRYDLSAGKS--VVDSVLEVVVYEARRLFRDRIVSSKDLNVFDNILSSIIRGDWGTDTLDNMTDVYFVTWAASHEGR---SPGQPLPPHGRKLARLNASDLSEIIHKGIVLYGRDNRELDILLFPEVLDYMSRVDRVLTSPGGSLLLAGRSGVGRRTATCVVSHMHGATLFTPKISRSYSLKHFKSDLKTVMHSAAVDGQQVVLLLEDHQFVHP-SFLEMVNSLLSSGEVPGLYSTEELEPLLASLKDQASQDGFTGPVLNYFSHRVQQNLHVVLIMDCTNEHFTINCESNPALYRKCSVQWMESWSDSSMKKIPEMLLSRIEEDEKTEDKQRK-KKKSASVHTELYRSFLAIHESCREFGATPSQYLNFLQVYQSIYSSKRKELTHKQQHLQAGVAKLNEAKALVDELKRRAAEQSSLLKTKQAEADAALQEITTSMQNASDQKTEMEKIKERMAHEVSKIEERKKKIDEELREVQPLVDEAKQAVGNIKSESLSEIRSLRMPPDVIRDILEGVLRLMGIFDTSWVSMKSFLAKRGVREEIATFDARSITHEIRQSVEELLHRNKASFDPKNAKRASAAAAPLAAWVKANVQYSHVLEKIEPLQTEHAGLMENLRKTENRKNRLEKELNSVGEKVLELKEKFQCRTTEAAKLESEVSRAQETISAAEKLLQQLDGEHTRWTAQVDEISEELDTLPKRAQLSAAFITYLPAAPEDQRRSSLDHWMSSSGL-QKFDLRHFLCSESEQLIWKSEGLPSDDLSMENALVILQINEFRSRSASCPFLIDPSSRATEWLQTHLKAH--RLEVINQQDANFMTVLELAVRFGKTLIIQEMDGVEPVLYPLLRRDLIAQGPRYVVQIGDKVMDYNEDFRLFLATRNPSPFIPPDAASVITEVNFTTTRAGLRGQLLALTIQQEKPELESQKTKLLQQEEEKKIQLAQLEESLLETLATAQGNILENKELIESLNQTKASSALIQQSLSQSHRLQTSLDQERDAYLPLAETASKMYFVITDLSKINNMYRFSLASFLRLFHRALQTKQESESTDVRISTLESSLKNMVYEYICRSLFKADQLMFALHFVKGMSPELFQENEWDVFTGLVVGDMVRKTDSQKSLREQFPSWIDQERLMAVALIKSTFPVLYQSLCLSDADLWLTFLRSSCCEQEIPLPVAKKISLFQQMLVVQALRPDRLQSAMAVFASQALGMKQLSPPPLNLKHLYEETLETEPVLLIISAGADPSQELQELAGNIVGRENYHEVAMGQGQADVALQALRECVRSGDWLCLKNLHLVTAWLPLLEKELNSMKPKAGFRLWLTAEVHPKFTPILLQSSLKITYEAPPGLKKNLKRTYESWSAEQISKGGLLAR-AQSLFCLAWFHAVCQERRNYIPQGWTKFYEFSLSDLRAGFEIIDRLFEGGKA--FQWDFVDGLLEN-IYGGRIDNVCDLLVLRSYLQQFFNAQLLSQS--RKKTHAFPAQIHLPNSCSIADYRVVVDALPEDDRPSFFGLPANIERSSQRIISSQVISQLR-------------ILSRPVAAGSKFDREIWSSALSPVLNLWKRLNQGSSLIHQKVTLPSESVGSPIFSFIQLEQFNAVRLVQSIHQSLASLSKVIRGTSLLTADVHKLATALLNQECPLSWQNKWEGP--EDPMQYLRAVVSRALAIQGWVERAERGGLLSEMLDLSELFHPDTFLNALRQETARLMSCSMDSLKFVTTWRG--QITEAKLQVKVGGLQLEGCSFDGNRLS------ESHHDSPSVSSVPPCHMAWIPQSAMGCYSPDECISLPVYSSAERVCVVTNVQLPCA-GDHDTWIQSGAALFLKQQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E8P6-1", "uniprot_id": "Q0E8P6_DROME", "id": "Q0E8P6-1", "name": "Dynein heavy chain, cytoplasmic", "aln": "-----MTQRTKFIINTSVEYFSARLPGSELDEQTAMILEFLEQEELTVISAVHSRSDGRIRFHHRIPNEE---LCLLFYKVPQVGHHRKEDGSEPLLGILTLEGGMVKSIYNSVSRVFSPSAN--SARRSEYGPELSGILENLHQNLGSSLGLPQSG--------------ITSLRNEIKYWQQKLGQKSSSRLDREAAQVFIGVLENMEKQISTIDGANPSGTIEEFLDHAHTNLDELWRLP--YNYPQQRMADLLDIIGKRLLEVCLTQLLAEDVWSLNSSHVNNLMSQSIDTVDAWIQLCDSLTRLFWPNYVKHPWLGDSHVPKRGQQFKERLSEIRSIKQLYKQIATLLEDTELQEMFQE--QAPFTEFNIFDTSSLGQNKWHKALQHFEQVLQPIDERIAAALKRQLHNHLSNPRQVIFIFSKYETLIQRPAVLELLTIEREQFLQSLHILLQDLRKAMVDSNMEPDTG--------HLSVICNECRWLKVVQHQIQEIEKVS-HLISGREGFDKINKAVQEIKEETESLLRTNFEIWSGQCSTAVKSGELRLRDDQAVVKFEKEGRQ-LMRVTFNPKLVTFCQDVREFENLGYNVPLELRAAATHAAKYMCYARRLQQIATFHNTIGDRMIPCQRPIMLKNALELQRLVQ------------SETVAWQDESSVQRYVDILQAAVSKLSSDNTLLVGYHEQAKRSVLKLMSTDLFTQNQIWKDELRHLRELVATLERQGYT--HLDAFKLHWDHQLYKVLEYQYILGLLDMNNKLPDIHVKLVLRQRELVFSPPEEEIRELYFSQLRRFIERPCNFHGLSEHS-QELFKSMVTVNRHHFGPLYQRAAELFDKLQDFKTIWLPWIALGCVDVDQLCGIHLNEAGDWDRNFRSCKHFSQQLAKLQQAEESIDCIVINVLPLRSDIEYISRRYWESLANSLRTAILTDVSLIQEFLQSALQFLQNVPMDEGSISQSGMKYEKIMSKLPQIEKTLEAVRAKDSCLGGWCKERVTALSGILLQWEQLQPLLENHAVILQRQVDMIKNQAETQLQNLKNEAEKFLLRWESTISELEANEHS-------TLDVFKERRLHWQQLQEKKTQLLEECSKFNMEFPAEMLTPFTEIEEQMEKQSKQWQVYDSFLTELQPVLHEEWAIYRRRPYVLNEFIGKWEGSVHASIDLPSK--RIRQQVEQLQSALPILQQLQSESLSERHWARIFQLLNHKETKPLHSILLQDILQDFDVLQSAAQEISSIVRQASSEQIVRQALIELDQWSVTAQLKLITRTDASGQSVSLIKDYQEVLNKIGDNQSLLQSANNSAAFESFSDQAELWESRLNTLDALLSSLNHSQRRWVYLEPVFGSGTLQHEQALFKRIDKDFRFVMREIEMDPRVTSLTKINNITTIVNALETQLARCQQNLMSYITDKRNSFPRFYFLGDDDLLELLGQASKDAEVIQRHIRKLFPGCHSLSIRQVGPNPATSSDVNQYSITSVHSAEGDELKLSQPVEMKGDIERWLNQLVTVVQDTLRDQIYECYTGTTGGSDNLDEKILKKYASQVLATARALHFTRQAEQAIGSMSLGKLKQQLKDEITHLAALKNKSEN-----GTLISLKLRALLLDLVHYSGVTEQLQKHNVVHTSDWHWLCQLRYYLGKKGGTSGEVNANRQVCVRMVYAEFEYAYEFLGQASKLVHTRLTHRCYLILTQAMHMGLGGNPFGPAGTGKTECVKALGAMLGRLVLVFNCDENVDTESMSLILTGLARCGAWGCFDEFNRLQEATLSSISMLIQPIQSALKERANSVQIGERQIQLNQHCGIFVTLNPAGAEYGGRQKLPGNIQALFRPIVMQQPEPGEIARVMLFVEGFTEASAIASRIVELFELSGKMLSAQRHYDWGLRELKTVLMVCGEGLRDQLTSEDNNQSSANFEMSVVVRCLRSSTMSKLAPHDVNRFEMLLRNVFPEIGSSPAPETQLHQSLSAAFAQLGLCRSERQIEKALQLHEQLQKRMGVVLVGPPGCGKSTIISLLKQALCGT--QLKVHTISPKSMSRIQLLGRLDADTRQWQDGVLTHTAVAVNQESSQVHSWIVCDGSIDPEWIEALNSVLDDNKLLTLPSGWRIQFGSNVNFIFETDDVRHASPATISRMGIVNMSYDYYPADGILKHELSKEP--YGDLLQSYVDGNFQYAVNWIESQLLLTHLPGINRAHLLRSLLLQLHGTQSLEEYGAATLRALFGYMPNDRQREFAQLILKHANLYVANPNYAELTHYESSRNSLEQYAVDAIETPEKGSQ-------LIITSYMKSYLDILETLLKTQGTRLPPFMLIGPSGSGKTLLLQRAVLENSGYQLATINCSTQLTPRYILHTLKTHCVTVSGIKGREYRPK-QARLVLFMKNLDLCQQDSWGACEVVELLFQLAQRGGFYAENLEWIGVSGLQLCASIGG----NTGKIAPRYFAINQFVRVSRPTSQDMLEIVQRRLEPLLEEHFRGSENRGRSGVNLQHVSESLMDCFEKLQATFTNVGGRQAHYQFSPKCIMKLLDALVFYPAS---------DFNEALYCELLGMFRDRLISEEHVQQFEGILKQTMRKYYGKEKVFFVPK---------------------SPKSRGHLHCLTHDEWMEEVQRQVTICNTENYSITAPITEELLSHVARITRVLSRTDAHMLILGQSGGRHLDAIFTAATFQEAKVVTLQGGPSYDLTDFYNDLKVAMQTAALEQQMSYLLIEQCWLSYVPDILKPIEALLEGSEILELFG-DDLETVASTLKQAAQLEGYQESMGTYFLKRARDYLHIIIVLDPNSAKVQDYFNNFPALHRQMDLLYVRGESRETIAILPKQFIELLNESIAGGGSGRGKVPTCS--------HFADISDELPSE-ETSQRYYQLIRTYFHMYNNAANEIDQRLGKLQMGVDKLASAHALVDTLKSNAAAQEQALGEKRQLANEALEMISFTMRNANEQKSSMLELKQQTQKSSEQLKIRQKEIQQELAEVEPILAEASNAVGQIKSEALSEIRSLRAPPEAVRDILEGVLRLMGIRDTSWNSMKTFLAKRGVKEDIRSLDPARISPENCEAVERLLLAKGDSYEAKNAKRASAAAAPLAAWVQASVRYSRVIQSIKPLEREQNELQKNLNAAEDEMQELASGLDDVDKRVKQLSAKLQTYTQEAAVLELKLQEASGTLQAAELLVEKLSAEYTTWSLQLTELKKAHKTLDAKTLLIAIAINYCAGLGLEQRCSSLKRLAADFHLPSDFDLRGSLLTEQQQIIWESQGLARDAQIIESAALLREMLSLPYGACPIPLLLDPTQTAAAWLMAHLKGSGRPCELTTHGNDRLPYQLELAVRFGKTLLVTDCEQLRPPVLQLLQGHVFVRFNKRQLAIGSKLVDLHESFQLVLISKSHRLDLPEEQRSQLNVLKFTVTAAGLADQLMSKAIVLKNGELEQQRIELLQKEGHLLKQRMEMQDKLLEQLSKSEGDILKNEQLLESLNEIKQGSTQIDEALKQSGQIRDTLLAQFGSLRELSSRAATFYAGLIQG------YELSPLVYIELFLGALSKSQRDE------SKVYDCLVRSVYMNLARATSRDSQLSLSLWVCHQAYPDRLNPKEWELFVNNFMGSSD--GSMVLSQLGKLPDCMPKEAQLKLAMLLQLFPDLRSKLQLEKDYIWR-----GFIEAQADDVLPALGSSFQRVLIAQIFRPDLMLHQLRKVSSDLLGISPDASTQPSVEQLLQQSSCDRPILMVSHAENDPTTELRKWAN-----QKYREMAIGKGVEKRVLSEMRQAAIDGHWLCVKNVHLVPEFLTQMERELSEIQKSKDFRLWLLCESTEGFSEAAIYKCLKVRYEQPKGLKQIVMRLLQNFAAEQDQKLKNQPKSLKMRLVYFVLTAVLQQRRQFIPQGWSKYYEFGEADLKAALGILRMMDQQLNSGKCDWLLMQRLSEALAYGGRVNNQRDLEILTTYLNQFCSADVLSNR-----WSPLGLSLSIPTSGQLQDYYAALEKLPDTDEPSMYGLANQAQQQREIEQAKRVIKELRGLHYGRGLAKDSGGAGESKGNDQLTGRQKLEQQIKPLLNLWRKLAASCTIIQTMKEAKTDVGESPWALFVLAELKLGADLYGIVHQTLSQMHAWLKESQEVDGSTLR---TLAEQQIPASWLKLWPGPGSNSAVDFLRALIVRAQAAELRFR-EQMHLDFVEDINFVQVFNCENLLSCLKLLQSRKLAVSTERLELQTCGSSNLESDSSDIILKLAPLKIDGAQSGMGKSNPFYIKYKIKDEVQNVSHTTTSSSKYGKNSLYSTQNAESKPKLPLYSRSSRDKLICHLNVDIVTGTAEQILLAGTALIVEDY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. *::.*: :**. :: . : *.. : * : : : *:*:* : . . : : :: . :.::*::: :*::* . .:..:*..:*.:*. .** * .:: * : :*:.:* : : ... .:: * * :: .: :: .:*. . : :::: :: :*::*: **: ** *:*:** : .. :* :*. *.: :. .: : *: *. ** .* .*. * * . .: *: . : :**.*: :: : ::: :* : : *** .* .. .. : *: *:.:::::: * ::. *. ** : : ..*:*:: * *:. *::*.:: : * *** :* * :.:* : . :*. : *. *:: : :::: *:: *:*. ** : : .:: :: . : :*: *: : :.:.. . : : :* : : ::: :. :** : ::**::. **: :* ::: .*. * *: * *:*:* *:*:*.::** .***:** ** :::::: . ::*:: ..:: *:. ** *..:*:::* * :* .*: **. **: *:* *** *:.** .*:: **: .: *:: **:*****.**:** :** :*::**:*::.*. :* .* * *. **:* *: :::*** * :*:*:. . : :*. *: * * .::.:* .** :*. . *:.:* **:: * :* . **::**:: * .:: :* .: : :**: :* *:: :: : :: :: * **: :* .: *: *: *:: * * . .*.::. ::.:: : *:: :: .. *: * . : ::*.: :*:::: ::*.* :::: *::::*.:.::::* :: :** **:. . : * . . ::*:: .:.:*: :.:*:::* :* :. . *: . .:::. :: * .*:.* :: : :.:* :* : ::::**: *. :: : . :::.:*:: : :*:*: ::.* ** ** :*:*:. . ..*..: : *:*: * : : ::..: :*..* :*:** **: *.. * :.* *:.. :: :***:::::*::***:.**** ::*. : *.*:..:** :* ** * .** **:****:*:** *:* :**: *:::*:*** :* ::. * **.:**. .* . : :: ** ***:.* .:: :**.:******:*******:***::: . **: *::***.* *: : : **:::* **: : : . : :..::* **. *. ::.**.. : ** . .. :* . :.**:*. *. :.** .* :* . ** ::: ** :: . : :...::: . ::.:**::*:**::* .:.:.*.: :: *.** * *:*:*: ::: ::** :::.*:**: *:*.***:* **.:*** *****:*******:*********.*****.::** ********.:*.:**. *:.**.:*************:*:.**::** ** **.:**:: . :: :::::: :.***:*:**** ********.*:: ****:.* *: **.*:*: ***.:.. :. ::* :*:*: ::*:.*:******* ***** .*. *: . .: . :**:.** .****:: * .**: *:::*** : . . * :* .: : *::**::*:*** :* ***:***.*.****: :*: ** :* :*:.**:*.* ****::* ***:*.***** :* * :*..:* ***:***.*******:********:***:*** *****.****:***.*: **********:: :* : ..::* * .: *:.::.. * *::*: .* . ..: : : * :* * : :: :*.* * : . : :*:: :: *. .: . . *::: . * * :. * . :* *. : *. :.. *.:: **:*:**.*.** :**: *. : . :::.::**:* :.*::*:.*. *: :* .** **** **:*::*:::* : *.**:. :: :* *: *** *****:*:..:*: **:.. . .::.*: :* :: :. * ::: : *:.:*.. : . . *. : :: *::: :*:::*.*: . :** *:* : : : *. * . . * : * :***:::. :.:: *: **.. :: :*.: : :.. * * *. : : ::: : . :* .: : *:*.:::*: ***: ... :*: *:** : .: :: * :.: : . .*. ..* .*** .:: *.:: * **:*: : : :*: :::** ..*: *: ::**.: .**: *. :*: .: .** * :: **:::::* . :. :. ***::: : ::.. * .:: :*: ::. . * . * * :. *..:* :::.* : .. :*: :: :** ** ** .*:**** *: .*. *. * *: *: **: *: :*::*.:**:.: .:*.: .. ::: *:.:*::** **:*:: **. ***:*:.*:******** **:.:************* **** ***:*******:*:* ::*. *. * ::**.** : *::.*******:*********:*.::**:*:: *.**: *: * **. :*:. ..* . *:.*.::* :*. *:* * *** ** ::..*. *:.*** *:.:*. *: *. *: *: : ** :: * * *.* .. * ..*.. * ..**** * :*.:*:**:*:**. * :*.* :: : *:*:**:. *: ** :*** *: .: : .: ***********:: : : :.* : **: .:..: : : **.*::* :*.*:*.* ::. :* : * :. ::**.* :** .**:: :* :: :**.*: :***:* . * .:::.*** *:.::*:**:*::*:****: * .*: *:::*.:* ::: :* : .: *:. *:.:* : : *.:* ::.** **...* .* . : ..* . ** :.*. : .** ::* . : *: :: :**: *.. .:*. . ::*. : :* :* : :* * ..* :.. :* . * : :. * **::*:.* :*** : : .:.. **:. :. .:::* ::: .*:*:: . **: **:: *. : *:::*:*:* . .:. :::.. .*.***:**:*** :*. :*:**. :: . ***** .* *: : ..**: ** * ***: : * :.::.** .* : : : : *. *:**::*****:*:***. :**:*. :: : : : :* ::. * * ****::* ** :* :**:** .:.::. : .: :* * .: ** ..:: :*: *.**::**. : :. : :.:**.:** ... . .*: .. :.*:****::* ...:*: .: ** *: * . * :**:*: : :: : : ... : :* :*: * :* . * ** :..:::**.:: *: * : . : : : ::: ::*: :.:*..*: :* . * : *:: : . . .:.: :*:. * ::*.. . .: . : : : .** . .. : :. . ..:. .**:*: :.* :: :::: * : : .*:**:::: ", "identical_positions": 1178, "similar_positions": 1597, "identity": "26.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100219-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0H7-1", "uniprot_id": "BCL10_MOUSE", "id": "Q9Z0H7-1", "name": "B-cell lymphoma/leukemia 10", "aln": "MEAPAPSLTEEDLTEVKKDALENLRVYLCEKIIAERHFDHLRAKKILSREDTEEISCRTSSRKRAGKLLDYLQENPRGLDTLVESIRREKTQSFLIQKITDEVLKLRNIKLEHLKGLKCSSCEPFAAGATNNLSRCNSDESNLSEKQRASTVMYHPEGESSTAP----------FFSMASSLNLPVLEVGRTENSSFSSATLPRPGDPGAPPLPPDLRLEE----GGSCGNS----SEMFLPLRSRALSRQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95999-1", "uniprot_id": "BCL10_HUMAN", "id": "O95999-1", "name": "B-cell lymphoma/leukemia 10", "aln": "MEPTAPSLTEEDLTEVKKDALENLRVYLCEKIIAERHFDHLRAKKILSREDTEEISCRTSSRKRAGKLLDYLQENPKGLDTLVESIRREKTQNFLIQKITDEVLKLRNIKLEHLKGLKCSSCEPFPDGATNNLSRSNSDESNFSEKLRASTVMYHPEGESSTTP----------FFSTNSSLNLPVLEVGRTENTIFSSTTLPRPGDPGAPPLPPDLQLEE----EGTCANS----SEMFLPLRSRTVSRQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F8A6-1", "uniprot_id": "E7F8A6_DANRE", "id": "E7F8A6-1", "name": "B-cell lymphoma/leukemia 10", "aln": "MDVTH--LTEDEMADIKKEAIERLRPYLVDKIIADRHFDYLRSKKILTREDTEEISCRTTRGKRTSKLLDILAENPRGLDMLIESIKWGRTLNFIIARITDEVQRVKNERLEALK-AGSNSAYPTTKGATNDFSKMDSDYDKYS------TMCLHPEGEASSSSSVATGSFNLRYSSTRGNEALMVSGGSGTMNVSSTSSILPKPGDPGAPALPEEMENDEQDMDGGVCKSAGSSGDANFQPLRSRSLSP-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . ***::::::**:*:*.** ** :****:****:**:****:***********: **:.**** * ***:*** *:***: :* .*:* :***** :::* :** ** ..*. * . ****::*: :** .: * *: *****:*::. : * .. * * . * * :*: **:*******.** ::. :* * * .: . * *****::* ", "identical_positions": 111, "similar_positions": 62, "identity": "44.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100226-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H239-1", "uniprot_id": "MMP28_HUMAN", "id": "Q9H239-1", "name": "Matrix metalloproteinase-28", "aln": "MVARVGLLLRALQLLLWGHLDAQPAERGGQELRKEAEAFLEKYGYLNEQVPKAPTSTRFSDAIRAFQWVSQLPVSGVLDRATLRQMTRPRCGVTDTNSYAAWAERISDLFARHRTKMRRKKRFAKQGNKWYKQHLSYRLVNWPEHLPEPAVRGAVRAAFQLWSNVSALEFWEAPATGPADIRLTFFQGDHNDGLGNAFDGPGGALAHAFLPRRGEAHFDQDERWSLSRRRGRNLFVVLAHEIGHTLGLTHSPAPRALMAPYYKRLGRDALLSWDDVLAVQSLYGKPLGGSVAVQLPGKLFTDFETWDSYSPQGRRPETQGPKYCHSSFDAITVDRQQQLYIFKGSHFWEVAADGNVSEPRPLQERWVGLPPNIEAAAVSLNDGDFYFFKGGRCWRFRGPKPVWGLPQLCRAGGLPRHPDAALFFPPLRRLILFKGARYYVLARGGLQVEPYYPRSLQDWGGIPEEVSGALPRPDGSIIFFRDDRYWRLDQAKLQATTSGRWATELPWMGCWHANS--GSALF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HEG0-1", "uniprot_id": "A0AC58HEG0_DANRE", "id": "A0AC58HEG0-1", "name": "", "aln": "MSEQS--------------SCALLATSCSSPISSPAQGFLEQYGYLYKDN-ETYRTAEVKTAIREFQWLSWLPVTGHLDAATLEKMASPRCGVTDAGSIDAWQDRINGIFTGRHGQHLRKKRYTQLGEKWQKKQLSYRILNWPRSLSTSQVHLAVSAAFQLWSNASGLQFLEL-HQGPADIRLAFYDGEHNDGAGNAFDGPGGALAHAFFPFRGEAHFDMSERWTLSGYKGHNLFLVTAHEIGHTLGLVHSPVRHALMSPYYKKISSNAVLSWDDITAVQQLYGKPPGDTVQQLVGRALRWTMQDWQIS--QDPRESSLTPNYCHGFFDAITTDENGAVLVFQGYRFWSVS-NGSVSDPCLLQTRWPQLSVTIEAAAFNPLDRKLYFFKGRRMWRYSGSNLDPGFPKRSSALGLPKHVDCAFFYQPLGQLVLFKGSRYLVLNPRSLSMELYYPRPLRDWKGVPREVNGALTRPDGMLYFFKEQQYWRLDIGKLRITAAGRWADSLQWIGCQKTPSLLDNEL-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : * * .. : . *:.***:**** :: :: ::... *** ***:* ***:* ** ***.:*: *******:.* ** :**..:*: :: : ****::: *:** *::****::***. *. . *: ** ********.*.*:* * *******:*::*:**** ***************:* ******* .***:** :*:***:* **********.***. :***:****::. :*:*****: ***.***** *.:* : * :: *: *. * .: *:***. *****.*.: : :*:* :**.*: :*.**:* ** ** *. .*****.. * .:***** * **: *.: *:*: . * ***:* *.*:*: ** :*:****:** ** .*.:* ****.*:** *:*.**.***.**** : **::::***** .**: *::**** .* *:** :: * .. * ", "identical_positions": 258, "similar_positions": 134, "identity": "49.43%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100226-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZ42-1", "uniprot_id": "D3ZZ42_RAT", "id": "D3ZZ42-1", "name": "Matrix metalloproteinase-21", "aln": "MLAVSDLRLTMLLCWLVTPQPAQPERLFHSRDRSDLEPSPLSRAKPIADLHAAQNFLLKYGWSEV-----SSPKESAG-------------------VPVGFTLAQAVRRFQKANRLPASGKLDSPTLAAMNKPRCGVPDTRLPLQDAL---------PTPPALPTPLGLQPRARQKRFLQMLLPKPGGKQEGRSDTGASRVFSKKTLTWRLVGDAYSSQLSGDEQRYIFRLAFRMWSEVTPLDFREDLTAPGTMVDIKLGFGRGRHLGCPRVFDGSGQEFAHAWHLGEIHFDDDEHFTPLSSDTGISLLKVAVHEIGHVLGLPHTYRVGSIMQPNYIPQEPAFELDWSDRKAIQRLYGSCEGSFDIVFDWIRKERNQYGEVRVRFNTYFFRNSWYWLYENRNNRTRYGDPLQILTGWRGIPMQRIDAFVHVWSWGRDERYFFKGNQYWRYDSENDQAHTQDEQGRSYPKLISEGFPGIPSPLDTAFYERRQQLIYFFKESLVYAFDVNRNQALSSYPKKMSQVFPAIMPQNHPFRNLDSAYYSYAHNAIFFFKGNSFWKVVSDKDKQQDSRLPLNGLFPKQSVSGKWFDVCDVHTSTLNM----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K3F2-1", "uniprot_id": "MMP21_MOUSE", "id": "Q8K3F2-1", "name": "Matrix metalloproteinase-21", "aln": "MLAASVLRLTLPLCWLVAPQPTQPERLFHSRDRSDLEPSPLSQAKPIADLHDAQSFLLKYGWSEI-----PSPKESAG-------------------VPVGFTLAQAVRRFQKANRLPASGELDSPTLAAMNKPRCGVPDTRLPPRAAL---------PTPPALLTSLGLRPRARQKRFLQMLFPKPDGQQEDASDTGASRAFSKKTLTWRLVGDAYSSQLSGDEQRYIFRLAFRMWSEVTPLDFREDRTAPGTMVDIKLGFGRGRHLGCPRVFDGSGQEFAHAWRLGEIHFDDDEHFTPLSSDTGISLLKVAVHEIGHVLGLPHTYRVGSIMQPNYIPQEPAFELDWADRKAIQRLYGSCKGSFDTVFDWIRKERNQYGEVRVRFNTYFFRNSWYWLYENRNNRTRYGDPLQILTGWRGIPTQSIDAYVHVWSWGKDERYFFKGSQYWRYDSENDQAHTEDEQGRSYPKLISEGFPGIPSPLDTAFYDRRQQLIYFFKESLVFAFDVNRNQVLNSYPKKMSQVFPAIMPQNHPFRNLDSAYYSYAHNSIFFFKGNSYWKVVSDKDKQQNTRLPLNGLFPKKPVSEKWFDVCDVHTSTLNM----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N119-1", "uniprot_id": "MMP21_HUMAN", "id": "Q8N119-1", "name": "Matrix metalloproteinase-21", "aln": "MLAASIFRPTLLLCWLAAPWPTQPESLFHSRDRSDLEPSPLRQAKPIADLHAAQRFLSRYGWSGVWAAWGPSPEGPPE-------------------TPKGAALAEAVRRFQRANALPASGELDAATLAAMNRPRCGVPDMRPPPPSAP---------PSPPGPPP----RARSRRSPRAPLSLSRRGWQPRGYPDGGAAQAFSKRTLSWRLLGEALSSQLSVADQRRIVALAFRMWSEVTPLDFREDLAAPGAAVDIKLGFGRGRHLGCPRAFDGSGQEFAHAWRLGDIHFDDDEHFTPPTSDTGISLLKVAVHEIGHVLGLPHTYRTGSIMQPNYIPQEPAFELDWSDRKAIQKLYGSCEGSFDTAFDWIRKERNQYGEVMVRFSTYFFRNSWYWLYENRNNRTRYGDPIQILTGWPGIPTHNIDAFVHIWTWKRDERYFFQGNQYWRYDSDKDQALTEDEQGKSYPKLISEGFPGIPSPLDTAFYDRRQKLIYFFKESLVFAFDVNRNRVLNSYPKRITEVFPAVIPQNHPFRNIDSAYYSYAYNSIFFFKGNAYWKVVNDKDKQQNSWLPANGLFPKKFISEKWFDVCDVHISTLNM----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0N9E2K8-1", "uniprot_id": "MMP21_DANRE", "id": "A0A0N9E2K8-1", "name": "Matrix metallopeptidase-21", "aln": "MLTVIRRIFIIQTFIFIT-----AEKIFHSRDHSDVLNN-IHQAELITDTDTAQRFLSKYGFIKAAGSEESQLSESSGDLDFSLSLDLHEGGTTSGSSSSDLQFVSALRDFQRLSDLPVTGVFDDATKAAMNKPRCGVMDDDQELKDVTGSNSTRNHIRTSTNTSHNHEHQAPVRKKRHLSALLKNTSLQKRDVSKWTGHMAFSKSVLKWRLIGEGYSSQLSIQEQKYIFRLAFRMWSEISPLQFIEDLHSPLENIDIRLGFGTGRHLGCSQRFDGAGREFAHAWFLGDIHFDDDEHFTVPNTGSGISLLKVAVHEIGHVLGLPHIYRPGSIMQPSYLPQDAGFEIDWMDRKSIQRLYGVCTGRFSTVFDWIRKEQTPYGEVVVRFNTYFMRDGLYWLYENRNNRTRYGDPVAVQVGWHGLPSGGVDAYVHVWNRKTDAVYFFKGMQYWRYDSENDHVFSHAPDGRLYPRLISEDFPGVSGPLDTAYYDRRDAHIYFFKGSQVFRFDVRMRRLASSSPQEMTEVFPAIVSGDHPVRSLDAAYFSYTHNTVFLLKGSLFWRVLSGKERRRRAFLPMNGLLAHRRVHEQWFDICDVHSSSLRTTRRR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:. : : : .* :*****:**: . : :*: *:* . ** ** :**: .. . .. . . :..*:* **: . **.:* :* .* ****:***** * . :.. :. *:. : . . : .. .. . .*** .*.***:*:. ***** :*: *. ********::**:* ** :* :**:**** ******.: ***:*:****** **:********** .:.:******************** ** ******.*:**:..**:** ***:**:*** * * *. .*******:. **** ***.***:*:. ****************: : .** *:* :**:**:*. * ***:* *******::*:. :. :*: **:****.***:..*****:*:**: ***** * *: ***. .: .* *:.:::****::. :**.*.:*:**:**::*::*::**. :*:*:..*:::: : ** ***:.:: : :***:**** *:*. ", "identical_positions": 267, "similar_positions": 162, "identity": "44.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100302-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LED2-1", "uniprot_id": "A0ABK0LED2_RAT", "id": "A0ABK0LED2-1", "name": "von Willebrand factor A domain-containing protein 2", "aln": "MMPKPFFTVTLPCVIGGCSLARGSSSLLVCSVPDFASPSMFSLWRSNNMPPYLFLPAIYTLLFSRVSLSSSLQEVHVSRETTGKIAVASKLIWCSAAVDILFLLDGSHSIGKGSFERSKRFATALCDALDISPGRVRVGALQFGSTPHLEFPLDAFSTRQEVKEIIKKLVFKGGRTETGLALKHLL-RGLPGGRNGSVPQILIIITDGKSQGHVALPAKQLKERGIVVFAVGVRFPRWDELLTLASEPKEQHVLLAEQVEDATNGLLSTLSSSLLCTTADPDCRVEAYPCERRTLETMRELASNALCWRGSRQADTVLAVPCPFYSWKRVFQTHPANCYRTICPGPCDSQPCQNGGTCIPEGVDRYHCLCPLAFGGEVNCAPKLSLECRIDVLFLLDSSAGTTPEGFRQAKAFVKRFVQAVLSEDSRARVGVASYSRDLMVAVPVGEYQHVPDLVRILDSIPFSGGPTLTGSALLQVTEHGFGSASRTG--QDRPRRVVVLLTESHAQDEVAGPADHARARELLLLGMGNELMRAELERITGSRKHVIIHTDPRDMFSQIPELQRRLCSQPRPGCQAQSLDLVFLLDASASVGGENFAQMQSFIRKCTLRFDVNPDVTQVGLVVYGNQVQTAFGLDTHPTRASVLRAMSQAPYLGGVGSAGTALLHIEDKVMTVQRGARPGVPKAVVMLTGGSGAEDAAVPAQKLRDNGISVLVMSVGAVLKEAVRRLAGPRDYLIHVAAYTDLRYHQDTLIEWLCREAKRPVSLCKPSPCMNEGTCILKNGSYRCECWGGWEGPHCENR----VLRGDAPMAHSFRREPTGRQQPTPSQQAPKHVGV--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q70UZ7-1", "uniprot_id": "VWA2_MOUSE", "id": "Q70UZ7-1", "name": "von Willebrand factor A domain-containing protein 2", "aln": "------------------------------------------------MPPLLLLPAIYMLLFFRVSPTISLQEVHVNRETMGKIAVASKLMWCSAAVDILFLLDGSHSIGKGSFERSKRFAIAACDALDISPGRVRVGALQFGSTPHLEFPLDSFSTRQEVKESIKGIVFKGGRTETGLALKRLS-RGFPGGRNGSVPQILIIVTDGKSQGPVALPAKQLRERGIVVFAVGVRFPRWDELLTLASEPKDRHVLLAEQVEDATNGLLSTLSSSALCTTADPDCRVEPHPCERRTLETVRELAGNALCWRGSRQADTVLALPCPFYSWKRVFQTHPANCYRTICPGPCDSQPCQNGGTCIPEGVDRYHCLCPLAFGGEVNCAPKLSLECRIDVLFLLDSSAGTTLGGFRRAKAFVKRFVQAVLREDSRARVGIASYGRNLMVAVPVGEYQHVPDLIRSLDSIPFSGGPTLTGSALLQVAEHGFGSASRTG--QDRPRRVVVLLTESRSQDEVSGPAAHARARELLLLGVGSEILQAELVKITGSPKHVMVHTDPQDLFSQIPELQRRLCSQPRPGCQAQSLDLVFLLDASASVGRENFAQMQSFIRKCTLRFDVNPDVTQVGLVVYGSRVQTAFGLDTHPTRAAVLRAMSQAPYLGGVGSAGTALLHIEDKVMTVQRGARPGVPKAVVMLTGGSGAEDAAVPAQKLRGNGISVLVMSVGAVLREAVRRLAGPRDSLIHVAAYTDLPYHQDMLIEWLCREARLPVNLCKPSPCMNEGTCVLKNGSYRCECRGGWEGPHCENR----ILRGDAPMARSFHQEPAGLQGPTPSQQAPKHLRIGKALSSAK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5GFL6-1", "uniprot_id": "VWA2_HUMAN", "id": "Q5GFL6-1", "name": "von Willebrand factor A domain-containing protein 2", "aln": "------------------------------------------------MPPFLLLEAVCVFLFSRVPPSLPLQEVHVSKETIGKISAASKMMWCSAAVDIMFLLDGSNSVGKGSFERSKHFAITVCDGLDISPERVRVGAFQFSSTPHLEFPLDSFSTQQEVKARIKRMVFKGGRTETELALKYLLHRGLPGGRNASVPQILIIVTDGKSQGDVALPSKQLKERGVTVFAVGVRFPRWEELHALASEPRGQHVLLAEQVEDATNGLFSTLSSSAICSSATPDCRVEAHPCEHRTLEMVREFAGNAPCWRGSRRTLAVLAAHCPFYSWKRVFLTHPATCYRTTCPGPCDSQPCQNGGTCVPEGLDGYQCLCPLAFGGEANCALKLSLECRVDLLFLLDSSAGTTLDGFLRAKVFVKRFVRAVLSEDSRARVGVATYSRELLVAVPVGEYQDVPDLVWSLDGIPFRGGPTLTGSALRQAAERGFGSATRTG--QDRPRRVVVLLTESHSEDEVAGPARHARARELLLLGVGSEAVRAELEEITGSPKHVMVYSDPQDLFNQIPELQGKLCSRQRPGCRTQALDLVFMLDTSASVGPENFAQMQSFVRSCALQFEVNPDVTQVGLVVYGSQVQTAFGLDTKPTRAAMLRAISQAPYLGGVGSAGTALLHIYDKVMTVQRGARPGVPKAVVVLTGGRGAEDAAVPAQKLRNNGISVLVVGVGPVLSEGLRRLAGPRDSLIHVAAYADLRYHQDVLIEWLCGEAKQPVNLCKPSPCMNEGSCVLQNGSYRCKCRDGWEGPHCENR----FLRRP-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA70RFA5-1", "uniprot_id": "A0AA70RFA5_DANRE", "id": "A0AA70RFA5-1", "name": "", "aln": "------------------------------------------------MSSSSRQNLFFMLLFGQVWSIFSVQEIQTDLDTIMKINAAGEMMQCSAAMDILFVMDSSYSVGKGGFERSRHYMLKLCEALDVRQDKVRVGVVQFGSTPKLEVSLDSYKTKEELKKKLKKIHYRGGSTQTGLALKFVLRKGFSGGRNSSVPRVVVLLSDGKSQGAVQLPASELKLSGVLLFAVGIRYPRWDELRELASGPSDSHVFFAEHFSDAVNGLFTSLTTSSVCMSIPSGCKVESYPCVQKTLETVKQLQGNFVCWKGSK-GYSAYTSLCPHYRYNKVYRQHPAVCHRTICPDPCDSQPCQNGGTCVSEGLDKYRCECPAGYANDPNCAPILSFDCSVDVLFLLEGSSALTLEGFLRFKSFLKRFMQAVLSSDTPVKMGLAQYGSDVKIEARIGEHRDPVKLIQAVEGLQYRGGQTKTGNALRYITRHGFQSTPVFADVQDDLPRVVVLLTGTPSADHVVEPAKYARDREIFIIGVAPEGMRAEINNITGNPQRTIMYQSPDRLSSKIPELRAKICSVDNQGCLGQALDLVFVLDASSGVGKENFIHFQDFVRSTSVQFDINRDVAQVGLVVYGRRPVTVFDLDKYNSGSAVLRAVGDAAFLGGKASVGSALLHVLSQSLTVGKGARPGVNKAVVVLTDGTGVEDAAVPAQKIRDSGVSIFLIGVGDIQQELLLRISGSEDHMITVPSYDDLKYSEDVLVQMVCSDVKKPVNLCSPNPCMNDGICVMLNGSYRCECR-GWKGPHCETRSREQPSRGDLPKPAGLRRRQPKTEKELLQRYKEQRRRHTSKTQIR-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. . :** :* .:**::.. :* ** .*.::: ****:**:*::*.* *:***.****::: *:.**: :****..**.***:**..**::.*::*:* :* : ::** *:* **** : :*:.****.***:::::::****** * **:.:*: *: :****:*:***:** *** * **::**:..**.***:::*::* :* : ..*:**.:** ::*** :::: .* **:**: :. : **.* :::*: *** *:** **.*************:.**:* *:* ** .:..: *** **::* :*:****:.*:. * ** : * *:***::*** .*: .::*:* *. :: : . :**::. .*: ::.: : ** * **.** :.:** *:. . ** ******* : : *.* ** :** **::::*:. * ::**: .***. ::.::: .* : .:****: ::** . ** *:*****:**:*:.** *** ::*.*:*. :::*::* **:******** : *.*.**. : :::***:.:*.:*** .*.*:****: .: :** :****** ****:**.* *.*********:*..*:*::::.** : * : *::*..* :* *.:* ** * :* *:: :* :.: **.**.*.****:* *:: ******:* **:*****.* * ", "identical_positions": 334, "similar_positions": 259, "identity": "39.48%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100304-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7LGA3-1", "uniprot_id": "HS2ST_HUMAN", "id": "Q7LGA3-1", "name": "Heparan sulfate 2-O-sulfotransferase 1", "aln": "MGLLRIMMPPKLQLLAVVAFAVAMLFLENQIQKLEESRSKLERAIARHEVREIEQRHTMDGPRQDATLDEEEDMVIIYNRVPKTASTSFTNIAYDLCAKNKYHVLHINTTKNNPVMSLQDQVRFVKNITSWKEMKPGFYHGHVSYLDFAKFGVKKKPIYINVIRDPIERLVSYYYFLRFGDDYRPGLRRRKQGDKKTFDECVAEGGSDCAPEKLWLQIPFFCGHSSECWNVGSRWAMDQAKYNLINEYFLVGVTEELEDFIMLLEAALPRFFRGATELYRTGKKSHLRKTTEKKLPTKQTIAKLQQSDIWKMENEFYEFALEQFQFIRAHAVREKDGDLYILAQNFFYEKIYPKSN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R3H7-1", "uniprot_id": "HS2ST_MOUSE", "id": "Q8R3H7-1", "name": "Heparan sulfate 2-O-sulfotransferase 1", "aln": "MGLLRIMMPPKLQLLAVVAFAVAMLFLENQIQKLEESRAKLERAIARHEVREIEQRHTMDGPRQDATLDEEEDIIIIYNRVPKTASTSFTNIAYDLCAKNRYHVLHINTTKNNPVMSLQDQVRFVKNITTWNEMKPGFYHGHISYLDFAKFGVKKKPIYINVIRDPIERLVSYYYFLRFGDDYRPGLRRRKQGDKKTFDECVAEGGSDCAPEKLWLQIPFFCGHSSECWNVGSRWAMDQAKSNLINEYFLVGVTEELEDFIMLLEAALPRFFRGATDLYRTGKKSHLRKTTEKKLPTKQTIAKLQQSDIWKMENEFYEFALEQFQFIRAHAVREKDGDLYILAQNFFYEKIYPKSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QLG4-1", "uniprot_id": "F1QLG4_DANRE", "id": "F1QLG4-1", "name": "Heparan sulfate 2-O-sulfotransferase 1", "aln": "MGLLRIMMPPKFQLLAVMAFGVAMLFIENQIQKLDESRAKLERTMARHEVREVEQRQMRDGLRETPLLPEIEDLIIIYNRVPKTASTSFTNIAYDLCGKNRFHVLHINTTKNNPVMSLQDQMRFVRNVTSWREMKPGFYHGHVSYLDFTKFGVKGKPVYINIVRDPIERLVSYYYFLRFGDDYRPGLRRRKQGDKKTFDECVSSGGSDCAPEKLWLQIPFFCGHYSECWNVGSKWALEQAKYNLVNEYLLVGVTEELEDFIMMLEAALPRFFRGATELYRTGKKSHLRKTSEKKPPTKESISKLQQSNIWKMENEFYEFALEQFQFVRAHSVREKDGELYLLSQNFFYEKIYPKVN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***********:*****:**.*****:*******:***:****::*******:***: ** *: . * * **::**********************.**::*******************:***:*:*:*.**********:*****:***** **:***::***************************************:.******************** ********:**::*** **:***:*************:*************:*************:*** ***::*:*****:******************:***:******:**:*:*********** *", "identical_positions": 298, "similar_positions": 46, "identity": "83.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100308-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q00961-1", "uniprot_id": "NMDE3_RAT", "id": "Q00961-1", "name": "Glutamate receptor ionotropic, NMDA 2C", "aln": "-------------------------------------------------------MGGALGPALLLTSLLGAWARLGA---------GQ---GEQAVTVAVVFGSSGPLQTQAR-------------------TRLTSQNFLDLPLEIQPLTVGVNNTNPSSILTQICGLLGAARVHGIVFEDNVD----TEAVAQLLDFVSSQTHVPILSISGGSAVVLTPKEPGSAFLQLGVSLEQQLQVLFKVLEEYDWSAFAVITSLHPGHALFLEGVRAVADASYLSWRLLDVLTLELGPGGPRARTQRLLRQVDAPVLVAYCSREEAEVLFAEAAQAGLVGPGHVWLVPNLALG-STDAPPAAFPVGLISVVTESWRLSLRQKVRDGVAILALGAHSYRRQYG----TLPAPAGDCRSHPGPVSPAREAFYRHLLNVTWE----GRDFSFSPGGYLVRPTMVVIALN-----RHRLWEMVG---RWDHGVLYMKYPVWP-RYSTSLQPVVDSRHLTVATLEERPFVIVESPDPGTGGCVPN-TVPCRRQSNHTFSS-GDLTPYTK-----LCCKGFCIDILKKLAKVVKFSYDLYLVTNGKHGKRVRGVWNGMIGEVYYKRADMAIGSLTINEERSEIIDFSVPFVETGISVMVSRSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAITVFMFEYFSPVSYNQNLTKGKKPGGPS-FTIGKSVWLLWALVFNNSVPIENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQRPQDQYPPFRFGTVPNGSTERNIRSNYRDMHTHMVKFNQRSVEDALTSLKMGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDSHWKRAIDLALLQLLGDGETQKLETVWLSGICQNEKNEVMSS-KLDIDNMAGVFYMLLVAMGLALLVFAWEHLVYWKLRHSVPNSSQLDFLLAFSRGIYSCFNGVQSLPSPARPPSPDLTADSAQANVLKMLQAARDMVNTADVSSSLDRATRTIENWGNN-----------------------------------RRVPAPTAS-GPRSS------TPGPPGQPSPSGWGPPGGGR--------------TPLARRAPQPPARPATCG-PPLPDVS----RPSCRHASDARWPVRVGHQGPHVSASERRALPERSLLPAHCHYSSFPR----AERSGRPYLPLFPEP---------PEPDDLPLLGPEQLARREAMLRAAWAR------GPRPRHAS---------LPSSVAEAFTRSNPLPARCTGHACACPCPQSRPSCRHLAQAQSLRLPSYPEACVEGVPAGVAT-WQPRQHVCLHAHTRLPFCWGTVCRHPPPCTSHSPWLIGTWEPPAHRVRTLG---LGTGYRDSGVLEEVSREACGTQGFPRSCTWRRVSSLESEV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01098-1", "uniprot_id": "NMDE3_MOUSE", "id": "Q01098-1", "name": "Glutamate receptor ionotropic, NMDA 2C", "aln": "-------------------------------------------------------MGGALGPALLLTSLLGAWAGLGA---------GQ---GEQAVTVAVVFGSSGPLQAQAR-------------------TRLTPQNFLDLPLEIQPLTIGVNNTNPSSILTQICGLLGAARVHGIVFEDNVD----TEAVAQLLDFVSSQTHVPILSISGGSAVVLTPKEPGSAFLQLGVSLEQQLQVLFKVLEEYDWSAFAVITSLHPGHALFLEGVRAVADASYLSWRLLDVLTLELGPGGPRARTQRLLRQVDAPVLVAYCSREEAEVLFAEAAQAGLVGPGHVWLVPNLALG-STDAPPAAFPVGLISVVTESWRLSLRQKVRDGVAILALGAHSYRRQYG----TLPAPAGDCRSHPGPVSPAREAFYRHLLNVTWE----GRDFSFSPGGYLVQPTMVVIALN-----RHRLWEMVG---RWDHGVLYMKYPVWP-RYSTSLQPVVDSRHLTVATLEERPFVIVESPDPGTGGCVPN-TVPCRRQSNHTFSS-GDITPYTK-----LCCKGFCIDILKKLAKVVKFSYDLYLVTNGKHGKRVRGVWNGMIGEVYYKRADMAIGSLTINEERSEIIDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAITVFMFEYFSPVSYNQNLTKGKKSGGPS-FTIGKSVWLLWALVFNNSVPIENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQRPQDQYPPFRFGTVPNGSTERNIRSNYRDMHTHMVKFNQRSVEDALTSLKMGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDSHWKRAIDLALLQFLGDGETQKLETVWLSGICHNEKNEVMSS-KLDIDNMAGVFYMLLVAMGLALLVFAWEHLVYWKLRHSVPSSSQLDFLLAFSRGIYSCFNGVQSLPSPARPPSPDLTAGSAQANVLKMLQAARDMVSTADVSGSLDRATRTIENWGNN-----------------------------------RRAPAPTTS-GPRSC------TPGPPGQPSPSGWRPPGGGR--------------TPLARRAPQPPARPATCAGSPQPDVS----RASCRHAWDARWPVRVGHQGSHLSASERRALPERSLLHAHCHYSSFPR----AERSGRPFLPLFPEP---------PEPDDLPLLGPEQLARREALLRAAWAR------GPRPRHAS---------LPSSVAEAFTRSNPLPARCTGHACACPCPQSRPSCRHVAQTQSLRLPSYREACVEGVPAGVAATWQPRQHVCLHTHTHLPFCWGTVCRHPPPCSSHSPWLIGTWEPPSHRGRTLG---LGTGYRDSGVLEEVSREACGTQGFPRSCTWRRISSLESEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14957-1", "uniprot_id": "NMDE3_HUMAN", "id": "Q14957-1", "name": "Glutamate receptor ionotropic, NMDA 2C", "aln": "-------------------------------------------------------MGGALGPALLLTSLFGAWAGLGP---------GQ---GEQGMTVAVVFSSSGPPQAQFR-------------------ARLTPQSFLDLPLEIQPLTVGVNTTNPSSLLTQICGLLGAAHVHGIVFEDNVD----TEAVAQILDFISSQTHVPILSISGGSAVVLTPKEPGSAFLQLGVSLEQQLQVLFKVLEEYDWSAFAVITSLHPGHALFLEGVRAVADASHVSWRLLDVVTLELGPGGPRARTQRLLRQLDAPVFVAYCSREEAEVLFAEAAQAGLVGPGHVWLVPNLALG-STDAPPATFPVGLISVVTESWRLSLRQKVRDGVAILALGAHSYWRQHG----TLPAPAGDCRVHPGPVSPAREAFYRHLLNVTWE----GRDFSFSPGGYLVQPTMVVIALN-----RHRLWEMVG---RWEHGVLYMKYPVWP-RYSASLQPVVDSRHLTVATLEERPFVIVESPDPGTGGCVPN-TVPCRRQSNHTFSS-GDVAPYTK-----LCCKGFCIDILKKLARVVKFSYDLYLVTNGKHGKRVRGVWNGMIGEVYYKRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAITVFMFEYFSPVSYNQNLTRGKKSGGPA-FTIGKSVWLLWALVFNNSVPIENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQRPQDQYPPFRFGTVPNGSTERNIRSNYRDMHTHMVKFNQRSVEDALTSLKMGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDSHWKRAIDLALLQFLGDGETQKLETVWLSGICQNEKNEVMSS-KLDIDNMAGVFYMLLVAMGLALLVFAWEHLVYWKLRHSVPNSSQLDFLLAFSRGIYSCFSGVQSLASPPRQASPDLTASSAQASVLKMLQAARDMVTTAGVSSSLDRATRTIENWGGG-----------------------------------RRAPPPSPCPTPRSGPSPCLPTPDPPPEPSPTGWGPPDGGR--------------AALVRRAPQPPGRPPTPG-PPLSDVS----RVSRRPAWEARWPVRTGHCGRHLSASER------PLSPARCHYSSFPR----ADRSGRPFLPLFP------------ELEDLPLLGPEQLARREALLHAAWAR------GSRPRHAS---------LPSSVAEAFARPSSLPAGCTGPACAR--PDGHSACRRLAQAQSMCLPIYREACQEGEQAGAPA-WQHRQHVCLHAHAHLPFCWGAVCPHLPPCASHGSWLSGAWGPLGHRGRTLG---LGTGYRDSGGLDEISRVARGTQGFPGPCTWRRISSLESEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B7K5-1", "uniprot_id": "A0A8M3B7K5_DANRE", "id": "A0A8M3B7K5-1", "name": "Glutamate receptor", "aln": "----------------------------------------------------MATPRGCLGPSLQLLFFFHLLLNVVPR------CRGRPFFGPPSVNVAVVFSGS-AHHSEIK-------------------GRLSPENFLDMPLEVNPITVLVNDTNPRALLTRLCQTMAAESLHGVVFEDDVD----SEAVAQILDFVSSQTSIPIVGISGGSAVVIPHKADGSTFLQMGASIDQQINAMFKVMEEYNWGNFVVITSLYPGYETFVDYIRSFTDTSYFLWELQDVLSFEMSVGANDIRTRRLLQQVDSQVYLVYCSHEEAQYLFRMASDVGLLGPGYIWIVPSLAVGNPEAAPPASFPVGVISIITDRWRKTLRQRVREGVAIIVKGVHSFHKHRG----FIPEGHSDCSSP--VKSYANNSLFRHMLNVSWE----HKDLSFNSDGYLTNPSMVIIALD-----RENHWDKVG---SYEGGILQMRYPVWP-RYGSFLEPVSDNRHLTVATLEERPFVIVESVDPATGTCVRN-TVPCRRQSNRTESIIGHTEPYTK-----LCCKGFCIDILKKLSRTIKFSYDLYLVTNGKHGKMVRGVWNGMIGEVFYKRADMAIGSLTINEERSEIVDFSVPFVETGISVMVARSNGTVSPSAFLEPYSPAVWVMMFVMCLTVVAVTVFVFEYFSPVGYNRSLVSAKAPGGPT-FTIGKSVWLLWGIVFNNSVPIENPKGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTVSGLSDKKFQKPQEHYPPFRFGTVPNGSTERNIRSNYPDMHTHMIKYNQKGVEEALNSLKTGKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIALQKDSRWKRPIDLALLQFLGDGDTQRLETVWLSGICQNEKNEVMSS-KLDIDNMAGVFYMLLVAMGLSLLVFAWEHLLYWKLRHSVHKSDRLDFLLAISRGIYSCFNGVEDIGRSTGIQNPDITANYAQANMLKMLQTAKDIVSSAKVENSLDNATKTIENWSRRSGSLPARIPLVTTTEKVPGHFSYIANVAENHIPHMQRSITPPFTQHTTTTSPPLMVNHRVLTRPTPLRYTLPARTRGLYDGMLPVSSLSTPHLAMHDPPSDLAHTGSSFVPYRDIYTEHHKSCHNDFSDAVRRKKRPQNLLVESMDLRGLHDYKDQLTCHSEANSFPENHLSSSFSENPFVVADAACNSCAKTYFDPAFDEIPLIGKRKLHRRPSFLKATWGPDRVKFPGDRPTAAPPSRVTIPDLFPCVDVHGRVRNTMCYAQPMDHTYLHAFRRNSRKSQKLRHSQSTRLPSYKEAIFHNVAAVRRA----------SSLVHRPYSYPELPVYQSPLSYGPAELCNIFPCMGHPSDSVYGGYRAPAQLQDGHLVPVPGSRVVHSSPIVPMTWGRISSLESEV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W581-1", "uniprot_id": "Q9W581_DROME", "id": "Q9W581-1", "name": "", "aln": "MMPSRVKLKRGTDGPTPTPTPMPTTMRKHTPIATLNTASCQHNSTTSRRKRILTPPSGPISLLLLTVLTLLILDTRSCQGLRLTNGGGSLSKGAAANKEQLNIGLIAPHTNFGKREYLRSINNAVTGLTKTRGAKLTFLKDYSFEQKNIHFDMMSLTPSPTAILSTLCKEFLRVNVSAILYMMNNEQFGHSTASAQYFLQLAGYLGIPVISWNADNSGLERRASQSTLQLQLAPSIEHQSAAMLSILERYKWHQFSVVTSQIAGHDDFVQAVRERVAEMQEHFKFTILNSIVVT----RTSDLMELVNSEARVMLLYATQTEAITILRAAEEMKLTGENYVWVVSQSVIE--KKDAHSQFPVGMLGVHFDTSSAALMNEISNAIKIYSYGVEAYLTDPANRDRRLTTQSLSCEDEGRGRWDNGEIFFKYLRNVSIEGDLNKPNIEFTADGDLRSAELKIMNLRPSANNKNLVWEEIGVWKSWETQKLDIRDIAWPGNSHAPPQGVPEKFHLKITFLEEAPYINLSPADPVSGKCLMDRGVLCRVAADHEMAADIDVGQAHRNESFYQCCSGFCIDLLEKFAEELGFTYELVRVEDGKWGTLENGKWNGLIADLVNRKTDMVLTSLMINTEREAVVDFSEPFMETGIAIVVAKRTGIISPTAFLEPFDTASWMLVGIVAIQAATFMIFLFEWLSPSGYDMKLYLQNTNVTPYRFSLFRTYWLVWAVLFQAAVHVDSPRGFTSRFMTNVWALFAVVFLAIYTANLAAFMITREEFHEFSGLNDSRLVHPFSHKPSFKFGTIPYSHTDSTIHKYFNVMHNYMRQYNKTSVADGVAAVLNGNLDSFIYDGTVLDYLVAQDEDCRLMTVGS--WYAMTGYGLAFSRNSKYVQMFNKRLLEFRANGDLERLRRYWMTGTCRPGKQEHKSSDPLALEQFLSAFLLLMAGILLAALLLLLEHVYFKYIRKRLAKKDGGHCCALISLSMGKSLTFRGAVFEATEILKKHRCNDPICDTHLWKVKHELDMS-----RLRVRQLEKVMDKHGIK------------------------------------------------------------------------------------------------APQLRLASSS------------------------------------------------------------------------------------------------DLLNHHHLKERPPLLG-------------------------------------------------------------NLSLAASAQDLYRWSYKTEIAEMETVL--------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. * : * * . . : :. . : :*: . .: : : : ..* ::*: :* : : .::: : : : * ** : ::. :*::. ....: : .: **:. *:::* .::.::*.*.* * *:** .*: *:: :* . :.: : :: : * : :: * : *.:: ** :: * : * * .::*:*.. .: . : ****::.: : :* :.: :.: * *..:: . . :. .* : ::::: **: * ::.*...* * . : :: * :. *: :* :: * :: .** . : : * :. **.:: *** *:: :.. ** :* *: : * ** ::: : . : **.*****:*:*::. : *:*:* * :** *. .* ***:*.:: :::**.: ** ** **. ::*** **:****:::*:: .* :**:*****:..* *::: ::.: ..:. :*:**::** .*: .* : * *:: :: **:*.::*: :* ::.*:* **::*. ***:***:*** ********** .: :. .***.*.:: :* .: *.*:***:* . *: .*:. : **.:* ::*: .* :.: :: *:**:****.:**:*:..:**.*:*:*:** :* ****:*:.::*:: : :: **:: .:*: ::*. *::* *: *:* ** * :::: ..* :*:..: *: *:: **: : :*: : ... . :* .: ..:. : .. . . . . * :: *: : . :.::: . * . *:. .:* .* .:* :*. * . . ", "identical_positions": 228, "similar_positions": 367, "identity": "15.76%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100308-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NPA2-1", "uniprot_id": "MMP25_HUMAN", "id": "Q9NPA2-1", "name": "Matrix metalloproteinase-25", "aln": "-----------------------------------------------------MRLR-LRLLALLLLLLAP--PARAPKPSAQDVSLGVDWLTRYGYLPPPHPAQAQLQSPEKLRDAIKVMQRFAGLPETGRMDPGTVATMRKPRCSLPDVLGVAGLVRRRRR--YALSGSVWKKRTLTWRVRSFPQSSQ-LSQETVRVLMSYALMAWGMESGLTFHEVDSPQGQEPDILIDFARAFHQDSYPFDGLGGTLAHAFFPGEHPISGDTHFDDEETWTFGSKDGEGTDLFAVAVHEFGHALGLGHSSAPNSIMRPFYQGPVGDPDKYRLSQDDRDGLQQLYGKAPQTPYDKPTRKPLAPPPQPPASPTHSPSFP---IPDRCEGNFDAIANIRGETFFFKGPWFWRLQPSGQLVSPRPARLHRFWEGLPAQVRVVQAAYARHRDGRILLFSGPQFWVFQ-DRQLEGGARPLTELGLPPGE-----EVDAVFSWPQNGKTYLVRGRQYWRYD---EAAAR-PDPGYPRDLSLWEGAPPSPDDVTVSNAGDTYFFKGAHYWRFPKNSIKTEPDAPQPMGPNWLDCPAPSSGPRAPRPPKATPVSETCDCQCELNQAAGRWPAPIPLLLLPLLVGGVASR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3U435-1", "uniprot_id": "MMP25_MOUSE", "id": "Q3U435-1", "name": "Matrix metalloproteinase-25", "aln": "MCFPGSQISPARLYYLVSAPWICTGSLTSSRLPRRRESGPLRVPPRSVQAERILRLP-AFGLPLLALLLVPLLPVRAQNPDAKVVSMGVEWLTRYGYLPPADPVHAQMQSLEKLQDAIKVMQRFAGLPETGQMDPMTIKTMRKPRCSLPDVLGAAGLVRRRRR--YSLSGSVWKKRTLTWSIRSFSQKSQ-LSPQIVRTLLSYALAVWATESGLTFQEVNS-QYQEPDIIIHFARAYHQDSYPFDGSGGTLAHAFFPGEHPISGDTHFDDEETWTFGSTDDNGIDLFAVAVHEFGHALGLGHSSAPNSIMRPFYQGPVGDPATYRLPQDDRDGLQQLYGRVSQNPNARPTRKPLVPPPQPPAMPPDSPATP---VPDRCEGNFDAVANIRGEIFLFKGPWFWRLQPSGQLVSPRPAGLHRFWEGLPTHVKVIQAAYARPLDGRIILFSGPQFWVFQ-ERQLEGAARPLVEFGLPPGE-----DVDAVFSWPHNGKTYLIRGQKYWRYD---EVAAR-PDPGYPRALSLWDGAPFAPDDVTISNTGDTYFFKGTHFWRFAEGSVKAESDSPQPIGPKWLDCPAPNSDPRVTSPPKTTSKTRSCDCHCELNQAS-EQLSPLLLPLLPLVAGEVFSY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F1N5-1", "uniprot_id": "E7F1N5_DANRE", "id": "E7F1N5-1", "name": "", "aln": "-----------------------------------------------------MSFSGYLGLVYLTCPMLVFFSAVHSAPVKDQYSRGVDWLSRYGYLPPLDPRTGQLQSKDGIERAIREMQRFAGLKETGKLDSDTLTLMNTPRCSLPDIIGIEDKLKKRRRKRYATTGLRWTKSDITWSVQNYPSVHKRLTPTQVDPIISYALKAWSDVTNLNFYGASSSEKDRADIRISFARSLHDDGYPFDGKGGTLAHAFFPGESDVAGDTHFDDDEIWTY--LDESGTDLFAVAVHEFGHALGLSHSSSSPSIMKPYYQGSVGDVGSYILPDDDREAIQSLYGRKISSPTPSPN-KPTSHLPKPPATYPKGPVKPDPSIQNRCEGGFDAVANLRGEVFFFKGPYFWRIQRTGSLVSFQPAHIKNFWMGLPPTTNKVDAVYERKVDNAIIFFIGSQYWVFKNTEVLPGYPRPLSDWGMITQDGRKVMRVDAAFIWAHNGKTYIFSGGEFWRFSEGRETELRGPDTGYPRNTNLWKGAPSNPDDVITWGQGDAYFFKDNSYWVLKNGEMDQTSVTKKSTAVDWMMCQQET-----TKAPESPRRREGVNCYCDNSAGLQMSVSAWLLLITALLHIGFNSQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * * : .. * . * **:**:******* .* .*:** : :. **: ******* ***::*. *: *..*******::* . :::*** *: :* *.* :** ::.:.. : *: * ::**** .*. :.*.* ..* : :..** * ***: *:*.***** ************ ::*******:* **: * .* ****************.***:. ***:*:***.*** .* *.:***:.:*.***: ..* *. ** *:*** ...* * : :****.***:**:*** *:****:***:* :*.*** :** ::.** ***. .. ::*.* * *. *::* *.*:***: . * * .*** : *: . : ***.* *.:*****:. * ::**:. *. * **.**** .**.*** **** . **:****. :* : :..:. . : :. . .*: * . . .*::. . :* *: . . :. * : .*: . * ", "identical_positions": 240, "similar_positions": 160, "identity": "37.85%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100309-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N0W4-1", "uniprot_id": "NLGNX_HUMAN", "id": "Q8N0W4-1", "name": "Neuroligin-4, X-linked", "aln": "---------------------------------------------------------------------------------MSRPQGLLWLPLLFTPVCVMLNSNVLLWLTALAIKFTLIDSQAQ------------------------------------------YPVVNTNYGKIRGLRTPLPN-EILGPVEQYLGVPYASPPTGERRFQPPEPPSSWTGIRNTTQFAAVCPQHLD---ERSLLHDMLPIWFTANLDTLMTYVQDQNEDCLYLNIYVPTED------------------DIHDQ-------------------NSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTG----DQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLT--LSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLD------------TTDMVECLRNKNYKELIQQTITPATYHIAFGPVIDGDVIPDD------PQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDG-----------------------------VTPNDFDFSVSNFVDNLYGYPEGK-----------------DTLRETIKFMYTDWAD-KENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSP-----------------------------TYFYAFYHHCQS----------------------EMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPN-RFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLN------------------------EIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPAN-------NPKHSKDP-----------------------------------HKTG--PEDTTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRR-PSPQRN----------------------------------------------------------------------TTNDIAHIQ--------------------NEEIMSLQMKQ----LEHDHECES------------------------------------------------------------------------------------------------------------------------------LQAHDTLRLTCPPDYTLTLRRSPDDIP-----------------------------------LMTPNTITMIPNTLTG--MQPLHTFNTFSG---------------------------------------------GQNSTNLPHGHSTTRV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8NFZ3-1", "uniprot_id": "NLGNY_HUMAN", "id": "Q8NFZ3-1", "name": "Neuroligin-4, Y-linked", "aln": "---------------------------------------------------------------------------------MLRPQGLLWLPLLFTSVCVMLNSNVLLWITALAIKFTLIDSQAQ------------------------------------------YPVVNTNYGKIQGLRTPLPS-EILGPVEQYLGVPYASPPTGERRFQPPESPSSWTGIRNATQFSAVCPQHLD---ERFLLHDMLPIWFTTSLDTLMTYVQDQNEDCLYLNIYVPMED------------------DIHEQ-------------------NSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTG----DQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLT--LSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLD------------TTDMVECLKNKNYKELIQQTITPATYHIAFGPVIDGDVIPDD------PQILMEQGEFLNYDIMLGVNQGEGLKFVDGIVDNEDG-----------------------------VTPNDFDFSVSNFVDNLYGYPEGK-----------------DTLRETIKFMYTDWAD-KENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSP-----------------------------TYFYAFYHHCQS----------------------EMKPSWADSAHGDEVPYVFGIPMIGPTELFSCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPN-RFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNLN------------------------EIFQYVSTTTKVPPPDMTSFPYGTRRSPAKIWPTTKRPAITPAN-------NPKHSKDP-----------------------------------HKTG--PEDTTVLIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHETHRH-PSPQRN----------------------------------------------------------------------TTNDITHIQ--------------------NEEIMSLQMKQ----LEHDHECES------------------------------------------------------------------------------------------------------------------------------LQAHDTLRLTCPPDYTLTLRRSPDDIP-----------------------------------FMTPNTITMIPNTLMG--MQPLHTFKTFSG---------------------------------------------GQNSTNLPHGHSTTRV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QBU0-1", "uniprot_id": "A0A8M9QBU0_DANRE", "id": "A0A8M9QBU0-1", "name": "", "aln": "---------------------------------------------------------------------------------MSRLRGTPWIPLTMVHPLATLR---LFTWIVLAAAWLAITWAQQ------------------------------------------HPIVTTNYGKLRGLKTPLPN-EILGPVEQYLGIPYALPPTGERRFQPPEPPMSWPGIRNATQFAPVCPQFLE---DRFLLNDMLPVWFTANLDTVVTYVQDQSEDCLYLNIYVPTEDVGANKGDDFTNNEGGENKDIHDE-------------------NGLRPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVVTLNYRLGVLGFLSTG----DQAAKGNYGLLDQIQALRWIKENIQAFKGDPKRVTIFGSGAGASCVSLLT--LSHYSEDLFQKAIIQSGTALSSWAVNYQPAKYTRILAEKVGCNMLD------------SIDLVECLQNKNYKELIEQYITQAKYHIAFGPVIDGDVIPDD------PQILMEQGEFLNYDIMLGVNQGEGFKFVDGIVDSEDG-----------------------------VSANDFDFAVSDFVDHLYGYPEGK-----------------DTLRETIKFMYTDWAD-KENPETRRKTLVALFTDHQWVAPAVATADLHAQYGSP-----------------------------TYFYAFYHHCQS----------------------EMKPSWSDSAHGDEVPYVFGIPMLGPTDLFNCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPN-RFEEVAWSKYNPKDQLYLHIGLKPRVRDHYRATKVAFWLELVPHLHNIN------------------------ELFQYVSTTTKIPPQDTTPFPYTKRLG--KTWPSTTRHPGVPPA-------NTKQTTDQ-----------------------------------RKGNDLSDDSAVVIETKRDYSTELSVTIAVGASLLFLNILAFAALYYKKDKRRHESNRRGPSPQRNS--------------------------------------------------------------APANVVANANDIAHLQ--------------------SDELMSLQMKQQQMEHEHHHECDS------------------------------------------------------------------------------------------------------------------------------LQAHDTLRLTCPADYTLTLRRSPDDIP-----------------------------------LMTPSTITMIPNTLAG--MQTLHNFNTFGG---------------------------------------------SQNSTNLPHGHSTTRV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B0F2B4-1", "uniprot_id": "NLGN4_MOUSE", "id": "B0F2B4-1", "name": "Neuroligin 4-like", "aln": "---------------------------------------------------------------------------------MPAP-----VPALLCLA------------LALASAQPSPPPPPP------------------------------------------FPVVATNYGKLRGVRAALPG-DVLGPVTQFLGVPYAAPPTGERRFQPPEPPSSWAGVRDATRFAPVCPQHLD---ERALLRDCLPAWFAANLDAIAAYVQDQSEDCLYLNLYVPGGANGKKMADDVTGNDHGDDQDSRDPGVGGAAAA-----------AARKPVMVYIHGGSYMEGTANIVDGSVLASYGDVIVVTVNYRLGVLGFLSTG----DQAAKGNYGLLDQIQALRWVEENAGAFGGDPDRVTVFGSGAGASCVSLLT--LSHYSEGLFQKAIIQSGTALSSWAVNYQPARYARALGERVGCATPDPGSPPGSPPGWDSASLVSCLRGKAAGELARARVTPATYHVAFGPTVDGDVIPDD------PQILMEQGEFLNYDIMLGVNQGEGARFVDGLGGGHDGGYGGYGGGYGGGVEDDEVQDGGPDGAAGGVSAGEFDLAVSGFINDLYGRPEGRG----------------DALRETVKFMYTDWAD-RDSPEARRKTLVALFTDHQWVAPAVATADLHARYGSP-----------------------------TYFYAFYHRCHGGGGGGGGVDGVAGGVAGGVGGEEARPAWADAAHGDEVPYVFGVHMAGPGDVFGCNFSRNDVMLSAVVMTYWTNFAKTGDPNQPVAQDTRFVHTRPN-RFEEVAWAKYDPRGQLYLHIGLRPRVRDHYRAAKVAFWLELVPHLHGLAAD---------------------PGAYLSAAATRAAPSGDPDRDPGGGGGGRRRPRPATRRPAVMTSSSMASGSGMTSSSGSG-----------------------------------MTSSSGSSASAVLIETRRDYSTELSVTIAVGASLLFLNVLAFAALYYKKDKRRHETHRR-PPPPRPP--------------------------------------------------------------QAPPSAAAADRNPRPDPGPAG---------RRGGECGAVVTAMAAEASAGGLGHDGVGGVGV-------------------------------------------------------------------------------------------------------------------------GGVIGGVAGLRLACPPDYALTLRRSPDDVPRA---------------------------------GAGPGTMTLIPGALGGGGGGAVHGFNTFGSGVGVAGVAGVAT---------------------------------SQAGPGLPHGHSTTRV----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VIC6-1", "uniprot_id": "Q9VIC6_DROME", "id": "Q9VIC6-1", "name": "", "aln": "-------------MVMLLSKRQLPPSAATRTRRKVPPTRRRSTWALSSLLALVVLDICIARCLAAGISYSSNSGNLSTSQKSPSSANNGGLVLIGSSSATSSSVPSLSLTSSSSAGLSSPGSSSSSSSSSTSTSGSNSNRSSRPTSNNSNSNSNYSPNHDQLPAQLSSRIINTRNGAISGVIVQLDG-RHLDPVEAYRGIPYASPPVGNLRFMPPVSAAMWSGVKKADRFSPVCPQRLPDIHNETAALERMPKGRLEYLKRLLPYLQNQSEDCLYLNIYVPIQVGSRDSSGSSSSSSAGSSSSGSGGSSSSSSSSSTSSSSAGSGSPAKYPVLVFVHGESYEWNSGNPYDGSVLASYGQILVVTINYRLGVLGFLNANTDRYS-KLPANYGLMDIIAALHWLKENIAAFGGDPNSITLAGHGTGAACVHFLISSMAVPEGLLFNRAILMSGSGLAPWSLVSNPAKYAAIVAHHVNCAS-----------DLPHAHLMKCLREKTLDQLLSVPIRPPEFGFAFGPSIDGVVIDGG-------DYVPPAPGSPAAQAQAQASTAAGNGLGGEAGIAAAGGWGTPGQLENIVLMRKTAINKLSRYDLMAGVTRAEAFFSFNSGDVQYGIEADRRSRILKAYVRNTYTFHLNEIFATIVNEYTDWERPVQHPINIRDETLEALSDAQVVAPAAQTVDLHSADHR-----------------------------NSYLYVFDYQTRF----------------------GDYPQRQGCIHGEDLPYIFGAPLVGGFNHFTRNYTKTEISLSEVVMFYWSNFVRTGNPNEQMETEHGS--RQERSRYKTIEWTAYESVHKKYLNFDTKPKLKNHYRAHRLSFWLNLIPDLHKPGGDNVPAAHHQLHDDDD------EDNNIPSDASVKPLNPPYISRAANAAAMANFTIFTNQVFSLLNLSSPSSSLQRNGTRYGGG-----KIYPDDMMD------GDHAGG--------AASASQD-------SDGFAAYSTALSVTIAIGCSLLILNVLIFAGVYYQRDKTRLSEPRPQTKLKRQ--------------------ENGQMPNNICGDLETLTIHA---------------------KSDPATILSHHHAMQHHQLP------------------PPEFADIPHRAPPPPKHMKSLQDP------------------------------GGGGSVSG--AVGVSG--------VVQMPPP---------------HALQVMGNQCGTLTKKS------------------------------CMKQTQ----AQAQQHSPAQQQQQQQQQQQQ-------HVVT--HQQHLQN---------------HHNQSMTTVLTTAGG-----LVVPTPP------TVPVIVASTTQHQQH--------------------------QQQHQQQQHQQQQQQQQQQHPLMDELRV----------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A6H2EDS1-1", "uniprot_id": "A0A6H2EDS1_DROME", "id": "A0A6H2EDS1-1", "name": "", "aln": "---------------------------------------------------------------------------MGESQ----------LLLLLR---------LLLLPTVLISWMHCAGASTADIYKG---------------------------------ARLGHRIVQTRYGRLHGLILPLDSFRFLRSVEVFLGVPYATPPTKQNRFSPTRAPAPWDGIRISDKYSPVCPQRLPNIQNETAALEKMPKGRLEYLKRLLPFLENQSEDCLYLNVFSPVNAGANEK---------------------------------------KLPVIVFIHGESFEWSSGNPYDGSVLASYGEVVVVTLNYRLGILGFLNANPNPHAHARVANYGLMDQMAALHWIQQNIQKFGGDPNSVTLAGHGTGAACINYLMTSPTMVRG-LFHRAILMSGSAYSSWALVEDPVLFAIKLAKEVNCTIPDD-------INRHHEQIVDCLRDVPLEDLYLADIQAPNFLTSFGPSVDGVVIRPGHSNLDIDDLMARNSRRSSADSGFQSSAGGGGGQGGGAGGGGGGGSGSSFGGGYFGGSGAGTMNMGGHYDVLFGVVTGESIWRFSAHDIQNGFEGERRDKIIRTYVRNAYNYHLNEIFYTIVNEYTDWDRTSQHPINTRDTAVAALSDAQFVAPIVRAGDILAANSPPPVSSSSTAGSPGANAAASTSAGSTQPSGRCYFYVFDYQTKD----------------------GDYPQRMGTVHGEDLPYIFGAPLVDGFSHFPQNYTKSETALSEAVMIFWTNFARTGNPNEHHRQDSSLPVSKERNRFRSITWENYDPLHQKYLEIGMKPRIKNHFRAHQLSIWLRLIPELHRAGMEDVIARHNLFRNHDD------MD---LYEGPVKP-DPFGISTAAGASGSSSSSSSSSRLLLVDEQLMMKKGRGLNGSAYLNGILGVTTVEPNNMYTTCIPIGGNYSSSGGVFAPTTLANASSDTLASGFEAAGYAAYSTALSVTIAIGCSLLILNVLIFAGVYYQRDKTRLEVKTLQKQYQQRSLHQQVPYPPEPIKHAHYHMGHSQSSANVIVDVESHQDQAGQAAMLLQAAAAAAAAAANDVKPPPPHICSNTGMQQQQQVGGGSGGALNNGGIEGSKVTTDNLGNVTYSTSSKQQQQHQQQQQQQQREHMQIKGMTGTQTFGRSGSGSGGGAGGGAGSASGGASVVVSGSSVSYNPGMMTLPKSGGLHHAATLNYARNTTALNMSGGGTALVDSRGNVLLTSTAVGPGMAGTGAGGGSSGGGGGGDCMTLPRNLGLAAAGRHNPTTELQQYQQQQQSSKHQSNGAVLTGMQSHHIRGPRPPLRTASSTTTNSSSNNSAMGVAVGVGGGVGNMLLDQTPSGGSSSSGVSSAPSSSKGHHTHSHSHAAHLVHSHGDGLVLTSASPVGGQQQQHPQQHQHPQQQQQVPQAAMDEMREFYAPKQPDDDGQLNGTPVDADAATQVVGAGRTGGMGAPPISASDHKQRQLKKLRFKREIHALALEGGDVARGYCSCDEQWTNSSSPTSTTTSATMSPTLPAGGSAGDAGRHATGNGPGNSSAGSSGIVKMAAAPGKRSERLKQQHHVRFSDEKNFSD---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VIC7-1", "uniprot_id": "Q9VIC7_DROME", "id": "Q9VIC7-1", "name": "", "aln": "MKFRLAAFWLFLLTVGGNHKLLSHVSPMGVAAEKQPLHKGNELENAMKLREAPKQSRVIGDITTTIQPDSDPGRSIGHQALRRAKAPPPSLELHFRQNLNKLFAGDETTHVGHTNATDNTTAAVLATDEGSS-------------EHEPSTTHHPERRHVVPDKLQYTQEIQVKQGRLMGITRRFQVTSGLRQVDQFLGLPYAEAPTGNRRFMPPGAPLPWQGLKIARHLPPVCPQKLP--DLSPHGSENMSRARHKHLSRLLPYLRTESEDCLYLNLYVPHEEPQSTP--------------------------------------KQYAVLVYLHGESFEWNSGNPYDGSVLSSYGEVIVVTVNYRLGVLGFLRPS---IDAHNIANYALLDQIAALHWIKENIEAFGGDNSRVTLMGHSTGAACVNYLM--VSPVASGLFHRAILMSGSAMSDWAASNQSLQLTMQIAHALECPLNEHVEAE------DDDVLLDCLRHRRYQDILHIPTALTQFSTSLGPIVDGHVIPNQ----PYKVMGHYTEHFSRYDLLFGITESESYHTLAALALEEGLR------------------------------ENERDNLLRFYMQSRFDIRPDLA---------------LAATLKKYQDMYNNPIK--ATNLEHRDVVLDILSDARVVGPLLQTGMFHADVNRR-----------------------------NYMYVFGHNSAT----------------------GPFAHLPHSIMGEELAFIFGAPLAAAGPFPSGNYTVQEKLLSEAVMAYWTNFVKTGNPKAPWKG-IFINSHALEWDRYDLDWPEFNRRAQAYLNIGIPPTVGYKYRQIYMNFWNKELPDELNQIAAIQEQLQKPGQEVITGHMSKYGPRDHGAEDPVRTLKLLLQEPSLAGPTQSGESTETAAENMYNAPPTFGHVHKMQGGSDFEDLVTS------------------------------TNSLESGEDHPQAPPETVAKSEATMQLLIALITIIIVLNLLIYGTFLLRQRRRRAKALPFPAPKLGGTILSYDG--ANDEELKRCSKSRDGDDSFVLEMTRKSNTYEAIKTGQRSLSCSTVDTHTKVCEWMSSQEAPKSGSFNTATPPPQPILSDGRLIICQDIEVADAALLIPQHMHEPQHYEMLLQRQHS---------------------------------ALTEPSDEILQQQYPLRNHSHSHSDPVDMILAADEQVTSFVHADDVDINVTSRDDSDG----------------------------LEVIPLTSAQQLELLRQRNYPKVLPTEQDLINSS---------------YKRNSLPPQNFNAPLPPPRTISNTLGRRRRDSSNITTSPLQVARDCGGEDEDLKEPQITQNTLIVGPIVPK-----------------SPASSLKRVKRMPESSAMTALSGSFQSFEAVPPAHETTPPQGGERTECIYAIRPSPGSCSWAAPNGDLYAQPMKSSSRNSLIPRPTKPAESQSQATPAGPAGESLGSTGMATASRIPQLQRQASGKDLQARTATDNTANPLGCQPRTDSTISSGSSASYASTTDSSSSSSTGTVRTELQQFQPAPGRSITTNI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .. * : *: : * * : *:*** .*. : ** *. .. * *:: : : ..**** * : :. *. : .::. :.*******:: * .*:*::** *: .:.* ***:*:***:::*:*:*****:**** .. .**.*:* : **:*:::* * ** . :*: * .:**:*: * : **::**: **:. : *: :. : :.. : * ::.**: :: . : ::** :** ** : . . . : . . *.: *. : ::* : *.* : : : *:*.* :. . *:::.::** : *:: : ** .** :*:**.:**:*: . : * :: : **.:. * : ::* : :* . :*. .. . . . .: :.: **: ::.**:* :. . :: : * . : . . : : . : : . ", "identical_positions": 120, "similar_positions": 180, "identity": "7.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100311-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AEI2-1", "uniprot_id": "A0A8I6AEI2_RAT", "id": "A0A8I6AEI2-1", "name": "RUN domain-containing protein 1", "aln": "--------MATVEVATELGTVVTAVGPKAKDEEEEEDEEESLPPCETVRWAPVGAVAEAGPGAATFSEEAAAE--EPGAAPGSPPDATVRTLRRLQAERRQLDSALLALSSHFAQVQFRLRQVVRGAPAEQQRLLRELEDFAFRGCPHVLGYEGLEDPCDSEESDVLPGDRPRVRGEVQGLSEQEKRERLETQREKQKELILQLKTQLDDLETFAYQEGSYDSLPQSVVLERQRVIIDELIKKLDMNLN-EDISSLSTEELRQRVDAAVAQIVNPARVKEQLVEQLKTQIRDLEMFISFIQ-----DEVGSPLQTGG-HCECKTSGKAGISSTRAGSSTLPPGPDKAKA--------EDTKWVRETGLHLMRRALAVFQIFAVSQLG--CATGQIPQTLWQRGQADRDYSPLLKRLELSVDRVKQLAL----------------RHQP-------------------------------------------HDHVITSANLQDLSLGG-----------------------RDELTMAVRKELTVAVRDLLAHGL--YASSSGMSLVMAPIACLLPAFSSAP-------------ETMHPWELFVKYYHAKNGRAYVESPARKLSQSFALPIMGD-AAVTPKQSLLTAIHLVLTEHDPFKRSADSELKALVCMALNEQRLVSWVNLICKSGSLIEPHYQPWSYMAHTGFESALNLLSRLSSLKFSLPVDLAVRQLKNIKDAF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0VDN7-1", "uniprot_id": "RUND1_MOUSE", "id": "Q0VDN7-1", "name": "RUN domain-containing protein 1", "aln": "--------MATVEVATELGTVVTAVGPKAKDEEEEEEEEESLPPCETVRWAPVGAVAEAGPGAATFSEAAAAE--EPGAAPGSPSDATVRTLRRLEAERRQLDSALLALSSHFAQVQFRLRQVVRGAPAEQQRLLRELEDFAFRGCPHVLGYEGLADPCGGDESDVLPGDRPRVRGEDQ--SEQEKRERLETQREKQKELILQLKTQLDDLETFAYQEGSYDSLPQSVVLERQRVIIDELIKKLDMNLN-EDISSLSTEELRQRVDAAVAQIVNPVRVKEQLVEQLKTQIRDLEMFISFIQ-----DEVGSPLQTGG-HCECQASGKVGIGSTRVGGSTLPPGPGKAKA--------EDAKRARETGLHLMRRALAVLQIFTVSQLG--CATGQIPQTLWQRSQADRDYSHLLKRLEVSVDRVKQLAL----------------RHQP-------------------------------------------HDHVITSANLQDLSLGG-----------------------KDELTTVVRKELTVAVRDLLAHGL--YASSSGMSLVMAPLACLLPVFSSAP-------------ETMHPWELFVKYYHAKNGRAYVESPARKLSQSFALPIMGD-TAVTPKQSLLTAIHLVLTEHDPFKRSADSELKALVCMALNEQRLVSWVNLICKSGSLIEPHYQPWSYMAHTGFESALNLLSRLSSLKFSLPVDLAVRQLKNIKDAF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96C34-1", "uniprot_id": "RUND1_HUMAN", "id": "Q96C34-1", "name": "RUN domain-containing protein 1", "aln": "--------MAAVEAAAEPVTVVAAVGPKAKDEEEEE--EEPLPPCEAVRWAPVGAVAEARPGATAFLEEATAE--EPGAAPGSPPDSPGRTLRRLRAERRRLDSALLALSSHFAQVQFRLRQVVRGAPAEQQRLLRELEDFAFRGCPHVLGYEGPGDPAS-DEGDGLPGDRPWLRGEDQ--SEQEKQERLETQREKQKELILQLKTQLDDLETFAYQEGSYDSLPQSVVLERQRVIIDELIKKLDMNLN-EDISSLSTEELRQRVDAAVAQIVNPARVKEQLVEQLKTQIRDLEMFINFIQ-----DEVGSPLQTGGGHCECKAGGKTGNGCSRTGSSRTPPGNSKTKA--------EDVKKVRETGLHLMRRALAVLQIFAVSQFG--CATGQIPPTLWQRVQADRDYSPLLKRLEVSVDRVKQLAL----------------RQQP-------------------------------------------HDHVITSANLQDLSLGG-----------------------KDELTMAVRKELTVAVRDLLAHGL--YASSPGMSLVMAPIACLLPAFSSAP-------------EAMHPWELFVKYYHAKNGRAYVESPARKLSQSFALPVTGG-TVVTPKQSLLTAIHMVLTEHDPFKRSADSELKALVCMALNEQRLVSWVNLICKSGSLIEPHYQPWSYMAHTGFESALNLLSRLSSLKFSLPVDLAVRQLKNIKDAF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I3IT29-1", "uniprot_id": "I3IT29_DANRE", "id": "I3IT29-1", "name": "RUN domain-containing protein 1", "aln": "--------MSTEDLSTSDSEAAFAG--------------------AGERWAPVGAVAN--PEDEHWKTGAQAG--SVSSGDG----EMVSRLRKMEDEQEQLNSSLLALTSHFAQVQFRLKQIVHAQSDEKERMLLELEEFAFRGCPHVVG-------CRAQDAHMLENS-----------SEREKRERLEAQRNKQKELIFQLKNQLDDLERFAYQEGSYDSLPQSVVMERQRVIIDELIKKLDVNLN-EDIGNLTPEELRQRVDAAIAQIVNPARVKEQLVEQLKTQIRDLEMFINFIQ-----DEVGNPLLNDG--TKSQPTHAAGPNTGATG------GVKRVDP--------EQAQRMRETGLQLIQKALAVLQIFALSQFG--CAAGHVPQNMWSQGAEAQDYGPLLQKLEGAVERVRLQAS----------------RHQPS----------------------------------------SLDEHVVSYS--ASLSPEGP----------------------RDELTASVRKELAIALRDLLAHGL--YAPSQGMSLVLAPISCLLP-FSSSP-------------QTLHPWELFVKYYHSKNGQAFVESPARQLSQSFSLPVGGGPVTVTPKQSLLWAIHTVLKEHRRFKRSTDSEFKALVCMALNEQRLVSWLNLLCKSGTLIHSHYQPWSYMAQTGFEGALRILGRISHLKFSLPVDLAVRQLKNIKDAF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W5C1-1", "uniprot_id": "Q9W5C1_DROME", "id": "Q9W5C1-1", "name": "RUN domain-containing protein", "aln": "MEMKMAEAQETKDSCSTIEGQLPAGPVRAEDEEEEVEVEQEQQELLSERWSPLGANYDDANSASSGVDCELEPGLEKSEARRGSTGSELARLRSIEEEQELLTSSLLALTSHFAHVQLRVRQIVEAPAEERDQLLRDLEDFAFQGIPDAVQ---------SKESHPDKPA-----------SDGEKDHGPDSQ------LIQQLKSQLTELEQIAYEAGEPGILPQHVLLEKQKFILDELRAKLNLQVEQHELPALSTEQLRHQVDNAIGEFVGPLKMKEQLVAQLKTQITDLERFIAFLQCDAIEGSVGDRLKLLSGAYNSYAAKQTARSSQASYVATNAPATTATTPPSSGLGAHSSGESLHSKAHGLLDKASVLMQMFASTHLVKPRTHDEFQQNSLKKTHKGNHWGDLRAQLEVDIQEVAALAATLSCDREKLANIKRALRKQQQQAESTEFSDTGNPVINSQNGALTLPPRCRRAVPTGHELAPYASGGAISSDSDEDISYSNFEWEKESKSRRTTHARGDSIATIGRELTTVVRKNFARTLQQLIQHGLRIPAESAASSLMVPFMRCLHPGPPVVPPAVGGDSQFLGLGRAMHAWELVLAYYRLKHGEEYNNTPARKLSQSFQLDIVDA-QAVTAKQSLLSAVGMILAMHRPYKRSNNAHFKAFVCAGLNSHLLVEWLNLILSCHELVDTYYSADSYVARTGFRDSLRSIDALSRFDFDLPVDLAIRHFRNI----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .: * **:*:** : . . . ** :. *:. * *:****:****:**:*::*:*.. . *::::* :**:***:* *..: .:.. *: ** . ::* ** ***.** :** :**: *. . *** *::*:*:.*:*** **::::: .:: *:.*:**::** *:.::*.* ::***** ****** *** ** *:* ..**. * . :. . .. . . . . .. : :... *: :* .::*:*: ::: : ... . .: ..:. * :** ::.* * *:* .:: .:* . *** ***::: ::::*: *** * * . **::. : ** * . * .::*.***.: **: *:*. : ::***:***** * : . .**.***** *: :* * :*** ::.:**:** .**.: **.*:**: .. *:..:*.. **:*:***..:*. :. :* :.*.******:*:::** ", "identical_positions": 182, "similar_positions": 196, "identity": "24.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100311-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6ACU1-1", "uniprot_id": "A0A8I6ACU1_RAT", "id": "A0A8I6ACU1-1", "name": "", "aln": "------------------------------------------------------------------------DSTTLESS--GLQEEQSRLKTRLQELQQLKRERIDA--------PRDKIPFPVPEVPVVFQGLTKQSGQAPKSLVSNLKICCPLPGGSALITFDDPKVVERLLQQKEHKVDIEDCRLRVQIQPLELPMVTNIQVSSQPDSHRVLVSGFPTGLRLSEEELLDKLEIFFGKAKNGGGDVETREMLQG--TVMLGFANEEVAQHLCQIGQFRVPLGRQQVLLRVSPYVSGEIQEAEIKFQQAPHSVLVTNIPDVLDVQELHDILEIHFQKPTRGGGEVEALAVVPVGQQGLAVFTSESS------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8C4-1", "uniprot_id": "IN35_MOUSE", "id": "Q9D8C4-1", "name": "Interferon-induced 35 kDa protein homolog", "aln": "------------------------------------------------------------------------MSVTLQTVLYSLQEEQARLKMRLQELQQLKRERTGS--------PGAKIPFSVPEVPLVFQGQTKQGRQVPKFVVSNLKVCCPLPEGSALVTFEDPKVVDRLLQQKEHRVNLEDCRLRVQVQPLELPVVTNIQVSSQPDNHRVLVSGFPAGLRLSEEELLDKLEIFFGKAKNGGGDVETREMLQG--TVMLGFADEEVAQHLCQIGQFRVPLDRQQVLLRVSPYVSGEIQKAEIKFQQAPHSVLVTNIPDVMDAQELHDILEIHFQKPTRGGGEVEALTVVPSGQQGLAIFTSESS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P80217-1", "uniprot_id": "IN35_HUMAN", "id": "P80217-1", "name": "Interferon-induced 35 kDa protein", "aln": "------------------------------------------------------------------------MSAPLDAALHALQEEQARLKMRLWDLQQLRKELGDS--------PKDKVPFSVPKIPLVFRGHTQQDPEVPKSLVSNLRIHCPLLAGSALITFDDPKVAEQVLQQKEHTINMEECRLRVQVQPLELPMVTTIQMSSQLSGRRVLVTGFPASLRLSEEELLDKLEIFFGKTRNGGGDVDVRELLPG--SVMLGFARDGVAQRLCQIGQFTVPLGGQQVPLRVSPYVNGEIQKAEIRSQPVPRSVLVLNIPDILDGPELHDVLEIHFQKPTRGGGEVEALTVVPQGQQGLAVFTSESG------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A8Q4-1", "uniprot_id": "A0AB13A8Q4_DANRE", "id": "A0AB13A8Q4-1", "name": "", "aln": "MSTEDFCELDCESLGPLDNVQMELNKCKKTYKALLNEQKILRDGIDNNKEFAKKFRERAEEQKESNENENKKRSKKIQSEKEKCRAIESHNTKQRMEILKIKEELQSLDNKNSSLKKQTEISTAVPERKVVFEGKTKNGAHATSFDVK-SQIVYPMEGGTALITFEEEDVAQNILSQQKHLVALGECGITVQAKPIQFLVPGYVEMETQVCSHRILVSNLPIEE--PEERILDKLDIHFSRKRNGGGEVEETDMLHDSKTVVITFVEDNVAKPLTDKQEHEVDFGKRKYKVKVTPFLNGKISEMKISNSVCMRTVLLTGIPDIMDKDNLQDNLEIHFQKTSNGGGEVEAIIYNPLGQTSTAVFDEDSPKDSQTE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::: : ::: . : :: :::.* . ::. .**: :**.* *::. .... *. :: *: *:**:**:: .*.:.:*.*::* : : :* : ** :*::: : :::.:* .:*:**:.:* .**.:****:*.*.: :****:*: ::* . :*:: *. : **: * : :. * :. :: ::*:*::.*:*.: :* . ::**: .***::* :*:* *******.:.*******: * ** . *:* .:* ", "identical_positions": 81, "similar_positions": 119, "identity": "21.66%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100311-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O75145-1", "uniprot_id": "LIPA3_HUMAN", "id": "O75145-1", "name": "Liprin-alpha-3", "aln": "MMCEVMPTISEDGRRGSALGP-----------------------------DEAG--GELERLMVTMLTERERLLETLREAQDGLATAQLRLRELGHEKDSLQRQLSIALPQEFAALTKELNLCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPGGVSSEVEVLKALKSLFEHHKALDEKVRERLRMALERVAVLEEELELSNQETLNLREQLSRRRSGLEEPGKDGDGQTLANGLGPGGDSNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQRDLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEKNQELQRARQREKMNDDHNKRLSETVDKLLSESNERLQLHLKERMGALEEKNSLSEEIANMKKLQDELLLNKEQLLAEMERMQMEIDQLRGRPPSSYSRSLPGSALELRYSQAP-TLPSG--AHLDPYV-AGSG---RAGKRGRWSGVKEEPSK--DWERSAPAGSIPPPFPGELDGSDEEEAEGMFGAELLSPSGQADVQTLAIMLQEQLEAINKEIKLIQEEKETTEQRAEELESRVSSSGLD-------SLGRYRS-SCSLPPSLTTSTLASPSPPSSGHSTPRLAPPSPAREGTDKANHVPKEEAGAPRGEGPAIPGDTPPPTPRSARLERMTQAL--ALQAGSLED---GGPPRGSEGTPDSLHKAPKKKSIKSSIGRLFGKKEKGRMGPPGRDSSSLAGTPSDETLATDPLGLAKLTGPGDKDRRNKRKHELLEEACRQGLPFAAWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMANLSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPASSRTSTGNVWMTHEEMESLTATTKPETKEISWEQILAYGDMNHEWVGNDWLPSLGLPQYRSYFMESLVDARMLDHLNKKELRGQLKMVDSFHRVSLHYGIMCLKRLNYDRKDLERRREESQTQIRDVMVWSNERVMGWVSGLGLKEFATNLTESGVHGALLALDETFDYSDLALLLQIPTQNAQARQLLEKEFSNLISLGTDRRLDEDSAKSFSRSPSWRKMFREKDLRGVTPDSAEMLPPNFRSAAAGALGSPGLPLRKLQPEGQTSGSSRADGVSVRTYSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60469-1", "uniprot_id": "LIPA3_MOUSE", "id": "P60469-1", "name": "Liprin-alpha-3", "aln": "MMCEVMPTISEDGRRGSALGP-----------------------------DEAG--GELERLMVTMLTERERLLETLREAQDGLATAQLRLRELGHEKDSLQRQLSIALPQEFAALTKELNLCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPGGVSSEVEVLKALKSLFEHHKALDEKVRERLRMALERVAVLEEELELSNQEALNLRDQLSRRRSGLEEPGKDGDGQTLANGLGPVGESNRRTAELEEALERQRAEVCQLRERLAVLCRQMSQLEEELGTAHRELGKAEEANSKLQRDLKEALAQREDMEERITTLEKRYLSAQREATSLHDANDKLENELASKESLYRQSEEKSRQLAEWLDDAKQKLQQTLQKAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEKNQELQRARQREKMNDDHNKRLSETVDKLLSESNERLQLHLKERMGALEEKNSLSEEIANMKKLQDELLLNKEQLLAEMERMQMEIDQLRGRPPSSYSRSLPGSALELRYSQAP-TLPSG--APLDPYG-AGSG---RAGKRGRWSGAKDESSK--DWDRSAPAGSIPPPFPGELDGSDEEEAEGMFGAELLSPSGQADVQTLAIMLQEQLEAINKEIKLIQEEKETTEQRAEELESRVSSSGLD-------SLGRYRS-SCSLPPSLTTSTLASPSPPSSGHSTPRLAPPSPAREGTDKTNHVSKEEAGVPRGEGPAVPGDTPPPTPRSARLERMAQAL--ALQAGSPED---GAPPRGSESTPDSLHKAPKRKSIKSSIGRLFGKKEKGRMGPPGRESVSLAGTPSDETLATDPLGLAKLTGPGDKDRRNKRKHELLEEACRQGLPFAAWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMANLSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPASSRTPTGNVWMTHEEMESLTAATKPETKEISWEQILAYGDMNHEWVGNDWLPSLGLPQYRSYFMESLVDARMLDHLNKKELRGQLKMVDSFHRVSLHYGIMCLKRLNYDRKDLERRREESQTQIRDVMVWSNERVMGWVSGLGLKEFATNLTESGVHGALLALDETFDYSDLALLLQIPTQNAQARQLLEKEFSNLISLGTDRRLDEDSAKSFSRSPSWRKMFREKDLRGVTPDSAEMLPPNFRSAAAGALGSPGLPLRKLQPEGQTSGSSRADGVSVRTYSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "X1WCJ5-1", "uniprot_id": "X1WCJ5_DANRE", "id": "X1WCJ5-1", "name": "", "aln": "MMCEVMPTISEDGRGGAGGGPSSPAGGGGGMGGGAGGMGGGYGGREARGGDEGGSTGNLESLMVNMLTERERLLESLRETQESLGTAQLRLRELGHEKDSLQRQLSIALPQEFAVLTKELNVCREQLLEREEEIAELKAERNNTRLLLEHLECLVSRHERSLRMTVVKRQAQSPAGVSSEVEVLKALKSLFEHHKALDEKVRERLRVALERVAVLEEELESSTNEVLSLRDQIKRRERGLDN-GKE----RLPNGPSSILDDGEIDRQREGEIERQRAELSQLKERLALMCRQVGEIEEQLTTARRELAKSEEANQKLQRDVKEALCQREDMEERITTLERRYLSAQREATSLHDIKDKLENELASKESLYRQSEEKNRQLQERLDDAKQKLQQTLQRAETLPEIEAQLAQRVAALNKAEERHGNFEERLRQLEAQLEEKNQELQRARQRERMNDEHNKRLSDTVDKLLSESNERLQLHLKERMAALEEKNALSEELANMKKIQDDLLANKDQLIAELERLQLELDQLRGRPGSSYSRSLPGSALELRYSQGGGSLPAGSTTHLEHYGNTGTGGVVRRTHRGRWSGAREDASKYGDWESGALLGSGFEGGVEDRCSDDEEDRETLFGSELLSPSGQTDVQTLAIMLQEQLEAINKEIKLIQEEKESTELRAEEIESRVSSVALDGPPIPPTSLGRDSTGRGFIPPSLTSSTLASPSPPSSGHSTPRLP-HSPARE-TDRQNNKEDDRS-------LALLDSTPPPTPRALRLDRMTHTHPGALLDDSREFRSLSADGSSSNSSQDSLHKASKKKSIKSSIGRLFGKKDKVRMGQPGRESTSLASTPSDDLGTVDPLGLTKMAGPVDKDRRSKKKHELLEEACRQGLPFASWDGPTVVSWLELWVGMPAWYVAACRANVKSGAIMANLSDTEIQREIGISNPLHRLKLRLAIQEMVSLTSPSAPASTRSSTSNVWMTHAEMESLTAATKPELKEISWDQILAYGDMNHEWVGNDWLPSLGLPQYRSYFMESLVDARMLDHLTKKELRGQLKMVDSFHRVSMHYGIMCLKRLNYDRKELERRRDESQHQNKDVMVWSNERVMCWVQSIGLKEYADNLTESGVHGALLALDDTFDYTDLALLLQIPNQNTQARQLLEKEYNSLISMGTERRPDEDGTKTFTRSPSWRKMFREKDLRGVTSDSSETLPANFR---ASAISTPSVTLRKVQSD----ASPRAESGSVRTYSC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************** *:. ** **.* *:** ***.**********:***:*:.*.*****************************.******:****************************************************.*******************************:************* *.:*.*.**:*:.**. **:: **: *.** .. :... : * :******:.**:****::***:.::**:* **:***.*:****.*****:****.*************:************** :********************.*** * *************:*****************************************************:***:******:*********************.******:****:*****:**:** **:**:**:**:*:*:******* ******************. :**:* : *: * :*:* * :******.:::.** **: .* ** : ..***: * :**:********:****************************:** ****:****** .** **** : :*****:******************. ***** **: *: .:.: *: ..*******: **:**::: ** .* * .. .*:.: ******.*:**************:* *** ***:* ***.****: :.*****:*::** *****.*:****************:***************************************************************************:*:.*.****** *******:**** *****:*******************************************.******************:***************:*****:*** * :*********** **..:****:* ***************:****:*********.**:*********:..***:**:** ***.:*:*:******************.**:* **.*** *.*:.:*.:.***:*.: .*.**:. *******", "identical_positions": 917, "similar_positions": 177, "identity": "73.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100316-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35393-1", "uniprot_id": "EFNB3_MOUSE", "id": "O35393-1", "name": "Ephrin-B3", "aln": "MGAPHFG-------PGGVQVGALLLLGFAG--LVSGLSLEPVYWNSANKRFQAEGGYVLYPQIGDRLDLLCPRARPPGPHSSPSYEFYKLYLVEG-AQGRRCEAPPAPNLLLTCDRPDLDLRFTIKFQEYSPNLWGHEFRSHHDYYIIATSDGTREGLESLQGGVCLTRGMKVLLRVGQSPRGGAVPRKPVSEMPMERDRGAAHSAEPGRDTIPGDPSSNATSRGAEGPLPPPSMPAVAGAAGGMALLLLGVAGAGGAMCWRRRRAKPSESRHPGP--GSFG--RGGSLGLGGGGGMGPRE-AEPGELGIALRGGGTADPPFCPHYEKVSGDYGHPVYIVQDGPPQSPPNIYYKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15768-1", "uniprot_id": "EFNB3_HUMAN", "id": "Q15768-1", "name": "Ephrin-B3", "aln": "MGPPHSG-------PGGVRVGALLLLGVLG--LVSGLSLEPVYWNSANKRFQAEGGYVLYPQIGDRLDLLCPRARPPGPHSSPNYEFYKLYLVGG-AQGRRCEAPPAPNLLLTCDRPDLDLRFTIKFQEYSPNLWGHEFRSHHDYYIIATSDGTREGLESLQGGVCLTRGMKVLLRVGQSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP--GSFG--RGGSLGLGGGGGMGPRE-AEPGELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGPPQSPPNIYYKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8RI02-1", "uniprot_id": "A0A2R8RI02_DANRE", "id": "A0A2R8RI02-1", "name": "Ephrin-B3", "aln": "MGIQTRGAWVAMAFSDWVSALGFLLIFLMESLAVDATNMEPVYWNTLNRRFGDERGYILYPQIGDRLDLVCPATSPAGPNSPPEYEFYKLYLVSTREQADRCEVMGAPNLLLTCDKPNSDMRFTIKFQEYSPNLWGHEFKNLRDYYIIATSDGTKEGIDSMRGGVCVTRGMKLVLKVGQTAYG--LPPKPK------PDPGRPNSKIPDTE-----SGSKGGETSESGAVSASNIALISGGAGGAFILLIAIVIA--VVCYRRRKAKHSETHHPALTLSSLTPKRGSSGGTATGSSGGNNNGSEPSDIIIPLR---TSDSAYCPHYEKVSGDYGHPVYIVQEMPPQSPANIYYKV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * .. * . .:**: . *.. .:******: *:** * **:***********:** : *.**:*.*.********* *. ***. *********:*: *:******************:. :***********:**::*::****:*****::*:***:. * :* ** * * .:* *. : . *:. . . .*.:....:. ::*.*** :**:.:. * .:*:***:** **::**. .*: **.* * . *.. * .: :**.:: *.** ::*..:*******************: *****.******", "identical_positions": 176, "similar_positions": 93, "identity": "49.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100316-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q92914-1", "uniprot_id": "FGF11_HUMAN", "id": "Q92914-1", "name": "Fibroblast growth factor 11", "aln": "MAALASSLIRQKREVREPGGSRPVSAQRRVCPRGTKSLCQKQLLILLSKVRLCGGRPARPDRGPEPQLKGIVTKLFCRQGFYLQANPDGSIQGTPEDTSSFTHFNLIPVGLRVVTIQSAKLGHYMAMNAEGLLYSSPHFTAECRFKECVFENYYVLYASALYRQRRSGRAWYLGLDKEGQVMKGNRVKKTKAAAHFLPKLLEVAMYQEPSLHS-VPEASP-------SSPP--------AP-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9J0-1", "uniprot_id": "E7F9J0_DANRE", "id": "E7F9J0-1", "name": "Fibroblast growth factor", "aln": "MAALASSLIRQKRAVKDDQANRPIANKRKPCPKSNKSLCQKQILVLISKVRLCGGRRGRTDKRPEPQLKGIVTRLYSQHGYYLQMLPDGTMDGTRDENSCFSQFNLIPVGLRIVAIQGAKTGFYLGMNSEGYLYTSEHFNPECKFKESVFENYYVTYSSMLYRQSQSGRSWYIGINRDGQVMKGNRVKKTKAAAHFLPKVIEVAMYKEPSLHELVAEQSPPRKTVKTSDSPSHQNGRKEAPRADAS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************* *:: ..**:: :*: **:..*******:*:*:********* .*.*: **********:*:.::*:*** ***:::** ::.*.*::*********:*:**.** *.*:.**:** **:* **..**:***.******* *:* **** :***:**:*::::*********************::*****:*****. *.* ** *..* ** ", "identical_positions": 149, "similar_positions": 59, "identity": "60.57%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100316-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6X632-1", "uniprot_id": "GPR75_MOUSE", "id": "Q6X632-1", "name": "Probable G protein-coupled receptor 75", "aln": "MNTSAPLQNVPNATLLNMPP-LHGGNSTSLQEGLRDFIHTATLVTCTFLLAIIFCLGSYGNFIVFLSFFDPSFRKFRTNFDFMILNLSFCDLFICGVTAPMFTFVLFFSSASS---IPDSFCFTFHLTSSGFVIMSLKMVAVIALHRLRMVMGKQPNCTASFSCILLLTLLLWATSFTLATLATLRTN--KSHLCLPMSSLMDGEGKAILSLYVVDFTFCVAVVSVSYIMIAQTLRKNAQVKKCPPVITVDASRPQPFMGASVKGNGDPIQCT--MPALYRNQNYNKLQHSQTHGYTKNINQMPIPSASR----LQLVSAINFSTAKDSKAVVTCVVIVLSVLVCCLPLGISLVQMVLSDNGSFILYQFELFGFTLIFFKSGLNPFIYSRNSAGLRRKVLWCLRYTGLGFLCCKQKTRLRAMGKGNLEINRNKSSHHETNSAYMLSPKPQRKFVDQACGPSHSKESAASPKVSAGHQPCGQSSSTPINTRIEPYYSIYNSSPSQQESGPANLPPVNSFG--FASSYIAMHYYTTNDLMQEYDSTSAKQIPIPSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95800-1", "uniprot_id": "GPR75_HUMAN", "id": "O95800-1", "name": "Probable G protein-coupled receptor 75", "aln": "MNSTGHLQDAPNATSLHVPH-SQEGNSTSLQEGLQDLIHTATLVTCTFLLAVIFCLGSYGNFIVFLSFFDPAFRKFRTNFDFMILNLSFCDLFICGVTAPMFTFVLFFSSASS---IPDAFCFTFHLTSSGFIIMSLKTVAVIALHRLRMVLGKQPNRTASFPCTVLLTLLLWATSFTLATLATLKTS--KSHLCLPMSSLIAGKGKAILSLYVVDFTFCVAVVSVSYIMIAQTLRKNAQVRKCPPVITVDASRPQPFMGVPVQGGGDPIQCA--MPALYRNQNYNKLQHVQTRGYTKSPNQLVTPAASR----LQLVSAINLSTAKDSKAVVTCVIIVLSVLVCCLPLGISLVQVVLSSNGSFILYQFELFGFTLIFFKSGLNPFIYSRNSAGLRRKVLWCLQYIGLGFFCCKQKTRLRAMGKGNLEVNRNKSSHHETNSAYMLSPKPQKKFVDQACGPSHSKESMVSPKISAGHQHCGQSSSTPINTRIEPYYSIYNSSPSQEESSPCNLQPVNSFG--FANSYIAMHYHTTNDLVQEYDSTSAKQIPVPSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IPI9-1", "uniprot_id": "A0A0R4IPI9_DANRE", "id": "A0A0R4IPI9-1", "name": "", "aln": "MCTMNSTAWPLDLAEFAKPRGFNSSQSQSASAGGWALIHTATLASCSLLLVLIFCLGSYGNLVVFLSFFDPAFRKFRTNFDFMILNLSFCDLFICCVTAPMFALVLFLDAGDNNGGVSKGFCFAFHLTSSGFIIMSLETVAVIALHRLRMVLGQQPNRTASFPCTLALTALLWTSSFTLAALVTLRAYPRSSGPCLPHFGLTGNKAKVVLYVYIADFAFCVGVVSISYLMIAQALRKNAQVRKCP-IITVDATRPPASHPPLIAAGFEGMQCTVQVPSLYRNQTYNKLQHVQTHSFTRRTNQPLVPGAATGATCCQLVTSVNLATAKDSKAVVTCVVIVISVLLCCLPLGISLAQDMVSPESSFVHYQFELCGFALIFLKSGINPFVYSRNSAGLRRRVLCCLQWLTLGFLCCKHKTRLHAMGKGSLEVNRNKSSHHETNSAYMLSPKPQRRLVDQACGPSHSRDSMPSPCATAGRKPRPPSTSTPINTRIEPYYSIYNSSPSAGPSSPNSLQPVNSQTTPFAKSYVAMHYHIHQETLQDFDSTSAHQIPIPSV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : : : * : .:* * . * :******.:*::**.:*********::********:*********************** ******::***:.:... :...***:********:****: ************:*:*** ****.* : ** ***::*****:*.**:: .* *** .* .:.*.:* :*:.**:***.***:**:****:*******:*** :*****:** . : .. : :**: :*:*****.****** **:.:*: ** *.*: ***:::*::************:**:***:*********.* ::* :.**: ***** **:***:***:***:**********:** **:: ***:***:****:*****.**:*********************:::**********::* ** :**:: *:******************** *.* .* **** **.**:****: :: :*::*****:***:***", "identical_positions": 337, "similar_positions": 124, "identity": "60.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100316-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K9R9-1", "uniprot_id": "A0A0G2K9R9_RAT", "id": "A0A0G2K9R9-1", "name": "Proteasome activator complex subunit 4", "aln": "---------------------------------------MEAPERAGGGEPPEPGGRPVLGPRAFVPQKEIVYN-------------------------------------------------KLLPYAERLDAESDLQLAQIKSNLGRAVQLQELWPGGLFWTR----------------------------------------------KLSTYIRLYGRKFSKE-------------------------------------DHVLFIKLLYELVSIPKLEISMMQGFARLLINLLKKKELLSRDDLELPWRPLYDMVERILYSKTEHLRLNSFPN------------------SIENVLKTLVKSCRPYFPADATAEMLEEWRPLMCPFDVTMQKAVSYFEIFLPTSLPPELHHKGFKLWFDELIGLWVSVQNLPQWEGQLVNLFARLATDNIGYIDWDPYVPKIFTRILRSLNLPVGSSQVLVPRFLTNAYDIG--------HAVIWITAMMGGPSKLVQKHLAGLFNSITSFYHPSNNGRWLNKLMKLLQRLPNSVVRRLHRERFKKPSWLTPVPESHKLTDEDVTDFVQCIIQPVLLAMFSKTG--SLEAAQALQNLALMRPELVIPPVLERTYPALET--LTEPHQLTATLNCVIGVARSLVSGSKWFPEGPTHMLPLLMRALPGVDPNDFSKCMITFQFIGTFSTLVPLVDCSSVLQERNDLTEIEKELCSATAEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSKDIFMVALQKVFNFSVSHIFETRVAG----------RMVADMCRAAVKCCPEESLKLFVPHCYGVITQLTMNDDVLNE----EELDKELLWNLQLLSEITRVDGKKLLLYREQLVKILQRTLH-LTCKQGYTLSCNLLHHLLRSTTLIYPTEYCSVPGGFNKPPSEYFPIKDWG-KPGDLWNLGIQWHVPSSEEVSFAFYLLQSFLQPELIKLQRCGDG-ELEMSRDDILQSLTIVHNCLIGSGNLLPP--------------------LKGEPVTNLVPSMVSLEETKLYTGLEHDLSKEN---------------------------HREVIASVIRKLLS-----HILDNSEDDTKSLFLIIKIIGDLLQFQGSHKHEFDSR----------------WKSFNLVKKSMEN-------RLHGKKQHIRALLIDRVMLQHELRTLTVEGCEYKK----IHQDMIRDLLRLSTSSYSQVRNKAQQTFFAALGAYNFCCRDIIPLVLEFLRPDRKDVTQQQFKGALYCLLGNHSGVC---------LANLHDWDCIVQTWPALVSSGLSQAMSLEKPSIVRLFDDLAEKIHR-----------QYETIGLDFTIPKSCAAIAELLQQSKNPSISQTLLSPEKIKEGQKRQQDKNADAVRNYECLVNTLLDGVEQRNLPWKFEHIGIGLLSLLLRDDRVLP-LRAIRFFVENLNHDAIVVRKMAISAVAGILKQLKRTHKKLTINPYEISGCPKPATVLAGDRPDNHWLHYDSKNIPRTKKEWESSCFVEKTHWGYYNWPKNMVVYAGVEEQPKLGRSREDMTEAEQIIYDRFSDPKFVEQLITFLSLEDRKGRDKFSPRRFCLFKGIFRNFDDAFLPVLKPHLERLVADSHES----TQRCVAEIIAGLIRGSKHWTFEKVEK----LWELLCPLLRTALSNMTVETYNDWGTCIATSCESRDPRKLHWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPK-LTQVYKNVRERIGSVLTYIFMIDVSLPNTAPTTSPCIPEFTARVLEKLKPLTDVDEEIQNHVME---ENGIGEEDE---RTQGIKLLKTILKWLMASAGRSFSTAVKEQLQLLPLFFKIAPVENDNSYDELKRDAKLCLSLMSQGLLYPQQVPLILQVLSQTARSSSWHARYTVLTYLQTMVFYNLFIFLNNEDAVKDIRWLIIRLLEDEQLEVREMAATTLSGLLQCNFLTMDSAMQSHFEQLCKTKLPKKRKRDPGSVGDTIPSAELVKRHAGVLGLGACVLSSP--YDVPTWMPQLLMNLSAHLNDPQPIEMTVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPCYYA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SSW2-1", "uniprot_id": "PSME4_MOUSE", "id": "Q5SSW2-1", "name": "Proteasome activator complex subunit 4", "aln": "---------------------------------------MEAPERAGGGEPPEPGGRPVLGPRAFVPQKEIVYN-------------------------------------------------KLLPYAERLDAESDLQLAQIKSNLGRAVQLQELWPGGLFWTR----------------------------------------------KLSTYIRLYGRKFSKE-------------------------------------DHVLFIKLLYELVSIPKLEISMMQGFARLLINLLKKKELLSRDDLELPWRPLYDLVERILYSKTEHLRLNSFPN------------------SIENVLKTLVKSCRPYFPADSTAEMLEEWRPLMCPFDVTMQKAISYFEIFLPTSLPPELHHKGFKLWFDELIGLWVSVQNLPQWEGQLVNLFARLATDNIGYIDWDPYVPKIFTRILRSLNLPVGSSQVLVPRFLTNAYDIG--------HAVIWITAMMGGPSKLVQKHLAGLFNSITSFYHPSNNGRWLNKLMKLLQRLPNSVVRRLHRERFKKPSWLTPVPESHKLTDEDVTDFVQCIIQPVLLAMFSKTG--SLEAAQALQNLALMRPELVIPPVLERTYPALET--LTEPHQLTATLNCVIGVARSLVSGSKWFPEGPTHMLPLLMRALPGVDPNDFSKCMITFQFIGTFSTLVPLVDCSSVLQERNDLTEIEKELCSATAEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSKDIFMVALQKVFNFSVSHIFETRVAG----------RMVADMCRAAVKCCPEESLKLFVPHCYGVITQLTMNDDVLNE----EELDKELLWNLQLLSEITRVDGKKLLLYREQLVKILQRTLH-LTCKQGYTLSCNLLHHLLRSTTLIYPTEYCSVPGGFNKPPSEYFPVKDWG-KPGDLWNLGIQWHVPSSEEVSFAFYLLDSFLQPELIKLQCCGDG-ELEMSRDDILQSLTIVHSCLIGSGNLLPP--------------------LKGEAVTNLVPSMVSLEETKLYTGLEHDLSREN---------------------------YREVIASVIRKLLS-----HILDNSEDDTKSLFLIIKIIGDLLHFQGSHKHEFDSR----------------WKSFNLVKKSMEN-------RLHGKKQHIRALLIDRVMLQHELRTLTVEGCEYKK----IHQDMIRDLLRLSTSSYSQVRNKAQQTFFAALGAYNFCCRDIIPLVLEFLRPDRKDVTQQQFKGALYCLLGNHSGVC---------LANLHDWDCIVQTWPALVSSGLSQAMSLEKPSIVRLFDDLAEKIHR-----------QYETIGLDFTIPKSCAAIAELLQQSKNPSISQTLLSPEKIKEGQKRQQDKNADALRNYECLVNTLLDGVEQRNLPWKFEHIGIGLLSLLLRDDRVLP-LRAIRFFVENLNHDAIVVRKMAISAVAGILKQLKRTHKKLTINPYEISGCPKPTKILAGDRPDNHWLHYDSKNIPRTKKEWESSCFVEKTHWGYYNWPKNMVVYAGVEEQPKLGRSREDMIEAEQIIYDRFSDPKFVEQLITFLSLEDRKGRDKFSPRRFCLFKGIFRNFDDAFLPVLKPHLERLVADSHES----TQRCVAEIIAGLIRGSKHWTFEKVEK----LWELLCPLLRTALSNMTVETYNDWGTCIATSCESRDPRKLHWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPK-LTQVYKNVRERIGSVLTYIFMIDVSLPNTAPTTSPCIPEFTARVLEKLKPLTDVDEEIQNHVME---ENGIGEEDE---RTQGIKLLKTILKWLMASAGRSFSTAVKEQLQLLPLFFKIAPVENDNSYDELKRDAKLCLSLMSQGLLYPQQVPLILQVLSQTARSSSWHARYTVLTYLQTMVFYNLFIFLNNEDAVKDIRWLIICLLEDEQLEVREMAATTLSGLLQCNFLTMDSAMQIHFEQLCKTKLPKKRKRDPGSVGDTIPSAELVKRHAGVLGLGACVLSSP--YDVPTWMPQLLMNLSAHLNDPQPIEMTVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPCYYA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14997-1", "uniprot_id": "PSME4_HUMAN", "id": "Q14997-1", "name": "Proteasome activator complex subunit 4", "aln": "---------------------------------------MEPAERAGVGEPPEPGGRPEPGPRGFVPQKEIVYN-------------------------------------------------KLLPYAERLDAESDLQLAQIKCNLGRAVQLQELWPGGLFWTR----------------------------------------------KLSTYIRLYGRKFSKE-------------------------------------DHVLFIKLLYELVSIPKLEISMMQGFARLLINLLKKKELLSRADLELPWRPLYDMVERILYSKTEHLGLNWFPN------------------SVENILKTLVKSCRPYFPADATAEMLEEWRPLMCPFDVTMQKAITYFEIFLPTSLPPELHHKGFKLWFDELIGLWVSVQNLPQWEGQLVNLFARLATDNIGYIDWDPYVPKIFTRILRSLNLPVGSSQVLVPRFLTNAYDIG--------HAVIWITAMMGGPSKLVQKHLAGLFNSITSFYHPSNNGRWLNKLMKLLQRLPNSVVRRLHRERYKKPSWLTPVPDSHKLTDQDVTDFVQCIIQPVLLAMFSKTG--SLEAAQALQNLALMRPELVIPPVLERTYPALET--LTEPHQLTATLSCVIGVARSLVSGGRWFPEGPTHMLPLLMRALPGVDPNDFSKCMITFQFIATFSTLVPLVDCSSVLQERNDLTEVERELCSATAEFEDFVLQFMDRCFGLIESSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSKEIFMVALQKVFNFSTSHIFETRVAG----------RMVADMCRAAVKCCPEESLKLFVPHCCSVITQLTMNDDVLND----EELDKELLWNLQLLSEITRVDGRKLLLYREQLVKILQRTLH-LTCKQGYTLSCNLLHHLLRSTTLIYPTEYCSVPGGFDKPPSEYFPIKDWG-KPGDLWNLGIQWHVPSSEEVSFAFYLLDSFLQPELVKLQHCGDG-KLEMSRDDILQSLTIVHNCLIGSGNLLPP--------------------LKGEPVTNLVPSMVSLEETKLYTGLEYDLSREN---------------------------HREVIATVIRKLLN-----HILDNSEDDTKSLFLIIKIIGDLLQFQGSHKHEFDSR----------------WKSFNLVKKSMEN-------RLHGKKQHIRALLIDRVMLQHELRTLTVEGCEYKK----IHQDMIRDLLRLSTSSYSQVRNKAQQTFFAALGAYNFCCRDIIPLVLEFLRPDRQGVTQQQFKGALYCLLGNHSGVC---------LANLHDWDCIVQTWPAIVSSGLSQAMSLEKPSIVRLFDDLAEKIHR-----------QYETIGLDFTIPKSCVEIAELLQQSKNPSINQILLSPEKIKEGIKRQQEKNADALRNYENLVDTLLDGVEQRNLPWKFEHIGIGLLSLLLRDDRVLP-LRAIRFFVENLNHDAIVVRKMAISAVAGILKQLKRTHKKLTINPCEISGCPKPTQIIAGDRPDNHWLHYDSKTIPRTKKEWESSCFVEKTHWGYYTWPKNMVVYAGVEEQPKLGRSREDMTEAEQIIFDHFSDPKFVEQLITFLSLEDRKGKDKFNPRRFCLFKGIFRNFDDAFLPVLKPHLEHLVADSHES----TQRCVAEIIAGLIRGSKHWTFEKVEK----LWELLCPLLRTALSNITVETYNDWGACIATSCESRDPRKLHWLFELLLESPLSGEGGSFVDACRLYVLQGGLAQQEWRVPELLHRLLKYLEPK-LTQVYKNVRERIGSVLTYIFMIDVSLPNTTPTISPHVPEFTARILEKLKPLMDVDEEIQNHVME---ENGIGEEDE---RTQGIKLLKTILKWLMASAGRSFSTAVTEQLQLLPLFFKIAPVENDNSYDELKRDAKLCLSLMSQGLLYPHQVPLVLQVLKQTARSSSWHARYTVLTYLQTMVFYNLFIFLNNEDAVKDIRWLVISLLEDEQLEVREMAATTLSGLLQCNFLTMDSPMQIHFEQLCKTKLPKKRKRDPGSVGDTIPSAELVKRHAGVLGLGACVLSSP--YDVPTWMPQLLMNLSAHLNDPQPIEMTVKKTLSNFRRTHHDNWQEHKQQFTDDQLLVLTDLLVSPCYYA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA52Z1E4-1", "uniprot_id": "A0AA52Z1E4_DANRE", "id": "A0AA52Z1E4-1", "name": "", "aln": "---------------------------------------MKKEQAEILG---------------FVPQKEIVYN-------------------------------------------------KLLPYADQLDRESNDILAQIKGNLGRAVQLRELWPGVLFWTR----------------------------------------------KLSTYLRLYGRKFSKE-------------------------------------DHVLFIKLLYELVTIPKLEISMMQSFARLLVNLLKKKELLSRDDLELPWRPLYDLYESILYSKTEHLGLNWFPNYRAEASTKQKMLNIVRKRSVENVLKTLVKSCRVYFPESATQEMLDEWRPLLCPFDVTMQKAIGYFELFLPTIMPPEQHDKGFKLWFDEMMNLWVSVQNLPAWEGNLVNLFARLANDNIGYVNWDPYIPKIFTRILRSFNLPVGTSQMVVPRYLTNSYDIG--------HVVLWISSMLGGPQNQSQKQLNGLFSSIASFYHPSNNGRWLMKLMKLLQRLPASIVRRLHRERYKKPCWITPVPSTHKLTDQDVTDFVESMKQPVLMAMFSKTG--SMDAAQALQNLALMRPELVIPPVLEKTYPAMET--LTEPHQLTATLSCMIGMARSLLSGGRHYPEGPAHVLPLLMRALPGVDPNDFSKCMITFQFIATFTTLVPLVDCSSALHDKNDLTEMERELCSASAEFEDFVLQFMDRCFALIDSSTLEQTREETETEKMTHLESLVELGLSSTFSTILTQCSMEIFKVALEKVFNFATTNIFETRVAG----------RMVADMCRAASKCHPAESLRLFVPHCCNAITHLTANEDVSNE----EELDKELLWNLQLLSEVTRVDGEKLLPYRTQLVQILQLTLR-LRCKQGYSLACNLLHHVLRSTALIYPTDYCSVPGGFSRPLQEYLPIKDWG-RPGDLWNLEIQWHVPSTEETAFVFYVLDLLLQPELQRLQRYAQG-EQEMSRDDVLQSLCIVQHCLLGAGSMLPP--------------------LDGSTVTGLVPSMVNLEETKLYIGVDYDQSREN---------------------------YREAVCKVMRQLLH-----YILEHSEDDTKSLFAIIKIISDLMHFKGSHKHEFDSR----------------WKSFTLVKKSMEN-------RLHGKKQHIRALLIDRVLLQHEMRKLLVEGCEYKT----VHQDLLRDLLRLSTSTYSQVRSKAQNVLFTALGTYNFCCRDITPRVLEFLEPTRTDVTQQQFKGALYCLLGNHCGVC---------LANLHDWDCIAQTWPAIVRSGLSSAMSLEKPSIVRLFDDLADKVHR-----------QYETIGIDFTVPENAVFLGRSITNSSQPTPHMSTPEDQELQQGLAVQQAKNREAEQKYEKLVKDLLECLDDRDLPWKFEHIAIGFLSLLLRDDYPLP-APAVFFFVQSLNHDALVVRKMAIAAVAGILKQLKRPRKKIPVNPCDISGVTEPEELEAGDRPGNDWLQYHSESLPNSQQDWDAFCFVEKTHWGYYSWPKKLMVYAPAAEQPKD-LAPDTMSEREAIINDHFTDPMFINQLIKFLSLEDRKGKDKFNPRRFCLFKGLFRNYSDAFLPVLKPHMERLANDSHES----TQRCVAEIIAGLIRGSKHWSFGKVEA----LWAFLIPLMRTALSNITVETYADWGTCVATACESRDPRKLHWLLEMLMECPLSGEGGSFVDACHLYVLQGGLAQQEWRVPELLHRLLSYLEPK-LTQVYKNVRERIGSVLTYIFMIDVALPYTLPTKSPHIAEFTERILTQLKPLIEGDEEIQNHVVE---ENGVGEQDE---RTQAIKLLKTVLKWLMASAGRSFSTPVPQQLQLLPLLFKIAPVENDDSYDELKRDAKTCLSLMSQGLLYPEQIPMVLAVLHEIAGSSSWHARYSVLTYLQTMVFYNLFTILSSEQCVQGVRALVIRLLEDEQLEVREMAATTLSGFLQCNFLAMDSSMQTHFEALCKTRLPKKRKRDVGSVMDTIPSVDLVRRHAGVLGLSACILSSP--YDVPTWMPQLLMDLSAHLNDTQPIEMTVKKTLSNFRRTHHDNWLEHKQQFTDDQLVVLTDLLVSPCYYA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43583-1", "uniprot_id": "BLM10_YEAST", "id": "P43583-1", "name": "Proteasome activator BLM10", "aln": "MTANNDDDIKSPIPITNKTLSQLKRFERSPGRPSSSQGEIKRKKSRLYAADGRPHSPLRARSATPTLQDQKLFNGMDSTSLLNERLQHYTLDYVSDRAQHMKNIYDPSSRWFSRSVRPEFPIEEFLPYKTESHEDQAKYLCHVLVNLYIAISSLDIQGLISISSKDLADLKKEVDDLALKTDLFRLSNNTAENDLLGNDIADYDDAEGLEDELDEYFDLAGPDFNATGKITAKSATIVNVNHWTNELKNCLHFDFPVALRKSLATVYYYLSLVQGQKVYRQMHVDMFERLVSLDDDRTNFTELLQKQGLLLDHQIMLNFLCEFLPYPDPDYARYELSS--------------KEDLQLFRLLLKHAHNAKPFFDKSKESLLVDTMNFLLS--SLAPSTMMAVMPIVTSVVPYHYHIHSKIIDYFPFCYSIWSSVSANVAIDTHMYDFVGSISKDVHNKILSSEHEKDVVGVEFGEFGIFTDDQMTFMFNRLQGHLRTDGQIHSYSRTVKPFVYAINGSKKDRFFEKLVSLAKAIETFIHPSNNGFWTKPNAKFVHAFIKSYHGRVKYEEDICARGVTNGICLTSFCHEEIVEIFLNIISLGSQNKNPDIANYYISCFAYLLELDPSNAYLIYDKILIDLYDTLADQFINSRHRIISSLKQFTRVIR-FIVMDKLYRVHITNVLSMLVSKLDMNDTNLTSNLINGIVSIAAFIPIQDLTGEDDYISFESDTLPLVQQHFYHIKCGESSKTFRVDDELLNNAFKASTTVFQSMLKVYVEKIFQLVDVDLEDSLVTKINQTTMILQESMDDKIFNYFASLLQRNFWSNDSFKEKDPNYELVTIPLAALVRRNNGLSKELVRTLLFHIKEQIKRGAGSVRSTSEIQQRDVKLVLYLTALNDVLRQCHESLLEYSDELITFMKYLYDNVTNPPLDVITSIVIHSALATLCTTEITDCRLFPEDSKIPEKDRWGGLQFDPRRFDKQHLSFQWHVPSSDEITLSISILESLSEYCINNVEELMKAPRHDSEYGDMIQKYVLVMTHTLSGSSLLFDPDFNKYRTQSNLSYREKLILLKNIRENNCDPQELDIDIEQIRSGKDDEDYIESKDIEAGLNAGVSDVVQLRDEFPDELIVDEEVVSEMPSGVNTPIAGTHGTDNSAMSSDLAFRDLDIYTCNYYFGNTTEEKLQNPQYLQVHRVRARIGHFFHKLYVFLSTNFENNTNMFQILLHGLKVWFTDLGQETVFNEDPNAFIDVDFLENVQSLSHVNEPFTRTNFAIRANSLHQSRVLLHSTNRKASKLENLLLVDIIQLATSLY-PDIYKPAQGTLVHCMKQLVGSYGVVINKIIPSLEKAIKDHDYMKIQVILNVLLIKKIHRKLMTDYKDIGRLIFLLIECCRVNELEIGMYADKILTDIVIGIKIPSSVCVISDQAFLPLAPPDGTINLQVEAVKLAKKKKREYYLSLLVDLQDKLLDKLD--NEKDMGWKIRMFILRFVTQIQSNLESKPDKRAVFSIISQISTKHPEIIHLVVKSLLSTCNKIISLSDYEYDITRAYKNEFNPSFVEILDTSTTSFPKTFTEEMNNFDN--PKYFIDLRAYVGWLCWGRLMYVMS-----PKALKLNLRENELEVLKTAGHLLTREFLRDVTMNLVQDNETRGVFSSGNVSFFSLVILLISSGFCELNMSDLFELCESYYNKDDKASMIMSVEIVAGLVCGSKFMSVSDLDKRDTFIENFLAKCLDYELNHDAFEIWSTLAWWLPAVVDLRRSKTFFCHFINADGMFDRESDAATHQTSKIYMLRSILMSMEFRAPDVGKLFDELVFDHPYDQVRQAVAKLLTTLVQNQSNPSISDPTTLLEAERNDPDGLGLPLKSVPEKVDAYIKKQFEIIKNLEDSVVGLNPQQFIKTDYFYRTSTIFYWIKEMARGPNKVLLVPYLVDYVLPFLIGLVKHKDVCALASLDPVRLYAGLGYMPIRKNHVAAIVDYVCSSNVALSSNQTKLQLAFIQHFLSAELLQLTE-EEKNKILEFVVSNLYNEQFVEVRVRAASILSDIVHN--WKEEQPLLSLIERFAKGLDVNKYTSKE----RQKLSKTDIKIHGNVLGLGAIISAFPYVFPLPPWIPKQLSNLSSWARTSGMTGQAAKNTISEFKKVRADTWKFDRASFNTEELEDLEGVLWRSYYA-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : . . *.: ::* ::*** . . :. *.:: ** *:. :: : :: :*. *: * * .*. ::.*: ::.:.*:: :. * : : .***.: .* * : : :: :* . :.. .: .:* . .:..: :* . ::: . *:. .:: .. : : :. .. .. : :* .:* **. : :: ::.. ::.* . : . : .:. : .:.: .. . .: . * . . . :: :: *. .. ::* .* .:* :* ****** * *::: : * *:: *. . :* .: .:::.::. : . .. . :.. * :* .. *: :* * :: :.. *:: ::*. . : * :: .: : :::*.:*: * *.* *: : : *.:* .: *.. .. : ..* : :: *. :* : .: . :. . : :: .**::.*..:: * :.* : : :*:**: .: : .. :. .:*: * : * .*. . ::. . . .. :: * :*: * *.:: * ..** * :*: ::: : ::. ::* * : *: .* . . * .: ::. : * :* :******::* :: : :*: : : : .:: .. . : . .*::*. :* :....:* *.. .. *. :.:: :: * : : *. .*.:. : : : ::* .:. * :.* * .: :.:::. * : ::...:** *** * : * : *: :. : *: * ::: : * : : :.: * * :.. * *: ** . .: * :* : .: *:*.: * : **: * .:: . : : : .* **: * : : * :.:.:*.. :. . *. . : :: . :: . . : : *: ::::: **:. : : ::: : : * *: ::..:. . : ::.: :: . ::: . . .. :* : * . . : : :: : . .: : ::: *: * : : * : ** * * : . . . : :.: ::*.: :. *.. ...:*. :: ...* : ..: .* . ::. : .**:***: ***. :. .:: : :* : *.: :.* : . :.: : * .:.:. : ...: ::.::*:*:. * . *:*.*:: : : . : : ** : * : : ::: .:: * * . .: * .: : : * .::: :. :* : : :*: : .*:: *: * . .. : * * * *. *::.: . *. : :. : .::. :: : . : * : *:::* :: :*: : . *: : :. :: * ::: :*** **: **.::: :..: :* :.* :* . . * :: *..****.* : : * : :*.*:*: * :**: . . :.*:*:*:*::.: *.* .: .*. ::* * .:* . * ", "identical_positions": 247, "similar_positions": 699, "identity": "11.34%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100316-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6KC51-1", "uniprot_id": "ABLM2_RAT", "id": "Q6KC51-1", "name": "Actin-binding LIM protein 2", "aln": "----------------MSAVSQPQAAHAPLEKP------ASTAILCNTCGNVCKGEVLRVQNKHFHIRCFVCKACGCDLAEGGFFVRQGEHICTRDYQRLYGTRCFSCDCFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKDCMCQKCSPPTLVGNSAHVAQG------------------------------------LRSCGGCGLEIKNGQALVALDKHWHLGCFKCKTCGKLLNAEYISKDGLPYCEADYHTKFGIRCDGCEKYITGRVLEAG-EKHYHPSCALCVRCGQMFSEGEEMYLQGSSIWHPACRQAARTE----------------------DKSKETRTSSESIVSVPASSTSGSPSRVIYAKLGDEILDYRDLAALPKNKAIYNIDRPDMISYSPYISHSAVGDRQSYGEGDQDDRSYKQCRTSSPSSAGSVS-LGHYTPTSRSPQHYSRP------------------------------------------------------------------------------GSESGRSTPSLSVHSDSRPPSSTYQQAPRHFHVPDTGVKDNIYR---KPPIYKQHAARRLDVEDSSFDQDSRKKTTWLLLKGDADTRTNSPDLDSQS--LSLSSGADQEPLQRMPGDSLYSRFPYSKPDTLPGPRKDGLDLRNANLAPCGADPDASWG--TREYKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BL65-1", "uniprot_id": "ABLM2_MOUSE", "id": "Q8BL65-1", "name": "Actin-binding LIM protein 2", "aln": "----------------MSAVSQPQAAHAPLEKP------ASTAILCNTCGNVCKGEVLRVQNKYFHIRCFVCKACGCDLAEGGFFVRQGEHICTRDYQRLYGTRCFSCDRFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSPPTLLGNSAHVAQG------------------------------------LRSCGGCGLEIKNGQALVALDKHWHLGCFKCKTCGKLLNAEYISKDGLPYCEADYHSKFGIRCDGCEKYITGRVLEAG-EKHYHPSCALCVRCGQMFSEGEEMYLQGSSIWHPACRQAARTE----------------------DKSKETRTSSESIVSVPASSTSGSPSRVIYAKLGDEILDYRDLAALPKNKAIYNIDRPDMISYSPYISHSAVGDRQSYGEGDQDDRSYKQCRTSSPSSAGSVS-LGHYTPTSRSPQHYSRP------------------------------------------------------------------------------GSESGRSTPSLSVHSDSRPPSSTYQQAPRHFHVPDTGVKDNIYR---KPPIYKQHAARRLDVEDSSFDQDSRKKTTWLLLKGDADTRTNSPDLDSQS--LSLSSGTDQEPLQRMAGDSLYSRFPYSKPDTLPGPRKDGLDLRNANLAPCGADPDASWG--TREYKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6H8Q1-1", "uniprot_id": "ABLM2_HUMAN", "id": "Q6H8Q1-1", "name": "Actin-binding LIM protein 2", "aln": "----------------MSAVSQPQAAPSPLEKS------PSTAILCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYICTLDYQRLYGTRCFSCDQFIEGEVVSALGKTYHPDCFVCAVCRLPFPPGDRVTFNGKECMCQKCSLPVSVGSSAHLSQG------------------------------------LRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCGKLLNAEYISKDGLPYCEADYHAKFGIRCDSCEKYITGRVLEAG-EKHYHPSCALCVRCGQMFAEGEEMYLQGSSIWHPACRQAARTE----------------------DRNKETRTSSESIISVPASSTSGSPSRVIYAKLGGEILDYRDLAALPKSKAIYDIDRPDMISYSPYISHS-AGDRQSYGEGDQDDRSYKQCRTSSPSSTGSVS-LGRYTPTSRSPQHYSRP------------------------------------------------------------------------------GSESGRSTPSLSVLSDSKPPPSTYQQAPRHFHVPDTGVKDNIYR---KPPIYRQHAARRSDGEDGSLDQDNRKKSSWLMLKGDADTRTNSPDLDTQS--LSHSSGTDRDPLQRMAGDSFHSRFPYSKSDPLPGHGKNGLDQRNANLAPCGADPDASWG--MREYKIYPYDSLIVTNRIRVKLPKDVDRTRLERHLSPEEFQEVFGMSIEEFDRLALWKRNDLKKKALLF------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GXT7-1", "uniprot_id": "A0AC58GXT7_DANRE", "id": "A0AC58GXT7-1", "name": "Actin-binding LIM protein 2", "aln": "--------------MPEEKAFHQQAVHSPLEQQK--GQRQSGPVPCQNCGKPCKGEVLRVQNKHFHIKCFVCKVCECDLAQGGFFVRQGEYICTVDYQRLYGTRCFSCEEFIEGEVVSALGKTYHPRCFVCATCKQPFPAGDRVTFNGKECICEKCTQPVPVN-STAPSQA------------------------------------VHNCCGCGKEFKSEQSLVALDKHWHLGCFKCKVCNKVLNAEYISKDGIPYCEADYHAMFGIQCETCKKYITGKVLEAG-EKHYHPTCARCARCDQMFGEGEEMYLQGSSIWHPPCRQAARME----------------------EKSKVTRTSSESITSAPASSASGSPSRVIYAKLGDELLDYKDLAALPKIKAIYNIDRPDMLSYSPYVSYP-VEDR-TFGEGD-GEKSPRQRRPSSPSSNSSLGGYGRYTP-SRSPQTYSRPDQYLSIKYTTQPENSHLLSVPTSGRSSAHGSARGSSPLPLYNSSGRNTPQAALPLNPTTLALLQQHNYIPYF-----RGSESGRSTPSLSTYSDGKSPSSTYVAAPRHFHIPETKVKDNIYR---KPPIYKQHASRTSWQDGD--DVDRKTRTSWMNLKTEIDG--QSPELDPRT--STHSLPTDMS----------QPNFPYNKSASLPGYGRNGIY-KAADLGEDEADHDSSWSG-MREYKVYPYDMLAVSHRVRVKLPRDVDRTRLERHLSPEDFYNVFRMTIEQFDRLALWKKNELKKKARLF------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8INN6-1", "uniprot_id": "Q8INN6_DROME", "id": "Q8INN6-1", "name": "", "aln": "MYILIYISIPKHPQTDKTRPIYPSTLGTELRTELGKTGQGKQKIYCAKCTKKCSGEVLRVADNHFHKACFQCCQCKKSLATGGFFTKDNAYYCIPDYQRLYGTKCANCQQYVEGEVVSTMGKTYHQKCFTCSKCKQPFKSGSKVTNTGKEVLCEQCVTGAPVSPSRQATGGGVSSPAPPAESPTRATAHQQHGSVISHKAHLKEDYDPNDCAGCGELLKEGQALVALDRQWHVSCFRCKACQAVLNGEYMGKDAVPYCEKCYQKGFGVKCAYCSRFISGKVLQAGDNHHFHPTCARCTKCGDPFGDGEEMYLQGSAIWHPRCGPGPSESGIILNGGGGTSSVVGGASNGNFTDTECDRMSSSALSEMYIRSRTPSFNGSLYSSSRKHYRTVSPGLILREYGRPNAEDISRIYTYS-YLTDAPHYLRKPIDPYDKTPLSPHFHRPSSYATTASNAGSVAGSRPPSRPHSRTRSAMKVLVDAIRSETPRPKSPGMNNEEPIELSHYPAAKKPPPGEQPKIERDDFPAPPYPYTDPERRRRYSDTYKGVPASDDEDENVENGKPNGKVKNGEEQQRLQREAEQLEKLNSGIGSAIAKDLKEHAKYRKWKQNNLDPRNASRTPSASKEPLYKLRYESPIGASPSRNLDHQKPFYEDEMFDRSTSYRGSLGKSLGNAPSYNAIHSYRSPPKPGYGFKTTTLPYIRNGFSSDFSYGGLGDKTHSTDLSCGKSEASVDSITEGDRRALMGGDLPASSTYSGALSYHYPQAGLIRRSLPNMSHSIISCANAKL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : *. . : * .* : *.****** :::** ** * * .** ****.::. : * ********:* .*: ::******::***** **.*: *: ** .*.:** .**: :*::* . :. * : . ..* *** :*. *:*****::**:.**:** * :**.**:.**.:**** *: **::* *.::*:*:**:** ::*:**:** *.:*.: *.:*********:**** * .. . .: * **.:: . * : * . :*:. . * : * . : :** *:: . * . . * * : *.** :: .* . : . *: :*. ..:.. .. . . .. . ..::. :: : . * : : . *:: . . . ... : . * :** :. . .*. . . : * : : * . .:.:. * :. * . . *. : ** * * . :: . : : : .:: : ", "identical_positions": 154, "similar_positions": 180, "identity": "19.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100316-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VH46-1", "uniprot_id": "AFAP1_RAT", "id": "Q8VH46-1", "name": "Actin filament-associated protein 1", "aln": "------------MEELIVELRLFLELLDHEYLTSTVREKKAVLTNILLRMQSSKGFEVKDHAQKAETNN-LPAPPQMPLPEIPQPWLPPDSGPPPLPTSSLPEGYYEEAVPLSPGKAPEYITSNYDSEAMGSSYESYDEEEEDGKGKKTQHQCHHEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKDTKLLCYKSSKDQQPQMELPLQGCSITYIPRDSKKKKHELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDPECSPPPSASVPVNKAELEKKLSSERPSSDGEGVVENGVTTCNGKEQAKRKKPSKSEAKGTVSKVTGKKITKIIGLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNSRWRERWCRVKDSKLILHKDRADLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPGALHYDYIDVEMSANVIQTAKQTFCFMNRRAVSTSPYLGSLSNGYAHPSGTALHYDDVPCVNGSLKNKKPPASSNG-------------------------------------------LPVKGRAPSS------------------------------QQKKVESAGG---VKRTASNAEQYKYGKNRVEADAKRLQSKEEELLKRKEALRNRLAQLRKERKDLRAAIEVNAGRKTQVALEDKLKRLEEECKQREAERVSLELELTEVKESLKKALAGGVTLGLAIEPKSGTSSPQSPVFRHRTLENSPISSCDTSDAEG-PLPVNSAAVLKKSQPSSSSSPCRGHVLQKAREWELKNGT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80YS6-1", "uniprot_id": "AFAP1_MOUSE", "id": "Q80YS6-1", "name": "Actin filament-associated protein 1", "aln": "------------MEELIVELRLFLELLDHEYLTSTVREKKAVLTNILLRLQSSKGFEVKDHAQKAEANN-LPAPPQMPLPEIPQPWLPPDSGPPPLPTSSLPEGYYEEAVPLSPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKDTKLLCYKSSKDQQPQMELPLQGCSITYIPRDSKKKKHELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDPECSPPPSTSAPVNKAELEKKLSSERPSSDGEGGVENGVTTCNGKEQAKRKKPSKSEAKGTVSKVTGKKITKIIGLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNSRWRERWCRVKDSKLILHKDRADLKTHLVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPGALHYDYIDVEMSANVIQTAKQTFCFMNRRAVSTSPYLGSLSNGYAHPSGTALHYDDVPCVNGSLKNKKPPASSNG-------------------------------------------VPVKGKAPSS------------------------------QQKKVETAGG---VKRTASNAEQYKYGKNRVEADAKRLQSKEEELLKRKEALRNRLAQLRKERKDLRAAIEVNAGRKTQAALEDKLKRLEEECKQREAERVSLELELTEVKESLKKALAGGVTLGLAIEPRSGTSSPQSPVFRHRTLENSPISSCDTSDAEG-PLPVNSAAVLKKSQPSSGSSPCRGHVLQKAKEWELKNGT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N556-1", "uniprot_id": "AFAP1_HUMAN", "id": "Q8N556-1", "name": "Actin filament-associated protein 1", "aln": "------------MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDVKDHAQKQETANSLPAPPQMPLPEIPQPWLPPDSGPPPLPTSSLPEGYYEEAVPLSPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKDTKLLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKHELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDSECPPPPSS--PVHKAELEKKLSSERPSSDGEGVVENGITTCNGKEQVKRKKSSKSEAKGTVSKVTGKKITKIISLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNSRWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALHYDYIDVEMSASVIQTAKQTFCFMNRRVISANPYLGGTSNGYAHPSGTALHYDDVPCINGSLKGKKPPVASNG-------------------------------------------VTGKGKTLSS------------------------------QPKKADPAAV---VKRTGSNAAQYKYGKNRVEADAKRLQTKEEELLKRKEALRNRLAQLRKERKDLRAAIEVNAGRKPQAILEEKLKQLEEECRQKEAERVSLELELTEVKESLKKALAGGVTLGLAIEPKSGTSSPQSPVFRHRTLENSPISSCDTSDTEG-PVPVNSAAVLKKSQAAPGSSPCRGHVLRKAKEWELKNGT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PMC5-1", "uniprot_id": "A0A8M9PMC5_DANRE", "id": "A0A8M9PMC5-1", "name": "Actin filament-associated protein 1", "aln": "MRSDPILFASRAMEELLAELRVFLELLDREYLTAGVREKKQQILNILHRVLATR-----EPSCKTEIHTSLPAPPQMPLPEIPHPWMPPDNGPPPLPSSSLPEGYYEEAVPLGPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGQKMRHQWPSEEASMDLVKDARICAFLLRKKRFGQWTKLLCVIKDNKLLCYKSSKDQTPQMELLLSGCSITHIPKDGKKKKHELKIVHQGADALVLAVQSKEQAEQWLKVMKEVCSNGNGVVDCDGAGSGST---VHKAELEKKLSCDRPSSDGEPCHENGIS--DGKDSAKGKKNSKSEQKGTVGRVTGKKITKIISLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNNRWRERWCQLKDNQLFLHKDRADLKTHMASLPLRGCEVIPGLDSKHPFAFRLLRNGQEVAVLEASSSESMGRWLGVLLAETGSTTDPAALHYDYIDVETTANVIQLAKQSFCFTSKRAVSPNPYLDNPVNGYACPTGVALHYDDVPCINGTIPDAHYSSPASGGRRWKDESHYENTDLYENMPSPKLAARYSPKSTRTSSSSGHYSTPNSTKSLSSSSAANTNTNQMKGKKGLIANGFGAKKLDKNQPKKANGISSTLPVKRNNSSVDQYKYGKNRVEADAKKLQAKEEELMRKKQEIRNRLTQLKKDRKDLRTALENNTAKRSQASLTERLKKVEDECKLKEEERVSLELELTEVKESLKKALNGGVTLGLTIEPKTGSSSPQSPVLMRRTVDNSPISSCNTSDTETCSLPVNSASLLRR-QTQQKASPVRGHVLRKAKEWEMKSGT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****:.***:******:****: ***** : *** *: ::: : : * * . *************:**:***.******:**************.**************:**.***************:* :** ***********:***********************.*********** ***** *.**.**:**:*.*********.:**:*.*****************:**. *. .* ** : . . *: *:*********.:******* ***:: :**:..* ** **** ****.:**********.******************************.*******::**.:*::****:*****:.*:****************::*******************.****:*:*******:*** ********** :*.*** ***:*** .:*.:*..***.. **** *:*.*********:**:: . : . .:.* . . :: ** * **.: . ***. *.. **************:**:*****:::*: :****:**:*:*****:*:* *:.::.*. * ::**::*:**: :* ******************** *******:***::*:*******: :**::*******:***:* .:*****::*:: *. :** *****:**:***:*.**", "identical_positions": 507, "similar_positions": 149, "identity": "61.75%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100316-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q07174-1", "uniprot_id": "M3K8_MOUSE", "id": "Q07174-1", "name": "Mitogen-activated protein kinase kinase kinase 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEYMSTGSDEKEE--------IDLLIKHLNVSEVIDIMENLYASEEPGVYEPSLMTMYP--DSNQNEERSESLLRSGQEVPWLSSVRYG---------TVEDLLAFANHVSNMTKHFYGRRPQECGILLN-MVISPQN------------GRYQIDSDVLLVPWKLTYRNIGS-------------------------------------------------------------------------------------------------GFVPRGAFGKVYLAQDMKTKKRMACKLIPIDQFKP-------------SDVEIQACFRHENIAELYGAVLWGDTVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKHILKGLDFLHSKKVIHHDIKPSNIVFMS-TKAVLVDFGLSVKMTEDVYLP-KDLRGTEIYMSPEVILCRG-HSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQAPPL-EDIAGDCSPGMRELIEAALERNPNHRPKAADLLKHEALNPPREDQPRCQSLDSALFERKRLLSRKELQLPENIADSSCTGSTEESEVLRRQRSLYIDLGALAGYFNIVRGPPTLEYG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63562-1", "uniprot_id": "M3K8_RAT", "id": "Q63562-1", "name": "Mitogen-activated protein kinase kinase kinase 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEYMSTGSDEKEE--------IDLLINHLNVSEVLDIMENLYASEEPAVYEPSLMTMCP--DSNQNKEHSESLLRSGQEVPWLSSVRYG---------TVEDLLAFANHISNTTKHFYRCRPQESGILLN-MVISPQN------------GRYQIDSDVLLVPWKLTYRSIGS-------------------------------------------------------------------------------------------------GFVPRGAFGKVYLAQDMKTKKRMACKLIPVDQFKP-------------SDVEIQACFRHENIAELYGAVLWGDTVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKHVLKGLDFLHSKKVIHHDIKPSNIVFMS-TKAVLVDFGLSVQMTEDVYLP-KDLRGTEIYMSPEVILCRG-HSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQAPPL-EDIAGDCSPGMRELIEAALERNPNHRPKAADLLKHEALNPPREDQPRCQSLDSALFDRKRLLSRKELELPENIADSSCTGSTEESEVLRRQRSLYIDLGALAGYFNIVRGPPTLEYG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41279-1", "uniprot_id": "M3K8_HUMAN", "id": "P41279-1", "name": "Mitogen-activated protein kinase kinase kinase 8", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEYMSTGSDNKEE--------IDLLIKHLNVSDVIDIMENLYASEEPAVYEPSLMTMCQ--DSNQNDERSKSLLLSGQEVPWLSSVRYG---------TVEDLLAFANHISNTAKHFYGQRPQESGILLN-MVITPQN------------GRYQIDSDVLLIPWKLTYRNIGS-------------------------------------------------------------------------------------------------DFIPRGAFGKVYLAQDIKTKKRMACKLIPVDQFKP-------------SDVEIQACFRHENIAELYGAVLWGETVHLFMEAGEGGSVLEKLESCGPMREFEIIWVTKHVLKGLDFLHSKKVIHHDIKPSNIVFMS-TKAVLVDFGLSVQMTEDVYFP-KDLRGTEIYMSPEVILCRG-HSTKADIYSLGATLIHMQTGTPPWVKRYPRSAYPSYLYIIHKQAPPL-EDIADDCSPGMRELIEASLERNPNHRPRAADLLKHEALNPPREDQPRCQSLDSALLERKRLLSRKELELPENIADSSCTGSTEESEMLKRQRSLYIDLGALAGYFNLVRGPPTLEYG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QJ64-1", "uniprot_id": "A0A8M9QJ64_DANRE", "id": "A0A8M9QJ64-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRPAVNTLTERMEYD-NGNSCIELLLAHIKIEDFIQEAEHFYSVGEVVESGISFEEGFSQEEMDENEETAHDLIKHVQKT---GKVRYG---------TTSDLLDFVNMVSNTPSSSLLDVGREMGVLVNKTDMIIKE------------GHYRIDLDVLLFPWKLTYKPQGP-------------------------------------------------------------------------------------------------GHVPKGSFGKVHLAQDTKTRKRMACKLIPVEHFKP-------------ADVEIQARFRHENIAELYGALLWEQTVHLFMEAGEGGSVLEKLESCGPMREFEIIWVSQQVLRGLEYLHSHNIIHHDIKPSNIVLMS-AKAVLVDFGLTVQMKDDVYVP-RDLRGTEMYMSPELVLCRG-HNTKTDIYSLGTTIIHMMSGSPPWVRRYPRTAYPSYLYIIHKQAPPL-EDIPQSCSPAMRRLLEHALERVPSQRSSATELLNEEALHPSREDQPRCWSLDSALEEGTHPLLRQYSQFSDSTQDSSLY--TEDSGHSKKKGSLYIDLGAFAGYYNLVRGPPSSEYG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q01389-1", "uniprot_id": "BCK1_YEAST", "id": "Q01389-1", "name": "Serine/threonine-protein kinase BCK1/SLK1/SSP31", "aln": "MPFLRKIAGTAHTHSRSDSNSSVKFGHQPTSSVASTKSSSKSPRATSRKSIYDDIRSQFPNLTPNSTSSQFYESTPVIEQSFNWTTDDHISAGTLENPTSFTNSSYKNDNGPSSLSDSRKSSGGNSVNSLSFDKLILSWDPTDPDEWTMHRVTSWFKFHDFPESWILFFKKHQLFGHRFIKLLAYDNFAVYEKYLPQTKTASYTRFQQLLKKTMTKNVTNSHIRQKSASKLKSSRSSSESIKSKLKNSKSQEDISNSRSTSESALSPTKSGPSKTDEKNFLHSTSTHQKTKSASSLYRRSFISLRGSSSSNASSAKSPSNIKLSIPARPHSIIESNSTLTKSASPPASPSYPSIFRRHHKSSSSESSLLNSLFGSGIGEEAPTKPNPQGHSLSSENLAKGKSKHYETNVSSPLKQSSLPTSDDKGNLWNKFKRKSQIGVPSPNTVAYVTSQETPSLKSNSSTATLTVQTADVNIPSPSSSPPPIPKTANRSLEVISTEDTPKISSTTASFKETYPDCINPDKTVPVPVNNQKYSVKNFLLDQKFYPLKKTGLNDSENKYILVTKDNVSFVPLNLKSVAKLSSFKESALTKLGINHKNVTFHMTDFDCDIGAAIPDDTLEFLKKSLFLNTSGKIYIKDQMKLQQKPKPAPLTSENNVPLKSVKSKSSMRSGTSSLIASTDDVSIVTSSSDITSFDEHASGSGRRYPQTPSYYYDRVSNTNPTEELNYWNIKEVLSHEENAPKMVFKTSPKLELNLPDKGSKLNIPTPITENESKSSFQVLRKDEGTEIDFNHRRESPYTKPELAPKREAPKPPANTSPQRTLSTSKQNKPIRLVRASTKISRSKRSKPLPPQLLSSPIEASSSSPDSLTSSYTPASTHVLIPQPYKGANDVMRRLKTDQDSTSTSPSLKMKQKVNRSNSTVSTSNSIFYSPSPLLKRGNSKRVVSSTSAADIFEENDITFADAPPMFDSDDSDDDSSSSDDIIWSKKKTAPETNNENKKDEKSDNSSTHSDEIFYDSQTQDKMERKMTFRPSPEVVYQNLEKFFPRANLDKPITEGIASPTSPKSLDSLLSPKNVASSRTEPSTPSRPVPPDSSYEFIQDGLNGKNKPLNQAKTPKRTKTIRTIAHEASLARKNSVKLKRQNTKMWGTRMVEVTENHMVSINKAKNSKGEYKEFAWMKGEMIGKGSFGAVYLCLNVTTGEMMAVKQVEVPKYSSQNEAILSTVEALRSEVSTLKDLDHLNIVQYLGFENKNNIYSLFLEYVAGGSVGSLIRMYGRFDEPLIKHLTTQVLKGLAYLHSKGILHRDMKADNLLLDQDGICKISDFGISRKSKDIYSNSDMTMRGTVFWMAPEMVDTKQGYSAKVDIWSLGCIVLEMFAGKRPWSN--LEVVAAMFKIGKSKSAPPIPEDTLPLISQIGRNFLDACFEINPEKRPTANELLSHPFSEVNETFNFKSTRLAKFIKSNDKLNSSKLRITSQENKTE-----------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. . . . . *: : : . .:. . * . : :::.. :..:: ::. . . * .* : : . .: . : * : : . * ** * ::: . : :*:** *:*. : .* : ** * : : ::.. ::*. : * **.: * : **:* **** . :. * : * * :: ::*:** :***: ::*:*:*..*::: . . : ***:: : .: . :*** ::*:**:: : :.:*.**:*** ::.* :*. ** . . . . : *.***: ** * *.::: .:* *.:*. * :**.. . . : :. * . : . : : .:. . ", "identical_positions": 78, "similar_positions": 146, "identity": "5.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100316-9", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LHQ8-1", "uniprot_id": "A0ABK0LHQ8_RAT", "id": "A0ABK0LHQ8-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MMKKEALLLIPNVLKVFLENGQIKSFTFDGRTTVKDVMATLQDRLSLRYIEHFALVLEYTGPEQNHKFLILQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRNDVIRERFGMDPKPEMLLGLAALHIYITVSATRPSQKITLKNVEKEWGLEPFLPPSLLQGIKEKNLRKSLSQQLKAHQMHPSSSTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSATTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDAKPLVLLMEWPEATNFACLIAGYCRLLLDSRKMIFSRPASQPLPPPMIKADHMHSAHRPVTGGHLGKKESSYVGSMGTSPRKSSRCTTPPADSELVSFCYLHMREQR------KEQESRTDVNENLIFFEETRPRTKSDPTSKSSGQGYEVIPDDFDATSLDHEPCASRARSYTLDNSLGAEALNFYCDSCKVKLQEQMGPRKGGRPG-----------SSRDN-MVDLMSLPPPGSEEEEEEEDETTSLLP----AIAAPPPGFRDNSSDEDDPKRRAVQSQEQGRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP--PPQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLARKDLPFRIQGCAAQAVLTAPYALGPPDPNPSLQPAVTGQSPAPAGARRKIPQSEAQVQGDRTYSLAVHPALSPQLSEQKNLSLLPPVPEDRGPGHSRAGLEMSLRSATPSLSEEQVSELRENLPKEVRLSPKLILDPKGSVTPAIISAALQQVVHSKSLATPGTALATPSNRGERRLEASMVRPEVTMGRPEV---SSSASKNLKFKMSPGALETTRNSQQQLGPEVSASPRASTGSRGDNLHLSLQEDRFPVQSFPPKSYLSRMSRDSMGKQATGDVAGKGGPEGAKPPPNKQSTVSGQGEKGQLESISKSSKLEEASLLPRAGYPMALQSPSCQSRSHSPSCQPRGPSPSSQSRGQSPSCQPRSQSPLRPLATSRQVSTMPSRKLETTLDGAHSASEGPTKPKSSRGP--FRLRNLFSATFPTRQKKETDERQAQLQKVKQYELEFLEELLKP-PSQGELPGTEYLQPPAPGRCSCQLRSSPVQQGPGMSREQRRSCDCKRICRGGR-PQAAQTPAPGLR--ERER------VAPTQRQPEAGPGLSLNSPINIQRIRSTSLESRECRSDPESGVSCLSTCASGGECLGDPNYRKLMRHYSISELDQGDTVSLTSDVYPHPPLGMLPREVKEIESGLPLGLGPKAKCAESPTLGEPSYVQVAPESKGPRQMAVFSLPEEVYRRPADLDEDSESSKCCSIRYCFYYRKCDMADDASDGKDELSYSIPMKILPGMKLDEQVVPVVSRTLQVLDAATCSSS----PEAPHTQEIDLRVS-TFEGSLAKINALRAHAYGLPDGFLAARLDTNELLTVLRQCVASPEAR--APKPYVSQISEYKLELALKFKELRASCRRVANVDKSPTHMLAAITGSFQVLSSLIETFVRLVFIVRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQ-QQQQQQQQQQQQQPLPP------PPLPAATG-HPPGSP-SSTVMSTFSRSLKTLIK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A140LIW3-1", "uniprot_id": "A0A140LIW3_MOUSE", "id": "A0A140LIW3-1", "name": "", "aln": "----------------MQEESANDMECVQLPAETLRQVTIHRDPIYGFGFVAGSERPVVVRSVRPGGPSEDKLLAGDQIVAINEEDVSEAPRERFIELIRSAKESIVLTVLHTHQSPKSAFISAAKKAKLRSNPVKVRFSEQVTIGETDAKMMKKEALLLIPNVLKVFLENGQIKSFTFDGRTTVKDVMATLQDRLSLRSIEHFALVLEYTGPEQNHKFLILQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRNDVIRERFGMEPKPEMLLGLAALHIYITVSATRPSQKITLKNVEKEWGLEPFLPPSLLQGIKEKNLRKSLSQQLKAHQMHPSSSTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKHSATTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDAKPLVLLMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADHMHSAHRPVTGGHLGKKESSYVGSVGTSPRKSSRCTTPPADSELVSFCYLHMREQR------KEQESRTDVNENLIFFEETRPRTKSDPTSKSSGQGYEVIPDDFDAASLDHEPCASRARSYTLDNSLGAEALNFYCDSCKVKLQEQMGPRKGGRPG-----------SSRDN-MVDLMSLPPPGSEEEEEEEDETTSLLP----AIAAPPPGFRDNSSDEDDPKRRAVQSQEQGRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP--PPQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLARKDLPFRIQSCAAQAVLTAPYALGPPDPNPSPQPAVTGQSPAPTGARRKIPQSEVQVQGDRPYSLAVHPALSPQLSEQKNLSLLPPVPEDRGPGHSRAGLEMSLRSATPSLSEEQVSELRENLPKEVRLSPKLILDPKGNVTPAIISAALQQVVHSKSLATPGTALATPSNRGERRLEASMGRPEVTMSRPEVSVMSSSVSKNLKFKMSPGAPETTRNSQQQLGPEVSASPRASTGSRADNLHLSPPEDRFPVQSFPPKSYLSRVSRDSMGKQATGEVAGKGGPEGAKPPPNKQSVVSGQGDKGQLESLSKSSKLEETSLVPRAGYPMALQSPSCQPRSHSPSCQPRGPSPSSQSRGQSPSCQPRSQSPLRPLATSRQVSTMPSRKLETTLDGAHSASEGPTKPKSSRGP--FRLRNLFSATFPTRQKKETDERQAQLQKVKQYELEFLEELLKP-PSQGELPGTEYLQPPAPGRCSCQLRSSPVQQGPGMSREQRRSCDCKRICRGGR-PQAAQTPAPGLR--ERER------VPPTQRQPEAGPGLSLNSPINVQRIRSTSLESRECRSDPESGVSCLTTCASGGECLGDPNYRKLMRHYSISELDQGDTVSLTSDVYPHPPLGMLPREVKEIESGFPVGLGPKSKCAESPTLGEPSYVQVAPESKGPRQMAVFSLPEEVYRRPADLDEDSESSKCCSIRYCFYYRKCDMADDASDGKDELSYSIPMKILPGMKLDEQVVPVVSRTLQVLDAATCSSS----PEVPHTQEIDLRVS-TFEGSLAKINALRAHAYGLPDGFLAARLDTNELLTVLRQCVASPEAR--APKPYVSQISEYKLELALKFKELRASCRRVANVDKSPTHMLAAITGSFQVLSSLIETFVRLVFIVRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQLQQQQQQQQQQQQQPLPP------PPLPAATGHHPPDSP-SSTVMSTFTRSLKTLIK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JV73-1", "uniprot_id": "FRPD3_HUMAN", "id": "Q5JV73-1", "name": "FERM and PDZ domain-containing protein 3", "aln": "----------------MQEESANDMECEQLPAEILRQVTVHRDPIYGFGFVAGSERPVVVRSVRPGGPSENKLLAGDQIVAINEEDVSEAPRERLIELIRSAKEFIVLTVLHTHQSPKSAFISAAKKAKLRSNPVKVRFSEQVAVGETDAKMMKKEALLLIPNVLKVFLENGQIKSFTFDGRTTVKDVMLTLQDRLSLRFIEHFALVLEYAGPEQNHKFLLLQDKQPLAYVVQRTHYHGMKCLFRISFFPKDPVELLRRDPAAFEYLYIQSRNDVIRERFGMDPKPEMLLGLAALHIYITVSATRPSQKISLKNVEKEWGLEPFLPPSLLQVIKEKNLRKSLSQQLKAHQTHPSCGTKGSAIQAKLQYLRILNELPTFTGVLFNTVGLDEKQSATTLLVGPRHGISHVIDLKTNLTTVLSEFSKISKIQLFRENQGVARVETSIMDAKPLVLLMEWPEATNFACLIAGYCRLLLDSRKMVFSRPASQPLPPPMIKADYMHSAHRPVTGGHLGKKESSYVGSVGTSPRKSSRCTPPPADSELVSFCYLHMREQR------KEQESRTDVNENLIFFEETRPRTKSDPTSKSSGQGYEVVPDDFDAASLDHEPCASRARSYTLDNSLGAEALNFYCDSCKAKLQEQLGPRKGGKPG-----------SSRDN-IVDLMSLPPPGSEEEEEEEDETTSLLP----AIAAPPPGFRDNSSDEDDPKRRAVQSQEQGRHLRGLLYDEIPVTLIDSVQTRTVRDHAQELDDALVSTLQALEALAASEDGPHPP--PPQTAGLIVLATITPESSLDSGHETNSSELTDMSEMMSAMKQHQNTTYFLAQHLNKDSLLARKDLPFRIQSCAAQAVLTAPYSLGRPDPNPSLQPIATGQSPGPPGARRKLPQSEGQVQGERTYSLAVHPALSPQLSEQKNLSLLSPVPEDKGPGHTRAGLEMSLRAATSSLSEEQVSELRDNLPKEVRLSPKLILDPKSSVTPAIISAALQQVVHNKSLVTAGGALGNPPSRGERRLEASMGRPEVSMM-------SSSASKNLKFKISPSAPETSWNSQHQLGAEVSSSPRAPTGSRADSLHLSQQEDSLPVQNFPPKSYLLRTSRESVGKQATGEVAGKGGPVGGKPTLQKQGTISSQGEKAQLESTPKRSKLEETSLVPRATYPMALQSPSCQSRSHSPSCQPHGHSPSSQSRGQSPSCQPRGQSPLRSQAASRQVSTMPSRKLETTLNGAHSTSEGPAKPKSSRGP--FRLRNLFSATFPTRQKKETDERQAQLQKVKQYELEFLEELLKP-PSQGELPGTEYLQPPAPGRCSCQLRSSPVQQGPGMSREQRRSCDCKRICRGGR-PQATQTPVPSLRGRERDR------VLPSQRQPEAGPGVSLSSPINVQRIRSTSLESRECRSDPESGVSCLTTCASGGECLGAPNYRKLMRRYSISELDQGDRASLTSDVYPHPPLGMLPREAKEVEASLPIALGPKSRSLESPTLGDPSYVQVAPETKGPRQMAVFSLPEEVYRKPAELDEDSESSKCCSIRYCFYYRKCDMADDASDGKDELSYSIPMKILPGMKLDEQVVPVVSRTLQVLDAATCSSSS---PEASRTQEIDLRVS-TFEGSLAKINALRAHAYGLPDGFLAARLDTNELLTVLRQCVASPEAR--APKPYVSQISEYKLELALKFKELRASCRRVANVDKSPTHMLAAITGSFQVLSSLIETFVRLVFIVRSEAQRQELLAKVEEVVRNYTFLLRAAEESTARNLNQQQQQQQQQQQQQQQQQQQQQQQQQQQVAAAAGAATEHPPGSPTSATVMSTFTHSLKTLIK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QKJ4-1", "uniprot_id": "F1QKJ4_DANRE", "id": "F1QKJ4-1", "name": "", "aln": "MARVQDGHTEEYDSSVMLEDGQDGMDSDSLTPGLTREVCIQRHPSHGFGFIAGSERPVVVRSVSADGPSSGKLYPGDQILAINQELVSDVPREKVIDLVRCCRDSIVLTVLQPQQSPKSAFISAAKKARLRTNPPKVRFSEQVSISDPDSTMLKDDSLLLIPNVLKVFLENGQIKSFTFDSRTTVRDVISSLQDRLSLRYIEHFALVLESGGLAQNQRLHLLQENQPLSHVVHRTYFQGMKCLFRICFFPKDPSDLLRRDPAAFEYLYIQSRNDVIKERFGMDWKFDVTLRLAALHIYITVSIARPNQKISLKHVEKEWGLEPFLPLALLPTIKEKNVCKTLSQLLKTYQHPPPAGNKVSPLQGKLQYMRVLNDLPPFGGFLFHTVGLDEKQSATTLLVGPRHGISHVIDLKNNLTTVLAEFSRVAKVQLFREHHGVARVEVVILDAKPLVLLMEWPDASNFACLISGYYKLFVDPKRTIYCRIPGQ---PYVIKADCRSSHAQTRSGATVLS--GSAREERETSSRETTQKTSASPIPQHLGLCHIHLKEQQQLQEFQIQAEQELDVNENLISQVQSRSRTKSDPTLKST----ESVAEHDGPT---EESSSFRNRAKTLEPSQ-----KFFCEFCKAKLQAEGIIQKTGETGRLILQQCTNACSSREGGAVDLIALPLPGNEEDEEIEDGGGKLQPPTHAAIAAPPPGFRDNSSDEDDPKKGRKGIKASTAVAQGQ--DEVPVTLIDNVTTRTVQDHAQELDDALVSTLQALEALAASEDYPHHQQQTPQTTGLIVLAAITPESSLDSGHETNSSELTDVSEMVSAMKQHQNQAYLLAHHINKERLFSRRDFPLTIPGCTTQAIGGGAFSMSQIRGSCPPKPVILS----------------------KTLPLKISPNKEISHSDK---------SAEWGKSHEANG-EKDIEITEKGLVTECLEESKLQISEELKA-------PEHGSAPQVNTELLLANEEKPSTITSEGAQEEDS--CAKTLETTSIALPVLLP----------VDRTTSAKICS----TNRCQDAKNASSETTKPSSSKG-------LLPTADLFCTCPIRPEPGPQVRLKD---PQVQKLVVFHS------LSPTDDERLHAKGLQLAKEDTAKTS---DASLVTPNTLPSTKYSPVMSAKVEKKEMS-EAKAENSQSK-SPVEIQKVAKSLPVNVDPTHMLSCVEKG---ATIPGAEYKKQANNKGKSQRSTPFLSFRNLISATFPARLRRETDERRAQLQKVRQYELEFLEELLKPKTSQGEFLPQGSSPVPSFTPCACQLRTSPVQKVPGISREQRRSCDCKRMCRGMRLPDTAVGSATEQRGRERAISKTPPAIPKSPHTPQGELQKNQTLEIKTTRIRSTSLESREPRDIP---TSCLPMCTTRTESIGAPHYKKLQRRYSIGEIENNGSTPLYAEVKTTKAKSLEKEMERVRATGLRLPTPVEPVHTKDGDAKKIFYIQGEEILQESR-----EGTAEVLGLPSEDTEDRE--KCCS--FCFCYRKCEAADESSE-KDELSYSIPLQVLPGMHLDSRTMPVISKTLQVLDAEDCCGEEEVQEEEPQTQRIDLRVCGNLEASLARVKSLQDKTFSLPDGFLNAQLDANELLSILRQCANSPQIEG-EPRIPSATLAEYKQELAVRFKEFRASCRRVASVEKSPSRMLSAVTASFQVLCNLTQTFIQLVRGVRSETQKLQLLRKVEEVAVNYTLLLRAAEEAMGHSSSLPNKTASPQVHISIN---------------------------------MGSLNRSIKTLPSK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFD3-1", "uniprot_id": "Q9VFD3_DROME", "id": "Q9VFD3-1", "name": "FERM and PDZ domain-containing protein 4", "aln": "--------------MMLLPSGRSNSDVYPLQNAANTTATSTGGATSAGGAGGAGGVGGVCGGVGATSNPKPLLLTR-----TSSPQLTTLPTTNGSVVHATPTRSNGCPLTQSSGIPVTMATTATAMATATPDPSGCTEVEGTASTELSTGLANETNCGTGIYGPLLGQSHGGVIAGMTENWPEIDGHLEAIQEKLKPGWSVHVGKEGR-----LYYCNHMTQSAGWLPACEDWSKHEELSYGWERAIDSKGRSYYINHLNKTTTYEAPECIR---WDEHPPEPRQVQLQRNASLGFGFVAGSERP--VIVRFVTEGGPSIGKLQPGDQILAVNGEDVKDAPRDHVIQLVRACESQVNLLVCQPMAHCV-----LPGRKSTLLSAGKRAKLRSRPSRVRFAESVCVNGAPLFPPSAFSLGDICVPPMANVLKVFLENGQTKSFKYDATTTVQDVVSSLLDKLCLCCGELFSLVLEHVKSLKR--------NKLTLLDPQESLARIAARPGAHKLRCLFRITFVPISAAELAQRDLHALDYLYLQCCNDVNQER------FAPELQPELALRLAALHMHQHALANN-----------FAPAKLTVKLVEREFGLERFVPVSLFEGMKRKELRRLISHFLKLNAEMTGSSSKVLTQ----------LQAKLHYLDIIASLPSYGAKCFSTNQREGVERVL-----LVSPRFGLSQISSARNSVQPQ-------------------PISAIEDFTHVVVNREDDVTCSVSIFMLGDRAVKFIMED----------RDGCEFSLVLGGYYRLLTGNVLNILREREP-------NDEDNAPGFLSQHTVLPAGWS-YLLPFHTRAHSVNFLMAPPYHPLVQRGQLQQQSSIQAPSSLP-----------------YVMDLDLHSVMATELLEEA--------AKDSGLSDSSGSNYCEGRSHLGSHQLEAKNE-----------------------------QVLRRVQELQHLVQTSEQYLSEQEQGGGGGGVAMLEF-------------------------------DSDCDSLNSSKVSSTEGSQGG------TILGPGAIIPPGHPLKHSDSLTLLAETINHELSGITQGLN-------AIPESAPVSTSAPPTPATPKRKPSLCSTSSPRPQRKLNGFSQLLSDLQALGTDFSQSESDSESVASPAQSPTTRRPQMMLLQAAGSSAGSVAPAKQQLSQRSSFGLHSPDGTHFGAETKDY---NLREYLQQLKEISNAASADTDVAARQLSEIYGFEVREDTFIE--TDTDLIDLRAIPPPQTPDELDSLSLMNAAPPKGFEGKAEELDSFLQQIMVAP-PTQKATPAKELTPEEIMS--------FIIPPPPNLEQQQVVAPVETECLYSNSVQAK--REFFQSVANGNNGTVSHSPHIIEYATVERKSKFSCCPTSKKEEQPGQEELQPPP-----RTPTTEQLSPPPARPPKSAELLQRYSPKKQVRIAASPVMQPQERRELCPPQLPPRGSPTLDGSQSSPTNAVS-----GPKKPPLPPIACRPRPSNGVNSPNSSSPGSAPPAHYSPPIPATVRLPHLNQANGTLPLLPKKP--QQLHGEKLFIKNGHLIDGEALLAKTDVAMSGLLIKLDQVAAQCSVAQAAGGGTSIDEEKFQRARNELTEQTLALVTASKFLVASMS-----DMTLITLPEHLTSCLTAIRRITELAQDMTRHTSAPLQTRNIVLKVHDVASSFRELVGVEIGPIGAGQLALQAECLAN--------------------------------------VLATLLRSLRVFSP-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. : .:* : : :. . : . : ::*::*. *.. . : *. *. . : .. :. :. .: .*. :.: : * :. . :.. : : *:* : :... ** * .* .: : * : :: ::: .: : : . : * : : ** . *: : : :* .: : .. : * : *.::. . :::: .:.: **.. * : . ::. . *.:: : : : * * : : . . . . * .:.::: * . :: .* : .: . . .* * . :* . . . . . .:: : :** * : . : . :.:* *: : ** .:. : *:: *:.. .*. . : .. : * . ** * . .: * :*: * . : ::.:* . :*::* : :*: . :.: : .: . :. . * : . . :: . : * .. . . . . * .* * . . .: : ... ::. : * : : .. : : . . . .. : .. * * :* . . . .. : . * .. : .: . . :. . :. :*: :. .:* * * . * :*. *: : :: :: * .* . *:. : .. . : * .. * * . :: : *.*:::: *. .. .: : : ::* .: . :: . : .. : . : : . *: .: . :. * :* . :. : . . . * . ** : * :. *::: . . . : . *.:. . :. * ::* :: .*:* :. :: : . ... : ::* . *. * : ** : : : :*..: .: : : :. . : * ::: **.:*. .: *: . . . . : : :.:: :*::.: ", "identical_positions": 107, "similar_positions": 411, "identity": "5.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100318-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZSJ9-1", "uniprot_id": "A0A8I5ZSJ9_RAT", "id": "A0A8I5ZSJ9-1", "name": "Actin filament-associated protein 1-like 2", "aln": "MKVIPSEYWASQATITPLANGSPVTPFEVVCLKFKALEQLLTELDDFLKVLDQENLSSAAVVKKSGLSELLRLYTKSSSS-DEEYIYMNKVAVNKE-QNPASPDKVPEEKQGPLTNGEPSQHTSAPQKSLPDLPPPK-MIPERKQPTIPKIESP-----EGYYEEAEPFD-TSIN----------------------------EDGEAVSSSYESYDEEESSKGK-TAPYQWPSPEASIELMRDARICAFLWRKKWLGQWAKQLCVIRDTRLLCYKSSKDHSPQLDVNLLGSSVVHKEKQVRKKEHKLKIMPMNADVIVLGLQSKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRLNCQKPDIAEKYMSASEYGITTDGHPEIPETRDVKKKCSAGLKLSNLMNLGRKKSTSLEPPDRSLETSSYLNVLVNSQWKSRWCFVRDSHLHFYQDRNRGKMAQQPLSLVGCDVLPDPSPDHLYSFRILHNGEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEELTYDYVDAERVSCIVSAAKTSLLLMQRKFSEPNTYIDGLPSR-DCQEELYDDVEMSELMAAVEPAEEATLAGDATPAVDANSGSDLDRVYLDLTPVKSFLHNTS---------EVQVQASLPAVPHLDDVAETLTVDPKPGTTPE-------EPCTESPG----GQEMQQRQPEGQEPSEPIEPTPRVTTVKLQAEQQRISFPANCPDTMASVPISASPPVKDKLRVT------SAEIKLGKNRTEAEVKRYTEEKRRLERSKEEIRGHLAQLRREKRELKETLLRCTDKGVVAKLEQALKRIDEECRLEESRRVDLELSIVEVKDNLKKAEAGPVTLGTTVDTTHLDN--------MSPRPQPKAATPTSTPDST-----PVNSASVLKNRPLSVMVTGKGTVLQKAKEWEKKGAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5DTU0-1", "uniprot_id": "AF1L2_MOUSE", "id": "Q5DTU0-1", "name": "Actin filament-associated protein 1-like 2", "aln": "------------------------------MERYKALEQLLTELDDFLKVLDQENLSSAAVLKKSGLSELLRLYTKSSSS-DEEYIYMNKVSVNGE-QNSASPDKVPEE-QGPLTNGEPSQHSSAPQKSLPDLPPPK-MIPERKQPTVPKIESP-----EGYYEEAEPFD-RSIN----------------------------EDGEAVSSSYESYDEDENSKGK-AAPYQWPSPEASIELMRDARICAFLWRKKWLGQWAKQLCVIRDTRLLCYKSSKDHSPQLDVNLRGSSVVHKEKQVRKKGHKLKITPMNADVIVLGLQSKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRLNCQKPDIAEKYLSAAEYGITINGHPEIPETKDVKKKCSAGLKLSNLMNLGRKKSTSLEPPERSLETSSYLNVLVNSQWKSRWCFVRDSHLHFYQDRNRSKVAQQPLSLVGCDVLPDPSPDHLYSFRILHNGEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEELTYDYVDAERVSCIVSAAKTSLLLMQRKFSEPNTYIDGLPSR-DCQDDLYDDVEVSELIAVVEPAEEA------APAVDANSGSEPDRVYLDLTPVKSFLHSSS---------EAQAQASLPAVPHQDDVAETLTVDPKPGTTPE-------EPHTESPG----DPEVQQRQPEVQESSEPIEPTPRITMVKLQAEQQRISFPANCPDTMASAPIAASPPVKEKLRVT------SAEIKLGKNRTEAEVKRYTEEKERLERSKEEIRGHLAQLRREKRELKETLLRCTDKGVLAKLEQTLKKIDEECRMEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVDTTHLDN--------MSPRPQPKAATPNPPPDST-----PVNSASVLKNRPLSVMVTGKGTVLQKAKEWEKKGAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N4X5-1", "uniprot_id": "AF1L2_HUMAN", "id": "Q8N4X5-1", "name": "Actin filament-associated protein 1-like 2", "aln": "------------------------------MERYKALEQLLTELDDFLKILDQENLSSTALVKKSCLAELLRLYTKSSSS-DEEYIYMNKVTINKQ-QNAESQGKAPEE-QGLLPNGEPSQHSSAPQKSLPDLPPPK-MIPERKQLAIPKTESP-----EGYYEEAEPYD-TSLN----------------------------EDGEAVSSSYESYDEEDGSKGK-SAPYQWPSPEAGIELMRDARICAFLWRKKWLGQWAKQLCVIKDNRLLCYKSSKDHSPQLDVNLLGSSVIHKEKQVRKKEHKLKITPMNADVIVLGLQSKDQAEQWLRVIQEVSGLPSEGASEGNQYTPDAQRFNCQKPDIAEKYLSASEYGSSVDGHPEVPETKDVKKKCSAGLKLSNLMNLGRKKSTSLEPVERSLETSSYLNVLVNSQWKSRWCSVRDNHLHFYQDRNRSKVAQQPLSLVGCEVVPDPSPDHLYSFRILHKGEELAKLEAKSSEEMGHWLGLLLSESGSKTDPEEFTYDYVDADRVSCIVSAAKNSLLLMQRKFSEPNTYIDGLPSQ-DRQEELYDDVDLSELTAAVEPTEEA------TPVADDPNERESDRVYLDLTPVKSFLHGPS---------SAQAQASSPTLSCLDNATEALPADSGPGPTPD-------EPCIKCPE----NLGEQQ-----LESLEPEDPSLRITTVKIQTEQQRISFPPSCPDAVVATPPGASPPVKDRLRVT------SAEIKLGKNRTEAEVKRYTEEKERLEKKKEEIRGHLAQLRKEKRELKETLLKCTDKEVLASLEQKLKEIDEECRGEESRRVDLELSIMEVKDNLKKAEAGPVTLGTTVDTTHLEN--------VSPRP--KAVTPASAPDCT-----PVNSATTLKNRPLSVVVTGKGTVLQKAKEWEKKGAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QN06-1", "uniprot_id": "A0A8M9QN06_DANRE", "id": "A0A8M9QN06-1", "name": "Actin filament-associated protein 1-like 2", "aln": "------------------------------MDKHKVLEQLLEQLQKFLKILDVEKLSGNAKVQKGLLMELLQSYKSSNAGGDEEYIYMNKVIVTCQTQDKTNRDHRPEA------NGDPSKHISV--KNPPEPPPPRPCNTGREPFPLPPAPAPASMENESYYEDPQPYDPISINDFGCFAVITGLRKRVEASNGVVYAVITREDTEQLSSSYESYDEEEVTKGKSTAQHQWPSPEASIELMKDARICAFLWRKKWLGQWAKQLCVVREHRLLCYKSSKDQTPLLDISLLGCSVVYKEKQTKRKEHKLKISPLGAEAIVLGLQSKEQAEQWLKVIQEISPKNTTGSD-----VTDSPTLICTKGEQSERYSVASESGSSTDSHAENMENKDVKKKYG---KFSNLMNIGKKKVCSLESPEKSVDTSGYLNVLVNTQWRSRWCSVKDRQLWIYSDKSKGKVAQQPLSLEGCMVLPDPSPEHLYSFRIQMDGEELAILEAKSSADMGHWLGLILSQTGTKTDPEDLSYDYVNSERISSIVNAAKTSMYLMQRRYSEPNTYTDSPPSDPQTCDDIYDDVPSTENEQEEVQEVQN---GSEEGTVNAEEENGKDRVYLDLIPLRSFLHTSSGRVSPQTSSTTQTEISPSTTPHVDDQLKEPVYESSLPTSTENEVPPPVAPRVDTDPSPVPNLHVQPQKISFLGQEIQKKASSTSPLPKTQSLPQTSAQTPQSPPTSRAR-AASTDRLLDRLKFSPAAGPGSVEVKLGKNRTEADVRRYTDDRDRLEREREEVKNTLATLRKDRREVKDELSSCQDPIRQASLEARLKQMEETCREAERRRVEVELSLMEVKENLRKVESGPFTLGTTVDSSLLEISVHKPAAVSSPAPNTPNNTNINTPACTNNGDSPVNSATALKNRPPSVMAASKGNVLQKAKEWEKKTTT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*.***** :*:.***:** *:**. * ::*. * ***: *..*.:. ********** :. : *: . .: ** **:**:* *. *. *: ***: . *: .:* :* *.***:.:*:* *:* ** * :*********:: :*** :* :*******.****:***********************::: **********::* **:.* *.**::****.::* ***** *:.*:.********:******:****:* : *:. ..*: : * * : :*:* *:* * : :.*.* *.:***** . *:*****:*:** ***. ::*::**.*******:**:**** *:* :* :*.*:.:.*:******* ** *:*****:******* .***** ****** :*******:**::*:*****:::****:::*:*.**.***.*: ****::****** *. ** : :::**** :* : ..: . ******* *::**** .* .*.: * .: . *: : :. .:.: * . . * ..: . * *: * : ....* : : .:: : ::*:.: *.*:*********:*:***::: ***:.:**::. ** **:::**:*: * * * *.** **.::* ** * ***::***::***:**:*.*:**.*******:: *: ** * * .* .* *****:.***** **:.:.**.*********** ::", "identical_positions": 401, "similar_positions": 225, "identity": "42.66%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100318-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZLM5-1", "uniprot_id": "D3ZLM5_RAT", "id": "D3ZLM5-1", "name": "NHL repeat-containing protein 2", "aln": "MAVPGARGASLSGLLPAQTSLEYALLDAVTQQEKDDLVYQYLQKVDGWEQDLAVPEFPEGLEWLNTEEPLSIYRDLCGKVVILDFFTYCCINCIHVLPDLHALERTFSDTDGLLIVGVHSAKFPNEKVLDNIKSAVLRYNITHPVVNDTDASLWQELEVSCWPTLVILGPRGNLLFSLIGEGHKDKLFSYTSIALKYYKDRGQIRDGKIGIKLFKESLPPSPLLFPGKVAADPTTGRLVVADTGHHRILVLQKNGQIQYSIGGPNPGRKDGVFSESSFHSPQGVAIADNVIYVADTENHLIRKIDLEAEKVSTVAGIGVQGTDTEGGEEGDKQPISSPWDVALGTSGSKVQRNDILWIAMAGTHQIWAFLLDSGTLPKKSDLKKGTCLRFAGSGNEENRNNAYPHKAGFAQPSGLALAPEEPWSCLFVADSESSTVRTVSLRDGAVKHLVGGERDPMNLFAFGDVDGAGISAKLQHPLGVAWDEKRHLLYVADSYNHKIKVVDPNTKVCTTLAGTGDANDASSS-FAESAFNEPGGLCIGERGRLLYVADTNNHQIKVMDLEARTVSVLPVFKSD--SAVVDGSFP-REKQKTVPKVPKSAPNISLPPVTVHPGQALQLGLRLELPPGAKLTEGAPSGWFLKAEGNEWLLQEQIPSGDIENISNQPAISLQIPTECLSLEAVVSVTVFLYYCSADSSACMMKGVVFRQPLQINSVQPACAAPVELTYAF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZW8-1", "uniprot_id": "NHLC2_MOUSE", "id": "Q8BZW8-1", "name": "NHL repeat-containing protein 2", "aln": "MAAPGARGASLSGLLPAQTSLEYALLDAVTQQEKDELVYQYLQKVDGWEQDLAVPEFPEGLEWLNTEEPLSIYKDLCGKVVVLDFFTYCCINCIHVLPDLHALERRFSDKDGLLIVGVHSAKFPNEKVLDNIKSAVLRYNITHPVVNDADASLWQELEVSCWPTLVILGPRGNLLFSLIGEGHRDKLFSYTSIALKYYKDRGQIRDGKIGIKLFKESLPPSPLLFPGKVAVDHATGRLVVADTGHHRILVIQKNGRIQSSIGGPNPGRKDGMFSESSFNSPQGVAIADNVIYVADTENHLIRKIDLEAEKVTTVAGVGIQGTDTEGGEEGDKQPISSPWDVALGTSGSEVQRNDILWIAMAGTHQIWALLLDSGTLPKKSDLKKGTCIRFAGSGNEENRNNAYPHKAGFAQPSGLALASEEPWSCLFVADSESSTVRTVSLRDGAVKHLVGGERDPMNLFAFGDVDGAGINAKLQHPLGVAWDEERQVLYVADSYNHKIKVVDPKTKGCTTLAGTGDASDASSS-FAESAFNEPGGLCIGESGRLLYVADTNNHQIKVMDLEARTVSVLPVCKSD--SAVVDGSFP-REKQKTVPKVPKSAAHIGLPPVTVHPGQALQLRLKLQLPPGAKLTEGAPSCWFLEAEGNEWLLQEQTPSGDIENISNQPAISLQIPTHCLSLEAVVSVVVFLYYCSADSSACMMKGVVFRQPLQITSTQPACAAPVELAYAF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NBF2-1", "uniprot_id": "NHLC2_HUMAN", "id": "Q8NBF2-1", "name": "NHL repeat-containing protein 2", "aln": "MAAPGGRGRSLSGLLPAQTSLEYALLDAVTQQEKDSLVYQYLQKVDGWEQDLSVPEFPEGLEWLNTEEPISVYKDLCGKIVVLDFFTYCCINCIHLLPDLHALEHTYSDKDGLLIIGVHSAKFPNEKVLDNIKSAVLRYNITHPMVNDADASLWQELEVSCWPTLVILGPRGNMLFSLIGEGHKDKLFLYTSIALKYYKDRGQIRDNKIGIKLYKDSLPPSPLLFPGKVTVDQVTDRLVIADTGHHRILVVWKNGQIQYSIGGPNPGRKDGIFSESTFNSPQGVAIMNNIIYVADTENHLIRKIDLEAEKVSTVAGIGIQGTDKEGGAKGEQQPISSPWDVVFGTSGSEVQRGDILWIAMAGTHQIWALLLDSGKLPKKNELTKGTCLRFAGSGNEENRNNAYPHKAGFAQPSGLSLASEDPWSCLFVADSESSTVRTVSLKDGAVKHLVGGERDPMNLFAFGDVDGVGINAKLQHPLGVTWDKKRNLLYVADSYNHKIKVVDPKTKNCTTLAGTGDTNNVTSSSFTESTFNEPGGLCIGENGELLYVADTNNHQIKVMDLETKMVSVLPIFRSE--NAVVDGPFL-VEKQKTLPKLPKSAPSIRLSPVTACAGQTLQFKLRLDLPSGSKLTEGVSSCWFLTAEGNEWLLQGQIAAGDIENISSQPTISLQIPDDCLSLEAIVSVSVFLYYCSADSSACMMKAILFSQPLQITDTQQGCIAPVELRYVF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QN08-1", "uniprot_id": "A0A8M9QN08_DANRE", "id": "A0A8M9QN08-1", "name": "NHL repeat-containing protein 2", "aln": "MASYS----KLTDLFLIQGQLDCDLEETTSQEEKEKLVHEYLLKIDERE-DLIVPDFEEGLEWLNTDGPLSLGKELLGKVVLLDFFTYCCINCIHILPDLHQLEKNYSIQDGLIVVGVHSAKFPNEKVLQNVQSAVLRYDINHPVVNDSDARLWQELEVSCWPTLLLLGPRGNLLFSLVGEGHREHLFLFTAAALKHYREQGLLKDHNVGIKLYRDSLPPSILSFPGKIAIDPSGKQLAIADTGHHRVLVVSNTGQVLHTVGGPSSGKRDGNLSEAQFSSPQGLFIKGDTVYVADTENHLVRKINLTEGKVSTLAGIGVQGTDKEGGALGPQQPISSPWDVTLGSAG-----GDVLWIAMAGTHQIWALFLEDGKLPKGSDSKAGTCVRFAGSGNEENRNNAYPHKAGLAQPSGLALAPTEPWESLFIADSESSTIRSLSLKDGAVKHVVGGERDPLNLFAFGDVDGKGIDAKLQHPLGVSWDEGRSLLYVADSYNHKIKVVDPKTKQCMVLAGTGEAGNGIGPRFLESSFNEPGGLCVGEGGKLLYVADTNNHHIKVLDLETKTVSLFPIVGHQDVDAILKTTTNNTSAVKKRPKLPKSAPVLAMPSISISSGQSVTLLLKLALPAGTKLTEEAPSFWSLSAEGNEWLLEGRAVTGSIDDLSEPISIVLSIPVAPVSPDPTLTLDAWLYFCVSEGGACMMKTVSFKQPLLISSTSQEGSVAITLKHAF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . .*:.*: * .*: * ::.:*:**:.**::** *:* * ** **:* ********: *:*: ::* **:*:*************:***** **: :* ***:::*************:*::******:*.**:***:** *************::******:****:****:::** :*: ***:*:::* ::* ::****:::***** * ****:: * :*.:*******:**: :.*:: ::***..*::** :**: * ****: * .: :*********:***:* **:*:**:*:****.*** * :*********.:*::* .*:*************::*:.*.*** .: . ***:********************:******:**. :**..**:*******:*::**:******:*******:********** **.*********:**: * :****************:** * .*****::.: .. * **:********:** *.**********:***:***:: **::*: : .*::. . . *. **:****. : :..:: .**:: : *:* **.*:**** ..* * * ********: : :*.*:::*. :* *.** :* :. ::: .:**:* ::..***** : * *** *.... ..: * :.*", "identical_positions": 413, "similar_positions": 197, "identity": "56.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100318-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C9S4-1", "uniprot_id": "CC186_MOUSE", "id": "Q8C9S4-1", "name": "Coiled-coil domain-containing protein 186", "aln": "-------MKIRSRFEEMQSELVPVSMSETEHIASISSDATTEKTSELRDDSCISVSGDESSRLETGAELLSLDSDRILCQ-TNEHC---------SQIEVQESHIPDCGSGENSCANTDTCPEDS--GQIDDFPGGDFTEQVS-----KTKEPEQTVTQILAELKSSAPAEAAN---------PKTASASLYDTDCTRKLISEMKTVSASDDLLGEIESELLS--AEFAEGHQVPNGLNKGEQALALFEKCVHSRYLQQELTVKQLIKENKNHQELILNICSEKDSLREELRKRTETEKQHMNTIKQLELRIEELNKEIKASKDQLVAQDVTAKNAIQQIHKEMAQRMDQANKKCEEARQEKEAMVMKYVRGEKEALDLRKEKETLERKLRDASKELEKNTNKIKQLSQEKGRLQQLYESKEGETTRLIREIEKLKEEMNSQVIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEAEQIRQNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKAKCLEDERLRTEDELSKYREIINRQKSEIQNLLDKVKITDQLHEQLQSGKQEIEHLKEEMESLNSLINDLQKDIEGSRKRESELLLFTEKLTSKNAQLQSESSALQSQVDNLSCTESQLQSQCQQMGQANRNLESKLLKEEELRKEEVQTLQAELSAAQTEVKALSTQVEELKDELVTQRRKHASNVKDLSKQLQQARRKLEQTENGNHDKDISSMGSRSSSSGSLNAR-ISAEDRSPENTSSS--VAVDNFPEVDKAMLIERIVRLQKAHARKNEKIEFMEDHIKQLVEEIRKKTKIIQSYVLREESGTLSSEASDFNKVHLSRRGGIMASLYTSHPADSGLTLELSLEINRKLQAVLEDTLLKNITLKENLQTLGTEIERLIKHQHELEQRTKKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z3E2-1", "uniprot_id": "CC186_HUMAN", "id": "Q7Z3E2-1", "name": "Coiled-coil domain-containing protein 186", "aln": "-------------------------MSETDHIASTSSDKNVGKTPELKEDSCNLFSGNESSKLENESKLLSLNTDKTLCQ-PNEHN---------NRIEAQENYIPDHGGGEDSCAKTDTGSENS--EQIANFPSGNFAKHIS-----KTNETEQKVTQILVELRSSTFPESAN---------EKTYSESPYDTDCTKKFISKIKSVSASEDLLEEIESELLS--TEFAE-HRVPNGMNKGEHALVLFEKCVQDKYLQQEHIIKKLIKENKKHQELFVDICSEKDNLREELKKRTETEKQHMNTIKQLESRIEELNKEVKASRDQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKKLRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHKETKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKVKCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGKQEIENLKEEVESLNSLINDLQKDIEGSRKRESELLLFTERLTSKNAQLQSESNSLQSQFDKVSCSESQLQSQCEQMKQTNINLESRLLKEEELRKEEVQTLQAELACRQTEVKALSTQVEELKDELVTQRRKHASSIKDLTKQLQQARRKLDQVESGSYDKEVSSMGSRSSSSGSLNAR-SSAEDRSPENTGSS--VAVDNFPQVDKAMLIERIVRLQKAHARKNEKIEFMEDHIKQLVEEIRKKTKIIQSYILREESGTLSSEASDFNKVHLSRRGGIMASLYTSHPADNGLTLELSLEINRKLQAVLEDTLLKNITLKENLQTLGTEIERLIKHQHELEQRTKKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6Y8-1", "uniprot_id": "A0ACD6B6Y8_DANRE", "id": "A0ACD6B6Y8-1", "name": "", "aln": "MEPLDSQSELSPASDPSPSPEVSTGLEESTDVLSNGSDPVLQEQEEETEPDSLELDASLSGSVDKETQRQDTDMEVQEDEGAGEHAPADVNISCDSGTASIEDSRTQDNAGESLPAVLDGQLECSGIEETTDALPQSFSSVLNGTDELKTANGQTELTRTHMTPTSSSHAEELPDVVSVLQNSQTNANLNPYDTECSRKLLSEIERSLSQESLLDELEDELLNSQSEGVRKGSHPNGLQKDQNSMVLFEKCVQYKYSQQEKAIKGLLEENKKHQELILGICSEKDNMRDELKKRMETEKQHLYTIKKFESRVEELTKELKDSRDKLVHQDQAAKNAIQQMQREMAYRLEQANKKCEEARQEKETMVMKYVRGEKEALDLRREKEQLEKKLREATAEVDKQARRGNTLAQEKGRLQQLYDAKENEVTRLMRELEKVKEEINSHVIKVKWAQNKLKSETDSHKETKDRLKETTAKLTQAKEETEQIRKNCQDMIRTYQESEEIKSNELDAKLRETKGELEKQKQEQTDQLEMHKAKIKELEDLKRTFKEGMDELTTLRTKVKCLEDERPRWEDELCKYREIINRQKAEIQNQREKLTAITRLEEQHQRDEQEIASLQEEVENLNSQITDLQRDIEGSRTREAELLGFTEKLSSKNAQLQSESNSLQAQLDRLNSSSRELHNKLEDTERCLSDMTDRLKTEEQQRQEEVLALQTERTSLQTETSQLKTRVEELRDELVTQKRKQAVNIKDLTKQLLQARKKLEQVENGGCDREGSSMGSRSSSSGSLNARGSSMDDRSPENQSGSSVVVVDSFPEVDKAVLVERIVRLQKAHARKNEKIEFMEDHIKQLVEEIRKKTKIIQSYVLREESGALSSEASDFNKAHLSRRGGIMASLYTSHPADSGLTLDLSLEINRKLQAVLEDTLLKNITLKENLQTLGSEIERLIKQQRLPDDTAGRK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*: .: * .** : * : .. .... *. ::. :: . : : : ..** . *. .: ..**. * * * * : : .*:. :. ** : : :*: **: .* .. . . ***:*::*::*::: :.:.** *:*.***. :* .. ***::*.::::.******: :* *** :* *::***:****::.******.:*:**:** ******: ***::* *:***.**:* *:*:*: ** :****:**:::*** *::**************:***********:****:*** **:***:*. *::*::.: : *:******:***::**.*.***:**::*:**::**:************:* ********:*****:********::***:******:****************** ******** **::******:******************** *****.******* * ****.**:*******:**** :*:. :*.** * .:*** *:**:*.*** *.***:******.**:*** ***:*:**********.:**:*.*.:..:. :*:.: :: : :: .:* .**: *:*** :**:* :. ***.. *.*:****:******:**:* .:***:*** ***:**:*.*.*. *:: **************** * :****** ..* *.**.**:****:*:*****************************************:******:**********.*******************.****:*******************************:*******:*: :: : : ", "identical_positions": 537, "similar_positions": 226, "identity": "56.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100318-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A198-1", "uniprot_id": "D4A198_RAT", "id": "D4A198-1", "name": "Neuralized-like protein 4", "aln": "MAAGSGGSGGSGAGPGPGPGPGGGGGPGSSGPGLGSSGGLGSGGELHPRTGRLVSLSACGRTARRQQPGQEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGVTALDPSVLDFPSSATGLKGGSWVVSGCSVLRDGRSVLEEYGQDLDQLVEGDRVGVERTATGELRLWVNGRDCGVAATGLPARVWAVVDLYGKCTQITVLPPEP----------------------GFSPSTPISTPPLEPLAPPEDSALSEQGTSVDEAFMVSPAQARPETFPNSLDSHNDFASMELSEVVSNAILSAYN-------------------------------------------GGLLNVSLSSPPAADGLASSGSATSP-ILTSNDALLFHEKCGTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRDNEMFEIRIDKLVDKWSGSIEIGVTTHNPNSLEYPATMTNLQSGTIMMSGCGILTNGKGTRREYCEFSLDELQEGDHIGLTRKSNSALHFFINGIDQGVATPLTPPVVYGVVDLYGMAVKVTIVHNNNHSDR---LRRN-------------------------NAILRALSPE---------GALRRAAPAASAEP---ERLLFHPNCGQKAAITHEGRTALRPHATDDFNHGVVLSSRALRDGEVFQVRIDKMVDKWAGSIEIGVTTHNPAYLQLPSTMTNLRSGTWMMTGNGVMHNGTTILDEYGHNLDRLKAGDTVGVVRREDGTLHFFVNGMTQGPAAWNVPPGVYAVVDLYGQAAQATIVDD-VEVPPVSEPLPEGNNQMSPSSPASAVGG---SDLRFHQLHGSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEAGVTAIRPEDLEFPNTMTDIDY-DTWMLSGTAIMQDGNTMRNNYGCDLDALGTGARIGMMRTAKGDLHYFINGQDQGAACSGLPPGKEVYAVVDLYGQCVQVSITNATGPMDNSLATSNT--ATEKSFPLHSPVAGVAHRFHSTCGKNVTLEEDGTRAVRVAG----YAHGLVFSTKELKAEEVFEVKVEELDEKWAGSLRLGLTTLAPEDMGPGAGSG-PGLPPSLPELRTKTTWMVSSCEVRRDGHLQRMNYGRNLERLGVGSRVGIRRCADDTMHILVDGEDMGPAATGIAKNVWAVLDLYGPVRSVAIVSSTRLEEPEGTQPPSPSSDTGSEGEEDEEGEEHGLRGQNQVGVMPTALEFLENHGKNILLSNGNRTATRVASYNQGIVVISQPLVPHMLVQVRIDFLNRQWTSSLVLGVITCPPERLNFPASACALKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTILGLRLDSSGGLHLHINGVDQGVAVPDVPQPCHALVDLYGQCEQVTIVSPDPGTASGKT---------------AGTQGDMEKADMVDGIKES----VCWGPPPAASPLKSCEYHALCSRFQELLLLPEDYFMPPPKR----------SLCYCESCRKLRGDEAHRRRGE------------------------------------------------PP---------------------------------------------------------------------------REYALPFGWCRFNLRVNPHLEAGTLTKKWHMAYHGSSVAVVRRVLDRGELG----------------------------------------------------------AGTTSILSCRPLKGEPGVGFE-----------------------------------------EPGENCAPPREEQPPAVLLSPSLQYAGAETLASKVQFRDPKSQRTHQAQVAFQVCVRPGSYT-------------------------PGPPSAALRELPDQHFSPS------ELEWVTKEKGATLLYALLVRVE--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5NCX5-1", "uniprot_id": "NEUL4_MOUSE", "id": "Q5NCX5-1", "name": "Neuralized-like protein 4", "aln": "MAAGSGGSGGSGAGPGPGPGPGGGGGPGSSGPGLGSGGGLGGGGELHPRTGRLVSLSACGRTARRQQPGQEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGVTALDPSVLDFPSSATGLKGGSWVVSGCSVLRDGRSVLEEYGQDLDQLVEGDRVGVERTATGELRLWVNGRDCGVAATGLPARVWAVVDLYGKCTQITVLPSEP----------------------GFSPPTPVPTPPLEPLAPPEDSALLEQGTSVDEAFMVSPAQARPETFPNSLDSHNDFASMELSEVVSNAILSAYN-------------------------------------------GGLLNVSLSSPPAGDGLASSGPATSP-ILTSNDALLFHEKCGTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRDNEMFEIRIDKLVDKWSGSIEIGVTTHNPNSLEYPATMTNLQSGTIMMSGCGILTNGKGTRREYCEFSLDELQEGDHIGLTRKSNSALHFFINGIDQGVATPLTPPVVYGVVDLYGMAVKVTIVHNNNHSDR---LRRN-------------------------NAILRALSPE---------GALRRAAPAAQAEP---ERLLFHPNCGQKAAITHEGRTALRPHATDDFNHGVVLSSRALRDGEVFQVRIDKMVDKWAGSIEIGVTTHNPAYLQLPSTMTNLRSGTWMMTGNGVMHNGTTILDEYGHNLDRLKAGDTVGVVRREDGTLHFFVNGMTQGPAAWNVPPGVYAVVDLYGQAAQATIVDD-VEVPPVSEPLPEGNNQMSPSSPSSAAGG---SDLRFHQLHGSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEAGVTAIRPEDLEFPNTMTDIDY-DTWMLSGTAIMQDGNTMRNNYGCDLDALGTGARIGMMRTAKGDLHYFINGQDQGAACSGLPPGKEVYAVVDLYGQCVQVSITNATGPMDNSLATSNT--ATEKSFPLHSPVAGVAHRFHSMCGKNVTLEEDGTRAVRVAG----YAHGLVFSTKELKAEEVFEVKVEELDEKWAGSLRLGLTTLAPEDMGPGAGSG-PGLPPSLPELRTKTTWMVSSCEVRRDGHLQRMNYGRNLERLGVGSRVGIRRCADDTMHILVDGEDMGPAAAGIAKNVWAVLDLYGPVRSVAIVSSTRLEEPEGTQPPSPSSDTGSEVEEDDEVEEQGLRGQNQVGIVPTALEFLENHGKNILLSNGNRTATRVASYNQGIVVISQPLVPHMLVQVRIDFLNRQWTSSLVLGVITCPPERLNFPASACALKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTILGLRLDSSGGLHLHINGVDQGVAVPDVPQPCHALVDLYGQCEQVTIVSPDPGTASGKI---------------AGTQGDMEKADMVDGIKES----VCWGPPPAASPLKSCEYHALCSRFQELLLLPEDYFMPPPKR----------SLCYCESCRKLRGDEAHRRRGE------------------------------------------------PP---------------------------------------------------------------------------REYALPFGWCRFNLRVNPHLEAGTLTKKWHMAYHGSSVAVVRRVLDRGELG----------------------------------------------------------AGTTSILSCRPLKGEPGVGFE-----------------------------------------EPGENCAPPREEQPPPVLLSPSLQYAGAEMLASKVQFRDPKSQRTHQAQVAFQVCVRPGSYT-------------------------PGPPSAALRELPDQHFSPS------ELEWVTKEKGATLLYALLVRVE--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JN8-1", "uniprot_id": "NEUL4_HUMAN", "id": "Q96JN8-1", "name": "Neuralized-like protein 4", "aln": "MAAGSGGSGGSGGGPGPGP--GGGGGPSGSGSGPGSNGGLGSGGELHPRTGRLVSLSACGRTARRQQPGQEFNHGLVLSREPLRDGRVFTVRIDRKVNSWSGSIEIGVTALDPSVLDFPSSATGLKGGSWVVSGCSVLRDGRSVLEEYGQDLDQLGEGDRVGVERTVAGELRLWVNGRDCGVAATGLPPRVWAVVDLYGKCTQITVLPPEP----------------------GFSPPTPIPTPPLEPLAPTEDSALAEQGTSADEAFMVSPAQARPETFPNSLESHNDFANMELSEVVSNTILSAYN-------------------------------------------GGLLNVNLSSPPAGEGLGSSGAATSP-ILTSNDALLFHEKCGTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRDNEMFEIRIDKLVDKWSGSIEIGVTTHNPNSLEYPATMTNLQSGTIMMSGCGILTNGKGTRREYCEFSLDELQEGDHIGLTRKSNSALHFFINGIDQGVATPLTPPVVYGVVDLYGMAVKVTIVHNNNHSDR---LRRN-------------------------NAILRALSPE---------GALRRAAPAAQAEP---ERLLFHPNCGQKAAITHEGRTALRPHATDDFNHGVVLSSRALRDGEVFQVRIDKMVDKWAGSIEIGVTTHNPAYLQLPSTMTNLRSGTWMMTGNGVMHNGTTILDEYGHNLDRLKAGDTVGVVRREDGTLHFFVNGMTQGPAAWNVPPGVYAVVDLYGQAAQATIVDD-VEVAPVPEPLPEGNNQVSPSSPSSGAGG---SDLRFHQLHGSNAVITNGGRTALRHNCRSEFNDAIVISNRALRDGELFEIVIQKMVDRWSGSIEAGVTAIRPEDLEFPNTMTDIDY-DTWMLSGTAIMQDGNTMRNNYGCDLDALGTGARIGMMRTAKGDLHYFINGQDQGAACSGLPPGKEVYAVVDLYGQCVQVSITNATGPMDNSLATSNT--ATEKSFPLHSPVAGVAHRFHSTCGKNVTLEEDGTRAVRAAG----YAHGLVFSTKELRAEEVFEVKVEELDEKWAGSLRLGLTTLAPGEMGPGAGGGGPGLPPSLPELRTKTTWMVSSCEVRRDGQLQRMNYGRNLERLGVGSRVGVRRGADDTMHILVDGEDMGPAATGIAKNVWAVLDLYGPVRGVSIVSSTRLEESEGTQPPSPSSDTGSEGEEDDEGEEHGLGGQNEVGIIPTTLEFLENHGKNILLSNGNRTATRVASYNQGIVVINQPLVPQLLVQVRIDFLNRQWTSSLVLGVITCAPERLNFPASACALKRAAWLLRGRGVFHNGLKICEKFGPNLDTCPEGTILGLRLDSSGGLHLHVNGVDQGVAVPDVPQPCHALVDLYGQCEQVTIVNPEPGAASGKS---------------AGTQGDMEKADMVDGIKES----VCWGPPPAASPLKSCEYHALCSRFQELLLLPEDYFMPPPKR----------SLCYCESCRKLRGDEAHRRRGE------------------------------------------------PP---------------------------------------------------------------------------REYALPFGWCRFNLRVNPRLEAGTLTKKWHMAYHGSNVAAVRRVLDRGELG----------------------------------------------------------AGTASILSCRPLKGEPGVGFE-----------------------------------------EPGENCAPPREEQPPPVLLSPSLQYAGAETLASKVQFRDPKSQRTHQAQVAFQVCVRPGSYT-------------------------PGPPSAALGEPPDPHFSPA------ELEWVTKEKGATLLCALLVRVE--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QMX5-1", "uniprot_id": "A0A8M9QMX5_DANRE", "id": "A0A8M9QMX5-1", "name": "Neuralized-like protein 4", "aln": "-----------------------------------------MAAELHPRSGKLIGLSNSNRTAQRNQPVQEFNHGLVLSREPLRDRDVFTVRIDKKVNSWSGSIEIGVTALDPAGLEFPSSATGLKGGSWIVSGCSVLKDGRSVLEEYGRDLDQLGEGDRVGIQRNGKGELHLWVNGQDCGAAASGLPSRLWAVVDLYGKCTQVTVVSCEPPSEMEGDEDEEVEDEIVSTQAVSIMADACRSHDDRAAVLTAAAATTERMNGSAEEVPEVSRTHSRPDKFPNNFEPDSVLTEHQLFDVFNNAIVSLYRSEDDGAEDLNVGGGGGGSDSSRGGTGSNGGGRGTGSDSGIGGGGGGGGSSSNSSPAGNAGGAAGLGVGTGGMTTNDALLFHEKCGTLIKLSNNNKTAERRRPLDEFNNGVVMTNRPLRHNEMFEIRIDKLVDKWSGSIEIGVTTHNPNNLDYPATMTNLRSGTIMMSGCGILTNGKGTRREYCEFSLDELQEGDHIGLMRKASGALHFYINGIDQGVAANQTPGVVYGVVDLYGMAVKVTIVHNHNHSDR---LRRN-------------------------NAIMRALSPD---------VGRPRPALSLTPEPDIPDRLLFHPNCGQKAAIISDGRTALRPHATDDFNHGVVLSNRPLHSNEVFQVRIDKMVDKWAGSIEIGVTTHNPAYLQLPSTMTNLRSGTWMMTGNGVMHNGTTILDEYGHNLDRLKAGDTVGVVRKEDGSLHFFVNGVPQGPAAWNVPPNVYAVVDLYGQAAQATIMDDMADLPPLPDDSSEGPTAMSPGSPCSISGATAANDLRFHQLHGTNAVITNGGRTALRQNCRSEFNDAIVISNRCLREGELFEIVIQKMVDRWSGSIEAGVTAIRPEELEFPNTMTDIDY-DTWMLSGTAIMQDGNTMRNNYGCDLDSLTTASRIGMMRTATGDLHYFINGLDQGVACTGLPS--EVYAVVDLYGQCVQVSITSSSGPLDNSLCTSN---ITEKSFPIHSPVAGVAHRLHSKHGKNVVLLGDGCQALRVGG----YAHGIVFSAKELKTDEVFEVKINKVDERWSGSLHVGLTTLQPPDLPSCPLSG---LSPSLTQLRTKVTWVLAGSEVRRNGVLQRQNYGCSLDRLTVGNRVGVKRCSDDTMHILIDGEDMGPAATAVAKNVYAVLDLYGKVTAVSIVSSTLVEDSESVKAPSLSSDSCSEGEEDCTPVR---ECENEPPLVPTVMTFLENHGKNIQLSNQNLTAARVSSYNQGLLVTAQALPRQQLFQFQIDRLNPSWTSSLSLGVIGHSPDRLNFPSTACCLKRSVWLLQRDSVFHNSLKICENYGPNLDTCPEGTVLGLLVDSSGCLHLFVNGMDQGVAAQDIPSPCYALIDLYGQCEQVTIVANHVPVVGGERG-------------DMRCQGDMEKADMVDGIKES----VCWTPPPEVNPNKTCEYQALCSRFKDLLTLPDGYFNEDAKY----------NLCYCESCHKLRGDEAYYKRGE------------------------------------------------PP---------------------------------------------------------------------------RDYALPFGWCRFALQIKTHCEVSNAFKKWHIAYHGTSVGSLRRTLDHNQLLS---------------------------------------------------------AESSSIFSSSSVKTEGHGSYG-----------------------------------------EPEENSAPERD--IPRVQLSPTMRYSGLEVFAPKVQFRDPRSLRCHQAQVGFQVCVRPGSYK-------------------------VGPSSLGISEPLDPRFSNA------EIEWITKEKGGTLLYGLLIRVE--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A1L4AAD6-1", "uniprot_id": "A0A1L4AAD6_DROME", "id": "A0A1L4AAD6-1", "name": "", "aln": "-------------------------------------MTGREAQSFHTRCGRSIRLYNNNRMAQR--SMRDFSHALVFSAEPLEDDVLFEVVIEKKNTYWGGSIEIGVTAESPDDLELVACATAMRNGTWVMSGIDVRKDGRRLFEFYGTDLETLNENDRVGVMRTSGNDLVFYVNGESQGVAAKNMPKPLWALVDLYGRCVQVSLCPRDG---------------------------------------------------SGSGELLDSPLQQPLQQVVQNLD-----VAMNVNIVVDSDAWMQGN-----------------------------------------------------------GSVSG---------ADDRLCFHTRCGSLVKLSPNFRSAERRRPLDEFNNGVVMTHRPLRDNELFEIRIDKLVDKWSGSIEVGVTTHNPAVLHFPATMTNMRSGTIMMSGCGILTNGKGTRRQYGEFNLDELREGDRVGMMRKANGNLHNYINGQDQGVAATRAPSTLWGVIDLYGMTIKVTIVDRDEREQQNLVTRRNNIVAGMTACSSGAGAQHTQHQQHSGTPTLSLLSPESEMNAAGAAGGLSETISSTRAIARNDDRLTFHHICGTHATVTQSGRTALRPNAADDFNNGVVLTRRPLRPNELFQVRLERVVTKWAGSVEMGVTTHSADELDFPFTMTNVRSGTWMMTGNGVMQNGVTVIEQYGQNLDRLQVGDRVGVVRKDDGTLHFWVNGVDQGPAANNVPERVYGVIDLYGQAAQASIVDTSECGSPDTGNSTISNTTLYSEVP-----------LRFHSIHGANAGISNSGLTASRPNSLAEFNDAIVFSNRPLRQRELFEVELETMVRHWSGNIEIGVTGTRPEDIQLAPNATDLEASDTIILCGPMIFHNRKTIRTNILLDLDTLGPSTRVGVMRNGD-FIHFFVDGMDQGPACECHAP--NIWAIIDLYGQCAQVSLTQTQLDIRAPYATSENSQSCQATSVIQHPAMETKHRWTCVSG-NVSLTKDWTEASRFTGAAAPLSHCLVFSEHPLSVGSPFEIKLTSVNSMFAGCLSIGVTDLNLSDE-----SVRKKLPTSIRRIPAN-VWYVSGNEVCFNSSCLQRSLAS-LEWLRVDDRITLER-VENSLNILLNSENVNIHFHNVPNDVYVVAELRGSTMGIQVISAQGPASPLRPCSLRLQDSMDFGVDPLNKQDSSMLESIDSEALN---YEFLDVSQKNARLSDDRRSVTRIKSYNQSIVCLNKPLCKGESISIKVDALNNKWKGTVGLGVLSASP--QTVPISLLDFKRSCWLATHDYVNINGQVMPSKYGDALEQIQVGTVITLTLTHAGMLIIMIGSTNLEDLASGLPNHVYPVFDVYGKCEKITLITGNDAGRTGNANGTPILEAPEALELDNGMPQQCEKAHLEMHEKEKDTEQVCESGPSTSGAPSNAMTRSVMESVSENLLLNISIKNRTLEQQRNELGGSSSTCCLRESLQLQHNTNLNIQRSQSTQRFQNSLNTSATAAGSSGTSGCTANTQHLSNSGVYDTNKEYDDLPNPPNPLVNSVDEASGAITSVSTTIDHSENNAEALELSASNEREMSGEPALNDNVLEDDEIDYMNHLLLLQQLQQNEYTRHHLMPDQASLLNLDLPSLNSMESDTNSVGQTRPSGGTDSLRSTATGASVEQNDCEYLRQVRRFCASLVLPQAFFDSRLEPVCFCLKCSGPSIGGNGDKLEGWVYFKLNQQTVNVLSTSTSTASAGGGASSATAPQVHFDLNGDWLPFYYMTRVDKIRAILDRGQPLPLETDPDEEPAAAALKDEPGTRLELYYSPNATVIEPVLPQHHFASEQGLHRISTSFEVYVRRQSISGVTTGKAAAEAKRRSLGSTDHDHGGTGQGADGVGVTPSATLNESSVHLLNDLCWFTKEAGACIINALIIKLDRIEESESH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:*.* *: : * .* *:* . ::*.*.**:* ***.* :* * *::* . *.********* .* *:: :.**.::.*:*::** .* :*** ::* ** **: * *.****: *. .:* ::***.. *.**..:* :**:*****:*.*::: . : * . * : : . :.:: . :: *... . . :* ::* * ** :**:*:*** * ::*****************:****.**:*****************:******* *.:******::********************:* **.****:***::*: **:.. ** :*** *****: :* .::**:*****::*****...::.:: *** .. : ***: . .. : . . :** ** ** :*:: .*******:*:****:****: *.*: .*:****::::* *****:*:*****.. *::* ****:*************:**.*::::**:*****:.** *****::**:***:***: ***** *** **.*:*********:*:* .* . . . . : . * ****.:**:** *:*.* ** * *. :*******:*** **: ****: ::.** :***.** ***. ***::::. . **:: ** :*.*. *::: :*:*.* ***:* ..:*:*:**.. :*:*::* *** ** .. :::*::******.***:*.: : . .**: : : :: *. . ** . * ** * * .* * * :* :*** : * . . **:*: .::. ::*.* :*:* * : . *..*: .: :: .* ::. ** :. : . . *: * *..*: :.* :::::**::.*::. :.::*:.* :* * . .: ::*: .. . ... : :. : **: ** **: . :.:*: ****.:: :.* ...::* ** .*..:: ***: .* ..* : :**: ** * *. : .::* *: **:: * : :* * : :.. : . .:*. :.:.*:**:**::*:: . *: : ***.: **. ** *. .. ... ::: . ..: * * . : . * ** : :. : :*.: ** *.: :* . : * : . . . :. : . .. :* . .: : .::* . . . . :* *: *. * . *. . . *.: . . *: ...*:* ** * . * : .: . :. : :: *.*** *. :: .*::::: ", "identical_positions": 519, "similar_positions": 468, "identity": "26.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100318-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9P1Z0-1", "uniprot_id": "ZBTB4_HUMAN", "id": "Q9P1Z0-1", "name": "Zinc finger and BTB domain-containing protein 4", "aln": "MPPPAEVTDPSHAPAVLRQLNEQRLRGLFCDVTLIAGDTKFPAHRSVLAASSP-----FFREALLTSAPLPLPPATGGAAPNPATTTAASSSSSSSSSSSSSSSSASSSSSSSSSSPPPASPPASSPPRVLELPGVPAAAFSDVLN---------------FIYSARLALPGGGGDGAAVAEIGALGRRLGISR---LQGLGEGGDAWVPPTPAPMATSQPEE----------DSFGPGPRP-----AGEWEGDRAEAQAPDLQCSLPRRPLPCPQCGKSFIHPKRLQTHEAQCRRGASTRGSTGLG-AGGAGPGGPAGVDASALPPPVGFRGGP---------------------------EHVVKVVGGHVLYVCAACERSYVTLSSLKRHSNVHSWRRKYPCRYCEKVFALAEYRTKHEVWHTGERRYQCIFCWETFVTYYNLKTHQRAFHGISPGLLASEKTPNGGYKPKLNTLKLYRLLPMRAAKRPYKTYSQGAPEAPLSPTLNTPAPVAMPASPPP------------------------------GPPPAPEPGPPPSVITFAHPAPSVIVHGGSSSGGGGSGTASTGGSQAASVITYTAP------------PRPPKKREYPPPPPEPAATPTSPA-TAVSPATAAGPAMATTTEEAKGRNPRAGRTLTYTAKPVGG---IGGGGGPPTGAGRGPSQLQAPPPLCQITVRIGEEAIVKRRISETDLRPGELSGEEMEESEEDEEEEDEEEEEEDEEESKAGG---------------------------------------EDQLWRPYYSYKPKRKAGAAGGASVGGSGLPRGR--RPPRWRQKLERRSWEETPAAESPAGRARTERR--------------------------------------------------------------------------HRCGDCAQTFTTLRKLRKHQEAHG--------------------------------------------------------------GGSHSSRAGRRPSTRFTCPHCAKVCKTAAALSRHGQRHAAE---------------------------------RPGGTPTPVIAYSKGSAGTRPGDVKEEAPQEMQVSSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SGEAGGGSTAAEEASETASLQDPIISGGEEPPVVASGGSYVYP------PVQEFPLALIGGGREPGGGRGKSGSEGPVGAG------EGDRMEGIGAAKVTFYPEPYPLVYGPQLLAAYPYNFSNLAALPVALNMVLPDEKGAGALPFLPGVFGYAVNPQAAPPAPPTPPPPTLPPPIPPKGEGERAGVERTQKGDVG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5F293-1", "uniprot_id": "ZBTB4_MOUSE", "id": "Q5F293-1", "name": "Zinc finger and BTB domain-containing protein 4", "aln": "MPPPAEVTDPSHAPAVLHQLNEQRLRGLFCDVTLIAGDTKFPAHRSVLAASSP-----FFREALLASAPLPLPPVTGGSAPSPATTTAASSSSSS---------------------PPPASPHSSSPPRVLELPGVPAAAFSDVLN---------------FIYSARLALPGGGGDGAAVAEIGALGRRLGISR---LQGLGEGGDTWVPPAPTSMVTSDPTE----------DGLGAGPRT-----DGEWVGDKAEALTPDSQ---PRRPFPCPRCGKSFIHPKRLQTHEAQCRRGSNTRGSAGLG-PGVSGSGGPAGVDASALPQPVGFRDGP---------------------------EHVVKVVGGHVLYVCAACERSYVTLSSLKRHSNVHSWRRKYPCRYCEKVFALAEYRTKHEVWHTGERRYQCIFCWDTFVTYYNLKTHQRAFHGISPGLLASEKTPNGGYKPRLNTLKLYRLLPMRAAKRPYKTYSQGAPEAPLSPSLHTPAPAAMPASPQP------------------------------LPPPAPEPGPPPSVITFAHPAPSVIVHGSSSSGAAGGGPAGTGGSQAASVITYTTP------------PRPPKKREYPPPPPEPTATPTSPASTAVSPATAAGP--ATATEEAKGRNLRAGRTLTYTAKPVGG---LSGSGGSPTGTGRGSSQLQAPPPLCQITVRIGEEAIVKRRISETDLRPGELSGEEVEESEE-EEEEEEEEDQEEQEESKAGG---------------------------------------EDQLWRPYYSYKPKRKAGATAGGASGVSGLPRGR--RPPRWRQKLERRGWEETPSVEGPGGRGRGERR--------------------------------------------------------------------------HRCGDCAQAFATVRKLRKHQEAHS--------------------------------------------------------------GGSHTSRTGRRSSTRFTCPHCAKVCKTAAALNRHGQRHAVE---------------------------------RPGGTPTPVIAYSKGSIGTRPTDVKEEAPQEMQVSSS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SGEAGSGSAAAAEASESASLQDPVISGGEEPPVAG-GGSYVYP------PVQEFPLALIGGSREPSAGKGKPGNEGSLGAS------EGDRMEGMGTAKVTFYPEPYPLVYGPQLLAAYPYNFSNLAALPVALNMVLPDEKGGGALPFLPGVFGYAVNPQAAPPTPPPP----LPLPVSPKGIGGMTGVERTQKGDVG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B7G9-1", "uniprot_id": "A0ACD6B7G9_DANRE", "id": "A0ACD6B7G9-1", "name": "", "aln": "MKHRNKHIRGDRMGEGTEEANSAKTTRISLSFPLSAGLPGFSAQKHCSSSPPTSSSDVHSKDGLDGTAWMEETYRDKQLSKTSSKTDRLPCSSSSFPVDLTAPVSKNCKSSLSVSVDGSGSRYPASPLQHSNKMDSPKETAGVSLNNGYKEHSTTETAHILFNLSARAYQDQGVKDPENSKGKKRKANSLHVELSLPLPSINPHSSSSTPPPHSPSSVSLTSSPLTHPTASFHDSFRAVPKPELLCGVCHRLFSTASSLTVHMRLHRGGRVLSCRHCGKAFIHNKRLQSHEATCRQGLPAFPVPPKEEPLEEGEVEGERTDEAAEPEQLGQETRPGQPAKKVRDLTARHAEALTCGDTLGDDDHFVKVVDGHIIYFCSVCERSYMTLSSLKRHSNVHSWRRKYPCHFCDKVFALAEYRTKHEVWHTGERRYQCIFCWEAFPTYYNLKTHQKAFHGINPGLISSEKTANGGYKQKVNALKLYRLLPMRSLKRPYKTYSQPMADGLLTSDSTDNLHLSVDGSLPQPLDTKKLESFLKDLQNQDIKAETEGFPIRLDIEQGTEIASPQTDMTLEAGQVEDSDLWPSGNNNDKGQTPKCPERAVSSVIAFARSKPSVIMHSTAVSSSVIVHRNKTDSEERKRSPEKHQLAKTIKKHSQKEPTEAYREWNAVGLDPEVSKIRHPTEKLHKGRKVHHKTESSKTIPLAVGSEVKGSGPLCQITVRIGEEAIVKRSISETDLRRDKSPTRSKPKKSNLLQDKQREQRHTHHHQRKHRNSNQEGKEREPKRKSSKVKTKVRKYFFRQEVREDRNDHDVEDNLWRPYYSYKPKRKALHIQGAKAWKRKMHYKRSLRPMRRAERLMKNHLNKDAEDEDADEREEKRQKEKTEQKEVSDPVKTEVKEMPHSFPVSLRTEQKEKEKGTNGKPNLPLPSTVPQATPNPTHTASSIIKQRWSEDQASECGTCGRWFSSPRKRDKHEMTHLFEFVCMHCRAPFPSQFKLEEHQRSQHPKNKPLSAPTFYTSQSSKGEVEMKVADDDGVNGRSIEKGSPVRLGRRPLIRYTCSKCDKVCKTSAALNCHLKRHELGSLTEVEDAHEKQDMPSYTPSAVDTIPSIGLDTNCEQVQPVSVIYYSKPECQNTNNELGEKMEEHQRVRDCESPKVTKNEKVHSPRCAQFSQVIHSPTLERFNVISPNLPSVLVMNGAECLDYRTPEKQNLEKLDQQKRSQTPSNRQIQVSQMLTEPQIRRETTPSVPISLKTGRGYAFTDCDKNPNQDFSDLQDAQDLRIFPQSSSQAQDLSRPTILAKKKELDEQIKHPSNILKAQSCNEEVSLLVPKEEPLSPIPSPTCSVIQTTPKGLSQRYSKSTCHSPEPLDLQLRPQLDHNQSHRGRHNSEKQGLMLPANSAGIIDPSSPALLNPQVPAAEPELKDITSGTHTEHHRVSGYPVQEYSLPMVIPGGYCSGKNQEEQILMSYPAGPLPFPPLGKMVPHADSTKLPFYPDPYHLLYGPQLLP-YPY---NLAALPMALNMMASGDKE--PLPFLP-FFNYAAAAAPLTGTLPHP----LVMNPSLYNSGGSSSTKQDNP----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : .: .: *. : : ...* ** . *.*:: ::... . ::.* :* : . : ..:.* ..**** ..* .:** : : . * : . ** * *** * * .. * :. * .:. ..: .**. :. .* . . *.: . *:. . . *.: : . : * :.* :***:*** ****:*** **:* : . . * .* :* * :* . * :*.****.**::*.*:.*****:********************::*:****************************::* *********:*****.***::****.***** ::*:**********: ********* .:. *:. :: .* ..* ..* : :*: . *... . .. .:***::: . . :*: . . . :. . .::. : * * :* * : ...: * * * .. * . *:::.. ***************** ******* .: . .. :..: ::::.*: . ...: * . **:************** *. : * ** * ::* :. :: . *.. * . .:: .** *.: *:: ** **: :* . . * ***. *:**.:* *****:***. * :** *..** *** . . :: *: :. :* .. .* ..:*. ..:.:* :* :...* .*::. ****:.*.:: . .. . : . *. *. : .::*:.***:** *:******. *** ******:****: ..:* .***** .*.**. . . . : * * * . . * :..:: : ", "identical_positions": 325, "similar_positions": 291, "identity": "20.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100318-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P07148-1", "uniprot_id": "FABPL_HUMAN", "id": "P07148-1", "name": "Fatty acid-binding protein, liver", "aln": "MSFSGKYQLQSQENFEAFMKAIGLPEELIQKGKDIKGVSEIVQNGKHFKFTITAGSKVIQNEFTVGEECELETMTGEKVKTVVQLEGDNKLVTTFKNIKSVTELNGD--IITNTMTLGDIVFKRISKRI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IRM6-1", "uniprot_id": "A0A0R4IRM6_DANRE", "id": "A0A0R4IRM6-1", "name": "", "aln": "MPFSGKFELEKYEGWEEFMTAIG-HQELLKKANDGKTQFEIQENGNDYCLTTRSGGKVLNNSFTIGQDTEIQMLSGDKVKTVVHKDG-QKLKAALGNITLTWELLDENTLLITLSTADNVAYKRFSKRVA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.****::*:. *.:* **.*** :**::*.:* * ** :**:.: :* :*.**::*.**:*:: *:: ::*:******: :* :** ::: **. . ** .: :: . * .::.:**:***: ", "identical_positions": 51, "similar_positions": 51, "identity": "39.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100319-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9G5-1", "uniprot_id": "D4A9G5_RAT", "id": "D4A9G5-1", "name": "", "aln": "MMMYIRQRKETKPVEVSEDFPSP-------KEDVKLEKKLPSGCASG-----------RFWKILSSAVGGTVALCIGLLTSVYLATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLQAPTLLQGFHGLIYDNKTESMRTINLLQRMNIYQEVFLSVLYRVLP--IQKYLEPVYFYIYTLFGLQAVYVTALYITSWLLSGTWLSGLLAALWYVTNRIDTTRVEFTIPLRENWALPFFAIQIAAITYFLRPNLQPLSERLTLLAIFVS---TFLFSLTWQFNQFMMLLQALVLFILDSLDMLPAVKATWLYGIQISCLLLVCMLQFFNSMILGSLLISFNLSVLIVRKLQKNLKTG--------TFLIRIWKLLLHLLLVFCLTLFLNNIIKKILNLKS-----------DEHIFKFLKAKFGFGATRDFDANLYLCEEAFGLLPLNTFQRLSETLLFYAYMFVLLVTVVTASVVAFHNLSDSTSLQPVDQTRKRVVDLKPEAAYNLIHTILFGVLALSTMRMKYLWTSHMCVFASFG----LCSSEIWELILRLVHLCNPKRIWVMRYSVPVLTLLCLCCKSWPGMMDELSELKEFYDPDTVELMNWINSNTPR------KAVFAGSMQLLAGVKLCTGRTLTNHPHYED--KSLRERTQAVYQIYAKR---SPE---------EVHALLRSFGTDFVIL----------------------EDSICYERRHHRG-----------CRLRDLLDVANGHEMDGPGESDPDLRP---------------------------ADHPRFCEEIKRNLPSYAAHFT------RVFQNKTFHVYKLSRNK------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q71B07-1", "uniprot_id": "D19L3_MOUSE", "id": "Q71B07-1", "name": "Protein C-mannosyl-transferase DPY19L3", "aln": "-MMYIRQRKETKPIEVSEDFPSP-------KEDVKLEKKLPSGCASG-----------RFWKILSSAVGGTVALCIGLLTSVYLATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLQAPTLLQGFHGLIYDNKTESMRTINLLQRMNIYQEVFLSVLYRVLP--IQKYLEPVYFYIYTLFGLQAVYVTALYITSWLLSGTWLSGLLAALWYVTNRIDTTRVEFTIPLRENWALPFFAIQIAAITYFLRPNLQPLSERLTLLAIFVS---TFLFSLTWQFNQFMMLLQALVLFILDSLDMLPAMKATWLYGIQISCLLLVCTLQFFNSMILGSLLISFNLSVLIVRKLQKNLKTG--------SFLTRIWKLLLHLLLVFCLTLFLNNIIKKVLNLKS-----------DEHIFKFLKAKFGFGATRDFDANLYLCEEAFGLLPLNTFQRLSETLLFYAYMFVLVVTVVTASVVAFHNLSDSTSLKSMDQTRKRAVDLKPEAAYNLIHTILFGVLALSTMRMKYLWTSHMCVFASFG----LCSSEVWELLLRLVHLCNPKRIWVLRYLVPVLTLLYLCYKSWPGVMDELSELKEFYDPDTVELMTWINSNTPR------KAVFAGSMQLLAGVKLCTGRTLTNHPHYED--KSLRERTQAVYQIYAKR---SPE---------EVHALLRSFGTDFVIL----------------------EDSICYERRHHRG-----------CRLRDLLDVANGHEMDGPGESDPDLRP---------------------------ADHPRFCEEIKRNLPSYAAHFT------RVFQNKTFHVYKLSRNK------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZPD9-1", "uniprot_id": "D19L3_HUMAN", "id": "Q6ZPD9-1", "name": "Protein C-mannosyl-transferase DPY19L3", "aln": "-MMSIRQRREIRATEVSEDFPAQ-------EENVKLENKLPSGCTSR-----------RLWKILSLTIGGTIALCIGLLTSVYLATLHENDLWFSNIKEVEREISFRTECGLYYSYYKQMLQAPTLVQGFHGLIYDNKTESMKTINLLQRMNIYQEVFLSILYRVLP--IQKYLEPVYFYIYTLFGLQAIYVTALYITSWLLSGTWLSGLLAAFWYVTNRIDTTRVEFTIPLRENWALPFFAIQIAAITYFLRPNLQPLSERLTLLAIFIS---TFLFSLTWQFNQFMMLMQALVLFTLDSLDMLPAVKATWLYGIQITSLLLVCILQFFNSMILGSLLISFNLSVFIARKLQKNLKTG--------SFLNRLGKLLLHLFMVLCLTLFLNNIIKKILNLKS-----------DEHIFKFLKAKFGLGATRDFDANLYLCEEAFGLLPFNTFGRLSDTLLFYAYIFVLSITVIVAFVVAFHNLSDSTNQQSVGKMEKGTVDLKPETAYNLIHTILFGFLALSTMRMKYLWTSHMCVFASFG----LCSPEIWELLLKSVHLYNPKRICIMRYSVPILILLYLCYKFWPGMMDELSELREFYDPDTVELMNWINSNTPR------KAVFAGSMQLLAGVKLCTGRTLTNHPHYED--SSLRERTRAVYQIYAKR---APE---------EVHALLRSFGTDYVIL----------------------EDSICYERRHRRG-----------CRLRDLLDIANGHMMDGPGENDPDLKP---------------------------ADHPRFCEEIKRNLPPYVAYFT------RVFQNKTFHVYKLSRNK------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G0T2-1", "uniprot_id": "A0AC58G0T2_DANRE", "id": "A0AC58G0T2-1", "name": "", "aln": "-MRACRSRKSNSDDNSGSALHRPPLVNFGTKDNSRVYKSGQRGIEECLKLSWIHILGPNCWPAVVIAAGLLLAGVIGLFHAWCVYSIHENLLWFSHLKEVEREISFRTECGLYYSYYKQMLKAPTIQQGLYELTHDNTTESKRTINILQRMNIYQEVFLSILYRILP--IQTYLEPIYFYIYTVFALQTVYVIALFITSWLLSDSWLAGALSGVWYILNRVDTTRVEFTISLRENWSIPFFALQVAAITCYLRPKLKPIHQRVVLWLVFVS---TFCFCLTWQFNQFVLLVQALIIYTLDCLDFLTAEQVVSLYLMQVSSLLLVWLLQFCNSMILGSLVLSFIVSALFIKHFQTGLKMG--------GFVIRVGKLALHTLLVLALTFTINYSAKKVLQLKS-----------DEHIFKFIKAKFGFGATRDFDASLYLCEEAFGLLPLDTFERLAGTVLLYPYLCTLSVLFILLLLVALSNLSLNGLGQASGEKEDRTFKMRPDVAYNLMHTVFFGLLAFSTMRMKYLWTGHMCTIAAFG----VCGKEVWALYLRVLHCNTKTAMRLIRYSVPIVILAFLYYKFWPRLMEEISELREFYDPDTVELMEWISMETSPPTTGLLKCLCVATRIHRRALSYSTIGMKIEISKTKT--ETISALTDGVICYLNKKEGSTPEFEEGVSYILQKHTLSNKFGQMYLFVGPGSLKFKTTPHNFSEAAQTSAKEALCPPSPEMTGGEPDIFSRGGHISLRGQITEFHGVRMTRARVPIVDLKIKCLEGTFSVSLWREAALTELFVGDEVLITHLRPCVQETGTGKFHSSNYTTVEIAEGQMQETVVEVIGVSNVNHTCHFLGSDSQVYVVPQIVFAGNPDDLIARLPLHLSLKHVNRRVFQISEVSE--------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWR8-1", "uniprot_id": "DPY19_DROME", "id": "Q9VWR8-1", "name": "C-mannosyltransferase dpy-19 homolog", "aln": "-------------------MREP--------------------------------------NLYVILSHALIGCGFFFLYVQHVRVIFETRTNIQQLNQLEREALLRREDALYYAFYKQLAEGPDFWHGYEQLKNVTDIEYPHSVNVLQRFYVLPELVTAYFFHVVRSGFNPMVQPMQFYLEFVWLMGGVTLLVLYLYGTLLSENIFGGIYGVISYLMFHSFVAKIYERPLARENFAFPFIFLQMFYLCICIGRIIHRQRHTSRMFMIFAMSLFTACALLSWQFSTFIFTTQILIMMTSWNASALPTALVNAFVLDYSLSHLLGHALAFVMSHGNSQLLLTWQLSISLFLFLITMVRQLRHVRSRRLGHAQDLLNGDLFSLKFLMLTLLLASSVQTTLIELFNRAGVVSVTEGDQQHFFDICAHWALQVNVGFVAHLSACNPQYARVAWSELWQLVKTMIVKPYCMYGVVMLAMFFRRWRKSGAPVSALTEEQRERARKYVLEDFIEEHFVSMSDMSSKETEKQLYKCFRLLKSCDYDYERYKRAQASLRKEQPPARDDFMQDIKRLRAQINRNSVKQRKERAQETKEAATDGASTPTEEEDKDPEAESESKKKNQEPGSGETETESAADPTETPPSRSADNEEEEEEHSATAAGCGSNSSGHRQRKRSSSRRSSVVPTANAQILNMHYVYSFLQMLVFTLIGLAVRKLFFLSFTQG------CVIAPTVCSKLWYHRQR-----NIFWSVSLAVFLLSMFDPGMVNIREEYFPTRYSKSGDDLDSMLEWIKLNTERDAVFAGPVDIIGTVHLTTKRPIVNHAHLEM-----RQIAERTEHVYSVYSRQQSSDIYNQCAQLKIQYLIISLDECTNEVRDDCDLLAIWDDKQPAYQKYPQFCHELLHKNVPSFLKVFANDHYGIIKMFSQSVQINLKHNKMPEMSI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. : :: : :.*. :.:::::*** :* * .***::***: :.* : :* * . * :::*:***: : *:. : ::::: :: ::*: **: :: : : : .*:: . *** . :.* . . *: : .::: ***:::**: :*: : : :: . : :* * *:***. *:: * *:: . *.: . : . ** * * * ..*:::: :* : : . :: . : : *. : .: **: : :. * *:: * : *::.: .. .* * * *: :. :. . : :* *::. .* : . . : . . :. ::: :. .. * : : * .. . : . . : .: : : * * * *. . : . . . . . . : . : :: * ::: . : : : ::* * : . * : . : : : . .* : : ", "identical_positions": 78, "similar_positions": 199, "identity": "8.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100319-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZKB9-1", "uniprot_id": "TSH3_RAT", "id": "D3ZKB9-1", "name": "Teashirt homolog 3", "aln": "-----------MAAYVSDELKAAALVEDDIEPEEQVADGEPSAKYMCPEKE-LSKACPSYQNSPAAEFSSHEMDSESHISETSDRMADFESSSIKNEEE--TKEVQVPLEDTT------------------VSDSLEQMKAVYNNFLSNSYWSNLNLNLHQPSSEN--NGGGSSSSSSSSSSSCGSGSFDWHQSAMAKTLQQVSQN--RMLP---EPSLFSTVQLYRQSSKLYGSIFTGASKFRCKDCSAAYDTLVELTVHMNETGHYRD-DNHETDNNNPKRWSKPRKRSLLEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVTPVAAKIIPAARKKPSLELELPSSPDSTGGTPKAT---LSDASDALQKNSNPYITPNNRYGHQNGASYAWHFEAR----KSQILKCMECGSSHDTLQELTAHMMVTGHF-IKVTNSAMKKGKPIMETPVTPTITTLLD--EKVQSVPLAATTFTSP--SNTPASVSPKLTVEIKKEVDKEKAVLDEKPKEKEK---ASEEEEKYDISSKYHYLTENDLEESPKGGLDILKSLENTVTSAINKAQNGTPSWGGYPSIHAAYQLPNMMKLSLGSSGKSTPLKPMFGNSEIVSPTKTQTLVSPPSSQTSPMPKTNFHAMEELVKKVTEKVAKVEEKMKEPDSKLSPPKRATPSPCSSEQSEPIKMEASSG---SGFKSQENSPSPPRDVCKEASPSAEPVENGKELVKPLSGGSLSGSTAIITDHPPEQPFVNPLSALQSVMNIHLGKAAKPSLPALDPMSMLFKMSNSLAEKAAVATPPPLQAKK-AEHLDRYFYHVNNDQPIDLTKGKSDKGCSLGSGLLSPTSTSPATSS--STVTTAKTS-AVVSFMSNSPLRENALSDISDMLKNLTESHTSKSSTPSSISEKSDIDGATLEEAEESTPAQKRKG--------------------RQSNWNPQHLLILQAQFAASLRQTSEGKYIMSDLSPQERMHISRFTGLSMTTISHWLANVKYQLRRTGGTKFLKNLDTGHPVFFCNDCASQIRTPSTYISHLESHLGFR---LRDLSKLSTEQINNQIA-QTKSPSEKMVTS-----------------SP-----EEDLGTTYQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLLFVSELEKQ------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CGV9-1", "uniprot_id": "TSH3_MOUSE", "id": "Q8CGV9-1", "name": "Teashirt homolog 3", "aln": "MPRRKQQAPRRAAAYVSDELKAAALVEDDVEPEEQAADGEPSAKYMCPEKE-LSKACPSYQNSPAAEFSSHEMDSESHISETSDRMADFESSSIKNEEE--TKEVQVPLEDTT------------------VSDSLEQMKAVYNNFLSNSYWSNLNLNLHQPSSEN--NGG-SSSSSSSSSSSCGSGSFDWHQSAMAKTLQQVSQN--RMLP---EPSLFSTVQLYRQSSKLYGSIFTGASKFRCKDCSAAYDTLVELTVHMNETGHYRD-DNHETDNNNPKRWSKPRKRSLLEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVTPVAAKIIPAARKKPSLELELPSSPDSTGGTPKAT---LSDASDALQKNSNPYITPNNRYGHQNGASYAWHFEAR----KSQILKCMECGSSHDTLQELTAHMMVTGHF-IKVTNSAMKKGKPIMETPVTPTITTLLD--EKVQSVPLAATTFTSP--SNTPASVSPKLAVEIKKEVDKEKAVPDEKPKEREK---PSEEEEKYDISSKYHYLTENDLEESPKGGLDILKSLENTVTSAINKAQNGTPSWGGYPSIHAAYQLPNMMKLSLGSSGKSTPLKPMFGNSEIVSPTKTQTLVSPPSSQTSPMPKTNFHAMEELVKKVTEKVAKVEEKMKEPEGKLSPPKRATPSPCSSEQSEPIKMEASSD---GSFKSQENSPSPPRDACKEASPSAEPVENGKELVKPLSGG-LSGSTAIITDHPPEQPFVNPLSALQSVMNIHLGKAAKPSLPALDPMSMLFKMSNSLAEKAAVATPPPLQAKK-AEHLDRYFYHVNNDQPIDLTKGKSDKGCSLGSGLLSPTSTSPATSS--STVTTAKTS-AVVSFMSNSPLRENALSDISDMLKNLTESHTSKSSTPSSISEKSDIDGATLEEAEESTPAQKRKG--------------------RQSNWNPQHLLILQAQFAASLRQTSEGKYIMSDLSPQERMHISRFTGLSMTTISHWLANVKYQLRRTGGTKFLKNLDTGHPVFFCNDCASQIRTPSTYISHLESHLGFR---LRDLSKLSTEQINNQIA-QTKSPSEKLVTS-----------------SP-----EEDLGTTYQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLLFVSELEKQ------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63HK5-1", "uniprot_id": "TSH3_HUMAN", "id": "Q63HK5-1", "name": "Teashirt homolog 3", "aln": "MPRRKQQAPRRAAAYVSEELKAAALVDEGLDPEEHTADGEPSAKYMCPEKE-LARACPSYQNSPAAEFSCHEMDSESHISETSDRMADFESGSIKNEEE--TKEVTVPLEDTT------------------VSDSLEQMKAVYNNFLSNSYWSNLNLNLHQPSSEK--NNG-SSSSSSSSSSSCGSGSFDWHQSAMAKTLQQVSQS--RMLP---EPSLFSTVQLYRQSSKLYGSIFTGASKFRCKDCSAAYDTLVELTVHMNETGHYRD-DNHETDNNNPKRWSKPRKRSLLEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVTPVAAKIIPATRKKASLELELPSSPDSTGGTPKAT---ISDTNDALQKNSNPYITPNNRYGHQNGASYAWHFEAR----KSQILKCMECGSSHDTLQELTAHMMVTGHF-IKVTNSAMKKGKPIVETPVTPTITTLLD--EKVQSVPLAATTFTSP--SNTPASISPKLNVEVKKEVDKEKAVTDEKPKQKDK---PGEEEEKCDISSKYHYLTENDLEESPKGGLDILKSLENTVTSAINKAQNGTPSWGGYPSIHAAYQLPNMMKLSLGSSGKSTPLKPMFGNSEIVSPTKNQTLVSPPSSQTSPMPKTNFHAMEELVKKVTEKVAKVEEKMKEPDGKLSPPKRATPSPCSSEVGEPIKMEASSD---GGFRSQENSPSPPRDGCKDGSPLAEPVENGKELVKPLASS-LSGSTAIITDHPPEQPFVNPLSALQSVMNIHLGKAAKPSLPALDPMSMLFKMSNSLAEKAAVATPPPLQSKK-ADHLDRYFYHVNNDQPIDLTKGKSDKGCSLGSVLLSPTSTAPATSS--STVTTAKTS-AVVSFMSNSPLRENALSDISDMLKNLTESHTSKSSTPSSISEKSDIDGATLEEAEESTPAQKRKG--------------------RQSNWNPQHLLILQAQFAASLRQTSEGKYIMSDLSPQERMHISRFTGLSMTTISHWLANVKYQLRRTGGTKFLKNLDTGHPVFFCNDCASQIRTPSTYISHLESHLGFR---LRDLSKLSTEQINSQIA-QTKSPSEKMVTS-----------------SP-----EEDLGTSYQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLLYVSELEKQ------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7C9-1", "uniprot_id": "A0ACD6B7C9_DANRE", "id": "A0ACD6B7C9-1", "name": "", "aln": "MPRRKQQAPRRSAAYVPEELKEAALLDEDVEGEDSALEEEPAMKYVCQDKDLLLKDRPGFHDSPPADFSSHEMDSESHLSESSDRMSDFESASVKNEEDSSAKEPLTSLSSTSSMMMTTTATPSSEEATPLGPDSLEQMKAIYTSFLTNSYWSSLNLNLSQQPPEKPPRSHSSSSSSSSSSSSCGSGGYDWHQTAVAKTLQNVSQNQSRLLHPASEPNLFSTVQLYRQSTKLYGSIFTGASKFRCKDCSAAYDTLVELTVHMNETGHYRD-DNHETDSEGTKRWSKPRKRSLLEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVTPVAAKIISSARKRAPIELELPSSPDSNGGTPKPS---LSDPNDLLQKTPNPYITPNNRYGHQNGASYAWQFESR----KSQILKCMECGSSHDTLQELTAHMMVTGHF-IKVTNSAIKKGKPIMESMSTTAPNPILTNEDKVQSVPLAATAFSPPPPAPPPPSISPAIMPMEIKKEEKEVECTRETNNNKDKKAAESETDEKFEVSSKYPYLTEEDLEESPKGGFDILKSLENTVTSAINKAQNGTPSWGGYPSIHAAYQLPNIMKLSLRNSGKSSPLKYMFSGEELLSPTKSQPLISPPSCQTSPFPKNNFHAMEELVKKVTEKVAKVEEKMRDPGARSSPLRRTTPSPCSSDAGESARGESPKER-RGAKTPETNGGGITHKESNGDALTKESLENGTDHVVKTPVSTLCSSTAIITDHPPEQPFVNPLSALQSVMNVHLGKAAKPALPSLDPMSMLFKMSNSLAEKAAVAASTPSQTKKTNDHLDRYFYHINNDQPIDLTKGKSDKSNSLGSAALSSSTSTPTSISPSSTITMAKASSAVASFMSNSPLRENALSDISDMLRNLTENHASKSSTPTSLSERSDIDGSTPEESEEISPAQKRKG--------------------RQSNWNPQHLLILQAQFASSLRQTGDGKYIMSDLSPQERMHISRFTGLSMTTISHWLANVKYQLRRTGGTKFLKNLDSGHPVFFCSDCASQIRSPSTYVSHLESHLGFR---LRDLAKLSGEHLVSQISRHTKGLSEKLLSAQAHSLAHTIANPSPHSLSPSPSPDEEANGTSYQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLMYVSELEKP------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22265-1", "uniprot_id": "TSH_DROME", "id": "P22265-1", "name": "Protein teashirt", "aln": "------------------MLHEALMLEIYRQALNAGALPTARPRSTESANSS--------ERCPSHDSNSSEHGGGAGSGGVGHRLDAAALSTGVMPGE---GPTTLHSSFPA------------------VPQSLPSQPPSMEAYLHMVAAAAQQYGFPLAAAAA------AGAGPRLPLPLANEAAAPFKLPPQASPTASSNNS--------------EALDFRTNLYGRAESAEPPASEGEEEEFDDGANNPLDLSVGTRKRGHESEPQLGHIQVKKMFKSDSPPANSVASPSASQLLPGVNPYLAAVAAANIFRAGQFPDWNSKNDLVVDPLEKMSDIVKGGASGMGTKEKMHSSKATTPQAASQPPKSPVQPTPNQNSESGGGSGGGAAGSGAVTKARHNIWQSHWQNK--GVASSVFRCVWCKQSFPTLEALTTHMKDSKHCGVNVPPFGNLPSNNPQPQHHHPTPPPPPQNHNLRKHSSGSASNHSPSANVKNAFQYRGDPPTPLPRKLVRGQNVWLGKGVEQAM-----QILKCMRCGESFRSLGEMTKHMQETQHYTNILSQEQSISIKSGNANAN------SDAKESHNSLSSEESRTLSAVLTCKVCDKAFNSLGDLS----NHMAKNNHYAEPLLQSAG----------ARKRPAPKKREKSLPVRKLLEMKGGSGTTQEDHSNE--KTSVQGKPGLGPGGGDKNDAALFAERMRQYITGVKAPEEIAKVAAAQLLAKNKSPELVEQKNGGSAKAAGASSVLSAIEQMFTTSFDTPPRHASLPASSPSNSSTKNTSPVASSILKRLGIDE-TVDYNKPLIDTNDPYYQHYRYTSSERSGSECSAEARPRLDAPTPEK--QQQGGGHDEES-----------------SKPAIKQEREAESKPVKMEIKSEFVDEPNEAEETSKMEAAVVNG-----------------------SATNNNNNIVERSSPKTPSSAASPQTRLLPPRSPAESQRSVTPKSPASSHKSYDGSSEGTKKFPSD----------------------------SLNALSSMFDSLGSSGAGANSRAKLAAAAAAGGS----ESPENLTAGG-------------------------NSLAALRQFCVKKEKTA------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9U3V5-1", "uniprot_id": "TIPT_DROME", "id": "Q9U3V5-1", "name": "Protein tiptop", "aln": "-----------------MMLHEAVMLEIYRQALSASELTSPRCQSRDSNTSAGAGAGMADVRCPSNESHCSANDRLTPAATPTLTPTEATISPNSVG-----LPLTATLPPAA------------------AVALLPPQSAAMAAYLAAAQQNHLLLTNPLAAAAS------LVQHATQQAVVEGEVESPALDFSRKRPKSHGDDD--------------QEEDQ--------EQDQEQEQEQEPDHDVQCDNGPLDLSVSTGKRQESVSPPARKIPRSISADYKSPLP-------PGSWMPPINPYLAAVAAK----TGGLGYSKLAPSEASKALEKMTEMSR---------------LETSPTAAR---------SLGATSSVGAGVPAGASSN---SGGRHSAWQSHWLNKGADTAKDVFKCVWCKQSFSTLANLTAHMKETQHCGVQIP--SPLPTGGVG-TPSAPPPTRLATSASNSACSSSSSSTSSSSNSSKSELNMLIKETMPLPRKLVRGQDVWLGKGAEQTR-----QILKCMWCGQSFRSLAEMTSHMQETQHYTNIISQEQIISWKSGDERERPTNTGVPSTSTAAPSSPSCTAPSVSAVLTCKVCDQAFGSLKELS----THMAQKSHYKESPAPSASPPAAGTGNPKRGRQNRNEKRKKSLPVRKLLELERSGSNSSLDSALKPLRDFAAATKITCEKCGSKIETALFVEHIRKCLG---ESIPIPPRRSNAGVDRLPSPSLG-------LGAEKPPSVLNALEQLIEKSFESRTSRTMTHGG-----YSEAGTPLGASILKRLGIED-SSDYTKPLMDAQAMHLLRSSFASRDRSASESSSASR-VESSYTPDR--QQATPHKSPDTPAPPPPPPPTIKAEPLEAEPLVGCDREGCSPRQQIQVKKEFSMEACRESPRSVSKSPAPQTERSPPDNGSLLALNSMFDQLSGVENSGNNNSGHCFNNNNSCSSVSAQKPKAHPLAALQKLCETTDPPSTGLRSASSAGSSTASATLPSANGNDLVAFSWACNEAVLSASNGGSAGDSSIIKCSYCDTPFASKGAYRHHLSKVHFVKDAGEDSPRLKSPAVQSPRS-------------------------MPLASPRRSASRSPATGSQQPPPSPTISPYDESPQSKFLKYTELAKQLSSKNA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: * ::: : . . : .. .*. : . . : . .. .: * . :* .. . .. . . .:. . : . .: . .. : ::*:* : . . . . ..* . : : . : . : * :: : ::* : . .. : . . : :: : ..:::*: * .*. ** **:** : * :::. . .. . . ::: :.. . :: : . :: : : ...: * * . . . : * *: :: .. . : : . .. :: ... . *.. :* : . . . . .: :.: * : . .. . : : . . . . .. . *.*.:: :: . . . : . .. . : .. . : : . : . ::. * * : :. . : : . : * : . . . : . : . : :. * . . : :* . . .. : . * :. . :*: . :. . .: : . . ", "identical_positions": 36, "similar_positions": 230, "identity": "3.04%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100322-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63HK5-1", "uniprot_id": "TSH3_HUMAN", "id": "Q63HK5-1", "name": "Teashirt homolog 3", "aln": "MPRRKQQAPRRAAAYVSEELKAAALVDEGLDPEEHTADGEPSAKYMCPEKELARACPSYQNSPAAEFSCHEMDSESHISETSDRMADFESGSIKNEEETKEVTVPLEDT--TVSDSLEQMKAVYNNFLSNSYWSNLNLNLHQPSSEKNNGSSSSSSSSSSSCGSGSFDWHQSAMAKTLQQVSQSR-MLPEPSLFSTVQLYRQSSKLYGSIFTGASKFRCKDCSAAYDTLVELTVHMNETGHYRDDNHETDNNNPKRWSKPRKRSLLEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVTPVAAKIIPATRKKASLELELPSSPDSTGGTPKATISDTNDALQKNSNPYITPNNRYGHQNGASYAWHFEARKSQILKCMECGSSHDTLQELTAHMMVTGHFIKVTNSAMKKGKPIVETPVTPTITTLLDEKVQSVPLAATTFTSPSNTPASISPKLNVEVKKEVDKEKAVTDEKPKQKDKPGEEEEKCDISSKYHYLTENDLEESPKGGLDILKSLENTVTSAINKAQNGTPSWGGYPSIHAAYQLPNMMKLSLGSSGKSTPLKPMFGNSEIVSPTKNQTLVSPPSSQTSPMPKTNFHAMEELVKKVTEKVAKVEEKMKEPDGKLSPPKRATPSPCSSEVGEPIKMEASSDGGFRSQENSPSPPRDGCKDGSPLAEPVENGKELVKPLASS-LSGSTAIITDHP-PEQPFVNPLSALQSVMNIHLGKAAKPSLPALDPMSMLFKMSNSLAEKAAVATPPPLQSKKADHLDRYFYHVNNDQPIDLTKGKSDKGCSLGSVLLSPTSTAPATSSSTVTTAKTSAVVSFMSNSPLRENALSDISDMLKNLTESHTSKSSTPSSISEKSDIDG-ATLEEAEESTPAQKRKGRQSNWNPQHLLILQAQFAASLRQTSEGKYIMSDLSPQERMHISRFTGLSMTTISHWLANVKYQLRRTGGTKFLKNLDTGHPVFFCNDCASQIRTPSTYISHLESHLGFRLRDLSKLSTEQINSQIAQTKSPSEKMVTSSPEEDLGTSYQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLLYVSELEKQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CGV9-1", "uniprot_id": "TSH3_MOUSE", "id": "Q8CGV9-1", "name": "Teashirt homolog 3", "aln": "MPRRKQQAPRRAAAYVSDELKAAALVEDDVEPEEQAADGEPSAKYMCPEKELSKACPSYQNSPAAEFSSHEMDSESHISETSDRMADFESSSIKNEEETKEVQVPLEDT--TVSDSLEQMKAVYNNFLSNSYWSNLNLNLHQPSSENNGGSSSSSSSSSSSCGSGSFDWHQSAMAKTLQQVSQNR-MLPEPSLFSTVQLYRQSSKLYGSIFTGASKFRCKDCSAAYDTLVELTVHMNETGHYRDDNHETDNNNPKRWSKPRKRSLLEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVTPVAAKIIPAARKKPSLELELPSSPDSTGGTPKATLSDASDALQKNSNPYITPNNRYGHQNGASYAWHFEARKSQILKCMECGSSHDTLQELTAHMMVTGHFIKVTNSAMKKGKPIMETPVTPTITTLLDEKVQSVPLAATTFTSPSNTPASVSPKLAVEIKKEVDKEKAVPDEKPKEREKPSEEEEKYDISSKYHYLTENDLEESPKGGLDILKSLENTVTSAINKAQNGTPSWGGYPSIHAAYQLPNMMKLSLGSSGKSTPLKPMFGNSEIVSPTKTQTLVSPPSSQTSPMPKTNFHAMEELVKKVTEKVAKVEEKMKEPEGKLSPPKRATPSPCSSEQSEPIKMEASSDGSFKSQENSPSPPRDACKEASPSAEPVENGKELVKPLSGG-LSGSTAIITDHP-PEQPFVNPLSALQSVMNIHLGKAAKPSLPALDPMSMLFKMSNSLAEKAAVATPPPLQAKKAEHLDRYFYHVNNDQPIDLTKGKSDKGCSLGSGLLSPTSTSPATSSSTVTTAKTSAVVSFMSNSPLRENALSDISDMLKNLTESHTSKSSTPSSISEKSDIDG-ATLEEAEESTPAQKRKGRQSNWNPQHLLILQAQFAASLRQTSEGKYIMSDLSPQERMHISRFTGLSMTTISHWLANVKYQLRRTGGTKFLKNLDTGHPVFFCNDCASQIRTPSTYISHLESHLGFRLRDLSKLSTEQINNQIAQTKSPSEKLVTSSPEEDLGTTYQCKLCNRTFASKHAVKLHLSKTHGKSPEDHLLFVSELEKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QL82-1", "uniprot_id": "F1QL82_DANRE", "id": "F1QL82-1", "name": "", "aln": "MPRRKQQAPKRAAAYDSENGKETVVQTEGTESVCPVTKENPQGENDLGED--FKNPMDEQDCSASELSGHDVDSESHISESSEPTSDAESTTIKNEEATKDFIKDSSENSVCITDSLEQMKAIYKSFLNNPYWSFLSLNSPQSYADEQPASSSGSSSSNSSPGRTCYDWHQSAIAKTLQQVSQKPPIALEPSIFSTVQLYRQSTKLYGSIFTGASKFHCKSCSAAYDTLLDLTVHMNETDHYRDDNLESASKSGKSWSKPRKRSLLEMEGKEDAQKVLRCMYCGHSFESLQDLSVHMIKTKHYQKVPLREPRTAIAAKVVSSFRKRVPVELDVAKSLHTTEQTRSPNEGHTRDILQMYSEQNIKDD---LDQKTTSRGVHFKS---QNLKCLECGISHDSLQQLSAHMMLTGHFLKVTQSLQKTDKTPHPKSKS---EKSLSETTCSSPLAATRILE-SSSYSSIATGDHKNKTQEITSQKSS---ESKESANVNDVRQKLGPSAKTDYLTEDDLKESPKMDFDILKSLENTVTSAINKAQKGAPSWGGYQSIHAAYQLRNHLKPALHNPGYISSLKQSSSSQEVQSLDKSN-LIPPSTQPSSSSTTVQVSEVDELEMNVTEKDAEVDRKLKDLNGQGSP--------------HPQLLNLKGKSLMLKSPSPESTVTSMSKITEGKTEEKETRKHKQDPTSTSNLYDDSSLLSAQPEPKQPSVSPLSALQSVMNLHLGKAAKPVRPVQDPMSMLLRMSNSMAERAALAGPS-GHSTKLSQLHSNCHEICRDQPIDLSKGKNEQ--YLTTASVPGKALSSSISGASVSESNSPKIFTPVS--PLHENALSDISDMLRNLSDSRVSKPPTLLCRPEQSEIEGSRTSEEAEDTSIVHKRKGRQSHWKPQHLLILQAQFTSCLRQTADGKYVISDLSSQERMVISHITGLSMTTISHWLANVKYQLRRTGRTKFIKNVDSGHPVFYCSECATQFQARSTYICHLESHLGFKMKDLAKITSKDINRKIPKH-SKSTPIKPALP---------------------------AVSPARGCQEQLLPVPAL---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********:***** *:: * :.: :. :. .:. :*..: *. : . *:..*:*:* *::********:*: :* ** :***** **:. .:. ::********:*:.**.*.*** *.** *. :::: .***.****.** * .:******:*********. : ***:**********:*************:**.********::********.****** *: .:. * **********************:*****************************:** *.:***::.: **: .:**::..* .:* * ... ..: * ** *: *. : .*: :* . **:: * ***:*** ***:**:*:****:****:***:* *..*. .. : . *.*.. * ***** : . *.: :*::. : .:*: .:*: :.*: : .: .:* . *:* .****:**:**** .:******************:*:****** ******** * :* :* ..* :.** ...*: * *.: *:.*.:. :*. ...:. ::** :**** *:*:.*:*: :*: ** .* :: .... : .. .. *. . .* . :* *. *. .* : . * ..::::: :* *:** *.**********:******** *. ******::****:**:**:* *. ::.* .:*. :.: .******:***.:: * : :. .: :.: *.::*: :::. :.: :* **:***********:**::*:.**..* . .*:*:*:* * ****::: .:*******:*:***********::.****::***::****.**** **::*********************** ***:**:*:*****:*.:**:*::: ****.********:::**:*:::::** :*.: * * : .: * : : .:. :::** *. * ", "identical_positions": 512, "similar_positions": 322, "identity": "47.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100326-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O15417-1", "uniprot_id": "TNC18_HUMAN", "id": "O15417-1", "name": "Trinucleotide repeat-containing gene 18 protein", "aln": "-MDGRDFGPQRSVHGPPPPLLSGLAMDSHRVGAATAG-RLPAS------GLPGPLPPGKYMAG-LNLHPHPGEAFLGSFVASGMGPSASSHGSPVPLPSDLSFRSPTPSNLPMVQLWAAHAHEGFSHLPSGLYPS-YLHLNHLEPPSSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGAPGSLHSHAPSARTPGGG---HSSGAPAKGSSS-RDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEGRQDRG-----------PPRLAERLSPFLAESKTKNAALQPSVLTMCNGGAGDVGLPALVAEAGR---------GGAKEAARQDEGARLLRRTETLLPGPRPCPSPLPPPP-APPKGPP----APPAATPAGVYTVFR---EQGREHRVVAPTFVPSVEAFDERPGPIQIASQARDAR---AREREAGRPGVLQA--------------PPGSPRPLDRPEGLREKNSVIRS--LKRPPPADAP-TVRATRASPDPR--AYVPAKELLKP----EADPRPCERAPRGPAGPAAQQAAKLFGLEPGRPPPTGPEHKWKPFELGNFAATQMAVLAAQHHHS-RAEEEAAVVAASSSKKAYLDPGAVLPRSAATCGRPVADMHSAAHGSGEASAMQSLIKYSGSFARDAVAVRPGGCGKKSPFGGLGTMKPEPAPTSAGASRAQARLPHSGGPAAGGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQKDSGGSGRLGPGLVDQERSLSLSNVKGHGRADEDCVDDRARHREERLLGARLDRDQEKLLRESKELADLARLHPTSCAPNGLNPNLMVTGGPALAGSGRWSADPAAHLATHPWLPRSGNASMWLAGHPYGLGPPSLHQGMAPAFPPGLGGSLPSAYQFVRDPQSGQLVVIPSDHLPHFAELMERATVPPLWPALYPPGRSPLHHAQQLQLFSQQHFLRQQEFLYLQQQAAQALELQRSAQLVQERLKAQEHRAEMEEKGSKRGLEAAGKAGLATAGPGLLPRKPPGLAAGPAGTYGKAVSPPPSP-RASPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSPPPASPPPTPGITRKEEAPENVVEKKDLELEKEAPSPFQALFSDIPPRYPFQALPPHYGRPYPFLLQPTAAADADGLAPDVPLPADGPERLALSPEDKPIRLSPSKITEPLREGPEEEPLAEREVKAEVEDMDEGPTELPPLESPLPLPAAEAMATPSPAGGCGGGLLEAQALSATGQSCAEPSECPDFVEGPEPRVDSPGRTEPCTAALDLGVQLTPETLVEAKEEPVEVPVAVPVVEAVPEEG----LAQVAPSESQPTLEMSDCDVPAGEGQCPSLEPQEAVPVLGSTCFLEEASSDQFLPSLEDPLAGMNALAAAAELPQARPLPSPGAAGAQALEKLEAAESLVLEQSFLHGITLLSEIAELELERRSQEMGGAERALVARPSLESLLAAGSHMLREVLDGPVVDPLKNLRLPRELKPNKKYSWMRKKEERMYAMKSSLEDMDALELDFRMRLAEVQRQYKEKQRELVKLQRRRDSEDRRE---------EPHRSLARRGPGRPRKRTHAPSALSPPRKRGKSGHSSGK-LSSKSLLTSDDYELGAGIRKRHKGS----EEEHDALIGMGKARGRNQTWDEHEASSDFISQLKIK--KKKMASDQEQLASKLDKALSLTKQDKLKSP-FKFSDSAGGKSKTSGGCGR-YLTPYDSLLGKNRKALAKGLGLSLKSSREGKHKRAAKTRKMEVGFKARGQPKSAHSPFASEVSSYSYNTDSEEDEEFLKDEWPAQ---GPSSSKLTPSLLCSMVAKNSKAAGGPKLTKRGLAAPRTLKPKPATSRKQPFCLLLREAEARSSFSDSSEE-SFDQDESSEEEDEEEELEEEDEASG--GGYRLGARERALSPGLEESGLGLLARFAASALPSPTVGPSLSVVQLEAKQKARKKEERQSLLGTEFEYTDSESEVKVRKRSPAGLLRPKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAGPEASDDDLWTRRRSERIFLHDASAAAPAP-VSTAPATKTSRCAKGGPLSPR--KDAGRAKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSEARAPHASSLTAAKRS-KAKAKGKEVK------KENRGKGGAVSKLMESMAAEEDFEPNQDSSFSEDEHLPRGGAVERPLTPAPRSCIIDKDELKDGLRVLIPMDDKLLYAGHVQTVHSPDIYRVVVEGERGNRPHIYCLEQLLQEAIIDVRPASTRFLPQGTRIAAYWSQQYRCLYPGTVVRGLLDLEDDGDLITVEFDDGDTGRIPLSHIRLLPPDYKIQCAEPSPALLVPSAKRRSRKTSKDTGEGKDGGTAGSEEP-GAKARGRGRKPSAKAKGDRAATLEEGNPT---DEVPSTPLALEPSSTPGSKK---------SPPEPVDKRAKAPKARP-----APPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLITMPATRPKPKKARAAEESGAKGP----RRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESE--------SSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKAT--KQAGKARPSAHSPGKKTPAPQ--PQAPPPQPTQPLQPKAQAGA--KSRPKKREGVHLPTTKELAKRQRLPSVENRPKIAAFLPARQLWKWFGKPTQRRGMKGKARKLFYKAIVRGKEMIRIGDCAVFLSAGRPNLPYIGRIQSMWESWGNNMVVRVKWFYHPEETSPGKQFHQGQHWDQKSSRSLPAALRVSSQRKDFMERALYQSSHVDENDVQTVSHKCLVVGLEQYEQMLKTKKYQDSEGLYYLAGTYEPTTGMIFSTDGVPVLC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80WC3-1", "uniprot_id": "TNC18_MOUSE", "id": "Q80WC3-1", "name": "Trinucleotide repeat-containing gene 18 protein", "aln": "-MDGRDFGPQRSVHGPPPPLLSGLAMDSHRVGAATAG-RLPSS------GLPGPPPPGKYMAG-LNLHPHP----------------------------------------------------GFSHLPSGLYPS-YLHLNHLDPPSSGSPLLSQLGQPSIFDTQK------DGFYLP---APGTLHAHTPSSRTPSG----HSSGGPAKGSS--REGTGKDRAGRGGDPPPLFGKKDPRAR-EEVSGPRGVVDLTQEARAEGRQDRG-----------SSRLAERLSPFLAEVKAK-GALQPSALSLCNG----VVDAGLVAELGR---------GGAKEVARQEENARLLRRAEALLPAARPCGSPLPPPPPLPPKGPP----APPSSTPAGVYTVFR---EPGREHRVVAPTFVPSVEAFDERVGPIQIASQARDVR---AREREPGRPGVLQG--------------PPGSPR-LERPEVLREKSSVIRS--LKRPPPSDGPPAARSSRSSPDAR--AYLPPKELLKP----EADPRPCERAPRGPSASAAQQAAKLFGLEPSRPP--GPEHKWKPFELGNFATTQMAVLAAQHHHASRAEEEAAVATAS--KKAYLDPGGAMPRASATCGRPGADLHSAAHGPGEASAMQSLIKYSGSFAREAVAVRPGGCGKKSPFGGLGTMKPEPTPTSAGPPRAQARLTHPGVPTAGGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQKDSGSSSRLGPGLGDQERTLSLNNVKGHGRTDDEC--DRARHREDRLLGTRLDRDQEKLLRESKELADLARLHPTSCAPNGLNPNLMVTGGPTLAGSGRWSADPAAHLATNPWLPRSGSTSMWLAGHPYGLGPPSLHQGMAPAFPPGLGGSLPSAYQFVRDPQSGQLVVIPSDHLPHFAELMERAAVPPLWPALYPPGRSPLHHAQQLQLFSQQHFLRQQELLYLQQQAAQALELQRSAQLVER-LKAQEHRTEMEEKISKRSLETTGKAGLSAAGPGLLPRKSAGLANGPAGSHGKAVSPPPSP-RASPVTSLKAKVIQKVEDVSKPPAYTYPATPSSHPSSPPPASPPPTPGLTRKEEAPENVVEKKDLELEKETPSPFQALFTDIPPRYPFQALPPHYGRPYPFLLQPAAASDADGLAPDVPLPADGPERLALSPEDKPICLSPSKIPEPPRDSPEEEQLADREVKAEVEDIEEGPTELPPLESPLALPVPETMVAVSPAGGCGGSPLEAQALSTAGPGCREPSEVSDFAQVAEPQIELPSKTEHRMTALELGTQLTPEPLVETKEEPVEVPLDVPMEEPTTEAGPEDSLPQPSLTEPQPSLELSDCDLPVPEGQCLNLEAQEAVPAPASTCYLEETHSESLLPGLDDPLAGMNALAAAAELPQARPLPSLGPG-VPAGEKLDTAPSLVLEHSFLQGITLLSEIAELELDRRGQEAADPEPNLVVRPSLESLLAASSHMLKEVLESPFSDPLKNLRLPRELNSNKKYSWMQKKEERMFAMKSSLEDMDALELDFRMRLAEVQRRYKEKQRELVKLQRRRDSGDRHE---------DAHRSLARRGPGRPRKRTHTLSALSPPCKR-KSHSSSGKGLSSKSLLTSDDYDLGAGIRKRHKGP----EEEQEALMGMGKARSRNQSWDDHDSSSDFMSQLKIK--KKKMASDQEQLASKLDRALSLTKQDKLKSP-FKFSDGPGGKPKTGGGCGR-FLTQYDSLLGKDRKALAKGLGLSLKPSREGKHKRASKARKMEGGFQARGQPKSVHSPFASEVSSQSYNTDSDEDEDFLKNEWSAQ---GPSSSKLTSSLLCGMVPKNSKPATGPKLTKRGLAGPRTLKPKVVTSRKQSFCLLLREAEARSSFSDSSEEDSFDQDDSSEEEEEELEEEEEDEEEEGIGSYRLGAGEQALSPSLEESGLGLLARFAASALPSPVVGPPLSVVQLEAEQKARKKEERQSLLGTEFEYTDSESEVKVPKQSAAGLLRTKKGVGEPGQSLAAPGPGSRASGPSSPDKAKLVSEKGRKARKIRGPKEPGFEAGPEASDDDLWTRRRSERIFLHDASAAVQAT-SNTAPATKPSRCGRGGAPSPR--KDTGRAKDRKDPRKKKRGKEAGSAATLPPPRVSTLP-DSRAPHPGALATAKRS-KAKARGKEAK------KENRGKGGAVSKLMECMAAEEDFEANQDSSFSEDEHLPRGGATERPLTPAPRSCIIDKEELKDGLRVLIPLDDKLLYAGHVQTVHSPDIYRVVVEGERGNRPHIYCLEQLLQEAIIDVRPASTRFLPQGTRIAAYWSQQYRCLYPGTVVRGLLDLEDDGDLITVEFDDGDTGRIPLSHIRLLPPDYKIQCAEPSPALLVPSAKRRSRKTSKDTGEVKEGAATGPQEATGGKARGRGRKPSTKAKADRAVVLEEGAAT---NEVPSAPLALEPISTPNSKK---------STPEPVDKRARAPKARS-----ISAQPSPVPPTFSSCPAPEPFGELPTPATAPLVTMPVTMPATRPKPKKARAAEGSGAKGP----RRPGEDDELLVKLDHEGVMSPKSKKAKEALLLREDPGPGGWPESTGLLSLGSYSPAVGSSEPKATWPKGLDGDLTQEPGPGLPLEDPGNSKNPDKAQAEQDGAEESETTSSSSSSSSSSSSSSSSSSSSSSSSSGSETEGEEDAEKNREDGRGAGGRTCSAASSRASSPASSSSSSSSSSSSSSSSSSSSSSSS----------------------------------TTDEDSSCSSDEEAAPAPAAGPSTQPALPTKVS--KPPSKARSSAHSPGKKAPTTTQPPPQPPPQPQQTLQPKTQAGAGAKSRPKKREGVHLPTTKELAKRQRLPSVENRPKIAAFLPARQLWKWFGKPTQRRGMKGKARKLFYKAIVRGKEMIRIGDCAVFLSAGRPNLPYIGRIQSMWESWGNNMVVRVKWFYHPEETSPGKQFHEGQHWDQKSGHSLPAALRASSQRKDFMERALYQSSHVDENDVQTVSHKCLVVGLEQYEQMLKTKKYQDSEGLYYLAGTYEPTTGMIFSTDGVPVLC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "X1WHA2-1", "uniprot_id": "X1WHA2_DANRE", "id": "X1WHA2-1", "name": "", "aln": "MMDGRDFGPPRSVHVPPP-ILSGLPMESHRLGAAAAAGRIPPSPGHLGAGHPAALHTGKYLSSAMNLHSHHSDAFPG---ASSPFLGGYVGASSAHGSSDPAFRAPNQASLQMAQLWASHSHEGFSHLPSSLYPSPYIPLGHLEHP--------QLSQHALFDSQK------EGFYLPGSVHSQSAMARSPVAHMPGSFSRERESLPPHKSSKESSRDVGKEKPCKSDLAHSLPRKE--REKPKEESRPHSVVDLTLDLKAEDERRVGNLERPAKTTEHARPFFHQHSPALSNTDTKPKQTNHSLLGNSGTSSGTPTRHQSTEQDRRDRDDETIRPGGHLSNDKQKRCDSVATSAGTLHVSYASPSSLQPSPSHLPPRLVSSGTYPPPHHMPPSMYPLYSTTKEPGKEHRVIAPTYVPSVEVYDERKGPIQIASQARDNKNDKSRERESHRSALQLGNERTLMDHGRSSVRSESPPHGDVKRDILREEGSIIRSNGLAMKKPLHLEMCTNKSGNSPDARDLTNTTSKHMIRTGLETESRSQERDRVQRSTHSFSGMDPSSLHTEQHPLKTLGSAEPKWKPFEMGNYATSHMAALAAQHNHGARGEEEG--------KQMYLDT-TSLHRPVGSSGSP--------DGHGEVSAMQSLIKYSGNFSSESGSR--HGSDSRSPFGGLGSLKLEAG--YPGVSRVQHLPPQQP------GKQLKKEPERPESAKSFGRDGSSSQGEAEVRHPPVGIAVAVARQRDNSSKSSSAS---DRDRPLLGGPIKGPIHTEEEQGDERPRHRDERLLSGRVEREQEKVLRENKELADYTQLHPPMVSASGLNPNLMVTGGPTLAGAGRWPADPASHLASHPWLSRPGAPSMWLSGSPYGLGPPSLHQALPPGYPPALTGSIPPPYQFARDPQTGQVVVIPTEHLPHYAEMLERG--PPLWSAMYPPAGSSLQHAHQLQLLSHQQLLRQHELYMIQHQTAQVMELQRNAQLVER-LNASQPRTDLDEKLDKRAAEVHKSSLSCIPTTTLHSRKPPPCSPTPSTSYSKALTPLPVPPLPSPVTALKSEERPKVEKSLPQQPYSHPSSPAPHSISPASASPSPTSSIRTKEES-VEVSEKEPLSLQKQPSTTFPSIYREIPPGYPYQSITAPFGSHYPYLLQPAAAADADGLAPDVPLPAETSEHLAIAADVKPQHLCSPVLVEPLQTSREPEPMEE--EGSTVFKKEPNLEDLKDDSIRLAPIITQDSSTPTDP------EAHPRTIATPSPEEDPEQEHGEDIKIKRTSLYETSRLDVERSASTETTDASTG-LVDYKSSSSYSDTHLVVCDVQPTKQP------LDLSDSLNPADLRDA-VPDSSTHLESKLDNLFLPNSGPPHLPPSSAAVAILP--EDPMAGMFALVTASELPQAGAMSILTDACSSRSELCTDVS--PLESTALEGMALLSQMAELEMQRQPR----DDTQAVIFCGLESLLEAGRQVLLEAIEC---EPQVIIRLPRELNPNKKYSWRQKKDEPMFS-KSSLEGMDAAEVDYRVRLAELQQRYKEKQRELVKLQRRRDKEEKRQQQQQHIQQQERNRSLARRGPGRPRKRKHGLCALSPPSSKLDSRCAKLS----RSVLYSEDSESGEVLRKRFRASNRDEEEEEEDGSSALKLKKKKKSWGEQEACSSFSHEVPKMAVKKSRVSEQEQLASKLDKALSLTKLNKFSKPSCKFIDGSSGKSRPSSGSRVPMLTDLDVRVKMGKSSLSKDLGIFQKTSKGGKSKTAAKTKPSEACLKGKGQRKAPYSPVRSEISSYSNNTDSEE-EDSLKDGWPSSSMLGRTGSHPQLPGLCSTPSKKKRSSS--KRASSSSSSSLKSKQAAKERKHKHFALLLQEAGVSS------SEDSFDQEYSTERDDSEDDDEDED-----GYDYELDESDGLCSSSVEESGLGLLARFAASAIPSPIITNPLSLVQLEAKQKAKKKEERQSLLGTEFEFTDSESDVKTRKKFPS-LLHGKR----SAPELPLLPPASVMRDDSSP------TKRGRKPKKPKSPREFSFDLTADGSEDEQWTRRRSERIFLHDAAQSTPISPSSKTPLPLTPKPARGPKTSPQSPKELVKAKEVKDPSKKKRIKET--PLCLPPPQLSSTPSETSGALPVSPGRKNKVQKPKAREELGQNVLEFPQQARGKGGAVSKLMESMAADEDFEPNQDSSFSEDENPSVSAQPERPCTPAPRNCVINKDELQDGLRVLIPMDDKLLYAGHVSTVHSPDIYSVVVEGERGNRPHIYCLEQLLQEAIIDVKPPSVRYLPQGTRIAAYWSQQYRCLYPGTVVRGSPDMEDVDDLITVEFDDGDTGRIPLSHIRLLPADYKIQCAEPSPALLVASTKRRGRKCSKDVPDGKETPPKITEES-APKSKGRGRKPKPKPEPEAAPKEHEKPDTPTPTQVPERPLSSQKSSPRPGRKIKQVGTASVSIPASNENQKKTTGIKPPAKVRSQPQSVYSQPLYGKVLSVDLYNEPSTSLASFISNNETSSPTGKGKTVKRLRKPEEEASGFGVKTQRKQPQTEILIKLDHEGVMSPKTKKTKALMMMEGQNLSK--RENKSVMGVSYTTISTTEKTIKAKSKPVEAEPPTAESVSTYSVRKLGSS-SEGLMKVSNSGKKEKK-----------DLECSSSSSSSSSESDGEEEQGATQEKKPKQD-------SASSISSRASSPTSSSSSTSSSSSGSHSSSSSSSSST----------------------------------TSDEESSCSSDEEPVADSQPSPAAEHVASPEEEDVKAKSGSAPNIHKLQKQSSTTQQRHQQKTPQRQQ----KVKQGVG---RPKRREGIHLPTTKELAKRQRLPSVENRPKISAFLPARQLWKWFGKPTQRRGMKGKAKKLFYKAIMRGKEMIRIGDCAVFLSAGRPNLPFIGHIQSMWESWGNNMVVRVKWFYHPEETNPGKKLHDKKNWDQMSGQSLPAVLQASNQRKDFMERALYQSSHIDENDVQTISHKCLVVSLEQYEQMIKTKKYQDSEDLYYLAGTYEPTTGMIFNTDGVPVIC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******** **** *** :****.*:***:***:*. *:*.* * *.. .***::. :***.* *******.**** *: *.**: * **.* ::**:** :***** . : :::* :: *.. :.* * *.*. . .*::. :.. . .* *: * : :* * *:.***** : :**..: * . : .: ** *:: .:* : * * .. . : * ** . :*.. : : :* . . * *.*. **: . .** *..:*.:: * *:****:***:*****.:*** *********** : :****. *..: . . ..*: : : ***:.*:*** * * . .. : ***.* : ..*.:::. *: .: :*. *.. . :. :.:.*. : . ..* ******:**:*:::**.*****:*. *.***. *: ***. : *. .:.* * .* **.***********.*: :: : *...:*******::* *. .* .*.* .: *:***::********:***:**.:********************:*..... .. *::*.* . :** ::::: :*.***::***. *::*:***:***.***** ::***. :..************:***:***.****:***::***.*.* .****:* ***********.:.*.:**.* **:*..***.****:**:****::****:**::**. ****.*:***. *.*:**:****:*:*::***:*: :*:*:**.:****.****:. *:*.: *::::** .**. *. .: . . . * .**.. : *: ::.**::* * * .***::**:: *:*. .*::*::*:.*. **..***.**..: ***: :* **: *.*:*:..:.* ::: :*** **:*::.. :* **:****:**:*************: .*:**::.: ** *... : ** : . * * : : : * . : . :* . *. .: : : . ..:::::.. .* : : .. : ..: : :* .: :. **: *... : : : . ::. . :: *. :* . : . : :* ... .: : :** :**:*** **.:*:***** .:. . * . ** : *.*::***::****::*: : : * .***** *. ::* *.:: :* :******:.****** :**:* *:: *****.*** *:*:*:****:*::****************. :::: : :**************.* .***** .: .* :. . :*:* *:* : * :***.:.. ***.: . * : ::::*.::::.*.* :: **. .*:*********:****** :*:..* ** *...**.:...*. ** * : .:.:*:*.**: *.*: ** * *:*:: * ::.:** *: :**. **:** * ****:* *: **: *.:. * :.*: . **. .*:.:.: * :. . :.. . * ::: *.***:** . * .* ****: *:*.::.* : *:** .*.*. : *..:***************:*** : .**:*****:***:**************:*****:**. *: .: **: *: .. .*. *.: . *** ::***.:* :.*:* .*: .:.*:*: **************: :. . ..:* . ..: .:* **: *: :**: *** ***: **: ****: .: * :: .. . : :: *.**: : : :: ************.***:****.**********: . .. *** *****.*:*:*:**:********:**********.******** ***************************:*.*.*:************************** *:** .************************.***************.*:***.** ***. : *: . .:*. . *::******..*.: : * .* * :**. **: : *. .:* * * . ::: ::. :. .*. * : . : : : * .:. :: : *: : *. * . *.* :* : *:*:******* ***:**:* :::. : . * ..::.:. . :. .. ** : *. . .... *.. . . :..:.* :*.: . ...********.*.*.* :* : .* :. ..*: ****:**:*****:*****.* *********: *:**:******:*... . ..*::: . ..: * . : .. *. *::.:. .** * *.: *. ***:***:***********************:*************************:*******:***********************:**:*************************.***::*: ::*** *.:****.*:.*.***************:*******:*******.*******:*********.****************.******:*", "identical_positions": 1278, "similar_positions": 849, "identity": "41.07%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100330-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UPT8-1", "uniprot_id": "ZC3H4_HUMAN", "id": "Q9UPT8-1", "name": "Zinc finger CCCH domain-containing protein 4", "aln": "MEAAPGTPPPPPSESPPPPSPPPPSTPSPPPCSPDARPATPHLLHHRLPLPDDREDGELEEGELEDDG--AEETQDTSGGPERSRKEKGEKHHSDS-DEEKSHRR-LKRKRKKEREKEKRRSKKRRKSKHKRHASSSDDFSDFSDDSDFSPSEKGHRKYREYSPPYAPSHQ----QYPPSHATPLPKKA-YSKMDSKSYGMYEDYENEQYGEYEGDEEEDMGKEDYDDFTKELNQYRRAKE-GSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRGRGRGSMGGDHPEDEEDFYEEEMDYGESE-EPMGDDDYDEYSKELNQYRRSKDSRGRGLSRGRGRGSRG-RGKGMGRGRGRGGSRGGMNKGGMNDDEDFYDEDMGDGGGGSYRSRDHDKPHQQSDKKGKVICKYFVEGRCTWGDHCNFSHDIELPKKRELCKFYITGFCARAENCPYMHGDFPCKLYHTTGNCINGDDCMFSHDPLTEETRELLDKMLADDAEAGAEDEKEVEELKKQGINPLPKPPPGVGLLPTPPRP-PG----------PQAPTS---PNGRPMQG-------------------GPPPPPPPPPPPPGPPQMPMPVHEP--LSPQQLQQQDMYNKKIPSLFEIVVRPTGQLAEKLGVRFPGPGGPPGPMGPGPNMGPPGPMGGPMHPDMHPDMHPDMHP------------DMHADMHADMPMGPG-MNPGPP-MGPGGPPMMPYGPGD-SPHSGMMPP--IPPAQNFYENFYQQQEGMEMEPGLLGDAEDYGHYEELPGEPGEHLFPEHPLEPDSFSEGGPPGRP-KPGAGVPDFLPSAQRALYLRIQQKQQEEEERARRLAESSKQDRENEEGDTGNWYSSDEDEGGSSVTSILKTLRQQTSSRPPASVGELSSSGLGDPRLQKGHPT--GSRLADPRLSRDPRLTRHVEAS---GGSGPGDSGPSDPRLAR--ALPTSKPEGSLHSSPVGPSSSKGSGPPPTEEEEGERALREKAVNIPLDPLPGHPLRDPRSQLQQFSHIKKDVTLSKPSFARTVLWNPEDLIPLPIPKQDAVPPVPAALQSMPTLDPRLHRAATAG-----PPNARQRPGASTDSSTQGANLPDFELLSRILKTVNATGSSAAPGSS-----------DKPSDPR-VRKAPTDPRLQKPTDSTASSRAAKPGPAEAPSPTASPSGDASPPATAPYDPRVLAAGG-------LGQGGGGGQSSVLSGISLYDPRTPNAG---GKATEPAADTGAQPKGAEGNGKSSASKAKEPPFVRKSALEQPETGKAGADGGTPTDRYNSYNRPRPKAAAAPAATTATPPPEGAPPQPG-------------VHNLPVPTLFGTVKQTPK-TGSGSPFAGNSPAR--EGEQDAASLKDVFKGFDPTASPFCQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZPZ3-1", "uniprot_id": "ZC3H4_MOUSE", "id": "Q6ZPZ3-1", "name": "Zinc finger CCCH domain-containing protein 4", "aln": "MEAVPGTPPPPPSESPPPPSPPPPSTPSPPPCSPDGRAATPHLLHHRLPLPDDREDGELEEGELEDDG--AEEVQDPPGGQERSRKEKGEKHHSDS-EEEKSHRR-LKRKRKKEREKEKRRSKKRRKSKHKRHASSSDDFSDFSDDSDFSPSEKSHRKYRDYSPPYAPSHQ----QYSSSHNAPLPKKS-YSKMDSKGYSMYEDYENEQYGEYEGDEEEDMGKEDYDDFTKELNQYRRAKE-GSSRGRGSRGRGRGYRGRGSRGGSRGRGMGRGSRGRGRGSMG-EHPEDEEDLYEEEIEYGESE-EPMGDDDYDDYSKELNQYRRSKDSRGRGLSRGRGRGSRGGRGKGMGRGRGRGG-RGGMSKGGMNDDEDFYDDDMGDGGGGSYRRSDHDKPHQQSDKKGKVICKYFVEGRCTWGDHCNFSHDIELPKKRELCKFYITGFCARAENCPYMHGDFPCKLYHTTGNCINGDDCMFSHDPLTEETRELLDKMLADDAEAGAEDEKEVEELKKQGINPLPKPPPGVGLLPTPPRP-PG----------PPAPTS---PNGRPMQG-------------------GPPPPPPPPPPPPGPPQMSLPTHEP--LSPQQLQQ-DMYNKKIPSLFEIVVRPTGQLAEKLGVRFPGPGGPSGPMGPGPNMGPPGPMGGPMHPDMHPDMHPDMHPDMHPDMHPDMHPDMHPDMHPDMPMGPG-MNPGPP-MGPGGPPMMPYGPGD-SPHSGMMPP--IPPAQNFYENFYPQQEGMEMEPGLVGDAEDYGHYEELPGQPGEPLFPEHPLEPDSFPEGGPPGRP-KAGAGVPDFLPSAQRALYLRIQQKQQEEE-RARRLAESSKQDRENEEGDTGNWYSSDEDEGGSSVTSILKTLRQQTSSRPQASVGEPSSSGLGDPRLQKGHPT--GSRLSDPRLSRDPRLSRHAETS---GGSGPGDSGPSDPRLAR--ALPTSKAEGSLHSSPAGPSSSKGQ--PPAEEEEGERALREKAVNIPLDPLPGHPLRDPRSQLQQFSHIKKDVTLSKPSFARTVLWNPEDLIPLPIPKQD-VPPVPAALQSLPALDPRLHRSTPPG-----PPNTRQRPGS-TDPSTSGSNLPDFELLSRILKTVNVN----TPGQS-----------EKPSDPR-VRKTPTDPRLQKPADPVAASRAAKPCPTEASPPAASPSGDSSPPATAPYDPRVLAAGG-------LGQGSSSGQSSVLSGISLYDPRTPNAG---GKTAEPASDTSAQPKGPEGNGKGSASKAKEPPFVRKSALEQPETGKASTDGATATDRYNSYNRPRPKATAAPTAASSTPPPEGATPQPG-------------VHNLPVPTLFGTVKPAPK-TGTGSPFAGNSPAR--EGEQDAGSLKDVFKGFDPTASPFCQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FGZ9-1", "uniprot_id": "E7FGZ9_DANRE", "id": "E7FGZ9-1", "name": "", "aln": "--------MAVESMTVHPNSP------------------TANHEHNSLLTDERQEDGELEEGELEDDGGEAEVPSGEVADPQDKPRHSKERHASESNDEEKSHRRRRKRKREREREKEKRRAKKKRKSKHKRHQSSSDEYSDYSDESDYSPSEK--RKYREYSPPYPPTSQGGYSSAPSGHGGPMSKKGGYMKIDKQGYGGYDDYEEETY---EGEDDEDMGDDDYDDFAKELNQYRKAKEVGGPRGRGGKNRMKNLRGRG-RGGMRGRGGRGGGRGRGRGKMG-GENDDGDGMYGEDMEYGDDDYDNMGDDDYDDYSKELNQYRKTKD-RGRGGKGGRGR-GRGKGGRGMNRGRGRNRGRGRGGDQGP-DDDNSGDKDMD--GSGPPRRNDQEK--HGPEKKGKAICKYYIEGRCTWGDHCNFSHDIELPKKKELCKFYITGFCARAENCPYMHGDFPCKLFHTTGNCVNGEECMFSHDSLTEDTQELLDKMLAEDAEAGAEDEKEVEELKKQGINPLPKPPPGVGLLPTPPRPSPGDSSTPMEFGMPSAPHGNIPPSGPPAPGPGVGPVPGPGPGPGPGPGIGPCPVPPPPCTDGGTFQGPPPTGPPPPMGPPPVCG-GNAGKKIPSLFEIVVKPTGQLAQKLGVRGPVPANASAGT-AGPQGPPPGPPGAP--PPRFPPPPGHMGP---------------GGPHERPPMGPSNMNQGPPSMGTGPPMMQNFVQGEGPPNPGMMSPGAGSAGNNFYDNFYQQQQAMSID----GSGRDCDNFQGMGGGNFNDQSPGN-HNSGSMESGANVGPSNQTGMAVPDFLPPAQRVLFMRLQQKQQEDEERARRLADGGGTERENEGGDSANWYSSEDEDGGGSVTSILKTLRQQTQNQGPAKPDGAPS----DPRLQKSQPTPAPSRPADPRLARDPRLSRNTDSSQAPEASSSLSPTPSDPRLARHAAAHASKPEPPLVYKPPPLTAPASN-----EEEEGERMLRDKPVPIPLDPLMGMALRDPRSQLQQFSHIKKDVVLQKPSFSKAVLWSPEDLIPIPIPKQD-LLPLPPGIPPVTTIDPRLSRTQPPHHSSILPPTVVPPPAPVEQSNQSSSSLPDFELLSRILKTVNASSSSPVQGASTGISSPPSVSSEKPIDPRMARKTPADPRLQP--QKSALKTTSEPLVPQGSPPTSSLSPPSSSPTIAPYDPRLLSAGGSVRSVGSASVGSSSGGTSVLSGISLYDPRSQGADKTEGSVATRNSSPPPEPKSSESTTASAKPKSKEPLFVRKSALDQPEPEKSSTE--QTTDRYNSYNRPRPKPSPSPNAGTAAAPTATSGPSTAGQGTTVSAEQPAAVHNLPVSTLFTMVKQVNKPSGTGSPFGGSSPAQPDTAEQDNASLKDVFKGFDPTASPFCQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : * ** *.: *: * : :************** ** .. .. : . :.. *:* *:* :******* ****::********:**:******** ****::**:**:**:***** ****:*****.*: * . ...* *:.**. * *:*.:.*. *:***:* * **:::****.:*****:*******:*** *..****.:.* :. **** *** **** *.******.** . :* :.:* *:::**:.: : *******:*********::** **** . **** .** *:**.*****. ** .. * **:: *.**. *.*. * *::* : .:****.****::*********************:****************************:******:**::******.***:*:********:*************************************** ** * ** . *.* * * ** * **** . *. * . *. * :.* : . .***********:******:***** * *..... .**: **** *.* * .* .* * . * ****. ** *** **.* * * : *: .*:.***.* ...:***:*** **:.*.:: *...* .::: : * : * : :..*: .*. * . :.* .******.***.*::*:******:* ******:.. :**** **:.*****::::**.*************..: *. . .* ******.:** ** :****:*****:*:.::* .*.. .. ******** * :**.* .* .* ::. .. ******* **:*.* ****** * .******************.*.****:::***.******:****** : *:*..: .:.::**** *: .. **.. *.. :.. ..:.***************.. . * * :** *** .**:*:***** : * . :::* .:...*::* * :*.*: ******:*:*** . *...* :************: .*. *..: :.. .:**..*.. .: .*:*** *******:***. *:.:: .*************.:.:* * :::.*. : *... ******.*** ** . * :*:****.*.***: .*** .******************", "identical_positions": 708, "similar_positions": 325, "identity": "49.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100330-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A6T9-1", "uniprot_id": "D4A6T9_RAT", "id": "D4A6T9-1", "name": "MAP/microtubule affinity-regulating kinase 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MSSRTALAPGNDRNSDTHGTLGSGRSSDKGPSWSSRSLGARCRNSIASCPEEQP---------------------------------------------------HVGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINIGYEGEELKPYTEPEEDFGDTKRIEVMVGMGYTREEIKEALTNQKYNEVTATYLLLGRKTEEGGD---RGAPGLALARVR--------APSDTTNGTSSSKGSSHNKGQRTSSSTYHR-QRRHSDFCGPSPAPLHPKRSPTSTGDTELKEER-LPGRKASCSAAGSGSRGLPPSSPMVSSAHNPNKAEIPERRKDSTSTPNNLPPSMMTRRNTYVCTERPGSERQSLLPNGKENSSGTSRVPPASPSSHSLAPP------SGERSRLARGSTIRSTFHGGQVRDRRAGGGSGGGVQNGPPASPTLAHEAAPLPSGRPRPTTNLFTKLTSKLTRRVTDEPER--IGGPEVTSCHLPWD---------------------------------------KAETAPRLLRFPWSVKLTSSRPPEALMAALRQATAAARCRCRQPQPFLLACLHGGAGGPEPLSHFEVEVCQLPR--PGLRGVLFRRVAGTALAFRTLVTRISNDLEL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIP4-1", "uniprot_id": "MARK4_MOUSE", "id": "Q8CIP4-1", "name": "MAP/microtubule affinity-regulating kinase 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MSSRTALAPGNDRNSDTHGTLGSGRSSDKGPSWSSRSLGARCRNSIASCPEEQP---------------------------------------------------HVGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINIGYEGEELKPYTEPEEDFGDTKRIEVMVGMGYTREEIKEALTNQKYNEVTATYLLLGRKTEEGGD---RGAPGLALARVR--------APSDTTNGTSSSKGSSHNKGQRASSSTYHR-QRRHSDFCGPSPAPLHPKRSPTSTGDTELKEER-MPGRKASCSAVGSGSRGLPPSSPMVSSAHNPNKAEIPERRKDSTSTPNNLPPSMMTRRNTYVCTERPGSERPSLLPNGKENSSGTSRVPPASPSSHSLAPP------SGERSRLARGSTIRSTFHGGQVRDRRAGSGSGGGVQNGPPASPTLAHEAAPLPSGRPRPTTNLFTKLTSKLTRRVTDEPER--IGGPEVTSCHLPWD---------------------------------------KTETAPRLLRFPWSVKLTSSRPPEALMAALRQATAAARCRCRQPQPFLLACLHGGAGGPEPLSHFEVEVCQLPR--PGLRGVLFRRVAGTALAFRTLVTRISNDLEL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96L34-1", "uniprot_id": "MARK4_HUMAN", "id": "Q96L34-1", "name": "MAP/microtubule affinity-regulating kinase 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MSSRTVLAPGNDRNSDTHGTLGSGRSSDKGPSWSSRSLGARCRNSIASCPEEQP---------------------------------------------------HVGNYRLLRTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMKEKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGHNLKELRERVLRGKYRVPFYMSTDCESILRRFLVLNPAKRCTLEQIMKDKWINIGYEGEELKPYTEPEEDFGDTKRIEVMVGMGYTREEIKESLTSQKYNEVTATYLLLGRKTEEGGD---RGAPGLALARVR--------APSDTTNGTSSSKGTSHSKGQRSSSSTYHR-QRRHSDFCGPSPAPLHPKRSPTSTGEAELKEER-LPGRKASCSTAGSGSRGLPPSSPMVSSAHNPNKAEIPERRKDSTSTPNNLPPSMMTRRNTYVCTERPGAERPSLLPNGKENSSGTPRVPPASPSSHSLAPP------SGERSRLARGSTIRSTFHGGQVRDRRAGGGGGGGVQNGPPASPTLAHEAAPLPAGRPRPTTNLFTKLTSKLTRRVADEPER--IGGPEVTSCHLPWD---------------------------------------QTETAPRLLRFPWSVKLTSSRPPEALMAALRQATAAARCRCRQPQPFLLACLHGGAGGPEPLSHFEVEVCQLPR--PGLRGVLFRRVAGTALAFRTLVTRISNDLEL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B3S3-1", "uniprot_id": "A0A8M2B3S3_DANRE", "id": "A0A8M2B3S3-1", "name": "MAP/microtubule affinity-regulating kinase 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------MSSRAALQPGNDRNADHHATLSASRS-EKGSGWSSRSLGARCRNSIASCSDEQP---------------------------------------------------HIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQLNPTSLQKLFREVRIMKGLNHPNIVQLFEVIETEKTLYLVMEYASGGEVFDYLVSHGRMKEKEARGKFRQIVSAVHYCHLKNIVHRDLKAENLLLDADSNIKIADFGFSNEFTLGSKLDTFCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSLPFDGQNLKELRERVLRGKYRVPFYMSTDCEGILRRFLVLNPTKRCTLEQIMKDKWMNVGYENDELKPYIEPVEDYNDTSRVDVMVGMGYSRDEIKDALTTQKYNEIFATYLLLGRKNEDGMES--RSSSSLSLARVRPSAITNGTSKHSSTSSSSSTSASSHTKPQR-SASTYHR-QRRHSDFCGPSVPVAHPKRSPTSTGEGDLKEER-LPSRKTSSSVVGS--RSIPPSSPMVSTANNPNKSEIPDRRKDINATTNNIPASAMTRRNTYVCTDRTGTDRHSLLQNGKENSSLSHRLPPASPSTHSISGAGASSSTSSERSRLTRGSTIRSTFHGGQLREHRP-------PTHAPPTSPTLSHEASPLPHSRSRATTNLFTKLTSKLTRRVNLDPSKRQSSNKSVSGCTLPQGSKTVRSQTNLRESADLRSQATDTATKSQAKKHSRYLSGYQKATEPRTPRCGWDVRVRSPRDPAEVVLALREAAQGCGCQVHQAGPFLLSCTHGAAG---SRVAFEAEVCQLPNGPTESSGVRFKRLWGAPLAFRDIAAKVSKELEL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZBL9-1", "uniprot_id": "A1ZBL9_DROME", "id": "A1ZBL9-1", "name": "MAP/microtubule affinity-regulating kinase 3", "aln": "MSTAMRTTLQSVPEALPADSVSNGTASNVAAPAAPVSSATNAVPPLAAVSSTTATYATNSISTSSHSVKDQQQQQQQQQHDSANANIVSLPPTTTPVANTNTMMPIVTSSNSATSNSTAATPTPASGAAATGGVGSVSQGPATVSASAANTNHSHQHSHQHHHHVANNMTTDGARLSSNNSAVVASSAINHHHHHTPGSGVAPTVNKNVLSTHSAHPSAIKQRTSSAKGSPNMQMRSSAPMRWRATEEHIGKYKLIKTIGKGNFAKVKLAKHLPTGKEVAIKIIDKTQLNPGSLQKLFREVRIMKMLDHPNIVKLFQVIETEKTLYLIMEYASGGEVFDYLVLHGRMKEKEARVKFRQIVSAVQYCHQKRIIHRDLKAENLLLDSELNIKIADFGFSNEFTPGSKLDTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGSTLRELRERVLRGKYRIPFYMSTDCENLLRKFLVLNPAKRASLETIMGDKWMNMGFEEDELKPYIEPKADLADPKRIEALVAMGYNRSEIEASLSQVRYDDVFATYLLLGRKSTDPESDGSRSGSSLSLRNIS-------GNDAGANAGSASVQSPTHRGVHRSISASSTKPSRRASSGVGPTNAAATVAAATGAVGAVNPSNNYNAAGSAADRASVGS---NFKRQNTIDSATIKENTARLAAQNQRPASATQKMLTTADTTLN---SPAKPRTATKYDPTNGNRTVSGTSGIIPRRSTTLYEKTS------STEKTNVIPAETN--LFDRLRMASAVK------SSRHFPRNVPSRSTFHS--GQTRARNNTALEYSGTSGASGDSSHPGRMSFFSKLSSRFSKRPTIA--------------------------------------DEAAKPRVLRFTWSMKTTSPLMPDQIMQKIREVLDQNNCDYEQRERFVLWCVHGDPN-TDSLVQWEIEVCKLPR--LSLNGVRFKRISGTSIGFKNIASRIAFDLKLXLNQTNNEGNAAATASRPTDPTDTMTTTNCRRPSNDSTSRLSELSLLCRSLTSQQGSQRRKKSRLSTGGSEDQKKSNSLLSAFQMYSPFSSKENMQSSEEVEDLHVIDTQPGHSVDVPLFADFSPINPIMEEDAEGVEGGKTSEAKVISGGSGQKVKGDGGGGGGGNRLKRNIKHTGSLIVRKLTAGRHNDADKKGAIRKKDKEQQEVADTDKERPTSKPEGKVAMLRTTTL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: :. ..:::. * :.. .*. **.. .. . .:* .. * *:*:*:*::*************:*: **:************** ************* *:*****:**:**********:*****.******** ********** *********:*** *.*:************:: ************** ******************************:******************* .*:************:*********.:**:******:**.:** ** ***:*:*:* :***** ** * *..*::.:*.***.*.**: :*: :*::: *********. : . *....*:* .: .:. .::* ...:* :* ::: : .** *. **: . :. :.* : .:: .. :. : .** .: ...: *:: : *.:.:. :.: ::.::: .: * * .. :. : **:.. * : : * .:: . * *::.: ..* *. :: . : * *: : : *.* .* * . ** : . . . * . : ** * *.:: *. * :: :*:. * .* *:* * ** .. . :* ***:**. ** *:*: *:.:.*: :.:::: :*:* ", "identical_positions": 317, "similar_positions": 209, "identity": "25.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100402-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VQT0-1", "uniprot_id": "Q9VQT0_DROME", "id": "Q9VQT0-1", "name": "", "aln": "------MTTCLRSGVLIIVLLGILGIPEPISAGNILAVYPHFGFSHFKVVMPILNELAHRGHDITVISYVKNPQAGA-------YPNYEELLISAPGEDQSSTTINLVPLTEHTPTRSLGVLIREYVDLHEEGQKTCEHLFASGHIERAIERHRNK-PYDLLLTEYFNSDCQLALAKLLNLPIIGLSTCALMPYYYDRIDLPDTPAFIQSEFVGFAG---QLNWHERLLNFVQAKLLKFLYKYHSNRADNELVRKYLG-------------------------------------------VEVDVEEVARTQTAFIFGNQHYSLM-GSRPQSLQFVEIGGVHITKKA-EQELPQNIANFLNQS-AEGVIFISWGSMVRASSIDEDKLSAILEVLKSQPL---KIIWKWEADETPDTDASKFLFVKWAPQLALLCHPKVKLFWSHGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNRGMGLKLD-YQDITVPNLKKALAELSKN-SYAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIAARLLQSPGIELNGFVYHSLDSVALILLPLILLILVLCYLCKRNPSKLAHKKVGKKPKRS---------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJ46-1", "uniprot_id": "Q9VJ46_DROME", "id": "Q9VJ46-1", "name": "UDP-glucuronosyltransferase", "aln": "-----MWSPRVALLFLALALSQPDELVEAAGPLKVLGLFPHPGVSHFHFFHPIMKGLAEAGHDVSVVSHFPDKHP---------VAHYKDFPLTG--MDKLTNSVDLK----FFEKRTFYSHFQEFFLLYDWGKQTCNLTLRSEALQQILRRPGR---FDVIIMEQFNTDCMMGVAHQLQAPVIALSSCVMMPWHYERMGAPLIPSHIPALFMAQSQ---HMNFGGRLANWFSTHALNWMYKLLSVPAADAMVQYKFG-------------------------------------------HDVPSVGELVKNTSMFFVNQHYSLS-GPKVTPPNVIELGGIHIQK---SKPLPADLQRILDNA-EEGVILISWGSMIRANSLSAAKRDGIIRAVARLKQ---KVIWKWENETLPN-QPPNMHIMKWLPQRDILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPMYGDQFVNTAALVERGMGTILN-FEDIGENTVMRALKKALDK-KFHDAAKVVSHSFHHRPQQALHTAIWWVEHVAHTG--GAPLLKPSAVEMSRFVYYSLDVYAVLALVLGSIIASWVWLLRLCCGSSAAQKTKKD-------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2J4-1", "uniprot_id": "Q9W2J4_DROME", "id": "Q9W2J4-1", "name": "UDP-glucuronosyltransferase", "aln": "-------MSLKSALHIFLLSLVALQQLELGTGSRILAAFFFPGKSHFMMTNAIIRELVKQGHEVTFITPFSLAKEKL-------GSNYKEIVIP---QYDFWPEIKEMTNKNTVLEMTDLPTFAFLRMVNVMGIHTTDFALEQPEIQAVINEKNKIGKYDLLLAEQFFNEGALILGHLYQIPTITISTFGNANHLSQLFGVVSPWSYVPHAYMPYTD---RMTLWERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFS----------------------------------------KLLDRVPTIKELERNISAILLNSYMPLA-SSRPMAYNMIPVGGLHIQPPK---ALPEHLQKFLDGA-THGAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQ---RVLWKFEDESLPN-LPANVKVQSWLPQGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKSAEYALGLD-YRKVTVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHR--GAPHLVAAGVHLPWYQFYLLDIVGLGLAVILLPIVVLILICR-----RSSKPKSTPTKKKTKKN-----------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDA5-1", "uniprot_id": "Q9VDA5_DROME", "id": "Q9VDA5-1", "name": "UDP-glucuronosyltransferase", "aln": "--------------MILFMKLLFVCLLGTGDGARILAPFFLPVKSHFMMTDAIIRELVKRGHEVTFITPLSLAKENL-------GPNYREILLP---KYDTWADISAMMKTKSALDMIDMSKLTHMRLAQHIGIKSTDFALAHPEVQELIYAKDKKGKFDLLLVEQFHNEGALMLGYIYEIPAITIATFAYANYFSQVFGFVNPLSYVPNVFLSCTD---RMSLWERLENVVISTAEDVVREVSYYPQQDAVIRKHFS----------------------------------------SLLPRVPTVKQLEQNISVILLNSYMPLT-SPRPMSQNMISVGGLHILPPK---PLPEHIKNYLDNA-EHGAIYFSLGSQVRSADMPAEKLQIFLDVFASLKQ---RVLWKFEDDQLPN-LPDNVKVEKWLPQADILAHPNVKVFIAHGGLFGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGLD-YRTISKDQLKSALHALLKDPKYQANMMKASRIFRDRPLGAMDTAMYWINYVVEHR--GAPHLVAAGVHLPWYQFYLLDVSAIILAITLLPLLTLYAVSR-----NYKSFRGIRAQKKEAKTE----------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2J3-1", "uniprot_id": "Q9W2J3_DROME", "id": "Q9W2J3-1", "name": "UDP-glucuronosyltransferase", "aln": "--------MQFPLLFGLLLTGTLYSQLELAEGSKILAVYAFPGKSHFMMHTALIRELVESGHQVTMVTAFSLEKEQL-------GSNYTEILIEP--VYDFWHDVKLNFGAQHLFELTRMTNYDFLKMLEIIGLKTTEHALRQPKVRSLIHAEQKEGVFDLLLAEQFYQEAFLALAHLYKIPVVTTSTLGYENHMSQMMGLITPWSFVPHGFMPFTD---RMSFLERVKNSYASFYEDMDRLLNYFPKMDAVAREFFG----------------------------------------PVLTEVPKVKHMERQISVMLLNSHAPLT-TARPTVDAMVPVGGMHIYPPK---PLPADMQALLDGA-TEGAIFFSLGSNVQSKDMPVEMLRLFLQVFGSLKQ---RVLWKFEDESISQ-LPDNVMVRKWLPQADILAHRHVKVFITHGGLFGTQEGVHYAVPMLGIPFYCDQHLNMNKAVLGGYAISLH-FQSITEEILRHSLDQLIHNVTYKENVQRVSDIFRDRPLEPRKSAVYWIEYVIRHR--GASHMRSAGLDLNWFQFYLLDVIAFVAIIALAGVMALSLAIR-----LLMG--SNKKHRKAKQN-----------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJ81-1", "uniprot_id": "Q9VJ81_DROME", "id": "Q9VJ81-1", "name": "UDP-glucuronosyltransferase", "aln": "--------MEMQLQWKCWMLIFLIGLLEFGAGSRILFMGPFPAPSHWLWLEHFQNDLLRQGHHVTSVN--NHPTKHP-------HENLTEIIIS------PSFDIPKHFPKENIFSMQFVSDFNNLELWWTIGLMTTEHAFKDPKVKKLIESKDD--HYDLVIIEQFFHEAFLMFGKRFNCPVVTIGTMGYADNIDHAMGILTPWSLIPHLLLSHTD---RMTFGQRAYNAYLSLYDAVMRRWVYLPKMQKLAEKYFQG---------------------------------------SIEGPLPNVLDLERNISLVLINAHRSID-LPRPSMPGLIDVGGAHIQKPK---QLPTDLQNFLDNA-TYGVIYFSMGSYVKSTDLPQEKTALILKAFGQLKQ---QVIWKFENDSIGD-LPSNVMIKKWMPQNDILAHPNVKLFITHGGIFGTQEGIYWGVPMLCVPLYGDQHRNTIKSVREGYARSLV-FSKLTTDDLVRNIETLINDPQYKRSALEVSQRFRDNPIHPLDEATFWIEYIIRHR--GARHLKSHGAFIPLHQYLLLDVLGCLLLGAFLAIWLPWRMIRRVHKWWLKGESSNKLNEGKKRL-----------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT2-1", "uniprot_id": "Q9VGT2_DROME", "id": "Q9VGT2-1", "name": "UDP-glucuronosyltransferase", "aln": "------------MLASGLFYLIILLFPGFLYGARILALFPVPSHSHYYHALPYLKNLASLGHEITSVSPFP-SEEPV--------KNIYDIYVP------EVLNSFDELLK-QMTTPKN--TWEFFDATNEFVYNITKDVFNNDGVRREILRPGKA-QFDLIIVDIWKYDAFYSLAAYFEAPIIGLAPCGIDWKIDEMVGNPSPMSYLQSPSSYLYN---LDTFGGRVAHVVEVAISWFNWHWRYEQKHEALYKKYFPK---------------------------------------IAETKP--LSEISQDIALVLVNQHFTLG-PPRPYVPNVIEVGGMHIDEQP--KALAQDLEDFIQGSGEHGVIYFSLGTNVRTKNMVDDRKRILIEAFGSLPQ---RVLWKFEDEELQD-IPSNVLVRKWLPQQDLLAHPKVKLFITHGGMQSTIESIHYGKPMLGLPFFYDQFTNVDHIKKHGFCLSLN-YHDMTSDELKATILQLLTEKRFEVTARIAGARYRDQPMKPLETAVWWTHYVLRHK--GAPHMRVAGRKLSFFTHHSLDVLGTVLLVILLVIIAILLIIV-FSVCKISKNISTRLVVKKQR-KQKVR------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT1-1", "uniprot_id": "Q9VGT1_DROME", "id": "Q9VGT1-1", "name": "", "aln": "--------MPMSMLVLRLIVLVVALLPVLLEGARILGVFPIPSHSHYYHALPYLKKLASLGHEITSVSPFP-LKEPV--------ANIHDIPVP------ELFDNIEEIVG-NLTNRKG--TWNEFEYINQYTLGLVEKVLENDGVRREILQPESL-QFDLIIVDLWRLDALYGLAAYFDAPIIGIASYGTDWKIDELVGNVSPLAYLQSPSFNWFD---LDTYGGRLGHFVDQSMAWINWHWRHEERHEAVYRKYFPK---------------------------------------IADKRS--LSEITRNFALILVNQHFTMA-PPRPYVPNIIEVGGMHVDQQP--KALPQDLEDFIQGAGEHGVIYFSLGTNVRSRNLSKDRRKILIDTFASLPQ---RILWKFDADELSD-VPSNVLISPWFPQQDILAHPNVKLFITHGGLQSTVECIHRGVPMLGLPFFYDQFRNMEHIKAQGIGLVLN-YRDMTSDEFKDTIHQLLTEKSFGVKAKRTADRYRDQPMNPLDTAIWWTHYVLRHK--GAPHMRVAGRNLDFITYHSLDVLG----TFLLAVWAILSIVV-LCAIKLLRAILKSKKGNISP-KQKIN------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9X9-1", "uniprot_id": "Q9V9X9_DROME", "id": "Q9V9X9-1", "name": "UDP-glucuronosyltransferase", "aln": "---------------MPPIFLLVCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSPYP-QREPF--------RNIHDIPVP------EVFENFNEVLR-IASTPRS--TWQSSDFINEYVLNLTKTVLNNEGVRRDILGPQKP-HFDLVIMDLWRMDVLSGLAAYFDAPIIGMASYGTDWKIDELMGNVSPISYLQSPSSRFYD---LEAYGERLLHLMERTFSYMNYKWRHVRKQETLYSQFFPS---------------------------------------VAERKP--LSEISRNFDLVLVNQHFTLG-PPRPYVPNMIQVGGLHVDHST--EALSAELDHFIQGAGESGVIYFSLGTNVKSKSLSEDRRKVLLETFASLPQ---RIVWKFEDELLPG-KPPNVFISKWFPQQAILAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLN-IKQMTSEEFRSTIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHK--GAAHMQVAGKDLGFVRYHSLDVFG----TFLVGALVILGIVTYLLVMTLRKCLFLIKRGKCEA-IKKIQ------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT0-1", "uniprot_id": "Q9VGT0_DROME", "id": "Q9VGT0-1", "name": "UDP-glucuronosyltransferase", "aln": "------------MLALRIGFLLLT-LPASMQAARILAIFPFPGPSQYINVVPYLKELANRGHQVTSVNAFP-QKKPV--------VNFRDVFIP------DVFNNYKELIN-ELSGPMN--LWQENNFINKFFVSVTRCVLTNKEVTETLLPPGKD-HFDLIIVEALRSDAYYGFAAHFNAPIIGISTFGTDWNIDALVGNESPLSYTPLATGGLTD---RMTFLERLSNFVDTTVAWLNYRFVHMSEQEKMYAKYFPE---------------------------------------ASKRVQ--LTDLNRNFSLVLLNQHFSLS-FPRPYVPNMIEVGGLHISHKP--APLPKDLEEFIQGSGEHGVIYFSLGSNVLSKDLPADRKDLILKTFASLPQ---RVLWKFEDDKLPG-KPSNVFISKWFPQPDILAHPKVKLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLD-HTTMTQQELKETIEILLKEPRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHK--GAYHMRVAGQDLGFFAYHSLDVIG----VLLGGALLLVAIIV-----GVLGKLTDFGNAKKKL-KSK--------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGS9-1", "uniprot_id": "Q9VGS9_DROME", "id": "Q9VGS9-1", "name": "", "aln": "-MGGIFSVTGLGILLIGLIWLFAANADEGVQSSRILAVFPFPGRSQYIFAEQFMKELAHRGHNVTVINTFG-SDKNE--------PNFRVIGAK------KIHEIMAAFGNADYTQTAS--QWQMLTMTTQFLNLLTTSILDDAAVK-DLLNSGE--KFDLVIMEAVQTEALFGLIQHFGAETIGISSYGTDTHIDELMGNISPLSYNPLLLSSRTE---QMDFKDRVMNVFEASVMWLHKRIVHLPSQRDLYAKYFP-----------------------------------------TARKS--LDEVLDSFALMLLGQHFSLS-YPRPYLPNMIEVGGLHLQQKRKVQPLAKELSEFVEQS-EKGVIYFSMGSNIKSKDLPPSTRKMLMQTFASVPQ---RVLWKFEDDQLPE-KPDNVFISKWFPQPDILAHPNVKLFITHGGLLSTIESIYFGKPILGLPIFYDQHLNVQRAKQVGYGLSAD-IWSVNATELTPLIQELLSNPSYAAAAQTKSKLFRDQKETALERAIWWTEYVLRHK--GAKHLRCASRDLDFIQFHGLDTWG-LLIAITFVSLLIVVILIKCLQRVFVSLISKIRKNRAEASKLKTQ------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCL4-1", "uniprot_id": "Q9VCL4_DROME", "id": "Q9VCL4-1", "name": "", "aln": "-------MRLRYCWLTLSLCLLLQH--DRAQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLITPIG-MPNDI--------EGVRHIRVA------QLNERIKEMLESDQVLDFMINKWTESALTAKALFNASNDILSDPGVQ-RMLHDKSE-SFDLIIMEPSSLDALYGLVEFYNATLMGLSSIRINWHTYELAGNPAPSIYEPISPVGFSL---ETSLFSRVYNWIHIMEEKLVNYLILRPAQLHLFQKFFG-----------------------------------------YSAQK--MNELRSRFSLMLINSHYSMG-KVRANAPNIIEVGGLHLSEPP--EPSDEELQKFLDKA-DHGVIYFSMGNDILIKFLPENIQELLLQTFATLNE---SIIWKSELLYMPD-KSDNVYVVEQAPQRHILNHPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEVMD-INSLNKDTLTETIKHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNR--NITRMRLNLEEIPLIEYYRIDSILAFSLRFGLVAASLIFLVYTLF-LKYRIRLRRLHP-----------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCL3-1", "uniprot_id": "Q9VCL3_DROME", "id": "Q9VCL3-1", "name": "", "aln": "-------MRLGYAWLAFGLLLHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTPAD-YPAKI--------DGVRHIRVP------MLNQLMQNLMKNDQFFDALGDKWREGVLVSTIFYNVSHAILNNNGVQ-MLMRDKSI-RFDMIMVEASHLDALYGLAEFYNATLLGISCMHMTWHIDYLAGNLAPSVYEPISPNGFAL---DNTFLSRWSNWIYITEEKLLERLVFRPAQVRLFKKFFG-----------------------------------------YPAEK--LDELRARFSVILVNSHFSMG-RVRANVPNIIEVAGVHLSEPP--EPCGAELQKYLDEA-EHGAIYFSMGQDILIKYLPENMQKQLLLVFLQMKQ---RVIWKSELSMLAN-KSENIYVMDKVPQRMVLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLD-PNDLNADTLIETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNR--DTSHMRLNVEEIPLMRYYRLDSILTFGVRLGCVCGSLIFLGWRLY-QKNRNRHTRLQERERVIAQIQLGLSNYEVVS----------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGS7-1", "uniprot_id": "Q9VGS7_DROME", "id": "Q9VGS7-1", "name": "UDP-glucuronosyltransferase", "aln": "-----MFSGPGIAGLLLTVLLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLISAVT-IMPHI--------EGVHHIRVP------KLDMLMKILL--DFEYDTDLTKWTEAQFLSEYFYNCSKFVLEDPGVQ-ELLRNASA-KYSLIILEASHNDALYGFSQHFNAPLLGVAAYGSSWNIDFLVGNSAPSVYEPMSALGYTS---GLNLIEKWHNLIYITEERLVERFIYLPRQIDLYKQHFP-----------------------------------------GATTS--IHDLRRRFSLVLINQHFTMG-RVRSNVPNIVEVAGMHLDEKP--YPLDAELKKILDEA-EHGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQ---QVIWKTDYPEMVN-QSRNVFARTWFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLD-FKNLFRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHK--GADHMRIAEQEMSLMQYYNVDVVSVLFGRIGLSAIIVIFLGWKLVSLATRHLEYRLNVPMVR-------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGS8-1", "uniprot_id": "Q9VGS8_DROME", "id": "Q9VGS8-1", "name": "", "aln": "--------MFPPGRWLLPMFWLISNSICWIRSSRILVIAPFESHSQCMLVTPYIQALKDRGHQLTVIHAYKHCMHKI--------EDVTFIRIW------YNNNVFLEFEESVGIASAN-NKWEEISSMSSLMANATLNVLNNVEVR-ALMKSR-I-TFDAVVLEAGYSDVLYGMAAHFSAQLIGICTCVADWNINNLVGFSTSTLTEPIMPFRAKY---VKNVWDRIYNWLYTTEEWLLINLVFLPKQRLIHDHFFG-----------------------------------------HLEKS--FHEIRQDFALMLLNQHFSLF-RARPNVPGMVEVAGLHIPKED--PQLPSDLQVFIDEA-EHGVILFSLGLEQDSKDLPRKTQEILVETFKSVPQ---RVIWKFDGESTMS-LGTDIYHSKLLPQQAILAHPNVKLFISHCGMMSVIEAAYYAKPVLGLPSFFDQFRNLEIMKEEGVALELN-INSLTVKELKDAIHSMINEPEYRESALAISQRFRDQPIHPLDAAIYWTEYIIRYK--GADHMKISQSQLKLFDYYSLDNFIMVGSRLSLVVALVFLVLSKSRRWLNHLSTSAKSFLPTKHLIRS--------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG30-1", "uniprot_id": "Q9VG30_DROME", "id": "Q9VG30-1", "name": "", "aln": "--------MVHKSGIYLLLATAI-CVLGGCHGANILGVFTSLSPSHLIIQMSTAKVLAERGHNVTVITVLK-PVV-N-------HKNITVIMVPLT---KEESQQMSDTIGAMSKTDNSNMILSMLRMMGQMEFMFDKMAGALKDDRVRDLYLNRDNKFDLVLSGYFMNVYQLGFAKKVKAPVIVVATMPPNQLLNPLIGNPLEIAYVPSISDSVEK-GKGMSFRQRLAGYSSSFFFGIFDFVTQRRSKRLYKELFGD------------------------------------------DPNMPEYSELVKNTSLIFFASHAPSEGPIRPNVPAAIEIGGIQVKDTP--DPLPQNMAEFLGNA-TDGAILLSLGSNVKGSHINPDTVVKMFNVLSKLKQ---RVIWKWEDLEKTPGKSDNIFYSKWLPQDDILAHPNIKLFINHAGKGGITEAQYHGKPMLSLPVFGDQPGNADVMVKQGFGLTQS-LLSLEEQPFKEAILEILSNPQYFDKVASFSSLYRDRPMSARESVIYWTEYVIRHH--GAAHLQSPLVHMSFIAANNIDIYALIAVVLVILVLLLKLLLQFIYRKIFAKPKKEKKH-----------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VG29-1", "uniprot_id": "Q9VG29_DROME", "id": "Q9VG29-1", "name": "", "aln": "--------MVLRVEKFLLLAIAIGAVMGSSQGANILGLFPSLSPSHLIIQMSAAKVLAENGHNVTVVTVLK-PVV-N-------HKNITVIQVPLS---KEEAQQMSDTIGAMSKNDNSNMALSLLRMSDQMDFMIRKNAETLMNDRVRDLYLNRGNKFDLVISGYFMNDFQLGFARKVNAPVIVLATMPPNHLLNPLIGNPLEVSYAG-ISNPAEG-SKAVTFQRRLSSYMQSLGFGVFSHLSERRNRNWYKEVYGN------------------------------------------DPKMPEYSEMLKNTSLVFFSSHAASEGPIRPNVPSAIEIGGIQIKDKP--DPLPQNIAEFLGNA-TDGAILLSLGSNVQGKHLNPDTVAKMFNVLSKLKE---RVIWKWEDQENTPGKSANILYSKWLPQDDILAHPNIKLFINHAGKGGITESQYHGKPMLSLPVFADQPRNANAMVKSGFGLTLS-LLTLEEKPFQEAILEILSNPQYAERVKSFSTLYRDRPMTARESFLYWTEYVIRHH--GAAHLQSPLVHMSFIAANNIDICFLIFVILVSVLVLIKFLVQFIYRRFISKPKKEKTH-----------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VIM9-1", "uniprot_id": "Q9VIM9_DROME", "id": "Q9VIM9-1", "name": "", "aln": "--------MVGRTKSYFVIVLALTLLIYGAQGANILGLFPSLSPSHLIISMSVAKILAEQGHNVTVVTVLE-PTI-T-------HKNINLVTVPMT---KEEIKQRSETIGAKQKNTSSNRFISILNMSGQMDSMLRKMADVLKDQRVKELYLNKDNHFDLVISGYFMNDYQLGFARKVNAPVVVLAPSPPSQMLNSLIGNP---------HDKVEK-EKGMTFGQRLDSYISSLLYGIFLRQIDQRNRQYYNEIFGD------------------------------------------DPTMPEYTDILRNTSLVFFCSHAASEGPIRPSVPAAIEIGGIQIKDKP--DPLPKNLEKFLGNA-THGAILLSLGSNVQGSHIKADTVKKIFSVLSNLKQ---RVIWKWDDLDKTPGKSDNILYSRWLPQDDILAHPSVKLFINHAGKGGISEAQYHGKPMLSLPVFGDQPGNAHAMVKSGFGLTLS-LLTLEEEPFRAAVLEILSNPKYSQRVVKFSSLYRDRPASARESLIFWTEYVIRHH--GAAHLQSPLVHMDFIAANNLDIYALIGAISIGLLLMLKKVVQITCRRLRTKLNKVKKQ-----------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMG1-1", "uniprot_id": "Q9VMG1_DROME", "id": "Q9VMG1-1", "name": "", "aln": "-----------MGGISRCLALQIVVLIAGAHGANILGLFTSLSPSHLVIQMSMARILAERGHNVTVVTILK-PPS-L-------HKDINHILVPME---EDILQAFNSVVGGMTKTDNSNAYVSMFRSVRQLSETFSKMGDVMKQPLVKDLYEHPDNKFDLVMVGYFMNCYQLALAHKLKVPLVVALSNPPS-FLGYLLGNPWEVSYVPGMSVSIKG-GKPLGFGHRVLNLLGSMAQRLFMFIIELRNARIYREIYGD------------------------------------------DPTLPSYEDLHKNISLIFFASHGISEGPIRPNVPAVIEIGGIQVKEQP--ERLPQNMEQFLSEA-PNGAILLSLGSNLKEDHLKSSTVQKMFNVLSKLQQ---KVIWKWDDLDNIPGESENILYSKWVPQVDVLAHPNITLFITHAGKGGLTEAQYHGKPMLALPVFGDQPSNADVMVMHGFGIKQS-ILTLEEDSFLQGIREVLDNPKYATAVKSFSTLYRDRPLSPRETLIYWVEYVIRYH--GAPHIQSPVVHMSYIAANNLDVYAVILGTIVALCFITKLLFGLVVGKLRKNSRKAKVNQKHKLKKKQS-------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJI0-1", "uniprot_id": "Q9VJI0_DROME", "id": "Q9VJI0-1", "name": "", "aln": "-----------MIGVHFVFLLLLGVVAS-TQGANILGLFSSHSPSHLIIHMSVAKALVKAGHNVTVVSMLK-PKV-T-------HKDIHLIVVPMK---EEQERIMEDQMTEMAGQKNS-LVSTMYRLLTSMDVMINAQAELLSDPRFQRIYET---KFDLMILGYFINDFQLGVAHKLKVPVIINWMSAPVPAIDKYTGNPSELSYVPLMGTVAT---QPMGFLKRTENALKSLLFEFIFVVFDYKLTRIYNDVFP-------------------------------------------EQDMPTLKELRKNISMAFVGSHLISEGPIRPLVPALIEIGGIQVKDKP--DPLPKDIDQFISNA-KQGAVFLSLGSNVKSSTVRPEIVQIIFKVLSELKE---NVIWKWEDLENTPGNSSNILYKNWLPQDDILAHPNTKLFITHAGKGGITEAQYHGVPMVALPIFGDQPGNAALMEKSGYGLALD-LLSITEDSLRDALKEVLENQKYKQAIGQFSTLYRDRPMTAKQSVVFWTEYILRHQ--GAPNLQSPSVHMNFIQLNNLDIYALIVTILVLFVLLTRLVAKIVWNKFGGKA-KISQTK--KKQ-----------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJH8-1", "uniprot_id": "Q9VJH8_DROME", "id": "Q9VJH8-1", "name": "", "aln": "MTQNRSTWIGCSLGGLLVALLALQTMPQGTEGANILGVFTSHSPSHFIVHMSIMKTLAEKGHNVTVVSSVP-PKV-T-------HKSINHIVVPMS---AEDEKVLNDGMAGMVKEKPS-IWNTMKSIFSSLALLIDKQVDVLEDPRFQELYLNKGNKFDVVFVGFFFNTYQVALGARFNCPVIISWSGPPMMMVNEVLGNP-ELSSVPQMHISAPP-GQPMNFQQRMQNFASTLGFNALNIFLNHKYNKFYDRLWSK------------------------------------------DKSMPTFAQAKRNVSLAFCNGHGISEGPIRPNVPGVIEIGGIQVKSKP--DPLPEDIQEFLEKG-KHGAILFSLGSNLKGEHIQPEVVKTIFKGLSSLKQ---QVIWKWEDPKNTPGKSANILYKKWLPQDDILAHPKLKLFITHAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVASGYGLQLP-LATLDVDEFKAAIKEVIENPKYAKTLKSFSQLYRDRPLSPQESVVYWTEYVIRHH--GAAHMQSPLVHMNFIASNNLDIYIIAALVLYIVFIINKIVWKFVWRKLFGKSNKVSKGKKVKKQ-----------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJH9-1", "uniprot_id": "Q9VJH9_DROME", "id": "Q9VJH9-1", "name": "", "aln": "--------MIEYTKIGFLIAFLLSTMTQSSGGANILGVFGTHSPSHVIVHMAVMKALADRGHNITVVTQMK-PKLAT-------HENITVIIAPPT---EERQRYIKEYMAEVSNEKPS-FWETMVKAIVQSSNQLEGQYEFMTHPNVKEIYENPKIKFDLVFLGLMANTYQLGIAAKLKCPVIISWVGIPLPFMDTIVGNVNDPSYVPTVNVALNAGQKTMDFGLRFVNFFKYAIMCVFETVLDYKMNQFYERAFAN------------------------------------------ELEFPNYHEMKRRVSLLFYNYHSASEGPIRPTVPQSIEIGGIQVKEQA--DPLPKELAKFLDKA-DEGAIFFSLGTNVNTNTFRPDTVDILYKVLSKLPQ---RVIWKWEDLKNKPGNASNIFFGNWLPQDDILAHPNTKLFITHAGKGGVAEAQYHGVPMVALPIFGDQQGNAEIMTKSGFGRWLD-ILTMTEHELEQTIREVLGNPAYRETIGKFSTLYRDRPLTARQSVIYWTEYVLRHQ--GALHLQSPLIHTKFVARNNLDVYGVVLLVSLLLIVTIKFLFRKILNVAIGYGSQRKAVANKLKNN----------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36510-1", "uniprot_id": "UD2A1_RAT", "id": "P36510-1", "name": "UDP-glucuronosyltransferase 2A1", "aln": "--------------MLKNILLWSLQLSLLGMSLGGNVLIWPMEGSHWLNVKIIIDELLRKEHNVTVLVASGALFITP-SVSPSLTFEIYPVPFGKEKIESVIKDFVLTWLENRPSPSTIWTFYKEMAKVIEEFHLVSRGICDGVLKNEKLMTKLQRGKFEVLLSDPVFPCGDIVALKLGIPFIYSLRFSPASTVEKHCGKVPFPPSYVPAILSELTD---QMSFADRVRNFISYRMQDYMFETL-WKQWDSYYSKALG--------------------------------------------RPTTLCETMGKAEIWLMRTYWDFE-FPRPYLPNFEFVGGLHCKPAK---PLPKEMEEFVQTSGEHGVVVFSLGSMV--KNLTEEKANLIASALAQIPQ---KVLWRYKG-KIPATLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVN-MNTMTSADLLSAVRAVINEPFYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHK--GAKHLRVAAHDLSWFQYHSLDVIGFLLACMASAILLVIKCCLFVFQKIGK--TXKKNKRD---------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80X89-1", "uniprot_id": "UD2A1_MOUSE", "id": "Q80X89-1", "name": "UDP-glucuronosyltransferase 2A1", "aln": "--------------MLKNILLCSLQISLLGMSLGGNVLIWPMEGSHWLNVKIIIDELLRKEHNVTVLVASGALFITPSSISPSLTFEIYPVPFGKEKIESVIKDFVLTWLENRPSPSTIWTFYKEMAKVIEEFHLVSRGICDGVLKNEKLMSKLQKEKFEVLLSDPVFPCGDIVALKLGIPFIYSLRFSPASTVEKHCGKVPFPPSYVPAILSELTD---QMSFTDRVRNFISYRMQDYMFETL-WKQWDSYYTKALG--------------------------------------------RPTTLCETMGKAEIWLMRTYWDFE-FPRPYLPNFEFVGGLHCKPAK---PLPKEMEEFVQTSGEHGIVVFSLGSMV--KNLTDEKANLIASALAQIPQ---KVLWRYKG-KIPDTLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVN-MNTMTSSDLLNALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHK--GAKHLRVAAHDLSWFQYHSLDVIGFLLACVASAILLVAKCCLFIFQKVGK--TGKKKKRD---------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DTE4-5", "uniprot_id": "UD2A1_HUMAN", "id": "P0DTE4-5", "name": "UDP-glucuronosyltransferase 2A1", "aln": "--------------MLNNLLLFSLQISLIGTTLGGNVLIWPMEGSHWLNVKIIIDELIKKEHNVTVLVASGALFITP-TSNPSLTFEIYKVPFGKERIEGVIKDFVLTWLENRPSPSTIWRFYQEMAKVIKDFHMVSQEICDGVLKNQQLMAKLKKSKFEVLVSDPVFPCGDIVALKLGIPFMYSLRFSPASTVEKHCGKVPYPPSYVPAVLSELTD---QMSFTDRIRNFISYHLQDYMFETL-WKSWDSYYSKALGGLLLCCPGWSAVADLGSLQPLLPGFKRFSRLSLHCSWDYRLPAGRPTTLCETMGKAEIWLIRTYWDFE-FPRPYLPNFEFVGGLHCKPAK---PLP-------------------------------------------------KVLWRYKG-KKPATLGNNTQLFDWIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPMVGVPMFADQPDNIAHMKAKGAAVEVN-LNTMTSVDLLSALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHK--GAKHLRVAAHDLTWFQYHSLDVIGFLLVCVTTAIFLVIQCCLFSCQKFGK--IGKKKKRE---------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DTE5-1", "uniprot_id": "UD2A2_HUMAN", "id": "P0DTE5-1", "name": "UDP-glucuronosyltransferase 2A2", "aln": "-----MVSIRDFTMPKKFVQMLVFNLTLTEVVLSGNVLIWPTDGSHWLNIKIILEELIQRNHNVTVLASSATLFINS-NPDSPVNFEVIPVSYKKSNIDSLIEHMIMLWIDHRPTPLTIWAFYKELGKLLDTFFQINIQLCDGVLKNPKLMARLQKGGFDVLVADPVTICGDLVALKLGIPFMYTLRFSPASTVERHCGKIPAPVSYVPAALSELTD---QMTFGERIKNTISYSLQDYIFQSY-WGEWNSYYSKILG--------------------------------------------RPTTLCETMGKAEIWLIRTYWDFE-FPRPYLPNFEFVGGLHCKPAK---PLPKEMEEFIQSSGKNGVVVFSLGSMV--KNLTEEKANLIASALAQIPQ---KVLWRYKG-KKPATLGNNTQLFDWIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPMVGVPMFADQPDNIAHMKAKGAAVEVN-LNTMTSVDLLSALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHK--GAKHLRVAAHDLTWFQYHSLDVIGFLLVCVTTAIFLVIQCCLFSCQKFGK--IGKKKKRE---------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PDD0-1", "uniprot_id": "UD2A2_MOUSE", "id": "Q6PDD0-1", "name": "UDP-glucuronosyltransferase 2A2", "aln": "-------------MIKKVLQLLIFHLTLAEIVLSGNVVVWPTDGSHWLNIKILLEELVQRNHSVTVLAPSETLFINS-RLDAFINFEEIPVSYTKSKIDEIIEHMIALWLDHRPTPLTMWTFYKELGNLLATFYTTNKQMCDGVLNNPTVMERLQKGGFDVLLADPVTMCGELVALKLGIPFVYTLRFSPAFTVERHCGKIPAPISYVPAALSELTD---QMSFGERVKNIISYSLQDYIFKTY-WGEWNSYYSKVLG--------------------------------------------RPTTLCETMGKAEIWLMRTYWDFE-FPRPYLPNFEFVGGLHCKPAK---PLPKEMEEFVQTSGEHGIVVFSLGSMV--KNLTDEKANLIASALAQIPQ---KVLWRYKG-KIPDTLGSNTRLFDWIPQNDLLGHPKTRAFITHGGTNGIYEAIYHGIPMVGVPMFADQPDNIAHMKAKGAAVEVN-MNTMTSSDLLNALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHK--GAKHLRVAAHDLSWFQYHSLDVIGFLLACVASAILLVAKCCLFIFQKVGK--TGKKKKRD---------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8BWQ1-1", "uniprot_id": "UD2A3_MOUSE", "id": "Q8BWQ1-1", "name": "UDP-glucuronosyltransferase 2A3", "aln": "-----------MVSEKCVAAFFLLQLCWAGCGFCSKVLVWPCDMSHWLNLKTILEELGARGHEVTVLKYP-SIIIDQ-SKRIPLHFENIPLLYEIETAENRLNEIANLAVNVIPN-LSLWEAAKTLQDFFLQVTGDFESICRSVLYNQKFMDKLRDAQYDVVVIDPVVPCGELVAEVLQIPFVYTLRFSMGYYMEKHCGQLPIPLSYVPVVMSELTD---NMTFTERVKNMMFSLLFEYWLQQYDFAFWDQFYSETLG--------------------------------------------RPTTFCKTVGKADIWLIRTYWDVE-FPRPYLPNFEFVGGLHCKPAK---PLPKEMEEFVQSSGEHGVVVFSLGSMV--KNLTEEKANLIASVLAQIPQ---KVLWRYSG-KKPATLGSNTRLFNWIPQNDLLGHPKTKAFITHGGTNGIYEAIYHGVPMVGVPMLGDQPHNIAHMEAKGAALKVS-ISTMTSTDLLSAVRAVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHK--GAKHLRVAAHDLSWFQYHSLDVIGFLLLCVVTLTFIITKFCLFVCQKLYMKESKKMGNRKKKN------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UWM9-1", "uniprot_id": "UD2A3_HUMAN", "id": "Q6UWM9-1", "name": "UDP-glucuronosyltransferase 2A3", "aln": "-----------MRSDKSALVFLLLQLFCVGCGFCGKVLVWPCDMSHWLNVKVILEELIVRGHEVTVLTHSKPSLIDY-RKPSALKFEVVHMPQD-RTEEN--EIFVDLALNVLPG-LSTWQSVIKLNDFFVEIRGTLKMMCESFIYNQTLMKKLQETNYDVMLIDPVIPCGDLMAELLAVPFVLTLRISVGGNMERSCGKLPAPLSYVPVPMTGLTD---RMTFLERVKNSMLSVLFHFWIQDYDYHFWEEFYSKALG--------------------------------------------RPTTLCETVGKAEIWLIRTYWDFE-FPQPYQPNFEFVGGLHCKPAK---ALPKEMENFVQSSGEDGIVVFSLGSLF--QNVTEEKANIIASALAQIPQ---KVLWRYKG-KKPSTLGANTRLYDWIPQNDLLGHPKTKAFITHGGMNGIYEAIYHGVPMVGVPIFGDQLDNIAHMKAKGAAVEIN-FKTMTSEDLLRALRTVITDSSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHK--GAKHLRSAAHDLTWFQHYSIDVIGFLLACVATAIFLFTKCFLFSCQKFNK--TRKIEKRE---------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O75310-1", "uniprot_id": "UDB11_HUMAN", "id": "O75310-1", "name": "UDP-glucuronosyltransferase 2B11", "aln": "-----------MTLKWTSVLLLIHLSCYFSSGSCGKVLVWAAEYSHWMNMKTILKELVQRGHEVTVLASSASILFDP-NDASTLKFEVYPTSLTKTEFENIIMQQVKRWS--DIRKDSFWLYFSQEQEILWELYDIFRNFCKDVVSNKKVMKKLQESRFDIVFADAVFPCGELLAALLNIRFVYSLRFTPGYTIERHSGGLIFPPSYIPIVMSKLSD---QMTFMERVKNMIYVLYFDFWFQMSDMKKWDQFYSEVLG--------------------------------------------RPTTLFETMGKADIWLMRNSWSFQ-FPHPFLPNVDFVGGFHCKPAK---PLPKEMEEFVQSSGENGVVVFSLGSVI--SNMTAERANVIATALAKIPQ---KVLWRFDG-NKPDALGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMKAKGAAVRLD-FNTMSSTDLLNALKTVINDPLYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMPHK--GAKHLRVAAHDLTWFQYHSLDVIGFLLACVATVIFIITKFCLFCFWKFAR--KGKKGKRD---------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BY64-1", "uniprot_id": "UDB28_HUMAN", "id": "Q9BY64-1", "name": "UDP-glucuronosyltransferase 2B28", "aln": "-----------MALKWTSVLLLIHLGCYFSSGSCGKVLVWTGEYSHWMNMKTILKELVQRGHEVTVLASSASILFDP-NDAFTLKLEVYPTSLTKTEFENIIMQQVKRWS--DIQKDSFWLYFSQEQEILWEFHDIFRNFCKDVVSNKKVMKKLQESRFDIIFADAFFPCGELLAALLNIPFVYSLCFTPGYTIERHSGGLIFPPSYIPVVMSKLSD---QMTFMERVKNMIYVLYFDFWFQMCDMKKWDQFYSEVLG--------------------------------------------RPTTLFETMGKADIWLMRNSWSFQ-FPHPFLPNIDFVGGLHCKPAK---PLPKEMEEFVQSSGENGVVVFSLGSVI--SNMTAERANVIATALAKIPQ---KVLWRFDG-NKPDALGLNTRLYKWIPQNDLLGLPKTRAFITHGGANGIYEAIYHGIPMVGIPLFWDQPDNIAHMKAKGAAVRLD-FHTMSSTDLLNALKTVINDPSYKENVMKLSIIQHDQPVKPLHRAVFWIEFVMCHK--GAKHLRVAARDLTWFQYHSLDVIGFLLACVATVIFVVTKFCLFCFWKFAR--KGKKGKRD---------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36537-1", "uniprot_id": "UDB10_HUMAN", "id": "P36537-1", "name": "UDP-glucuronosyltransferase 2B10", "aln": "-----------MALKWT-TVLLIQLSFYFSSGSCGKVLVWAAEYSLWMNMKTILKELVQRGHEVTVLASSASILFDP-NDSSTLKLEVYPTSLTKTEFENIIMQLVKRLS--EIQKDTFWLPFSQEQEILWAINDIIRNFCKDVVSNKKLMKKLQESRFDIVFADAYLPCGELLAELFNIPFVYSHSFSPGYSFERHSGGFIFPPSYVPVVMSKLSD---QMTFMERVKNMLYVLYFDFWFQIFNMKKWDQFYSEVLG--------------------------------------------RPTTLSETMRKADIWLMRNSWNFK-FPHPFLPNVDFVGGLHCKPAK---PLPKEMEEFVQSSGENGVVVFSLGSMV--SNMTEERANVIATALAKIPQ---KVLWRFDG-NKPDALGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFFDQPDNIAHMKAKGAAVRVD-FNTMSSTDLLNALKTVINDPSYKENIMKLSRIQHDQPVKPLDRAVFWIEFVMRHK--GAKHLRVAAHNLTWFQYHSLDVIGFLLACVATVLFIITKCCLFCFWKFAR--KGKKGKRD---------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P16662-1", "uniprot_id": "UD2B7_HUMAN", "id": "P16662-1", "name": "UDP-glucuronosyltransferase 2B7", "aln": "-----------MSVKWTSVILLIQLSFCFSSGNCGKVLVWAAEYSHWMNIKTILDELIQRGHEVTVLASSASILFDP-NNSSALKIEIYPTSLTKTELENFIMQQIKRWS--DLPKDTFWLYFSQVQEIMSIFGDITRKFCKDVVSNKKFMKKVQESRFDVIFADAIFPCSELLAELFNIPFVYSLSFSPGYTFEKHSGGFIFPPSYVPVVMSELTD---QMTFMERVKNMIYVLYFDFWFEIFDMKKWDQFYSEVLG--------------------------------------------RPTTLSETMGKADVWLIRNSWNFQ-FPYPLLPNVDFVGGLHCKPAK---PLPKEMEDFVQSSGENGVVVFSLGSMV--SNMTEERANVIASALAQIPQ---KVLWRFDG-NKPDTLGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGIPLFADQPDNIAHMKARGAAVRVD-FNTMSSTDLLNALKRVINDPSYKENVMKLSRIQHDQPVKPLDRAVFWIEFVMRHK--GAKHLRVAAHDLTWFQYHSLDVIGFLLVCVATVIFIVTKCCLFCFWKFAR--KAKKGKND---------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06133-1", "uniprot_id": "UD2B4_HUMAN", "id": "P06133-1", "name": "UDP-glucuronosyltransferase 2B4", "aln": "-----------MSMKWTSALLLIQLSCYFSSGSCGKVLVWPTEFSHWMNIKTILDELVQRGHEVTVLASSASISFDP-NSPSTLKFEVYPVSLTKTEFEDIIKQLVKRWA--ELPKDTFWSYFSQVQEIMWTFNDILRKFCKDIVSNKKLMKKLQESRFDVVLADAVFPFGELLAELLKIPFVYSLRFSPGYAIEKHSGGLLFPPSYVPVVMSELSD---QMTFIERVKNMIYVLYFEFWFQIFDMKKWDQFYSEVLG--------------------------------------------RPTTLSETMAKADIWLIRNYWDFQ-FPHPLLPNVEFVGGLHCKPAK---PLPKEMEEFVQSSGENGVVVFSLGSMV--SNTSEERANVIASALAKIPQ---KVLWRFDG-NKPDTLGLNTRLYKWIPQNDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGVPLFADQPDNIAHMKAKGAAVSLD-FHTMSSTDLLNALKTVINDPLYKENAMKLSRIHHDQPVKPLDRAVFWIEFVMRHK--GAKHLRVAAHDLTWFQYHSLDVTGFLLACVATVIFIITK-CLFCVWKFVR--TGKKGKRD---------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54855-1", "uniprot_id": "UDB15_HUMAN", "id": "P54855-1", "name": "UDP-glucuronosyltransferase 2B15", "aln": "-----------MSLKWTSVFLLIQLSCYFSSGSCGKVLVWPTEYSHWINMKTILEELVQRGHEVTVLTSSASTLVNA-SKSSAIKLEVYPTSLTKNYLEDSLLKILDRWIY-GVSKNTFWSYFSQLQELCWEYYDYSNKLCKDAVLNKKLMMKLQESKFDVILADALNPCGELLAELFNIPFLYSLRFSVGYTFEKNGGGFLFPPSYVPVVMSELSD---QMIFMERIKNMIHMLYFDFWFQIYDLKKWDQFYSEVLG--------------------------------------------RPTTLFETMGKAEMWLIRTYWDFE-FPRPFLPNVDFVGGLHCKPAK---PLPKEMEEFVQSSGENGIVVFSLGSMI--SNMSEESANMIASALAQIPQ---KVLWRFDG-KKPNTLGSNTRLYKWLPQNDLLGHPKTKAFITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVD-IRTMSSRDLLNALKSVINDPVYKENVMKLSRIHHDQPMKPLDRAVFWIEFVMRHK--GAKHLRVAAHNLTWIQYHSLDVIAFLLACVATVIFIITKFCLFCFRKLAK--KGKKKKRD---------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O75795-1", "uniprot_id": "UDB17_HUMAN", "id": "O75795-1", "name": "UDP-glucuronosyltransferase 2B17", "aln": "-----------MSLKWMSVFLLMQLSCYFSSGSCGKVLVWPTEYSHWINMKTILEELVQRGHEVIVLTSSASILVNA-SKSSAIKLEVYPTSLTKNDLEDFFMKMFDRWTY-SISKNTFWSYFSQLQELCWEYSDYNIKLCEDAVLNKKLMRKLQESKFDVLLADAVNPCGELLAELLNIPFLYSLRFSVGYTVEKNGGGFLFPPSYVPVVMSELSD---QMIFMERIKNMIYMLYFDFWFQAYDLKKWDQFYSEVLG--------------------------------------------RPTTLFETMGKAEMWLIRTYWDFE-FPRPFLPNVDFVGGLHCKPAK---PLPKEMEEFVQSSGENGIVVFSLGSMI--SNMSEESANMIASALAQIPQ---KVLWRFDG-KKPNTLGSNTRLYKWLPQNDLLGHPKTKAFITHGGTNGIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVD-IRTMSSRDLLNALKSVINDPIYKENIMKLSRIHHDQPVKPLDRAVFWIEFVMRHK--GAKHLRVAAHNLTWIQYHSLDVIAFLLACVATMIFMITKCCLFCFRKLAK--TGKKKKRD---------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB12ZY70-1", "uniprot_id": "A0AB12ZY70_DANRE", "id": "A0AB12ZY70-1", "name": "UDP-glucuronosyltransferase", "aln": "---------------MRPLACFLSLLSLLSAGECGNVLVWFTEGSHWINMKIVLETLIDRGHDVTVLVPDASLFMKA-NASDRFSYQPFNVSMDEQEMKVFIEEFLYFSLY-EMDQLNFFQMQSKVYEFTSKLQDMSISYCDGVLKSPGLLDKLRKHKFDVVFSDPIYQCSDIVAEELNVPLVYTFRFSLAHAAERMCGQIPAPPSYVPGAMSKLTD---KMSFTERIYNMLFYLSQD-AFAIFAWKKIDNYYTEYFG--------------------------------------------RPTSYCEMMGRADIWLIRTYWDFE-FPRPFVPNFKYIGGLHCTPAK---PLPKDMEEFVQSSGEDGIVVFTLGSLV--GKVPKEISNRIASALAQIPQ---KVLWRYGG-EKPDTLGENTRIYKWIPQNDLLGHPKTRAFITHGGTNGVYEAIYHGVPMVGIPLFGDQPDNMVHMTTRGAAVVVDSIKSMQPQELVDKLNTVINDPSYKENAMRLSRIHHDRPMKPLDESVFWIEFVMRNK--GAKHLRVEAHNLTWYQYHCLDVFAFLTTVLTLVLYICFKMAKFFIMRCCFR-SKRKSKKE---------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVW2-1", "uniprot_id": "Q9VVW2_DROME", "id": "Q9VVW2-1", "name": "", "aln": "--------------MQILQVFLGTLLCGIVLGANVLTVFPSVWKSHYLFGRRLLQELVESSGNHSVTLISPHAAQEG--------VDAEIPKIRELRIEGLRENWLDMGMSFEAEEMRAQSVMERFTRLIYAGTTNVDILLSDPQVRKLLTSGEK---FDLLIVDLFLSDALLGLAFYYGIPTVAVSPTGANSWLNNMFGNPQSSSLDPSNFLPFTE---RMNTRQRILNSLMSTFERLTYNFFHLISQQSVYTNHFEL----------------------------------------LVKELPLYRDLTKNLSLALINSHPGLH-YPRAYLPNMVEVGGLHLSHLN-DDNLPKHLLSFMESA-PSGVIYFSLGADVETAQLPQEKLAIILDVFGHLKEFHFLLKWEKEEFTAEQVLPENVMIADWWPQQAILHHPQVKMFISSCGQLSVWESISGQKPVLAIPILAEQEVMAKRLQRHGVSVTVG-YDSLAYDSLLHGIRQLTLNTSYVEKLGQLKERLISRDSTPVGKAVRKIQLILESG--GADFLKSHANTLNFWRAEGVDVLLIIAVGFFGILTIPFLAICFILRKSYHSQAAQDQPPYRTNLKVVGRVHSYGDQGSSRSPKGTESLRRTRSAQSLSARSSSSSMSSNSPTSPSTASTTPLDLTPPPPIQLLGQVPPLQLYVNQQRIYSSDRKTSQEEAERRFS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * :. :. : : :.* : : *. . ** :* * * . * *:: * :* : . : . : . . . : :* ", "identical_positions": 14, "similar_positions": 27, "identity": "1.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100405-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R560-1", "uniprot_id": "ANKR1_RAT", "id": "Q8R560-1", "name": "Ankyrin repeat domain-containing protein 1", "aln": "MMVFRVEELVTGKKNSNGSSGE-FLPGEFRNGEYEAAVALEKQEDLKTLPANSVNLGEEQRKSEKVREAELKKKKLEQRSKLENLEDLEIIVQLKKRKKYKKTKVPVVKEPEPEIITEPVDVPRFLKAALENKLPVVEKFLSDKNSPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWACRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLLMTFGADLNVKNCAGKTPMDLVLHWQNGTKAIFDSLKENAYKNSRIATF--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CR42-1", "uniprot_id": "ANKR1_MOUSE", "id": "Q9CR42-1", "name": "Ankyrin repeat domain-containing protein 1", "aln": "MMVLRVEELVTGKKNSNGAAGE-FLPGEFRNGEYEAAVALEKQEDLKTLPANSVKQGEEQRKSEKLREAELKKKKLEQRSKLENLEDLEIIVQLKKRKKYKKTKVPVVKEPEPEIMTEPVDVPRFLKAALENKLPVVEKFLSDKNSPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWACRGGNADVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLLMTFGADLKVKNCAGKTPMDLVLHWQSGTKAIFDSLKENAYKNSRIATF--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15327-1", "uniprot_id": "ANKR1_HUMAN", "id": "Q15327-1", "name": "Ankyrin repeat domain-containing protein 1", "aln": "MMVLKVEELVTGKKNGNGEAGE-FLPEDFRDGEYEAAVTLEKQEDLKTLLAHPVTLGEQQWKSEKQREAELKKKKLEQRSKLENLEDLEIIIQLKKRKKYRKTKVPVVKEPEPEIITEPVDVPTFLKAALENKLPVVEKFLSDKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDTPLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDLVLHWQNGTKAIFDSLRENSYKTSRIATF--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PP67-1", "uniprot_id": "A0A8M9PP67_DANRE", "id": "A0A8M9PP67-1", "name": "Ankyrin repeat domain-containing protein 1", "aln": "MGLLRVEELVTGKR-GEGRVGESACAEVFAAGEYETSIIQEKQDGIHTQQDLNDTTQNDTKPSELKPKLNVDR---SGHLKLETVEDLFNILELRKRRKERKIQM-LKKEPEPDILPETVDQGLFLKAVTENKLPVVEKYLVDGGDPNVCDHFKRSALHKASAQGHTEIMQKLLESGASMDQKDKLDATAVHWACRGGSLPALELLLNKGAKFNSRDKLSSTPLHVAVRTGHYECAEHLIHCGADVNAKDRDGDTPMHDAVRINRFKMIRLLMMYGASLNAKNNDGKTPMETLLSWQKGVKNILNNLNECEAPKSDEQLFSI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :::********: .:* ** . * ****::: ***:.::* . :: ** : ::.: . : ***.:*** *::*:**:* :* :: : *****:*:.*.** ****. *********:* * ..*:***.:**:***:*. :** *::**:*:**.:: :* *::**:***.***. .*:********:.:**** **.***************** * **:*****:****:*****:**:******: :**.*: ** *****: :* **.*.* *::.*.* .* * ", "identical_positions": 164, "similar_positions": 86, "identity": "50.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100405-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U5R9-1", "uniprot_id": "HECD2_HUMAN", "id": "Q5U5R9-1", "name": "Probable E3 ubiquitin-protein ligase HECTD2", "aln": "MSEAVRVPSPATPLVVAAPAPEERKGKESEREKLPPIVSAGAGATAGLDRGAKGQISTFSSFISAVSPKKEAAENRSSPAHLVFPNIKNVREPPPICLDVRQKQRTSMDASSSEMKAPVLPEPILPIQPKTVKDFQEDVEKVKSSGDWKAVHDFYLTTFDSFPELNAAFKKDATASFNTIEDSGINAKFVNAVYDTLLNTPQDVQKTVLKGIINSLLREWKGPRTKDDLRAYFILLQNPQFNNTSTYVIYAHLLRQIATLVEADHHFLVHWFKKLSQKRFKQLVERLLQFISLRLFPAKPEEFPPITKCSWWIPSAAKVLALLNTANNLVHPPLIPYTDFYNSTLDHIDLMEEYHTWQNFGNSHRFSFCQYPFVISVAAKKIIIQRDSEQQMINIARQSLVDKVSRRQRPDMNILFLNMKVRRTHLVSDSLDELTRKRADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSHCHWFSSFKCDNYSEFRLVGILMGLAVYNSITLDIRFPPCCYKKLLSPPIIPSDQNIPVGICNVTVDDLCQIMPELAHGLSELLSHEGNVEEDFYSTFQVFQEEFGIIKSYNLKPGGDKISVTNQNRKEYVQLYTDFLLNKSIYKQFAAFYYGFHSVCASNALMLLRPEEVEILVCGSPDLDMHALQRSTQYDGYAKTDLTIKYFWDVVLGFPLDLQKKLLHFTTGSDRVPVGGMADLNFKISKNETSTNCLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGLE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CDU6-1", "uniprot_id": "HECD2_MOUSE", "id": "Q8CDU6-1", "name": "Probable E3 ubiquitin-protein ligase HECTD2", "aln": "MSEAARDLSPGAPPAVAAAAPEERKGKEPEREKLPPIVTAGA--AAGLDRGSKGQISTFSSFVSTVTQKKEAAENRSSPTHLALPNIRNVRDLPPICLDVRQKQRMSVEALPSEVKVPPLPEPSLPSQPKTVKDFEEDLEKAEATGNWKTVHAFYITAFDSFTELNTAFKKDATASFNTIEDSGLNANLVNAVFDALLNTPQDIQKSVLKGIINSLLQEWKGPRTKDDLRAYFILLQNPQFNITSTYVIYAHLLRQIATLVEADHHFLVHWLKKLSQKKFKQLVERLLQFVSLRLFPAKPEEFPPLTKCTWWIPSAAKVLALLNTANNLVHPPLVPYTDFYNSTLDHIDLMEEYHTWQSFGNSHRFSFCQYPFVISIAAKKIIIQRDSEQQMISIARQSLVDKVSRRQRPDMNMLFLNMKVRRTHLVSDSLDELTRKRADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHPDYGMFTYHKDSHCHWFSSFKCDNYSEFRLVGILMGLAVYNSITLDIRFPPCCYKKLLSPPVVPSDQSTPVGICSVTIDDLCQVMPELAHGLKELLSYEGNVEEDFYSTFQVFQEEFGVIKSYNLKPGGDKIPVTNQNRREYVQLYTDFLLNKSIYKQFAAFYCGFHSVCASNALMLLRPEEVEILVCGSPELDMHALQRSTQYDGYAKTDLTIRYFWDVVLGFPLELQKKLLHFTTGSDRVPVGGMADLNFKISKNETSTNWLPVAHTCFNQLCLPPYKSKKDLKQKLIIGISNSEGFGLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7EYX5-1", "uniprot_id": "E7EYX5_DANRE", "id": "E7EYX5-1", "name": "HECT-type E3 ubiquitin transferase", "aln": "MHLNMSENN----------CPLE----ERDRDRLPPIINHQN-----LERGPKLPFPSYGSFISTLNHKRESG-SHSFSSPLFLPAVKQVRELPPIYPDVRQKHRISIDVLPPEVKARFVSEPIIPIRTKTAKEFQDDVERATISGDWKHVHDFYLTTFDSFLELNGAFKKEANAPFNTIEDSGINIKFVNIVYDALLHTPADTQKSVLKGIINSLLREWKGPRTKDDLRAYFVLVQNPQYTSPATYVIYAHLLRQIAALAEADHHFLMHWFKKLPQKRFKQLVERLQLFITTRLFPAKPEELPPMAKCSWWIPSATKVLSLLNAANSISSAPIIPFTDFYNLTLDHIDFMEDYHTWQVHGNSNRFTFCQFPFILSTVVKKAIIQRDSEQQMISMARQTLVDKVSRRQRVDMSLLFLNIKVRRLQLVSDSLDELSRKRADLKKKLKVTFVGEAGLDMGGLTKEWFLLLIRQIFHTDYGMFTYVKESQCYWFSSWKCDNYSEFRLVGALMGLAVYNSITLDIRFPPCVYKKLLTPPIVPCDLDTPVGMATLTLDDLQQIMPDLAHGLGELLSYEGNVEEDFYTTFQVFQEELGVVKAYNLKPGGDKIPVTNLNRKEYVQLYIDFLLNKSIYRQFAAFYHGFHSVCASNALMLLRPEEVEILVCGSPNLDMGSLQRVVQYEGYSKTDPTIRAFWDVVLAFPLELQKKLLHFTTGSDRVPVGGMADLNFKISKIDVSTDWLPVSHTCFNQICLPPYKSKKELRQKLTIAISNAEGFGLE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .* * * :*::****:. *:**.* :.::.**:*::. *:*:. .:* .: * :* :::**: *** *****:* *::. ..*:*. :.** :* :.**.*:*::*:*:. :*:** ** **:*:**** *** ****:*.*.********:* ::** *:*:**:** * **:**********:***************:*:****:. .:*************:*.*******:**:***.**:******** *:: *********:**::**:******:***:***:**.: .*::*:***** ******:**:***** .***:**:***:**::* ..** ***********.:***:********** **.:****:**** :*********:***************************************.******* *:*:*:****:************ ******************* *****:**::*.* . ***:..:*:*** *:**:***** ****:*********:********:*::*:**********.*** **:****** *********:****** ***************************:*** :*** .**:**:*** **: ******.***:***************************** :.**: ***:******:*********:*:*** *.***:******", "identical_positions": 536, "similar_positions": 153, "identity": "69.07%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100405-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NSI8-1", "uniprot_id": "SANBR_HUMAN", "id": "Q6NSI8-1", "name": "SANT and BTB domain regulator of class switch recombination", "aln": "------------------MSRGYSENNNFLNNNNQMVLDMILYPLIGIPQTINWETIARLVPGLTPKECAKRFDELKSSGSSP-VDNQYNSLMAAGESPVETLATYIKSSLLDIHGEFQETPVGHDAVSKTGRHSIASTRNCSSESENCTTHNGGEMTEESEGPNMVIHVCDEAKNLKEDFTCPRDLLISEMKYFAEYLSMDAQRWEEVDISVHCDVHIFNWLIKYIKRNTKEN---KDCEMPTLEPGNVISILISSEFLKMDSLVEQCIQYCHKNMNAIVATPCNMNCINANLLTRIADLFSHNEVDDLKDKKDKFKSKLFCKKIERLFDPEYLNPDSRSNAATLYRCCLCKKLLTKETERRIPCIPGKINVDRRGNIVYIHIRDKTWDVHEYLNSLFEELKSWRDVYWRLWGTINWLTCSRCYQAFLCIEFSHCQYHSETVVYPTAASSLNTVGTGIYPCCNQKVLRFDPTQLTKGCKVRDHMVTLRDQGEGGDL-PSCPTARMLDDLHKYRDVIVVPFSKDTVSDVGVGLCDEKGIECDVLLEPNTPWGPKTGELNAFLSLKNWTLQLKQQSLFSEEEEYTTGSEVTEDEVGDEEEVSKKQRKKEKPKKFTRQPKKQVSSPCAQRKEKALEKSASRDVSPFVMSMQKNKWDATRSLRFNQDAQREDDQRRMTEITGHLIKMRLGDLDRVKSKEAKEFAGGIYSRLEAQIKASVPVSARQSSSEKNTRSKSRFGQGRPA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68FF0-1", "uniprot_id": "SANBR_MOUSE", "id": "Q68FF0-1", "name": "SANT and BTB domain regulator of class switch recombination", "aln": "------------------MSRGYPENNNFLNNNNQMVLDMILYPLIGIPQTINWETVARLVPGLTPKECVKRFDELKSCGSSP-VDNQYNPLMATGEGPVETLATYIKSSLLDTQGDFQETPVDQDTVSKAGRHSIATTRNCSSESENCTARNAGEETGESEGPNMVIHVCDEAKSLKEDFICPRDLLISEMKYFAEYLSMDAQRWEEVDISVHCDVHIFNWLIKYVKRNTKES---KDCEIPALEPGNVISILISSEFLKMDSLVEQCIQYCHKNMNAIVAAPCNMNCINANLLTRIADLFTHNEIDDLKDKKDKFRSKLFCKKIERLFDPEYSNPDSRNNAATLYRCCLCKKLLTRETERRIPCIPGKINVDRHGNIIYIHIRDKTWDVHEYLNSLFEELKSWRDVYWRLWGTVNWLTCSRCYQAFLCIEFSHCQYHSEVVVYSSTVNSLNTVGTGIYPCCNQKVLRFDPTQLTKGCKVRDHMVVLHDQGENDDS-PSCPPAKILDDLHKHKDVIAVPFLKDAVSDPGVGSCDEKGLEYEILLEPNTPWGSKTGELNAFLSLKNWTLQLKQQSLFSEEEEYTTGSEVTEDEVGDEEEIAKKQRKKEKPKKFTKPPKKQLSSPCSQKKEKTLEKSTSRDVSPFVVSMQKNKWDASRSLRFNQDAQREDDQRRMSEITGHLIKMRLGDLDRVKAKESKEFAGGIYSRLEAQVRASVPVTARQNSSDKNQRSKSRFGQGRPA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7EXN1-1", "uniprot_id": "E7EXN1_DANRE", "id": "E7EXN1-1", "name": "", "aln": "MKEEHCFQRKPRIHLEQEMNRLCSVNNNFPYDNNLLVLDIVLSSLWASPQPINWENVAKLVPGFTPKECARRFEELKTTGSFPHVDEQCNPLTGAVSSPSESFSTYIKSNVLDITRDTGEPQSNQTTLSVSGLNVLPTGRGASIETEIADPAKNIEKTEENKSPNMVIHVCDEAKNLKQDFVCPRNLLVKEMRYFEEYLSVDPQRWDEVDISVHCDVQIFDWLMNYAKSHNTEQSHGKHTEKPKLEHSNVISILISSEFLKMETLVEECIQYCHKHMSAIIATPCNMNCINNNLAGRIADLFNHNEADDLKDKKDKFKSKLFQKKIERIFDHGYQNHDSPGNASTLYRCGLCLKLLTKETERKIPCVPNKINIDARGNIVFTHSRHKAWEVHEYVNCLYEELKSWVQVYWRIWGTINFLTCSRCKQAFLCTELGQCRYHPEAVVYPGIGADHRWHGLGVYPCCNQKVLRFDPSFMPKGCKIRDHIVSAADGGDCSDHNVNSTQTRILNDLLLHRDAVCVAESSEDLS---VGSENVPG--CDVMLEPGVLTAHRPKETTAFSLLKNWSLQLRQQSLLSEDEEYTTGSEVTEDEVGDEEDTSKKQAAK-KARKSGKPLKRQVSSPNFHRKEKSGEKAPSRDTTPFTVSIQKNKWDSNRSMRYNQDAQREEDQRRMEEIIANLTKMRFGDQEQTKFKDTKEPAGGLYSRLEAQFKASSQSSARQSSSEKTLRAKTRSGPSRPT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.* . **** :** :***::* .* . **.****.:*:****:*****.:**:***: ** * **:* *.* .: ..* *:::*****.:** : *. .: ::* :* : :.: *..* *:* . . : * * *.:.************.**:** ***:**:.**:** ****:*.***:**********:**:**::* * :..*. *. * * ** .**************::***:*******:*.**:*:******** ** ******.*** **********:**** *****:** * * ** .**:***** ** ****:****:***:*.***:* :***:: * *.*:*:****:*.*:****** :****:***:*:****** ***** *:.:*:**.*.***. . . * *:*************: :.****:***:* * *: .* ... :::*:** ::*.: *. .: :* ** : * :::***.. . :. * .** ****:***:****:**:******************: :*** * *.:* : *:*:*** ::***: **:.***.:**.:*:******:.**:*:*******:***** ** .:* ***:** ::.* *::** ***:*******.:** :***.**:*. *:*:* * .**:", "identical_positions": 410, "similar_positions": 184, "identity": "55.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100406-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VGT4-1", "uniprot_id": "Q9VGT4_DROME", "id": "Q9VGT4-1", "name": "UDP-glucuronosyltransferase", "aln": "----------MRWLLNSWLLLILALFGQSWGYSYLMISHTASKSHYAVCFALAKGLAAAGHEVTLVSPFPQRKPIKN---IIDVETPNIITVMGVYKARILENAKKPVLLR--YPRISLMGLDITESLLKEPKV---QELLKQNRT--FDGVICE---------TFMNDAHYG---FAEHFGAPLITLSSLGATGWTSDLVGTPSPP--SYVPHSLLRFGDRMNFWERAQNLGFQIYEFAYENLINLPRHEALYRKYFP--NNKQDFYRMRKDTSLVLLNNHVS-ISNPRPYSPNMIEVGGMHVNRKAPK--PLPQNIRKFIEEA-EHGVIYFSLGSNLNSKDLPENKRKAIVETLRGLKYR-VIWKYEEET---FVDKPDNVLISNWLPQDDILAHEKVIAFITHGGLLSTMESIYHGKPVVGIPFFGDQFMNMARAEQMGYGITVKYAQLTASLFRSAIERITSDPSFTERVKVISSQYRDQKETPLERAVYWVEHVTRHK--GAKYLRSACQDLNFIQYHNLDVLA-----TFFSVIG-LTVIFVFLLV--RFLVTIVNGFLYKPSSKLKIN-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT5-1", "uniprot_id": "Q9VGT5_DROME", "id": "Q9VGT5-1", "name": "UDP-glucuronosyltransferase", "aln": "----------MRTFT--LILGLLCSLGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVSVFPQKKPIPG---YTDVSVPNVIEVMGGDIGALWASIQKTYTQN--LIDHYQMGFRITRGLFEDSNF---QDFLKSNQS--FDAIICE---------TFYNDAHYG---LAEHFNAPLIGLATGGGLTFITDMVGSPAPA--SFVPHIMLPFNDHMSLYERLLNVAFLGYERVLLDYYFLPTQEKLYKEFFP--GNKRCFYKMRRNASLVLINQHVS-LSFPRPHSPNMIEVGGMHIDGKWN---PLPEKIERFINES-EHGAIYFSMGSNLKTKDLPPSKVQEILKALGGLKQR-VLWKFELDN---LPNKPENVYISDWFPQTDILAHPKIMAFVTHGGMLSTTESIYHAKPVIGLPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQGISFRYRDQQQTPIENAIYWVEHVTRHQ--GAAYLKSAAQRLNWWQYHNVDVLL-----IIFVVMVLLLIVLPITIY--KLLKKLLLKGERTQSTKVKRN-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT2-1", "uniprot_id": "Q9VGT2_DROME", "id": "Q9VGT2-1", "name": "UDP-glucuronosyltransferase", "aln": "-----------MLASGLFYLIILLFPGFLYGARILALFPVPSHSHYYHALPYLKNLASLGHEITSVSPFPSEEPVKN---IYDIYVPEVLNSFDEL-LKQMTTPKNTWEF---FDATNEFVYNITKDVFNNDGV---RREILRPGKAQFDLIIVD---------IWKYDAFYS---LAAYFEAPIIGLAPCGIDWKIDEMVGNPSPM--SYLQSPSSYLYNLDTFGGRVAHVVEVAISWFNWHWRYEQKHEALYKKYFPKIAETKPLSEISQDIALVLVNQHFT-LGPPRPYVPNVIEVGGMHIDEQP---KALAQDLEDFIQGSGEHGVIYFSLGTNVRTKNMVDDRKRILIEAFGSLPQR-VLWKFEDEE---LQDIPSNVLVRKWLPQQDLLAHPKVKLFITHGGMQSTIESIHYGKPMLGLPFFYDQFTNVDHIKKHGFCLSLNYHDMTSDELKATILQLLTEKRFEVTARIAGARYRDQPMKPLETAVWWTHYVLRHK--GAPHMRVAGRKLSFFTHHSLDVLGTVLLVILLVIIAILLIIV-FSVC--KISKNISTRLVVKKQRKQKVR-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT1-1", "uniprot_id": "Q9VGT1_DROME", "id": "Q9VGT1-1", "name": "", "aln": "-------MPMSMLVLRLIVLVVALLPVLLEGARILGVFPIPSHSHYYHALPYLKKLASLGHEITSVSPFPLKEPVAN---IHDIPVPELFDNIEEI-VGNLTNRKGTWNE---FEYINQYTLGLVEKVLENDGV---RREILQPESLQFDLIIVD---------LWRLDALYG---LAAYFDAPIIGIASYGTDWKIDELVGNVSPL--AYLQSPSFNWFDLDTYGGRLGHFVDQSMAWINWHWRHEERHEAVYRKYFPKIADKRSLSEITRNFALILVNQHFT-MAPPRPYVPNIIEVGGMHVDQQP---KALPQDLEDFIQGAGEHGVIYFSLGTNVRSRNLSKDRRKILIDTFASLPQR-ILWKFDADE---LSDVPSNVLISPWFPQQDILAHPNVKLFITHGGLQSTVECIHRGVPMLGLPFFYDQFRNMEHIKAQGIGLVLNYRDMTSDEFKDTIHQLLTEKSFGVKAKRTADRYRDQPMNPLDTAIWWTHYVLRHK--GAPHMRVAGRNLDFITYHSLDVLG----TFLLAVWAILSIVV-LCAI--KLLRAILKSKKGNISPKQKIN-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9X9-1", "uniprot_id": "Q9V9X9_DROME", "id": "Q9V9X9-1", "name": "UDP-glucuronosyltransferase", "aln": "--------------MPPIFLLVCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSPYPQREPFRN---IHDIPVPEVFENFNEV-LRIASTPRSTWQS---SDFINEYVLNLTKTVLNNEGV---RRDILGPQKPHFDLVIMD---------LWRMDVLSG---LAAYFDAPIIGMASYGTDWKIDELMGNVSPI--SYLQSPSSRFYDLEAYGERLLHLMERTFSYMNYKWRHVRKQETLYSQFFPSVAERKPLSEISRNFDLVLVNQHFT-LGPPRPYVPNMIQVGGLHVDHST---EALSAELDHFIQGAGESGVIYFSLGTNVKSKSLSEDRRKVLLETFASLPQR-IVWKFEDEL---LPGKPPNVFISKWFPQQAILAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEFRSTIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHK--GAAHMQVAGKDLGFVRYHSLDVFG----TFLVGALVILGIVTYLLVM--TLRKCLFLIKRGKCEAIKKIQ-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT0-1", "uniprot_id": "Q9VGT0_DROME", "id": "Q9VGT0-1", "name": "UDP-glucuronosyltransferase", "aln": "-----------MLALRIGFLLLT-LPASMQAARILAIFPFPGPSQYINVVPYLKELANRGHQVTSVNAFPQKKPVVN---FRDVFIPDVFNNYKEL-INELSGPMNLWQE---NNFINKFFVSVTRCVLTNKEV---TETLLPPGKDHFDLIIVE---------ALRSDAYYG---FAAHFNAPIIGISTFGTDWNIDALVGNESPL--SYTPLATGGLTDRMTFLERLSNFVDTTVAWLNYRFVHMSEQEKMYAKYFPEASKRVQLTDLNRNFSLVLLNQHFS-LSFPRPYVPNMIEVGGLHISHKP---APLPKDLEEFIQGSGEHGVIYFSLGSNVLSKDLPADRKDLILKTFASLPQR-VLWKFEDDK---LPGKPSNVFISKWFPQPDILAHPKVKLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQQELKETIEILLKEPRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHK--GAYHMRVAGQDLGFFAYHSLDVIG----VLLGGALLLVAIIV-------GVLGKLTDFGNAKKKLKSK-------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGS9-1", "uniprot_id": "Q9VGS9_DROME", "id": "Q9VGS9-1", "name": "", "aln": "MGGIFSVTGLGILLIGLIWLFAANADEGVQSSRILAVFPFPGRSQYIFAEQFMKELAHRGHNVTVINTFGSDKNEPN---FRVIGAKKIHEIMAAFGNADYTQTASQWQM---LTMTTQFLNLLTTSILDDAAV---KDLLNSGEK--FDLVIME---------AVQTEALFG---LIQHFGAETIGISSYGTDTHIDELMGNISPL--SYNPLLLSSRTEQMDFKDRVMNVFEASVMWLHKRIVHLPSQRDLYAKYFP--TARKSLDEVLDSFALMLLGQHFS-LSYPRPYLPNMIEVGGLHLQQKRK-VQPLAKELSEFVEQS-EKGVIYFSMGSNIKSKDLPPSTRKMLMQTFASVPQR-VLWKFEDDQ---LPEKPDNVFISKWFPQPDILAHPNVKLFITHGGLLSTIESIYFGKPILGLPIFYDQHLNVQRAKQVGYGLSADIWSVNATELTPLIQELLSNPSYAAAAQTKSKLFRDQKETALERAIWWTEYVLRHK--GAKHLRCASRDLDFIQFHGLDTWG----LLIAITFVSLLIVVILIKCLQRVFVSLISKIRKNRAEASKLKTQ---------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT8-1", "uniprot_id": "Q9VGT8_DROME", "id": "Q9VGT8-1", "name": "UDP-glucuronosyltransferase", "aln": "------MRLLTVIAIVFCALSAKPLES--ESAKILATLPFPGRSQYIFVESYLKALAAKGHQVTVINAFK-NKETPN---MRFIEALKAHEFADEM--MSLLNVPLLWQQ---LNAMDYILNKFIDVTMEDEGV---QRLLNSGET--FDLVLAE---------MLHMEPMYA---FAQHFNATLVGFSSFGTDRTIDEAAGNISPI--SYNPLVTSPRTDRMTFLERLENHYEVIVEDIHRHFVHLPHMRNVYKKYFP--NAKKTLEEVMDSFSLILLGQHFS-LSYPRPYLPNMIEVGGMHISHKP---KPLPEDIKQFIEGS-PHGVIYFSMGSNVKSKDLPQETRDTLLKTFAKLKQR-VLWKFEDDD---MPGKPANVLIKKWYPQPDILAHPNVKLFISHGGLLSSTESVYFGKPILGLPCFYDQHMNVQRAQRVGFGLGLDLNNLKQEDLEKAIQTLLTDPSYAKASLAISERYRDQPQSAVDRAVWWTEYVIRHN--GAPHLRATSRDLNFIQLNSLDTLA----VILAVPLLLALLIVTLS-------CKLLGGKKQKCLHADKLKKH---------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCL4-1", "uniprot_id": "Q9VCL4_DROME", "id": "Q9VCL4-1", "name": "", "aln": "------MRLRYCWLTLSLCLLLQH--DRAQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLITPIG-MPNDIEG--VRHIRVAQLNERIKEMLESDQVLDFMINKWT--ESALTAKALFNASNDILSDPG---VQRMLHDKSESFDLIIME---------PSSLDALYG---LVEFYNATLMGLSSIRINWHTYELAGNPAPS--IYEPISPVGFSLETSLFSRVYNWIHIMEEKLVNYLILRPAQLHLFQKFFG--YSAQKMNELRSRFSLMLINSHYS-MGKVRANAPNIIEVGGLHLSEPPE---PSDEELQKFLDKA-DHGVIYFSMGNDILIKFLPENIQELLLQTFATLNES-IIWKSELLY---MPDKSDNVYVVEQAPQRHILNHPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEVMDINSLNKDTLTETIKHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNR--NITRMRLNLEEIPLIEYYRIDSILAFSLRFGLVAASLIFLVYTLF-LKYRIRLRRLHP-----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCL3-1", "uniprot_id": "Q9VCL3_DROME", "id": "Q9VCL3-1", "name": "", "aln": "------MRLGYAWLAFGLLLHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTPAD-YPAKIDG--VRHIRVPMLNQLMQNLMKNDQFFDALGDKWR--EGVLVSTIFYNVSHAILNNNG---VQMLMRDKSIRFDMIMVE---------ASHLDALYG---LAEFYNATLLGISCMHMTWHIDYLAGNLAPS--VYEPISPNGFALDNTFLSRWSNWIYITEEKLLERLVFRPAQVRLFKKFFG--YPAEKLDELRARFSVILVNSHFS-MGRVRANVPNIIEVAGVHLSEPPE---PCGAELQKYLDEA-EHGAIYFSMGQDILIKYLPENMQKQLLLVFLQMKQR-VIWKSELSM---LANKSENIYVMDKVPQRMVLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNADTLIETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNR--DTSHMRLNVEEIPLMRYYRLDSILTFGVRLGCVCGSLIFLGWRLY-QKNRNRHTRLQERERVIAQIQLGLSNYEVVS----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGS7-1", "uniprot_id": "Q9VGS7_DROME", "id": "Q9VGS7-1", "name": "UDP-glucuronosyltransferase", "aln": "----MFSGPGIAGLLLTVLLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLISAVT-IMPHIEG--VHHIRVPKLDMLMKILL--DFEYDTDLTKWT--EAQFLSEYFYNCSKFVLEDPG---VQELLRNASAKYSLIILE---------ASHNDALYG---FSQHFNAPLLGVAAYGSSWNIDFLVGNSAPS--VYEPMSALGYTSGLNLIEKWHNLIYITEERLVERFIYLPRQIDLYKQHFP--GATTSIHDLRRRFSLVLINQHFT-MGRVRSNVPNIVEVAGMHLDEKPY---PLDAELKKILDEA-EHGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQQ-VIWKTDYPE---MVNQSRNVFARTWFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLDFKNLFRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHK--GADHMRIAEQEMSLMQYYNVDVVSVLFGRIGLSAIIVIFLGWKLVSLATRHLEYRLNVPMVR-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGS8-1", "uniprot_id": "Q9VGS8_DROME", "id": "Q9VGS8-1", "name": "", "aln": "-------MFPPGRWLLPMFWLISNSICWIRSSRILVIAPFESHSQCMLVTPYIQALKDRGHQLTVIHAYKHCMHKIED--VTFIRIWYNNNVFLEFEESVGIASAN-NKWE--EISSMSSLMANATLNVLNNVE---VRALMKSR-ITFDAVVLE---------AGYSDVLYG---MAAHFSAQLIGICTCVADWNINNLVGFSTST--LTEPIMPFRAKYVKNVWDRIYNWLYTTEEWLLINLVFLPKQRLIHDHFFG--HLEKSFHEIRQDFALMLLNQHFS-LFRARPNVPGMVEVAGLHIPKEDP---QLPSDLQVFIDEA-EHGVILFSLGLEQDSKDLPRKTQEILVETFKSVPQR-VIWKFDGES---TMSLGTDIYHSKLLPQQAILAHPNVKLFISHCGMMSVIEAAYYAKPVLGLPSFFDQFRNLEIMKEEGVALELNINSLTVKELKDAIHSMINEPEYRESALAISQRFRDQPIHPLDAAIYWTEYIIRYK--GADHMKISQSQLKLFDYYSLDNFIMVGSRLSLVVALVFLVLSKSRRWLNHLSTSAKSFLPTKHLIRS--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1NUK4-1", "uniprot_id": "A0A8M1NUK4_DANRE", "id": "A0A8M1NUK4-1", "name": "UDP-glucuronosyltransferase", "aln": "----------MTHPSTHLRLFLLLCVLSRSHAGKLLVVPVDG-SHWINMKVLLVELHSKGHSITVVRASNSWYIEEQS--PLYTSITVENGEFDADFGEKFLPHLLKMQRQ--GKSFWTEMALADETYSRFTEI---HQEICKMTATMFENETLMNSLKDAAYDVVLTDPAFGGGVLLAHRLGLPLVFNVRWTMYGEAHFVIAPSPL--SYVPVSGLQLTDKMTFSQRVMNMMTYIMILYKNSKYFGSPYQELTQKYFG---PNVNFFSLLQDADLWLMRNDFT-FEFPRPTMPNVVYMGGFQCKPAKP----LPGDLEEFVQSSGEHGVIMMSLGAVFG--QLLSELNDEIAAAFAQLPQK-VIWRYTGPR---PANLGNNSLIVNWLPQNDLLGHPKTKLFVAHGGTNGLQEAIYHGVPIVGLPLAFDQPDNLSRMRAKGTAKIVDIATLDRAVFLEALKEVLHNPSYRENMQRLSKLHHDQPMKPLDRAIFWIEFVMRNK--GAPHLRTQSFRMSWIEYQSIDVIL--------TLMVMVLVFALVTAYMTKYFCLRLFRKKVKRE-----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VM44-1", "uniprot_id": "Q9VM44_DROME", "id": "Q9VM44-1", "name": "", "aln": "-MKRSPISWSLLWMGYTCIFLLADSPAPVESHHILGLFVNVHRSQLMVHLAVCRALLQRGHHLTLVTTLPLEEQEIQGN-VSHIYIPWQQPKEEVSSSDLILRLERMFRR-----------LEHSGDLLDLPEW---KMFLRNQPNTPYDLLLLG---------YHFNDHLLG---VAAHFNCPVAIVSTQQPTGFVNSLMGNPEER--WYVP-QPYDGQQRSGISAWVFGMWEKFMEILARRVLARIYRLHFPEPQYP------SFETMRRSVVLALSNHHMISEGPIAPLIPSMVDIGGIVLEQQLD--------KTPLEISAGNRSLIIFSLGTRFTWRKSTKELVRTFTKAFAQFPDYDIYWTYDGPNGSAISLDYPHLKVAKWWPQTQMWQSGKVRLFITHGGKGSVSEALFYGVPMLGLPLIGDQRDNLQRMQSKNWGLTLSTNNLTHWKLAKAITRMLSDSSYGETILKASQLYRDRPVSPSDLVTYWIEYIVRHK--GAKNLHNPARQLNIIEYHSIDVYFIVYGLLILTIAILRKVNSLL-------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9I7T3-1", "uniprot_id": "Q9I7T3_DROME", "id": "Q9I7T3-1", "name": "", "aln": "----------MRALCLLPVFVLLGRFCSLEAANILCLVSTAKHNNPGWSKPLFDALLANGHSLLVISTAPNPEPKKQVDGLVYYHLPNEYDVMKRHFLLEEPREYISMVTLNQLLVWYEVLLGSCRALLNSDTMSSKRPELTAQLSMEYDLIITD--------VTQGIECLMDS--VSGWRSKPVLGLSAGKLTPDLMSLLRAENTINAARIPHYISQVPKTMGFWNRLHNHIMYYAEPLIHLVITRPVLSELMK-----------TENAFPKLQLVLLNTHPT-LDYVQNLPPGVIEVGGLHIKNQTS---PLPTYIQEFTEKF-FDGIVYINMP---YIEYMNDQGLKAMYTMIHGNPNVAFIWNVEQLEQLPAKKPNLLTLHVNQSLQQDILAMQYVKGFLNHGDSFSLQEAIHYGVPVVVLPLKLEEFNNAQRVMERNLGVMLQVKEFNQSSLSDALTRILDEERFISALHQAQLKFRTRPQSALELAVWHAEQLIAEPRLFKHFAQTETLAQNFFVANSLDVLTVPLIVLLAAVVSLANLVYVLYTGGSKRQQTLEKAVLKKRKKSKKSSPQTFTPVNVTLKLETSELLEDLNNEILEGEEELLKGEEKPLEEKKED", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * ** : : : :. : . . . : * . *.:: :.*. . : :.: : : . * * : *: : . . *. . *:: :* :: * . . . : : : : : .: : . : . : . : :* : ", "identical_positions": 15, "similar_positions": 57, "identity": "2.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100406-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VGT4-1", "uniprot_id": "Q9VGT4_DROME", "id": "Q9VGT4-1", "name": "UDP-glucuronosyltransferase", "aln": "----------MRWLLNSWLLLILALFGQSWGYSYLMISHTASKSHYAVCFALAKGLAAAGHEVTLVSPFPQRKPIKN---IIDVETPNIITVM--GVYKARILENAKKPVLLRYPRISLMGLDITESLLKEPKV-------------QELLKQNRT--FDGVICETFM--NDAHYGFAEHFGAPLITLSS--LGATGWTSDLVGTPSPPSYVPHSLLRFGDRMNFWERAQNLGFQIYEFAYENLINLPRHEALYRKYFP--NNKQDFYRMRKDTSLVLLNNHVS-ISNPRPYSPNMIEVGGMHVNRKAPK--PLPQNIRKFIEEA-EHGVIYFSLGSNLNSKDLPENKRKAIVETLRGLKYR-VIWKYEEET---FVDKPDNVLISNWLPQDDILAHEKVIAFITHGGLLSTMESIYHGKPVVGIPFFGDQFMNMARAEQMGYGITVKYAQLTASLFRSAIERITSDPSFTERVKVISSQYRDQKETPLERAVYWVEHVTRHK--GAKYLRSACQDLNFIQYHNLDVLA-----TFFSVIG-LTVIFVFLLV--RFLVTIVNGFLYKPSSKLKIN-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT5-1", "uniprot_id": "Q9VGT5_DROME", "id": "Q9VGT5-1", "name": "UDP-glucuronosyltransferase", "aln": "----------MRTFT--LILGLLCSLGYSSGYNYLMVLNSAGRSHFNVGHALAKGLVKAGHTITVVSVFPQKKPIPG---YTDVSVPNVIEVM--GGDIGALWASIQKTYTQNLIDHYQMGFRITRGLFEDSNF-------------QDFLKSNQS--FDAIICETFY--NDAHYGLAEHFNAPLIGLAT--GGGLTFITDMVGSPAPASFVPHIMLPFNDHMSLYERLLNVAFLGYERVLLDYYFLPTQEKLYKEFFP--GNKRCFYKMRRNASLVLINQHVS-LSFPRPHSPNMIEVGGMHIDGKWN---PLPEKIERFINES-EHGAIYFSMGSNLKTKDLPPSKVQEILKALGGLKQR-VLWKFELDN---LPNKPENVYISDWFPQTDILAHPKIMAFVTHGGMLSTTESIYHAKPVIGLPIFSDQFFNMAHAEQNGYGIMLDFKTLNAVEFRKAIERITSEPSYTKVVQGISFRYRDQQQTPIENAIYWVEHVTRHQ--GAAYLKSAAQRLNWWQYHNVDVLL-----IIFVVMVLLLIVLPITIY--KLLKKLLLKGERTQSTKVKRN-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT2-1", "uniprot_id": "Q9VGT2_DROME", "id": "Q9VGT2-1", "name": "UDP-glucuronosyltransferase", "aln": "-----------MLASGLFYLIILLFPGFLYGARILALFPVPSHSHYYHALPYLKNLASLGHEITSVSPFPSEEPVKN---IYDIYVPEVLNSF--DEL-LKQMTTPKNTWEF-FDATNEFVYNITKDVFNNDGV-------------RREILRPGKAQFDLIIVDIWK--YDAFYSLAAYFEAPIIGLAP--CGIDWKIDEMVGNPSPMSYLQSPSSYLYNLDTFGGRVAHVVEVAISWFNWHWRYEQKHEALYKKYFPKIAETKPLSEISQDIALVLVNQHFT-LGPPRPYVPNVIEVGGMHIDEQP---KALAQDLEDFIQGSGEHGVIYFSLGTNVRTKNMVDDRKRILIEAFGSLPQR-VLWKFEDEE---LQDIPSNVLVRKWLPQQDLLAHPKVKLFITHGGMQSTIESIHYGKPMLGLPFFYDQFTNVDHIKKHGFCLSLNYHDMTSDELKATILQLLTEKRFEVTARIAGARYRDQPMKPLETAVWWTHYVLRHK--GAPHMRVAGRKLSFFTHHSLDVLGTVLLVILLVIIAILLIIV-FSVC--KISKNISTRLVVKKQRKQKVR-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT1-1", "uniprot_id": "Q9VGT1_DROME", "id": "Q9VGT1-1", "name": "", "aln": "-------MPMSMLVLRLIVLVVALLPVLLEGARILGVFPIPSHSHYYHALPYLKKLASLGHEITSVSPFPLKEPVAN---IHDIPVPELFDNI--EEI-VGNLTNRKGTWNE-FEYINQYTLGLVEKVLENDGV-------------RREILQPESLQFDLIIVDLWR--LDALYGLAAYFDAPIIGIAS--YGTDWKIDELVGNVSPLAYLQSPSFNWFDLDTYGGRLGHFVDQSMAWINWHWRHEERHEAVYRKYFPKIADKRSLSEITRNFALILVNQHFT-MAPPRPYVPNIIEVGGMHVDQQP---KALPQDLEDFIQGAGEHGVIYFSLGTNVRSRNLSKDRRKILIDTFASLPQR-ILWKFDADE---LSDVPSNVLISPWFPQQDILAHPNVKLFITHGGLQSTVECIHRGVPMLGLPFFYDQFRNMEHIKAQGIGLVLNYRDMTSDEFKDTIHQLLTEKSFGVKAKRTADRYRDQPMNPLDTAIWWTHYVLRHK--GAPHMRVAGRNLDFITYHSLDVLG----TFLLAVWAILSIVV-LCAI--KLLRAILKSKKGNISPKQKIN-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9X9-1", "uniprot_id": "Q9V9X9_DROME", "id": "Q9V9X9-1", "name": "UDP-glucuronosyltransferase", "aln": "--------------MPPIFLLVCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVSPYPQREPFRN---IHDIPVPEVFENF--NEV-LRIASTPRSTWQS-SDFINEYVLNLTKTVLNNEGV-------------RRDILGPQKPHFDLVIMDLWR--MDVLSGLAAYFDAPIIGMAS--YGTDWKIDELMGNVSPISYLQSPSSRFYDLEAYGERLLHLMERTFSYMNYKWRHVRKQETLYSQFFPSVAERKPLSEISRNFDLVLVNQHFT-LGPPRPYVPNMIQVGGLHVDHST---EALSAELDHFIQGAGESGVIYFSLGTNVKSKSLSEDRRKVLLETFASLPQR-IVWKFEDEL---LPGKPPNVFISKWFPQQAILAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEFRSTIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHK--GAAHMQVAGKDLGFVRYHSLDVFG----TFLVGALVILGIVTYLLVM--TLRKCLFLIKRGKCEAIKKIQ-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT0-1", "uniprot_id": "Q9VGT0_DROME", "id": "Q9VGT0-1", "name": "UDP-glucuronosyltransferase", "aln": "-----------MLALRIGFLLLT-LPASMQAARILAIFPFPGPSQYINVVPYLKELANRGHQVTSVNAFPQKKPVVN---FRDVFIPDVFNNY--KEL-INELSGPMNLWQE-NNFINKFFVSVTRCVLTNKEV-------------TETLLPPGKDHFDLIIVEALR--SDAYYGFAAHFNAPIIGIST--FGTDWNIDALVGNESPLSYTPLATGGLTDRMTFLERLSNFVDTTVAWLNYRFVHMSEQEKMYAKYFPEASKRVQLTDLNRNFSLVLLNQHFS-LSFPRPYVPNMIEVGGLHISHKP---APLPKDLEEFIQGSGEHGVIYFSLGSNVLSKDLPADRKDLILKTFASLPQR-VLWKFEDDK---LPGKPSNVFISKWFPQPDILAHPKVKLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQQELKETIEILLKEPRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHK--GAYHMRVAGQDLGFFAYHSLDVIG----VLLGGALLLVAIIV-------GVLGKLTDFGNAKKKLKSK-------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGS9-1", "uniprot_id": "Q9VGS9_DROME", "id": "Q9VGS9-1", "name": "", "aln": "MGGIFSVTGLGILLIGLIWLFAANADEGVQSSRILAVFPFPGRSQYIFAEQFMKELAHRGHNVTVINTFGSDKNEPN---FRVIGAKKIHEIM--AAFGNADYTQTASQWQM-LTMTTQFLNLLTTSILDDAAV-------------KDLLNSGEK--FDLVIMEAVQ--TEALFGLIQHFGAETIGISS--YGTDTHIDELMGNISPLSYNPLLLSSRTEQMDFKDRVMNVFEASVMWLHKRIVHLPSQRDLYAKYFP--TARKSLDEVLDSFALMLLGQHFS-LSYPRPYLPNMIEVGGLHLQQKRK-VQPLAKELSEFVEQS-EKGVIYFSMGSNIKSKDLPPSTRKMLMQTFASVPQR-VLWKFEDDQ---LPEKPDNVFISKWFPQPDILAHPNVKLFITHGGLLSTIESIYFGKPILGLPIFYDQHLNVQRAKQVGYGLSADIWSVNATELTPLIQELLSNPSYAAAAQTKSKLFRDQKETALERAIWWTEYVLRHK--GAKHLRCASRDLDFIQFHGLDTWG----LLIAITFVSLLIVVILIKCLQRVFVSLISKIRKNRAEASKLKTQ---------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT8-1", "uniprot_id": "Q9VGT8_DROME", "id": "Q9VGT8-1", "name": "UDP-glucuronosyltransferase", "aln": "------MRLLTVIAIVFCALSAKPLES--ESAKILATLPFPGRSQYIFVESYLKALAAKGHQVTVINAFK-NKETPN---MRFIEALKAHEFA--DEM--MSLLNVPLLWQQ-LNAMDYILNKFIDVTMEDEGV-------------QRLLNSGET--FDLVLAEMLH--MEPMYAFAQHFNATLVGFSS--FGTDRTIDEAAGNISPISYNPLVTSPRTDRMTFLERLENHYEVIVEDIHRHFVHLPHMRNVYKKYFP--NAKKTLEEVMDSFSLILLGQHFS-LSYPRPYLPNMIEVGGMHISHKP---KPLPEDIKQFIEGS-PHGVIYFSMGSNVKSKDLPQETRDTLLKTFAKLKQR-VLWKFEDDD---MPGKPANVLIKKWYPQPDILAHPNVKLFISHGGLLSSTESVYFGKPILGLPCFYDQHMNVQRAQRVGFGLGLDLNNLKQEDLEKAIQTLLTDPSYAKASLAISERYRDQPQSAVDRAVWWTEYVIRHN--GAPHLRATSRDLNFIQLNSLDTLA----VILAVPLLLALLIVTLS-------CKLLGGKKQKCLHADKLKKH---------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCL4-1", "uniprot_id": "Q9VCL4_DROME", "id": "Q9VCL4-1", "name": "", "aln": "------MRLRYCWLTLSLCLLLQH--DRAQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLITPIG-MPNDIEG--VRHIRVAQLNERI--KEMLESDQVLDFMINKWTESALTAKALFNASNDILSDPG-------------VQRMLHDKSESFDLIIMEPSS--LDALYGLVEFYNATLMGLSS--IRINWHTYELAGNPAPSIYEPISPVGFSLETSLFSRVYNWIHIMEEKLVNYLILRPAQLHLFQKFFG--YSAQKMNELRSRFSLMLINSHYS-MGKVRANAPNIIEVGGLHLSEPPE---PSDEELQKFLDKA-DHGVIYFSMGNDILIKFLPENIQELLLQTFATLNES-IIWKSELLY---MPDKSDNVYVVEQAPQRHILNHPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEVMDINSLNKDTLTETIKHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNR--NITRMRLNLEEIPLIEYYRIDSILAFSLRFGLVAASLIFLVYTLF-LKYRIRLRRLHP-----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCL3-1", "uniprot_id": "Q9VCL3_DROME", "id": "Q9VCL3-1", "name": "", "aln": "------MRLGYAWLAFGLLLHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVTPAD-YPAKIDG--VRHIRVPMLNQLM--QNLMKNDQFFDALGDKWREGVLVSTIFYNVSHAILNNNG-------------VQMLMRDKSIRFDMIMVEASH--LDALYGLAEFYNATLLGISC--MHMTWHIDYLAGNLAPSVYEPISPNGFALDNTFLSRWSNWIYITEEKLLERLVFRPAQVRLFKKFFG--YPAEKLDELRARFSVILVNSHFS-MGRVRANVPNIIEVAGVHLSEPPE---PCGAELQKYLDEA-EHGAIYFSMGQDILIKYLPENMQKQLLLVFLQMKQR-VIWKSELSM---LANKSENIYVMDKVPQRMVLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNADTLIETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNR--DTSHMRLNVEEIPLMRYYRLDSILTFGVRLGCVCGSLIFLGWRLY-QKNRNRHTRLQERERVIAQIQLGLSNYEVVS----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGS7-1", "uniprot_id": "Q9VGS7_DROME", "id": "Q9VGS7-1", "name": "UDP-glucuronosyltransferase", "aln": "----MFSGPGIAGLLLTVLLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLISAVT-IMPHIEG--VHHIRVPKLDMLM--KILL--DFEYDTDLTKWTEAQFLSEYFYNCSKFVLEDPG-------------VQELLRNASAKYSLIILEASH--NDALYGFSQHFNAPLLGVAA--YGSSWNIDFLVGNSAPSVYEPMSALGYTSGLNLIEKWHNLIYITEERLVERFIYLPRQIDLYKQHFP--GATTSIHDLRRRFSLVLINQHFT-MGRVRSNVPNIVEVAGMHLDEKPY---PLDAELKKILDEA-EHGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQQ-VIWKTDYPE---MVNQSRNVFARTWFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLDFKNLFRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHK--GADHMRIAEQEMSLMQYYNVDVVSVLFGRIGLSAIIVIFLGWKLVSLATRHLEYRLNVPMVR-------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGS8-1", "uniprot_id": "Q9VGS8_DROME", "id": "Q9VGS8-1", "name": "", "aln": "-------MFPPGRWLLPMFWLISNSICWIRSSRILVIAPFESHSQCMLVTPYIQALKDRGHQLTVIHAYKHCMHKIED--VTFIRIWYNNNVF--LEFEESVGIASAN-NKWEEISSMSSLMANATLNVLNNVE-------------VRALMKSR-ITFDAVVLEAGY--SDVLYGMAAHFSAQLIGICT--CVADWNINNLVGFSTSTLTEPIMPFRAKYVKNVWDRIYNWLYTTEEWLLINLVFLPKQRLIHDHFFG--HLEKSFHEIRQDFALMLLNQHFS-LFRARPNVPGMVEVAGLHIPKEDP---QLPSDLQVFIDEA-EHGVILFSLGLEQDSKDLPRKTQEILVETFKSVPQR-VIWKFDGES---TMSLGTDIYHSKLLPQQAILAHPNVKLFISHCGMMSVIEAAYYAKPVLGLPSFFDQFRNLEIMKEEGVALELNINSLTVKELKDAIHSMINEPEYRESALAISQRFRDQPIHPLDAAIYWTEYIIRYK--GADHMKISQSQLKLFDYYSLDNFIMVGSRLSLVVALVFLVLSKSRRWLNHLSTSAKSFLPTKHLIRS--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VM44-1", "uniprot_id": "Q9VM44_DROME", "id": "Q9VM44-1", "name": "", "aln": "-MKRSPISWSLLWMGYTCIFLLADSPAPVESHHILGLFVNVHRSQLMVHLAVCRALLQRGHHLTLVTTLPLEEQEIQG-NVSHIYIPWQQPKE--EVSSSDLILRLERMFRR---------LEHSGDLLDLPEW-------------KMFLRNQPNTPYDLLLLGYHF--NDHLLGVAAHFNCPVAIVST--QQPTGFVNSLMGNPEERWYVP-QPYDGQQRSGISAWVFGMWEKFMEILARRVLARIYRLHFPEPQYP------SFETMRRSVVLALSNHHMISEGPIAPLIPSMVDIGGIVLEQQLD--------KTPLEISAGNRSLIIFSLGTRFTWRKSTKELVRTFTKAFAQFPDYDIYWTYDGPNGSAISLDYPHLKVAKWWPQTQMWQSGKVRLFITHGGKGSVSEALFYGVPMLGLPLIGDQRDNLQRMQSKNWGLTLSTNNLTHWKLAKAITRMLSDSSYGETILKASQLYRDRPVSPSDLVTYWIEYIVRHK--GAKNLHNPARQLNIIEYHSIDVYFIVYGLLILTIAILRKVNSLL-------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1NWW5-1", "uniprot_id": "A0A8M1NWW5_DANRE", "id": "A0A8M1NWW5-1", "name": "UDP-glucuronosyltransferase", "aln": "-----------MPSLPATLLAFLSILSLVFGGKVLVFP--LDGSHWVNMKVLIEELHTRGHNVTVLRASNSWYIKEESPFYTSITVYNSGGIE--KELFEEFSRNILVIRRQKRSFWTKLKLVSEVGAVFEEMHRNQLNLMGNIFKNKDLMDSLQTAKYDLLLTDPAV--GGGFF-LAYRLGLPLVLNVR--WTMHGEAHFEIAP-SPLSYIPVPGLELTDKMTFVQRVQNILVYMFSKFQKARTVSKHYRSFCEKYFG---SEINYKAILQDADIWLMRNDFT-FEFPRPTMPNIVYMGGFQCKPSKP----LPDDLEEFVKSSGDHGLIVMSLGTLFT--HLPEDITEEIAAAFAGLPQK-IIWRHTGPR---PVNIGDNTLLVDWLPQNDLLGHAKTKVFITHGGTNGIQEAIYHGVPILGLPLVFDQPDNLSRMKVRGTAKLLDIAELNRTMFLEALKEVLYNPSYKENIQRLSKVHHDQPMKPLDRAMFWIEFVMRNK--GASHLRTQSFRMSWIEYHSIDVILT------LLMILVLFCVLIYSIVKYTCLKVVFKKKVKTQ------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7T3-1", "uniprot_id": "Q9I7T3_DROME", "id": "Q9I7T3-1", "name": "", "aln": "----------MRALCLLPVFVLLGRFCSLEAANILCLVSTAKHNNPGWSKPLFDALLANGHSLLVISTAPNPEPKKQVDGLVYYHLPNEYDVMKRHFLLEEPREYISMVTLNQLLVWYEVLLGSCRALLNSDTMSSK----------RPELTAQLSMEYDLIITDVTQGIECLMDSVSGWRSKPVLGLSAGKLTPDLMSLLRAENTINAARIPHYISQVPKTMGFWNRLHNHIMYYAEPLIHLVITRPVLSELMK-----------TENAFPKLQLVLLNTHPT-LDYVQNLPPGVIEVGGLHIKNQTS---PLPTYIQEFTEKF-FDGIVYINMP---YIEYMNDQGLKAMYTMIHGNPNVAFIWNVEQLEQLPAKKPNLLTLHVNQSLQQDILAMQYVKGFLNHGDSFSLQEAIHYGVPVVVLPLKLEEFNNAQRVMERNLGVMLQVKEFNQSSLSDALTRILDEERFISALHQAQLKFRTRPQSALELAVWHAEQLIAEPRLFKHFAQTETLAQNFFVANSLDVLTVPLIVLLAAVVSLANLVYVLYTGGSKRQQTLEKAVLKKRKKSKKSSPQTFTPVNVTLKLETSELLEDLNNEILEGEEELLKGEEKPLEEKKED", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . * ** : : . : :. :: . . : * . *.:: :.*. . : :.: : : . * * : *:.: . . *. . *:: :* :: * . . . : : : : : .: : . : . : . : :* ", "identical_positions": 15, "similar_positions": 59, "identity": "2.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100406-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W2J4-1", "uniprot_id": "Q9W2J4_DROME", "id": "Q9W2J4-1", "name": "UDP-glucuronosyltransferase", "aln": "------MSLKSALHIFLLSLVALQQLELGTGSRILAAFFFPGKSHFMMTNAIIRELVKQGHEVTFIT-PFSLAKEKLGSNYKEIVIP-QYDFWPEIKEMTNKNTVLEMTDLPTFAFLRMVNVMGIHTTDFALEQPEIQAVINEKNKIG------KYDLLLAEQFF--NEGALILGHLYQIPTITISTFGNANHLSQLFGVVSPW--SYVPHAYMPYTDRMTLWERIGNVAMSAAEDLVREFSYYPGQDAVLKKHFSKLLDRVPTIKELERNISAILLNSYMP-LASSRPMAYNMIPVGGLHIQPPK---ALPEHLQKFLDGA-THGAIYFSLGSQVRSADLPPEKLKVFLEVFGSLKQR-VLWKFED---ESLPNLPANVKVQSWLP--QGDILAHPNVKVFIAHGGLFGTQEAVYNGVPILGMPVYCDQHQNINQGKSAEYALGLDYRKVTVEELRGLLMELIENPKYRNNIKKASRIFRDRPLGAMDTAIYWINYVIEHR--GAPHLVAAGVHLPWYQFYLLDIVGLGLAVILLPIVVLILICR------RSSKPKSTPTKKKTKKN----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VDA5-1", "uniprot_id": "Q9VDA5_DROME", "id": "Q9VDA5-1", "name": "UDP-glucuronosyltransferase", "aln": "-------------MILFMKLLFVCLLGTGDGARILAPFFLPVKSHFMMTDAIIRELVKRGHEVTFIT-PLSLAKENLGPNYREILLP-KYDTWADISAMMKTKSALDMIDMSKLTHMRLAQHIGIKSTDFALAHPEVQELIYAKDKKG------KFDLLLVEQFH--NEGALMLGYIYEIPAITIATFAYANYFSQVFGFVNPL--SYVPNVFLSCTDRMSLWERLENVVISTAEDVVREVSYYPQQDAVIRKHFSSLLPRVPTVKQLEQNISVILLNSYMP-LTSPRPMSQNMISVGGLHILPPK---PLPEHIKNYLDNA-EHGAIYFSLGSQVRSADMPAEKLQIFLDVFASLKQR-VLWKFED---DQLPNLPDNVKVEKWLP--QADILAHPNVKVFIAHGGLFGMQEAVYHAVPVLGMPFYFDQDINIKAGQAAGYAIGLDYRTISKDQLKSALHALLKDPKYQANMMKASRIFRDRPLGAMDTAMYWINYVVEHR--GAPHLVAAGVHLPWYQFYLLDVSAIILAITLLPLLTLYAVSR------NYKSFRGIRAQKKEAKTE---------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2J3-1", "uniprot_id": "Q9W2J3_DROME", "id": "Q9W2J3-1", "name": "UDP-glucuronosyltransferase", "aln": "-------MQFPLLFGLLLTGTLYSQLELAEGSKILAVYAFPGKSHFMMHTALIRELVESGHQVTMVT-AFSLEKEQLGSNYTEILIEPVYDFWHDVKLNFGAQHLFELTRMTNYDFLKMLEIIGLKTTEHALRQPKVRSLIHAEQKEG------VFDLLLAEQFY--QEAFLALAHLYKIPVVTTSTLGYENHMSQMMGLITPW--SFVPHGFMPFTDRMSFLERVKNSYASFYEDMDRLLNYFPKMDAVAREFFGPVLTEVPKVKHMERQISVMLLNSHAP-LTTARPTVDAMVPVGGMHIYPPK---PLPADMQALLDGA-TEGAIFFSLGSNVQSKDMPVEMLRLFLQVFGSLKQR-VLWKFED---ESISQLPDNVMVRKWLP--QADILAHRHVKVFITHGGLFGTQEGVHYAVPMLGIPFYCDQHLNMNKAVLGGYAISLHFQSITEEILRHSLDQLIHNVTYKENVQRVSDIFRDRPLEPRKSAVYWIEYVIRHR--GASHMRSAGLDLNWFQFYLLDVIAFVAIIALAGVMALSLAIR------LLMG--SNKKHRKAKQN----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCL4-1", "uniprot_id": "Q9VCL4_DROME", "id": "Q9VCL4-1", "name": "", "aln": "------MRLRYCWLTLSLCLLLQH--DRAQAANILGIFPYRHISPFFVMQPLVRTLATRGHNVTLIT-PIG-MPNDIEG-VRHIRVAQLNERIKEMLE----SDQVLDFMINKWTESALTAKALFNASNDILSDPGVQ-RMLHDKSE-------SFDLIIMEPSS--LDALYGLVEFYNATLMGLSSIRINWHTYELAGNPAPS--IYEPISPVGFSLETSLFSRVYNWIHIMEEKLVNYLILRPAQLHLFQKFFG--YSAQK-MNELRSRFSLMLINSHYS-MGKVRANAPNIIEVGGLHLSEPP--EPSDEELQKFLDKA-DHGVIYFSMGNDILIKFLPENIQELLLQTFATLNES-IIWKSEL---LYMPDKSDNVYVVEQAP--QRHILNHPNVRLFITNGGLLSVIEAVDSGVPMLGLPMFFDQFGNMRWVQLSGMAEVMDINSLNKDTLTETIKHMLANNSYYLKAKEISQFFKDRPMSPLDTAVWWTEYALRNR--NITRMRLNLEEIPLIEYYRIDSILAFSLRFGLVAASLIFLVY------TLF-LKYRIRLRRLHP-----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCL3-1", "uniprot_id": "Q9VCL3_DROME", "id": "Q9VCL3-1", "name": "", "aln": "------MRLGYAWLAFGLLLHLNLYLELGQAANILGVFPYRIPSPFQMVRPLIKALVERGHKVTMVT-PAD-YPAKIDG-VRHIRVPMLNQLMQNLMK----NDQFFDALGDKWREGVLVSTIFYNVSHAILNNNGVQ-MLMRDKSI-------RFDMIMVEASH--LDALYGLAEFYNATLLGISCMHMTWHIDYLAGNLAPS--VYEPISPNGFALDNTFLSRWSNWIYITEEKLLERLVFRPAQVRLFKKFFG--YPAEK-LDELRARFSVILVNSHFS-MGRVRANVPNIIEVAGVHLSEPP--EPCGAELQKYLDEA-EHGAIYFSMGQDILIKYLPENMQKQLLLVFLQMKQR-VIWKSEL---SMLANKSENIYVMDKVP--QRMVLAHPNLRLFITHGGLQSVMEAIDNGVPMLGLPLFFDQFNNIHRVQLAGMAKVLDPNDLNADTLIETIKELLENPSYAQRAKEMAASFRDRPMSPLDTAIWWTEYALRNR--DTSHMRLNVEEIPLMRYYRLDSILTFGVRLGCVCGSLIFLGW------RLY-QKNRNRHTRLQERERVIAQIQLGLSNYEVVS----------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGS7-1", "uniprot_id": "Q9VGS7_DROME", "id": "Q9VGS7-1", "name": "UDP-glucuronosyltransferase", "aln": "----MFSGPGIAGLLLTVLLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLIS-AVT-IMPHIEG-VHHIRVPKLDMLMKILL------DFEYDTDLTKWTEAQFLSEYFYNCSKFVLEDPGVQ-ELLRNASA-------KYSLIILEASH--NDALYGFSQHFNAPLLGVAAYGSSWNIDFLVGNSAPS--VYEPMSALGYTSGLNLIEKWHNLIYITEERLVERFIYLPRQIDLYKQHFP--GATTS-IHDLRRRFSLVLINQHFT-MGRVRSNVPNIVEVAGMHLDEKP--YPLDAELKKILDEA-EHGVIYFSMGLQLLDHWLPPGMRASMSDAFAQLKQQ-VIWKTDY---PEMVNQSRNVFARTWFP--QRAILNHPNVKLFITHAGLLSLIESVHYAVPLLCIPLFYDQFQNTKRMEKLGVARKLDFKNLFRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMSAMDTAIWWTEYILRHK--GADHMRIAEQEMSLMQYYNVDVVSVLFGRIGLSAIIVIFLGW------KLVSLATRHLEYRLNVPMVR-------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGS8-1", "uniprot_id": "Q9VGS8_DROME", "id": "Q9VGS8-1", "name": "", "aln": "-------MFPPGRWLLPMFWLISNSICWIRSSRILVIAPFESHSQCMLVTPYIQALKDRGHQLTVIH-AYKHCMHKIED-VTFIRIWYNNNVFLEFEE----SVGIASAN-NKWEEISSMSSLMANATLNVLNNVEVR-ALMKSR-I-------TFDAVVLEAGY--SDVLYGMAAHFSAQLIGICTCVADWNINNLVGFSTST--LTEPIMPFRAKYVKNVWDRIYNWLYTTEEWLLINLVFLPKQRLIHDHFFG--HLEKS-FHEIRQDFALMLLNQHFS-LFRARPNVPGMVEVAGLHIPKED--PQLPSDLQVFIDEA-EHGVILFSLGLEQDSKDLPRKTQEILVETFKSVPQR-VIWKFDG---ESTMSLGTDIYHSKLLP--QQAILAHPNVKLFISHCGMMSVIEAAYYAKPVLGLPSFFDQFRNLEIMKEEGVALELNINSLTVKELKDAIHSMINEPEYRESALAISQRFRDQPIHPLDAAIYWTEYIIRYK--GADHMKISQSQLKLFDYYSLDNFIMVGSRLSLVVALVFLVLS------KSRRWLNHLSTSAKSFLPTKHLIRS--------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT2-1", "uniprot_id": "Q9VGT2_DROME", "id": "Q9VGT2-1", "name": "UDP-glucuronosyltransferase", "aln": "-----------MLASGLFYLIILLFPGFLYGARILALFPVPSHSHYYHALPYLKNLASLGHEITSVS-PFPSEEPVKN--IYDIYVPEVLNSFDEL------LKQMTTPK-NTWEFFDATNEFVYNITKDVFNNDGVRREILRPGKA-------QFDLIIVDIWK--YDAFYSLAAYFEAPIIGLAPCGIDWKIDEMVGNPSPM--SYLQSPSSYLYNLDTFGGRVAHVVEVAISWFNWHWRYEQKHEALYKKYFPKIAETKP-LSEISQDIALVLVNQHFT-LGPPRPYVPNVIEVGGMHIDEQP--KALAQDLEDFIQGSGEHGVIYFSLGTNVRTKNMVDDRKRILIEAFGSLPQR-VLWKFED---EELQDIPSNVLVRKWLP--QQDLLAHPKVKLFITHGGMQSTIESIHYGKPMLGLPFFYDQFTNVDHIKKHGFCLSLNYHDMTSDELKATILQLLTEKRFEVTARIAGARYRDQPMKPLETAVWWTHYVLRHK--GAPHMRVAGRKLSFFTHHSLDVLGTVLLVILLVIIAILLIIV-FSVCKISKNISTRLVVKKQRKQKVR-------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT1-1", "uniprot_id": "Q9VGT1_DROME", "id": "Q9VGT1-1", "name": "", "aln": "-------MPMSMLVLRLIVLVVALLPVLLEGARILGVFPIPSHSHYYHALPYLKKLASLGHEITSVS-PFPLKEPVAN--IHDIPVPELFDNIEEI------VGNLTNRK-GTWNEFEYINQYTLGLVEKVLENDGVRREILQPESL-------QFDLIIVDLWR--LDALYGLAAYFDAPIIGIASYGTDWKIDELVGNVSPL--AYLQSPSFNWFDLDTYGGRLGHFVDQSMAWINWHWRHEERHEAVYRKYFPKIADKRS-LSEITRNFALILVNQHFT-MAPPRPYVPNIIEVGGMHVDQQP--KALPQDLEDFIQGAGEHGVIYFSLGTNVRSRNLSKDRRKILIDTFASLPQR-ILWKFDA---DELSDVPSNVLISPWFP--QQDILAHPNVKLFITHGGLQSTVECIHRGVPMLGLPFFYDQFRNMEHIKAQGIGLVLNYRDMTSDEFKDTIHQLLTEKSFGVKAKRTADRYRDQPMNPLDTAIWWTHYVLRHK--GAPHMRVAGRNLDFITYHSLDVLG----TFLLAVWAILSIVV-LCAIKLLRAILKSKKGNISPKQKIN-------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9V9X9-1", "uniprot_id": "Q9V9X9_DROME", "id": "Q9V9X9-1", "name": "UDP-glucuronosyltransferase", "aln": "--------------MPPIFLLVCLLPGYSEGARILAVFPLPSSSHYFFALPYLKSLASLGHEITSVS-PYPQREPFRN--IHDIPVPEVFENFNEV------LRIASTPR-STWQSSDFINEYVLNLTKTVLNNEGVRRDILGPQKP-------HFDLVIMDLWR--MDVLSGLAAYFDAPIIGMASYGTDWKIDELMGNVSPI--SYLQSPSSRFYDLEAYGERLLHLMERTFSYMNYKWRHVRKQETLYSQFFPSVAERKP-LSEISRNFDLVLVNQHFT-LGPPRPYVPNMIQVGGLHVDHST--EALSAELDHFIQGAGESGVIYFSLGTNVKSKSLSEDRRKVLLETFASLPQR-IVWKFED---ELLPGKPPNVFISKWFP--QQAILAHPNVKLFITHGGLLSTIESIHHGKPMLGLPCLFDQFRNMDHVRQVGLGLVLNIKQMTSEEFRSTIIRLLTNKSFEETARITAARYRDQPMKPMETAIWWTEYVLSHK--GAAHMQVAGKDLGFVRYHSLDVFG----TFLVGALVILGIVTYLLVMTLRKCLFLIKRGKCEAIKKIQ-------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT0-1", "uniprot_id": "Q9VGT0_DROME", "id": "Q9VGT0-1", "name": "UDP-glucuronosyltransferase", "aln": "-----------MLALRIGFLLLT-LPASMQAARILAIFPFPGPSQYINVVPYLKELANRGHQVTSVN-AFPQKKPVVN--FRDVFIPDVFNNYKEL------INELSGPM-NLWQENNFINKFFVSVTRCVLTNKEVTETLLPPGKD-------HFDLIIVEALR--SDAYYGFAAHFNAPIIGISTFGTDWNIDALVGNESPL--SYTPLATGGLTDRMTFLERLSNFVDTTVAWLNYRFVHMSEQEKMYAKYFPEASKRVQ-LTDLNRNFSLVLLNQHFS-LSFPRPYVPNMIEVGGLHISHKP--APLPKDLEEFIQGSGEHGVIYFSLGSNVLSKDLPADRKDLILKTFASLPQR-VLWKFED---DKLPGKPSNVFISKWFP--QPDILAHPKVKLFITHGGLLSTIESIHHGKPVLGLPFFYDQFLNVRRATQAGFGLGLDHTTMTQQELKETIEILLKEPRFAQIARQMSERYRDQPMSPLDTAIWWTEYVLRHK--GAYHMRVAGQDLGFFAYHSLDVIG----VLLGGALLLVAIIV-----GVLGKLTDFGNAKKKLKSK---------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGS9-1", "uniprot_id": "Q9VGS9_DROME", "id": "Q9VGS9-1", "name": "", "aln": "MGGIFSVTGLGILLIGLIWLFAANADEGVQSSRILAVFPFPGRSQYIFAEQFMKELAHRGHNVTVIN-TFGSDKNEPN--FRVIGAKKIHEIMAAFGN----ADYTQTA--SQWQMLTMTTQFLNLLTTSILDDAAVKDLLNSGEK---------FDLVIMEAVQ--TEALFGLIQHFGAETIGISSYGTDTHIDELMGNISPL--SYNPLLLSSRTEQMDFKDRVMNVFEASVMWLHKRIVHLPSQRDLYAKYFP--TARKS-LDEVLDSFALMLLGQHFS-LSYPRPYLPNMIEVGGLHLQQKRKVQPLAKELSEFVEQS-EKGVIYFSMGSNIKSKDLPPSTRKMLMQTFASVPQR-VLWKFED---DQLPEKPDNVFISKWFP--QPDILAHPNVKLFITHGGLLSTIESIYFGKPILGLPIFYDQHLNVQRAKQVGYGLSADIWSVNATELTPLIQELLSNPSYAAAAQTKSKLFRDQKETALERAIWWTEYVLRHK--GAKHLRCASRDLDFIQFHGLDTWGLLIAITFVSLLIVVILIK--CLQRVFVSLISKIRKNRAEASKLKTQ-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT8-1", "uniprot_id": "Q9VGT8_DROME", "id": "Q9VGT8-1", "name": "UDP-glucuronosyltransferase", "aln": "------MRLLTVIAIVFCALSAKPLES--ESAKILATLPFPGRSQYIFVESYLKALAAKGHQVTVIN-AFK-NKETPN--MRFIEALKAHEFADEM------MSLLNVP--LLWQQLNAMDYILNKFIDVTMEDEGVQRLLNSGET---------FDLVLAEMLH--MEPMYAFAQHFNATLVGFSSFGTDRTIDEAAGNISPI--SYNPLVTSPRTDRMTFLERLENHYEVIVEDIHRHFVHLPHMRNVYKKYFP--NAKKT-LEEVMDSFSLILLGQHFS-LSYPRPYLPNMIEVGGMHISHKP--KPLPEDIKQFIEGS-PHGVIYFSMGSNVKSKDLPQETRDTLLKTFAKLKQR-VLWKFED---DDMPGKPANVLIKKWYP--QPDILAHPNVKLFISHGGLLSSTESVYFGKPILGLPCFYDQHMNVQRAQRVGFGLGLDLNNLKQEDLEKAIQTLLTDPSYAKASLAISERYRDQPQSAVDRAVWWTEYVIRHN--GAPHLRATSRDLNFIQLNSLDTLAVILAVPLLLALLIVTLS---------CKLLGGKKQKCLHADKLKKH-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGT3-1", "uniprot_id": "Q9VGT3_DROME", "id": "Q9VGT3-1", "name": "", "aln": "-------MKPTAGQTGFLALLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIIS-PFELKKPIKN--IKDVPAKSILTSMQGR-I----ANLLQSSKEPIIKQIINFHEMGIEITELLLKEPSVIELMKSNQT---------FDAVISEVFL--NEAHFGFAEHFKAPLIGLGTFGAISWNTDLVGSPSPP--SYVPSALLKFSDRMSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKYFP--NNKQD-FYDMRKNTALVLLNQHVS-LSFPRPYSPNMIEVGGMHINRKR--QPLPKDILEFIEGA-EHGVIYFSMGSNLKSKTLPLEKRQALIDTFAQLKQR-VLWKFED---TDLPGKPANVFISDWFP--QDDILAHDNVLAFITHGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHK--GAKYLRSASQDLNFIQYHNLDAMLILYGGIIFVLYCIFLLIR--LVWRLLQELFIK-KDTSKPKQKAKRN-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VM44-1", "uniprot_id": "Q9VM44_DROME", "id": "Q9VM44-1", "name": "", "aln": "-MKRSPISWSLLWMGYTCIFLLADSPAPVESHHILGLFVNVHRSQLMVHLAVCRALLQRGHHLTLVT-TLPLEEQEIQGNVSHIYIPWQQPKEEVS---------------SSDLILRLERMFRRLEHSGDLLDLPEWKMFLRNQPNT------PYDLLLLGYHF--NDHLLGVAAHFNCPVAIVSTQQPTGFVNSLMGNPEER--WYVPQP-YDGQQRSGISAWVFGMWEKFMEILARRVLAR-----IYRLHFP--EPQYPSFETMRRSVVLALSNHHMISEGPIAPLIPSMVDIGGIVLEQQL-------DKTPLEISAGNRSLIIFSLGTRFTWRKSTKELVRTFTKAFAQFPDYDIYWTYDGPNGSAISLDYPHLKVAKWWP--QTQMWQSGKVRLFITHGGKGSVSEALFYGVPMLGLPLIGDQRDNLQRMQSKNWGLTLSTNNLTHWKLAKAITRMLSDSSYGETILKASQLYRDRPVSPSDLVTYWIEYIVRHK--GAKNLHNPARQLNIIEYHSIDVYFIVYGLLILTIAILRKVNS----------LL---------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E7EZQ8-1", "uniprot_id": "E7EZQ8_DANRE", "id": "E7EZQ8-1", "name": "", "aln": "------MNGQWFQVIWPITLTLLLPSVPVAQCGKVLVFPVDG-SHWVNMNILVEALSAKGHDVTVMRTASSCYIKEFSPHYTSINLKSKGGYNKEVLEQFASRIMHILRDGSTWGHLKLQADMWQSFLKIFEAEREMIVNMIEDQQLMQSLKDAKYDLILTDPNM--FGGVI-LGHYLKLPMVYNVRWAG-YNEAHFSIAPSPL--SYVPMPSLELSDRMSFLQRVYNVVMYIFIEIGAALVISPINDALAERFIG----PGTSFLSLVQGADLWLHRVDFV-FEYPRPTMPNVIYMAGFQCKPSK---PLPQDLEDFVQSSGDHGVIIMSLGT--LIDKLPDDVAEAIAEAFAELPQK-IIWRYKG---KRPSALGNNTLIMDWMP--QNDLLGHPKTRAFVAHGGTNGIQEAIYHGVPIIGFGLIFDQPDNLSKMRVRGAAKNVDFATMNKESFLTTVKEVLYDPSYRENMQRLSRLHKDVPVKPLDNAIFWIEFVMRHK--GAAHLRTESYKMPWYSYHSVDVILVLISAVSLIILSIYAVIR------YFCCRICMRKTKIKHE-----------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7T3-1", "uniprot_id": "Q9I7T3_DROME", "id": "Q9I7T3-1", "name": "", "aln": "----------MRALCLLPVFVLLGRFCSLEAANILCLVSTAKHNNPGWSKPLFDALLANGHSLLVISTAPNPEPKKQVDGLVYYHLPNEYDVMKRHFLLE---EPREYISMVTLNQLLVWYEVLLGSCRALLNSDTMSSKRPELTAQLS----MEYDLIITDVTQGIECLMDSVSGWRSKPVLGLSAGKLTPDLMSLLRAENTINAARIPHYISQVPKTMGFWNRLHNHIMYYAEPLIHLVITRPVLSELMKTENA------------FPKLQLVLLNTHPT-LDYVQNLPPGVIEVGGLHIKNQT--SPLPTYIQEFTEKF-FDGIVYINMPYIEYMNDQG---LKAMYTMIHGNPNVAFIWNVEQ--LEQLPAKKPNLLTLHVNQSLQQDILAMQYVKGFLNHGDSFSLQEAIHYGVPVVVLPLKLEEFNNAQRVMERNLGVMLQVKEFNQSSLSDALTRILDEERFISALHQAQLKFRTRPQSALELAVWHAEQLIAEPRLFKHFAQTETLAQNFFVANSLDVLTVPLIVLLAAVVSLANLVYVLYTGGSKRQQTLEKAVLKKRKKSKKSSPQTFTPVNVTLKLETSELLEDLNNEILEGEEELLKGEEKPLEEKKED", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * ** : : . :. :: . . : * :: :.*. . : :.: : : : . * . . * : *: : . . * *.: : :: * . : : :: : .: . . . : . :* : ", "identical_positions": 12, "similar_positions": 53, "identity": "1.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100408-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0U1RRY2-1", "uniprot_id": "A0A0U1RRY2_RAT", "id": "A0A0U1RRY2-1", "name": "", "aln": "MNVHQGSDGDWLLQPELSFLGDETLAATQEKESSSLVSSGLPSLTYPLAARNEDFALDSAPQPAASLQHPHIMPLPEDNKGSCFQSGSRRSREPFLVPERSGSGGLGFGG--SSQAPEKVTLLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYEIAEGISATVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIRCQDLSALLHELSNDGAHKQFDHYLEELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVAAGEDVLEDQEIMMHHPP----------------------------------QVDE-------LDRLNAPLAQMAPNDFQD--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CDD8-1", "uniprot_id": "KCD20_MOUSE", "id": "Q8CDD8-1", "name": "BTB/POZ domain-containing protein KCTD20", "aln": "MNVHQGSDGDWSLQPELSCLGDEALAATQEKEGSSLVSSGLHSVTYPLAARSEDLALDYASQP-ASLPHPHIMPLPEDNKGSCFQSGSKRSHEPFIVPERFGNSGLGFGGGAHSQAPEKVTLLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYVIAEGISATVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIRCQDLSALLHELSNDGAHKQFDHYLEELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVAAGEDVLEDQEIIMHHPP----------------------------------QVDE-------LDRLNAPLSQMAPNDFQD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z5Y7-1", "uniprot_id": "KCD20_HUMAN", "id": "Q7Z5Y7-1", "name": "BTB/POZ domain-containing protein KCTD20", "aln": "MNVHRGSDSDRLLRQEASCLVDDTLAVAQEKEANSLASSGPHNLTYPLGPRNEDLSLDYASQP-ANLQFPHIMPLAEDIKGSCFQSGNKRNHEPFIAPERFGNSSVGFGSNSHSQAPEKVTLLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYEIAEGISATVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIRCQDLSALLHELSNDGAHKQFDHYLEELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVAAGDDVLEDQEILMHHPP----------------------------------QVDE-------LDRLNAPLSQMASNDFQD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P4H9-1", "uniprot_id": "A0A8M9P4H9_DANRE", "id": "A0A8M9P4H9-1", "name": "", "aln": "MAEEHATARG----------------MTVGAEGGADVTKG----VWPAQPR----------------------PLSHD----------------------------------------RVTLVVDGTHFVVDPAVFTAYPDTVLGRMFGRARQHSFTRPNTKGEYEIAEGIGASIFRIILDFYRVGILHCPEGVSLAELREACDYLCINFDYNTVRCRDLSALLHELSNDGARRQFEVFLEELLLPAMVSSAQEGERECHIVVLTDDDTVDWDHDNPPPMGEEHSQIIYSTKLYRFFKFIENRDVAKAHLKERGLKNIRIGIEGYPTCKEKVKRRPGGKSEVIYSYLQRPFIQLSWEKEEGKSRHVDFQCVRSRSVPNLITAMGEGP--TRAGATPTP----------------------------------QVDE-------LDRLNGP----APPGLDQ--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E8K5-1", "uniprot_id": "Q0E8K5_DROME", "id": "Q0E8K5-1", "name": "", "aln": "MSNTPSLNSSSS---------NISSKAPLAQKQDTYSSDSSEEVLETAEERRRRILKERSRLN-----------RPQHNMSGGGAVPKHDIKSPCGASPSCQATGSGMGR--LPLPPERITMLVDGVRFTVEQSLLTAHPTTMLGTMFGSG--FQFAHTNERGEYDVADGISHLVFRAILEYYKSGVIRCPPTVSVPELKEACDYLLIPFDATTVRCQNLRGLLHELSNEGARQQFELFLEDLILPLMVASAQRGDRECHVVVLLEDDMVEWDEEFPPQMGEEYCQTVHSTAMHRFFKYIENRDVAKQVMKDRGLKKIRCGIEGYPTHKEKIRRRPGGRAEVIYSYVQRPFIHMSWEKEEAKSRHVDFQCVKSKSVTNLAEANADPPLELDASGNPIPPIAVANPHPNNAELAAGMAVAPAAIGVAGPAVVVAVDEAAGGVVMLNELDQAAIAVAVGIVDENM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . . : .: :.. . * ... ::*::***.:*.*: ::**:* *:** *** . ..*::.* :*** :*:**. :** :*::*: *::.** :*:.:*:::**** * ** .*:**::* .*******:**::**: :**:*:** **..*:.*:****:*** ::* *:**.: ** ****:.* ::*: ::****:******** :*:****:** ******* ***::*****::****.*:*****::******.**********:*:*:.** * : * *** *:.*: . * .:: ", "identical_positions": 156, "similar_positions": 105, "identity": "33.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100408-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96NA2-1", "uniprot_id": "RILP_HUMAN", "id": "Q96NA2-1", "name": "Rab-interacting lysosomal protein", "aln": "-------MEPRRAAPGVPGWGSREAAGSASAAELVYHLAGALGTELQDLARRFGPEAAAGLVPLVVRALELLEQAAVG------------PAPDSLQVSAQP--------------------------------AEQELRRLREENERLRRELRAGP-------QEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQRKKIKAKMLGTPEEAESSEDEAGPWILLSDDKGD-----HPPPPESKIQSFFGLWYRGKAESSEDETSSPAPSKLGGEEEAQPQSPAPDPPCSALHEHLCLGASAAPEA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5ND29-1", "uniprot_id": "RILP_MOUSE", "id": "Q5ND29-1", "name": "Rab-interacting lysosomal protein", "aln": "-------MEPRRAAPRLPSQAS-SSVGAGSAAELVYHLAGALGTELQGLARRFGPDAAAGLVPLVVRALELLEKAAVG------------PAPDSLQVSAQQ--------------------------------AEVELRRLREENQRLRQELGSGP-------QEERALLRQLKEVTDRQRDELRAHNRDLQRRSQETEALQEQLQRLLLINSELRHKLAAVQTQLRAAQDRERERQIAQDGSSQLAKEQS------------LEPDAATS--------DDPVDTQKQPGNLPEAVQCGFSREELKQILQERNELKANVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVKKQRRKIKAKMLGTPEEAESSEDEDGSWLLLSNDKED-----VPLVPESRIQNFFGLWYRGETEAPEAETSNPASSSLQKGEET-PQQPHLQP----------VNSPPAPNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F6M9-1", "uniprot_id": "E7F6M9_DANRE", "id": "E7F6M9-1", "name": "RILP-like protein 2", "aln": "METCVIAVEENQNDTAKEAHSCFDRTFSSMTVDDVYEIAKVVGAEVEKLIDSYGKSSVEGLVSRIVKVLELLESFAARNQSHKCKEEELLKAFETLQLQQQKKRHVKECEESSSSAESRDWHQTEKKLKNNLEVLQSQVHQLKEENQELLTRIQCTHSKEDRTQRQEREVMLKLKEVVDKQRDELRAKVQEISSMSKEVEALQEQQERLMKINAELRHKQNIIHTQMKSAVERKADLEADLCEKQKEIQRLN------------SQLERSSVHTAAETSSSAIDLTDKMIIDLKDPNRPCFTKQEVRDMLFERNELKANLFLVKEELAYYQREILNDERCPGFLLDAVRSAIKKQRTVIKSKMLGIPVSECSTDETDGPLFERSGNEDNDTDSTDSRPQESRIRNLFGFLTRPSLTRSSVSPSSSLPASSSTWEIIDPDEQGVEE-----------EAETLSSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .: . . .. . . :. :.: **.:* .:*:*:: * :* .:. ***. :*:.*****. *. * ::**:. * : ::::*:***:.* .: . ::** :: :****.*:*******: ::: .:*.****** :**: :*:***** ::**:::* :*: : : :. : : :: . : : :. : *:::*..::* *******::**:******:***:*.*.* **:**:*:: *::*** **:**** * . *::: *. : *.:: : . **:*:.:**: * . .. ..*.. .:. * *:. : : . ..:", "identical_positions": 112, "similar_positions": 140, "identity": "24.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100408-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y2X7-1", "uniprot_id": "GIT1_HUMAN", "id": "Q9Y2X7-1", "name": "ARF GTPase-activating protein GIT1", "aln": "MSRKGPRAEVCADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASNGANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLVECQYELTDRLAFYLCGRKPDHKNGHYIIPQMAD---------SLDLSELAKAAKKKLQALSNRLFEELAMDVYDEVDRRENDAVWLATQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLIIDILSEAKRRQQGKSLSSPTDNLELSLRSQSDLDDQHDYDSVASDEDTDQEPLRSTG--ATRSNRARSMDSSDLSDGAVTLQEYLELKKALATSEAKVQQLMKVNSSLSDELRRLQREIHKLQAENLQLR---------QPPGPVPTPPLPSER---------AEHTPMAPGGSTHRRDRQAFSMYEPGSALKPFGGPPGDELTTRLQPFHSTELEDDAIYSVHVPAGLYRIRKGVSASAVPFTPSSPLLSCSQEGSR-HTSKLSRHGSGADSDYENTQSGDPLLGLEGKRFLELGKEEDFHPELESLDGDLDPGLPSTEDVILKTEQVTKNIQELLRAAQEFKHDSFVPCSEKIHLAVTEMASLFPKRPALEPVRSSLRLLNASAYRLQSECRKTVPPEPGAP-VDFQLLTQQVIQCAYDIAKAAKQLVTITTREKKQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68FF6-1", "uniprot_id": "GIT1_MOUSE", "id": "Q68FF6-1", "name": "ARF GTPase-activating protein GIT1", "aln": "MSRKGPRAEVCADCSAPDPGWASISRGVLVCDECCSVHRSLGRHISIVKHLRHSAWPPTLLQMVHTLASNGANSIWEHSLLDPAQVQSGRRKANPQDKVHPIKSEFIRAKYQMLAFVHKLPCRDDDGVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQTLQAELLVVYGADPGSPDVNGRTPIDYARQAGHHELAERLVECQYELTDRLAFYLCGRKPDHKNGHYIIPQMADRSRQKCMSQSLDLSELAKAAKKKLQALSNRLFEELAMDVYDEVDRRENDAVWLATQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLIIDILSEAKRRQQGKSLSSPTDNLELSARSQSELDDQHDYDSVASDEDTDQEPLPSAG--ATRNNRARSMDSSDLSDGAVTLQEYLELKKALATSEAKVQQLMKVNSSLSDELRRLQREIHKLQAENLQLR---------QPPGPVPPPSLPSER---------AEHTLMGPGGSTHRRDRQAFSMYEPGSALKPFGGTPGDELATRLQPFHSTELEDDAIYSVHVPAGLYRIRKGVSASSVPFTPSSPLLSCSQEGSR-HASKLSRHGSGADSDYENTQSGDPLLGLEGKRFLELSKEDELHPELESLDGDLDPGLPSTEDVILKTEQVTKNIQELLRAAQEFKHDSFVPCSEKIHLAVTEMASLFPKRPALEPVRSSLRLLNASAYRLQSECRKTVPPEPGAP-VDFQLLTQQVIQCAYDIAKAAKQLVTITTREKKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IPR8-1", "uniprot_id": "A0A0R4IPR8_DANRE", "id": "A0A0R4IPR8-1", "name": "", "aln": "MSRKVQRSEVCADCSAPDPGWSSINRGVLICDECCSVHRSLGRHISIVKHLRHSGWPPSLLQMVQTLASNGANSIWEHSLLDPAQVQSGRRKPNPQDKVHPTKSEFIRAKYQMLAFVHKLPCRDDDGVTTKDLSKQLHSSVRTGSLETCLRLLSLGAQANFFHPEKGTTPLHVAAKAGQVLQAELLVVYGADPGAPDINGRTPIDYARQAGHVELAERLVECQYELTDRLAFYLCGRRPDHKNGHYIIPQMADRARPKCPTQSLDLSELAKAAKKKLQALNNRLFEELAMDVYDEVDRRENDAVWLTTQNHSTLVTERSAVPFLPVNPEYSATRNQGRQKLARFNAREFATLIIDILSDAKRRQHGKGLTSPTDPLDLSQVD----DDQHDYDSVASDEDTDSELTAQNNNNTQRNNRAKSMDSSDLSDGPITLQEYLEVKKALASSEAKVQQLMKVNNNLSEELRRLQKEISRMQTENSALRGAQAGSGATMTGGGVPGHWPDRVRGMGGGGGLSGDSSLIAPSSTPHRRDRQAFSMYEPVGTTSKVLSPALDPLTCRLQPLSP-------------------VRKGAPAGPTPYG--GAHLSASTDGRYNHPKAGEKYGSGTDSDYDNSQTYDVSIGVGR------SSEEDSRGDVDDTEGDPDPTLPCTEDVILKTEQVTKNIQELLRAAQEFKHDSFVPCSEKIHLAVTEMASLFPKRPALDAVRSSLKLLAASASRLQVECRKAAPSDSSASTVDYQLLTQQVIQCAYDIAKAAKQLVTITTREKKQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** *:*************:**.****:************************.***:*****:***************************.******** ***************************:**************.**********************************.**************:**:************** ************************:*************** ******************.*************************:***************************************************:*****:**.*:**** *:** . ****************.* . . : *.***:**********.:*******:*****:************..**:******:** ::*:** ** . * ** * .: : :.*..:.************* .: . . ... * *: ****: . :***..*...*: .. **.* :* *.. .::***:****:*:*: * :*: ..*:: : :::. :** ** **.******************************************************:.*****:** *** *** ****:.*.:..*. **:*******************************", "identical_positions": 572, "similar_positions": 103, "identity": "72.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100409-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q02013-1", "uniprot_id": "AQP1_MOUSE", "id": "Q02013-1", "name": "Aquaporin-1", "aln": "--------------------------------------MASEIKKKLFWRAVVAEFLAMTLFVFISIGSALGFNYPLERNQTLVQDN----VKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISILRAVMYIIAQCVGAIVATAILSGITSSLVDNSLG----RNDLAHGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVLTRNFSN-HWIFWVGPFIGGALAVLIYDFILAPRSSDFTDRMKVWTSGQVEEYDLDADDINSRVEMKPK------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29975-1", "uniprot_id": "AQP1_RAT", "id": "P29975-1", "name": "Aquaporin-1", "aln": "--------------------------------------MASEIKKKLFWRAVVAEFLAMTLFVFISIGSALGFNYPLERNQTLVQDN----VKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISILRAVMYIIAQCVGAIVASAILSGITSSLLENSLG----RNDLARGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVLTRNFSN-HWIFWVGPFIGSALAVLIYDFILAPRSSDFTDRMKVWTSGQVEEYDLDADDINSRVEMKPK------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29972-1", "uniprot_id": "AQP1_HUMAN", "id": "P29972-1", "name": "Aquaporin-1", "aln": "--------------------------------------MASEFKKKLFWRAVVAEFLATTLFVFISIGSALGFKYPVGNNQTAVQDN----VKVSLAFGLSIATLAQSVGHISGAHLNPAVTLGLLLSCQISIFRALMYIIAQCVGAIVATAILSGITSSLTGNSLG----RNDLADGVNSGQGLGIEIIGTLQLVLCVLATTDRRRRDLGGSAPLAIGLSVALGHLLAIDYTGCGINPARSFGSAVITHNFSN-HWIFWVGPFIGGALAVLIYDFILAPRSSDLTDRVKVWTSGQVEEYDLDADDINSRVEMKPK------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQ72-1", "uniprot_id": "A0A8M3AQ72_DANRE", "id": "A0A8M3AQ72-1", "name": "", "aln": "--------------------------------------MARELKSWSFWRAVLAEFVGMTIFVFIGIASAIGNKH----NRYPDQE-----VKVALAFGLAIATLAQSLGHISGAHLNPAITLGLLVSCQISFFRAFMYIIAQMLGAVLASGIMFKVSPDP-DTTLG----LNMLGNGVKVGQGFAIELFATFQLVLCVLATTDKNRTDVSGSAPLAIGLSVGLGHLVAISYTGCGINPARSFGPAVVLESFKN-HWIYWIAPMCGGVAAALIYDFLLFPKREALRKRMNVLKGTADPDPSATEALIEPRSARSGSGVAGAE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V5Z7-1", "uniprot_id": "AQP_DROME", "id": "Q9V5Z7-1", "name": "Aquaporin", "aln": "--------------------------MVEKTEMSKFVGVADITENKKIWRMLLGELVGTFFLIFVGVGSTTSGSVP----------------QIAFTFGLTVATIAQGLGHLSGCHINPAVTLGFLIVGEISILKAAFYIIVQCVGAIAGAAVIKVALDGVAGGDLG----VSSFDPSLNCAQAVLIEALITFILVFVVKAVSDPGRQDIKGSAPLAVGLAIAAGHLCAIKLSGASMNPARSFGPAVVQGVWTY-HWVYWVGPIAGGLLAGIIYRLIFKVRKG----------DDETDSYDF--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0CD91-1", "uniprot_id": "AQY1_YEAST", "id": "P0CD91-1", "name": "Aquaporin-1", "aln": "MSSNDSNDTDKQHTRLDPTGVDDAYIPPEQPETKHHRFKISRDTLRDHFIAAVGEFCGTFMFLWCAYVICNVANHDVALVAAPDGSHPGQLIMIAIGFGFSVMFSIWCFAGVSGGALNPAMSLSLCLARAVSPTRCVVMWVSQIVAGMAAGGAASAMTP---GEVLF----ANSLGLGCSRTRGLFLEMFGTAILCLTVLMTAVEKR-ETNFMAALPIGISLFIAHVALTAYTGTGVNPARSLGAAVAARYFPHYHWIYWIGTLLGSILAWSVWQLLQILDYTTYVTAEKAASTKEKAQKKGETSSSSAVAEV---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9W1M4-1", "uniprot_id": "Q9W1M4_DROME", "id": "Q9W1M4-1", "name": "", "aln": "-----------------------------------------MIWDFFTFIRGATEFSATALLILLGCMGDSTNQGGES-----------KFLVASVHYGLTVMVVMHVFGFVSGAHSNPCISISCYLMGYIALEVMMMYVVCQMAGAFLGYFLLMQLLPKELVDKSKPGICLVQPMDTLSTYQVVIIECLLTAVLVLGWCSLWDVRNGRFLDSVAIRMGLLVIACSFAGIQLTGASMNPAKTLVPAIFYGSPNS-VLMQLTGQILAAIMVPFVWNHAYTPPYKPLEIPVCN-------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: . ::: . . :. :*::: .. :** **.:::. : :: . : * ... . . : . :* : * * : . ..: :*: : . :* .:***::: .*: : . : .. . :: ", "identical_positions": 16, "similar_positions": 61, "identity": "4.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100412-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q76L83-1", "uniprot_id": "ASXL2_HUMAN", "id": "Q76L83-1", "name": "Putative Polycomb group protein ASXL2", "aln": "MREKGRRKKGRTWAEAAKTVLEKYPNTPMSHKEILQVIQREGLKEIRSGTSPLACLNAMLHTNSRGEEGIFYKVPGRMGVYTLKKDVPDGVKELSEGSEESSDGQSDSQSSENSSSSSDGGSNKEGKKSRWKRKVSS------SSPQSGCPSPTIPAGKVISPSQKHSKKALKQALKQQQQKKQQQQCRPSISISSNQHLSLKTVKAASDSVPAKPATWEGKQSDGQTGSPQNSNSSFSSSVKVENTLLGLGKKSFQRSERLHTRQMKRTKCADIDVETPDSILVNTNLRALINKHTFSVLPGDCQQRLLLLLPEVDRQVGPDGLMKLNGSALNNEFFTSAAQGWKERLSEGEFTPEMQVRIRQEIEKEKKVEPWKEQFFESYYGQSSGLSLEDSKKLTASPSDPKVKKTPAEQPKSMPVSEASLIRIVPVVSQSECKEEALQMSSPGRKEECESQGEVQPNFSTSSEPLLSSALNTHELSSILPIKCPKDEDLLEQKPVTSAEQESEK-NHLTTASNYNKSESQESLVTSPSKPKSPGVEKPIVKPTAGAGPQETNMKEPLATLVDQSPESLKRKSSLTQEEAPVSWEKRPRVTENRQHQQPFQVSPQPFLNRGDRIQVRKVPPLKIPVSRISPMPFHPSQVSPRARFPVS--ITSPNRTGARTLADIKAKAQLVKAQRAAAAAAAAAAAAASVGGTIPGPGPGGGQGPGEGGEGQTARGGSPGSDRVSETGKGPTLELAGTGSRGGTRELLPCGPETQPQSETKTTPSQAQPHSVSGAQLQQTPPVPPTPAVSGACTSVPSPAHIEKLDNEKLNPTRATATVASVSHPQGPSSCRQEKAPSPTGPALISGASPVHCAADGTVELKAGPSKNIPNPSASSKTDASVPVAVTPSPLTSLLTTATLEKLPVPQVSATTAPAGSAPPSSTLPAASSLKTPGTSLNMNGPTLRPTSSIPANNPLVTQLLQGKDVPMEQILPKPLTKVEMKTVPLTAKEERGMGALIATNTTENSTREEVNERQSHPATQQQLGKTLQSKQLPQVPRPLQLFSAKELRDSSIDTHQYHEGLSKATQDQILQTLIQRVRRQNLLSVVPPSQFNFAHSGFQLEDISTSQRFMLGFAGR-RTSKPAMAGHYLLNISTYGRGSESFRRTHSVNPEDRFCLSSPTEALKMGYTDCKNATGESSSSKEDDTDEESTGDEQESVTVKEEPQVSQSAGKGDTSSGPHSRETLSTSDCLASK--NVKAEIPLNEQTTLSKENYLFTRGQTFDEKTLARDLIQAAQKQMAHAVRGKAIRSSPELFSSTVLPLPADSPTHQPLLLPPLQTPKLYGSPTQIGPSYRGMINVSTSSDMDHNSAVPGSQVSSNVGDVMSFSVTVTTIPASQAMNPSSHGQTIPVQAFSEENSIEGTPSKCYCRLKAMIMCKGCGAFCHDDCIGPSKLCVSCLVVR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BZ32-1", "uniprot_id": "ASXL2_MOUSE", "id": "Q8BZ32-1", "name": "Putative Polycomb group protein ASXL2", "aln": "MREKGRRKKGRTWAEAAKTVLEKYPNTPMSHKEILQVIQREGLKEIRSGTSPLACLNAMLHTNSRGEEGIFYKVPGRMGVYTLKKDVPDGVKELSECSEESSDGQSDSHSSDNSSSS-DGGSNKEGRKSRWKRKVSSRL-SHPPSPPSGCPSPTIPASKVISPSQKHSKKALKQALKQQQQKKKQQQCRPSMSIS-NQHLSLKTVKAASDSVPAKPG------------------------------------------------QMKRTKCADIDVETPDSILVNTNLRALINKHTFSVLPGDCQQRLLLLLPEVDRQVGPDGLMKLNGSALNNEFFTSAAQGWKERLSEGEFTPEMQVRIRQEIEKEKKVELWKEQFFENYYGQSSGLSLEDSQKLTASSSDPKAKKTPAEQPKSILPSEASPVRIVPVVPQSECKEEAVQIPSPSQKE--ENQDEARPD-SKSPEPVLASASNTNELITMKPIKSPKDEGLLEQKPVACAEQESEKENHVTTTSRNNKSENQEALAISPSKSKNAGLQKPIIKPVAEASPLNPDMKMPPATVTDQIQESLKRKSSLTDEEATSSWEKRPRITENRQHQQPFQVSPQPFLNRGDRVQVRKVPPLKIPVSRISPMLFSTSQVSPRARFPIS--ITSPYRTGARTLADIKAKAQLVEAQKAAAAAAAAAAAAASVGGTIPGPGPGGGQSPREGGERKIAGGGSAGSDPVSTNGKGPTLELAGTGSRGGTRELLPCGPQPETN-----MPGQAQPPGISGAQLQQTSSVPTGLASSGACTSVPLPAHIEISNSEKPNLHKATATAASPCHLQDPRSCRLEKALSPTGPPLISGASTVYFVADGTVEPKAGSNKNAPKPSALAKTTAPAPLDMTSSPVT----TASLEKLPVPQISGTATSTGSAPSSSTLPAASSLKTPGTSANMNGPISRTSSSIPANNPLVTQLLQGKDVPLEQILPKPLTKIEMKTVPLTTKEEKGIGIFPGISVMESSSREEVNGRQAHLAIP-QLGKPLQSKQLSQVPRP--VFTAKDRKDPCIDTHQYREGLSKTTQDQLFQTLIQRAQRQSVLSFVPPSQFNFAHSGFHLEDISTSQKFMLGFAGR-RTSKPAMAGHYLLNISTYGRGTENIKRTHSVNPDDRFCLSSPTEALRMGHADYKNTTGEISS-KEDESDEDRVGDEQEPISVKEEPWASQSSGR-----HPHHGEASSTNDCLASK--NGKTEAPVSEQTTLGQENYIFSRGQASDEKSLPRDFIPAAHKQMTHAVRGKTVCSSPELFNSTALSLPADSPTHQPLLLPPLQTPKLYGSPTQIGPSYRGMINVSTSSDMDHNSAIPGSQVSSNVGDVMSFSVTVTTIPASQAMNPSSHGQTIPVQTFPDDNSIEDTPSKCYCRLKAMIMCKGCGAFCHDDCIGPSKLCVSCLVVR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FG88-1", "uniprot_id": "E7FG88_DANRE", "id": "E7FG88-1", "name": "", "aln": "MRERQKKKKGRTWAEAAKTVLEKYPNTPMSHKEILQVIQRERLKEIS-GTSPLACLNAMLHTNSRGDEGIFYKVPGRMGVYTLKKDIGDGVKELSEDASDDSSDMSDSRCTENTSST---GYSKDGRRRRWTRRVPTKLQSQPSSPQSRCSSPSVSSSKLMSPSQKHSKKALKQALKQQQQRNQRRQCG--ISNASSPRLLLKTVKDMAHDS-SKSS-WELKKSERCPASPHNSTSSSSSSVKADVCHTSSARKVSQRSSRLNARQLRRSRC-EIDVETPDSILVNTNLRALINKHTFSLLPTDCQQKLLKMLPEVDQQASMDGALKVTSSALNNEFFTSAAQSWKERLSEGEFTPELRLRMRQEIEKEKKVDLWKEQFFESYYGEHSGLCIEESKELTEAKELPEPAKKAVVPVKPEIVIEPRKVNPVIEVIHMELRSRDVKSTVMHTSP------EEPVKLPASEKSRLSLDTKKDVLVELIPVSS--TQKMVDPKPDSEKTLESEIRCKTPTSP-------LEAMVTCLKRKETHSTKE--ESPVSGAGQALTERNKGGSTATAVTSEPLKRKIS-SEQDAEVITEKKPRSSS--PEESPTVTAKEKLEQR--------VPPLKIPVSRILSAPASIEQISPRTPVPLTPPSVRPGRTGARTLADIKAKAQLARAQRAAAAAARSSSSK-------------------------------------------------GTGSVGGTSTPSPARSLSEDFS-----PASSKSQSVSPIKLSSGSPAPEG-------TVTLSQTFPSSGSAGYTDPVFAQAFSASQGFLKENRSS--------------FGLQTTQCSLN---------------PIGKDQHYLLCP-------------------------EGTLAPSGQAGNVTVSNTIAQSQRPQQTLFAGASAAKLISSIPENNPLVTQLLQGKEVPLEKILPKPLTNAEVQSVAISARDKGNLDTTTAGWKKDSPTIQEVS------------------KFVNQVPFD----------QPAKQVSSRDKFVKVGTQDRILQPLREQKHTS---SNRQSSQFHSCHLGHP--ESSQDQSVHLGIFGRKRISKPAMTGHYLLNVSTYGRGSESSKRPHQAS---------------------NTSTTLANLKKEKIEAEDSVKGTTESLAG------TTSQGH-----APFPSVKVEQQGCFISKPDDGLAPQPCTDVKSESPSLSCLSSKEEGSSSTRTKETCSKGQLDMCSTIQGKTEP-------------YQLSDCHQRMFLP----QKAHNG-TQYGGSISMSVPHALNHSMPDTPSCSGDGETAG-GGMMSFSVTVTTIPAGHLLDQSSQRETSPEEAFIETSGMEDVQSKCYCRLKAMIMCKGCGAFCHDDCIGPSKLCVSCLVVR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***: ::********************************** **** ******************:*******************: ******** :.:.*.. ***:.::*:**: * .*:*:: **.*:*.: .** * *.**::.:.*::********************:::::** :* : . :* ***** :.. :*.. *::*::* :*************************:** ****:** :*****:*.. ** :*:..*************.*************:::*:**********: *******.***: ***.:*:*::** : . *: *... *. *. :. * * : * :.. :: . . * . . * :. *: :.. * : *:.. : ::: ** : *** : .*:. *::. . .: :. . :: .*.: *. .: : :* . *.**** * ::::* **:** :. .:.* .: : : :* *********** . .*:***: .*:: . * ****************..**:****** :::: **** *** *. . .: *..::. .:* :*.. ...* * . :. . . : * * ** . : *. * ... : * . : * ..* :.:*.* :. : :. : * : ... : **** ************:**:*:*******: *:::*.:::::: .:. . :..: :**. * : *** :.. :. . : :. ***:::*.* :: : . * .***: .* *. : * .* . **: ** * *****:******:******:*. :*.*... :.:* . **. *: . . *.:: : * *: *. . ..*: ** : : * .: .: . . :: : ...: .:: .: :* :::**: * ** ::** * :.. ** * * : : . .* ...: .*. ::. *.:************.: :: **: :* * ::* : ..:*.. **************************************", "identical_positions": 493, "similar_positions": 352, "identity": "34.07%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100414-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P25025-1", "uniprot_id": "CXCR2_HUMAN", "id": "P25025-1", "name": "C-X-C chemokine receptor type 2", "aln": "MEDFNMESDSFEDFWKGEDLSNYSYSSTLPPFLLDAAPCEPESLEINKYFVVIIYALVFLLSLLGNSLVMLVILYSRVGRSVTDVYLLNLALADLLFALTLPIWAASKVNG-WIFGTFLCKVVSLLKEVNFYSGILLLACISVDRYLAIVHATRTLTQKRYLVKFICLSIWGLSLLLALPVLLFRRTVYSSNVSPACYEDMGNN-TANWRMLLRILPQSFGFIVPLLIMLFCYGFTLRTLFKAHMGQKHRAMRVIFAVVLIFLLCWLPYNLVLLADTLMRTQVIQETCERRNHIDRALDATEILGILHSCLNPLIYAFIGQKFRHGLLKILAIHGLISKDSLPKDSRPSFVGS-SSGHTSTTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q8T9-1", "uniprot_id": "F1Q8T9_DANRE", "id": "F1Q8T9-1", "name": "C-X-C chemokine receptor type 2", "aln": "-----MET-----------------ATTEFPFTL-MTPCPETVKNLNSTVLVVIYIIVFCLSLLGNTVVIFVVFFMDNRRTSTDLYLMHLAVADLLFSLTLPFWVAYLHAGHWPFGTIMCKMISGVQEVTFYCSVFMLACISIDRYMAIVKATQFLNRKLHLIGFVCALVWLCAALLSLPVMVHREAITYDGVEYICEDNVTAESTDSWRMSLRIIRHTLGFFLPLTVMMFCYGFTMFTLCHTRNSQKQKAMRVILSVVLAFIICWLPHNIIEFTDILMRAGQVEETCQLRDNIDVALYATQVMAFAHCAINPILYAFIGKKFRNQLLISLFKKGLFGRNMLSRYGAGSFQSSGSTRQMSVTL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: ::* ** * :** ::*. .:*:** :** ******::*::*::: *: **:**::**:*****:****:*.* * * ***::**::* ::**.**..:::*****:***:***:**: *.:* :*: *:* :* : **:***::.*.:: ..*. * ::: : * .*** ***: :::**::** :*:******: ** ::: .**::*****::*** *::****:*:: ::* ***: ::***: *::** ** **:::.: *..:**::*****:***: ** * :**:.:: *.: . ** .* *: : *.**", "identical_positions": 153, "similar_positions": 118, "identity": "42.15%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100415-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVR2-1", "uniprot_id": "TYPH_RAT", "id": "Q5FVR2-1", "name": "Thymidine phosphorylase", "aln": "MAAPGTPPPLAPETAGADSGGGSG-------EHRQLPELIRLKRNGGHLSEADIRNFVHALMDGRAQDTQIGAMLMAIRLQGMDLEETSVLTQALAESGQQLEWPKAWHQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRSLGHTGGTLDKLESIPGFSVTQSPEQMLQILEEVGCCIVGQSEKLVPADGILYAARDVTATVDSVPLITASILSKKAVEGLSTLVVDVKFGGAAVFPDQEKARELAKMLVRVGMGLGLQVAAALTAMDNPLGRNVGHTLEVEEALLCLDGAGPPDLRDLVIRLGGAILWLSGQAETQDQGAARVAAALDDGSALHRFQLMLSAQGVDPGLARALCSGSPTQRRQLLPHARKQEELLSPADGIVECVRALPLACVLHELGAGRSRAGQPIRPGVGAELLVDVGQWLSRGTPWLRVHLDGPALSSQQRRTLLGALVLSDRAPFKAPSPFAELVLPPTTP--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99N42-1", "uniprot_id": "TYPH_MOUSE", "id": "Q99N42-1", "name": "Thymidine phosphorylase", "aln": "MAAPGTPPPSA-------SGGGGG-------EPRQLPELIRLKRDGGHLREADIRNFVHAVIDGRAQDTQIGAMLMAIRLQGMNLEETSVLTRALAESGQQLEWPKAWHQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRSLGHTGGTLDKLESIPGFGVTQSPEQMLHILEEVGCCIVGQSAKLVPADGILYAARDVTATVDSVPLITASILSKKAVEGLSTLVVDVKFGGAAVFPDQEKARELAKMLVRVGVSLGLKVAAALTAMDNPLGRSVGHTLEVEEALLCLDGAGPPDLRDLVIRLGGAILWISGQAETQDQGAARVAAALDDGSARRRFQLMLSAQGVDPGLAKALCSGSPTQRRQLLPHAREQEELLAPADGIVECVRALPLARVLHDLGAGRSRAGQPIRPGVGAEVLVDVGQCLSRGTPWLRVHLDGPALSSQQRRTLQGALVLSDRAPFKVPSPFAELVLPPTIAQP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P19971-1", "uniprot_id": "TYPH_HUMAN", "id": "P19971-1", "name": "Thymidine phosphorylase", "aln": "MAALMTPGTGAPPAPGDFSGEGSQGLPDPSPEPKQLPELIRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETSVLTQALAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVLAPALAACGCKVPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSEQLVPADGILYAARDVTATVDSLPLITASILSKKLVEGLSALVVDVKFGGAAVFPNQEQARELAKTLVGVGASLGLRVAAALTAMDKPLGRCVGHALEVEEALLCMDGAGPPDLRDLVTTLGGALLWLSGHAGTQAQGAARVAAALDDGSALGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADGTVELVRALPLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLRVHRDGPALSGPQSRALQEALVLSDRAPFAAPSPFAELVLPPQQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B8W2-1", "uniprot_id": "A0A8M3B8W2_DANRE", "id": "A0A8M3B8W2-1", "name": "Thymidine phosphorylase", "aln": "MSSED--------------------------DTISFPELIKLKRNGGQLSLAEIHTFVQGVTTGAIQKSQIGAMLMAIWQKGMTDEETLALTREMMNSGDTFKWPNEW--LVLDKHSTGGVGDKVSLPLAPALAACGCKVPMISGRGLAHTGGTLDKLESIPGFNVNQSVQQVKQILEDVGCCIVGQTESLVPADRVLYAIRDATSTVDSLPLITSSIISKKGAEGLSALVLDVKFGRAALYKDLDRARSLAQCLVTAGNELGIKTGAVLSRMDAPIGQTVGNAVEVCEALECLKGRGPDDLRELVTNLGGHLLWMCGHSSTLENGKHEIAVKLKNGEALNKFQAMLEAQGVTADVARSLCSDE-SRYFEYMKRAANQTELKVPKDGAVLDIDGLALAEVLHKLGAGRTKSGEKIDHSVGAEMLVEMGQLVQKGQTWIRIHHSSVDLSAQQRSDLQKALVIGRQDQYKAASRIVEFIYPNHHMS-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: : .:****::**:**:* *:*: ** .: * * :********* :** *** .**: : :**: ::**: * ::************** ******************.*.***************.* ** :*: :*::.*******: .***** :*** **.*:****:****:**:*** .****:**:***** **:: : ::**.**: ** .* **::..*.*: ** *:*: **:::** *** *:.* ** ***:** *** :**:.*:: * :* .:*. *.:*.* :*: ** **** ..:*::***.. :. : : :* :* ** * ** * : .*.** ***.*****:::*: : .****:**::** : :* .*:*:* .. **. * * ***:. : : ..* :.*:: * ", "identical_positions": 230, "similar_positions": 125, "identity": "47.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100419-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O75356-1", "uniprot_id": "ENTP5_HUMAN", "id": "O75356-1", "name": "Nucleoside diphosphate phosphatase ENTPD5", "aln": "---------MATSWGTVFFMLVVSCVCSAVSHR------------NQQTWFEGIFLSSMCPINVSAS-TLYGIMFDAGSTGTRIHVYTFVQKMPGQLPILEGEVFDSVKPGLSAFVDQPKQGAETVQGLLEVAKDSIPRSHWKKTPVVLKATAGLRLLPEHKAKALLFEVKEIFRKSPFLVPKGSVSIMDGSDEGILAWVTVNFLTGQLHGHRQETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTYKLYTHSYLGFGLKAARLATLGALETEGTDGHTFRSACLPRWLEAEWIFGGVKYQYGGNQEGEVGFEPCYAEVLRVVRGKLHQPEEVQRG-SFYAFSYYYDRAVDTDMIDYEKGGILKVEDFERKAREVCDNLENFTSGSPFLCMDLSYITALLKDGFGFADSTVLQLTKKVNNIETGWALGATFHLLQSLGISH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WUZ9-1", "uniprot_id": "ENTP5_MOUSE", "id": "Q9WUZ9-1", "name": "Ectonucleoside triphosphate diphosphohydrolase 5", "aln": "---------MATSWG-AVFMLIIACVGSTVFYR------------EQQTWFEGVFLSSMCPINVSAG-TFYGIMFDAGSTGTRIHVYTFVQKTAGQLPFLEGEIFDSVKPGLSAFVDQPKQGAETVQELLEVAKDSIPRSHWERTPVVLKATAGLRLLPEQKAQALLLEVEEIFKNSPFLVPDGSVSIMDGSYEGILAWVTVNFLTGQLHGRGQETVGTLDLGGASTQITFLPQFEKTLEQTPRGYLTSFEMFNSTFKLYTHSYLGFGLKAARLATLGALEAKGTDGHTFRSACLPRWLEAEWIFGGVKYQYGGNQEGEMGFEPCYAEVLRVVQGKLHQPEEVRGS-AFYAFSYYYDRAADTHLIDYEKGGVLKVEDFERKAREVCDNLGSFSSGSPFLCMDLTYITALLKDGFGFADGTLLQLTKKVNNIETGWALGATFHLLQSLGITS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F8A7-1", "uniprot_id": "E7F8A7_DANRE", "id": "E7F8A7-1", "name": "nucleoside diphosphate phosphatase", "aln": "MSQQMLHLTLVSMWLFAGYFLAEATYYNHHMYNRYRAINHNANMDNQLPPEEPVVMEPVAPRQVNFSRVFYGIMFDAGSSGTRIHIYKFIQKDPVELPVLDNEMYHAVKPGLSAYADMPEKGGESIVQLLKVAKKTIPKEQWIQTPVVLKATAGLRLLPEEKAKALLNEVKEVFDDSPFFVPNNSVTIMNGINEGVLAWVTVNFLTGHLYSKTKRTVGILDLGGGSTQITFLPRLKKTVQSAPSDYIAKINMFNSTYELYTHSYLGNGVFASRLATLGALGADGLEWKVFRSSCLPKKFSEEWSFGGLTYKVSGTPDGYAGYKLCYQEVLQVVKGIVHQPFEVKGSSIFYAFSYYYDRAVESGLIDGSRGGTVEVRDFKKKAKEVCNKMTKYRPISPYLCMDMTYITCLLKDGFGFKDSTVLQLAKKVNNVETSWALGAIFDHFHNFSIQ-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: * . ::* : . :. :* . * :.:..:.* :*. . .:*********:*****:*.*:** . :**.*:.*::.:*******:.* *::*.*:: **:***.:**:.:* :****************.**:*** **:*:* .***:**..**:**:* **:***********:*:.: :.*** *****.********:::**::.:* .*::.::*****::******** *: *:******** :.* : :.***:***: :. ** ***:.*: .*. :* *:: ** ***:**:* :*** **: . ***********.:: :** .:** ::*.**::**:***::: .: . **:****::***.******** *.*:***:*****:**.***** *. ::.:.* ", "identical_positions": 227, "similar_positions": 141, "identity": "50.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100419-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZTX2-1", "uniprot_id": "A0A8I5ZTX2_RAT", "id": "A0A8I5ZTX2-1", "name": "", "aln": "---MDVTVSQLVELFLQSPLVTWVKTFGPFGSGHQDNLTLYMDLVDGIFLNQIMLQIDPRPSNQRINKHVNNDVNLRIQ---NLSILVRNIKTYYQEVLQQLIVMNLPNVLMIGKDPLSGKSMEEIKKVLLLVLGCAVQCERKEEFIERIKQLDIETQAGIVAHIQEVTHNQENVFDLQWLDLPDVAPEELEALSRNMVFHLRRLIDERDECTELIVDLTQERDYLQAQHPPSPGKFSSPD-STPSPTSSLSSEDKQHLAVELADTKARLRRVRQELEEKTEQLADTRHEVDQLVLELQKAKQDNIQLAADARSARAYRDELDSLREKANRVERLEMELVRCKEKLHDVDFYKARMEELREDNIILIETKAMLEEQLTASRARSDKVHELEKENLQLKSKLHDLELDRDTDKKRIEELLEENMVLEIAQKQSMNESAHLGWELEQLSKNADLSDASRKSFVFELNECASSRILKLEKENQSLQSTIQGLRDASLALEESSLKCGELEKENQQLSKKAGSLYLQIEKLQTQLEREKQSNQDLETLSEELIREKEQLQSGMEALKADRARQIKDLEQEKGHLHQAVWSLRERPQVN---SMKDVEKENRTLHQAVTEAGSKLSQLESEKKQLHRDLEEAKEKGERAEVLEKELHRLEKENEQLTKKVTSLKTVTEKVEALEHESQGLELENRTLRKSLDTLQNVSVQLEGLERDNKQLDQENRELRKMVEAMRFTSAKMAQMETENQQLEREKEELRRNVEMLKTLSKKSERLEHSYQSVSAENLQLQHSLESSNHKSQALQRELSELEAERQALKRDLETLQLANKQLEGAEKDRKALEQEVAQLEKDKKLLEKETRRLWQQVELKDAVLDDSAAKLSAAEKESRALDKELARCRDAASKLKELEKDNRDLTKQVTVHTRTLTTLREDLVLEKLKSQQLTSELDKLSQELEKVGLSKELLLQEDNSHGDTKGKIWESKNESSLKTTLAMKEEKIVFLEAQVEEKESLNHQLQIELQMVKKECEQLRKTQEDGTQAQNVQKHAPDK-VTSHQEKEAWGPSHKEATMELLRVKDRAIELER--------------------------SNAALQAERQLLKEQLQHLETQNVSFSSQILTLQKQSAFLQEHTTTLQTQTAKLQVENSTLSSQNAALSAQYTMLQSQHAAKEAEHESLQQQQEELAAVYEALLRDHDRLGALYERQSSEYEALICQHSCLKTLHRNLELEHKELGERHGDLQKRKAELEELEKALSTEREVLQQEQRTSAIATSENQRLRGELDRISFLHHQLKGEYEELHAHTKELKTSLNNSRLELNRWQARFDELKEQHQNMDISLTKLDNHCELLSRLKGNLEEENQHLLSQIQLLSQQNQMLLEQNIESKEQYHEEQKQYIDKLNALRRHKEKLEEKIMDQYKFYDPAPKKKNHWIGAKALVKLIKPKKEGSRER-------LKSS-DSPPWQLES----SDPASPPASQTLRPQTENSDNPPSGSN---CTEE---------RDTHNGPVGKGPGDLKPKRGSPRGGTVDRTDTSTDPAVKSWPSEPGSRSFSTSATTAALSS----STPILKHLGRTKGCNSDDNLCEPSPEP--EGPYHRQQVSRPNSLESSRSTSSNSSPLSLKGSSDHLHSRCESFSSADLIPSRDPTTLSRDGSTPGRGLLGRHEYPPPRNGPVPQENIQKKGAASAHTGVRPHSASPSSEMVTLEEFLEESNRG-SPTHDTPSCRDDLLSDYFRKAHDPPAMGGQPGPPTRKEGAKMPTSFVAPTVKMPVSTSEGQQLKPGHYVKPNLRPSEAEALAGIPSRQVQPPQSLSLGRPRQATMSQTCHVPVSRSASLSRAFSLASADLLRASGPEACRPESPQKPGCPEAVGTRETSGHSLQG-----SHILPRERTPIVGKADSSSPGPGTRGRP-LDTRRFSLAPPKEER--LAPLQQSATAPALATG------CGSGSNPQIQHFSPTVAPAVRTKPKGPQHSGEVATVAPVRPGLGTSEGDGGPGHGYSEGLLTKSPGRSSDLAPHVKRGPDDFSQGSSSKSTPASPEPGGDPQTVWYEYGCV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6VGS5-1", "uniprot_id": "DAPLE_MOUSE", "id": "Q6VGS5-1", "name": "Protein Daple", "aln": "---MDVTVSQLVELFLQSPLVTWVKTFGSFGSGHQDNLTLYMDLVDGIFLNQIMLQIDPRPSNQRINKHVNNDVNLRIQ---NLSILVRNIKTYYQEVLQQLIVMNLPNVLMIGKDPLSGKSMEEIKKVLLLVLGCAVQCERKEEFIERIKQLDIETQAGIVAHIQEVTHNQENVFDLQWLDLPDVAPEELEALSRNMVFHLRRLIDERDECTELIVDLTQERDYLQTQQPPSPGKFSSPD-STPSPTSSLSSEDKQHLAVELADTKARLRRVRQELEEKTEQLADTRHEVDQLVLELQKAKQDNIQLAADARSARAYRDELDSLREKANRVERLEMDLVRCKEKLHDVDFYKARMEELREDNIILIETKAMLEEQLTASRARSDKVHELEKENLQLKSKLHDLELDRDADKKQIEKLLEEYMVLEMAQKQSMKESAHLGWELEQLSKNADLSDASRKSFVFELNECASSRILKLEKENQSLQSTIQGLRDTSLALEESSLKYGELEKENQQLSKK-------IEKLQTQLEREKQSNQDLETLSEELIREKEQLQSGMEALKADRARQIKDLEQEKGHLHQAVWSLRERPQVN---STKDVEKENRALHQAVTEAGSKLSQLELEKQQLHRDLEEAKEKGEQAEALEKELHRLEKENEQLTKEVTSLKAATEKVEALEHQSQGLELENRSLRKSLDTLQNVSVQLEGLERDKQQLGQENLELRKMVEAMRFTSAKMAQIETENRQLEREKEELRRDVELLKTLSKKSERLELSYQSVSAENLQLQHSLESSTHKSQALQRELSQLEAERQALRRDLETLQLTHKQLEGAEEDRKALEQEVAQLEKDKKLLEKEARRLWQQVELKDAILDDSAAKLSAAEKESRALDKELARCRDVGSKLKELEKDNRDLTKQVTMHTRTLTTLREDLVLEKLKSQQLSSELDKLSQELEKVGLSKDLLLQEDDGHGDGKG-----KTESALKTTLAMKEEKIVFLEAQVEEKESLSRQLQIELQMIKKEHEQLRQTQEGGDKAQNALKRPPGK-VTSHQEKEAWEPSHKEATMELLRVKDRAIELER--------------------------SNAALQAERQLLKEQLQHLETQNVSFSSQILTLQKQSAFLQEHTTTLQTQTAKLQVENSTLSSQNAALSAQYTVLQSQQAAKEAEHEGLQQQQEQLAAVYEALLQDHKHLGTLYECQSSEYEALIRQHSCLKTLHRNLELEHKELGERHGDLQQRKAELEELEKVLSTEREALEREQKTNAIATSENQRLRGELDRISFLHQQLKGEYEELHAHTKELKTSLNNSQLELSRWQVRFDELKEQHQSMDISLTKMDNHCELLSRLKGNLEEENHHLLSQIQLLSQQNQMLLEQNMESKEQYHEEQKQYIDKLNALRRHKEKLEEKIMDQYKFYDPAPKKKNHWIGAKALVKLIKPKKEGSRER-------LKSTTDSPPWQLEP----SDPASPSPSQALRSQTENPDNPPSGPN---CVEE---------RDTHNGPVGKGPGDLKPKRGSPRGGSVDRTDTSTDPAVKSWPSEPGSRTFSTSATTAALSS----STPIPKHLGRTKGCNSDDNLCEPSSEP--DGPYHRQQASRPNSLESSRNASSNSSPLSLKGSSDHLHSRCESFSSADLIPSRDPATLSRDGNTSGRGLLGRHEYPPPRNGPVSQETIQKKGAASTHTGVRPHSASPSSEMVTLEEFLEESNRGGSPTHDTPSCRDDLLSDYFRKAHDPPALGGQPGPPARKDGAKMPTSFVAPTIKMSINTSEGQQLKPGHYVKPNLRPSEAEALAGMPSRQVQPPQSLSLGRPRQTTMTQNCHMPVSRSASLSRAFSLASADLLRASGPEACRPESPQKPGGHEAAGARETSTHSLQG-----SHILARERTPIVGKADSPSPGQGTRGRP-LDTRRFSLAPPKEER--LAPLQQSATAPALATG------CSSGSNPQIQHFSPTVAPAVRTKSKVPQHSGEVATVAPVRPGLGTSEGDGGPGHGYSEGLLTKSPGRSSDLPPHVKRGPDDFSQGSSSKSTPASPEPGGDPQTVWYEYGCV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P219-1", "uniprot_id": "DAPLE_HUMAN", "id": "Q9P219-1", "name": "Protein Daple", "aln": "---MDVTVSELLELFLQSPLVTWVKTFGPFGSGSQDNLTMYMDLVDGIFLNQIMLQIDPRPTNQRINKHVNNDVNLRIQ---NLTILVRNIKTYYQEVLQQLIVMNLPNVLMIGRDPLSGKSMEEIKKVLLLVLGCAVQCERKEEFIERIKQLDIETQAGIVAHIQEVTHNQENVFDLQWLELPDVAPEELEALSRSMVLHLRRLIDQRDECTELIVDLTQERDYLQAQHPPSPIKSSSAD-STPSPTSSLSSEDKQHLAVELADTKARLRRVRQELEDKTEQLVDTRHEVDQLVLELQKVKQENIQLAADARSARAYRDELDSLREKANRVERLELELTRCKEKLHDVDFYKARMEELREDNIILIETKAMLEEQLTAARARGDKVHELEKENLQLKSKLHDLELDRDTDKKRIEELLEENMVLEIAQKQSMNESAHLGWELEQLSKNADLSDASRKSFVFELNECASSRILKLEKENQSLQSTIQGLRDASLVLEESGLKCGELEKENHQLSKK-------IEKLQTQLEREKQSNQDLETLSEELIREKEQLQSDMETLKADKARQIKDLEQEKDHLNRAMWSLRERSQVSSEARMKDVEKENKALHQTVTEANGKLSQLEFEKRQLHRDLEQAKEKGERAEKLERELQRLQEENGRLARKVTSLETATEKVEALEHESQGLQLENRTLRKSLDTLQNVSLQLEGLERDNKQLDAENLELRRLVETMRFTSTKLAQMERENQQLEREKEELRKNVDLLKALGKKSERLELSYQSVSAENLRLQQSLESSSHKTQTLESELGELEAERQALRRDLEALRLANAQLEGAEKDRKALEQEVAQLEKDKKLLEKEAKRLWQQVELKDAVLDDSTAKLSAVEKESRALDKELARCRDAAGKLKELEKDNRDLTKQVTVHARTLTTLREDLVLEKLKSQQLSSELDKLSQELEKVGLNRELLLQEDDSGSDTKYKILEGRNESALKTTLAMKEEKIVLLEAQMEEKASLNRQLESELQMLKKECETLRQNQGEGQHLQNSFKHPAGKTAASHQGKEAWGPGHKEATMELLRVKDRAIELER--------------------------NNAALQAEKQLLKEQLQHLETQNVTFSSQILTLQKQSAFLQEHNTTLQTQTAKLQVENSTLSSQSAALTAQYTLLQNHHTAKETENESLQRQQEQLTAAYEALLQDHEHLGTLHERQSAEYEALIRQHSCLKTLHRNLELEHKELGERHGDMLKRKAELEEREKVLTTEREALQQEQRTNALAMGENQRLRGELDRVNFLHHQLKGEYEELHAHTKELKTSLNNAQLELNRWQARFDELKEQHQTMDISLTKLDNHCELLSRLKGNLEEENHHLLSQIQLLSQQNQMLLEQNMENKEQYHEEQKQYIDKLNALRRHKEKLEEKIMDQYKFYDPPPKKKNHWIGAKALVKLIKPKKEGSRER-------LKSTVDSPPWQLES----SDPASPAASQPLRSQAENPDTPALGSN---CAEE---------RDAHNGSVGKGPGDLKPKRGSPHRGSLDRTDASTDLAMRSWPSELGSRTCSTSATTTAPSN----STPIARHPGRTKGYNSDDNLCEPSLEF--EVPNHRQYVSRPSSLESSRNTSSNSSPLNLKGSSEQLHGRSESFSSEDLIPSRDLATLPREASTPGRNALGRHEYPLPRNGPLPQEGAQKRGTAPPYVGVRPCSASPSSEMVTLEEFLEESNRS-SPTHDTPSCRDDLLSDYFRKASDPPAIGGQPGPPAKKEGAKMPTNFVAPTVKMAAPTSEGRPLKPGQYVKPNFRLTEAEAPPSVAPRQAQPPQSLSLGRPRQAPVPPASHAPASRSASLSRAFSLASADLLRASGPEACKQESPQKLGAPEALGGRETGSHTLQSPAPPSSHSLARERTPLVGKAGSSCQGPGPRSRP-LDTRRFSLAPPKEER--LAPLHQSATAPAIATAGAGAAAAGSGSNSQLLHFSPAAAPAARTKPKAPPRSGEVATITPVRAGLSLSEGDGVPGQGCSEGLPAKSPGRSPDLAPHLGRALEDCSRGSVSKSSPASPEPGGDPQTVWYEYGCV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QCI3-1", "uniprot_id": "DAPLE_DANRE", "id": "A0A2R8QCI3-1", "name": "Protein Daple", "aln": "---MDITVSELMSNFMDSPLVVWVKTFGPLGFSSEDKLSMFMDLVDGVFLHKIMTHIDPSPMNQRVNKQVNNDVNLRIQ---NLNTVIRHIKNYYQEHLQQLIVMNLPNVLAIAKDPLSGKSMEEMKRMLLLILGCAVQCDRKEEIIEKIKLLDIETQAAIVTHIQEVTHNQENVLDLQWMEVAEIPAEQLDPLSRTMAFHLRKLIDERDESAELVIELTQERDYLQSQQPSGLLGFPSPERTSLSPITLLSKEDRQHLAVELADTKAKLRRSRQELEEKTEQLIDAKNEIERLDSDIQKLKQENTQLLAEARSVRAYRDEVDSLRERAGKVDRLETELSRFKEKLNDVHFYKTRIEELREDNLTLLETKSMLEEQLTGARGRCDKLHELEKENLQLRSKLHDIEIDRDSDKKRLEELLEENMLLEISQKQSMNESAHLGWELEQLAKNNEVNEA-RKSFVFELNESASSRLLKLEKENQCLQSTIQELREASINMEEGQLHSLELEKENQSLSKK-------LERLQSQLDQEKQTTQDMENLGEELIKEKQRMEKTLETIQAEKDRQISELEQEKEHLTQAVSSLRKRAQANSEARVREVETENRILHQTISETGGKLARLEAEKRQVTKELESLRERGERCEELEREVPRLERVREQLQREAAALKIGSERAEALERENATLEQDNRRLKKLADTAQNATLRLAVLEKDHQQLEEENLEQRRALETLRPAAARLAQLQQEHAELEREHEEMCRTMEELRSQAKRSERLEKSCGSLSLENQRLQQTLENSSTKMQGLESELRQNEAEMKDLQRELEGLRQKVTWAETLEKENRGMEQELSQLEKEKKQLEKEARRFRQQLEVKEAALEENCLRLASMEKEGTALSKELGRVKEAAGRLKELERENKDLQKQATMDKKTLATLREELVNEKLRVQQQCNELEKLSHELEKIGLNREKLLQEEHSCEDNKYKILETKIESALKKTLELREEKIQSLESRLEESSSLNQQLRTELTTVKKNLEALKQRHEEEAAHSEISQQTLGQ-TRSLPDKEKWEMEQREATAELLKLKDRLIDVEKNVRQRHVSIDIHRVIFSIVICFCDSLQNAALQTEKYLLKDQLKQIDSQNAQLNAQTLALQKQAASLQEHNTSLHKETAKLQVENSTLSSQSSSLMAQYGALQAQLQTLESEAESLQKQREEASAARDRVTQDHERLLGVHERQASEYEQLIAQHAALKASQRALEQENRTLENKYMVLLKQKDAMEALEESLQRDRESLGEEIRKNTLILGENRSLREEVDRVSHMHTQLRQEYDSLQLQTKELKTSLNESQLELNRWQARYDQLKEQHQGLDISMTKLDNHCELLTRLKGNLEEENHHLLSQIQMLSQQNQTLLERTMESKELYHEEQKQYIDKLNSLRRQKEKLEEKIMDQYKFYDPTPKKSRQWVGAKAIAKFIKPKKESSRERPDAPRERIRSAPDIPLPEIPTCIDCPESAPPPPPPPLPPRQSRPSLDSMNSQ---SVEENHVQSPTLSSPALNGRVLNESGGSRSRDGYRSIGGGSESMNGYEELLRWRSREPGGATCSTPLSRNSHNAPGFTSSSSLRPGRRPKGLVSEEDLRHHSPDAGFGSGVHGNTGHRPSSAEFSRNTSSSNSPVSSKGSLDCLQGRSASLSSDDVVG------LAHEGSRLSQSSLLPRSSTLPCDSPSASRPSQRPASR--------RPSSPGSEMVTLEEFLQESNALSPPTVQTGS-REDLMTDYFTRSTRPVPLR---------DGAKTPTNYVTPTVKTTPPELDARTPKPGHSVKPSVRLTDTSTPP----SHSQTLPNRGAGLRPSALQQSSPRGSVGGSASLSRTFSLASADLLRSNGPDSYRTEAAS-PNQNDVVMRR--------------PGAVARER-PMSARVTGSSPLPGDPGHISVDPRRLSLAQPRDEFSLVSPPPLHSSSMSLQAER---EYVGSGSS------RAGAARSGSAQPRGAPHRGEVAMVTPVRAVPALRLND-------LEEEPQEQREAESPLLKKADTTNLSYASKEQPTSKPASPDPNNDPQTVWYEYGCV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZT7-1", "uniprot_id": "Q9VZT7_DROME", "id": "Q9VZT7-1", "name": "", "aln": "MAGTATATPMEIDEFVNSSIISWLESCLPR----AELLAGYTSLLDGHIIHSVWLQIDPEPQNNPSELNDLNGKSLSIARAKNFECVVRNLKSFFEEELGQTILV-LPDAFTLGHHPESKNGLEQMKTLLTLLLGAAVQCPNKELFIARIKELDLETQHAIVGLIKQVTDSHSLVLTEDSLER--LTPQSMYTHILRLTKERDVMYLKWIDLACVETEMTASDNLVECGQGVSVTRSPSNG-TATSTPSSSSNSESNHLAVECADLRSKNRKLRQELEEKSENLLELREELDDKKARFDKLRQESQEWFTEAKRASAYRDEVDILRERAERADRLEVEVQKYREKLGDSDFYKSRVEELREDNRVLLESKEMLEEQLQRYRKRSEHAISLESEIIKYKQKINDMALERDVDRSKLEELLEENSQLQLVARN-LNSTMDL---DKSFSENEDDCNSGDNSLSEQLTNNAQTRALKLELENRRLTAALEQLKES--SFHESTSKMLELEKEKKKLSLK-------IEQMQENINRLTQQNVELEGVFKNALEENKKLQDAVDNRQKSYDRQSLEREADR---------------------------------------------------------QKLSDAEQHVETLNKEKQRIQTLNESIQRRADDLER------------------------------------------------------------------------------------------------------------------------------------------LAESKTKELEQYLEKSRQYELTKQKLYEIEARVSTYERENASLLKEVSKLKEGSEQKSVQLDDSINRLDVQSKELQKLGKALEDSEQVHQKLVELEKQNQELASQRIIDQEMISTLRNDLVTGTLVTKKVRNNLEKLGLADEEPGELNVEHVVEKLVRN---------------PETFKTVREIMLNVTREQLEEEEREGGVKSDMCVLCHRQEIFTVEKNIELAATPAPAPAQPS-SQELRFEHKVRLSPARESAELTRIKD---------------------------------------------------------------------------SNTQLQTENARLSVDVAALGSQITSLNTQHVALQLANSQLAAEKDSLLKEIDSLQQEHKHALQDQVTLQCLHDQLSAEYESLNKDKEQLKAAVRDLRQELRDTREQQSALEQRIEELTIQNSNMKTCSEDLS-------ILRTEHSKLTDDFRNLFATSDRFKNEYKNIQEQYKMVRMEHSSLKLQNTELSGELNAKSDQVRCLQMEYSKVQQRCEMLIQNNAELDSERKALMDNVSQLLSQYQELLAISLEDKKHFHEEEKNYTERVHSLKRQKEKLEEKIMEHYKKSETTVHKKK--PFASMLVRRVKKASSDLMNK----------------------------------VPSRNRRSWVDDARTNSQFVIG----------------------------------SESGGNESDNSNEEPLSIAS--------------------------------DTHLLQRNVPLRQSLQRDLLDNSIQRGGAVRSSLQAQKRTDLNNSRRNSVHGSLEAPDVTGSSLTLG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------TAGSRRTVYLIDEHQKLPDGSTPGATQSQSVGGSGSVNAAPPTPAEPQTPQKSTEN--------------------NAPVGPATFLMYNRINTTIGGASNSGDQ---------------------------SPLLQASG-------------------------------------------------------------------------------------SVSGTTMQDDKSARKRTEDKSNSIWYEYGCV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. :. *::*.:: *::: . : *: : .*:** :::.: :*** * *: : : *. .* * *: ::*::*.:::* * * *:: **:.: :.:.* * :.:*::* :* *:**.**** .** :* :** **:*** .** *::**..:. *: : :: :..:.: . :. . : : : : : ::* . : :: : . .* :: *. : *..: :***** ** ::: *: *****:*:*:* : :.*:: ::* :*:. : ::*: . *****:* ***:* :.:*** :: : :*** * .***:*:******* *:*:* ****** * * :: .**.* :: :.*::*: ::** *:.::*:**** *:: :: ::.: .* :.:::* : :: :*: :*.: *.:* **** **: * :::: *::: :.*. : *****::.** * :*::* :::: .* . ::* : :: :.*:::::. :: : . ** : * :: :. : :: * *::* *:: . : :.. *: : ::** * ::. :* .:: *::: * **. :: : * *.. *::. :* .** *.* * .:. :* ***::*::* .* :. . ::***::** .* :: .:*:**. *: * . : *. *: .* : : . *. . . :. :: : :. * : : . . . :. . : ** ::** .* *:.:.*:*.*: ::*.** ::* :*: ** :* :.* :: :. . :*: * ::: ::*** * :: **: * *. * : :: : :: : :. : * * : *: * :. .: ::: **..:: : * :: . .. :*: .. . . : .:* : :::. :*::::**:* : :.:*:.*.: *:.::. * .* * ** .:*.*: :***:*:* :::::*:*:*********::** :.. :*.. *. :.: :* ... :: . : . . ..: . ..: . : : . .: : * . : *.. .*. ... . :** : . *:: . . : . . :.. ::: *:..:. :.: * . . ::.. : : : . . . : : : . : ...* . ...:::*******", "identical_positions": 294, "similar_positions": 526, "identity": "13.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100422-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H792-1", "uniprot_id": "PEAK1_HUMAN", "id": "Q9H792-1", "name": "Inactive tyrosine-protein kinase PEAK1", "aln": "MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDPEKAPITHGNVKTNANHSNNHRIRNTGNFRPPVAKKPTIAVKPTMIVADGQS-ICGELSIQEHCENKPVIIG-----WNRNRAALSQKPLNNNNE-DDEGISHVPKPYGNNDSAKKMSDNNNGLTEVLKEIAGLDTAPQIRGNETNSRETFLGRINDCYKRSLERKLPPSCMIGGIKETQG--KHVILSGSTEVISNEGGRFCYPEFSSGEESEEDVLFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVDKKWNTIPLRNKSLQRICAVDYDDSYDEILNGYEENSVVSYGQGSIQSMVSSDSTSPDSSLTEESRS-ETASSLSQKICNGGLSPGNPGDSKDMKEIEPNYESPSSNNQDKDSSQASKSSIKVPETHKAVLALRLEEKDGKIAVQTEKEESKASTDVAGQAVTINLVPTEEQAKPYRVVNLEQP-LCKPYTVVDVSAAMAS---EHLEGPVN-----------SPKTKSSSSTPNSPVTSSSLTPG------------QISAHFQKSSAIRYQEVWTSSTSPRQKIPKVELITSGTGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNNAGMPPFPIIIHDEPTYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTT--SVISHTYEEIETESKVPDNTTSKTTDCLQTKGFSNSTEHKRGSVAQKVQEFNN--CLNRGQSSPQRSYSSSHSSPAKIQRATQEPVAKIEGTQESQMVGSSS--TREKASTVLSQIVASIQPPQSPPETPQSGPKACSVEELYAIPPDADVAKSTPKSTPVRPKSLFTSQPSGEAEAPQTTDSPTTKVQKDPSIKPVTPSPSKLVTSPQSEPPAPFPPPRSTSSPYHAGNLLQRHFTNWTKPTSPTRSTEAESVLHSEGSRRAADAKPKRWISFKSFFRRRKTDEE--DDKEKEREKGKLVGLDGTVIHMLPPPPVQRHHWFTEAK-GESSEKPAIVFMYRCDPAQG----QLSVDQSKARTDQAAVMEKGRAENALLQDSEKKRSHSSPSQIPKKILSHMTHEVTEDFSPRDPRTVVGKQDGRGCTSVTTALSLPELEREDGKEDISDPMDPNP----CSATYSNLGQSRAAMIPPKQPRQPKGAVDDAIAFGGKTDQEAPNASQPTPPPLPKKMIIRANTEPISKDLQKSMES--------SLCVMANPTYDIDPNWDASSAGSSISYELKGLDIESYDSLERPLRKERPVPSAANSISSLTTLSIKDRFSNSMESLSSRRGPSCRQGRGIQKPQRQALYRGLENREEVVGKIRSLHTDALKKLAVKCEDLFMAGQKDQLRFGVDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLNNYAVKICKSKAKESQQ-YYHSLAVRQSLAVHFNIQQDCGHFLAEVPNRLLPWEDPDDPEKDEDDMEETEEDAKGETDGKNPKPCSEAASSQKENQGVMSKKQRSHVVVITREVPCLTVADFVRDSLAQHGKSPDLYERQVCLLLLQLCSGLEHLKPYHVTHCDLRLENLLLVHYQPGG---------TAQGFGPAEPSPTSSYPTRLIVSNFSQAKQKSHLVDPEILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEREYTRADLPRIPFRSPYSRGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQTFTACPSLVQRNTLLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSCIVKILQHR-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q69Z38-1", "uniprot_id": "PEAK1_MOUSE", "id": "Q69Z38-1", "name": "Inactive tyrosine-protein kinase PEAK1", "aln": "MSACNTFTEHVWKPGECKNCFKPKSLHQLPPDSEKTPITHGSGKTNANHSNNHRVRSTGNFRPPVAKKPTIAVKPTMMVADGQS-VCGELSIQEHCENKPVILG-----WNQNKTSLSQKPLNNNSEGDAEGFGSDPQQCANNDSAQKISNNNNGLTEVLKEIAGLEATPPVRGNETNARETFLGRINDCYKRSLERKIPPSCMTGSMKDSQG--KHVILSGSAEVISNEGGRFCYPEFSSGEESEEDVLFSNMEEEHESWDESDEELLAMEIRMRGQPRFANFRANTLSPVRFFVSKKWNTIPLRNKSLQRICAVDYDDSYDEILNGYEENSGVSYGQGSVQSTISSDCTSPGSSFTEESRS-ETASSLSQKVCNGGISPGNPGNSKDIAETESNFESPPGNNEEKDESLTSKSSVKVPETHKAVLALRLQEKDGKIAVHTEKPESKASTDIAGQAVTISLVPVEEQTKPYRVVNLEQP-LCKPYTVVDVSAAMAS---EHLG---------------RPKIKGSSSTPNSPVTSPALTPG------------QINAHLKKSSAIRYQEVWTSSTSPRQKIPKIELSTGGPGPNVPPRKNCHKSAPTSPTATNISSKTIPVKSPNLSEIKFNSYNNAGMPPFPIIIHDEPSYARSSKNAIKVPIVINPNAYDNLAIYKSFLGTSGELSVKEKTT--SVISHTYEEIETESKVSDSTPSKLTDCPQAKGFSNSTERKRGSVAQKVQEFNN--CLNRGQSSPQRSYSSTHSSPAKIQRPTQEPAGKTEGAQGSQVPGSSSNSTREKASAVLCQIVASIQPPQTPPEAPQSSPKACSVEELYAVPPDADTTKSIPKNPPVRPKSLFTSQSSGEGEAHQTTESPTAKIQKDPSTKPVTSPPSKLVTSAQSEPPPPFPPPRSTSSPYHASNLLQRHFTNWTKPTSPTRSTEAESILHSEGSRRAADAKPKRWISFKSFFRRRKTDEE--EEKEKEREKGKLVGLDGTVIHMLPPPPVQRHHWFTEAK-GEASEKPAIVFMYRCDPDQG----HLSVDQSKAG------AEKGRAEEVLLRNSEEKKSSYLPSQIPDKACSRVTHEVAGELSPRDPRTPAGKQDG---TSVTPTLPPPDLEREEEKDDTLDPTDVSP----CSATYSNLGQSRAAMIPPKHPRHPKGAVDDAIAFGEKTDQEGLNASQPTPPPLPKKMIR-ANTEPISKDLQKAMES--------SLCVMANPTYDIDPNWDASSAGSSISYELKGLDVESYESLERPLHKERPVPSAANSISSLATLSVKDRFSNSMESLSSRRGLSYRQTRSIQKPQRQALYRGLDNREEVVGKLRSLHTDALKRLAVKCEDLFMAGQKDQLRFGVDSWSDFRLTSDKPCCEAGDAVYYTASYAKDPLSNYAVKICKSKAKESQQ-YYHSLAVRQSLPVHFNIQQDCGHFLAEVPSRLLPWEDPDAPEKAEDGTEDSEEEGKAETLGGNPEPCSETEPSQKENQRVTNRKQRSHVVVITREVPHLTVADFVRDSLAHHGNSPDLYERQVCLLLLQLCSGLEHLKPYHVTHCDLRLENLLLVQHQPGG---------AAQGPSPADPCPTLACPTRLIVSNFSQAKQKSHLVDPQILRDQSRLAPEIITATQYKKCDEFQTGILIYEMLHLPNPFDENPELKEKEYTRTDLPRIPLRSPYSWGLQQLASCLLNPNPSERILISDAKGILQCLLWGPREDLFQIFTTSATLAQKNALLQNWLDIKRTLLMIKFAEKSLDREGGISLEDWLCAQYLAFATTDSLSYIVKILQYR-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B757-1", "uniprot_id": "A0ACD6B757_DANRE", "id": "A0ACD6B757-1", "name": "Inactive tyrosine-protein kinase PEAK1", "aln": "MSACNTFTEHVWKPGECKNCFKPKSLHRSPESASECKTNINAKLTNSQRSTSS--SRAGQVRPPVAKKPTIAVKPTMMLPCSPPGLDSEGNVPRLAEGPQVTKSSPFTVWNHN-SLNSLRPAGTNNN-QGEDLVGQTEAYS-AISLQPTSSNNNGLTDVLKEIAGLGSSP------STSRNDFFGRICSSYRRSLERGLPAASCLHAGSSGRGAMKRVSLSDSTEVISTEGGRFCYPEFSSDGDDEEEDSDEDDDGEHDSWDESDEELLAMGIRMRGQPRFANFRAATLSPVPFALVKKWNTVPLRNRSLQRFCAVDYDDSYDEILNGYP--SVDSNGAPALLSYTSDHQGSGFLSTSESTTSPESLASLPEETCTE--------SSRDTDDHRNGFPFPP----NKETSSRGPSSPKSNETHKAVLAIRLEEQD-----DSQREGGALPQALPGQPITISFSPTEEQAKPYRVVNLEKAPICKPYTVVDVSASMATKDNTHLSEITPKSSVTVDPCPVSPISPQSPRSPMSPVTSPSISLSPLMPQSPIGSSSGLSGFRTKPGSIRYQEVWTSCTSPRQKIPKVDLTSG----SADPRLINHKSAPTSPTAAFGSARTVPTKSPNLSEIKFNSYNNAGMPPFPIIIRDEPAYARSSKKAVKVPIVINPSAYDNLAVYKSFLGLNGELPHSKPGAGERVASHTYEEIG-SSESSQPSPSEQKPPPISADLTATGELRTTTVNDGKYRTTTGVAFHAGIQSTNPAFLA-HSSLDRIRNPSSE--QPPEGSKDCQLASSGSSGQREKASAVLSQIVSSIQPPVSPPESLAGQSKTCSAEELYSLPPDASRDTTVN-----RPKSLHCS-------AEPHKETPHKLLPKSQSASAAVPP-----TSPKSETSAPFPPVRSSSSPYHSSNLLQRHFN-WTRPAG-AKSTDGETSPGAEGRRSSDGNKPKRWISFKSFFRRRKDEDEQKEKMEREKEKGKLLGLDGTVITVLPPPPLQRQQWFSESKTDDPLQKPTIIFTYKSESATGGEEAELRVEEHKES-------VTAEGGASSLSTPPKSRASLLISKVMNQLPVQETEISSATSLPAKLELSPLREPPASCPPPASPTSNSSRQADPEEEGIAHTISRSPESNSCRATYTNLGQSRANMIPVKHPRHPK-ASDDTLTSDPEVSELTN---KSTPPPLPKKLVPRAQIDSSAAGKELAPRPKGEARPGGTSLSVANPLYDLESTWDTASQSSSLSSEARHHD-ESGDSLERPVGGR----SLSCLTSSTSMQGCDRRGYRSTESLTAR----TRGPGRLTKGQKQMPYRGMESWEEVVGRIRGLHTDTLRKLATRCEDRFMAGQKDHLRFGTDSWSHFRLTAGKPCCEAGDAVYYTASFAKEPLMNYAVKICRGVVKETQQQFFHSLAVRQSIAVHFNIQQDCGHFLADVPARLLPWEQKE--DKDERGGTEGGEDEKEDAAGPGGKLC-------------------SCVVVITREVPFQTVADFVREGVERHARNPELYERQVCLLLLQLCAGLEHMKPYHVTHCDLRLENLLLVHCQPGNPWNLELLEPNNNAASGSSTAAASACPARLIISNFSQAKLKNVVLEPASLRDHSRLAPELLTATQYRKCDEFQTGILIYEMLHRPNPFEDSPELKEREYCSSDLPQLPLRSLYSNGLQQLATLLLNPNPSERIQMADARACLQCLLWGPREDLFNSLNPGAGTVQRHTVLQNWLDLKRTLMMIKFAERSLESGCGVSLEDWLCCQYLAFSTTESLSRVIKILQQPQGVLI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***************************: * ...: . . **:::*.. :*:.****************::. . . : .* .: . .*. * . **:* : * :* ..*.: : *.: .: . * : *.******:******** ::* :.:*: *:*** ..*:***** :*.:. . .. :* *:* **.*:****.************. :.**: .: : **:************ ************** ***** * : *****:****:****:**************** * * * :: * *.. * * :*.: * *: :**.:: *. .*:* : . .: *. :*: * . ** * ********:**:*:* .::: . . :.**.:**.: *.***:*********:. :***********:**: ** * *. :* *****.::: . :... *..:*********.*********::* :. .. ** **********: *::*:*.*************************:***:******:*:********.******:****** .***. .: : * ******* .*: .: :.*: . : .:: : * : :* : . .. .:: * .*.: :: : *** :*:..:.* **:: .*: .*.* *****:**.***:***** :***: . .*:**.****::****. .: *****. * * .::* : *. * ...... **.:**...**** **:*****:.*******. **:*:. ::**:.*: :** * : . **************** ::* :. *:*:*****:******* :*****:**::**:*:* .:. :**:*:* *:.:. * .* *:: * .... * . :.:: *:: .: : *. : * . . :: .. :.. . .. : : ::. .. . .* * ***:******* *** *:**:** * **::: . :..: :.********:: *: :. : . : : .. : :*** **::..**::* .**:* * : * ** :*****: . * : ** : . . * .* ***::* * : * *:* ***::. *****::*.****:*::**.:*** *******:****.****.****:.***************:**:** *******:. .**:** ::********:.**************:** ******: : :* * . : *: * :: * . : * * ********* *******:.: :*...*:**************:****:******************: ***. :. . :....: : *:***:******* *. :::* ***:******::*****:**************** ****::.*****:** :***::*:** ** ******: ********** ::**:. *************: :.. . .*::::******:****:******:**: *:*******.*****:**:*** ::**** ", "identical_positions": 850, "similar_positions": 458, "identity": "46.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100422-10", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86VR8-1", "uniprot_id": "FJX1_HUMAN", "id": "Q86VR8-1", "name": "Four-jointed box protein 1", "aln": "MGRRMRGAAATAGLWLLALGSLLALWGGLLPPRTELPASRPPEDRLPRRPARSGGPAPAPRFPLPPPLAWDARGGSLKTFRALLTLAAGADGPPRQSRSEPRWHVSARQPRPEESAAVHGGVFWSRGLEEQVPPGFSEAQAAAWLEAARGARMVALERGGCGRSSNRLARFADGTRACVRYGINPEQIQGEALSYYLARLLGLQRHVPPLALARVEARGAQWAQVQEELRAAHWTEGSVVSLTRWLPNLTDVVVPAPWRSEDGRLRPLRDAGGELANLSQAELVDLVQWTDLILFDYLTANFDRLVSNLFSLQWDPRVMQRATSNLHRGPGGALVFLDNEAGLVHGYRVAGMWDKYNEPLLQSVCVFRERTARRVLELHRGQDAAARLLRLYRRHEPRFPELAALADPHAQLLQRRLDFLAKHILHCKAKYGRRSGT-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BQB4-1", "uniprot_id": "FJX1_MOUSE", "id": "Q8BQB4-1", "name": "Four-jointed box protein 1", "aln": "MGRKMRGAAAAAGLWLLALSSLLTLWGGLLPPRTELPASRPPEDRLPPHPIQSGGPAPEPRFPLPPPLVWDARGGSLKTFRALLTLAAGADNPPRRHQDDRGRHEPSGLSWPEERRAVHGGVFWSRGLEEQVPRGFSEAQAAAWLEVARGARVVALDRGGCGRSSNRLARFADGTRACVRYGINPEQIQGEALSYYLARLLGLQRHVPPLALARVEARGAQWVQVQEELRTAHWTEGSVVSLTRWLPNLTDVVVPEPWRSEDGRLRPLRDAGGELTNLSQAELVDLVQWTDLILFDYLTANFDRLVSNLFSLQWDPRVMHRATSNLHRGPGGALVFLDNEAGLVHGYRVAGMWDKYNEPLLQSVCVFRERTARRVLELHRGQDAAARLLRLYSRHEPRFPELAELSEPHAQLLQRRLDFLAKHILHCKAKYGRRPGDLITLRGREGLGYE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QZU9-1", "uniprot_id": "F1QZU9_DANRE", "id": "F1QZU9-1", "name": "", "aln": "----MRLVIMKAGKVKLCAS--LCVWLGIVT--------------------WIGN---VKLHLLSVFVQQDTDRGVLFSVANNQVNNTEINAPG--MRGAKSFNIRSALILDN---VIEQRVFWSAWLEALATRVFGVEHERKWRERVRDARVVALEAG-CGRPTNRLASFADGTRACVRYGIDADQVLGETLSYYLAELLGIS-NLPPLSLSKLNLSSEQWASVRENIEVLEWSPNAIVSLTEFIPNVTGVFIPAHLQKQQ------QLSAESLSNMTLSYLLELMQWGDLILFDYLTANFDRIVSHIFSLQWDARVMERTTNNLLKTVNGDLLFIDNEAGLVHGYRVLDLWERYHKILLSSSCMFRRSTVRRVSELKRSGNSAKLLYELYRAREPLARELGSLSEEHALTLQSRIDVVYKHIKLCTEIM-------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** . ** *. . * :* *::. *. . *. : *: * * :. . : : * :. : : : .:. **** ** .. *. : * * .*.**:***: * ***.:**** *************:.:*: **:******.***:. ::***:*:::: . **..*:*::.. .*: .::****.::**:*.*.:* :.:: : :. .*:*:: : *::*:** **************:**::******.***.*:*.** : .* *:*:************ .:*::*:: **.* *:**. *.*** **:*. ::* * .** :** **. *:: ** ** *:*.: *** *. ", "identical_positions": 164, "similar_positions": 119, "identity": "36.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100422-12", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BU25-1", "uniprot_id": "PAMR1_MOUSE", "id": "Q8BU25-1", "name": "Inactive serine protease PAMR1", "aln": "-----MELDRWAQLGLVFLQLLLI------SSLPREYTVINEACPGAEWNIMCRECCEYDQIECLCPGKKEVVGYTIPCCRNEDNECDSCLIHPGCTIFENCKSCRNGSWGGTLDDFYVKGFYCAECRAGWYGGDCMRCGQVLRASKGQILLESYPLNAHCEWTIHARPGFIIQLRFGMLSLEFDYMCQYDYVEVRDGDNSDSPIIKRFCGNERPAPIRSTGSSLHVLFHSDGSKNFDGFHAVFEEITACSSSPCFHDGTCLLDTTGSFKCACLAGYTGQRCENLLEER--------------------------------------------------------NCSDLGGPVNG-----------------------------------------------------------------------------------------------YKKITEGPG----------------------------------------------------------------------------LLN-------------------------------------------------------------------------------------------------ERHVKIGTVVS-------------------------------------------FFCNGSYVLSGNEKRTCQQNGEWSGKQPVCMKACREPKISDLVRRRVLSMQVQSRETPLHQLYSTAFSKQKLQDASTKKPALPFGDLPPGYQHLHTQVQYECISPFYRRLGSSRRTCLRTGKWSGRAPSCIPICGKIESTPSPKTQGTRWPWQAAIYRRTSG---VHDG------GLHKGAWFLVCSGALVNERTVVVAAHCVTELGKATIIKTADLKVVLGKFYRDDDRDEKSIQNLRVSAIILHPNYDPILLDTDIAVLKLLDKARISTRVQPICLATTRDLSTSFQESHITVAGWNILADVRSPGFKNDTLHYGMVRVVDPMLCEEQHEDHGIPVSVTDNMFCASKDPSTPSDICTAETGGIAALSFPGRASPEPRWHLVGLVSWSYDK-TCSNGLSTAFTKVLPFKDWIERNMK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UXH9-1", "uniprot_id": "PAMR1_HUMAN", "id": "Q6UXH9-1", "name": "Inactive serine protease PAMR1", "aln": "-----MELGCWTQLGLTFLQLLLI------SSLPREYTVINEACPGAEWNIMCRECCEYDQIECVCPGKREVVGYTIPCCRNEENECDSCLIHPGCTIFENCKSCRNGSWGGTLDDFYVKGFYCAECRAGWYGGDCMRCGQVLRAPKGQILLESYPLNAHCEWTIHAKPGFVIQLRFVMLSLEFDYMCQYDYVEVRDGDNRDGQIIKRVCGNERPAPIQSIGSSLHVLFHSDGSKNFDGFHAIYEEITACSSSPCFHDGTCVLDKAGSYKCACLAGYTGQRCENLLEER--------------------------------------------------------NCSDPGGPVNG-----------------------------------------------------------------------------------------------YQKITGGPG----------------------------------------------------------------------------LIN-------------------------------------------------------------------------------------------------GRHAKIGTVVS-------------------------------------------FFCNNSYVLSGNEKRTCQQNGEWSGKQPICIKACREPKISDLVRRRVLPMQVQSRETPLHQLYSAAFSKQKLQSAPTKKPALPFGDLPMGYQHLHTQLQYECISPFYRRLGSSRRTCLRTGKWSGRAPSCIPICGKIENITAPKTQGLRWPWQAAIYRRTSG---VHDG------SLHKGAWFLVCSGALVNERTVVVAAHCVTDLGKVTMIKTADLKVVLGKFYRDDDRDEKTIQSLQISAIILHPNYDPILLDADIAILKLLDKARISTRVQPICLAASRDLSTSFQESHITVAGWNVLADVRSPGFKNDTLRSGVVSVVDSLLCEEQHEDHGIPVSVTDNMFCASWEPTAPSDICTAETGGIAAVSFPGRASPEPRWHLMGLVSWSYDK-TCSHRLSTAFTKVLPFKDWIERNMK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QE83-1", "uniprot_id": "F1QE83_DANRE", "id": "F1QE83-1", "name": "Inactive serine protease PAMR1", "aln": "MSSSVCLHSSHSSICLSFIIIIIITLLEHCSAWPYDYRFVPSWCPGPEWSVLCRGCCEYDVIRCKCPLQGAPVGYAVPCCRNAADECDPCTIHPGCSIFENCKRCNNGTWA-PRDDFFLKGQYCAECRPGWSGGDCMTCGGLIHKRQGHLVLESYPNNARCEWTLRVDRPYTIDLRFMMLSLEFDHSCQYDYVEVRDGDSLNSRLIGRYCGNERPPPIRSSGSSLHLLFVSDGYKHFDGLFAIFQESSECISSPCLHDGTCVVDSSRSYHCACLAGYTGKRCEHVLECRRPLIPAHGSMRHLDERVGGHVVFQCEPGHTLKGFRISTCLLDGSWSSPTPQCVPFQNCGIPPKPENGDHFLVYGPNDVLIAIQYFCYKQYKLKGAPQRTCLGNNTWSGTAPTCITEPDVIPTADHEQDKGKVKPSGADDVGDAKNKTSQEEENESKPDKDIKAQKPTAGKGYDLVLGKDVEKEIVSIFVKEKPKAEYKESDSSINTIEKKDPGEDKDTLKVLGKDEHLHIEEKVVTPSRDVELVDIVLIDNQMENKTTDDNTGREYTISRLNEDRKENLLNEVDVTQQENNTGFFDSNDIDENADTPRLKQTEEPPSPTAVHYSTETTTTASRSTARAAVKPALQEDPQHVETADVQQEPTAESPPTAQNEAGEVTPCPPPPPLYHGFSERVSGVRPETLRFFCNQSYALVGSDRRTCQADGSWSGAQPVCIRACREPKVSVLVRQKVLPPHVPSRKTPVHKFYSSSVSTVFLKDVRATQSPLSLPTLPQGFHHLYTHIEYECASQYYQHSGSSRRTCLKMGKWSGRHVSCSPVCGKLSSFDPQKPEQTQWPWLASIYRRPAGKLKLKSGKEDQAEDQAEDGWQLVCSGALVNQRSVVVAAHCVTELGKTHPLDPHTLRVTLGKHYRSERRHTKGLQTVRVSSIALHPTFDPLVLDSDVAVLKLLDKARIGEHVVPVCLPDP-----QLTADQGLVTGWSLEPDP--ADADGERARVGHVLMGDTVQCEQQYASHGLPISVSENMLCG--RQAERSNICPADTGGIL-LSPAGSAHTPQHWTLLGLVSFGFESSVCSSELYTVYTHIANFVSFIEANMT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.: * *: :::* *: * :* .: . ***.**.::** ***** *.* ** : ***::***** :***.* *****:****** *.**:*. . ***::** ******.** ***** ** ::: :*:::***** **:****::. : *:*** *******: ************. :. :* * ******.**:* *****:** *** *:***:.*:::* : * ****:*****::*.: *::*********:***::** * **. * ** :* * * * *:: :*.: . * . **** **.* *.::**** :*.*** **:*::******:* ***::**. :* **:**:*::**::.*. *:.. :.:..*.: ** *::**:*:::*** * :*:: ********: ****** ** *:***:.. . *.: :*** *:****.:* ::.* . :..* *********:*:*********:***. :.. *:*.***.**.: *. * :*.:::*:* ***.:**::**:*:*:*********. :* *:**. . .: .: *:**.: .* .. ..: : * * : *.: **:*: .**:*:**::**:*. : *:**.*:**** :* .* * . :* *:****:.::. .** * *.:*:: * .:** **.", "identical_positions": 356, "similar_positions": 217, "identity": "32.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100422-13", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N961-1", "uniprot_id": "ABTB2_HUMAN", "id": "Q8N961-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "aln": "MAGTYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVMASHSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYNGGS-LGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGASPARQARQPPQPITWSPDALHTLYYFLRCPQMESMENPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSGDIRQAARLLLPGLDCEPRQLKPEHCFSSFRRLDARAATEKFNQDLGFRMLNCGRTDLINQAIEALGPDGVNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIQVPSNSPRHPSIHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNGGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEAHGMGSSLHEDMNCFSHSAAHGHRNVLRKLLTQPQQAKADVLSLEEILAEGVEESDASSQGSG---SEGPVRLSRTRTKALQEAMYYSAEHGYVDITMELRALGVPWKLHIWIESLRTSFSQSRYSVVQSLLRDFSSIREEEYNEELVTEGLQLMFDILKTSKNDSVIQQLATIFTHCYGSSPIPSIPEIRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDSSKTIEISDMKYHIFQMMMQYLYYGGTESMEIPTTDILELLSAASLFQLDALQRHCEILCSQTLSMESAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQDAFRQLIYGRSSKVQGLDPLQDLQNTLAERVHSVYITSRV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TQI7-1", "uniprot_id": "ABTB2_MOUSE", "id": "Q7TQI7-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "aln": "MAGTYSSTLKTLEDLTLDSGYGAGDSCRSLSLSSSKSNSQALNSSAQQHRGAAWWCYSGSMNSRHNSWDTVNTVLPEDPEVADLFSRCPRLPELEEFPWTEGDVARVLRKSVGGRRLPSFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVLASQSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYNGGS-LGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGTSPARQARQPPQPITWSPDALHTLYYFLRCPQMESMENPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSPTVDSGDIRQAARLLLPGLDCEPRQLKPECCFSSFRRLDARAATERFNQDLGFRMLNCGRTDLISQAIEALGPDGVNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIQVPSHSPRHPSVHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNSGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEANGMASSLHEEMNCFSHSAAHGHRNVLRKLLTQPQQAKADVLSLEEILAEGVEESDTSSQGS----SEGPVRLSRTRTKALQEAMYYSAEHGYLDITMELRALGVPWKLHIWIESLRTSFSQSRYSVVQSLLKDFSSIKEEEYNEELVTEGLQLMFDILKTSKNDSVLQQLATIFTHCYGTSPIPSIPEIRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDSSKTIEISDIKYHIFQMLMQYLYYGGTESMEIPTADILQLLSAANLFQLDALQRHCEILCSQTLSVESAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQDAFRQLIYGRSSKVQGLDPLQDLQSTLAERVHSVYVTSRV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F2F4-1", "uniprot_id": "E7F2F4_DANRE", "id": "E7F2F4-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "aln": "MAAVSNSTMKTLEDLTLDSGYGAGDSYRSLSLSSSKSNSQALVSSPQRGN---WWSYTGSMNSRNNSWDTVNTVLPEDP--EDIISKCPRLPELEEFPWTDEEIDVVLRKVAGEG--LCFAPESVRSVSVLMRRALLRISREAQRLSVVHCRCTRFEVQSAMKLVMSWALAESCVSAAIRAISLYSMSAGEVLRKSKSSRCALSLSVGRFFRWMVDTRISVRVHEYAAICLTACIENLVQEIGLRVLLAAQN---GTNSYPVTAEALEAVVCNDAEIFGLVQNYEHLICGKNANGELSLPAHFSLYAEGPDAAVESRETAYAQLELRTLEQALLATCVGSLSELSDLVSRAMHHMQRLVSTSPGLSPGRPFCL--QPISWSPDALHTLYYYLRSPQMESLENPNLEPQRIALNKERPFPLLPPLMEWMRVAMVHAEHRRSLLVDSDDVRQTARLLLPGLDCEPRQLKPECCFTSFKRLDSKAAMDKFNLDLGFRMLNCGRTDLIGQAIQLLGRDGVNTMDDQGMTPLMYACSAGDEALVHMLIDAGANLDVAVPNCSPKHPSVHPESRSWVALTFAVLHGHISVVQLLLDVGADVEGRALRNSHHSSAETPLQLASASGNYEMVSLLLSRGADP---MLRVH-LTSSLYEGMNCFSHAAAHGHRNVLRKLLSEPQRLQEDVLSLEEILAEGREEQEKLEKNGGNMKSVCTSQLCKARIRALQEASLHSAEHGYLDVSMELRALGVSWKLHVWLESIRSAQLHSRTELTLSLLKDFTIIGEEKYCEELLAEGLPFLFSIIKTTKNKDIRKQLAAVFCHCVCSTAAPSILAVKDTPTAQLDAHFLNNSEMSDVIFVVEGRPFYAHRVLLMSASQRFRDLLSLYQSNGTSDHMAIEITDIKYNTFKMMMAHLYCGGAECLDVSASDLLKLLPVAHSFQLPVLKRHCEILCSERINLNNAVSIYRTAKVSEAVELVVFCEGFILQNMVDLLDCEAFEELLLDP-------EVLDGLQATLASRLHSLCGPRRA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.. .**:***************** *************** **.*: . **.*:******:************** *::*:*************: :: **** .* *:.*:** :: *:****:*::********:*.:*********::** ********. **::*:********: **:.**:**.*::*****************:******.****:****:** **: : . *:.. *:***** *: ****::*::* ************ *****:** * *. . :.* ************:********:*************** . .** **.* ***:***********:**.*****:*****:* *::**:**** ************:.:****** ***.*:**:****************** **:**:***::** ::** ***************.***: ** ******************:*****:*:**********: **. **:***:**:** *.:******************.**.*** *:.....* **********:****:*********** **..: : ***:* ******:*************::**: : ************ **.: .:.. * . :*.::* :***** :******:*::********.****:*:**:*:: :** .:. ***:**: * **:* ***::*** ::*.*:**:**..: :***::* ** ::. *** ::.* .*:**.*****.***** *:***: ****:***::**:**: *:: ..:. .. :***:*:**: *:*:* :** **:*.:::.::*:*:**..* *** .*:********: :.::.**. *: **: :* **.:*****:*::* **: :**.:*: . : *:.** ***.*:**: . *.", "identical_positions": 647, "similar_positions": 237, "identity": "62.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100422-14", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N961-1", "uniprot_id": "ABTB2_HUMAN", "id": "Q8N961-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGTYSSTLKTLEDLTLD-------------SGYGAGDSCRSLS---------------------------------LSSSKSNS-----------------------------------QALNSSAQQHRGAAWWCYSGS-MNSRHNSWDTVNTVLPEDPEVADLFSRCPR---------------------------------------------------------------------------------LPELEEFPWTEGDVARVLRKGAGGRRLPQFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVMASHSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYN-GGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGASPARQARQPPQPITWSPDALHTLYYFLRCPQMESME-NPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSGDIRQAARLLLPGLDCEPRQLKPEHCFSSFRRLDARAATEKFN-------------------------QDLG--------FRMLNCGRTDLINQAIEALGPDG-VNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIQVPSN-SPRHPSIHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNGGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEAHGMGSSLHEDMNCFS---HSAAHGHRNVLRKLLTQPQQ-AKADVLSLEEILAEGVE-ESDASSQGSGSEGPVR--------------LSRTRTKALQEAMYYSAEHGYVDITMELRALGVPWKLHIWIESLRTSFSQSRYSVVQSLLRDFSSIREEEYNEELVTEGLQLMFDILKTSKNDSVIQQLATIFTHCYGSSPIPSIPE---IRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDSSKTIEISDMKYHIFQMMMQYLYYGGTESMEIPTTDILELLSAASLFQLDALQRHCEILCSQTLSMESAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQ-DAFRQLIYGRSSKVQGLDP--LQDLQNTLAER-------VHSVYITSRV-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TQI7-1", "uniprot_id": "ABTB2_MOUSE", "id": "Q7TQI7-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGTYSSTLKTLEDLTLD-------------SGYGAGDSCRSLS---------------------------------LSSSKSNS-----------------------------------QALNSSAQQHRGAAWWCYSGS-MNSRHNSWDTVNTVLPEDPEVADLFSRCPR---------------------------------------------------------------------------------LPELEEFPWTEGDVARVLRKSVGGRRLPSFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVLASQSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYN-GGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGTSPARQARQPPQPITWSPDALHTLYYFLRCPQMESME-NPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSPTVDSGDIRQAARLLLPGLDCEPRQLKPECCFSSFRRLDARAATERFN-------------------------QDLG--------FRMLNCGRTDLISQAIEALGPDG-VNTMDDQGMTPLMYACAAGDEAMVQMLIDAGANLDIQVPSH-SPRHPSVHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNSGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEANGMASSLHEEMNCFS---HSAAHGHRNVLRKLLTQPQQ-AKADVLSLEEILAEGVE-ESDTSSQGS-SEGPVR--------------LSRTRTKALQEAMYYSAEHGYLDITMELRALGVPWKLHIWIESLRTSFSQSRYSVVQSLLKDFSSIKEEEYNEELVTEGLQLMFDILKTSKNDSVLQQLATIFTHCYGTSPIPSIPE---IRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDSSKTIEISDIKYHIFQMLMQYLYYGGTESMEIPTADILQLLSAANLFQLDALQRHCEILCSQTLSVESAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQ-DAFRQLIYGRSSKVQGLDP--LQDLQSTLAER-------VHSVYVTSRV-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O08764-1", "uniprot_id": "ABTB2_RAT", "id": "O08764-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGTYSSTLKTLEDLTLD-------------SGYGAGDSCRSLS---------------------------------LSSSKSNS-----------------------------------QALNSSAPQHRGAAWWCYSGS-MNSRHNSWDTVNTVLPEDPEVADLFSRCPR---------------------------------------------------------------------------------LPELEEFPWTEGDVARVLRKSVGGRRLPSFSAEAVRRLAGLLRRALIRVAREAQRLSVLHAKCTRFEVQSAVRLVHSWALAESCALAAVKALSLYSMSAGDGLRRGKSARCGLTFSVGRFFRWMVDTRISVRIHEYAAISLTACMENLVEEIRARVLASQSPDGGGAGGGEVSAEALEMVINNDAELWGVLQPYEHLICGKNANGVLSLPAYFSPYN-GGSLGHDERADAYAQLELRTLEQSLLATCVGSISELSDLVSRAMHHMQGRHPLCPGTSPARQARQPPQPITWSPDALHTLYYFLRCPQMESME-NPNLDPPRMTLNNERPFMLLPPLMEWMRVAITYAEHRRSLTVDSGDIRQAARLLLPGLDCEPRQLKPECCFSSFRRLDARAATERFN-------------------------QDLG--------FRMLNCGRTDLISQP-SSPGPDG-VNTMDDQGLTPLMYACATGDEAMVQMLIDAGANLDIQVPSN-SPRHPSVHPDSRHWTSLTFAVLHGHISVVQLLLDAGAHVEGSAVNSGEDSYAETPLQLASAAGNYELVSLLLSRGADPLLSMLEANGMASSLHEDMNCFS---HSAAHGHRNVLRKLLTQPQQ-AKADVLSLEEILAEGVE-ESDTSSQGS-SEGPVR--------------LSRTRTKALQEAMYYSAEHGYVDITMELRALGVPWKLHIWIESLRTSFSQSRYSVVQGLLRDFSSIKEEEYNEELVTEGLQLMFDILKTSKNDSVLQQLATIFTHCYGTSPIPSIPE---IRKTLPARLDPHFLNNKEMSDVTFLVEGKLFYAHKVLLVTASNRFKTLMTNKSEQDGDNSKTIEISDIKYHIFQMLMQYLYYGGTESMEIPTADILQLLSAANLFQLDALQRHCEILCSQTLSVESAVNTYKYAKIHNAPELALFCEGFFLKHMKALLEQ-MPS-----GSSS------------MAEAAKSR-------AWTHCRICRAP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3AP57-1", "uniprot_id": "A0A8M3AP57_DANRE", "id": "A0A8M3AP57-1", "name": "Ankyrin repeat and BTB/POZ domain-containing protein 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGTNSSNMKTLEDLTLD-------------SGYGAGDSCKSLS---------------------------------LSSSKSNS-----------------------------------QAFMN--TPHRG-NWWYYSGS-MNSRNNSWDTVNTVLPEDP--EDIFSKCPR---------------------------------------------------------------------------------LPELEEFPWTEEDVGRVVRKGAG--KGASFSAEAVRRLATLMRRALIRISREAQRLSVMHCRCTKFEVQSAIRLVLSWALADHCVSATVKAISMYNMSAGELLRKGKSARCGLVFSVGRFFRWMVDTRIAVRIHEYAAICLSACMEALVEEVGVRILMAERE--GATPGCVLTAETLEGVINNDAELWGVLQHHEHLICGKNANGVLSLPAHFSPYTEGRQTGLETREDAYAELELRTLEQALLATCVGSISELSDLVSRAMHHMQRLSSVRHGLSPARHARQ--QPVSWSPDALHTLYYFLRCPQMESME-NPNLDPPRMALSKERPFLLLPPLMEWMRVAIVHAEHRRSLLVDSDDVRQTARLLLPGLDCEPRLLKPECCFSSFRRLDAKAATDKFQ-------------------------LDLG--------FRMLNCGRTDLIGQAIELLGPDG-VNSMDDQGMTPLMYACSAGDEALVQMLIDAGANLDVAVPMC-SPKHPSVHADSRHWVALTFAVLHGHISVAQLLLDAGANVEGAAIRYGQENTSETPLQLASAAGNYEMVSLLLARGADPLLRSQDSNTLTSSLYEDMNCFS---HAAAHGHRNVLRKLLSQPQK-VREDVLSLEEILAEGVDGETQASGRNGHSLPPPPSPNLSLVSEDALPKLCKTRMKALQEASFYSAEHGYLDVTMELRSLGVPWKLHVWLESLRSAQQKSRAGVMLSLLRDFTSVKEEDYCEELVSVGLPLMFNILKNSKNEAIIQQLGIIFSHCYGTAPLPPIQE---KKAALAAQLDPHFLNNQEMSDVTFLVEGKPFYAHGVLLLTASDRFKTLLAQNGSDSTQTRKDIEISNIKYNIFQMMMSYLYCGGTESLKMGVSELLELLSAASLFQLGVLQRHCEILCAQNIDLDNAVNIYHTAKANGAVELSTYCEGYFLQNMAVLLER-EAFRVMILGSGARSGSGKDSLLEALEATLVRR-------LRSLLVTSRV-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PFY3-1", "uniprot_id": "M9PFY3_DROME", "id": "M9PFY3-1", "name": "BTB domain-containing protein", "aln": "MYCTKDCTCSLCRELRGYKPSDKKSAPSAPTLLSRMLNDNFILRRRGISLKNFQPQSLRNSEMLAQQMPVPRPPQTPSPTPIEELPDWATEDSSRAKKPNHKVVIYFGDSIHRGGQQSPLPSPKELHSQLLQEMSQKLKTSVAEEGLTGVEKVKKVQQMAGQPETSPPANDELPPYIESVQNGVINIRIEGNYRRASALVETVAKPTLAVVAPTKSECDCDAALGDNDDGNADDDSDDPGQDEAETDSCDWSYVQEWRRAAKRPTGNLPPNFVQHQAPSQVTGLPPVPPPQMQSPHQVQSQLPPSQTPLSSQKGLAVAMATPAPRVFKELAQQPNKGMPHKMVASSSSCSGGQANSSCKMPSPGTASKALIPQRAVAGPARLTVQSTPVKSQPPQLSGSLSQSQVSPNRPILGIPTTAANPTPPRIHQHDQFRALQRVQECHSSSDENRSSGHASMSDTGGHSSSPAGGMTLGPLPEDRLAAGVTNRSTRSRRHRGIMPGGKAPWSGTGLEDIKLAMLTLRSQTSSSTYSSLSAGSESSEPARRLGRYSSLETVVTSTSADEFVWVDSHNRLVELQHPPWSQQCILKVLRNGRCQQQAEHLAVEAVSRLGYLLQRALVRIAREIQRFSAGVGLCSKQEVVGALRVVLSSSLADSCTKACLRSAAMFAVPGESALKQSKSARAGLQLSVGRFYRWMTDARLGKFIHEYAAVYLCAGIENLLEEIALQCNG-------------TTAAALDQSIASSGDVWGLLQPFAHLNAGRIASGALALPRWANSLDQVIASSGDFRG--------------HLATCVGSIRELKEKALRTQQEFQLAAALSGSALAALFYFMRCSQLEHTELLAASGCHAGQAQSAAPGGGTSSAGHHVQELCYERAYVVLPPLAEWLRVAAAHAEHRNAMMIDKDDVMQAARLLLPGVDCPIRPVAHDEELPTKKTHFNTAPTVSSTGTGTGSSSCSSPVVSGIGIGIGEDTSELGRRATIGVAFKLLLTGRAELLAQAAQLLPPTTRYDTQNSAGLTALMIASIRNDEVALHALLDAGCDPNVEVPPAGSAGYPAIQPDTQHWTALSFAASRANYVALRILLERGGKVEGGARSS-EEKCTLTPLQLAAGTGNLEIVALLLAHGANAFLSTQQKDSLCFAGSAQKGCFCAISVAAAHGHRSCLRKLLTHPVSPGTRDVLSLEEMLAEGDVGGVRGSGGPTGAGGPNS-ASASGNNEDILPLLNKTQIKRLQEAMYHSAENNHLDITIELRKLGVPWTLHCWMHALSAAHDLRLDAVIDQLLQDFLQVCPDDYSAQFVSECLPLLFNIFRN-KNEGTTLLLADIFATCFGWETLPPVKEQPPMQPVQGSRIDPKFVNNPELSDVTFRVEGKIFYGHKIVLVTASPRFQSMLSSKLSE-GSSTPTVQINDIRYHIFQLVMQFLYCGGCSSLDVAHGDVLELMAAASFFQLEGLLRYTEARCSEMVDVDNVVAMYIHAKVYNANRLLEFCQCFLLQNMVALLTYDDSVKRLLFAKKIPNHDVLAGLLQTLQNRLKARKPNSGGGLVNSYRSPPVTPVKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 328, "similar_positions": 329, "identity": "20.76%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100422-15", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DEL3-1", "uniprot_id": "TTC17_RAT", "id": "B5DEL3-1", "name": "Tetratricopeptide repeat protein 17", "aln": "------------------MAAAIGVRGRFELLSCSGP--GWLISLSALLSVVARGALATTHWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQETTVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDVRPEDFIDTESPVPPDPEQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGLQKNSSSWVLYNLASFYWRIKNEPYQVVECTMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAALD-DSAFFTSYYTLGNIYAMLGEYNHSVLCYDHALQAKPG-FEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKEAQLGNHQICRLVNQQHSLHCQWDQPVRYHRGDIFENVDYVQFGDDSSTSSMMSVNFDVPTNQSDVSESVRSSPVAHSVLWVWGRDSDAYRDKQHILWPKRADCTDSYPRVPLGGELPTYFLPPENKGLRIHELTSDDYSSEEEAQTPDCSITDFRKSHTLSYLVKELEVRMDLKAKIPDDHARKILLSRIKNYTIPEEEIGSFLFHAINKPNAPVWLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLLIHYGLHLDATKLLLQALAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALKLTTRCPECESSLKLIRCMQFYPFLYNITSSVCSGHCHEKTLDNSHDKQKYFAKPQSLDAAEEEPSRHGADEDPVLSVENAGRDSDALRLESTVVEESNGSDEVEKSEETKMSEEILALVDEFQQAWPLEGLG---GTLEMKGRRLDLQGIRVLKKGPQDGVAKS-SCYGDCRSEDDEATEWITFQVKRVKKPKGDHKKPPGKKVEASQAENGQRYQANLEITGPKVASPGPQEKKRDYQSMGWPSPDECLKLRWVELTAIVSTWLAVSSKNIDITEHIDFATPIQQPAMEPLCNGNLPTSMHTLDHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVVVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKGRRSP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PVB5-1", "uniprot_id": "TTC17_MOUSE", "id": "E9PVB5-1", "name": "Tetratricopeptide repeat protein 17", "aln": "------------------MAAAIGVRGRFELLPRSGP--GWLLSLSALLSVVARGALATTHWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQETTVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDIRPEDFIDTESPVPPDPEQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGLQKNASSWVLYNLASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAALD-DSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQAKPG-FEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKEAQLGNHQICRLVNQQHSLHCQWDQPVRYHRGDIFENVDYVQFGDDSSTSSMMSVNFDVPTNQSDVSESVRSSPVAHSVLWVWGRDSDAYRDKQHILWPKRADCTDSYPRVPLGGELPTYFLPPENKGLRIHELTSDDYSSEEEAQPPDCSITDYRKSHTLSYLVKELEVRMDLKAKIPDDHARKILLSRIKNYTVPEEEIGSFLFHAINKPNAPVWLILNEAGLYWRAVGNSTFAIACLQRALNLAPVQYQDIPLVNLANLLIHYGLHLDATKLLLQAVAVNSSEPLTFLSLGNAYLALKNVSGALEAFRQALKLSTKCPECESSLKLIRCMQFYPFLYNATSSVCGGHCHEKPLDNSHDKQKYFAKPQSLDAAAEEPSGHGADEDPVLSVENAGRDSDALRLESTVVEESNGSDEVEKSDETKMSEEILALVDEFQQAWPLEGFG---GTLEMKGRRLDLQGIRVLKKGPQDGVAKS-SCYGDCRSEDDEATEWITFQVKRVKKPKGDHKKPPGKKVEASQAENGQRYQANLEITGPKVASPGPQEKKRDYQSLGWPSPDECLKLRWVELTAIVSTWLAVSSKNIDITEHIDFATPIQQPAMEPLCNGNLPTSMHTLDHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKGRRSP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96AE7-1", "uniprot_id": "TTC17_HUMAN", "id": "Q96AE7-1", "name": "Tetratricopeptide repeat protein 17", "aln": "------------------MAAAVGVRGRYELPPCSGP--GWLLSLSALLSVAARGAFATTHWVVTEDGKIQQQVDSPMNLKHPHDLVILMRQEATVNYLKELEKQLVAQKIHIEENEDRDTGLEQRHNKEDPDCIKAKVPLGDLDLYDGTYITLESKDISPEDYIDTESPVPPDPEQPDCTKILELPYSIHAFQHLRGVQERVNLSAPLLPKEDPIFTYLSKRLGRSIDDIGHLIHEGLQKNTSSWVLYNMASFYWRIKNEPYQVVECAMRALHFSSRHNKDIALVNLANVLHRAHFSADAAVVVHAALD-DSDFFTSYYTLGNIYAMLGEYNHSVLCYDHALQARPG-FEQAIKRKHAVLCQQKLEQKLEAQHRSLQRTLNELKEYQKQHDHYLRQQEILEKHKLIQEEQILRNIIHETQMAKEAQLGNHQICRLVNQQHSLHCQWDQPVRYHRGDIFENVDYVQFGEDSSTSSMMSVNFDVQSNQSDINDSVKSSPVAHSILWIWGRDSDAYRDKQHILWPKRADCTESYPRVPVGGELPTYFLPPENKGLRIHELSSDDYSTEEEAQTPDCSITDFRKSHTLSYLVKELEVRMDLKAKMPDDHARKILLSRINNYTIPEEEIGSFLFHAINKPNAPIWLILNEAGLYWRAVGNSTFAIACLQRALNLAPLQYQDVPLVNLANLLIHYGLHLDATKLLLQALAINSSEPLTFLSLGNAYLALKNISGALEAFRQALKLTTKCPECENSLKLIRCMQFYPFLYNITSSVCSG---------------------------------------------------------TVVEESNGSDEMENSDETKMSEEILALVDEFQQAWPLEGFG---GALEMKGRRLDLQGIRVLKKGPQDGVARS-SCYGDCRSEDDEATEWITFQVKRVKKPKGDHKKTPGKKVETGQIENGHRYQANLEITGPKVASPGPQGKKRDYQRLGWPSPDECLKLRWVELTAIVSTWLAVSSKNIDITEHIDFATPIQQPAMEPLCNGNLPTSMHTLDHLHGVSNRASLHYTGESQLTEVLQNLGKDQYPQQSLEQIGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKKAIDCLRQALHYAPHQMKDVPLISLANILHNAKLWNDAVIVATMAVEIAPHFAVNHFTLGNVYVAMEEFEKALVWYESTLKLQPEFVPAKNRIQTIQCHLMLKKGRRSP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F211-1", "uniprot_id": "TTC17_DANRE", "id": "E7F211-1", "name": "Tetratricopeptide repeat protein 17", "aln": "MTRSFRVEWTDGRKMADDKSNSIGDNSTNKRLWSSSIRGSALIFICALLAEPAR---ATTHWVVTEDGKIQQQVDSPLNLKHPHHLVLFMQQETRVNYLKKLEKQLVAQKIHIEENEDRDTGLEQRHYKEDADCVTAKVPLGDLDLYDGTFISLESKDINPEQFLDLMSALPPDLEKPDCAKLLDLPYSIHAFQHLRGVQEKVNLTSPLLSKDDPIFTSLCLKLGQSVDEVGHRIHQALLKNSSSWVLYNLASFYWRIKNEPRRAVDCVVRALHFSPRQHKDVALVNMANVLHRAHFSADAAILAHAALDLTTDLLTSHYTLGNIYAMLGEYNHSVLCYEQALQAQPG-FEQALRRKHAVLCQQKLEQRLEAQHRSLQRTLNELKEYQKQHDHYLRQQEMLDKHKLIQEEQILRNIIHETQMAKEAQLGNHQMCHMGQQKFTLHCPFDLPVRYHRGELFENVHYIQFGEEVSVASSVALVSELSVNESHSPQQSYTVSLGREPAAHWDKETTTTDESRTVLWPRRSDCAQRFPTIPPAYLLPTYYLPPESRNLKALNILLESISPPPSAKMPDCSLKNVVGNRDP-----LESMSWALEKELRDPQAAEVLLKRSGGRSL--EQTGALIAQALEKMSGPRWMMQNEAGLFWRAKGNGTQALVCLRQALHSAPPQHRDLPLVNTANLLLHYGLHSEAHELLQQALQINQSEPHTLLSLVNVHLSQGNLTGALAVFRQALSLSVHCGQCRASLPLMRCLQFYPFLYNLQHQACSSGGACEVEEDSE-----LEDWDTGSSSSGRQEVWDSDAMPVSALEDS-------LLFEKVVVDSNGSGEASGQDRTREPKAEGGEEEEQDWRLREELIGAFEGALDMNGKTGDLRGIRVLKNDRVMGARGGGPCFGNC--EDDEGAEWITFQVKRVKKPKSDASEGWVGEGDVRQTEP-TASNSILEISGPTIPSPGPSERWKDYSSLGWPGPEECQRTRRVDLTTVASTWLAVSAKNIDITEHIDFATPLQEPAVEPVCNANLPASMHTLDHLSGVANRGGIHYTGESQLREVLQNLGKDKFPSQSFEQVGTRIAKVLEKNQTSWVLSSMAALYWRVKGQGKRAIDCLRQALNYAPHHMKDVPLISLANIFQNARLWEDALTVARMAVEIAPHFVVNHFTLANVYIAMEEFEKAMHWYESTLKLQPEFGPAKDRLRTIQCYLLSKRDRRAP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4J6-1", "uniprot_id": "Q9W4J6_DROME", "id": "Q9W4J6-1", "name": "Tetratricopeptide repeat protein 17", "aln": "--------------------------------------MRLCPLAFAVLLGLFHLIQACNHWVLREE-QIVPKLDSPFHMREPHNLAAFLKQIRYSEYVERSYLDLLRKREQIVEHLRFSMRFGEDLAEQAKCAMDYYMLEKRMSYLKITPEQLKRINLPDQRQLHIQKSASSMGMEPICSDYHRLSVGPATYDHLESFRPEVLAAAFLEREHDTNVGMATVELTR------RFAVDGLQHHPASWKFHTLSSYYWRMRGNAREALPCARLAALLAPPIFKDIPLLSLGTILFRMGRLADADLILTAAVEHAPNVAENHVVLASALAMKHDFNRSLQHFDEAERLDPSTLPRTQQVRNFISCLENLTKKTSKMYSYVKYMQNEVKEFKKLKHHISQNHERLIQQQLPLGARRLLGLDAKTNNDDLHRRGQYCSTRTPNG-------SDEPVLFCD----------FYSDMQMRLESKDVDIDVLERDLKANTDAVIRQVSTEIRKQFNLEQLKAAKAQMPAKATKAT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:* : * .***: *: :* ::***::::.**.*. :::* :*::. :*: :: :* *: . : : :: .: : :. . * *: :: : :. .. .. :* *:. *. . :::**...: .* :: * :.*. . .* : : :.* ::.:** ::.::*:***::.:. ..: *. * ::. **:.*:.:..:*.* *** :: **:: . . .: .*.. ** ::*:*: ::.* : *. : :: : :: : * ::* :: . : :: **:**::* :.* :::* * :::* : * .: :*: . : *:: : : * ** : :.: . : :: .: . . :. . :. : . : . :: ", "identical_positions": 73, "similar_positions": 184, "identity": "5.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100422-16", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61282-1", "uniprot_id": "PGCA_MOUSE", "id": "Q61282-1", "name": "Aggrecan core protein", "aln": "--MTTLLLVFVTLRVIAAVISEEVPDHDNSLSVSIPQPSPLKVLLGSSLTIPCYFIDPMHP---VTTAPSTAPLTPRIKWSRVSKEKEVVLLVATEGQVRVNSIYQDKVSLPNYPAIPSDATLEIQNLRSNDSGIYRCEVMHGIEDSEATLEVIVKGIVFHYRAISTRYTLDFDRAQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQGGMDMCSAGWLADRSVRYPISKARPNCGGNLLGVRTVYLHANQTGYPDPSSRYDAICYTGEDFVDIPENFFGVGGEDDITIQTVTWPDLELPLPRNVTEGEALGSVILTAKPIFDLSPTISEPGEALTLAPEVGSTAFPEAEERTGEATRPWGFPAEVTRGPDSATAFASEDLVVRVTISPGAAEVPGQPRLPGGVVFHYRPGSTRYSLTFEEAQQACMHTGAVIASPEQLQAAYEAGYEQCDAGWLQDQTVRYPIVSPRTPCVGDKDSSPGVRTYGVRPSSETYDVYCYVDKLEGEVFFATRLEQFTFQEARAFCAAQNATLASTGQLYAAWSQGLDKCYAGWLADGTLRYPIITPRPACGGDKPGVRTVYLYPNQTGLPDPLSKHHAFCFRGVSVAPSPGEEGGSTPTSPSDIEDWIVTQVGPGVDAVPLEPKTTEVP--------YFTTEPRKQTEWEPAYTPVGTSPQPGIPPTWLPTLPAAEEHTESPSASEEPSASAVP------------------------------------------------STSEEPYTSSFAVPSMTELPGSGEASGAPDLSGDFTGSGDASGRLDSSGQPSGGIESGLPSGDLDSSGLSPTVSSGLPVESGSASGDGE-VPWSHTPTVGRLPSGGESPEGSAS-----------------ASGTGDLSGLPSG------------------GEITETSTSGAEETSGLPSG------------------GDGLETSTSGVDDVSGIPTG------------------REGLETSASGVEDLSGLPSGE------------------EGSETSTSGIEDISVLPTGGESLETSASGVGDLSGLPSG------------------GESLETSASGAEDVTQLPTE------------------RGGLETSASGVEDITVLPTG------------------RESLETSASGVEDVSGLPSG------------------REGLETSASGIEDISVFPT----------------------------------------------------------------------------------------------EAEGLDTSASG----------------------------------------------------------GYVSGIPSGGDGTETSASGVEDVSGLPSG------------------GEGLETSASGVEDLG--PSTRDSLETSASGV-DVTGFPSGRGDPETSVSGVGDDFSGLPSGKEGLETSASGAEDLSGLPSGKEDLVGSASGALDFGKLPPGTLGSGQTPEVNGFPSGFSGEYSGADIGSGPSSGLPDFSGLPSGFPTVSLVDSTLVEVITATTSSELEGRGTIGISGSGEVSGLPLGELDSSADISGLPSGTELSGQASGSPDSSGETSGFFDVSGQPFGSSGVSEETSGIPEISGQPSGTPDTTATSGVTELNELSSGQPDVSGDGSGILFGSGQSSGITSVSGETSGISDLSGQPSGFPVFSGTATRTPDLASGTISGSGESSGITFVDTSFVEVTPTTFREEEGLGSVELSGFPSGETELSGTSGTVDVSEQSSGAIDSSGLTSPTPEFSGLPSGVAEVSGEFSGVETGSSLPSGAFDGSGLVSGFPTVSLVDRTLVESITQAPTAQEAGEGPSGILEFSGAHSGTPDISGELSGSLDLSTLQSGQMETSTETPSSPYFSGDFSSTTDVSGESIAATTGSGESSGLPEVTLNTSELVEGVTEPTVSQELGHGPSMTYTPRLFEASGDASASGDLGGAVTNFPGSGIEAS-VPEASSDLSAYPEAGVGVSAAPEASSKLSEFPDLHGITSAFHETDLEMTTPSTEVNSNPWTFQEGTREGSAAPEVSGESSTTSDIDTGTSGVPSATPMASGDRTEISGEWSDHTSEVNVAISSTITESEWAQPTRYPTETLQEIESPNPSYSGEETQTAETTMSLTDAPTLSSSEGSGETES-TVAD--------------------------------------QEQCEEGWTKFQGHCYRHFHDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQDYQWIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGEDCVVMIWHERGEWNDVPCNYQLPFTCKKGTVACGDPPVVEHARTLGQKKDRYEISSLVRYQCTEGFVQRHVPTIRCQPSGHWEEPRITCTDPNTYKHRLQKRSMRPTRRSRPSMAH----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07897-1", "uniprot_id": "PGCA_RAT", "id": "P07897-1", "name": "Aggrecan core protein", "aln": "--MTTLLLVFVTLRVIAAVISEEVPDHDNSLSVSIPQPSPLKALLGTSLTIPCYFIDPMHP---VTTAPSTAPLTPRIKWSRVSKEKEVVLLVATEGQVRVNSIYQDKVSLPNYPAIPSDATLEIQNLRSNDSGIYRCEVMHGIEDSEATLEVIVKGIVFHYRAISTRYTLDFDRAQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRTVGARLATTGQLYLAWQGGMDMCSAGWLADRSVRYPISKARPNCGGNLLGVRTVYLHANQTGYPDPSSRYDAICYTGEDFVDIPENFFGVGGEEDITIQTVTWPDLELPLPRNITEGEARGNVILTAKPIFDMSPTVSEPGEALTLAPEVGTTVFPEAGERTEKTTRPWGFPEEATRGPDSATAFASEDLVVRVTISPGAVEVPGQPRLPGGVVFHYRPGSTRYSLTFEEAQQACIRTGAAIASPEQLQAAYEAGYEQCDAGWLQDQTVRYPIVSPRTPCVGDKDSSPGVRTYGVRPSSETYDVYCYVDKLEGEVFFATQMEQFTFQEAQAFCAAQNATLASTGQLYAAWSQGLDKCYAGWLADGTLRYPIVNPRPACGGDKPGVRTVYLYPNQTGLPDPLSKHHAFCFRGVSVVPSPG----GTPTSPSDIEDWIVTRVEPGVDAVPLEPETTEVP--------YFTTEPEKQTEWEPAYTPVGTSPLPGIPPTWLPTVPAAEEHTESPSASQEPSASQVP------------------------------------------------STSEEPYTPSLAVPSGTELPSSGDTSGAPDLSGDFTGSTDTSGRLDSSGEPSGGSESGLPSGDLDSSGLGPTVSSGLPVESGSASGDGE-IPWSSTPTVDRLPSGGESLEGSAS-----------------ASGTGDLSGLPSG------------------GEITETSASGTEEISGLPSG------------------GDDLETSTSGIDGASVLPTG------------------RGGLETSASGVEDLSGLPSGE------------------EGSETSTSGIEDISVLPTG-ESPETSASGVGDLSGLPSG------------------GESLETSASGVEDVTQLPTE------------------RGGLETSASGIEDITVLPTG------------------RENLETSASGVEDVSGLPSG------------------KEGLETSASGIEDISVFPT----------------------------------------------------------------------------------------------EAEGLETSASG----------------------------------------------------------GYVSGIPSGEDGTETSTSGVEGVSGLPSG------------------GEGLETSASGVEDLG--LPTRDSLETSASGV-DVTGYPSGREDTETSVPGVGDDLSGLPSGQEGLETSASGAEDLGGLPSGKEDLVGSASGALDFGKLPSGTLGSGQTPEASGLPSGFSGEYSGVDIGSGPSSGLPDFSGLPSGFPTVSLVDSTLVEVITATTASELEGRGTISVSGSGEESGPPLSELDSSADISGLPSGTELSGQTSGSLDVSGETSGFFDVSGQPFGSSGTGEGTSGIPEVSGQAVRSPDTTEIS---ELSGLSSGQPDVSGEGSGILFGSGQSSGITSVSGETSGISDLSGQPSGFPVLSGTTPGTPDLASGAMSGSGDSSGITFVDTSLIEVTPTTFREEEGLGSVELSGLPSGETDLSGTSGMVDVSGQSSGAIDSSGLISPTPEFSGLPSGVAEVSGEVSGVETGSSLSSGAFDGSGLVSGFPTVSLVDRTLVESITLAPTAQEAGEGPSSILEFSGAHSGTPDISGDLSGSLDQSTWQPGWTEASTEPPSSPYFSGDFSSTTDASGESITAPTGSGETSGLPEVTLITSELVEGVTEPTVSQELGHGPSMTYTPRLFEASGEASASGDLGGPVTIFPGSGVEAS-VPEGSSDPSAYPEAGVGVSAAPEASSQLSEFPDLHGITSASRETDLEMTTPGTEVSSNPWTFQEGTREGSAAPEVSGESSTTSDIDAGTSGVPFATPMTSGDRTEISGEWSDHTSEVNVTVSTTVPESRWAQSTQHPTETLQEIGSPNPSYSGEETQTAETAKSLTDTPTLASPEGSGETES-TAAD--------------------------------------QEQCEEGWTKFQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNKNAQDYQWIGLNDRTIEGDFRWSDGHSLQFEKWRPNQPDNFFATGEDCVVMIWHERGEWNDVPCNYQLPFTCKKGTVACGEPPAVEHARTLGQKKDRYEISSLVRYQCTEGFVQRHVPTIRCQPSADWEEPRITCTDPNTYKHRLQKRTMRPTRRSRPSMAH----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16112-1", "uniprot_id": "PGCA_HUMAN", "id": "P16112-1", "name": "Aggrecan core protein", "aln": "--MTTLLWVFVTLRVITAAVTVETSDHDNSLSVSIPQPSPLRVLLGTSLTIPCYFIDPMHP---VTTAPSTAPLAPRIKWSRVSKEKEVVLLVATEGRVRVNSAYQDKVSLPNYPAIPSDATLEVQSLRSNDSGVYRCEVMHGIEDSEATLEVVVKGIVFHYRAISTRYTLDFDRAQRACLQNSAIIATPEQLQAAYEDGFHQCDAGWLADQTVRYPIHTPREGCYGDKDEFPGVRTYGIRDTNETYDVYCFAEEMEGEVFYATSPEKFTFQEAANECRRLGARLATTGQLYLAWQAGMDMCSAGWLADRSVRYPISKARPNCGGNLLGVRTVYVHANQTGYPDPSSRYDAICYTGEDFVDIPENFFGVGGEEDITVQTVTWPDMELPLPRNITEGEARGSVILTVKPIFEVSPSPLEPEEPFTFAPEIGATAFAEVENETGEATRPWGFP---TPGLGPATAFTSEDLVVQVTAVP------GQPHLPGGVVFHYRPGPTRYSLTFEEAQQACLRTGAVIASPEQLQAAYEAGYEQCDAGWLRDQTVRYPIVSPRTPCVGDKDSSPGVRTYGVRPSTETYDVYCFVDRLEGEVFFATRLEQFTFQEALEFCESHNATLATTGQLYAAWSRGLDKCYAGWLADGSLRYPIVTPRPACGGDKPGVRTVYLYPNQTGLPDPLSRHHAFCFRGISAVPSPGEEEGGTPTSPSGVEEWIVTQVVPGVAAVPVEEETTAVPSGETTAILEFTTEPENQTEWEPAYTPVGTSPLPGILPTWPPTGAATEESTEGPSATEVPSASEEPSPSEVPFPSEEPSPSEEPFPSVRPFPSVELFPSEEPFPSKEPSPSEEPSASEEPYTPSPPVPSWTELPSSGEESGAPDVSGDFTGSGDVSGHLDFSGQLSGDRASGLPSGDLDSSGLTSTVGSGLPVESGLPSGDEERIEWPSTPTVGELPSGAEILEGSASGVGDLSGLPSGEVLETSASGVGDLSGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETTAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSG-EVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETAAPGVEDISGLPSGEVLETTAPGVEEISGLPSGEVLETTAPGVDEISGLPSGEVLETTAPGVEEISGLPSGEVLETSTSAVGDLSGLPSGGEVLEISVSGVEDISGLPSGEVVETSASGIEDVSELPSGEGLETSASGVEDLSRLPSGEEVLEISASGFGDLSGLPSGGEGLETSASEVGTDLSGLPSGREGLETSASGAEDLSGLPSGKEDLVGSASGDLDLGKLPSGTLGSGQAPETSGLPSGFSGEYSGVDLGSGPPSGLPDFSGLPSGFPTVSLVDSTLVEVVTASTASELEGRGTIGISGAGEISGLPSSELDISGRASGLPSGTELSGQASGSPDVSGEIPGLFGVSGQPSGFPDTSGETSGVTELSG-------------------LSSGQPGISGEASGVLYGTSQPFGITDLSGETSGVPDLSGQPSGLPGFSGATSGVPDLVSGTTSGSGESSGITFVDTSLVEVAPTTFKEEEGLGSVELSGLPSGEADLSGKSGMVDVSGQFSGTVDSSGFTSQTPEFSGLPSGIAEVSGESSRAEIGSSLPSGAYYGSGTPSSFPTVSLVDRTLVESVTQAPTAQEAGEGPSGILELSGAHSGAPDMSGEHSGFLDLSGLQSGLIEPSGEPPGTPYFSGDFASTTNVSGESSVAMGTSGEASGLPEVTLITSEFVEGVTEPTISQELGQRPPVTHTPQLFESSGKVSTAGDISGATPVLPGSGVEVSSVPESSSETSAYPEAGFGASAAPEASREDSGSPDLSETTSAFHEANLERSS-GLGVSGSTLTFQEG--EASAAPEVSGESTTTSDVGTEAPGLPSATPTASGDRTEISGDLSGHTSQLGVVISTSIPESEWTQQTQRPAETHLEIESSSLLYSGEETHTVETATSPTDASIPASPEWKRESES-TAAAPARSCAEEPCGAGTCKETEGHVICLCPPGYTGEHCNIDQEVCEEGWNKYQGHCYRHFPDRETWVDAERRCREQQSHLSSIVTPEEQEFVNNNAQDYQWIGLNDRTIEGDFRWSDGHPMQFENWRPNQPDNFFAAGEDCVVMIWHEKGEWNDVPCNYHLPFTCKKGTVACGEPPVVEHARTFGQKKDRYEINSLVRYQCTEGFVQRHMPTIRCQPSGHWEEPQITCTDPTTYKRRLQKRSSRHPRRSRPSTAH----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TGD0-1", "uniprot_id": "A0AB32TGD0_DANRE", "id": "A0AB32TGD0-1", "name": "Aggrecan core protein", "aln": "MSLIWLLLYICTHGISGMILFGDMADQDSTLSVSIPVEQPLRPLLGGSMVIPCYFQDITLQDPGTLTSPTNAPLSQRIKWSHIHKGKISLILVATEGQVQVETEYLDRVHLVNYPMVPSDATIEISELRSHDSGTYRCEVMQGIDDNYDSVEMQIQGIVFHYRAISTRYTLTFEMAKAACIQNSAVIATPAQLQAAYDDGFHQCDAGWLSDQTVRYPIHEPREPCYGDKDNFPGVRTYGVRDVNETYDVYCFAEKMSGRVFYSMSVEKFTFADAEDQCAKLGAQLATTGQLYLAWKTGMDVCNAGWLADRSVRYPINIARPQCGGGLLGVRTVYLFPNQTGYPYPDSRYDAICYE--------------DKEDKVLIKTTPFPEIYTTTES--------------VLTVATVTSSSSDYTEQVTTEGEVRGQILTDEPFNTTSTESPLSPPLNITDVEEDIINVATAPPSLEHAIPS-----INVTAKIKGVVFHYRAESGRYAYTYEEAQDACQKLGAVIATPELLQAAYEAGLHQCSAGWLQDQTVRYPIVHPRKKCSGDSEDVPGVRSYNVRPAHEQYDVYCYMDQIKGEIFHVSSLAGFTYYEAVAHCRKLSSTLASTGELYAAWNQGFHKCSPGWLADRSVRYPVGSPDFDCGGNKTGVQTIYAQPNQTGSPHPYSRYDAYCFKANLSLG--------------------------------------------------FDEDMLNATDITMLQRPVHP-----IVP-----------------------------------------------------------------------------------------PLFVDMSGSGSGSGYASASTSGSGSDSASG-----------SASGVP----DSS---SGYISGSGIASGSASGSGQ--------------SG---------------------------DGSGFLVRYQEG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TDALMWSSASG-----------------------------------------------------------------SASEAKDGSGSGIIITSGIQSG----------------------------------------------------------------------------------------------DQESGEE---------------------SGHFAVASGLPSGLG-----------------------------------------------------SGISGSG---------------TSGFFSGEESSG------------SGFFSVS-----------------------------------------------------------------------------------------------------------------FVDTKMIDLTARAFGEQE------LSGFYTAES--------------------------------GFPSG----SGSFSGFETGSAIGFESNSAFGSGSGFETGSAIG-------FESNSASAFGSGSSSGFESSSAFG---------FGSGSASGFGSGIASGIESSPASAFGSGSASG----FGSSSAIGLESSSASGFKSVSVTGTSGYPNHPSGEVSENIQR-----------QDGEMIIFTDDEVTELTLRPTAGTEQG---RGSVEIS-------GEGSTPEPYTEDS----ISVSNSTSHESND------------------------LLPERDEKISVTMEAFDVTDKSPLITTPTN----------------IPVLTTPSSASLQMPKSTMNPSVNEAPFDPCDPNPCGQGLCSLQDGVALCQCHSGFSGENCSMLVQG---------------------------------------------CAEGWMEFMGSCYIHFDERETWTSAEQHCQELNSHLVSISSQQEQEFVKTQAQDYQWIGLNDKDVQNEFRWTDGSPLEYENWRPNQPDNYFSTGEDCVVMIWHENGQWNDVPCNYHLPFTCKSGPVTCTTPPEVQNARMLGNSKDRYPVNSFIRYQCNSGFTQRHLSVVRCLPDGQWEKPRVECIRG-IENNRLRKRSLYIRPKAVNSRTWRKVL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ** : * : : : .*:*.:****** .**: *** *:.***** * . *:*:.***: *****:: * * ::******:*:*:: * *:* * *** :*****:*:..***:*** ******:**:*. ::*: ::*************** *: *: **:****:**** ******:***********:********* *** ******:********:**.***********:*.*.***: * ***** :* ::* :**:***********: ***:*.*************. ***:***.********:..****** *.******** . *:.: ::*..:*:: . . .: ::.: : * .* *: :.: .* .: * . * * .:: :. : . . . *******. . **: *:****:** : **.**:** ******** .**.****:********* **. * **.:. ****:*.***: * *****::*:::**:*..: : **: ** .* .:***:**:*****.:*:.** .***** ::***: .* ***:*.**:*:* ***** *.* *::.*:**:. * : : *: ** . * * * .::..**. ** .. * . :** ..** **:* *** . ** : ** .**. : ** .* * * .* : ::*.* *. : : * **: **: ** . **:* **: . ..*:***:. .:**:* **: ** * ** .*:*.** ****.:::::. :* *:* ***: :.*: *:*** **. * * **:: : . * *.* * * :. : :*. *.*.*. :* *.*.. * . * .* . ..*.:.: **. :. *.* . *..:**: .*:: :. . .. :*::: : : . :.* . * :* * . ..* : * * .::**. : * : .*: :*:: ** . : :.* : : * *. :. : * :.: .. . .: * *: . : . . .*: : : : : * * . * *** :: * ** ** :****..**::*:* :*** ** : :*****:.:***********: ::.:***:** .:::*:********:*::***********.*:********:******.*.*:* ** *::** :*:.**** :.*::****..**.***:..:** *...**:*:: * :.**:**: :: * : ", "identical_positions": 601, "similar_positions": 387, "identity": "23.37%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100422-17", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KA38-1", "uniprot_id": "A0A0G2KA38_RAT", "id": "A0A0G2KA38-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------MMGLPEGLRSMADSPEVVAMDCEMVGLGPQ-RVSGLARCSIVNVHSAVLYDKYIQPEGEITDYRTQVSGITPQHMARATPFAEARLEILQLLKGKLVVGHDLKHDFSALKEDMRKYTIYDTSTDMLLWHEAKLHCYSRVSLRLLCKRLLHKSIQN-------------------------------------------------------NWRGHCSVEDARATMELY---------------KISQRLRAQRG---LPCLGTSA----------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JL16-1", "uniprot_id": "ISG20_MOUSE", "id": "Q9JL16-1", "name": "Interferon-stimulated gene 20 kDa protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------MAGIPEVVAMDCEMVGLGPQ-RVSGLARCSIVNIHGAVLYDKYIRPEGEITDYRTQVSGVTPQHMVRATPFGEARLEILQLLKGKLVVGHDLKHDFNALKEDMSKYTIYDTSTDRLLWHEAKLQYYSRVSLRLLCKRLLHKNIQVLPGSLLGVGGCILPGTDILHLLLYVGMVRIADLRLLTPFLPPSCLACPLLPESLASARSHAVISALSSSSHLLTPLPNPSQGPQGHVDRLSGQLQDWGGSPLAPALPVSAEQLAGPLLCGRCQGHNGALQNLSATQSPARAALPWDVRLNFILIQG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96AZ6-1", "uniprot_id": "ISG20_HUMAN", "id": "Q96AZ6-1", "name": "Interferon-stimulated gene 20 kDa protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------MAGSREVVAMDCEMVGLGPH-RESGLARCSLVNVHGAVLYDKFIRPEGEITDYRTRVSGVTPQHMVGATPFAVARLEILQLLKGKLVVGHDLKHDFQALKEDMSGYTIYDTSTDRLLWREAKLDHCRRVSLRVLSERLLHKSIQN-------------------------------------------------------SLLGHSSVEDARATMELY---------------QISQRIRARRG---LPRLAVSD----------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RN63-1", "uniprot_id": "A0A8M1RN63_DANRE", "id": "A0A8M1RN63-1", "name": "", "aln": "MSTLLWKHLNSNGVEQNIHTPASVKETSSISHQKKKCKRKKNIKKKNPAIHDTSFEQNRGQKRKLLDNKTECIKNGSTSDFVSEESNNMQFKRPRLTHHTLPGESWEVDSGFSSESSPPTSGRSSPCLRIDHSRIVAMDCEMVGTGPGGRRSEVARCSIVDYYGNVVYDSYILPQDPVTDYRTRWSGIRSHHLRQAVPFEHAQNEILKILKGKIIVGHALYHDLNVLYISVQPHMIRDTCSCVLLRQLYDVNQNCNISLKKLAQKLLNRTIQVD-------------------------------------------------------RQGHCSVEDALSALDLY-------------------KLVEDQWENNILCQDSNAEQSQ--------QFSNNSLKHYLQDQYWPENMMDCSL---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:********* ** * * :****:*: :. *:**.:* *:. :*****: **: .:*: *.** *: ***::****::*** * **:..* .: : * **.: ** : .:. .:**: *.::**::.** .*. :. :: .* :: . ", "identical_positions": 63, "similar_positions": 56, "identity": "14.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100422-19", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NZG7-1", "uniprot_id": "NINJ2_HUMAN", "id": "Q9NZG7-1", "name": "Ninjurin-2", "aln": "MESARENIDLQP-GSSDPRSQPINLNHYATKKSVAESMLDVALFMSNAMRLKAVLEQGPSSHYYTTLVTLISLSLLLQVVIGVLLVVIARLNLNEVEKQWRLNQLNNAATILVFFTVVINVFITAFGAHKTGFLAARASRNPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JL89-1", "uniprot_id": "NINJ2_MOUSE", "id": "Q9JL89-1", "name": "Ninjurin-2", "aln": "MESDRETIHLQHRHSMRGGNQRIDLNFYATKKSVAESMLDVALFMSNAMRLKSVLQQGPFAEYYTTLVTLIIVSLLLQVVISLLLVFIAILNLNEVENQRHLNKLNNAATILVFITVVINIFITAFGAHHAASMAARTSSNPI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FE82-1", "uniprot_id": "E7FE82_DANRE", "id": "E7FE82-1", "name": "", "aln": "MPAATGRTDPQP-------TEPLNMNHYATKKSVAESMLDVALLMANASQLKAVLEQGPEFRYYLTVIILIGASLFFQVLAGALFVNMARKNLNNVANQRKLDIMNNVATGLVFLTVIINIFITAFGVQKTGLYPKQ------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . * .: :::*.****************:*:** :**:**:*** .** *:: ** **::**: . *:* :* ***:* :* :*: :**.** ***:**:**:******.:::. . : ", "identical_positions": 64, "similar_positions": 38, "identity": "44.76%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100422-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IWQ3-1", "uniprot_id": "BRSK2_HUMAN", "id": "Q8IWQ3-1", "name": "Serine/threonine-protein kinase BRSK2", "aln": "-------------------------------------------------------------MTSTGKDGG-AQHAQYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNRE------------------------------------KLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDN--LRQLLEKVKRGVFHMP--HFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWY--------------------IGGKNEPEPEQPIPRKVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNKLLQDLLSEEENQEKMIYFLLLDRKERY----PSQEDEDLPPR------NEIDPPRKRVDSPMLN-------------------------------RHGKRRPERKSMEVLSVTDGGSPVPARRAIEMAQHGQ-----------------------RSRSISGASSGLSTSPLSSPR--------------------------------------------------------------------------------------------------------------------------------------------------------------VTPHPSPRGSPLPTPKGTPVHTPKESPAGTPN-------------------------------------------------------------------------------PTPPSSPSVGGVP-----------WRARLNSIKNSFLGSPRFHRRKLQVPTPEEMSNLTPESSPELAKKSWFGNFISLEKEEQIFVVIKD-----KPLSSIKADIVHAFLSIPSLSHSVISQTSFRAEYKATG-------------------------------------------------------------------------------------GPAVFQKPVKFQVDITYTEGGEAQKENGIYSVTFTLLSGPSRRFKRVVETIQAQLLSTHDP--------------------PAAQHLSDTTNCMEMMTGRLSKCGSPLSNFFDVIKQLFSDE-----KNGQAAQAPSTPAKRSAHGPLGDSAAAGPGPGGDAEYPTG--KDTAKMGPPTARREQP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q69Z98-1", "uniprot_id": "BRSK2_MOUSE", "id": "Q69Z98-1", "name": "Serine/threonine-protein kinase BRSK2", "aln": "-------------------------------------------------------------MTSTGKDGGGAQHAQYVGPYRLEKTLGKGQTGLVKLGIHCVTCQKVAIKIVNRE------------------------------------KLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDERNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDN--LRQLLEKVKRGVFHMP--HFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWY--------------------IGGKNEPEPEQPIPRKVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNKLLQDLLSEEENQEKMIYFLLLDRKERY----PSHEDEDLPPR------NEIDPPRKRVDSPMLN-------------------------------RHGKRRPERKSMEVLSVTDGGSPVPARRAIEMAQHGQ-----------------------RSRSISGASSGLSTSPLSSPR--------------------------------------------------------------------------------------------------------------------------------------------------------------VTPHPSPRGSPLPTPKGTPVHTPKESPAGTPN-------------------------------------------------------------------------------PTPPSSPSVGGVP-----------WRTRLNSIKNSFLGSPRFHRRKLQVPTPEEMSNLTPESSPELAKKSWFGNFINLEKEEQIFVVIKD-----KPLSSIKADIVHAFLSIPSLSHSVISQTSFRAEYKATG-------------------------------------------------------------------------------------GPAVFQKPVKFQVDITYTEGGEAQKENGIYSVTFTLLSGPSRRFKRVVETIQAQLLSTHDQ--------------------PSAQHLSDTTNCMEVMTGRLSKCGTPLSNFFDVIKQLFSDE-----KNGQAAQAPSTPAKRSAHGPLGDSAAAGPG--GDTEYPMG--KDMAKMGPPAARREQP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M6YYI9-1", "uniprot_id": "A0A8M6YYI9_DANRE", "id": "A0A8M6YYI9-1", "name": "", "aln": "-------------------------------------------------------------MSLSGKENSTTPHANYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNRE------------------------------------KLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDN--LRNLLEKVKLGVFHMP--HFIPPECQNLLRGMIEVDSGKRLTLELIQKHMWY--------------------IGGKNEPEPEQPVPRKVAIRSVPSSEDIDPDVLESMHSLGCFRDKNKLMKDLLSDDENQEKMIYFLLLDRKERY----PSQEDQNLPPR------NDIDPPRKRVDSPMLN-------------------------------RHGKRRPERKSMEVLSVTDGGSPVPARRAIDMTQHGQSKSTFSKSLDISDAKHKAKSKEERSRSISGASSGLSTSPLSSPRPVRKFCVPPQSSELLLSPSSSIIDSLKPNSDQNMAKTSNSLTPNSISESLLPYPKTQTLPAKPKDKPLQSARSNPL--PESEPEHISTAKSEPSTPCQPQAPCIPGSPLVRRATPASIIPPQLSVPFRPAVPLSPIRLHHFHPVPGSDHTTKSIPTIQVTPHPSPRSSPIPTPKGTPIHTPKNSPAGTPT-------------------------------------------------------------------------------PTPPPSPSIGGMP-----------WKTRLNSFKNSFLGSPRFHRRKLQVPTQEEMSSLTPESSPELAKKSWFGNFINLEKEEQIFVVIKD-----KPLSSIKADIVHAFLSIPSLSHSVISQTSFRAEYKSTA-------------------------------------------------------------------------------------GPTVFQKPVKFQVDITYTESTAANKENGIYSVTFTLLSGPSRRFKRVVETIQAQLLSTHDQ--------------------PGVQQLS----------------GSPLSNFFDVIKQLFSDE-----KNSQVPVPPGTPNRHPPNARRHDPQPN------DSKCPPGNPRDNAKLVASAETQEQL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZML2-1", "uniprot_id": "BRSK2_RAT", "id": "D3ZML2-1", "name": "Serine/threonine-protein kinase BRSK2", "aln": "-------------------------------------------------------------MTSTGKDGGGAQHAQYVGPYRLEKTLGKGQTGLVKLGIHCVTCQKVAIKIVNRE------------------------------------KLSESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDERNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDDN--LRQLLEKVKRGVFHMP--HFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWY--------------------IGGKNEPEPEQPIPRKVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNKLLQDLLSEEENQEKMIYFLLLDRKERY----PSHEDEDLPPR------NEIDPPRKRVDSPMLN-------------------------------RHGKRRPERKSMEVLSVTDGGSPVPARRAIEMAQHGQ-----------------------RSRSISGASSGLSTSPLSSPR--------------------------------------------------------------------------------------------------------------------------------------------------------------VTPHPSPRGSPLPTPKGTPVHTPKESPAGTPN-------------------------------------------------------------------------------PTPPSSPSVGGVP-----------WRTRLNSIKNSFLGSPRFHRRKLQVPTPEEMSNLTPESSPELGHLQLFGNPVSKVRSVAMELVILV-----QTLAYTSFRLLGTFLPVRYLRHSVLSRPPERARLVLRG-------------------------------------------------------------------------------------APCTHMGPVWNMVGMAYTQNPPIMGETGVYGSQWVMSSAPSKHYTSLGLSVPSPSCSLSPS--------------------LFPFCAPDTTNCMEVMTGRLSKCGTPLSNFFDVIKQLFSDE-----KNGQAAQAPSTPAKRSAHGPLGDSAAAGPG--GDTEYPMG--KDMAKMGPPAARREQP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VUV4-1", "uniprot_id": "Q9VUV4_DROME", "id": "Q9VUV4-1", "name": "non-specific serine/threonine protein kinase", "aln": "---------------------------------------------------------------MQKENNVTAENCQFVGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINRE------------------------------------KLSESVLMKVEREIAIMKLIDHPHVLGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNN-IKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPFDDDN--LRQLLEKVKRGVFHIP--HFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWVT-------------------AGGKGELELELPMMEVVQTHVIPTATAVDPDVLNAICSLGCFKEKEKLIQELLSSSHNTEKVIYFLLLERKRRR----PALEDDDEIAQKSRSELDAVDPPRKRLDTCRINGTNAPSYGQISEGSPLTPRRQAFNFRSYSSTRNHQRRSPTTVTSSVRSSSYHSPTRCNSPMSSAQQQANAISRPSSPAAG-----TRHSTYGDRDRSGHHSSVSRTPSHSSQKSIEGDVVVVREPRIERRDS----------------------------------------------------------------------------------------------------------LRQERGGGSPRDRGDCGIPPGSPGGNSSGSTSASPSVHHRANSGPTIAISMFHDPDSNSVVNPN-------------------------------------------------------------------------------GSPMMNNSSPGMPGSPCNTPGGQLWKTRLTNIKNSFLGSPRFHRRKMQVSADEVH--LTPESSPELTKRSWFGNLITTEKDETFTILVKG-----KPIATVKAHLIHAFLSMAELSHSVVSPTSFRVEYKRNGN------------------------------------------------------------------------------------GPVMFQRHVKFQVDISAICK-QGDIADMLFALTFTLLSGNIRRFRRICEHIQSQVCSKRFPGP------------------SSPPTVTSVTQAVSESSSCGSVSSERLSYKRQVIENDMENDSIFSYKSGNGRRASTTNNNNANPVDIPGSPIAVRSNSETAEHERNRELQSERQATTMSGSAIA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P34244-1", "uniprot_id": "HSL1_YEAST", "id": "P34244-1", "name": "Probable serine/threonine-protein kinase HSL1", "aln": "MTGHVSKTSHVPKGRPSSLAKKAAKRAMAKVNSNPKRASGHLERVVQSVNDATKRLSQPDSTVSVATKSSKRKSRDTVGPWKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDDN--IKKLLLKVQSGKYQMP--SNLSSEARDLISKILVIDPEKRITTQEILKHPLIKKYDDLPVNKVLRKMRKDNMARGKSNSDLHLLNNVSPSIVTLHSKGEIDESILRSLQILWHGVSRELITAKLLQKPMSEEKLFYSLLLQYKQRHSISLSSSSENKKSATESSVNEPRIEYASKTANNTGLRSENNDVKTLHSLEIHSEDTSTVNQNNAITGVNTEINAPVLAQKSQFSINTLSQPESDKAEAEAVTLPPAIPIFNASSSRIFRNSYTSISSRSRRSLRLSNSRLSLSASTSRETVHDNEMPLPQLPKSPSRYSLSRRAIHASPSTKSIHKSLSRKNIAATVAARRTLQNSASKRSLYSLQSISKRSLNLNDLLVFDDPLPSKKPASENVNKSEPHSLESDSDFEILCDQILFGNALDRILEEEEDNEKERDTQRQRQNDTKSSADTFTISGVSTNKENEGPEYPTKIEKNQFNMSYKPSENMSGLSSFPIFEKENTLSSSYLEEQKPKRAALSDITNSFNKMNKQEGMRIEKKIQREQLQKKNDRPSPLKPIQHQELRVNSLPNDQGKPSLSLDPRRNISQPVNSKVESLLQGLKFKKEPASHWTHERGSLFMSEHVEDEKPVKASDVSIESSYVPLTTVATSSRDPSVLAESSTIQKPMLSLPSSFLNTSMTFKNLSQILADDGDDKHLSVPQNQSRSVAMSHPLRKQSAKISLTPRSNLNANLSVKRNQGSPGSYLSNDLDGISDMTFAMEIPTNTFTAQAIQLMNNDTDNNKINTSPKASSFTKEKVIKSAAYISKEKEPDNSDTNYIPDYTIPNTYDEKAINIFEDAPSDEGSLNTSSSESDSRASVHRKAVSIDTMATTNVLTPATNVRVSLYWNNNSSGIPRETTEEILSKLRLSPENPSNTHMQKRFSSTRGSRDSNALGISQSLQSMFKDLEEDQDGHTSQADILESSMSYSKRRPSEESVNPKQRVTMLFDEEEEESKKVGGGKIKEEHTKLDNKISEESSQLVLPVVEKKENANNTENNYSKIPKPSTIKVTKDTAMESNTQTHTKKPILKSVQNVEVEEAPSSDKKNWFVKLFQNFSSHNNATKASKNHVTNISFDDAHMLTLNEFNKNSIDYQLKNLDHKFGRKVVEYDCKFVKGNFKFKIKITSTPNASTVITVKKRSKHSNTSSNKAFEKFNDDVERVIRNAGRS--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P25389-1", "uniprot_id": "KCC4_YEAST", "id": "P25389-1", "name": "Probable serine/threonine-protein kinase KCC4", "aln": "------------------------------------------------------------MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFN---------------------------NNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYN-IKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKD------------SKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDS----VRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRS---------------------IQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTN-----------------------------------------------------------------------------------------------------------------LIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFG----------------------------------------------------------------------------SEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRS--KFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRME-------------------------------------------------------------------------------------PRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRS------------------EDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDN---------------------------------------------------------------DTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTG-----STKTLTKLATEIQIILQKEGVLDK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :**::* :*** *.:* *:*. : : .*:*:: :. : .. :****.*:**:.*.:*: * :*:*.:. ***:**:.. ****: **.:* *. :** : *:**: .:.:**: .* ************. . *:*******:*: .:*:*********.**:: * *.* :******::*:***.* ***:::* ::.** **: * :.:* :. :.:.*: :: ::. :*:. * * . : . : :* .:* : * : : .* .. . **::* ** * .:.. . . . .. :. . . . . . .. .. . :* . . .. . . . . . . : :: . .* . . . . : .: : . : . . . . : . :::.. . : . . ", "identical_positions": 118, "similar_positions": 171, "identity": "7.74%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100422-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IWQ3-1", "uniprot_id": "BRSK2_HUMAN", "id": "Q8IWQ3-1", "name": "Serine/threonine-protein kinase BRSK2", "aln": "-------------------------------------------------------------MTSTGKDGG-AQHAQYVGPYRLEKTLGKGQTGLVKLGVHCVTCQKVAIKIVNREKLSES------------------------------------VLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDD--NLRQLLEKVKRGVFHMP--HFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWY--------------------IGGKNEPEPEQPIPRKVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNKLLQDLLSEEENQEKMIYFLLLDRKERYPSQEDEDLPPR---------------NEIDPPRKRVDSPMLN--------------------------------------------------------------------RHGKRRPERKSMEVLSVTDGGS------------------------------PVPARRAIEMAQHGQ-----------------------RSRSISGASSGLSTSPLSSPR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------VTPHPSPRGSPLPTPKGTPVHTPKESPAGTPNPTPPSSPSVGGVP--------------------WRARLNSIKNS-FLGSPRFHRRKLQVPTPEEMSNLTPESSPELAKKSWFGN-------------------------------------------------------------------------FISLEKEEQIFVVIKDKPLSSIKADIVHAFLSIPSLSHSVISQTSFRAEYKATG-GPAVFQKPVKFQVDITYTEGGEAQKENG------------------------------------------------------------------------------------------------------IYSVTFTLLSGPSR------------------------RFKRVVETIQAQLLSTHDP--PAAQHLSDTTNCMEMMTGRLSKCGSPLSNFFDVIKQLFSDE-----KNGQAAQAPSTPAKRSAHGPLGDSAAAGPGPG-------------------------------------GDAEYPTGKDTAKMGPPTARREQP-----------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q69Z98-1", "uniprot_id": "BRSK2_MOUSE", "id": "Q69Z98-1", "name": "Serine/threonine-protein kinase BRSK2", "aln": "-------------------------------------------------------------MTSTGKDGGGAQHAQYVGPYRLEKTLGKGQTGLVKLGIHCVTCQKVAIKIVNREKLSES------------------------------------VLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDERNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDD--NLRQLLEKVKRGVFHMP--HFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWY--------------------IGGKNEPEPEQPIPRKVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNKLLQDLLSEEENQEKMIYFLLLDRKERYPSHEDEDLPPR---------------NEIDPPRKRVDSPMLN--------------------------------------------------------------------RHGKRRPERKSMEVLSVTDGGS------------------------------PVPARRAIEMAQHGQ-----------------------RSRSISGASSGLSTSPLSSPR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------VTPHPSPRGSPLPTPKGTPVHTPKESPAGTPNPTPPSSPSVGGVP--------------------WRTRLNSIKNS-FLGSPRFHRRKLQVPTPEEMSNLTPESSPELAKKSWFGN-------------------------------------------------------------------------FINLEKEEQIFVVIKDKPLSSIKADIVHAFLSIPSLSHSVISQTSFRAEYKATG-GPAVFQKPVKFQVDITYTEGGEAQKENG------------------------------------------------------------------------------------------------------IYSVTFTLLSGPSR------------------------RFKRVVETIQAQLLSTHDQ--PSAQHLSDTTNCMEVMTGRLSKCGTPLSNFFDVIKQLFSDE-----KNGQAAQAPSTPAKRSAHGPLGDSAAAGPG---------------------------------------GDTEYPMGKDMAKMGPPAARREQP-----------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3B1F0-1", "uniprot_id": "A0A8M3B1F0_DANRE", "id": "A0A8M3B1F0-1", "name": "", "aln": "-------------------------------------------------------------MSSSGKDNSSQQHANYVGPYRLEKTLGKGQTGLVKLGIHCVTCQKVAIKIVNREKLSES------------------------------------VLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDD--NLRNLLEKVKLGVFHMP--HFIPPDCQNLLRGMIEVDATKRLTLEQIQKHTWY--------------------IGGKNEPEPEQPVPRKVAIRTLPSTEDIDPDVLESMHSLGCFRDKNKLMKDLLSDDDNQEKMIYFLLLDRKERYPSHEDQNLPPR---------------NEIDPPRKRVDSPLLT--------------------------------------------------------------------RHNKRRPERKSMEVLSVTEGGS------------------------------PVPVRRAIDMAQHGQSKSVFSKSLDISDANPILQSKEERSRSISGASSGLSTSPLSSPRPMRR-----------FAVPPQSSDLTYSPNHSPTHAPVARLNGTGPHSPKIFLPKTAADQLNNKTQTLPAKPKVADKPLQATRSNPLPNSTPVPPVAKSEPSTPCQP--------LPPQIPGSPKIRRPPLTVPPKLSVPLSPLSPIRLHHLHPLAGTDHNGKSIPTIQVTPHPSPRGSPLPTPKGTPVHTPKESPAGTPSPTPPPSPSIGGMP--------------------WRTRLNSIKNS-FLGSPRFHRRKLQVPTQEEMSSLTPESSPELAKKSWFGN-------------------------------------------------------------------------FINLEKEEQIFVVIRDKPLSSIKADIVHAFLSIPSLSHSVVSQTSFRAEYKSTA-GPTVFQKPVKFQVDITYTESMAATKENG------------------------------------------------------------------------------------------------------IYSVTFTLLSGPSR------------------------RFKRVVETIQAQLLSTHDQ--PGVQQLS----------------GSPLSNFFDVIKQLFSDE-----KNGQVSHPPGTPKHANSK-----RHEPEPN----------------------------------------DSKCPSGQDKAKMAPSVGTQEQP-----------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZML2-1", "uniprot_id": "BRSK2_RAT", "id": "D3ZML2-1", "name": "Serine/threonine-protein kinase BRSK2", "aln": "-------------------------------------------------------------MTSTGKDGGGAQHAQYVGPYRLEKTLGKGQTGLVKLGIHCVTCQKVAIKIVNREKLSES------------------------------------VLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDERNN-IRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGALPFDDD--NLRQLLEKVKRGVFHMP--HFIPPDCQSLLRGMIEVDAARRLTLEHIQKHIWY--------------------IGGKNEPEPEQPIPRKVQIRSLPSLEDIDPDVLDSMHSLGCFRDRNKLLQDLLSEEENQEKMIYFLLLDRKERYPSHEDEDLPPR---------------NEIDPPRKRVDSPMLN--------------------------------------------------------------------RHGKRRPERKSMEVLSVTDGGS------------------------------PVPARRAIEMAQHGQ-----------------------RSRSISGASSGLSTSPLSSPR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------VTPHPSPRGSPLPTPKGTPVHTPKESPAGTPNPTPPSSPSVGGVP--------------------WRTRLNSIKNS-FLGSPRFHRRKLQVPTPEEMSNLTPESSPELGHLQLFGN-------------------------------------------------------------------------PVSKVRSVAMELVILVQTLAYTSFRLLGTFLPVRYLRHSVLSRPPERARLVLRG-APCTHMGPVWNMVGMAYTQNPPIMGETG------------------------------------------------------------------------------------------------------VYGSQWVMSSAPSK------------------------HYTSLGLSVPSPSCSLSPS--LFPFCAPDTTNCMEVMTGRLSKCGTPLSNFFDVIKQLFSDE-----KNGQAAQAPSTPAKRSAHGPLGDSAAAGPG---------------------------------------GDTEYPMGKDMAKMGPPAARREQP-----------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9VUV4-1", "uniprot_id": "Q9VUV4_DROME", "id": "Q9VUV4-1", "name": "non-specific serine/threonine protein kinase", "aln": "---------------------------------------------------------------MQKENNVTAENCQFVGPYRLEKTLGKGQTGLVKLGVHCVIGKKVAIKIINREKLSES------------------------------------VLMKVEREIAIMKLIDHPHVLGLSDVYENKKYLYLILEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNN-IKIADFGMASLQPAGSMLETSCGSPHYACPEVIRGEKYDGRKADVWSCGVILYALLVGALPFDDD--NLRQLLEKVKRGVFHIP--HFVPPDCQSLLRGMIEVNPDRRLTLAEINRHPWVT-------------------AGGKGELELELPMMEVVQTHVIPTATAVDPDVLNAICSLGCFKEKEKLIQELLSSSHNTEKVIYFLLLERKRRRPALEDDDEIAQKSRSEL---------DAVDPPRKRLDTCRINGTNAPSYGQISEGSPLTPRRQAFN-------------------------------------FRSYSSTRNHQRRSPTTVTSSVRSSSYHS------------------------------PTRCNSPMSSAQQQANAISRPSSPAAG-----TRHSTYGDRDRSGHHSSVSRTPSHSSQK---------------------------------------------------------------------------------------------------------------------SIEGDVVVVREPRIERRDSLRQERGGGSPRDRGDCGIPPGSPGGNSSGSTSASPSVHHRANSGPTIAISMFHDPDSNSVVNPNGSPMMNNSSPGMPGSPC---------NTPGGQLWKTRLTNIKNS-FLGSPRFHRRKMQVSADEVH--LTPESSPELTKRSWFGN-------------------------------------------------------------------------LITTEKDETFTILVKGKPIATVKAHLIHAFLSMAELSHSVVSPTSFRVEYKRNGNGPVMFQRHVKFQVDISAICK-QGDIADM------------------------------------------------------------------------------------------------------LFALTFTLLSGNIR------------------------RFRRICEHIQSQVCSKRFPGPSSPPTVTSVTQAVSESSSCGSVSSERLSYKRQVIENDMENDSIFSYKSGNGRRASTTNNNNANPVDIPGSPIAVRSNS-------------------------------------ETAEHERNRELQSERQATTMSGSAIA---------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12263-1", "uniprot_id": "GIN4_YEAST", "id": "Q12263-1", "name": "Serine/threonine-protein kinase GIN4", "aln": "--------------------------------------------------------------MAINGNSIPAIKDNTIGPWKLGETLGLGSTGKVQLARNGSTGQEAAVKVISKAVFNTGNVSGTSIV---------------------GSTTPDALPYGIEREIIIMKLLNHPNVLRLYDVWETNTDLYLVLEYAEKGELFNLLVERGPLPEHEAIRFFRQIIIGVSYCHALGIVHRDLKPENLLLDHKYN-IKIADFGMAALETEGKLLETSCGSPHYAAPEIVSGIPYQGFASDVWSCGVILFALLTGRLPFDEEDGNIRTLLLKVQKGEFEMPSDDEISREAQDLIRKILTVDPERRIKTRDILKHPLLQKYPSIRD------------SKSIRGLPREDTYLTPLSESN----SSIDATILQNLVILWHGRDPEGIKEKLREPGANAEKTLYALLYRFKCDTQKELIKQQQVKKRQSISSVSVSPSKKVSTTPQRRRNRES---------------------------------------------------------------------LISVTSSRKKPISFNKFTASSASSSNLTTPGSSKRLSKNFSSKKKLSTIVNQSSPTPASRNKRASVINVEKNQKRASIFSTTK-KNKRSS--RSIKRMSLIPSMKRESVTTKLMSTY-----------AKLAEDDDWEYIEKETKRTSSNFATLIDEIFEYEKYEQIRKEKEELERKVREAKAREELERRRRKQEEKERARKLLEKEDLKRK-------------------QEELKKQIEIDISDLEQELSKHKEEKLDGNIRSISAPMENEEKNINHLEVDIDNILR-RRNFSLQTRPVSRLDPGIMFSSPTEEVSPVEPKRTENER----------------LTTEKKILETIRRSKFLGSSFNIDKELKLSKMEYPSIIAPQRLSEERVVSDSNDGYESLILPKDGNGVSQLKDSTATTA----------------------------------------PVSDGRLRKISEIRVPQFTRKSRHFSESNKRLSVLSMYSTKESFTNLVDILKNGNLDVNNQQSQRIPTPRSADDSEFLFETVNEEAEYTGNSSNDERLYDVGDSTIKDKS-----------------------------------------------------------------------------------ALKLNFADRFNGSNEAKQTDNLHLPILPPLNGDNELRKQNSQEGDQAHPKIKSMIPESGSSSHTEKEEENEEKEEKKPEQHKQEEDQEKREKVVDDMEPPLNKSVQKIREKNAGSQAKDHSKDHLKEHKQDKNTAIG----------------------------------NGSFFRKFSKSSDKTMELYAKISAKQLFNGLEKLLRGWTQYGLKNIKSHPNNLTLTGKLSSDNIFSLRSTLFEVNIYPRGK-MSVVQFKKVS-----GSFKAVKKLVNEVENVLNKEGVLQK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P25389-1", "uniprot_id": "KCC4_YEAST", "id": "P25389-1", "name": "Probable serine/threonine-protein kinase KCC4", "aln": "------------------------------------------------------------MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNN---NGN------------------------HSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYN-IKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKD------------SKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSS---TLSSSSSLLLNNRS---------------------------------------------------------------------IQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTD------------------SSPIPLRSSKRITHINVASANTQATPSGVPN-PHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNF-----------TNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKR------------QSVNAQKINEDE-------------------------------FGSEVSDGMKELKKINDK--------VSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLT---PVTETLPNNLKEKTALL----------------QDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSE----LAP--IEESPIVSTTPLIYNDRMEP----------------------------------------------------------------RRISDVEVPHFTRKSKHFTTANNRRSVLSLY-AKDSIKDLNEFLIKEDPDLPPQGSTDNES-RSEDPEIAESITDSRNIQYDEDDSKD------GDNVNNDN-------------------------------------------------------------------------------------ILSDFPQGVGISQEYDMKD---------------KNPNQSPISKSAEPTLVVKLP--SLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTE--SEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKK----------------------------PPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKT-----GSTKTLTKLATEIQIILQKEGVLDK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P34244-1", "uniprot_id": "HSL1_YEAST", "id": "P34244-1", "name": "Probable serine/threonine-protein kinase HSL1", "aln": "MTGHVSKTSHVPKGRPSSLAKKAAKRAMAKVNSNPKRASGHLERVVQSVNDATKRLSQPDSTVSVATKSSKRKSRDTVGPWKLGKTLGKGSSGRVRLAKNMETGQLAAIKIVPKKKAFVHCSNNGTVPNSYSSSMVTSNVSSPSIASREHSNHSQTNPYGIEREIVIMKLISHTNVMALFEVWENKSELYLVLEYVDGGELFDYLVSKGKLPEREAIHYFKQIVEGVSYCHSFNICHRDLKPENLLLDKKNRRIKIADFGMAALELPNKLLKTSCGSPHYASPEIVMGRPYHGGPSDVWSCGIVLFALLTGHLPFNDD--NIKKLLLKVQSGKYQMP--SNLSSEARDLISKILVIDPEKRITTQEILKHPLIKKYDDLPVNKVLRKMRKDNMARGKSNSDLHLLNNVSPSIVTLHSKGEIDESILRSLQILWHGVSRELITAKLLQKPMSEEKLFYSLLLQYKQRHSISLSSSSENKKSATESSVNEPRIEYASKTANNTGLRSENNDVKTLHSLEIHSEDTSTVNQNNAITGVNTEINAPVLAQKSQFSINTLSQPESDKAEAEAVTLPPAIPIFNASSSRIFRNSYTSISSRSRRSLRLSNSRLSLSASTSRETVHDNEMPLPQLPKSPSRYSLSRRAIHASPSTKSIHKSLSRKNIAATVAARRTLQNSASKRSLYSLQSISKRSLNLNDLLVFDDPLPSKKPASENVNKSEPHSLESDSDFEILCDQILFGNALDRILEEEEDNEKERDTQRQRQNDTKSSADTFTISGVSTNKENEGPEYPTKIEKNQFNMSYKPSENMSGLSSFPIFEKENTLSSSYLEEQKPKRAALSDITNSFNKMNKQEGMRIEKKIQREQLQKKNDRPSPLKPIQHQELRVNSLPNDQGKPSLSLDPRRNISQPVNSKVESLLQGLKFKKEPASHWTHERGSLFMSEHVEDEKPVKASDVSIESSYVPLTTVATSSRDPSVLAESSTIQKPMLSLPSSFLNTSMTFKNLSQILADDGDDKHLSVPQNQSRSVAMSHPLRKQSAKISLTPRSNLNANLSVKRNQGSPGSYLSNDLDGISDMTFAMEIPTNTFTAQAIQLMNNDTDNNKINTSPKASSFTKEKVIKSAAYISKEKEPDNSDTNYIPDYTIPNTYDEKAINIFEDAPSDEGSLNTSSSESDSRASVHRKAVSIDTMATTNVLTPATNVRVSLYWNNNSSGIPRETTEEILSKLRLSPENPSNTHMQKRFSSTRGSRDSNALGISQSLQSMFKDLEEDQDGHTSQADILESSMSYSKRRPSEESVNPKQRVTMLFDEEEEESKKVGGGKIKEEHTKLDNKISEESSQLVLPVVEKKENANNTENNYSKIPKPSTIKVTKDTAMESNTQTHTKKPILKSVQNVEVEEAPSSDKKNWFVKLFQNFSSHNNATKASKNHVTNISFDDAHMLTLNEFNKNSIDYQLKNLDHKFGRKVVEYDCKFVKGNFKFKIKITSTPNASTVITVKKRSKHSNTSSNKAFEKFNDDVERVIRNAGRS--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :**::* :*** *.:* *:*. : : .*:*:: : :**** *:**:.*.:*: * :*:*.:. ***:**:.. ****: **.:* *. :** . *:**: .:.:**: .* ************ . *:*******:*: .:*:*********.**:: * *.* :******::*:***.* ***::: *:: ** **: * :.:* :. :.:.*: :: ::. :*:. .* * . . :* :* : * : : .* . . ** :* ** * .. : . * . * . . . : : . . . : * *:.. :. . .* . :. . . . : : : : :. . : ", "identical_positions": 121, "similar_positions": 133, "identity": "7.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100422-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A750-1", "uniprot_id": "D4A750_RAT", "id": "D4A750-1", "name": "Beta-1,4-N-acetylgalactosaminyltransferase", "aln": "MPWFPVKKVRKQMKLLLLLLLLTCAAWLTYVHRSLVRPGRALRQRLGYGRDGEKLTGVTDS---RGVRVASSTQRAEDSSESHEEE--QAPEGRGPNMLFPGGARKPPPLNLTHQTPPWR---------EEFKGQVNLHVFEDWCGGAVGHLRRNLHFPLFPHTRTTVTKLAVSPKWKNYGLRIFGFIHPARDGDVQFSVASDDNSEFWLSLDESPAAAQLIAFVGKTGSEWTAPGEFTKFSSQVSKPRRLMASRRYYFELLHKQDDKGSDHVEVGWRAFLPGLKFEIIGSAHISLYTDESSLKMDHVAHVPQSPASHVGGYPA---QEEPSADMLHPDPRDTFFLTPRMEPLSLENVLEPCAYAPTYVLKDFPIARYQGLQFVYLSFIYPNDHTRLTHMETENKCFYRESPLYLERFGFYKYMKMDKEEGEEDEEEEVQRRAFLFLNPDDFLDDED------------EQELLDSLEPTDASLQQS-HRTPTPAASPETTASPTPP---------------------------TTS-PLDEQTLR-----HSRALNWAP---------------------------------RPLPLFLGRAPPPR------------------TSEKSSSKVYVTRVRPGQRASPRALRD-SPWPPFPGVFLRP--KPLPRVQLRVPP---------------HPPRTQGYRTSSPKVTELRPPVRAQTN-------QGGQEGQLHGQG---LMVPTVDLNSSVETQS------VTSFLSLSQVSRPQLPGEGE---EGE-DGAPGDEATSEDSEEEEEQAAGRPLGRWREDAIDWQRTFSVGAMDFELLRSDWNDLRCNVSGNLQLPETEAVDVVAQYMERLNARHGGRFSLLRIVNVEKRRDSARGSRFLLELELQERGGSRQRLSEYVFLRLPGARVGD-------EDGDSP----EPPPAASSHPDSR--------------PELCRPLHLAWRQDVMVHFIVPVKNQARWVVQFLADMTALHVQTGDSYFNIILVDFESEDMDVERALRAAQLPRYQYLRRTGNFERSAGLQTGVDAVEDPSSIVFLCDLHIHFPPNILDSIRKHCVEGKLAFAPVVMRLGCGSSPWDPHGYWEVNGFGLFGIYKSDFDRVGGMNTEEFRDQWGGEDWELLDRVLQAGLEVERLRLRHFYHHYHSKRGMWATRSRKGARAHRS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q766D5-1", "uniprot_id": "B4GN4_MOUSE", "id": "Q766D5-1", "name": "N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1", "aln": "MPWFPVKKVRKQMKLLLLLLLLTCAAWLTYVHRSLVRPGRALRQRLGYGRDGEKLTGVTDS---RGVRVPSSTQRSEDSSESHEEE--QAPEGRGPNMLFPGGPRKPPPLNLTHQTPPWR---------EEFKGQVNLHVFEDWCGGAVGHLRRNLHFPLFPHTRTTVTKLAVSPKWKNYGLRIFGFIHPARDGDIQFSVASDDNSEFWLSLDESPAAAQLVAFVGKTGSEWTAPGEFTKFSSQVSKPRRLMASRRYYFELLHKQDDKGSDHVEVGWRAFLPGLKFEIIDSAHISLYTDESSLKMDHVAHVPQSPASHIGGFPP---QGEPSADMLHPDPRDTFFLTPRMEPLSLENVLEPCAYAPTYILKDFPIARYQGLQFVYLSFIYPNDHTRLTHMETDNKCFYRESPLYLERFGFYKYMKMDKEEGEEDEEEEVQRRAFLFLNPDDFLDEED------------EQDLLDSLEPTDASVQQS-HRTPTPAASTGTTASPTPP---------------------------TTS-PLDEQTLR-----HSRALNWAP---------------------------------RPLPLFLGRAPPPR------------------TVEKSPSKVYVTRVRPGQRASPRALRD-SPWPPFPGVFLRP--KPLPRVQLRVPP---------------HPPRTQGYRTSGPKVTELKPPVRAQTS-------QGGREGQLHGQG---LMVPTVDLNSSVETQP------VTSFLSLSQVSRPQLPGEGE---EGEEDGAPGDEATSEDSEEEEEPAAGRPLGRWREDAINWQRTFSVGAMDFELLRSDWNDLRCNVSGNLQLPEAEAVDVVAQYMERLNAKHGGRFSLLRIVNVEKRRDSARGSRFLLELELQERGGSRQRLSEYVFLRLPGARVGD-------EDGESP----EPPPAASIHPDSR--------------PELCRPLHLAWRQDVMVHFIVPVKNQARWVVQFLADMTALHVHTGDSYFNIILVDFESEDMDVERALRAAQLPRYQYLKRTGNFERSAGLQTGVDAVEDPSSIVFLCDLHIHFPPNILDSIRKHCVEGKLAFAPVVMRLGCGSSPWDPHGYWEVNGFGLFGIYKSDFDRVGGMNTEEFRDQWGGEDWELLDRVLQAGLEVERLRLRHFYHHYHSKRGMWATRSRKGARAQRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q76KP1-1", "uniprot_id": "B4GN4_HUMAN", "id": "Q76KP1-1", "name": "N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1", "aln": "MPRLPVKKIRKQMKLLLLLLLLSCAAWLTYVHLGLVRQGRALRQRLGYGRDGEKLTSETDG---RGVHAAPSTQRAEDSSESREEE--QAPEGRDLDMLFPGGAGR-LPLNFTHQTPPWR---------EEYKGQVNLHVFEDWCGGAVGHLRRNLHFPLFPHTRTTVKKLAVSPKWKNYGLRIFGFIHPARDGDVQFSVASDDNSEFWLSLDESPAAAQLVAFVGKTGSEWTAPGEFTKFSSQVSKPRRLMASRRYYFELLHKQDDRGSDHVEVGWRAFLPGLKFEVISSAHISLYTDESALKMDHVAHVPQSPASHVGGRPP---QEETSADMLRPDPRDTFFLTPRMESSSLENVLEPCAYAPTYVVKDFPIARYQGLQFVYLSFVYPNDYTRLTHMETDNKCFYRESPLYLERFGFYKYMKMDKEEGDEDEEDEVQRRAFLFLNPDDFLDDED------------EGELLDSLEPTEAAPPRSGPQSPAPAAPAQPGATLAPP---------------------------TPPRPRDGGTPR-----HSRALSWAARA------------------------------ARPLPLFLGRAPPPRP-----------------AVEQPPPKVYVTRVRPGQRASPRAPAPRAPWPPFPGVFLHP--RPLPRVQLRAPP---------------RPPRPHGRRTGGPQATQPRPPARAQAT-------QGGREGQARTLG---PAAPTVDSNLSSEARP------VTSFLSLSQVSGPQLPGEGEEEEEGEDDGAPGDEAASEDSEE----AAGPALGRWREDAIDWQRTFSVGAVDFELLRSDWNDLRCNVSGNLQLPEAEAVDVTAQYMERLNARHGGRFALLRIVNVEKRRDSARGSRFLLELELQERGGGRLRLSEYVFLRLPGARVGD-------ADGESP----EPAPAASVRPDGR--------------PELCRPLRLAWRQDVMVHFIVPVKNQARWVAQFLADMAALHARTGDSRFSVVLVDFESEDMDVERALRAARLPRYQYLRRTGNFERSAGLQAGVDAVEDASSIVFLCDLHIHFPPNILDGIRKHCVEGRLAFAPVVMRLSCGSSPRDPHGYWEVNGFGLFGIYKSDFDRVGGMNTEEFRDQWGGEDWELLDRVLQAGLEVERLRLRNFYHHYHSKRGMWSVRSRKGSRTGAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TFQ2-1", "uniprot_id": "A0AB32TFQ2_DANRE", "id": "A0AB32TFQ2-1", "name": "Beta-1,4-N-acetylgalactosaminyltransferase", "aln": "MLRFPVKKIRKQFKLLLLLVLLTFAVWFTYLH---INQGKSIKLHFNYGKDGERPMEGTDTSHKRDSRSSDKYRKSEDASNSQEEDNTQEDEPNAGTAHNKDQAEIRKLLAQKYKKLPWKPERDFALAIVKFKGQANLHVFEDWCGSSVAQLRKNLHFPLYPHTRTTVKKLAVAPKWKNYGLRIFGYILPYKDGDFQFAVSSDDNSEFWLSSDESPLNARLLAYVGKLGSEWTAPGEFTKFRSQASKSVHLMASRRYYFEILHKQDDKGSDHVEVGWRPFLPGLKYEVIDSAYISLYTDESSLKMNHVDHIPQTLASHSRVPAETHIHSQHGADMLQPDPRDTFFNIPMIDPAHLENVLPACLYSPTYVVKDFPIARYQGLQFVYLSFVYPNDFTRLTHMEKENKCFYRESPIYLEKFGFYKYMKMDEEEDD---------RPFFFPNPDDFLEEEEGVDPDDEAQVVGTQSAKKTIQPSQSTHTLSPSDKPVPTMLDRKEVEPGNPALRREQRRFFASARQPVVPEAQEMEKDTPDHQINVGSPKSESVVRGRSLAWVQRDRREGWSEERSPKISRTALLFPPKSSLVALNSRAKQILSNPNPSPANNHAHDNNRNPGNIHANKEHKKEDNKIYVTRPRPAR--EKQGLVSRHPREVFPGVFLYQNGKTTKLVNLSAKPKLGKGPLRASQLFARSPLQESKVFPASPNFSNPIPPNRAAIPSHFERRIRGVWEKHQHPLRPVTTLRPTPQSSNSSENVPPTESVRVTSYMHTSQITESQQQRPDT-DLEPEEDGGLS-EYSYEDVEP---------RPGWAEEAINWQRTFSVNSMDFESLRSDWNDLRCNVSGNLQLSESEVVDVLAQYMEKLNERNGGIYTLLRIINVEKRRDSARGNRYLVELELMERGRKIVRLSEYIYMLLHRGRAEDSLENVEGVTASSPSSPVASPPAQPSHTPTRGARGTPQWGTVYAKPLLCQPVMLRWKKDVMVHFVVPVKNQARWVQQFISDMESLHSETKDNNFNIIIVDFQSEDMDVEQALRESTVPRYEYLRREGNFERSAGLQIGVDTIEDSHSIVFLCDLHIHFPPNILENIRKHCVEGKLAFAPIVMRLGCGSSPLEPDGYWEVNGFGLFGIYKSDFDKIGGMNTEEFKDRWGGEDWELLDRVLQNGLEVERLRLRNFFHYYHSKRGMWNSQSSKTPK----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :****:***:******:**: *.*:**:* :. *:::: ::.**:***: ** *. : . . :::**:*:*:**: * * . . . * .::. **: ::***.**********.:*.:**:******:*******.****:************:* * :***.**:*:********** **** *:*:*:*** ************* **.**. :**********:******:**********.******:*:*.**:********:***:** *:**: *** . : : .****:******** * ::. ***** .* *:***::******************:****.*******.:*********:***:**********:**.: *.*:* ******::*: . .:::*:::: * .*.*: . * *. : : : :.*:* *. *. :: . *.* :: *:**** **.: . :. * ****** :. *:* . * * : ...*: :: ** ** :* * : : ** : . * * . ***:: **:: .* . * * **. . * : ** * * *:**:*******.::*** ******************.*:*.*** *****:** ::** ::****:***********.*:*:**** *** *****::: * .*. * ..** ..** . :. * * **:*: * *::******:********** **::** :** .* *. *.:::***:*******:*** : :***:**:* ********** ***::**. *****************:.********:*****:****.***** :*.*******************::********:*:************** **********:*:*:******** :* * .: ", "identical_positions": 579, "similar_positions": 226, "identity": "47.85%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100422-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q76KP1-1", "uniprot_id": "B4GN4_HUMAN", "id": "Q76KP1-1", "name": "N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1", "aln": "-MPRLPVKKIRKQMKLLLLLLLLSCAAWLTYVHLGLVRQGRALRQRLGYGRDGE-KLTSETDGRGVHAAPSTQRAEDSSESREEEQAPEGRDLDMLFP---GGAGR-LPLNFTHQTPPWREEYKGQVNLHVFEDWCGGAVGHLRRNLHFPLFPHTRTTVKKLAVSPKWKNYGLRIFGFIHPARDGDVQFSVASDDNSEFWLSLDESPAAAQLVAFVGKTGSEWTAPGEFTKFSSQVSKPRRLMASRRYYFELLHKQDDRGSDHVEVGWRAFLPGLKFEVISSAHISLYTDESALKMDHVAHVPQSPASH---VGGRPPQEETSADMLRPDPRDTFFLTPRMESSSLENVLEPCAYAPTYVVKDFPIARYQGLQFVYLSFVYPNDYTRLTHMETDNKCFYRESPLYLERFGFYKYMKMDKEEGDEDEEDEVQRRAFLFLNPDDFLDDEDEGELLDSLEPTEAAPPRSGPQSPAPAAPAQPGATLAP------------------------PTPPRPRDGGTPRHS----------RALSWAARAARPLPLFLGRAPPPRPAVEQPPPKVYVTRVR--------PGQRASPRAPAPRAPWPPFPGVFLHPRP--LPRVQLRAPPRPPRPHGRRTGGPQATQPRPPAR--------------AQATQGGREGQARTLGPAAPTVDSNLS---------SEARPVTSFLSLSQVSGPQLPG--------------EGEEEEEGEDDGAPGDEAASEDSEE--------AAGPALG-----------------------RWREDAIDWQRTFSVGAVDFELLRSDWNDLRCNVSGNLQLPEAEAVDVTAQYMERLNARHGGRFALLRIVNVEKRRDSARGSRFLLELELQERGGGRLRLSEYVFLRLPGARVGD----ADGESPE--------PAPAASVRPD----------GRPELCRPLRLAWRQDVMVHFIVPVKNQARWVAQFLADMAALHARTGDSRFSVVLVDFESEDMDVERALRAARLPRYQYLRRTGNFERSAGLQAGVDAVEDASSIVFLCDLHIHFPPNILDGIRKHCVEGRLAFAPVVMRLSCGSSPRDPHGYWEVNGFGLFGIYKSDFDRVGGMNTEEFRDQWGGEDWELLDRVLQAGLEVERLRLRNFYHHYHSKRGMWSVRSRKGSRTGAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q766D5-1", "uniprot_id": "B4GN4_MOUSE", "id": "Q766D5-1", "name": "N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1", "aln": "-MPWFPVKKVRKQMKLLLLLLLLTCAAWLTYVHRSLVRPGRALRQRLGYGRDGE-KLTGVTDSRGVRVPSSTQRSEDSSESHEEEQAPEGRGPNMLFP---GGPRKPPPLNLTHQTPPWREEFKGQVNLHVFEDWCGGAVGHLRRNLHFPLFPHTRTTVTKLAVSPKWKNYGLRIFGFIHPARDGDIQFSVASDDNSEFWLSLDESPAAAQLVAFVGKTGSEWTAPGEFTKFSSQVSKPRRLMASRRYYFELLHKQDDKGSDHVEVGWRAFLPGLKFEIIDSAHISLYTDESSLKMDHVAHVPQSPASH---IGGFPPQGEPSADMLHPDPRDTFFLTPRMEPLSLENVLEPCAYAPTYILKDFPIARYQGLQFVYLSFIYPNDHTRLTHMETDNKCFYRESPLYLERFGFYKYMKMDKEEGEEDEEEEVQRRAFLFLNPDDFLDEEDEQDLLDSLEPTDASVQQS-HRTPTPAASTGTTASPTP------------------------PTTS-PLDEQTLRHS----------RALNWAP---RPLPLFLGRAPPPR-TVEKSPSKVYVTRVR--------PGQRASPRALRD-SPWPPFPGVFLRPKP--LPRVQLRVPPHPPRTQGYRTSGPKVTELKPPVR--------------AQTSQGGREGQLHGQGLMVPTVDLNSS---------VETQPVTSFLSLSQVSRPQLPG--------------EGEE---GEEDGAPGDEATSEDSEEE----EEPAAGRPLG-----------------------RWREDAINWQRTFSVGAMDFELLRSDWNDLRCNVSGNLQLPEAEAVDVVAQYMERLNAKHGGRFSLLRIVNVEKRRDSARGSRFLLELELQERGGSRQRLSEYVFLRLPGARVGD----EDGESPE--------PPPAASIHPD----------SRPELCRPLHLAWRQDVMVHFIVPVKNQARWVVQFLADMTALHVHTGDSYFNIILVDFESEDMDVERALRAAQLPRYQYLKRTGNFERSAGLQTGVDAVEDPSSIVFLCDLHIHFPPNILDSIRKHCVEGKLAFAPVVMRLGCGSSPWDPHGYWEVNGFGLFGIYKSDFDRVGGMNTEEFRDQWGGEDWELLDRVLQAGLEVERLRLRHFYHHYHSKRGMWATRSRKGARAQRS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FE27-1", "uniprot_id": "E7FE27_DANRE", "id": "E7FE27-1", "name": "Beta-1,4-N-acetylgalactosaminyltransferase", "aln": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLH---INQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQ---------PVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:**:***:******:** * :**:* :. *:*:: ::.**:* * : . .. : ..* : *... : .:*:. *. : ... * .. **: *:***.**********.:*.:**:******:*******.*:**:*********:****** :***.**::*******:*** **** *:*:.:**: **********:** **.*** ***:*******:******:**********.**** **::*.**:********:***: * *:**: *** : :****:*******: * :: ***** .*.*:***::*****************::****.*******. *********:***:**********:**.:: ..:* :*****::*: : ::::.:: . :* :. .: . :: . : . . *** * :. :. .. . *.. . * .. . * * * *. ::..: :* . * *: *.. * . :* : .:. *. :**. *: :. * : * : :: . :::*. *::* * ** :. .*. . ** :::*: .** * * :. : *:**:*******..:**********************.* *.:** :*:***** :: * ::* **************.*:*:** * * * *****::* * :*. : :* *. * *:.* .:* **:*: * **:******:********** **::** ** .* *. *.:::***:*:*****:**: : :***:**:* ******:*** ***::**. ************* ***:.********:*****:****.***** :*.*:*****************::********:*:************** **********:***::******* . ::.:: ", "identical_positions": 531, "similar_positions": 258, "identity": "44.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100422-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q05140-1", "uniprot_id": "AP180_RAT", "id": "Q05140-1", "name": "Clathrin coat assembly protein AP180", "aln": "--MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMADTLFERATNSSWVVVFKALVTTHHLMVHG-NERFIQYLASRNTLFNLSNFLDK-----------SGSHGYDMSTFIRRYSRYLNEKAFSYRQMAFDFARVKKG-ADGVMR--------TMVPEKLLKSMPILQGQIDALLEFDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRFLTRMTRVSEFLKVADEVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDIFATASAAAPVSSAKPSSDLLDLQPDFS--GARAGAAAPVPPPTGGATAWGDLLGEDSLAALSSVPSEAPISDPFAPEPSPPTTTTEP--ASASAS--ATTAVTAATTEVDLFGDAFAASPGEAPAASEGATAPATPAPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSAPVVTPTASTAPPVPATAPSPAPTAVAATAATTTAAAAATTTATTSAAAATTAAAPPALDIFGDLFDSAPEVAAASKPDVA-PSIDLFGTDAFSSPPRGASPVPESSLTADLLSGSGFHCAEDDRHVPLFFTAVDAFAAP----------SPASTASPAKAESSGVIDLFGDAFGSSASETQPAPQAVSSSSASADLLAGFGGSFMAPSTTPVTPAQNNLLQP-NFEAAFG-------------TTPSTSSSSSFDPS-----GDLLMP-----------------------------TMAPSGQPAPVSMVPPSPAMSASKGLGSDLDSSLASLVGNLGISGTTSKKGDLQWNAGEKKLTGGANWQPKVTPATWSAGVPP----QGTVP--PTSSVPPGAGAPSVGQPGAGYGMPPAGTGMTMMPQQPVMFAQPMMRPPFGAAAVPGTQLSP-SPTPATQSPKKPPAKDPLADLNIKDFL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61548-1", "uniprot_id": "AP180_MOUSE", "id": "Q61548-1", "name": "Clathrin coat assembly protein AP180", "aln": "--MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMADTLFERATNSSWVVVFKALVTTHHLMVHG-NERFIQYLASRNTLFNLSNFLDK-----------SGSHGYDMSTFIRRYSRYLNEKAFSYRQMAFDFARVKKG-ADGVMR--------TMVPEKLLKSMPILQGQIDALLEFDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRFLTRMTRVSEFLKVAEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDIFATASAAAPVSSAKPSSDLLDLQPDFS--GAAAGAAAPVVPPSGGATAWGDLLGEDSLAALSSVPCEAPISDPFAPEPSPPTTTTEP--ASASAS--TTTAVTAVTTEVDLFGDAFAASPGEAPAASEGATAPATPAPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSAPVVTPTASTAPPVPATAPSPAPTAVAATAATTTAAAAATTTATTSAAAATTAAAPPALDIFGDLFDSAPEVAAAPKPDAA-PSIDLFGTDAFSSPPRGASPVPESSLTADLLS-------------------VDAFAAP----------SPASTASPAKAESSGVIDLFGDAFGSGASETQPAPQAVSSSSASADLLAGFGGSFMAPSTTPVTPAQNNLLQP-SFEAAFG-------------TTPSTSSSSSFDPSVFDGLGDLLMP-----------------------------TMAPSGQPAPVSMVPPSPAMAASKGLGSDLDSSLASLVGNLGISGTTSKKGDLQWNAGEKKLTGGANWQPKVTPATWSAGVPP----QGTVP--PTSSVPPGAGAPSVGQPGAGFGMPPSGTGMTMMSQQPVMFAQPMMRPPFGAAAVPGTQLSP-SPTPATQSPKKPPAKDPLADLNIKDFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60641-1", "uniprot_id": "AP180_HUMAN", "id": "O60641-1", "name": "Clathrin coat assembly protein AP180", "aln": "--MSGQTLTDRIAAAQYSVTGSAVARAVCKATTHEVMGPKKKHLDYLIQATNETNVNIPQMADTLFERATNSSWVVVFKALVTTHHLMVHG-NERFIQYLASRNTLFNLSNFLDK-----------SGSHGYDMSTFIRRYSRYLNEKAFSYRQMAFDFARVKKG-ADGVMR--------TMAPEKLLKSMPILQGQIDALLEFDVHPNELTNGVINAAFMLLFKDLIKLFACYNDGVINLLEKFFEMKKGQCKDALEIYKRFLTRMTRVSEFLKVAEQVGIDKGDIPDLTQAPSSLMETLEQHLNTLEGKKPGNNEGSGAPSPLSKSSPATTVTSPNSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAGGATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASASAS--TTTTVTAVTAEVDLFGDAFAASPGEAPAASEGAAAPATPTPVAAALDACSGNDPFAPSEGSAEAAPELDLFAMKPPETSVPVVTPTASTAPPVPATAPSPAPAVAAAAAATTAATAAATTTTTTSAATATT--APPALDIFGDLFESTPEVAAAPKPDAA-PSIDLFSTDAFSSPPQGASPVPESSLTADLLS-------------------VDAFAAP----------SPATTASPAKVDSSGVIDLFGDAFGSSASEPQPASQAASSSSASADLLAGFGGSFMAPSPSPVTPAQNNLLQP-NFEAAFG-------------TTPSTSSSSSFDPSVFDGLGDLLMP-----------------------------TMAPAGQPAPVSMVPPSPAMAASKALGSDLDSSLASLVGNLGISGTTTKKGDLQWNAGEKKLTGGANWQPKVAPATWSAGVPPSAPLQGAVP--PTSSVPPVAGAPSVGQPGAGFGMPPAGTGMPMMPQQPVMFAQPMMRPPFGAAAVPGTQLSP-SPTPASQSPKKPPAKDPLADLNIKDFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T6A8-1", "uniprot_id": "A0A8N7T6A8_DANRE", "id": "A0A8N7T6A8-1", "name": "Clathrin coat assembly protein AP180", "aln": "--MSGQTLTDRIAAAQYSLTGSEVARAVCKATTHEVMAPKKKHLEYLIQATQESNVNIPQMADTLFERAGNASWIVVFKALVATHHLMVHG-NERFIQYLASRNTLFNLSNFLDK-----------TGSHGYDMSTFIRRYSRYLNEKAFAYRQMAFDFGRVKKG-ADGVMR--------TMTPDKLLKGMPTLQSQIDALLEFDVHPKDLVNGVINAAFLLLFKDLIKLYACYNDGIINLLEKFFQMKKGQCKDALEIYKRFLTRMTRVSEFLKIAEQVGIDKNDIPELTQAPESLLESLETHLNTLEGKK---------VSPTKKGSPTNNGT-PAGTPAKSAEPSAAVTEPAASEPTKAAPAKTTINSGFNDLVDFDLLAPTAGVSAAP------TASWGDLLGGDSLAAPASASSEAPLSEAESASAAAATEPAADAISAPAAASLPVPTSTATTSDMDLFGDAFAPSPGDGP--SEGFAP-------AAAADACAGSDPWATSEGSASIAPELDLFAMKPVESVS--VAAAASPTSAEPVISPTEAPETLSPATNTTTTTS---TTTTVTASATAEPAAPPTLDLFSDMFDSMPEQSSSTEPKASTPSVDLFGADLPAVS-RGPSPLPETNVTGDLLS--------------------DSFVAPAVAPVVPAPAAPAAPVSPPKAEPGPVLDLL-DTFGDTTAESQSAAPGAPSGDLLGGLISPVAPTVTPTPAVVPSSAPADLLES-GFD-AFGSLPVSSTPVVVDSTNSTTAPSGGFDASVFDGLGDLLMPAITPQSTGGTPMAAASPQLAPGLMPTAGPTMVPAMAPAMAPTMVPAAAAQPVKPIGGDLDSSLANLVGNLGV---VSQKKDNQWN--EKKLTGGANWTPQVALSSWGTPGAQ---MPGSAPGAPGAAAPPGAMAPPMG-AQPSFGMPPAAAGAPIMP-QPVMMGQPMMRPQFTGPSATGTPGAPLSPGPAAQSPKKPPSKDPLADLNIKDFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VI75-1", "uniprot_id": "PICAL_DROME", "id": "Q9VI75-1", "name": "Phosphatidylinositol-binding clathrin assembly protein LAP", "aln": "MTMAGQTINDRLLAARHSLAGQGLAKSVCKATTEECIGPKKKHLDYLVHCTNEPNVSIPHLANLLIERSQNANWVVVYKSLITTHHLMAYG-NERFMQYLASSNSTFNLSSFLDKGTVQDGGMGVPGGRMGYDMSPFIRRYAKYLNEKSLSYRAMAFDFCKVKRGKEEGSLR--------SMNAEKLLKTLPVLQAQLDALLEFDCQSNDLSNGVINMSFMLLFRDLIRLFACYNDGIINLLEKYFDMNKKHARDALDLYKKFLVRMDRVGEFLKVAENVGIDKGDIPDLTKAPSSLLDALEQHLATLEGRK--------------------------------------------------VSAAN----------------------------------------------------------------------------------------TPTQSSSSAFGTAAASS----------------------KFDTTNGIDEQLKAQVLAEEEAAMNQYKSK--------------------VSSPTSSGAAGASAALTN------------------------------------PFLSSPPAAQAGQPIVDLFG----------------------------------------------------------------------------------------AASAQPAAAAAAT------------------------KASDDLLQLG------------------------NPFADMFDAS--------------------------------------------------------GGGAAAVGATGNAGDG--------------------------TAKYDGGAGSSP----FDWGATDDD----GGAAQ-------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53309-1", "uniprot_id": "AP18B_YEAST", "id": "P53309-1", "name": "Clathrin coat assembly protein AP180B", "aln": "-------------------MSSLYTKLVKGATKIKMAPPKQKYVDPILSGTS-SARGLQEITHALDIRLSDTAWTIVYKALIVLHLMIQQGEKDVTLRHYSHNLDVFQLRKISHT-----------TKWSSNDMRALQR-YDEYLKTRCEEYGRLGMDHLRDNYSSLKLGS-------KNQLSMDEELDHVESLEIQINALIRNKYSVSDLENHLLLYAFQLLVQDLLGLYNALNEGVITLLESFFELSIEHAKRTLDLYKDFVDMTEYVVRYLKIGKAVGLK---IPVIKHITTKLINSLEEHLREETKRQ----------------------RGEPSEPQQDRKPSTAISSTSSHNNNSNDKNKSIAQKKLEQIRE-----------------------------------------------------------------------------QKRLLEQQLQNQQLLISPTVP-----------------QDAYNPFGSQQQDLNNDTFSFEPTQPQMTAQVPQPTANPFLIPQQQQQALQLTSASTMPQ------PSEIQIT-------------------PNLN--------NQQTGMYASNLQYTPNFTGSGFGGYTTTENNAIMTG-TLDPTKTGS-------------------------------------------------------------NNPFSLENIAREQQ--------------QQNFQNSPNPFTLQQAQTT---------------------PILAHSQTGNPFQAQ-----------------------------------------------------------NVVTSPMGTYMTN--------------------------PVAGQ----------------------LQYASTG-------AQQQPQMMQGQ-QTGYVMVPTA------------------FVPINQQQQQ-----------QQHQQE---------NPNLIDI-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38856-1", "uniprot_id": "AP18A_YEAST", "id": "P38856-1", "name": "Clathrin coat assembly protein AP180A", "aln": "--------------------MTTYFKLVKGATKIKSAPPKQKYLDPILLGTS-NEEDFYEIVKGLDSRINDTAWTIVYKSLLVVHLMIREGSKDVALRYYSRNLEFFDIENIRGS-----------NGSASGDMRALDR-YDNYLKVRCREFGKIKKDYVRDGYRTLKLNSGNYGSSRNKQHSINIALDHVESLEVQIQALIKNKYTQYDLSNELIIFGFKLLIQDLLALYNALNEGIITLLESFFELSHHNAERTLDLYKTFVDLTEHVVRYLKSGKTAGLK---IPVIKHITTKLVRSLEEHLIED-----------------------------------DKTHNTFVPVDSSQGSAGAVVAKSTAQERLEQIRE-----------------------------------------------------------------------------QKRILEAQLKNEQVAISPALTTV-------------TAAQSYNPFGTDS--------SMHTNIPMAVANQTQQIANNPFVSQTQPQVMNTPTAHTEPANLNVPEYAAVQHT-------------------VNFNPVQDAGVSAQQTGYYSINNHLTPTFTGAGFGGYSVSQDTTAASNQQVSHSQTGS-------------------------------------------------------------NNPFALHNAATIATGNPAHENVLNNPFSRPNFDEQNTNMPLQQQIISN--------------------PFQNQTYNQQQFQQQ-----------------------------------------------------------KMPLSSINSVMTT--------------------------PTSMQGSMNIPQRFDKMEFQAHYTQNHLQQQQQQ-------QQQQQQQQQQQPQQGYYVPATAGANPVTNITGTVQPQNFPFYPQQQPQPE-----------QSQTQQPVLGNQYANNLNLIDM-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * **. : **:*::: :: *. .: .:.. * * :: * :*:*:*:. * :: * :: ::: : *:: .: . . ** .: * * .**: :. : : *. : . : *. : *: *::**:. . :* * :: .* **.:**: *: . *:*:*.***.:*::. :.. :*::** *: * .:** .. .*:. ** :.: . .*: :** ** . . . . * * : . . : :. : . . * . . . . . . *: . . ", "identical_positions": 62, "similar_positions": 117, "identity": "6.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100422-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5TGI0-1", "uniprot_id": "FAXC_HUMAN", "id": "Q5TGI0-1", "name": "Failed axon connections homolog", "aln": "MHWGVGFASSRPCVVDLSWNQSISFFGWWAGSEEPFSFYGDIIAFPLQDYGGIMAGLGSDPWWKKTLYLTGGALLAAAAYLLHELLVIRKQQEIDSKDAIILHQFARPNNGVPSLSPFCLKMETYLRMADLPYQNYFGGKLSAQGKMPWIEYNHEKVSGTEFIIDFLEEKLGVNLNKNLGPHERAISRAVTKMVEEHFYWTLAYCQWVDNLNETRKMLSLSGGGPFSNLLRWVVCHITKGIVKREMHGHGIGRFSEEEIYMLMEKDMRSLAGLLGDKKYIMGPKLSTLDATVFGHLAQAMWTLPGTRPERLIKGELINLAMYCERIRRKFWPEWHHDDDNTIYESEESSEGSKTHTPLLDFSFYSRTETFEDEGAENSFSRTPDTDFTGHSLFDSDVDMD-DYTDHEQCK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UMF9-1", "uniprot_id": "FAXC_MOUSE", "id": "Q3UMF9-1", "name": "Failed axon connections homolog", "aln": "MHWGVGFASSRPCVVDLSWNQSISFFGWWAGSEEPFSFYGDIIAFPLQDYGGIMAGLGSDPWWKKTLYLTGGALLAAAAYLLHELLVIRKQQELDSKDAIILHQFARPNNGVPSLSPFCLKMETYLRMADLPYQNYFGGKLSAQGKMPWIEYNNEKVSGTEFIIDFLEEKLGVNLNKSLGPHERAVSRAVTKMVEEHFYWTLAYCQWVDNLNETRKMLSLSGGGPFSNLLRWVVCHITKGIVKREMHGHGIGRFSEEEIYMLMEKDMRSLAGLLGDKKYIMGPKLSTLDATVFGHLAQAMWTLPGTRPERLIKGELINLAMYCERIRRKFWPEWHHDDDNTIYESEESSEGSKTHTPMLDFSFYSRTETFEDEGAENSFSRTPDTDFTGHSLFDSDVEMD-DYTDHEQCK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FFZ1-1", "uniprot_id": "E7FFZ1_DANRE", "id": "E7FFZ1-1", "name": "", "aln": "MYWRVGFGWSRSCALELGRNRSFSFG--LCRSDEQMSLHGFIIAYPLQEYGGIMSALGVDSWWRKTLYITGGALLAAAAYLLHELLVIRKEQELDSEDTIILHQFARPKTGVPSLSPFCLKIETYLRMADLPYQNYFDGQLSPQGKMPWIAYNKEQVCGTEFIIDFLEEQLGVNLNSSLSPQEKAISRAITKMVEEHFYWTIAYCQWVDNVEETQKMLSTNG--PLSDLLRQILGQVTGGIVKREMYGHGIGRFSRDEVYKLMEKDMRTLATLLGNKKYLMGQTFSTVDAAVFGHLAQAMWTLPGTRPEQLIKGEFINLAMYCERIRRKFWPEWFVDVDDLYYDG--LSEEPDSPSQLQDLGLHSCSFQEQESSVSHQDTPSPDSDITGRSLCDSDMDTECSVSEAELLK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* ***. **.*.::*. *:*:** . *:* :*::* ***:***:*****:.** *.**:****:*********************:**:**:*:*********:.***********:***************.*:**.******* **:*:*.***********:******..*.*:*:*:***:***********:********::**:**** .* *:*:*** :: ::* *******:********.:*:* *******:** ***:***:** .:**:**:******************:*****:******************. * *: *:. ** ..: : : *:.::* : ::....:. : :**:*:**:** ***:: : . :: * *", "identical_positions": 266, "similar_positions": 99, "identity": "64.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100422-9", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACL6-1", "uniprot_id": "D4ACL6_RAT", "id": "D4ACL6-1", "name": "Ras association domain-containing protein 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MSSGYSSLEEDAEDFFFTARTS-----------FFRRAPPGKSRSGQPDVEKEKETHNYLSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPAQTPAN-----------PSSSGCMNTLHISSTNTVGDVIDALLKKFQVTESPTKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGE--WEAFSLPELQNFLRILDKEEDEQLQSLKRRYTAYRQKLEEALG-EVWKPG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99P51-1", "uniprot_id": "RASF3_MOUSE", "id": "Q99P51-1", "name": "Ras association domain-containing protein 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MSSGYSSLEED-EDFFFTARTS-----------FFRRAPPGKSRSGQPDVEKEKETHNYLSKEEIKEKVHKYNSAVTDKLKMTLNSNGIYTGFIKVQMELCKPAQPSPE-----------PSSGGCMNTLHISSTNTVGEVIEALLRKFLVTESPTKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGE--WEAFSLPELQNFLRILDKEEDEQLQSLKRRYTAYRQKLEEALG-EVWKPG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86WH2-1", "uniprot_id": "RASF3_HUMAN", "id": "Q86WH2-1", "name": "Ras association domain-containing protein 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------MSSGYSSLEEDAEDFFFTARTS-----------FFRRAPQGKPRSGQQDVEKEKETHSYLSKEEIKEKVHKYNLAVTDKLKMTLNSNGIYTGFIKVQMELCKPPQTSPNSG------KLSPSSNGCMNTLHISSTNTVGEVIEALLKKFLVTESPAKFALYKRCHREDQVYACKLSDREHPLYLRLVAGPRTDTLSFVLREHEIGE--WEAFSLPELQNFLRILDKEEDEQLQNLKRRYTAYRQKLEEALR-EVWKPD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BBN0-1", "uniprot_id": "A0A8M2BBN0_DANRE", "id": "A0A8M2BBN0-1", "name": "", "aln": "MMHHSRKYSPPRHCAVGSPLPQLNRLPTSRLEEGEPAEKNSPRAKSRMRHAKVKARKAASPQRPRVSPKPAPVVENGGAGQRSRKKGFKPPDVRTIFEPSAKDPRVKEERGEGHAFSEDAAHAWCDVCCSYILQGGLTCTGCKYTCHAQCREQVALDCHQSGSAHLNGVQLSFLAQDQLNNNQASHSDVEKEKELRTHLTFEEIRQKVDRYNRDSRDFYKMSLSSSGTYTGFINVQMDLRRPITVKGGGAGGVKAKEAFYLPRGSINTLHISNSNTVRQVIEALLKKFTVADNPAKFALYKRFSREDQVYTCKLSEEEHPLFLRLVAGPNTDTLSFVLKEQQTGEVMWDAFSIPELQNFIRILEKEEQDQMCSISRRYNTYREKLEEAMKTAAGRPG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. *:. : *:. : .: * *: : .: ::.: ******* :.:*: ***::**.:** * **:*.*.* *****:***:* :* . *.:******.:*** :**:***:** *::.*:******* ******:****:.****:*******.********:*:: ** *:***:******:***:***::*: .:.***.:**:*****: . :*.", "identical_positions": 121, "similar_positions": 69, "identity": "30.48%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100426-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z9P6-1", "uniprot_id": "D3Z9P6_RAT", "id": "D3Z9P6-1", "name": "Epigen", "aln": "MEERLRARSKNPPPFCLGGPEKELRQLQDMALRVPIAVCLLFKAMKAALSEETEAVPPSTTTQQSDWTLNITEADYIEEPVALKFSHPCLEDHNSYCINGACAFHHELKKAICRCFTGYTGERCEHLTLTSYAVDSYEKYIAIGIGVGLLISAFLAVFYCYVRKRCLNVKSPYIICSG-GRPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q924X1-1", "uniprot_id": "EPGN_MOUSE", "id": "Q924X1-1", "name": "Epigen", "aln": "-----------------------------MALGVLIAVCLLFKAMKAALSEEAEVIPPS-TAQQSNWTFNNTEADYIEEPVALKFSHPCLEDHNSYCINGACAFHHELKQAICRCFTGYTGQRCEHLTLTSYAVDSYEKYIAIGIGVGLLISAFLAVFYCYIRKRCINLKSPYIICSG-GSPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UW88-1", "uniprot_id": "EPGN_HUMAN", "id": "Q6UW88-1", "name": "Epigen", "aln": "-----------------------------MALGVPISVYLLFNAMTALTEEAAVTVTPPITAQQGNWTVNKTEADNIEGPIALKFSHLCLEDHNSYCINGACAFHHELEKAICRCFTGYTGERCEHLTLTSYAVDSYEKYIAIGIGVGLLLSGFLVIFYCYIRKRCLKLKSPYNVCSGERRPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IWG0-1", "uniprot_id": "A0A0R4IWG0_DANRE", "id": "A0A0R4IWG0-1", "name": "", "aln": "-----------------------------MTQVLGLMLVLFLFSGLGEAQEKSEDVLLNNTTEN---LLYSHEIE--EEPLVLAAQRPCGSEHEGFCVNGVCSFSTELDTPICRCNEKYSGVRCEHIIMDTRSLSSPEEVIGISCGVVLFLGMLTVLLFFCLKKRCQKSPPPYKNCGSEHSV-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : : : *:: : . .* : : *::: . * : * *:.* .: * .:*:.:*:**.*:* **. .**** *:* ****: : : ::.* *: *.*. ** *::. : .::: ::*** : .** *.. ", "identical_positions": 40, "similar_positions": 54, "identity": "21.86%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100426-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P34926-1", "uniprot_id": "MAP1A_RAT", "id": "P34926-1", "name": "Microtubule-associated protein 1A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGVAEFSEYVSETVDVPSPFDLLEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNILVDGGSDRKSCFWKLVRHLDRIDSVLLTHIGADNLPGINGLLQRKVAELEEEQSQGSSSYSDWVKNLISPELGVVFFNVPDKLRLPDASRKAKRS------IEEACLTLQHLNRLGIQAEPLYRVVSNTIEPLTLFHKMGVGRLDMYVLNPVKDSKEMQFLMQKWAGNSKAKTGIVLANGKEAEISVPYLTSITALVVWLPANPTEKIVRVLFPGNAPQNKILEGLEKLRHLDFLRYPVATQKDLAAGAVPANLKPSKIKHRADSK-------------------------------------------------------------------------ESLKAAPKTAVSKLAKREEVLEEGAKEARSELAK------------------------------------------------------------------------------ELAKTEKKAKEPSEKPPEKPSKSERVR-----------------------------------------------------------------------------------------------------GESSEALKAEKRRLIK-------------------------------------------------------------------------------------------------------DKAGKKHLKEKISKLEEKKDKEKKEIKKERKELKKEEGRKEEKKDAKKDEKRKDTKPEVKKLSK----------PDLKPFTPEVRKTLYKAKAPGRVKVDKGRAARGEKELSS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPRTPPAQKGAAPPAAVSGHRELALSSPEDLTQDFEELKREERGLLAEQRDTGLG-----------------------------------EKPLPADATEQGHPSAAIQVTQPSGPVLEGE-HVEREKEVVPDSPGDKGS-------------------------------------------------------------TNRGPDSGAEVEKEKETWEERKQREAELGPEN-TAAREE---------------------------------SEAEVKEDVIEKAELEEMEETHPSDEEGE---------------------------------------------------------------------ETKAESFYQKHTQEALKASPKSREA------LGGRDLGFQGKAPEKETASFLSSLATPAGATEHVSYIQDETIPGYSETEQTISDEEIHDEPDERPAPPRFPTS---------------------TYDLSGPEGPG-----------------------------------------------------------------------PFEASQAADSAVPASSSKTYG--------------------------------------------APETELTYPPNMVAAPLAEEEHVSSATSITECDKLSSFATSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPS-----SRTEATQGLDYVPSAGTISPTSSLE---------EDKGFKSPPCEDFSVTGESEKKGETVGRGLSGEKAVGKEEK---YVVTSEKLSGQY-AAVFGAPGHTLPPGEPALGEVEERCLSPDDSTVKMASPPPSGPPSAAHTPFHQSPVE--------------------------------------------------------------------DKSEPRDFQE-DSWGETKHSPGVSKEDSEEQTVKPGPEEGTSE-EGKGPPTRSPQAQDMPVSIAGGQTGCTIQLLPEQDKAIVFETGEAGSNLG-----------------------------------------AGTLPGEVRTSTEEATEPQKDEVLRFTDQSLSPEDAESLSVLSVVSPDTTKQEATPR------------------------------------------------------SPCSLKEQQPHKDLWPMVSPEDTQSLSFSEESPSKETSLDISSKQLSPESLGTLQFGELNLGKEERGPVMK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AEDDSCHLAPVSIPEPHRATVSPS-------------TDETPAGTLPGGSFSHSALSVDRKHSPGEITGPGGHFMTSDSSLTKSPESLSSPAMEDLAVEWEGKAPG-------------KEKEPELKSETRQQKGQILPEKVAVVEQDLIIHQKDGALDEENKPGRQQDKTPEQKGRDLDEKDTAAELD-----------------------KGPEPKEKDLDREDQGQ--RAGPPAEKDKASEQRDTDLQQT-QATEPRDRAQERRDSEEKDKSLELRDRTPE-------------------------------------------------------------------------------------------------------------EKDRILVQEDRAPEHSIPEPTQTDRAPDRKGTDDK--EQKEEASEEKEQVLEQKDWALGKEGETLDQEARTAEQKDETLKE-DKTQGQKSSFVEDKTTTSKETVLDQKSAEKADSVEQQDGAALEKTRALGLEESPAEGSKAREQEKKYWKEQDVVQGWRETSPTRGEPVGGQKEPVPAWEGKSPEQ---------------EVRYWRDR-DITLQQDAYWRELSCDRKVWFPHELDGQGARPRYCEERESTFLDEGPD---------------EQEITPLQHTPRSPWTSDFKDFQEPLPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEIISPPASPPEMTGQRVPSAPGQESPVPDTEST----------------------------APMRNEPTTPSWLAEIPPWVPKDRPLPPAPLSPAPAPPTPAPEPHTPVPFSWGLAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREGEGGAGAPDSSSFSPKVPEAGESLATRDTEQTEPE----------------------------------QREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGASGDWPPHLSTKEEAAGCNTSAEKETSSPASPQNLQSDTPAFSYASLAGPAVPPRQEPDPGPNVEPSITPPAVPPRAPISLSKDLSPPLNGSTVSCSPDRRTPSPKE------------------------TGRGHWDDGTNDSDLEKGAREQPEKETRSPSPHHPMPMGHSSLWPETEAYSSLSSDSHLGSVRPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALVPGTPT-----------------------------------------------------------------------------RTRHDEYLEVTKAPSLDSSLPQLPSPSSPGGPLLSNLPRPASP-------------------------------------------------------------ALSEGSSSEATTPVISSVAERFPPGLEAAEQSAEGLGSGKESAAHSLWDLTPLSPAPSASLDLAPAPAPAPAPAP--------------------------------------------------------------------------------------------------GLPGDLGDGTLPCRPECTGELTKKPSPFLSPSGDHEANGPGETSLNPPGFVTATAEKEEAEAPHAWERGSWPEG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AERSSRPDTLLSSEQPLRPGKSSGGPPCSLSSEVEAGPQGCATDPRPHCGELSPSFLNPPLPPSTDDSDLSTEEARLAGKGGRRRVGRPGATGGPCPMADETPPTSASDSGSSQSDSDVPPETEECPS-------------------------------------------------------------------------------------------------------------------------------------------------ITAEAALDSDEDGDFLP-----------VDKAGGVSG-----THHPRPGHDPP----------------------------------------PTPLPDPRPSPPRPDVCMADPEGLSSESGRVERLREK----GRPGRRAPGRAKPASPARRLDIRGKRSPTPGKGPVDRTSRTVPRPRSTPSQVTSAEEKDGHSPMSKGLVN------------------------------------------------------------------------------------GLKAGSTALGSKGGSGPPVYVDLAYIPNHCSGKTADQDFFRRVRASYYVVSGNDPANGEPSRAVLDALLEGKAQWGEN-LQVTLIPTHDTEVTREWYQQTHEQQQQLNVLVLASSS----TVVMQDESFPACKIEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYR6-1", "uniprot_id": "MAP1A_MOUSE", "id": "Q9QYR6-1", "name": "Microtubule-associated protein 1A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGVAEFSEYVSETVDVPSPFDLLEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNILVDGGSDRKSCFWKLVRHLDRIDSVLLTHIGADNLPGINGLLQRKVAELEEEQSQGSSSYSDWVKNLISPELGVVFFNVPDKLRLPDASRKAKRS------IEEACLTLQHLNRLGIQAEPLYRVVSNTIEPLTLFHKMGVGRLDMYVLNPVKDSKEMQFLMQKWAGNSKAKTGIVLANGKEAEISVPYLTSITALVVWLPANPTEKIVRVLFPGNAPQNKILEGLEKLRHLDFLRYPVATQKDLAAGAVPANLKPSKIKHRADSK-------------------------------------------------------------------------ESLKAAPKTAMSKLAKREEVLEEGAKEARSELAK------------------------------------------------------------------------------ELAKSEKKAKEPSEKPPEKPSKPERVR-----------------------------------------------------------------------------------------------------TESSEALKAEKRKLIK-------------------------------------------------------------------------------------------------------DKVGKKHLKEKISKLEEKRDKEKKEIKKERKELKKEEGRKEEKKDAKKDEKRKDTKPELKKFSK----------PDLKPFTPEVRKTLYKAKAPGRLKVDKGRAARGEKELSS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPRTPPAQKGAAPPPAASGHRELALSSPEDLTQDFEELKREERGLLAEPRDTELG-----------------------------------EKPLPADASEQGRPSTAIQVTQPPASVLEQE-QVEREKEVVPDFPEDKGS-------------------------------------------------------------KNRAPDSGAEVEREKETWEERKPREAELTPENIAAAREE---------------------------------SEPEVKEDVIEKAELEEMEEVHPSDEEEE---------------------------------------------------------------------ETKAESFYQKHMQEALKVIPKGREA------LGGRELGFQGKAPEKETASFLSSLATPAGAAEHVSYIQDETIPGYSETEQTISDEEIHDEPDERPAPPRFPTS---------------------TYDLSGPEGPG-----------------------------------------------------------------------PFEASQSAESAVPASSSKTYG--------------------------------------------APETELTYPPNMVAAPLAEEEHVSSATSITECDKLSSFATSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPS-----SRTEATQGLDYVPSAGTISPTSSLE---------EDKGFKSPPCEDFSVTGESEKKGESVGRGLTGEKAVGKEEK---NVTTSEKLSSQY-AAVFGAPGHALHPGEPALGEVEERCLSPDDSTVKMASPPPSGPPSAAHTPFHQSPVE--------------------------------------------------------------------EKSEPQDFQE-DSWGDTKHAPGVSKEDAEEQTVKPGPEEAMSE-EGKVPLSRSPQAQDTLGSLAGGQTGCTIQLLPEQDKAVVFETGEAGAASG-----------------------------------------AGSLPGEVR--TQEPAEPQKDELLGFTDQSFSPEDAESLSVLSVVSPDTAKQEATPR------------------------------------------------------SPCTPKEQQLHKDLWPMVSPEDTQSLSFSEESPSKETSLDISSKQLSPESLGTLQFGELSLGKEEKGPLVK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AEDNSCHLAPVSIPEPHTATVSPPTD---EAAGEAGLTDESPAGNLPGSSFSHSALSGDRKHSPGEITGPGGHFMTSDSSLTKSPESLSSPAMEDLAMEWGGKAPGSEDRATE-----QKEKELERKSETLQQKDQILSEKAALVQRDSVMHQKDEALDEENKPGGQQDKTSEQKGRDLDKKDTAVELG-----------------------KGPEPKGKDLYLEDQG-------LAEKDKALEQRGAALQQT-QAPEPRARAQEHRDLEQKDEHLELRDKTPE-------------------------------------------------------------------------------------------------------------EKDKVLVLEDRAPEHIIPQPTQTDRAPEHRSKVDK--EQKDEASEEKEQVLEQKDWAREKEGAALDQDNRAAGQKDGTLKE-DKTQGQKSSFLEDKSTTPKEMTLDQKSPEKAKGVEQQDGAVPEKTRALGLEESPEEEGKAREQEEKYWKEQDVVQGWRETSPTRGE-------PVPAWEGKSPEQ---------------EVRYWRDR-DITLQQDAYWKELSCERKVWFPHELDGQGARPRYSEERESTFLDEGPN---------------EQEITPLQHTPRSPWASDFKDFQEPLPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEIISPPASPPEMTGQRVPSAPGQESPVPDTKST----------------------------PPTRNEPTTPSWLAEIPPWVPKDRPLPPAPLSPAPAPPTPAPDPHAPAPFSWGIAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREGEGGAGAPDSSSFSSKVPEVTESHTTRDAEQTEPE----------------------------------QREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGASGDWPPHLSTKEEAAGRNKSAEKELSSAVSPPNLHSDTPTFSYASLAGPTIPPRQEPEPGPNVEPSFTPPAVPPRAPISLSQDPSPPLNGSTTSCGPDRRTPSPKE------------------------AGRSHWDDGTNDSDLEKGAREQPEKETQSPSPHHPMPVGHPSLWPETEAHSSLSSDSHLGPVRPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALVPGTPT-----------------------------------------------------------------------------RTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASP-------------------------------------------------------------ALSEGSSSEATTPVISSVAERFPPGLEVAEQSSGELGPGNEPAAHSLWDLTPLSPAPLASRDLAPAPAPAPAPS----------------------------------------------------------------------------------------------------LPGNLGDGTLSCRPECSGELTKKPSPFLSHSGDHEANGPGETSLNPPGFATATAEKEEAEALHAWERGSWPEG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AERSSRPDTLLSSEQ--RPGKSSGGPPCSLSSEVEAGPQGCATDPRPHCGELSPSFLNPPLPPSTDDSDLSTEEARLAGKGGRRRAGRPGATGGPCPMADETPPTSASDSGSSQSDSDVPPETEECPS-------------------------------------------------------------------------------------------------------------------------------------------------ITAEAALDSDEDGDFLP-----------VDKAGGVSG-----THHPRPGHDPP----------------------------------------PAPLPDPRPPPPRPDVCMADPEGLSSESGRVERLREKV--QGRPGRKAPGRAKPASPARRLDIRGKRSPTPGKGPVDRTSRALPRPRSTPSQVTS-EEKDGHSPMSKGLVN------------------------------------------------------------------------------------GLKAGSTALGSKGSSGPPVYVDLAYIPNHCSGKTADQDFFRRVRASYYVVSGNDPANGEPSRAVLDALLEGKAQWGEN-LQVTLIPTHDTEVTREWYQQTHEQQQQLNVLVLASSS----TVVMQDESFPACKIEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78559-1", "uniprot_id": "MAP1A_HUMAN", "id": "P78559-1", "name": "Microtubule-associated protein 1A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGVAEFSEYVSETVDVPSPFDLLEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNILVDGGSDRKSCFWKLVRHLDRIDSVLLTHIGADNLPGINGLLQRKVAELEEEQSQGSSSYSDWVKNLISPELGVVFFNVPEKLRLPDASRKAKRS------IEEACLTLQHLNRLGIQAEPLYRVVSNTIEPLTLFHKMGVGRLDMYVLNPVKDSKEMQFLMQKWAGNSKAKTGIVLPNGKEAEISVPYLTSITALVVWLPANPTEKIVRVLFPGNAPQNKILEGLEKLRHLDFLRYPVATQKDLASGAVPTNLKPSKIKQRADSK-------------------------------------------------------------------------ESLKATTKTAVSKLAKREEVVEEGAKEARSELAK------------------------------------------------------------------------------ELAKTEKKAKESSEKPPEKPAKPERVK-----------------------------------------------------------------------------------------------------TESSEALKAEKRKLIK-------------------------------------------------------------------------------------------------------DKVGKKHLKEKISKLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKISK----------PDLKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPQTPPAQKGTVPLPTISGHRELVLSSPEDLTQDFEEMKREERALLAEQRDTGLG-----------------------------------DKPFPLDTAEEGPPSTAIQGTPPSVPGLGQEEHVMKEKELVPEVPEEQGS-------------------------------------------------------------KDRGLDSGAETEEEKDTWEEKKQREAERLPDR-TEAREE---------------------------------SEPEVKEDVIEKAELEEMEEVHPSDEEEED--------------------------------------------------------------------ATKAEGFYQKHMQEPLKVTPRSREA------FGGRELGLQGKAPEKETSLFLSSLTTPAGATEHVSYIQDETIPGYSETEQTISDEEIHDEPEERPAPPRFHTS---------------------TYDLPGPEGAG-----------------------------------------------------------------------PFEASQPADSAVPATSGKVYG--------------------------------------------TPETELTYPTNIVAAPLAEEEHVSSATSITECDKLSSFATSVAEDQSVASLTAPQTEETGKSSLLLDTVTSIPS-----SRTEATQGLDYVPSAGTISPTSSLE---------EDKGFKSPPCEDFSVTGESEKRGEIIGKGLSGERAVEEEEEETANVEMSEKLCSQYGTPVFSAPGHALHPGEPALGEAEERCLSPDDSTVKMASPPPSGPPSATHTPFHQSPVE--------------------------------------------------------------------EKSEPQDFQEADSWGDTKRTPGVGKEDAAEETVKPGPEEGTLEKEEKVPPPRSPQAQEAPVNIDEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGPILG-------------------------------------AEALPGGLRTLPQEPGKPQKDEVLRYPDRSLSPEDAESLSVLSVPSPDTANQEPTPK------------------------------------------------------SPCGLTEQYLHKDRWPEVSPEDTQSLSLSEESPSKETSLDVSSKQLSPESLGTLQFGELNLGKEEMGHLMQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AEDTSHHTAPMSVPEPHAATASPPTDGTTRYSAQTDITDDSLDRKSPASSFSHSTPSGNGKYLPGAITSPDEHILTPDSSFSKSPESLPGPALEDIAIKWEDKVPGLKDRTSE------QKKEPEPKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKNEAVKQQDKALEQKGRDLEQKDTALEQKD----------------------KALEPKDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKD-----KDLEQKDRVLEQKEKIPE-------------------------------------------------------------------------------------------------------------EKDKALDQKVRSVEHKAPEDTVAEMKDRDLEQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYWALGQKDEALEQNIQALEENHQTQEQESLVQEDK--TRKPKMLEEKSPEKVKAMEEKLEALLEKTKALGLEESLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQ---------------DNRYWRGREDVALEQDTYWRELSCERKVWFPHELDGQGARPHYTEERESTFLDEGPDD--------------EQEVPLREHATRSPWASDFKDFQESSPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEIISPPASPPEMVGQRVPSAPGQESPIPDPKLM----------------------------PHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPE----------------------------------QREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDTPTFSYAALAGPTVPPR--PEPGPSMEPSLTPPAVPPRAPI-LSKGPSPPLNGNILSCSPDRRSPSPKE------------------------SGRSHWDDSTSDSELEKGAREQPEKEAQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPGPPT-----------------------------------------------------------------------------RTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASP-------------------------------------------------------------ALSEGSSSEATTPVISSVAERFSPSLEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAPAPS--------------------------------------------------------------------------------------------------------LPGDMGDGILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSPNPPGPAPAKAENEEAAACPAWERGAWPEG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AERSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELSPSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPTSASDSGSSQSDSDVPPETEECPS-------------------------------------------------------------------------------------------------------------------------------------------------ITAEAALDSDEDGDFLP-----------VDKAGGVSG-----THHPRPGHDPP----------------------------------------PLPQPDPRPSPPRPDVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARRLDLRGKRSPTPGKGPADRASRAPPRPRSTTSQVTPAEEKDGHSPMSKGLVN------------------------------------------------------------------------------------GLKAGPMALSSKGSSGAPVYVDLAYIPNHCSGKTADLDFFRRVRASYYVVSGNDPANGEPSRAVLDALLEGKAQWGEN-LQVTLIPTHDTEVTREWYQQTHEQQQQLNVLVLASSS----TVVMQDESFPACKIEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QUZ1-1", "uniprot_id": "A0A8M1QUZ1_DANRE", "id": "A0A8M1QUZ1-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------MLIVIGDISTDHELDSVKEHIKRGILSWDIDLTFCDLNKELKLFQARHSAQFSSEVKGQRLLQYKSDILETVVLVNPSEENIAIEIRTLVCDSAGHKLLVLSGQSTDRSGDIILQSGAFGWKNLSDILSSRRIKDLLNQPYSGQQACLTVFCKGEGGWSSLGYVQEQSILKYRLNPEPVLP-EMEGVSEFTEYVSETVDVPSPFELLEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNILIDGGSDRKSCFWKLVRHLDRIDSVLLTHIGADNLPGINGLLQRKIAEQEEEKIHGLNTYGDWMKNLISPELGVVFFNVPEKLKMPESTLKAKRS------IEEASLTLQYLHKLGIKPEPLYRVVSNTIEPLTLFHKLGVGKLDMYILNPLKDSKEMQFFMQKWAGNSKAKTGIVLANGKEGEISVPYLTSVTALVVWVPASPTEKIVRVLFPGNAPQNKIFEGLEKLRHLDFLRYPVATQKDMSSGAPPPLIKQTKMKLRTDSK-------------------------------------------------------------------------ESLKSSPKMSSTTKASKKEANEDIESKSESVKEN------------------------------------------------------------------------------KAEKKEKKMKETVKAP-----KPLKPK-----------------------------------------------------------------------------------------------------TASPDSLKLEKKKLQR-------------------------------------------------------------------------------------------------------EKSPKKHVKEKASKMEEKKDLEKKDTKKEKTEVKKDDILKKEKKDK--------VKPELKKITK----------PDLKPFTPEVRKTLNKAKVQVKPKTEKTKAAKEQENRPA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AKQASVEKQ---------EIDRSLVSSPEDLTKDFEALR------LEEELSKSIE-----------------------------------SKILPKVQSAVDTVVPHIESPDEGINTTDVETESPLEERVPYGANANKFASK----------------------------------------------------------ITDRFEDEGAATEYDHTTGLKGAKTSDLARMGEDAMKPKR---------------------------------SDSEEDEDVIEKAELEDAEDIVHEEELKY--------------------------------------------------------------------------------------KSDESRKE------KLGKDWETKSEIKS----------TKSLGAADHVSLIQDETIPGYSETEQTLSDEEINEETEERIPHLQYDVG---------------------SYDISVPDEPG-----------------------------------------------------------------------TFDTIHGMKPPTISVASEFSSK--------------------------------------GFAVDQEPVLSAYATNIVAAPLAEEEHISSATSITEYDKLSSFATSVTEDQSIASVTAPPTEDAGKSSLLLDTINSIPSS----IQTDATQGKEYLHSAGTISPTSSLE---------EDKCFKSPPSEEYQPIVPETETTVKATAPTNYEDEEDEEED-------------EDQTPNVDMPLGKIHEGYASAAILQDTEKASDKIHSSMAPIPPPAMYVGTQERDEKASFE--------------------------------------------------------------------HKSKLSSPEKILSFSPNLPCTSEVNITSESEERCLSPDDSTVR--FASPTQSGPTSGSYSPTEERSQKPLTVDKEEKLDKETVDSYLTKDATSD-------------------------------------------------------------KKSVKIIDDEVDPFVKEFSSTKTAKFDLEDEEEEDYY------------------------------------------------------GKETYKVCGKTKYKEERECTFLDEEYSQEAKPLKEEKLFENKKESVEKESLNDKPQNVTSLGHEHKSQMLS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SGEE--------------------------------------------------DESETEDGVYSSIKAPQGKLDSMSASQGKKDVSFSETDDQNVSKDSD----------------------------------------KSVHFNLYSFPEGEKGLRGEIERVVRQDTPYVGKSFTYSDVYDSKSSSV----------------------DSYSPN---------------------------------------------------LPVEHTFDDTDVTPK-------------------------------------------------------------------------------------------------------------KTEQEDSLDSSTVKFSDPKATDEKQTSDSYSKTQS--------------------------------------------------------------TYMTPQFRDSSEATFSEKINKTEERTFEKTSPISAEKDPLSVQFEKPD-------------------------------FTGMMEVSASQ---------------STHYEADR--LISDYSAKSTSCSLGQSTFGPKEVMAGDMKMFADGEDEDEDEEEDED---------------DEDEEYGEHASDSDTEKGAKEKDAEYP-----MKKVISPVPTQFQDEKKDTVTHDNTRSLGSEDYGKSLG-----------SSTFDTQSK----------------------------GAASSYP--------------------------------------------------------VESHIKCFSGFEHSSSEEKDEFVENHDKVVKSYLPLSTKTAEDKCSHYDDKDLEFDKQQTSDA----------------------------------VEKKTGDPVSLGLGYTTMSATAYSSSSSYSHSSSASASLSTSRQFGDELEAQACTGFDYSSFKDEHSPVNDSPFSSSS---------------GQAKDGYLEVSEKLTPATTTAESTSSLARFSPLSPFEEIKPFPPHAGTCVVDK------------------------KESTYTGSNISDQGLQSQCFYKPEWDEDSRLQAELGATGPFSSVPPATQKDTLPRD--LCGASSTLEFEKQYYEETESSEEEDDYMYETEQ-----DKLQYQRSPVTAQADKKDD-----------------------------------------------------------------------------TFSLSETLSKDISSSLGGAISNMHTSYSLSFPEPTKPDTTNGP-------------------------------------------------------------AEVSLTAAEAFGGACKVETNLSKVEMKGQEFDIKKIRSPSKWQMQQPRDIYPGASPPHYRHEDEYD----------------------------------------------------------------------------------------------------------------EEEETEPEHPARPLSLSSTEKPFQSSYYTDDPNKHDDDSDYPSN------------------VGVRPHS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STASPGYSACENKQRRGDTSPSFINPSLCQLSSDEENEEQTSQASDQQQPVGKTRFHKQPQDYSHSHHCEDNELQHFSG----------AMAAGISASGEDTPPTSISEPLHSQSDSDVPPGTEECPS-------------------------------------------------------------------------------------------------------------------------------------------------ITAKGN-DSDDDADYLP-----------VDKSSGAYGGKHYLSRSPDKNHDPL----------------------------------------PSPLMDPAPYPPHPDACMVDPEALSSLTDKPIKKDTKAK-----GLRKLGKTKSSSPARKADARRKRSPSK-----EPFAHTTSLRKKDMEDDLSRSSHNTGKGLVNGLKN------------------------------------------------------------------------------------TAGSNSSKFSTAVPPGPPIYVDLAYIPNHCSAKNVDQEFFKRVRSAYYVVSGNDSSNGEPSRSVLDALLEGKAQWGSN-LQVTLIPTHDTEVTREWYQQTHEKQQELNIMVLASSS----TVVMQDESFPACKIEF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W596-1", "uniprot_id": "FUTSC_DROME", "id": "Q9W596-1", "name": "Microtubule-associated protein futsch", "aln": "MGDQPKATTTATGGAAGPVPEGDAVMATTNQDALAKGAGDGPAQDAAQEPGQAEHGEPGDGGDGGDDGATDAGASSLPPSEIGGRAPLDTACSDADGGAPSSLAGGIVGPPSPLTGCYLLIVLGEPHSEEHKDNILQHLLKGFLSWDVSDCHVDLEEELN-TITQHAPEGEEARHGERLIQYASENLVTEVLIHPQYNTLIQCMRNLLSSFTRHRHIIHAGYTFSGNGSWILQDGTFSVADFSEAFQEHDVQRVIR--AYADTITMNIHCADAGLWHTLPEKAFARQCRIRINPVDVLDTSSECINGFIDYLAPMVMPTSLRELLETSDVVGNIRFTHPTLYVFPGGQGDAALFGINGFNMLVDGGFNRKACFWDFARHLDRLDAVLMTRLNNSNVQGLGAVVSRKRD------------------AHVYPQIGHFFGNVPDRKGLPSPDGDKDRDPLLIDLFERGHGIVSDLKALDLKPQCCYRNQ----EPVNLYHKVGHGTLDMYVISPARDSKEVKEFLQKWHAGD--QRLFAARDSRDFNFPLQNLVSICALLVWQPANPDDTITRILFPGSTPDFKIQEGLEKLKHLEFMKHSTCTAKSIAPAIQTVTSTRKSLKSAIEATPAPPSASYKTTKFSPVASAALAVQHPQQQDNKAKEAAAAAAAAAAAAASAATIARAKADSMDTDAEPEHEADPEPADTGDEAAPTEQEPEAETEPEPEHEPEAEQDKDVGEEKKVEVLIMKPQQATPAVIAASGKDGVDAASADATPTGKLSKASAKGKADKPRAEVKPVVRSRIDTKPPKSMDRKLAKRDEKKSSPTTTPAARAPVAQNAKPKVLSRPATKSSPSSTPAKSAKEANNRKVLESKQQAARVQATSTVSRRVTSTASERRVQQQAEAKTAATGATQATQRKPISRRPRGVSPSKRAPAPGSPVKQAKPKAADLKKTRLDKGGTTDSSLVSTPSADEATAAKKLQDLTASQELDAEKQRELDDLKEEQEVVREIEAVFSRDEMKRQQHQQIKAELREMPAEGTGDGENEPDEEEEYLIIEKEEVEQYTEDSIVEQESSMTKEEEIQKHQRDSQESEKKRKKSAEEEIEAAIAKVEAAERKARLEGASARQDESELDVEPEQSKIKAEVQDIIATAKDIAKSRTEEQLAKPAEEELSSPTPEEKLSKKTSDTKDDQIGAPVDVLPVNLQESLPEEKFSATIESGATTAPTLPEDERIPLDQIKEDLVIEEKYVKEETKEAEAIVVATVQTLPEAAPLAIDTILASATKDAPKDANAEALGELPDSGERVLPMKMTFEAQQNLLRDVIKTPDEVADLPVHEEADLGLYEKDSQDAGAKSISHKEESAKEEKETDDEKENKVGEIELGDEPNKVDISHVLLKESVQEVAEKVVVIETTVEKKQEEIVEATTVITQENQEDLMEQVKDKEEHEQKIESGIITEKEAKKSASTPEEKETSDITSDDELPAQLADPTTVPPKSAKDREDTGSIESPPTIEEAIEVEVQAKQEAQKPVPAPEEAIKTEKSPLASKETSRPESATGSVKEDTEQTKSKKSPVPSRPESEAKDKKSPFASGEASRPESVAESVKDEAGKAESRRESIAKTHKDESSLDKAKEQESRRESLAESIKPESGIDEKSALASKEASRPESVTDKSKEPSRRESIAESLKAESTKDEKSAPPSKEASRPGSVVESVKDETEKSKEPSRRESIAESAKPPIEFREVSRPESVIDGIKDESAKPESRRDSPLASKEASRPESVLESVKDEPIKSTEKSRRESVAESFKADSTKDEKSPLTSKDISRPESAVENVMDAVGSAERSQPESVTASRDVSRPESVAESEKDDTDKPESVVESVIPASDVVEIEKGAADKEKGVFVSLEIGKPDSPSEVISRPGPVVESVKPESRRESSTEIVLPCHAEDSKEPSRPESKVECLKDESEVLKGSTRRESVAESDKSSQPFKETSRPESAVGSMKDESMSKEPSRRESVKDGAAQSRETSRPASVAESAKDGADDLKELSRPESTTQSKEAGSIKDEKSPLASEEASRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEETRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESAAEKSPLPSKEASRPASVAESVKDEADKSKEESRRESMAESGKAQSIKGDQSPLKEVSRPESVAESVKDDPVKSKEPSRRESVAGSVTADSARDDQSPLESKGASRPESVVDSVKDEAEKQESRRESKTESVIPPKAKDDKSPKEVLQPVSMTETIREDADQPMKPSQAESRRESIAESIKASSPRDEKSPLASKEASRPGSVAESIKYDLDKPQIIKDDKSTEHSRRESLEDKSAVTSEKSVSRPLSVASDHEAAVAIEDDAKSSISPKDKSRPGFVAETVSSPIEEATMEFSKIEVVEKSSLALSLQGGSGGKLQTDSSPVDVAEGDFSHAVASVSTVTPTLTKPAELAQIGAAKTVSSPLDEALRTPSAPEHISRADSPAECASEEIASQDKSPQVLKESSRPAWVAESKDDAAQLKSSVEDLRSPVASTEISRPASAGETASSPIEEAPKDFAEFEQAEKAVLPLTIELKGNLPTLSSPVDVAHGDFPQTSTPTSSPTVASVQPAELSKVDIEKTASSPIDEAPKSLIGCPAEERPESPAESAKDAAESVEKSKDASRPPSVVESTKADSTKGDISPSPESVLEGPKDDVEKSKESSRPPSVSASITGDSTKDVSRPASVVESVKDEHDKAESRRESIAKVESVIDEAGKSDSKSSSQDSQKDEKSTLASKEASRRESVVESSKDDAEKSESRPESVIASGEPVPRESKSPLDSKDTSRPGSMVESVTAEDEKSEQQSRRESVAESVKADTKKDGKSQEASRPSSVDELLKDDDEKQESRRQSITGSHKAMSTMGDESPMDKADKSKEPSRPESVAESIKHENTKDEESPLGSRRDSVAESIKSDITKGEKSPLPSKEVSRPESVVGSIKDEKAESRRESVAESVKPESSKDATSAPPSKEHSRPESVLGSLKDEGDKTTSRRVSVADSIKDEKSLLVSQEASRPESEAESLKDAAAPSQETSRPESVTESVKDGKSPVASKEASRPASVAENAKDSADESKEQRPESLPQSKAGSIKDEKSPLASKDEAEKSKEESRRESVAEQFPLVSKEVSRPASVAESVKDEAEKSKEESPLMSKEASRPASVAGSVKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESVKDEADKSKEESRRESGAEKSPLASKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRDSVAEKSPLASKEASRPASVAESVQDEAEKSKEESRRESVAEKSPLASKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLASKEASRPTSVAESVKDEAEKSKEESSRDSVAEKSPLASKEASRPASVAESVQDEAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDDAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRESVAEKSSLASKKASRPASVAESVKDEAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEADKSKEESRRESGAEKSPLASMEASRPTSVAESVKDETEKSKEESRRESVTEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRESVAEKSPLASKESSRPASVAESIKDEAEGTKQESRRESMPESGKAESIKGDQSSLASKETSRPDSVVESVKDETEKPEGSAIDKSQVASRPESVAVSAKDEKSPLHSRPESVADKSPDASKEASRSLSVAETASSPIEEGPRSIADLSLPLNLTGEAKGKLPTLSSPIDVAEGDFLEVKAESSPRPAVLSKPAEFSQPDTGHTASTPVDEASPVLEEIEVVEQHTTSGVGATGATAETDLLDLTETKSETVTKQSETTLFETLTSKVESKVEVLESSVKQVEEKVQTSVKQAETTVTDSLEQLTKKSSEQLTEIKSVLDTNFEEVAKIVADVAKVLKSDKDITDIIPDFDERQLEEKLKSTADTEEESDKSTRDEKSLEISVKVEIESEKSSPDQKSGPISIEEKDKIEQSEKAQLRQGILTSSRPESVASQPESVPSPSQSAASHEHKEVELSESHKAEKSSRPESVASQVSEKDMKTSRPASSTSQFSTKEGDEETTESLLHSLTTTETVETKQMEEKSSFESVSTSVTKSTVLSSQSTVQLREESTSESLSSSLKVEDSSRRESLSSLLAEKGGIATNTSLKEDTSASASQLEELLVQSEECSSESIVSEIQTSIAQKSNKEIKDARETKVTSQFTTTTSSATKDDSLKETVAEFLATEKIVSAKEAFSTEATKSADDCLKKTTASAVSSTSASQRALFVGTDESRRESLLSQASESRLTHSDPEDEEPADDVDERSSVKESRSKSIATIMMTSIYKPSEDMEPISKLVEEEHEHVEELAQEVTSTSKTTTLLQSSEQSSTTTSSTSKTGASRVESITLTQMDQQTSQSQGDPADRKTPPTAPVSPGVKAMSSTGSAGSVIGAGAGAVAAGGKCESSAASIVSSSGPMSPKDISGKSSPGALTSESQSIPTPLGRESHTDTPESSPKPTSPFPRVSKDELKSLEMQHHSQEQMLAGAAAAAGAECEGDIPELHELRGLECTTALSGSTDKIITTTITTVTKVISADGKEIVTEQKTVTTTDSSEPDSEKVVVTTTRTTSESERDQLLPKEVALLRGLYRASTPGSEDDEDLLLGSPRSATSYELQHSSSGVSKRSDLDADGDESQDDIPPQYGSEEHSTARSILLPRTADPMATSFYGALPDSFDVVMKPSTEPIPIQGAPSGDSQSSESVESSSQTWAGHKFLDQADKDFQRALEEHVQARGAEVMSSVTAKYSYSPSKAEEMEQIVSGTAERQRFPLSDVQRARVAESGFATVGSVASQQQQQEKGGEVEQAVPTTTAVTASTTATASSTGALPKDRLEEWGKPLGLPSPAPLPVEGGADIRTTPKKERRLVATKTRLNNEKNLRRRSESPNKAGKKPAPVYVDLTYVPHNGNSYYAHVDFFKRVRARYYVFSG-----TEPSRQVYDALLEAKQTWEDKELEVTIIPTYDTDVLGYWVAENEELLAKHRIDLSPSASRCTINLQDHETSCSAYRLEF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * :*:: * .* :***.. * :::::* *:****:**:***.:****:*:*** :**:***.:.*****:*:**:*::. .*: *:..::.** : *::* .* ***:: :*.. . .*. :*.. :. *: *.::.: ** **:.*:**:* * ****::.* :****:: ::*** ... : :. :.:: ::.: *.*: **:** **.* :.*.*:****.:*: ** ******:**:*:::...* *.::.. . . ..:* ::. *. .: : : : . *. : :..: : : * ::* ... * . . : ...: . :* :* : :: :. : *: *.: ::.: :*:: ..:..* *:.. ::* : *..:: : *: . :..**:. : .** : : :. * ::: .: :: . :.:. :*:: : * .. . .* : *: . * . * . : : *... .* : : : . . .. .:.. *.: *. : *. :: ..*. . :. . . .*. .. * *::.. :..:. * * ..: :: . : :: *: .. .*. .... : .: . : . : :***.** .*: . .. :. :.. :. :*:*. :. ::::.:.: : :::.. .. : ::. . : * : *:* * ::: :.. .*. . . . * :**. : : . . . : . : .. . . *.. . : .:: * .**: .: : . : : .:.. . . .* . . . : :: . . . .. : . . . . * ::: . . :. ..:. . ... *: : .: . : : . . : : ... . *. ::: . : : : . . . ::* . . . .. .* :. :. : : :..: : :. *: . . . : ... . :. .*: .: *:. . . .. . : : .: . . . . . : . *. :.. : :. . . . . * :: :.:: :. .. : . : . . ... .. :. . . . . : . . .. . .:: : : * . . : : . : . . ... . . : . . :.. : . . . :.. .:. . . . .. . . .. . . *. : . : . . * .: . . : : .: . . : . * : . . :. : :. . . : .* : . : :: . :. :: * . : : :. . : . . : :.. .. . : * * . . . : * . :: . . . . . . * . . . . * .. .. ..: * * .: ..* . :.. ::. *: : . .*::* * * ..:.*. : .* * . * .* * :. ** : : : . . ::: :. : . **: : : : : .: : .: . . .. .*:****:*:*:: .. .. :**:***: ***.** **** * *****.* * .: *:**:***:**:* * :..* : .: : .*:* .: :: * .* ::**", "identical_positions": 252, "similar_positions": 752, "identity": "4.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100426-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P34926-1", "uniprot_id": "MAP1A_RAT", "id": "P34926-1", "name": "Microtubule-associated protein 1A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGVAEFSEYVSETVDVPSPFDLLEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNILVDGGSDRKSCFWKLVRHLDRIDSVLLTHIGADNLPGINGLLQRKVAELEEEQSQGSSSYSDWVKNLISPELGVVFFNVPDKLRLPDASRKAKRS------IEEACLTLQHLNRLGIQAEPLYRVVSNTIEPLTLFHKMGVGRLDMYVLNPVKDSKEMQFLMQKWAGNSKAKTGIVLANGKEAEISVPYLTSITALVVWLPANPTEKIVRVLFPGNAPQNKILEGLEKLRHLDFLRYPVATQKDLAAGAVPANLKPSKIKHRADSK----------------------------------------------ESLKAAPKTAVSKLAKREEVLEEGAKEARSELAKELAKTEKKAKEPSEKPPEKPSKSERVRGE-------------------------------------------------SSEALKAEKRRLIKDKAGKKHLKEKISKLEEKKDK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKKEIKKERKELKKEEGRKEEKKDAKKDEKRKDTKPEVKKLS------------------------------------KPDLKPFTPEVRKTLYKAKAPGRVKVDKGRAARGEKELSSEPRTPPAQKGAAPPAA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VSGHRELALSSPEDLTQDFEELKREERGLLA-----------------EQRDTGLGEKPLPADATE-----------------------------------------QGHPSAAIQVTQ-------------PSGPVLEGE-HVEREKEVVPDSPGDKGSTNRG----------------------------------------PDSGAEVEKEKETWEERKQREAELGPEN-TAAREES----EAEVKEDVIEKAELEEMEETHPSDEEGE-ETKAESFYQKHTQEALKASPKSREALGGRD---------LGFQGKAPEKE-----------TASFLSSLATPAGATEHVSYIQDETIPGYSETEQTISDEEIHDEPDERPAPPRFPTSTYDLSGPEGPGP--FEASQAADSAVPASSSK-------------------------------------------------------TYGAPETELTYPPNMVAAPLAEEEHVSSATSITECDKLSSFATSVAE-------------------------DQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLD--------------------------------YVPSAGTISPTSSLEEDKGFKSPPCEDFSVTGESEKKGETVGRGLSGEKAVGKEEK---YVVTSEKLSGQY--------------------------------------AAVFGAPGHTLPPGEPALG-------------------EVEERCLSPDDSTVKMASPPPSGPPSAAHTPFHQSPVEDKS------------------------------EPRDFQE-DSWGETKHSPGVSKED------------------------------------------------------------------------------SEEQTVKPGPEEGTSE-EGKGPPTRSPQAQDMPVSIAGGQTGCTIQLLPEQDKAIVFETGEAGSNLG-------------AGTLPGEVRTSTEEATEPQKDE--------------------------------VLRFTDQSLSPEDAESLSVLSVVSPD----------------TTKQEATPRSPCSLKEQQPHKDLWPMVS----------------------------------PEDTQSLSFSEESPSKETSLDISSKQLSPESLGTLQFGELNLGKEERGP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VMKAEDDSCHLAPVSIPEPHRATVSPS-------------TDETPAGTLPGGSFSHSALSVDRKHSPGEITGPGGHFMTSDSSLTKSPESLSSPAMED--LAVEWEGKAPG--------KEKEPE----------------------------------------------------------------LKSETRQQKGQILPEKVAVVEQDLIIHQKDGALDEEN----------------------------------------KPGRQQDKTPEQKGRDLDEKDTAAELD-KGPEP-----KEKDLDREDQGQ--RAGPPAEKDKASEQRDTDLQQT-QATEPRDRAQERRDSEEKDKSLELRDRTPEEKDRILVQEDRAPEHSIP--------------EPTQTDRAPDRK-----------------------------GTDDK--EQKEEASEEKEQVLEQKDWALGKEGE-------------TLDQEARTAEQKDETLKE-DKTQGQKSSFVEDKTTTSKETVLDQKSAEKADSVEQQDGAALEKTRA-----------------------------------------------------LGLEE--SPAEGSKAREQEKKYWKEQDVVQGWRETSPTRGEPVGGQKEPVPAWEGKSPEQEVRYWRDR------------------------DITLQQDAYWRELSCDRKVWFPHELDGQGARPRYCEERESTFLD-EGPD-EQEITPLQHTPRSPWTSDFKDFQEPLPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEIISPPASPPE------MTGQRVPSAPGQESPVPDTESTAPMRNEPTTPSWLAEIPPWVPKDRPLPPAPLSPAPAPPTPAPEPHTPVPFSWGLAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREGEGGAGAPDSSSFSPKVPEAGESLATRDTEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGASGDWPPHLSTKEEAAGCNTSAEKETSSPASPQNLQSDTPAFS--------------------------YASLAGPAVPPRQEPDPGPNVEPSITPPAVPPRAPISLSKDLSPPLNGSTVSCSPDRRTPSPKETGRGHWDDGTNDSDLEKG---------------------AREQPEKE--------------------------------------------TRSPSPHHPMPMGHSSLWPETEAYSSLSSDSHLGSVRPSLDFP----------ASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALVPGTPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGGPLLSNLPRPASP---------------------------------------------------------ALSEGSSSEATTPVISSVAERFPPG-----------------LEAAEQSAEGLGSGKESAAHSLWDLTPLSPAPSASLDLAPAP------------APAPAPAPGLPGDLG-----------------------------DGTLPCRPECTGELTK------------------------------------------------------------------------------------------------------------------------KPSPFLSPS--------------------------------------GDHEANGPGETSLNPPGFVTATAEKEE----------------------------------------AEAPHAWERGSWPEGAERSSRPDTLLSSEQPLRPGKSSGGPPCSLSSEVEAGPQGCATDP---------------------------RPHCGELSPSFLNPP---LPPSTDDSDLSTEEAR-----------------------------LAGKGGRRRVGRPGATGGPCPMADETPPTSASDSGSSQS----------------------DSDVPPETEECPSITAEAALDSD--------------------------EDGDFLPVDKAGGVSG---THHPRP------GHDPPPTPLPDPRPSPPRP---------------------------------------------------------------------------------------DVCMADPEGLSSESGRVERLREK----GRPGRRAPGRAKPASPARRLD-------------------------------------------------------------------------------IRGKRSPTPGKGPVDRTSRTVPRPRS-----------------------------------------------------------------------------------TPSQVTSAEEKDGHSPMSKGLVNGLKAGSTALGSKGG-----------------------------------------------------------------SGPPVYVDLAYIPNHCSGKTADQDFFRRVRASYYVVSGNDPANGEPSRAVLDALLEGKAQWGEN-LQVTLIPTHDTEVTREWYQQTHEQQQQLNVLVLASSS----TVVMQDESFPACKIEF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYR6-1", "uniprot_id": "MAP1A_MOUSE", "id": "Q9QYR6-1", "name": "Microtubule-associated protein 1A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGVAEFSEYVSETVDVPSPFDLLEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNILVDGGSDRKSCFWKLVRHLDRIDSVLLTHIGADNLPGINGLLQRKVAELEEEQSQGSSSYSDWVKNLISPELGVVFFNVPDKLRLPDASRKAKRS------IEEACLTLQHLNRLGIQAEPLYRVVSNTIEPLTLFHKMGVGRLDMYVLNPVKDSKEMQFLMQKWAGNSKAKTGIVLANGKEAEISVPYLTSITALVVWLPANPTEKIVRVLFPGNAPQNKILEGLEKLRHLDFLRYPVATQKDLAAGAVPANLKPSKIKHRADSK----------------------------------------------ESLKAAPKTAMSKLAKREEVLEEGAKEARSELAKELAKSEKKAKEPSEKPPEKPSKPERVRTE-------------------------------------------------SSEALKAEKRKLIKDKVGKKHLKEKISKLEEKRDK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKKEIKKERKELKKEEGRKEEKKDAKKDEKRKDTKPELKKFS------------------------------------KPDLKPFTPEVRKTLYKAKAPGRLKVDKGRAARGEKELSSEPRTPPAQKGAAPPPA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASGHRELALSSPEDLTQDFEELKREERGLLA-----------------EPRDTELGEKPLPADASE-----------------------------------------QGRPSTAIQVTQ-------------PPASVLEQE-QVEREKEVVPDFPEDKGSKNRA----------------------------------------PDSGAEVEREKETWEERKPREAELTPENIAAAREES----EPEVKEDVIEKAELEEMEEVHPSDEEEE-ETKAESFYQKHMQEALKVIPKGREALGGRE---------LGFQGKAPEKE-----------TASFLSSLATPAGAAEHVSYIQDETIPGYSETEQTISDEEIHDEPDERPAPPRFPTSTYDLSGPEGPGP--FEASQSAESAVPASSSK-------------------------------------------------------TYGAPETELTYPPNMVAAPLAEEEHVSSATSITECDKLSSFATSVAE-------------------------DQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLD--------------------------------YVPSAGTISPTSSLEEDKGFKSPPCEDFSVTGESEKKGESVGRGLTGEKAVGKEEK---NVTTSEKLSSQY--------------------------------------AAVFGAPGHALHPGEPALG-------------------EVEERCLSPDDSTVKMASPPPSGPPSAAHTPFHQSPVEEKS------------------------------EPQDFQE-DSWGDTKHAPGVSKED------------------------------------------------------------------------------AEEQTVKPGPEEAMSE-EGKVPLSRSPQAQDTLGSLAGGQTGCTIQLLPEQDKAVVFETGEAGAASG-------------AGSLPGEVR--TQEPAEPQKDE--------------------------------LLGFTDQSFSPEDAESLSVLSVVSPD----------------TAKQEATPRSPCTPKEQQLHKDLWPMVS----------------------------------PEDTQSLSFSEESPSKETSLDISSKQLSPESLGTLQFGELSLGKEEKGP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVKAEDNSCHLAPVSIPEPHTATVSPPTD---EAAGEAGLTDESPAGNLPGSSFSHSALSGDRKHSPGEITGPGGHFMTSDSSLTKSPESLSSPAMED--LAMEWGGKAPGSEDRATEQKEKELE----------------------------------------------------------------RKSETLQQKDQILSEKAALVQRDSVMHQKDEALDEEN----------------------------------------KPGGQQDKTSEQKGRDLDKKDTAVELG-KGPEP-----KGKDLYLEDQG-------LAEKDKALEQRGAALQQT-QAPEPRARAQEHRDLEQKDEHLELRDKTPEEKDKVLVLEDRAPEHIIP--------------QPTQTDRAPEHR-----------------------------SKVDK--EQKDEASEEKEQVLEQKDWAREKEGA-------------ALDQDNRAAGQKDGTLKE-DKTQGQKSSFLEDKSTTPKEMTLDQKSPEKAKGVEQQDGAVPEKTRA-----------------------------------------------------LGLEE--SPEEEGKAREQEEKYWKEQDVVQGWRETSPTRGE-------PVPAWEGKSPEQEVRYWRDR------------------------DITLQQDAYWKELSCERKVWFPHELDGQGARPRYSEERESTFLD-EGPN-EQEITPLQHTPRSPWASDFKDFQEPLPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEIISPPASPPE------MTGQRVPSAPGQESPVPDTKSTPPTRNEPTTPSWLAEIPPWVPKDRPLPPAPLSPAPAPPTPAPDPHAPAPFSWGIAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREGEGGAGAPDSSSFSSKVPEVTESHTTRDAEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGASGDWPPHLSTKEEAAGRNKSAEKELSSAVSPPNLHSDTPTFS--------------------------YASLAGPTIPPRQEPEPGPNVEPSFTPPAVPPRAPISLSQDPSPPLNGSTTSCGPDRRTPSPKEAGRSHWDDGTNDSDLEKG---------------------AREQPEKE--------------------------------------------TQSPSPHHPMPVGHPSLWPETEAHSSLSSDSHLGPVRPSLDFP----------ASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALVPGTPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASP---------------------------------------------------------ALSEGSSSEATTPVISSVAERFPPG-----------------LEVAEQSSGELGPGNEPAAHSLWDLTPLSPAPLASRDLAPAP------------APAPAPS--LPGNLG-----------------------------DGTLSCRPECSGELTK------------------------------------------------------------------------------------------------------------------------KPSPFLSHS--------------------------------------GDHEANGPGETSLNPPGFATATAEKEE----------------------------------------AEALHAWERGSWPEGAERSSRPDTLLSSEQ--RPGKSSGGPPCSLSSEVEAGPQGCATDP---------------------------RPHCGELSPSFLNPP---LPPSTDDSDLSTEEAR-----------------------------LAGKGGRRRAGRPGATGGPCPMADETPPTSASDSGSSQS----------------------DSDVPPETEECPSITAEAALDSD--------------------------EDGDFLPVDKAGGVSG---THHPRP------GHDPPPAPLPDPRPPPPRP---------------------------------------------------------------------------------------DVCMADPEGLSSESGRVERLREKV--QGRPGRKAPGRAKPASPARRLD-------------------------------------------------------------------------------IRGKRSPTPGKGPVDRTSRALPRPRS-----------------------------------------------------------------------------------TPSQVTS-EEKDGHSPMSKGLVNGLKAGSTALGSKGS-----------------------------------------------------------------SGPPVYVDLAYIPNHCSGKTADQDFFRRVRASYYVVSGNDPANGEPSRAVLDALLEGKAQWGEN-LQVTLIPTHDTEVTREWYQQTHEQQQQLNVLVLASSS----TVVMQDESFPACKIEF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P78559-1", "uniprot_id": "MAP1A_HUMAN", "id": "P78559-1", "name": "Microtubule-associated protein 1A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDGVAEFSEYVSETVDVPSPFDLLEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNILVDGGSDRKSCFWKLVRHLDRIDSVLLTHIGADNLPGINGLLQRKVAELEEEQSQGSSSYSDWVKNLISPELGVVFFNVPEKLRLPDASRKAKRS------IEEACLTLQHLNRLGIQAEPLYRVVSNTIEPLTLFHKMGVGRLDMYVLNPVKDSKEMQFLMQKWAGNSKAKTGIVLPNGKEAEISVPYLTSITALVVWLPANPTEKIVRVLFPGNAPQNKILEGLEKLRHLDFLRYPVATQKDLASGAVPTNLKPSKIKQRADSK----------------------------------------------ESLKATTKTAVSKLAKREEVVEEGAKEARSELAKELAKTEKKAKESSEKPPEKPAKPERVKTE-------------------------------------------------SSEALKAEKRKLIKDKVGKKHLKEKISKLEEKKDK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKIS------------------------------------KPDLKPFTPEVRKTLYKAKVPGRVKIDRSRAIRGEKELSSEPQTPPAQKGTVPLPT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ISGHRELVLSSPEDLTQDFEEMKREERALLA-----------------EQRDTGLGDKPFPLDTAE-----------------------------------------EGPPSTAIQGTP-------------PSVPGLGQEEHVMKEKELVPEVPEEQGSKDRG----------------------------------------LDSGAETEEEKDTWEEKKQREAERLPDR-TEAREES----EPEVKEDVIEKAELEEMEEVHPSDEEEEDATKAEGFYQKHMQEPLKVTPRSREAFGGRE---------LGLQGKAPEKE-----------TSLFLSSLTTPAGATEHVSYIQDETIPGYSETEQTISDEEIHDEPEERPAPPRFHTSTYDLPGPEGAGP--FEASQPADSAVPATSGK-------------------------------------------------------VYGTPETELTYPTNIVAAPLAEEEHVSSATSITECDKLSSFATSVAE-------------------------DQSVASLTAPQTEETGKSSLLLDTVTSIPSSRTEATQGLD--------------------------------YVPSAGTISPTSSLEEDKGFKSPPCEDFSVTGESEKRGEIIGKGLSGERAVEEEEEETANVEMSEKLCSQYG-------------------------------------TPVFSAPGHALHPGEPALG-------------------EAEERCLSPDDSTVKMASPPPSGPPSATHTPFHQSPVEEKS------------------------------EPQDFQEADSWGDTKRTPGVGKED------------------------------------------------------------------------------AAEETVKPGPEEGTLEKEEKVPPPRSPQAQEAPVNIDEGLTGCTIQLLPAQDKAIVFEIMEAGEPTGP---------ILGAEALPGGLRTLPQEPGKPQKDE--------------------------------VLRYPDRSLSPEDAESLSVLSVPSPD----------------TANQEPTPKSPCGLTEQYLHKDRWPEVS----------------------------------PEDTQSLSLSEESPSKETSLDVSSKQLSPESLGTLQFGELNLGKEEMGH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LMQAEDTSHHTAPMSVPEPHAATASPPTDGTTRYSAQTDITDDSLDRKSPASSFSHSTPSGNGKYLPGAITSPDEHILTPDSSFSKSPESLPGPALED--IAIKWEDKVPGLKDRTSE-QKKEPE----------------------------------------------------------------PKDEVLQQKDKTLEHKEVVEPKDTAIYQKDEALHVKN----------------------------------------EAVKQQDKALEQKGRDLEQKDTALEQKDKALEP-----KDKDLEEKDKALEQKDKIPEEKDKALEQKDTALEQKDKALEPKD-----KDLEQKDRVLEQKEKIPEEKDKALDQKVRSVEHKAP--------------EDTVAEMKDRDL-----------------------------EQTDKAPEQKHQAQEQKDKVSEKKDQALEQKYW-------------ALGQKDEALEQNIQALEENHQTQEQESLVQEDK--TRKPKMLEEKSPEKVKAMEEKLEALLEKTKA-----------------------------------------------------LGLEE--SLVQEGRAREQEEKYWRGQDVVQEWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGRE-----------------------DVALEQDTYWRELSCERKVWFPHELDGQGARPHYTEERESTFLD-EGPDDEQEVPLREHATRSPWASDFKDFQESSPQKGLEVERWLAESPVGLPPEEEDKLTRSPFEIISPPASPPE------MVGQRVPSAPGQESPIPDPKLMPHMKNEPTTPSWLADIPPWVPKDRPLPPAPLSPAPGPPTPAPESHTPAPFSWGTAEYDSVVAAVQEGAAELEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKVPEASKSHATTEPEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPLGAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDTPTFS--------------------------YAALAGPTVPPR--PEPGPSMEPSLTPPAVPPRAPI-LSKGPSPPLNGNILSCSPDRRSPSPKESGRSHWDDSTSDSELEKG---------------------AREQPEKE--------------------------------------------AQSPSPPHPIPMGSPTLWPETEAHVSPPLDSHLGPARPSLDFP----------ASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAFSGDRALALAPGPPTRTRHDEYLEVTKAPSLDSSLPQLPSPSSPGAPLLSNLPRPASP---------------------------------------------------------ALSEGSSSEATTPVISSVAERFSPS-----------------LEAAEQESGELDPGMEPAAHSLWDLTPLSPAPPASLDLALAP------------APS------LPGDMG-----------------------------DGILPCHLECSEAATE------------------------------------------------------------------------------------------------------------------------KPSPFQVPS--------------------------------------EDCAANGPTETSPNPPGPAPAKAENEE----------------------------------------AAACPAWERGAWPEGAERSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEP---------------------------RPHRGELSPSFLNPP---LPPSIDDRDLSTEEVR-----------------------------LVGRGGRRRVGGPGTTGGPCPVTDETPPTSASDSGSSQS----------------------DSDVPPETEECPSITAEAALDSD--------------------------EDGDFLPVDKAGGVSG---THHPRP------GHDPPPLPQPDPRPSPPRP---------------------------------------------------------------------------------------DVCMADPEGLSSESGRVERLREKEKVQGRVGRRAPGKAKPASPARRLD-------------------------------------------------------------------------------LRGKRSPTPGKGPADRASRAPPRPRS-----------------------------------------------------------------------------------TTSQVTPAEEKDGHSPMSKGLVNGLKAGPMALSSKGS-----------------------------------------------------------------SGAPVYVDLAYIPNHCSGKTADLDFFRRVRASYYVVSGNDPANGEPSRAVLDALLEGKAQWGEN-LQVTLIPTHDTEVTREWYQQTHEQQQQLNVLVLASSS----TVVMQDESFPACKIEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IY35-1", "uniprot_id": "A0AC58IY35_DANRE", "id": "A0AC58IY35-1", "name": "", "aln": "--------------------MSCRVCVLRSQSCVLFGQSDGGKQRVSSALLALTVRSGQLAAVVMEMSAGPSSVRGAVPAESPPRGSLVAAAEDDEH-----REQPLPEQTARSGDFYMLIVIGEIATEQQLQTARLHIERGIRSWDISVSECDLDQQLQLFITRHSAQFSAEVRGQRTLQHKSDVLETVVLVNPSEDTVISEIHCLVSDPAVH-KLLVLSGQSSDQGDLVLQTGVFSHQTFLRVFAEPGVSHLLGKASSGQRASLTVSCRSDAGWSSLGQQQRIRELLNYTLNPEPILPKMEGVTEFTEYISETVDVPSPFDLLEPPTSGGFLKLSKPCCYIFPGGRGDSALFAVNGFNILIDGGSDRRSCFWKLVRHLDRIDSVLLTHIGADNLPGINGLLQRKVAEQEEEQSQGSTTYSDWMKNLISPELGVVFFNVPEKLRTSESNLKVKRS------IEEASLTLQYLNKLGIKPEPLFRVVSNTIEPITLFHKMGVGRLDMFVLNPVKDSKEMQFLMQKWAGNSKAKTGIILPNGKEGEISVPYLTSITALVVWLPASPTEKIVRVLFPGNAPQNKILEGLEKLKHLDFLRYPVATQKDINSGVSPSAVKQTKLKQRTDSK----------------------------------------------ESLKSSPKTHTPAKPSKKETDEH----------EDVSVVETKSDSVKENKVEKKEEKKHTKSL-------------------------------------------------KPKAEVTEKKKLLKEKPLKKHPKERLSKMDEKKDK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKREIKKEKRVIKQDDS---VKKDEKKMKAKDSSKPELRKIT------------------------------------KPELKPFTPEVRKTLHKAKTQGKPKSIKKKPTTAKAEIAEITAEPVAEK--TEPEK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QENGTVEDISAPEDLTKDLNKIKPTEVTSQS-----------------ESPKSDLTVSELPAEKDI-----------------------------------------EPSKSAEDKVGETDMVEQKTKVEEVSASAGIKEVSSAAVKEKDEPQTSEIEKFEDEG----------------------------------------AAIEDEDEEEIDIQPVKKKTDDEEEEDMGIGDEEDEGPAKETKDLEGVDRKHEVEEMEKQKQVEERRIEAEDEQFEEEDVIEKAELEEAEDLDAIADEE---------IKELSPEKVKDEEDAYMSNVGGVTAGITSTAQGAAAAENLSYIQDETIPGYSETEQTISDEEIHEEAEDRIPHLQYEVGSYDVSVPDQPGS--FDAMHGMREMQAAAMGNGTSKV--------------------------------------------------FMGAQEPAISIYTSILAAPLAEEEHVSSATSITEYDKLSSLPTSIAE-------------------------DQSVASVTAPQTEDTGKSSLVLDTVQPIT--QTEATQGKD--------------------------------YLHSAGTISPTSSLEEDKCFKSSPSDESPPLPLEGKTEGIEMAAHYDDEEEDEYDQTPNVDISLEKLQEGYASPDKLEHKDKEMDKPKSPVPLVPDMSTFEKSSIPETEKASVASPKEDMSFKEQAILSSSSHSVSKLPVSEASVYPEVEDRCVSPDDSTVKMASPTHSGPPSASHSPLRMSPVEGKDK--------VLLKDTHQEQGVPISPTEFKFEKKNEKQESDILDEKEKPQAEKEEKNIIQKAVTAPSPLVDDVLAKKESESVPPPKDVSDTKEIPDPSVEKKVEVKEGLKEAEDKDSKLSDDHDVEETCDLKLSTEKKEQEKQKEGEGDAEEKYNDKDEFLKYAEVTDKGAGKSEVEKATQPSKEDFDKKNANEEFQDKGY---------LAVLEGLEIEKQVKQVEEIQPEKPE--------------------------------ISSKLDKESKEKDVTGASCQFLESLD----------------IKAETSTSPESTKIDTETHGTKETDIKTKPEKTSQQKPESIDTTTEQVALTETDSFVSIAQFTEDTDSLKSKTQQLGEKTDVTLKKEKAESKSVTDLTFESITTAAKEHDKS-------------------------------------------------------------------------------------------------------------------------------------------------------WNENVEEVKSSTQVQISPLKTDVQSTEMHVDMSIMEKDISSKDDEEFKLKTTQEMEEHISGEISPETKMTSEKDEVLEQKLIEETQNTQQLQKADISSKAEPQMSHSTVSEDTEDGHQISQDIEKSVEDIKCKTQISISENLDFPPTVDQ--ESKAKKADLSQDQVSLVESEKLDLS----------------------------------------------------------------AEGDQECKKAVEIPSKPDEESIECQIYEKKDELSISKSVFEPEVQSEFQPVTSDKEGLHTKEDESNKVTFVKSEQSVEFEEISSKPYESKYKFVEETQLQVSKDQSVPESSITVAKKDQLYEEKQTEETVTKAPQSSMETNVPPDTKQEFEATSVEDKKTELILSESKTVDSKAEHDTLETETKSEITTVEDKTTESKVS--------------KETEEKILKEDASKLVLDEPDTKMDLGAKEKSLVENLERTRKTSDLDCKEKEETKEHKEDINIDTSLQETDTFQSSD-----IGFKLNLDYKEKFIEETPSTVEKTKDGKSAFETTFPTKFSDEDESTEEDEGDAVCMGGAGSRPLSVEPWKS-----------------------------------------------------EELKENISAQPSEPSIQKEEIIAHSEELTKGCSEKSTEPEECKVDATSIVLSTANTSSKAVSEILTETKP---------TSITLLCSDSQTSGVDGQHETLFSKGAAKPEKEAEREWEGEREVASPVLESHSDFQKSDGADEKCSEKAESERMKSNDKVTYEVEKESYEASKYEPYEKPISKDSDKEREEEDQYPGMDRDLDYIRKTSQA------MELGATCSVEEHSDDEPVSFSKVDYQTSPSIYSSQSAYSEQDNKDLYQEEELVREERLDTSVDSSSTYESKDTLAAGSSFCASSDTQDISEKLEREEKEKEKEDTHSSLLSKLDGSHVQLSDIEPCTSASSFSKPDVQDRDHRRDQVEETMATPHLEDLDKTKPPLTQDFTPQGLLTSSQDQSVQGLTTSSASAYDENKTGSTISGEGKDKNKLGSDDSKDDPFSSGRYSPPEKD-----------------LLPARVLPEDPCTATPGSSGQSVNVDDNVLAFECTAKTDLVASKPLVVSTEEEECMVRSQKIFAEEEDDFEDEEEEDASDLDIEKG---------------------ARELSEKESKAVFDTTSASKSPEGKEKDSVSSLVYGGTAEVPQTGKIVDSSTDKTESLTTKLSSVQGEQYEVIDKQFEKSKEEDTSSVQSETSKP----------SDDKHEPQRTDKKPEVSESLTATQAPMSDGTYSSSSSISYSSSTSASYSTGQHIGDGLDTHINVPSFQLRSDGDTVSYEYSSLKEEESPT--------------------------------------------MDLPCLKKDEYMEVSDRMTHATTTAESISSLARFSPLSPLEESKSFLQDQISSAEEKSEEDMSSIKSDKDHVSDPKHVEPPFSKMPESETSKHAAQ------------TTEVASTTSLKFEIAPLEKADSKEKHSEEKSSDDEPENNKSDFEEGTLPCRIECDKSSSSEQHTDANVFSTKTLHSFELKCSSEPTEMASSQNVPVMACGTLSTSTLSEQIVKQEWEEMSEKIKDLPEKVEERFDMKEETLSQAKCEEVIVKHKEIEDEQIHPEKKCDVRSEKMGEILDGKKSENKSES--------------------------------------EGKPKESEEKEEVKQAEIVVEKESKEKDKESKKQTEEIIMEKYSKNVPESSQHTAISSTMEHEDIVCLKAPPGYGEDVYEDIDREESDEEREVKYDSKERPSSPPSGAQACYAEVSKKADEGFTRPSDLSMEATSSHSP------------SLFKHRKGDISPSFINPSPHDLSSEEGDDDARSDHSRDDDGDEREQHSVKRRSHKQQHHHPQSRQEEGKEGSHSIMGGTSTGHGIMLAGEETPPTSLSESLPSQS----------------------DSDVPPETEECPSITAEGNLDSD--------------------------EDAEHLPVDKMSAAGGSGGSHHSSSP----RSHDPPPIPMKDPLPHPPHP---------------------------------------------------------------------------------------DVCMIDPEALLNGQIHTERPVKKDLKTNRGLRKTLG--KSASPARKGD-------------------------------------------------------------------------------AKTRRSTTPVKQTSKDSSPHTLKRKDSE--------------------------------------------------------------------------------KTFRLTKMSETEGSRGDSGRGLVNGVKSNAASNLKSNAGTP--------------------------------------------------------------PGPPIYVDLAYIPNHCSAKNVDQEFFKRVRAAYYVVSGNDPGSGEPSRAVLDALLEGKAQWGTN-LQVTLIPTHDTEVTRDWYQQTHEKQQDLNIMVLASSS----TVVMQDESFPACKIEF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W596-1", "uniprot_id": "FUTSC_DROME", "id": "Q9W596-1", "name": "Microtubule-associated protein futsch", "aln": "MGDQPKATTTATGGAAGPVPEGDAVMATTNQDALAKGAGDGPAQDAAQEPGQAEHGEPGDGGDGGDDGATDAGASSLPPSEIGGRAPLDTACSDADGGAPSSLAGGIVGPPSPLTGCYLLIVLGEPHSEEHKDNILQHLLKGFLSWDVSDCHVDLEEELN-TITQHAPEGEEARHGERLIQYASENLVTEVLIHPQYNTLIQCMRNLLSSFTRHRHIIHAGYTFSGNGSWILQDGTFSVADFSEAFQEHDVQRVIR--AYADTITMNIHCADAGLWHTLPEKAFARQCRIRINPVDVLDTSSECINGFIDYLAPMVMPTSLRELLETSDVVGNIRFTHPTLYVFPGGQGDAALFGINGFNMLVDGGFNRKACFWDFARHLDRLDAVLMTRLNNSNVQGLGAVVSRKRD------------------AHVYPQIGHFFGNVPDRKGLPSPDGDKDRDPLLIDLFERGHGIVSDLKALDLKPQCCYRNQ----EPVNLYHKVGHGTLDMYVISPARDSKEVKEFLQKWHAGD--QRLFAARDSRDFNFPLQNLVSICALLVWQPANPDDTITRILFPGSTPDFKIQEGLEKLKHLEFMKHSTCTAKSIAPAIQTVTSTRKSLKSAIEATPAPPSASYKTTKFSPVASAALAVQHPQQQDNKAKEAAAAAAAAAAAAASAATIARAKADSMDTDAEPEHEADPEPADTGDEAAPTEQEPEAETEPEPEHEPEAEQDKDVGEEKKVEVLIMKPQQATPAVIAASGKDGVDAASADATPTGKLSKASAKGKADKPRAEVKPVVRSRIDTKPPKSMDRKLAKRDEKKSSPTTTPAARAPVAQNAKPKVLSRPATKSSPSSTPAKSAKEANNRKVLESKQQAARVQATSTVSRRVTSTASERRVQQQAEAKTAATGATQATQRKPISRRPRGVSPSKRAPAPGSPVKQAKPKAADLKKTRLDKGGTTDSSLVSTPSADEATAAKKLQDLTASQELDAEKQRELDDLKEEQEVVREIEAVFSRDEMKRQQHQQIKAELREMPAEGTGDGENEPDEEEEYLIIEKEEVEQYTEDSIVEQESSMTKEEEIQKHQRDSQESEKKRKKSAEEEIEAAIAKVEAAERKARLEGASARQDESELDVEPEQSKIKAEVQDIIATAKDIAKSRTEEQLAKPAEEELSSPTPEEKLSKKTSDTKDDQIGAPVDVLPVNLQESLPEEKFSATIESGATTAPTLPEDERIPLDQIKEDLVIEEKYVKEETKEAEAIVVATVQTLPEAAPLAIDTILASATKDAPKDANAEALGELPDSGERVLPMKMTFEAQQNLLRDVIKTPDEVADLPVHEEADLGLYEKDSQDAGAKSISHKEESAKEEKETDDEKENKVGEIELGDEPNKVDISHVLLKESVQEVAEKVVVIETTVEKKQEEIVEATTVITQENQEDLMEQVKDKEEHEQKIESGIITEKEAKKSASTPEEKETSDITSDDELPAQLADPTTVPPKSAKDREDTGSIESPPTIEEAIEVEVQAKQEAQKPVPAPEEAIKTEKSPLASKETSRPESATGSVKEDTEQTKSKKSPVPSRPESEAKDKKSPFASGEASRPESVAESVKDEAGKAESRRESIAKTHKDESSLDKAKEQESRRESLAESIKPESGIDEKSALASKEASRPESVTDKSKEPSRRESIAESLKAESTKDEKSAPPSKEASRPGSVVESVKDETEKSKEPSRRESIAESAKPPIEFREVSRPESVIDGIKDESAKPESRRDSPLASKEASRPESVLESVKDEPIKSTEKSRRESVAESFKADSTKDEKSPLTSKDISRPESAVENVMDAVGSAERSQPESVTASRDVSRPESVAESEKDDTDKPESVVESVIPASDVVEIEKGAADKEKGVFVSLEIGKPDSPSEVISRPGPVVESVKPESRRESSTEIVLPCHAEDSKEPSRPESKVECLKDESEVLKGSTRRESVAESDKSSQPFKETSRPESAVGSMKDESMSKEPSRRESVKDGAAQSRETSRPASVAESAKDGADDLKELSRPESTTQSKEAGSIKDEKSPLASEEASRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEETRRESVAEKSPLPSKEASRPASVAESIKDEAEKSKEESRRESAAEKSPLPSKEASRPASVAESVKDEADKSKEESRRESMAESGKAQSIKGDQSPLKEVSRPESVAESVKDDPVKSKEPSRRESVAGSVTADSARDDQSPLESKGASRPESVVDSVKDEAEKQESRRESKTESVIPPKAKDDKSPKEVLQPVSMTETIREDADQPMKPSQAESRRESIAESIKASSPRDEKSPLASKEASRPGSVAESIKYDLDKPQIIKDDKSTEHSRRESLEDKSAVTSEKSVSRPLSVASDHEAAVAIEDDAKSSISPKDKSRPGFVAETVSSPIEEATMEFSKIEVVEKSSLALSLQGGSGGKLQTDSSPVDVAEGDFSHAVASVSTVTPTLTKPAELAQIGAAKTVSSPLDEALRTPSAPEHISRADSPAECASEEIASQDKSPQVLKESSRPAWVAESKDDAAQLKSSVEDLRSPVASTEISRPASAGETASSPIEEAPKDFAEFEQAEKAVLPLTIELKGNLPTLSSPVDVAHGDFPQTSTPTSSPTVASVQPAELSKVDIEKTASSPIDEAPKSLIGCPAEERPESPAESAKDAAESVEKSKDASRPPSVVESTKADSTKGDISPSPESVLEGPKDDVEKSKESSRPPSVSASITGDSTKDVSRPASVVESVKDEHDKAESRRESIAKVESVIDEAGKSDSKSSSQDSQKDEKSTLASKEASRRESVVESSKDDAEKSESRPESVIASGEPVPRESKSPLDSKDTSRPGSMVESVTAEDEKSEQQSRRESVAESVKADTKKDGKSQEASRPSSVDELLKDDDEKQESRRQSITGSHKAMSTMGDESPMDKADKSKEPSRPESVAESIKHENTKDEESPLGSRRDSVAESIKSDITKGEKSPLPSKEVSRPESVVGSIKDEKAESRRESVAESVKPESSKDATSAPPSKEHSRPESVLGSLKDEGDKTTSRRVSVADSIKDEKSLLVSQEASRPESEAESLKDAAAPSQETSRPESVTESVKDGKSPVASKEASRPASVAENAKDSADESKEQRPESLPQSKAGSIKDEKSPLASKDEAEKSKEESRRESVAEQFPLVSKEVSRPASVAESVKDEAEKSKEESPLMSKEASRPASVAGSVKDEAEKSKEESRRESVAEKSPLPSKEASRPASVAESVKDEADKSKEESRRESGAEKSPLASKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRDSVAEKSPLASKEASRPASVAESVQDEAEKSKEESRRESVAEKSPLASKEASRPASVAESIKDEAEKSKEESRRESVAEKSPLASKEASRPTSVAESVKDEAEKSKEESSRDSVAEKSPLASKEASRPASVAESVQDEAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDDAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRESVAEKSSLASKKASRPASVAESVKDEAEKSKEESRRESVAEKSPLASKEASRPASVAESVKDEAEKSKEESRRESVAEKSPLPSKEASRPTSVAESVKDEADKSKEESRRESGAEKSPLASMEASRPTSVAESVKDETEKSKEESRRESVTEKSPLPSKEASRPTSVAESVKDEAEKSKEESRRESVAEKSPLASKESSRPASVAESIKDEAEGTKQESRRESMPESGKAESIKGDQSSLASKETSRPDSVVESVKDETEKPEGSAIDKSQVASRPESVAVSAKDEKSPLHSRPESVADKSPDASKEASRSLSVAETASSPIEEGPRSIADLSLPLNLTGEAKGKLPTLSSPIDVAEGDFLEVKAESSPRPAVLSKPAEFSQPDTGHTASTPVDEASPVLEEIEVVEQHTTSGVGATGATAETDLLDLTETKSETVTKQSETTLFETLTSKVES-----KVEVLESSVKQVEEKVQTSVKQAETTVTDSLEQLTKKSSEQLTEIKSVLDTNFEEVAKIVADVAKVLKSDKDITDIIPDFDERQLEEKLKSTADTEEESDKSTRDEKSLEISVKVEIESEKSSPDQKSGPISIEEKDKIEQSEKAQLRQGILTSSRPESVASQPESVPSPSQSAASHEHKEVELSESHKAEKSSRPESVASQVSEKDMKTSRPASSTSQFSTKEGDEETTESLLHSLTTTETVETKQMEEKSSFESVSTSVTKSTVLSSQSTVQLREESTSESLSSSLKVEDSSRRESLSSLLAEKGGIATNTSLKEDTSASASQLEELLVQSEECSSESIVSEIQTSIAQKSNKEIKDARETKVTSQFTTTTSSATKDDSLKETVAEFLATEKIVSAKEAFSTEATKSADDCLKKTTASAVSSTSASQRALFVGTDESRRESLLSQASESRLTHSDPEDEEPADDVDERSSVKESRSKSIATIMMTSIYKPSEDMEPISKLVEEEHEHVEELAQEVTSTSKTTTLLQSSEQSSTTTSSTSKTGASRVESITLTQMDQQTSQSQGDPADRKTPPTAPVSPGVKAMSSTGSAGSVIGAGAGAVAAGGKCESSAASIVSSSGPMSPKDISGKSSPGALTSESQSIPTPLGRESHTDTPESSPKPTSPFPRVSKDELKSLEMQHHSQEQMLAGAAAAAGAECEGDIPELHELRGLECTTALSGSTDKIITTTITTVTKVISADGKEIVTEQKTVTTTDSSEPDSEKVVVTTTRTTSESERDQLLPKEVALLRGLYRASTPGSEDDEDLLLGSPRSATSYELQHSSSGVSKRSDLDADGDESQDDIPPQYGSEEHSTARSILLPRTADPMATSFYGALPDSFDVVMKPSTEPIPIQGAPSGDSQSSESVESSSQTWAGHKFLDQADKDFQRALEEHVQARGAEVMSSVTAKYSYSPSKAEEMEQIVSGTAERQRFPLSDVQRARVAESGFATVGSVASQQQQQEKGGEVEQAVPTTTAVTASTTATASSTGALPKDRLEEWGKPLGLPSPAPLPVEGGADIRTTPKKERRLVATKTRLNNEKNLRRRSESPNKAGKKPAPVYVDLTYVPHNGNSYYAHVDFFKRVRARYYVFSG-----TEPSRQVYDALLEAKQTWEDKELEVTIIPTYDTDVLGYWVAENEELLAKHRIDLSPSASRCTINLQDHETSCSAYRLEF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * :*:: * .* :***.. * :::::* *:****:**:***.:****:*:*** :*::***.:.*****:*:**:*::. .*: *:..::.** : *::* .* ***:: .... . .*. :*.. :. *: *.::.: :* **:.*:**:* * ***:*:.*.:****:: ::*** ... : : :.:: ::.: *.** **:** **.* :.*.*:****.:*: ** ******:**:*:::...* *.: .. . . ..:* ::. : :: . . . *. .: : * :.. .* *: : :: : ... :* : :::.: .* *. *: :: :* **.*::: . :: *:: : . :.. :.* :: . :*: . :..**:. : .** .: : . . .: *::. . .* . . *** ::.:. : * : : . . :* : . : .. . . ::. *. . : ... * * . : : . .* . .. : .: .: * : . .:. . : :. .. . . .: : :. * *:. * ::. . ..**:: :. .. : : : *:. *: . ::* . : .: . :: :: : .*..: **: : . .* .* .* *:* ... .. ::. .*: ::: . : ...:* .**:*. .* .: . ... . * :. .: *.: . : . : . . *: .. .. :.* * *.*.:.: : . :. :. :: :. * ** : :. : ::. : . : . ::. . * . : : : :*.: * : ::. . .: * : * : . .. . : :*..: :. .:: : ... . *: : . . . . :* . . . . . . . . .. * : *:: : : . . : : . . : .: : * . .*. .. : . : : : .. . . .. * .: :.: . : . . . . : * . . : : . : . * : . . . :.: ... . . . . :::. .. . . ::. . . : :: :* : :.* : :. : *.*. : . : . : : . .:: : .. . :* . . : . . . : . * : :: . * . . :* .: . .: .. : : . . . ... * . .. . . .. : * . .. .. . . : . :. . . . . . :* .. . : :.. . . : .. .. .: :. . : : . . .. : . . .: .. .: .. . . . . :: . ::. : **. :. *.. :: * . : . :. . . . . . . *: . : .. : * : : . . : . * * . .: ** ::: : .*. : :.. : *: : .:.. . * :. . : : : . :. : * :. : . * . . . . . :: * . : : : . . .. . : . :. . : .: :. :* . . .: . .: . .. :::..*: * * .. * * ..** : .*.:.* . .* ... * * . . : .. . .. . * .* * .* * * . *.* : :. :: : * :.::*. . * : .. * : . . * .. : : :... . ...:.:.. : .. . .*:****:*:*:: .. .. :**:**** ***.** **** * *****.* * : *:**:***:**:* * :..* . .: : .*:* .: :: * .* ::**", "identical_positions": 283, "similar_positions": 849, "identity": "5.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100426-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C644-1", "uniprot_id": "VIP1_RAT", "id": "P0C644-1", "name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "aln": "---------------------------------------------------------------------------------------------------------------MWSLTANEDEDESATAHFFLGAGD---EGLGTCGIGMRTGESDSEL----------------LEDE-EDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRD--------------------PACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSP-ESSVRKTGSYIYEEFMPTDG-TDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHG-VKASSEGQD--LQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQG--DYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNG-SLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQR---THEDESVNKLHPL----YSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEE-GSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPD------------------------------------------------------------------------------------------RALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPG-----GYRLFSS-SRPPTEMKQSGLG-------SQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAG-LKHRDELLFVPAVKRFS--------VSFAKHPTN------------------------------------------------------------GFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHN------HQASDNPFSPPRTLHSPPLQLRHRSEK------PPWYSSGPSSTVSSAG---------PSSPTTVDGNSHFGFSDQSSVNTQM-----------IEEKQGLGLLQETPGDGTPEFHIE----LAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTC-----------------QPCQAS-QLSKKVYEEICQLCQDN-----PEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRP-----------TQEIPEE---PCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSE---------------------ETDLQAQEVSEEIDQEPEVVDELSNEDIS--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2ARP1-1", "uniprot_id": "VIP1_MOUSE", "id": "A2ARP1-1", "name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "aln": "---------------------------------------------------------------------------------------------------------------MWSLTANED--ESTTAHFFLGAGD---EGLGTCGIGMRTEESDSEL----------------LEDE-EDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRD--------------------PACPEECSLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSP-ESSVRKTGSYIYEEFMPTDG-TDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPEAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHG-VKASNEGQD--LQREPLAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQG--DYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNG-SLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQR---THEDESVNKLHPL----YSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETQDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEE-GSAPAGCGFRPASSENEEMKTDPGSIENLCPGKASDEPD------------------------------------------------------------------------------------------RALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPG-----GYRLFSS-SRPPTEMKQSGLG-------SQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAS-LKHRDELLFVPAVKRFS--------VSFAKHPTN------------------------------------------------------------GFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHN------HQASDSPFSPPRTLHSPPLQLRHRSEK------PPWYSSGPSSTVSSAG---------PSSPTTVDGNSHFGFSDQSSVNIHM-----------TEEKQGFGLLQETPGDGTRELHIERQQELVEPAQSPQELPVEICPSGSQGVTKVSQTCQEVPDIVQPCHNIHEEIGQPQQEVPDISQLLLKDHDTTTNTC-----------------HLCQAS-QLSQKVCEEICQLCQDN-----HEESNQLCQEVSVKLGRMVHGFPVNVDSTAQETLMEIGRP-----------TQEIPED---PYQEFSVKVGVLAQKAPAISELSQDIPEADKPSQELSE---------------------ETELQAQEVSEEIDQESEVVDELPPEAIS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PFW1-1", "uniprot_id": "VIP1_HUMAN", "id": "Q6PFW1-1", "name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "aln": "---------------------------------------------------------------------------------------------------------------MWSLTASEG--ESTTAHFFLGAGD---EGLGTRGIGMRPEESDSEL----------------LEDE-EDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRD--------------------PARPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSP-ESSVRKTGSYIYEEFMPTDG-TDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHG-VKASNEGQD--PQRETLAPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQG--DYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTSLLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNG-SLGLQGTAELLRLSKALADVVIPQEYGISREEKLEIAVGFCLPLLRKILLDLQR---THEDESVNKLHPLCYLRYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETQDAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFHVELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPD------------------------------------------------------------------------------------------RALQTSPQPPEGPGLPRRSPLIRNRKAGSMEVLSETSSSRPG-----GYRLFSS-SRPPTEMKQSGLG-------SQCTGLFSTTVLGGSSSAPNLQDYARSHGKKLPPAS-LKHRDELLFVPAVKRFS--------VSFAKHPTN------------------------------------------------------------GFEGCSMVPTIYPLETLHNALSLRQVSEFLSRVCQRHTDAQAQASAALFDSMHS------SQASDNPFSPPRTLHSPPLQLQQRSEK------PPWYSSGPSSTVSSAG---------PSSPTTVDGNSQFGFSDQPSLNSHV-----------AEEHQGLGLLQETPGSGAQELSIEGEQELFEPNQSPQVPPMET----SQPYEEVSQPCQEVPDISQPCQDISEALSQPCQKVPDISQQCQENHDNGNHTCQE----------VPHISQPCQKSSQLCQKVSEEVCQLCLEN-----SEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETLVEVGSP-----------AEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFPE---------------------EIDLQAQEVPEEIN-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TTL5-1", "uniprot_id": "A0AB32TTL5_DANRE", "id": "A0AB32TTL5-1", "name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase", "aln": "----------------------------------------------------------------------------------------------------------------MSEPSSPGESQRGAPRFFVGCAEDESEGLDDYAS-MR---TDMEL----------------YEDDLEDDSPPERQIVMGICCMMKKSKSKPMTQILERLCKFEYITVVIFPEDVILNEPVEKWPLCDCLISFHSKGFPLDKAVSYAKLRNPLLINDLNMQYYIQDRREVYRILQEEGIDLPRYAVLNRD--------------------PDKPDECNLIEAEDQVEVNGEVFLKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSP-ESSVRKTGSYIYEEFMPTDG-TDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAMEKLVARKVCLAFKQTVCGFDLLRANGHSYVCDVNGFSFVKNSMKYYDDCAKILGNIVMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRNAMFFELFEKYGGYKTGKLKLKKPKQLQEVLDITRTLLADIGQHTDCEIEEKKSKLEQLKTVLEMYGHFSGINRKVQLTYLPHGQPKTSSEEED--TRKE--GPSILLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQG--DYAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDNDIESLSGCQQRVKARLHEIMQKDEVFTEEDYDRLAPTCSSSLVNSMRAVENPVCICDQVYTLVQSLTSQIRKRLEDPKSADLQLYHSETLEMMLQRWSKLERDFRMKSGRYDISKIPDIYDCIKYDVQHNS-SLGLEDTLELFKLSRALADIVIPQEYGINTVEKLDIAYAYCLPLVKKIQLDLQR---THEDESVNKLHPL----YSRGVLSPGRHVRTRLYFTSESHVHSLLSIFRYGGLLDEENDEQWKRAMDYLSAVSELNYMTQIVIMLYEDNNKDPSSEERFHVELHFSPGVKVSEE-ESAPMGFGFRPASAENDQKQTDPGSLENLS----RDEPD------------------------------------------------------------------------------------------RALPLS----EAISTQRKSPLIRNRKTGSMEVLSESSSSKGG-----SYRLFPSCSRQSPEMKQSGLG-------SQCAGLFSTTVLGGSSSAPNLQDYARTHRKKFSSGS-LTYKDELLSMPAVKRFS--------VSFAKHPTNEPLEEHQVAQLLRRFSNDPNIGHPFCLDSAFAHHLHQCSYHLRLFRNWLISGQDPLEYIYGFEGCSMVPSIYPLETLHNSLSLKQVNEFLTTVCENAGDSHTRTTRALSAMFDSQ-----NQPTGESYIPHRVLSSS-VSLRQRSDR------PPWYSSGPSSTVSSAG---------PSSPTTADTSPRFSFSEKITLTPQS-----------SEE----------------------------IHQIPQ--------------NNNCHTVTLTSEPSIPSEDPHSSIPSPIMERP--SQITSDGTDSA---------------------GQCLTE--------SPSCDEGSSP-----NTAEPSPPSPLPESFRGLPGSLPVLLELRESSSETGSSAQ-----------TPLSPEE---PDEFFDT-----QETVDAWRENPASLPHPGTP----------------------------LEVGAPHVPEP-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VR59-1", "uniprot_id": "VIP1_DROME", "id": "Q9VR59-1", "name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase", "aln": "---------------------------------------------------------------------------------------------------------------MSYTELESGYQDISQQHQQQNPHQSQPQQRVGFYLGLQDGNGDTDFGDS----------NDGMDSDTSTSSSNSKQVVVGICAMAKKTQSKPMKEILTRLGEFEFIKLVTFEENVILREPVQNWPTCDCLVSFHSKGFPLEKAIEYAQLRNPFVLNNLHMQYDIQDRRRVYAILEKEGIEIPRYAVLDRD--------------------SPDPKHHELIESEDHVEVNGITFNKPFVEKPVSAEDHNIYIYYPTSAGGGSQRLFRKIGSRSSVYSP-ESRVRKTGSFIYEDFMPTDG-TDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVILNHSEKLISRKVCLAFKQTVCGFDLLRANGKSYVCDVNGFSFVKNSNKYYDDCAKILGNMILRELTPTLHIPWSVPFQLDDPPIVPTTFGKMMELRCVVAVIRHGDRTPKQKMKVEVRHPKFFEIFEKYDGYKLGHVKLKRPKQLQEILDIARFLLSEIHTKAHAEIEEKESKLEQLKNVLEMYGHFSGINRKVQMKYQPKGRPRGSSSDDTNLAADQPVEPSLVLILKWGGELTPAGRIQAEELGRIFRCMYPGGQGRSDYSGTQGLGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANTNGLLDNDCDS-SKYQNLAKGRLHELMQNDREFSKEDRELINPCNSKSITQALDFVKNPVDCCHHVHLLIRELLHIISIKKDDPKTKDAILYHGETWDLMRCRWEKIEKDFSTKSKLFDISKIPDIYDCIKYDLQHNQHTLQYDQAEELYIYAKNLADIVIPQEYGLTPQEKLAIGQGICSPLLRKIKGDLQRNIDEVEDEFMNRLNPH----YSHGVASPQRHVRTRLYFTSESHVHSLLTVLRYGGLLNVVTDEQWRRAMDYISMVSELNYMSQIVIMLYEDPTKDPTSEERFHVELHFSPGVNCCVQ-KNLPPGPGFRPHSHGDNACNVSLQSSDESNPARIEEENDSNSGEEREGKKRGTSGQRSTDRSAERISPAFGFNRLELRSKQFKSKPIPIGAHHTVSGHEAMDLAKRLNEELASHQQQQNQQLRPISPDIRAVTPDCEPRSRSFEQRPTSGVCAKEPDSQVSVSVSASVSSANASTSSRRQRHSIAGQMSYMKMLGFGGFSKKMATSANSLFSTAVISGSSSAPNLRDMITVSSSGFGDVPPIRPLETLHNALSLRKLDSFLQDMILAQIFKTPTGSPPRGFSKNTLPAVSSMTLTASN------------------------------QTEVVEHEPISTTVTPTFDRRGSESGSTADAHLRLLSESQCPNLDDSNTELRESLAGKMELWPQDIVKAAEDEELNLSELETKPSLDLTMEIMERGVAGIASIQPMNRDSDETMGGGVFLSVCEEQGSGSTCLTPVSFGMDLDLSMVANKGSITLSMEGFDDDEDATLSAATTPSLLADCEPRLESCYCCPSHAEAPPEVPSDDPRFGFALPVRVTQASPEHARPVRRAHDPVSPRIQKQISLFEGNAAMATGQEKTESSGSVGGGAILHASINLPAAGPHHLRQDARLRKFENLTQSTSNSNFPFESNTLKRVPMQTTKDYDNVSHTQSCINLKSGSSGVLGGSPQRQRGSDGGGVGASGVPAESREPTRVHYGRMNSTCCSASASPSPSPGALIVKERFIEPPKRGVVRGYHGKTQSMDADFLFNEFLLLPAMAPAKISFDSSDIDQASDDDSPSSSKQRHA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06685-1", "uniprot_id": "VIP1_YEAST", "id": "Q06685-1", "name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase", "aln": "MSGIKKEPIESDEVPQQETKNNLPSAPSEMSPLFLNKNTQKAMQSIAPILEGFSPKTSASENMSLKLPPPGIQDDHSEENLTVHDTLQRTISTALGNGNNTNTVTTSGLKKADSESKSEADPEGLSNSNIVNDADNINSISKTGSPHLPQGTMDAEQTNMGTNSVPTSSASSRKSSTSHPKPRLPKVGKIGVCAMDAKVLSKPMRHILNRLIEHGEFETVIFGDKVILDERIENWPTCDFLISFFSSGFPLDKAIKYVKLRKPFIINDLIMQKILWDRRLCLQVLEAYNVPTPPRLEISRDGGPRANEELRAKLREHGVEVKPVEEPEWKMVDDDTLEVDGKTMTKPFVEKPVDGEDHNIYIYYHSKNGGGGRRLFRKVGNKSSEFDPTLVHPRTEGSYIYEQFMDTDNFEDVKAYTIGENFCHAETRKSPVVDGIVRRNTHGKEVRYITELSDEEKTIAGKVSKAFSQMICGFDLLRVSGKSYVIDVNGFSFVKDNKAYYDSCANILRSTFIEAKK-------KMDMEKKNLPIIREEKEQKWVFKGLAIIIRHADRTPKQKFKHSFTSPIFISLLKGHK----EEVVIRNVNDLKIVLQALRIALDEKAGNP--------AKIKVLANALEKKLNFPGTKIQLKPVLNKEN-----------------EVEKVQFILKWGGEPTHSAKYQATELGEQMRQDFD-----------------LLNKSILQNIKIFSSSERRVLHTAQYWTRALFGADELGS-------DEISIRKDLLDDSNAAKDLMDKVKKKLKPLLREGKEAPP------QFAWPSKMPEPYLVIKRVVELMNYHKKIMDNN-----FAKKDVNSMQTRWCTSEDPSLFKERWDKLFKEFN-NAEKVDPSKISELYDTMKYDALHNR------------QFLENIFDPGLPNEAIADELGSHSLVDRYPINVLAKNNFKIID------SHSMNNSGKN------------SSNSVGSLGWVLESGKTSTARNPKSSSQFDEPR----------FMQLRELYKLAKVLFDFICPKEYGISDAEKLDIGLLTS------------------------------------------------------------------------------------------------------------------------------------------LPLAKQILNDIGDMKNRETPACVAYFTKESHIYTLLNIIYES----------------------------------------GIPMRIARNALPELDYLSQITFELYESTD----------ASGQKSHS-------------------------------------------------------------------------------IRLKMSPGCHTQDPLDVQLDDRHYISCIPKISLTKHLDMDYVQQKLRNKFTR--------VIMPPKFTPVNITSPNLSFQKRKTR------RKSVSVEKLKRPASSG---------SSSSTSVNKTLD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . : . : * : .. . :*:*.* * **** .** ** .. : * : :.*** * :::** *. *:**.*.****:**: * :**:*:::*:* ** : *** :*: .: * :.** . : :* :**:* .: ********..****:**** :. ***.:*****:*.:** :.* *. **:***:** **. ***.**:* ::.***:****.:** *.*::.***:** . *. ** :: **. **.* :*******..*:*:* *********:. ***.**:** . .:. .: : .: **: :: : :***.*******:* .. . *: ::: : .: ::. ::*: :*: * * : .. .*:: * ..** :*.* : ::: .. .: ::****** * .: ** ***. :* : *:.: :::**::*.* ** ** :::.*:. : : .. . . * .* :: . . .* :*: ::::. ...: :. ::. * . :: . .* : : .* .:: **.*: ::* :: * ***.::** :*** ** . : * :*:* . : :: * .: .. :*. : * :. ** * : .. :: : : ** :::::: : . . *::.: * * .: . * :. . . : . . .: . .: *:* . . : . .: * . : . * : .. :.: . . . . : .* .* :: ", "identical_positions": 234, "similar_positions": 293, "identity": "12.48%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100426-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C644-1", "uniprot_id": "VIP1_RAT", "id": "P0C644-1", "name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------MWSLTANEDEDESATAHFFLGAGD-EGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRD--------------------PACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSP-ESSVRKTGSYIYEEFMPTDG-TDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEM--------YGHFSGINRKVQLTYYPHG-VKASSEGQD--LQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQG--DYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNG-SLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQR---THEDESVNKLHPL----YSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETK-DAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEE-GSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPD---------------------RALQTSPQPVEGTGLPRRSPLIRNR--KAGSMEVLS--ETS-SSRPGGYRLFSSS-RPPTEMK------------------------QSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLP-------------PAG-LKHRDELLFVPAVKRFSVSFAKHP---TNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQ---------------RHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHS------------PPLQLRHRSEKPPWYSSGPSSTVSSA--------------------------------------------GPSSPTTVDGNSHFG-------FSDQSSVNTQMIEEKQGLGL-LQETPGDGTPEFHIE----LAESTQSPQEPP------------VEISPPGSQDDTEVN------------QTCQEVPDTIQPCHDILEEIGQPNQEVP---------DISQLLLKNHDTATNTC-------QPCQAS-QLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRP--------------------TQEIPEE---PCQEFSEKVGMLTQKASAISELSQDILETDNPSQELS---------------------EETDLQAQEVSEEIDQEPEVVDELSNEDIS--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2ARP1-1", "uniprot_id": "VIP1_MOUSE", "id": "A2ARP1-1", "name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------MWSLTANED--ESTTAHFFLGAGD-EGLGTCGIGMRTEESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRD--------------------PACPEECSLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSP-ESSVRKTGSYIYEEFMPTDG-TDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPEAEIEEKTGKLEQLKSVLEM--------YGHFSGINRKVQLTYYPHG-VKASNEGQD--LQREPLAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQG--DYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNG-SLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQR---THEDESVNKLHPL----YSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETQ-DAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEE-GSAPAGCGFRPASSENEEMKTDPGSIENLCPGKASDEPD---------------------RALQTSPQPVEGTGLPRRSPLIRNR--KAGSMEVLS--ETS-SSRPGGYRLFSSS-RPPTEMK------------------------QSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLP-------------PAS-LKHRDELLFVPAVKRFSVSFAKHP---TNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQ---------------RHTDAHAQASAALFDSMHNHQASDSPFSPPRTLHS------------PPLQLRHRSEKPPWYSSGPSSTVSSA--------------------------------------------GPSSPTTVDGNSHFG-------FSDQSSVNIHMTEEKQGFGL-LQETPGDGTRELHIERQQELVEPAQSPQELP------------VEICPSGSQGVTKVS------------QTCQEVPDIVQPCHNIHEEIGQPQQEVP---------DISQLLLKDHDTTTNTC-------HLCQAS-QLSQKVCEEICQLCQDNHEESNQLCQEVSVKLGRMVHGFPVNVDSTAQETLMEIGRP--------------------TQEIPED---PYQEFSVKVGVLAQKAPAISELSQDIPEADKPSQELS---------------------EETELQAQEVSEEIDQESEVVDELPPEAIS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PFW1-1", "uniprot_id": "VIP1_HUMAN", "id": "Q6PFW1-1", "name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------MWSLTASEG--ESTTAHFFLGAGD-EGLGTRGIGMRPEESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPSCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLAMQYYIQDRREVYRILQEEGIDLPRYAVLNRD--------------------PARPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSP-ESSVRKTGSYIYEEFMPTDG-TDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVKHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGGEIEEKTGKLEQLKSVLEM--------YGHFSGINRKVQLTYYPHG-VKASNEGQD--PQRETLAPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQG--DYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDGDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTRSTSLLNSMTIIQNPVKVCDQVFALIENLTHQIRERMQDPRSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNG-SLGLQGTAELLRLSKALADVVIPQEYGISREEKLEIAVGFCLPLLRKILLDLQR---THEDESVNKLHPLCYLRYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETQ-DAQWQRALDYLSAISELNYMTQIVIMLYEDNTQDPLSEERFHVELHFSPGVKGVEEEGSAPAGCGFRPASSENEEMKTNQGSMENLCPGKASDEPD---------------------RALQTSPQPPEGPGLPRRSPLIRNR--KAGSMEVLS--ETS-SSRPGGYRLFSSS-RPPTEMK------------------------QSGLGSQCTGLFSTTVLGGSSSAPNLQDYARSHGKKLP-------------PAS-LKHRDELLFVPAVKRFSVSFAKHP---TNGFEGCSMVPTIYPLETLHNALSLRQVSEFLSRVCQ---------------RHTDAQAQASAALFDSMHSSQASDNPFSPPRTLHS------------PPLQLQQRSEKPPWYSSGPSSTVSSA--------------------------------------------GPSSPTTVDGNSQFG-------FSDQPSLNSHVAEEHQGLGL-LQETPGSGAQELSIEGEQELFEPNQSPQVPP------------MET----SQPYEEVS------------QPCQEVPDISQPCQDISEALSQPCQKVP---------DISQQCQENHDNGNHTCQEVPHISQPCQKSSQLCQKVSEEVCQLCLENSEEVSQPCQGVSVEVGKLVHKFHVGVGSLVQETLVEVGSP--------------------AEEIPEEVIQPYQEFSVEVGRLAQETSAINLLSQGIPEIDKPSQEFP---------------------EEIDLQAQEVPEEIN-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PXC2-1", "uniprot_id": "A0A8M9PXC2_DANRE", "id": "A0A8M9PXC2-1", "name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MSKSSGMSNSELPRFLIGSEVGESRKLDNRDMRNISGPYGEEEEEEDEDQSERQIVVGICSMMKKSTSKPMTEILERLCKFEYITVVIFPEEVILGEPVEKWPLCDCLISFHSKGFPLDKAMSYAKLRNPLLINDLNMQYFIQDRREVYRILKEEGIDLPRYAVLNRD--------------------PDRPEECNLVESEDHVEVNGEVFHKPFVEKPVSAEDHNVYIYYPTSAGGGSQRLFRKIGSRSSVYSP-ESTVRKTGSYIYEEFMPTDG-TDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVMLTAMEKLVARKVCLAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKVLGNMVMRELAPQFHIPWSIPMEAEDIPIVPTTSGTMMELRCVIAVIRHGDRTPKQKMKMEVRNALFFELFEKYGGYKSGKLKLKKPKQLQEVLDIARQLLAELVLHNDCEIEEKKSKLEQLKTVLEMESSLNDNQYGHFSGINRKVQLTYLPNGQPKASSEEED--TLKE--GPSLLLVLKWGGELTPAGRVQAEELGRAFRCMYPGGQG--DYAGFPGCGLLRLHSTYRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLTDCQQRVKARLHEIMQKSKDFNDDDYSKLAPTGSPSLVNSMGIIINPVRTCDQVHTLIKSLTQQICRRLEDPKSADLQLYHSESLELMLQRWSKLERDFRMKNGRYDISKIPDIYDCVKYDTQHNS-SLALEDTLELFHLSKALADIIIPQEYGITKAEKLDIASAYCLPLVKKIQLDLQR---THEDEAVNKLHPLWFR-YSRGVMSPGRHVRTRLYFTSESHVHSLLNIFRYGGLLNEQK-DEQWKQAMDYLSAVTELNYMTQIVIMLYEDNNKDPSSEERFHVELHFSPGVKGCKDEENAPLGFGFRPASSENHEKQTNPGSLEDLS----QDEPD---------------------RAVLTEP-----INIQKKSPLVRNR--KGGSMEALS--ESNPSSRGLAYRIFPSSSRQSPEIK------------------------PSGLGAQCAGLFS-------ASFPNLRDLTRAPRKNPS-------------SLKNLSSQAELLSMPAVKRFSVSYARHP---TNGFEGYSLVPSIYPLETLHNSLSLKQVDEFLTALCK---------------NGSETQFKRLKTLSAMFESHSQPSIDVDSLETPVT------------TPVQSQP-TAQSLWYTGGPPSTSS----------------------------------------------GPLSPSVADPSSNFA-------FSSE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VR59-1", "uniprot_id": "VIP1_DROME", "id": "Q9VR59-1", "name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase", "aln": "-------------------------------------------------------------------------------------------------------------------------MSYTELESGYQDISQQHQQQNPHQSQPQQRVGFYLGLQDGNGDTDFGDSNDGMDSDTSTSSSNSKQVVVGICAMAKKTQSKPMKEILTRLGEFEFIKLVTFEENVILREPVQNWPTCDCLVSFHSKGFPLEKAIEYAQLRNPFVLNNLHMQYDIQDRRRVYAILEKEGIEIPRYAVLDRD--------------------SPDPKHHELIESEDHVEVNGITFNKPFVEKPVSAEDHNIYIYYPTSAGGGSQRLFRKIGSRSSVYSP-ESRVRKTGSFIYEDFMPTDG-TDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEIRYPVILNHSEKLISRKVCLAFKQTVCGFDLLRANGKSYVCDVNGFSFVKNSNKYYDDCAKILGNMILRELTPTLHIPWSVPFQLDDPPIVPTTFGKMMELRCVVAVIRHGDRTPKQKMKVEVRHPKFFEIFEKYDGYKLGHVKLKRPKQLQEILDIARFLLSEIHTKAHAEIEEKESKLEQLKNVLEM--------YGHFSGINRKVQMKYQPKGRPRGSSSDDTNLAADQPVEPSLVLILKWGGELTPAGRIQAEELGRIFRCMYPGGQGRSDYSGTQGLGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANTNGLLDNDCDS-SKYQNLAKGRLHELMQNDREFSKEDRELINPCNSKSITQALDFVKNPVDCCHHVHLLIRELLHIISIKKDDPKTKDAILYHGETWDLMRCRWEKIEKDFSTKSKLFDISKIPDIYDCIKYDLQHNQHTLQYDQAEELYIYAKNLADIVIPQEYGLTPQEKLAIGQGICSPLLRKIKGDLQRNIDEVEDEFMNRLNPH----YSHGVASPQRHVRTRLYFTSESHVHSLLTVLRYGGLLNVVT-DEQWRRAMDYISMVSELNYMSQIVIMLYEDPTKDPTSEERFHVELHFSPGVNCCVQ-KNLPPGPGFRPHSHGDNACNVSLQSSDESNPARIEEENDSNSGEEREGKKRGTSGQRSTDRSAERISPAFGFNRLELRSKQFKSKPIPIGAHHTVSGHEAMDLAKRLNEELASHQQQQNQQLRPISPDIRAVTPDCEPRSRSFEQRPTSGVCAKEPDSQVSVSVSASVSSANASTSSRRQRHSIAGQMSYMKMLGFGGFSKKMATSANSLFSTAVISGSSSAPNLRDMITVSSSGFGDVPPIRPLETLHNALSLRKLDSFLQDMILAQIFKTPTGSPPRGFSKNTLPAVSSMTLTASNQTEVVEHEPISTTVTPTFDRRGSESGSTADAHLRLLSESQCPNLDDSNTELRESLAGKMELWPQDIVKAAEDEELNLSELETKPSLDLTMEIMERGVAGIASIQPMNRDSDETMGGGVFLSVCEEQGSGSTCLTPVSFGMDLDLSMVANKGSITLSMEGFDDDEDATLSAATTPSLLADCEPRLESCYCCPSHAEAPPEVPSDDPRFGFALPVRVTQASPEHARPVRRAHDPVSPRIQKQISLFEGNAAMATGQEKTESSGSVGGGAILHASINLPAAGPHHLRQDARLRKFENLTQSTSNSNFPFESNTLKRVPMQTTKDYDNVSHTQSCINLKSGSSGVLGGSPQRQRGSDGGGVGASGVPAESREPTRVHYGRMNSTCCSASASPSPSPGALIVKERFIEPPKRGVVRGYHGKTQSMDADFLFNEFLLLPAMAPAKISFDSSDIDQASDDDSPSSSKQRHA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06685-1", "uniprot_id": "VIP1_YEAST", "id": "Q06685-1", "name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase", "aln": "MSGIKKEPIESDEVPQQETKNNLPSAPSEMSPLFLNKNTQKAMQSIAPILEGFSPKTSASENMSLKLPPPGIQDDHSEENLTVHDTLQRTISTALGNGNNTNTVTTSGLKKADSESKSEADPEGLSNSNIVNDADNINSISKTGSPHLPQGTMDAEQTNMGTNSVPTSSASSRKSSTSHPKPRLPKVGKIGVCAMDAKVLSKPMRHILNRLIEHGEFETVIFGDKVILDERIENWPTCDFLISFFSSGFPLDKAIKYVKLRKPFIINDLIMQKILWDRRLCLQVLEAYNVPTPPRLEISRDGGPRANEELRAKLREHGVEVKPVEEPEWKMVDDDTLEVDGKTMTKPFVEKPVDGEDHNIYIYYHSKNGGGGRRLFRKVGNKSSEFDPTLVHPRTEGSYIYEQFMDTDNFEDVKAYTIGENFCHAETRKSPVVDGIVRRNTHGKEVRYITELSDEEKTIAGKVSKAFSQMICGFDLLRVSGKSYVIDVNGFSFVKDNKAYYDSCANILRSTFIEAKK-------KMDMEKKNLPIIREEKEQKWVFKGLAIIIRHADRTPKQKFKHSFTSPIFISLLKGHK----EEVVIRNVNDLKIVLQALRIALDEKAGNP--------AKIKVLANALEK----------KLNFPGTKIQLKPVLNK---------------ENEVEKVQFILKWGGEPTHSAKYQATELGEQMRQDFD-----------------LLNKSILQNIKIFSSSERRVLHTAQYWTRALFGADELGS-------DEISIRKDLLDDSNAAKDLMDKVKKKLKPLLREGKEAPP------QFAWPSKMPEPYLVIKRVVELMNYHKKIMDNN-----FAKKDVNSMQTRWCTSEDPSLFKERWDKLFKEFN-NAEKVDPSKISELYDTMKYDALHNR------------QFLENIFDPGLPNEAIADELGSHSLVDRYPINVLAKNNFKIID-----------------------------SHSMNNSGKNSSNSVGSLGWVLESGKTSTARNPKSSSQFDEPRFMQLRELYKLAKVLFDFICPKEYGISDAEKLDIGLLTS---------------------------------------------------------------------------------------LPLAKQILNDIGDMKNRE--------TPACVAYFTKESHIYTLLN---------------------------------------------IIYESGIPMRIARNALP--------------------ELDYLSQITFELYESTDASGQ---KSHSIRLKMSPGCHTQDPLDVQLDDRHYISCIPKISLT----------------KHLDMDYVQQKLRNKFTRVIMPPKFTPVNITSP-------------NLSFQKRKTRRKSVSVEKLKRPASS--------------------------------------------GSSSSTSVNKTLD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .: . .. . . :*:*:* * **** .** ** .. : * : :.*** * :::** *. *:**.*.****:**: * :**:*:::*:* ** : *** :*: .: * :.** : : .:* :**:* .: ********..****:**** :. ***.:*****:*.:** :.* *. **:***:** **. ***.**:* ::.***:****.:** *.*::.***:** . *. ** :: **. **.* :*******..*:*:* *********:. ***.**::* . .:. .: : .: **: :: : :***.*******:* .. . *: ::: : .: ::. ::*: :*: * * * . .*:: * ..** ::. . *:*:. : : .: ::****** * .: ** ***. :* : *:.: :::**::*.* ** ** :::.*:. : : .. . . * .* :: .. . .* :*: ::::. . .: :. .: . * . :: . .* : : .* .*: **.*: ::* : * ***.::** :*** ** : : * :*:* . : :: * .: * .. .*.. * ** ::. * . . : : : ** :::::: : . . *::.: * * :. * . . . . : :. : * : . : * :. . : . . * . :.*. *. :: . : : . . . . : . : .. .. : ", "identical_positions": 234, "similar_positions": 291, "identity": "12.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100426-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZRH3-1", "uniprot_id": "A0A8I5ZRH3_RAT", "id": "A0A8I5ZRH3-1", "name": "10-formyltetrahydrofolate dehydrogenase", "aln": "MLWRGSQALRHFSTGRVYFKNKLKLALIGQSLFGQEVYSHLL-KEGHRVVGVFTVPDKDGKADPLALAAEKDGTPVFKFPRWRVKGKTIKEVAEAYQSVGAELNVLPFCTQFIPMDIIDSPEHGSIIYHPSLLPRHRGASAINWTLIMGDKKAGFSVFWADDGLDTGPILLQRSCDVKPNDTVDSLYNRFLFPEGIKAMVEAVQLIADGKAPRTPQPEEGATYEG-IQKKENAEIPWDQPAEVLHNWIRGHDKVPGAWAEIDG-----QMVTFYGSSLLTS-SVPAGEPLDIRGAKKPGLVTKNGLVLFGNDGKALMVRNLQFEDGKMIPASQYFSSGE-TSVVELTAEELKVAETIKVIWARILSNVPVIEDSTDFFKSGASSMDVARLVEEIRQKCGGLQLQNEDVYMARKFGDFIQKVVRRLRGEDQ---EAELVVDYVSKEVNEMTVKMPYQCFINGQFVDAEDGETYATINPTDGTTLCRVSYASLADVDRAVAAAKDAFENGEWGRMNARDRGRLMYRLADLMEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKI-QGSTIPINQARPNYNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELTVKAGFPKGVINIIPGSGGVAGQRLSQHPDIRKLGFTGSTSVGKQIMKSCAVSNLKKVSLELGGKSPLIIFSDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEEAIHDEFVTRVVEEIK-KMKIG---DPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGATLVYGGRQVQ---RPGFFMEPTVFTGVEDHMYLAKEESFGPIMVISKFQNGDIDGVLQRANNTEYGLASGVFTRDISKAMYVSDRLEAGTVFINTYNKTDVAAPFGGVKQSGFGKDLGEEALNEYLKTKTVTLEY----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K009-1", "uniprot_id": "AL1L2_MOUSE", "id": "Q8K009-1", "name": "Mitochondrial 10-formyltetrahydrofolate dehydrogenase", "aln": "MLWRGSQALRHFSTSRVYFKNKLKLALIGQSLFGQEVYSQLL-KEGHRVVGVFTVPDKDGKADPLALAAEKDGTPVFKFPRWRLKGKTIKEVAEAYQSVGAELNVLPFCTQFIPMDVIDSPKHGSIIYHPSLLPRHRGASAINWTLIMGDKKAGFSVFWADDGLDTGPILLQRSCDVKPNDTVDSLYNRFLFPEGIKAMVEAVQLIADGKAPRTPQPEEGATYEG-IQKKENAEVSWDQPAEGLHNWIRGHDKVPGAWAEING-----QMVTFYGSSLLTS-SVPSGEPLDIRGAKKPGLVTKNGLVLFGNDGKALMVRNLQFEDGKMIPASQYFSAGE-TSVVELTAEELKVAETIKVIWARILSNTPVIEDSTDFFKSGASSMDVVRLVEEIRQSCGGLQLQNEDVYMATKFGDFIQKVVRRLRGEDE---EAEMVVDYVSKEVNGMTVKIPYQCFINGQFVDAEDGETYATVNPTDGTTICRVSYASLADVDRAVAAAKDAFENGEWGRMNARDRGRLMYRLADLMEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKI-QGSTIPINQARPNYNLTFTKKEPLGACAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELTVKAGFPKGVINIIPGSGGVAGQRLSQHPDIRKLGFTGSTSVGKQIMKSCAVSNLKKVSLELGGKSPLIIFSDCDLEKAVRMGMGAVFFNKGENCIAAGRLFVEEAIHDEFVTRVVEEIK-KMKIG---DPLDRSTDHGPQNHRAHLEKLLQYCETGVQEGATLVYGGRQVQ---RPGFFMEPTVFTGVEDHMYLAKEESFGPIMVISKFQNGDIDGVLQRANNTEYGLASGVFTRDINKAMYVSDKLEAGTVFINTYNKTDVAAPFGGMKQSGFGKDLGEEALNEYLKIKTVTLEY----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3SY69-1", "uniprot_id": "AL1L2_HUMAN", "id": "Q3SY69-1", "name": "Mitochondrial 10-formyltetrahydrofolate dehydrogenase", "aln": "MLRRGSQALRRFSTGRVYFKNKLKLALIGQSLFGQEVYSHLR-KEGHRVVGVFTVPDKDGKADPLALAAEKDGTPVFKLPKWRVKGKTIKEVAEAYRSVGAELNVLPFCTQFIPMDIIDSPKHGSIIYHPSILPRHRGASAINWTLIMGDKKAGFSVFWADDGLDTGPILLQRSCDVEPNDTVDALYNRFLFPEGIKAMVEAVQLIADGKAPRIPQPEEGATYEG-IQKKENAEISWDQSAEVLHNWIRGHDKVPGAWTEING-----QMVTFYGSTLLNS-SVPPGEPLEIKGAKKPGLVTKNGLVLFGNDGKALTVRNLQFEDGKMIPASQYFSTGE-TSVVELTAEEVKVAETIKVIWAGILSNVPIIEDSTDFFKSGASSMDVARLVEEIRQKCGGLQLQNEDVYMATKFEGFIQKVVRKLRGEDQ---EVELVVDYISKEVNEIMVKMPYQCFINGQFTDADDGKTYDTINPTDGSTICKVSYASLADVDKAVAAAKDAFENGEWGRMNARERGRLMYRLADLLEENQEELATIEALDSGAVYTLALKTHIGMSVQTFRYFAGWCDKI-QGSTIPINQARPNRNLTFTKKEPLGVCAIIIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELSVKAGFPKGVINIIPGSGGIAGQRLSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFNDCELDKAVRMGMGAVFFNKGENCIAAGRLFVEESIHDEFVTRVVEEIK-KMKIG---DPLDRSTDHGPQNHKAHLEKLLQYCETGVKEGATLVYGGRQVQ---RPGFFMEPTVFTDVEDYMYLAKEESFGPIMVISKFQNGDIDGVLQRANSTEYGLASGVFTRDINKAMYVSEKLEAGTVFINTYNKTDVAAPFGGVKQSGFGKDLGEEALNEYLKTKTVTLEY----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RK21-1", "uniprot_id": "A0A8M1RK21_DANRE", "id": "A0A8M1RK21-1", "name": "10-formyltetrahydrofolate dehydrogenase", "aln": "MLWTANTIMRKFSSSSVYYQNKLKLALIGQSLFGQEVYTNLR-KQGHKVVGVFTVPDKDGKADPLAVVAEKDGTPVFKFPRWRVKGKPIPEVVEAYKAVGAELNVMPFCSQFIPMNVIDFPKHGSIIYHPSILPKHRGASAINWTLIEGDKKAGFSVFWADDGLDTGPILLQKECQVEPNDTVDTLYNRFLFPEGIKAMVEAVQLIANGKAPKIPQSEEGASYEG-IQKKSNAKVNMAQPAEAIHNWIRGHDKVPGAWVVMDG-----KPVTVYGSSVLSG-SVPAGQPIDIEGASQPGLITKSGLLLFGSDGKALQVKSLQFEDGKMIPASKYFSSEE-SASLDLTDDEKKMAEEIRAIWKGILSNVAAIEETTDFFKCGAASMDVVRLVEEVKQKCAGVQLQNEDVYMATTFQSFIQMLVRRLRGEDQ---EEEMLIDYATKEVNNMTVKMPYQCFINGKFEDADDGKTYNTVNPTDGSVICKVSYASVADVDKAVSAAKEAFDNGPWGKMNPRDRGQLLYRLADLMEEHQEELATIETIDSGAVYTLALKTHVGMSIQTFRYFAGWCDKI-QGSTIPINQARPNRNLTFTKKEPLGVCAIVIPWNYPLMMLAWKSAACLAAGNTLVLKPAQVTPLTALKFAELTIKAGIPKGVINIVPGSGGLVGQRMSEHPDIRKLGFTGSTPIGKQIMKSCAVSNLKKVSLELGGKSPLIIFSDCDMDKAVRMGMSSVYFNKGENCIAAGRLFVEESIHDEYIRRVVEEIK-KMKIG---DPLDRSTDHGPQNHKAHMDKLVEYCEIGVKEGATLVYGGRQVD---RPGFFMEPTVFTDVEDHMFIAKEESFGPVMVVSKFKDGDVDGVLSRANDTEFGLASGVFTRDINKAMYVSERLEAGTVFINTYNKTDVAAPFGGFKQSGFGKDLGEDALHEYLRTKAVTVEY----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIC9-1", "uniprot_id": "Q9VIC9_DROME", "id": "Q9VIC9-1", "name": "10-formyltetrahydrofolate dehydrogenase", "aln": "------------------MALKMRIAIIGQSNFAADVLELLLDRSNIQIVGVFTIPDKGSREDILATTATIHNIPVFKFACWRRKGVALPEVLEQYKSVGATLNVLPFCSQFIPMEVINGALLGSICYHPSILPRHRGASAISWTLIEGDEVAGFSIFWADDGLDTGPLLLTRQTNVESTDTLDTIYKRFLYPEGVKAMGVAVDMVASGTAPKIIQPEVGATYDPAMFKTENQVINLQATAEKIWNFVRGLDSVPGAIATVLHGNGTEEQIRLFGAHLYSAGPVSNGKVLRLRGLTKTAWIHSGGLLIEGTDGAFVNIRRIKRG-TKVISASEWFKQAEDQSITDFSEDELVKRSLLAGIWKAILK--EDVESSTDFFASGAGSMDVVRLVEEVKEAFD-VPLQNEQVFMAPVFEEFFSLLVRFLRQGSAGFGNQQLDFEAFTLKANKREIRVPTQLFINGEFVDAEAQRTLEIVNPTNEEVLCKVACASATDVDKAVRAAHSAFY-GSWRQITPRQRGQLMLNLADLMERNKEELATIESVDSGAVYTLALKTHVGMSIEAWRYFAGWCDKI-QGNTIPVNPARPNNVLTFTRKEPIGVCGLITPWNYPLMMLSWKMAACIAAGNTCLIKPAQTCPLTALKFAELTVRAGFPPGVINVLPGKGSDAGQAVADHELVRKLGFTGSTPIGKHIMKSCADSNLKKCSLELGGKSPLIIFADCDMDKAVKHGMSSVFFNKGENCIAAGRLFVEDRIHDEFIRRVLKDLR-TMTIG---DPLDRSTAHGPQNHKAHFDKLLEFCRRGVDEGAKLVYGGCRVPN--LKGYFFTPTVFTNVTDDMFIAQEESFGPIMIISKFNGSDIDSLMQRANRTEYGLASGVFTKDIGKALNFADRIEAGTVFVNVYNKTDVAAPFGGFKQSGYGKDLGQEALNEYLKTKCVTVEY----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P54114-1", "uniprot_id": "ALDH3_YEAST", "id": "P54114-1", "name": "Aldehyde dehydrogenase [NAD(P)+] 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPTLYTDIEIPQLKISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAFD-NVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPFHSNAKQDLAQIIELTRYYAGAVDKFNMGETIPLTFN----KFAYTLKVPFGVVAQIVPWNYPLAMACRKMQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVVNVIPGYGSVVGKALGTHMDIDKISFTGSTKVGGSVLEASGQSNLKDITLECGGKSPALVFEDADLDKAIEWVANGIFFNSGQICTANSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKKEEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPETSKLLRDEIFGPVVVVSKFTN--YDDALKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINQTNQEEAKVPFGGFKMSGIGRESGDTGVDNYLQIKSVHVDLSLDK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P47771-1", "uniprot_id": "ALDH2_YEAST", "id": "P47771-1", "name": "Aldehyde dehydrogenase [NAD(P)+] 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPTLYTDIEIPQLKISLKQPLGLFINNEFCPSSDGKTIETVNPATGEPITSFQAANEKDVDKAVKAARAAFD-NVWSKTSSEQRGIYLSNLLKLIEEEQDTLAALETLDAGKPYHSNAKGDLAQILQLTRYFAGSADKFDKGATIPLTFN----KFAYTLKVPFGVVAQIVPWNYPLAMACWKLQGALAAGNTVIIKPAENTSLSLLYFATLIKKAGFPPGVVNIVPGYGSLVGQALASHMDIDKISFTGSTKVGGFVLEASGQSNLKDVTLECGGKSPALVFEDADLDKAIDWIAAGIFYNSGQNCTANSRVYVQSSIYDKFVEKFKETAKKEWDVAGKFDPFDEKCIVGPVISSTQYDRIKSYIERGKREEKLDMFQTSEFPIGGAKGYFIPPTIFTDVPQTSKLLQDEIFGPVVVVSKFTN--YDDALKLANDTCYGLASAVFTKDVKKAHMFARDIKAGTVWINSSNDEDVTVPFGGFKMSGIGRELGQSGVDTYLQTKAVHINLSLDN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * ***.:* :. .* :**: : . *. ***:** **: ** . * : ...:** : .* .*:*..:: **::*::*:* : * .:. :: **:** **: * ***:. :::* * *:*. . : ****** * . * ..:***** ::***: .*: * ** * :**:* **:*::** *. .*: :. * : *:.***** :* ::::.. ****. :** ***** ::* *.:::**: .:::*.*: * * .*::*:. *:*::: :. : : :. **:*.. ** :: ::: .: . * * :: .. *:*: **:**.* : : ::* ***::::*** . *. :. ** * :****.***:*: ** .: ::****::* *. :. .****.* ** *:: *: .:. **: * * :: ", "identical_positions": 160, "similar_positions": 164, "identity": "16.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100427-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M6B3-1", "uniprot_id": "F1M6B3_RAT", "id": "F1M6B3-1", "name": "", "aln": "MALRGEHASGPGVSSSSVDCSRITVSRELLTAGSEGSRGVWDQLLINSKPHSRKASTLQTVRVQRSPLLDQVQAFLPQMAQANEKLRKEMAVAPAGHFNIENIDETSGNIIQMDVALFEMNQSEDSKEDDNPEESSQDSSGDSSESED-DDCIPSEVTIENIKLPNTEGGKGKIQVLDSPASKKKKQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CX66-1", "uniprot_id": "NOPC1_MOUSE", "id": "Q9CX66-1", "name": "NOP protein chaperone 1", "aln": "MEFQGERGTGPGVSSSSVACSQVTVSRELLTAGSEGSGGIWDQLLISSKPHPRKTSTLQTVRMQRSPLLDQVQAFLPQMAQANEKLRREMAAAPAGHFNIENIDETSGNIIQMDVALFEMSRS-DSKEEDSPEESSRDSSGDSSESEE-DVCVPSEVTIENIKLPNAEGGKGKIEILDSPASKKKKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N5I9-1", "uniprot_id": "NOPC1_HUMAN", "id": "Q8N5I9-1", "name": "NOP protein chaperone 1", "aln": "MEVHGKPKASPSCSSPTRDSSGVPVSKELLTAGSDGRGGIWDRLLINSQPKSRKTSTLQTVRIERSPLLDQVQTFLPQMARANEKLRKEMAAAPPGRFNIENIDGPHSKVIQMDVALFEMNQS-DSKEVDSSEESSQDSSENSSESEDEDDSIPSEVTIDNIKLPNSEGGKGKIEVLDSPASKKKK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P1M8-1", "uniprot_id": "A0A8M1P1M8_DANRE", "id": "A0A8M1P1M8-1", "name": "", "aln": "------------MAQTQYCTKKATSSKDLLTCGN--GKGIHEKLLLNS-----KGASLKTERVSRSNVLDRLQNFLPQMAQANESLRQQMQEAPAGFFNIETVED-AEKVIEMDVALVELEES-DSSEVD--EESSSSSEEDSSEEEL------QTVTAKTLKLPGDRKRKANIQMLEKEAE-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. . . *::***.*. *: ::**:.* * ::*:* *:.** :**::* ******:***.**::* **.* ****.:: ::*:*****.*:..* **.* * **** .*. :***.* . ** ..:***. . *.:*::*:. *. ", "identical_positions": 67, "similar_positions": 55, "identity": "35.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100427-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0KXK2-1", "uniprot_id": "A0ABK0KXK2_RAT", "id": "A0ABK0KXK2-1", "name": "Solute carrier family 41 member", "aln": "-------------------------MTHSKGRPATYKTSASPESGGGFVDWTLNLNTIQSDKFLNLLLSMVPVIYQKNQ--EDRHKKVNGIWQDGLSGAAQT--FSKRSEPHLDYHEFSEQAFHSGG-GHTPASCSP--------------------RYDDYAGYNYCDGREASETTAMLQDEDPSS---------------------------------------------------------------------QGD-DVIVETSQRLPKESSGVMALQILVPFLLAGFGTVSAGMVLDIVQHWEVFKNVTEVFILVPALLGLKGNLEMTLASRLSTAVNVGKMDSPIEKWNLIIGNLALKQVQATVVGFLAAVAAIILGWIPEGKYYLSHSILLCSSSVATAFIASLLQGIIMVGVIVGSKKTGINPDNVATPIAASFGDLITLAILAWISQGLYSCLETYYYISPLVCAFFLALTPIWIIIAAKHPATRTVLHSGWEPVITAMVISSIGGLILDTTVSDPNLVGIVVYTPVINGIGGNLVAIQASRISTYLHLHSLPGELPEEPKGCSYPFRTFFGSGVNNKSAQVLLLFVIPGHLIFLYTIHLMKSGHTSLTVVFVVVYLLAAVLQVFTLLWIADWMVHRFWRKGKDPDSFSIPYLTALGDLLGTALLALSFHFLWLIGDRDGDVGD------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BYR8-1", "uniprot_id": "S41A2_MOUSE", "id": "Q8BYR8-1", "name": "Solute carrier family 41 member 2", "aln": "-------------------------MTHSKGRPVTYKTSASPESGGGFVDWTLNLNTIQSDKFLNLLLSMVPVIYQKNQ--EDRHKKVNGIWQDGLSGAAQT--FSKRSEPHLDYHEFSEQAFHSSSSGHTPASCSP--------------------KYDDYAGYNYCDGREASETTAMLQDEDLSS---------------------------------------------------------------------EGD-DVIVETSQRIPKESSGVMALQILVPFLLAGFGTVSAGMVLDIVQHWEVFKNVTEVFILVPALLGLKGNLEMTLASRLSTAVNVGKMDSPIEKWNLIIGNLALKQVQATVVGFLAAVAAIILGWIPEGKYYLSHSILLCSSSVATAFIASLLQGIIMVGVIVGSKKTGINPDNVATPIAASFGDLITLAILAWISQGLYSCLETYYYISPLVCAFFLALTPIWIIIAAKHPATRTVLHSGWEPVITAMVISSIGGLILDTTVSDPNLVGIVVYTPVINGIGGNLVAIQASRISTYLHLHSIPGELPEEPKGCSYPFRTFFGSGVNNKSAQVLLLFVIPGHLIFLYTIHLMKSGHTSLTVVFVVVYLFAAVLQVFTLLWIADWMVHRFWRKGKDPDSFSIPYLTALGDLLGTALLALSFHFLWLIGDRDGDVGD------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JW4-1", "uniprot_id": "S41A2_HUMAN", "id": "Q96JW4-1", "name": "Solute carrier family 41 member 2", "aln": "-------------------------MTNSKGRSITDKTSGGPSSGGGFVDWTLRLNTIQSDKFLNLLLSMVPVIYQKNQ--EDRHKKANGIWQDGLSTAVQT--FSNRSEQHMEYHSFSEQSFHANN-GHASSSCSQ--------------------KYDDYANYNYCDGRETSETTAMLQDEDISS---------------------------------------------------------------------DGDEDAIVEVTPKLPKESSGIMALQILVPFLLAGFGTVSAGMVLDIVQHWEVFRKVTEVFILVPALLGLKGNLEMTLASRLSTAVNIGKMDSPIEKWNLIIGNLALKQVQATVVGFLAAVAAIILGWIPEGKYYLDHSILLCSSSVATAFIASLLQGIIMVGVIVGSKKTGINPDNVATPIAASFGDLITLAILAWISQGLYSCLETYYYISPLVGVFFLALTPIWIIIAAKHPATRTVLHSGWEPVITAMVISSIGGLILDTTVSDPNLVGIVVYTPVINGIGGNLVAIQASRISTYLHLHSIPGELPDEPKGCYYPFRTFFGPGVNNKSAQVLLLLVIPGHLIFLYTIHLMKSGHTSLTIIFIVVYLFGAVLQVFTLLWIADWMVHHFWRKGKDPDSFSIPYLTALGDLLGTALLALSFHFLWLIGDRDGDVGD------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F597-1", "uniprot_id": "E7F597_DANRE", "id": "E7F597-1", "name": "Solute carrier family 41 member", "aln": "------------------------MSLRTIGGAVLSSLGPSLAAQAGGAWSSVSFRPIP-----CMLQTMVPSGYTALQ--EERLAMVD-LGTPKPESHKNG--FHRESRRHSDRGSRTSISLSEAG-DGRYAETEP--------------------MLPESR----LSGEEADE-------EEEES---------------------------------------------------------------------EEEKQQLRNVN--MPKESLLAMGLQILVPFLLAGFGTVSAGVVLDIVQHWEAFKTVTEIFILVPALLGLKGNLEMTLASRLSTAVNVGKMDSPIEKWNLIIGNLALKQVQATVIGFLAAVAAVVLGWIPEGKFQISHAVLLCSSSVATAFIASLLQGIIMVGVIVGSKKTGINPDNVATPIAASFGDLITLAILAWISQGLYNCIDSHPYVSFLVCAFFISLTPLWMVISSKHPASRQLLYSGWEPVITAMFISSIGGLILDKTVSDPNLAGMVVYTPVINGIGGNLVAIQSSRISTYLHFHSTPGEVPDEAKGCYYPCRTFCGSGANHRSAQVLLLLVIPGQLIFLYTIDLMERGHTSLTVVFILVYLAAALFQVFLLLCIADWMVHSMWKSGKDPDSFSIPYLTALGDLLGTALLALSFHFLWTIGDQDSDVGD------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JV32-1", "uniprot_id": "A8JV32_DROME", "id": "A8JV32-1", "name": "SLC41A/MgtE integral membrane domain-containing protein", "aln": "MSCICEYSLERSQINAKMSLPNEQTNLPHNPSQPASADTQTPATATGTTTPSTPTPSTRTTQPNELKHRLTPLNVRRLSGYVNPQAISDNAGDDPPPTTINIGLFNNNNNNNTNNNNNNNNNNNNTASTTPPSAYATPPIYQQQLSTLTATTPLDVAPDDKYRLFTIFNGNDPDNEKLSGLPHSTTGSLSSIITTSIASSEPDPGAVSGGGGGGGGGGGGGGIGGAGGGGGGGGGNGGIGSGALVAADASSIAGINGSSEEKLALNRPGIKQEKWTTILLQVSIPFFLAGIGTIGAGIVLGRVEKWYVFKNVSELFILVPALLGLKGNLDMCLASRLSTQVNLGNMTSRQGVIRMIVGNIALVQVQATVASFLVAMFAVSVGAAMTGDFYFENMMLLTASAMFTATSSCFVLDFVLVAVILFSQKYRLNPDNLATPLAASIGDVVSISLLSFIASLLYDHIKTHLWITFIVVTCYLVLLPMWVMIVLRNEYTRPVLKSGWVPVLSALCISGLGGLVLDAAVEVFN--GFVVFQPIINGIGGNLVSVQASKISTMLHQSSIIGIIPPHTQIFEWPWRALFKGVPYAKTARILIAMSIPGNVLFIFAADYINYSTSTVTWVFVLSYLTASLVQVMLLLYIAHIIVHAMWKWKIDPDNSAIPYLTALGDLLGSSLLAVAWLFTMSVGMQYGSGMETLNAPN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . : . : :.* . : : : * .... : : . .. : . .*.:..: .. . . : : : :*. : **: :**:***:**:.**:**. *::* .*:.*:*:**************:* ******* **:*:* * .:*:**:** ****** .**.*: *: :* *.: :.: :** :*:: ** :.:: .:::*.**: *:* :****:***:***:**::::::*::*:. **. :.:: ::: :* . :: * *:*::* :: :* :* *** **::*: **.:***:** :*. * *:**: *:*********::*:*:*** ** * * :* ..: :* *:: ::*::*: : ***:::*::: . :: . :::* :*:: ** .::.**: ** **. :** :*: ***. :************::***::: * :* : .. : ", "identical_positions": 179, "similar_positions": 183, "identity": "25.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100427-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZG3-1", "uniprot_id": "D3ZZG3_RAT", "id": "D3ZZG3-1", "name": "", "aln": "MPGGVPWSVYLKMLSSSLLAMCAGAQVVHWYYRPDLTIPEIPPKPGELRTELLGLRERHRESQVSQQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BTC1-1", "uniprot_id": "UQCC6_MOUSE", "id": "Q8BTC1-1", "name": "Ubiquinol-cytochrome c reductase complex assembly factor 6", "aln": "MPGGVPWSAYLKMLSSSLLAMCAGAQVVHWYYRPDLTIPEIPPKPGELKTELLGLKERRHEPHVSQQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q69YU5-1", "uniprot_id": "UQCC6_HUMAN", "id": "Q69YU5-1", "name": "Ubiquinol-cytochrome c reductase complex assembly factor 6", "aln": "MPAGVPMSTYLKMFAASLLAMCAGAEVVHRYYRPDLTIPEIPPKRGELKTELLGLKERKHKPQVSQQEELK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXZ6-1", "uniprot_id": "UQCC6_DANRE", "id": "E7EXZ6-1", "name": "Ubiquinol-cytochrome-c reductase complex assembly factor 6", "aln": "MPAGVSWPRYLRMFAASVLSMFAGAQVVHHYYRPDLSIPEIPPKPGELRTELLGLKERQMDSQKQ------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z0X7-1", "uniprot_id": "UQCC6_DROME", "id": "B7Z0X7-1", "name": "Ubiquinol-cytochrome c reductase complex assembly factor 6", "aln": "MPAGVSWGQYLKFLGCALASMMAGSQAVHLYYKPLEDLRVYIEQ--EQHSTQVDPTAKPPESA--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.**. **:::..:: :* **::.** **:* : : * :: :. : .. ", "identical_positions": 15, "similar_positions": 23, "identity": "21.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100427-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2M389-1", "uniprot_id": "WASC4_HUMAN", "id": "Q2M389-1", "name": "WASH complex subunit 4", "aln": "MAVETLSPDWEFDRVDDGSQKIHAEVQLKNYGKFLEEYTSQLRRIEDALDDSIGDVWDFNLDPIALKLLPYEQSSLLELIKTENKVLNKVITVYAALCCEIKKLKYEAETKFYNGLLFYGEGATDASMVEGDCQIQMGRFISFLQELSCFVTRCYEVVMNVVHQLAALYISNKIAPKIIETTGVHFQTMYEHLGELLTVLLTLDEIIDNHITLKDHWTMYKRLLKSVHHNPSKFGIQEEKLKPFEKFLLKLEGQLLDGMIFQACIEQQFDSLNGGVSVSKNSTFAEEFAHSIRSIFANVEAKLGEPSEIDQRDKYVGICGLFVLHFQIFRTIDKKFYKSLLDICKKVPAITLTANIIWFPDNFLIQKIPAAAKLLDRKSLQAIKIHRDTFLQQKAQSLTKDVQSYYVFVSSWMMKMESILSKEQRMDKFAEDLTNRCNVFIQGFLYAYSISTIIKTTMNLYMSMQKPMTKTSVKALCRLVELLKAIEHMFYRRSMVVADSVSHITQHLQHQALHSISVAKKRVISDKKYSEQRLDVLSALVLAENTLNGPSTKQRRLIVSLALSVGTQMKTFKDEELFPLQVVMKKLDLISELRERVQTQCDCCFLYWHRAVFPIYLDDVYENAVDAARLHYMFSALRDCVPAMMHARHLESYEILLDCYDKEIMEILNEHLLDKLCKEIEKDLRLSVHTHLKLDDRNPFKVGMKDLALFFSLNPIRFFNRFIDIRAYVTHYLDKTFYNLTTVALHDWATYSEMRNLATQRYGLVMTEAHLPSQTLEQGLDVLEIMRNIHIFVSRYLYNLNNQIFIERTSNNKHLNTINIRHIANSIRTHGTGIMNTTVNFTYQFLKKKFYIFSQFMYDEHIKSRLIKDIRFFREIKDQNDHKYPFDRAEKFNRGIRKLGVTPEGQSYLDQFRQLISQIGNAMGYVRMIRSGGLHCSSNAIRFVPDLEDIVNFEELVKEEGLAEETLKAARHLDSVLSDHTRNSAEGTEYFKMLVDVFAPEFRRPKNIHLRNFYIIVPPLTLNFVEHSISCKEKLNKKNKIGAAFTDDGFAMGVAYILKLLDQYREFDSLHWFQSVREKYLKEIRAVAKQQNVQSASQDEKLLQTMNLTQKRLDVYLQEFELLYFSLSSARIFFRADKTAAEENQEKKEKEEETKTSNGDLSDSTVSADPVVK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UMB9-1", "uniprot_id": "WASC4_MOUSE", "id": "Q3UMB9-1", "name": "WASH complex subunit 4", "aln": "MAVDTLSPDWDFDRVDDGSQKIHAEVQLKNYGRFLEEYTSQLRRIEDALDDLIGDVWDFNLDPIALKLLPYEQSSLLELIKTENKVLNKVITVYAALCCEIKKLKYEAETKFYNGLLFYGEGATDSSMVEGDCQIQMGRFVSFLQELSCFVTRCYEVVMNVIHQLAALYISNKIGPKIIETTGVHFQTMYEHLGELLTVLLTLDEIVDNHVTLKDHWTMYKRLLKSVHHNPSKFGIQEEKLKPFEKFLLKLEGQLLDGMIFQACIEQQFDSLNGGISVSKNSTFAEEFAHSIRSIFANVEAKLGEPSEIDQRDKYVGICGLFVLHFQIFRTVDKKFYKSLLDICKKVPAITLTANIIWFPDNFLIHKMPAAAKLLDRKSLQAIKIHRDTFLQQKAQSLNKDVQSYYVFVSSWMMKMESMLSKEQRMDTFAEDLTNRCNVFIQGFLYAYSISTIIKTTMNLYMSMQKPMTKTSVKALCRLIELLKAIEHMFYRRSMVVADSVSHITQHLQHQALSSISVAKKRVISDKKYSEQRLDVLSALVLAENTLNGPSTKQRRLIVSLALSVGTQMKTFKDEELFPLQVVMKKLDLISELRERVQAQCDCCFLYWHRAVFPIYLDDVYENAVDAARLHYMFSALRDCVPAMMHSRHLESHELLLDCYDKEIMDILNEHLLDKLCKEIEKDLRLSVHTHLKLDDRNPFKVGRKDLALFFSLNPIRFFNRFIDIRAYVTHYLDKTFYNLTTVALHDWATYSEMRNLATQRYGLVMTEAHLPSQTLEQGLDVLEIMRNIHIFVSRYLYNLNNQIFIERTSNNKHLNTINIRHIANSIRTHGTGIMNTTVNFTYQFLKKKFYIFSQFMYDEHIKSRLIKDIRFFREIKDQNDHKYPFDRAEKFNRGIRKLGITPEGQSYLDQFRQLISQIGNAMGYIRMIRSGGLHCSSNAIRFVPDLEDIVSFEELVKEEGLAEETLRAARHLDSVLSDHTRNSAEGTEYFKMLVDVFAPEFRRPKNIHLRNFYIIVPPLTLNFVEHSISCKEKLNKKNKLGAAFTDDGFAMGVAYTLKLLDQYQEFDSLHWFQSVREKYIKEIRAVAKQQNVQSTSQDEKLLQTMNLTQKRLEVYLQEFELLYFSLSSARIFFRADKTAAEENQEKKEKEEETKTSNGDGPESTVSADPVVK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F4L4-1", "uniprot_id": "E7F4L4_DANRE", "id": "E7F4L4-1", "name": "", "aln": "MAVDSLSPDWEFDRFDDGSQKIHTEVQVKNYERFLEEYIAQLQGIEEALDDSIGDVWDFTLDPITLKLLPYEQSSLLELIKTDNKVLNKVITVYAALCCEVKKLKHEAETKFYNGLLYYGEGVSDTSVVEGESQIQMGRFVSFLQELSCFVSRCFEVVVNMVHQLAALYNSSKGATKIIESTGVHFQTVYEHLGELLVVLITLDEIMENHATLKEHWKMYKRLLKSVHHNPAKFAIPEEKLKPFEKLIFKLEGQLLDSMIFQACVEQRFDNPGENVSVSKNSAFAEEFAYNIRTIFANVESKLGEPSEIDQRDKYTGVCGLFVLHFHIFRAVDKKIYKSLLDVCKKVPAVTLAANIIWFPDTFLINKVPAAAKLMDKKSLQSIRSSRDVFLQQKAQTLMKDMQSYYIFVTSWMMKMESILSKEPKPDKLSEDLSNRCNIFVQGILYAYSISTIIKTTMNMYMSMQRPMTKTSVKALCRLVELLKAVEHTFHRRSLVVADSVSHITQQLQSQALVSISMAKKRVISDKKYSEQRLDVLSALVLAENTLNGPSTKERRLIMSLALSVGTQMKTFKDEELLPLQLVLKKLDLISELRERVKVQCDCSFLYWHRTVFPIYLDDVYENAVDAARIHYMFSALRDCVPTMLHAKHMESCDQLLECYDTEIMEILNEHLLDKLCKEIEKDLRLSVHTHLKLDDRNPFKVGMKDLAHFFSLKPIRFFNRFIDIKAYVTHYLDKTFYNLTTVALHDWATYSEMRNLATQRYGLVMTEAHLPSQTLEQGLDVLEIMRNIHVFVSRYLYNLNNQIFIERTSNNKHLNTINIRHIANSIRTHGTGIMNTTVNFTYQFLRKKFYIFSQFMYDEHIKSRLIKDIRFFRETKDQTDQKYPFERAEKFNRGIRKLGLTPDGQSYLDQFRQLISQIGNAMGYVRMIRSGGLHCCSSAIRFVPDLEDIVNFEELVKEEGLSEETQKASSQLDCVLSDLTSNSAEGTEYFKMLVGVFAPEFRSIKNMHLRNFYMIVPPLTVNFVEHSISCKEKLNKKNKVGAAFTDDGFAMGVAYILKLLDQYQEFDSLHWFQAVREKYVKEMNAVVKEQNVQSTSQDEKLMQTMNLTQKRLDVYLQEFELLYFSLSSARIFFRADKTAAEETQEKKDKEEGAKTGPVSMTAEGSPVEPSAK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***::*****:***.********:***:*** :***** :**: **:**** *******.****:*****************:*****************:****:***********:****.:*:*:***:.*******:**********:**:***:*::******* *.* ..****:*******:********.**:*****::** ***:**.*************:**.* *********:::********.******:**:**. . .:******:******:.**:******:**************.*:********:***::***:******:******:**:********.***:*:******:*:****:*: **.*******:* **:****:**:********:**** : *.::***:****:*:**:***************:*****:*************:*****:** *:***:***********:** *** ***:***********************************:****:******************:***:*:*************:.****.******:******************:************:*:*::*:** : **:***.***:************************************* **** ****:***********:****************************************************************:*******************************************************:**************************** ***.*:****:*************:**:*********************:**********.*.************.**********:*** :*: :**.**** * *************.******* **:******:******:******************:*************** *******:*********:*****:**:.**.*:*****:******:**********:*****************************.****:*** :**. . . . ..:* .*", "identical_positions": 978, "similar_positions": 157, "identity": "83.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100427-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BP01-1", "uniprot_id": "VMAC_MOUSE", "id": "Q8BP01-1", "name": "Vimentin-type intermediate filament-associated coiled-coil protein", "aln": "MSAPPPLQIREANAHLAAVHRRAAELERRLLAAERTIGAQAERLACHDQHLRAALDELGRAKDREISALQEQLLSSEATVRSLQAAVDQRDQMIQQLQPRADLLQDITRHRPPLAALLATLEEAEELGPLP-ASHSHRAQLLPDGPG--PP--LGNNMGKEEGQDDQDDQ--QPAVFGTTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2NL98-1", "uniprot_id": "VMAC_HUMAN", "id": "Q2NL98-1", "name": "Vimentin-type intermediate filament-associated coiled-coil protein", "aln": "MSAPPALQIREANAHLAAVHRRAAELEARLDAAERTVHAQAERLALHDQQLRAALDELGRAKDREIATLQEQLMTSEATVHSLQATVHQRDELIRQLQPRAELLQDICRRRPPLAGLLDALAEAERLGPLP-ASD--PGHPPPGGPG--PP--LDNSTGEEA---DRDHL--QPAVFGTTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QC89-1", "uniprot_id": "A0A2R8QC89_DANRE", "id": "A0A2R8QC89-1", "name": "", "aln": "MSSPSPVQIREANAHLAALHRRVSELEQRLREAERTVREQAESLIRKDEQLRAATQEITEAKDKEIFFLHEKLCQSEESIHKLNQTIKEKDSLIGQLQHRCQLLDNICKSRPLLDSMLAQMAEAERMGPVSDLGKPTTNSSLTDGESNCSPSRLSNHKDFSLSEDDSDDQELDGVVFGTTV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*..:***********:***.:*** ** ****: *** * :*::**** :*: .***:** *:*:* ** :::.*: ::.::*.:* *** *.:**::* : ** * .:* : ***.:**:. .. ..* . .* *.* . . * *. : .******", "identical_positions": 77, "similar_positions": 53, "identity": "42.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100427-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99748-1", "uniprot_id": "NRTN_HUMAN", "id": "Q99748-1", "name": "Neurturin", "aln": "-----------MQRWK---AAALASVLCSSVLSIWMCREGLLLSHR-LGPALVPLHRLPR--TLDARIARLAQYRALLQGAPDAMELR-ELTPWAG----RPPGP-RRRAGP-----RRRRARARLGARPCGLRELEVRVSELGLGYASDETVLFRYCAGACEAAARVYDLGLRRLRQRRRLRRERVRAQPCCRPTAYEDEVSFLDAHSRYHTVHELSARECACV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97463-1", "uniprot_id": "NRTN_MOUSE", "id": "P97463-1", "name": "Neurturin", "aln": "-----------MRRWK---AAALVSLICSSLLSVWMCQEGLLLGHR-LGPALAPLRRPPR--TLDARIARLAQYRALLQGAPDAVELR-ELSPWAA----RIPGP-RRRAGP-----RRRRARP--GARPCGLRELEVRVSELGLGYTSDETVLFRYCAGACEAAIRIYDLGLRRLRQRRRVRRERARAHPCCRPTAYEDEVSFLDVHSRYHTLQELSARECACV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LN78-1", "uniprot_id": "A0ABK0LN78_RAT", "id": "A0ABK0LN78-1", "name": "Neurturin", "aln": "---GARRERRESARWLRPCAPRPALLAWSRVLSALQPPTGAALGCTEPGEPWEDREREARGGTLWPGPC-PAPCAVASSGTGSPGRLRSPRSGWRT----QWLGPGRARVAG-----GVTTDLVIWSLRQAKAQD-EVRVSELGLGYTSDETVLFRYCAGACEAAIRIYDLGLRRLRQRRRVRKERVRAHPCCRPTAYEDEVSFLDVHSRYHTLQELSARECACV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AC58GRP2-1", "uniprot_id": "A0AC58GRP2_DANRE", "id": "A0AC58GRP2-1", "name": "Neurturin", "aln": "MGNMRGPNASPHSKMKLWKFAAIGLILCGAALLLLVLKVTPSSRAPPLPSSSSTSLTVSNSSSSIEFGGRQRRTRSADGENSLVSEFMEMFQSFTEGELKQVIGTLVERKAHRDAQLSKRTKRAKKGSKPCSLRKLVVTVSQLGIAFVSDETIAFHYCSGECDASRKNYDFVLEAMKKKGLLRKNKARHRPCCRPTAYEEDFLFLDNSFQYKTIHEFSAKACGCI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . * . .. : .: : : *. * . . : . :. * **:**:.:.****: *:**:* *:*: : **: *. :::: :*:::.* :*********::. *** :*:*::*:**: *.*:", "identical_positions": 42, "similar_positions": 53, "identity": "18.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100504-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IZ52-1", "uniprot_id": "CHSS2_HUMAN", "id": "Q8IZ52-1", "name": "Chondroitin polymerizing factor, non-catalytic subunit", "aln": "MRASLLLSVLRPAGPVAVGISLGFTLSLLSVTWVEEPCGPGPPQPGDSELPPRGNTNAARRPNSVQPGAEREKPGAGEGAGENWEPRVLPYHPAQPGQAAKKAVRTRYISTELGIRQRLLVAVLTSQTTLPTLGVAVNRTLGHRLE-RVVFLTGARGRRAPPGMAVVTLGEERPIGHLHLALRHLLEQHGDDFDWFFLVPDTTYTEAHGLARLTGHLSLASAAHLYLGRPQDFIGGEPTPGRYCHGGFGVLLSRMLLQQLRPHLEGCRNDIVSARPDEWLGRCILDATGVGCTGDHEGVHYSHLELSP-GEPVQEGDPHFRSALTAHPVRDPVHMYQLHKAFARAELERTYQEIQELQWEIQNTSHLAVDGDQAAAWPVGIPAPSRPASRFEVLRWDYFTEQHAFSCADGSPRCPLRGADRADVADVLGTALEELNRRYHPALRLQKQQLVNGYRRFDPARGMEYTLDLQLEALTPQGGRRPLTRRVQLLRPLSRVEILPVPYVTEASRLTVLLPLAAAERDLAPGFLEAFATAALEPGDAAAALTLLLLYEPRQAQRVAHADVFAPVKAHVAELERRFPGARVPWLSVQTAAPSPLRLMDLLSKKHPLDTLFLLAGPDTVLTPDFLNRCRMHAISGWQAFFPMHFQAFHPAVAPPQG--PGPPELGRDTGRFDRQAASEACFYNSDYVAARGRLAAASEQEEELLESLDVYELFLHFSSLHVLRAVEPALLQRYRAQTCSARLSEDLYHRCLQSVLEGLGSRTQLAMLLFEQEQGNST", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IQX7-1", "uniprot_id": "CHSS2_MOUSE", "id": "Q6IQX7-1", "name": "Chondroitin-polymerizing factor, non-catalytic subunit", "aln": "MRASLLLSVLRPAGPVAVGISLGFTLSLLSVTWVEEPCGPGPPQPGDSELPPRGNTNAARRPNSVQPGSERERPGAGAGTGESWEPRVLPYHPAQPGQATKKAVRTRYISTELGIRQKLLVAVLTSQATLPTLGVAVNRTLGHRLE-HVVFLTGARGRRTPSGMAVVALGEERPIGHLHLALRHLLEQHGDDFDWFFLVPDATYTEAHGLDRLAGHLSLASATHLYLGRPQDFIGGDTTPGRYCHGGFGVLLSRTLLQQLRPHLESCRNDIVSARPDEWLGRCILDATGVGCTGDHEGMHYNYLELSP-GEPVQEGDPRFRSALTAHPVRDPVHMYQLHKAFARAELDRTYQEIQELQWEIQNTSRLAADGERASAWPVGIPAPSRPASRFEVLRWDYFTEQYAFSCADGSPRCPLRGADQADVADVLGTALEELNRRYQPALQLQKQQLVNGYRRFDPARGMEYTLDLQLEALTPQGGRWPLTRRVQLLRPLSRVEILPVPYVTEASRLTVLLPLAAAERDLASGFLEAFATAALEPGD-AAALTLLLLYEPRQAQRAAHSDVFAPVKAHVAELERRFPGARVPWLSVQTAAPSPLRLMDLLSKKHPLDTLFLLAGPDTVLTPDFLNRCRMHAISGWQAFFPMHFQAFHPAVAPPQG--PGPPELGRDTGHFDRQAASEACFYNSDYVAARGRLVAASEQEEELLESLDVYELFLRFSNLHVLRAVEPALLQRYRAQPCSARLSEDLYHRCRQSVLEGLGSRTQLAMLLFEQEQGNST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F9K2-1", "uniprot_id": "E7F9K2_DANRE", "id": "E7F9K2-1", "name": "Hexosyltransferase", "aln": "MRISMLVSLIRPSGPIIVGISLGFTLSLLSVTWVDESCDSDWMGADEMLIGQPGSLKGARKPSSISSGTN-----DNGNAEEDFEPRIVPYNKPAQDGPPKKVFRAKYASTELGIRERLFVAVFTSKTTLNTLAVAVNRTLNHHLDGHLVFFTGTRNRKIPNGMSVVAHGDDRPVPNMFQSVRYLLDHHIAEFDWFYFVQDDTYTQPQRLKRLVSHLSMD--LQLYMGHSGEFIG-AETQGRYCYGGPGFLLSRALLLKLQPFLEHCRTDIISVRPDEWLGRCIIDYAGVNCVEEYEGVNYNYFRMENNMDFLRMENDRFQKALTVHPVSSADLMYRLHKHFTEIELQRTYEEIEKLQSEIKNVSEVAADGNKSALWPIGITPPFEPKNRFEVLRWDYFTEENLFSCLDDAPKCTINGADRVDVIDVIKVAAEELNKKYNPFVQLSEPHLVNGYRRLDHTRGMEYTLDLQFQATTESGHQKSITRRVHLVRPLSQVEIIPMPYVTEATRINILLPISSYESHAALRFLDHCSTNLFETSE-NAVLNFLFTYEPAEAQKVSTNDVFKEVKAKITAVESRYPNVKVSWISIKTESPGVLRILDIVSRKHPVETLFLLATVDTVFNSEFLNRCRMNAINGWQVFFPIHFQEFDPIVAYPDQTPPSSPDLLREAGHFDRYTFEEACFYNSDYMSARTRMPGDLQENEELLESLDLYDVFVQYSGLHVFRAVEPALRQAYRNRTCDPRLSEDVFHRCLQSTLESHGSRSQLAMLIFEQEQGNST", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *:*:*::**:**: *****************:*.*... ..: : *. :.**:*.*:..*:: . .: *.:***::**: . . ..**..*::* *******::*:***:**::** **.*******.*:*: ::**:**:*.*: * **:**: *::**: ::. ::*:**::* :****::* * ***:.: * **..***: :**:*:. :*** * ****:** *.**** ** :*:*.** **.**:*.**********:* :**.*. ::**::*.::.:. : :: : :*:.***.*** .. **:*** *:. **:***:**::** **:*.*.:*.**:::: **:**..* .* .************: *** *.:*:*.:.***:.** **: .* ****::*:* ::*.: :*******:* :**********::* * .* : .:****:*:****:***:*:******:*:.:***::: * . * **: :* :*..: *.*.:*: *** :**:.: *** ***::: :* *:*..:*.*:*::* :*. **::*::*:***::****** ***:..:*******:**.***.***:*** *.* ** *: *..*:* *::*:*** : .*********::** *: . :::********:*::*:::*.***:******* * ** :.*..*****::*** **.**. ***:*****:*********", "identical_positions": 402, "similar_positions": 255, "identity": "51.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100504-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IZ52-1", "uniprot_id": "CHSS2_HUMAN", "id": "Q8IZ52-1", "name": "Chondroitin polymerizing factor, non-catalytic subunit", "aln": "MRASLLLSVLRPAGPVAVGISLGFTLSLLSVTWVEEPCGPGPPQPGDSELPPRGNTNAARRPNSVQPGAEREKPGAGEGAGENWEPRVLPYHPAQPGQAAKKAVRTRYISTELGIRQRLLVAVLTSQTTLPTLGVAVNRTLGHRLERVVFLTGARGRRAPPGMAVVTLGEERPIGHLHLALRHLLEQHGDDFDWFFLVPDTTYTEAHGLARLTGHLSLASAAHLYLGRPQDFIGGEPTPGRYCHGGFGVLLSRMLLQQLRPHLEGCRNDIVSARPDEWLGRCILDATGVGCTGDHEGVHYSHLELSP-GEPVQEGDPHFRSALTAHPVRDPVHMYQLHKAFARAELERTYQEIQELQWEIQNTSHLAVDGDQAAAWPVGIPAPSRPASRFEVLRWDYFTEQHAFSCADGSPRCPLRGADRADVADVLGTALEELNRRYHPALRLQKQQLVNGYRRFDPARGMEYTLDLQLEALTPQGGRRPLTRRVQLLRPLSRVEILPVPYVTEASRLTVLLPLAAAERDLAPGFLEAFATAALEPGDAAAALTLLLLYEPRQAQRVAHADVFAPVKAHVAELERRFPGARVPWLSVQTAAPSPLRLMDLLSKKHPLDTLFLLAGPDTVLTPDFLNRCRMHAISGWQAFFPMHFQAFHPAVAPPQGPGP--PELGRDTGRFDRQAASEACFYNSDYVAARGRLAAASEQEEELLESLDVYELFLHFSSLHVLRAVEPALLQRYRAQTCSARLSEDLYHRCLQSVLEGLGSRTQLAMLLFEQEQGNST", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IQX7-1", "uniprot_id": "CHSS2_MOUSE", "id": "Q6IQX7-1", "name": "Chondroitin-polymerizing factor, non-catalytic subunit", "aln": "MRASLLLSVLRPAGPVAVGISLGFTLSLLSVTWVEEPCGPGPPQPGDSELPPRGNTNAARRPNSVQPGSERERPGAGAGTGESWEPRVLPYHPAQPGQATKKAVRTRYISTELGIRQKLLVAVLTSQATLPTLGVAVNRTLGHRLEHVVFLTGARGRRTPSGMAVVALGEERPIGHLHLALRHLLEQHGDDFDWFFLVPDATYTEAHGLDRLAGHLSLASATHLYLGRPQDFIGGDTTPGRYCHGGFGVLLSRTLLQQLRPHLESCRNDIVSARPDEWLGRCILDATGVGCTGDHEGMHYNYLELSP-GEPVQEGDPRFRSALTAHPVRDPVHMYQLHKAFARAELDRTYQEIQELQWEIQNTSRLAADGERASAWPVGIPAPSRPASRFEVLRWDYFTEQYAFSCADGSPRCPLRGADQADVADVLGTALEELNRRYQPALQLQKQQLVNGYRRFDPARGMEYTLDLQLEALTPQGGRWPLTRRVQLLRPLSRVEILPVPYVTEASRLTVLLPLAAAERDLASGFLEAFATAALEPGD-AAALTLLLLYEPRQAQRAAHSDVFAPVKAHVAELERRFPGARVPWLSVQTAAPSPLRLMDLLSKKHPLDTLFLLAGPDTVLTPDFLNRCRMHAISGWQAFFPMHFQAFHPAVAPPQGPGP--PELGRDTGHFDRQAASEACFYNSDYVAARGRLVAASEQEEELLESLDVYELFLRFSNLHVLRAVEPALLQRYRAQPCSARLSEDLYHRCRQSVLEGLGSRTQLAMLLFEQEQGNST", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1R7L6-1", "uniprot_id": "F1R7L6_DANRE", "id": "F1R7L6-1", "name": "Hexosyltransferase", "aln": "MRFSMLISLLRPIGPVIIGISLGFTLSLLSVSWVEESCDVNAVGDEGIALNQDGSLKGARRPNSISTGNDGE-----EEEKEDFPPRIIPYKPVKQTQP-KKLFRAKYISTELGIRERLFVGIITSKNTINTLGVAVNRTIGHHLDNVVFFTGTRNRKIPHGMNVVTHGDERLIWNMFQTIKYILEHYITEYDWFYLAQDDTYTQADRIKALVGHLSMD--RVLYMGSPEEFIGG-EMQGRYCYGGFGYLLSRSLLLKLQPFLENCRNDILSARHDEWLGRCIIDYANTNCVEEFEGQRYYYYEMGKNSDPSKEDNVQFKNALTVHPVSDPEQMYRLHKHFTEIELRKTYEEIEKLQAEIRNVSVVAFEGNRSALWPVGINPPFEPKTRFEVLRWDYFTEDQVYSCIDGSPKCELRGVDKLDVADVIETAMGELNKKYKPVLYLKKQQLINGYRRFDPTRGMEYTLDLQLEVVNQKGHSRSITKRVHLVRPLSRIEIIPMPYVTEATRVHIILPVTLQDRDYVHQFLEVYATNAFETSE-NAILTFLFIYDPIEAQQVNQNDIFSSIKAQISTYEHRYPAVKIPWISVKSESPSQIKFMDIISKKHPVDTLFFIATVKTSISSEFLNRCRMNSINNWQVFFPIHFQYYNPDIAYHNQPLPSALDLVKEAGLFDRSSFTEACFYNSDYMATRTRMSSDVLENEEILENLDIYDMFVKYSGLHVFRAVEPALHQKYSYQTCNPRLSEEIYQRCVQSTLDSLGSRSQLAMLLFEQEQGNST", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *:*:*:*** *** :*************:****.*. .. . * *. :.******:..* : * *.: **::**:*.: *. ** .*::*********::*:*.::**: *: *********:**:*:.***:**:*.*: * ** **: *:** * ::. :::::**:: ::***:*. * ***:*. : *.****: **:* *::**** ****:**** **** ** :*:*.**.*****:*** ********:* :...*. :.** :* : *:. .:* :*.: :*:.***.*** ** :**:*** *:. ** :**:**::** **:*.* :* :*:::: ***** .* .* :************: .:** ****:* ***.*: *****: **: ***::*:*.* *:****:********:************.:. :* .:*:**:*:*****:**:*:******:*: ::**:: :** . ***.:** *:*..: * **:*::*:* :**:. : *:*:.:**::: *:*:*..::**:**:: :** :::**::*****:****::* .* ::.:*******::*..**.***:*** ::* :* : * * :* :::* ***.: :*********:*:* *: : ::**:**.**:*::*:::*.***:******* *:* *.*..****::*:** **.*:.****:***************", "identical_positions": 408, "similar_positions": 237, "identity": "52.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100505-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63259-1", "uniprot_id": "PTPRN_RAT", "id": "Q63259-1", "name": "Receptor-type tyrosine-protein phosphatase-like N", "aln": "---------------------------------------------------------------------------------------------------------------------------MRRPRRPGGPAG---------CGGSEGSGGLRLLVCLLLLSGRPGGCSAISAHGCLFDRRLCS-HLEVCIQDGLFGQCQAGVGQARPLLQVTSPVLQR---LQGVLRQLMSQGLSWHDDLTQYVISQEMERIPRLRPPEPHPRDRSGSVPRRAGPAGELLSQGNPTGSSPAVQG-LSRPPGDGNGAGVGSPLSSLQ-AELLPPLLEHLLMPPQPPHPS---------------------------------------------------------------LTYEPALLQPYLFQQFGSRDGSRGSESASGVV--GHLAKAEDPVLFSRSLSKAILGTHSGHSFGDLTGPSPAQLFQDSGLLYMAQELPVPGRARAPRLPEEGGSSRAEDSSE-----GHEEEVLGGHGEKSPPQAVQADVSLQRLAAVLAGYGVELRQLTPEQLSTLLTLLQLL----------------PKGTGRHLGGAVN-GGADVKKTIEEQMQRG-DTADARPPTPLLPGHPTASSTSIKVRQVLSPGFPEPPKTSSPLGISAVLLEKKSPLGQSQPTVVGQPS------ARPSAEEYGYIVTDQKPLSLVAGVKLLEILAEHVHMTSGSFINISVVGPAVTFRIRHNEQN----LSLADVTQQAGLVKSELEAQTGLQILQTGVG------QREESAAVLPRQAHGISPMRSLLLTLVALAGVAGLLVALAVALCMRHHSKQRDKERLAALGPEGAHGDTTFEYQDLCRQHMATKSLFNR------AEGQPEP-------------SRVSSVSSQFSDAAQASPSSHSSTPSWCEEPAQANMDISTGHMILAYMEDHLRNRDRLAKEWQALCAYQAEPNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWPDEGSSLYHVYEVNLVSEHIWCEDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRGR-SCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEVNAILKALPQ----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60673-1", "uniprot_id": "PTPRN_MOUSE", "id": "Q60673-1", "name": "Receptor-type tyrosine-protein phosphatase-like N", "aln": "---------------------------------------------------------------------------------------------------------------------------MRRPRRPGG------------SGGSGGSGGLRLLVCLLLLSGRPGGCSAISAHGCLFDRRLCS-HLEVCIQDGLFGQCQAGVGQARPLLQVTSPVLQR---LQGVLRQLMSQGLSWHDDLTQHVISQEMERIPRLRPPEPHPRDRSGLVPRKPGPAGELLTQGNPTGSSPAAQG-FPRPAGGRSWG--GSPLSSLQ-AELLPPLLEHLLMPPQPPHPA---------------------------------------------------------------LTYEPALLQPYLFHQFGSRDGSRGSESSSGVVGVGHLSKAEGPALFSRSASKAILGTHSGHSFGDLTGPSPAQLFQDSGLLYMAQELPVPGRARAPRLPENGGN-RAEDSSE-----GHEEEVLGGRGEKSPPQAAQPELSLQRLTAVLAGYGVELRQLTPEQFSTLLTLLQLL----------------PKGTGRNLEGAVNVGGADVKKTIQ-QMQRG-DPAEALPPTPSLPGYLTASPASSEVQQVLSPGFPEPPHTPSPLGSSSVLLEKKSPLGQSQPTVVGRPS------ARPSAEEYGYIVTDQKPLSLVAGVRLLEILAEHVHMSSGSFINISVVGPAVTFRIRHNEQN----LSLADVTQQAGLVKSELEAQTGLQILQTGVG------QREEAAEVLPRQAHGISPMRSVLLTLVALAGVAGLLVALAVALCMRHHSRQRDKERLAALGPEGAHGDTTFEYQDLCRQHMATKSLFNR------AEGQPEP-------------SRVSSVSSQFSDAAQASPSSHSSTPSWCEEPAQANMDISTGHMILAYMEDHLRNRDRLAKEWQALCAYQAEPNTCAAAQDESNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWPDEGSSLYHVYEVNLVSEHIWCEDFLVRSFYLKNLQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRGR-SCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEVNAILKALPQ----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16849-1", "uniprot_id": "PTPRN_HUMAN", "id": "Q16849-1", "name": "Receptor-type tyrosine-protein phosphatase-like N", "aln": "---------------------------------------------------------------------------------------------------------------------------MRRPRRPGG---------------LGGSGGLRLLLCLLLLSSRPGGCSAVSAHGCLFDRRLCS-HLEVCIQDGLFGQCQVGVGQARPLLQVTSPVLQR---LQGVLRQLMSQGLSWHDDLTQYVISQEMERIPRLRPPEPRPRDRSGLAPKRPGPAGELLLQDIPTGSAPAAQHRLPQPPVGKGGAGASSSLSPLQ-AELLPPLLEHLLLPPQPPHPS---------------------------------------------------------------LSYEPALLQPYLFHQFGSRDGSRVSEGSPGMVSVGPLPKAEAPALFSRTASKGIFGDHPGHSYGDLPGPSPAQLFQDSGLLYLAQELPAPSRARVPRLPEQGSSSRAEDSPE-----GYEKEGLGDRGEKPASPAVQPDAALQRLAAVLAGYGVELRQLTPEQLSTLLTLLQLL----------------PKGAGRNPGGVVN-VGADIKKTMEGPVEGR-DTAELPARTSPMPGHPTASPTSSEVQQVPSPVSSEPPKAARPP-VTPVLLEKKSPLGQSQPTVAGQPS------ARPAAEEYGYIVTDQKPLSLAAGVKLLEILAEHVHMSSGSFINISVVGPALTFRIRHNEQN----LSLADVTQQAGLVKSELEAQTGLQILQTGVG------QREEAAAVLPQTAHSTSPMRSVLLTLVALAGVAGLLVALAVALCVRQHARQQDKERLAALGPEGAHGDTTFEYQDLCRQHMATKSLFNR------AEGPPEP-------------SRVSSVSSQFSDAAQASPSSHSSTPSWCEEPAQANMDISTGHMILAYMEDHLRNRDRLAKEWQALCAYQAEPNTCATAQGEGNIKKNRHPDFLPYDHARIKLKVESSPSRSDYINASPIIEHDPRMPAYIATQGPLSHTIADFWQMVWESGCTVIVMLTPLVEDGVKQCDRYWPDEGASLYHVYEVNLVSEHIWCEDFLVRSFYLKNVQTQETRTLTQFHFLSWPAEGTPASTRPLLDFRRKVNKCYRGR-SCPIIVHCSDGAGRTGTYILIDMVLNRMAKGVKEIDIAATLEHVRDQRPGLVRSKDQFEFALTAVAEEVNAILKALPQ----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BD60-1", "uniprot_id": "A0A8M2BD60_DANRE", "id": "A0A8M2BD60-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------MRSAR-------------------------LWMLVCLATACCQLG---TGDKYGCLFDEGLCS-RGEICWDDELFGQCLAER-QERFRYRVTAVLLDR---LQSLLQTLMKEGLTWQDDVTQSVIKKELSKVPKIP-----------------------LSSGTKNGPSIESQS---------------GSTNQLN-SKQAHPYMDYMIVD--PPQSS---------------------------------------------------------------LHMQS--LDPYSYQRYGYQDEE---ERSLNLVEKGRYPASSSRVRGNPPVPPSLD--KDDQLLQDLMTLLLSSPAQPSSRHRVAAPHSTSSFFQDLDFPLEYKDYNKDTFSQDERISSQREPKKGPQKYGSFSAHSAAGTSQQGLNELLLQHGFDLNHLNPEEMERLFSVLQFLQNE-------------PPNNQRKSEAKDSSAPPKVMKITEGEMTHVVEKASSPASNSSSPPLKPGPQTSPKSPGSPGASKDNSIPTGASVLGPLTLKQEEGPLGKGALSVQPGKN------KTKIKEEFGYIVTNQSPLNLSDGVHLLKTLAERIHLTTDSFINISVVGPAVTFRVLPNSQN----LTASEISEKTVAQKNLLETETGLKVLQAGVG------EKSE-GHALPVATRVRDNTQWVFLMFVGVACLGGLLVGALTIACLRTHARHLASGKLG-LGPEAGN-VTHYEYQDLCRQHMAAKSSLGRQDCGVGAAGGAGPGAVGGGGGGGTDTSRVSSVSSQFSDAPQPSPSSHSSTPSWCEEPAQSNMDISTGHMILAYMEDHLKNKDRLLKEWEALCSYQAEPSTISAAQSESNIKKNRCSDAVPYDHSRVKLKAEINPSRTDYINASTIIEHDPRMPAYIATQGPLSHTISDFWQMVWESGCTVIVMMTALVEDGEKQCDRYWPDEGSSLYHIYEVNLVSEHIWCNDFLVRSFYLKNVQTQETRTLTQFHFLSWPAQGIPTSTRPLLDFRRKVNKCYRGR-SCPIIVHCSDGTGRTGTYILIDMVLNRMAKGVKEIDIAATLEHIRDQRPGMVRTKDQFEFALTAVAEEVNAILKALPQ----------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPV8-1", "uniprot_id": "Q9VPV8_DROME", "id": "Q9VPV8-1", "name": "", "aln": "MPAVGTSCGVPIIMARNVQQRQQHPCTTTEEPKHQRARGTAGHQESATGECQQFWSKQRPPFDQQQQQEDQDPEQDPQQHPSTPQESVHHHRSPRQHELLHHQRKVPPTLPARGRHLISEGARRREVRGCGAGGGGLLCCSLDALSRPAKLLQFGVLLLILLLATHGDLAQAEGNVGCQFVRTLCIPHSEVCYDDNIFGKCIPTTGVDVEDIEKTPLTEDQSRVLATMLEELQGAGLGWDHPYVQCRIQGSLFSLQRQQQLPPNLCANLAPTPPEFGDPASALAYVRFTPPEPEAELDYYEQPAGPAQFYPALRKKQVRESDADDMYLNRMLQDRRRLRHDPSELEHFGKMDGHGQSTQLDAPSIMDAFLDTERQRIEREQQLAAAEQDADRRAEQNRLELYQILAASEPDPQPYQRKPAAQPNAMDQLEAIVEQQQQRELKEQQEQAKAPVYVPPEEVNESSELYFPDNFAPFKRARGRSRGGLAEEVEDEQPKRSFFRELAGEQGLVQEPPLRFRHVETEVDATPELVKRRPASFKQLDPYDVSLQQQEMAFESGLLRNSLTPLEEEAMLASNSFPRQAKSQRVYTEGGLLLMPQDEQDTDGMQADEPENVKQSLLANMLGFARHERLDVKKPGPLLGPPSLGSAELSNQLETEKAHKQKGHGNKEVLPAHIKGNDEDDAHKKKKVMKQQHSAEDHAPHTVDTEYVHVFVKNPIDSWNDGQRIMKELEQILHMQG-YFSYLTVQQHEVSFRVNSNNPERKTAGDVARTINENRGVKNNIQRRVGFYVLHAGVGDVIKDLQDPSVSSSRIELAEQGPDVTHIMAYMFAGAGAAAVIVIFVTLILIKRHDRKRDK-LGGLQSGIAGAETCSKDYQELCRARMAGKAGGGGNSTGGAAGGGSNE------------PAPSGRITSLSKENEGRPPSSRSSTSSWSEEPALTNMDISTGHMVLSYMEDHLRNKGRLQREWEALCRYEAEPSAREAASQPQCAGLNRPGAPLPYDHSRVVLNHLANAEGLDYVNASTITDHDPRAPAYVAAQGPLPSTLAHFWQMIWEQGAVVIVALCRLQENGEVACARYWPEEGAEVYHIYEVHLVSEHIWCDDYLVRSFYLKNLRTSETRTVTQFHFLSWPHMGVPAQAKALLDFRRKVNKSYRGRRSCPIVVHGSAGAGRTGVYILLDLVLERMNKGAREIDIAATLEHLRDQRAGVVATRQQFEFVLMAVAEEVHAILKALPANTSGEKRELDKDPVVGGGSSSTTTKEPLKEDKAQEAAEEEAPTSSSKAAAAAKKEKEKDKDKEEKQAKDQAKVAEPRTPAKSAKQAKK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : :*: : . : . : . ** * . ** : *:* :* :**:* . *. :: * :*. * ** *.. .* *. .: : : * . . : . :. :. :: :: : * . :** : . : * . . . * : . . :. : . : . . : *. . *.* : . ::: .: :. . .: : : .. .. :: : . : :. .: .* *: ::...: . * :::: * : :*: * ::* ::**: *. : : :: *. :: ..*: :*::*** : . . :. :: :.. * ..::* . :: * :: . . . .. :**:*** :** *: . * * . : . ::* .: .***:***.**.**** :*********:*:******:*:.** :**:*** *:***.: :*. ** :****:*: *: ... **:***.* :**** ***:*:****. *::.****:**.*..*** : * *:* * ****:**:.:**:***:********:*:*********::*.****:********* * *:.::.**********.**** ****:** * *:****.***:*:**:** **.:**********:****.*:* :::****.* ******:******* ", "identical_positions": 259, "similar_positions": 235, "identity": "19.43%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100513-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AXU1-1", "uniprot_id": "BTBDG_RAT", "id": "Q6AXU1-1", "name": "BTB/POZ domain-containing protein 16", "aln": "-------------MKMLNSR----------------KIRMERRIVGATNRWRFP-------------------------QDHFCGDLLALSQMCNVLNVDLDDALKNPDKLCISKFQKLFTESIMDSGTQSGE---------------ADVILDCLGFKWELHHPQIFQSETLAKLYLTALIQNTKSSQRDLEKILKVHSTERMK-----KRSPVKKIIISLRINDPAVTRVAFALALKNLYMNEVEMTVDNVLGVLASAHILQFNRLFRKCVSTMLNRLTPCTIKNFYLAGCKYKEEQLTNACEKWLAMNLVPLVGTQIHLRHIPEPLLYKVLKSPRLFTFSEFHLLKTLLMWVYLQMNGKVQTLPIHETMLAFFSSFPKKSCFLEQDPGHSWMPLFLCLRLHGITSGKDLEEIKHINFFPESWLVRVTANHYHALESGGNMVHLKDLSTQAMRFGLLFRQEYTTYSETISIYGYFFEIKGIKHDTT-SYSFSMQRIRHTDLECPSSVCEHSTISLRSERLVKYEIRAQTLVDGRWQEFGTNQIMQKFGFIKPGCKSHALKIQTVGIPIYASFAFIFPAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q173-1", "uniprot_id": "BTBDG_MOUSE", "id": "E9Q173-1", "name": "BTB/POZ domain-containing protein 16", "aln": "-------------MKMLNSVSGSFRKKAGDSRSRECRTRLERRIVGATNRWRFP-------------------------QDHFCGDLLALSQMCNVLNVDLDEALKNPDRLCISKFQKLFSENIMNSGTQSGE---------------ADVILECLGFKWELHHPQIFQSGTLAKLYLTALIQNMKSSQRELDKVQKAHPSGKIK-----KRSPVKKIIISMRINDPAVTRVAFALALKNLYMKEVEMTVDNVLGVLASAHILQFNRLFQKCVNMMMNRLAPSTIKNFYLAGCKYEEEQLTMACEKWLAMNLVPLVGTQIHLRQIPEPLLYKVLKSPRLFTFSEFHLLKTLLMWVYLQMNCKVQMVPIHETILAFFNSFPKKCCFLEQDPGQNWMPLFLCLRLHGITSGKDLEVLKHINFFPESWLVRVTANHYHALESGGNMVHLKDLSTQAMRFGLLFRQEYTTYSERISIYGYFFEIKGIKHDPT-SYSFSMQRIKHTDLECPSPVCEHSTISLRSERLVKYEIQAQTLVDGRWQEFRTNQIMQKFGFIKPGCKSHVLKIQTVGIPIYASFAFIFPAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q32M84-1", "uniprot_id": "BTBDG_HUMAN", "id": "Q32M84-1", "name": "BTB/POZ domain-containing protein 16", "aln": "-------------MIMSNTH----------------KARLERRVTGSTNRWRLP-------------------------KQPFSGDLLSLSQMCKALSIDFEEALRNPDRLCISQIQKFFFENFKNKDIQSGE---------------ADVILECLGFKWELHQPQLFQSETLAKLYLKALAQGTTHPLRELEELLRAQSPKKTK-----EKSPAKRIIISLKINDPLVTKVAFATALKNLYMSEVEINLEDLLGVLASAHILQFSGLFQRCVDVMIARLKPSTIKKFYEAGCKYKEEQLTTGCEKWLEMNLVPLGGTQIHLHKIPQDLLHKVLKSPRLFTFSEFHLLKTMLLWVFLQLNYKIQAIPTYETVMTFFKSFPENCCFLDRDIGRSLRPLFLCLRLHGITKGKDLEVLRHLNFFPESWLDQVTVNHYHALENGGDMVHLKDLNTQAVRFGLLFNQENTTYSKTIALYGFFFKIKGLKHDTT-SYSFYMQRIKHTDLESPSAVYEHNHVSLRAARLVKYEIRAEALVDGKWQEFRTNQIKQKFGLTTSSCKSHTLKIQTVGIPIYVSFAFIFPAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TNA7-1", "uniprot_id": "A0AB32TNA7_DANRE", "id": "A0AB32TNA7-1", "name": "BTB/POZ domain-containing protein 16", "aln": "MHIQWSPSTGKNMTFRPNTRSVMITTQPNTTRNVSARSLCQRTQAGHTNRWQLAGALGSDLLGQAQIQRAEEFANKSPERKIKSADPMALHWHEDATSCPQSPLPRLVHPLSASRRTRLCKDVTWSSKLHTPEERFHVLSRKVTNNSNPDAVLECLGVRWELHCAVLSSSDTLCELYTSSKRQRDVQLHERAVKASRASSSAHGKGLVYRNWHLSGLLILRLPVKDASINKEALSFALRILYDPE-ERPDEWGEAVLSAAALLGMSNLFQKCLKKMMADISSSNVCSFHQASCKFKETFLQRACERWLELFFVTELSSHIKLKDLPFDLLLKTLRSPRLFAPNEYEVLRVVLYWLYLQLNPLRQTPPAHSTVITFFS--RETTVFLELPQGQKYITAFQALRMHGITEWQHLQELKNIRVLPESWLLNILSNHYHTLYSGGDMIVT-DFSKQAMRFGMMLNQEQECCTQTINLYGFYFILQAAKMGQSNTYIFSIERLRHWDPAVPQSSAVSHPYCMRADRSVRFHITVQSYANGEWQEHSSGTVNQHFGLCKRLSRSKPFQIEGLSPPILVTFALAFPCC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : :* .* ****::. :. ..* ::* .. . . : . *. *: :: : .. :: * .*.:*:***.:**** . : .* **.:** .: * . : :. .. : * : :*: : ::*. :.: *:: **: ** * * : .**::* :* :. **::*:. *: : ...: .*: *.**::* * .**:** : :*. .::*:*:.:* ** *.*:*****: .*:.:*:.:* *::**:* * * :.*:::**. :. **: *:. . * .**:****. :.*: ::::..:***** .: ****:* .**:*: *:..**:***:::.** :: * :**::* ::. * . : :* * ::*::* * *.. .:*: * *::.* .:: .:*.***. :. : *:**: . .:*: ::*: :. ** .:**: **..", "identical_positions": 142, "similar_positions": 196, "identity": "24.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100514-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1IGU3-1", "uniprot_id": "ARH37_RAT", "id": "A1IGU3-1", "name": "Rho guanine nucleotide exchange factor 37", "aln": "----------------------------MADFETDEASSKSESPEQEGQGSEDKSLLHQRLAIRELIDTEVSYLHTLRLCTSDIRGHLQQLPPG--DLDILFSNIDDIIQVSSRFLHGLQETACKEEKQ--AHLIGNLFLEFQEELEQVYKVYCANYDQALLLVKAYQKEPELQKEIQGIIEAAVPQAGPSGLSFLLVIPLQRITKYPLLLQKILENTPADASAHPVLQRATSALQDVNSNINEYKMRKEVALKYTKVEQLSLRERLARINTHTLSKKTTRLSQLLKQEAGLVPRTEDKEFDDLEERFQWVSLCVTELKSNVAAYMDNLEAFLCFRPHERNLDIPGG-AAEQYCSLARDLQLQAFLQFKQRLTGLVWQPLCSLARALVGPQNLIKKRLDKLLDFERVEEKLLDVGSVTYEEEAARHTYQALNSLIVAELPQFNHLVMQWLGQILRTFVVLQRDLADQVLRRAESSMALLPHRHVSEPDFQKLLEDTLGQSSSQLRHFRESFEKVLPPSTSQPLLPGSEHQMQSLLTRYGPGKIYQVTSNINGTGTLDLTLPRGQIVALLQNKDTKGNNSRWLVDTGGHRGYVPAGKLQLYHPINPSEKEPRRQ----TGMPEDYWLPTPEPTQPSVPTVPTMSQVVAVYPFVARSTHELSLQAG-------QPVTILEAQDK-----KGNPEWSLVEANGQR----GYVPSNFLARTPSPTPRGWNLPS--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A1IGU4-1", "uniprot_id": "ARH37_MOUSE", "id": "A1IGU4-1", "name": "Rho guanine nucleotide exchange factor 37", "aln": "----------------------------MADFGADEASSKSESPEQEDQGSEDRSLLHQRLAIRELIDTEVSYLHTLRLCASDIRSHLQQLPPG--DLDILFSNIDDIIQVSSRFLRGLQETACREEEQ--AHLIGNLFLEFQEEFEQVYKVYCANYDQALLLVKAYQKEPELQKEIQGIIEAAMPQAGPSGLSFFLVIPLQRITKYPLLLQKILENTPADASAHPALQRATSALQDVNGNINEYKMRKEVALKYTKVEQLSLRERLARINTHTLSKKTTRLSQMLKQEAGLVSRTEDKEFDDLEERFQWVSLCVKELRNNVVDFMGNLEVFLSFRPHERSLDIPGG-PAEQYCSLARDLQLHAFLQFKQRLRSLVWQPLCSLARALAGPQNLIKKRLDKLLDFDRVEEKLLDVGSVTWEEEAARHEYQALNSLLVAELPQFNQLVMQWLGQILCTFVVLQRDLADQVLRRAESTMALLPHHHVSEPDFQKLLEHTLGQSSSQLRLFQESFEKVLPPSTTQPLLPGSEHQMQALLTRYGPEKLYQVSSNINGTGTLDLTLLRGQIVALLQNKDTKGNNSRWLVDTGGHRGYVPAGKLQLYHPIIPSEKELRGQ----TGTHEDSWLPAPEPTQLSVPTVPTMSQVVAVYPFVARSTHELSLQAG-------QPVTILEAQDK-----KGNPEWSLVEANGQR----GYVPSNFLARTPSPTPWGWNLPS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1IGU5-1", "uniprot_id": "ARH37_HUMAN", "id": "A1IGU5-1", "name": "Rho guanine nucleotide exchange factor 37", "aln": "----------------------------MAKHGADEPSSRSGSPDREGRASEDRSLLHQRLAVRELIDTEVSYLHMLQLCASDIRSRLQQLPQG--DLDVLFSNIDDIIKVNSRFLHDLQETASKEEEQ--VQLVGNIFLEFQEELEQVYKVYCASYDQALLLVDTYRKEPELQRHIQGIVEAVVPQAGSSGLSFLLVIPLQRITRYPLLLQKILENTVPDASAYPVLQRAVSALQDVNTNINEYKMRKEVASKYTKVEQLTLRERLARINTHTLSKKTTRLSQLLKQEAGLIPRTEDKEFDDLEERFQWVSLCVTELKNNVAAYLDNLQAFLYFRPHEYNLDIPEG-PAVQYCNLARDLHLEAFLKFKQRLEGLVWQPLCSLAKALLGPQNLIKKRLDKLLDFERVEEKLLEVGSVTYQEEAARHTYQALNSLLVAELPQFNQLVMQWLGQIMCTFVTLQRDLAKQVLQRAEGSMAQLPHHHVPEPAFRKLVEDALGRTSNQLRSFQETFEKVQPPPTTQPLLPGSERQVQALLSRYGPGKLYQVTSNISGTGTLDLTLPRGQIVAILQNKDTKGNSGRWLVDTGGHRGYVPAGKLQLYH-VVPSAEELRRQ----AGLNKDPRCLTPEPSPALVPSIPTMNQVIAAYPFVARSSHEVSLQAG-------QPVTILEAQDK-----KGNPEWSLVEVNGQR----GYVPSGFLARARSPVLWGWSLPS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58H7J0-1", "uniprot_id": "A0AC58H7J0_DANRE", "id": "A0AC58H7J0-1", "name": "", "aln": "MANSLKANITLTVDEETEGAKEMDNALEELAEEEEDEEERKARVAAEEAAARERAAQRQLMAIEEMVHTEKNYLKHLQICTVTINSNLQKLQPPPPNLENMFQHIDEVMEVSSRLLSLLDQAQMQHSDPKYLETLCDSFLSLSQDIEMAYKEYLANYNNITALENSYKQKEALWMEMVRIIKSSAPDVNASTLSFFLVMPVQRIARYPLLFQTIQKHTDPQHPAYPELEHTAHTAIQINCRINEYKRFREVADKYKKTENLTIKDKLNRLSGHSIAKKTARFSQYIKHETGMVPKLKDEEFDALAGFFFVLERGVSELHDNLLTYLHHLQRFLSCRPEEADLDLEGEKTALFSKEITVALRQWIYPSYEKRLKTLVFKPLSSLRELMAGPRNLIRKRQDKLLDYEPIEEK----SNLTFEEQAIANTYKTMNTLLLNELPQFNGKALQLMWAALEAFSVLQRDLATDMEQLATSFTHQLPHSYLEAGDFWKWAETSVLEGSWRMESLCRSVQDELNAPIVQALNTVSKKRLMYLNANHGSEKIYQLTGPVVGTRDLDLTLNKGELVAVVCEMDTRGDRRRWLVDAGGPRGYVPASKLARYHQLTIDPPQSPHLNVTPTGPGPRRHSYTPGAQPHLTTITTPCFQVYAGYDFTARSAHELSLRAGSLCGSLFRRFWLLQMEGSGVSQITSNRVLALLAVSGQEPWGNAVAQTQFYPFPMSLECEGVRIKIFP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: ..:. * .:.::: :* :*:.*::.** .**: *::*: *...**:* :*: :*.:**::::*.**:* *::: :... . : : **.:.:::* .** * *.*:: * .:*::: * .: *::: *:...* ***:**:*:***::****:*.* ::* .: .*:* *:::. : ::* .***** :*** **.*.*:*:::::* *:. *:::***:*:** :*:*:*::.: :*:*** * * :. *.**:.*: :: :*: ** **.* .**: .* .:: *: : .:::** **::**.** . : **:***:** *****:: :*** ..:*::*:* : *:::*:*:: ****** .:* : : :* .****** :: : * . *** :: * * * :: . * ::. : .:.:. .. *.* . *:::: * :.:*. *:**::. : ** ***** :*::**:: : **:*: *****:** ******.** ** : . : :* :* . .. .. ** * * *.***:**:**:** : . :*: :.. ..* :*: ..**. . . : * . . * * : ", "identical_positions": 215, "similar_positions": 250, "identity": "29.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100519-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UN79-1", "uniprot_id": "SOX13_HUMAN", "id": "Q9UN79-1", "name": "Transcription factor SOX-13", "aln": "-------------------------------MSMRSPISAQLALDGVGTMVNCTIKSEEKKEP---CHEAPQGSATAAEPQPGDPARASQDSADPQAPAQGNFRGSWDCSSPEGNGSPEPKRPGVSEAASGSQEKLDFNRNLKEVVPAIEKLLSSDWKERFLGRNSMEAKDVKGTQESLAEKELQLLVMIHQLSTLRDQLLTAHSEQKNMAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQQVNMPYVMIPAFPPSHQPLPVTPDSQLALPIQPIPCKPVEYPLQLLHSPPAPVVKRPGAMATHHPLQEPSQPLNLTAKPKAPELPNTSSSPSLKMSSCVPRPPSHGGPTRDLQSSPP--SLPLGFLGEGDAVTKAIQDARQLLHSHSGALDGSPNTPFRKDLISLDSSPAKERLEDGCVHPLEEAMLSCDMDGSRHFPESRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTCIVEGKRLRVGEYKALMRTRRQDARQSYVIPPQAGQVQMSSSDVLYPRAAG----MPLAQPLVEHYVPRSLDPNMPVIVNTCSLREEGEGTDDRHSVADGEMYRYSEDEDSEGEEKSDGELVVLTD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q04891-1", "uniprot_id": "SOX13_MOUSE", "id": "Q04891-1", "name": "Transcription factor SOX-13", "aln": "-------------------------------MSMQSPVSVQLAPDSASTMVNCTIKSEEKKEP---CHEAPQGAAPAVETQPGDPALASQDATNAKAPPQ-------DCASPESSGSPEPKRPAASEAASGSQERLDFNRNLQEVVPAIEKLLSSDWKERFLGRSNVEAKDVKGTQESLAEKELQLLVMIHQLSALRDQLLTAHSEQKNMAAMLFEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQQVNMPYVMIPAFPPSHQPLPVTPDSQLALPIQPIPCKPVEYPLQLLHSPPAPVVKRSG-VAAHHPLQEPPQPLNLTAKPKVPELPNTSSSPSLKMNSCGPRPASHGAPTRDLQSSPP--SLPLGFLGEGDAVTKAIQDARQLLHSHSGALENSPNTPFRKDLISLDSSPAKERLEESCVHPLEEAMLSCDMDGSRHFSESRNSSHIKRPMNAFMVWAKDERRKILQAFPDMHNSSISKILGSRWKSMTNQEKQPYYEEQARLSRQHLEKYPDYKYKPRPKRTCVVEGRRLRVGEYKALMRTRRQGARQSYTIPPQAGQAQVSS-DILFPRAAG----LPLARPLVEHYDPQGLDPNMPVIINTCSLREEGEGTDDRHSVADGEMYRYSEDEDSEGDEKSDEELVVLTD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58GQI6-1", "uniprot_id": "A0AC58GQI6_DANRE", "id": "A0AC58GQI6-1", "name": "", "aln": "MSCFSRLAHWQVERFLKDELKIMSTDQILLRMCEPSPPALHPHAKGNVTMVGVGIKLEDDESGGRIVNRESQQSSPLSDWSARLPSDRDDSEKSANVHAQS------PLERSPSKDLLLSHSPASQDGGGRAHDKIESKPNVNEVMPTIEKLLNTDWKEKFLGKGLQGNVNLKGTPESLAEKELQLLLMINQLSGLREQLLGAHSEQRNMAALLLEKQQQQMELARQQQEQIAKQQQQLIQQQHKINLLQQQIQQVNMPYVMIPAFHPNAQPLPVTSEAQMGLPLQPIPCKPVEYPMQLLPNPHSTPIKRSSGTVYR---QDTSQPLNLTAKPKTP------SPQALELAHLQS-----GYRHRDLPQSPPRSALSLSFLGEGDVVTQAIHDAQQLLRGGQGSTGRERDNNTRLEASRDRMDDGHSRTNEDHHSSDSEGQMAISGVGSFGESRTPSSGHIKRPMNAFMVWAKDERRRILQAFPDMHNSSISKILGSRWKSMSNQEKQPYYEEQARLSRQHLERYPDYKYKPRPKRTCIVEGRRLRVGEYKAMMKSRRQEQRVSYPPSQSEQQLPYPPSEGQYPTTPVSMSTLPLHPALLEHYLPRGLEP------------PQGRVSETRESARP--RQPYSEGEESDAGERSEGELVVLTD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. ** : : .. ***. ** *:.:. :. .* ::. : .. *: .:. ..:. .* . ... .: *. .:... :::::: : *::**:*:*****.:****:***:. ::*** ***********:**:*** **:*** *****:****:*:*************************************************** *. ******.::*:.**:***********:*** .* :. :**.. . : *:..**********.* *. :*:: . * *** .*** :*.*.******.**:**:**:***:. .*: . :. * : . .:.* ::. . .*. :: . ** ..: .*.******************:************************:********************:**************:***:*********:*::*** * ** . . * .. : :* :. :** .*:*** *:.*:* :*. :: *.*. ***.*:*:. *:*: *******", "identical_positions": 309, "similar_positions": 157, "identity": "46.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100519-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5QD04-1", "uniprot_id": "TAAR9_MOUSE", "id": "Q5QD04-1", "name": "Trace amine-associated receptor 9", "aln": "MTSDFSPEPPMELCYENVNGSCIKSSYAPWPRAILYGVLGLGALLAVFGNLLVIIAILHFKQLHTPTNFLVASLACADFLVGVTVMPFSTVRSVESCWYFGESYCKFHTCFDTSFCFASLFHLCCISIDRYIAVTDPLTYPTKFTVSVSGLCIALSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNW-VLLCFLLFFLPTVVMVFLYGRIFLVAKYQARKIEGTANQAQASSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYIIDAVIDAYMNFITPAYVYEILVWCVYYNSAMNPLIYAFFYPWFRKAIKLIVSGKVFRADSSTTNLFSEEAGAG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RI9-1", "uniprot_id": "TAAR9_HUMAN", "id": "Q96RI9-1", "name": "Trace amine-associated receptor 9", "aln": "MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNW-VLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5QD24-1", "uniprot_id": "TAAR3_RAT", "id": "Q5QD24-1", "name": "Trace amine-associated receptor 3", "aln": "MDLIYIPED-LSSCPKFGNKSCPPTNRSFRVRLIMYLLMTGAMVITIFGNLVIIISISHFKQLHSPTNFLILSMATTDFLLGFVIMPYSMVRSVESCWYFGDSFCKFHASFDMMLSLTSIFHLCSIAIDRFYAVCAPLHYTTTMTASMIKRLLFFCWAAPALFSFGLVLSEANVSGMQSYEILIACFNFCALTFNKFWGTILFTTCFFTPGSIMVGIYGKIFIVSRRHARALGNMPENTKGAGRNLSK---KKDRKAAKTLGIVMGVFLACWLPCFLAVLIDPYLDYSTPIIVLDLLVWLGYFNSTCNPLIHGFFYPWFRKALEHIVSGKIFRSNSDTANLFPEAH---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M6Z1I0-1", "uniprot_id": "A0A8M6Z1I0_DANRE", "id": "A0A8M6Z1I0-1", "name": "", "aln": "-MAYETEDQETQYCFPDINSSCVKGRHSSHGYIIIYLFVSLLSVWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLIIGLFVIPIQAIKLIETCWYFGDTFCGLYLFLIFELLSASLSNLVLIAVDRYVAVCHPLLYPQKITITKTLMSICLSWVCYSAYNTALIINNRYS---ETSHRTDECYGRCFIVMSFSWLVADLVMSFIFPCLIMITLYLMIFYVVHQQVKVMNSLMKGGKCVTEGSVKR--KSESKAALTLGIIVTIYLLCYIPYYICSLVVN------SSTAIHVMSWTVYVNSGMNPLVYALFYPWFKKTAKIIFTLKIFQPASSLINIFTELDM--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * ** : *:* .: : : * **:::*:* ***:**:***::: *:* *:::*. ::* . :: :*:*****:::* :: : : :*: :* *::**: ** ** *. .:* : : :.* :. .:. . : * . * :. * . *: * *: :* ** * : :.: : . . : .. : * : *** **** : :* .::* : :: . . .:: * * ** ***::.:** ** *: : *.: *:::. *. *:*.* ", "identical_positions": 81, "similar_positions": 102, "identity": "23.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100525-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P12075-1", "uniprot_id": "COX5B_RAT", "id": "P12075-1", "name": "Cytochrome c oxidase subunit 5B, mitochondrial", "aln": "--------------------------MASRLLRGVGALAAQALRAHGPRGVAATRSMASGGGVPTDEEQATGLEREIMIAAQRG-LDPYNMLPPKA-ASGTKEDPNLVPSVSNKRIVGCICE-EDNCTVIWFWLHQGESQRCPNCGTHYKLVPYQMVH-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19536-1", "uniprot_id": "COX5B_MOUSE", "id": "P19536-1", "name": "Cytochrome c oxidase subunit 5B, mitochondrial", "aln": "--------------------------MASRLLRGVGALAAQALRRT-ARGAAVTRSMASGGGVPTDEEQATGLEREIMIAAQKG-LDPYNMLPPKA-ASGTKEDPNLVPSISNKRIVGCICE-EDNCTVIWFWLHKGESQRCPNCGTHYKLVPHQMAH-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P10606-1", "uniprot_id": "COX5B_HUMAN", "id": "P10606-1", "name": "Cytochrome c oxidase subunit 5B, mitochondrial", "aln": "--------------------------MASRLLRGAGTLAAQALRARGPSGAAAMRSMASGGGVPTDEEQATGLEREIMLAAKKG-LDPYNVLAPKG-ASGTREDPNLVPSISNKRIVGCICE-EDNTSVVWFWLHKGEAQRCPRCGAHYKLVPQQLAH-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A3X0-1", "uniprot_id": "A0AB13A3X0_DANRE", "id": "A0AB13A3X0-1", "name": "Cytochrome c oxidase subunit 5B, mitochondrial", "aln": "--------------------------MAARLLLRS-ATRAVVLRHRTLPAPAVARALASGG-IPTDDEQATGLERIVMEASKKG-LDPYNILKPKE-YAGSKQDPHIVPSISTKRIVGCVCE-EDNTAVVWFWLHQGEAQRCPSCGAYYKLVPHELPH-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMB9-1", "uniprot_id": "Q9VMB9_DROME", "id": "Q9VMB9-1", "name": "", "aln": "----------------------------MASICGRMALR----AAARQN--VAYTPVRFCKMMNDPLEHATGIEKRELLLKAAGNDNPFDM-KVFKRGAGTKENPNLIPSAFDARIVGCICE-EDQTYVQWMWLQKGN-QKRCECGHWFKLVEKAAV------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMB8-1", "uniprot_id": "Q9VMB8_DROME", "id": "Q9VMB8-1", "name": "", "aln": "MSSYISRLLKAQSASKRLISNLTQRDGKLSSLLRRLGLQWQGSAAAPQQRPISTTQVQKSALIADD-QLVTGIQKREMLLAKQGCEDPWGFSKVIRRGSGRENDPTVVPSAFDARLVGCLCL-DDR-LPKWMWIEKDEGPKRCECGHYFILKNVPPV------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P04037-1", "uniprot_id": "COX4_YEAST", "id": "P04037-1", "name": "Cytochrome c oxidase subunit 4, mitochondrial", "aln": "-------MLSLRQSIRFFKPATRTLCSSRYLLQQKPVVKTAQNLAEVNGPETLIGPGAKEGTVPTDLDQETGLARLELLGKLEG-IDVFDTKPLDSSRKGTMKDPIIIESYDDYRYVGCTGSPAGSHTIMWLKPTVNEVARCWECGSVYKLNPVGVPNDDHHH", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : **: : : * : :. * ::* :: * * *** . *: .: : ** : * ", "identical_positions": 14, "similar_positions": 19, "identity": "8.59%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100525-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3U108-1", "uniprot_id": "ARI5A_MOUSE", "id": "Q3U108-1", "name": "AT-rich interactive domain-containing protein 5A", "aln": "---------------------------MAAPPAKGNTEQSEEGDLPQLPVSPKPDDEQSRSQSPTQLQDSPEAGGEQEEEQ------AFLVSLYKFMKERHTPIERVPHLGFKQINLWKIYKAVEKLGAYELVTGRRLWKNVYDELGGSPGSTSAATCTRRHYERLVLPYVRHLKGEDDKPLPPTKPRKQYKMAKELRGDDGTTEKLKKAKD--SEERRVEQTTPGKTKSDATGQTQLPCQ--GSSRDSTEQLGPVSGPSPPLTGASSCPEAYKRLLSSFYCKGAHGIMSPLAKKKLLAQVSKAEALQCQEEGCRHGAR---SPNKDIQDSPQNLRGPAENSEHQLTPREGLQAPGGSTRMEAQVGPCPTAPMFSGCFHAYPTEVLKPVSQHP----RDFFSGLKDRVLLGPPGKEEGPTTKESHLVWGGDANHPSAFHKGST-RKRSFYPKPKACWVSPMAKVPTERPGAPSPHPSSPGLGSKRGLEEEGFAHGGKKLRAVSPFLKEVDSKETGGKPAAPGLAVSCLLGPTPGPTPPEAYRGTMLRCPLNFTGSADPLKGQASLPFSPLVIPAFPAHLLATTGSSPMAASLMHFPPTPYDAVLRNRLGPASSAWHMPPVTTYAAPHFFHLNTKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03989-1", "uniprot_id": "ARI5A_HUMAN", "id": "Q03989-1", "name": "AT-rich interactive domain-containing protein 5A", "aln": "---------------------------MAAP-VKGNRKQSTEGDALDPPASPKPAGKQNGIQNPISLEDSPEAGGEREEEQEREEEQAFLVSLYKFMKERHTPIERVPHLGFKQINLWKIYKAVEKLGAYELVTGRRLWKNVYDELGGSPGSTSAATCTRRHYERLVLPYVRHLKGEDDKPLPTSKPRKQYKMAKENRGDDGATERPKKAK----EERRMDQMMPGKTKADAADPAPLPSQ--EPPRNSTEQQGLASGSSVSFVGASGCPEAYKRLLSSFYCKGTHGIMSPLAKKKLLAQVSKVEALQCQEEGCRHGAEPQASPAVHLPESPQSPKGLTENSRHRLTPQEGLQAPGGSLREEAQAGPCPAAPIFKGCFYTHPTEVLKPVSQHP----RDFFSRLKDGVLLGPPGKE-GLSVKEPQLVWGGDANRPSAFHKGGS-RKGILYPKPKACWVSPMAKVPAESPTLPPTFPSSPGLGSKRSLEEEGAAHSGKRLRAVSPFLKEADAKKCGAKPAGSGL-VSCLLGPALGPVPPEAYRGTMLHCPLNFTGTPGPLKGQAALPFSPLVIPAFPAHFLATAGPSPMAAGLMHFPPTSFDSALRHRLCPASSAWHAPPVTTYAAPHFFHLNTKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G603-1", "uniprot_id": "A0AC58G603_DANRE", "id": "A0AC58G603-1", "name": "", "aln": "MPTDPADLLAVRRSCYPLRHRDAGHFRVLDPRGEVDAAEGELEDCEKKNQELNSPNQTNGEMESLTSTNSSEDNSRSDQSES--EERTFITNLYCFMKERNTPIERIPHLGFKQINLWKIYKAVETLGGYDAVTARRQWKNVYDELGGSPGSTSAATCTRRHYERLVLPFERQLRGEEDKPLPPSKPRKQYKRSPENRGSKPESKKKRKMERDESEEKMLSDHHCDRGRCSHHSPWLISSDRLDSEHTSTAPVLGMSSRENPLLQTSSPPEVISPLEKKKRLAQASLTIPASEDGGELERPSVIHISHSSQSNTRGRHS---SDGSPVPVSSPSGSLSRSPSPYSVSSEDCIAVTTQKSPAKEPENKTATRLPALSTSKAVSTGVCKPLSCYPNTKELANYPRLHYREFLQAGATE---KTQRSLLAWTSDDKSRLASHRLPLPAYTKPYWVPHASSFSKVLPRDPCRPMSSLQPSFKPHMSSYHQHLLKRPDEAYLKKMPVSSPIRITDRKEKAKTALPKPLPTQQYLFHPHG-GLTVPYQPALERLRGDLT-----VEQLKALPLQPVLFPTHLSIPPAQSHSMHCPPVGTHFP-GSYEAALPSYNYPMP-IWHAP--AGYNMPSLQPY----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : : :. * . . :. .: . .. :*.* ... ::.: :*:..** *****:*****:******************.**.*: **.** *******************************: *:*:**:*****.:******* : * **.. ::: :* : **: :.: .: :.. . :..: . : ** *. . .: :*. **. . * .. : :.. . * : * . :..:.. * * : *. . . * : ::..: : .. . : . .: . : .* * **:* :* :. *: :* . ..* ..:.. *.* .* : * *: * *:*. .* : . * . . .* :.* : : .. : .**. :: .* *: . .. * .. * . * . .*: :: : ::* :: :**:.*:::*:. : * : . .. *** .:::.* * . ** * : * * : ", "identical_positions": 153, "similar_positions": 183, "identity": "24.09%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100603-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99727-1", "uniprot_id": "TIMP4_HUMAN", "id": "Q99727-1", "name": "Metalloproteinase inhibitor 4", "aln": "-------MPGSPRPAPSWVLLLRLLALLRPPGLGEACSCAPAHPQQHICHSALVIRAKISSEKVVP-ASADPADTEKMLRYEIKQIKMFKGFEKVKDVQYIYTPFDSSLCGVKLEANSQKQYLLTGQVLSDGKVFIHLCNYIEPWEDLSLVQRESLNHHYHLNCGCQITTCYTVPCTISAPNECLWTDWLLERKLY-GYQAQHYVCMKHVDGTCSWYRG--HLPLRKEFVDIVQP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JHB3-1", "uniprot_id": "TIMP4_MOUSE", "id": "Q9JHB3-1", "name": "Metalloproteinase inhibitor 4", "aln": "-------MPWSPLAALSWALVLRLLALLWPPGRGEACSCAPAHPQQHFCHSALVIRAKISSEKVVP-ASKDPADTQKLIRYEIKQIKMFKGFEKAKDIQYVYTPFDSSLCGVKLETNSHKQYLLTGQILSDGKVFIHLCNYIEPWEDLSLVQRESLNHHYHQNCGCQITTCYAVPCTISAPNECLWTDWLLERKLY-GYQAQHYVCMKHVDGICSWYRG--HLHLRKEYVDIIQP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B7U7-1", "uniprot_id": "A0ACD6B7U7_DANRE", "id": "A0ACD6B7U7-1", "name": "Metalloproteinase inhibitor 4", "aln": "MMMMMMMMKMCTRECVTAGLLFFMCVCLN-QQMLEACSCASAHPQQLFCSADAVLRAEITGEKIRRREDINPMYGLGKIQYEVQVIKVFKGSDRIKDLQHVYTHEMSSMCGIRLNRG---QYLLSGSMMSEG-FFVTLCDFVEHWDRLSLTQKKNLKYRYQMGCNCTISICTEQPCHPKVKNECILTDWSSLWPFEDGEPVHEYACIRHSDGSCSWHEGGTSVPSEKNTTDISEG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .. . : *:: : . * ******.***** :* : *:**:*:.**: . :* ::**:: **:*** :: **:*::** **:**::*: . ****:*.::*:* .*: **:::* *: ***.*::.*:::*: .*.* *: * ** .. ***: *** : * .:.*.*::* ** ***:.* : .*: .** : ", "identical_positions": 82, "similar_positions": 72, "identity": "34.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100603-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P57748-1", "uniprot_id": "MMP20_MOUSE", "id": "P57748-1", "name": "Matrix metalloproteinase-20", "aln": "MKVLPASGLAV-LVTALKFATADPNLLAATPRTFRSNYHLAQAYLDKYYTKKGGPQAGEMVARESNPMIRRIKELQIFFGLKVTGKLDQNTMNVIKKPRCGVPDVANYRLFPGEPKWKKNILTYRISKYTPSMSPTEVDKAIQMALHAWSTAVPLNFVRINSGEADIMISFETGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTN--GFNLFTVAAHEFGHALGLGHSTDPSALMYPTYKYQNPYRFHLPKDDVKGIQALYGPRKIFPGKPTMPHIPPHKPSIPDLCDSSSSFDAVTMLGKELLFFKDRIFWRRQVHLPTG--IRPSTITSSFPQLMSNVDAAYEVAERGIAFFFKGPHYWVTRGFHMQGPPR-TIYDFGFPRHVQRIDAAVYLKEPQKTLFFVGEEYYSYDERKKKMEKDYPKNTEEEFSGVSGHIDAAVELNGYIYFFSGRKTFKYDTEKEDVVSVVKSSSWIGC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60882-1", "uniprot_id": "MMP20_HUMAN", "id": "O60882-1", "name": "Matrix metalloproteinase-20", "aln": "MKVLPASGLAVFLIMALKFSTAAPSLVAASPRTWRNNYRLAQAYLDKYYTNKEGHQIGEMVARGSNSMIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTN--GFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKDDVKGIQALYGPRKVFLGKPTLPHAPHHKPSIPDLCDSSSSFDAVTMLGKELLLFKDRIFWRRQVHLRTG--IRPSTITSSFPQLMSNVDAAYEVAERGTAYFFKGPHYWITRGFQMQGPPR-TIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGVNGQIDAAVELNGYIYFFSGPKTYKYDTEKEDVVSVVKSSSWIGC-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P50280-1", "uniprot_id": "MMP7_RAT", "id": "P50280-1", "name": "Matrilysin", "aln": "---MAAMRLTLFRIVCLLPGCLALPLSQEAGEVTALQWEQAQNYLRKFYLHDS-------KTKKATSAVDKLREMQKFFGLPETGKLSPRVMEIMQKPRCGVPDVAEFSLMPNSPKWHSRTVTYRIVSYTTDLPRFLVDQIVKRALRMWSMQIPLNFKRVSWGTADIIIGFARGDHGDNFPFDGPGNTLGHAFAPGPGLGGDAHFDKDEYWTDGEDS-GVNFLFVATHELGHSLGLGHSSVPSSVMYPTYQGDHSEDFSLTKDDIAGIQKLYGKRNKL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q10738-1", "uniprot_id": "MMP7_MOUSE", "id": "Q10738-1", "name": "Matrilysin", "aln": "------MQLTLFCFVCLLPGHLALPLSQEAGDVSAHQWEQAQNYLRKFYPHDS-------KTKKVNSLVDNLKEMQKFFGLPMTGKLSPYIMEIMQKPRCGVPDVAEYSLMPNSPKWHSRIVTYRIVSYTSDLPRIVVDQIVKKALRMWSMQIPLNFKRVSWGTADIIIGFARRDHGDSFPFDGPGNTLGHAFAPGPGLGGDAHFDKDEYWTDGEDA-GVNFLFAATHEFGHSLGLSHSSVPGTVMYPTYQRDYSEDFSLTKDDIAGIQKLYGKRNTL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M6YV12-1", "uniprot_id": "A0A8M6YV12_DANRE", "id": "A0A8M6YV12-1", "name": "", "aln": "---MSWLWPWILLFWMLKMDSVRTSRVALQS-CTQEDFQHAEEYLRHFYHLKMR----VYNKRRAERMKDKIRAMQHFFDLKETAFLDHKTLNGMKEARCGVPDVENFSFYPGRPKWKSNIITYRIARFTPDLRPEEVENSLHLALKIWSDAAPLKFVQIKEGRADITFSFNSKAHGDFFPFDGPGGVLAHAFEPGEGLGGDVHFDDDEIWTVGRGRPGYNLFTVAAHELGHSLGLSHSKDPTALMYPKYKFINAATYKLPRDDTLGIQALYGKKTRQ-----------QELVIPNKCDVIS-FDAVTVLEKEIIFFKNSYMWMRTNWRSYWNRLKEGPQSVFLPSIPSPIDAAYDIPSQRVAYVFTGPKYWVVQKLESKSYYYGSIYEFGFPEIVRQIDAAVHVSEGGKTYFFTGDYYFSYDEKRNVMDRGFPRKINTGWPGIVGKVDAAFELNGRVHLFCRSKSFIFSHQKR-LLHTMNTNAWLGCS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * ::. *: ** ::* . : .:: :* **.* *. *. :: :::.******* :: : *. ***:.. :**** :*..: *:: :. **: ** **.* ::. * *** :.* *** :***** ..*.*** ** *****.***. * ** * . * *:: .*:**:**:***.**. * ::***.*: . : *.:** *** *** :. ", "identical_positions": 92, "similar_positions": 71, "identity": "18.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100603-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P57748-1", "uniprot_id": "MMP20_MOUSE", "id": "P57748-1", "name": "Matrix metalloproteinase-20", "aln": "MKVLP--ASGLAV--LVTALKFATADPNLLAATPRTFRSNYHLAQAYLDKYYTKKGGPQAGEMVARESNPMIRRIKELQIFFGLKVTGKLDQNTMNVIKKPRCGVPDVANYRLFPGEPKWKKNILTYRISKYTPSMSPTEVDKAIQMALHAWSTAVPLNFVRINSGEADIMISFETGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLGHSTDPSALMYPTYKYQNPYRFHLPKDDVKGIQALYGPR--KIFPG------KPTMPHIP--PHKPSIPDLCDSSSSFDAVTMLGKELLFFKDRIFWRRQVHLPTGIRPSTITSSFPQLMSNVDAAYEVAERGIAFFFKGPHYWVTRGFHMQGPPRTIYDFGFPRHVQRIDAAVYLKEPQKTLFFVGEEYYSYDERKKKMEKDYPKNTEEEFSGVSGHIDAAVELNGYIYFFSGRKTFKYDTEKEDVVSVVKSSSWIGC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60882-1", "uniprot_id": "MMP20_HUMAN", "id": "O60882-1", "name": "Matrix metalloproteinase-20", "aln": "MKVLP--ASGLAVF-LIMALKFSTAAPSLVAASPRTWRNNYRLAQAYLDKYYTNKEGHQIGEMVARGSNSMIRKIKELQAFFGLQVTGKLDQTTMNVIKKPRCGVPDVANYRLFPGEPKWKKNTLTYRISKYTPSMSSVEVDKAVEMALQAWSSAVPLSFVRINSGEADIMISFENGDHGDSYPFDGPRGTLAHAFAPGEGLGGDTHFDNAEKWTMGTNGFNLFTVAAHEFGHALGLAHSTDPSALMYPTYKYKNPYGFHLPKDDVKGIQALYGPR--KVFLG------KPTLPHAP--HHKPSIPDLCDSSSSFDAVTMLGKELLLFKDRIFWRRQVHLRTGIRPSTITSSFPQLMSNVDAAYEVAERGTAYFFKGPHYWITRGFQMQGPPRTIYDFGFPRHVQQIDAAVYLREPQKTLFFVGDEYYSYDERKRKMEKDYPKNTEEEFSGVNGQIDAAVELNGYIYFFSGPKTYKYDTEKEDVVSVVKSSSWIGC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F3C3-1", "uniprot_id": "E7F3C3_DANRE", "id": "E7F3C3-1", "name": "", "aln": "MQVLLCLVCAFDLFGQHYSLPLPLGDDGMVHPT-KPAQNDLSLATKYLQQFYSFQADSAGRKRRSRPS--FSSKLKNMQGFFGLNGTGTLNADTLAVMRTPRCGVSDVEDYSHRRGN-RWKKNIITYGVGRYTNDLPVNAVDDLISSALDVWAKASPLTFLRSYSHQADIMVEFVGKEHGDFFPFDGPDGTLAHAFGPGEGIGGDVHFDEAEVWTAGYNGFNLYVVAAHEFGHALGLKHSQLPESVMYPTYKRRKTHN-LLSSEDIININTLYGPRDKRPYPSSRFSWSNPSTPWYSGSYFPVSFKDTCNPHLKFDAVTTVGDAIFFFRDNYMWIKHNDQKD-IKEGPISNFMPKIDCHIDAAYWVPQRSTAYLFNGTTFWTVKGSQVKGRAKNISSLGFPSWVQQVDAAVHIHKTVHTLFFTQHQYWRYNEHNKNMTDSIPRNISDDFPEISGPISAAIYKDGYLHFFIGSDVYKYDIKQKEIIGTDKTTSWLGC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:** ...: : :* :. . .:: .: :. :.: ** **:::*: : . : :* * : ::*::* ****: **.*: *: *::.*****.** :* *: :**** :** :.:** .:. **. :. **..*:.* **.*:* * :****:.* :*** :***** *******.****:***.***:** ** * *****:.************ ** *.::****** ::.: *..:*: .*::***** : : . :*: * . . *: * *:. .***** :*. :::*:*. :* :: . *: ..*:. :*:: .::**** *.:*. *::*:*. :* .:* :::* .:.* .:*** **::****::::. :****. .:*: *:*::::* .. *:* .::*. :.* *.**: :**::** * ..:*** ::::::.. *::**:**", "identical_positions": 186, "similar_positions": 181, "identity": "37.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100609-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BIW1-1", "uniprot_id": "PRUN1_MOUSE", "id": "Q8BIW1-1", "name": "Exopolyphosphatase PRUNE1", "aln": "MEDYLQDCRAALQ----DSRPLHVVLGNEACDLDSMVSALALAFYLTKTSEAEDIFIPVLNIKRSELPLRGDNVFFLQEVKIPEPALIFRDEIDLLALHQAGQLTLILVDHHILPKSDAALEEAVAEVLDHRPIEQKYCPPCHVSVELVGSCATLVTERILQGAPETLDRQTAALLHGTIILDCVNMDTNIGKATPKDSKYVEELEALFPDLPKRKDIFDSLQKAKFDVSGLTTEQMLRKDQKTVYRQGTKVAISAIYMDLKAFLQRTDLFTDLSSFCHDHSYDALVAMTIFFNTQNEPVRQLAIFCPHEALRMTICGILERSTSPPLKLTPIPSTSPNLQAYHQGNTQVSRKKLLPVLQEALSAYLDSAKMASGQSEVAVGMSREQVDKDLDKASNSLISGLSQD---EEDPPLPPTPMNSLVDECPLDQGLPKFSAEAVFEKCSQISLSQSARACTSNK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86TP1-1", "uniprot_id": "PRUN1_HUMAN", "id": "Q86TP1-1", "name": "Exopolyphosphatase PRUNE1", "aln": "MEDYLQGCRAALQ----ESRPLHVVLGNEACDLDSTVSALALAFYLAKTTEAEEVFVPVLNIKRSELPLRGDIVFFLQKVHIPESILIFRDEIDLHALYQAGQLTLILVDHHILSKSDTALEEAVAEVLDHRPIEPKHCPPCHVSVELVGSCATLVTERILQGAPEILDRQTAALLHGTIILDCVNMDLKIGKATPKDSKYVEKLEALFPDLPKRNDIFDSLQKAKFDVSGLTTEQMLRKDQKTIYRQGVKVAISAIYMDLEAFLQRSNLLADLHAFCQAHSYDVLVAMTIFFNTHNEPVRQLAIFCPHVALQTTICEVLERSHSPPLKLTPASSTHPNLHAYLQGNTQVSRKKLLPLLQEALSAYFDSMKIPSGQPETAD-VSREQVDKELDRASNSLISGLSQD---EEDPPLPPTPMNSLVDECPLDQGLPKLSAEAVFEKCSQISLSQSTTASLSKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F6P6-1", "uniprot_id": "E7F6P6_DANRE", "id": "E7F6P6-1", "name": "", "aln": "MEAYLRSCRDVLKSCSRNSPGLHVVMGNEACDMDSMVSALTFAYFLSKSLDCKRIPVPVLNIPRAEFPLRSDSIFLLRESGLSQDYLLFRDEVDLHGLHKNKQLTLTLVDHNVLPSADSELEDAVVEVIDHHLLQ-RPSSSCPITVEPVGSCTTLVTERIAQKSPAVLDQQVAQLLYGTIILDCVNMAPEAGKVTPKDSQYAIFLEQRFPKLPPRGALFQSLQNAKFDVSGLSTEQMLLKDMKAASGGDLRLAVSVIYMTLEDFLQRSGLQQDLCEFCHSHNYNLLLAMTISFKDSKEPFRQLAVYSSSTVYREEMSKALEKAKNPSLELKPLSSPYPDVKAFIQGNTLASRKKVMPIITDFLK-----------EKERREAQCMNMEDLDLDDDSNQDQSDCLEDAGIEDDTRVPPTPMNSLVEGCPLDNGLPKISPEALVEKVSKMASMEDTSPEEQ--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **:.** .*: :* ****:******:** ****::*::*:*: :.: : :***** *:*:***.* :*:*:: :.: *:****:** .*:: **** ****::*..:*: **:**.**:**: :: : ...* ::** ****:******* * :* **:*.* **:********** : **.*****:*. ** **.** * :*:***:********:***** ** *: . ::*:*.*** *: ****:.* ** **: *.*: *:**** *: :**.****::.. . : :. **:: .*.*:*.* .*. *:::*: **** .****::*:: : *. : * . : * :** **. *. :* *:*. :*********: ****:****:*.**:.** *::: :.: . . ", "identical_positions": 214, "similar_positions": 132, "identity": "46.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100609-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIY0-1", "uniprot_id": "PKHO1_MOUSE", "id": "Q9JIY0-1", "name": "Pleckstrin homology domain-containing family O member 1", "aln": "-MKKSGSGKRGPPDGNHQSAAPEKVGWVRKFCGKGIFREIWKNRYVVLKGDQLYVSEKEVKDEKNSQEVFDLSDYEKCEELRKSKSRSKKNHSKFTLARCRQPGTTAPNLIFLAVSPEEKESWINALSSAITRAKNRILDEVTVEEDSYLAHPTRDRAKIQHSRRPPTRGHLMAVASTSTSDGMLTLDLIQEEDPSPEEPASCAESFRVDLDKSVAQLAGSRRRADSDRIQPS---SQRASSLSRPWEKPDKGAP--YTPQALKKFPSTEKSRCASLEEILSQRDTAPARPLHLQAEESLPPVPAQPGQLSRIQDLVARKLEKTQELLAEVQGLGDGKRKAKDPPQSPPDSESEQLLLETERLLGEASSNWSQAKRVLQEVRELRDLYRQMDLQTPDSHLR----QTSQHSQYRKSLM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53GL0-1", "uniprot_id": "PKHO1_HUMAN", "id": "Q53GL0-1", "name": "Pleckstrin homology domain-containing family O member 1", "aln": "MMKKNNSAKRGPQDGNQQPAPPEKVGWVRKFCGKGIFREIWKNRYVVLKGDQLYISEKEVKDEKNIQEVFDLSDYEKCEELRKSKSRSKKNHSKFTLAHSKQPGNTAPNLIFLAVSPEEKESWINALNSAITRAKNRILDEVTVEEDSYLAHPTRDRAKIQHSRRPPTRGHLMAVASTSTSDGMLTLDLIQEEDPSPEEPTSCAESFRVDLDKSVAQLAGSRRRADSDRIQPS---ADRASSLSRPWEKTDKGAT--YTPQAPKKLTPTEKGRCASLEEILSQRDAASARTLQLRAEEPPTPALPNPGQLSRIQDLVARKLEETQELLAEVQGLGDGKRKAKDPPRSPPDSESEQLLLETERLLGEASSNWSQAKRVLQEVRELRDLYRQMDLQTPDSHLR----QTTPHSQYRKSLM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QIX7-1", "uniprot_id": "E9QIX7_DANRE", "id": "E9QIX7-1", "name": "", "aln": "-MKKNSSSKRGPQDANQQPVQPDKTGWIRKFCGKGIFREIWKNRFVILKGDQLLISEKEVKDEKKIQEVVDLTDYEKSEELRKAKSRSKKNHSKFTLLRSRQPGNTVPNLVFLAVSPEEKESWINALNAAITRAKNRILDEVTVEEDSLLAHPTRDRAKIPHTRRLPTRGHLMAVASTTNSDGMLTLDLIQEEDVPAEQGQASGEDT-VDKASSQRSPDSQPSNTDTSKLSCSNEIAGKSQSLPRKSESAFDWSENHRTPQLRKKPTTSEKNRCASMDEILTH---CEARALPHCS----TSAPVQP--ISQLQDLITLKLERTQELLTEVRAQGKGKGSPAGKSSSPEGKRKE-----AERLLEEAASTWGQARDVLEEVKELRALYKQLDSSATISPTQNGKLNSPQQANHRKSMM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***..*.**** *.*:*.. *:*.**:****************:*:****** :*********: ***.**:****.*****:************* :.:***.*.***:****************.:******************* *********** *:** ************:.************** ..*: :..*. ** .* . .. .:*:.::. * : ::.**.* *.. . : *** ** ..:**.****::***:: . **.* : ... :* :*::***:: ***.*****:**:. *.** .. . . ** ....* :**** **:*.*.**: **:**:*** **:*:* .:. * : ::. ::::***:*", "identical_positions": 231, "similar_positions": 110, "identity": "55.26%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100609-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7Z3K3-1", "uniprot_id": "POGZ_HUMAN", "id": "Q7Z3K3-1", "name": "Pogo transposable element with ZNF domain", "aln": "MADTDLFMECEEEELEPWQKISDVIEDSVVEDYNSVDKTTTVSVSQQPVSAPVPIAAHASVAGHLSTSTTVSSSGAQNSDSTKKTLVTLIANNNAGNPLVQQGGQPLILTQNPAPGLGTMVTQPVLRPVQVMQNANHVTSSPVASQPIFITTQGFPVRNVRPVQNAMNQVGIVLNVQQGQTVRPITLVPAPGTQFVKPTVGVPQVFSQMTPVRPGSTMPVRPTTNTFTTVIPATLTIRSTVPQSQSQQTKSTPSTSTTPTATQPTSLGQLAVQSPGQSNQTTNPKLAPSFPSPPAVSIASFVTVKRPGVTGENSNEVAKLVNTLNTIPSLGQSPGPVVVSNNSSAHGSQRTSGPESSMKVTSSIPVFDLQDGGRKICPRCNAQFRVTEALRGHMCYCCPEMVEYQKKGKSLDSEPSVPSAAKPPSPEKTAPVASTPSSTPIPALSPPTKVPEPNENVGDAVQTKLIMLVDDFYYG-RDGGKVAQLTNFPKVATSFRCPHCTKRLKNNIRFMNHMKHHVELDQQNGEVDGHTICQHCYRQFSTPFQLQCHLENVHSPYESTTKCKICEWAFESEPLFLQHMKDTHKPGEMPYVCQVCQYRSSLYSEVDVHFRMIHEDTRHLLCPYCLKVFKNGNAFQQHYMRHQKRNVYHCNKCRLQFLFAKDKIEHKLQHHKTFRKPKQLEGLKPGTKVTIRASRGQPRTVPVSSNDTPPSALQEAAPLTSSMDPLPVFLYPPVQRS----------IQKRAVRKMSVMGRQTCLECSFEIPDFPNHFPTYVHCSLCRYSTCCSRAYANHMINNHVPRKSPKYLALFKNSVSGIKLACTSCTFVTSVGDAMAKHLVFNPSHR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSSILPRGLTWIAHSRHGQTRDRVHDRNVKNMYPPPSFPTNKAATVKSAGATPAEPEELLT----------------------------------------------------------------------------PLAPALPSPASTATPPPTPTHPQALALPPLAT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EGAECLNVDDQDEGSPVTQEPELASGGGGSGG-------------------------------------VGKKEQLSVKKLRVVLFALCCNTEQAAEHFRNPQRRIRRWLRRFQASQGENLEGKYLSFEAEEKLAEWVLTQREQQLPVNEETLFQKATKIG--RSLEGGFKISYEWAVRFMLRHHLTPHARRAVAHTLPKDVAENAGLFIDFVQRQIHNQDLPLSMIVAIDEISLFLDTEVLSSDD--RKENALQTVGTGEPWCDVVLAILADGTVLPTLVFYRGQMDQPANMPDSILLEAKESGYSDDEIMELWSTRVWQKHTACQRSK-GMLVMDCHRTHLSEEVLAMLSASSTLPAVVPAGCSSKIQPLDVCIKRTVKNFLHKKWKEQAREMADTACDSDVLLQLVLVWLGEVLGVIGDCPELVQRSFLVASVLPGPDGNINSP--------------------------------TRNADMQEELIASLEEQLKLSGEHSE---SSTPRPRSSPEETIEPESLHQLFEGESETESFYGFEEADLDLMEI--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BZH4-1", "uniprot_id": "POGZ_MOUSE", "id": "Q8BZH4-1", "name": "Pogo transposable element with ZNF domain", "aln": "MADTDLFMECEEEELEPWQKISDVIEDSVVEDYNSVDKTTSVSVSQQPVSAPVPIAAHASVAGHLSTSTTVSNSGAQNSDSTKKTLVTLIANNNAGNTLVQQGGQPLILTQNPAPGLGTMVTQPVLRPVQVMQNANHVTSSPVASQPIFITTQGFPVRNVRPVQNAMNQVGIVLNVQQGQTVRPITLVPAPGTQFVKPTVGVPQVFSQMTPVRPGSTMPVRPTTNTFTTVIPATLTIRSTVPQSQSQQTKSTPSTSTTPTATQPTSLGQLAGQPPGQSNQTSNPKLAPSFPSPPAVSIASFVTVKRPGVTGENSNEVAKLVNTLNTVPSLGQSPGPVVVSNNSSA---QRTSGPESSVKVTSSIPVFDLQDGGRKICPRCNAQFRVTEALRGHMCYCCPEMVEYQKKGKSLDAEPSVPSAAKPSSPEKTAPVTSTPSSTPIPALSPPTKVPEPNENAGDAVQTKLIMLVDDFYYG-RDGGKAAQLTSFPKVATSFRCPHCTKRLKNNIRFMNHMKHHVELDQQNGEVDGHTICQHCYRQFSTPFQLQCHLENVHSPYESTTKCKICEWAFESEPLFLQHMKDTHKPGEMPYVCQVCQYRSSLYSEVDVHFRMIHEDTRHLLCPYCLKVFKNGNAFQQHYMRHQKRNVYHCNKCRLQFLFAKDKIEHKLQHHKTFRKPKQLEGLKPGTKVTIRASRGQPRTVPVSSNDAPSGTLQEAAALTS-TDPLPVFLYPPVQRN----------IQKRAVRKMSVMGRQTCLECSFEIPDFPNHFPTYVHCSLCRYSTCCSRAYANHMINNHVPRKSPKYLALFKNSVSGIKLACTSCTFATSVGDAMAKHLVFNPSHR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSNILPRGLSWMSHLRPGQASERVFDWSMKNTYLPPPLVPNKAATVKPVGVTPAEPQELAG----------------------------------------------------------------------------PVLQALPSPASTATPPATPTHPQPSALPPSAT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EGTECLNVSEQEEGSPVTQDPEPASGGGGGSG-------------------------------------VGKKEQLSVKKLRVVLFALCCNTEQAAEHFRNPQRRIRRWLRRFQASQGENLEGKYLSFEAEEKLAEWVLIQREQQLPVNEETLFQKATKIG--RSLEGGFKISYEWAVRFMLRHHLTPHARRAVAHTLPKHVAENAGLFIEFVQRQIHNQDLPLSMIVAIDEISLFLDTEVLSSDD--RKENALQTVGTGEPWCDVVLAILADGTVLPTLVFFRGQANRFANVPDSILLEAKDSGYSDDEIMELWSTRVWKKHTACQHSK-SMLVMDCHRTHLSEEVLALLSASSTLPAVVPAGCSSKIQPLDVCIKRTVKNFLHKKWKEQAREMADAACDSDVLLQLVLVWLGEVLGVIGDSPELVQRSFLVASVLPGPDGNVNSP--------------------------------TRNADMQEELIASLEEQLKLNGEQSEEHSASAPRPRSSPEETVEPESLHQLFEGESETESFYGFEEADLDLMEI--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1R5F8-1", "uniprot_id": "F1R5F8_DANRE", "id": "F1R5F8-1", "name": "", "aln": "-MDSDLFMECEEEELEPWQQQ------SMDEPAGNAESSTPSVTSTPAPVVDVPAPPKTMVIPSLTSVVNAANTVPLITNTITQRAVVPTEIPKAVQ------GQPVILAPG-GGGLGTVALSQVLLPGTSIANVTNS-------QPIYFTTQGLPVQNIQPGQ---GPMSLVLNVQQGQTVRPITLLQAPGTQIFKPAIGATQIITQPAQIRAGAPVVNRAQTPSTFSTVQIPATLTFRTTNAVTPTAASSLPIVSSTTITQPT--------------RTTTKIVTIKQGNGPLDMQNLMNLVKSVNLPGGAQAQTFVVMSNQNTKNGPVVSSAVPIIS---------------QNVIQTIPLPNATSSTTTTHLCPRCGAQFRMIEALRGHMCFCCPDLVHMTETSSTPTAVKPPATPPKSASVVPSAKVDSPPSKT-------------------GDSHPRLVMLVDDFYYGTFEGNRVYVPMDNSKEPLSFRCLTCSKKLKNNIRLMNHMRYHVELDQQNGEMDNHTSCQHCFRRFPTPFRLQCHLESVHTSIESSTKCKICEWSFENEPVFLQHMKNSHKPGEMPYVCQVCEYRSSFYSDVFNHFRTWHEDTRHLLCQYCLKVFKHSTSYQQHYVRHQKSTVYHCNKCRLQFLFTKDKVEHKINHHRTFRKPRELDGLQPGTKVTIRAYVG--KKTPGQSASKASTNIQKNSISSSQSTTLSGDQQSEQQQSGKKQVSKMFQFLSKFQEQRAQLGRHKCVECTFDIPDFVNHYPTYVHCSLCFYSTCCSRAYANHMINNHVPGRAPK--PSKKGPPSVVKLTCAGCEYSTPHGNLMAKHLIKFPDHSYCLFMRKECLETDIEFCHVEEEVEGPQGDEASDVGTQPDWLSLKQWNVPKEEGTVPEFMERCGPRHIMTRNHDVLDYFQVLFPDALFELIVCETNAYATYCCSSGQGDTSWHPVSVQEIKGFFGLSILMGLQNLVEPDSYWTWEQHQGRYGSRTWELVYRTMSVNRFKQISTYIRMSSMLVENDSQSADKLSFFQPMLSILEKSMQEAYSPNKCLTIDQAFLPSHDKGTAQEKSKNSQPRIWLLCDSKSGFCHKLLVSTRQEKHKDLGKSVVPHLTEGLEGKHHNIFLSSSLASVQLMKDLFDSGIYCSSSVLPQSAVLPKEFWDEPPLENPGNFKQYEFPPLLATRWKDTKELVCLSTNANAGHEDVVWRRSPTKMGELYTIERPQAFKLLQDNMRGVDICNQLLTCNQLGGLDLDTNWRRLFWFFVNLSIINSFIVLRETRKDNPPVWLPGGHFSQAVFRKRLGYQLAKCAERHTLQNQIHNSMIEQQTVKKESQEVQEEVRHRLGKITRRARRCKVCNLKNMRHESMYGCTACHANLCKRSRCFWEFHGFPTNYQGSAKVGFVDSKRDGTEPGLKHKTEMLERGQAKSSVDISNVSQGATAGQDEDVDQEMAPLEDEDTETDTDTVESSEEVPLRTVASEKEKRSLTKPTQPVRNREESLTIHQRRILLLALCAGIQKAAKEMDTKPQLIKTWIQDKEDQLNECCS--SICGEAVDRLVQWVLTQREQQRPINEARLFEKASELQSQTNETSSFRISYEWAVNFMMQHKLGLDTCFTVQRELPSAMEENCRCFKELVHGQVKTNNVPQCVIGVMDQLSVFVDINMLNEKNKVRRDTAIQFTGSGKPFVKIYLAMLANGTMLPAALFTSHTTSTLSSTPDTVLIMAKEEGYKATEELEIWATKVWKQHLDSQNEKEALLVLDSHHCLTSESIISTVSSTKTFLPTIPAGCTCRHQPLEMCVRPVLQRLFLSRWAQQPKESVQ----PEDLMQLLVSWLDKAMSCFSSRPEFIQHSFCLAHLLPDQETHTDLPGTSVELLNILSEATLGPEVVDLESADEEEPMDTHSVDNVTEKIDLTEEQEDTENELNDDKAKNTEQQKETNDECLEIASESTDFSHSSPEHETPSHNSEPDHLSESGLDANTDQTDSANR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:***************: *: * ...:.:*. .* . . ** ..:: * *:: ...:.: . ::: .: *. :* : ***:**: . . ****:. . ** * : *..: ***::****:**:*::* * . :.:***************: *****:.**::*..*:::* : :*.*:.: *. * : :.: . *: ..:: : : *: . ::.* **** :*:. :: . . * : ** .:.* . :. ::.. ** . *.. ::* ..: * .:* . ::****.****: ********:***::*. :...: : . .:..*..* :* * *.**.* . :.:*:********* :*.:. . .* . **** *:*:******:****::**********:*.** ****:*:*.***:******.**:. **:********:**.**:******::*************:****:**:* *** ********* *******:..::****:**** .*************:***:***::**:*****::*:**:********* * :..* .* . .. :*: : :* .*. . *:. : .: .: : :**:.*:**:*:**** **:********* ******************* ::** . *.. * :**:*:.* : *. *: *****: *.* ** :: .. : *. : : .::: * * . . * : . . .*: :. * .**. .* .* : : :** : :. ..:::.: .:*:.. *: : . . . .::*.*:::: *::*:***.. ::**:.: . : *: *:: : . .* . :. ** ::*.:*** ***** *:** **:**::: . ..*:*******.**::*:* .: :* : **. : **. * ::*: *::.:::* .:* .:*::*:*:* ::*...: *::.*:* .*:*:*: .: **:**:**:**: :* . :. **::*: **:.**. * :*:*:*:**::* .*..* .:**:*.*: **.::: :*::.*: ..:****:.: ***::*:: .::.:: .:* :*.:* .: .: *:**:: **.:.:. :.. **::*:** :* :**. : : : * *:..* * * *** . ..* .: .: : :.: :* :* * *. .* .. ..:. .* * ", "identical_positions": 505, "similar_positions": 477, "identity": "25.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100609-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JTK1-1", "uniprot_id": "A0A0G2JTK1_RAT", "id": "A0A0G2JTK1-1", "name": "non-specific serine/threonine protein kinase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MQCLAAALKDETNMSGGGEQ------ADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWEKAGTDALLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPPILPGRPPEGLGPGPHLVPHPGGPEAEVWEETDVNRNKLRINIGKTPCVEEEQSRGVGVPSSPVRAPPDSPTTPVRSLRYRRVNSPESERLSTAADGRAELQERRSRMDLPGSPSRQACSSQPAQMLSVDTGHADRQASGRMDVSASVEQEALSNAFR-SVPLAEEEDFDSKEWVIIDKETELKDFP--PGAEPSTSGTTDEEPEELRPLPEEGEERRRLGTEPTVRPRGRGMQTLAEEDPRQMLPQPAPPQLSQADGRSETSQPPTPGSPSHSPLHSGPRPRRRESDPTGPQRQVFSVAPPFEVNGLPRAVPLGLPYQDFKRDLSDYRERARLLN--RVRRVGFSHMLLTTPQVPLAPFQPQANGKEGEEEEEEDEEEEEEEEEEDEEDEEEEDEEDEDEEEEE----AGALGEVLGPRSGSSSEGS----ERSQEGAPSTLLADD-QKEARGRASMADGDLEPEEGSKTLVLVSPGDMKKSP-VTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSILKSEPK---PSGPGAGVGVGLVAPGAG-VTAVTSPFTKVERTFVHIAEKSHLNVMSSGGQAPRPEELSTGGELGLEMLSEVGAAEEGAPQPLENGMALVGPDGTEMESCALSGPPGETPS--EVVTDSLPDG---PALADEPAPASPQEPITK---KGTIISPSRHAMPGSRPRSRIPVLLSEEDTGSEPSGSLSAKERWSKRARPQQDLARLVMEKRQGRLLLRLASGASS--SSSEEQRRASETLSGTGSEEDTPASEPAAALPRKAGRAATTR---SRIPRPISV--SMPAEGQQLPGRPHGAASATDSAITSRLQLQKPPGL-ATAADHRPKQPASRASGPGRAQV-SKPAAPRSPGLPTST--ARHSSGSPRSQSLSRKESSSPSHQAR--PGFPPSRGVLQVRSQSE--ASPGGPKK-GPKGKQLQTLRAATKGRP------------AVSEGRPGNR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PCN3-1", "uniprot_id": "TTBK1_MOUSE", "id": "Q6PCN3-1", "name": "Tau-tubulin kinase 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MQCLAAALKDETNMSGGGEQ------ADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWEKAGTDALLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPPILPGRPPEGLGPGPHLVPHPGGPEAEVWEETDVNRNKLRINIGKTPCVEEEQSRGVGVPSSPVRAPPDSPTTPVRSLCYRRVNSPESERLSTAADGRVELQERRSRMDLPGSPSRQACSSQPAQMLSVDTGHADRQASGRMDVSASVEQEALSNAFR-SVPLAEEEDFDSKEWVIIDKETELKDFP--PGAEPSTSGTTDEEPEELRPLPEEGEERRRLGTEPTVRPRGRGMHTLTEEDPRQMLPQPAPPQLSQADGRSETSQPPTPGSPSHSPLHSGPRPRRRESDPTGPQRQVFSVAPPFEVNGLPRAVPLALPYQDFKRDLSDYRERARLLN--RVRRVGFSHMLLTAPQVPLAPFQPQANGKEGEEEEEEEEEEEEEEEEEEEEEEEEEEEE---EEEEE----AGALGEVLGPRSGSSSEGSERSTERSQEGAPSTLLADD-QKEARGRASMADGDLEPEEGSKTLVLVSPGDMKKSP-VTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSILKSEPK---PSGPGAGGGVGLVAPGAG-VTAVTSPFTKVERTFVHIAEKSHLNVMSSGGQASRPEELSTGGELGLEVLSEGGIAEEGAPAPLENGMALAGLDGTEMESCALSGPPGETPS--EVVTDSLPNG---PALADGPAPASQQEPVTK---KGTTISPSRHAMPGSRPRSRIPVLLSEEDTGSEPSGSLSAKERWSKRARPQQDLARLVMEKRQGRLLLRLASGASS--SSSEEQRRASETLSGTGSEEDTPASEPTTALPRKAVRAATTR---SRIPRPISV--SMPVEGQQLPGRPHGAASATDLAITSRLQLQKPSGL-APAADLRPKQSASRGPGPGRAQV-SKPAAPRSPGLPAST--ARHPSGSPRSQSLSRKESSSPSHQAR--PGVPPSRGVLQVRSQPE--ASPVAPKK-GPKGKQLQTQRAATKGRA------------VVSEGRPGAR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TCY1-1", "uniprot_id": "TTBK1_HUMAN", "id": "Q5TCY1-1", "name": "Tau-tubulin kinase 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MQCLAAALKDETNMSGGGEQ------ADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWEKAGTDALLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPPILPGRPSEGLGPSPHLVPHPGGPEAEVWEETDVNRNKLRINIGKSPCVEEEQSRGMGVPSSPVRAPPDSPTTPVRSLRYRRVNSPESERLST-ADGRVELPERRSRMDLPGSPSRQACSSQPAQMLSVDTGHADRQASGRMDVSASVEQEALSNAFR-SVPLAEEEDFDSKEWVIIDKETELKDFP--PGAEPSTSGTTDEEPEELRPLPEEGEERRRLGAEPTVRPRGRSMQALAEEDLQHLPPQPLPPQLSQGDGRSETSQPPTPGSPSHSPLHSGPRPRRRESDPTGPQRQVFSVAPPFEVNGLPRAVPLSLPYQDFKRDLSDYRERARLLN--RVRRVGFSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRSQEGAPSTLLADD-QKESRGRASMADGDLEPEEGSKTLVLVSPGDMKKSP-VTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSVLKSEPK---PPGPGAGLGAGTVTTGVGGVAVTSSPFTKVERTFVHIAEKTHLNVMSSGGQALRSEEFSAGGELGLELASDGGAVEEGARAPLENGLALSGLNGAEIEGSALSGAPRETPS--EMATNSLPNG---PALADGPAPVSPLEPSPE---KVATISPRRHAMPGSRPRSRIPVLLSEEDTGSEPSGSLSAKERWSKRARPQQDLARLVMEKRQGRLLLRLASGASS--SSSEEQRRASETLSGTGSEEDTPASEPAAALPRKSGRAAATR---SRIPRPIGLRMPMPVAAQQPASRSHGAAPALDTAITSRLQLQTPPGS-ATAADLRPKQPPGRGLGPGRAQAGARPPAPRSPRLPASTSAARNASASPRSQSLSRRESPSPSHQAR--PGVPPPRGVPPARAQPDGTPSPGGSKK-GPRGK-LQAQRATTKGRA------------GGAEGRAGAR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BDS7-1", "uniprot_id": "A0A8M3BDS7_DANRE", "id": "A0A8M3BDS7-1", "name": "non-specific serine/threonine protein kinase", "aln": "---------------------------------------------------------------------------------------------------------------------MINGSFKLGAARVLSGLQCLAPALQDNANMNGTAEQ------QDILPPHCMVKDRWKVLKKIGGGGFGEIYEALDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCKFIGCGRNDKFNYVVMQLQGRNLADLRRSQPRGTFTMSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTFRKCYMLDFGLARQYTNTNGEVRPPRTVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFAAGQLPWRKIKDKEQVGQIKERYDHRMLLKHMPSEFNVFLEHVLALDYYTKPDYQLLMSVFENSMKERIITENEPYDWEKSGTETIISATTPTAAQQNTRPTAAMVGVINVTPMPGDLPRENTDDVVQDEHLSDQENAPPIPSGRPVDGS-------QMP--TDADGWEETDFNRNKLRINLGKG-GQEEDGSRGV-CPVSPQRGGLDSPGMQVHSIRYRRVNSPESDRMSA-ADGRDGYGQR-SRMDILGSPSRHVYSSQPAQMLSVDG------CRGRNEASASVDQEAHSNAFIRSVPLAEEEDFDSKEWVIIDKEMELRDFHHLPGAEPTTSGTTDEEPEELRPLEEGDDRRRHRGNDPSVRTK----TSHGERTTRGMLPLTEEETSRRSGKGQSTSMESPAQSPCHS-LPSG-RPRRRDADNNGPQRQAPTPSE-----------PLLSPTDYRTKSPSSEKEMFHILPKLQAKRADFLTVMLTG-----SLHQRRAFTATPPETQDEGPRDDDVTKSE------------------------------------SSSGASEKSTERSQDGAPSTLVADDPQKESKEPGSVADVDPDQEDVSNTLVLFSPGDTKKSPNAIIRAEVDQGVGSFDAPQNENQGQSEVQKQEDIKQAERPIDGRQADVTGFDPFIQSSKPVVTISTTPVASASIASPLFSKVEQTFVHIAETTHLNVMSSSSGQVLEVLQEVEGKLQSKLTKDKPEPGGGAACVQSEVISQILTEESQVPNVLDGSLPNESTVKQENPTDPLCVQSMEPIIQDSTIDSNQDEKPKEEIQEGSTVPDIVSKPPRPRSRSRIPILVPEEEPGSEKS--LSTKERMRRRVM-QQDLARQVVERHRQGRWIRLNSRTSSSLSSGDEPKRPSETLSTTGSEEDVLESDDSLNKLKKEAEEKHQTGWHSRIPRPVTPIRKPSTKLVVAPPLSQPEAAKLEQKASNGPKVQSQSGSSAPAFHARSKSTLSHSTMPSGSNCMPLSCIPAASRRSLSTANCTFSSARIASPSPHRLHLRTAVIESRKQPFALRTTVELPLKSRTTTCSNPAKDTKPSPNKATNTTVRNRTKASTQSKNTVPAKKEKSTSNNAAAAR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IMC6-1", "uniprot_id": "ASATR_DROME", "id": "Q8IMC6-1", "name": "Tau-tubulin kinase homolog Asator", "aln": "MFWHLLCVPNDENASAPDDGNQSCQPSSKQDQYLSPNRNCQKNLLRLYPPPPSKPPPLVGAILQTRLLHQISPSAIADADADLNAVGELLYPNVLQRSATLPAKHNRLGVRSRVTFKVPSSNLPAQDSYSHQPRNQVAVAAKDGILVDVKAKESVKMTSEDLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTTGTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWEKVDSTAIGNISATGNPSIPIKSDYMHGNITQMTVAASNASGTEYIRKRAEIETAHITATDPLNIKEKVDKN------------CNATSLAQPAKGSGEPMVQHGNAANNQNITSKGLQQQSTLTNSQVAIANIQSAPSMIERED-VQYTKLEEGAPTKFITMKPNGECDNVDIAAKCIFEQKHVEAN--------DDIVGRASLSG-VEQHYKSQIKKHNSPEIANKQIQRTGTVTNDKTSEVNRSTEEQKSTFGRLRVLTAPPMSVHDLPSGGGHSHQVSDLS------------GKQDPYAATSNAAPIGINSSSTKFGSQHGQIFGLAAMPPINRRSATSTNLRPSSSASQRIN-----------------SGSTIGGAVGNGSNTARSSVAG-----DHSVTQFALIDDENVSALQQVTKGGALTLASQWKSQFDDSEDTTDN---------------------------------------------EWNREHQLQPNLEQLIKLDISLPLNEAKPFPQHGVAGTGKLINPPGEAKGRP----------KRYTLNITGIENYEALRISIPNCWSEPAMGNVLRKGLEP---PAVQQAAFDDTVYRMDIARNVCVRETYSEIT----HLARPSTSSVLRN----RLPSPFKKDSALQLNSTNDSLDKSRHRNSLPNVSVNDIFDDLQMKLNLDLGSAIQENNC---CISGRLEIR---------VIPKDTSHPDDS--VYYDAMGAVKNTPTANEGHDHSDQAVNNCDEMEATSAVIAFPNKSISKIMSPPGRD--ATEERTGASLCSLYSAGVN--KLKLNGNTAPRTQFKKGSTDGFGENESEFDFPLLNPSKIPVR--------------------------------------------QSKCASWAGADFISASKPLESAEVPQEIPYHPQSDTTYSVIDSIPVRKTTYSIALECPPNISDLTPGLSYFYCN---IVVPLRLFSILLTES----------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* * :* :. .:: *:* . :**:****::************. **:***:********:*******************:***:*******::**********:***:***:****:*::******* ***::**:****************::**** . *: ************. .*:** ** .***********:***:*:******************. *************** **:*:**:****:**::: **:*: :* * :*** :::.:**..**.* : *.:.:**** .: :: . ::. .. : .: ::* ..: : . :. : *: . : :* :. . .: :: *: :: *:*: : .. . . .* : : ::. * : : .. * . .:: ..: .: ** . *. *:*. *: . * ::::: . * ** *:. : . * .:: * . . . :: . . :. . . .. :. .. . : . . ....:: . . .. : .. . * : * : : ::. : : .:: .. : : : : . *. : .. :: .**: * * :: :: .:. :. * : . . :::: *:*. : .*: . . . * : .: . : : . .. *. :. * . . . : . . :.: : : : . * :: :: : . . *.: * * . . : . ...* .** :. .: *. . * * .... . * . . . : . .. . . . . . .. :.. ", "identical_positions": 260, "similar_positions": 304, "identity": "17.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100609-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5TCY1-1", "uniprot_id": "TTBK1_HUMAN", "id": "Q5TCY1-1", "name": "Tau-tubulin kinase 1", "aln": "MQCLAAALKDETNMSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWEKAGTDALLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPP-ILPGRPSEGLGPSPHLVPHPGGPEAEVWEETDVNRNKLRINIGKSPCVEEEQSRGMGVPSSPVRAPPDSPTTPVRSLRYRRVNSPESERLST-ADGRVELPERRSRMDLPGSPSRQACSSQPAQMLSVDTGHADRQASGRMDVSASVEQEALSNAFR-SVPLAEEEDFDSKEWVIIDKETELKDFPPGAEPSTSGTTDEEPEELRPLPEEGEERRRLG--AEPTVRPR-GRSMQALAEEDLQHLPPQPLPPQLSQGDGRSETSQPPTPGSPSHSPLHSGPR--PRRRESDPTGPQRQVFSVAPPFEVNGLPRAVPLSLPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTTPQVPLAPVQPQANGKEEEEEEEEDEEEEEEDEEEEEEEEEEEEEEEEEEEEEEEAAAAVALGEVLGPRSGSSSEGSERSTDRSQEGAPSTLLADDQKESRGRASMADGDLEPEEGSKTLVLVSPGDMKKSPVTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSVLKSEPKPPGPGAGLGAGTVTTGVGGVAVTSSPFTKVERTFVHIAEKTHLNVMSSGGQALRSEE-FSAG-GELGLELASDGG-------------AVEEGARAPLENGLALSG---------LNGAEIEGSALSGAPR--------------ETPSEMATNSLPNGPALADGPAPVSPLEPSPEKVATISPRRHAMPGSRP----RSRIPVLLSEEDTGSEPSGSLSAKERWSKRARPQQDLARLVMEKRQGRLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPAAALPRKSGRAAATRSRIPRPIGLRMPMPVAAQQPASRSHGAAPALDTAITSRLQLQT-PPGSATAADLRP-KQPPGRGLGPGRAQAGARPPAPRSPRLPASTSAARNASASPRSQSLSRRESPSPSHQARPGVP--PPRGVPPARAQPDGTPSPGGSKKGPRGK-LQAQRATTKGRAGGAEGRAGAR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PCN3-1", "uniprot_id": "TTBK1_MOUSE", "id": "Q6PCN3-1", "name": "Tau-tubulin kinase 1", "aln": "MQCLAAALKDETNMSGGGEQADILPANYVVKDRWKVLKKIGGGGFGEIYEAMDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNEKFNYVVMQLQGRNLADLRRSQPRGTFTLSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTYRKCYMLDFGLARQYTNTTGDVRPPRNVAGFRGTVRYASVNAHKNREMGRHDDLWSLFYMLVEFAVGQLPWRKIKDKEQVGMIKEKYEHRMLLKHMPSEFHLFLDHIASLDYFTKPDYQLIMSVFENSMKERGIAENEAFDWEKAGTDALLSTSTSTPPQQNTRQTAAMFGVVNVTPVPGDLLRENTEDVLQGEHLSDQENAPP-ILPGRPPEGLGPGPHLVPHPGGPEAEVWEETDVNRNKLRINIGKTPCVEEEQSRGVGVPSSPVRAPPDSPTTPVRSLCYRRVNSPESERLSTAADGRVELQERRSRMDLPGSPSRQACSSQPAQMLSVDTGHADRQASGRMDVSASVEQEALSNAFR-SVPLAEEEDFDSKEWVIIDKETELKDFPPGAEPSTSGTTDEEPEELRPLPEEGEERRRLG--TEPTVRPR-GRGMHTLTEEDPRQMLPQPAPPQLSQADGRSETSQPPTPGSPSHSPLHSGPR--PRRRESDPTGPQRQVFSVAPPFEVNGLPRAVPLALPYQDFKRDLSDYRERARLLNRVRRVGFSHMLLTAPQVPLAPFQPQANGKEGEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEEE-------AGALGEVLGPRSGSSSEGSERSTERSQEGAPSTLLADDQKEARGRASMADGDLEPEEGSKTLVLVSPGDMKKSPVTAELAPDPDLGTLAALTPQHERPQPTGSQLDVSEPGTLSSILKSEPKPSGPGAGGGVGLVAPGAG-VTAVTSPFTKVERTFVHIAEKSHLNVMSSGGQASRPEE-LSTG-GELGLEVLSEGG-------------IAEEGAPAPLENGMALAG---------LDGTEMESCALSGPPG--------------ETPSEVVTDSLPNGPALADGPAPASQQEPVTKKGTTISPSRHAMPGSRP----RSRIPVLLSEEDTGSEPSGSLSAKERWSKRARPQQDLARLVMEKRQGRLLLRLASGASSSSSEEQRRASETLSGTGSEEDTPASEPTTALPRKAVRAATTRSRIPRPISV--SMPVEGQQLPGRPHGAASATDLAITSRLQLQK-PSGLAPAADLRP-KQSASRGPGPGRAQV-SKPAAPRSPGLPAST--ARHPSGSPRSQSLSRKESSSPSHQARPGVP--PSRGVLQVRSQPE--ASPVAPKKGPKGKQLQTQRAATKGRAVVSEGRPGAR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PVD4-1", "uniprot_id": "A0A8M9PVD4_DANRE", "id": "A0A8M9PVD4-1", "name": "non-specific serine/threonine protein kinase", "aln": "MQCVGPGVHGDENMNGAGEQVDILPSNCLVKDRWKVLKKIGGGGFGEIYEAYDLLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKNHVCKFIGCGRNDKFNYVVMQLQGRNLADLRRSQPRGTFSMSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTCRKCYMLDFGLARQYTNTNGEVRPPRSVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFTVGQLPWRKIKDKEQVGQIKERYEHRMLLKHMPAEFHIFYDHVLDLDYFTKPDYQLLMSVFENSMKDRVITENEPYDWEKSGTDTALPTSTHTPPQQNTRQTAAIVGVVNVTPVPGELPRENTDDVLQDEHLSDQENAPPALIPSRPTE---------PAPAAPAGEAWDETDFNRNQLRISISKTQVAAEDGDEPAGGGRSVSPARGGEGDAQARPPRYRRVNSPESERLSG-AEDRGDGADKRSRLDMLGSPSRHVYSSQPAQMLSLEGGQGERLAGGRHDVSADGDQEAHSNAFIRSVPLAEEEDFDSREWVMIDKETELKDFLPGAEPTTSGTTDEEPEELRPLEDHEERRRRVHGGAEAVVRPKTQRGMMIVAEE---------------------EGAGP----SPGHSSCHTLPRSCPRRRESEPFGPDGPDIAVAE---------------PSPSFS------------QTRMKRVDFVSGVLMF----------------------------------------------------------DDLREEVVKTGGSGSDGSPRSSEGSPEGAASTLLAPAHR-----------DHDQEEGSRTLVLVSAG-------NGQVSPGDGQGTLAALTPQGERPVP-----EESEPGTLSSVIKSEPRP---IVMTTAAVITSGSS-----SPPFTKVERTFIHIAETSHLNVMTARHRPSGFDEPISVERDEMGEEKEDRSGQLVEIERNSKGIKVEREGDEKKKEESEAEKEKQEVENVIISSREEAETVFLAEQPVSIAIKENISIETKLDDEQDGVTTEKEQEQEESPSVSPEQNRDAEVEDEKDVSPPEVESPDRKPLPQRRSRIPVLMSEDETGSDKSSQTSQEQLQRTRKSRHQQLARLVLERKQTHMMR------SRSASSHSPTLSTTASEDEAHQSDDSAKGADGKIKSRIPRPVTPIRGSYDLLKCATLPQTQRSVSFIQYRTNSSINPKIQKSASLHTNIHQQPPKPQLRPSKTLPPLPPSSGPSHTQGSRTATRTVTRTSAPNATRSISTSPRSYGTSRTDSPSPQRIRRQLAANETQRQAQQPRPPVPSVSKSKPQDSTTPRKSKSHPSTSTKAKKDPLESKTKTR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:...::.: **.*.***.****:* :********************** ***********************************:***:*******:**************************::**************************************** *****************.*:*****.************:*****:******************:**************** ***:***********:***:* **: .***********:*********:* *:***.:****:***: *.*** ************:.**********:* ****:****.*********** ::*.**.* * *..* .*.*:***.***:***.*.*: . *: .. * * * .. : .*. ************* *:.* : ::***:*: *****:. *********:: *:.:* *.** ****. :*** **** ************:***:********** *****:*************** :. *.***: :*..***: *.* ::** * : * **.**. *: ** ******:* **: ::** * .*. .*::**.* :* * * : .**.*:** **:: * ***.***** :: * : ****:******.* ..:::*. . ********* *** * : ********::****:* . .. ::.* . :.*********:****.:*****:: :. :* :*. .*:* * . .* .** *:. * . * * *: * : .: .* . : : . :* . :. :. :** . *. :* *******:**::***: *.. * :: .* :*:*****:*::* ::: * *:*... * * * :.:. ::: : . :. ..* * . : .:* :. . : : .: : * . .*:. .. .:*** * . ..* ::. . .*.*: .::. :* * **** . ** :*.**.: * .. . * . *. ... .. . * . ::**.: *.:. :*", "identical_positions": 633, "similar_positions": 274, "identity": "46.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100616-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RYL4-1", "uniprot_id": "B2RYL4_RAT", "id": "B2RYL4-1", "name": "Armadillo repeat-containing protein 6", "aln": "-------------------------MASKRITQETFDAAVRENIEEFEMGAEEAIREAVEQFESQGVDLSNIVKTVPKVSLD-GLQEPTHDVLQALNDLQQALTGSQLQEVSAHLVRFCDQCKQQKASRYLAAQKGAYPILLAAWQLAATS---DQGLLLQALNALAVLTDGQPDLLDTQGLHLLVATLARN--AANTELTCCGIRCVRHVCLKHEQNRQGLVKAGVLPLLTAAITQHGQHADVVREACWALRVMTFDDDIRVPFGHAHEHAKMIVQENRGLKVLIEAARAFSDNPGVLSELCSTLSRLAVRNEFCQEVIDLGGLGILVTLLADCNDH--------QDLVKQVLSALRAIAGNDDVKDAIVRAGGTQSIVAAMTRHLASPQVCEQSCAALCVLALRKPENSRVIIEGGGALAALQAMKAHPQEAGVQ--ACMLIRNLVSRSQVFSKPILDLGAEELILQARAAHPDCEDVAKAALRDLGCRVELRELWTGKKGNLAP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BNU0-1", "uniprot_id": "ARMC6_MOUSE", "id": "Q8BNU0-1", "name": "Armadillo repeat-containing protein 6", "aln": "-------------------------MASKRITQETFDAAVRENIEEFEMGTEEAIREAVEQFESQGVDLSNIVKTIPKVSLD-GLQEPTHSVLQALNDLQESLTGSRLQEVSAHLVRFCDQCKQQKASRYLAAQKGAYPILLAAWQLAATS---NQGLLLQALNALAVLTDGQPDLLDAQGLHLLVATLAQN--AANTELTCCGIRCVRHVCLKHEQNRQDLVKAGVLPLLTAAITQHGQHADVVREACWALRVMTFDDDIRVPFGHAHEHAKMIVQENKGLKVLIEAARAFSDNPGVLSELCSTLSRLAVRNEFCQEVIDLGGLGILVTLLADCNDH--------QDLVKQVLSALRAIAGNDDVKDAIVRAGGTESIVAAMTRHLASPQVCEQSCAALCVLALRKPDNSRVIIEGGGALAALQAMKAHPQEAGVQKQACMLIRNLVSRSQVFSKPILDLGAEELILQARAAHPDCEDVAKAALRDLGCRVELRELWTGKKGDLAL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NXE6-1", "uniprot_id": "ARMC6_HUMAN", "id": "Q6NXE6-1", "name": "Armadillo repeat-containing protein 6", "aln": "MSERCCSRYSSGASIGCTPTSTQAKMVSKRIAQETFDAAVRENIEEFAMGPEEAVKEAVEQFESQGVDLSNIVKTAPKVSAD-GSQEPTHDILQMLSDLQESVASSRPQEVSAYLTRFCDQCKQDKACRFLAAQKGAYPIIFTAWKLATAG---DQGLLLQSLNALSVLTDGQPDLLDAQGLQLLVATLTQN--ADEADLTCSGIRCVRHACLKHEQNRQDLVKAGVLPLLTGAITHHGHHTDVVREACWALRVMTFDDDIRVPFGHAHNHAKMIVQENKGLKVLIEATKAFLDNPGILSELCGTLSRLAIRNEFCQEVVDLGGLSILVSLLADCNDHQMRDQSGVQELVKQVLSTLRAIAGNDDVKDAIVRAGGTESIVAAMTQHLTSPQVCEQSCAALCFLALRKPDNSRIIVEGGGAVAALQAMKAHPQKAGVQKQACMLIRNLVAHGQAFSKPILDLGAEALIMQARSAHRDCEDVAKAALRDLGCHVELRELWTGQRGNLAP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQJ2-1", "uniprot_id": "A0A8M3AQJ2_DANRE", "id": "A0A8M3AQJ2-1", "name": "", "aln": "-------------------------MAKRRITQDTFDSVVRENIDDFDMEESEALKEAIEQFESQGVDLSNIVKAVPKVSSEENAQDQTHEVLQALESLKSAVSSSS-TSVLDDLRLFTDQCNLGFAQRYLAAQKDAYPTILSCCQKSAG----DKEALSVALAALCALTDGQPDLLDEEGKLFLIRVLTEHQHQQDAGVVCLCVRTVRNCCLKHENNRQDLVKAGVLPLLAGSITRYLQHPEVVRDACVALRVMTFDDDVRVPFGHAHEHAKMIVLEQNGLKVMVEAAKAHPENTSVLSELCATLSRLAVRNEFCQDIVDLGGLKFMITLLADSLDC--------QELVKQVLSALKAIAGNDDVKDAIVNAGGAELIVMAMNRHMANAQVCEQGCAALCVLALRKPNNCKVIMESGGALAALQAMKTHPAEANMQKQSCMLLRNLVARSRDFTQPILEMGAEALISQALAAHRDCGDVGRAALRDLGCQVELRELWTGTKGSLSH-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7K486-1", "uniprot_id": "ARMC6_DROME", "id": "Q7K486-1", "name": "Armadillo repeat-containing protein 6 homolog", "aln": "--------------------------MAKVISQDTFDDVVKENVVEFSMTPSEAKEETIKQFEAQGINLANIIKDLS-VNPQTGQPVINETVDKIKEHIGQKLEETT--ELLEQLATLDAECKKSLAHRVLAGKNGAHDALITLLEETLSAESPNESVLKKSLEAINSLTHKQPDLFDAEAMAVVLKLLALK--VESEEVTLLTLQWLQKACIMHEMNRQNIMNTSALKLMKPLLGKG--KDRLVRELTAVFRFLVLDDDIRVEFGCAHEHARQIAG--EVLITLVELLPAYQD-PNVLADLLLTIGTLAVRQELCTAIDEAGGLKSVFEIMSSNLDEVR--------LNREALKLLRALAGQDSVKSHIVQQGVAPIIKQLLETHQSNENIVAAALACVTTLTLRVQEHSAAFFDTGIAEVIVEALRAHPKHKIVQRNGAWAIRNMVSRSRNQCETWISFGVEDLLNMAMKEHPSVEQDIKAALRDLGCSVHLREEWTGTAEKKIAA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:*:*** .*:**: :* * .** .*:::***:**::*:**:* . *. : . .. : : . : . : : .: * : :*: * * **.::.*: ::: : : :: * :* *: **. ****:* :. .:: *: : . :. :: ::: *: ** ***.::::..* *: : : : :**: .:*.:.:***:** ** **:**: *. . * .::* *. : ..:*::* *:. **:*:*:* : : *** :. :::. * * ::.*. *:*:**:*.**. **. * : * : * :. :: . *.: *:** ::. :.: * * . ::*:::** . :* .. :**:*::.: :. :.:*.* *: * * . : :******** *.*** *** . ", "identical_positions": 126, "similar_positions": 168, "identity": "24.8%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100618-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A4FU28-1", "uniprot_id": "CTGE9_HUMAN", "id": "A4FU28-1", "name": "cTAGE family member 9", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEPGATPQPYLGLVLEELGRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLWRSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEAT---------CEKLSRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELKVNSQWENGANLDDPPKGALKKLIHAAKLNVSLKSLEGERNHIIIQLS-EVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISHATEELETYRKLAKDLEEELERT----VHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTERELKFELLEKDPNALDVSNTAFGREHSPCSPSPLGRPSSETRAFPSPQTLLEDPLRLSPVLPGGGGRGPSSPGNPLDHQITNERGEPSYDRLIDPHRAPSDTGSLSSPVEQDRRM---MFPPPGQSYPDSTLPPQREDRFYSNSERLSGPAEPRSFKMTSLDKMDRSMPSEMESSRNDAKDDLGNLNVPD------------SSLPAENEATGPGLIPPPLAPISGPLFPVDTRGPFMRRGPPFPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYLHPRPGFYPNPTF-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8IX94-1", "uniprot_id": "CTGE4_HUMAN", "id": "Q8IX94-1", "name": "cTAGE family member 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLWRSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEAT---------CEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLS-EVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISRATEGLETYRKLAKDLEEELERT----VHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHSPCSPSPLGRPSSETRAFPSPQTLLEDPLRLSPVLPGGGGRGPSSPGNPLDHQITNERGEPSYDRLIDPHRAPSDTGSLSSPVEQDRRM---MFPPPGQSYPDSTLPPQREDRFYSNSERLSGPAEPRSFKMTSLDKMDRSMPSEMESSRNDAKDDLGNLNVPD------------SSLPAENEATGPGLIPPPLAPISGPLFPVDTRGPFMRRGPPFPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYLHPRPGFYPNPTF-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CG41-1", "uniprot_id": "CTGE8_HUMAN", "id": "P0CG41-1", "name": "cTAGE family member 8", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLWRSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEAT---------CEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLS-EVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKISRATEGLETYRKLAKDLEEELERT----VHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHSPCSPSPLGRPSSETRAFPSPQTLLEDPLRLSPVLPGGGGRGPSSPGNPLDHQITNERGEPSYDRLIDPHRAPSDTGSLSSPVEQDRRM---MFPPPGQSYPDSTLPPQREDRFYSNSERLSGPAEPRSFKMTSLDKMDRSMPSEMESSRNDAKDDLGNLNVPD------------SSLPAENEATGPGFIPPPLAPVRGPLFPVDTRGPFMRRGPPFPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYLHPRPGFYPNPTF-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86UF2-1", "uniprot_id": "CTGE6_HUMAN", "id": "Q86UF2-1", "name": "cTAGE family member 6", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLWRSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEAT---------CEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGEVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLS-EVDKTKEELTEHIKNLQTQQESLQSENIYFESENQKLQQKLKIMTEFYQEDEMKLYRKLTVEENYRIEEEEKLSKVEEKLSRATEQLETYRKLAKDLEEELERT----VHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHAPNGPAPLGQRSSETRAFLSPQTLLEDPLGLSPVLPEGGGRGPRGPGNPLDHQITNERGEPSCDRLTDPHRAPSDTGSLSSPVEQDCKM---MFPPPGQSYPDSALPPQREDRFYSNSERLSGSAEPRSFKMTSLDKMDGSMPSEMESSRNDAKDDLGNLNVPD------------SSLPAENEATGPGFIPPPLAPVRGPLFPVDTRGPFMRRGPPFPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYFHPRPGFYPNPAF-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A4D2H0-1", "uniprot_id": "CTGEF_HUMAN", "id": "A4D2H0-1", "name": "cTAGE family member 15", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEPGATPQPYLGLVLEELRRVVAALPESMRPDENPYGFPSELVVCAAVIGFFVVLLFLWRSFRSVRSRLYVGREQKLGATLSGLIEEKCKLLEKFSLIQKEYEGYEVESSLEDASFEKAAAEEARSLEAT---------CEKLNRSNSELEDEILCLEKDLKEEKSKHSQQDELMADISKSIQSLEDESKSLKSQIAEAKIICKTFKMSEERRAIAIKDALNENSQLQTSHKQLFQQEAEVWKGQVSELNKQKITFEDSKVHAEQVLNDKENHIKTLTGHLPMMKDQAAVLEEDTTDDDNLELEVNSQWENGANLDDPLKGALKKLIHAAKLNVSLKSLEGERNHIIIQLS-EVDKTKEELTEHIKNLQTQQASLQSENIYFESENQKLQQKLKIMTEFYQENEMKLYRKLTVEENYRIEEEEKLSRVEEKLSRATEQLETYRKLAKDLEEELERT----VHFYQKQVISYEKRGHDNWLAARTAERNLSDLRKENAHNKQKLTETELKFELLEKDPNALDVSNTAFGREHAPNGPAPLGQRSSETRAFLSPQTLLEDPLGLSPVLPEGGGRGPRGPGNPLDHQITNERGEPSCDRLTDPHRAPSDTGSLSSPVEQDCKM---MFPPPGQSYPDSALPPQREDRFYSNSERLSGSAEPRSFKMTSLDKMDGSMPSEMESSRNDAKDDLGNLNVPD------------SSLPAENEATGPGFIPPPLAPVRGPLFPVDTRGPFMRRGPPFPPPPPGTMFGASRGYFPPRDFPGPPHAPFAMRNIYPPRGLPPYFHPRPGFYPNPAF-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96RT6-1", "uniprot_id": "CTGE2_HUMAN", "id": "Q96RT6-1", "name": "cTAGE family member 2", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRPDSHPYGFPWELVIRAAVAGFFAVLF-LWRSFRSVTSRLYVRREKKFAVALSGLIEEKCKLLEKFSLVQKEYEGYEVESSLKNASFEKEAT-EAQSLEAT---------CEKLNRFNSELVHEILCLEKELKEEKSKHSEQNELMADISKRIQSLEDESKSLKSQVAEAKMTFKRFQANEERLEIEIQDAWKENSELQESQKQLLQ-EAEVWKEQVSELIKQKRTFEDSKVHAEQVLNDKENHIKTLTERLLKMKDGVAMLEEDVTDDDNLELEMNSESEDGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLS-EVDKTKEELTEHIKNLQTEQASLQSENTHFESENQKLQQKLKVMTELYQENEMKLYRKLIVEEKCRLEKEEKLSKVDEMISHATEELETYRKRAKDLK-EFEKT----IHFYQKKIILHEKKAHDNWSAAWTAERNLNDLRKENAHNRQKLTEIEFKIKLLEKDPYGLDVPNTAFGRQHSPYGPSPLGWPSSETRASLYPPTLLEGPLRLSPLLPRGGGRGSRGPGNPPDHQITKERGESSCDRLTDPHRAPSDAGPLAPPWEQDYRM---MFPPPGQSYPDSALPPQRQDRFYSNCARLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDNLGNLKVPD------------SSLPAENEATGPGFVPPPLAPIRGLLFPVDTRGPFIRRGPPFPPPPPGTVFGASPDYFSPRDVPGPPRAPFAMRNVYLPRGFLPYRPPRPAFFPPAPTF----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96PC5-3", "uniprot_id": "MIA2_HUMAN", "id": "Q96PC5-3", "name": "Melanoma inhibitory activity protein 2", "aln": "-----------MAKFGVHRILLLAISLTKCLESTKLLADLKKCGDLECEALINRVSAMRDYRGPDCRYLNFTKGEEISVYVKLAGEREDLWAGSKGKEFGYFPRDAVQIEEVFIS--EEIQMSTKESDFLCLLG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VSYTFDNEDSELNGDYG--ENIYPYEEDKDEKSSIYESDFQIEPGFYATYESTLFEDQVPALEAPEDIG---------------------------------STSESKDWEEVVVESMEQDRIP--EVHVPPSSAVSGVKEWFGLGGEQAEEKAFESVIEPVQESSFRSRKIAVEDENDLEELNNGEPQTEHQQESESEID-------SVPKTQS----ELASESEHIPKPQSTGWFGGGFTSYLGFGDEDTGLELIAEESNPPLQDFPNSISSDKEATVPCTEILTEKKDTITNDSLSLKPSWFDFGFAILGFAY----------AKEDKIMLDDRKNEEDGGADEHEHPLTSELDPEKEQEIETIKIIETEDQIDKKPVSEKTDESDTIPYLKKFLYNFDNPWNFQNIPKET---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPFPKQILDQNNVIENEETGEFSIDNYPT-DNTKVMIFKSSYSLSDMVSNIELPTRIHEEVYFEPSSSKDSDENSKPSVDTEGPALVEIDRSVENTLLNSQMVSTDNSLSSQNYISQKEDASEFQILKY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LFQIDVYDFMNSAFSPIVILTERVVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEAT-EAQSLEAT---------CEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLKIAIKDALNENSQLQESQKQLLQ-EAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLS-EVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERT----IHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPNTAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLDHQITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRM---MFPPPGQSYPDSALPPQRQDRFCSNSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPD------------SSLPAENEATGPGFVPPPLAPIRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFAMRNVYPPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQQET", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I5ZSK4-1", "uniprot_id": "A0A8I5ZSK4_RAT", "id": "A0A8I5ZSK4-1", "name": "Melanoma inhibitory activity protein 2", "aln": "-----------MAEVSVQRILLLVISLAKCLEGTKLLAHLKKCGDLECETLITRVLALRDHTGPDCRYLNFTTGEEISVYVKLGGDREDLWAGSKGKDFGFFPRDAVEIEEVFIS--EEVEMPTKESDFLCLLG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EGYIFGSEQSEFISDDDGEEHMYPYEKDEDQHYNIYEDDFQPEHDFYEASEGSLPEDQISASEAAEDFR---------------------------------FSSKWKDWEGTASEGTGEQDYTPDPDQALPSLSTPERQGWFGLGIEEAEEKTFEPDTEPTQESSFQSRKLTLEEESDLEKLHDGEPQGELEQEPKSQFDSETSEFSSAPEEQF----DLASGSESAPNPKASGWFGGGFTSYLGFGNEGAELEPLSEESHLPLQDVPSPVSPDEDAPAPCRETSTVKEDTVVNDSSVLSPSWFYFGFGMLGFTN----------ADEDK-IISDNGENEDGEVDDLKHPTKNDFDPEKEQKR------KTEDQTGKESTLEKIDDSGSMQYLKKFFDN---PWGFQNRPEDT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPFSKQRLDEDDIVGSDKTEELLTENSPTGSMRDSMMSRSRYSLSDVASETESPTGVHEGINFKSSSSERNEEDSKSWVDPEELSVAQTE-SLEGALLETQLVS------------PNERAAEFQLLKY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLHIDVYSFMRSAFSPIEILLESVVAALPEDMRADFNPNGFSLELAICVLTVGLLAIVLFLWRGFRSIRSRFYVGREKKLALELSALIEEKCKLLEKVSFVQKEYEG--LESSLKEASFEKEST-EAQSLEFVEGSQISEAAYENLERSKSKLEDEILLLEKKLEEERVKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKTTFRIFEINEERLRGAIKDALNENSQLQESQKQLLQ-EAEIMKEQVSDLDKQKVTLEESRAQAEQVLSEKETQIESLIKSLLKMKDWAAVLGDDTADDGNLDLDMKSGLEDTASLDNQPKGALKKLIYAAKLNASLKALEGERNQIYTQLS-EVDQIKEDLTEHIKSLESKQASLQSENTEFESESQRLQQKLKVITELYQENEMKLHRKLTVEENYRLEKEEKLSKVDERISHAAEELETYRQRAKDLEEELERT----IHSYQGQVISHEKKAHDNWLAARTLERNLNDLRKENAHNRQKLTETEFKFELLEKDPYALDVPNTAFGREHSPYGPSPLGRPPSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPENLLDHQMNTERGDSSYDRLSDAPRAPSDR-SLSPPWEQERRMT--AHPPPGQPYSDPVP--QRQDRFYSNSGRLSGPAELRSYNMPSLDKVDGPVSSEMESSRNDTKDNLGNSNVPD------------SPHPTESEAAGRGFIPPPFPPVRAPLFPVDPRSQFMRRGPSFPPPPPGNIYTAPRDYFPPRDFPGPPLPPFPGRTVYAPRGFPPFLPPRAGFFPPPPHHENRSELPPDMSPPSKEPAADPPETQET-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZV0-1", "uniprot_id": "MIA2_MOUSE", "id": "Q91ZV0-1", "name": "Melanoma inhibitory activity protein 2", "aln": "-----------MAEVSVQRILLLVVSLAKCLEGTKLLAHLKKCGDLECETLISRVLALRDYTGPDCRYLNFTTGEEISVYVKLGGDREDLWAGSKGKDFGFFPRDAVEIEEVFIS--EEVEMPTK-SDFLCLLG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EGYIFGSEQSELNSEDD-EEHMYPYEKDEDQNYNIYEGDFQPEPDLYAAAEGTLLEDQIPASEAPDDFR---------------------------------FSSEWKAWEGAGSQGGGEQDYTADSDQDLPSLSKPERQGWFGLGTEEAEEKVFESDTEPTQE-------LALEEESDLEKLHSGEPQVELEQEPKS----ETLEFSSVPDEEY----ELESETESILKPQASGWFGEGLTSYLGFGNEEAGLELLSKESNPPLQDIPSSVPPDEEVPAPCREISTDKEDAVINDSSVLSPSWFYYGFGMLGFTN----------ADEDN-IVSDKGENEDGEVDNLKHPIGSDFDPEKEQERK-IVTVETEDQAGTESVLEKTDESGSMQYLKKFFDN---PWGFQSLPEDT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELPFSKKMLDQDDIVENDKIEELSTENSPTGSMKDPVMLASRYVLSDIDSEVELPMEEHEGVHFKPSSSKRNEDDSNSWADPEELSVAQTDGSAEGALLDTQLVS------------PKEHAADFQLLKY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLQIDVYGFMSSALSPIEILLESVVAALPEDMRADFNPSGFSLELAVCVLSVGLLAVVLFLWRGFRSIRSRFYVGREKKLALELSALIEEKCKLLDKVSIVQKEYEG--LESSLKEASFEKEST-EAQSLEFVEGSQISEATYENLEQSKSKLEDEILLLEEKLEEERAKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKTTFRIFEINEERLKGAIKDALNENSQLQESQKQLLQ-ETEMMKEQVNDLDKQKVALEESRAQAEQALSEKESQIETLVTSLLKMKDWAAVLG--EADDGNLDLDMKSGLENTAALDNQPKGALKKLIYAAKLNASLKALEGERNQVYTQLS-EVDQVKEDLTEHIKSLESKQASLQSEKTEFESESQKLQQKLKVITELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETCRQRAKDLEEELERT----IHSYQGQVISHEKKAHDNWLAARTLERNLNDLRKENAHNRQKLTETEFKFELLEKDPYALDVPNTAFGREHSPYGPSPLGRPPSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPENLLDHQMNTERGESSYDRLSDAPRAPSDR-SLSPPWEQDRRMT--AHPPPGQPYSDPAL--QRQDRFYPNSGRLSGPAELRSYNMPSLDKVDGPVPSEMESSGNGTKDNLGNSNVPD------------SPIPAECEAAGRGFFPPPFPPVRDPLFPVDPRSQFMRRGPSFPPPPPGSIYAAPRDYFPPRDFPGPPLPPFPGRTVYAPRGFPPYLPPRAGFFPPPPHPESRSELPPDLIPPSKEPAADPPETQEA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB13AB75-1", "uniprot_id": "A0AB13AB75_DANRE", "id": "A0AB13AB75-1", "name": "", "aln": "-------------MAAVHSFILFQMFFGFLHQGLALISDYKFCGDPECERMISRVQAQRDHVTKDCRFLNFKKGDIITVYYKLTGKRNDLWAGSTEKLFGLFPKDAIKVDQLFIDEKKEIQVPTQEFDFMCFDENGVVIEPSTEFDDTEDLTQETQENNINEVYDTPNDDTEETEPIQISPQDVSNQNSPETTEKGGSSWIGSAVSGWFGRNEQSNAEPQDESSEESFKSRKIVMDIEERHAEEKENSGAFGWLSGELTNAFGFGNQDLKTDAQENIDTPTDDKQTNSWMSMGRDALGFGEDNSAETEAQKAEENPNMEDQSLINPNQSMENDPDEDESEKVEEQTGWYGGIYNQITNLYGEEQTKHDENDDEILPEEKKPEFATDIKNIETKESEPSSQSIFSVSGLASVMKLPFQEDVVVKTDEEQTGKSEDPGKGDFDEEQSNEDREEKEMITDVNEQDSVATDTDMFNETQMVSDKTKTMAVTESDSTQQLDGKSNASEESTFTFNADVLVEDVKQDVQNNEAVNISKDDYNEKRNTNKDQEEEMLSDVNEEDQNPKDILGETPDKTMAHLKDSIDTDSTEQIKERSNASEESANSKILESKSADNLNEVKNEYNADVIDVKQDIENNEENTAKDVNIGKEENTRKDQEEETVTDVNEQNLKTTDSDVLGENQLLSEETVAFLKDTAESDSTEQLDEKSNKTEETFTHLRILEKKSEDKSENSADVLEVEKDMRDMQKDEEKSAKEVILGKDFFEQLNVMEDKMSDADKLESISEADLISETHTSDETMILKDSVSSDDIRELNDSSPDINIQNENEVELADNSISGVIQSENYLTDSVDDISQSKLTPNLSDQENVDTTKQQENDYDQFNTERITSADTSKQLQVEIHDQKSQELNVSYSYSDSQTEMVIISEDVKADEISELTVSDVLLNYDNEKQLNDKDATEHDGLTMDRNDGLVMDRTDVLVNDRLVMNRNDGLVMDRTDELVNDGLVMDRNDGLVMDRTDELVNDGLVMDRNDRLVVDNKDGLVTDRNDGLDRNDELVMDKNDGLVMDINDGLDTGGNDESVKDQNDGLVTDRNDGLVVDNKNGLVTDSYDGLDKNDGLVMDINDGLDTGGNDESVKDQNDGLVTDRNDGLVVDNKDGLVTDRNDRLDKNDGLVMDIKDGLDTGRNDESIKDQNDGFVTDRNDGLVVDNNDGLDRNDGLVVDNNDGLDRNDGLVVDNNDGLDRNDGLVVDNNDGLDRNDGLVMDINESLMDKNDGLVMDINDGLETDRNYESVTNKNDRLVMDRNDGIETDRNYESVMDKNNGLVMDRFDGLDTDKSVMDKKDELVMDINNGLVMGIKDESLTNKNDGLVMDSTNGLDMDRNYNLAINRNDNVVMDRKEVQFVEALSKDITFDEEKLPDSEPLDISNEDELSTEINSLDEGRDQIHLEPNSAPNTTNDEINNTMESHDGSVEKAGISKDTDSERKYTDKVKIHEEQEEPKTVSEPTEIEFETKEIKEDTHNKNGYTTNTSEGFGVSKNDGHDLDIPEKTDNGNIFNTDSNGHKASTEPNLTSHFFSKEEPVLDDSTNYITLDQNQTVEHKEETANDDNHQTKSEYVRKREKRDTGVIHVQSNDADMAVHSQDEQEEQLGRPQHKKTFSHSPENFKVYKNLHFHLSEQNIQDLSDLFGDHKLSWLDSKMENTHTGPDNNDLEELSDFEQLLEYYMKMNTKLGLIQQDNRPGEDNDNNKEYPALQKLLTLLSTLKKTYSAAIADINVERQGISKDECFHEACLDVNKDTVISSKEVENNPVIAEMSDINDLSSPQNEPVSQKKEISSSRAIVKDVQSEQIRKEEDWTSSDIKKTTAQNHVLFSEELVESQNGEGYFYHMAVFVEDTIYEIASIVVKVVSSLPDDIRPGPDLYGLPWEAVFFTGFLGLSILLLFTCRFIQSIKSRLYASKEKQMAHKMAELLDEKCKVLETFSEVKQKFDK--LESTLQNNGMSARAAEKDTLEVAS----------QKLEQSNAQMKKEIERLQEELSQQNKARKQQEDQLAELEQILRNLEEEAKERKSQLEQDNTTLKIHEINTERLQKNLLAAKEEHTMLLESKEQLMQ-EAEGWGERLSELEEEMKMCERSHAGMMEDCANKDDRIKSLTECLLKMRDWDSEDETSIDGSTNIAGAAN-----GDSSDFHQKQKVQKLIEAAKMSADLKSLEEDKNRVFAKLA-DEIKAKEDLHEGIKQLEEQKELLVSESANYSSESQKLQQKLQIMTEMYQENELKLHRMLTVEEKERLQKEEKLNKAGKKISLAAEELNTYRQRAKDLEDELDRT----SQAFKNQISSHEKKAHDNWLAARAADRDLADVKRENAHLRQRLTDAQFRFDILEKD---VREGRPIFRGERSPYGPSPLGRPSSETRTFLSPPTLMDGPPRLSPQFMGPG-RASRGVVEPPSGGPEFERSGP-----------HSDSGSLSPSWDRERRG---PPVPPGHPLPDPGLPYRRPPPGPYPMGPLPPRPPLPPEQYFGDKSDSSFLRNSSSISEHEGREGSGDMRLPP------------DPDSRMGPLPPPGPPLMSMPPPMDPRDPHFPHRGPFGPPDYFPPRGPHVLPMGMRGPLPPGMFPRAPVPFPQHMGFLPPRAPSDSFTHGPPPRPSPPGSEQPPDQPPAPHDAI--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMA7-1", "uniprot_id": "TGO1_DROME", "id": "Q9VMA7-1", "name": "Transport and Golgi organization protein 1", "aln": "MRLTNEKATMQPQLSDLALVLGLLICCLPTLTWAATLSDKRLCADPKCEQIISMGIAKITYAIGGEGLISFKINSPIRVLSKSAGSNMQLWGVDINGRRGYANKDFIMEKKILVRDKDLLYEVPVVGPGS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVQSVETPVQSVETTVQPVLNASESTDDLATTTTSPLEIAVDSIVVEHDKLQDQQVPDPTAASKAQVQVIEG-------------------------TELPLEAIAATTEGSIVPETAADPQEATNLDSTVVDTKEPQALNSEAIKLQEEPKAQQPATEAEKPPPLPQAINAELEDADDFDYGDDETD-DDSQQGSQDNESIVEIANDNKSINESIELKPLSVAQLKKTDKVEDSKDETKEKHAEMEVSKQEDSSLPTETLNVTALEEQIDQKEFPKQVLDAAVELKSSDPLPVEEVTETVAEPPRTIVEDKINEEIVPVSAKIQAKPATVNPTEPIVAQSDAEIKAPSESVIS-STTPAPVVEEAPQKADPVGLPPLFEKKNFENPNNYYKQLQEEQEKQRLVAEAEEQKR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQEEADQQKRLQEEAALNKRLLEEAEQQKRLQEEAEQQKRLQEEAELN---KRLLEEAEKQKRLHEESEQLQRSSEEAEPQLSVQEANMQQLNDSVDSQSNE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IVDNNNRQQPEQYQQHHHHTESAFNHPSTASHTTPTPDAESPYAAVQEETTEASQTDNHREGVGYVEPVALPATASPVSEVPIKEDAAGFGLFATIVDTVNNFIGKDPQSDPADSSDELHRILYPGRPEVP----------PSQRKAEDFAPADVDGYCARFQAKDEHCHRSISLDNFVEVMADKLVDHSQLLLCVVIAAISSLFFMFAYYCFCNSSQEGALLSKLNHLERSLLASHKENLIIKHDLMTTRTKLASIEDNSFGSNDMVADLKKQLESELYEKAKLQEQVGSLERDLDNAAEAGLELNKMLSEVLNGQNGDEAFMSTVDELQRQLNDQEKIIIEINNSLAEKSRENSELQYTFTEATTRLNSELKTLQEDNYELEMEKSKLQTR---LQEIQAETESELAKALEARNYEMQKLQNQIVELTVKWEREHGDLQTSLAKIEALEDCLKAVGKDAIHNVQELITSAKTRGELNAVHKKLVELQS-KVEQEEAHKQR--LESQLQQSSQDVEQLKQDFNQSERDKLEAQTRLEVLSGYFREKENDLKKELSLQETKWLQHQGENASTVETQTLMKNEIQTLKSQNDELRAEIEAQIASHKAQMGTLENRAHESWLAARQSERRCEEALAEAASLRRKLTTMASGGGGVGGDPGVMEAIAANGTSVLGAELKTAPSPLPLPGSPLLNMPNPLPFLAAPFSPFMGLPPPFLPPTGAGGARPPPLGRMRSPPPSSRGDRDRERYSDYSDYDDYDDDEEDDRGMDRRRRHSGSWGRRHRGSYSHSPRTYRSLSPSDSRYNYNDTETDFSPPPSPPPVPSGRSATSRPYSEV---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : . . .. :: .. ::: :* : . . . : : :: :. : .. . :. .* :.:: . : * .: : * : : * . : : . :::: ::: . . : : : : :..: : . : : : *. : : : : : : * . *: : * .:. . *..:** : : *: * * :* : * ..: : :::: . . *:* : *: :. . : : : :.:.. * : : .:.:*:** :: : ::: . : : .. .: *. *.. :: . *. . . : :.. :: .* ... .. .:. :: : . . . . . . : * . . * .: . . . . ** . . ", "identical_positions": 32, "similar_positions": 181, "identity": "1.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100618-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O15091-1", "uniprot_id": "MRPP3_HUMAN", "id": "O15091-1", "name": "Mitochondrial ribonuclease P catalytic subunit", "aln": "MTFYLFGIRSFPKLWKS-PYLGLGPGHSYVSLFLADRCGIRNQQRLFSLKTMSPQNTKATNLIA-KARYLRKDEGSNKQVYSVPH-FFLAGAAKERSQM-------NSQTEDHALAPVRNT--IQLPTQPLNSEEWDKLKEDLKENTGKTSFESWIISQMAGCHSSIDVAKSLLAWVAAKNNGIVSYDLLVKYLYLCVFHMQTSEVIDVFEIMKARYKTLEPRGYSLLIRGLIHSDRWREALLLLEDIKKVITPSKKNYNDCIQGALLHQDVNTAWNLYQELLGHDIVPMLETLKAFFDFGKDIKDDNYSNKLLDILSYLRNNQLYPGESFAHSIKTWFESVPGKQWKGQFTTVRKSGQCSGCGKTIESIQLSPEEYECLKGKIMRDVIDGGDQYRKTTPQELKRFENFIKSRPPFDVVIDGLNVAKMFPKVRESQLLLNVVSQLAKRNLRLLVLGRKHMLRRSSQWSRDEMEEVQKQASCFFADDISEDDPFLLYATLHSGNHCRFITRDLMRDHKACLPDAKTQRLFFKWQQGHQLAIVNRFPGSKLTFQRILSYDTVVQTTGDSWHIPYDEDLVERCSCEVPTKWLCLHQKT----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8JZY4-1", "uniprot_id": "MRPP3_MOUSE", "id": "Q8JZY4-1", "name": "Mitochondrial ribonuclease P catalytic subunit", "aln": "MTFYLSGFRSIPKLWKSNPYFELGPATSSTPFFL---CAIGNQQRWFSVKPTTPPNSKALNLLDTKARTHRKGNDNNGQVSSDPH-YFAAGAAKKRSHIG-----ANPQNQGHALP-VRSS--VQLPTKPLNSAEWDKLKEDFKG---KASFEDFIISQMARNCCSVDVAKSLLAWVAAKNNGIVGYNLLVKYLYLCVFHKQTSEVIDVYEIMKAKYKSLESGGYTLLIRGLIHSDRWRESLLLLEDIKKVMVPSKKNYGDCIQGALLHQDVNTAWNLYQELIGHNLIPPLETLKAFFDYGKDINDDHYSDKLLDILLYLRNNQLYPGESFAHSIKTWFESIPGRQWKGQFTTIQKSGQCSGCGRTIEPIHLSPEEYEFLKEKIMRDVIDGGDQYKKTTPQELKRFESFVNSCPPFDIVIDGLNVAKMFPKGRESQNLLGVVSQLAQQNLQLLVLGRKHMLRPSSQWRKEEMEQVRKQAHCFFADNISEDDPFLLYATLNSGNHCKFITKDLLRDHKACLPDARTQRLFFKWQQGHQLAIMKGFQKSKLTFQHILSYDTVVQRTGDSWHIPYDEDLVQRSSCEVPTKWLCLQRKTPDPC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "X1WBZ5-1", "uniprot_id": "X1WBZ5_DANRE", "id": "X1WBZ5-1", "name": "Mitochondrial ribonuclease P catalytic subunit", "aln": "-----MGFVAMSKSRTCMKHLCTWVVN---PLYFRPDSPPHNITNAVRLIIN-PHTRYYTTKRDKQAQSPNEKGFTPRTRPAFPHSVFSAGAARKRAEFLKHKSGLDTENDDTPVR-VRDSPNMVLPDRPLTPSEWTNLKKDFSR---PELFEKVMMENLVRANVDVNIAKSLLSYVVQ-DKGTLSYEILLRYLTICVRAGHHSEVFDAYDIMRSCFKSLDLGASALFIKGFSQTDRWKEAISMLQDMKKALLPSPRNYGDVIAGAVLHGDSETSWKLYDELLELGLVPGQDTWQCLFQSG--ITQRGHEDKLFDVLSYMRDNQIYPEKPLMETIKAWFESLPDQKWRGKFSSVTPSGDCRNCKALLESIQLTEVEYAQLKHNVMEKVIEGGDVFNKSNPEELKSFKSFVKQRPPFDIVIDGLNVAKMLPHAAQSETLLAVVSELEQQSLNILVLGRKHMLRHSRNWDRQNMSLIKQKAHCFFTEDISEDDPYLLYAALNSGVHCKFLSRDLMRDHKACLPDSATRCLFFKWQRGHQLVISHYTPGKRVRFERILSYDTIIQTNGSSWHIPYDQKAEDRASYEVPQKWLCLTRD-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: ::.* .. :: .::: . * . . : * . . :*: .: . : ** * ****::*:.: :.:.:. .: **.: : ** :**.. ** :**:*:. **. ::.::. .:::*****::*. ::* :.*::*::** :** : ***:*.::**:: :*:*: . :*:*:*: ::***:*:: :*:*:**.: ** :**.* * **:** * :*:*:**:**: .::* :* :.:*: * *.: :.:**:*:* *:*:**:** :.: .:**:****:*.::*:*:*::: **:* .* :*.*:*: ** ** ::*..**:*** :.*:.*:*** *:.*::. ****:**********:*: :*: ** ***:* ::.*.:********** * :* :::*. ::::* ***:::******:****:*:** **:*:::**:*********: *: ******:****.* : .:: *::******::* .*.*******:. :*.* *** ***** :. ", "identical_positions": 229, "similar_positions": 208, "identity": "38.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100623-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q03350-1", "uniprot_id": "TSP2_MOUSE", "id": "Q03350-1", "name": "Thrombospondin-2", "aln": "-----MLWALALLALGIGPRASAGDHVKDTSFDLFSISNINRKTIGAKQFRGPDPGVPAYRFVRFDYIPPVNTDDLNRIVKLARRKEGFFLTAQLKQDRKSRGTLLVLEGPGTSQRQFEIVSNGPGDTLDLNYWVE-GNQHTNFLEDVGLADSQWKNVTVQVASDTYSLYVGCDLIDSVTLEEPFYEQLEVDRSRMYVAKGASRESHFRGLLQNVHLVFADSVEDILSKKGCQHSQGAEVNTISEHTETLHLSPHITTDLVVQ-----GVEKAQEVCTHSCEELSNMMNELSGLHVMVNQLSKNLERVSSDNQFLLELIGGPLKTRNMSACVQEGRIFAENETWVVDSCTTCTCKKFKTVCHQITCSPATCANPSFVEGECCPSCSHSADSDEGWSPWAEWTECSVTCGSGTQQRGRSCDVTSNTCLGPSIQTRTCSLGKCDTRIRQNGGWSHWSPWSSCSVTCGVGNVTRIRLCNSPVPQMGGKNCKGSGRETKPCQRDPCPIDGRWSPWSPWSACTVTCAGGIRERSRVCNSPEPQYGGKDCVGDVTEHQMCNKRSCPIDGCLSNPCFPGAKCNSFPDGSWSCGSCPVGFLGNGTHCEDLDECAVVTDICFSTNKAPRCVNTNPGFHCLPCPPRYKGNQPFGVGLEDARTEKQVCEPENPCKDKTHSCHKNAECIYLGHFSDPMYKCECQIGYAGDGLICGEDSDLDGWPNNNLVCATNATYHCIKDNCPKLPNSGQEDFDKDGIGDACDEDDDNDGVSDEKDNCQLLFNPRQLDYDKDEVGDRCDNCPYVHNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPYVYNTDQRDTDGDGVGDHCDNCPLMHNPDQIDQDNDLVGDQCDNNEDIDDDGHQNNQDNCPYISNSNQADHDNDGKGDACDSDDDNDGVPDDRDNCRLVFNPDQEDSDGDGRGDICKDDFDNDNVPDIDDVCPENNAITETDFRNFQMVPLDPKGTTQIDPNWVIRHQGKELVQTANSDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQTYWEDKPSRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTEGQVRTLWHDPKNIGWKDYTAYRWHLIHRPKTGYMRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKYECRDA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A2G6-1", "uniprot_id": "D4A2G6_RAT", "id": "D4A2G6-1", "name": "Thrombospondin-2", "aln": "-----MLWALALLALGIGPRAYAGDHGEDTAFDLFSISNINRKTIGAKQFRGPDPGVPAYRFVRFDYVPPVNTDDLNRIVKLARRKEGFFLTAQLKQDRKSRGTLLVLEGPGTSQRQFEIVSNGPGDTLDLNYWVE-GHQHTNFLEDVGLADSQWKNVTVQVASDTYSLYVGCDLIDSVTLEEPFYEQLEADKSRMYVAKGASRESHFRGLLQNVHLVFADSVEDILSKKGCQHSQGAEVNTISEHTETLHLSPHITTDLVVQ-----GVEKAQEVCTHSCEELSNMMNELSGLHVMVNQLSKNLERVSSDNQFLLELIGGPLKTRNMSACVQEGRIFAENETWVVDSCTTCTCKKFKTVCNQITCSPATCANPSLVEGECCPSCSHSADNDEGWSPWAEWTECSVTCGSGTQQRGRSCDVTSNTCLGPSIQTRTCSLGKCDTRIRQNGGWSHWSPWSSCSVTCGVGNVTRIRLCNSPVPQMGGKNCKGSGRETKACQRAPCPIDGRWSPWSPWSACTVTCAGGIRERTRVCNSPEPQYGGKDCVGDVTEHQMCNKRSCPIDGCLSNPCFPGAKCNSFPDGSWSCGSCPVGFLGNGTHCEDLDECAVVADICFSINKASRCVNTNPGFHCLPCPPRYKGTQPFGIGLEDAKTEKQVCEPENPCKDKTHNCHKHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSDLDGWPNSNLVCATNATYHCVKDNCPKLPNSGQEDFDKDGIGDACDEDDDNDGVSDEKDNCPLLFNPRQLDYDKDEVGDRCDNCPYVHNQAQIDTDNNGEGDACSVDIDGDDVFNERDNCPYVYNTDQRDTDGDGVGDHCDNCPLMHNPDQMDQDNDLVGDQCDNNEDIDDDGHQNNQDNCPYISNSNQADHDNDGKGDACDSDDDNDGVPDDRDNCRLVFNPDQEDSDGDGRGDICKDDFDNDNVPDIDDVCPENNAITETDFRNFQMVPLDPKGTTQIDPNWVIRHQGKELVQTANSDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQTYWEDKPSRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTEGQVRTLWHDPKNIGWKDYTAYRWHLIHRPKTGYMRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKYECRDA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35442-1", "uniprot_id": "TSP2_HUMAN", "id": "P35442-1", "name": "Thrombospondin-2", "aln": "-----MVWRLVLLALWVWPSTQAGHQDKDTTFDLFSISNINRKTIGAKQFRGPDPGVPAYRFVRFDYIPPVNADDLSKITKIMRQKEGFFLTAQLKQDGKSRGTLLALEGPGLSQRQFEIVSNGPADTLDLTYWID-GTRHVVSLEDVGLADSQWKNVTVQVAGETYSLHVGCDLIDSFALDEPFYEHLQAEKSRMYVAKGSARESHFRGLLQNVHLVFENSVEDILSKKGCQQGQGAEINAISENTETLRLGPHVTTEYVGP-----SSERRPEVCERSCEELGNMVQELSGLHVLVNQLSENLKRVSNDNQFLWELIGGPPKTRNMSACWQDGRFFAENETWVVDSCTTCTCKKFKTICHQITCPPATCASPSFVEGECCPSCLHSVDGEEGWSPWAEWTQCSVTCGSGTQQRGRSCDVTSNTCLGPSIQTRACSLSKCDTRIRQDGGWSHWSPWSSCSVTCGVGNITRIRLCNSPVPQMGGKNCKGSGRETKACQGAPCPIDGRWSPWSPWSACTVTCAGGIRERTRVCNSPEPQYGGKACVGDVQERQMCNKRSCPVDGCLSNPCFPGAQCSSFPDGSWSCGSCPVGFLGNGTHCEDLDECALVPDICFSTSKVPRCVNTQPGFHCLPCPPRYRGNQPVGVGLEAAKTEKQVCEPENPCKDKTHNCHKHAECIYLGHFSDPMYKCECQTGYAGDGLICGEDSDLDGWPNLNLVCATNATYHCIKDNCPHLPNSGQEDFDKDGIGDACDDDDDNDGVTDEKDNCQLLFNPRQADYDKDEVGDRCDNCPYVHNPAQIDTDNNGEGDACSVDIDGDDVFNERDNCPYVYNTDQRDTDGDGVGDHCDNCPLVHNPDQTDVDNDLVGDQCDNNEDIDDDGHQNNQDNCPYISNANQADHDRDGQGDACDPDDDNDGVPDDRDNCRLVFNPDQEDLDGDGRGDICKDDFDNDNIPDIDDVCPENNAISETDFRNFQMVPLDPKGTTQIDPNWVIRHQGKELVQTANSDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFYVVMWKQVTQTYWEDQPTRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTPGQVRTLWHDPRNIGWKDYTAYRWHLTHRPKTGYIRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQEMVYFSDLKYECRDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B7K3-1", "uniprot_id": "A0A8M3B7K3_DANRE", "id": "A0A8M3B7K3-1", "name": "", "aln": "MILRRCFRLLALLLLFTSVKSQDAQLEDETIFDLFESSGITRKTIGVKLFKGLDSDAPAYRFIRFDQLPSVSSTALQQLLLQIQNNEGFILTATLRQDRTSRGTILALEGPGE-RRQLEIVSDGRTNTLDLVYWWADGSRNVISFEEVDLSDSQWKNITLYVHGETATLYIGCGLIDSFILDEPFYEHLSATGASMFVAKGSTRESHFRGLLQNVRFIFDTQLEDILESRGCDLGNPVEANKVSESAEFVEVPSSIATNVIGQNTDVPATSSSELMCERSCEELANLFQELKGLRVVVSNLIDGLQKVTEENTAMKEALNKMQSLSEQSMCWQDGRMFEDKEDWIVDSCTKCTCQEGKVVCRQITCPPVACANPSFIDGECCPVCLP-MDSEDGWSPWSEWTQCTVTCGSGTQQRGRSCDDTSNTCSGPSIQTRKCSLGKCDRRVRQDGGWSLWSPWSSCSVTCGEGLITRIRHCNAPVPQRGGKDCEGEGRETQSCHTDPCPIDGGWGPWSPWAACSATCGGGLKSRVRECNSPEPQHGGRKCLGDSIENEVCNRLECPIDGCLSNPCFSGVECNTASDGSWECGPCPNGYRGNGTSCEDVNECNMVSDLCHKVGGLQQCVNTDPGFHCLPCPPRYKGTQPYGMGVESAKTNKQVCEPYNPCKDNSHSCHKFAECIFLSHFTDPMYKCECRIGYAGDGIICGEDFDLDGWPNQDLVCGANATYHCKKDNCPTLPNSGQEDFDNDGQGDACDKDDDNDEIVDERDNCPLMYNPRQYDYDKDDVGDRCDNCPYEHNPAQTDTDNNGEGDACSVDMDGDEILNERDNCPLIYNTDQKDTDLDGVGDQCDNCPLVHNPQQTDSDNDLVGDQCDNNQDIDEDGHQNNMDNCPYIPNANQADHDGDGKGDACDFDDDNDGIPDDRDNCRLVPNKDQEDSDGDGRGEACENDFDNDNVPDIFDACPENSGISVTDFRKFQMVHLDPKGTTQIDPNWVVRNQGKELVQTANSDPGIAVGFDEFSAVDFSGTFYVNTDRDDDYAGFVFGYQSSRRFYVVMWKQITQTYWEEKPSKAFGISGVSLKVVNSTTGTGEILRNALWHTGNTKHQVRTLWHDPKNIGWKDFTAYRWHLIHRPKTGFIRVVVYEGKQIMADSGPVYDKTFAGGRLGLFVFSQEAVFFSDLKYECRDN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *.** * : .. .:* ****. *.*.*****.* *:* *...*****:*** :*.*.: *.:: :.:***:*** *:** .****:*.***** :**:****:* :**** ** * ::. :*:*.*:******:*: * .:* :*::**.****. *:*****:*.. : *:****::************:::* .:****..:**: .: .* * :** :* :.: . ::*: : . . :* :*****.*:.:**.**:*:*.:* ..*::*:.:* : * :. . : * * *:**:* ::* *:*****.***:: *.:*.****.*.:**.**:::***** * *.::*****:***:*:*************** ***** ******* ***.*** *:**:**** ************ * :**** **:**** ***:*:*.****:.*: ****** *.*****:**:.**.**::.* * *******:**: *:** *.::**: .**:*********.*.:*.: .****.**.** *: **** ***::** :*.*:*.. . :****:************:*.** *:*:* *:*:****** *****::*.*** ****:*.**:********: ******:***** ******* :***.:****** ***** **********:** *****.***** : **:*** *::**** *****:********** ** ** **************:***:::******* :*****:*** *****:******:***:* * ************:***:****** ******.*:****** **:***** ******:********** * **** ******: *::******:*** *.****..*: ****:**** **************:*:**********************.:*************************** *********:******::*::*:* **************** *********** *********:******:******* ******::**:*:****:******:**:*:************* *:********** ", "identical_positions": 777, "similar_positions": 246, "identity": "65.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100624-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CIQ7-1", "uniprot_id": "DOCK3_MOUSE", "id": "Q8CIQ7-1", "name": "Dedicator of cytokinesis protein 3", "aln": "-------MWTPTEEEKYGVVICSFRGSVPQGLVLEIGETVQILEKCEGWYRGVSTKKPNVKGLFPANYIHLKKAIVSNRGQYETVVPLEDSIVTEVTTTLQEWASLWKQLYVKHKVDLFYKLRHVMNELID--LRRQLLSGHLTQDQVREVKRHITVRLDWGNEHLGLDLVPRKDFEVVDSDQISVSDLYKMHLSSRQSVQQSTSQVDTMRPRHGETCRMPVPYHFFFSLKSFTYNTIGEDSDVFFSLYDMREGKQISERFLVRLNKNGGPRNPEKIERMCALFTDLSSKDMKRDLYIVAHVIRIGRMLLNDSKKGPA-------HLHYRRPYGCAVLSILDVLQSLTELK---EEKDFVLKVYTCNNESEWTQIHENIIRKSSTKYS---APSASHGLIISLQLFRGDMEQIRRENPMIFNRGLAITRKLGFPDVIMPGDIRNDLYLTLEKGDFERGGKSVQKNIEVTMYVLYADGEILKDCISLGSGEPNRSSYHSFVLYHSNSPRWG-EIIKLPIPIDRFRGSHLRFEFRHCSTKDKGEKKLFGFAFSPLMRDDGTTLSDDIHELYVYKCDENSTFNNHALYLGLPCCKEDYNGCPNIPSSLIFQRS-KESFFISTQLSSTKLTQNVDLLALLKWKAFPDRIMDILGRLRHVSGEEIVKFLQDILDTLFVILDD---NTEKYGLLVFQSLVFIINLLRDIKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDCSAELIRQDHIQEAMRALEYLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRNSETLLFTQ-------------------------------AALLNSFPTIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSFSESRRILLPVVLHHIHLHLRQQKELLICSGILGSIFSIVKTSSLEADVMEEVEMMVESLLDVLLQTLLTIMSKSHAQEAVRG-HCP-VTAEITGEYVSCLLS-LLRQMCDTHFQHLLDNFQSKDE---LKEFLLKIFCVFRNLMKMS--VFPRDWMVMRLLTSNIIVTTVQYLSSALHKNFT-ETDFDFKVWNSYFSLAVLFINQPSLQLEIITSAKRKKILDKYGDMRVMMAYELFSMWQNLGEHKIHFIPGMIGPFLGVTLVPQPEVRNIMIPIFHDMMDWEQRKNGNFKQVEAELIDKLDSMVSEGKGDESYRELFGLLTQLFGPYPSLLEKVEQETWRETGISFVTSVTRLMERLLDYRDCMKGEETENKKVGCTVNLMNFYKSEINKEEMYIRYIHKLCDMHLQAENYTEAAFTLLLYCELLQWE-DRPLREFLHYPSQTEWQRKEGLCRKIIHYFNKGKSWEFGIPLCRELACQYES--LYDYQSLSWIRKMEASYYDNIIEQQRLEPEFFRVGFYGRKFPFFLRNKEYVCRGHDYERLEAFQQRMLSEFPQAVAMQHPNHPDDAILQCDAQYLQIYAVTPIPDYVDVL-QMDRVPDRVKSFYRVNNVRKFRYDRP--FHKGPKDKDNEFKSLWIERTTLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELRALISQYQHKQVHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKDYITKHP--GDAEKISQLKELMQEQVHVLGVGLAVHEKFVHPEMRPLHKKLIDQFQMMRASLYHEF------------------PGLDKLSPACS-----------------------GTSTPRGNVLASHSPMSP--E--NIKM----------THRHSPMNLMGTGRHSSS--------SLSS-----------HASSEAGNMMMMGDNSMGEAPEDLYHHMQLAYHNPRYQGSVTNVSVLSSSQASPSSSSLS-------STHSAPSQMITSAPSSTR--------------GSPSLPDKYRHAREMMLLLPTH--RDRPSSAMYPAAILENGQPPNFQRALFQQVVGACKP------CSDPNLSMAEK-------------------------------------------GHYSLH---------FDAFHHPLG----DTPPALPARTLRKSPLHPIPASPTSPQSG--------------LDGSNSTLSGSASSGVSSLSESNFGHSS-EAPPRTDTMDSMP-----SQAWNGD-EGLEPPYLPVHYSLSESAVLDAIKSQPCRSHSAPGCVLP-------------QDPMDPPALPPKPYHPRLPALEH------------------DEGMLLREEAE-RPRGLHRKASLPPGSVKEEQARLAWEHGRGEQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GLI7-1", "uniprot_id": "A0A8I6GLI7_RAT", "id": "A0A8I6GLI7-1", "name": "", "aln": "-------MWTPTEEEKYGVVICSFRGSVPQGLVLEIGETVQILEKCEGWYRGVSTKKPNVKGLFPANYIHLKKAIVSNRGQYETVVPLEDSIVTEVTATLQEWASLWKQLYVKHKVDLFYKLRHVMNELID--LRRQLLSGHLTQDQVREVKRHITVRLDWGNEHLGLDLVPRKDFEVVDSDQISVSDLYKMHLSSRQSVQQSTSQVDTMRPRHGETCRMPVPHHFFFSLKSFTYNTIGEDSDVFFSLYDMREGKQISERFLVRLNKNGGPRNPEKIERMCALFTDLSSKDMKRDLYIVAHVIRIGRMLLNDSKKGPA-------HLHYRRPYGCAVLSILDVLQSLTELK---EEKDFVLKVYTCNNESEWTQIHENIIRKSSTKYS---APSASHGLIISLQLFRGDMEQIRRENPMIFNRGLAITRKLGFPDVIMPGDIRNDLYLTLEKGDFERGGKSVQKNIEVTMYVLYADGEILKDCISLGSGEPNRSSYHSFVLYHSNSPRWG-EIIKLPIPIDRFRGSHLRFEFRHCSTKDKGEKKLFGFSFSPLMRDDGTTLSDDIHELYVYKCDENSTFNNHALYLGLPCCKEDYNGCPNIPSSLIFQRSTKESFFISTQLSSTKLTQNVDLLALLKWKAFPDRIMDILGRLRHVSGEEIVKFLQDILDTLFVILDD---NTEKYGLLVFQSLVFIINLLRDIKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDCSAELIRQDHIQEAMRALEYLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRNSETLLFTQ-------------------------------AALLNSFPTIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSFSESRRILLPVVLHHIHLHLRQQKELLICSGILGSIFSIVKTSSLEADVMEEVEMMVESLLDVLLQTLLTIMSKSHAQEAVRGQRCPQCTAEITGEYVSCLLS-LLRQMCDTHYQHLLDNFQSKDE---LKEFLLKIFCVFRNLMKMS--VFPRDWMVMRLLTSNIIVTTVQYLSSALHKNFT-ETDFDFKVWNSYFSLAVLFINQPSLQLEIITSAKRKKILDKYGDMRVMMAYELFSMWQNLGEHKIHFIPGMIGPFLGVTLVPQPEVRNIMIPIFHDMMDWEQRKNGNFKQVESELIDKLDSMVSEGKGDESYRELFSLLTQLFGPYPSLLEKVEQETWRETGISFVTSVTRLMERLLDYRDCMKGEETENKKVGCTVNLMNFYKSEINKEEMYIRYIHKLCDMHLQAENYTEAAFTLLLYCELLQWE-DRPLREFLHYPSQTEWQRKEGLCRKIIHYFNKGKSWEFGIPLCRELACQYES--LYDYQSLSWIRKMEASYYDNIIEQQRLEPEFFRVGFYGRKFPFFLRNKEYVCRGHDYERLEAFQQRMLSEFPQAVAMQHPNHPDDAILQCDAQYLQIYAVTPIPDYVDVL-QMDRVPDRVKSFYRVNNVRKFRYDRP--FHKGPKDKDNEFKSLWIERTTLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELRALISQYQHKQVHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKDYITKHP--GDAEKISQLKELMQEQVHVLGVGLAVHEKFVHPEMRPLHKKLIDQFQMMRASLYHEF------------------PCLDKLSPACS-----------------------GTSTPRGNVLASHSPMSP--E--NIKM----------SHRHSPMNLMGTGRHSSS--------SLSS-----------HASSEAGNMMMMGDNSMGETPEDLYHHMQLAYHNPRYQGSVTNVSVLSSSQASPSSSSLS-------STHSAPSQMITSAPSSTR--------------GSPSLPDKYRHAREMMLLLPTH--RDRPSSAMYPAAILENGQPANFQRALFQQVVGACKP------CSDPNLSMAEK-------------------------------------------GHYSLH---------FDAFHHPLG----DTPPALPARTLRKSPLHPIPASPTSPQSG--------------LDGSNSTLSGSASSGVSSLSESNFGHSS-EAPPRTDTMDSMP-----SQAWNGD-EDLEPPYLPVHYSLSESAVLDSIKSQPCRSHSAPGCVIP-------------QDPMDPPALPPKPYHPRLPALEH------------------DEGVLLREEAE-RPRGLHRKASLPPGSAKEEQARMAWEHGRGEQ-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IZD9-1", "uniprot_id": "DOCK3_HUMAN", "id": "Q8IZD9-1", "name": "Dedicator of cytokinesis protein 3", "aln": "-------MWTPTEEEKYGVVICSFRGSVPQGLVLEIGETVQILEKCEGWYRGVSTKKPNVKGIFPANYIHLKKAIVSNRGQYETVVPLEDSIVTEVTATLQEWASLWKQLYVKHKVDLFYKLRHVMNELID--LRRQLLSGHLTQDQVREVKRHITVRLDWGNEHLGLDLVPRKDFEVVDSDQISVSDLYKMHLSSRQSVQQSTSQVDTMRPRHGETCRMPVPHHFFLSLKSFTYNTIGEDTDVFFSLYDMREGKQISERFLVRLNKNGGPRNPEKIERMCALFTDLSSKDMKRDLYIVAHVIRIGRMLLNDSKKGPP-------HLHYRRPYGCAVLSILDVLQSLTEVK---EEKDFVLKVYTCNNESEWSQIHENIIRKSSAKYS---APSASHGLIISLQLLRGDMEQIRRENPMIFNRGLAITRKLGFPDVIMPGDIRNDLYLTLEKGDFERGGKSVQKNIEVTMYVLYADGEILKDCISLGSGEPNRSSYHSFVLYHSNSPRWG-EIIKLPIPIDRFRGSHLRFEFRHCSTKDKGEKKLFGFAFSTLMRDDGTTLSDDIHELYVYKCDENSTFNNHALYLGLPCCKEDYNGCPNIPSSLIFQRSTKESFFISTQLSSTKLTQNVDLLALLKWKAFPDRIMDVLGRLRHVSGEEIVKFLQDILDTLFVILDD---NTEKYGLLVFQSLVFIINLLRDIKYFHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDCSAELIRQDHIQEAMRALEYLFKFIVQSRILYSRATCGMEEEQFRSSIQELFQSIRFVLSLDSRNSETLLFTQ-------------------------------AALLNSFPTIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSFSESRRILLPVVLHHIHLHLRQQKELLICSGILGSIFSIVKTSSLEADVMEEVEMMVESLLDVLLQTLLTIMSKSHAQEAVRGQRCPQCTAEITGEYVSCLLS-LLRQMCDTHFQHLLDNFQSKDE---LKEFLLKIFCVFRNLMKMS--VFPRDWMVMRLLTSNIIVTTVQYLSSALHKNFT-ETDFDFKVWNSYFSLAVLFINQPSLQLEIITSAKRKKILDKYGDMRVMMAYELFSMWQNLGEHKIHFIPGMIGPFLGVTLVPQPEVRNIMIPIFHDMMDWEQRKNGNFKQVEAELIDKLDSMVSEGKGDESYRELFSLLTQLFGPYPSLLEKVEQETWRETGISFVTSVTRLMERLLDYRDCMKGEETENKKIGCTVNLMNFYKSEINKEEMYIRYIHKLCDMHLQAENYTEAAFTLLLYCELLQWE-DRPLREFLHYPSQTEWQRKEGLCRKIIHYFNKGKSWEFGIPLCRELACQYES--LYDYQSLSWIRKMEASYYDNIMEQQRLEPEFFRVGFYGRKFPFFLRNKEYVCRGHDYERLEAFQQRMLSEFPQAVAMQHPNHPDDAILQCDAQYLQIYAVTPIPDYVDVL-QMDRVPDRVKSFYRVNNVRKFRYDRP--FHKGPKDKENEFKSLWIERTTLTLTHSLPGISRWFEVERRELVEVSPLENAIQVVENKNQELRSLISQYQHKQVHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKDYINKHP--GDAEKITQLKELMQEQVHVLGVGLAVHEKFVHPEMRPLHKKLIDQFQMMRASLYHEF------------------PGLDKLSPACS-----------------------GTSTPRGNVLASHSPMSP--E--SIKM----------THRHSPMNLMGTGRHSSS--------SLSS-----------HASSEAGNMVMLGDGSMGDAPEDLYHHMQLAYPNPRYQGSVTNVSVLSSSQASPSSSSLS-------STHSAPSQMITSAPSSAR--------------GSPSLPDKYRHAREMMLLLPTY--RDRPSSAMYPAAILENGQPPNFQRALFQQVVGACKP------CSDPNLSVAEK-------------------------------------------GHYSLH---------FDAFHHPLG----DTPPALPARTLRKSPLHPIPASPTSPQSG--------------LDGSNSTLSGSASSGVSSLSESNFGHSS-EAPPRTDTMDSMP-----SQAWNAD-EDLEPPYLPVHYSLSESAVLDSIKAQPCRSHSAPGCVIP-------------QDPMDPPALPPKPYHPRLPALEH------------------DEGVLLREETE-RPRGLHRKAPLPPGSAKEEQARMAWEHGRGEQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YXG5-1", "uniprot_id": "A0A8M6YXG5_DANRE", "id": "A0A8M6YXG5-1", "name": "", "aln": "-------MWTPTEDEKIGVVVCSFRGSVSHGLTLELGETVQILEKCEGWYRGFSTKKPSIKGIFPAGYVHLKKAVVSNRGQYETVVPLEDPIITEVTSTLQEWSVLWKQLYVKHKVDLFYKLRHVMNELID--LRRQLLSGHLTQDQVREVKRHITVRLDWGNEHLGLDLVPRKEFEMVDADQISVSDLYKMHLSSRHSVQQSTSQ-DGGRQRHGETCRMPVPHHLFVNLKSFTYNTIGEDTDIFFSLYDLREGKQISEKFMVKLNKNGGPKNPEKVDRLCALFTDLSNKDMKRDLYIVSQVIRTGRMLLNDSKKGPP-------HVQYRRPYGCAVLAMSDVLQTISELK---EEKDFVLKVYTCNNENEWYQIHENIIRKSSTKYT---APSTNYGLIISLQLLRGDMEQVRRENPMIFNRGVAITRKLGFPDVIMPGDIRNDLYLTLERGDFERGGKSVQKNIEVTMYVLYADGEILKECISLGSGEHNISEYRSFVLYHNNSPRWS-EVVKLPIPIDRFRGSHLRFEFRHCSTKDKGEKKLFGFAFTPLMREDGTTLSDESHELYVYKCDENTTFSNHALYLGLPCCKDDFNGCPNIPSSLIFQRSTKETLWISTQLSSTKLTQNVDLLALLKWKAHPDHVMDILGRLRHVCGEEIVKFLQDILDTLFSILDD---NTDKYGPLVFQSLVFIINLLRDSKFYHFRPVMDTYIQKHFAGALAYKELIRCLKWYMDRSAEVVRQDHIQEAMRALEYLFKFIVQSRILYSRATCGMEEDQFRASIQELFQSIRFVLSLDSRSSETLIFTQGPQATTGQASTNQGNCLQPLSCNAPRPSPLSAALLNSFPAIFDELLQMFTVQEVAEFVRGTLGSMPSTVHIGQSMDVVKLQSIARTVDSRLFSFPESRRILLPVVLHHIHLHLRQQKELLICSGILSSIFSIIKSSSLESSVQEEVEMMVESLLDVLLQTLLAIMSKSQSQEAVRGQRCPQCTAEITGEYVSCLLS-LLRQMSDIHFQHLLDNFQSKEE---LKEFLLKIFCVFRNLMKLS--IFPRDWNVMRLLTSNIIVSTTQYLSPALHKSFT-DADFDFKVWNSYFSLAVLFINQPSLQLETLTPAKRKKVFDKYGDMRVMMAYELFSMWQNLGENKIHFIPGMIGPFLGVTLVPQNEVRNIMIPIFHDMMDWEQRKNGNFKQVEAELIDKLDSLVSEGKGDENYRELFSLLTQLFGPYPSLLEKIEQETWRETGISFVTSVTRLMERLLDYRDCMKGDETENKKIGCTVNLLNFYKSEINKEEMYIRYIHKLCDMHLQAENYTEAAFTLLLYWELLHWE-ERPLREFLHYPAQSEWHRKEGLCRKVIHYFNKGKCWEYGIPLCRELAFQYES--LYDYQSLSWIRKMEAAYYDNIMEQQRLEPEFFRVGFYGRKFPFFLRNKEFVCRGHDYERLEAFQQRMLGEFPQAIAMQHPNQPDEGILQGDAQYLQIYAVSAVPENMDVL-QMDRVPDRIKSFYRVNNVRRFRYDRP--FHKGPKDRENEFKSLWIERTTLILTHPLPGISRWFEVDKRELVEVSPLENAIYVVENKNQELRTLISQYQHKQLHGNINLLSMCLNGVIDAAVNGGIARYQEAFFDKEYISSHP--EDTEKITQLKDLMQEQVHVLGVGLAVHEKLVHPEMRPLHKKLIDQFQMMRSSLCHCFYVA-----------LQGLPGLDKLSPACS-----------------------GASTPRG-ILATHSPMSP--E--SIKL----------MHRHSPLNVLGSVRHSSS--------SLSS-----------HTSSETGNLLIMTD-SMMEHPEDLYR-----------------------MQPSPSSSSLS-------STHSAPSQMINSGHGSIRV-------------GSPSLPDRYRHNREMLMLLPPH--RDRPSSAMYPNITENGQVPTNHQRALYHQVIGPCKP------CSDPNLSVADKVLSAPSSWSLDSGTRDTLPFLSAHVGSVMAPPVPPRTLPP---GHFSMH---------FDAFHHQIN----ELPPALPARSLRKSPLHPIPASPTSPQSG--------------LDGSNSTLSGSASSGVSSLSESNFAQSSSEPPARADTLDSMPS----SQAWTTDTEEAESPYLPVRYSVSEPEVLDPLKPAPCRSHSAPLGVTPG----------IPSDGHHHHHLHLHHHHPHAVHITHPHYHHHEPAPALPPKPYLREGCIPEEDLRPVPRPMPRKISQPLLTTKEEQAKVAWEHGISEE-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VAS8-1", "uniprot_id": "Q9VAS8_DROME", "id": "Q9VAS8-1", "name": "", "aln": "-------MWIPS-NNKYGVAIHNWHGDVRFGLALDVGDSVDIVEECKHWYRGSCPRKSRAVGLFPKTYIHIKDLSK------------IDPVVAECTQVLREWSEIWKRLYVDREAYKFQTLRKVMFSILE--SRRELLSATMTQDQTLELQMVVVSKIDWGNRKLGLDLVPREGPLAVDPHGIGIVKLYNVHVSSADNAKASSSRGTLRR----KTQRKILTHHLYFCMRDFGHRIGGDDAEVYFFLYDGSHMRPLSERFLVKISKDGFSNYIERLHSNCTVFTDLGAADLNEELHLVAVVMRVGKIIQSDSIKKIEKSGTLGHGPTFRRPFGVGVLSLGDIAHFDSSLEQSSDEREYNFKLFQCE-EKDFHLLPELIIKKSSGKYSPIQASQGTQGIVVSLKLLHGGLGQARQEQPMLF-QGSTITRKMGFPDVIMPGDVRNDLFLNLERGEFERGGKNTGKNILVTVVVLDVAGNVLTDCLWGASGMESQPQYRSMILYHQNAPSWN-EMLRLSVPIDKFSTAHVRFEFRHCSTRDKTEPKLFAFSFARLMDTGGATLGDGLHELYVYKCEDPAKLQ-VANYLRLQCRPRDAQ--AKMDCGGCFSRSSKEVFVLRSLLCSTKLTQNADLLSLLQWRTYPETIQDSLTGVLRLNDEELVKFLQDVLDALFAMFSNEEGNSTQHSGLVFHVLVSIFSLLQSNKFQHFRPVMNEYIENHFAAALVYKGLITSVEHMAVFMTKAEHPDPFQKCFGSLEYIFKLLIQSRKLFARATGGQYEDSFKRDLHSLFTALNGMLAVPS--YDVIIPTQ-------------------------------EALLNSTGVVLEQLKDTLPAPELGMLARNMLDAIPRGAPIR--LIQAKLHAVKDLVSGELFHEDDSRTVVLSVACKHLRMHLSRRDELRLCAEILSEILSQLYD--LQKEQREKVTNTLQHDLDSLCKNILGILIRTIS-------IIMEGSNAVLPQLVSCLLG-LLQLLDETHYKRYWDELSPNKDPRDLKEFLSKSLLVYEELLTQDWHVFPNDWLVMKLAANDVLRMSLEEFAKPLVYRFLGPQAFDSQLWWSYFSLAVAFLTQPSLQLEQYREPKRLKILHSHGDMRVLMGFQILSMWSQLGEQKLHFIPSMVGPFLEVTLVPEPALRKATLSVFYDMMQCEQAARGSFRLVESELIDKLDLLISENKGDDEYRELFSTILLEK-------VQVENPNWKEAGIAFIASVTRLLERLLDYRSVMQGEENRDKRMTCTVNLLNFYKNEINRKEMYLRYIYKLHNLHLQAENYTEAGFTLKLYASMLSWDRETQSFAPFDNSGQPEWQRKERLYHEILKYFDKGKCWEKGIPLCKELAHLYETR-RFDYNKLSEILIQEAKFFQNILTQLRPEPEYFRVGFYGMGLPLFVRNKQFVYRGLEYERIGAFTQRLQTEFPSAQILGNNSPPDNAILNAPDQYIQISNVRPVGDAQALKTAMVPVPEKIARFYEVNDVTRFIYDRP--MYKGTVDKDNEFKSLWIERTILEIASPLPGILRWYEVKQKTMQELTPVEYACEIISNAGKELSELIVQYKRDPKR-NINPFSMRLQGTIDANVMGGISKYQEAFFSEQFLKSPQGAGQQANVQRLKVLILEQIQILEQALELHGQLAPSGVQPLHNRLLERFSQLKQSLSGMGRLKRQHSESIVNTPLPPLPTEQRVAPATASSSLNANAHSNYVYDLDEIYTRPGDTVRPVDPLSSYQTLSK--E--SLSIPLEDTAAPPVPNRPRSQNFIGNGSMDSPEVPPKRQPTLNSPNAPPLPPRGITPDKRASNPLIFNDFGSGDAVGRRHSQQQQQHGQKYSVVDISYDDPEADQQPHSLPPNFQDGSGGHLSVCFAPNDFRDSGISTTSSRELNHMNLNNLSEDSSSISTITVQHREHCRISSNG--SLDYNAAASMNITQRESSTSSFDVEDFPVPPPPIPPKSLAVSSNGVNFSLDEAHSPHPSTQANTTQLNHIQNPNQNHSTN----------------SHHHLQQQQNGDGDGYSTLQHPMNGLGLPTLPPPPSAVESPMPASAIASSTSSHQHDGGTFXVTICRCHHPPDQPHQPHKPSSSTSTSDSTATDTASESTESSSSTHSMTPPPPPPPPPSSFTHLHHQMAATTHYCQDCLSSPSPPPTIITEQAQVHPTPGSTSAQPHIEHCSCGLSFSVVQDQQEQFPRLLSTRFSTLER-----------------QTDGFQVEQVSGCQHHHHHQHSPLYHLPQSSQDAHAQTDFSYAQR-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06409-1", "uniprot_id": "DCK1_YEAST", "id": "Q06409-1", "name": "DOCK-like protein 1", "aln": "MSQQDSQRWLPTDRLIYGVLVKSFLPLQRYPELVYENSNYANVYVGAEVYVFEESVDKKWCRAYQCLRPFPEEFISN--------MNSANDVLPDVKPKVVIFPRKYVHFEAEKAVSTMPFFKAPSAEDFKPLISKECESRSFCDSLYVSSTDDISTGKPRKTPRPPFPFFRYQKRSFKDEMGPILSLISSHVYSMYSIGEFSIYRKMIKLYYDLDTIRFRLSMNLTTEAEKINLIRAATSLRTKIAKFLSSTYR-KNKLIANSTPRNPDPYGFEGIFARDIDTGELLSYEIDKLRTLVSSSMLCGLTNNFPTVPVVESD----DESSSNGLFGTVRSSILVNLKDLAWDPSISDPKYQDLSICVYLRTKDEVLTESFTMTKSSNMES--------ALDEIPAMLFKNILETIVHKNKVYLVVVLKETIAITTETAPEISSYNISTEESSSHSPFSPFNSSTENKIDHVKKGLAAGVINISPVFKFYNGLSVANKAQRFNLYLYSSDSSDSQNFNSSKDADLGWGGLINKIIKDSSEGVSVNPRAVSLSVT-VKEIIGKQEAEKVLSTSLVPIRSIPTYFYDTMFSQAERIYLNLGRVSLYGLPAADTNIENVTVQISCRNKAVKFCKNKLEERSGDWKFVSVRPNESIGESIRIEG--VENMNEDETLRVLVYLNG------------FLMAKSNIHIKKKNEIIEYRKGTVFQIMSSKSVPLIHLELEASY-----FGRRYNINPAITNFLVLQTKNVEFDQQLKEHYSVTLKQLNNVSFKDLLKHFDTILAHYLLLLESVNEATDKKG--------------------------------PSSSLPNIVFSEFVKFLNLMLTHQENSRYWFNRLYKKVMSKELECPNVAPILIKHMTTIFDRSHSSWTRTGTAICRTILYIIVLAIGSSHSDEMPNFSHFFRSLHKFLMLADEPIMADQILLIESIPSMLETMTNHCKVEDLVRFAIGLFECCQEKEMNQKMYSRPLSVREEEYLNTKFNCLLKLINKKVLQNYLTNTESVDKLRLQFLS--KTLEWLLTPYTPGDDKCFHVESLRLVNSVFITIIEDYKFDMLQRNLIRLLPYLCKSFVHLRRY--CKKARLMRPRRVFTMLFPREIPCNYIPVDSIVNDEVVVEVLLELAIIICEITKIASSRFPSYQSFSEIIN-------LCDKDTLFQSNFYSRQITNENVYTITKTVFLFFK--------QDWFPGMKWLGVSALLGRSSLILLSLCKDYIIENNSPSPSKE--------------SEKRVDMRLWAEYVKVILLVSNHKSASLTKLAITPRKAVY-----LISGDLKKISAYILNECWDALATGHYNITYAKKYGLGALSDCQFELFVHNQFLIREIFIFAFHRHIDATRICCKILWGLGLNFWRIFGSLQPAVNACIPELFSAYQIGKLRLNDYELERFVSCLFFMMHVPDSDTFFPACMDFLRDLLGFLHIVNEIYKIPNQEEFDDDRTARHIEMFEYLLEANRPELFHKMIYDLFIHFIQKKDFVQAALSLELLAGTYAWDSNDTLEAISFPPLPEQSSFERKEYLLKESARNFSRGQKPEKALAVYKDLIKAYDEINYDLNGLAFVHDQIAGIYTRLQSIDRLVPTYFKVSFMGFGFPKSLRNKSFVFEGLPFEHITSMHDRLLRSYHGSNIVHSQEE------------------VDMLLMNPPMG-------------------------KYIHVASVEPCLSISDNYNSS---------------DKKSSINNKVRMYIENR-----------------------DLRTFSNSRRLPGAKGVTDLWVEEYTYHT--------------------MNTFPTLMNRS-------EIVKVTKSKLSPLENAIRS-------------LQVKIQELYGLENMCNKTLKDHGDVNDLFTELSTNITGTISAPVNGGISQYKAFLEPSTS----KQFSTDDLG------------------------------------------RLTLA---------------FDELVAVLGRCLTLHAELLPSKDLKPSHDLLVRLFEENFAEE--------------IERYSRTLSEANRSRNNMITARIISHKNPNKKASFSGRDHHTS-----------GSNHSQFVLEHSDSFGPNSLLFGKYLTRTLSHSSTTSSLD------------------------------------------------------KSGIVSG-----------TSSTFLAGSQPNTNTDSQHKHDYSHSG", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *: ** : .: : ... : * . . : . :. : ::.: . : :. : :: ..: . : :: . :. :: * : :. . : . : : :. : * : : . * : * : .* * :. :: ..: . . : : : .: : :: . * : :* ::.. :*: : * : . :* :: : : : : :.: .: . : *** : :. *::. : ::: : : * : . .. . . . .:. *. .... ::* . * . :. : .* . : : ** .: . : .. . * . :. ::..* . : : ..::.: : * .: . : . .. : : : . . : . : :.*: :* .*: . : : :: . : :: :* :: :.. * : : :. : .:* * . : .* : * . . : : : .:: * : :: : : .*: :: : : * : . :. . . . ::.:: . : : : :: .: :* .* .. : ::: : : .: . :: : * .:* : . : . : . * : : : : : : *:::* : * . : . :* : ..: : : : :. .: : : :: :. ::*. *: ::: : ::: :: . : :.. . : : * : : : . :. : .: : : : : : : : : ..:: * : : : *:: : . : *: * ::.:. .: ..:.: :* : .: * ..*:..*.:* . . : :* ::: . : *: : : ..: : . .* : ::* * . : . : :: .: .. : : .* : :: . : : . : : : :** ::* * .* . *.* * . . ...*: . : : . . : . ::. : . : . : : . ::. : : * :. : : .:*.:*: : . : *. . . : . .:* : .: . * .. . :.. : . : : :. . . . . .... . .: . .: . : . . : . . . ::. :. : :. *: : . : . . : : . : . .. : . . ... *.:. .* . . . :: ... .. ", "identical_positions": 87, "similar_positions": 552, "identity": "3.76%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100624-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAR7-1", "uniprot_id": "D4AAR7_RAT", "id": "D4AAR7-1", "name": "", "aln": "MGLGAGTGEGFRAAAGGHSRQVARPGPALSARPLSSLRTGLPVPGPEAAASAREAAAATGAAMEAGGGAGAGAAGWSCPGPGPTVTTLGSYEVSEGCERKKGQRWGSLERRGMQAMEGEVLLPALYEEEEEEEEEEEEEVEEEDQVQKEGSLGSLSVGKHRGLSLTETELEELRAQVLQLVAELEETRELAGQHEDDCLELQGLLEDERLASAQQAEVFTKQIQQLQGELQHLREEISLLEHEKESELKEIEQELHLAQAEIHNLRQAAADSATEHESDIASLQDDLCRLQNELDDMERIRGDYEMEIASLRAEMELKASGPS-DLSISDFSGIQDELHQLRERYHFLNEEYQALRESNSSLTGQLAELESDRTRRATERWLESHMLKNMMSSESQTSELDFPEPDPVMQLLRQQLLGAEEQMHDMQDKCKNLCCELEELQHHRRTSEEEQKRLQRELKCAQNEVLRFQTCHTTQ-NEELKSRLCALQQKYDTSQDEHSELLKVQMQLQSELQQLKLVRCTPVESQSEKELMCRLQKLQAQHQCSVNEKEQLLEVQHHLHDKLRCHESEMHRLREMVDCLRERNEKNSGIHLQLQEMKGLYQCSRDELERQKHMYDQLEQDFMLCQQELTELKSSHSFCEDSGNRPNKCDALLARLTELQEKFKASQLEIGHLQMEQCELLEDQRRLQEEQGQLQEELHRLTFPQPKCGLLQKSQELLAKLQDLCEMQLLYQNMQDQQRKLIQNQECVLREQLEAHKHLRGFKESNFQEVLANPQDAQGPKSSSCEN--KFKVFMEQLQALQVLYDTSQRQQEVLQQEHGRLMEERKRLQAELQLCMEEMQLLQTQSPTMKGNFDYCKKNTGSTALSTESFHRSYDSTIDECEGYQKSYVSSQPSKETFLKSYDSNMSCSEAFQKSYCS-SNTTVAYKKSYISGSSCETLHKSYASSSTDEEPADPEDLEHFEETVAKVLTKLQAVKALYQVSQEEHCQLQERMSKLLAKQKELKEELEYCEKELKECMENFEKPATPQNDKCEIKELQTKLRELQLQYQASMDEQGRLLAVQEQLEGQLQCCQEELRQLKENRSSFSSEARGKHVLKNMNKNANGVR-DQVGKACSEDLENDFEDEKNLEVMLYYKASQKKLDELTKEEKEMDELR--KKEKEKQAKKELCKLAT-KAADPGAEPESTEGEDENFEEYTEGE------------DESCETAEEGNPLKLSESKKNMFGMWKPMVFLAIA-AVALYVLPNMRPQEPEFYMN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TVA9-1", "uniprot_id": "CC136_MOUSE", "id": "Q3TVA9-1", "name": "Coiled-coil domain-containing protein 136", "aln": "----------------------------------------------------------------------------------------------------------------MQAMDGEVLLPALYEEEEEEEEEEEE--VEEEQVEKGGSLGSLSMGKHRGLSLTETELEELRAQVLQLVAELEETRELAGQHEDDSLELQGLLEDERLASAQQAEVFTKQIQQLQGELQHLREEISLLEHEKESELKEMEQELHLAQAEIQNLRQAAADSATEHESDIASLQDDLCRLQNDLDDMERIRGDYEMEIASLRAEMELKTSEPS-NLSISDFSGIQDELHHLRERYNLLNEEYQALRESNSSLTGQLAELESDRTRRATERWLESHLLRSTMSSESQTSELDFPEPDPVMQLLRQQLLGAEEQMQDMQDKCKNLYCELEELQHHRRTSEEEQKRLQRELKCAQNEVLRFQTSHSTQQHEELKSRLCTLQQKYDASQDEHSELLKVQMQLETELQQLRLLRCTPVESQSEKELMCRLQKLQAQHQCSVNEKEQLLEVQHHLHDKLRCHESEVHRLRSMVDCLREKNEKNSGIHLQLQEMKGLYQFSRDELERQKHMYDQLEQDFLLCQQELTELKSSQSLCEENGNCSNKCDALLARLTELQDKFKASQEEIGHLQMEQCELLEDQRRLQEEQGQLQEELHRLTFPQPKCGILQKSQELLSKLQDLCEMQLLYQNMQEQQRKLTQNQECVLKEQLEAHKHLRGFKESHFQEVLANPQDARGPKSSSCEN--KFKVLMDQLQALQVLYDTSQKQQEVLQREHGRLMEERKRLQAELQLCMEEMQVLQTQSPMIKRSFEYCGKNSGSRAPSTENFHRSYESSIDENEGYQKSYVSSQPSTETFLKSYDSSTSANEAFEKSYCS-SSTSVSYKKSYGSVSSGETLHRSYASSSTDEDPAEPEDLEHFEETVAKVLTKLQAVKALYQVSQEEHCQLQQRMHRLLAKQKELTEELQCCEKELRECMESLGKPLPPQSDKCEIKELQTKLRELQLQYQASMDEQGRLLAVQEQLEGQLQCCQEELRQLKENRPSISSEARGKNVNKNMNKNANGVRNKKLSMACSEDLENGFENEKNLEVMLYYKASQRRLDELMKEEKEIEEAR--KKEREKKAKKDLCKLATNPAADPRAEPEPTEDEEENFEEYREGE------------DESCEAAEEGNPLKLSESKKPSPAPDPPIFSLPLVGLVVISALLWCWWAETSS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JN2-1", "uniprot_id": "CC136_HUMAN", "id": "Q96JN2-1", "name": "Coiled-coil domain-containing protein 136", "aln": "----------------------------------------------------------------------------------------------------------------MQAMEGEVLLPALYEEEEEEEEEEEEVEEEEEQVQKGGSVGSLSVNKHRGLSLTETELEELRAQVLQLVAELEETRELAGQHEDDSLELQGLLEDERLASAQQAEVFTKQIQQLQGELRSLREEISLLEHEKESELKEIEQELHLAQAEIQSLRQAAEDSATEHESDIASLQEDLCRMQNELEDMERIRGDYEMEIASLRAEMEMKSSEPSGSLGLSDYSGLQEELQELRERYHFLNEEYRALQESNSSLTGQLADLESERTQRATERWLQSQTLS-MTSAESQTSEMDFLEPDPEMQLLRQQLRDAEEQMHGMKNKCQELCCELEELQHHRQVSEEEQRRLQRELKCAQNEVLRFQTSHSVTQNEELKSRLCTLQKKYDTSQDEQNELLKMQLQLQTELRQLKVMKSTLVENQSEKELLCRLQKLHLQHQNVTCEKEKLLERQQQLQEELQCHEAELQHLRDTVASFKESNEKDTETHAQLQEMKQLYQASKDELERQKHMYDQLEQDLLLCQLELKELKASHPIPEDKGKCANKCDTLLSRLTELQEKYKASQKEMGQLQMEQCELLEDQRRMQEEQGQLQEELHRLTLPLPKSGLLLKSQELLTKLEDLCELQLLYQGMQEEQKKLIQNQDCVLKEQLEIHEELRRFKESHFQEVLENPDDSKLAKSSKCNRNKQSKLLMEQMQALQVMYDAGQAKQELLQQEQGRLLEERKRLQADLQLCLEEMQLLQVQSPSIKMSLESYGKSYGSMVPSNENCRKTYDTTVDDNESYYKSYTSTQTSSKSFLKSYDSSTSASEAYGKSYCTTSNSSITYKKSYGSTSSSDTCQKSFVSSCTDEEPAEPEDMERFEEMVVKVLIKLQAVQAMYQISQEEHSQLQEQMEKLLAKQKDLKEELDACEREFKECMECLEKPMAPQNDKNEIKELQTKLRELQLQYQASMDEQGRLLVVQEQLEGQLQCCQEELRQLREKRPSVVKEARGKNANKNMNKNANGVKMKKVTKPCSDTSESDLETRKSLEVVLYYKASQRKLDGLAKEEEKKEEMEEEKKQVKEEAKEQCGDELVAEPADP-EEAKSTEDQEENEEDKEEEEKEEDSEEEEDDADSSLESPEENNPLRLSESKKSSPTPNPPIFSLPLVGLVVISALLWCWWAETSS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BBU7-1", "uniprot_id": "A0A8M2BBU7_DANRE", "id": "A0A8M2BBU7-1", "name": "", "aln": "------------------------------------------------------------------------------MDCGLRLPPVIEEVLDPADDVCDLKAELPVFGIQMTAKERGSLEHNEERDQEDLDTGNGEKGQEDEQEKKKEEQEELRGAADEEEEEEENELEVLRSQVVQLLLELEETREVSQKHEDSYNELQGLLEEERLASAHQAESFTRQIQRLQAQLRSVQEELDSLEEEKASELWEAQEELRAAQDEVQELQQAAEEAAAERENDIALLQEELCRMRAELERLRGTTQEYELELTTLRAEINMKNQSRE-----QQEKPGGGDVDQLMEECRSLKDERQTLKNDNKELSEKLEILEQQRASSTDS----------------------------------------------------------------------------------------------------------YLALKTQQNDTEKDDEVETEVKAEGFISTLEMEGGKCVDAYTQKNISFEGKPITPTGKSGG-----------------------FSEVFSLRDQLKQAEEKAS-------------------------------------------------------KVQRECEGLKGELMELQGLYESSQR-------ERAELEAELQRYRAELDRLAGRKAQSSTPSSECPILS-----IPFIGMVVILGLIWCCWKELLS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : * .::*: : : * *::* :* . .* .. . *.*** **:**:**: *******:: :***. *******:******:*** **:***:**.:*: ::**:. **.** *** * ::**: ** *::.*:*** ::*:*:*.*** **::***:: :*: :. :**:*:::****:::* . . .: . ::..* *. . *::* ::*::.*..*: :* **.:*: : . * * : .: *:.: :: ::: : : *.: . *: ::*:: . : : : . .: . ::: :** : : .:*: * ..* *** :::** *:.** : :* : * .:* . : : * .:. :* :. : : : *:: :: ", "identical_positions": 128, "similar_positions": 156, "identity": "10.07%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100624-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AAZ9-1", "uniprot_id": "D4AAZ9_RAT", "id": "D4AAZ9-1", "name": "PDZ domain-containing protein 7", "aln": "MARGFTVGFDPLGLGELSSASLSSLSSRGHLGSDSASTATRYLLRKQQRLLNGPSRGIRASSPMGRVILINSPIEANSDESDIIHAVCVEKSPSGRLGFSVRGGSEHGLGIFVSKVEEGSSAERAGLCVGDKITEVNGLSLESTTMGSAVRLLTSSSRLHMMVRRMGRVPGIKFSKEKTTWVDVVNRRLVVEKCSSTPSDSSSEDGVRRIVHLYTTSDDFCLGFNIRGGKEFGLGIYVSKVDHGGLAEENGIKVGDQVLAANGVRFDDISHSQAVEVLKGQTHIMLTIKETGRYPAYKEMVSEYCWLDRLSNGVLQQLSPASESSSSVSSYASSAPCSSGSLPSDRMDVCLGPEDPTSQGPGWGRADTAMQTEPDMGGSRVETWCSVRPTVILRDTAIRSDGPSSTRHLDSALSESPKTALLLALSRPRPPITRSQSHLTLWEEKKQRKKEKSGSSGEKGALQRSKTLMNLFFKGGRQGRPAGDGHREAWTLDSRSPTKVRPRLDLEKAGSVGPVQKFVTWRLRRALITFIASSWPCPADRERGRALLSARSGSPSGQGPNVDEQMQAWESRRPLIQDLARRLLTDDEVLAVTRHCSRYVHEGGVEDLVRPLLAILDRPAKLLLLRDIRSVVAPTDLGRFDSMVMPVEMEAFEALKSRAVGPSALRPTRQDTPPKRHLITPVPDSRGGFYLLPVNSCSEDED-GEIRERLGGLKVSLGASAP--HHKGIPPLQDVPVDAFSLRRGACAPPPQPPPVAPRPPRPNWLLTEPPSREDTQQNQNQTPGQSCSRSRSHSRSRSGSRSRSRSQGRGKSAGCRRSPSPAPITTATSANGRYHRPRKARPLLPRPLDGQVAKVGVRQEPLENGIDQTAEDEAGNATTGELRTVTLSKMKQSLGISISGGIESKVQPMVKIEKIFPGGAAFLCRALQAGFELVAVDGESLEQVTHQRAVDTIRRAYRNKAREPMELVVRVPGPGLLPLSSNLRAIKGQGLAADSSSAHGPIEDTPILT----------QLPPTEARQLRHALSSVQKVPQSTPKLFPIHKDPHNPS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q9W7-1", "uniprot_id": "PDZD7_MOUSE", "id": "E9Q9W7-1", "name": "PDZ domain-containing protein 7", "aln": "MARGFTVGFDPLGLGELSSGSLSSVSSRGHLGSDSGSTATRYLLRKQQRLLNGPSRGIRASSPMGRVILINSPIEANSDESDIIHAVRVEKSPSGRLGFSVRGGSEHGLGIFVSKVEEGSSAERAGLCVGDKITEVNGLSLESTTMGSAVRLLTSSSCLHMMVRRMGRVPGIKFSKEKTTWVDVVNRRLVVEKCSSTPSDRSSEDGVRRIVHLYTTSDDFCLGFNIRGGKEFGLGIYVSKVDHGGLAEENGIKVGDQVLAANGVRFDDISHSQAVEVLKGQTHIMLTIKETGRYPAYKEMVSEYCWLDRLSNGVLQQLSPASESSSSVSSYASSAPCSSGSLPSDRMDVCLGPEEPTSHGPGWGRADTAMQTEPDLD-SRVETWCSVRPTVILRDTAIRSDGPSSTRHLDSALSESPKTALLLALSRPRTPITRSQSHLTLWEEKKQRKKEKSGSSGEKGALQRSKTLMNLFFKGGRQGRPAGDGHREAWTLDSRSPTKVRPRLDLEKAGSVGPVQKFVTWRLRR--------------DRERGRALLSARSGSPSGQAPTVNEQVQAWESRRPLIQDLARRLLTDDEVLAVTRHCSRYVHEGGVEDLVRPLLAILDRPTKLLLLRDIRSVVAPTDLGRFDSMVMPVELEAFEALKSRAVGPSALRPTRQDTPPKRHLITPVPDSRGGFYLLPVNS-SEDED-GEIREKLGVLKVSLGASAP--HHKGIPPLQDVPVDAFSLRRGACAPPPQPPPVAPRPPRPNWLLTEPLSREDTQQNQSQTPAQSCSRSRSRSRSRSHSR------GQGKSPGRRRSPSPAPIATAATANGRYHRPRKARPLLPRLLDGQVAKVGARQGPLEN--GRIAEEAVGNVSTGALRTITLSKMKQSLGISISGGIESKVQPMVKIEKIFPGGAAFLCGDLQAGFELVAVDGESLEQVTHQRAVDTIRRAYRNKAREPMELVVRVPGPGLLPLASDLRVVKDQSLAPDCPSALGPVDDARILT----------QLPPPEARQLQQSLSSALKVPQSIPKLSPILKDPHDPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H5P4-3", "uniprot_id": "PDZD7_HUMAN", "id": "Q9H5P4-3", "name": "PDZ domain-containing protein 7", "aln": "MAQGFAVGFDPLGLGDLSSGSLSSLSSRGHLGSDSGSTATRYLLRKQQRLLNGPPRGIRASSPMGRVILINSPIEANSDESDIIHSVRVEKSPAGRLGFSVRGGSEHGLGIFVSKVEEGSSAERAGLCVGDKITEVNGLSLESTTMGSAVKVLTSSSRLHMMVRRMGRVPGIKFSKEKTTWVDVVNRRLVVEKCGSTPSDTSSEDGVRRIVHLYTTSDDFCLGFNIRGGKEFGLGIYVSKVDHGGLAEENGIKVGDQVLAANGVRFDDISHSQAVEVLKGQTHIMLTIKETGRYPAYKEMVSEYCWLDRLSNGVLQQLSPASESSSSVSSCASSAPYSSGSLPSDRMDICLGQEEPGSRGPGWGRADTAMQTEPDAG-GRVETWCSVRPTVILRDTAIRSDGPHPGRRLDSALSESPKTALLLALSRPRPPITRSQSYLTLWEEKQQRKKEKSGSPGEKGALQRSKTLMNLFFKGGRQGRLARDGRREAWTLDSGSLAKTYPRLDIEKAGGVGPVQKFVTWRLRR--------------DQERGRALLSARSGSPSSQLPNVDEQVQAWESRRPLIQDLAQRLLTDDEVLAVTRHCSRYVHEGGIEDLVRPLLAILDRPEKLLLLQDIRSVVAPTDLGRFDSMVMLVELEAFEALKSRAVRPPALRPARQDTPPKRHLITPVPDSRGGFYLLPVNGFPEEEDNGELRERLGALKVSPSASAPRHPHKGIPPLQDVPVDAFTPLRIACTPPPQLPPVAPRPLRPNWLLTEPLSREHPPQSQIRGRAQSRSRSRSRSRSR-SSR------GQGKSPG-RRSPSPVPTPAPSMTNGRYHKPRKARPPLPRPLDGEAAKVGAKQGPSESGTEGTAKEAAMKNPSGELKTVTLSKMKQSLGISISGGIESKVQPMVKIEKIFPGGAAFLSGALQAGFELVAVDGENLEQVTHQRAVDTIRRAYRNKAREPMELVVRVPGPSPRPSPSDSSALTDGGLPADHLPAHQPLDAAPVPAHWLPEPPTNPQTPPTDARLLQPTPSPAPSPALQTPDSKPAP-SPRIP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AYZ6-1", "uniprot_id": "A0A8M3AYZ6_DANRE", "id": "A0A8M3AYZ6-1", "name": "", "aln": "-------------------------------------------------------------------------MEAETGE---IVRLTVLRGDDGQLGFSVRGGSEHGLSVFISKVQKNSAADVAGLCVGDKLLEVNGVSLENISMSSAVKVLTGHSRLQMLIQRLGRVPGVRYTNEKTTWVDLIHRRMVVEEADAPVSVYSSDGALCRTVHLHLSQNQPCLGLNIRGGREYNLGIYISKLDPGGLAEQGGVKMGDQILSANGVNFENINHHRAVEVLKSQTHVIMTIKEAGRYPAYKEMVTELSWMNKSGSGTVYSSLQDSESSSSSLSSGTPLGSVSG-FSQATLPVSLPLGAKMSNISSSTESQFHPDSTEDDGQPERLRTVSRGPTEVLQDSAIRSRADEDWSGNRESRREGRKTSLLIALSRPSPPIRRTRSHVTISEEEKKQKRKQTEREGGSSPLQRSKTFFGLFHK------------------------------------------------------------------RDSSRSRSRSPPCSESSLAGRCNGDVSEQDSLVPLR-EMAVRLLEDEDVSVLMGICRRYLSERGLQTLVHPLLSILNTPEKLLLLREIRTLVFTSDLPLFNSMVSPFEEEAYDILKSRSRRSSPLRSPQTGLAPRRHLITPVPDLQGGFELQAADDIKRQNQ---LLESLELLRLSCCPADQ---PRSFSPLLDVPLDTFG-------PSDSVNSSRTKALLPNWLLTE------------NRRSESCIPSSA-----------------------VRSESPEDDVLFTVVD----APRHKRPLLAQVFGSLKKSHSSTVSPAEQMCGKKTAPDVHIQPEFELTTVHISKTKQSLGISISGGSESRVQPMVKIERIFPGGAASTSDDLQAGFELVSVDGVSLQDVTHQDAVDIIRQAFSNKSINPMQLVVKVPRD---PRVS----------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**::.* * : * :. *:*************.:*:***::.*:*: ********: ****:***. :*.***::**. * *:*:::*:*****:::::*******:::**:***:..:. * **:..: * ***: :.:: ***:*****:*:.****:**:* *****:.*:*:***:*:****.*::*.* :******.***:::****:**********:* .*::: ..*.: . ****** * .:. ** :.. : :.* *. .. .:: :: * . . * ** :*:*:**** . .: *. **:**:***** .** *::*::*: **::::*:::: * ...******::.**.* :: .*: : . * *. : ::. :* ** ::* *** *::* .: * **: * *:: **:***:**: * *****::**::* .:** *:*** .* **:: ****: ...**..: . .*:********* :*** * ..:. .::: : * * *::* .: :.:.** ***:*:* *. . . .:. ******* . .:* * : ** ** : .: **: ** *.: :.. . . * *. : . . * *: :** *********** **:********:******* . ********:*** .*::**** *** **:*: **: :**:***:** * * ", "identical_positions": 342, "similar_positions": 237, "identity": "32.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100629-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JZZ8-1", "uniprot_id": "A0A0G2JZZ8_RAT", "id": "A0A0G2JZZ8-1", "name": "Protein strawberry notch homolog 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLAVEPTMD---------------------------GDFPPHELPPPG---------------GGIQLQNRLLHCPWWGSFSPPLYPTFSSEN------QQFVSSTPFLGGQSCPETSYPTTATVPSFFSKSS-----------------DFPQDPSCLEDLSNASVFSSSVDSLSDIPDTP-------------------------DFLPADSLNEVP---TIWDVSTTSTTRDKLFLPSVPFSALEDPVTAVSSTPLLVSYQS---HSQPEEEEGEDEEEAEELGHAETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDITYTLALPTSDNGT--LSALQLEAITYACQQHEVLLPSGQRAGFLIGDGAGVGKGRTVAGIIVENYLRGRKKALWFSASNDLKYDAERDLRDIEAPG-IAVHALSKIKYGDNTTSEG------VLFATYSALIGESQAG-GQHRTRLRQILQWCGEAFDGVIVFDECHKAKNAS------STKMGKAVLDLQNKLPQARVVYASATGASEPRNMIYMSRLGIWGEGTPFRTFEEFLHAIEKRGVGAMEIVAMDMKVSGMYIARQLSFSGVTFRIEEIPLSPVFEQVYNRAARLWAEALSVFQQAADWIGLES--RKSLWGQFWSAHQRFFKYLCIAAKVHRLVELAQQELSRDKCVVIGLQSTGEARTREVLDENEGRLDCFVSAAEGVFLSLIQKHFPSTRRR--RDRGGG-KRKRRPRGRGPKASRLTLEAAGVIRISDGSSTESDAGLDSDFNSSPESLVDD-------------------DVVIVDAPTLPTDDRGPLYPLQRDLQGPGVLERVER--------LKQGLLAKVRALGRELPVNTLDQLIHQLGGPECVAEMTGRKGRVVSRPDGSVVFESRAEQGLSIDHVNLREKQRFMSGEKLVAIISEASSSGVSLQADRRVQNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVSAPEYVFLISELAGERRFASIVAKRLESLGALTHGDRRATESRDLSKYNFENKYGARALSRVLATIMG-QTNNRVPLPQGYPGGDAAFFRDMKQGLLSVGIG--SRESRSGCLDVEKDCS-ITKFLNRILGLEVHKQNALFQYFSDTFDHLIEIDKKEGRYDMGILDLAPGINEIHEESQQVFLAPGHPQDGQVVFYK-ISVDRGMKWEEAFTRSLELKG-PYDGFYLSYKVRGSKTSCLLAEQNRGD---------YFTVYKPNIGRQSQLETLDNLCRKFHRVTPEEAREPWESSYALSLEHCSHTTWNQRCRLAQEGKCCAQGLRLRHHYMLCGALLRVWGRIAAVMADVSSSSYLQIVRLKTKDKKKQVGIKIPEGCVHRVLQELQLMDAEVKRRS-----------------AHGL-AARPPTPRAITLPCGP------------------GEVLDLTYSP---PAEPFPAP---------------------PRFAFPSLPPPD--------------PSS--LMLGTRDNATNPVELAHQGCDINFR-------EVLEDMLRSLRAG-----------------------------------------------------------------------------------------------PTETPAP-------LVGVGGGGGGGTERQSVIHFSPP----------FPNS------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TNB8-1", "uniprot_id": "SBNO2_MOUSE", "id": "Q7TNB8-1", "name": "Protein strawberry notch homolog 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLAVEPTMD---------------------------GDFPPHELPPPG---------------GGIQLQNRLLHCPWWGSFSPSLYPTFSSEN------QQFVGSTPFLGGQSCPETSYPTTATVPSFFSKSS-----------------DFPQDPSCLEDLSNASVFSSSVDSLSDIPDTP-------------------------DFLQADSLNEVP---TIWDVSTTSTTHDKLFIPSGPFSAPEDPVTSLSSTPLLISYQS---HSQPEEEEGEEEEETEELGHAETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDITYTLALPTSDNST--LSALQLEAITYACQQHEVLLPSGQRAGFLIGDGAGVGKGRTVAGIIVENYLRGRKKALWFSASNDLKYDAERDLRDIEAPG-IAVHALSKIKYGDNTTSEG------VLFATYSALIGESQAG-GQHRTRLRQILQWCGEGFDGVIVFDECHKAKNAS------STKMGKAVLDLQSKLPQARVVYASATGASEPRNMIYMSRLGIWGEGTPFRTFEEFLHAIEKRGVGAMEIVAMDMKVSGMYIARQLSFSGVTFRIEEIPLSPAFQQVYNRAARLWAEALSVFQQAADWIGLES--RKSLWGQFWSAHQRFFKYLCIAAKVHRLVELAQQELSRDKCVVIGLQSTGEARTREVLDENEGRLDCFVSAAEGVFLSLIQKHFPSTRRR--RDRGGG-KRKRRPRGRGPKASRLSLEAAGVIRISDGSSTESDAGLDSDFNSSPESLVDD-------------------DVVIVDAPTHPTDDRGSLYPLQRDLQGPGVVERVER--------LKQGLLAKVRALGRELPVNTLDQLIHQLGGPECVAEMTGRKGRVVSRPDGTVVFESRAEQGLSIDHVNLREKQRFMSGEKLVAIISEASSSGVSLQADRRVQNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVSAPEYVFLISELAGERRFASIVAKRLESLGALTHGDRRATESRDLSKYNFENKYGARALSRVLATIMG-QTDNRVPLPQGYPGGDTAFFRDMKQGLLSVGIG--SRESRSGCLDVEKDCS-ITKFLNRILGLEVHKQNALFQYFSDTFDHLIEIDKKEGRYDMGILDLAPGINEIHEESQQVFLAPGHPQDGQVVFYKQISVDRGMKWEEALTRSLELKG-PYDGFYLSYKVRGSKMSCLLAEQNRGE---------YFTVYKPNIGRQSQLETLDSLCRKFHRVTVEEAREPWESSYALSLEHCSHTTWNQRCRLTQEGKCCAQGLRLRHHYMLCGALLRVWGRIAAVMADVSSSSYLQIVRLKTKDKKKQVGIKIPEGCVHRVLQELQLMDAEVKRRS-----------------THGL-AARPPTPRAITLPCGP------------------GEVLDLTYSP---PAEAFPTP---------------------PRFAFPSLPPPD--------------PSS--LMLGARDPATNPVELAHQSCDINFR-------EVLEDMLRSLRAG-----------------------------------------------------------------------------------------------PTETPAP-------LVGVGGGG---TERQSVIHFSPP----------FPNS------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2G9-1", "uniprot_id": "SBNO2_HUMAN", "id": "Q9Y2G9-1", "name": "Protein strawberry notch homolog 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLAVGPAMD---------------------------RDYPQHEPPPAGSLLY-----------SPPPLQSAMLHCPYWNTFSLPPYPAFSSDS------RPFMSSASFLGSQPCPDTSYAPVATASSLPPKTC-----------------DFAQDSSYFEDFSNISIFSSSVDSLSDIVDTP-------------------------DFLPADSLNQVS---TIWDDNPAPSTHDKLFQLSRPFAGFEDFLPSHS-TPLLVSYQEQSVQSQPEEEDEAEEEEAEELGHTETYADYVPSKSKIGKQHPDRVVETSTLSSVPPPDITYTLALP-SDSGA--LSALQLEAITYACQQHEVLLPSGQRAGFLIGDGAGVGKGRTVAGVILENHLRGRKKALWFSVSNDLKYDAERDLRDIEATG-IAVHALSKIKYGDTTTSEG------VLFATYSALIGESQAG-GQHRTRLRQILDWCGEAFEGVIVFDECHKAKNAG------STKMGKAVLDLQNKLPLARVVYASATGASEPRNMIYMSRLGIWGEGTPFRNFEEFLHAIEKRGVGAMEIVAMDMKVSGMYIARQLSFSGVTFRIEEIPLAPAFECVYNRAALLWAEALNVFQQAADWIGLES--RKSLWGQFWSAHQRFFKYLCIAAKVRRLVELAREELARDKCVVIGLQSTGEARTREVLGENDGHLNCFVSAAEGVFLSLIQKHFPSTKRK--RDRGAGSKRKRRPRGRGAKAPRLACETAGVIRISDDSSTESDPGLDSDFNSSPESLVDD-------------------DVVIVDAVGLPSDDRGPLCLLQRDPHGPGVLERVER--------LKQDLLDKVRRLGRELPVNTLDELIDQLGGPQRVAEMTGRKGRVVSRPDGTVAFESRAEQGLSIDHVNLREKQRFMSGEKLVAIISEASSSGVSLQADRRVQNQRRRVHMTLELPWSADRAIQQFGRTHRSNQVSAPEYVFLISELAGERRFASIVAKRLESLGALTHGDRRATESRDLSKYNFENKYGTRALHCVLTTILS-QTENKVPVPQGYPGGVPTFFRDMKQGLLSVGIG--GRESRNGCLDVEKDCS-ITKFLNRILGLEVHKQNALFQYFSDTFDHLIEMDKREGKYDMGILDLAPGIEEIYEESQQVFLAPGHPQDGQVVFYK-ISVDRGLKWEDAFAKSLALTG-PYDGFYLSYKVRGNKPSCLLAEQNRGQ---------FFTVYKPNIGRQSQLEALDSLRRKFHRVTAEEAKEPWESGYALSLTHCSHSAWNRHCRLAQEGKDCLQGLRLRHHYMLCGALLRVWGRIAAVMADVSSSSYLQIVRLKTKDRKKQVGIKIPEGCVRRVLQELRLMDADVKRRQ-----------------APALGCPAPPAPRPLALPCGP------------------GEVLDLTYSP---PAEAFPPP---------------------PHFSFPAPLSLD--------------AGPGVVPLGTPDAQADPAALAHQGCDINFK-------EVLEDMLRSLHAG-----------------------------------------------------------------------------------------------PPSEGALG-----EGAGAGGAAGGGPERQSVIQFSPP----------FPGAQAPL--------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13ABF0-1", "uniprot_id": "A0AB13ABF0_DANRE", "id": "A0AB13ABF0-1", "name": "Protein strawberry notch homolog 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPTLATSVVMDT--------------------------EDYLHPEGPQLGS--------------PKFSAPSPPLTSSMESQLYQPNSWAYSQQA------QYNQHYPMQSGRQLQPTPSFMNLDLSDIDFHELVR--------------NGDFSQELPCTDEVA--SLFSSPSDSLLEYPEPS-------------------------GFG-TDSLAQLTGEGPAAQMYWDIPGHSQRPLNLSAFPGRLDELNAILSPSVAGFKAAAAPAPPPEEEEEADDEETEELGHADTYAEYKPSKSTIGISHPDIVVETNTLSSVPPPDITYTLSIPDSTVSTGLLSALQLEAIIYACQQHEVILQNGQRAGFLIGDGAGVGKGRTVAGIILENFLKGRKRALWFSVSNDLKYDAERDLKDIDAPN-IPVFALNKIKYGDTATSEG------VLFATYSALIGESQAG-GQHRTRLKQILDWCKPSFDGVIVFDECHKAKNAT------STKMGKAVLDLQSKLPRARVVYASATGASEPKNMIYMSRLGIWGQGTPFKTFDDFLHAIEKRGVGAMEIVAMDMKVSGMYIARQLSFSGVSFRIEEIALDEEFKLVYNKAARLWAEALELFNRAADTLGLAS--RKSLWGQFWSSHQRFFKYLCIAAKVRRLVDLAHMEMQQGKCIVIGLQSTGEARTREVLDENDGHLDKFISAAERVFQSLVQKHFPTQKPK--REKSAANKRKRKPRGRPSKFPKQRVEVGGVIKISDDSDSDSDE-FDSESNSSPESLQDN-------------------DDVIFVN----------------HINGP--AAKLEE--------LKQRLLHRIAELGKELPLNTLDELIDRFGGPEKVSEMTGRKGRVVRRPDGSVRYESRAEQGLTIDHVNVREKERFMSGEKLIAIISEAASSGISLQADKRVQNRRRRVHMTLELPWSADRAIQQFGRTHRSNQVTAPEYIFLISELAGERRFASIVAKRLESLGALTHGDRRATESRDLSQYNFENKYGTKALDKITKAILG-HIDNKVPPPKGYPGGGLMFFRDMKKGMIDVGIF--CKEPRMG-LNTEKDCT-LTKFLNRILGLEVHHQNFLFQYFTENFDYLIEKDKKEGKYDMGILDLAPGNDEIHEETQEKFLTPGNPQEGQVILYK-ISVDRGMPWKEACSKAEKLTG-DYEGFYLSNKLRGSQPCVLLAEQGRGR---------NLILYKPNIGKQAHPENLDNLLLRYYKVLPEDAKDVWESQFDFSFTNCSHANWKGKCKQIEEGQECFLGMRLRQYHMLCGALLRVWKRVSDIVSDITNSSILQIVRLKTKQNSKQVGIKIPENCVSRVRAELSRMDEEVKKARREREQFANEQRLRQEMLAKMLNARKLIANPPRSLPNHLNYPRSLLPQTLQPKTEAVSEVLDLTVSPCPSPDIKAPTPNINGVSINVLNSRGRQSGVVPETFDLEDLISQEQQRHRQVVLNSNMRMPSSHSSLNIPQQHVHTLKQNHSSFGVLTQQPNATRSAQYSALLSQLRQGNDKSLMMRILTQMSQKNSSPSQPSHAMLHQNSIPHTSSVHSQLPKRRVNEHVQSQPMQTQPERPSRPKDEFDFDDLDFGYPSPDSQKYPFTSQALPSSTPPPPPYSSSLFAPAPPNSSLSDSSSSSSHFTPSSSSSSEQTHLLPNGHSSMDSLETLDHMIHGAPSDHRQSVIQFKSVDWDAT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V453-1", "uniprot_id": "Q9V453_DROME", "id": "Q9V453-1", "name": "Protein strawberry notch homolog 1", "aln": "MPCKRRTTSARPTARAREIEEEQEVHAKIRSYSRSRATTLKASSEAINRDVSHPTSNKKCETNLNSKNVSQKGQKSQLMTESAGKFDSETKRKRQATVSGSKSQLLDELASDSDNYVKQLRTFLRSTSNTDDEQKRDSPARQSRSRSRRRCTQKNENLDEPDQNTIFKKPEVSSKINLEKHNQRTSTDKEKQYKGQKLNSSIESILNVYDELPSHSDNQALNLSQKRNNAWTTKLPESSPKNIPKKNFDSKSSDLEEAEEKTYLKRQSERNFYSGYRSESEGTNITPAKRSKAQINSIPKLEYSTTYGQAQNLVVSENANITQKPSSDIKSRYRSTEYNQINKPDSQQPINYAHQKEETIDRRREMHMRKEHQYVDNHLNNPAQNKPDRTVSFLEMLSQAEAKKESNQGAKKPTVNKVSNVSQYLIDLGFTAGSPNHDSNSNDGNDEQDNIDRRLNADLDSLFTTDELACPPPPPLAKIPTNLTVERPHSRLSDPKKIESDIDARLQAELDSLPMVAVPADENIEPLGKTDQHFSVPTNKNLSENKAFPKPNQVCIPPQPAIPPQPAIPPAPAYCMANKTMDTGMSSVVQMANNPLASTQHHALPQVPIVTRLKVDQGEDVSVKFTTGLDGLITNVQLLPSTMAMGQPTVKATELESFTAQQLNMLLQSGHPYLSLPMTNSGVPGAVLQETLQTKDAGFPSEQAVEDEEVDYEEIGVADTFAAYWPSKLKFGRAHPDPVVETATLSSVELPNINYQLALPSKTTEC--LSALQLEAVVYACQAHEQILPSGDRAGFLLGDGAGVGKGRTIAGIIFDNYLKGRKRALWVSVSSDLKFDAERDLADIGAHEKIRVATINKFKYSPIDSEENENFKRGVIFCTYTALIGESMTTNSKYKTRFRQLTNWLGKKFEGVIVFDECHKAKNLSLMNVGKSTKTGTTVLDLQKLLPNARVVYASATGASEPRNMAYMVRLGLWGPGTAYPEFYEFVNAVEKRGIGAMEIVAMDMKLRGTYIARQLSFKDVSFRIEEVNMSKEFRKSYNLSAELWADIHKKFQKACRLMCVENRVQKIITCQFWCAHQRFFKNLCIASKVNHVVKMTRQATRMGKAVVIGLQSTGESRTLEHLERHHGKLNSFVSTAKMIIQSFVEKHFPAPKRDSFHHLLNTGEFEPEARSRPPKQKKSKMNTDWVEDDMDAEAGESDIEMYERSCTAAVEKIKSGQKRRGRPPKADKVEKITMQERILEHLCNNMREQDNEDESTNTSDNTKVKVNITERDVERCINMREMLLEKIDVLGRKLPPNTLDKLISELGGTNLVAEMTGRRGRVVRTEYDGYKYEPRCENDSTMDLVNYREKQRFMDGSKHVAIISEAASSGISLQSDKRVSNQRRRLHITLELPWSADRAIQQFGRTHRSNQVNAPEYVFVITDLAGERRFASTVAKRLESLGALTQGDRRATDARDLSQFNIDNSIGRSALENVMQQLTSNKPLDRSQVPQSYKGN---FIYDCCVAMAGVGMINVREENKVKVFTVEKDSNNISKFLNRILGCRVEVQNALFKFFLDKMYSLIMQMKRTGRFDLGILDLDAHGASVKSIKLMRFIRKHATGTAATELHT-VTVERGMSFETALAKYRKEGQYEHEGFYILQKRRQNKNSAILCLQAPSNSSDVSNGKINLQIYRPNTGPQVRLETHASISSRYVKVSPEEAQTYWVQQYELCLNMCSHLYWNRTCPMPTG---CEVGLRMRTYHVLSGLMLPIWDRIELIIVNSG--HKIQIIRMKTDANKKIVGTVVPPAVYDDLVADLS-TDSLVESH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : * . . : . : : . : : . . : :: : . :.: .: *: .:* : . : : . . . .: . . . : .*: :: : **:* ::*:* * *** .:* *** **** ***** *:*.* *::* . ********: **** ** :* .*:*****:***********:**:*.:*.*:***:***.*.*.***:****** ** * * * ::.*:**. :.*. *:*.**:****** : .:::**::*: :* *:************* *** *.:*****. ** **************:** ** ***:** **.: * :*::*:****:***********: * ********..*:*****: : *. ** :* ***: . *::*. : : . :* : ***.:****** ****:**.::*.::: .*.:*********:** * * .:.*:*: *:*:*: :: *:::****: : :. : : ..*.* .* : :. * * . :** : . ::. . .. : *. ... .: . ::: ** :: **::** ****:** .:**.: *:*****:**** . :*.*.*:. ::* ** ***:***.*.* :******:***:***:*:**.*:***:*:************************.****:*:*::********* ************:******::****::*::*. * ** : : . : :: *:.* *. *: * .: .**: .* : : .***.. ::******** .*. ** **::* :.: ** *: *::*:***** . .: . . *: . . . ::. ::*:**: :: * :: ::***: * * .: . :*. * . : :*:** * * : * .: :: :* *:*: * . : :.: *** *: * * *:*:* :::*.* :* :* *: :: : :**:*:**. ..* ** :* : :* * *: ", "identical_positions": 458, "similar_positions": 327, "identity": "21.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100701-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7A6P6-1", "uniprot_id": "F7A6P6_MOUSE", "id": "F7A6P6-1", "name": "Voltage-gated potassium channel regulatory subunit KCNG2", "aln": "---------------------------------------MARLLGHPEAPDAEPGSAGRRGRGGRGARARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDELLRVCDDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEEAAEASAAQPARGPPTSP-----GRALGS---GRLERGRQRLRDVVENPHSGLAGRLFAYVSVAFVAVTAVGLCLSTMPDVRAEEERGECSTKCRNLFVLETVCVAWFSFEFLLRSLQAESKCAFLRTPLAIIDILAILPFYVSLLAG-LAAGP----TGSKMLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTVRRCAREFGLLLLFLCVAMALFAPLVHLAERELGAHRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQRAASPEPALREDSTRDDSTRSAS----------ATEDSSQDPETAG----AAGSLPGRVGP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UJ96-1", "uniprot_id": "KCNG2_HUMAN", "id": "Q9UJ96-1", "name": "Voltage-gated potassium channel regulatory subunit KCNG2", "aln": "-------------------------------------------------MEPWPCSPG----GGGGTRARHVIINVGGCRVRLAWAALARCPLARLERLRACRGHDDLLRVCDDYDVSRDEFFFDRSPCAFRAIVALLRAGKLRLLRGPCALAFRDELAYWGIDEARLERCCLRRLRRREEEAAEARAGPTERGAQGSP-----ARALGPR--GRLQRGRRRLRDVVDNPHSGLAGKLFACVSVSFVAVTAVGLCLSTMPDIRAEEERGECSPKCRSLFVLETVCVAWFSFEFLLRSLQAESKCAFLRAPLNIIDILALLPFYVSLLLG-LAAGP----GGTKLLERAGLVLRLLRALRVLYVMRLARHSLGLRSLGLTMRRCAREFGLLLLFLCVAMALFAPLVHLAERELGARRDFSSVPASYWWAVISMTTVGYGDMVPRSLPGQVVALSSILSGILLMAFPVTSIFHTFSRSYSELKEQQQRAASPEPALQED-----STHSAT----------ATEDSSQGPDSAGLADDSADALWVRAGR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FFQ6-1", "uniprot_id": "E7FFQ6_DANRE", "id": "E7FFQ6-1", "name": "", "aln": "MYQEVAFLAGSTDHQFTSFHFNPLENKHEISSKKGVFYKRAQVQRKATAQEDEVHRNRGAGADEGSLFDRTAIINVGGIRYRIPWSTLEEFPLTRLGRLHNCNNAEEILDLCDDYDARCNEFFFDRSPSAFRSIVTFLAAGKLRLLREMCALSFQEELSYWGVEEASLEWCCLRKLRLRQEEQRERLRLEEEEAELTSPHSCEEAPAVGSPEEGRLSGCMHSLRDMVENPHSGIPGKIFACLSVVFVAITAVTLCVSTMPDLREEEERGECSQRCYNIFVLETVCVGWFSLEFLLRFIQTQSKCTFLRTPLNIIDVVAILPYYITLIVDSMSVGDRPAGSGNNYLEKVGLVLRVLRALRIFYVMRLARHSLGLQTLGLTVRRCTREFGLLLLFLCVAMALFSPLVFLAESELGAKQEFTSIPGSYWWAVISMTTVGYGDMVPRSIPGQVVALSSILSGILLMAFPVTSIFHTFSRSYLELKEEQNRATRHKPDSQDSTKSQNSEDSQDTDSSIHGITETTAVSALHRRSVAVASQGAPQLRRSLKS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . * .****** * *:.*::* . **:** **: *.. :::* :*****. :********.***:**::* ******** ***:*::**:***::** ** ****:** *:** * .. ** . *:*. ***. : ***:*:*****:.*::** :** ***:*** **:*****:* ******** :* .:********.***:***** :*::***:***:** ***::*:**:*::*: . ::.* *.: **:.*****:*****::************::****:***:*****************:***.*** ****:::*:*:*.*********************:******************************** ****:*:**: :* ::. * * :* *: :.. .* * ", "identical_positions": 276, "similar_positions": 102, "identity": "50.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100701-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3V6T2-1", "uniprot_id": "GRDN_HUMAN", "id": "Q3V6T2-1", "name": "Girdin", "aln": "--MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKLE---SQRVNKKVNNDASLRMHNLSILVRQIKFYYQETLQQLIMMSLPNVLIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIERIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTDMS--QEDIEPLLKNMALHLKRLIDERDEHSETIIELSEERDGLHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLENKELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAAEYKKLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTR-SDSSEGFLQLPHQD------SQDSSSVGSNSLEDGQTLGTKKSSMVALKRLPFLRNRPKDKDKMKACYRRSMSMNDLVQSMVLAG-QWTGSTENLEVPDDISTGKRRKELGAMAFSTTAINFSTVNSSAGFRSKQLVNNKDTTSFEDISPQGVSDDSSTGSRVHASRPASLDSGRTSTSNSNNNASLHEVKAGAVNNQSRPQSHSSGEFSLLHDHEAWSSSGSSPIQYLKRQTRSSPVLQHKISETLESR-HHKIKTGSPGSEVVTLQQFLEESNKLTSVQIKSSSQENLLDEVMKSLSVSSDFLGKDKPVSCGLARSVSGKTPGDFYDRRTTKPEFLRPGPRKTEDTYFISSAGKPTPGTQGKIKLVK-----ESSLSRQSKDSNPYATLPRASSVISTAEGTTRRTSIHDFLTKDSRLPISVDSPPAAADSNTTAASNVDKVQESRNSK---------------SRSREQQSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SNZ0-1", "uniprot_id": "GRDN_MOUSE", "id": "Q5SNZ0-1", "name": "Girdin", "aln": "--MENEIFTPLLEQFMTSPLVTWVKTFGPLAAGNGTNLDEYVALVDGVFLNQVMLQINPKSE---SQRVNKKVNNDASLRIHNLSILVKQIKFYYQETLQQLIMMPLPDILIIGKNPFSEQGTEEVKKLLLLLLGCAVQCQKKEEFIEKIQGLDFDTKAAVAAHIQEVTHNQENVFDLQWMEVTDMS--QEDIEPLLKNMVSHLRRLIDERDEHSETIVELSEERDGVHFLPHASSSAQSPCGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQIEVELKRLQQENMNLLSDARSARMYRDELDALREKAVRVDKLESELSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRTSELAEAPQKSLGHEVNELTSSKLLKLEMENQSLTKTVEELRSTADSAAGSTSKILKVEKENQRLNKKVEILENEIIQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETCGKLSKIEFEKRQMKKELELYKEKGERAEELENELNHLGKENELLQKKITNLKITCEKLETLEQENSELERENRKFKKTLDSFKNLTFQLESLEKENSQLDEENLELRRSVESLKCASMRMAQLQLENKELESEKEQLRKGLELMRASFKKTERLEVSYQGLDTENQRLQKALENSNKKIQQLESELQDLEMENQTLQKSLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLFKEINVYKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRHELKTVKKNYEALKQRQDEERMVQSSIPVSGEDDKWGRESQEATRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQQSSLENENESIMKEREDLKSLYDALIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEHKDLEDRYNQLLKQKGQLEDLEKMIKTEQEKMLLESKNHEVVASEYKKLCGENDRLNYTYSQLLKETEILQMDHKNLKSVLNNSKLEQTRLEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKLIKSKKDINRERQKSLTLTPTR-SDSSEGFLQLPHQD------SQDSSSVGSNSLEDGQTLGTKKSSMVALKRLPFLRNRPKDKDKMKACYRRSMSMNDLVQSMVLAGGQWTGSTENLEVPDDISTGKRRKELGAMAFSTTAINFSTVNSSAAFRSKQLVNNKDTTSFEDISPQGISDDSSTGSRVHASRPASLDSGRTSTSNSNNNASLHEVKAGAVNIQSRPQSHSSGDFSLLHDHETWSSSGSSPIQYLKRQTRSSPMLQHKISETIESRAHHKMKAGSPGSEVVTLQQFLEESNKLTSIQLKSSSQENLLDEVMKSLSVSSDFLGKDKPVSCTLARSVSGKTPGDFYDRRTTKPEFLRTGPQKTEDAYTISSAGKPTPSTQGKIKLVK-----ETSVSRQSKDSNPYATLPRASSVISTAEGTTRRTSIHDFLSKDSRLPVSVDSSPPTAGSSSTTASNVNKVQESRNSK---------------SRSREQQSS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PYH7-1", "uniprot_id": "A0A8M9PYH7_DANRE", "id": "A0A8M9PYH7-1", "name": "", "aln": "--MEGEIP-VILEQFMSSSLVTWVKTLGQLGDKEGNVLSEYTELIDGIFLNKVMNQINPEGT---VQGLN-KVNNDIGQRAQNLSVLMYHIKSYYQETLHQMIMIPPPNVLLLGKNPVCEEGLEEIRKLLLLLLGCAVQCERKEEYIEKIQNLDFDTKAEIAAQIQEVTHCQENVFDLHWLEMEGLC--PEEWENLCRSLSVNLKMLVDQRDRQFEAIVELMQGKEMMKSAVFGSDSSLSEPESS--RLPLSQQHLALELTHAKAKIKRLRQELEEKSEQFLDSRQDLDSVEAELKRLQQENMQLLTDARAARMYRDELDTMKERAIRADKLESEVTRYRDKLHNMNFYKAKLEELKEDNQVLMESKAMLEEQLQSIKTRSDKLQPLEKHNLLLEAKLHDMEEERTANRRQIEELMERNVILELSQKRSMEESQRLGWELELAKSPQQNSATELKSLSQEVNEKTCSRLLKLEKENQRLLKALEELQGTCEPLNEFVSQSNHIKGKG-----RTDIVDCETHKSTPAFANMQNG-----------QMTTPTQR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSNQFLDTEHQ--HASLENANGNLPCLEVELHELEAVNQSQFS-------YNHNNAQADIQNQSITHENGYLEQDKSSLEKENRRLRQQVKIQEASLDSSSLKIAVVEKENRTLVKKISNISEACAKYKELEKDNQELIQQAGVDKRMLITLREELLDQRLKLQQKECDVEKYIYELERMRLNQETRMGDHEAVDQGQCKQLESELESSLMKSLKIKKERMATLEARLQESAKINQQLRQDLKTVKQNYEAMLQKDEEEKPGQCSPPER----MWHRESQEATWALLKVKDRVIEVERNNATLQAEKQALQTQLQTLQTQSDGLQAQIIVLQQQTASLQENNTALQTHNAQLQVEKSTVLSQNSSLVAHNTQLQRERHSSEAEREGAVREREDLRTVNELLLRDHERLSVLHERQAAELEVLSHRYSTMESSHRTLEIEHRSLEDRYNTLLQQRAQLEGLEKALREEQKKMQNEICTNRNVTAECQRLRDEKDWLNQTYQKLLVENEGLQLEHKSMKSQLNSIQLEQTQLESELSKLKDLNQQLEISIIKLTNQCELLSQLKGNVEEENRHLLDQIQSLMLQNRTLLDQTMESKDLFHVEQRQYIDKLNELRRQKEKLEEKIMDQYKFYDPSPPRRRGNWITLKMRKLMKTK---SRDQEHVRSSSPQLGSESCEGLDDLRCHDNGSFMGSQGSEESASNSLN-GDTLSPKRSSICALKMFHVKRNKPKDKDKVKSLFRRSLSMNDLLLSEGCLDGDSRQQEDQPEEP----------------------------------TNAISKKHHTSAFHHYSSIDIR--TSIGNQGKETIPSGLTNGTEGQDHGRN-------QSGTNGKSSRAPSASSGEFSVSLENEAWSSD-SSPHPDPFSSNR------QRFNDSP------------------------------------SSSRPN--HEELRQGYCSS---------GSGVGRTSSGRSAG---DRSTPKLDKANIGLYKTQSVQSTESDSKPALDAHGKSSSVSGCLNCFATPMRSPKTGQALSTLPRASCVISTSEGNSRRASVLSTVSGKSVGSVSSKNCKEHQPEPSEEAPKESPVLEEEDHKPDKIFDSAFTIDSVFTNTIFSESS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZT7-1", "uniprot_id": "Q9VZT7_DROME", "id": "Q9VZT7-1", "name": "", "aln": "MAGTATATPMEIDEFVNSSIISWLESCLPR----AELLAGYTSLLDGHIIHSVWLQIDPEPQNNPSELNDLNGKSLSIARAKNFECVVRNLKSFFEEELGQTILVLP-DAFTLGHHPESKNGLEQMKTLLTLLLGAAVQCPNKELFIARIKELDLETQHAIVGLIKQVTDSHSLVLTEDSLERLTPQSMYTHILRLTKERDVMYLKWIDLACVETEMTASDNLVECGQGVSVTRSPSNGTATSTPSSSSNSESNHLAVECADLRSKNRKLRQELEEKSENLLELREELDDKKARFDKLRQESQEWFTEAKRASAYRDEVDILRERAERADRLEVEVQKYREKLGDSDFYKSRVEELREDNRVLLESKEMLEEQLQRYRKRSEHAISLESEIIKYKQKINDMALERDVDRSKLEELLEENSQLQLVARN-LNSTMDLDKSFSEN---EDDCNSGDNSLSEQLTNNAQTRALKLELENRRLTAALEQLK--ESSFHESTSKMLELEKEKKKLSLKIEQMQENINRLTQQNVELEGVFKNALEENKKLQDAVDNRQKSYDRQSLEREADR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QKLSDAEQHVETLNKEKQRIQTLNESIQRRADDLERLAESKTKELEQYLEKSRQYELTKQKLYEIEARVSTYERENASLLKEVSKLKEGSEQKSVQLDDSINRLDVQSKELQKLGKALEDSEQVHQKLVELEKQNQELASQRIIDQEMISTLRNDLVTGTLVTKKVRNNLEKLGLADEEP------------------------------------GELNVEHVVEKLVRNPETFKTVREIMLNVTR-----EQLEEEEREG----------------GVKSDMCVLCHRQEIFTVEKNIELAATPAPAPAQPSSQELRFEHKVRLSPARESAELTRIKDSNTQLQTENARLSVDVAALGSQITSLNTQHVALQLANSQLAAEKDSLLKEIDSLQQEHKHALQDQVTLQCLHDQLSAEYESLNKDKEQLKAAVRDLRQELRDTREQQSALEQRIEELTIQNSNMKTCSEDLSILRTEHSKLTDDFRNLFATSDRFKNEYKNIQEQYKMVRMEHSSLK-------LQNTELSGELNAKSDQVRCLQMEYSKVQQRCEMLIQNNAELDSERKALMDNVSQLLSQYQELLAISLEDKKHFHEEEKNYTERVHSLKRQKEKLEEKIMEHYKKSE----------------------------------------------------------------------------TTVHKKKPFASMLVRRVKKASSDLMNKVPSRNRRSWVDDARTNSQFVIGSESGGNESD------------------------------------------NSNEEPLSIASDTHLLQRNVPLRQSLQRDLLDNSIQRGGAVRS--------------SLQAQKRTDLNNSRRNSVHGSLEAPDVTGSSLTLG-----------------------------------------------------------------------------------------TAGSRRTVYLIDEHQKLPDGSTPGATQSQSVGGSGSVNAAPPTPAEPQTPQK------STENNAPVGPATFLMYNRINTTIGGASNSGDQSPLLQASG-----SVSGTTMQDDKSARKRTEDKSNSIWYEYGCV------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :::*:.*.:::*::: . * *. *:** :::.* **:*: : : : :. * :*:. :: ::* :::* * * *:: : : :*::* .::* *:::.** ****.**** .** :* :*: **::*: :.. *::**. :. *: . :* . * :. :* . * . . * * : :. . :**::* :. ::* ::********:*::*: :::*:. : .:.:*:**. : :::*: * ****:* ::*:* *.*:** *: :*:::* : :***:::***:***:**:*:* ***:**: : **:: **.. : : *::** ** :* ::***:*.* *:: :. ::.: *. .:. .: . : :**..::.: : :: **** **: * ::*:*: .. .*: .:: : : : :: : : . : :. : : . : . . : . : : :. : :: . .:** :: . .:. . : .: . . *::: .* ** :*:: : :.. *:.. :: .** :.* * : .: : ****:*:** .: :* . : ***::*: * :: . ::** *. : .: : :* ...: : :*. : .*.: * ::**: . :: :* ::.:: **:* : * . .. :: . . : . :::.** ***.**:*.*: ::: ** :** ::. * . . *.:. ::* :.*: . ::*: *. **:: ::* * * :::: : *. * :. .:: . * :: :* :. :: .:.: : :: : :.* .* :: *.:: : : :: :*..:* *::*.*..*:. .: : *:: *: ::**:* * :.:::.*.: *:*::. *: * : ** .:*.*. ** *:::* ::::.*:***********::** : * *:..: :: . : .. :*: : *** : * . : . .: .:... :: : . . : .: * . : ..*. .* *: . *: . ** : ..: . *. : * :::.. * . .. . . . :: . . . * . .*. :... ::.: . .:* . . : . : . . ", "identical_positions": 260, "similar_positions": 512, "identity": "13.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100707-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAD3-1", "uniprot_id": "F1MAD3_RAT", "id": "F1MAD3-1", "name": "Polycystin-1", "aln": "MPPG------------APARLALALGLGLWLGALAG-----DPGRGCGPCPLPCFCSPA-PDAACRVNCSGRWLQTLGPSLRIPADATALDLSHNLLQTLDIRLLVNLSGLVELDLSNNRISTLEEGVFAN-----------------------LFNLSEINLSGNPFECNCGLAWLPRWAKEQQVHVVQSEATTCRGPVPLAGRPLLSTPLLDNACGEEYVACLPDNS-SGAVAAVPFFFAHQGPLETAACSAFCFSAGEGLAALSEQNQCLCGAGQPSNTSAACSSWCSSILLSFNSACGGPTLLQHTFPASPGAALVGPHGPLASGQPADFHINSPLPISSTCWNFGDGSPEVDMAGP--AATHSYVLPGGYHVTVVLTLGAGSALLETEVQVEVAPTVLELVCPSFVHSDESLD--LGIRHRGGSALEVTYSILALDKEPAQVVHPLCPSDTEIFPGNGHCYRLVAEKAPWLQAQEQCRTWAGAALAMVDSPAIQHFLVSKVTRSLDVWIGFSSVEGKE-GLDPQGEAFSLESCQNWLPGEPHPATEEHCVRLGPAGQCNTDLCSAPHSYVCELRPGGPVGDADNFLLGVSGGGRSGPLQP--LAQQGTLQGPLQPVEVMVFPGLSPSQEAFLTAAEFETQELEDPVQLRLQVYRHSR-------------EAVAPEGSSEL-----DNSTEPAPKCVPEELWCPGANVCVPFDALCNSHVCINGSASRL---GLPRASYTLWKEFFFSVPAGPPTQYLVTLHGQDVPMLPGDLVALQHDAGPGTFLHCPLASSCPG-QALYLSTNASDWMT--NLPVHLEEAWAG-PVCSLQLLLVTEQLTPLLGLGSNPGLQHPGHYEVRATVGNSISRQNLSCSFSVVSPVAGLRVIHPIPLDGHIYVPTNGSILVLQVDSGANATATAHWFGGNVSAPFEDACPPEVDFLKQDCTEEA--NGTLFSVLVLPRLKE-GDHTVEIVAQNGASQANLSLRVTAEEPICGLRAVPSPEARVLQGILVRYSPMVEAGSDVAFRWTIDDKQSLTFHNTVFNVIYQTAAVFKLSLTASNHVSNITVNYNVTVERMNKMHGLWVSAVPAVLPPNATLALTGGVLVDSAVEVAFLWNFGDGEQVLRQFKPPYDESFQVPDPTVAQVLVEHNTTHIYNTPGEYNLTVTVSNTYENLTQQVPVSVRTVLPNVTIGMSSNVLLAGQPITFFPYPLPSADGVLYTWDFGDGSPVLIQSQPVLNHTYSMTGTYRISLEVNNTVSSVAAHVDICVFQELHGLTVYLNQSVEQGAPMVVNASVESGDNITWTFDMGDGTVFTGPEATVEHVYLRAQNFTVTVGATSPAGHLSQSLHVQVFVLEVLRIEPSTCIPTQPSAQIMAHVTGDPAHYLFDWTFGDGSSNVTVHGHPSVTHNFTRSGIFPLALVLSSHVNKAHYFTSICVEPEICNVTLQPERQVVKLGDEAWLVAYPWPPFPYRYTWDFGTEDSIHTQTGGSEVTFIYREPGSYLVIVTVSNNISSTNDSAFVDVQEPVSVTGIRING--SHVLELQQPYLFSAMGNGSPAAYLWELGDGSQHEGPEVTHIYSSTGDFTVRVSGWNEVSRSEAQLNITVKQRVRGLTINASRTVVPLNGSVSFSTLLEVGSDVHYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSAQDSIFIYVLQLIEGLQVVGGD--GGCCFPTNYTLQLQAAVRDGTNISYSWTAQQDG-GPTLISSGKSFSLTALKASTYYVHLRATNMLGSASANRTIDFVEPVESLILSASPNPAAVNTSLTLGAELAGGSGVVYTWYLEEGLSRETSMPSTTHTFAAPGLHLVRVTAENQLGSVNATIEVAVQAPVGGLSIRTSEPDSIFVAAGSTVPFWGQLAEGTNVTWCWTLPGGS-KYSQYIDVRFPAAGHFSLWLNASNAVSWVSAVYNLTVEEPIMNLVLWASSKVVAPGQPVHFQILLAAGSAVTFRLQVGGSIPEVLPSLHFSHSFFRVGDHMVSVQAENHVSRAQAQVRILVLEAIVGLQVPNCCEPGMATGTEKNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGILEIHVRAFNELGGVNLTLVVEVQDIIQYVTLQSGR--CFTNRSARFEAATSPSPRRVTYHWDFGDGTPVQETEESWTDHYYLHPGDYRVEVNATNLVSFFVAQATVTVQVLACREPEVEVALPLQVLMRRSQRNYLEAHVDLRNCVSYQTEYRWEVYRTTSCQRPGR----MTQMVLP-GVDVSRPQLVVPRLALPVGHYCFVFVVSFGDTPLARSIQANVTVAAERLVPIIEGGSYRVWSDTQDLVLDGSKSYDPNLEDGDQTPLNFHWACVASTQSETGGCVLNFGPRGSS-VVTIPLERLEAGVEYTFNLIVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGHCHNCSSGSKQGRWAARTFSNKTLMLNENTTSTGSTGMHLVVRPGALHDGEGYIFTLTVLGHSGEEEGCASIRLLPNRPPLGGSCRLFPLES---VRGLTTKVHFECTGWRDAEDGGAPLVYALRLKRCHQNYCEDFCIYKGSLSTYGAVLPPGFQ-PLFVVSLTVVVEDQLGASVVALNRSLTIVLPEPSGNPADLIPWLHSLTASVLPGLLRQADPQHVIEYSLALITVLNEYEQAPDMVSEPN--LEQQLRAQMRKNITETLISLRVNTVDDIQQITAALAQCMVSSRELMCRSCLKKMLQKLEGMMRILQAETTEGTLTPTTIADSILNITGDLIHLASLDMQGPQP---------------LELGAEPPSLMVASKAYNLSSALMCILMRSRVLNEEPLTLAGEEIVALGKRADPLSLLCYGKAWGPSCH-FSIPEAFS--------GALSDLSD--VVQLILLVDSNPFPFGYISNYTVSTKVASMAFQTQTGTQIPIEQLAAERAITVKVPNNSDQ--AAQ---SSHSPVGSTIVQPRASVSAVVTADNSNPQAGLHLRITYTVLNARYLSEEREPYLAVYLHSVSQPNEYNCSASRRISLEVLEG--ADHRPYTFFIAPGTGTLGRSYYLNLTS---HFHWSALEVSVGLYTSLCQYFSEEAMMWRTEGIVPLEETSPSQAVCLTRHLTAFGASLFVPPSHVQFIFPEPSVSINYIVLLTCVICLVTYVIMAMILRKLDQLDVSRVRVIPFCGKGGRFKYEILVKTGWSRGSGTTAHVGIMLYGEDNRSGHRHLDGDRAFHRNSLDIFQIATPQSLGSVWKIRVWHDNKGLSPAWFLQHIIVRDLQSARSTFFLVNDWLSVETEANGGLVEKEVLAANEAALWQFQRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRVQRVTCCVLLLCLFLAANAVWYGVVGDTTYSMGPVSSLMSPSVDTVAIGLVSSVVVYPVYLAVLFLFRMSRSKVSGDQNPTPTGQQALDVDSYLDPSVLDSSLLTLSGLT--EAFSGQVKNDLFLEDAKSLVCWPSSEGTLSWPDLLSDPSVMS--STLQRLAQGRPGCMLG------SEEDGASLVSPSLPAKYLSASDEDLIHQVLADGANNPDPTQDALIERDLLTSLSSAPGEKTETLILQTMGEKRPPSMGLTWEQSPVTRLSRTGLVEGLRKRLLPTWCAPLAHGLSLLLVAVAVAVSGWIGASFPPSVSVMWLLSSSSSFLASFLGWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSERVPRVRPPHGFALFLAKEEARKVKRLHDMLKSLLVYMLFLLVTLLANYGDASCHGHAYRLQSAIKQELDSQAFLAITRSDEFWPWMSHVLLPYVHGNQSSPELGPPRLRQVRLQEAFCPDPSSS-EHMCSATGSLSTSDYGIGWQSVVQNGSETWAYSAPDLLGAWYWGYCAVYDSGGYIQELGLSLEESRARLGFLQLHNWLDSRSRAVFVELTRYSPAVGLHAAVTLRLEFPVAGHALAAFSVRPFALRRLSTGLSLPLLTSVCLLLFALYFSVAEVHTWRREGCARTARPEAWARWLLVMLTAATGLVRLAQLGIADRQWTRFVHDHPHHFTSFDQVAQLGSVARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELMGATLGLVLLGVAYAQMAILLISSGADTLYSMARAFLVLCP--GARVPTLCPSESWYLSP----LLCVGLWALRVWGALRLGAVLLRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWMGFSKVKEFRHKVRFEGMDPLPSRSSRGSKSSPVVPPPSA-------------GSEASHPSTSSS-----QPDGLSAGLG------------RSALRLEPEPSRLHAVFESLLVQFDRLNQATEDVYQLEQQLQSLRGHGHSGPPS----------------------------------------------------------------------------------------------------------------------------------------------------------------SPSPGGFPASQPALPSRLARAS-------------------------QGPDQTTGPSR----VSLWPNNKVHPSST---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08852-1", "uniprot_id": "PKD1_MOUSE", "id": "O08852-1", "name": "Polycystin-1", "aln": "MPLG------------APALLALALGLGLWLGALAG-----DPGRGCGPCPLPCFCGPA-PDAACRVNCSGRWLQTLGPSLRIPADATALDLSHNLLQTLDIGLLVNLSALVELDLSNNRISTLEEGVFAN-----------------------LFNLSEINLSGNPFECNCGLAWLPRWAKEHQVHVVQSEATTCRGPIPLAGQPLLSIPLLDNACGEEYVACLPDNS-SGAVAAVPFYFAHEGPLETEACSAFCFSAGEGLAALSEQNQCLCGAGQASNSSAACSSWCSSISLSLNSACGGPTLLQHTFPASPGATLVGPHGPLASGQPADFHITSSLPISSTRWNFGDGSPEVDMASP--AATHFYVLPGSYHMTVVLALGAGSALLETEVQVEATPTVLELVCPSFVHSNESLE--LGIRHRGGSALEVTYSILALDKEPAQVVHPLCPLDTEIFPGNGHCYRLVAEKAPWLQAQEQCRTWAGAALAMVDSPAIQHFLVSKVTRSLDVWIGFSSVEGTE-GLDPRGEAFSLESCQNWLPGEPHPATAEHCVRLGPAGQCNTDLCSAPHSYVCELRPGGPVWDTENFVMGMSGGGLSGPLHP--LAQQETVQGPLRPVEVMVFPGLSPSREAFLTAAEFSTQKLEEPAQMRLQVYRPSGG------------AAAVPEGSSEP-----DNRTEPAPKCVPEELWCPGANVCIPFDASCNSHVCINGSVSRL---GLSRASYTLWKEFFFSVPAGPPTQYLVTLHSQDVPMLPGDLIGLQHDAGPGTLLQCPLASSCPG-QALYLSTNASDWMT--NLPVHLEEAWAG-PVCSLQLLLVTERLTPLLGLGPNPGLQHPGHYEVRATVGNSVSRQNLSCSFSVVSPIAGLRVIHPIPLDGHIYVPTNGSVLVLQVDSGANATATAQWFGGNISAPFEDACPPEVDFLKQDCTEEA--NGTLFSVLMLPRLKE-GDHTVEIVAQNGASQANLSLRVTAEEPICGLRAVPSPEARVLQGILVRYSPMVEAGSDVAFRWTIDDKQSLTFHNTVFNVIYQSAAIFKLSLTASNHVSNITVNYNVTVERMNKMHGLWVSAVPTVLPPNATLALTGGVLVDSAVEVAFLWNFGDGEQVLRQFKPPYDESFQVPDPTVAQVLVEHNTTHIYTTPGEYNLTVLVSNTYENLTQQVTVSVRTVLPNVAIGMSSNVLVAGQPITFSPYPLPSTDGVLYTWDFGDGSPVLIQSQPVLNHTYSMTGAYRITLEVNNTVSSVTAHADIRVFQELHGLTVYLSPSVEQGAPMVVSASVESGDNITWTFDMGDGTVFTGPEATVQHVYLRAQNFTVTVEAANPAGHLSQSLHVQVFVLEVLHIEPSTCIPTQPSAQLMAHVTGDPVHYLFDWTFGDGSSNVTVHGHPSVTHNFTRSGIFPLALVLSSHVNKAHYFTSICVEPEIRNITLQPERQFVKLGDEARLVAYSWPPFPYRYTWDFGTEDTTHTQTGGSEVKFIYREPGSYLVIVTVSNNISSTNDSAFVEVQEPVLVTGIRING--SHVLELQQPYLLSAMGSGSPATYLWELGDGSQSEGPEVTHIYSSTGDFTVRVSGWNEVSRSEAQLNITVKQRVRGLTINASRTVVPLNGSVSFSTLLEVGSDVHYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSAQDSIFIYVLQFIEGLQVAGGD--NGCCFPTNYTLQLQAAVRDGTNISYSWTAQQEGSLITLFGSGKCFSLTSLKASTYYVHLRATNMLGSAAANRTIDFVEPVESLILSASPNPAAVNMSLTLCAELAGGSGVVYTWYLEEGLSWKTSMPSTTHTFAAPGLHLVRVTAENQLGSVNATVEVAIQVPVGGLSIRTSEPDSIFVAAGSTLPFWGQLAEGTNVTWCWTLPGGS-KDSQYIAVRFSTAGSFSLQLNASNAVSWVSAMYNLTVEEPIVNLMLWASSKVVAPGQPVHFEILLAAGSALTFRLQVGGSVPEVLPSPHFSHSFFRVGDHLVNVQAENHVSHAQAQVRILVLEAVVGLQVPNCCEPGMATGTEKNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIHVRAFNELGGVNLTLMVEVQDIIQYVTLQSGR--CFTNRSARFEAATSPSPRRVTYHWDFGDGTPVQKTEEFWADHYYLRPGDYHVEVNATNLVSFFVAQATVTVQVLACREPEVEVALPLQVLMRRSQRNYLEAHVDLRNCVSYQTEYRWEIYRTASCQRPGR----MAQMVLP-GVDVSRPQLVVPRLALPVGHYCFVFVVSFGDTPLARSIQANVTVAAERLVPIIEGGSYRVWSDTQDLVLDGSKSYDPNLEDGDQTPLNFHWACVASTQSETGGCVLNFGPRGSS-VVTIPLERLEAGVEYTFNLIVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGHCHNCSRGYKQGCWAARTFSNKTLVLNETTTSTGSTGMNLVVRPGALRDGEGYIFTLTVLGHSGEEEGCASIRLSPNRPPLGGSCRLFPLDS---VRGLTTKVHFECTGWRDAEDGGAPLVYALLLKRCRQSYCENFCIYKGSLSTYGAVLPPGFQ-PLFVVSLAVVVQDQLGAAVVALNRSLTIVLPEPSGNPADLVPWLHSLTASVLPGLLKQADPQHVIEYSLALITVLNEYEQAPD-VSEPN--VEQQLRAQMRKNITETLISLRVNTVDDIQQITAALAQCMVSSRELMCRSCLKKMLQKLEGMMRILQAETTEGTLTPTTIADSILNITGDLIHLASLDMQGPQP---------------LELGVEPPSLMVASKAYNLSSALMRILMRSRVLNEEPLTLAGEEIVALGKRSDPLSLLCYGKALGPSCH-FSIPEAFS--------GALSNLSD--VVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQTGTQIPIEQLAAERAITVKVPNNSDQ--AAQ---SSHNPVGSTIVQPQTSVSAVVTADNSNPQAGLHLRITYTVLNERYLSAEPEPYLAVYLHSVSQPNEYNCSASRRISLEVLEG--ADHRLYTFFIAPGTGTLDRSYYLNLTS---HFHWSALEVSVGLYTSLCQYFSEEMMMWRTEGIVPLEETSPSQAVCLTRHLTAFGASLFVPPSHVQFIFPEPSASINYIVLLTCVICLVTYVVMAMILRKLDQLDVSRVRVIPFCGKGGRFKYEILVKTGWSRGSGTTAHVGIMLYGEDNRSGHRHLDGDRAFHRNSLDIFQIATPHSLGSVWKIRVWHDNKGLSPAWFLQHIIVRDLQSARSTFFLVNDWLSVETEANGGLVEKEVLAANEAALWQFQRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRVQRVTCCVLLLCLFLAANAVWYGVVRDTTYSMGPVSSLISPGVDTVAIGLVSSVVVYPVYLAVLFLFRMSRSKVSGDQNPTPTGQQALDVDSYLDPSVLDSSLLTLSGLT--EAFAGQVKNDLFLEDAKSLVCWPSSEGTLSWPDLLSDPSVVS--STLQRLTQGRPGCMLG------SEEDGASLVSPSLPAKYLSASDEDLIHQVLADGANNLVPTQDTLLETDLLTSLSSVPGEKTETLILQTVGEERPASMGLSWEQSPVTRLSRTGLVEGFQKRLLPAWCAPLAHGLSLLLVAVAVAVSGWIGASFPPSVSVMWLLSSSSSFLASFLGWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSERVPRVRPPHGFALFLAKEEARKVKRLHDMLKRLLVYMLFLLVTLLANYGDASCHGHAYRLQSAIKQELDSQAFLAITRSDEFWPWMSHVFLPYVHGNQSSPELGPPRLRQVRLQEAFCPDPSSS-EHMCSAAGSLSTSDYGIGWQSVVQNGSETWAYSAPDLLGAWYWGYCAVYDSGGYIQELGLSLEESRARLGFLQLHNWLDSRSRAVFVELTRYSPAVGLHAAVTLRLEFPVAGHALAAFSVRPFALRRLSTGLSLPLLTSVCLLLFALYFSMAEVQTWRKDGCACTARPDTWARCLLVILTAATGLVRLAQLGIADRQWTHFVQDHPRHFTSFDQVAQLGSVARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELMGATLGLVLLGVAYAQMAILLISSGADTLYNMARAFLVLCP--GARVPTLCPSESWYLSP----LLCVGLWALRVWGALRLGAILLRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWMGFSKVKEFRHKVRFEGMDPLPSRSSRGSKSSPVVLPPSS-------------GSEASHPSTSSS-----QPDGPSASLS------------RSTLKLEPEPSRLHAVFESLLVQFDRLNQATEDVYQLEQQLQSLQGHGHNGPPS----------------------------------------------------------------------------------------------------------------------------------------------------------------SPSPGCFPGSQPALPSRLSRAS-------------------------QGLDQTVGPNR----VSLWPNNKVHPSST---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P98161-1", "uniprot_id": "PKD1_HUMAN", "id": "P98161-1", "name": "Polycystin-1", "aln": "MPPA------------APARLALALGLGLWLGALAG-----GPGRGCGPCEPPCLCGPA-PGAACRVNCSGRGLRTLGPALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFAN-----------------------LFNLSEINLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEYVACLPDNS-SGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSASFACLSLCSGPPPPPAPTCRGPTLLQHVFPASPGATLVGPHGPLASGQLAAFHIAAPLPVTATRWDFGDGSAEVDAAGP--AASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPAALELVCPSSVQSDESLD--LSIQNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGNGHCYRLVVEKAAWLQAQEQCQAWAGAALAMVDSPAVQRFLVSRVTRSLDVWIGFSTVQGVEVGPAPQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELQPGGPVQDAENLLVGAPSGDLQGPLTP--LAQQDGLSAPHEPVEVMVFPGLRLSREAFLTTAEFGTQELRRPAQLRLQVYRLLS-------------TAGTPENGSEPESRSPDNRTQLAPACMPGGRWCPGANICLPLDASCHPQACANGCTSGP---GLPGAPYALWREFLFSVPAGPPAQYSVTLHGQDVLMLPGDLVGLQHDAGPGALLHCSPAPGHPGPRAPYLSANASSWLP--HLPAQLEGTWAC-PACALRLLAATEQLTVLLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAPRDGRLYVPTNGSALVLQVDSGANATATARWPGGSVSARFENVCPALVATFVPGCPWET--NDTLFSVVALPWLSE-GEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYSPVVEAGSDMVFRWTINDKQSLTFQNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQGLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDPSVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVAGRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGAAAQADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDGTVLSGPEATVEHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQPDARLTAYVTGNPAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEVGNVTLQPERQFVQLGDEAWLVACAWPPFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGSYLVTVTASNNISAANDSALVEVQEPVLVTSIKVNG--SLGLELQQPYLFSAVGRGRPASYLWDLGDGGWLEGPEVTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVVPLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSAQDSIFVYVLQLIEGLQVVGG----GRYFPTNHTVQLQAVVRDGTNVSYSWTAWRDR-GPALAGSGKGFSLTVLEAGTYHVQLRATNMLGSAWADCTMDFVEPVGWLMVAASPNPAAVNTSVTLSAELAGGSGVVYTWSLEEGLSWETSEPFTTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQVPVSGLSIRASEPGGSFVAAGSSVPFWGQLATGTNVSWCWAVPGGSSKRGPHVTMVFPDAGTFSIRLNASNAVSWVSATYNLTAEEPIVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFRLQVGGANPEVLPGPRFSHSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCCEPGIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQVRAFNALGSENRTLVLEVQDAVQYVALQSGP--CFTNRSAQFEAATSPSPRRVAYHWDFGDGSPGQDTDEPRAEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVLMRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGR----PARVALP-GVDVSRPRLVLPRLALPVGHYCFVFVVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRDLVLDGSESYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFGPRGSS-TVTIPRERLAAGVEYTFSLTVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGSKRGRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGCASIRLSPNRPPLGGSCRLFPLGA---VHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQGHCEEFCVYKGSLSSYGAVLPPGFR-PHFEVGLAVVVQDQLGAAVVALNRSLAITLPEPNGSATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPK--HERQHRAQIRKNITETLVSLRVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQAETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQP---------------SELGAESPSRMVASQAYNLTSALMRILMRSRVLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCH-FSIPEAFS--------GALANLSD--VVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNSDW--AARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEPYLAVYLHSEPRPNEHNCSASRRIRPESLQG--ADHRPYTFFISPGSRDPAGSYHLNLSS---HFRWSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFVPPSHVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAIPFCGQRGRFKYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRAFHRNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSPSPTPAGQQVLDIDSCLDSSVLDSSFLTFSGLHAEQAFVGQMKSDLFLDDSKSLVCWPSGEGTLSWPDLLSDPSIVG--SNLRQLARGQAGHGLG------PEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETDLLSSLSSTPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSARVPRVRPPHGFALFLAKEEARKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSRAFLAITRSEELWPWMAHVLLPYVHGNQSSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSDYDVGWESP-HNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLHNWLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPLLTSVCLLLFAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAADRQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLGLVVLGVAYAQLAILLVSSCVDSLWSVAQALLVLCP--GTGLSTLCPAESWHLSP----LLCVGLWALRLWGALRLGAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWMGLSKVKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSA-------------GSDASHPSTSSS-----QLDGLSVSLG------------RLGTRCEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQQLHSLQGRRSSRAPA----------------------------------------------------------------------------------------------------------------------------------------------------------------GSSRGPSPGLRPALPSRLARAS-------------------------RGVDLATGPSR----TPLRAKNKVHPSST---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QBN4-1", "uniprot_id": "A0A8M9QBN4_DANRE", "id": "A0A8M9QBN4-1", "name": "", "aln": "MPCGNGQIASKRKHGVCLPKFGLFSSLLFALCCLEARSVVKADAAACTPCPGNCSCTAAGPQNSCVVNCSNIGLDQAPAASDLPADTHTLDLSRNRIHSVDWSLFDHLTALKELYLQSNRLATLPHGIFGCGPLAVLDLSNNQITTIEERTCDHLFNLTTIDLSFNPFLCDCKLVRLVSWLQEQGVKVKRPNSMLCDRPPEVRNQPLLNVSVHT--CGLTYAGCLQDEAHTAGVELVIFSSSTPGPFSREECNSKCFHENQRYGGLGQQRECLCSTNSEPNHISESQCSAACSDPLVMKECR-WTVARDVFQVNFSASLPSRRVSVHS--EAVLSVASSVSPASFSWDFGDLSPRVNTSTPNTTARHKYGVPGRYQAHVSLSAGHQEIMAQGSVSVELPP-RLELHCPDLIVANQSLEAELSLVNWGGVGVTVDWRISKDGREVAR-AEPQCPPDALHHVDSSRCFLLVSEEVSWAEARRNCSGRG-GELAVVHSQSLRDLLATKITQERGVWLGLSDQSSPHVLRWLDGSDVLPGEEGSRDRGSLQPG--NVCVSLDGGAQPSIHSCTAKRAFICQFTRHVRVPDAGVSMVGTAVFNTHNPLRSPAVSHTSVPNTPARRVELLLFAGLSFVSAGRLSSLEFVTHSLDTHTQVRFQVYRPRCPSFTHTLLPACGELCAPISVCQAPDEWMNSTEAPAAPGCPAERHFCPFSERCVSLSSPCPSSACFNCSGVSPPPAGTQYPEYSLLDEVLISLPAGPAASVLVQEEVQDLLVSPGDIIALQHDAGPSGLLQCSPDPSSPWSQSLLIQNRSHWWDANETLQADVEGVWEEGVLCQIRVLYVGQNQTGLQGPFLRSGLPQVGDYSLEVTSNDEDFPVTASCPIQVIPPLT-PTVIHPTNHNNTVYFLPNQTWVLIKVRS--QHSALIGCQGNNLTVAFERACPQSLLSKVAECRQSDPFNDTMFAWVDLQAGSTPGQTTVVLHVKSEVTEAYLQIQARVQEPLRGLLIQPHPAHRVLMESVVCYTPSVEAGTDPSFRWTVDDKPHFTYYNSMLNIIYQNAAVYKLTVTAMNQVSMLTEDFNVTVDRMNPMTDPTVHGVPKIVQQGSLLNLTAFITIDTAVDVTFWWWFGDGGNRTHQFKSPYDD-----NPSTNMVGIRDHVEYIYAQPGEYTLLLSTSNRYENKTCKVDVYVFSILTSVQIEVYPPLLRAEKPADFEAHPLPSPYGIIYTWNFGDNSSIQQGRERRVPHAYTHSGIYNICVNVNNSISSTDTCANIIVYEDIKGLEVMSSAPTEHNTPTVIRASLEAGNNVTWSFDMGDGKVHKSVEPQIKYKYREDGNYTVNVTAENAVSSQWLTIPVEVFVLQVLSLEPTGCIEENKIVSFHVFVSGNASGHQYVWSFGDGSPNETQYGTPLITHSYVNSGDYNLSLLVSSDANKAHFYTRICVQPKVTVVSVTPLRTHVRLGEESRFTVAAVPEFNYTYLWDFGVVDSGGPVRGGKEMTYTFNSAGEYQVTVTVQNNISSINASVSIEIQQSVGLLLISHNGDKGNHLSLHQEYNFKASSDSMNAVYIWDFGDGTQCNGKIVSHSYNSSGRFSISVIGKNEVSKTKNETSVVVLAPITRLSINASLVNVPLNASVHFEAQLDQGDDVRYSWILCDRCKSIQGTHTMFYTFLSVGTFNVIVTAENAISMAQSSIFIFVQRELEGLQIVADDLIEGCCFATNRILHLQASLKEGTNMTFTWNLLREHENHDNLT-GKTIELNFSTPGPCEVILKATNLLGQLSVNKTIEFLDPVQDLVLESLPNPAAVNAMTNMTVSVNSGTNLHYKWWADGDL-LESDMPSILHRFRSAGLKLVKVEVSNKVNSEVVSKWISIQEPISGLTFIAKNVTENFVATGDNVSMRGDTQMGTNISWMWLLPDSTKSNQRAISYIFHTPGLFTVALNATNDVSGEMYLRDFTVQDRIQGLELKASKQIAAVGENVEFTISVSSGTSVSFILSISGDATVVLNNLTYVHQFTSVAKYYVNLTAYNHVSSERRTLHIEVMEPVTKLTILDCCDAAIPVGVPRSYVASTPTREPLTILWTFDLHHG---FKISRVGKSMTYAPEQPGNLTIFLRAFNSLNGLNVTKVIQVQSIIRSALLDAQPSDTFVNKTVNFHVGITPASTPATYQWDFGDGTSGTITTAPFHNHVYLIPGHYVVRVNVSNLVSWVTAQIEVNISVLKCDEPEVQIIQAPRLAIWRHQPTLVEASVNLKGCVLYGVEYLWEILTSPRCQDDDKKGPPPSKIQLPPEVNVRRLQLSVPKISIPAGNYTLVFSLSYEGVPLRKAACLQLSVMSKKLVPIIEGGTYRVWSKTHDLDLSAEQSYDPNLDPENQVPLSYHWECVSTSKGPDHCSTLHFGLGPSDPVLGISGSELEVDVEYTFRLTVSKDGMAPESTTQTVCVQSGRIPMVSLKCVSCKAQSRYEISQSSYVYLAGHCSNCQS-SHRGRWTAMTRRNETLVLDLNTTTTGSDSMRLVLRQGILRDRESYIFSLHVTDDGMDREGVAYIELHPNLPPDGGACSLWADGGGTQVQTLLERVHFNCSGYTDLDETESPLVYSLLVVRCSELYCEEFYVYKGTSPEHSAFLPPGFSSAQYRVSVLVMVEDHQGASILARNTSMEVVLPVVPDGFVSLPHWLSNVTASTLRELLRQGDSQRVRELSLALITVLNEYEQGVSRRRERVSKSERQYRVSIRGNITRALTSLDLTTVSDIQQTSAALAQCTAVSREFVCEECQNSTLDKLESMLEILQTDTKQGTVTPTEIADNILNIMGDLIHQVNQVASSPPPEAEDQDGSVSQQPPFLQEELQHHPLRVAAKAYTLSSVLMRILMLGRVLNEEPLILRGAEIAAVGKRADPQSLLCYGESDAPECQGFSIPRPFNSSLGRAAEGALAPNSDDGIVQLLFQVEPNPFPFNYVDNYPVSTEVASMEFRTVNGTQIPIADLDESQAITVAVNNGSATGLDASGLKAVLPPAGAVNISRCDSIIVRVNTRNTNRQAGVYIQLNFTVLDD-----TPDSWITAYLDTSEWPNEFNSTDRKRITLNMTRRPDLHHRDYTFFLSPNVYDTTQDHFINVSSGCGTAEPELLRLEVAVFTSLCQYFSESAKQWRTDGMEPLAETSVGQAVCRTHHLTAFAASLFVPPDAVSFIIPERSVSRSVVVVLVCVVSLLCYAVAGAVLRKLDQMDLRRASVVPLCGKDGLYKYEIQLKTGWSPGAGTTAHVGISLHGSEGRSGHRHLDSVGAFARNSLDIFHIASDSSLGSVLKIRLWHDNKGLSPAWLLQYVLVKDLQTGSSFFFLIEEWLSVDNEKTDGRVEIEVEASEELYLRDWPRLLRWELQRAVCESHVWLSLWERPSRSPFTRLQRLTCCSLLLHLQMLAAAVWYGTVS-YKHSSVPVADLVSVNVETLWAGMVSCLLVYPLYLLVFCLFRLSRSKVSVEQLPPQVDQESLEIDDFLENSLTGSSFLMLNAIPG-ETYSEETNIDLPTPSTKSLQRWSMPD--CDWPDVLTDPSVEMGPVFPPRLKRGQGSRHLGVDITFSPDHEDDTVCQNSHRNKYFSSSDEDLIKRILADGQLLSQTDSD-------VGDLSSIFGDKTEVILLQKMNEPVP-CATFRRDPPKTAFTSRTVVADVCKPRPLPPLCGLAALWASWAGLILSSSLSMWLGRGFSEGVALMWLISCIVSFLSSFLLLEPLKVLLEGVYFSLVVRRLRPEEQDVLVECPRVERVVQRIPRVRPPQGFALSQAREEARKVRLLHTMLKGFLLYMLFLMVVLLLNYSDSEKDAHRLRLNAQLQDHFLTKHFNNISSREDVWAWLSNSLLPRLLDEQVLMEKTGSLLIGRARLRQTRAQPECPVSGYFPASSWFG--CVQAGWAESASGLVQNWSVSTAQSSGVWHWGQVSVYSSSGFVQDLSRKMQDSKNLINQLNTHQWLDPLTRALFLEFSLYNINTDLLSVFSFLLEFPVSERAQLSLDLKTFSLHTLSHGMDLPLFLTLILLVLLIYFSVREGLLVWKQGRCYFLRVWNLASVCSLLLAVCVASLHLSRSVVSAQQWRAFLQHR-DAFTDFFPLAQQNQLLTQMSATLLFLLVLKASHQLRFLREWGVFGRTLRKSFWELLMVAVTLLVFLLAYSHTGHLLFHSVMEGYGTVSSTCFKLIGSSGRGLLSWRPDSGSFPCSGSCFIFYISFTLLRLVLLWILMSALLRN-YRRARAELYRPAVDLQDYEMVELFLRRLKMWMGLSRTKEFRHKVRFEGMELPPSRSSSTSDCKSLCLPPLDTPEAPPTPDSVDGGSEASWRPTSSSPCSLAEVPGLGLGLSSGLGVIVGGQGWKERAEMEATLRRVLPAFDALLLQLDRVTHATEDLYRTEYRIERLLRKSRGQERARSRSRRSLDNAGQRRHKHRSTEVSESSRSPLRTEISDRNLHKSDRRSRKTDSRKFSKITSVLSKSLNKGDSSPHRENSLQRTQEKPCTKVEDVRNTEKEPSMVNSDPLQASSLELDRIPPRAQKAEKISQKVKRSSNKVDPNFQKDSEVDGCAIKPAQTPAPTPVPVPASAPSTAPVFAITTPVPIPRPHEWVPPSSSENLPTSVFRHPAHTTTNPTRKRKHKPPALKNKVHPNTDRPISGHPKP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . . . :.* .* : * .* . . .* ** * * .* * :* ****. * .: :***: :**:*:* ::::* *: :*:.* ** :..*:::** .*:*. ****: *:** *** *:* *. * * :*: *:* :.:: * * : .:***. .: ** *..** *:: :. * * * : * :. *.: ** .: ..*.:* ***.: . .. . . .: * *: :..* .. .*:* . : .: * * : : :.:. :: *:*** *..*: : * :* * * :** *: . *: * . : .*.** .* *** **. : :::**: *.: : ** .: . : * ..* *: ..* ** *: . ...:*: ** *:..* :*:.:* . . **:*.* ::: :*.:::*:. .**:*:* .. . *. . . . *. :*. : ** *. . . . *:* ::::*:: * *: ::* . . .** . ::: . * . **:::*.** . *:: ** *:.* .*:*:**** . . . .. : ** * . :** :: *:.:.: * . .* * . * . *:* *.::*:****.:. * . **: : ***::.*******. :*:*. .. * :: :. .: * . * ..:* .* * :::* . :. * * * ..** * *.:.. .: . **.:.*:.*:: **:* :. :*. .* : ::::* * : :* *..::. ** .** : * . *.*:*: : * . *: .* : .:. .:.* *.::. .:**: ** * * *** :* *:* ****:* ****::** :*: * ::*:***.**::**::** *:** :* ::****:*** * . * ** :: .: * **. : :*:**:*:* * **** : :**:.**:: :*:. * :..:. : * **** * : .** :** * :* * * : *..* : : :* * :* * .:****. *::***:***.*.: : *:*: * *.: ::***::*.. : .:: *:::::** * . ..*:.:* *: *::::*:*:**:******.* .. *. ::: * . * **.* * .... :: * ****:** :**: ** : . : ..*:*:. : : *:*****.* * * * :**.:..** : *:*::** .*:**::* ***:*:: ::: * * *:**:*: :.. . * * * * ****. :: . * *:.: :...*.* * **..****: * *. :::*:.* : * ** . *.*:* * :.* . . * *:*::*** :* *:* *.*:* *:: * * ****::: .:.* : * :*** . ****.** *.: *: *.**:***:*****..* * *: *** ******:****** :. **.***::* : :****:... * *.** ::*** :::***::::*. :: ** :.*. ... * *:***:**. .: *::*::** *:: : ******* .: ..: .*:.: *.* : .* ::. * * * :.**:** : . * :.* .: : :* *:.**:: :.: ***:*..:.: *: ***::* * :*..: . : * .* *:: ***:* ** ::*.:: * .* * **.::.* *: *.* * :::*::::* *.:.* . ** . : *.* *..: *.: . **** : ::* *:*.: * : :**:..:..*. :.:.* . . :: * *.*:: : *:.:**:* .* * * :**** *.. * * :::**. :: . *:: *.*::..*... :*:. .:*:******:. * :* ** **.* *.**.:****:..** *.:.** * ****:: . :: : * * . :** *:*:.** * .** **: :. ** .: ::: ** *:* * :* :*::::*.*:* :** :*: ..** :: :::* .::********:*****.*:** *...:******: :*.**.:** **:::: ..*:** *. .: *. ..* ..***** * * * * *:*.*** ::***:*:***:*******: **:*:****** *:* **. ::* *:* * *:**:*: .**:*** .*.**:* * *:* *.* *:* * . . :.** * *.* ** ** **:* *:. . *: * :***:*:*: * :: :****:* : ** : :**:* :***: . :.*.***** . : *.: *:*:*: **:::* * *: :.** .. ..* ** .:***.* **:*.*.*:* * ****:*******:. . * *:* *..:* ***.:* ** : **.**** :****** ***::*..* :. *.***.*: ***::*. **:*** *.*.**** ***** .. .* * : : . **::**.*:*.** *** .******** * * **.* ***:** ****** : .* *: ****..*. ***: ** :***:: *:.*****.*:.**.***:**** *:* *:**** * .:**** * *.* * : ...:. :. *: . *. .:* **:::::.:*:*: :.:::.**.: ***.*.: :** : . .** ****::*. .:.:*::* . . *.:.*.::*********. ***:*: ** *** **** *:*****.*******. * *::** :.. . :*:*.*.:.*: * : . :*:****:* * .:*:**: * :**** :****. *:******** *:* :.********. ** *******:**: ***** ***:***********:**:::*:***:. * ***:::****:.* ..* ** ** *:.: * : *** ****.. :.*:***:*:**.** ***:** *** **: * : * *****.* :* *: * . .*:*: *:**.::***:** :: ***:*****: . *. ..*: *::*. *: *: .**:* :..: ::: : : ** .:*** *. : .***:*:***: :* :*: . ** .:.:. :: . * :*:******:::**:* . .* : .*** *:***.: ** :.* * . : : . .: *** :.: : * **. *. * * : :: ::* *:* .*. .*:: **:*. ***:*** ********.:*****.:**:*:*:*.***.* * * *:******:**** *:******: ** **: :*:*****:*.** .*.*:. ..* **:: :::.: :: * *: ::.*.*::: :** : .:* * . * . .:* . .*:. :. ** . . .*: *:.: *.* ** :**.*.*::*:*. .:::*: : *: *:*** :**:*:*:: *. ..* :..:: ****.: :* ::.::.*:*: ** *:.***: :: **:: ::*:: * ::* * * : *:.... ::*:: : :** *:: : **.* :** .. ::*:*****::**::****:*:*.***:** ::: **: .:: *::: :**:: . **. * : .:: : : * * : : * .. . .. :: :.: **: * : :** *: *.****** : *************::***:*:.************: ***** *. .. ** **:** .**** : * . .*. : . *. *: ..*::** *:**:.:****:*: * ::. * : . : ..: *. *: .. :: :: : . :..*.* . :*****.: ", "identical_positions": 1556, "similar_positions": 1407, "identity": "33.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100707-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P98161-1", "uniprot_id": "PKD1_HUMAN", "id": "P98161-1", "name": "Polycystin-1", "aln": "MPPAAPARLALALGLGLWLGALAGGPGRGCGPCEPPCLCGPAPGAACRVNCSGRGLRTLGPALRIPADATALDVSHNLLRALDVGLLANLSALAELDISNNKISTLEEGIFANLFNLSEINLSGNPFECDCGLAWLPRWAEEQQVRVVQPEAATCAGPGSLAGQPLLGIPLLDSGCGEEYVACLPDNSSGTVAAVSFSAAHEGLLQPEACSAFCFSTGQGLAALSEQGWCLCGAAQPSSASFACLSLCSGPPPPPAPTCRGPTLLQHVFPASPGATLVGPHGPLASGQLAAFHIAAPLPVTATRWDFGDGSAEVDAAGPAASHRYVLPGRYHVTAVLALGAGSALLGTDVQVEAAPAALELVCPSSVQSDESLDLSIQNRGGSGLEAAYSIVALGEEPARAVHPLCPSDTEIFPGNGHCYRLVVEKAAWLQAQEQCQ-AWAGAALAMVDSPAVQRFLVS--RVTRSLDVWIGFSTVQGVEVGPAPQGEAFSLESCQNWLPGEPHPATAEHCVRLGPTGWCNTDLCSAPHSYVCELQPGGPVQDAENLLVGAPSGDLQGPLTPLAQQDGLSAPHEP----VEVMVFPGLRLSREAFLTTAEFGTQELRRPAQLRLQVYRLLST-------AGTPENGSEPESRSPDNRTQLAPACMPGGRWCPGANICLPLDASCHPQACANG-----CTSGPGLPGAPYALWREFLFSVPAG-PPAQYSVTLHGQDVLMLPGDLVGLQHDAGPGALLHCSPAPGHPGPRAPYLSANASSWLPHLPAQLEGTWACPACALRLLAATEQLTVLLGLRPNPGLRLPGRYEVRAEVGNGVSRHNLSCSFDVVSPVAGLRVIYPAP-RDGRLYVPTNG-SALVLQVDSGANATATARWPGGSVSARFENVCPALVATFVPGCPWETNDTLFSVVALPWLSEGEHVVDVVVENSASRANLSLRVTAEEPICGLRATPSPEARVLQGVLVRYSPVVEAGSDMVFRWTINDKQSLTFQNVVFNVIYQSAAVFKLSLTASNHVSNVTVNYNVTVERMNRMQGLQVSTVPAVLSPNATLALTAGVLVDSAVEVAFLWTFGDGEQALHQFQPPYNESFPVPDPSVAQVLVEHNVMHTYAAPGEYLLTVLASNAFENLTQQVPVSVRASLPSVAVGVSDGVLVAGRPVTFYPHPLPSPGGVLYTWDFGDGSPVLTQSQPAANHTYASRGTYHVRLEVNNTVSGAAAQADVRVFEELRGLSVDMSLAVEQGAPVVVSAAVQTGDNITWTFDMGDG-TVLSGPEATVEHVYLRAQNCTVTVGAASPAGHLARSLHVLVFVLEVLRVEPAACIPTQPDARLTAYVTGNPAHYLFDWTFGDGSSNTTVRGCPTVTHNFTRSGTFPLALVLSSRVNRAHYFTSICVEPEVGNVTLQPERQFVQLGDEAWLVACAWP-PFPYRYTWDFGTEEAAPTRARGPEVTFIYRDPGSYLVTVTASNNISAANDSALVEVQEPVLVTSIKVNG-SLGLELQQPYLFSAVGRGRPASYLWDLGDGGWLEGPEVTHAYNSTGDFTVRVAGWNEVSRSEAWLNVTVKRRVRGLVVNASRTVVPLNGSVSFSTSLEAGSDVRYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSAQDSIFVYVLQLIEGLQVVGG----GRYFPTNHTVQLQAVVRDGTNVSYSWTAWRD-RGPALAGSGKGFSLTVLEAGTYHVQLRATNMLGSAWADCTMDFVEPVGWLMVAASPNPAAVNTSVTLSAELAGGSGVVYTWSLEEGLS-WETSEPFTTHSFPTPGLHLVTMTAGNPLGSANATVEVDVQVPVSGLSIRAS-EPGGSFVAAGSSVPFWGQLATGTNVSWCWAVPGGSS-----KRGPHVTMVFPDAGTFSIRLNASNAVSWVSATYNLTAEEPIVGLVLWASSKVVAPGQLVHFQILLAAGSAVTFRLQVGGANPEVLPGPRFSHSFPRVGDHVVSVRGKNHVSWAQAQVRIVVLEAVSGLQVPNCCEPGIATGTERNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIQVRAFNALGSENRTLVLEVQDAVQYVALQS--GPCFTNRSAQFEAATSPSPRRVAYHWDFGDGSPGQDTDEP-RAEHSYLRPGDYRVQVNASNLVSFFVAQATVTVQVLACREPEVDVVLPLQVLMRRSQRNYLEAHVDLRDCVTYQTEYRWEVYRTASCQRPGRPARVALPGVDVSRPRLVLPRLALPVGHYCFVFVVSFGDTPLTQSIQANVTVAPERLVPIIEGGSYRVWSDTRDLVLDGSESYDPNLEDGDQTPLSFHWACVASTQREAGGCALNFG---PRGSSTVTIPRERLAAGVEYTFSLTVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGRCLNCSSGSKRGRWAARTFSNKTLVLDETTTSTGSAGMRLVLRRGVLRDGEGYTFTLTVLGRSGEEEGCASIRLSPNRPPLGGSCRLFPLGAVHALTTKVHFECTGWHDAEDAGAPLVYALLLRRCRQG--HCEEFCVYKGSLSSYGAVLPPGFRPHFEVG----LAVVVQDQLGAAVVALNRSLAITLPEPNGSATGLTVWLHGLTASVLPGLLRQADPQHVIEYSLALVTVLNEYERALDVAAEPKHERQHRAQIRKNITETLVSLRVHTVDDIQQIAAALAQCMGPSRELVCRSCLKQTLHKLEAMMLILQAETTAGTVTPTAIGDSILNITGDLIHLASSDVRAPQPSELGAESPSRMVASQAYNLTSALMRILMRSRVLNEEPLTLAGEEIVAQGKRSDPRSLLCYGGAPGPGCHFSIPEAFSGALAN-LSDVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQAGAQIPIERLASERAITVKVPNNSDWAARGHRSSANSANSVVVQPQASVGAVVTLDSSNPAAGLHLQLNYTLLDGHYLSEEPEPYLAVYLHSEPRPNEHNCSASRRIRPESLQGADHRPYTFFISPGSRDPAGSYHLNLSSHFRWSALQVSVGLYTSLCQYFSEEDMVWRTEGLLPLEETSPRQAVCLTRHLTAFGASLFVPPSHVRFVFPEPTADVNYIVMLTCAVCLVTYMVMAAILHKLDQLDASRGRAIPFCGQRGRFKYEILVKTGWGRGSGTTAHVGIMLYGVDSRSGHRHLDGDRAFHRNSLDIFRIATPHSLGSVWKIRVWHDNKGLSPAWFLQHVIVRDLQTARSAFFLVNDWLSVETEANGGLVEKEVLAASDAALLRFRRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRIQRATCCVLLICLFLGANAVWYGAVGDSAYSTGHVSRLSPLSVDTVAVGLVSSVVVYPVYLAILFLFRMSRSKVAGSP--SPTPAGQQVLDIDSCLDSSVLDSSFLTFSGLHAEQAFVGQMKSDLFLDD--------------SKSLVCWPSGEGTLSWPDLLSDPSIVG-----------SNLRQLARGQAGHGLGPEEDGFSLASPYSPAKSFSASDEDLIQQVLAEGVSSPAPTQDTHMETDLLSSLSS---TPGEKTETLALQRLGELGPPSPGLNWEQPQAARLSRTGLVEGLRKRLLPAWCASLAHGLSLLLVAVAVAVSGWVGASFPPGVSVAWLLSSSASFLASFLGWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSARVP-RVRPPHGFALFLAKEEARKVKRLHGMLRSLLVYMLFLLVTLLASYGDASCHGHAYRLQSAIKQELHSR-----AFLAITRSEELWPWMAHVLLPYVHGNQSSPELGPPRLRQVRLQEALYPDPPGPRVHTCSAAGGFSTSDYDVGWESP-HNGSGTWAYSAPDLLGAWSWGSCAVYDSGGYVQELGLSLEESRDRLRFLQLHNWLDNRSRAVFLELTRYSPAVGLHAAVTLRLEFPAAGRALAALSVRPFALRRLSAGLSLPLLTSVCLLLFAVHFAVAEARTWHREGRWRVLRLGAWARWLLVALTAATALVRLAQLGAADRQWTRFVRGRPRRFTSFDQVAQLSSAARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELLGVTLGLVVLGVAYAQLAILLVSSCVD---SLWSVAQALLVLCPGTGLSTLCPAESWHLSPLLCVGLWALRLWGALRLGAVILRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWMGLSKVKEFRHKVRFEGMEPLPSRSSRGSKVSPDVPPPSAGSDASHPSTSSSQLDGLSVSLGRLGTRCEPEPSRLQAVFEALLTQFDRLNQATEDVYQLEQQLHSLQGRRSSR---------------------------------------------APAGSSRGPSPGLRPALPSRLARASRGVDLATGPSRTPLRAKNKVHPSST--------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O08852-1", "uniprot_id": "PKD1_MOUSE", "id": "O08852-1", "name": "Polycystin-1", "aln": "MPLGAPALLALALGLGLWLGALAGDPGRGCGPCPLPCFCGPAPDAACRVNCSGRWLQTLGPSLRIPADATALDLSHNLLQTLDIGLLVNLSALVELDLSNNRISTLEEGVFANLFNLSEINLSGNPFECNCGLAWLPRWAKEHQVHVVQSEATTCRGPIPLAGQPLLSIPLLDNACGEEYVACLPDNSSGAVAAVPFYFAHEGPLETEACSAFCFSAGEGLAALSEQNQCLCGAGQASNSSAACSSWCSSISLSLNSACGGPTLLQHTFPASPGATLVGPHGPLASGQPADFHITSSLPISSTRWNFGDGSPEVDMASPAATHFYVLPGSYHMTVVLALGAGSALLETEVQVEATPTVLELVCPSFVHSNESLELGIRHRGGSALEVTYSILALDKEPAQVVHPLCPLDTEIFPGNGHCYRLVAEKAPWLQAQEQCR-TWAGAALAMVDSPAIQHFLVS--KVTRSLDVWIGFSSVEGTEG-LDPRGEAFSLESCQNWLPGEPHPATAEHCVRLGPAGQCNTDLCSAPHSYVCELRPGGPVWDTENFVMGMSGGGLSGPLHPLAQQETVQGPLRP----VEVMVFPGLSPSREAFLTAAEFSTQKLEEPAQMRLQVYRPSGG-------AAAVPEGSS----EPDNRTEPAPKCVPEELWCPGANVCIPFDASCNSHVCING-----SVSRLGLSRASYTLWKEFFFSVPAG-PPTQYLVTLHSQDVPMLPGDLIGLQHDAGPGTLLQCPLASSCPG-QALYLSTNASDWMTNLPVHLEEAWAGPVCSLQLLLVTERLTPLLGLGPNPGLQHPGHYEVRATVGNSVSRQNLSCSFSVVSPIAGLRVIHPIP-LDGHIYVPTNG-SVLVLQVDSGANATATAQWFGGNISAPFEDACPPEVDFLKQDCTEEANGTLFSVLMLPRLKEGDHTVEIVAQNGASQANLSLRVTAEEPICGLRAVPSPEARVLQGILVRYSPMVEAGSDVAFRWTIDDKQSLTFHNTVFNVIYQSAAIFKLSLTASNHVSNITVNYNVTVERMNKMHGLWVSAVPTVLPPNATLALTGGVLVDSAVEVAFLWNFGDGEQVLRQFKPPYDESFQVPDPTVAQVLVEHNTTHIYTTPGEYNLTVLVSNTYENLTQQVTVSVRTVLPNVAIGMSSNVLVAGQPITFSPYPLPSTDGVLYTWDFGDGSPVLIQSQPVLNHTYSMTGAYRITLEVNNTVSSVTAHADIRVFQELHGLTVYLSPSVEQGAPMVVSASVESGDNITWTFDMGDG-TVFTGPEATVQHVYLRAQNFTVTVEAANPAGHLSQSLHVQVFVLEVLHIEPSTCIPTQPSAQLMAHVTGDPVHYLFDWTFGDGSSNVTVHGHPSVTHNFTRSGIFPLALVLSSHVNKAHYFTSICVEPEIRNITLQPERQFVKLGDEARLVAYSWP-PFPYRYTWDFGTEDTTHTQTGGSEVKFIYREPGSYLVIVTVSNNISSTNDSAFVEVQEPVLVTGIRING-SHVLELQQPYLLSAMGSGSPATYLWELGDGSQSEGPEVTHIYSSTGDFTVRVSGWNEVSRSEAQLNITVKQRVRGLTINASRTVVPLNGSVSFSTLLEVGSDVHYSWVLCDRCTPIPGGPTISYTFRSVGTFNIIVTAENEVGSAQDSIFIYVLQFIEGLQVAGGDN--GCCFPTNYTLQLQAAVRDGTNISYSWTAQQEGSLITLFGSGKCFSLTSLKASTYYVHLRATNMLGSAAANRTIDFVEPVESLILSASPNPAAVNMSLTLCAELAGGSGVVYTWYLEEGLS-WKTSMPSTTHTFAAPGLHLVRVTAENQLGSVNATVEVAIQVPVGGLSIRTS-EPDSIFVAAGSTLPFWGQLAEGTNVTWCWTLPGGS------KDSQYIAVRFSTAGSFSLQLNASNAVSWVSAMYNLTVEEPIVNLMLWASSKVVAPGQPVHFEILLAAGSALTFRLQVGGSVPEVLPSPHFSHSFFRVGDHLVNVQAENHVSHAQAQVRILVLEAVVGLQVPNCCEPGMATGTEKNFTARVQRGSRVAYAWYFSLQKVQGDSLVILSGRDVTYTPVAAGLLEIHVRAFNELGGVNLTLMVEVQDIIQYVTLQS--GRCFTNRSARFEAATSPSPRRVTYHWDFGDGTPVQKTEEF-WADHYYLRPGDYHVEVNATNLVSFFVAQATVTVQVLACREPEVEVALPLQVLMRRSQRNYLEAHVDLRNCVSYQTEYRWEIYRTASCQRPGRMAQMVLPGVDVSRPQLVVPRLALPVGHYCFVFVVSFGDTPLARSIQANVTVAAERLVPIIEGGSYRVWSDTQDLVLDGSKSYDPNLEDGDQTPLNFHWACVASTQSETGGCVLNFG---PRGSSVVTIPLERLEAGVEYTFNLIVWKAGRKEEATNQTVLIRSGRVPIVSLECVSCKAQAVYEVSRSSYVYLEGHCHNCSRGYKQGCWAARTFSNKTLVLNETTTSTGSTGMNLVVRPGALRDGEGYIFTLTVLGHSGEEEGCASIRLSPNRPPLGGSCRLFPLDSVRGLTTKVHFECTGWRDAEDGGAPLVYALLLKRCRQS--YCENFCIYKGSLSTYGAVLPPGFQPLFVVS----LAVVVQDQLGAAVVALNRSLTIVLPEPSGNPADLVPWLHSLTASVLPGLLKQADPQHVIEYSLALITVLNEYEQAPDVS-EPNVEQQLRAQMRKNITETLISLRVNTVDDIQQITAALAQCMVSSRELMCRSCLKKMLQKLEGMMRILQAETTEGTLTPTTIADSILNITGDLIHLASLDMQGPQPLELGVEPPSLMVASKAYNLSSALMRILMRSRVLNEEPLTLAGEEIVALGKRSDPLSLLCYGKALGPSCHFSIPEAFSGALSN-LSDVVQLIFLVDSNPFPFGYISNYTVSTKVASMAFQTQTGTQIPIEQLAAERAITVKVPNNSDQAAQ---SSHNPVGSTIVQPQTSVSAVVTADNSNPQAGLHLRITYTVLNERYLSAEPEPYLAVYLHSVSQPNEYNCSASRRISLEVLEGADHRLYTFFIAPGTGTLDRSYYLNLTSHFHWSALEVSVGLYTSLCQYFSEEMMMWRTEGIVPLEETSPSQAVCLTRHLTAFGASLFVPPSHVQFIFPEPSASINYIVLLTCVICLVTYVVMAMILRKLDQLDVSRVRVIPFCGKGGRFKYEILVKTGWSRGSGTTAHVGIMLYGEDNRSGHRHLDGDRAFHRNSLDIFQIATPHSLGSVWKIRVWHDNKGLSPAWFLQHIIVRDLQSARSTFFLVNDWLSVETEANGGLVEKEVLAANEAALWQFQRLLVAELQRGFFDKHIWLSIWDRPPRSRFTRVQRVTCCVLLLCLFLAANAVWYGVVRDTTYSMGPVSSLISPGVDTVAIGLVSSVVVYPVYLAVLFLFRMSRSKVSGDQ--NPTPTGQQALDVDSYLDPSVLDSSLLTLSGLT--EAFAGQVKNDLFLED--------------AKSLVCWPSSEGTLSWPDLLSDPSVVS-----------STLQRLTQGRPGCMLGSEEDGASLVSPSLPAKYLSASDEDLIHQVLADGANNLVPTQDTLLETDLLTSLSS---VPGEKTETLILQTVGEERPASMGLSWEQSPVTRLSRTGLVEGFQKRLLPAWCAPLAHGLSLLLVAVAVAVSGWIGASFPPSVSVMWLLSSSSSFLASFLGWEPLKVLLEALYFSLVAKRLHPDEDDTLVESPAVTPVSERVP-RVRPPHGFALFLAKEEARKVKRLHDMLKRLLVYMLFLLVTLLANYGDASCHGHAYRLQSAIKQELDSQ-----AFLAITRSDEFWPWMSHVFLPYVHGNQSSPELGPPRLRQVRLQEAFCPDPSSS-EHMCSAAGSLSTSDYGIGWQSVVQNGSETWAYSAPDLLGAWYWGYCAVYDSGGYIQELGLSLEESRARLGFLQLHNWLDSRSRAVFVELTRYSPAVGLHAAVTLRLEFPVAGHALAAFSVRPFALRRLSTGLSLPLLTSVCLLLFALYFSMAEVQTWRKDGCACTARPDTWARCLLVILTAATGLVRLAQLGIADRQWTHFVQDHPRHFTSFDQVAQLGSVARGLAASLLFLLLVKAAQQLRFVRQWSVFGKTLCRALPELMGATLGLVLLGVAYAQMAILLISSGAD---TLYNMARAFLVLCPGARVPTLCPSESWYLSPLLCVGLWALRVWGALRLGAILLRWRYHALRGELYRPAWEPQDYEMVELFLRRLRLWMGFSKVKEFRHKVRFEGMDPLPSRSSRGSKSSPVVLPPSSGSEASHPSTSSSQPDGPSASLSRSTLKLEPEPSRLHAVFESLLVQFDRLNQATEDVYQLEQQLQSLQGHGHNG---------------------------------------------PPSSPSPGCFPGSQPALPSRLSRASQGLDQTVGPNRVSLWPNNKVHPSST--------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9QMX0-1", "uniprot_id": "A0A8M9QMX0_DANRE", "id": "A0A8M9QMX0-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANILHLPLIWILCVFTSCFSEK-------------------------------------------------------DCPKGAKIDRDGLRCYWMPSFTSTWLEARGICQRDERGGDLALVDSVTVQSFIQNSFRLEDPVGVWMREGMAEGLFGDLDAED------------------REKKCFSMALASGQWMNEQCNKRNFVICEKTISVSLPSLESYVTGVP---LMSGVYTVSQIQLLPSPPDPGPHLVEIMLFPGLWFSHEGRVLSLEMVTQPSDQMTFARMQILRPYCSPSHHLVPPGCSSLLNPFSCCSLMAMCNTTGGCSSGQYWCHLLEICLPVTSPCSPYNSFNAGHDFALPPRYPVTPPFFHLMADMSLMLPPSSEHTHIRATVQDKHITVYPDDILALQHNRRAGEFLHCVAS-TSSAWRQSYLSLPGPEWG----GWFEGSFSVQPGKGQWLDGVICDLQVIYEDPMP---------------HYVISPTPNSPMNAESPVTGLQVLHPKLDKNNQMYVPVNVTTLIVIRIISGEHVTSSWSAPVSKSGVPFVSSCP-------VEMPETEEGGWFSHVYMELSGQEEYILNIKASNSLSAQTLSVRVVSHIPVSGLSIMPEGFRRVLVDIQQVFTASVTTGSSVTYSWVIDDLVQFAHTGESYSVVFKNPAEYTLKVMAHNPVSSQLMKVKLIADVMTPLDDLIVISMPEAIAVNTSTRYTIQVKADISIGVTIRWDFGDNTASVSHTVSPSSE-IEELQQRAKHVYLQDSIQHTFASPGDYTLKIKAYNKYDQIEKAETVKVRTPISNLLVSSSPAVCQVNYTVLFEVSLWPSSFGALYSWNFSDDCEKVKEVYNKVSHVFNKPGTYNVTIMANNTLSTLTNYTAVEVIEPVSGLQLNYNISIELNSAFKISGKVSSGTHLKWTFEFGDGTTVINHTGSSASHMYESPGNYTVQVSAYNSVSQEHQLVSIEVYCLIITQITPTDCVLSQTEIDFEVLVKGFIPALTFEWEFGDGTPLSVVKGATSVTHTFKTAGTYTVGVNAHSLVTSVYYESSICVEGQITDVSLSSPNSAVAVSEVICFDASVLPKVTEYQFWWHNNFSSDTNPVKGLSHHCFMFQEEGLCEISVLVYNKVSNGTAKTIILVQRAVSNLCIKYEGNHDAMTVNQSYHFWAELLGKMASFQWDFGDGSKTEGQNQLHIFGFPGQFHVTVTASNAVSSDSVTVEIEVQAPLSYVMVNTSRPFVEAGKEILITALTDVRENISFFWTVNPSTPPKIGTSTFTHVFPNAGVFEIQVAAQNLVSRVEAITHIEVVEKIYGVWIQGQGLRSEKYFLTNQTILLEASVTHGSNLTYKWTANNS-----MAGNTKQFPLFTKNSGDIHVRLVVSNALGLVDSELSLRSVELVSGLSIVSPVKTVTKGKPVNISAILASGTDIKYSWFLDCEHCPVISDVPFILHAFKICGVVKIRVSASNVFGSEEATKLLTIEENISKVDFQINGQSRPFFVKSNHLLMLFGSAGPGNVLHWEWVLTLHNRTVVVLTDNQTVSYSFVDAADHRLSLNASNDISWQTVSYTITVQDAIQGLSLTSSSSVVCEDDSVTFLTSVSKGSEVSVSLEFVNASYSVDIGRDFTTYSLAVGNHLVRATAKNKVSSQTATATVRVVERIRDLRLIGCCSAVLEASKNISFQASAFS--QANYHWTFLLNGVQSS---REIGQHVHFTPFANGSLSVTVEAENGFCSQSLTSTATIQKHLKKVTLLTSHDGAFIDYPVTFVAITDGGSD-LKFIWDFGDASEGLLVTDYNKQVHKYNVAGEFLVKVTAFNNISEVSVQIAIEVQNLVCTQPHIYTVKEEYNVLK-SRPSFFEARVDFNGCVTHKASYIWEIFRGPDCP--GMNKVNLNHSVDVTTPLLSLPKHTLKVGNYCLTFTARLKGTPLQQNKTIKLNVVHSRLIPVIKGGSLRLWSCLCDLTLDATESFDPDSEKNDIDLFKFQWSYTIENTTALSLAISTLHGHISGNSSMLILPRSVLLPDRVYRFTLTLFKSGRQPASISQSVRVYNATLLTVTVKCVSCNNQLFHMN-HNDHVSLAGYCSSCQDTIQYR-WTAENQRGEALTLNEVTTLTGSLRREIVIKPGVLMEGQEYTFTLNVSDPASGLWGSASITLVSNHPPYGGFCTLSPDDSLYFLETKVSYSCSGWMDDDGDSAQLIFSLQVAQCEDFGPLCPLITLYRGTQSTLSSLVPLGIKNTVENASVIHVLVHIEDSMGATVVAVKKKLTVLP-----CDQCTVTWLKKRSQSEFWALIQQGNPQDIMQYSFALTSQLNQLTS------ISAQELEDKIHIRTRVIQVLASLPVSSLQDVALISSALAQSTVVPSEVQCSGCYAKVLQVTKKMIKVIREQTGEGNINPTDTGRNILTVLSNTMTADLRQRSTP-------DTSEHIRAVSALGQVFELMRSLMLSRMRGGTALFLAIPKISAVGIQGDPTEDLRCKDVLT-HCQFHIPPALSSQLKEEKQEVLQILLQMENEENPFIPGAEPPISTMLAAMEFATPQGNPISIANLTLDSAIQVTLHKQAQEMKD----ESLLWKNITLKHNGSVNFTVKAMDAEPHTGLYVALNFSLIPG--SAEKASGLVWISINDQPVDLQSGRIHHQELTIFLSAQTPLLQHIIFLTPLLNGSAKELFVKVNSSIGGVDVTVSVCVFSVLCRFFDVKELRWSSDGLSPLSTSSPHSAHCLTQHLTMFGASLFIHPEALLLLPPSEEPVRNVVVGIICGVLLLIHLLVGLMAHKLDHLENLRLCWVPLCGQKGRYQYRVLVKTGWKRGSGTTAHVGISLYGLN-KSGSRHLQRQGAFQRNSMDDFQVETDANLGEIWKIRIWHDNTGLDPSWYLQHVIVWDIQTENMFFFLVEDWLSVENEKNSGRVEKVILASCPQELHQFKRILHSQLLFGLQEHHLWISLWERPTHSRFSRAQRVTCCALLLHLYLAAGAVWYGAVGRKG-SSGRVSTQMVMNAETVLVGMTVAALTFPFQAILKFLFQRTKSKVTLEVSAPPSPVSHTVEMDVFLSHPDLTCSSFLSLPTCPKSSIYDGPSPFTNSLQSKKLDSEFWNSPDPRNGRVDQLPSCDSIFGLPELTGTTHLLKRKKALLQLHLSTPTSDHDNGELAKSSASEEDLRTISPDMDLTNTLSSDPEASDSGNFTPNDTIPTDTQDSFCSEWSDLSVDTPTYEPGFHRSSSSLSVLSEASTFLPSLPPDSISTVSTTRIGVVRGVPGFYLPSWVLRMVHLLVAVLLGTCLAVVGLYGSSFTSSVVLMWLVSTLSAVLTSALLLEPLAICIQALYLATVVRPVDPEVEERLAQETEVRRSEEDFRDKVHPLCGYGLLQAKEEARKLRTLRALMRSCLVYMLFLLVVLMVNYQEHVQMADSRRLHSAIKHTLISASAGKPGLMKLSGWMNAEQWINEKLTSHLYENPSLLLTGPARLQKVYFQDFCS---QGIRDQFQSGRLSLMPTAHVSSHANPGQQTSTAHSKNTPALSTWQKRALCAFSQTEELVLGN--NTEYTRQILSDLQKEKWMTTGTKAVLIEFTQYHKQTSILAPVSILLDQTQTGRILAFISIQPFHISPLSG-PDLHVTLTVVLLLFALCFLSTEVRALIRKPSQYLRQAWCWFQTLLALLALAAAVLRLYFLYTTTVCISRYR-SIPSSFADFHSAATVARKSNQLSAILLTLLALKMVGILQFVRRWLVMGRVIWQVFPQICGVVFLLLLLLLLFSHIGMMLFSGSVEGFRTLGQASSSLLCLLRGRTGLQRLCEHHPVVGPLYCLSAVGIGFWVLGRLCAAVLIRTYQMVQADIYRPSMEPQDYEMVQFLIKRLKLWMGLSKTKEFRHRVKFEGMRPPPSRSSQVSASSNCWTPLSPIGSRQTLLSSASSLASDTSVISDS-CDVHPYVERLVPCVDSLLAGFERVNQVTEEVYNFELQLQQIQSRISQIRKLPLPVTFTECDLTPKPPLLPRHPSSSVLESKPSPSCLLNTLPYRRAAHSESSLMGPAVQLGRRILSALDGGRMNSPNPRKRVVPRQRAWNSVTCHSADTAQWIAGFHNTDGPLVRPQSQDEDRQRGCEGMPIKRRAWQTEKEL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. *:. : * . :: : . ** .::* .. :** : .:.**:*: *: *. **:*** ::* *: . :: .:.**: . .:* ... : .:* .: *. : :** . .: . *. : * . * . : .::* : : .* * **:*:**** *:*. : : *: ** . : *:*: * .. . . : : * . ** ::*:*. :.* . . *. . :. . : * :: : :*.. :: .*::.:.: : *.*::.***: .* :*:* : .. : *** ...* :* ::: : * . :: * * : * . ...:.. **::**:*::* :.::***.* : :*::: ** :.*:: .. .. * . ** . :. ** : : : :: ::: ..*. * .**:**.:. *:.** *. *** .: ::. * :**.:.: *.*:* .::. . :.*:::..* :.*.: * * **. :: :: .: *. :..* * ::* .:. *:: * * .* :: *:: * ***. : : .* .* : : . :* ::.. * :::**:* *.: . * :::: : .*.**: :..: :. * * .. .: * **. *.**:*:*.*.. : : .*.: *:*.: : .***:* : : :.*:: : ** : . ::* .:.. :*. *.:* ::.***::*** **:. . ::..*:* . * ** * * ....: : : : *: * : :: *: *: :*.. : . *.* *:* ****:. .*:* .:***.*. :* :.:.: * *. .:* :***** :: :::*.. .. * :.: : * * *:: *. . .. : . .. *:::: * : * . *::* . .::: **..* *: :* : ::*.* : * * *:: *::***. ** : * :. .*:* * *:. * ** ... ::: *: : : :*:**..* . .: ::: :. .:: : *.: .* * .*:::.* ..*.*:* *:*:* *. .: .: *:: * *: : * * ** *: *:* * .*:*::*.*** .. : *. * *.* ::. :*:* .:* ** . :: :: ** * * : :. :..: . .:.:.* **.*:.: *:* *: . :. * *:* *: : ::* * :** :** : :: :. :.:: . :. ** :. : ::*. . *. : * *.:. . . . :: * *. . : ***** :** :. *.:*.::.* .* * :**.**. .: * * :: ** ::. *:. .: .* . *: **:*:* . .:*:** * . : *:* : .*:: .**.. : :..: .* * . :. * * * *: **.. *:.* :**.* * *.: *.* * : . . * :*. :: *:* : . .* : .. * * *. .. : : *****.: . : * * .*:: *:*.* * :* . .* :: ** *.* :*.: .. ::: *: .::**:**:..**::::.* **::* ..* * .***: * * :*: :* **:**:.*.. : .*** :. ::.*. .**:*:*:*** *:** **.**.::*:**: *..* :.*:*: . .. . . .: . .** : :* . * .. * *.* ::*:**: : .*:* : .. : *:::****: * .: :..:* * * * .*. : *:*.. .::*.*:*.** *** .:*:: *.* :*: * ***.* . :. *.*** * .*:** ** * * * .:: * *** :.*:** * :. .* *:::* : :*.: * : :*:*: *: .:::* *:: . . : * ::*.:**:***:::.*:: . **: : * : .*::*.:**.:::**:** : **: . * : : ::*..: :.* ** * :::*: *::****. . *: * .* : *: : *: ::: :* *.:.** . .**.: .: : : * :... : * .* . *** ** **: . .* ** :* * * :.** . * . *:* ** *:*. * : .:*:*::: ::.: ** :: .:** :*:* * * * *.* .*: : ** *.: :::: . . :: : **. .*. .::* :**:: :.:::: : :.. : : ::. . : . :.: : : :*::* . .:::.* : : *** ::: **::*. : : * ::*: **. :** .* ***:*** ******: *. : :: *. . * :* : * : *: ::::. : :***:*: * :*:**: **::*.:****** *********** *** : :** ***: : **:***:* *:: * .**.:****:****.**.*:*:***:** *:*: . ****:******.* *.* *** :**: * :*:*:* ::* *: ::*:*:*:*:**.:***:* **.***.**: *:*.*.*****.* . * * ** ..:** :*:. :.:.:*. : ***: ::***: . *:*..: . ...: **:*::. . : * *:. : ** :. :. *:* . . :: : .*. . ..*** :: . :: :*:. * :: . . . ***: . *:.: ** : .: *. :.* . .* :. .. :* *:*.*. **:* :.* * :*:...:** * *:**...* : **:*: ::.*:* * *** : ::***:: *.: :.*: :: *.:.. * . . :*:* *:.*: *******:: *: ::: *********.*:..* : ..: **:****: * * .:: :: : *: . : .::: * * **.**::* :*: . : *. .: .: : . . :: * : : .:* * . **. :: : . * :* * ** .:*: . ::**::*:*:* ..: *.*:: *: . :*: ** :*::** : ** .* : :* *****: * :*.:: :. : * : **. *: *:.::** * : ::: . * *:.*...* :. :. *:* ** ** :* . *:***:* *:*:.: :.:*:: *..: *::* : ::::.::*.*. .: :* . : ::* * * . :.** *:. .: .* ** * :* *: ::.::***: ********:::::**:****:**.*****:*:**** * *****: * * * *. .. . :*:*. . : :. .* .** . .::**. *:*:**.**:**::* **:.:*.: . :. * . * * *: * * * : ..::. * * ", "identical_positions": 1027, "similar_positions": 1400, "identity": "22.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100712-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TN22-1", "uniprot_id": "TXD16_MOUSE", "id": "Q7TN22-1", "name": "Thioredoxin domain-containing protein 16", "aln": "MMSSGFSVFRAGVALVLMCSFYKSTEDSLPELTPQQYFSTLQPGKASLVYFCQVGSLSNSVFLEELKEAVKPLQDYGISVAKVTCVEEEASRYCGEEEGLMKAYLFRGNILLREFPTDILFDVNAIIAHVLFALLFNEVKYITTLEDLHSIENSLKGKSNMIFSYVEAIGTPEHRAVMEAAFVYGTSYQFALTTEIALLENIGSE--SIEHAHLYFFHCKLVLDLTEHCRRTLMEQPLTTLNIHVFVKTMNAPLLMEVAEDPQQVSTVHLQLGLPLVFIISQRATQEADRRTAEWVAWHLLGKAGVLLLLRDSMDVNIPQHANVAFRRAEKDVPVEFLVLNDVELIISHVKNNMHIEEIQEDEGEDME-GPDLAVEDDEVAGTVYRDRKKPLPLELSVELTEETFNTTVMTSDS-IVLFYATWHAVSMAFLQSYIDVAIKLKGRSTILLTRINCADWSDICTKQNVTAFPVVKLYK-EGESPVSYAGMLATKDLLKFIQLNKISCPVNIASIQEAEKYLRGELYKDLPSSASVSVLGLFSPAMASAKELFREAGKQLRGSVITGIYSEDDVWILSNKYATTLPALLLARPKEGRIESVPLDTTLVQDMAQILANALLEAFPEITVENLPTYLRFQRPLLLLFSG---GSINPQYRNTILALVRQKQLDSFTPCWLNLKNTPVGRGILKAYFGRLPPLPQLLLVNLHSGGQVYAFPSSQSVTEQSLVLWLKHLQAGLENPITVLSAQEWKPPLPAFDFLNMMDAPTSQAPTKKVLECQKEAEVQESAELQPGDRSTARREPVEMLRIKRWNTANWPKDTQEPFHHDKEL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2K2-1", "uniprot_id": "TXD16_HUMAN", "id": "Q9P2K2-1", "name": "Thioredoxin domain-containing protein 16", "aln": "-MFSGFNVFRVGISFVIMCIFYMPTVNSLPELSPQKYFSTLQPGKASLAYFCQADSPRTSVFLEELNEAVRPLQDYGISVAKVNCVKEEISRYCGKEKDLMKAYLFKGNILLREFPTDTLFDVNAIVAHVLFALLFSEVKYITNLEDLQNIENALKGKANIIFSYVRAIGIPEHRAVMEAAFVYGTTYQFVLTTEIALLESIGSE--DVEYAHLYFFHCKLVLDLTQQCRRTLMEQPLTTLNIHLFIKTMKAPLLTEVAEDPQQVSTVHLQLGLPLVFIVSQQATYEADRRTAEWVAWRLLGKAGVLLLLRDSLEVNIPQDANVVFKRAEEGVPVEFLVLHDVDLIISHVENNMHIEEIQEDEDNDME-GPDIDVQDDEVAETVFRDRKRKLPLELTVELTEETFNATVMASDS-IVLFYAGWQAVSMAFLQSYIDVAVKLKGTSTMLLTRINCADWSDVCTKQNVTEFPIIKMYK-KGENPVSYAGMLGTEDLLKFIQLNRISYPVNITSIQEAEEYLSGELYKDLILYSSVSVLGLFSPTMKTAKEDFSEAGNYLKGYVITGIYSEEDVLLLSTKYAASLPALLLARHTEGKIESIPLASTHAQDIVQIITDALLEMFPEITVENLPSYFRLQKPLLILFSD---GTVNPQYKKAILTLVKQKYLDSFTPCWLNLKNTPVGRGILRAYFDPLPPLPLLVLVNLHSGGQVFAFPSDQAIIEENLVLWLKKLEAGLENHITILPAQEWKPPLPAYDFLSMIDAATSQRGTRKVPKCMKETDVQENDKEQHEDKSAVRKEPIETLRIKHWNRSNWFKEAEKSFRRDKELGCSKVN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FC06-1", "uniprot_id": "E7FC06_DANRE", "id": "E7FC06-1", "name": "", "aln": "-MCT---VYLVTFVFILTAEQCFS---KLMEDSGQNLMERMQTGKTSFIYFGNHVNPTIELFIEQLQMSADALEDYGIAVVMVNCSKDDIAKYCTGEKLLTKAYLFRGSEVLRSFDIDTVFDVNAIVSHVLFSVLFNEVLYVHTPAELLGVESAAKQNSDIVVGHIPVLGLPEHRALMETAFVYGTKYQFVQTTGSLVLKRMGVVNPSSSQARLWFLHCKSVSLQSDPCPSTAMSKPINTINIHTFLQLMEAPLVTEAVTDPSEVDVVHIHLSVPVLYLFSQPQTQHLDRDTAQTVALQLRGEVGVVLIHRDNPKVKTPLKYNAAYRLPQE--DVKYFTLSAPEEVVKLFKETLLQKDKTEDEEEDDEHWSDLDILDDEVSESVYRDRDLMLDLEPVTELTADTFQTAIKQNEITVVLFYFKWDAVCMAFIQSYVEVAEAVEDVNGVELAAVDCGEWTDICRDQNITSFPTVLIYCPKAAAAQPYRGMMGTKSLQRFILLSLVSTPVHLSSSAEVMSFLEGDLYRKYVYLTPVRVLGLFSSMQDMGVSSFEEAARLLRGETIIGLFAHKEAAKWVEGLSVNLPALLVSHGPALPHQVFSLPSSLATDHVKLIQRVELERFPELTVENLPWYLELEKPLLLLFIGKEESTESTRSLAEINQLLGSGQLDFFLPCWIHLGRTPVGRSILEKYLGFVPPLPSLVISQIKTGGEVFLFPSERPLKAENILRWIHDVEDRHEQPAGLIPDVKWGPPVPFFDFLAIMDQEAPTYAAQKAPKTKNGG--RENHKEQ--NHVTPNQ-----------SQGPHPSANPQAPRRHSEL------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 270, "similar_positions": 305, "identity": "32.37%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100712-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63644-1", "uniprot_id": "ROCK1_RAT", "id": "Q63644-1", "name": "Rho-associated protein kinase 1", "aln": "-----------MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLP--SANPSENRS-SSNVDKNVQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDK----IMKELDEEGNQRRNLESAVSQIEKEKMLLQHRINEYQRKVEQENEKRRNVENEVSTLKDQLEDLRKASQSSQLANEKLTQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSVSQLESLNRELQERNRMLENSKSQADKDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSIQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVETEKQCSMLDVDLKQSQQKLEHLTENKERLEDAVKSLTLQLEQESNKRILLQSELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNR---ENLRKIQELQSEKETLSTQLDLAETKAESEQLARGILEEQYFELTQE-------SKKAASRNRQEITDKDHTVSRLEEANNALTKDIELLRKENEELNERMRTAEEEYKLKKEEEISNLKAAFEKNISTERTLKTQAVNKLAEIMNRKDFKIDRKKA---NTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHRNELQMQLASKESDIEQLRAKLLDLS---DSTSVASFPSADETDGNLPVGSACIPYLFIFYSSSSRIEGWLSVPNRGNIKR-YGWKKQYVVVSSKKMLFYNDEQDKE-QSSPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILYANEGECRK-----DIEVEPVQ---QGEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALECRRCHVKSHRDHLDKKEDLIPPCKVSYDVTSARDMLLLACPQDEQKKWVTHLVKKIPKKAPSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTS----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70335-1", "uniprot_id": "ROCK1_MOUSE", "id": "P70335-1", "name": "Rho-associated protein kinase 1", "aln": "-----------MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLP--SANASENRS-SSNVDKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNLKLDK----IMKELDEEGNQRRNLESAVSQIEKEKMLLQHRINEYQRKVEQENEKRRNIENEVSTLKDQLEDLRKASQTSQLANEKLTQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQADKDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSIQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVETEKQCSMLDVDLKQSQQKLEHLTENKERMEDEVKNLALQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNR---ENLRKIQELQSEKETLSTQLDLAETKAESEQLARGILEEQYFELTQE-------SKKAASRNRQEITDKDHTVSRLEETNSVLTKDIEMLRKENEELNERMRTAEEEYKLKKEEEINNLKAAFEKNISTERTLKTQAVNKLAEIMNRKDFKIDRKKA---NTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHRNELQMQLASKESDIEQLRAKLLDLS---DSTSVASFPSADETDGNLPE---------------SRIEGWLSVPNRGNIKR-YGWKKQYVVVSSKKILFYNDEQDKE-QSSPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILYANEGECRK-----DIEVEPVQ---QGEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALECRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNPPSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTS----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13464-1", "uniprot_id": "ROCK1_HUMAN", "id": "Q13464-1", "name": "Rho-associated protein kinase 1", "aln": "-----------MSTGDSFETRFEKMDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYKDTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFPDDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLSSDIDTSNFDDLEEDKGEEETFPIPKAFVGNQLPFVGFTYYSNRRYLS--SANPNDNRT-SSNADKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDK----IMKELDEEGNQRRNLESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKEEIEEKNR---ENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQYFELTQE-------SKKAASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMKKAEEEYKLEKEEEISNLKAAFEKNINTERTLKTQAVNKLAEIMNRKDFKIDRKKA---NTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECAHRNELQMQLASKESDIEQLRAKLLDLS---DSTSVASFPSADETDGNLPE---------------SRIEGWLSVPNRGNIKR-YGWKKQYVVVSSKKILFYNDEQDKE-QSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILYANEGECRK-----DVEMEPVQ---QAEKTNFQNHKGHEFIPTLYHFPANCDACAKPLWHVFKPPPALECRRCHVKCHRDHLDKKEDLICPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNPPSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTS----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PRV2-1", "uniprot_id": "A0A8M9PRV2_DANRE", "id": "A0A8M9PRV2-1", "name": "Rho-associated protein kinase", "aln": "---------MEMSIGESLTARFEKIDAMLKDPKSEVNTDCLLDSLDALVYDLDFPALRKNKSIDDFLKRYKDTISKIRELRMKAEDYEVVKVIGRGAFGEVQLVRHKATRKVYAMKLLSKFEMIKRSDSAFFWEERDIMAFANSNWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTAEVVLALDGIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKDGMVRCDTAVGTPDYISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNALTFPEDSDISKDAKSLICAFLTDREVRLGRNGVDEIKRHGFFKNDQWTWENIRETAAPVVPELSCDTDTSNFDDIEEDRGEEETFPIPKAFVGNQLPFVGFTYYSNNLFSQESTIKTSDKRS-STKEDKSLLENLQKRIYQLEEQVHSEMQLRDEMEQKCRASNTKLDK----IMKELDEESNLRKSVEANMSILEKDKIMIQHRATEYQRKADQEAEKRRNLENEVSTLKEQLEDLRKISQN----NDKIAQLQNQLGEANDLLRAESDTVMRLRKSHTEMGKTMSQLESINRELQEKIRAAESVKQQLEKELLQLQTTLDTERRSCSQGSEEIRELQVRIMGLQEDNKNLKQSLTKVETERKHVQERCNILEKEKNSLEIDLNYKLKTLQQRLDQELTEHRITKAQLTDKYESIEESKSAAMHAVEQKVSEETTLRMRAESRVVEVEKQCSMLEFDLKQSVQKMEQLMKQKERLEDEVKDLRVQLEQETGKRVMSQNELKNWKMDSERLKGTEKQLKQEINAALENKRSVEFQLAQLTKQYRGNEGQMRELQDQLEAEQYFSTLYKTQVKELKDEIEEKNRQTQEALKRVQDLNSEKESLSAQLDLTMTKAESEQLARALQEEQYVELSQE-------YKKAVSRYKQEISEKDSTISQLEDSNKTLTKDVEILSKEKTEFNERIQAQEQEFAAEREELTNSIKANYEKALNIERTLKTQAVNKLAEIMNRKDMKDQKKRG---STTDLRKKEKENRKLQLELNQEKEKFNHMAFKYQKELNEMQAQWAEECTYRNELQMQLDSKESDIEQLREKLNDLQLRVDNSSVTSLQ-PDELDSNIAE---------------SRLEGWLAIPNRANIKR-YGWKKQYVVVSSKKILFYNDEQDKE-QSNPSMVLDIDKLFHVRPVTQGDVYRAETDEIPRIFQILYANEGECRK-----ETDVESVP---QGDKANCLPHKGHEFIPTLYHFPTNCEACSKPLWHVFKPPPALECRRCHVKCHKDHLDKKEDMITPCKVNYDVTSARDMLLLALSQDEQKKWIGHLGKKIPKTPPSTFARQSPRSMSVRSGANQSFRKNPKNVPGKPSRAQSILQAADTTSSTC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXE3-1", "uniprot_id": "Q9VXE3_DROME", "id": "Q9VXE3-1", "name": "Rho-associated protein kinase", "aln": "MPAGRETVTKQRSMDVERRRRANTLEREMRDPTSICNVDCLLDTVSALVSDCDHESLRRLKNIEQYAAKYKPLAMQINQLRMNVEDFHFIKLIGAGAFGEVQLVRHKSSSQVYAMKRLSKFEMMKRPDSAFFWEERHIMAHANSEWIVQLHFAFQDAKYLYMVMDFMPGGDIVSLMGDYDIPEKWAIFYTMEVVLALDTIHNMGFVHRDVKPDNMLLDSYGHLKLADFGTCMRMGANGQVVSSNAVGTPDYISPEVLQSQGVDNEYGRECDWWSVGIFLYEMLFGETPFYADSLVGTYGKIMDHKNSLSFPPEVEISEQAKALIRAFLTDRTQRLGRYGIEDIKAHPFFRNDTWSFDNIRESVPPVVPELSSDDDTRNFEDIERDEKPEEVFPVPKGFDGNHLPFIGFTYTGDYQLLSSDTVDAESKEANVANSGAASNNHGHGHNHRHRPSNSNELKRLEALLERERGRSEALEQQDAGLRQQIELITKREAELQRIASEYEKDLALRQHNYKVAMQKVEQEIELRKKTEALLVETQRNLENEQKTRARDLNINDKVVSLEKQLLEMEQSYKTETENTQKLKKHNAELDFTVKSQEEKVRDMVDMIDTLQKHKEELGQENAELQALVVQEKNLRSQLKEMHKEAENKMQTLINDIERTMCREQKAQEDNRALLEKISDLEKAH----AGLDFELKAAQGRYQQEVKAHQETEK---SRLVSREEANLQEVKALQSKLNEEKSARIKADQHSQEKERQLSMLSVDYRQIQLRLQKLEGECRQESEKVAALQSQLDQEHSKRNALLSELSLHSSEVAHLRSRENQLQKELSTQREAKRRFEEDLTQLKSTHHEALANNRELQAQLEAEQCFSRLYKTQANENREESAERLS-------KIEDLEEERVSLKHQVQVAVARADSEALARSIAEETVADLEKEKTIKELELKDFVMKHRNEINAKEAALATLKEAENELHKKLGQKAAEYEDLVQQHKKQQEELALMRSSKDEEITKLLDKCKN-EVLLKQVAVNKLAEVMNRRDSDLPKQKNKARSTAELRKKEKEMRRLQQELSQERDKFNQLLLKHQ----DLQQLCAEEQQLKQKMVMEIDCKATEIENLQSKLNETA----SLSSADNDPEDSQHSSLLS-----------LTQDSVFEGWLSVPNKQNRRRGHGWKRQYVIVSSRKIIFYNSDIDKHNTTDAVLILDLSKVYHVRSVTQGDVIRADAKEIPRIFQLLYAGEGASHRPDEQSQLDVSVLHGNCNEERPGTIVHKGHEFVHITYHMPTACEVCPKPLWHMFKPPAAYECKRCRNKIHKEHVDK-HDPLAPCKLNHDPRSARDMLLLAATPEDQSLWVARLLKRIQKSGYKAASYNNNSTDGSKISPSQSTRSSYKPYAVNVQRSATLPANSSLK----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . * :.:: ::**.* * ***** :.*** * *. :**: *.*::: :** :*.:***:.**:..:*:** ************:: :***** ******:**.*********.***.*** *:***.:**** :******::*****:*.**.:**:***** *** ******* **.***:************. ************:*. :* * ...*************:*** *. ***********:******.*:************.***:***:*:** : :**::** ** ****** **** *:::** * **:** *:::.:*::..****:**.* ** **:*:*.*. **.**:**.* **:***:**** .: : ....:.: :: . : : :: . . .*:: : : :: * . *:: : :::: : . .:: * **: : **. . :*.:** * *:: * : : :**: :* *:*: .*::** * :: ::*::.. :*:* ::*:. ::.. *. *:: : :. *.: :: :**: : *:. .: .* : : :: * :: :. :.: :.: : . ** : .*:::**: * * :**:. *: *: .: * **:: : ::.*:.** * :*:.: : *:* ***..* :* ::::* : .: .: * * **:** .** .**. : .*:. *:*:::*:.: * ** .* :*:**.. :: .: **** ****** ** *****.:* ::* *: ::::*:.*: :* *:::: ::*:** ***.: ** :* :* *. . : ::**. *: ::: *::::. * *.: * :: :: : ::* :.. ..:. :* . * ** *******:***:* . ::: .* :******* *:** **.**::***:: .*:* ::* .** :::: *:: .* ::**:*: ** : . * :. *. ...: * :****::**: * :* :***:***:***:*::***.: **. :.. ::**:.*::***.****** **::.***:***:***.** .:: : ::. : : ::.. ******: **:*: *:.*.*****:****.* **:**: * *::*:** .* : ***:.:* ********* . ::*. *: :* *:* *. . . : . : ..** *. * . : . ", "identical_positions": 530, "similar_positions": 442, "identity": "37.09%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100713-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZQV3-1", "uniprot_id": "A0A8I5ZQV3_RAT", "id": "A0A8I5ZQV3-1", "name": "", "aln": "MRPFQLDLLFLCFFLFSQELGLQRRGCCLVLGYMAKDKFRRMNEGQ----------------------------------VYSFSQQPQDQVVVSGQPVTLLCAIPEYDGFVLWIKDGLALGVGRDLSSYPQYLVVGNHLSGEHHLKILRAELQDDAVYECQA-----IQAAIRSRPARLTVLVPPDDPIILGGPVISLRAGDPLNLTCHADNAKPAASIIWLR--KGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQHPPLVNLSVEPQ-----------------------PVLEDNIVTFHCSAKANPAVTQYRWAKRGH-IIKEASGELYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFGPRMTSEPQSLLVDLGSDAVFSCAWIGNPSLTIVWMKRGSGVVLSNEKTLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESGTSGR--YTVETVNTEEGVISTLTISNIVRADFQTIYNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFLVLMATIVAFCCARSQRST-----------GGRPGISGRGTEQKARLRLPRRANLKGVVSAKNDIRVEIVHKEPASGREAEDHTTIKQLMMDRGEFQQDSVLKQLEVLKEEEKEFQNLKDPTNGYYSVNTFKEHHSTPTISLSSCQPDLR------PTGKQRVPTGMSFTNIYSTL-SGQGRLYDYGQRFVLGMGSSSIELCEREFQRGSLSDSSSFLDTQCDSSVSSSGKQDGYVQFDKASKASASSS-HHSQSSSQNSDPSRPLQRRMQTHV---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BR86-1", "uniprot_id": "KIRR3_MOUSE", "id": "Q8BR86-1", "name": "Kin of IRRE-like protein 3", "aln": "MRPFQLDLLFLCFFLFSQELGLQKRGCCLVLGYMAKDKFRRMNEGQ----------------------------------VYSFSQQPQDQVVVSGQPVTLLCAIPEYDGFVLWIKDGLALGVGRDLSSYPQYLVVGNHLSGEHHLKILRAELQDDAVYECQA-----IQAAIRSRPARLTVLVPPDDPIILGGPVISLRAGDPLNLTCHADNAKPAASIIWLR--KGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQHPPLVNLSVEPQ-----------------------PVLEDNIVTFHCSAKANPAVTQYRWAKRGH-IIKEASGELYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFGPRMTSEPQSLLVDLGSDAVFSCAWIGNPSLTIVWMKRGSGVVLSNEKTLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESGTSGR--YTVETVNTEEGVISTLTISNIVRADFQTIYNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFLVLMATIVAFCCARSQR------------------------------------NLKGVVSAKNDIRVEIVHKEPSSGREAEDHTTIKQLMMDRGEFQQDSVLKQLEVLKEEEKEFQNLKDPTNGYYSVNTFKEHHSTPTISLSSCQPDLR------PTGKQRVPTGMSFTNIYSTL-SGQGRLYDYGQRFVLGMGSSSIELCEREFQRGSLSDSSSFLDTQCDSSVSSSGKQDGYVQFDKASKASASSS-HHSQSSSQNSDPSRPLQRRMQTHV---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IZU9-1", "uniprot_id": "KIRR3_HUMAN", "id": "Q8IZU9-1", "name": "Kin of IRRE-like protein 3", "aln": "MKPFQLDLLFVCFFLFSQELGLQKRGCCLVLGYMAKDKFRRMNEGQ----------------------------------VYSFSQQPQDQVVVSGQPVTLLCAIPEYDGFVLWIKDGLALGVGRDLSSYPQYLVVGNHLSGEHHLKILRAELQDDAVYECQA-----IQAAIRSRPARLTVLVPPDDPVILGGPVISLRAGDPLNLTCHADNAKPAASIIWLR--KGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQHPPLVNLSVEPQ-----------------------PVLEDNVVTFHCSAKANPAVTQYRWAKRGQ-IIKEASGEVYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFGPRMTTEPQSLLVDLGSDAIFSCAWTGNPSLTIVWMKRGSGVVLSNEKTLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESGTSGR--YTVETISTEEGVISTLTISNIVRADFQTIYNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFLVLMATIVAFCCARSQR------------------------------------NLKGVVSAKNDIRVEIVHKEPASGREGEEHSTIKQLMMDRGEFQQDSVLKQLEVLKEEEKEFQNLKDPTNGYYSVNTFKEHHSTPTISLSSCQPDLR------PAGKQRVPTGMSFTNIYSTL-SGQGRLYDYGQRFVLGMGSSSIELCEREFQRGSLSDSSSFLDTQCDSSVSSSGKQDGYVQFDKASKASASSS-HHSQSSSQNSDPSRPLQRRMQTHV---------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PG27-1", "uniprot_id": "A0A8M9PG27_DANRE", "id": "A0A8M9PG27-1", "name": "", "aln": "----------------MPERSPPRRVKMILEVFLI---LWLTGHGV----------------------------------NAVFSQQPQDLVVVAGQPVTLPCSIPGYHGVVLWLRDGLALGVGRDLSGYPRYAVVGDHGSGEHHLRIQKVELMDDAVFECQA-----IQAAMRSRPARLTVLVPPDDPMITGGPVVSLRAGDPLNLTCHADNAKPAASIIWIR--NGEVLNGAMYSKTLLRDGRRESTVSTLYISASNIESGQKIICRASNKAVPNGKETSVTIDIQHLPLVNLSVEPQ-----------------------PVLEGNLVKFHCSAKANPPVTQYKWAKGGS-VIKEVSGDTYEVIVDHSFFTEPVSCEVTNPLGSTNISRNVDVYFGPRMAAEPQSLQVDLGSDAVFNCAWTGNPSLTIVWMKRGSGVVLSNENILTLKSVRQEDAGKYVCRAVVPRVGAAEKEVSLTVNGPPTISSTQTHQAPHGEKGQIKCFIRSTPPPDRIAWSWKETVLESGTSGR--YTVETVSTEDGVLSTLTMSNIVPADFQTIYNCTAWNSFGSDTEIIRLKEQGG--------SQDSLPVAVIIGVAVGAFVAFIVLMGTIGAFCCTRSQRKKSAHLCTEDAHLVMPTLPTSICAQQRELASKIKTENLKGVVSAKNDIRVEIVHKDHNAARESEEHSGMKQLMIERGEFQQESVLKQLEVLQEEEKEYQHIKDPTNGYYSVNTFKEHHGTPTTMAGNQTTELRRDPATATTGKQRVPTGMSFTNIYSTLGAGPNRLYDYSQRFVLGMGSSSIELCEREFQRGSMSDSSSFLDTQCDSSVSSYSKQDGYVQFDKDSKASASSSSHYSQSSSQNSDLTRPLQKRMQTHV---------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08180-1", "uniprot_id": "ICCR_DROME", "id": "Q08180-1", "name": "Irregular chiasm C-roughest protein", "aln": "--------------MLHTMQLLLLATIVGMVRSSPYTSYQN----------------------------------------QRFAMEPQDQTAVVGARVTLPCRVINKQGTLQWTKDDFGLGTSRDLSGFERYAMVGSDEEGDYSLDIYPVMLDDDARYQCQVSPGPEGQPAIRSTFAGLTVLVPPEAPKITQGDVIYATEDRKVEIECVSVGGKPAAEITWIDGLGNVLTDNIEYTVIPLPDQRRFTAKSVLRLTPKKEHHNTNFSCQAQNTADRTYRSAKIRVEVKYAPKVKVNVMGSLPGGAGGSVGGAGGGSVHMSTGSRIVEHSQVRLECRADANPSDVRYRWFINDEPIIGGQKTEMVIRNVTRKFHDAIVKCEVQNSVGKSEDSETLDISYAPSFRQRPQSMEADVGSVVSLTCEVDSNPQPEIVWIQHPSDRVVGTSTNLTFS-VSNETAGRYYCKANVPGYAEISADAYVYLKGSPAIGSQRTQYGLVGDTARIECFASSVPRARHVSWTFNGQEISSESGHD--YSILVDAVPGGVKSTLIIRDSQAYHYG-KYNCTVVNDYGNDVAEIQLQAKKS----------VSLLMTIVGGISVVAFLLVLTILVVVYIKCKKRTKLPP-------------------------ADVISEHQITKN--GGVSCKLEPGDRTSNYSD-----LKVDISGGYVPYGDYS-----THYSPPPQYLTTCSTKSNGSSTIMQNNHQNQLQLQQQQQQSHHQHHTQTT--TLPMTFLTNSSGGSLTGSIIGSREI-RQDNGLPSLQSTTASVVSSSPNGSCSNQSTTAATTTTTHVVVPSS----------MALSVDPRYSAIYGNPYLRSSNSSL--LPPPTAV--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W4T9-1", "uniprot_id": "Q9W4T9_DROME", "id": "Q9W4T9-1", "name": "", "aln": "MKRMRSSRLLVLPLILVLILTLLLQPIAVHAKSKKNKSSQSSHHGDSSSSSSSSSSSSGSSSAAASSANDESKPKGGDNGGQHFAMEPQDQTAVVGSRVTLPCRVMEKVGALQWTKDDFGLGQHRNLSGFERYSMVGSDEEGDFSLDIYPLMLDDDAKYQCQVGPGPQGEQGIRSRFAKLTVLVPPEAPKITQGDYLVTTEDREIELECVSQGGKPAAEITWIDGLGNVLTKGIEYVKEPLADSRRITARSILKLAPKKEHHNTTFTCQAQNTADRTYRSAKLLLEVKYAPKVIVSVVG----------GALAGG--------KIPEGAEVILSCQADANPHELSYRWFINDELMTGDFTTKMIIHNVSRQYHDAIVKCEVVNAVGKSEQSKKLDISFGPVFRQRPVSVEADLGATVSMRCDVAGNPEPEIEWISENSDQVVGVAAELKLK-VSSETAGRYFCKAVVNGFPEIGAEATLYVKRAPIITSHKVQFGGVGGRVKIDCLAFSIPKAEHILWSFEGKIINMSSADPDIYIFEEHHLPEGVRAALIIRDSKATHFG-KYNCTVMNSYGGDSLVITLLREPGN---------IPVLLVVMGSMFCVAIILMIVMIIIVYRKRRSRKKPMP-------------------------ADVIPEASRGGDKLNELKSELRSKAYDVEYSEAGGDGLAINLTQSPMPDVQMKGATLGVPLAGPVKFDERFSGDFGGDRYNRQCHIKNLKNQQETAYKGSPQANGYAH--YFEYALDYSPPGGEGAAVVVGSGGVGKLKNGGMNSATLPHSAAATVNGGGAGNGGGASLPRNQRHEIQQSQQSNGFLGQPLLQNGIDSRFSAIYGNPYLRTNSSLLPPLPPPSTANPAATPAPPPYHAARHGHAHHANGGLKHFVGGAVITTSPVGNVNINGGGGGGSTPSGGGGVGVGVAAGGSVSGSSSNLTASSNTLAATPLAGGGVGNSGQCAQSPSGQFILSNNGKGHTQKGPLATHV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: :*** ..* * *** * : * : * :*.:.** *:**.: :* :**.. .*:. * * * *** ::**. : .:** * *******: * * * : . ::: * : ..****.* *: . : .. * * * :* : * * ::. . . . .: *:* *.* :.:.: ::::: * * :.* : * * : * *.*** *:* . : . . * :. *.*** *.:*.:: *..:*: :.* : .* *: .*:*: . : * .**. * *:.. *. *:. *.:. * .* **:* *:* * :. : :: .* * * :.: . * :*.*: * * . :: *::: :. :. * . ** ::* : : .: ****. *.:*.* * * : . .: :.:: .: * : .:.:: : *.: . . .:. : :. : : . : . . . : : : . . ..* . : . . . : : . : . . . *. : . .: ** . : ::... * ", "identical_positions": 131, "similar_positions": 208, "identity": "12.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100714-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2GV87-1", "uniprot_id": "PTPRE_RAT", "id": "B2GV87-1", "name": "Receptor-type tyrosine-protein phosphatase epsilon", "aln": "MEPFCPLLLASFSLSLATAGQGNDTTPTESNWTSTTAGPPDPGTSQPLLTWLLLP--LLLLLFLLAAYFFRFRKQRKAVVNSNDKKMPNGILEEQE------------------------------QQRVMLLSRSPSGPKKYFPIPVEHLEEEIRVRSADDCKRFREEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHCRVILSQLDGIPCSDYINASYIDG-----YKEKNKFIAAQGPKQETVNDFWRMVWE---QRSATIVMLTNLKERKEEKCYQYWPD--QGCWTYGNIRVCVEDCVVLVDYTIRKFCIHPQ-LPDSCKAPRLVSQLHFTSWPDFGVPFT------PIGMLKFLKKVKTLNPSHAGPIVVHCSAGVGRTGTFIVIDAMMDMIHSEQKVDVFEFVSRIRNQRPQMVQTDVQYTFIYQALLEYYLYGDTELDVSSLERHLQTLH--GTATHFDKIGLEEEFRKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVILSMKRGQEFTDYINASFIDGYRQKDYFMATQGPLAHTVEDFWRMVWEWKSHTIVMLTEVQEREQDKCYQYWPTE-------GSVTHGDITIEIKSDTLSEAISIRDFLVTFKQPLARQEEQVRMVRQFHFHGWPEVG-IPTEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAEGLLD-----------------VFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFIDIFSDYANFK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49446-1", "uniprot_id": "PTPRE_MOUSE", "id": "P49446-1", "name": "Receptor-type tyrosine-protein phosphatase epsilon", "aln": "MEPFCPLLLASFSLSLARAGQGNDTTPTESNWTSTTAGPPDPGASQPLLTWLLLP--LLLLLFLLAAYFFRFRKQRKAVVSSNDKKMPNGILEEQE------------------------------QQRVMLLSRSPSGPKKFFPIPVEHLEEEIRVRSADDCKRFREEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHCRVILSQVDGIPCSDYINASYIDG-----YKEKNKFIAAQGPKQETVNDFWRMVWE---QRSATIVMLTNLKERKEEKCYQYWPD--QGCWTYGNIRVCVEDCVVLVDYTIRKFCIHPQ-LPDSCKAPRLVSQLHFTSWPDFGVPFT------PIGMLKFLKKVKTLNPSHAGPIVVHCSAGVGRTGTFIVIDAMMDMIHSEQKVDVFEFVSRIRNQRPQMVQTDVQYTFIYQALLEYYLYGDTELDVSSLERHLQTLH--STATHFDKIGLEEEFRKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVILSMKRGQEFTDYINASFIDGYRQKDYFMATQGPLAHTVEDFWRMVWEWKSHTIVMLTEVQEREQDKCYQYWPTE-------GSVTHGDITIEIKSDTLSEAISVRDFLVTFKQPLARQEEQVRMVRQFHFHGWPEVG-IPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAEGLLD-----------------VFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFIDIFSDYANFK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23469-1", "uniprot_id": "PTPRE_HUMAN", "id": "P23469-1", "name": "Receptor-type tyrosine-protein phosphatase epsilon", "aln": "MEPLCPLLLVGFSLPLARALRGNETT-ADSNETTTTSGPPDPGASQPLLAWLLLPLLLLLLVLLLAAYFFRFRKQRKAVVSTSDKKMPNGILEEQE------------------------------QQRVMLLSRSPSGPKKYFPIPVEHLEEEIRIRSADDCKQFREEFNSLPSGHIQGTFELANKEENREKNRYPNILPNDHSRVILSQLDGIPCSDYINASYIDG-----YKEKNKFIAAQGPKQETVNDFWRMVWE---QKSATIVMLTNLKERKEEKCHQYWPD--QGCWTYGNIRVCVEDCVVLVDYTIRKFCIQPQ-LPDGCKAPRLVSQLHFTSWPDFGVPFT------PIGMLKFLKKVKTLNPVHAGPIVVHCSAGVGRTGTFIVIDAMMAMMHAEQKVDVFEFVSRIRNQRPQMVQTDMQYTFIYQALLEYYLYGDTELDVSSLEKHLQTMH--GTTTHFDKIGLEEEFRKLTNVRIMKENMRTGNLPANMKKARVIQIIPYDFNRVILSMKRGQEYTDYINASFIDGYRQKDYFIATQGPLAHTVEDFWRMIWEWKSHTIVMLTEVQEREQDKCYQYWPTE-------GSVTHGEITIEIKNDTLSEAISIRDFLVTLNQPQARQEEQVRVVRQFHFHGWPEIG-IPAEGKGMIDLIAAVQKQQQQTGNHPITVHCSAGAGRTGTFIALSNILERVKAEGLLD-----------------VFQAVKSLRLQRPHMVQTLEQYEFCYKVVQDFIDIFSDYANFK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QJB7-1", "uniprot_id": "A0A8M9QJB7_DANRE", "id": "A0A8M9QJB7-1", "name": "Receptor-type tyrosine-protein phosphatase epsilon", "aln": "---MVLVLFLSVTTPQVTT-----------NATENNHGDPGPFNTHILSILLGLS-VLLLFLGLLTWYCLRLKNQRKAVITAVDKKVPNGILEEQEEYIDVDVDVDMDMDMDEDEDEDDLGWPSEEQQTVVLLPRSPSTSKTYLPIPVDNLEEEYRIRSADDGKLFREEYSSLPGGSIQGTCEEANKEENKEKNRYPNILPYDQSRVILTPMDGVTCSDYINASYIDG-----YKDKNKFIAAQGPKQDTTADFWRMIWE---QKSSTIVMLTNLKERKEDKCYQYWPD--QGCWTYGNVRVAVEDFTVLVDYTIRKFCVQYQ-ASDGSKSPRLVTQLHFTSWPDFGVPFS------PIGMLKFLKKVKQVNPSYAGPIVVHCSAGVGRTGTFIVIDAMIDMMHTEQKVDVFGFVSRIREQRSQLIQTDLQYSFVYQALLEYFLYGDTELDVSSLEGHLQKLH--NTNAPLDRVGLEEEFKKLTNMRIMKENMRTGNLPANMKKNRVLQIIPYDFNRVILSMKRGQEFTDYVNASFIDGYRQKDYYIATQGPLVHTVDDFWRMAWEWKCHSIVMLTELQERDQDKCFQYWPSE-------DSVTYGEFSVEIKGDTLCETFSLRDLVLTHTP-----EKQTRLVRHFHFHGWPEIG-IPAEGKGMIDIIAAVQKQQQQSGNHPIIVHCSAGAGRTGTFIALSNILERVKAEGLLD-----------------VFQTVKSLRMQRPHMVQTVEQYDFCYRVVQDFVDIFSDYANFK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25044-1", "uniprot_id": "PTP1_YEAST", "id": "P25044-1", "name": "Tyrosine-protein phosphatase 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------MAAAPWYIRQRDTDLLGKFKFIQNQEDGRLREATNGTVNS--RWSLGVSIEPRNDARNRYVNIMPYERNRVHLKTLSGN---DYINASYVKVNVPGQSIEPGYYIATQGPTRKTWDQFWQMCYHNCPLDNIVIVMVTPLVEYNREKCYQYWP-----------------------------------------------------------------------------------------------RGGVDDT-----------------------------------------------------------------------------------------------VRIASKWESPG------------------------GANDMTQFPSDLKIEFVNVHKVKDYYTVTD------------------------------------IKLTPTD-------PLVGP-----------------------------------VKTVHHFYFDLWKDMN-KPEEVVPIMELCAHSHSLNSR--GNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITERSRHSDRATEEYTRDLIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKYLNSLSVNQ----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VJ95-1", "uniprot_id": "Q9VJ95_DROME", "id": "Q9VJ95-1", "name": "", "aln": "---------MTAATGGGSSGAGGGKTGKHRSRSSARYDDVEKQQRKSRAIVSIPNTIKLSMLNSGLLSFERIKLEARDENNSLSKTIPN----------------------------------------------GPIDIRHFLK--LCDLRRKFPVLYKLEFQTAAKVES--------NTCRHALKKNNLEKNQNPKCIPYDYNRVVLEKVGGLQDSDYVNASYVDS-----LLKPNAYIVTQGPVEETVQAYWRMVWQ---ENISAIVMLTKTFDFAKVMCHQYWPPNMEVHEQYGDIFINIVREEQLANFHIRTFRLYKMNEKQEVTDERLILQFHYTEWYSHSCPFSNALLEFRRRVRLVVGNIIKDEDDMRGPILVHCSDGGGRSGVYMSIDANLELAEEEECFNVFGYLKKLRQSRKGLVENVEQYKFIYDTLEEHIICGKTWFPVSELSDRLKAKARRNSGTKMNEYQAEYDQICKQTPRFTIGDCAGGHRADNREKNRDVLCVPPDNFRPYLTSFQGNAFTDYINSVFVDGYTKPREYIVTEWPMKHTLGEFWSLVYDQECSAVVVLCQPPSQSQ-QYPSFWPNKSKMEKYGPVFSVHYVMSKSYTNIKQWEFKINKKIVSLTEMMAGVKAPTRTVQLFQLTCWPMGHKVPSSTNSLVYLMNMVEIWRNKVDYGPVCVVSPDGRSRAGVYCAANACIEQVIQHGEVD-----------------VFQAVKTVRRHRPQLVENMTEYKYCYDLVLHYVLHFLNKKE--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .* : . : : . : : : .* :*: : :* : ** * :.* **:****:. . . :*.:*** ..* :*:* :. .***:* : . *:**** * . : *: * :.. :: *:: : : .*: . *.. . .: *: * : * * . :: : . ..: *: * .. * .*:*.: * . :. . : : * * :* :* ::*:. :: : * . : ", "identical_positions": 52, "similar_positions": 92, "identity": "6.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100716-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3U3N6-1", "uniprot_id": "AP4AT_MOUSE", "id": "Q3U3N6-1", "name": "AP-4 complex accessory subunit Tepsin", "aln": "MAAVPPLRDRLSFLHRLPILLKGTSDDSIPCPGYLFEEIAKISHESLGSSQCLLEYLLNRLDSSSGHVKLKVLKILLYLCGHGSSSFLLILRRNSALIQEATAFSGPPDPLHGNSLYQKVRAAAQDLGSTLFSD-AVPQPPSQPPQ-IPPPAGMGAQARPLSALQGFGYTKESSRTGSAGETFLSTIQRAAEVVANAVRPGPDNPCTKGPLPYGDSYQPAVTPSASHTHPNPGNLLPGAILGARAVRHQPGQAGGGWDELDSSPSSQNSSCT--SNLSRASD--SGSRSGSDSHSGTSREPGDLAERAEATPPNDCQQELNLVRTVTQGPRVFLSREETQHFIKECGLLNCEAVLELLLRQLVGTSECEQMRALCAIASFGSADLLPQEHVLLLCRQQLQELGAGSPGPVTNKATKILRHFEASCGQQLPTLRLCAQPNSAAAPVGPADLLTSPVPAPGSQVFLQPLSSATVVPRS----------PVLFPSPNTLPPSALEEPSEVRTQLVCSSEQGTESEQRLENTDTPEDSSSPLPWSPNSLFAGMELVACP---RLP---------CHSS-QDLQTDLQKVTT-EAPVSEP-SAFAFLNM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96N21-1", "uniprot_id": "AP4AT_HUMAN", "id": "Q96N21-1", "name": "AP-4 complex accessory subunit Tepsin", "aln": "MAAAPPLRDRLSFLHRLPILLKGTSDDDVPCPGYLFEEIAKISHESPGSSQCLLEYLLSRLHSSSGHGKLKVLKILLYLCSHGSSFFLLILKRNSAFIQEAAAFAGPPDPLHGNSLYQKVRAAAQDLGSTLFSDTVLPLAPSQPLG-TPPATGMGSQARPHSTLQGFGYSKEHGRT--------------------------------------------------------------------AVRHQPGQAGGGWDELDSGPSSQNSSQN--SDLSRVSD--SGSHSGSDSHSGASREPGDLAERVEVVALSDCQQELSLVRTVTRGPRAFLSREEAQHFIKACGLLNCEAVLQLLTCHLRGTSECTQLRALCAIASLGSSDLLPQEHILLRTRPWLQELSMGSPGPVTNKATKILRHFEASCGQLSPARGTSAEPGPTAALPGPSDLLTDAVPLPGSQVFLQPLSSTPVSSRSPAPSSGMPSSPVPTPPPDASPIPAPGDPSEAEARLAES--RRWRPERIPGGTDSPKRGPSSCAWSRDSLFAGMELVACP---RLVGAGAAAGESCPDAPRAPQTSSQRTAAKEPPGSEP-SAFAFLNA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F390-1", "uniprot_id": "E7F390_DANRE", "id": "E7F390-1", "name": "", "aln": "---MVSILERLVFLQKVPTLMRATSDDESPCPGYLFEEISKISHESVGCCQCLLEYLLERLQVESCHVKLKVLKILLHVCGHGPPHFLTELRRNATFIQEVIVYSGPPDPIHGNALYQKVRSSAQELASLLFNDSMSPDSVSSPHKSMTHSVGMGSES-LRSGMQGFGSS--PGRKESTSGTLLDKIQKAAEVVASAVLPPTEHP---GLRLHDNHYHAVVAPSAAVEIAVPACAYNIQSHSHRTSHRCPGQAGGGWEETDSGHSSSHNSSQEIAEASQASMGRSSKSGGSGSHSGASRESGDLSERVEAIQLGDCGQETALINKLTSGSKVFLSREESQHFIKECSTLNCEVVVELLSRKLQDHTQIVQMRALCALACLMSSDFLSLDHIFNIIHKRLAQLSEGTTGPVANKATKLLRQFEALLGCVTNPR-FDRIGRSSSTNLSSSDQPSTSITIP----FISGQTG----------------------EPTTPVIPSEMAFTQGNSTAPGSHMNREQEEGEHRNTDTSKSSDP----SRLSLFSGMELVNRSKPVCLVEPVPVDAQPCGEATTDTDCALEKRTAGSSTSAEQLSAFSFLNL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :** **:::* *::.****. **********:****** *..********.**. .* * *********::*.**.. ** *:**:::***. .::*****:***:******::**:*.* **.* * . *.* . ..***::: * :**** : .*. : :: ********:* **. **.:.* :: *:.* *.. .**.****:***.***:**.*. .** ** *:..:* *.:.******:***** *. ****.*::** :* . :: *:*****:*.: *:*:*. :*:: : * :*. *:.***:*****:**:*** * . .::: ..:* : .:. * *:. :. * : .: :: .: * . . * .**:.: . . * ***:***** . * * .: : :: :: ... :* ***:*** ", "identical_positions": 205, "similar_positions": 149, "identity": "33.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100716-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L322-1", "uniprot_id": "A0ABK0L322_RAT", "id": "A0ABK0L322-1", "name": "", "aln": "MDGRDFAPPPPHLLSERGSLGHRSAAAAARLAPAG-PAAQPAAHFQPGKYFPSPLPMASHTASSRLMGNPPASSFMGSFLTSSLGSAASAHPNGPTSSPSEPAYRG--SHPATSQIWFSHSHEAPAYPRFSGSLASTFLPVSHLDHHGNSNVLYGQHRFYGTQKDNFYLRNLPPQPAILPANHNFHGVPRATPTHPIGSCSRDR--IEAASLQKGPKEFDRFLMGKELGKEKASKVAEGRERPVVEEESSKDRQK----LVPPMPAEGPCKETGPAPRGSCEGRPKHLTSCLLNTKVLNG----DMGKASMASCAGGMLGRPGTGVAAPG---RCAKEVSGPVEPGPAFSECLERRQMLHHAVSYTVPSGLPTGPPPPLSTGPAGSFP-------CLQLHAGPDGLCP-----------LQDKVSRDLKASGPTFVPSVGHLADKSH-SFQVTEACAVAGDGKDRHLDAAMAPDH-APYGVS----YAHLKAESKGERRPGGFEAALHPRLKGLEYLS----SGPEAPFPGLPKGNLDKGGYFELPTS-QDCARSNHQDPLGGKTTQACCTLDKVANKEAPAGPPG-------------------GQKVARIRHQQHLVAP-----EVESGGSGAESKRKSVELASLGYSG---HHMPPWGVQTGHDTSMAIIEERKGSAYLDPFGSGLQQAALLSQELPTPQ------DEVSAMKNLLKYSN-QALVVGQKAPFVGLGGLKA---------------------SCVQQEAK--FPATKGPGPVERPDCARSREHEAPTHGDGEVRQPPVGIAVALARQKDTVSRPDAAYNTNSGRQGRAAPTFKAAGGPRATHTLDLESEEERSRACEDRLGLP----GRELLLQDNKDLVEFARIHPSSSCPGDLPPHLMMQGGQ-LGGDPAPHPHPAHPHWLPRTRSPSLWMGGHSYGLG---HPALHQNLPPGFPASVPGSMPSVFPLPQDAATQLVILPSEPTPHTTPHTLAEVMDQASLWPPMYGARGPASHMQHPGQLPVYSRSQLLRQQELYALQHQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHRATQALELQRAAQFQVPCPHQPHQPEIQDNSAPPRSHADGPRTPLHVSHQAVGHRDTKVWPSEPLSPHPQQRKPEDRHMELEEAAREKAPKSTHKPVALTPMAKGTPSSTTAG--LVKLSPCCQSPTLK-----TPAS-CPTPPPRPSAPCTLPICPTGSPGPGSKLPSTKDKSEEGQRAGTDLTALEP-------------------------------DLPPR-LNPSTGVDFS---LPSDVHSSDLPDPKTMQTTTPGTRPEPTRTFLPGEPPPCSPRNLEEPGLLSRTRDATQDLAILPPPVEGGLPPGKAEDPSPLEGLQALKFGDLLEGGGTEATGQTNSTQGGTQNERTVDQGVPQPSLGATPQALEQVAGSPVALDKDEGPQKAPDVAQLQEEETQLEENGGDSEVDWGTPNHSHPPKALPGLDALVAATVDLGDLPDISLPDAQTPAASVPLGTAPQPHTSGIHGIALLSELADLEIQQQKSELALQAEDEDVLAFNLQHLATLATAWSLVEAASLDNSVASLQAPAADPDRGPRLTPRMQILQRKDTWAPKTKPVCPLKAAIDRLDTQEVEMRMQLAELQRRYKEKQRELARLQRR----REESSRSPARRGPGRPRKRKHSSSLPALRPGGQLARSDSKKAKAVRASLSLLCAELRGD---EPPRKRSKLEKSPYTGLQTASSEKVRCKKSCGPAELSSSMAHKVA-QLKPKVKSKGLPASLSAFQRKEAAPGGRIRKKLSRAKSVKVSGAARHPHPNGDSGREMPKFQTQPAVAVAHEAGNGYDSEDCQALLETEAAPREPGLVLHPG---AVLGPSPSSVVKMEANQKAKKKKERQGLLGACRLSSPE--------GEVKIKRRTVKTKVGPKLERAPGRRPPGAPGKKKAKGKAKTGLRAEPGNATSRDSLFNPTRTFACR--EEGSKLASERLKRATRKSAMLQPVLRRKNGALSIALSARNAKAILGKSRKLTKVNREAVSKQGQGRAVSRLLESFAVEDDFEFDDDDDSSFSDEEE---EEEEAGVQLSEEQSAALARSCTIHKEDLQDGLPVLIPKEDSLLYAGSVRTLQPPDIYSIVIEGERGNRQRIYSLEQLLQEAVLDVRPQSSRYLPPGTRVCAYWSQKSRCLYPGNVV----------RGASSDE-EDLDSVVVEFDDGDTGHIAVSNIRLLPPDFKIQCTEPSPALLVSSSCRRTKKAASESHPPSEAPTPSLSPKVQDGPETSKTPGKKSGCKDKAGKVDLLTSGAKSPTGASDHFLGRRGSPLLSWSAVAQTKRKAVAAAAA--GGKGPGVLQNLFQLNGSTKK-LRARDT-LFPMHS-----MAAPVFGNSFRADSFSSLASSYTPFLGG-AGAGLPGGAHKLLRAKKAERAEVEKAGRRRAGSEFLVKLDHEGVTSPKNKNCKALLMS-----------DKDFGPK-LGRPLASPSYTHPALIGKDKK--------GRAPVHPLHMGLALRKYP------LPCDSDCPSSYS------DEDEDGPGLATGVPSRFLTRLSMSSSSSGSSTSSSSGSVSTSSLCSSDNEDSSYSSDDEDP-TLLLQTCLTRPVPALLAPPEALRSKGSSPHAHAHAQRCFLSRAGVTGAGAGAGPGVS-KSKFKRKEALSFSKAKELSRRQRLPSVENRPKISAFLPARQLWKWSGNPTQRRGMKGKARKLFYKAIVRGKETLRIGDCAVFLSAGRPNLPYIGRIESLWESWGSNMVVKVKWFYHPEETKLGKRQSDGKNALYQSCHEDENDVQTISHKCQVVGR----EQYEQMMRGRK-YQDQQDLYYLAGTYDPTTGRLVTADGVPVLC------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UHR0-1", "uniprot_id": "BAHC1_MOUSE", "id": "Q3UHR0-1", "name": "BAH and coiled-coil domain-containing protein 1", "aln": "MDGRDFAPPP-HLLSERGSLGHRSAAAAARLAPAG-PAAQPAAHFQPGKYFPSPLPMASHTASSRLMGNPPASSFMGSFLTSSLGSAASAHPSGPTSSPSEPAYRG--SHPATSQIWFSHSHEAPAYPRFSGSLASTFLPVSHLDHHGNSNVLYGQHRFYGTQKDNFYLRNLPPQPTILPANHNFPGVPRATPAHPIGSCSRDR--IEAASLQKGPKEFDRFLMGKEVGKEKVSKGAEGRERPAVEEDSGKDRQK----LVPPMPAEGPCKEAGPAPRGSCEGRPKHLTSCLLNTKVLNG----DMGKASLASCAGGMLGRPGTGVAAPG---RCAKEVAGPVEPGPAFSECLERRQMLHHAVSYTVPSGLPTGPPPPLSTGPAGSFP-------CLQLHAGPDGLCP-----------LQDKVSRDLKASGPTFVPSVGHLADKSR-SFQVAEACAVAGDGKDRHLDAAMATDHGAPYGVS----YAHLKAEGKGERRPGGFEAALHPRLKGLEYLS----SGPEAPFPGLPKGGLDKSGYFELPTS-QDCARSNHQDPLGGKATQACCTLDKVANKEAPAGPPV-------------------GQKVARIRHQQHLVAP-----EVESGGSGAETKRKSVELASLGYSG---HHMPPWGVQTGHDTSMAIIEERKGSAYLDPFGSGLQQAALLSQELPTPP------DEVSAMKNLLKYSN-QALVVGQKAPFVGLGSLKA---------------------SCVQQEAK--FPATKGPGPVERPDCARSREHEAP-HGDGEVRQPPVGIAVALARQKDTVGRPDTAYNTNSGRQGRAAPTFKGAGGPRASHALDLESEEERSRACEERLGLP----GRELLLQDNKDLVEFARIHPSSSCPGDLPPHLMMQGG-----DPAPHPHPAHPHWLPRTRSPSLWMGGHSYGLG---HPALHQNLPPGFPASVPGSMPSVFPLPQDAATQLVILPSEPTPHTTPHTLAEVMDQASLWPPMYGARGPASHMQHPGQLPVYSRSQLLRQQELYALQ------QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHRATQALELQRVAQFQ--------------------------------------------------------RKPEDRHMELEEAAQEKTPKSTHKPVALTPMAKGTPSSATAG--LVKLSPCCQSPTLK-----TPAS-CPTPPPRPSAPCTLPICPTGSPGPGSKVPSTMDKSEEGQRAGTNLTTLEP-------------------------------DLTPG-LNPTAGLDLS---LPSDVHSSDLQDPKTMQTTTPGTRPEPPRTFLPGEPPPCSPRNLEEPGLLSRARDATQDLANLPPPVEGGLPPGKAEDPSPLEGLQALKFGDLLEGGGTEATGQTNSTQGGMQNERTVDQGAPQPPLGATPQALEQEAGSPAALDKREGPQKVPDVAQLQEEETQLEESGGDSEVDWGTPNHSHPPKALPGLDALVAATVDLGDLPDISLTDPQTPAASVPLSTAPLPHSSGIHGIALLSELADLETQRQKSELSMQ-EDEDVLAFNLQHLATLATAWSLVEAANLDSPVTSLQAPAADPDRGPRLTPRMQILQRKDTWAPKTKPVCPLKAAIDRLDTQEVEMRMQLAELQRRYKEKQRELARLQRRHDHEREESSRSPARRGPGRPRKRKHSSSLPALRPGGQLARSDSKKAKAVRASLSLLCAELRGD---EPPRKRSKLGKSPYTGLQSVSSEKVRCKKSCGQAELPSSVAHKVA-QLKPKVKSKGLPAGLGAFQRKEAAPGGRIQKKLSRAKSVTASGAARHPHPDGDSGREMHKFQAQPAVAVAHEAGSGYDSEDCQALLGTEAAPREPGLVLHPGSGVAVLGPSPSSVVKMEANQKAKKKKERQGLLGACRLSSPE--------GEVKIKRRTVKTKVGAKLERAPGRRPPGAPGKKKAKGKVKTGLRTEPGTATSRDTLFSPTRTFACR--EEGSKLASERLKRATRKSAMLQPVLRRKNGALSIALSARNAKAILGKSRKLTKVKREAVSKQGQGRAVSRLLESFAVEDDFEFDEDD-TSFSDEEE---EEEEAGVQLSAEQSAALARSCTIHKEDLQDGLPVLIPKEDSLLYAGSVRTLQPPDIYSIVIEGERGNRQRIYSLEQLLQEAVLDVQPQSSRYLPPGTRVCAYWSQKSRCLYPGNVV----------RGASSDE-EDLDSVLVEFDDGDTGHIAVSNIRLLPPDFKIQCTEPSPALLVSSSCRRTKKAANEGHPPSEAPTPSLSPKVPDGPETSKTPGKKSGSKDKAGKVDLLTSGAKSPTGASDHFLGRRGSPLLSWSAVAQTKRKAVAAAAAAAGGKGPGVLQNLFQLNGSTKK-LRARDT-LFPMHS-----MATPVFGNSFRADSFSSLASSYTPFLGG-AGAGLPGGAHKLLRAKKAERAEAEKAGRRRAGGEFLVKLDHEGVTSPKNKNCKALLMS-----------DKDFGPK-LGRPLSNPSYAHPALIGKDKK--------GRAPVHPLPMGLALRKYP------LPCDSDCPSSYS------DEDEDGPGLATGVPSRFLTRLSMSSSSSGSSTSSSSGSVSTSSLCSSDNEDSSYSSDDEDP-ALLLQTCLTRPVPALLAPPEALRSKGSSPHAHTHAQRCFLSRAGVAGAGAGASPSGS-KSKFKRKEALSFSKAKELSRRQRLPSVENRPKISAFLPARQLWKWSGNPTQRRGMKGKARKLFYKAIVRGKETLRIGDCAVFLSAGRPNLPYIGRIESLWESWGSNMVVKVKWFYHPEETKLGKRQSDGKNALYQSCHEDENDVQTISHKCQVVGR----EQYEQMMRGRK-YQDQQDLYYLAGTYDPTTGRLVTADGVPVLC------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P281-1", "uniprot_id": "BAHC1_HUMAN", "id": "Q9P281-1", "name": "BAH and coiled-coil domain-containing protein 1", "aln": "MDGRDFAPPP-HLLSERGSLGHRSAAAAARLAPAG-PAAQPPAHFQPGKYFPSPLPMASHTASSRLMGSSPASSFMGSFLTSSLGSAASTHPSGPSSSPPEQAYRG--SHPTTSQIWFSHSHEAPGYPRFSGSLASTFLPVSHLDHHGNSNVLYGQHRFYGTQKDNFYLRNLPPQPTLLPANHNFPSVARAAPAHPMGSCSRDRDRGEAGSLQKGPKDFDRFLVGKELGREKAGKAAEGKERPAAEEDGGKERHK----LVLPVPADGHCREGGPAPRGACEGRPKHLTSCLLNTKVLNG----EMGRAALASCAGGMLGRPGTGVVTSG---RCAKEAAGPPEPGPAFSECLERRQMLHHTASY-------AGPPPPLST-AAGSFP-------CLQLHGGPDGLCP-----------LQDKAPRDLKASGPTFVPSVGHLADKGR-PFQAAEACAVAGEGKDRHLEGTMAPDHAAPYGVS----YAHLKAEGKGERRPGGFEAALNPRLKGLDYLSS---AGPEASFPGLPKSGLDKSGYFELPTSSQDCARPGHQDPLGGKAPQACCTLDKTVGKEAPAGPPG-------------------AQKVARIRHQQHLMAA-----EVEQGGIGAEAKRKSLELASLGYSG---PHLPPWGVQAGQGTAMAISEERKAGAYLDPFGSGLQQAALLPQELPAPP------DEVSAMKNLLKYSS-QALVVGQKAPLVGLGGLKA---------------------SCIQQEAK--FLSSKGPGQSERPDCARSREHDTT-HGDGEVRQPPVGIAVALARQKDTVSRSEAAYGTNTARQGRAAPAFKGGGGPRSTHALDLEAEEERTRLCDDRLGLA----SRELLLQDSKDRVEFARIHPPSSCPGDLAPHLMMQSGQ-LGGDPAPHTHP-HPPWLPRTRSPSLWMGGHSYGLG---HPALHQNLPPGFPASVAGPVPSVFPLPQDAPTQLVILPSEPTPHSAPHALADVMDQASLWPPMYGGRGPASHMQHPGQLPVYSRPQLLRQQELYALQ-----------------------------------QQRAAQFQ-----------------------------------------------------------------RKPEDQHLDLEEPAQEKAPKSTHKPVALTPTAPGAP-SPAAG--PTKLPPCCHPPDPK-----PPAS-SPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPVARAHSVAHAGLEFLASNDPSTSASQSFGITDLPPGYLRPMAGLGFS---LPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREATQDLAATPYPTERG-PQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGAREERSREEGEQGPSSGASSQVLEQRAGSPGALE-DEGEQPAPEEDELEEDELGQQSMEDSEEDCGGAPDNSHPPRALPGLDALVAATINLGDLPSDSPPDPQPPAASGPPSTVPLPHSSGIHGIALLSELADLAIQRQRSERTVPEEEEDVLAFNLQHLATLATAWSLVEAAGLDSSTAPAQPPTANPCSGPRLTPRMQILQRKDTWTPKTKPVCPLKAAIDRLDTQEVGMRVRLAELQRRYKEKQRELARLQRKHDHERDESSRSPARRGPGRPRKRKHSSSLPAPRPTGPLPRSDGKKVKAVRTSLGLLCAELRGGSGGEPAKKRSKLERSVYAGLQTASVEKAQCKKSSCQGGLAPSVAHRVA-QLKPKVKSKGLPTGLSSFQQKEATPGGRIREKLSRAKSAKVSGATRHPQPKGHGSRETPRCPAQPSVAASQEAGSGYDSEDCEGLLGTEAPPREAGLLLHTGASVAVLGPSPSSVVKMEANQKAKKKKERQGLLGACRLSSPE--------SEVKIKRRSVKAKVGTTLERAPGQRPPGALGKKKAKGKAKGSLRAEPGATPSRDALFNPSRAFACR--EEGSQLASERLKRATRKGTVLQPVLRRKNGALSITLATRNAKAILGKGRKLSKVKHKAG-KQGKGRAVSRLLESFAVEEDFEFDDNS--SFSEEEEDEEEEEEDSGPLSAEQSAALARSCAIHKEDLRDGLPVLIPKEDSLLYAGSVRTLQPPDIYSIVIEGERGNRQRIYSLEQLLQEAVLDVRPQSSRYLPPGTRVCAYWSQKSRCLYPGNVV----------RGASGDEDEDLDSVVVEFDDGDTGHIAVSNVRLLPPDFKIQCTEPSPALLVSSSCRRTKKVSSEAPPPSEAATPSLSPKAQDGPEALKTPGKKSISKDKAGKAELLTSGAKSPTGASDHFLGRRGSPLLSWSAVAQTKRKAVAAASK-----GPGVLQNLFQLNGSSKK-LRAREA-LFPVHS-----VATPIFGNGFRADSFSSLASSYAPFVGG-TGPGLPRGAHKLLRAKKAERVEAEKGGRRRAGGEFLVKLDHEGVTSPKNKTCKALLMG-----------DKDFSPK-LGRPLPSPSYVHPALVGKDKK--------GRAPIPPLPMGLALRKYAGQAEFPLPYDSDCHSSFS------DEDEDGPGLAAGVPSRFLARLSVSSSSSGSSTSSSSGSVSTSSLCSSDNEDSSYSSDDEDP-ALLLQTCLTHPVPTLLAQPEALRSKGSGP--HAHAQRCFLSRATVAGTGAGSGPSSSSKSKLKRKEALSFSKAKELSRRQRPPSVENRPKISAFLPARQLWKWSGNPTQRRGMKGKARKLFYKAIVRGEETLRVGDCAVFLSAGRPNLPYIGRIESMWESWGSNMVVKVKWFYHPEETKLGKRQCDGKNALYQSCHEDENDVQTISHKCQVVAR----EQYEQMARSRK-CQDRQDLYYLAGTYDPTTGRLVTADGVPILC------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6Z3-1", "uniprot_id": "A0ACD6B6Z3_DANRE", "id": "A0ACD6B6Z3-1", "name": "", "aln": "MEGRDFAPPP-HLLAERGALVHR---AASRITPAGHTTVQHPGHFQPGKYYPSHIPMPPHSGSG-LIGNSSAS-FMGTFLASSLGSPP-SHPSGPPSSPSSPPYRSGPHSTAPSQIWFPHSHEAPGYPRFSGSLAPTFLPMSPLDHHGNSSVLYGQHRFYDTQKD-FYLRSLPSQPHLLSANHSLPPLSRTAPAHPLDSCSRER---EPGSTVSQKS-------SKETGVAERRVGPGGKEKEKSKQESKQDRHHGPPTLHHHHQHHPQHHPQGLEDDFRHKDDPKHLSSCLLSTKTQNGSDPGAATRGSLPSCVGPGASSLGTGRQTSGDSHCCKEGVSGEMRISEPASDCLRHSAMLGHAHPMP----YSMPPPLGLGSAVGGSWLHPNHPHHHHPHHPHAELFCPPPPAPLTMPTAQEKSLGRDSEVTGPTFVPSVGPLGDKISGPFQLGNHHCRGVGGGMIAVGGSAGKETKTPERSSSGSRAANLLPQNSCQRKSSQQQHAYGKADKSPDWPPGPHLRTNEVQHSQNQHTHSARSCSLDSSEESDAFRPSLPQGTKGGHQAKSSIYASTPPFRDCSHSGPSNRASSEGKGATEVECTQKSSQRVARIRHQQHRASTGGQGPEMEPNSTTQDKRKMDMESASQGYGGNRTGTHPSWEVRGPQPRPDEEPHKAYNSLGAASQTSRVDQGPLPPLTAPQEATLGPQGPESNAMRNLMKYSSQQPLLFTQKSPFGGLGCLKQGAVAGERSERNERSDKSGNGSSCALQEGKQTLPPRRASSSGENERSERVGKDSGEAQGEGEVRQPPVGIAVAVARQREPPCRLPDGHPTHS-HHSRVMPSMKGIGHP--MYPLEREMDEERKRVCEEQLGLSPFDRERELLLRENKDRVEFARIHPSSSCHGDLTSHLIVPGGSQLGTEPSAHAHPTHHHWMPRTGSPSLWMG-HSYGLS---HAALHQNLTPGFSTTMPSPLQPVLPLPQDPSAALVVLPTEPVAHPATHHL-DVMEQQGLWPPVYGARGPTSHMQHP---AVYSRSQFLRQQELYALQ------------------------------QHQHQQHRAAQAMELAHRHSHS-------------------------------------------------------QRKPEDPPIDLVEGPSEPHAPKHTKPFSVGPSPKPPPSSSSPGGCASRLSPCCRSPAPRSHLKSTPCTPCPEPSPAVAAPRSPALSPHSTPHHLPKPAESQDKRGEGQPPQDYPQSLEP-------------------------------DLPPGYTYPAIAMGYKGGPSPQEVQLAEHADLEAEQAEPAEPAPRPHPLSPKGEEPVCHTG-VGSPIRISKEIEDVEEEGGVIE-EDGQVDEGQVDATLSQTSLCPTSDTSVAEPFSDKATAIPNSQTCGIVS--------PAPAEENNERDMDLQVPMIAPLTTTQNLQSVEPTKHDLDRTVEDGCTPPTNSSTPPLSPCPVPSDLGNQYPGSCIWSLELLIAAALCATRDARMAMSVPVSGNAVAPN---YGIELLSELAELEQSQQQRN-NTGENDDDMLTFDLQSLATLAAARALELAP-------PIPADSTPPLR------RILNLRKKCKWTPRSEPVCPVKATMETLDQEELAMRVRLAELQRRYKEKQRELAKLQRKHDHQKEETARSPARRGPGRPRKRKSTSAPPIPTDAPKKVKSAG-----AGAGPGLMTAEDLAG-GGDRKRKKKRMTGGPYHHLTST-QMKAHCRPRGRPRLLSTKFKQKACSQLKQKAKAKRGSRLVNLLCHRESKTQSTVPEHQSAKEEHAHNNKTGEQGDTAGSGTAVQQDSDGKRSVMKRGARS------KAILSSTPLPTRTQQLLCNTAMTDSKLEATEKGISDTEEEDDGIYDSE-EGAEGIKNLSSKEQLSGAGRPSQCSIVKLEANQKAKNKTERQ-GFGSMNVSVTKEEMKRRKAPCRPAQVCADHNHSELDEDRRLTGPKWREGSRENTFDHTRVLKTSPTPRERTTRKSAVLLGKRKSCWLQALSSQYDDISWSRRIRNKQQAKGRAVSRLLESFAADEGFQIDDDS--SFSEGEE-EEEEEEEEPELMGSALPALP-NCILTKEILRDGLKVLISKEDELLYAAYVHTLDLPDIYSVVVEGERGNRPRIYSLEQLLQEAVLDVQPETVETLMAGTRVCAYWSERSRCLYPGYVR----------RGGPGEE-QKEGSVMVEFDDGDRGWISLSSIRLLPPGYQVHCAEPSPAHLISPSCRRRKTSTQEKITQQADASNERS---------SNTEPRKSAVKAKPGRPKSVNASSKS--GASENMT-ETASPLLSWPVATMSRRKPS---------------MDLFQFNGLTKKALKGKESDMFPLLSSTMTTPAKGIFSTSFEVDSFSSIANGCTSFGNQQLAPGLPP-SHKVVPGSRCRKIGDRK--------EFLVKLDHEGVTSPKTKNGKALLLLGNPELQRSGRMEKGFGAKGIGELTSTMGYSQSVLLVKDAKRNSCHLLKGSSDMRKHPQGLGLSEYTDYG---PNCHSDCLSSYSDMDEDEDEEEDARRAAMRTTGRFLSRLSVSSSSSGSSSASSSGSLSSSSVCSSDN-DSSYSSDEEEASRLLLQGCLSS--HHTLLQQQQHSDPPTAPPRHTFGAKTMSISNSKAAVNSSTGKPPKRKEIANSSSVVQSKSSKDFPKKQKMQSSEGPPNSSAFMPGRQLWRWSGNPTQRRGLKGKARKLFYKAIVRGKDTVRVGDCAVFLSAGRPHLPFIGRIESLWESWSSNMVVKVKWFYHPEETKLGKRHRDGKHALYQSSHEDENDVQTISHKCQVVSR----AEYERLSRIRKPNSNGQDLYYLAGTYDPTSGQLVTAEGESIIC------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q3LHL9-1", "uniprot_id": "WGE_DROME", "id": "Q3LHL9-1", "name": "Protein winged eye", "aln": "-----------------------------------------MATFNPGASSSAADVLSATTATATFLVP---------------TTAAVSHPGAHTAHLQLDQFGGFSAATATPLQHHHHQQTNSSYTFVQIKREPCQVSEISSNNCHQQQQQHHQHHQHQVQHQGLSSASMTASSKTMSSSTLTTLVKIEAPSPKVSELEKSTG------------------NSVPIGIAVARKRPQEALVPAINTPATLPLQP-------PLNKDLNCFGIRVADLG--------ATSCGNLYFTGNG----DLMTTGTATAEELALSAAGVNRAPST---FWQYPNALPIESVISMSPATVGLQYSREASRGQ----VVLLPAGPTALDP------------------------------------FQQAAAAAAFVWPSAYIP------------------QAPAPGGHSAAAAAAAASLQPTPNLSS-------------------------------------------------LPNFIFPSMGGHQALSTTPSYASTLQLYLAAAATATGSSTMCQHSNQQTSTTTTN-----------------------------------------------------STINLSLAAGSG---------VTQSGNAASSLSSSSSLSASSSRFLSLATGQTGIPSLLSLPPP--------------------------------------------------------------------------------------------------TGLKEEYPMPLALPPLVPLEAARDKEQALNLMRLPTPPTSATME-------------------------------------------------------PSSLGHATPHHLFQSGAMATPTPALLNLSMHGNGGELPAATPLPAVSDEAALNYKLHAPLTPQTPPRLADIPVSGSTQLLPQMQDVNIQTDTPVCSEDESFPGS-------------------------------------------------------------------------------------------------------------------------------------------------------------AKPQDPAAEAFPPPTHVQPLELTKPSEASHTQPTECHTQTEP----------------------------SDIPSASQEESAEQTPPEPIETMTQATQADQTSPEDLTGLELLSNIST----------------------------------------------------NSKPLVRVKQEPVEHIEQPAPQPQPVNIMPSEPTLPMPPMLEMEP-------------------------TSEREPLGGLKLLCALAEQRIQEEVVQGSSLFATPSSR-------------------------TPTPTSLALGTTAATPPIFEAKSCYAFGQSQGSVFPSSTSSFQMP---LSSPGFPSMQGIELPTTSAGIVAELTPVKRKKHKHSKSSGSDSRKSARCSKKSKKKRHHSSSRQQFSAPAEEDLDLQDDQLQSELR------------------------------------------------NALHAVDPSYAQRFGQEVFSIMDNSMRMRLAKITRQYRKKKRKLDEISKHKKKKKCSKQQLELQQQQASQQAVQPSSALQQPQ-----------------------------------------------MTLSSVLGTSSPLRDYKFPKFSSSNLQASSFLRFPDKTHSFPPPPSLQQSQPEPNP------------------------------------------------------------LPSSSSPSTSSFVRLEPSALDAAVAIAPTTSSTSTSGSP------------------------------------STKQVASARKQRKMKASTVGAAGEQTAATEAKR------------------------------------------------------------------------------------------------------------------------------------------RFSAIDRELQLTSEHLYRDETRVLTDMGGLFYAGVMKPLRPPDVYSITLDGERGNKSHVMSREDILKDTILEVAPKSVESVPVGTRLCAYWSQQYRCLYPGRAIDSEQVVDGTASSATNAATTAPDFVSVEFDDGDSGRIRLQNIRMLLSDYPIAEYNDNPLYSVG-------------------------------------KQKRSALRGGESGPGGVTQDHLTVPGCEDSHSHHSLG-----------------------------------------------------------------------MSSDNTTSLAATMELFTQR------------------------------------------------------------------------------------------------------------------------------------------------------SEKKRLKKSLKKMSKAQNGVSPATATNGGADAAALG----DGVSAEDAARKHHKHKKRKKHKKHHRKNGSEEQEQQVVQQDYSAAGQEATEAPSTEMSSATSSRVKVEVKVKTEQLEMEEEESASNLMSEISDEAKGDDLVEHNNSKGSSKIAAFLPERQLWGWYGTAYRKAGVKGRARKQFYKTIKRGKETITVGDSAVFLSTGRPDRPYIGRIESMWETTTGNKVVRVAWFYHPEETTGCPKLKFPG-ALFESPHEDENDVQTISHRCEVLQFGSYFEKFGADSKQYQSIYDNNDTYYLAGHYNPRLQVLKLQDDIPTLEELQDTNTTTTTTETTTED", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:** .: :.. :.:. :: :.. :**.. .: : . .:.. . *.: ..*. .. . . :. :: :.. : **: : .*:: : .:.... :.:. : :*: :.. .:. . * . : . : . :** . ** . .:. . *.. .. : . . * . .: *. . :. . .:::* . . * .: . :* * : : . .. . .. :: . . :: : . .* .: : . . . * : . * .: *: :*:. :. . . .::: .*. *. ..* :. .* *: . * . :..* .. .*. *..* : .* :. . ::* ** . . **:* : . . . . ** : : * : : * . .: .: :. *. .. .. : . : . . *.* . .* .: * : * :: . . . .* . . .. . : . . * . . . . :. . . ::* * :*: . .* . : : :. : **::**:: *:*::*:*:* .:.:: : .. : :: . : : :*: * :. . : .... :: *.:: . : . * : .. : ... : : : . . .: . :* . .. : . * .*: . : .* * . ::.. . *:**. ::.* **:**:.::*****: :: * *::*::::*:* *:: . : ***:*****:: ****** . .... . * ******* * * :..:*:* ..: : : .* :. ::* : . :. . : *..: . . : *. :*:* * .::. : .: :* ::::.*.: ::: * ..:.:.* . :. .... : : : : .. : . . : :. . . .. . . . :. .: :**:* **** * *.. :: *:**:*** ***:* **::*: :**.*****:***. *:******:**: .* **:* ********. : **::* ************:*:*: :: : : : :* ***** *:* * :. . : ", "identical_positions": 214, "similar_positions": 472, "identity": "7.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100716-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L4W7-1", "uniprot_id": "A0ABK0L4W7_RAT", "id": "A0ABK0L4W7-1", "name": "", "aln": "MMTVPLQKEAQRAAAPLRPHCQSLCSDSLSSFLAVVMDDDDDSCLLDLIGDPQALNYFLHGPSSKSSG-DDVTNAGYSAANSNSIFANSTNADPKSSLKGVSNQLGEGPSDGLPLASSLQFLEDELESSPLPD----LSEDQPFDILQKSLQEANITEQTLAEEAYLDASIGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTHVPVGASFASNTVGVQHGFMQHVGISVPSQHLPNSSQISGSGQIQLIGSFG-NQPSMMTINNLDGSQIILKGSGQQAPSSVSGGLLVHRQTPNGNSLFGNPTSSPGAQPVTVPFNSTNFQASLPVHNIIIQRGLAPNSNKVPINIQPKPIQMGQQSTYNVNSLGLQQHHVQQGISFASASSPQGSVVGPHMSVNIVNQQNARKPVTSQAVSSAGGSIVIHSPMGQPHTPQSQFLIPTSLSVSS-NSVHHVQTINGQLVQTQPSQLISGQVASEHVMLNRNSSNMLRTNQPYAGQMLNNQSAAVQLVSGQTFATSGSPVIVNHASPQIVGGQMPLQQASPTVLHLSPGQSSVSQGRPGFATMASVSSMSGPARFPAVSSASTAHPTLGPAVQSGASGSNFTGDQLTQANRTPVPVSVSHRLPVSASKSPSTLSSTP--GTQQQFFCQAPKKCLNQTAPIPTPIPTSKTTDSLRQPQIPGLLSTALPGQDCGSKIMPAPLGTTQPQQENSVGSSPSQTAVQVDSHSG-QKRPAAKQLTKGAFILQQLQRDQAHAVTPDKSQFRSLTDTVQRLLSYHVCQGSMPTEEDLSKVDSEFEEVATQLLKRTHAMLNKYRSLLLEDAMRINPSAEMVMIDRMFNQEERASLSRDKRLALVDPEGFQADFCCSFKLDEAAPETPLDRSDQHRSKTSS-LHQVPRAQSRDRAKPGVAEATNHDQFHLVPNHIVVSAEGNISKKSEGHSRTLKFDKGVLGQYRGPPEDKGGRRDPAKASGCSPGPEGHRKTLPRPDHGSESKLPGILASSHMEMPCLDSFQDKALRNSPKNEVLHTDIMKGSGEPQPDLQLTKSLEKTFKNILELKNAGR-PQNDPAASGAVDLDFPSFSPMASQENCLEKFIPDHSEGVVETDSILEAAVNSILEC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CHH5-1", "uniprot_id": "BICRL_MOUSE", "id": "Q8CHH5-1", "name": "BRD4-interacting chromatin-remodeling complex-associated protein-like", "aln": "------------------------------------MDDDDDSCLLDLIGDPQALNYFLHGPSSKSGS-DDVTNAGYSAANSNSIFANSTNADPKSALKGVSDQLGEGPSDGLPLASSLQFLEDELESSPLPD----LSEDQPFDILQKSLQEANITEQTLAEEAYLDASIGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTHVPVGASFASNTVGVQHGFMQHVGISVPSQHLPNSSQISGSGQIQLIGSFG-NQPSMMTINNLDGSQIILKGSGQQAPSNVSGGLLVHRQTPNGNSLFGNSTSSPVAQPVTVPFNSTNFQASLPVHNIIIQRGLAPNSNKVPINIQPKPVQMGQQSAYNVNNLGIQQHHAQQGISFAPTSSPQGSVVGPHMSVNIVNQQNTRKPVTSQAVSGTGGSIVIHSPMGQPHTPQSQFLIPTSLSVSS-NSVHHVQAINGQLLQTQPSQLISGQVASEHVMLNRNSSNMLRTNQPYSGQMLNNQNTAVQLVSGQTFATSGSPVIVNHASPQIVGGQMPLQQASPTVLHLSPGQSSVSQGRPGFATMPAVSGMAGPARFPAVSSASTAHPTLGPTVQSGAPGSNFTGDQLTQANRTPAPVSVSHRLPVSASKSPSTLSNTP--GTQQQFFCQAQKKCLNQTS----PIPTSKTTDGLRPSQIPGLLSTALPGQDSGSKIMPATLGATQAQPESSVGSSPSQTAVQVDSHPG-QKRPAAKQLTKGAFILQQLQRDQAHAVTPDKSQFRSLNDTVQRLLSYHVCQGSMPTEEDLRQVDNEFEEVATQLLKRTQAMLNKYRFLLLEDAMRINPSAEMVMIDRMFNQEERASLSRDKRLALVDPEGFQADFCCSFKLDEAVPETPLDRSDQHRSKTSS-LHQVPRAQSRDRAKPGMAEATNHDQFHLVPNHIVVSAEGNISKKSEGHSRTLKFDRGVLGQYRGPPEDKGGRRDPAKVSRCSPGPEGHRKSLPRPDHGSESKLPGVLASSHMEMPCLDSFQDKALRNSPKNEVLHTDIMKGSGEPQPDLQLTKSLEKTFKNILELKNSGR-PPSDPTASGAADLDFPSFSPMASQENCLEKFIPDHSEGVVETDSILEAAVNSILEC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AI39-1", "uniprot_id": "BICRL_HUMAN", "id": "Q6AI39-1", "name": "BRD4-interacting chromatin-remodeling complex-associated protein-like", "aln": "------------------------------------MDDDDDSCLLDLIGDPQALNYFLHGPSNKSSN-DDLTNAGYSAANSNSIFANSSNADPKSSLKGVSNQLGEGPSDGLPLSSSLQFLEDELESSPLPD----LTEDQPFDILQKSLQEANITEQTLAEEAYLDASIGSSQQFAQAQLHPSSSASFTQASNVSNYSGQTLQPIGVTHVPVGASFASNTVGVQHGFMQHVGISVPSQHLSNSSQISGSGQIQLIGSFG-NHPSMMTINNLDGSQIILKGSGQQAPSNVSGGLLVHRQTPNGNSLFGNSSSSPVAQPVTVPFNSTNFQTSLPVHNIIIQRGLAPNSNKVPINIQPKPIQMGQQNTYNVNNLGIQQHHVQQGISFASASSPQGSVVGPHMSVNIVNQQNTRKPVTSQAVSSTGGSIVIHSPMGQPHAPQSQFLIPTSLSVSS-NSVHHVQTINGQLLQTQPSQLISGQVASEHVMLNRNSSNMLRTNQPYTGPMLNNQNTAVHLVSGQTFAASGSPVIANHASPQLVGGQMPLQQASPTVLHLSPGQSSVSQGRPGFATMPSVTSMSGPSRFPAVSSASTAHPSLGSAVQSGSSGSNFTGDQLTQPNRTPVPVSVSHRLPVSSSKSTSTFSNTPGTGTQQQFFCQAQKKCLNQTS----PISAPKTTDGLRQAQIPGLLSTTLPGQDSGSKVISASLGTAQPQQEKVVGSSPGHPAVQVESHSGGQKRPAAKQLTKGAFILQQLQRDQAHTVTPDKSHFRSLSDAVQRLLSYHVCQGSMPTEEDLRKVDNEFETVATQLLKRTQAMLNKYRCLLLEDAMRINPSAEMVMIDRMFNQEERASLSRDKRLALVDPEGFQADFCCSFKLDKAAHETQFGRSDQHGSKASSSLQPPAKAQGRDRAKTGVTEPMNHDQFHLVPNHIVVSAEGNISKKTECLGRALKFDKVGLVQYQSTSEEKASRREPLKASQCSPGPEGHRKTSSRSDHGTESKLSSILADSHLEMTCNNSFQDKSLRNSPKNEVLHTDIMKGSGEPQPDLQLTKSLETTFKNILELKKAGRQPQSDPTVSGSVELDFPNFSPMASQENCLEKFIPDHSEGVVETDSILEAAVNSILEC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B352-1", "uniprot_id": "A0A8M2B352_DANRE", "id": "A0A8M2B352-1", "name": "", "aln": "----MLPSAGAALLHRPVQRWRGNPVDTALLFHDGVMDDEDDRRLLDFIGDVQALNEYLHGSNSKSIGEDDVTNATFGSASSFFTSDTGGSSEGLKDGHNHLGEFGEAGDAELQLSSSLPFIEDDLDSETSADGVDLGGEDQPFDILQKSLLEADITEQTLAQEALLDS---------QPSLIPTATAFPQQLVSGG--------FAGVAGPGVVAPLAQPQAFIQQ---------VPQLPLPNGP----AGHIQVVGSFNGSASSMMTINSLEQPQILLRQSG----NNSGQGTMFAPSTPN---------------QVSMSFN----KGTIPVQNIIIQR--GPTQQTLVRPIQPKPLQTGGQTVYNISNIGIQPSTTTAGNLVSSAYTATGSPQ-PAQQVKVVN------PASSIVMHSPLGQQAQTQ--SQSNLPQGQFLLPSSISLTPGTTVHGFQAVNGQVLQG------NTQVGDPSSMSTTTYS------------ILTNQNTTVQLIAGQNFSAGGQLIVN---------------------------QGLVSGGQIGQASPTPVVQVSQRPAAAAKVWTSSASPSPTPVQATQTS------SHLTMISSGVQGPQVCQQLSVNPGQHLLMPVGQN-----------------------------ASATSGFQEFQVS-LNQDTTAATQRGQTQLVNLLGTKVLKPLTPAS----------QELPLTPKRPATQQLTRGELVLQQLRQDHSRVLSSDRTPFSSLNDVIDRLLPYHVFQGSPPQDEDFAKVDEEFEAVATQVLSRTQAMVNKYRRLLMVEAERSSPSSEMVMIDRTFNQEERGNLTQDKRMVLVDPDSFLEEFCCGPKRKIPSPEVLTPASHEDK-----------------------------------PSKMETSPSHSISHTGR--------------------------------------DGQSMNSHTETTYRTESQQQEMEEHRRTPIKCILDLKKKTSNSVFGSKSQHAQYPTSPNQSQ-------------------QSSAQGYPSNPGHEQKLSSDPGHVS-------------------LADSDSVLEAAVNSILEC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 295, "similar_positions": 305, "identity": "26.2%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100716-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AFW4-1", "uniprot_id": "A0A8I6AFW4_RAT", "id": "A0A8I6AFW4-1", "name": "ATP-dependent RNA helicase", "aln": "MDSADLPIPGFELRDPPVFASSTAEIKATMKLKETKSKPKSA-SRGTFQRKGIKVVGKWKQVTIDPNLFADGQMDDLVCFEELTDYRLVK---NPSRLFSDE--TTKKRKAQA--VSEEEEEEEGESSSPKKKIKLKKQRDAILVAEGSAAQDECEGKAS-EPGAQGEITVCSDQKVGGATSESLAQTVPRKKKNKGKKKLD--TFQSTAPKVPKKAK-TWMPEVQDQK--ADVSAWRDLFVPKAVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIPMIHSVLQWHKMKAPPIPSSAGVPPR---LGAAAHRGSPCKDGAKSGVLPEEATIETEAQPSDSGVQATAKAGASAASAQAGLFCDDDAGEGPSSLV-EE---KQSKDREEKLDEEQAGKLKQELCDQIAVYKVHPRRPLLGLVLTPTRELAVQVRQHIDAVAK----FTGINTAILVGGMSTQKQQRMLNRHP--EIVIATPGRLWELIKEKHPHLSNLRQLRCLVIDEADRMVEKDHFAELSQLLEMLNDSQYNPNR---------QTLVFSATLTL----VHQAPARILHKKHVKK-MDKTAKLDLLMQKIGMRGKPKVIDLTRNEGTVETLTETKIHCETDEKDLYLYYFLMQYPGRSLVFANSISCIKRLSGLLKVLDIMPLTLHACMHQKQRLRNLEQFAR----------------LEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYIHRSGRTARATSEGLSLMLIGPEDVIN-FKKIYKTLKKD--------------------EDIPLFPVQSKYMDMVKERIRLARQIEKAEYRNFQACLHNSWIEQAAAALEIELEEEMYKGGKADQQEERRRQKQMKILKQELRHLLSQPLFQENLKTRYPTQSGRPPQPVVAPRNVESALSCLSRQKRRR-KKPKEHQ-APPQPSSSTS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ESV0-1", "uniprot_id": "DDX24_MOUSE", "id": "Q9ESV0-1", "name": "ATP-dependent RNA helicase DDX24", "aln": "-----------------------------MKVKETNSKPKLA-SRGTFQRKGIKIVGKWKQVTIDPNLFADGQMDDLVCFEELTDYRLVK---NPSRLFSSE--ETKKRKAQA--VSEEEEEEEGQSSSPKKKIKLKKQRDAARAAEGAAAQNEYEVKAS-EPEAQGEVTACSDQKVGGAKSESLAQAAPRKKKNKGKKKLD--TFQSTSPKLPKKSKKTWMAEVHDQK--ADVSAWRDLFVPKAVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIPMIHSVLQWHKMKAPPIPRSTGMPPREMRFGATAHLGSPCKDRTESGVLPEEARIETEAQPSDSGVQATPETSASAS-AQTLLVCDDDAGEGPSSLE-EKPVPKQNEDGEEKFDAEQAGKLKQELCDQIAIYKVHPRRPLLGLVLTPTRELAIQVRQHIDAVAK----FTGINTAILVGGMSTQKQQRMLNRHP--EIVIATPGRLWELVKEKHPHLSNLRQLRCLVIDEADRMVEKGHFAELSQLLEMLNDSQYNPSR---------QTLVFSATLTL----VHQAPARILHKKHVKK-MDKTDKLDLLMQKVGMRGKPKVIDLTRNEGTVETLTETKIHCETDEKDLYLYYFLMQYPGRSLVFANSISCIKRLSGLLKVLDVMPLTLHACMHQKQRLRNLEQFAR----------------LQDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYIHRSGRTARAASEGLSLMLIGPEDVIN-FKKIYKTLQKD--------------------EDIPLFPVQSKYMDVVKERIRLARQIEKAEYRNFQACLHNSWIEQAAAALEIELEEEMYKGGKADQQEERRRQKQMKMLKQELRHLLSQPLFQENLKTRYPTQSGRPPQPVLASRNIESALSCLSRQKRRR-KKPKEPR-APPQPGSSTS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZR7-1", "uniprot_id": "DDX24_HUMAN", "id": "Q9GZR7-1", "name": "ATP-dependent RNA helicase DDX24", "aln": "-----------------------------MKLKDTKSRPKQS-SCGKFQTKGIKVVGKWKEVKIDPNMFADGQMDDLVCFEELTDYQLVSPAKNPSSLFSKE--APK-RKAQA--VSEEEEEEEGKSSSPKKKIKLKKSK--NVATEGTSTQKEFEVKDP-ELEAQGDDMVCDDPEAGEMTSENLVQTAPKKKKNKGKKGLE--PSQSTAAKVPKKAK-TWIPEVHDQK--ADVSAWKDLFVPRPVLRALSFLGFSAPTPIQALTLAPAIRDKLDILGAAETGSGKTLAFAIPMIHAVLQWQKRNAAPPPSNTEAPPGETRTEAGAETRSPGKAEAESDALPDDTVIESEALPSDIAAEARAKTGGTVS-DQALLFGDDDAGEGPSSLIREKPVPKQNENEEENLDKEQTGNLKQELDDKSATCKAYPKRPLLGLVLTPTRELAVQVKQHIDAVAR----FTGIKTAILVGGMSTQKQQRMLNRRP--EIVVATPGRLWELIKEKHYHLRNLRQLRCLVVDEADRMVEKGHFAELSQLLEMLNDSQYNPKR---------QTLVFSATLTL----VHQAPARILHKKHTKK-MDKTAKLDLLMQKIGMRGKPKVIDLTRNEATVETLTETKIHCETDEKDFYLYYFLMQYPGRSLVFANSISCIKRLSGLLKVLDIMPLTLHACMHQKQRLRNLEQFAR----------------LEDCVLLATDVAARGLDIPKVQHVIHYQVPRTSEIYVHRSGRTARATNEGLSLMLIGPEDVIN-FKKIYKTLKKD--------------------EDIPLFPVQTKYMDVVKERIRLARQIEKSEYRNFQACLHNSWIEQAAAALEIELEEDMYKGGKADQQEERRRQKQMKVLKKELRHLLSQPLFTESQKTKYPTQSGKPPLLVSAPSKSESALSCLSKQKKKKTKKPKEPQPEQPQPSTSAN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RMN7-1", "uniprot_id": "A0A8M1RMN7_DANRE", "id": "A0A8M1RMN7-1", "name": "ATP-dependent RNA helicase", "aln": "-----------------------------MKVKVKKAKVKTPRPRLISSRRGVLVRGQWKAVNVDPSLFSDEGLDGLVCFEELTDYSLVEPEKALTEHVQTERRSQKKRKTNEERRSEDEDAAALEDDSGGKPEKKKKKKNKQKEEEETLEEEQIPAEESPEPTTETPQTNKKKKKRKRKRKKKKKQEEDQEQPEEERSAAAGAEAESAVSAAPQKSR-HWSRASLEAPGPADVSSWRDLLVPEPVLRALAVLGFSAPTAIQALVLPPAIRDRLDILGAAETGSGKTLCFGIPMIHMILQWR--------------------EQTEEHSTPERTHTPAQSLYLQEEHGEDDDDDDDDDEKKDDE----------VIDDDEGGAEGCSAP------PDDPDGQNDPDPASG-----------------VCRPLLGLVLTPTRELAVQVKHHIDAVAQ----FTGIKTAIVVGGMAPQKQHRVLMRRP--EIIIATPGRLWEMIREKHPHLQDLRQLRCLVLDEADRMVEKGHFAELESLLELLNTSQFSSRR---------QTFVFSATLTL----VHSLPSRLQQKKKKQRPAEQRSKLQLLMEKVGVRDKPKVIDLTRKQATVETLTETRISCTKEDKDLFLYYFLLQFPGRSMVFANSIACIKRLYALLHLLDCTPLMLHANMHQKQRLKNLERFAE----------------NTRCVLLTTDVAARGLDIPDVQHVIHYQVPRTSETYVHRSGRTARATREGLSLLLISPDDLLN-YRRICRTLDKS--------------------EELPVFPVESKCMAAVKERVDLAHRIEKMEYFHSRQTQHNSWVRQAAEAMDIDVDDELLMGSSKGEDEEREQQREKQMLRKQLKILISQPVFRSQMKTRYPTQMGKLLLPTLP---QDTALASLKQDTQSSTRRR----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38112-1", "uniprot_id": "MAK5_YEAST", "id": "P38112-1", "name": "ATP-dependent RNA helicase MAK5", "aln": "-----------------------------MGKKRAPQKGKTVTKPQEIIVDESKLN--WKPVDIPDTLDDFG---GFYGLEEIDGVDVKVVDGKVTFVTKKD--SKVLKDSNKEKVGDDQESVENESGSDSES-ELLEFKNLDDIKEGELSAASYSSSDE---DEQGNIESSKLTDPSEDVDEDVDEDVLKENVFNKDINID----DISPVNLPEWTN--------------------LAPLSMTILQSLQNLNFLRPTEIQKKSIP-VIMQGVDVMGKASTGSGKTLAYGIPIVEKLISNFSQ---------------------------------------------------------------------------------------------------------------------------KNKKPISLIFTPTRELAHQVTDHLKKICEPVLAKSQYSILSLTGGLSIQKQQRLLKYDNSGQIVIATPGRFLELLEKDNTLIKRFSKVNTLILDEADRLLQDGHFDEFEKIIKHLLVERRKNRENSEGSSKIWQTLIFSATFSIDLFDKLSSSRQVKDRRFKNNEDELNAVIQHLMSKIHFNSKPVIIDTNPESKVSSQIKESLIECPPLERDLYCYYFLTMFPGTTLIFCNAIDSVKKLTVYLNNLGIPAFQIHSSMTQKNRLKSLERFKQQSAKQKTINHSNPDSVQLSTVLIASDVAARGLDIPGVQHVIHYHLPRSTDIYIHRSGRTARAGSEGVSAMICSPQESMGPLRKLRKTLATKNSVSTDLNSRSTNRKPIKWQNTVPLLPIETDILSQLRERSRLAGELADHEIASNSLRKDDNWLKKAADELGIDVDSDEDDISKSNSDTFLLKNKNKKMQKTINKDKVKAMRATLNELLSVPIRKDRRQKYLTGGLVNLADNLVKKRGHNSIIGHEKTNALETLKKKKKRNN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : * : ** * : .: .: :**: . : : . : :.:: .:::: :..* : : : : * . . : . . .:. : ::: : : : *: :. :. .:*::* *.* ** ** :. .* : :*::* *.*******.:.**::. ::. : :.*::******* ** .*:. :.. : . :.**:: ***:*:* :*::*****: *::.:.: : : ::. *::*****:::..** *:..::: * .: . . **::****::: . . :: .:: :. : :: **.*: ...** :** . :. . . :.*: * * ::*:: **** :** :::*.*:* .:*:* *: *. .: :*: * **:**:.**:* . **:::********** *******::**::: *:********* **:* :: .*:: :. ::: :** .. : :*::*:::. : ::** ** .: . * .:.*:.:** : *:::.: .. ..: :::: :: : : :. . * : .: : .: . : ", "identical_positions": 155, "similar_positions": 251, "identity": "16.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100716-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62975-1", "uniprot_id": "ZPI_RAT", "id": "Q62975-1", "name": "Protein Z-dependent protease inhibitor", "aln": "MRVVSSLFLPVLLAEVWLVSSFNLSSHSPEAPIRLVSQDYENQTWEEYEWADPRD--------------------------DNEYWLRAS-QQLSNETSSFGFSLLRKIS-------------MRHDGNVIFSPFGLSVAMVNLMLGAKGETKVQVENGLNLQALS---QAGPLILPALFKRVKETFSSNK---------------------KLGLTQGSFAFIH-KDFEIKKTYFNLSTMYFDTEYVPTNFR-NSSQARGLMNHYINKETEGKIPKLFDEIN--PETKLILVDYILFKGKWLTPFDPIFTEADTFH---LDKYKAVKVPMMYREGNFASTFD-KKFRCHILKLPYQG--NATMLVVLMEKS--GDHLALEDYLTTDLVEMWLQDMKTRK----MEVFFPKFKLNQRYEMHELLKQVGIRRIFSTSADLSELSAVARN----------------------------LQVSKVVQQSVLEVDERGTEVVSGTVSEITAYC--------MPPVIKVDRPFHFIIYEEMSQMLLFLGRVVNPTVL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R121-1", "uniprot_id": "ZPI_MOUSE", "id": "Q8R121-1", "name": "Protein Z-dependent protease inhibitor", "aln": "MRVASSLFLPVLLTEVWLVTSFNLSSHSPEASVHLESQDYENQTWEEYTRTDPREEEEEEEEKEE--------------GKDEEYWLRAS-QQLSNETSSFGFNLLRKIS-------------MRHDGNVIFSPFGLSVAMVNLMLGTKGETKVQIENGLNLQALS---QAGPLILPALFKKVKETFSSNR---------------------DLGLSQGSFAFIH-KDFDIKETYFNLSKKYFDIEYVSINFQ-NSSQARGLINHCIVKETEGKIPKLFDEIN--PETKLILVDYVLFKGKWLTPFDPSFTEADTFH---LDKYRAIKVPMMYREGNFTSTFD-KKFRCHILKLPYQG--NATMLVVLMEKT--GDYLALEDYLTVDLVETWLQNMKTRK----MEVFFPKFKLNQRYEMHELLKQMGIRRLFSTSADLSELSAMARN----------------------------LQVSRVLQQSVLEVDERGTEAVSGTLSEIIAYS--------MPPAIKVNRPFHFIIYEEMSRMLLFLGRVVNPTVL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UK55-1", "uniprot_id": "ZPI_HUMAN", "id": "Q9UK55-1", "name": "Protein Z-dependent protease inhibitor", "aln": "MKVVPSLLLSVLLAQVWLVPGLAPSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKASE-------------------EEKAWLMASRQQLAKETSNFGFSLLRKIS-------------MRHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQALK---PTKPGLLPSLFKGLRETLSRNL---------------------ELGLTQGSFAFIH-KDFDVKETFFNLSKRYFDTECVPMNFR-NASQAKRLMNHYINKETRGKIPKLFDEIN--PETKLILVDYILFKGKWLTPFDPVFTEVDTFH---LDKYKTIKVPMMYGAGKFASTFD-KNFRCHVLKLPYQG--NATMLVVLMEKM--GDHLALEDYLTTDLVETWLRNMKTRN----MEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRN----------------------------LQVSRVLQRTVIEVDERGTEAVAGILSEITAYS--------MPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPTLL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AK66-1", "uniprot_id": "A0A8M3AK66_DANRE", "id": "A0A8M3AK66-1", "name": "", "aln": "MEFR---LLLVFISACFLCSAEHEELRTPDIS------------------------------------------------------------DLAFRNTDFAINLYRKIS-------------SLHDRNVVFSPLSVSTCFSALLLAAQGSTRTEILKGLNLEALD---GGDSRRVPELFQQLHQNIS-------------------------LQMEQGTALFLD-QHFHLQTNFSQQIQRFFNAEVLRVDFS-KPAVCRSLINEFVSRKTGRKVLEMLESVE--PLTQMMLLNTIFYKGDWERPFNPNNTEKSRFY---VDKYNIVQVPMMMLEEKFSVVED-RDLRARVLRLPYRG--GASMLILLPNAD--ADYTAIEDEISAERLHGWIKNMRRMK----MEVHLPRFRMDQSYHMHELLPQLGISSVFQDSADLTGLSRDAH-----------------------------LKVSQVLHKAVIEVYEQGTSAASSTSVGITAYS--------LPDTFIINRPFFFFLYHEETASLLFMGRVIDPTLS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VL44-1", "uniprot_id": "Q9VL44_DROME", "id": "Q9VL44-1", "name": "", "aln": "-----------------MSEAANPTP----------------------------------------------------------------------YDCHIGAGIYHSIAT------------SFAEQNVVVSPLLLEATLSLLFLGSDGATAEELQKQLRLKQRF---ASN-AKMANFYAAELGNITTDA---------------------DTFLQLQNRLMLS-SESGVADDFQKIAQTYFHATAECVDLE-QTEKLRRHISEQILASVGGGSWKDIHVAGGSSANTLLLLLAANLQSKWFLPFSAYRTGLYEFH---SGS-QVKSVPMLFDDDMFVKFAELRDLDARAIELPYEHAEELSMLLILPNQR--GGLQELEKQLHDLDLGALQQRMQMEG----VQVLLPKFSIDFECSLRQPLKQLGFEEIFAASANFKHLHASAN-----------------------------LPIADVLQKLRINLNESGSGSGPELPKNATEYKPIVISNSSRQKFFRADHPFFFAIRSEN--VTYLMGHVVEF----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLU4-1", "uniprot_id": "SP28D_DROME", "id": "Q9VLU4-1", "name": "Serine protease inhibitor 28Dc", "aln": "-MWRLLLALLLVSSVCCESELFRDDLRTPETMAYINGLMQRRHQMQQEAQQHIQAIPPAVPLQSPGLVNGLGNQNDPALNRISGTSVKPSNLPAAYSNGYVDLATSDRIANSVLNFANILGQHLANGKTQIYSPLSIVHSLALLLLGAKGRSYEELSTVFDIPDTSRLHEQFGLMLQDLQQPTREAISAGRPLTDWRASSAMRSNRRAQRPGAHEVHLANGLFTQ-TGYTLNPDYRRVIVEVYASDLQIQDFEGSPATARYNINAYVAQHTKNHIENIIASDIP-QTTRMILANALYFKAFWETDFIESATRPDNFYPNGEGTEPVMRVQMMATGGAYPYHED-HELGCKIIGLPYRG-NLSTMYIIQPFKSSVRELMALQKRLTADKIESMISRMYRRA----ALVAFPKMHLTESVNLKTVMQRMGLGGIFSAVQNDLSLIATNEATRTNALGGNSLQNLEAQRRAGTGGARSDLVVDDIVHKVDFTVNEQGTEAAASSVTYLKKSG--------PDVLFRGDTPFMVLVRHDPTKLVLFYGLINEPPAAA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWB4-1", "uniprot_id": "Q9VWB4_DROME", "id": "Q9VWB4-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------MKLGFLGLFGMVLMIMFYEGAEGYTVNELRDVLGIYVDYPTLRRWYEDVRAYHYLNSENTKLFSLR------------------YAYYDDVGDLELVKGYNSVVLEGVGEGNVVLREGRPRGVDFD---QGASIIINDDIDKASHAKIFSSYSRRSFNSTVTVLGITVSYFKAKWKYPFDKSQTKVEQFYN--DGGSPAGKVEMMVQTGKYAYVNNVKGLQADVLELPFGEH-ELVMIVLLPKSS--QGVNLVLYQLKNLGLHRLLEKLEASKNETDVEVKLPKFDTRSVLSLEDTVYDAGLTDLRNDFADLDKLLIAIGHRG--------------------------ACLTLYHQFARIVVDEEGLPN--AVPQKSSGKN---------NIKFHVNRPFAYLVLQKKHKLLIHSGVFREGEIQ-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : .: * : :: : : : . : : . :: :. : . :: :. * * * *: . * *: : : : : . : **: * :: : : : : * :*:: :. : *: : : * : : : : * * : : ** : . * . : ", "identical_positions": 19, "similar_positions": 61, "identity": "3.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100716-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUT0-1", "uniprot_id": "D3ZUT0_RAT", "id": "D3ZUT0-1", "name": "", "aln": "MALPGSPEPPRGAPRKVPSLLEMGSLCLDSDIILGFTSHLLRRRGKVAECRSARESPP-LEVSPRKRLPAGLDQDLCSSRPAPEGAGAS--AEQGHSTGGGGWCRHCHTKLVELKRQAWKLVSGPGTPLRDPCLSTLLLDKLPASGVQPSCRPDTESRCDVCTTHLHQLTREALRLLQTPASHEDPDASRGG--LGAP-----------SPRDPPGPVGLMGRQP-PVGPDRRKAAAWPSG---------PSVQVSVAPAGLGGALSTVTIQAQQCLEGVWSLSRVNSFLPPTCLAEAAVAAVAVADTVRDCPPTAGSDRMSKAWGRGTACTTALVTPAPGTSAGGSTAPSAAASFFIRAAQKLSLASKRKKHPPPPAPSARGSSTYATDFSGTLQLWPPPVPPCLLRAASKAKENPSNFGKVKVMLRIWPAQGVQRSAESTSFLKVDSRKKQVTLYDP-AAGPPGCAGLRHAPTAPVPKMFAFDAIFPQDSEQAEVCSGTVADVLQSVVGGADGCIFSFGHMSLGKSYTMIGKDSSPQ------------SLGIVPCAISWLFRLIDERKERLGTRFSIRVSAVEVCGHDQSLRDLLAEVASGCLQDTQSPGVYLREDPVCGTQLRNQNELRAPTAEKAAFYLDAALAARS-----TSRAGCGEDARRTSHMLFTLHVYQYRVEKCGQGGMSGGRSRLHLIDLGSCEAAPSRGGEASGGPLCLSLSALGSVILALVNGAKHVPYRDHTLTMLLRESLATTSCCTTMIAHISDSPTHHAETLSTVQLAARIHRLRRKKGKHASSSSGGESSCEEGRARRPPHLRPFHPRTVVLDPDRSAPALSGDPDYSSSSEQSCDTVIYVGPGGTALSDRELTDNEGPPDFVPIIPALSRR-RPSEGPRDADHFRCSTFAELQERLECIDGSEGF----------PGP----------QGGSDGAQASPSRGSRKPSLPESTCLRKAVAPS-VVTGCPRSSSGQETPRSTSEP------------SKTGPQGD--QRVDG-TRPEPPAPDKITGGGG-----------RRLLPSPAPPPPRQPEARGVPTEPGGEGADSGPRTPPVGMSGQAPLPALLSDSAY-------------PSARGRHLDRGLLTTTVTLQQPVELNGEDELVFTLVEELPLGGLAGATRPSSLASMSSDCSLQALASGSRPVSIISSINDEFDAYTSQVSEGPGDAGE---LPEGTVWPGGSPASSIGSWLSDVGVCLPESRGTTPQPPFNPD-SAAGPGP------------PEFLTPGSSLEDSKVRSSECGRP---DNPGSSARSPHPGEAVSITQT-----QPGREPWARSPHEAASAQTIHSSLPRKPRTTSTVSR---ARPSRGP------YSPGGLFEDPWLLRAEDCDTRHIASTG----------------RAPSPTPGSPRLPETQIVLACAQRVVDGCEVASRMSRRPEAVARIPPLRRGATTLGVTTPTASCGDAP--AEATAHSGSLKATSSSKKSVSPK-GAFFPRPSGAGPPAPPVRKSSLEQ-------STALTPTQALGLTRTGATSAFRGEEEARPTGRS----------DSSVPKATSSLKARAGKMEVPHRPSGHMSLERCEGLTHGSSK--------VRDVAGRPPRAVPRLG--VPPASPPLGPGPACR-------SSPAKG-IGATKPPAGGAKSRNLGPSTSRALGAPVKP-LAPVVGKT---TGGAVPGPRTAPRSVPGIGA----KAGRGTIMGTKQAFRAAHSRVHELAASGSPGRGGLTWGSTDSDSGNDSGVNLAEERQPSSPALPSPYSKVTAPRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFYHSGGSSGYESMIRDSEATGSASSAPDSMSESGAASPGARSRSLKSPKKRATGLQRRRLIPAPLPDAAALGRKPSLPGQWVDLPPPLAGSLKEPFEIKVYEIDDVERLQRHRLPLRENEAKPSQDVEKGPVCISSKLRLAERRQQRLQEVQAKRDHLCEELAETQGRLMVEPGRWLEQFEVDPELEPESAEYLVALEQATAALEQCVNLCKAHVMMVTCFDIGVAATAAVPGPQEVDV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q52KG5-1", "uniprot_id": "KI26A_MOUSE", "id": "Q52KG5-1", "name": "Kinesin-like protein KIF26A", "aln": "--------------------------------MVGRGASLCAVQPAVAECGPARETPP-LEVSPRKRLPAGLDQDPCSSRPAPEGAGAS--AEQSHSAGGGGWCRHCHTKLVELKRQAWKLVSGPGTPLRDPCLSTLLLDKLPASGVQPACRPDTESRCDVCTTHLHQLTREALRLLQTPASHEDPNASRGG--LAAP-----------SSRDPPGPVGLMGRQP-PVGPDRRKATAWPPG---------PSVQVSVAPAGLGGALSTVTIQAQQCLEGVWSLSRVNSFLPPTCLAEAAVAAVAVADTVRDCAPAAGPERMSKAWGRGAACTTALVTPAPGTSAGGSTGPSAAASFFIRAAQKLSLASKRKKHHPPPAPSTRGTSTYPTDFSGSLQLWPPPVPPCLLRAASKAKENPSSFGKVKVMLRIWPAQGVQRSAESTSFLKVDSRKKQVTLYDP-AAGPPGCAGLRHAPTAPVPKMFAFDAIFPQDSEQAEVCSGTVADVLQSVVSGADGCIFSFGHMSLGKSYTMIGKDSSPQ------------SLGIVPCAISWLFRLIDERKERLGTRFSIRVSAVEVCGHDQSLRDLLAEVASGSLQDTQSPGVYLREDPVCGTQLQNQNELRAPTAEKAAFYLDAALAARS-----TSRAGCGEEARRSSHMLFTLHVYQYRVEKCGQGGMSGGRSRLHLIDLGSCDAAVGRGGEASGGPLCLSLSALGSVILALVNGAKHVPYRDHRLTMLLRESLATTNCRTTMIAHISDSPAHHAETLSTVQLAARIHRLRRKKGKHASSSSGGESSCEEGRARRPPHLRPFHPRAVVLDPDRSAPGLSGDPDYSSSSEQSCDTVIYVGPGGMALSDRELTDNEGPPDFVPIIPALSRR-RPSEGPRDADHFRCSTFAELQERLECIDGSEAF----------PGP----------QGGSDGAQASPARGGRKPSLPEATPSRKAVAPT-VVTSCPRGSPGHDTHRSASDP------------SKTGTQSE--QRVDG-SRPEPPASDKTSGGGG-----------RRPLPSPAPPPPRQPEAQGIPKEPGGEGTDSVLRTPPVGMSGQAALPPLLSDSAYL-----------SPSARGRHLERGLLTTTVTLQQPVELNGEDELVFTVVEELPLGGLAGATRPSSLASMSSDCSLQALASGSRPVSIISSINDEFDAYTSQMSEGPGDPGE---FPEGTAWAGGSPASSIGSWLSDVGVCLSESRGPTPQPPFSPN-SAAGPGP------------PEFPTPGSSLEESKVRSSECGRP---DNPGS-ARSLHPGEAVATTQT-----QPGREPWARSPHEVASAQTIHSSLPRKPRTTSTASR---ARPSRGP------YSPGGLFEDPWLLRAEDCDTRQIASTG----------------RAPSPTPGSPRLPETQMMLACAQRVVDGCEVASRMSRRPEAVARIPPLRRGATTLGVTTPAASCGDAP--AEAVVHSGSLKTTSGSKKSVSPK-GAFFPRPSGAGPPAPPVRKSSLEQ-------STALTPTQALGLTRAGAPSAFRGEEEARPSGRS----------DSSVPKATSSLKARAGKMDVPYRPSGHMSLERCEGLAHGSSK--------VRDVVGRPPRAVPRLG--VPSASPPLGPAPACR-------NSPAKG-VGATKPPAGGAKGRNLGPSTSRALGAPVKP-LGPVAGKT---AGGAVPGPRAAPRAVPGIGA----KAGRGTIMGTKQAFRAAHSRVHELAASGSPSRGGLSWGSTDSDSGNDSGVNLAEERQPSSPALPSPYSKVTAPRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFYHSGGSSGYESMIRDSEATGSASSAPDSMSESGTASLGARSRSLKSPKKRATGLQRRRLIPAPLPDAAALGRKPSLPGQWVDLPPPLAGSLKEPFEIKVYEIDDVERLQRHRLPLRENEAKPSQDAEKGPVCISSKLRLAERRQQRLQEVQAKRDHLCEELAETQGRLMVEPGRWLEQFEVDPELEPESAEYLVALEQATAALEQCVNLCKAHVMMVTCFDIGVAATTAVPGPQEVDV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULI4-1", "uniprot_id": "KI26A_HUMAN", "id": "Q9ULI4-1", "name": "Kinesin-like protein KIF26A", "aln": "--------------------------------MVGRGVPLCAAQPAVAEGGPAREPPPLLEVSPRKRLPAGPDQDPCGSRPAPEGAGAG--PEQGHSAGGGGWCRHCHTKLVELKRQAWKLVSGPGTTLRDPCLSALLLDKLPAPGALPACRPEAERRCDVCATHLQQLTREAMHLLQAPASHEDLDAPHGGPSLAPPS-------TTTSSRDTPGPAGPAGRQPGRAGPDRTKGLAWSPG---------PSVQVSVAPAGLGGALSTVTIQAQQCLEGMWSVSRVNSFLPPACLAEAAVAAVAVADTVRECPPVAGPDGLSKAWGRGGVCTSALVTPTPG-SVGGSTGPSAAASFFIRAMQKLSLASKRKKPHPPPPPATRGTSTYPTDFSGVLQLWPPPAPPCLLRAASKTKDNPGSIGKVKVMLRIWPAQGAQRSAEAMSFLKVDPRKKQVILYDP-AAGPPGSAGPRRAATAAVPKMFAFDAVFPQDSEQAEVCSGTVADVLQSVVSGADGCIFSFGHMSLGKSYTMIGKDSSPQ------------SLGIVPCAISWLFRLIEERRERTGTRFSVRVSAVEVCGRDQSLRDLLAEVAPGSLQDTQSPGVYLREDPVCGAQLQNQSELRAPTAEKAAFYLDAALAARS-----TSRAGCGEDARRSSHMLFTLHVYQYRMEKCGRGGMSGGRSRLHLIDLGSCEAAAGRAGEAAGGPLCLSLSALGSVILALVNGAKHVPYRDHRLTMLLRESLATAGCRTTMIAHVSDAPAQHAETLSTVQLAARIHRLRRKKAKYASSSSGGESSCEEGRARRPPHLRPFHPRTVALDPDRTPPCLPGDPDYSSSSEQSCDTVIYVGPGGAALSDRELTDNEGPPDFVPIIPALSRH-RPSKGPRDADHFRCSTFAELQERLECMDGNEGP----------SGG----------PGGTDGAQASPARGGRKPSPPEAASPRKAVGTP-MAASTPRGSSGPDTHQGTPEP------------CKAIVWGD--QREDSSAWPELLVPEKAAVSGG-----------RRPLPSPAPPPPQLLEACRAPEEPGGGGTDGVARTPPVGMSGQVAGSPMLPGATCP-----------RLAAGSRCPERGLLTTTVTLQRPVELNGEDELVFTVVEELSLGALAGAGRPTSLASFDSDCSLRALASGSRPVSIISSINDEFDAYTSQAPEGGP--------LEGAAWAGSSHGSSISSWLSEVSVCTADSRDPTPQPRFSPD-SLAGLDP------------GGPPALDGSLGDGSSGFLGPDRP---DSPGP-TWGPCPGEVAAVAPS-----RPGREPQAGPSRWASAAQTIHSSLPRKPRTASATTRVGCARLGQSP------PGRGGLFEDPWLLRVGECDT-QAASAG----------------RAPSPTLGSPRLPEAQVMLACAQRVVDGCEVAARAARRPEAVARIPPLRRGATTLGVTTPAVSWGDAP--TEVVACSGSLKASPTSKKGLAPK-AGFLPRPSGAAPPAPPTRKSSLEQRS-----SPASAPPHAVNPARVGAAAVLRGEEEPRPSSRA----------DHSVPRATSSLKARASKVEAAHRLAGHASLERYEGLAHSSSK--------GREAPGRPPRAVPKLG--VPPSSPTHGPAPACR-------SGAAKA-VGAPKPPVGGGKGRGLVAGGSRALGPSVKLSTASVTGRS---PGGPVAGPRAAPRAGPSVGA----KAGRGTVMGTKQALRAAHSRVHELSASGAPGRGGSSWGSADSDSGHDSGVNVGEERPPTGPALPSPYSKVTAPRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFHHSGGSSGYESLRRDSEATGSASSAPDSMSESGAASPGARTRSLKSPKKRATGLQRRRLIPAPLPDTTALGRKPSLPGQWVDLPPPLAGSLKEPFEIKVYEIDDVERLQRPRPTPREAPT-------QGLACVSTRLRLAERRQQRLREVQAKHKHLCEELAETQGRLMLEPGRWLEQFEVDPELEPESAEYLAALERATAALEQCVNLCKAHVMMVTCFDISVAASAAIPGPQEVDV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B5X7-1", "uniprot_id": "A0A8M2B5X7_DANRE", "id": "A0A8M2B5X7-1", "name": "", "aln": "-MDLPNSNGSSGADKQKPGLIDLGTFFVDADIIFGFTSHLLKRKAKVEGCSSGESSLS-FELSPRKRLSAE--EERCASRPPPEGAGAVSVSESDRDDAKPDLCKQCQMTVAELRRQALTLSDP--ASLKDPGFASFIIEQLQIPDWLLKGG-HEGTRCPACGSSAQQLKQQALQTLQDLYPCPDMPSLPSSTFPGHPARLMTHGVVTVSSRPTKSRIPHPAHSVLPVGE-RQRELGWSQSSSSSVSTLKPSVQVTMAGRPLAGTISSVTIQAQQYLEGMWSISRVNNFLPQPNPALGLVGQAEQSE-------LSSDNTISRVNPSKQRCPVQFGQTAPSSSEHPS---SAAASFFIRAAQKLNLSSKRKKQQPP-LVYPQEPSIYPTNFSAVLQFSPPPAPPCLLRAGSKAKENPG-MGKVKVMMRICPSLGVVDSSESMSFLKVDMRKKQLTLYDP-SLHTQPTS-VHRRAVLPAPKMFAFDAVFSQDASQAEVCSGTVAEVIQSVVNGADGCIFCFGHVKVGKTYTMIGTDSSMQ------------SLGIAPCAISWLFKLINERKEKTGTRFSVRVSAVEIYGKDESLQDLLSDVPTGSLQDGQSPGVYLREDPICGTQLQNQCELRAPTAEKAALFLDAAIAARS-----TNHPDADEEDRRNSHMLFTLHIYQYRMEKSGKGGMSGGRSRLHLIDLGSCEKVLCKSRDAGGG-LCLSLTALGNVILALANGAKHVPYRDSKLTMLLRDSLGNINCRTTMIAHISDSPANYAESLTTIQLASRIHRMRKKKSKYASSSSGGESSCDEGRIRRPPHLRPFHPRTVALDPD--LPSFLSDPDYSSSSEQSCDTVIYVGPGGAAISDRELSDNEGPPAFVPIIPSLNRKQRGKDGPVDRDHFKCNTFAELQERLECIDGSEEPTAFVVESGENSGSSKMDHSANKLKEGSSCISVSPKTPTKVLSSTQDSISKKSISVTSKLPSSPKHKSKLEHSKLQSAASDKDLRDMCENVCRTSADGEKVQMSESGSLCTTGKQSKTIISQNSEPVVREKVFFNKKLPKPAPPPPQQRDYVTVGSETE---EKSATRVPPIGMSHQKRGDSIGNSAVKVHHLNPRTPGEMRSNLRERCMEKDILRTTVTLKQPVELNGEDELVFTLVEELSIGSIVDSGRPSSIVSFNSDCSLQALASGSRPVSIISSINDEFDAYTCSVGNSEANVKIGAPLQEKTFASLGSRGSSITSWLSEVSVCTLESDGAQSADVFLPQGTNTGPDSNFYFDSLNMFQSSTQKEPKNSLNDSGCSFSDLESDSAISSKLSLNKCPSSPEAPQLTVKNFPKLEKANTIHISDTQSFQDSQAVQFGLSRKIKPTSSIAQSSSISGSSSSSNWRREPLRQDCIPDPWHRGESLMDTSIISNSGSSSRLVKNGMSGIPARKAGTSSNSIPRIPKT-LGPNSSQRVVDGCEKSCNS-RKIEPPSKMPQLRRGATTLGTVPVIHSSIDVKLAQEIVSSMGSLKFSSLGKSGKANKQEETMSKPGNVSPPLPPVRKSSLDQKNRILFPSSALKSAYDAGKSLAPRAAGLELDIEVSSRGDSNSLRASNLKLEHSLMKTTSSLKARGARGDTGQLHGSQISLERCDSLSSLGSKPALSRENSGASLNSKSSKSISRFGSPVATSSPTTTSSPSCVNQVASLKSGMVKGSLNARSVPVNANKARTLSASNSKALSSSTKSLAAPTTRNANLPPSGKTALPRAAAAASSVAAAGGTGKSTRGTIMGTKQAMRAANSRVSELALANPSTK--QTRGSGDSDSGNDSGVALNEDKHTPIPILPSPYSKITAPRRPQRYSSGHGSDNSSVLSGELPPAMGRTALFYHSGGSSGYESMIRDSEATGSASSAHDSMSESGMSSS-GRTRSSKVPKKRSNGLQRRRLIPAPLPDTSSLG-KTGTTGQWVDLPP-MSGPLKEPFEIKVYEIDDVERLQRRRQEKT----------DEGLMYFSTKMKVLEKRQQQIRDLRAKHKTLKEELDDTKSRLMMDPSKWTGEFEVDQDLDQESQEYLEALEQATADLEYCVNLCKSRVMMVTCFDIRVSSDVQE-GPREVEV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLW2-1", "uniprot_id": "KI26L_DROME", "id": "Q9VLW2-1", "name": "Kinesin-like protein CG14535", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATTSTSNMSRNGGFCGALQRAPPPMPPTLIRRLSSRE--CYGVGKVKVMLRVADRD-RNSGGTEPDFMALDKKKRQVTLTDPRTACPPPQAAQERAPMVAAPKMFAFDNLFTGEDKQSDVCASALSEVIPAVLEGSDGCLLAMGYPATGQAQTVLGELGGGSGSGSASGSGVACSLGAAPCAIAWLYKGIQERRQKSGARFSVRVSAVGVSATKPDALSQDLLISHAAESD-DSPGIYLRDDFLGG-----PTELRAPTAERAALFLDSALAGRLKSSGSTASGSSGCAAPLESALIFTLHVYQYSLSR--KGGVAGGRSRLHIIDLGGCANRNGG----------LPLSGIGNILLAILSGQRHPPHKDHPLTPLLKDCLAPITCHVAIVAHVR-PEQSYQDALSTIQIASRIHRLRRRKHRVPMPLAVGLAQGLGGNGSS-----------------------AGSGADPSSSEISADTVIYMGP------NDDATDGEHPPVYLPSLTAGDNR----------GVMSKALKGSGLEKPPSKSASNSP--------------------------MMMKKAMAAEKAKKLPGSHTGSLKRQAGAG--ACSSPMIPHEQPQIQAMGSP--------------------------------IPIPRHMVSKGS-------------MVPSPKGSPMRRAHPG------------AALEQLEAGMRKITEEQWID----------------------GPRVSRAKVAEARHLMREVNHVKQCETWVDGPKSQSCRSLTACNLPAAGGSQTQGYGFMDAHKKTMIRQWVENQTTQVFQSTVSAS------------------------NSPTALHWKLSQLKQKSLDLPDRPAFNPE-------------------------PSLDLNQPCFESLPLLDP---------------------------------APPDGDEDEDSGPSEVPPALP--------------------------------LLDDPLGSRDISQDNLHRMLSR---------------------HVSREQLHEAELVASRASSSHHPSQRSIDCGLQVTEEEIARTMSRDRDHDPSAHPLSALSHCDN----ISFVSSFNMACESFSECGERARQQFDQLARLH----------------------EIFTSQLAMAEVTPSAALFRTDIG-------------------------SVFSEPVYHFNVGQ---SSVCSEPAYRLTPSPPK--------------------------QPSHSPSQGSLPSLN-------------------------GIMEIAGMDDYALLRQPDGASDPNLQKG-------------------------------------EKRFTPQHDDICELDEKS------MAAAVGKGNSLEDAQHKLNEITNILPLAAQSRLPLLPLNTSSEAYDSGHDSNST-------PRTSKHSGISRRAESGYHSVATVRDSDESSFASGMSKGQRHRITVSGTGAVTSAGIGNYQRQCHKKR--------------HRQDQAGNNKGLCNWLLTPFSCTYPETEGEISDF-------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .*.. ** *** ** *:* *. : .******:*: .. .*: :* :*:*: * ** : . : .: . ..******* :*. : .*::**:.::::*: :*: *:***::.:*: *:: *::* .. . *** .****:**:: *:**::: *:***:***** : . . . . :. .. .* :***:***:* : * ********:**::**:*:*.* * ... * ::****:*** :.: :**::*******:****.* *.*:.:*.::**: .* :* *::* ** **::.*. * .:::**: . : ::*:*:*:*:****:*::* : . . : * :. *. .. .**** *.*****:** : : :*.* ** ::* :.: ..: . : .. *: . ...: .. . : . .. :: . . * : . : . :*.* .* : . . . ** : .: : : * : *: : * . :. . .:. . *:: * .. .: . : . :.. . :. * . .* : .:. .* . * *: .* : .. : .*. : ** *. : . :: :: : :. . .: : : : *. . : . .*:: : . . . : : : . .. . .: :. : * :. : :. . . * *: .* .. **. . *: : . ** . . . :: : . :. : ** . : . ..:* .*: : * * . :. .: *.***.*:.: * : ::.: :: .. : ***: :. **. .. . * . * : : ::* : . .*: .* : .:. .: . **.*. ", "identical_positions": 218, "similar_positions": 354, "identity": "10.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100721-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LF67-1", "uniprot_id": "A0ABK0LF67_RAT", "id": "A0ABK0LF67-1", "name": "", "aln": "---------------MEAPPWEPVRNDSLPPTLSPAVPPYVKLGLTAVYTAFYALLFVFIYAQLWLVLRYRHKRLSYQSVFLFLCLFWASLRTVLFSFYFRDFVAANSFSPFVFWLLYCFPVCLQFFTLTLMNLYFTQVIFKAKSKYSPELLKYRLPLYLASLFISLVFLLVNLTCAVLVKTGDWDRKVIVSVRVAINDTLFVLCAISLSICLYKISKMSLANIYLESKGSSVCQVTAIGVTVILLYTSRACYNLFILSFSQIKNVHSFDYDWYNVSDQVSRTQQGAAQGPDQWNVESCFNTGDQADLKSQLGDAGYIVFGVVLFVWELLPTTLVVYFFRVRNPTKDLTNPGMVPSHGFSPRSYFFDNPRRYDSDDDLAWNIAPQGLQGSFAPDYYDWGQQNNSFLAQAGTLQQDSTLDPDKASQG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BNQ3-1", "uniprot_id": "G137B_MOUSE", "id": "Q8BNQ3-1", "name": "Integral membrane protein GPR137B", "aln": "---------------MEAPPWEPVRNDSLPPTLSPAVPPYVKLGLTAVYTVFYALLFVFIYAQLWLVLRYRHKRLSYQSVFLFLCLFWASLRTVLFSFYFRDFVAANSFSPFVFWLLYCFPVCLQFFTLTLMNLYFTQVIFKAKSKYSPELLKYRLPLYLASLFISLVFLLVNLTCAVLVKTGDWDRKVIVSVRVAINDTLFVLCAISLSICLYKISKMSLANIYLESKGSSVCQVTAIGVTVILLYTSRACYNLFILSFSQIKNVHSFDYDWYNVS--------------------------DQADLKSQLGDAGYVVFGVVLFVWELLPTTLVVYFFRVRNPTKDLTNPGMVPSHGFSPRSYFFDNPRRYDSDDDLAWNIAPQGLQGSFAPDYCDWGQQNNSFLAQAGTLHQDSTLDPDKASQG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60478-1", "uniprot_id": "G137B_HUMAN", "id": "O60478-1", "name": "Integral membrane protein GPR137B", "aln": "MRPERPRPRGSAPGPMETPPWDPARNDSLPPTLTPAVPPYVKLGLTVVYTVFYALLFVFIYVQLWLVLRYRHKRLSYQSVFLFLCLFWASLRTVLFSFYFKDFVAANSLSPFVFWLLYCFPVCLQFFTLTLMNLYFTQVIFKAKSKYSPELLKYRLPLYLASLFISLVFLLVNLTCAVLVKTGNWERKVIVSVRVAINDTLFVLCAVSLSICLYKISKMSLANIYLESKGSSVCQVTAIGVTVILLYTSRACYNLFILSFSQNKSVHSFDYDWYNVS--------------------------DQADLKNQLGDAGYVLFGVVLFVWELLPTTLVVYFFRVRNPTKDLTNPGMVPSHGFSPRSYFFDNPRRYDSDDDLAWNIAPQGLQGGFAPDYYDWGQQTNSFLAQAGTL-QDSTLDPDKPSLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F594-1", "uniprot_id": "G137B_DANRE", "id": "E7F594-1", "name": "G protein-coupled receptor 137Ba", "aln": "-----------------------MQKDSLP-TLSPAVPPYVMLGLTVAYTIFYCLLFVFVYVQLWLVLRYRHKRFSYQTVFLFLCLLWAALRALLFSFYFKNCVTANTLGPFCFWLLYCFPVCLQFFTLSLMNLYFAQVIFKAKSKYSPELQKYRLPLYLLFLSISLLFLLVNLTCALLVKINRANTETVVLVRVTVNDSLFVLCAVSLSLCLYRIAKMSLANIYLEAKGTSVCQVTLIGVTVVLLYSSRACYNLVVLALTKIKSINSFDYDWYNVS--------------------------DQADLKSTLGDAGYVVFGVILFVWELLPTSLVVYFFRVRKPTLDRS-ASVIPGHMFSSRAYFFDNPRRYDSDDDLAWSIIPQNIQASFTSDSYDWSCRNNSFTAY--TEAEESHLAPEELNPY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::**** **:******* ****..** **.*****:*.************:***:*******:**:**::******:: *:**::.** ****************:******:************** ******** * ***:*********:*** . : :.:* ***::**:******:***:***:*:**********:**:****** *****:***:*******.:*:::: *.::********** ******. ******::***:*********:*********:** * : ..::*.* **.*:*****************.* **.:*..*:.* **. :.*** * * ::* * *:: . ", "identical_positions": 262, "similar_positions": 78, "identity": "61.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100721-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60478-1", "uniprot_id": "G137B_HUMAN", "id": "O60478-1", "name": "Integral membrane protein GPR137B", "aln": "MRPERPRPRGSAPGPMETPPWDPARNDSLPPTLTPAVPPYVKLGLTVVYTVFYALLFVFIYVQLWLVLRYRHKRLSYQSVFLFLCLFWASLRTVLFSFYFKDFVAANSLSPFVFWLLYCFPVCLQFFTLTLMNLYFTQVIFKAKSKYSPELLKYRLPLYLASLFISLVFLLVNLTCAVLVKTGNWERKVIVSVRVAINDTLFVLCAVSLSICLYKISKMSLANIYLESKGSSVCQVTAIGVTVILLYTSRACYNLFILSFSQNKSVHSFDYDWYNVSDQADLKNQLGDAGYVLFGVVLFVWELLPTTLVVYFFRVRNPTKDLTNPGMVPSHGFSPRSYFFDNPRRYDSDDDLAWNIAPQGLQGGFAPDYYDWGQQTNSFLAQAGTL-QDSTLDPDKPSLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BNQ3-1", "uniprot_id": "G137B_MOUSE", "id": "Q8BNQ3-1", "name": "Integral membrane protein GPR137B", "aln": "---------------MEAPPWEPVRNDSLPPTLSPAVPPYVKLGLTAVYTVFYALLFVFIYAQLWLVLRYRHKRLSYQSVFLFLCLFWASLRTVLFSFYFRDFVAANSFSPFVFWLLYCFPVCLQFFTLTLMNLYFTQVIFKAKSKYSPELLKYRLPLYLASLFISLVFLLVNLTCAVLVKTGDWDRKVIVSVRVAINDTLFVLCAISLSICLYKISKMSLANIYLESKGSSVCQVTAIGVTVILLYTSRACYNLFILSFSQIKNVHSFDYDWYNVSDQADLKSQLGDAGYVVFGVVLFVWELLPTTLVVYFFRVRNPTKDLTNPGMVPSHGFSPRSYFFDNPRRYDSDDDLAWNIAPQGLQGSFAPDYCDWGQQNNSFLAQAGTLHQDSTLDPDKASQG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B5S7-1", "uniprot_id": "A0ACD6B5S7_DANRE", "id": "A0ACD6B5S7-1", "name": "", "aln": "----------MRAAVMESPPSNSSP-PPPSSSLTPAVPPSVKLGLTALYTLFYCVLFIFVYAQLWLVLRYRHKRFSYQTAFLFLCLLWAALRALLFSFYFRDCGTANTLRPFCFWLLYCFPVCLQFFTLSLMNLYCAQVFFKAKSKFSPHLLRYKSPLYVLFFGVSLLFLLVNLSCALLVKMTDTPVKSVVLVRVAINDSLFVLCAVSLAVCLYKVAKMSIASIYLESKGTSVCQVTVIGLLVILLYSSRACYNLVVLSLTDVQSINSFDYDWYNVSDQADLRSSLGDAGYVVFGVILFIWELLPTSLVVFFFRVRKPAQDRSGS-AIPSHVFSNRPYFFDNPRRYDSDDDLAWPSHPVTTSTSLSTDCSDWGSRSSSFLVHLGGDDQRSTVVTAGLNR-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:** :. . ..:*:***** ******.:**:**.:**:*:*.************:***:.******:**:**::******:* :**:: ** ****************:***** :**:******:**.**:*: ***: : :**:******:**:*** : * :* *******:******:**::****::***:*.*******:******.**: *****:*******.:**::: :.::***************:..*******:***:**:******:***:*****:*::* :.. :*** ** *.***************** * . .::.* ***.:..***.: * * **: . . ", "identical_positions": 242, "similar_positions": 93, "identity": "60.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100721-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K046-1", "uniprot_id": "A0A0G2K046_RAT", "id": "A0A0G2K046-1", "name": "Myopalladin", "aln": "MQDDSIEASTSISQLLRESYLAETRHRGDNERSRAEPSSNPFHFSSP-GAAEGGG-PEDLPDLSAFLSQEELDESVNLARLAINHDPLERVDESQTRKRLSSDQ-----KPSFEPAFLQDSSRGLASSKDSPPETKRPQYSSETQSKKVFLNKAADFIEELSSLFKAHSSKRIRPRACKNHKSKTESPNKVVQENSPTFSDLTERRERTSVPIPIPADSRDNELNHAIEQREAKRREAELAAVEAAAGDSTPGSSPSSLYYEEPLGQPPRFTQKLRSREVPEGSRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGD------------------------------------------------------------------------------------------------PNKEEMNRIQKP----------------------------NEVSSPPTTSATIPPTV------------------QAQ-----PRVSTIQQCQSP--------------------------------------------------TNYLQGLNGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLAVRGNEDISD------------------------------------NETLHS------------------------------------------------------------------------------------------------DNSTTNPAATEQ---------------QPSP--------------------PNPQPPPEEQPPKP-------KLEGVLVNHNEPRSSSRIGLRVHFNLPEDDKDTE-------------------------------------------------ASSGCGMANTSQTRPDSFPERFNGQE---------ARISEPSSPVKEPPPVLAKPKLDSTQLQQLHNQVLLEQLQLHNTS---PSSPKESPFNTSILNS-APPTVTISSK----------------------------------------------------QVKSPAPQTFNLARPKHFFPASSTSTATVSP-------------------------SSSPVFTLSNTPQTIQRTVSKESLLMTHPSTQGR------SPGGLSIQNEPAP-----------------------------PSPAEP-----------------------------------------------------AVP-TVSYSITSGNQFQPHCVSPTPVSPT-GRIQNPVAFLSSVLPSLPSIPPTNAMGLPKSAPSVPPQGLMKKTTKTPQAVSDDYIRETKNSVILDLGKKVNFSD-----------------------------VRSHQQEYKISSFEQRLMNEIEFRLERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRRDGDGTCSLHIESTHGDDDGNYTIMAANPQGRISCSGHLMVQGFPIRNRLSPAGQSHRGRSRMQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYTCVATNKTGQNSFSLELTVVAKEVKKAPVILEKLQNSGVPEGHPVRLEGRVIGMPPPVFYWKKDNETIPFTRERISMHQDTTGYVCLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHQQIPTPISIR-PSGSRYGSLTSKGLDIFSAFSSMESTMMYSCTSRSVVESDEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5DTJ9-1", "uniprot_id": "MYPN_MOUSE", "id": "Q5DTJ9-1", "name": "Myopalladin", "aln": "MQEDSIEASTSISQLLRESYLAETRHRGDNERSRAEPSSNPFHFSGP-GAAEGGG-PEDLPDLSAFLSQEELDESVNLARLAINHDPLERVDEAQARKRLSSDQTKHASKPSFEPAFHQDSSRGPASPKDSPPETKRPQYSSETQSKKVFLNKAADFIEELSSLFKAHSSKRIRPRACKNHKSKTESQNKVLQENSPTFSDLTERRERASVPIPIPADSRDNELNHAIEQREAKRREAELAAGEAAAGDSTPGSSPSSLYYEEPLGQPPRFTQKLRSREVPEGSRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGD------------------------------------------------------------------------------------------------PNKEEMNRIQKP----------------------------NEVSSPPTTSAAIPPAA------------------EAQPLAAQPRVSTVQQCQSP--------------------------------------------------TNYLQGLNGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFSEDSGCFTCTASNKYGTVSSIAQLDVRGNEDISD------------------------------------NGALHS------------------------------------------------------------------------------------------------ANSTTNPAVAEH---------------QPSP--------------------LNPQPLSEEQPPKP-------KLEGVLVNHNEPRSSSRIGLRVHFNLPEDDKDME-------------------------------------------------ASSGSGAANTSQTRPNSFPERFNGQE---------ARIPEPSSPIKEPPPVLAKPKLDSTQLQQLHNQVLLEQQQLQNTS---PSSPKES-LHMSALNS-APPAVTISSK----------------------------------------------------QVKGPAPQMFNLARPKHFFPASSTSTATVSP-------------------------SSSPVFTLSNTPQTIQRTVSKESLLMAHPSTQGR------SPGGLSIQNEPAP-----------------------------PSPAEP-----------------------------------------------------AAPPTAAYSIPSGNQFQPHCVSPTPVSPT-GRIQNPVAFLSSVLPSLPSIPPTNAMGLPKSAPSVPSQGLMKKTTKAPQAVSDDYIRETKNSVILDLGKKVNFGD-----------------------------VRSHQQEYKISSFEQRLMNEIEFRLERTPVDESDDEIEHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTHGDDDGNYTIMAANPQGRISCSGHLMVQGLPIRSRLSPA-LSHRGRSRMQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYTCVATNKTGQNSFSLELTVVAKEVKKAPVILEKLQNSGVPEGHPVRLEGRVIGMPPPVFYWKKDNETIPFTRERISMHQDTTGYVCLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHQQIPTPISIR-PSGSRYGSLTSKGLDIFSAFSSVESTMLYSCTSRSVVESDEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86TC9-1", "uniprot_id": "MYPN_HUMAN", "id": "Q86TC9-1", "name": "Myopalladin", "aln": "MQDDSIEASTSISQLLRESYLAETRHRGNNERSRAEPSSNPCHFGSPSGAAEGGGGQDDLPDLSAFLSQEELDESVNLARLAINYDPLEKADETQARKRLSPDQMKHSPNLSFEPNFCQDNPRSPTSSKESPQEAKRPQYCSETQSKKVFLNKAADFIEELSSLFKSHSSKRIRPRACKNHKSKLESQNKVMQENSSSFSDLSERRERSSVPIPIPADTRDNEVNHALEQQEAKRREAEQAASEAAGGDTTPGSSPSSLYYEEPLGQPPRFTQKLRSREVPEGTRVQLDCIVVGIPPPQVRWYCEGKELENSPDIHIVQAGNLHSLTIAEAFEEDTGRYSCFASNIYGTDSTSAEIYIEGVSSSDSEGD------------------------------------------------------------------------------------------------PNKEEMNRIQKP----------------------------NEVSSPPTTSAVIPPAVP-----------------QAQHLVAQPRVATIQQCQSP--------------------------------------------------TNYLQGLDGKPIIAAPVFTKMLQNLSASEGQLVVFECRVKGAPSPKVEWYREGTLIEDSPDFRILQKKPRSMAEPEEICTLVIAEVFAEDSGCFTCTASNKYGTVSSIAQLHVRGNEDLSN------------------------------------NGSLHS------------------------------------------------------------------------------------------------ANSTTNLAAIEP---------------QPSP--------------------PHSEPPSVEQPPKP-------KLEGVLVNHNEPRSSSRIGLRVHFNLPEDDKGSE-------------------------------------------------ASSEAGVVTTRQTRPDSFQERFNGQA---------TKTPEPSSPVKEPPPVLAKPKLDSTQLQQLHNQVLLEQHQLQNPP---PSSPKEFPFSMTVLNSNAPPAVTTSSK----------------------------------------------------QVKAPSSQTFSLARPKYFFPSTNTTAATVAP-------------------------SSSPVFTLSSTPQTIQRTVSKESLLVSHPSVQTK------SPGGLSIQNEPLP-----------------------------PGPTEP-----------------------------------------------------TPP-PFTFSIPSGNQFQPRCVSPIPVSPT-SRIQNPVAFLSSVLPSLPAIPPTNAMGLPRSAPSMPSQGLAKKNTKSPQPVNDDNIRETKNAVIRDLGKKITFSD-----------------------------VRPNQQEYKISSFEQRLMNEIEFRLERTPVDESDDEIQHDEIPTGKCIAPIFDKRLKHFRVTEGSPVTFTCKIVGIPVPKVYWFKDGKQISKRNEHCKMRREGDGTCSLHIESTTSDDDGNYTIMAANPQGRISCSGHLMVQSLPIRSRLTSAGQSHRGRSRVQERDKEPLQERFFRPHFLQAPGDMVAHEGRLCRLDCKVSGLPPPELTWLLNGQPVLPDASHKMLVRETGVHSLLIDPLTQRDAGTYKCIATNKTGQNSFSLELSVVAKEVKKAPVILEKLQNCGVPEGHPVRLECRVIGMPPPVFYWKKDNETIPCTRERISMHQDTTGYACLLIQPAKKSDAGWYTLSAKNEAGIVSCTARLDIYAQWHHQIPPPMSVR-PSGSRYGSLTSKGLDIFSAFSSMESTMVYSCSSRSVVESDEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A9B6-1", "uniprot_id": "A0AB13A9B6_DANRE", "id": "A0AB13A9B6-1", "name": "Myopalladin", "aln": "MQENSMDQPTSLSQLLRESYLAESRAHHRHGESTDPPRRLVYGTLKEKNQESCAKLDTPIPDLSAFLNQEELDKSVDLACKAISDDPQER-DQKSAKPQIESTP----------KKVQENTHR--TNVADFKRAQRTAPYGMETQSKKEFLNKAADFIEELSSLFKANSSKRIRPRSCKAHRSRYQNKP---QPDGASFSVNAEDRERP--------------VIQPMEETMEDTREPEPTAAGTVCESTDMVQSES---LEEPECEPPQFIQKLKSREVAEGSKVQLDCIIRGKPAPEVRWFCEGKELENSPDIQIITDGERHSLIIAEAFEEDTGRYSCFASNFYGTDSTSAEIYIEGASSSDSDGEQHYPAQLHKRSQPKPAVVSVESSSSLEDTTSTVTITCAEAPAPEAVPLTKLTPDQPLQPEETEPQSFEIFSSATPVEHPIVPFPEPVIEPALPVLEPVKEPTISVLEPTIEPTISVLEPTISVLESVIEPAISVLEPTISLAEPTISVLEPTIEPTVSVLEPTISLLGPVIEPAILAVEPTISVLESTISVREPVIEPTIPVLEPPTPILEVEPSPPPSSQSIPDLLLTSQQSISESLNGSSSYVQSFDVRPMMAAPVFTKNLQDVLALESQLVVLECRVKGVPSPKVDWYREGMLIDDSPDFRILQKKPRSMAESEEICTLVIAEVFPEDSGTFTCTASNKYGTVSSTANLSVKGHNNNTTNAKKTSMLTVESSLPKVPTTDLISTTLTRKPDLPLVNNKLHSSMICLDPLNSGFKQSYPLDGGTFRSDSLNTSTLRHDLSTSLPSLNPISIGKYSSDTLRSRLPQTDPLGFSAFSPNSDLTHKPLSSSTPHFDSGGSGFNSSTDVTQSPPNGLASSITLSTDTCLEPSPNASKSILSPCITSPPLLNSNNHQERPPVKPLPDPPTSCLKTRPEGVLGNHNESRSSSRVGLRVTFKLPEDEEEEEKGLSSKGPPPVLAKPKLDPSQLQILHNQVLLEQRQDNVSPSLESQHLDETSCEALPITPTQLSVNPFPSAFRPTPNVMDSGPFPQLIPASIPPPPAGPAPILKATPASQFSISLPNSMPLPQLTPSTTLNILPSSPQQNMVPTTFMNTDAPITVPSTSIPQSIVMHKAVPISPILAPMPNVIPTTPITQSAGAPNIPQSNVGPSTHFPQLIMVPSTQPNLSHLANVSPITPSTHTSQINSNPNLQMSAPKMQALTTPDVALVNNTKLNSTSVTYPSMTPHSPSVVYPSLSNITSPPMGRNRPTPSPMSPPPLTDTQLPLPGIIPISTQSFSYTRPKEFIAAQALSPIRGPSPTESPVPMLHELAAQIFPKTTRDLTSPINQLPPFPRKFPTRVLEGPSSPPYVSSPPLNPPGLVNSVFSFRTQSPPQASSPTSSSSSPSPIQNPVAFLSSVLPSLPTSPPTNAMGLPMRAPPGP-QSALKRSQRGSRLISDDEIRDSKELLLQDIEKKLQFRDEPLRFGQQKPMCFVGEMRHPLGPNIPTATVINYDEEYKVSSFEQRLMSEIEFRLERTPVEESDDEVQHDEIPTGKCIAPIFDKKLKHFRAVEGIPVTFTCKVVGIPIPKVYWFKDGKQILKKNEHYRKIREGDGTCSLHIETVTNDDDGNYTVMAANPQGRISCSGHLIVQTGPVRNR--PVVHSQRVRARVQEVEGEPTQERFFRPHFLQAPGDMLAHEGRLCRLDCKVSGLPHPEIMWLLNGKPIYPDVTHRMLVRENGIHSLVIDPLTQADDGTYTCIASNKAGQSSFCLQLKVVEKEMKAAPRFVEKLQNTGIAEGAAVRLECRVAGMPQPVIYWKKDNDTIPHSRDRVSMHQDTTGYVCLLIQPTRKEDAGWYTVSAKNEAGIISCTARLDIYAQWHQHVHPPMKKSSLTGSRYAALTGQGLDIKSAFPMSESGPHVLFRER---ESDEL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::*:: .**:***********:* : : .* * . . . :*******.*****:**:** **. ** *: *: .:: ::.. . ::. * :. : : . * ****** *****************::********:** *:*: :. * :..:** :* ***. : :.:*: . **.* :* :. .: .* * *** :**:* ***:****.**::******: * *.*:***:************:*: *: *** ******************:**************.*****:*: * ** : :* :* . .* :.: *: :. * ::.::. * :.*:*.:: :*::******* **:: * *.****:******.*****:***** **:*****************.************.**** ************** *:* *:*::: : * *** **:*: : :*** : : . : *.* : **** ****.*****:**** *:****:: * :*. . .. * :.* . *. . . .* *. : *.. * .* *.: * * .. ****:: . : :*: ** :*. :* * .. .: **. . : *:: *: . * .*:.* * **:: . . .. * : : * : : ** *: : * * *.*:*. * :. .* *:. ** . *.: . ****************: ********* **. * *. *:. : .: :.** **::*: :: *: **: * * * ::***:********.***********:*****::****************:*****..** *******:****:************ *:*** : *:**********:. .*******:***************:** *:*.* .. *:* *:*:** : ** ****************:***************** **: *****:*: **.:*:*****.*:***:****** * ***.*:*:**:**.**.*:*.** **:* ** ::***** *:.** .**** ** *** **:******:*** :*:*:*********.******::*.******:********:*************::: .*:. :****.:**.:**** ***. ** .* *****", "identical_positions": 692, "similar_positions": 296, "identity": "35.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100721-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NYW1-1", "uniprot_id": "TA2R9_HUMAN", "id": "Q9NYW1-1", "name": "Taste receptor type 2 member 9", "aln": "--------------------MPSAIEAIYIILIAGELTIGIWG---NGFIVLVNCIDWLKRRDISLIDIILISLAISRICLLCVISLDGFFMLLFPGTYGNSVLVSIVNVVWTFANNSSLWFTSCLSIFYLLKIANISHPFFFWLKLKINKVMLAILLGSFLISLIISVPKNDDMWYHLFKVSHEENITWKFKVSKIPG-----TFKQLTLNLGVMVPFILCLISFFLLLFSLVRHTKQIRLHATGFR---------DPSTEAHMRAIKAVIIFLLLLIVYYPVFLVMTSSALIPQGKLVLMIGDIVTVIFPSSHSFILIMGNSKLREAFLKMLRFVKCFLRRRKPFVP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GL09-1", "uniprot_id": "A0AC58GL09_DANRE", "id": "A0AC58GL09-1", "name": "", "aln": "MNAPQKTILTCSERAAAFEGVRRGAQALLIVEVINNIITLILNGITGNFWLALRSLPRSRSR-LRPNDVLFINLAVSNLITNCMVDLPDTLAQFLNSWLLSRNYCSVLQFSSDLSETSSIFSTMFITLYWHQKLVGSVRRGGAPVQLDNLRLVLWLLLGSWMVALTFSVP-------HFFIAEHDGNDSLEVCEEKFPTPAEKKTFDGLYLIVANVVPLVGITYASVQIVVTLIQSQKRVKDHSGGSEQKTEVRSSGNPSSGTHVRAAKSVVAVASIFIFCWFIHLVLRIYSGFRNSILVVKLTNFIGATYTCFVPYVYLHG--------VKKLNCSCCW---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :*: *: : .:: * . ..* : :..: : * : *:::*.**:*.: *::.* . : :: . . *:::. :::.**:: * ::::: *:.. : ::*. :::* :****::::* :*** *:* ..*: * : :. .*:* **. * * :. :**:: : . ::.:*:: *::: *: * . :**: :*:** *:*: . ::*. : :.**: : : :. **: : ::: . :.. .:: : * :* *. *: ", "identical_positions": 59, "similar_positions": 128, "identity": "16.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100721-9", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "L7N217-1", "uniprot_id": "L7N217_MOUSE", "id": "L7N217-1", "name": "", "aln": "----------MKKLCVFILFFMLLKFSLISHHLTE--PICFWRIKNNEDNDGDLRSDCGFFLAAVEGPIDQ-IYN-ISNF-----------------------------------------------RIPARRYEFFLVLFFATDEINKNPYLLPNMSLISPIASG--QCEKTLENLDKIYSEKNHTVQFTDNICVFYETCYISLIGPSWKTSVKLS-------------IHHG----TPRV--------FFGPFNPKLSNHDLFPNVHQVATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQCIQFLSDLREEMQGHGICLAFVNMIPEDMQLYMTRAEIYDKQIMESTAKVVIIYGEMNSTLEVSFRRWEDKGVRRIWIATLQWDVITNKKD-FTLDFFQGTVTFAHHVGDIANFRNFLQTMNNEKYPINISESILQWNSFNCSFSKNSN-KKDHFTFNNTLEWTALHIYNMVLSEEGYNLYNAVYAVAHTYHELILQQVESQQTEVPKGTFTDCQQVSSMLKSRIFTNPFGELVNMKHQESQCADYDIFIIWNFPKGLGLKVKIGYYLPCYQRSQQLHI-YDLEWATGGTL----VPSSMCSVACTAGFRKIHRKQTADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPLGMALGCMALFLSALMVLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCPLLFIGHPNLATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRG-MLASGAPNLVIPICTLIQLVLCGIWLVTSPPFIDRDTQSEYGKTIIICNKGSVIAFHFVLGYLGALALGSFTVAFLARNLPDRFNEAKFLTFSMLVYCSVWITFLPVYHSTRGAVMVVVEVFSILASSAGLLGCIFLPKCCVILLD---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "L7N1X2-1", "uniprot_id": "L7N1X2_MOUSE", "id": "L7N1X2-1", "name": "", "aln": "----------MKELCVFILCFLLLKFSLILCHLTE--PICFWRIKSNEDNDGDLRSDCGFFLAAVEGPIDQ-IYN-ISDF-----------------------------------------------RIPARRYEFFLVLFFATDEINKNPYLLPNMSLISPITSG--QCEKTLGDLDKIYSEKNITVEFTDNICVFYGACYISFIGPSWKTSVKLS-------------IHTG----TPRV--------FFGPFNPKLSDHDQFPYVHQVATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGIQFLSDMREEMQRDGICLAFVNMIPGNMQLYMTRAKIYDKQIMESTAKVVIIYGEMNSTLEVGFRRWIHLGVRKIWITTSQWDVVTNKKD-FSFNFFHGTVTFAHHIGELVKFRNFLQTMNNEKYPVNISETRLGWNSFNCSISKNSN-KKDHFTFNNTLEWTARNNFDMVLSEEGYNLYNAVYAVAHTYHELILQQVESQQMAVPKGIFTDCQQVASLLKTRVFTNPVGELVNMKHRENQCADYDIFIIWNFPKGLGLKVKIGSYLPCFHQSQQLHISEDLEWATGGTS----VPSSMCSVTCTAGFRKIHQKQTADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANVEKTHCLQRVVSFLAYEDPLGMALGCMALSFSALTVLILVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQITFGVFFTVAISTVLAKTITVVLAFKLTTPGRRMRG-MLASGAPNLAIPICTLIQLVLSGIWLVKSPPFIDRDTQSEHGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCVILD----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "K7N621-1", "uniprot_id": "K7N621_MOUSE", "id": "K7N621-1", "name": "", "aln": "----------MKNLCVFTLSFFLLEFSLILCHLTE--PICFWRINNNEDNDGDLRSDCGFFLAAVEGPTDD-SYN-ISDL-----------------------------------------------RIPARRYEFFLVMFFATDEINKNPYLLPNMSLIFPINHG--QCEKTLGDLDKIYSEKNYTVEFTDYICVSFGTCFIALIGPSWKTSIKLS-------------INSG----TPRV--------FFGPFNPKLSDHDQFPYVHQVATKDTRLSHAMVSLMFHFTWIWIGMVISDDDQSIQFLSDMREEMQRHGICLAFVNMIPEDMQLYMTRATIYDKQIMESTAKVVMIYGEMNSTLEVSFRRWEDLSIRRIWITTSQWDVITNKND-FSLDFFQGTVTFAHHVGEIANFRNFLQTMNSEKYTVNISESRLGWNYFNCSISKNSN-KKDHFTFNNTLEWTTLHKYDMVLSEEGYNLYNAVYAVAHTYHELVLQQVESQQMTVPKGTFTDCQQVSSMLKSRIFTNPVGELVNMKHRENQCTEYDIFIIWNFPQGLGLKVKIGSYLPCFQQSQQLHISEDLEWATGGSS----VPPSLCSVTCTAGFRKIHQKQTADCCFDCDQCPENAVSNETVDMEQCMRCPDDKYANLEKTHCLQRAVSFLAYEDPLGMALGCTALSFSALTVLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRG-MLASGAPNIVIPICTLIQLVLCGIWLVTSPPFIDRDMQSEHGKTIIICNKGSVIAFHFVLGYLGALALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTQGTVMVVVEVFSILASSAGLLGCIFLPKCCVLLRIQNSNFLHKYKHELHS------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "L7N2A0-1", "uniprot_id": "L7N2A0_MOUSE", "id": "L7N2A0-1", "name": "", "aln": "----------MKKLRVFTFSLLLLKCFLISCHLTE--PICFWRLKNNEDNDGDLRSDCGVFLAAVEGPIDQ-IYN-ISDF-----------------------------------------------RIPARRYEFFLVMFFATDEINKNPYLLPNMSLISPVDHG--QCEETLGLLDEIYLEKNNSVEFTDYICVFYGTCYIGLIGPSWKTSVKLS-------------IHSR----TPRVRMCETRLVFFGPFNPNLSDHDQFPYVHQVAIKDTHLSHGMASLMLHFRWTWIGLVISDDDQSIQFLSDLREEMQRHGICLAFVNMIPEDMQLYMTRAKIYDEEIMTSTAKVVIIYGEMNSTLQVSFRRWEDLGVRRIWITTSQWDVITNKND-FSLDFFHGTVTFAHHVGKIAKFRNFLQTMNSDKYPVNISKSILGWNYFNCSVSKKGN-KKDHFTFNNTLEWTALHNFDIVLSEEGYNLYNAVYAVAHTYHELILQQVESQQTAVPKGIFTDCQQVSSMLKSRIFTNPVGELVNMKHRENQCADYDIFIIWNFPQGLGLKVKIGNYLPCYPWSQQLHISENLEWATGGSS----VPSSMCSVTCTAGFRKIHQKQTADCCFDCDQCPENEVSNETADMEQCVRCPDDKYANLEKTQCLQRVVSFLAYEDPLGMTLGCMALTFSALTVLVLVIFVKYKDTPIVKANNRIVSYILLISLVFCFLCSLLFIGHPTQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGGRMRG-MLASGAPNLVIPICTLIQLVLCGIWLVTSPPFIDRDIQSEHGKTIIICNKGSVIAFHFVLGYLGALALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCVILLRPDLTFLQKYKDKLPS------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9Q759-1", "uniprot_id": "E9Q759_MOUSE", "id": "E9Q759-1", "name": "", "aln": "----------MKNLRGFGLSFMLLKFSLIWCHLTE--PICFWRIKNNEDNDGDLRSDCGFFLAAVEGPIDH-TYN-ISDF-----------------------------------------------RIPARRHEFFLVLFFATDEINKNPYLLPNMSLIFPEDPG--QCEKLLGELDKIHSEAKFTVDFTDYICAGYGTCYIGLIGPSWKTSVKLS-------------TNSG----TPRV--------FFGPFNPKLSDHDQFPYVHQVATKDTHLSHGMITLMLHFRWTWIGLVISDDDQGIQFLSDLREEMQRHGICLAFVNMIPEDMQLYMTRAKIYDKQIMESTAKVVIIYGEMNSTLEVSFRRWEDLGARRIWITTSQWDVITNKND-FSLDFFHGTVTFEYHHSEIAKFKNFMKTMNTDKYPVNISESILRWNYFNCSTSMNSYSKMGHFTFNNTLEWTALHNFDMALSEEGYNLYNAVYAVAHTYHELILLQVESQQTEEPKGTFTDCQQVSSTLKSRIFTNPVGELVNMKHRENQCADYDIFIIWNFPQGLGLKVKIGSYLPCFPQSQQLHISEDLDWATGGSS----VPSSLCSVTCTAGFRKIHQKQTADCCFDCDQCPENAVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPLGMALGCMALTFSALTVLVLVTFVKYKDTPIVKANNRILSNILLISLVFCFLCPLLFIGHPNKATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTSPGGKMRG-MLASGAPNLVIPICTLVQLVLCGIWLVTSPPFIDRDTQSEHGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFVPKCFVILVRPDSNFLQKYKDKLFY------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "L7N472-1", "uniprot_id": "L7N472_MOUSE", "id": "L7N472-1", "name": "", "aln": "----------MKKLRTFTISFLLLKFSLILCHVTD--PICFWRIKNNEENDGDLRSDCNFLLWTDYESTEFNFYN-IVDF-----------------------------------------------RIPARRYEYFLVLFFATDEINKNPDLLPNMSLIVWLLSG--QCGDEWSVLHKNYSQENINVKFINYDCLSP-ACYIDLTGPSWKTSLKMS-------------IQSR----TPKV--------FFGPFNPDLRDHDQFPFVHQVATKDTYLSHAMVSLMHHFRWMWIGLVISDDDQGIQFLSDLREEMQRHGICLAFVNMIPENMQIYMTRATIYDKQIMESTAKVVIIYGEMNSTLEVSFRRWEDLGVRRIWITTSQWDVITNKND-FSLDFFHGTVTFEHHHSEIAKFKNFMKTMNTDKYPVNISQSIVGWNYFNCSTSMNSFSKMDHLTFNNTLEWTALHNFDMVLSEEGYNLYNAVYAVAHTYHELILLQVESQQTEVPKGIFTDCQQVASMLKSRIFTNPIGELVNMKHRENQCADYDIFIIWNFPQGLGLKVKIGSYLHCFSQSQQLHISEDLEWATGGTS----VPSSLCSVTCTAGFRKIHQNETADCCFDCDQCPENEVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPWGMALGCMALFLSALTVLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRG-MLASGAPNLVIPICTLIQLFLCGIWLVTSPPFIDRETQSEYGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCVILVRLDSNFLQKYKDKLPS------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "K7N6Z8-1", "uniprot_id": "K7N6Z8_MOUSE", "id": "K7N6Z8-1", "name": "", "aln": "----------MKKLRTFTISFWLLKFSLIFCHVTE--PICFWRIKNNEENDGDLRSDCNFFLWTYDESTEINFYN-IVDF-----------------------------------------------RIPARRYEFFLVLFFATDEINKNPDLLPNMSLIVWLLGG--QCGDEWSVLYKNYSQENINVEFINYDCLSP-DCYIHLTGPSWKTSLKMS-------------IQSR----TPKL--------FFGPFNPNLSDHDQFPYVHQVATKDTHLSHAMVSLMLHFRWAWIGLVISDDDQGIQFLSDLREEMQRHGICLAFVNMIPKDMQIYMTRATIHDKQIMESTAKVVIIYGEMNSTLEVSFRRWEDLGARRIWITTSQWDVITNKND-FSLDFFHGTVTFEHHHSEIAKFKNFMKTMNTDKYPVNISQSIGGWNYFNCSTSMNSYSKMDHLTFNNTSEWTALHNFDIVLSEEGYNLYNAVYAVAHTYHELILLQVESQQTEVRKGIFNDCQQVSSMLKSRIFTNPVGELVNMKHRENQCAEYDIFIIWNFPQGLGLKVKIGSYLPCFQQSQQLHISEDLDWATEGTS----VPSSMCSVTCTAGFRKIHQNETADCCFDCDRCPENEVSNETADMEQCVSCTGDKYANLEKTHCLQRAVSFLAYEDPLGMSLGCIALFLSALTSLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRG-MLASGAPNLVIPICTLIQLVFCGIWLVTSPPFIDRDTQSEYGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCAILVRLDSNFLQKYKDKLPS------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9Q4X4-1", "uniprot_id": "E9Q4X4_MOUSE", "id": "E9Q4X4-1", "name": "", "aln": "----------MKKLRTFTISFWLLKFSLILCHVTE--PICFWRIKNNKDNDGDLRSDCNYFLWTFEETTEINFYN-IVDF-----------------------------------------------RIPTRRYEFFLVLFFATDEINKNPDLLPNISLIFWLFGG--QCEDEWGVLDTNYSQNNINVKFINYDCLSP-NCYIDLTGPSWKTSLKLPNIL----TIIVLMWMSHPLFYILQV--------FFGSFNPNLSDHDQFPYVHQVATKDTLLSHAMVSLMLHFRWTWIGMVISDDDQGIQFLSDLREEMQRHGICLAFVNMIPENMQIYMTRAKIYDKQIMESTAKVAIIYGEMNSSLEVSFRRWEDLGVRRIWITTSQWDVITNKND-FSLDFFHGTVTFEHHHSEIAKFKNFMQTINTDKYPVNISESILGWNYFNCSTSMNSYSKMDHLTFNNTSEWTALHKYDMALSEEGYNLYNAVYAVAHTYHELILLQVESQQMAVPKGTFTDCQQVSSMLKSRIFTNPVGELVNMKHRENQCADYDIFIIWNFSQGLGLKVKIGSYLHCYPRSQQLHISEDLEWVTGGSS----VPSSMCSMTCTAGFRKIHQNETADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPLGIALGCMALFLSALTVLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRG-MLASGAPNLVIPICTLIQLVFCGIWLVTSPPFIDRDTQSEYGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCVILVRLDSNFLQKYEHKLPS------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PYF5-1", "uniprot_id": "E9PYF5_MOUSE", "id": "E9PYF5-1", "name": "", "aln": "----------MKKLCVFTISFLLMTFSLFLCSLTG--PSCFWRIQNNEDNDGDLHRDCGFFLFTSEEPIKEDFYHFCIDF-----------------------------------------------RIPARRYEVFLVMFFATDEINRNPYLLPNMSLIFCLIVG--MCGDTLGYLEETHSP-NNTWNSINYNCEIRPICDIELTGPSWTTSVKLA-------------INSR----KPKV--------FFGPFNSHLSDHDQFPYIYQVATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQSIQFLSDLREAMQRHGICLAFVNMIPENMQIYMTRGKIYDKQIMTSSAKVVIIYGEMNSTLEVSFRRWAYLCARRIWITTSQWDVITNKRD-FSFDFFHGTVTFAHHNGEIVIFRNFLQTVNTSKYPLDISQTMQEWNYFNCSISKNSNSKMDHFTFNNTLEWTALQKLNMVLSEEGYNLYNAVYAVAHTYHELILQQVEFQKMAEPKGIFTDCQQVASLLKTRVFTNPVGELVNMKHRENQCADYDIFNIWNFPQGLGLRVKIGSYYPCFPQNQQLHISEDLEWATGGTS----VPTSMCSVTCTAGFRKIHQKQTADCCFDCAHCPENEVSNETADMEQCVRCPDDKYANLEQTHCLQRAVSFLAYEDPLGMALGCMALCFSALTLLVFFTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVVMAFKLTAPGRRVRG-MLVAGAPNLAIPICTLIQIVLCGIWLVTSPPFIGRDTKSEHGKTILICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLMFCSVWITFLPVYHSTRGKAMVVVEVFSILASSAALLGFIFVPKCYVILVKSDSNFREKYKNKFHY------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A3B2WCY4-1", "uniprot_id": "A0A3B2WCY4_MOUSE", "id": "A0A3B2WCY4-1", "name": "", "aln": "----------MKKLHAFTISFSLLKFSLILYSLTE--PNCFWRIQSNEDNDGDLRSDCGFVLFTYEGPIEEKFYNNVIHFSGTMNNLDLIWNAQQSRNGGHTCDPDLEDGRSSLLIWMLKNSGHEKHRIPARRYEFLLVMYFATDEINRNPYLLPNMSLIFSLIVG--MCEDTLGYIEEKYSPQKNRLNFINYNCGIPQTCNIQITGPSWTTSLKLA-------------INSR----RPKV--------FFGPFNPNLSDHDQFPYVHQVSTKDTHLSHAMVSLMLHFKWTWIGLVISDDEQGIQFLSGLREEMQTYAICLAFVNMIPETMQIYMTRADIYDKQIIESTAKVVIIYGEMNSTLEVSFRRWGYLGARRIWITTSQWDVITNEKD-FSLDFFHGTITFAHHNGRIAKFNNFLQTMNTSKYPIDVTQTMQDWNYFNCSIFKNSVRKTGQFIFNNTLEWTTQHKIDMVLSEEGHNLYNAVYAVAHTYHELILQQVESQKMPKLKGVFSDCHQVASLLKTRVFTNPVGELVNMKHRENQCADYDIFNIWNFPQGLGLKVKIGSYFPCFPQSQQLCISENMEWATGGAL----VPTSMCSVTCAAGFRKIHQKHTADCCFDCVLCPENEVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPLGMALGSMTMCFSALTVLVLVTFVKYKDTPIVKANNRILSYILLISLILCFLCSLFFIGQPNHATCILQQTTFGVFFTVAISTVLAKTITVVMAFKLTTPGRRMRG-MLASGTPNLVIPICSLVQLVLCGIWLVTSPPFIDRDTQSEHGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFVPKCFVILVRPDSNFLQKYKDKLFY------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A3Q4EIC8-1", "uniprot_id": "A0A3Q4EIC8_MOUSE", "id": "A0A3Q4EIC8-1", "name": "", "aln": "----------MKKLCAFTISLLFLKFSLILCCWSE--PSCFWRIKNSDDNDGDLQRECHFYLGAADTPVEDNFYSSLLKFR-----------------------------------------------IAASEYEFLLVMFFAIDEINRNPYLLPNITLMFSFIGG--NCQDLLRVMDQAYTQINGHMNFVNYFCYLDDSCAIGLTGPSWKTSLKLA-------------MHSS----MPLV--------FFGPFNPNLRDHDRLPHVHQVAPKDTHLSHGMVSLMFHFRWTWIGMVISDDDQGIQFLSDLREESQRHGICLAFVNMIPENMQIYMTRATIYDQQIMTSSAKVVIIYGEMNSTLEVSFRRWEELGARRIWITTSQWDVITNKKD-FTLNLFHGTITFAHHRVEIPKLNKFMQTMNTAKYPVDISHTILEWNYFNCSISKNSI-RMHHITFNNTLEWTSLHNYDMAMSDEGYSLYNAVYAVAHTYHEYIFQQVESQKKAKPKRYFTACQQVSSLMKTRVFMNPVGELVNMKHRENQCTEYDIFIIWNFPQGLGLKVKIGSYLPCFPQRQKLHISDDLEWAKGGTSP--QVPSSVCSVACTAGFRKIYQKETADCCFDCVQCPENEISNET-DMEQCVRCPDDKYANIEQTHCLSRAVSFLAYEDPLGMALGCMALSFSAITILVLVTFVKHNDTPIVKANNRILSYILLISLVFCFLCSLLFIGPPDQVTCILQQTTFGVFFTVSVSTVLAKTITVVMAFKLTTPGRRMRG-MMMTGAPKLVIPICTLIQLVLCGIWLVTSPPFIDRDIQSEHGKIVILCNKGSVIAFHVVLGYLGSLALGSFTLAFLARNLPDTFNEAKFLTFSMLVFCSVWITFLPVYHSTRGRVMVVVEVFSILASSAGLLMCIFVPKCYVILIRPDSNIIKKHKGKVLN------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2BE32-1", "uniprot_id": "A2BE32_MOUSE", "id": "A2BE32-1", "name": "", "aln": "----------MKKLCAFTISFLFLKFSLILCCLSE--PSCFWRIRNSEDSDGDLQRECHFYLWLIDESIEDNFVSDLN-FR-----------------------------------------------IAASEYELLLVIFFATDEINKNSYLLPNMTLMFSIIGG--NCHDLLRSLDQEYTEIKGHMNFVNYFCYLDDSCAIGFTGPSWKTSLKLG-------------LHSS----MPLV--------FFGPFNPNLRDHDRLPHVHQVATKDTHLSHGMVSLMFHFRWTWIGLVISDDDQGIQFLSDLREESQRHEICLAFVNMIPENMQIYMTRATIYDKQIMTSSANVVIIYGEMNSTLEVSFRRWEELGAWRIWITTSQWDVIKNKKE-FTFNLFHGTITFAHHKVEIPKFKKFMQTMNTAKYPVDISHTILEWNYFNCSISKNSS-KMDHMTFNNTLEWTALHNYDMAMSDEGYNLYNAVYAAAHTYHEHILQQVESQKKAKPKRYFTACQQVSSLMKTRVFSNPVGELVNMKHRENQCTEYDIFIIWNFPQGLGLKVKIGSYIPCFPKSQQLHICDDLEWAMGGT-----VPSSVCSVACTAGFRKIHQEETADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANIEQTHCLSRAVSFLAYEDPLGMALGCMALSFSAITILVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQVSCILQQTIFGVFFTVSVSTVLAKTITVVMAFKLTTPGRRIRG-MMMTGAPKLVIPICTLIQLVLCGIWLVTSPPFIDRDIQSEHGKTVILCNKGSVIAFHVVLGYLGSLALGSFTLAFLARNLPDTFNEAKFLTFSMLVFCSVWITFLPVYHSTRGRVMVVVEVFSILASSAGLLMCIFVPKCYVILIRPDSNFIKKHKGKLLN------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "K7N5U4-1", "uniprot_id": "K7N5U4_MOUSE", "id": "K7N5U4-1", "name": "", "aln": "----------MKQLCAFTISFLLLKFSLILCCLTE--PICFWRIKNSEDDDRDLQRECHFYLWAIDKPIEDDFYNIVYNFR-----------------------------------------------IAASEYEILLIMFFATDEINKNPYLLPNITLIFTIIGG--HCHDLLGGLDEAYTQINGRVKFVNYFCYSDDSCLIGLTGPSWKTSLKLA-------------MDSS----MPMV--------FFGPFNPNLCDHDRLPHVHQVAPKDSHLSHGMVSLMFHFTWTWIGLVISDDNQGIQFLSDLRKEMQRHGICLAFVNMIPENMQIYMTRATIYDKQIMTSSAKVVIIYGDMNSTLEISFRRWEDLGAQRIWITTSQWDVITNKKD-FTLNLFHGTVTFAHYKGEIPKFRNFMQTINTDKYPVDISHTILEWNYFNCSSSKNSS-KMDHFTFNNTLEWTALHKYDMALSEEGYNLYNAVYAAAHTYHEHFLQQAESQKRADPKRDFTECQQVSSLLKTRVFTNPVGELVNMMHGENECTEYDIFIIWNFPQGLGLKVKIGSYLPCFPQSQQLHISDDLEWAMGGTS----VPSSMCSMTCTAGFRKIHQKETADCCFNCVPCPENEVSNETADMEQCVMCPDDKYANIEQTHCLQRTVSFLAYEDPLGMALGCMALSFSAITTLVLVTFVKYKDTPIVKANNRILSYILLISLDFCFLCSLLFIGHPTQVTCILQQTTFGVFFTVAVSTVLAKTITVVMAFKLTTPGRRMRG-MMMTGAPKLVIPICTLIQLVLCGIWLVTSPPFIDRDIKSEHGKTVILCNKGSVIAFHFVLGYLGFLALGSFTVAFLARNLPDRFNEAKFLTFSMLMFCSVWITFLPVYHSTRGKVMVAVEVFSILASCAGLVGCIFFPKCYVILIRSDSIFIQKYKDELHY------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3YWE3-1", "uniprot_id": "D3YWE3_MOUSE", "id": "D3YWE3-1", "name": "", "aln": "----------MKKMCALTISFLLLKFSLILCCLKE--PICFWRIKSSEYNDGNLQSECGYFVWTMKKLMKDDFYNVWLDFR-----------------------------------------------IPASEYEFVLVMFFATNEINKNPDLLPNTSLVFSVMAG--NCQDSLGNLDIQYMLTNDSLNYVNYVCDIDDSCAIGLTGPSWKTSLKLA-------------IDSW----TPTV--------FFGPFNPKLSDHDHFPYVHQIATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGVQLHSDLREESQRHGICLAFVNVIPETMKIYMTRGNMYDKQIMTSSAKVVIIYGEMNSTLEISFRRWAYLGARRIWITTSQWDVITNKKD-FSLDLFHGTVTFAHHKGWIAKFKNFMQTMNTSKYPINISQSVLRWNYFNCSVSKNSI-KMDHFTCENPLELTALHNYDMALSDEGYNLYNAVYAVAHTYHEHILQQVESQKMAEDKGEYTECQQLAPLLKTRVFTNPVGEMVNMNHREYQCAEYDIFIIWNFPQGLGLKVKIGSYFPCFPQSQQLHISEDLEWATGGTS----VPSSMCSVTCTPGFRKIHQKETADCCFDCVQCPENEVSNET-DMEQCVRCPDDQYANLEQTHCLQRAVSFLAYEDPLGMALGCMALSFTAITILVLVTFVKYRDTPIVKANNCILSYILLISLVFCFLCSLLFIGHPNQVTCILQQTTFGLFFTVAVSTVLAKTITVVMAFKLTTPGGRMRGMMMMTGAPKLVIPICTLIQLVLCGIWLLTSPPFIDRDIQSEHGKTVIFCNTGSVLAFHVVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCIFVPKCYAILVRPDSNCIQKYKGKLLY------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G5E8Y4-1", "uniprot_id": "G5E8Y4_MOUSE", "id": "G5E8Y4-1", "name": "", "aln": "----------MKKMCALTISFLLLKFSLLLCCLKE--PICFWRIKSSEYNDGDLQSECGYFLWTMKKLMKDDFYNVRLDFR-----------------------------------------------IPASEYEFVLVMFFATDEINKNPDLLPNTSLVFSVMAG--KCQDSLGNLDIQYMLINDSLNYVNYVCDIDDSCAIGLTGPSWKTSLKLA-------------IDSW----TPTV--------FFGPFNPNLSDHDRFPNVHQIATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGIQLHSDLREESQRHGICLAFVNVIPETMKIYMTRGNMYDKQIMTSSAKVVIIYGEMNSTLEISFRRWVYLGARRIWITTSQWDVITNKKD-FSLDLFHGTVTFAHHKGWIAKFKNFMQTMNTSKYPINISQSILRWNYFNCSVSKNSI-KMDHFTCKNPLELTALHNYDMALSDEGYNLYNAVYAVAHTYHEHILHQVESQKMVEDKGKYTECQQLALLLKTRVFTNPVGEMVNMNHREYQCAEYDIFIIWNFPQGLGLKVKIGSYFPCFPWSQQLHISEDLEWATGGTS----VPSSICSVTCTPGFRKIHQKETADCCFDCVQCPENEVSNETVDMEQCVRCPDDKYANLEQMHCLQRAVSFLAYEDPLGMALGCMALSFTAITILVLVTFVKYKDTPIVKANNCILSYILLISLVFCFLCSLLFIGHPNQVTCILQQTTFGLFFTVAVSTVLAKTITVVMAFKLTTPGKRMRG--MMTGAPKLVIPICTLIQLVLCGIWLLTSPPFIERDIQSEHGKTVIFCNKGSVLSFHVVLGYLGSLALGSFIVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCIFVPKCYVILVRPDSNYIQKFKGKLLY------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3UW56-1", "uniprot_id": "G3UW56_MOUSE", "id": "G3UW56-1", "name": "", "aln": "----------MKKMCSLTMSFLFLKFSLILCCLTE--PICFWRIKSSEYNDENLQSECGYFLWTMKKLMKDDFYNVRLDFR-----------------------------------------------MPAREYEFVLVMFFATDEINKNPDLLPNTSLVFSVMAD--KCQDSLGILDLKYMLVNDTLNYVNYVCEADDSCAIGLTGPSWKASLKLA-------------IDTW----APKV--------FFGPFNPNLSDHDRFPNVHQIATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGVQLHSDLREESQRHGICLAFVNVIPETMKIYMTRGNMYDKQIMTSSAKVVIIYGEMNSTLEISFRRWVYLGAQRIWITTSQWDVITNKKD-FSLDLFHGTVTFAHHKGWIAKFKNFMQTMNTSKYPISISESILRWNYLNCSVSKNSI-KMDHFTCKNPLELTALHNYDMALSDEGYNLYNAVYAVAHTYHEHILQQVESQKMVEDKGKYTECQQLAPLLKTRVFTNPVGELVDMNHREYQCAEYDIFIIWNFPQGLGLKVKIGSYFPCFPQSQQLHISEDLEWATGGTS----VPSSMCSVTCTAGFRKIHQKETADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANIEQTHCLQRAVSFLAYEDPLGMALGCMALSFTAITILVLVTFVKYKDTPIVKANNCILSYILLISLVFCFLCSLLFIGHPNQVTCILQQTTFGLFFTVAVSTVLAKTITVVMAFKLTTPGRRMRGMMMMTGAPKLVIPICTLIQLVLCGIWLLTSPPFIERDIQSEHGKTVIFCNTGSVLSFHVVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCIFVPKCYVILVRPDSHFIQKYKGKLHY------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PZX4-1", "uniprot_id": "E9PZX4_MOUSE", "id": "E9PZX4-1", "name": "", "aln": "----------MKKMCVLTTSFLFLKFSLILCCLTE--PICFWRIKDSEYNDGELQSECGFFLWTMEKPMEDDFYNVRFDFR-----------------------------------------------IPASEYEFVLVMFFATDEINKNPDLLPNTSLVFSVIGG--KCQDSLGLLGEEYILINDSLNYVNYVCKADDTCVIDLTGPSWKTSLKLA-------------IDSW----TPKV--------FFGPFNPNLSDHDRFPYVHQVATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGIQLHSDLREESQRHGICLAFVNVIPETMKIYMTRGNMYDKQIMTSSAKVVIIYGEMNSTLEISFRRWVYLGARRIWITTSQWDVITNKKD-FSLDLFHGTVTFAHHKGWIAKFKNFMQTMNTSKYPINISQSVLRWNYFNCSVSKNSI-KMDHFTCKNPLEWTALHNYDMALSDEGYNLYNAVYAVAHAYHEHILHQVESQKMAEDKGKYTECQQLAPLLKTRVFTNPVGELVNMNQREYQCAEYDIFIIWNFPQGLGLKVKIGNYFPCFPRSQQLHISEDLEWVTGGTL----VPSSMCSVTCTPGFRKIHQKETADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANLEQSHCLQRTVSFLAYEDPLGMVLGSMALSSSAITILVLVTFMKYKDTPIVKANNCILSYILLISLVFCFLCSLLFIEHPNQVTCILQQTTFGLFFTVAVSTVLAKTITVVMAFKLTTPGKRMRG--MMTGAPKLVIPICTLIQLVLCGIWLLTSPPFIDRDIQSEHGKTVIFCNKGSVIAFHVVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGKIMVVVEVFSILASSAGLLGCIFVPKCYVILVRPDSNFIQKYKGKLLY------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9Q1C1-1", "uniprot_id": "E9Q1C1_MOUSE", "id": "E9Q1C1-1", "name": "", "aln": "------------MMFTSIFIVLLLKLPLLLCNSAE--NMCFWRVKLNENCDGDLPQDCAFLLYTQVDPAPKDFLKYLFKSC-----------------------------------------------LPSKIHQYLLSLYFAMEEINSNPYLLPNVSLGIEYFKG--KCNGYLSLFTNLNIMTKYYHTFPNYICDPG-ACEIALTGPLWISSAQVAT-----------ILQLK---FIPQVR-----QITYGPFYPLLSDQSKFPNLHQIAPKNRFLPEAIVSLLFHFSWIWVGLVIQDDDQGIQFLLDIKEEMQRNGVCLAFVNVIPQNMHLFTTRAEKYYNQIITSSANVVILYGELNTALEVSFKHWKYLGTQKIWFTTSQWDAITREKD-FSLTSFYGTLTISQYHGDVSTLNNFFQGANLSKDTHYFSSERLGWMYFNCSILKSNCKTPNQCTSSNLLEWLPRHSFDMAMNDESYNIYNAIYAVAHALHEMVLQKIDFQQLENVTQLMQECVQIHAFLENMQFLNPIGDVVIINQQAKTDAEYEIYMIWNFPQGLGVKVKIGRFYSYFLHDQKLYLYEDMIQWASGYS---QIPPSVCSVSCAPGFKKFYLEEKPSCCFDCSPCPENEISNAT-DLTQCVKCPDGQYANIERNHCFPKVVTYLAYADPLGIVLACMALFLSMLSVLVLGIFVKNQYTPIVKANNRTLSYILLISLTLCFLCSLFFIGHPSTARCLLQQITFGILFTVAVSAVLAKTITVLLAFSITIPGRRVKW-LLLFGTHKVIIPICSLFQLIICGFWLGLSPPFVERDTHTEHGHIIIMCNKGSLIAFYSVLGYLGCLALASFIMAFLVRNLPDTFNEAKFLTFSMLVFCSVWVTFLPVHHSTKGKAMVAVEVFSILASSAGLLGCIFIPKCYIIVLRPDRNFIQRSKGKNHS------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "L7N221-1", "uniprot_id": "L7N221_MOUSE", "id": "L7N221-1", "name": "", "aln": "-------------MFTLIFLFLLLNIPLHVADFIH--PRCFWKMKRNENKDRNQGTECTFVIQAVQQPVEKEYFSHILNIQ-----------------------------------------------TQTENRKYALALAFSINEINRNPDLLPNMSLIFKFSAE--NCVWENKLMSLMHSSLQNYDILPNYLCEEYTECVMALTSLNWATTVTLYT-----------ILNNFMSEQFLQIT--------YGPFHPVLSDHEKFPYLHQMASDHTSLALALVSFIIHFGWNWVGLVISDSDQGIQFLSYLRREMEKYTVCFAFVNMIPVNMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPSMKD-FTFGNKYGTFDFQQHNSEISGFKNFVQTLNSVKCPDEY-LVELEWMHFNCEVSASKCKPLKNCSSSYSFDWLMEHTFDMAFIEKSYYIYNAVYAFAHALHQFTFQKFDNLPKDNGKKHNYSCKKVDSSLRKTQFTNPVGDIVNMNQKGELQEEYDIFYIWNFPQGLGLRIKIGMFSPYFPNGQQVHLSEVMIRWAKGST---QVPTSVCSADCGPGSRKFEMDGMAACCFHCKPCPENEISNET-NVDNCVQCPEDQYANTEQNHCIHKAVVFLSYEEPLGMALSLLSLFFSAFTTVILGVIVKHHNTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSVTCFLQQITFGVVFTVALSTVLAKTITVVLAFKITASQRMMKY-FLVSGASNYIILICTLIQVIVCAVWLGASPPFVDIDAQSEHGHIIIVCHKGSVNAFYSILGYLALLSFGSFTLAFLSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKVMVAVEIFSTLASSAGILGCIFVSKCYTILFRPDRNSVEMTRVKSSFHAHIS-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "K7N674-1", "uniprot_id": "K7N674_MOUSE", "id": "K7N674-1", "name": "", "aln": "-------------MFTLIFLFLLLNIPLLVADFIH--PRCFWKMKRNENKDRNQGTGCTFVIHAVQQPVEKEYFSHILNIQ-----------------------------------------------TQTENRKYALALAFSINEINRNPDLLPNMSLIFKFSAH--NCVWESEIMNLMLLSLQNYDIFPNYLCKEYTKCAMALTNLNWATTVTLYT-----------ILNNIISEQFLQIT--------YGPFHPVLSDHEKFPYLHQMASDHTSLALALVSFIIHFGWNWVGLVISDSDQGIQFLSYLRREMEKYTVCFAFVNMIPVNMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPRMKD-FTFGNKYGTFDFQQHNSEISGFKNFVQTLNSVKYPDDY-LVELEWMHFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFIEKSYYIYNAVYAFAHALHQFTFQKFDNLPKDNGKEHNYSCKKVDPSLRKMQFTNPVGDIVNMNQRDKLQEEYDIFYIWNFPQGLGLRVKIGMFSPYLPNGQQVHLSEVIIKWTKGST---QVPTSVCSADCGPGSRKFGMDGMAACCFHCKPCPENEISNET-NVDNCAQCPEDQYANTEQNHCIHKAVVFLNYEEPLGMALSLFSLCFSAFTTVILGVIVKHHNTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSVTCILQQITFGVVFTVALSTVLAKTIVVVLAFKITASQRMMKY-FLVSGASNYIILICTLIQVIVCAVWLGASPPSVDIDAQSEHGHIIIVCHKGSVNAFYSILGYLALLSFGSFTLAFLSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKVMVAVEIFSTLASSAGMLGCIFVSKCYTILFRPDRNSVEMTRVKSSFHARVS-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9Q6I0-1", "uniprot_id": "V2116_MOUSE", "id": "E9Q6I0-1", "name": "Vomeronasal type-2 receptor 116", "aln": "-------------MFTLIFLFLFLNIPLLVADFIS--PRCFWKMKQNEYRDRHHGTGCIFLILAIQQPVKKEYFSHILNIQ-----------------------------------------------THTENHKYALALAFSIYEINRNPDLLPNMSLIFIFSAD--SCEWESELS-LIRFGLQNSDNLPNYLCEELTKCILALTNMNWATTVTLHT-----------ILSNFLSDQLLHIT--------YGTFHPALSDHEKFPYLHQMASDHTSLALALVSFIIHFGWNWVGLVISDSDQGIQFLSYLRREMEKYTLCFAFVNMIPLNINLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPSMKD-FTFGNKYGTFAFEQHHSEISGFKHFVQTLNSVKCPDEY-LVKLEWMHFNCEVSASKCKTLKNCSSNHSLKWLMVHTFDMAFIEESYYIYNAVYAFAHVLHQFTFQKFDNLPKDNGKEHNYSCKKLYSYLRKNHFINPVGDRVSMNQRDKLQEEYDIVYIWNFPQGLGLRVKIGMFSPYFPNGQQVHLSEDMLKWARGST---QVPTSMCSADCGPGSRKFRMDGMAACCFHCKPCPENEISNET-NVDNCVQCPEDQYANTEQNHCIRKAVVFLSYEEPLGVALSLLSLCFSAFTTVVLGIFVKHHNTPIVKANNRTLTYLLLISLIFCFLCPLLFIGHPNSATCILQQLTFGVVFTVSLSTVLAKTITVVLAFKIIASQRMMKY-FLISGAINYIIPICILIQVIVCAVWLRASPPSVDIDAHSEHGQIIIVCHKGSVNAFYCVLGYLAILAFGSFTLAFLSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKVMVAVEIFSTLASSAGMLGCIFVPKCYTILFRQDQNSLEMIRVKSSSNVHVS-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9Q0E7-1", "uniprot_id": "E9Q0E7_MOUSE", "id": "E9Q0E7-1", "name": "", "aln": "-------------MFTLIFLFWLLNIPLLLADFIS--PRCFWKMKQNENRDRNQGTGCTFMIHAVQRPVEKEYFSHILNIQ-----------------------------------------------THTENHKYALALAFSIYEINMNPDILPNMSLIFEFSVH--NCVWESKLMSFMHVSLQNYDIFPNYLCKEYTKCAMALTSLNWATTVKFNT-----------ILNNFISQQFFQIT--------YGPFHPVLSDHEKFPYLHQMASDHTSLAFGLVSFIIHFGWNWVGLVISDNDQGIQFLSYLKTEMEKNTICFAFVNMIPMSMNLYMSKAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWNVSPGMKD-FTFGNEYGTFAFGQHHSEISGFKHFVQTLNSVKCPDEY-LVKLEWMHFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFIEGSYDIYNAVYAFAHALHQITFQKFDNLPKDNGKEHNYSCKKLYSFLRKTQFINPVGDRVNMNQRDKLQEEYDIFYIWNFPHGLGFKVKIGIFSPYFPNGQQVHLSEDMIEWAKGSA---QMPTSVCSADCGPGSRKFRMDGMAACCFHCKPCPENEISNET-NVDYCVQCLEDQYANTEQNHCIRKIVVFLSYEEPLGVALSLISLFFSAFTIVVLGVIVKHHSTPVVKANNRTLTYILLISLIFCFLCPLLFIGHPNAATCILQQITFGIVFTVSVSTVLAKTITVVLAFKIIASQRMMKY-FLVSGAINYIIPVCILIQVIVCAVWLGASPPSVDIDGQSEHGQIIIVCHKGSVNAFYCVLGYLATLAIGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKVMVAVEIFSTLASSAGMLGCIFVPKCYTILFRPDQNSLEMIRVKSSSNARSS-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PZA6-1", "uniprot_id": "E9PZA6_MOUSE", "id": "E9PZA6-1", "name": "", "aln": "-------------MFTLILLFLLLNIPLIVADFID--PRCFWRIKQNKDEDGNLGSGCSFFIQAVQWPVEKEYFSSILNTQ-----------------------------------------------THTENHKYALVLAFSINEVNRNSDLLPNMSLIFTFSAL--ICDYESQLKSLIHLSLQNHEIFPNYICNDD-VCAVALTGLNWTTTLTLYT-----------ILNNFISHQFLHLT--------YGPFHPVLSDHEEFPYLYQMASEDTSLALAMVSFIIHFSWNWVGLAISDNDKGIQFLSYLRREMEKNTVCFAFVSMIPVNMHLYMTRTEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLDIKRIWVTTSQWAITTGKKD-FTFNNLYGTFAFGHHHGEISGFKNFVQTLNLLKYSDEY-LVKLEWMYFNCEVSAPKCKTLKNCSSNHPLEWLMVRTFDMAFTEGSYAIYNAVYAVAHALHELTFQKFDNLPTDNVKEQNYACNKLGSFLRKIHFTNPVEDRVNMNQRNKLQENYDIFYVWNFPQGLGLKVKIGIFSPYIINGQQLHLSEDMLEWARGST---QMLTSVCSADCGPGFRKFGKNGMPACCFDCSPCPENEISNET-NVELCVPCPEDQYANTEQNHCIHKALIFLTYKDPLGMALSLMALCFSAFTAVVLLVFVKHHSTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSVTCILQQVTFGVAFTVAVSTVLAKTITILLAFRVTAPQRMMKY-FLVSGTYIYIIPICTLIQVIVCAVWLGAAPPSVDIDARSEHGHIIIVCNKGSVSAFYCVLGYLACLAFGSFTLAFLSRNLPSTFNEAKSITFSMLVFCSVWVTFLPVYHSTKGKVMVAVEIFSTLASGAGMLICIFVPKCYIILFMPDRNSLQMIRKKSSSHAHLS-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A140T8U3-1", "uniprot_id": "A0A140T8U3_MOUSE", "id": "A0A140T8U3-1", "name": "", "aln": "-------------MFTLILLFLLLNIPLIVADFIY--SRCFWRIKQNKDKDGNLGSGCALFIQAVQWPVEKEYFSPILNTQ-----------------------------------------------TYTENYKYILVFMFSINEVNRNSDLLPNMSLIFTFSAL--SCN-ESQLKSFIHLSLQDHDYFPNYICNDY-ICGVALVGLKWETTLTLYT-----------ILNNFMSHQFLFLN--------YGPFHPAMSDHEEFPYIYQMASEDTSLALAMVSFIIHFSWNWVGLAISDNDEGIQFLSHLRREMEKNTVCFAFVSMIPVNMHLYMTRTEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLDIKRIWVTTSQWDIITSKKD-FTFNNLYGTFAFGHHHGEISGFKNFVQTLDLLKFSDEY-LVKLEWMYFNCEDSAPKCKTLKNCSSNHPLEWLMVRTFDMAFTEGSYAIYNAVYAVAHALHELTFQKFDNLRPDNVKGQKYACNKLGSFLRKIHFTNPVGDRVNMNQRNKLQENYDIFYVWNFPQGLRLKVKIGIFSPYFINGQQLHLSEDMLEWARGST---QMLTSVCSADCGPGFRKFRRNGMPACCFDCRPCPENEISNET-NVELCVPCPEDQYANTEQNNCIQRAVIFLTYKDPLGMALSLMALCFSAFTAVVLLVFVKHHSTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSVTCVLQQVTFGVAFTVAVPTVLAKTITIVLAFRVTAPQRMMKY-FLVSGASIYIIPICTLIQVIVCAVWLGAAPPSVDIDARSEHGHIIIVCNKGSVSAFYCVLGYLACLAFGSFTLAFLSRNLPSTFNEAKSITFSMLVFCSVWVTFLPVYHSTKGKVMVAVEIFSTLASGAGMLICIFVPKCYIILFMPDRNSLQMIRKKSSSHAHLS-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "K7N789-1", "uniprot_id": "K7N789_MOUSE", "id": "K7N789-1", "name": "", "aln": "------------MMFSWIFILWLLQISKFVSAFILNISRCYYIITEEFHHEGDVVIGAFFPLHTYYTGKKMPHPTVPYLYLDN------------------------------------------YIQYNFKNYQYILTLLFAIEEINRNPNLLPNISLGFDFYNVRFTEKETLDNAVIWLSALVQRKFLPNYNCKKR-NFTAALTGTTWKTSAQIGT-----------LLQLFK---FPQIT--------FGPYDPLLNDHSQYSSLYQMAPKDTSLSLAIVSLMVHFRWSWVGLILPDDHKGNKILSDFREEMERKGICIAFVKMIPETWNLYFAKFWEN-----MDETNVIIIYGDSDTLEGLMRNIGQRLFTWKVWIMNIEYNVFDRADY-FMLDSFHGSLIFKHNYRENFEFTKFIQTVNPNKYPEDIYLPKLWHLFFKCSFADISCHALDNCQTNASLDLLPSHIFGVAMNEESTNIYNGVYALAHSLHEMRLQQLQMQPYLNGEGMVFFPWQLNTFLKDIEVRNNR----SLDWRQTIHAEYNILNLWNLPKGLGLKVKIGSFSANAPQGQQLFLSEQMIQWPEIFS---EIPQSACSESCGPGFRKVTLEGKAICCYKCTPCADNEISNES-DVDQCVKCPEGHYANTEKNNCLEKSVSFLAYEDPLGMALASIALCLSALTIFVIGIFVKHRDTPIVKANNRTLSYILLITLTFCFLCSLNFIGQPNTAACILQQTTFAVAFTVALATVLAKTITVVLAFKVSFPGRMIRW-LMISRGPNYIIPICTLIQLLLCGIWMATSPPFIDQDAHSEYGHIIILCNKGSAVAFHSVLGYLCFLALVSYTMAFLSRNLPDTFNESKFLSFSMLVFFCVWVTFLPVYHSTKGKVMVAMEVFCILASSTALFAFIFGPKCYIILLRPEKNSFRHTRKKTHIPVPKL-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8V5L1A2-1", "uniprot_id": "A0A8V5L1A2_MOUSE", "id": "A0A8V5L1A2-1", "name": "Parathyroid cell calcium-sensing receptor", "aln": "--------------MWLCAFIFAFFVCLSGSDLSGPRAWILPRQSPHFDRPGDVIVGGSFSIFHFSDGTPSDFTAPPTGLQTS--------------------------------------------SVSMWGYRVAQSFVFAIEEINRSAHLLPNLTLGFSIRNS--GDSVHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFSQVS----------------------YSSSLPSLSDKIQFPSFLRTLTSDITSSHAVTQLIIHFQWSWVIILAQDDDFGQQASSLATQQLSPAGVCIEYHLHVPS--HQSLGKIEETVQKMQKCTSKVVLVFLSNSNFQLILHGLLGVPVSGQVWVSKGTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHNMLACEHQERK--GTNSHNFHSWQLLHALKKVHFKTLDGIKIMFDANGDLVTKFDIFQGQKTPAGVFHLVHVGMIDPQVSSGNKMMVQLKEDLQV---------PSSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQR-DMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFKVTRPRSRIQI-CLSPGTSTLVVLIASLIQVVLCGVWLATFPPFPDKDMLSEPQHIVIQCHDGSGATFFCVLGYLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYYSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPSWLKQGHHI------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A3B2W422-1", "uniprot_id": "A0A3B2W422_MOUSE", "id": "A0A3B2W422-1", "name": "Parathyroid cell calcium-sensing receptor", "aln": "--------------MWLCAFIFAFFVCLSGSDLSGPRAWILPRQSPHFDRPGDVIVGGSFSIFHFSDGTPSDFTAPPTGLQTS--------------------------------------------SASMWGYRVTQSFVFAIEEINRSAHLLPNLTLGFSIRNS--GDSVHGALYETMGFLTGQKEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVS----------------------YSSSLPSLSDKIQFPSFLRTLTSDITSSHAVTQLIIHFQWSWVIILAQDDDFGQQASSLATQQLSPAGVCIEYHLHVPS--YQSLGKIEETVQKMQKCTAKVVLVFLSNLNFQLILRGLLGVPVSGQVWVSKGTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHNMLACEHQERK--GTNSHNFHSWQLLHALKKVHFKTLDGIKIMFDANGDLVTKFDIFQGQKTPAGVFHLVHVGMIDPQVSSGNKMMVQLKEDLQVSSLNAEETVPTSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFTDQR-DMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFVLALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFRVTRPRSRIQI-CLSPGTSTFVVLIASLIQVVLCGVWLATSPPFPDKDMISEPQHIVIQCQEGSGATFFCVLGYLGFLAGGTFSVAFLARGLPDIFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLKQGYCAQQEKQGEMLQRRYKFSGESPEPNI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A3B2W4A7-1", "uniprot_id": "A0A3B2W4A7_MOUSE", "id": "A0A3B2W4A7-1", "name": "Parathyroid cell calcium-sensing receptor", "aln": "--------------MWLCTLLSVLFGCLSGSALSGPRVWIIPRQSPRFDRPGDVIVGGSFSIFHFSDGTLSNFTAPPPVLKTS--------------------------------------------SASMWSYRVAQSFVFAIEEINRSAHLLPNLTLGFSIRNS--GDSVHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVS----------------------YSSSLPSLSDKIQFPSFIRTLTSDLTCSHAVTQLVIHFQWSWVIILAHDDDFGQQASSLATQMLTPAGVCIEYHLHVPS--HQSFGKIEETVQKMQKCTARVVLVFLSNSNFQLILHGLLAVPVSGQVWVSMDTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSRIDAAYTAVYSIAHALHNMLACEHQERK--GTNSHNFHSWQLLHNLRNVYFKTSDGNKIMFDANGDLVTQFDIFQGKKTPAGVFHLVHVGLIDPQASSGNKMMVQLKQDLQVSSLNAEITVPTSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFTDQR-DMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTIFAVVFTVAVSSVLAKTLTVVLAFRVTRPRSRIQV-CLSSGASTSVVLIASLIQVVLCGIWLITSPPFPDRDMISEPRHTVIQCHEGSGANFFCVLGFLGFLAGGTFSVAFLARGLPDVFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLRQGHQVQHNRQCEMLQRRCVSSGESLGSSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A3B2WBA1-1", "uniprot_id": "A0A3B2WBA1_MOUSE", "id": "A0A3B2WBA1-1", "name": "Parathyroid cell calcium-sensing receptor", "aln": "MGLSCHWLSDPLAGMWLCTLLPVLFGCPSGSALSGARAWLLPRQSPHFDRPGDVIVGGSFSIFRFSNGTLSNFTAPPAGLQTS--------------------------------------------SVSMWGYRVAQSFVFAIEEINRSTHLLPNLTLGFSIRNS--GDSAHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVS----------------------YSSSLPSLSDKIQFPSFIRTLTSDLTSSHAVTQLIIHFQWSWVIILAHDDDFGQQASSLASQVLTPAGVCIEFYLYVPS--HQSLGKIEETVRKMQKCTARVVLVFLSNYNFQLILYGLLAVPVSGQVWVSKDTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCMWPYQNITVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHDMISYEHQDGK--GTNSQDFQPWQLLHVLRKVHFKTPDGSEIMFDANGDLVTKFDIFQGQKTPDGVFHLVCVGLIDPQASSGNKMMVQKKMLKYQMK---HAQVPTSVCSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQR-DMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFKVTRPRSRIQI-CLSPGTSTLVVLIASLIQVVLCGVWLATFPPFPDKDMLSEPQHIVIQCHDGSGATFFCVLGYLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYYSARGKSTVAVEIFSILASTAGLLGGIFIPKCCIILLKPEKNTSSWLRQGHHV------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GK53-1", "uniprot_id": "A0A8I6GK53_RAT", "id": "A0A8I6GK53-1", "name": "", "aln": "--------------MWLCTFLFVLLGCLPGSALSEPRSWILPRQSPHFDRPGDVMVGGSFSIFCFSDGTLSNFTAPPTGLQAS--------------------------------------------RVSMWGYRVAQSFVFAIEEINKSTQLLPNLTLGFSIQNS--GDSVHGALYETMGFLTGQEEPIPNYTCCHGSPQAALVGDTRSSLSLPMARLLGLYKFSQIS----------------------YSSSLPSLSDKIQFPSFLRTLPSDLTSCHAVTQLIIRFQWSWLIILSQDDDFGEQASSLATQQLSAAGVCIEFHLDVPS--QHSLGKIEETVQKMQKCTARVVLVFLSNSNFQLILSGLLAASVSGQVWVSNDTLHIAMALSIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLHPSQIPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQVCSGNESLKNKPYPFPEVSKIDAAYTAVYSIAHALHDMVACEHQDGI--DTNPQDFHPWQLLHVLKKVHFRTPDGSEIMFDANGDLVTKFDILQGQKTLNGVFHLVHVGMIDPQASSGNIMMIQLKEDLQVSSMNAEITVPTSICSERCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQR-DMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALMAILLAGLALLVLGVFLKHRDTPVVRVNNRTLSYFLLISLSLCSLCSLLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTVTVVLAFRVTKSGSRIQV-CLSPGASTSVVLIASLIQVVLCGVWLATSPPFPERDMISEPQHIVIQCQEGSGATFFCVLGFLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLRQGHCAHQDRQCSLFH--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9PAH3-1", "uniprot_id": "A0A8M9PAH3_DANRE", "id": "A0A8M9PAH3-1", "name": "", "aln": "----------MTKKSELLLLMVLVTHGICVPNLAQVCRLLGQPALPLLSEERNINIGAIFSLHKSALLKSHNFTSKPKQTTCG--------------------------------------------GLNLREFKFVQTLIFAIEEIN-NSSLLPGASLGYKIYDS--CGSVAQAIFSGMALMNGYEETLSDTSCSTPPAVHAIVGESNSSPTIGLASVVGPFSLPLVS----------------------HFATCSCLSNRKRFRTFFRTIPSDYYQSRALAQLVKHFGWTWVGTVRSRSDYGNNGIATFEEAAKQEGICIEYSEAVFK--TDPEVQFLKTIEVIKKATTKVVVAFMAFGDFVLLLKVMAQQNITGIQWIGSESWITSRNLAETKEYHFLSGAVGFAIANSKPVGLREFLMNVHPDKELNNELLKEFWETVFLCSFRNSSSGGCTGSEKLS---ELQNEYTDFSELRIENKVYTAVYAVAHSLHNVLKGFKFFTN--SSKKQLPTPQKVLEYLRDVNFTVNTNENIFFDASGDPVARYDLVNWQPTKDGSLQFKLVGIYDSSLPSEQRLQINQESMLWAGN---SGQLPVSVCSESCPPGTRKAVQKGRPICCYDCIPCAEGEISNYT-DSSDCFPCGLEYWSNESKDRCVLKVIEFLSYTEIMGVGLCIFSFIGVLLTATVSFLFYFYKETPIVRANNSELSFLLLFSLTLCFLCSLTFIGRPTDWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFRATLPGSNVMK-WFGPLQQRLSVVSLTLIQVIICVLWLTMSPPFPFLNLSYYREKIILECNLGSAFGFWAVLGYTGLLSTLCFVLAFFARKLPDNFNEAKFITFSMLIFCAVWLTFIPAYVSAPGKYTVAVQLFAILASSFGLLFCIFAPKCYIILLKPEKNTKKQMMGKS--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : . : *: *:* .. :**. :* : * . : . . . . : :: . : .. .: :: :* * *: .. : :*: : : : :.* : : : *. *:. : : .*. : : * . . *..:*: ** *: :: :. . : ::: * :* : : : * ** * .* : . **:.* *.:. .:: : * * ::. : .*. : :* : : *. * :: : : : . **:*:.** :: :**::* :* **.* *: * *.*:: *.: *.:.:. **.**:.:::** . : : : *.*:... .*: ** : : :: *: ** * :**: *: : :**: * **. ***:* ::****:: .** :*:* : *: * *.:::*. *** .:. ** .** :: ", "identical_positions": 102, "similar_positions": 175, "identity": "10.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100723-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "L7N2A0-1", "uniprot_id": "L7N2A0_MOUSE", "id": "L7N2A0-1", "name": "", "aln": "-----------MKKLRVFTFSLLLLKCFLISCH----LTEPICFWRLKNNE---DNDGDLRSDCGVFLAAVEGPIDQ-IYN-----ISDF-----------------------------------------------RIPARRYEFFLVMFFATDEINKNPYLLPNMSLISPVDHGQCEETLGLLDEIYLEKNNSVEFT-DYICVFYGTCYIGLIGPSWKTSVKLS---------IHSR----TPRVRMCETRLVFFGPFNPNLSDHDQFPYVHQVAIKDTHLSHGMASLMLHFRWTWIGLVISDDDQSIQFLSDLREEMQRHGICLAFVNMIPEDMQLYMTRAKIYDEEIMTSTAKVVIIYGEMNSTLQVSFRRWEDLGVRRIWITTSQWDVIT-NKNDFSLDFFHGTVTFAHHVGKIAKFRNFLQTMNSDKYPVNISKSILGWNYFNCSV---SKKGN-KKDHFTFNNTLEWTALHNFDIVLSEEGYNLYNAVYAVAHTYHELILQQVESQQTAVPKGIFTDCQQVSSMLKSRIFTNPVGELVNMKHRENQCADYDIFIIWNFPQGLGLKVKIGNYLPCYPWSQQLHISEN-LEWATGGSS---VPSSMCSVTCTAGFRKIHQKQTADCCFDCDQCPENEVSNETADMEQCVRCPDDKYANLEKTQCLQRVVSFLAYEDPLGMTLGCMALTFSALTVLVLVIFVKYKDTPIVKANNRIVSYILLISLVFCFLCSLLFIGHPTQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGGRMRG-MLASGAPNLVIPICTLIQLVLCGIWLVTSPPFIDRDIQSEHGKTIIICNKGSVIAFHFVLGYLGALALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCVILLRPDLTFLQKYKDKLPS------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "L7N217-1", "uniprot_id": "L7N217_MOUSE", "id": "L7N217-1", "name": "", "aln": "-----------MKKLCVFILFFMLLKFSLISHH----LTEPICFWRIKNNE---DNDGDLRSDCGFFLAAVEGPIDQ-IYN-----ISNF-----------------------------------------------RIPARRYEFFLVLFFATDEINKNPYLLPNMSLISPIASGQCEKTLENLDKIYSEKNHTVQFT-DNICVFYETCYISLIGPSWKTSVKLS---------IHHG----TPRV--------FFGPFNPKLSNHDLFPNVHQVATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQCIQFLSDLREEMQGHGICLAFVNMIPEDMQLYMTRAEIYDKQIMESTAKVVIIYGEMNSTLEVSFRRWEDKGVRRIWIATLQWDVIT-NKKDFTLDFFQGTVTFAHHVGDIANFRNFLQTMNNEKYPINISESILQWNSFNCSF---SKNSN-KKDHFTFNNTLEWTALHIYNMVLSEEGYNLYNAVYAVAHTYHELILQQVESQQTEVPKGTFTDCQQVSSMLKSRIFTNPFGELVNMKHQESQCADYDIFIIWNFPKGLGLKVKIGYYLPCYQRSQQLHIYD--LEWATGGTL---VPSSMCSVACTAGFRKIHRKQTADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPLGMALGCMALFLSALMVLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCPLLFIGHPNLATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRG-MLASGAPNLVIPICTLIQLVLCGIWLVTSPPFIDRDTQSEYGKTIIICNKGSVIAFHFVLGYLGALALGSFTVAFLARNLPDRFNEAKFLTFSMLVYCSVWITFLPVYHSTRGAVMVVVEVFSILASSAGLLGCIFLPKCCVILLD---------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "K7N621-1", "uniprot_id": "K7N621_MOUSE", "id": "K7N621-1", "name": "", "aln": "-----------MKNLCVFTLSFFLLEFSLILCH----LTEPICFWRINNNE---DNDGDLRSDCGFFLAAVEGPTDD-SYN-----ISDL-----------------------------------------------RIPARRYEFFLVMFFATDEINKNPYLLPNMSLIFPINHGQCEKTLGDLDKIYSEKNYTVEFT-DYICVSFGTCFIALIGPSWKTSIKLS---------INSG----TPRV--------FFGPFNPKLSDHDQFPYVHQVATKDTRLSHAMVSLMFHFTWIWIGMVISDDDQSIQFLSDMREEMQRHGICLAFVNMIPEDMQLYMTRATIYDKQIMESTAKVVMIYGEMNSTLEVSFRRWEDLSIRRIWITTSQWDVIT-NKNDFSLDFFQGTVTFAHHVGEIANFRNFLQTMNSEKYTVNISESRLGWNYFNCSI---SKNSN-KKDHFTFNNTLEWTTLHKYDMVLSEEGYNLYNAVYAVAHTYHELVLQQVESQQMTVPKGTFTDCQQVSSMLKSRIFTNPVGELVNMKHRENQCTEYDIFIIWNFPQGLGLKVKIGSYLPCFQQSQQLHISED-LEWATGGSS---VPPSLCSVTCTAGFRKIHQKQTADCCFDCDQCPENAVSNETVDMEQCMRCPDDKYANLEKTHCLQRAVSFLAYEDPLGMALGCTALSFSALTVLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRG-MLASGAPNIVIPICTLIQLVLCGIWLVTSPPFIDRDMQSEHGKTIIICNKGSVIAFHFVLGYLGALALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTQGTVMVVVEVFSILASSAGLLGCIFLPKCCVLLRIQNSNFLHKYKHELHS------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "L7N1X2-1", "uniprot_id": "L7N1X2_MOUSE", "id": "L7N1X2-1", "name": "", "aln": "-----------MKELCVFILCFLLLKFSLILCH----LTEPICFWRIKSNE---DNDGDLRSDCGFFLAAVEGPIDQ-IYN-----ISDF-----------------------------------------------RIPARRYEFFLVLFFATDEINKNPYLLPNMSLISPITSGQCEKTLGDLDKIYSEKNITVEFT-DNICVFYGACYISFIGPSWKTSVKLS---------IHTG----TPRV--------FFGPFNPKLSDHDQFPYVHQVATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGIQFLSDMREEMQRDGICLAFVNMIPGNMQLYMTRAKIYDKQIMESTAKVVIIYGEMNSTLEVGFRRWIHLGVRKIWITTSQWDVVT-NKKDFSFNFFHGTVTFAHHIGELVKFRNFLQTMNNEKYPVNISETRLGWNSFNCSI---SKNSN-KKDHFTFNNTLEWTARNNFDMVLSEEGYNLYNAVYAVAHTYHELILQQVESQQMAVPKGIFTDCQQVASLLKTRVFTNPVGELVNMKHRENQCADYDIFIIWNFPKGLGLKVKIGSYLPCFHQSQQLHISED-LEWATGGTS---VPSSMCSVTCTAGFRKIHQKQTADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANVEKTHCLQRVVSFLAYEDPLGMALGCMALSFSALTVLILVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQITFGVFFTVAISTVLAKTITVVLAFKLTTPGRRMRG-MLASGAPNLAIPICTLIQLVLSGIWLVKSPPFIDRDTQSEHGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCVILD----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9Q759-1", "uniprot_id": "E9Q759_MOUSE", "id": "E9Q759-1", "name": "", "aln": "-----------MKNLRGFGLSFMLLKFSLIWCH----LTEPICFWRIKNNE---DNDGDLRSDCGFFLAAVEGPIDH-TYN-----ISDF-----------------------------------------------RIPARRHEFFLVLFFATDEINKNPYLLPNMSLIFPEDPGQCEKLLGELDKIHSEAKFTVDFT-DYICAGYGTCYIGLIGPSWKTSVKLS---------TNSG----TPRV--------FFGPFNPKLSDHDQFPYVHQVATKDTHLSHGMITLMLHFRWTWIGLVISDDDQGIQFLSDLREEMQRHGICLAFVNMIPEDMQLYMTRAKIYDKQIMESTAKVVIIYGEMNSTLEVSFRRWEDLGARRIWITTSQWDVIT-NKNDFSLDFFHGTVTFEYHHSEIAKFKNFMKTMNTDKYPVNISESILRWNYFNCST---SMNSYSKMGHFTFNNTLEWTALHNFDMALSEEGYNLYNAVYAVAHTYHELILLQVESQQTEEPKGTFTDCQQVSSTLKSRIFTNPVGELVNMKHRENQCADYDIFIIWNFPQGLGLKVKIGSYLPCFPQSQQLHISED-LDWATGGSS---VPSSLCSVTCTAGFRKIHQKQTADCCFDCDQCPENAVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPLGMALGCMALTFSALTVLVLVTFVKYKDTPIVKANNRILSNILLISLVFCFLCPLLFIGHPNKATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTSPGGKMRG-MLASGAPNLVIPICTLVQLVLCGIWLVTSPPFIDRDTQSEHGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFVPKCFVILVRPDSNFLQKYKDKLFY------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "L7N472-1", "uniprot_id": "L7N472_MOUSE", "id": "L7N472-1", "name": "", "aln": "-----------MKKLRTFTISFLLLKFSLILCH----VTDPICFWRIKNNE---ENDGDLRSDCNFLLWTDYESTEFNFYN-----IVDF-----------------------------------------------RIPARRYEYFLVLFFATDEINKNPDLLPNMSLIVWLLSGQCGDEWSVLHKNYSQENINVKFI-NYDCLSP-ACYIDLTGPSWKTSLKMS---------IQSR----TPKV--------FFGPFNPDLRDHDQFPFVHQVATKDTYLSHAMVSLMHHFRWMWIGLVISDDDQGIQFLSDLREEMQRHGICLAFVNMIPENMQIYMTRATIYDKQIMESTAKVVIIYGEMNSTLEVSFRRWEDLGVRRIWITTSQWDVIT-NKNDFSLDFFHGTVTFEHHHSEIAKFKNFMKTMNTDKYPVNISQSIVGWNYFNCST---SMNSFSKMDHLTFNNTLEWTALHNFDMVLSEEGYNLYNAVYAVAHTYHELILLQVESQQTEVPKGIFTDCQQVASMLKSRIFTNPIGELVNMKHRENQCADYDIFIIWNFPQGLGLKVKIGSYLHCFSQSQQLHISED-LEWATGGTS---VPSSLCSVTCTAGFRKIHQNETADCCFDCDQCPENEVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPWGMALGCMALFLSALTVLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRG-MLASGAPNLVIPICTLIQLFLCGIWLVTSPPFIDRETQSEYGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCVILVRLDSNFLQKYKDKLPS------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "K7N6Z8-1", "uniprot_id": "K7N6Z8_MOUSE", "id": "K7N6Z8-1", "name": "", "aln": "-----------MKKLRTFTISFWLLKFSLIFCH----VTEPICFWRIKNNE---ENDGDLRSDCNFFLWTYDESTEINFYN-----IVDF-----------------------------------------------RIPARRYEFFLVLFFATDEINKNPDLLPNMSLIVWLLGGQCGDEWSVLYKNYSQENINVEFI-NYDCLSP-DCYIHLTGPSWKTSLKMS---------IQSR----TPKL--------FFGPFNPNLSDHDQFPYVHQVATKDTHLSHAMVSLMLHFRWAWIGLVISDDDQGIQFLSDLREEMQRHGICLAFVNMIPKDMQIYMTRATIHDKQIMESTAKVVIIYGEMNSTLEVSFRRWEDLGARRIWITTSQWDVIT-NKNDFSLDFFHGTVTFEHHHSEIAKFKNFMKTMNTDKYPVNISQSIGGWNYFNCST---SMNSYSKMDHLTFNNTSEWTALHNFDIVLSEEGYNLYNAVYAVAHTYHELILLQVESQQTEVRKGIFNDCQQVSSMLKSRIFTNPVGELVNMKHRENQCAEYDIFIIWNFPQGLGLKVKIGSYLPCFQQSQQLHISED-LDWATEGTS---VPSSMCSVTCTAGFRKIHQNETADCCFDCDRCPENEVSNETADMEQCVSCTGDKYANLEKTHCLQRAVSFLAYEDPLGMSLGCIALFLSALTSLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRG-MLASGAPNLVIPICTLIQLVFCGIWLVTSPPFIDRDTQSEYGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCAILVRLDSNFLQKYKDKLPS------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9Q4X4-1", "uniprot_id": "E9Q4X4_MOUSE", "id": "E9Q4X4-1", "name": "", "aln": "-----------MKKLRTFTISFWLLKFSLILCH----VTEPICFWRIKNNK---DNDGDLRSDCNYFLWTFEETTEINFYN-----IVDF-----------------------------------------------RIPTRRYEFFLVLFFATDEINKNPDLLPNISLIFWLFGGQCEDEWGVLDTNYSQNNINVKFI-NYDCLSP-NCYIDLTGPSWKTSLKLPNILTIIVLMWMSHPLFYILQV--------FFGSFNPNLSDHDQFPYVHQVATKDTLLSHAMVSLMLHFRWTWIGMVISDDDQGIQFLSDLREEMQRHGICLAFVNMIPENMQIYMTRAKIYDKQIMESTAKVAIIYGEMNSSLEVSFRRWEDLGVRRIWITTSQWDVIT-NKNDFSLDFFHGTVTFEHHHSEIAKFKNFMQTINTDKYPVNISESILGWNYFNCST---SMNSYSKMDHLTFNNTSEWTALHKYDMALSEEGYNLYNAVYAVAHTYHELILLQVESQQMAVPKGTFTDCQQVSSMLKSRIFTNPVGELVNMKHRENQCADYDIFIIWNFSQGLGLKVKIGSYLHCYPRSQQLHISED-LEWVTGGSS---VPSSMCSMTCTAGFRKIHQNETADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPLGIALGCMALFLSALTVLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRG-MLASGAPNLVIPICTLIQLVFCGIWLVTSPPFIDRDTQSEYGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCVILVRLDSNFLQKYEHKLPS------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GKI6-1", "uniprot_id": "A0A8I6GKI6_RAT", "id": "A0A8I6GKI6-1", "name": "", "aln": "-----------MKKMCAFTISSLLLKFSLILCS----FTEPSCFWRIQNNE---DNDGDLRSDCGFVLITYEGPIEENFYNN----VINF-----------------------------------------------RIPARRYEVFLVLLFATDEINRNPYLLPNMSFMFSRIVGMCEDTLGSLERKYTPQSNSWKFI-NYNCGIQEVCDVQLTGPSWTTSLKLA---------INSR----NPKV--------FFGPFNPNLSDHDQFPYVYQVATEDTCLSHAMVSLMLHFRWTWIGLVITDDDQGIQLLTDLREEMERHGMCLAFVNMIPETMQIYMTKAKIYDNQIMTSSAKVVIIYGEMNSTLEVSFRRWAYLAAQRIWITTSQWDVIT-TRKDFSLDFFHGTFTFAHHNVELPKFRHFMQTMNTSKYPVDISQSMLGWNYFNCSI---SKNSISKIDHFTLNNTLEWLAQHKFDMFLSEEGYNLYNAVYAVAHTYHELILQ-VESQKMAEPKGLFTDCQQVALLLKTRAFTTPVGELVNMNHRENQCAKYDISIAWNFPQGLGLKVKIGSYFPCFPQSQQLHISED-LEWATGGTL---IPTSMCSVACIAGFRKIHQKQVTHCCFDCAHCPENEVSNETADMEQCVRCPDDKYANLEQTYCLQRVVSFLAYEDPLGMALGCTALCFSTLTVLILFTFLKYKDTPIVKANNCLLSYILLISLIFCFLCSLLFIGHPNHITCILQQTTFGVFFTVAISTVLAKTITVVMAFKISTPGNRMKG-MLTSGAPNLVIPICTLIQLVLCGIWLGTSPPFIDRDIQSEPGKTIVICNKGSIFAFHFTLGYLDSLTLMSFAVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTKGKVMVVVEVFSILASSAGLLGCIFVPKCYVILVRTDSNFLQKYKDKFHY------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A3B2WCY4-1", "uniprot_id": "A0A3B2WCY4_MOUSE", "id": "A0A3B2WCY4-1", "name": "", "aln": "-----------MKKLHAFTISFSLLKFSLILYS----LTEPNCFWRIQSNE---DNDGDLRSDCGFVLFTYEGPIEEKFYNN----VIHFSGTMNNLDLIWNAQQSRNGGHTCDPDLEDGRSSLLIWMLKNSGHEKHRIPARRYEFLLVMYFATDEINRNPYLLPNMSLIFSLIVGMCEDTLGYIEEKYSPQKNRLNFI-NYNCGIPQTCNIQITGPSWTTSLKLA---------INSR----RPKV--------FFGPFNPNLSDHDQFPYVHQVSTKDTHLSHAMVSLMLHFKWTWIGLVISDDEQGIQFLSGLREEMQTYAICLAFVNMIPETMQIYMTRADIYDKQIIESTAKVVIIYGEMNSTLEVSFRRWGYLGARRIWITTSQWDVIT-NEKDFSLDFFHGTITFAHHNGRIAKFNNFLQTMNTSKYPIDVTQTMQDWNYFNCSI---FKNSVRKTGQFIFNNTLEWTTQHKIDMVLSEEGHNLYNAVYAVAHTYHELILQQVESQKMPKLKGVFSDCHQVASLLKTRVFTNPVGELVNMKHRENQCADYDIFNIWNFPQGLGLKVKIGSYFPCFPQSQQLCISEN-MEWATGGAL---VPTSMCSVTCAAGFRKIHQKHTADCCFDCVLCPENEVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPLGMALGSMTMCFSALTVLVLVTFVKYKDTPIVKANNRILSYILLISLILCFLCSLFFIGQPNHATCILQQTTFGVFFTVAISTVLAKTITVVMAFKLTTPGRRMRG-MLASGTPNLVIPICSLVQLVLCGIWLVTSPPFIDRDTQSEHGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFVPKCFVILVRPDSNFLQKYKDKLFY------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PYF5-1", "uniprot_id": "E9PYF5_MOUSE", "id": "E9PYF5-1", "name": "", "aln": "-----------MKKLCVFTISFLLMTFSLFLCS----LTGPSCFWRIQNNE---DNDGDLHRDCGFFLFTSEEPIKEDFYHF----CIDF-----------------------------------------------RIPARRYEVFLVMFFATDEINRNPYLLPNMSLIFCLIVGMCGDTLGYLEETHSP-NNTWNSI-NYNCEIRPICDIELTGPSWTTSVKLA---------INSR----KPKV--------FFGPFNSHLSDHDQFPYIYQVATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQSIQFLSDLREAMQRHGICLAFVNMIPENMQIYMTRGKIYDKQIMTSSAKVVIIYGEMNSTLEVSFRRWAYLCARRIWITTSQWDVIT-NKRDFSFDFFHGTVTFAHHNGEIVIFRNFLQTVNTSKYPLDISQTMQEWNYFNCSI---SKNSNSKMDHFTFNNTLEWTALQKLNMVLSEEGYNLYNAVYAVAHTYHELILQQVEFQKMAEPKGIFTDCQQVASLLKTRVFTNPVGELVNMKHRENQCADYDIFNIWNFPQGLGLRVKIGSYYPCFPQNQQLHISED-LEWATGGTS---VPTSMCSVTCTAGFRKIHQKQTADCCFDCAHCPENEVSNETADMEQCVRCPDDKYANLEQTHCLQRAVSFLAYEDPLGMALGCMALCFSALTLLVFFTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVVMAFKLTAPGRRVRG-MLVAGAPNLAIPICTLIQIVLCGIWLVTSPPFIGRDTKSEHGKTILICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLMFCSVWITFLPVYHSTRGKAMVVVEVFSILASSAALLGFIFVPKCYVILVKSDSNFREKYKNKFHY------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LNQ1-1", "uniprot_id": "F1LNQ1_RAT", "id": "F1LNQ1-1", "name": "", "aln": "-----------MKELCTFTISFLLLKFSFIMWG----LTEPSCFWRIKNNG---DNDGDLRTDCGFVLFTRQEPIEENFYNE----IVYF-----------------------------------------------RIPARSYEFFLVMFFATDEINKNPYLLPNMSLIFSLIVGMCEDTLEYVDTNYSFKRNTLNIV-NYNCYLRARCYIQLTGPSWKTSLKLT---------INSR----KPKV--------FFGPFNPNLSDRDQFPYVNQIARKDTFLSHAMISLMLFFEWTWIGLAISDDDQGIQFLSVTREVMQKHSICSAFVNVIPENMQIYMARANIYDKQIMTSSAKVVIIYGERNSTLEVSFRRWEYLGAQKIWITTSQWDVIT-NKRVFSLDFFHGTVTFAYHNGRIPKFRNFMQTMNTSKYPVDISQTILEWNYFNCSI---FKNSDSEMNHFTSKNTEEWLAQHKFDMVLSEEGYNLYNAVYAVAHTYHELILQEVESQKILRHKGRFINCQQVASLLKTRIFMNPVGELVNMNQRENQCAEYDIFNIWNFPQGLGLKVKIGSYFSCFPQSQQLQISED-LKWATGGTS---VPTSMCSVTCTAGFRKIHQNEAAHCCFDCALCPENEVSNDT-DMEQCVRCPDDKYANLEQTYCIQRHVSFLAYEEPLGLTLGCMALCFSALTILVLVTFVKHKNIPVVKANNCILSYILLISLIFCFLCSLLFIGHPKKTTCILQQITFGIFFTMAISTVLAKTITVVMAFKLTTPGRRMRR-ILASGAPNLIIPICTLIQLVICGTWLATSPPFIDRDIQSEHGKVIIICNKGSVTAFHFVLGYLRSLALGSFAVAFLARNLPDRFNETKFLTFSMLVFCSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCVFIPKCYVILVRPNSNFLQKYKNKLLY------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LAY5-1", "uniprot_id": "A0ABK0LAY5_RAT", "id": "A0ABK0LAY5-1", "name": "G-protein coupled receptors family 3 profile domain-containing protein", "aln": "-----------MKKLCAFTIAIFSLKFCLILCS----LTEPNCFWRIKSSE---DNDGDLRSDCGFVLFTHEGPIPEDFYN----DIINF-----------------------------------------------RIPARKYEFFLVLLFATDEINKNPYLLPNMSLIFNIIFGLCEDTLGVLDKAYLHQNSNSELF-NYYCGINQLCDVDLTGPSWTTSLKLS---------IYSR----TP--------KIFFGSFNPNLSDHDQFPYIYQIAAKDTYLFHGMVSLMFHFGWTWIGLVISDDDQGIQFLSDLREEMQRHAICLAFVNMIPETMQIYKTRVKIYDQQLMTSSAKVVIIYGEVNSTLELSFRRWAYLGAQRIWITTSQWDVIT-HKKDFSLDFSHGTVTFAHHHNDIAVFRNFMQTINTSMYPVDISQSMLQWNHFNCSI---SKN-KKKMDCFTFKNPLEWLIQHTFDMVLSEEGYNLYNAVYAVAHTYHKLIFQQVESQKMEEPKGLFTDCQQVTSLLKTIEFTNPVGELVDTKHKENQCATYDIFITWNFPQGLGLKVKIGSYFPCLPQSQQLHISED-WEWVTGETL---IPPSVCSMTCTAGFRKIHQKETADCCFDCVQCQENEIANDTADMEQCVKCPDDSYANLEQSQCLQRVVTFLAYEDPLGMALGCMALSFSAITILVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLYIGHPNQATCILQQTTFAIFFTVAISTVLAKTITVVTAFKLTTPERRIKK-IMIKGAINLLIPICTLIQLVLCAVWLVISPPFIDRDIQSEHGKVIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKDMVIVEVFSILASSAGLLGCIFFQKCYVLLVRPDLNVLRK-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LKX1-1", "uniprot_id": "A0ABK0LKX1_RAT", "id": "A0ABK0LKX1-1", "name": "", "aln": "-----------MKKMWAFTIAFFSLKFCLILCS----LTEPSCFWRIKRSE---DNDGDLRSDCGFVLFTLESPIEENFYT----RIINF-----------------------------------------------RIPARKYEFFLVLFFAIDEINKNPYLLSNMSLIFSIIVGLCEDTMGVLDKAYSHQSKIFKRI-NYFCGIKQRCDINLTGPSWTTSLKLS---------IYSR----TP--------KIFFGSFNPNLSDHDQFPYIYQRANKDTYLFCGMVSLMFHFGWTWIGLVISNDDQGIQFLSDLREEMQRHAICLAFVIMIPETMQIYKTRVKIYDQQLMTSSAKVVVIYGEMNSTLELSFRRWAYLGAQRIWITTSQWDVIT-NQKDFSLDFSHGTVTFAHHHNDITIFRNFMQTINTSKYPIDISQSMLQWNHFNCSI---SKN-KKKMDCFTFNNPLEWLVQHTFDMVLSEEGYNLYNAVYAVAHTYHELIFQQAESQKMADPKGVFTDCQQVASLLKTRVFINPVGELVNMNHKENYCAKYDIFIIWYFPQGLGLKVKIGSYFPCLPQSQQLHISED-WEWVTEETL---VPSSVCSVTCTAGFRKIHQKQTADCCFDCVQCQENEIANDT-DMEHCVRCPEDSYANLEQTECLQRVVTFLAYEDPLGMALGCMALSFSAITILVLVTFVKYRDTPIVKANNRILSYILLISLAFCFLCSLLFIGHPNQATCILQQTTFAIFFTVAISTVLAKTITVVTAFKLTTPGRRIRK-MMIKGAINLLIPICTLIQLVLCAIWLVTSPPFIDRDIQSEHGKIIIICNKGSVIAFHIVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCIFVQKCYVLLVQPDLNVLQK-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6GL30-1", "uniprot_id": "A0A8I6GL30_RAT", "id": "A0A8I6GL30-1", "name": "", "aln": "-----------MKKLCAFTIAFFPLKFCLILCS----LTEPNCFWRIKKIE---VYDGDLQNDCGFVLFTLESPIEENFYN----HIINF-----------------------------------------------RIPARKYEFFLVMFFATDEINKNPYLLSNMSLIFSFIFGMCEDTMGVLDKAYLHQNNYFDLL-NYNCGRKKRCDVKLTGPSWKTSLKLS---------VNSR----AP--------KIFFGPFNPNLSDHDQFPYIYQIATKDTYLLHGMVSLMFHFEWTWIGLVITDDDQGIQFHSDLREEMQRHAICLAFVIMIPESIKLYNTKFKIYDQQLMTSSAKVTIIYGKMISTLGLSFRRWAYLVARRIWITTSKLDDIT-YDKDFSLDFFHGTVIFVHHHNDIATFRNFMQTINTSKYPVDISQSMGQWNHFNCSI---SKN-KKKMDFFMLKNPLEWLKQHTFDMVLSEEGYNLYNAVYAVAHTYHELIFQQVESQEMAKPKGLFTDCQKVASLLKTRVFTNPVGELVNMNHKENQCAKYDIFIIWNFPKGLGLKVKIGSYFPCLQQSQHLHISED-WEWVTGETL---VPSSVCSETCTAGFRKSHQKQTADCCFDCVQCQENEIANDT-DMEQCVRCPDDSYANLEQTECLQRVVTFLAYEDPLGMALGCMALSFSAITILVLVTFVKYRDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQATFAIFFTVAISTVLAKTITVVTAFKLTTPGRRIRK-MMIKGATNLLIPICTLIQLVLCAIWLVTSPPFIDRDIQSEHGKVIIICNKGSVTAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMVIVEVFSILASSAGLLGCIFVQKCYVLLVRPDLNVLQK-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LDN1-1", "uniprot_id": "A0ABK0LDN1_RAT", "id": "A0ABK0LDN1-1", "name": "", "aln": "-----------MKKLCAFTIAFFPLKFCLILCS----LTEPNCFWRIKKIE---VYDGDLQNDCGFVLFTLESPIEENFYN----HIINF-----------------------------------------------RIPARKYEFFLVMFFATDEINKNPYLLSNMSLIFSFIFGMCEDTMGVLDKAYLHQNNYFDLL-NYNCGRKKRCDVKLTGPSWKTSLKLS---------VNSR----AP--------KIFFGPFNPNLSDHDQFPYIYQIATKDTYLLHGMVSLMFHFEWTWIGLIITDDDQGIQFHSDLREEMQRHAICLAFVIMIPESIKLYNTKFKIYDQQLMTSSAKVTIIYGKMISTLELNFARWTYLVARRIWITTSKLDVIT-YDKDFSLDFFHGTVIFAHHHNDIATFRNFMQIINTSKYPVDISQSMGQWNHFNCSI---SKN-KKKMDFFMLKNPMEWLTQHTFDMVLSEEGYNLYNAVYAVAHTYHELIFQQVESQEMAKPKGLFTDCQQVASLLKTRVFTNPVGELVNMNHKENQCAKYDIFIIWNFPNGLGLKVKIGSYFPCLQQSQHLHISED-WEWVTGETL---VPSSVCSETCTAGFRKSHQKQTANCCFDCVQCQENEIANDT-DMEQCVRCPDDSYANLEQTQCLQRAVTFLAYEDPLGMALGCMALSFSAITVLVLVTFVKYRDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQATFAIFFTVAISTVLAKTITVVTAFKLTTPGRRIRK-MMIKVATHLLIPICTLIQLVLCAIWLVTSPPFIDRDIQSEHGKVIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMVIVEVFSILASSAGLLGCIFVQKCYVLLVRPDLNVLQK-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AK91-1", "uniprot_id": "A0A8I6AK91_RAT", "id": "A0A8I6AK91-1", "name": "G-protein coupled receptors family 3 profile domain-containing protein", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLSLMFHFGWTWIGLVISDDDQGIQFLSDLREEMQRHAICLAFVNMIPETMQTYKTRVKIYDQQIMTSSAKVVVIYGEMNSTLELSFRRWAYLGAQRIWITTSQWDVIT-HKKDFSLDFFHGTVTFAHHHNDIPVFRNFLQTINTSKYPIDISQSMLQWNHFNCSI---SKS-NNKMDCFTFNNPLEWLAQHTFDMVLSEEGYNLYNAVYAVAHTYHELILQQIESPKMEEPKGVFTDCQQEVSLLKTRVFINPVGELVNMNHKENQCAKYDIFINWNFPQGLGLKVKIGSYFSCLPQSQQLHISED-WEWVTRETL---VPSSVCSVTCIAGFRKIHQKQTANCCFDCVQCQENEIANDT-DMEQCVRCPDDSYANLEQTKCLQRAVTFLAYEDPLGMALGCMALSFSAITILVLVTFVKYRDTPIVKANNRILSYILLISLAFCFLCSLLFIGHPNQATCILQQTTFAIFFTVAISTVLAKTITVVTAFKLTTPGRRIRK-MMIKGATNLLIPICTLIQLVLCAIWLVTSPPFIDRDIQSEHGKVIIICNKGSVTAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTKGKVMVVVEVFSILASSAGLLGCIFVQKCYVLLVRPDLNVLRK-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZQ04-1", "uniprot_id": "D3ZQ04_RAT", "id": "D3ZQ04-1", "name": "", "aln": "-----------MKKLCAFTVAFLFLKFSVILCRT--QLTEPNCFWRIKNSE---DNDGDLQNDCGFILFTFKGRIEENFYNKLL-NFINF-----------------------------------------------RIPARKYEFFLVMFFATDEINKNPYLLSNMSLLFSIIFGMCEDTLGIVDEVYSQSNKGLAFT-NFICGVESTCDIQLTGPFWTTSLKLA---------IYSK----AP--------KLFFGPFNPNLNDHVQFPYVHQVASKDTCLSHGMASLMLHFKWTWIGLAISDDDQGIQFLSDLKEEMQRHGICLAFVNMIPENMQIYMTMAKIYDKQIMTSSAKVVVIYGKINSTLEVSFRRWGNLGAHRIWITTSQWDVIT-NIKDFNLDFFHGTVTFAHHHSDIAEFRNFMQTINTSKYPVDISQSMLGWNHFNCSI---SKN-NSKIDYFTFNNPLEWLAQHTFDMVLSEEGYNLYNAVYAVAHTYHELILQQVESQKMEEPKGVFTDCQQVASLLKTRVFTNPLGELVNMNHRENQCIEHDIFIIWNFPQGLGLKVKIGTYFPYFTHNQQLHISED-LEWATGGTL---VPSSMCSMTCTAGFRKIHQKETADCCFDCVQCPENEVSNDTADMEQCVRCPDDSYTNLEQTQCLQRTVSFLAYEDPLGMALGCMALSFSAITILVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQDTCILQQTTFGVFFTVAISTVLAKTITVVTAFKLTTPGRMIRR-RMIKVATNFLIPICTLIQLALCGIWLGTSPPFIDRDIQSEHGKVIIICNKGSIIAFYFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMIVVEVFSILASSAGLLGCIFVPKCYVLLVRPDLNVLQKKDELLYQ------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0M8M8-1", "uniprot_id": "A0ABK0M8M8_RAT", "id": "A0ABK0M8M8-1", "name": "", "aln": "-----------MKKLCAFPITFLILKFSLIYFH----LTEPSCFWRIKNSE---ETDGDLRSDCGFVLLAFEEPIEENYYN----ELINF-----------------------------------------------RIPATKYEFFLVMFFATDEINKNPDLLPNMSLIFNLVGRMCEDTLGLLDEIYSQENKTSYII-NYVCGIELSCDIDLIGPSRTTSLKLA---------IHSM----MP--------KVFFGPFNSNLIDHDQFPYIYQIAIKDTCLPHGMVSLMLQFGWTWVGLIISDNDQGIQFFSDLREEMQRHGICLAFVNVIPETMQRYSTRAKIYDKQLMTSSAKVVIIYGEMNSTLEVSFRRWAYLGVQRIWVTNSQWDVII-NKRDFSLDFFHGTVTFAHHHSGMTIFRNVMQTMNTSKYPIDLSQSMLGWNYFNCSI---SENRHSKTDHFTFNNTLEWLALHKFDMVLSEEGYNLYNAVYAVAHTYHELISQNVESQKVAEPKGLFTDCQQVASLLKATVFTNPVGELVNMNHRENQCAEYDIFIIWNFPEGLGLKVKIASYFPCFPHNQQLHTSED-LEWATEGTL---VPSSMCSATCTAGFRKIHQKQTADCCFDCVQCPENEVSNETADMEQCARCPDDKYANSEQTYCLQRTVSFLAYEDPLGMALGCMALFFSAITILVLVTFVKYKDTPIVKANNCILSYILLISLIFCFLCSLLFIGHPNKATCILQQTTFGVFFTVAVSAVLAKTVTVVMAFKLTTPGRRMRG-MLASGATNLVIPICTLIQLVLYGIWLAISPPFIDRDIQSEHGKTIIICNKGSVIAFHFVLGYLGSLALGSITVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCIFVPKCYVILVRPDLNFLQK-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3ZXT3-1", "uniprot_id": "D3ZXT3_RAT", "id": "D3ZXT3-1", "name": "", "aln": "-----------MKKLCAFTVSFLFLKFSLILCS----FTELSCFWRMKNSE---DSDGDLRSDCGFVLLTTKKNIED-FYN----DINEV-----------------------------------------------RIPARRYEFFLVMFFATDEINNNPYLLPNISLIFSIIAGLCEDTLGVLDEIYSQQNNSWNIV-NYICEKGQRCDIELTGPSWKASVKLS---------IHSM----IPSVRMCDTGCVFFGPFNPNLSDHDQFPYMYQIATKDTCLSHGMVSLILHFRWNWLGLVISDDDQGIQFLSDLREEMQSHGICLAFVNMIPETMQVYMIKAKIYDKQIMTSSAKVVIIYGEMNSTLEVSFRRWSYLGVQRIWITTSQWDVIT-IKKDFNLDFFHGTLTFAHHKVEVAKFRNFMQTRNPAKYPVKFFESVLGWNYFNCSI---SKN-SNLMDHFIFNNTLEWIALNKYDMVLSEEGYNLYNAVYAVAHTYHELILQQTESQNIAEPNGVFIDCQQVASLLKTRVFTNPVGELVNMKHREKQCVEYDIFITWNFPEGLGLKVKIGSYFPCFPQSQQLHISED-LEWATGGTS---VPSSMCSATCTAGFRKIHQKQTADCCFDCVQCPENEVSNETADMEQCVRCPDDMYANLEQTQCLQRTVSFLAYDDPLGIALGCMALSFSAITILVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVVMAFKLTTPGRRLRG-MMITWASNFVIPFCTLIQLVLCGIWLVTSPPFIDRDIQSEHGKTIIICNKGSVIAFHVVLGYLGSLALGSFTIAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMVVVEVFSILASSADLLGCIFVQKCYIILVSSNSNFLHK-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A3Q4EIC8-1", "uniprot_id": "A0A3Q4EIC8_MOUSE", "id": "A0A3Q4EIC8-1", "name": "", "aln": "-----------MKKLCAFTISLLFLKFSLILCC----WSEPSCFWRIKNSD---DNDGDLQRECHFYLGAADTPVEDNFYSSLLK---------------------------------------------------FRIAASEYEFLLVMFFAIDEINRNPYLLPNITLMFSFIGGNCQDLLRVMDQAYTQINGHMNFV-NYFCYLDDSCAIGLTGPSWKTSLKLA---------MHSS----MPLV--------FFGPFNPNLRDHDRLPHVHQVAPKDTHLSHGMVSLMFHFRWTWIGMVISDDDQGIQFLSDLREESQRHGICLAFVNMIPENMQIYMTRATIYDQQIMTSSAKVVIIYGEMNSTLEVSFRRWEELGARRIWITTSQWDVIT-NKKDFTLNLFHGTITFAHHRVEIPKLNKFMQTMNTAKYPVDISHTILEWNYFNCSI---SKN-SIRMHHITFNNTLEWTSLHNYDMAMSDEGYSLYNAVYAVAHTYHEYIFQQVESQKKAKPKRYFTACQQVSSLMKTRVFMNPVGELVNMKHRENQCTEYDIFIIWNFPQGLGLKVKIGSYLPCFPQRQKLHISDD-LEWAKGGTSPQ-VPSSVCSVACTAGFRKIYQKETADCCFDCVQCPENEISNET-DMEQCVRCPDDKYANIEQTHCLSRAVSFLAYEDPLGMALGCMALSFSAITILVLVTFVKHNDTPIVKANNRILSYILLISLVFCFLCSLLFIGPPDQVTCILQQTTFGVFFTVSVSTVLAKTITVVMAFKLTTPGRRMRG-MMMTGAPKLVIPICTLIQLVLCGIWLVTSPPFIDRDIQSEHGKIVILCNKGSVIAFHVVLGYLGSLALGSFTLAFLARNLPDTFNEAKFLTFSMLVFCSVWITFLPVYHSTRGRVMVVVEVFSILASSAGLLMCIFVPKCYVILIRPDSNIIKKHKGKVLN------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2BE32-1", "uniprot_id": "A2BE32_MOUSE", "id": "A2BE32-1", "name": "", "aln": "-----------MKKLCAFTISFLFLKFSLILCC----LSEPSCFWRIRNSE---DSDGDLQRECHFYLWLIDESIEDNFVSDLN----------------------------------------------------FRIAASEYELLLVIFFATDEINKNSYLLPNMTLMFSIIGGNCHDLLRSLDQEYTEIKGHMNFV-NYFCYLDDSCAIGFTGPSWKTSLKLG---------LHSS----MPLV--------FFGPFNPNLRDHDRLPHVHQVATKDTHLSHGMVSLMFHFRWTWIGLVISDDDQGIQFLSDLREESQRHEICLAFVNMIPENMQIYMTRATIYDKQIMTSSANVVIIYGEMNSTLEVSFRRWEELGAWRIWITTSQWDVIK-NKKEFTFNLFHGTITFAHHKVEIPKFKKFMQTMNTAKYPVDISHTILEWNYFNCSI---SKN-SSKMDHMTFNNTLEWTALHNYDMAMSDEGYNLYNAVYAAAHTYHEHILQQVESQKKAKPKRYFTACQQVSSLMKTRVFSNPVGELVNMKHRENQCTEYDIFIIWNFPQGLGLKVKIGSYIPCFPKSQQLHICDD-LEWAMGGT----VPSSVCSVACTAGFRKIHQEETADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANIEQTHCLSRAVSFLAYEDPLGMALGCMALSFSAITILVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQVSCILQQTIFGVFFTVSVSTVLAKTITVVMAFKLTTPGRRIRG-MMMTGAPKLVIPICTLIQLVLCGIWLVTSPPFIDRDIQSEHGKTVILCNKGSVIAFHVVLGYLGSLALGSFTLAFLARNLPDTFNEAKFLTFSMLVFCSVWITFLPVYHSTRGRVMVVVEVFSILASSAGLLMCIFVPKCYVILIRPDSNFIKKHKGKLLN------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "K7N5U4-1", "uniprot_id": "K7N5U4_MOUSE", "id": "K7N5U4-1", "name": "", "aln": "-----------MKQLCAFTISFLLLKFSLILCC----LTEPICFWRIKNSE---DDDRDLQRECHFYLWAIDKPIEDDFYNIVYN---------------------------------------------------FRIAASEYEILLIMFFATDEINKNPYLLPNITLIFTIIGGHCHDLLGGLDEAYTQINGRVKFV-NYFCYSDDSCLIGLTGPSWKTSLKLA---------MDSS----MPMV--------FFGPFNPNLCDHDRLPHVHQVAPKDSHLSHGMVSLMFHFTWTWIGLVISDDNQGIQFLSDLRKEMQRHGICLAFVNMIPENMQIYMTRATIYDKQIMTSSAKVVIIYGDMNSTLEISFRRWEDLGAQRIWITTSQWDVIT-NKKDFTLNLFHGTVTFAHYKGEIPKFRNFMQTINTDKYPVDISHTILEWNYFNCSS---SKN-SSKMDHFTFNNTLEWTALHKYDMALSEEGYNLYNAVYAAAHTYHEHFLQQAESQKRADPKRDFTECQQVSSLLKTRVFTNPVGELVNMMHGENECTEYDIFIIWNFPQGLGLKVKIGSYLPCFPQSQQLHISDD-LEWAMGGTS---VPSSMCSMTCTAGFRKIHQKETADCCFNCVPCPENEVSNETADMEQCVMCPDDKYANIEQTHCLQRTVSFLAYEDPLGMALGCMALSFSAITTLVLVTFVKYKDTPIVKANNRILSYILLISLDFCFLCSLLFIGHPTQVTCILQQTTFGVFFTVAVSTVLAKTITVVMAFKLTTPGRRMRG-MMMTGAPKLVIPICTLIQLVLCGIWLVTSPPFIDRDIKSEHGKTVILCNKGSVIAFHFVLGYLGFLALGSFTVAFLARNLPDRFNEAKFLTFSMLMFCSVWITFLPVYHSTRGKVMVAVEVFSILASCAGLVGCIFFPKCYVILIRSDSIFIQKYKDELHY------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3YWE3-1", "uniprot_id": "D3YWE3_MOUSE", "id": "D3YWE3-1", "name": "", "aln": "-----------MKKMCALTISFLLLKFSLILCC----LKEPICFWRIKSSE---YNDGNLQSECGYFVWTMKKLMKDDFYNVWLD---------------------------------------------------FRIPASEYEFVLVMFFATNEINKNPDLLPNTSLVFSVMAGNCQDSLGNLDIQYMLTNDSLNYV-NYVCDIDDSCAIGLTGPSWKTSLKLA---------IDSW----TPTV--------FFGPFNPKLSDHDHFPYVHQIATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGVQLHSDLREESQRHGICLAFVNVIPETMKIYMTRGNMYDKQIMTSSAKVVIIYGEMNSTLEISFRRWAYLGARRIWITTSQWDVIT-NKKDFSLDLFHGTVTFAHHKGWIAKFKNFMQTMNTSKYPINISQSVLRWNYFNCSV---SKN-SIKMDHFTCENPLELTALHNYDMALSDEGYNLYNAVYAVAHTYHEHILQQVESQKMAEDKGEYTECQQLAPLLKTRVFTNPVGEMVNMNHREYQCAEYDIFIIWNFPQGLGLKVKIGSYFPCFPQSQQLHISED-LEWATGGTS---VPSSMCSVTCTPGFRKIHQKETADCCFDCVQCPENEVSNET-DMEQCVRCPDDQYANLEQTHCLQRAVSFLAYEDPLGMALGCMALSFTAITILVLVTFVKYRDTPIVKANNCILSYILLISLVFCFLCSLLFIGHPNQVTCILQQTTFGLFFTVAVSTVLAKTITVVMAFKLTTPGGRMRGMMMMTGAPKLVIPICTLIQLVLCGIWLLTSPPFIDRDIQSEHGKTVIFCNTGSVLAFHVVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCIFVPKCYAILVRPDSNCIQKYKGKLLY------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G5E8Y4-1", "uniprot_id": "G5E8Y4_MOUSE", "id": "G5E8Y4-1", "name": "", "aln": "-----------MKKMCALTISFLLLKFSLLLCC----LKEPICFWRIKSSE---YNDGDLQSECGYFLWTMKKLMKDDFYNVRLD---------------------------------------------------FRIPASEYEFVLVMFFATDEINKNPDLLPNTSLVFSVMAGKCQDSLGNLDIQYMLINDSLNYV-NYVCDIDDSCAIGLTGPSWKTSLKLA---------IDSW----TPTV--------FFGPFNPNLSDHDRFPNVHQIATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGIQLHSDLREESQRHGICLAFVNVIPETMKIYMTRGNMYDKQIMTSSAKVVIIYGEMNSTLEISFRRWVYLGARRIWITTSQWDVIT-NKKDFSLDLFHGTVTFAHHKGWIAKFKNFMQTMNTSKYPINISQSILRWNYFNCSV---SKN-SIKMDHFTCKNPLELTALHNYDMALSDEGYNLYNAVYAVAHTYHEHILHQVESQKMVEDKGKYTECQQLALLLKTRVFTNPVGEMVNMNHREYQCAEYDIFIIWNFPQGLGLKVKIGSYFPCFPWSQQLHISED-LEWATGGTS---VPSSICSVTCTPGFRKIHQKETADCCFDCVQCPENEVSNETVDMEQCVRCPDDKYANLEQMHCLQRAVSFLAYEDPLGMALGCMALSFTAITILVLVTFVKYKDTPIVKANNCILSYILLISLVFCFLCSLLFIGHPNQVTCILQQTTFGLFFTVAVSTVLAKTITVVMAFKLTTPGKRMRG--MMTGAPKLVIPICTLIQLVLCGIWLLTSPPFIERDIQSEHGKTVIFCNKGSVLSFHVVLGYLGSLALGSFIVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCIFVPKCYVILVRPDSNYIQKFKGKLLY------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3UW56-1", "uniprot_id": "G3UW56_MOUSE", "id": "G3UW56-1", "name": "", "aln": "-----------MKKMCSLTMSFLFLKFSLILCC----LTEPICFWRIKSSE---YNDENLQSECGYFLWTMKKLMKDDFYNVRLD---------------------------------------------------FRMPAREYEFVLVMFFATDEINKNPDLLPNTSLVFSVMADKCQDSLGILDLKYMLVNDTLNYV-NYVCEADDSCAIGLTGPSWKASLKLA---------IDTW----APKV--------FFGPFNPNLSDHDRFPNVHQIATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGVQLHSDLREESQRHGICLAFVNVIPETMKIYMTRGNMYDKQIMTSSAKVVIIYGEMNSTLEISFRRWVYLGAQRIWITTSQWDVIT-NKKDFSLDLFHGTVTFAHHKGWIAKFKNFMQTMNTSKYPISISESILRWNYLNCSV---SKN-SIKMDHFTCKNPLELTALHNYDMALSDEGYNLYNAVYAVAHTYHEHILQQVESQKMVEDKGKYTECQQLAPLLKTRVFTNPVGELVDMNHREYQCAEYDIFIIWNFPQGLGLKVKIGSYFPCFPQSQQLHISED-LEWATGGTS---VPSSMCSVTCTAGFRKIHQKETADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANIEQTHCLQRAVSFLAYEDPLGMALGCMALSFTAITILVLVTFVKYKDTPIVKANNCILSYILLISLVFCFLCSLLFIGHPNQVTCILQQTTFGLFFTVAVSTVLAKTITVVMAFKLTTPGRRMRGMMMMTGAPKLVIPICTLIQLVLCGIWLLTSPPFIERDIQSEHGKTVIFCNTGSVLSFHVVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCIFVPKCYVILVRPDSHFIQKYKGKLHY------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PZX4-1", "uniprot_id": "E9PZX4_MOUSE", "id": "E9PZX4-1", "name": "", "aln": "-----------MKKMCVLTTSFLFLKFSLILCC----LTEPICFWRIKDSE---YNDGELQSECGFFLWTMEKPMEDDFYNVRFD---------------------------------------------------FRIPASEYEFVLVMFFATDEINKNPDLLPNTSLVFSVIGGKCQDSLGLLGEEYILINDSLNYV-NYVCKADDTCVIDLTGPSWKTSLKLA---------IDSW----TPKV--------FFGPFNPNLSDHDRFPYVHQVATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGIQLHSDLREESQRHGICLAFVNVIPETMKIYMTRGNMYDKQIMTSSAKVVIIYGEMNSTLEISFRRWVYLGARRIWITTSQWDVIT-NKKDFSLDLFHGTVTFAHHKGWIAKFKNFMQTMNTSKYPINISQSVLRWNYFNCSV---SKN-SIKMDHFTCKNPLEWTALHNYDMALSDEGYNLYNAVYAVAHAYHEHILHQVESQKMAEDKGKYTECQQLAPLLKTRVFTNPVGELVNMNQREYQCAEYDIFIIWNFPQGLGLKVKIGNYFPCFPRSQQLHISED-LEWVTGGTL---VPSSMCSVTCTPGFRKIHQKETADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANLEQSHCLQRTVSFLAYEDPLGMVLGSMALSSSAITILVLVTFMKYKDTPIVKANNCILSYILLISLVFCFLCSLLFIEHPNQVTCILQQTTFGLFFTVAVSTVLAKTITVVMAFKLTTPGKRMRG--MMTGAPKLVIPICTLIQLVLCGIWLLTSPPFIDRDIQSEHGKTVIFCNKGSVIAFHVVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGKIMVVVEVFSILASSAGLLGCIFVPKCYVILVRPDSNFIQKYKGKLLY------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M0L6-1", "uniprot_id": "A0ABK0M0L6_RAT", "id": "A0ABK0M0L6-1", "name": "G-protein coupled receptors family 3 profile domain-containing protein", "aln": "--------MADMEKAYTLIVFFLLLRLSFILCS----FPEASCFWRINHNE---HLESNMRKDCGFILFTIPVHLVEDYFR----VLLDF-----------------------------------------------PLPVNTYPYVLVMLFAIEEINKNPNLLPNSTLGFTFLGDQCDITSTNLNNLNMLSKSGEIIP-NYICEYS-DCDVALTGPTWTVSARVAT-------LLQLF---KIPQVML----NVTYGPFHDSLSDHDLFPHLYQIAPKDTSLVLAMVSLMIHFIWKWVGLVILDDDQGVQFLSDMKEEMKINEICLAFVNMIPANMQLYIERAETYYFQIMTSSAKVVIIYGNVNSTLEVSFRRWEMLGIWRLWITTSQWDVIS-RSRDFTIDSFHGTLSLSHHYREISTFKHFIQKTNFSAYPEAVSLVRLGWIYFNCSV---SVSECKTLNHCLSNTILELLPWHSFDMAMNDERYNIYNAVYAVAHAFHNMHLQEVDIKVWESWEGLIPRCMQVNHFLKNVRFINPIGDPVNINQGRNLDAMYDILNVLHFPQGYVLKVKVGQLSPYFAHDQQLFLSEDMIEWATGSRQ---FSTSVCSMPCYPGFKKSHQEGKADCCFDCSRCPANEISNTT-DSEECVKCPEDWYANTEQTHCLPKAVTFLAYEDPLGMALVCLALCFSVLTALVLGVFLKHRETPIVKANNRTLSYILLTALIFCFLCSLLFVGNPNTTTCILQQTTFGILFTVSVSTVLAKTLTVVLAFRITVPGRRMRG-LMVSRISKYIIPICTVVQIILYGIWLWTSPPFVDIDTHSEHGCITITCSKGSVTAFYCVLGYLGSLALVSFTVAFLARNLPDTFNEAKFLTFSMLVFCSVWITFLPVYHSSKGKVMVAVEVFSILASSMGLLGCIFIPKCYIILLRPDRNSIQKFRDKTHS------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LQR9-1", "uniprot_id": "A0ABK0LQR9_RAT", "id": "A0ABK0LQR9-1", "name": "", "aln": "--------MADMEKAYTLIVFFLLLRLSFILCG----FPEATCFWRINHNE---HLESNMRKDCGFILFTIPVHLVEDHFR----VLLDF-----------------------------------------------PLPVNTYPYVLVMLFAIEEINRNPNLLPNSTLGFTVLGDQCDITSTNLNNLNMLSKSGEIIP-NYICEYS-DCDVALTGPTWTVSARVAT-------LLQLF---KIPQVML----NVTYGPFYDSLSDRDLFPHLYQIAPKDTSLVLAMVSLMIHFLWKWVGLVILDDDQGVQFLSDMKEEMKINDICLAFVNRIPANMQLYIERAGIYYFQIMTSSANVVIIYGNVNSTLEVSFRRWEMLGIWRLWITTSQWDVIS-RSRDFTIDSFHGTLSLSHHYREISTFKHFIQKTNFSAYPEAVSLVRLGWIYFNCSV---SVSECKTLNHCLSNTILELLLWHSFDMAMNDERYNIYNAVYAVAHAFHNMHLQQVDIKVLESWKGLIPRCMQVNDFLKNIRFINPIGDPVTVNQGRNLDAMYDILNVLHFPQGYVLKVKVGQFSPYFAHDQQLLLSEDMIEWATGSRQ---FSTSVCSMPCHPGFKKSHPEGKADCCFDCLRCPANEISNTT-DSEECVKCPEDWYADTEQTHCLPKAVTFLAYEDPLGMALVCLALCFSVLTALVLGVFLKHRETPIVKANNRTLSYILLTALIFCFLCSLLFVGNPNTTTCILQQTTFGILFTVSVSTVLAKTLTVVLAFRITLPGRRMRG-LMVSRIPKYIIPICTVVQIILYGIWLWTSPPFVDIDTHSEHGCITITCSKGSVMAFYCVLGYLGSLALVSFTVAFLARNLPDTFNEAKFLTFSMLVFCSVWITFLPVYHSSKGKVMVAVEVFSILASSMGLLGCIFIPKCYIILLRPDRNSIQKFRDKTHS------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8I6AGG5-1", "uniprot_id": "A0A8I6AGG5_RAT", "id": "A0A8I6AGG5-1", "name": "", "aln": "--------MADMEKAYTLIVFFLLLRLSFILCS----FPEATCFWRINHNE---NLESNMRKDCGFILFTIPVHLVEDHFR----VLLDF-----------------------------------------------PLPVNTYPYVLVMLFAIEEINKNPNLLPNSTLGFTFLGDQCDITSTDLNNLNMLSKSGEMNP-NYICEYS-FCDVALTGPTWTVSARVGT-------LLQLF---KIPQVML----SVTYGPFHDSLSDRDLFPHLYQIAPKDTSLVLAMVSLMIHFLWKWVGLVILDDDQGVQFLSDMKEEVKTNEICLAFVNMIPANMQLYIERAETYYFQIMTSSANVVIIYGNVNSTLEVSFRRWEMLGIWRLWITTSQWDVIS-RSRDFTIDSFHGTLSLSHHYQEISTFKHFIQKTNFSAYPEAVSLVRLGWIYLNCSV---SVCECKTLNHCLSNTILELLPWHSFDMAMNDERYNIYNAVYAVAHAFHNMRLQQVDIKVLESWEGLIPRCMQVNDFLKNVRLINPIGDPVNINQGRNLDAMYDIFNVLNFPQGYVLKVKVGQFSPYFAHDQQLFLSEDMIEWATGSRQ---FSTSVCSMPCHPGFKKSHQEGKADCCFDCSRCPANEISNTT-DSEECVKCPEDWYADTEQTHCLPKAVTFLAYEDPLGMALVCLALCFSVLTALVLGVFLKHRETPIVKANNRTLSYILLTALIFCFLCSLLFVGNPNTTTCILQQTTFGILFTVSVSTVLAKTLTVVLAFRITLPGRRMRG-LMVSRIPKYIIPICTVVQIILYGIWLWTSPPFVDIDTHSEHGCITITCSKGSVMAFYCVLGYLGSLALVSFTVAFLARNLPDTFNEAKFLTFSMLVFCSVWITFLPVYHSSKGKVMVAVEVFSILASSMGLLGCIFIPKCYIILLRPDRNSIQKFRDKTQMNQ----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "M0R9L8-1", "uniprot_id": "M0R9L8_RAT", "id": "M0R9L8-1", "name": "", "aln": "-------------MMFTSIFIVFLLKLPLLLSN----STENMCFWRANFNE---NCDGDLLHDCAFLIYTDEEPAPKDFFK----YLFKL-----------------------------------------------CLPSKIYQYVLSLYFAIMEINGNPYILPNVSLEIAYFRGECNGYLSLLTNLNIMTKYQHTLP-NYVCNPG-ACEIVLTGPLWKSSAQVAT-------ILQLN---FIP--------QITYGPFHPLLSDQIKFPNLHQIAPKDRFLCEAIVSLLFHFSWTWVGLVVEDNDQGIQFLLDIKGEMQRNGVCLAFVNVIPQNMQLFTTRAEIYYNKIITSSANVVIIYGEMNTALEVSFKHWKYLGTQKVWFTPSQWDVIT-REREFTSTSFHGTFTISQYHGDVSILNNFIYRMNLSKDTHYFSPERLGWMYSNCSL---LKSNCKTPNQCTSSNSWEWLPWHSFDMAMNDECYNVYNAIYAVAHALHEMILQKIDFQQRNNVSQLMQECLKVHEFLQKMKFFNPVGDIVVINQRTKRDAEYEIHMVWNFPQGLGMKVKIGRFFSHFLHDQKLYLYEDMIQWALGYSQ---IPTSICSMSCAPGFKKSYPEEKASCCFACSPCPENEISNAT-DLAQCVKCPDGQYANIERNHCFPKAVTFLDYADPVGIVLVCMALCLSTLSALILGIFVKKQNTPIVKANNRTLSYILLVSLTLCFLCSLLFIGHPSTARCVLQQITFGTLFTVAVSTILAKTITVLLAFSITVPGRRVTW-PLFVAS-KVIIPICSLFQLMLCGLWLGLSPPFVERDAHSEYGHIIIMCNKGSIIAFYCVLGYLGCLALASFIVAFLGRNLPDTFNEAKFLTFSMLVFCSVWVTFLPVFHSTKGKVMVAVEVFSILTSGAGLLGCIFIPKCYIIVLRQDRNFIKKVKGKNHS------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q1C1-1", "uniprot_id": "E9Q1C1_MOUSE", "id": "E9Q1C1-1", "name": "", "aln": "-------------MMFTSIFIVLLLKLPLLLCN----SAENMCFWRVKLNE---NCDGDLPQDCAFLLYTQVDPAPKDFLK----YLFKS-----------------------------------------------CLPSKIHQYLLSLYFAMEEINSNPYLLPNVSLGIEYFKGKCNGYLSLFTNLNIMTKYYHTFP-NYICDPG-ACEIALTGPLWISSAQVAT-------ILQLK---FIPQVR-----QITYGPFYPLLSDQSKFPNLHQIAPKNRFLPEAIVSLLFHFSWIWVGLVIQDDDQGIQFLLDIKEEMQRNGVCLAFVNVIPQNMHLFTTRAEKYYNQIITSSANVVILYGELNTALEVSFKHWKYLGTQKIWFTTSQWDAIT-REKDFSLTSFYGTLTISQYHGDVSTLNNFFQGANLSKDTHYFSSERLGWMYFNCSI---LKSNCKTPNQCTSSNLLEWLPRHSFDMAMNDESYNIYNAIYAVAHALHEMVLQKIDFQQLENVTQLMQECVQIHAFLENMQFLNPIGDVVIINQQAKTDAEYEIYMIWNFPQGLGVKVKIGRFYSYFLHDQKLYLYEDMIQWASGYSQ---IPPSVCSVSCAPGFKKFYLEEKPSCCFDCSPCPENEISNAT-DLTQCVKCPDGQYANIERNHCFPKVVTYLAYADPLGIVLACMALFLSMLSVLVLGIFVKNQYTPIVKANNRTLSYILLISLTLCFLCSLFFIGHPSTARCLLQQITFGILFTVAVSAVLAKTITVLLAFSITIPGRRVKW-LLLFGTHKVIIPICSLFQLIICGFWLGLSPPFVERDTHTEHGHIIIMCNKGSLIAFYSVLGYLGCLALASFIMAFLVRNLPDTFNEAKFLTFSMLVFCSVWVTFLPVHHSTKGKAMVAVEVFSILASSAGLLGCIFIPKCYIIVLRPDRNFIQRSKGKNHS------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "L7N221-1", "uniprot_id": "L7N221_MOUSE", "id": "L7N221-1", "name": "", "aln": "--------------MFTLIFLFLLLNIPLHVAD----FIHPRCFWKMKRNE---NKDRNQGTECTFVIQAVQQPVEKEYFS----HILNI-----------------------------------------------QTQTENRKYALALAFSINEINRNPDLLPNMSLIFKFSAENCVWENKLMSLMHSSLQNYDILP-NYLCEEYTECVMALTSLNWATTVTLYT-------ILNNFM---SEQFLQ-----ITYGPFHPVLSDHEKFPYLHQMASDHTSLALALVSFIIHFGWNWVGLVISDSDQGIQFLSYLRREMEKYTVCFAFVNMIPVNMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSP-SMKDFTFGNKYGTFDFQQHNSEISGFKNFVQTLNSVKC-PDEYLVELEWMHFNCEV---SASKCKPLKNCSSSYSFDWLMEHTFDMAFIEKSYYIYNAVYAFAHALHQFTFQKFDNLPKDNGKKHNYSCKKVDSSLRKTQFTNPVGDIVNMNQKGELQEEYDIFYIWNFPQGLGLRIKIGMFSPYFPNGQQVHLSEVMIRWAKGSTQ---VPTSVCSADCGPGSRKFEMDGMAACCFHCKPCPENEISNET-NVDNCVQCPEDQYANTEQNHCIHKAVVFLSYEEPLGMALSLLSLFFSAFTTVILGVIVKHHNTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSVTCFLQQITFGVVFTVALSTVLAKTITVVLAFKITASQRMMKY-FLVSGASNYIILICTLIQVIVCAVWLGASPPFVDIDAQSEHGHIIIVCHKGSVNAFYSILGYLALLSFGSFTLAFLSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKVMVAVEIFSTLASSAGILGCIFVSKCYTILFRPDRNSVEMTRVKSSFHAHIS-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "K7N674-1", "uniprot_id": "K7N674_MOUSE", "id": "K7N674-1", "name": "", "aln": "--------------MFTLIFLFLLLNIPLLVAD----FIHPRCFWKMKRNE---NKDRNQGTGCTFVIHAVQQPVEKEYFS----HILNI-----------------------------------------------QTQTENRKYALALAFSINEINRNPDLLPNMSLIFKFSAHNCVWESEIMNLMLLSLQNYDIFP-NYLCKEYTKCAMALTNLNWATTVTLYT-------ILNNII---SEQFLQ-----ITYGPFHPVLSDHEKFPYLHQMASDHTSLALALVSFIIHFGWNWVGLVISDSDQGIQFLSYLRREMEKYTVCFAFVNMIPVNMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSP-RMKDFTFGNKYGTFDFQQHNSEISGFKNFVQTLNSVKY-PDDYLVELEWMHFNCEV---SASKCKTLKNCSSNHSLEWLMVHTFDMAFIEKSYYIYNAVYAFAHALHQFTFQKFDNLPKDNGKEHNYSCKKVDPSLRKMQFTNPVGDIVNMNQRDKLQEEYDIFYIWNFPQGLGLRVKIGMFSPYLPNGQQVHLSEVIIKWTKGSTQ---VPTSVCSADCGPGSRKFGMDGMAACCFHCKPCPENEISNET-NVDNCAQCPEDQYANTEQNHCIHKAVVFLNYEEPLGMALSLFSLCFSAFTTVILGVIVKHHNTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSVTCILQQITFGVVFTVALSTVLAKTIVVVLAFKITASQRMMKY-FLVSGASNYIILICTLIQVIVCAVWLGASPPSVDIDAQSEHGHIIIVCHKGSVNAFYSILGYLALLSFGSFTLAFLSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKVMVAVEIFSTLASSAGMLGCIFVSKCYTILFRPDRNSVEMTRVKSSFHARVS-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9Q6I0-1", "uniprot_id": "V2116_MOUSE", "id": "E9Q6I0-1", "name": "Vomeronasal type-2 receptor 116", "aln": "--------------MFTLIFLFLFLNIPLLVAD----FISPRCFWKMKQNE---YRDRHHGTGCIFLILAIQQPVKKEYFS----HILNI-----------------------------------------------QTHTENHKYALALAFSIYEINRNPDLLPNMSLIFIFSADSCEWESELS-LIRFGLQNSDNLP-NYLCEELTKCILALTNMNWATTVTLHT-------ILSNFL---SDQLLH-----ITYGTFHPALSDHEKFPYLHQMASDHTSLALALVSFIIHFGWNWVGLVISDSDQGIQFLSYLRREMEKYTLCFAFVNMIPLNINLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSP-SMKDFTFGNKYGTFAFEQHHSEISGFKHFVQTLNSVKC-PDEYLVKLEWMHFNCEV---SASKCKTLKNCSSNHSLKWLMVHTFDMAFIEESYYIYNAVYAFAHVLHQFTFQKFDNLPKDNGKEHNYSCKKLYSYLRKNHFINPVGDRVSMNQRDKLQEEYDIVYIWNFPQGLGLRVKIGMFSPYFPNGQQVHLSEDMLKWARGSTQ---VPTSMCSADCGPGSRKFRMDGMAACCFHCKPCPENEISNET-NVDNCVQCPEDQYANTEQNHCIRKAVVFLSYEEPLGVALSLLSLCFSAFTTVVLGIFVKHHNTPIVKANNRTLTYLLLISLIFCFLCPLLFIGHPNSATCILQQLTFGVVFTVSLSTVLAKTITVVLAFKIIASQRMMKY-FLISGAINYIIPICILIQVIVCAVWLRASPPSVDIDAHSEHGQIIIVCHKGSVNAFYCVLGYLAILAFGSFTLAFLSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKVMVAVEIFSTLASSAGMLGCIFVPKCYTILFRQDQNSLEMIRVKSSSNVHVS-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9Q0E7-1", "uniprot_id": "E9Q0E7_MOUSE", "id": "E9Q0E7-1", "name": "", "aln": "--------------MFTLIFLFWLLNIPLLLAD----FISPRCFWKMKQNE---NRDRNQGTGCTFMIHAVQRPVEKEYFS----HILNI-----------------------------------------------QTHTENHKYALALAFSIYEINMNPDILPNMSLIFEFSVHNCVWESKLMSFMHVSLQNYDIFP-NYLCKEYTKCAMALTSLNWATTVKFNT-------ILNNFI---SQQFFQ-----ITYGPFHPVLSDHEKFPYLHQMASDHTSLAFGLVSFIIHFGWNWVGLVISDNDQGIQFLSYLKTEMEKNTICFAFVNMIPMSMNLYMSKAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWNVSP-GMKDFTFGNEYGTFAFGQHHSEISGFKHFVQTLNSVKC-PDEYLVKLEWMHFNCEV---SASKCKTLKNCSSNHSLEWLMVHTFDMAFIEGSYDIYNAVYAFAHALHQITFQKFDNLPKDNGKEHNYSCKKLYSFLRKTQFINPVGDRVNMNQRDKLQEEYDIFYIWNFPHGLGFKVKIGIFSPYFPNGQQVHLSEDMIEWAKGSAQ---MPTSVCSADCGPGSRKFRMDGMAACCFHCKPCPENEISNET-NVDYCVQCLEDQYANTEQNHCIRKIVVFLSYEEPLGVALSLISLFFSAFTIVVLGVIVKHHSTPVVKANNRTLTYILLISLIFCFLCPLLFIGHPNAATCILQQITFGIVFTVSVSTVLAKTITVVLAFKIIASQRMMKY-FLVSGAINYIIPVCILIQVIVCAVWLGASPPSVDIDGQSEHGQIIIVCHKGSVNAFYCVLGYLATLAIGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKVMVAVEIFSTLASSAGMLGCIFVPKCYTILFRPDQNSLEMIRVKSSSNARSS-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2KAL5-1", "uniprot_id": "A0A0G2KAL5_RAT", "id": "A0A0G2KAL5-1", "name": "", "aln": "--------------MFTMIFLFLLLNIPLLMVD----FIHPRCFWRMKQNE---DKDGNPGTGCTFFLQSVHWPVEKEYYS----DIFNI-----------------------------------------------QMHNENHKYALALAFAIYEINGNPDLLPNMSLIFEFTRDVCDWESQLNSVIQSSLKNHNILP-NYICKEFTKCPMALTGLNWTTTLKLHT-------ILNNFI---SQQFLQ-----VTYGPFHPVLSDNEKFPYLYQMASDDKSLALALVSFIIHFGWNWVGLAISNNDQGIQFLSYLRREMEKGTVCFAFVNMIPVNMHLYMSRAEMYYNQIMTSSTNVVILYGDTDSTLAVSFRMWESLGIEKIWVTNSWWAATL-SKKDHTFDNLYGTYAFGQHHGEISGFKNFVQTLNPAKY-SDEHLVKLEWMYFNCEV---SASKCKTLKNCSSNHSLEWLMVHTFDMAFTGGSYDIYNAVYSFAHALHEMTFQIFDNLPKDNGREHNYSCKKLCSFLRKTSFTNPVGDRVNMNQRHKQKEEYDIFYIWNFPQGLGIKVKIGMFSPYFPNGQQLHLSEDVLEWAKGSAQ---MPTSACSADCGPGFRKSWKDGMATCCFHCKPCPENEISNET-NVDVCARCPDDQYANIEQNRCIPKAVVFLSYEEPLGMALSLISLGFSVFTIVLLGVIVKHHNTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSAICILQQITFGVVFTVSVSTVLAKTITVILAFKVTASQRMMKY-FLVSRVPNYIIPTFTLFQVILCAVWLGASPPSIDIDAKSEHGHIIIACHKGSVTTFYCVLGYLGTLASGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKIMVAVEIFSTLASSAGMLGCIFVPKCYTVLFRQDQNSLVMIRMKSSSHAHIS-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PZA6-1", "uniprot_id": "E9PZA6_MOUSE", "id": "E9PZA6-1", "name": "", "aln": "--------------MFTLILLFLLLNIPLIVAD----FIDPRCFWRIKQNK---DEDGNLGSGCSFFIQAVQWPVEKEYFS----SILNT-----------------------------------------------QTHTENHKYALVLAFSINEVNRNSDLLPNMSLIFTFSALICDYESQLKSLIHLSLQNHEIFP-NYICNDD-VCAVALTGLNWTTTLTLYT-------ILNNFI---SHQFLH-----LTYGPFHPVLSDHEEFPYLYQMASEDTSLALAMVSFIIHFSWNWVGLAISDNDKGIQFLSYLRREMEKNTVCFAFVSMIPVNMHLYMTRTEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLDIKRIWVTTSQWAITT-GKKDFTFNNLYGTFAFGHHHGEISGFKNFVQTLNLLKY-SDEYLVKLEWMYFNCEV---SAPKCKTLKNCSSNHPLEWLMVRTFDMAFTEGSYAIYNAVYAVAHALHELTFQKFDNLPTDNVKEQNYACNKLGSFLRKIHFTNPVEDRVNMNQRNKLQENYDIFYVWNFPQGLGLKVKIGIFSPYIINGQQLHLSEDMLEWARGSTQ---MLTSVCSADCGPGFRKFGKNGMPACCFDCSPCPENEISNET-NVELCVPCPEDQYANTEQNHCIHKALIFLTYKDPLGMALSLMALCFSAFTAVVLLVFVKHHSTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSVTCILQQVTFGVAFTVAVSTVLAKTITILLAFRVTAPQRMMKY-FLVSGTYIYIIPICTLIQVIVCAVWLGAAPPSVDIDARSEHGHIIIVCNKGSVSAFYCVLGYLACLAFGSFTLAFLSRNLPSTFNEAKSITFSMLVFCSVWVTFLPVYHSTKGKVMVAVEIFSTLASGAGMLICIFVPKCYIILFMPDRNSLQMIRKKSSSHAHLS-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A140T8U3-1", "uniprot_id": "A0A140T8U3_MOUSE", "id": "A0A140T8U3-1", "name": "", "aln": "--------------MFTLILLFLLLNIPLIVAD----FIYSRCFWRIKQNK---DKDGNLGSGCALFIQAVQWPVEKEYFS----PILNT-----------------------------------------------QTYTENYKYILVFMFSINEVNRNSDLLPNMSLIFTFSALSCN-ESQLKSFIHLSLQDHDYFP-NYICNDY-ICGVALVGLKWETTLTLYT-------ILNNFM---SHQFLF-----LNYGPFHPAMSDHEEFPYIYQMASEDTSLALAMVSFIIHFSWNWVGLAISDNDEGIQFLSHLRREMEKNTVCFAFVSMIPVNMHLYMTRTEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLDIKRIWVTTSQWDIIT-SKKDFTFNNLYGTFAFGHHHGEISGFKNFVQTLDLLKF-SDEYLVKLEWMYFNCED---SAPKCKTLKNCSSNHPLEWLMVRTFDMAFTEGSYAIYNAVYAVAHALHELTFQKFDNLRPDNVKGQKYACNKLGSFLRKIHFTNPVGDRVNMNQRNKLQENYDIFYVWNFPQGLRLKVKIGIFSPYFINGQQLHLSEDMLEWARGSTQ---MLTSVCSADCGPGFRKFRRNGMPACCFDCRPCPENEISNET-NVELCVPCPEDQYANTEQNNCIQRAVIFLTYKDPLGMALSLMALCFSAFTAVVLLVFVKHHSTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSVTCVLQQVTFGVAFTVAVPTVLAKTITIVLAFRVTAPQRMMKY-FLVSGASIYIIPICTLIQVIVCAVWLGAAPPSVDIDARSEHGHIIIVCNKGSVSAFYCVLGYLACLAFGSFTLAFLSRNLPSTFNEAKSITFSMLVFCSVWVTFLPVYHSTKGKVMVAVEIFSTLASGAGMLICIFVPKCYIILFMPDRNSLQMIRKKSSSHAHLS-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZDW0-1", "uniprot_id": "D3ZDW0_RAT", "id": "D3ZDW0-1", "name": "", "aln": "--------------MLTLILLFFLLNIPLLVAS----FIYPRCFWSMKKNE---YQDRNLGTGCMFFILAVQQPVKKEYFS----HISNI-----------------------------------------------QTLTENQKYPLALAFSMNEINNNPALLPNMSLVFQFSEYVCFLESQYKHLFSLDLQNHEILP-NFICTEDIKCGVVLTGLSLVTTVTLHI-------ILNNFI---FKQFCH-----LTYGHFHPVLDDHENFPHLYQMASDDTSLALALISFIIHFSWNWVGLAISDNDQGTHFLSYLRREMEKNTVCFAFVNIIPVNMNLYMSRAELYYSQIMTSSANVVIIYGDTGNTLAVSFRMWDSLGIRRLWVTTSQWDVTP-FKKDFTFDNGYGTFGFGHRHSEISGFKYFVQTLNPFKY-SDEYLVKLEWMYVNCKI---LENKCKTLKNCSFNHSFEWLMTHTFDMAVIEGSYEIYNAVYAFAHALHEMTLPNVDNLLLDNYKEQYYNCKKVYSFLSKTQFTNPVGDTVNMNQRNKLKEEYDIFYNWNFPQGLGFKVKIGIFSPYFPKGQQLHLCENLIEWSTGSIQ---MPTSVCSADCGPGFRKVWKNGMPACCYDCSPCPENEISNET-NVELCVQCPEDQYANQEQNHCIHKARIFLTYDEPLGMALSLMALCLAALTVVVLGIFVKHHRTPIVKANNCTLTYILLIALIFCFLCPLFFIGHPNSATCILQQITFGVVFTLAISTVLAKTTTVILAFRVTAPHRMMKY-FLVSRASNYIIPICTLIQIIVCAIWLGASPPSVDIDAQSEHGHIIIVCNKGSITAFYCVLGYLACLAFVSFTLAFLSRNLPVTFNEAKSMTFSMLVFCSVWVTFLPVYHSTKGKVMVVVEIFSTLASSAGMLGCIFVPKCYTILCRPDRNSLQMIKEKSSSHTHIL-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2JYG8-1", "uniprot_id": "A0A0G2JYG8_RAT", "id": "A0A0G2JYG8-1", "name": "", "aln": "--------------MFTLILSFLLLNIPLQVTG----FIYPTCSWRIKENK---DKSGNERIGCFFLIQAVQKPVEKEYFS----HFFNT-----------------------------------------------QKHTEIHKYSLVLAFSMIEVNRNPDLLPNMSLVFSFREIICGWQPELSIFIEVNLDDYGVLP-NYTCKDDSLCGVVLTGLNWAPTLLLYT-------ILNNFK---SQQFPH-----LTYGHYHPVPSDHENFPYLYQMASDDTSLALALVSFIIHFSWNWIGLAFSDNDQGTHFLSYLKRGMEKNAVCLAFVSMIPVDMHLYMSRAEVYYSQILTSSANVVIIYGDTGSTLAVSFRMWESLGLQRLWITTTQLDVTP-SMK----ENIYGLFAFGHHHGVISGFKNFVQTLNPVTY-SNDNLAKLEWMHFNCEV---SASKWKTLKNFSSNHSLEWLMENTFEMTFSEGSYNIYNAVYTVAHVLHKMTFQKFHNLPNAKGKVQNYVCNKLGAPLRKIHFTNPVGDRINMNREDKLQEEYDIFYIWNFPQGLAFKVKIGLFSPYFINGQQLHLSGDMIEWARGSTQ---MPTSVCSADCGPGFRKFRKKEMSACCFDCSPCPENEISNET-NMEMCVLCPEDKYANTGQNDCIPKALIFLSYEDHLGMALSLMALGFSAFTAVVLGIFVKHHSTPIVKANNRTLTYILLLSLIFCFLCPLLFIGHPDSVTCILQQITFGVLFTVAISTVLAKTITVILAFKVTAPQRMMKY-FLLSGVSMYIIPICTLIQVIVCAVCLGVSPPSVDIDAQSEHGHIIVVCNNGSVTCFYSVLGYLACLTFVSFTLAFLSRNLPGAFNEAKSITFSMLVVCSVWVTFLPVYHSTKGKIMVAVEIISILASSSGMLVCIFIPKCYIILFRPEKNSLKMIREKSPSHTHIS-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2JYA5-1", "uniprot_id": "A0A0G2JYA5_RAT", "id": "A0A0G2JYA5-1", "name": "", "aln": "--------------MHTLILFFLLLNIPLLVVS----LIHPRCFWRMKQNE---EKNGNLKTGCIFAFGVVKWPVEKEYYY----NILST-----------------------------------------------QTNTENHQFSLALAFSMDEINKNPDLLPNKSLLFDFPFYSCKSHSELTTLIHGSVQQYDIFP-NYVCNNETMCTLLLTGPNWKISVILRT-------YLDLYK---SQQFLQ-----LTYGPFHPVLSDNEQFPYLYQMAPKETSLALALVSFLIHFSWNWIGLAISDNDQGNQFLSYLRTEMGKYTVCFAFVNMIPVNMQLFMTRTDVYYNQIITSSTNVVIVYGDTDSTLALGFKMWKSLGVQRIWVTTSEWDVIT-SKRDFTFDTFHSIIAFQHHHGEISGFKNFVQTLNPFKY-SDKYLVKLEWMYFNCEI---SASNCKTLKNCLYNESFEWLSEQTFDMAFSDGTHDIYNAAYAVAHALHEFFLQQGDNQQKYRGKWPNSVCLKLHSLLKKTHFTNPVGDRVIMNQREKMQEEYDIFYIWNFPQGLGLKVKIGEFSPYYSSGKQLWLFEDMIEWTTGNRQ---MPSSVCNSDCGPGFRKIWKEGMSTCCFDCIHCQENEISNET-NVDQCVKCPEDQYANPEQNHCIHKALIFLTYQETLGMTLSLVALCLSTLTAAILGVFVKYHTTPIVKANNCRLTYILLITLIFCFLCPLLYIGHPNSVTCVLQQVTFGIVFTVAISTVLAKTITVILAFKVTAPQRMIKY-FLISGVFNYIIPICTLIQVFVCTLWLGTSPPSVDFDPQSEHGHIIIVCNKGSVTAFYCMLGYLSCLALGSFTLAFLSRNLPGTFNEAKFLTFSMLVFCSVWITFLPVYHSTKGKVMVAVEIFSTLASSAGMLGCIFIPKCYIILLRPERNSLQRIREK---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "L7N2E1-1", "uniprot_id": "L7N2E1_MOUSE", "id": "L7N2E1-1", "name": "", "aln": "--------------MFTLMGVFFFLNIPLFMAN----FIDPRCFWRINLNE---IQDEYLGLTCAFILAAVQKPIEKDYFN----KTLNF-----------------------------------------------LKTTKNHKYALALAFAMDEINRNPDLLPNMSLIIRYTLGRCDGKTVIPTPYLFHKKKQSPIP-NYFCNEETMCSFLLTGPNWGVSISFWK-------YLDSFL---SPRILQ-----LTYGPFSSIFSDDEQYPYLYQMAPKDTSLALAMVSFILYFNWNWIGLVIPDDDQGNQFLLELKKQRENKEICFAFVKMISVDDISFEHKTEMYYKQIVMSSSNVIIIYEETIDFIDLIFRMWEPPVLQRIWITTKQWNFPT-SKRDITHGTFYGSLTFLPHHGGISGFKDFVQTWFHLKS-KDLYLVMPEWKYFKYES---SASKCKILKNNSSDASFDWLMEQKFDMAFSESSHNIYNAVHAIAHALHEMNLQQVDNQAIDNGKGASSHCLKVNSFLRKIHFTNPLGDKVIMKQRVIMQEEYDIFHFGNLSQHLGIKVKLGKFSPYFSHGRNFHLYVDMLEVATGSRK---MPSSVCSAECSPGFRRLWKDGMAACCFVCSPCPENEISNET-NMDKCVNCPEYQYANTEQNKCIQKGVTFLSYEDPLGMALALMAFCFSAFTAVVLCVFVKHHDTPIVKANNRILSYLLLISLMSCFLCSFFYIGHPNRATCVLQQITFGIVFTVAVSTVLAKTVTVVLAFKVTDPGRRLRN-FLVSGTPNYIIPICSLFQCVLCAIWLEVSPPFVDIDEHSQHGHIIIVCNKGSVTAFYCVLGYLACLALGSFTLAFLAKNLPDAFNEAKFLTFSMLVFFSVWVTFLPVYHSTKGKVMVAVEIFSILASSAGMLGCIFAPKIYIILMRPERNSTQKIKVRNSTQKIKEKSYF---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "L7N1Z4-1", "uniprot_id": "L7N1Z4_MOUSE", "id": "L7N1Z4-1", "name": "", "aln": "--------------MFTLMGVFFFLNIPLFMAN----FIDPRCFWRINLNE---IQDEYLGLTCAFILAAVQKPIEKDYFN----KTLNF-----------------------------------------------LKTTKNHKYALALAFAMDEINRNPDLLPNMSLIIRYTLGRCDGKTVIPTPYLFHKKKQSPIP-NYFCNEETMCSFLLTGPNWGVSISFWK-------YLDSFL---SPRILQ-----LTYGPFSSIFSDDEQYPYLYQMAPKDTSLALAMVSFILYFNWNWIGLVIPDDDQGNQFLLELKKQSENKEICFAFVKMISVDDISFEHKTEMYYKQIVMSSSNVIIIYEETINFIDLIFRMWEPPVLQRIWITTKQWNFPT-SKRDITHGTFYGSLTFLPHHGGISGFKDFVQTWFHLRS-KDLYLVMPEWKYFKYES---SASKCKILKNNSSDASFDWLMEQKFDMAFSESSHNIYNAVHAIAHALHEVNLQQVDNQAIDNGKGASSHCLKVNSFLRKIHFTNPLGDKVIMKQRVIMQEEYDIFHFGNLSQHLGIKVKLGKFSPYFSHGRNFHLYVDMLEVATGSRK---MPSSVCSAECSPGFRRLWKEGMAACCFVCSPCPENEISNET-NMDQCVNCPEYQYANTEQNKCIQKGVTFLSYEDPLGMALALMAFCFSAFTAVVLCVFVKHHDTPIVKANNRILSYLLLISLMSCFLCSFFYIGHPNRATCVLQQITFGIVFTVAVSTVLAKTVTVVLAFKVTDPGRRLRN-FLVSGTPNYIIPICSLLQCVLCAIWIEVSPPFVDIDEHSQHGHIIIVCNKGSVTAFYCVLGYLACLALGSFTLAFLAKNLPDTFNEAKFLTFSMLVFFSVWVTFLPVYHSTKGKVMVAVEIFSILASSAGMLGCIFAPKIYIILMRPERNSTQKIKVRNSTQKIKEKSYF---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "K7N705-1", "uniprot_id": "K7N705_MOUSE", "id": "K7N705-1", "name": "", "aln": "--------------MFTLMGVFFFLNIPLFMAN----FIDPRCFWRINLNE---IQDEYLGLTCAFILAAVQKPIEKDYFN----KTLNF-----------------------------------------------LKTTKNHKYALALAFAMDEINRNPDLLPNMSLIIRYTLGRCDGKTVIPTPYLFHKKNQSPIP-NYFCNEETMCSFLLTGPNWGVSISFWK-------YLDSFL---SPRILQ-----LTYGPFSSIFSDDEQYPYLYQMAPKDTSLALAMVSFILYFNWNWIGLVIPDDDQGNQFLLELKKQRENKEICFAFVKMISVDDISFEHKTEMYYKQIVMSSSNVIIIYEETIDFIDLIFRMWEPPVLQRIWITTKQWNFPT-SKRDITHGTFYGSLTFLPHHGGISGFKDFVQTWFHLRS-KDLYLVMPEWKYFKYES---SASKCKILKNNSSDASFDWLMEQKFDMAFSESSHNIYNAVHAIAHALHEMNLQQVDNQAIDNGKGASSHCLKVNSFLRKIHFTNPLGNKVIMKQRVIMQEEYDIFHFGNLSQHLGIKVKLGKFSPYFSHGRNFHLYVDMLEVATGSRK---MPSSVCSAEGSPGFRRLWKEGMAACCFICSPCPENEISNET-NMDQCVNCPEYQYANTEQNKCIQKGVTFLSYEDPLGMALALMAFCFSAFTAVVLCVFVKHHDTPIVKANNRILSYILLISLMSCFLCSFFFIGHPNRATCVLQQITFGIVFTVAVSTVLAKTVTVVLAFKVTDPGRRLRN-FLVSGTPNYIIPICSLLQCVLCAIWLEVSPPFVDIDEHSQHGHIIIVCNKGSVTAFYCVLGYLACLALGSFSLAFLAKNLPDTFNEAKFLTFSMLVFFSVWVTFLPVYHSTKGKVMVAVEIFSILASSAGMLGCIFAPKIYIILMRPDRNSTQKIKVRNSTQKIKEKSYF---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3UYA8-1", "uniprot_id": "G3UYA8_MOUSE", "id": "G3UYA8-1", "name": "", "aln": "--------------MFTLMGVFFFFNIPLFMAN----FIDPRCFWRINLNE---IQDEYLGLTCAFILAAVQKPIEKDYFN----KTLNF-----------------------------------------------LKTTKNHKYALALAFAMDEINRNPDLLPNMSLIIRYTLGRCDGKTVIPTPYLFHKKKQSPIP-NYFCNEETMCSFLLTGPNWGVSISFWK-------YLDSFL---SPRILQ-----LTYGPFSSIFSDDEQYSYLYQMAPKDTSLALAMVSFILYFNWNWIGLVIPDDDQGNQFLLELKKQRENKEICFAFVKMISVDDISFEHKTEMYYKQIVMSSSNVIIIYEETIDFIDLIFRMWEPPVLQRIWITTKQWNFPT-SKRDITHGTFYGSLTFLPHHGGISGFKDFVQTWFHLRS-KDLYLVMPEWKYFKYES---SASKCKILKNNSSDASFDWLMEQKFDMAFSESSHNIYNAVHAIAHALHEMNLQQVDNQAIDNGKGASSHCLKVNSFLRKIHFTNPLGNKVIMKQRVIMQEEYDIFHFGNLSQHLGIKVKLGKFSPYFSHGRNFHLYVDMLEVATGSRK---MPSSVCSAECSPGFRRLWKEGMAACCFVCSPCPENEISNET-NMDQCVNCPEYQYANTEQNKCIQKGVTFLSYEDPLGMALALMAFCFSAFTAVVLCVFVKYHDTPIVKANNRILSYILLISLMSCFLCSFFFIGHPNRATCVLQQITFGIVFTVAVSTVLAKTVTVVLAFKVTDPGRRLRN-FLVSGTPNYIIPICSLLQCVLCAIWLEVSPPFVDIDEHSQHGHIIIVCNKGSVTAFYCVLGFLACLALGSFSLAFLAKNLPDTFNEAKFLTFSMLVFFSVWVTFLPVYHSTKGKVMVAVEIFSILASSAGMLGCIFAPKIYIILMRPDRNSTQKIKVRNSTQKIKEKSYF---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9Q7U8-1", "uniprot_id": "E9Q7U8_MOUSE", "id": "E9Q7U8-1", "name": "", "aln": "--------------MFTLMGVFFFLNIPLFMAN----FIDPRCFWRINLNE---IQDEYLGLTCYFILAAVQKPIEKEYFN----KTLNF-----------------------------------------------LKTTKNHKYALALVFSMDEINRNPDLLPNMSLIIRYTLGRCDGKTVIPTPYLFHKKTKSPIP-NYFCNEETMCSFLLTGTHWEVSLSFWK-------YLDSFL---SPRILQ-----LTYGPFHSIFSDDEQYPYLYQMAPKDTSLALAIVSFIHYFNWNWIGLVIPDDDQGNQFFLELKKQCENKEICFAFVKMISVDDISLEEKTEMYYKQIVMSSSNVIIIYEETINFIDLIFRMWEPPVLQRIWITTKQWNFPT-SKRDITHDTFYGSLTFLPHHGGISGFKNFVQTWFHLRS-KDLYLVMPEWKYFKYES---SASKCKILKSKSSNASFDWLMEQKFDMAFSESSHNIYNAVYAVAHALHEMNLQQVDNQAIDNGKGASSHCLKVNSFLRKIHFTNPLGDKVIMKQRVIMQEEYDIFHFENLSQHLGIKVKLGKFSQYVSHGRNFHLYVDMLEVATGSKK---MPSSVCSAECSPGFRRMWKEGMAACCSVCSPCPENEISNET-NMDHCVNCPEYQYASTEQNKCIQKVVTFLSYEDPLGMALALIAFCFSAFTAVVLCVFVKHHDTPIVKANNRILSYILLLSLMSCFLCSFFFIGHPNRATCVLQQITFGIVFTVALSTVLAKTVTVVLAFKITDPGRRLRH-FLVSGTPNYIIPICSLLQCVLCAIWLAVSPPFVDIDEHSQNGHIIIVCNKGSVTAFYCLLGYLACLALGSFTVAFLAKNLPDTFNEAKFLTFSMLVFFSVWVTFLPVYHSTKGKVMVAVEIFSILASIAGMLGCIFAPKIYIILMSPERNSTQKIKENNSTQKIKEKSYF---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PW61-1", "uniprot_id": "E9PW61_MOUSE", "id": "E9PW61-1", "name": "", "aln": "--------------MLTLMGVFFFLNIPLFMAN----FIDPRCFWRINLNE---IQDEYLGLTCPFILAAVQKPIEKDYFN----KTLNF-----------------------------------------------LKTTKNHKYALALVFSMDEINRNPNLLPNMSLIIRYTLGRCDGKTGIPTPYLLHKKKQSPIP-NYFCNEESMCSFLLRGPNWEVSLSFWN-------FLDSFL---SPRILQ-----LTYGPFHSTFSDDEQYPYLYQMAPKDTSLALAMVSFIHYFNWNWIGLLIPDDDQGNQFLLELKKQSGNKEICFAFVKMISVDDILLEQKTEMYYQQIVMSSSNVIIIYEETINFIDLIFRMWEPPVLQRIWITTKQWNFPT-SKRDITHGTFYGSLTFLPHHGGISGFKNFVQTWFHLRS-KDLYLVMPEWKYFKYES---SASNCKMLKSNSSNASFDWLMEQKFDMAFSESSHNIYNAVYAVAHALHEMNLQQVDNQAVDNGKGASSHCLKVNSFLRKIHFTNTLGDKVIMKQRVIMQEDYDIFHFENLSQHLGIKVKLGKFSPYFSHGRNFHLYVDMLEVATGSRK---MPSSVCSAECSPGFRRLWKEGMASCCFFCSPCPENEISNET-NMDQCVNCPEYQYANTEQNKCIKKGVTFLSYEDPLGMVLALMAFCFSAFTALVLCVFVKHHDTPIVKANNRSLSYILLLSLMSCFLCSFFFIGHPNRATCVLQQITFGIVFTVAVSTVLAKTVTVVLAFKVTDPGRRLRQ-FLVSGTPNYIIPICSLFQCVLCAIWLAVSPPFVDIDEHSQHGHIIIVCNKGSVTAFYCVLGYLACLALGSFTLAFLAKNLPDTFNEAKFLTFSILVFFSVWVTFLPVYHSTKGKVMVAVEIFSILASSAGMLGCIFAPKIYIILMRPERNSTQNIKESNSTQKIKEKSNF---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "L7N2E5-1", "uniprot_id": "L7N2E5_MOUSE", "id": "L7N2E5-1", "name": "", "aln": "--------------MLTLMGVFFFLNIPLFMAN----FIDPRCFWRINLNE---IQDEYLGLTCAFILAAVQKPIEKDYFN----KTLNF-----------------------------------------------LKTTKNHKYALALVFSMDEINRNPDLLPNMSLIIRYTLGRCDGKTGIPTPYLLHKKKQSPIP-NYFCNEESMCSFLLTGPNWEVSLSFWN-------FLDSFL---SPRILQ-----LTYGPFHSTFSDDEQYPYLYQMAPKDTSLALAMVSFIHYFNWNWIGLLIPDDDQGNQFLLELKKQSGNKEICFAFVKMISVDDILLEQKTEMYYQQIVMSSSNVIIIYEETINFIDLIFRMWEPPVLRRIWITTKQWNFPT-SKRDITHGTFYGSLTFLPHHGGISGFKNFVQTWFHLRS-KDLYLVMPEWKYFKYES---LASNCKMLKSNSSNASFDWLMEQKFDMAFSESSHNIYNAVYAIAHALHEMNLQQVDNQAVDNGKGASSHCLKVNSFLRKIHFTNPVGDKLIMKERVIIQEDYDIFHFENLSQHLGIKVKLGKFSPYFSHGRNFHLYVDMLEVATGSRK---MPSSVCSAECSPGFRRLWKEGMAACCFVCRPCPENEISNET-NMDQCVNCPEYQYANTEQNKCIKKGVTFLSYEDPLGMVLALMAFCFSAFTAVVLCVFVKHHDTPIVKANNRILSYILLLSLMSCFLCSFFFIGHPNRATCVLQQITFGIVFTVAVSTVLAKTVTVVLAFKVTDPGRRLRH-FLVSGTPNYIIPICSLFQCVLCAIWLAVSPPFVDIDEHSQHGHIIIVCNKGSVTAFYCVLGYLACLALGSFIVAFLAKNLPDTFNEAKFLTFSMLVFFSVCVTFLPVYHSTKGKVMVAVEIFSILASSAGMLGCIFAPKIYIILMRPERNSTQNIKESNSTQKIKEKSNS---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V911-1", "uniprot_id": "G3V911_RAT", "id": "G3V911-1", "name": "", "aln": "--------------MLILMVIFFLLNIPFLLAN----FMDPRCFWKINLNE---IKDEVLGMTCSFILETVQKTMDKDYFN----QTLNV-----------------------------------------------LNTTTNHKYALALAFTVDEINRNPDLLPNMSLIIKYNLGHCDGKTVTTLSDLFNPNNHLHFP-NYLCNEGIMCLVLLTGPHWRASLYLWI-------SVYVYL---SPHFLQ-----LSYGPFYSIFSDNEQYPYLYQMGPKDSSLALAMVSFIIYFKWNWVGLFISDDDQGNQFLSELKKESQTKDICFAFVNMVSVSDVSYYHKTEMYYNQIVMSSTKVIIIYGETNSIIELSFRMWSSPVKQRIWVTTKQFDCPT-SKRDLTHGTFYGTLTFLHHYGEISGFKNFVQTRYNLRS-TDLYLVTPEWKYFNYEA---SASNCKILRNYLSNISLEWLMEQKFDMSFSDYSHNIYNAVYAIAHALHEKNLQEVENQAINNAKGENTHCLKLNSFLRKTHFTNSLGNRVIMKQREVVHGDYNIVHMWNFSQRLGIKVKIGQFSPHFPQGQQLHLYVDMTELATGSRK---MPSSVCSADCHPGFRRIWKEEMAVCCFVCNPCPENEISNET-NMDQCANCPEYQYANTEKNKCIQKGVIVLSYEDPLGMALALIAFCFSAFTVVVFWVFVKHHDTPIVKANNRILSYLLIVSLMFCFLCSFFFIGYPNRATCILQQITFGIFFTVAISTVLAKTITVVLAFKVTDPGRQLRI-FLVSGTPNYIIPICSLLQCILCAIWLAVSPPFVDIDEHSEHGHIIIVCNKGSITAFYCVLGYLACLAFGSFTIAFLAKNLPDTFNEAKFLTFSMLVFCAVWVTFLPVYHSTKGKVMVAVEIFSILASSAGMLGCIFAPKVYIILMRPDRN---------SIHKIREKSYF---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A8G4-1", "uniprot_id": "D4A8G4_RAT", "id": "D4A8G4-1", "name": "", "aln": "-------------MMLLLIFMFLLLQYSSDVYS----FDRSSCAAKTKTSV---YKDGDMVLAAFLPLFTITIDSASDNQSNNNFYIHQHVK-------------------------------------------ECKFIHSFHFIVLAMVYAIEEINRNPHILPNVSLGYDIYNVLFNEWWILNRCITWLSGPKKYVP-NYTCRREMKSIAALTGISWIISTNIGT-------LLELYK---YPQL--------TIGSFDPNLNNHEQFHDIYQIAYKDMSLTHGIVSLLNYFHWNWVGLIVSEGQNGFQIISELRAEMDRNKICVDFVEMIRVSEVSYLPSYLLSPTHLAKSTANVIITYGDSDFMRGFLFYLRQILVTRKVWIMNSDWDVII-QSKHFILQSFHGSLIFAHHHKETSGYRNFIQTVHPSKYPEDFYLTRFWFYFFNCSF---ADDDCNTLENCLPNASLHETPGSHFDMVMTEFAYNIYNAVYAVAHSLHKMLLQQVEVTPVKEAEDLIFSAWQLHPFLKNMQFTNPAGEQVNLNEKMKLNADYDILNYWNFPEGLQLKVKVGQFSPYGPLGQQLSLSEDTIEWPTEITE---TPRSICSESCGPGFRKSLPEGKVSCCFDCVPCPENEISNET-DVDQCMQCLDHQYANTAQNHCLQKSMTFLDYEDPMGISLSCIALCFSALTSLVLSIFLKQKNTPIVKANNRTLTYILLIALNFCFLCSFLFIGHPNTATCILQQTTFAVVFTVAVSTVLAKTITVVLAFKVTAPGRRIRW-LLVTRAPNFIVPICTLIQIILCGVWLGNSPPFIDTDTRSEHEHIIIMCNKGSVTAFYCVQGYLGALALGSFTLAFLARNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKHMVVVEVFSILVSSAGLLGCIFAPKCYIILLRPQRNSIQGHRDKIHYNYKTS-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8V5L1A2-1", "uniprot_id": "A0A8V5L1A2_MOUSE", "id": "A0A8V5L1A2-1", "name": "Parathyroid cell calcium-sensing receptor", "aln": "--------------MWLCAFIFAFFVCLSG------SDLSGPRAWILPRQSPHFDRPGDVIVGGSFSIFHFSDGTPSDFTAPPTGLQTS------------------------------------------------SVSMWGYRVAQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQEEPIP-NYTCQHGSPQAALVGDTRSSLSVSMAR-------LLGLYK---FS--------QVSYSSSLPSLSDKIQFPSFLRTLTSDITSSHAVTQLIIHFQWSWVIILAQDDDFGQQASSLATQQLSPAGVCIEYHLHVPS--HQSLGKIEETVQKMQKCTSKVVLVFLSNSNFQLILHGLLGVPVSGQVWVSKGTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSKIDAA---YTAVYSIAHALHNMLACEHQERKGTNSHN--FHSWQLLHALKKVHFKTLDGIKIMFDANGDLVTKFDIFQGQKTPAGVFHLVHVGMIDPQVSSGNKMMVQLKEDLQV---------PSSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQR-DMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFKVTRPRSRIQI-CLSPGTSTLVVLIASLIQVVLCGVWLATFPPFPDKDMLSEPQHIVIQCHDGSGATFFCVLGYLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYYSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPSWLKQGHHI------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A3B2W422-1", "uniprot_id": "A0A3B2W422_MOUSE", "id": "A0A3B2W422-1", "name": "Parathyroid cell calcium-sensing receptor", "aln": "--------------MWLCAFIFAFFVCLSG------SDLSGPRAWILPRQSPHFDRPGDVIVGGSFSIFHFSDGTPSDFTAPPTGLQTS------------------------------------------------SASMWGYRVTQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQKEPIP-NYTCQHGSPQAALVGDTRSSLSVSMAR-------LLGLYK---FP--------QVSYSSSLPSLSDKIQFPSFLRTLTSDITSSHAVTQLIIHFQWSWVIILAQDDDFGQQASSLATQQLSPAGVCIEYHLHVPS--YQSLGKIEETVQKMQKCTAKVVLVFLSNLNFQLILRGLLGVPVSGQVWVSKGTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSKIDAA---YTAVYSIAHALHNMLACEHQERKGTNSHN--FHSWQLLHALKKVHFKTLDGIKIMFDANGDLVTKFDIFQGQKTPAGVFHLVHVGMIDPQVSSGNKMMVQLKEDLQVSSLNAEETVPTSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFTDQR-DMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFVLALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFRVTRPRSRIQI-CLSPGTSTFVVLIASLIQVVLCGVWLATSPPFPDKDMISEPQHIVIQCQEGSGATFFCVLGYLGFLAGGTFSVAFLARGLPDIFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLKQGYCAQQEKQGEMLQRRYKFSGESPEPNI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A3B2W4A7-1", "uniprot_id": "A0A3B2W4A7_MOUSE", "id": "A0A3B2W4A7-1", "name": "Parathyroid cell calcium-sensing receptor", "aln": "--------------MWLCTLLSVLFGCLSG------SALSGPRVWIIPRQSPRFDRPGDVIVGGSFSIFHFSDGTLSNFTAPPPVLKTS------------------------------------------------SASMWSYRVAQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQEEPIP-NYTCQHGSPQAALVGDTRSSLSVSMAR-------LLGLYK---FP--------QVSYSSSLPSLSDKIQFPSFIRTLTSDLTCSHAVTQLVIHFQWSWVIILAHDDDFGQQASSLATQMLTPAGVCIEYHLHVPS--HQSFGKIEETVQKMQKCTARVVLVFLSNSNFQLILHGLLAVPVSGQVWVSMDTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSRIDAA---YTAVYSIAHALHNMLACEHQERKGTNSHN--FHSWQLLHNLRNVYFKTSDGNKIMFDANGDLVTQFDIFQGKKTPAGVFHLVHVGLIDPQASSGNKMMVQLKQDLQVSSLNAEITVPTSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFTDQR-DMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTIFAVVFTVAVSSVLAKTLTVVLAFRVTRPRSRIQV-CLSSGASTSVVLIASLIQVVLCGIWLITSPPFPDRDMISEPRHTVIQCHEGSGANFFCVLGFLGFLAGGTFSVAFLARGLPDVFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLRQGHQVQHNRQCEMLQRRCVSSGESLGSSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A3B2WBA1-1", "uniprot_id": "A0A3B2WBA1_MOUSE", "id": "A0A3B2WBA1-1", "name": "Parathyroid cell calcium-sensing receptor", "aln": "MGLSCHWLSDPLAGMWLCTLLPVLFGCPSG------SALSGARAWLLPRQSPHFDRPGDVIVGGSFSIFRFSNGTLSNFTAPPAGLQTS------------------------------------------------SVSMWGYRVAQSFVFAIEEINRSTHLLPNLTLGFSIRNSGDSAHGALYETMGFLTGQEEPIP-NYTCQHGSPQAALVGDTRSSLSVSMAR-------LLGLYK---FP--------QVSYSSSLPSLSDKIQFPSFIRTLTSDLTSSHAVTQLIIHFQWSWVIILAHDDDFGQQASSLASQVLTPAGVCIEFYLYVPS--HQSLGKIEETVRKMQKCTARVVLVFLSNYNFQLILYGLLAVPVSGQVWVSKDTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCMWPYQNITVTEGVQFCTGNESLKNKPHPFPEVSKIDAA---YTAVYSIAHALHDMISYEHQDGKGTNSQD--FQPWQLLHVLRKVHFKTPDGSEIMFDANGDLVTKFDIFQGQKTPDGVFHLVCVGLIDPQASSGNKMMVQKKMLKYQMK---HAQVPTSVCSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQR-DMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFKVTRPRSRIQI-CLSPGTSTLVVLIASLIQVVLCGVWLATFPPFPDKDMLSEPQHIVIQCHDGSGATFFCVLGYLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYYSARGKSTVAVEIFSILASTAGLLGGIFIPKCCIILLKPEKNTSSWLRQGHHV------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GK53-1", "uniprot_id": "A0A8I6GK53_RAT", "id": "A0A8I6GK53-1", "name": "", "aln": "--------------MWLCTFLFVLLGCLPG------SALSEPRSWILPRQSPHFDRPGDVMVGGSFSIFCFSDGTLSNFTAPPTGLQAS------------------------------------------------RVSMWGYRVAQSFVFAIEEINKSTQLLPNLTLGFSIQNSGDSVHGALYETMGFLTGQEEPIP-NYTCCHGSPQAALVGDTRSSLSLPMAR-------LLGLYK---FS--------QISYSSSLPSLSDKIQFPSFLRTLPSDLTSCHAVTQLIIRFQWSWLIILSQDDDFGEQASSLATQQLSAAGVCIEFHLDVPS--QHSLGKIEETVQKMQKCTARVVLVFLSNSNFQLILSGLLAASVSGQVWVSNDTLHIAMALSIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLHPSQIPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQVCSGNESLKNKPYPFPEVSKIDAA---YTAVYSIAHALHDMVACEHQDGIDTNPQD--FHPWQLLHVLKKVHFRTPDGSEIMFDANGDLVTKFDILQGQKTLNGVFHLVHVGMIDPQASSGNIMMIQLKEDLQVSSMNAEITVPTSICSERCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQR-DMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALMAILLAGLALLVLGVFLKHRDTPVVRVNNRTLSYFLLISLSLCSLCSLLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTVTVVLAFRVTKSGSRIQV-CLSPGASTSVVLIASLIQVVLCGVWLATSPPFPERDMISEPQHIVIQCQEGSGATFFCVLGFLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLRQGHCAHQDRQCSLFH--------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3AV03-1", "uniprot_id": "A0A8M3AV03_DANRE", "id": "A0A8M3AV03-1", "name": "", "aln": "--------------MYNNVLLIVTLQCIITRLYVVYGNRLGSCILQGDPQPPVLFDEGDFIIGGAFSIHYYLRTEKHTYTMRPQSLECSG-----------------------------------------------SMDFRELRFARVLQFAIQEINNSSDLLPGITLGYRIYDSCGSVPMAVKLSFQLANGLDLIFNDNDSCSKSAAVAALVGESGSTPSISISR-------LYGPFG---IP--------QVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEEEGICVEYSEAYYR--TQPRSKLMRVADVIRRSTARVIVAFMASGDMRLLLEELSQQPLPPMQWIGSEAWFTDPEMLR---FNMCIGGVGFAIPRSVIPGFRTFLLDLSPQRAMKFPLLTEFWESSFSCSLKQQTGPSTG-MPACDGTEDLGRLKNPYTDTSQLRISNMVYKATYAIAHALHGIICNEK---KCNKNIK--IEPREVLDKLKQVKFSK-NNYSVSFDAYGDPVAVYELVNWQLQKDGSIDFVTVGKYDSSQPKGKEFSLSRAIIWYDGT----EEVPVSVCSESCPPGTRKAVQKGRPVCCYDCINCADGEISNDT-DCLDCHECLSDYWPNNEKNKCLRKPVEFLSWDEILGIILAAFSVAGSLVALSMALVFYKNRASPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMK-WFGPSQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWAVLGYIGLLAFLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKFTVAVEIFAILASSFGLILCIFAPKFFIIIFRPERNTKKHIMGKVPSKAL---------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: * * *: :.: : :* : : .::.* : : . *. . : .. . : *.* :: ** * : : : . : .:: : :. . . * *. .* : ** * * . .:: : * * :.. : *: : * : : *. * :. : . : : * . *:*:.** :: :*: :* * **.: :: * *.*:: *. *.:.:. :*.** .:: ** . : : : :.* . : ** : : * ** * *:: *: : :**: : ** ***:* :***:*: :* :*:* . *: * : **::: *.* :: :* * :: ", "identical_positions": 76, "similar_positions": 127, "identity": "7.8%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100726-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54802-1", "uniprot_id": "ANAG_HUMAN", "id": "P54802-1", "name": "Alpha-N-acetylglucosaminidase", "aln": "MEAVAVAAAVGVLLLAGAGGAAGD------------EAREAAAVRALVARLLGPGPAADFSVSVERALAAKPGLDTYSLGGGGAARVRVRGSTGVAAAAGLHRYLRDFCGCHVAWSGSQLRLPRPLPAVPGELTEATPNRYRYYQNVCTQSYSFVWWDWARWEREIDWMALNGINLALAWSGQEAIWQRVYLALGLTQAEINEFFTGPAFLAWGRMGNLHTWDGPLPPSWHIKQLYLQHRVLDQMRSFGMTPVLPAFAGHVPEAVTRVFPQVNVTKMGSWGHFNCSYSCSFLLAPEDPIFPIIGSLFLRELIKEFGTDHIYGADTFNEMQPPSSEPSYLAAATTAVYEAMTAVDTEAVWLLQGWLFQHQPQFWGPAQIRAVLGAVPRGRLLVLDLFAESQPVYTRTASFQGQPFIWCMLHNFGGNHGLFGALEAVNGGPEAARLFPNSTMVGTGMAPEGISQNEVVYSLMAELGWRKDPVPDLAAWVTSFAARRYGVSHPDAGAAWRLLLRSVYNCSGEACRGHNRSPLVRRPSLQMNTSIWYNRSDVFEAWRLLLTSAPSLATSPAFRYDLLDLTRQAVQELVSLYYEEARSAYLSKELASLLRAGGVLAYELLPALDEVLASDSRFLLGSWLEQARAAAVSEAEADFYEQNSRYQLTLWGPEGNILDYANKQLAGLVANYYTPRWRLFLEALVDSVAQGIPFQQHQFDKNVFQLEQAFVLSKQRYPSQPRGDTVDLAKKIFLKYYPRWVAGSW-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88325-1", "uniprot_id": "O88325_MOUSE", "id": "O88325-1", "name": "Alpha-N-acetylglucosaminidase", "aln": "MEAAGLAVILGFLLLAG--GSVGD------------EAREAKAVRELVVRLLGPGPAANFLVSVERALADESGLDTYSLSGGGGVPVLVRGSTGVAAAAGLHRYLRDFCGCQVAWSSAQLHLPWPLPAVPDGLTETTPNRYRYYQNVCTHSYSFVWWDWARWEQEIDWMALNGINLALAWNGQEAIWQRVYLALGLTQSEIDTYFTGPAFLAWGRMGNLHTWDGPLPRSWHLSQVYLQHRILDRMRSFGMIPVLPAFAGHVPKAITRVFPQVNVIKLGSWGHFNCSYSCSFLLAPGDPMFPLIGNLFLRELTKEFGTDHIYGADTFNEMQPPFSDPSYLAATTAAVYEAMVTVDPDAVWLLQGWLFQHQPQFWGPSQIRAVLEAVPRGRLLVLDLFAESHPVYMHTASFHGQPFIWCMLHNFGGNHGLFGALEDVNRGPQAARLFPNSTMVGTGIAPEGIGQNEVVYALMAELGWRKDPVPDLMAWVSSFAIRRYGVSQPDAVAAWKLLLRSVYNCSGEACSGHNRSPLVKRPSLQMSTAVWYNRSDVFEAWRLLLTAAPNLTTSPAFRYDLLDVTRQAVQELVSLCYEEARTAYLKQELDLLLRAGGLLVYKLLPTLDELLASSSHFLLGTWLDQARKAAVSEAEAQFYEQNSRYQITLWGPEGNILDYANKQLAGLVADYYQPRWCLFLGTLAHSLARGVPFQQHEFEKNVFPLEQAFVYNKKRYPSQPRGDTVDLSKKIFLKYHP--QPDSL-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B5D7-1", "uniprot_id": "A0ACD6B5D7_DANRE", "id": "A0ACD6B5D7-1", "name": "Alpha-N-acetylglucosaminidase", "aln": "MIHCIRCALIALLFMTLLHSVCGDFQTLAHLRAKASDKSQSRAVLDLLRRLLG-NRAREFIVSVNRTLSAD-GLDVCELRSAKNNKVVAVGSTGVAVATGIYNYLKYFCNCHVSWAGDQLNLPRPLPALTGVLRISTPHRFRYYQNVCTASYSSVWWDWPRWQREIDWMALNGINLPLAFTGQEVLWQEVYLSLGLNQTELDRFFSGPAFLAWNRMGNLFQWGGPLPQSWHVKQLYLQFKILDRMRSFGMIPVLPAFSGIVPEGITRLFPKANVTKLSPWSHFNCTYSCAYVLDPRDPLFHRIGALFLTQVIEEFGTDHIYNTDTFNEMPPASSDPTYLASISRAIFNTMTSVDPQAIWLMQGWLFISDPSFWKADQVKALLHGVPLGRMIVLDLFAESMPVYSSTNSFYGQPFIWCMLHNFGGNSGLFGTVDSINSGPFNAVRFPNSTLVGLGMTPEGIEQNPVIYELMSELAWRKDPVN-LYKWVSLYALRRYGSMDENLALAWQLLFRSVYNCTLPKYKNHNRSPLVHRPSLHMQTDIWYDPADFYRAWKLLFEAAPGLVTLETFRYDLVDVTRQALQLLTTEFYKDIKSAFQTQKLSDLLTAGGVLVYDLLPELDRILSSNEHFLLGAWLQQAQSQGVDEHEAHLYDINARNQITLWGPNGEILDYASKEWAGLVEDYYLQRWGLFVNTLVECLDRGRPFKQDVFNQAVFQVEKGFVFNQRKYPTKPLGDTYDIARRIFLKYYPYALKKTEMKKTS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .. :..*::: . ** : :: ** *: **** . * :* ***:*:*: . ***. .* .. * . ******.*:*::.**: **.*:*:*:. **.** ****:.. * :**:*:******** *** *****.**::************.**:.***.:**.***:***.*:*:: :*:*******.*****. *.**** ***:.*:***.::**:****** ******:* **:.:**:**:.** *:..*.****:***:::* * **:* ** *** :: :********.:****** *. *:*:***: : *::::*.:**.:*:**:***** :*.** . *::*:* .** **::******** *** * ** *************** ****::: :* ** * *****:** *::**** ** *:* **:**.****** * **: :* **** . : **:**:******: .*******:****:*.* :**: :*.:.**:**: :**.*.* :*****:*:****:* *.: *:: ::*: .::* ** ***:*.*.*** **.:*:*..:****:**:**: .*.* **.:*: *:* *:*****:*:*****.*: **** :** ** **: :*...: :* **:*. *:: ** :*:.** .:::**::* *** *::::*****:* : ", "identical_positions": 400, "similar_positions": 209, "identity": "52.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100727-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55156-1", "uniprot_id": "CLIP2_RAT", "id": "O55156-1", "name": "CAP-Gly domain-containing linker protein 2", "aln": "-------------------------------------------MQKPSGLKPPGRGGKHSSPVGRPSIGSASSSVVASASGSKEGSPLHKQASGPSSAGATTTVSEKPGPKAAEVGDDFLGDFVVGERVWVNGVKPGVVQYLGETQFAPGQWAGVVLDDPVGKNDGAVGGLRYFECPALQGIFTRPSKLTRQPAAEGSGSDGHSVESLTAQNLSLHSGTATPPLTGRVIPLRESVLNSSVKTGNESGSNLSDSGSVKRG-DKDLHLGDRVLVG---GTKTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAKAKKTKRMAMGVSALTHSPSSSS------------ISSVSSVASSVGGRPSRSGLLTETSSRYARKISG-----------TTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIALLKAQHEQYVAEAEEKLQRARLLVENVR---------------------------------KEKVDLSNQLEEERRKVEDLQFR------VEEESITKGDLETQTQLEHARIGELEQSLLLEKAQAERLLRELADNRLTTVAEK-----------------------------SRVLQLEEELSLRRGEIEELQHCLLQSGPPPADHPE------AAETLRLR-----------------------------------ERLLSASKEHQRDSTLLQDKYEHMLKTYQTE-------------------------------------------------VDKLRAANEKYAQEVADLKAKVQQATTENMGLMDNWKSKLDSLASDHQKS----------LEDLKATLNSGPGAQQKEIG-------ELKALVEGIKMEHQLELGNLQAKHDLETAMHG-------------------------------------------------------KEKEGLRQKLQEAQEELAGLQQHWRAQLEEQA-----------------------------------AAP-AELQEAQDQCRDAQLRVQELEGLDV--------------------------EYRGQAQAIEFLKEQISLAEKKMLDYEMLQRAEAQSRQEAERLREKLLVAENRLQAVESLCS--------------------------------------------------------------------AQHSHVIESNDLSEEKIRMKETVEGLQDKLNKRDKEVAALTSQMDMLRAQVSALENKCKSG---------------------EKKIDSLLKEKRRLEAELEAVSRKTHDASGQLVHIS---------------------------------------------------------------QELLRKERSLNELRVLLLEANRHSPGPERDLSREVHKAEWR-IKEQKLKDDIRGLREKLTGLDKE---KSLSEQKRYSLIDP-----------------------ASAPELLRLQHQLVSTEGCLRDALDQAQQVERLVEALRGCSDRTQTISNSGSANGIHQPDKAHKQEDKH------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0H8-1", "uniprot_id": "CLIP2_MOUSE", "id": "Q9Z0H8-1", "name": "CAP-Gly domain-containing linker protein 2", "aln": "-------------------------------------------MQKPSGLKPPGRGGKHSSPVGRPSVGSASSSVVASTSGSKEGSPLHKQASGPSSSGAATTVSEKPGPKAAEVGDDFLGDFVVGERVWVNGVKPGVVQYLGETQFAPGQWAGVVLDDPVGKNDGAVGGVRYFECPALQGIFTRPSKLTRQPTAEGSGSDTHSVESLTAQNLSLHSGTATPPLTGRVIPLRESVLNSSVKTGNESGSNLSDSGSVKRG-DKDLHLGDRVLVG---GTKTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAKAKKTKRMAMGVSALTHSPSSSS------------ISSVSSVASSVGGRPSRSGLLTETSSRYARKISG-----------TTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIALLKAQHEQYVAEAEEKLQRARLLVENVR---------------------------------KEKVDLSNQLEEERRKVEDLQFR------VEEESITKGDLETQTQLEHARIGELEQSLLLEKAQAERLLRELADNRLTTVAEK-----------------------------SRVLQLEEELSLRRGEIEELQHCLLQSGPPPADHPE------AAETLRLR-----------------------------------ERLLSASKEHQRDSTLLQDKYEHMLKTYQTE-------------------------------------------------VDKLRAANEKYAQEVADLKAKVQQATTENMGLMDNWKSKLDSLASDHQKS----------LEDLKATLNSGPGAQQKEIG-------ELKALVEGIKMEHQLELGNLQAKHDLETAMHG-------------------------------------------------------KEKEGLRQKLQEVQEELAGLQQHWREQLEEQA-----------------------------------SQHRLELQEAQDQCRDAQLRAQELEGLDV--------------------------EYRGQAQAIEFLKEQISLAEKKMLDYEMLQRAEAQSRQEAERLREKLLVAENRLQAAESLCS--------------------------------------------------------------------AQHSHVIESSDLSEETIRMKETVEGLQDKLNKRDKEVTALTSQMDMLRAQVSALENKCKSG---------------------EKKIDSLLKEKRRLEAELEAVSRKTHDASGQLVHIS---------------------------------------------------------------QELLRKERSLNELRVLLLEANRHSPGPERDLSREVHKAEWR-IKEQKLKDDIRGLREKLTGLDKE---KSLSEQRRYSLIDP-----------------------ASPPELLKLQHQLVSTEDALRDALNQAQQVERLVEALRGCSDRTQTISNSGSANGIHQPDKAHKQEDKH------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UDT6-1", "uniprot_id": "CLIP2_HUMAN", "id": "Q9UDT6-1", "name": "CAP-Gly domain-containing linker protein 2", "aln": "-------------------------------------------MQKPSGLKPPGRGGKHSSPMGRTSTGSASSSAAVAAS-SKEGSPLHKQSSGPSSSPAAAAAPEKPGPKAAEVGDDFLGDFVVGERVWVNGVKPGVVQYLGETQFAPGQWAGVVLDDPVGKNDGAVGGVRYFECPALQGIFTRPSKLTRQPTAEGSGSDAHSVESLTAQNLSLHSGTATPPLTSRVIPLRESVLNSSVKTGNESGSNLSDSGSVKRG-EKDLRLGDRVLVG---GTKTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAKAKKTKRMAMGVSALTHSPSSSS------------ISSVSSVASSVGGRPSRSGLLTETSSRYARKISG-----------TTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKEIALLKAQHEQYVAEAEEKLQRARLLVESVR---------------------------------KEKVDLSNQLEEERRKVEDLQFR------VEEESITKGDLETQTQLEHARIGELEQSLLLEKAQAERLLRELADNRLTTVAEK-----------------------------SRVLQLEEELTLRRGEIEELQQCLLHSGPPPPDHPD------AAEILRLR-----------------------------------ERLLSASKEHQRESGVLRDKYEKALKAYQAE-------------------------------------------------VDKLRAANEKYAQEVAGLKDKVQQATSENMGLMDNWKSKLDSLASDHQKS----------LEDLKATLNSGPGAQQKEIG-------ELKAVMEGIKMEHQLELGNLQAKHDLETAMHV-------------------------------------------------------KEKEALREKLQEAQEELAGLQRHWRAQLEVQA-----------------------------------SQHRLELQEAQDQRRDAELRVHELEKLDV--------------------------EYRGQAQAIEFLKEQISLAEKKMLDYERLQRAEAQGKQEVESLREKLLVAENRLQAVEALCS--------------------------------------------------------------------SQHTHMIESNDISEETIRTKETVEGLQDKLNKRDKEVTALTSQTEMLRAQVSALESKCKSG---------------------EKKVDALLKEKRRLEAELETVSRKTHDASGQLVLIS---------------------------------------------------------------QELLRKERSLNELRVLLLEANRHSPGPERDLSREVHKAEWR-IKEQKLKDDIRGLREKLTGLDKE---KSLSDQRRYSLIDR-----------------------SSAPELLRLQHQLMSTEDALRDALDQAQQVEKLMEAMRSCPDKAQTIGNSGSANGIHQQDKAQKQEDKH------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q4W2-1", "uniprot_id": "A0A8M9Q4W2_DANRE", "id": "A0A8M9Q4W2-1", "name": "", "aln": "-----------------------------------------MNMLKSSGLKIPGRGPKHASPVGRTTAGPSTS-----PAAQKEGCPYKQTTPTPSSN-----ASDKSSSKASEVGDEVAGDFVVGERVWVNGVKPGVIAYLGETQFSPGQWAGVVLNDLVGKNDGSVNGVRYFECQALQGIFTRPSKLTRQPIGDGSDEQ---------QNAQLQGGAGASGQR-VVMPLREGILNSSVKTGNESGSNMSDSGSVKKGGEKDLKVGDRVLVG---GTKTGVVRYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPPKFGLFAPIHKVIRIGFPSTSPAKAKKSKRMAMGVSSLAHSPSSSS------------ISSVSSVASSVGGRPSRTGLLTETSSRYARKISG-----------TTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICEVEKELAALKARHLQYATETESNLQQVRAMLASTQ---------------------------------KDKMELANQLEEEKRKVEDLQFR------VEEESITKGDLETQTKLEHARIRQLEQCLHLEKSKAERLQKELEEKMQTTVEEK-----------------------------TRVMQLEEELALRKAEVEELQVRFQRGSSGSATDAEDGEPGITSETLVLR-----------------------------------EQLLSVGRERREESSQLRERYEASLSTSQKE-------------------------------------------------IERLKAITERQGQEISDLKQRLQQATRENMEMMDSWKAKLDALVGDHQRA----------LEELKASLTTDCGSGEINGGEGEGSLPEMRAALEGLKMEHQLELENLKAKHEIDAAVMA-------------------------------------------------------KEREDLRSRLQELRDQLEDSEENWKIQVETKS-----------------------------------NQHTLEIKEVSEKLQKAELRIVDLDKSHE--------------------------ERE---KVNQLLKEQLMLAEKKMVDYEALQKAEAQSRAEILSLQEKLRVTENRLQAVEADHT--------------------------------------------------------------------TQDVNMIENNDNSDEKVKLKQNVEETLEKLTKREKEVSTLTTQVDALKTQITALEEKVRLG---------------------EKTADGLIKEKTRLEAELETMTKKSHDASGQLVNIS---------------------------------------------------------------QELLKKERSLNELRVLLLESPRHSAGVDRDLSREVHRAEWR-MKEQKLQDDIKTLREKLLLLGRE---RSSPDHRRYSMMDPS----------------------ASDTEVARLRQRLLNTEDALRNALEHNQHVDQLVQAMRTRPDKNQAHASANSANGIHQEDTSFTQEEEH------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJE5-1", "uniprot_id": "CL190_DROME", "id": "Q9VJE5-1", "name": "Restin homolog", "aln": "MSDDTSASGGTSAPFPSPVTADPEPGATASKLPGPIRSNIPTPATSGTGIPQPSKMKAPSSFGSTGSVSKIGRPCCNHTTPKSGPPPREATSMSRESDDNLSSINSAYTDNSSAVLTANTEQFIIGQRVWLGGTRPGQIAFIGDTHFAAGEWAGVVLDEPNGKNDGCVSGKRYFQCEPKRGIFSRLTRLTTYPLAG--------------AQTPTSPLAKSSPDRSRTVSPTASIRSSMLRSPGIGG-------------KNGMAVGDRVIVSSGFGSRPGILRYLGETQFAPGNWCGVELDEPSGKNDGTVDDIRYFECKPKYGVFVPIAKVSLSPSSKKTRLSRTGSRESLTSIGTMNSIATTATSRMRMNAQQRKSSTPVKPILATPKSQFSMQDLLREKQQHVEKLMVERDLDREDAQNQALQLQKNINELKARIVELESALDNERKKTEELQCSIDEAQFCGDELNAQSQVYKEKIHDLESKITKLVSATPSLQSILPPDLPSDDGALQEEIAKLQEKMTIQQKEVESRIAEQLEEEQRLRENVKYLNEQIATLQSELVSKDEALEKFSLSECGIENLRRELELLKEENEKQAQEAQAEFTRKLAEKSVEVLRLSSELQNLKATSDSLESERVNKTDECEILQTEVRMRDEQIRELNQQLDEVTTQLNVQKADS--SALDDMLRLQKEGTEEKSTLLEKTEKELVQSKEQAAKTLNDKEQLEKQISDLKQLAEQEKLVREMTENAINQIQLEKESIEQQLALKQNELEDFQKKQSESEVHLQEIKAQNTQKDFELVESGESLKKLQQQLEQKTLGHEKLQAALEELKKEKETIIKEKEQELQQLQSKSAESESALKVVQVQLEQLQQQAAASGEEGSKTVAKLHDEISQLKSQAEETQSELKSTQSNLEAKSKQLEAANGSLEEEAKKSGHLLEQITKLKSEVGETQAALSSCHTDVESKTKQLEAANAALEKVNKEYAESRAEASDLQDKVKEITDTLHAELQAERSSSSALHTKLSKFSDEIATGHKELTSKADAWSQEMLQKEKELQELRQQLQDSQDSQTKLKAEGERKEKSFEESIKNLQEEVTKAKTENLELSTGTQTTIKDLQERLEITNAELQHKEKMASEDAQKIADLKTLVEAIQVANANISATNAELSTVLEVLQAEKSETNHIFELFEMEADMNSERLIEKVTGIKEELKETHLQLDERQKKFEELEEKLKQAQQSEQKLQQESQTSKEKLTEIQQSLQELQDSVKQKEELVQNLEEKVRESSSIIEAQNTKLNESNVQLENKTSCLKETQDQLLESQKKEKQLQEEAAKLSGELQQVQEANGDIKDSLVKVEELVKVLEEKLQAATSQLDAQQATNKELQELLVKSQENEGNLQGESLAVTEKLQQLEQANGELKEALCQKENGLKELQGKLDESNTVLESQKKSHNEIQDKLEQAQQKERTLQEETSKLAEQLSQLKQANEELQKSLQQKQLLLEKGNEFDTQLAEYQKVIDEMDDAASVKSALLEQLQNRVAELETALRQANDAQKTAYLETKELRRQLESLELEKSREVLSLKAQMNGASSRSGKGDEVESLDIETSLAKINFLNSIIADMQQKNDALKAKVQTLETLPMDFTKPHAFDALTKRKPAPRLFCDICDEFDQHDTEDCPIQGSEDQDYSTPSSESNNNEKERKLPAPRKYCDSCEVFGHDTSECADDETY", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P33420-1", "uniprot_id": "NIP80_YEAST", "id": "P33420-1", "name": "Protein NIP100", "aln": "------------------------------------------------------------------------------------------------------------MRNAGVQVDTNMQKISLQDTVLVNEMK-GRVKFIGETQFAKGIWYGIELDKPLGKNDGSANGIRYFDIDLKK--------------------------------------ANSNGGYYGLFCKKDTLQFYKPDDD-----------------EHSLLNGN--------AAQETIKNLQVKCESLASKLNKIKIENHELKTSVEKLSTNETVLLSKISRLDKLVKELKVENGNMKTHLDNFNHLLDASDSVMAPDLDKGT---------------------LLERSHLLQGLLDQTKLSYDK---------------AMKVQEDLLEENTQLLEENAVLSKKISDLGLQLQQTNNTIGDLALQIEAQSKSSNIVDKLTNDNILLTSNIK----------------------------------ALNNELEELQAKEKLDENLRIT---------------------------YEQLEQELRLQLSNLQSALENEKEIAGTYIEEN--------------------------------SRLKATLESIEAKTSHKFQSL-------------------------------------------------------------ELKVNTLQEELYQNKLLKKFYQIYEPFAQPH-------------------------------------------------LAALSSQLQYLAEVIE--SENFGKLENIEIHIILKVLSSISYALHIYT------------IKNTPDHLETTLQCFKVNIAPISMWLSEFLQRKFSSKQETAFSICQFLEDNKFLDKDVT----------------------------------------------------------LILKILHPILETTVPKLLAFLRTNSNFND-----------------------------------NDTLCLIGSLYERSLSLIARIDKLIGKEE------------------------ISKQDNRLFLYPSCDITLSSILTILFSDALFLRQDYKRISSLKKLEVFFQGIESLLENITIFPE---------------------------------------------------------------------QPSQQTSDSESQCNIKEGNFSNSLLSDRLNEENIRLKEVLVQKENMLTELETKIKIIIGR---------------------DLERKTLEENIKTLKVELNNKNEENCGKTEILNKLK---------------------------------------------------------------EENFNLVNRLKNMELKLYQIKDNNTLNKIYLDREKVDRVNLVSEIMELRETIRRQIKEQKRVSID-----FSWLDELPAVEN------------------------KQPFKEHINHSLDTLGIEMFNFVSTSRILDLKLDQPLAEDELWHERDHSYISYLKRKRKNIRLKSQNVVTYYK-------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. .: : : * :. : * : ::*:*:*: * * *: *:. *****...* ***: : : : . : .:.: *: .:: : . : : .: ::::: *.. . . .* . : : * . . . .: . . : ..: .** :.. : : :*: : * : :: : : . : . :. .. . : ::*: :.: *::: :*.: * * : : .: : *: *: : : . : * :. :: :. ::. : * . : * : . . : : :: . .:. ::: : . . :: : * :: . . : . : : : : : : . :: . .* . : : : : : . * : : :. : ... . : . : . . : :.:.: : : : : : : : . * :: *. **: . . . . * :. : . . *:::. * : . .. : *:: :: : . . :: . . ::.: : : : . : . : . : . :. : ", "identical_positions": 47, "similar_positions": 246, "identity": "2.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100728-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A510-1", "uniprot_id": "D4A510_RAT", "id": "D4A510-1", "name": "", "aln": "MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQEEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRNVEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIVKRHQGTISEDKSNASHVVYPAPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAKWILDTDTFNEWMNEEDYEVSDDKSPVSRRKKISAKTLTDEVNSPDADRRDKKGGNYKKRKRSPSPSPTP---EAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKTVNTKKDSESAPVKGGTMTDLDEQDDESMETTGKDEDENSTGNKGEQTKSADLHEDNVTEQTHHIIVPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSGLVPLQPKPPQGRQVDADTKAGRKGKELDDLVPEAAKGKPELQGSASQQMLNFPDKGKEKPADMQNFGLRTDMYTKKNIPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVASAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTASDEPERIEESGTEEARA-ESQAADEKKEPKEPREGGGAVEEEAKEEISEAPKKDEEKGKEADSEKESEKSDGDPIVDPEKDKEPTEGQEEGLKEVAEPEGERKAKVERDIGEGNLSTAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMQQQPPPPPPPPPPPALPPGSQPIPPTGAAAPATVHGLAVAPASVASAPPGGGAPPGTLGPSEQIGQAGTTAGPQQPQQAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAGNAPLGLPFGLPLPPP-AAPSIIPFGSLADSISINLPPP-NLHG-HHHLPFAPGTIPPPNLPVSMANPLHPNLPATTTMPSSLPLGPGLGSAAAQSPAIVAAVQGSLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPPQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PDG5-1", "uniprot_id": "SMRC2_MOUSE", "id": "Q6PDG5-1", "name": "SWI/SNF complex subunit SMARCC2", "aln": "MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQEEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRNVEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIVKRHQGTISEDKSNASHVVYPVPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAKWILDTDTFNEWMNEEDYEVSDDKSPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRKRSPSPSPTP---EAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKTVNTKKDSESAPVKGGTMTDLDEQDDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQTHHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSGLVPLQPKPPQ-------------------------------QSSASQQMLNFPEKGKEKPADMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVASAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTASDEPERIEESGTEEARP-EGQAADEKKEPKEPREGGGAVEEEAKEEISEVPKKDEEKGKEGDSEKESEKSDGDPIVDPEKDKEPTEGQEEVLKEVAEPEGERKTKVERDIGEGNLSTAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQQP-----PTLPPGSQPIPPTGAAGPPTVHGLAVPPAAVASAPPGSGAPPGSLGPSEQIGQAGTTAGPQQPQQAGAPQPGAVPPGVPPPGPHGPSPFPNQPTPPSMMPGAVPGSGHPGVAGNAPLGLPFGMPPPPP-AAPSVIPFGSLADSISINLPPPPNLHGHHHHLPFAPGTIPPPNLPVSMANPLHPNLPATTTMPSSLPLGPGLGSAAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPPQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TAQ2-1", "uniprot_id": "SMRC2_HUMAN", "id": "Q8TAQ2-1", "name": "SWI/SNF complex subunit SMARCC2", "aln": "MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQEEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRNVEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYPVPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAKWILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRKRSPSPSPTP---EAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKTVNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQTHHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSGLVPLQPKTPQ-------------------------------QTSASQQMLNFPDKGKEKPTDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVASAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPERIEESGNDEARV-EGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPP-----PALPPGSQPIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAGNAPLGLPFGMPPPPPPPAPSIIPFGSLADSISINLPAPPNLHGHHHHLPFAPGTLPPPNLPVSMANPLHPNLPATTTMPSSLPLGPGLGSAAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPSPGTVTPVPPPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q5E9-1", "uniprot_id": "A0A8M9Q5E9_DANRE", "id": "A0A8M9Q5E9-1", "name": "", "aln": "MAVRKKDGGPNVKYFEASDTVSQFDNVRVWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQEEVFGRHVSNPPLTKLPVKCFLDFKAGGALCHILAAAYKFKSDQGWRRFDFQNPSRMDRNVEMFMTIEKSLVQNNCLSRPVIYLSSEIEPKLLGKLKDIIKRHQGSVTEDKLSSSHVVVPIPASLEDEEWVRPVMKRDKQMLLHWGYWPDSYDTWISASEVEAAVEDPPAAEKPRKVHAKWILDLDQFNEWMNEEDYEVGEGG---PRRKRISAKTLTDEVSAPD-ERRDKKPSGAKKRKRSPSPSPTPPPQESKKKNTKKGPTTPYTKSKRGQREEEQEDLTKELDEPSPVPAVEEATLPKTV-TKKDSDSTPVKGGTMTDLDEQEDESMETVGKEEEEGSPSVKGEPVKGSDLHEDNVTEQTHHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEYLTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDSESRPTPMGPPPTSHFHVLADTPSSLVPLQPKASQ--------------------------------TSSSQQMLSFPEKVKDKPADLQNFGLRTDVYSKKSGPAKNKNAASATREWTDQETLLLLEGLEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLEDSSASLGPLAYQPVPFSQAGNPVMSTVAFLASVVDPRVASAAAKSALEEFSRMKEEVPAALVEAHVRRVEEAARASGRQDPLYGLEGSGIAGTGLEDSDKPSDDGGEENKSSEGQPSQEKRDSKESKDG----ASEEEEKQGENGKKEEERAREVETERETEKTDS-EMADGEKEKERKEGSEEAQRD-GETEGEKKAKVERDVGEGNLATAAASALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLADRQSFHMEQLKYAEMRARQQHFQQIQHQHHSNQ---------PGSQ-----SATAPPVPH----QPVATASAPP--------------------------PTPSPAPLTATNTHSEAPPPPAAHSSPPN-----NTQAGAAHDSSTTPLAG-----------------------------------------------------------------DSLYP-------------------------------------------------------------TAPVPPSQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P43609-1", "uniprot_id": "RSC8_YEAST", "id": "P43609-1", "name": "Chromatin structure-remodeling complex protein RSC8", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSDTEKDKDVPMVDS-------------HEATEEPPTTSTNTPSFPHLA-------------------QEQAKEESATLGAEVAHKKINYEQEAQKLEEKALRFLAKQTHPVIIPSFASWFDISKIHEIEKRSNPDFFNDSSRFKTPKAYKDTRNFIINTYRLSPYEYLTITAVRRNVAMDVASIVKIHAFLEKWGLINYQIDPRTKPSLIGPSFTGHFQVVLDTPQGLKPFLP----------------------------------------ENVIKQEVEGGDGAEPQVKKEFPVNLTIKKNVYDSAQDFNALQDESRNSRQIHKVYICHTCGNESINVRYHN---------------------LRARDTNLCSRCFQEGHFGAN----FQSSDFIR-------LENNGNSVKKNWSDQEMLLLLEGIEMYEDQWEKIADHVG----------------------------------------GHKR------------VEDCIEKFLSLPIEDNYIREVVGSTLNG------------KGGDSRDGSVSGSKLMECVNDAVQTLLQGDD-----------KLGKVSDKSREISEKYIEESQAIIQELVKLTMEKLESKFTKLCDLETQLEMEKLKYVKESEKMLNDRLSLSKQILDLNKSLEELNVSKKLVLISEQVD--------------------SGIQLVE--------------------------------------KDQEGDDEDGNTATGHGVKRVGKEGE----------EVGEGDSIAKLQPQVYKPWSL---------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32591-1", "uniprot_id": "SWI3_YEAST", "id": "P32591-1", "name": "SWI/SNF complex subunit SWI3", "aln": "--------------------------------------------MENTLGEGSTVNASVDVDQHGNDNNSDSNANAAVAGVANTDTAGEESQQQDESLKDEATVPN------TRDAESEAITVTAKQQPTMQANKLDSQETPSTEESRAQNVFGQDNEDSDNLFGETESSVSNNEANTPSIPTNPVDNENNKPAIKEDSTIQDSNGDVKNMEDVKIQK---------------------------------------------------------------------EEEPENNTVIEGVKEESQPDENTKEMDEVEEDDEDDDQPMISPDNSIFGDTKSESKQLGNTSSVANTPSEIPDAHKAEQEDIIEKTESVDKKVDSGEERNEQEREIMN---DHSKSANPKKTTITRVEPETFEIPQAHEIVIPSYSKWFNLEKIHSIEVQSLPEFFTNRIPSKTPEVYMRYRNFMVNSYRLNPNEYFSVTTARRNVSGDAAALFRLHKFLTKWGLINYQVDSKLLPKNIEPPLTSQYSTRHDAPRGLFPFESYKPS------------------------------------VQLPDMAKLKKMMNTSDSESTLYKYLKESKRKYDEITHPPSTTDDENGDKNDNGGKMNNEVSTSTSMTGDAN--------------------LLEEGETSRPLKKVKILEQIDENWSKEDLQKLLKGIQEFGADWYKVAKNVGNKSPEQCILRFLQLPIEDKFLYGDGNGKGDNDNGLG----------------------------------------------------PLKYAPHLPFSKSENPVLSTIAFLVGLVNPKTVQSMTQRAIQSAESIKSQKEEISDQKPIEHIKEGSE----------IAISSLGYRSHIFATNEERQMNFLTNELIRLQMEKLDAKLNHLKKLEKFMELERKTLERQQENLLIQRLNFNQNSSKIVNVLSKCLNLISDSNINNSSVAE---------------KEEIRSQIDH---------------------------------------FKSMLSKPETLSIGKNPFNKPNIETGENHNGQSISNENDVKPISIEAPQFYRYWSA---------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .:. * .. : . . . . .: . :*: .:. . . . : *:* :::**:: **: ..:* ** :: *:**.. ***: * ***::::***.* **:: *: ***:: *..::.::* ** :*******:*.. *. : *. *.:: . *:* .* *: . :: . : : : .* . : : .. . . . *. .:. : . :: . : * : : : . * : ... : . . : : : : . :. . ::: :: .: : : *:. *:**: *: :: .**. :: *: : :::* :* : : . : . . . : . . . . ", "identical_positions": 64, "similar_positions": 154, "identity": "5.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100728-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7M2-1", "uniprot_id": "G3V7M2_RAT", "id": "G3V7M2-1", "name": "Integrin beta", "aln": "MVDSSTVLIFLLVLGGGQSELDTKITSSGETTEWEDPDLSPQGSCQPAPSCQKCILSHPSCAWCKQLNFTASGEAEARRCARREELLARGCPEQELEEPRGH-QEVLQDRPLSQGDRGEGATQLAPQRIRVTLRPGEPQKFRVRFLRAAGYPVDLYYLMDLSYSMKDDLERVRQLGQALLLRLREVTHSVRIGFGSFVDKTVLPFVSTVPSKLNHPCPSRLERCQAPFSYHHVLPLTRDAQAFEREVGRQNVSGNLDSPEGGFDAILQAALCQEQIGWRNVSR-LLVFTSDDTFHTAGDGKLGGIFMPSDGRCHLDSNGVYTNSAEFDYPSVGQVAQALTAANIQPIFAVTGATLPVYQELSQLIPKS-AVGELSEDSSNVVQLIMDAYDNLSSTVTLEHSSLPPGVSISFESHCRSPEKSEGEAGDRRGQCNHVRVNQMVDFWVTLQASHCLPE---AHVLRLWALGFSEELTVELHTLCDCNCSDAQ----PRAPYCSDGQGDLQCGICSCAPGRLGQLCECSEADL---SSPDLESGCRAPNGTG----PLCSGKGRCQCGRCSCSGQSSGRLCECDDASCERHEGILCGGFGHCQCGVCHCHANRTGRACECSESVDSCVSPEGGLCSGHGDCKCNRCQCLDGYYGALCDQCLG-CKSPCEQYRDCAECGAFGTGPL--AANCSAACADVNVTLALAPNLDDGWCKERT---------LDNQLFFFLVENSARG-VILRVRPQEKGADHTRAIILGCVGGIVAVGLGLVLAYRLSVEVYDRLEYSRFEKERQQLNWKQDSNPLYKSAVTTTVNPRFQGGNKQSLSLPLTQEAD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P26011-1", "uniprot_id": "ITB7_MOUSE", "id": "P26011-1", "name": "Integrin beta-7", "aln": "MVDSSTVLIFLLVLGGGQSELDTKITSSGEAAEWEDPDLSLQGSCQPVPSCQKCILSHPSCAWCKQLNFTASGEAEARRCARREELLARGCPAQELEEPRGR-QEVLQDKPLSQGDRGEGATQLAPQRIRVTLRPGEPQKFRVRFLRAAGYPVDLYYLMDLSYSMKDDLERVRQLGHALLVRLQEVTHSVRIGFGSFVDKTVLPFVSTVPSKLHHPCPSRLERCQPPFSFHHVLSLTGDAQAFEREVGRQNVSGNLDSPEGGFDAILQAALCQEQIGWRNVSR-LLVFTSDDTFHTAGDGKLGGIFMPSDGRCHLDSNGVYTNSAEFDYPSVGQVAQALTAANIQPIFAVTGATLPVYQELRQLIPKS-AVGELSEDSSNVVQLIMDAYDSLSSTVTLEHSPLPPGVSISFESHCKGPEKTEGEAGDR-GQCNDVRVNQTVDFWVTLQATHCLPE---AHVLRLWALGFSEELTVELHTVCDCNCGDAQ----PHAPYCSDGQGDLQCGICSCAPGRLGQLCECSEADL---SSPDLESGCRAPNGTG----PLCSGKGRCQCGRCSCSGQSSGRLCECDDASCERHEGILCGGFGHCQCGVCHCHANHTGRACECSKSVDSCVSPEGGLCSGHGYCKCNRCQCLDGYYGALCDQCLG-CKSPCEQYRDCAECGAFGTGPL--AANCSVVCADVNVTLTLAPNLDDGWCKERT---------IDNQLFFFLVEHAASG-IVLRVRPQEKGVDHTRAIILGCTGGIVAVGLGLVLAYRLSVEIYDRREYRRFEKEQQQLNWKQDNNPLYKSAITTTVNPRFQGTNGRSPSLSLTREAD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P26010-1", "uniprot_id": "ITB7_HUMAN", "id": "P26010-1", "name": "Integrin beta-7", "aln": "MVALPMVLVLLLVLSRGESELDAKIPSTGDATEWRNPHLSMLGSCQPAPSCQKCILSHPSCAWCKQLNFTASGEAEARRCARREELLARGCPLEELEEPRGQ-QEVLQDQPLSQGARGEGATQLAPQRVRVTLRPGEPQQLQVRFLRAEGYPVDLYYLMDLSYSMKDDLERVRQLGHALLVRLQEVTHSVRIGFGSFVDKTVLPFVSTVPSKLRHPCPTRLERCQSPFSFHHVLSLTGDAQAFEREVGRQSVSGNLDSPEGGFDAILQAALCQEQIGWRNVSR-LLVFTSDDTFHTAGDGKLGGIFMPSDGHCHLDSNGLYSRSTEFDYPSVGQVAQALSAANIQPIFAVTSAALPVYQELSKLIPKS-AVGELSEDSSNVVQLIMDAYNSLSSTVTLEHSSLPPGVHISYESQCEGPEKREGKAEDR-GQCNHVRINQTVTFWVSLQATHCLPE---PHLLRLRALGFSEELIVELHTLCDCNCSDTQ----PQAPHCSDGQGHLQCGVCSCAPGRLGRLCECSVAEL---SSPDLESGCRAPNGTG----PLCSGKGHCQCGRCSCSGQSSGHLCECDDASCERHEGILCGGFGRCQCGVCHCHANRTGRACECSGDMDSCISPEGGLCSGHGRCKCNRCQCLDGYYGALCDQCPG-CKTPCERHRDCAECGAFRTGPL--ATNCSTACAHTNVTLALAPILDDGWCKERT---------LDNQLFFFLVEDDARGTVVLRVRPQEKGADHTQAIVLGCVGGIVAVGLGLVLAYRLSVEIYDRREYSRFEKEQQQLNWKQDSNPLYKSAITTTINPRFQEADSPTL---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q931-1", "uniprot_id": "A0A8M9Q931_DANRE", "id": "A0A8M9Q931-1", "name": "Integrin beta", "aln": "--MMKAVLIALMVLLHCLG---------------QKYTLGEEPVCQNQPSCSECIRS-PGCAWCTQMNFLKSGESNERRCDSPKSLKDRGCEDVRVINPGKHPLDYVKNNDLSNDSYN--VVQLKPQNVNIKLRVGVPYEFTVEFKRAQGYPIDLYYLMDLSYSMQDDLEQIKTLGQKILKKLKDITETVRIGFGSFVDKEMLPYVSQLPPRRKNPCPNRINTCQKAFMFQNVLPLTSDGREFEREVSKQNISGNLDSPEAGLDAIMQAAVCKDKIKWGNVTR-ILVYTSDDTFHMAGDGRLGGAFLPHNGQCHFNDMGSYIG-KAYDYPSVGHVSRVLQDNNIQLIFAVTEEIYPAYKALSALIPQS-VVGVLKKDSSNVVDLISEAYGNLSSTLVLEQEGAPAELMVSYRSKCKD-NQAANEWREK-GECQGIKH-EKITFQVRLNATACLKE---PQIFRIKMQGISEEVKITVDTECQCDCGAAE----KSSEHCN-HKGDLSCGMCSCDEGYLGQNCSCVQQND---TIKMLDS-CR-PNNRS----LVCSGQGSCECGNCVCRNEYSGKYCECDPDSCEKRNGVRCNGKGKCECGKCECRDRYTGSACECSPSQDKCKN-DWGLCSGQGECVCNRCHCKP---GVIGDYCSA-FMDACELFKDCLACHLEGSG------SCHERCFNATVKHLEG-------THELS---------CIYKHVSYSVELKASGEVNVKYADLPHTVDKTAVIIGSSVSGIIITGIIIIIIYRLLLELYDYREYQSFVKMQNQTQWKEAQNPLFKGATTTVMNPLHMQNEA------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q27591-1", "uniprot_id": "ITBN_DROME", "id": "Q27591-1", "name": "Integrin beta-nu", "aln": "MTSLGGRAFLWIYLVFLIAEIS------------HSDADSIDDQCRHADSCERCLSAHLECAWCTDKEYQVG-----YRCLSRRQLLNYNCSETDIYE-NQPVLDVLQDKPLKDYETSDQAVQVTPQRAYLKLVKGNTQRMKLSYRTARNNPLDLYVLMDLTWTMRDDKKTLEELGAQLSQTLKNLTGNYRLGFGSFADKPTLPMI--LPQHRENPCAAERATCEPTYGYRHQLSLTDDIPAFTSAVANSKITGNLDNLEGGLDALMQVIVCTKEIGWKEQARKVVILVTDGFMHLAGDGLLAGIIQRNDKQCHLNKAGEYTGSLNYDYPSLEEIYRELLRRKINVIFAVTEEVVSSYWELSALMKEISYVDILSADSSNILELIKKSYESLIKRTQFADN-SPDFIDMAYYTDCGGQFPSLQ----KRNYCNNVTLGKQIDFYVDVTLKKYPDNQVYTHKIRVEETSLSEFMDLDVELQRPCPCQETPDPENEEGRFLCDYKGYLYCGMCECDEGWTGTYCNCPTDATNVTSNEALLQKCRQPFSDKSTSELVCSNHGDCDCGTCLCDPGYTGPFCECRECLDCDEK------LADCFCGQCVCKYGWSGSKCNCDGDTDACVGPTGEICSERGTCQCEECQCEEPYLGKFCEIDPEKDNKLCLFYEPCVTCLIEQKQGMGVCENLTEICSSLDRQETYPYNFVHELDPEQDQCLVRLVNKHGIQCDSFFVYQVIDHSNFLTIQAVDCEPPDYVALVGYISAFTLLIGLLIIFIILWYIRAKDAREYAKFEEDQKNSVRQE--NPIYRDPVGRYEVPKALSVKYDENPFAS-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * . .. . *: **..*: : ****.: :: . ** ..* .* : : : :::. *.: . ..*: **. :.* * . .: : : * . *:*** ****:::*:** : :. ** : *:::* . *:*****.** ** : :* : .:**. . *: .: ::: *.** * * *....::****. *.*:**::*. :* .:* * : :* ::: .:*. :* **** *.* : : :**::. * * :****: .: : * :*: ***** . * * *: : *. *. ****:::** .:* .* . : .. * : ::: :.* . : . *: : : : * * : . : .: :*: .:** : : :. * * : . . :* * **:*.* * * *.* : * . ** * . :**.:* *:** * * :* *** .: . * ** * *: :* *:*. . * * . :** :* * *:.*:* * : : * .. * * . . * * : : * : . .:: . : *: ::: :. * ** * : ::: :: **:::.. * . ", "identical_positions": 172, "similar_positions": 211, "identity": "20.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100728-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q10468-1", "uniprot_id": "B4GN1_RAT", "id": "Q10468-1", "name": "Beta-1,4 N-acetylgalactosaminyltransferase 1", "aln": "MRLDRRALYALVLLLACASLGLLYASTRDAPGLPNPLALWSPPQGPPRLDLLDLAT---EPRYAHIPVRIKEQVVGLLAQNNCSCESSGGRFALPFLR----QVRAIDFTKAFDAEELRAVSISREQEYQAFLARSRSLADQLLIAPANSPLQYPLQGVEVQPLRSILVPGLSLQEASVQEIYQVNLIASLGTWDVAGEVTGVTLTGEGQSDLTLASPILDKLNRQLQLVTYSSRSYQANTADTVRFSTKGHEVAFTILIRHPPNPRLYPPSSLPQGAQYNISALVTVATKTFLRYDRLRALIASIRRFYPTVTIVIADDSDKPERISDPHVEHYFMPFGKGWFAGRNLAVSQVTTKYVLWVDDDFVFTARTRLEKLVDVLERTPLDLVGGAVREISGYATTYRQLLSVEPGAPGFGNCLRQKQGFHHELAGFPNCVVTDGVVNFFLARTDKVRQVGFDPRLNRVAHLEFFLDGLGSLRVGSCSDVVVDHASKVKLPWTSKDPGAELYARYRYPGSLDQSQVAKHRLLFFKHRLQCMTAE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q09200-1", "uniprot_id": "B4GN1_MOUSE", "id": "Q09200-1", "name": "Beta-1,4 N-acetylgalactosaminyltransferase 1", "aln": "MRLDRRALYALVLLLACASLGLLYSSTRNAPSLPNPLALWSPPQGPPRLDLLDLAP---EPRYAHIPVRIKEQVVGLLAQNNCSCESKGGSLPLPFLR----QVRAVDLTKAFDAEELRAVSVAREQEYQAFLARSRSLADQLLIAPANSPLQYPLQGVEVQPLRSILVPGLSLQEASVQEIYQVNLSASLGTWDVAGEVTGVTLTGEGQPDLTLASPVLDKLNRQLQLVTYSSRSYQANTADTVRFSTKGHEVAFTILVRHPPNPRLYPPSSLPQGAEYNISALVTIATKTFLRYDRLRTLIASIRRFYPTVTIVIADDSDKPERISDPHVEHYFMPFGKGWFAGRNLAVSQVTTKYVLWVDDDFVFTARTRLEKLVDVLEKTPLDLVGGAVREISGYATTYRQLLSVEPGAPGLGNCFRQKQGFHHELVGFPSCVVTDGVVNFFLARTDKVRQVGFDPRLNRVAHLEFFLDGLGFLRVGSCSDVVVDHASKVKLPWTAKDPGAETYARYRYPGSLDQSQVAKHRLLFFKHRLQCMTAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00973-1", "uniprot_id": "B4GN1_HUMAN", "id": "Q00973-1", "name": "Beta-1,4 N-acetylgalactosaminyltransferase 1", "aln": "MWLGRRALCALVLLLACASLGLLYASTRDAPGLRLPLAPWAPPQSPRRPELPDLAP---EPRYAHIPVRIKEQVVGLLAWNNCSCESSGGGLPLPFQK----QVRAIDLTKAFDPAELRAASATREQEFQAFLSRSQSPADQLLIAPANSPLQYPLQGVEVQPLRSILVPGLSLQAASGQEVYQVNLTASLGTWDVAGEVTGVTLTGEGQADLTLVSPGLDQLNRQLQLVTYSSRSYQTNTADTVRFSTEGHEAAFTIRIRHPPNPRLYPPGSLPQGAQYNISALVTIATKTFLRYDRLRALITSIRRFYPTVTVVIADDSDKPERVSGPYVEHYLMPFGKGWFAGRNLAVSQVTTKYVLWVDDDFVFTARTRLERLVDVLERTPLDLVGGAVREISGFATTYRQLLSVEPGAPGLGNCLRQRRGFHHELVGFPGCVVTDGVVNFFLARTDKVREVGFDPRLSRVAHLEFFLDGLGSLRVGSCSDVVVDHASKLKLPWTSRDAGAETYARYRYPGSLDESQMAKHRLLFFKHRLQCMTSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BDH6-1", "uniprot_id": "A0A8M2BDH6_DANRE", "id": "A0A8M2BDH6-1", "name": "Beta-1,4 N-acetylgalactosaminyltransferase", "aln": "----MRSLRKTVLLALVASVVLVLAVLHSWPTRVYSTVDVRYRPGPGAERLLEERLPELDPSASTIPYRVRESVARLLARNGCVCEGESRGVNLPFAQLLFPRVSAHPLHTAFQASQLDEMKKRRAKEYQSFQMRSQTPADLLIVAEANNPLQYPTQGVEVRPLKTILIPGLALKELP-RDVYTLNFSASLGTFNVAAEVEGVKVRGDGEMHMTLSSSVLSSLNRQLQFITYTNTLFHPSTADTVQLDTEGHQALFTIKIRHGVTPKLYNTGSDAD-KEYNISALVTIATKTFLRYDKLQNLIDSIRQYYPTVTIVIADDSEHPKTVSGPYIEHYIMPFGKGWFAGRNLAVSQVTTKYVLWVDDDFIFSANTKLEKLVDVLEKTTLDLVGGAVREATGYTATYRQTISIEAGEE-DGDCLHMRRGFHHIIQGFPHCVITDGVINFFLARTDKVQQVGFDPRLARVAHLEFFIDGLGSLHVGSCDDVIVNHATKIKLPWGQSES-DKTYAKFRYPPASSDATHTKNGLLYFKNRFQCLTHN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:* *** **: *: : :. * . . .* * : :* : ** *::*.*. *** *.* **... . *** : :* * : .**:. :* . * :*:*:* **:: ** *::* **.***** *****:**::**:***:*: . :::* :*: *****::**.** **.: *:*: .:** *. *..******::**:. ::..*****::.*:**:. *** :** .*:** ..* .: :********:*********:*: ** ***::*****:******::*: :*.*::***:******************************:*:*.*:**:******:*.********** :*:::**** :*:*.* *:*:: ::**** : *** **:****:**********::******* ********:**** *:****.**:*:**:*:**** :. : **::*** : .:: :*: **:**:*:**:* :", "identical_positions": 279, "similar_positions": 144, "identity": "51.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100728-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P720-1", "uniprot_id": "ARHGP_RAT", "id": "Q6P720-1", "name": "Rho guanine nucleotide exchange factor 25", "aln": "MKPPDRPTPGRTDRILGVMGGMLRACAVPGQEGPQERDPLGPGSTKTESECTEE----------DQTGEREREVLAWAPQPESYSIAGSEGSMSASAVSGLAALSGPSSGLSSHPCSPVPPGPVTGLRRWLDHSKHCLSVETEADS---GQTRQCENWMLEPTLTTGQELP--------ELTLLT--------------------TLLEGPGVKAQPA----------------------------EEETLSQAPKNEEEQKKTALERSMFVLSELVETERMYVDDLGQIVEGYMATMATQGVPESLRGR--DRIVFGNIQQIYEWHRDYFLQELQQCLKDPDWLAQLFIKHERR--LHMYVVYCQNKPKSEHVLSEFGDSYFEELRQQLGHRLQLSDLLIKPVQRIMKYQLLLKDFLKYYRRAGMDTEELEQAVEVMCFVPKRCNDMMSLGRLRGFEGKLTAQGKLLGQDTFLVTEPEAGGLLSSRGRERRVFLFEQIVIFSEALGGGGRGGTQPGYVYKNSIK----------------------------------ASDPAVSQAWIKQVAQILESQRDFLNALQSPIEYQRRESQTNSLGRSGGPGVGSPGRM-----AQVSMHTP-----INGSLPSLLLLPRG---------------------------------EVPRAPLPLDTQALS-----------------ETPLTPYDPP-ALPTVNSPPGQ-ARLAKLDEDEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWR0-1", "uniprot_id": "ARHGP_MOUSE", "id": "Q9CWR0-1", "name": "Rho guanine nucleotide exchange factor 25", "aln": "MKPPDRPTPGRTDRILGVMGGMLRACAVPGQEGPPERDPLGPGSTKTESDCIEE----------DQTGQREPEVLAWAPQPESYSIAVSEGSMSASAVSGLAALSGPSSGLSSDPCSPIPPGPVTGLRRWLDHSKHCLSVETEAES---GQTGQCENWTLGPTLTTGQELP--------ELTLLT--------------------TLLEGPGDKAQPA----------------------------EEETLSQAPKNEEEQKKMALERSMFVLGELVETERTYEDDLGQIVEGYMATMATQGVPESLRGR--DRIVFGNIQQIYEWHRDYFLQELQQCLKDPDWLAQLFIKHERR--LHMYVVYCQNKPKSEHVLSEFGDSYFEELRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYRRAGKDTEELEQAVEVMCFVPKRCNDMMSLGRLRGFEGKLTAQGKLLGQDTFLVTEPEAGGLLSSRGRERRVFLFEQIIIFSEALGGGGRGGAQPGYVYKNSIKVSCLGLEGNLQGNPCRFALTSRGPEGGIQRYVLQASDPAVSQAWIKQVAQILESQRDFLNALQSPIEYQRRESQTNSLGRPGGPWVGSPGRMRPGDLAQASMHTP-----INGSLPSLLLLPRG---------------------------------EVSRVLLPLDTQALS-----------------DTPQTPHDSP-ALPTVNTPPCQ-ARLAKLDEDEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86VW2-1", "uniprot_id": "ARHGP_HUMAN", "id": "Q86VW2-1", "name": "Rho guanine nucleotide exchange factor 25", "aln": "MRG-------------GHKGG---RCACPRVIR------------KVLAKCGCC----------FARGGRE-----------SYSIAGSEGSISASAASGLAAPSGPSSGLSSGPCSPGPPGPVSGLRRWLDHSKHCLSVETEADS---GQAGPYENWMLEPALATGEELP--------ELTLLT--------------------TLLEGPGDKTQPP----------------------------EEETLSQAPESEEEQKKKALERSMYVLSELVETEKMYVDDLGQIVEGYMATMAAQGVPESLRGR--DRIVFGNIQQIYEWHRDYFLQELQRCLKDPDWLAQLFIKHERR--LHMYVVYCQNKPKSEHVVSEFGDSYFEELRQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFLKYYNRAGMDTADLEQAVEVMCFVPKRCNDMMTLGRLRGFEGKLTAQGKLLGQDTFWVTEPEAGGLLSSRGRERRVFLFEQIIIFSEALGGGVRGGTQPGYVYKNSIKVSCLGLEGNLQGDPCRFALTSRGPEGGIQRYVLQAADPAISQAWIKHVAQILESQRDFLNALQSPIEYQRRESQTNSLGRPRGPGVGSPGRIQLGDQAQGSTHTP-----INGSLPSLLLSPKG---------------------------------EVARALLPLDKQALG-----------------DIPQAPHDSPPVSPTPKTPPCQ-ARLAKLDEDEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AYL2-1", "uniprot_id": "A0A8M3AYL2_DANRE", "id": "A0A8M3AYL2-1", "name": "Rho guanine nucleotide exchange factor 25", "aln": "MKSLPK-NQGRTDEILGAMADMLTSLAIPNQKWNS--DSIEHLSVKQERKTSQRPPWDTEGLNWEDMSRDSLERVRRRDRANSYSAAGSEGSISTSVASLPPQASG-----SSAPNSPGSRRSVSTLKKWLTNPVRKLSAGAAGSAKGERQVRRLEGKPPPPPTRSSQELG-SPQSTEEQFTILPGIDKELEWKDGLPALGDCDPGLLQSYSFQSDSPQGSTTLGQTQISQCTSQQADDNGSVLMDDNSSQSSACADTEEDRKSALEKSMYVLNELIETEKLYVADLGLIVEGYMATMNVKGIPEDMKGK--DKIVFGNIHQIYDWHKDYFLAELEKCVAEPERLAQLFIKHERR--LHMYVVYCQNKPKSEHIVSEYIETYFEELKQQLGHRLQLNDLLIKPVQRIMKYQLLLKDFHKYYTKAGMDTEELEKAVEVMCFVPKRCNDMMNVGRLQGFEGKITAQGKLLQQDTFTITEQDSS--ILSRAKERRVFLFEQLVIFSEPIDRK-KGFSLPGYIFKNSIKISCLGVEACVDGDPNRFALTSRGADGSTVRYVLYSSSPDICMAWVSDVSQILETQRNFLNALQSPIEYQRRESKSNSLGRSIKPPLSAVAGLRPHSSASIDRHKLPCLRSCNTSLPSLYLPSQVPTDDHSQPESTPVDSRLNSQTVSPTHVQLAFSEEPSFSQAPLNCQAVSNGLYSSSTQGSQISGEGGRRVSQRECRMSVPSPSSTLQRSSNLAQLDEDDL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZAQ4-1", "uniprot_id": "A1ZAQ4_DROME", "id": "A1ZAQ4-1", "name": "DH domain-containing protein", "aln": "------------MELSLFTLNLFDVVSVVLTFLVIFLVQILNVYLHILDDNADN-----------------------------GKSIDVVDKAPAKECPLLESQSPSSPIATTLPKSQASSNGKLEKQISLLDSDSGISLSSINTC----STTAANSSPTYRAPNGFHSFPS--HTLS-----------------------------FETLGDEYHED----------------------------EDTLSLENLFPCDQTEIYASKKISFIIDELIQTEVNYVNNLKKGMLNYGQLKDVEDLPEALSGETKQKMLLGNIKEILELHEKEILPLMLRNQRDLKGLFDEFAAHFEKNSFYCYVSFTMGK-KSSMQLRQDNRLWLQTYQTQIKDKLGIDSFLVQPIQRLTRYPLLLQQFISEFYKSGISCKPVLTAVCKLETRMRRALDVVNQAEEIPNIEELNELDVLQLGNFRRATEFDAQHFPTRKKYRSKVFLFDRCLVCTEVRKKRLAYRQHYNWEHVELQR------------------------------------PLDSVSSNANKIINLLVKQEEGGSSVGSKREEYSFMAAEASVVKQWLQATHKIIEIARNEHARRNTFSLPMDLVLGVVLAIWLIWQYL---------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . . .. .:. . * :: * * . : * .. :* : . .. :. . ..: :: . : . :: . :: . * :: :::.**::** * :* : .* .:.:** : *. :::::***::* : *.. :* : : : . * : * * .: :: ** : .* **. : : ::: : *: .:* :..:*::*:**: :* ***::* . : ::* . : ** : :*. *::. .. ::. . * : ** :: : . :****:: :: :* .: . : : : ..: ::* .*.: .:: * * : *: : : * . .. . *. : ", "identical_positions": 61, "similar_positions": 155, "identity": "8.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100728-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A4S8-1", "uniprot_id": "A0A8I6A4S8_RAT", "id": "A0A8I6A4S8-1", "name": "", "aln": "--------------------------------------------------------MPILKSLG----------------------------------VGDPKVPRAGTLPLRSSRNPFEETPTLEEEDG-ELGTLPNGTSCRR---RATLEK---LAGLAPFRLGWTSGR--RAGSPGDR-QVRSFLGRVLAPG------IRRSSADFGLLNRLQGFRTHGD---------EEPAGEAARRLAFLRLGRGPKPRRASLAERLVPAGEAAPEPPPKVPEPPKIKEPLSVLEILGLIQRRELARADEHILELEAEAP---------------AEAEAGAGRRARDVALLYEALQRELWALVRESLAAPGP----GTGAVAQLGLVLLQEEEAD--------ARRGPGAARKLRAHWAEAVARAARERLEEAAAPGARGTLSGQLEALRARLLEDVAAVRGRLAPAYPAGLRAGAVYLRGYHEALAEWLGAAARRR---LPLADRYALLHWHNQVYPREILGLVDVVALEN-GELGPLLSAGTLRGLEDECVTDVKAQTRAALLRVLQEDEEQWG---SMDYRPSNLAQDVCELLEEHTERAP---------HISQEFVERMAYCCLGGLAEFLQSFQQRVERFHENPGVRELPS------DTYISRTISMVN--------CGPPLRSLAERLARVGPPESEPAREASAIALDRVTRLCHRVLAELLFQELQPHFNKLMRRKWLSSSEALDGIVGTLGAQALALR-RMQDEPYQVLVAELHRRALVEYVRPLLRGRLRCRSARTRSRMAGRLREDAAQLQRLFRRLESQAYWLDQVVPHLAEILQLEDTPSIQVEVGVLVRDYPDIRRKHVAALLDIRGLRNTAARQEILAVARDLELSEGGALSPSRDRAFFADIPVPRTSFCLGLPLFLGRLPVSRLARPNLACLPLRPRPPSPVRARADR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YUP5-1", "uniprot_id": "D3YUP5_MOUSE", "id": "D3YUP5-1", "name": "", "aln": "--------------------------------------------------------MPILKSLG----------------------------------VGDPKVPRAGTLPLRSSRNPFEDTPTLEEEDA-ELGTLPNGTSCRR---RATLEK---LAGLAPFRLGWTSGR--RAGSPGDG-QVRSFLGRVLAPG------IRRSSADFGLLNRLQGFRTHGD---------EEPAGEAARRLAFLRLGRGPKPRRASLAERLVPAGEAAPEPPPKVPEPPKIKEPLSVLEILGLIQRRELARADEHILELEAEAPT--------------AEAEAGAGRRARDVALLYEALQRELWALVRESLASPGP----GTGAVSQLGLVLLQEEAAD--------ARRGPGAARKLRTHWAEAVARAARERLEEAAAPGARGALAGQLEALRARLLEDVAAVRGRLAPAYPAGLRAGAVYLRGYHEALAEWLGAAARRR---LPLADRYALLHWHNHVYPREILGLVDLVALEN-GELGPLLSAGTLRGLEDECVTDVKAQTRAALLRVLQEDEEQWG---SMDYRPSNLAQDVCELLEEHTERAP---------HISQEFVERMAYCCLGGLAEFLQSFQQRVERFHENPGIRELPS------DTYISRTISMVN--------CGPPLRSLAERLARVGPPESEPAREASAIALDRVTRLCHRVLAELLFQELQPHFNKLMRRKWLSSSEALDGIVGTLGAQALALR-RMQDEPYQVLVAELHRRALVEYVRPLLRGRLRCRSARTRSRVAGRLREDAAQLQRLFRRLESQAYWLDQVVPHLAEILQLEDTPSIQVEVGVLVRDYPDIRRKHVAALLDIRGLRNTAARQEILAVARDLELSESGALPPSRDRAFFADIPVPRTSFCLGLPLLLGRLPVSRLARPNLACLPLRPRPPSPVRARADR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2M3D2-1", "uniprot_id": "EX3L2_HUMAN", "id": "Q2M3D2-1", "name": "Exocyst complex component 3-like protein 2", "aln": "--------------------------------------------------------MPILKNLG----------------------------------VSDPKVPRAGTLPLRSSRNPFEEVSGLEEEEAGELGSLPNGTSCRR---RATLEK---LAGLAPFRLGWAPGR--RAGSPGDG-QPRSFLGRVLVPG------IRRSSADFGLLARLHGTRAHGD---------EEAAGEAARRLAFLRLGRGSKPQRASLAERVVPAGEAAPEPPPKVPEPPKMKEPLSVLEILSLIQQRELARADEHILELEAEELAPSRGGA----PGPPKAEGAGGGRRARDVALLYEALQRELWALVRETLAGPGPGACAGAGAVAQLGQVLVQEEAAD--------GRRGPGAARKLRARWAEAVARAARERL-EAAAPGAPGGLAGQLEALRARLLEDMAVVRGRLAPAYPAGLGAFGVYLRGYHGALAEWLGASARRR---LPLADRYALLHWHNQVYPREVLGLVDMAALEN-GELGPLLSPGTLRGLEDECVTDVKAQTRAALLRVLQEDEEHWG---SLEDQPSSLAQDVCELLEEHTERAP---------RISQEFGERMAHCCLGGLAEFLQSFQQRVERFHENPAVREMLP------DTYISKTIALVN--------CGPPLRALAERLARVGPPESEPAREASASALDHVTRLCHRVVANLLFQELQPHFNKLMRRKWLSSPEALDGIVGTLGAQALALR-RMQDEPYQALVAELHRRALVEYVRPLLRGRLRCSSARTRSRVAGRLREDAAQLQRLFRRLESQASWLDAVVPHLAEVMQLEDTPSIQVEVGVLVRDYPDIRQKHVAALLDIRGLRNTAARQEILAVARDLELSEEGALSPPRDRAFFADIPVPRPSFCLSLPLFLGRLPLSRLARPSLACLP-RPRPPSLARPRAQR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q5H9-1", "uniprot_id": "A0A8M9Q5H9_DANRE", "id": "A0A8M9Q5H9-1", "name": "", "aln": "MYGQLLSESDTYCLTNQHKNTHRYKVAGTLGCPCSETFRDLPSLCCQTSIHPPSATMPVLKNLPSRLKGGRFSVDLETTRSEFILRKMSLNHNPFEEPGSDEDWPRSNGGSLLDGRVPRDRNPFEDEEDENEANEVRRGGSGKGGSIKGTLER---MKGVSPLKTLGKLGKNLRLSSRSKGRETPSPQGSIGSASPMERKKKGRRSSEGSLLRMAGRCKDRKESLTNGELCSETDADSTSRRLSFLKMVGKGKMKRESLQDHSSQG--PEEEPVEEVPEV-KPREPLSVLEILQLVTKRDLFLADTHILELEQECREAESPTAGGTEDFSSPSSKDSSRRKAKDVELLYEALQKELWDVVRDSLRCPTAG-----PNLGLVVQVLQQEEQADRDWAQSEGAAPGGPRPREFRKRWKEAVVELADANLPQHAEARA-GELATFLDKLRVRMVEDLGAARRNAVSVYPAEYDSFQVYTQSYHQAVTRRLQALTNGD---LQITDIYSLLDWLYNIYNRDVLGTVTITTPINLSQLGPLLPTETVDKLELDCLNSVRGKVTNELSQVLEEEEKRWLDTLNIEEYQIPLARTVIQRLQEDLERSA---------AVNRHLGSRVAQCSLNGLADFLYSFQRKVEMFHEMLVSSFGENE-----DGYIAKTIALAN--------CCPSFRSFVQRCGQCDPSTSEDSIRRANSALDRIVNLSVRVLNDRLFEHIRPFFDKLIKRKWLSNTEPFEQIEALIKEHFKKFR-RMDNPPYEVLVVEVHRRVMTEYVRAIMRGRIICTSLKMRKRMAGRLRDEGKHLKTLFKELESSASWLDSAIPHLSEIILLEDTPSIQMEVGVLVREFPDIRRKHVSAILNIRGMTRQTERQEILNIVKDIENSDSVAR-VSRDRALFAEVPVTSEVHCLNLGLSRVALTAS-----NLFSSMRRRRTPTRENHDDVL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32844-1", "uniprot_id": "SEC6_YEAST", "id": "P32844-1", "name": "Exocyst complex component SEC6", "aln": "----------------------------------------------------------------------------------------------------MSSDPLQQVCDLIKGDLSLERVRDIKEQLLKEKSVVEYQLNKESDKYYGEVEESLKLLNLSKNSVTSIKQQINEVNKLGNDNRFAINRYDILFRATKLYETVNTTSSIYDRIYNFVALMEHIER----LLVAELAEDALETGCPHLLEIHFLLTSARDFQEQVVVMAKEATEDAQRTVMKLFSRLSGIISKFDKLLDGLTYDIVEMARAEQISLAIR-------------LFKIYDLEEREDLRIEAIRNIIKKKEIEIEKSSIKKLPNSK-NTARLQDETPKVIEYPTNKGLYQEIMSGTISTRTAPRGYKHFLINGINNSISEMFGEMREKYVGDQKFDVLDNM-DWIFNELIIVKEHIANCCPPHWNIFEVYFDQYYKELHSLITDLVESEPETIIILDILAFDKTFQDTLKQDFGFTKSEVKSVIGDKEKETLFKDYLNLIVVKMTEWIGNLEKAEFDVFLERSTPPHSD--SDGLLFLDGTKTCFQMFTQQVEVAAGTNQAKILVGVVERFSDLLTKRQKNWISKISEEIKKQINYNHKYDIDPESITPEDECPGGLVEYLIAVSNDQMKAADYAVAISSKYGKLVSKVYEKQITNHLEGTLDGFAEVAQCSSLGLITLMFDDLRKPYQEIFSKTWYMGS-QAQQIADTLDEYLLDIKPQMNSVLFVNFIDNVIGETIIKFLTALS---FEHSFKNKNNKFLEAMKRDFEIFYQLFVKVLDGNESKDTLITQNFTVMEFFMDLSCEP-----IDSILDIWQKYLEVYWDSR----IDLLVGILKCRKDVSSSERKKIVQQATEMLHEYRRNMEANGVDREPTLMRRFVLEFEKQ----------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * * .. . : .*: * . : . . . :*. : .:: : . .. .. . : . *: . : : : * . ..* .: :: * .. : . : :: *: .: * *. : : : :::: : :.:: *: . .* : :.: . : : . . *: : :.::: .: . . *. ** *: : : .. : : * :: . . ::. . .: * : : . : : .*:.. . :: : : :. * :. : ..: . :: . ::.: .:::::: *: . : *:: * . . : .: . : .: .:.. . : :*:.:: ::::: :.* .. : * : :: :*:. : :: :: ..: ::: .: : . ..:. :: : : ** .: . * :.: :: : * : : . ** :*:: . : * ** :*:. *: . :. : . ", "identical_positions": 42, "similar_positions": 230, "identity": "4.37%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100729-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7Z3H0-2", "uniprot_id": "PANKY_HUMAN", "id": "Q7Z3H0-2", "name": "Photoreceptor ankyrin repeat protein", "aln": "MKVQPSVTCVASWGGIVHLEAFGDPVIVLRGAWAVPRVDCLIDTLRTPNASCMRKGTHLLVPCLEEEELALHRRRLDMSEALPCPGKETPTPGCRLGALYWACVHNDPTQLQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNR----------CADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQLLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQV--APSLLERLQATLSLPFAPSPQEGGVLDHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELLGTAPPPPLVPQ-------------SPPGSPQRSPWVFVPYQSPQG-ILSKCLQWLQP------RDSTSPRPQVPKILLSKASSSSHQCQPKPSPSGHQSLALPLWRYQELRIEKRKQEEEAR---MAQK-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BXP5-1", "uniprot_id": "PANKY_MOUSE", "id": "Q8BXP5-1", "name": "Photoreceptor ankyrin repeat protein", "aln": "-----------------------------------------------------------------------------MSEALPFPSNKTSTPECNLKTLYWACVHNDLAELQARLDAGVSPEEASQVDSNGRTGLMVACYHGFGSIVALLSCCPFLDVNQQDKDGNTALMLAAQAGHMSLVTLLLNYFAGLDLERRDQRGLTALMKAAIQDRSECVVALLMAGADLSSVDPVRGKTALEWAVLTDSFDTAQKIRQLLRRPQAEQLSLHYQPEWPALAQLVAQAQAQAQAPAAPSLLERLQATLSLSFAQSPQEGGVLDHLVTVTTSLASPFLSTACHTLCPDHPPKLGTRGKSVPELLGTAPPPPPEPH-------------PPQQVP--VPQVFAPNQSPQS-MFS---QWLQS------RDST--RSQVPKILLSKAPSPSARYELTLRPQGQQSLAPPVWRFQER--KKKEEETEPRGGGLGQAGGSK---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8N7URE1-1", "uniprot_id": "A0A8N7URE1_DANRE", "id": "A0A8N7URE1-1", "name": "", "aln": "-----------------------------------------MAAVQSSGFEDPHLGSCPDGDEISLLDEDTDSGSLLSEDSVLPEYELEDGKKGTANTLYEACVQNDPEALKRILERGVTCDEVMEVDINGWNGLMVAAYKGFLQIVYELHGCPHLNINHQDNDGNTALMIAAQAGHVSICNYIMNYFPGADTEIRDNRGFTALIKAAIQGRNDVVAALIMHGADVNAVDSNRGKCARDWALKTGRFDTLKRLRHLALHPTAEQFCDTYVPEWPNLKVLVSKATANRSAG--QKLTHHLKNRFGFSFPRDPVENGVMDHMVRMTTSLHSPLIATATRPLCPSSPPQMGKRRLAVAELMQKHSEKLLEESSLCHRNSSISSVSPSFHSAEFVSMTCCPDTERRGSVLSIGMRTFIPRSVASRRNSIFPSGCIPQIKVTKSSEPTPKKEKK-NKKDKGYLEPPKWKYKEAKEEKKKEKKALKEKEKEEKDKEKKSKDKEKRKKNKYTD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::: : :** ***:** *: *: **: :*. :** ** .*****.*:** .:* * **.*::*:**:.*:****:******:.: . ::**: * * * **:**:***:***::.* **:.:**. *** * :**: *. *** ::*:* :* .**:. * **** * **::* *: .. .* .:*: :.:.*. .* *.**:**:* **** **:::** :.***. **.:*.* :*.**: . . .. . . . * . :. ::* : : . *:* :*:* ::*:...: : : . ..: * * *:::* :*:::: : : ", "identical_positions": 128, "similar_positions": 124, "identity": "25.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100729-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A7G2-1", "uniprot_id": "A0A8I6A7G2_RAT", "id": "A0A8I6A7G2-1", "name": "", "aln": "---------------------------------------------------------MLLFVE-VTSKGTGLNPNAKVW-QEIPSGNPDGTPVT---------ETSWHETAATSGSHPEGNTELS------EEMCKEYEVMYSPSCEPTRNTADIEESADG---------------MILGPE--DLSYQLYD-VSGESS---------------------------------------------------------------STISTEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLILEVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETTPVEEVKALFKNENCPKVISCEFAHNSNWYITFQSDTDAQQAFKYLREEVKTFQGKPIMARIKAINTF-----FAKNGYRLMDSSMYTQPIQT------------------------PTQYPSPVFMQPVYNPHQQYSVYS-IVPQSWSP-------------------------------------SPAPYFETPLAPFPNG--------------------------------------------------------------------------------------------------------------------------------SFVNGFSSPGSYKTNAAAMNMGRPFQKNRVKPHFR----------SSSGSEHSTDGSVSLGDGPVSRSSSRIFLSERHNPTVTGHQEQTYLPKDAPILQMEQNGD-----FGRGRRTLFRG--------------------------RRRREDDR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IPRPQPAATEAKAPAPKFDLLATNFPPLPG------SSSRMPDELALEN----------------------------------------------------------------------RMSDVVKG----------------------------------------------------VCKEKDNEDLRVSCPVPAEDGQTDCASVPQLSISPSPPCTAEPPALSSTTQQEKDQMEDS------------------------------------------AAPKDVLNPVPVPVSSPTTTKPS----------------RANTASPCNSTVNTPIAVAPQEPRKLSYAEVCQKPPKEPSPVLVQPLRELRSNVVSPTR-------NEENGAPEKPVE--KPQEKPETRASKDHSG-------------------------------FRGNTIPRGAAGKIREQRRQ--FSHRAAPQ-GVTRRNGKEQYVPPRSPK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BWW4-1", "uniprot_id": "LARP4_MOUSE", "id": "Q8BWW4-1", "name": "La-related protein 4", "aln": "---------------------------------------------------------MLLFVE-VTSKGTGLNPNAKVW-QEIPSGNPDGTPVT---------EPSWHETAATSGSHPEGHTELS------EDMCKEYEVMYSPSCETTRNTADVEESADG---------------MILGPE--DLSYQLYD-VSGESS---------------------------------------------------------------SAISTEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFVPIWTVANMEEIKKLTTNTDLILEVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETTPVEEVKALFKNENCPKVISCEFAHNSNWYITFQSDTDAQQAFKYLREEVKTFQGKPIMARIKAINTF-----FAKNGYRLMDSSMYTQPIQT------------------------PTQYPSPVFMQPVYNP-QQYSVYS-LVPQSWSP-------------------------------------SPAPYFETPLAPFPNG--------------------------------------------------------------------------------------------------------------------------------SFVNGFSSPGSYKTNAAAMNMGRPFPKNRVKPHFR----------SSSGSEHSTEGSVSLGDGPLSRSSSRIFLSERHNPTVTGQQEQTYLPKEAPILQMEQNGD-----FGRGRRTLFRG--------------------------RRRRDDDR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IPRPQPAATEAKAPTPKFDLLATNFPPLPG------SSSRVPDELGLEN----------------------------------------------------------------------RMSDVVKG----------------------------------------------------VCREKDSEDVRVSCPVPAEDGQTDCTSAP-LSISPSPPCTAEPPVLS-TTQQEQDQMEDS------------------------------------------AVPKDTLNPVAVPVSSPTATKPS----------------PANTASPCTSNINPPRAVALQEPRKLSYAEVCQKPPKEPSPVLVQPLRELRSNAVSPTR-------NEENGAPEKPVE--KPHEKPETRASKDHSG-------------------------------FRGNTIPRGAAGKIREQRRQ--FSHRATPQ-GVTRRNGKEQYVPPRSPK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q71RC2-1", "uniprot_id": "LARP4_HUMAN", "id": "Q71RC2-1", "name": "La-related protein 4", "aln": "---------------------------------------------------------MLLFVEQVASKGTGLNPNAKVW-QEIAPGNTDATPVTHG------TESSWHEIAATSGAHPEGNAELS------EDICKEYEVMYSSSCETTRNTTGIEESTDG---------------MILGPE--DLSYQIYD-VSGESN---------------------------------------------------------------SAVSTEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLILEVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCPKVISCEFAHNSNWYITFQSDTDAQQAFKYLREEVKTFQGKPIMARIKAINTF-----FAKNGYRLMDSSIYSHPIQT------------------------QAQYASPVFMQPVYNPHQQYSVYS-IVPQSWSP-------------------------------------NPTPYFETPLAPFPNG--------------------------------------------------------------------------------------------------------------------------------SFVNGFNSPGSYKTNAAAMNMGRPFQKNRVKPQFR----------SSGGSEHSTEGSVSLGDGQLNRYSSRNFPAERHNPTVTGHQEQTYLQKETSTLQVEQNGD-----YGRGRRTLFRG--------------------------RRRREDDR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ISRPHPSTAESKAPTPKFDLLASNFPPLPG------SSSRMPGELVLEN----------------------------------------------------------------------RMSDVVKG----------------------------------------------------VYKEKDNEELTISCPVPA-DEQTECTSAQQLNMSTSSPCAAELTALS-TTQQEKDLIEDS------------------------------------------SVQKDGLNQTTIPVSPPSTTKPS----------------RASTASPCNNNINAATAVALQEPRKLSYAEVCQKPPKEPSSVLVQPLRELRSNVVSPTK-------NEDNGAPENSVE--KPHEKPEARASKDYSG-------------------------------FRGNIIPRGAAGKIREQRRQ--FSHRAIPQ-GVTRRNGKEQYVPPRSPK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PRY7-1", "uniprot_id": "A0A8M9PRY7_DANRE", "id": "A0A8M9PRY7-1", "name": "", "aln": "---------------------------------------------------------MTSESSGQAQQKAEVEPGSVVRDQEEKTGEKHGGMVTTKGAGLNPNAKVWQEVSAPTSQAPEAATETCHWPQADHVSTEEMEEGFKEYSVGYGDSESVPAMETG---------------LINGIESVELAYPLYEPVEGETLE------------------------------------------------------------EPPALSEESLKESLKKQLEFCFSRENLSKDLYLISQMDSDQFVPIWTIASMEDVKLLTTDMDLILEVLRASPMVQVDEKGEKVRPNHKRCIIILREVPETTPVEEVEALFKSEKCPQVISVEFAHNNNWYITFQSDTDAQQAYRYLREEVKTFQGKPIMARIKAINTF-----FAKNGFG-ADSGVYSS----------------------------PSQYSSPVYLQQVYQPPQQYPLYS-LLPQTWTP-------------------------------------SPTPYFETPLAPFPNS--------------------------------------------------------------------------------------------------------------------------------TFVNGFGTAGNYKTGTSPISLTRNYPRNRLPLYSR----------KNVINAFRNHVKPRADVGQLTETSSGAGSPQPPCTPSSDSNASTLTPLSEPPTSPRENQHSDLSISSRVRRGSYRG--------------------------MRRRREDE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RTRPN-AELEVKAPSPKFDLATTNFPPLPGGVSGHLPSVTVQTESVLEN----------------------------------------------------------------------RMADVVKG----------------------------------------------------ISKVPEASKQEVSQDTGTCQGEAQTTGPSVPALKP-PTTKVDPPVASVIHQVKKPVLEVQNAV---------------------------------------TLPDAAAAVTVNHVQLISAPKPT----------------CSQSTPSTASTPPLPTSTIVQEPRKLSYAEVCQRPPKDPPPVPVAPPSPTPSPSPTPNQPLRELRANKVDGPASSRCSPWDKLEKGESRTSREQTG-------------------------------YQRGNGSRGSGFKLREQQRRPPQGRRCSPQLGYNRRSGKEQNIPPRSPK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9I7T7-1", "uniprot_id": "LAR4_DROME", "id": "Q9I7T7-1", "name": "La-related protein Larp4B", "aln": "MEYFLGGYVYMNGDALKIQPPVYTNVPVETAMLATNLFGATTQIAASPAAAAAAHIPLITAAAAAAAAAGAPAVAPPVAVAPVATASAAQAAVVPAQQQQQAHPHQAQILAHTHVAHQQQQQQQQQTIQQHLHQQQQQQSPHPAQHLTYGHQPALSQATAGGSGTISGGAVGPSGVVVEGQD--TNEYAIMNGALGQTQDGTVVCYTTDALNNTNLVALDPQPHQIVVPVQVPVQVPVPVQLPANGSADPQQGSHNAAGGEEPNIPLDKLKQMLATQLEYYFSRENLANDTYLLSQMDSDQYVPIYTVARFNLVRKLTNDINLITEVLRESPNVQVDDKGLRVRPNRKRCIIILREISNNTPLDDVKALFSNESCPRPISCEFAANNSWYITFESDEDAQKAYKYLREEVKEFQGKPIMARIKPKSFINRIQAVPKNGYRLTSPPTANVFDPAGAGGATVSYAAAQQPRYLYTNGAAIAAPASVQYSNPVLIPIPQNQFYPGLVAGPWPPGTVAATTAHGQNFYELGGNIFTTNPLPPQPVTAGFAQAPPPTSQAMVTPKPQGGGRYNNNHRGNPNNVGGANSGPRAESRSKPPRSTPSASHIQGGNIMPIQITAPIPGGMVSVVPTNIVQDPLQPAPLQQQPQQVIQQIQQQPSSSAQQQQAATVQMNNTTRHYPIKSNWKGGMQKNLDKSYSGGVATHHHYTTQVQALPAHSHHLQAQQQLQGQTQQQHYQLASSSAASAPQVTYVTTAPAPQQPGQHQHHLVVQQTQPQQQQQQQQVVLQQQQVQVQELQEAGDGVEHSSHAMQQVNRSSNMSASSSSSLATSMSKEPLQWQNRPRRRRRDEEGGINYSPGGRVGLYGSSPSNPHPQQHLMSSSTGSNVQSAGGTDGGGASHRGGERQSHYNTIHDVPPPQHRGNYKGNNYNPHYHAQHSSMASGSHHHHHHNALSSQQQQHHLTTGTGQQGSGHHYHHHHHHNSIGSNVGNSGGLGVSSGGSGGGGSGGGSGSNSLSGGSNERGIHHSSLGYQGHQHQHQQQQQQQQQQQQQQPAAPVQPPQFDLEDAAFPPLPATSATAPHTPQATGGASLHNSTTSSSSSTGLGQKQTLHQQQQQAPQQHQVLSSSVESAGGDEQRSSNQQGIETSNIHLANSSTANNWVENRLSDVVRTGGGGGGGGKGKARKDNRHPQGQNQPHMAPNYQQHQPRNPPVSPTPALGAEYGIQIQEGNNTKNVTKQSSSNNNSIHVIKCQTPNINASSKEEAAGAQQQQQQQLDKSNKTEDEMHPKQPSQQRLVEGYVQQQQLPLLAAHNEYSAALAAGAGACSVVEGGLTTSLAECSLGQHKKPPSVAALHAKKDANLLEKGASKHKSVATSTSTENLSAAATASKLSYAQVAQHHKAAASSDSKETGSGGSTGTLSPTG---SHKMDLVFGDPAVVVAAVEKSGLATVSTEKRVAGGASPAALIGKPAGGLPATNTTQGSSAVVVSAKEKDNRPNASVRPLSKEKQQQHYGSATEHNTNANIGLGASGNRKSRANNS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . * ... *. : : . : : :: : . . : * :: * : * : : . *:: . :. :.**: * .***: ******::* **:*******::**:*:* :: :: **.: :** **** ** ****:** :***.:****:****:.:.**:::*:.**..*.**: ** *** *..*****:** ***:*::******* ***********. . : ..***: .. . : .* : : * * * .*. ::. .*.* *.* :: ::* *:. :: .*. : *.* . .: . : : : .. . . : . : .. . . :: .: : *. *** ::. : : . .*:*** : *****. : *.* *::***: : . :: : : . . :.. . . . . * .: . : . . **. :.. . .. . *****:*.*: ... . : :*. : * . . :.: :* . . ...: : ::::: . : . . * . .*: : ", "identical_positions": 153, "similar_positions": 210, "identity": "9.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100729-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AE95-1", "uniprot_id": "D4AE95_RAT", "id": "D4AE95-1", "name": "", "aln": "MEMSAQRLTSNRTSPQSPSNSDYTWEYEYYEIG-PVSFEGLKAHKYSIVIGFWVGLAVFVIFMFFVLTLLTKTGAPHQDNAESSEKRFRMNSFVSDFGKPLESD--KVFSRQGNEESRSLFHCYINEVEH------LDRVKVCHRTTAIDSDVHLQEAI-------RSSGRPEEELTRFMQFDIPNFVNTDQN-SFGEDDLLISEPPVLLENKPVSQTSRTDLD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z1Q2-1", "uniprot_id": "MRAP2_MOUSE", "id": "D3Z1Q2-1", "name": "Melanocortin-2 receptor accessory protein 2", "aln": "MEMSAQRLASNRTSPQSPSNSDYTWEYEYYEIG-PVSFEGLKAHKYSIVIGFWVGLAVFVIFMFFVLTLLTKTGAPHQDNAESSERRFRMNSFVSDFGKPLESD--KVFSRQGNEESRSLFHCYINEVEH------LDRVKVCHQTTAIDSDVHLQEAS-------RSSGRPEEELARFMKFDIPNFVNTEQS-SFGEDDLLISEAPVLLENKPVSQTSRIDLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96G30-1", "uniprot_id": "MRAP2_HUMAN", "id": "Q96G30-1", "name": "Melanocortin-2 receptor accessory protein 2", "aln": "--MSAQRLISNRTSQQSASNSDYTWEYEYYEIG-PVSFEGLKAHKYSIVIGFWVGLAVFVIFMFFVLTLLTKTGAPHQDNAESSEKRFRMNSFVSDFGRPLEPD--KVFSRQGNEESRSLFHCYINEVER------LDRAKACHQTTALDSDVQLQEAI-------RSSGQPEEELNRLMKFDIPNFVNTDQN-YFGEDDLLISEPPIVLETKPLSQTSHKDLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F8W4H9-1", "uniprot_id": "MRP2A_DANRE", "id": "F8W4H9-1", "name": "Melanocortin-2 receptor accessory protein 2A", "aln": "--MPRFQLSNSTSVP----NHNYEWSYEYYDDEEPVSFEGLKAHRYSIVIGFWVGLAVFVIFMFFVLTLLTKTGAPHPEAAEPYEKRMRLTSCADGLGRQRETDGRTGLSRPLLEESRSLFHCYINEEEREGGRAATDAGALTHGRSGIGNSRGQVEEVGLVVQNMVLESRAEREAALLAHFNIPNFVNSELNSALGDEDLLLGDPPIIMEEARP-RCTHHIID", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. :* .. : * :* *.****: **********:******************************** : **. *:*:*:.* ...:*: *.* . :** ************* *: * * :.:... * ..:.*.* : :*:******:: . :*::***:.:.*:::* : :: :*", "identical_positions": 95, "similar_positions": 55, "identity": "42.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100729-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UH60-1", "uniprot_id": "DIP2B_MOUSE", "id": "Q3UH60-1", "name": "Disco-interacting protein 2 homolog B", "aln": "MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYS--PQTQETDSIG------------------------------------------------------QKE-RNQTPAPTAAQTSAP---------------------------------SKYHRSR----SGGARDERYRSDIHTEAVQAALAKHKEQ-KMALPMPTKRRSTFVQSP----ADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQGSSTSSSASSTLSHGEVKGTSG-------------------------SLADVFANTRIEN-VSAPPDVTATTSSSSSS--LRPANIDLPPSGIVKGMHKGSNRSS-LMDTAD------GVPVNSRVSTKIQQLLNTLKRPKRPPLKEFFVDDSEEIVEGIPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGSTQAKCPCLTGLDVTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTK--NEPVLKPGDRVALVYPNNDPVMFMVAFYGCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEICLKGLPK-TQNGEIVQFKG----WPRLKWVVTDSKYLSKPPKDWQP-HISPAGTEPAYIEYKTSKEGSVMGVTVSRLAMLSQCQALSQACN-----YSEGETVVNVLDFKKDAGLWHGMFANVMNKMHTISVPYSVMKTCPLSWVQRVHAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSVSSCDAFLSLFQSHGLKPEAICPCATSAEAMTVAIRRPGVPGAPLP----GRAILSMNGLSYGVIRVNTEDKNSALTVQDVGHVMPGGMMCIVKPDGLPQLCRTDEIGEICVSSRTGGMMYFGLAGVTKNTFEVIP--------------VTSSGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADDIVATGLAVESIKTVYRG---------------------------------------------RIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLG-GIHISQTKQLFLEGSLHPCNILMCPHTCVTN-LPKPRQKQP-------------------GVGPASVMVGNLVAGKRIAQAAGRDLGQIEENDLVRK--------HQFLAEILQWRAQATPDHVLFMLLNAKGTTVCTASCLQLHKR-----------AERIASVLGDKGHLNAGDNVVLLYPPGIELIAAFYGCLYAGCIPVTVRPPHAQNLTATLPTVRMVVDVSKAACVLTTQTLMRLLKSREAAAAVDVKTWPAIIDTDDLPRKRLPQLYKPPTPEMLAYLDFSVSTTGMLTG------------------VKMSHSAVNALCRAIKLQCELYSSRQIAICLDPYCGLGFALWCLCSVYSGHQSVLIPPMELENNLFLWLATVNQYKIRDTFCSYSVMELCTKGLGNQVEVLKTRGINLS----------------CIRTCVVVAEERPRVSLQQSFSKLFKDIGLSPRAVSTTFGSRVNVAICLQGTSGPDPTTVYVDLKSLRHDRVRLVERG---APQSLLLSESGKILPGVKVVIVNPETKGPVGDSHLGEIWVNSPHTASGYYTIYDSET------LQADHFNTRLSFGDAAQTLWARTGYLGFVRRTELTAAT----------------------------------------------------GERHDALYVVGALDETLELRGLRYHPIDIETSVSRVHRSIAECAVFTWTNLLVVVVELCGSEQEALD-LVPLVTNVVLEEHYLIVGVVVVVDP-GVVPINS----------RGEKQRMHLRDSFLADQLDPIYVAYNM-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M0J6-1", "uniprot_id": "A0ABK0M0J6_RAT", "id": "A0ABK0M0J6-1", "name": "", "aln": "MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYS--PQTQETDSTG------------------------------------------------------QKE-RNQTPAPTAAQTSAP---------------------------------SKYHRSR----SGGARDERYRSDIHTEAVQAALAKHKEQ-KMALPMPTKRRSTFVQSP----ADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQGSSTSSSASSTLSHGEVKGTSG-------------------------SLADVFANTRIEN-VSAPPDVTATTSSSSSL--LRPANIDLPPSGIVKGMHKGSNRSS-LMDTAD------GVPVNSRVSTKIQQLLNTLKRPKRPPLKEFFVDDSEEIVE-VPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGTTQAKCPCLTGLDVTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTK--NEPVLKPGDRVALVYPNNDPVMFMVAFYGCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEICLKGLPK-TQNGEIVQFKG----WPRLKWVVTDSKYLSKPPKDWQP-HISPAGTEPAYIEYKTSKEGSVMGVTVSRLAMLSHCQALSQACS-----YSEGETVVNVLDFKKDAGLWHGMFANVMNKMHTISVPYSVMKTCPLSWVQRVHAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSVSSCDAFLSLFQSHGLKPEAICPCATSAEAMTIAIRRPGVPGAPLP----GRAILSMNGLSYGVIRVNTEDKNSALTVQDVGHVMPGGMMCIVKPDGLPQLCKTDEIGEICVSSRTGGMMYFGLAGVTKNTFEVIP--------------VTSSGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADDIVATGLAVESIKTVYRGRHTGLLAVPQTCQARPHLRTFPLSAPSARNPLPPDLRVARVLTSFRIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDTIHQVGVYCLALVPANTLPKTPLG-GIHISQTKQLFLEGSLHPCNILMCPHTCVTN-LPKPRQKQP-------------------GVGPASVMVGNLVAGKRIAQAAGRDLGQIEENDLVRK--------HQFLAEILQWRAQATPDHVLYVLLNAKGTTVCTASCLQLHKR-----------AERIASVLGDKGHLNAGDNVVLLYPPGIELIAAFYGCLYAGCIPVTVRPPHAQNLTATLPTVRMVVDVSKAACVLTTQTLMRLLKSREAAAAVDVKTWPAIIDTDDLPRKRLPQLYKPPTPEMLAYLDFSVSTTGMLTG------------------VKMSHSAVNALCRAIKLQCELYSSRQIAICLDPYCGLGFALWCLCSVYSGHQSVLIPPMELESNLSLWLATVNQYKIRDTFCSYSVMELCTKGLGSQVEALKTRGINLS----------------CIRTCVVVAEERPRVTLQQSFSKLFKDIGLSPRAVSTTFGSRVNVAICLQGTSGPDPTTVYVDLKSLRHDRVRLVERG---APQSLLLSESGKILPGVKVVIVNPETKGPVGDSHLGEIWVNSPHTASGYYTIYDSET------LQADHFNTRLSFGDAAQTLWARTGYLGFVRRTELTAAT----------------------------------------------------GERHDALYVVGALDETLELRGLRYHPIDIETSVSRVHRSIAECAVFTWTNLLVVVVELCGSEQEALD-LVPLVTNVVLEEHYLIVGVVVVVDP-GVVPINS----------RGEKQRMHLRDSFLADQLDPIYVAYNM-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P265-1", "uniprot_id": "DIP2B_HUMAN", "id": "Q9P265-1", "name": "Disco-interacting protein 2 homolog B", "aln": "MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYS--PQTQETDSAV------------------------------------------------------QKELRNQTPAPSAAQTSAP---------------------------------SKYHRTR----SGGARDERYRSDIHTEAVQAALAKHKEQ-KMALPMPTKRRSTFVQSP----ADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQGSSTSSSASSTLSHGEVKGTSG-------------------------SLADVFANTRIEN-FSAPPDVTTTTSSSSSSSSIRPANIDLPPSGIVKGMHKGSNRSS-LMDTAD------GVPVSSRVSTKIQQLLNTLKRPKRPPLKEFFVDDSEEIVE-VPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGTTQAKCSCLTALDMTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTK--NEPVLKPGDRVALVYPNNDPVMFMVAFYGCLLAEVIPVPIEVPLTRKDAGGQQIGFLLGSCGIALALTSEVCLKGLPK-TQNGEIVQFKG----WPRLKWVVTDSKYLSKPPKDWQP-HISPAGTEPAYIEYKTSKEGSVMGVTVSRLAMLSHCQALSQACN-----YSEGETIVNVLDFKKDAGLWHGMFANVMNKMHTISVPYSVMKTCPLSWVQRVHAHKAKVALVKCRDLHWAMMAHRDQRDVSLSSLRMLIVTDGANPWSVSSCDAFLSLFQSHGLKPEAICPCATSAEAMTVAIRRPGVPGAPLP----GRAILSMNGLSYGVIRVNTEDKNSALTVQDVGHVMPGGMMCIVKPDGPPQLCKTDEIGEICVSSRTGGMMYFGLAGVTKNTFEVIP--------------VNSAGSPVGDVPFIRSGLLGFVGPGSLVFVVGKMDGLLMVSGRRHNADDIVATGLAVESIKTVYRG---------------------------------------------RIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVPANTLPKTPLG-GIHISQTKQLFLEGSLHPCNILMCPHTCVTN-LPKPRQKQP-------------------GVGPASVMVGNLVAGKRIAQAAGRDLGQIEENDLVRK--------HQFLAEILQWRAQATPDHVLFMLLNAKGTTVCTASCLQLHKR-----------AERIASVLGDKGHLNAGDNVVLLYPPGIELIAAFYGCLYAGCIPVTVRPPHAQNLTATLPTVRMIVDVSKAACILTSQTLMRLLRSREAAAAVDVKTWPTIIDTDDLPRKRLPQLYKPPTPEMLAYLDFSVSTTGMLTG------------------VKMSHSAVNALCRAIKLQCELYSSRQIAICLDPYCGLGFALWCLCSVYSGHQSVLIPPMELENNLFLWLSTVNQYKIRDTFCSYSVMELCTKGLGNQVEVLKTRGINLS----------------CVRTCVVVAEERPRVALQQSFSKLFKDIGLSPRAVSTTFGSRVNVAICLQGTSGPDPTTVYVDLKSLRHDRVRLVERG---APQSLLLSESGKILPGVKVVIVNPETKGPVGDSHLGEIWVNSPHTASGYYTIYDSET------LQADHFNTRLSFGDAAQTLWARTGYLGFVRRTELTAAT----------------------------------------------------GERHDALYVVGALDETLELRGLRYHPIDIETSVSRIHRSIAECAVFTWTNLLVVVVELCGSEQEALD-LVPLVTNVVLEEHYLIVGVVVVVDP-GVIPINS----------RGEKQRMHLRDSFLADQLDPIYVAYNM-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BAI5-1", "uniprot_id": "A0A8M3BAI5_DANRE", "id": "A0A8M3BAI5-1", "name": "", "aln": "MAERGVD-----VSALPQEVREQLAELDLELSEGDITQKGYEKKRAKVLAPYL--AQAQDLAPPP------------------------------------------------------AYD--EQSPGPSSASAPEPGPS------------------------NSSSSSSRHRRTRRPHRSGGTRDERYRSDIHTEAVQAALAKHKEE-KMALPMPTKRRSTYVQSP----IDNCTPPDSSSSSDDE-------AVSSESAGPQQSSDTWINSSLHGSSTSSSASSTLSHGESRPTQNPQPQSQQLPPPPAPAHPPHSHSQPSALAEAFAQTRIVRRIGRDPVGGVGPPEVPSQAQARGSRVDLPANAVVRGMSRGQSRSS-MMETADVRRVGRGVPVSSRVSTKIQQLLNTLKRPKRPPLSEFFMDDQEEIVE-VPRADPNTPRPEGRQIIPVKGEPLGVVSNWPPALQAALARWGATQGKSPALTALDITGKPLYTLTFGKLWSRSVKLAYTLLNKLGTK--NEQILKPGDRVALVYPNSDPGMFWVAFYGCLLAEVIPVPIEVPLSRKDAGSSQVGFLLGSCGVGLALTSEICLKGLPK-TPTGEILQFKG----WPRLKWVVTDSKYLTKPSKDWQP-HIPTANTDTAYIEYKASKEGTVMGVAVSKVAMLTHCQALSQACN-----YCEGETLVNVLDFKKDMGLWHGVLTSVMNRIHTISVPYAVMKACPLSWVQRVHIHKARVALVKCRDLHWAMMAHRDQRDTSLASLRMLIVADGANPWSVSSCDAFLNVFQAHGLKPEVICPCATSPEAMTVAIRRPGISGAPLP----ARAVLSMTGLSHGVIRVNTEDKNSALTVQDVGHVMPGALMCIVKPDGPPMLCKTDEIGEIVVNSRAGGNMYYGLSGVTKNTFEVIP--------------VNASGAPIGEIPFVRSGLLGFVGPGSLIFVVGKNEGLLMVSGRRHNADDLVATALAVEPVKTVYRG---------------------------------------------RIAVFSVTVFFDERIVIVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGLYCLALVPANTLPKTPLG-GIHISDTKQLFLEGALHPCNILMCPHTCVTN-MPKPRQKQPV------------------GVGPASIMVGNLVAGKRIAQAAGRDLGLIEDQDLVRKLCMWPTMMHQFLTEALQWRAQTDPDHTLYVLLNAKGVAVCTATCVQLHKR-----------AEKIAAALMERSGINIGENVVLLYPPGIDLIAAFYGCLYAGCIPVTVRPPHPQNLSATLPTVRMIIDVSKAACILTTQVLTKILRSKEAAATVNIKTWPIIIDTDDLPRKRPPTIYKPPNAEMIAYLDFSVSTTGMLTG------------------VKISHAAVSALCRSIKLQCELYSSRQIAICLDPYCGLGFVLWCLASVYSGHQSILIPPMELETSLTLWLGTLSQYRIRDTFCSYSVMELCTKGLGGQTELLKARGVNLS----------------CVRSCVVIAEERPRLALTHSFSKLFKDIGLSMRAVSTAFGSRVNLAICLQGTTGPDPSTVYVDMKSLRHDRVRLVERG---APQSLPLMESGTILPGVRVVIVNPETRGPLGDSHLGEIWVNSPHNATGYYTIYGEEN------LQADHFNTKLSFGDP-QTLWARTGYLGFVKRTELTDAS----------------------------------------------------GDRHDALFVVGYLDETLELRGLRYHPIDIETSVSRAHRSIGESAVFTWTNLLVVVAELCGSEQDALD-LVPLVTNVVLEEHHLIVGVVVIVDP-GVIPINS----------RGEKQRMHLRDSFLADQLDPIYVAYNM-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0S9-1", "uniprot_id": "DIP2_DROME", "id": "Q9W0S9-1", "name": "Disco-interacting protein 2", "aln": "MEH---------TASLPGYVREKLAELDLELSEGDITQKGYEKKRAKLLQPFLKKPEGDKVKSTPPPPYYNVKNANNSTNHGNINNDGVIVSSEGYSYVTEVPSLSSSQQRHSKKIDFHQQAAMSLSSAPQSGNAGAPGYENMRPQGGAVGDPGYQNTREPSAFQNQQSTNNSQHRQRRTQRKVTHNEKRYHSEVRQEAVQQALAALKGRPKPSLPMPSKRTSVLNRSPGCNDELDSSTDDESIPEETISPDKEYNYPRDHISNSILPPEPIIKPPIRESSMGSQQHARTDVKQNQITNQKYTAPN-------------SAPERRPPQNLPPLPTSEPLSSDYPPIAYKRENDFSDKAFKQKQYNAPDITQFNNAHRAADRVTRYVNVSQNELNETDANGKWKVSAKIQQLLNTLKRPKRRPLPEFYEDNDIELEIAANTKDPNAPKPEGSTMTPVQGEQLSIPAGLPRTLECALQRYGTNSFKSPMATVLDPNGKVTTTLTYGKLLSRAQKIAHALSTKIFSKGPEQVTLKPGDRVALVYPNNDPLSFITAWYGCMFRGLVPLPIELPLSSSDTPPQQVGFLLSSCGITVALTSEACLKGLPKSTTTGEIAKLKG----WPRLQWFVT--EHLPKPPKEFNVGNLRADDSAAAYIEYTTDKEGSVMGVTVTRAAMINHCRALTMACH-----YTEGETIVCVLDFKREVGLWHSVLTSVLNGMHVIFIPYALMKLRPSSWMQLITKHRASCCLVKSRDLHWGLLATKDHKDISLSSLRMLLVADGANPWSLSSCDQFLSVFQAKGLRSDAICPCASSSEVFTVSLRRPGRGSCGFSPSATGRGVLSMAALSHGVVRVDSEDSLTSLTLQDCGQVMPAAQMVVVRSEGPPVLCKTDQVGEICVTSGSTSASYFGLDGMTNSTFKVQPLLEELEQPKDGNGTVNIISKPIGEDFYVRSGLLGFLGPGGLVFVCGSRDGLMTVTGRKHNADDIIATVLAVEPMRFIYRG---------------------------------------------RIAVFSIKVLRDERVCVIAEQRPDCSEEESFQWMSRVLQAVDSIHQVGIYCLALVPPNHLPKTPLG-GIHLCEARRRFLEGSLHPANVLMCPHTCVTN-LPKPRELHQGVQTAAKLSSSSGCGITDTGVGPASVMVGNLVQGNRLAEAHGRDVGLAEDCE--RK--------PQLITGVLRWRANTSPDHIIFTLLNSKGAIAKTLTCSELHKR-----------AEKIAALLQERGRIEPGDHVALIFPPGLDLLCAFYGCLYLGAIPITIRPPHPQNLNTTLPTVRMIVDVSKSGIVLSIQPIIKLLKSREAATSIDPKTWPPILDIDDNPKRKYAGIAT-VSFDSSAYLDFSVSTCGRLSG------------------VNITHRSLSSLCASLKLACELYPSRHVALCLDPYCGLGFVMWTLIGVYSGHHSILIAPYEVEANPSLWLSTLSQHRVRDTFCSYGVIELCTKALSNSIPSLKQRNIDLR----------------CVRTCVVVAEERPRVQLTQQFCKLFQALGLNTRCVSTSFGCRVNPAICVQGASSAESAQVYVDMRALRNNRVALVERG---APNSLCVIESGKLLPGVKVIIANPETKGHCGDSHLGEIWVQAPHNANGYFTIYGDET------DYNDHFNAKLVTGAT-SELYARTGYLGFLRRTECSQSASLLDETTPSVASRDSDTESLNSISQLQLNFSNVSLGGNSEHSLVGGASNANDQELHDAVYVVGAVDEVISLRGMNYHPIDIENSVMRCHKKIAECAVFTWTNLLVVVVELDGNESEALD-LVPLVTNTVLEDHQLIVGVVVVVDP-GVVPINS----------RGEKQRMHLRDGFLADQLDPIYVAYNM-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12275-1", "uniprot_id": "CRM2_YEAST", "id": "Q12275-1", "name": "Homeostatic regulator of DAG", "aln": "-------MDFSIPPTLPLDLQSRLNELIQDYKDENLTRKGYETKRKQLLDKFE------------------------------------------------------------------------ISQMRPYTPLRSP--------------------------------------------NSRKSKHLHRRNTSLASSITSLPNSIDRRHSIYRVTTINSTSANNTP----RRRSKRYTASLQSSLPGSSDENGSVKDAVYNPMIP----LLPRHTGAENTSSGDSAMTDSLPLILRG-------------------------RFEHYDGQTAMISINSKGKETFITWDKLYLKAERVAHELNKSHLYKMDKILLWYNKNDVIEFTIA--------LLGCFISGMAAVPVSFETYSLREILEIIKVTNSKFVLISNACHRQLDNLYSSSNHSKVKLVKNDVFQQIKFVKTDDLGTYTKAKKTSPTFDIPNISYIEFTRTPLGRLSG--VVMKHNILINQFET-----MTKILNSRSMPHWKQKSQSIRKPFHKKIMATNSRFVILNSLDPTRSTGLIMGVLFNLFTGNLMISIDSSILQRPG-GYENIIDKFRADILLNDQLQLKQVVINYLENPESAFSKKHKIDFSCIKSCLTSCTTIDTDVSEMVVHKWLKNLGCIDAPFCYSPMLTLLDFGGIFISIRDQLGNLENFP-IHNSKLRLQNELFINREKLKLNEVECSITAMINSSSSFKDYLKLETFGFPIPDITLCVVNPDTNTLVQDLTVGEIWISSNHITDEFYQMDKVNEFVFKAKLNYSEMFSWAKYEMPTNEKSQAVTEQLDTILNICPANTYFMRT----KLMGFVHNGKIYVLSLIEDMFLQNRLIRLPNWAHTSNLLYAKKGNQSAQPKGNTGAESTKAIDIS--------------SLSGETSSGYKRVVESHYLQQIT-ETVVRTVNTVFEVAAFELQHHKEEHFLVMVVESSLAKTEEES--------------------------------------------------KNGETTDTTLMKFAETQRNKLETKMNDLTDQIFRILWIFHKIQPMCILVVPRDTLPRRYCSLELANSTVEKKFLNNDLSAQFVKFQFDNVILDFLPHSAYYNESILSEHLSKLRKMALQEEYAMIEPAYRNGGPVKPKLALQCSGVDYRDESVDTRSHT----KLTDFKSILEILEWRISNYGNETAFSDGTNTNLVNSSASNDNNVHKKVSWASFGKIVAGFLKKIVGSKIPLKHGDPIIIMCENSVEYVAMIMACLYCNLLVIPLPSVKESVIEEDLKGLVNIIQSYKVKRVFVDAKLHSLLNDNNVVNKCFKKYKSLIPKITVFSKVKTKNALTVSMFKNVLKQKFGAKPGTRIGMTPCVVWVNTEYDVTSNIHVTMTHSSLLNASKIVKETLQLRNNSPLFSICSHTSGLGFMFSCLLGIYTGASTCLFSLTDVLTDPKEFLIGLQNLNVKDLYLKLETLYALLDRASSLIEGFKNKKENINSAKNNTSGSLREDVFKGVRNIMIPFPNRPRIYTIENILKRYSTISLSCTQISYVYQHHFNPLISLRSYLDIPPVDLYLDPFSLREGIIREVNPNDVSAGNYIKIQDSGVVPVCTDVSVVNPETLLPCVDGEFGEIWCCSEANAFDYFVCNSSKNKLYKDPFITEQFKSKMKSEVNNTLSYLRTGDLGFIKNVSCTNSQG--------------------------------------------------EVVNLNLLFVLGSIHESIEILGLTHFVSDLERTVKDVHSDIGSCLIAKAGGLLVCLIRCKERHNPILGNLTTLIVSELLNKHGVILDLCTFVRTKGISPKNSSMIMEVWAKNRASIMQAWFDQKIQIEAQFGINYGENISIYLLSDYEKDNI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:** :: :* ** : .: ::*:****.** ::* : : * . .. :: : : :*. . : :.: . : .:* .. * .. . : :. *. : . . . . . : . . .: . :* :. . . * * : :. : .. *: .: . * : . ... : . . *:* . : : : : . * : :: : :... : .:: :: . * .* . : :*.*:. : :: : .: * . * :::. :*: . ::* :* . :. : . : : : : * :.* : * . . * .: : * : : : . :. : : : :* . : : : :.: .. . *: .. :** . ..:* . :. .: . . .* :: : . . :*.: . .:*. . .:. :. *:. .:: :. . : ... . * * ... . . * :.* * : :: . .. : . ::*: :.::. : . : .. . * : .** : : * . : .:::: : :*:: *: :** : **: . : . ..: **:. * . : : .. : : :*:. : .: .: *. * : :. * * . :. : : *.** . :. : . .. : : : :: * : : .: :: *: : :: .:: :. : .*** . : :.: . : . : * : ::: * :: : :*...:.. * . * . .: : . . .*.... : *.::* :: . :* :* . : . .**** : * .:*:* : *:. :: . :* :.: .::* : . .: . .. :* : :: :*. :: :***: ..: * :. :.*. :* : :.* *.::. . . :*:* :**.. : *: . * : : : :** : . * :.**** *..:**** : .* .*:. ..:. ::*:::: : *** ***::... : : : ::*:* :.* :.: *: :. *:* :* * .*... : . .*** : . .. *. *..*:.. :*:.* :*:.: ..* . *: * ** *.. : : : : : * . *: ", "identical_positions": 164, "similar_positions": 511, "identity": "8.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100729-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AE95-1", "uniprot_id": "D4AE95_RAT", "id": "D4AE95-1", "name": "", "aln": "MEMSAQRLTSNRTSPQSPSNSDYTWEYEYYEIG-PVSFEGLKAHKYSIVIGFWVGLAVFVIFMFFVLTLLTKTGAPHQDNAESSEKRFRMNSFVSDFGKPLESDKVFSRQGN-EESRSLFHCYINEVEHLDRVKVCHRTTAIDSDVHLQEAIRSSGRPEEELTRFMQFDIPNFVNTDQNS-FGEDDLLISEPPVLLENKP----VSQTSRTDLD----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z1Q2-1", "uniprot_id": "MRAP2_MOUSE", "id": "D3Z1Q2-1", "name": "Melanocortin-2 receptor accessory protein 2", "aln": "MEMSAQRLASNRTSPQSPSNSDYTWEYEYYEIG-PVSFEGLKAHKYSIVIGFWVGLAVFVIFMFFVLTLLTKTGAPHQDNAESSERRFRMNSFVSDFGKPLESDKVFSRQGN-EESRSLFHCYINEVEHLDRVKVCHQTTAIDSDVHLQEASRSSGRPEEELARFMKFDIPNFVNTEQSS-FGEDDLLISEAPVLLENKP----VSQTSRIDLD----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96G30-1", "uniprot_id": "MRAP2_HUMAN", "id": "Q96G30-1", "name": "Melanocortin-2 receptor accessory protein 2", "aln": "--MSAQRLISNRTSQQSASNSDYTWEYEYYEIG-PVSFEGLKAHKYSIVIGFWVGLAVFVIFMFFVLTLLTKTGAPHQDNAESSEKRFRMNSFVSDFGRPLEPDKVFSRQGN-EESRSLFHCYINEVERLDRAKACHQTTALDSDVQLQEAIRSSGQPEEELNRLMKFDIPNFVNTDQNY-FGEDDLLISEPPIVLETKP----LSQTSHKDLD----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DM64-1", "uniprot_id": "MRP2B_DANRE", "id": "P0DM64-1", "name": "Melanocortin-2 receptor accessory protein 2B", "aln": "--MSEY---SNR----SQAGADYEWHYEYYEDEEPVSFEGLRANRYSIVIGFWVGLAVFVIFMFFVLTLLTKTGAPHPEMCDASMKPHVLIGCELEVGGSLA----FSLPPLPDQSRSLFHFYIHKEE---RVKT-HKDAVIGRGMHCGRG--NAERADEDEHFMSSFNIPNFVNSEQSSSLGHDDFLLSEPPIITDGQSDELKTAEPAHLCYDIIRH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** *** * :.:** *.***** *******:*::******************************** : .::* : . : . :.* .* ** ::****** **:: * *.*. *: :.:. .:: .. .: :.:*: : .*:******::*. :*.**:*:**.*:: : :. ::.:: * ", "identical_positions": 88, "similar_positions": 61, "identity": "40.37%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100802-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35526-1", "uniprot_id": "STX1A_MOUSE", "id": "O35526-1", "name": "Syntaxin-1A", "aln": "-MKDRTQELRTAK-DSDDDDD--VTVTVD---RDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGN-PAIFASGIIMDSS--ISKQALSEIETRHSEIIKLETSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARR-KKIMIIICCVILG-IIIASTIGGIFG---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32851-1", "uniprot_id": "STX1A_RAT", "id": "P32851-1", "name": "Syntaxin-1A", "aln": "-MKDRTQELRTAK-DSDDDDD--VTVTVD---RDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGN-PAIFASGIIMDSS--ISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARR-KKIMIIICCVILG-IIIASTIGGIFG---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16623-1", "uniprot_id": "STX1A_HUMAN", "id": "Q16623-1", "name": "Syntaxin-1A", "aln": "-MKDRTQELRTAK-DSDDDDD--VAVTVD---RDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGN-PAIFASGIIMDSS--ISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSDTKKAVKYQSKARR-KKIMIIICCVILG-IVIASTVGGIFA---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24547-1", "uniprot_id": "STX1A_DROME", "id": "Q24547-1", "name": "Syntaxin-1A", "aln": "MTKDRLAALHAAQSDDEEETE--VAVNVDG--HDSYMDDFFAQVEEIRGMIDKVQDNVEEVKKKHSAILSAPQTDEKTKQELEDLMADIKKNANRVRGKLKGIEQNIEQEEQQNKSSADLRIRKTQHSTLSRKFVEVMTEYNRTQTDYRERCKGRIQRQLEITGRPTNDDELEKMLEEGN-SSVFTQGIIMETQ--QAKQTLADIEARHQDIMKLETSIKELHDMFMDMAMLVESQGEMIDRIEYHVEHAMDYVQTATQDTKKALKYQSKARR-KKIMILICLTVLG-ILAASYVSSYFM---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1PT03-1", "uniprot_id": "A0A8M1PT03_DANRE", "id": "A0A8M1PT03-1", "name": "Syntaxin-1A", "aln": "-MKDRTQELRHGK-ELEEQNE--VTMNNKMVIEDGFMDEFFEQVEEIREFIDSLAEKVGEVKRNHSATLASPNPDEKTKTEFEELMNDIKTLANKVRSRLQHIQQSIEHEEAFNGQSADVRIRKTQHSTLSRKFVEVMSEYNAAQSEYRERCKGRIQRQLEITGRKTTKEELETILESDN-PSIFTTGVFMDCS--ITKQAMNEIETRHNEIIQLESCIRELQDMFVDLAVLVENQGELINNIETNVSSAQEYVEKAKEETKAAIKIQKTSRT-KLILIGGCVSVCVLILIIALIFGLT----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P39926-1", "uniprot_id": "SSO2_YEAST", "id": "P39926-1", "name": "Protein SSO2", "aln": "MSNANPYENNNPYAENYEMQEDLNNAPTGHSDGSDDFVAFMNKINSINANLSRYENIINQIDAQHKDLLTQVS--EEQEMELRRSLDDYISQATDLQYQLKADIKDAQRDGLHDSN------KQAQAENCRQKFLKLIQDYRIIDSNYKEESKEQAKRQYTIIQPEATDEEVEAAINDVNGQQIFSQALLNANRRGEAKTALAEVQARHQELLKLEKTMAELTQLFNDMEELVIEQQENVDVIDKNVEDAQQDVEQGVGHTNKAVKSARKARKNKIRCLIICFIIFAIVVVVVVVPSVVETRK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32867-1", "uniprot_id": "SSO1_YEAST", "id": "P32867-1", "name": "Protein SSO1", "aln": "MSYNNPYQLETPFEESYELDE--GSSAIG-AEG-HDFVGFMNKISQINRDLDKYDHTINQVDSLHKRLLTEVN--EEQASHLRHSLDNFVAQATDLQFKLKNEIKSAQRDGIHDTN------KQAQAENSRQRFLKLIQDYRIVDSNYKEENKEQAKRQYMIIQPEATEDEVEAAISDVGGQQIFSQALLNANRRGEAKTALAEVQARHQELLKLEKSMAELTQLFNDMEELVIEQQENVDVIDKNVEDAQLDVEQGVGHTDKAVKSARKARKNKIRCWLIVFAIIVVVVVVVVVPAVVKTR-", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : : : *: ::..*. :. . : ::. *. *: . *: .:. : : *. :: :*: :. ::: : . :::* .. ::*:::: :*. :::*:*. * : :** * :..:*:* :.. . :*: .:: :* :: ::::**.::::**. : ** ::* *: ** .* * :: *: :*. * *: . .*. *:* .:* * : :: : . ", "identical_positions": 41, "similar_positions": 109, "identity": "13.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100805-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C0L5-1", "uniprot_id": "CO4B_HUMAN", "id": "P0C0L5-1", "name": "Complement C4-B", "aln": "----MRLLWGLIWASSFFTLSLQKPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFTLSSERDFALLSLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTIT-VMVENSHGLRVRKKEVYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKT----FFRGLESQTKLVNGQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIESPGGEMEEAELTSWYFVSSPFSLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQDIQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIERPDSRPPRVGDTLNLNLRAVGS-GATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPSFYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGE-----SVKLHLETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAFSDGDQWTLSRKRLSCPKEK-TTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMRSCEQRAARVQQP---DCREPFLSCCQFAESLRKKSRDKGQAGLQR-ALEILQEEDLIDEDDIPVRSFFPENWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQVLVPAG--SARPVAFSVVPTAATAVSLKVVARGSFEFPVGDAVSKVLQIEKEGAIHREELVYELNPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFRKADGSYAAWLSRGSSTWLTAFVLKVLSLAQEQVGGS------------PEKLQETSNWLLSQQQADGSFQDLSPVIHRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKASSFLGEKASAGLLGAHAAAITAYALTLTKAPADLRGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQAAAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYYPRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCRLRLEPGKEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQGCQV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0C0L4-1", "uniprot_id": "CO4A_HUMAN", "id": "P0C0L4-1", "name": "Complement C4-A", "aln": "----MRLLWGLIWASSFFTLSLQKPRLLLFSPSVVHLGVPLSVGVQLQDVPRGQVVKGSVFLRNPSRNNVPCSPKVDFTLSSERDFALLSLQVPLKDAKSCGLHQLLRGPEVQLVAHSPWLKDSLSRTTNIQGINLLFSSRRGHLFLQTDQPIYNPGQRVRYRVFALDQKMRPSTDTIT-VMVENSHGLRVRKKEVYMPSSIFQDDFVIPDISEPGTWKISARFSDGLESNSSTQFEVKKYVLPNFEVKITPGKPYILTVPGHLDEMQLDIQARYIYGKPVQGVAYVRFGLLDEDGKKT----FFRGLESQTKLVNGQSHISLSKAEFQDALEKLNMGITDLQGLRLYVAAAIIESPGGEMEEAELTSWYFVSSPFSLDLSKTKRHLVPGAPFLLQALVREMSGSPASGIPVKVSATVSSPGSVPEVQDIQQNTDGSGQVSIPIIIPQTISELQLSVSAGSPHPAIARLTVAAPPSGGPGFLSIERPDSRPPRVGDTLNLNLRAVGS-GATFSHYYYMILSRGQIVFMNREPKRTLTSVSVFVDHHLAPSFYFVAFYYHGDHPVANSLRVDVQAGACEGKLELSVDGAKQYRNGE-----SVKLHLETDSLALVALGALDTALYAAGSKSHKPLNMGKVFEAMNSYDLGCGPGGGDSALQVFQAAGLAFSDGDQWTLSRKRLSCPKEK-TTRKKRNVNFQKAINEKLGQYASPTAKRCCQDGVTRLPMMRSCEQRAARVQQP---DCREPFLSCCQFAESLRKKSRDKGQAGLQR-ALEILQEEDLIDEDDIPVRSFFPENWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVEGLCLAGGGGLAQQVLVPAG--SARPVAFSVVPTAAAAVSLKVVARGSFEFPVGDAVSKVLQIEKEGAIHREELVYELNPLDHRGRTLEIPGNSDPNMIPDGDFNSYVRVTASDPLDTLGSEGALSPGGVASLLRLPRGCGEQTMIYLAPTLAASRYLDKTEQWSTLPPETKDHAVDLIQKGYMRIQQFRKADGSYAAWLSRDSSTWLTAFVLKVLSLAQEQVGGS------------PEKLQETSNWLLSQQQADGSFQDPCPVLDRSMQGGLVGNDETVALTAFVTIALHHGLAVFQDEGAEPLKQRVEASISKANSFLGEKASAGLLGAHAAAITAYALTLTKAPVDLLGVAHNNLMAMAQETGDNLYWGSVTGSQSNAVSPTPAPRNPSDPMPQAPALWIETTAYALLHLLLHEGKAEMADQASAWLTRQGSFQGGFRSTQDTVIALDALSAYWIASHTTEERGLNVTLSSTGRNGFKSHALQLNNRQIRGLEEELQFSLGSKINVKVGGNSKGTLKVLRTYNVLDMKNTTCQDLQIEVTVKGHVEYTMEANEDYEDYEYDELPAKDDPDAPLQPVTPLQLFEGRRNRRRREAPKVVEEQESRVHYTVCIWRNGKVGLSGMAIADVTLLSGFHALRADLEKLTSLSDRYVSHFETEGPHVLLYFDSVPTSRECVGFEAVQEVPVGLVQPASATLYDYYNPERRCSVFYGAPSKSRLLATLCSAEVCQCAEGKCPRQRRALERGLQDEDGYRMKFACYYPRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDVKAAANQMRNFLVRASCRLRLEPGKEYLIMGLDGATYDLEGHPQYLLDSNSWIEEMPSERLCRSTRQRAACAQLNDFLQEYGTQGCQV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P08649-1", "uniprot_id": "CO4_RAT", "id": "P08649-1", "name": "Complement C4", "aln": "----MRLLWGLAWAFSFFASSLQKPRLLLFSPSVVNLGTPLSVGVQLLDAPAGQEVKGSVYLRNPTSG--PCSPKKDFKLSSGNDFVLLRLEVPLKDVRSCGLFGLRRAPHIQLVAHSPWLKNTASKATETQGVNLLFSSRRGHIFVQTDQPIYNPGQRVRYRVFALDQKMRPSTDTLT-VTVENSHGLRVRKKEVFAPTSIFQDDFIIPDISEPGTWKISARFSDGLESNRSTHFEVKKYVLPNFEVKLTPWKPYILTVPSYREEIQLDVQARYVYGKPVQGVAYTRFALMDEQGKKS----FLRGLETQTKLVEGQTHISISRDQFQAALGKVNTEIGDLEGLRLYAAVAVIESPGGEMEEAELTSWPFVSSAFSLDLSHTKQHLVPGAPFLLQALVREMSGSEASDVPVKVSATLLS-GSDSKVLDFQQNTNGIGQVSFSIHVPPTITELRLLVSAGSLYPAVAKLTVQAPPSRGPGFLSIEPLDLRSPRVGDTFVLSLRTVGIPMPTFSHYYYMIISRGQIMAMSREPRRALTSISVLVDHHLAPSFYFVAYFYHQGLPVANSLLINVQPGDCEGKLELKVDGAKEYRNGD-----SMKLQLQTDSEALVALGAVDTALYAVGGRSHKPLDMSKVFEVMNSYNLGCGPGGGDDALQVFQTAGLAFSDGDRLTQTKENLSCPKEK-KSRQKRNVNFQKAISEKLGQYSSPDTKRCCQDGMTKLPMARTCEQRAARVPQP---ACREPFLSCCKFAEDLRR-NQTRSQAGLAR-AQDMLQEEDLIDEDDILVRSFFPENWLWRVEPVDRSKLLTVWLPDSLTTWEIHGVSLSKSKGLCVAKPTRVRVFREFHLHLRLPISVRRFEQLELRPVLYNYLSEDVTVSVHVSPVEGLCLAGGGLLAQQVSVPAG--SARPVAFSVVPTAAASIPLKVVARG--SFTIGDAVSKILQIEKEGAIHREEIVYNLDPLNNLGRSLEIPGSSDPNVIPDGDFSSFVRVTASEPLETLGSEGALSPGGVASLLRLPRGCAEQTMIYLAPTLTASHYLDRTEQWSKLPPETKDHAVDLIQKGHMRIQQFRKKDGSFGAWLHRDSSTWLTAFVLKILSLAQEQIGDS------------PEKLQETAGWLLGQQLDDGSFHDPCPVIHRGMQGGLVGTDETVALTAFVVIALHHGLAVFQDENSQQLKKRVEASITKANSFLGQKASAGLLGAHASAITAYALTLTKASEDLQNVAHNSLMAMAEETGENLYWGSAIGSQDNVVSSTPAPRNPSEPVPQAPALWIETTAYGLLHLLLREGKGEMADKVATWLTHQGSFQGGFRSTQDTVVTLDALSAYWIASHTTEEKALNVTLSSMGRNGYKSHLLQLNNHQVKGLEEELKFSLGSTINVKVGGNSKGTLKILRTYNVLDMKNTTCQDLRIEVTVTGYVEYTREANEDYEY--DYDMPAADDPSVHSQPVTPLQLFEGRRSRRRREAPKAADEQESRVQYTVCIWRNGNLGLSGMAIADITLLSGFQALRADLEKLTSLSDRYVSHFETDGPHVLLYFDSVPTTRECVGFGALQEVAVGLVQPASAVLYDYYSPDHKCSVFYAAPTKSKLLSTLCSADVCQCAEGKCPRQRRSLERGVEDKDGYRMKFACYYPRVEYGFQVKVLREDSRAAFRLFETKITQVLHFTKDAKASIGQTRNFLVRASCRLRLEPSKEYLIMGMDGVTSDLKGDPQYLLDSNTWIEEMPSERLCRSTRQRAACGQLNDFLQEYSSQGCQV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P01029-1", "uniprot_id": "CO4B_MOUSE", "id": "P01029-1", "name": "Complement C4-B", "aln": "----MRLLWGLAWVFSFCASSLQKPRLLLFSPSVVNLGTPLSVGVQLLDAPPGQEVKGSVFLRNPKGG--SCSPKKDFKLSSGDDFVLLSLEVPLEDVRSCGLFDLRRAPHIQLVAQSPWLRNTAFKATETQGVNLLFSSRRGHIFVQTDQPIYNPGQRVRYRVFALDQKMRPSTDFLT-ITVENSHGLRVLKKEIFTSTSIFQDAFTIPDISEPGTWKISARFSDGLESNRSTHFEVKKYVLPNFEVKITPWKPYILMVPSNSDEIQLDIQARYIYGKPVQGVAYTRFALMDEQGKRT----FLRGLETQAKLVEGRTHISISKDQFQAALDKINIGVRDLEGLRLYAATAVIESPGGEMEEAELTSWRFVSSAFSLDLSRTKRHLVPGAHFLLQALVQEMSGSEASNVPVKVSATLVS-GSDSQVLDIQQSTNGIGQVSISFPIPPTVTELRLLVSAGSLYPAIARLTVQAPPSRGTGFLSIEPLDPRSPSVGDTFILNLQPVGIPAPTFSHYYYMIISRGQIMAMGREPRKTVTSVSVLVDHQLAPSFYFVAYFYHQGHPVANSLLINIQSRDCEGKLQLKVDGAKEYRNAD-----MMKLRIQTDSKALVALGAVDMALYAVGGRSHKPLDMSKVFEVINSYNVGCGPGGGDDALQVFQDAGLAFSDGDRLTQTREDLSCPKEK-KSRQKRNVNFQKAVSEKLGQYSSPDAKRCCQDGMTKLPMKRTCEQRAARVPQQ---ACREPFLSCCKFAEDLRR-NQTRSQAHLARNNHNMLQEEDLIDEDDILVRTSFPENWLWRVEPVDSSKLLTVWLPDSMTTWEIHGVSLSKSKGLCVAKPTRVRVFRKFHLHLRLPISIRRFEQFELRPVLYNYLNDDVAVSVHVTPVEGLCLAGGGMMAQQVTVPAG--SARPVAFSVVPTAAANVPLKVVARG--VFDLGDAVSKILQIEKEGAIHREELVYNLDPLNNLGRTLEIPGSSDPNIVPDGDFSSLVRVTASEPLETMGSEGALSPGGVASLLRLPQGCAEQTMIYLAPTLTASNYLDRTEQWSKLSPETKDHAVDLIQKGYMRIQQFRKNDGSFGAWLHRDSSTWLTAFVLKILSLAQEQVGNS------------PEKLQETASWLLAQQLGDGSFHDPCPVIHRAMQGGLVGSDETVALTAFVVIALHHGLDVFQDDDAKQLKNRVEASITKANSFLGQKASAGLLGAHAAAITAYALTLTKASEDLRNVAHNSLMAMAEETGEHLYWGLVLGSQDKVVLRPTAPRSPTEPVPQAPALWIETTAYALLHLLLREGKGKMADKAASWLTHQGSFHGAFRSTQDTVVTLDALSAYWIASHTTEEKALNVTLSSMGRNGLKTHGLHLNNHQVKGLEEELKFSLGSTISVKVEGNSKGTLKILRTYNVLDMKNTTCQDLQIEVKVTGAVEYAWDANEDYED--YYDMPAADDPSVPLQPVTPLQLFEGRRSRRRREAPKVVEEQESRVQYTVCIWRNGKLGLSGMAIADITLLSGFHALRADLEKLTSLSDRYVSHFETDGPHVLLYFDSVPTTRECVGFGASQEVVVGLVQPSSAVLYDYYSPDHKCSVFYAAPTKSQLLATLCSGDVCQCAEGKCPRLLRSLERRVEDKDGYRMRFACYYPRVEYGFTVKVLREDGRAAFRLFESKITQVLHFRKDTMASIGQTRNFLSRASCRLRLEPNKEYLIMGMDGETSDNKGDPQYLLDSNTWIEEMPSEQMCKSTRHRAACFQLKDFLMEFSSRGCQV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB13A3K7-1", "uniprot_id": "A0AB13A3K7_DANRE", "id": "A0AB13A3K7-1", "name": "", "aln": "MEEQIRPLLYLLLCMSCAVQGNSNQRFLITAPSVFHVGVKEPIVIQVGEALVGKPVS----CQLETETRVPMSAKETKTIHQKGKFETVNLEIFANTVS----------NLKSINGEPPYLNLACEVDGQRQQTRVLVSKHNGYIFIQTDQPIYNPTQKVRFRIFTLDHSMRPKLEMYVYVSIYNADGNKVKKSKYRVLDGILSKDYKIPDVSKPGVWKITAHYEDDVDNAAVREFKVQKFVLPSFGVSVHSEKAFLQAN---AKTLTFTIQASYSYGKTIDGGFHCRFGIKKGKSENDPEIEFIKGLEKTGSVKEGLAKITVNISDITQKLDTALEELATTQ-TQFYISATVTDILSGEVQESE-TFLPVVLSRYNVDLSRTRLFYTPAFPLQAVVTVRHPNGSPAEGVQVKLDVSNSK----EKSTIVTTNKEGIAFYSFNLDGKPPSVLVQATVDN-------AKSIRAVHPMKSTSFLYMSVTN-KVLSSGQFLEVSFYPKGN--PEDGQIYYMIVSRGMLRSTGSVASGSEVKKSIQIHPNMTPSFRLIAFYYIKEGDIIADSVWVDVEDTCDGEFEVKLHHNYGNHNYEPESTAELDIDVGQQKNAKVALQVVDKAIYALG--AQNKLTQKQVFASMKSYDLGCSYGGGENTAAVFNDAGLAFISHSTTIRSAMRKGFSCESGFRRNKREIDVQAEMARKEAAFKKTELQKCCRHGFTLIPMKFTCDERAKRVSKTESKDCVNAFRECCEFATKLRDKKRREDMRTGHGRTINSNEVEEFFDFEIQNIRHYFPPSFEFKQIDVKGKVRHRIHLPHSITTWEIQALSLSPSHGFCVAEPVDLTAFKPVFISLRLPYSVKRYEQLSIVAVIFNYGKMEMELVVRMRQVDGLCSPGSATSSSSVRFSLKPASSQTVTFPAVPMVKGEIPITIAIYDIEEKIEVDAIQKILLVKNEGVEMREELTYLINLDGRSDHRLSINGFFPNNTVPETDVNLFVKLEEEIFAQSTAVP-LLSSSKVENLIQAPKGCGEQTMIFMSPTALSIRYLDKSQRWLELEAGSRDKALDFIEQAYERILTFKKTDGSYGAWIQTPTSTWLTALVVKVLSLVAERQIETRQQHGTTERMISQEDIRQAVTYLIKTQRSDGSFTDAHPVYHREMQGGIGGVEQDASLTAFITIALCRSMPFLDQEAT-----AVSQSIARATNFLLKRVDN-LKRPYALAITAYCLSTCLTERTQALSAWKKLQSLGKPEGDCLVWQDDDDVR-------LVNEAKSNRVPHRVALKVETTAYALLTALAHS-DLKTAQSAVCFLSSQENYEGGFKSTQDTIVALEALSEYALSLPETPITTINAQFTVTGRSEMEKMNLEKSEN---KVEAELKRLVGQEINVNLSGKGKAKMKVAKAYYTLKED-GNCADLSINVTVVGKVEYTSVVQEDYNYYEDYGQAEETN-EEEDLPRSAIEWFDAR-SRQKRETSKNTKED---VVYTVCVSHTQGRKLSGMAIADITLLSGFEAINTDLEKLKGLVDKYISHYEVTRGRVLLYFNEIDGGEACIAFGAEQSVPIGLVQPAPALFYDYYEPDRRCSVLYSAPKRSKMVSVLCSDDVCQCAERGCFTEKKTIEMEITKTD--RFDYACYHSNTDYAFEVTVNSVTEESNFILYSTSVNVVLRNTGDLSVSPENTRVFAKRKHCKGELKQGERYLIMGNDGPTKDSSGNMQYLLDSKTWVEQKLSKSVCQASVKRKYCKELNDFLKEYQVNGCNL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * * * . . .: *:*: :***.::*. .: :*: :. *: *. : . . *.* .: . .* : *:: : . .: ...*:*. : : * .:*.*.:.*::*:********* *:**:*:*:**:.***. : . : : *:.* :* *.: .*:.. : ***:*:**.***:*::.*.::. .*:*:*:***.* *.: . *.:: . : : :** * ***.::* : **.: . ..:. *::***. .: :* ::*::. :: * . : : ::* :.:: : .**::*:* * .* * :.:***:*: . .*. : . *:. .** *..: **:..: . : . ..:* . *: : . :: *. *: . * ...** :. : : *: : :.: . * . .: ****:*** : . . : .. *: :. :::*** ::*::* : . *:*::::.:. :* : :.: : :. * *** .:* *:** * ::: * :** ::**::**. ***:.: **: ***** . . : . . *. *:**:::.* : .* . : .. ::**:.*.* :** :*::** ** : * :.* .**:** .** .: .. : : *:::* : :* ** .: :: *. : **.*:*****:.:*** ::*:*** *. : .*: ..: **** *::*:**:.: .*::** . :: : *:: *:*** .*.. :..* .. *::.*:*..** . :.:.:. . **:.*:* :::**. ***:.* :: .. .: *.* * * :*: *.. *:: . :: . **.. * .*:: *:**.*****:::** : .***::::* * . ::*:*:*:*::.: ** *:* ***:.**: :******:*:*:***. *: : *.:::: :*: * **** * ** .* ****: * :: .:****:.*** :.: .:::: : *. **::*..** ::.. * .:* *****.*: : * :.* ::.: *: * * . : . . :: :*: ** :*****.** * :. . : *:.. :*: * .:.*.*:*****:::*:*** * :: * :*. :: **. :. *. .:. :* **: :*. *.*:: *:.*..:*: ::* .*. . .* ** *:*.* * ***: .:***: . : . * :.:: *:.* .*::**:.* ..*: * ****: :. ********:******.*:.:*****..* *:*:**:*. :*****:.: . *:.* * *.* :*****:.* :****.*:::***:*.**.:*::::.*** :****** * :::* : . * *: :***:...:*.* *.* .: * *:.:.:. **: * .: : * * * *: .*: .:.***** ** * * .*. ******::*:*: *: :*::: :* * :*:*** *: .**::", "identical_positions": 509, "similar_positions": 622, "identity": "28.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100805-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M807-1", "uniprot_id": "RNF5_RAT", "id": "Q5M807-1", "name": "E3 ubiquitin-protein ligase RNF5", "aln": "----------------------------------------------------------------MAAAEEE----------------DGGPEGP---------------------NRERGGASATFECNICLETAREAVVSVCGHLYCWPCLHQWLETRPDRQECPVCKAGISREKVVPLYGRGSQKPQDPRLKTPPRPQGQRPAPESRGGFQPFGDAGGFHFSFGVGAFPFGFFTTVFNAHEPFRRG---AGVDLGQGHPASS---WQDSLFLFLAIFFFFWLLSI-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35445-1", "uniprot_id": "RNF5_MOUSE", "id": "O35445-1", "name": "E3 ubiquitin-protein ligase RNF5", "aln": "----------------------------------------------------------------MAAAEEE----------------DGGPEGP---------------------NRERGGASATFECNICLETAREAVVSVCGHLYCWPCLHQWLETRPDRQECPVCKAGISREKVVPLYGRGSQKPQDPRLKTPPRPQGQRPAPESRGGFQPFGDAGGFHFSFGVGAFPFGFFTTVFNAHEPFRRG---AGVDLGQGHPASS---WQDSLFLFLAIFFFFWLLSI-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99942-1", "uniprot_id": "RNF5_HUMAN", "id": "Q99942-1", "name": "E3 ubiquitin-protein ligase RNF5", "aln": "----------------------------------------------------------------MAAAEEE----------------DGGPEGP---------------------NRERGGAGATFECNICLETAREAVVSVCGHLYCWPCLHQWLETRPERQECPVCKAGISREKVVPLYGRGSQKPQDPRLKTPPRPQGQRPAPESRGGFQPFGDTGGFHFSFGVGAFPFGFFTTVFNAHEPFRRG---TGVDLGQGHPASS---WQDSLFLFLAIFFFFWLLSI-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RFK9-1", "uniprot_id": "A0A8M1RFK9_DANRE", "id": "A0A8M1RFK9-1", "name": "E3 ubiquitin-protein ligase RNF185", "aln": "----------------------------------------------------------------MEAAEQQRSSSDGAAARGAGFPGSGGGAGPGGG-----------------AEGERDRERATFECNICLDTARDAVISLCGHLFCWPCLHQWLETRPSRQQCPVCKAGISRDKVIPLYGRGSSSQEDPRLKTPPRPQGQRSEPESRGPFQGFGDTG-FHMSFGIGAFPFGFFTTVFNTNNPFHRADAHYGADQQANENANNGNNWQDSLFLFLAIFFFFWILSV-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IR26-1", "uniprot_id": "Q8IR26_DROME", "id": "Q8IR26-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MEEPKSVSTAELPSTSTGASSSSSTLSNNVSYDKIAWTRDITEPLAEESSTSQLRPLGTSIPTNSTASELKKSNTSYSFTG---DYLSGGNKADLKGGYPFGGTDTDTKANEKDKEKEHTADDSLYECNICLDTAKDAVVSMCGHLFCWPCLHQWLLTRPNRKLCPVCKAAVDKDKVIPLYGRNSTHQEDPRNKVPPRPAGQRTEPDPVPGFPGFGFGDGFHMSFGIGAFPFGFITSRLNFFEP--RP----PADIRRLHEDEP--WALSKLFWHFVVFVIYGLLVPIVHGSSR", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8IQM1-1", "uniprot_id": "Q8IQM1_DROME", "id": "Q8IQM1-1", "name": "RING-type E3 ubiquitin transferase", "aln": "----------------------------------------------------------------MSADTFV----------------------------------------------MDTKDESFYECNICLDTAQNAVVSMCGHLFCWPCLYQWILTKPDHTVCPVCKSGVDRSKVIPVYARNDKRQEDPRDKTPPRPTGIWSDYANDLELGLF-----SYLLFGL-FFPYGALSSYLDMDEPLNPA-----ADHGIRDGQNE--TLLSKFFLYVAIMLIIYMIVI-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : :******:**::**:*:****:*****:**: *:*.: *****:.:.:.**:*:*.*.. :*** *.**** * . : * :: **: **:* ::: :: :* .* . . ..:* ...::.: :: ", "identical_positions": 53, "similar_positions": 53, "identity": "18.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100805-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18910-1", "uniprot_id": "ANPRA_RAT", "id": "P18910-1", "name": "Atrial natriuretic peptide receptor 1", "aln": "MPGSRR---VRPRLRALLLLPP-LLLLRG---------------------------GHASDLTVAVVLPLTNTSYPWSWAR------------VGPAVELA------LARVKARPDLLPGWTVRMVLGSSE-------NAAGVCSDTAAPLAAVDLKWEHSPA-VFLGPGCVYSAAPVGRFTAHWRVPLLTAGAPALGIGVK-DEYALTTR-TGPSHVKLGDFVTALHRRLGWEHQALVLYAD--RLGDDRPCFFIVEGLYMRVRERLNITVNHQEFVEGD--PDHYPKLLRAVRRKGRVIYICSSPDAFRNLMLLALNAGLTGE-DYVFFHLDVFGQSLKSAQGLVPQKPWERGDGQDR---SARQAFQAAKIITYKEPDNPEYLEFLKQLKLLADKKFNFTVEDG-LKNIIPASFHDGLLLYVQAVTETLAQGGTVTD----GENITQRMWNRSFQGVTGYLKIDRNGDRDTDFSLWDMDPE-TGAFRVVLNYNGTSQELMAVSEHKLYWPLGYPPPDVPKCGFDNEDPACNQDHFSTLEVLALVGSLSLISFLIVSFFIYRKMQLEKELVSELWRVRWEDLQP-SSLERHLRSAGSRLTLSGRGSNYG--SLLTTEGQFQVFAKTAYYKGNLVAVKRVNRKRIE--LTRKVLFELKHMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKITDYGLESFR----DPEPEQG----HTLFAKKLWTAPELLRMASP-PARGSQAGDVYSFGIILQEIALRSGVFYVEG--LDLSPKEIIERVT----RGEQPPFRPSMDLQS-HLEELGQLMQRCWAEDPQERPPFQQIRLALRKFNKENSS-NILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGQLHAREVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFDGFELELRGDVEMKGKGKVRTYWLLGERGCSTRG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P18293-1", "uniprot_id": "ANPRA_MOUSE", "id": "P18293-1", "name": "Atrial natriuretic peptide receptor 1", "aln": "MPGSRR---VRPRLRALLLLPP-LLLLRS---------------------------GHASDLTVAVVLPLTNTSYPWSWAR------------VGPAVELA------LGRVKARPDLLPGWTVRMVLGSSE-------NAAGVCSDTAAPLAAVDLKWEHSPA-VFLGPGCVYSAAPVGRFTAHWRVPLLTAGAPALGIGVK-DEYALTTR-TGPSHVKLGDFVTALHRRLGWEHQALVLYAD--RLGDDRPCFFIVEGLYMRVRERLNITVNHQEFVEGD--PDHYTKLLRTVQRKGRVIYICSSPDAFRNLMLLALDAGLTGE-DYVFFHLDVFGQSLQGAQGPVPRKPWERDDGQDR---RARQAFQAAKIITYKEPDNPEYLEFLKQLKLLADKKFNFTMEDG-LKNIIPASFHDGLLLYVQAVTETLAQGGTVTD----GENITQRMWNRSFQGVTGYLKIDRNGDRDTDFSLWDMDPE-TGAFRVVLNFNGTSQELMAVSEHRLYWPLGYPPPDIPKCGFDNEDPACNQDHFSTLEVLALVGSLSLVSFLIVSFFIYRKMQLEKELVSELWRVRWEDLQP-SSLERHLRSAGSRLTLSGRGSNYG--SLLTTEGQFQVFAKTAYYKGNLVAVKRVNRKRIE--LTRKVLFELKHMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAIGSHGNLKSSNCVVDGRFVLKITDYGLESFR----DPEPEQG----HTLFAKKLWTAPELLRMASP-PARGSQAGDVYSFGIILQEIALRSGVFYVEG--LDLSPKEIIERVT----RGEQPPFRPSMDLQS-HLEELGQLMQRCWAEDPQERPPFQQIRLALRKFNKENSS-NILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGQLHAREVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALRIHLSSETKAVLEEFDGFELELRGDVEMKGKGKVRTYWLLGERGCSTRG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16066-1", "uniprot_id": "ANPRA_HUMAN", "id": "P16066-1", "name": "Atrial natriuretic peptide receptor 1", "aln": "MPGPRRPAGSRLRLLLLLLLPPLLLLLRG---------------------------SHAGNLTVAVVLPLANTSYPWSWAR------------VGPAVELA------LAQVKARPDLLPGWTVRTVLGSSE-------NALGVCSDTAAPLAAVDLKWEHNPA-VFLGPGCVYAAAPVGRFTAHWRVPLLTAGAPALGFGVK-DEYALTTR-AGPSYAKLGDFVAALHRRLGWERQALMLYAY--RPGDEEHCFFLVEGLFMRVRDRLNITVDHLEFAEDD--LSHYTRLLRTMPRKGRVIYICSSPDAFRTLMLLALEAGLCGE-DYVFFHLDIFGQSLQGGQGPAPRRPWERGDGQDV---SARQAFQAAKIITYKDPDNPEYLEFLKQLKHLAYEQFNFTMEDG-LVNTIPASFHDGLLLYIQAVTETLAHGGTVTD----GENITQRMWNRSFQGVTGYLKIDSSGDRETDFSLWDMDPE-NGAFRVVLNYNGTSQELVAVSGRKLNWPLGYPPPDIPKCGFDNEDPACNQDHLSTLEVLALVGSLSLLGILIVSFFIYRKMQLEKELASELWRVRWEDVEP-SSLERHLRSAGSRLTLSGRGSNYG--SLLTTEGQFQVFAKTAYYKGNLVAVKRVNRKRIE--LTRKVLFELKHMRDVQNEHLTRFVGACTDPPNICILTEYCPRGSLQDILENESITLDWMFRYSLTNDIVKGMLFLHNGAICSHGNLKSSNCVVDGRFVLKITDYGLESFR----DLDPEQG----HTVYAKKLWTAPELLRMASP-PVRGSQAGDVYSFGIILQEIALRSGVFHVEG--LDLSPKEIIERVT----RGEQPPFRPSLALQS-HLEELGLLMQRCWAEDPQERPPFQQIRLTLRKFNRENSS-NILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTALSAESTPMQVVTLLNDLYTCFDAVIDNFDVYKVETIGDAYMVVSGLPVRNGRLHACEVARMALALLDAVRSFRIRHRPQEQLRLRIGIHTGPVCAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHLSSETKAVLEEFGGFELELRGDVEMKGKGKVRTYWLLGERGSSTRG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQN2-1", "uniprot_id": "A0A8M3AQN2_DANRE", "id": "A0A8M3AQN2-1", "name": "Guanylate cyclase", "aln": "MSLLLCFSESRFFLLPLLLLCCGTLSTWTKISKHQGS--------------HKGAHNHSNDIVLAVILPQHNTSYPWAWPR------------VGPALDRA------IARVNANPNLLPRHRVRHVFANSE-------DRDGICSESMAPLMAVDLKFEHNPW-AFIGPGCDYTSSPVGLFTAHWGLPMITAGAPAVAFLQM-EIYTSITN-TGPTHKKLGEYALHLYRHFGWNQHSLLMFSD--TKMGERACYFALEGLYTEMHEEN-ITTMDLVFEENKG-PVNYSELLHKIQGDGRVVFVCCSPDVFRQLIVHFHKAGLPKE-EYVFFYIDIFGHSFRSR----PSQPWARGDSDDV---FAKEAFQSVKILTYLEPQNQEYKDFVTDLKSDAKRMFNFTVDDS-LMNIISGGFYDGLMLYCHALNESLSDSHERPS----GESVSKRMWNRTYYGVTGLVQIDENGDRETDFALWDMADINTGDFQIVAVYNGTQKEMNILPGMAIQWPGGKVPMDVPTCGFKNENPACRARTIAMHQMISIVLFLILIIIFTVTVFIYRKLKLEKELVAQLWRISWDDIQM-SHLEKALRSTGSKLTLSLRGSNYG--SLLTTDGNFQVFAKTGYFKGNIVAIKYINRRRVE--LTRKVLFELKHMRDVQNEHLTRFIGACIDPPNICIVTEYCPRGSLQNILENDSITLDWMFKYSLISDIVKGMAFLHNSVIVSHGNLKSSNCVVDNRFVLKITDYGLSSIRT---ESDTEDA----HSYYARKLWLAPELSRMECF-PPGGTQKGDVYSFGIILQEVALRRGVFYLEG--DLLSPKEIVDRVA----LGEWPYLRPSLNPQA-HSEELGQLMQRCWAEEPSDRPEFSHISVLLRKQNREHRS-NILDNLLSRMEQYANNLEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTSLSAESTPLQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHGREIARMSLALLEAVKTFKIRHRPDEQLKLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTSSRMESNGEPLKIHVSSATRAVLQEFNCFQLELRGDVEMKGKGKMRTYWLLGEVKAGD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VF17-1", "uniprot_id": "Q9VF17_DROME", "id": "Q9VF17-1", "name": "Guanylate cyclase", "aln": "MPQAGQG---LSLLLILCLLQAHLFPSAAWFYDAESVGGVASIGVGSDEHSFKTPETKNSHKSQSTELVQHFPSLPMPDHRRLGARRQLVFVALLPSVESDNKNDCIMPKVLPVLELAIRHVQRMGFVGGSHFDIQLISRDTFCSSKYGPIGFFEIYTQWPEVNAVFGLPCEYVLAPISRYADVWQVPVLTTGGNAKEFNKKSESYSTLTRLKGAQVNNLGNVVRAILNSFNWTRTALIYQNENAKVKGNSVCFLCLAAIHDTIEEHS---VYQLGFDTSTWTKADITRMLKNVAMQSRIVIMCADPQSIRQIMLTAEELNMIDSGEYVFINIELFSRVQYLT-----SQPWYDKNDTDLNNERAQKAYTAMLTVTPKQPNDNEYTRVSNEIKAIAAEKYNYTFSDNEPISAFVTSFFDGVLLYANALNESIREDPTMLTRPINGTDMVRRMWNRSFTGITGNVTIDANGDRLSAYSLLDMNPT-TGRFEIVAHFLHNRLEFEANKEIHWAGDREEAPPDRPICGYDG--ALCPDNSLPGYAILSIVLGTMVVVMAVCFFFGYRHYIAEAEINSMSWKVSLEDVMFRDAAERGLRGSFHSLVKQSSQLTLMSEDMVSINGDRQIFIPVGMFRKSKVAIKPVEVDNVQGLLTRSLMLELKRMKDLQHDHLVKFYGACLDQRRSFLLTEYCPKGSLQDILENEQFQLDWMFRLSLMHDIVRGMQFLHSSDIRSHGNLKSSNCVVDSRFVLKITDFGLHTLRRTRFDLESDGGNCNSHAYWSKLLWTAPELLRVEHNRPPEGTQKGDVYAFGIIVHEITTRQGPFYLGRCAYEKSPQEIIELVKGYNPHRMQKPFRPELEPNGDTKADINGIIRRCWAEDPAERPDFNTLKSMIRRFNKDNETGNIVDNLLKRMELYANNLEELVEERTQDYHEEKKKCEKLLYQLLPQSVAAQLISGQPVVAETFDQVTIYFSDIVGFTAISAESTPMQVVQFLNDLYTCFDSIVENFDVYKVETIGDAYMVVSGLPIRNGNQHAREIARLALALLEAVHNFRIHHRPEDRLKLRIGLHTGACVAGVVGLKMPRYCLFGDTVNTASRMESNGEALKIHISETTKEALDEFGTFVTTRRGFVPMKGKGEMLTYWLEGEVPRPNSLISPSKLMLTRRSSLKQPQRSQSHNLHKQYSELVVASPPPQLPPPAIALPPPPSPSKDSPNLRVKRKISSSSPKLNGGGFDYHKTENHYLDTAAAAQRNCDIYSSRSLRDMEETSDSWELAHFRLPLSGALKSHHHLNNNSHGYVHSNSSSNLSGILQPPPLGVQRTRLKPSPTISTLLTSARSEANASPGPETGSMGSGQLRIKFAEGDETPLLPTPPPLAAPPPIPQMVAASPQRSGSGQNIPADSSHYGFLVKSYKQQCPPVAGSAVTQPLLAKINS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. * * ** : : .. :. * .* * . * : *::: : :* . :* * : ... . .**.. .*: .:: : ..:* * * :*:. :: * :*::*:*. * : : *: *. *. :**: . : . :.* : :*: .: *:: : .:. :.:. . . * . . ..:*: : ..*:: :*..*: :* ::: . .: . :***: :::*.: :** :. * *::*: : :* :*:: ** . .::* * . :*:*..*. . : .*.**::** :*:.*:: .. * .: :*****:: *:** : ** .*** : ::* ** .* *.:* : . *: * * * **:.. . * :. ::::* :: : .* **: * *: : *:: :*: . *: **.: *. . . .::: :*: *:* .. :: . **:* :: .:: ***.:::***:*:*:*::**.:* *** * . ::*****:****:****:.: *****: ** ***:** ***.. * *************.********:** ::* : :.: . *: ::: ** **** *: * *:* ****:****::*:: * * *:: **:**:: * :**.: :. ::. :::*****:* :** *. : :*: *::: : **:****.*** ************** * ***:*.* ****:**:*** ** *:.* **:**.************::******:*** :*********::::*********************:***. *. *:**::****:**:.*:*:***:::*:****:*:*. ********************:********.*:**:*. *: .*:**. * ** * *****:: **** ** ", "identical_positions": 392, "similar_positions": 316, "identity": "27.39%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100806-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BK61-1", "uniprot_id": "SNX20_RAT", "id": "Q5BK61-1", "name": "Sorting nexin-20", "aln": "MASPQHPGGPGWTGPRNQCITRTRQEVLPPGPDLPCPGPE---EAQDGPTSNSNMTTRELQEHWQKEKSRWKHVRLLFEIASARIEERKVSKFVMYQVVVIQTGSFDSDK-AVVERRYSDFERLQRALLKRFGPELEDVTFPRKRLTGNLSAETICERRLELREYLRLLYAVRAVRRSREFADFLTRPELCEAFGCLRAGQYARALDLLGRVVPLQEKLTAHCPSAPVPALCAMLVCLRDLERPAEAFA----VGERALRRLGARESHRYYAPLLDAMVRLAYALGKDLASLQGRLD-ESQLRRPTHRGATLKELTVREYLS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D2Y5-1", "uniprot_id": "SNX20_MOUSE", "id": "Q9D2Y5-1", "name": "Sorting nexin-20", "aln": "MASPEHPGSPGWRGPINQCRTRTRQEVLPPGPDLPCPGPE---EAQDGPSSNSSMTTRELQEHWQKEKSRWKHVRLLFEIASARIEERKVSKFVMYQVVVIQTGSFDSDK-AVVERRYSDFERLQKALLKRFGPELEDVTFPRKRLTGNLSAETICERRRELREYLRLLYAVRAVRRSREFLDFLTRPELREAFGCLRAGQYARALELLGRALPLQEKLTAHCPSAAVPALCAALVCLRDLERPAEAFA----VGERALRCLRTRENHRYYAPLLDAMVRLAYALGKDFAALQSRLD-ENQLRRPTHRDATLKELTVREYLS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z614-1", "uniprot_id": "SNX20_HUMAN", "id": "Q7Z614-1", "name": "Sorting nexin-20", "aln": "MASPEHPGSPGCMGPITQCTARTQQEAPATGPDLPHPGPDGHLDTHSGLSSNSSMTTRELQQYWQNQKCRWKHVKLLFEIASARIEERKVSKFVVYQIIVIQTGSFDNNK-AVLERRYSDFAKLQKALLKTFREEIEDVEFPRKHLTGNFAEEMICERRRALQEYLGLLYAIRCVRRSREFLDFLTRPELREAFGCLRAGQYPRALELLLRVLPLQEKLTAHCPAAAVPALCAVLLCHRDLDRPAEAFA----AGERALQRLQAREGHRYYAPLLDAMVRLAYALGKDFVTLQERLE-ESQLRRPTPRGITLKELTVREYLH----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BA68-1", "uniprot_id": "A0A8M2BA68_DANRE", "id": "A0A8M2BA68-1", "name": "", "aln": "MEEEEKPPNT----TANHTVSSAPEHLSPHQETLQGNGES---AEDDLCFGASCLTTAELQQHWRAVKQEFRSVKLLFDIPSARIISQTISKHVVYQVVVIRSGSYDCER-VAIERRYSDFLHLHQELLSDFSEELEDVVFPKKKMTRNFSEEIIAERRVALRDYLTQLYSLRFVRKSQAFQSFFTHQELKSAYDLLRGGRFSRALEGLQKVLVLQEKLSSHDATLVIPTLCAILVCQRDLEDFEAAFE----TGRKALPTVRRYELRKHHGPLLEALVDLGFSLELPVAQLQDELIRVNDSPCGKETQMSLKELVVQEFV-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQG1-1", "uniprot_id": "Q9VQG1_DROME", "id": "Q9VQG1-1", "name": "", "aln": "MPIHAVMAKRLHHQPTFDGDPPGPDELDSPAIEAAALDIPPPESDKALQKGVWERATSAEYKPTTDGSTVLRFDILLAHIMPPDGEDVKIKRFVVYELTVKQDGATEDTQPAKIERRYTDFRELYLGLKRQHPAEMANKYFPAKVLMGNFKSELIGERSAAFEAFLTYVASQAMLRDSEYFLRFLQHDELTRACQFLDERRNEMAIPILENCFRLLNKIYMNRSRPVLLILCRLVAACTSSPVPHHAAERWALLALSRFETLCDIDLLPLYIPLLHTCAHLWWQRGQDQKPITDRLTDMSKQGINTANTESLMQAIHKIDPRTETI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . . :. . . . . :* : . : ** .* .. . .:.:.*:*:: * : *: : : . :****:** .* * . *: : ** * : *: * * ** :. :* : : :* *. * *: : ** * * : *: * . . * :*: : . : ** : . . * . : : : : ***.: . * : : .* .. . :* : : ", "identical_positions": 48, "similar_positions": 76, "identity": "14.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100809-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DC53-1", "uniprot_id": "CPNE8_MOUSE", "id": "Q9DC53-1", "name": "Copine-8", "aln": "MWARDKCSVPQLEMDSRYTSATGIGDLNQLSAAIPATRVEVSVSCRNLLDRDTFSKSDPICVLYTQAVGNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIVGIPGRKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIKP--------SPAPPPYTPPTHVLQTQI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86YQ8-1", "uniprot_id": "CPNE8_HUMAN", "id": "Q86YQ8-1", "name": "Copine-8", "aln": "-------------MDSRYNSTAGIGDLNQLSAAIPATRVEVSVSCRNLLDRDTFSKSDPICVLYVQGVGNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIVGIPGKKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELSRGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIKP--------SPAPPPYTPPTHVLQTQI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F5X2-1", "uniprot_id": "E7F5X2_DANRE", "id": "E7F5X2-1", "name": "Copine-8", "aln": "----------MSTLTGGFLNMASLADFEPLAAVIPATKVEITVSCRNLLDRDTFSKSDPICVLYTQTVANREWREFGRTEVIDNTLNPDFVHKFILDYFFEERQNLRFDLYDLDSKSENLSKHDFLGQMYCTLGEVVGSPGSRMERSLIGIPGKNCGTVIVKAEELGNCRESVLMQFCGNKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLDPVWQAFKIPVRALCNGDYDRAIKIEVYDWDRDGGHDYIGEFSTSYRELSKGHTQFTVWEVLNPKKKKKKKKYLNSGTVTLLSCFIDVEVTFLDYIKGGTQINFTVAIDFTASNGNPSQPTSLHYMSPYHLNAYALALRAVGEIIQDYDSDKLFPALGFGAKLPPDGRVSHEFPLNGNPDNPYCSGIEGVLEAYYQSLKSVRLYGPTYFSPVINHVARYASLVKDGSEYFILLIISDGVISDMAQTKESIVNASSLPMSIIIVGVGPAEFDEMIELDGDEVRISSRGRFAERDIVQFVPFRDYIDRRGNHILSMARLAKDVLAEIPDQFLQYVRSRGIKPQHSAHSTISKPPASLVHPIHHLQTQI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . :.:.*:: *:*.****:**::**********************.* *.*:********************:***********:********:**** **********::*****:*** ***:*:.::****::***:*:.****. **::******.*************************:**************:********.***********:**:*********.**:****:******::*::**.*:**:***** ***** ********* :::.**:**************************:********.**:****.:**:*****:*******:***************:****.*****:****.*****:****:*****:***** *:*********** *****:**:***::******************.**************** *:*****:**:****::***************** *******************:***.*:*:***** * .*.. . * * *****", "identical_positions": 451, "similar_positions": 92, "identity": "77.09%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100811-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P54753-1", "uniprot_id": "EPHB3_HUMAN", "id": "P54753-1", "name": "Ephrin type-B receptor 3", "aln": "MARARPPPPPSPPPGLLPLLPPLLLLPLLLLPAGCRALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGFIWRRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAGRVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHG---AGGASACSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEG--IASTVTSQMNSVQLDGLRPDARYVVQVRARTVAGYGQYSRPAEFETTSERGSGAQQLQEQLPLIVGSATAGLVFVVAVVVIAIVCLRKQRHGSDSEYTEKLQQY----IAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAG-----------------------------EFGEVCRGRLKQPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVIASAQSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVSAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILSSIQDMRLQMNQTLPVQV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P54754-1", "uniprot_id": "EPHB3_MOUSE", "id": "P54754-1", "name": "Ephrin type-B receptor 3", "aln": "MAGARPPP------GLLPLLAPLLLP--LLLPAGCWALEETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGFIWRREVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVDTIAPDESFSRLDAGRVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFYKKCASTTAGFALFPETLTGAEPTSLVIAPGTCIANAVEVSVPLKLYCNGDGEWMVPVGACTCATGHEPAAKESQCRACPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDSADSACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCRGSSGAGGPATCSRCDDNVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPSEVPTLHLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSKG--IASTVTSQKNSVQLDGLQPDARYVVQVRARTVAGYGQYSHPAEFETTSERGSGAQQLQEQLPLIVGSTVAGFVFMVVVVVIALVCLRKQRHGPDAEYTEKLQQY----IAPGMKVYIDPFTYEDPNEAVREFAKEIDVSCVKIEEVIGAG-----------------------------EFGEVCRGRLKLPGRREVFVAIKTLKVGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMILTEFMENCALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSEMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPSDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVRDRNLRPKFSQIVNTLDKLIRNAASLKVTASAPSGMSQPLLDRTVPDYTTFTTVGDWLDAIKMGRYKESFVGAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILCSIQDMRLQMNQTLPVQV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58IDQ0-1", "uniprot_id": "A0AC58IDQ0_DANRE", "id": "A0AC58IDQ0-1", "name": "Ephrin type-B receptor 3", "aln": "-----------------MTMDYLLFLCGFLLPLSS-AVEETLMDTKWAMTELAWTSHPETGWEEVSGYDDAMNPIRTYQVCNVRELNQNNWLRSDFIPRKDVLRVYVEMKFTVRDCNSIPNIPGSCKETFNLFYYESDSDSATATSPFWMENPYVKVDTIAPDESFSMLESGRVNTKIRSFGPLSKAGFYLAFQDLGACMSLISVRAFYKKCSTTIANFAVFPETATGAEATSLVIAPGTCVPNALEVSVPLKLYCNGDGEWMVPVGSCTCMAGFEPAVKETQCQACSPGTFKSKQGEGLCSPCPPNSRTSSGAASICSCRTGYYRADSDSPDSGCTTVPSAPRNVISSVNETSLILEWSEPRDQGGREDLLYNVICKKCLP-----ERGTCTRCDDNVDISPRHLGLTERHVTIRNLQAHTQYSFEIQAVNGVASKSPYAPQFASVNITTNQAAPSAVPTVHLTGASANTMTLSWLPPEKPNGIILDYEIKYHEKDQGEAIAHTMTAQHSYARIDGLKPGTPYVVQVRARTVAGYGRYSSPTDFGTN-HQADADKALQEQLPLIVGSLTAGLVFIIVVVVIAIVCLRKQRNGSESEYTEKLQQYKSPIVTPGMKVYIDPFTYEDPNEAIREFAKEIDVSCVKIEEVIGAGNQHQKLLSNRGKTARHTQAIPLEDFTSSGEFGEVCRGRLKLPGRREIIVAIKTLKAGYTERQRRDFLSEASIMGQFDHPNIIRLEGVVTKSRPVMIVTEFMENGALDSFLRLNDGQFTVIQLVGMLRGIAAGMKYLSDMNYVHRDLAARNILVNSNLVCKVSDFGLSRFLEDDPTDPTYTSSLGGKIPIRWTAPEAIAYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVINAVEQDYRLPPPMDCPTALHQLMLDCWVKERNLRPKFSQIVNTLDKLIRNAASLKVVTSTHSGASQPLLDRCVPDYTTFTTVGDWLDAIKMSRYRDNFLNAGFASFDLVAQMTAEDLLRIGVTLAGHQKKILGSIQDMRLQMNQTLPVQV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **: :*** .. *:*********. :*********:*********:*************** .******:.** *::* *****:***************************:*** *:*:********************** *::******:***************** ****************::* *.**:**** ****.**********:.**:*********************:*** :*.***.**:**:.*.**::*:***** * ********:* *****:*:..:*******.**.******.**.***.*************** ***:*********** .:*:******:: **:******:* * :* ***:*:**:******:.*** .*::*:*********** ***::* .:*..::**** ***:***:*****:**.**.:* ** *:*:* . .::***:*.: **************:** *::* *. .:... : *********** .**:**::.*****:*******:*.::********* ::******************:********************* *********** *****::*******.****************************************:****** *********************************:************************************:****************************************************************************************::************************** :*: ** ******* *******************.**::.*:.******************************** *****************", "identical_positions": 795, "similar_positions": 132, "identity": "76.74%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100812-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86YR7-1", "uniprot_id": "MF2L2_HUMAN", "id": "Q86YR7-1", "name": "Probable guanine nucleotide exchange factor MCF2L2", "aln": "-----------MLSCLKEEMPPQELTRRLA----------------TVITHVDEIMQQEVRPLMAVEIIEQLHRQFAILSGGRGEDGAPIITFPEFSGFKHIPDEDFLNVMTYLTSIPSVEAASIGFIVVIDRRRDKWSSVKASLTRIAVAFPGNLQLIFILRPSRFIQRTFTDIGIKYYRNEFKTKVPIIMVNSVSDLHGYIDKSQLTRELGGTLEYRHGQWVNHRTAIENFALTLKTTAQMLQTFGSCLATAELPRSMLSTEDLLMSHTRQRDKLQDELKLLGKQGTTLLSCIQEPATKCPNSKLNLNQLENVTTMERLLVQLDETEKAFSHFWSEHHLKLNQCLQLQHFEHDFCKAKLALDNLLEEQAEFTGIGDSVMHVEQILKEHKKLEEKSQEPLEKAQLLALVGDQLIQSHHYAADAIRPRCVELRHLCDDFINGNKKKWDILGKSLEFHRQLDKVSQWCEAGIYLLASQAVDKCQSREGVDIALNDIATFLGTVKEYPLLSPKEFYNEFELLLTLDAKAKAQKVLQRLDDVQEIFHKRQVSLMKLAAKQTRPVQPVAPHPESSPKWVSSKTSQPS--TSVPLARPLRTSEEPYTETELNSRGKEDDETKFEVKSEEIFESHHERGNPELEQQARLGDLSPRR-RIIRDLLETEEIYIKEIKSIIDGYITPMDFIWLKHLIPDVLQNNKDFLFGNIRELYEFHNRTFLKELEKCAENPELLAHCFLKRKEDLQIYFKYHKNLPRARAIWQECQDCAYFGVCQRQLDHNLPLFKYLKGPSQRLIKYQMLLKGLLDFESPEDMEIDPGELGGSAKDGPKRTKDSAFSTELQQALAVIEDLIKSCELAVDLAAVTECPDDIGKLGKLLLHGPFSVWTIHKD-RYKMKDLIRFKPSQRQIYLFERGIVFCKIRMEPGD-QGLSPHYSFKKTMKLMTLSIRQLGRGSHRKFEIASRNGLEKYILQAASKEIRDCWFSEISKLLMEQQNNIKDQGNPQFEMST-----------------SKGSG-------AGSGPWIKN----------MERATTSKE----------------------------DPASSTG-----------------------------GIKGCSSREFSSMDTFEDCEGAEDMEKESS--------ALSLAGLFQ----SDDSHETCSSKSAFLERGESSQGEKEERDEE------------ETATRSTEEERAGASTGRLAPAG------ATAGFQARALRPRTSAQES-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GRY3-1", "uniprot_id": "A0AC58GRY3_DANRE", "id": "A0AC58GRY3-1", "name": "", "aln": "MNGYQTAQSRCSVCGLYSQGASFTLVRISAGEMESYHRFLGVCLETELATRRNEIMQQEIRPLLAVDIIEQLHRQFALLSGGRGQEGSPIITFPEFSGFNEVSDEDFINVVTYLTSIPSMDAASIGFIIILDRRKDKWNSAIASLARIAGSFPGNLQLVLVLKPSRFLQRAIADVSMRLHRDDFKLKVPIVMLNSLSDLHGYIDKGQLTCDLGGTLDYCHSQWIHHRTAIENFALTVKSTAQMLQQFGTDLAETELPNDVQCTKDLLITHTEKHDKLKDELKLAVKQGNTLLSCIKDQATKAESHILNPDEVENQTTVERLLAQLDETENAFEQFWSRHHLKLEQCLQLRHFEQDFKEVKVSLDGLSEALLGLSDTGDCVARVEQLLGELKTLEDKAQECLEKAQLQAQHGDQLIQSNHYAIDSIRPKCVELRRICDDFSNEAKKKRDVLTKSLEILKRIDEVNQWCESGVYLLASQAVDRCQTQEGAEAALQDIERYMKTAKEQQLSHLKELNNQYEVVLSELLKSKVQTALKTLNDVQEMFEKRHASLKKLSTKQTRPVQPVAPRPESSPKRPSPKIPHPTPPTSHRKTTDNSSTNRQPSDAELAKR-KNIRKAKGGIKIEVMHEGGQGGSSHILMNNETEESLSNRRSHIMNELIETERLYVEELQSIIEGYAAALDDPELIYLIPPSLENKKEVLFGNLPEIYQFHQKIFLKELENSAEKPELVGTCFLKRKEELQIYEKYCQNKPRSEALWRQCGDSMFFQECQKRLDHKLSLDAYLLKPVQRITKYQLMLKEMLKCS-----------------------KNPEGTAELEEAQATVLDIIKSVNDSMHQIAITGFEGSLNDLGKLLMQGSFNVWTDHKKGHSKVKDLARFKPMQRHLFLYHKMILFCKKREEMTDGHEKSPSYSFKHSLKMGSVGITENVKGDIKKFEIWYNGREEVYIIQAPSMDVKNTWVSEIRKVLTSQLEACREASQLHQKITENIYHAPMRNMRKTALRQSDSSSPETGYRRSDSGPNMRQKRADASSSLGSERAALPRKRFTLQGLSNRRSLPAEPAPKETEVTRRFSLASTVGSATAPRTKAPLSSSLKSKRHQIKSDPTPFGYEGATKTRGFKKETMRDSLPAERKSKGSGGSKPAVPRSASQPGWSQRRLPSMDAEDFETIPSSAEELSISSDGEDEGHNKNGDNDRYQVQLTYESGTAQDLSVEAGDFVQFLEESENGLWLVKNLRTQKTGLVPPTVLQSTAEELDLYSNSDIFSDLCTAALTDTEDDIGGTNPAQDGRFTC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. * .: .. *.* * : *: :******:***:**:**********:******::*:***********:.:.****:**:********::*******:::***:***.*. ***:*** :*******:::*:****:**:::*:.:: :*::** ****:*:**:*********.*** :*****:* *.**::***********:*:****** **: ** :***..: .*:***::**.::***:***** ***.******:: ***. . ** :::** **:****.******:**.:***.*****:*****:***:** :.*::**.* * ::. **.* :***:* * *.**:*:** ****** * *******:*** *:***:*****::**** * *** *:* ****: :::*:*.****:*:*********:**::**.: **:** :: *.** * **: *::*::*: *:*.*..*: *:****:*.**:.** **::***********:****** *.* .:*: ** : :::. :::** .* *: ::* :* * :.*. : .. * :: .** ** :*:.:*:***.:*::*::***:** :.:* * :*** *:*:*:.****: *:*:**:: ******:.**:***:. *******:**** ** :* **:.*:*::* *. :* **::***:*.* ** * **: ***::** :*. . *:. ::**::* *.: *:*** : ::. *:* ..:..*****::*.*.*** **. : *:*** **** **:::*:.: *:*** * * * : ** ****:::*: ::.* : :*. :**** .. * **:**.* :::: *.*** *:* .* : :: .: : ::: *..*. :.*** ::: ***: .:: . **:.* * :*.:. . . :*:.*. ** .* *. : * .* * * *:.: : *: * . **:**.* :::: *:.* . . .** . * : . * .* * * *.: ", "identical_positions": 540, "similar_positions": 337, "identity": "41.28%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100812-10", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A584-1", "uniprot_id": "D4A584_RAT", "id": "D4A584-1", "name": "Tyrosine-protein kinase", "aln": "MGFSSELCSPQGHGAVQQMQEAELRLLEGMRKWMAQRVKSDREYAGLLHHMS--LQDSGGQSWSSGPD--SPVSQSWAEITSQTENLSRVLRQHAEDLNSGPLSKLSVLIRERQHLRKTYNEQWQQLQQELTKTHSQDIEKLKSQYRTLTRDSAQARRKYQE------ASKDKDRDKAKDKYVRSLWKLFAHHNRYVLGVRAAQLHHQHYHQFMLPGLLQSLQDLHEEMAGILKDILQEYLEISSLVQDDVASIHRELAAAAARIQPEFEYLGFLRQYGSAPDVPPCVTFDVSLLEEGE-QLEPGDLQLNELTLESVQHTLTSVT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DELAVATK------------------------EVLSRQEMVSQLQRELQCEEQNTHPRERVQLLGKR----------QVLQEAMQGLQVALCNQD----------KLQAQQELLQSKME------------------QLGTGEPPAVPLLQDDRHSTSSTEQERD----GGRTPTLEIIKSHFSGIFR--PKFSIPPPLQL--------------------------------------------------------------------------------------VPEVQK-----------------------------------------------------------------------------------------------------------------------------------------PLHEQLWYHGAIPRAEVAELLTHSGDFLVRESQGKQE--YVLSVLWDGQPRHFIIQSS-DNLYRLEGDGFPSIPLLITHLLSSQQPLTKKSGVVLFRAVPKDKWVLKHEDLVLGEQIGRGNFGEVFSGRLRADNTPVAVKSCRETLPPDLKAKFLQEARILKQYNHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADGIYAASAGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPN---LTNQQTREFVEKGHRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTICQELQSIRKRHR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16879-1", "uniprot_id": "FES_MOUSE", "id": "P16879-1", "name": "Tyrosine-protein kinase Fes/Fps", "aln": "MGFSSELCSPQGHGAVQQMQEAELRLLEGMRKWMAQRVKSDREYAGLLHHMS--LQDSGGQSWSSGPD--SPVSQSWAEITSQTENLSRVLRQHAEDLNSGPLSKLSVLIRERQHLRKTYNEQWQQLQQELTKTHSQDIEKLKTQYRTLVRDSTQARRKYQE------ASKDKDRDKAKDKYVRSLWKLFAHHNRYVLGVRAAQLHHHHHHRFMLPGLLQSLQDLHEEMAGILKDILQEYLEISSLVQDDVASIHRELAAAAARIQPEFEYLGFLRQYGSTPDVPPCVTFDESLLEDGE-QLEPGELQLNELTLESVQHTLTSVT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DELAVATK------------------------EVLSRQEMVSQLQRELQSEEQNTHPRERVQLLSKR----------QMLQEAIQGLQIALCSQD----------KLQAQQELLQSKME------------------QLGTGEPPAVPLLQDDRHSTSSTEQERE----GGRTPTLEILKSHFSGIFR--PKFSIPPPLQL--------------------------------------------------------------------------------------VPEVQK-----------------------------------------------------------------------------------------------------------------------------------------PLYEQLWYHGAIPRAEVAELLTHSGDFLVRESQGKQE--YVLSVMWDGQPRHFIIQSS-DNLYRLEGDGFPSIPLLITHLLSSQQPLTKKSGVVLFRAVPKDKWVLKHEDLVLGEQIGRGNFGEVFSGRLRADNTPVAVKSCRETLPPDLKAKFLQEARILKQYNHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADGIYAASAGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPN---LTNQQTREFVEKGHRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSIICQELHSIRKRHR---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07332-1", "uniprot_id": "FES_HUMAN", "id": "P07332-1", "name": "Tyrosine-protein kinase Fes/Fps", "aln": "MGFSSELCSPQGHGVLQQMQEAELRLLEGMRKWMAQRVKSDREYAGLLHHMS--LQDSGGQSRAISPD--SPISQSWAEITSQTEGLSRLLRQHAEDLNSGPLSKLSLLIRERQQLRKTYSEQWQQLQQELTKTHSQDIEKLKSQYRALARDSAQAKRKYQE------ASKDKDRDKAKDKYVRSLWKLFAHHNRYVLGVRAAQLHHQHHHQLLLPGLLRSLQDLHEEMACILKEILQEYLEISSLVQDEVVAIHREMAAAAARIQPEAEYQGFLRQYGSAPDVPPCVTFDESLLEEGE-PLEPGELQLNELTVESVQHTLTSVT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DELAVATE------------------------MVFRRQEMVTQLQQELRNEEENTHPRERVQLLGKR----------QVLQEALQGLQVALCSQA----------KLQAQQELLQTKLE------------------HLGPGEPPPVLLLQDDRHSTSSSEQERE----GGRTPTLEILKSHISGIFR--PKFSLPPPLQL--------------------------------------------------------------------------------------IPEVQK-----------------------------------------------------------------------------------------------------------------------------------------PLHEQLWYHGAIPRAEVAELLVHSGDFLVRESQGKQE--YVLSVLWDGLPRHFIIQSL-DNLYRLEGEGFPSIPLLIDHLLSTQQPLTKKSGVVLHRAVPKDKWVLNHEDLVLGEQIGRGNFGEVFSGRLRADNTLVAVKSCRETLPPDLKAKFLQEARILKQYSHPNIVRLIGVCTQKQPIYIVMELVQGGDFLTFLRTEGARLRVKTLLQMVGDAAAGMEYLESKCCIHRDLAARNCLVTEKNVLKISDFGMSREEADGVYAASGGLRQVPVKWTAPEALNYGRYSSESDVWSFGILLWETFSLGASPYPN---LSNQQTREFVEKGGRLPCPELCPDAVFRLMEQCWAYEPGQRPSFSTIYQELQSIRKRHR---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q7T0-1", "uniprot_id": "A0A2R8Q7T0_DANRE", "id": "A0A2R8Q7T0-1", "name": "Tyrosine-protein kinase", "aln": "MGFAEDLWCPQGHAALMKLQDSELRLMEVMKKWMMQRAKSDREFSMQLHQMSAMVEKMEGTQPGGGLNYISQFNKSWNVLVSQTESLSRIMRKHSDDLMVGPLSKLTLLIRDKQQLRKTYGEQWTLLNQDMCRVTQTELDRLKSSYRQLVRDATYAKKKYQE------ASKDRERDKAKERFIKATLKLHEHHNEYVLSVKAAQVHHQLHYGQSQPALLGALQTLQEEMVLILKEILQEYFDLSSLIQDEVVSVHTEMANALKAIQPHKEYDNFIQQNRYIREVPACVEFDCSLLEEAD-ALEPEDLQLNELTVEGIQHRLTAVE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EELLGLAS------------------------TLSSQQATVNQLELDLQDEERSANIGQRVYQFSKR----------NALEDSRQQVVLSMVVRA----------RLEAQRRLLADKLQ------------------CLGTNELPSLG-LDDDRISLTSSNSERDK---DHKHLNIDVIRNHLSSLFK--PKYTVPPALTP--------------------------------------------------------------------------------------VPDVEK-----------------------------------------------------------------------------------------------------------------------------------------PLTQQVWYHGAIPRMEVQELLKNDGDFLVRESQGKQE--YVLSVHWGGQCRHFLIQST-DGVYRLDGEGFISVPLLVNHLFNSHQTVTKRTEIVLKKPIPKDKWVLEHDDVILGQSIGRGNFGEVFSGRLRSDNTPVAVKACRENLPAEHKNKFLMEARILKQYDHPNIVKLIGVCTQKQPIYIIMELVQGGDFLTFLRTEGHNLKSSMLIRMAENVASGLAYLESKKCIHRDVAARNCLVGEESVVKISDFGMSREEQDGVYSATGGMKQIPVKWTAPEALNYGRYTTESDVWSFGVLLWETFSRGVTPYTIPTVMSNQQTRDEVERGYRMPAPNNCPDEIYTLMCQCWQYDPRKRPSFLKLKADLGALCQ------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18106-4", "uniprot_id": "FER_DROME", "id": "P18106-4", "name": "Tyrosine-protein kinase Fer", "aln": "MGFSSALQSRAAHEALIVRQDAELRLMETMKRSIQMKAKCDKEYAISLTAVA---QQGLKIDRADEMQG-SLISKSWRSYMDELDHQAKQFKFNAEQLEV-VCDKLTHLSQDKRKARKAYQEEHAKIAARLNHLT-DEVVRKKSEYQKHLEGYKALRTRFEENYIKAPSRSGRKLDDVRDKYQKACRKLHLTHNEYVLSITEAIEVEKDFRNVLLPGLLEHQQSVQESFILLWRNILQEAAQYGDLTADKYKEIQKRIDTVIGSINPTEEYGEFTEKYKTSPTTPLLFQFDETLIQDIPGKLQSSTLTVDNLTVDWLRNRLQELEGAVRDCQEKQMKMIEHVNGGSPVANGSIISNGSNTSNGIQSNKDSLCRQSKDLNALRCQEKQKQKLVDMIKCALNEVGCEELPSGCDDDLTLEQNFIENGYNNEQQRSNSTSSPGLGIMNELMRRGGVLTLLRGRGRHFKRKSTPQPATPMTRSRQGRFNKLQPRSQSLGSLSVIRDGNGPSPARYEPITNHRLRQAASVHYLGEEIATSSTNPPDLTRLRRTQCSMLCLGEDEEPVVLASPAPLTQLTAAVLTNTNNNHIYADLELDKKKDTSPSPECKGEQIQPKKEQIRIEINQTAPQNSIDAHLDRIDELNRVLDDRLKRTLQPSDDVNAIESAEENHIQTRKLAKDPDSQTKRSSSSSSECRSSKDTSHSKKRSLSFSQKSISNIFSNLKEFSKSPLVRMGKNHILNEEQDAKRTQPSQHHHSSGSDCPTNSSSSSSNNNNNNKNTSSNSNHSASQSTIITSTITTTITTTTTTTPSKENSRLKFKVPKIQKKSKAIRNTFRSKLLNFQLKRSKPCKQCTKRRRIHPSKSVFDFAKEFEVEQPAGSAADEQFCNCPPAGQKPVKPSVQISGHKDHPFESSSGELDENSDRDIDNDEEEEDSASDDVLSMKDHCYCVPSLAASISLSTNRPLYEEEWFHGVLPREEVVRLLNNDGDFLVRETIRNEESQIVLSVCWNG-HKHFIVQTTGEGNFRFEGPPFASIQELIMHQYHSELPVTVKSGAILRRPVCRERWELSNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMGMCRDAAAGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFGMSREEEE--YIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSG---MTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEIYNVVDALILRLDNSH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:. * . .* .: *::****:* *:: : :.*.*:*:: * :: :. . . : * ..:** .: : :: :: ::::* .**: * ::::: **:* *: : : : :: : *:.*: .. : :::* : ..:. *..:::: :: **. **.***.: * .: . *.** * ::*.: : ::**** : ..* *. :: .: . *:* ** * .: .* . ** :*::: *:. * :::**:: ::: * : :*: : : :.** : : .. : : *: : :: : : : : ::: ..:* ::: : . : . : .* * :*:: . . : .:.. :. :*.:* ::: .* : :*.::* ** :: *:**.:** ** .** :.*******: ::* **** *.* :**::*: :. :*::* * *: *: * :. .:* :: :* :.: :::* *.::*::* : *******:*:..:*:: : ****:** .** : * *** *.******.*****:***:*.***** *:**** **.:**:**.:. * : * :.*:*: ***** *****:******* : :*********** : * .: *::*:***********:*:*:: .****:*:*:** ** * :**. ::*.::*: :: * *:* *: *: :: ** *** :. .** * : : :: ", "identical_positions": 246, "similar_positions": 288, "identity": "18.4%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100812-11", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E7EZL0-1", "uniprot_id": "E7EZL0_DANRE", "id": "E7EZL0-1", "name": "Serine/threonine-protein kinase LMTK2", "aln": "--MEALLGGGVCFLGFVTLTH----AAPVSNTLSAEAAGYVDVSLSIPLLLSLAVTLALVVLLLNCASCCKEQEINFKEFEDHFEDEVDFTPPAEDTPSMQSPAEVYTLAVPPVHLPGPPHLQLPRITDVSSGPHVARHSLSYIQEIGNGWFGKVLLSEIYVDPGVARAVVRELKANASSKEQNEFLQQGDPYRVLQHPNILQCLGQCVEAIPFLLVFEYCELGDLKSYV-SQHEWLYRNGELLQLQKMACEIAAGVTHMHKHNFLHSDLALRNCFLTTDLTVKVGDYGIGPTNFKEDYITTEDDQCVALRWLSPELIGELHGGLITSEQTKPSNVWALGVTIWELFECAKQPYHHLSDREVLHHVLKDQQVRLLKPQLDLPYSERWYEVLQFCWLPADKRATAEEVHRLLTYLRMQGQKDVEDDFEQRWSSLKPNPSTRQATVSHSSFPILEQFDD---GREPDEVLTVTETSRGLSFEYVWEAAKHDHYDSHNRSAMDTTLNYHSMFFPVPRQDIQAHFPDTTAQAADGG----RVPETLPVFDAHKASSGNDYFIKLEELDESEIGMGDSQGAEGTNTS-------EQNQYVVLQDVRLDESSTDADFFHQSIDSKDSFLQDSHIWSSSEHDSPYHTNIFSEGD-AKMEDSHSFEGGFMELP---EMMNLPKRDSDEANGKEASFQTSFLGVGPEAIH----LEISD-QGSSDVMKLLNTEKLSDNFMFLKDNSLMKDKSEVSPPDSINIKRSIIETNVSDSVNLTGESLKSAGSSAQLKDEFLDLVSPILDDFLSPLKGREAMVPFDILVTGSNRLPDTNG----------SLRSPKSRNYSSSESTSESVEVIVDSPS-DSHQSLESATTDTLQMCIDAKPPSLEECFVASKDNGQHIGISDAAELSFTTSPVGEYTELG-----LTEGLTSSDSMSDIMETAKDIPPSEAIDQDTLLDNHATQDMSSLLVLDSCLDQISQDSLLDDSTSSTLPTIENSAETPDSLDSLDVAHGQSLDISVN---KLQPPYKAADSGYETENLESPEWNSQTGLKDEDNDAAVEPSALVPPEIVVSEVDSVPDVQVNAGGVDHQQEPGEFPLGGNYRDSAYFSDNE-ELDKKSDDVSGNG-SSIWLQNNQETNESRVAR---ALEEHSRSETSSQ-----------SAGPTVESTITATKTLVPELVLTTEEDWSK-----EKPLTVDD---SNQNHPCDVPETPTTSLPPPTEVMLHAKLTRTYAGEGTKKKEPDMEGRYLGKLDGS---YGTEDGMDADEEDENSDDSDEDMRAYRLHSSSSECSEDEVVHPVPIIISDNSSSLNLKSLLKPKTLQTAKATSEEGRDGDSRRGVSFFDDVTVYLFDQETPTKELSEHTLDPSSQLSDFSSPVASSSYLNRFTNSESSTDEEGGAFEWDDDFPSPEPNFLSKAASDHSSSRSSGTSAASKYFSPPPANRSLDQSWTSPSSYSRFSISPASIASFSLTHLTDSDMEQGGSGEDGEKD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IWU2-1", "uniprot_id": "LMTK2_HUMAN", "id": "Q8IWU2-1", "name": "Serine/threonine-protein kinase LMTK2", "aln": "MPGPPALRRRLLLLLLVLLIAGSAGAAPLPQTGAGEAPPAAEVSSSF-VILCVCSLIILIVLIANCVSCCKDPEIDFKEFEDNFDDEIDFTPPAEDTPSVQSPAEVFTLSVPNISLPAPSQFQPS-VEGLKS--QVARHSLNYIQEIGNGWFGKVLLGEIYTGTSVARVIVKELKASANPKEQDTFLKNGEPYYILQHPNILQCVGQCVEAIPYLLVFEFCDLGDLKAYLRSEQEHMRGDSQTMLLQRMACEVAAGLAAMHKLHFLHSDLALRNCFLTSDLNVKVGDYGIGFSRYKEDYIETDDKKVFPLRWTAPELVTSFQDRLLTADQTKYSNIWSLGVTLWELFDNAAQPYSNLSNLDVLNQVIRERDTKLPKPQLEQPYSDRWYEVLQFCWLSPEKRPAAEDVHRLLTYLRLQSQRDSEVDFEQQWNALKPNTNSRDSSN-NAAFPILDHFARDRLGREMEEVLTVTETSQGLSFEYVWEAAKHDHFDERSRGHLDEGLSYTSIFYPVEVFESSLSDPGPGKQDDSGQDVPLRVPGVVPVFDAHNLSVGSDYYIQLEEKSGSNLELDYPPALLTTDMDNPERTGPELSQLTALRSVELEESSTDEDFFQSSTDPKDSSLPG-DLHVTSGPESPFN-NIFNDVDKSEDLPSHQKIFDLMELNGVQADFKPATLSSSLDNPKESVITGHFEKEKPRKIFDSEPLCLSDNLMHQDNFDPLNVQELSENFLFLQEKNLLKG--SLSSKEHINDLQTELKNAGFTEAMLETSCRNSLDTELQFAENKPGLS-LLQENVSTKGDDTDVMLTGDTLSTSLQSSPEVQVPPTSFETEETPRRVPPDSLPTQGETQPTCLDVIVPEDCLHQDISPDAVTVPVEILSTDARTHSLDNRSQDSPGESEETLRLTESDSVLADDILASRVSVGSSLPELGQELHNKPFSEDHHSHRRLEKNLEAVETLNQLNSKDAAKEAGLVSALSS-DSTSQDSLLEDSLSAPFPASEPSLETPDSLESVDVHEALLDSLGSHTPQKLVPPDKPADSGYETENLESPEWTLHPAPEGTADSEPATTGDGGHSGLPPNPVIVISDAGDGHRGTEVTPETFTAGSQGSYRDSAYFSDNDSEPEKRSEEVPGTSPSALVLVQEQPLPEPVLPEQSPAAQDSCLEARKSQPDESCLSALHNSSDLELRATPEPAQTGVPQQVHPTEDEASSPWSVLNAELSSGDDFETQDDRPCTLASTGTNTNELLAYTNSALDKSLSSHSEGPKLKEPDIEGKYLGKLGVSGMLDLSEDGMDADEEDENSDDSDEDLRAFNLHSLSSE-SEDETEHPVPIILS-NEDGRHLRSLLKPTAANAPDPLPEDWKK--EKKAVTFFDDVTVYLFDQETPTKELGPCGGEACGPDLSGPAPASGSPYLSRCINSESSTDEEGGGFEWDDDFS-PDP-FMSKTTSNLLSSKPS--LQTSKYFSPPPPARSTEQSWPHSAPYSRFSISPANIASFSLTHLTDSDIEQGGSSEDGEKD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6S5J6-1", "uniprot_id": "KRIT1_MOUSE", "id": "Q6S5J6-1", "name": "Krev interaction trapped protein 1", "aln": "-------------------------------------------------------------------------MGNPENIEDAYVAVIRPKNTASLN-SREYRAKSYEILLHEVPIEGQKKKRKK---------VLLETKLQSNSEIAQGILDYVVETTKPISP--ANQGIKGKRVVLMRKFPLDGEKTGREAALFIVPSVVKDNTKYAYTPGCPIFYCLQDIMRVCSESSTHFATLT--------ARMLIALDKWLDERHAQSHFIPALFRPSPLERIKTNVINPAYAAELG---------QVDNSLHMGYSALEIK------------SKMLALEKADTCIYNPLFGSDLQYTNRVDKVVINPYFGLGAPDYS--KIQIPKQEKWQRSMS---------SVVEDKERQWVDDFPLHRNACEGDSELLSHLLDKGLSVNQLDNDHWAPIHYACWYG-----KVEATRILLEKGK--------------CNPNLLNGQLSSPLHFAAGGGHAEIVQILLTHPDIDRHITDQQ-----GRSPLNVCEENKQNNWEEAAKLLKDAIN--------------------------KPYEKVRIYRMDGSYRSVELKHGNNTTAQQIMEG--MRLSQETQRYFTIWICSENLSLQFKPYHKPLQQVHDWP------EILAELTNLDPQRETPQLFLRRDVG---------LPLEVEKKIEDPLAILILFDEARYNLLKGFYTAPDAKLITLASLLLQIVYGNYESKKHKQGFLNEETLKSIVPITKLKSKAPHWINRILHEYKN------------------------------------------LSLSEGVSKEMHHLQRMFLQNCWEIPTYGAAFFTGQIFTKASPSNHKVIPVYVGVNIKGLHLLNMETKALLISLKYCCFTWQLG--------------------------------DAGTCFQIHSMENKMSFIVHTKQAGLVVK--LLMKLNGQLMPSERNS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::** : : . .*. . * : *: : : : : : . : : : . .*. .**.:* :. *: .. *. :: :. * : * :: *.::: : . : :.: :: : : :. : :* : : * .: . * . : . .* *. : .: . : : : *: :* : .. ::: : : * : : *:: : ::: * .::* . :. ...*: .* . :. * * * *. . . .: : : : : : . : *..: . .. :. * : : . : *. : . : * : :: . .: *:: . :: .:: * . :: : . . :. : . : :. : : * .: : *. . : : :. :*: * :. .* : * . : :: . . . :: :. . * . :* . :: .: : .: . .. :: :. . . . : . .. .: :. . :: . .:* : . :: : . .:: . . : ** . . :*: . * ", "identical_positions": 50, "similar_positions": 242, "identity": "3.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100812-13", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XJV6-1", "uniprot_id": "LMTK3_MOUSE", "id": "Q5XJV6-1", "name": "Serine/threonine-protein kinase LMTK3", "aln": "MPAPGALILLAAVS----ASGCLASPAHPDGFALSRAPLAPPYAVVLISCSGLLAFIFLLLTCLCCKRGDVRFKEFENPEGEDCSGEYTPPAEETSSSQ-SLPDVYILPLAEVSLPMPAPQPPHSDISTPLGLSRQHLSYLQEIGSGWFGKVILGEVFSDYSPAQVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGVCVETLPFLLIMEFCQLGDLKRYLRAQRPPEGMSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYYLTPERLWVPLRWAAPELLGELHGSFVLVDQSRESNVWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQSCWRPPAQRPSASDLQLQLTYLLSERPPRPPPP------------PPPPRDGPFPWPWPPSHSAPRPGTLS-----------------------SQFPLLDGFPGADP----DDVLTVTESSRGLNLECLWEKARRGAGRGGGAPPWQPASAPPAPHTNPSNPFYEALSTPSVLPVISARSPSVSSEYYIRLEEHGS------------------------------------------------------------------------------------------------------PPEP----------------------------------------------------LFPNDWDPLDPGVPGPQAPQTPSEVPQLVSETWASPLFPAPRPFP---------------------------------------------------------------------------------------------------------------------------------------------AQSSGSGGFLLSGWDPEGRGAGETLAGDP-------------AEVLGEQGTAPWAEEEEEE----------------------SSPGEDSSSLGGGPSRRGPLPCPLCSREGPCS-CLPLERGDAVAGWGDHPALGCP--------------------------HPPEDDSSLRAERGSLADLPLVPPTSAPLEFLDPLMGAAAPQYPGRGPPPAP---------PPPPPPPRASAEPAASPDPPSALASPGSGLSSPGPKPG--------------------------------------DSGYETETPFSPEGAFPGGGAAKEEGVPRPRAPPE------------------------------------------------------------------------PPDPGAPRPPPDPGPLPLPGSQEKPTFVVQVST---------------------EQLLMSLREDVTKNLLGDKGSTPGETGPRKAGRSPAN---------------------------------------------------------------------REKGPGPNRDLTSLVSRKKVPSRSLPVNGVTVLENGKPGVP---------DMKEKVAENG----------------------------------------------------------------LESPEKEERALVNGEPMSPEAGEKVLANG----------------------------------------------------------------------------VLMSPKSEEKVAEN-------GVLRLPRNTERPP-------------------------EIGPRRVPGPWEKTPETGG-------LAPETLLDRAPAPCEAALPQNGLEMAP--------------------------------------GQLGPAPKSGNPDPGTEWRVHES------------------------------------GGAPRAPGAGKLDLGSGGRALGGVGTAPAGGPASAVDAKAGWVDNSRPLPPPP---QPLGAQQRRPEP---------VPLKARPEVAQEEEPGVPD-----------------NRLGGDMAPSVDEDPLKPER----------------------------------------------KGPEMPRLFLDLGPPQGNSEQIKAKLS-----------------------------------------------RLSLALPPLTLTPFPGPG-------------------------------------------------PRRPPWEGADAGAAGGEAGGAGAPGPAEEDGEDEDEDE----------------------------EDEE-------AAGSRDPGRTREAPVPVVVSSADGD-------------------------------------------TVRPLRGLLKSPRAADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQGTPEGDTEPSTPPAPPTPPHPTTPGDG------------------------------------------------------FPNSDSGFGGSFEWAEDFPLLPPPGPP---------------LCFSRFSVSPALETPGPPARAPDARPAGPVEN------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96Q04-1", "uniprot_id": "LMTK3_HUMAN", "id": "Q96Q04-1", "name": "Serine/threonine-protein kinase LMTK3", "aln": "MPAPGALILLAAVS----ASGCLASPAHPDGFALGRAPLAPPYAVVLISCSGLLAFIFLLLTCLCCKRGDVGFKEFENPEGEDCSGEYTPPAEETSSSQ-SLPDVYILPLAEVSLPMPAPQPSHSDMTTPLGLSRQHLSYLQEIGSGWFGKVILGEIFSDYTPAQVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGLCVETLPFLLIMEFCQLGDLKRYLRAQRPPEGLSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYYLTPERLWIPLRWAAPELLGELHGTFMVVDQSRESNIWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQSCWRPPAQRPSASDLQLQLTYLLSERPPRPPPP------------PPPPRDGPFPWPWPPAHSAPRPGTLS-----------------------SPFPLLDGFPGADP----DDVLTVTESSRGLNLECLWEKARRGAGRGGGAPAWQPASAPPAPHANPSNPFYEALSTPSVLPVISARSPSVSSEYYIRLEEHGS------------------------------------------------------------------------------------------------------PPEP----------------------------------------------------LFPNDWDPLDPGVPAPQAPQAPSEVPQLVSETWASPLFPAPRPFP---------------------------------------------------------------------------------------------------------------------------------------------AQSSASGSFLLSGWDPEGRGAGETLAGDP-------------AEVLGERGTAPWVEEEEEEEEG-------------------SSPGEDSSSLGGGPSRRGPLPCPLCSREGACS-CLPLERGDAVAGWGGHPALGCP--------------------------HPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAP---------PPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPG--------------------------------------DSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPE------------------------------------------------------------------------PPDPGAPRPPPDPGPLPLPGPREKPTFVVQVST---------------------EQLLMSLREDVTRNLLGEKGATARETGPRKAGRGPGN---------------------------------------------------------------------REKVPGLNRDPTVLGNGKQAPSLSLPVNGVTVLENGDQRAP---------GIEEKAAENGALGSPEREEKVLE------------------------------------------------NGELTPPRREEKALENGELRSPEAGEKVLVNG----------------------------------------------------------------------------GLTPPKSEDKVSEN-------GGLRFPRNTERPP-------------------------ETGPWRAPGPWEKTPESWGPAPTIGEPAPETSLERAPAPSAVVSSRNGGETAP--------------------------------------GPLGPAPKNGTLEPGTERRAPET------------------------------------GGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEP---------APPRARPEVAPEGEPGAPD-----------------SRAGGDTALSGDGDPPKPER----------------------------------------------KGPEMPRLFLDLGPPQGNSEQIKARLS-----------------------------------------------RLSLALPPLTLTPFPGPG-------------------------------------------------PRRPPWEGADAGAAGGEAGGAGAPGPAEEDGEDEDEDE----------------------------EEDEEAAAPGAAAGPRGPGRARAAPVPVVVSSADAD-------------------------------------------AARPLRGLLKSPRGADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAPPEGDTDPSTPPAPPTPPHPATPGDG------------------------------------------------------FPSNDSGFGGSFEWAEDFPLLPPPGPP---------------LCFSRFSVSPALETPGPPARAPDARPAGPVEN------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6F1-1", "uniprot_id": "A0ACD6B6F1_DANRE", "id": "A0ACD6B6F1-1", "name": "non-specific serine/threonine protein kinase", "aln": "MSQQCWVIVLVGLMSYFNPERALGAPQKEVSLSRDDSLSPPPYVIILISCSGLVSFVLLLLTCLCCKRGSVGFNEFDNAEGEECSGASSPVPEDSLSSCPSLPEVYTLPLRDKNCHSIP-----NGTDSSQCFRRHTLNYLQEIGNGWFGKVILAEVLCDCSSYQAVVKELRVSASPLEQRKFLAESEPYRSLQHPNILQCLGQCSESVPFLLVMEFCQLGDLKRYLRAQRKSDGMTPDLLNRDLLTLQRMAYEITSGLLHLHENNYIHSDLALRNCLLTSDLTVRIGDYGLSHNQYKEDYYLTPDKLWIPLRWIAPELLEEFRGNLIVTDQTKTSNVWSLGVVIWELFEFGAQPHRHLSDEEVLTFVIRERQITLAQPRLKLAHADYWYEVMQSCWLPTSQRPTVSEVFLLLSSLLAAEQGSRKSTRRDEDEEDYDEDSGQRRRGESDESFERRWDALRPPAFQSAAHKLLRERVYGREDGCLRGNGNSFPLLDPVDNITPTSELDDILTVTETSKGLNFEYFWEKAHGRRG--------YKPLPPPQPIPTPSSGHRQTLDTPTVVPVISARSPSLASEYYIRLEEHTPQDKSPSLGKGRSLRTNAKCPGDLELVELQTGIAAKDRSAFCHQDGFRRGSSQTVRSSEVKVLVPNTGLVEFSKESCNRVTDYAVIDIGEPNQKSLGSQAPLLPPKPRSMSMSSGSHLHSRPLPAPPLGYARTYGLDIYPGSSYPSGKVETSDSLLMSSLSKANFDHLGLNRTHQTLPPSPSLSPSIPPSSGSHSMFLPPQTCPPPLPPHYRLQKGQNYSSEIYSRYNTMHLQRDPLSCEFNDARNADRGMTRSQSLYNSRDAPTSHITDDEFSSRMTRSQSTIPKIERTSSSSPEFSKDDDNNDYEDDDDPFMSPHRPMSSTTIQHTSLADDPATTELFSRGMKRTQSRLATILPAIWREDAVMQRERVAAARKSPIHLFLTEISNDPVDMKDGENSWTRESEGRKDKGMRRSQSLISELDSTSQAWASDKDFLSGYEGNTKKRDLFLTEIETSVSDCEDAYDGEGGTPVSRFGTTPHLFAFPSDLPAYSEAEDAFLSGMKKSHSLLSEISDESIEPEAKKGEMTREEFLKEIQSAETFLTEIITRQRKKEESVSPTPLSPEYESICIDPESSQTIQFESERTRAGNPPGDTKEAIYAQVTKRAKRSEIKVAIRPEIPVLQIASELQNLESVQKLTKVSQFTCEIEPEKNSHNDFPPAEVMPKNGPHLEQITSVIKEKQDSLQCQNKHDSIREGAIETIEAIKVNGSQSWDENQISCDMHIRSVENDLKDMFVQSKERLQKNDHSALPGIKVMTSNATLRNSEEPSEIPKQTPNESTSLNISPKTNLPGGTSSTMTREYSSDISQHSPTANRLSDSFEQTTLTDKEIYSRTTWDNKDTKGANENILPSDSLFSLNDSSTDVFHSPMVHEPNSDQSLSTMTPSDSVLSPLTSSSLDCLTPGDSWLGGGSSGWRALGTETPHRDSAYFSDSDLDGGEGLSRRGTDVLGSSRPGSARTGERGLLMGIEEKIEDEGLLEHFEKEVEMKQDIQELWISNNSADVKKGLIHLTSTDIPGDSQSDCNAEIIAKLFFNGEDEPNKGAPFNNSLNFQNSTLIKKSELEKMLHESGAMDLRLLAHVVSEPQNHISEQECEEELIEHCSYVQKAKYEETRCTTPEFSIDEQSSDTSKSRLSRFYSLQSDYSKCISSPEMNTKLSNNDTECGMSQVIWSETNAEQPTGVKRTELDIQDTDANELGLRNLSYSEEGEDEQAKERSESQLAVGELCFTIKESSQSTADANASSLEQSKEEHSNEFGRGASMGLELKEKELWSALDEDYGMEETVRSEFNCQAFQQGELHLWPVENDQWAAAETRTPEAGLSSELFPSFGKKTWVADEHLVVSHEFWESEANDELADSESHPSAQRVCEDTFNDEKVGQAVYPSPERLIFSDGTKGAFSSLQTPLEKPNVQQEENMENPDLESGAQEHDTCNTKMEVENLEIPEQEPPVQHRPVEMLIDTHNSETCLQNYLGGEMFREDDKKEFDSHENMVGVGGCVTQSPSFSITNPTDESLKNHKESLSGHNKNVLTDQTKAKCAPMTEASKMLGAAHEDHQTCTINMSNSITDLADSSHFISVHTDCHSAETSRHDLDNNHCPTTISDAFLEKERSDSPSCPSLTISTDPEPCNIHSSNVQCSAPALIPMELSECTASTLAEVEKCPGSSSFPNTVHHIEIKTSSSLFCSADEMPDKGHVDPSGCLDDVELAISTTTHSKGITANLGQKLHTSLMKENHIQSESNSLHEDDRNSLSQKAAHPPLSQCSLNSIPELLISEWKDLDEEPLEDFEKLEQLCCISGDEETLGDLFLGNLDLLESLKRNPEQRTSSASGIINQDDSANSEEKTRVELKEEVDGISESTTAVLQHLEQYGNISSNFPGEAQQSMEKGTGQPLSPCHSSDGSKGQRSLSKMPTKNGLMMQVCEERLQYSLSENVKTNVLWGSTISDSVIIHPWGASTTSSSEENAASKDFLDNESNKEDTPPSSPSVLLSELAEAQTEELTVLEQPEVTPSLPAANQAMKAKLARLSLSLPPLALSLPLSPNTKGGFWEGSEYRGGRRRAASTGSDPDEDEEEEQEEESPRRVIVVTETDVDKRVGLRSLLKSPKEPVDKENRDRGRNVSFFDDVTVYLFDQETPTNELSSGSTSTSPHGKHPSTDGLGTGSHKASKSKEHVVKARSPTGVTSSSSSRFTVSPADDPHLV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :*:*..: .. .*.:* : .:: . : .***.::*******::*::***********.* *:**:*.***:*** :* .*:: ** ***:** *** : . . .. :. : *: *.******.********.*::.* :. *.******.**.*******::*::*********:***** * *::****:***************** .:*::*:* *** *****. **: ** ***.:**:************************:*.:*********::**:**** ***** *::*.:::.**:: **:*****.:**********:*********:**:*::::.**:*****.:*****:::**** *.:***:.*:: * *: **: . .. . * * .: .* ** ::. . ***** . . * **:*****:*:***:* :****: * . .** * ..**. . ::*.**:*:*********::********** . **:* * ::* *. . . * :** *.: ..: : .:* .*:. * .* . :* : * :. * :*. * : * .*..*.* . :* : *. *...:*. : : : . *. . * * .*: :* * * . . .::. . .*::*.:: : .:. ** :: : . .*.* . * .. . : :: : : :**. .. . : .* . :. ::.. *.* .:* .*. *: .. : : .. .: * . :*. :* ..*..:: :. .* . * :.. :. * :* . * .* :.. : :** : : . . . .*. .*. ** .. . .::** ::* .* .:. : *. . . **:* :. : .*: : *:::* : *:*:*. * * . . .:: : * :.:: : .:. .:. * . * * * .. ..:* *. *: ..: *.* :: .: . * .. *. *.. * ... :. * : *. . ... * ** . . . **: . * . .... * . *.. **..: : : . .:* * : *.**::. * * . . : .** . *... :*. . .* . ..: *::. * . . . * :: . * * . . *:::. .*:. *.:.:* *.:: .: ..*. * . * * * :: . . * :* *.: ..* ...:.. . .* *. .**..* :.: .*:*:* :.. . :* ** : .: ", "identical_positions": 450, "similar_positions": 479, "identity": "16.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100812-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYF4-1", "uniprot_id": "ITB6_RAT", "id": "Q6AYF4-1", "name": "Integrin beta-6", "aln": "----------MGIELVCLFLLLLGRNDHVQGG-----CAWSGAETCSDCLLTGPHCAWCSQENFT-------------------------HLSGAGERCDTPENLLAKGCQLPFIENPVSQVEILQNKPLSVGRQKNSS-------------DIVQIAPQSLVLKLRPGGEQTLQVQVRQTEDYPVDLYYLMDLSASMDDDLNTIKELGSRLAKEMSKLTSNFRLGFGSFVEKPVSPFMKTTPEEITNPCSSIPYFCLPTFGFKHILPLTDDAERFNEIVRKQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDNRNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVLGDTEGLNLSFTALCSNGILFPHQKKCSHMKVGDTASFNVSVSITNCEKRSR----KLIIKPVGLGDTLEILVSAECDCDCQREVEAN---SSKCHHGNGSFQCGVCACNPGHMGPRCECGEDMVS------TDSCKESPGHPSCSGRGDCYCGQCVCH--LSPYGSIYGPYCQCDNFSCLRHKGLLCGD--NGDCDCGECVCRDGWTGEYCNCTTSRDACASEDG-VLCSGRGDCVCGKCVCRNPG---ASGPTCERCPTCGDPCNSRRSCIECYLSADGQAQEE--CEDKCKATGATISEE-EFSKDT-SVPCSLQGENECLITFLITADNEGKTIIHNISEKDCPKPPNIPMIMLGVSLAILLIGVVLLCIWKLLVSFHDRKEVAKFEAERSKAKWQTGTNPLYRGSTSTFKNVTYKHREKHKVGLSSDG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z0T9-1", "uniprot_id": "ITB6_MOUSE", "id": "Q9Z0T9-1", "name": "Integrin beta-6", "aln": "----------MGIELVCLFLLLLGRNDHVQGG-----CAWGGAESCSDCLLTGPHCAWCSQENFT-------------------------HLSGAGERCDTPANLLAKGCQLPFIENPVSRIEVLQNKPLSVGRQKNSS-------------DIVQIAPQSLVLKLRPGREQTLQVQVRQTEDYPVDLYYLMDLSASMDDDLNTIKELGSRLAKEMSKLTSNFRLGFGSFVEKPVSPFMKTTPEEITNPCSSIPYFCLPTFGFKHILPLTDDAERFNEIVRKQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDHRNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVLGDTEGLNLSFTALCNNGVLFPHQKKCSHMKVGDTASFNVTVSVSNCEKRSR----NLIIKPVGLGDTLEILVSAECDCDCQREIETN---SSKCHNGNGSFQCGVCTCNPGHMGPHCECGEDMVS------TDSCKESPGHPSCSGRGDCYCGQCICH--LSPYGSIYGPYCQCDNFSCLRHKGLLCGD--NGDCDCGECVCRDGWTGEYCNCTTNRDSCTSEDG-VLCSGRGDCVCGKCVCRNPG---ASGPTCERCPTCGDPCNSKRSCIECYLSADGQAQEE--CADKCKAIGATISEE-DFSKDT-SVSCSLQGENECLITFLITTDNEGKTIIHNINEKDCPKPPNIPMIMLGVSLAILLIGVVLLCIWKLLVSFHDRKEVAKFEAERSKAKWQTGTNPLYRGSTSTFKNVTYKHREKHKAGLSSDG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18564-1", "uniprot_id": "ITB6_HUMAN", "id": "P18564-1", "name": "Integrin beta-6", "aln": "----------MGIELLCLFFLFLGRNDHVQGG-----CALGGAETCEDCLLIGPQCAWCAQENFT-------------------------HPSGVGERCDTPANLLAKGCQLNFIENPVSQVEILKNKPLSVGRQKNSS-------------DIVQIAPQSLILKLRPGGAQTLQVHVRQTEDYPVDLYYLMDLSASMDDDLNTIKELGSRLSKEMSKLTSNFRLGFGSFVEKPVSPFVKTTPEEIANPCSSIPYFCLPTFGFKHILPLTNDAERFNEIVKNQKISANIDTPEGGFDAIMQAAVCKEKIGWRNDSLHLLVFVSDADSHFGMDSKLAGIVIPNDGLCHLDSKNEYSMSTVLEYPTIGQLIDKLVQNNVLLIFAVTQEQVHLYENYAKLIPGATVGLLQKDSGNILQLIISAYEELRSEVELEVLGDTEGLNLSFTAICNNGTLFQHQKKCSHMKVGDTASFSVTVNIPHCERRSR----HIIIKPVGLGDALELLVSPECNCDCQKEVEVN---SSKCHHGNGSFQCGVCACHPGHMGPRCECGEDMLS------TDSCKEAPDHPSCSGRGDCYCGQCICH--LSPYGNIYGPYCQCDNFSCVRHKGLLCGG--NGDCDCGECVCRSGWTGEYCNCTTSTDSCVSEDG-VLCSGRGDCVCGKCVCTNPG---ASGPTCERCPTCGDPCNSKRSCIECHLSAAGQAREE--CVDKCKLAGATISEEEDFSKDG-SVSCSLQGENECLITFLITTDNEGKTIIHSINEKDCPKPPNIPMIMLGVSLAILLIGVVLLCIWKLLVSFHDRKEVAKFEAERSKAKWQTGTNPLYRGSTSTFKNVTYKHREKQKVDLSTDC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QGX0-1", "uniprot_id": "F1QGX0_DANRE", "id": "F1QGX0-1", "name": "Integrin beta", "aln": "----------MGIVSLCLVLYFW--LDSVGGT-----CSQISALSCDDCLQLGPQCAWCTLQNFT-------------------------DFFPVDERCDTPEALLQKGCSGEFVEFPVTNVKVLKDQ--GLGKNSGHT-------------NVSYIAPQKMRLQLRPGSQLTFQIQVQQPKDHPVDIYYLMDLSASMFDDLKKIKDLGSTLSKEMANLTSKFRLGFGSFVEKPVLPFIKITREELANPCRSFDLECLPTFGYRHLLSLTSSTDRFNEIISKQQISANIDIPEGGFDAIMQAAVCGDRIGWRNDSMKLLVFVSDADSHFGMDSKMSGIVVPNDGECHLDGNNEYSMTAHLEYPTLGQLVDKLVENNILLIFAVTKDQKENYENYASLIPGATVGVLASDSRNILELIMTSYKELRSEIDLEVLGNTEGLQMSFTALCQDGTITPGHKNCTNVKAGDVVSFNVTVEIKGCLGGPR----RFSLRPVGFQDALEIELESQCVCSCHQTPETN---SSFCSRGRGALECGECVCDPGFVGPKCECTESQDQ------VSDCRANEGAEVCSGQGECFCGQCVCL--PSSFGRVYGPYCECDNFSCLRFRGELCGG--HGECDCGECVCDSGWMGEFCNCSTSNRSCVSSDG-SVCSGRGRCVCGKCECSVPG---ASGKHCERCPTCGDICSIHRSCAECFLKAK-EPSDE--CAVKCSSLHTAVSNSTDFEESR-AAPCTLQSEESCLLSFSLVASDHG-SIIYNPKLYDCSEPPNAPLIALGVCMSVLIIGIALLVIWKFLVSVHDRKEVAKFEAEKAKAKWQSGTNPLFRSSTSTFKNVTYKSTGQQKSDVSLGR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P11584-1", "uniprot_id": "ITBX_DROME", "id": "P11584-1", "name": "Integrin beta-PS", "aln": "MILERNRRCQLALLMIAILAAIAGQTDAQKAAKLTAVSTCASKEKCHTCIQT-EGCAWCMQPDFKGQSRCYQNTSSLCPEEFAYSPITVEQILVNNKLTNQYKAELAAGGGGSAMSGSSSSSYSSSSSSSSFYSQSSSGSSSASGYEEYSAGEIVQIQPQSMRLALRVNEKHNIKISYSQAEGYPVDLYYLMDLSKSMEDDKAKLSTLGDKLSETMKRITNNFHLGFGSFVDKVLMPYVSTIPKKLEHPCEN----CKAPYGYQNHMPLNNNTESFSNEVKNATVSGNLDAPEGGFDAIMQAIACRSQIGWREQARRLLVFSTDAGFHYAGDGKLGGVIAPNDGECHLSPKGEYTHSTLQDYPSISQINQKVKDNAINIIFAVTASQLSVYEKLVEHIQGSSAAKLDNDSSNVVELVKEEYRKISSSVEMKDN-ATGDVKITYFSSCLSNGPEVQTSKCDNLKEGQQVSFTAQIQLLKCPEDPRDWTQTIHISPVGINEVMQIQLTMLCSCPCENPGSIGYQVQANSCSGHGTSMCGICNCDDSYFGNKCECSATDLTSKFANDTSCRADSTSTTDCSGRGHCVCGACECHKRPNPIEIISGKHCECDNFSCERNRNQLCSGPDHGTCECGRCKCKPGWTGSNCGCQESNDTCMPPGGGEICSGHGTCECGVCKCTVNDQGRFSGRHCEKCPTCSGRCQELKDCVQCQMYKTGELKNGDDCARNCTQFVPVGVEKVEIDETKDEQMCKFFDEDDCKFMFKYSE--QGELHVYAQENKECPAKVFMLGIVMGVIAAIVLVGLAILLLWKLLTTIHDRREFARFEKERMNAKWDTGENPIYKQATSTFKNPMYAGK-----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: :.:. : * . .: . .* *: **** :*. . .: : * * :. . : ... .. :.. :: * **.: * ** . .::: *.:.:***:******* ** ** .:. **. *:: * .:*.:*:*******:* : *::. ::: :** . * ..:*::: :.*...:: *.: : : :*.*:* *********** .* .:****::: :**** :**. *:. *.*:.*:: **** ***. ..**: :: :**::.*: :*: :* : :***** .* **: .. * *::.. * .** *:::*: *.:: *.:::: * .::::: : * .. .:* ::* *: .**.. :.: * .* : : ***: :.::: : * * *.. . . .: . *.*: ** * *. ...* :*** .. . ***:*.* ** * * .. : * :*:****** * :. **.. :* *:**.* * ** *. *.* . :* . .* :***:* * ** * * . ** **:****.. *. :.* :* : : : * :*. .. :. ::.: *.: .*:.* : * .* :: . :*. * :** :::::*:.:* :**:*.:.***:*.*:** *: :***::* **::: :****** * ", "identical_positions": 227, "similar_positions": 267, "identity": "26.24%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100812-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M0C0-1", "uniprot_id": "A0ABK0M0C0_RAT", "id": "A0ABK0M0C0-1", "name": "non-specific serine/threonine protein kinase", "aln": "---MPIALLALAMSSSFFNPSFAFSSHFDPDGAPLSELSWSSSLAVVAVSFSGIFTVIVLMLACLCCKKGGIGFKEFENAEGEEYVADFSEQGSPAATVQNGPDVYVLPLTEVSLPMAKQPGRSVQLLKSTDLGRHSLLYLKEIGHGWFGKVFLGEVHSGVSGTQVVVKELKASASVQEQMQFLEEAQPYRALQHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVTESMAPDPLTLQRMACEVACGVLHLHRHNYVHSDLALRNCLLTADLTVKVGDYGLAHCKYREDYLVTADQLWVPLRWIAPELVDEVHGNLLVVDQTKTSNVWSLGVTIWELFELGAQPYPQHSDRQVLAYAVREQQLKLPKPQLQLTLSDRWYEVMQFCWLQPEQRPTAEEVHLLLSYLCAKGTTELEEEFERRWRSLRPGGSAGLGSASTVPAAAAS---ELTAASSFPLLEQFTS-DGFHVD-SDDVLTVTETSHGLNFEYKWEAGCGAEAYPPPGAAFSPGS-AGRLQELCAP----------------------DSSPPGVVPVLSAHSPSVGSEYFIRLEG-----------------AVPAAGHDPDCAG----CAPSPQ---AVSEQDNNSEESTAASLVMEPLLGHAPPTGGLWGPCDHHSRR--RQEPPCP-SRSPSPGTPMLP-----AEDIDWGVATFCPPFFDD-PLGTSPSGSPGAQPSPS--DEELEEGKTGRAAQCGHWSSN------------MSANNNSGS----------RDPESWDPGYVSSFTDSYRDDCSSLEQTPRAS--PELGHPLSQEDSRDFLPGLVAASPGQESSRCFN-LLPLCPAKGLAPAACLVPPPWTEAAVGGAENPIVEPKLAQEAEGSAEPQLPLPSVPSPSHE------------------GASLPSEEASAP---DIQPASPTPAAGSWVTVPEPAP------------TLDSSSSSLGQEVPSSE-----------------DEDTTEVTSGVFTDLSSDGPHTEKSGIVPALRCLQKQVGTPDSLDSLDIPSSASDGGCEVLSPSAAGPAGGQPRAMDSGYDTENYESPEFVLKEAHES--------SEPEAFGEPASEGESPGPDTLLSVS----LGDLSRKNPYRDSAYFSDLDAESEPNFGPEKHSGIQDSQKEQDLRSPPSPGHESVQAFPR---------------------------PEVS--------SEVLPPPQQSEEPMPE------GPGSEPLEAQGPVEVEPVPGPSHSKCLLLTSAPLSSEGNGT----ESRGPPGPLSGPAQTG----------------------RMGNP----------------------------STSR--SPLCLALPGHPGTSEGRP------EDDE-DTEDSEESDEELRCYSVQEPSEDSEEEPSAVPVVVAESQSARNLRSLLKMPSLLSEAFCDDLERKKKAVSFFDDVTVYLFDQESPTREAGEPFPSTKE-CPTFLEGSPGSPSATGVPLRAGHSPDSSAPEPGSRFEWDGDFPLVPG-----KAALVTALDPADPVLAAPPTPAAPFSRFTVSPAPPSRFSITQVSDSDAQSMGVSGPFGAQRTIYIYQSHCKVSLCTCSCQQNLGTRFPSTDSQPD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80YE4-1", "uniprot_id": "LMTK1_MOUSE", "id": "Q80YE4-1", "name": "Serine/threonine-protein kinase LMTK1", "aln": "------------MSSSFFNPSFAFSSHFDPDGAPLSELSWSSSLAVVAVSFSGIFTVVILMLACLCCKKGGIGFKEFENAEGDEYVADFSEQGSPAAAAQTGPDVYVLPLTEVSLPMAKQPGRSVQLLKSTDLGRHSLLYLKEIGHGWFGKVFLGEVHSGVSGTQVVVKELKVSASVQEQMQFLEEAQPYRALQHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVTESMAPDPLTLQRMACEVACGVLHLHRHNYVHSDLALRNCLLTADLTVKVGDYGLSHCKYREDYLVTADQLWVPLRWIAPELVDEVHGNLLVVDQTKSSNVWSLGVTIWELFELGAQPYPQHSDRQVLAYAVREQQLKLPKPQLQLALSDRWYEVMQFCWLQPEQRPTAEEVHLLLSYLCAKGTTELEEEFERRWRSLRPGGSTGLGSGSAAPAAATAASAELTAASSFPLLERFTS-DGFHVD-SDDVLTVTETSHGLNFEYKWEAGCGAEEYPPSGAASSPGS-AARLQELCAP----------------------DSSPPGVVPVLSAHSPSVGSEYFIRLEG-----------------AVPAAGHDPDCAG----CAPSPQ---AVTDQDNNSEESTVASLAMEPLLGHAPPTEGLWGPCDHHSHR--RQGSPCP-SRSPSPGTPMLP-----AEDIDWGVATFCPPFFDD-PLGASPSGSPGAQPSPS--DEEPEEGKVGLAAQCGHWSSN------------MSANNNSAS----------RDPESWDPGYVSSFTDSYRDDCSSLEQTPRAS--PEVGHLLSQEDPRDFLPGLVAVSPGQEPSRPFN-LLPLCPAKGLAPAACLITSPWTEGAVGGAENPIVEPKLAQEAEGSAEPQLPLPSVPSPSCE------------------GASLPSEEASAP---DILPASPTPAAGSWVTVPEPAP------------TLESSGSSLGQEAPSSE-----------------DEDTTEATSGVFTDLSSDGPHTEKSGIVPALRSLQKQVGTPDSLDSLDIPSSASDGGCEVLSPSAAGPPGGQPRAVDSGYDTENYESPEFVLKEAHES--------SEPEAFGEPASEGESPGPDPLLSVS----LGGLSKKSPYRDSAYFSDLDAESEPTFGPEKHSGIQDSQKEQDLRSPPSPGHQSVQAFPR---------------------------SAVS--------SEVLSPPQQSEEPLPE------VPRPEPLGAQGPVGVQPVPGPSHSKCFPLTSVPLISEGSGT----EPQGPSGQLSGRAQQG----------------------QMGNP----------------------------STPR--SPLCLALPGHPGALEGRP------EEDE-DTEDSEESDEELRCYSVQEPSEDSEEEPPAVPVVVAESQSARNLRSLLKMPSLLSEAFCDDLERKKKAVSFFDDVTVYLFDQESPTRETGEPFPSTKESLPTFLEGGPSSPSATGLPLRAGHSPDSSAPEPGSRFEWDGDFPLVPG-----KAALVTELDPADPVLAAPPTPAAPFSRFTVSPTPASRFSITHISDSDAQSVGGP-------------------------AAGAGGRYTEA-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZMQ8-1", "uniprot_id": "LMTK1_HUMAN", "id": "Q6ZMQ8-1", "name": "Serine/threonine-protein kinase LMTK1", "aln": "------------MSSSFFNPSFAFSSHFDPDGAPLSELSWPSSLAVVAVSFSGLFAVIVLMLACLCCKKGGIGFKEFENAEGDEYAADLAQ-GSPATAAQNGPDVYVLPLTEVSLPMAKQPGRSVQLLKSTDVGRHSLLYLKEIGRGWFGKVFLGEVNSGISSAQVVVKELQASASVQEQMQFLEEVQPYRALKHSNLLQCLAQCAEVTPYLLVMEFCPLGDLKGYLRSCRVAESMAPDPRTLQRMACEVACGVLHLHRNNFVHSDLALRNCLLTADLTVKIGDYGLAHCKYREDYFVTADQLWVPLRWIAPELVDEVHSNLLVVDQTKSGNVWSLGVTIWELFELGTQPYPQHSDQQVLAYTVREQQLKLPKPQLQLTLSDRWYEVMQFCWLQPEQRPTAEEVHLLLSYLCAKGATEAEEEFERRWRSLRPGG-GGVGPGPGAAGPMLGGVVELAAASSFPLLEQFAG-DGFHAD-GDDVLTVTETSRGLNFEYKWEAGRGAEAFP---ATLSPGR-TARLQELCAP----------------------DGAPPGVVPVLSAHSPSLGSEYFIRLEE-----------------AAPAAGHDPDCAG----CAPSPP---ATADQDDDSDGSTAASLAMEPLLGHGPPVDVPWGRGDHYPRRSLARDPLCP-SRSPSPSAGPLSLAEGGAEDADWGVAAFCPAFFED-PLGTSPLGSSGAPPLPLTGEDELEEVGARRAAQRGHWRSN------------VSANNNSGS----------RCPESWDP--VS--AGGHAEGCPSPKQTPRAS--PEPGYPGEP------LLGLQAAS-AQEPGCCPG-LPHLCSAQGLAPAPCLVTPSWTETASSGGDHPQAEPKLATEAEGTTGPRLPLPSVPSPSQE------------------GAPLPSEEASAPDAPDALPDSPTPATGGEVSAIKLAS------------ALNGSSSSPEVEAPSSE-----------------DEDTAEATSGIFTDTSSDGLQARRPDVVPAFRSLQKQVGTPDSLDSLDIPSSASDGGYEVFSPSATGPSGGQPRALDSGYDTENYESPEFVLKEAQEG--------CEPQAFAELASEGEGPGPETRLSTS----LSGLNEKNPYRDSAYFSDLEAEAEATSGPEKKCGG-DRAPGPELG-LPSTGQPSEQVCLR---------------------------PGVSGEAQGSGPGEVLPPLLQLEGSSPEPSTCPSGLVPEPPEPQGPAKVRPGPSPSCSQFFLLTPVPLRSEGNSS----EFQGPPGLLSGPAPQK----------------------RMGGP----------------------------GTPR--APLRLALPGLPAALEGRP------EEEEEDSEDSDESDEELRCYSVQEPSEDSEEEAPAVPVVVAESQSARNLRSLLKMPSLLSETFCEDLERKKKAVSFFDDVTVYLFDQESPTRELGEPFPGAKESPPTFLRGSPGSPSAPNRPQQADGSPNGSTAEEGGGFAWDDDFPLMTA-----KAAFAMALDPAAPAPAAPTPTPAPFSRFTVSPAPTSRFSITHVSDSDAESKRGP-------------------------EAGAGGESKEA-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q7U4-1", "uniprot_id": "A0A8M1Q7U4_DANRE", "id": "A0A8M1Q7U4-1", "name": "non-specific serine/threonine protein kinase", "aln": "MRSMKASAFVVVMSSVLFNPSFAFSSHFDPGGSPLSELSWPSSLAVVAVSFSGLFTFVFLMLACLCCKKGDISFKEFENTEGEEGHADLSTLASPTS--QNDPEVYILPLTEVSLPVSKQPSKSFQLLKSADLGRHSLLYIKEMGHGWFGKVLLGEVNAGLSTTQVVVKELKASASVQEQMQFLEEVQPYRVLQHPALLQCLSQSTEVTPYLLVMEHCPLGDVKGYLRSCRAADTVTPDPLILQQMACEIASGLLYLHKHNYIHSDLALRNCLLTSELAVKIGDYGLSHSKYKDDYYVTADQIWVPLRWIAPELIDEVHGNLLVVDQTKASNVWSLGVTIWELFELGNQPYRHYSDRQVLTYAVKEQQLKLPKPLLKVPLCERWYEVMQFCWLQPEQRPVVEEVHLLLSYLCSKGETEVEEDFEKRWNSLRPSLGSGSSHRTPAPEVASS------ASSSFPLLEHFSMADSFQSENGDDILTVTETSQGLNFEYKWEQARAEQPYCSSSASGPLGKNNPHYQDVYYPLCNSTGSCKGESLPLGVSPSYYESDHPGVVPVLSAHSPSVSSEYYIRIEEPVECNINLEDTDLDYSPTVEASNSSLSSAGKRSLIGSQPNSYWSAAKEPISNDYDSDSSLTMEPLQRRVP-SSVEIEQSEAYLSSNDRQHFQCEQSPKKGPDVNLIRRQGSDSNLQRRGSGSHRLEVVDDSPLGMSVSFSSPSLAHCDPYLEPNQRTAERSRANEAYYDMMSPLQKNVPRPHYMSIDIDAGDGLLLGRGSVEDDDDLFSQSMLSNWNSNHSANNNSLSDRRQAVGFQDAYFDLRHPTPSSQIGSLKSRTLEISNSFTYNSIDSLKVHSYIEATDSTPTSSNSHTDSDAGEYLHLCPEGTSGVESSAKCHSVTESLHTHTRQKNIAHKHIKNSTSDLHVGGCSILNSSTLSTEIVDVKENMLVETRISPAQKLNLATNSFGVCVKMVSCSKDTSKSVLECNRLTDSGMVPENSNITLVEINDCKDDCPDIPSGVLVDYPLD--YAEVGNIDLAHGPLQRVNRPRQAEDTINIASSCSP--CEAFSPDSYQTP-IQPKSLDSGYDTENNESPEFILKDLEGNPALSTSVESDESDMVLQMDLDEDVNVMLLHPSSSHLPLISLSERNQYRDSAYFSDYDMENDKS-PCEGSSNFFSRHEGDDIFQLKAEKQDSEKRVRREGHGTESEKGYDISMSKDKTAGLHAKQPSIKKTISNMCSSPTMVPVISTLSPFPPEMGGCLTKESTPDDGIGLESDHSGEEPNSDCYSSTTPEGSSSTQEASGMEEQANGDSKDFSSAESLGSDSTIVDFSGEIIQEEEQDICNNVDNPELPMEGHNEDNIEVNEDSMEGSSIEEALSKPRRDESLERILPALPEDLDVPAPLGNVEEADEEDSEDSDESDEELRSYNIQEQSDESDEEFPVVPVIVSDRSSARHLRSLLKMPSILTQSFCDELESKKKVVSFFDDVTVFLFDQESPTGDLGD-YSFPVEVEPNGQASDVELPRPQDGVTSYEDSSERNASEESETFQWQDDFPLMPSPSTSEPGSEEITTPPNSPVKSPDEKPAPPLSRFSVS-----RFSITHVSDPDMDSMGGN--------------------------SENGAQE--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** :*************.*:*******.************:*:.:.***********.*.******:**:* **:: .**:: *..*:**:*********::***.:*.*****:*:*******:**:*:******:****::*:* :*******:.*************.****.*:*. *****:*.:**********.*****:********.:::::*** **:****:*.*:*:**::*::************::*:**:*****:*.**::** *****:***********:****.*********:.**************** *** ::**:***:*:*:********* *::.*.:*****************..***********:** ** **:**:**.****. * . . .. . *:*******:*: *.*: : .**:*******:********* . . : : *: . * : *:: * :. *************:.***:**:* :. *:. . ..** ...* :.:.: ..: .: :**.**** : * : : : * * . .*.. : :: * .:. ..:* *** * *. : . : :. *: .:: :* : ::.. : :. :* ..: . * .: :* : . : .* : : . . . : * . : .: . ... :. ...: *: : .*.:: : *: : : : *..: ...: :. * . : . . : *. : : * * : :.. .:* .: .**::.* . * :. .: * **: . :: *:::*.**.* *.:**.: .. **:::******** *****:**: . . .: . : . .*. . . * * .*..:. ********* : * : . * .. . :: : : * : * . :. . .: * . . * . * * .. *. . *. * ..: : .* . :*. .:..* ...* .* **. * : . * :* *:***:*******.*.:** *::*:** ..***:*:: .***:*********:*:::**::** ***.*********:******** : *: :. . * *. .. * . . *.: .:.* . * *:.****:.. .: * *. :. ...*:***:** *****::**.* :* * . ", "identical_positions": 555, "similar_positions": 398, "identity": "33.37%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100812-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96FZ7-1", "uniprot_id": "CHMP6_HUMAN", "id": "Q96FZ7-1", "name": "Charged multivesicular body protein 6", "aln": "MGNLFGRK-KQSRVTEQDKAILQLKQQRDKLRQYQKRIAQQLERERALARQLLRDGRKERAKLLLKKKRYQEQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQFGNECLNKMHQVMSIEEVERILDETQEAVEYQRQIDELLAGSFTQEDEDAILEELSAITQ---------EQIELPEVPSEPLPEKIPENVPVKARPRQAELVAAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0C0A3-1", "uniprot_id": "CHMP6_MOUSE", "id": "P0C0A3-1", "name": "Charged multivesicular body protein 6", "aln": "MGNLFGRK-KQSRVTEQDRAILQLKQQRDKLRQYQKRVTQQLERERALARQLLRDGRKERAKLLLKKKRYREQLLDRTENQISSLEAMVQSIEFTQIEMKVMEGLQVGNECLNKMHQVMSIEEVERILDETQEAVEYQRQIDELLAGNFTQEDEDAILEELNAITQ---------EQMELPEVPSEPLPDRNPE-APAKARSRQAELVAAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32TRR9-1", "uniprot_id": "A0AB32TRR9_DANRE", "id": "A0AB32TRR9-1", "name": "", "aln": "MGNVFGRQGRPSRVTDQDRAILQLKQQRDKLKQYRKKITLQLERERRLAKQLLKDGKRERALLLLKKKRYQDQLLDKTDIQIDNLERLVQDIEFAQIEIKVIESLKDGNDCLKQMHEVMSLEEVEKILEDTKEAIEYQKQIDDLLAGCLKEEDEDAVLAELETLTQHFFLPPGQGEDTALSELPTDPPP-AAPE-GGTEIKTEREMLVA--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:***: : ****:**:************:**:*::: ****** **:***:**::*** ********::****:*: **..** :**.***:***:**:*.*: **:**::**:***:****:**::*:**:***:***:**** :.:*****:* **.::** *: *.*:*::* * ** .: :..: *** ", "identical_positions": 121, "similar_positions": 57, "identity": "57.35%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100812-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6GMN2-1", "uniprot_id": "BAIP2_RAT", "id": "Q6GMN2-1", "name": "BAR/IMD domain-containing adapter protein 2", "aln": "------MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTFAAKGYFDALVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKAFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPNKIPDRAAQLMQQMAN-SNGSILPSALSASKS------------------------------------------------------------------------NLVIS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------DPIPGAKPLPVPP-----------------------ELAPFVG----RMSAQENVPVMNGVAGADSED-------------------------YNPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNS------YATTENKTLPRSSSMAAGLERN-----------------GRMRVKAIFSHAAGDN-------------------STLLSFKEGDLITLLVPEARDG----WHYGESEKTKMRGWFPFSYTRVLDSDGSDRLHMSLQQ--------------------------------------------------------GKSSSTGNLLDKDDLALPPPDYGTSSRAFPSQTAGTFKQRPYSVAVPAFS-QGLDDYG----ARSVS--------------------------------------------------------------------------RNPFANVHLKPTVTNDR----------------SAPLLS--------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BKX1-1", "uniprot_id": "BAIP2_MOUSE", "id": "Q8BKX1-1", "name": "BAR/IMD domain-containing adapter protein 2", "aln": "------MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTFAAKGYFDALVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEETLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPNKIPDRAVQLMQQMAN-SNGSILPSALSASKS------------------------------------------------------------------------NLVIS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------DPIPGAKPLPVPP-----------------------ELAPFVG----RMSAQENVPVMNGVAGPDSED-------------------------YNPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNS------YATTENKTLPRSSSMAAGLERN-----------------GRMRVKAIFSHAAGDN-------------------STLLSFKEGDLITLLVPEARDG----WHYGESEKTKMRGWFPFSYTRVLDSDGSDRLHMSLQQ--------------------------------------------------------GKSSSTGNLLDKDDLALPPPDYGTSSRAFPTQTAGTFKQRPYSVAVPAFS-QGLDDYG----ARSVS--------------------------------------------------------------------------RNPFANVHLKPTVTNDR----------------SAPLLS--------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UQB8-1", "uniprot_id": "BAIP2_HUMAN", "id": "Q9UQB8-1", "name": "BAR/IMD domain-containing adapter protein 2", "aln": "------MSLSRSEEMHRLTENVYKTIMEQFNPSLRNFIAMGKNYEKALAGVTYAAKGYFDALVKMGELASESQGSKELGDVLFQMAEVHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAELKKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENYVSDGYKTALTEERRRFCFLVEKQCAVAKNSAAYHSKGKELLAQKLPLWQQACADPSKIPERAVQLMQQVA--SNGATLPSALSASKS------------------------------------------------------------------------NLVIS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------DPIPGAKPLPVPP-----------------------ELAPFVG----RMSAQESTPIMNGVTGPDGED-------------------------YSPWADRKAAQPKSLSPPQSQSKLSDSYSNTLPVRKSVTPKNS------YATTENKTLPRSSSMAAGLERN-----------------GRMRVKAIFSHAAGDN-------------------STLLSFKEGDLITLLVPEARDG----WHYGESEKTKMRGWFPFSYTRVLDSDGSDRLHMSLQQ--------------------------------------------------------GKSSSTGNLLDKDDLAIPPPDYGAASRAFPAQTASGFKQRPYSVAVPAFS-QGLDDYG----ARSMS--------------------------------------------------------------------------RNPFAHVQLKPTVTNDRCDLSAQGPEGREHGDGSARTLAGR------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GYK7-1", "uniprot_id": "A0AC58GYK7_DANRE", "id": "A0AC58GYK7-1", "name": "BAR/IMD domain-containing adapter protein 2", "aln": "MVLTQASKMSRTDEVHRITENVYKSIMEQFNPCLRNFVAMGKTYEKALSSVTFAAKGYFDALVRMGELASESHGSKDLGDVLFQMAEVHRQIQMQLEDMLKSFHNELLTELEKKVELDVRYLNAALKKYQMEHKSKGESLEKCQAELKKLRRKSQGSKNPSKYGDKEMQYVETISSKQNELDNYISESYKNALSEERRRYCFLVDRQCAVAKTSNTYHTKGRDLLTQKIPLWQQACADPNKLPERAMLLAQQMSSGAAGTLGPSVHHTSKS------------------------------------------------------------------------NLTIS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------DPIPGAKPLPVPP-----------------------ELAALMGNQQSRMMGADSVPIVNGSGVHVGED-------------------------YQRWMETRAAHDKQSQQPHRHG--GESFSNTLPVRKVAPVKPK------NTLAETQTLPRSSSMTTGLERN-----------------GRTRVQALFSHAAGDN-------------------STLLSFTEGDIITLLVPEARDG----WHYGENEKNRMRGWFPFSYTRLIAEPDSNKLHVSLQH--------------------------------------------------------NRSSSTGNLLER-EMALPTPDYGMPTRFAQQQSTAHSRQRPYSVAVPGFSQQGLEEYESRFQARTMD--------------------------------------------------------------------------PLQFSTFALT-SRQRQRNAASKQKPKLIITEELGSRLLH--------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQE6-1", "uniprot_id": "Q8IQE6_DROME", "id": "Q8IQE6-1", "name": "", "aln": "---------MEAEEVTKLVDGVYRNILDRFNPGARQLIAAGKSYLKALHGAATASRLFNEALAKIAMNAQQS-GTGDIGSALMSVVNVNKEIQDQQMNILKAFYVDLLVPLETNLEKDTKVVQHEQKKFLQQHKVRMESYQKAVSTMKKQRKKKATPEN----TEKELRSLQLLEDQKKKLDVFCDQSYKNAMTQERRRYGFVLERQCSIAKHWMVYHTTGKTVIDNNFENWQEIAASREIIPPAAYESGYSTSNGHNNNNISSSSSSGNNNTSGNMRRLERIKDGDDDHLQGHGAQLKKSRSIDAPYGDMRTLHERENLSGLGGTGPAHYAQNSLPRAKSDFNLALVGTGQSSANKHKIIEEQLATLGDDQRGDQRPLVKALYAYMPSGENQLSFEEGDRIALVGGKAKGWQFGENLRTQHFGWFPVAYTNAEVAEVTTSGGRRYENMLMSYERNGGGSGSGSGGGGLRSYQQQQDYEAQLELMESHEATYRRRRNHSAEDSSPTRMFGDTIKQQKKYRPGSGANPRPGPPPTLPAPVPNGPQSQSSRMLNSSQSFCASNGGGVNAAVERRKQKLLNGVQSSKNHPSGKSGVAAKTSLHSSNDSGFANEPPPQPEVDYSDEEPATQRVAIRRRADTNSHTNTVPRDVASWTLNRNFRNSVDSQIDDKSLHRLSRQSGGVGKMRYDLIASDDEILQASSAGLKRTKSFWKFGGGRNGEDILAGMSLWQHRDLVAAPNLEEMRDRDDLERRLEEDRNGTLTKSHNSSSSQEKRERKDSLTSTELYGDEDENIYGVSPQQPPLQQQTQQHQQHQQHQQQQAQQHRSSYTPKSRMKIMKTIEIDIEEPTEAERMSTMRRGQSQDQQQQHRKLDKQVSGTGSQHKSLTLSRTKSNQQQQQQQQFPQSTDEGESDEHGTLKLSDVNNFFDGEGKNNSHGHGLVMKTVKRQDILKQYYTSEDEEDSDAELKSTSSDPYDCIVINDHLVRKDDKMRRHHQQQHQQMATNTLKKSSSKDQDSTLTRNSTASSGAPTATILPRTRLLKSSTSAGNNIGNSSATLERNSKGLAGNKSYGPWYDFWDQEQHGQKSASAKLK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::*: ::.:.**:.*:::*** *:::* **.* *** ..: *:: : :**.::. *.:* *: ::*..*:.:.:*:::** * : **:*: :**. ** ::* * : :. **: ::: : :: :*. : :** *:*. .:* :**:: :: :..:: :*: : .:.**.*:::****: *::::**::** .**:.*: :: ::: **: .*. . :* * . : . .* :.:. **.: * .**:* * ** .:.. * . ::** .. . : . . : :*.:**:* : : ::* * * : *: : * *.::::....* * ..* .: : * : : * *:* * ....: : . .:: *.: . ..: :* *: :..* .: :: .: .. * : . : :*: . .* : :* .: :. :: *. : .:: .: ", "identical_positions": 107, "similar_positions": 215, "identity": "9.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100818-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B6ID01-1", "uniprot_id": "TM216_RAT", "id": "B6ID01-1", "name": "Transmembrane protein 216", "aln": "-----------------MAPRDKR--LSSTPLEILFFLNGWYYATYFLLELLIFLYKGLLLPYPTANLVLDVVMLLLYLGIEVIRLFFGTKGNLCQRKMPLGISVALTFPSAMMASYYLLLQTYVLRLEAIMNSILLFFCGSELLLEMLTLATFSSMDRI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQC4-1", "uniprot_id": "TM216_MOUSE", "id": "Q9CQC4-1", "name": "Transmembrane protein 216", "aln": "-----------------MAPRDKR--LSSTPLEVLFFLNGWYYATYFLLELLIFLYKGLLLPYPTANLVLDVVMLLLYLGIEVIRLFFGTKGNLCQRKMPLGISVALTFPSAMMASYYLLLQTYVLRLEAIMNSILLFFCGSELLLEMLTLATFSSMDRI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P0N5-1", "uniprot_id": "TM216_HUMAN", "id": "Q9P0N5-1", "name": "Transmembrane protein 216", "aln": "----------MLPRGLKMAPRGKR--LSSTPLEILFFLNGWYNATYFLLELFIFLYKGVLLPYPTANLVLDVVMLLLYLGIEVIRLFFGTKGNLCQRKMPLSISVALTFPSAMMASYYLLLQTYVLRLEAIMNGILLFFCGSELLLEVLTLAAFS---RI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EYQ9-1", "uniprot_id": "TM216_DANRE", "id": "E7EYQ9-1", "name": "Transmembrane protein 216", "aln": "MADVCLRLQYACPWQSNMAAHGRQPVLSSTPLQILFHLNGWYFAAFFVAEILMFIYKGVILPYPQDNLILDVVLLLLFSGLETLRLFYGWKGNLCQRSLALFVSVAILVPCAVLSVYYLLLQTFVLRLEFVLNAVLLCFYGFELVLGVMTISIFSRANIY-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHN0-1", "uniprot_id": "Q9VHN0_DROME", "id": "Q9VHN0-1", "name": "", "aln": "----------------------MN---ASLIYEILMYLNSFYFGMYAAFEVGVGVLKAINLNYGENALSREASILLSLCIIETVRIVFGRKSSLSDRGWQATASVILTLPSLAIVIYLCCFQTFVLKLEIILSALMITLQGAELVYASIFICTMCRPVTYT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8INQ3-1", "uniprot_id": "Q8INQ3_DROME", "id": "Q8INQ3-1", "name": "Transmembrane protein 216", "aln": "---------MPPKRPPPLVPKKPN---PSMNYEVLIYLNSFYFGMFACCEMAMGLLKAINLSYTGHTLALDTGVMISFIVFETIRLIMGRMSSLADRGWSAILSVFMTAPCFVGVSYLLLLQTYRLRLEYCLCTLQIALYLTEVWYAIVFVFSLCRPVTYD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .* ::*:.**.:* . : *: : : *.: * * * :. ::: :*.:*:. * ..*.:* ** : *. * :**: *:** : : : : *: : : :. ", "identical_positions": 25, "similar_positions": 43, "identity": "15.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100818-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P46720-1", "uniprot_id": "SO1A1_RAT", "id": "P46720-1", "name": "Solute carrier organic anion transporter family member 1A1", "aln": "------------------------------------------------------------------------------------------------MEETEKKIA--------------------------------------------------TQEG--------RLFSKMKVFLLSLTCACLTKSLSGVYMNSMLTQIERQFDISTSVAGLINGSFEIGNLFFIVFVSYFGTKLHRPVVIGIGCVIMGLGCLLMSLPHFFMGRYEYETTISPTGN---LSSNSFLCMENRTQTLKPTQDP-----------AECVKEMKS---------LMWICVMVGNIIR-GIGETPIVPLGISYIEDFAKSENSPLYIGILEMGKVAGPIFGLLLGSYCAQIYVDIGSVNTDDLTITPSDTRWVGAWWIGFLVCAGVNILTSIPFFFLPKALPKKGQQENVA----------------------VTKDGKVEKYGGQAREENLGITK---DFLTFMKRLFCNPIYMLFILTSVLQVNGFINKFTFLPKYLEQQYGKSTAEAIFLIGVYSLPPICLGYLIGGFIMKKFKITVKKAAYLAFCLSVFEYLLFLCHFMLTCDNAAVAGLTTSYKGVQHQLHVESKVLADCNTRCSCSTNTWDPVCGD-NGVAYMSACLAGCKKFVGTGTN--MVFQDCSCIQSLG--------------------------------------------------------NSSAVLGLCKKGPECANRLQYFLILTIIISFIYSLTAIPGYMVFLRCVKSEEKSLGVGLHTFCIRVFAGIPAPVYFGALIDRTCLHWGTLKCGQRGACRMYDINSFRHIYLGLPIALRGSSYLPAFFILILMRKFQFPGDIDSSATDHTEMMLGEKESEHTDVHGSPQVENDGELKTKL--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXZ6-1", "uniprot_id": "SO1A1_MOUSE", "id": "Q9QXZ6-1", "name": "Solute carrier organic anion transporter family member 1A1", "aln": "------------------------------------------------------------------------------------------------MEETEKKVA--------------------------------------------------TQEG--------RFFSKMKVFLMSLTCAYLAKSLSGVYMNSMLTQIERQFGIPTSVVGFITGSFEIGNLLLIVFVSYFGRKLHRPIIIGVGCVVMGLGCFLMASPHFLMGRYKYETTISPTSN---LSSNSFLCIENRTQTLKPTQDP-----------TECVKEIKS---------LMWIYVLIGNTMR-GIGETPIMPLGISYIEDFAKSENSPLYIGILEMGKIVGPIIGLLLGSFFARVYVDIGSVNTDDLTITPTDTRWVGAWWIGFLVCAGVNILTSIPFFFFPKTLPKKELQDNVD----------------------VTKYEKVEKHRERAKKENLGITK---DFLPFMKSLCCNPIYMLFSLTSVLQINGFASTFTFLPKYLEQQYGKSTSEAVFLIGVYSLPPVCLGYLISGFIMKKFKITVKKAAYIAFGLSLSEYFIFLCNYLLTCDNFPVAGLTTSYKGVQHPLYGEKNVLADCNTRCSCLTDTWDPVCGD-NGLAYMSACLAGCEKSVGTGTN--MVFQNCSCIGSSG--------------------------------------------------------NSSAVLGLCKKGPECDNKLQYFLIKSVFSSFIFSLAAIPGYMVLLRCVKSEEKSIGVGLHAFFIRLLAGIPAPVYFGALIDRTCLHWGTLKCGQPGACRMYDINRFRHIYLGLPAAVRGSSFLPAVFILILMRKFHFPGDIHSPDTELAEMKLTEKESECTDVCRSPKVENDGELKTKL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88397-1", "uniprot_id": "SO1A5_RAT", "id": "O88397-1", "name": "Solute carrier organic anion transporter family member 1A5", "aln": "------------------------------------------------------------------------------------------------MGETEKRVA--------------------------------------------------THEV--------RCFSKIKMFLLALTWAYVSKSLSGIYMNTMLTQIERQFDIPTSIVGFINGSFEIGNLLLIIFVSYFGTKLHRPIMIGVGCVIMGLGCFLMSLPHFLMGRYEYETTISPTSN---LSSNSFLCMENRSQTLKPTQDP-----------AECIKEMKS---------LMWIYVLVGNIIR-GIGETPIMPLGISYIEDFAKSENSPLYIGILETGKVFGPIVGLLLGSFCASIYVDTGSVNTDDLTITPTDTRWVGAWWIGFLICAGVNILSSIPFFFFPKTLPKEGLQDDVD----------------------GTNNDKEEKHREKAKEENRGITK---DFLPFMKSLSCNPIYMLLILTSVLQINAFINMFTFLPKYLEQQYGKSTAEVVLLIGVYNLPPICIGYLLIGFIMKKFKITVKKAAYMAFCLSLFEYLLYFLHFMITCDNFPVAGLTASYEGVHHPLYVENKVLADCNRGCSCSTNSWDPVCGD-NGLAYMSACLAGCKKSVGTGTN--MVFQNCSCIRSSG--------------------------------------------------------NSSAVLGLCKKGPECANKLQYFLIMSVIGSFIYSITAIPGYMVLLRCIKPEEKSLGIGLHAFCTRVFAGIPAPIYFGALIDRTCLHWGTLKCGEPGACRMYNINNFRRIYLVLPAALRGSSYLPALFILILMRKFQFPGEIDSSETELAEMKITVKKSECTDVHGSPQVENDGELKTRL--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YY5-1", "uniprot_id": "SO1A5_MOUSE", "id": "Q91YY5-1", "name": "Solute carrier organic anion transporter family member 1A5", "aln": "------------------------------------------------------------------------------------------------MGETEKRIA--------------------------------------------------THGV--------RCFSKIKMFLLALTCAYVSKSLSGIYMNSMLTQIERQFDIPTSIVGLINGSFEIGNLLLIILVSYFGTKLHRPIMIGIGCVIMGLGCFLMSLPHFLMGRYEYETTISPTSN---LSSNSFLCMENRTQTLKPTQDP-----------AECVKEMKS---------LMWIYVLVGNIIR-GIGETPIMPLGISYIEDFAKSENSPLYIGILESGKMIGPIVGLLLGSFCARIYVDTGSVNTDDLTITPTDTRWVGAWWIGFLVCAGVNILTSIPFFFFPKTLPKEGLQDNVA----------------------RTENDKEEKHREKAKEENRGITK---DFLPFMKSLSCNPIYMLLILTSVLQINAFINMFTFLPKYLEQQYGKSTSEVVLLIGVCNLPPICIGYLLIGFIMKKFRITVKKAAYMAFCLSLFEYLLSYFHFMISCDNFQVAGLTTSYEGVQHPLYVENKVLADCNTRCSCLTNTWDPVCGD-NGLSYMSACLAGCEKSVGMGTH--MVFQNCSCIQSSG--------------------------------------------------------NSSAVLGLCKKGPECANKLQYFLIMSVIGSFIYSITAIPGYMVLLRCIKSEEKSLGIGLHAFCTRIFAGIPAPIYFGALIDRTCLHWGTLKCGEPGACRIYNINNFRRIYLVLPAALRGSSYLPAFFILILMRKFQLPGEMYSSETELADMKQTVKKSECTDVHGIPKVENDGELKTKL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0QWR8-1", "uniprot_id": "M0QWR8_MOUSE", "id": "M0QWR8-1", "name": "Solute carrier organic anion transporter family member", "aln": "------------------------------------------------------------------------------------------------MEEPEKKIA--------------------------------------------------THGV--------RCFAKIKMFLMALTWAYVSKSLSGTYMVSMLTQIERQFDIPASIAGLISGSFGIGNLLLIVFVNYFGMQLHRPIIIGVGCATMGLGCFLISLPHFLMGIYEYETMISPASN---LPSNSFLCVENRSQTLKPTQDP-----------AECVKEIKS---------SMWIYVLVGNIIR-GIGETPLLPLGVSYIEDFAKSENSPLYIGILETGKMFGPVIGLLLGSFCASIYVDTGSVNTDDLTITPTDTRWVGAWWIGFLVCAGVNVLTSIPFFFFPKTLPEEGLQDNGD----------------------GTENDKEEKHREKAKEENRGITK---DFFPFMKSLSCDPIYVLFILISVLQISTFTSTFNFLSKYLEQQFGKSTAEVVFFIGLYTLPTICIGYLIAGFIMKKFKITVKKAAYLAFCLSLCEYLFGFCNFLIACDNVPVSGLTISYEGVQHPLYVENNVLADCNTRCSCLTKTWDPVCGD-NGLSFMSACHTGCEKSVGTGIN--MVFQNCSCIGSSG--------------------------------------------------------KPSAVLGLREKGPECANKLQHLLILSVFLSVIYSLSATPGYTVLLRCVESEEKSPGVGIHTFCTRVFGGIPAPVYIGALLDRTCLHWGTQKCGEPGACRMYDINSFRSIYLGLPAALRGISYLPAFIIVILIRKFCLPGEINSSEMEIAEMKLAEMESECTDAHRSHKFKSDGELKTKL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O35913-1", "uniprot_id": "SO1A4_RAT", "id": "O35913-1", "name": "Solute carrier organic anion transporter family member 1A4", "aln": "------------------------------------------------------------------------------------------------MGKSEKRVA--------------------------------------------------THGV--------RCFAKIKMFLLALTCAYVSKSLSGTYMNSMLTQIERQFGIPTSIVGLINGSFEIGNLLLIIFVSYFGTKLHRPIMIGVGCAVMGLGCFLISLPHFLMGQYEYET-ILPTSN---VSSNSFFCVENRSQTLNPTQDP-----------SECVKEMKS---------LMWIYVLVGNIIR-GIGETPIMPLGISYIEDFAKSENSPLYIGILETGMTIGPLIGLLLASSCANIYVDIESVNTDDLTITPTDTRWVGAWWIGFLVCAGVNILTSFPFFFFPKTLPKEGLQENVD----------------------GTENAKEKKHRKKAKEEKRGITK---DFFVFMKSLSCNPIYMLFILISVLQFNAFINSFTFMPKYLEQQYGKSTAEVVFLMGLYMLPPICLGYLIGGLIMKKFKVTVKKAAHLAFWLCLSEYLLSFLSYVMTCDNFPVAGLTTSYEGVQHQLYVENKVLADCNTRCNCSTNTWDPVCGD-NGLAYMSACLAGCEKSVGTGTN--MVFQNCSCIQSSG--------------------------------------------------------NSSAVLGLCNKGPDCANKLQYFLIIAIFGCFIYSLAGIPGYMVLLRCIKSEEKSLGVGLHAFCIRILAGIPAPIYFGALIDRTCLHWGTLKCGEPGACRMYDINSFRRLYLGLPAALRGASFVPAFFILRLTRTFQFPGDIESSKTDHAEMKLTLKESECTEVLRSKVTED----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EP96-1", "uniprot_id": "SO1A4_MOUSE", "id": "Q9EP96-1", "name": "Solute carrier organic anion transporter family member 1A4", "aln": "------------------------------------------------------------------------------------------------MGKSEKEVA--------------------------------------------------THGV--------RCFSKIKAFLLALTCAYVSKSLSGTYMNSMLTQIERQFGIPTSVVGLINGSFEIGNLLLIIFVSYFGTKLHRPIMIGVGCAVMGLGCFLISIPHFLMGRYEYETTILPTSN---LSSNSFVCTENRTQTLKPTQDP-----------TECVKEMKS---------LMWIYVLVGNIIR-GMGETPIMPLGISYIEDFAKSENSPLYIGILETGMTIGPLIGLLLGSSCANIYVDTGSVNTDDLTITPTDTRWVGAWWIGFLVCAGVNILTSIPFFFFPKTLLKEGLQDNGD----------------------GTENAKEEKHREKIKEENRGITK---DFFLFMKSLSCNPIYMIFILISVIQVNAFINSFTFMPKYLEQQYGKSTAEIVFLMGLYMLPPICLGYLIGGLIMKKFKITVKKAAYIGFWLSLTEYLLSFVSYIMTCDNFPVAGLTTSYEGVQHPLYVENNVLADCNTKCSCLTNTWDPVCGD-NGLSYMSACLAGCEKSVGTGTN--MVFQNCSCIQSSG--------------------------------------------------------NASAVLGLCDKGPECANKLQYFLIISIIGCFIFSLGAIPGYMVLLRCMKSEEKSLGVGLHTFCMRILGGIPAPIYFGALIDRTCLHWGTLKCGEPGACRMYDINSFRRIYLGLPAALRGASFLPALFILILMRKFQFPGDIDSSDTDPAEMKLTAKESKCTNVHRSPTMQNDGERKTKL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9QYE2-1", "uniprot_id": "SO1A6_RAT", "id": "Q9QYE2-1", "name": "Solute carrier organic anion transporter family member 1A6", "aln": "------------------------------------------------------------------------------------------------MGEPEKRAG--------------------------------------------------THGI--------RCFAKIKVFLLALTWAYASKALSATYMNSMLTQIERRFNISTSIVGLINGSFEVGNLLLIIFVSYFGRKRHRPIMIGIGCAVMGLGCFIISLPHFLMGRYEYETTISPTSN---LSSNSFLCMENRTQTLKPTQDP-----------AECVKEMKS---------LMWIYVLVGNIIR-GIGETPIMPLGISYIEDFAKSENSPFYIGILEVGKITGPIAAIWLGSFCATIYVDMGSVNTDDLTITPTDTRCVGAWWIGFLVCAGLNILISIPFFFFPKTFPKEGPEDMAN----------------------ETKNDEGDKHREKAKEEKRGITK---DFFLFMKSLSCNPIYMLCVLTSVLQVNGFVSIFTFKPKYLEHHYGKSSSEAIFLMGLYTLPSVCVGYLISGFIMKKFKITLKKAAFISYCLGMSECLLSLCNFMLTCDNVPIAGLTTSYEGIQQSFDMENTVLADCNTRCSCLTKTWDPVCGD-NGLAYITPCLAGCEKSVGSGIN--MVLQDCSCIQSSG--------------------------------------------------------NSSAVLGLCNKGPDCANKLQYFLIITVFCSFFYSLSLIPGYMIFLRCMKSEEKSLGIGLQAFCMRILGGILAPIYFGVLIDRTCLHWGTQKCGEPGACRTYEINSFRSIYLGLPAALRGSSYLPAFFILRLMRKFQFPGDINSPVTDHVEMMLTEKESEHTDVHRSPQVENDGELKTKL--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J94-1", "uniprot_id": "SO1A6_MOUSE", "id": "Q99J94-1", "name": "Solute carrier organic anion transporter family member 1A6", "aln": "------------------------------------------------------------------------------------------------MGEPGKRVG--------------------------------------------------IHRV--------RCFAKIKVFLLALIWAYISKILSGVYMSTMLTQLERQFNISTSIVGLINGSFEMGNLLVIVFVSYFGTKLHRPIMIGVGCAVMGLGCFIISLPHFLMGRYEYETTISPTSN---LSSNSFLCVENRSQTLKPTQDP-----------AECVKEIKS---------LMWIYVLVGNIIR-GIGETPIMPLGISYIEDFAKSENSPLYIGILEVGKMIGPILGYLMGPFCANIYVDTGSVNTDDLTITPTDTRWVGAWWIGFLVCAGVNVLTSIPFFFFPKTLPKEGLQDNGD----------------------GTENAKEEKHRDKAKEENQGIIK---EFFLMMKNLFCNPIYMLCVLTSVLQVNGVANIVIYKPKYLEHHFGISTAKAVFLIGLYTTPSVSAGYLISGFIMKKLKITLKKAAIIALCLFMSECLLSLCNFMLTCDTTPIAGLTTSYEGIQQSFDMENKFLSDCNTRCNCLTKTWDPVCGN-NGLAYMSPCLAGCEKSVGTGAN--MVFQNCSCIRSSG--------------------------------------------------------NSSAVLGLCKKGPDCANKLQYFLIITVFCCFFYSLATIPGYMVFLRCMKSEEKSLGIGLQAFFMRLFAGIPAPIYFGALIDRTCLHWGTLKCGEPGACRTYEVSSFRRLYLGLPAALRGSIILPSFFILRLIRKLQIPGDTDSSEIELAETKPTEKESECTDMHKSSKVENDGELKTKL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "L7N264-1", "uniprot_id": "L7N264_MOUSE", "id": "L7N264-1", "name": "Solute carrier organic anion transporter family member", "aln": "------------------------------------------------------------------------------------------------MEETETRIL--------------------------------------------------TRGV--------RCFSKVKVFLLALTGACVSKSLTGSHMKSMLLQIERQFGLLTSTVGLITGSFSMGMLLVIIPVSYFGTKLHRPIMIGVGCMFMGLGCFIISLPHFLMGRYEYETTISPTSN---LSSNSFLCMENRSLTLKPTQDT-----------TECGREIKS---------LMWIYVLVGNIIR-GMGETAIMPLGISYIEDFAKSENSPLYIGILEIGITISYWIGYSLGSFCANIYVDTDSGNTDDLTITPTDTRWVGAWWIGFLVCAGVNFLTSIPFFFFPKTLPKEGLQDNGD----------------------GTENAKEEKHREKAKKENQRIIK---DFFPLMKNLSCNPIYMLYLLISVLQFNTFVSMVSYVPKYLEQQYGKSSADVLFIMGIYMLPPICLGYLLGGLIMKKFKITAKKAAYIAFCLSLTDYLLSLSNYMTNCDSFQVAGLTASYEGVQHPLHVDHEVLADCNTRCSCLTNTWDPVCGN-NGLAYMSACLAGCEKSVGNGIN--MVFQNCSCIRSSG--------------------------------------------------------NSSAVLGLCNKGPDCDNMLKYFIIIFSVKMFIFSLSSIPGYMVLLRCMKPEEKSLGVGLHTFCTKIFAGIPAPIYFGALIDRACLHWGTLKCGEKAACRIYDINSFRYLFFGLPAALTGSSYLPAVFLLRLMRTFQLPEDTDSPDTELAETKLIEKENDCTDVHRSPKFESNGEMKAKL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46721-1", "uniprot_id": "SO1A2_HUMAN", "id": "P46721-1", "name": "Solute carrier organic anion transporter family member 1A2", "aln": "------------------------------------------------------------------------------------------------MGETEKRIE--------------------------------------------------THRI--------RCLSKLKMFLLAITCAFVSKTLSGSYMNSMLTQIERQFNIPTSLVGFINGSFEIGNLLLIIFVSYFGTKLHRPIMIGIGCVVMGLGCFLKSLPHFLMNQYEYESTVSVSGN---LSSNSFLCMENGTQILRPTQDP-----------SECTKEVKS---------LMWVYVLVGNIVR-GMGETPILPLGISYIEDFAKFENSPLYIGLVETGAIIGPLIGLLLASFCANVYVDTGFVNTDDLIITPTDTRWVGAWWFGFLICAGVNVLTAIPFFFLPNTLPKEGLETNAD----------------------IIKNENEDKQKEEVKKEKYGITK---DFLPFMKSLSCNPIYMLFILVSVIQFNAFVNMISFMPKYLEQQYGISSSDAIFLMGIYNLPPICIGYIIGGLIMKKFKITVKQAAHIGCWLSLLEYLLYFLSFLMTCENSSVVGINTSYEGIPQDLYVENDIFADCNVDCNCPSKIWDPVCGN-NGLSYLSACLAGCETSIGTGIN--MVFQNCSCIQTSG--------------------------------------------------------NSSAVLGLCDKGPDCSLMLQYFLILSAMSSFIYSLAAIPGYMVLLRCMKSEEKSLGVGLHTFCTRVFAGIPAPIYFGALMDSTCLHWGTLKCGESGACRIYDSTTFRYIYLGLPAALRGSSFVPALIILILLRKCHLPGENASSGTELIETKVKGKENECKDIYQKSTVLKDDELKTKL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9NPD5-1", "uniprot_id": "SO1B3_HUMAN", "id": "Q9NPD5-1", "name": "Solute carrier organic anion transporter family member 1B3", "aln": "------------------------------------------------------------------------------------------------MDQHQHLNK--------------------------------------------------TAESASSEKKKTRRCNGFKMFLAALSFSYIAKALGGIIMKISITQIERRFDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGSILTSLPHFFMGYYRYSKETHINPS---ENSTSSLSTCLINQTLSFNGTSPEI------VEKDCVKESGS---------HMWIYVFMGNMLR-GIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKNPNKPQKERKISL-----------------SLHVLKTNDD-RNQTANLTNQGKNVTKNVTGFFQSLKSILTNPLYVIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIKKFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSYCNSECNCDESQWEPVCGN-NGITYLSPCLAGCKSSSGIKKH--TVFYNCSCVEVTGLQN----------------------------------------------------RNYSAHLGECPRDNTCTRKFFIYVAIQVINSLFSATGGTTFILLTVKIVQPELKALAMGFQSMVIRTLGGILAPIYFGALIDKTCMKWSTNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALVLYIVFIFAMKKKFQGKDTKASDNERKVMDEANLEFLNNGEHFVPSAGTDSKTCNLDMQDNAAAN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Y6L6-1", "uniprot_id": "SO1B1_HUMAN", "id": "Q9Y6L6-1", "name": "Solute carrier organic anion transporter family member 1B1", "aln": "------------------------------------------------------------------------------------------------MDQNQHLNK--------------------------------------------------TAEAQPSENKKTRYCNGLKMFLAALSLSFIAKTLGAIIMKSSIIHIERRFEISSSLVGFIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCFIMGIGGVLTALPHFFMGYYRYSKETNINSS---ENSTSTLSTCLINQILSLNRASPEI------VGKGCLKESGS---------YMWIYVFMGNMLR-GIGETPIVPLGLSYIDDFAKEGHSSLYLGILNAIAMIGPIIGFTLGSLFSKMYVDIGYVDLSTIRITPTDSRWVGAWWLNFLVSGLFSIISSIPFFFLPQTPNKPQKERKASL-----------------SLHVLETNDE-KDQTANLTNQGKNITKNVTGFFQSFKSILTNPLYVMFVLLTLLQVSSYIGAFTYVFKYVEQQYGQPSSKANILLGVITIPIFASGMFLGGYIIKKFKLNTVGIAKFSCFTAVMSLSFYLLYFFILCENKSVAGLTMTYDGNNPVTSHRDVPLSYCNSDCNCDESQWEPVCGN-NGITYISPCLAGCKSSSGNKKP--IVFYNCSCLEVTGLQN----------------------------------------------------RNYSAHLGECPRDDACTRKFYFFVAIQVLNLFFSALGGTSHVMLIVKIVQPELKSLALGFHSMVIRALGGILAPIYFGALIDTTCIKWSTNNCGTRGSCRTYNSTSFSRVYLGLSSMLRVSSLVLYIILIYAMKKKYQEKDINASEN-GSVMDEANLESLNKNKHFVPSAGADSETHC----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3V0H7-1", "uniprot_id": "SO1B7_HUMAN", "id": "G3V0H7-1", "name": "Putative solute carrier organic anion transporter family member 1B7", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKISTTQIERRFEISSSLVGLIDGSFEIGNLFVIVFVSYFGSKLHRPKLIGIGCFLMGTGSILMALPHFFMGYYRYSKETNIDPS---ENSTSNLPNCLINQMLSLNRTPSEI------IERGCVKESGS---------HMWIYVFMGNMLR-GIGETPIVPLGISYIDDFAKEGHSSLYLGTVNVMGMTGLVFAFMLGSLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGIVSIISSIPFFFLPLNPNKPQKERKVSL-----------------FLHVLKTNDK-RNQIANLTNRRKYITKNVTGFFQSLKSILTNPLYVIFVIFTLLHMSSYIASLTYIIKMVEQQYGWSASKTNFLLGVLALPAVAIGMFSGGYIIKKFKLSLVGLAKLAFCSATVHLLSQVLYFFLICESKSVAGLTLTYDGNSPVRSHVDVPLSYCNSECNCDESQWEPVCGN-NGITYLSPCLAGCKSSSGNKEP--IVFYNCSCVEVIGLQN----------------------------------------------------KNYSAHLGECPRDDACTRKSYVYFVIQVLDAFLCAVGLTSYSVLVIRIVQPELKALAIGFHSMIMRSLGGILVPIYFGALIDTTCMKWSTNSCGARGACRIYNSTYLGRAFFGLKVALIFPVLVLLTVFIFVVRKKSHGKDTKVLENERQVMDEANLEFLNDSEHFVPSAEEQ---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7C1-1", "uniprot_id": "A0ACD6B7C1_DANRE", "id": "A0ACD6B7C1-1", "name": "Solute carrier organic anion transporter family member", "aln": "-------------------------------------------------------------------------------------------MSEPTIEDNGKPTS--------------------------------------------------QQELCSPEAPEEPRCSSLKIFIGALSFAYFSKTLCGTYMKSAITQIERRFDLSSSAVGLVDGSFEMGNLLFVAVVSHFGARLHRPRLIGMGCFLMAIGSALTGLPHVFMGRYKFDTAVQGFAN---ETVVIAPCQYPTNPSEHSIQHIDNT------TGTDCVKDPGS---------SMWIYVFLGNALR-GIGETPVTPLGISYIDDFAKAENSAFYISCLQTIMLLGPMFGFLLGSMCAKLYVDIGFVSVDSVSITPQDARWVGAWWLGFFVSSAFLVLSGVPFWFLPRSLPKQGEEEKE----------------------IYNTDDANKEHSVLQTTHTMTLADIAKGFLPSLKRLLCTPAYFLLLCGIVLKFNSFIGLLTFKAKYMEQQFGQSASRANFLIGVLILPVVAVGIFLGGLLMKKYKLSVVAGAQLSFITSFTAFLLLLLHFGTKCDNVPVAGLTVSYNGTPYMPSDQRSLESQCNQDCSCSTSEWDPVCSD-SGITYMSPCLAGCTASTGQGKN--TVFHNCSCVLSPSPAE----------------------------------------------------GGRSVSLGQCPQGSACARSFTSYMAVSVLSSFINSLGTTPGYMIIIRCIAPELKSLALGIQTLVMRTLGGIPAPIYFGALIDTTCLKWGLKKCGGRGACRIYDSNMYRVIFLSLTTALSGCSYFFIIAVIVLLRRQFIKEEVKALQQMAGKQNEIELRSPEMQNPDGTKTDERDKNNTEG--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W270-1", "uniprot_id": "Q9W270_DROME", "id": "Q9W270-1", "name": "Solute carrier organic anion transporter family member", "aln": "------------------------------------------------------------------------MASE----EIEASKFLKDKEAGINVADDEKRLNSS----------------------------------------------DTTCGFSIFRGPALQRFATAHMFVIVYGIASCFLAMAFTYFTGTITTMEKRFNIPTKISGLITVGNDISTVFSSAFLSYYASRGHRPRWVALGLIIIAIFCLLMLTPHIFYGPGEEALRLTEEYG-----MSESFGASLNITE--KNDSLCHE------KNSNCL-ERAG-DY------TPIVLFFIAQFIG-GIGCSLFYAPGLSYMDDNSASSKTPAMLSWSSFLRMLGPAMGFSMVSLCLRLYIDP----FKKPLITTNDPRWMGAWWIGWILLTFILTISAVFVGMFPKEMPRAKAR-----------------------RLKADGEE-----------DIPLAGRSFQDMLDSLKRLASNKVYVYNMLASILYLFGYMPYWIFTPKYIEIQYRQSASTSTMATGTWALGFSAAGILISGYVISKYKPSARAMAAWNFVVDYLTVAGMLCYVLVGCDESD-----------RANSLSIVPTGDSCSASCVCEYVYYAPVCSP-ENITFISACHAGCTDKAINELGK-TIYTGCRCMGNVSS-------IISLSNVTSLASQSQ-----------------------------------IAMDGACPVD--CNKQFLIFLAVMCFLKFVGATGRSSNLLLALRCVPSKDKTFSLGFGSMVYSVLAFIPSPIVFGWMLDSYCLVWG-KTCSSKGNCWIYDTKSLRYTMNLVCASLIFLGSFWNIGVWYHAKDMKVFDEDEKTVQAKQSDDIELKEKPNDVVTKKK--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W271-1", "uniprot_id": "Q9W271_DROME", "id": "Q9W271-1", "name": "Solute carrier organic anion transporter family member", "aln": "------------------------------------------------------------------------MTEERGKVDLEKSETLPFIEKPFAISDKERESAPENETEGEDGG------------------------------------KDTYCGFWIFKGPSMQRFATEHMYVILYGLAGCVMTMTFAYFNGTITTLEKRYKIPTKVSGIISVGNDISTMLTAAILGYYAGHRHRPRWMGIGLLTIVAFCLLTSSLHFLYGAGEDALQLTREFG-----QVN---ETLTNQE--RDKKLCQP------TAGGCVQEEVG-LW------VPQVFLFAAQLIS-GVGQALFYTLGIAYMDDNTSKAKTPAMLSMSTFLRMLGPAIGYSLAAVCLRLYIEP----TLEPLIGQEDPRWLGAWWLGWLVLAAITLVSAILLFMFPKQLPSARKR-----------------------RLQLKQDER--------KQSLPLNERSLADMMKTVKKLSKNKVYVYNTMASILYFFGYMVYWIFTPKYIETQYRQSAAMATMATGTVALGFSAAGILISGYVISKYKPSARAMAAWNAIVDFVTVAGILCYVAIGCEGSD-----------RLNTLTTLSAGNSCSASCHCDYVHYAPVCSA-DNITFISACHAGCSERTKDALGR-TIYTGCECLG---------------SSSLNSEPESQ-----------------------------------FAVDGTCPVD--CFNEFLIFLGVMCFLKLVGASSKSTNLLLALRCMPPDEKTFALGLGSMAASLLGFIPSPIFFGWLIDNYCLVWG-KTCSNKGNCWLYDTKSMRYALNLSAAFFIFLGGFLNIAVWYHAKNLKIFDEEESSPKDSLKN-KEVEMKTIDSNPE----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W269-1", "uniprot_id": "Q9W269_DROME", "id": "Q9W269-1", "name": "Solute carrier organic anion transporter family member", "aln": "---------------------------------------------------------------MVQSENPSSLGAELQDLEHGRRESRDESDVESRLLNNGKSYDKEKEAGNQDGEETTPKTGKSKKKKQKSEQDRLMTAEINKLLAESPLEKNVTCGFWIFKGTFYQRFANQTAYVLLYGIVGCIFSMTYAYFNGTITTIEKRFKIPSKNTGIISVGNDISQTLVSAVLAYYAGKGHRPRWIGFGLLTIVFFCILTTAPHFLYGPGEDALALTSEFG-----GMPDENATMEAIEEQRSKTLCRL------NGGGAECEVGEGNF------APQLLLFVAQFIS-GIGGSLYYTLGVSYMDDNTKKSKTPALLSLSYFLRMLGPAIGYALASFCLRLYIAP----QMHPVINNKDPRWLGAWWLGWLVMGGLLSFSGVFLSMFPKELPRAVARRK-----------VEENRRREKERLSVKSTEKERLTAELDQKTTAEAKASFQDMLKTFRRLITNKTYMCNTLSSIFYLVGYTPYWIFTPKYIEVQYRQSAATSSMVTGTVALAFSAVGVLLSGFIISRYKPRARYMAAWNVIVGFLTVAGILAYAFIGCPGNESS------VIVNIHDSSLAGNTTTCNSACSCDYVRYSPVCGE-NNMTYISACHAGCKKLLVNSEGK-KIFYDCSCIPSDDAGNSTSQFKRLTSFDLSNDEVSQNTSVHSQLE---------------------ALANGQAMPGACPVN--CWTQFVAFLAVMCCLKFVGASGRASNFLVSVRCVPEKDKTAAMGFGMTLCSMLAFIPSPIFFGWVFDRVCLVWG-KTCTNKGNCWLYDPLSMRYTLNFTAAVFIAIGAIFDLGVWYYAKDLKIFDEDVKEVEMKIVQHEEEANNEKNTEI-----------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VK84-1", "uniprot_id": "Q9VK84_DROME", "id": "Q9VK84-1", "name": "Solute carrier organic anion transporter family member", "aln": "-------------------------------------------------------------------------------------------MAEVKRRDPNRPPG------------------------------------------------HYLCGMANWHPPWLQKYATTKMFMGVYGLLGTIQAMSYMYFIVTLTTLEKRFKIPSQTTGIILSGNEISQIMLSLILSYIGGQRNRPRWIAWGIVFCGLSCYILVLPHFIYGAGHEVLQFTKEYQDSLLNGTTGSDHSFQNISSVKTERLCGV------DKTEDDCDDLF-SY------VPLVLIFLSQFVL-GVGNTLYYSLGQTYLDDNTKKTNTPLMLAVAMALRMIGPVVGFFFGFISLNTFIDP----TKTPLIDSKDPRWLGAWWLGWVILGTLMCLFSGLIGLFPKQLPKVNASRTNSHLPLALRQTKEELKREENLSLSSRFSSNAALDTIGAAAGANADLPKLKDFPRALMRLLRNKLLIFNILSAVFYILGASGFMTFLTKYMEVQFHKDAQSATIIVGPISIMGMVVGLIGSGMVLSKKKPSVSKVLMWNVIVGGISILGQISYAFLYCPNTFS-----------MTQAGQLNLTSNCNMNCSCEGISYTPVCHEPTDTTFFSACHAGCRGYNATS----KLYEDCSCVVNDPAPKSAAQRLLNLLQPTPEPELDTTTYFDEYLSGVPLLDDNGDFDDQLLSRTRRSTSDSVIRPGICTKN--CNWSFWAFSITSMIVSWFGSSGRVGNVLVNYRAVAHEDKSFAQGLALMMISLLALIPGPIIFGRLIDSTCLVWT-KTCNGNGNCQLYDQTRFRYSLNFLSCLLTFMGLLFDYLVWYYGRNLDIYGDKEAKEEERANRKDQPITPLLAKKSEQE--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VVH9-1", "uniprot_id": "SO74D_DROME", "id": "Q9VVH9-1", "name": "Solute carrier organic anion transporter family member 74D", "aln": "MTKSNGDVEAAAQVQSLGGKPSNGHGQLNGNGYHQNGGRRDSSQAFTPLLSQHNNGTTNGEVTTPPPSTVLYESTPSNNNEWKAPEDLGHLKNGLGNILSSNNNGTGNGHSLSEKYAHEQAPLTGGYKLPPRSSESEESDFDSDLNGGSSAESSSSCGLFGCRPRWARRFASTHVFMVVFLLAYILQGMYMTYFVSVITTIEKLFQIKSKTTGILLSASEMGQICTAMLLTYFAGRGHRPRWIACGMVLFSIAAFSCALPHFIFGEQLMHSSVILQQTQVSPPNNSFSSHWLNASSEQVNPNLCILGGNQTHSGSECNEERQLEQASHSKITVIVLCIFFGSLLSSGIGQTAVATLGIPYIDDNVGSKQSPMYMAVTIGMRILGPASGFIFGSFCTRWYVNFS-----NPGFDATDPRWIGAWWLGPVAIGSLMLLASIAMFSFPKQLRGKQKPPGQT--------------------------------ATPAAPVEPEEKPKLKDFPKTVRRQLSNDILMFRTASCVFHLLPIAGLYTFLPKYLETQFRLATYDANMIAAFCGILVMGIGIVISGLFILKRKPTARGVAAWIAFTALVYSAGMIILMFIGCSMNDFAG----YKPSDGNSPALIEPTCSAALNCTCDKENFAPICAD--GKMYISACHAGCSSSSLRPSDNRTLYSDCACIPDAP----------------------------------------------------------EAVNGYCDNN---CKNFIYFILIFAICVFMHSTSEVGSMLLVMRCTHPKDKAMAMGVIQSAIGLFGNVPCPIIYGAVVDSACLIWK-SVCGKHGACSLYDADTFRQYFLGITAGIMFLAFLMDLVVWRKAHRIDIAPEDPQEGGPASNGRTLEVSESKQPITPAPDTTV----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*: : : :. *:: . :. : : . : :** :. * *.: . : : .: .. : *:* : . * .*::* ::. :. . . : :: : *.* :****:. . . . . . :* : . . :: . : * :* :: : : . * . * .: : : * . * * : *:* . :::.* :** : .* *: * . . : : : . *: . *. :. : *: * :.* *: * * . * *: . . . : : ", "identical_positions": 43, "similar_positions": 109, "identity": "4.57%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100819-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FYB1-1", "uniprot_id": "ARSI_HUMAN", "id": "Q5FYB1-1", "name": "Arylsulfatase I", "aln": "MHTLTGFSLVSLLSFGYLSWDWAKPSFVADGPGEAGEQPSAAPPQPPHIIFILTDDQGYHDVGYHGSDIETPTLDRLAAKGVKLENYYIQPICTPSRSQLLTGRYQIHTGLQHSIIRPQQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRRGFDTFLGSLTGNVDYYTYDNCDGPGVCGFDLHEGENVAWGLSGQYSTMLYAQRASHILASHSPQ-RPLFLYVAFQAVHTPLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDNGGQTFSGGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKRKQRTSRALMHITDWYPTLVGLAGGTTSAADGLDGYDVWPAISEGRASPRTEILHNIDPLYNHAQHGSLEGGFGIWNTAVQAAIRVGEWKLLTGDPGYGDWIPPQTLATFPGSWWNLER-MASVRQAVWLFNISADPYEREDLAGQRPDVVRTLLARLAEYNRTAIPVRYPAENPRAHPDFNGGAWGPWASDEEEEEEE----GRARSFSRGRRKKKCKICKLRSFFRKLNTRLMSQRI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q32KI9-1", "uniprot_id": "ARSI_MOUSE", "id": "Q32KI9-1", "name": "Arylsulfatase I", "aln": "MHALSGFSLVSLLSLGYLSWDWAKPGLVADGPAEAGDQPSVAPPQPPHIIFILTDDQGYHDVGYHGSDIETPTLDRLAAEGVKLENYYIQPICTPSRSQLLTGRYQIHTGLQHSIIRPRQPNCLPLDQVTLPQKLQEAGYSTHMVGKWHLGFYRKECLPTRRGFDTFLGSLTGNVDYYTYDNCDGPGVCGFDLHEGESVAWGLSGQYSTMLYAQRASHILASHNPQ-NPLFLYVAFQAVHTPLQSPREYLYRYRTMGNVARRKYAAMVTCMDEAVRNITWALKRYGFYNNSVIIFSSDNGGQTFSGGSNWPLRGRKGTYWEGGVRGLGFVHSPLLKKKRRTSRALVHITDWYPTLVGLAGGTTSAADGLDGYDVWPAISEGRASPRTEILHNIDPLYNHARHGSLEGGFGIWNTAVQAAIRVGEWKLLTGDPGYGDWIPPQTLASFPGSWWNLER-MASIRQAVWLFNISADPYEREDLAGQRPDVVRTLLARLADYNRTAIPVRYPAANPRAHPDFNGGAWGPWASEEEEEEEEEEEEGRARSFSRGRRKKKCKICKLRSFFRKLNTRLMSHRI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2R8QMU9-1", "uniprot_id": "A0A2R8QMU9_DANRE", "id": "A0A2R8QMU9-1", "name": "", "aln": "-MALLVLLILSLPACASMRTNRED--FEGFRVEEKPEAAAFKPKQPPHIIFILTDDQGFNDIGYHSGEIRSPTLDKLASEGVRLENYYVQPLCTPSRSQLITGRYQIHTGLQHSIIRPRQPNCLPLDVVTLPQRLQEIGYSTHMVGKWHLGFYRKDCLPTRRGFHTYFGSLTGSVDYYTYGSCDGKSLCGFDLHEGESVAWGRAGKYSTHLYTQRVRKILATHDPTSQPLFIFLSLQAVHTPLKPPKEYIYPYRNIGNVPRRKYAAMVSIVDEAVRNITYALRKYGFYRNSVVIFSTDNGAQPLTGGSNWPLRGCKGTYWEGGIRGVGFVHSPLIRHRRRISRDLIHITDWYPTLVGLAGGNVSQHQGLDGFDVWPTISEGKESPRLEILHNIDPLNRRSR-GSLKDGYGLWDTTVQAAIRVGDWKLLTGDPGNGDWVPPHVLTHFPSSWWHLERDIGEKRKSVWLFNVTGDPCERHDLAVHRPDVVRELLARLAFHNRTAIPVRYPPDDTRANPSANGGAWRPWVGEDDEEENWD---GVYYKRGKNRKRKKCRLCKLQSFFKKFNLKIMSKQI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : ::** : . : : . : . * : .: * **************::*:***..:*.:****:**::**:*****:**:********:*****************:******** *****:*** *****************:********.*::*****.******..*** .:*********.**** :*:*** **:**. :***:*.* .***:::::*******:.*:**:* **.:***.********: :********:**::****.***:***:***.*.::********* ********:**:*******:::::* ** *:***************..* :****:****:****: *** ********* .::: ***:.*:*:*:*:********:********* ***:**:.*: **.***:*** :.. *::*****::.** **.*** :****** ****** :**********. :.**:*. ***** **..:::***: * . .:.*::***::***:***:*:* ::**::*", "identical_positions": 369, "similar_positions": 141, "identity": "64.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100819-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UHL1-1", "uniprot_id": "CAMKV_MOUSE", "id": "Q3UHL1-1", "name": "CaM kinase-like vesicle-associated protein", "aln": "----------MPFGCVTLGD-KKNYNQPSEVTDR--YDLGQVIKTEEFCEIFRAKDKTTGKLHTCKKFQK---RDGRKVRKAAKNEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENG---LIKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDYEFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWISGNAASDKNIKDGVCAQIEKNFARAKWKKAVRVTTLMKRLRAPEQSGTAATQSA--SDAATPGAAGGAIAAAAAAAAAGGAASASGASATAATEGGAGCAAKSDDIASADRSATPATDGSATPATDGSVTPATDGSITPATDGSVTPATDRSATPATDGRATPATEESTVPATQSSALPAAKAAATPEPAVAQPDSTALEGATGQAPPSSKGEEATGCAQESQRVETS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63092-1", "uniprot_id": "CAMKV_RAT", "id": "Q63092-1", "name": "CaM kinase-like vesicle-associated protein", "aln": "----------MPFGCVTLGD-KKNYNQPSEVTDR--YDLGQVVKTEEFCEIFRAKDKTTGKLHTCKKFQK---RDGRKVRKAAKNEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENG---LIKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDYEFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWISGNAASDKNIKDGVCAQIEKNFARAKWKKAVRVTTLMKRLRAPEQSGTAAT-----SDAATPGAAGG-----AVAAAAGGAAPASGASATVGTGGDAGCAAKSDDMASADRSATPATDGSATPATDGSVTPATDGSITPATDGSVTPATDRSATPATDGRATPATEESTVPAAQSSAAPAAKAAATPEPAVAQPDSTALEGATGQAPPSSKGEEATGCAQESQRVETS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NCB2-1", "uniprot_id": "CAMKV_HUMAN", "id": "Q8NCB2-1", "name": "CaM kinase-like vesicle-associated protein", "aln": "----------MPFGCVTLGD-KKNYNQPSEVTDR--YDLGQVIKTEEFCEIFRAKDKTTGKLHTCKKFQK---RDGRKVRKAAKNEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENG---LIKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDYEFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWISGNAASDKNIKDGVCAQIEKNFARAKWKKAVRVTTLMKRLRAPEQSSTAAAQSASATDTATPGAAGG-----ATAAAASGATSAP--------EGDAARAAKSDNVAPADRSATPATDGSATPATDGSVTPATDGSITPATDGSVTPATDRSATPATDGRATPATEESTVPTTQSSAMLATKAAATPEPAMAQPDSTAPEGATGQAPPSSKGEEAAGYAQESQREEAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JVK9-1", "uniprot_id": "A0AC58JVK9_DANRE", "id": "A0AC58JVK9-1", "name": "CaM kinase-like vesicle-associated protein", "aln": "---MMRAGAAMPFGCLTLGE-KKDYNSPSEVTDK--YDLGQVVKSEEFCEIFRAKDKNTLKMYTCKKFLK---KDGRKVRKAAKNEILILKMVKHHNILQLVDVFETRKEYFLFLELATGREVFDWILDQGYYSERDTSNVIRQVLEAVAYLHSLRIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENG---LIKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYDETDDDDYDNHDKNLFRKILSGDYEFDSPYWDDISDSAKSLVACLMDVDQDQRLTAQEAINHEWISGNAASDKNIKDGVCAQIEKNFAKAKWKKAVRVTTMMKRLRAPDQS----------------------------------------------------------------------DSGASSPALG-------------ASGGPVTPST------------------------------------TPVPLAATPEASASTRCNGEMLTS---QQRSGDNREE------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P27466-1", "uniprot_id": "KCC1_YEAST", "id": "P27466-1", "name": "Calcium/calmodulin-dependent protein kinase I", "aln": "MDDKVSEKESSPKQTEEDSEGKMAHVQPASYVNKKKYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYP------VKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLEDPWIICTELKTHNLLPGLKEGLDARQKFRNSVERVRLNMKIQKLRDLYLEQTESD---------------------------------------------------------SDFDEGSQANGSVPPLKATDTSQLSKKLSEEEQSKLKSELTSKAFAQLVN----------------------TVLAEKEKFLNINRVCSSDSDLPGSDIKSLDEAKEKPEGKDTKTEE--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: * : .*:. .:: * :*:.: : * : :**:. * : : * : * :..: :* :*: **: ::* **: : * * ::.::::: :**.* *:** **.:* ::*.*: .:: ::*.** *:** .****:** ***:* :: .:* :*::** :** :. *: :*.*: *:****: :: :*:* * *:**** * **.* ..* * :* :: .. : :*. ****.:*: **.:: :::: .:* ** * :.. ** . . :*: *: :: . : : **:. :::** . .*: .* . : * . .:: *. * : :: ", "identical_positions": 101, "similar_positions": 136, "identity": "18.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100819-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5VU97-1", "uniprot_id": "CAHD1_HUMAN", "id": "Q5VU97-1", "name": "VWFA and cache domain-containing protein 1", "aln": "MARQPEEEE----TAVAR----------ARRPPLWLLCLVACWLLGAGAEADFSILDEAQVLASQMRRLAAEELGVVTMQRIFNSFVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTISCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADTVRTCSLDQCYKTFLSPATSETKRKMSTFVSSVKSSDSPTQHAVGFQKAFQLIRSTNNNTKFQANTDMVIIYLSAGITSKDSSEEDKKATLQVINEENSFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGVPDRMALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIIAVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTIMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLIDPKGHAPVEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSLAGDLTNLVHGSHCSKYRLARIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALHQCVNSRCSQRLESGDCFGVLDCEWCMVDSDGKTHLDKPYCAPQKECFGGIVGAKSPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVIERHAHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFHHYRS---HHPTLHHSHHLQAAVTVHTVDAEC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PDJ1-1", "uniprot_id": "CAHD1_MOUSE", "id": "Q6PDJ1-1", "name": "VWFA and cache domain-containing protein 1", "aln": "MAREPEEEETVRPAAVVRRCPRCPGWPGAPRPPLWLLCLVACWILGAVADADFSILDEAQVLASQMRRLAAEELGVVTMQRIFNSLVYTEKISNGESEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCTIPPSMMEFDGNFNTNVSRTVSCDRLSTTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTVFPAHKFRCKGSYEHRSRPIYVSTVRPQSKHIVVILDHGASVTDTQLQIAKDAAQVILSAIDEHDKISVLTVADAVRTCSLDQCYKTYLSPATSETKRKMSTFVSSVKPSDSPTQHAVGFHRAFQLIRSTSNSTRFQANTDMVIIYLSAGITSKDSSEEDKKATLRVINEENGFLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSGKYGIPDRTALPVIKGSMMVLNQLSNLETTVGRFYTNLPNRMIDEAVFSLPFSDEMGDGLIMTVSKPCYFGNLLLGIVGVDVNLAYILEDVTYYQDSLASYTFLIDDKGYTLMHPSLTRPYLLSEPPLHTDIIHYENIPKFELVRQNILSLPLGSQIITVPVNSSLSWHINKLRETGKEAYNVSYAWKMVQDTSFILCIVVIQPEIPVKQLKNLNTVPSSKLLYHRLDLLGQPSACLHFKQLATLESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKFSVRNEVMATSHVTDEWMTQMEMSSLNTYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLISLTGPYLDVGGAGYVVTISHTIHSSSTQLSSGHTVAVMGIDFTLRYFYKVLMDLLPVCNQDGGNKIRCFIMEDRGYLVAHPTLVDPKGHAPLEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRSYKFNTSLVGDLTNLVHGSHCSKYRLTRIPGTNAFVGIVNETCDSLAFCACSMVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCEVHQEPVTYTAIDPGLQDALQQCVNSRCNQRMESGDCFGVLDCEWCVVDSDGKTHLDKSYCAPQKECFGGIVGAKSPYVDDMGAIGDEVITLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLENDRDERDDDSHEDRGIISNTRFIAAVMERHVHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDDDLDLDTPPQTAALLSHKFHHYRP---HHPTLHHSHHLQAAVTVHTVDAEC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F5Q0-1", "uniprot_id": "E7F5Q0_DANRE", "id": "E7F5Q0-1", "name": "VWFA and cache domain-containing protein 1", "aln": "MASRSRTGPRFSFAAWSKHSRPNWNNLEISKWSLVALLVFACCGFCG-ADSEFSILEEAQVLAVQMKKLSTQELGVLTMQRIFNSFVYTEKTSNGETEVQQLAKKIREKFNRYLDVVNRNKQVVEASYTAHLTSPLTAIQDCCSIPPSMMEFDGNFNANVSKTVSCDRLSPTVNSRAFNPGRDLNSVLADNLKSNPGIKWQYFSSEEGIFTLFPAHKFHCKGTFEHRSRPVYVAAVRPQSKHIVVIIDHGASVTETQLQIARDAALVILNSIDEHDKISVLTIADTVRSCSLDQCYKSFLSPATSETKRKMSTFISNIKASDSSTQHAVGFQKAFQLLRNTSNVTRQLTNTDMMIIYLSSGITSRDSSEHEKRATLSAVKEENRHLNNSVMILTYALMNDGVTGLKELAFLRDLAEQNSLKYGVQDRSALPVVKGSMMVLNQLSNLETTVGRFYINLPNRMIDVATFSLPYADQMGDGFIMTVSRPCYFGNLLLGVVGVDVNLAYILEDVTYYQDSLASYTFLIDNKGYTLMHPSLTRPYLMTEAPLHTDIIHYENIPGFPVVRQNILSLPLGSQVIAVPVNSSLSWHMNRLRDPNRDAYNVSYAWKLVQDTSFILCIVYVQPEIPVKQLKNLNTAPSSKLLYHRLDLLGQPSSCLHFKQLATVESPTVMLSAGSFSSPYEHLSQPETKRMVEHYTAYLSDNTRLIANPGLKSSVRNEVMATSHVTDEWMSLMEMSSLNCYIVRRYIATPNGVLRIYPGSLMDKAFDPTRRQWYLHAVANPGLITFTGPYLDVGGAGYVVTISHTIHAPSSQMASGYTVAVMGIDFTLRYFYKVLLDLLPICNQDKGNKIRCFIMEDRGYLVAHPTLIDPKGHAPAEQQHITHKEPLVANDILNHPNFVKKNLCNSFSDRTVQRFYKFNTSIVGDLTNLVHGSHCSKYRLTRIPGTNAFAGIVNETCDALAFCACSTVDRLCLNCHRMEQNECECPCECPLEVNECTGNLTNAENRNPSCDVHQEPLSLTVIEPSLQDTLPQCINTRCSQRFTSSDCFGVLDCEWCMVDSDGKTHLDKPYCALQKECFGGIVGAKSPYVDGMGILDEELASLNMIKSAPVGPVAGGIMGCIMVLVLAVYAYRHQIHRRSHQHMSPLAAQEMSVRMSNLDNERDDRDEDSHEDRGIISNTRFIAAVIERHTHSPERRRRYWGRSGTESDHGYSTMSPQEDSENPPCNNDPLSAGVDVGNHDEDLDLDTPPQTAALLSHKFHPYRHPHMHHPLHLHTHHLQAAVTVHSVDAEC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** ... :* : : .* * :.** : . *:::****:****** **::*:::****:********:***** ****:**********************************************:*************:***:*:******.****************************************:******:***::******:**::***********:*******:******:*** ***.:***********:**:**:********::***************:*.:*.***.*******::****:*.*.* *: :****:*****:****:****.:*:*** .::*** .********************************** ***: ** ****:********************* ******** *.****::*:****:*****:**********:*****************************:***************::*.************* * :*************:*:**********:*:**:..::*********:*********** :**************.*****************:*********:****:******************************************* *****************: ******* ********************************************::*********************:.*:*::**:******************:****:**** *********************:******* ************************************** ******:.*****************:********.********:******* *******************************************:*****:: *.*:*.***:* **:*:**.**: *.***********:***********.*** *****************.** :.:*: :*********************************************************:*:**:**:******************:***.**************************************************:******************* ** *** *:**********:*****", "identical_positions": 1082, "similar_positions": 142, "identity": "83.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100820-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q92585-1", "uniprot_id": "MAML1_HUMAN", "id": "Q92585-1", "name": "Mastermind-like protein 1", "aln": "MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAAT-------APAPAAPAPRLDAADGPEHGRP--------ATHLHDTVKRNLDSATSPQNGDQQNGYGDLFPGHKKTRREAPLG--VAISSNGLPPASPLGQSDKPSGADALQSSGKHSLGLDSLNKKRLADSSLHLNGGSNPSESFPLSLNKELKQEPVEDLPCMITGTVGSISQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDIN-IKTEFSPAAFEQEQ-----LGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPSPNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATPAPAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGPYLQP-SHVNLLSHQPPSNLNQNSANN---QGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALMAYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVP----VQAQATSVGTQPPAVSVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQQFQRHLTRPPPQYQDPTQGSFP-------------QQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMPMGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYG-MASGITQIVAQPPPQATNGHAHIP-----RQTNVGQNTSVSAAYGQNSLGSSGLSQQHN---KGTLNPGLTKPPVPRVSPAMGGQNSSWQHQGMPNLSGQTPGNSN--VSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVGSLLPPVSAQQRTSAP-----APAPPPTAPQQGLPGLSPAG----PELGAFSQSPASQMGGRAGLHCTQAYPVRTAG-QELPFAYSGQPGGSGLSSVAGHTDLIDSLLKNRTSEEWMSDLDDLLGSQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6T264-1", "uniprot_id": "MAML1_MOUSE", "id": "Q6T264-1", "name": "Mastermind-like protein 1", "aln": "MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALHQRCIQAKAKRAGKHRQPPAAATAPVAAPAPASAPAAARLDAADGPEHGRP--------VAHLHDTVKRSLDSAASPQNGDQPNGYGDLFPGHKKTRREAPLG--VSVSANGLPPASPLGQPDKPSGGDTLQTAGKHSLGLDPINKKCLADSGIHLNGGSNSSEPFPLSLSKELKQEPVDDLPCMIAGAGGSVAQSNLMPDLNLNEQEWKELIEELNRSVPDEDMKDLFTEDFEEKKDPEPPGSATQTPLAQDIN-IKTEFSPAAFEQEQ-----LGSPQVRAGSAGQTFLGASSAPVGTDSPSLGSSQTLFHTTSQPGVDNSSPNLMPASAQAQSAQRALTSVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQAAPAPGPGQLATWQQAGPSHSPLDVPYPMEKPASPSGYKQDFTNSKLLMMPGVNKSSPRPGGPYLQP-SHSNLLSHQSPSNLNQNPVNN---QGSVLDYGNTKPLSHYKADCGQGGPGSGQNKPALMAYLPQQLPHLSNEQNSLFLMKPKSGNMPFRSLVPPGQEQNPSSVP----VAAPAASVGTQP-TVSVASTHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQQQLQQQQFLQR-QHLLAEQEKQQFQRHLTRPPPQYQDPTQSTFP-------------QQVGQFTGPSAAVPGMNNLGPSNSSCPRVFPQPGTLMSMGPGHAPVSSLPSSSGQQDRGVAQFTGSQSLPQNSLYG-MASGLAQIVAQPPPQATSTHAHIP-----RQTNVGQNASTSAAYGQNSLGSASLSQQHS---KGTLPPGLTKPQVPRVSAAMGSQNASWQHQGMPNLSSQTSGNSS--VNPFTAAPSFHIQQ-AHLKLAGQQFSQAMPSRPMAPLSSAGAAGPMLPPVSAQQRNSAP-----ASAPPQAAPQQGLPGLSPSG----PELGAFGQSPTSQMSGRPGLHCAQAYPVRTMG-QELPFAYSGQPGSSGLSSVAGHTDLIDSLLKNRTSEEWINELDDLLGSQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IKI2-1", "uniprot_id": "A0A0R4IKI2_DANRE", "id": "A0A0R4IKI2-1", "name": "", "aln": "------MMADFVVPRHSAVMERLRRRIELFRRHHTGCENRYDNTAMERLEMERQQTIALQQRFLQTKAKRSNKHRQPPAAAAASADPVGQRGASGGGGSAEIADGGSGTPGEQSRNSTLIALQETVKRKLESAESPLGRDQVNGFTDGYPPNKKSCVEDAMGGLNGVSNGVVPPLSPLDTKHNVN-TDAMMANGNHRVVGSEHNGASLKDNGAVRGSESDFR-------LKEPKQEPVDDALSCILPQGGANGNNSLFPDLNLNDQDWSEIMEEFNRSVPYEDIQELFSVSFGDRKDPELTSAAAQSLISQDLPNVKTEISPATATSAFEQDSCNGSPQMRPTSSGPPLHTNSPVTAPATSPALPVPQHSQQGSIQSRALPN--HLMPVPPKDLSPAQQLQQLAQQR----------AILHSQQHVVQKPPQQKPPQQQPTKFHQQPSHSTSWPQNAPTQSQMGGTFGLEKPTSPSLYPQDFPNPKTLLMPNKGSPKAGAPAGYMQPGGHANMLSHPAAPTGPLGHPSNPGAQAAMLDFNNTKPLSHYDD----GPPGAPRGPPTTQNHNKPNQAILN-MMRQQQIQKQRAPTMNFRPAHLPHTAQDSGSYPPNTHVPGPSNTMTPQTSSNSIPGHHNNPAYLKQQQIQLMNQQKQFQLQRQIMVEQEKQRQQQEQQLQRHLTRPPPQYQDQQNPQAQQNPFQQQQQQVSQFTSVPPCLAQQHTSNFSEHTISGASQPIGNVNTLSGPAPGTQRMFSQTQGMMGIGVGQNAGPNTGPSTAASQADMSLPPCSNLDVQQVLYGNISMHASHANQQRQPVSTMSAAYRQNVLAAQQQAHLKNQPNAALLKQQQQQLARLPNNMANAMSNNMGSAMPTSMPTSIPGALPVQAQSWQQQPPQQHPALQSGSANGAMPAGFPNSSFHMQSRLTKLPNNTPFPQGGMGNSAAGRTMGGMNPGQMMTNMNQQRTNNPGMPQQLPPPVQQTAQQGQPQAPPQTQQVLPDLGPFSQAQAVPN-RTTGLQCNQAYQLNRAANQQLQFSYNTQSGGS-LSGFPAETDLVDSLLKDQSTQQWMDDIDELLASHQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:*.:**************** ****: ** **: .: ****:***:*:**:** :*:****:.********: . *. . . * * *::****.*:** ** . ** **: * :* :**: * .:* .:* . :** ***. .: . *:: : *:* : . * * *.. .. *: ** *****:* . * *: .:..*:******:*:*.*::**:***** **:::**. .* ::**** ..:*:*: ::**: :***:***: . ****:*. *:* .: *.... : **:* .* : : *. . :***...: .. : * :. : : ** ..:: :* : * : *.: ::* * .*::* :. .: :***:*** * ***.*.* *:**. ..... . . *:** .* *:*** .... . .* *.::**:.********. * **: :. *: : : . :. .. : * :. .* **. * *:..* * * . : :: .*. : *:.. **...**..** : :*:*: *::* **:::: **:* *** . * ::* : : : * * *: . *. . ::*.* .: .:*.*. . .. *:*.*. :* :* *: . .. ..:. .: .:: . *: *. *** :: :: * * :* *: :* :* . :* *:. : *.:: ...: ..:... . :. *: * ***:* : .. .*.:. : . . .***:*. . *.*. ... * : .. : . ***.. * ..* :.*** * .* *:**.*.*: : .**:* *** :. . *:* *:*. *.*.* **.....***:*****::::::*:.::*:**.*: ", "identical_positions": 315, "similar_positions": 341, "identity": "29.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100824-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O75052-1", "uniprot_id": "CAPON_HUMAN", "id": "O75052-1", "name": "Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein", "aln": "MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDLDAVGKEGGSHTGSKVS-HPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKLSGQ-----NAMGSQDSLLEITFRSGALPVLCDP-TTPKPEDLHSPPLG---AGLADFAHPAG--SPLGRRDCLVKLECFRFLPPEDTPPP-AQGEALLGGLELIKFRESGIASEYESNTDESEERDSWSQ--EELPRLLNVLQRQELGDGLDDEIAV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D3A8-1", "uniprot_id": "CAPON_MOUSE", "id": "Q9D3A8-1", "name": "Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein", "aln": "MPSKTKYNLVDDGHDLRIPLHNEDAFQHGISFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDGVKVILKKKK-----KKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSDGSGDPGRQLTGAERVSTAAAEETDIDAVEVPLPGNDILEFSRGVTDLDAVGKDGGSHIDSTVSPHPQEPMLTASPRMLLPSSSSKPPGLGTGTPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKLSGQ-----NTMGSQDSLLEITFRSGALPVLCES-TTPKPEDLHSPLLG---AGLADFAHPAG--SPLGRHDCLVKLECFRFLPPEDTQPMMAQGEPLLGGLELIKFRESGIASEYESNTDESEERDSWSQ--EELPRLLNVLQRQELGDSLDDEIAV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PJM9-1", "uniprot_id": "A0A8M9PJM9_DANRE", "id": "A0A8M9PJM9-1", "name": "Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein", "aln": "MLEKCKYNLVDDSMDQRIPADNEGQFQHGLTFEVKFIGSLDIVRPKSRIEILAAMRRIRYEFKIKNIKKKKVSLIVSVDGVKVVLRKKKK----VKFEYSWDESPVTLAQDPIFRIFYVSHDSQDLKIFSYIARDKKSNVFRCNVFKSKRKSQAMRIVRTVGQAFEVCHKQSLDNADA---WLVKGEEERSKDEAVAAG---SSTERAG------------------------------------DADPETDEKVE------------------EESKSP---LSSPLSVSHQVQLLQRQFQQQEQRSHAASAQVVLLQQQLSVETNARTEAQARVQQLLQQNTELLQHLSLLVKHVQELELRTQPHKN---SPLGSQDSLLEIALRANMPAVSREPKPNPLLSAQRSFPLSNSLVRLDGFHFFTG--ASEQEKKPEQDRDSGRGQDEDQSGGSSPPENQFLSALDTPGFRESGIASGYESNTDESDDRDSWGQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8SXX4-1", "uniprot_id": "CAPON_DROME", "id": "Q8SXX4-1", "name": "Capon-like protein", "aln": "-MPSTPYDLVQDDQDLRVPLHAEQAFFHGITFQAKFVGWEEVPRPNTRAEIVQAMRRIRYECKVQNLKKRKVTIHISVNGVRVVLKKRRR----KKKNWTNDPEDIELLNHPIYRIFYVSHDSSDLKIFSYIARDASTDTFKCSVFKSHKKSQAMRIVRTVGQAFEVCHKFNLHKNSLEPNDERSDISSSELLDVEQISEQQLSEDGERGGGDNETPKK---------------------EHLAITPDLNHTQPQRPNHLDIMPSHSSLRKSNSLLCDVDDKSPGSPSSPRSEITQLKDQLEAQALQTRQALGQLMLVREQLISETNARIEAQARTQQLLQQNRELLEHLASLGAYNEQQTAGLTSANIGMAPQQSQLQMLLQATSNNNNLATINQQISNLGSINQQLTSLSHQLSGLNQQSQHLQNLQQQQQQQQQQQQQQTQAAPTAATPPPAAGGSSPYPSMSALQSISNQLQQQQQQQQQDALSKDLFQVNQELLNRLQALNLNANPGQSQPTPSATAHNSFFYVNPLSCTPATPNNNAGGAGGFNFLTSPAATGTLTPSPLGTMNRNSFAGSSSLNEDIRLSIEQNLNNLEEQLKAAVSNGNLAGLACGGSTSTRDTSRSSSTLDSPSSPRLRSSNNNISPGSSNGNQNHNNNSNSNSSSSRETRFNTVLLRVTDEAGHQRKLSATPSFITRSTSEKVPNRSQMMSQVQRTTWARHTTK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:**:*. * *:* . * * **: *:.*::* :: **::* **: ******** * :*:**:**:: :**:**:*:*:*:: * ::: * . : : :.**:*********.*********** :: *:*.****::******************** .*.: . .. .. . . . : . . . .. :* * :: *: :: * ::: * .*: *:::** *: ** *****.:*** ** ::*:*:: * :: .. : **: : . . .. : .. : *. * .:. . : : : . . .:. .. : . :.: ::: .:* : ", "identical_positions": 121, "similar_positions": 124, "identity": "16.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100901-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14003-1", "uniprot_id": "KCNC3_HUMAN", "id": "Q14003-1", "name": "Voltage-gated potassium channel KCNC3", "aln": "MLSSVCVSSFRGRQGASKQ--QPAPPPQPPESPPPPPLPPQQQQPAQPGPAASPAGPPAPRGPGDRRAEPCPGLPAAAMGRHGGGGGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGADEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDPAGAANAANAAGAHDGGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAGGPPGGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIH--------------------------------ISNKTVTQASP--------------IPGAPPENITNVEVET--------------------------------------------EPFLTYVEGVCVVWFTFEFLMRITFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIP-----RPPQPGSPNYCKPDPPPPPPPHPHHGSGGISPPPPITPPSMGVTVAGAYPAGPHTHPGLLRG------GAGGLGIMGLPPLPAPGEPCPLAQEEVIEINRA--------------------------------------DPRPNGDPAAAALAHEDCPAIDQPAMSPED--KSPITPGSRGRYS--------------------RDRACFLLTDYAPSP----------DGSIRKATG-APPLPPQD-----------------------------------WRKPGPPSFLPDLNANAAAWISP-----------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q01956-1", "uniprot_id": "KCNC3_RAT", "id": "Q01956-1", "name": "Voltage-gated potassium channel KCNC3", "aln": "MLSSVCVWSFSGRQGTRKQHSQPAPTPQPPESSPPPLLPPPQQQCAQPGTAASPAGAPLSCGPGGRRAEPCSGLPAVAMGRHGGGGGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGTDEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDSSGNAN-ANAGGAHDAGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAGGPAGGPGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIH--------------------------------ISNKTVTQASP--------------IPGAPPENITNVEVET--------------------------------------------EPFLTYVEGVCVVWFTFEFLMRVTFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIP-----RPPQPGSPNYCKPDPPPPPPPHPHHGSGGISPPPPITPPSMGVTVAGAYPPGPHTHPGLLRG------GAGGLGIMGLPPLPAPGEPCPLAQEEVIETNRAGNDLGV----------------------------LEEGDPRPNGDPAAAALAHEDCPAIDQPAMSPED--KSPITPGSRGRYS--------------------RDRACFLVTDYAPSP----------DGSIRKATG-APPLPPHAGVSQAPPASCP-----------TSTPTQQPGYPPSGRAPSPPQATPEAPAIFDVWLPPFHRSHQPPGKHQRGGRHPGVSPSPQQRACVGEPPSASHPQSLTLCISVPS---SCHRLRPRETLGFPLSLPPRLATGNGGRECPRDPGLPFPSRHSSPAV-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q63959-1", "uniprot_id": "KCNC3_MOUSE", "id": "Q63959-1", "name": "Voltage-gated potassium channel KCNC3", "aln": "MLSSVCVWSFRGRQGTGKQQPQPVPTPQPPESSPPPLPPPQQQQCSQPGTAASPAGAPLSCGPGGRRAEPCPGLPAVAMGRHGGGGGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGTDEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDSSANAN-ANAGGAHDAGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAGGPAGGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIH--------------------------------ISNKTVTQASP--------------IPGAPPENITNVEVET--------------------------------------------EPFLTYVEGVCVVWFTFEFLMRVTFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIP-----RPPQPGSPNYCKPDPPPPPPPHPHHGSGGISPPPPITPPSMGVNVAGAYPPGPHTHPGLLRG------GAGGLGIMGLPPLPAPGEPCPLAQEEVIETNRA--------------------------------------DPRPNGDPAAAALAHEDCPAIDQPAMSPED--KSPITPGSRGRYS--------------------RDRACFLVTDYAPSP----------DGSIRKGYEKSRSLSSIVGLSG-------------------------------VSLRLAPLATPPGSPRATRRAPPTLPSIL-----------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PG37-1", "uniprot_id": "A0A8M9PG37_DANRE", "id": "A0A8M9PG37-1", "name": "", "aln": "MLSSVCVSSFKGRKGGNKS----------------------SNKACYSADMTCPS--------------------------------ESEKIVINCGGVRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKSDEFFFDRHPSVFSFILNYYRTGKLHCPNDVCGPLFEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFETPEP-------------EVPDDDPALAGDG-------DLKRLCLQEDGRKAG------------WWRVWRPRIWALFEDPYSSKYARYVAFGSLLFILISISTFCMETHEAFNT--------------------------------IYNKTENVT-----------------EGNVTREEIVYEVVT--------------------------------------------DSWLTYVEGVCVVWFTIEVFTRVVFCPDKMEFFKSPLNIIDFVAVLPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPDDPTASAHTNFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIP-----RAPQPGSPNYCKPDALAMATASPQRILG-----------------------------NVLGG------VLGSSGLTG---------DCPLAQEEIIEINRD---------------------------------------SKQNGDAASAALANEDCPTIDQ-VLSPDE--RSPVG-RTQERYQ--------------------QDRACFLLNTREFRPT---------DGNVRKGCVISRVCMLASSYILS-------------------------LFYCLPRPPPPPRSARECVCVCVCCVCCDVTSLIVFSMCFPSLYR------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P17972-1", "uniprot_id": "KCNAW_DROME", "id": "P17972-1", "name": "Potassium voltage-gated channel protein Shaw", "aln": "----MNLINMDSEN----------------------------------------------------------------------------RVVLNVGGIRHETYKATLKKIPATRLSRLTEALAN----YDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLD-----------TEKPSEE--------------ELARKFGFEEDYYKGTIS---------WWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDMRVPIVR------------------------------NITVKTANG--------------SNGWFLDKTQTN-----------------------------------------------AHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFAS--HLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHN-------DFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPRQPRLPGAP--------------------GGVS--GCGTPGSGPHSG-------PMGSGGTG------------------PRRMNNKTKDLVSPKSD----MAFSFD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A8DYR5-1", "uniprot_id": "A8DYR5_DROME", "id": "A8DYR5-1", "name": "", "aln": "---------MDGEN----------------------------------------------------------------------------RIILNVSGIRYETYKATLKKIPATRLSRLTEALAN----YDPVLNEYFFDRHPGVFTQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIE-----------NEKPTEE--------------QIARLFGFEEALSNGELN---------CWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISFCLKTHPGFRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNYTSYSSGNFTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHEAFFYVELVCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFYTD-VMQRMG-----EYTGLLEAFSIVRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAEKLQDNPDN-------QFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEQPRRKREPTAPHRGRTNAIKQTPPTGPGLVAGGVVPVGAGGPGLGGHAVGHSAAGAPMFKDAFGGAKIGTVNVNGVNVIGLHPAQRTTTTMAMAMNEADPTPMSALTYQVPMLQPTPTPAHSHGHAHGHAHGLGPASAAMTSSASLTGSAASAAVATAAAAAPAGPSFISSDYLSVPAVQSLQPRAATTGHDFMLPLQPKLLGPLERKDQHPLQLTAHNLASDTHQLMYSGHAHSQHKVGGGAAVLNVPPTLSMSHTQMPPGIASMGQRTPNLSFRPAHGASSQVATVQQPIPHSHACHASTNCNIKISVASAGLSVGCPDEFRTPKVTLLDDLSDDVNSSTDDCGDCCLVDDSDTYEGTTINNGPSGQENGTEAIGLDDGLLDNDGEDEEDGEGSGVGGDSGDSLGGIYIGPRH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ..: ::::* .*:*:***::**:.:*.***: ***. * *** :*:******.**: :********** * *********** ***:*..:**.*** .* ***::::* :: : : :: :: * : * *: :*::*::*::* ** *: :. *::** :*: :**::** : : : . . * . . : *:* ** .** :*.: *. .*: :*:**.:**** * *.** : :. :. : .:*. . ::**:*:****** **::* :*::**::*: **::**.**:::**:: ****:: .*.: *:.**:*:***:*****:****: *:*: **:**************:******.**.*:** : *: *****:.: :* : * :* . :. : ", "identical_positions": 187, "similar_positions": 143, "identity": "17.43%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100910-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61278-1", "uniprot_id": "SMS_HUMAN", "id": "P61278-1", "name": "Somatostatin", "aln": "MLSCRLQCALAALSIVLALGCVTG-----APSDPRLRQFLQKSLAAAAGKQELAKYFLAELLSEPNQTENDALEPEDLSQAAEQDEMRLELQRSANSNPAMAPRERKAGCKNFFWKTFTSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60041-1", "uniprot_id": "SMS_MOUSE", "id": "P60041-1", "name": "Somatostatin", "aln": "MLSCRLQCALAALCIVLALGGVTG-----APSDPRLRQFLQKSLAAATGKQELAKYFLAELLSEPNQTENDALEPEDLPQAAEQDEMRLELQRSANSNPAMAPRERKAGCKNFFWKTFTSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FFY9-1", "uniprot_id": "E7FFY9_DANRE", "id": "E7FFY9-1", "name": "Somatostatin-2", "aln": "MRLCELQCYLALLGLSLVLCGRSANSQLEPEMDFRHHRLLQRARAIGQA-QEWTKKDVEELLSLLSMPEMQMRES-DLSTTDENEDLRVELERSAESSNHIPARERKAGCKNFYWKGFTSC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *.*** ** * : *.* :. . * * :::**:: * . . ** :* : **** . .* : *. **. : *::::*:**:***:*. :..**********:** ****", "identical_positions": 50, "similar_positions": 33, "identity": "41.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100910-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GGV9-1", "uniprot_id": "A0A8I6GGV9_RAT", "id": "A0A8I6GGV9-1", "name": "", "aln": "--------------------------------------------------MEISNMNREDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEMK--------------------------DYIGDRSIPKLVAIPKPAVPTTTDEKANPNFFEQRH----------------------GGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRSSAGGS-GASGSGQRHDRDSY------------------SSSRKKGQHGSEHSKSRSSSPGKPQAVSSLSSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSR------------------------VPFSSGQHSSQSFPP----------------------SLMSKSSSMLQKPTAYVRP----------------------------------------MDGQESVEPKLSSEHYSSQSHGSNMTELKPSSKAHLTKLKIP-------------------SRPLDASVSGDVSCVDEILKEMTHSWPPPLT-------------------------------------AIHTPCKTEP-----SKFPFP-TKESQQSNFGSGEQKRYSTSAKTSNGHQSK-------SMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNS--------------------------RDDSSSHSGSESSSGSDSESESS-----------------------------SSDSEANEPS-----------------QSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQA--YKKEGREQGTASNYTDPGGAKEASSATPGRDSK----------TIQKGSESGRGR-QKSPAQSDSTTQ-------------------RRTVGKKQPKKTEKS-AAEEPRGG------------------LKIESETPVDMATSMPSSRHKAATKGSRKPNIKKESK-SSPRPTAEKKKYKSASKSSQKSREIIETDSSSSDS-------------------DERESLPPSSQ--------------------------------------TPKYPESNRTPVKPSSAEEDDSFFRQRMFSPMEEKELLSPLSDPDDRYPLIVKIDLNLLTR--------------------------------------------------IPGKPYKETEPPKGEKKNVPEKHSREVQKQASEKASNKG-KRKHKNDDDNRASESKKPKTEDKNSSAHKPSSSKESSKQSSTKEKDLLPSPAGPVPSKDSKTEHGSRK-----RTVSQSSSLKSSSTSNKENSGSSK--STSSTAKQKKTEGKVSSSSKEAKEKAPNSSSNCPPSTPTPDSSKPRRTKLAFDDRNYSAD-----HYLQEAKKLKHNADALS--DRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSDTVELIKYT-MKLKNYLAPDAT----AADKRLTVLCLRCQSLLYLRLFKLKKENALKYSKTLTEHLKNSYSNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGSYSSGGSSASASGSSVTIPQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKE--QKEFFAELDKVMGPLIFNASIMTDLARYTRQGLHWLRQDAKLIS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ESC8-1", "uniprot_id": "AFF4_MOUSE", "id": "Q9ESC8-1", "name": "AF4/FMR2 family member 4", "aln": "-------------------------------------------------------MNREDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEMK--------------------------DYIGDRSIPKLVAIPKPAVPTTTDEKANPNFFEQRH----------------------GGSHQSSKWTPVGPAPSTSQSQKRSSALQSGHSSQRSGAGGS-GASSSGQRHDRDSY------------------SSSRKKGQHGSEHSKSRSSSPGKPQAVSSLSSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSR------------------------GPFSSGQHSSQSFPP----------------------SLMSKSSSMLQKPTAYVRP----------------------------------------MDGQESVEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIP-------------------SRPLDASVSGDVSCVDEILKEMTHSWPPPLT-------------------------------------AIHTPCKTEP-----SKFPFP-TKESQQSNFGPGEQKRYST-AKTSNGHQSK-------SMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNS--------------------------RDDSSSHSGSESSSGSDSESESS-----------------------------SSDSEANEPS-----------------QSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQA--YKKEGREQGTASNYTDPGGTKETSSATPGRDSK----------TIQKGSESGRGR-QKSPAQSDSTTQ-------------------RRTVGKKQPKKPEKS-AAEEPRGG------------------LKIESETPVDMAASMPSSRHKAATKGSRKPNIKKESK-SSPRPTAEKKKYKSASKPSQKSREIIETDTSSSDS-------------------DGSESLPPSSQ--------------------------------------TPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTR--------------------------------------------------IPGKPYKETEPPKGEKKNVPEKHSREVQKQASEKASNKG-KRKHKNDDDTRASESKKPKTEDKNSSGHKPSSSRESSKQSSTKEKDLLPSPAGPILSKDSKTEHGSRK-----RTVSQSSSLKSSGTSSKENSGSSSKSSSSSTAKQKKTEGKGPSSSKEAKEKAPNSSSNCPPSTPTSESSKPRRTKLAFDDRNYSAD-----HYLQEAKKLKHNADALS--DRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSDTVELIKYT-MKLKNYLAPDAT----AADKRLTVLCLRCQSLLYLRLFKLKKENALKYSKTLTEHLKNSYSNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGSYSSGGSSASASGSSVTIPQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKE--QKEFFAELDKVMGPLIFNASIMTDLARYTRQGLHWLRQDAKLIS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHB7-1", "uniprot_id": "AFF4_HUMAN", "id": "Q9UHB7-1", "name": "AF4/FMR2 family member 4", "aln": "-------------------------------------------------------MNREDRNVLRMKERERRNQEIQQGEDAFPPSSPLFAEPYKVTSKEDKLSSRIQSMLGNYDEMK--------------------------DFIGDRSIPKLVAIPKPTVPPSADEKSNPNFFEQRH----------------------GGSHQSSKWTPVGPAPSTSQSQKRSSGLQSGHSSQRTSAGSSSGTNSSGQRHDRESYN--------------NSGSSSRKKGQHGSEHSKSRSSSPGKPQAVSSLNSSHSRSHGNDHHSKEHQRSKSPRDPDANWDSPSR------------------------VPFSSGQHSTQSFPP----------------------SLMSKSNSMLQKPTAYVRP----------------------------------------MDGQESMEPKLSSEHYSSQSHGNSMTELKPSSKAHLTKLKIP-------------------SQPLDASASGDVSCVDEILKEMTHSWPPPLT-------------------------------------AIHTPCKTEP-----SKFPFP-TKESQQSNFGTGEQKRYNP-SKTSNGHQSK-------SMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNS--------------------------RDDSSSHSGSESSSGSDSESESS-----------------------------SSDSEANEPS-----------------QSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQG--YKKEGREQGTGNSYTDTSGPKETSSATPGRDSK----------TIQKGSESGRGR-QKSPAQSDSTTQ-------------------RRTVGKKQPKKAEKA-AAEEPRGG------------------LKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESK-SSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDS-------------------DESESLPPSSQ--------------------------------------TPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTR--------------------------------------------------IPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKG-KRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRK-----RTISQSSSLKSSSNSNKETSGSSK--NSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRNYSAD-----HYLQEAKKLKHNADALS--DRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSETVDLIKYT-MKLKNYLAPDAT----AADKRLTVLCLRCESLLYLRLFKLKKENALKYSKTLTEHLKNSYNNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGNYSSGASSASASGSSVTIPQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKE--QKEFFAELDKVMGPLIFNASIMTDLVRYTRQGLHWLRQDAKLIS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BL85-1", "uniprot_id": "A0A8M2BL85_DANRE", "id": "A0A8M2BL85-1", "name": "", "aln": "------------------------------------------------MASQSGNMNREDRNVLRMKERERRNQEIQQGGEAFPANSPLFPEPIKVA-KEDKLSSRIQSMLGNYDEMK--------------------------ETIGEPPMSKLISKAS----SSSSEDKSGQYGDQRG----------------------GSQTQSSKWTPVGPASGGGNS---SSSSQKRSTVQSVSQKSS----SSGQRHERDYS-------------------GSKKSSKHSNEHKSHSSSSPAK------VSSNHSR-----------RVPKSPRDREANWDSPSIP-----------------------HSFPSG-HPNQTFPP----------------------SLIK-SSSMPQKPTAYVRP----------------------------------------MDGQETTEAKTSSDSYSGQSHSSTVGEMKPNGKGPLPKLKIP-------------------TQPPEA---GDASCVDEILKEMTQVWPPPLT-------------------------------------AIHTPCKTEPP----SKFPFSNAKDAQHQSVG--AQKKFSG-KSASTSHPSKPCDSEQSNMLHDDLKLSSSEDSDGEQDPAKNTPQNNSTSNNS---NNSEGAE----------------------------REDTSSHSGSESSSGSDSESESS-----------------------------STDSETTEPP-----------------RAATPEREQPTANKWLLDNWLNKVN--KLSPASPVENSSSSTPGTKYKKEGRDTSSSRSYSGQ-GSKEAATS-AGRELR----------PNQKSSESWRGRSQKSPAQSEGTSQS-----------------GRRVVGKKQPKKPEKPPVVEEPKGG------------------LKVETEP----SPEIPSHRARAPNKGLRKPNIKKEPKTSSPRPPPDKRKTKAAKVPS-KSREFIESDSSTSDS-------------------EGNESDPLPSQ--------------------------------------TPKDYSEN--PLVP-----------------------LSPIYDPPR---LLVQINLSLLTR--------------------------------------------------VPGQLYNETEV-KVERGSPAEGKS--NQKQPGEKISKEGRKRKHKNEDDGVKPESKKSKLDEKSS---RKSSSNDSSKRAQEKEKESAPSPS-ITLQRTPKSEQQGRK-----RTLSQSS----STVPSKDKS--------SSSSRHRRGDDK--PQRREPKEKS--SKSENPVSVPPLSEGSKSRSKLLFEDRVHSAD-----HYLQEAKKLKHNADALVRMDRFEKAVYYLDAVVSFIECGNALEKNAQEAKSPFPMYAETVELIKYT-MKLKSYMAPDAT----SQDKRLAVLCLRCQALLYLRLFKLRKESALKYSKTLTEHLKNSLSNTQAPSPGVANKSAGMPSPVSPKLSPGSAGSYSSSSSSQSAS-SSVTIPQRIHQMAASYVQVTSNFLYATEVWDQAEQLAKE--QREFFTELDKAMGPLIFNTSSMTDLVRFTRQGLHWLRLDAKLIQ----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQI9-1", "uniprot_id": "AFFL_DROME", "id": "Q9VQI9-1", "name": "AF4/FMR2 family member lilli", "aln": "MAQQQQQQMQQQQQHHTSSINNNNSSSIVLLQQQQPQQQQQQLDQLQQYNNNLYSQNYNMEEYERRKRREREKIERQQGIQIDDRETSLFGEPRRLTEGDAEITAALGEFFEAREYINNQTVGISRSAPGAGNPRLQPNLAPQAKSLGHSPSSASSAAGPTAASATTSLPGQQQHYQQQQRPPTYVKQADNKPPYNGRGGYPGQPMKNDIPSSSGMAPPRGPPRTSSSNSNSSSVTNNASSGGVPASTPLGPPLSTQMPNGREKSFLGPPAPALHNGTGGRFVPPAASKRPGVGQQPPPPEKDVNKIISDIANIFTVQPLTLIAATPHAPTRENYNLLAPNRQKYAMDIPSSPPSAEPSSLMTPLFAPITSPIAPLVTTPPQASQMPLGGATSGTILAGEALAPLHQLPPTMPKAASGVTSPGPVKPLKTEKNHSLEKQDSCLENDLELSESEDEQRKKEGRSGGNSSNSSESDSSESGSESSSKNDLQHHPNHQQHHHQLQQQQQQQQATMQQQQVLQQQHRSQPLTSNGAQNKKFRHEIIARGSNTITGLLSSSGFGSGGNVGPAGVNSNAVVGTGSGSGGTLSSGGSSSNKTPSPTESNKWNLSRFFHKPANQTNSESVSPGNVSMKVPGILPGGAQIIPESIDVTTAIVKNEKNDMAMEEGEEEDDDEEQQLRYGGGLSVTPVAVKKEAIDAVSEMALGAIPKTQIKRESAETLLSARLSDSGTSASGSSSSSSSSSDSAMGGEVVPMPGPGETLQLPGVPAAITTVMRVQPTQSQKAPPSNSVTLTPILPLPTSPKQRQKKPRKKKAITSAPILDSSDDDEPPPKHPGLDHTAVSVQTQPATDTVKKGRGRPRKQQQSGGSGNLSSASAGSSSQTKGPTLTAAKKPLAKTPLAMSRARKREHSSQSSSNGNTPTKKVATPQLVAAPLKPTSNTAGSSSSDEDSSSSAESSSKSSSSSSSSDDTETQNTNCRIVKLNKTGAVQKKALLGSGSSSPSSSGSEAEDQTTRSQVGSGQALAQQLPPYKQLPISQHSQHLSSSDCSSSSGGCTAVCSSSSGEEDEGRREKERERKPKSDKNKINTLTRIFNPKEGGAKKQGQVVIVDLQEEQQQGKLDAAAQPSAPQAPPAAPAAIMAKPRMTPTQQQQLGAGLASPARTTTPHLTSLICKIDLSKLSRERIMRLKKLTPAQQNGHLTPKDQATNAVHVPNGYAGDTNPAAKVKHEHPVKPEPELDAGYEAKFKPGNVKQEFQLKQERDRDRERERERERERERDREREQPPGRRRKRSSSSSSSPYKEKKRKKEKADQLQMGKELLPVPVLLPSNNHERMPNHDRLSYDKLQLLHEDAAAVIGDVSAPNGSPTKKLLAMSPLPPPPTVTVAPATCNEAVQTTPPSATATSAIAPPVPATRLIYRSYFDRDVEHPSDDPRKNNQFLQEAINRKHAADLER--DSFNQVTLYLEAVVYFLLTADAMERCSSE-QATNTMYKDTLSLIKFISTKFRPYQQQSTTNIQHETHNKVAILSLRCQSLISLKLYKLRRKDCRAIINSLTDFFRVGRGDIANGN---------TPSSISPSNSVGSQG-------SGSNTPPGRIVPPDIHNMLCKQNEFLSYLNSAHELWDQADRLVRTGNHIDFIRELDHENGPLTLHS-TMHEVFRYVQAGLKTLRDAVSHPTHQSQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : .: * *.***.: * *** : .:.** ** ::: : :::: : .:: : :: . :*. . . : .::. . :. :*: * :.. :. * *. . . ** :. : . . * . : ..: ..:: ...* : *. :. .::* : * :*. .:.* . : ** .* . . :* : .:. . * .*:.: ..: .*. ..:* ... : :*. : :*: ::* : : . .**: . :: . *: : :**. **. *:* . ::::: .... . .. .: ::::: : : *:.: *:* : : . :.*. : :. :* ***.***.*.*:* . .::*: *. : .*. : . :. **. :. * . . . . : . *:** . :. * .:::: .. : : :. *.* :: .:**... : ...*.....: ... . ...:.. :*::. . : * ....* . : ....: .* :. .:: * :*:.: .:* *:*.. . * * ..: :. . * . .. . *: :*:*. *:* * . * : . : ::: ..: ..: :.:.:: : . :: : ....* : .. .... *: * * .. : : .* : : :.: . . : * *. . . . : .. :.: . : * *: : : . * * ::**** : ** ** * *::.. **:*** *: .:*:*: :.* ::. .** :*:.***: *:: * .:* .:::::*.***::*: *:*:**:::.. ::**:.:: . .: . **.:**. * *. * * * : .. :* **:* .. :. * : * *:****::* : : :*: ***: *** ::: * :: *:.: **: ** .. ", "identical_positions": 180, "similar_positions": 432, "identity": "10.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100913-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q70E20-1", "uniprot_id": "SNED1_MOUSE", "id": "Q70E20-1", "name": "Sushi, nidogen and EGF-like domain-containing protein 1", "aln": "MRLGAAWALLLAAALGLGTRGVRAAVALADFYPFGTKRGDTVTPKQDDGGSGLQPLSVPFPFFGAEHSGLYVNNNGIISFLKEVSQFTPVAFPIAKDRCVVAAFWADVDNRRAGDVYYREATDPAMLNRATEDIRRYFPELPDFSATWVFVATWYRVTFFGGSSSSPVNTFQTVLITDGRFSFTIFNYESILWTTGTHASSGGDTDGLGGIAAQAGFNAGDGHRYFNIPGSRTADMAEVETTTNVGVPGRWAFRIDDAQVRVGGCGHTTSVCLVLRPCLNGGKCIDDCVTGNPSYTCSCLAGFTGRRCHLDVNECASHPCQNGGTCTHGVNSFSCQCPAGFKGPTCESAQSPCDNKVCQNGGQCQAESSSAVCVCQAGYTGATCETDVDECSSDPCQNGGSCVDLVGNYSCICVEPFEGPQCETGSYLVPSP-----CLSNPCQNGGTCVDADEG-YVCECPEGFMGLDCRERILNDCDCRNGGRCLGANTTLCQCPPGFFGLLCEFEVTATPCNMNTQCPDGGYCMEYGGSYLCVCHTDHNISHS-------LPSPCDSDPCFNGGSCDAHEDSYTCECPRGFHGRHCEKARPHLCSSGPCRNGGTCKEMGDEYRCTCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCMNGGTCEDLGTDFSCYCQPGYTGHRCQAEVDCGHPEEVEHATMRFNGTHVGSVALYTCEPGFSLSALSHIRVCQPQGVWSQPPQCIEVDECRSQPCLHGGSCQDLIADYQCLCSPGYEGVHCELETDECQAQPCRNGGSCRDLPRAFICQCPEGFVGIHCETEVDACASSPCQHGGRCEDGGGAYLCVCPEGFFGYNCETVSDPCFSSPCGSRGYCLASNG-SHSCTCKVGYTGKDCTKELLPPTALRVERVEESGVSISWSPPEGTTARQVLDGYAVTYASSDGSSRRTDFVDRSRSSHQLRALAAGRAYNISVFSVKRNTNNKNDISRPAALLTRTRPRPIEDFEVTNISANAISVQWALHRIQHATVSRVRVSILYPEASAVQSTEVDRSVDRLTFGDLLPGRRYTVRLTTLSGPGGAEYPTESLASAPLNVWTRPLPPANLTASRVTATSAHMIWDTPAPGISLEAYVINVTTSQSTKSRYIPNGKLVSYTVRDLMPGRRYQLSVTAVQSTEQGQLHSEPAHLYIITSPRDGTDRRWHHGGHHSRMLRNRPAPVRLPELRLLNDHSAPETPTQSSRFSELVDGRGRVSARFGGLPSRAVTVRSQPTTPVPLKN-TEAPEQVHLALQLPKNSSKDTESTPGSCSEDACQNGGTCVPGADAHSCDCRPGFKGRHCELACEKVPRPCTRLFSETKSFPVWEGDICHHVYKKVYKVHQDVCFKERCQSTSLRKP--KQETK-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TER0-1", "uniprot_id": "SNED1_HUMAN", "id": "Q8TER0-1", "name": "Sushi, nidogen and EGF-like domain-containing protein 1", "aln": "MRHGVAWALLVAAALGLGARGVRGAVALADFYPFGAERGDAVTPKQDDGGSGLRPLSVPFPFFGAEHSGLYVNNNGIISFLKEVSQFTPVAFPIAKDRCVVAAFWADVDNRRAGDVYYREATDPAMLRRATEDVRHYFPELLDFNATWVFVATWYRVTFFGGSSSSPVNTFQTVLITDGKLSFTIFNYESIVWTTGTHASSGGNATGLGGIAAQAGFNAGDGQRYFSIPGSRTADMAEVETTTNVGVPGRWAFRIDDAQVRVGGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDA-----CLSAPCHNGGTCVDADQG-YVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHS-------LPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNG-SHSCTCKVGYTGEDCAKELFPPTALKMERVEESGVSISWNPPNGPAARQMLDGYAVTYVSSDGSYRRTDFVDRTRSSHQLQALAAGRAYNISVFSVKRNSNNKNDISRPAVLLARTRPRPVEGFEVTNVTASTISVQWALHRIRHATVSGVRVSIRHPEALRDQATDVDRSVDRFTFRALLPGKRYTIQLTTLSGLRGEEHPTESLATAPTHVWTRPLPPANLTAARVTATSAHVVWDAPTPGSLLEAYVINVTTSQSTKSRYVPNGKLASYTVRDLLPGRRYQLSVIAVQSTELGPQHSEPAHLYIITSPRDGADRRWHQGGHHPRVLKNRPPPARLPELRLLNDHSAPETPTQPPRFSELVDGRGRVSARFGGSPSKAATVRSQPTASAQLENMEEAPKRVSLALQLPEHGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVCHHVYKRVYRVHQDICFKESCESTSLKKTPNRKQSKSQTLEKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5H9-1", "uniprot_id": "A0ACD6B5H9_DANRE", "id": "A0ACD6B5H9-1", "name": "", "aln": "MGR-LRRPVLSMCTLLILLHGVEPAVPLEEFYPFGLDEGDSQTIEQDDGGSGLVAISVAFPFFGERHTGLYVNNNGLVSFLREVSQFTPVAFPIAGDRRVVAPFWADVDNRRAGKVFYRESKDPAILRRATADTNRYFPEFPTFVTTWVLIATWHQVTFFGGSSITPVNTFQVVLITDGELSFTIFQYHNITWTTGMHATSGGDLAGLGGIAAQAGFNAGDGKRYFNIPGSRTDDIVEIETTTNVGYPGRWVFRIDDSHVQVGGCNDSASVCANLRPCRNGGRCIDDCITGNPSFTCSCLAGFTGRRCQIEVDECSSYPCQNGGTCVDKINHFICLCPVGFIGATCETDIDECQETPCLNGAQCIQGVGNFTCICQAGYTGFLCESDINECMSMPCLNGGVCEDLVNNYTCTCTANFTGSACETELVVADAANQTESCVGEICNKHQICEYTNSGNYSCTCMPGYYGDNCEE----ECPCQNGGICVDVNGT-CDCPTGFTGLYCQFEVTQTPCSNNRPCPDGGPCLEYGGTYLCTCQTGAEFDHKDFYPYVQPQSACDSSPCQNGGYCYERDGDYICECKHGYRGKHCERVRLSICASSPCRNGGSCKEEADSYHCVCPYRFTGKHCEVGKPDPCASSPCRNGGTCFHYIGKYKCECSPSFMGRHCEINRG---SNPALEG--------------------------LDCGPPVKAKHAEVQYSSTTPGSMALYSCHPGYTPLTRATQIICSSQGSWSQPPVCEEINECLSQPCMNGGTCRDRVASYLCECEEGFTGQRCQTDMDECLSEPCKHGSTCEDQPGSYFCHCQEGYAGQDCEMEQDGCEPNPCLNGGICRGYRRNHLCVCKEGYIGDRCQTLENPCVLQPCGNRGVCRSDRRENYSCACRVGHTGRDCERDLLPPSGLNVLRVEENEVELRWDQSD--VTQNLISGFAVAFAPVGRVPRKTDFLEKKHSTYVLQGLNPGQLYNISTYSVN-----SIDKSQPAFALIRTRPRQVDQLEVVNVSSSQVWLRWLVHVGRHAAISQVRVSLVPADGSGSRTAVLNSSVTDYTFSTLLPGQMYTVDVVTQSGLRPEDLPSTSKSAGPLHFWTRPLPPQNLSISHITTTSALVTWDH-HPRSLPDGFVVNITRGLNTRSRYLPEGSLGTYTLRDLIPGQHYRLTLTAVRKTGQDSIHSVPQHLAFATLPVRSTSR-----GDRPQGGQDYQMGQTLTQVQDGGTDENTELLEEPLRYTELIDGRGRITAKFTKLPHKTIRHRIKPDPPIKLERMEETTNKISLALEIPEEASKSKSESSQDCRTQPCQNGGTCAQINESFSCNCPSGFKGRRCELYCQRVSHPCTRLYSETKSVPVWEDGVCHYLYKRTYKVQQDVCFREICEPLLPKKTPHRRTQKQQ-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .:* .:* : :**. **.* :***** ..**: * :******** .:**.***** .*:********::***:************* ** ***.***********.*:***:.***:*.*** * .:****: * :***::***::******** :******.******.:*****:*..* **** **:***: ****************:***.****** *:.*:******* ****.*****::*:****..::*** **** ***:*****:*****:*****:*******:::*:**:* ********.. :* * * **.** *.***: . *: . * :*.** .. .*:******* ** *:::* . ** *** * ***.**:* *. * * *** . . *:. *:: * ::.* * * * *: * :*.* :* *:*** *:..* * *:** ** ** *:**:* **. * ***** *:*:**:***.*:*. : .*. *.***.** *** * ::..* *** :*::*:***:.* :*:*.******:*** ...*:* *******:***:****.***.**:**************:*.*.* ****** . .*.::* :*** * :.:** :::..* *::***:*. *:: : : :*..:* **:** * *::** ****::**:*:* :*.* * *. *: * :*: : *** :.**::*.:*.: * ::.*:* *:.* .** * *.* ..** :** *.. :**** *.::* .*:*:.:**. .***.** * :.. .:**:*:**:**.** ::*:**:.*.: ****. *.: *. .: .:::::.*:**::.. . *:***:::.:*:: *:.* .*: ****.:**: . * *:** * ***** :: :**.*:::. : ::* :* :**::* ****: .:. ::: :: ** ** ****: **: :.* ** : *: * ::.* :.******* **: :::*:*** : ** * :.:*:*:* . .*:***:*:*.* :**:***:**::*:*:: **:.* . ** * ** : * * .:.* *.:.: :: *.::: . .. .* :. *::**:*****::*:* * :: * :* .. *:. *:.::: ***::*:..**. . . .* :.*******. ::.**:* .*****:*** * :*.:*****:****:.****..:**::**:.*:*:**:**:* *:. :*. :: * ", "identical_positions": 662, "similar_positions": 414, "identity": "46.39%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100913-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHA2-1", "uniprot_id": "D3ZHA2_RAT", "id": "D3ZHA2-1", "name": "", "aln": "MVRNVDDLDFHLPSHAQDMLEGLQRLRSLPKLADVTLLVGDQELPCHRSLLALNSPYFHAMFAGDFAESFSARVELRDVEPAAVGQLVDFVYTGRLTITQSNVEALTRSASRLHFPTVQKVCGRYLQQQLDATNCLGICEFGEQQGLLGVAAKAWAFLRENFEAVAQEDEFLQLPRDRLATCLASDLLQVQPEQSRLEALLRWVRHDPQDRAAYLPELLNLVHLDALPRPCVQQLLATEPLIQESEACQEALS-----------QGHSAE-PPGLPQKMQEVLVVVGGRALEEDEEGGEEPSP------HTGNFAFYNTKARQWMALPDFPDYHKWGFSLATLNSDVYVTGGSRGTKTDTWSTTQAWCFPLKEAVWKPVAPMLKARTNHASTALNGEIYAIGGTALDAVEVERYDPYTDSWAPVRPALKYVSNFSAASCQGRLYLVGSSACKYNMLALQCYSPVTDVWSVIASPFLPKYLSSPRCAALNGALYLIGDNTKKVYVYDPGANLWQKVQSQHSLHENGALVPLGDLLYVTGGRWQGMDGDYHVEMEAYDTVRDAWARHGSLPRLWLYHGASTIFLDISKWTQPFSPTAPREH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C3F7-1", "uniprot_id": "KLH30_MOUSE", "id": "Q8C3F7-1", "name": "Kelch-like protein 30", "aln": "MVRNLDDLDFHLPSHAQDMLEGLQRLRSLPKLADVTLLVGDQELPCHRSLLALNSPYFHAMFAGDFTESFLARVELRDVEPAMVGQLVDFVYTGRLTITQANVEALTRSASRLNFPTVQKVCGRYLQQQLDATNCLGICEFGEQQGLLGVAAKAWAFLRENFEAVAQEDEFLQLARDRLATCLASDLLQVQPEQSRLEALLRWVRHDPQDRAAHLPELLSLVHLDAVPRPCVQQLLATEPLIQESEACQEALS-----------QGHSEE-LPGLPQKMQEVLVVVGGRALEEDEDGGEEPSH------HTGNFAFYNTKARQWMALPDFPDYHKWGFSLAALNSDVYVTGGSRGTKTDTWSTTQAWCFPLKEAIWKPVAPMLKARTNHASTALNGEIYAIGGTALDAVEVERYDPYTDSWAPVGPAPKYVSNFSAAGCQGRLYLVGSSACKYNMLALQCYSPVTDAWSVIASPFLPKYLSSPRCAALNGALYLIGDNTKKVYVYDPGANLWQKVQSQHSLHENGALVPLGDLLYVTGGRWQGMDGDYHVEMEAYDTVRDAWARHGSLPRLWLYHGASTIFLDVSKWTQPFIPTAPQEH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q0D2K2-1", "uniprot_id": "KLH30_HUMAN", "id": "Q0D2K2-1", "name": "Kelch-like protein 30", "aln": "MVRNVDDLDFHLPSHAQDMLDGLQRLRSQPKLADVTLLVGGRELPCHRGLLALSSPYFHAMFAGDFAESFSARVELRDVEPAVVGQLVDFVYTGRLTITQGNVEALTRTAARLHFPSVQKVCGRYLQQQLDAANCLGICEFGEQQGLLGVAAKAWAFLRENFEAVAREDEFLQLPRERLVTCLAGDLLQVQPEQSRLEALMRWVRHDPQARAAHLPELLSLVHLDAVPRPCVQQLLASEPLIQESEACRAALS-----------QGHDGA-PLALQQKLEEVLVVVGGQALEE-EEAGEEPTP------GLGNFAFYNSKAKRWMALPDFPDYHKWGFSLAALNNNIYVTGGSRGTKTDTWSTTQAWCFPLKEASWKPVAPMLKPRTNHASAALNGEIYVIGGTTLDVVEVESYDPYTDSWTPVSPALKYVSNFSAAGCRGRLYLVGSSACKYNALALQCYNPVTDAWSVIASPFLPKYLSSPRCAALHGELYLIGDNTKKVYVYDPGANLWQKVQSQHSLHENGALVPLGDALYVTGGRWQGMEGDYHVEMEAYDTVRDTWTRHGALPRLWLYHGASTVFLDVSKWTQPSGPT--QEH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B729-1", "uniprot_id": "A0ACD6B729_DANRE", "id": "A0ACD6B729-1", "name": "", "aln": "MVCNVDDLDFCLSSHPGSILEGLRSLCSQPKFVDVTLSAGGRDFPCHRGILALCSHYFHSMFSGDFIESIAARVELHDVDPDVLSSLLDFAYTGKLTINKNNVEGLICTSSQLQFHTVRSVCCRYLQHQIDATNCLGILEFGEIHGCPEVVAKAWSFLLENFEAVKQHEEFLQLEKDRLVACLKDEDLHLRDDRSCAEAVVSWVRHSKDSRICDLRELLSLAKLSLLSESYLTENLLKEPLVQNSLESRELVERICREKRQLTGDGKTEQRATQDAFNQQEVLFVMGGRSLDDSDDEDEDEDENRDGRLHPRNCGFYNPKLGQWFQLPDFPNYNKWGYSVISLNNNVYVTGGSRGSQSNTWSTTETWKYITREGKWVTVAPMLRPRTNHSSATLNGEIYVIGGTTTD--FVERYDPFSNCWTLTSPALKYVTNFTATPCEGKLYLIGSCAVKYNALTMQCYNPVIDSWCIIGSPFIPKYLSSPCSVSMDGVIYLIGDNTKKVYSYDPDSNVWEKIQFLNMLHENGDLVVLGRYLFVTGGHWKGMEGDYGVEVEMYNRASNTWKVECFLPRLWTYSGCCSVFLDTSQWTEIFPDET----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *:***** *.**. .:*:**: * * **:.**** .*.:::****.:*** * ***:**:*** **: *****:**:* :..*:**.***:***.: ***.* ::::*:* :*:.** ****:*:**:***** **** :* *.****:** ****** :.:***** ::**.:** .: *::: ::* **:: ****. : * . * ***.*.:*. :... : : * .***:*:* .: :. :*: : :***.*:**::*:: :: .*: * .***.* :*: *****:*:***:*: :**.::********::::*****::* : :*. * .*****:.****:*::******.****: * ** ***:::.*: . ** ***:**:*: *.*:***:**.* *** *::***.** * *.:*.***:******* ..::.* :*********** ***.:*:*:*:* : ***** ** ** *:****:*:**:*** **:* *: . ::* . ***** * *..::*** *:**: ", "identical_positions": 292, "similar_positions": 171, "identity": "48.75%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100913-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M4A4-1", "uniprot_id": "KIF1A_RAT", "id": "F1M4A4-1", "name": "Kinesin-like protein KIF1A", "aln": "MAGASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQP---KETPKSFSFDYSYWSHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETNITTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKKKKKTD-FIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAIINEDPNNKLIRELKDEVTRLRDLLYAQGLGDITDTNT---------------------------VPGGPKLTNALVGMSPSSSLSALSSRAASVSSLHERILFAPGSEEAIERLKETEKIIAELNETWEEKLRRTEAIRMEREALLAEMGVAMREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGVTRVGREDAERRQDIVLSGHFIKEEHCIFRSDSRGGGEAVVTLEPCEGADTYVNGKKVTEPSILRSGNRIIMGKSHVFRFNHPEQARQERERTP--------CAETPAEPVDWAFAQRELLEKQGIDMKQEMEQRLQELEDQYRREREEATYLLEQQRLDYESKLEALQKQMDS---------RYYPEVNEEEE----EPEDEVQWTERECELALWAFRKWKWYQFTSLRDLLWGNAIFLKEANAISVELKKKVQFQFVLLTDTLYSPLPPDLLPPEAAKDRE----TRPFPRTIVAVEVQDQKNGATHYWTLEKLRQRLDLMREMYDRAAEVPSSVVEDCDNVVTGGDPFYDRFPWFRLVG-----------------------------------------------------------------------------------------------------RAFVYLSNLLYPVPLVHRVAIVSEKGEVKGFLRVAVQAIS-------ADEEAPDYGSGVRQSGTAKISFDDQHFEKFQSESCPVVGMSRSGTSQEELRIVEGQGQGADAGPSADEVNNNTCSAVPPEG-LLDSPEKAALDGPLDTALDHLRLGSTFTFRVTVLQASSISAEYADIFCQFNFIHRHDEAFSTEPLKNTGRGPPLGFYHVQNIAVEVTKSFIEYIKSQPIVFEVFGHYQQHPFPPLCKDVLSPLRPSRRHFPRVMPLSK-------------------------------------------------------------------------PVPATKLSTMTRPSPGPCHCKYDLLVYFEICELEANGDYIPAVVDHRGGMPCMGTFLLHQGIQRRITVTLLHETGSHIRWKEVRELVVGRIRNTPET-DEALIDPNILSLNILSSGYVHPAQDDRQFLDSDIPRTFYQFEAAWDSSMHNSLLLNRVTPYREKIYMTLSAYIEMENCTQPAVITKDFCMVFYSRDAKLPASRSIRNLFGSGSLRATEGNRVTGVYELSLCHVADAGSPGMQRRRRRVLDTSVAYVRGEENLAGWRPRSDSLILDHQWELEKLSLLQEVEKTRHYLLLREKLETTQRPVPEVLSPASSEDSESRSSSG---------ASSPLSAEGQPSPLEVPNERQRELAVKCLRLLMHTFNREYTHSHVCISASESKLSEMSVTLMRDPSMSPLGAATLTPSSTCPSLIEGRYG-ATDVRTPQPCSRPASPEPELLPELDSKKTPSPVRATETEKEPQRLLVPDIQEIRVSPIVSKKGYLHFLEPHTAGWAKRFVVVRRPYAYMYNSDKDTVERFVLNLSTAQVEYSEDQQAMLKTPNTFAVCTEHRGILLQANSDKDMHDWLYAFNPLLAGTIRSKLSRR-------RSAQMRV-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P33173-1", "uniprot_id": "KIF1A_MOUSE", "id": "P33173-1", "name": "Kinesin-like protein KIF1A", "aln": "MAGASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQP---KETPKSFSFDYSYWSHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKPRTVAATNMNETSSRSHAVFNIIFTQKRHDAETNITTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKKKKKTD-FIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAIINEDPNNKLIRELKDEVTRLRDLLYAQGLGDITD------------------------------------MTNALVGMSPSSSLSALSSRAASVSSLHERILFAPGSEEAIERLKETEKIIAELNETWEEKLRRTEAIRMEREALLAEMGVAMREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGVTRVGREDAERRQDIVLSGHFIKEEHCIFRSDSRGGGEAVVTLEPCEGADTYVNGKKVTEPSILRSGNRIIMGKSHVFRFNHPEQARQERERTP--------CAETPAEPVDWAFAQRELLEKQGIDMKQEMEQRLQELEDQYRREREEATYLLEQQRLDYESKLEALQKQMDS---------RYYPEVNEEEE----EPEDEVQWTERECELALWAFRKWKWYQFTSLRDLLWGNAIFLKEANAISVELKKKVQFQFVLLTDTLYSPLPPDLLPPEAAKDRE----TRPFPRTIVAVEVQDQKNGATHYWTLEKLRQRLDLMREMYDRAAEVPSSVVEDCDNVVTGGDPFYDRFPWFRLVG-----------------------------------------------------------------------------------------------------RAFVYLSNLLYPVPLVHRVAIVSEKGEVKGFLRVAVQAIS-------ADEEAPDYGSGVRQSGTAKISFDDQHFEKFQSESCPVVGMSRSGTSQEELRIVEGQGQGADAGPSADEVNNNTCSAVPPEG-LMDSPEKAALDGPLDTALDHLRLGSTFTFRVTVLQASSISAEYADIFCQFNFIHRHDEAFSTEPLKNTGRGPPLGFYHVQNIAVEVTKSFIEYIKSQPIVFEVFGHYQQHPFPPLCKDVLSPLRPSRRHFPRVMPLSK-------------------------------------------------------------------------PVPATKLSTMTRPSPGPCHCKYDLLVYFEICELEANGDYIPAVVDHRG--ACMGTFLLHQGIQRRITVTLLHETGSHIRWKEVRELVVGRIRNTPET-DEALIDPNILSLNILSSGYVHPAQDDRVFFGNDT-RTFYQFEAAWDSSMHNSLLLNRVTPYREKIYMTLSAYIEMENCTQPAVITKDFCMVFYSRDAKLPASRSIRNLFGSGSLRATEGNRVTGVYELSLCHVADAGSPGMQRRRRRVLDTSVAYVRGEENLAGWRPRSDSLILDHQWELEKLSLLQEVEKTRHYLLLREKLETTQRPGPEVLSPASSEDSESRSSSG---------ASSPLSAEGQPSPLEAPNERQRELAVKCLRLLMHTFNREYTHSHVCISASESKLSEMSVTLMRDPSMSPLGAATLTPSSTCPSLIEGRYG-ATDVRTPQPCSRPASPEPELLPELDSKKTPSPVRATETEKEPQRLLVPDIQEIRVSPIVSKKGYLHFLEPHTAGWAKRFVVVRRPYAYMYNSDKDTVERFVLNLSTAQVEYSEDQQAMLKTPNTFAVCTEHRGILLQANSDKDMHDWLYAFNPLLAGTIRSKLSRR-------RSAQMRV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12756-1", "uniprot_id": "KIF1A_HUMAN", "id": "Q12756-1", "name": "Kinesin-like protein KIF1A", "aln": "MAGASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQP---KETPKSFSFDYSYWSHTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQGIIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETNITTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKKKKKTD-FIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAVINEDPNNKLIRELKDEVTRLRDLLYAQGLGDITD------------------------------------MTNALVGMSPSSSLSALSSRAASVSSLHERILFAPGSEEAIERLKETEKIIAELNETWEEKLRRTEAIRMEREALLAEMGVAMREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGREDGERRQDIVLSGHFIKEEHCVFRSDSRGGSEAVVTLEPCEGADTYVNGKKVTEPSILRSGNRIIMGKSHVFRFNHPEQARQERERTP--------CAETPAEPVDWAFAQRELLEKQGIDMKQEMEQRLQELEDQYRREREEATYLLEQQRLDYESKLEALQKQMDS---------RYYPEVNEEEE----EPEDEVQWTERECELALWAFRKWKWYQFTSLRDLLWGNAIFLKEANAISVELKKKVQFQFVLLTDTLYSPLPPDLLPPEAAKDRE----TRPFPRTIVAVEVQDQKNGATHYWTLEKLRQRLDLMREMYDRAAEVPSSVIEDCDNVVTGGDPFYDRFPWFRLVG-----------------------------------------------------------------------------------------------------RAFVYLSNLLYPVPLVHRVAIVSEKGEVKGFLRVAVQAIS-------ADEEAPDYGSGVRQSGTAKISFDDQHFEKFQSESCPVVGMSRSGTSQEELRIVEGQGQGADVGPSADEVNNNTCSAVPPEGLLLDSSEKAALDGPLDAALDHLRLGNTFTFRVTVLQASSISAEYADIFCQFNFIHRHDEAFSTEPLKNTGRGPPLGFYHVQNIAVEVTKSFIEYIKSQPIVFEVFGHYQQHPFPPLCKDVLSPLRPSRRHFPRVMPLSK-------------------------------------------------------------------------PVPATKLSTLTRPCPGPCHCKYDLLVYFEICELEANGDYIPAVVDHRGGMPCMGTFLLHQGIQRRITVTLLHETGSHIRWKEVRELVVGRIRNTPET-DESLIDPNILSLNILSSGYIHPAQDDR---------TFYQFEAAWDSSMHNSLLLNRVTPYREKIYMTLSAYIEMENCTQPAVVTKDFCMVFYSRDAKLPASRSIRNLFGSGSLRASESNRVTGVYELSLCHVADAGSPGMQRRRRRVLDTSVAYVRGEENLAGWRPRSDSLILDHQWELEKLSLLQEVEKTRHYLLLREKLETAQRPVPEALSPAFSEDSESHGSSS---------ASSPLSAEGRPSPLEAPNERQRELAVKCLRLLTHTFNREYTHSHVCVSASESKLSEMSVTLLRDPSMSPLGVATLTPSSTCPSLVEGRYG-ATDLRTPQPCSRPASPEPELLPEADSKKLPSPARATETDKEPQRLLVPDIQEIRVSPIVSKKGYLHFLEPHTSGWARRFVVVRRPYAYMYNSDKDTVERFVLNLATAQVEYSEDQQAMLKTPNTFAVCTEHRGILLQAASDKDMHDWLYAFNPLLAGTIRSKLSRR-------RSAQMRV-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QG12-1", "uniprot_id": "A0A8M9QG12_DANRE", "id": "A0A8M9QG12-1", "name": "plus-end-directed kinesin ATPase", "aln": "MAGASVKVAVRVRPFNSREIGKESKCIIQMSGNTTTIINPKAP---KEN-KSFNFDYSYWSHTSPEDINYASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEKDQQGIIPLLCEDLFTKINENNDNNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVMSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQRRHDSETDNTSEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVDSGSNKNKKKKKVESFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAVINEDPNNRLVRELKDEVSRLKDLLYAQGLGDIIETFRGPVEDFAGLKYISDYKNHNNNGQALNQRGDFSTVTNAMTGMSPSPSLSALSSRAGSISSLHDRIMFSPGSEEAIERLKETEKIIAELNETWEEKLRRTEAIRMDREALLAEMGVAMREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGREDASSRQDIVLSGHFIKEEHCTFTSTTGPMGEAVI-LEPCEGAETYVNGKRVTEPTVLKSGNRIILGKSHVFRFNHPEQARQERDRTP--------CAETPVEPVDWAFAQRELLDKQGIDMKQEMDQRLQELEDQYRKEREEANNLLEQQRLDYESRLEALQKQVD----------RCYPDAAEEDE----EPEEEVQWTERETELAMWAFRKWRCYQFTSLRDLLWGNAIFLKEANAISVELKKKVQFQFVLLTDTLYSPLPPDLLPPEAAKDRE----KSPFPRTIVAVEVQDQKNGATHYWTLEKLRQRLDLMREMYDRAAEVPSNAVEDCDSVLTGGDPFYDRFPWFRLVGRNPLFSTCLSEQASDPNSSPTPSEPTSTSELTELVQSWPDKKVGTELDDDGFLSDDPCSDLEEEGEDDDDDDVDDDEELCRSSGKAEDPFYDRSPLFSVVGRAFVYLSNLLYPVPLVHRVAIVNEKGEVKGFLRVAVQAISGALVFPPADEEAPDYGSGVRQSGTAKISFEDQQFEKFQSESC-HSGLSRAAVSQEELRIVEGEGQSAEMGLSADEVNNNTCAAN-PEE--LDSPVKTGLDGMLDGALDHLRIGEVFTFRVTVLQASSISAEYADIFCQFNFIHRHDEAFSTEPLKNTGRGPPLGFYHVQNIAVEVTKSFIEYIKTQPIVFEVFGHYQKQPFPALCKDLISPLRPCRRQFPRVMPLSKPAADNDTPPDREKNLELIRYLLPEVFNGSLVDSLSSHALNAAGVAVSYLLEGEEQARLPAPPLSICSVIKAQKPVPATKLTALTRPTAGPCHCKYDLMVFFEICELEANGDYIPAVVDHRVGMPCHGTFMLHQGIQRRVTVTMVHETGRDIDWKEVRELVVGRIRNTPEA-DEAIIDPNILSLNILSAGYIRPTHDDRQFLDSDMPRTFYRFEAAWDSSMHNSLLLNRVTPYGEKIYMTLSAYLEMENCTQPTVITKDLCMVFHSRDAKLPASRSIRNLFSSGTLRPSEGNRVTGVYELSLCHLADAGSPGMQRRRRRVLDTSVAYVRGEENLAGWRPRSDSLILDHQWELEKLSLLQEVEKTRHYLLLREKLESTLLLGQESLLSCGSEDLTESSSPS---------THLGLGHNPGPGP-DTPNERQRELAAKCLRLLNHTFNRDY--SHVCVSASESKLSEMSVTLLKD-SASVCAESTLTPSSTCPSLVESRYIHNTDLRPPTPRSRAVSPNPD--SETDGKKIQEPRSRTRT-------FVPDIQEIRVSPIVSKKGYLHFLEPHSNGWVKRYVVVRRPYVYIYNSDRDTVERAILNLSSAQVEYSEDQQAMLKTPYTFAVCTEHRGILLQASNDKEMHDWLYAFNPLLAGSIRSKLSRR-------RAGQMRF-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZAJ2-1", "uniprot_id": "KIF1A_DROME", "id": "A1ZAJ2-1", "name": "Kinesin-like protein unc-104", "aln": "--MSSVKVAVRVRPFNSREIARESKCIIEMAGATTAITNPKVPPNTSDSVKRFNFDYSYWSHDH-HDADFSTQSMVYKDIGEEMLQHSFDGYNVCIFAYGQTGAGKSYTMMGRQEEQQEGIIPMICKDLFTRIQDTETDDLKYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTDYQDIHDLIDEGNKARTVAATNMNETSSRSHAVFTIFFTQRRHDLMTNLTTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVAS---KKKNTKKAD-FIPYRDSALTWLLRENLGGNSKTAMIAAISPADINYDETLSTLRYADRAKQIVCKAVVNEDANAKLIRELKEEIQKLRDLLKAEGIEVQEE--------------------------------------DELTKSTVIKSPTKSRNRNGSTT------------EMAVDQLQASEKLIAELNETWEEKLKRTEEIRVQREAVFAEMGVAVKEDGITVGVFSPKKTPHLVNLNEDPNLSECLLYYIKEGLTRLGTHEANVPQDIQLSGSHILKEHCTFENKN-----STVTLLPHKDAIIYVNGRKLVEPEVLKTGSRVILGKNHVFRFTNPEQARELRDKIETENEAENEVEKTDTQQVDWNFAQCELLEKQGIDLKAEMKKRLDNLEEQYKREKLQADQQFEEQRKTYEARIDALQKQVEEQSMTMSMYSSYSPEDFHQEEDVYTNPMYESCWTAREAGLAAWAFRKWRYHQFTSLRDDLWGNAIFLKEANAISVELKKKVQFQFTLLTDTLYSPLPPELASTVAPVHQEDEFGAPPVSKTLVAVEVTDTKNGATHHWSLEKLRQRLELMREMYHNEAEMSPTSPDYNVESLTGGDPFYDRFPWFRMVG-----------------------------------------------------------------------------------------------------RSFIYLSNLLYPVPLVHKVAIVNERGDVRGYLRIAVQPVL--------DEESIDFNNGVKQS--ARLVFNEDDAKPKYRALNEKDDVQR-YIDNGGLDSKLEELEDVDSGRGIDSNSASECHENSEEP------------------GEHLQVGKEFTFRVTVLQATGIGAEYADIFCQFNFLHRHEEAFSTEPVKNSASGAPLGFYHVQNITVPVTKSFIEYLKTQPIMFKIFGHYQTHPLHKDAKQDFVSRPPPRRMLPPSIPISQ-------------------------------------------------------------------------PVRSPKFGPLPCAPTSTVLAKHDVLVWFEICELAPNGEYVPSVVEHSDDLPCRGLFLLHQGIQRRIRITIVHEPTTEVKWKDINELVVGRIRNTPESSDEQDEDACVLSLGLFPGEALEVPGDDR---------SFYRFEAAWDSSLHNSALLNRVSQGGETIYITLSAYLELENCARPAIITKDLSMVIYGRDART-GPRSLKHLFS-GQYRNPEANRLTGVYELALRRASEAGSPGVQRRQRRVLDTSSTYVRGEENLHGWRPRGDSLIFDHQWELEKLTRLEEVGRMRHLLLLRERLGMDTNPNPTTKTEKDVCNLAARAATSPVHMVIPQSPQTPVKDPQQIIPEREYNQREQDLMLKCLKLVQG----RYTKSEANDTQTQS-----------DVSPSDEGCADMTVSCISSNSME----------NNKFVIRRRLCSPDRADAPNGWEAPAPATQPALP---LRLYVPELEEIRVSPVVARKGLLNVLEHGGSGWKKRWVIVRRPYVFIYRSEKDPVERAVLNLATAHVECSEDQAAMVKIPNTFSVVTKHRGYLLQTLGDKEVHDWLYAINPLLAGQIKSRLARRTLEPASQTASQIQATNAANANSASK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***************:.::*****:*:* **:* *** * .:. * *.******** .* ::::*. **:******* *:*:**********************:**::*:**** :*:***::*::. :::.*********************************************** .*:**:**:*.***.*******************.*:***:*** *: *:*************************************************: * *:*:.**.: *******.*************:***:**:*********************** *:*::***.* :*:****:*: :*:*** *:*: : : :. : * : .* .* : * *:::*: :**:************:*** **::***::******::*** *:****************** :*********:*:**:* .:.. *** *** .* :*** * . . :.: * * :.* ****:::.** :*::*.*:*:**.*****.:*****: *:: :* .: *** *** ***:*****:* **.:**::**:**::*: :* :*:** **::::*****:: *: .::* :* * ** ** ** ******: :******* **************************.************:* .. *. .:* *..:*:***** * ******:*:********:******.. **:... : . :**************:** *:*:*************:****.*:*:*:*:**:***.: ***: *:..**:** *:: *:::. : .:.* .: * : :..: * . *. . . * * :**::*. **********:.*.************:***:*******:**:. *.**********:* ********:*:***:*::***** :*: .*: : . * ** :* :*:*: ** :.*: .:. . ... .*:*::*:****** .**:*:*:**:* .* * *:********: :*::**. .: **::.************: ** *. :***.::.. :. . *** :**:********:*** *****: *.**:*****:*:***::*:::***:.**::.***: ..**:::**. * * .*.**:******:* : ::*****:***:******* :******** *****.****:*********: *:** : ** *****:* : .:.. . : * *:*:::* ***:*: * *.. : ::* * * * . : :* *. ... :* * .*: :. : * . **:::******:*::** *:.** ** :*:*:*****.::*.*::*.*** :***::*:** **** **:* * **:* *:*** ***: .**::******:****** *:*:*:** :.*:: ", "identical_positions": 919, "similar_positions": 397, "identity": "46.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100914-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P22680-1", "uniprot_id": "CP7A1_HUMAN", "id": "P22680-1", "name": "Cytochrome P450 7A1", "aln": "MMTTSLIWGIAIAACCCLWLILG-IRRRQTGEPPLENGLIPYLGCALQFGANPLEFLRANQRKHGHVFTCKLMGKYVHFITNPLSYHKVLCHGKYFDWKKFHFATSAKAFGHRSID-PMDGNTTENINDTFIKTLQGHALNSLTESMMENLQRIMRPPVSSNSKTAAWVTEGMYSFCYRVMFEAGYLTIFGR-DLTRRDTQ-----KAHILNNLDNFKQFDKVFPALVAGLPIHMFRTAHNAREKLAESLRHENLQKRESISELISLRMFLNDTLSTFDDLEKAKTHLVVLWASQANTIPATFWSLFQMIRNPEAMKAATEEVKRTLENAGQKVSLEGNPICLSQAELNDLPVLDSIIKESLRLSSASLNIRTAKEDFTLHLE-DGSYNIRKDDIIALYPQLMHLDPEIYPDPLTFKYDRYLDENGKTKTTFYCNGLKLKYYYMPFGSGATICPGRLFAIHEIKQFLILMLSYFELELIEGQAKCPPLDQSRAGLGILPPLNDIEFKYKFKHL----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64505-1", "uniprot_id": "CP7A1_MOUSE", "id": "Q64505-1", "name": "Cytochrome P450 7A1", "aln": "MMSISLIWGIAVVVSCCIWFIIG-IRRRKVGEPPLDNGLIPYLGCALKFGSNPLEFLRAKQRKHGHVFTCKLMGKYVHFITNSLSYHKVLCHGKYFDWKKFHYTTSAKAFGHRSID-PSDGNTTENINKTFNKTLQGDALCSLSEAMMQNLQSVMRPPGLPKSKSAVWVTEGMYAFCYRVMFEAGYLTLFGK-DISKTDSQ-----RAFIQNNLDSFKQFDQVFPALVAGVPIHLFKTAHKARERLAESLKHKNLYMRDQVSELIRLRMFLNDTLSTFDDMEKAKTHLVILWASQANTIPATFWSLFQMIRSPEAMKAASEEVNGALQSAGQELSSGGNAIYLDQEQLNNLPVLDSIIKEALRLSSASLNIRTAKEDFTLHLE-DGSYNIRKDDIIALYPQLMHLDPEIYPDPLTFKYDRYLDESGKAKTTFYRNGNKLKYFYMPFGSGATICPGRLFAVQEIKQFLILMLSYFELELVESHTKCPPLDQSRAGLGILPPLNDIEFKYKLKH-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FCW9-1", "uniprot_id": "E7FCW9_DANRE", "id": "E7FCW9-1", "name": "", "aln": "-MSTFLFTVAAILLTLFIVWICGHTRKRKPGEPPLVTGWLPFIGVTKDYVSNPLGFLTETQKKHGNVFTCLIAGKYFTFVTDPFSFSSVVRQGKNLDFQKFAINFSQRVFGHADFNSPQLSGNYREIHSIFRQTLQGPSLQHLTQSMLCNLQTVLER---CLPHEHDWLEEGLQSFTNRIMFEAGFLTLFGKEDIGFLQDHGMSGNRISMPKATQDFLVFDHAFPLLAAGVPIGLCTKAWRAREALAEELLHDELHRRKCISDLIQRRMDIFDRM-LLDETGKARTHVCMLWASQANTLPAAFWSLYYTLKSVDAFTAARTEVNRVLL--GQSLNNKDQTVYLSKDQLDSMTVLESIIEEALRLSSASMMIRVASDDFTLTLESDQTAAIRKGDYIALYPQLLHLDPEIYPNPTEFKYNRFLDENDQPKTNFFKSGRRLRNFLMPFGSGASECPGRFFAVYEIKLFLALTLWHYDLQLRDPDVPVV-QDSARAGLGIMPPSQDVLLRFRKKQRTPGNEHKDTK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *: *: : * * *:*: ***** .* :*::* : .: :*** ** .*:***:**** : ***. *:*:.:*: .*: :** :*::** * :.*** .:: * ... .:*:. * :**** :* *:::*: *** ::. .: *: **: :* *:*****:**:**: *: : : : : : :.* **:.** *.**:** : .* .*** ***.* *.:* *. :*:** ** : * : :*: **:**: :********:**:****: ::. :*:.** **: .* **.:. .:.: *.: :*:.:.**:***:*:*******: **.*.:**** ** * : ***.* *******:********:* ***:*:***..:.**.*: .* :*: : *******: ****:**: *** ** * * :::*:* : .. *.:******:** :*: :::: *: ", "identical_positions": 216, "similar_positions": 156, "identity": "41.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100914-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AQP0-1", "uniprot_id": "MYH7B_MOUSE", "id": "A2AQP0-1", "name": "Myosin-7B", "aln": "------------------------------------------MMDMSELGESACYLRQGYQEMMKVHTVPWDGKKRVWVPDEQDAYVEAEVKTEATGGKVTVETKDQKVLTVRETEMQPMNPPRFDLLEDMAMMTHLNEAAVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTAAVVAAYKGKRRSEAPPHIYAVADNAYNDMLRNRENQSMLITGESGAGKTVNTKRVIQYFAIVAALGDGPGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPTGKLASADIDSYLLEKSRVIFQLPGERGYHVYYQILSGKKPELQDMLLLSMNPYDYHFCSQGVTTVDNMDDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWLVSRINQTLDTKLPRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPLGILSILEEECMFPKASDASFRAKLYDNHSGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQNRLLATLYENYAGSCSTEPPKSGVKEKRKKAASFQTVSQLHKENLNKLMTNLRATQPHFVRCIVPNENKTPGVMDSFLVLHQLRCNGVLEGIRICRQGFPNRLLYADFRQRYRILNPSAIPDDTFVDSRKATEKLLGSLDIDHTQYQFGHTKVFFKAGLLGILEELRDQRLAKVLTLLQARSRGRLMRLEYQRMLGGRDALFTIQWNIRAFNAVKNWSWMKLFFKMKPLLRSAQAEEELAALRAELRGLRGALATAEAKRQELEETQVSVTQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLEAKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLELTLAKAEKEKQATENKVKNLTEEMAALDEAVVRLTKEKKALQEAHQQALGDLQAEEDRVSALAKAKIRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQETVTDTTQDKQQLEEKLKKKDSELSQLNLRVEDEQLVGVQLQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAVLRHEATVAALRRKQADSAAELSEQVDSLQRIRQKLEKEKSELRMEVDDLGASVETLARGKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTENGELGRLLEEKESMISQLSRGKTSAAQSLEELRRQLEEESKAKGALAHAVQALRHDCDLLREQHEEESEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQREARGLGTELFRLRHSHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKAKKALEGEKSELQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECTNLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQAMEAQAATRLLQAQLKEEQAGRDEEQRLAAELREQGQALERRAALLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEVDLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELVYQTEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQASTNLAKYRKAQHELDDAEERADMAETQANKLRARSRDALG---PKHKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A7E2Y1-1", "uniprot_id": "MYH7B_HUMAN", "id": "A7E2Y1-1", "name": "Myosin-7B", "aln": "MSGNKRGSRASCPHRGAECLLPWAALNLQGFQLLLLHPSATAMMDVSELGESARYLRQGYQEMTKVHTIPWDGKKRVWVPDEQDAYVEAEVKSEATGGRVTVETKDQKVLMVREAELQPMNPPRFDLLEDMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTASVVAAYKGKRRSDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDGPGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKLASADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQDMLLLSMNPYDYHFCSQGVITVDNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNMKFKQKQREEQAEADGTESADKAAYLMGVSSGDLLKGLLHPRVRVGNEYVTKGQSVEQVVFAVGALAKATYDRLFRWLVSRINQTLDTKLPRQFFIGVLDIAGFEIFEFNSFEQLCINFTNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLIEKPLGILSILEEECMFPKASDASFRAKLYDNHAGKSPNFQQPRPDKKRKYQAHFEVVHYAGVVPYSIVGWLEKNKDPLNETVVPIFQKSQNRLLATLYENYAGSCSTEPPKSGVKEKRKKAASFQTVSQLHKENLNKLMTNLRATQPHFVRCIVPNENKTPGVMDAFLVLHQLRCNGVLEGIRICRQGFPNRLLYTDFRQRYRILNPSAIPDDTFMDSRKATEKLLGSLDLDHTQYQFGHTKVFFKAGLLGVLEELRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQWNIRAFNAVKNWSWMKLFFKMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETHVSITQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLELTLAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSALTKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLADASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALRLQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLARMQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAETQANKLRARTRDALG---PKHKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "R4GDZ5-1", "uniprot_id": "R4GDZ5_DANRE", "id": "R4GDZ5-1", "name": "", "aln": "---------------------------------------MSRMLDMKEFGEAAPFLRKSDLELLAAQTVAFDGKKRAWIPDDKDAYIEVEIK-QIDGDRVEVETKDGKCLTVKEDDIQQMNPPKFDLIEDMAMLTHLNEASVLFNLRRRYSSWMIYTYSGLFCVTVNPYKWLPVYTAPVVAAYKGKRRSEAPPHIYSIADNAYNDMLRNRENQSMLITGESGAGKTVNTKRVIQYFAIVAALGEAAAKK--------GGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPTGKLASADIDIYLLEKSRVIFQQPGERSYHIYYQIMSQKKPELLDMLLVSSNPYDYHFCSQGVTTVENMDDGQELMATDHAMDILGFTPEEKYGCYKIVGAIMHFGNMKFKQKQREEQAEADGTESADKASYLMGVSSADLIKGLLHPRVKVGNEYVVKGQNVEQVNYAVGALAKATYDRMFKWLVGRINRTLYTALPRQFFIGVLDIAGFEIFELNSFEQLCINFTNEKLQQFFNHHMFILEQEEYKREGIEWTFIDFGLDLQACIDLIEKPLGIMSILEEECMFPKATDNSFKAKLFDNHLGKSANFQKPRPDKKRKYEAHFELVHYAGVVPYNIIGWLDKNKDPLNETVVICFQKSSNKLLASLYEKYVSSDSASDPKTGGKEKRKKAASFQTVSQLHKENLNKLMTNLRSTQPHFVRCIIPNETKTPGIMDSFMVLHQLRCNGVLEGIRICRKGFPNRMLYAEFKQRYRILNPHAIPDDKFVDSRKAAEKLLASLDIDHNQYRFGHTKVFFKAGLLGQLEEMRDERLAKILTLLQAASRGKIMRMELNKMTQRKEALMIIQWNIRAFNIVKNWPWMKLFFKIKPLLRSAATEKELAALKEEFLKLKEALEKSEAKRKELEEKQVSLIQEKNDLSLQLQAEQDNLADAEDRCDLLIKTKIQLEAKVKEMTERLEDEEEMNATVLAKKRKLEDECAELKKDIDDLEITLAKVEKEKHATENKVKNLIEEMAALDETILKLTKEKKALQESHQQTLDDLQTEEDKVNTLTKAKAKLEQQVDDLEGSLEQEKKLRMDLERSKRKLEGDLKLSMESVMDLENDKQQLEEKLKKKDFEMNQISSKIEDDQVLIIQLQKKIKELQARIEELEEEMEAERSTRAKMEKHRSDSSKELEELSERLEEAGGATSAQIEMNKKREADFLKLRRDLEEAILHHEAMTAALRKKHADSVVELSEQIDSLQRVKQKLEKERSEAKMEADDLTSNLEQLAKGKATAEKTCRLYEDQMNESKAKVEELQRQLSDTNTQRARAQAESAELGRKLEEREALVSQLQRSKNTFSQNIEELKKQLEEESKSKNALTHALQSSRHDCDLLREQYDEEQEGKSELQRALSKANAEVAQWRTKYETDAIQKTEELEEAKKKLATRLQESEEQVEASNAKCSSLEKTKHRLQSEIEDLVLDLERSNAAATALDKKQRQFDKILAEWRHKYEECQSELESSQKESRNLSTELFKLKNSYEEALDHLESIKRESKNLQEEISDLNDQISQGGKTIHELEKIKKGLDLEKTEIQAALEEAEGTLEHEESKTLRIQLELNQIKADTDRKLAEKDEEIDNLRRNHQRALESMQATLDAEAKSRSEAIRVKKKMENDLNEMEVQLNHANWLATESQKMVRNLQTQIKDLQMELDETVHQNEELKEQSAVTERRNNLLTAEVEELRCQLEQNDRARKLAEFELLETTERVNLLHSQNTSMLNQKKKLENDLATLSSEVDDAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQTIKDLQLRLDEAEQIALKGGKKQIQKLESKVRDLESELESEQKKSNELQKGIRKYERRIKELTYQTEEDRKNIARLQELIDKLQAKVKTYKRQAEDAEEQANSNLTKYKKIQHELDDAEERADIAESQVNKLRTRSRDSGSKTTPKLAE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*:.*:**:* :**:. *: .:*:.:*****.*:**::***:*.*:* : *.:* ***** * * *:* ::* ****:***:*****:******:**.***:**: *************:***********.***********::*****::************:********************************:...** ******************************************:********* *********** ****.**:****:* :**** ****:* ************ **:**:**:**:***********: :** .*******::***************************:*******.**:********:******.***.**** :************:*:***.***:** * *******************:********************:***:***********:*.*********.***********:************:* **:***:*** ***.***:*********:****:*********.*:***:*********** ****.*:***:***:*..* *:. **:* *****************************:*********:***.****:**:*:******************:*****:**::*:******** *****.*:*****:****.***:**.**:************** ***:**:****:****** ***::**:* ::: ::**: ********* ****.*******:******* :*:*****: *: *: ** :****:****.:**: ******:**************:**.****:*:***.****::********:** : *::*******:**********:****.****:********* ********:: :**********:***:*.***:***:*.:*:*** :*****:*** *********** **:**********: *:* * :************* *:.*:. ::**:*:: *:********** ******:****::**::**:*:::::***************::.* * :****:: :***:**** *:*** .****:*:*:...**.**:*****::******:** :**.*** :.:* *::.**:*** ** ****:.*:* *********:*:.***.* *:*..**.* ***:*.::***.*.* :*.:***::*******:*.**:**:*: **********::** *.::**** ************:***:****:************ ****:** ***:*********:* ***:* **:.*:***:.:**:*******:::: * * *:: ** * ***::*:*:*.*.****:*::.:****: **::***.**********.**:* .**:*:**** **.*: **:*:*********:** **:*********.*:**:.********** *********:**:**:****:::*.**:*:*****.***::*:**.**. * *:* .* :*:*:*: * ** : **:**. . *** **:**:****. ***.:*:*:*** ****:***:********.:******** *** **.**::*.** *:**********************************.:***:::** **:**** **:*****:****:***:**:**::**** * **:**:***:***.**:******:**:*:*:****:***:**** *:**:**.:**:**:* ************:**:*.****:*:**: . ** *", "identical_positions": 1412, "similar_positions": 383, "identity": "71.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100914-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08553-1", "uniprot_id": "DPYL2_MOUSE", "id": "O08553-1", "name": "Dihydropyrimidinase-related protein 2", "aln": "MS--YQGKKNIP---RITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIG--ENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDITEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDSQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTNCPLYVTKVMSKSAAEVIAQARK--KGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRISVGSDADLVIWDPDSVKTISAKTHNSALEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIK--ARSRLAELRGVPR-GLYDGPVCEVSVTPKTVTPASS--------------AKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47942-1", "uniprot_id": "DPYL2_RAT", "id": "P47942-1", "name": "Dihydropyrimidinase-related protein 2", "aln": "MS--YQGKKNIP---RITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIG--ENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDITEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDSQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRSITIANQTNCPLYVTKVMSKSAAEVIAQARK--KGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRISVGSDADLVIWDPDSVKTISAKTHNSALEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIK--ARSRLAELRGVPR-GLYDGPVCEVSVTPKTVTPASS--------------AKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q16555-1", "uniprot_id": "DPYL2_HUMAN", "id": "Q16555-1", "name": "Dihydropyrimidinase-related protein 2", "aln": "MS--YQGKKNIP---RITSDRLLIKGGKIVNDDQSFYADIYMEDGLIKQIG--ENLIVPGGVKTIEAHSRMVIPGGIDVHTRFQMPDQGMTSADDFFQGTKAALAGGTTMIIDHVVPEPGTSLLAAFDQWREWADSKSCCDYSLHVDISEWHKGIQEEMEALVKDHGVNSFLVYMAFKDRFQLTDCQIYEVLSVIRDIGAIAQVHAENGDIIAEEQQRILDLGITGPEGHVLSRPEEVEAEAVNRAITIANQTNCPLYITKVMSKSSAEVIAQARK--KGTVVYGEPITASLGTDGSHYWSKNWAKAAAFVTSPPLSPDPTTPDFLNSLLSCGDLQVTGSAHCTFNTAQKAVGKDNFTLIPEGTNGTEERMSVIWDKAVVTGKMDENQFVAVTSTNAAKVFNLYPRKGRIAVGSDADLVIWDPDSVKTISAKTHNSSLEYNIFEGMECRGSPLVVISQGKIVLEDGTLHVTEGSGRYIPRKPFPDFVYKRIK--ARSRLAELRGVPR-GLYDGPVCEVSVTPKTVTPASS--------------AKTSPAKQQAPPVRNLHQSGFSLSGAQIDDNIPRRTTQRIVAPPGGRANITSLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RM42-1", "uniprot_id": "A0A8M1RM42_DANRE", "id": "A0A8M1RM42-1", "name": "Dihydropyrimidinase-related protein 2", "aln": "MSG-YQGKKNIP---RITSDRLLIKGAKIVNDDQSFHADIYMEDGVIKQIG--ENLIVPGGVKIIEAHGRMLIPGGIDVHTRFQMPDRGMTAADDFYQGTRAALAGGTTMIMDHVVPEPGFSLISAFNQWREWADQKSCCDYSLHVDITEWHKGLQEEIEMLVKDHGVNSFLVYLAYKDIFQLNDSQMYEVFSVIRDLGAIAQVHAENGDIIAEEQKRILGLGITGPEGHVLSRPEEVEAEAVNRAVTIANQTNCPLYITKVMSKSAADVIAQARK--KGTVVYGEPISASLGTDGTHYWSKNWAKAAAFITSPPLSPDPTTPDYLNSLLACGDLQVTGSAHCTFNTSQRAVGKDNFTFIPEGTNGTEERMSIIWDKCVVTGKMDENQFVLVTSTNAAKIFNLYPRKGRIAVGSDADLVLWDPDATKIISAKSHHLAVEYNIFEGMEVRGAPLVVISQGKVVLEEGNLHTTEGSGRYISRKPFPDYVYKRIK--ARSRLAELRGVPR-GLYDGPVCEVTVTPKVMTPVTS--------------GKTSPVKPAPQPVRNLHQSGFSLSGAQVDDNVPRRTTQRIVAPPGGRANITSLG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IPQ2-1", "uniprot_id": "Q8IPQ2_DROME", "id": "Q8IPQ2-1", "name": "dihydropyrimidinase", "aln": "MSTSPKPVKKVPIHLQSAQNRVYIKNGEIVNHDKSFKADVYIEDGIIKFVGPSSEITIPGGVRTIDASGLMIIPGGIDPHTHMQLPFGGAVAVDDFYHGTKAAVAGGTTMIIDFVLPNKHESMIEAYDKWRSWADPKVCCDYGLHVGITWWSKSVSEEIGILCKELGVNSFKTFMAYKGLYQLNDSDLLDVFERIRHLNGVAMVHAENGDIIAKNTQRLLAEGINGPEGHELSRPEEVEAEAVHRACVLAHQADCPLYVVHVMSKSAGIELARARHRYRGRYIMGETLAAALGTDATCCQHLGFDAEAAHVLSPPLRPDKTTPEFLMKLLANDDLQLTGSDNCTFNKEHKALGKGDFTKIPNGVNGVEDRMSLVWEKGVHAGLLDPCRFVAVTSTNAAKIFNIYPQKGRIAVGSDADIVIWNPNATRTISKDTHHHACDFNIFEGMTVHGVCEFVLVRGRICAERGNVRVAEGFGRFIPTPVRPPFVYDIIEGKVQSQPEEQHEEKQNGSMAKRFAELDIQIPVQEPISAMLAGNLAMPAEGSLCSTPSVRGRVDGKRDLQESSFSIS--EELDRSGVRACIKVKNPPGGKS--SGFW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : *::* : :.:*: **..:***.*:** **:*:***:** :* .:: :****: *:* . *:****** **::*:* * .:.***::**:**:*******:*.*:*: *:: *:::**.*** * ****.***.*: * *.:.**: * *: ***** .::*:*. :**.*.:: :*:. **.:..:* **********:: :*:* **.***** ************:*: .:*:*::****:.:*****:. :*:**: :* : **.::*:****.: .: **.: **** ** ***::* .**: .***:*** :****. ::*:**.:** **:*.**.*:***::*:* * :* :* :** ********:**:**:****:******:*:*:*::.: ** .:*: : ::****** :* .*: :*:: * *.::.:** **:*. * :**. *: .:*: * : : * ..*: : . * :: .*...: *:*::*.**:* : *. *: :: ****:: :.: ", "identical_positions": 258, "similar_positions": 191, "identity": "43.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100917-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P30427-1", "uniprot_id": "PLEC_RAT", "id": "P30427-1", "name": "Plectin", "aln": "MVAGMLMPLDQLRAIYEVLFREGVMVAKKDRRPRSLHPHVPGVTNLQVMRAMTSLKARGLVRETFAWCHFYWYLTNEGIDHLRQYLHLPPEIVPASLQRVRRPVAMVMPARRRSPHVQTMQGPLGCPPKRGPLPAEDPAREERQVYRRK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EREEGAPETPVVSATIVGTLARPGPEPTPAT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DERDRVQKKTSTKWVNKHLIK-----AQRHISDLYEDLRDGHNLISLLEVLSGDSLPREK------------GRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFKIS----DIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFNAIIHRHKPMLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSLYDAMPRVPGAQDGVRANELQLRWQEYRELVLLLLQWIRHHTAAFEERKFPSSFEEIEILWCQFLKFKETELPAKEADKNRSKGIYQSLEGAVQAGQLKIPPGYHPLDVEKEWGKLHVAILEREKQLRSEFERLECLQRIVSKLQMEAGLCEEQLYQADSLLQSDIRLLASGKAAQRAGEVERDLDKADGMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLK-AGVGAP---VTQVTLQSTQR-RPELEDSTLRYLHDLLAWVEENQRRIDGAEWGVDLPSVEAQLGSHRGMHQSIEEFRAKIERARNDESQLSPATRGAYRDCLGRLDLQYAKLLNSSKARLRSLESLHGFVAAATKELMWLNEKEEEEVGFDWSDRNTNMAAKKESYSALMRELEMKEKKIKEIQNTGDRLLREDHPARPTVESFQAALQTQWSWMLQLCCCIEAHLKENTAYFQFFSDVREAEEQLQKLQETLRRKYSCDRSITVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAIVQLKPRNPAHPVRGHVPLLAVCDYKQVEVTVHKGDQCQLVGPAQPFHWKVLSSSGSEAAVPSVCFLVPPPNQEAQEAVARLEAQHQALVTLWHQLHVDMKSLLAWQSLNRDIQLIRSWSLVTFRTLKPEEQRQALRNLELHYQAFLRDSQDAGGFGPEDRLVAEREYGSCSRHYQQLLQSLEQ-------GEQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKDPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQVRSLSAIYLEKLKTISLVIRSTQGAEEVLKTHEEHLKEAQAVPATLQELEVTKASLKKLRAQAEAQQPVFNTLRDELRGAQEVGERLQQRHGERDVEVERWRERVTQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLSSWLQDAKSRQEQIQAVPIANSQAAREQLRQEKALLEEIERHGEKVEECQKFAKQYINAIKDYELQLITYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTRYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAELEARELQRRMQEEVTRREEAAVDAQQQKRSIQEELQHLRQSSEAEIQAKAQQVEAAERSRMRIEEEIRVVRLQLETTERQRGGAEDELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEAELALRVKAEAEAAREKQRALQALDELKLQAEEAERWLCQAEAERARQVQVALETAQRSAEVELQSKRPSFAEKTAQLERTLQEEHVTVTQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQADAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLTEGTAQQRLAAEQELIRLRAETEQGEHQRQLLEEELARLQHEATAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEARRHRELAEEDAARQRAEADGVLTEKLAAISEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASESELERQKGLVEDTLRQRRQVEEEIMALKASFEKAAAGKAELELELGRIRSNAEDTMRSKELAEQEAARQRQLAAEEEQRRREAEERVQRSLAAEEEAARQRKVALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFVVQQREEELQQTLQQEQNMLERLRSEAEAARRAAEEAEEAREQAEREAAQSRKQVEEAERLKQSAEEQAQAQAQAQAAAEKLRKEAEQEAARRAQAEQAALKQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKSILDEELQRLKAEVTEAARQRSQVEEELFSVRVQMEELGKLKARIEAENRALILRDKDNTQRFLEEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQADKEQMAQQLVEETQGFQRTLEAERQRQLEMSAEAERLKLRMAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDQDAERLREAIAELEREKEKLKQEAKLLQLKSEEMQTVQQEQILQETQALQKSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAKQLQEEQQRQQQQMEQEKQELVASMEEARRRQREAEEGVRRKQEELQRLEQQRQQQEKLLAEENQRLRERLQRLEEEHRAALAHSEEIATSQAAATKALPNGRDALDGPSMEAEPEYTFEGLRQKVPAQQLQEAGILSMEELQRLTQGHTTVAELTQREDVRHYLKGGSSIAGLLLKPTNEKLSVYTALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKDPYTGEQISLFQAMKKDLIVRDHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLRLLPLTDKAAKGGELVYTDTEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKIVITVVEEHERKGQLCFEGLRALVPAAELLDSGVISHEVYQQLQRGERSVREVAEADEVRQALRGTSVIAGVWLEEAGQKLSIYEALRRDLLQPEVAVALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEMHEKLLSAEKAVTGYRDPYSGQSVSLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVAYARGYLDKETNRALTSPRDDARVYLDPSTREPVTYSQLQQRCRSDQLTGLSLLPLSEKAVRARQEEVYSELQARETLEKAKVEVPVGGFKGRALTVWELISSEYFTEEQRQELLRQFRTGKVTVEKVIKILITIVEEVETQRQERLSFSGLRAPVPASELLASKILSRTQFEQLKDGKTSVKDLSEVGSVRTLLQGSGCLAGIYLEDSKEKVTIYEAMRRGLLRASTATLLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEKLLSAEKAVTGYKDPYSGSTISLFQAMKKGLVLRDHAIRLLEAQIATGGIIDPVHSHRLPVDVAYQRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLRLLPLRGAEKTEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSSMSLWEVMQSDMIPEDQRARLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQNLASYDYVRRRLTAEDLYEARIISLETYNLFREGTKSLREVLEMESAWRYLYGTGSVAGVYLPGSRQTLTIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQPISLFQAMKKELIPAEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSEVRSYVDPSTDERLSYTQLLKRCRRDDNSGQMLLPLSDARKLTFRGLRKQITVEELVRSQVMDEATALQLQEGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMIIDRRSGRQYDIGDAITKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSSYPISSAVP-RTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTEAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVSLDEALQRGTVDARTAQKLRDVSAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSSKGYYSPYSVSGSGSTAGSRTGSRTGSRAGSRRGSFDATGSGFSMTFSSSSYSSSGYGRRYASGPSASLGGPESAVA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QXS1-1", "uniprot_id": "PLEC_MOUSE", "id": "Q9QXS1-1", "name": "Plectin", "aln": "MVAGMLMPLDRLRAIYEVLFREGVMVAKKDRRPRSLHPHVPGVTNLQVMRAMASLKARGLVRETFAWCHFYWYLTNEGIDHLRQYLHLPPEIVPASLQRVRRPVAMVIPARRRSPHVQTMQGPLGCPPKRGPLPAEDPAREERQVYRRK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EREEGAPETPVVSATTVGTLARPGPEPAPAT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DERDRVQKKTFTKWVNKHLIKHWRAEAQRHISDLYEDLRDGHNLISLLEVLSGDSLPREK------------GRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTTSWRDGRLFNAIIHRHKPMLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSLYDAMPRVPGAQDGVRANELQLRWQEYRELVLLLLQWIRHHTAAFEERKFPSSFEEIEILWCQFLKFKETELPAKEADKNRSKVIYQSLEGAVQAGQLKIPPGYHPLDVEKEWGKLHVAILEREKQLRSEFERLECLQRIVSKLQMEAGLCEEQLNQADALLQSDIRLLASGKVAQRAGEVERDLDKADGMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLK-AGVGAP---VTQVTLQSTQR-RPELEDSTLRYLQDLLAWVEENQRRIDSAEWGVDLPSVEAQLGSHRGMHQSIEEFRAKIERARNDESQLSPATRGAYRDCLGRLDLQYAKLLNSSKARLRSLESLHGFVAAATKELMWLNEKEEEEVGFDWSDRNTNMAAKKESYSALMRELEMKEKKIKEIQNTGDRLLREDHPARPTVESFQAALQTQWSWMLQLCCCIEAHLKENTAYFQFFSDVREAEEQLQKLQETLRRKYSCDRTITVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAIVQLKPRNPAHPVRGHVPLIAVCDYKQVEVTVHKGDQCQLVGPAQPSHWKVLSGSSSEAAVPSVCFLVPPPNQEAQEAVARLEAQHQALVTLWHQLHVDMKSLLAWQSLSRDIQLIRSWSLVTFRTLKPEEQRQALRNLELHYQAFLRDSQDAGGFGPEDRLVAEREYGSCSRHYQQLLQSLEQ-------GEQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKDPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQVRSLSAIYLEKLKTISLVIRSTQGAEEVLKTHEEQLKEAQAVPATLQELEATKASLKKLRAQAEAQQPVFNTLRDELRGAQEVGERLQQRHGERDVEVERWRERVTQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLSAWLQDAKRRQEQIQAVPIANCQAAREQLRQEKALLEEIERHGEKVEECQKFAKQYINAIKDYELQLITYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTRYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAELEAQELQRRMQEEVARREEAAVDAQQQKRSIQEELQHLRQSSEAEIQAKAQQVEAAERSRMRIEEEIRVVRLQLETTERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEAELALRVKAEAEAAREKQRALQALDELRLQAEEAERRLRQAEAERARQVQVALETAQRSAEVELQSKRASFAEKTAQLERTLQEEHVTVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQADAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQHEATAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLTEKLAAISEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAALHKADIEERLAQLRKASESELERQKGLVEDTLRQRRQVEEEIMALKVSFEKAAAGKAELELELGRIRSNAEDTMRSKEQAELEAARQRQLAAEEEQRRREAEERVQRSLAAEEEAARQRKVALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFVVQQREEELQQTLQQEQNMLDRLRSEAEAARRAAEEAEEAREQAEREAAQSRKQVEEAERLKQSAEEQAQAQAQAQAAAEKLRKEAEQEAARRAQAEQAALKQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKSILDEELQRLKAEVTEAARQRSQVEEELFSVRVQMEELGKLKARIEAENRALILRDKDNTQRFLEEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLVEETQGFQRTLEAERQRQLEMSAEAERLKLRMAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLKQEAKLLQLKSEEMQTVQQEQILQETQALQKSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAKQLREEQQRQQQQMEQEKQELMASMEEARRRQREAEEGVRRKQEELQHLEQQRQQQEKLLAEENQRLRERLQRLEEEHRAALAHS-EIATTQAASTKALPNGRDAPDGPSVEAEPEYTFEGLRQKVPAQQLQEAGILSQEELQRLAQGHTTVAELTQREDVYRYLKGRSSIAGLLLKPTNEKLSVYTALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKDPYTGEQISLFQAMKKDLIVRDHGVRLLEAQIATGGIIDPVHSHRVPVDVAYKRGYFDEEMNRILSDPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLRLLPLTDKAAKGGELVYTDTEARDVFEKATVSAPFGKFQGRTVTIWEIINSEYFTAEQRRDLLQQFRTGHITVEKIIKIVITVVEEHERKGQLCFEGLRALVPAAELLDSGVISHELYQQLQRGERSVREVAEADSVRQALRGTNVIAGVWLEEAGQKLSIYEALKKDLLQPEVAVALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPELHEKLLSAEKAVTGYRDPYSGQSVSLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVAYARGYLDKETNRALTSPRDDARVYHDPSTQEPVTYSQLQQRCRSDQLTGLSLLPLSEKAVRARQEEVYSELQARETLEQAKVEVPVGSFKGRAMTVWELISSEYFTEEQRQELLRQFRTGKVTVEKVIKIVITIVEEVETRRQERLSFSGLRAPVPASELLDAKILSRAQFDQLKDGKTSVKELSEVGSVRTLLQGSGCLAGIYLEDSKEKVTIYEAMRRGLLRPSTATLLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEKLLSAEKAVTGYKDPYSGNTISLFQAMKKGLVLRDHAIRLLEAQVATGGIIDPVHSHRLPVDVAYQRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLRLLPLKGAEKTEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSSMSLWEVMQSNMIPEDQRARLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQNLASYDYVRRRLTAEDLYEARIISLETYNLFREGTKNLREVLEMESAWRYLYGTGAVAGVYLPGSRQTLTIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPAEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSEVRSYVDPSTDERLSYTQLLKRCRRDDPSGQMLLLLSDARKLTFRGLRKQITVEELVRSQVMDEATALQLQEGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMIIDRRSGRQYDIDDAITKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSSYPISSAGP-RTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTEAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVSLDEALQRGTVDARTAQKLRDVSAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSSKGYYSPYSVSGSGSTAGSRTGSRTGSRAGSRRGSFDATGSGFSMTFSSSSYSSSGYGRRYASGPSASLGGPESAVA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15149-1", "uniprot_id": "PLEC_HUMAN", "id": "Q15149-1", "name": "Plectin", "aln": "MVAGMLMPRDQLRAIYEVLFREGVMVAKKDRRPRSLHPHVPGVTNLQVMRAMASLRARGLVRETFAWCHFYWYLTNEGIAHLRQYLHLPPEIVPASLQRVRRPVAMVMPARR-TPHVQAVQGPLGSPPKRGPLPTE-----EQRVYRRK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ELEEVSPETPVVPATTQRTLARPGPEPAPAT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DERDRVQKKTFTKWVNKHLIK-----AQRHISDLYEDLRDGHNLISLLEVLSGDSLPREK------------GRMRFHKLQNVQIALDYLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQIS----DIQVSGQSEDMTAKEKLLLWSQRMVEGYQGLRCDNFTSSWRDGRLFNAIIHRHKPLLIDMNKVYRQTNLENLDQAFSVAERDLGVTRLLDPEDVDVPQPDEKSIITYVSSLYDAMPRVPDVQDGVRANELQLRWQEYRELVLLLLQWMRHHTAAFEERRFPSSFEEIEILWSQFLKFKEMELPAKEADKNRSKGIYQSLEGAVQAGQLKVPPGYHPLDVEKEWGKLHVAILEREKQLRSEFERLECLQRIVTKLQMEAGLCEEQLNQADALLQSDVRLLAAGKVPQRAGEVERDLDKADSMIRLLFNDVQTLKDGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLK-AGVAAPATQVAQVTLQSVQR-RPELEDSTLRYLQDLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRGLHQSIEEFRAKIERARSDEGQLSPATRGAYRDCLGRLDLQYAKLLNSSKARLRSLESLHSFVAAATKELMWLNEKEEEEVGFDWSDRNTNMTAKKESYSALMRELELKEKKIKELQNAGDRLLREDHPARPTVESFQAALQTQWSWMLQLCCCIEAHLKENAAYFQFFSDVREAEGQLQKLQEALRRKYSCDRSATVTRLEDLLQDAQDEKEQLNEYKGHLSGLAKRAKAVVQLKPRHPAHPMRGRLPLLAVCDYKQVEVTVHKGDECQLVGPAQPSHWKVLSSSGSEAAVPSVCFLVPPPNQEAQEAVTRLEAQHQALVTLWHQLHVDMKSLLAWQSLRRDVQLIRSWSLATFRTLKPEEQRQALHSLELHYQAFLRDSQDAGGFGPEDRLMAEREYGSCSHHYQQLLQSLEQ-------GAQEESRCQRCISELKDIRLQLEACETRTVHRLRLPLDKEPARECAQRIAEQQKAQAEVEGLGKGVARLSAEAEKVLALPEPSPAAPTLRSELELTLGKLEQVRSLSAIYLEKLKTISLVIRGTQGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQEVGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLGAWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEEIERHGEKVEECQRFAKQYINAIKDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISETLRRMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAEREAKELQQRMQEEVVRREEAAVDAQQQKRSIQEELQQLRQSSEAEIQAKARQAEAAERSRLRIEEEIRVVRLQLEATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHTTVDELARREDVRHYLQGRSSIAGLLLKATNEKLSVYAALQRQLLSPGTALILLEAQAASGFLLDPVRNRRLTVNEAVKEGVVGPELHHKLLSAERAVTGYKDPYTGQQISLFQAMQKGLIVREHGIRLLEAQIATGGVIDPVHSHRVPVDVAYRRGYFDEEMNRVLADPSDDTKGFFDPNTHENLTYLQLLERCVEDPETGLCLLPLTDKAAKGGELVYTDSEARDVFEKATVSAPFGKFQGKTVTIWEIINSEYFTAEQRRDLLRQFRTGRITVEKIIKIIITVVEEQEQKGRLCFEGLRSLVPAAELLESRVIDRELYQQLQRGERSVRDVAEVDTVRRALRGANVIAGVWLEEAGQKLSIYNALKKDLLPSDMAVALLEAQAGTGHIIDPATSARLTVDEAVRAGLVGPEFHEKLLSAEKAVTGYRDPYTGQSVSLFQALKKGLIPREQGLRLLDAQLSTGGIVDPSKSHRVPLDVACARGCLDEETSRALSAPRADAKAYSDPSTGEPATYGELQQRCRPDQLTGLSLLPLSEKAARARQEELYSELQARETFEKTPVEVPVGGFKGRTVTVWELISSEYFTAEQRQELLRQFRTGKVTVEKVIKILITIVEEVETLRQERLSFSGLRAPVPASELLASGVLSRAQFEQLKDGKTTVKDLSELGSVRTLLQGSGCLAGIYLEDTKEKVSIYEAMRRGLLRATTAALLLEAQAATGFLVDPVRNQRLYVHEAVKAGVVGPELHEQLLSAEKAVTGYRDPYSGSTISLFQAMQKGLVLRQHGIRLLEAQIATGGIIDPVHSHRVPVDVAYQRGYFSEEMNRVLADPSDDTKGFFDPNTHENLTYRQLLERCVEDPETGLRLLPLKGAEKAEVVETTQVYTEEETRRAFEETQIDIPGGGSHGGSTMSLWEVMQSDLIPEEQRAQLMADFQAGRVTKERMIIIIIEIIEKTEIIRQQGLASYDYVRRRLTAEDLFEARIISLETYNLLREGTRSLREALEAESAWCYLYGTGSVAGVYLPGSRQTLSIYQALKKGLLSAEVARLLLEAQAATGFLLDPVKGERLTVDEAVRKGLVGPELHDRLLSAERAVTGYRDPYTEQTISLFQAMKKELIPTEEALRLLDAQLATGGIVDPRLGFHLPLEVAYQRGYLNKDTHDQLSEPSEVRSYVDPSTDERLSYTQLLRRCRRDDGTGQLLLPLSDARKLTFRGLRKQITMEELVRSQVMDEATALQLREGLTSIEEVTKNLQKFLEGTSCIAGVFVDATKERLSVYQAMKKGIIRPGTAFELLEAQAATGYVIDPIKGLKLTVEEAVRMGIVGPEFKDKLLSAERAVTGYKDPYSGKLISLFQAMKKGLILKDHGIRLLEAQIATGGIIDPEESHRLPVEVAYKRGLFDEEMNEILTDPSDDTKGFFDPNTEENLTYLQLMERCITDPQTGLCLLPLKEKKRERKTSSKSSVRKRRVVIVDPETGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITISSSDGVVKSMIIDRRSGRQYDIDDAIAKNLIDRSALDQYRAGTLSITEFADMLSGNAGGFRSRSSSVGSSSSYPISPAVS-RTQLASWSDPTEETGPVAGILDTETLEKVSITEAMHRNLVDNITGQRLLEAQACTGGIIDPSTGERFPVTDAVNKGLVDKIMVDRINLAQKAFCGFEDPRTKTKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPDTPGRVPLDEALQRGTVDARTAQKLRDVGAYSKYLTCPKTKLKISYKDALDRSMVEEGTGLRLLEAAAQSTKGYYSPYSVSGSGSTAGSRTGSRTGSRAGSRRGSFDATGSGFSMTFSSSSYSSSGYGRRYASGSSASLGGPESAVA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PDC8-1", "uniprot_id": "A0A8M9PDC8_DANRE", "id": "A0A8M9PDC8-1", "name": "", "aln": "MVAGMVMPLDNLRAIYEHLFRDGVMVAKKDKRPQTKHPEIAGVQNLQVIRAMGSLKSRGYVTETFAWRHFYWYLTNEGIVYLRDYLHLPAEIVPTPLQRVRRPVATLAVTRR-AERVQTIEGPTSYVPKPGKMGAE---KQDRQGYRRKTASTDEAEVIESNERTPQFRGRPMASAQIKPKGSWESKELPIRSDNRDYTKEMEPSARRKVAMHSFSHETHHAKPVEQERMVECTKTAFIQDMPKASPGVLTISSAAVESPLVPVHSEAIKEKPKVDVSRQSTSITTAKEAHHPTPSKLKVEKTEKALVSRKMDHVPNVASAEETIALESFVHAQENPKEEEFTKVTKQTTSTTTGALRATPSKPKVDKTQETMVAKNELDVSNESSKPPVSIEAAKTKPKQDVCIKVSEKTTVVNASKMAEGDAHLTSSGPKVDKSNNVPAVSAALEISAFKSSVSSVSTEAIKEIPKEESCVSKEITSKGDSNAASHHSQLKTKGEKRQKATKTKSVQDSTCVPPAEEMSVVKPSGSEAVKEKTEEEVCVKLSQQSALKGEGGIEKDAPHPTVSSPQVEKAQKTRKNKKVQDLPMFSSTVQSSEKAEKPKDDESTKVTKEITLPVTDESKMAIDAPHPTHVEKTVKTIVTKNVQDGTSLKSPVCSVPAETANEKSNKEVCGIVSQETSSKDDNKTAFSAPSKSKVGKTATRIKNVQDKPAISSAVETTVVASSTFSLSTETIKEQYKEKVCVIASQETPFKGDKKNYAFHSATSTQKMEKMQTTKTAQTKPAVSSAEEMMEVKSSMSTEAVNEKSKREVGGIVTQETTSNGDNKKDALHPAVSKSKVVKILESKNAHDSTVVSSWMEAEVKSTLISTDAEKPKEEVCLMVSQETTLTGGSTEDAPSKLKAEKTKKTKKAKKVQDVPMISSTEAATAAESSVISVPAEKPEEDALRKVPQEATFTATDESKIDFTPSKPGGPKGTKRTKNVQELTVKLEKEQVPAVQAEEVKSNIFVTPQTPSGMPKKEENVAGETAKKKAELNLKKGVTVTSAQAQANTTVQVTDKQHDSQTSQGVIEDDSTSYLKVHKEVAIPCAISISEVKAEVKGHKPVLSPKFQPTVAEEEMTTADSSKASEISTKAESKVDTPKSHQEKASTLTEEPKTPKDKDAEETSKPSKGKKKKKTSKTSAVKEIPSLAETEVVTPAQVDPSKAEDHRQVATSNNSAKTSPEGMHAPENRQPTAVQSEAPAHKGEVEPAQPVTEKREVQKGKTSSSRRQWEAPAASASAAPAGLAAQHTPLPAQGDPPSIAQHTDTQRSTHKHCKLSHSKAPAGPVDEKTGDGQAQTTDDAMRKKIVVVEEVIEVQQVVSPVAGQPTTSPVPKVAGDDLDYDVLEELAIERGLLEGEETFWDHSLQEPEEKTFPNFVEDERDRVQKKTFTKWVNKHLIKHWRSETQRHVNDLYEDLRDGHNLISLLEVLSGETLPRERDVVRSVRLPRERGRMRFHKLQNVQIALDFLRHRQVKLVNIRNDDIADGNPKLTLGLIWTIILHFQVSYSISDIQVNGQSDDMSAKEKLLFWSQRMVDGYHGIRCDNFTTSWRDGKLFNAIIHKHEPRLIDMPKVYRQTNMENLEQAFTVAEKELGVTRLLDPEDVDVPHPDEKSIITYVSSLYDAMPRVPDVQDGAKTNELELRWQEYYQLVTVLQQWIRHHVLIFEERRFPSSYEEVEILWRQFLKFKETELPPKESDKGRSKQLFQSFESAVQAGQIKVPPGYHPIDVEKEWGRLHVAILERERLLRIEFERLERLQQIVSKVQMESGVCEEQLNQTESLLQTDIRLLNAGKPAQHTVEVERDLDKADGMIRLLFNDVQMLKDGRHLQAEQMYRRVYRLHERLVNLRSDYNLRLKSTATAATHTTVTSISQKSVQRVRPELDEVTLRYAQDLLAWVEENQRRIDTAEWGIDLPTVESQLGSHRGLHQTIEDFRAKIERARADENQLSPASKGTYREYLGKLDLQYTKLLNTSKSRLRNLDQLYNFVNAATKELMWLNDKEEEEVNYDWSERNANMGAKKDNYSGLMRELELREKKVNDIQATGDRLIKDGHPGKKTVEAFTAGLQTQWSWILQLCCCIETHLKENTAYFQFFADVKEADERLKKMQDTMKKKYMCDRSTTATRLEDLLQDAVEEREQVNEFKNDIANLNKRAKSVIQLKPRDPTCPFRGKLPIQAVCDFKQMEITMHKGDECALINNSQPSRWKVLNRSGDEAVVPSICFLVPPVNKEAVESVSGLEAGHQQTVILWQKLHADLRALLSWQYLMKDIQLIRSWNITMFKTMKPDEYRLILRNLQLHYQDFLKDREESKLFNSSDNMQIERDYKETTQHFDNLLRTLEKGAAVRAQGEQDESVCKSYITQIKNLRLQIEDCESRTVARIRQPVDKDPLRDCIQKTADQKKVHVELDGIKKNLNKVSEKAEEVLSSADQS-SAPVLRSELDITLQKMDQTYNLSSIYLEKLKTIEVVIRNTQGAEDVVKKYENRLREVHTVPTNVQEVENYCSELKTMRVDAEKQRPVFDDMEGELAKASAVSQRMVQIHTERDAELEHYRQMLGSLQDRWRAVFAQMDLRQRELEQLGRQLGYYRESYDWLIRWIADAKQRQEKIQAVPIIDSKTLKEQLAQEKKLLEEIEKNKDKVDECQKYAKNYIDTIKDYELQLVAYKAQVEPLTSPLKKTKMESASDNIIQEYVTLRTRYSELMTLTSQYIKFITDTQRRLEDEEKAAEKLKAEERKKMAEMQAELDKQKQLAEAHAKAIAKAEKEAQELKLMMQEEVSKREFVAVDAERQKQNIQLELHELKNLSEQQIKSKSQQVEEALQSRVKIEEEIRIIRLQLETTMKQKSTAQEELMQLRSKAAEAERLRKAAQEEAEKLRKQVNEETQKKRIAEEELKLKSEAEKEAARQKQKALDDLDKLKMEVDEAERHMKQAEIEKERQIKLAQDAAQKSASAELQSKRMSFVEKTSKLEESLREKHGTVIQLQEEAERLKKQQEEADKAREDAEKELEKWRQKANEALRLRLQAEEEAHKKTLAQEDAEKQKDEAEREAKKRAKAEESALKQKDMAEQELERQRKLAESTAQQKLSAEHELIRLRADFDHAEQQRSLLEDELYRLKSEVSAAEQQRKQLEDELSKVRSEMEVLLQLKSKAEKDSMSTTEKSKQLLEAEAGKLRDLADEAAKLRAIAEEAKRQRQVAEEEAARQRAEAERILKEKLAAINEATRLKTEAEIALKEKEAENERLRRKADDEAYQRKALEDQASQHKQDIEQKINQLKKSSEMELDRQKTIVDETLKQKRIVEEEIRILKLNFEKASSGKLDLELELNKLKNIADETQQSRLRAEEEAEKLRKLALEEENRRREAEEKLKKITAAEQEAARQRQAAQDEVERLKKKADEARKQKEDADKEAERQIYAAKEAAEKAITAEQQVQSVLVQQKEDSLVQ---------KKLKEEFEKAKRLAQEAEKAKEKAEKEAALLRQQAEDAERQRQTAEVEATNQAKAQEEAERLRKDAELEAEKRAQAEAAALKQKQIADEEMARHKKHAEQTLKQKSQVEQELAKVKLRLDETDKQKSVLDEELHRLKDEVGDAVKQKAQVEEELFKVRIQMEELIKLKLRIEQENQRLIQKDKDNTQKFLAEEAENMKKLAEEAARLSIEAQETARMRHIAETDLAEQRALAEKMLKEKMQAIQEASKLRAEAEMLQRQKDLAQEQAQRLLEDKQLMQQRLKEETEGFQKSLEAERRRQLDIAAEAERLRLQVSQLSDAQSRAEDEAKRFKKQADDISARLHETELSTKERMTVVEKLEIQRLSSTREADDLRKAIADLENEKAKLKKDAEDLQKKSKEMVNAQQEQIKQEKTILQQTFMSEKEMLLKKEKQIEDEKKRLESQFEEEVRKSKALKDEQERQRKQMEDEKIKLKASMDAALIKQKEAEKEMFNKQKEMQELERKKLEQERMLAEENQQLREKLQQLEVAQKITQEIH-----IQTDCKKVLNGQSIEVDG--TQGYPGLSFDGIREKVPASRLFDIGLLSKVDYDRLQSGGTTVQELSKTDKLKTILRGNNCISGLLVHP-NQKMPIYQAIKEKKIAPGTGLVLLEAQAASGYIIDPIKNKKLSVNEAVKEGLIGPELHNKMLSAEKAVTGYKDPYTEAKISLFEALKKDLIGQDHAIRLLDAQIATGGIIDPINSHRVPNEIAYKQGQFDAATNKILQNPTDDMKGFYDPNTEENLTYSQLMKRCVADPETGLPLLPISEEAAQN-ARIFTDEETRDVFDKTTVSVPFGRFKGKTVTIWEIINSEYFTEDQKKDLIRQYKTGRITVEKIIRIVLTVAEEKEKKNEIAFDGLRSPVPAAKLLESKVIDKDLYNKLQKGQLLVKDVSEMEHVRNALKGTNCIAGVIVDSTKQTMSFYDAMKSDTMRPGPALHLLEAQAATGYIIDPIKNQKLTVDEAVKAGVVGPELHEKLLSAERAVTGYKDPFAGKTVSLFEAMKKDLILKDQGIRLLDAQLATGGIIDPVESHRVPHDVACMRGCFDDATQKFLSSATDEVKGYFDPNTQENVTYLQLYKRCVTDKKTGLKLLPLSEQAINAREEMKYTDAQTKDAMTQATVEVQSGPFKGRKVTIWELINSDYLTEEQRIDLIRQYRSGKMTIEKITKILIVIVTEKDAKKQEEGCFKGLRAPVPAKSLFDSKIIDKPTYDLLEQGKKTPKEVSKDNSVNKYLQGSESIAGVYLEPTKEKVSIYQAMKKKFLRQNTGIALLEAQAATGFIVDPSRNECLSVDDAVKAGIVGPELHEKLLSAEKAVTGYKDPFTGNKISLYQAMDKDLVLKEHAMPLLEAQLATGGIIDPVNSHRLPVETAIQRGYVSKQLASSIAES----KYFSDPASDENISYKQLKDKCITEPDTGLNLLKLSKPQAPTVVEKTYLYSEEQTQSDLSTTQIDLP---IEGQGSMSLWDVMNSNLLPEEQRAQLLEEYRSGNITKERMIIIIIEILEQREVIKGGNFQTGGTRRRQITIEDLYNARIIDLETFNMLKKEKKTMRDVMEMQSVKRYLYGTGSVAGVVTD-SNSKISIYQAMKREILKPEIAIGLLEAQAATGFIVDPVRNEMLTVDEAVRKGVVGPEFHDKLLSAERAVTGYKDPYSGKVISLFQAMKKGLVPEDYALRLLEAQTATGGIVDPEYNFHLPTEIATQRGYINKETNEKLS--DEVQGYVDPLTDEKMSYAQLLKRCKVDKD-GLHLLSLADRR-LLFRGLRKEITIEELIRSKIIDEQTVSELNEGRLTVEEVSNRLRKYLQGSSCISGVFVESTKDRLSIYQAMKKNMIRPGTAFELLEAQAATGYIIDPIKNLKLTVNEAVKMGIVGPEFKDKLLSAERAVTGYRDPYTGKMISLFQAMKKGLILRDHGIRLLEAQIATGGIIDPEESHRLPVEMAYNRGFFDEEMNEILNDPSDDTKGFFDPNTEENLTYLQLMERCIVDPDTGLVLLLLKEKKRERKTSSKSSVRKRRVVIVDPDSGKEMSVYEAYRKGLIDHQTYLELSEQECEWEEITMTSSEGVEKSILIDRRSGRQYDIDDAIAKGLIDQSAIDQYRSGTLSITEFADMLSGNMSGIRSRSSSFGSTSSYPMSPIPSIKTPASIWNDPTEETGPVAGILDTDSLEKVSVTEAIRRNVVDSITGQRLLEAQACTGGIIDPSTGEKFSVAEATEKGLIDKIMVDRLNLAQKAFHGFEDPRTKVKMSAAQALKKGWLYYEAGQRFLEVQYLTGGLIEPETEGRISLEEAIRKGAIDGRTAQKLRDVNAYTKYLTCPKTKLKISYKDAMDRSMVEEGSGIRLLEASSTSSKGLYSPYNVSGAASASGSRSGSRTGSRSGSRRGSFDATGSGFSMNFSSSSFTSSSYSRRF----------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:** *.****** ***:********:**:: **.:.** ****:*** **::** * ***** *********** :**:*****.****:.********* : :** : :**:::** . ** * : :* ::: **** : : :.*::.:* * *... ..** ********** ********** :***:.*********************::****: ****************:***********************************::* ****.***:**:******:******:**:*:******:*****:*******:*:* **** *******:***:***:***::***************:*********************..***.::***:****** :** :* **:***. ****:****:**:**** ******* ***.**:**.*** ::**:*.******:*:******:*******:*********: ** ****** **:**:*:***:*:***** *:::***:*:*** :** .*:: **********.********** ****** *.*************** :*::****** :...*. *:.:: :*.** ****:: **** :**********:*:* ****:***:**:*******:**:**:********* **.*****::*:**: **:*****:****:**:***.*:.*:.** **********:******.:***:**:** ***:.**.******::***::::* :****:::.**.: ***:* *.*******:********:*****:******:**:**: :*:*:*:::::** ***: *.********** :*:**:**:*..::.* ****:::*****.*: *.**::*: ****:**:*:*:****:* *:. :** :****. *..**.***:****** *:** *:*: *** ** * **::**.*:::**:** * :*:******.:. *:*:**:* * *:.*:**** **:* ::: *...*.: **:* . ::*:::**::**: * *:** *: *:::*::***:* **:*** *:* *:**:* *:* *: *:*:*.:.*::*: *.: ::* :**:**: .: * :**.*****::** *::*. .**:*********.:***.*****:*:: :*::*:*.::**:.: *:* :.**.:*.:** *:*.*: :..** *. *.:*: * * ***.*:*::*: : .* :**:**:** *:************ ***** * * *: **: ***:***:*: :.:: :*** **: ******:: :**:***::**:**::********::****:**::** **.*::*.*:.:***** ***:**** **********::* **:*:**: **: :****:::**::* *:**:*******:* *:** **:**: ***** :** .****::**:.** **:.*:: ** :*::*::*.* * :**::******::*****:* :*:. *: ** **::* *** :: ******:**:**::*:*:** ** ** : :** ****:**:**: *::*:::.:**** : *** *: **:::* ::**:**..****** **.***::**.:*:*:* :* **:***** :** **::***:**:***:*: ************** *::*:*** :*****:******::*.****.*::*:::******:**:*:*.****:*:**:*******: ::.*:**.***:** **: *.:** *:*::** **:***:****** *::**::* **:***** ******::*:**:***:***:****:*:*::***:********: :* ******.************************* *:***:**: **:**: ** ***::: **:*:*: **:*** :*::**:*:* ***** ** .****::** :*****.:::. *::* :*: ** ** : *:** ***.*******:::: ***:******:.* :****** *.:***: :* *::*: **: *:***:* : **::.::. ***:*:.* * .:*: * * *:* *:***:*: :**:*** *:*.*:*** :*:** :* :*:** **:***:** ** :***** ***:*** ** ** :***.*****:**:******:.::*:*:***:**.:*****:*** *. :*.:*::*******.**:***** *** *** **: ** :******:** ****:**::********: ***:**:*::** ***:***************:***::*:****:**:**:******:** **: * *:* ***:***::*****:***:::******:*:::::* **:***::*:**:***::*. :**.***:*:*::*:*:.***** .* ::*: **:***:**.** **:::*: ** **:** ..****: **. **::*:***: **::*: **:** :**. *::** *:: *::**:**::***:*: .* ***: * :*:***: : .**:*:*.**::: :**.:******:***:** ** :: : *. ..*.* . ** :. * :*:*:*.**.*.:* : *:** : :** .* *** **:: :.: *:* ..*:***::. *:*:.:* *::.: ::***.*:*********:::**::*::*:********::*****:*:****:********** :****:*::*.** ::*.:***:*******:***::***** ::**::* ** *::* :*:** ***:****.***** **::*** ****** ***::::**:. ::** *:****:*:***.***:*:*:************** :*::**::*::**:*******:*::**.**:*:*..:.*:***: ****:**:* **.:::*::**:*: *::*:* : **.**:*:. **** ::.: *.:*:*:*:: * : . *: ******.**:**** .. :*******:**:****:********:*****:**::*::****:*:**.** ::**:*******:****:** :***** *** ** :*. *.: *::. :.: * **.* * .** :* :** .*: ***.******:* .**:* *:: *::::: :: *** * **** :*:****.*:*:* *** :*:**:*:**:*:**: **:*.** * :: :**. .*.********..*: : ::.:. :: *::**.: *::*: .**.. **** .:**:*** :****:**:**:: :** .*. **********:*** **: * *.:*****:*******:***********:**::*..***:***.*.***::*.: *****:*********:***:**:.* ****..::: :*:. * * ** :.**::* ** ::*: :*:***.** * .: . ***.* :*:**:*: :. ****:* .* .:****:**:*:::**:***:*: ::::*.:************:*: *:*: .: : . **::* ***::****.***:*:::: .:.:*:.:* :*. ******:**** *...::****:*: :*..*:* **********::***:.* **********:****:**:***********:***: : ********* *:* : *****:** ********. .**** *:* ****:**:*:::** .**:.**** ***::**:***:**: *. * ** *:* * * ******:**:***:**:::** *. :*.** ::***::.*:*:*:*:***:****::**:***:******.:******************:*****.*****:***:**********************:***:**:*************:****************************:**:**:*********.****************************.**:*** ** **************************::**********************************::**:** **::***********.***:*.***:**:****:*************** .*:******.**:****:*. . :* : *.***************::*****:***::**:**.***********************:*.*::*.:***:*******:******* ********.**********************************:* **:.*:**:::*::*.*********.**:*****************:********:*:*****:: *:** ****.***:.*::***:*******:****************.*****::**.*.**: ", "identical_positions": 2907, "similar_positions": 1237, "identity": "48.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100920-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIR1-1", "uniprot_id": "RIMB2_RAT", "id": "Q9JIR1-1", "name": "RIMS-binding protein 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MREAAERRQQLELEHEQALAILNA----------------------------------------------------------------------------------------------KQQEIQLLQQ------------------------SKVRELEEKCRVQSEQ-----FNLLSRDLEKFRQHAGSIDLLGSNSVALLDVPLAPGKPFSQYMNG----LATSIHKGHEGPTGHYSVIGDYI---PLSGDK--------------LESPCVKPSFLLRS--SSPRCRFESEMDDD-RSSNKSKHSSS------------------------------------------------------------GKVHLCVARYSYNPFDGPNENP-------EAELPLTAGKYLYVYGDMD-EDGFYEGELLDGQRGLVPSNFVDFIQ----DNESRFAGTLGSEQDQNFLNHSGISLE-RDSILHLHSPTQVDSGITDNGGGTLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMSLALGRRTKALIEKLNTAACTYRISVQCVTSRGNSDELQCTLLVGKD-VVVAPSQLRVDNITQISAQLSWLPTNSNYSHIIFLNEEELDIVKAARYKYQFFNLRPNMAYKVKVLAQPHQMPWQLPLEQ-----------REKDEACVEFSTLPAGPPAPPQDVTVQAGATTASVQVSWKPPALTPTGLSNGANVTGYGVYAKGQRVAEVIAPTANGAAVELVRLRSLEAKAVSVRTLSAQGESMDSALAAIPPDLLVPP-----------------------------------------------------------APHPR--TAPPPKPLTSD--MDTKD--LGPHVKVDESWEQSRP---------------------------------------------------------PGP--------------------------AHGHMLEPPDMHSTGPGRRSPSPSRILPQPQGAPVSTTVAKAMAREAAQRVAE-TSKLEKRSLFLEQSSAGPYANSDEEDGYASPEVKRRGTSVDDFLKGSELGQQPHCCHGDEYHTESSRGSDLSDIMEEDEE-ELYSEMQLEDGGRRRPSGTSHNALKILGNSALMGRGDRMEHVSRRYSHSGGGPQRHRP-MAPSIDEYT--------------------------------GRDHLSPDFYDESETDP----GAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIHADDEEMMDQLLRQGFLP-----------------------LNTPVEKIERSRRSGRGHSVPTRRMVALYDYDPRESSPNVD-VEAELLFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVHLS---------------------DAPPHYSHD-----PPMRTKAKR---VSQPP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80U40-1", "uniprot_id": "RIMB2_MOUSE", "id": "Q80U40-1", "name": "RIMS-binding protein 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MREAAERRQQLELEHEQALAFLNA----------------------------------------------------------------------------------------------KQQEIQLLQQAQVEAKKEHEGAVQLLE-------SKVRELEEKCRVQSEQ-----FNLLSRDLEKFRQHTGSIDLLGSSSVALLDVPLAPGKPFPQYMNG----LATSIHKGHEGPTGHYSVIGDYI---PLSGDK--------------LESPCVKPSFLLRS--SSPRCRFESEMDND-RNSNNSKQSSS------------------------------------------------------------GKVHLCVARYSYNPFDGPNENP-------EAELPLTAGKYLYVYGDMD-EDGFYEGELLDGQRGLVPSNFVDFIQ----DNESRLAGTLGSEQDQNFLNHSGISLE-RDSILHLHSPTQVDSGITDNGGGTLDVNIDDIGEDTVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMSLALGRRTKALIEKLNTAACTYRISVQCVTSRGNSDELQCTLLVGKD-VVVAPSQLRVDNITQISAQLSWLPTNSNYSHIIFLNEEELDIVKAARYKYQFFNLRPNMAYKVKVLAQPHQMPWQLPLEQ-----------REKKEACVEFSTLPAGPPAPPQDVTVHAGATAASVQVSWKPPALTPTGLSNGANVTGYGVYAKGQRVAEVIAPTADGTAVELIRLRSLEAKAVSVRTLSVQGESMDSALAAIPPDLLVPP-----------------------------------------------------------APHPR--TAPPPKPLASD--MDTKDQHLGPHVKVDESWEQSRS---------------------------------------------------------PGP--------------------------AHGHMLEPPDMHSAGPGRRSPSPSRILPQPQGAPVSTTVAKAMAREAAQRVAE-SNRLEKRSLFLEQSSAGQYTNSDEEDGYASPEVKRRGTSVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEE-ELYSEMQLEDGGRRRPSGTSHNALKILGNSTLMGRADRMEHVSRRYSHSGGGSHRHRPAMAPSIDEYT--------------------------------GRDHLSPDFYDESETDP----GAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIHADDEEMMDQLLRQGFLP-----------------------LNTPVEKIERSRRSGRGHSVPTRRMVALYDYDPRESSPNVD-VEAELPFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVHLS---------------------DAPPHYSHD-----PPMRSKAKRKKSVHFTP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15034-1", "uniprot_id": "RIMB2_HUMAN", "id": "O15034-1", "name": "RIMS-binding protein 2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MREAAERRQQLQLEHDQALAVLSA----------------------------------------------------------------------------------------------KQQEIDLLQK------------------------SKVRELEEKCRTQSEQ-----FNLLSRDLEKFRQHAGKIDLLGGSAVAPLDISTAPSKPFPQFMNG----LATSLGKGQESAIGGSSAIGEYIRPLPQPGDR--------------PEPLSAKPTFLSRS--GSARCRSESDMENE-RNSNTSKQRYS------------------------------------------------------------GKVHLCVARYSYNPFDGPNENP-------EAELPLTAGKYLYVYGDMD-EDGFYEGELLDGQRGLVPSNFVDFVQ----DNESRLASTLGNEQDQNFINHSGIGLE-GEHILDLHSPTHIDAGITDNSAGTLDVNIDDIGEDIVPYPRKITLIKQLAKSVIVGWEPPAVPPGWGTVSSYNVLVDKETRMNLTLGSRTKALIEKLNMAACTYRISVQCVTSRGSSDELQCTLLVGKD-VVVAPSHLRVDNITQISAQLSWLPTNSNYSHVIFLNEEEFDIVKAARYKYQFFNLRPNMAYKVKVLAKPHQMPWQLPLEQ-----------REKKEAFVEFSTLPAGPPAPPQDVTVQAGVTPATIRVSWRPPVLTPTGLSNGANVTGYGVYAKGQRVAEVIFPTADSTAVELVRLRSLEAKGVTVRTLSAQGESVDSAVAAVPPELLVPP-----------------------------------------------------------TPHPR--PAPQSKPLASSGVPETKDEHLGPHARMDEAWEQSRA---------------------------------------------------------PGP--------------------------VHGHMLEPP----VGPGRRSPSPSRILPQPQGTPVSTTVAKAMAREAAQRVAE-SSRLEKRSVFLERSSAGQYAASDEEDAYDSPDFKRRGASVDDFLKGSELGKQPHCCHGDEYHTESSRGSDLSDIMEEDEE-ELYSEMQLEDGGRRRPSGTSHNALKILGNPASAG---RVDHMGRRFPRGSAGPQRSRPVTVPSIDDY---------------------------------GRDRLSPDFYEESETDP----GAEELPARIFVALFDYDPLTMSPNPDAAEEELPFKEGQIIKVYGDKDADGFYRGETCARLGLIPCNMVSEIQADDEEMMDQLLRQGFLP-----------------------LNTPVEKIERSRRSGRRHSVSTRRMVALYDYDPRESSPNVD-VEAELTFCTGDIITVFGEIDEDGFYYGELNGQKGLVPSNFLEEVPDDVEVYLS---------------------DAPSHYSQD-----TPMRSKAKRKKSVHFTP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IAH9-1", "uniprot_id": "A0AC58IAH9_DANRE", "id": "A0AC58IAH9-1", "name": "RIMS-binding protein 2", "aln": "---------------MRGERTDIELLLKQSQTELLWIQRQLAIIAARDASHARAKKKLKQEAQPLH--LASHTAHHVNRCRLLEDKNRALKLELAALRQLKQQHRFLESEVNERRKRCQVLEREVKNKTLACKTLKNELQDALLERKRLN----------------------------RELLSHILKATEYEKVKSDYEQLKKAFGCVSQERDLARQEKAQLQDKLENLEQVLKHMREAADRRQQLEAEHEQALAFLNS----------------------------------------------------------------------------------------------RQQEINLLQKVQAEAEKEREEVVHLLESHMDKMQVKVHDLEQKCRAQSEQ-----CNILSKELEKYHLGSDAEDTLNTD---------SQEKNLCNSYNS----LQRQAEKSDERSDG-SPLVSELPIVQQHKRDK--------------PEQLTVKPTVQTRSRSSSPMQASLSEMDDEVRPPSRSKTRYT------------------------------------------------------------GQVRLCTARYSYNPYDGPNEHP-------EAELPLVAGKYLYVYGNMD-DDGFYEGELLDGQRGLVPSNFVEFVQ----DKEK---LSIEGVEEQGRLEQSCLSLTTIDGGGPLDSISSDVLGHCSNGTGALDG--EELGEDIVPYPRKINLIKQLARSVIVAWEAPMVPLGWGNINGYNILVEGEVRSSVPFGGRTKLLLEKLDLAAFTYRVSVQSVTDRGLSDELRCTLLVGRN-VVVAPTGLRMDDILRDSAELSWLPSNSNYAHVVYLDGVEHAVVKPCSYKLRFVNLKAATVYKVKVLAKPHQVPWHMPLEQ-----------REKREAGVEFCTQAAGPPLPPQEVQVQCGHAPGILQVRWKPPAMSPIGMSNGANIIGYAVCTKGQRIAEVLYPMADYVAVELNRLQCLEAREVIVRTLSAQGESQDSHVAVIPNHLLVPLSKTLPLPHRMQPPLPTQQSHTMPHHPQILPRHTGPQPPTHLQPLPICPNQPPAHLHPHRMPHPTQPSPPHLQPLLAHPIPQPQPSIPMPQPQSSMPMPQSQPPMPMPQPQQPMTMPQPQPPIPMLQPQPAIPMPQPHIPQLPLPQPQRPLSARELETKEPGPGMLHHGGGPPQPWEPGCSPSGIPTGMPHGHTLEAP----ACPNRRSPSPQRILPQPRGTLIPDTVAKAIAREAAQRVAAESGRMERRSQGFHSQ------NSDEEEDEESYQARRRGASVDDFLRGSELGRQPHYSHSEEYHTESSRGSDLSDIMEEDEE-ELYSEMQHEEGRRR----NSHNALKTGGSTLSSG---QLDRDSYRKAPHRGPQPQRRPLTVPSIEITTESNSEGNLSPVKEDVYYGSVARHRTWSSRRHGGRRPPYDGYRDRSRRSPPYYDESEQEDFRIFVALFDYDPLSMSPNPDAADEELPFKEGQIIKVYGDKDNDGFYRGEIRGRSGLIPCNMVSEIRAEDDETMEQLMKQGFLP-----------------------LNTPVDRIEQNRRG--RHPVATRRMVALYDYDPRESSPNVD-VEAELTFCAGDIVAVFGDIDEDGFYYGELNGHRGLVPSNFLEEVPDDVEVYLT---------------------DTPSHHGQDESNPAPAARPEAKRVPVESTVPAPALGRPASPTVRPLLPVGPVRPLSPARGPRDLASKKKKGLLSKGKKLLKKFSK-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4JDC9-1", "uniprot_id": "A0A0B4JDC9_DROME", "id": "A0A0B4JDC9-1", "name": "", "aln": "MHLCEFPSANVEEENRRPEKAAAAASKKQKHKQQKSRPRGSHSMPYESMHHHQSAAAAVAAGTTPNGMLDALSLQLRDAEMRRTEIERAHQETLAQIRNLSGSARPDAEAVENLQSRARELEKKVALENVRCEELQIELTSALKAKQASRSACSGMGSVSSGGGATIPTSASSSTVTWAPTISHQDQGSEIDIIMAKIEQDNRVLAELEQPRTSASASMSALP-PSSMLSTVNSEFRTISKSELEEELNRYKRAVLGGSGGGGGGVGGGGGGVSALSSGYSSLPQSLASTLPNGGASTSLSGTSLGSHSAAAAAAAHSVSAGSGGVVGGGGQGGLSSISALVPNSISGISSSLSSHAIQSMQYGTGQTSVEKLLSGTSGITGIPPLPVNIHTMKAMPTALSQRGTIQLYNLQSTTMPLLSLNSHNLPPAGSTSYSALGAGGGTSLTHPTMANLGLLDTGTLLGSTGLSGLGVGPSVGGITGATSLYGLSGGGGGAGGLGSSYGPPFLDVASSASYPFTAAALRQASKMKMLDEIDIPLTRYNRSSPCSPIPPNNWGLDEFTDGLSVSMMHNRGGLALGALDLDTRNHGLNGASEPQVDMLDIPGKGRCCVFIARFPYDPPDVHNEFLSMPCREAEGELSLCAGDYLLVWTSGEPQGGYLDAELLDGRRGLVPASFVQRLVGDDLLEFHQAVLSTLRDAEDGSMQCDTTSLPSLPPHNPLLTHTHEDLARLSETHTDLEHDQDDISDN-VPAPKHLTLERQLNKSVLIGWS-PPEPVGYNLIDSYHVYVDGVLKVTVKANERTRALIEGVDSTRPHRISVRSVTQNRQTSRDAACTMIIGRDTAHLGPSAVRASHITCSSAVISWLPANSNHQHVVCVNNVEVRTVKPGMYRHTITGLAPSTQYRVTVRAKHLRAVGQHAANVGQTGGAGRPGQEEAPGAYADFRTLTKGLPDPPQEIQLEAGPQDGTILVTWQPVNRP----TSTGPVTGYAVYADGKKVTDINSPTGDHALIDIGKLGVFNPRAVTIRTKSRDSQSADSAPILIPNTVRNAVAR--------------------------------------------------------RGPNQMGMGPQLPQGPHGMTVQQQMGGMPGQPGQQGQHMMGGQQ---------------------------------------------------------------------------------------DHGQYDPNQMQQQQQQQGQPGQPGHQPDAGSGLLGGLLGGLFSKPTQNQVNQ--NGYQPGQPGAQRGMVPIPGRPQGPQQQQQQPYGPQGPMGGPRFRGPVPGQLNMQGQQMQGQMQGQMQGQMQGQMSGQMPGQMPGQMPGQMPGQMAGQMAGQMPGQMPGQMPGQMSGQMPGQMMGPRGPLNQQQQQQQQMQQGQMMPGQQ------------------------------AGQQQAQPGQPGQPGQMP-----GAQKKPRYFVAMFDYDPSTMSPNPDGCDEELPFQEGDTIKVFGDKDADGFYWGELRGRRGYVPHNMVSEVEDTTASMTAGGQMPGQMPGQMGQGQGVGVGGTAQVMPGQGAPQQSMRNVSRDRWGDIYANMPVKRMIALYDYDPQELSPNVDAEQVELCFKTGEIILVYGDMDEDGFYMGELDGVRGLVPSNFLADAPDQYNNQMGPGGVAGRGGLSQRGRGQGPGARGPPPPPRDNMMPGMGGRGQPGKNARPASPTLLDNTGHPAPDHQTQGMIGRVGNVGLQQQQQQQQQQQQLQQQQQYGQQQTQMGQQQQQQQQMGQPGMMGQQMGQPMGQQMGQMGQMGQMGQQQMGQQQMGQQQQPPTTQAQTGGLFSGATSLLSGATSAATGGLFGSKQPPKTDPMQPQGGVQPAQQQANAFGAQQPGMGMQQQGGMQSGMQQGMQQGMQQGMQQGMQQGMQQGMQQGMQQGMQPGMQQQQQQPQQVPPQAQAPPPGPGAGLLGGLKGIAAAAPGGDVLSKGKDLFGKFGFGFGK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :. . : : :: : .. .: .: *: :* ::: :: . *:: *: * : : . . * . * . :. . .: .: .* :: . : *: : **:.*:* * ** *.**.* **.** *: . : :.*: :.*****:*****:.**: : : : ::. :: . .* * : : . .: *: :::.:: ** *:::.* :** :**::.*. * * *:. :..*:: *: : .: . **: *:* :: : . . .* * : **:::*:: . :.*: :* ..* ** :****:***: *:: :: * **. *: : .* . *:*.* *: : : . : .* * .:* * . * * ***:: :..* . : * *:* . :. . : **.* :.*:::::: * .: . ::: :* ::.: * :** * :.:* ** :* : . *: . : . : : . .: . :. : .*. *:. . : :. ::: : ::* . : . . .: : . :*. . ::*. *: : : : :.. .::.. *. : :: .:* : : .: . : *. : : : .: *: . .. * . : * ***:***** :******..:*****:**: ***:**** **** ** .* * :* *****:. . * :* : .: .:.:.* . :..:**:*******:* ***** :.** * :*:*: *:*::****** ***:* :******** :.**: : : *. :* * :. : . ", "identical_positions": 217, "similar_positions": 319, "identity": "10.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100920-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q05193-1", "uniprot_id": "DYN1_HUMAN", "id": "Q05193-1", "name": "Dynamin-1", "aln": "MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSDLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSG-DQIDTYELSGGARINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKIREPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSS--KHIFALFNTEQRNVYKDYRQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASET-EENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFG--------PPPQVPSRPNRAPPGVPSRSGQ---ASPSRPESPRPPFDL-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P21575-1", "uniprot_id": "DYN1_RAT", "id": "P21575-1", "name": "Dynamin-1", "aln": "MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVNSTTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSDLANSDALKIAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQLLSIEKEVDEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSG-DQIDTYELSGGARINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDLAFEATVKKQVQKLKEPSIKCVDMVVSELTSTIRKCSEKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSS--KHIFALFNTEQRNVYKDYRQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASET-EENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFG--------PPPQVPSRPNRAPPGVPSRSGQ---ASPSRPESPRPPFDL-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P39053-1", "uniprot_id": "DYN1_MOUSE", "id": "P39053-1", "name": "Dynamin-1", "aln": "MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIVTRRPLVLQLVNSTTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPINLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSDLANSDALKIAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQKDIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKLQSQLLSIEKEVDEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSG-DQIDTYELSGGARINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKIREPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSS--KHIFALFNTEQRNVYKDYRQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASET-EENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFG--------PPPQVPSRPNRAPPGVPSLGAWRLNSPQGKHENRAGKARL-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2BCV1-1", "uniprot_id": "A0A8M2BCV1_DANRE", "id": "A0A8M2BCV1-1", "name": "Dynamin-2", "aln": "MGNRGMEDLIPLVNRMQDAFSAIGQNANLDLPQIAVVGGQSAGKSSVLENFVGKDFLPRGSGIVTRRPLVLQLINCPTEYAEFLHCKGKKFTDFDEVRQEIEAETDRITGQNKGISPVPINLRVYSPNVLNLTLVDLPGMTKVPVGDQPADIEAQIRDMLMQFVTKENCLLLAVSPANSDLANSDALKIAKEVDPQGMRTIGVITKLDLMDEGTDAREILENKLLPLRRGYIGVVNRSQKDIDGKKDITAAMSAERKFFLTHPSYRHLADRMGTPYLQKALNQQLTNHIRDTLPGLRNKLQSQLLSIEKEVEEYKHFRPDDPSRKTKALLQMVQQFAVDFEKCIEGSG-DQVDTVELSGGARINRIFHERFPFELVKMEFDEKELRKEISYAIKNIHGIRTGLFTPDMAFETIVKRQIAKIKEPCQKCVDLVITELVNTVRQCTKKLAQYPMLREEMERIVTQHIRDRESRTKNQVMLLIDIELAYMNTNHEDFIGFANAQQRSSQMNKKKAAGNQDEIMVIRKGWLTINNIGIMKGGAKEYWFVMTAENLSWYKDDEEKEKKYMLPLDNLKLRDIEKSFMSS--KHVFALFNTEQRNVYKDYRQLELASDTQEEVDSWKASFLRAGVYPERITDKEKQSDTSDESSSDGFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKDFIHAELLANLYSCGDQNTLMEESAEQAQHREEMLRMYHALKEALNIIGDISTSTVSTAMPPPVDDSWLQVQGGPSGRRSPMSSPTPQRRAPPGPP-RPGGR-TAPGPPTIG-----APPVPSRPGASPDPFGA-------PPPQVPSRPNRAPPGVPSRPSK---GSPSHSESPQPSFDS-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P27619-1", "uniprot_id": "DYN_DROME", "id": "P27619-1", "name": "Dynamin", "aln": "-----MDSLITIVNKLQDAFTSLGVHMQLDLPQIAVVGGQSAGKSSVLENFVGKDFLPRGSGIVTRRPLILQLINGVTEYGEFLHIKGKKFSSFDEIRKEIEDETDRVTGSNKGISNIPINLRVYSPHVLNLTLIDLPGLTKVAIGDQPVDIEQQIKQMIFQFIRKETCLILAVTPANTDLANSDALKLAKEVDPQGVRTIGVITKLDLMDEGTDARDILENKLLPLRRGYIGVVNRSQKDIEGRKDIHQALAAERKFFLSHPSYRHMADRLGTPYLQRVLNQQLTNHIRDTLPGLRDKLQKQMLTLEKEVEEFKHFQPGDASIKTKAMLQMIQQLQSDFERTIEGSGSALVNTNELSGGAKINRIFHERLRFEIVKMACDEKELRREISFAIRNIHGIRVGLFTPDMAFEAIVKRQIALLKEPVIKCVDLVVQELSVVVRMCTAKMSRYPRLREETERIITTHVRQREHSCKEQILLLIDFELAYMNTNHEDFIGFANAQNKSENAN--KTGTRQLGNQVIRKGHMVIQNLGIMKGGSRPYWFVLTSESISWYKDEDEKEKKFMLPLDGLKLRDIEQGFMSMSRRVTFALFSPDGRNVYKDYKQLELSCETVEDVESWKASFLRAGVYPEKQETQENGDESASEESSS------DPQLERQVETIRNLVDSYMKIVTKTTRDMVPKAIMMLIINNAKDFINGELLAHLYASGDQAQMMEESAESATRREEMLRMYRACKDALQIIGDVSMATVSSPLPPPVKNDWLPS-GLDNPRLSPPS-PGGVRGKPGPPAQSSLGGRNPPLPPSTGRP---APAIPNRPGGGAPPLPGGRPGGSLPPPMLPSRVSGAVGGAIVQQSG---ANRYVPESMRGQVNQAVGQAAINELSNAFSSRFK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:.**.:**::****:::* : :*************************:***************:***:* ***.**** *****:.*:*:* *** ****:** ***** :*********:******:****:***.:**** *** **::*::**: **.**:***:***:*********:******** *******************::***********************:*:*** *::*******:******:***:******:.*****************:***.*:*::****:*:*:*:*.*.: ****:***:**: ***: ***** ::* ******:********: **:*** ******:***:**:******.******:***: **:*: ::** ****:*: ** .:* *: *: :** **** ***:* *:*:** *:*::****:*******************::*.: * *:. .* ***** :.*:*:******:: ****:*:*.:*****::*****:**.:*.*****:*:.*** : ****..: *******:****:.:* *:*:**************: :*: .:: .*..*. ******************* **.**.**::**:** *:***:*:** .****:**:.*** :******.* :*:******:* *:**.****:. :***:.:****.:.** . * ** * * * * *. . . .* **. * **.:*.***... *: *** :*** . * *. . . *. ", "identical_positions": 545, "similar_positions": 185, "identity": "60.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100920-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9P2G1-1", "uniprot_id": "AKIB1_HUMAN", "id": "Q9P2G1-1", "name": "Ankyrin repeat and IBR domain-containing protein 1", "aln": "MGNTTTKFRKALINGDENLACQIYENNPQLKESLDPNTSYGEPYQHNTPLHYAARHGMNKILGTFL-GRDGNPNKRNVHNETSMHLLCMGPQIMISEGALHPRLARPTEDDFRRADCLQMILKWKGAKLDQGEYERAAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENKDTPCDCAEKQHHKDLALNLESQMVFSRDPEAEEIEAEYAALDKREPYEGLRPQDLRRLKDMLIVETADMLQAPLFTAEALLRAHDWDREKLLEAWMSNPENCCQRSGVQMPTPPPSGYNAWDTLPSPRTPRTTRSSVTSPDEISLSPGDLDTSLCDICMCSISVFEDPVDMPCGHDFCRGCWESFLNLKIQEGEAHNIFCPAYDCFQLVPVDIIESVVSKEMDKRYLQFDIKAFVENNPAIKWCPTPGCDRAVRLTKQGSNTSGSDTLSFPLLRAPAVDCGKGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAANCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKCKYDFCWICLEEWKKHSSSTGGYYRCTRYEVIQHVEEQSKEMTVEAEKKHKRFQELDRFMHYYTRFKNHEHSYQLEQRLLKTAKEKMEQLSRALKETEGGCPDTTFIEDAVHVLLKTRRILKCSYPYGFFLEPKSTKKEIFELMQTDLEMVTEDLAQKVNRPYLRTPRHKIIKAACLVQQKRQEFLASVARGVAPADSPEAPRRSFAGGTWDWEYLGFASPEEYAEFQYRRRHRQ-RRRGDVHSLLSNPPDPDEPSESTLDIPEGGSSSRRPGTSVVSSASMSVLHSSSLRDYTPASRSENQDSLQALSSLDEDDPNILLAIQLSLQESGLALD---EETRDFLSNEASLGAIGTSLPSRLDSVPRNTDSPRAALSSSELLELGDSLMRLG---AENDPFSTDTLSSHPLSEARSDFCPSSSDPDSAGQDPNINDNLLGNIMAWFHDMNPQSIALIPP-ATTEISADSQLPCIKDGSEGVKDVELVLPEDSMF--EDASVSEGRGTQIEENPLEEN---ILAGEAASQAGDS-GNEAANRGDGSDVSS---QTPQTSSDWLEQVHLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZPS6-1", "uniprot_id": "AKIB1_MOUSE", "id": "Q6ZPS6-1", "name": "Ankyrin repeat and IBR domain-containing protein 1", "aln": "MGNTTTKFRKALINGDENLACQIYENNPQLKESLDPNISYGEPYQHNTPLHYAARHGMNRILGTFLFGRDGNPNKRNVHNETSMHLLCMGPQIMISEGTLHPRLARPVEDDFRRADCLQMILQWKGAKLDQGEYERAAIDAVDNKKNTPLHYAAASGMKACVELLVKHGGDLFAENENRDTPCDCAEKQQHKDLALSLESQMVFSRDPEAEEIEAEYAALDKREPYEGLRPQDLRRLKDMLIVETADMLQAPLFTAEALLRAHDWDREKLLEAWMSNPENCCQRSGVQMPTPPPSGYNAWDTLPSPRTPRTTRSSVTSPDEISLSPGDLDTSLCDICMCSISVFEDPVDMPCGHDFCRGCWEAFLNLKIQEGEAHNIFCPAYECFQLVPVDVIESVVSKEMDKRYLQFDIKAFVENNPAIKWCPTAGCERAVRLTKQGSNPSGSDTLSFPLLRAPAVDCGKGHLFCWECLGEAHEPCDCQTWKNWLQKITEMKPEELVGVSEAYEDAANCLWLLTNSKPCANCKSPIQKNEGCNHMQCAKCKYDFCWICLEEWKKHSSSTGGYYRCTRYEVIQHVEEQSKEMTVEAEKKHKRFQELDRFMHYYTRYKNHEHSYQLEQRLLKTAKEKMEQLSRALKETEGGCPDTTFIEDAVHVLLKTRRILKCSYPYGFFLEPKSTKKEIFELMQTDLEMVTEDLAQKVNRPYLRTPRHKIIRAACLVQQKRQEFLASVARGVAPADSPDAPRRSFAGGTWDWEYLGFASP------EYRRRHRQQRRRGDVHSLLSNPTDLDEPSESTFDLPEG-SSGRRPGASVVSSASMSVLHSSSLRDYSPASRSANQDSLQALSSLDEDDPNILLAIQLSLQESGLDMD---EETRDFLSNETSLGAIGSSLPSRLDSVPRSTESPRAALSSSELLELGDSLMRLG---ADSDPFSTDTLSSRPLSETRSDFCPSSSDLDSAGQDPSANDNLLGNIMAWFHDMNPQSIALIPPAATTEISAEPQLPCIRDGSEGVRDMELVPPEDSVS--KDTGVHEGERAQMEENPLEEN---ILAREELSQAGDS-SNEAVGRGDRPDAAS---QTPQTSSDWLEQVHSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32TBI7-1", "uniprot_id": "A0AB32TBI7_DANRE", "id": "A0AB32TBI7-1", "name": "Ankyrin repeat and IBR domain-containing protein 1", "aln": "MGNTATKFRKALISGDEVLAYQLYEGNPQFKESLDPNTSYGEPYQHNTPLHYAARHAMTRILRSFLFSKDGNPNKRNVHNETALHVLCMGPLILLSEGALQPRLARPYEDERRRAECLQMILKWTGAKLDRGKYESADVSATDNKKNTPLHYAAASGMKTCVEFLVKRGADLFAENENKETPCDCAERQHHKELALGLESQMVFSTDPNAEDIEAEYAALDRREFYEGLRVQDLRRLKDMLIVETADMLQAPLFTAEALLRAHDWDREKLLEAWMSNAEDCCQRSGVQMPIPPPRGYNTWDTLPSPRTPRTTRSSITSPDEISLTPADDDHSLCGICMCAASMFEEPVDIPCGHEFCRGCWESFLNLKIQEGEAHNIFCPAYDCFQLVPVEVIESIVSKEMDKRYLQFDIKAFVENNPAIRWCPRAGCDRAVRLAGQGPGASTSDPLSFPRLQAPAVDCGKGHLFCWECQGEAHEPCDCQTWKMWLQKVTDMKPEELAGVSEAYEDAANCLWLLTNSKSCANCKSPIQKNEGCNHMQCAKCKYDFCWICLEEWKKHSSSTGGYYRCTRYEVIQQVEEQSKEMTVEAEKKHKNFQELDRFMHYYTRFKNHEHSYQLEERLLKTAKDKMEQLSKVLSGREGGPPDTTFIEDAVHELLKTRRILKCSYPYGFFLEPKSTKKEIFELMQTDLEMVTEDLAQKVNRPYLRTPRHKIIRAACLVQQKRQEFLASVARGVAPNDSPEAPRRSFAGGTWDWEYLGFASP------EIQRNHAFLGGIDPREHCQYTGSHPQEYAEFQYRRRHR-QRRRGDMASLRSNTPDPDDPGHSTLDTQEIGGGQRPGLPMPHSSLDEDDPNILLAIQLSLQESGLMAGGAGVDAQEILSNEASLGAIGTSLPTRLDPVLCGIDVPRAALSSSELLEVGDSLKKLGNISGQNVPLRFDNLNNPARDPSEGPFHNPARHMESSDFN-SDNANLLGNIMAWFHDMNPQNISLVPSAGAMHQEFASQSARMPSESDCAVPQWITGGDREVEREFDSGIIAGEREPVRPTQLDLIGLDMCPPPSTVELGETPSALNPCHSDTPKCDSDPDQPSSSSSEWEGQVHLV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:********.*** ** *:**.***:******* ******************.*.:** :** .:*************::*:***** *::***:*:****** **: ***:******:*.*****:*:** * :.*.*****************:***:***:*.********::*******:*:**:***.******** **:**:*********:** ***** **********************************************.*:********** *** ***:****************:********:*.* * ***.****: *:**:***:****:*******:*******************:*******::***:************************:*** .**:*****: **...* **.**** *:**************** ************* ****:*:******.********************.******************************************************:*****************.*************:**********:*******:******:.*. *** *********** ***********************************************************:********************** ***:********************* : :*.* . . . .. :* :* . . * :*: *.:. . . * * . . . . . *********************** . :::::****:******:***:***.* . : ************:**** :** .:. *: *.*.. . . :.. * .: . :*:. : . * ****************.*:*:*. .: . . .* . : . *: . :. : .: *:.: *. :. . *: : . : *:: . :.* .. * *...:**:* *** *", "identical_positions": 760, "similar_positions": 180, "identity": "68.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6URW6-1", "uniprot_id": "MYH14_MOUSE", "id": "Q6URW6-1", "name": "Myosin-14", "aln": "-MAAVTMSVSGRKVASRPGPVPEAAQSFLYAPRTPNVGG-PGG-----------------------------PQVEWTARRMVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK------------RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPK----GRKE---------------------------------PGVPASVSTMSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDIAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEP--CSHYRFLTNGPS-SSPGQ-ERELFQETLESLRVLGLLPEEITAMLRTVSAVLQFGNIVLKKERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGSHPKFQRPRNLRDQADFSVLHYAGKVDYKASEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD-----------------------------------------VEGIVGLEQVSSLGD------GPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMD------GKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQRRQQQQSALRVMQRNCAAYLKLRN-WQWWRLFIKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERTRLAEQLRAEAELCSEAEETRARLAARKQELELVVTELEARVGEEEECSRQLQSEKKRLQQHIQELESHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERRLLEERLAEFSSQAAEEEEKVKSLNKLRLKYEATISDMEDRLKKEEKGRQELEKLKRRLDGESSELQEQMVEQKQRAEELLAQLGRKEDELQAALLRAEEEGGARAQLLKSLREAQAGLAEAQEDLEAERVARAKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKALEEESRAHEVSMQELRQRHSQALVEMAEQLEQARRGKGVWEKTRLSLEAEVSELKAELSSLQTSRQEGEQKRRRLESQLQEVQGRSSDSERARSEAAEKLQRAQAELESVSTALSEAESKAIRLGKELSSAESQLHDTQELLQEETRAKLALGSRVRALEAEAAGLREQMEEEVVARERAGRELQSTQAQLSEWRRRQEEEAAVLEAGEEARRRAAREAETLTQRLAEKTEAVERLERARRRLQQELDDATVDLGQQKQLLSTLEKKQRKFDQLLAEEKAAVLRAVEDRERIEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKNVHELERARKAAEQAASDLRTQVTELEDELTAAEDAKLRLEVTVQALKAQHERDLQGRDDAGEERRRQLAKQLRDAEVERDEERKQRALAMAARKKLELELEELKAQTSAAGQGKEEAVKQLKKMQVQMKELWREVEETRSSRDEMFTLSRENEKKLKGLEAEVLRLQEELAASDRARRQAQQDRDEMAEEVASGNLSKAATLEEKRQLEGRLSQLEEELEEEQNNSELLKDHYRKLVLQVESLTTELSAERSFSAKAESGRQQLERQIQELRARLGEEDAGARARQKMLIAALESKLAQAEEQLEQESRERILSGKLVRRAEKRLKEVVLQVDEERRVADQVRDQLEKSNLRLKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL---------RRGPLTFTTRTVRQVFR--LEEGVASDEEEAEGAEPGSAPGQEPE------APPPATPQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A9A3-1", "uniprot_id": "A0A8I6A9A3_RAT", "id": "A0A8I6A9A3-1", "name": "", "aln": "-MATVTLSVPGRKVASRPGPVPEAAQPFLFAPRTPNVGG-PGG-----------------------------PQVEWTARRMVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK------------RHEVPPHIYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPK----GRKE---------------------------------PGVPASVSTMSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDIAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEP--YSHYRFLTNGPS-SSPGQ-ERELFQETLESLRVLGLLPEEITAMLRTVSAVLQFGNIVLKKERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGSHPKFQRPRNLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKDEQGGLQQFTFLGSFPSPSPGPAGGLSSGASPPGLGSLCAPTVEGIVGLEQVSSLGD------GPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMD------GKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQRRQQQQSALRVMQRNCAAYLKLRN-WQWWRLFIKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCSEAEETRARLAARKQELELVVTELEARVGEEEECSRQLQSEKKRLQQHIQELETHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERRLLEERLAEFSSQAAEEEEKVKSLNKLRVKYEATIADMEDRLKKEEKGRQELEKLKRRLDGESSELQEQMMEQKQRAEELLIQLGRKEEELQSALVRAEEEGGARAQLLKSLREAQAGLAEAQEDLEAERVARAKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEEARTHEVAMQELRQRHSQALVELTEQLEQARRGKSVWEKTRLSLEAEVSELKTELSSLQTSRQEGEQKRRRLESQLQEVQGRSSDSERARAEAAEKLQRAQVELESVSTALSEAESKAIRLSKELSSAESQLHDTQELLQEETRAKLALGSRVRALEAEAAGLREQMEEEVVARERAGRELQTTQAQLSEWRRRQEEEAAVLEAGEEARRRAAREAETLAQRLAEKTEAVERLERARRRLQQELDDATVDLGQQKQLLSTLEKKQRKFDQLLAEEKAAVLRAVEDRERVEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKNVHELERARRVAEQAASDLRTQVTELEDELTAAEDAKLRLEVTVQALKAQHERDLQGRDDAGEERRRQLAKQLRDAEVERDEERKQRALAMAARKKLELELEELKAQTSAAGQGKEEAVKQLKKMQAQMKELWREVEETRSSREEMFTLSRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMAEEVASGNLSKAATLEEKRQLEGRLGQLEEELEEEQNNSELLKDHYRKLVLQVETLTTELSAERSFSAKAESGRQQLERQIQELRARLGEEDAGARARQKMLIAALESKLAQAEEQLEQESRERILSGKLVRRAEKRLKEVVLQVDEERRVADQLRDQLEKSNLRLKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL---------RRGPLTFTTRTVRQVFR--LEEGVASDEEEAEGAEPGSAPTQEPE------APPPAAPQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7Z406-1", "uniprot_id": "MYH14_HUMAN", "id": "Q7Z406-1", "name": "Myosin-14", "aln": "-MAAVTMSVPGRKAPPRPGPVPEAAQPFLFTPRGPSAGGGPGSGT--------------------------SPQVEWTARRLVWVPSELHGFEAAALRDEGEEEAEVELAESGRRLRLPRDQIQRMNPPKFSKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRGKK------------RHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPK----GRKE---------------------------------PGVP--------GELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEP--CSHYRFLTNGPS-SSPGQ-ERELFQETLESLRVLGFSHEEIISMLRMVSAVLQFGNIALKRERNTDQATMPDNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQADFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPPGLLALLDEECWFPKATDKSFVEKVAQEQGGHPKFQRPRHLRDQADFSVLHYAGKVDYKANEWLMKNMDPLNDNVAALLHQSTDRLTAEIWKD-----------------------------------------VEGIVGLEQVSSLGD------GPPGGRPRRGMFRTVGQLYKESLSRLMATLSNTNPSFVRCIVPNHEKRAGKLEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKGFMD------GKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRH-WQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKEEKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRL---------RRGPLTFTTRTVRQVFR--LEEGVASDEE-AEEAQPGSGPSPEPE------GSPPAHPQ----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B482-1", "uniprot_id": "A0A8M2B482_DANRE", "id": "A0A8M2B482-1", "name": "", "aln": "MSRPAGGSINDVACFLSTGAGPGSPTSVFSAS----------------------------------------SQADWAAKRLVWVPSEKHGFESASIREERGDEVEVELTDSGRKLTLLREELQRMNPPRFSKVEDMADLTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKNLPIYTESIIEMYRGKK------------RHEMPPHIYAISEAAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSHKSGTLGRPKDTVVQMDGTRS--------------------LGRGSSAVNRTVQYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETYLLEKSRAIRQAKDERTFHIFYQLLSGATEAMRKELLLGG--ADQYRFLCGGSL-PVPGQSDSENFTQTMDSMTIMGFTQEESTSMLKVISSVLQFGNITFHKEKNTDQASMPDDTAAQKLCHLLGISVLEFSRAILTPRIKVGREYVQKAQTKQQADFAVEALAKATYERLFRWLVHRINRALDRRQRQGASFIGILDIAGFEIFQLNSFEQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIEWNFIDFGLDLQPCIDLIERPAHPPGVLALLDEECWFPRATDRSFVDKLSAEQGSHSKFMRPRQLKEEADFSIIHYAGKVDYKANEWLVKNMDPLNDNVASLLHQSSDPFISELWREDIQTLPRVYFFDSYATLQTNG-----------------CDSMERIVGLDQVSSGENSGPVSFGAAGLKTKKGMFRTVGQLYKESLTKLMATLRNTNPNFLRCIIPNHEKRAGKLSPHLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYEILTPNAIPRTFMD------GKHASELMISALELDKNLFRVGQSKVFFRAGVLAHLEEERDLKITDTIIRFQSAARGYLARKAFHKKQQQLSALRVMQRNCAAYLKLRN-WQWWRLFTKVKPLLQVTRQDEEIQAREAQLQKAKDKLSKLELDFTELDKKNQQLIEEKSVLTDQLQAEAELFAEAEEMRARLANRKQELEDVLGELESRLEEEEERTVQLTNEKKRIQQHVQDLEEQLEEEEGTRQRLQLEKVTLESKVKSLEAETLTLAEQRDRLSKEKKQLEERLNEVTDQLTEEEEKVKSLNKLKNKQEAVIADIEERLKREEQGRLEQEKWKRRMEGEAVEAQEQLSDMSLLVTELRGSLSQREKEITTLQTRLEEEGARRTEAQRALREAMSQVSELKEEVENERGMRERAEKQRRDLGEELEALRTELEDTLDTTAAQQELRSRREAELGELQRCLEEETRRHEAQLSELRIKHTAAIDSLQEQLDNAKRSRQSLEKAKAVLEEERLNLSAELKTLQGGKMESERGRKRAEGQLQELNARLSQAEREREEREERLGKLQSELESLSSSLSSSDSKSHRLHKEVSSLESQLHDVQELLQEETRQKLALGSRVRALEEEKAGLMERLEEEEEKTRELTRQIQNHTQQLADLKRQTEEVNSAVEAGEETRRKMQRDLENAVQREKSKEEEKERIERQKERLREEIEDMTIALQRERQNCTALEKRQKKFDQCLAEEKAVSARLQEERDRAEAESREKETRFLSLSRALQEATEQRDELERTNKQLRLEMEQLVNAQDDVGKNVHELERSRRALETEAQSLKEQTQELEDELGEAENARLRLEVTLQALRAQFEREISTKEEKGEEKRRALNKQVRELETMLEEEKTQRAQALTVKKQLETELQEAEAQVEAASRGREEAFRQMKRLQTQMKELIRELDETKLARDEIVAQSKDSEKRLQTLEAELLQLTEDLSVSERQKRQAQQERDEMADEIINNATGKSALFDEKRRLETRITQMEEELEEAQSNAELLAERQRKSTLQIETLTVQLSGERTLAQKSESARETLERQNKELKTRLSEMEGAVKGKHRLSVAALEAKIESMEEQVEQERQERAMANKLVRKTEKKLKEVLMQVEDERRHADQYREQLDKSMGRLRQLKRQLEEVEEENSRSNAQRRKLQRELEEMSDSMQSMNRELNTLRSQLSITERQKSEQRAPLPLSMRAGRRALVDDLSQENSDSEDPGASPTPSSGPPGTPTPSDNALGPPPPYSLTDAE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q99323-3", "uniprot_id": "MYSN_DROME", "id": "Q99323-3", "name": "Myosin heavy chain, non-muscle", "aln": "-MKSAWLALKSKSALHPKSEYPVSNIHYPKAANYRQTRNYLEIAAKMSEEVDRNDPELKYLSVERNQFNDPATQAEWTQKRLVWVPHENQGFVAASIKREHGDEVEVELAETGKRVMILRDDIQKMNPPKFDKVEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPYKKLPIYTEKIMERYKGIK------------RHEVPPHVFAITDSAYRNMLGDREDQSILCTGESGAGKTENTKKVIQFLAYVAASKPKGSGAVPHPAVLINFSVNTNKYIKVKIMAQNQNQTIEVVNGLKMVEVNSNCQEGELEQQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDASGFISGANIETYLLEKSRAIRQAKDERTFHIFYQLLAGATPEQREKFILDD--VKSYAFLSNGSL-PVPGVDDYAEFQATVKSMNIMGMTSEDFNSIFRIVSAVLLFGSMKFRQERNNDQATLPDNTVAQKIAHLLGLSVTDMTRAFLTPRIKVGRDFVTKAQTKEQVEFAVEAIAKACYERMFKWLVNRINRSLDRTKRQGASFIGILDMAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWKFIDFGLDLQPTIDLIDKPG---GIMALLDEECWFPKATDKTFVDKLVSAHSMHPKFMKT-DFRGVADFAIVHYAGRVDYSAAKWLMKNMDPLNENIVSLLQGSQDPFVVNIWKD------------------------------------------AEIVGMAQQALTDT-------QFGARTRKGMFRTVSHLYKEQLAKLMDTLRNTNPNFVRCIIPNHEKRAGKIDAPLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYELLTPNVIPKGFMD------GKKACEKMIQALELDSNLYRVGQSKIFFRAGVLAHLEEERDFKISDLIVNFQAFCRGFLARRNYQKRLQQLNAIRIIQRNCAAYLKLRN-WQWWRLYTKVKPLLEVTKQEEKLVQKEDELKQVREKLDTLAKNTQEYERKYQQALVEKTTLAEQLQAEIELCAEAEESRSRLMARKQELEDMMQELETRIEEEEERVLALGGEKKKLELNIQDLEEQLEEEEAARQKLQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKKLLEERANDLSQTLAEEEEKAKHLAKLKAKHEATISELEERLHKDQQQRQESDRSKRKIETEVADLKEQLNERRVQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARAKAEKVRRDLSEELEALKNELLDSLDTTAAQQELRSKREQELATLKKSLEEETVNHEGVLADMRHKHSQELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQENDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKSASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEVTTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKELIAQNDRLDKSKKKIQSELEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSVSRELDEAFDKIEDLENKRKTLQNELDDLANTQGTADKNVHELEKAKRALESQLAELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAKEEGAEEKRRGLVKQLRDLETELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVKEDALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKEAERKVKALEAEVLQLTEDLASSERARRAAETERDELAEEIANNANKGSLMIDEKRRLEARIATLEEELEEEQSNSEVLLDRSRKAQLQIEQLTTELANEKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIATLEAKIANLEEQLENEGKERLLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQMDKLNSRIKLLKRNLDETEEELQKEKTQKRKYQRECEDMIESQEAMNREINSLKTKLR--------RTGGIGLSSSRLTGTPS-------SKRAGGGGGGDDSSVQDESLD------GEDSAN------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08964-1", "uniprot_id": "MYO1_YEAST", "id": "P08964-1", "name": "Myosin-1", "aln": "--MTGGQSCSSNMIVWIPDEKE-------------------------------------------------------VFVKGELMSTDINKNKFTGQEEQIGIVHPLDSTEVSNLVQVRISDVFPVNPSTFDKVENMSELTHLNEPSVLYNLEKRYDCDLIYTYSGLFLVAINPYHNLNLYSEDHINLYHNKHNRLSKSRLDENSHEKLPPHIFAIAEEAYENLLSEGKDQSILVTGESGAGKTENTKKILQYLASITSGSP-----------------------------------------SNIAPVSGSSIVESFEMKILQSNPILESFGNAQTVRNNNSSRFGKFIKIEFNEHGMINGAHIEWYLLEKSRIVHQNSKERNYHIFYQLLSGLDDSELKNLRLKSRNVKDYKILSNSNQDIIPGINDVENFKELLSALNIIGFSKDQIRWIFQVVAIILLIGNIEFVSDR-AEQASFKN--DVSAICSNLGVDEKDFQTAILRPRSKAGKEWVSQSKNSQQAKFILNALSRNLYERLFGYIVDMINKNLDHG-SATLNYIGLLDIAGFEIFENNSFEQLCINYTNEKLQQFFNNHMFVLEQSEYLKENIQWDYIDYGKDLQLTIDLIESKGPPTGVLPLLDEEAVLPKSTDESFYSKLISTWDQNSSKFKRSRLKN--GFILKHYAGDVEYTVEGWLSKNKDPLNDNLLSLLSSSQNDIISKLFQPE--------------------------------------GEKSSSAGVEANISNQE--------VKKSARTSTFKTTSSRHREQQITLLNQLASTHPHFVRCIIPNNVKKVKTFNRRLILDQLRCNGVLEGIRLAREGYPNRIAFQEFFQRYRILYPENSTTTTFSSKLKASTKQNCEFLLTSLQLDTKVYKIGNTKLFFKAGVLADLEKQKDVKLNNIMIKLTATIRGYTVRKEITYHLQKLKKTRVIGNTFRLYNRLVKEDPWFNLFIRIKPLLTSSNDMTRTKKFNEQINKLKNDLQEMESKKKFLEEKNQKTVNELENTQDLLNQEKENLRKNESLLNRVKTSSETLQKQFDDLVSEKDEISREKLEVAQNLEEAHQKIQGLQETIREREATLEKLHSKNNELIKQISDLNCDISKEQSSQSLIKESKLKLENEIKRLKDVINSKEEEIKSFN---DKLSSSEEDLDIKLVTLEKNCNIAMSRLQSLVTENSDLRSKNENFKKEKAALNNQLKNKESELLKMKEKIDNHKKELATFSKQRDDAVSEHGKITAELKETRIQLTEYKSNYQKIKEEYSNFQRETKE-----QEQKKRNSLVESLNDSKIKELEARLSQEISLNQYLNKRISGNSVETNISSTRRSTSYSDDPLDKEDIIKKYYDLQLAFTEITRNLENEIEEKKNLISRLRFTETRLASSSFEDQKIKAQMKKLKKLIQDMDPSIP-----------LDSILNEPLDNCPDKESDINKLMLEVDYLKRQLDIETRAHYDAENAISALHSKFRKIQGESSLSSSDIYKLKFEASEERVKSLEDKLKTMPLRDRTNLPVGDIIKNRDSISKYEEEIRYYKLENYKLQEILNESNGKLSQLTLDLRQSKSKEALLSEQLDRLQKDLESTERQKELLSSTIKQQKQQFENCMDDLQGNELRLREHIHALKQAEEDVKNMASIIEKLKTQNKQKEKLIWER------EMERNDSDMQLQETLLELKRVQDVKKILSDDLAHLKERLSAVEDRSQYTDEINRLKEELNCSLKAETNLKKEFATLKYKLETSTNDSE---AKISDLLKQLDHYTKVVEMLNNEKDAISLAEKELYQKYEALNTECESLKGKIVSLTKIKQELESDLNQKTDALQISNAALSSSTQKNKEITEKIKYLEETLQLQMEQNSRNGELVKTLQASCNGYKDKFDDEKQKNIDLYEENQTLQKLNTDLQLQLKN--LHERLSDTTEKNAWLSKIHELENMVSLETDLKYEEMKKNKSLERAVEELQTKNSQQTDVIELANKNRSEFEEATLKYEAQISDLEKYISQQELEMKKSIRDNSSYRDKVQEMAQEIEFWKSRY---------------------------------ESTMIGSKNIDSNNAQSKIFS------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . . : :. : : :. . : :: :: .. : : .:: :**. *.*.*:*::** ***.***:*:..** ..********* *.:***::* :*:* :: *:. : :.::***::*::: **..:* : :***** **************::*:** :::. .:* ::**:*****:****:**:*:*********:*:*: * * **:** ******* ::* ..* .:*******.* .: * . * :* .. ** : * :.:: ::*: :: ::: :: :* :*.: : :: :**:: : .. :. **:. :: *:* ** *.*:::* :::..:*..* ::*::: ***:* ::* :*: **: .::*:**:******: *****************:**: **:***.** :*.* * ::*:* *** ****: . *::.*****. :*::**.:* .*: . :.. : :: .* : **** *:*.. ** ** ****:*: :** * : : :::: .*: .: . *:*.. ::*. *: * .*:* *:***:**: *:. .:. *:**************:.*:*:**** **** ***.:* *: . :. *: .* :: :*:** :::::*::*:**:*****.**:::*.*:.: :: : : **: .*: : *: . *:: .. * :* : *:.*: ::**** :.: :::: :: . . : : : * : *. * * : *. *: .: *: . :* :. * .. : : :. . ::* *: :. .*.: ::*: :: ::.. : : .... : :.: **:. ... .:**: * : * .: ::: :* :: : : * : :.: : : .* .:*.*: : ::. : : : : .: ::: : . :. :.: ** . :: * : *:: .* * : ** . . :. : . . . . : : : :* : : : . ::. :: : : .. . : : : : :.: : * : * : : .: .: * :. * :: * . : : . : . : : * * : : : . : :.: ...:: : . *.: .: : ::* : . :. * *::* ::.: :: : ::*: . *: .:. * .:: . : . :*: : : : :: :. *. :: : * :.: : :.* :: : :. : : :: ..:*: :: : . * : : *:.. : : . :: : .:: :: : *::* * .: : :: : : :: :: : . : ::::.: :: :** *: .: . : :. . : . :: *: . . . *:: :*: :* : : : :*: . *: :. * : * : :: ::*: : .:: : ..: .: : ::.: *: .: : :: *: .. :. : * :*: :.: . . .. ", "identical_positions": 370, "similar_positions": 653, "identity": "17.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-11", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35524-1", "uniprot_id": "CLCN1_RAT", "id": "P35524-1", "name": "Chloride channel protein 1", "aln": "-------------------------------------------MERSQSQQHGGEQSWWGTAPQYQYMP----FEHCTSYGLPSENGGLQHRPRKDLGPRHNAHPTQIYGHHKEQYSYQAQDRG-------IPKKTDSSSTVDSLDEDHYSKCQDCVHRLGRVLRRKLGEDWIFLVLLGLLMALVSWCMDYVSAKSLQAYKWTYAQMQPSLPLQYLAWVTFPLILILFSALFCQLISPQAVGSGIPEMKTILRGVVLKEYLTLKAFVAKVVALTAGLGSGIPVGKEGPFVHIASICAAVLSKFMSMFSGVYEQPYYYTDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVRNYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLKELPAFAVIGICCGFLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASLTFPPGMGQFMAGELMPREAISTLFDNNTWVKHIGD--PKSLGQSAVWIHPQVNVVIIILLFFVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPEGILFDDIIYKILPGGYAVIGAAALTGAVSHTVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQLSKFTIFVEDIMVRDVKFVSASCTYGELRNLLQT-TTVKTLPLVDSKDSMILLGSVERSELQSLLQRHLCAERRLKAAQDMARKLSELPYN---------------------------GQAQLAGEWHPG----------------------------------GRPESFAFVDEDED----------EDVSRKTELPQTPTPPPPPPPPLPPQFPIAPSYPEEPNGP----------------------------------LPSHKQPPEASDSADQRSSIFQRLLHCLLGKAHSTKK-----------------------------------------------------------KITQDSTDLVDNMSPEEIEAWEREQLSQPVCFD--FCCIDQSPFQLVEQTTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEELQKAIKGHTKSGVQLRPPLASFRNTTSIRKTPGGPPPPAESWNVPEGEDGAPEREVMVPTMPETPVPPPSPEVPSCLAPARVEGELEELEMVGNLGPEEDLADILHGPSLRSTDEEDEDELIL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64347-1", "uniprot_id": "CLCN1_MOUSE", "id": "Q64347-1", "name": "Chloride channel protein 1", "aln": "-------------------------------------------MERSQSQRHGGEQSWWGSAPQYQYMP----FEHCTSYGLPSENGGLQHRPRKDMGPRHNAHPTQIYGHQKEQYSYKAQDGG-------MPKKMGSSSTMDSLDEDHYSKCQDCVHRLGRVLRRKLGEDWIFLVLLGLLMALVSWCMDYVSAKSLQAYKWTYAQMKPSLPLQYLAWVTFPLILILFSALFCQLISPQAVGSGIPEMKTILRGVVLKEYLTLKAFVAKVVALTAGLGSGIPVGKEGPFVHIASICAAVLSKFMSMFSGVYEQPYYYTDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVRNYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLKELPAFAVIGICCGFLGAVFVYLHRQVMLGVRKHKCLSQFLAKHRLLYPGIVTFVIASLTFPPGMGQFMAGELMPREAISTLFDNNTWVKHIGD--PQSLGQSAVWLHPQVNVIIIILLFFVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPEGILFDDIIYKILPGGYAVIGAAALTGAVSHTVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQLSKFTIFVEDIMVRDVKFVSASCTYGELRNLLQA-TTVKTLPLVDSKDSMILLGSVERSELQSLLQRHLCAERRLKAAQDMARKLSELPYN---------------------------GKAQLAGDWHPG----------------------------------GRPESFAFVDEDED----------EDLSRKMELPLTPAPPPPSPPPPPSQFPIAPSNPEEPNGP----------------------------------LPSHKQPPEASDSADQRSSTFQRLLHCLLGKAHSKKK-----------------------------------------------------------KITQDSTDLVDNMSPEEIEAWEREQLSQPVCFD--CCCIDQSPFQLVEQTTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEELQKAIEGHTKSGVQLRPPLASFRNTTSIRKTPGGPPPPAEGWNVPEDGDGAPGREVMVPTMPETPVPPPSPEAPSCLAPARAEGELEELEMVGSLEPEEELADILHGPSLRSTDEEDEDELIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35523-1", "uniprot_id": "CLCN1_HUMAN", "id": "P35523-1", "name": "Chloride channel protein 1", "aln": "-------------------------------------------MEQSRSQQRGGEQSWWGSDPQYQYMP----FEHCTSYGLPSENGGLQHRLRKDAGPRHNVHPTQIYGHHKEQFSDREQDIG-------MPKKTGSSSTVDSKDEDHYSKCQDCIHRLGQVVRRKLGEDGIFLVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQFLVWVTFPLVLILFSALFCHLISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHIASICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVRNYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLKELPAFAAIGICCGLLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASFTFPPGMGQFMAGELMPREAISTLFDNNTWVKHAGD--PESLGQSAVWIHPRVNVVIIIFLFFVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAALTGAVSHTVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQLSKYTIFVEDIMVRDVKFVSASYTYGELRTLLQT-TTVKTLPLVDSKDSMILLGSVERSELQALLQRHLCPERRLRAAQEMARKLSELPYD---------------------------GKARLAGEGLPGA-------------------------------PPGRPESFAFVDEDED----------EDLSGKSELPPSLALHPSTTAPLS---------PEEPNGP----------------------------------LPGHKQQPEAPEPAGQRPSIFQSLLHCLLGRARPTKK-----------------------------------------------------------KTTQDSTDLVDNMSPEEIEAWEQEQLSQPVCFD--SCCIDQSPFQLVEQTTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEELQKAIEGHTKSGVQLRPPLASFRNTTSTRKSTGAPPSSAENWNLPEDRPGATGTGDVIAASPETPVPSPSPEPPLSLAPGKVEGELEELELVESPGLEEELADILQGPSLRSTDEEDEDELIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HJB7-1", "uniprot_id": "A0AC58HJB7_DANRE", "id": "A0AC58HJB7-1", "name": "", "aln": "-------------------------------------------MIR---EPINTFETVLNFDQVLLYG------EYREQLGNISRREATRLLTEKQWKRHADNSKATRRGHGRAHHASLDVGPL-------TPGLSPSSSLIKS---HPYFKCQDCLARVQRYIVTKLGEDWIFLVLLGLTMALVSWSMDYASAKSIQAYKWMYGELKGNVALQYLAWVSYPIILVVFASLFCHLVAPQAIGSGIPELKTILRGVVLKEYLTLKAFVAKVIGLTAGLGSGMPIGKEGPFVHIASICAAVLSRVMSIFTGVYENSAHVQDLLVCACAVGVATCFAAPVGGVLFSIEVTSTYFAVRNYWRGYFAATFSAFIFRVLSVWNKDSVTITALFRTNFRMDFPFDLQELPAFAIIGISCGFLGAFFVYLNRQVVLIMRRPTALTRFLTKHRLIYPGAVTLIIASFTFPPGFGQFMAGELMPRECINSLFDNYTWTKIWGSPVPPGLGRSAAWLHPQVSVFVILLLFFVMKFWMSAVSTTMPVPSGAFMPVFILGAAFGRLVGEIMATLFPNGILFDGIVYQILPGGYAVIGAAAMTGAVTHTVSTAVICFELTGQISHILPMMVAVILANMVAQGLQPSLYDSIIQVKKLPYLPELGIGHISKYNIFVEDIMVKKIKFLSPQSTYRELKDLLES-TSLKTIPLIDSKDTMILLGSIERCELQAALDWWLSAERRVYNRGE--------------------------------------GMASLVSE--------------------------------------GSWESFVFVDEEVG----------EENRDKGNRVSEECNGPVGSSKTT-----DISTNHTTSGA----------------------------------LKSMRRTFQRLFSSSS-SSGQTKPEFTKLSPAGGVK--------------------------------------------------------------SPAAPPVVDNMTPEEIKAWEEKELDKPIGID--QIRVDPSPFQLVERTSLHKTHTLFSLLGLSHAYVTSIGKLVGVVALKELQKAIEGSTRSGVRLRPPLASFRDARRKTKKPSHSPSIPS---SPTQDIELWSEAVRRESKEESAGSCIQTVEKECESSRNIVSTSEEQLPSSSTVPLSSLHSVPGGEGD-AEKERDEEPL--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VGH7-1", "uniprot_id": "CLCN2_DROME", "id": "Q9VGH7-1", "name": "Chloride channel protein 2", "aln": "MVYFGDRQRDRNRDRSNQKVERIIHDEEFGEENVELVDSEWADFEKFICQLRKRRNSAMSMEEELRHVQRHPKIKSHAFYPCPPPAENARDSDSSDDDDPIGYIDTLMYGRYTKDLGEFAKDEARKLKILEKRRKQEDKQRNKELLGKHSTRAKRVSSWIWRHTVARLGEDWVFLALLGIIMALLSFIMDKGISICTNARIWLYRDLTSQPFVQYIAWVSLPVCLILFSAGFVHLIAPQSIGSGIPEMKTILRGVQLKEYLTFKTLVAKVIGLTATLGSGMPLGKEGPFVHIASIVAQLLSKLVTSFQGIYENESRNSEMLAAACAVGVGACFAAPVGGVLFSIEVTTTYFAVRNYWRGFFAAVCGATVFRLLAVWFQNADTVRALFLTNFTTEFPFDPQELFVFALIGLVCGLGGASYVWVHRRYVLFMRSNKRMNKFLQKNRFLYPGFLALLVSSISFPLGTGQFLAGELSTHEQVTQLFSNFTWSRDDLT--VEQAAVVTHWMTSYTSVFGNLVIYTLFTFVVSIIASTIPVPSGMFIPVFKIGAGFGRLVGEFMAVTFPHGVRYGGRLSPIMPGGYAVVGAAAFSGSVTHTVSVAVIIFEMTGQITHVVPVMIAVLVANAVAALLQPSIYDSIILIKKLPYLPDLLPSSSGMYSIFVEDFMVRDVKYIWHGISYQKLKEVLKLNKTLRSLPLVDSPDNMILLGSVQRYELIKMIEKHIGREKRMEVAQKWQKEAQERALEEEKKKQEVELKMRRPSRFEVLPAPDILSLRQIANDEMLPPKKRAETMHGSLAPRKSILKKTNSFNLKTYAQPMGHSPSITPYTTITGNSEFRIRSAFEAIFKKSTTLQDVQPDPETGSLSPAASNHEVEVPRTPSTPGVSKKVQLPAQSNWDFVTDQIMLQVNPISTESNKMPAEKDFTDKALSNNGDSSKQSPSIKFKANKVADVNRSPQTAKRCSKIRFANEVGVNGSPTRTKCKIKPENVLGYSIEDVDETTNPESLAESIQKPKSVRLPRERVIDMSPEDQKQWELEEMLKPIDLQKANVHIDPSPFQLVERTSILKVHSLFSMVGINHAYVTKIGRLVGVVGLKELRKAIEDINSN-----SFVPPTRDEDADEKPAVEKPLLSTN---------------SSDKAVDMTVTSMDSALSNSENCSDIEMEHIKHTDKGTVSLTMPPQESKQSPSADKSNTENGNHA--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :: . : : . : .: . : *: . . . ... .. . :.: : : :**** :**.***: ***:*: ** : . :* * * :: . :*::.**: *: *::*:: * :*::**::******:******* ******:*::****:.*** ****:*:************ * :**:.:: * *:**: ::*. .*****. **.:*:**********:***********:***. .* :**:*:** ::: *: *** *** :**** :** .** **: **: ** :*:::*: :* :* . :.:** *:*::*** ::::::*::** * ***:**** .:* :. **.* ** : . : *: . ..*. :.:: ::.* :* :::*:*:*.* *:*** :**.*******:** **.*: :.. : *:******:****::*:*:****.*** **:****:*::*:*:**::** ** ****:***** :*******:* . . :.*****:**:.:*:: :* :*: :*: .:::::**:** *.******::* ** :: : *:*: . . :..: * *:. . * * * . . . .. . : . : : . . .* . . : . * :*:**: : ** ::: :*: :: :* *******:*:: *.*:***::*: ****.:*:* **:.*:**:***:. . . . :.. *: * . * . : . . .. . : . . . . . .: : ", "identical_positions": 318, "similar_positions": 282, "identity": "26.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-13", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PQJ7-1", "uniprot_id": "TBCEL_RAT", "id": "Q5PQJ7-1", "name": "Tubulin-specific chaperone cofactor E-like protein", "aln": "----------------MDQPSGRSFMQVLCEKYSPENFPYRRG----------------PGMGVHVPATPQGSPMKDRLNLPSVLVLNSCGITCAGDEREIAAFCAHVSELDLSDNK--------------------LQDWHEVSKIVSNVPQLEFLNLSSNPLSLSVLERTCAGSFSGVRKLVLNNSKAS--WETVHTILQELPDLEELFLCLNDYETVSCPSVCCHSLKLLHITDNNLQEWTEIRKLGVMFPSLDTLVLANN------------HVNAIEEPADSLAR----LFPNLRSISLHKSGLQSWEDIDKLN-SFPKLEEVRLLG--IPLLQPYTTEERRK---LVVARLPSVSKLNGSVVTDGEREDSERFFIRYYVD--VPQEEVPFRYHELITKYG----KLEPLAEVDLRPQSSAKVEVHFN---DQVEEVSIRLDQTVAELKRQLKTLVQLPTSSMLLYYFDHEAPFG--PEEMKYSSRALHSFGIRDGDKIFVESKTK-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C5W3-1", "uniprot_id": "TBCEL_MOUSE", "id": "Q8C5W3-1", "name": "Tubulin-specific chaperone cofactor E-like protein", "aln": "----------------MDQPSGRSFMQVLCEKYSPENFPYRRG----------------PGVGVHVPATPQGSPMKDRLNLPSVLVLNSCGITCAGDEREIAAFCAHVSELDLSDNK--------------------LQDWHEVSKIVSNVPQLEFLNLSSNPLSLSVLERTCAGSFSGVRKLVLNNSKAS--WETVHTILQELPELEELFLCLNDYETVSCPSVCCHSLKLLHITDNNLQDWTEIRKLGVMFPSLDTLVLANN------------HLNAIEEPADSLAR----LFPNLRSISLHKSGLQSWEDIDKLN-SFPKLEEVRLLG--IPLLQPYTTEERRK---LVVARLPSVSKLNGSVVTDGEREDSERFFIRYYVD--VPQEEVPFRYHELITKYG----KLEPLAEVDLRPQSSAKVEVHFN---DQVEEMSIRLDQTVAELKKQLKTLVQLPTSSMLLYYFDHEAPFG--PEEMKYSSRALHSFGIRDGDKIFVESKTK-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5QJ74-1", "uniprot_id": "TBCEL_HUMAN", "id": "Q5QJ74-1", "name": "Tubulin-specific chaperone cofactor E-like protein", "aln": "----------------MDQPSGRSFMQVLCEKYSPENFPYRRG----------------PGMGVHVPATPQGSPMKDRLNLPSVLVLNSCGITCAGDEKEIAAFCAHVSELDLSDNK--------------------LEDWHEVSKIVSNVPQLEFLNLSSNPLNLSVLERTCAGSFSGVRKLVLNNSKAS--WETVHMILQELPDLEELFLCLNDYETVSCPSICCHSLKLLHITDNNLQDWTEIRKLGVMFPSLDTLVLANN------------HLNAIEEPDDSLAR----LFPNLRSISLHKSGLQSWEDIDKLN-SFPKLEEVRLLG--IPLLQPYTTEERRK---LVIARLPSVSKLNGSVVTDGEREDSERFFIRYYVD--VPQEEVPFRYHELITKYG----KLEPLAEVDLRPQSSAKVEVHFN---DQVEEMSIRLDQTVAELKKQLKTLVQLPTSNMLLYYFDHEAPFG--PEEMKYSSRALHSFGIRDGDKIYVESKTK-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QCV6-1", "uniprot_id": "E9QCV6_DANRE", "id": "E9QCV6-1", "name": "", "aln": "--------------MESEETEGRTLVQVISEKYSPDNFPYCRG----------------PGVGVVIRSSPQGSPVKDRLNLPSILVLDGCGITEAGDEEEVATFCAHVVELDLSHNQ--------------------LKDWGEISKILSNIPNLDFLNLSMNPLHGSSLEPCLAEAFSGLRRLVLNNTHVT--WDMVHTLTREIPDLEELFLCLNEYESVNASSMPCPSLRLLHITDNQLQDWVEVRKLGLMYPGLVSLILSNN------------SLSSIHEPEDSLHR----LFPNLRSINLHNSGLSRWEDVEKLN-FFPKLQEVRVMG--IPLLQPYTDQERRC---LMVAQLPHVTVLNGSVVTDGEREDAERFFIRYHLD--CPEDELPQRYHTLVARYG----RLAPLAEVDLRPLSHVQVQVRFG---DQAKSLELRLDQTVADLKKQLKTVVQLPPNKIRVYYIDRQLGYALEPQEMKYGARALHSYSIRDGDEIMVVPKTQ-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P39937-1", "uniprot_id": "PAC2_YEAST", "id": "P39937-1", "name": "Protein PAC2", "aln": "MTYEIGDRLKIGGYFCTIKFIGVIKPWPSVKAYGVEWDDHSRGKHSGTIDDIHYFDVQIPNSGSFLKESKIKSPGVRRITFYEALSEKYGGSSNNINDLSIGNKRVEGLGFDELNARNKNYKKLRKIALRDSDVAILFQNQDELNRVIQNCVNVKDLDLSLNLFTNINSLCEFIEPLKNLESLNISQNKLLSGWDNLKEYDLSHIKTLRLSSCGLSYKHIGKLLKSFRTLKMLDLSYNNLTSAGIQNFENEIPCTLEELNISGNNLISFPLFPKNLTLKGLNVSNNQISRAPSIAIYSVESLDITDNKFKERSLIDDLNKTFPSLKNIHLSGNEFNYNGNYINVEEQATFYEVLARFDRVMVLNGSICDVKTRREAEMFFVSKVMNNELSYDTNLPRWSSLIKSYEIDMSKLSFNNERETRQSLVLKIKIRAGKKPSSDLDYWVLPSFTVRYVKSVICRKLNFDILNVKLFHENSEGMIN----EIKYNFRPISDFNVVNGDIIHVSSPVNNKSIQKVNSPS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : *. : : ** *. * : : ** *:.: . * . * : :: .:. .. :* . : ::: *:.:::.* ::. *:** * : .:..:. * :.:.: *: :: . . .* * .*: :. :*::*.:: *:* . . . : * * ::.* :..:. . :.: * : .:.*:.: .. :. . ::.** **.*::::: * : * *.: ::*:: * ****: *.::* **: :: . : *: *: * :* * : * ::::: . .. . : . ** :* : ::: .: ::: : : *:**. *.: .:.: :** * * . .: ", "identical_positions": 67, "similar_positions": 158, "identity": "12.84%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96PV0-1", "uniprot_id": "SYGP1_HUMAN", "id": "Q96PV0-1", "name": "Ras/Rap GTPase-activating protein SynGAP", "aln": "MSRSRASIHRGSIPAMSYAPFRDVR--GPSMHRTQ--YVHSP-YDRPGWNPRFCIISGNQLLMLDEDEIHPLLIRDRRSESSRNKLLRRTVSVPVEGRPHGEHEYHLGRSRRKSVPGGKQYSMEGAPAAP------------FRPS------------------------------------------------------------------------------------QGFLSRRLKSSIKRTKSQPKLDRTSSFR-QILPRFRSADHDRARLMQSFKESHSHESLLSPSSAAEALELNLDEDSIIKPVHSSILGQEFCFEVTTSSGTKCFACRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPPKKRYYCELCLDDMLYARTTSKPRSASGDTVFWGEHFEFNNLPAVRALRLHLYRDSDKKRKKDKAGYVGLVTVPVATLAGRHFTEQWYPVTLPTGSGGSGGMGSGGGGGSGGGSGGKGKGGCPAVRLKARYQTMSILPMELYKEFAEYVTNHYRMLCAVLEPALNVKGKEEVASALVHILQSTGKAKDFLSDMAMSEVDRFMEREHLIFRENTLATKAIEEYMRLIGQKYLKDAIGEFIRALYESEENCEVDPIKCTASSLAEHQANLRMCCELALCKVVNSHCVFPRELKEVFASWRLRCAERGREDIADRLISASLFLRFLCPAIMSPSLFGLMQEYPDEQTSRTLTLIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGSMQQFLYEISNLDTLTNSSSFEGYIDLGRELSTLHALLWEVLPQLS-----------KEALLKLGPLPRLLNDISTALRNPNIQRQPSRQSERPRPQ---------PVVLRGPSAEMQGYMMRDLNSSIDLQSFMARGLNSSMDMARLPSPTK-----EKPPPPPPGGGKDLFYVSRPPLARSSPAYCTSSSDITEPEQKMLSVNKSVSMLDLQGDGPGGRLNSSSVSNLAAVGDLLHSSQASLTAALGLRPAPAGRLSQGSGSSITAAGMRLS---QMGVTTDGVPAQQ------LRIPLSFQNPLFHMAADGPGPPGGHGGGGGHGPPSSHHHHHHHHHHRGGEPPGDTFAPFHGYSKSEDLSSGVPKP--PAASILHSHSYSDEFGPSG-TDFTRRQLSLQDNLQHMLSPPQITIGPQRPAPSGPGGGSGGGSGGGGGGQPPPLQRGKSQQLTVSAAQ-----KPRPSSGNLLQSPEPSYG-----------------PARPRQQSLSKE--GSIGGSGGSGGGGGGG--------------LKPSITKQHS-QTPSTLNPTMPASERTVAWVSNMPHLSADIESAHIEREEYKLKEYSKSMDESRLDRVKEYEEEIHSLKERLHMSNRKLEEYERRLLSQEEQTSKILMQYQARLEQSEKRLRQQQAEKDSQIKSIIGRLMLVEEELRRDHPAMAEPLPEPKKRLLDAQERQLPPLGPTNPRVTLA---------------------PPWNGLAPPAPPPPPR----LQITENGEFRNTADH----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F1U4-1", "uniprot_id": "E7F1U4_DANRE", "id": "E7F1U4-1", "name": "", "aln": "---------------MSYVPFQDARYAVPPSYRPQPSFAAAPSYEQADWNPRLGVISGNQLYMLDQEEVHPLLMRERRSESHRNKLLRRTVSVPVEARHH--PEMDAARLRRKSIATGKQPSMEIPPTAPPQPFRQSVSNPPFRPRSLSPSLSLSLPFAPSPLSPSLSPSHLQSQKRISTPPLPRSLPLSPSVSLTLPPSVPLSHWAAGEWKVVGSNPGTGSSVAALPSLESFLSRRLKGSIKRAKSQPKLDRTSSFRHMILPRFRSADQERTRLMQSFKESHSHESLLSPSSAAEALDLTLDEDAIIKPVHSSILGQEYCFEVITASGTKCFACRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPPKKRYYCELCLDDMLYARTTSKPR---TDTVFWGEHFEFNNLPAVRNLRLHLYKETDKKRRKEKSTYLGLVSIPISSITGRQFVEQWYPVIQPSVLAKGGGVG-----------GGKIIN--ASLRLKSRFQTMSILPMELYKEFAEYVTNNYRTLCAVLEPLLSVKSKEEVACALVHILQSTGKAKDFLSDMAMCEVDRFIDREHLIFRENTLATKAIEEYLKLIGHKYLKDVLGDFIRALYESEENCEVDPMRTPPSILPEHQANLRMCCELALCKIINSYCAFPRELKEVFASWRVRCAERGREDIADRLISGSLFLRFLCPAIMSPSLFNLTQEYPDEQTSRTLTLIAKVVQNLANFSKFGSKEEYMCFMNEFLEMEWGSMQQFLYEISNLDSVSNAGAFEGYIDLGRELSILHSLLWEVMAQLSKSSIRSWFIVSKDAIIKLGPLPRLLNDISMALRNPHLQRQPSHQTDRQPAERQTDRLLSRPSFNRGVSSEFQNLMMRDLNSSVEITRLPSP--TSAMSSGGAPPSRAGMAGFADRDHPHRASSKDVFYGARPPLARSSPAYCTSSSDITDPDPKDSRMN-SVSNLQSMGD----MLNSSQAS-IAGLG--SYGGLAGLGGGLGGQLRAGGRMSAGSGGSSMSGGLRLSQLSQMGTTTDSLSQQQQQQAAALRFPLSFQNPLFHLAADGPQLHHQHSR--AQPPPP----LLLAPEPDGSHPTYIPQFAHGGFSRSEDLSTLRPGPHLGQPSIIHSHSYSDDYSRHNQSDYGRRQISMHMQEQQQMAGMASQTGTSHSSLATPPSTVQPVRQSSMAPPTQRMKSQPSHQLSVSSAAGAPASKTRPQSGNLLQSPESGFGGRQQGPRQQLSVKDSTPPGLPHQQSSTRESQGSQGSQGGTPQSTQQSKSHQERQQVQQQHLLKPTMSKQGSSQSPSTLNPQTPASERTVAWVSNMPHLSADIESSRIDREEFKLKEYSKSMDESRLDRVREYEEEIHSLKERLMMSHRKLEEYERRLLTQEQQTNKILLQYQSRLDDSERRLRQQQMEKDNQIKGIIDRLMAVEDELR------VGVVPEHKPRVFADQEKQLSALGSADPGVSFGGEMTSASGFVGVSPSDKSSTRSPQNGIASFPLVPPPRSIPHAQLWPNGNQKSAMDWRASLEGEQVNNNANQI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***.**:*.* *. :*.* :. :* *::..****: :****** ***::*:****:*:***** **************.* * * . .* ****:. *** *** .*:** *** :.*******.****:************* *********::*:*************************:*.****:*************:**** *:************************************************************************** ****************** ******:::****:*:*: *:***::*:::::**:*.****** *: . .**:* *** . .::***:*:********************:** ******* *.**.*****.*********************.*****::*******************::***:*****.:*:****************:: ..* *.****************::**:*.*************:****************.*****************.* ******************:********* ***::: *******:****************:::*:.:************ **:*****:.*** *:*::************* *****::*****:*::* .: * . ** *:*:*. ********::: : : .*:*. . *.. . * ...**:** :*******************:*: * :* *** *: ** ****..* :*.:* :.. *.* ..** : ..**:* ***.* :.*:*** ***.***.:. ** **:**********:***** *. .: **. . *..*. . .. *:*:*****: * * .**:*******::. . :*: ***:*:: : *: :: *..:.: : * . .. . . :: *:**:**:* *.**.*********..:* *. *:*** ::* ** *..**: . . ***:::** * *:****** **********************::*:***:*****************:************* **:***********:**:**.***:***:**::**:****** ***.***.**.*** **:*** . :** * *:: **:**..**.::* *::. .* **:*. . **** *: **: :.: * ", "identical_positions": 859, "similar_positions": 267, "identity": "54.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-24", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PB44-1", "uniprot_id": "PTN23_MOUSE", "id": "Q6PB44-1", "name": "Tyrosine-protein phosphatase non-receptor type 23", "aln": "MEAVPRMPMIWLDLKEAGDFHFQSAVKKFVLKNYGENPEAYNEELKKLELLRQNAIRVARDFEGCSVLRKYLGQLHYLQSRVPMGSGQEAAVAVTWTEIFSGKSVSHEDIKYEQACILYNLGALHSMLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAFSVDMSRQILTLNVNLMLGQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEACRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVAYFQSALDKLNEAIKLAKGQPDTVQDALRFAMDVIGGKYNSAKKDNDFIYHEAVPALDTLQPVKGAPLVKPLPVNPTDPAVTGPDIFAKLVPMAAHEASSLYSEEKAKLLREMLAKIEDKNEVLDQFMDSMQLDPETVDNLDAYNHIPPQLMEKCAALSVRPDTVKNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELQEQKLQETLGQAGAGPGPSVAKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVGNLRLLSGPLDQVRAALPTPALTPEDKAVLQNLKRILAKVQEMRDQRVSLEQQLRELIQKDDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQDNVLRALTEANVQYAAVRRVLSELDQKWNSTLQTLVASYEAYEDLMKKSQEGKDFYADLESKVATLLERAQSICRAQEAARQQLLDRELKKKAPPPRPTAPKPLLSR--------REEGEAVEA--------GDTPEELRSLPPDMMVG----------PRLPDPFLGTTAPLHFSPGPFPSSTGPA----------THYLSGPLPPGTYS-GPTQLMQPRA----AVPMAPATVLYPAPAYT---SELGLVPRSSPQHGIVSSPYAGVGPPQPVVGLPS--------------APPPQLSGPELAMTVRPATTTVDSVQAPISSHTAPRP----------NPTPALPQPCFPVPQPVPQSVPQPQPLPVP------YTYSIG--------------------------------TKQPLPAPYTYSIGTKQHL----TGPLPQHQFPPG------------IPTGFPVPRTGPQAQAQPQPQPQPQPQPQPQP----------------QPQPQPQSQSQPQPQPQPQPQRPAFGPQ--------PTQQPLPFQ----------------------------HPHLFPSQAPGILPPPPPTPYHFTP-----------------QPGVLGQPPPTLHTQLYPGPSQDPLP-----------PHSGALPFPS--PGPPHP-HPTLAYG-PAPSPRPLGPQATP-------------------------------VSIRGPPPASQPTPSPHLVPSPAPSPGPGPVPS-------RPPTAEPPP--------------------------CLRRGAAAADLLSSSPESQHGGTQPPGGGQPLLQPTKVDAAE---GRRPQALRLIEQDPYEHPERLQQLQQELEAFRG---------QLGDAGALDAIWRELQEAQEHDARGRSIAIARCYSLKNRHQDVMPYDSNRVVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTERGQPMVHGALSVALSSIRTTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPGNLLRFIQEVHAHYLHQRPLHTPIVVHCSSGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRKHMLQEKLHLKFCHEALVRHVEQVLQRHGVPPPGKPVASVNISQKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPL------------GGLDSPAASL--PGLVEPPGLPPASLPESTPVPSSSPPPLSSP----------------------LPEAPQPEEEPSVPEAP--SLGPPSSSLELLASLTPEAFSLDSSLRGKQRMSKQNFLQAHNGQGLRAAQPTDDPLSLLDPLWTLNKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H3S7-1", "uniprot_id": "PTN23_HUMAN", "id": "Q9H3S7-1", "name": "Tyrosine-protein phosphatase non-receptor type 23", "aln": "MEAVPRMPMIWLDLKEAGDFHFQPAVKKFVLKNYGENPEAYNEELKKLELLRQNAVRVPRDFEGCSVLRKYLGQLHYLQSRVPMGSGQEAAVPVTWTEIFSGKSVAHEDIKYEQACILYNLGALHSMLGAMDKRVSEEGMKVSCTHFQCAAGAFAYLREHFPQAYSVDMSRQILTLNVNLMLGQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEACRALENPDTASLLGRIQKDWKKLVQMKIYYFAAVAHLHMGKQAEEQQKFGERVAYFQSALDKLNEAIKLAKGQPDTVQDALRFTMDVIGGKYNSAKKDNDFIYHEAVPALDTLQPVKGAPLVKPLPVNPTDPAVTGPDIFAKLVPMAAHEASSLYSEEKAKLLREMMAKIEDKNEVLDQFMDSMQLDPETVDNLDAYSHIPPQLMEKCAALSVRPDTVRNLVQSMQVLSGVFTDVEASLKDIRDLLEEDELLEQKFQEAVGQAGAIS--ITSKAELAEVRREWAKYMEVHEKASFTNSELHRAMNLHVGNLRLLSGPLDQVRAALPTPALSPEDKAVLQNLKRILAKVQEMRDQRVSLEQQLRELIQKDDITASLVTTDHSEMKKLFEEQLKKYDQLKVYLEQNLAAQDRVLCALTEANVQYAAVRRVLSDLDQKWNSTLQTLVASYEAYEDLMKKSQEGRDFYADLESKVAALLERTQSTCQAREAARQQLLDRELKKK-PPPRPTAPKPLLPR--------REESEAVEA--------GDPPEELRSLPPDMVAG----------PRLPDTFLGSATPLHFPPSPFPSSTGPG----------PHYLSGPLPPGTYS-GPTQLIQPRAPGPHAMPVAPGPALYPAPAYT---PELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPS--------------APPPQFSGPELAMAVRPATTTVDSIQAPIPSHTAPRP----------NPTPAPPPPCFPVPP--------PQPLPTP------YTYPAG--------------------------------AKQPIPA---------------------QHHFSSG------------IPAGFPAPRIG----------------PQPQP----------------HPQPHPS---------------QAFGPQ--------PPQQPLPLQ----------------------------HPHLFPPQAPGLLPPQ--SPYPYAP-----------------QPGVLGQPPPPLHTQLYPGPAQDPLP-----------AHSGALPFPS--PGPPQPPHPPLAYG-PAPSTRPMGPQAAP-------------------------------LTIRGPSSAGQSTPSPHLVPSPAPSPGPGPVPP-------RPPAAEPPP--------------------------CLRRGAAAADLLSSSPESQHGGTQSPGGGQPLLQPTKVDAAE---GRRPQALRLIERDPYEHPERLRQLQQELEAFRG---------QLGDVGALDTVWRELQDAQEHDARGRSIAIARCYSLKNRHQDVMPYDSNRVVLRSGKDDYINASCVEGLSPYCPPLVATQAPLPGTAADFWLMVHEQKVSVIVMLVSEAEMEKQKVARYFPTERGQPMVHGALSLALSSVRSTETHVERVLSLQFRDQSLKRSLVHLHFPTWPELGLPDSPSNLLRFIQEVHAHYLHQRPLHTPIIVHCSSGVGRTGAFALLYAAVQEVEAGNGIPELPQLVRRMRQQRKHMLQEKLHLRFCYEAVVRHVEQVLQRHGVPPPCKPLASASISQKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPP------------GGLESPVASL--PGPAEPPGLPPASLPESTPIPSSSPPPLSSP----------------------LPEAPQPKEEPPVPEAP--SSGPPSSSLELLASLTPEAFSLDSSLRGKQRMSKHNFLQAHNGQGLRATRPSDDPLSLLDPLWTLNKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q653-1", "uniprot_id": "F1Q653_DANRE", "id": "F1Q653-1", "name": "Tyrosine-protein phosphatase non-receptor type 23", "aln": "MEAVPRMPMIWLDLKEAGEFQFSPTVKQFILKNYGEDPDNYNEQLKKLEQLRQSAVNVTRDFEGCSTLRKYFGQLHYLQSRVPLGLGQEAAVPISWTEIFSGKTVTHEDICYEQACILYNLGALHSMLGAMDNRVSEEGMKVSCTHFQCSAGAFAYLRDHFSHSYSVDMSHQILNLNINLMLGQAQECLLEKSMLDNRKSFLVARISAQVVDYYKEACRALENSETASMLGKIQKDWKKLVQMKIYYFAAIAHLHMGKQAEEQQKYGERVAYLQSSLDKLGEAIKLAKGQPDSVQEALRFTMDVIGGKFNSAKKDNDFIYHESVPSLETLTSVKGAPLVKALPVNPTDPSVTGPDIFAKLVPMAAHEASSLYSEEKAKLLRDVMAKVDNKNETLEQFMDSLGLDPESVDNMEMYNTLPTVLMEKCAALSVRPDTVKNLIQSMQVLSGVFTDVEASLREIRDVLDEDETEEQSLEEAVGKQAVPE----RPSTLAELRRDLEKYLEAHEKASFTNTELHRAMNLHISNLRLLGGPLDTLREALPRPQLSEDEMAGLQTMKRILGKVQEMRDQRSSLEKQLRDLIQQDDITTALVTTERADMKKLFEEQLKKYEQVKVYIDQNLAAQENILKALTEANVQYATVRKGLTETEHKWNSTVQMLVASYEAYEDLMKKSQEGKEFYEDLETKASRLLEKSKTVCKARKEERQAITERELKKK-APQRPTAPKPAQNKGQNMGPSISDDPELAELSAAILALGGDLPEELRSLPPELTIPSSAHPVSGAAPGSVLRWPGANSTLHYGQHRFPQNLPPPEVLAQISRFPTPPLSQSFSPSVPQPSLMQQQFPQMPNPQVLPPPPVSGYHPQPSQNQPGPSVTAVRPSTTTVDSIQTPITSYSPASAQAVMPSPGQHQVPHPISSVYATPPQMA-PHVQYMQQPGVPMSQPPQAMPAPHPQPQPQVFAQQGGQNQPQPFYPQAVLPSQQQMPRPLTGSQPSQHTTPQFPQYIRQPGPPNFQQPQMQGQFRAPPSHAPPHQGYPPVSFVPKAPLPQVNTINPGQMSHSGVSPQMPLSSHPVPPVSMPHLAHVNQHIPPSSQPVPSMSMPHLARVNLQIAPSSQPVSSASMPHLAHVSQQIPPASQPQPPPVNHLSHPPHRQIHPSSHHLGPTPHMQIPAAPTQMPPPQQPQMHASSTHMSPPHPQMPSVSQPPPHCPQSHIIPAHQPNQQPPYPAVPMQATVPIQPQAPHGSLPSQVQIHPNTPSQHQNHPHPQIIPQSCPPALPHNMYKPQPTITPISAPMSFPGGVPMVPHQSVPSLQPQSQPPSSKPLVPQQLPPGGPISYAVPQVGNIPPGAMQHPVATASPGPQSMIPPSSGAPGAPQPHVLPSPAPSPSPSPGPPSLGMTTQRPSPALTPVGGAAMPQSSVQGPAPTGTMPQPDSTLFQRQNSSTDDLLSSSPESQHGGTKDT---ACVLLPTKADPQEEHHRKKAEGVRLIQGDPYQAPERVSKLSAQLERFRSTVQSLERPTGEGGLSELDAQWKELQEQQEKDTRQLSIAIARCYTMKNRHQDVMPYDCNRVVLHSGKDDYINASFTEDLSPYCPRLIATQAPLTGTAADFWLMVYEQKVSVIVMLVSEQELEKQKVLRYFPSERGQQLAQGPITLTLTTQKSTPTHIERMIGLQYRDQSLRRTVVHLQFTSWPELGLPESKSNLIRFIQEVHGHYLLQRPLHTPVVVHCSSGVGRTGAFCLLYAALQEIEAGNGIPDLIQLVRKMRQQRKNMLQEKLHLKFCYEAVLKHTEQVLQRHGIITSPCTRTPNNITLKSYSRQESQDIVLGGDMPISSIQATVAKLSIRPPSVDHEQEPSQDQMPFTSEVAGLGEPDPTDVPLQPSQDPLCCETMPDSISPPLSCTSSPGKTQSPSPPSGQGNGFNGSTPASPVSNHHPSNEATPRGPSPPTSSSLDLLASLTPEAFTLDSAHRGKQRINKQSFLQPQEGKGLQGPPEGDDPLSSLDPLWTLNKS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******************:*:*..:**:*:******:*: ***:***** ***.*:.*.*******.****:***********:* ******.::********:*:**** *********************:****************:********:**.:::*****:***.**:*********************************************.:***:**:******************:**************:******:**:****.***********:**:****:*******:*************:**:*:** .********.********:*******************************:::**:::***.*:*****: ****:***:: *. :*. ***************:**:*****************::***:*:*** **.::*::*: .. : ***:**: **:*.********:*********:.*****.**** :* *** * *: :: * **.:****.********* ***:***:***:****::****::::************:*:***::******:.:* **********:**: *:: ::*****:* ******************::** ***:*.: ***:::: *:*:: ** : :****** .* ******* : :: * .* ** *********:: * : *: :.**: **.. * . ** .:.*.. . . * *: .:* .* . :* *: . ..: * *:. . :.:* .. .*. . . :** *.***:: *.: :*... :. ** ..*. *:* :* * * . :* .** . * * .* *:* .* ... *:. *.* . * ... :*** * :** *.* * * * :.*::*.: *. ** * : :*.. .* *.*: * .. .** . *..:.**. * *: *.* .**.:*: ** * :: *.... :*.**::*******.*.* *. **..* .* *:.::: **************: . :* ***.*. * ::.:.:***: ***: ***: :*. :** **. *. . **: *:***: **:*:* ********::***********.*****:********** .*.****** *:******.**********:************* *:***** ****:**** :.:*.::::*:: ::* **:**::.**:*****:*::***:*.:*******:* .**:*******.*** *******::*************.*****:**:*******:* ****:******:********:**:**:::*.********: .. . :. .*: *.: *:***:*****:********:******* : * .*.* *. .: * *. . . .:*.* .****.. * :* .:..*. :* . *.****:**********:***: *****:.*:.***.::*:**:.. ***** *********:", "identical_positions": 989, "similar_positions": 395, "identity": "49.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97924-1", "uniprot_id": "KALRN_RAT", "id": "P97924-1", "name": "Kalirin", "aln": "------------------MVLSGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTFPARTNHDRIRQEDLRKLVTNLASVPSEDVCKRGFTVIIDMRGSK--WDLIKPLLKTLQEAFPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKAPVEELDREGQRLLQCIRCSDGFSGRN---------------------------CIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQHALDLQTQHNHFAMNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVFHQKAEQFLSGVDAWCKMCSEGG-LPSEMQDLELAIHHHQSLYEQVTQAYTEVSQDGKALLDVLQRPLSPGNS---------------------ESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDLQKEVLEDVCADS---VDAVQELIKQFQQ-QQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPTEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIMEVQASGIELICEKDVDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIE---------KTHQSALQVQQKAEALLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYRRDEDWCGGRDKLGPAAEMDHVIPLLSKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQETGEYYLSTHT-STGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYTLEKALGVNTE---DNKDLELDIIPASLSDR-----EVKLRDAN---HEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRVTKYQLLLKELLTCCEEGKGELKDGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPS-SDNKTVLKASNIETKQEWIKNIREVIQERIIHLKGALKEPIQLPKTPAKLRNNSKRDGVEDGDSQGDGSSQPDTISIASRTSQNTVESDKLSGGCELTVVLQDFSAAH-SSELSIQVGQTVELLERPSE-RPGWCLVRT---TERSPPQEGLVPSSTLCISHSRSSVEMDCFFPLVKDSYSHSSGENGGKSESVANLQSQPSLNSIHSS-PGPKRSTNTLKKWLTSPVRRLNSGKADGNIK-KQKKVRDGRKSFDLGSPKPGDETTPQGDSADE-------KSKKGWGEDEPDEESHTPLPPPMKIFDNDPTQDE-MSS-LLAARQAPTDVPTAADL----VSAIEKLVKSKLTLEGGSYRGSLKDPTVCLNEGMAPPTPPRNLE----EEQKAKALRGRMFVLNELVQTEKDYVKDLGIVVEGFMKRIEEKG----VPEDMRG-KEKIVFGNIHQIYDWHKDFFLAELEKCIQEQDRLAQLFIKHERKLHIYVWYCQNKPRSEYIVAEYDAYFEEVKQEINQRLTLSDFLIKPIQRITKYQLLLKDFLRYSEKAGL--ECSDIEKAVELMCLVPKRCNDMMNLGR-LQGFEGTLTAQGKLLQQDTFYVIELDAGMQSRTKERRVFLFEQIVIFSELLRKG--SLTPGYMFKRSIKMNYLVLEEDVDDDPCKFALMNRETSERVILQAANSDIQQAWVQDINQVLETQRDFLNALQSPIEYQR-KERSTAVIRSQPPRVPQASPRPYSSVPVGSEKPPKGSSYNPPLPPLKISTSNGSPGFDYHQPGDKFDASKQNDLGGCNGTS-TMAVIKDYYALKENEICVSQGEVVQVLAVNQQNMCLVYQPASDHSPAAEGWVPGSILAPLTKATAPAESSDESIKKSCSWHTLRMRKRADVENT----GKNEATGPRKPKDILGNKASVKETNSSEESECD-DLDPNTSMEILNPNFIQEVAPEFLVPLVDVTCLLGDTVLLQCKACGRPKPTITWKGPDQNILDTDNSSATYTISSCDSGESTLKICNLMPQDSGIYTCIATNDHGTASTSATVKVQGVPAAPNRPIAQERSCTSVILRWLPPASTGNCTISGYTVEYREEGSQVWQQSVASTLDTYLVIEDLSPGCPYQFRVSASNPWGISLPSEPSEFVHLPEYDAAADGATISWKENFDSAYTELNEIGRGRFSIVKKCIHKATRKDVAVKFVSKKMKKKEQAAHEAALLQHLQHPQYVTLHDTYESPTSYILILELMDDGRLLDYLMNHDELMEEKVAFYIRDIMEALQYLHNCRVAHLDIKPENLLIDLRIPVPRVKLIDLEDAVQISGHFHIHHLLGNPEFAAPEVIQGIPVSLGTDIWSIGVLTYVMLSGVSPFLDESKEETCINVCRVDFSFPHEYFCGVSNAARDFINVILQEDFRRRPTAATCLQHPWLQPHNGSYSKIPLDTSRLACFIERRKHQNDVRPIPNVKSYIVNRVNQGT------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2CG49-1", "uniprot_id": "KALRN_MOUSE", "id": "A2CG49-1", "name": "Kalirin", "aln": "------------------MVLSGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSK--WDLIKPLLKTLQEAFPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKAPVEELDREGQRLLQCIRCSDGFSGRN---------------------------CIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQHALDLQTQHNHFAMNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVFHQKAEQFLSGVDAWCKMCSEGG-LPSEMQDLELAIHHHQSLYEQVTQAYTEVSQDGKALLDVLQRPLSPGNS---------------------ESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDLQKEVLEDVCADS---VDAVQELIKQFQQ-QQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPTEARDSAMSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYIMEVQASGIELICEKDLDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIE---------KTHQSALQVQQKAEALLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYRRDEDWCGGRDKLGPAAEMDHVIPLLSKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQETGEYYLSTHT-STGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTE---DNKDLELDIIPASLSDR-----EVKLRDAN---HEINEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRVTKYQLLLKELLTCCEEGKGELKDGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPS-SDNKTVLKASNIETKQEWIKNIREVIQERIIHLKGALKEPIQLPKTPAKLRNNSKRDGVEDGDSQGDGSSQPDTISIASRTSQNTVESDKLSGGCELTVVLQDFSAGH-SSELSIQVGQTVELLERPSE-RPGWCLVRT---TERSPPQEGLVPSSALCISHSRSSVEMDCFFP-LKDSYSHSSSENGGKSESVAHLQSQPSLNSIHSS-PGPKRSTNTLKKWLTSPVRRLNSGKADGNIK-KQKKVRDGRKSFDLGSPKPGDETTPQGDSADE-------KSKKGWGEDEPDEESHTPLPPPMKIFDNDPTQDE-MSS-LLAARQAPPDVPTAADL----VSAIEKLVKNKLTLEGGSYRGSLKDPTGCLNEGMTPPTPPRNLE----EEQKAKALRGRMFVLNELVQTEKDYVKDLGIVVEGFMKRIEEKG----VPEDMRG-KEKIVFGNIHQIYDWHKDFFLAELEKCIQEQDRLAQLFIKHERKLHIYVWYCQNKPRSEYIVAEYDAYFEEVKQEINQRLTLSDFLIKPIQRITKYQLLLKDFLRYSEKAGL--ECSDIEKAVELMCLVPKRCNDMMNLGR-LQGFEGTLTAQGKLLQQDTFYVIELDAGMQSRTKERRVFLFEQIVIFSELLRKG--SLTPGYMFKRSIKMNYLVLEDNVDGDPCKFALMNRETSERVILQAANSDIQQAWVQDINQVLETQRDFLNALQSPIEYQR-KERSTAVIRSQPPRVPQASPRPYSSGPVGSEKPPKGSSYNPPLPPLKISTSNGSPGFDYHQPGDKFDASKQNDLGGCNGTS-TMTVIKDYYALKENEICVSQGEVVQVLAVNQQNMCLVYQPASDHSPAAEGWVPGSILAPLAKATAAAESSDGSIKKSCSWHTLRMRKRADVENS----GKNEATGPRKPKDILGNKVSVKETNSSEESECD-DLDPNTSMEILNPNFIQEVAPEFLVPLVDVTCLLGDTVLLQCKACGRPKPSITWKGPDQNILDTDNSSATYTISSCDSGESTLKICNLMPQDSGIYTCIAANDHGTASTSATVKVQGVPAAPNRPIAQERSCTSVILRWLPPASTGNCTISGYTVEYREEGSQVWQQSVASTLDTYLVIEDLSPGCPYQFRVSASNPWGISLPSEPSEFVRLPEYDAAADGATISWKENFDSAYTELNEIGRGRFSIVKKCIHKATRKDVAVKFVSKKMKKKEQAAHEAALLQHLQHPQYVTLHDTYESPTSYILILELMDDGRLLDYLMNHDELMEEKVAFYIRDIMEALQYLHNCRVAHLDIKPENLLIDLRIPVPRVKLIDLEDAVQISGHFHIHHLLGNPEFAAPEVIQGIPVSLGTDIWSIGVLTYVMLSGVSPFLDESKEETCINVCRVDFSFPHEYFCGVSNAARDFINVILQEDFRRRPTAATCLQHPWLQPHNGSYSKIPLDTSRLACFIERRKHQNDVRPIPNVKSYIVNRVNQGTSLSHNP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60229-1", "uniprot_id": "KALRN_HUMAN", "id": "O60229-1", "name": "Kalirin", "aln": "MTDRFWDQWYLWYLRLLRLLDRGSFRNDGLKASDVLPILKEKVAFVSGGRDKRGGPILTFPARSNHDRIRQEDLRKLVTYLASVPSEDVCKRGFTVIIDMRGSK--WDLIKPLLKTLQEAFPAEIHVALIIKPDNFWQKQKTNFGSSKFIFETSMVSVEGLTKLVDPSQLTEEFDGSLDYNHEEWIELRLSLEEFFNSAVHLLSRLEDLQEMLARKEFPVDVEGSRRLIDEHTQLKKKVLKAPVEELDREGQRLLQCIRCSDGFSGRN---------------------------CIPGSADFQSLVPKITSLLDKLHSTRQHLHQMWHVRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQYALDLQTQHNHFAMNSMNAYVNINRIMSVASRLSEAGHYASQQIKQISTQLDQEWKSFAAALDERSTILAMSAVFHQKAEQFLSGVDAWCKMCSEGG-LPSEMQDLELAIHHHQTLYEQVTQAYTEVSQDGKALLDVLQRPLSPGNS---------------------ESLTATANYSKAVHQVLDVVHEVLHHQRRLESIWQHRKVRLHQRLQLCVFQQDVQQVLDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDLQKEMLEDVCADS---VDAVQELIKQFQQ-QQTATLDATLNVIKEGEDLIQQLRSAPPSLGEPSEARDSAVSNNKTPHSSSISHIESVLQQLDDAQVQMEELFHERKIKLDIFLQLRIFEQYTIEVTAELDAWNEDLLRQMNDFNTEDLTLAEQRLQRHTERKLAMNNMTFEVIQQGQDLHQYITEVQASGIELICEKDIDLAAQVQELLEFLHEKQHELELNAEQTHKRLEQCLQLRHLQAEVKQVLGWIRNGESMLNASLVNASSLSEAEQLQREHEQFQLAIESLFHATSLQKTHQSALQVQQKAEVLLQAGHYDADAIRECAEKVALHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYRRDEDWCGGRDKLGPAAEIDHVIPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSMPSVASHTRGPEQQVKAILSELLQRENRVLHFWTLKKRRLDQCQQYVVFERSAKQALDWIQETGEFYLSTHT-STGETTEETQELLKEYGEFRVPAKQTKEKVKLLIQLADSFVEKGHIHATEIRKWVTTVDKHYRDFSLRMGKYRYSLEKALGVNTE---DNKDLELDIIPASLSDR-----EVKLRDAN---HEVNEEKRKSARKKEFIMAELLQTEKAYVRDLHECLETYLWEMTSGVEEIPPGILNKEHIIFGNIQEIYDFHNNIFLKELEKYEQLPEDVGHCFVTWADKFQMYVTYCKNKPDSNQLILEHAGTFFDEIQQRHGLANSISSYLIKPVQRITKYQLLLKELLTCCEEGKGELKDGLEVMLSVPKKANDAMHVSMLEGFDENLDVQGELILQDAFQVWDPKSLIRKGRERHLFLFEISLVFSKEIKDSSGHTKYVYKNKLLTSELGVTEHVEGDPCKFALWSGRTPS-SDNKTVLKASNIETKQEWIKNIREVIQERIIHLKGALKEPLQLPKTPAKQRNNSKRDGVEDIDSQGDGSSQPDTISIASRTSQNTVDSDKLSGGCELTVVLQDFSAGH-SSELTIQVGQTVELLERPSE-RPGWCLVRT---TERSPPLEGLVPSSALCISHSRSSVEMDCFFPLVKDAYSHSSSENGGKSESVANLQAQPSLNSIHSS-PGPKRSTNTLKKWLTSPVRRLNSGKADGNIK-KQKKVRDGRKSFDLGSPKPGDETTPQGDSADE-------KSKKGWGEDEPDEESHTPLPPPMKIFDNDPTQDE-MSSSLLAARQASTEVPTAADL----VNAIEKLVKNKLSLEGSSYRGSLKDPAGCLNEGMAPPTPPKNPE----EEQKAKALRGRMFVLNELVQTEKDYVKDLGIVVEGFMKRIEEKG----VPEDMRG-KDKIVFGNIHQIYDWHKDFFLAELEKCIQEQDRLAQLFIKHERKLHIYVWYCQNKPRSEYIVAEYDAYFEEVKQEINQRLTLSDFLIKPIQRITKYQLLLKDFLRYSEKAGL--ECSDIEKAVELMCLVPKRCNDMMNLGR-LQGFEGTLTAQGKLLQQDTFYVIELDAGMQSRTKERRVFLFEQIVIFSELLRKG--SLTPGYMFKRSIKMNYLVLEENVDNDPCKFALMNRETSERVVLQAANADIQQAWVQDINQVLETQRDFLNALQSPIEYQR-KERSTAVMRSQPARLPQASPRPYSSVPAGSEKPPKGSSYNPPLPPLKISTSNGSPGFEYHQPGDKFEASKQNDLGGCNGTS-SMAVIKDYYALKENEICVSQGEVVQVLAVNQQNMCLVYQPASDHSPAAEGWVPGSILAPLTKATA-AESSDGSIKKSCSWHTLRMRKRAEVENT----GKNEATGPRKPKDILGNKVSVKETNSSEESECD-DLDPNTSMEILNPNFIQEVAPEFLVPLVDVTCLLGDTVILQCKVCGRPKPTITWKGPDQNILDTDNSSATYTVSSCDSGEITLKICNLMPQDSGIYTCIATNDHGTTSTSATVKVQGVPAAPNRPIAQERSCTSVILRWLPPSSTGNCTISGYTVEYREEGSQIWQQSVASTLDTYLVIEDLSPGCPYQFRVSASNPWGISLPSEPSEFVRLPEYDAAADGATISWKENFDSAYTELNEIGRGRFSIVKKCIHKATRKDVAVKFVSKKMKKKEQAAHEAALLQHLQHPQYITLHDTYESPTSYILILELMDDGRLLDYLMNHDELMEEKVAFYIRDIMEALQYLHNCRVAHLDIKPENLLIDLRIPVPRVKLIDLEDAVQISGHFHIHHLLGNPEFAAPEVIQGIPVSLGTDIWSIGVLTYVMLSGVSPFLDESKEETCINVCRVDFSFPHEYFCGVSNAARDFINVILQEDFRRRPTAATCLQHPWLQPHNGSYSKIPLDTSRLACFIERRKHQNDVRPIPNVKSYIVNRVNQGT------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z2L7-1", "uniprot_id": "A0A8M6Z2L7_DANRE", "id": "A0A8M6Z2L7-1", "name": "non-specific serine/threonine protein kinase", "aln": "MNSAEAPEDGPNDSDTDAFFKTGSFRSEGIKASDVLPVLREKIAFVSGGRDKRGGPILTFPARSNHDRIKQEDLRRLVTYLSTVPSEDVCKRGFTVIIDMRGSK--WELIKPLLKTLQEAFPAEICVALIIKPDNFWQKQKTNFGSAKFTFETSMVSVEGLTKLVDPSQLTDDFEGSLEYNHEEWLELRVALEEFLASAVHLLSRLEDLQETLAKKEFPVDVEGSRRLIDEHTQLKKKVMKAPVEELDHEGQRLLQCIRSSDGFSGRN---------------------------CISGSADFQSVVPKIASLLDKLHSTRQHLHQMWHLRKLKLDQCFQLRLFEQDAEKMFDWISHNKELFLQSHTEIGVSYQHAVELQTQHNHFAMNSMNAYVNINRIMSVASRLSEAGHYAAQQIKQISTQLDQEWKSFAAALDERSTILAMSAVFHQKSEQFLSGVETWCKMCSEGG-LPSEMQDLESAIHHHQTLYEQVTQAYTEVSQDGKALLDVLQRPLSPGNA---------------------ESLTATANYSKAVHCILDVVHEVLHHQRRLENIWQHRKVRLHQRLQLCVFQQDVQQVIDWIENHGEAFLSKHTGVGKSLHRARALQKRHDDFEEVAQNTYTNADKLLEAAEQLAQTGECDPEEIYKAARHLEVRIQDFVRRVEQRKLLLDMSVSFHTHTKELWTWMEDLQKELLEEVCSDS---VDSVQELIKQFQQ-QQTATLEATLNVIKEGEDLMQQLR-------------DSAMSSNKMPHTSSIAHIEGVLQQLEEAQGHMEELFHERKIKLDIFLQLRIFEQYTIEVTAELDAWNEDLVRQMNEYTGEEPSLAEQRLQRHAERKLAMTNMTYEVMQQGQDLHQYIMEVQASGIELTGEKEVDLATQVQELLEFLHEKQHELDMSAEHTQKRLEQCVQLRHLQAEVKQVLGWIRNGESMLDASMVNASSLSEAEQLQREHEQFQLAIESLFHANSLQKTHQSALQVQQKAEIMLQAGHFDPEAIRSCAEKVAVHWQQLMLKMEDRLKLVNASVAFYKTSEQVCSVLESLEQEYRRDEDWCGAHDKLGSSSETDHVLPLISKHLEQKEAFLKACTLARRNAEVFLKYIHRNNVSSQGSSSNTRGPEQQVKAILNELLQRENRVLHFWTMKKRRLDQCQQYVVFERNAKQALEWIEEAGEVYLATHT-CIGDSMEKTQGLLKEYEEFCISAKQTKEKVKMLIQLADNFVEKGHMHVTDLKKCLTAVDKRYRDFSMRMGKYRCDLENVLGISSE---DNKDLELDIIPASLTGP-----EVKLRDPN---HEVNEEKRKSARKKEFIIAELLQTEKAYVRDLHECLETYLWEMTNGVEEIPPGIANKEHIIFGNIQEIYDFHNNIFLKELINYEQLPEDVGHCFVTWADKFNIYVTYCKNKPDSSQLILDHAGSFFDEIQKRHSLTNSISSYLIKPVQRITKYQLLLKELLSCCEEGKGEIKDGLEVMLSVPKRANDAMHVSMLEGFDANLDVQGELILQDTFQVWDPKSLIRKGRDRHLFLFEISLVFSKEIKDSAGRSKYIFKNKLLTSELGVTEHVEGDPCKFALWVGRTPS-SDNKTVLKASSIEVKQEWIKNIREVIQERIIHLKGALKEPIHIPKTPAKPRNNSKRDAGEDADSQGDGSSQPDTISIASRTSQNTVDSDKLSGGCELTVVLQDFTASS-SSELSIQTGQTVELLERPSD-RPGWCLVRT---TEKTPPQEGLVPSSALCISHSRSSVEMDCFFPAGKENYTVSGPE--GKTESVATLQPQPSLNSLQSSSPGPKRSGNTLKKWLTSPVRRLSHGSNIKKIPSKQKQKRDGRKSIDMGPPELQDDTLEERVQKEEGTLSKSSSGMHSGGEEEPEDESHTPLPPPMEIIKDPSAQEE-KSSVLLASRQSSADVPSAAEL----VSAIEKLVKTKMTLEPGSYPG-----FSSVNPAEQSPIPPRNPE----LEQKAKALRGRMFVVKELIQTEKDYVKDLGIVVEGFMKRIEEKG----VPDNMKG-KDKIVFGNIHQIYDWHKDFFVGELEKCLEDHEKLPELFCKHERRLHMYVVYCQNKPKSEFIVAEYDSYFEGIQQDINSRLSISDFLIKPIQRITKYQLLLKDVLKYSTKAGL--DCQDIENAVDLMSQVPKLCNDMMNLGR-LQGYEGKLTSQGKLLQQETFFVTEQDSGVLSRSKERRVFLFEQIVIFSELLRKG--SSTPGYQFKKSIKVSFLDLEEHVENDPCKFVLSCRGSAERFTLQAANTDIKQVWVQHITQLLDLQSNFLSALQSPIEYQKERSGSQSLTRNSSGRMGQSNSRPCSTVSLGAEKP---SLSGRSSTPLKLSTSNGGPCSERYR--------RQFEGLGCNGTSSSLMVTQDYTALKENEICVTQGEAVQVLATNQQNMYLVYRPANSQSPPAEGWVPGHILGPVTKPLI-DTTADASIKKSLSWNTLRARKRAEKDSTPLKSDFKVENGLRKPKEILSSKVKVKESRSSDESECEDELDPKTSMELLNPNFIQEVAPEFLTPLTDVTCALGETVVLCCKVCARPKPTITLKGPDQSLLANNNR---FTINIRETGDIVLKICNLMPQDTGIYTCVAVNDHGTASSSASIKVQGIPAAPARPVAQEASSTAVIVHWLPPASSANSAISSYTVEYRQEDSLVWQQLVVSTADVCVKIDNLIPGGHYQFRVSASNPWGTSPPSEPSNMVTLSSTASTYDGAGIQWKDNFESAFTELCEIGRGRFSVVRKCLSKATKQEVAVKFVNKKMHKKEQVAHEADILRHVQHPQLVSLIDTYESPTAYMLILELVEDGRLLDYLVAHDELMEEKVAFFIKDTLEALQHLHTCRVAHLDLKPENLLVDLHVPVPCVKLSDLGDAVQVSSHRYVHLLLGNPEFAAPELIQGTPVSLSTDVWSVGVLAYVMLSGVSPFLDESLEETCVNICRLDFCFPQEYFSDISQAAKDFIVSTLNQDPRKRPSSASCLQHPWVSAHSGDYSKAPLDTVRLAAFIDRRKQLHDVRPVTNIKGMVSSSMGHTL------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KVD1-1", "uniprot_id": "Q7KVD1_DROME", "id": "Q7KVD1-1", "name": "", "aln": "--------------------------MDGQRARDLLTLLQERVVFLTGGRDRRGGPLLCFPATPRRDRLKPEDLRRLLSYLISIPSDAAKNLGFTVIIDMRGNGNCSTNVKTILKVLQEHFSANIHNVVIIKPDNFWQKQRASISSHKYKFETTTVSIESLNKIVESHQLTGDFEGQQLYDHQQWTDARLAIEDFFWQAGDMADRIDDLQEDLNRNDFAEDVPLARHAIDHHNEMRKKITKLPIEDLDMQGKKLLAKINAMAPPGGQAPTNSGGPDMDSGPSSAGQQSQPSQQSRSVGGNPDMSAAVNKALRQIELIHTGQEKLLMLWQHKKVKLDQCFQWRLFEQDCEKMFDWILHNRDVFQMSYVEIGHNYSVAKSLQDEHQKFAVASMNVSVNIDRILAVAARLIESQHYAAQHIKTLAQRLDRTWKDFAAGLDERTAVLQLSVLFHHKAEQYCNSVASWAAACQASQPLPSDIQSLETAIRTHQSLYEAMCQAYTEVHSTSKKLLYQLDHLVQVCNQPPPPGVPDHRKNSNNGSFNKYERQNPAADYSEGASHVLAVIHQILSHHRTLEAKWHQERLRLHQTLALRLFQEDVKQVLDWLKNHGEVFLRKNTGIGRNFHKARVYQTSHDNFENVAQNTYSNAQKLLAAADELARSGEADPNEIYSVARELELQVGSFAERVEQRRRRLDMAVIFYTHEKDVTAWIDKLRTDVSTDETRLSQENLEGIERILQQYQRDQQESSVNVCLTTISQGEALLQEMR-----------------SLEYADNTGSIAALEATLEKLNKQKVELEELWSARKFRADLILRLRYFERDARLLSVQMEMWSEELQHAD---LSRDYQKAEQLIRMHNESVTEIQNATYEVVQQGQDLLQLFEN---AGFISMADATHTAQARIEYLLDFLREREIDLEEMSEAKRAKLEQAVQLCQFQNDANQVISWIRNGEAMLVASFVTPNSLQEAEQLRKGHEQFQIAIE---------KTHTSAVQVKYRADALINANHYDPLSIDEISDDVTKKWQQLVTYAEERHKLVTASINFYKTAEQVCSVLDSLEREYKREDDWCDGG---GGSDKAQAIVQLISKHQEQKEAFLKACTLARRTAETFLKYANR----SQQCYQYKGNCEGHVKSKLDKLLTQENQVLDYWTLRKKSLDQCQQFVLFERSAKQAIEWIHNTGEAYLSSRSNLVGISKEETEGLLKEHNEFRSTAKETRERVKLLIQLADSLVEKGHAHASDIKQWVASVDQRYKDFSNRMDSYCEQLEKSLGMSQQQLLLGSDGNSSISSSSGDRHSDPTLEAKLNSSNKENKEINEEKRKSARRKEFIMAELMQTERAYVNDLATCIKCFLEEFRAG-KSVPSALIGQEDVIFGNIKEIHHFHQKIFLRELEKYETMPEDVGHCFVTWASKFDMYVHYCKNKPTSNNLLVQHGGSFFEELQRRLEVDHPLPAYLIKPVQRITKYQLLLKDLLSCCEESHGEIKEGLEVMLNVPKKANDAMHLSLLENCDVSVDKLGEVVLQDAFQAWDTKQIIRKGRERRVFLFELYLLFAKEVKESN-VVKYQFKSKLMTTDMGITEHIEGDETKFAVWTGRSPMLSDCRIVLKATSLETKQIWVKKLREVMQETCFSGT-----SLTLPKSPAKHSGSSQR-SSRDLDEQLTEN-DHDRCSLASFGSGNTTDSDNKLGNQEATWVVADYIATSGSNELSVSKGQQVEIVEPPTAGEPDFCLVRLNPQHDDAAVQEGLVPVSVLKPPPGSHKHGSGTAANAASSAGSQKSDMQDQSNRSKADALSSSTKRRGFSG-RNWLPLMNRKGTDKPPSSKPLVKKPSEKNLRTPQKHAEELAEQQNQQPGASPATVLPSSQFPSS----TQHPGGAGAGDYEPDEEVGLELPPPMKPIQEPHLIANGPPAFAKDAKESSGNMASPGKMDGNPLSEIEEIVKTTTEQHESNSRVDGGGGVENASTNGHGRSHDNNDESHTAVSDKAAALKKRQCVFAELMSTEEAYVQDLHEIVNGYMTEINNTNSDIPMPEDLKGGKMKLVFNNIKDIYEWHRDFFLRALRNCQKSPADLGPLIKRSATKFALYYTYCSNKPLSEYIVSAHYQYFDSIRQKLGHRLDLSNLIIKPVQRITKYELLIKEIIKATEGAGLYKEVPMLQEAYQQMKVVVKTVNDMMVVLRSLQDFDGEITAQGSLLMQGPMNCVVDAA---QKHRELQVFLFQQIIIFADIEKTKNQYASPIFKYRSHIQLNHMQMKELGDCRFQIRSTDPKIPEMTIICQAASQENYAGWRDMLNKILQQQNDLIFMLSNPLSTKN-K-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :* *:*.:*:*::.*::****:****:* *** ..:**:: ****:*:: * ::**: . : **********. :*.:**.*** *.*:* .:***********::.:.* *: ***: **:*.*.*:*:. *** :*:*. *:*::* : *:::*:*: .* .: .*::**** * :::*. ** :*: **.*.:::**: * *:*:** :*::** *.. .*: .: *..*:.: * * :: :*: :::* :*: :*:******* ******.******* **:::* *:.*** .*. * .** :*::**: ***. ***:**::**:** *: ***:*:** :: :**: **.***.****:::* :*.:**:*:**: ..* :*. *. . ***::*.** **: **:*** : ****** . .* ** *:: :. * * ..:*:**:.. :* *:*::* *:* ** *::.::**** * * :**:**:**:**::****.** *:**:*:.:*:**. *. **:**:******:**:*** **::**::**.**:***..**.**::: .*..*****: ***:* *:** *:: :*::.*:.:: : * ::.::.:::*:*: ** ::::. *..*.:** *:*::* * : ::.**: :*..*::*:. : .:***: **:: *::*:** **: : ::.::: *.*:* : .: *** :: * * : * *:**:****** * : : :*: : :::: **:**:*:: :*: :* .: :***.:** ::* :.:**:.******:** **:*...**.*****:: *****:*** *** **:**: :*: :::*.*:*. :* . ::.*: :****: *:* ***.**: ****:*******:***:**:*::***.. * : : : :: *:*** ***************.**.**** :* . . . * :**: *.:** :**:**.:**::*: ******:*:***.****::**.::** **:::: * : *:*: ****: ** .**:*:*:**:******.:***** *.::::: :::**::*:*** **..* **: **:. : ..* : .* .:* *.**...* :*:*********:****:***:***:***.** *:: :* *: * :.:*..: .:*.:*****:**:.**::***:** :** :************.**::** ****** *.:*:::*.*:**:*:*:* : :.:.:********:********:**:****.:**:*:******.***:******:*:**. * .:* **::***:**.**.*.:*****:*::****: *:*:**:*:* ** :*.**:*:::*:***:*** ***:* **:* ** : ****:.:*.** *:*::***:** : . .: :**:*** ..*:* . .* *.* . : * *:** * **.:**: *. * * *: *: * *.**::. ** **::* *: .*.:**** : :. ***** *.* . . . . .. : .. ...* * ...: . *. . * . ... : * :: **: .: :. : . . . .. . . *: **::* *****: :.: : .: ::::. ::.:...: :. **::**.. . .. . .* * .:** **: * *. **:.**: **:** :*:*:*..*::.. :*::::* * *:**.**::**:**:***: *.:* :. * *: : :: :* **.*** **:**: : **: ::*.:. ** :*:::***:******:**:*:.:: : *** : :::* : * * * **** : * **.::* :*:**.** * .: : .: :* :****:**:**::: :. :* : :: *::..: ::: : : . . ***. : * : :.::*: * ::: *..*:. :. : ", "identical_positions": 899, "similar_positions": 750, "identity": "28.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-43", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZZE0-1", "uniprot_id": "A0A8I5ZZE0_RAT", "id": "A0A8I5ZZE0-1", "name": "Bromodomain and WD repeat-containing protein 3", "aln": "---MAAAP-TQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKNTLWNGSAFAALHRGRPPELPVNYVKPPNVVNITSARQLTGCSRFSHVFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTTRYLTSTGADGTICFWQWHVKT---MKFRDRPVKFTERSRPG-VQISCSSFSSGGMFITTGSTDHVIRIYYLGSEIPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMSGNNLTSTEDKVTKLKVTMVAWDRYDTTVITAVNNFLLKVWNSVTGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFG-CSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENCKDEQLIPQL-----GYVANGDGEVVEQVIGQQTND----------------QEESILDGIIRELQREQ-------DLRLINEGDVPHFPINRSYSVNGALSSPNMDIPSSPNIGLRR-SGQIEGVRQMHNNAPRS----------QMATERDL-MAWSRRVVVNELNSGVSRVQEECRNAKGDLEVSLYTVEKKKK--PSYPIQRNDYQP--SCGRSL--------RRTQRKRQHTYLTRSNIEHNSQASSQ----NSGVQGDSDSSSEEDETVGTSDASAEDPVVEWQSESSSSDS---SSEYSDWTADA-GINLQPPKRQTRQATQKIYSSSEDE----NVKSSEDRQKKPKQTRKKKGGL--VSMAGEPNEEWLAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPWNKMDLREQEFVKIVGIKYEIGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPEGTAFPDEVGAGIPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINNLLSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIKQRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIGDQSCTDILDTYNKIKAEN-PNSSDPEEDTEMVDLDSDGPGTSSG----RRAKCRGRRQSLKCNPDAWKQQCKELLSLIYEREDSEPFRQPADPHSHPAQQQ-EGESSESVPPDRQ-DPSLSEDYQDVVDTPMDFSTVKETLESGNYDSPLEFYKDVRQIFSNSKAYTSNKKSRIYSMTLRLSALFENRIKNIISEYKSAIQ---------------------------------SQK------------------------------------RRRPRYRKRLRSSSSSLSSSRAPSP-KGKQKQMKLQPKNDQNTSVVYARTSSPFSSPVSDAAEG-------------VSLYLLDDEGDGPFSPSSCSGYSRSGNSHDPGKAKSFRNRVLP---AKQDHSLDGPLTNVDGREPRTGAKRKLLSASEEDESMGGEEKEMKETKE---KAHLSSSESGELGSSLSSESTSGSDSDSEST------SRTDQDYVDG-DHDYSKFIQT-------------RPKRK------------------------------------LRRQHATGKRNWKTRGTGGRGRWGRWGR----------------------------------------------------------------------------WSRGGRG----------------------------------------------------------------------RGGRGRGGRG----RGGGGGRGRGRGRGGRGASRGASRTKRARVADDEFD----TMFAG------RFSRLPRIKTRNQGR-----------RTVLYNDDSDNDNFVSTEDPLNLG-TSRSGRVRKMTEKARVS----HLMGWNY---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AHJ4-1", "uniprot_id": "BRWD3_MOUSE", "id": "A2AHJ4-1", "name": "Bromodomain and WD repeat-containing protein 3", "aln": "---MAAAP-TQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKSTLWNGSAFAALHRGRPPELPVNYVKPPNVVNITSARQLTGCSRFSHVFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTTRYLTSTGADGTICFWQWHVKT---MKFRDRPVKFTERSRPG-VQISCSSFSSGGMFITTGSTDHVIRIYYLGSEIPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMSGNNLTSAEDKVTKLKVTMVAWDRYDTTVITAVNNFLLKVWNSVTGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFG-CSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENCKDEQLIPQL-----GYVANGDGEVVEQVIGQQTND----------------QEESILDGIIRELQREQ-------DLRLINEGDVPHFPINRSYSVNGALSSPNMDIPSSPNIGLRR-SGQIEGVRQMHNNAPRS----------QMATERDL-MAWSRRVVVNELNSGVSRVQEECRNAKGDLEVSLYTVEKKKK--PSYPIQRNDYQP--SCGRSL--------RRTQRKRQHTYLTRSNIEHNSQASSQ----TSGVQEDSDSSSEEDETVGTSDASVEDPVVEWQSESSSSDS---SSEYSDWIADA-GINLQPPKRQTRQATQKIYSSSEDE----NLK-LEDRQKKPKQTKKKKGGL--VSMAGEPNEEWLAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPWNKMDLREQEFVKIVGIKYEIGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPDGTAFPDEVGAGIPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINNLLSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIKQRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIGDQSCSDILDTYNKIKAED-PDSSDLEEDSEMVDLDSDGPGTSSG----RRAKCRGRRQSLKCNPDAWKKQCEELLSLIYEREDSEPFRQPADPQSYPVQQQQEGESSQSVPPDRQ-DPSLSEDYQDGIDTPMDFSTVKETLESGNYDSPLEFYKDVRQIFSNSKAYTSNKKSRIYSMTLRLSALFENHIKNIISDYKSAIQ---------------------------------SQK------------------------------------RRRPRYRKRLRSSSSSLSSSRAPSP-KGKQKQMKLQPKNDQNTSVAYARTSSPFSSPVSDAAEG-------------VSLYLLDDEGDGPFSPSSFSGYSRSGNSHDPGKAKSFRNRVLP---AKQDHSLDGPLTNVDGREPRTGAKRKLLSASEEDESMGGEEKEMKETKE---QVHLSSSESGELGSSLSSESTSGSDSDSEST------SRTDQDYVDG-DHDYSKFIQT-------------RPKRK------------------------------------LRKQHTNGKRNWKTRGTGGRGRWGRWGR----------------------------------------------------------------------------WSRGGRG----------------------------------------------------------------------RGGRGRGGRG----RGGGGGRGRGRGRGGRGASRGSSRAKRARVADDEFD----TMFSG------RFSRLPRIKTRNQGR-----------RTVLYNDDSDNDNFVSTEDPLNLG-TSRSGRVRKMTEKARVS----HLMGWNY---------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6RI45-1", "uniprot_id": "BRWD3_HUMAN", "id": "Q6RI45-1", "name": "Bromodomain and WD repeat-containing protein 3", "aln": "---MAAAP-TQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKSTLWNGSAFAALHRGRPPELPVNYVKPPNVVNITSARQLTGCSRFGHIFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKT---MKFRDRPVKFTERSRPG-VQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMTGNNLPSGEDKITKLKVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFG-CSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENCKDEQLIPQL-----GYVANGDGEVVEQVIGQQTND----------------QDESILDGIIRELQREQ-------DLRLINEGDVPHLPVNRAYSVNGALRSPNMDISSSPNIRLRRHSSQIEGVRQMHNNAPRS----------QMATERDL-MAWSRRVVVNELNNGVSRVQEECRTAKGDIEISLYTVEKKKK--PSYTTQRNDYEP--SCGRSL--------RRTQRKRQHTYQTRSNIEHNSQASCQ----NSGVQEDSDSSSEEDETVGTSDASVEDPVVEWQSESSSSDS---SSEYSDWTADA-GINLQPPKRQTRQTTRKICSSSDEE----NLKSLEERQKKPKQTRKKKGGL--VSIAGEPNEEWFAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPWNKMDLREQEFVKIVGIKYEVGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPEGTAFPDEVGAGVPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINHLLSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIRRRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIGDQSCTDILDTYNKIKAEE-RNSTDAEEDTEIVDLDSDGPGTSSG----RKVKCRGRRQSLKCNPDAWKKQCKELLSLIYEREDSEPFRQPADLLSYPGHQEQEGESSESVVPERQQDSSLSEDYQDVIDTPVDFSTVKETLEAGNYGSPLEFYKDVRQIFNNSKAYTSNKKSRIYSMMLRLSALFESHIKNIISEYKSAIQ---------------------------------SQK------------------------------------RRRPRYRKRLRSSSSSLSSSGAPSP-KGKQKQMKLQPKNDQNTSVSHARTSSPFSSPVSDAAEG-------------LSLYLLDDEPDGPFSSSSFGGYSRSGNSHDPGKAKSFRNRVLP---VKQDHSLDGPLTNGDGREPRTGIKRKLLSASEEDENMGGEDKEKKETKE---KSHLSTSESGELGSSLSSESTCGSDSDSEST------SRTDQDYVDG-DHDYSKFIQT-------------RPKRK------------------------------------LRKQHGNGKRNWKTRGTGGRGRWGRWGR----------------------------------------------------------------------------WSRGGRG----------------------------------------------------------------------RGGRGRGSRG----RGGGGTRGRGRGRGGRGASRGATRAKRARIADDEFD----TMFSG------RFSRLPRIKTRNQGR-----------RTVLYNDDSDNDNFVSTEDPLNLG-TSRSGRVRKMTEKARVS----HLMGWNY---------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PQW9-1", "uniprot_id": "A0A8M9PQW9_DANRE", "id": "A0A8M9PQW9-1", "name": "", "aln": "---MAAEPCSQIEAELYYLIARFLQSGPCQKSAQMLLQELHEYEIIPKRWSCDGEQFKRSFDDWVLLNQHIPADYLLRVCKQVGPLIDKHIPPSVPGVHSLLGTGRQSLLRTAKSSSHTLWSGSAVAALHRGRPPEPPISCAKSPNIVSIIGARQKTGVARFGHAFPSCAYQHMKMHRRILGHLSSVYCVAFDRTGRRIFTGSDDCLVKIWATDNGRLLATLRGHAAEISDMTVNFENTLLASASCDKIVRVWCLRTCAPVAVLQGHTASITSIQFSPSALGSSRFLATTGADGMVCFWQWNSFS---MKFVDKPVKFMERSRPG-VQISCSSFSSGGLFLATGGTDHMIRVYYLGTEMPVKFSDLDSHTDKVVAIQFCNNTDSLRFVSGSRDGTARIWHYQQQEWKSTVLDMTTRLPGSAVISGDDKSTKLVVTMVAWDRCDRSIITAVSNCLLKVWNSTNGQLLHVLLGHDDEVFVLEAHPFDSRILLSAGHDGNIYVWDLSKGQKIRNFFNMIEGQGHGAVFDCKFSVDGQHFACTDSHGHLLIFGFG-CSQPYEMIPDQMFFHTDFRPLIRDSNNFVLDEQTQQAPHLMPPPFLVDVDGNPHPPRCQRLVPGRENCKEEQLVPQL-----GYMANGDGEVVEQVIGQQTADES--------------QEESPLDDLIRQLQNQQ-------DERVNQAN-------PAGAEVAGGPLSP-------PNVGLRR-SGQVEGVRQMHNNAPRS----------QMATERDL-LAWSRRVVVNEVQAGIFRVMEDCRLAKGEVERSYYIIEKKRKSVPSTGSQPGDNVR--TLRRPQ--------RKAQQKR-HAYQTRSTRTRRRSGSVQSFSRNEETEVESESEAEQEEDQNENSDGTSEGETQWENDSSSSDS---SSEYSDWTADA-GINLQPPKRTTRRPARVAVSSSSEDEEGTGQGEGEAAQTTKQAEKKKKPKQ--RSVPAGELEEWLPPSWIMETIPRRSPFVPQMGDELIYFRQGHQAYVRAVSRAKAYSINPQKQPWNRLNLRDQESVKVVGIKYEVGPPTLCCLKLAILDLTSGKMTNESFSLKYHDMPDVIDFLVLQQFYNEAKERNWQPGQRFRSIIDDAWWFGSLECQEPFESEYPDSLFQCYIVRWDNGEREKMSPWDIEPIPEEAPLPEEDGDSVPVTEDELQALLYSPQEGEWGLHTRDEECERVITAIDQLLTLDVAKAFSNPVNLREYPLYCTVVAYLTDLSTIRTRLVHRFYRRISALMWEVRYIEHNARTFNEPQSPIVTAAKTVSDVLLRFIRDQNCTDILDLYNKMKSEF-SSE---EDEEETVDVDSDTPGTSTGQ---RRSNSTPQKRGVVLDINAWHKQCKDLVRRMIVSSDSEPFRQPVDLFTYP-------------------------DYRDIIDTPMDLGTVSETLTGGNYENPIEFAKDVRLIFSNSKAYTPNKKSRIYSMTLSLSAFFENQIIPIISDYKSAVQ---------------------------------NQR------------------------------------RSQ----QRLMCSKR-LQSSSPNSP-KGKQKSGK---KTLQMSAKARTRKSSQDSN-VAQVDE--------------------DSQPSSSSSSSSSSSSSSSFSSEQAGANRVTRSQVTS---SKS----SGVFLPNGGRSSRR--RRAVLTE----------EGEVSECES---TSSSSSSTS----ASSSSSATSSSSSESDDS------SAEVSGFADGGDHDYSKAPQH-------------KQKGK------------------------------------APAPPPPPSPPPPAPTIDNPKRKRKGEE----------------------------------------------------------------------------EQSAEPE----------------------------------------------------------------------KRPRRTSSRE----EEEEEEEEEVDDEPEEEEEPDEEEEPEEEEEESDDE----NVISPSKRSNQRTPKSGRVNTRNQGR-----------RTVLYNDDSEEE--GPTSDPLNLG-MSRSGRVRRMTERARVS----HLMGWTH---------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VC96-1", "uniprot_id": "Q9VC96_DROME", "id": "Q9VC96-1", "name": "", "aln": "METRQPSSGDDLKPELYFLISKFLAAGPLEETAKVLIRELEEKKVLPRRLDWQGNEHEQTFEELERKYKHIGANHLLEICSRLGPLVDRELPPSVPGINSLLGTGRQNLLRTKETVYCHRSLRDYCTRLNGVSLPDS-VLTKPTHNLDRVLTGREHGGEVRRKLLVPTDLYRRTKLLRRTVGHLSSVYCVLFDRTGRYIITGADDLLIKIWSAADGRLLATLRGASSEITDIAINLDNTMLAAGSLDHILRVWDMQTTSPIAVLSAHTGMITSVNFCPSPRSDLKYLVTTSTDGSIAFWQYSTPRGQKITFAPKPTQYHEKLRPGQAQMMCTTFSPGGIFLAAGSADHHVRVYMMGEDGPKRILETEAYTDAVDSVQWSHRG--LRFISGSKDGTAHIWTFESQQWKSSKLCMTERLASCPEP---EEGKRLKVTMVAWDASDRYVITAVNDFTIKIWDSKSAKLHRVLRGHKDELYVLESNPRDEHVLLSAGHDGQVFLWDIEQGVCVANFLNDIDGQGHGSVFDAKWSPDGTMIAATDSHGHILIFGLGVCIEKYKMLPTELFFHTDFRPLLRDAQHHVVDEQTQIMPHLMPPPFLVDADGNPHPSRFQRFVPGRESCSLDQLIPNLTVGVDGVVIDDGGAGGDAVVAAAPAEAPPAALPPAAAGGPQGANYSHIDRMIAALANRQSVNVNANDANPTNGNQSFERLTNRQMPDSNGRQSSRGNVLGSRLSTPRQGWGAAAAAPVEDQAGPSQPPAEPAAEPGQAQVQQALPLKFIRRTYVRPMKYPQLQNLKQTIYSAGQFEKQEYKREMRRRPIMINTASAASSQQPGSVGRPRNTRGNGGGARAGRRRGPQPAGGQPQPAYRTRAVRDQEPEHYDEVAPPPEEEEEDVSSNSSGDTSYSNVEENLEDSSDESETDSSDYSDWVADTPGPNLEPPKRSKRKPLSRRPRSSDDSSDDERAGRSRGGQVTARKVGRKTVLFPPTDANGEIPELYRPAEWLSEVIPRKAPYYPQMGDEVVYFRQGHAKYLDAVRLKKVYKLSHSSEPWNFHTLRDHELVRVIGIKYEIRPPRLCCLKLAIID-EEGNMTGTTFKIKYHDMPDVLDFLVLRQTFDLAVQRNWSIGDRFRCMIVDGWWMGQIESRHALSADFPDSSFMCFRVRWDNGEYEFMSPWDMEPIDQ-QRVPDEVGGAVPVLPEEIRATLYQPKSEEWHRGDRDGTCRRIINGLEQVMRLSIAEHFLAPVDLNIYPDYAYLIEYPIDLTTIKSRFENHFYRRITSAQFDVRYLATNAEQYNRRHAIIVKHSRIVTDLCLRIIREPDEIDVAAVYHQLADVYHSSESENEVDSDVVPSTSTGPTTSAAAAAARQRVSSARRSTRIHSEGDWRADCRQLLDLMWARTDSAPFREPVDTIDFP-------------------------DYLEIIATPMDLRTVKEDLLGGNYDDPLDFAKDVRLIFQNSKNYNTNKRSRIYAMTLRLSALFESHIKTVVTSWKAALRRANKNKSGSSGGGRGGSSSSPNKRVKKERSTRRNQKPTAAARRLPVANSSEDEDEEDDDDDDDDDDEEEASTRGRSRRRNGVAVSASSSGSNRVTSSSAAQQRRGKSSSSEEEEEEETSAQATSDASSDEEERAQSNDSSPQQTRTRRARQRQRLSDDSNINDSEDSYNPNEGRGSRRRPGAARPSSNRQTNGHSSKRRRLNKSPANAAPGPSLPRRTRRIAGSSAEEAASHSQHDESTQDSQIGRRKGRSASSRSIGNGPSTSAAAAANSSLESPSRNTRANGTRTSSHLGAENDHSYHLPVRNGRIIESDTDSPVIRPTRQSAKRALMDWGRGSDIEEEEEEEEEDSEEAEEILPTPTKDDLPSTSRAALAQAAAGPSRQLRTNRNTVVRPAQSDDDDDDDSDNEPLANNQQKNYQSPAKSSSTATVAPHPLSLRRRLASPPERNTHMTRSHATSTTSSAAASRAEQQPAVSTHDHNYLGNVNSSRAPRRILSRHQRNADELDTSLDVLENSRLLSAIANHRRPTSTTNSNSASNVVTRRLRGRASQANSHDEDHEEEEAAASDEGTDGGSSSQSYEDEDEDSDSEDNQPLTSYVSPSNGRPRRKAKTSSSSATTQERPLRRTRRPPSNNSIANDNDDDDDYVVPRSRRANRGGNQRAGRNQKRPRYNEQSEEEEAAAGYSHRSKRIRNGDAHASSQERSQASTERDQEEEEDGTSVDSEEQQVNVSSRGRVRKPSAKARGIFKE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :::.***:**::** :** :::*::*::**.* :::*:* . :*::..::*:: ** .::**.:*.::***:*:.:* ****:::***.***.*** : . : *: *: : . *: : .*: * * .*: *:: *: :* :********* ***:** *:**:** *:***:: :********* ::**:*:::* :**::*:.* *:::*** ::* :*:***..*:. ***::*.**. . ::*.:*.:** :.***: :.* :*.:: *: *** .*: *::**.**:*:::*.:** :*:* :* : * :: : :::** * ::*:.:. ***:***:****:** ::.*:*** * *: ::.. :: .:* ******* * :****.: :*:*:* ..:* :.* **.**::***::* *.:::*******::::**:.:* : *::* *:*****:***.*:* ** :*.******:*:**:* * : *: :* ::*****:***:**:::.*:***** ***********.******.: **:*****.*. :**:*:* * : :..* : *:. . : : * :* :* * ..* * . : . .. *. *: . .. .: .* . * .:: * : : **. *. :: : :: : *:.* . * * ::: . . : *. :: ::* . : : : . .. *::: . .. ... .: : :.**.:* **:**** **: * **:**** .*:. **.:. . * . : :*. . . * : ...*: :.***::*: ******::****** *: ** * *.:. ..:*** **::* *:::*****: ** *******::* .*:**. :*.:********:*****:* :: * :***. *:***.:* *.**:* :*.:..:..::*** * *: *:***.* * *****:*** : .*:* * .:** :*: * **.*:. ** ** *.*:* .::::: *..*. * **:* ** *. :: * **.**: *: ::*****:: ::***: **. :*. .: **. :: *:*: **:* : . *: *::: .. * : : * * * **:. *: . :: . . *: :*.:*: : ** ***:*.* .* ** : : **:*: **.* * .*** .*::* **** **.*** *..**:****:* * ***:**.:* :::.:*:*:: .*: * : : : * *. *. .:*: * . : :: :* *. : : ..: . * .* . . . . .* : .: * .. * . :* : : . .: : ::* * .* *: ::..*. :* . : . **.* : : . : . : . * : . . . : * ..: . . .. . . . . :.: : . .: * .: .: .* * .:: ::*.::: . . * * .*:** :: .. . * *:.: ", "identical_positions": 557, "similar_positions": 581, "identity": "24.59%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-47", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06727-1", "uniprot_id": "APOA4_HUMAN", "id": "P06727-1", "name": "Apolipoprotein A-IV", "aln": "MFLKAVVLTLALVAVAGARAEVSADQVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEVNTYAGDLQKKLVPFATELHERLAKDSEKLKEEIGKELEELRARLLPHANEVSQKIGDNLRELQQRLEPYADQLRTQVSTQAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKVNSFFSTFKEKESQDKTLSLPELEQQQEQQQEQQQEQVQMLAPLES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06728-1", "uniprot_id": "APOA4_MOUSE", "id": "P06728-1", "name": "Apolipoprotein A-IV", "aln": "MFLKAAVLTLALVAITGTRAEVTSDQVANVVWDYFTQLSNNAKEAVEQFQKTDVTQQLSTLFQDKLGDASTYADGVHNKLVPFVVQLSGHLAQETERVKEEIKKELEDLRDRMMPHANKVTQTFGENMQKLQEHLKPYAVDLQDQINTQTQEMKLQLTPYIQRMQTTIKENVDNLHTSMMPLATNLKDKFNRNMEELKGHLTPRANELKATIDQNLEDLRRSLAPLTVGVQEKLNHQMEGLAFQMKKNAEELQTKVSAKIDQLQKNLAPLVEDVQSKVKGNTEGLQKSLEDLNRQLEQQVEEFRRTVEPMGEMFNKALVQQLEQFRQQLGPNSGEVESHLSFLEKSLREKVNSFMSTLEKKGSPDQPQALPLPEQAQEQAQEQAQEQVQ-PKPLES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58HH61-1", "uniprot_id": "A0AC58HH61_DANRE", "id": "A0AC58HH61-1", "name": "", "aln": "-MMWISDSTALPTGLWVSTTAVTSPCYINIDWNYSPSHLFLNRTASIKAKQHRLAASVN----------------IMKVLVVFALAVFTGCQAN-LFYADEPKPQLEQLTDAFWSYVSKATQTAEETVKMIRE------SQLGQEVNERLTQSADMASEYAVVLKKQVDPLTEELMNKITKETEVLRERLGQDLINVREKLEPYADNMKSQIQQRVEELRAAMAPYADSLDS------ETLKATLLQKSEELRGNLEQSVKELQVQLEPYTAELK------------------EKVDQHLQEFQKTVTPLTEDLQVQIRERAQMVQQSLTPYAEDLKEKLDPYAQNLKDQLASLYESYTKRN----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * ..: : : *:: .: *:* .. : * : :: :: .:. : : ** *. : : :* :**:* : .:..:.:*. :.:: ::: :* ::. : : : * :: : .:.* .: : *: ::.::: ::: :* * *:::* *:* :*:** ::** : . :. * * : :::***: .:. . .:*: .* * . ::: :::*:::**:: * * * :: : :: : .:*.* * : ::: :*. :.*:::: *: .: :: ", "identical_positions": 48, "similar_positions": 137, "identity": "12.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-51", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P62955-1", "uniprot_id": "CCG7_HUMAN", "id": "P62955-1", "name": "Voltage-dependent calcium channel gamma-7 subunit", "aln": "--MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWRVCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAASSFLLKEGAGVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQPEAWR---RGRSPSDISSDVSIQMTQN----------------------------------------YP----------------------------PAIKYPDHLHISTSPC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P62956-1", "uniprot_id": "CCG7_MOUSE", "id": "P62956-1", "name": "Voltage-dependent calcium channel gamma-7 subunit", "aln": "--MSHCSSRALTLLSSVFGACGLLLVGIAVSTDYWLYMEEGTVLPQNQTTEVKMALHAGLWRVCFFAGREKGRCVASEYFLEPEINLVTENTENILKTVRTATPFPMVSLFLVFTAFVISNIGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPSSSEQYFHYRYGWSFAFAASSFLLKEGAGVMSVYLFTKRYAEEEMYRPHPAFYRPRLSDCSDYSGQFLQPEAWR---RGRSPSDISSDVSIQMTQN----------------------------------------YP----------------------------PAIKYPDHLHISTSPC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58HJA9-1", "uniprot_id": "A0AC58HJA9_DANRE", "id": "A0AC58HJA9-1", "name": "Voltage-dependent calcium channel gamma-7 subunit", "aln": "MRMSSCSSRALTLLSTVFGACGLLLVGVAVATDYWLLMEEGIVLQQNQTVDVKMALHSGLWRVCFIAGTEKGRCVASEYFTEPEIEITTENTANILKMVRTATPFPMVSLLFVFTAFIISNVGHIRPQRTILAFVSGIFFILSGLSLVVGLVLYISSINDEVMNRPREPEQFFNYRYGWSFAFAASSFLLKEGAGVMSVYLFMKRYAEEEMYRPHPTLYRPRLSEGSDYSGQYLHPETWPPPQRARSASEISSDISIQLTQNPQHPSKASGQQGTSSPGITAASSPASGTGYQLPSPGSAAPYPHNHPLHPGAHGPAAASQAMPMSAPPAAVPPPHYHTHMRMSASPC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** **********:***********:**:***** **** ** ****.:******:*******:** *********** ****::.**** **** ************::*****:***:******************************************** ..**:*:**************************** *************::******: ******:*:**:* *.**.*:****:***:*** ** *. :* *:::*:***", "identical_positions": 225, "similar_positions": 35, "identity": "64.66%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-55", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99418-1", "uniprot_id": "CYH2_HUMAN", "id": "Q99418-1", "name": "Cytohesin-2", "aln": "----------------MEDGVYEPPDLTPEERMELENIRRRKQELLVEIQRLREELSEAMSEVEGLEAN-EGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVENELLQNTPEEIARFLYKGEGLNKTAIGDYLGEREELNLAVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEELLRNLYDSIRNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAVSVDPFYEMLAARKKRISVKKKQEQP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63034-1", "uniprot_id": "CYH2_MOUSE", "id": "P63034-1", "name": "Cytohesin-2", "aln": "----------------MEDGVYEPPDLTPEERMELENIRRRKQELLVEIQRLREELSEAMSEVEGLEAN-EGSKTLQRNRKMAMGRKKFNMDPKKGIQFLVEHELLQNTPEEIARFLYKGEGLNKTAIGDYLGEREELNLSVLHAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCLCNPGVFQSTDTCYVLSFAVIMLNTSLHNPNVRDKPGLERFVAMNRGINEGGDLPEDLLRNLYDSIRNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVDDPRKPNCFELYIPNNKGQLIKACKTEADGRVVEGNHMVYRISAPTQEEKDEWIKSIQAAVSVDPFYEMLAARKKRISVKKKQEQP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F1N2-1", "uniprot_id": "E7F1N2_DANRE", "id": "E7F1N2-1", "name": "Cytohesin-2", "aln": "MTFDSETYMPKSKAPKMDDLDYIPADLSPEERSELEEIRRRKGALLLEIQRLKEELREAIIEVEGLETSTEGSKTLQKSRHVAMGRKKFNMDPKKGIVFLVENELLRHTPEDIAQFLYKGEGLNKTAIGDYLGERDDFNIKVLQAFVDLHEFTDLNLVQALRQFLWSFRLPGEAQKIDRMMEAFAQRYCHCNPGVFQSTDTCYVLSFAIIMLNTSLHNPNVRDKPTVERFISMNRGINDGGDLPEELLRNLYDSIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGG-RVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYIPNNRGQLIKACKTEADGRVVEGNHMVYRISAPTPEEKDEWIHSIKSAVSVDPFYEMLAARKKRISLKKKEEQP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:* * *.**:**** ***:***** **:*****:*** **: ******:. *******:.*::*************** ****:***::***:**:********************:::*: **:********************************************* ******************:**************** :***::******:******:*********:******************************** ******************************************:***************:***************************** *******:**::*******************:***:***", "identical_positions": 349, "similar_positions": 37, "identity": "83.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-56", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70605-1", "uniprot_id": "KCNN3_RAT", "id": "P70605-1", "name": "Small conductance calcium-activated potassium channel protein 3", "aln": "--MDTSGHFHDSGVG-DLDEDPKCP---CPSSGDEQQQQQQP--------PPPSAPPAVPQQPPG---------------------PLLQPQPPQLQQQQQQQQQQQQ-----------------------------------------QQQQQQQAPLHPLPQLAQLQSQLVHPGLLHSSPTAFRAPNSANSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVMKPLSRLSASRRNLIEAEP------EG-----------QPLQLFSPSNPPEIIISSRED---------------------------NHAHQTLLHHPN-----------------ATHNHQHAG---------------------------------------------------------------TTAG-STTFPKANKRKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELS-WGLYSKDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWTARLAFS-YTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRGVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLIADTLRQQQQQLLTAFVE--ARGISVAVGTSHAP------PSDSPIG---ISSTSFP--TPYTSSSSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P58391-1", "uniprot_id": "KCNN3_MOUSE", "id": "P58391-1", "name": "Small conductance calcium-activated potassium channel protein 3", "aln": "--MDTSGHFHDSGVG-DLDEDPKCP---CPSSGDEQQQQQQP--------PPPPAPPAVPQQPPG---------------------PLLQPQPPQPQQQQSQQQQQQQ-----------------------------------------SQQQQQQAPLHPLPQLAQLQSQLVHPGLLHSSPTAFRAPTSANSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVMKPLSRLSASRRNLIEAEP------EG-----------QPLQLFSPSNPPEIIISSRED---------------------------NHAHQTLLHHPN-----------------ATHNHQHAG---------------------------------------------------------------TTAG-STTFPKANKRKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELS-WGLYSKDSMFSLALKCLISLSTVILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWTARLAFS-YTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRGVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLIADTLRQQQQQLLTAFVE--ARGISVAVGTSHAP------PSDSPIG---ISSTSFP--TPYTSSSSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGI6-1", "uniprot_id": "KCNN3_HUMAN", "id": "Q9UGI6-1", "name": "Small conductance calcium-activated potassium channel protein 3", "aln": "--MDTSGHFHDSGVG-DLDEDPKCP---CPSSGDEQQQQQQQQQQQ---QPPPPAPPAAPQQPLG---------------------PSLQPQPPQLQQQQQQQQQQQQ-----------------------------------------QQ------PPHPLSQLAQLQSQPVHPGLLHSSPTAFRAPPSSNSTAILHPSSRQGSQLNLNDHLLGHSPSSTATSGPGGGSRHRQASPLVHRRDSNPFTEIAMSSCKYSGGVMKPLSRLSASRRNLIEAET------EG-----------QPLQLFSPSNPPEIVISSRED---------------------------NHAHQTLLHHPN-----------------ATHNHQHAG---------------------------------------------------------------TTAS-STTFPKANKRKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELS-WGLYSKDSMFSLALKCLISLSTIILLGLIIAYHTREVQLFVIDNGADDWRIAMTYERILYISLEMLVCAIHPIPGEYKFFWTARLAFS-YTPSRAEADVDIILSIPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKINFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDQQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLLKKIDHAKVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLIADTLRQQQQQLLSAIIE--ARGVSVAVGTTHTP------ISDSPIG---VSSTSFP--TPYTSSSSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FAT2-1", "uniprot_id": "E7FAT2_DANRE", "id": "E7FAT2-1", "name": "", "aln": "--MDPPPSLNLALLSGSEDEEQRLP---LPLGGISHASLSGN-------YPGTNHSNHTGGNSSL---------------------ERLNGTPSPTTPNLPPAS----------------------------------------------------LPKLPLSTTPQLSTP--IPNALHPTSTPLSSCLGS-----QHSLSGETSPVYNALFYSSHSPSTERERERERGCKHRQASPLVHRRDSNPFTEIAMSSCKYSGGVMKPLSRLSASRRNLIESDSGSDTK-EGGASTSQVTAASSQHSQPQPQNPPEIVISSKEDPP-----------------YGHAYELEASANQMSIYHQNHALSESRSVLGGAAG--GGTNGRRGG---------------------------------------------------------------AAGGPGRTASKAPKRKNQNIGYKLGHRRALFEKRKRLSDYALIFGMFGIVVMVIETELS-WGVYSKSSMYSLALKCLISLSTIILLGLIIAYHAREVQLFVIDNGADDWRIAMTMERVLLIALELIVSAVHPVPGDFKFMWRARLAFS-YAPSQAEADLDMVLSVPMFLRLYLIARVMLLHSKLFTDASSRSIGALNKVHFNTRFVMKTLMTICPGTVLLVFSISLWIIAAWTVRVCERYHDAQDVTSNFLGAMWLISITFLSIGYGDMVPHTYCGKGVCLLTGIMGAGCTALVVAVVARKLELTKAEKHVHNFMMDTQLTKRIKNAAANVLRETWLIYKHTKLMKKIDHSRVRKHQRKFLQAIHQLRSVKMEQRKLSDQANTLVDLSKMQSVMYELMSELNDRSEDLERQMLSLEQRVERLTAGFNALPAHLSATLSSQHAALVQLLRERDAKVLSPTVPSALSPTAASLPLANPPSGSGSIPSTQPAEDSPNTSSSSC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KVW5-1", "uniprot_id": "KCNN_DROME", "id": "Q7KVW5-1", "name": "Small conductance calcium-activated potassium channel protein", "aln": "MSIQKLNDTTNSGYVSSEETDSLLVSSSNPSKGGGRTALLRQVKSNSTNGPTTGASTSSSGSVSGGGGGSGSGGGSASGSAAGASKPTLMRQDRTSTYLTSPQQSQHARMGSEESMRGGASGAAGHDEDVEQGLVRSSIVPDIEVHEEDQEQHSQQLNATTMATMTNNQQQQQPTISIMNLSLKPGDSHSHSSSPGSHPNLGTSSYQNLASSIPPSVPSRCRACRNCSRRASTTPTTLIDRSASRDSVKSAFQQGNLSGSMAICISNSALPQQQQLQQQYHLQQQQQQHYQLQQHHLHQQQLQQSQQQVPPVLITSSPTNGSRIIRQSSQPESSSTAICCGPHSACVGHAHSHSHTVPNVSLKQLRESSGDGIAGIAADSLRINGGMRPFKQLRKPASTLSIPGSMKTPSIANREQISSGCNEEAAEALVGIHSDYPRYEMYMEERALTGGNTSRKPSTNSAKHKPNVGYRLGKRKALFEKRKRISDYALVMGMFGIIVMVIENELSSAGVYTKASFYSTALKTLISVSTVILLGLIVAYHALEVQLFMIDNCADDWRIAMTWQRISQIGLELFICAIHPIPGEYYFQWTTKLANKNKTIGTEMVPYDVALSLPMFLRLYLICRVMLLHSKLFTDASSRSIGALNRINFNTRFVLKTLMTICPGTVLLVFMVSLWIIASWTLRQCERFHD--EEHANLLNSMWLTAITFLCVGYGDIVPNTYCGRGITLTCGMVGAGCTALLVAVVSRKLELTRAEKHVHNFMMDTQLTKRLKNAAANVLRETWLIYKHTRLVKRVNPGRVRTHQRKFLLAIYALRKVKMDQRKLMDNANTITDMAKTQNTVYEIISDMSSRQDAIEERLTNLEDKMQSIQEHMESLPDLLSRCLTQHQERIEQRRNF--LHPDTAAVAPIQAP---------TPQS----MFNAAPMLFPHSS----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : . : : * * : * . . . * . .:. .: . . : . . *. * ** .:.*:.* *. .: *:.. : **.: :*. : .::: :: : : . . . . ** :: ** : *:. * . . : * : .. . . .. ::: *:**:**:*:********:*****::*****:*****.*** *:*:* *::* *** ***:**:******:***: *****:*** ********* :*: *.**:::.*:**:**:: * * ::** . : . . *: **:*********.**********************:::******:*************** :******:**:* ***:** : :*:*.:*** :****.:****:**:****:*: * *::*******:****:******:*****************:******************:*:*::: .:**.****** **: ** ***:**** *:***:.*::* *..:*::::::..*.: :*.:: .**.::: : :::** :: * .:: : : : :* . :* .* . . . * :* ", "identical_positions": 290, "similar_positions": 190, "identity": "30.59%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-57", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24473-1", "uniprot_id": "GSTK1_RAT", "id": "P24473-1", "name": "Glutathione S-transferase kappa 1", "aln": "MGPAPRVLELFYDVLSPYSWLGFEVLCRYQHLWNIKLKLRPALLAGIMKDSGNQPPAMVPHKGQYILKEIPLLKQLFQVPMSVPKDFFGEHVKKGTVNAMRFLTAVSMEQPE---MLEKVSRELWMRIWSRDEDITESQNILSAAEKAGMATAQAQHLLNKISTELVKSKLRETTGAACKYGAFGLPTTVAHVDGKTYMLFGSDRMELLAYLLGEKWMGPVPPTLNARL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCM2-1", "uniprot_id": "GSTK1_MOUSE", "id": "Q9DCM2-1", "name": "Glutathione S-transferase kappa 1", "aln": "MGPAPRILELFYDVLSPYSWLGFEVLCRYQHLWNIKLQLRPTLIAGIMKDSGNQPPAMVPRKGQYIFKEIPLLKQFFQVPLNIPKDFFGETVKKGSINAMRFLTTVSMEQPE---MLEKVSREIWMRVWSRDEDITEYQSILAAAVKAGMSTAQAQHFLEKISTQQVKNKLIENTDAACKYGAFGLPTTVAHVDGKTYMLFGSDRLELLAYLLGEKWMGPVPPTANARL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2Q3-1", "uniprot_id": "GSTK1_HUMAN", "id": "Q9Y2Q3-1", "name": "Glutathione S-transferase kappa 1", "aln": "MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLPRKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPE---MLEKASRELWMRVWSRNEDITEPQSILAAAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGAFGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PDP8-1", "uniprot_id": "A0A8M9PDP8_DANRE", "id": "A0A8M9PDP8-1", "name": "Glutathione S-transferase kappa", "aln": "MISSGKVIKLFYDISSPYSWLAFEVLCRYKNIWNVELKLKPAYLAGVMYGSGNQPPVLNPSKLLYMTSDLTLLSQYFGVPMYRP----SKLIKKDSVIPMRFVTAVAEKEKDGDDLVEKVSRELWKRMWSTHQDIVQPASLTEVGIKAGFSANEVDDILILAKSQQIKDRLTSITNEALKYKCFGLPFIVVQVDGKAGVFFGSDRFELMAYFLGEKWFGPHPT------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : ::****: ******.**:****:::**::*:*:*: ::*:* .***:** : * * *: .:: ** : : :*: * . ::*.:: .***:*:* :. : ::**.***:* *:** .:**.: .: .. ***::: :.: :* : :*.:* . * * :* .**** *.:***:: ::*****:**:*::*****:** *. ", "identical_positions": 86, "similar_positions": 80, "identity": "37.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-58", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K0E7-1", "uniprot_id": "SERC2_MOUSE", "id": "Q8K0E7-1", "name": "Serine incorporator 2", "aln": "--------------------------------------------------------------------------------------------------------------MGACLGACSLLS---CASCLCGSAPCILCGCCPSTRNSTV-SRLLFTSFLFLGVLVSIIMLSPGVESQLYKLPWVCEDRTQQP-----LVLQG--PLDCGSLLGFRAVYRMCFATAAFFFFFMLLMICVRSSRDPRAAIQNGFWFFKFLILVGITVGAFYIPDGSFPKIWFYFGVVGSFLFILIQLILFVDFAHSWNQRWLCKAEECDSPAWYAG--LFFFTFLFYLLSIAAVALMFVYYTESGACHEGKVFISLNLTFCVCVSIIAVLPKVQDAQPNSGLLQASVITLYTMFVTWSALSNVPD-QKCNPHLP------------TKNG--TGQVDLEDYST-VWWDAPSIVGLVIFILCTFFISLRSSDH---RQVNSLMQTEECP---AEMVQQQQVAVSDGR-AYDNEQD----GVTYSYSFFHFCLVLASLHVMMTLTNWYS-----PGE-TRKMIS--TWTSVWVKICASWAGLFLYLWTLVAPLLLPNRDFS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4FZV1-1", "uniprot_id": "Q4FZV1_RAT", "id": "Q4FZV1-1", "name": "", "aln": "MALVKFKSRFISKSLLWFSIQSELRVGLGCAPVVAGLFPISASLGKVWRQHLSQVSPTRSRALPESDERLRQVGRGRGGDGLGVGPVKAPRVPPDPGSEAGAPRPAPRTAMGACLGACSLLS---CASCLCGSAPCILCSCCPSTRNSTV-SRLLFTGFLFLGVLVSIIMLSPGVESQLYKLPWVCEDRAQQP-----VVLQG--PLDCGSLLGFRAVYRMCFATAAFFFLFMMLMICVRSSRDPRAAIQNGFWFFKFLILVGITVGAFYIPDGSFPKIWFYFGVVGSFLFILIQLILFIDFAHSWNQRWLCKAEECDSPVWYAG--LFFFTFLFYLLSIAAVALMFVYYTESGACHEGKVFIGLNLTFCVCVSIIAVLPKVQSAQPNSGLLQASVVTLYTMFVTWSALSNVPD-QKCNPHLP------------TKNG--TGQVNLEDYST-VWWDAPSIVGLVIFILCTFFISLRSSDH---RQVNSLMQTEECP---AEMVQQQQVAVGDGR-TYDNEQD----GVTYSYSFFHFCLVLASLHVMMTLTNWYS-----PGE-TRKMIS--TWTSVWVKICASWAGLFLYLWTLVAPLLLPNRDFS----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96SA4-1", "uniprot_id": "SERC2_HUMAN", "id": "Q96SA4-1", "name": "Serine incorporator 2", "aln": "--------------------------------------------------------------------------------------------------------------MGACLGACSLLS---CASCLCGSAPCILCSCCPASRNSTV-SRLIFTFFLFLGVLVSIIMLSPGVESQLYKLPWVCEEGAGIP-----TVLQG--HIDCGSLLGYRAVYRMCFATAAFFFFFTLLMLCVSSSRDPRAAIQNGFWFFKFLILVGLTVGAFYIPDGSFTNIWFYFGVVGSFLFILIQLVLLIDFAHSWNQRWLGKAEECDSRAWYAG--LFFFTLLFYLLSIAAVALMFMYYTEPSGCHEGKVFISLNLTFCVCVSIAAVLPKVQDAQPNSGLLQASVITLYTMFVTWSALSSIPE-QKCNPHLP------------TQLGNETVVAGPEGYET-QWWDAPSIVGLIIFLLCTLFISLRSSDH---RQVNSLMQTEECPPMLDATQQQQQVAACEGR-AFDNEQD----GVTYSYSFFHFCLVLASLHVMMTLTNWYK-----PGE-TRKMIS--TWTAVWVKICASWAGLLLYLWTLVAPLLLRNRDFS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AIB7-1", "uniprot_id": "A0A8M3AIB7_DANRE", "id": "A0A8M3AIB7-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MGACMALCSLAS---CASCLCGSAPCLLCGCCPSTNNSTI-TRLIFSFFLLLGTLVSVIMILPGMETQLRKIPGFCQGGTTIP-----GIEN---HVNCDVIVGYKSVYRMCFAMACFFFLFFAIMIRVKSSKDPRAAVQNGFWFFKFLILVGITVGAFFIPDGTFHDVWFYFGIVGSFAFILIQLILLIDFAHSWNEVWVRNAEEGNSKCWFSG--LLFFTILYYALAFAAIVLFYLYYTKPDNCTEHKFFISFNLILCVIVSVVSILPKVQDASPQSGLLQSSIITLYTMYVTWSAMTNNPN-RECNPSLLG---------LVSNISTTEAVPTSSPGTV-QWWDAQGIVGLVIFLFCTFYASIRSSSN---AQVNRLMQTEEGK---GGVGGEEVGEDGLRR-VVDNEED----GVTYNYSFFHFHLLLASLYIMMTLTNWYK-----PDTTTQAMQS--TMPAVWVKICSSWLGLGLYLWTLVAPVIFSNRDFS----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PFR2-1", "uniprot_id": "M9PFR2_DROME", "id": "M9PFR2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MGAALGICSAAQ---CAMCCGGTAASMCCSACPSCTNASS-SRFMYAFILLVGTVLGAIALSPGLQDTLKKMPFCINSTSSYSSGALSAVSGGSLQVDCEYALGYMAVYRVCFGMACFFALMSLIMLGVKSSRDPRSHIQNNFWPLKFLICFGAAIGAIFIPDGSFGPAMMWVGLIGGLAFILVQLVIIVDFAHSLAENWIESAE--NSRGYYYA--LAGVTLLCYILSLTGITLLYIYFTTSTGCGINKFFISINLIFCLAISVISILPAVQERLPHSGLLQSSLVTLYTVYLTWSAVANNPE-KECNPGMFG---------MMEGFGNATTTAAPPTHTTRVTFDTTNIIGLVVWLLCILYNCISSAVE---VSKISHDNSEKRE----ALSDTEAGTDGSGKPSTDTETE----GVTYSWSMFHLVFVCASLYVMMTLTNWYNNFLFPQTSFGNRAVQ--RQRGFHVGQDRLQLAGCLHLWLEPCSAHCSYQSRL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12116-1", "uniprot_id": "TMS1_YEAST", "id": "Q12116-1", "name": "Membrane protein TMS1", "aln": "--------------------------------------------------------------------------------------------------------------MGAVISLPVSMAGSFVASCFGGCCSNLVTKTASSLGSSSLGTRLLYAVWLLLNSLISWVSYS-----ANKSILWPGKTCTGTG------------------ECGFFTVHRLNFALGCLHLILALVLTGVKSTNDVRAALQNSWWSLKFILYLCLIVLSFVIPNDFYIFFSKWVSVPSGAIFILVGLILLVDFAHEWAETCISHVESEDEDSSFWQRFLVLGTTSMYTASIIMTVVMYVMFCH-QQCNMNQTAVTVNLILTVITLVLSVNPKIQEANPKSGLAQSSMVSVYCTYLTMSAMSSEPDDKMCNPLVRSSGTRKFSIILGSLFTFIAIAYTTTRAAANSAFQGTNTNGAIYLGNDIEYEGLGGQTRNQLRYEAIKQAVEEGSLPESALYDTAWLGTSSPTGAMDNQNDDERTGTKYNYTLFHVIFFLATQWIAILLTINVT-----QDDVGDFIPVGRTYFYSWVKIVSAWICYALYGWTVVAPAIMPDRFDYENYY", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** :. * * * .. : ..: .:: :*:::: *::. ::. : .: : : *: :*:*: *. ..:. :: :: * *:.* *: :**.:* :**:: . : :: **:. : :..: .. ***: *::::****. : : .* :. : * * * :: .:::: : * : : .** : : : :: * :*. *:*** *:*::::* ::* **::. *: : *** : . :: . * : : : . . *: *.: : *..*.:::**. :. *: : : ** . * *: * .. : ", "identical_positions": 67, "similar_positions": 136, "identity": "10.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-71", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P15304-1", "uniprot_id": "LIPS_RAT", "id": "P15304-1", "name": "Hormone-sensitive lipase", "aln": "MKP-RRPISFT--REITAMEPSSTSVSRPEWRPEAQQTLTDYPGSRELQEFGIPQKQSLPNEATAQQGAEFQQEQGVQQSTLLQKLLTPLAFPVPQQSFPSHKVHSDQQEATSQNGPGAGKVHTTQKELEHRDEHVGTAESGPAEPPPAT-EVEATSIAQAVSGPDKKLPTQTDLVSQERAEQSDPTAQQTPLVQGVKSDQGSLIESGILARLQKLAIQQPSQEWKTFLDCVTESDMEKYLNSSSKSNPPEPSGGTVIPGT-LPSKQKPDCGKMSGYGGKLPHGKKGILQKHKHYWDTASAFSHSMDLRTMTQSLVALAEDNMAFFS--SQG-PGETARRLSNVFAGVREQALGLEPTLGQLLGVAHHFDLDTETPANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRASHNLAELEAYLAALTQLRALAYYAQRLLTINRPGVLFFEGDEGLSADFLQDYVTLHKGCFYGRCLGFQFTPAIRPFLQTLSIGLVSFGEHYKRNETGLS---------VTASSLFTGGRFAIDPELRGAEFERIIQNLDVHFWKAFWNITEIEVLSSLANMASTTVRVSRLLSLPPEAFEMPLTSDPKLTVTISPPLAHTGPGPVLARLISYDLREGQDSKMLNSLAKSE-GPR-LELRPRPQQAPRSRALVVHIHGGGFVAQTSKSHEPYLKNWAQELGVPIISIDYSLAPEAPFPRALEECFFAYCWAVKHCELLGSTGERICLAGDSAGGNLCITVSLRAAAYGVRVPDGIMAAYPVTTLQSSASPSRLLSLMDPLLPLSVLSKCVSAYSGTETEDHFDSDQKALGVMGLVQRDTSLFLRDLRLGASSWLNSFLELSGRKPHKTPLPATETLRPTDSGRLTESMRRSVSEAALAQPEGLLGTDSLKKLTIKDLSFKGNSEPS-DSPEMSQSMETLGP-STPSDVNFFLRSGNSQEEAETRDDISP----MDGIPRVRAAFPDGFHPRRSSQGVLHMPLYSSPIVKNPFMSPLLAPDVMLKTLPPVHLVACALDPMLDDSVMFARRLKDLGQPVTLKVVEDLPHGFLSLAALCRETRQAAELCVQRIR-----------------LILTPPAAPLT-------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54310-1", "uniprot_id": "LIPS_MOUSE", "id": "P54310-1", "name": "Hormone-sensitive lipase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDLRTMTQSLVTLAEDNMAFFS--SQG-PGETARRLSNVFAGVREQALGLEPTLGQLLGVAHHFDLDTETPANGYRSLVHTARCCLAHLLHKSRYVASNRKSIFFRASHNLAELEAYLAALTQLRAMAYYAQRLLTINRPGVLFFEGDEGLTADFLQEYVTLHKGCFYGRCLGFQFTPAIRPFLQTLSIGLVSFGEHYKRNETGLS---------VTASSLFTGGRFAIDPELRGAEFERIIQNLDVHFWKAFWNITEIEVLSSLANMASTTVRVSRLLSLPPEAFEMPLTSDPRLTVTISPPLAHTGPAPVLARLISYDLREGQDSKVLNSLAKSE-GPR-LELRPRPHQAPRSRALVVHIHGGGFVAQTSKSHEPYLKNWAQELGVPIFSIDYSLAPEAPFPRALEECFFAYCWAVKHCDLLGSTGERICLAGDSAGGNLCITVSLRAAAYGVRVPDGIMAAYPVTTLQSSASPSRLLSLMDPLLPLSVLSKCVSAYSGTEAEDHFDSDQKALGVMGLVQRDTSLFLRDLRLGASSWLNSFLELSGRKPQKTTSPTAESVRPT------ESMRRSVSEAALAQPEGLLGTDTLKKLTIKDLS---NSEPS-DSPEMSQSMETLGP-STPSDVNFFLRPGNSQEEAEAKDEVRP----MDGVPRVRAAFPEGFHPRRSSQGVLHMPLYTSPIVKNPFMSPLLAPDSMLKTLPPVHLVACALDPMLDDSVMFARRLRDLGQPVTLKVVEDLPHGFLSLAALCRETRQATEFCVQRIR-----------------LILTPPAAPLN-------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q05469-1", "uniprot_id": "LIPS_HUMAN", "id": "Q05469-1", "name": "Hormone-sensitive lipase", "aln": "MEPGSKSVSRSDWQPEPHQRPITPLEPGPEKTPIAQPESKTLQGSNTQQKPASNQRPLTQQETPAQHDAESQKEPRAQQKSASQEEFLAPQKPAPQQSPYIQRVLLTQQEAASQQGPGLGKESITQQEPALRQRHVAQPGPGPGEPPPAQQEAESTPAAQAKPGAKREPSAPTESTSQETPEQSD---KQTTPVQGAKSKQGSLTELGFLTKLQELSIQRSALEWKALSEWVTDSESESDVGSSSDTDSPATMGGMVAQGVKLGFKGKSGYKVMSGYSGTSPHEKTSARN-HRHYQDTASRLIHNMDLRTMTQSLVTLAEDNIAFFS--SQG-PGETAQRLSGVFAGVREQALGLEPALGRLLGVAHLFDLDPETPANGYRSLVHTARCCLAHLLHKSRYVASNRRSIFFRTSHNLAELEAYLAALTQLRALVYYAQRLLVTNRPGVLFFEGDEGLTADFLREYVTLHKGCFYGRCLGFQFTPAIRPFLQTISIGLVSFGEHYKRNETGLS---------VAASSLFTSGRFAIDPELRGAEFERITQNLDVHFWKAFWNITEMEVLSSLANMASATVRVSRLLSLPPEAFEMPLTADPTLTVTISPPLAHTGPGPVLVRLISYDLREGQDSEELSSLIKSN-GQRSLELWPRPQQAPRSRSLIVHFHGGGFVAQTSRSHEPYLKSWAQELGAPIISIDYSLAPEAPFPRALEECFFAYCWAIKHCALLGSTGERICLAGDSAGGNLCFTVALRAAAYGVRVPDGIMAAYPATMLQPAASPSRLLSLMDPLLPLSVLSKCVSAYAGAKTEDHSNSDQKALGMMGLVRRDTALLLRDFRLGASSWLNSFLELSGRKSQKMSEPIAEP------------MRRSVSEAALAQPQGPLGTDSLKNLTLRDLSLRGNSETSSDTPEMSLSAETLSP-STPSDVNFLLPPEDAGEEAEAKNELSP----MDRGLGVRAAFPEGFHPRRSSQGATQMPLYSSPIVKNPFMSPLLAPDSMLKSLPPVHIVACALDPMLDDSVMLARRLRNLGQPVTLRVVEDLPHGFLTLAALCRETRQAAELCVERIR-----------------LVLTPPAGAGPSGETG------------AAGVDGGCGGRH--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AJ48-1", "uniprot_id": "A0A8M3AJ48_DANRE", "id": "A0A8M3AJ48-1", "name": "Hormone-sensitive lipase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATAKKSGSG----------VLEKAVSR----------------------RRSSKHKEVPIG-------------------------------------DRTYEDSSMSSEEVMDTKAVFTALYDVCEENAAFFSGATKGQSGDAAQRLVDAMTIIQEHARSLEPVISGFAAIYHHFDFDPHVPANGYRSLVKVVRCCLLHIIHKGRYISSNRRSIFFRASHNASEMEAYCSALCQLRALLYLAQRLLHDNSHGNLFFQEESGLSQSFLREYASMHKGCFYGRCVGFQFTPAIRPCLQSIAISLVAFGDNYKKHQSGIVEAGDIAPYGVAASSFLTSGKYAIDPELRGQEYERITQNLDVHFWKTFWNVTETEVLSSLVSLTATTVKVNRALSVPPVAFDLPLAADPTRTVTLCPPAAHLGPGPVQMRLISHELREGQDSEKLLALCRSEGGPITISLGLKTKRSPPSPWLVLHFHGGGFVAQTSKSHEPYLRSWSHDLNAPVLSVDYSLAPEAPFPRALEECFYAYCWAIKNHNLLGWTGERVCLAGDSAGGNLCVTVSMRAAAHGVRMPDGIVAAYPATLLTVYASPSRLLSLMDPLLPLSVLSRCLSAYAG--TDPQVEKQVEKVSTLSMVKRDASLLLRDFKQGASNWIHSLLDRGSADAVRKSVSEASLTSPHVDPPVPHEGSEYSLEKGTLRSQTCQDLGTHTNSTASNVQKNANHLSTTTANHNSIPDITMTPESKPEDVSFYLCKEVDPSMSEIFSSVAIPPPGGEEDPERPCEFPEGFEPLRSEQ-LAEMNVQSSPIVRNPYMSPLLAPDNMLKGLPPVHIVACHLDPMLDDSVMFAKRLQNIGQPVTLCVVDDLPHGFLSLSQLSRETREAANVCMERIKDVFTMKDPPPEMRKHRKLEQTNPKPSATKRDHTRLSEVTALEEEEGLSVTGGASVVEEAGLTGFYTPTNAEAEKILA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** ::: :* :.*:* **** ::* .*::*:** ..:: ::*:* .***.:. : .: * **:*...*********:..**** *::**.**::***:*****:*** :*:*** :** ****: * ***** * * ***: :.**: .**::*.::*********:********** **:::*.**:**::**::::*: *:***::*.*::******** *:*** *********:***:** ******..::::**:*.* **:** **::**::** ***:.** ** **.** ****::*******: * :* :*: * :.* :.:::* * *::*:**********:******:.*:::*..*::*:******************:*****:*: *** ****:************.**::****:***:****:****.* * ********************:*:***:* :: : :.: : :. :.:*:**::*:***:: ***.*::*:*: .. .. : . . :. . * . :.: . .: .: * ::. * .: : . * . *: * *.*.**.* * . :* ..: : . **:**.* **.* .* : :****:**:******** *** *****:*** **********:*:**:::****** **:*******:*: *.****:*::.*::**: * * * . ", "identical_positions": 398, "similar_positions": 221, "identity": "34.34%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-72", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VHW5-1", "uniprot_id": "CCG8_RAT", "id": "Q8VHW5-1", "name": "Voltage-dependent calcium channel gamma-8 subunit", "aln": "-----------------------------------------------------------------------------------------------MESLKRWNEERGLWCEKGVQVLLTTIGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAG-------------------------------------DDGPPHRGGSGSSEKKDPGG------------------------------------------------------------------LTHSGLWRICC-LEGLKRG--VCVKINHFPED--TDYDHDSAEYLLRVVRASSIFPILSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISANAGEPGPKRD-----EEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQ------------------------------------SRSDLLKAGGGAGGSG-----------GSGPSAILR----------------------------------------------------------------LPSYRFRYRRRSRSSSRGSSEASPSRDASPGG--PGGPG---------------------------------------------------------------------------------FASTDISMYTLS-RDPSKGSVAAGLASAGGGG------------------------------------------------------------GGAGVGAYGGAAGAAG------------GGG-----TGSERDRGSSAGFLTLHNAFPKEAASGVTVT--------------------------------VTGP--------------------------PAAPAPA--PPAPAAPAPG----------TLSKEAAAS-------NTNTLNRKTTPV----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VHW2-1", "uniprot_id": "CCG8_MOUSE", "id": "Q8VHW2-1", "name": "Voltage-dependent calcium channel gamma-8 subunit", "aln": "-----------------------------------------------------------------------------------------------MESLKRWNEERGLWCEKGVQVLLTTIGAFSAFGLMTIAISTDYWLYTRALICNTTNLTAG-------------------------------------DDGPPHRGGSGSSEKKDPGG------------------------------------------------------------------LTHSGLWRICC-LEGLKRG--VCVKINHFPED--TDYDHDSAEYLLRVVRASSIFPILSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISANAGEPGPKRD-----EEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQ------------------------------------SRSDLLKAGGGAGGSG-----------GSGPSAILR----------------------------------------------------------------LPSYRFRYRRRSRSSSRGSSEASPSRDASPGG--PGGPG---------------------------------------------------------------------------------FASTDISMYTLS-RDPSKGSVAAGLASAGGGG------------------------------------------------------------SGAGVGAYGGAAGAAG------------GGG-----AGSERDRGSSAGFLTLHNAFPKEAASGVTVT--------------------------------VTGP--------------------------PAAPAPAPAPPAPAAPAPG----------TLSKEAAAS-------NTNTLNRKTTPV----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WXS5-1", "uniprot_id": "CCG8_HUMAN", "id": "Q8WXS5-1", "name": "Voltage-dependent calcium channel gamma-8 subunit", "aln": "-----------------------------------------------------------------------------------------------MESLKRWNEERGLWCEKGVQVLLTTVGAFAAFGLMTIAISTDYWLYTRALICNTTNLTAGG------------------------------------DDGTPHRGGGGASEKKDPGG------------------------------------------------------------------LTHSGLWRICC-LEGLKRG--VCVKINHFPED--TDYDHDSAEYLLRVVRASSIFPILSAILLLLGGVCVAASRVYKSKRNIILGAGILFVAAGLSNIIGVIVYISANAGEPGPKRD-----EEKKNHYSYGWSFYFGGLSFILAEVIGVLAVNIYIERSREAHCQ------------------------------------SRSDLLKAGGGAGGSG-----------GSGPSAILR----------------------------------------------------------------LPSYRFRYRRRSRSSSR-SSEPSPSRDASPGG--PGGPG---------------------------------------------------------------------------------FASTDISMYTLS-RDPSKGSVAAGLAGAGGGG------------------------------------------------------------GGA-VGAFGGAAGGAG------------GGGGGGGGAGAERDRGGASGFLTLHNAFPKEAGGGVTVT--------------------------------VTGP--------------------------PAPPAPA--PPAPSAPAPG----------TLAKEAAAS-------NTNTLNRKTTPV----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QCW1-1", "uniprot_id": "E9QCW1_DANRE", "id": "E9QCW1-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------MVCEKGIQILLTIVGAFASFGLMTVAIGTDYWLYSRALICNST---ANN------------------------------------TQEDPHN-----KDKKDPGA------------------------------------------------------------------LTHSGLWRICC-LEGVKRG--VCSQINHFPED--ADFDHDGAEYVLRVVRASNIFPILSAILLLMGGVCIAASRFYKSKRNIVLGAGILFVAAGLSNIIGVIVYISAALGDISPKKD-----EDKKWQYSYGWSFYFGGLSFILAEMVGVLAVNIYIEKNKELRCR------------------------------------TRTDIFKS---------------------TTHAMLR----------------------------------------------------------------LPSYRFR--RRSRSSSR-STDPSRSRDPSPVGGPPGGKN---------------------------------------------------------------------------------FGMPPSALLSQGPISVSTLPNPHSRSALPGGD------------------------------------------------------------ISLYTLSRDPKLGGIG------------GLG-----APPLYGTVDRATLYQLHNCFPKEGGGGMMMS--------------------------------GTLPSLKSHNPSGVQNSSNSNA--------PLSNSVPSSQPPPFSSSTGERDRGMGTLDRLGKGDRES-------NSNTLNRKTTPV----------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2MGK8-1", "uniprot_id": "Q2MGK8_DROME", "id": "Q2MGK8-1", "name": "", "aln": "MRDYPSVPNVFRVASTHSINSENPYNNIRPANVICNTTERPPIAIHQLTTSASIEHSHPSQQAQHQQQQLLHHQQQHHHQQHSPYATLPRGQRLAPQQHQQAGVINTISGSIPATGFSSLAGSFSDLQLNNIGNHSSNSRSNHNSISNNRRQQQQQQQQQQQRLVPHLSRHQPAIEVQQTQQHQQTQQQHVQRQQQQERLASGGAGATDPQGGISNMTTVNGGYLWLITPVAASISVAIVIAALAGPQWLFTEEKLPNANYNGTANFKALDDGAYITKYTKSSLWILCTTLPGLDADSYNCVKIDYFSNEGYQPDPHDSTAAIPYTVTKSCPIFLAAGVFLVISFIVFLIPTCSHQNNLYYFSAGILFIVSGLVMLIGLIAYISILKAEIGSKLRPRSTLQPALIKVSYGQSFFLFVFGFIVTEFVGVLNIFLFINLQEVSYYSRLPCFSVANIHAKLKEGQHPLSDSYKRYKQPGITTASQEGLSSAGQGQQGHQSHHPTHQPHPTAQPPHGILRSGNSRLHQVYDAGRGHPGMTGQIGHSGQTQTLPGACRKHPNAGSNLNLYLHNDLERRFYFEKPAVSKCNLHSRSFAKSLNELCTDTSVSSTHVPAPLLPSAADPLPAPALFADLPQEFPLTRSVSTATEIYPASSSAPAPPSAQMKRKQQRNMATNTNTKISNNPPSSNSQMADQSRLCGLKRGLRKTKDELFQEFCRRAGMRSKPKNIYYISGGDEAEEEEQEDQAKREEVPDDPHRDDDDDADGDDHGFRQFNRMEEEHLYVVGDHAQLVVPRRTSMCVDSMGQPLRRLNSNLSLHTDLSFPGTGGYPGMRMSLPQPADLGQSRTLPRCFLRQSSDSLASQGYPLGSSQQRFSQLMLNQQQNRFVSSTLTLPQVVAPKSQVQWPTAIPSSPSNYSNGYQQHPQPIYPAPTSGSGAPGTTASVSGPPKFQRGYAFDDQQRRSSFVSDAFDLDEIERERRRSHASLFGMGQVRDPYDLINGTAV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : *:*: : * .:. :. .: *.*. : .. .** . *:*.** :* * *:. . * :*::*.:: **.: : .* * : : :.::*::. : . . :.:. :.*****:.:** :**:*.*** .: ..* : : *** **:: :.**::*.:*** : ::*: .. :: .: .: . .:** :.. .:: ::* .. .::.* * * *.. . : . : . . . . **. . . : . . * * . . . * ..* ::....: . * * : . .* :.:. : . * : : ::*: ", "identical_positions": 66, "similar_positions": 147, "identity": "6.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-73", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R553-1", "uniprot_id": "CSTN3_RAT", "id": "Q8R553-1", "name": "Calsyntenin-3", "aln": "----MTLLLVSLLLASLLQISSGNKANKHKPWIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAG-EICGFRLH----GSG-VPFKAVILDKATGEGLIRAKEPVDCEAQKEHTFTTQAYDCVDGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDNDGNIENTEKLQYSGEKLYKFTVTAYDCGKKRAADDAEVEIQVKPTCKPSWQGWNKRIEYAPG-AGSLALFPGIRLETCDEPLWN-----IQATIELQTSHVAKGCDRDNYSERALRKLCGAATGEVDLLPMPGPNANWTAGLSVHYSQDSSLIYWFNGTQAVQVPLGGPAGLGSGPQDGLSDHFTLSFWMKHSVTPSK--------GKKEEETIVCNTIQNEDGYSHYSLTVHGCRIAFLYWP-----LLESARPVKFLWKLEQVCDDEWHHYALNLEFPT-VTLYTDGISFD---------PALIHDNGLIHPPRREPALMIGACWSEEKNKEKEKGGENSTDTTSGDPLPIHHYFHGYLAGFSVRSGRLESREVIECLYACREGLDYRDFESLGKGMKVHVNPSQSLLTLEGDDVETFNHALQHVAYMNTLRFATPGVRPLRLTTAVKCFSEESCVSIPEVEGYVVVLQPDAPQ----ILLSGT-AHFARPAVDFEGPEGVPLFPDLQITCSISHQVEAKADESWQGTVTDTRMSDEIVHNLDGCEISLVGDDLDPERESLLLDMASLQQRGLELTN--RSAYLTIAGVETITVYEEILRQARYQLRHGAALYARKFRLSCSEMNGRYSSNEFIVEVNVLHSMNRVAHPSHVLSSQQ-FLHRG--------------------HQPPPEMAGHSLASSHRNSMVPS---------------AATLIIVVCVGFLVLMVILGLVRIHSLHRRVSGTGGPSGASADPKDPDLFWDDSALTIIVNPMESYQNQQTGVAGVAGGQQEEEDSSDSEAADSPSSDERRIIE-----SPPHRY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JH7-1", "uniprot_id": "CSTN3_MOUSE", "id": "Q99JH7-1", "name": "Calsyntenin-3", "aln": "----MTLLLVSLLLASLLQISSGNKANKHKPWIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAG-EICGFRLH----GSG-VPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGTNTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDNDGNIENTEKLQYSGEKLYKFTVTAYDCGKKRAADDAEVEIQVKPTCKPSWQGWNKRIEYAPG-AGSLALFPGIRLETCDEPLWN-----IQATIELQTSHVAKGCDRDNYSERALRKLCGAATGEVDLLPMPGPNANWTAGLSVHYSQDSSLIYWFNGTQAVQVPLGGPAGLGSGPQDGFSDHFTLSFWMKHSVTPSK--------GKKEEETIVCNTVQNEDGYSHYSLTVHGCRIAFLYWP-----LLESARPVKFLWKLEQVCDDEWHHYALNLEFPT-VTLYTDGISFD---------PALIHDNGLIHPPRREPALMIGACWTEEKNKEK-KGGENSTDTASGDPLLIHHYFHGYLAGFSVRSGRLESREVIECLYACREGLDYRDFESLGKGMKVHVNPSQSLLTLEGDDVETFNHALQHVAYMNTLRFATPGVRPLRLTTAVKCFSEESCVSIPEVEGYVVVLQPDAPQ----ILLSGT-AHFARPAVDFEGPEGVPLFPDLQITCSISHQVEAKADESWQGTVTDTRMSDEIVHNLDGCEISLVGDDLDPERESLLLDMASLQQRGLELTN--TSAYLTIAGVETITVYEEILRQARYQLRHGAALYARKFRLSCSEMNGRYSSNEFIVEVNVLHSMNRVAHPSHVLSSQQ-FLHRG--------------------HQPPPEMAGHSLASSHRNSMVPS---------------AATLIIVVCVGFLVLMVILGLVRIHSLHRRVSGTGGPSGASTDPKDPDLFWDDSALTIIVNPMESYQNQQTCVAGVAGGQQEEEDSSDSEAADSPSSDERRIIE-----SPPHRY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQT9-1", "uniprot_id": "CSTN3_HUMAN", "id": "Q9BQT9-1", "name": "Calsyntenin-3", "aln": "----MTLLLLPLLLASLLASCSCNKANKHKPWIEAEYQGIVMENDNTVLLNPPLFALDKDAPLRYAG-EICGFRLH----GSG-VPFEAVILDKATGEGLIRAKEPVDCEAQKEHTFTIQAYDCGEGPDGANTKKSHKATVHVRVNDVNEFAPVFVERLYRAAVTEGKLYDRILRVEAIDGDCSPQYSQICYYEILTPNTPFLIDNDGNIENTEKLQYSGERLYKFTVTAYDCGKKRAADDAEVEIQVKPTCKPSWQGWNKRIEYAPG-AGSLALFPGIRLETCDEPLWN-----IQATIELQTSHVAKGCDRDNYSERALRKLCGAATGEVDLLPMPGPNANWTAGLSVHYSQDSSLIYWFNGTQAVQVPLGGPSGLGSGPQDSLSDHFTLSFWMKHGVTPNK--------GKKEEETIVCNTVQNEDGFSHYSLTVHGCRIAFLYWP-----LLESARPVKFLWKLEQVCDDEWHHYALNLEFPT-VTLYTDGISFD---------PALIHDNGLIHPPRREPALMIGACWTEEKNKEK-EKGDNSTDTTQGDPLSIHHYFHGYLAGFSVRSGRLESREVIECLYACREGLDYRDFESLGKGMKVHVNPSQSLLTLEGDDVETFNHALQHVAYMNTLRFATPGVRPLRLTTAVKCFSEESCVSIPEVEGYVVVLQPDAPQ----ILLSGT-AHFARPAVDFEGTNGVPLFPDLQITCSISHQVEAKKDESWQGTVTDTRMSDEIVHNLDGCEISLVGDDLDPERESLLLDTTSLQQRGLELTN--TSAYLTIAGVESITVYEEILRQARYRLRHGAALYTRKFRLSCSEMNGRYSSNEFIVEVNVLHSMNRVAHPSHVLSSQQ-FLHRG--------------------HQPPPEMAGHSLASSHRNSMIPS---------------AATLIIVVCVGFLVLMVVLGLVRIHSLHRRVSGAGGPPGASSDPKDPDLFWDDSALTIIVNPMESYQNRQSCVTGAVGGQQEDEDSSDSEVADSPSSDERRIIE-----TPPHRY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PFP2-1", "uniprot_id": "CSTN3_DANRE", "id": "A0A8M9PFP2-1", "name": "Calsyntenin-3", "aln": "---MARMSFLSFLLFCLTSVAHGNKANKHKPWIETEYQGIVMENDNTVLLNPPLFALDKDAPLHYAG-EICGFRVHNGPGGSGSAQFEAVVLDRSTGEGLVRSKEPLDCESQKEHSFTIQAYDCGEGPDGTNSKKSHKATVHVRVNDVNEFSPVFVERRYEASVPEGRLFDRIVRVEAVDADCSPQYSQICFYDIITPNVPFTIDNDGNIKNTEPLDSKRQRVHSFWVTAFDCGKNRAQADAQVIVTVKPSCKPGWIGWTKRIEYTPG-SGSIPLFPNLHLETCEETVWN-----IQATVELQTSHIGKGCDRDSYSDRSVRRLCGAVRGEVDLLPPPSPATNWTAALPTLPSSDSSLVFSFNGSTHVAVVPDSVASAVSG------DHFTLQLWMRRGGASTQPPANQARGTRKEEETIVCSTVKNDDSYSHYSLSVHGCRLSLFYWP-----DVSAARPVKFLWKLEQVCDSEWHHLSLSVQFPS-VTLYVDGVTFD---------PALIHDNGAIPNPAPHQRLVIGACWEPE---EKPKDIVNNTMPENKDTGKFVSGYKGLLSGVTVRPGNVEPHSVVECLYACREGLDFGDLETLGSGMKVHVNPSQSVLVLEGDDIESFNRAVQQVTYRNSLRFATPGVRPLKLTTSLRCFSEESCLSLRQLEGYLVVLQPDAPQ----ISLSGVGPHLARPAAEFEGPQGVPLFPELRIVCSLSHAVNTAA----QGMEGGALMSDAVAHTLDGCEVQPLGEELNTEREELLVDMESLRERGLDIIN--TTAYIAITGAESISVYEDVLRSIHYRLAKGSARFERRFRLSCSEMNGRYTSNELTLEVNFLHSLDSLYHPSHLLASQQQFLHPS--------------------HHTG-ELSGHTLPNPHRNSVVPG---------------AATVIIMVCVGFLVVMVILGVFRIRSIHRRGEGARG------GGKEGGNQWDDSALTIIVNPMETYENRMGITTDMEGECEDEEEVVDS--PDDTSDDQRIIIKKEGRDSAPRRY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V498-1", "uniprot_id": "CSTN1_DROME", "id": "Q9V498-1", "name": "Calsyntenin-1", "aln": "MTFHKTFGYGCIVLICFELLFAGVETSSENDDEYLTQKEIILEKSYHGLIRENETLVEITPLIKVNEEKICNFHIL-----KKPYHEIPFKIELVNNLGILKARRTLNCENRKSYHFEICAIYCDGTP-------SNTANVHITVIDVNEYAPTFLEPSYVIEVDEGRLYNEILRVEASDKDCTPLFGDVCKYEILNNDEPFSIDNEGSIKNTEPLSHKASHNHILSVVAYDCAMKESAP-IMVSIKVRRVCETKFVGMPERIDYTSGSTESLQLFPNARLDLCDISCKNEEDLRIHSSIALKTKHISFGCDRDISN-------CTSGQKVKDLLP---HGAEWTKELSYDEGLEP--IFHFDGSTGVVVPATVIDHYDFS-----SQPFSILTLFRHNSQVEIN--------KHVKEHIVCSADDHKMNRHHMALFVRNCRLIFLLRKNFNEGDLNIFSPAEWRWKIPEVCDNEWHHYVLNVEDSSKVDLFIDGVRFENSIENRHSNPEVIDDWPLHAAHGVNTSLAIGACYQSLENRLK--------HGFNGDISEVKVSLNSVLTAEDIKCG----TTCAEHLLAPKP-LQSNNEKSYSDNSQIKENIEMNEIYISAKNKHDIEQFMRKVQYINTKQKPTVGRRNIEVLTTLNCKNE-SSLRLPPIETYIMVNEPIAPLGIDIDVVSASLETSDLTPPSYSPKIAISGTSNKLVSYQEIKLGVHILEKTCIDSVSKNNGKLEEKNHIDSCSVVVF-PSLNPDHEDIKIDGDESLSSSMDIKTNINKDGVEMIGKDTISNYINVLRSLVYSNKKPAYYLNRVFKLSCAQQSSQYKSGEYTLTLTVLHPKQTLFKSTNVLPSSLSKVNFIGNTDNETSFHRNSGSVNGNDNNQPTESKVYSYSLLHTNNVQEPKSHIHSFIHKAEGSHVTMLIILVSVFLAVLLCGVSIARLKNNQKYIEHHQP----CPKISDDGLIWDDSALTITINPMQADVTSDASSESENSESEDEEALKDGFTHINQLEWDNSNIFQQ---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::* .: ::...: : *::*:. *:. :: . :: :**.*:: . .. :: .. *:::::..::** :*.: * * * * *:.*.**: * ****::*.*:* * * **:*::.*:**** * **:* :.::* *:*:. : ** ***:*.*:*** *. . .: : : *.*:**. :.: * : *: *:. : * :**:*:.* : *: ***. :*: *: . * *:::: *:*.*:. ***** . * : **** ::** *. . :. :: *:*: * * . : *:: :::. :: :* ***.: .:. . * :* *:.**: :: :. *.:: **: :***.**** *.:: .: * *: **: *: * :*.* . * ****: * . * . :. *:. :: * * * * : *: : :: ... ::: * . . : :...: . ::: :::* * *: : .* * * :.: *::.* .* *.: : :* *::* :* ** :*. .. .:. .:. .: : . : . . : :*.*.: . .*:.::*.: :* . . .::: . . : : * ::*: * ::**. * : : * *:***:: ..:*.*.* : :..**. : : :.:::*.*. :: :: * :: . * *.: .: :**:*.* : *:: :.: *::. :: . .: . ******** :***:: . . . :::* *. . . :. * ", "identical_positions": 201, "similar_positions": 327, "identity": "19.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-74", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZUV5-1", "uniprot_id": "A0A8I5ZUV5_RAT", "id": "A0A8I5ZUV5-1", "name": "", "aln": "-------------MASVFMCGVEDLLFSGSR--FVWNLT------------VSTLRRWYTERLRACH-------------QMTEGRHCQVHLLDDRRLELLVQPKLLSRELLDLVASHFNLKEKEYFGITFIDDTGQENWLQLDHRVLEHDLPKKPGPAVLHFAVRFYIESISFLKDKNTVELFFLNAKACVHKGQIEVDSETIFKLAALVLQESKGDYTSDENARKDLKTLPVFPTKTLQEHPSLAYCEDRVIEHYLKIKGLTRGQAVVQYMKIVEALPTYGVHYYAVKDKQGLPWWLGISYKGIGQYDLQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTWYANSSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDDIAMDLTETGTQRVSKLVTLEAKSQFIMASNGSLISSGSQDSEGMEEQKREKILELKKKEKLLQEKLLKKVEELKKICLREAELTGRMPKEYPLNIGEKPPQVRRRVGTTFKLDDNLLPTEEDPALQELESNFLIQQKLVEAAKKLASEPDLCKTVKKKRKQDYTDAVKRLQEIENSINEYRIRCGKKPSQKAAVVPPEDIIPSESSSLSDTTTYDDPNDSFTLAGQRPSSVPHSPRILPPKS-LGIERIHFRKSSINEQFVDTRQS---------------REMLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPDSSSQHCRQRSGSLESQSHLLSEMDSDKPFFTLSKSQRSSSTEILDDGSSYTSQSSSEYYCVTPAAGPYYTTQTLDTRARGRRRSKKHSVSTSNSGSMPNLAQKDTLRNGVYSKGQDPPPSGYYIAGYPPYAECDLYYSGGYVYENDTEGQYSVNPSYQSSAHYGYDRQRDYSRSFHEDEVDRVPHNPYATLRLPR-KAAVKSEHITKNIHKAIVAEHLRGWYQRASGQKDQG-HSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTNASG-NWRTQLTTGLSEYENPVHSPYTSYYGNIYNPLPSPNRQYAESTPLDGTDGNQLEDSLESSEQRLFWHEDSKPGTLV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q920B0-1", "uniprot_id": "FRM4B_MOUSE", "id": "Q920B0-1", "name": "FERM domain-containing protein 4B", "aln": "-------------MASVFMCGVEDLLFSGSR--FVWNLT------------VSTLRRWYTERLRACHQVLRTWCGLRDVYQMTEGRHCQVHLLDDRRLELLVQPKLLSRELLDLVASHFNLKEKEYFGITFIDDTGQENWLQLDHRVLEHDLPKKPGPTLLHFAVRFYIESISFLKDKNTVELFFLNAKACVHKGQIEVDSETIFKLAALVLQESKGDYTSDENARKDLKTLPVFPTKTLQEHPSLAYCEDRVIEHYLKIKGLTRGQAVVQYMKIVEALPTYGVHYYAVKDKQGLPWWLGISYKGIGQYDLQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTWYANSSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDDIAMDLTETGTQRGSKLVTLEAKSQFIMASNGSLISSGSQDSEGMEEQKREKILELKKKEKLLQEKLLQKVEELKKICLREAELTGRMPKEYPLNIGEKPPQVRRRVGTTFKLDDNLLPTEEDPALQELESNFLIQQKLVEAAKKLASEPDLCKTVKKKRKQDYTDAVKRLQEIENSINEYRIRCGKKPSQKAAVVPPEDIIPSESSSLSDTTTYDDPNDSFTLAGQRPSSVPHSPRILPPKS-LGIERIHFRKSSINEQFMDTRHS---------------REMLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPDSSSQHCRQRSGSLESQSHLLSEMDSDKPFFTLSKSQRSSSTEILDDGSSYTSQSSSEYYCVTPAASPYYTTQTLDTRARGRRRSKKHSVSTSNSGSMPNLAQKDPLRNGVYSKGQDPPPSGYYIAGYPPYAECDLYYSGGYVYENDTEGQYSVNPSYRSSAHYGYDRQRDYSRSFHEDEVDRVPHNPYATLRLPR-KAAVKSEHITKNIHKALVAEHLRGWYQRASGQKDQG-HSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTNASG-NWRTQLTIGLSEYENPVHSPYTSYYGSIYNPLSSPSRQYAETTPLDGTDGSQLEDNLEGSEQRLFWHEDSKPGTLV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2L6-1", "uniprot_id": "FRM4B_HUMAN", "id": "Q9Y2L6-1", "name": "FERM domain-containing protein 4B", "aln": "-------------MASVFMCGVEDLLFSGSR--FVWNLT------------VSTLRRWYTERLRACHQVLRTWCGLQDVYQMTEGRHCQVHLLDDRRLELLVQPKLLARELLDLVASHFNLKEKEYFGITFIDDTGQQNWLQLDHRVLDHDLPKKPGPTILHFAVRFYIESISFLKDKTTVELFFLNAKACVHKGQIEVESETIFKLAAFILQEAKGDYTSDENARKDLKTLPAFPTKTLQEHPSLAYCEDRVIEHYLKIKGLTRGQAVVQYMKIVEALPTYGVHYYAVKDKQGLPWWLGISYKGIGQYDIQDKVKPRKLFQWKQLENLYFREKKFAVEVHDPRRISVSRRTFGQSGLFVQTWYANSSLIKSIWVMAISQHQFYLDRKQSKAKIPSARSLDEIAMDLTETGTQRASKLVTLETKSQFIMASNGSLISSGSQDSEVSEEQKREKILELKKKEKLLQEKLLKKVEELKKICLREAELTGKMPKEYPLNIGEKPPQVRRRVGTAFKLDDNLLPSEEDPALQELESNFLIQQKLVEAAKKLANEPDLCKTVKKKRKQDYTDAMKKLQEIENAINEYRIRCGKKPSQKATVLP-EDIIPSESSSLSDTTTYDDPSDAFTFPGQRSSSVPHSPRILPPKS-LGIERIHFRKSSINEQFVDTRQS---------------REMLSTHSSPYKTLERRPQGGRSMPTTPVLTRNAYSSSHLEPESSSQHCRQRSGSLESQSHLLSEMDSDKPFFSLSKSQRSSSTEILDDGSSYTSQSSTEYYCVTPVTGPYYTTQTLDTRTRGRRRSKKQNVSTSNSGSMPNLAQKDSLRNGVYSKSQEPPSSSYYIAGYTPYAECDFYYSGGYVYENDTEGQYSVNPSYRSSAHYGYERQRDYSRSFHEDEVDRVPHNPYATLRLPR-KAAAKSEHITKNIHKALVAEHLRGWYQRASGQKDQG-HSPQTSFDSDRGSQRCLGFAGLQVPCSPSSRASSYSSVSSTNASG-NWRTQLTIGLSDYETPAHSSYTSCYGNVYNPLPSPSRQYTEISQLDGTDGNQLEDNLESSEQRLFWHEDSKPGTLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AV01-1", "uniprot_id": "A0A8M3AV01_DANRE", "id": "A0A8M3AV01-1", "name": "", "aln": "MKEQRSGSAERVICVCVCVCSVTRLCNPGVRAAMVWGLVCVCVCVFRAAGFIWRLVFWAVGRMRCCQESVQTCFYLRHVYQMTEGRLCQVQLLDDRKLEMLVQPKLLSRELLDLVSSHFNLKEKEYFGFTYVDDTGQCKWLQLERRVLEHDFSKKSGPIALQFLVRFYIESISLLKEHTTVELFFLNAKSAIYNGDIEVESELVFKLAAHALQESKGDYTSDENTRADLKKFPVLPTKVLKEHPSLAYCEERVMEQYRLLKGISRGQAIVQYMTLVQSLPTYGVHYYEVKDKQGMPWWLGISYKGIGQYDHQDKVKPRKLFQWKQLENLYFREKKFAVEVNDPHRRAVTKRTFGQTGLVIHTWYATHSLIKTIWVMAISQHQFYLNRKQSKAKITTARSLGDIAVDLTENGASKMSKLS-AGVKNQLIMASNGSLVSTGSADSEMNDEQKKEKLAELRKKERDIQDILSQKLTELKEICLREAELTGKLPKEYPLIKGETPPHVRRRVGTAFKLDD-LFPYNEDPYLRNLESRFALQQKIVEAAKKLAAEPDISKLVRKKRRRNCLDAMQKLQEIEDEMNQYRLKKGQKPTQRASVIIADELAQSECSSLCDSLPLDDDDGGQRP---RSRSVQCSPCLSPPLSSSGLDFDPERRSSSSDTHHDRPLNRLDHEVQEPGHYYTPREVFSAQSSPCKTLSRMPKDPRSLPQTPVLPRNAYSSSQLRSDGHIRAFRHRSGSLESQSQLFHSHCANKSVFPLSPSRRSNSTEVLDDCSSYTSMSSMDFCLPCSATPPYR---TLDSHSHDYRLHRKVEIYG-NTGSMPNLVPQNSSS---YQQNHYGP-TAYYVAGYAG-FDYEPCSNGAYVYESEIEGHYNINPTYPAHGYQGRGRNRHYG----IEGLDNLSQNPYATVRPPRGRQGPLNEVLTKNMYRALVAEHLKGWYNRSAGHRDPGTYQLVYTYKYDRGSQHSLGYQTLPAPFSHSSRTNSFSSVSSTASGGGNWQNQLAVGLADGELPDGPLSAGAYSPAYSRSPTHSSRFPSEGAASHT----------SEPLEVFGAVASCSDTEN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* :*.* * .* * :**.*. : * * . *:*.*: ****** ***:*****:**:*******:*******:************:*::***** :****::***:**:.**.** *:* *********:**::.**********:.:::*:***:** :***** ***:*********:* ***.:*.:***.*:*********:**:*:* :**::****:****.:*::********* ******:*************** *****************************:**:* :*::*****:**.::****. ****:*************:********.:****.:**:****.*:.: *** .*.*:********:*:** *** :***:**: **:***: :*: * :*: ***:**********::****** **.**:*******:***** *:* :*** *::***.* :***:******** ***:.* *:***::: **:::*****: :*:**:: *:**:*:*:*: ::: **.***.*: . ** ... *. ** ** : ** * *:: *:** .: . * . **::*::*** ***.* *:. **:* ****.*******:*..:. : *:*********:*: . ::*..*.** *:**.***:*** ***** ** :: ..: ** ***::::. * :* .: *:******. ::. *.:.: * :.**:***. : : .*.****.: **:*.:**:* : .: * *:*.*. : :*.:.:*****:* ** : . .* :***:::*:*****:***:*::*::* * :. ::. *****:.**: * .* * ***:.*:****** :.* **:.**: **:: * * . :. *. *. .: . ::.. . * .. .:* * ..* ", "identical_positions": 551, "similar_positions": 275, "identity": "50.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-75", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2V1-1", "uniprot_id": "Q5U2V1_RAT", "id": "Q5U2V1-1", "name": "peptidylprolyl isomerase", "aln": "MGPRTHREPHVLGKLDGVPGRAHLEVRVVQTLERGLGRASPSGAPLEDVVIERYHIPRACPREVQMGDFVRYHYNGTFEDGKKFDSSYDRSTLVAIIVGVG-RLITGMDRGLMGMCVNERRRLIIPPHLGYGSIGLAGLIPPDATLYFDVVLLDVWNKEDTVQSTILLRPPYCPRMVRNSDFVRYHYNGTLLDGTAFDSSYSRGGTYDTYIGSGWLIKGMDQGLLGMCPGEKRKIIIPPFLAYGEKGYGTVIPPQASLVFYVLLIDVHNPKDTVQLETLELPQDCVRRAVAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYVGQGYIIPGMDQGLQGACIGERRRITVPPHLAYGENGTGDKIPGSAVLIFDVHVIDFHNPADPVEIKTLFRPPESCNETAKIGDFIRYHYNCSLLDGTRLFSSHDYEAPQEITLGANKVIEGLDRGLQGMCVGERRQLIVPPHLAHGENGARGVPGSAVLLFEVELISREDGLPAGYLFVWYQDPPASLFEDMDLNKDGEVPPEEFSSFIKAQVNEGKGRLMPGQDPDKTISDMFQNQDRNQDGKITAEELKLKSDEDQERI-HEEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61576-1", "uniprot_id": "FKB10_MOUSE", "id": "Q61576-1", "name": "Peptidyl-prolyl cis-trans isomerase FKBP10", "aln": "-MFLVGSSSHTLHRLRILP-----LLLLLQTLERGLGRASPAGAPLEDVVIERYHIPRACPREVQMGDFVRYHYNGTFEDGKKFDSSYDRSTLVAIVVGVG-RLITGMDRGLMGMCVNERRRLIVPPHLGYGSIGVAGLIPPDATLYFDVVLLDVWNKADTVQSTILLRPPYCPRMVQNSDFVRYHYNGTLLDGTAFDNSYSRGGTYDTYIGSGWLIKGMDQGLLGMCPGEKRKIIIPPFLAYGEKGYGTVIPPQASLVFYVLLLDVHNPKDTVQLETLELPQGCVRRAVAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYVGQGYIIPGMDQGLQGACIGERRRITVPPHLAYGENGTGDKIPGSAVLIFDVHVIDFHNPSDPVEIKTLSRPPENCNETSKIGDFIRYHYNCSLLDGTRLFSSHDYEAPQEITLGANKVIEGLDRGLQGMCVGERRQLIVPPHLAHGENGARGVPGSAVLLFEVELVSREDGLPTGYLFVWYQDPSTSLFEDMDLNKDGEVPPEEFSSFIKAQVNEGKGRLMPGQDPDKTISDMFQNQDRNQDGKITAEELKLKSDEDQERV-HEEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96AY3-1", "uniprot_id": "FKB10_HUMAN", "id": "Q96AY3-1", "name": "Peptidyl-prolyl cis-trans isomerase FKBP10", "aln": "-MFPAGPPSHSLLRLPLLQ----LLLLVVQAVGRGLGRASPAGGPLEDVVIERYHIPRACPREVQMGDFVRYHYNGTFEDGKKFDSSYDRNTLVAIVVGVG-RLITGMDRGLMGMCVNERRRLIVPPHLGYGSIGLAGLIPPDATLYFDVVLLDVWNKEDTVQVSTLLRPPHCPRMVQDGDFVRYHYNGTLLDGTSFDTSYSKGGTYDTYVGSGWLIKGMDQGLLGMCPGERRKIIIPPFLAYGEKGYGTVIPPQASLVFHVLLIDVHNPKDAVQLETLELPPGCVRRAGAGDFMRYHYNGSLMDGTLFDSSYSRNHTYNTYIGQGYIIPGMDQGLQGACMGERRRITIPPHLAYGENGTGDKIPGSAVLIFNVHVIDFHNPADVVEIRTLSRPSETCNETTKLGDFVRYHYNCSLLDGTQLFTSHDYGAPQEATLGANKVIEGLDTGLQGMCVGERRQLIVPPHLAHGESGARGVPGSAVLLFEVELVSREDGLPTGYLFVWHKDPPANLFEDMDLNKDGEVPPEEFSTFIKAQVSEGKGRLMPGQDPEKTIGDMFQNQDRNQDGKITVDELKLKSDEDEERV-HEEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PBG3-1", "uniprot_id": "A0A8M9PBG3_DANRE", "id": "A0A8M9PBG3-1", "name": "peptidylprolyl isomerase", "aln": "-------------------------MALTPALTVLFVVIYAVCCQLEDVIIDRYFIPAFCPREVQIGDYVRYDYNGTFKDGRKFDSSLNKGFPFIGQVGVESKVIPGLDKGVQGMCVNERRKITVPPHLAYGVLGSGSVIPPETTLVFDVHLLDLWNKEDKVQIRTIYRQQKCKRKVMPTDFVRYHYNGSLLVGNIFESSYLQNTTYDTYVGSGSLIKGIEEGITGMCVGERRSIIIPPFLAYGDKGYGTKIPPYATVIFDVLLVDLFNVKDDINVEVQMIPQPCRRKAVLGDFIRYHYNATFQDGTIFDSSYARNSTYNTFIGMGHVIAGIDKALQGVCVGEWRRVTVPPHLAYGETGSGELIPGSAVLIFDMHIIDFHNPKDQVHINVTNKP-AACNLTSDANDLILYRYNCSLLDGTRLYSSDDYPEPPRVILGQGKLISGLDEGLHGMCVLERREITVPPHLAHGANDAMGIPTSAVLLFEVELLQLQKGVPEGFLFIWLHDSPEPLFPAMDMNQDHKVLLEEFAAFIMLQVAEGRGRIHPGIDSDKALKEMFRNQDRNTDGKITEDELNIIVNEEKEVVTHMEL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: : . ****:*:**.** ******:**:***.*****:**:***** ::. . *** ::*.*:*:*: ********:: :****.** :* ..:***::** *** ***:*** *.** : * * * * *********:** *. *:.** :. *****:*** ****:::*: *** **:*.**********:***** *** *:::* ***:*:.* ** :::*. :* * *:* ***:*****.:: ***:*****:** ****::* *::*.*:*:.***.*:** **:*:********.*:*: *********::*:****** * *.*.. :* ** *:. .*:: *:*********:*::*.** * . ** .*:*.*** **:**** ***:: ******** ..* *:* **********:. :.*:* *:**:* :*.. ** **:*:* :* ***::** ** **:**: ** *.:*:: :**:***** ***** :**:: :*::* : * **", "identical_positions": 311, "similar_positions": 141, "identity": "52.8%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-84", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5TF21-1", "uniprot_id": "MTCL3_HUMAN", "id": "Q5TF21-1", "name": "Microtubule cross-linking factor 3", "aln": "MSQPPIGGAAPATAAASPAAAATEARLHPEGSSRKQQRAQSPARPRDSSLRQTIAATRSPVGAGTKLNSVRQQQLQQQQQQGNKTGSRTGPPASIRGGGGGAEKATPLAPKGAAPGAVQPVAGAEAAPAATLAALGGRRPGPPEEPPRELESVPSKLGEPPPLGEGGGGGGEGGGAGGGSGEREGGAPQPPPPRGWRGKGVRAQQRGGSGGEGASPSPSSSSAGKTPGTGSRNSGSGVAGGGSGGGGSYWKEGCLQSELIQFHLKKERAAAAAAAAQMHAKNGGGSSSRSSPVSGPPAVCETLAVASASPMAAAAEGPQQSAEGSASGGGMQAAAPPSSQPHPQQLQEQEEMQEEMEKLREENETLKNEIDELRTEMDEMRDTFFEEDACQLQEMRHELERANKNCRILQYRLRKAERKRLRYAQTGEIDGELLRSLEQDLKVAKDVSVRLHHELENVEEKRTTTEDENEKLRQQLIEVEIAKQALQNELEKMKELSLKRRGSKDLPKSEKKAQQTPTEEDNEDLKCQLQFVKEEAALMRKKMAKIDKEKDRFEHELQKYRSFYGDLDSPLPKGEAGGPPSTREAELKLRLRLVEEEANILGRKIVELEVENRGLKAELDDLRGDDFNG-SANPLMREQSESLSELRQHLQLVEDETELLRRNVADLEEQNKRITAELNKYKYKSGGHDSARHH----DNAKTEALQEELKAARLQINELSGKVMQLQYENRVLMSNMQRYDLASHLGIRGSPRDSDAESDAGKKESDDDSR--PPHRKREGPIGGESDSEEVRNIRCLTPTRSFYPAPGPWP-KSFSDRQQMKDIRSEAERLGKTIDRLIADTSTIITEARIYVANGDLFGLMDEEDDGSRIREHELLYRINAQMKAFRKELQTFIDRLEVPKSADDRGAEEPISVSQMFQPIILLILILVLFSSLSYTTIFKLVFLFTLFFVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NZL0-1", "uniprot_id": "MTCL3_MOUSE", "id": "Q6NZL0-1", "name": "Microtubule cross-linking factor 3", "aln": "MSQPPSGGAAPAATSASAAAAATEARMHPEGCSRKQQRAQSPARPRDNSLRQTAGATRSPLGVGPKLNSVRQQQLQQQQQQGNKITGRSTSGTGSRGLGGGAEKAVPSIPKGAVPGAVQPAPGAEGSPAAILASVSFRRSGQPEEAPREIESGPSKVGEPPPLG-GVGGGGEGGGAGGGPGDREGGAPQPPPPRGWRGKGVRATQRGSSVAEGVSPSPPTAATSKTPGPGSRNSGSGSTGSGSGGGGSYWKEGCLQSELIQFHLKKERAAAAAAAAQMHTKNGGGGS-RSSPVAGAPAICEPLVVPSSSPMAAAAEGPQQSAEGNGSGGAMQAAAPPSSQPHSQQLQEQEDMQEEMEKLREENETLKNEIDELRTEMDEMRDTFFEEDACQLQEMRHELERANKNCRILQYRLRKAERKRLRYAQTGEIDGELLRSLEQDLKVAKDVSVRLHHELENVEEKRTTTEDENEKLRQQLIEVEIAKQALQNELEKMKELSLKRRGSKDLPKSEKKAQQTPTEDDNEDLKCQLQFVKEEAALMRKKMAKIDKEKDRFEHELQKYRSFYGDLDSPLPKGEAGGPPSTREAELKLRLRLVEEEANILGRKIVELEVENRGLKAELDDLRGEDFNG-SSNPLMREQSESLSELRQHLQLVEDETELLRRNVADLEEQNKRITAELNKYKYKSSGHDSSRHH----DNAKTEALQEELKAARLQINELSGKVMQLQYENRVLMSNMQRYDLASHLGIRGSPRDSDAESDAGKKESDDDSR--PPHRKREGPIGGESDSEEVRNIRSLTPTRSFYPTPGPWP-KSFSDRQQMKDIRSEAERLGKTIDRLIADTSTIITEARIYVANGDLFGLMDEEDDGSRIREHELLYRINAQMKAFRKELQTFIDRLEVPKSADDRGAEEPISVSQMFQPIILLILILVLFSSLSYTTIFKLVFLFTLFFVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58HIU8-1", "uniprot_id": "A0AC58HIU8_DANRE", "id": "A0AC58HIU8-1", "name": "", "aln": "--------------------MESVENMKQQ---QQQQRASSPGRFKDS---PTKAASKS----------------GCSKASASKTGGKSSRSNSPVTVHTGKDRHAG---KGAA--AVHASGAESPTLRRAEKGRSTERSGSSEE--------PYAAAEEPLLG----------------------------------ADVVSDQPSSS-----KPSPGKRESSKADG------GKQAAKSAVGCGPGFWREGCLQSELIQFHMNKS----LKKDSGMTTKTP------SSPVTE----------------------PQRPPED------TRRPAEPLPEPD-------QELEEEIERLQDENDFLKHEIDEMRAEMDEMRDTFYEEDACQLQDMRRELERAHKNCRILQYRLRKAERKRMRYAETGEIDSELLRSLEQDLKVAKDVSVRLHNELENVEDKRARTDDENERLRQQLIEVEVTKQALQNELDKTKDLSLKRRG-KDVQKSEKRTPQTPTEEENEDLKCQLAFIKEEAVLMRKKMAKIDKEKDRLEQELQKYRSFYGDVDSPLPKGEAGGPPTTRESELKLRLRLVEEEANILGRKIVELEVENRGLKAELDDLRGDELTGGAADSSSREQSEALSELRQQLQLVEDEAELLRRNLADVEEQNTKMTSELNKLKYKAGSHEGSRYSSSAVDGAKLEALQEELKAARLQINELSGKVMQLQYENRVLLSNMQRYDLASHLGIRGSPRDSDAESDCGRRESDDDCSRLTPHRKREGPVGGESDSEEVRNIRCLTPTRSLYTPEGRFLSRSFKDRQQMIDIRMEAERLSRTIDRLIADTSTIIAEARVYLNNGELFGRLDDEEEGGRIREHELLYRINAQMKAFRKELQNFIDRLEVPK-PEDRESEEPLS---MFQPIILLILILVLFSSLSYATIFKLVFLFTLFFVL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:: : ::****.**.* :*. * .*::* .: ...* .:: . * :: . ***. **:. . . : . . .*.* .** * .* * ** .* : * ..* .*** . :.*: * *. : .. * * .:*:************::*. : * :*. ****: **:..*. : .* * .:*. ::::**:*:*::**: **:****:*:*********:********:**:*****:*****************:***:*****.*********************:******:**: *:****:*********::********:* *:******* **: ****:: *****::******** *:****.***************:*:***********:*************:***:***************************************:::.* :::. *****:******:*******:******:**:****.::*:**** ***:..*:.:*: *.** *******************************:**************************.*::*****. .********:*************.******:*.. * : :**.***** *** *****.:*************:***:*: **:*** :*:*::*.***********************.********* .:** :***:* ********************:***************", "identical_positions": 541, "similar_positions": 166, "identity": "56.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-86", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AY71-1", "uniprot_id": "CF418_RAT", "id": "Q6AY71-1", "name": "Cilia- and flagella-associated protein 418", "aln": "MAKDLDELLDEVETKFCRLDPLRLDLGERPKGGSGGGGTHSGDRNGAQEKDTLRSTETFKKEDDLDSLINEIFEEPNFDKKSFQKFKSKSSSNTSVRAPIQGLSKSCSPVYLSGSAIPCGIGTNTSQRACDRLRCVACDFQIVSYNDYMWDKSCDYLFFRNNMPEFHKLKTKLIEKKGARAYACQCSWRTVEELTDLQADHELRWVCGKH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UJP5-1", "uniprot_id": "CF418_MOUSE", "id": "Q3UJP5-1", "name": "Cilia- and flagella-associated protein 418", "aln": "MAKDLDELLDEVETKFCRLDPLRLDLGERPKG-DGGGGSHSGDRNGAQEKETLRSTETFKKEDDLDSLINEIFEEPDFDRKSFQKFKSKSSSNTCVRAPMQGVSKSCSPVYLSGSAIPCGIGTNTSQRACDRLRCVACDFRIVSYNDYMWDKSCDYLFFRNNMPEFHKLKTKLIEKKGARAYACQCSWRTVEELTDLQTDHQLRWVCGKH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96NL8-1", "uniprot_id": "CF418_HUMAN", "id": "Q96NL8-1", "name": "Cilia- and flagella-associated protein 418", "aln": "MAEDLDELLDEVESKFCTPDLLRRGMVEQPKG--CGGGTHSSDRNQAKAKETLRSTETFKKEDDLDSLINEILEEPNLDKKP-SKLKSKSSGNTSVRASIEGLGKSCSPVYLGGSSIPCGIGTNISWRACDHLRCIACDFLVVSYDDYMWDKSCDYLFFRNNMPEFHKLKAKLIKKKGTRAYACQCSWRTIEEVTDLQTDHQLRWVCGKH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0DOC8-1", "uniprot_id": "CF418_DANRE", "id": "P0DOC8-1", "name": "Cilia- and flagella-associated protein 418", "aln": "MADDLDDLLDEVESKFCCNTSESKQTSRVMKH-----TDQKCDNLEERKLPRKQGRKRVENEIDIDAMLHEILDD-DVDTPT----STHEPSPAKASSSAQTISKKCCPVFLGGSSVAHGIGTSVSERACNRLRCTYCDFSVITFDDHEWDSSCDYLFFRNNMPDYHKLKVHLRRRAGVRAYACQCSWISILTLSHLREQPQLKWVCGKHRA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.***:******:*** . * :. *. : :. : .::* *:*::::**::: :.* . .::... : . :. : :.*.*.**:*.**::. ****. * ***::*** *** :::::*: **.************::****.:* .: *.********* :: ::.*: : :*:****** ", "identical_positions": 81, "similar_positions": 71, "identity": "38.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-87", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62187-1", "uniprot_id": "TTF1_MOUSE", "id": "Q62187-1", "name": "Transcription termination factor 1", "aln": "----------------------------MKGGTSKFKTHTETLYKKKKWSSVSEKRPQKCPSQCLE-----SKQPQVSVLGKRRRASQTPAQETLE--------SEWPQKAKRKK-RRREPQTPAQET------LESEWPQKAKKKKRRGEPQTPTQESLESEQPPVSLLGKRRRESQTPAQENSESEQPRKAKRRRKKRKGSQQPTSSLLKTPETFLKAKKTTSAHKKKKNSVLEVDMETGIILVDKENMENLLETSRKDVDIVYVDMSKGQRSAKVRETGELPAA-----KPQEHGCRELLGDVRSRKKQKHLQKVAPWDVVQGSQP-ESISLPPSEPLSSEDLEGKSTEAAVFCKK-KSKKNVFRS--QELEPIPDSLDDSETISERLDSTHHGGAVGAGEECESTKESHSIKKKSKKKKHKSVALA-TSSDSASVTDSKAKNALVDSSEGSGAVREEDVDHRPAEAEAQACSTEKHREAMQRLEPTHEEESNSESASNSAARHISEDRRESDDSDVDLG-SAVRQLREFIP--DIQERAATTIRRMYRDDLGRFKEFKAQGVAIRFGKFSAKENKQIEKNVQDFLSLTGIESADKLLYTDRYPEEKTLITNLKRKHAFRLHIGKGIARPWKLVYYRAKKIFDVNNYKGRYNEEDTKKLKAYHSLHGNDWKKIGAMVARSSLSVALKFSQIGGTRNQGAWSKAETQRLIKAVEDVILKKMSPQELRELDSKLQEDPEGRLSIVREKLYKGISWVEVEARVETRNWMQCKSKWTEILTKRMTHGGFVYRGVNALQAKITLIERLYELNVNDANEIDWEDLASAIGDVPPPFVQAKFYKLKAACVPFWQKKTFPEIIDYLYKNSLPLLKEKLDKKMKKKDGQIQTPAAPKQDFLFKDIFHCDDDSDEGSPEEPSASDVQ-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A1Z7-1", "uniprot_id": "D4A1Z7_RAT", "id": "D4A1Z7-1", "name": "", "aln": "MRSKTEVSTVFPPHNTSGLKDECYTISGMEGG--KFKTHTATLHKKKKWSSVSEKRLQKWPSQHLE-----SEQPQVSVRKKRRRESQTPAQESLE--------SEQPWKAKKKKKRRRESQTPAQES------LESEQTPMSMLGKRRRESQTPAQENLESEQPWKAKKKKRRREYQTPAEESLESEQPWKAKRKKKKEKESQQLTSSLLKNSETFHKAKKTTAAHKKKKNSVWEVDMETGIILVDKENMENLLETSRKDVDIVYVDMSKGQRSAKVNETEELPMA-----ETQKRDCRELHSDIRSKKNQKHPQKIAPQDAIQGTQP-ERISLPQSESLSPVDLEGKNTKIAVFCKK-KSKKKVFRS--QELEAVSESLVSSETIPESLDSAHHGGEDETEEEGESIKESHRIRKKSKKKKHKSVTLA-TSGDSVSVLDSTAESALVDSPEGSGTLREEDVDHGSTEAEAQARPTEKHRKEIQRLEPTHEE-SNLESASNSATRCVSEDRRDSDESDVDLG-SAVRQLQEFIP--DIQERAATTIRRMYRDDLGRFKEFKAQGVAIRFGKFSVKENKQIEKNVQDFLSLTGIESADKLLYTDRYPEEKSLITNLKRKHAFRLHIGKGIARPWKLVYYRAKKIFDVNNYKGRYNEEDTKKLKAYHSLHGNDWKKIGAMVARSSLSVALKFSQIDGDRNHGTWSKAETQRLIKAVEDVILKKMSSQELRELDSRLQEDPEGRLSIVREKLYKGISWVEVEARVETRNWMQCKSKWTEILTKRMTHGGFVYRGVKALQAKITLIERLYELNVNDANEIDWEDLAGAIGDVPPPFVQAKFYKLKAACVPFWQKKTFPEIIDYLYENSLPLLKEKLAKKMKKKDSQIQKPTAPKQNFLFKDIFHCDDDSDEGGLEEPSTSDTQ-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15361-1", "uniprot_id": "TTF1_HUMAN", "id": "Q15361-1", "name": "Transcription termination factor 1", "aln": "----------------------------MEGESSRFEIHTPVSDKKKKKCSIHKERPQKHSHEIFRDSSLVNEQSQITRRKKRKKDFQHLISSPLKKSRICDETANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDVDVVCVDMSIEQKLPRKPKTDKFQVLAKSHAHKSEALHSKVREKKNKKHQRKAASWES--QRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKSRPRQKKTQACLASKHVQEAPRLEPANEE-HNVETAEDSEIRYLSADSGDADDSDADLG-SAVKQLQEFIP--NIKDRATSTIKRMYRDDLERFKEFKAQGVAIKFGKFSVKENKQLEKNVEDFLALTGIESADKLLYTDRYPEEKSVITNLKRRYSFRLHIGRNIARPWKLIYYRAKKMFDVNNYKGRYSEGDTEKLKMYHSLLGNDWKTIGEMVARSSLSVALKFSQISSQRNRGAWSKSETRKLIKAVEEVILKKMSPQELKEVDSKLQENPESCLSIVREKLYKGISWVEVEAKVQTRNWMQCKSKWTEILTKRMTNGRRIYYGMNALRAKVSLIERLYEINVEDTNEIDWEDLASAIGDVPPSYVQTKFSRLKAVYVPFWQKKTFPEIIDYLYETTLPLLKEKLEKMMEKKGTKIQTPAAPKQVFPFRDIFYYEDDSEGEDIEKESEGQAPCMAHACNSSTLGGQGRWII", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B2X7-1", "uniprot_id": "A0A8M3B2X7_DANRE", "id": "A0A8M3B2X7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDEMQSDSPNNVDGE-----------------------------------------------------------------------------KMKKKKISKTTEQHELTESPQEQTEKRRKKKKKKRRDSTTECDDDLQTDTG-----KKKKRRKLDNEGETSVMDDGVSDQHEAQTQELPGSSEEKTSRR-----LKARVSATQTSHAEMTEEEQTDTETEHEEEPNTSDDEESGPPDVVIGTGWRKSRKIPVDLKLLAELKEFCPNTAIESQSDTEINKMIKYDLPRFREFKKQGIAMRHGRFSKAENEKLRQNVSDLLALTQLKDAVMLFHPKRFLNEEMKLAELKRMYGFYQKIAEGIPRPCHDVYTRGKKMFDHRHYKGNFTEEEDKRLLKYYNLYGPNWKKISEKTGRSSFSLRKRFPQISSVKRKGPWTPEEVQRLLRAVREHVLSVLKSANPNKKKPKR---------VRREILYENLPWTTIADKVETRCYRQCREKWMSILFTRMSSG-TTFRGKAGLLAKIRLIKAMYEMQVEDVADIDWESLTAAFGNVPPAHVQKMWRKIKNYYLPDWNSRSFKDNVSHLHKNILPCLVS-SCKGFDVNAVKVEQKELFRLSKIFKDIEEDGQDIEEDGQDIEEDGRDGDEETGEQENNSFN------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .: . * **: . :: * . . : . . . : . **.*::* . : . .*. * . . * .* * . : . :*: :. : *. :** * . .:* : . .. . :. . : :*:** * *:.:: : *.:* : ** **:*** **:*::.*:** **:::.:**.*:*:** ::.* *::..*: :*: :::*** :.* :*...*.** : :* *.**:** .:***.:.* : ::* *:.* * :**.*. ..***:*: :*.**.. :.:*.*: *.::*::**.: :*. :.. : .: ..: : ** **:.:.*. : :*:** : **:.** .** .**: * : * .* **: **: :**::*:*. :****.*:.*:*:***..** : ::* :* *:.::* : :.:*::. ** * . * :. : ::: : *:** :* : . : . . ", "identical_positions": 142, "similar_positions": 204, "identity": "15.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-92", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H329-1", "uniprot_id": "E41LB_HUMAN", "id": "Q9H329-1", "name": "Band 4.1-like protein 4B", "aln": "MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSALPAAPGGSVFPAGGGPLLTGGAAVHISAAGAAKATLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSAQVAHWLDHAKPIKKQMKIGPAYALHFRVKYYSSEPNNLREEFTRYLFVLQLRHDILSGKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAMEFDIFQRWKECRGKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFEGANKIGLFFWPKITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPGNSKSNRSDFIRLGSRFRFSGRTEYQATHGSRLRRTSTFERKPSKRYPSR------------------RHSTFKASNPVIAAQLCSKTNPEVHNYQPQYHPNIHP--------------SQPRWHPHSPN---VSYPLPSPVLSSSDRLPFGIEENGGTPFLTAASGRHHHQHQHQHQH-----------------------------QHHSNYSLSLTLENKEGPLRSPNSSSKSLTKLSPGTPALFS---EAAAHLKKLELETVKAAGPWPPLHIN----------------------INKAEEKKVSEKTLQTPLLPSPVADHVKCNILKAQLENASRVNIQGGKEESPFVNINKKSSLQDASVRSPIPIRVETAQPAVEKPEIKPPRVRKLT----RQYSFDEDDLPPDLAEAVGVTT-----STTTNTTTAATQVSVPLPSPKVQNVSSP--HKSEGKGLLSPGAKSPSDRGGAFTLEPGDLLMDFTEATPLAEPASNPHCAHSRCSPPLSLPMKEETTGVCMYPPIKTRLIKTFPVDTMNPFPDTFTTGPQFTADFRDSKLQCCPGPTSPLIPAATLRPLTETVSTVQTIYTTRKPVSLAASAETLRQELEREKMMKRLLMTEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JMC8-1", "uniprot_id": "E41LB_MOUSE", "id": "Q9JMC8-1", "name": "Band 4.1-like protein 4B", "aln": "MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSVLPAAPGGSVFPAGGGPLLTGGAAVHISASGAAKATLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSAQVTHWLDHAKPIKKQMKVGPAYALHFRVKYYSSEPNNLREEFTRYLFVLQLRHDILSGKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAMEFDIFQRWKEYRGKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFEGANKIGLFFWPKITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPSNSKSARSDFIRLGSRFRFSGRTEYQATHGSRLRRTSTFERKPSKRYPSR------------------RHSTFKASNPVIAAQLCSKANPEVHNYQPQYHPDVHP--------------SQPRWRPHSPN---VSN----HSICKQNKPCF---QDDRPHWKTSASGDGSHFDYVQDQN-----------------------------QRNLGGAYSVTYR------------DKLMTAL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B2RYE5-1", "uniprot_id": "E41LB_RAT", "id": "B2RYE5-1", "name": "Band 4.1-like protein 4B", "aln": "MLRFLRRTFGRRSMQRYARGAAGRGAAGLGDERDGGPRGGPAAAASSSVLPAAPGGSVFPAGGGPLLTGGAAVHISASGAAKATLYCRVFLLDGTEVSVDLPKHAKGQDLFDQIVYHLDLVETDYFGLQFLDSAQVTHWLDHSKPIKKQMKVGPAYALHFRVKYYSSEPNNLREEFTRYLFVLQLRHDILSGKLKCPYETAVELAALCLQAELGECELPEHTPELVSEFRFIPNQTEAMEFDIFQRWKEYRGKSPAQAELSYLNKAKWLEMYGVDMHVVRGRDGCEYSLGLTPTGILIFEGANKIGLFFWPKITKMDFKKSKLTLVVVEDDDQGREQEHTFVFRLDSARTCKHLWKCAVEHHAFFRLRTPSNSKSARSDFIRLGSRFRFSGRTEYQATHGSRLRRTSTFERKPSKRYPSR------------------RHSTFKASNPVIAAQLCSKTNPEVHNYQPQFHPNVHP--------------SQPRWRPHSPN---VSN----HSTCKQNKPSF---QDDRPHWKASASGDDGHFDYVHDQN-----------------------------QRNLGGAYSVTYR------------DKLMTAL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2B4V0-1", "uniprot_id": "A0A8M2B4V0_DANRE", "id": "A0A8M2B4V0-1", "name": "", "aln": "MMGFLRRTFSRRS-KRNARPPS--EVDGTGNVRGG-----------NAVLQAHQQQVIHAP---TVVTGGAVVHIPAAGNSKDAITCRVLLLDGSDVNVELPKHAKGQDLFDQIMYHLDLVEADYFGLQFMDPEQVAHWLDAAKPIKKQIRHGPPYRLFFRVKFYSSEPNNLHEEFTRYLFVLQLRQDILSGKLKCPYDVSVELGAYCLQSELGDCDPLEHSILLVSEFRFSPKQTEIMEADIYRKWVECRGMIPSQAELNFLNKCKWLEMYGVDMHFVKGRDGGEYALGLTPTGILVFEGSSKIGLFFWPKITRLDFKRNRLTLVVVEDDEKGREQEHTFVFQLSSSHECKHLWKCAVESHAFFRLRQPTHNKTSRSDFTRLGSRFRFSGRTEYQATHSGKVRRASTFERRPSKRYPSR------------------AQSMVKAMTPAKHPHLSAQTSPEPS--LKPYKHNIPI--------------AQDPWQRSHPPPSLTSPLYIQPMELGHTPPPHSFPLSAADTRRFSVEENEAPHSGKIHRC-----------------------------YHHHGYEKQEPLC-----------LTTAKPKAWVVSPALSD---ELDRALQN-QLEAEPAA--WPALHIN----------------------IDMAEEKPLSEKSLPS--SPAVLQEQLKSNISKRATQSDS-------------GNSKGNSSSGDQTDRYPSSSQ-DSGSSSLNIEKPRVDRRKRLV----RQFSFNHSDED-DLPEALAAIS-----SQCS------------------MGKSSS--NSSLDKQVQPP-----------------------------------------------------------IYPPQKD-----------------------TSRLEHDSSPLFFPSPVPHLLPYATHTQ----------------------SSEDLR--MEREKLLRALLMTEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFU8-1", "uniprot_id": "Q9VFU8_DROME", "id": "Q9VFU8-1", "name": "Moesin/ezrin/radixin homolog 1", "aln": "MLRFLSRRKVRNNYVDNSREGGGATSSAVG--------------------VAGGGGAITSG-------GSSQIKPQRIVVNKNKIDCRVILLDNTDLSIELSKKALGSFLYEQVFYALDIIEKDYFGLQFMDANHVKHWLDPTKPIKKQVKIGPPYTFRLKVKFYSSEPNTLREELTRYLFFLQLKQDLLEGRLDCPEDKATELCALALQSELGDYDNQEHSAATVSEFRFVPEQTEDLEIAILDEYKTCRGLTPAQAETAFLNKAKWLDMYGVDMHTVLGKDGCEYHLGLTPTGILVFERDQKIGLFFWPKISKLDFKKKKLTLIVIEDDDEGREQEHTFVFRLYNEKACKHLWKCAVEHHTFFRLRAPVKGPSARQNFFRMGSRFRYSGRTEFQTTQQSRARRTVQFERRPSQRFASRQSHLLRERQKASQEAAVSAVASVNARAAAAAAAAAASQSPAPATPLVSSQVSTPTPNNDNNNDAFDSLISTDQFITVTPSPSVLTVIQNSAIIEPDAACSGSISSSSQAAANFASLGRNSLKSNFSNEDPAYSKIGSIGKASGLTVKLDPDYTPPYSPNATKNFDETNPFRNATSSHHGSFGKASISSGQLSVKSGLSDKDRELDSLLKSIVKDPSPSVLANEAINDANSIRVTINKTFDMDHNTETLKRLSNANEKPNNQVKLANVNTTALPPGNIKCNILKARVEEELGAGGNAKLTNQMFVPAAHSSNMHTSNTNSSNNHAHSDGPDSLNATYISVGGDKLTLSIPEQKPSTGSSSSSSTSSTATTTTNGNGPYSNATFVSGFSAPLTPPSSLPANLNNTGSGCNTTLTSVTTISTPSSPTATVSTTASESVAPALSNASAAEILINEIFINNIINNNASGSITAETAAKPAGSSTPSAGTLLFSTLSEQERLESQKTNQQMNQSLNLNQNHSEVDAP-PSEKKTPSNYPDSSRIPFPSSSNSKDMVSPWLVSSEVVSAPKGRESAIIRKSVITTQL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ** * *.. :* . . * * : . *.: :: * : ***:***.:::.::*.*:* *. *::*:.* **::* *******:*. :* **** :******:: **.* : ::**:******.*:**:*****.***::*:*.*:*.** : :.** * .**:***: : **: ****** *:*** :* * .: ** *:*** :***.***:******* * *:** ** *********:** .**********:::***:.:***:*:***::**********:* . : ********** *:***** * :. : *.:* *:*****:*****:*:*: .: **: ***:**:*:.** : .:* .. . .:. .* : . : : * : . : .. . . . . ", "identical_positions": 207, "similar_positions": 124, "identity": "20.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100921-93", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9V3N9-1", "uniprot_id": "Q9V3N9_DROME", "id": "Q9V3N9-1", "name": "", "aln": "MAQRLHLALVGVVLLNATASFAWKPIVGGGSG------ISGGTAAYSLKQSHPGAASSSHEISTSFSQFGGD----------KETTEVEDELLLGRAAIVNGVDSSAAVSHPISFADHLEDQYESYSIEDEAPKEPLAFPRSPVYGSDRCSVKKFAFNQDGEVEYGNPMPELDQFTICFWMR------FTNHSGDHVLLTYEAGKEPREVQIWVANAQ-----NSSFLSMAIKGQQMYRLNYPLKMRQWHHMCSSWNGKTGEWQAWLKAERIGRGFHNSLVGHKIPANGKLRSGGSSVTGEVSHGLHFEMTLVQVYRVALSAGKAHRDHKHHHVHHFDHEGQEVSSTTR------APPSINRPQPMHTLLASGQIPTRVRINLANPPPTASGAPAPGAAGAPTDSAQQAITINTNFVNGQINAGSRLVAQQLLG--LSPPSGLQPSGGGKRFQMLSNSAN--VQFIDETETHIQFKRNTDATKKVQKRGLVLLDDGSVVDDGVGSGTDGSLIYNGLADFGGQQFKQDLTLKMS-----LEEEISTHDREPAEEEVRAVMAICSSCHTEPFQGAIVFSWKDVREHMNNALKGLSVGPCGNF", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8N7UVM2-1", "uniprot_id": "A0A8N7UVM2_DANRE", "id": "A0A8N7UVM2-1", "name": "", "aln": "MRSPISLRKTALFFLVCFFSACSGTGIPGSDYNPHPRFICTPIPADADPGCFPSAGGPSAGHHSGPSSGGSNSWWGISEEAKTTILHLRESLVQQKETILDQRETIRELTAKLNLCEGFNRGVGNHDDHPHRTPTHLAHHAHHAYPTAPE-PGHLAWAPPPDAHHGGHGLELGHYEDAAHHRGKAAVSEKHVTGEIPLLSSTPEQMSRMLETLKERLENLQTRNTSASYSSSLKDLLQRKISALEQQMQHHSSPLTGASHTDHTEHDDGHHDDEDHDHGHHEDGHDERDHGDPHDDSHHSDRHEDGHHDDDHDDGHHDNDDHDAGHHDNGDHDDDHHDNGHHDNEVSEHGFERLLYNPQGHRESQTGAHSKLDAVLNQLQHRLTEGPRKKTKSTEAFQIGFPMRTNYMYGRVKRTLLHEIFSFTLCLWMKAGIGPGLGTPFSYSVPGQANELVLIEWGNNPMELLVDDKAVTLPLSLSDGKWHHVCVTWSTRDGLWEAYQDGVKRGSGENLSPWHPIKPGGVFILGQEQDTLGGRFDATQAFVGEISDVQMWSQVLTPHDVYSLASCGGHMTGDIIAWSEATVELHGGVTKYPFDPCH--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : * ..:.:* . * . . : *.. *. .* : ..*.*...* :. *. *.: . .:.:.*: : :*:: :: :: :.:.: :: .:. . . . **. .* : ::*: :..:*. **.:: . * .: :*: **: . : .* :: . : *:* : : : * .*: : ** .. ... : ...: .....:. . ..: . ..* .: .. *.: : :: . . .*:*: .*. .*.*: :: . : : *. :* . : . : .::: .*:: * . : :. . * * : :: .::: :. * : :* *..* . . .* .:.: ::. . * ::*:. . : :. . . ::* . . .. :*** *:. .* . ** : : .:. : :. . .:* : : * . . . :::*.:. .::..:. ...** ", "identical_positions": 65, "similar_positions": 232, "identity": "10.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-103", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P31042-1", "uniprot_id": "CD28_RAT", "id": "P31042-1", "name": "T-cell-specific surface glycoprotein CD28", "aln": "---MTLRLLFLALSFFSVQVTENKILVKQSPLLVVDNNEVSLSCRYSYNLLAKEFRASLYKGVNSDVEVCVGNGNFTYQPQFRPNVGFNCDGNFDN-ETVTFRLWNLDVNHTDIYFCKIEVMYPPPYLDNEKSNGTIIHIKEKHLCHAQTSPK-LFWPLVVVAGVLLCYGLLVTVTLCIIWTNSRRNRLLQSDYMNMTPRRLGPTRK--HYQPYAPARDFAAYRP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P31041-1", "uniprot_id": "CD28_MOUSE", "id": "P31041-1", "name": "T-cell-specific surface glycoprotein CD28", "aln": "---MTLRLLFLALNFFSVQVTENKILVKQSPLLVVDSNEVSLSCRYSYNLLAKEFRASLYKGVNSDVEVCVGNGNFTYQPQFRSNAEFNCDGDFDN-ETVTFRLWNLHVNHTDIYFCKIEFMYPPPYLDNERSNGTIIHIKEKHLCHTQSSPK-LFWALVVVAGVLFCYGLLVTVALCVIWTNSRRNRLLQSDYMNMTPRRPGLTRK--PYQPYAPARDFAAYRP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1QVE3-1", "uniprot_id": "A0A8M1QVE3_DANRE", "id": "A0A8M1QVE3-1", "name": "", "aln": "MEIFWRCVTLLSLCLLQSTPSETQNTCKGELPLIEYVPLNSTVKVACPKLSAPEMDFRLFKDGDEVISIYVKIN-HTSIPKTNTNKEFPAEFSVDLDNSSSFILTVVTVNMTALYTCEASISYPPPFKYVDHKPQTIVFVEARSEKRPDLCQQSNHLNLWVAFGLLATYGVLMTCITILRIKPRQIGFFKDRECGRKWQGVQHPTRQGFYIQPRNCLTTSTVTKPL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :*:* ::. :*.: * . *: * . :* * *: *:*. :. :.: * . .* *: ..* * .: ..* :: :* * : ** * :* *: .. ****: ::. **:.:: : :.: . : . * *. *:* **:*:* : . : . : : : . **: ** :. :* ", "identical_positions": 43, "similar_positions": 70, "identity": "19.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-109", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97557-1", "uniprot_id": "KCNV1_RAT", "id": "P97557-1", "name": "Potassium voltage-gated channel subfamily V member 1", "aln": "MDLSPRNRPLLDSSSLDSGSLTSLDSSVFCSEGEGEPLALGDCLTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRLGALAAAPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTDDQESQHESEQDFSQGPCPTVRQKLWDILEKPGSSTAARIFGVISIIFVAVSIVNMALMSAELSWLNL-QLLEILEYVCISWFTGEFILRFLCVKDRCHFLRKVPNIIDLLAILPFYITLLVESLSGSHTTQELENVGRLVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTIEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDS-YISVNLRDIYARSIMEMLRLKGRERASTRSSGGDDFWF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BZN2-1", "uniprot_id": "KCNV1_MOUSE", "id": "Q8BZN2-1", "name": "Potassium voltage-gated channel subfamily V member 1", "aln": "MDLSPRNRPLLDSSSLDSGSLTSLDSSVFCSEGEGEPLALGDCFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRLGALAAAPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTDDQESQHESEQDFSKGPCPTVRQKLWDILEKPGSSTAARIFGVISIIFVAVSIVNMALMSAELSWLNL-QLLEILEYVCISWFTGEFVLRFLCVKDRCHFLRKVPNIIDLLAILPFYITLLVESLSGSHTTQELENVGRLVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTIEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDS-YISVNLRDVYARSIMEMLRLKGRERASTRSSGGDDFWF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PIU1-1", "uniprot_id": "KCNV1_HUMAN", "id": "Q6PIU1-1", "name": "Potassium voltage-gated channel subfamily V member 1", "aln": "--MPSSGRALLDSP-LDSGSLTSLDSSVFCSEGEGEPLALGDCFTVNVGGSRFVLSQQALSCFPHTRLGKLAVVVASYRRPGALAAVPSPLELCDDANPVDNEYFFDRSSQAFRYVLHYYRTGRLHVMEQLCALSFLQEIQYWGIDELSIDSCCRDRYFRRKELSETLDFKKDTEDQESQHESEQDFSQGPCPTVRQKLWNILEKPGSSTAARIFGVISIIFVVVSIINMALMSAELSWLDL-QLLEILEYVCISWFTGEFVLRFLCVRDRCRFLRKVPNIIDLLAILPFYITLLVESLSGSQTTQELENVGRIVQVLRLLRALRMLKLGRHSTGLRSLGMTITQCYEEVGLLLLFLSVGISIFSTVEYFAEQSIPDTTFTSVPCAWWWATTSMTTVGYGDIRPDTTTGKIVAFMCILSGILVLALPIAIINDRFSACYFTLKLKEAAVRQREALKKLTKNIATDS-YISVNLRDVYARSIMEMLRLKGRERASTRSSGGDDFWF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UV51-1", "uniprot_id": "A0A8N7UV51_DANRE", "id": "A0A8N7UV51-1", "name": "Potassium voltage-gated channel subfamily V member 1", "aln": "---MITDSSSPAEFYEDNASLLSLDSSVFFSEPALPTDDPLEFFIINVGGSRYILSQELLASHPETRLGKL-----------ALSSRDSALDLCDDADFLENEYFFDRNSQTFQYIMNFYKTGHLHVREELCVISFLQEIEYWGIDELRIDSCCRDKYYRRKEMKESLDIRKDADVMD---KEEEDFTGVLCQDLRQRLWDIMENPDSSKAAKTFGTLSMFFVVVSIVNMALISLDFSVIGAPIILDILEYICIIWFTGELVLRFLCVRDKCKFSRSVVNIIDLLAILPFYVTLAVESLHG--ESTELENVGRVVQVLRLMRSLRMLKLGRHSTGLKSLGLTIAQCYEEVGLLMLFLSVGISIFATLEYAIEHDTPETTFTNVPSAWWWATTSMTTVGYGDIRPDTAVGKVMAFICILSGILILALPIAIINDRFSACYFTLKMKEAALRHGEVLKRLTRSSASDMSAIGVNLRDVYARSVLEMLRLQGRERASTRSSAGDLWW-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . *..** ******* ** . : : :******::***: *:..*.****** **:: *.*:*****: ::*******.**:*:*::::*:**:*** *:**.:******:******* *******:*:****:.*:**::**:: : :.*:**: * :**:**:*:*:*.**.**: **.:*::**.***:****:* ::* :. :*:****:** *****::******:*:*:* *.* ************:** **** * : *******:******:*:*************:***:**:*********:**********:*:** *:. *:****.**.*********************:.**::**:*******:********************:****:*: *.**:**:. *:* *.*****:****::*****:**********.** :* ", "identical_positions": 313, "similar_positions": 115, "identity": "61.98%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-116", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RZ42-1", "uniprot_id": "ALKL2_RAT", "id": "B2RZ42-1", "name": "ALK and LTK ligand 2", "aln": "MRVSGRP-MLLALLLLLSTVG-DPGHAQPRGPADRQTLLRLLVELVQELKKFHIGDSKRLQLLGESDFALGRREATDYGADQEEQRVEIVPRDLRMKDKFLKHLTGPLYFSPKCSKHFHRLYHNTRDCTIPAYYKRCARLLTRLAVSPMCMER--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80UG6-1", "uniprot_id": "ALKL2_MOUSE", "id": "Q80UG6-1", "name": "ALK and LTK ligand 2", "aln": "MRVSGRP-MLLALLLLLSTVG-DRGRAQSRGPADRQTLLRLLVELVQELKKFHIGDSKRLQLLGESDFALGRREATDYGADQEEQRVEIVPRDLRMKDKFLKHLTGPLYFSPKCSKHFHRLYHNTRDCTIPAYYKRCARLLTRLAVSPMCMER--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UX46-1", "uniprot_id": "ALKL2_HUMAN", "id": "Q6UX46-1", "name": "ALK and LTK ligand 2", "aln": "MRGPGHP-LLLGLLLVLGAAGRGRGGAEPREPADGQALLRLVVELVQELRKHHSAEHKGLQLLG-RDCALGRAEAAGLGPSPE-QRVEIVPRDLRMKDKFLKHLTGPLYFSPKCSKHFHRLYHNTRDCTIPAYYKRCARLLTRLAVSPVCMEDKQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A9Z6-1", "uniprot_id": "A0AB13A9Z6_DANRE", "id": "A0AB13A9Z6-1", "name": "", "aln": "MRALRAPVLVMGLVLLICTAAQSDASAN-----KVEKTLRRIMEIMRQVENSADDES-----AQKTESAPEPKDTHHLKTASGETILEIFPRDLSRKEKFITILTGPLYFGPKCKKDVYRLYHNTRDCTIPAHYKRCARLLTRLAGTRKCQEG--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * :::.*:*:: :.. . . *: . : ** ::*:::::.: : : * :: . :**.**** *:**:. *******.***.*..:*************:************ : * * ", "identical_positions": 57, "similar_positions": 41, "identity": "36.77%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-117", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7Z5L7-1", "uniprot_id": "PODN_HUMAN", "id": "Q7Z5L7-1", "name": "Podocan", "aln": "-MAQSRV-LLLLLLLPPQLHLGPVLAVRAPGFGRSGGHSLSPEENEFAEEE--PVLVLSPEEPGPGPAAVSCPRDCACSQEGVVDCGGIDLREFPGDLPEHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTLAPRFLPNALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGNLEFGDISKDRGRLGKEKEEEEEEEE-EEEETR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TQ62-1", "uniprot_id": "PODN_MOUSE", "id": "Q7TQ62-1", "name": "Podocan", "aln": "-MAGSRG-LPLLLLVL-QLFLGPVLPVRAPVFGRSDTPTLSPEENEFVEEENQPVLVLSSEEPEPGPATVDCPRDCACSQEGVVDCGGIDLREFPGDLPEHTNHLSLQNNQLEKIYPEELSRLQRLETLNLQNNRLTSRGLPEEAFEHLTSLNYLYLANNKLTLAPRFLPNALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDHMFNGSSNVEILILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSNLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIQSVEADVLTPIRNLEYLLLHSNQLQAKGIHPLAFQGLKKLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQMHRDAFRKLRLLRSLDLSGNRLQTLPPGLPKNVHVLKVKRNELAALARGALAGMAQLRELYLTGNRLRSRALGPRAWVDLAGLQLLDIAGNQLTEVPEGLPPSLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVESAFRRLKHLQVLDIEGNFEFGNGSKDKD---EEEEEEEEEED-EEEETR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PQX2-1", "uniprot_id": "A0A8M9PQX2_DANRE", "id": "A0A8M9PQX2-1", "name": "", "aln": "-MDERCG-LLELMCLL---LLGWTLIVRG----------QTETDLHLLDEE-------EAEEVKNAEEKVSCPEKCSCSGEGAVDCNGVSLSEFPQDLSEQTRQLSLQNNQISEVTLEHLSRLQQLETLNLQNNRLTTQGLEDEGFDILERLSYLYLANNKLTAAPRHLPPSLVSADFAANQLTKIFPNTFGQKPALKSVYLHNNKLTDAGLPESMFNGSDSLEILIMSSNFLRYVPKYLPTALYRLHLKNNKLEKIPSGAFDNLFHLRELYLQNNFLSNDGMDNETFSHLNSLEYLDLSNNNLSTVPLGLPRNVILLHLEKNSIQSIAVNALSPIRNLEYLLLHNNRLRSRSIHPAAFQGLKRLHTVHMYNNLLERVPRGLPRRAKTLMLLHNLISEIGRNDLITLYTLTELNLSYNRLTSAKLHREAFRKLRILETLDLSGNKLQALPLGLPKSLQILKVKDNQMTEIPEGALLGMTSLRELYLTNNQLKLSSIYQGAWLEMNALKTLDLSGNMLSHIPPDLPESLEFLHLQNNRINSISETAFLNTPNIKGIFLRFNRLSVNSVSEETFAHLSKLRVLDIG----HGNISPNRGQAGDNMEEEEEELTQEEEETQP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZY32-1", "uniprot_id": "D3ZY32_RAT", "id": "D3ZY32-1", "name": "", "aln": "MLDKSLGRGTAGLTMRPQELLLLLLLLRWP--------AAHTEDPAFPHLG-------DSSQPLPR----PCPWRCSCPRDDTVDCAGLDLRVFPDNITRAARHLSLQKNQLQELPYNELSRLSGLRTLDLHSNLISSEGLPDEAFESLTQLENFYVAHNKLSVAPQFLPRSLRVADLAANEVVEIFPLTFGEKPALRSVYLHNNRLRNTGLPPNTFHGSEAITTLSLSSNQLRYLPPSLPASLERLHLQNNLISKVPRGALSLQTQLRELYLQHNQLTDSGLDATTFSKLSSLEYLDLSHNQLATVPEGLPGNLTILHLGRNCIRHVEAIRLHKAKGLRYLLLQHNKLEASALPAGTLRPLRALHTLHLYGNRLERVPPALPRHLQALVMPHNRVAALGARDLVSARALTELNLAYNRLASAHVHPGAFRRLRALRSLDLAGNQLSRLPEGLPASLRSLRLQRNQLRTLEPEQLAGLNKLRELNLAHNRLRVGDIEPGAWHELQALQVLDLSHNELSFVPPDLPEALEELYLQANRISHVGPEAFLSTPHLRALSLRANRLHMTSIAAEAFRGLAHLRVVDTA----------------ENLEQVLIQLPRKGKEP--", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : * * :* : : . ...: ** *:*. :..*** *:.* ** ::.. :.:****:**:.:: :.**** *.**:*:.* :::.** ::.*: * *. :*:*:***: **:.** :* .*:*** :.:*: ***:** *:*******:* ::*** *:**. : * :*** **::* **.:* :***:** :.*:* **:. *******:* *::.*:* ** :*.******** *:*: ** *** .: :*** :*.*: : . * :.*.****: *:*. .: . ::: *: ***:*:*.* ***** .***: ::*:: ** :: :* .*: : * ****:***::*.::* ***:** *.:***:**:* ** *** .:: *::: *:: : * *: .**** *: *:*: : ** :: *: **:: * *: :* .** :** *:** *:*. : ** .**:::.: ** *:* : *: .:* * :*:*:* .: *: : : :*. ", "identical_positions": 221, "similar_positions": 183, "identity": "35.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-12", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q568Z1-1", "uniprot_id": "F131B_RAT", "id": "Q568Z1-1", "name": "Protein FAM131B", "aln": "---MDS-TSSLHGSSLHRPSTEQTRTDFSWDGINLSMEDTTSILPKLK-RNSNAYGIGALAKSSFSGIS---RSMKDHVTKPTAMGQGRVAHMIEWQGWGKAPA---------IQPQHSHEAVRRDTDAYSDLSDGEKEARFLAGVMEQFAISEATLMAWSSMDGEDMSVNSTQEPLDCNYSDNYQELMESQDALAQAPMDGWPHSYVSQGMYCLGSSDAWEAS--DQSLIASPATGSYLGPAFD----DSQPSLHDMGPSQPASGYS---------------------------------------AQEPPP-----------------LLGVDTDWASEVGGVELARGPVE-----------EEKRPLAPEE-------EEDAGCRDLESL----SPREDPEMSTALS--------------RKVSDVTSSGVQSFDEEEGDANN--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TY60-1", "uniprot_id": "F131B_MOUSE", "id": "Q3TY60-1", "name": "Protein FAM131B", "aln": "---MDS-TSSLHGSSLHRPSTEQTRTDFSWDGINLSMEDTTSILPKLK-RNSNAYGIGALAKSSFSGIS---RSMKDHVTKPTAMGQGRVAHMIEWQGWGKAPT---------IQPQHSHEAVRRDTDAYSDLSDGEKEARFLAGVMEQFAISEATLMAWSSMDGEDMSVNSTQEPLDCNYSDNYQELMESQDALAQAPMDGWPHSYVSQGMYCLGSSDAWEAS--DQSLIASPATGSYLGPAFD----DSQPSLHDMGPSQPASGYS---------------------------------------AQEPPP-----------------LLGVDTDWASEVGGVELARGPVE-----------EEKRPLAPEE-------EEDAGCRDLESL----SPREDPEMSTALS--------------RKVSDVTSSGVQSFDEEEGDANN--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86XD5-1", "uniprot_id": "F131B_HUMAN", "id": "Q86XD5-1", "name": "Protein FAM131B", "aln": "---MDS-TSSLHGSSLHRPSTEQTRTDFSWDGINLSMEDTTSILPKLK-RNSNAYGIGALAKSSFSGIS---RSMKDHVTKPTAMGQGRVAHMIEWQGWGKTPA---------VQPQHSHESVRRDTDAYSDLSDGEKEARFLAGVMEQFAISEATLMAWSSMDGEDMSVNSTQEPLGCNYSDNYQELMDSQDALAQAPMDGWPHSYVSQGMYCLGSSDAWEAS--DQSLIASPATGSYLGPAFD----DSQPSLHEMGPSQPASGYS---------------------------------------ALEPPP-----------------LLGGDTDWAPGVGAVDLARGPAE-----------EEKRPLAPEE-------EEDAGCRDLESL----SPREDPEMSTALS--------------RKVSDVTSSGVQSFDEEEGEANN--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ATB3-1", "uniprot_id": "A0A8M3ATB3_DANRE", "id": "A0A8M3ATB3-1", "name": "", "aln": "MGCIGSRTLTSDGVPVQKDGEQHGRTDFSWDGINLSMEDTTSILPRLKKRNSNAYGIGALAKSSLTGVSGVSRSMKDKVTKPTAMAQGRVAHMIEWQSWGMQTVGVGGRGAGRTSSLHLQQERKLENDAYSDLSDGEKEARFAAGVLQQFAISEATLLAWSSMDGESTSIGSNQGSVAH-LSEANQESITSRDQMHHSSAEVWPHNYVSQGLYCLSSSDAWEPISNEQSGVASPATGSYVMAVGNEGGYDPNTATHFLSQQQQQHQYQNQLQQIQHLQHIHQYQQQQLLQYQQQQQILEQRLQSATHSLQATPNSTIHSLPPLTHPPLVDLWGTPQTEVYQPDTVGYMGMPVDGNLTVPTEDVITEHSSLLDDEQDGEIKVEEVTLCMEPEAVTLIPSPVAQKEEVTSAGGSSPGQSSGEFITERKTSDVSPSVIEELEEKEESESSPTDTKATN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.* * : .* .::: . :: *********************:** ***************::*:* *****:*******.***********.** .. .. * :: : :.*************** ***::*********:********. *:.*.* .: *: ** : *:* : ::. : ***.*****:***.******. :** :********: .. : *.:.: * :. .* *. : :..* * * . . * *.: *: .* :* ** : * : *:: ** : * *: . **.***:.* ::.::*:* . .. ", "identical_positions": 167, "similar_positions": 92, "identity": "36.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-122", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NQP4-1", "uniprot_id": "PFD4_HUMAN", "id": "Q9NQP4-1", "name": "Prefoldin subunit 4", "aln": "MAATMKK-AAAEDVNVTFEDQQKINKFARNTSRITELKEEIEVKKKQLQNLEDACDDIMLADDDCLMIPYQIGDVFISHSQEETQEMLEEAKKNLQEEIDALESRVESIQRVLADLKVQLYAKFGSNINLEADES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R0Z8-1", "uniprot_id": "F1R0Z8_DANRE", "id": "F1R0Z8-1", "name": "Prefoldin subunit 4", "aln": "MAATMKKGVAAEDVNVTFEDQQKINKFARNTNRMSELKDEIEAKKKSLQNLEDASDDLMMCEDDSMLIPYQIGDVFISHSQEETQEMLEAAKEALQEEIKALEGRVSSIQGVLGDLKVQLYAKFGNNINLEADES", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******* .**********************.*::***:***.***.*******.**:*:.:**.::********************** **: *****.***.**.*** **.***********.*********", "identical_positions": 110, "similar_positions": 21, "identity": "81.48%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-124", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A6R6-1", "uniprot_id": "D4A6R6_RAT", "id": "D4A6R6-1", "name": "", "aln": "-------------RMSQEPRMYSLLLVLFLSHGGACQREPSSRQDLHPLLQKMAEEIIEGSYLNALLDLALFESSHVWTADLSHRVLAYLNSRNVAFTIPSLQAVMETHLEQYLYQ--PQKLLEDLRATDAQQFHT----AMKCLLEDKWGHLDLEDIVINLGDIRDEALQSPGVNRSLFLITLER-----------------------CFQVLNALECVEVLGKVLRGSSGSFLQPDITDRLPQDLHEDAFKNLSAVFKDLYDQTSAHTQRALYSWMTGILRTPFNVTDGSISWVSAEKLWILGRYMVHLSFEEIMNISPIEIGLFISYDNATKQLDMVYDVTPELAQAFLERIRGSSFDMRNIST-IHR--------------LGLLVCFYDGLELLDAALAQVLLHQMLKCSRLRGFQAGVQKLKANLLD--IATENQTLNETLGSLSDAVVGLTSTQLESLSSDAVHSAISTLNQVTGWGRSQIVILSAKYLAQEKVLSFYSVSQMGVLLAGVGTQAFYSMDHKDLWQVLRSPLSQDMSDLSPVQHQGVLSKLMEAEDAASGIVEVPRALFKEVSLYDLWKGPGFNATVLKEKELRRSQALFLYELLEKTTERPEELLSSRQLVKGVQCSHIDAMSAHVFLALFQHFENNFSLLSPDQVNCLAWKYWEVSRSS---------------MPPFLLATLPSRFLASVPPSRCVRFLISLGKRHLDTLVLDSDKRSLVIRKVQQCLDGVIADEYTVDIVGN--LLCHLPASFIERGISPRAWATALHGLRSCRALSSGQKAAVRFRLLEQWGPPQNWTAETTKDLAPFLAFFSGDELHTVATKFPEILQQTASKMVG---TLLPKEF-LWAVFESVRNSSNESPGSDPTFGCHG------VVTPSSDDIVKLAEANACWDPEVLLCMEEDTFIRNVELLGAVKGFSRPQLMALKEKAIQVWDLPSHWKEHHVVSLGRIALALNESELEQLDLSSIDTVASLGQQTEWTPGQAKSILQEFLEDSGCGIQDLKSFHLVGLGPTLCAMDPTEIPLIKTSEFRAVVARIGTLLCSTPVLAGFKKKAEVVFGRPTEWTSSILQELGTIAAGLTKAELRMLDKELMPYFQPWAIRCLPGEVFKELSTEQIASLGPQNAAFVTHSQRLQLSSSQLQSLQRAVDGAKTHFWQIDPMSSSPTWPASTGSPTGEPTFQALWLGCPLLLLMAKS---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K561-1", "uniprot_id": "OTOAN_MOUSE", "id": "Q8K561-1", "name": "Otoancorin", "aln": "--------------MSQGPRTCSLLLVLLLSHGGAYQREPSPRQDLHPLLQKMAEEIIEGSYLNALLDLTLFERSHVWTADLSHRVLAYLNSKNVAFTIPSLQAVMEAHLEQYLYQ--PQKLLEDLRATDNQQFHT----AMKCLLEDKWGHLDLEDVVINLGDIRDEALQSPGVNRSLFLITLER-----------------------CFQVLNALECVEVLGRVLRGSSGSFLQPDITERLPQDLHEDAFKNLSAVFKDLYDQTSAHTQRALYSWMTGILRTPFNVTDGSVSWVSAEKLWILGRYMVHLSFEEIMNISPIEIGLFISYDNATKQLDMVYDITPELAQAFLERIRCSSFDVRNIST-IHR--------------LGLLVCFYDGLELLDATLAQVLLHQMLKCSRLRGFQAGVQKLKANLLD--IATENQTLNETLGSLSDAVVGLTSSQLESLSSDAVHSAISTLNQVTGWGRSQIVILSAKYLAQEKVLSFYNVCQMGVLLAGVGTQAFYSMDHKDLWQVLRSPLSQDMSDLSPVQQQGVLGKLMEAEDATSGIAEVPRALFKEVSLYDLWKESRFNATVLKAKELRRSQALFLYEFLGKTTERPEELLSAGQLVKGVPCSHIDAMSDHLFLALFQYFDNNFSLLSPDQVNCLAWKYWEVSRSS---------------MPPFLLATLPSRFLSSIPPSRCVRFLISLGKRRLETLVLDSDKRSVVVRKVQQCLDGVIADEYTVDIVGH--LLCHLPASFIERGISPRAWAAALHGLRSCTALSSEQKAAVRVRLLEQWGPPENWTAETTKDLAPFLAFFSGDELHTVATKFPEILQQTASKMVG---VLLPKEF-LWAVFESVQNSSNESPSFDPTFGCHG------VVTPSSDDIFKLAEANACWDPEVLLCMEEDTFIRNVELLGAVKGFSRAQLMALKEKAIQVWDLPSRWKEHHIVSLGRIALALSESELEQLDLSSIDTVASLGQQTEWTPGQAKSILQAFLEDSGYGIQDLKSFHLVGFGPTLCAMDPTEIQLIKTSEFRAVVARIGTLFCSTPVLAGFKKKAEVVFGRPTEWTSSILQELGTIAAGITKAELRMLNKELMTYFQPSAIRCLPGEVFKELSTEQIASLGPQNAASVTHSQRLQLSSAQLQSLQRALDGAKTHSWQTDPLSSSPTWPASTGSPTGEPASQALWLGCTLLLLTAKS---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7RTW8-1", "uniprot_id": "OTOAN_HUMAN", "id": "Q7RTW8-1", "name": "Otoancorin", "aln": "--------------MSQEPTTYSLFLFLFLSHGVSSYTVPNSRQDLHPLLQNMAEEIIDGSYLNALLDLIQFQSSHVWTDDLSHRVLAYLNSRNVAFTIPSLQAAVENHLEQRLHQ--PQKLLEDLRKTDAQQFRT----AMKCLLEDKKDGLDLKDIIIDLGEIRERALQSPGVNRSLFLITLER-----------------------CFQMLNSLECVEILGKVLRGSSGSFLQPDITERLPRDLREDAFKNLSAVFKDLYDKTSAHSQRALYSWMTGILQTSSNATDDSASWVSAEHLWVLGRYMVHLSFEEITKISPIEIGLFISYDNATKQLDMVYDITPELAQAFLERISSSNFNMRNTST-IHRQAHELWALEPFPKMLGLLVCFYNDLELLDATVAQVLLYQMIKCSHLRGFQAGVQKLKAELLD--IAMENQTLNETLGSLSDAVVGLTYSQLESLSPEAVHGAISTLNQVSGWAKSQVIILSAKYLAHEKVLSFYNVSQMGALLAGVSTQAFCSMKRKDISQVLRSAVSQYVSDLSPAQQQGILSKMVQAEDTAPGIVEIQGAFFKEVSLFDLRRQPGFNSTVLKDKELGRSQALFLYELLLKTTRRPEELLSAGQLVKGVTCSHIDAMSTDFFLAHFQDFQNNFALLSPYQVNCLAWKYWEVSRLS---------------MPPFLLAALPARYLASVPASQCVPFLISLGKSWLDSLVLDSHKKTSVLRKVQQCLDDSIADEYTVDIMGN--LLCHLPAAIIDRGISPRAWATALHGLRDCPDLNPEQKAAVRLKLLGQYGLPQHWTAETTKDLGPFLVLFSGDELSSIATKFPEILLQAASKMAR---TLPTKEF-LWAVFQSVRNSSDKIPSYDPMPGCHG------VVAPSSDDIFKLAEANACWALEDLRCMEEDTFIRTVELLGAVQGFSRPQLMTLKEKAIQVWDMPSYWREHHIVSLGRIALALNESELEQLDLSSIDTVASLSWQTEWTPGQAESILQGYLDDSGYSIQDLKSFHLVGLGATLCAINITEIPLIKISEFRVVVARIGTLLCSTHVLAEFKRKAEVVFGDPTEWTSSVLQELGTIAAGLTKAELRMLDKDLMPYFQPSAIKCLPDEIFKELSAEQIASLGPENAAAVTHAQRRRLSPLQLQSLQQALDGAKTHSWQDAPASAGPTRTSSSRSPAGALQSWGLWLGCPLLVLMAKLLW-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXK7-1", "uniprot_id": "E7EXK7_DANRE", "id": "E7EXK7-1", "name": "", "aln": "MGFYREVFILSLLVQLAAVMSQDMVASQMLNSNQSTIGFPRLPADFREMAKKLMITCSNKGYQMPAMNHTQNSSHAQMMESPVPVFLELLSSIPPFSHARPYMKPNDTAEEQEITRNFAEKMRNCTNMGHMIEFMRNATEGPRCFMRAFVAPLSWTIIMQNGTDLLKEDLTKLLWAAKPFLETMPPSSFVLPPFTQNSQLAEMMKVFSEVFAVLSEQQKNEIIGWVKERNAQNEFNCHLKAPTTNNSQQEKPASQSDPSVKMLDMMSKPSDEVAKPSVMNVSTPVHTVCPAKMLWLKAKMLSMMGPFLSSLPIEEVKNIPKEELCDFFRTPDFPPSFQNVTGMKPVLGRTLFQRLKQECSSSDNFTQNVYR--------------LGSLACFFDSAPSLNLTLSRKLLSQIEACSNQE-----VDKVKRQLVQNILEKDDSSSSELLQSLGSSVSALPVSRLSRFSPEDLNSTLSTLSQVK-WSPAQATALAKKMLETAKNVSGEKLLSLGSVVRGVASSLLKNVKTEGLLENK--ALENMAEKMSSLQRTALLNAFRRDVNASELVKGLPDSLLSSLSLSILEKADLGSVDQLKGRGWTRAQSVFLLKKIMGNKINLGELGKLGQAVQGVTCEMLEKFNRTDALQMSQELNKSYIWLSRTQIRCAAQKLFASLEAQRAGYFNDIKNAELQAIPAVLLINLPVEKIQNLSDAVCPAFMEKMKDVNLSSLPNSSPARSALTKRAIGCLKGNLSDLTAAEVLTLGPLVCELDPVWISS-LNPAARNATLKSLASCQYIQQQNRQDLFRLLNAIYGDPAYWSEEDVRAIGPLLFLNDTAVEKLPSKSWLKLYLSELDSLSSQPAVPPPKEFSTWFDLSALRRKLFELKTTSALLSRRKRAVVLTTTDLTLANIEDLKQGNVYWTAAQFSKMAVQIFKDAMPTLGEINNYSTEQLTALKAKTVEAWGSVSMLNESLISNLGCICQSFSAEELGNLSIASLDTLEILAN-CNFTQTQRAAIWQAFQRTTGMNVFGLGELETAGLGQFICGLQPAQIDLLNPLSFREAVEAVGRTSCPPNILDRLKEKTVAVFGKPENWTEAQICIMGNIIAGLNAVEMSRLNPTILPFIQPSAIPLIPGDRLAMLSVSQLKALGPDNAAMVTDAQRVGLKVDQRAALDEAVG-LKTARADVPTGTSTGNSTGNSNPSSGGSGAQPLKGGATVESMAGSVLLVQVIVLVLIGYIF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:. :*. . : * *:: : ::: : .* . :: . . .* *.* . : ** : : .:*: : . . :* . :*::. *. :: : :: .. * . . ** *: * :*. : *::* * . .: . :: .:. ..: ::: . * .: * * ::.. . : .: . .. . *:.*: * ::* :: *.:**: :*. *: *: : . .:: * .:.* *.:::::*: . . * : ::* ** *.**::. *: :::: ** *: **. . *:*:* :*:: : ::.: .* * **..:* .*. ::*. :*.: ::.::***.**. *. :* *: * * * :* .: .:* :: **.:. : .:. :.: : .:.: ..:*. *: .:*. : . ::: : : :::..:** * : . ** : *:*::** : : .. . ** . * *:** *. :: :. * * :::.: ** *:.* * * : . . :*..** ** . : .:. : * *: .: . *.:* .* :: : ::. **.. ::* :.::: *:*.* . *. :.* * ::*:.* .* :. :: : * :* * *: * .: :.*:* : . :..: :: . ..: . .*** * :.:::.. : .. . : .. : :* .* :.*. * : * : * : ** ::.:* ** :** *:::.*. * .* : .** *. ::. .** :*.::*:**: *. ::* * :* * : :* .: .* .:. .*:* :*.:: ::* *:: .** .* :* *.. :* :*.*: .*** * :**.: : :*.* **:. .*: *: ::.::** ** :*.: : **..*: :***:*** **.:** *. * :*:.*:. ** : . :: . ...: ..:* * *..: : .. ", "identical_positions": 224, "similar_positions": 431, "identity": "18.08%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-125", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D572-1", "uniprot_id": "UBX11_MOUSE", "id": "Q9D572-1", "name": "UBX domain-containing protein 11", "aln": "MSSPLASLSKTRKVPLESESVNPGRRGIRVYGNED-EVDMWNDGQDSEEKIS-LPSCYGGIGAPVSR----QGP--HDSELMASMTRKLQELEQQLQAQNDEMLSKERKILDLEDLVQTLQQHQNNAALQ----RQEELETQCIQLQRQIGEMERFLSDYGLQWVGEPMDQENSEEKTVSENDERDWMKAKKFWKPGDSFVPPEVDFDKLMASLQDLSEL-VEGEAQVTPVPGGARFRTLEPIPLKVYRNGIMMFDGPFRPFYDPSTQRCLRDILDGFFPSELQRLYPDGVPFKVSDLRNQIYPEDG-LGQFPGEGRVVG-------RQKMRKVTDRVEETSGSRMTAEQFLNRLPKCIIRQGEVIDIRGPIRDTLQNCCPMPARIQEIIVETPALASERQRSQESPDMPMPLLSMLRIKSENGEQAFLLMMWPEDTIGDVRKLLAQARDMDSAAFEILSTFPPTVYQDDTVTLQAAGLVPNATLLLRTRRALLSNPISRPGSLP---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T124-1", "uniprot_id": "UBX11_HUMAN", "id": "Q5T124-1", "name": "UBX domain-containing protein 11", "aln": "MSSPLASLSKTRKVPLPSEPMNPGRRGIRIYGDED-EVDMLSDGCGSEEKIS-VPSCYGGIGAPVSR----QVPASHDSELMAFMTRKLWDLEQQVKAQTDEILSKDQKIAALEDLVQTLRPHPAEATLQ----RQEELETMCVQLQRQVREMERFLSDYGLQWVGEPMDQEDSESKTVSEHGERDWMTAKKFWKPGDSLAPPEVDFDRLLASLQDLSELVVEGDTQVTPVPGGARLRTLEPIPLKLYRNGIMMFDGPFQPFYDPSTQRCLRDILDGFFPSELQRLYPNGVPFKVSDLRNQVYLEDG-LDPFPGEGRVVG-------RQLMHKALDRVEEHPGSRMTAEKFLNRLPKFVIRQGEVIDIRGPIRDTLQNCCPLPARIQEIVVETPTLAAERERSQESPNTPAPPLSMLRIKSENGEQAFLLMMQPDNTIGDVRALLAQARVMDASAFEIFSTFPPTLYQDDTLTLQAAGLVPKAALLLRARRAPKSSLKFSPGPCPGPGPGPSPGPGPGPSPGPGPGPSPCPGPSPSPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R1A5-1", "uniprot_id": "F1R1A5_DANRE", "id": "F1R1A5-1", "name": "UBX domain-containing protein 11", "aln": "MTSPLSILRKNRRAPLPDLHTDGERKPHKERSDSDYEEKLFQDIFPQNQPVPRVPDHLSTLRSKFMQKKKAKAAVPSDFELMSSMMQKICHLERKVKTQAVDIEQKARRIAVLEEKLNILREAKVLEESASNENQDEGLVQFCLKLQKQVWEMENFLNDYGMIWVGGYEENQDERAESQLTG-------------ASSGRKRFEMNFDLVMQNVKELNLEAGEGESHVTAIPGGAKLTQKPPIPLWLYKNGIVMFNGPFRSYQDPTTQECMQDLMDGFFPSELQERFPNGVPFQVNDRREEEFIVRRPRAEFPGRGQTIDGGQQMMDSSEISSTIPKQSQIAGRKLSMEQFLRKLPETVVKAGKVISIRDSVKAHLLGLSDDAKSRSAIIVETSALQSSRECENDSSKS-AKDVSTLRVKSEDGTDTFIIKMYFTETIGDLRQYLDVKRGPSAASYDIISAFPQRRYSDDTQTLLACGLTPNAALLLRAQAPAHRH------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:***: * *.*:.** . : *: : .:.* * .: .* .:: :. :*. . : : . : : . * ***: * :*: .**:::::* :: .* ::* **: :: *: ::* * *::**:*: ***.**.***: *** ::::.. :: .... *::** :: .:::*. **:::**.:****:: **** :*:***:**:***:.: **:**.*::*::*********. :*:****:*.* *:: : ***.*:.:. . : .. : .: .* ::: *:**.:**: ::: *:**.**..:: * . . . . *:***.:* :.*: .::*.. :* **:***:* ::*:: * :****:* * * .:::::*:*:** *.*** ** *.**.*:*:****:: . ", "identical_positions": 151, "similar_positions": 174, "identity": "28.07%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-13", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC45-1", "uniprot_id": "B1WC45_RAT", "id": "B1WC45-1", "name": "Vacuolar protein sorting-associated protein 72 homolog", "aln": "--------------MSLAGGRAPRKTAGNRLSGLLEAE----EEDEFYQTTYGG------------FTEESGDDEYQGDQSDTEDEVDSD------------------------FDIDEGDEPSSDGEAEEPRR--KRR--VVTKAYKEPLKSLRP----RKVSTPASSSQKAREEKTLLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQ------SRRRKGPHCERPL-TQEELLREAKITEELNLRSLETYERLEADKK-----------------------------------------------KQVHKKRKCPG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PIITYHSVTVPLVGEPGPKEENVDVEGLDP--------------------APTSSALTAHAGTGP-----AVPPPHCSRTFITFS-----------------------------------DDATFEEWFP--------------------------------------------------QGRPPK-----VPVREVCPVTHRPALYRDPVTDIPYATARAFKIIREAYKKYITAHGLPPTASALGPGPPPPEPLPGAGPRALRQKIVIK-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62481-1", "uniprot_id": "VPS72_MOUSE", "id": "Q62481-1", "name": "Vacuolar protein sorting-associated protein 72 homolog", "aln": "--------------MSLAGGRAPRKTAGNRLSGLLEAE----EEDEFYQTTYGG------------FTEESGDDEYQGDQSDTEDEVDSD------------------------FDIDEGDEPSSDGEAEEPRR--KRR--VVTKAYKEPLKSLRP----RKVSTPASSSQKAREEKTLLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQ------SRRRKGPHCERPL-TQEELLREAKITEELNLRSLETYERLEADKK-----------------------------------------------KQVHKKRKCPG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PIITYHSVTVPLVGEPGPKEENVDVEGLDP--------------------APTASALAPHAGTGTGAA-AATPPAHCSRTFITFS-----------------------------------DDATFEEWFP--------------------------------------------------QGRPPK-----VPVREVCPVTHRPALYRDPVTDIPYATARAFKIIREAYKKYITAHGLPPTASALGPGPPPPEPLPGSGPRALRQKIVIK-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15906-1", "uniprot_id": "VPS72_HUMAN", "id": "Q15906-1", "name": "Vacuolar protein sorting-associated protein 72 homolog", "aln": "--------------MSLAGGRAPRKTAGNRLSGLLEAE----EEDEFYQTTYGG------------FTEESGDDEYQGDQSDTEDEVDSD------------------------FDIDEGDEPSSDGEAEEPRR--KRR--VVTKAYKEPLKSLRP----RKVNTPAGSSQKAREEKALLPLELQDDGSDSRKSMRQSTAEHTRQTFLRVQERQGQ------SRRRKGPHCERPL-TQEELLREAKITEELNLRSLETYERLEADKK-----------------------------------------------KQVHKKRKCPG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PIITYHSVTVPLVGEPGPKEENVDIEGLDP--------------------APSVSALTPHAGTGP-----VNPPARCSRTFITFS-----------------------------------DDATFEEWFP--------------------------------------------------QGRPPK-----VPVREVCPVTHRPALYRDPVTDIPYATARAFKIIREAYKKYITAHGLPPTASALGPGPPPPEPLPGSGPRALRQKIVIK-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AJ70-1", "uniprot_id": "A0A8M3AJ70_DANRE", "id": "A0A8M3AJ70-1", "name": "Vacuolar protein sorting-associated protein 72 homolog", "aln": "--------------MSLAFSRAPRKTAGNRMSRLLDAE----EEDEFYKTTYGG------------FHDESGDEEYKGDLTETEDEVDSD------------------------FDIDEGDEPDSEQEEDGPRR--KSR--VVTKAYKEPVKVVRQKPKQRKLAELPRRTDKTKIDK-YNPPELQDDIN--RKSVRQSTTEHTRLTYLRLQERQVA------PRRRKGTRHERPL-TQAELLAEAKVTAEINLRSLENYERLEADKK-----------------------------------------------RQVHMKRQCVG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVIRYHSVLMPLVSDVTLKEENVDVEGLDQDAQQNP----------HLPQALSQSESTLSAAPGVPFTNTAAVNTKCSRTYITFS-----------------------------------DDESFQRVFP--------------------------------------------------QSPAPR-----VPVQEVCPVTHKPALYRDPITDIPYANVQAFRIIREAYKKYVAAHGLP----CTGPSTP-----ADTTAKSLKQKIIIKQAI----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKM6-1", "uniprot_id": "VPS72_DROME", "id": "Q9VKM6-1", "name": "Vacuolar protein sorting-associated protein 72 homolog", "aln": "----------------MAASRSRRNNAGNKIAHLLNEE----EEDDFYKTSYGG------------FQEDEEDKEYE-QKDEEEDVVDSD------------------------FSIDENDEPVSDQEEAPEKK--RKRGVVNTKAYKETKPAVKK---ETKATPALHKKRPGGGVTKRRPRPRFTVLDSGRKSIRTSTAIKTQATKIRLKELDDAR-----KRKKKKVRVEDYMPTQEELLEEAKITEEENTKSLEKFQKMELEKK-----------------------------------------------KSRPTKRTFSG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTIRYHSLTMPAMRKPT-RGANPAVDSKDL-------------------------------------------AGKCERTFVTIENDF--------------------------------NDKVFQSLFR--------------------------------------------------HKAPPK-----ASN-GICPITRLPARYFDPITQQPYYSIQAFKILREAYYMQLEQQGGGSEQPELAKWLEWRKLVKENRLKASAAASKNGDN-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03388-1", "uniprot_id": "VPS72_YEAST", "id": "Q03388-1", "name": "Vacuolar protein sorting-associated protein 72", "aln": "MSDEGADKSLDTNTEFIIQTRSRRSNAGNKLQKLLEQELRDIESTKRQISSYKNGNDDEEDEIGLLFQEDEDDEDFEMMAKDDDDEGEEKEDETQSIRKEPSQASSEQAADDLMFSSSESEDSSNENDEDAEEKEIRRQELLSRKKRNKRLQKGPVVIKKQKPKPKSGEAIPRSHHTHEQLNAETLLLNTRRTSKRSSVMENTMKVYEKLSKAEKKRKIIQERIRKHKEQESQHMLTQEERLRIAKETEKLNILSLDKFKEQEVWKKENRLALQKRQKQKFQPNETILQFLSTAWLMTPAMELEDRKYWQEQLNKRDKKKKKYPRKPKKNLNLGKQDASDDKKRESEESIKNDGDVNSLGENSSSVHNQKRIEETSTNDTVEGESSPDAAVSRVNSDELKPTALPDVTLDAIANKQSTVDEAPNSQPQKNIITNEQKITNVGEPIQNLHNEEIKDEMVSALESRENTFENSSPAAQVVSQRDNSATPTPSNSTGTEDTILISPDTDIKGEPEPCLKTEGIENLSHNVPQETKSNTDVSFLKQVTFTDHPQVAIIDTEESPSKKDTANVDESSAENSLSTQTYEGPEQLTSRNFVTLYDFPNAPPNLKDFNTNLFGDRWSYTNGLSATQRPQDMKTVFHSILPSPPQSSVPSPTVDISLDLSALANFPSFGEYDKKIVHQINTEINKDLEIKIKTQPPTGVFLANGIRKKCLITNKECQYFDPRTGVPYSDVEAYKIIQRIQDPISKEEGRSDIKRDETTNEDSDDQVRFKWFGFKNGGIYLDLSQRPAKGVPEGF", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: *..***:: **: * *. . ::* . * ::. *.::: : :* :.. *. .*.::. .: : .: : : : * :: * . . *.* * *. :* . ::.: : ::: : . : ** * * ** * : * **:.::. * ** : *: . : ..: * :. . .*.::*: . *. : : .* * :*. . * ** * ** .*::*::. .* ", "identical_positions": 52, "similar_positions": 93, "identity": "6.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-133", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q09QM4-1", "uniprot_id": "GPR17_RAT", "id": "Q09QM4-1", "name": "Uracil nucleotide/cysteinyl leukotriene receptor", "aln": "----------------------------MDGLETALPSLTDNASLAYSEQCGQETPLENMLFACFYLLDFILAFVGNALALWLFIWDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIPCRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWIVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALASLAVAFTFPFITTVTCYLLIIRSLRQGPRIEKHLKNKAVRMIAMVLAIFLICFVPYHIHRSVYVLHYRGGGTSCSAQRALALGNRITSCLTSLNGALDPVMYFFVAEKFRHALCNLLCSKRLTGP-PPSFEGK-TNESSLSARSEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6NS65-1", "uniprot_id": "GPR17_MOUSE", "id": "Q6NS65-1", "name": "Uracil nucleotide/cysteinyl leukotriene receptor", "aln": "----------------------------MNGLEAALPSLTDNSSLAYSEQCGQETPLENMLFACFYLLDFILAFVGNALALWLFIWDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIPCRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWIVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALASLAVAFTFPFITTVTCYLLIIRSLRQGPRIEKHLKNKAVRMIAMVLAIFLICFVPYHIHRSVYVLHYRGGGTSCAAQRALALGNRITSCLTSLNGALDPVMYFFVAEKFRHALCNLLCSKRLTGP-PPSFEGK-TNESSLSARSEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13304-1", "uniprot_id": "GPR17_HUMAN", "id": "Q13304-1", "name": "Uracil nucleotide/cysteinyl leukotriene receptor", "aln": "MSKRSWWAGSRKPPREMLKLSGSDSSQSMNGLEVAPPGLITNFSLATAEQCGQETPLENMLFASFYLLDFILALVGNTLALWLFIRDHKSGTPANVFLMHLAVADLSCVLVLPTRLVYHFSGNHWPFGEIACRLTGFLFYLNMYASIYFLTCISADRFLAIVHPVKSLKLRRPLYAHLACAFLWVVVAVAMAPLLVSPQTVQTNHTVVCLQLYREKASHHALVSLAVAFTFPFITTVTCYLLIIRSLRQGLRVEKRLKTKAVRMIAIVLAIFLVCFVPYHVNRSVYVLHYRSHGASCATQRILALANRITSCLTSLNGALDPIMYFFVAEKFRHALCNLLCGKRLKGP-PPSFEGK-TNESSLSAKSEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PYM7-1", "uniprot_id": "A0A8M9PYM7_DANRE", "id": "A0A8M9PYM7-1", "name": "Uracil nucleotide/cysteinyl leukotriene receptor", "aln": "----------------------------MESSLTELPTLLPNQSMDSCPPV--ENTAENMMFGIYYIIVFLLALSGNSLALWIFARQRNNSSPANVFLLHLAVADLFYVFILPLRATYHLTGGHWPFGEIPCRLAGFFFYVNMYASLYFLACVAGDRYLAVVHAVRSLKVRRPHYAHIASFALWILVIVSMAPLLITKQTVEVNGSTVCLQLYREKASWRALVSLVVAFTPPFIATLSCYLLIVNSLRKGSRLEPALKLRALRTIGLVMFIYVVCFLPYHLSRATFILGYGHPDLSCQIKRGLALANRLTSSLTCLNGGLDPLVYLFAAEKFRGSVRRIFCRDKSGGSGATSGELKGTHESSLSAKSEF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:. . * * * *: . *.. ***:*. :*:: *:**: **:****:* :::..:******:******* *::** * .**::*.*******.***:**:**:*****:***:*::.**:**:**.*:***:*** ***:*. **::* *:*****:: ***:.* :.*********** :**.**.**** ***:*::*****:.***:* *:* ** :*:* *.:*: *:::**:***: *:.::* * . ** :* ***.**:**.**.***.***::*:*.***** :: .::* .: *. ..* * * *:******:**:", "identical_positions": 182, "similar_positions": 102, "identity": "49.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-14", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P24473-1", "uniprot_id": "GSTK1_RAT", "id": "P24473-1", "name": "Glutathione S-transferase kappa 1", "aln": "MGPAPRVLELFYDVLSPYSWLGFEVLCRYQHLWNIKLKLRPALLAGIMKDSGNQPPAMVPHKGQYILKEIPLLKQLFQVPMSVPKDFFGEHVKKGTVNAMRFLTAVSMEQPE---MLEKVSRELWMRIWSRDEDITESQNILSAAEKAGMATAQAQHLLNKISTELVKSKLRETTGAACKYGAFGLPTTVAHVDGKTYMLFGSDRMELLAYLLGEKWMGPVPPTLNARL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCM2-1", "uniprot_id": "GSTK1_MOUSE", "id": "Q9DCM2-1", "name": "Glutathione S-transferase kappa 1", "aln": "MGPAPRILELFYDVLSPYSWLGFEVLCRYQHLWNIKLQLRPTLIAGIMKDSGNQPPAMVPRKGQYIFKEIPLLKQFFQVPLNIPKDFFGETVKKGSINAMRFLTTVSMEQPE---MLEKVSREIWMRVWSRDEDITEYQSILAAAVKAGMSTAQAQHFLEKISTQQVKNKLIENTDAACKYGAFGLPTTVAHVDGKTYMLFGSDRLELLAYLLGEKWMGPVPPTANARL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2Q3-1", "uniprot_id": "GSTK1_HUMAN", "id": "Q9Y2Q3-1", "name": "Glutathione S-transferase kappa 1", "aln": "MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLPRKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPE---MLEKASRELWMRVWSRNEDITEPQSILAAAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGAFGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A3X2-1", "uniprot_id": "A0AB13A3X2_DANRE", "id": "A0AB13A3X2-1", "name": "Glutathione S-transferase kappa", "aln": "MSSSRKVVELFYDVVSPYSWLAFEVLCRYKNVWNIDLKFKPSFLGGVFHGSGNTEPGMVDNKLHYMITDLKLMSEYYGVPVNPPS-----PCKKDTLPAMRFVTAIAEKNQEENVLVEKVSRELWKRMWQKHQDITQPLSLTEAGLLVGLSSNEVEELLTNAKSQPIKDKLKSVTQEALEKNAFGLPFIVCHVNGKVEVFFGCDRFELIAHCIGEKWAGPCPIKTTM--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. : :******:******.**:****:::***.*:::*::: *:::.*** *.:: .* *: .:: *: . :*: *. :*.:: ****:*:: :: * ::**.***:* *:*.:.:***: .: *. .*::: :.: :* : : :*.:* . * * . .***** *.**:*:. ::**.**:**:*: :**** ** * . ", "identical_positions": 82, "similar_positions": 84, "identity": "35.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-142", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q92622-1", "uniprot_id": "RUBIC_HUMAN", "id": "Q92622-1", "name": "Run domain Beclin-1-interacting and cysteine-rich domain-containing protein", "aln": "MRPEGAGMELGGGE-ERLPEESRREHWQLLGNLKTTVEGLVSTNSPNVWSKYGGLERLCRDMQSILYHGLIRDQACRRQTDYWQFVKDIRWLSPHSALHVEKFISVHENDQSSADGASERAVAELWLQHSLQYHCLSAQLRPLLGDRQYIRKFYTDAAFLLSDAHVTAMLQCLEAVEQNNPRLLAQIDASMFARKHESPLLVTKSQSLTALPSSTYTPPNSYAQHSYFGSFSSLHQS-VPNNGSERRSTSFPLSGPPRKPQESRGHVSPAEDQTIQAPPVSVSALARDSPLTPNEMSSSTLTSPIEASWVSSQNDSPGDASEGPEYLAIGNLDPRGRTASCQSHSSNAESSSSNLFSSSSSQKPDSAASSLGDQEGGGESQLSSVLRRSSFSEGQTLTVTSGAKKSHIRSHS--DTSIASRGAPESCNDKAKLRGPLPYSGQSSEVSTPSSLYMEYEGGRYLCSGEGMFRRPSEGQSLISYLSEQDFGSCADLEKENAHFSISESLIAAIELMKCNMMSQCLEEEEVEEEDSDREIQELKQKIRLRRQQIRTKNLLPMYQEAEHGSFRVTSSSSQFSSRDSAQLSDSGSADEVDEFEIQD-------------------------ADIRRNTASSSKSFVSSQSFSHCFLHSTSAEAVAMGLLKQFEGMQLPAASELEWLVPEHDAPQKLLPIPDSLPISPDDGQHADIYKLRIRVRGNLEWAPPRPQIIFNVHPAPTRKIAVAKQNYRCAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMAIPSRVLRKWDFSKYYVSNFSKDLLIKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLCHMKNMFKTCRLAKELLDSFD-TVPGHLTEDLHLYSLNDLTATRKGELGPRLAELTRAGATHVERCMLCQAKGFICEFCQNEDDIIFPFELHKCRTCEECKACYHKACFKSG-SCPRCERLQARREALARQSLESYLSDYEEEPAEALALEAAVLEAT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80U62-1", "uniprot_id": "RUBIC_MOUSE", "id": "Q80U62-1", "name": "Run domain Beclin-1-interacting and cysteine-rich domain-containing protein", "aln": "MRPEGAGMDLGGGDGERLLEKSRREHWQLLGNLKTTVEGLVSANCPNVWSKYGGLERLCRDMQNILYHGLIHDQVCCRQADYWQFVKDIRWLSPHSALHVEKFISLHESDQSDTDSVSERAVAELWLQHSLQCHCLSAQLRPLLGDRQYIRKFYTETAFLLSDAHVTAMLQCLEAVEQNNPRLLAQIDASMFARKQESPLLVTKSQSLTALPGSTYTPPASYAQHSYFGSSSSLQSMPQSSHSSERRSTSFSLSGPSWQPQEDRECLSPAETQTTPAPLPSDSTLAQDSPLTAQEMSDSTLTSPLEASWVSSQNDSPSDVSEGPEYLAIGNPAPHGRTASCESHSSNGESSSSHLFSSSSSQKLESAASSLGDQEEGRQSQAGSVLRRSSFSEGQTAPVASGTKKSHIRSHS--DTNIASRGAAG---------GPR---NITIIVEDP-----IAEGGQYLCSGEGMFRRPSEGQSLISYLSEQDFGSCADLEKENAHFSISESLIAAIELMKCNMMSQCLEEEEVEEEDSDREIQELKQKIRLRRQQIRTKNLLPAYRETENGSFRVTSSSSQFSSRDSTQLSESGSAEDADDLEIQD-------------------------ADIRRSAVSNGKSSFS-QNLSHCFLHSTSAEAVAMGLLKQFEGMQLPAASELEWLVPEHDAPQKLLPIPDSLPISPDDGQHADIYKLRIRVRGNLEWAPPRPQIIFNVHPAPTRKIAVAKQNYRCAGCGIRTDPDYIKRLRYCEYLGKYFCQCCHENAQMVVPSRILRKWDFSKYYVSNFSKDLLLKIWNDPLFNVQDINSALYRKVKLLNQVRLLRVQLYHMKNMFKTCRLAKELLDSFD-VVPGHLTEDLHLYSLSDLTATKKGELGPRLAELTRAGAAHVERCMLCQAKGFICEFCQNEEDVIFPFELHKCRTCEECKACYHKTCFKSG-RCPRCERLQARRELLAKQSLESYLSDYEEEPTEALALEATVLETT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0N5E8A0-1", "uniprot_id": "A0A0N5E8A0_DANRE", "id": "A0A0N5E8A0-1", "name": "", "aln": "-------MEIQEQE----DGERRWELWKLLYNLKTTVEGLLSTNNPNVWSRYGGLQRLHKDMNNILGHGLKHEQIYYKQKDYWRFVWCVRYLCPHLARHVEQFSQLEPVLSSSVQSFGEGYKAERWLLHSLQAHVLSAQLKPLLQHKMNTQKYYNDGAFLLSEPHVSAMFQCLEAVEQNNPRMLALIDTVRLSHLKESPLGLMKSQSLCLLPGAPGHCRPADASQSHRLTTS--------------QSCLTEISNSP-------------QSKSSSDVAPSSSAQGRG-----NQVAGISFTEPVLP---ESRDFGDGDLDDGPEYLAIGNLGKQKRRDSSSSVHSSEHMGTRGDAHTPLAPPPQRRCSFSEAQKATGRSSRGHIRSLSDTGVTQKQKNGGGHRKITIIIEDPVAESVAATACSKS-------CGPFS--PQSSDSSANSSLYMESNGSQYTSVPDGLFRRPSEGQSLISYLSEQDFGSCADLEKENAHFSISESLIAAIELMKCNMRRPAEEAE--EEGDSDSEIQQLKQKIRLRRLQIRRTRLKPAAAASSNQVQSVDSGGSQRSSQDSFHPSDSGSDREVEDIELRDGSDGQSLLAVSQSGLSLSLASLFSDADIKR-SASSSRSFLSSESISPSMLQSNSAESVAMGLLRQFEGMQLPAASELDWLVPEHDAPQKLLPIPDSLPISPDDGEHADIYKLRIRVRGNLEWAPPRPQIIFNIHPPPKRKVVIAKQNYRCAGCGIRIEQDYMKRLRYCEYLGRYFCQCCHENAQSVIPAKIIRKWDFSKSYVSNFSRDLLAKISGDPLFNLSDINSALYKKVKALDTVRALREQLNLMKNLLKTCRLAKDVLEEFDSLLPGHLTEDMQLFSLSDLNAVRSGSLTPQLRHLLRLGSTHVTHCMLCQAKGFICEFCGNDKDIIFPYELNKCLRCEDCHACYHKSCFKTGTQCPRCLRLTERRERMARRNME----EQEDEACGT-----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: : : * * *:** *********:*:* *****:****:** :**:.** *** ::* :* ***:** :*:*.** * ***:* .:. .*..:. .* ** ** **** * *****:*** .: :*:*.: *****:.**:**:************:** **: ::: :**** : ***** **.:. : *.:*: : * :* :*... : :: * *: .:. ::::. ::*.*: . .*:: . .* .:********* : * *..* *. . .: :. : : .* *: .*. . : *. . *. .* :* * .. .:*: ... ** : . :*.:* . :*:************************************************* . * * ** *** ***:********* *** ..* * :.: * *..** **:** : *:*** :.:::*::* ***:* :.*..:* .* :.:* .:*:*.***:******:*************:**************************:***************************:**.*.**:.:************* : **:**********:*********** .:*::::******* ******:*** ** .*****:.*******:*** *: ** ** ** ***::*******::*:.** :*******::*:**.**.*.:.*.* *:* .* * *::** :************** *:.*:***:**:** **:*:*****:***:* **** ** *** :*::.:* : *:*. : ", "identical_positions": 483, "similar_positions": 219, "identity": "48.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-143", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91XQ2-1", "uniprot_id": "EPM2A_RAT", "id": "Q91XQ2-1", "name": "Laforin", "aln": "-------MLFRFG-VVVPPAVAGTRLELLLAGSR-PELGRWEP---RGAVRLRPAGTAAGAAALALQEPGLWLAEVELAPEEEAADGAEPGRIDTFWYKFLQREPGGELHWEGNGPHHDRCCTYNENNLVDGVYCLPVGHWIEATGHTNEMKHTTDFYFNIAGHQAMHYSRILPNIWLGSCPRQLEHVTIKLKHELGITAVMNFQTEWDIIQNSSGCNR-YPEPMTPDTMMKLYKEEG---LAYIWMPTPDMSTEGRVQMLPQAVCLLHALLENG----HTVYVHCNAGVGRSTAAVCGWLHYVIGWSLRKVQYFIMAKRPAVYIDEEALAQAQQDFFQKFGKVHSSICTL-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUA5-1", "uniprot_id": "EPM2A_MOUSE", "id": "Q9WUA5-1", "name": "Laforin", "aln": "-------MLFRFG-VVVPPAVAGARQELLLAGSR-PELGRWEP---HGAVRLRPAGTAAGAAALALQEPGLWLAEVELEAYEEAG-GAEPGRVDTFWYKFLQREPGGELHWEGNGPHHDRCCTYNEDNLVDGVYCLPVGHWIEATGHTNEMKHTTDFYFNIAGHQAMHYSRILPNIWLGSCPRQLEHVTIKLKHELGVTAVMNFQTEWDIIQNSSGCNR-YPEPMTPDTMMKLYKEEG---LSYIWMPTPDMSTEGRVQMLPQAVCLLHALLENG----HTVYVHCNAGVGRSTAAVCGWLHYVIGWNLRKVQYFIMAKRPAVYIDEDALAQAQQDFSQKFGKVHSSICAL-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2BHX0-1", "uniprot_id": "A0A8M2BHX0_DANRE", "id": "A0A8M2BHX0-1", "name": "Laforin", "aln": "-----MMVVFRFG-VILTPECP--DIEVFVLGSR-PEMGLWDT---ERAVKMNPS------QGRSCREPCLWTGDVLLS---------EP-LTDPLWFKFIKRVDG-DFIWEGSGPHHNRCCVYDDRNMVDGIHCHPIGHWIQETGHTDEMKHTTNFYFSIAGQQAMHFSQVLPRVWLGSCPRRVEHVTLKLKQELGVTAVMNFQTEWDVINNSHGCRRDLSQPMTPETMMHLYRDSG---LSYIWMPTQDMSTEGRIQMLPQAVFLLFGLLENG----HSVYVHCNAGVGRSTAAVCGLLMYVFGWKLRKVQYFLTARRAAVYIDEEALLRARDDFHMKFGQLCPSVRNTETQDSTL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B3EWF7-1", "uniprot_id": "EP2A2_HUMAN", "id": "B3EWF7-1", "name": "Laforin, isoform 9", "aln": "MHPKEGAEQHVFSPVPGAPTPPPNRCGRLVLGPRLPAAGTPGPGIRAAAARHALPLWGGGATRRGRRPAGAAGGGVAARAGALGAARCRP--PEAGRHRGGRRGPG----PAGAGPVARGGGAGGRGGGAGRGGAGPRGHVLVQVPEAGAGRRALLGRYCQQTPAPGAERELRPAPPTGASASGRPRRPRRRASRAFCPRPCALPGRPGLTLLCRPRCRRQPRLRLPTDSLDPYSAPGRLPAHSVACPSDLVSAHPVLSFFPTAPASRASALRLPPGAPFALRVPLDLRVPPFAGPLAARPRAADGFNSPTPPWLGFVSSFSCSNSLKKTQNDPTNETSVFANPRQQCAT--------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *. * .* . :: *.* * * . *.: . . : . . * .* :. .: :* * * ** . . . .. . * ** : . .:. ::: : . .: * *:.. : . : . . : . .: . * .. * :. * * : *: :*:. :.::* * . *. .:: * : * :..:.. . *:. . :: . : . . . : *.: . ", "identical_positions": 33, "similar_positions": 92, "identity": "9.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-148", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UPU7-1", "uniprot_id": "TBD2B_HUMAN", "id": "Q9UPU7-1", "name": "TBC1 domain family member 2B", "aln": "MPGAG-ARAEEGGGGGEGAAQGAAAEPGAGPAREPARLCGYLQKLSGKGPLRGYRSRWFVFDARRCYLYYFKSPQDALPLGHLDIADACFSYQGPDEAAEPGTEPPAHFQVHSAGAVTVLKAPNRQLMTYWLQELQQKRWEYCNSLDMVKWDSRTSPTPGDFPKGLVARDNTDLIYPHPNASAEKARNVLAVETVPGELVGEQAANQPAPGHPNSINFYSLKQWGNELKNSMSSFRPGRGHNDSRRTVFYTN--EEWELLDPTPKDLEESIVQEEKKKLTPEGNKGVTGSGFPFDFGRNPYKGKRPLKDIIGSYKNRHSSGDPSSEGTSGSGSVSIRKPASEMQLQVQSQQEELEQLKKDLSSQKELVRLLQQTVRSSQYDKYFTSSRLCEGVP-KDTLELLHQKDDQILGLTSQLERFSLEKESLQQEVRTLKSKVGELNEQLGMLMETIQAKDEVIIKLSEGEGNGPPPTVAPSSPSVVPVARDQLELDRLKDNLQGYKTQNKFLNKEILELSALRRNAERRERDLMAKYSSLEAKLCQIESKYLILLQEMKTPVCSE-DQGPTREVIAQLLEDALQVESQEQPEQAFVKPHLVSEYDIYGFRTVPED-DEEEKLVAKVRALDLKTLYLTENQEVSTGVKWENYFASTVNREMMCSPELKNLIRAGIPHEHRSKVWKWCVDRHTRKFKDNTEPGHFQTLLQKALEKQNPASKQIELDLLRTLPNNKHYSCPTSEGIQKLRNVLLAFSWRNPDIGYCQGLNRLVAVALLYLEQEDAFWCLVTIVEVFMPRDYYTKTLLGSQVDQRVFRDLMSEKLPRLHGHFEQYKVDYTLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKVIFRFALALFKYKEEEILKLQDSMSIFKYLRYFTRTILDARKLISISFGDLNPFPLRQIRNRRAYHLEKVRLELTELEAIREDFLRERDTSPDKGELVSDEEEDT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5Q6-1", "uniprot_id": "A0ACD6B5Q6_DANRE", "id": "A0ACD6B5Q6-1", "name": "", "aln": "MQEEDESSANTSRNSRILTAKSFDVADCDGKKGQASKLCGYLNKLTGKGPLRGFKTRWFVYDPRKCFLYYFKTPQDALPIGHIEIGDACFSY---DVEAEEG-----LFEIHTEGKEFLLKAPNRQVMHYWLQQLQQKRWEFCNMPGPR--DSWCSPTPLYPHTGLVARDAEAMPYEKPSESMESVRNDFALELDNDGLIGHQTAHVPVAQP--TAALSSLRQWGSEIRNSMSHLRPGR-AGENRRSVFYTGGSEDWEMVDPPTKDPAPSDCQHRES--SSHFNRSSIGSAFTFDF-RNPSKIKRPFHS--GSGKPNHS-AESSPVEYNETKISKLQLRIQSQQEEISQLQEQENKLREELGSQKELVRLLQKTLRSAQCDWPSTVGPHNHYLEENEVDKALTERDTQIKDLCSHMEKLALEKESLQQELKGLKIKVGEINEQLGMLMETIQAKDEVIMKLSQPSGEGETQSAECNSPSVT---REQQELNTLKDSLQGYKSQNKFLNKEIIELTVLRRNAESREKLLEAKYNSLEAKLCQVESKYLVLLQEVKSPVCSSSEQTHSGDVITRLLEDALQVESTDQQEHPVLKPNAVSEYDIYGFKTVPEEEDEEEKLEAKKRALDLKSLSLT-DQETSVRVKWDNYLAITMNREMVRSPDLKALMRGGVPHIHRSKVWSWCVSFHVKKMRDCQPKDYYHNLLCMANDKPNPACKQIELDLLRTLPNNKHYSSPDSDGIQKLRSVLLAFSWRNPDIGYCQGLNRLAAIALLYLDQEDAFWCLVAIVEVFMPHDYYTKTLLGSQVDQRVFKDLMYEKLPRLHAHFEHYKVDFSLITFNWFLVVFVDSVVSDILFKIWDSFLYEGPKIIFRFALALFKYKEEEFLKLQDPMTIFKYLRYFTRTILDARKLMAMAFVDMNPFPLRQIQNRRTFHLEKVRLELTELEAIRQTFLRERESTMDGRTLISDDEEES", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : *: . .. :*:. . * :.::*****:**:*******:::****:*.*:*:*****:******:**::*.****** * ** * *::*: * :*******:* ****:*******:** . ** **** .****** : * :*. * *..** :*:* . *:*.*:*: *.. : : **:***.*::**** :**** .:.**:****. *:**::**..** * *..:. :.. *:. **.*.*** *** * ***::. ** * .** .:.*. . : .:: .. * ::.. **: ::*:::*.**********:*:**:* * * . . : ::. : * ::* ** .* *::*:::*********:: ** ****:******************:***: .*:* . :. .****. *:* **: ***.*****:*********:**:.****** **: * ***.********:*****:****:*:****. :* : :**::********** :* *:..:**: *********:****: ****** ** ******:* ** :**.*. ***:**:* *:****: **:** *:*.*:** ******.***. *.:*::* .:::.** * :* ***.******************.* *:******.*********************.*:*****:*********:*******:*****************:*** *******.***:****::*********************************:***************:*****.*:******************::::* *:********:***::****************: *****::: * *:**:**::", "identical_positions": 578, "similar_positions": 220, "identity": "59.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-157", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14CB8-1", "uniprot_id": "RHG19_HUMAN", "id": "Q14CB8-1", "name": "Rho GTPase-activating protein 19", "aln": "MATEAQSEGEVPARESGRSDAICSFVICNDSSLRGQ-----PIIFNPDFFVEKLRHEKPEIFTELVVSNITRLIDLPGTELAQLMGEVDLKLPGGAGPASGFFRSLMSLKRKEKGVIFGSPLTEEGIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQILRDALNNGTDIDLESGEFHSNDVATLLKMFLGELPEPLLTHKHFNAHLKIADLMQFDDKGNKTNIPDKDRQIEALQLLFLILPPPNRNLLKLLLDLLYQTAKKQDKNKMSAYNLALMFAPHVLWPKNVTANDLQENITKLNSGMAFMIKHSQKLFKAPAYIRECARLHYLGSRTQASKDDLDLIASCHTKSFQLAKSQKRNRVDSCPHQEETQHHTEEALRELFQHVHD-MPESAKKKQLIRQFNKQSLTQTPGREPSTSQVQKRARSRSFSGLIKRKVLGNQMMSEKKKKNPTPESVAIGELKGTSKENRNLLFSGSPAVTMTPTRLKWSEGKKEGKKGFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BRH3-1", "uniprot_id": "RHG19_MOUSE", "id": "Q8BRH3-1", "name": "Rho GTPase-activating protein 19", "aln": "MAAEAPSGGEAPVCDSGRSDAICNFVICNDSPLRGQ-----PIIFNPDFFVEKLRHEKPEVFTELVVSNITRLIDLPGTELAQLMGEVDLKLPGGAGPAAGFFRSLMSLKRKEKGVVFGSPLTEEGIAQIYQLIEYLHKNLRVEGLFRVPGNSVRQQLLRDALNNGTDIDLDSGEFHSNDVATLLKMFLGELPEPLLTHKHFHVHLKIADLMQFDDKGNKTNIPDKERQIEALQLLFLILPPANRNLLKLLLDLLYQTAKKQDKNKMSAHNLALMFAPHVLWPKNVTANDLQENIIKLNTGMAFMIKHSQKLFKAPAYIRECARLYYLGSRTQMSKDDLDLTTSCHNMSFQLARCQRQNRVDPSSQQEETQQHTEEALRELFQHVHN-WPDSAKKKQLLRQFHKQSLTQTPGREPSTPRVQKRARSRSFSGLIKRKVLGSQMTSEKKNSSPAPESVAMGELKKASKENMNLFFSGSPAGTVTPTRLKWSEAKREGRKGFF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F6NW06-1", "uniprot_id": "RHG19_DANRE", "id": "F6NW06-1", "name": "Rho GTPase-activating protein 19", "aln": "MATEKDTD----VNKRDRRGTVCNVVINQESETGSSGEGRPPIIFNPDFFVEKMRHERPEAFTELVLSNITRLIDLPGAEFSQLLGDEEPKTPN-----AGFFRSFNFLKRKDKGVVFGMPLTEEGIAQIYQLIAYLSKNLHVQGLFRVPGNSLRQQTLREQLNSGADIDFAAGDFHPNDVATLLKSFLGELPEPLLTHRHLHAHLKITELTTFDDEGNKTSFPDKERQIEALQLLLLLLPTANRTLLKLLLDLLYHTAKQQDKNKMSAHNLALMFGPHVIWPKNMNASDLQENLKKLNSGMAFLIKHSQKIFRAPAYLREHARLQFANTKILQSKDDLELLS-VSGSPFISACKRSGERVR-----LDSDNHTEEALKELYRHVTDNMPNSAKKKKLIRQLGKPSTPGTPVNENLTPSSKKHGRSRSFGGLIKRKVLGGQP-ADRRGRHVSPQSAAGLGKENISSEMAN------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* : . . .* .::*..** ::* .. ************:***:** *****:***********:*::**:*: : * *. :*****: ****:***:** ************** ** ***:*:*********:*** **: **.*:***: :*:**.******** ************:*::.****::* ***:****.:***:*********:*:**..**.**********:***:********:******.***:****:.*.*****: ***:****:******:*:****:** *** : .:: *****:* : .* * : :** ::::******:**::** : *:*****:*:**: * * . ** .* *. :*:.*****.*********.* :::: :*:*.* : *.* * ", "identical_positions": 274, "similar_positions": 105, "identity": "54.8%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-16", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63251-1", "uniprot_id": "KCNJ3_RAT", "id": "P63251-1", "name": "G protein-activated inward rectifier potassium channel 1", "aln": "--------------------------------------------------------------------------------------------------MSALRRKFGDDYQVVTTSSSGSGLQPQGPGQGPQQQLVPKKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTP----------CVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQ-TEQFEVVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISL--EEGFFKVDYSQFHATFEVPTPPYSVKEQEEMLLMSSP------------LIAPAITNSKERHNSVECLDGLDD--ISTKLPSKLQKITGREDFPKKLLRMSSTTSEKAYSLGDLPMKLQR--ISSVPGNSEEKLVSKTTKMLSDPMSQSVADLPPKLQKMAG----------------------GPTRMEGN---LPAKLRKMNSDRFT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63250-1", "uniprot_id": "KCNJ3_MOUSE", "id": "P63250-1", "name": "G protein-activated inward rectifier potassium channel 1", "aln": "--------------------------------------------------------------------------------------------------MSALRRKFGDDYQVVTTSSSGSGLQPQGPGQGPQQQLVPKKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTP----------CVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQ-TEQFEVVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISL--EEGFFKVDYSQFHATFEVPTPPYSVKEQEEMLLMSSP------------LIAPAITNSKERHNSVECLDGLDD--ISTKLPSKLQKITGREDFPKKLLRMSSTTSEKAYSLGDLPMKLQR--ISSVPGNSEEKLVSKTTKMLSDPMSQSVADLPPKLQKMAG----------------------GPTRMEGN---LPAKLRKMNSDRFT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48549-1", "uniprot_id": "KCNJ3_HUMAN", "id": "P48549-1", "name": "G protein-activated inward rectifier potassium channel 1", "aln": "--------------------------------------------------------------------------------------------------MSALRRKFGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTP----------CVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQ-TEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISL--EEGFFKVDYSQFHATFEVPTPPYSVKEQEEMLLMSSP------------LIAPAITNSKERHNSVECLDGLDD--ITTKLPSKLQKITGREDFPKKLLRMSSTTSEKAYSLGDLPMKLQR--ISSVPGNSEEKLVSKTTKMLSDPMSQSVADLPPKLQKMAG----------------------GAARMEGN---LPAKLRKMNSDRFT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5I4-1", "uniprot_id": "A0ACD6B5I4_DANRE", "id": "A0ACD6B5I4-1", "name": "G protein-activated inward rectifier potassium channel 1", "aln": "--------------------------------------------------------------------------------------------------MSALRKKFGNDYQVVTTTSS-SHLKDK------------RRKRQRFVDKNGRCNVQHGNLGGETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMAFMWWVIAYIRGDLNRTHDEKYTP----------CVANVYNFPSAFLFFIETEATIGYGHRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSENAAISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDTKSPFYELSQHSMQ-TEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISL--EEGFFKVDYSQFHATFEVPTPPYSAKEQDEALLMSSP------------LMAPSLCNSGEKNSSLDCLELLEDPESTTKLPAKVQKMTGRDGLPRKLLRMSSTTSEMTYSLGELPIKLQR--ISSVPGVLEEMQVTKTTRISSEAISKSVADLPPKLQRLSG----------------------GGGRMDGH---LPPKLRKMNSDRFT", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KH86-1", "uniprot_id": "A0A0B4KH86_DROME", "id": "A0A0B4KH86-1", "name": "", "aln": "MPKMIVDKSELVGENAWAKLLPDEKDKAIIVKMNKSSSNNNDSKETTPLNVDQLVAASNPAVAGEQSAVCLEDTYKRTSTYASNINSTGGESSGSGTQLSRKESILGSFHRQIRRSIKAVSESPGPLTRYRQTRFSSRRVRKRVVFKHGECNVVQGNVAKRRRRYLQDIFTTLVDAQWRWTLLVFAASFVFSWAFFGFIWWIIAYAHNDLEYTNLKNQSPDLVANITHTVCVTQVSNMMSAFLYSVETQTTIGYGNRYVTEECPEAIFTMCIQCITGVFIQAFMVGIVFAKLSRPKKRAQTLLFSRNAVICHRDGVPCLMFRVGDMRKSHIIEAHVRAQIIRKKVTKEGEVLPFYQQELHIGADGGEDRLMFIWPTTIVHKIDRNSPLYMLSASDML-KERFEVVVMLEGVIESTGMTTQARSSYLPSEVLWGHRFVNVVSFRKETGEYEVDYTLFNNTYDVDTPLCSAKQLDELKSEYSKSAKCVNAPFADRTLSASLFQRIASAASVDHLDPASDESLDSGRLQIRSHSIPNGVLASELEPLNNNKHGASFTMGGLTITTTAPSIPNLSSINEKTNSGNSINSSNYSNNNSLSTLTGGGSAASGPGGGITIVAGSGNHGGAGGGGGGGGRHKSNPRRLSIKQDQLPIDSIC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7YZX2-1", "uniprot_id": "B7YZX2_DROME", "id": "B7YZX2-1", "name": "", "aln": "-------------MQSDASPLGAAATDSLTMHRSTSMPVKPKPLEQKPLLR-----------SSEKETVNASDYYPESPGFVR--RRRSKAAGDHLETRSEQNPTFSFPYAHDWAGSTIELTPDLGSGPRTSSSDGLRRSLNRVMEKNGKENVVFRRIPEKSWRYMRDLVTTLMELEWKYMLTLFLGSYFLSWLLFAALCYVVAYSHGDFIFDPVSGKRMG----EGVDPCIYGVHSWVAMIIYSVETQTTLGFGEKYASEECPETIFLFVMQMLSAALIEGCMVSVIYAKTARPARQLTKLKFSDKAVICYRDGRLCLLFRVCDPREQQSIESKIRVYIIVDKRTREGETIKS-HVELKL---EGNGEQIILWPDVVCHVIDETSPLSQFTTAKLFNAAQFELYVSIVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYDAQNERYIVDYENFNRTISVDMPMTNPKN-DHLKLEYRK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . :. : . :: :*.: *:*. ** .: . **: *:.***:: :*:: * :* :: .:* ::. : :::** :.*: *: * . : ::: :**::*:*:* :* :::*** *: : :* : . :::. ::. :: * ::* :: .* ** :*.*. *** *:*** : *:.: :.:::* :: .: * *** : : **.: * .. ::: * .: * ** .**: :: .: :**: * : * :*. :*::** *::**:**. :: : : *** *: * .* * . *: :. ", "identical_positions": 82, "similar_positions": 128, "identity": "12.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-163", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A567-1", "uniprot_id": "A0A8I6A567_RAT", "id": "A0A8I6A567-1", "name": "", "aln": "MEDFRGIAEESFPSFLTSSLLGNSEVLGNVTLQSNFGLPIAVSTLAKNRPSTDNRCPDVQASYLIEGRLSVPSASSPGCQSESSEPRERAQLSFQGDDSATRKNNYVES---AHALVKQ---------REEEEQDNTASVQGQSLLGGLSLLQQVPDSALDFHLKSWINNQDHKIAMPDAKKYLEAKNPNSDFSHTSLLDNEKLLTLSNLD-DSSDDDINDEEFYDDHLEAYFEQLAIPGMIYEAG-GQESPENV--------------------------------FKFPIS------------------------------------------------------------------------------------------NSSQECGGEAVLMRR----------LHAVDEVLRSTYHHCTNETKGGFDPADYIKQDSESPQQNKYLAPDLGTVLNVDRCLNTETP----------------TVSIQRDGNIAS-LDANGDNGINSPDTVWSPTCERRACEFYESGAKT---------------------------------------NDDTDLSQNVVYQNEDGKWVTDLAYYTSFIDQQGVQMSPNNEMN---EDFRSGSDALDLIAKDEEEFNKEHPFIQDEKIDVQNTSAALGDASWVATVN-YHLLRKSLGTSEFDKDDGSYLRLSLGEFFAERSEALGCLGGGKD--VKRPSFGYFIRSPEEREPVALIK-SDLSRSNLEKEVTHLRHGFSSGDLNEKSRAQLSKGSVTLEAEELQRTSQVDEDDRTLTASRSQTEDTLCSNNKFLEYENTLSGGGDSVLRISTIASAIADVSLSTDPAQLVAMMKALTNK-RGKTFQDD-ERQDRSVISHFLPNDLEKSNRS------NACDMEKYLIQTELSSCEGAQGPFSTADTSDIWDLSVPEQQTVQDMSMVNVCATNT--REAEEDTAAIFHDENIESDTQESLRTMTCSNSVLTNIRENRNTAMRGVTCSAG-ELLDMQNSEGAASVSIPAPASRSDSSLRDPRGPSFSIAQQCEEIQDNIEQGRKKECVSETGSGDKHVTFEDTHVVLPKSVDLQTASPDSGKSGSQD-QESFRLSMSPLSHSSPSEISGN--FSGCALQSLDSACHQR-LHLESDLSQLACSHADMSRLTYVSGQENTLPVTAADESSEDHKSDLTSELSTTIVRASPTPPEEQTVEKLRDKIPGQNA-EQVSLPCVTQSKPGLGNMTETLSLRNGFEDGEPNFTSSQNI-SSKSGKPLETGKK-ESTSSSSEQDLIGQALLNKAGLNHRSGPAILNLPVLSQKTVGQSQRLTPTCLSTASSESSSQIPDLGTSGNQHNPAPHILAHASVAKVQNQ--PAVCPTLWTGHSVYTAPGAPQYLGPVSSSGNATLSQCHAG-MQVCGISGFSPYPPVASEHLAS----GMYLGPNLASGLMAPSSVYNKCSTAVHQNLLSTAKPFPVQSVGTNCETEPWDSGMS-GFGNARVPEELRFPHACCVGIASQTLLSVLNPTDCWLQVSIKVLSICVNGEKVDLSTQTCLVFKNKVVIRPHATEEIKILFIPTNSGIFRCTFSVASWSFSADADTIAQAEALGSRVTLTAIAETPVIEVETEKKGVLDFGDLTYEGWKALPLKLINRTHATVPIRLIINANALAWRCFAFSKEPIRASLKAAP-YADVVAQLVAPSVVSHVMPASYDGKDPEFLIVWVIFHSPKK-ILTSEILGSAEEFLARVDIEVDSPNPIPVLRSVDLRARAGVARIHAPRDSQTIYLLADVNSSTKQPLPLKNAGNIEVYLDIKVAEQGSQFSVDPESLFLKPGEEHEVTVSFTPKDPKACEERILIIFVQPLGPQYEVVLKGEVVTSGSKPLP---PGPHCSDISLILSNKQFLTWGGVPLGRSQLQKLALRNSSTTTAQNLQLFIKGQDQDCFQIQNTFGSEERLTSNCEIRICPGEDFVISVLFAPTRLSCMLAKLEIKQLGNRS-QPGIKFMIPLSGYGGTSNLILEDVKKLSDSYLVTVNDLIPGKES---KVTFSVRNTGSRAAFVRAVGFKGSQRKVLLDPKVLRIFPDKFVLKERTQKDITLVYNPSS-----RKIGSKPETELITVYMFGGDEISRQQYRRALLHKPGIIKQILPKQSVLQSIDFAEAFQDELLSDEACDLPQRLHDIQLFYGSMRKITLSVIG--EFRDSICSRTFLPPSSS----AESKSNLSSETGTSGKQGVSVLLDVLPVKGPQGAPFLSQTAHPAQGTPTSEERWAVHPEHLILVAPSSCDLAKTGCFQIINSSVTLLKFELYWPAHCLTVTPQHGYIMPESKIQILVSPNLSVSTKESGLPWTGLIYIHCDNGQKKIIKVQIREDLTQEPSPHSLSSGTFGVLAPAPEPSISHLTKPLTKPPSTKVEIRSKTVVFPPTEPGKTSENYLELENCGPTNVKWHLSSFAPPYVKGVDETGDVFRATYTAFRCSPISGTLEGHGLQKVSITFLPRDRGNYAQFWDVECHPAKEPHMKHTLRFQLSGQSITAEKDPEDSRSSRDTLIKVDPAVVSRRRAVSETSSHMPGRQPDLSHGGVYAPKDVYVFLPTKLGESRMLKVNLRNNSFFTHTLKFLSPREPFHIKHSRYSLRARHYIHIPVHFRPETVGRFEALLVIQTDEGKSIAVRLIGESLGKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q4Y4-1", "uniprot_id": "E9Q4Y4_MOUSE", "id": "E9Q4Y4-1", "name": "", "aln": "MEDFRGIAEESFPSFLANSLLGNSEVLGNVTLSSNFGLPIAVSTLARSRPSTDNRCPDVQESYLIEERFSVPSASSPSCQSDNPEPRERLRLSFQGDDSALRKKNYIESPDLSHALMKP---------RAEEKQANAASVQGQSLLGGVSPLQQVPDSALDFHLKSWTNHEEHNIAMPDPKKHFEAVNPNRDFSHTSLLDNEKLLTLTNLD-SSSDDDINDEEFYDDHLEAYFEQLAIPGMMYEAG-GQESPADD--------------------------------FKFPANED------SILNCEFQSENNSPRLPHDACTSGNSPTAHTESEGGHGCPPGTSGCVGTVDNKMQVDNVMSLYSHAWRNEKEAAHNLKDIVPNQSRGCGGEEIVVKR----------LCAVDETLRSTYRHST-ETEDGFDPADYIKQDSESPHQNKHFASDLETVPNVDRCLNTETP----------------TVFIQKDGDIAASSKTNGDNGINSPDTLWSPTSERRACGLYESDSKT---------------------------------------SDKGELSQNVVYKSEDGRWVTDLAYYTSFIDQQDLQMSPNNEMN---EDFRSGSDALDLIAKDEEEFNKEHPFIQDEKIDVQNTPVALGDNSWVATVN-YHLLRKSLGTSDFDKDNGSYLRLSLGEFFAERSEALGCLGGGKD--VKRPSFGYFIRSPEEREPVALIK-SDLSRSDLEKEATQPYRGFSSGDLNEQSQVQLSEGSVMLKAEELQRNSQVDEDDITLTASRNQTEDTLCSNNKLQEYKNTLSGGEDSVLRISTIASAFADVSVSTDPAQLVTMMKALRNKGRSKPFQDDGTQEDCPNISHVLLNDLEKSNRS------NAFDMEKYLTKTEFSSCEGAREPLSRAGTSDMWDLCSPERQTVQDRSMVNVCATNS--REAEETTAAIFCAENIESDTQESLRTIASSDSVLTSTRENRNSAMGRMPPSVD-TLLDVRNSEKAASVSIAA--SRSDSLLRNPRVPSFSIVEQCEEIQDNRDHGRKKECVSETSSSDKHVTFEDGLVVLPKSVDLKTASPESGRSGFQD-EESFRL--SPLSHSSPSEISGN--FAGCVLESLDSAYHQR-PHLESELSQLACSHADMSRLTYVSEQENTFPVTAADESSEDHKSDLTSELSTTIVRASPTPPREQAVEKPRDKIPGQNA-EKVSMPWVIQSKSGLANMRETPSLRTGFEDGEPNFTSSQDI-SSESREPLEAGKMMDSTSGSSEQDLIGQALLDKPALNHRSGPAVPNLPELIQKTVDQGQRLSSTRLSAASSEASSQVPNPGASGTQHNPAPHISAHASVAKVMNQ--PAVCPALWTGHSLYIAPGAP--------SGNATLSQCHAG-MQVCGISGYSPYPAAAPELVAS----GLYLGPSLASGLMAPSSLYNLCSTAAPQNLLSTAKPFPMV---TNCETEPRDSGMMPAFGNARVPEELRFPHACCVGIASQTLLSVLNPTDHWLQVSIRVLSIWVNGEKVDLSTQTCLVFKNKVVIRPQATEEIKILFIPTSSGIFRCTFSVASWLFSADADTVGQAEALGSRVTLTAIAETPVIEVETEKKGVLDFGDLTYAGWKALPLKLINRTHATVPIRLIINANAVAWRCFTFSKEPIHVSLKAAP-HADITAQLAAPSVVSHVMPASYDGKDPEFLVVWVIFHSPKK-LLTSEILGSAEEFLARVDIEVDSPNPIPVLRSVALRARAGVARIHAPRDLQTVYLLADVNSSTKHPLPLKNAGNIEVHLDIKVAEQGSQFSVDPESLFLRPGEEHEVTISFTPKDSKACEERILIIFVQPLGPQYEVVLRGEVISSGSKPLP---PGPHCSDIPLILSNKQFLTWGGIPLGRTQLQKLALRNSSTTTAQNLRLFIKGQDQDCFQIQNTFGSEERLTSNCEIRICPGEDFVISVLFAPTRLSCMLAKLEIKQLGSRS-QPGIKFMIPLSGYGGTSNLILEDVKKLSDSYLITMNDLIPGKES---KVVFSIRNTGSRAAFVRAVCFKESQRKVLLDPKVLRIFPDKFVLKERTQEHITLVYTPSS-----RKNGEKPATELLTVYMFGGDEISRQQYRRAQMHTPGILKQILPEHSVLQHIDFTEAFQDEPLIDEVCDLPQRPNDIELFYGSMRKITLSVIG--EFRGTICSREFLQPSSS----AESKSNFSSDSKTSGKQSGNVLLDVLPVKGPQGPPFLSQSAHPAQDTAASEEGWAVHPEHLILVAPSSCDLAKTGCFQIINNSVILLKFELYWPAHCLTVTPQHGCIMPESKIQILVSPNFSVSTKESVCPWTGLIYIHCDNGQKKIVKVQIREDLTQEPLPHLPSSGTSGILAPAPEPSISRLTKLITKPPSTKVEIRSKTVIFPPTEPGRTSENYLELENCGPTDVKWHLSSFAPPYVKGVDETEDVFRATYTTFRCSPISGTLEGHGIQKVSIIFLPRDKGNYAQFWDVECHPAKEPHMKHTLRFQLSGQSIRAENDPEDSCSSRDALIKVDTAVTSRRRAVSETAAHTPG-QLNSSHHGVYAPKDVYTFLPTKLGESRTLKINLRNNSFSTHALKFLSPREPFHIRHSKYTLRARHYIHIPVHFRPEAVGRFEALLVIQTDEGKSIAIRLIGESLGKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TEP8-3", "uniprot_id": "CE192_HUMAN", "id": "Q8TEP8-3", "name": "Centrosomal protein of 192 kDa", "aln": "MEDFRGIAEESFPSFLTNSLFGNSGILENVTLSSNLGLPVAVSTLARDRSSTDNRYPDIQASYLVEGRFSVPSGSSPGSQSD-AEPRERLQLSFQDDDSISRKKSYVESQRLSNALSKQSALQMETAGPEEEPAGATESLQGQDLFNRASPLEQAQDSPIDFHLQSWMNNKEPKIVVLDAGKHFEDKTLKSDLSHTSLLENEKLILPTSLE-DSSDDDIDDEMFYDDHLEAYFEQLAIPGMIYEDLEGPEPPEKG--------------------------------FKLPTNGLRQANENGSLNCKFQSENNSSLISLDSHSSETTHKESEESQ--VICLPGTSNSIGTGDSRRYTDGMLPFSSGTWGTEKEIEN-LKGIVPDLNSECASKDVLVKT----------LRAIDVKLNSDNFHDANANRGGFDLTDPVKQGAECPHQN-------KTVLHMDGCLDTETP----------------TVSIQENVDVAS-LKPISDSGINFTDAIWSPTCERRTCECHESIEKN---------------------------------------KDKTDLPQSVVYQNEEGRWVTDLAYYTSFNSKQNLNVSLSDEMN---EDFRSGSEAFDLIAQDEEEFNKEHQFIQEENIDAHNTSVALGDTSWGATIN-YSLLRKSRSTSDLDKDDASYLRLSLGEFFAQRSEALGCLGGGNN--VKRPSFGYFIRSPEKREPIALIRKSDVSRGNLEKEMAHLNHDLYSGDLNEQSQAQLSEGSITLQVEAVESTSQVDENDVTLTADKGKTEDTFFMSNKPQRYKDKLPDSGDSMLRISTIASAIAEASVNTDPSQLAAMIKALSNKTRDKTFQEDEKQKDYSHVRHFLPNDLEKSNGS------NALDMEKYLKKTEVSRYESALENFSRASMSDTWDLSLPKEQTTQDIHPVDLSATSVSVRAPEENTAAIVYVENGESENQESFRTINSSNSVTN--RENNSAVVDVKTCSIDNKLQDVGNDEKATSISTPS---DSYSSVRNPRITSLCLLKDCEEIRDNRENQRQNECVSEISNSEKHVTFENHRIVSPKNSDLKNTSPEHGGRGSEDEQESFRPSTSPLSHSSPSEISGTS-SSGCALESFGSAAQQQQPPCEQELSPLVCSPAGVSRLTYVSEPESSYPTTATDDALEDRKSDITSELSTTIIQGSPAALEERAMEKLREKVPFQNR-GKGTLSSIIQNNSDTRKATETTSLSSKPEYVKPDFRWSKDP-SSKSGNLLETSEV-GWTSNPEELDPIRLALLGKSGLSCQVGSATS-HPVSCQEPIDEDQRISPKDKSTAGREFSGQVSHQTTSENQCTPIPSSTVHSSVADMQNM--PAAVHALLTQPSLSAAPFAQRYLGTLPSTGSTTLPQCHAGNATVCGFSGGLPYPAVAGEPVQNSVAVGICLGSNIGSGWMGTSSLCNPYSNTLNQNLLSTTKPFPVPSVGTNCGIEPWDSGVTSGLGSVRVPEELKLPHACCVGIASQTLLSVLNPTDRWLQVSIGVLSISVNGEKVDLSTYRCLVFKNKAIIRPHATEEIKVLFIPSSPGVFRCTFSVASWPCSTDAETIVQAEALASTVTLTAIAESPVIEVETEKKDVLDFGDLTYGGWKALPLKLINRTHATVPIRLIINANAVAWRCFTFSKESVRAPVEVAP-CADVVTRLAGPSVVNHMMPASYDGQDPEFLMIWVLFHSPKKQISSSDILDSAEEFSAKVDIEVDSPNPTPVLRSVSLRARAGIARIHAPRDLQTMHFLAKVASSRKQHLPLKNAGNIEVYLDIKVPEQGSHFSVDPKNLLLKPGEEHEVIVSFTPKDPEACEERILKIFVQPFGPQYEVVLKGEVISSGSKPLS---PGP-CLDIPSILSNKQFLAWGGVPLGRTQLQKLALRNNSASTTQHLRLLIRGQDQDCFQLQNTFGSEQRLTSNCEIRIHPKEDIFISVLFAPTRLSCMLARLEIKQLGNRS-QPGIKFTIPLSGYGGTSNLILEGVKKLSDSYMVTVNGLVPGKES---KIVFSVRNTGSRAAFVKAVGFKDSQKKVLLDPKVLRIFPDKFVLKERTQENVTLIYNPSD-----RGINNKTATELSTVYLFGGDEISRQQYRRALLHKPEMIKQILPEHSVLQNINFVEAFQDELLVTEVYDLPQRPNDVQLFYGSMCKIILSVIG--EFRDCISSREFLQPSSK----ASLES--TSDLGASGKHGGNVSLDVLPVKGPQGSPLLSRAARPPLDQLASEEPWTVLPEHLILVAPSPCDMAKTGRFQIVNNSVRLLRFELCWPAHCLTVTPQHGCVAPESKLQILVSPNSSLSTKQSMFPWSGLIYIHCDDGQKKIVKVQIREDLTQVELLTRLTSKPFGILSPVSEPSVSHLVKPMTKPPSTKVEIRNKSITFPTTEPGETSESCLELENHGTTDVKWHLSSLAPPYVKGVDESGDVFRATYAAFRCSPISGLLESHGIQKVSITFLPRGRGDYAQFWDVECHPLKEPHMKHTLRFQLSGQSIEAENEPENACLSTDSLIKIDHLVKPRRQAVSEASARIPE-QLDVTARGVYAPEDVYRFRPTSVGESRTLKVNLRNNSFITHSLKFLSPREPFYVKHSKYSLRAQHYINMPVQFKPKSAGKFEALLVIQTDEGKSIAIRLIGEALGKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQD1-1", "uniprot_id": "A0A8M3AQD1_DANRE", "id": "A0A8M3AQD1-1", "name": "", "aln": "MENTQNIEEEPFPSFLSN---------------ASLGMPMAASTVAKIRPSIDNRVTDVQASYLEEAQSRMHSQGSDG-------SKEKIALSLKEDLDS--IDEFIAANRFSDLLVNVN----------FDETESAAFTKTSSSGGAVPLLVSNSVPLRTTDKDTMAAEATVFQVILEEEDSEETDSEKCSDSFSSFLANEKLMSLDSMNSDMTDDDIDVTQLHDEELELYFNKLIPPAMQRGRVEGQEISVELPSSSSQHNTTESERNWQSLQVDFNKRNTHMADVRLAAAGMDSSPVSEQVDTDDELETYQDHGRERFGCTSRQQVWEGHLPHFRPGLEGGSSDDDLPAGGENTKTSTGIEGYCPAEEQIISLPFTGNGARSEEENGGISVASLLPTAIQSTGDVLRGLGIVGGSGENRDDDQIQSLLTRSGMVNSQNEMNNPAEVWLDTINLKKDVSHSLQDLSASDNPFLHSTNSSFHLSKILQESHTKTEENVNIIQTVDHSTPSLLGGPCGDSLVLNAHKRTSSENVLPGESLEPRDPYQRFNENHEEQNDIWNHQPEMSRLELQQDANATHSVVYQNEEGKWVTDLAYYSSFEKEMEANMPEDVALEFQSEDFLAGGKAMDKIIEDQEEFEKEHQFLQEEQIQNVNMSEVLGDTSWKIPSSSNILMRASQVSSELESGNQSYLRISLGEFFQRRSEALGCLGHSEEDYVKRPSFGYFITSPEKREPVALLRPSDIFSRGNSIHVETIQQSDADETLNQD---DLDKTLEPNTAEPACANVQQKEEQVSQISTQHENNEDHTS--------EPPSSSSNLMLSISTIASAIADASLSSDPAQLGAMIVELSQQSRSKSHQQVKDLIRNPVAALQLNGLFEDLQKTTVVGDVSAPDMEKYLKKAEVSCSDSDESSSQSCFDVLTLADGLANSNNQVQQQLAPLKNTTMYKNEELSVMEEQEASKKCQVLAGKVFKNPRSDVKRSAIPRPKSSCLPTVTANPAKRSVGSDKRTSSYIPVKSKPFGLKPTNTGHCATSTNSKDVPESSIKTETALSATGSHSVKGDKSLSTSTLKSLPGLQNGGHSELTLLKTSPHKPRAQPNEPVIDQARLPKVSEATLSVSKEKSETINSNDELPGTQEQFGSPENSAPSSMEVTNCNFRPSTSPLTHSSPSQTSIQSGYGETFQGSPTSEMAQRNPAGDPGSPQSHCSSPSISRLTYLSINENTCVPTPDHRKKNTSMSLSTTIIRASPTPPMEPFSNDIVLRSMKSAEPLCHSEVAGLNVKTPMLDVRSESELDGNAYNNNR-QSEPGSNIYAQGDSGYSSKLTNQHLPGAAIEQMHQALPQILGCGSCLSKSDDLTHGSVPGYNSQRVLTNFPNFLTEHSLFSSHLAKRYLS--------AEGPLHAPSCQIAGPSGLYRVSASGSNTSMV------HMPSSLQSGYLSNIQQCPAQYVISKNYTHPNAESWTTG-------------DLADIRTQVLVPSELKFHSSCCVGIASHTSLNIFNPSKHWQQVSISMTSISIDGEKVESLPFQWLIVKNKAIIGPKCSEEHKVLFIAPKAGLYQCTLSVSSWPASADAETIAQAEAFAKKVVLIAVAENPSIEVDVGKTGCLDFGDLVEGSTKALPLKLVNRTHATVPIRLVISANASAWHCFGLSKSPVAMSMDSSFNFGSAVTSITTSSVINHVLHAS-DSENPESFLLWVHFSAPQNCISSSGELGPANEYNARVDIEVDRPGTSHVIQSVALRARSGTPRVHAPKDLQMVSLQAALGQTAKQTLPLKNAGNIDVLLRLKGTDDNCCFSVRPKELTLKAGEEQYVEVSFTAQDTQKHRESLLTILVLPSGPQYEVMLKGELVHGVSRKVASTPAVLSQVDVPLILSNKQSITWGGVSLGRAVQQKLVLRNNSPTISQQLRLLIRGQDQDCFQLQSSFGPNERLTRNRELSIKPKEDVTVHLLFAPTRVASMLAKLEIKQSAACASQPGVKFTIPLSGYGGKSNVILENLRKHSDGYVATLRGVQSGHVS---KLCICVRNTGSRAAFVKVVSYSSLKDQALMDSAVFSLSPSQFILKERTQEVIEIAMKASCR---EQALCQSGAALLATVCLFCGDEVSRQQFRKLLQIKPDAGNKVLSVKSLLKSIPFDEMFLGEEQVLEACDLPLRPNEAQTFYGNMRKVMLSLFGTTEILDLEESDHMEPTRPSQQHTSESDSSSCSSLGSLSHYISNVSLDVLPVKGP---SFTPSEPALKKTEPNMENTWSIKPEKMVLTVPTNNSVADPRHVQIMNHSNRVLSFELYWPAHCLTITPQHGFIEPQSHLQILVSTNPSLAHKSSMLPWNGQIYIQCGDQQKSIKVQIQQDLAMDVSTPIHATDCSLCPLPPQTDTPTVPGQSPQSSSIQPQVEIKNRTLIFPPTVSGESSECYLEVENNG-GEMRWYLSSFAPPYVKDVDRSGGVYRATYTAFRCGKVSGILGTQESMKVQFTFLPRDQGDYAQFWDLECHPAAKPQHKSRVRFQLCGTGISTKQ----GSSVKQNCLPVEKEDRVKSRKRLESAGTKTESTAEMHRKGLYAPQSVYTFPATRVHSTSVLKVNFRNNSPSTHELKFISPEEPFYIKHSNYSLRSQHYINLPVQFVPDAAGQFSGTLHVQTDTDAKLAIELIGEALP--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VV79-1", "uniprot_id": "Q9VV79_DROME", "id": "Q9VV79-1", "name": "", "aln": "--------------------------------------------------MDSSSGSQGNGSFMDQNSLGILN------------------------------------------------------------------MDNLKVFGDLSSFSKSGRRSGTGRDSPAVHERLREERLRALETLEKPRPSRSSQAKSTALQMR---LSTNISELVTDDTID------------LNSSSSFALVTPATKGTNISFEP-----------------------------------------------------------------------------------------------------------------------------------AEITGRSTLCQAG----------------------KQRRREKPSLSVAEILKSS-----------------------------------------------FVEKARLLERKLQDASQAEASYHLSRGSSSSLSDSFNCSRSLPRT--------------------------------------------ADMSELSLNGGGGFSFGSASLAAEGQD---------------ESFAPAELMQSKLVLGEISWAQEFTAMPTATLSTQALKKIAAPTSEIETSVSNSVLAGDP-------------DFSLGNYFQTRSENIWNIVSNSS-------------PNRSRTNQPLLEPESNVTLDSVGEKTPQPDNKTYTKTDAITGSNLGRNLMRKMQQDRIETALKSRNGLAAKETKR-------------------PPSSSEILSLSAIDKALRDIDLNSDTS-TVEVVNHLWEHGRGNNYDDGENKEN----------------------------------QSSNSHAERTSCGSNKLTDTMSFTDSVLNSTDFR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HLQQSISRKPLSPLADHPQITISRADTDPVETEAEADIDEWPSTPVKEPSRRVRRTKISPRAASPS-------------------------------------------------SSDGVRPLTCTED---------------------------------------------ENDEEDEDKTPVNKKRVSIATMGLIPRKASSLSSTR------------------------------------------------------------------------------------------------------------------------------------------------------------LDGCDVAVASSTERDFG--------------------------------------ISPNLAKNLSPLSSPRS----------------------------------------------------------------CLSSPLLDSTTSSDRRQLMSGAARKANSSPAGSEASSTSGFTASG------------------------------------------------------------------------------RRGLGTSSVAVPRSISRCSNSSEFSHRDGKLLPLKVT-------------------------------------------------------------------------------------------------HTTLCWGSTKLRTDVRKSMQVKN-TADKRLVIRLGIQGPG---FQLVG--------TDSSTITLQAMECRSVVINFCPTVCGAAIGALSFYAPPGAHNSNQPGLEIPLYGYGGSASITINGLLKGPVGASFLTIGDVCELSAGPLSANLKFHNKGPLTAFVGISVDSTVLMKLRLS-EAFEVRPSRLILPPNSERCVQILFRPNREDLKNILKKTAQVLTLANMRIFCGDEPNRQRMRSLVQRMSSRQREKLTSPMLDS---IWGEFPDEQPVRNIGQLNEPPEFILDLVTVVRIIDVALTLNRDFDESSESSLMFLPEAD---------------ETVLFRTICVANSPTPTQSHLLEPVDELLEADTTTLTPVEQNWCVQPGLLEFGVG----CSPLATLSVTNSFCSRQLIEVTCNVPDLVRISPSECYVSPDGGHAEIDVRLLRSPRQDLLEREPLIVVSMENERISVPISFKF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .: : *:: : : . . . . . : . .. . : : . . : :: * . .:. :** *: ::. .: * : . . . : . : : ::. : . . .. . . : . * : . * :: .. *.* .. . : .: .: :*. : :. . * . :: . :***::* *** : : ... . ..* .*:. .. . . . : :*.. : . ..: : : . . . :* :*:* .*: : .:.:*.: :: * :: *.: .:: ::. * : . : :. * : .. : . : . ..* : . . . . . : .. : .. . . .* *.:** * .. * *: ::: . * . . .*. *:: * :: :*: .* * . *: . . : * * . : .*:. . : . : **** : : : **. * :.: ::* :. ::* *:* . **: . * . : : . * : : *.** .. :. *.: . : *** ****.:.: ::.: * . . . : . : .:*.*. :*** . : :. .: : *.:::* .::. : : .. * .: :* *** .**: * . .: *. : . : * .* : :* . : : : ::: :: * : . .. : * . *.:. .. *: * : * : : . : ..: * :*: . *. . . . : :. . : :.. * : : : .: ", "identical_positions": 106, "similar_positions": 336, "identity": "3.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-168", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NQE9-1", "uniprot_id": "HINT3_HUMAN", "id": "Q9NQE9-1", "name": "Adenosine 5'-monophosphoramidase HINT3", "aln": "MAEEQVNRSAGLAPDCEASATAETTVSSVGTCEAAGKSPEPKDYDSTCVFCRIAGRQDPGTELLHCENEDLICFKDIKPAATHHYLVVPKKHIGNCRTLRKDQVELVENMVTVGKTILERNNFTDFTNVRMGFHMPPFCSISHLHLHVLAPVDQLGFLSKLVYRVNSYWFITADH----------LIEKLRT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CPS6-1", "uniprot_id": "HINT3_MOUSE", "id": "Q9CPS6-1", "name": "Adenosine 5'-monophosphoramidase HINT3", "aln": "MAEKQAGLVG--EPDPEG--------SSPGTSESWN-------YDSNCVFCRVAAGQEPKTELFHCENEDLVCFKDIKPAALYHYLVVPKKHIGSCKDLNKDHIEMVESMVAAGKTMLERNNFTDFTDVRMGFHVPPFCSISHLHLHVIAPVKEFGFLSKLVYRQDSYWFVTVDY----------LLEKLRK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32T7V2-1", "uniprot_id": "A0AB32T7V2_DANRE", "id": "A0AB32T7V2-1", "name": "Adenosine 5'-monophosphoramidase HINT3", "aln": "MADAAN------TPTPES---------CIASHSDEE-------YDKKCIFCKILKG-EMGTELLHS-DETVSCFQDIHPGAPHHYLVVPSKHVGNCKSLSKEHVPLVEKMLETGKEILEKNNVTDLSDVRFGFHWPPFCSVTHLHLHVLAPVSQMGFMSRLIYRLNSYWFVTLQAGGRRGVANGSQAGSLRPRI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: * *. . .: . **..*:**:: : ***:*. :* : **:**:*.* :******.**:*.*: * *::: :**.*: .** :**:**.**:::**:*** *****::******:***.::**:*:*:** :****:* : .** ", "identical_positions": 75, "similar_positions": 51, "identity": "38.66%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-171", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N3F8-1", "uniprot_id": "MILK1_HUMAN", "id": "Q8N3F8-1", "name": "MICAL-like protein 1", "aln": "MAGPRGALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLAFEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCSPGQAGVSPPRKGLAPCSP-PSVAPTPVEPEDVAQGEELSSGSLSEQGTGQTPSSTCAACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEHCARLGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGHP--------------ESTPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLALHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLEPPAVPKSSSEPAVHAPGTP---GNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSGATPTPLLLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVRPPAPGHGFPLIKRKVQADQYIPEEDIHGEMDTIERRLDALEHRGVLLEEKLRGGLNEGREDDMLVDWFKLIHEKHLLVRRESELIYVFKQQNLEQRQADVEYELRCLLNKPEKDWTEEDRAREKVLMQELVTLIEQRNAIINCLDEDRQREEEEDKMLEAMIKKKEFQREAEPEGKK-KGKFKTMKMLKLLGNKRDAKSKSPRDKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BGT6-1", "uniprot_id": "MILK1_MOUSE", "id": "Q8BGT6-1", "name": "MICAL-like protein 1", "aln": "MAGPRGALLAWCRRQCEGYRGVDIRDLSSSFRDGLAFCAILHRHRPDLLDFQSLSKENVFENNRLAFEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFTSSGQAAASPPKPGKDPAPPSPTSTSPAVQPGEEAQGDDLSPDSLSEQGKQQPPSSACAACGQRVHLVQRYLAEGRLYHRHCFRCRQCSSTLVPGSYSSGPEEGTFVCAERCTRLGPGSRSGTR-----LLSQQRQQPAAAEAKDAEDNDPSLSVAAVAEADRLQASSEVQFHTPTKPPLPSKPQELASPPGGRPTPAPRKASESSALTPPTPRPRSSLQQDGTVEQSVSSGLVNGRLQEPPVPKPRGTPKLSERMAAPRKDPPWITLVQTEPKKKPAPQPPSSGPGPLSQAYRQVEDGGLEEQTQKSSGTEPEPKPYNPFEEEEEEEGEPAPPVPSPSLAPPVPSPSPAPPVPSPAPAPSEATPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLAIHASRLSHSEPPSATPSPALSVESLSSESSSHTANAEPLEPPAVPKSSSDPAVHVPGTPGTSGNSVTPSANSSLSSSGELGQPSGEQMLQA------RTKGSAGTHSTKPFSGATPTPFLLAGDRNPAPPVGSASPQLQIKSSCKENPFNRKPSPSASPTVRKATKGAKPVRPPAPGHGFPLIKRKVQADQYIPEEDIYGEMDNIERQLDALEHSGVLLEEKLRGGANEGSEDDMLVDWFKLIHEKHLLVRRESELIYVFKQQNLEQRQADVEFELRCLLNKPEKDWTDEDRAREKVLMQELMTLIEQRDAIVNCLDEDRQREEEEDKMLETMIKKKDFQREAESDSKK-KGKFKTIKVLKFLGNKREAKSKAPGDKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B5U0-1", "uniprot_id": "A0ACD6B5U0_DANRE", "id": "A0ACD6B5U0-1", "name": "", "aln": "-MCSVFSLQDWCRGVCEGYSDVQITDMSSSFTDGLAFCAIIHKHRPDLLDFHSLSKHNAGENMRLAFSVAERELGVPALLDPDELLCE-EPDLLSIITYVSQLYCVFSGR-------------------SDDTQKNHMEDEPHRTRANTWLFSSDVIRSSDRSVCRVCHTHVHLIQRILVKGRLYHRSCFRCSVCRRSLLPISFTEHSETGSLRCSKPAG----------------EHTDQHSHTETERERGEADGEIVEKMSEVCLSDSPGTDQQAVLLHDQQSQHQTDRSSGETDRNDGETEGDRGEADRNGGETDSKRVETDINGGETDRNREEADRICG---------------------------------------------ETEDRGETDRNRGETDQNGGETDEDVSDGRLSSS-----------------------------------------------------------SSESDVQTPPRPAPRKRAEPQDHPCLAPRSHDHPP----------------ENVLPQRAVPKDHPWLKLVNPGPWYHLPPVP---------------------------------------VYSRHRPPTFNPFQEVE------------------EEDKQRNSVSCETSVSHKPQTSCSAPSMHQAT----------AVHGFPLIKRKINLDTRVSEQQVCVEQQKLEERLQDLERRGVQLERDMR----TRSDQSLLVDWFFLVHQKSMLVRRDGELMYMLKQQRLEDDQADVELEIRRLFNKPELDWTEEDRGQEQQLMSRLLSIIQQRSDIISSLELDRQREQEEDEMLSTVIQRRELLTDTHSQLHKGRRRFKQLQIFQTSSRKKSSR--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* *** **** .*:* *:**** ********:*:********.****.*. ** ****.***:***:******::::. ** ***:***** * * . : . . : .: .. :*.: .. *.* .* :***:** *..****** **** * :*:* :: . .* *:: *:: . .:*:.: : :. .. . . . :* :. :. :. . .. : . * . * :: . . : * .:.:: .: .:. : * :.. * .: :.::.* * : * .. :. *. :* ***** : . : **..** . . * : * : .. * * * .* . . . . :* . . . : : . **: . :: :..::*: ::** . *********:: * :.*::: * :.:*.:*: **: ** **..:* ::.:***** *:*:* :****:.**:*::***.**: ***** *:* *:**** ***:***.:*: **..*:::*:**. *:..*: *****:***:**.::*::::: ::..: :* : :** ::::: ..*:.:: ", "identical_positions": 209, "similar_positions": 222, "identity": "23.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-18", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P34981-1", "uniprot_id": "TRFR_HUMAN", "id": "P34981-1", "name": "Thyrotropin-releasing hormone receptor", "aln": "MENETVSELNQTQLQPRAVVALEYQVVTILLVLIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITDSIYG-SWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSLYCMLWFFLLDLNISTYKDAIVISCGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTHQNTNLNVNTSNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKPANYSVALNYSVIKES------DHFSTELDDIT--VTDTYLSATKVSFDDTCLASEVSFSQS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P21761-1", "uniprot_id": "TRHR_MOUSE", "id": "P21761-1", "name": "Thyrotropin-releasing hormone receptor", "aln": "MENDTVSEMNQTELQPQAAVALEYQVVTILLVVIICGLGIVGNIMVVLVVMRTKHMRTPTNCYLVSLAVADLMVLVAAGLPNITDSIYG-SWVYGYVGCLCITYLQYLGINASSCSITAFTIERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKNAVVVSCGYKISRNYYSPIYLMDFGVFYVVPMILATVLYGFIARILFLNPIPSDPKENSKMWKNDSIHQNKNLNLNATNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENWFLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKAANYSVALNYSVIKES------DRFSTELEDIT--VTDTYVSTTKVSFDDTCLASEN-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B6K5-1", "uniprot_id": "A0ACD6B6K5_DANRE", "id": "A0ACD6B6K5-1", "name": "Thyrotropin-releasing hormone receptor", "aln": "MENGTFSNGTWTDNS------VEYKVVSILLVILICGVGIVGNVMVILVVLTTKHMRTPTNCYLVSLAVADLMVLTAAGLPNITEILFGGQWVYGYAGCLSITYFQYLGINASSCSITAFTIERYIAICHPIKAQFMCTLSRAKKIIVLVWVLTSLYCVMWFYLLDTREKVYDNAVLVTCGYKVSRELYLPIYFTDYAVFYVIPLLLATVLYGLIARILFLNPLPSDPKESRRNWKKESSVHG-----NSRSSSNSTTVASRRQVTKMLAVVVILFALLWMPYRTLVVVNSFLKEAYLDTCFLLFCRLCIYMNSAINPIIYNAMSQKFRAAFHKLCHCRPQRSEKPPAYSVALTYSVIKETSNGESPDHYTTELDDIRGAAEELLPERKRLCFKEPAKDTLATA---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *.*: . *: . :**:**:****::***:*****:**:***: ***********************.********: ::* .*****.***.***:*******************************:**:*******::**.:**:**::**:*** . ..*.:*::::****:**: * ***: *:.****:*::*******:*********:******. : **::* :. *: . . .:**:**:******************************...: :. ******:***:******:*** *********:***:*: : :**.. *****.******: *:::***:** . : . .::.*.:.. : ", "identical_positions": 250, "similar_positions": 98, "identity": "61.43%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-181", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AYP3-1", "uniprot_id": "TTC29_RAT", "id": "Q6AYP3-1", "name": "Tetratricopeptide repeat protein 29", "aln": "MATFPPLSMTRTKLAVLARQKLPCSSKSIPRAQLIKEKDDIDYYLEQNIKGLSKEEVAAHRNSYKKSICVDMLRDGFHKSFTELFSLMEQWDKLREAAQARSLFWLQRPLEDQPDKLDNFYHYLTKAEAAERKGYYEEVYNNLYALACYFDNSEDKWVRNHFYERCFKIAQLIKVDGGKKEAEAEAHMGLLYEEEGELLKAAEHYEAFHELTQGRLWKDATGQFLNLIACESLVRTYRLLSDRMLQNRDYKQAIKILIKASEIAREGNDRSMEGEASYYLGLAHLASGEYETALSVLDRYSEISTSLDDELSLGRAYEAMAKVLQSQGEMTEAIKYLEKFVVIARNNFKSLDVIQACTMLGDIYNEKGQYNKASDYFQQAFSTAMEVTKTTLMDETKVHYGIARAHQMMLTMNGYIESADMNSLNCLLSWKETRTQVEYDPILGEARKATEDNIYQFPDAQEETRRSPENQ----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80VM3-1", "uniprot_id": "TTC29_MOUSE", "id": "Q80VM3-1", "name": "Tetratricopeptide repeat protein 29", "aln": "MATFPPLPMTHTRLAILARQKLPCSSKKIPRAQLIKEKEDIDYYLEQNFKGLSKEEVAAHRNSYKKSICVDMLRDGFHKSFTELFALMEQWDKLPEAAKAQSLFWQQRPLEDQPDKLDNFYHYLTRAEAAERKGYYEEVYNNLYALACYFDNSEDKWVRNHFYERCFNIAQLIKADGGKKEAEAESHMGLLFEEEGELLKAAEHYEAFHELTHGRLWKDGTGQLLNLVACESLVRTYRLLSDRMLENKDYKQAIKILIKASEIAREGNDRSMEGEASYYLGLAHLASGEYETALTVLNRYSEISTSLDDDHGLGRAYEAIAKALQSQGETTEAINYLEKFVTIARNNLQSLDMIRACTMLGDIYNEKGQYSKASEYFQQAFSTAMELMKTALMDETKVHYGIARAHQMMLAMKGYIESADSNGLNCLLSWKETRTQIEYDPILGESRRATEDNIYQLPDAEEETRRSPENQ----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NA56-1", "uniprot_id": "TTC29_HUMAN", "id": "Q8NA56-1", "name": "Tetratricopeptide repeat protein 29", "aln": "MTTLPPLPMTRPKLTALARQKLPCSSRKIPRSQLIKEKDDIDHYLEVNFKGLSKEEVAAYRNSYKKNICVDMLRDGYHKSFTELFALMERWDALREAARVRSLFWLQKPLEEQPDKLDYLYHYLTRAEDAERKESFEDVHNNLYALACYFNNSEDKWVRNHFYERCFKIAQLIKIDCGKKEAEAHMHMGLLYEEDGQLLEAAEHYEAFHQLTQGRIWKDETGRSLNLLACESLLRTYRLLSDKMLENKEYKQAIKILIKASEIAKEGSDKKMEAEASYYLGLAHLAAEEYETALTVLDTYCKISTDLDDDLSLGRGYEAIAKVLQSQGEMTEAIKYLKKFVKIARNNFQSLDLVRASTMLGDIYNEKGYYNKASECFQQAFDTTVELMSMPLMDETKVHYGIAKAHQMMLTVNNYIESADLTSLNYLLSWKESRGNIEPDPVTEEFRGSTVEAVSQNSERLEELSRFPGDQKNET", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YTI4-1", "uniprot_id": "A0A8M6YTI4_DANRE", "id": "A0A8M6YTI4-1", "name": "Tetratricopeptide repeat protein 29", "aln": "MSSKTRFSMIHS---PQKTNRTTPTSKSFPRC----NKKNSGSPVGEEPNKMTETEIAQIGKPLRQNICVEMLRDGFPHSFKELFALLQRWDEA----------------DDDPHKLQTLQLHLTRAEAAERAGKYDEAYENHMLLARFFT--EDKWMKHHFLELALRSARKVIMDSGKREAEARSLVGQAYLEKGDLELAQEHLEVFYQLTAGRTWQDSNGRMQHSRSCEELQTVYTLMAQRSLQDQQYEQAIKMSRKAYTIAKESGDRALEGEAAYRLGLAYQSTGDQKIAMKFLSSYMEIALTLEDTDSLGRAHEAMAKCLESEGKITEAIELWEKYVETCKSSKQDQNLERAYMSLGHILKSQKRYGEARVYFERALELACLEGCPRRVQEAQVYVGITRALSTFPAYMKLIQDQN---LDALLAWKDRR----------EDRFSSAASSEPESTAQSNTVVP--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: . :.* :. :: . :*:.:**. :*.: . : : : ::: *:* :. ::.***:*****: :**.***:*:::** :::*.**: : :**:** *** :::.::* ** :* ****:::** * .:. *: : * **:****. :* : *.*:* * ** *.*::** ** *:* .*: : :**.* .* *:::: *::::*:****: ** **:*..*: :*.**:* ****: :: : : *:..*. * :*: *:* .***.:**:** *:*:*: ****: :*:* .:.. :. :: :* **.* :.: *.:* *::*:. : ::*::*: **::* . : : *:. : *: **:**: * * * :: . .: ", "identical_positions": 138, "similar_positions": 158, "identity": "29.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-182", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AI05-1", "uniprot_id": "A0A8I6AI05_RAT", "id": "A0A8I6AI05-1", "name": "", "aln": "MDATALHDDTSASSVPLSEACNHAVLACSPGIPEEHYVSEAIEDAPSYRGHRDACTITDVCNSTNLPEVEIISLLEEQ----LPHYKLRADTIYGYDHDDWLHTPLIS-------PDANID--LTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEACQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKSCAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMP--TSRRYHSLG---------LFPMDSLAAEIEG-TMRKELQLEEPESPDITHQ-----------------------------------KRVFETVRNVNQVVKQRSLTPSPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDVSHVVLDNKTNSILLETEAADLGNEEHNKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLRELAE-KGELH------SGSLTPTESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGILDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHIS-------LAGLATS----------------------------TTIQHMETSAHHPGKCMSQTNSTFTFTTCR---ILHPSDELTRVTPSLNSAP-----APSCSSTSHLKSTPVATPCTP-------------RRLSLAESFTNVRESTTTMSTSLGLVWLLKERGISAAVYDPQSWDRAGRGSLLHSYTPRMA--------VIPSTPPNSPMQTPSASPPS-FEFKCTSPPYNNFLASKPASSILREVR--EKKHVRSSESQTDVSVSNLN--------LVDKVRRFGVARVVNSGRAHI--PTLTEDQGPLLCGPTGPAHALVPGGLVPEGLPLGCP------------SGIRRNRSFPTMVGSSVQMRAPVILTSGILMGAKLPKQTSLR-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PD31-1", "uniprot_id": "TRAK1_MOUSE", "id": "Q6PD31-1", "name": "Trafficking kinesin-binding protein 1", "aln": "-MALAIQLRQPSRAQPLPG------------------LSHTLAGTDS----------CDVCNSTNLPEVEIISLLEEQ----LPHYKLRADTIYGYDHDDWLHTPLIS-------PDANID--LTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEACQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKSCAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMP--TSRRYHSLG---------LFPMDSLAAEIEG-TMRKELQLEELESPDITHQ-----------------------------------KRVFETVRNVNQVVKQRSLTPSPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDVSNVVLDNKTNSILLETEAADLGNEDHNKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLRELAE-KGELH------SGSLTPTESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGILDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHIS-------LAGLATS----------------------------TPIQHPETSAHHPGKCMSQTNSTFTFTTCR---ILHPSDELTRVTPSLNSAP-----APACSSTSHLKSTPVATPCTP-------------RRLSLAESFTNVRESTTTMSTSLGLVWLLKERGISAAVYDPQSWDRAGRGSLLHSYTPRMA--------VIPSTPPNSPMQTPSASPPS-FEFKCTSPPYNNFLASKPASSILREVR--EKRPVRSSESQTDVSVSNLN--------LVDKVRRFGVARVVNSGRARI--PTLTEEQGPLLCGPTGPAQALVPGGLVPEGLPLGCP------------SGIRRNRSFPTMVGSSVQMRAPVILTSGILMGAKLPKQTSLR-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPV9-1", "uniprot_id": "TRAK1_HUMAN", "id": "Q9UPV9-1", "name": "Trafficking kinesin-binding protein 1", "aln": "-MALVFQFGQPVRAQPLPG------------------LCHGKLIRTN---------ACDVCNSTDLPEVEIISLLEEQ----LPHYKLRADTIYGYDHDDWLHTPLIS-------PDANID--LTTEQIEETLKYFLLCAERVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKTLTERNELLEEQVEHIREEVSQLRHELSMKDELLQFYTSAAEESEPESVCSTPLKRNESSSSVQNYFHLDSLQKKLKDLEEENVVLRSEASQLKTETITYEEKEQQLVNDCVKELRDANVQIASISEELAKKTEDAARQQEEITHLLSQIVDLQKKAKACAVENEELVQHLGAAKDAQRQLTAELRELEDKYAECMEMLHEAQEELKNLRNKTMPNTTSRRYHSLG---------LFPMDSLAAEIEG-TMRKELQLEEAESPDITHQ-----------------------------------KRVFETVRNINQVVKQRSLTPSPMNIPGSNQSSAMNSLLSSCVSTPRSSFYGSDIGNVVLDNKTNSIILETEAADLGNDERSKKPGTPGTPGSHDLETALRRLSLRRENYLSERRFFEEEQERKLQELAE-KGELR------SGSLTPTESIMSLGTHSRFSEFTGFSGMSFSSRSYLPEKLQIVKPLEGSATLHHWQQLAQPHLGGILDPRPGVVTKGFRTLDVDLDEVYCLNDFEEDDTGDHIS-------LPRLATS----------------------------TPVQHPETSAHHPGKCMSQTNSTFTFTTCR---ILHPSDELTRVTPSLNSAP-----TPACGSTSHLKSTPVATPCTP-------------RRLSLAESFTNTRESTTTMSTSLGLVWLLKERGISAAVYDPQSWDRAGRGSLLHSYTPKMA--------VIPSTPPNSPMQTPTSSPPS-FEFKCTSPPYDNFLASKPASSILREVR--EKN-VRSSESQTDVSVSNLN--------LVDKVRRFGVAKVVNSGRAHV--PTLTEEQGPLLCGPPGPAPALVPRGLVPEGLPLRCPTVTSAIGGLQLNSGIRRNRSFPTMVGSSMQMKAPVTLTSGILMGAKLSKQTSLR-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B1F5-1", "uniprot_id": "A0A8M3B1F5_DANRE", "id": "A0A8M3B1F5-1", "name": "", "aln": "---------------------------------------------------------MNVCNSTDLPEVEIISLLEEQ----LPHYKLRADTIYGYDHDDWLHTPLIS-------PDVNLD--LTTEQIEETLKYFLLCADRVGQMTKTYNDIDAVTRLLEEKERDLELAARIGQSLLKKNKSLTERNTFLEEQLEHIREEVSQLRHDLLMKDELLQFYTSAAEESDGESASTTPIHRNDSSFTVPNYLPLDSLQKKLKDLEEENIVLRSEANHLETETISYEEKEQQLVNDCVKELRDANIQISTIAEELAKKTEDASRQQEEITHLLSQIVDLQKKAKSYALENEELTQHLGAAKDAQRALTAELRELEDKYAECMEMLHEAQEELKNFRNKTVPLSTPRRFHSLG---------LFPMDSLAAEIEG-TMRKEIQMSDPDVEEQRLQP----------------------------------KRVFETVRNVNQSVRQRSMGPSPMNIPGSNQTSSMNSRRSSCMSTPRSSMYGGDG--VEIDNRTNSLLLETQSPQDGSNDSNRKPGTPGTPGSHDLQAALRRLSLRRDNYLSERRFFEEERERKLNALAEDKSQFYEDSEDGGGPLTPADSIMSLGLNSVFSIYS--------SRSYLPEKLQIVKPLEGSATLHAWQQLAQPHLGGLLDPRPGVVTKGFRPLELELEEVYQFTDLEEDEPGQHSQSSISSSCISSLPCSPAARRSRGNPE------------QEDQQSPAQEEGSSVHFPGKCMSHSSSTYTFTTCR---ILHPSDELTRVTPSLLSGPS---LASCVMSSSSLRSTPVSTPCTP-------------RRLSLAESFTNLRDSTKTTSTSLGLVRLLQERGISAAVYNPLSWDRADQALPADPLTPHTASPFHTGPDTLPSTPPNSPSKSKPSSPVLPVDYSPSDPPYETFLASRPASSILKEVRGADERAQTDMQCQTEVSVQNLR--------LVDKLKKFSLAPRTLTPGIGR--PSLGFGAHAVVTSPIGGLPVLN--------------------------SGMRRNRSYPAMVGASMAMKGPGPPSEDLLLPSGSPRQTSLKEK-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q960V3-1", "uniprot_id": "MILT_DROME", "id": "Q960V3-1", "name": "Trafficking kinesin-binding protein milt", "aln": "--MTHVNNGEVMEKEMEPTGERERDRETAAGSGVHHRFLASASERDANSGNALEAAATKTKTGTTITNLEDLAFEACQNWSDLHQDFFITDDELEYEDELSLGSSIGGNIATTTTADAAVEGLITGEHQNEQLLMEVLCGNRVSQMTRAYDDIEAVTRLLEEKEKDLELTVQIGKELLTQNNALEARVADLETDLKASNDDRAQLVHELHKKNELISVLTNDADDG-----------TDTDTPTMSKSITLDLLQRKVNSLLDENKSLKCEATQLAHQTDEVEEHERQLMADISAQLNDANSQYDNLSLELERQREENRLQHEQIVNLTARLAEAEMRLHQLTQDNDEHLSLLHVTKENQNALALELVEFKQRYEEVLALLHSAQDQLKQQRKRSQPQARSSFLGGLGTSGAGMGGSLFPPDSLHCELMESSLYSENSLDSGISGDSQRSADRISRMMMHMPSGGMSSSTMGGSVYAGAGNVPPYKRVFDTVRCAGKSGNYMDSGNVSMTQLGAMSMSSSSGPRMASMAYPAGSYYRGGSNQSLGVKTLSSESLNSQSDD---GYPAQPSGVPGAPGAKELEAALKRLTPAEVLARRAMLSYAPAGTYNYDEPMG-HGTGNVRNSDLPLGVRTPDSIMSTGS-SGMSGSTNHMSASMTHQWRLPEKLQIIKPMEGSQTLHHWSRLATPTLSGLLDERPGVTIRGGRGLDDLGMQIYTLSDVEEDVSDDLPGKQFEAPGCTFTYTNSMVMHPDDGFVNDLSFLSQSQMSSRMASTSTSRQPSCPATPRAGLSRKNSCSTFSVNLGLAGMLNERGIKAVTPSALNTPAGPNFSPTVTPCNSPEGSPPRAQSPEPLFGLLSCGADLIRRKIVGDQHQQQQQKQRSSLSKQQQQKIMLSHLERRALRSLNLIEKVESIGLENIISAQRGLGSGIANRSSSPLSSGSLQSLHTSSNSIVDDIHFDRAQIKGVLHRGLKSPTPATASTSAAAAASGPGISTSSSTSAYNSDDSDDQGLVMKIKPSKSATPTTTGAAQSQPSSATTSNGTASETRLKQMQRQKSRRQLKNGMANQRPDLGTISG---AGGGGRVRPDLGKVADSGSSSKLSTKRSEAKPAEEEEATPQTITQAFVGSVSSLLFGRKGGWL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. ..* :.::* ::: * * : : :* *:.: * :.: . .*. :: :* *: :* * :**.:**.***::*:**:**********:****:.:**:.**.:*::* * ** ::: .:: :** *:* *:**:.. *. *::. : .: :: : : ** **:*::.* :** *:.** :* :* **:*:**: * :*.*** * .:: ** :: *: *:*:*.:* :::.: : : : : :*:* . * .:*: *. *: ** *::::* * : :**.**::**: *::: * . .** *** *** .*: :: .* .:.. : . ****:*** .: . . .*. *: . *: .. :.:: * .* * .. : .* *:::: : : .*.**:**:::*::**:**: . : : :. : ..:**** * * :* : : *******:**:*** *** *.:** * *.*:** ****. :* * *: ::* :.*.*** ..: . . :. .. :. * :*:..* **:. : . :. **** . * :. . . ..:* : .. ** :.:.. : ::. : :. :: .: *: . ::. . :.: . .. ...* . .:* : . . .* *. . . .*. *.. . ** *:: * . : .: . .* * . . :..:. : . :. . :: ", "identical_positions": 207, "similar_positions": 299, "identity": "18.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-183", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59862-1", "uniprot_id": "CAD26_MOUSE", "id": "P59862-1", "name": "Cadherin-like protein 26", "aln": "--MDTRGCAWLLLLLSLP-----------------------QGQSHQPLHRSKRRWVLTTLELQEEDPGPFPKLVGELFNNMSNNVSLIYLIRGPGVDEFPEIGLFSIEDHQSGKIYVHRPVDREVTPSFMVHFDAVDRSTGKVVDESLIFNIRIRDVNDHAPQFPEKEFNISVKESQAAGQPIFQLLTVDLDQENTPNSQVLYFLVSQTPLLR--ESGFRIDLISGEVRLSGCLHYETAPLFTLIVRASDCGEP-SLTSTATIHVSVEDSNNHMPTFMEDRYEIRISEGQVEQGVLYLPVQDGDSPFTPAWRTQFNIWDGNEEGHFDIVTDPETNQGLLSIIKPLDYESQVAHSLVVVVENQEQLFVCTEGQLQP----------------LRKAMASTMVSVQVLDTNDPPAFHPQSFIVSEEDGAWPAIQLGYFNATDPD-RADSQIRYKLVHDPENWVTVDEKSGVVTTKKQIDRESPHVNDSFYTIIVHAVDNGLPPLTGTGTLMLFLSDVNDNAPTLRPHSRHLEVCESAGSQPLLIEAEDADLDPYADPFTFDLDNAQGDVEETWMLRTKQGEGHSAELTMLRSVPPGDYLVPLFIADRQGLAQKQTVHVRICSCRSGSECEEPSD--TWLLWWALSPVGAALMVLSAALLCLLRCSCTFGPKRLRGFIPSDSGHQTLIVYNEESKVPSAQ-----------------------------------------------------------GCDTFFEPRGVKTLLSSTPVYLDRMVPRQQPLQLLEGRVVEAWSQKLQSIDVLEGDT-GYLPHVYREEGECEGAETLSSLTFLEQDLSPKLLGCSGSKSTPSEAMCFTSRVPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IXH8-4", "uniprot_id": "CAD26_HUMAN", "id": "Q8IXH8-4", "name": "Cadherin-like protein 26", "aln": "MAMRSGRHPSLLLLLVLLLWLLQVSIIDSVQQETDDLTKQTKEKIYQPLRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLK--ESGFRVDRLSGEIRLSGCLDYETAPQFTLLIRARDCGEP-SLSSTTTVHVDVQEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDYETRPAQSLIIVVENEERLVFCERGKLQP----------------PRKAAASATVSVQVTDANDPPAFHPQSFIVNKEEGARPGTLLGTFNAMDP----DSQIRYELVHDPANWVSVDKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVHEPLHIEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWG--QSVELLTLRSLPRGNYLVPLFIGDKQGLSQKQTVHVRICPCASGLTCVELADAEVGLHVGALFPVCAAFVALAVALLFLLRCYFVLEPKRHGCSVSNDEGHQTLVMYNAESKGTSAQTWSDVEGQRPALLICTAAAGPTQGVKDLEEVPPSAASQSAQARCALG----------SWGYGKPFEPRSVKNIHS-TPAYPDATMHR-QLLAPVEGRMAETLNQKLHVANVLEDDP-GYLPHVYSEEGECGGAPSLSSLASLEQELQPDLLDSLGSKATPFEEIYSESGVPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A8N0-1", "uniprot_id": "A0AB13A8N0_DANRE", "id": "A0AB13A8N0-1", "name": "", "aln": "--MRTPAFSVLLLLLLSWS---------------------VCSWADGGKIRQKRMWIIESFAIEEESPGPFPYKIGNIHAEKAY--LLKFELQGEGVDKEPKN-LLTINDKAD--VYVHRKVDYESGQNILKLMFEAKNKSNNEVDIRLGVEIRILDINDHAPAFQKSVYEVTVDESQAQGTEVLTVLAHDNDNPTTSNGTFTYTIKSVTPKTENVEFYIRQHKESGSIYFKGCLDYEKAQKYTILVEAKDNGDKKQLSSTSTVIINIQDGNNNLPEFTGKTGPGKVKERETGVEVLRLQVTDKDKPGSKAWIAKYTIN-GDKENLFKIETDPVTNEGILTVVKAMDYEEQTHQNISIIVQNEVPYFSCKVKKQVPNAMWELDKIPQNPGASVASLYKTMQATIHVDDINDPPVFIPPVKNVPVLENTAIGTSLTTFIAKDTDGSHANTFKFVKGEDLDNWVTVDPVTGQVTTAKVLDRESPFVINDTYKVIVYAVDDGVPQLTGTGTLFIHVNDENDNVPILEMN--RIDFCLNAEPTMANITAKDLDLPPYSSPFYYELL---GDVKNKWRIDPIQG--NTVTLVKEKDVFSGHQLLQIKISDQQGLYSIQNLSVTVCDCSVNSDCHVRMVSKARMGPTAALLVLLAILILIVMGLLALLISCKQEKK----MIANDDAIGCLITTNTENPGTDCTVPFSIGVDKPDSANMHSSMHVSTNVKSSQNITSQTVIQKSQHAVSQAPQLLYDGQAFERSAYRSSTRRSYRKNFQRASIRSSFRSNYKVNTSYFGENLAVLINQKVLALQKREDELGVYEPHCYADEGKPTASSELDAISISEDDFHPDMLKTLDNRFSQLATISRPDLMRR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . ***** *.** *:: :: ::**.***** :*::. : : * : : * ***: *: *::::*: . :**** ** * .: : ....:.: ** * .:*** *:***** * :. ::::*.*.*: * :: :*: * *: .*.*. . * : * ** . * :* . **.: :.***.**.* :*:::.* * *: .*:**:*: :.:::.**: * * . :: * .. ** * * * *.* : ** :::.* *::*. *.* *** **:*:*.::*.:*** : :.: ::*:*: . * : * . : .:::* * ****.* * * :.: . * * * *. . ::: .* ***:** :* * * : :*****.* :. * :*::***:*.* *.****::.:.* ***.* *. . ::.* .* * *:* ** *::.** ::* *:.::.* : * ::. * :.: *. *: : *.*:*** . *.: * :* * . * . : * * *:: * . * * * :..*.. *: * *. ... . *. :. . :. . . .:. .**: : *.: * ** * :**: .: *.::: *::: *.:* ..: : : . : ", "identical_positions": 209, "similar_positions": 239, "identity": "24.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-189", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96NA8-1", "uniprot_id": "TSNA1_HUMAN", "id": "Q96NA8-1", "name": "t-SNARE domain-containing protein 1", "aln": "MSYGSIARGGGLGSRGPFGGPSRQGCQPLECARCWTEYGIRHFPCPSPESKLQNRCVGKDGEGDLGPAGTPIVPRARKRGPGVAPEGSRMPEPTSSPTIGPRKDSAAGPHGRMAGPSTTRAKKRKPNFCPQETEVLVSKVSKHHQLLFGTGLLKAEPTRRYRVWSRILQAVNALGYCRRDVVDLKHKWRDLRAVVRRKLGDLRKAAHGPSPGSGKPQALALTPVEQVVAKTFSCQALPSEGFSLEPPRATQVDPCNLQELFQEMSANVFRINSSVTSLERSLQSLGTPSDTQELRDSLHT-AQQETNKTIAASASSVKQMAELLRSSCPQERLQQER---PQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLPMAQRGSKQSPQAPFAELADDEKVFNGSDNMWQG------QEQALLPDITEEDLEAIRLREEAILQMESNLLDVNQIIKDLASMVSEQGEAVDSIEASLEAASSHAEAARQLLAGASRHQ---------------LQRHKIKCCFLSAGVTALLVIIIIIATSVRK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T5F7-1", "uniprot_id": "A0AB32T5F7_DANRE", "id": "A0AB32T5F7-1", "name": "", "aln": "MSYGSIDAG-SFGSRNPFGGPTRQGYQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVATQVSPSELQDVFQETSSNIFQINANVVTLEKNLQSLGTSRDTAELRQSLHS-TQQQTNKVITSTSQLVKQLTDIISGSSRQDRLR--------LTRLKTELSDSVQRYGELQKKIADRSRALLPPAQKDRKQSVQTPFSELVEEGPLF-GAGESTEG------DVQAFLSEISEEDVEILRQREEALLQIERDMLDVNQIMKDLASMVHEQGDTIDSIEDYIQTTSSHVETANQELAKASHYQDTGQLTLLEASSNQRRQLRRRKCFLLIGGLLLLTLLIIIIAVSARK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VU45-1", "uniprot_id": "Q9VU45_DROME", "id": "Q9VU45-1", "name": "", "aln": "MSKALNNPGGNGGGGGPHRDYGAMADSTPEVS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FAAAGGSSGFSPTEFMSLSEDIGHNITAIHSSTKQLEKQLKLIGTSKEQPNLREKVHT-INTKCNARVQTTSQDLQRLQAVVRHGDRQQKLQ--------LEKLTREFHGVVEKYSNLQRRISSAMRQTLQQAQQFADQVVET--------------NARAELL------QQQRLEQAHLQQEHDMLDDRRRQVEQIESDIIDVNQIMTQLSGLVHDQGQQMDFIENSIEQTAANVEDGTSELAKAARSR---------------QSYRRKILILLVIAVIIGLIVTGVIVAKLNS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32854-1", "uniprot_id": "PEP12_YEAST", "id": "P32854-1", "name": "Syntaxin PEP12", "aln": "-----------MSEDEFFGGDNEAVWN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GSRFSDSPEFQTLKEEVAAELFEINGQISTLQQFTATLKSFIDRGDVSAKVVERINKRSVAKIEEIGGLIKKVNTSVKKMDAIEEASLDKTQIIAREKLVRDVSYSFQEFQGIQRQFTQVMKQVNERAKESLEASEMANDAALLDEEQRQNSSKSTRIPGSQIVIERDPINNEEFAYQQNLIEQRDQEISNIERGITELNEVFKDLGSVVQQQGVLVDNIEANIYTTSDNTQLASDELRKAMRYQ---------------KRTSRWRVYLLIVLLVMLLFIFLIMKL----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : .. :: : :: . :: *:.. *:: : : : :: .: : . : . :::: : :. :* :. .: : :*::::. : *:. . : : : : : : : * . : ::* .: ::*:::.:*..:* :** :* ** : :: :.: . . * * : : : :* : .: :: ", "identical_positions": 18, "similar_positions": 96, "identity": "3.35%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-19", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZAT9-1", "uniprot_id": "FAXC_RAT", "id": "D3ZAT9-1", "name": "Failed axon connections homolog", "aln": "--MHWGVGFASSRPCVVDLSWNQSISFFGWWAGSEEPFSFYGDIIAFPLQDYGGIMAG-LGSDPWWKKTLYLTGGALLAAAAYLLHELLVIRKQQELDS---KDAIILHQFARPNNGVPSLSPFCLKMETYLRMADLPYQNYFGGK--LSAQGKMPWIEYNNEKVSGTEFIIDFLEEKLGVNLNKNLGPHERAVSRAVTKMVEEHFYWTLAYC--QWVDNLNETRKM-LSLSGGGPFSNLLRWVVCHITKG----IVKREMHGHGIGRFSEEEIYMLMEKDMRSLAGLLGDKKYIMGPKLSTLDATVFGHLAQAMWTLPGTRP--ERLIKGELINLAMYCERIRRKFWPEWHHDDDNTIYESEESSEGSKTHTPMLDFSFYSRTETFEDEGAENSFSRTPDTDFTGHSLFDSDVDMDDYTEHEQCK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5TGI0-1", "uniprot_id": "FAXC_HUMAN", "id": "Q5TGI0-1", "name": "Failed axon connections homolog", "aln": "--MHWGVGFASSRPCVVDLSWNQSISFFGWWAGSEEPFSFYGDIIAFPLQDYGGIMAG-LGSDPWWKKTLYLTGGALLAAAAYLLHELLVIRKQQEIDS---KDAIILHQFARPNNGVPSLSPFCLKMETYLRMADLPYQNYFGGK--LSAQGKMPWIEYNHEKVSGTEFIIDFLEEKLGVNLNKNLGPHERAISRAVTKMVEEHFYWTLAYC--QWVDNLNETRKM-LSLSGGGPFSNLLRWVVCHITKG----IVKREMHGHGIGRFSEEEIYMLMEKDMRSLAGLLGDKKYIMGPKLSTLDATVFGHLAQAMWTLPGTRP--ERLIKGELINLAMYCERIRRKFWPEWHHDDDNTIYESEESSEGSKTHTPLLDFSFYSRTETFEDEGAENSFSRTPDTDFTGHSLFDSDVDMDDYTDHEQCK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UMF9-1", "uniprot_id": "FAXC_MOUSE", "id": "Q3UMF9-1", "name": "Failed axon connections homolog", "aln": "--MHWGVGFASSRPCVVDLSWNQSISFFGWWAGSEEPFSFYGDIIAFPLQDYGGIMAG-LGSDPWWKKTLYLTGGALLAAAAYLLHELLVIRKQQELDS---KDAIILHQFARPNNGVPSLSPFCLKMETYLRMADLPYQNYFGGK--LSAQGKMPWIEYNNEKVSGTEFIIDFLEEKLGVNLNKSLGPHERAVSRAVTKMVEEHFYWTLAYC--QWVDNLNETRKM-LSLSGGGPFSNLLRWVVCHITKG----IVKREMHGHGIGRFSEEEIYMLMEKDMRSLAGLLGDKKYIMGPKLSTLDATVFGHLAQAMWTLPGTRP--ERLIKGELINLAMYCERIRRKFWPEWHHDDDNTIYESEESSEGSKTHTPMLDFSFYSRTETFEDEGAENSFSRTPDTDFTGHSLFDSDVEMDDYTDHEQCK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8N7TB71-1", "uniprot_id": "A0A8N7TB71_DANRE", "id": "A0A8N7TB71-1", "name": "", "aln": "--MYWVAGFASSRSFVVDLGRNQSPSFG--LCGSDERHLFYGYIVAVPVQDFGGIMSG-LVSDSWWRKTLYITGGALLAAAAYLLHELLSIRKDQELDS---KDAIILHQFSRPKNGVPSLSPFCLKMETYLRMLDLPYQCYFDGS--LSAQGKMPWIEYNYEQVCGTEFIIEFLEEKLGMSLNKSLSAQEQAVAQAITTMVEEHLYWSIAYC--QWVDNVQETQRM-LDLPG--PLSDLLKWILCQLTGG----MVKREMYCHGIGSFTKDEVYSLMEKDMRTLATLLGDKKYIMGPKLSSVDATVFGHLAQAMWTLPGTRP--EQLIKGELINLAMYCERIRRKFWPEWFVDLEDFCYDSDNDTN-SGTPPCPLDLGLFSRTDTLEE--SDLSLPSHSNSELS-----DSDIEVDGSDGEQKVKG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q95RI5-1", "uniprot_id": "FAXC_DROME", "id": "Q95RI5-1", "name": "Failed axon connections", "aln": "MASEVAQIPAEETPAVAAAEKSEEPEKSAAPPADSAAAPAAAPAVEKAEDADGEKKDGEAGKQDKQQDGEEPKKDEAVAAPVATKSEAPPAQKFNVHKTNFEKDIIYLYQFSR-TPLLPSLSPYCLKVETWLRLVGLKYENVDHKMRFRSKKGQLPFIELNGEEIADSAIIIKELSSKYEKYLDSGLTAEQRNVSYATIAMLENHLIWIIFYWRAKYPDNVLKGYKVNLQHALGLRLPNSILNFFFKITFGRKWFQGTKKLKAHGIGVHSAEEIEEFGKDDLKVLSEMLDCKPFFFGDEPTTLDVVAFAVLSQLHYLSKDIAYPLRDYMTEKCPNLIGHVSRMKDKCFPDWDEICTKLDLNAHIPKPEPETKEGKEGGEQEKSNE--QEGTEGDKIEKELEKDKS-----NEKESTEENKEKEETK-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. . *. .:. . ... . : . : * * .: :. . . :**.. * :* : .: ** * *:**:* . :*****:***:**:**: .* *: * :*::*:** * *::..: :**. *..* *:..* ..:: :: * *:*:*: * : * :: **: : :: *. . :.: : .. ::* * .::: **** .: :*: : :.*:: *: :*. * :::* : :::*...*. *:* : . . :. : ** : .*:: * :*:* . ::. . . * . . .: :: .: :.: : :.. . : .:: * ", "identical_positions": 75, "similar_positions": 146, "identity": "17.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-193", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59862-1", "uniprot_id": "CAD26_MOUSE", "id": "P59862-1", "name": "Cadherin-like protein 26", "aln": "--MDTRGCAWLLLLLSLP-----------------------QGQSHQPLHRSKRRWVLTTLELQEEDPGPFPKLVGELFNNMSNNVSLIYLIRGPGVDEFPEIGLFSIEDHQSGKIYVHRPVDREVTPSFMVHFDAVDRSTGKVVDESLIFNIRIRDVNDHAPQFPEKEFNISVKESQAAGQPIFQLLTVDLDQENTPNSQVLYFLVSQTPLLRESGFRIDLIS---GEVRLSGCLHYETAPLFTLIVRASDCGEPSLTSTATIHVSVEDSNNHMPTFMEDRYEIRISEGQVEQGVLYLPVQDGDSPFTPAWRTQFNIWDGNEEGHFDIVTDPETNQGLLSIIKPLDYESQVAHSLVVVVENQEQLFVCTEGQ-LQPLRKAMASTMVSVQVLDTNDPPAFHPQSFIVSEEDGAWPAIQLGYFNATDPDRADSQIRYKLVHDPENWVTVDEKSGVVTTKKQIDRESPHVNDSFYTIIVHAVDNGLPPLTGTGTLMLFLSDVNDNAPTLRPHSRHLEVCESAGSQPLLIEAEDADLDPYADPFTFDLDNAQGDVEETWMLRTKQGEGHSAELTMLRSVPPGDYLVPLFIADRQGLAQKQTVHVRICSCRSGSECEEPSD--TWLLWWALSPVGAALMVLSAALLCLLRCSCTFGPKRLRGFIPSDSGHQTLIVYNEESKVPSAQ-------------------------------------------------------------GCDTFFEPRGVKTLLSSTPVYLDRMVPRQQPLQLLEGRVVEAWSQKLQSIDVLE-GDTGYLPHVYREEGECEGAETLSSLTFLEQDLSPKLLGCSGSKSTPSEAMCFTSRVPS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IXH8-4", "uniprot_id": "CAD26_HUMAN", "id": "Q8IXH8-4", "name": "Cadherin-like protein 26", "aln": "MAMRSGRHPSLLLLLVLLLWLLQVSIIDSVQQETDDLTKQTKEKIYQPLRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLKESGFRVDRLS---GEIRLSGCLDYETAPQFTLLIRARDCGEPSLSSTTTVHVDVQEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDYETRPAQSLIIVVENEERLVFCERGK-LQPPRKAAASATVSVQVTDANDPPAFHPQSFIVNKEEGARPGTLLGTFNAMDP---DSQIRYELVHDPANWVSVDKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVHEPLHIEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWG--QSVELLTLRSLPRGNYLVPLFIGDKQGLSQKQTVHVRICPCASGLTCVELADAEVGLHVGALFPVCAAFVALAVALLFLLRCYFVLEPKRHGCSVSNDEGHQTLVMYNAESKGTSAQTWSDVEGQRPALLICTAAAGPTQGVKDLEEVPPSAASQSAQARC------------ALGSWGYGKPFEPRSVKNIHS-TPAYPDATMHR-QLLAPVEGRMAETLNQKLHVANVLE-DDPGYLPHVYSEEGECGGAPSLSSLASLEQELQPDLLDSLGSKATPFEEIYSESGVPS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F370-1", "uniprot_id": "E7F370_DANRE", "id": "E7F370-1", "name": "Cadherin-like protein 26", "aln": "-MMKAAVFLLLFTLGELSASYTN--------------DTSSRQKRDAVLIRTKRRWVLSTIDLEENMRGPFPLEVTQMFNDKKQ-ENVKFRISGEGVTT-PPIGLFSINEN-TGSVFVHRAIDREINPIFHVDFDVLDKDTGAPLDRTLSFNVEIKDLNDNAPLFTPTTIPASVPENALEGPIQATLQAHDNDQKDTYNSEFTMRVVSQDPAVPVFSLRDMPQTNKYKQLAFSGCFDFDKAKTYKVLIEAKDKGTPPMSSTATVIVNITDSNTHQPEFSSTTYNAEVMEMESNKEILRINITDKDTPNTPASRAVFSILKGNEEGYYRIVTDPKTNQGVLSVIKGKNFEKTEITQLEIAVENEEKIFQCVDGKRTSAPPPKPQTTKVAVKVIDLNDPPVFKKVIEKVYRNENGKPGDVLFTPDIKDEDSDVNNIRYELVKDPAKWVSVDPKTGKITTVQTMDRESPFVRNGTYTVVVQAIDDGQPPATGTCTVVVYLGDLNDNAPYLPSNK---TVMCANNMNRVRVFPADDDAPPFSGPFTFSLGDEE--MKKLWKLDPTTG--LNSSLISLTSLPYGNYTVPLKIQDQQALQSDVVMFVSVCECSSPHTCRGLLPLSSRLGPAAIGLMIAGLLLLALLLLFSFLCDCNSKNFQHIPLSLQDEGNQTLVKYNDEGGGSVFRPESMLVSNLAMKESIKVASAPAVDYVATDGFRRSENGTMRSPGYNPQYFSGAFQEMSNGGGVMSMPYQSWSTVRRERESFRNGGAQLTRGYSVSRVDRNLAEHIERKISGFPEEQRDYPVYSPYQYEYEGRGSDCQSLDQLSVSNLGDNLDFLQHLGPKFNNLGKICQQPVNHRNTQL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : *: * * : : * *:*****::*::*:*: **** : ::**: . .: : * * ** * *****:::: .* ::***.:***:.* * * **.:::.** :* :* **:.* *:**:** *. . : :* *. * : : * *:::* **:. ::** * : .:* : :: :***:.::.* :.:::.* * * *.::**:*: *.: :.*.* * * . *: .: * . .: :* : : * *:* *.* *: *.* .*****:: * ***:**:*:*.:** ::*. .* :.***:*::. * *: .. :: *:*:* * ****.*: * .::.. *. * : * .:***:**:** :**:** ::* : * : :*****.*.:. *.::::*:*:* ** *.* *::::*.*:***.* * ... * : : : : . * * *::.****.*.: :. * * . * . .* * *:* *:* *** * *:*.* .. .:.* :* * * * * *: : *.:: *: ** : * : .*.*:***: ** *. . : . ::. .. : . : * : :: .:.* .:*: : . . * *: * **. .. :*..*: : . .:* *.* . : . ", "identical_positions": 223, "similar_positions": 242, "identity": "25.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-197", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5HZJ5-1", "uniprot_id": "EREP3_MOUSE", "id": "Q5HZJ5-1", "name": "Protein ENTREP3", "aln": "MMPSPSDSSRSLTSRPSTRGLTHLR---LHRPWLQALLTLGLAQVLLGILVITFSMVASSVTTTESIKRSCPSWAGFSLAFSGLVGIVSWKRPFTLVISFFSLLSVLCVMLSMAGSVLSCKNAQLARDFRECSMEGKVCVCCPPIPLHRPCPEWGQELKVALNSTCDEARGALKNLLFSVCGLTICAAIICTLSAIVCCVQIFSLDLVHMQLAPERSVSGPLGPLACTSSPPAPLLHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSITYNGSMDSPVPLYPTDCPPSYEAVMGLRRDSQATLFDPQLHDGSCVCER-VASIVDVSMDSGSLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVDYVLFRSIQRSRAGYCLSLDCGLRGPFEDSPLPRRPPRAARSYSCSAP--------EAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRR--VP--RGGSRSAAPPPARAPARRFSDSSGSLTPPGHRP----------PHRTPPPPLLLPRSHSDPGITTSSDIADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARCPSPK-LLRARSAEKRRPVPTFQKVPLPSGPTP---AHSLGDLKGSWPGRGLVTRFLQLSRR----SPDPTGTGAHGYK------------QVRRSPWGR--------------------------------PGRES-LHLRSCGDLSSGSSLRRLLSARRLEHGIRPHSLSLNGGSRETGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P81408-1", "uniprot_id": "EREP3_HUMAN", "id": "P81408-1", "name": "Protein ENTREP3", "aln": "MMPSPSDSSRSLTSRPSTRGLTHLR---LHRPWLQALLTLGLVQVLLGILVVTFSMVASSVTTTESIKRSCPSWAGFSLAFSGVVGIVSWKRPFTLVISFFSLLSVLCVMLSMAGSVLSCKNAQLARDFQQCSLEGKVCVCCPSVPLLRPCPESGQELKVAPNSTCDEARGALKNLLFSVCGLTICAAIICTLSAIVCCIQIFSLDLVHT-LAPERSVSGPLGPLGCTSPPPAPLLHTMLDLEEFVPPVPPPPYYPPEYTCSSETDAQSITYNGSMDSPVPLYPTDCPPSYEAVMGLRGDSQATLFDPQLHDGSCICER-VASIVDVSMDSGSLVLSAIGDLPGGSSPSEDSCLLELQGSVRSVDYVLFRSIQRSRAGYCLSLDCGLRGPFEESPLPRRPPRAARSYSCSAP--------EAPPPLGAPTAARSCHRLEGWPPWVGPCFPELRRR--VP--RGGGRPAAAPPTRAPTRRFSDSSGSLTPPGHRP----------PHPASPPPLLLPRSHSDPGITTSSDTADFRDLYTKVLEEEAASVSSADTGLCSEACLFRLARCPSPK-LLRARSAEKRRPVPTFQKVPLPSGPAP---AHSLGDLKGSWPGRGLVTRFLQISRK----APDPSGTGAHGHK------------QVPRSLWGR--------------------------------PGRES-LHLRSCGDLSSSSSLRRLLSGRRLERGTRPHSLSLNGGSRETGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IZW2-1", "uniprot_id": "A0A0R4IZW2_DANRE", "id": "A0A0R4IZW2-1", "name": "", "aln": "-MPSPSDSS-SVASMSGSRALSGSRRGMSGRTSARVLLYLGLCHLALGAMVLAFSFTSLAFTSSPRVRQSCPFWAGFFVVASGVVGVISWRRPFTLVVSLFMLLSAVCVILSLAGSMLSCQNAQMVKSYVDCKVENRLCLCCEPKSCS---LKEDDTLVLYQHKDCHAVRHQLKDLLFSACGLSILSTIICTLSTVTCSIHIFSLDLLHL-LAPHRSRS--VNP-ECTT-PQDAFLSNMMDFEEFVPPIPPPPYYPPEYTCSSETDAQSVTYNGSMESPVPLYPTDCPPPYEAVMGQRAPSQATVYDTQAGELSGERGTSTAFSGEVSMDSGSLLMSEIVDIPDDSSPSEDSCLMEVGVGVRARSRGASEGGEGGECANFRSSPQHPEG-MVAAATGRRCFRGERSNSCSSPSTYNTSTYRSPVLRRQALLASSCSQLEFLTVSQHSSIPEIRVRPCTPSRRGSSSVFSNPPSTAPSGPAQDRP-DLTVQANPPRPVFREQIVRDRKNSDGFLPLLRSHSEPGLSSSTDTGDFSLSGGSKGVSEGGSQTSSETGVLSGAGLLPRSSLALPASLPRKGSIKALSSRLPIKQVPATSLRLPKDCARSLGDLK---VTRVLVQRFLQRSKRNLAPASDHTANCTQGPKRRTGGESSLPLEQVLRNSMGANRGQQQHVHHHCRGHHHSHSDSRHNARRHDDDPARARGIHLRSCGDLSSTS----VVSLRRLHP---PHGSSGAFYS-ESAL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******** *::* ..:*.*: * *. :.** *** :: ** :*::**:.: :.*:: :::*** **** :. **:**::**:******:*:* ***.:**:**:***:***:***:.:.: :*.:*.::*:** . . : .: * : :. *. .* **:****.***:* ::******::.*.::******:* ***.** * :.* **: * .:* .*:*:******:********************:******:************.****** * ****::*.* : * .* :********::* * *:*..*********:*: .**: . .. : .... * .* : :. ** *. ** ***:* .:* . * ** :** . ..:**:* * .* **.. : **: **: .* . .** .: * : . * * ****:**:::*:* .** . .*..* :*::**: * * *: : . * * * * : . .:::** .* * *:****** * ** **** *:: :.* :.. ::* * ** *. * *.* :********** * ::* ***. **. * * *:.*", "identical_positions": 295, "similar_positions": 180, "identity": "39.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-200", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5EE01-1", "uniprot_id": "CENPW_HUMAN", "id": "Q5EE01-1", "name": "Centromere protein W", "aln": "MALSTIVSQRKQIKRKAPRGFLKRVFKRKKPQLRLEKSGDLLVHLNCLLFVHRLAEESRTNACASKCRVINKEHVLAAAKVILKKSRG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3URR0-1", "uniprot_id": "CENPW_MOUSE", "id": "Q3URR0-1", "name": "Centromere protein W", "aln": "MAPSTTVTRR--VKRKAPRAFLKRTLKQKKPHLGLGRCCDLLIHLNCLLFIQRLAEESRTNACESKSRVIKKDHVLAAGKVILKKSRG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IXK5-1", "uniprot_id": "A0A0R4IXK5_DANRE", "id": "A0A0R4IXK5-1", "name": "", "aln": "------------MSKKAPRAALKHHMK-KNANIRIGKNADLMAQLNLLMVLHRLAEECRVKAFEEKSATIKTHHVRAVAKKLLKSTRG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.:****. **: :* *:.:: : : **: :** *:.::*****.*.:* .*. .*:..** *..* :**.:**", "identical_positions": 30, "similar_positions": 32, "identity": "34.09%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-201", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAC3-1", "uniprot_id": "F1MAC3_RAT", "id": "F1MAC3-1", "name": "", "aln": "MLGGLGVLRTLPL---LLLFLSEACLGPGCQALMLERDPPSLTVNLGEEAVLTCKNDG-KNPNITWWF--------SLQSNSTWPPMPLGPGLGPMG-----KLIFPEVNKSHRGLYWCQVIESKE-VKRSCGTYLRVRKQVPRPFLDMGEGTKNRIITAEGIILLFCAVVPGTLLLFRKRWQNEKFGVDMPDDYEDENLYEGLNLDDC-SMYEDISRGLQGTYQDVGSLHIGDVQLEKP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P11911-1", "uniprot_id": "CD79A_MOUSE", "id": "P11911-1", "name": "B-cell antigen receptor complex-associated protein alpha chain", "aln": "MPGGLEALRALP----LLLFLSYACLGPGCQALRVEGGPPSLTVNLGEEARLTCENNG-RNPNITWWF--------SLQSNITWPPVPLGPGQGTTG-----QLFFPEVNKNHRGLYWCQVIENNI-LKRSCGTYLRVRNPVPRPFLDMGEGTKNRIITAEGIILLFCAVVPGTLLLFRKRWQNEKFGVDMPDDYEDENLYEGLNLDDC-SMYEDISRGLQGTYQDVGNLHIGDAQLEKP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P11912-1", "uniprot_id": "CD79A_HUMAN", "id": "P11912-1", "name": "B-cell antigen receptor complex-associated protein alpha chain", "aln": "MPGGPGVLQALPATIFLLFLLSAVYLGPGCQALWMHKVPASLMVSLGEDAHFQCPHNSSNNANVTWWR--------VLHGNYTWPPEFLGPGEDPNG-----TLIIQNVNKSHGGIYVCRVQEGNESYQQSCGTYLRVRQPPPRPFLDMGEGTKNRIITAEGIILLFCAVVPGTLLLFRKRWQNEKLGLDAGDEYEDENLYEGLNLDDC-SMYEDISRGLQGTYQDVGSLNIGDVQLEKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P8N4-1", "uniprot_id": "A0A8M1P8N4_DANRE", "id": "A0A8M1P8N4-1", "name": "", "aln": "----------MGFRLVLFLSFFAAVLSGKLEDLQLEPDEPLLRVQVSQEATVRCCYRCKESPEVSWIKNTPAINGTTMPDLVNFTKNVMNKPEGEKDGVICHSLVFKSVSVNDMGLYQCKLKHGLL-TFFSHGTFLQIYLPLEK-TLNLSEGVKNSIITVEGVLLLMCVLIPGTMLLCKSKKVN---KLDRKTEREEENIYEGLNLDDCNSAYHQIQRSIQQGPYEDVACCEEDIQLEKP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:: : . *. : * :. . * *.:.::* . * ...:::* : . .:. :. . . *.: .*. .. *:* *:: .. * **:*:: : *::.**.** ***.**::**:*.::***:** :.: * :* : *:**:********* * *.:*.*.:* : * *****", "identical_positions": 60, "similar_positions": 71, "identity": "25.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-206", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A907-1", "uniprot_id": "D4A907_RAT", "id": "D4A907-1", "name": "", "aln": "MLGEAFLTEFFYKEQK-HAKLYKPLRCKKTPNDKKENWENKLLDTQDNSLPLLKTGSQEKVIEGSLTEQDNDTSQMKCVDDLTVAKCKSTALPGNVSVALPIPKRG-HDETQLDLYRSWSCTSICQNYPDLQIGGDHIRNMYDSGCFVEHIHDDVCNGPLLLSVDIPLGHSAKIEPLEKTSNSKVVNGDEIREKSMLLHKQPLSNSMLNNYMERKVDELYKQFLEENLTRCLSITNLMASSILMNNVNQISLQISQEQNIEPSKAREALLHSLALYNLCNVSHGNSTELSTPNLQISNQAIREFV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2BCG4-1", "uniprot_id": "A0A8M2BCG4_DANRE", "id": "A0A8M2BCG4-1", "name": "", "aln": "MLGEASLYVLNCTEEATNHDGYN--RARSSPS----------VTCPDATNATARPALTPRTVRAGRPESLKN-----------AGQCRASAP----SKAMPIHSCDREDRLGMSVYCSWCCPSIYKDYPDLRLGGDRLEPWSPQ------NPDPADDGPLLQSQDLSS-LEPSLKPSQQAVTQQDEEYLVMESAHSPDWQKRLTNSMLNGYLEVQMLEVFCQHMQNMACCGSSLLGPDVMPTLVPTVADKEQTTSRAEELDSS-------SSNVVRYLSTCSAPATSHFSSPVLRISEAE-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** * : .*: : . *: *.:.:*. : * : . :.. :.:... .*. :: ..:*:::* * *:** . . .*. :.:* **.*.** ::****::***::. . * . :**** * *:. ...::* ::: ..: : :.. :: *:*****.*:* :: *:: *.::: *: . . . *: .* : . *: ::::.* * .: *.. * ::.:*:* *:**: ", "identical_positions": 63, "similar_positions": 108, "identity": "20.66%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-222", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LV60-1", "uniprot_id": "F1LV60_RAT", "id": "F1LV60-1", "name": "", "aln": "--------MFNQQLQQ-----QQQLQQLQQQQLQQQ---QQQILQLQQLLQQSPPQASLSMPVSRGLPQQSSPQQLLNLQGLNSTSL-----------LNGSMLQRALLLQQLQGLDQFAMPPATYDSASLTMPTAALGNLRAYNVTAPNLAAPSLTPPQMVTPNLQQFFPQATRQSLLGPPPVGIPINPSQHNHSGRNSQKQPRTPSSTTPNHKDSSSQTVPLDDREDPTEGSEEATELQMDTAEDQDSLVFPDGLASEPQVHEPEPEPFEALEPPAKRLRSSEESTEKGPTGQPQARVQPQTQMTAPKQTQTPDQLPEPPEALVVPRIQPQVLQIQT-----------------LSKLQKQAQTQTSPEHLAPQQNQVQPQVR--SQPQWQLQP-----------------WETDPPKQAQAQTQP----QPLWQAQSHKQAQTQTQTHPQVSTQAQPQEQ------------TSEKTQDQPQTWPQGSAPPPEQASVPACATEPQLLSNAAEVGRDPEETLPEPVSAQSSEDRSQEPSAGGLDVGECEKRAGEVLGMWGAGSSLKVTILQSSNSRAFNTTPLTSGPRPGDSASATPALASTPSKQSLQFFCYICKASCSSQQEFQDHMSEAQHQQRLGEMQHSSQTCLLSLLPMPRDILERET-----EDPPPKRWCNTCQVYYMGDLIQHRRTQEHKVAKQSLRPFCTICNRYFKTPRKFVEHVKSQGHKDKAQELKTLEKETGS----PDEDHFITVDAVGCF--------------------------------------------------------------------------------------------ESGQEEDEDDDEEEEEEIEAEEEFCKQLQSRETSSEQWKDSETYSPNTAYGVDFLVPVMGYV----CRICHKFYDSNSEFRLSHCKSLAHFENLQKYKAK----NPSPPTRPVSRKCAINARN------------ALTALFTSSSGSSRQ-----------PSPQDTVKIPSKVTCFPEAVILAFRARIHRHA-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ULV3-1", "uniprot_id": "CIZ1_HUMAN", "id": "Q9ULV3-1", "name": "Cip1-interacting zinc finger protein", "aln": "--------MFSQQQQQQLQQQQQQLQQLQQQQLQQQQLQQQQLLQLQQLLQQSPPQAPLPMAVSRGLPPQQPQQPLLNLQGTNSASL-----------LNGSMLQRALLLQQLQGLDQFAMPPATYDTAGLTMPTATLGNLRGYGMASPGLAAPSLTPPQLATPNLQQFFPQATRQSLLGPPPVGVPMNPSQFNLSGRNPQKQARTSSSTTPNRKDSSSQTMPVEDKSDPPEGSEEAAEPRMDTPEDQDLPPCPEDIAKEKRTPAPEPEPCEASELPAKRLRSSEEPTEKEPPGQLQVKAQPQARMTVPKQTQTPDLLPEALEAQVLPRFQPRVLQVQAQVQSQTQPRIPSTDTQVQPKLQKQAQTQTSPEHLVLQQKQVQPQLQQEAEPQKQVQPQVQPQAHSQGPRQVQLQQEAEPLKQVQPQVQPQAHSQPPRQVQLQLQKQVQTQTYPQVHTQAQPSVQPQEHPPAQVSVQPPEQTHEQPHTQPQVSLLAPEQTPVVVHVCGLEMPPDAVEAGGGMEKTLPEPVGTQVSMEEIQNESACGLDVGECENRAREMPGVWGAGGSLKVTILQSSDSRAFSTVPLTPVPRPSDSVSSTPAATSTPSKQALQFFCYICKASCSSQQEFQDHMSEPQHQQRLGEIQHMSQACLLSLLPVPRDVLETED-----EEPPPRRWCNTCQLYYMGDLIQHRRTQDHKIAKQSLRPFCTVCNRYFKTPRKFVEHVKSQGHKDKAKELKSLEKEIAG----QDEDHFITVDAVGCF--------------------------------------------------------------------------------------------EGDEEEEEDD--EDEEEIEVEEELCKQVRSRDISREEWKGSETYSPNTAYGVDFLVPVMGYI----CRICHKFYHSNSGAQLSHCKSLGHFENLQKYKAAK---NPSPTTRPVSRRCAINARN------------ALTALFTSSGRPPSQ-----------PNTQD--KTPSKVTARPSQPPLPRRSTRLKT------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AS23-1", "uniprot_id": "A0A8M3AS23_DANRE", "id": "A0A8M3AS23-1", "name": "", "aln": "---------------------MVRMFNPHQHQQQQQHQFHQHLRQLQQLFQQQTPPPPPPPPP----PPQPPPAHHITHH-HQAARY-----------PHAAPPHTNTAHTRPMAVPAPAPPPARMVNLCSATQTIIAPNPMLQGALLMQQMQGSMRGFAMGGQQFPPFFAAGSRASLLGPVPMGVAIK----------------TPHMGFPRHFTPHARYFPNDYQTPQPDRKREIEQKSANISSGHS--------AASSSNGQPEAARSSNGQSAAKSSSSNDQSAANSSSNGQSVASSSNGQSEAKSSSSSSSSRADEAVAVADPGSQ--------------------------GSSEQPDEPAAKKHKTQESEEPLEKDSAENTECKSPADAG---------------------------------------------------------------------------------------DSLPEESVVNEPPATEAEEQCQADKQTDAADVDQPISGAPAD------------------------------------AGSSDSVSAVKQPE----------AAPVQHQLTDTAAAAESSSS-----FFCYICNITCHNQQNFQSHMNGLTHQQKMMEIQHMSNACLVTLLPRVQESLQGAARKDGEKRPGLQRWCSTCQTHFTSNVMEHRRTKEHKRFSRSSSSSCTVCKLNFRTAREFVEHMQSAEHKQRVQQLW---KESGS----GSVEELNTVMLLGED--------------------------------------------------------------------------------------------DGEFCSDDER----EDEENGKEGLSAQM---EVTMEDLDEDEEFDSDTVYGSSFVVPVSGFL----CRLCDQFYHYESSARHAHCKTLKHFQNLKRYKALKKHEDSGSTSAEAAEEVAVAAAEGLLIAEESSVDPSASPITNTSSTPPQQEEKLEPEETLKPEPEPESELEEKLEPEPELEERSSERGRGRTSAKRRGRGGRRR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P41073-1", "uniprot_id": "PEP_DROME", "id": "P41073-1", "name": "Zinc finger protein on ecdysone puffs", "aln": "-------------------MVSVKVNGNPQNRLVNNAKVNGNMAFRGNQNRNRNFGGGNNNYGGPMGANRMGGMNMSPWESQNPGGG-----------QFGNNMRQGGGQMNAQAINLANNLLNNLFRNQNPPSLLDLPRGGGGMGNRNQRGGPMVSRGGGAGNRLNNRRGQGGGFQNRGATGSGPKPPP---------------KQGGGGIRKQNAFDRAKKLLAKNANQNKKKEPTPGEKKIESPTK---------ESPYASVPNDMFYCHLCKKHMWDANSFENHIKGRTHLMMREGIEESYRLKANMIRQEAKIAEQLKSIEFDRLKRMG-----------------------KSKQRQLDYCTMCDLNFHGHISTHRKSEGHLQLKKFLHPK-------------------------------------------------------------------------------------CIECNKEFATRIDYDTHLLSAEHLKKAAENNTKVGERKRQTLPISTE---------------------------------EEETRDLRLPQKRKKK--------PVKKEGEAADGEAKKEGAGD-------GEGAEGDEAEGEEAKEGEEAADETKEGDELNESQEEEEVALPVDPEDCILDFN-----DGDEIPSEVDTRLPKYN-----WQRAVGPGLISKLECYECSVCSKFFDTEVTAEIHSRTATHHRNFLKFINEKSSDTK----IAQKRAAAALEENER--------------------------------------------------------------------------------------------KKRKVEEAEAPAAEGAAEETTEGAEGELYDPSEATGDDEDVEMVDDNAEG------EGEGEG----DEEAEAEVEEDGAGQDNGEEEMEAQEEEGQEGEQEPEPEPAPVQTPAPAEPAPPAKTPAKTPTKAAAPAAVASPAAAATSADAS-----------PSPAKKATPARAAAGAKATPQRQRARGRYNRY-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VT61-1", "uniprot_id": "Q9VT61_DROME", "id": "Q9VT61-1", "name": "", "aln": "MRGRGGFIPRGGGTTRGGYYNNRNSSNYVNTRTQGNYRPNNGRYENNYHNNNNRYNNHNNSGGGAGGNSHYDNRSRDKFTHHNSSSGRYESSSSSHKRSYDSSRDRSDDRKRPRQDDYRRTSSSNDRSDRPSSSSQNIGSSSSNYHQRSSTGGGGNNGGSSSSYRPRDDSTSGSRHQRDGSMGPPKRMMRSVAGTNYISRPRGTMSMRGGMMRTGMRVGGMRVVRTRVNESNDLRTMRRQLLYAQQKDRARLLKIQQLKSSLRRQRQGGNSSDDSSGKEDKDGEDAEKSKKKKGKDKDADGGDESDDDDDDEEDDDEKDEKSKKTSPGKKRNKS-----------------------ANNEDKSEAEGNDDDDDDDDEHGDGDDDDDKDLNESDPKS-----------------------------------------------------------------------------------AKADDASDDEDVKVKGDGEDGDGDKSDEKAKSSVEKSGKKKDKDDAKDSK--------------------------------SKKSSSTKKERTSRKDKDKESSGDDRSKERRSSRHRDEDHNNRKRSFIKLICVHCRIKCVTFKEYNYHLNSRSHKNSMRQVALNQRADLQRMRARQRTTQREIE--ENSKEEHESRYCRLCRLAYRQPKNLHQASEHHKTIKKFLMPYCGSCHLAFKNAMLYENHRCSLDHIRNKARNDESGSDDSVDEREIDLNKFHTVDSVGEIDVDMIDADVDAMVTEAEAALKSEDEETRKRALIGPDYIKVIEAFYCELCNHYSAKADDVSLEDYTKKHCMQHSHVKAFLRNKEETEKKNKTEEGDEDDHDDDKKAGDDDADGDEDIDGKLNEDDDEYDDDGDAEVEEGDATNDKKMWEEVDKDLGDLLAEVETRGHKEDEEDEEDESVLNIDIESEKNKAKDGKEEANGDTDEGAAKENAPVAKSPEKKHAASAPTTPTAKTTAAASQPAKMATPKPTAKATKPGPASTKRNVLVSVKRTSAAAIKAATKSASNAAAADSK-----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : : .: : :. . . . . . *. . . : : . . . : .. : : . : : . : : . . . . : : . : . . .. . : . : . . .. :: : . . : :: .. : . . : : : .: * * * . * : * . . .. .. :. . . .. : : * :: . : * . :: . . : . :. . . .. . * * . : :: . * . ", "identical_positions": 11, "similar_positions": 112, "identity": "1.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-224", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "H0UI37-1", "uniprot_id": "TSTD3_HUMAN", "id": "H0UI37-1", "name": "Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3", "aln": "--------------------------MKIEKCGWS----------EGLTSIKGNCHNFYTAISKDVTYKELKNLLNSKNIMLIDVREIWEILEYQKIPESINVPLDEVGEALQMNPRDFKEKYNEVKPSKSDS------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D0B5-1", "uniprot_id": "TSTD3_MOUSE", "id": "Q9D0B5-1", "name": "Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3", "aln": "----------------------MLARLVLGTSGRAALGSVE-PALGGLKSIWR-CSQAFCSTPKGVTYRELKSLLNSKDIMLIDVRNTLEILEQGKIPGSINIPLDEVGEALQMNPVDFKEKYCQVKPSKSDRLVFSCLAGVRSKKAMDTAISLGFNSAQHYAGGWKEWVTYEISEEKQES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F1E2-1", "uniprot_id": "E7F1E2_DANRE", "id": "E7F1E2-1", "name": "Sulfurtransferase", "aln": "MALNVCSRLTRNVVRVLANRSAIPVTRPLTRSSWTHLRYLHNISIIRYDSVSLRNFSSSSQPSVDVSYEQLKKLLVSGSSVVIDVREPWELREYGNIQGSINVPLGQVNGALQLTPDEFKEKYGGDMPSKSQNIVFSCLAGVRSKHALEAAVSLGYTKVQHFPGGWQEWAERELIQTKK--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. : *: . . .*:*.:**.** * . ::****: *: * :* ***:**.:*. ***:.* :***** ****: ", "identical_positions": 34, "similar_positions": 26, "identity": "18.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-225", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIA7-1", "uniprot_id": "SPHK2_MOUSE", "id": "Q9JIA7-1", "name": "Sphingosine kinase 2", "aln": "----------------------------------------------------------------------------------------------------------MAPPPLLPVAASTPILHG--EFGSYPANGPRFALT------LTTQALHIQRLR-----PKPEARPRDGLVSLDEVSGCGTLQS---------------RSPEDTAAYFCIYTYPRGRRGGRRRATRTFRADGATTYEENRAEAQRWATALTCLLRGVPLSGDQEITPELLPRKPR---LLILVNPFGGRGLAWQRCMDHVVPMISEAGLSFNLIQTERQNHARELVQGLS--LSEWEGIVTVSGDGLLYEVLNGLLDRPDWEDAVR-MPIGVLPCGSGNALAGAVNHHGGFEQVVGVDLLLNCSLLLCRGGSHPLDLLSVTLASGS---------------RCFSFLSVAWGFLSDVDIHSERFRALGSARFTLGAVLGLASLHTYRGRLSYLPATTEPALPIPGHSLPRAKSELVLAPAPAPAATHSPLHRSVSDLPLPLPQPALVSPG--------------------------------------------SPEPLPDLS------------------------LNGGGPELTG----------------DWGG--------------AGDAP------------------------------------------------------------------------------------------------------LSPDPLLPSSPNALKTAQLSPIAEGPPEMPASSGF-LPPTHSAPEASTWG---------------PVDHLLPPLGSPLPQ--DWVTIEGEFVLMLGILPS----HLCADLMAAPHARFDDGVVHLCWVRSGISRAALLRILLAMEHGNHFSLG-CPHLGYAAARAFRLEPLTPRGLLTVDGELVEYGPIQAQVHPGLATLLTGPAGQKPQA----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRA0-1", "uniprot_id": "SPHK2_HUMAN", "id": "Q9NRA0-1", "name": "Sphingosine kinase 2", "aln": "----------------------------------------------------------------------MNGHLEAEEQQDQRPDQELTGSWGHGPRSTLVRAKAMAPPPP-PLAASTPLLHG--EFGSYPARGPRFALT------LTSQALHIQRLR-----PKPEARPRGGLVPLAEVSGCCTLRS---------------RSPSDSAAYFCIYTYPRGRRGARRRATRTFRADGAATYEENRAEAQRWATALTCLLRGLPLPGDGEITPDLLPRPPR---LLLLVNPFGGRGLAWQWCKNHVLPMISEAGLSFNLIQTERQNHARELVQGLS--LSEWDGIVTVSGDGLLHEVLNGLLDRPDWEEAVK-MPVGILPCGSGNALAGAVNQHGGFEPALGLDLLLNCSLLLCRGGGHPLDLLSVTLASGS---------------RCFSFLSVAWGFVSDVDIQSERFRALGSARFTLGTVLGLATLHTYRGRLSYLPATVEPASPTPAHSLPRAKSELTLTPDPAPPMAHSPLHRSVSDLPLPLPQPALASPG--------------------------------------------SPEPLPILS------------------------LNGGGPELAG----------------DWGG--------------AGDAP------------------------------------------------------------------------------------------------------LSPDPLLSSPPGSPKAALHSPVSEGAPVIPPSSGLPLPTPDARVGASTCG---------------PPDHLLPPLGTPLPP--DWVTLEGDFVLMLAISPS----HLGADLVAAPHARFDDGLVHLCWVRSGISRAALLRLFLAMERGSHFSLG-CPQLGYAAARAFRLEPLTPRGVLTVDGEQVEYGPLQAQMHPGIGTLLTGPPGCPGREP---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TA20-1", "uniprot_id": "A0AB32TA20_DANRE", "id": "A0AB32TA20-1", "name": "sphingosine kinase", "aln": "------------------------------------------------------------------------MRSPGPDSPSMTEEALLHGQFG----------GWSSGGGSGSNSNSCPNSPGGVSLPSSPAS-TNYALT------LTPTHIHVQRLS-----PRAGKQSR-LLLPMAELTGCSCPRS---------------PAP----PLLVLYWYPPGRR--RKGVSRHRQVR--AYLAESRAEAEKWNAAIQSLLRGMDVSSTTEFCKSMLPRPRR---LLLLVNPFSGRGQAMQWCQTHILPMIREANISYNLIQTERQNHARELIREIS--LPEWDGIVIVSGDGLLHEVINGLMERPDWEQAIK-TPVGILPCGSGNALAGSINHHAGYDMCLREPLLLNCCFLLCRGGVKPLDLVSVTTSPCASSSTSNQNGHPPAPRRLFSFLSVAWGFVSDVDIESERYRGLGSARFTLGTLVRLASLRSYKGRLSYLPPAVVNPSPDATPQPPRRPLSRSITEG-LEGFCRTPIHRTCSDMGLSEQRSLRKDDGERERERERERQERERERERRRDRARGVGVVRASSLAEDREREVEAEEKMEEMSGTSSESTERDECDNIAKNNGNEEENNSGESKIDGQELTNARNLSDTNEVNDCDGSYQTTPPELQHALRKNSAPSSQIINAFFSQPIGADTDQDLELAAYGKEDEDINGTYFQKEAYSLDKSRERALTISSSPFRQSPFKAFKPKTLDQNQNPSRPRPLSLLHQSHSNSLPPKFPSLSPTPPSSPSCASPHSSYLAPRPNTPSSSSPSPSIHSPTPSFNFDLAEPAGPLKNRPHMTSSINLPEDDLLPPLDQPLPTR-DWVTIEGDFVLVLAIYQS----HLGADLLAAPQARFDDGLIHLTFVRAGISRATLLRLFLAMERGAHLSLS-SPYVSHVSARAFRLQPLSPRGTLTVDGELVPYGPLQAQVHPSMARLIVGDSGIKITRF---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06147-1", "uniprot_id": "LCB5_YEAST", "id": "Q06147-1", "name": "Sphingoid long chain base kinase 5", "aln": "MTLKPSKRRKGRSRHSRKKQITSAILTEEGIMIKAKPSSPYTYANRMADKRSRSSIDNISRTSFQSNISRTSFQSNSDNNSIFETASLISCVTCLSDTDTIDRSETSTTDTSKDDLSANPKLHYPSVNGQLPANTVIPYGRILDARYIEKEPLHYYDAN-----SSPSSPLSSSMSNISEKCDLDELESSQKKE---RKGNSLSRGSNSSSSLLTSR--SPFTKLVEVIFARPRRHDVVPKRVSLYIDYKPHSSSHLKEEDDL----VEEILKRSYKNTRRNKSIFVIINPFGGKGKAKKLFMTKAKPLLLASRCSIEVVYTKYPGHAIEIAREMD--IDKYDTIACASGDGIPHEVINGLYQRPDHVKAFNNIAITEIPCGSGNAMSVSCHWTN---------NPSYSTLCLIKSIETRIDLMCCSQPSYAR------------EHPKLSFLSQTYGLIAETDINTEFIRWMGPARFELGVAFNIIQKKKYPCEIYVKYAAKSKN----------------------ELKNHYLEHK--NKGSLEFQHITMNKDN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDCDNYNYENEYETENEDEDEDADADDEDSHLISRDLADSSADQIKEE----------------DFKIKYPLDEGIPS--DWERLDPNISNNLGIFYTGKMPYVAADTKFFPAALPSDGTMDMVITDARTSLTRMAPILLGLDKGSHVLQ---PEVLHSKILAYKIIPKLGNGLFSVDGEKFPLEPLQVEIMPRLCKTLLRNGRYVDTDFDSM", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12246-1", "uniprot_id": "LCB4_YEAST", "id": "Q12246-1", "name": "Sphingoid long chain base kinase 4", "aln": "MVVQKKLR---------------AILTDEGVLIKSQ-------SHHMFNKHG-------------------QLRSG-------DSLSLLSCLSCLDDGTLSSDGGSFDEDDSLELLPLNTTIPF---NRILNAKYVNVGQKGFNNGKISSNPFQTENLS-----SSSENDDVENHSLSNDKAPVSESQSFPKKDKWDTKTNTVKVSPDDSQDNSPSLGIKDNQQLIELTFAVPKGHDVIPQKLTLLIDHVSRKSRANTGEENISSGTVEEILEKSYENSKRNRSILVIINPHGGKGTAKNLFLTKARPILVESGCKIEIAYTKYARHAIDIAKDLD--ISKYDTIACASGDGIPYEVINGLYRRPDRVDAFNKLAVTQLPCGSGNAMSISCHWTN---------NPSYAALCLVKSIETRIDLMCCSQPSYMN------------EWPRLSFLSQTYGVIAESDINTEFIRWMGPVRFNLGVAFNIIQGKKYPCEVFVKYAAKSKK----------------------ELKVHFLENKDKNKGCLTFEPNPSPNSS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PDLLSKNNINNSTKD-----------------------ELSPNFLNED----------------NFKLKYPMTEPVPR--DWEKMDSELTDNLTIFYTGKMPYIAKDTKFFPAALPADGTIDLVITDARIPVTRMTPILLSLDKGSHVLE---PEVIHSKILAYKIIPKVESGLFSVDGEKFPLEPLQVEIMPMLCKTLLRNGRYIDTEFESM", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VYY8-1", "uniprot_id": "Q9VYY8_DROME", "id": "Q9VYY8-1", "name": "sphingosine kinase", "aln": "-----------------------------------------------------------------------MTANTGTSGENLMGNGGKTHEPSTPTSDTEVASGTPTELSEIFFVDNSRRKQSIKIQVKLCPEGVYLRRETEEDDHINEQLIRIDDIIGSRYGRRLKKRARGGLNSCRNPNVPGQEADS-------------EPDSDNSAYLYIYAYLKKEKPLRRVQTLRILRFRSSNDYGVNLQTAEMWHHTIRKHKRGNGSSSPADCGKQ----------LLILLNPKSGSGKGRELFQKQVAPLLTEAEVQYDLQITTHPQYAKEFVRTRRDLLTRYSGIVVASGDGLFYEVLNGLMERMDWRRACRELPLGIIPCGSGNGLAKSVAHHCN--EPYEPKPILHATLTCMAGKSTPMDVVRVELATRDK------------HFVMYSFLSVGWGLIADIDIESERLRSIGAQRFTLWAIKRLIGLRSYKGRVSYLLGKGKKEPPVEAARELPAESTAAGIRSSLPLNAGEFHDLPEEEEGEAVLDGEQFADAISLDR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVYRQHADSWHSAMSRRTAYYSLGGPSMRSNRSRMSISQRIEAANAEFAERVP----------------TGTIPPLQMPLLSSDGWICEDGDFVMVHAAYTT----HLSSDVFFAPESRLDDGLIYLVIIRRGVSRHQLLNFMLNLNAGTHLPIGEDPFIKVVPCRAFRIEPSSSDGILVVDGERVEYGPIQAEVMPGLINVMTTSGQ---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :: : . . . . : :::::** .* * . : : *:: : . :: * :* :: : : .:. *. .****: :**:*** * * * . .: :******.:: : . : . :*:: .. **** :*.::: **.:* * :*. ** * . : :.* .: . .. *: : .* : :: : :: * * : ** : : . : ::* :: * *. * : *::: * * : **** . *:*.:: * : : ", "identical_positions": 61, "similar_positions": 103, "identity": "6.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-229", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M5Q6-1", "uniprot_id": "F1M5Q6_RAT", "id": "F1M5Q6-1", "name": "", "aln": "MAAVAGDSAMEVVPALAEEAAAEASGPSCLVQLPGEVLEYILCSGSLTALDIGRVSSTCRRLREVCQSSGQVWKEQFRVRWPSLMKHYSPTDYVNWLEEYKVRQKAGLEARKIVASFSKRFFSEHVPCNG------FSDIENLEGPEIFFEDELVCILNMEGRKALTWKYYAKKILYYLRQQKILNNLKAFLQQPDDYESYLEGAVYIDQYCNPLSDISLRDIQAQIHSIVELVCKTLRGINSRHPSLTFRAGESSMIMEIELQSQVLDAINYVLYDQLKFKGNRMDYYNALNLYMHQVLTRRTGIPISMSLLYLTIARQLGVPLEPVNFPSHFLLRWCQGAEGATLDIFDYIYIDAFGKGKQLTVKECEYLIGQHVTAALYGVVNVKKVLQRMVGNLLSLGKR-EGIDQSYQLLRDSLDLYLAMYPDQVQLLLLQARLYFHLGIWPEKSFCLVLKVLDILQHIQTLDPGQHGAVGYLVQHTLEHIERKKEEVGVEVKLRSEEKHRDVCYSIGLVMKHKRYGYNCVIYGWDPTCMMGHEWIRNMNVHSLPHGHHQPFYNVLVEDGSCRYAAQENLEYNVEPQEISHPDVGRYFSEFTGTHYIPNAELEIRYPEDLEFVYETVQNIYSAKEDTAE-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDH1-1", "uniprot_id": "FBX21_MOUSE", "id": "Q8VDH1-1", "name": "F-box only protein 21", "aln": "MASVAGDSAMEVVPALAEEAAAEATGPSCLVQLPGEVLEYILCSGSLTALDIGRVSSTCRRLREVCQSSGQVWKEQFRVRWPSLMKHYSPTDYVNWLEEYKVRQKAGLEARKIVASFSKRFFSEHVPCNG------FSDIENLEGPEIFFEDELVCILNMEGRKALTWKYYAKKILYYLRQQKILNNLKAFLQQPDDYESYLEGAVYIDQYCNPLSDISFRDIQAQIHSIVELVCKTLRGINSRHPSLTFRAGESSMIMEIELQSQVLDAINYVLYDQLKFKGNRMDYYNALNLYMHQVLTRRTGIPISMSLLYLTVARQLGVPLEPVNFPSHFLLRWCQGAEGATLDIFDYIYIDAFGKGKQLTVKECEYLIGQHVTAALYGVVNVKKVLQRMVGNLLSLGKR-EGIDQSYQLLRDSLDLYLAMYPDQVQLLLLQARLYFHLGIWPEKSFCLVLKVLDILQHIQTLDPGQHGAVGYLVQHTLEHIERKKEEVGVEVKLRSEEKHRDVCYSIGLVMKHKRYGYNCVIYGWDPTCMMGHEWIRNMNVHSLPHGHHQPFYNVLVEDGSCRYAAQENLEYNVEPQEISHPDVGRYFSEFTGTHYIPNAELEIRYPEDLEFVYETVQNIYSAKEDTAE-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94952-2", "uniprot_id": "FBX21_HUMAN", "id": "O94952-2", "name": "F-box only protein 21", "aln": "MAAAAVDSAMEVVPALAEEAAPEVAGLSCLVNLPGEVLEYILCCGSLTAADIGRVSSTCRRLRELCQSSGKVWKEQFRVRWPSLMKHYSPTDYVNWLEEYKVRQKAGLEARKIVASFSKRFFSEHVPCNG------FSDIENLEGPEIFFEDELVCILNMEGRKALTWKYYAKKILYYLRQQKILNNLKAFLQQPDDYESYLEGAVYIDQYCNPLSDISLKDIQAQIDSIVELVCKTLRGINSRHPSLAFKAGESSMIMEIELQSQVLDAMNYVLYDQLKFKGNRMDYYNALNLYMHQVLIRRTGIPISMSLLYLTIARQLGVPLEPVNFPSHFLLRWCQGAEGATLDIFDYIYIDAFGKGKQLTVKECEYLIGQHVTAALYGVVNVKKVLQRMVGNLLSLGKR-EGIDQSYQLLRDSLDLYLAMYPDQVQLLLLQARLYFHLGIWPEKSFCLVLKVLDILQHIQTLDPGQHGAVGYLVQHTLEHIERKKEEVGVEVKLRSDEKHRDVCYSIGLIMKHKRYGYNCVIYGWDPTCMMGHEWIRNMNVHSLPHGHHQPFYNVLVEDGSCRYAAQENLEYNVEPQEISHPDVGRYFSEFTGTHYIPNAELEIRYPEDLEFVYETVQNIYSAKKENIDE----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T7V0-1", "uniprot_id": "A0A8N7T7V0_DANRE", "id": "A0A8N7T7V0-1", "name": "", "aln": "MATPYTG-----DRVLGTNVVTSGRFSKQLIDLPAEILEHILCFPVLNPVDICNVSSTCKRLHDVCHGRGKVWAHQYKLRWPRLQRFYRQNESYDWLKEFKTRHTVGQQIRRTVESISKRFFTE-VPCIGQVLGDSFAEIESLGAPEHFCEDELLGILNSDKRKSLTLKYYAKKILYFFRQQNILRNLKVFLERPPEQQSALEGAVLVDQYCNPLTDVTFESISAQVEEITDKVKKCLRAQNAAHPSLRAGQGECFVLEDFEFQRQVICAVNTVLYEQLQYKGNERDYYNPLNSYIHQVLLRRTGIPISLSVLYMTLARKLGVPLEPVNFPNHFLLRWCQ-NQRRCGDIYDYIYIDAFGNGKQLAAKECEILIKHQATADYYSAISTSELLLRMVGNLLNIGMRGEGNEKSYQLLRDSLDLYLSINPDNVQYLLLQARLYFHLGIWPEK-------VLDILQHIQALDPSQHGAVGYLVQHTLEHIQHKRHPVEPEVKRRSAPEHRDVQFSTGLIMKHKRSGYNCVIYGWDPKCTMSQEWINTMRVHQLSKGADQPFYNVLVQDGTCRYAAQENLEPHSAPLEIAHPEIGRYFNEFSETHYISNEELQARYPEDMCKTNRTVEELYHSLTPNSGQSPEPTANFQDHDLLDP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: . .*. :.... . *::**.*:**:*** *.. ** .*****:**:::*:. *:** .*:::*** * :.* .: :**:*:*.*:..* : *: * *:*****:* *** * *::**.* .** * ****: *** : **:** *********::***:**.***.**::* : :* ***** :*******:*:::..*.**:..*.: * * **. *: **** **. :: ::*:* **: *:* ***:**::***. ****.** *:**** ********:*:**:*:**:***********.******** : **:*********:****:.**** ** ::.** *..:...::* *******.:* * ** ::*************:: **:** ***************** *********:***.****************::*:. * *** ** :**** :* **:***** ***********.* *.:***..*.**.*.:* .********:**:********** : * **:**::****.**: ****.* **: *****: . .**:::* : . ", "identical_positions": 360, "similar_positions": 155, "identity": "55.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-230", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14135-1", "uniprot_id": "VGLL4_HUMAN", "id": "Q14135-1", "name": "Transcription cofactor vestigial-like protein 4", "aln": "-----METP-LDVLSRAASLVHADDEKREAALRGEPRIQTLPVASALSSHRTGPPPISPSKRKFSMEPGDEDLDCDNDHVSKMSRIFNPHLNKTANGDCRRDPRERSRSPIERAVAPTMSLHGSHLYTSLPSLGLEQPLALTKNSLDASRPAGLSPTLTPGERQQNRPSVITCASAGARNCNLSHCPIAHSGCAAPGPASYRRPPSAATTCDPVVEEHFRRSLGKNYKEPEPAPNSVSITGSVDDHFAKALGDTWLQIKAAKDGASSSPESASRRGQPASPSAHMVSHSHSPSVVS------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80V24-1", "uniprot_id": "VGLL4_MOUSE", "id": "Q80V24-1", "name": "Transcription cofactor vestigial-like protein 4", "aln": "MLFMKMDLLNYQYLDKMNNNIGVLCYEGEASLRGEPRMQTLPVASALSSHRTGPPPISPSKRKFSMEPGDKDLDCENDHVSKMSRIFSPHLNKTVNGDCRRDPRERSRSPIERAAAPAVSLHGGHLYASLPSL-MEQPLALTKNSSDTGRSA--------VERQQNRPSVITCASAGARNCNLSHCPIAHSGCSAPGSASYRRPPSATATCDPVVEEHFRRSLGKNYKEPEPAPNSVSITGSVDDHFAKALGDTWLQIKAAKDSASSSPESASRRGQPASPTAHMVSHSHSPSVVS------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AA52Z6R1-1", "uniprot_id": "A0AA52Z6R1_DANRE", "id": "A0AA52Z6R1-1", "name": "", "aln": "-----MDILINEIINKMNNNISG----LQCNLYGEDGSE----ASRVPVLDSECPPVSPTKRKH-----HENKDSDKGQMNKMRCLFASHLTNPNESTANQESWNVS----SHGHSGLSGLHSHHVFAPFPIFAFDRPFEMNQQSLHPTSSMLPTPG-TTTKQQQNRPSVITCAPASNRPCSLSSCHMSPDSCTSGSAN----KTNANNVCDPVIEEHFHRSLGDIYKEALPISNSVSTTGSVDDHFTKALGDAWLQIKAKGNSGTAPNHVVSKTAASTSLDSEASIYHHTVVSISDIFWENWTLCTSDQKRKGSSRLLPVQKTQKPGPIMV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: : :.: . : :. * ** : ** :. : **:**:***. .:: *.::.::.** :* .**.:. :. ..::. : * .:. : .**. *:::.:* : :::*: :.::* .. . ::***********.*. * *.** * :: ..*:: .. ..* .****:****:****. ***. * .**** ********:*****:****** :..::. . .*: . .:* :. : *: :* ", "identical_positions": 88, "similar_positions": 102, "identity": "26.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-236", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6EMB2-1", "uniprot_id": "TTLL5_HUMAN", "id": "Q6EMB2-1", "name": "Tubulin polyglutamylase TTLL5", "aln": "MPIVMARDLEETASSSEDEEVISQEDHPCIMWTGGCRRIPVLVFHADAILTKDNNIRVIGERYHLSYKIVRTDSRLVRSILTAHGFHEVHPSSTDYNLMWTGSHLKPFLLRTLSEAQKVNHFPRSYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYSKDRGPWIVKPVASSRGRGVYLINNPNQISLEENILVSRYINNPLLIDDFKFDVRLYVLVTSYDPLVIYLYEEGLARFATVRYDQGAKNIRNQFMHLTNYSVNKKSGDYVSCDDPEVEDYGNKWSMSAMLRYLKQEGRDTTALMAHVEDLIIKTIISAELAIATACKTFVPHRSSCFELYGFDVLIDSTLKPWLLEVNLSPSLACDAPLDLKIKASMISDMFTVVGFVCQDPAQRASTRPIYPTFESSRRNPFQKPQRCRPLSASDAEMKNLVGSAREKGPGKLGGSVLGLSMEEIKVLRRVKEENDRRGGFIRIFPTSETWEIYGSYLEHKTSMNYMLATRLFQDR-------------MTADGAPELKIESLNSKAKLHAALYERKLLSLEVRKRRRRSSRLRAMRPKYPVITQPAEMNVKTETESEEEEEVALDNEDEEQEASQEESAGFLRENQAKYTPSLTALVENTPKENSMKVREWNNKGGHCCKLETQELEPKFNLMQILQDNGNLSKMQARIAFSAYLQHVQIRLMKDSGGQTFSASWAAKEDEQMELVVRFLKRASNNLQHSLRMVLPSRRLALLERRRILAHQLGDFIIVYNKETEQMAEKKSKKKVEEEEEDGVNMENFQEFIRQASEAELEEVLTFYTQKNKSASVFLGTHSKISKNNNNYSDSGAKGDHPETIMEEVKIKPPKQQQTTEIHSDKLSRFTTSAEKEAKLVYSNSS---SGPTATLQKIPNTHLSS-VTTSDLSPGPCHHSSLSQIPSAIPSMPHQPTILLNTVSASASPCLHPGAQNIPSPTGLPRCRSGSHTIGPFSSFQSAAH----IYSQKLSRPSSA-KAG-SCYLNKHHSGIAKTQKEGEDASLYSKRYNQSMVTAELQRLAEKQAARQYSPSSHINLLTQQVTNLNLATGIINRSSASAPPTLRPIISPSGPTWSTQSDPQAPENHSSSPGSRSLQTGGFAWEGEVENNVYSQATGVVPQHKYHPTAGSYQLQFALQQLEQQKLQSRQLLDQSRARHQAIFGSQT-LPNSNLWTMNNGAGCRISSATASGQKPTTLPQKVVPPPSSCASLVPKPPPNHEQVLRRATSQKASKGSSAEGQLNGLQSSLNPAAFVPITSSTDPAHTKI---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CHB8-1", "uniprot_id": "TTLL5_MOUSE", "id": "Q8CHB8-1", "name": "Tubulin polyglutamylase TTLL5", "aln": "MPVVMARDLEETASSSEDEDLANQEDHPCIMWTGGCRRIPVLVFHAEAILTKDNNIRVIGERYHLSYKIVRTDSRLVRSILTAHGFHEVHPSSTDYNLMWTGSHLKPFLLRTLSEAQKVNHFPRSYELTRKDRLYKNIIRMQHTHGFKAFHILPQTFLLPAEYAEFCNSYSKDRGPWIVKPVASSRGRGVYLINNPNQISLEENILVSRYINNPLLIDDFKFDVRLYVLVTSYDPLVIYLYEEGLARFATVRYDQGSKNIRNQFMHLTNYSVNKKSGDYVSCDDPEVEDYGNKWSMSAMLRYLKQEGKDTTALMAHVEDLIIKTIISAELAIATACKTFVPHRSSCFELYGFDVLIDNTLKPWLLEVNLSPSLACDAPLDLKIKASMISDMFTVVGFVCQDPAQRTSNRSIYPSFESSRRNPFQKPQRTRPLSASDAEMKNLVASAREKVPGKLGGSVLGLSMEEIKVLRRVKEENDRRGGFIRIFPTSETWEIYGSYLEHKTSMNYMLATRLFQDRGNPRRSLLTGRARVSTEGAPELKVESMNSKAKLHAALYERKLLSLEVRKRRRRSGRLRAMRPKYPVIAQPAEMNIKTETESEEEEEVGLDNDDEEQEASQEESAGSLGENQAKYTPSLTVIVENSPRDNAMKVAEWTNKGEPCCKIEAQEPESKFNLMQILQDNGNLSKVQARLAFSAYLQHVQIRLTKDSGGQTLSPSWAAKEDEQMELVVRFLKRASSNLQHSLRMVLPSRRLALLERRRILAHQLGDFIGVYNKETEQMAEKKSKKKLEEEEEDGVNAESFQEFIRQASEAELEEVLTFYTQKNKSASVFLGTHSKSSKNSSSYSDSGAKGDHPET-IQEVKIKQPKQQQATEIHADKLSRFTTSSGKEAKLVYTNCSSFCSPAAVLLQRLPSSHLSSVITTSALSAGPGHHASLSQIPPAVPSLPHQPALLLSPVPDNAPPSIHSGTQNVS-PAGLPRCRSGSYTIGPFSSFQSAAH----IYSQKLSRPSSA-KAAGSCHPHKHHSGIAKTQKEGEDVSLN-RRYNQSLVTAELQRLAEKQAARQYSPASHISLLTQQVTNLNLASSVINRSSASTPPTLRPVISPSGPTWSIQPDLHASETHSSPPGSRSLQTGGFAWEGEVENNAYSKTTGVVPQHKYHPTAGSYQLHFALQQLEQQKLQSRQLLDQSRARHQAIFGSQT-LPNSSLWTMNNGPGCRISSATTGGQKPNTLPQKVVAPPNS-STLVSKPASNHKQVLRKPASQRASKGSSAEGQLNGLQSSLNPAAFMPITNSTGSLEAPQVIFARSKPLPTQSGALATVIGQRKSKSVKSGTI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B7N1-1", "uniprot_id": "A0ACD6B7N1_DANRE", "id": "A0ACD6B7N1-1", "name": "Tubulin--tyrosine ligase-like protein 5", "aln": "MPDARE-QKDESKSSSEDE----LEKQPCIAWSGVSKRIPVLLFCAEAIVSKDVAIRSVGEKYNLAFKIVRTESRLVRGILVNHGFHEVHPNSNDFNLMWTGSHLKPYLLRSLQDFQKVNHFPRSYELTRKDRLYKNIQRMQQSHGFHNFSIVPQTFVLPAEYQEFSNSFSKDKGPWIIKPVASSRGRGIYLVSNISQIPLDENILVSRYISNPLLIDDFKFDVRLYVLVTSYDPLVIYLYEEGLARFATVKYDHATANIKNQFMHLTNYSVNKKSSDYVSCDDPEVEDYGNKWSMSAMLRYLRQEGKDTTLLMGQIEDLIIKAVLSAEIHIATSCKMFVPHRCNCFELYGFDVLIDSNLKPWLLEVNLSPSLACDAPLDLKVKASMISDMFSLVGFVCQDPLLRQP-RAERAGFDLRLKIPTQKHQRQRPASSSSADPQ----TQREKHGCKHTDDTLSLSAEEMKVLRRVQEEYERRGGFIRIFPTPDTWEIYSGYLEYKTSLNAMLANKLFHRR---------SLTSRSRVQATDGISLVLGAFYTHHVVQYERKLLTLEARKKRRKPARVSRRRPPTGVKCSPSPHTSENEDGVEGQMEVQSSD---------------------------------------------------------QHTQPKVNLLHILQQGWDLSKVQARMAFSSYLHRVQLRLLAESR-ANRSPAWTQKEHDQMELVVRFLKRASSNLHQGMSVKEPSLHLCLQERQHILSQQLESFIQLYDQETKQMVESLEP---MTDEGRCINSTVFQEFILEASESDLEEVLTFYTQKNKSASVFLGTKCHRVKKSS--------EEKPETAHVNTGTSGGVENTAANSKTQSADSNTATPAGDQRQNHPTSTEN-CAAAKNTGKIKCISLRNPTQSGDCSANEAPANDTEDITRKTAVRNKK--AQLKTAYSAALECEHIILQHAVPPEPPPYLQPPPHPLANTSTWASATHTAPSISIQRPSRPSSAGHVIHSSGISKLRPGSAGVVKET-DSLMTQAQSNQQAIVSALRKLVEKQTARQYSTSSHISLLTQHLTNLNLANGLFSRGGLTLAPGV-----PHEPVRTVYKD--------TTAGNSSLRP---ACESE------SVCDGDPGSQKQRSAAGSYQLQFAIQQLQQQKLRSRQLLDQSRTRHQAVLASHAHTPAASARPVAPSSPVKQPFIRTLNQTSGILTPK--PPSSTPRDGRARKTLTHSTVHRTALSETPAAHTTTSGQHVVYDTVCAKTGLSVYSKLFHTQGSRNR--------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . : :*: ****** *.:*** *:* .:*****:* *:**::** ** :**:*:*::*****:*****.**. ********.*.*:***********:***:*.: ********************** ***::***: * *:****:***** **.**:***:****:**********:**:.* .**.*:*********.***************************************:**:.: **:***************.**************************:***:*** **.::******:::***: ***:** *****..************..***********************:*********::******** * . *. . *: : * ** ** ** *:*.*: : : *** * ...*.** **:******:** :***********.:*****..***:***:* ***.:**: * : *.: :.: . *.. ******:**.**:**:..*: ** * .*: . :.* * : ** .: *. :.*.**::***:. :***:***:***:**::**:** :* . *.:*: **.:*************.**::.: : ** :*.* **::**::** .** :*::**:**.*. . :* :* ***** :***::*********************:.: *:.. ::*** :. . :: ::: :::. . *::. : : :...: . .: :: * . :. *.. . .:*. . :: *... * . * *: * * :. .:.:. *:: **:* * *: ****** :. *. * :.* * . ** * : : **. :.: *::*.***:*****.:***.****::******..::.*.. : .* : * *. : * :..*. **:. * *.* * * .:* :.:******:**:***:****:*********:****::.*:: * :. .: .. : . : .*.. *. * .*..: .: . .*. * * . *: .: :::.** :: :.: :. . : ", "identical_positions": 592, "similar_positions": 322, "identity": "44.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-238", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZKC9-1", "uniprot_id": "D3ZKC9_RAT", "id": "D3ZKC9-1", "name": "", "aln": "MPRGRLMVLRVLIWHNFLLFARTHGPSQASWRLRSGERRDLDHRKHRSPLPSFFLPFWAFRRRPPPRWRRRGLRLKVVRCDGIGRGLRRRRPIYRKCCSFPLAGASAWEVGELPRKSSPGPPPAANMAVDSSMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSGLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNS-KVNTDGLVLRGWYNCLTLAIYGSVDRVLSHDRDSPPPPPPPPPPPQPQPT-----------------------------------------LKRSLKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPMSLP-VSGDKEED------VPHR-EDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEDDEDDVDVDEEEDEDEDDCHTVDSIPDDDEEDEEEEGEEDEEG--EGDDGYEQISSDEDGIADLERETFKYPNFDVEYT--PEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFEIEINRMKDQGPDKENSGAIEASLKLTELLDLYHE----DRGAKWVTALEEVP------SLIIKGLSYLQLKNTKQDS--LGQLVDWTMQALNLQVAFRQP-IALNVRQLKAGTKLVTSLAECG--APGVTELLQAGVISVLFDLLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRSTQSE----KSGYQKLLELILLDQTVRVVTAGSAILQKCHFYEVLSEIKRLG----------DHIAEKTSSVPNPSEPDHDTD--AVLERANPDYENEVEASMDMD-LLESSNISEGEIEKLINLLEEVFHLMETAPHTMIQPPVKSFPTIARITGPPERDDPYPVLFRYLH---SHHFLELVTLLLSIPITSAHPGVLQATKDVLKFLAQSQKGLLFFMSEYEATNLLIRALCHLYDQD----------------EEEGLQSDG-VDDAFALWLQDSTQTLQCVTELFSHFQ--------RCTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLDKNLQSLITLMEYYS-----KEALGDSKSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADE-----NNAKLQELGKWLEPLKNL-RFEINCIPNLIEYVKQNIDNLMTAEGVGLTTALRVLCNVACPPPPVEGQQ----KDLKWNLAVIQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQT--TQVIEPHDISVALNTRKLWSMHLHVQAKLLQEIVRSFSGTTCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSTSEDKEKQYTSQTTRLLALLDALASHKACKLAILHLINGTIKGDEK--------YAEIFQDLLALVRSPGDS-VIRQQCVEYVTSILQSLCDQDIALILPSPSEGPGSELEQLSNSLPSKELMAAICDCLLATLANSESTYNCLLTCVRTMMFLAEHDYGLFHLKSSLRKNSSALHSLLKRVVST-------FSKDTGELTSASLDFMRQILNSDAMGCCGDDSGLMEVESAHPPRTMSIN-----AAELKQLLQSKEESPESLFLELEKLVLEHSKEDDSLESLLDNVIGLKQMLESSGDPLPLSDQDVEPVLSAPESLQNLFNNR---TAYVLADVMDDQLKSMWFTPFQAEEIDTD----LDLVKVDLIELSEKCCS-DFDLHSELERSFLSEPSSPGRAKTTKGFKLGKHKHETFITS---SGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVPQDGIPPPKRPLKVS-QKISSRGGFSGNRGGRGAFHSQNRFFTPPASK-----GNYSRREGTRGSSWSAQN---TPRGNYNESRGGQSNFNRGPLPPLRPLSSTGYRPSPRDRASRGRGGLGPSWAST---------NSGSGGSRGKSKQPKTF--HHHH------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AIV2-1", "uniprot_id": "VIR_MOUSE", "id": "A2AIV2-1", "name": "Protein virilizer homolog", "aln": "------------------------------------------------------------------------------------------------------------------------------MAVDSSMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSGLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNS-KVNTDGLVLRGWYNCLTLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPT-----------------------------------------LKRNLKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPMSLP-VSGDKEED------VPHR-EDYFEPISPDRNSVPQEGQYSDEGEVEEEPQEEGEDDEDDVDVEEEEDEDEDDCHTVDSIPDDEEEDEEEEGEEDEEG--EGDDGYEQISSDEDGIADLERETFKYPNFDVEYT--PEDLASVPPMTYDPYDRELAPLLYFSCPYKTTFEIEISRMKDQGPDKENSGAVEASVKLTELLDLYQE----DRGAKWVTALEEIP------SLIIKGLSYLQLKNTEQDS--LGQLVDWTMQALNLQVAFRQP-IALNVRQLKAGTKLVTSLAECG--APGVTELLQAGVINVLFDLLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRSTQNE----KSGYQRLLELILLDQTVRVVTAGSAILQKCHFYEILSEIKRLG----------DHIAEKTSAVPNHSEPDQDTD--AVLERANPDYENEVEASMDMD-LLESSIISEGEIEKLTNLLEEVFHVMETAPHTMTQPPVKSFPTIARITGPPERDDPYPVLFRYLH---SHHFLELVTLLLSIPITSAHQGVLQATKDVLKFLAQSQKGLLFFMSEYEATNLLIRALCHLYDQD----------------EEEGLQSDG-ADDAFALWLQDSTQTLQCITELFSHFQ--------RCTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLDKNLQSLITLMEYYS-----KEALGDSKSKKSVAYNYACVLTLVVAQSSSGVQMLEQHAASLLKLCKADE-----NNAKLQELGKWLEPLKNL-RFEINCIPNLIEYVKQNIDNLMTAEGVGLTTALRVLCNVACPPPPVEGQQ----KDLKWNLAVIQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQT--TQVIEPHDISVALNTRKLWSMHLHVQAKLLQEIVRSFSGTTCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSTSEDKEKQYTSQTTRLLALLDALASHKACKLAILHLINGTIKGDER--------YAEIFQDLLALVRSPGDS-VTRQQCVEYVTSILQSLCDQDIALILPSPSEGPASELEQLSNSLPSKELMTAICDCLLATLANSESSYNCLLTCVRTMMFLAEHDYGLFHLKSSLRKNSSALHSLLKRVVST-------FSKDTGELASASLDFMRQILNADAMGCCGDDSGLMEVEGAHPPRTMSLN-----AAELKQLLQSKEESPESLFLELEKLVLEHSKDDDSLESLLDNVIGLKQMLESSGEPLPLSDQDVEPVLSAPESLQNLFNNR---TAYVLADVMDDQLKSMWFTPFQAEEIDTD----LDLVKVDLIELSEKCCS-DFDLHSELERSFLSEPSSPGRSKTTKGFKLGKHKHETFITS---SGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVPQDGIPPPKRPLKVS-QKISSRGGFSGNRGGRGAFHSQNRFFTPPASK-----GNYSRREGTRGSSWSAQN---TPRGNYNESRGGQSNFNRGPLPPLRPLSSTGYRPSPRDRASRGRGGLGPSWAST---------NSGSGGSRGKFVSGGSG--RGRHVRSFTR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q69YN4-1", "uniprot_id": "VIR_HUMAN", "id": "Q69YN4-1", "name": "Protein virilizer homolog", "aln": "------------------------------------------------------------------------------------------------------------------------------MAVDSAMELLFLDTFKHPSAEQSSHIDVVRFPCVVYINEVRVIPPGVRAHSSLPDNRAYGETSPHTFQLDLFFNNVSKPSAPVFDRLGSLEYDENTSIIFRPNS-KVNTDGLVLRGWYNCLTLAIYGSVDRVISHDRDSPPPPPPPPPPPQPQPS-----------------------------------------LKRNPKHADGEKEDQFNGSPPRPQPRGPRTPPGPPPPDDDEDDPVPLP-VSGDKEED------APHR-EDYFEPISPDRNSVPQEGQYSDEGEVEEEQQEEGEEDEDDVDVEEEEDEDEDDRRTVDSIPEEEEEDEEEEGEEDEEG--EGDDGYEQISSDEDGIADLERETFKYPNFDVEYT--AEDLASVPPMTYDPYDRELVPLLYFSCPYKTTFEIEISRMKDQGPDKENSGAIEASVKLTELLDLYRE----DRGAKWVTALEEIP------SLIIKGLSYLQLKNTKQDS--LGQLVDWTMQALNLQVALRQP-IALNVRQLKAGTKLVSSLAECG--AQGVTGLLQAGVISGLFELLFADHVSSSLKLNAFKALDSVISMTEGMEAFLRGRQNE----KSGYQKLLELILLDQTVRVVTAGSAILQKCHFYEVLSEIKRLG----------DHLAEKTSSLPNHSEPDHDTD--AGLERTNPEYENEVEASMDMD-LLESSNISEGEIERLINLLEEVFHLMETAPHTMIQQPVKSFPTMARITGPPERDDPYPVLFRYLH---SHHFLELVTLLLSIPVTSAHPGVLQATKDVLKFLAQSQKGLLFFMSEYEATNLLIRALCHFYDQD----------------EEEGLQSDGVIDDAFALWLQDSTQTLQCITELFSHFQ--------RCTASEETDHSDLLGTLHNLYLITFNPVGRSAVGHVFSLEKNLQSLITLMEYYS-----KEALGDSKSKKSVAYNYACILILVVVQSSSDVQMLEQHAASLLKLCKADE-----NNAKLQELGKWLEPLKNL-RFEINCIPNLIEYVKQNIDNLMTPEGVGLTTALRVLCNVACPPPPVEGQQ----KDLKWNLAVIQLFSAEGMDTFIRVLQKLNSILTQPWRLHVNMGTTLHRVTTISMARCTLTLLKTMLTELLRGGSFEFKDMRVPSALVTLHMLLCSIPLSGRLDSDEQKIQNDIIDILLTFTQGVNEKLTISEETLANNTWSLMLKEVLSSILKVPEGFFSGLILLSELLPLPLPMQT--TQVIEPHDISVALNTRKLWSMHLHVQAKLLQEIVRSFSGTTCQPIQHMLRRICVQLCDLASPTALLIMRTVLDLIVEDLQSTSEDKEKQYTSQTTRLLALLDALASHKACKLAILHLINGTIKGDER--------YAEIFQDLLALVRSPGDS-VIRQQCVEYVTSILQSLCDQDIALILPSSSEGSISELEQLSNSLPNKELMTSICDCLLATLANSESSYNCLLTCVRTMMFLAEHDYGLFHLKSSLRKNSSALHSLLKRVVST-------FSKDTGELASSFLEFMRQILNSDTIGCCGDDNGLMEVEGAHTSRTMSIN-----AAELKQLLQSKEESPENLFLELEKLVLEHSKDDDNLDSLLDSVVGLKQMLESSGDPLPLSDQDVEPVLSAPESLQNLFNNR---TAYVLADVMDDQLKSMWFTPFQAEEIDTD----LDLVKVDLIELSEKCCS-DFDLHSELERSFLSEPSSPGRTKTTKGFKLGKHKHETFITS---SGKSEYIEPAKRAHVVPPPRGRGRGGFGQGIRPHDIFRQRKQNTSRPPSMHVDDFVAAESKEVVPQDGIPPPKRPLKVS-QKISSRGGFSGNRGGRGAFHSQNRFFTPPASK-----GNYSRREGTRGSSWSAQN---TPRGNYNESRGGQSNFNRGPLPPLRPLSSTGYRPSPRDRASRGRGGLGPSWASA---------NSGSGGSRGKFVSGGSG--RGRHVRSFTR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B4B7-1", "uniprot_id": "A0A8M2B4B7_DANRE", "id": "A0A8M2B4B7-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------MAGDSAMELLFLDTFKHQNAELT-NVDVVRFPYGVLITEVRVIPPGIKAHSNLPDSRAFGETAPHAFQLDLFFNNVSKPNSPVFDRLGSLEYDENKSIIFRPNG-KINTDGLVLRGWYTCLTLAVYGTAERPHSHERDSPPPPPPPPP--QQQQI-----------------------------------------GSKRLIKLEWENEDQFNGSPPRPQPRGPRTPPGPPPPDDDDEEAMPAPGQCPVKVEN------TEHPGDDYLEPVSPERGSLPADETYSD----AEQEDDEGPADEEEDDVQSEGTEGDED----------DEEDEVGDDVTDEDG--EGDDGYEQISSDEE---DLESGAFKLPAFDLDYT--PEDLASLPTVQYDPYERELRPLQHFTPPHITRYEAELKRLKTVDIEDSSSSWAESAAKLSELLEAWGEAQGAERGAGWVTALEEVP------AFLVKGMSFLSIKDPDGQSEKLKQLVDWSCEALSLDVALAQP-IALNLRQLKAGTKLVSALADCG--AQAVQDLLEKGIVGRLLGLLFAEHVSSTLKLNVLRSLDSIISEPQGIEAMLRDRHHHDDDGTSGYQRLLDLFLLDQTVRVATAGAAILHKGHLYEVLTDLQKTASVWAERHPTVGEVAEREGSESEAGERDRESTEREGEERERETQEAERESPMDIDTLLESASLSEADLERLQGLLEELLHLLETAPHCMVQPPGKAFPTNVRITGPPERDDPYPTLYRYMH---ACHLLESLGVVLSYPATCAHIGVLQAVRELMRFLSQSQQGLLFLLSQHETINLLLRLLTPLTHLTPPSHLAPLTPLSEVEGEEAAAGGEGLMDDGFWVWLMQTLHALQGIAELN-------------GAELEDGDNPDVLATLHSLYLISFSSTGRNAVAHTFSLDNNLSCLINLIEFHA-----KDGQGDGKARKSVTYNYACMLVLLVIQTSSDLRMMEHYAAPLLLVCKADE-----NNAKLQELSKWLEPLEKL-HFDISGIPMLIDYIKQNLENLMTADGVGLVTALRVLCHIACPPATVPGQQ----KDLKWNQAIIALFSAEGMDTFIKVLQKLTSLLLLPWRLHGPMGPTAQRLMMLSVASCSLRLIRAMLTELLCGGTCEFRDVRVPSVCVTLHKILCSTPSTGRLDAEELRIQGDVTEILLTFTHAVSEQETGSEETVAGNSWSLMLKEVLNSILAAPENIYSSLSLLSELLPLPLPMQT--TQALSVQDIGVAMNTRKLWSVHLHAQARVLQEVLRCACVSSCPPLFSMLRRVCVQLCDLAAPTATLVMRTLLEQLQEEMQQEAAG------SRLIRVLALLDSLASQRACKVAMLALLSGSARSDTRSEGKVEDKLSDILPSLLAMLVLPADVGLSAQQNAELMASILQSLCDQDVSLVVSGSGEASVSEAELLANALPTKEMMTSICEGMLDVLGNTHSSYTLQLTCLRTMMFLTEHDYGLYHLKSSLKKHTTAISSLIRREITS-------FNKEFAELLSALFDFLRQILNSEAMFLRSAFYRHHHADEDMDSRSLALS-----VSDMKQLLQWKEDSGEHLLCELEKHITKLCKEDESLEALLENVVGLRQIIESSGDAQTNAEPETEPSLPAPEPLQTQFNHR---TVYVLSDVLDEQLKALWFSPFQPDEMETE----VDMVKVDLVALAQQCCT-ELDLKAELERSFLSEPSSPGHSKPSKGFRLGKHKHETFITSRYTSGRSDYVEPAKRAHIMAAPRGRGRGSFGQLSRPHDIFRQRKQNTSRPPSMHVDDFLAAEFKDVGPPTGLTLPKRPPKGGGAKPPTRGMFTGGTRGRG-FQSHTRFFTPPAPKSVLLAGNYPRREGGRGSTWSTPVTAVTHRGTYSEPRGGQSNFTR-PLPSRQPPTG-AYRLAPRDRATRGRG-TGLSWLSAGVSVGGGGGVSGGGRGQGKFSSGGSGGGRGRHVRSFTR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1R5-1", "uniprot_id": "VIR_DROME", "id": "Q9W1R5-1", "name": "Protein virilizer", "aln": "-----------------------------------------------------------------------------------------------------------------------------MADVDDGSELLFFDTFSH-EEVTDINLDLVQFPKPVFITQVRIIPLGARVQADFPGGVRLGATNPSKFDLEFFVNDLGMPAASAFENLGLLRYNQNDCIHLDCSQEKIVTDGLVLRGWYSTITLAIYGIFTNSVTEPIASPTLPCEPVGPEIANLSGEVLLQEDVLKDEWQEPMQAELLTAHKGNVSDYDPEDMEYGMSRDHYHQHAEEQEQREMRRLRRSTHSTDHSPPPPRRSHTHSESNDREYIRCSRDKGSRDWSRSPEYSSHRSRRKRSERSRSVVDEHKWPRTPPASIDSPTRPRSPDTMDYEDEDSRSHYKMQSSHYRHSSESLHRGERDRDDEDRSCTPQEQFEPILSDDEIIGDDEEDDAVDAAAIAEYERELEAAAAAAPPAIDAFEPWQKPLLVFEGDMAAHFCKELETLKLLFKKLVLQTRCENVNAFSEEHGASVD-----EREQFVYLGEQLNNQLGYLAQHYKRRNFVLQQFFGNDELHLRQAANVLQIALSFQAACMQPQPAFKIRHIKLGARMAELLGSSEELFQHLLKEHKFDIFEAVFRLYHEPYMALSIKLQLLKAVYALLDTRMGIEHFMGAKNNG-------YQMIVEAIKTAKLTRTKYALQAIIKKLHLWEGLESVQIWCR----------RLFVDRIIIPGNRDQMEDTVITCQQIEFAFEMLMDALFSSQLSYLQPRRFLPVSKKFEVVTDPTAQRSFGNALQSYLGQNSLAESLLVMLANCKELPATTYLSMLDLMHTLLRSHVGIDYFVDDAFPVTQTIVAILLGLDEVPRNPEEKEEKAEKSDAEDKAMEVENEAVEAGGEKPTPPTADEEGKPVAAPISVPAPAAAPQVRPRPILRPVLPRLARLGIEMSYKVQTRYHLDAIAYAAAAPEYDAVKLATHMHAIYSQTCDPAGRQHTVEVLGLNNNLKIFMDLIKKEQRLQTQRQLSSPGTKYKSPVLSYAVDMVDACVRYCEQLDYLIEHGGVILELAKNHETFEPSVSAVLQEMYVYMKPLEAINVFVYDDIMPLVEVIGRSLDYLTTFPGD-LIMAMRILRYLSISKPLAGQKAPPVTEELKHRFVALQLYAADGVQLCIQIMERLCAYFEQPG-AHAPALMTIQGVHCCQIMLPTLQILRELLSYAILCRDGTYKDLTAIDHLVKVYYLLYYFPTRCQAGPEVEQCKMEVVQTLLAYTQPNEQD----EESLHKSLWTLMIREVLKNVDG-PAHFIPGLKLLAELLPLPLPMPQPLCDQLQQQHKQRLITERKLWSAHLHPQSGQIAKLVEALAPSSFPQLSELLQRVCMQLSDLAPNMTLLIAKTITELLCNEYQTSNCIP----TTNLERLLRFSTRLCAFAPLKSSMLSILSG--------------KFWELFQSLLALN----EFNDVVSNCQEAVHRILDSFLDSGISLIS---HKSTASPALNLAAALPPKELIPRIIDAVFSNLTSVEVTHGISILAVRNLVILTEHDFTFYHLAQLLKQKITEFQAWMERVILHNETVEYNANIESLILLLRSLTQIEPPPAMSAMPHRTLKLGATELAQLVEFQDIELAKPPVLSRILTVMEKHKAVANEAALSDLKQLILLQASKQEILAGTSTETPPEAEGEANPSASSCSASLTVEPYLPQAEGIVTQYEARPIFTRFCATAENAQLTARYWLDPLPIELIEDMNEPIYERIACDLTDLANVCLNPDLNVAGDSKRVMNLSGSPQSNREMTPTAPCFRTRRVEVEPATGRPEKKMFVSSVRGRGFARPPPSRG-----------DLFRSRPPNTSRPPSLHVDDFLALETCGAQPTGPTGYNKIPSMLR---GSRVGRNRGSRISAAAAFRQKKMMRIGSPS-----------------SWAESP------GSYRSASDSHFSSSD------SHYSSPHYSGRPRGRGLRSRPSYLR-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. ****:***.* . ::*:*:** * *.:**:** * :.::.:*.. * * * *:*::*.*::. * :..*:.** *.*::* .* : . *: **********. :***:** . :. **. * * : .: : . *:::* : * ..:.. .* ** .. ..:. : :. . .. . .:*. : . . . : * :.* ... . :. .. . **: :: :* * **:: * * . :* * *: .. *.:: ** * : : *:. :* . . * ::* : . :* *:: : * .:: : :. * * .: **.::.* ** *:::*::* *:::. *... : : .:. :: * . ::: ::**: :::: :::. *:* :: : ** ::: : : .*. * **::* *::* * .:: .: . : .:: . : . ::. * :. .. .: . :: : * . . .* : :* *. : : * * : .:* . :: : :.:: :: :: :: . : . . . . : . : : : : * .: :* :* : ...**. . ..:.*::**. :: *:: :: . .. ** . .** : : .. : : .:.. :* :.* .* .* ***: :::**: : * . * *:: : :.:: * * * * *:*:* :: . . . : ::** . . : *::*:*:: *:::::* : : * * * : : .: :* ::: :*: : ::*: . . *.:: :* * : ..: : : :: : **::*: .:. **:: . *:**::***..: * : ..* **:********* : :. :. :. ***** *** *: : :::.. . :: : :*:*:*:**.***. : *: :*: : : :: * :. *:* : *.: . * ::* ::.* ::: .***: : .: * : **:*: *..::*: :.. * *: :** **::. * : :: * . . :: : .:*.:::*:***: ::** . *::: : : : :.* : . : * : :. .:: . : : : :. : : * : * : :*:: : ...:: * . .. : ... . :. .** *. .* : . :: * * : : : *: *: : :: : : ** *:: * . :::: .: :* : . *. .. : : : :: . .: . :. ::...: . .* .** *:**.* *******:*****:* * . * * * . * *. . . :.::: :.. :*: *.* .. ..: . . :. * **.*. *.* ", "identical_positions": 300, "similar_positions": 593, "identity": "14.15%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-240", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9P0K8-1", "uniprot_id": "FOXJ2_HUMAN", "id": "Q9P0K8-1", "name": "Forkhead box protein J2", "aln": "MASDLESSLTSIDWLPQLTLRATIEKLGSASQAGPPGSSRKCSPGSPTDPNATLSKDEAAVHQDGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFRKVPRPRDDPGKGSYWTIDTCPDISRKRRHPPDDDLSQDSPEQEASKSPRGGVAGSGEASLPPEGNPQMSLQSPTSIASYSQGTGSVDGGAVAAGASGRESAEGPPPLYNTNHDFKFSYSEINFQDLSWSFRNLYKSMLEKSSSSSQHGFSSLLGDIPPSNNYYMYQQQQPPPPQQQQQQQQPPQPPPQQSQPQQQQAPAQGPSAVGGAPPLHTPSTDGCTPPGGKQAGAEGYGPPPVMAMHPPPLQHGGYHPHQHHPHSHPAQQPPPPQPQAQGQAPINNTGFAFPSDWCSNIDSLKESFKMVNRLNWSSIEQSQFSELMESLRQAEQKNWTLDQHHIANLCDSLNHFLTQT-------------GHVPPQGGTHRPPAPARIADSCALTSGKQESAMSQVNSYGHPQAPHLYPGPSPMYPIPTQDSAGYNRPAHHMVP--------RPSVPPP---GANEEIPDDFDWDLIT-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FA97-1", "uniprot_id": "E7FA97_DANRE", "id": "E7FA97-1", "name": "Forkhead box protein G1", "aln": "MTSELDSSLTSIDWLPQLGISTLRSGKERVERKKERGREKDIPLIPALSP---------GSNSKVKPPHSYATLIAMAISSAPEMKLSLNDIYTWISDTFPYYCRAGRGWKNSIRHNLSLNKCFRKVPRPQSDPGKGSYWTMDVPPESTQ----PRGVKRPYTDDEHVVTPFPETQLPANQPEPLPPQPDTKSTFPPPP----------CKQRPAIPVPSSLPSNPHADPPLR-------FSFADLNLPDLYNSFQSLCRSMREKVTS--QSDVSTLLG------------------LTHDSTPLHTPTLPPLSPCPNPNINQFINPNST----HIPNLNTNGNFNPNAPHSFIPTLNPNQNSSIHP-------------NSSTEPDKVLPN----------------VVPADWFSNPDSLRESFRIASSLDWANIDLSCHPDLLESMRQAELRDWALDPALFTSLCDSLNRFFTHKGLIGSSSGGPSSFGHMAPPSVNMPPTNPPTLSSLTQPSPLIYPSQLPPGSGEAPLQGPRRNLTPLAQNQTTQTPGGLQPTTSQPMTPNALHTQPLTPSARPPLKTGISEEIQDDFDWDSLIE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*:*:************ : : . ..: * .:. . .. .* . :.. ** :******: **.*:* *::*.:** **.*.**** .** **********************:.*********:*. *: :: * . . . . *: .: *. :... .***: :.: :: .*. . : *:.. :* ..... *** **::::*: ** **:.* :** ** :* * ..*:*** ::. :.* ** .. *: : .*.:. : . .*:* *.. :: .* ::** :. :.* : * ..*:** ** ***:***::.. *:*:.*: * ..:*:**:**** ::*:** ::.******:*:*:. **:.* . . *. *. ::. :. * :. .. . *.*: * . . .. .:: *.* **. ** * .*** ****** : ", "identical_positions": 176, "similar_positions": 167, "identity": "29.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-243", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R685-1", "uniprot_id": "M0R685_RAT", "id": "M0R685-1", "name": "Serine/threonine-protein kinase ULK4", "aln": "MENFVLYEEIGRGSRTVVYKGRRKGTINFVAILCTEKCKRPEITNWVRLTHEIKHKNIVTFHEWYETSNHLWLVVELCTGGSLETVIAQDQNLPEDVVREFGVDLVTGLHHLHRLGILFCDLSPGKILLEGPGTLKFSNFCLAKVEGESLEEFFALVAAEE-GGGDSGEN-TLRKSMKTRVRGSLIYAAPEIVTGTEFSVTSDLWSLGCLLYEMFSGRPPFFSETMSELVEKILYEDPLPPIPKDSSFPKASSDFINLLDGLLQKDPQKRLSWEGVLQHPFWKDALRRED-SDSVSEDSTFSSRNVMECSGPHDSRELLQ-----------SPKNGQAKGQKGAHRLSQSFRLENPTELRPKSIMGGQLNESIFLLSSRPTPRTSAMVELNPGEGEDPSSPQKTSPLSKMTSGHLSQGALESQMRELIYTDSDLVITPIIDNPKIMKQPAIKFDPKILHLPAYSVEKLLALKDQDWSDFLQQLCSHVDSSEKS----TGALRAKLNLLCYLCVVATHKEVATRLLHSPLFQLLIQHLRIAPNWDIRSKVARVVGMLALHTAELQESVPVIEAITLLTELIRENFRSGKLKQCLLPTLGQLLYLVATQEEKTQHSRECWSVPLAAYTVLMRCLREGEERVVNHMAAKIIENVCTTFSAQAQGFTTGEIGPVLWHLFRHSTVDALRITAISALCRITRQSPTAFQNVIEKVGLNAVISSLASAICKVQQYMLTLFTAMLSCGIHLQRLIQEKDFVSTVIRLLDSPSTPIRAKAFLVLLYVLIHNRDMLLLSCQARLVMYIERDSRKTSPGKELQSGNEYLARCLDLLIQHMVQESPRILGDILNALANVSGRKHPSTVQGKQLKMCLPMMPVVLHLVMSQVFRPQVVTEEFLFSYGTILSHIKSIDLGETNIDGAIGIVASEEFIKITLSAFEAVIQYPVLLADYRATVVDYILPPLVSLVQSQNVEWRLFSLRLLSETTTLLVSQEPEDGDE-----------EASCDSDSGLLALIRDELLPQYEHILMEPDPVPAYALKLLVAMTEHNPAFTRLVAESKLVPLIFEVILEHQESILGNTMQSVIALLNNLVAYKDSNMQLLYEQGLVGHVCNMFTETATLCLDRDNKTNTEPAATLLASLLDILLGMLTYTSRIVRQALQAQKSGSRGDTQAAEDLLLLSKPLTDLISLLIPLLPSEDPEISEVSSKCLSILVQLYGGENPESLSPENLVTFADLLMAKEDPKDQKLLLRILKRMVTSNEKLLESLRNTGSLLQALERLAPAHSSPVDTVVASLALDLLQAVGH----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3V129-1", "uniprot_id": "ULK4_MOUSE", "id": "Q3V129-1", "name": "Inactive serine/threonine-protein kinase ULK4", "aln": "MENFVLYEEIGRGSRTVVYKGRRKGTINFVAILCTEKCKRPEITNWVRLTHEIKHKNIVTFHEWYETSNHLWLVVELCTGGSLETVIAQDENLPEDVVREFGVDLVTGLHHLHRLGILFCDLSPGKILLEGPGTLKFSNFCLAKVAGESLEEFFALVAAEE-GGGDSGEN-ALKKSMKTRVRGSLIYAAPEIVKGTEFSVTSDLWSLGCLLYEMFSGKPPFFSETVSELVEKILYEDPLPPIPKDSSFPKASSDFLNLLDGLLQKDPQKRFSWEGVLQHPFWKDALRGED-SGWASEDSPFS-RNVMECSGPHDSRELLQ-----------SPKNGQAKGQKAAHRLSQSFRLENPTELRPKSIMGGQLNESIFLLSSRPTPRTSAMVELNPGEGEDPSSPQKTSPLSKMTSGHLSQGALESQMRELIYTDSDLVITPIIDNPKIMKQPAIKFDPKILHLPAYSVEKLLVLKDQDWNDFLQQVCSQIDSSEKS----TGALRAKLNLLCYLCVVATHKEVATRLLHSPLFQLLIQHLRIAPNWDIRSKVARVVGMLALHTTELQENVPVIEAITLLTELIRENFRSGKLKQCLLPTLGQLLYLVATQEEKNQHSRDCWAVPLAAYTVLMRCLREGEERVVNHMAAKIIENVCTTFSAQAQGFTTGEIGPVLWHLFRHSTVDALRITAISALCRITRQSPTAFQNVIEKVGLNAVISSLASAICKVQQYMLTLFTAMLSCGIHLQRLIQEKDFVSTVIRLLDSPSTPIRAKAFLVLLYILIHNRDMLLLSCQARLVMYIERDSRKTSPGKEQQSGNEYLARCLDLLIQHMVQEPPRILGDILNALANVSGRKHPSTVQGKQLKMCLPMMPVVLHLVMSQVFRPQVVTEEFLFSYGTILSHIKSIDLGETNIDGAIGIVASEEFIKVTLSAFEAVIQYPVLLADYRSTVMDYILPPLVSLVQSQNVEWRLFSLRLLSETTTLLVSQEPEDGDE-----------EASCDSDSSLLALIRDELLPQYEHILMEPDPVPAYALKLLVAMTEHNPAFTRLVEESKLVPLIFEVILEHQESILGNTMQSVIALLNNLVAYKDSNMQLLYEQGLVGHVCNMFTETATLCLDRDNKTNTEPASTLLASLLDILLGMLTYTSRIVRQALQVQKSGSRGDTQAAEDLLLLSKPLTDLISLLIPLLPSEDPEISEVSSKCLSILVQLYGGENPESLSPENMVTFANLLMTKEDPKDQKLLLRILKRMVTSNERLLESLKNTGSLLQALERLAPAHRLRGPWAGISCALFQQRAAAQGIPELPPYGIPCCGPSHKRVTGVKLYPC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96C45-1", "uniprot_id": "ULK4_HUMAN", "id": "Q96C45-1", "name": "Inactive serine/threonine-protein kinase ULK4", "aln": "MENFILYEEIGRGSKTVVYKGRRKGTINFVAILCTDKCKRPEITNWVRLTREIKHKNIVTFHEWYETSNHLWLVVELCTGGSLKTVIAQDENLPEDVVREFGIDLISGLHHLHKLGILFCDISPRKILLEGPGTLKFSNFCLAKVEGENLEEFFALVAAEE-GGGDNGEN-VLKKSMKSRVKGSPVYTAPEVVRGADFSISSDLWSLGCLLYEMFSGKPPFFSESISELTEKILCEDPLPPIPKDSSRPKASSDFINLLDGLLQRDPQKRLTWTRLLQHSFWKKAFAGAD-QESSVEDLSLS-RNTMECSGPQDSKELLQ-----------NSQSRQAKGHKSGQPLGHSFRLENPTEFRPKSTLEGQLNESMFLLSSRPTPRTSTAVEVSPGEDMTHCSPQKTSPLTKITSGHLSQQDLESQMRELIYTDSDLVVTPIIDNPKIMKQPPVKFDAKILHLPTYSVDKLLFLKDQDWNDFLQQVCSQIDSTEKS----MGASRAKLNLLCYLCVVAGHQEVATRLLHSPLFQLLIQHLRIAPNWDIRAKVAHVIGLLASHTAELQENTPVVEAIVLLTELIRENFRNSKLKQCLLPTLGELIYLVATQEEKKKNPRECWAVPLAAYTVLMRCLREGEERVVNHMAAKIIENVCTTFSAQSQGFITGEIGPILWYLFRHSTADSLRITAVSALCRITRHSPTAFQNVIEKVGLNSVINSLASAICKVQQYMLTLFAAMLSCGIHLQRLIQEKGFVSTIIRLLDSPSTCIRAKAFLVLLYILIYNREMLLLSCQARLVMYIERDSRKTTPGKEQQSGNEYLSKCLDLLICHIVQELPRILGDILNSLANVSGRKHPSTVQVKQLKLCLPLMPVVLHLVTSQVFRPQVVTEEFLFSYGTILSHIKSVDSGETNIDGAIGLTASEEFIKITLSAFEAIIQYPILLKDYRSTVVDYILPPLVSLVQSQNVEWRLFSLRLLSETTSLLVNQEFGDGKE-----------KASVDSDSNLLALIRDVLLPQYEHILLEPDPVPAYALKLLVAMTEHNPTFTRLVEESKLIPLIFEVTLEHQESILGNTMQSVIALLSNLVACKDSNMELLYEQGLVSHICNLLTETATLCLDVDNKNNNEMAAPLLFSLLDILHSMLTYTSGIVRLALQAQKSGSGEDPQAAEDLLLLNRPLTDLISLLIPLLPNEDPEIFDVSSKCLSILVQLYGGENPDSLSPENVEIFAHLLTSKEDPKEQKLLLRILRRMITSNEKHLESLKNAGSLLRALERLAPGSGSFADSAVAPLALEILQAVGH----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T5H9-1", "uniprot_id": "A0AB32T5H9_DANRE", "id": "A0AB32T5H9-1", "name": "", "aln": "MENFILYEEIGRGSRSVVYKGRRKGSIHFVAIICSEKHKRPELTNHVRLAHDIKHDNVVAFYEWYETSNHLWMVVEMCTGGSLAALIAQDECLSEDVVREFSIDLVKGLKYIHDSGIIVSDLTPAKILLDGPGTLKYSNFCLAKAQGESLEEFFSLVMAEETGLGESKENNSSPRNIKNRIKGSPVYCSPEVLRGSETNVDSDLWALGCVLYEMFTGKPPFVSESMTGLVDLILNEDPPPLRPKEPASSQPSPDFENLVMGLLQKDPVLRLSWDPLLSHPFWRDAFLEAHNSKGKPQDDVSSISRVFGDWSFKKGTEVFQICLHLAPVAPQTAEEAQTAPADPASPNSKSFTLDNVIEFRPKSALDIDAREAIFLLSSRPTPRTSTARETEDSRAEIHES-------SVMAE---EQSDLNTCIKSLLYTDCDLTVTPIMDNPKILKTAPVRFDPKTLCVPAHSAERLSCLSSEDWSQFLQQVCAVLESVDRAGSANATAPRAKLNLLCYLCTVCNHRDTATRLIHSELFPVLVQQMRQAPNWDIRSKVMRAIGLLASHCTELRDHAPVSEAVAMFTELIRENFRSSKLKQCLIPPMGELLYLIATQEEKKERPGGLWVVPAAAYTVLMRCLREGEDLVVNHMAAKTIENVCSRESQSAQGFITAEVGPALWYLFTHSTVDALRVSAISALCKITRQSAGAFQSVIDKVGLPSILSCLVSGISRVQQHMLTMFAAMLASGAHSHRLVQDRDFVMKIIRSLESPSSVIRAKAFLVLLQVLMNNREMLLLCCNSRLVMYIERDVRKATPGKEQQSGNEYLSKCLTLFIRHTVRELPAILDDILSVLGSIVGRKHPSPTQSRQLKQSLPMMAVVLHLLTSQIFRPQVVTEAFLIKFGKLLNHITSIDSNETSLGSAIGQASSEELIRNTLSAVEAISQHPALLSLYPFIVVDLIVPPLASLAFSKNVEWRIVSLRVLSEITLLLLSQDEVEERERAGEGEREWEGEGNISSNTRLLTLISEALLPQYETLLLEPDPVPVYALKLLVSLTEHSSPISRLVRESRLLPAIFQVIEEHQSNSVGGTMQNAVALLCNLIGQKGTDLRPFYQQGVIEVVCNLFVEVSGVYLEREMQSGLKSCSSLLVSLLDIIHILLKNLSSVVRMALQR--SDSNEDAEAAEELLLINKPLTDLNNLLIQLLTCDDSEVYEEASHCVSLLAQLYGGEGADRLQPEELLSLAHALQTHTEPRQQKLLLRVLKRLMSAVGSSCWGSSEGQILVHTLQKLMLLNRPQSDMTVESLAADILKSIGSHTETLSPGI-------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:*********::*********:*:****:*::* ****:** ***:::***.*:*:*:**********:***:****** ::****: *.*******.:**:.**:::* **:..*::* ****:******:*******. **.*****:** *** * *:. ** :.:*.*::** :* :**:: *:: .: ****:***:*****:*:***.**::: *.: ** *** * **:.: .:.*.** **: ****:** *::* :*.*.**:.*: . . :* * ..: . :.. *::* ..:. *: . . .:** *:* *:**** : : .*::************: * . .. * : ::. .* *:: ::.*:***.**.:***:*****:* ..::**.* * :*::*.::* *..:**.:****:*: ::* ::: * ***********.*. *::.****:** ** :*:*::* *******:** :.:*:** * :**:: .** **:.::*********..******:*.:*:*:**:******.:.. * ** **************: ******** *****: * .:*** *.*:** **:** ***.*:**::*:****:***:*. ***.**:**** :::..*.*.*.:***:***:*:***:.* * :**:*::.** .:** *:***: ********** :*: **:****.*::********* **::**** *******::** *:* * *:* * **.***. *..: ******..* :*** .**:*.*****: **:******** **:.:*.:*.**.*:* .**.:..*** .:***:*: ****.**: *:* ** * *:* *:***.**. *:*****:.***:*** * **:.*: : * :.. .*:: **:** : ****** :*:******.*******::***...::*** **:*:* **:* ***.. :*.***..:*** **:. *.:::. :*:**:: :**::.*.: : *: : :.. : .:.** *****: :*. * :** *** *.* *.:***:***:.:***** .*** **. :*.*: : :*:*:*:*.******..: *.**:: :*. * :: :*::******:*:*:::: . : *:::*::* . . * :: . ", "identical_positions": 650, "similar_positions": 393, "identity": "48.76%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-245", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P98175-1", "uniprot_id": "RBM10_HUMAN", "id": "P98175-1", "name": "RNA-binding protein 10", "aln": "MEYERRGGRGDRTGRYGATDRSQDD--------GGEN---------RSRDHDYRDMDYRSYP-----------REYGS----------------QEGK-HDYDDSSEEQS--------------AEDSYEASPGSETQRRRRRRHRHSPTG-------------------PPGFP----RDGDYRDQDYRTEQGEEEEEE--EDEEEEEKASNIVMLRMLPQAATEDDIRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEANQHSLNILGQKVSMHYSDPKPKINEDWLCNKCGVQNFKRREKCFKCGVPKSEAEQKLPLGTRLDQQTLPLGG-RELSQGLLPLPQPYQAQGVLASQALSQGSEPSSENANDTIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAFIQLSTIVEAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDMASNEGSRISAASVASTAIAAAQWAISQASQGGEGTWATSEEPPVDYSYYQQDEGYGNSQGTESSLYAHGYLKGTKGPGITGTKGDPTGAGPEASLEPGADSVSMQAFSRAQPGAAPGIYQQSAEASSSQGTAANSQSYTIMSPAVLKSELQSPTHP-SSALPPATSPTAQESYSQYPVPDVSTYQYDETSGYYYDPQTGLYYDPNSQYYYNAQSQQYLYWDGERRTYVPALEQSAD--GHKETGAPSKEGKEKKEKHKTKTAQQIAKDMERWARSLNKQKEN---FKNSFQPISSLRDDERRESATADAGYAILEKKGALAERQHTSMDLPKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPEREEKLTDWQKLACLLCRRQFPSKEALIRHQQLSGLHKQNLEIHRRAHLSENELEALEKNDMEQMKYRDRAAERREKYGIPEPPEPKRRKYGGISTASVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRVRGSGLGARGSSYGVTSTESYKETLHKTMVTRFNEAQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99KG3-1", "uniprot_id": "RBM10_MOUSE", "id": "Q99KG3-1", "name": "RNA-binding protein 10", "aln": "MEYERRGGRGDRTGRYGATDRSQDD--------SGEN---------RSRDHDYRDMDYRSYP-----------REYGS----------------QEGK-HEYDDSSEEQS--------------AEDSYEASPGSETQRRRRRRHRHSPTG-------------------PPGFP----RDGDYRDQDYRTEQGEEEEEE--DEEEEEEKASNIVMLRMLPQAATEDDIRGQLQSHGVQAREVRLMRNKSSGQSRGFAFVEFSHLQDATRWMEANQHSLNILGQKVSMHYSDPKPKINEDWLCNKCGVQNFKRREKCFKCGVPKSEAEQKLPLGTRLDQQALPLGG-RELSQGLLPLPQPYQAQGVLTSQALSQGSEPSSENANDTIILRNLNPHSTMDSILGALAPYAVLSSSNVRVIKDKQTQLNRGFAFIQLSTIVEAAQLLQILQALHPPLTIDGKTINVEFAKGSKRDMASNEGSRINAASVASTAIAAAQWAISQASQGGESAWAAPEEPPVDYSYYQQDEGYGSSQGTDS-LYAHGYLKNSKGPGMTGTKGDPAGTGPEASLEAGADSVSLQAFSRAQPGAAPGLYQQSAEGSSGQSTATNSQSYTIISPAVLKAELQSPTQPSSSAFPPATSPTAPEAYSQYPVPDVSTYQYDETSGYYYDPQTGLYYDPNSQYYYNAQSQQYLYWDGERRTYIPALEQSAD--GHKDTGASSKEGKEKKEKHKTKTAQQIAKDMERWARSLNKQKEN---FKNSFQPISALRDDERRESATADAGYAILEKKGALAERQHTSMDLPKLASDDRPSPPRGLVAAYSGESDSEEEQERGGPEREEKLTDWQKLACLLCRRQFPSKEALIRHQQLSGLHKQNLEIHRRAHLSENELEALEKNDMEQMKYRDRAAERREKYGIPEPPEPKRRKYGGISTASVDFEQPTRDGLGSDNIGSRMLQAMGWKEGSGLGRKKQGIVTPIEAQTRVRGSGLGARGSSYGVTSTESYKETLHKTMVTRFNEAQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1R9N7-1", "uniprot_id": "F1R9N7_DANRE", "id": "F1R9N7-1", "name": "", "aln": "MDYERRG-RGDRMGRYGKASDDHDYRDMDYRGYGQENGLGLTSSLANTRQHDGSSDGPKDFPSGNFSNNRPGFRQKGNRASEVGKDQNIHSRFQHDGKDYEFEAETEARRRDAQSLRSRPKVFLDQQTPDEEEGDEDNTWGRLRGRQNSQGEYNAEWRAEEDKLNRNLKHKQGFPDQVQSQSKMKDGSFDPEEAEVHDQDYRSDADALQKPSNIVMLRMLPLNATVNEIRARLQEQGIQPREVRLMRNKSSGQSRGFAFVEFNHLQEASRWMETNQKVLTILGQRVSMHYSDPKPRANEDWLCNKCGVQNFKRREKCFKCGVPKSEAELKLPLVP----KILPLCQLKDSTQGLLPLPAIFQTATSILN--LSSSPQPS-EAANDTLILRNLGPHTTLEAILSALAPFATLSPSNVRLIKDKQTQLNRGFAFLQLTTIVEASQLLQILQALQPPLSIDGKLISVEFAKGSKRDVFLTDGSRVSVATVASTAIAAAQWAVSQTASGAQSG---------DLSVLQQGAAAFSQDGSQSRTAETQAFKGPVTTLLT--PADRAVAG-----ETTAASILTHAASQIQL------------VSSTPSTQDRQTSVEIIG----------KPQP-AACVQPATPGTALECQ-QYPDPDVSTYQYDESSGYYYDPFTGLYYDPNSQYYFNPHTQQYMYWDGEKHTYVPAPSQSEDSAGNELSGAPN-SSKDKKDKPKNKSAQQIAKDMERWAKSLNRQKENGRSVNTNPRLMTHSRSDDRRESASADAGYAVLEMKGALLERPQILMEQIKHP-EDRESPPQALLAGCSVETDSEDES----SEKQERLTDWCKLACLLCRRQFPSKEALIRHQQLSELHRQNLEQKRSRTTVSNTQEGSE----TELKYRDRAAERREKGIIPQQPDAKKRRISPVSAAGFQMLP-------------------GRTEKGFFIRN-----VPVE-----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:***** **** **** :. .:* . ** .:*:** . . :.:* *: *. ::** :::: .:* : ::: : . *.* : * * *:.. * *** :.. :* .: .*:.* .::: .: : :*.********** ** ::**.:**.:*:*.**********************.***:*:****:**: *.****:**********: ******************************* **** . : *** :: :******* :*: : . **...:** * ****:*****.**:*:::**.****:*.**.****:**************:**:*****:*********:***:**** *.**********: .:***:..*:************:**::.*.:. * * **. . ..:*::* :*.. . :* .* : :* *. * *: :* *: * ** .* .. * *:. .:* ::.. ***. ** *. *** **********:******* ************:*.::***:*****::**:** .** * *:: :**.. ..*:**:* *.*:************:***:**** .:.. : :: *.*:*****:******:** **** ** : *: * . :** ***:.*:*. * *:***:*. .*::*:**** ************************ **:**** :* .* *. * ::************ **: *:.*:*: . :*:*..:: * .* . : *: .*:* ", "identical_positions": 451, "similar_positions": 218, "identity": "44.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-25", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JTY4-1", "uniprot_id": "NFAC3_RAT", "id": "A0A0G2JTY4-1", "name": "Nuclear factor of activated T-cells, cytoplasmic 3", "aln": "MTTANCGAHDELDFKLVFGEDGAPTPVSQVSRPADLEPDDCASIYIFNVDPPPSTLNSSLGLPHHGLLQSHSSVLSPSFQLQGFKNYEGTDDISESKYSSLSGPKPFECPSIQITSISPNCHQETDAHEDDLHVNDPEREYLERPSRDHLYLPLEPSYRE-SSLSPSPASSVSSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPG--------------------GCP------GEESWH--QQYGPG---HSLSPRQSPCHSPRSSITDENWLSPRPASG---PSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLTAPVHTGSGLSPAPFPFQYCVETDIPLKTRKT-----SDDQAAILPGKLEVCSDDQGSLSPSRETSVDDGLGSQYPLKKDSSGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPLDWPLPTHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYSEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMIVTGSNFLPESKIIFLEKGQDGRPHWEAEGKIIREKCQGGHIVLEVPPYHNPAVTSAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEQREDTDLSSVPSLPVPHSAQTQRPSSDTGHPHDSALSAPRSLICPVQPAYASMITSTHLPQLQCRDEGAGKEQHIIPSSVMHQPFQVTPTSPMGSSYQSIQTN-MYNGPTCLPMNPASSQEFDPVLFQQDAALSNLVNLGCQPLSPIPFHSSNSDATGHLLAHSPHSVQTPPHLQSMGYHCSSAGQRSLSSPVAAQVTGQPSSHLQPITYCPSHPGSATAASPAASHALSSSPISGPPSPQLQSMPYQSPSSGTASSPSPVTRMHSGQHSTQAQSTGQGGLSVPSSLVCHSLCDPASFPPGGAAVSIKPEPEDQEPNFATIGLQDITLDDVNEIIGRDMSQITVSQGPEVIRDAPLPGPESPDVMSSNSAQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97305-1", "uniprot_id": "NFAC3_MOUSE", "id": "P97305-1", "name": "Nuclear factor of activated T-cells, cytoplasmic 3", "aln": "MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHG-LPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQFTSISPNCQQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRE-SSLSPSPASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPG--------------------GCP------GEESWH--QQYGSG---HSLSPRQSPCHSPRSSITDENWLSPRPASG---PSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLTAPVHTGSGLSPAPFPFQYCVETDIPLKTRKT-----SEDQAAILPGKLEICSDDQGNLSPSRETSVDDGLGSQYPLKKDSSGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPLDWPLPTHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYSEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMIVTGSNFLPESKIIFLEKGQDGGPHWEVEGKIIREKCQGAHIVLEVPPYHNPAVTSAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEQREDTDLPSVPSLPVPHSAQAQRPSSETGHPHDRAMSAPGGLLCQVQPAYTSMVASTHLPQLQCRDEGAGKEQHIATSSVMHQPFQVTPTSPIGSSYQSIQTS-MYNGPTCLPVNPASSQEFDPVLFQQDAALSSLVNLGCQPLSPIPFHSSNSDATGHLLAHSPHSVQTPPHLQSMGYHCSNAGQTALSSPVADQITGQPSSHLQPITYCPSHPGSATAASPAASHPLASSPISGPSSPQLQPMPYQSPSSGTASSPSPTTRMHSGQHSTQAQSTGQGGLSVPSSLVCHSLCDPASFPPGGATVSIKPEPEDQEPNFATIGLQDITLDDVNEIIGRDMSQISVSQATEVMRDTPLPGPASPDLMTSHSAH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12968-1", "uniprot_id": "NFAC3_HUMAN", "id": "Q12968-1", "name": "Nuclear factor of activated T-cells, cytoplasmic 3", "aln": "MTTANCGAHDELDFKLVFGEDGAPAPPPPGSRPADLEPDDCASIYIFNVDPPPSTLTTPLCLPHHG-LPSHSSVLSPSFQLQSHKNYEGTCEIPESKYSPLGGPKPFECPSIQITSISPNCHQELDAHEDDLQINDPEREFLERPSRDHLYLPLEPSYRE-SSLSPSPASSISSRSWFSDASSCESLSHIYDDVDSELNEAAARFTLGSPLTSPGGSPG--------------------GCP------GEETWH--QQYGLG---HSLSPRQSPCHSPRSSVTDENWLSPRPASG---PSSRPTSPCGKRRHSSAEVCYAGSLSPHHSPVPSPGHSPRGSVTEDTWLNASVHGGSGLGPAVFPFQYCVETDIPLKTRKT-----SEDQAAILPGKLELCSDDQGSLSPARETSIDDGLGSQYPLKKDSCGDQFLSVPSPFTWSKPKPGHTPIFRTSSLPPLDWPLPAHFGQCELKIEVQPKTHHRAHYETEGSRGAVKASTGGHPVVKLLGYNEKPINLQMFIGTADDRYLRPHAFYQVHRITGKTVATASQEIIIASTKVLEIPLLPENNMSASIDCAGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHIPQPSGKVLSLQIASIPVECSQRSAQELPHIEKYSINSCSVNGGHEMVVTGSNFLPESKIIFLEKGQDGRPQWEVEGKIIREKCQGAHIVLEVPPYHNPAVTAAVQVHFYLCNGKRKKSQSQRFTYTPVLMKQEHREEIDLSSVPSLPVPHPAQTQRPSSDSGCSHDSVLSGQRSLICSIPQTYASMVTSSHLPQLQCRDESVSKEQHMIPSPIVHQPFQVTPTPPVGSSYQPMQTNVVYNGPTCLPINAASSQEFDSVLFQQDATLSGLVNLGCQPLSSIPFHSSNSGSTGHLLAHTPHSVHTLPHLQSMGYHCSNTGQRSLSSPVADQITGQPSSQLQPITYGPSHSGSATTASPAASHPLASSPLSGPPSPQLQPMPYQSPSSGTASSPSPATRMHSGQHSTQAQSTGQGGLSAPSSLICHSLCDPASFPPDGATVSIKPEPEDREPNFATIGLQDITLDDVNEIIGRDMSQISVSQGAGVSRQAPLPSPESLDLGRSDGL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IZ64-1", "uniprot_id": "A0AC58IZ64_DANRE", "id": "A0AC58IZ64-1", "name": "", "aln": "MSSNYS---EELDFRLIFGESSFSHTESRSDDDANCYP-LYPSEPHFPTEQQDNCTNQPYGTPNPG---SVQPMESPS--------------------------RVFDCPSIQITSIPANCLQDPGTQQLDQSTGACAEVGAGSLSRDQLFLPLDASYRDTSSLCPSPCSSLSSRSWLSDASSCESFSHIYDDVEAELNEAAAQVRLASPLVSPLPSPLPSPLNSPQASPQVSPLVSPFGSPGCMAAYGDDPWYRYQQYHQQSLQYPFAQSLSPYQSPRTSITEETWLSPRPHSSSSRPSSRPTSPCGKRRHSSAEVIPG-LASPHLSPNATPSHSPRGSVTEESWMGGATFAPYHTLP--------VDVDVPSKTRRTYQANHNQDQASLFSGQEDSGLQDQGLANSGIAVSLPS-------LKKEDIVEHFLAVPTPFSWVKPKQAST-LYRSTSLPPLDCPLPSQYGQCELKMEIQPRAHHRAHYETEGSRGAIKSECGRHPVVKLIGYNEKPVSLQMFIGTADERYIRPHPFYQVHRITGKTVATPSQDTVISNTKVLEIPLLPENNMCASIDCAGILKLRNSDIELRKGETDIGRKNTRVRAVFRVNIPQHNGKLLSLQVASSPIECSQRLAQELPQVESFSPACGSASGGEEMRITGQNLNSESTVVFLEKGSDGKTQWEVNVRPLPEKSQNTSIVVKIPPYYKKTTASSTQVQFYVTNGKRKRSGSQFFTFLSAQVKQEFS----------------TQPAAPSGQTELLEQWLLSEET--LCASTHLSFSPQDASYLSRSHPADRSFN------SRTDLHSMFPSSLIEFNSSLYQKPHQDPSYKAQPSLPVAFPEQT-------------ATQLDKGYQCIRSQNLDNLILDASG---LHTMAAVSIPQSSSSQGLPTVSKVPSTSPSTSKNAEPASASLVESSEQYCVSENGDRLNIKEEPEEEKE---------LDFQSVGLQDITLDDGKTIDLITVKTLTLNTLDLTCTHR----HHTCTVHQESVDIRKFKTQFIYVEIQFLNKER-----SKSVNSAQCSGVTGRHEQKLCYFCCSPG----RYQWCSGLENP---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: . :****:*:***.. . . . . *: * .* * .: . . . *: * * ..: *** : *:*****:***..** *: .::: * . . ***:*:***:.***: ***.***.**:*****:********:*******::*******:. *.***.** ** *.* *::.*: *** :.:: ** :***:*:*:*.****** *. ******************* . *** ** .:*.*********::*: .... * *:.*:* ***:* .:***:::.*: : :*** ... .*: . ***:. ::**:**:**:* *** . * ::*::****** ***:::******:*:**::**************:*:. * ******:**.***:.*********:**:***.**************.**: :*:.**************.********************************* ****:*** .**:****:** *:***** *****::*.:* . *..**.** :**.*: .**.::*****.** .:**.: : : **.*. **:::***:: :.:::.**:**: *****:* ** **: .. :*** :*. **.:: .: :* :* * :::*.: : *.. . . . :*. * : .* ** : . *:. ..**: ... : :: * * : . :.. .::* *: :* .* * . : .*. ....* .. * *. *. . ... ::*.: *. : . ..: . * :: : .* : :. : :. * .* . *.*: ::: : .::. ..*. :.:. : * . * .. . ", "identical_positions": 407, "similar_positions": 287, "identity": "36.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-251", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80Y20-1", "uniprot_id": "ALKB8_MOUSE", "id": "Q80Y20-1", "name": "tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ALKBH8", "aln": "MNINHKGVLKLTKMEKKFLRKQSKARHVLLKHEGIQAVSYPTQSLVIANGGLGNGVSRKQLLLTLEKCGPVEALLMPPNKPYAFVIFQTIEESKKAYFTLNGKEIIDDLGQKIFLYLNFVEKAQWKNMGLEALPPGLLVVEEIISSEEEKKLLESVNWTEDTGNQNFQRSLKHRRVKHFGYEFHYESNTVDKDKPLPGGLPEVCSSILEKLLKEGYIKHKPDQLTINQYEPGHGIPAHIDTHSAFEDEIISLSLGSAIVMDFKHPEGVTVQVMLPRRSLLVMTGESRYLWTHGITPRKFDTVQASEQFKGGIITSDIGDLTLSKRGMRTSFTFRKVRRMPCNCSYSSVCDRQRKATPPSLTESSKEALELEQKHVHQVYNEIASHFSSTRHSPWPRIVEFLKALPSGSIVADIGCGNGKYLGINKDLYMIGCDRSQNLVDICRERQFQALVCDALAVPVRSGSCDACISIAVIHHFATAERRVEALQELARLLRPGGQALIYVWAMEQEYKNQKSKYLRGKRISQGDKDELNSATSTEEFLVNQTPEGVNEDPALSVNSSSITKEEEYKSRKVPNSELPIHINRTCFHSQDVLVPWHLKRNPGKDKAIEP---SGVAGCPDPSPVFHRYYHVFCDGELEASCQAVGDVSILQSYYDQGNWCVVLQKV-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96BT7-1", "uniprot_id": "ALKB8_HUMAN", "id": "Q96BT7-1", "name": "tRNA (carboxymethyluridine(34)-5-O)-methyltransferase ALKBH8", "aln": "MDSNHQSNYKLSKTEKKFLRKQIKAKHTLLRHEGIETVSYATQSLVVANGGLGNGVSRNQLLPVLEKCGLVDALLMPPNKPYSFARYRTTEESKRAYVTLNGKEVVDDLGQKITLYLNFVEKVQWKELRPQALPPGLMVVEEIISSEEEKMLLESVDWTEDTDNQNSQKSLKHRRVKHFGYEFHYENNNVDKDKPLSGGLPDICESFLEKWLRKGYIKHKPDQMTINQYEPGQGIPAHIDTHSAFEDEIVSLSLGSEIVMDFKHPDGIAVPVMLPRRSLLVMTGESRYLWTHGITCRKFDTVQASESLKSGIITSDVGDLTLSKRGLRTSFTFRKVRQTPCNCSYPLVCDSQRKETPPSFPESDKEASRLEQEYVHQVYEEIAGHFSSTRHTPWPHIVEFLKALPSGSIVADIGCGNGKYLGINKELYMIGCDRSQNLVDICRERQFQAFVCDALAVPVRSGSCDACISIAVIHHFATAERRVAALQEIVRLLRPGGKALIYVWAMEQEYNKQKSKYLRGNRNSQGKKEEMNSDTSVQRSLVEQMRDMGSRDSASSVPRINDSQEGGCNSRQVSNSKLPVHVNRTSFYSQDVLVPWHLKGNPDKGKPVEP---FGPIGSQDPSPVFHRYYHVFREGELEGACRTVSDVRILQSYYDQGNWCVILQKA-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QB52-1", "uniprot_id": "E9QB52_DANRE", "id": "E9QB52-1", "name": "tRNA (carboxymethyluridine(34)-5-O)-methyltransferase", "aln": "MESSRS--VRRTKEEKKLLRRQIKASHTLLKHEDITTVSHPTKHLVVSNGGLGNGVSRESLLEVLKEGGTVESLLTPPSKPYAFVSYSSIEAGQNAYTLLNGR-TLQCQDQTMTLYFSYVVKVDCDRSVSCALPPGLSVLEDFVSLEEELQILKAVDWTPHADDVTAQKALKHRRVKHYGYEFRYDNNNVDKDKPLPGGLPVECDALLQRCLAGGHISVLPDQLTVNQYQSGQGIPPHVDTHSPFEDTILSLSLGAKTVMDFKHPDGRSVAVVLPERSLLVMKGESRYLWTHGITPRKFDVVPVSETGGSGVMTSDLSNLTLSRRDTRTSLTFRKIRHTPCNCAYPSVCDSQRPPSPPVVPVAEGDACRLESQYVHQVYEEISSHFSSTRHSPWPKVRDFLLSLPPGSFLADVGCGNGKYLGINPAVRAVGCDRSVNLVQICIERGYDAFVSDALSVPLRRGSCDACISIAVIHHFATQERRRAAVRELIRLIKVGGRALIYVWAMEQEYNNQKSKYLK--EEASGSSREGGEELKTEENKAIQKEEHDRN----MISDIRCTDDGLSN---VTQPKIHVHTNRTAFLSQDLLVPWHLKGNMENKKGAASGCADIPVENAKQKPVFHRYYHVFQQGELEELCLGVKGVKVLRSYHDQGNWCVELEKTHGNFSIIAAGK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .:. : :* ***:**:* ** *.**:**.* :**:.*: **::**********:.** .*:: * *::** **.***:*. : : * .:.** ***: :: .*.: **:.:* *.: .. ****** *:*:::* *** :*::*:** .:.: . *::********:****:*:.*.*******.**** *.::*:: * *:*. ***:*:***:.*:***.*:****.*** *:*****: *******:* :* *:**.******.************ ****.* .** .*::***:.:****:*. ***:****:*: ****:*. *** ** :** .. :. :* .**.::*****:**:.*******:***:: :** :**.**::**:*********** : :***** ***:** ** ::*:*.***:**:* ***************** *** *::*: **:: **:************::******: . :.*.. * .. ..:. . * : . : :.: : *.:.:: :* ***.* ***:******* * : * . . .********** :**** * * .* :*:**:******* *:*. ", "identical_positions": 346, "similar_positions": 181, "identity": "51.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-256", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6X8Z5-1", "uniprot_id": "RHG31_MOUSE", "id": "A6X8Z5-1", "name": "Rho GTPase-activating protein 31", "aln": "MKNKGAKQKLKRKGAASAFGCDLTEYLESSGQDVPYVLKSCAEFIETHGIVDGIYRLSGITSNIQRLRQEFGSDQCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHRPEEGQLARIQNVILELPPPHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKKIEATICNGDAAFLAVRVQQVVIEFILNHADQIFNGGAPGALQQDESRTIT--KSLTLPALS--LPMKLVSLEEAQARSLATNHPARKER-RENSLPEIVPPP---FHTVLELPDNKRKLSSKSKKWKSIFNLGRSGSDSKSKLSRNGSVFVRGQRLSVEKATIRPAKSMDSLCSVPVEGKENKGNFSRTVTTGGFFIPATKMHASSTGSSCDLSK-EGEWGQEGMPA----------GAEGGCEVG--------GQIRPLPEQLKVFRPIGDPESEQSAPKLLGMFYT--SSDSPGKSVFTSSLFQMEPSPRHQRKALNISEPFAVSVPLRVSAVISTNSTPCRTPPKELQS-LSSLEEFSFQGSESGGWPEEEK------PLGAESFPGSVTKKAATEDTKPEPE-VPGRAECSQSPPLDPGTQV-EKKTLHVSLGSQVSKEAEKRPKAEK-----VMEESQGASQPKPSTPQESLGAGTEPLILHEMDEEDLAQALIWPEIQQELKIIESEEEFSSLPPAAQKTSPIP---ESSPAPFPFPEAPGSLPS------SSAPREVWTRDAANQSIQEAAILTDREKLEPVCSLLESESQQELSPDPASLAPLEMLLFEKVSSPARIEIGGPRNLSPPLTPAPPPPTP-LEEEPEVLLS-KEGPDREDAARDSRTDVYTEQPTPKESPGIPTPCQREEAIASPNEKQNARHAVPENKGPGLPSPTKEVDIIPQEEGGAPHSAQEPSDCDEDDTVTDPAQHGLEMVEPWE----EPQWVTSPLHSPTLKEVQESQTQGSQGHRLERRLCHRPSLRQS-HSLDSKTTGNSHWTLEAPFSSSCANLETERNYEPLQPPAARTKIAGLEEKALKAFREFSGLKGLEVLPSQKGPSGIQPKPVETNFMGLAEGKEQEPQLELSNRQMKHSDVPGPDSSKESSPRAQDSTLPGEHPLQLQLKNTECGPSKGKHRPSSLNLDSATPIADLFRLENGAPFSSPGIELSELGDTKVTWMSSSHCKAAPWN--SQDTQDLDIVAHTLTGRRNSAPVSVSAVRTSFMVKMCQAKAVPVIPPKIQYTQIPQPLPSQSTGEGGAQPLERSQEEPGSTPEIPQKSTKDDSPSSLGSPEEEQPKQETGASASRRQASITSCMYEGSSCSPEPSASTLASTQDAVVQCRKRTSETEPSGDNLLSSKLERASGGPKAFHRSRPGRPQSLILF----PIMDHLPSSPTVIDSKVLLSPIRSPTQTVSPGLLCGELAENTWITPEGVTLRNKMTIPKNGQRLETSTSCFYQPQRRSVILDGRSGRQIE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2M1Z3-1", "uniprot_id": "RHG31_HUMAN", "id": "Q2M1Z3-1", "name": "Rho GTPase-activating protein 31", "aln": "MKNKGAKQKLKRKGAASAFGCDLTEYLESSGQDVPYVLKSCAEFIETHGIVDGIYRLSGVTSNIQRLRQEFGSDQCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPEEGQLARIQNVIQELPPSHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKEIEATGCNGDAAFLAVRVQQVVIEFILNHVDQIFNNGAPGSLENDENRPIM--KSLTLPALS--LPMKLVSLEEAQARSLATNHPARKER-RENSLPEIVPPMGTLFHTVLELPDNKRKLSSKSKKWKSIFNLGRSGSDSKSKLSRNGSVFVRGQRLSVEKATIRPAKSMDSLCSVPVEGKETKGNFNRTVTTGGFFIPATKMHSTGTGSSCDLTKQEGEWGQEGMPP----------GAEGGFDVSSDRSHLQGAQARPPPEQLKVFRPVEDPESEQTAPKMLGMFYT--SNDSPSKSVFTSSLFQMEPSPRNQRKALNISEPFAVSVPLRVSAVISTNSTPCRTPPKELQS-LSSLEEFSFHGSESGGWPEEEK------PLGAETSAASVPKKAGLEDAKAVPE-APGTVECSKGLSQEPGAHLEEKKTPESSLSSQHLNELEKRPNPEK-----VVEEGREAGEMESSTLQESPRARAEAVLLHEMDEDDLANALIWPEIQQELKIIESEEELSSLPPPALKTSPIQPILESSLGPFIPSEPPGSLPCGSFPAPVSTPLEVWTRDPANQSTQGASTAASREKPEP---------EQGLHPDLASLAPLEIVPFEKASPQATVEVGGPGNLSPPLPPAPPPPTP-LEESTPVLLS-KGGPEREDSSRKLRTDLYIDQLKSQDSPEISSLCQGEEATPRHSDKQNSKNAASEGKGCGFPSPTREVEIVSQEEEDVTHSVQEPSDCDEDDTVTDIAQHGLEMVEPWE----EPQWVTSPLHSPTLKDAHKAQVQGLQGHQLEKRLSHRPSLRQS-HSLDSKPTVKSQWTLEVPSSSSCANLETERNSDPLQPQAPRREITGWDEKALRSFREFSGLKGAEAPPNQKGPSGVQPNPAETSPISLAEGKELGTHLGHSSPQIRQGGVPGPESSKESSPSVQDSTSPGEHPAKLQLKSTECGPPKGKNRPSSLNLDPAIPIADLFWFENVASFSSPGMQVSEPGDPKVTWMTSSYCKADPWRVYSQDPQDLDIVAHALTGRRNSAPVSVSAVRTSFMVKMCQARAVPVIPPKIQYTQIPQPLPSQSSGENGVQPLERSQEGPSSTSGTTQKPAKDDSPSSLESSKEEKPKQDPGAIKSSPVDATAPCMCEGPTLSPEPGSSNLLSTQDAVVQCRKRMSETEPSGDNLLSSKLERPSGGSKPFHRSRPGRPQSLILFSPPFPIMDHLPPSSTVTDSKVLLSPIRSPTQTVSPGLLCGELAENTWVTPEGVTLRNKMTIPKNGQRLETSTSCFYQPQRRSVILDGRSGRQIE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QGF9-1", "uniprot_id": "E9QGF9_DANRE", "id": "E9QGF9-1", "name": "", "aln": "MKNKAAKLKSKRKGTDNAFGCDLSEHLQSSGQDVPHVLKTCAEFIEKHGIVDGIYRLSGITSNIQKLRQEFSSELCPDLTKEVYLQDIHCVGSLCKLYFRELPNPLLTYELYSKFTHAVSVKEEQEQLRNIRSAIKELPESHFRTLEYLTKHLAYLATLSHQTNMHARNLALVWAPNLLRSKEVEVPSCNGDIAFLEVRVQQSVVEFILNHTEQIFNLEFQPSKARDGPSMACGEKYATLPASTQCGPMKLMSLEEAQARSLSPNHPVMKERQRENSLPDTSTAA--MYHTVIDLSDSRRKFSGKSKKWKSIFSLGRSVIDSKGKLSRNGSVFMRAQ-NSSEKTAIRPSKSMDSLCSFQAPDEDK----AAAEGANGMFIPIHKSRTLGS-DINYLNKKDPKWDLESQTASGGSLNEKREGASNASSSSSSPSSSLSPLQKSLPEQLKVFKGDERGGCQPTSPKNRRMLYSGSANNGSSRPSFPGSLFPLESSPRHQRKALNISEPFAVSVPLRVSAVINSNSTPCRAPGKERDRGLGGLFRPSKEAGPLEGHRRESMGAAGLCGAGNFSFTDWETGLAGRAIGSGHRENSSGGSGCSIYSNSSSFPMENEEQSGEGDFTDAIAMATTKSKDAEVRELIATVENFQPQASSETKAIGEELETTSTKQEMAKLDKLELIDKVPSSGMHDKVSITEVKT--TNMPNDGVKPCITKINGNQGNLKLSAQARRSSLPSN---TVSSKGLFIDLTKNVMFDHPGATTFNSVMKHMP-------ERLLSCDGDWNYLDSDSDRTEHKARNIITTSLQLSPFLHLKETDILQDAEPCIEEEPKIDLCEKDGTSKSDSKDNTSVSVKLDLHTDEESLRTSDICEKE--NKKVSDEPRKLDLAGRIKG------NLERLSTCLNEKHLTLEIQDDVDACGSN---------LDQVEPWEDLCSAQQWVTSPLHSPKLEDLFPTQREILPCQKVHCQVLDKPNADELPNSRNPEAKEPAALDEIAPTQTEAAVTAELGNSD--FPTGKKN-----ADTDVACFAQITAHFDRDKFKFEGAKDDIKLEIPQVKQLKTFNDPEETTGMQN--------------MSKAKQKRSQRFHRQTSHEFCIMEKSQGSG--KPKLRPCSLNLDLGH-----------QGFR--DISNSQYLKSGKQWMTP---EAKDGS--SSLELELFLSGPKAPMRRNSAPVSVSSVRTAFMIKTCQAKAVPVIPPKIQYSHIPHTLPERKNAEKSTDQVNKSTPEKKPT---KSKLGKASSLFPLQKVCREDRQSTEPPSGIQRHKSMNSATCN--------ENYKPTSIPDLPVLRRKRSANGDTFMD---RPRPERSSLLQRSSFRNRP-RPQSLILFSPPFPIMDYP---SVGDDNKQALSPIKAETSPFDA--YANELAEN-LKTTEGVTLRNKMTLPKSGQRLETSTSCFYQPQRRSMIFDNRSNRQIE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****.** * ****: .******:*:*:*******:***:******.************:*****:*****.*: *****:*******************************.***.*** *: ** .*:..* *** .*:****** :***::*::* :********************::*.. **** *** ***** *:******.:**** : .* * **** : ****:**********:.***. *** ******: .. :***::*.*.:**:*.*********.**** ***.*********:*.* * **::***:********. . .::. : :.*:*** * :: .: . *.* : :*. *. .. **... . . :. *******: .: ::** *:*: :.:...:. *..*** :*.***:***********************.:******:* ** : *..* . * ... * .*. * : . . *. . * .* ** .. . *::: . .: . * ..* .:*: : .. :..: *. : : : ::*: :* : : . :::::.* * : :.:* . *.. :.. : .***. * : . . . *: . * * * * . . .*. .: . * . . * :**.. : *. * *..:.*: . ..: : . ::* . *: * .:: . . . . ** . * :* . . *: *. .: *: ***** **********.*:: :* : :::. :: .:*. : :* :.:.. : .* .:..* * : * . : :. : .* :::. . : : . ..:: : :.. : :. * . : ** .. * .* : *. .* * * **.***** . * .:. *: .. **:. :* *. :* : . . **********:***:**:* ***:***********::**:.**.:...* ..: :::* .* .* * .* .* . .*. :. . : .. : . * * * *** :: :. * .: **.* :. .*.** ******** ****: .. *.* ****:: *..... ..***** *.**********:**.******************:*:*.**.****", "identical_positions": 522, "similar_positions": 373, "identity": "35.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-257", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C5X8-1", "uniprot_id": "TTYH1_RAT", "id": "P0C5X8-1", "name": "Protein tweety homolog 1", "aln": "----MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSGFAPRDQEYQQ----------------ALLLVAALAGLGLGLSLIFIAVYLIRFCCCR------PPEPPGAKSPPPGGG-----------CVTWSCIAALLVGCAGIGIGFYGNSETSDGVSQLSSALQHANHTLSTIDDLVLETVERLGEAVRTELTTLEEVLSERVELVAATRGARRQAEAAAQHLQGLAFWQG----------------------------------------VSLSPVQVAEDVTFVEEYRWLAYVLLLLLVLLVCLFTLLGLAKQSKWLVVVMTAMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDTYVLNLTQEETGISSDILNYYFLCNQAVSNPFQQRLTLSQRALASIHSQLQGLEREASPQFP--AAQKPLLSLEETLNVTERSFHQLVALLHCRSLHKDYGSALRGLCEDALEGLLFLMLFSLLSAGALATTLCSLPRAWALFPP-SDDYDDTDDD--DPFNPQESKR-------------FVQWQSSI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D3A9-1", "uniprot_id": "TTYH1_MOUSE", "id": "Q9D3A9-1", "name": "Protein tweety homolog 1", "aln": "----MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSGFAPRDQEYQQ----------------ALLLVAALAGLGLGLSLIFIAVYLIRFCCCR------PPEPHGAKSPPPGGG-----------CVTWSCIAALLVGCAGIGIGFYGNSETSDGVSQLSSALLHANHTLSTIDDVVLETVERLGEAVKTELTTLEEVLSVRMELVAATRGARRQAEAAAQYLQGLAFWQG----------------------------------------VSLSPVQVAEDVTFVEEYRWLAYVLLLLLVLLVCLFTLLGLAKQSKWLVVVMTAMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDTYVLNLTQEETGLSSDILSYYFLCNQAVSNPFQQRLTLSQRALASIHSQLQGLEREAIPQFS--AAQKPLLSLEETLNVTERSFHQLVALLHCRSLHKDYGSALRGLCEDALEGLLFLMLFSLLSAGALATTLCSLPRAWALFPP-SDDYDDTDDD--DPFNPQESKR-------------FVQWQSSI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H313-1", "uniprot_id": "TTYH1_HUMAN", "id": "Q9H313-1", "name": "Protein tweety homolog 1", "aln": "----MGAPPGYRPSAWVHLLHQLPRADFQLRPVPSVFAPQEQEYQQ----------------ALLLVAALAGLGLGLSLIFIAVYLIRFCCCR------PPEPPGSKIPSPGGG-----------CVTWSCIVALLAGCTGIGIGFYGNSETSDGVSQLSSALLHANHTLSTIDHLVLETVERLGEAVRTELTTLEEVLEPRTELVAAARGARRQAEAAAQQLQGLAFWQG----------------------------------------VPLSPLQVAENVSFVEEYRWLAYVLLLLLELLVCLFTLLGLAKQSKWLVIVMTVMSLLVLVLSWGSMGLEAATAVGLSDFCSNPDPYVLNLTQEETGLSSDILSYYLLCNRAVSNPFQQRLTLSQRALANIHSQLLGLEREAVPQFP--SAQKPLLSLEETLNVTEGNFHQLVALLHCRSLHKDYGAALRGLCEDALEGLLFLLLFSLLSAGALATALCSLPRAWALFPP-SDDYDDTDDD--DPFNPQESKR-------------FVQWQSSI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AHW7-1", "uniprot_id": "A0A8M3AHW7_DANRE", "id": "A0A8M3AHW7-1", "name": "Protein tweety homolog", "aln": "-MAAIATVPNYTPSVWVRLCHAIPRLSLTMQMRDSVFTPDSWEYQQ----------------TLLVLSSFSAIALVLSLLVILCFLIHYCCCHRGESGRDAEEEEEDDDASGGHGYSGKKGRGICCVTWVSVAAVTLCCVAIGVGFYGNSEANDGMYQLTSSLLTANYTLASIDLLVSDTISGLQRSVSGPLTSMEDVFGGHKPALVPTRSCRRLSERVVSLLSNLTLGRGLIPIADGFYRTNGSESIVGALTPAPPSVAPTLSPSANSIPAPFSPGWAANTLMVNEDYRWLSYVLLLLVDLVVCFFILLGLAKQSRWLLILMTVLAWLSLFMSWGSLGLETPTVVALSDFCFDPNTFVLNSTHFNSGTSPEVLDYYLTCSRKMSSPFQQILTQSQRALSSIHSHLSSLERDALPRFP--KAERSLREVQQILNTTEGNFHQLVALLNCRGLNKDYVDSLKGLCYDGMEGLLYLSLYSFLSALAFTAILCSLPGAWRSFHSDSDDYEDSDSESEDPFTSHQARRQTATGSQRGALPPFYSYQGAAWTPPFSSAPP----------------------------LPTPNVSSNGNPGYENLPLSDRQSPPPSYSPSMLTGYGGSQSHSNPSHSRNLYSH------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U6L4-1", "uniprot_id": "TTY1_DROME", "id": "Q9U6L4-1", "name": "Protein tweety", "aln": "MGDYHEFTDQYKVPVIAKLLHALPHYNITFHKINSTFRPNDEIYLE----------------SLGILGSVPAALLIVSLLGLLFYLMTRCCDR------KPRPAHSITS-----------------LKVALSIVTVMCCAAIGLGLYGNDDLHNGLLEVLTAGRKVDNLVTTIRNQTHILENTLTNRIRPQLVELADIFDQPVSNQTALSKLFVSLNIVQGNVTLATNAASDIR----------------------------------RPLMGISMTHFLTRGDQWELIRWPGTVATLALLLVLCAVLLVGVARHSRCALILFSVCGLLAVTGSWLMSGLYLSSSVAVGDLCISPADFLVSTAPRD--LPTNVLLHYTQCEPGHTNPFTQRLRESQNSLNNARSAMATVMKISLVLFKSSGLQPKLGAVNADLNSSERLLTQLTALVDCKAVHHNFLAAARGLCEGGLLGLVLMLIASFIAAILLTIMVWVDSHTWIYIRK-RNDYAQVDEPSYISHPAPQNHQQMMNAARTLPRNHNGHFSPPVISGSHTLQHPSKRQQHEMMAHAHIQQNMRAMGTHTLGRLPSHNHSPTHMTGPNNAAAVAAAANAAANMPPTTQAAQQQQQQQAQQQQQQAQQQLGGPQPIYCHHPHQHPHPHPHQHPHSHSAAAVAAAVQHQHAIYHQQQAQQYGTYTTAAHHAPHHLGPGQSQIYQQIPAHLAPQLAANGNPHSIYQPLVAVSQGSIYVSNMATMRRQNSQGGPQIPAHQHPPSLHQQQQQPPPPSQQQQQLHQLKSPQQHQQQLQQHQQQQQQQHHQQQHHQQQHQQQQQQHHQQQQPNESDVVPISTAMDTAIYDRDKQIYKCSTLRQGGKFDPKYKPSILNCPLPEIPKDAEQPKVESIYEQRQQAHHQNYSKTLQRPPMMLPPQMKAIPPPRIGTPTSPPPPVAQPLNESNGGVPSGLQNGGAVVGGGGANANEDTSLPPPPLEAQTEATKARMGAGPAANGKVLHNGGGGGSVGGGGGGAVDDDDDLPPPPPAITDESNYAVTEL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W5A5-1", "uniprot_id": "TTYH2_DROME", "id": "Q9W5A5-1", "name": "Protein movement modulator", "aln": "---------MEQPSILVKILHSIPHVNYTFRRVNDTFNPDSDVYLEPTNNKLQCQQKGIELQSLVILASIPAGLLIGSLLGLLLYLLTRCCDR------RQRKPSAQR-----------------CQSCSLVIITLMTCAAIGLGLYGNDDFHNGLLQAFGSGKSVEGLVLTLKRQTESIKHDLETRMAG--HKVEQLVEKPHYNQTVVMLLIETSRLVTENTSRAVASLDSMVHYFMKAK---------------------------GSENDTSLMGLLQLGEFYESIRWPATLAFLTVLLLLCTVLVIGVARRSRCTLIFFSVSGLFCIIICWLLAGVYLASSVAAGDFCMRPHDYMCRQVGMR-----SPYVDFLNCGTPR-NRFILRLNESRDLVDRARESVEHMQRMSQETYPHIDIQRTLNAMDNDLEITLRNLTTLSATLDRRTIDMHYEEALRGLCGGGLLGLSLMMVAGLLTSFLLTILVYADSHAWIYLTK-RPTLDADKSETAPLFPASNAPS--------------ASISPTAPLSTGTINRTLLHHQQASSGGGSGTLPGSGGGAGAGGGVGANGHNGVGPYRNGSAGLRQGLASPSSQSSHTSSTATYNNGTTSYHNSHQQHNN----HLYSNHYSHSNNHYNNTQHRTNPAAGAVAAAVGVVSSGQRSPSPPPVYDLVHGTRSGHHTLGRLPSHHQQSATYLPGPN---NGKYATLSKQCKTLESNDFY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:: * :*: . :: . * * . * : :* ::.:... * **: : :*: ** : . . *..**:*:***.: :*: : : .: : :: . * : : ::. . . . . . * * ** . : * : *::* . ::*:*::*: ::.::. . : : .* *: .: *. .*:* * :: . . : * . * * *: : :. : : : : : : * :: *: : : * * :. : :. .: : :*** ..: ** : : .:::: :: : . :* : .. . . : . . ", "identical_positions": 51, "similar_positions": 134, "identity": "4.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-259", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZN55-1", "uniprot_id": "ZN574_HUMAN", "id": "Q6ZN55-1", "name": "Zinc finger protein 574", "aln": "MTEESEETVLYIEHRYVCSECNQLYGSLEEVLMHQNSHVPQQHFELVGVADPGVTVATDTASGTGLYQTLVQESQYQCLECGQLLMSPSQLLEHQELHLKMMAPQEAVPAEPSPKAPPLSSSTIHYECVDCKALFASQELWLNHRQTHLRATPTKAPAPVVLGSPVVLGPPVGQARVAVEHSYRKAEEGGEGATVPSAAATTTEVVTEVELLLYKCSECSQLFQLPADFLEHQATHFPAPVPESQEPALQQEVQASSPAEVPVSQPDPLPASDHSYELR----NGEAIGRDRRGRRARRNNSGEAGGAATQELFCSACDQLFLSPHQLQQHLRSHREGVFKCPLCSRVFPSPSSLDQHLGDHSSESHFLCVDCGLAFGTEALLLAHRRAHTPNPLHSCP-CGKTFVNLTKFLYHRRTHGVGGVPLPTTPVPPEEPVIGFPEPAPAETGEPEAPEPPVSEETSAGPAAPGTYRCLLCSREFGKALQLTRHQRFVHRLERRHKCS-ICGKMFKKKSHVRNHLRTHTGERP---------------FPCPDCSKPFNSPANLARHRLTHTGERPYRCGDCGKAFTQSSTLRQHRLVHAQHFPYRCQECGVRFHRPYRLLMHRYHHTGEYPYKCRECPRSFLLRRLLEVHQLVVHAGRQPHRCPSCGAAFPSSLRLREHRC--------------AAAAAQAPRRFECGTCGKKVGSAARLQAHEAAHAAAGPGEVLAK------------------------------------------------------------------EPPAPRAPRATRAPVA-SPAALGSTATASPAAPARRRGLECSECKKLFSTETSLQVHRRIHTGERPYPCPDCGKAFRQSTHLKDHRRLHTGERPFACEVCGKAFAISMRLAEHRRIHTGERPYSCPDCGKSYRSFSNLWKHRKTHQQQHQAAVRQQLAEAEAAVGLAVMETAVEALPLVEAIEIYPLAEAEGVQISG----------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BY46-1", "uniprot_id": "ZN574_MOUSE", "id": "Q8BY46-1", "name": "Zinc finger protein 574", "aln": "MTEESEETVLYIEHRYVCSECNQLYGSLEEVLVHQNSHVPQQHFELVGVADPGVTVATEAASGTGLYQTLIQESQYQCLECGQLLLSPSQLLEHQELHLKMMAPQEAVPAKPPPKVPPLGSSAIHYECVDCKALFASQEMWLSHRQTHLRATPNKAPAPVVLGSPVVLGPPVGQARVAVEHSYRKAEEGGEGAAVPSVAATT-EMVTEVELLLYKCSECSQLFQMPADFLEHQATHFPAPVPEAAEPATQQETQVPSPTEAAVSQPEPLPASDHSYELRNELRNGEAIGRDRRGRKPRRNNSGESGGAATQELFCSACDQLFLSPHQLQQHLRSHREGVFKCPLCSRVFPSPSSLDQHLGDHSSESHFLCVDCGLAFGTEALLLAHRRAHTPNPLHSCP-CGKTFVNLTKFLYHRRTHGAGGVPLPTTPVPPEEPAISFPEPAPAETGELEAPELPVCEESSAEPAAPGSYRCLLCSREFGKALQLTRHQRFVHRLERRHKCS-ICGKMFKKKSHVRNHLRTHTGERP---------------FPCPDCSKPFNSPANLARHRLTHTGERPYRCGDCGKAFTQSSTLRQHRLVHAQHFPYRCQECGVRFHRPYRLLMHRYHHTGEYPYKCRECPRSFLLRRLLEVHQLVIHAGRQPYRCSSCGAAFPSSLRLREHRC--------------AAAAAQAPRRFECGTCGKKVGSAARLQAHEAAHAAAGPGEVLAK------------------------------------------------------------------EPPAPRASRATRTPVAPSPTALSGTTSAAPAAPARRRGPECSECKKLFSTETSLQVHRRIHTGERPYPCPDCGKAFRQSTHLKDHRRLHTGERPFACEVCGKAFAISMRLAEHRRIHTGERPYSCPDCGKSYRSFSNLWKHRKTHQQQHQAAVRQQLAEAEAAVGLAVMETAVEALPLVEAIEIYPLAEADGVQISG----------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5MYW4-1", "uniprot_id": "ZN667_RAT", "id": "Q5MYW4-1", "name": "Zinc finger protein 667", "aln": "---------------------------------------------------------------------------------------------------------------MPAARGKS--------KSKAPVTFGDLAIYFSQEEWEWLSPNQKDLYEDVMLENYHNLVSVG-LACRRPNIIALLEKG-----------------------------------------KAPWMVEPSRKRRGPELGSKDETKKLPPSQCNKSGP-----------------------------------SICKKPDSSQQKVPTEKAKHNKNAVPRKNKKGHSGKKSLKCNSCGKTFFRSLSLKLHQGFHTGERSYECSTCGQVFRQILSLILHQRVHTQNKSYECDKCGDIFNKKLTLMIHRRSH----------------------NGKENFHHEKTSDSCPSLSPHHNNHAIDSIHQCRKCGKVFSRMSSLLLHKKIHN-RKRIQKYS-ACGRGFKKK-PVLVHKRICIGKK----------------------THEN-KALIQSLRQRTYQSENPFTCRKCRKSFSRISALMLHQRAHTSGNPYKCDKCQKDFGRLSTLILHLRIHSGEKQFKCNKCEKVCNRLSSFIQHKKIHKRKKKLIECKECGKMFGGMKNLKVH-----------------LNIHSEEKPFKCNKCSKVFGRQSFLSEHQRIHTGEKP--------------------------------------------------------------------------------------------------------------YQCEECGKAFSHRISLTRHKRIHSEDRPYECDLCGKAFSQSAHLAQHERIHTGEKPYACKICKKSFTQRISLILHERSHTGEKPYECNECGKAFSSGSDLIRHQRSHSSEKPYECSKCGKAYSRSSSLIRHQSIHSEEMS-----------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q2TL60-1", "uniprot_id": "ZN667_MOUSE", "id": "Q2TL60-1", "name": "Zinc finger protein 667", "aln": "---------------------------------------------------------------------------------------------------------------MPAVRGKS--------KSKAPVTFGDLAIYFSQEEWEWLSPMQKDLYEDVMLENYHNLVSVG-LACRRPNIIALLEKG-----------------------------------------KAPWVIEPSRRRWGPESGSKYETKKLPPNSCHKSGP-----------------------------------SICEKPTSSQQKVPTEKAKHNKSSVPSKSKKEHSGKKSLKCNLCGKTFFRSLSLKLHQDFHTGERSYECSTCRHVFRQILSLILHQRVHNWNKSYECDKCGDIFNKKLTLMIHRRIH----------------------NGKESFHHEKASDSCPSLSLHRNNHTTDSVHQCRKCGKVFSRMSSLLLHKRSHN-RKKIQKYN-KYKRGFKKQ-PVLVHKRVCIGKK----------------------THESKKALIQSARQKTCQSENPFMCGKCGKSFSRISALMLHQRIHTSGNPYKCDKCQKDFGRLSTLILHLRIHSGEKQFKCSKCEKVCSRLSSFIQHQKIHKRKKKLIACKECGKMFGGMKNLKVH-----------------LNIHSEEKPFKCNKCSKVFGRQSFLSEHQRIHTGEKP--------------------------------------------------------------------------------------------------------------YQCEECGKAFSHRISLTRHKRIHSEDRPYECDLCGKAFSQSAHLAQHERIHTGEKPYACKICKKSFAQRISLILHERSHTGERPYECNECGKAFSSGSDLIRHQRSHSSEKPYECSKCGKAYSRSSSLIRHQSIHSEETP-----------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5HYK9-1", "uniprot_id": "ZN667_HUMAN", "id": "Q5HYK9-1", "name": "Zinc finger protein 667", "aln": "---------------------------------------------------------------------------------------------------------------MPSARGKS--------KSKAPITFGDLAIYFSQEEWEWLSPIQKDLYEDVMLENYRNLVSLG-LSFRRPNVITLLEKG-----------------------------------------KAPWMVEPVRRRRAPDSGSKCETKKLPPNQCNKSGQ-----------------------------------SICQKLVSAQQKAPTRKSGCNKNSVLVKPKKGHSGKKPLKCNDCGKTFSRSFSLKLHQNIHTGEKPFECSNCRKAFRQISSILLHQRIHSGKKSHECNKCGESFNQRTTLILHMRIH----------------------DGKEILDCGKALSQCQSFNIHQKIHVVGNVCQCRKCGKAFNQMSSLLLHKKIHN-GKKTHKYN-KCGRGFKKKSVFVVHKRIHAGEK----------------------IPENAKALSQSLQQRSHHLENPFKCRKCGKLFNRISPLMLHQRIHTSEKPYKCDKCDKFFRRLSTLILHLRIHNGEKLYRCNKCEKVCNRHSSLIQHQKVHTKKKKLFECKECGKMFSGTANLKIH-----------------QNIHSEEKPFKCNKCSKVFGRQSFLIEHQRIHTGEKP--------------------------------------------------------------------------------------------------------------YQCEECGKAFSHRISLTRHKRIHTEDRPYECDQCGKAFSQSAHLAQHERIHTGEKPYTCKTCGKAFSQRTSLILHERSHTGEKPYECNECGKAFSSGSDLIRHQRSHSSEKPYECSKCGKAYSRSSSLIRHQNTHSEEKA-----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8TAW3-1", "uniprot_id": "ZN671_HUMAN", "id": "Q8TAW3-1", "name": "Zinc finger protein 671", "aln": "------------------------------------------------------------------------------------MLSPVSRDASDALQGRKCLRPRSRRLPLPAAVRAHGPMAELTDSARGCVVFEDVFVYFSREEWELLDDAQRLLYHDVMLENFALLASLG-IAFSRSRAVMKLERG-----------------------------------------EEPWVYDQVDMTSATEREAQ---RGLRPGCWHG---------------------------------------VEDEEVSSEQ----------------------------SIFVAGVSEVRTLMAELES--------HPCDICGPILKDTLHLAKYHGGKARQKPYLCGACGKQFWFSTDFDQHQNQP----------------------NGGKLFPRKEGRDSVKSCRVHVPEKTLT----CGKGRRDFSATSGLLQHQASLS-SMKPHKST-KLVSGFLMG-------------------------------------------------QRYHR------CGECGKAFTRKDTLARHQRIHTGERPYECNECGKFFSQSYDLFKHQTVHTGERPYECSECGKFFRQISGLIEHRRVHTG----------------------------------------------ERLYQCGKCGKFFSSKSNLIRHQEVHTGARP--------------------------------------------------------------------------------------------------------------YVCSECGKEFSRKHTLVLHQRTHTGERPYECSECGKAFSQSSHLNVHWRIHSSD--YECSRCGKAFSCISKLIQHQKVHSGEKPYECSKCGKAFTQRPNLIRHWKVHTGERPYVCSECGREFIRKQTLVLHQRVHAGEKL-----------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6ZS27-1", "uniprot_id": "ZN662_HUMAN", "id": "Q6ZS27-1", "name": "Zinc finger protein 662", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MLENYGAVASLAAFPFPKPALISQLERG-----------------------------------------ETPWCSVPRGALDGEAPRGISSGYPFLKP-------------------------------------------------------------------------------------AGISHPEQVEEPLNLKLQGEGPSLICPEG-VLKRKKEDFILKEEIIEEAQDLMVLSSGPQWCGSQELWFGKTCE----------------------EKSRLGRWPGYLN-------------------GGRMESSTNDIIEVIVKDEMIS-VEESSGNT-DVNNLLGIH-------------------------------------------------HKILNEQIFYICEECGKCFDQNEDFDQHQKTHNGEKVYGCKECGKAFSFRSHCIAHQRIHSGVKPYECQECAKAFVWKSNLIRHQRIHTG----------------------------------------------EKPFECKECGKGFSQNTSLTQHQRIHTGEKP--------------------------------------------------------------------------------------------------------------YTCKECGKSFTRNPALLRHQRMHTGEKPYECKDCGKGFMWNSDLSQHQRVHTGDKPHECTDCGKSFFCKAHLIRHQRIHTGERPYKCNDCGKAFSQNSVLIKHQRRHARDKPYNCQIS--------HLLEH--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P821-1", "uniprot_id": "ZN574_DANRE", "id": "A0A8M9P821-1", "name": "Zinc finger protein 574", "aln": "---------MESSSVYMCFPCYREFPTLEEVLAHQMTCTAENPQLLPNETPVEAAAAAAGLPQVAMQAVTVPQIQTQTAVDLSSLLQQKKTIQADAPRVLYQCADCEVLFDALSLWQQHRKMGCCLETEPAGEQTEETYEAVAQPQPSQKENENAVQEQNTPEQTQVKEVVEIRFESVSQGSVEVAGKVAAPATSEE---------------------------------EESSNSVSKEASATHEASSVETSAEASSPATRRRGQKKAKPPSSLLCVECGQSFSLVPELVTHRRTQHGLKDAIHRCAVCGEGFLNTTLFLYHRRQHRSEVEEEPKQASSGIPQISTAMLEAPGEGLLLLATAGEGQSLMEVTTLEQTITETPVAQVEVELEGNEIRGTEQEPMVEGAEILVEKTEEMLEEHEAPDQE--VKMELVIEKVEGNVQMEKIGADEEIQDAVESNASENTSTAFLCHQCGSVFSNDQELAKHRKAEHGLEAALHTCGDCGAKFMSTTQFLYHRRQHKNTTAGHLVTAEVKSRLYTTAASGAAAADGGLEAPAKLSREWSRTALPHECPHCGQGFTRRSRLREHVFQHTGEKLFNCKICKKSFPSPANLLRHSLIHGGSRIYSCPICDKRFFQPTSLKRHMMTHQEGVQERRTRGRGKGRGPSSDGRLHICPECPASFKLEAQLKSHRLLHTSHPFPCSVCGEAFIRRKELDLHSLIHQDKEPKMCPNCGSQFLNQTVLDTHLQRCTGEQTGQRKYKGQGRGKVGGQLECDMCGHRCVTQDGLDLHRLSHTGQTPLRCPLAPCRRRFASSAALGEHLVAHCCGALGKRNAPRRFTCEFCGKEFAYASTFTVHMRTHTNERPFECAQCGKRFRQLPHLQDHERIHSGERPFTCWVCGKSFSVAARLTEHARVHSGERPYVCPRCPTAFRSRPNLDKHMRIHANDPVDPTAQNVMDDDAAVQTILLVQESASSSPSSSSSVMPVVQEGMFVTEEGGSSVVFLHPNMSMPTITVPAISVPSMNMPNISVVAGQDVPHTIEVILEETV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . : : . : : : : * .* : * : . : * * : *. * * : * * * : * * : : * : : * *.: . * *. * * *. * * *: :: * * *: ::*: * *** * ..* * *:*:.: . * * *:* * * : *:**:** * * .:: . . * :* : * : ", "identical_positions": 53, "similar_positions": 55, "identity": "5.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-260", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q504L7-1", "uniprot_id": "ZN574_RAT", "id": "Q504L7-1", "name": "Zinc finger protein 574", "aln": "MTEESEETVLYIEHRYVCSECNQLYGSLEEVLVHQNSHVPQQHFELVGVADPGVTVATEATSGTGLYQTLIQESQYQCLECGQLLLSPSQLLEHQELHLKMMAPQEAVPAEPPPKVPPLSSS--TIHYECVDCKALFASQEMWLSHRQTHLRATPN-----------------------KAPAPVVLGSPVVLGPPVGQARVAVEHSYRKAEEGGEGAAVP----------------------------SVAAAT-EMVTEVELLLYKCSECSQLFQMPADFLEHQATHFP--------------APVPEAEEPATQQET------LVPSPTEAAVSQPDPLPASDHSYELRNELRNGEAMGRDRRGRKPRRSSSG---ESG--ATQELFCSACDQIFLSPHQLQQHLRSHREGVFKCPLCSRVFPSPSSLDQHLGDHSSESHFLCVDCGLAFGTEALLLAHRRAHTPNPLHSCP-CGKTFVNLTKFLYHRRTHGAGGVPLPTTPVPPEE------------------------------------PAISFPEPAPAETGELEAPELPVSEES---------------------------------SAEPAAPGTYRCLLCSREFSKALQLTRHQRFVH-RLERRHKCSICGKMFKKKSHVRNHLRTHTGERPFPCPDCSKPFNSPANLARHRLTHTGERPYRCGDCGKAFTQSSTLRQHRL-VHAQHFPYRCQECGVRFHRPYRLLMHRYHHTG--EYPYKCRECPRSFLLRRLLEVHQLVVHAG-RQPHRCPSCGAAFPSSLRLREHRCAAAAAQAPRRFECGTCGKKVGSAARLQAHEAAHAAAGPGEVLAKEPPAPRAARATRTPVAPSPTALGGTTSAAPAAPARR-----RGLECSECKKLFSTETSLQVHRRIHTGERPYPCPDCGKAFRQSTHLKDHRRLHTGERPFACEVCGKAFAISMRLAEHRRIHTGERPYSCPDCG------KSYRSFSNLWKHRKTHQQQHQAAVRQQ-------------------------LAEAEAAVGLAVMETAVEALPLVEAIEIYPLAEADGVQISG---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BY46-1", "uniprot_id": "ZN574_MOUSE", "id": "Q8BY46-1", "name": "Zinc finger protein 574", "aln": "MTEESEETVLYIEHRYVCSECNQLYGSLEEVLVHQNSHVPQQHFELVGVADPGVTVATEAASGTGLYQTLIQESQYQCLECGQLLLSPSQLLEHQELHLKMMAPQEAVPAKPPPKVPPLGSS--AIHYECVDCKALFASQEMWLSHRQTHLRATPN-----------------------KAPAPVVLGSPVVLGPPVGQARVAVEHSYRKAEEGGEGAAVP----------------------------SVAATT-EMVTEVELLLYKCSECSQLFQMPADFLEHQATHFP--------------APVPEAAEPATQQET------QVPSPTEAAVSQPEPLPASDHSYELRNELRNGEAIGRDRRGRKPRRNNSG---ESGGAATQELFCSACDQLFLSPHQLQQHLRSHREGVFKCPLCSRVFPSPSSLDQHLGDHSSESHFLCVDCGLAFGTEALLLAHRRAHTPNPLHSCP-CGKTFVNLTKFLYHRRTHGAGGVPLPTTPVPPEE------------------------------------PAISFPEPAPAETGELEAPELPVCEES---------------------------------SAEPAAPGSYRCLLCSREFGKALQLTRHQRFVH-RLERRHKCSICGKMFKKKSHVRNHLRTHTGERPFPCPDCSKPFNSPANLARHRLTHTGERPYRCGDCGKAFTQSSTLRQHRL-VHAQHFPYRCQECGVRFHRPYRLLMHRYHHTG--EYPYKCRECPRSFLLRRLLEVHQLVIHAG-RQPYRCSSCGAAFPSSLRLREHRCAAAAAQAPRRFECGTCGKKVGSAARLQAHEAAHAAAGPGEVLAKEPPAPRASRATRTPVAPSPTALSGTTSAAPAAPARR-----RGPECSECKKLFSTETSLQVHRRIHTGERPYPCPDCGKAFRQSTHLKDHRRLHTGERPFACEVCGKAFAISMRLAEHRRIHTGERPYSCPDCG------KSYRSFSNLWKHRKTHQQQHQAAVRQQ-------------------------LAEAEAAVGLAVMETAVEALPLVEAIEIYPLAEADGVQISG---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZN55-1", "uniprot_id": "ZN574_HUMAN", "id": "Q6ZN55-1", "name": "Zinc finger protein 574", "aln": "MTEESEETVLYIEHRYVCSECNQLYGSLEEVLMHQNSHVPQQHFELVGVADPGVTVATDTASGTGLYQTLVQESQYQCLECGQLLMSPSQLLEHQELHLKMMAPQEAVPAEPSPKAPPLSSS--TIHYECVDCKALFASQELWLNHRQTHLRATPT-----------------------KAPAPVVLGSPVVLGPPVGQARVAVEHSYRKAEEGGEGATVP----------------------------SAAATTTEVVTEVELLLYKCSECSQLFQLPADFLEHQATHFP--------------APVPESQEPALQQEV------QASSPAEVPVSQPDPLPASDHSYELR----NGEAIGRDRRGRRARRNNSG---EAGGAATQELFCSACDQLFLSPHQLQQHLRSHREGVFKCPLCSRVFPSPSSLDQHLGDHSSESHFLCVDCGLAFGTEALLLAHRRAHTPNPLHSCP-CGKTFVNLTKFLYHRRTHGVGGVPLPTTPVPPEE------------------------------------PVIGFPEPAPAETGEPEAPEPPVSEET---------------------------------SAGPAAPGTYRCLLCSREFGKALQLTRHQRFVH-RLERRHKCSICGKMFKKKSHVRNHLRTHTGERPFPCPDCSKPFNSPANLARHRLTHTGERPYRCGDCGKAFTQSSTLRQHRL-VHAQHFPYRCQECGVRFHRPYRLLMHRYHHTG--EYPYKCRECPRSFLLRRLLEVHQLVVHAG-RQPHRCPSCGAAFPSSLRLREHRCAAAAAQAPRRFECGTCGKKVGSAARLQAHEAAHAAAGPGEVLAKEPPAPRAPRATRAPVA-SPAALGSTATASPAAPARR-----RGLECSECKKLFSTETSLQVHRRIHTGERPYPCPDCGKAFRQSTHLKDHRRLHTGERPFACEVCGKAFAISMRLAEHRRIHTGERPYSCPDCG------KSYRSFSNLWKHRKTHQQQHQAAVRQQ-------------------------LAEAEAAVGLAVMETAVEALPLVEAIEIYPLAEAEGVQISG---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BI66-1", "uniprot_id": "ZN526_MOUSE", "id": "Q8BI66-1", "name": "Zinc finger protein 526", "aln": "---MAEMVAEAAEIPTQSS-GAVEISTAVSGELAEMATAVTEMTSGEALASS----------------LFFQHHQFMCSECGSLYNTLEEVLSHQEQHLLTMSEEETLTTQDAGLEPELVPSTGEGPFQCGECSQLILSPSELLAHQDAHLQESAS-----------------------QIQYQCGDCQELFPSPELWVAHRKTQHLSSAADEPPSPLPPP---TP---------------------PPPPPPPPPPPPPEVKMEPYECPECSTLCATPEEFLEHQGTH-------FDSLEKEEHNGLEEEEEDEEEGEEEEDDDDEETDEEEASSELTADDTGSNKSTADSAQSCGDCPQHCTSSGARHKHRRAS---HGPASATHAFHCSQCQRSFSSANRLVAHGRAHVGGTHECTTCSKVFKKAASLEQHQRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFLYHRRTHTGKSGTPTR------------------------------------------------VATVSPAPAEPTPP-----------------------------------------PLP--PPAQLPCPQCPKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLVHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGVRPYQCLDCGKRFTQSSNLQQHRR------------------------------------------------------------------------------------------------------------------LHLRPVAFARA---------PRLPITGLYNK-------------------------------------------------------------------------------------SPYYCGTCGRWFRAMAGLRLHQRVHARAR-------------------SLTLQPPRSPSPVPPPPPEPQQ------------------------TIMCTELGETIAIIETSQP-LALEDTLQLCQAALGASEASGLLQLDTAFV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TF50-1", "uniprot_id": "ZN526_HUMAN", "id": "Q8TF50-1", "name": "Zinc finger protein 526", "aln": "---MAEVVAEVAEMPTQMSPGAVEMSTPMSAEMMEMSTEVTEMTPGEALASS----------------LFFQHHQFMCSECGSLYNTLEEVLSHQEQHMLAVSEEEALTTQNVGLEPELVPG-AEGPFQCGECSQLILSPGELLAHQDAHLRESAN-----------------------QIQYQCWDCQELFPSPELWVAHRKAQHLSATVAEP--PVPPP---LP---------------------PPTPLPPPSPPS-EVKMEPYECPECSTLCATPEEFLEHQGTH-------FDSLEKEERNGLEEEEEDDEEDEE----DDEEMEDEEAMAEVGDDAVGGDESTAGWAQGCGDCPQHQPSAGARRQHRRTA---HSPASATHPFHCSQCQRSFSSANRLQAHGRAHVGGTHECTTCSKVFKKAASLEQHLRLHRGEARYLCVDCGRGFGTELTLVAHRRAHTANPLHRCR-CGKTFSNMTKFLYHRRTHAGKSGAPPT------------------------------------------------GATAPPAPAEPTPP-----------------------------------------PPPPAPPAQLPCPQCSKSFASASRLSRHRRAVHGPPERRHRCGVCGKGFKKLIHVRNHLRTHTGERPFQCHSCGKTFASLANLSRHQLTHTGARPYQCLDCGKRFTQSSNLQQHRR------------------------------------------------------------------------------------------------------------------LHLRPVAFARA---------PRLPITGLYNK-------------------------------------------------------------------------------------SPYYCGTCGRWFRAMAGLRLHQRVHARAR-------------------TLTLQPPRSPSPAPPPPPEPQQ------------------------TIMCTELGETIAIIETSQP-LALEDTLQLCQAALGASEAGGLLQLDTAFV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA70RF73-1", "uniprot_id": "A0AA70RF73_DANRE", "id": "A0AA70RF73-1", "name": "", "aln": "---MSE--QEFVEHQYMCSECQQLFNTLEDVLVHQQIHTGAEEVEVLPSLED----------------CDPTESQYQCLECGAILRNPDELLLHQELHMREAGQELCEVTEVDAVDAEVPIQ-----YQCLECLALFDTPELWLAHRQTHSRSSTHSSLSAGTEYVLQPDGSVTPIQLLNVQNLVLDEQRAGQILTLAQALREQETPSKASAPPRTMLVPANTSLPGSTSAMLRLQFCSAQAIADGSAPSTLRKAKLLSPLLPAEPIRLDNVTTLNLLPSSGQVNAVKKENEEILIIHPYECSECNLLFSTPEDFLQHQG-EHFLGQDKETGDTGVMVGYEDSLGAKDDEGRSDGSEEGKVGRVSGGRRMYTARSAGLGLTSPVSPSSLRCEECNRTFTSANRLVAHLRVHEQGTHECPECDKVFKKLVSLQTHMRTHSGEARFLCVDCGHGFTTEMTLMIHRKSHTSEPLHKCPFCAKTFTNMTKFLYHRRTHRVREPTTPVSQFVLAQQSPVSIIQRAREREAAWRKDRQMLTIPSKDESSDAGPVLIEGITVVSQSTEPTENGLYVEPSNTEQTQNGGKRLADDPNYLTIAKNEGGGVEDKRMVPATEEDPKFPCSICGKRFSSQVRLLRHRRTTH-TTERRFKCNICGKPFKKQIHLRNHLRTHTGERPFQCSVCGKTFSSLANLSRHGLTHTGVRPYRCDICHKAFSQSSNLRQHRQHLHSNVTPSPCPDCSATFIRPAKLVAHRFLHHPGSPAPYPCPHCTEGFLRKRQRDVHCLEEHPCLAQPHSISQESQGRGQEGSADDTEQQSGSSIPKPNLDCTICGKRLNSPANLRLHQLSHGLG---------PGRPRGSSSNTGKSHPCPVCGKLFVSASSVTLHQRVHTGERPYPCAICGKRFRQNTHLREHLRTHSGERPFRCEFCDKGFVQSMHLAEHRRTHTGERPHACGECGKTFKTISNLRTHRKTHSRSQKQQESEHSGELSATGTNTVAVAVLEASEMDLANSVPDFGQQGVQLGQPQVIQIQTSNLTQTPGTPTIMCNEFGETIAIIETSG---DLTEAIELYRTALEGGINMEAITVDNLQLM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * * .: . : : : . . *: * *** : . .::* *** *: . : :: . : ::* :* *: : * *:::* : :. : . : * : . . . : . : : * * . : .: : . * : : . :. . .. * : :. :. : *. *:: * *.::* * * * *..:*. *.:** . **: * * .*:::****** .* ** *: **::**.:*** * *.*** *:********** . . .. . . * * * : *.. :* **:* .* ***.:*.:*** *** *:************* * *.*.* * ***:** ***** ***:* * * *:***.*:*** *: : :.. . * * . *. * **: * * *:: *: : : . . ** : * . :*::**: * ::::: * . ", "identical_positions": 156, "similar_positions": 142, "identity": "14.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-266", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KLH6-1", "uniprot_id": "CE162_RAT", "id": "Q4KLH6-1", "name": "Centrosomal protein of 162 kDa", "aln": "MAH-YSKVDLDEEFERFMKE-LSDDSFENSNETPSQPNKDRK----------KKDTAPWWIAEDGFEDD----GLLGTNVSYLKTKKTYQPITDMEEE-NEKVQFLKSSGTS---VLSVDSLEANELVASELHHSTLGLGLDTLEEQEEKEQFFARLEKGLTSSIDYSKLNQELDSDDSAQFRVLHRYQGNVEPAEGGRENESEHKELPETYSDDFEDAEDTDEPLITKDEETRPKENPESGKGSFPNQEEEKTGMLANVVLLDSFDSVEDVDLNNHERPTPKAKALPEMAGGELAETG---VSYGQSSG-DTEALHQAYHHVAHSLGDTGEPRIEASPGHSVRSSAKDGLQENEESSKNISTTESDLPTVEELMKPIRIDSYGIRGFDLQPVSLQKAVGSKEAESVSSLPLTVNTNTMSQDTRHVSPFPHEQDESVVLHRTAGEGVGSSCP------ATEEHLDKMYLEILRKKTSVNPSLLPQDNKANQTSRSRLSAREEAPVTSKQVPCKKARSAPPLPRRKPQSGLYASARSSGYSKPSSPLQFFSALEKKTSKDNTKTKNVRPIPTSNQFRKREILSGTKLIKPAALNKPSPHREGSPATPKRPEDPSD-DSFVQLQTETLGSYGGNREKELLMLKRAQDAEEKWRGAQALIEQIKMTFSEKEKELENTVESLKRQQERELFKLNQENYILQAKLSSFEETSRKQRWLQFGETSDPLTEEKLKQIQKEIQEQETLLQGYQQENERLYSQVKDLQEQNKKNEERMFKENQNLFSELASLKEQMHKNHFLPQAVENIEPTKNQSFTDLLAELRAAQKEKNHLMEDIKRLKQDKQALEVDLERVKRERDQAKDQIAYTTGEKLYEIKILEETHKQEVSRLQKRLQWYAENQELLDKDAARLREANEETERLKLEIEKLKTESGSPANQQRLRSKERALDAKRIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDSVDRN----------TVDFMERRIKKLEADLEGKDEEAKKSLRTMEQQFQKMKIQYEQRLEEQEQMLAHRQREAPQNQ-HNSSSRLKALETELGGIKEAHQITVRKLEAEIDVLKHQNAHLEHKKNDKEDQDLQSIEFQVEQAQARAKLARLNEELAAKGREIQDLTKTVERLQKERRMMLSRQSPRGREEMAAKRLKKEILHPNSGNANAFSETLGAKLYHPHTFTDSHISEVLEENYRLRSELEGLTLEREKLKMESEAAVCQLESSMKRVKDDAAAHIASLKAAHEREIEKLLCQNAVENSSSRVAELNRKIATQEVLLKHFQGQVNELQGKQESLSLSQVREEILQKQITKLLEELKEAKENHTPEMKHFMGLERKIKQMEMRHKQREQELQQIIQQTRQVVETEQNKEVEKWKRLAQLKNRELDKFRTELDSILDVLRELHRQGVVVPVALADEESTAKEF----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZQ06-1", "uniprot_id": "CE162_MOUSE", "id": "Q6ZQ06-1", "name": "Centrosomal protein of 162 kDa", "aln": "MAH-YFKVDLDEEFERFMKE-LSDDSFENSNKTPRQPNEDNKEMK-------KKDPVPWWIAEDDFEDD----GLLGTNVSYLKTKKTYQPVMDTEEESAEKVQFLKSSGTS---ILSVDSLEANELVVSEPHHSTLGLGLDTLEEQEEKEQFFARLEKGLTSSIDYSKLNQELDSDDSAQLKALHRYPRNTEPAEDGCENESEQEELPETYSDDFEDAEDADDPLITKDEETHPKENSESGKDSFPKQEEEKTGMLANVVLLDSFDSVEDVGLSSQEKATPKAKAPPEITDDGPAETG---VPYGQSSG-DTEALHQAYCHVAHSLGDTGEPRIEASTVQTVRSSIKDGLQENEESSKNVSTTESDLPTVEELMQPIRIDSYGIRAFDLQPISLKKATDSKEAESVGSLPLKTNTNTVSQDTRHAIQFPHKHDESVVLHRTADEGMGSSCP------ATEEHLDKMYLEILKKKTSVNPSLLPQDDKMNQTSRSQLGAGEEVPVIGKQVPCKKARSTPSLPKRKPQSGLYASARSSGYGKPSSPLQLFSALEKKTSKDNTKTKSVRSIPTSNQFRKREILSGTKLIKPAASNKPSPHREGSPATPKRPEDPSD-DSFVQLQTEPLGSYGGNREKELLMLKRAQDAEEKWTGAQALMEQMKMTFCEKEKELENTVESLKRQQERELFRLNQENYILQAKLSSFEETSRKQRWLQFGETSDPLTGEKLKQIQKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQNLFSELASLKEQMHKNHFLSQAVENTEPTKNQSFTDLLAELRAAQKEKNHLMEDIKRLKQDKQALEVDLEKVKRERDQAKDQIAYATGEKLYEIKILEETHKQEVSRLQKRLQWYAENQELLDRDAARLREANEETEKLRLEIEKLKTESGSPATQQRLRSKERALDAKRIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDSVDRN----------TVEFMERRIKKLEADLEGKDEEAKKSLRTMEQQFQKMKIQYEQRLEEQEQLLAHRQKEAPQSQ-RNSSSRLKALETELGDIKEAHQITVRKLEAEIDVLKHQNADLEHKKNDKGDQGLQSIEFQVEQAQARAKLARLNEELAAKGREIQDLTKTVERLQKERRMMLSRQIPRSREETAAKRLKKD---PNRGHGNAFPETLDGKLYHPHTFTDSHISEVLEENYRLRSELEGLILERSKLKMESEAAVCQLENSMKRVKDDAAAHIASLKASHEREIEKLLCQNAIENSSSKVAELNRKIATQEVLLKHFQGQVNELQGKQESLAVSQVREEILQKQITKLLEELKEAKENHTPEMKHFMGLERKIKQMEMRHRQREQELQQIIQQTRQVVETEQNKEVEKWKRLAQLKNRELDKFRTELDSILDVLRELHRQGVVVPMALAGEENTAEF-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TB80-1", "uniprot_id": "CE162_HUMAN", "id": "Q5TB80-1", "name": "Centrosomal protein of 162 kDa", "aln": "MAN-CSQEELDEEFEQFMKE-LSDDSFENSDKTARQSKKEMK----------KKDTVPWWITEDDFKDD----GLLGTNVSYLKTKKTSQPVMEIEEESAEKIQFLKSSGTS---LLSTDSLETNELVVSELNHSSLGVGLDTLEEQEEKEQFFARLEKGLTSSIDYSRLNKELDSNDSTHFKALHSNQANAELTDDEHENESKHEELAENYSDDFED-EYVGAPLTTKDEEMPSKENSKSEKISVPKQEEEKTGMLANVVLLDSLDSVAEVNLDEQDKITPKPRCLPEMTENEMTGTG---VSYGQSSS-DVEALHQAYCHIAHSLGDEDKQKIESNTVEDIKSSVKGHPQENEENSKNISTMESDLPTVEELMKPIRIDSFGISGFDLQPVSSEKVAERKETEFFSSLPLKMNPNILSQDSQHVNLFFDKNDENVILQKTTNESMENSCPQVTEVTATEEHVDKMYLNILRKKITVNSSSLSQDDKINKTYRSQLSSEEEGAVMGKQVPYKKARSAPPLLKRKPQSGLYASVRSSGYGKPSSPLKMFSTLEKKTSEDIIKSKNLRSISTSNQPRKKEILSGTKLIKPAALDKPAHKTESCLSTRKKSENPTETDSCIQFQTDSLGYCGENKEKKLLMFKRVQEAEDKWRGAQALIEQIKATFSEKEKELENKLEELKKQQEKELFKLNQDNYILQAKLSSFEETNKKQRWLHFGEAADPVTGEKLKQIQKEIQEQETLLQGYQQENERLYNQVKDLQEQNKKNEERMFKENQSLFSEVASLKEQMHKSRFLSQVVEDSEPTRNQNFTDLLAELRMAQKEKDSLLEDIKRLKQDKQALEVDFEKMKKERDQAKDQIAYVTGEKLYEIKILEETHKQEISRLQKRLQWYAENQELLDKDALRLREANEEIEKLKLEIEKLKAESGNPSIRQKIRLKDKAADAKKIQDLERQVKEMEGILKRRYPNSLPALILAASAAGDTVDKN----------TVEFMEKRIKKLEADLEGKDEDAKKSLRTMEQQFQKMKIQYEQRLEQQEQLLACKLN-------QHDSPRIKALEKELDDIKEAHQITVRNLEAEIDVLKHQNAELDVKKNDKDDEDFQSIEFQVEQAHAKAKLVRLNEELAAKKREIQDLSKTVERLQKDRRMMLSNQNSKGREEMSAKRAKKDVLHSSKGNANSFPGTLDSKLYQPHTFTDSHVSEVLQENYRLKNELEGLISEKNELKMKSEAVMNQFENSMRRVKEDTAAHIASLKASHQREIEKLLCQNAVENSSSKVAELNRKIATQEVLIRHFQSQVNELQSKQESLVVSEVREEILQKEITKLLEELREAKENHTPEMKHFVGLEKKIKQMEMRHAQREQELQQIIQQTHQVVETEQNKEVEKWKRLAQLKNRELEKFRTELDSILDVLRELHRQGVVVPVAFADEMNAPEY-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F5E1-1", "uniprot_id": "CE162_DANRE", "id": "E7F5E1-1", "name": "Centrosomal protein of 162 kDa", "aln": "MAHRLTKEELDQQFEQFLKESVSDDSVDLGTSSKRPSVLDSLGKAPVRPVKKASASVPWWQDDDDNDDDSEEKGMSSTGRSFLKSLRKTPSIKEVDEE-QPKELFLEDEGNRDHVILSRDSLEPEDSLVIP---SAGARGLDTLDEDDDDARFLSNLKKVSSSSIDFSRINREQE--LSAPTSPLRREEMDSTIEEEQRMN--KDTAASPAYSEDFEEEASDKS-------DVEPQE-----------KKPERLGMLAKVSLHDSLNSTDGALAPAVPSLAVARENRPESKQTDMPALEPAVQSYGQSGGSEMEALQEAYRQISGSAGVCEDGQVEAGRTPLSLSTLQP-----------ASTVESDLPTAEELMQPIGPDSGFTRGFSLQPIT-EAVPRSRDNQ--SPLRISSDESPFSSAN-------EGYGGGNTANLTGGEHPDSYKF-------TQKSISEEIRRLMQEQDTSSQEPPPLKPKKRQVPAR---SNASTSASSRKAPVPSVRVKK--PESKPLHRVPAPSRAAQAAKPPSP----PTLRKAQNQTFKKTQNLNQTHTIKGLDTSLKLSSELVESVQSFAAFLQHQVEASSLQDKGPFQAN-----KIASEAMTAHKG-------MQEKMDGGPE-----LASLERLRLQLAKKERELSLREDQLQEQHKQELTALRQENYILQSKLHRAEEASNKRKWS-FGEASDPVTEEKLKLIEKEMKEQETLIQGYHQENEKLYLQMKALQAQSKQNEEALFMENQRLLTELSFARDRMNTNNIQRTIRERSIVDQSFNIAELTSQVQAAQKKEERLQEEVRRLKQEKQALHVDLEMMRKERDLAKVQAVCKSGDKGFELKLLHDKHREEVTELKKRLQWYAKNQELLDKDAARLHAATAEIQKLTEQVEKLKAEVSRRANEQQRKAKEKAGEAKRIQDLERQLKQKEELLKRRHPNSLPALILAAASTGAEEDRLDVRSLAQSSQTAALLERRVHRLEAELEGRDEAAKRSLRAMEQQYHRIKLQYEQQISDLEQRLSEKSHSYPAISSELIKSHTQTLKAELEEVKEVHQKQVSVLQAEVDSLQEQLRQAQASTQTEKPARSPSRHQLHAEAAQAARIERLTQELNSKSRSIQELTRTIERLQRERRTMLSGP-SHERPNNEPKRHLGTAKDTKKPSVETFPPTQDEKDYHPGAFSGTHISEVQLENDSLRTKLEELEVLREKEKVSLQAAVTHAQNQLLRIEEQNAEQLTSVKAEHRKEIEHLLARHALEHSSSRVAELTSQLNTQEIIVQHLQGQVKELQGTKEALAVTKLREETLQNQLSKLLEELKEAKEAHSPELKHFTSLEQKIQSMEFRYSQREKQLQQVIADTRRVVEQEQQSEVERWRKLAQGRAKELEAFRMELDSILDVLRELQRQGVVIPMPEHTSTNTHTYLPLRS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W474-1", "uniprot_id": "Q9W474_DROME", "id": "Q9W474-1", "name": "Centrosomal protein of 162 kDa", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQVLSPHKQGVSEADALDYTNSS---------------SIIEFLAKEQDCGGILNDPDPESIFQEVSR-----------------LSDSTDMRSVDELLQEAER------------------------------------------------------------------------------------------LIQQQLRLGGIVPKLDASGPPAPTKTLGEEAATGGDGS--------------SSSPQSSPHSSIRLN---------------TRYTHRIEHSPAPLAPKTVAVNGRVRPRSGSKSSASPTSVQTPLESSNGCGFAAFVDNLPSA-------------------------------------------SVISEESTPKDMDMENHTAAMAKLQLQQLQDNTDDDEDTMEEITEAEVDAP------------------------------------------IFSRAEDTGKEVRSPPERQFKSQGRSYIQPSQPIRPMAS--YSEKAVGSSPKRMVSTLTSPIEQIASSVSREHALKLEIEQLQERLKDTEERLASVRLQSD--------SLSQTQRALREHNSRLQEESEMLKLDVQHLNECANVLR---SELQAARRDRGEALQMQRSLRDELEEANQERRRTGEGKEKDSRVIQDLQRQCREMERILMRKHPDSVSALIVASKSSGMCPLNDQ-----ENVNSRKLLEQRIAQLESDAKEQDRKAQQILANVQARFNSVQAKYETHIADLETQVLSLQEINTKLN-EQIESQVRTLDRYMQKRADRYYNNCTQTEPLEEDDVSVGGGVNHGRATPVSSNTMGTQTQAANGTRDHSTNTIGCPSPALVCQQQHLHQAHGHLHPHAPSASSSTSSTANSTPNTSRPNSK----QSGGQRRSPLVTAGPSKLPISQSDSTLSLLSHGGGGSKEEAQLLSSVRSMR--VDLAIKNKAMQRLTRELDECKKTIRKLQRDKEGSGSGSQTGSKLDLRSQASGGAMQQRRSSGYDHHHHSDHIPAATESQALKEAQNKYRLLEADYKTLHDKRLQDLKTLQSAHERELASCNETVRILQQRLNEREEALTTQKRRKVPVDYYALKAKVSLLERRHSEREE-------RLHMLVEALSKGRLNGALEDLMQENNNK---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .* . :: : : . * . *: : .:*: :.:**:: ::::: . . . . . .* :. * : . .. : . .. . : . : . : *: ::. : . : ::* ::: :: * :: : : : :. * * .: : : * . .::. :: : ..:. * ::.:*:: : . : :: : * .:. :: .. ::* *: :* : ::* .*: * : . ..*: * .:: : : ::: ****:** :: * :* *::*:*:.***:*: ::* . : ::*:*: :**:: : :*. *:: * :: ::: :: :** :: : * : . . ..: ::*. : : : :. : : . . :. : : . *.* :: :*: . * . . ..* . . . . * : :.: :* : . : : : * :. * : . : * :: : .:: :. . . :: *. . : :. :* ..:: .: : . . : :.*:: * ::.. :.: . :..:: :: * :**: * . * : :*. .: . : . .*. :::.* : : :*.: : . . ", "identical_positions": 75, "similar_positions": 287, "identity": "5.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-270", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P04062-1", "uniprot_id": "GBA1_HUMAN", "id": "P04062-1", "name": "Lysosomal acid glucosylceramidase", "aln": "MEFSSPSREECPKPLSRVSIMAGSLTGLLLLQAVSWASGARPCIPKSFGYSSVVCVCNATYCDSFDPPTFPALGTFSRYESTRSGRRMELSMGPIQANHTGTGLLLTLQPEQKFQKVKGFGGAMTDAAALNILALSPPAQNLLLKSYFSEEGIGYNIIRVPMASCDFSIRTYTYADTPDDFQLHNFSLPEEDTKLKIPLIHRALQLAQRPVSLLASPWTSPTWLKTNGAVNGKGSLKGQPGDIYHQTWARYFVKFLDAYAEHKLQFWAVTAENEPSAGLLSGYPFQCLGFTPEHQRDFIARDLGPTLANSTHHNVRLLMLDDQRLLLPHWAKVVLTDPEAAKYVHGIAVHWYLDFLAPAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVVGWTDWNLALNPEGGPNWVRNFVDSPIIVDITKDTFYKQPMFYHLGHFSKFIPEGSQRVGLVASQKNDLDAVALMHPDGSAVVVVLNRSSKDVPLTIKDPAVGFLETISPGYSIHTYLWRRQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P17439-1", "uniprot_id": "GBA1_MOUSE", "id": "P17439-1", "name": "Lysosomal acid glucosylceramidase", "aln": "--------------------MAARLIGFFLFQAVSWAYGAQPCIPKSFGYSSVVCVCNASYCDSLDPVTLPALGTFSRYESTRRGRRMELSVGAIQANRTGTGLLLTLQPEKKFQKVKGFGGAMTDATALNILALSPPTQKLLLRSYFSTNGIEYNIIRVPMASCDFSIRVYTYADTPNDFQLSNFSLPEEDTKLKIPLIHQALKMSSRPISLFASPWTSPTWLKTNGRVNGKGSLKGQPGDIFHQTWANYFVKFLDAYAKYGLRFWAVTAENEPTAGLFTGYPFQCLGFTPEHQRDFISRDLGPALANSS-HDVKLLMLDDQRLLLPRWAEVVLSDPEAAKYVHGIAVHWYMDFLAPAKATLGETHRLFPNTMLFASEACVGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVTGWTDWNLALNPEGGPNWVRNFVDSPIIVDIPKDAFYKQPMFYHLGHFSKFIPEGSQRVALVASESTDLETVALLRPDGSAVVVVLNRSSEDVPLTISDPDLGFLETVSPGYSIHTYLWRRQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7EZM1-1", "uniprot_id": "E7EZM1_DANRE", "id": "E7EZM1-1", "name": "Glucosylceramidase", "aln": "------------------MRETALFILLAGIITTARADSKDGCLALNFGHGSVVCVCNATYCDSLGRTVLPDAGQFLSYVSNKAGSRLMESQGQFQKNSTGAALRITLNPSQKFQHIKGFGGAMTDAAAINILSLSSGAQDQLLRQYFSTDGIEYRFVRVPVASCDFSTRLYTYADTPEDYDLQNFTLAKEDVHMKIPLLQRAQALSAQPLYLFASAWSAPAWLKTNGALIGKGSLKGKPGGKEHKTWAQYYIRFLEEYRKYNLSFWGLTSGNEPTAGEMTNYSFQALGFTPETQRDWIALDLGPALHSSSFSKTQLMILDDNRLMLPHWAKVVLSDIKAARYVHGIGVHWYFDRLVPPDVTLTSTHHLYPDYFLFATEACAGWSPVDRGVRLGSWDRAEDYAHDIIQDLNNYVTGWTDWNLALNQDGGPNWVKNFVDSPIIVDPSKDIFYKQPTFYSMAHFSKFLWEESQRVGVSFSQQTSLEMSAFIRPDASAVLIILNRSEEEVPFEVWDQTVGFLPGSAPPHSILTLLWNRQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : : : :.: * . *:. .**:.********:****:. .:* * * * *.: * *: * * :* * **:.* :**:*.:***::**********:*:***:**. :*. **:.*** :** *.::***:****** * *******:*::* **:*.:**.::****:::* :: :*: *:**.*::*:****** : *******:**. *:***.*:::**: * :: * **.:*: ***:** ::.*.**.****** ***:*: ****:* .*: ..:*::***:**:**:**:***:* :**:*****.****:* *.*...** .**:*:*: :***:***.* . ::.********. :*:*.** :* :*.********** :******:********** .** ***** ** :.*****: * ****.: *:...*: *:::**.***:::****.::**: : * :*** :* :** * **.**", "identical_positions": 273, "similar_positions": 155, "identity": "50.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-272", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VHW3-1", "uniprot_id": "CCG6_MOUSE", "id": "Q8VHW3-1", "name": "Voltage-dependent calcium channel gamma-6 subunit", "aln": "MMWSNFFMQEEDRRRTAVGRRRAQEQ--QNLG-------LTPEREGKIKLGLLVAIVGATLAVLAVGTEFWVELNTYKTN-GSAVCEAAHLGLWKVCIKRLWQADVPAGRETCGPAELPGEANCTYFKFFTTGENARIFQRTTKKEVNLAAAVIAVLGLTAMALGCLCVIMVLSKGAESLLRLGAVCFGLSGLLLFVSLEVFRHSVGALLQGVNPETPPAPRLAYEYSWSLGCGVGAGLILLLGGVCFLLLTLPSWPWRSLCPKWGGPTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXT2-1", "uniprot_id": "CCG6_HUMAN", "id": "Q9BXT2-1", "name": "Voltage-dependent calcium channel gamma-6 subunit", "aln": "MMWSNFFLQEENRRRGAAGRRRAHGQ--GRSG-------LTPEREGKVKLALLLAAVGATLAVLSVGTEFWVELNTYKAN-GSAVCEAAHLGLWKACTKRLWQADVPVDRDTCGPAELPGEANCTYFKFFTTGENARIFQRTTKKEVNLAAAVIAVLGLAVMALGCLCIIMVLSKGAEFLLRVGAVCFGLSGLLLLVSLEVFRHSVRALLQRVSPEPPPAPRLTYEYSWSLGCGVGAGLILLLGAGCFLLLTLPSWPWGSLCPKRGHRAT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9M5-1", "uniprot_id": "E7F9M5_DANRE", "id": "E7F9M5-1", "name": "", "aln": "-MWSNFFLQQDDDGRGGMGALGGAGSKSGRTGKRARPPRMSDSEEGKIKLAFFLVLIGVTLTVLGMGTEFWVELSQPKHFRNNQTCEMAHYGLWKSCVRTLWVTDIDPERESCGPAELPGESNCTYFKFYTSGENAVIFKKTTQKSLHIAGAMLALLSLFMMVMGSVCITMSISKSVPFFLKPATICFVCSGILVLLSIIVFHQSILALLASDHSIP-----LHHELSWSVACVGSSGAILIIGGLIFLLLSLPYNPLEKCFRQQSSSDA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******:*::: * . * . . . * :: ..***:**.:::. :*.**:**.:********. * .. .** ** **** * : ** :*: *::*********:*******:*:**** **::**:*.:::*.*::*:*.* *.:*.:*: * :**.. :*: .::** **:*:::*: **::*: *** . . * :* ***:.* .:* **::*. ****:** * . : . :", "identical_positions": 109, "similar_positions": 83, "identity": "40.37%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-275", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B7Z043-1", "uniprot_id": "B7Z043_DROME", "id": "B7Z043-1", "name": "", "aln": "MPVIADAASDEPPAKCCKHCEESTQSVDGGPASWRLTLDQDLIDTLKGNFPSWFQGSAGGGGGAGGAASKQNPQQHNHQLAQQKHHQLVATSVIPITIDTKLAASNTNTLQQHQQQTAILGHSSSSASPASSVSSNSSKKSISSSLSSCSSSSSNSSSCGSNHCNSKSVSSGAKGAGSATASRFLNKSTSTSPTKSLSRTLKATQKPNGNHKVGQLVKSASLHSLSSGSSGSSSGNSASGSSSLLATISTSPLTTVELISSAACSGLLATRLSGKDLEHSFQDIILLHEAYDDMSEGEQRLHATFLGSSDDGNNSDCYDARQSPPKAIVDSSPLQPAMDKNKESLKVKLMVRRPHSQLVEQGIIPSLKTSPAIHEQCKQLERAKTSDLLKAKIQQRPNREDLERLHILEEDECHIDPSLAEKQRMLKKARLADQLNSQIQHRPGPLELIKKNILHTEKPIEKIVKEGLVSFKATSEGLLTRPQHPHSYVTFDDDSLSSESDTRQTPPRLDEAMVATSSSPTDVLQAAAASAGIVTMALTMPTAGQLVVTSPQILPQQQQPKAIVVPAPVPPPPPPPPPLPMASIIKVKQETANLYEELCQSVTGTTASPVNHLYSPCSLASSTSTLSPLSSIASPPPPPMTTTRLHLAPVSVKSDAPGKDKNRKKSKSKPVSKARTIKFHEYKGPPSAAGQKQDQTQPEETSYQLMLEQQNCLLKFLENLNKNQSIIPAPSAPGVMLPAAPGATNNSITVTTKTVPALASQSAPAPAPISLPNTISITSSSGGAPLNFGDATMLTPTPAATPTPPTLSLIAAPQQQLQLHQQHQQLHQPTPVQHPPPLPSPALSVSSSIPPSPATSYAESTTSSITDLARLEKMKVSDLKQHLKRRNLPVSGPKPHLIERLKPYLPLEPLDSNVTPAPTSNNSNTTPEVITISDAMDTSNCGLLEQPPPVTMLVSDASMEHEQMDVVQQQMDNTHPMTLQTILPPQPQTATIILTNEELLREQQRKIDELQRQLQRSQQELQKIRQRQQQQQHQQQQTVTAQVVNALPSQQITLITTTSNGPQQTLTVMPQQVEKNFPAKVTVKATGGNSNHKVNGLQQQGSAAKKPASSNSNSNSNISSSNPPPINQKMVVKQQLEAKIQKQKAAAAAAAQQQQQQQQQQQQQQQQQALQQQQQQQQQQQQVRLLTQKTQTVFIPFNNNNHINNASAKTTTKKSNVPANNTNTTTATMMQAAKPAAVAAAAASPGNQHHNNLGLLWNEGNQTILLLGLNDQHMTAHTLGNISLTATTTTTAAPPAATPVAASTIAPPKKILNGHQRTNSLPSIVFPIETKSIITQQQLQQLQQQQQQQQQFQPVQQPKQQQLNQVDIKPAPAPPPQYEEATKQLAASKAAALNGLLPLVKIKEEPVQSPAPSAAPLPQTAPLCKRKTASIKSEQVSDVLDILIKQGELPESAALEPITPLTPLPELSMFNGATPTTAAGGASIVPLVPKLETPVTPVQNLDVAMDTNVQHVGFASNQAPNHVFIESIDMASPLQTDSSAIDAESVAKTLDIFLEQHHATPPPSTPPKSCHSGSEKPNSPDAKLNHFDEYELLELMSQQLEMDMGDDSSGYCHASAAKSSNNNGNLRRDLNPSLQPSINELLDASSPDNVLLNNNTGADVDFDADSFVAQLSQHVTGNGNSPGVNCNGSIESSSSAVNSHFGSHSTPMDCDDFESTLNSFMQAVTQPQAGQHVEYATSTSMANGTGGGMGVDNGTGGAVDAFNASGDIFDLFNMDDYKMNWAAGDFTV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0AA52Z251-1", "uniprot_id": "A0AA52Z251_DANRE", "id": "A0AA52Z251-1", "name": "", "aln": "--------------------------------------------------------------------------------------MTLLASERSLLIRNKFRSVLQLRIQNRRQQNELN----AEAGTKASVPDKTGDKEVSNGLQ--------------------------------------DGSTQKSPPSGLTAQTAPDRSYSGAHRQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KKARLAEDLTEKIQSRPRPLELLQKHILPPEN------------------------TALLPSDVFEDDNSSSASASPEQ--------------------------------LGMHQSPGFSSSSPGQGGDQSLSDVSPVATPISPNN------VQQCRLALLPATECISQPMTMTVTGSNSITTG---RPKGMYMPSQTPPLLPKTAQPPAPPSHS----ILGGSLNSSRPSRPRKPRDSKPK----MRKLKYHQYIPPDQRTG------------------------------------------------TGSGAANASQKNNNSQVPATDSSYSHLLQQQQVFLQLQILNQQQQLPVTNSENNLKTSGSTPQSSP----------------------QSATPSTNPSTPDTSPIHQAELLPSN------------------LDDLTVSVLRQQLRKRGLPVSGTKPALLERLRPFQMPRPP---LTPAPLCQLG---------------------------------------------ATLDQSHPASLN----------------------------------------------------------------------------------------------------LSPTSIDTSSNSTYTGLAEPSLASDGFLTSPSSAGSSPTLHTSSPQLPSGATWRPGQAVDELSVELEMRERIRSRPRDGAKDTQLCGSSLHPFLQQEPGCNRGKAETGGQELLFTYCSGDGKVN--------------CCQLCDAIGQDFDLPMQITASPAQASP---------------------------------------TVRSLEEELQEAIQRVQMDPSQSIDDILDVNIGGSDNSSLVTDIQSAALVVSGFSSALQPDQSQSTKRQKDDNFLSSPLCSSLLLELPPSP----NNTSALCP-----------------TPAPLPPPPICTTPPSTSLSRKRRSEVPAFDPADWLETLTSG--------LHPLTP---------------------------------PAAPFLESDFGLDSDLN-----------------------------------VNRVLDLMVEQW---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* .: * .*: : :*:::**. : :.*.. :**..::..*.:*..*. : **..**...*: . :. .* *: ******::*..:** ** ****::*:** .*: . .*:**. ** * : : * * : : :** :*. ... *.:*:.* . : : * : : : :***:.: ... * .: .:.* . *.. *.**.** : : *::*. *.: :: :.**.* *.:*:*:* * . :* :..**:* * . ... *** *. : .: :.* ... *:. .: .: *. .:. .:* :..** :*.. :..: :. :*.. *:.:.** *:*:*::*.*****.** *:***:*: .* :**** .: . :*::** :*: :: .: . .** . .** : . *:. :* *.:.*. : ...* . .. : :* : . :.: :: :: * .:*: **: :: : * : :* ..:.::* . : : . :: . :.:.* *** *. : * * .. . ..**: : .. .*:* *:: :::.. . ** :*.*. : * :: .. * . : *..* : *. *.. *. *.*. .. * ::.*.::: :.: : : :* *: * . *.*:** *.:*. : *..:*:::: * :.**:::** ", "identical_positions": 180, "similar_positions": 313, "identity": "10.07%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-280", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05540-1", "uniprot_id": "CD4_RAT", "id": "P05540-1", "name": "T-cell surface glycoprotein CD4", "aln": "MCRGFSFRHLLPLLLLQLSKLLVVTQGKTVVLGKEGGSAELPCESTSRRSASFAWKSSDQKTILGYKNK-LLIKG-SLELYSRFDSRKNAWERGSFPLIINKLRMEDSQTYVCELENKKE--EVELWVFRVTFNPGTRLLQGQSLTLILDSNPKVSDPPIECKHKSSNIVKDSK----AFSTHSLRIQDSGIWNCTVTLNQKKHSFDMKLSVLGFAST-SITAYKSEGESAEFSFPLNLG--------EESLQG--ELRWKAEKAPSSQSWITFSLKNQKVSVQKSTSNPKFQLSETLPLTLQIPQVSLQFAGSGNLTLTLDR--GILYQEVNLVVMKVT--------QPDSNTLTCEVMGPTSPKMRLILKQENQEARVSRQE-------KVIQVQAPEAGVWQCLLSEGEEVKMDSKIQVLSKGLN-QTMFLAVVLGSAFSFLVFTGLCILFCVRCRHQQRQAARMSQIKRLLSEKKTCQCSHRMQKSHNLI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P06332-1", "uniprot_id": "CD4_MOUSE", "id": "P06332-1", "name": "T-cell surface glycoprotein CD4", "aln": "MCRAISLRRLL-LLLLQLSQLLAVTQGKTLVLGKEGESAELPCESSQKKITVFTWKFSDQRKILGQHGKGVLIRGGSPSQFDRFDSKKGAWEKGSFPLIINKLKMEDSQTYICELENRKE--EVELWVFKVTFSPGTSLLQGQSLTLTLDSNSKVSNPLTECKHKKGKVVSGSK----VLSMSNLRVQDSDFWNCTVTLDQKKNWFGMTLSVLGFQST-AITAYKSEGESAEFSFPLNFA--------EENGWG--ELMWKAEKDSFFQPWISFSIKNKEVSVQKSTKDLKLQLKETLPLTLKIPQVSLQFAGSGNLTLTLDK--GTLHQEVNLVVMKVA--------QLN-NTLTCEVMGPTSPKMRLTLKQENQEARVSEEQ-------KVVQVVAPETGLWQCLLSEGDKVKMDSRIQVLSRGVN-QTVFLACVLGGSFGFLGFLGLCILCCVRCRHQQRQAARMSQIKRLLSEKKTCQCPHRMQKSHNLI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P01730-1", "uniprot_id": "CD4_HUMAN", "id": "P01730-1", "name": "T-cell surface glycoprotein CD4", "aln": "MNRGVPFRHLL--LVLQLALLPAATQGKKVVLGKKGDTVELTCTASQKKSIQFHWKNSNQIKILGNQGS-FLTKG-PSKLNDRADSRRSLWDQGNFPLIIKNLKIEDSDTYICEVEDQKE--EVQLLVFGLTANSDTHLLQGQSLTLTLES-PPGSSPSVQCRSPRGKNIQGGK----TLSVSQLELQDSGTWTCTVLQNQKKVEFKIDIVVLAFQKA-SSIVYKKEGEQVEFSFPLAFT--------VEKLTGSGELWWQAERASSSKSWITFDLKNKEVSVKRVTQDPKLQMGKKLPLHLTLPQALPQYAGSGNLTLALEAKTGKLHQEVNLVVMRAT--------QLQ-KNLTCEVWGPTSPKLMLSLKLENKEAKVSKRE-------KAVWVLNPEAGMWQCLLSDSGQVLLESNIKVLPTWSTPVQPMALIVLGGVAGLLLFIGLGIFFCVRCRHRRRQAERMSQIKRLLSEKKTCQCPHRFQKTCSPI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6F9-1", "uniprot_id": "A0ACD6B6F9_DANRE", "id": "A0ACD6B6F9-1", "name": "", "aln": "--------MLGLILIPLFITVLKAQESQEVIYAQVGGTVTLPRDKIERKDGNIKTQDIYVNWFLDSENTLIINRNPQISINKGTNARVSLS--ADFSLQISPVEESDFVIWRCEQHVLARNYKKTYKLYKVSIPKVPALLVGGRLFLKYVKDVSSVNPSVTWISPKNEGCQEHKNTKDTVLVPSVSTCHNGVWTCQLKYENKKTEATTTVSVIDLAPSPADPIYTSISQSSTVSIPCALSSAIPWSVLNETLQGGSWSFTPLSEPRSPLSLLTLNVGSVVRWDLANGANFTDGKRVITNHNLSIQNLPVKETIRGVYKCSLKFNTKTISREVKVEVLKVSPSGSLKVFEGTRLNVTCSLGHMNTAGLEVKWTCASNCPPFNHKSPPHLSVLSFPKIRMQDKGLVKCELWKNSQKLTSAQLYLRVEKAPVDIWLCVAIGSGVVVFILLVAFAIIYIRRHKQMMMYRRRKTRFCCCNNNKQ----PKGFYKT----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *: : : . :.: :: .: * :. *. .:: : : :*. ... .: :. . . ::: . ..*.* *. :. .* : ** . . : :: :: . ** * * * . .* .: . * .. .: ... *.* : ::** : *: : : : *.. .:. .*:* : *. * .. . :::.: . : . * : : : : * . :*. : :**:: *::.: : .:**.: .:. : : . .: . ..... . : : *: :* * .. : .:.: : : : .. :: : .: *: * :: * ::: .:*: .: : *: ", "identical_positions": 44, "similar_positions": 160, "identity": "8.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-282", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GL80-1", "uniprot_id": "A0A8I6GL80_RAT", "id": "A0A8I6GL80-1", "name": "", "aln": "-------------------------------------------------------------------MANWWRAFPRAARRYPWPTNVLLYAGLFSAGDALQQRLRGGP-----------------------------------------------------------ADWRQTRR----------------VATLALTFHGNFNYMWLRLLE-----RALPGRAPRTVLAKVLCDQTVGGPVALSAFYVGMS-ILQGK--DDIFLDLRQKFWNTYK----------LTNFSLVPVNWRTAYTGLCGFLWATFLC-FSQQSGDGTVESIFILLRRKEAGDRSPEK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1P841-1", "uniprot_id": "A0A8M1P841_DANRE", "id": "A0A8M1P841-1", "name": "", "aln": "-------------------------------------------------------------------MNRIWTLF----KSHPYIPNVVGYTTLFATADLIQQGVMGKAQDKETEQEVQDTLKTSIERFTVSKEGKTDDLTLYNAKTNDAGNQTLSEMQHVPQFHRSFIDWSQTAR----------------VALVGFCFHANFNYYWLRGLE-----RMFPGGGTKRVSLKVILDQLIAAPMTISAFYIGLS-TLEGA--EDPFEDWKNKFWTSYKTGVVYWSTMQAVNFSLIPPAARTVFVGGVALGWTIFLCHFKQQKSD--VRS-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JNT1-1", "uniprot_id": "A8JNT1_DROME", "id": "A8JNT1-1", "name": "Mpv17-like protein", "aln": "-------------------------------------------------------------------MARLISGVRNLFHRYPFVTNSAIYGSLYVGAEYSQQFASKRWLATASKPED--------------------------------------------------IDYATIGR----------------YAVMGTAVYAPTLYLWYKWLD-----RAFPGTTKVIIVKKLVLDQFVLTPYLLTVFYAGMS-IMEGS--ADIFLELREKFVPTFMRSCIFWLPAQALNFSLVAPRFRVIYMGICGLIWVNILCWTKRQSLPVATKEIATDSNNNAAAIRNSET", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06563-1", "uniprot_id": "SYM1_YEAST", "id": "Q06563-1", "name": "Protein SYM1", "aln": "--------------------------------------------------------------------MKLLHLYEASLKRRPKTTNAIMTGALFGIGDVSAQLLFPTSKVNKG------------------------------------------------------YDYKRTAR----------------AVIYGSLIFSFIGDKWYKILNNKIYMRNRPQYHWSNMVLRVAVDQLAFAPLGLPFYFTCMS-IMEGRSFDVAKLKIKEQWWPTLLTNWAVWPLFQAINFSVVPLQHRLLAVNVVAIFWNTYLSYKNSKVMEKDKVPVHYPPVVE---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08743-1", "uniprot_id": "YO292_YEAST", "id": "Q08743-1", "name": "Vacuolar membrane protein YOR292C", "aln": "MPLQLFGRDQIVVHYDNGNMSNDDQNHQSVLGSWTRRAAAALRTLMNKRIQRITLTHWLLLVIWVTSLWKFTSHYRQLYANSAVFATLCTNILLFGISDILAQSIACFYSYHVDPIPQILN--------DTFHHVQNNRDVENGGGYESDELSIFNDFTSEHSSYTDNDDYPELDRPLATFKTDTFDFFRWGCFMFWGFFISFFQAPWYKFLN----FFYTEDPTVVQVFERVLSDQLLYSPISLYCFFMFSNYVMEGGDKDTLGKKIQRLYISTLGCNYLVWPMVQFINFLIMPRDFQAPFSSSVGVVWNCFLSMRNASK------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .. *: .: * *: * . . * : *: : :: ** * : :: . ::* . :. : : ** ::. : . .. * *. . . ", "identical_positions": 14, "similar_positions": 36, "identity": "4.06%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-283", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0G8-1", "uniprot_id": "A0A8I6A0G8_RAT", "id": "A0A8I6A0G8-1", "name": "Neurobeachin-like protein 2", "aln": "MAASERLYELWLLYYAQKDLGYLQQWLKAFVGVFEKTISLSSLEP------RRPEEAGAEVPLLPLDALHVLAEQLDQD--NLEQA-----------LLLLKLFIILCRNLENVEAGWGQVLVPRVLALLTGLMAELKGSPPSQEDRSTQLENVALHALLLCEGLFDPYQTWRRQHSGEAISSKEKSKYKFPPAALPCEFGAFFQESLQDAEHLPPTLLLR-LIHLFGAVLAGGKENGQMAVSSGSVQGLLG----VLRGWGRGPAQ------DPHKMQLALRALVGAVHVLHASRAPPRGPE---LRTLLEGYFHILNADWPASPSSS----PEEALVALRVSMLDAIPMMLACEDRPVLQATFLSNN--------CFEHLIRLIQNSKLYLQ-ARAPPE--GDSDLATRLLTEPDVQKVLDQDTDAIAVHVVRVLTCIMSGSPSAKEVFKERIGYQHLQEVLQSHGPPTHRLLQELLNMAVEGDHSMHPPPPIRNEQPVLVLTQWLPALPTAELRLFLAQRLWWLCDSCPASRATCVQAGLVSYLLETLNTG-TALGARCQEQLFALLQALGRVSLRPLELRRLLRPPPGLDSESCGTESQKAQHAGAIIRALSGMAR-HRGPARALRYFDLTPSMAGIMVPPVQRWPGPGFTFHAWLCLQSTEAAP--------------TSAPSRPLQRKQLYSFFTSSGSGFEAFFTAAGTLVVAVCTRKEYMTLSLPEVSFADSAWHSVAIVHVPGRRPFSQNLVNVFKDGHLVKTAPLRFPSLSEPFSSCCIGSAGHRTTTTTTG----LPVSSVS----TALSHT-HPSLTRSQSVPASTGLGWGPGLGAPPQEGSISSTLAGTQDTRWGSPTSLEGELGTVAIFHEALQASALRILCILGPNEPAPFKPEGELHELGAKLLLHYSPQACKNNICLDLSPGHGLDGRLTGHRVETWDVKDVVNCVGGMGALLPLLERVAVQPQEAEAGP---CETHDLVGPELTSGHNTQGLLLPLGKSSEERMERNAVAAFLLMLRNFLQGHTVNQESLVQCQGPAIIGALLRKVPSWAMDMNVLMSAQLLMEQVA---ADSSGPLLYLLYQHLLFNFHLWTLSDFAVRLGHIQYMSSIIREHRQKLRKKYGVQFILDALRTHYSPQRERPLAADDLRTVQTSLLGLVREFLVRNLSVDDMQV---VLSFLAAANEDCQVVGTLDLLLALLQGSPAQEPLAIFLLEPGNLEVLLTLLVRPKSTPLLSDRVCKILRRLQQNERLPERNRQRLRLHDCG-----LQGLVASLPEGIASPQLCQGLYKLFVGTVPQVVSPDCLNLSDLLAVVQLSLQADLSVRLDICRQLFHLIYGQPDVVRLLARQAGWQDVLTRLYVLEATATDSGPPRFVPELPTS---------------------------------------------------SELALSPPPTELPAESSDVFLPSESPCPDPDAFYHALSPFSMPFDLGLERASVDSGNTAGGS-------SSNGTITPAS-QPGTPSPLDGPRPFPTTQGRHSSSLSNVLEDGSLLEPTISGDDTSNT------SNPQQTPEEELCNLLTNVLFSVTWRGVEGSDEAAWRERGQVFSVLTQLGASAMLVRSPDCIKRSLLEMMLESALTDIKEAPPGGLANLSQQALWLLRLLQDFLCAEGHGNQELWSEKLFEGVCNLLDRLGAWPHLAN--SIADLREMAQIGLRLVLGYILLE-DPQLHAQAYVKLHTLLQTAVPTRREEACYVLSKLEAALSRALTASSSE---TEH--------SCAAMAASERCSWLVPLVRTLLDRAYGPLGLQWGLPSLPPTNGSPTFFEDFQAFCATPEWRHFIDKQVQPTMSKFEMDTYAKSHDLMSGFWNACYDTLMSSGQRLQRDRIQSRRAFQVCSPAWGTVPPHLHGWRQLVGQGREWVGETAASGIDLFLPPQELVLEPAQRRARLEGLRYASVLKQQAAQHSTALLHWGALWRQLSSPCGAWALRVPPTPHWKLSSAETYSRMRLKLVPNHHFDPHLEASALRDNLGEAPMTPTEEASLPLAVTKEAKISAPPEELLEDQLGEEELAVLETLMEAAELDEQREKLVLSAECQLVTVVAVVPGLLEVTTQHVYFYDGSTERVETEEGIGHDFRRPLAQLREVHLRRFNLRRSALELFFIDQSNYFLNFPHKVAGASASPPCQAPRPQLYPIPPHTQVRNQVYSLLLRLRPPTQGYLSSRSPQEMLRASGLTQKWVQREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLQDYVSPVLDLNNPAVFRDLSKPIGVVNPKHAQLVREKYESFEDPAGTIDKFHYGTHYSNAAGVMHYLIRVEPFTSLHVQLQSGRFDCSDRQFHSVAAAWQARLESPADVKELIPEFFYFPDFLENQNGFDLGCLQLTNEKVGDVVLPPWASSPEDFIQKHRRALESEYVSTHLHEWIDLIFGYKQRGPAAEEALNVFYYCTYEGAVDLDHVADERERKALEGIISNFGQTPCQLLKEPHPPRLSAEEAAIRLARLDTHSPSIFQNLDQLKAFFAEVVSEGVPLLLALVPHRQTHSFITQSASDMLVTVSASGLLGTHSWLPYDRNINNYFSFSKDPTMGNPKVQKLLSGPWAPGSGVRGQALAVAPDGKLLFSGGHWDGSLRVTLLSRGRLLSQLSRHLDVVTCLALDTCGIYLISGSRDTTCMVWRLLQ--QNGLSAG------------------------LAPKPVQVLYGHEAAVSCVAISTELDMAVSGSEDGTVIIHTVRRGQFVAALRPPGATLP-GPISHLALGSEGQIVVQSSACERPGAQVTYSLHLYSVNGRLRASLTLTEQPTALTVAEDFVLLGTAQCSLHILHLNKLRPAVPPLPMKVPVHSVSVTKERSHVLVGLEDGKLIVVGAGQPSEVRSSQFARKLWRSSRRISQVSSGETEYNPGEAR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZQA0-1", "uniprot_id": "NBEL2_MOUSE", "id": "Q6ZQA0-1", "name": "Neurobeachin-like protein 2", "aln": "MAASERLYELWLLYYAQKDLGYLQQWLKAFVGVFEKTISLSSLEP------RRPEEAGAEVPLLPLDALHALAEQLDQD--DLDQA-----------LLLLKLFIILCRNLENVEAGWGQVLVPRVLALLTVLMAELKGS--SQESHGTQLENVALHALLLCEGLFDPYQTWRRQLTGEVISSKEKSKYKFPPAALPCEFGAFFQENLQDAERLPPTLLLR-LIHLFGAILAGGKANGQMAVSAGSVQGLLG----VVRGWGRGPAQ------DPQQVPLALRALVGAVHVLHASRAPPRGPE---LRTLLEGYFHILNADWPTSPSSS----PEEALVTLRVSMLDAIPMMLACEDRPVLQATFLSNN--------CFEHLIRLIQNSKLYLQ-ARAPPE--GDSDLATWLLTEPDVQKVLDQDTDAIAVHVVRVLTCIMSGSPSAKEVFKERIGYQHLQEVLQSHGPPTHRLLQELLNMAVEGDHSMHPPPPIRNEQPVLVLMQWLPALPTAELRLFLAQRLWWLCDSCPASRTTCVQAGLVGYLLETLNTG-TALGARCQEQLLALLQALGRVSLRPLELRRLLRPPPGLDSESSGNESQKARHAGAVIRALSGMAR-HRGPARALRYFDLTPSMAGIMVPPVQRWPGAGFTFHAWLCLQSSEAVP--------------TSAPSRPLQRKQLYSFFTSSGSGFEAFFTAAGTLVVAVCTRKEYVTVNLPEVSFADSAWHCVAIVHVPGRRPFSQNLVNVFKDGHLVKTVPFRFPSLSEPFSSCCIGSAGHRTTTTTTG----LPASSVS----TALAHT-HPSLTRSQSVPASTGLGWGPGLGTPLQEGSVSSTLAGTQDTRWGSPTSLEGELGAVAIFHEALQPSALRVLCSLGPNEPAPFKPEGELHEFGTKLLLHYSPQACKNNICLDLSPGHGLDGRLTGHRVETWDVKDVVNCVGGMGVLLPLLERVAVQPQEAEAGP---CETHDLVGPELTSGRNTQGLLLPLGKSSEDRMERNAVAAFLLMLRNFLQNHTVNQESLVQCQGPAIIGALLRKVPSSAMDMNVLMSAQLLMEQAA---ADGGGPLLYLLYQHLLFNFHLWTLSDFAVRLGHIQYMSSMVREHRQKLRKKYGVQFLLDALRTHYSPQRERPLAADDLRTVQTSLLGLVREFLVRNFSVEDMQV---VLNFLAATGDDGQVVGTLELLLTLLQGSPVQDPLAAFLLELGNLEVLLALLVRPKSTPLLTDRVCKILRRLQQNERLPERNRQRIRLHDCG-----LQGLVASLSEESISPQLCQGLYKLFVG-------TDCLNLSDLLAVVQLSLQADLSVRLDICRQLFYLIYGQPDVVRLLARQAGWQDVLTRLYVLEA-ATDSSPPRFLPELPIS---------------------------------------------------SELALSPPPTELPADSSDVFLPSESPCPDQDAFYQALSPFSTPFDLGLERASIGSGNTAGGG-------SSNGTVTPAS-QPGTPSPLDGPRPFPTAQGRHSSSLSNVLEDGSLLEPNISGDDTSNT------SNPQQTPEEELCNLLTNVLFSVTWRGVEGSAEAAWRERGQVFSVLTQLGASATLVRPPDCIKRSLLEMMLESALTDIKEAPPGGLANLSQQALWLLRLLQDFLCAEGHGNQELWSEKLFEGVCNLLDRLGAWPHLAN--STADLREMAQIGLRLVLGYILLE-DPQLHAQAYVKLHTLLQTAVPTRREEACYVLSKLEAALSRALTTSSSE---TEH--------ASTAVAASERCSWLVPLVRTLLDRAYGPLGLQWGLPSLPPTNGSPTFFEDFQAFCATAEWRHFIDKQVQPTMSKFEMDTYAKSHDLMSGFWNACYDTLMSSGQRHQRDRIQSRRAFK------------------------------------------ELVLEPAQRRARVEGLRYASVLKQQAAQHSTALLHWGALWRQLSSPCGAWALRIPPAPHWKLSSAETYSRMRLKLVPNHHFDPHLEASALRDNLGEAPMTPTEETSLPLAVTKEAKISAPPEELPEEQLGEEDLAALESLMEAAELDEKREKLVLSAECQLVTVVAVVPGLLEITTQHVYFYDGSTERVETEEGIGHDFRRPLAQLREVHLRRFNLRRSALELFFIDQSNYFLNFPHKVAASSASSPCQAPRPQLYPIPSHTQLRNQVYSLLLRLRPPTQGYLSSRSPLEMLRASGLTQKWVQREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLQDYVSPVLDLSNPAVFRDLSKPIGVVNPKHAQLVREKYESFEDPAGTIDKFHYGTHYSNAAGVMHYLIRVEPFTSLHVQLQSGRFDCSDRQFHSVAAAWQARLESPADVKELIPEFFYFPDFLENQNGFDLGCLQLTNEKVGDVVLPPWAGSPEDFIQKHRQALESEYVSTHLHEWIDLIFGYKQRGPAAEEALNVFYYCTYEGAVDLDHVADERERKALEGIISNFGQTPCQLLKEPHPPRLSAEEAANRLARLDTNSPSIFQNLNQLKAFFAEVVSEAVPLVLALVPHRQSHSFITQSSSDMLVTVSASGLLGTHTWLPYDRNINNYFTFSKDPTMGSPKVQKLLSGPWVSDSGVSAQALAVAPDGKLLFSGGHWDGSLRVTSLPRGRLLNQLSRHLDIVTCLALDTCGIYLISGSRDTTCMVWRLLQ--QSGLSAG------------------------LAPKPVQVLYGHVAAVSCVAISTELDMAVSGSEDGTVIIHTVRRGQFVAALRPPGATLP-GPISHLALGAEGQIVVQSSACERPGAQVTYSLHLYSVNGRLRASVTLTEQPTALTVAEDFVLLGTAQCSLHILHLNKLRPAVPPLPMKVPVHSVSVTKERSHVLVGLEDGKLIVVGAGQPSEVRSSQFARRLWRSSRRISQVSSGETEYNPGEAR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZNJ1-1", "uniprot_id": "NBEL2_HUMAN", "id": "Q6ZNJ1-1", "name": "Neurobeachin-like protein 2", "aln": "MAASERLYELWLLYYAQKDLGYLQQWLKAFVGAFKKSISLSSLEP------RRPEEAGAEVPLLPLDELHVLAEQLHQA--DLEQA-----------LLLLKLFIILCRNLENIEAGRGQVLVPRVLALLTKLVAELKGCP-PPQGRGTQLENVALHALLLCEGLFDPYQTWRRQRSGEVISSKEKSKYKFPPAALPQEFSAFFQESLQNADHLPPILLLR-LIHLFCAVLAGGKENGQMAVSDGSVKGLLS----VVRGWSRGPAP------DPCLVPLALEALVGAVHVLHASRAPPRGPE---LRALLESYFHVLNADWPAGLSSG----PEEALVTLRVSMLDAIPMMLACEDRPVLQATFLSNN--------CFEHLTRLIQNSKLYLQ-SRAPPE--GDSDLATRLLTEPDVQKVLDQDTDAIAVHVVRVLTCIMSDSPSAKEVFKERIGYPHLQEVLQSHGPPTHRLLQELLNMAVEGDHSMCPPPPIRNEQPVLVLAQWLPSLPTAELRLFLAQRLRWLCDSCPASRATCVQAGLVGCLLETLSTG-LALEARCQEQLLALLQALGRVSIRPMELRHLLRPRPGLDSEPGGAEAGKARHAGAVIRTLSGMAR-HQGPARALRYFDLTPSMAGIMVPPVQRWPGPGFTFHAWLCLHPMDTAP--------------TPAPTRPLQRKQLYSFFTSSGSGFEAFFTAAGTLVVAVCTRKEYLTMSLPEVSFADSAWHCVAIVHVPGRRPFSQNLVHVYKDGHLVKTAPLRCPSLSEPFSSCCIGSAGYRTTTTTTG----LPTPPVP----ATLAYT-HPALTRSQSVPASTGLGWGSGLVAPLQEGSIDSTLAGTQDTRWGSPTSLEGELGAVAIFHEALQATALRTLCTLGPNETAPFKPEGELHELSTRLLLHYSPQACKNNICLDLSPSHGLDGRLTGHRVETWDVKDVVNCVGGMGALLPLLERVAAQPKEAEAGP---AETHDLVGPELTSGHNTQGLVLPLGKSSEERMERNAVAAFLLMLRNFLQGHMVNQESLVQCQGPAIIGALLRKVPSWAMDMNVLMSAQLLMEQVA---AEGSGPLLYLLYQHLLFNFHLWTLSDFAVRLGHIQYMSSIVREHRQKLRKKYGVQFILDALRTHYSPQRERPLAADDLRTVQTSLLGLAREFLVRSLSADDVQVTQTMLSFLAATGDDGQAVGALDLLLALLHGSLVQESLAVFLLEPGNLEVLLALLVRPGSLPLLPDRVCKILRRLQQNERLPERSRQRLRLRECG-----LQGLVACLPEGTVSPQLCQGLYKLFLG-------ADCLNLSDLLAVVQLSLQADLSVRLDICRQLFHLIYGQPDVVRLLARQAGWQDVLTRLYVLEA-ATAGSPPPSSPESPTS---------------------------------------------------PKPAPPKPPTESPAEPSDVFLPSEAPCPDPDGFYHALSPFCTPFDLGLERSSVGSGNTAGGG-------GSSGTLTPAS-QPGTPSPLDGPRPFPAAPGRHSSSLSNVLEDGSLPEPTISGDDTSNT------SNPQQTSEEELCNLLTNVLFSVTWRGVEGSDEAAWRERGQVFSVLTQLGASATLVRPPDCIKRSLLEMMLESALTDIKEAPVGVLASLTQQALWLLRLLQDFLCAEGHGNQELWSEKLFEGVCSLLDRLGAWPHLAN--GTADLREMAQIGLRLVLGYILLE-DPQLHAQAYVRLHMLLQTAVPARREEACYVLSKLEAALGRVLNTSSLE---SATDEAGSPLAAAAAAAAAERCSWLVPLVRTLLDRAYEPLGLQWGLPSLPPTNGSPTFFEDFQAFCATPEWRHFIDKQVQPTMSQFEMDTYAKSHDLMSGFWNACYDMLMSSGQRRQWERAQSRRAFQ------------------------------------------ELVLEPAQRRARLEGLRYTAVLKQQATQHSMALLHWGALWRQLASPCGAWALRDTPIPRWKLSSAETYSRMRLKLVPNHHFDPHLEASALRDNLGEVPLTPTEEASLPLAVTKEAKVSTPPELLQEDQLGEDELAELETPMEAAELDEQREKLVLSAECQLVTVVAVVPGLLEVTTQNVYFYDGSTERVETEEGIGYDFRRPLAQLREVHLRRFNLRRSALELFFIDQANYFLNFPCKVGTTPVSSPSQTPRPQPGPIPPHTQVRNQVYSWLLRLRPPSQGYLSSRSPQEMLRASGLTQKWVQREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLQDYVSPTLDLSNPAVFRDLSKPIGVVNPKHAQLVREKYESFEDPAGTIDKFHYGTHYSNAAGVMHYLIRVEPFTSLHVQLQSGRFDCSDRQFHSVAAAWQARLESPADVKELIPEFFYFPDFLENQNGFDLGCLQLTNEKVGDVVLPPWASSPEDFIQQHRQALESEYVSAHLHEWIDLIFGYKQRGPAAEEALNVFYYCTYEGAVDLDHVTDERERKALEGIISNFGQTPCQLLKEPHPTRLSAEEAAHRLARLDTNSPSIFQHLDELKAFFAEVVSDGVPLVLALVPHRQPHSFITQGSPDLLVTVSASGLLGTHSWLPYDRNISNYFSFSKDPTMGSHKTQRLLSGPWVPGSGVSGQALAVAPDGKLLFSGGHWDGSLRVTALPRGKLLSQLSCHLDVVTCLALDTCGIYLISGSRDTTCMVWRLLH--QGGLSVG------------------------LAPKPVQVLYGHGAAVSCVAISTELDMAVSGSEDGTVIIHTVRRGQFVAALRPLGATFP-GPIFHLALGSEGQIVVQSSAWERPGAQVTYSLHLYSVNGKLRASLPLAEQPTALTVTEDFVLLGTAQCALHILQLNTLLPAAPPLPMKVAIRSVAVTKERSHVLVGLEDGKLIVVVAGQPSEVRSSQFARKLWRSSRRISQVSSGETEYNPTEAR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FAW3-1", "uniprot_id": "NBEL2_DANRE", "id": "E7FAW3-1", "name": "Neurobeachin-like protein 2", "aln": "MASKERLYELWMLYYTKKDVVYLQQWLEAFVASFEKVIDVHSIEP------RRLEEWSADVPLLPKEVLVFLSTQLWHS--ALHMSGQDQSITAPHPLLLIKFFIIICRNMENIDSEKTPGFVFETIKLLNFCLAQLKKQP----DDQSTLQAVVQHGLLLCENLFDPYQTWRRRQAGEEVSMLERSKYKFSPLVLPEELPMLFHEYLQDSELIPEPLVVR-LVHLQGAVISGCKRNGLLSITPQAVKDLMS----VLRSWCLCPASSPQQPRDPQLLRMALRCLTVMIHLLHSSSVNERQVE---IRSALDDYFQLLNWNRPPDSQQGDMHAWEDNLITLLEHMLNAIPEILQCSDRPVLQAIFLNNN--------CFEHILRLIQNSKLYQS-NRFKLECEGQCDLTTRLLTESEVEQVWEKGSDCITVHAIRVLTAIMSNSPSAKEVFKERIGYSQLFDVLKSQGQPTKRLLQELMNMAVEGEHSQAMQLGISNEQPLLLLLQWLPDLGSRSLQLLVSQWLAAVCRGTLSCRTVSVEAGLVGSLLEVLSEPPERLDRQCADSLLGLLQDLGSLSLRPCELKSLLK---LLRTEPG---APPHPYCGRVVRVLSAMAARGEGGCSALQYFDLTPPMAGIMVPAIQRWPGSAFAFHAWLCLNTDFPPPQHHYSESHLTNMDNTVRMAKGPRRKQLYSFFTASGTGFEAFFTTEEVLVVAVCTKKEYMAVSLPEHPFNDCAWHSVAIVHVPGRRPFGQNVVTVYVDGVQCKTAPLRFPSLNEPFTSCCIGSAGHRTTTTTMTTSPTLPNPPHSPSEMAFAAHTGPPTLLRSQSFPASFAAAAG-GRPGGNRESPVHTIQAGLQDTAWGSPSSLGGLLATAFICHEALQPAQARALFTAGPNNVSLFKADGEPSEVNSKLVLYYTPKAFKSQICLDLSPNHLYDGRLTGHRVVNWDVKDVLSSVGGMGALLPLLEQVCLLDQRETVG----QETSDLLGPELTSSRGPAGMLLPLGKSSEGRLEKNSVAAFLLMIKNMLRNHPANQESLLQCHGPAIIGAMLGKVPSSMMDMSVLMACQFLLKQVS---NEGNNALLSQLYQYLLFDFRIWSRSHFAVCLGHVQYLTTVINEGKLKTRRKYGVQYILDSIRTHYSVEKDGSPLSDERQTVQISLFSLLKDLLK-SPTAEELHS---VLAYAAIVQDEQQVISVLDVLHTVLKSSPPPREQVVTVLLDRRVEQLYYLLLKTNYGDEARERLFRVMYKVLKSERVHDRNKQLIKLKDSG-----YLGLVCSFGDVPITMTTVRCLYEQVLAT------DPTPSFKDLLAVVYLSHRADLSARLEIVRKLFCLIHSNEEYVKQLAHQSGWQDVLTKLYVKESYESRVRSQSNSLSSPTSSLDPVLSRPVFRRDDSVTEDVRQNVYITLAARHEEEYEEEEGETQDASEGFSDLSQSPPSTGQLKNDSLHFKPFDSGDQSSHSSTLSNTVDFPPSRLQEEDEAVYQPLSPFGSPFELELNHQKGPQTPVGSQPETPSPLEHNKTFLGMRPRKSSSLSNVLDDTSYSTEPPT-DTISNT------SNPQ-APEEELCNLLTNIVFSVLWIGTEGSEDVIWRERGQVFSVLTKLGSSCQLVRPPDDIKRSLLEMMLESSLSDLRDSQ-GVSLPHVPSLLRLLRLLQDFLFAEGTCNHTLWSEKIFEGVVNLLDRLKAWHTTPGSAGSAELKEMSLIGLRIITGYIQQQQNPQVCEMACLKLHSLLQTVLCLSWEEVCFLLGRLGAPLCPANSASDTS---AEG-----------------LPSPLVPIVRALLDQHADHTTLQEKLPNLPATNGSPSFAQDLQIYCSTAEWQQFYQNHVEPTMQQYELDTFGKSHDLMSNFWNSCFDDLMSTGQRRDKERSDSKAKFQ------------------------------------------EVIVDPYLKRVRTENSRYHSVQKMINGQQTVVWRHWRSLRRLLSSDRGAWPLRVQPEVKWKLSSAETYSKMRLKLVPNYSFDSHSDASALRDNMGADSPRSSTEP-LPLAVAREAKVSD----MDDDKLEDEDIVFLEEAEEAEEES-QKEKLVLSEDCELITIVAVVPGRLEVTTHHLYFYDGSSEKEETEEGIGFDFKRPLSQLREVHLRRYNLRRSALELFFIDQSHYFINFR-------------------------KGVRNKVYSRILGLRPPNLFYFGSRSPQELLKASNLTHRWVCREISNFEYLMQLNTIAGRTYNDLSQYPVFPWVLCDYTSAELDLDDPAVFRDLSKPIGVVNPRHAQNVREKYESFEDPTGTIDKFHYGTHYSNAAGVMHYMIRTEPFTSLHIQLQSGKFDCADRQFHSIAAAWQARMESPADVKELIPEFFYFPEFLENMNGFDLGCLQISQEKVNNVLLPPWASSREDFIRKHRKALESEHVSAHLHEWIDLIFGYKQRGPEAVEALNVFYYCTYEGAVDLDAIANETERKALEGIISNFGQTPCQLLKEPHPPRMSAENAFRRAARLDILPPNLFDQLSKLRS-FKEVVSDGLALVQAVVPRNQTRSFIIPGS-DILVTVSANGMIGTHSWLPYDKNIANYFTFTRDPSVSNPKTQRFLSGPFSPGVEMGSQVLVVSSDGRLLFSGGHWDCSLRVTMLGKAKLVGRICRHIDVVTCLALDLCGIYLISGSRDTTCMVWQVLQ--QGGFSSG------------------------LSPRPIQVLCGHDQEVTCVAISTELDMAISGSKDGTVIVHSVRRGQYLWTLRPPCENCVSAPVAQLEVGMEGHIVMQTVLEGRSAGKERYALHVYSVNGTLLASETLDEKISALYLVPDYLIVGTQQGNLHIRDLYSLNLAVAPLALKVPVRCVSVTKESSHILVGLEDGKLIVVGAGKPEEVRSGQFSRRLWGSTRRISQVSSGETEYNPVEAPAK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9MRV7-1", "uniprot_id": "M9MRV7_DROME", "id": "M9MRV7-1", "name": "Neurobeachin-like protein 1", "aln": "MDNKKDIYNLWVQYTTKNDETHFRQFVARFVAIWRSQLQLDFQAENCPMWHEVQPDSGPHLGRLPDELLPAIGKFIIVARDVCETEGKLEEQAIEEVAILVDCLVIVCRHFDNILSIIKYEYKPNLIAILSRVFKQQMELP----QSVPAISHLFSSFSAFLEVMYDPYLTWRSFVRG---QSADYSRLSYKPHSVHVEIVPFIYDCFQEEKLIRYAEIGESLLNILGAVICGSQLQLKVQKSLNSTSTLTNRNTNALTTSSLAPCSG-DGLLDCDNLRNGMKAICPATVSITMSILRQWESANNLRRVALQCYALMVIVLQKSSPEER-----QIDLVTLVQLYCDALQELLATKHFDSGDANFDITSDADQDVAIDMAALSSTVAAVKFFVTGDAGVSEAVSDSNLLELLTNLPKLIKPWHISHSSSLCSTMEALAILARHSPQSASQLRQGERIERLFTSLQEYGSPTVELLDTCFMLGYDESEHFLLLP-----EVMLRLLNWVPTLQER-EQLHVTSLVLKGCTDNYRTKTVACGSHIIKAVCGCLLTA-ESLAENCVQNLIKLIEELSKLSIVPAELKCIFS----LLRQGTKFPQFKQLQQTLVVIALQSLRG----SNSCAEFFSIEQPTDGILVPDIRNWTISGSYGFIFHILVRFNQLK------------------EQSNSRRMLLTLQTASGSGFEVFVQPNGNVVVAALTRREYLTSSTATKTLMDGQWHYLTVAITPPKRPFSYSQINIYVDFVQKLSATLKVQAVNEPFTVCSIGAVVAPPQPGEVAKTGNMPRSSSQESGSSGYKGMLPSLLERTLSANVSNYFTLPMRTQTAFDPN-VKNFPIGMQDTVFGEQTCLNGHLGGVLLADP---TTSLKTIFDAGANFSSIFSQDNDLLELNSRFVFCYAPGAIWHGTCQDLIPGGKYPGRINAQHCKIVKIQETINSIGGISAILPMLHRLITLDQTTDISIGSVSEESLSCAPTPSAEEFTDWEMLSSNSYTEWKMLQHPLASFLCLLRYLTHEHETNQEQLLSSECLAIVGTMLQRCPPSLFDVNALMATHLLMESLQGHKAEAGGQLLDALYAHIVFDFAIWSRLQFQITLGHAQYLSAMIKNDRKFFRKRYGVQFVLDVVRQYYSTP--DSISDDDAKTIRATLFGIIKFYLQKDVNIKEVNS---MITFLASVRQDVVLVEFLEMMTFYVRGKNCKDQMVLLLHEPQSANLLYNFFVDKSYSNEIQEAAIRFISGLLATSRVHQKYKQVLRLYDQTTEQSMFPGFFSFITPLSLSSTILFHLVDEMLG--------LQPDYAGLIFLVYHVSSCDLPVKLEIAKRLLQTTFVKQQSTVAMAKQTGWQESIARLLIRKPITSSPPDEEKRRSFGIN----------------------------------LDVLLEDNSNFLAQADLITFSEQEIGLAQLQQQQQEELSDSGLILNEIQASVTEAATVIESEIKELAESVSGAVVENANSLFSVIRQTTHDLQDTFESLTQGSSTDTADGSQTPSIQREESLSSDTSSQSPHGPPKKSDSLESTSAFDFVADGDVDTEEQLVYLVSNTLFNIFWRGIPNDHPQCWQERGQVLGCINLLALNNELITSHLSLRLRILEMAVQASLFDLSEHGSQTLVNQENASHILRMVYELVVLGSNEDESKKCSTKLLDGVLALLDALMIFQQGSS----DDWSDMIRLCLGLLLKCSHHP-NPGIVAMATAKLHAILQSRSTEDPAELSYLLYSINRALDNAIEVGNPEEYS-----------------------FLMPVMKALLEKCRVAFNLDSTLPDLPSTSSGPVFFNDFQMYSTSKKWRNFIERMVKPLYDRYQRDIELHLWEPINRFWAECYEACKAASKQRATNQAENRRLFQ------------------------------------------QKIYMPWKVRQVEEMQRLQAAALQHKTIDSHIRKRWKTAKRFLYGPRGPWYTGEVDEEFWKLSQHENVARMRLKLEPQLYPNKHENAANLRDNA-----TSAYDTKEISEFDSTIKNAVVRDFLADDESSQLEEELRQLIDTQAQQDVALEKLVMSQDCELITLMTKVKGRIEVNQSVFTFVDLSPP---TEDGSKYDFRFSTNKIREVHLRKYNLRRSALEIFLVDQTSYFLNFT-------------------------TKTRNKVFTKIVGLPLPNILYGSGRSPAELLRASGLTQRWINREISNFEYLMYLNTIAGRSYNDLSQYPVFPWILADYTSDVLDLTDPKSFRDLSKPIGCINPKNEAEVRGKYDSFEDPSGAIPKFHYGTHYSNSAGVLHYLLRVEPFTSLHIDLQSGRFDVADRQFHSIPQTWKLLMDNPNDVKELIPEFFYFPEFLKNMNKFDLGHLQITKEKVDDVILPAWATTPEEFIAIHRRALESEYVSQHLHHWIDLIFGYKQKGPKAAEALNVFYYCSYEGAVDLDKITNPVEREAVEGMINNFGQVPSQLLREPHPRRLTQDETALKLVRAELRRPDLTQFLDKVVQYYCELSTPKDPIVYLSPPRSPPRSFLQLSP-DVLVSISKSTILGCNSWLSFDKDQG--FLLEIDATTANLKNRKRIFGPFHSSQQPHSQLFAVSTDGKLLYAGGIWDNSLRVYNLNKGKAVASVTRHLDIITCIALDNCGSYLVTGSRDCTCIVWSIQTNQQGGGSTNNIPVHALTGQSHLQAITQLNTQNSYSPKPLTVLYGHDDAISSVAIYTELDLVVSGSLDGTVNVYTLQEGQFVRTLKPIGCTESCVQISFVTLSYHGHIAFS------ALDDTSHSVHVYSINGCSLGSKYVSGRVTGLASASDYLVVADDAGDITMSRLHGLKPVFD-IPLHVPIQTVVVTPGNTHILAPLRDGRLAVIAVQLPSGGNKKHSVLNV-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .: :*:**: * :::* :::*:: **. :.. :.: . : ...: ** : * :. : . :*:. ::*:**:::*: : . : :*. . : . :. : : * ::*** *** * . : *: .: * : *: :: : :*: . : : . *::: *::.* : : : : :.. * . .: *. * : .:..: : * * *: * :: .. .. : *::* :*: :* .. :* * .. : : : *:: * .:.:* * . ..: : . . .. .:..*: : **.: . ::: :* *:. * ** .**: : :. : .. : :* * :*:* * :* ::. : * . ::.. : :: : * * .* :.*: *:: *. :*: * **: :: * : :: .*..: . .:*.: . **:** ::.*. .. . : * : *: * :: *:**:***.*. . :***. *::**:: . . .: * ** :::. .* :***. . : :: * :..:: ::.***: *.**:. . . :* .. : . * *: * .* . : . * *** :*. :.* * *. . : . .: : : *.* : *. :.: *..::::: *:* * * ** *. **:..:: .:::.:..:**:..:**:*.:: : . * .* :: . . :*. .. :* :: ::.:*:** ::: : : * .***.*:... **:*::* : *. :*:..**: ::*::. :... ** ** :::*:* :*: .* : *** **:::::.: : *::****::** :* :** . *: :*:: :*:.: : * . . .::: :: : * . :: : *::: ::.. . : : * ::: : :.: : ..*: :: :* ::* : *:.. : : * . .:. . .*: :* .**..:*:* ::*: . : : . :*:*:***: :::* : :. : . . : : . . .. . : : : :: .. . . . *. : ::..***. .. * . * ..* :: : .**:* *::* :*.: * * .. *:*****:. :. *. . *: . :: :*** ::::* *: : * : : .: ... : * *:::** *** * : .. : :* : * :: :* : * :** :**: * .::* : .* . ... . *:*::::**:: *: **.**.*...* * :*:* :.:: :*::* :. *:* .::: * : : :. ** *:: ::.:: :: :.: *: : : * * * * :. .: :* : * * . *.* ****. *. ::***** *: : * :*: **** .: :. . * : : ::: : : : : . ****:* :*:*:*::: * * :*:. . * * *. **:* .**: . ::******::********:*::**: **:** . **:*:: :: * *. * ..*** *:*:**.**::*: ********** *******:************:* **.* *** :* ********* :**:: ** **:*****:*:* **********:***:**::*.*******::****:** :******:. :*: ::.* *************:**:* * **** **:::***.:*:**.** : *:** **:*****:** ***.**********:** * *********:******** ::: **:*:**:*.****.*.***:**** *:: ::: : .* : *.: : *.:: : *: : .:: *: .:**: .. *:**::* . ::* ::**.:*:: * : *.: .. * :: : **: .. .* :.*:.**:**::** ** **** * :.: : : *:*::**:*** ** **::**** **:** : *.* * . :*:*: ** ** ::.*** ****:.:*** **** :::::.**:: :*:* . : : :. .*:*... . . :::*:**:** .* : : :.* . *::::. : : * * . :.::*.:: * ** :*:*. *.**:* *: . *. .. : .: ", "identical_positions": 665, "similar_positions": 874, "identity": "22.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-285", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AY88-1", "uniprot_id": "KDF1_RAT", "id": "Q6AY88-1", "name": "Keratinocyte differentiation factor 1", "aln": "MPRPGQPRPSSGPPRLGPWERPTELCLETNDERSQPPPGRRTRRPDPKDPGHHGPESITFISGSAEPANEPPTCCLLWRPWGWDWCRAAFCFRRCRDCLQRCGACVRSCSPCLSAGDPIEGSSEAAWAKEHNGVPPSPDRAPPSRRDGQKLKTSMGSSFSYPDVKLKGIPVYPYRHATSPVPDADSCCKEPLADPPPTRHSLPSTFTSSPRGSEEYYSFHESDLDLPEMGSGSMSSREIDVLIFKKLTELFSVHQIDELAKCTSDTVFLEKTSKISDLISSITQDYHLDEQDAEGRLVRGIIRISTRKSRSRPQTSEGRSARSTAP-AAAPDSGHETMVGSGLSQDELTVQISQETTADAIARKLRPYGAPGYPASQDSSFQGTDTDSSGAPLLQVYC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A9F4-1", "uniprot_id": "KDF1_MOUSE", "id": "A2A9F4-1", "name": "Keratinocyte differentiation factor 1", "aln": "MPRPGQPRPSSGPPRLGPWERPSELCLETNDERSQPPPGRRTRRPDPKDPGHHGPESITFISGSAEPANEPPTCCLLWRPWGWDWCRAAFCFRRCRDCLQRCGACVRGCSPCLSAGDPIEGSAEAAWAKEHNGVPPSPDRAPPSRRDGQRLKTSMGSSFSYPDVKLKGIPVYPYRHATSPVPDVDSCCKEPLAEPPPTRHSLPSTFTNSPRGSEEYYSFHESDLDLPEMGSGSMSSREIDVLIFKKLTELFSVHQIDELAKCTSDTVFLEKTSKISDLISSITQDYHLDEQDAEGRLVRGIIRISTRKSRSRPQTSEGRSARSTAP-AAAPDSGHETMLGSGLSQDELTVQISQETTADAIARKLRPYGAPGYPASQDSSFQGTDTDSSGAPLLQVYC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NAX2-1", "uniprot_id": "KDF1_HUMAN", "id": "Q8NAX2-1", "name": "Keratinocyte differentiation factor 1", "aln": "MPRPGHPRPASGPPRLGPWERPTELCLETYDKPPQPPPSRRTRRPDPKDPGHHGPESITFISGSAEPALESPTCCLLWRPWVWEWCRAAFCFRRCRDCLQRCGACVRGCSPCLSTEDSTEGTAEANWAKEHNGVPPSPDRAPPSRRDGQRLKSTMGSSFSYPDVKLKGIPVYPYPRATSPAPDADSCCKEPLADPPPMRHSLPSTFASSPRGSEEYYSFHESDLDLPEMGSGSMSSREIDVLIFKKLTELFSVHQIDELAKCTSDTVFLEKTSKISDLISSITQDYHLDEQDAEGRLVRGIIRISTRKSRARPQTSEGRSTRAAAPTAAAPDSGHETMVGSGLSQDELTVQISQETTADAIARKLRPYGAPGYPASHDSSFQGTDTDSSGAPLLQVYC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EZS2-1", "uniprot_id": "E7EZS2_DANRE", "id": "E7EZS2-1", "name": "", "aln": "--MENNPSWTSGPIEEGPYQ---ERSVDPVEIEIQSYGVRHKVNKDANG-NTTGPETVSFLPAKEEPASG---SCMCGPCASVGSCRKLFCSVLTCGLYRIC-----QRLPCLVSNESTAVTAQTEIQPISSQVQEG----------------------FYPDIRIAGVKVDP-----SVIEDVDG-------------------FDSVSPSTFEMNSLNVSGILEDDLVNGNK-MEDVDQLITQKLMEVFSEFEINELAKCTTDSMFLRRSREISQLISDIVEEHKMEEKEAECRLVREIIRISTRKSRKRPQIKQPELQRDSGN--DTWNSKGISQKSSFNSMSGQNLQISMERSDDIEARKFRNNSNQSFSRSFQETGVPITSDTP-LLYSRIQA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:* :*** . **:: * .::. : *. *:. . *.:. . ***:::*:... *** .*: ** ** . : * *** : :. :::: . * . ***::: *: * * * *.*. * . . .: * *:: *.: :: .*. .::* ** :** *:** .:*:******:*::**.:: :**:***.*.::::::*::** **** ********** *** .: . * :. : :* : .* * . .:*** * : * ***:* . .:. * :.: :*:. :: .", "identical_positions": 100, "similar_positions": 110, "identity": "25.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NBN7-1", "uniprot_id": "RDH13_HUMAN", "id": "Q8NBN7-1", "name": "Retinol dehydrogenase 13", "aln": "--------------MSRYLLPLSALGTVAGAAVLLKDYVTGGACPSKATIPGKTVIVTGANTGIGKQTALELARRGGNIILACR-DMEKCEAAAKDIRGETLNHHVNARHLDLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFDD-LNWQTRK--YNTKAAYCQSKLAIVLFTKELSRRLQGSGVTVNALHPGVAR-TELGRHTG--IHGSTFSSTTLGPIFWLLVKSPELAAQPSTYLAVAEELADV--SGKYFDGLKQKAPA---PEAEDEEVARRLWAES-ARLVGLEAPS---VREQPLPR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CEE7-1", "uniprot_id": "RDH13_MOUSE", "id": "Q8CEE7-1", "name": "Retinol dehydrogenase 13", "aln": "--------------MSRFLLPVSVVGTVIGGTVLLKDYVAGGACPSKATIPGKTVIVTGANTGIGKQTALELAKRGGNVILACR-DMEKCEVAAKDIRGETLNPRVRAERLDLASLKSIREFARKVIKEEERVDILVNNAAVMRCPHWTTEDGFEMQFGVNYLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFED-LNWQMKK--YDTKAAYCQSKLAVVLFTKELSHRLQGSGVTVNALHPGVAR-TELGRHTG--MHNSAFSGFMLGPFFWLLFKSPQLAAQPSTYLAVAEELENV--SGKYFDGLREKAPS---PEAEDEEVARRLWTES-ARLVGLAMAHGSPGRGHAIPR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8N7TEZ4-1", "uniprot_id": "A0A8N7TEZ4_DANRE", "id": "A0A8N7TEZ4-1", "name": "", "aln": "MLFTSACEMKDPGTSSDGVNYGAVLALLVISFVLLRKWIAGGVCKSHARLDGKTVVITGANTGIGRETAKDMAYRGARVVMACR-DLIRAEDAAEYIRRCTGNGNVVIRHLNLASLYSVREFAKEFIATEERLDILINNAGVMMCPKCVTEDRFETQLAVNHLGHFLLTNLLLEMLKRSSPSRVVNVSSIAHVGGKIEFDD-LFFDKRP--YSPLVSYKQSKLANVLFSRELARRMKGTGVSSYCLHPGVIR-TDLSRHIL--SWFPMLKTILYLPS-MLLMKTPWQGAQTTIYCAVTEGLESK--SGSYFSDCAEKDPA---PEGKDDLVARRLWEES-VRLVGLNDTLN----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08651-1", "uniprot_id": "ENV9_YEAST", "id": "Q08651-1", "name": "Probable oxidoreductase ENV9", "aln": "------------MLDPRILPYYDPAVERKIAVVTGGNTGIGWYTVLHLYLHGFVVYICGRNS---HKISKAIQEILAEAKKRCHEDDDGSSPGAGPGPSIQRLGSLHYIHLDLTDLKCVERAALKILKLEDHIDVLVNNAGIMAVPLEMTKDGFEVQLQTNYISHFIFTMRLLPLLRHCR-GRIISLSSIGHHLEFMYWKLSKTWDYKPNMLFTWFRYAMSKTALIQCTKMLAIKYP--DVLCLSVHPGLVMNTNLFSYWTRLPIVGIFFWLLFQVVGFFFGVSNEQGSLASLKCALDPNLSVEKDNGKYFTTGGKESKSSYVSNNVDEAASTWIWTVHQLRDRGFDI-------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . * . * : : * .* : * *: :: : : .. *: * .. .* : :*:*:.* .:.. * :.: *:::*:*:***.:* * *:* ** *: .*::.**::* ** *: . .*::.:**:.* : :. :: : . * ** * : :: *: : .* .:***: *:* : : :: : .: .: *: * .*.** :: : .: *: .: :* * *: ", "identical_positions": 57, "similar_positions": 94, "identity": "15.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-30", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97573-1", "uniprot_id": "SHIP1_RAT", "id": "P97573-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1", "aln": "MPAMVPGWNHGNITRSKAEELLSRAGKDGSFLVRASESIPRAYALCVLFRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIEFYKKENMGLVTHLQFPVPLEEEDAIDEPEED-TESVMSPPELPPRNIPVSGGPCEAKDLPLPTENPRAPEVTRLSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLMLDSDFLKTGSSNLPHLKKLTSLLCKELHGEVIRTLPSLESLQRLFDQQLSPGL-RPRPQVPGEANPITMVAKLSQLTSLLSSIEDKVKALLHE--GSESTNRRSLIPPVTFEVKSESLGIPQKMHLKVDVESGKLIIKKSRDGSEDKFYSHKKILQLIKSQKFLNKLVILVETEKEKILRKEYVFSDSKKREGFCQLLQQMKNKHSEQSEPDMITIFIGTWNMGNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLEILRHSLQEVTSMTFKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLNYRVELPTWEAEAIIQKIKQQQYSDLLAHDQLLLERKEQEVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKNGPGAVDSQGQIEFLACYATLKTKSQTKFYLELHSSCLESFVKSQEGENEEGDEGELVVRFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALR-LETTESQLPIYTPLTHHGEMTGHFRGEIKLQTSEGKMREKLYDFVKTERDESSGMKCLKNLTSHDPMRQWEPAGRVPACGISSLNEIINPNYIGMGPFG--QPLHGKSTLSPDQQLTAWSYDQLPKDSSLGPGRGEGPPTPPSQPPLSPKKFSSSTANRGSCPRVQETRPGDLGK--VEALPQEDLPLTKPEMFENPLYGSVSPFPKLVPRKEQESPKMMRKEPPPCPDPGVSSPSIMLPKAQEVENVKGTSKQAPVPVFGPTPRIRSFTCSSSAEGRMPSGDKSQGKPKAPASSQAPVPVKRPVKPSRSEMSQQTTPIPAPRPPLPVKS-PAVLQLQHSKGRDYRDNTELP---------HHGKHRQEES---LLGRTAMQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ES52-1", "uniprot_id": "SHIP1_MOUSE", "id": "Q9ES52-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1", "aln": "MPAMVPGWNHGNITRSKAEELLSRAGKDGSFLVRASESIPRAYALCVLFRNCVYTYRILPNEDDKFTVQASEGVPMRFFTKLDQLIDFYKKENMGLVTHLQYPVPLEEEDAIDEAEEDTVESVMSPPELPPRNIPMSAGPSEAKDLPLATENPRAPEVTRLSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLLLDSDFLKTGSSNLPHLKKLMSLLCKELHGEVIRTLPSLESLQRLFDQQLSPGL-RPRPQVPGEASPITMVAKLSQLTSLLSSIEDKVKSLLHE--GSESTNRRSLIPPVTFEVKSESLGIPQKMHLKVDVESGKLIVKKSKDGSEDKFYSHKKILQLIKSQKFLNKLVILVETEKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVIGTQEDPLGEKEWLELLRHSLQEVTSMTFKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWLGDLNYRVELPTWEAEAIIQKIKQQQYSDLLAHDQLLLERKDQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKNGPGTVDSQGQIEFLACYATLKTKSQTKFYLEFHSSCLESFVKSQEGENEEGSEGELVVRFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALR-LETTEAQHPIYTPLTHHGEMTGHFRGEIKLQTSQGKMREKLYDFVKTERDESSGMKCLKNLTSHDPMRQWEPSGRVPACGVSSLNEMINPNYIGMGPFG--QPLHGKSTLSPDQQLTAWSYDQLPKDSSLGPGRGEGPPTPPSQPPLSPKKFSSSTANRGPCPRVQEARPGDLGK--VEALLQEDLLLTKPEMFENPLYGSVSSFPKLVPRKEQESPKMLRKEPPPCPDPGISSPSIVLPKAQEVESVKGTSKQAPVPVLGPTPRIRSFTCSSSAEGRMTSGDKSQGKPKASASSQAPVPVKRPVKPSRSEMSQQTTPIPAPRPPLPVKS-PAVLQLQHSKGRDYRDNTELP---------HHGKHRQEEG---LLGRTAMQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92835-1", "uniprot_id": "SHIP1_HUMAN", "id": "Q92835-1", "name": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1", "aln": "---MVPCWNHGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPVPLEEEDTGDDPEEDTVESVVSPPELPPRNIPLTASSCEAKEVPFSNENPRATETSRPSLSETLFQRLQSMDTSGLPEEHLKAIQDYLSTQLAQDSEFVKTGSSSLPHLKKLTTLLCKELYGEVIRTLPSLESLQRLFDQQLSPGL-RPRPQVPGEANPINMVSKLSQLTSLLSSIEDKVKALLHE--GPESPHRPSLIPPVTFEVKAESLGIPQKMQLKVDVESGKLIIKKSKDGSEDKFYSHKKILQLIKSQKFLNKLVILVETEKEKILRKEYVFADSKKREGFCQLLQQMKNKHSEQPEPDMITIFIGTWNMGNAPPPKKITSWFLSKGQGKTRDDSADYIPHDIYVIGTQEDPLSEKEWLEILKHSLQEITSVTFKTVAIHTLWNIRIVVLAKPEHENRISHICTDNVKTGIANTLGNKGAVGVSFMFNGTSLGFVNSHLTSGSEKKLRRNQNYMNILRFLALGDKKLSPFNITHRFTHLFWFGDLNYRVDLPTWEAETIIQKIKQQQYADLLSHDQLLTERREQKVFLHFEEEEITFAPTYRFERLTRDKYAYTKQKATGMKYNLPSWCDRVLWKSYPLVHVVCQSYGSTSDIMTSDHSPVFATFEAGVTSQFVSKNGPGTVDSQGQIEFLRCYATLKTKSQTKFYLEFHSSCLESFVKSQEGENEEGSEGELVVKFGETLPKLKPIISDPEYLLDQHILISIKSSDSDESYGEGCIALR-LEATETQLPIYTPLTHHGELTGHFQGEIKLQTSQGKTREKLYDFVKTERDESSGPKTLKSLTSHDPMKQWEVTSRAPPCSGSSITEIINPNYMGVGPFGPPMPLHVKQTLSPDQQPTAWSYDQPPKDSPLGPCRGESPPTPPGQPPISPKKFLPSTANRGLPPRTQESRPSDLGKNAGDTLPQEDLPLTKPEMFENPLYGSLSSFPKPAPRKDQESPKMPRKEPPPCPEPGILSPSIVLTKAQEADRGEGPGKQVPA------PRLRSFTCSSSAEGRAAGGDKSQGKPKTPVSSQAPVPAKRPIKPSRSEINQQTPPTPTPRPPLPVKS-PAVLHLQHSKGRDYRDNTELP---------HHGKHRPEEGPPGPLGRTAMQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q0J1-1", "uniprot_id": "A0A8M9Q0J1_DANRE", "id": "A0A8M9Q0J1-1", "name": "phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase", "aln": "MFSPQP-WHHGNITRSKAEDLLSKAGKDGSFLLRDSESIQGAYALCVLYQNCVYTYRILPNDDKKLSVQASEGVPIRFFSALPDLVDAYYKENMGLITHLQYAVQKEEE-----PPEEEPEPLSLPPQLPPRNIFSNDSKESHNDPSRGTD--RGTEPSRLSISDTYFQRLQQIDISNLPEDHQKSIQEYFRASVCLDAEQVQNGNQTLPHFKKLTQNICKNLNSEIARTLPSFEALQKVLDQPLSPGAGRLRTQLSADANPS-VAFRLEQLTKLIQSIEDKTKNAVFEFVGYDGGHRNSLIPPVTFEVKSDSLGISNKMYLKVDVEGGKVYFKKSKDGPEDKYFVHNKILQLVKSQKMHNRLVLVVETEKGKTQSKDFVFDDTKKREGFCQLLQQMKNKHSGKPEPDMITIFVGTWNMGNANPPQNITSWFQSKGQGKTHDDTANQIPHDIYVIGTQEDPLGEKEWIETIRGALRDITNISFKQIATQTLWSIRIVVLAKPEHENRFSHIFSDSVKTGIANALGNKGAVGVSFMFNRTSFGFVNSHLTSGSEKKLRRNQNYVSILRFLNLGDKKVNPFDITHRFTHLFWLGDLNYRVDLPSHEAENIVMKIKQQQYKELLAQDQLKIEKDEEKVFLEYVEEEITFAPTYRFERDTRERYAYTKAKATGTKYNLPSWCDRVLRKSYPLVHVVCNSYGCTNDIMTSDHSPVFATFDVGVTSQFVSKND-LSNDARGAIKILNCVAVLCTKSKTKFFIEYHSSCLEKFVRSPDGENQE-MEGSIKVRFAG-QVELTPIIADPEYLLDQHILICIKSTDSDESYGEGCVALRSAESSYTEFSIT--LTHHGERTGWLTGAIQLPKSEGKQTEKLYDFIKVGDDPGAG----KGKTGDN----------TKMSSSVLASDISNPSYMGVGYKS---GIQAPGSLTSQR---------------------TGPSKDMTHGNISPKKTSYDHATSSPTAKTSNPIP-------VDGQP--------PEMFDNPLYGSMS-----------GSRGAKEHHPPPD-------ALFAFPKPTDFDS----DRQPPVP----TPRLRSYTCSETKPQSSSSTNLNMS------SLLPQSITKKPVVPSRSEGGMIGP----NRPPVPMKSRSGQTQEPQTKPRDYRDSSELPSKIRPPTRAGQTKDVHSETPPLKMGRQLK-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:**********:***::*******:* **** *******::***********:*.*::*******.:***: * :*:: * ******:****:.* *** . *: *.: **:****** . . . :: . .: *..* :* *:*:* *****.:* *.***:* *:**:*: :.: *:: ::.*...***:*** :**:* .*: *****:*:**:::** **** * *.*:..:*.* :. :*.***.*:.*****.* :.* * :. :* ***********::****.:** ******.**: .***:**.***:: *:*****:****: *:**::***** * *::** *:****************** :.********:******** **::***** *******:**:*: ***************.****:* :: :*:::*.::** :* :***.**************:*** :*.*******:************** **:*********************:.***** *****:.**:**********:*******:**: *** *: ******* :**::*** *: :::***.: ************** **::***** **** ************ **********:***.*.**************:.**********. : *::* *::* * *.* ***:***::* ******.**:* :***:* **.: *:*. :*.***:************.***:**********:*** *:: :: .* ****** ** : * *:* .*:** ******:*. * .:* *. *..: . .. .:: **.*:*:* . :: :*:.:: .*.. : :**** . *. . .:..:. * : ****:******:* * .:.*** . : :.*. : : .:* *. **:**:***.: .. : . . * . .*:*: ***** . . ***:*:** .. : ::* *****.:*** : *. .* :** ", "identical_positions": 628, "similar_positions": 273, "identity": "51.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-32", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZT56-1", "uniprot_id": "D3ZT56_RAT", "id": "D3ZT56-1", "name": "Zinc finger protein 687", "aln": "MTGLLANGEYESGQLGLGARRELRERGGRSGEKQEVAAAAGRAAAAAAAVAAGTGGGRRVSARTRIGTSLGPVTMGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGQGKPESSVGGDSKDREAATATENDPESAAEASDHGLPQPPDTSTVSVIVKNTVCPEQSETLTGNS-EEETKAGDVTKEGPVGSCLMQNGFGGPEPSLSETPHSSAPASGDAWEEKAGEGKTCLDLFAHFGSEPGDHTDPLPP-EPSLPRDGDMAPPPFSTPFELAP---------------ENGSTLLPPTSLLPQGALKQESCSPHHSQGLTQRNSGSSPEAAGVPASVSPPQVAGVS-FKQSPGHQSPPASPVKAPSCKPLKEED--EGTVDKSPPRSPQSPSS-----------------------------------------GAEAAD---------EDSNDSPTSSSSSRPLKVRIKTIKTSCGNITRTVTRVPSEPDPPAPLAEGAFLAEASFLKLSPVTPTPEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVARKAVVLPGGNATSPKTMTKNVLGLVPQTLPKAEVRTGFTLGGQKVNGASVVMVQPSKSATGPGTAGGSVISRTQSSLVEAFNKILNSKNLLPAYRPNLS--PPAEAGLALPPTGYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMRPVALDQMVGQPDITPLLPVAVPPVPGPLALPVLGKGEGAVTSSTITTVATEAPVLPLPTEPPAPPAASVYTCFRCLECKEQCRDKAGMAAHFQQLGPPALGSTSNVCPSCPMMLPNRCSFSAHQRTHKNRPPHVCPECGGNFLQANFQTHLREACLHFSRRVGYRCPSCAVVFGGVNS---IKSHIQASHCEVFHKCPICPMAFKSAPSAHAHLYSQHPSFLT--QQAKLIYKCAMCDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRVGEEAAGKGAGGALLTPKTEPEELAVSQAEAAPATEESSSTSEEE-LPSSPDPPRPAKRARR-ELGNKGIKGGGGGPGGWTCGVCHSWCPERDEYVTHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLPLGTQSSGRGGSLVRGSGGRAQGPGRKRRQSSDSCSEEPDSTTPPAKSLRGGPGSGGHGP-LRYRSSGSAEQS------LVG-LRVDGGTQQCLDCGLCFASPGSLSRHRFISHKKRRAGGKASVLGLGDGEEEAPPLRSDPEGG-DSPLPASGGPLT-------CKVCGKSCDSPLNLKTHFRTHGMAFIRARQGGSGDN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D2D7-1", "uniprot_id": "ZN687_MOUSE", "id": "Q9D2D7-1", "name": "Zinc finger protein 687", "aln": "--------------------------------------------------------------------------MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGQGKPEPSVGGDSKDREEAAAAENDPESPAEASDHGLPQPPDTSTVSVIVKNTVCPEQSESLTGDSGEEETKAGGITKEGPVGSCLMQNGFGGPEPSLSENPHSSAHASGNAWKDKAVEGKTCLDLFAHFGSEPGDHPDPLPP-EPSQPRGGDMAPPPFSTPFELAP---------------ENGSTLLPPASLLPQGALKQESCSPHHSQGLTQRGPGSSPETAGIPASVSPPQVAGVS-FKQSPGHQSPPASPVKAPSCKPLKEED--EGTVDKSPPRSPQSPSS-----------------------------------------GAEAAD---------EDSNDSPTSSSSSRPLKVRIKTIKTSCGNITRTVTRVPSEPDPPAPLAEGAFLAETSFLKLSPVTPTPEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVARKAVVLPGGNATSPKTMTKSVLGLVPQTLPKAEVRTGFSLGGQKVNGASVVMVQPSKSATGPGTAGGSVISRTQSSLVEAFNKILNSKNLLPAYRPNLS--PPAEAGLALPPTGYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMRPVALDQMVGQPDITPLLPVAVPPVPGPLALPVLGKGEGAVTSSTITTVATEAPVLPLPTEPPAPPTASVYTCFRCLECKEQCRDKAGMAAHFQQLGPPALGSTSNVCPSCPMMLPNRCSFSAHQRTHKNRAPHVCPECGGNFLQANFQTHLREACLHFSRRVGYRCPSCAVVFGGVNS---IKSHIQASHCEVFHKCPICPMAFKSAPSAHAHLYSQHPSFLT--QQAKLIYKCAMCDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRVGEEAVGKGAGGALLTPKTEPEELAVSQAEAAPATEESSSSSEEE-LPSSPEPPRPTKRARRGELGNKGIKGGGGGPGGWTCGLCHSWCPERDEYVTHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLPLGTQSSGRGGSLARGSGGRAQGPGRKRRQSSDSCSEEPDSTTPPAKSLRGGPGSGGHGP-LRYRSSGSAEQS------LVG-LRVDGGTQQCLDCGLCFASPGSLSRHRFISHKKRRAGGKASVLGLGDGEEAAPPLRSDPEGG-DSPLPAPGDPLT-------CKVCGKSCDSPLNLKTHFRTHGMAFIRARQGGSGDN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N1G0-1", "uniprot_id": "ZN687_HUMAN", "id": "Q8N1G0-1", "name": "Zinc finger protein 687", "aln": "--------------------------------------------------------------------------MGDMKTPDFDDLLAAFDIPDIDANEAIHSGPEENEGPGGPGKPEPGVGSESEDTAAASAGDG-PGVPAQASDHGLP-PPDISVVSVIVKNTVCPEQSEALAGGSAGDGAQAAGVTKEGPVGPHRMQNGFGSPEPSLPGTPHSPAPPSGGTWKEKGMEGKTPLDLFAHFGPEPGDHSDPLPPSAPSPTREGALTPPPFPSSFELAQ---------------ENGPGMQPPVSSPPLGALKQESCSPHHPQVLAQQGSGSSPKATDIPASASPPPVAGVPFFKQSPGHQSPLASP-KVPVCQPLKEEDDDEGPVDKSSPGSPQSPSS-----------------------------------------GAEAAD---------EDSNDSPASSSS-RPLKVRIKTIKTSCGNITRTVTQVPSDPDPPAPLAEGAFLAEASLLKLSPATPTSEGPKVVSVQLGDGTRLKGTVLPVATIQNASTAMLMAASVARKAVVLPGGTATSPKMIAKNVLGLVPQALPKADGRAGLGTGGQKVNGASVVMVQPSKTATGPSTGGGTVISRTQSSLVEAFNKILNSKNLLPAYRPNLS--PPAEAGLALPPTGYRCLECGDAFSLEKSLARHYDRRSMRIEVTCNHCARRLVFFNKCSLLLHAREHKDKGLVMQCSHLVMRPVALDQMVGQPDITPLLPVAVPPVSGPLALPALGKGEGAITSSAITTVAAEAPVLPLSTEPPAAPATSAYTCFRCLECKEQCRDKAGMAAHFQQLGPPAPGATSNVCPTCPMMLPNRCSFSAHQRMHKNRPPHVCPECGGNFLQANFQTHLREACLHVSRRVGYRCPSCSVVFGGVNS---IKSHIQTSHCEVFHKCPICPMAFKSGPSAHAHLYSQHPSFQT--QQAKLIYKCAMCDTVFTHKPLLSSHFDQHLLPQRVSVFKCPSCPLLFAQKRTMLEHLKNTHQSGRL-EETAGKGAGGALLTPKTEPEELAVSQGGAAPATEESSSSSEEEEVPSSPEPPRPAKRPRR-ELGSKGLKGGGGGPGGWTCGLCHSWFPERDEYVAHMKKEHGKSVKKFPCRLCERSFCSAPSLRRHVRVNHEGIKRVYPCRYCTEGKRTFSSRLILEKHVQVRHGLQLGAQSPGRGTTLARGSSARAQGPGRKRRQSSDSCSEEPDSTTPPAKSPRGGPGSGGHGP-LRYRSSSSTEQS------LMMGLRVEDGAQQCLDCGLCFASPGSLSRHRFISHKKRRGVGKASALGLGDGEEEAPPSRSDPDGG-DSPLPASGGPLT-------CKVCGKSCDSPLNLKTHFRTHGMAFIRARQGAVGDN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IYX6-1", "uniprot_id": "Z687A_DANRE", "id": "A0A0R4IYX6-1", "name": "Zinc finger protein 687a", "aln": "--------------------------------------------------------------------------MGDMKTPDFDDLLAAFDIPDIDAKEAIQSDTHGNHNEHSSVVGKERSGSPSLRPSGSPDPPHNDPSVVSVIVKNSVHSDDKAEGNETGEFSSADESQKSPQKGPSKDSSVPTDPFIYNGLKSVSDGSTESPPSLDLAPGQHNGPLWSLSASKATGDDDKHNDAFTNHPASTFQSLPLSNHPSVSSHLISPNFSSKVDSEEAQAINGTLRAGVRRHQSEDEESEPDLGSPALVIQESPISQLCPAPKVPRMQRSPSSVFQPPSPSSPSLPVSNTQMEEPSVQHPKLHSSTNPTSLTSTNNLPVEEKDLEHIIEERDSPESPEPEISQSRTSLPSNSQGAIESKQRITREEAPQDEVMDVSMQEKVDYGAEATEGKSTEPTLVESASDAISNSASSKPLKMRIKTVKKPVVSITRTVSKAATKGG-------ASKGSGASKVQAVARKSLQKIPRSVASPQLLSQSTKVAMLPVSTLQDASTAMLFAASRAQNQMPTALSATAVNITRTSNLPSISSSSIPGVNVRAAS---GQKTN---TGTAKPASIVNSP----GAVISRSQSSLVEAFNKILNSKNPLPSYQPDLTSLPPPEWGLRLPSTGYRCLECGDAFALERSLARHYDRRSMRIEVTCNHCSKRLAFFNKCSLLLHAREHKEKGLVMQCSHLVMSPVSVEQMIGQQDTVPIG-VLSPAVSALSAIKESGVN------------------------------LSQSSDHSCPECWSTFKGKQELVAHFQEVEPGGTDTCCLQCS-PPMPLWNSCCAAAHRRMHQQLPPLVCPECGLICQTHELNTHLKQTCLHYSRRLGYKCACCHLVFGGVNSQNAVKTHMQTAHCEIFHKCPSCPMAFKSSSGAESHCASQHPELSESARQSKEIYKCVMCRTVFTQKSLLSVHIDTHLTKQKMHVFKCPDCNKLFTQRTSLLEHVKDTHR-----------------ETSNHDGTSTQNSLVKMESSDGEEWGRDEEEDKGKVSDANSAVPRSQS-----------------WSCSQCQTHYTDKENYISHMTEQHGKELKKFPCTLCEGSFSSSSSLRRHIRVKHKGIKRVFYCQLCTGEKRSFSSKLILEKHIQAQHAGERGTATQSQAVPQFTDGADSSSEHDAGVLGGSSVEPESRLAESTLTRRIKGAPVGEQEAKGLRCMPCGFTTEDREEFLQHIVCHRDGGSGAQCQQCGACFASSSSLSRHLFISHRVRDSPSDHAEAALHTCATSVASDSAAAGGSPGSPLSVVGGLLEDGEGKHICKVCGRYFSKPADLNTHFRTHGMAFITAYKTDKPA-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***********************:***:*... *.. . : *. * :. ... :. . * : . : : . *..:: .. : : . . . : . . . *. .*. *. . * .: : .. :.* : * .. . . . * .* ::. . : *. . : .*. ..:.* . :*: .: . .. .* :.. *: . . .::. *.*. .:. . . *::*:* . ::..* **:. * ****:: *.:.*: :.*:* :***:****:*.. .*****::..:. . .: : :* :: . .. : *: *: . * ::***:*:*:******:*** *:: : . . :: :..: .: ..::* .: *:. ***.* . .:*:. ...* *:****:**************** **:*:*:*: **.* ** **.************:**:********************::**.***************:************ **:::**:** * .*: * *.*.. *: * . * : . * ** . :.* :.****:: * . .: . *. ** * * *. :**:* *:: .* ****** :::***:::*** ***:**:*..* :******* :*:*:*::***:***** *******...*.:* ****.: :*:* ****.** ****:*.*** *:* ** *:: *****.* **:*: ::***:*:**: *.: : . * .: *. . .*** . .:. .. *.: *:*. *:: .::::*::**.::***.:***** *** **.*:.*****:**:*:*****: *: ** **:***:******:*.:*. *: : .:. . ... :. . .*. .*. : :. :: :*.* . .. ** ... : :. : * .. ** :** ****..***** ****: * . .. : .* ... : . *. .***.. *. * *****: ..* :*:*********** * : ", "identical_positions": 427, "similar_positions": 370, "identity": "30.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-33", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "J3QNP2-1", "uniprot_id": "J3QNP2_MOUSE", "id": "J3QNP2-1", "name": "", "aln": "MASGRWNETTTSVY--LGFQVQQIHPFHDNWNTACFVILLLFIMTVVSLVVLAFLYEVLDCCCCAKNKTVKDLKSEPNPLRSMMDNIRKRDSEVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0DKX4-1", "uniprot_id": "SIM18_HUMAN", "id": "P0DKX4-1", "name": "Small integral membrane protein 18", "aln": "MASSHWNETTTSVYQYLGFQVQKIYPFHDNWNTACFVILLLFIFTVVSLVVLAFLYEVLDCCCCVKNKTVKDLKSEPNPLRSMMDNIRKRETEVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IP93-1", "uniprot_id": "A0A0R4IP93_DANRE", "id": "A0A0R4IP93-1", "name": "", "aln": "-----MNMSSSSAL------MQQIYPFHDGWNVACFIIILLFILTILSLATLAFLYELLDCGCFNKTKTVRDL--------------RRQHDEVV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :::*. :*:*:****.**.***:*:****:*::**..******:*** * *.***:** *::. ***", "identical_positions": 41, "similar_positions": 22, "identity": "43.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-34", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JII9-1", "uniprot_id": "CXCR3_RAT", "id": "Q9JII9-1", "name": "C-X-C chemokine receptor type 3", "aln": "MYLEVSERQVLDASDIAFLLENSTSPYDYGENESD-FSDSPPCPQDFSLNFDRTFLPVLYSLLFLLGLLGNGAVAAVLLSQRTALSSTDTFLLHLAVADVLLVLTLPLWAVDAAAQWVFGSGLCKVAGALFNINFYAGAFLLACISFDRYLSIVHATQIYRRDPWVRVALTCIVVWGLCVLFALPDFIFLSASHDQR-LNATHCQYNFPQVGRTALRVLQLVAGFLMPLLVMAYCYAHILAVLLVS---RGQRRFRAMRLVVVVVVAFAVCWTPYHLVVLVDI---LMDVGVLARNCGRESHVDVAKSVTSGMGYMHCCLNPLLYAFVGVKFKEQMWMLLMRLGRSDQRGPQRQPSSSRRESSWSETTEASYLGL---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88410-1", "uniprot_id": "CXCR3_MOUSE", "id": "O88410-1", "name": "C-X-C chemokine receptor type 3", "aln": "MYLEVSERQVLDASDFAFLLENSTSPYDYGENESD-FSDSPPCPQDFSLNFDRTFLPALYSLLFLLGLLGNGAVAAVLLSQRTALSSTDTFLLHLAVADVLLVLTLPLWAVDAAVQWVFGPGLCKVAGALFNINFYAGAFLLACISFDRYLSIVHATQIYRRDPRVRVALTCIVVWGLCLLFALPDFIYLSANYDQR-LNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILAVLLVS---RGQRRFRAMRLVVVVVAAFAVCWTPYHLVVLVDI---LMDVGVLARNCGRESHVDVAKSVTSGMGYMHCCLNPLLYAFVGVKFREQMWMLFTRLGRSDQRGPQRQPSSSRRESSWSETTEASYLGL---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49682-1", "uniprot_id": "CXCR3_HUMAN", "id": "P49682-1", "name": "C-X-C chemokine receptor type 3", "aln": "MVLEVSDHQVLNDAEVAALLENFSSSYDYGENESDSCCTSPPCPQDFSLNFDRAFLPALYSLLFLLGLLGNGAVAAVLLSRRTALSSTDTFLLHLAVADTLLVLTLPLWAVDAAVQWVFGSGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPPARVTLTCLAVWGLCLLFALPDFIFLSAHHDER-LNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILAVLLVS---RGQRRLRAMRLVVVVVVAFALCWTPYHLVVLVDI---LMDLGALARNCGRESRVDVAKSVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLLLRLGCPNQRGLQRQPSSSRRDSSWSETSEASYSGL---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BKS4-1", "uniprot_id": "A0A8M2BKS4_DANRE", "id": "A0A8M2BKS4-1", "name": "", "aln": "-----MAAPSNMEVELHGLFEKNNS-FDYDNYENK----ELDCQSKAVSDALGVFIPLLYSLGILLGLLGHGLVLAVLWHKWLNCSVMDIFIFHLSLIDSLLLLTMPLWAVDAVKGWIMGSGLCKLAGVLFKMNFYCSMLMLAFISVDCYLSIVHGVQKLSRKKPMVVHGCCLIIWLVCLLLSIPEWIFLKSISDSTDQVKDECIYFYPDDSWHRSSRFPHHVIFGVGTLVLLFCCTSIMLKLQRESMCQQKKIGRKTAIIAVLVLVFLICWTPYSIAFIVNTGARPVHIDPLTGESECEWRQWTASKITAIFGLLHCTINPVIYFCFSKEFRRRSQAVIKFNACESNNNDGSLWDSTADNVNTTVQEEQGPLQQVNELKPKVQTQQEDT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. *:*: .* :**.: *.. . * .. : .*:* **** :******:* * *** : * * *::**:: * **:**:*******. *::*.****:**.**::***.. ::** **.* **.***..* * * *: :* :*:*:::*::*:*.: *. .* * :*: . : . * : **: :* : *: * . : :: * ::.*:* .* :***** :..:*: :.:. *: :. * : .*..:*: :* :** :**::* .. :*:.: :: . .:.. .*: : . : * . ", "identical_positions": 107, "similar_positions": 117, "identity": "27.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-35", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P40809-1", "uniprot_id": "RG84C_DROME", "id": "P40809-1", "name": "GTPase-activating protein RacGAP84C", "aln": "-----------------------------------------MISGSGSRTP---------------------------------------------------------------------SNRLYLSPVRPTMQNKRRL--LREYRSYDDLS----------------------------EHYRMFGSQSLDSLQDRVDMNPSGCDG---------------------------LSTDGLDFCSQS----------------------------------------------------------------------HSGLLREHNFKIKSYYYNVGNCVHCRKRIRFAMASLRCRACPLRCHIGCCRQLTVNCIPQ---PQIGTKRGCLSDYAPRVAPMVPALIVHCVTEIEARGLQQEGLYRVSSTREKCKRLRRKLLRGKSTPHLGNK-DTHTLCCCVKDFLRQLVHPLIPIYHRRDFEEATRHEDRLAVEMAVYLAVLELHQAHRDTLAYLMLHWQKIAESPAVRMTVNNLAVIFAPTLFG------DLDLTLENVVTWQRVLKVLLLMPAGFWSQFLEVHPLPTSLGSTYD--------------FEDRYNHRHWDSSSNLGWSSVKTYFRSMVNLSSTHL----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z9I5-1", "uniprot_id": "A1Z9I5_DROME", "id": "A1Z9I5-1", "name": "Rac GTPase-activating protein 1", "aln": "-MALSALASFDDLRRCMQVLTDGTPEEEFLRFLRMFEQYHEKCAGYAAETARIQNELDKSLTKMGDLEGKLFHARRIIDMEIKARRQAEHERDAMESKIMAVADLLRHERN----LNNETRDKLAFLHTLPSSRKRKSLNAVREDKSYGDINSTGSLLSDLSITHSEDDFLDVRTSKSWREHRPSLPKNQIPSVGNKRSRLSTGLNGSMSGTTPTTGKSRRSSVGIGVEQHTVDVGQGAERFCATTKVTIPQDGQGVIRAESTIESLPVIAGNERIGDGLSSTPRRSVLKEATAPPLTPVNAMAPHVVAESGTPLQHRPLMRNHTFSQKTFLRGD-NCVQCQKRIRFGAVGLRCRDCPVRCHIDCRYLLTVSCVPQTGTPTTKTMTGYVTDFAPSIAPMIPALIVHCVNEIEARGLTEVGLYRLSSSEREYKALKEQFLRGKATPHLGNT-DIYVLCCCVKDFLRSLTEPLIPTSQWKDFANAVQNPDTKTAQDMLVKSVKQLPQANRDTLAFLILHFQRIAQCPVVLMPIDNISLIFGPTIVGYSTPDPDQHAIYTEVFTQKQVMKALLELPVSFWEQYIVIDPTRTPATVIKR--------------VPSNKNDLLSLYATPFKGGTIKKRKFYGTPPASAHKK---------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ACD6B6I5-1", "uniprot_id": "A0ACD6B6I5_DANRE", "id": "A0ACD6B6I5-1", "name": "", "aln": "MGDQFVREVLSLCLQRLAIEEASNSELEFIEVVRNFEAARKKWLHAELELKKQKELLVKSDVARAALEVKLKHARNQLDVEIKKRYKAEADYQCLERQMQLICDVLVHDSKSNACLNDEQRSMLTSFSHKGTCVPQHRGKRLSVIDESSFLSHSDISYDRTDDDLDLDSTAFVKPLKSRARERRRSSLGPVVSLPVPKRGRISGRSGDLLVSRPLEKEIETTVVKASVSTPETGSQIHMVIDITQEAPEHPSRALRNEHFSSVAEQTSVWAHSEVIQAETMVEMEVSAVEPAVLQDLTP-----------------TVEKTVQHVFQQKTVIRPE-TCMPCGKRIRFGKLAVKCRDCRVVSHPECKHLCPERCCPN-AHGSSHPNEETLESFAPSTRPRIPSIIVQCVHEIERRGLEEKGIYRVPGGERQVKELREKYLYGKGPLMLHKVDEVHAVCGLLKDFLRKLSEPLITFKLHRTFMEASEMADEDKSVETLLKTIRELPQPNRDTLAFLMLHLQRVMQSPLCQMDLNNLSRVFGPTIIGHAMSEPSPMTIMRDTNTQPRVVARLLSFPSDFWEGFLAEENDPVNPPVIETNIASVCPSTSRDKIFKPLTSPELSKYSKTTSGGSIKGRIKHFGGTFNNPSKPRNEPGKKKFFTSPK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * : :: : . . :. .. : *: :* .* : :* *. *: .*: * *****. .::** * : .* * . * *: . : .:** * :*::**:** *** *** : *:**:.. ..: * *:.: * **.. * : : :.:* :*****.* .***. : * :* . * : :: :* *.:*****:*:** *:: :.* * ::*:: :*.**:.* . :. * :*: ** :* .**. :: . . . . :. .::* . ", "identical_positions": 83, "similar_positions": 103, "identity": "12.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-38", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y468-5", "uniprot_id": "LMBL1_HUMAN", "id": "Q9Y468-5", "name": "Lethal(3)malignant brain tumor-like protein 1", "aln": "----------------------MHLVAGDSPGSGPHLPATAFIIPASSATLGLPSSALDVSCFPREPIHVGAPEQVAGCEPVSATVLPQLSAGPASSSTSTVRLLEWTEAAAPPPGGGLRFRISEYKPLNMAGVEQPPSPELRQEGVTEYEDGGAPAGDGEAGPQQAEDHPQNPPEDPNQDPPEDDSTCQCQACGPHQAAGPDLGSSNDGCPQLFQERSVIVENSSGSTSASELLKPMKKRKRREYQSPSEEESEPEAMEKQEEGKDPEGQPTASTPESEEWSS-----SQPATGEKKECWSWESYLEEQKAITAPVSLFQDSQAVTHNKNGFKLGMKLEGIDPQHPSMYFILTVAEVCGYRLRLHFDGYSECHDFWVNANSPDIHPAGWFEKTGHKLQPPKGYKEEEFSWSQYLRSTRAQAAPKHLFVSQSHSPPPLGFQVGMKLEAVDRMNPSLVCVASVTDVVDSRFLVHFDNWDDTYDYWCDPSSPYIHPVGWCQKQGKPLTPPQDYPDPDNFCWEKYLEETGASAVPTWAFKVRPPHSFLVNMKLEAVDRRNPALIRVASVEDVEDHRIKIHFDGWSHGYDFWIDADHPDIHPAGWCSKTGHPLQPPLGPRE-PSSASPGGCPPLSYRSLPHTRTSKYSFHHRKCPTPGCDG----SGHVTGKFTAHHCLSG--CPLAERNQS---------------------------------------------RLKAELSDSEASARKK------NLSGFSPRKKPRHHGRIGRP-----PKYRKIPQEDFQTLTPDVVHQSL-----------------------FMSALSAHPD--RSLSVCWEQHCKLLPGVAGISASTVAKWTIDEVFGFVQTLTGCEDQARLFKDEARIVRVTHVSGKTLVWTVAQLGDLVCSDHLQEGKGILETGVHSLLCSLPTHLLAKLSFASDSQY-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2A5N8-1", "uniprot_id": "LMBL1_MOUSE", "id": "A2A5N8-1", "name": "Lethal(3)malignant brain tumor-like protein 1", "aln": "MEGHTDMEILRTVKGSSTGEVNVHLVARDSAGPHPQLPTTAFIIPTNAATLGLPSTALDVP-YPREPVHVGALERVAGSEPVTATILPQLSTG--TGTNSTVRLLDWTGVSAPLPGSGMRFRINEYAPLNMIGVERPRSPEQRHEGGMARRDAG----------IQHPDVHQDRQDITSLEPPVDASSCKCQACGPQQSSGLDVGSSGDRCSQPFQKRSVIVENS-GCTIASELLKPMKKRKHKEYQSPSEE-SEPEAVK-QGEGKDAEREPTPSTPENEEWSR-----SQLVSSEKKDGWSWESYLEEQKAVTAPVSLFQDSQAVTHNKNGFKLGMKLEGIDPQHPSMYFILTVAEVCGYRLRLHFDGYSECHDFWVNANSPDIHPAGWFEKTGHKLQLPKGYKEEEFSWSQYLRSTKAQAAPKHLFVSQSHSTPPVGFQVGMKLEAVDRMNPSLVCVASVTDVVDSRFLVHFDDWGDTYDYWCDPSSPYIHPVGWCQKQGKPLTPPQDYPDPDSFCWEKYLEETGTSAVPNWAFKVRPPHSFLVNMKLEAVDRRNPALIRVASVEDVEDHRIKLHFDGWSHNYDFWIDADHPDIHPAGWCSKTGHPLEPPLRPRE-SSSVSPGGCPPLSHRSPPHTKTSKYNFHHRKCPTPGCDG----SGHVTGKFTAHHCLSG--CPLAEKNQS---------------------------------------------RLKAELSDSETAARKK------NPSNLSPRKKPRHQGRIGRP-----PKYRKIPEEDLQALPPSVVHQSL-----------------------FMSTLPTHAD--RPLSVCWEQHCKLLPGVAGISASTVSKWTIEEVFGFVQTLTGSEDQARLFKDEM-------IDGEAFLL-------LTQADIVK----IMSVKLGPALKIYNAILMFKN---TDDAFK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZJT9-1", "uniprot_id": "D3ZJT9_RAT", "id": "D3ZJT9-1", "name": "", "aln": "----------------------MTESSST---TSGQEFDVFSVMDWKDGVGTLPGSDLKFR-----VNEFGALEVITDESEMES----------VKKATATTTWMVPTAQDAPP-----SPLSSRPAFPPAYWTSPPGCPTVFSEKTGVPFRLKE---------------------QSKVDGLQFCENCCQYGNGEECLSGGNYCSQN--CSRRARDKDQKEDRDGGEDNDEEDPKCSRKKKPKLSLKADSK--EDEERDDEMENKQDGRILRGSQRARRKRRGDSAVLKQGLPPKGKKTWCWASYLEEEKAVAVPTKLFKEHQSFPYNKNGFKVGMKLEGVDPEHQSVYCVLTVAEVCGYRIKLHFDGYSDCYDFWVNADALDIHPVGWCEKTGHKLRPPKGYKEEEFNWQSYLKTCKAQAAPKSLFENQNITVIPSGFRVGMKLEAADKKSPSIICVATVTDMVDNRFLVHFDNWDESYDYWCESNSPHIHPVGWCKEHRRTLITPPGYSHVKHFSWDKYLEETNSLPAPARAFKVKPPHGFQKKMKLEAVDKRNPLFIRVATVADTDDHRIKVHFDGWSSCYDYWIDADSPDIHPVGWCSKTGHPLQAPLSPAELMEPSETGGCPTLGCRGVGHFKKSRYLGTQSGANCPYSEINLSKDRIFPDRLSGEITPSSFSFPRSKRTDTNESSSSPETRDQHANNVKEDSEKKKENEVKTSAEAKVVREEPTPSVQQTQPPQQALKAPQAPQIQPAQQAPQAPQAQPTQQQAQQAQQAPQAPQAQPAPQAPQTHPTQQQAQQAQPTQQQAQQAQPTQQQQAQQQAQRRSAVFLSFKPPIPCLPLRWEQQSKLLPTVAGIPASRVSKWSTDEVSEFIQSLPGCEEHGKVFKDEQ-------IDGEAFLL-------MTQTDIVK----IMSIKLGPALKIFNSILMFKAAEKNSHNEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9QEX7-1", "uniprot_id": "E9QEX7_DANRE", "id": "E9QEX7-1", "name": "", "aln": "----------------------MAETSVSDGPATGGDFDMMSALDWKDGIATLPGSDIRFR-----MTEFGTLEIVTEAEPKIK----------ETELTDPQPKITGPINRHPPDLNTTSNQTAKIQSNTDHQTSTPASTEPQRQAGGDSSTVDNP-----------IINTVPNAIVPVTEAPINCRTCGLSGSRESFLQG-KFCSAS--CVQPSSGRSTPAEAFEGERLG----KRVRKKK-KMFMESEDE--EEENIEEEEERVKSSKGRRAAKVAR----------LVTAPLVKKKTWSWSVYLEEERAAAAPLKLFKEHQSFPQSRNGFKVGMKLEGLDPCHPALFCVLTVAEVQGYRIRLHFDGYPECYDFWVNADSWDVKPPGWCEKTSLKLLLPKGCRDGEFNWNTYVKNCRGQLAPKHLFKSLNTSVTPSGFRAGMKLEAVDRKNLSDICVATIAAAVDNRLLIHIDHCDDTHDYWCDASSPYIHPVGYCEEVKLTLTTPAEYKHLKGFSWEKYLEETGTQAAPARAFKQRPPHGFQVGVKLEAVDKRNPMLIRVATISDTEEHRIKIHFDGWSDEYDYWLDADSPELHPVGWCQKTGHPLQHPNGTRDSPVPPGQG-CPTPGCNGVGHIRGPRYGTHYTAVSCPYSDLNFNKDGLVPDRLSGERPVTISGPPRHRRAET---------------------------------------------LTQTHQPTSSASTPEP----PDTTTDACPQARPVREHVVTAA----APKCVKAPQVKQEGDGKDSLQQFL-----------------------HESVFCGWEQ--PRFQLCWEKHGKLLPEALGLTAKRVSKWNTEEVASFVRGLPGCREHAPTFRKEQ-------IDGEAFLL-------LTQSDIVK----ILSIKLGPALKIYNSILMLKSADEE-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : . . **.: : . ..*: * :: . . . . : . * . .. * .. : . : .* . * . * . * : :. : * * :*:* : ....: * * . : * . : . *. *.* ****::* :.* .**:: *:.. .:****:******:** * ::: :****** ***::******.:*:******:: *::* ** ***. ** *** :: **.*. *::. :.* *** ** . . : * **:.******.*: . * :***::: **.*:*:*:*. .:::****:..**:*****:*:: .* .* * . . *.*:******.: ..* *** :***.* :******:*** :****:: *.::****:****** **:*:*** *::**.***.******: * . : . * **. . .. * : .:* * .: . ...:::.. : * .: :: ::. . . : : : .*: :* :. *: *: . :* :.: : : **:: **** . *:.*. *:**. :** *:: *.*..::. *:.* :.*:::: :. :* :: *:. : . * : *: * ", "identical_positions": 216, "similar_positions": 229, "identity": "22.59%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-39", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5LJX8-1", "uniprot_id": "Q5LJX8_DROME", "id": "Q5LJX8-1", "name": "", "aln": "------------MMRIRN-MKSSIS-------HILLFCYI------------------------------------------NCTQPAIDDFPRDLFSEAQRQSGAVVLHVIASLYLFVALAVVCDEYFVPAVEKICAALNMSNDVAGATFMAAATSAPELFVNVIGTFITEGDIGVGTIVGSAVFNILAVAACCGIGAGMTIPLDWWPLTRDSIAYGVTVAILICVMHDERVEWYEALILVSLYAVYLAVMYFD--------KTF----QKCAKGGVKQARSRSRSS-NCS----IHTKNSNEKEPE----LVENRICQN-----MANIQLNGGLNKEQAKATSTSGAGTTAISITTSTMTTTLSTTHSAGGGGGAVG------------LCSGPGAIVQMAPLDD-------------AEAESHVAVAAADEGRKEEGYSLLSYPKDKSCFAQFTWLIIWPIHLLFRIAIPDCKKAKNNKIFPLTFIMCIVWIGSLSYVVAWMITIIGDTLKIPDSVMGITFLAAGTSVPEAVSSVIVAKRGHGSMGICNSIGSNTFDILLCLGVPWLIKAVFFPIQPGQNYVAINSAGLEYSAITLLSTLFLLYLTFSTNKFKLDKKVGTACLVMYLVFMVFASLIELNVFFRVNLPTCGRS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M9PYK8-1", "uniprot_id": "A0A8M9PYK8_DANRE", "id": "A0A8M9PYK8-1", "name": "", "aln": "MKEEGFSLGWRCFKRCGGGMKAVLTSRRQRLFYRLFICAVGLIAVTCFAQILHVTEHSKEESDQNWARRKLTQQIIEENQTSSTPRAAIHEFPQDIFTKGQRRHGAILLHVFCAVYMFYALAIVCDVFFVPSLEKICENLHLSEDVAGATFMAAGSSAPELFTSLIGVFITKGDLGVGTIVGSAVFNILVIIGVCGIFAGQTITLTWWPLFRDSIFYILSVLALILIIYDEKVIWWETIILISMYGVYILIMKFNSQIWGWVEQRFGIPGQPCLVSSLRRDVSVGEASPHCDTSMILLKKGQNAGGQDSPVVMVDELMSLHPHQFSFSEASLRVMITPHFSPRTRLSMAGRMLITERQRLIRNRSPGDSSGSGAGDTPGQDGPGMEAVPWGLENGGALESETQPLEEPRRRSQGGELERVADIEDTQPKDDEEDEEEADEEPFRPFTVPEGRWEQAKWMFSWPLSCLLYYTVPNCVLPRWERWFMVTFVASTLWIAVFSYLMVWMVTIISFTLDIPDVVMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNIFDILLGLGFPWALRTLVVDYG---STVSINSKGLVYSVILLLASVFLTVLSVHLNHWRLDRRLGLGLMFLYAIFLLCSICFEKL-------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . **: :: : *::* : . .:.**.:**:*:*::.**: **::***:.::*:* ***:*** :***::**** *::*:**********.:******..:**.***:**:**************.: . *** ** **.* **** **** * ::* ** :::**:* *:*::**:*:*.**: :* *: : * * * ..::: * ..:* :*. : .*..* : :*:: :. : ::: .*. :. . : * * ** *: : . . *..*.*.: * * .* . : **:: *: *. . :: .: : .: .:. :. : * .*:: **: *: ::*:* .: :: * :**: . :**. :**::.**:***. **.*** **************:.::*:***::* *.*.:.****** ***** **.** ::::.. . *:*** ** **.* **:::** *:. *:::**:::* . :.:* :*:: : :* ", "identical_positions": 211, "similar_positions": 188, "identity": "32.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-43", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ESG4-1", "uniprot_id": "CLTRN_MOUSE", "id": "Q9ESG4-1", "name": "Collectrin", "aln": "---------------MLWALFFLVTTIHAELCHPDAENAFKVRLSIRAALGDKAYVWDTDQEYLFRAMVAFSMRKVPNREATEISHVLLCNITQRVSFWFVVTDPSN-NYTLPAAEVQSAIRKNRNRINSAFFLDDHTLEFLKIPSTLAPPMEPSVPVWIIVFGVIFCIVTVAIALLVLSGIRQRRRNNKGPPGVEDAEDKCENIITIENGIPCDPLDMKGGHINDGFLTEDERLTPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBJ8-1", "uniprot_id": "CLTRN_HUMAN", "id": "Q9HBJ8-1", "name": "Collectrin", "aln": "---------------MLWLLFFLVTAIHAELCQPGAENAFKVRLSIRTALGDKAYAWDTNEEYLFKAMVAFSMRKVPNREATEISHVLLCNVTQRVSFWFVVTDPSK-NHTLPAVEVQSAIRMNKNRINNAFFLNDQTLEFLKIPSTLAPPMDPSVPIWIIIFGVIFCIIIVAIALLILSGIWQRRRKNKEPSEVDDAEDKCENMITIENGIPSDPLDMKGGHINDAFMTEDERLTPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QQZ6-1", "uniprot_id": "F1QQZ6_DANRE", "id": "F1QQZ6-1", "name": "", "aln": "MRVKVQMPSGEMITGFLLTIILLSPVVAQDLCK-ESKDGFKVRISLKTALGNDAYEWNESEKFLFRSTLAYAMRKKTGEDTYNIENILVCNDTKRVSFIFVVTLPADPTQLIPKEEVERAVRQSKHRINNAFLLSDMTLEFVGVPPTLAVPIQYNTPPWLIVFGVVIGIVAVGIVALLMSTVSKRRRAKAKDAGFDQDGD--DEGIVKENGTALSGLNKKDGVYNQAFSN-DERFTKL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :::* ..: :**: :::.****:*:::***:.** *: .:::**:: :*::*** ...:: :*.::*:** *:**** **** *:. . :* **: *:* .::***.**:*.* ****: :*.*** *:: ..* *:*:***:: *: *.*. *::* : :*** : . .:: * :: *. *** . . *: *.* *:.* . ***:* *", "identical_positions": 85, "similar_positions": 86, "identity": "35.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-46", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62187-1", "uniprot_id": "TTF1_MOUSE", "id": "Q62187-1", "name": "Transcription termination factor 1", "aln": "MKGGTSKFKTHTETLYKKKKWSSVSEKRPQKCPSQCLE-----SKQPQVSVLGKRRRASQTPAQETLES---------EWPQKAKRKKRRREPQTPAQET------LESEWPQKAKKKKRRGEPQTPTQESLESEQPPVSLLGKRRRESQTPAQENSESEQPRKAKRRRKKRKGSQQPTSSLLKTPETFLKAKKTTSAHKKKKNSVLEVDMETGIILVDKENMENLLETSRKDVDIVYVDMSKGQRSA-----KVRETGELPAAKPQEHGCRELLGDVRSRKKQKHLQKVAPWDVVQGSQP-ESISLPPSEPLSSEDLEGKST-EAAVFCKKKSKKNVFRS--QELEPIPDSLDDSETISERLDSTHHGGAVGAGEECESTKESHSIKKKSKKKKHKSVALATSS-DSASVTDSKAKNALVDSSEGSGAVREEDVDHRPAEAEAQACSTEKHREAMQRLEPTHEEESNSESASNSAARHISEDRRESDDSDVDLGSAVRQLREFIPDIQERAATTIRRMYRDDLGRFKEFKAQGVAIRFGKFSAKENKQIEKNVQDFLSLTGIESADKLLYTDRYPEEKTLITNLKRKHAFRLHIGKGIARPWKLVYYRAKKIFDVNNYKGRYNEEDTKKLKAYHSLHGNDWKKIGAMVARSSLSVALKFSQIGGTRNQGAWSKAETQRLIKAVEDVILKKMSPQELRELDSKLQEDPEGRLSIVREKLYKGISWVEVEARVETRNWMQCKSKWTEILTKRMTHGGFVYRGVNALQAKITLIERLYELNVNDANEIDWEDLASAIGDVPPPFVQAKFYKLKAACVPFWQKKTFPEIIDYLYKNSLPLLKEKLDKKMKKKDGQIQTPAAPKQDFLFKDIFHCDDDSDEGSPEEPSASDVQ-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15361-1", "uniprot_id": "TTF1_HUMAN", "id": "Q15361-1", "name": "Transcription termination factor 1", "aln": "MEGESSRFEIHTPVSDKKKKKCSIHKERPQKHSHEIFRDSSLVNEQSQITRRKKRKKDFQHLISSPLKKSRICDETANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDVDVVCVDMSIEQKLPRKPKTDKFQVLAKSHAHKSEALHS--KVREKKNKKHQRKAASWESQRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKSRPRQKKTQACLASKHVQEAPRLEPAN-EEHNVETAEDSEIRYLSADSGDADDSDADLGSAVKQLQEFIPNIKDRATSTIKRMYRDDLERFKEFKAQGVAIKFGKFSVKENKQLEKNVEDFLALTGIESADKLLYTDRYPEEKSVITNLKRRYSFRLHIGRNIARPWKLIYYRAKKMFDVNNYKGRYSEGDTEKLKMYHSLLGNDWKTIGEMVARSSLSVALKFSQISSQRNRGAWSKSETRKLIKAVEEVILKKMSPQELKEVDSKLQENPESCLSIVREKLYKGISWVEVEAKVQTRNWMQCKSKWTEILTKRMTNGRRIYYGMNALRAKVSLIERLYEINVEDTNEIDWEDLASAIGDVPPSYVQTKFSRLKAVYVPFWQKKTFPEIIDYLYETTLPLLKEKLEKMMEKKGTKIQTPAAPKQVFPFRDIFYYEDDSEGEDIEKESEGQAPCMAHACNSSTLGGQGRWII", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A286YBY6-1", "uniprot_id": "A0A286YBY6_DANRE", "id": "A0A286YBY6-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------MDEMPSLSSNDCNDRVGGKKVKKKKKRSKSTEQHELTESPQEQTEKRRKKKKRRNSIQETDSNLQT--------------------------------------KKRRKLDKEGETSVMDDG---------------VSNQHEEQTQELQGSREGKTSKRKKKREK--------------------------------------------------------------------------------------LKQTQELQGSREGKTSKRKKKREKLKQTNCEDIT-------------------------------------KEQTDIRTEHEEEPNTSDPPDLIITDKKRESKTPKNNIDS-------------KFMEELNEWVPKMKLRCKSYMNDIIRYELSRFKEFRKQGIEMRTGRFSTAENERLRQNVNNFMALTGVTDAVKLFFPSRYPKEANALRKLKKKHRFFESIADGIPRFCNDVYDRGARVYDDRNYKGHFSEEEVKLLLKYYKRYGRDFKKISDKTNRSCRSLESRLLFITERK--GPWSSKEVQRLLRAVRDYVVSVLKSANPNQRKPKR---------VNKEILYKKLPWTKIAGQVKTRCWMTCKSKWMTILTARMSSG-TTFRGRKSQEAKIKLIKAMYELQVEDAVDVPWEDLTAVFGDVLPSYVQSRWHKLKVNHVPDWKNKSFADIVDFLYENVLPGLVKDCEDLDDD-----ELKVDQMNSFRLADIFQDINEDECCDSDEETGQQEKSSSA---------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : * : : . .. .. : :.:::*:: : . :: :: . .:: . : : . : * . . :.:*::. : :. :*.:: *:*.*:.* ... : : *: :* : :*.. : : ..: . :. . :.:*.*::*.:: *. : :. : * :* *****: **: :: *:**. **:::.:**::*::***: .* **::..***:* . : :**::: * *. .*.* : :* *. :::* .****::.* :.: * *:. *.*:*.*. . **. *: :: * : *.**. *.::*::**.: ::. :.. : .: ..* : :* *** :.*.:: .:*:** ** ***** *** **: * : * :: .**:.**: :**::*:*: :: ****::.:*** *.:**::: :**. ** *::*:*.:*:*:**:. ** * :. :. .. : . : * : *** ::.: . :: : : ", "identical_positions": 133, "similar_positions": 227, "identity": "14.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-48", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70596-1", "uniprot_id": "KCJ14_RAT", "id": "O70596-1", "name": "ATP-sensitive inward rectifier potassium channel 14", "aln": "-------MGLARALRRLSGALEP---------------GNS------------------------RAG----------------DEEEAGAGLCRNG--------------------------WAPGPVAG---------NRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLTFWLIASLHGDLAAPPPP------------------------------APCFSQVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDRRLCLMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELAR-ADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRG--SQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQASHSPKSSFPGSLAAFCYENELALSCCQEEDEEEDTKEGTSAETPDRAASPQALTPTLALTLPP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8JZN3-1", "uniprot_id": "KCJ14_MOUSE", "id": "Q8JZN3-1", "name": "ATP-sensitive inward rectifier potassium channel 14", "aln": "-------MGLARALRRLSGALEP---------------GNS------------------------RAG----------------DEEEAGAGLCRNG--------------------------WAPGPVAG---------SRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLTFWLIASLHGDLAAPPPP------------------------------APCFSQVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELAR-ADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRG--SQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQASHSPKSSFPGSLTAFCYENELALSCCQEEDEEEDTKEGTSAETPERAASPQALTPTLALTLPP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UNX9-1", "uniprot_id": "KCJ14_HUMAN", "id": "Q9UNX9-1", "name": "ATP-sensitive inward rectifier potassium channel 14", "aln": "-------MGLARALRRLSGALDS---------------GDS------------------------RAG----------------DEEEAGPGLCRNG--------------------------WAPAPVQSP-------VGRRRGRFVKKDGHCNVRFVNLGGQGARYLSDLFTTCVDVRWRWMCLLFSCSFLASWLLFGLAFWLIASLHGDLAAPPPP------------------------------APCFSHVASFLAAFLFALETQTSIGYGVRSVTEECPAAVAAVVLQCIAGCVLDAFVVGAVMAKMAKPKKRNETLVFSENAVVALRDHRLCLMWRVGNLRRSHLVEAHVRAQLLQPRVTPEGEYIPLDHQDVDVGFDGGTDRIFLVSPITIVHEIDSASPLYELGRAELAR-ADFELVVILEGMVEATAMTTQCRSSYLPGELLWGHRFEPVLFQRG--SQYEVDYRHFHRTYEVPGTPVCSAKELDERAEQASHSLKSSFPGSLTAFCYENELALSCCQEEDEDDETEEGNGVETEDGAASPRVLTPTLALTLPP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HF78-1", "uniprot_id": "A0AC58HF78_DANRE", "id": "A0AC58HF78-1", "name": "G protein-activated inward rectifier potassium channel 3", "aln": "-------MGAARVKRRFSAVVDTPLDEEEVMRLAQSDDGTSSHSGTLPSPNCNGKVLSILHSNGGRSGERDEDEDDDDDADKDDDDEEEGGGRRGGGGRGSALSGESGVEGRWERNKRASLPSLSPTPLRDRR----RQSRRPRRRFVGKDGRCNVTFVNMSERGQRYLTDLFTTCVDIRWRWMLVVFTLSFLLTWLLFGFTFWLIAAAHGDLNPLASSSSSPSSLSSSLAPLDATEGSSRVEMVAETEEPCFQQVNSFMAAFLFSLETQTSIGYGFRSVTEACPLAVLAVVLQCIVGCIIDAFIIGAVMAKIAKPKKRNETLVFSDVAVVAVRDGKLCMMWRVGNLRKSHLVEAHVRAQLLKPRVTPEGEFLPLDNSDLNVGFDTGTDRIFLVSPVTIVHEINEESPFFEMDKGALEGDKDLEVVVILEGMVEATAMTTQCRSSFLASEILWGHRFEPVLFERK--NCYQVDYSYFNRTYEVTDTPTCSAKELAE---------KKYIAGSRSSFCYENEVALQLSSSVPPCADQFSPSPCSSPPQSPTPPPRQDSCSEHPHKH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4LHI9-1", "uniprot_id": "A0A0B4LHI9_DROME", "id": "A0A0B4LHI9-1", "name": "", "aln": "MRFNFSTHSAAPTSTTIPTTTQANGGEQATQPLKKAIEADP------------------------DSLDSVISNPQSYPITIVPNRPTSYYGLSQNG------------------------KPFPRQPSCRSRNFRPGSMRRVRRRAVFKNGDCNVVQKHLQRRRVRFLQDMYTTMVDWQWRWTLLAFALSFILSWLFFALIWWLIIYTHGDLEEPHLPENQEES----------------------GWAPCVSAIDGFTSCFLFSIETQHTIGYGVRTTSPECPEAIFMMCFQSIYGVMSSAFMAGIVFAKMTRAKQRAQTLLFSKHAVICQRDGTLSLMFRVGDMRKSHIIGAGVRAQLIRTKSTKEGEVMTQYFTELEIGTDDSGSDLFFIWPMVIEHKIDENSPLYNLNATDMLQ-DKFEIVVILEGTVESTGQSTQARSSYINTEILWGHRFDPVVLYNKDLQAYEIDYARFNETTQVD-TPLCSARELNE------------IYKIQEGFRTPAETTFTMRQLSHNHSDQAS---------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7YZX2-1", "uniprot_id": "B7YZX2_DROME", "id": "B7YZX2-1", "name": "", "aln": "MQSDASPLGAAATDSLTMHRSTSMPVKPKPLEQKPLLRSSEK-----------------------ETVNASDYYPESPGFVRRRRSKAAGDHLETRSEQNPTFSFPYAHDWAG------STIELTPDLGSGPRTSSSDGLRRSLNRVMEKNGKENVVFRRIPEKSWRYMRDLVTTLMELEWKYMLTLFLGSYFLSWLLFAALCYVVAYSHGDFIFDPVSGKRMGEG----------------------VDPCIYGVHSWVAMIIYSVETQTTLGFGEKYASEECPETIFLFVMQMLSAALIEGCMVSVIYAKTARPARQLTKLKFSDKAVICYRDGRLCLLFRVCDPREQQSIESKIRVYIIVDKRTREGETIKS---HVELKLEGNGE-QIILWPDVVCHVIDETSPLSQFTTAKLFNAAQFELYVSIVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYDAQNERYIVDYENFNRTISVDMPMTNPK---------------------------NDHLKLEYRK-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . . . : . . * * : *:* ** .: : *:: *: ** :: .*:: * *:: :**:*. ::: ***: . **. : .: : :::::*** ::*:* : .: ** :: . :* : . : .. : . : ** ::. :: .* **. **:. ** *.:::** : *..: : : :*. :: : * *** : .::: : . . ::: * .: * *:. **: :: : .:*: * : * :*. *:.::*:: *::**:** :: . * :** *:.* .* . . . : . ", "identical_positions": 70, "similar_positions": 128, "identity": "12.39%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-51", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C0K7-1", "uniprot_id": "EPHB6_RAT", "id": "P0C0K7-1", "name": "Ephrin type-B receptor 6", "aln": "-------------------------------------------------MASENTAGSGSR-VAGMVYSLWLLVLGPSVLALEEVLLDTTGETSEIGWLTYPPG------GWDEVSVLDDQR-RLTRTFEACHVAGLPPGSGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYYRQADEPD------SPDSISAWHLKRWTKVDTIAADESFPASSSSSS------WAVGPHRTDQRVGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVKLFSYTCPSVLRAFASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGRWMVAVGGCRCQPGHQPARGDKLCQACPEGSYKALPGNVPCSPCPARSHSPDPAAPVCPCLQGFYRASSDPPEAPCTGPPSAPRELWFEVQGS--ALMLHWRLPQELGGRGDLLFNVVCKECGGHKEPSSGG--MCRRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQ--------------------------------AAAINVSTSHEVPSAVPVMHQVSRAANSITVSWPQPEQTNGNILDYQLRYYDQAEDESH-SFTMTSETNTATVTRLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPEKLSLVIGSILGALAFLLLAAITVLAVIFQR-----KRRGTGYTEQLQQYSSPGL----------------------GVKYYIDPSTYDDPCQAIRELAREVDPTYIKIEEVIGAGSFGEVRRGRLQPRG--RREQAVAIQALWAGGAESLKMTFLGRAALLGQFQHPNILRLEGVVTRSRPVMVLTELMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRALSARSVLVNSHLVCKVARLGHS---------------PQGSSSLLRWAAPEVITHGKYTTSSDVWSFGILMWEVMSYGERPYWDMSDQEVLNAIEQEFRLPPPPGCPTGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAEGSSGDRPSQALLNPVALDFPCLDSPQAWLSAIGLECYQDNFSKFGLSTFSDVAQLSLEDLPGLGITLAGHQKKLLHNIQLLQQHLRQPGSVEV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08644-1", "uniprot_id": "EPHB6_MOUSE", "id": "O08644-1", "name": "Ephrin type-B receptor 6", "aln": "-------------------------------------------------MATEGTTGSGSRVVAGMVCSLWLLVLGSSVLALEEVLLDTTGETSEIGWLTYPPG------GWDEVSVLDDQR-RLTRTFEACHVAGLPPGSGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYYRQADEPD------GPDSIAAWHLKRWTKVDTIAADESFPASSSSSS------WAVGPHRTGQRVGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVKLFSYTCPSVLRAFASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGRWMVAVGGCRCQPGHQPARGDKLCQACPEGSYKALAGNVPCSPCPARSHSPDPAAPVCPCLQGFYRASSDPPEAPCTGPPSAPRELWFEVQGS--ALMLHWRLPQELGGRGDLLFNVVCKECGGHGEPSSGG--MCRRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQ--------------------------------AAAINVSTSHEVPSAVPVMHQVSRAANSITVSWPQPEQTNGNILDYQLRYYDQAEDESH-SFTMTSETNTATVTRLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPEKLSLVIGSILGALAFLLLAAITVLAVIFQR-----KRRGTGYTEQLQQYSSPGL----------------------GVKYYIDPSTYDDPCQAIRELAREVDPTYIKIEEVIGAGSFGEVRRGRLQPRG--RREQAVAIQALWAGGAESLKMTFLGRAALLGQFQHPNILRLEGVVTKSRPVMVLTELMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRALSARSVLVNSHLVCKVARLGHS---------------PQGSSSLLRWAAPEVITHGKYTTSSDVWSFGILMWEVMSYGERPYWDMNEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAEGGSGDRPSQALLNPVALDFPCLDSPQAWLSAIGLECYQDNFSKFGLSTFSDVAQLSLEDLPGLGITLAGHQKKLLHNIQLLQQHLRQPGSVEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15197-1", "uniprot_id": "EPHB6_HUMAN", "id": "O15197-1", "name": "Ephrin type-B receptor 6", "aln": "-------------------------------------------------MATEGAAQLGNR-VAGMVCSLWVLLLVSSVLALEEVLLDTTGETSEIGWLTYPPG------GWDEVSVLDDQR-RLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTCRETFTLYYRQAEEPD------SPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSAAWAVGPHGAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSFASFPETQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPGYQPARGDKACQACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEAPCTGPPSAPQELWFEVQGS--ALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTCHRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQ--------------------------------AAAINVSTSHEVPSAVPVVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESH-SFTLTSETNTATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLPQGELSSQLPERLSLVIGSILGALAFLLLAAITVLAVVFQR-----KRRGTGYTEQLQQYSSPGL----------------------GVKYYIDPSTYEDPCQAIRELAREVDPAYIKIEEVIGTGSFGEVRQGRLQPRG--RREQTVAIQALWAGGAESLQMTFLGRAAVLGQFQHPNILRLEGVVTKSRPLMVLTEFMELGPLDSFLRQREGQFSSLQLVAMQRGVAAAMQYLSSFAFVHRSLSAHSVLVNSHLVCKVARLGHS---------------PQGPSCLLRWAAPEVIAHGKHTTSSDVWSFGILMWEVMSYGERPYWDMSEQEVLNAIEQEFRLPPPPGCPPGLHLLMLDTWQKDRARRPHFDQLVAAFDKMIRKPDTLQAGGDPGERPSQALLTPVALDFPCLDSPQAWLSAIGLECYQDNFSKFGLCTFSDVAQLSLEDLPALGITLAGHQKKLLHHIQLLQQHLRQQGSVEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BKS8-1", "uniprot_id": "A0A8M2BKS8_DANRE", "id": "A0A8M2BKS8-1", "name": "receptor protein-tyrosine kinase", "aln": "--------------------------------------------------------------MEMWRIFLSVSLVVQHSSAEEVMLLDTSESTAELGWTTYPDT------GWDEVSVLDDKG-RLMRTFEVCNVNQNP--RLQDNWLATPFLYRQSAPRIFVTLRFSVRDCASLRSPSPTCRETLTLYYKQADSQRELERTWAAEASSGETREGWVKIDTIAADKSFSRVEPSLP-----------HQYKSENARRINVKTRSFAPLTRKGFVLAIVDSGACVSLMGVSIFYRRCPATSRFLAFYPATPS-GAEPTSLVPVTGTCVPHSQSQ--------GGTAPRMHCNTEGEWLVPVGGCTCDAGYEPNHNGSACLVCPIGSYKAVAGSVSCTECPANSRTSSEGAKVCECRSGYYRAPADANTTACTSSPSAPLALSWEYESSEGGVSLRWRPPADMGGRTDVWYGVVCRICP---SATSTPPSMCSWCGETVTYSPSQNGLKQTRVTLKNLLTRVTYLIQVQAMNEVSALSPFPPQ--------------------------------FASINFTTSQSVPSEVPMLHQLSRVQDSITLSWPQPDRPNGDILEYQLRYYDKGSDEDS-ALSMYSETNTVTVTGLIPGSIYAFQIRARNERGFGPYSHTIYFSTLASEGQSKQIQNRLPLMIGSVMGGAAFLLVVIAIIIVFVFRS-----KRRESPYSDRLQRYISNRG----------------------GVKYYVDPSTYEDPSEAVKEFAREIDPAHLKIEEVIGAAQFGEVSRGRYRPIG--RREALVAVKTLRWGVTEREKNVFLSEAGVLGQFDHPNVLKLEGVITRTPPERIITEFMENGPLDAFLRENEDQFSVLQLVGMVRGVGAGMRYLSERNFVHRDLAARNVLVNSNLVCKVSDFGLSRLMRGLDHNMPTYTASLGSKIPVRWTAPEAFQHRKFSSASDVWSFGILMWEVMSYGERPYWDMSNQEVMKAVVDQYRLPAPNGCPPALHSLMLQCWQADRQDRPGFDSLLSSLDRLIRHPASLKAEHS---RPTQPLLSPTPTDLSSVNTVGDWLTVLKMDRYKDAFERAQYHSLESVSMLTMQDVQALGVNLLGHQRKIVNAAKQLRTHLTQ-GHVEV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V4E5-1", "uniprot_id": "Q9V4E5_DROME", "id": "Q9V4E5-1", "name": "receptor protein-tyrosine kinase", "aln": "MKMVGCHPNDKKVKYDGIKSKTSSVTILTSVLNDAISALKSAFYKNQAPISEQNRSQIVSRMSLLRTILLIIISIHFKLAHADQVVLLDTTREATLEWTRYPYGPQAQTPGWVEESFTDFVKGINWRSYVVCDVAYHN----VNNWLWSPFIDRGSANRLYIEIQFTIRDCSLFPGNALSCKETFSLLFYEFDAAT--------REPPPWQTDSYRLIARIAAGE---------------------GRFNQNSDVDINTEVKSIA-VNKKGVYFAFRDQGACISVLAVKVYYITCPAVTENFAHFNETPT-GREITIIEKQNGTCVDNAEPY----------ETPTYLCKGDGKWTILTGGCRCKAGYEPNYTNKTCTECPLGTFKSPE-VTKCTPCPPNSNASKTGSPFCKCASGFYRHPNDGRHMPCYSPPAAPTNLTLLFVDQT-SAIISWSAPAKNE-------SFSSETNSKIYHSDIVYKIKCNICSPNVVYNPSTDTFNETKITLTNLEPVTTYTVQIHAINSVSHINEFKRHSNESSLVAVSDIVFSNTSLLNIPLDLNEVKTGQAEIVFTTESVLLSTVFNLRILAITNKDADLEWDKPVQSDFPLEFYEVRWFPKVELDAINKSALNTKETKAHIVGLLENTEYGFQVRCKTNNGFGSYSNMIYAQTLQSVGSVYDDSVQIRFIAGAIVTGVLFLVIFIIATVYFMRSKHQDDLDKKSTNHLPLPLDYASNEVNSMDTTPIVKKLHLNVTTPLFGNSRSYVDPHTYEDPNQAIREFAREIDANYITIEAIIGGGEFGDVCRGRLKIPPNFVQDIDVAIKTLKPGSSEKARCDFLTEASIMGQFDHPNVIYLQGVVTRSNPVMIITEYMENGSLDTFLRVNDGKFQTLQLIVMLRGIASGMSYLSDMNYVHRDLAARNVLVNAQLICKIADFGLSREIEN----ASDAYTTRGGKIPVRWTAPEAIAFRKFTSASDVWSYGVVLWEVMSYGERPYWNWSNQDVIKSIEKGYRLPAPMDCPEALYQLMLDCWQKQRTHRPTFASIVSTLDNLARQPQSLLTTRPSPESDGNHILD-GQRGQNIFISTDLWLEHIKMSRYCHHFKEANLINAQQISRLTAQQLSDMGITLVGHQKKILHQARQLDTII--------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : : ::* : : : * ** ** * *. * *:: .*.* :*** : *: * .* * .: ::*::* *: : . :*:**::* : : : . . : : ***.: .. :*.: :*:. :.::*. .*: * ***::::.* :: **:. . :* : * : * : : **** :::. .* *: :*.* : .*** *..*::* .. * ** * :*: . *: **..*.:.. .: .* * .*:** . * .* ..*:** * .. . : * * . .. .. . * * * :.* :.:::: : .* . ..* ::::*:* ** :. : * * .:*. : * * :: :: . .. :.* :* :.: : *::*:: : . : :: :: ... :. * . *.**:*.:. *.*.*. :* .** . : :: :: *::: . **:: : .: .:: : : * * . : *:** **:** :*::*:***:*. ::.** :** ..**:* :** : :: **:::* * :* : ** .*.::***:***:: *:**:*:: * ::** ** *.**:*** .:.:*. ***: * **:.:.* ***. :*** *:*:.****::*:**:: :* * . * . :**:***.: . *.:::*****:*:::************: .:*:*:::: . :***.* .** .*: ***: ** :* ** * .:::::*.: *:* :* : : :* . . : ** : :. * . *.. . ..:: *: ::: :*:.* ***:*::: : * : ", "identical_positions": 251, "similar_positions": 334, "identity": "21.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-54", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZW82-1", "uniprot_id": "D3ZW82_RAT", "id": "D3ZW82-1", "name": "", "aln": "MELPSIPHLFLPLALLTGLCSPFNLDEHHPRLFTGPPEAEFGYSVLQHVGGGQRWMLVGAPWDGPSGDRKGDVYRCSIGGFHSAPCTKGHLGDYQLGNSSQPAVNMHLGMSLLETDADGGFMACAPLWSRACGSSVFSSGICAHVDASFRLQGSLAPTAQRCPTYMDVVIVLDGSNSIYPWSEVQTFLRRLVGRLFIDPEQIQVGLVQYGENPVHEWSLGDFRTKEEVVRAARNLSRREGRETRTAQAIMVACTEGFSESRGGRPEAARLLVVVTDGESHDGEELPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSFLREIRAIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSRGENESSFGLEMSEIGFSIHRLQDGILFGMVGAYDWGGSVLWLEEGRRLFPPRTALEDEFPPALQNHAAYLGYSVSSMLLPGGRRLFLSGAPRFRHRGKVIAFQLKKDGVVKVTQSLQGDQIGSYFGSELCPLDTDMDGITNILLVAAPMFLGPQNKETGRIYVYVVGQQNLLMLQGTLQPD-RSQDSRFGFAMAALPDLNHDGFSDVAVGAPLEDGHQGALYLYHGTQTGIRPHPTQRIAAGSMPQALRYFGRSVDGRLDLDGDDLVDVAVGAHGAAILFSSQPIIHLIPTLDVMPPHISVVQKDCKRRGQEAACLTASLCFQVKSQTPGRWDRRFHIRFSASLDEWTAGARAAFDGSGQRLSPGQLRLSVGNVTCEQLHFHALDTSDYLRPVALTVTFALDNTTKPGPVLAEGSSTSIRKLIPFSKDCGPDNECITDLVLQADMDIRGSRKSPFVVQGGRQKVLVSVTLENKKENAYNTSLSLSFSRNLHLASLTPQRAKSVKVECAVPSPHARLCIVGHPVFQAGAKVSFLLEFEFSCTFLLSQVSVRLTASSSSLERNETLQDNTAQTSAYIRYEPHLMFSSESTLHRYEVHPYRALPVGPGPEFKTTLRVQNLGCHVVSGLVVSALLPAVAHGGNYFLSLSQVISGNAS---CTVQN------LTDPPGFPVHPEELQHTSRLNGSNTRCQAVRCHLGLLPKGTEISVGLLRLVHNEFFRRAKFKSVTVVSTFKLGTEKGSVLLLNEASQWRESHLEVIQTLPTLISLWILVGSVLGGLLLLALLVFCLWKLGFFTRKKIPKEEQSEGKLEQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q6R1-1", "uniprot_id": "E9Q6R1_MOUSE", "id": "E9Q6R1-1", "name": "", "aln": "MESLSIPHLLLPLALLTGLCSSFNLDEHHPRLFTGPPEAEFGYSVLQHVGGGQRWMLVGAPWDGPSGDRRGDVYRCSIGGFHSAPCTKGHLGDYQLGNSSQPAVNMHLGMSLLETDADGGFMACAPLWSRACGSSVFSSGICARVDASFRPQGSLAPTAQRCPTYMDVVIVLDGSNSIYPWSEVQTFLRRLVGRLFIDPEQIQVGLVQYGENPVHEWSLGDFRTKEEVVRAARNLSRREGRETRTAQAIMVACTEGFSQSRGGRPEAARLLVVVTDGESHDGEELPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSFLREIRAIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSRGENESSFGLEMSEIGFSIHRLQDGILFGMVGAYDWGGSVLWLEEGRRLFPPQAALEDEFPPALQNHAAYLGYSVSSMLLPGGRRLFLSGAPRFRHRGKVIAFQLKKDGVVRVAQSLQGDQIGSYFGSELCPLDTDKDGITNILLVAAPMFLGPQNKETGRVYVYMVGQQNLLMLQGTLQPD-RSQDSRFGFAMAALPDLNHDGFTDVAVGAPLEDGHRGALYLYHGTQTGIRPHPTQRIAAVSMPQALRYFGRSVDGRLDLDGDDLVDVAVGAHGAAVLFSSQPIIHLIPTLDVMPPHISVVQKDCKRRGQEAACLTAALCFQVVSQTPGRWDRRFYIRFSASLDEWTAGARAVFDGSGQRLSPRQLQLSVGNVTCEQLHFHALDTSDYLRPVALTVTFALDNTTKPGPVLAEGSSTTIRKLIPFSKDCGPDNECVTDLVLQADMDIRGSRKSPFVVQGGRQKVLVSATLENKKENAYNTSLSLSFSRNLHLASLTPQKAKSVKVECAVPSPHTRLCTVGHPVFQTGAKVSFLLEFEFSCTFLLSQVFVRLTASSSSLEMNETLQDNTAQTSAYIRYEPHLVFSSESTLHRYEVHPYRTLPMGPGPEFKTTLRVQNLGCHVVSGLVISALLPAVAHGGNYFLSLSQVISGNAS---CTVQN------LTEPPGFPVHPEELQHASRLNGSNSRCQVVRCHLGLLAKGTEISVRLLRLVHNEFFRRAKFKSVTVVSTFKLGTEEGSVLLLNEASRSSESHLEVIQTHPTLISLWILVGSVLGGLLLLALLVFCLWKLGFFTRKKIPKEEESEEKLEQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75578-1", "uniprot_id": "ITA10_HUMAN", "id": "O75578-1", "name": "Integrin alpha-10", "aln": "MELPFVTHLFLPLVFLTGLCSPFNLDEHHPRLFPGPPEAEFGYSVLQHVGGGQRWMLVGAPWDGPSGDRRGDVYRCPVGGAHNAPCAKGHLGDYQLGNSSHPAVNMHLGMSLLETDGDGGFMACAPLWSRACGSSVFSSGICARVDASFQPQGSLAPTAQRCPTYMDVVIVLDGSNSIYPWSEVQTFLRRLVGKLFIDPEQIQVGLVQYGESPVHEWSLGDFRTKEEVVRAAKNLSRREGRETKTAQAIMVACTEGFSQSHGGRPEAARLLVVVTDGESHDGEELPAALKACEAGRVTRYGIAVLGHYLRRQRDPSSFLREIRTIASDPDERFFFNVTDEAALTDIVDALGDRIFGLEGSHAENESSFGLEMSQIGFSTHRLKDGILFGMVGAYDWGGSVLWLEGGHRLFPPRMALEDEFPPALQNHAAYLGYSVSSMLLRGGRRLFLSGAPRFRHRGKVIAFQLKKDGAVRVAQSLQGEQIGSYFGSELCPLDTDRDGTTDVLLVAAPMFLGPQNKETGRVYVYLVGQQSLLTLQGTLQPE-PPQDARFGFAMGALPDLNQDGFADVAVGAPLEDGHQGALYLYHGTQSGVRPHPAQRIAAASMPHALSYFGRSVDGRLDLDGDDLVDVAVGAQGAAILLSSRPIVHLTPSLEVTPQAISVVQRDCRRRGQEAVCLTAALCFQVTSRTPGRWDHQFYMRFTASLDEWTAGARAAFDGSGQRLSPRRLRLSVGNVTCEQLHFHVLDTSDYLRPVALTVTFALDNTTKPGPVLNEGSPTSIQKLVPFSKDCGPDNECVTDLVLQVNMDIRGSRKAPFVVRGGRRKVLVSTTLENRKENAYNTSLSLIFSRNLHLASLTPQRESPIKVECAAPSAHARLCSVGHPVFQTGAKVTFLLEFEFSCSSLLSQVFVKLTASSDSLERNGTLQDNTAQTSAYIQYEPHLLFSSESTLHRYEVHPYGTLPVGPGPEFKTTLRVQNLGCYVVSGLIISALLPAVAHGGNYFLSLSQVITNNAS---CIVQN------LTEPPGPPVHPEELQHTNRLNGSNTQCQVVRCHLGQLAKGTEVSVGLLRLVHNEFFRRAKFKSLTVVSTFELGTEEGSVLQLTEASRWSESLLEVVQTRPILISLWILIGSVLGGLLLLALLVFCLWKLGFFAHKKIPEEEKREEKLEQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RMK2-1", "uniprot_id": "A0A8M1RMK2_DANRE", "id": "A0A8M1RMK2-1", "name": "", "aln": "MEIHKYLLLFKITILLKGLCECFNIDVKRPRIFSGPEDALFGFSVLQHDDNGEKLLLVGAPWDGPQNNRKGDIYKCIVE-DENSNCSKVNLGENAFQNVSRNLKNSHLGMTLTPTDSDG-FLACAPLWSQECGTSLFSTGICASVTSDMEPNDVIAPTAQRCTTYMDIVIVLDGSNSIYPWYEVQNFLSNILSKFHISPEQMQVGVLQYGEISVHEWSLRDYQTTADVVEAAKNISRQEGRETRTAYAIQMACTEAFSPDRGAREGATKVMIVVTDGESHDGEDLPEALIECEKRNITRYAIAVLGHYIRRQQDPETFINEIKYIASDPDEKYFFNVTDEAALNDIVDALGDRIFSLEGTLGYNESAFLMEMSQIGFSTHILDDGILFGMVGAYDWEGGILKESKEGQLMPPREAFEKEFPLELKNHAAYLGYTVSSVVVGNWRRLYVAGAPRFKHKGKVILFDLTPEGDVIITQALNGEQIGSYFGSEVCVVDVDQDGITDILLIAAPMFLGAGNKETGKVYVFCLDG-DGFAPNGTLHSQQKAQDARFGYAMAVAPDLNHDGYTDLLVGAPLEDDHQGALYIYHGDEYYIIPQYKQRISGSSLSTGLRYFGRSLSALLDLDGDELLDLAVGAQGSAVLLKSRSIVQINVSLSFQPHSINVIQKNCLRAGRDSACLNATVCFLALSRSPGSRGTYFDMQVGAMLDDRKISARALFDSNSQRQTLMSISVRVGETKCYILPFHVFDTADYIRPISFTLRFKIN-DTESGPVLDEGWPTTHKKSIPFFKDCGEDDVCVTDLVLQAHMDISGTRQVPYVIRSPRRRLAVEVQLQNKLENAYNTSLTLHYSKNLHFSTLSIREDAQFKIECTALGSNSHSCNVSYPVFRSQSKVNFMLEFEFSCTSLISKVQMRLIASSDSVEREGTLSDNTVQLQSIVQYEPDLFITSDSNLNRYEVHPTRTASEGTGPEFYTHFRVQNLGCYAVSNLELSVSLPAVASGDRVFAAVVDAFSHNASGVNCTIVNDISKLKSSQRDVRPLHPEDMKKTELMNCSSSWCVEVMCHIQQLLKGQTALIRITRRIHDSFFRQAKFKAVTIVGSYQLSARESNLITMGNAALLRETTLEVLKGRSIPISLWILIGSIIGGLLLLALLVFILWKLGFFTRKQRKDKDENDDN---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *: :*.***. **:* ::**:*.** :* **:***** ..*:: :*********..:*:**:*:* : ..: *:* :**: : * *: * ****:* **.** *:*******: **:*:**:**** * :.:. :. :*******.****:************* ***.** .::.::.*.***:***::**** .****** *::*. :**.**:*:**:*****:** ** :****.** .:*.* *:::::***********:** ** ** .:***.*******:***:**.:*:.**: *******::**********.***********.***: . ***:* :***:**** * *.************* *.:* . :*:**: *:*.*** *:********:***::: . ***:::*****:*:**** *:*. :* * ::*:*:*:*********:* :*.* ** *::**:*******. *****::**: :. . : :***:.: .**:***:**.. ****:**::*: *******.*:****:*** : : *: ***:. *:. .* *****:.. ******:*:*:****:*:*:*:.*:.*::: :*.. * *.*:*::* * *:::.**.*::** . *::** . * ::. * **: . .*** **...** : : : **:..* * **.:**:**:**:::*: * :: *:.**** ** .*: :* :** **** *: *:******..*** *:*: *:*::. *::: *.. *:*: ********:* :*:***:::*: :. .*:**:. ..::: * *.:***:: :**.*:*******: *:*:* ::* ***.*:* : **.***.* .: ::***.*.::*:*.*:****** : . *.**** * :*******:.**.* :*. ***** *.. * :: :.:: *** * : * :: *:***:::::. :* *.: * * **: * ** : : * :*:.***:****::*:*.:::*.:.:..:: : :*: *: ***:: . ******:**::*********** *******::*: .::: : : ", "identical_positions": 591, "similar_positions": 364, "identity": "50.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q10586-1", "uniprot_id": "DBP_HUMAN", "id": "Q10586-1", "name": "D site-binding protein", "aln": "-MARPVSDRTPAPLLLGGP---------AGTPPGGGALLG---LRSLLQGTSKPKEPASCLLKEKERKAALPAATTPGPGLETAGPADAPAGAVVGGGSPRGRPGPVPAPGLLAPLLWERTLPFG----DVEYVDLDAFLLEHGLPPSP----------PPPGGPSPEPSPARTPAPSPGPGSCGSASPRSSPGHAP---------ARAALGTAS---GHRAG-LTSRDTPS-------PVDPDT--VEVLMTFEPDPADLALSSIPGHETFDPRRHRFSEEELKPQPIMKKARKIQVPEEQKDEKYWSRRYKNNEAAKRSRDARRLKENQISVRAAFLEKENALLRQEVVAVRQELSHYRAVLSRYQAQHGAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60925-1", "uniprot_id": "DBP_MOUSE", "id": "Q60925-1", "name": "D site-binding protein", "aln": "-MARPLSDRTPGPLLLGGP---------AGAPPGGGALLG---LRSLLQGNSKPKEPASCLLKEKERKATLPSAPVPGPGLETAGPADAPSGAVSGGGSPRGRSGPVAGPSLFAPLLWERTLPFG----DVEYVDLDAFLLEHGLPPSP----------PPPGGLSPAPSPARTPAPSPGPGSCSSSSPRSSPGHAP---------ARATLGAAG---GHRAG-LTSRDTPS-------PVDPDT--VEVLMTFEPDPADLALSSIPGHETFDPRRHRFSEEELKPQPIMKKARKVQVPEEQKDEKYWSRRYKNNEAAKRSRDARRLKENQISVRAAFLEKENALLRQEVVAVRQELSHYRAVLSRYQAQHGTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AA52Z2W8-1", "uniprot_id": "A0AA52Z2W8_DANRE", "id": "A0AA52Z2W8-1", "name": "", "aln": "MMARPLSQLLPPDLPSAGASPQFGNSSQAGVTHNGGHLNSTGNLKSLLQLPVKCDQRVKDCGEMKGKERLDIDEDSLGRCPLRNGCSNGLVSDSNGAGTGSFSNNSNNNNSFLGPLLWERTLPCDGGLFQLQYMDLEEFLTENGMSSMHNTSNSTSAQIPSQSSQSAVPNQGSQCLPTSPPHCSSSSSPTSATASSPSLLGLDMHTPQSMMGSTDCLHGTPPGSLEPTPSPSSTTCPPLPTPPATNCNELLAPFDPDPADVALSSVPGQEAFDPRRHHFSDEDLKPQPMIKKARKMLVPEDLKDEKYWSRRCKNNEAAKRSRDARRLKENQISVRAAFLERENAALRQEVADMRKELGRCRNILNKYESHHLDQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****:*: * * .*. **.. .** * . *:**** * .: .. : * :: * * ::. . *.*: .. .::.********* . :::*:**: ** *:*:.. *. .. *. *. . *:. * ...*:** *:.. :* .:: :*::. * .* * . :** *. * * *:* .*:*****:****:**:*:******:**:*:*****::*****: ***: ********* ****************************:*** *****. :*:**.: * :*.:*:::* ", "identical_positions": 148, "similar_positions": 91, "identity": "39.57%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-60", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60636-1", "uniprot_id": "TSN2_HUMAN", "id": "O60636-1", "name": "Tetraspanin-2", "aln": "MGRFRGGLRCIKYLLLGFNLLFWLAGSAVIAFGLWFRFGGAIKELSSEDKSPEYFYVGLYVLVGAGALMMAVGFFGCCGAMRESQCVLGSFFTCLLVIFAAEVTTGVFAFIGKGVAIRHVQTMYEEAYNDYLKDRGKGNGTLITFHSTFQCCGKESSEQVQPTCPKELLGHKNCIDEIETIISVKLQLIGIVGIGIAGLTIFGMIFSMVLCCAIRNSRDVI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QBY8-1", "uniprot_id": "E9QBY8_DANRE", "id": "E9QBY8-1", "name": "Tetraspanin", "aln": "MGKVEGGMKCVKFLLFIFNFIFWLMGSLVLAVGLWLRLDPNTVSLLGED-GPDTFFIGVYILIAAGGLVMLVGFFGCCGAVRESQCLLGLFFACLLVIFGAEVAAGVFGFINKDKIIQEIRHFYDESAGN-----NNNNATVQSYHTVLSCCG---SSTVTPSSCKNMVFNQTCDVAIEEFFNSKLFIVGYVGIGIAGVMIIGMIFSMVLCCAIRNSREVI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:..**::*:*:**: **::*** ** *:*.***:*:. .* .** .*: *::*:*:*:.**.*:* *********:*****:** **:******.***::***.**.*. *:.:: :*:*: .: .:.*.*: ::*:.:.*** *. * *:. *::: ::.* ** ::. ** ::* *******: *:****************:**", "identical_positions": 111, "similar_positions": 73, "identity": "50.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-64", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZEN1-1", "uniprot_id": "D3ZEN1_RAT", "id": "D3ZEN1-1", "name": "Ephrin-A4", "aln": "MRLLPLLRTVLWAALLG--SRLRGCSSLRHSIYWNSTNPRLLRGDAVVELGLNDYLDIFCPHYESPGPP-EGPETFALYIVDWSGYEACKAEGANAFQRWNCTLPFAPFVPVRFSEKIQRFTPFPLGFEFLPGETYYYISVPTPESPGQ-CLRLQVSVCCKEDRS--ESAHPVGSPGESGTSGWRGGHAPSPLSLLLLLLLPILRLLRVL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08542-1", "uniprot_id": "EFNA4_MOUSE", "id": "O08542-1", "name": "Ephrin-A4", "aln": "MRLLPLLRTVLWAALLG--SRLPGCSSLRHPIYWNSSNPRLLRGDAVVELGFNDYLDIFCPHYESPGPP-EGPETFALYMVDWSGYEACTAEGANAFQRWNCSMPFAPFSPVRFSEKIQRYTPFPLGFEFLPGETYYYISVPTPESPGR-CLRLQVSVCCKESGSSHESAHPVGSPGESGTSGWRGGHAPSPLCLLLLLLLPILRLLRVL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52798-1", "uniprot_id": "EFNA4_HUMAN", "id": "P52798-1", "name": "Ephrin-A4", "aln": "MRLLPLLRTVLWAAFLG--SPLRGGSSLRHVVYWNSSNPRLLRGDAVVELGLNDYLDIVCPHYEGPGPP-EGPETFALYMVDWPGYESCQAEGPRAYKRWVCSLPFG---HVQFSEKIQRFTPFSLGFEFLPGETYYYISVPTPESSGQ-CLRLQVSVCCKERKS--ESAHPVGSPGESGTSGWRGGDTPSPLCLLLLLLLLILRLLRIL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q7R4-1", "uniprot_id": "A0A8M1Q7R4_DANRE", "id": "A0A8M1Q7R4-1", "name": "Ephrin-A4", "aln": "MNTPRCSGVCAMMRLLALFIHVLSTTAKRHVVYWNSTNTRLTGDDYSVQVNLSDYLDILCPHYPGDHPSGASVETLALYLVAESQFRGCVDT-KEAIKRWECNQPFAPFGPVRFSEKIQRFTPFSLGFEFLPGHHYYYSSLSTDDGPPLPCMKLRVTVCCP--------PTTAGSSRQEATETPSHSTTVQNMTLTQLFLLLIPFLLSYFL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . :*. : . :: ** :****:*.** .* *::.:.*****.**** . *. . **:***:* . :..* .* :** *. **. *:*******:***.********. *** *:.* :.. *::*:*:*** . ..**. :..*. . : . : * *:** * ** : ", "identical_positions": 76, "similar_positions": 58, "identity": "36.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-73", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C0Q4-1", "uniprot_id": "NEK11_MOUSE", "id": "Q8C0Q4-1", "name": "Serine/threonine-protein kinase Nek11", "aln": "MLKFQETAKCVGRR-PTVIPMYPTALIARRYVLQQKLGSGSFGTVYLVSDKKAKPGEELKVLKEISVGELNPNETVQANVEAQLLSRLHHPAIVRFHASFMEQETFCIITEYCEGRDLDYRIQEYKEAGKVFAENQIVEWFIQLLLGVDYMHERRILHRDLKSKNIFLKNNLLKIGDFGVSRLLMGSCELATTLTGTPHYMSPEALKHQGYDAKSDIWSLACILYEMCCLDHAFAGSSFLSVVLNIVEGKTPSLPDRYPRELNTIMERMLNKSPSLRPSAADILKAPYMEEQLQLLMCKYPEMTLEDKNSVCQKEAAHTINAVQKKLHLQTLQALSDTQKTTPRERMWLRKLQAADERARRLKKIAEENYKENDKRMQALRSRNVGSVHAHVLHEL------------------------------------DERTLESLPEPQSLPCLDLDELEPSLEDTIVDLG-----HYEIPEDPLVAEQYY-SDVFDSCSEDSEEQEEEMIFSEAGGDTKEEESPSVYRTNQQDSDTAALVGCLEHVLGYTSLDTKTITNAVTDMSPGPMVFNSAVARTKMKRMKESAVQKLGMETFEEVYDYLKRARHQNAREAEIWEHLETVVPRASDCFEVDQLLYFEELLLTMEG--KEPSLQNLPCEAAQKKPVKGTHFCDNP----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NG66-1", "uniprot_id": "NEK11_HUMAN", "id": "Q8NG66-1", "name": "Serine/threonine-protein kinase Nek11", "aln": "MLKFQEAAKCVSG--STAISTYPKTLIARRYVLQQKLGSGSFGTVYLVSDKKAKRGEELKVLKEISVGELNPNETVQANLEAQLLSKLDHPAIVKFHASFVEQDNFCIITEYCEGRDLDDKIQEYKQAGKIFPENQIIEWFIQLLLGVDYMHERRILHRDLKSKNVFLKNNLLKIGDFGVSRLLMGSCDLATTLTGTPHYMSPEALKHQGYDTKSDIWSLACILYEMCCMNHAFAGSNFLSIVLKIVEGDTPSLPERYPKELNAIMESMLNKNPSLRPSAIEILKIPYLDEQLQNLMCRYSEMTLEDKNLDCQKEAAHIINAMQKRIHLQTLRALSEVQKMTPRERMRLRKLQAADEKARKLKKIVEEKYEENSKRMQELRSRNFQQLSVDVLHEKTHLKGMEEKEEQPEGRLSCSPQDEDEERWQGREEESDEPTLENLPESQPIPSMDLHELESIVEDATSDLG-----YHEIPEDPLVAEEYY-ADAFDSYCEESDEEEEEIALERPEKEIRNEGSQPAYRTNQQDSDIEALARCLENVLGCTSLDTKTITTMAEDMSPGPPIFNSVMARTKMKRMRESAMQKLGTEVFEEVYNYLKRARHQNASEAEIRECLEKVVPQASDCFEVDQLLYFEEQLLITMG--KEPTLQNHL----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA54FLJ5-1", "uniprot_id": "A0AA54FLJ5_DANRE", "id": "A0AA54FLJ5-1", "name": "Serine/threonine-protein kinase Nek11", "aln": "MPRFRERPGQTNCHPESETSPDLCSLIANRYIIQQRLGKGSFGTVYLVKDTKAVAEERLKVLKEIPVGDLKPNETVHATQEAQLLSQLSHPAILKFYSSFLERDAFCIITEFCEDKDLDCKLEELKHTGKTLSEPQVCEWLCQLLLGVHYIHQRRILHRDLKAKNIFLRKNIVKIGDFGVSCFLMGSCDLATTFTGTPYYMSPEALSHKGYDSKSDIWSLGCILYEMCCLAHAFEAQNFLAVVLRIVEGPTPSLPETYSRQLNSLMQSMLEKDSSHRISAADALRNRFIEESLQSMKHKFSILSLRDKSIGGERDASQILRALQKKVHLQTLQDRSEVQKMSPRERMRLRKLQAADEKARKLKQIVEEKYQENHLRMQEYKSKNFHKISVDFLKVQ------------------------------------PEEAVNQTQVIQSESPKENSEMTGNVSHLTDKMCTTVSKEHAIPEDPQAAEAFYFVDEFESCSEEDSDGEE-----DPEDNLPTDPS---CQTCGQDGDLEALIRHMENVLVGDSDGAETENEKPQLGFLGVGSINMSMAEGRIQRMRESVCRRLGEEVFLKVYDYLKQARQKQESEESIRQTLIELVEKPSDCFEVDQLLYYEEILLAAQENTKSPESGQVSWKSQRNERIYILQHLHAVLLTEISISGL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :*:* . .. : . :***.**::**:**.*********.*.** *.*******.**:*:*****:*. ******:* ****::*::**:*:: ******:**.:*** :::* *.:** :.* *: **: ******.*:*:*********:**:**::*::******** :*****:****:****:*******.*:***:*******.********: *** ...**::**.**** *****: *.::**::*: **:*..* * ** : *: :::*.** : ::. ::*.**. :::*:: :.*:**::*****: *:.** :***** *********:**:**:*.**:*:** *** :*:*. .: ...*: * :::. *. . : *: :.. .: : ***** .** :* * *:* .*:..: ** . : : * :* **.* ** :*:** * .::* . * :* :*. :::**:**. ::** *.* :**:***:**::: * .* : * :* :.***********:** ** *.* : ", "identical_positions": 288, "similar_positions": 176, "identity": "42.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-79", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P06307-1", "uniprot_id": "CCKN_HUMAN", "id": "P06307-1", "name": "Cholecystokinin", "aln": "MNSGVCLCVLMAVLAAG-ALTQPVPPAD--------PAGSGLQRAEEAPRRQLRVSQR--TDGESRAHLGALLARYIQQARKAPSGRMSIVKNLQNLDPSHRISDRDYMGWMDFGRRSAEEYEYPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09240-1", "uniprot_id": "CCKN_MOUSE", "id": "P09240-1", "name": "Cholecystokinin", "aln": "MKSGVCLCVVMAVLAAG-ALAQPVVPAE--------ATDPVEQRAQEAPRRQLRAVLR--TDGEPRARLGALLARYIQQVRKAPSGRMSVLKNLQSLDPSHRISDRDYMGWMDFGRRSAEDYEYPS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9QEB3-1", "uniprot_id": "E9QEB3_DANRE", "id": "E9QEB3-1", "name": "", "aln": "MNAGLCVCALLAALSTSSCLSLPVHSEDGVQSNVGSATGHTRHTRAAPPAGQINLLTKPEDDEEPRSSLTELLARIISTKG---SYRRSPAANSRTMGASHRIKDRDYLGWMDFGRRSAEEYEYSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::*:*:*.::*.*::. .*: ** . : .:. : .* *:. : * *.*: * **** *. * * * * :.:..****.****:***********:***.*", "identical_positions": 47, "similar_positions": 35, "identity": "37.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100922-89", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWM3-1", "uniprot_id": "D3ZWM3_RAT", "id": "D3ZWM3-1", "name": "", "aln": "----MDSYFPAKNSTLAVNMNETLS--ASHGFNSTSDPPP----MSITRLFPALLECFGIVLCGYIAGRANVITSTQAKGLGNFVSRFALPALLFKNMVVLNFANVDWAFLYSILIGKASVFFVVCVLTLLVASPESRFSKAGLFPIFATQSNDFALGYPIVEALYQTTYPEYLQYIYLVAPISLMMLNPIGFIFCEIQKSKDTRNASQ-----------------------NKAKIVGLGFLRVLQNPIVFMVFVGIAFNFILDKKIPVYMENFLDGLANSFSGSALFYLGLTMVG-KIRRLKKSAFVALIVLITAKLLVLPLLCREMVEVLDKGN-SVVNHTSLSNYAFLYGVFPVAPGVAIFATQFNMEVEIITSGMVISTFVSAPIMYVSAWLLTFPTMDAKPLAYAIQNVSFDISIISLVSLIWSLSVLLLSKKYKQLPHMLTANLLIAQTIVCAGMVIWNFVKEKN-FVGQILVFVLLYSSLYSTYLWTGLLAVSLFLLKKRESVQIP--VGLIIISGWGIPALLVGVLLITG--KHNGDSVDSAFFYGKEQMITTAVTLFCSILIAG-------------------------------------VSLMCMNRTTQAGHYEGFGQSQSHKPVEPGSTAFEESPAPTSEPELFPSSIPETGCCSCSLGNGELRCPSIQPGTNSSAS------------------------------------RPRPSSFEKTDQCVSRCDSQSCILAQEEEQ------------YLQSGDPQLTRHVLLCLLLIIGLFANLSSCLWWLFNHETGRLYVELQFFCAVFNFGQGFISFGIFGLDKHLIILPFKRRLEFLWN-NKETAEDRESPVSEEIKMTCQQFVHYHRDLCIRNIVRERRCGAKTSAGTFCGCDLVNWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYEFRDEYLFYRFLQKSPERSPPAGTVSNPPEESYKEIGHASPPSLSPKT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AWR3-1", "uniprot_id": "LYCHS_MOUSE", "id": "A2AWR3-1", "name": "Lysosomal cholesterol signaling protein", "aln": "----MDSYFSAKNSTLAGDMNATWP--ASHGFNATGDPPS----MSITRLFPALLECFGIVLCGYIAGRANIITSTQAKGLGNFVSRFALPALLFKNMVVLNFSNVDWAFLYSVLIGKASVFFIVCVLTLLVASPESRFSKAGLFPIFATQSNDFALGYPIVEALYQSTYPEYLQYIYLVAPISLMMLNPIGFIFCEIQKSKDTQNASQ-----------------------NKAKIVGLGFLRVLQNPIVFMVFVGIAFNFILDKKIPVYMENFLDGLANSFSGSALFYLGLTMVG-KIRRLKKSAFVVLTLLITAKLLVLPLLCREMVELLDKGD-SVVNHTSLSNYAFLYGVFPVAPGVAIFATQFNMEVEIITSGMVISTFVSAPIMYVSAWLLTFPTMDAKPLAYAIQNVSFDISIISLVSLIWSLSILLLSKKYKQLPHMLTANLLIAQTIVCAGMMIWNFVKEKN-FVGQILVFVLLYSSLYSTYLWTGLLAVSLFLLKKRESVQLP--VGIIIISGWGIPALLVGVLLITG--KHNGDSIDSAFFYGKEQMITTAVTLFCSILIAG-------------------------------------VSLMCMNRTTQAGHYEGFGQSQNHKPVEPGSTAFEENPAPTNEPELFPSSIPETSCCSCSLGNGELRCPSIEPVTNSSAS------------------------------------GPMPSSFEKTDHCVSRCDSQSCILAQEEEQ------------YLQSGDPQLTRHVLLCLLLIIGLFANLSSCLWWLFNHETGRLYVELQFFCAVFNFGQGFISFGIFGLDKHLIILPFKRRLEFLWN-NKEAAADRESPVSEEIKMTCQQFVHYHRDLCIRNIVRERRCGAKTSAGTFCGCDLVNWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYEFRDEYLFYRFLQKSPEQSPPARTLRDHQEESYKEIGHSSPPSVSPKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z3F1-1", "uniprot_id": "LYCHS_HUMAN", "id": "Q7Z3F1-1", "name": "Lysosomal cholesterol signaling protein", "aln": "----MNSNLPAENLTIAVNMTKTLPTAVTHGFNSTNDPPS----MSITRLFPALLECFGIVLCGYIAGRANVITSTQAKGLGNFVSRFALPALLFKNMVVLNFSNVDWSFLYSILIAKASVFFIVCVLTLLVASPDSRFSKAGLFPIFATQSNDFALGYPIVEALYQTTYPEYLQYIYLVAPISLMMLNPIGFIFCEIQKWKDTQNASQ-----------------------NKIKIVGLGLLRVLQNPIVFMVFIGIAFNFILDRKVPVYVENFLDGLGNSFSGSALFYLGLTMVG-KIKRLKKSAFVVLILLITAKLLVLPLLCREMVELLDKGD-SVVNHTSLSNYAFLYGVFPVAPGVAIFATQFNMEVEIITSGMVISTFVSAPIMYVSAWLLTFPTMDPKPLAYAIQNVSFDISIVSLISLIWSLAILLLSKKYKQLPHMLTTNLLIAQSIVCAGMMIWNFVKEKN-FVGQILVFVLLYSSLYSTYLWTGLLAISLFLLKKRERVQIP--VGIIIISGWGIPALLVGVLLITG--KHNGDSIDSAFFYGKEQMITTAVTLFCSILIAG-------------------------------------ISLMCMNQTAQAGSYEGFDQSQSHKVVEPGNTAFEESPAPVNEPELFTSSIPETSCCSCSMGNGELHCPSIEPIANTSTS------------------------------------EPVIPSFEKNNHCVSRCNSQSCILAQEEEQ------------YLQSGDQQLTRHVLLCLLLIIGLFANLSSCLWWLFNQEPGRLYVELQFFCAVFNFGQGFISFGIFGLDKHLIILPFKRRLEFLWN-NKDTAENRDSPVSEEIKMTCQQFIHYHRDLCIRNIVKERRCGAKTSAGTFCGCDLVSWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYEFRDEYLFYRFLQKSPEQSPPAINANTLQQERYKEIEHSSPPSHSPKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B2E6-1", "uniprot_id": "A0A8M3B2E6_DANRE", "id": "A0A8M3B2E6-1", "name": "", "aln": "----MEDLLGNVSVSSRDES------------GAPTVPPS----MSIDKLLPALLECFGIILCGYVAGRTNIILATQAKGLGSFVSKFALPALLFKNMVLLDFGDVIWPFFFSILVAKVTVFFFVCVLTLLVGNRESRYSKAGLFPIFATQSNDFALGFPIVEALYRSTHPEYLQYIYLVAPVSLMVLNPLGFMFCEVQRRKNGEPSQQ-----------------------SKLHVLGLVVLQVFKNPIVFMVMIGLVSHFLLCQKIPAFMEQFVDGLANSFGGAALFYLGLSMVG-QLKKLTRTTVVALILLITAKLLMMPLICRGMVEVLDNTNRSTLNHTSLSNYAFLYGVFPTAPSVAIYAAHYNMELEVVTSGMVVSTFLSAPIMYVSAWLLTIPWMDSAPLASALQNVSFDISIISLFALVWSLTVMILSRKYHRIPHIFTINLFVAQLLVCVGMIVWNFVVKQDSFVAQVLSFTLLYGSLYSTYIWPGLIVLSLLLMRS-EEVNFR--PGLTVITGWGLPFLAVSVLLLSG--HRMPDTIDSAFFYGTTQVMCTSVVLCVSIAVCG-------------------------------------VSLALLSRRTQD--YQNLVSGSLSGSEEDLRIPYN-APVQGSIEDTCTLGSTNTACQMC-------ECACALPQTRPDVT------------------------------------NTKEEVSIQTGQCGQECTSTHCLLVEEEEKET----------ERQNTDIQSTRHVLMCLILTVTSLANLCSCLWWLFNKDPGRLYLELQFFCVVANYGQGLISFAFFGLDKHLIISPFKKRLESVWQ-WWAQLVS-GSEVSEEIRLTCNQFLKYHKKQCIKDIVHKKRCGEKSSIQAFLGTDMVVWLQSVGLASDQGEAVLYGSRLLDGGVIQHITQQHAFEDQTLHYRFT------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PFK5-1", "uniprot_id": "M9PFK5_DROME", "id": "M9PFK5-1", "name": "", "aln": "MDSSMYYASQRIAASTEANVRVITSTMASSLANGTATPRADDGGVSMNNFYPALVQCFGIIICGYIAGRFKIISNAETKGLGTFVGTFALPSLIFLSLVELNWSAVNWSFLLAMLVSKAVVFFAVLIISLLVARPLN-YARGGLMAIFCTQSNDFAIGYPIVMALYKDVHPEYASYLYLMAPISLAILNPVGLVLMEISKIIKNKEDVTRNPPLCPETCPAEQMSKRNRCLGERSILVFNTLIALFFNPLLLMTLLGVAGGFLFPNGLPEMVSSTLRVLGQSFSATALFLLGLKIVGGTGSERKSIGFLLPGVLILVKILVLPLVIRQTVNIMQSGQ-NFNDTTELSTFGFLYGTFPAAPGAFVIATQYNMEVELVARSMVFCTFISAPLMFISAKMISLTNLKPLDYLHELDAFSFDISVAGAAACCIMLALLIVTKRFKRMPQRITFCLVLSQLMCCIGVILWSKMEHVH-RWPLYLQFLLFNIGTYSTRLWTGLLAISLLFLQCRSLCFVLKLWPYMLVFAWGVPAVLSALLIAFDSNVMSGEKHNPSFQYGNAQAAISVFMLVMCFIVTVGCLVLHQRYKKRYEKYMTYSRELSNPESESSDLHSTISTTNLLSHTDQSSIRQSVRTASYSSSSDDEEMIPTAAGLPTSRSNGAASGGAGSGGGGCGSGNG-TCCSGGAPVSNSSTTSTVVVDIEDLLNRTRQRASGANNKDLNKIESAPATEEIRNQMCSSSFNCGPSTSRQSCQTIIERYEDQNRRGLEPLEHPSDADEHQTLKHTVLLITLLCSMFVGLAVSIWTLVMEGMSGIYLELSFLDAFLNFGQGLIVLAVFITDIGELLMPVVKLWRKLWYGANVVSLPHWSNVRPETKHICEQFRNHHLENCKKDIAKDRRWRIRVYRRVFYGTEFVSWLIEVGLSKDRMEAVHYARHLVDGRVLRHINNVYHFEDKLLLYNFCSRI---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : ... * . :*: .: ***::****::***:*** ::* :::****.**. ****:*:* .:* *::. * *.*: ::*:.*. *** * :::***. . :::.**:.**.*******:*:*** ***: .:*** .*:**:**:** :***:*::: *:.: . . .: :: .: :: **:::*.::*:. *:: . :* :.. : *.:**..:*** ***.:** . . .: :** .*:*::**: * *::::. : . : *.**.:.****.**.**.. : *:::***:*::: .**..**:***:*::** ::::. :.. :: .*****: . : *::::::::::::*: :* *.::* : * *:::*. : . . * * *: . *** :*.**:.:**:::: . . :: .**:* : .:*: . :. :.:* **. * : . * .: : : :.: * :.. .. : . : . . . :. * *. * :....: .. :* * *. : : : * :*.:: : * :..*. .:* *. . . :*:**.*: .. *:***:* :..* * :: *. : . :* * * * : *:** ::* . * ::*.:.:* : .* * ::* ** .***:.*: *** *. :*::* *::**.: : *.*: * *.* ", "identical_positions": 219, "similar_positions": 304, "identity": "22.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100923-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q05516-1", "uniprot_id": "ZBT16_HUMAN", "id": "Q05516-1", "name": "Zinc finger and BTB domain-containing protein 16", "aln": "MDLTKMGMIQLQNPSHPTGLLCKANQMRLAGTLCDVVIMVDSQEFHAHRTVLACTSKMFEILFHRNSQHYTLDFLSPKTFQQILEYAYTATLQAKAEDLDDLLYAAEILEIEYLEEQCLKMLETIQASDDNDTEATMADGGAEEEEDRKARYLKNIFIS-KHSSEESGYASVAGQSLPGP-MVDQSPSVSTSFGLSAMSPTKAAVDSLMTIGQSLLQGTLQPPAGPEEPTLAGGGRHPGVAEVKTEMMQVDEVPSQDSPGAAESSISGGMGDKVEERGKEGPGTPTRSSVITSARELHYGREESAEQVPPPAEAGQAPTGRPEHPAPPPEKHLG-IYSVLPNHKADAVLSMPSSVTSGLHVQPALAVSMDFSTYGGLLPQGFIQRELFSKLGELAVGMKSESRTIGEQCSVCGVELPDNEAVEQHRKLHSGMKTYGCELCGKRFLDSLRLRMHLLAHSAGAKAFVCDQCGAQFSKEDALETHRQTHTGTDMAVFCLLCGKRFQAQSALQQHMEVHAGVRSYICSECNRTFPSHTALKRHLRSHTGDHPYECEFCGSCFRDESTLKSHKRIHTGEKPYECNGCGKKFSLKHQLETHYRVHTGEKPFECKLCHQRSRDYSAMIKHLRTHNGASPYQCTICTEYCPSLSSMQKHMKGHKPEEIPPDWRIEKTYLYLCYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FGS1-1", "uniprot_id": "E7FGS1_DANRE", "id": "E7FGS1-1", "name": "", "aln": "MDLTKMGAIHLQNPSHPTTLLQKANQMRLSGTLCDVVIMVDSQEFHAHRTVLACASKMFEILFHRNSQHYTLDFLSPKTFQQILEYAYTATLQAKLEDLDDLLYAAEILEIEYLEEQCLKILETIQASEENDTDVNMNENGAEDVEDRRIKYLKSAFISKKHSIQDGGYGTAARHRLALVSMVDKRSSESAQLGLSTVSPTKAAVEGLMSMGQSVLQGNIG-----QSFSHNIGNSSPLIDKIKTEMMQVDEDYQHEG-GFPRNGEGG--GDSRQHR--DTPGTPTRGSVITSARELHS----TDSSVDSQGDNNQASLIS---MASLADRHFASLCSIPSNHKSESMLPVPVSMASSLHVPPSLAMSMDFSAYGGLFHQSLIQREFFSKLGDFAVNVKHEVHTQKERCEVCDMELPDNEAAEQHRKLHGGVKTFGCEFCGKQFLDSLRLRMHMLSHSAGPKALVCDQCGAQFSKEEALEAHRQTHTGSDMAVFCLLCGKRFQTQKALQQHMEIHAGMRSYICSECERTFPSHTALKRHLRSHTGDHPFECEFCGSCFRDESTLKGHKRIHTGEKPYECNGCGKKFSLKHQLETHYRVHTGEKPFECKLCHQRSRDYSAMIKHLRTHNGASPYQCTICQEYCPSLSSMQKHMKAHKPEDVPPDWRIEKTYLYLCYV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******* *:******** ** *******:************************:**************************************** ************************:*******::***:..* :.***: ***: :***. *** *** ::.**.:.* : *. ***: .* *:.:***::*******:.**::***:***.: :. : *. * : ::********* .::. * .... .* **. :.* : ******.********** : ..* . .: .**. *. .::*:. : *: .***::::*.:* *::*.*** *:**:*****:****: *.:****:*****::**.:* * :* *:*.**.:*******.*******.*:**:***:***:**********:*:****.**:************:***:*******:**************:*.*******:***:********:*********************:****************.************************************************************************ **************.****::****************", "identical_positions": 483, "similar_positions": 123, "identity": "71.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-100930-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWS1-1", "uniprot_id": "D3ZWS1_RAT", "id": "D3ZWS1-1", "name": "Probable G-protein coupled receptor 174", "aln": "MTDNFTCNKTDGDNTDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVVFMINLAIADLLQILSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLMYPFRFNDCKQKYDLYISIVGWLIICLACLLFPLLRTNDDTPGNRTKCFVDLPIRNVNLAQSVAMITIGEVVGFITPLMIVLYCTWKTALSLQNKYPISQHLGEKKKALRMILTCAAVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPVIYYFTTNEFRRRLSRQELPDSIQLQTKSYKIVNNHGASPTAAELC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U507-1", "uniprot_id": "GP174_MOUSE", "id": "Q3U507-1", "name": "Probable G protein-coupled receptor 174", "aln": "MTDNFTCNKTDGDNTDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVVFMINLAIADLLQILSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLMYPFRFNDCKQKYDLYISIIGWLIICLACLLFPLLRTNDDTPGNRTKCFVDLPIRNVNLAQSVAMITIGEVVGFVTPLMIVLYCTWKTALSLQNKYPISQHLGEKKKALKMILTCAGVFLVCFVPYHFSFPLDFLVKSNEIKSCFARRVILIFHSVALCLASLNSCLDPVIYYFTTNEFRRRLSRQDLPDNIQLHTKSYKIASNHATSTVAAELC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXC1-1", "uniprot_id": "GP174_HUMAN", "id": "Q9BXC1-1", "name": "Probable G protein-coupled receptor 174", "aln": "MPANYTCTRPDGDNTDFRYFIYAVTYTVILVPGLIGNILALWVFYGYMKETKRAVIFMINLAIADLLQVLSLPLRIFYYLNHDWPFGPGLCMFCFYLKYVNMYASIYFLVCISVRRFWFLMYPFRFHDCKQKYDLYISIAGWLIICLACVLFPLLRTSDDTSGNRTKCFVDLPTRNVNLAQSVVMMTIGELIGFVTPLLIVLYCTWKTVLSLQDKYPMAQDLGEKQKALKMILTCAGVFLICFAPYHFSFPLDFLVKSNEIKSCLARRVILIFHSVALCLASLNSCLDPVIYYFSTNEFRRRLSRQDLHDSIQLHAKS--FVSNHTASTMTPELC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PUA0-1", "uniprot_id": "A0A8M9PUA0_DANRE", "id": "A0A8M9PUA0-1", "name": "Probable G-protein coupled receptor 174", "aln": "MNVSDTCSNSTS-IQDYQHQIYAVFYTLILIPGLIGNVLALWIFYAYVKETKKAVIFMINLAIADLLQVLSLPLRVYYYLNNSWPFGKAACMICFYLKYVNMYASIYFLACISLRRCRLIFKPLSCDIMKGQ-DRRWCFVGWFVVCVGCLPFPLLRQSERNP---QCCFAELPMMQLKKELGVSLLAVAEMTGFLLPLAIVITCTWLTTASLREKTCLLHDTGEKHKALKMVLSCACVFMICFVPYHITFPLDFLTKSNFNMSATFKNAVLHVHPITLCLASLNCCLDPVMYYFTTDEFKRRLSRTELQESFQLHQRI--FCPTNPEVTFKPNR-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . **... . *::: **** **:**:******:****:**.*:****:**:************:******::****:.**** . **:****************.***:** ::: *: . * : * .: **:::*:.*: ***** .: .. **.:** ::: .* ::::.*: **: ** **: *** *. **::* : :. ***:***:*:*:** **::**.***::******.*** *. :..:* .*.::*******.*****:***:*:**:***** :* :.:**: : : .: . .: ", "identical_positions": 166, "similar_positions": 99, "identity": "49.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101001-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P53420-1", "uniprot_id": "CO4A4_HUMAN", "id": "P53420-1", "name": "Collagen alpha-4(IV) chain", "aln": "MWSLHIVLMRCSFRLTKSLATGPWSLILILFSVQYVYGSGKKYIGPCGGRDCSVCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPK-DIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGP-GCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFGPGYLGGFLLVLHSQTDQEPTCPLGMPRLWTGYSLLYLEGQEKAHNQDLGLAGSCLPVFSTLPFAYCNIHQVCHYAQRNDRSYWLASAAPLPMMPLSEEAIRPYVSRCAVCEAPAQAVAVHSQDQSIPPCPQTWRSLWIGYSFLMHTGAGDQGGGQALMSPGSCLEDFRAAPFLECQGRQGTCHFFANKYSFWLTTVKADLQFSSAPAPDTLKESQAQRQKISRCQVCVKYS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QZR9-1", "uniprot_id": "CO4A4_MOUSE", "id": "Q9QZR9-1", "name": "Collagen alpha-4(IV) chain", "aln": "--------MRCFFRWTKSFVTAPWSLIFILFTIQYEYGSGKKYGGPCGGRNCSVCQCFPEKGSRGHPGPLGPQGPIGPLGPLGPIGIPGEKGERGDSGSPGPPGEKGDKGPTGVPGFPGVDGVPGHPGPPGPRGKPGVDGYNGSRGDPGYPGERGAPGPGGPPGQPGENGEKGRSVYITGGVKGIQGDRGDPGPPGLPGSRGAQGSPGPMGHAGAPGLAGPIGHPGSPGLKGNPATGLKGQRGEPGEVGQRGPPGPTLLVQPPDLSIYKGEKGVKGMPGMIGPPGPPGRKGAPGVGIKGEKGIPGFPGPRGEPGSHGPPGFPGFKGIQGAAGEPGLFGFLGPKGDLGDRGYPGPPGILLTPAPPLKGVPGDPGPPGYYGEIGDVGLPGPPGPPGRPGETCPGMMGPPGPPGVPGPPGFPGEAGVPGRLDCAPGKPGKPGLPGLPGAPGPEGPPGSDVIYCRPGCPGPMGEKGKVGPPGRRGAKGAKGNKGLCTCPPGPMGPPGPPGPPGRQGSKGDLGLPGWHGEKGDPGQPGAEGPPGPPGRPGAMGPPGHKGEKGDMVISRVKGQKGERGLDGPPGFPGPHGQDGGDGRPGERGDPGPRGDHKDAAPGERGLPGLPGPPGRTGPEGPPGLGFPGPPGQRGLPGEPGRPGTRGFDGTKGQKGDSILCNVSYPGKPGLPGLDGPPGLKGFPGPPGAPGMRCPDGQKGQRGKPGMSGIPGPPGFRGDMGDPGIKGEKGTSPIGPPGPPGSPGKDGQKGIPGDPAFGDPGPPGERGLPGAPGMKGQKGHPGCPGAGGPPGIPGSPGLKGPKGREGSRGFPGIPGSPGHSCERGAPGIPGQPGLPGTPGDPGAPGWKGQPGDMGPSGPAGMKGLPGLPGLPGADGLRGPPGIPGPNGEDGLPGLPGLKGLPGLPGFPGFPGERGKPGPDGEPGRKGEVGEKGWPGLKGDLGERGAKGDRGLPGDAG-EAVTSRKGEPGDAGPPGDGGFSGERGDKGSSGMRGGRGDPGRDGLPGLHRGQPGIDGPPGPPGPPGPPGSPGLRGVIGFPGFPGDQGDPGSPGPPGFPGDDGARGPKGYKGDPASQCGPPGPKGEPGSPGYQGRTGVPGEKGFPGDEGPRGPPGRPGQPGSFGPPGCPGDPGMPGLKGHPGEVGDPGPRGDAGDFGRPGPAGVKGPLGSPGLNGLHGLKGEKGTKGASGLLEMGPPGPMGMPGQKGEKGDPGSPGISPPGLPGEKGFPGPPGRPGPPGPAGAPGRAAKGDIPDPGPPGDRGPPGPDGPRGVPGPPGSPGNVDLLKGDPGDCGLPGPPGSRGPPGPPGCQGPPGCDGKDGQKGPMGLPGLPGPPGLPGAPGEKGLPGPPGRKGPVGPPGCRGEPGPPADVDSCPRIPGLPGVPGPRGPEGAMGEPGRRGLPGP-GCKGEPGPDGRRGQDGIPGSPGPPGRKGDTGEAGCPGAPGPPGPTGDPGPKGFGPGSLSGFLLVLHSQTDQEPACPVGMPRLWTGYSLLYMEGQEKAHNQDLGLAGSCLPVFSTLPFAYCNIHQVCHYAQRNDRSYWLSSAAPLPMMPLSEEEIRSYISRCAVCEAPAQAVAVHSQDQSIPPCPRTWRSLWIGYSFLMHTGAGDQGGGQALMSPGSCLEDFRAAPFVECQGRQGTCHFFANEYSFWLTTVNPDLQFASGPSPDTLKEVQAQRRKISRCQVCMKHS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "X1WFR7-1", "uniprot_id": "X1WFR7_DANRE", "id": "X1WFR7-1", "name": "", "aln": "--------MTRPHRIASTNLFFCRRLLLALLMIQTTLGGDK--TEECGGRDCSVCQCFPPKGEQGNPGMLGRQGPQGPQGSPGPPGLRGDKGERGTIGFPGVSGPKGELGARGVEGHAGLDGVPGHPGPGGLPGLPGKDGCNGTKGECGLNGEVGRPGLPGPVGLPGFKGAKGEPFYRTIYLPGKPGADGPPGMVGPQGLQGIAGPKGPPGWVGSDGPKGKPGLKGPRGPPGDPGRSLAGPKGDEGDQGIQGDPGPFEYVEPNPEDYIKGEKGEQGPRGYIGIPGQEGPEGPSAE--KGEKGVIGLPGVRGPPGYPGQTGRQGPKAERGVNGLPGLYGTKGLMGIPGD---PGPKGKPVESQKYVIGLPGDPGPPGNPGAPGDRGLMGIPGPSGDPGLSLPGAMG---DTGLMGLSGLKGQKGGAGSIYGSLLSYGEPGKRGFPGPKGQKGNPGTPGYYCLPGERGDLGRKGERGIVGYKGVQGRKGPDGGCACDP-PGDLPGDPGPPGPPGEPGDPGQKGFRGPLGEIGLSGDNGVNGITGSRGLTGPRGVKGKKGEVMTLSIKGEKGDLGPSGQHGKQGYTGKSGVDGIDGDPGDPGPLGDDLFGPPGDRGCQGAIGVKGVRGQTGPPGGCIMGSIGRRGQQGDPGPQGLAGFPGPKGLQGETLPCGPGIPGPRGCKGMPGGIGDKGKLGNPGCIGQNGTRGPKGEIGEPGDCGITGQRGPDGYLGDPGEPGPCGISINGSPGIPGSRGPEGLKGSCGDRMFGAPGPLGPSGVQGCQGPKGVPGPPGPIGLQGMSGVPGYPGRKGERGKDGAPGPPGRPGKSPEQCDKGDEGLPGKKGEQGLIGHRGYPGEKGSLGELGCPG-IGAKGARGKPGTPGPQGCIGLQGPAGVNGDGGNPGYPGPKGLPGPCGQNGCPGNIGQTGCLGPPGPKGLKGLNGCSGFPGFNGTKGQKGCVGPPGFPGDLFYHPVKGEIGPPGPNGENGFCGERGDKGDPGPPGTPGYPGLNGPPGFERGCRGPPGARGVPGEPGVRGPHGPKGIVGFPGENGDNGDPGLSGMPGTPGYRGYDGPKGDSGESICTPGRTGERGPCGDNGVPGPCGERGDNGDIGPAGPDGNCGPPGPPGINGHIGPPGVVGPPGTCGRHGLEGPPGPPGPPGSNGNEGCTGLRGPPGPPGLHGLDGLKGVKGEIGSRGLGSTGERGDQGPEGDKGDQGDPGSRGPSQTGVRGPKGPQGLQGDPGPMGPPGIVGEECR--VPMPGLGGERGFPGLDGPPGPMGLMGDPGNAFTVCGECGDPGGPGSLGFKGEKGCHGSGGTPGCQGPQGPKGEKGLCGLMGIPGLPGPMGDCGPLGPSGAKGDKGDTGPKGDPGNVIKPTTCPPPQGPPGDPGPPGQIGEVGKNGDNGSGGPKGEKGERGIIGIFGQTGPPGEDGPLGNPGDQGERGPAGFKGPPGPDGDRGPPGRNETLSTGFLLVMHSQSRYVPTCPAGLTQLWNGYSLLYLEGQERAHTQDLGQAGSCLPVFSTMPFSCCNMD-TCDYASRNDKSYWLSTNAPIPNKPLKGQDIEEHISRCVVCEAPTPTIAIHSQDRLDPVCPPKWRSLWTGFSFMMYTGSGDEGGGQSLTSTGSCLQDFRSQPFVECQGPRGTCSYFASIYSFWMT-IDMEHNDSSPHGP-VITEERQQRDSTSRCSICMMNDPNQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .* :.: *:: *: :* *..* ****:****:*.* **.:* ** * *** ** *. ** *: *:** ** * ** .* **: *. ** *..*:**:****** * * ** .* **::*: * * * * ** * ** :* **...: : * * * ** * * * *. ** * * * * * * * *:*. .: * *: *: * :* *** *:* ***** :* * :* ** * :* .. *****: *:** ** ** * .* * *. * * ***:* * * *: *** * : . : * ***** ** * ** * * ** * ** : .* :* *. * .*: *: * .* : . *:** *:**. * :* **: ** * * * **: * * :* :* ** .* *:* * * . ** ** ** *. ** * *: * *: * .* :* * .* * ** * ** **::: :**.**: * .* * * *. * ** *: ***** **. ..** :* * * * * **** : *. *.** * ** * * * ** :*::: *. ** * *: * * ** * *. * . * **. * ** . *.* * * :**** * * * *.** *** * :* ** ** ** ** * *: * * ** * ** * * .*:** * ** :*::* * ** ** . ..*::* *:**: * * * * ** **. *::* .* * ** * ** **..* * * .* *:.* ** ** ** * * * **: *:.* * ** ** * :* .*: * * :* ** * ** * . ** * .** *:.** ******* .* * * ** * **:.** * * * ** ** *. * :*.:**** **:*:** .* ** .* * **** .*:. . * .* :* *. * * * *::* * ** * * ** ** * * ** * ** *: * * *** * *. * * .*::** *.***:**.**** ** *: ** . * * * * **::***** * * .* * ** * * .** **.* *. : :* ** *::* ** *** * * * **.. : *: ** * **. * * * * * ***:* :* ** *: * * *:**. *: * **.* ** * .* :*:** . ** * ** ** * * :* * .* ** * *** * * * * **. ** *. ** ** * .* ***** ** ** * . *****:***: *:** *:.:**.******:****:**.**** **********:**: **:. .*.**.***:****:: **:* **. : *. ::***.*****: ::*:****: * ** .***** *:**:*:**:**:****:* *.****:***: **:**** :*** :**. ****:* :. : : :* .* .:.* : ** . ***.:*: . ", "identical_positions": 753, "similar_positions": 272, "identity": "44.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101001-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M462-1", "uniprot_id": "A0ABK0M462_RAT", "id": "A0ABK0M462-1", "name": "", "aln": "----MHPGLWLFLVSLCLTKELAE----AGQ-KSYRQPCGG-----------------------------QDCSG-----ACACSPEKGARGHTGPIGTQGPAGPEGFAGPTGLSGLKGERGSPGRLGPYGPKGDKGPIGVPGFVGISGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGTDGYPGVLGPPGLP---GHKGAKGEP----ASFQGSII-GMKGDPGLPGLHGITGPSGSPGSPGDAGPIGPPG-----FQGPPGPPGLPGPD-----GNMGLGFQG------EKGIKGD------------------VGLPGPAGPPPSTGELEFMGFP-----KGEKGSKGEPGPPGFPGRSGLPG-VPELGSIGEKGERG---ILGLPGPRGPVGSEGIQGYPGKQGKKGTSGFPG----TNGFPGIKGEKGSIGVRGPDSFTDAEGTVIS-GFPGDPGVPGLPGLRGDEGIQGQ--RGPAGTAGLPS-LTGLPGALGPQGSPGLKGDRGNSGRTTFGEAGLPGRVGLPGLPGLPGPSGPPGRTFVSGPLLSI--------EPGLPGLQGEQGLKGHQGIKGVKGDSGFCACEGGAPNIGPHGESGLPGIQGPIGLRGIKGTRGDPGSRGASGPTGTPGLFGPRGQTGLKGKKGEPTVSRGSKMAGD------------KGDPGPQGIPGLAGAPGKDGIPGLPGFPGTQGDDGS----GFPGERGLPGLPGEKGHDGPTG----PRGIGLPGLPGPRGLPGDKGVDGLPGQQGLRGAKG-----------------VTLPCIIPGSYGPSGFPGAPGFPGSKGARGLPGIPGKPGTHGSKGEPGSPGLIHL--PGFPGFPGARGEKGLPGFPGLLGKHGYPGKAGSPGVPGSKGVAG-DIFGAENGASGEQGLQGLPGDKGFPGDSGLPGPKGLSGKSGMLGPKGERGNPGTSGPPGQPGPSGSTDPFGIKGTSGLPGAPGLPGISGHPGKKGQRGDIGHPGSTGKRGLPGIKGLPGPQGLAGFLGSPGLSGVTGLPGIPGQKGEKGSSGPVGFPGLPGLPGLPGADGLKGFSGSFGKVGQPGQAGTPGEKGDRGDPGPVGISSPRPPMLNLWFKGEKGSQGSAGSDGFPGPRGDKGEPGIPGLPGAPGAPGQSNTIKGLS----GSPGSPGSMGRRGLPGLKGSLGIAGFPGIPGKSGSQGLTGTPGPLGATGIPGLKGDQGPTLGISGSPGPKGQPGELGFKGVKGKDGLVGDRGYPGNKGDSGKVGSAGDPGFPGSPG-LKGISGMNGDPGFPGSSGHVGSIGRPGPSGLIGPKGFPGLPGLHGLNGLPGTKGTHGTPGAS-ITGVPGPAGLPGP--KGEKGMPGIVIGDPGKQGLRGQKGDQGSPGLQGPAGTPGASGISLPSVIAGQPGDPGQPGLDGERGRPGLPGPPGPPGPSSDQGDPGDSGFPGIPGLQGLKGNQGLPGFSGLSGDLGLKGMRGEPGLMGTPGKIGPPGDPGFPGMKGKAGPRGFSGPQGAPGHTPIA-EARHVPPGPLGLPGIDGIPGLTGDPGSQGSVGLQGSKGLPGIPGKDGPSGLPGPSGILGDPGLPGLQGPPGFEGAPGNQGPIGQPGMPGHS-VRVGYTLVKHSQSEHVPPCPIGMSQLWVGYSLLFVEGQEKAHNQDLGFAGSCLPRFSTMPFIYCNINEVCHYARRNDKSYWLSTTAPIP--MMPVGETQIPQYISRCSVCEAPSQAIAVHSQDITVPQCPLGWHSLWIGYSFLMHTAAGTEGGGQSLVSPGSCLEDFRANPFIECSGARGTCHYFANKYSFWLTTVEERGQFQEQPVSENLKTGQLHTRVSRCQVEVLQLFGRVYEFCWNRERRKEKSLTLGWMPPPPRQDTTQPLPF--------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B1AVK5-1", "uniprot_id": "B1AVK5_MOUSE", "id": "B1AVK5-1", "name": "", "aln": "----MHPGLWLFLVSLCLTKELAE----SGQKMSYGKPCGS-----------------------------RDCHG-----VCTCFPEKGARGHPGPIGTQGPAGPEGFTGPTGLSGLKGERGSPGPLGPYGSKGDKGPIGVPGFVGISGIPGHPGQPGPRGPPGPDGCNGTQGAVGFPGPDGYPGILGPPGLP---GHKGAKGEP----VPFQGSIT-GIRGDPGLPGLDGIPGPSGSSGSPGDAGPIGPPG-----LQGPPGLPGLPGPE-----GNMGLGFQG------EKGVKGD------------------VGLPGPAGPPPSTGELEFMGFP-----KGKKGSKGEPGPPGFPGMSGPPG-VPEFGSTGEKGEKG---ILGLPGPRGPMGSEGIQGHPGRQGKKGTSGFPG----INGFPGIKGEKGDIGVRGPDSFTDADGAVIS-GYPGDPGVLGLPGLRGDEGVQGQ--RGPSGTPGLPS-LTGLPGALGPQGFPGLKGDQGNSGRTTFGEAGLPGRVGLPGLPGLPGPSGPPGRTFETGHLSNI--------EPGFPGLQGEQGPKGHQGLKGVKGDSGFCACEGGAPNIGPHGEPGLPGIQGPIGLQGFKGTKGDPGSRGASGPAGTPGLFGPRGQTGLKGKKGEPTVSRGSKMSGD------------KGDPGPQGTPGLAGTPGKDGRPGLPGLPGIQGDGGS----GFPGERGLPGLPGEKGHDGPIG----PPGIGLPGPPGPRGLPGDKGVDGLPGQQGLRGAQG-----------------VTLPCIIPGSYGPSGFPGAPGFPGSKGARGLPGIPGKPGTHGSKGGPGSPGLMHL--PGLPGFPGVRGEKGLPGFPGLPGKDGYPGKAGSPGLPGFKGAAG-DIFGAENGASGEQGLQGLPGDKGFPGDSGLPGPKGLNGKPGMLGPKGERGNPGTSGPPGQPGPSGSTDPFGIKGTSGFPGAPGLPGISGHPGKKGQRGDIGQPGSTGKRGLPGIKGLPGPQGSPGFLGSPGLSGVTGLPGIEGQKGEKGSSGPVGFPGLPGLPGLPGADGLKGFSGSFGKVGQPGQTGTSGEKGDRGDPGPVGISSPRPPMLNLWFKGEKGSRGSAGSDGFPGPRGDKGEPGIPGLPGPPGATGQTNTIKGLN----GRPGSPGSMGRRGLPGLKGSLGIAGFPGMPGKSGSQGLTGTSGLLGATGIPGLKGDQGQTLGISGSPGPKGQPGELGFKGVKGKDGLVGDRGYPGNKGDGGKVGITGDPGFPGSPG-LQGISGMNGDPGLPGSSGHLGSIGRPGPSGLIGPKGFPGAPGLHGLNGLPGTKGTHGTPGAS-ITGVPGPAGLPGP--KGERGVPGIVIGDPGKQGSKGQKGDQGSPGLQGPAGTPGAPGISLPSVIAGQPGDPGRPGLDGERGRPGPPGPPGPPGPSSDQGDPGDSGFPGIPGLQGFKGNQGLPGFSGLSGELGLKGMRGEPGLMGTPGKIGQPGDPGFPGMKGKAGPRGFSGPQGAPGHTPIA-EAMQVPPGPLGLPGIDGIPGLIGDPGSQGSVGLQGSKGLPGIPGKDGPSGLPGPSGILGDPGLPGLQGPPGFEGAPGNQGPIGQPGMPGHG-VRVGYTLVKHSQSEQVPLCPTGMSRLWVGYSLLFVEGQEKAHNQDLGFAGSCLPRFSTMPFIYCNINEVCHYARRNDKSYWLSTTAPIP--MMPVGQTQIPQYISRCSVCEAPSQAIAVHSQDIIVPQCPLGWHSLWIGYSFLMHTAAGAEGGGQSLVSPGSCLEDFRATPFIECSGARGTCHYFANKYSFWLTTVEERGQFREEPVSETLKTGQLHTRVSRCQVCMKTP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14031-1", "uniprot_id": "CO4A6_HUMAN", "id": "Q14031-1", "name": "Collagen alpha-6(IV) chain", "aln": "---MLINKLWLLLVTLCLTEELAA----AGE-KSYGKPCGG-----------------------------QDCSG-----SCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLP---GQKGSKGDP----VLAPGSFK-GMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPG-----LQGPPGPPGPLGPD-----GNMGLGFQG------EKGVKGD------------------VGLPGPAGPPPSTGELEFMGFP-----KGKKGSKGEPGPKGFPGISGPPG-FPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPG----LNGFQGIEGQKGDIGLPGPDVFIDIDGAVIS-GNPGDPGVPGLPGLKGDEGIQGL--RGPSGVPGLPA-LSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPP---GPPGPPSPEFETETLHNK--------ESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGD------------RGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ----GFPGEKGLPGLPGEKGHPGPPG----LPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKG-----------------ITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHL--PELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATG-DIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVS----GKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPG-FPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPS-ITGVPGPAGLPGP--KGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTA-EAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPGQS-MRVGYTLVKHSQSEQVPPCPIGMSQLWVGYSLLFVEGQEKAHNQDLGFAGSCLPRFSTMPFIYCNINEVCHYARRNDKSYWLSTTAPIP--MMPVSQTQIPQYISRCSVCEAPSQAIAVHSQDITIPQCPLGWRSLWIGYSFLMHTAAGAEGGGQSLVSPGSCLEDFRATPFIECSGARGTCHYFANKYSFWLTTVEERQQFGELPVSETLKAGQLHTRVSRCQVCMKSL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z091-1", "uniprot_id": "A0A8M6Z091_DANRE", "id": "A0A8M6Z091-1", "name": "", "aln": "------MRLWSFVLPFVLYAVSAQ----GGS--TLQEPCAG-----------------------------RDCSG-----PCPCFPLKGGRGQPGELGPVGSGGPEGFYGGPGPVGPKAEQGHIGRKGPPGQNGDKGPMGVPGYPGNDGVPGHPGQEGPRGPPGLDGCNGTQGDTGYSGLDGYSGIPGSPGFP---GLKGQKGEPSYLNIPSQNILTQGPPGPQGYPGPIGPRGPDGFDGLPGLPGPPGPPGSPGQGYKGEPGEKGDVGPQGV--RGNPSVQFNAPAISTINKGEKGD------------------VGPPGDPGHPLVNGVVEFVGIP-----KADKGIQGDKGYAGNPGLPGRQGPVNPFRYPGEVGEKG---ILGLPGGRGPPGLNGPPGLPGRKGFTGSEGFPG----QPGLNGPKGDIGDPGPPGP--IVDSPVFEIK-GSKGDRGFPGYPGFPGDTGYGGL--PGQPGAPGPPAFFTGRPGAPGFPGSRGPKGQRGNPGRDSYGSEGLPGSQGLSGPPGLPGPPGTS-----SNFIVTP--------LPGFPGQPGPRGPFGSQGIKGFKGENGDCNCLGGG-TIGAQGPPGPPGFPGFIGLNGLKGEIGDNGYQGLPGPQGPQGRRGDRGFNGRKGEKGNAFFPQGKGQKGD------------LGQQGPPGPLGFSNSPGRDGSPGFPGQPGLPGEPGF----GLTGDKGFPGIPGSKGRPGASG----EPGIGYPGVAGFKGMQGEPGFNGLPGPPGPPGSKGDSCRQAGLIDASLEEGGTPLPCRLPGIQGDKGFPGRPGVPGPKGRVGSAGLNGRPGFDGSKGERGEPGSGGR--PGPQGFPGPRGDAGLPGTTNI-GLQGSPGRDGFPGSPGPKGEPG-AVLGATPGDLGRQGRPGEPGDKGQPGVPGFPGNPGVDGRNGFPGIKGERGVNGLPGPVGPIGPPGELPQGGIPGPRGPPGAKGFDGPPGFPGLKGMRGDPGPPGPGGIKGIQGIPGIPGSQGFRGPPGPTGFTERDGIPGRPGIKGEKGSLGLLGFQGLPGSPGIPGGPGIKGLPGFRGQDGLIGRDGPRGPRGDRGEPGPPGPSTPPIPVERL-VKGEPGEPGIVGGPGFTGQRGDKGFPGPPGRPGFPGPPGFADQAKGLP----GQPGIPGVPGSSGFPGPKGFPGVMGFPGFSGVKGDNGVPGVPGFPGAQGPPGAKGEKGDSYASSGPTGPKGNIGNSGFPGGPGRPGEPGDSGFPGVLGYQGQKGFPGDPGIPGFVG-SSGPPGPRGLPGYPGLRGRDGDPGRPGGPGLPGDKGFPGSPGLDGLNGLPGSRGPPGVPGVI-EGGRVGPPGVNGQ--KGERGTS--QPGVPGRPGEKGVRGDTGARGLRGYPGNPGPPGQPSLSNIPGPLGDPGLPGLDGREGPFGPPGLPGPPGPGTVQGDRGDPGFPGRPGIIGPRGEPGGFGAPGLQGNPGFKGQRGEPGFSGVPGRPGSPGEPGDYGRSGPRGLKGTSGPVGNPGFVFASNITARMPSGDPGQPGLDGFAGQPGIPGLPGSPGNPGPKGFRGQVGRLGPVGLAGSPGFTGDPGPSGIQGPTGLQGPRGKPGLPGIPAPPTRS-TGIGYTLVKHSQSTRVPMCPEGMTRLWEGYSLLYVEGQEKAHNQDLGLPGSCLPHFSTIPFLYCTANEICYYASRNDKSYWLSTTAAIP--MMPVANQEISPYISRCSVCEVPSQPIAVHSQDLTIPTCPQGWRSLWIGYSFLMHTGAGGEGGGQSLMSPGSCLEDFRATPFIECNGARGTCHYFANKYSFWLTTVDVNEQFVQGPTQETLKGDQFRSRLSRCQVCMKIL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08120-1", "uniprot_id": "CO4A1_DROME", "id": "P08120-1", "name": "Collagen alpha-1(IV) chain", "aln": "MLPFWKRLLYAAVIAGALVGADAQFWKTAGTAGSIQDSVKHYNRNEPKFPIDDSYDIVDSAGVARGDLPPKNCTAGYAGCVPKCIAEKGNRGLPGPLGPTGLKGEMGFPGMEGPSGDKGQKGDPG---PYGQRGDKGERGSPGLHGQAGVPGVQGPAGNPGAPGINGKDGCDGQDGIPGLEGLSGMPGPRGYAGQLGSKGEKGEP----AKENGDYAKGEKGEPGWRGTAGLAGPQGFPGEKGERGDSGPYG-----AKGPRGEHGLKGEKGASCYGPMKPGAPG------IKGEKGEPAS-----SFPVKPTHTVMGPRGDMGQKGEPGLVGRKGEPGPEGDTGLDGQKGEKGLPGGPGDRGRQGNFGPPGSTGQKGDRGEPGLNGLPGNPGQKGEPGRAGATGKPGLLGPPGPPGGGRGTPGPPGPKGPRGYVGAPGPQGLNGVDGLPGPQGYNGQKGGAGLPGRPGNEGPPGK--KGEKGTAGLNG-PKGSIGPIGHPGPPGPEGQKGDAGLPGYGIQGSKGDAGIPGYPGLKGSKGERGFKGNAGAPGDSK--LGRPGTPGAAGAPGQKGDAGRPGTPGQKGDMGIKGDVGGKCSSCRAGPKGDKGTSGLPGIPGKDGARGPPGERGYPGERGHDGINGQTGPPGEKGEDGRTGLPGATGEPGKPALCDLSLIEPLKGDKGYPGAPGAKGVQGFKGAEGLPGIPGPKGEFGFKGEKGLSGAPGNDGTPGRAGRDGYPG----IPGQSIKGEPGFHGRDGAKGDKGSFGRSGEKGEPGS----------------CALDEIKMPAKGNKGEPGQTGMPGPPGEDGSPGERGYTGLKGNTGPQGPPGVEGP--RGLNGPRGEKGNQGAVGVPGNPGKDGLRGIPGRNGQPGPRGEPG-ISRPGPMGPPGLNGLQGEKGDRGPTGPIGFPG---ADGSVGYPGDRGDAGLPGVSGRPGIVGEKGDVGPIGPAGVAGPPGVPGIDGVRGRDGAKGEPGSPGLVGMPGNKGDRGAPGNDGPKGFAGVTGAPGKRGPAGIPGVSGAKGDKGATGLTGNDGPVGGRGPPGAPGLMGIKGDQGLAGAPGQQGLDGMPGEKGNQGFPGLDGPPG------LPGDASEKGQKGEPGPSGLRGDTGPAGTPGWPGEKGLPGLAVHGRAGPPGEKGDQGRSGIDGRDGINGEKGEQGLQGVWGQPGEKGSVGAPGIPGAPGMDGLPGAAGAPG-AVGYPGDRGDKGEPGLSGLPGLKGETGPVGLQGFTGAPGPKGERGIRGQPGLPAT------VPDIRGDKGSQGERGYTGEKGEQGERGLTGPAGVAGAKGDRGLQGPPGASGLNGIPGAKGDIGPRGEIGYPGVTIKGEKGLPG-RPGRNGRQGLIGAPGLIGERGLPGLAGEPGLVGLPGPIGPAGSKGERGLAGSPGQPGQDGFPGAPGLKGDTGPQGFKGERGLNGFEGQKGDKGDRGLQGPSGLPGLVGQKGDTGYPGLNGNDGPVGAPGERGFTGPKGRDGRDGTPGLPGQKGEPGML--PPPGPKGEPGQPGRNGPKGEPGRPGERGLIGIQGERGEKGERGLIGETGNVGRPGPKGDRGEPGERGYEGAIGLIGQKGEPGAPAPAALD-YLTGILITRHSQSETVPACSAGHTELWTGYSLLYVDGNDYAHNQDLGSPGSCVPRFSTLPVLSCGQNNVCNYASRNDKTFWLTTNAAIP--MMPVENIEIRQYISRCVVCEAPANVIAVHSQTIEVPDCPNGWEGLWIGYSFLMHTAVGNGGGGQALQSPGSCLEDFRATPFIECNGAKGTCHFYETMTSFWMYNLESSQPFER-PQQQTIKAGERQSHVSRCQVCMKNSS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VMV5-1", "uniprot_id": "Q9VMV5_DROME", "id": "Q9VMV5-1", "name": "", "aln": "MLPRDLRHLSGLLGVVYLLGSLVS--------VTLADG--------------------------------KICNT----TLCDCKGIKGRMGAPGPIGVPGLEGPAGDIGPPGRAGPLGEKGDVGEYGEQGEKGHRGDIGPKGEMGYPGIMGKSGEPGTPGPRGIDGCDGRPGMQGPSGAPGQNGVRGPPGKP---GQQGPPGEAG-----EGGINSKGTKGNRGETGQPGGVGPPGFDGDRGSKGDTGYAG-----LTGEKGDPGLPGPKGD--TGAVSELPYSLIGPPGAKGEPGDSLSGVLKPDDTLKGYKGYVGLQGDEGPQGPTGEQGAVGRN------GLPGARGEIGGPGERGKPGKDGEPGRFGDKGMKGAPGWTGADGLDGSPGERGEDGFTGMPGVQGGAGPPGIYDP-SLTKSLPGPIGSQGDIGPPGEQGPPGLPGKPGRRGPIGLAGQSGDPGLNGSRGPPGRSERGEAGDYGFIG-PPGPQGPPGEAGLPGRYGLHGEPGQNVVGPKGEPGLNGQPGLEGYRGDRGEVGLPGDKGLPGEGYNIVGPPGSQGPPGFRGLPGDDGYNGLRGLPGEKGLRGDDCPVCNAGPRGPRGQEGDTGYPGSHGNRGAIGLTGPRGVQGLQGNPGRAGHKGLPGPAGIPGEPGKVGAAGPDGKAIEVG-SLRKGEIGDTGDSGHRGDTGDDGEKGRDGSDGSKGERGETGQRGDYGDAGYQGRDGEPGRDGRDGAPGRNATTPKVYLIGEPGYDGIKGERGDDGDTGFKGVKGEPN-----------------------PGQIYDNTGEPGEDGYTGPKGVKGAKGEQGAIGLRGEIGDRGPAGEVIPGPVGAKGYPGPTGDYGQQGAPGLPGRDGEPGLDGGIGYKGQRGVPGQEVIQGEIGPPGRSGIKGFPGDVGAPGQYGLAGRPGPKGVKGEQGPDGAVGQTGLPGNKGQRGD----FLVGPPGPKGQPGRNGRQAPHGAKGQKGEVGSLGQNGQNGAKGSIGFSGRRGLLGNAGLQGLPGSPGIPGLPGMIGEIGERGEIGYNGRQGDIGPRGPNGEFGPKGLSGDDGPDGYPGANGLPGRKGETGNPGFPGRPGAKGVAAYSGIKGDDGESGLTGPIGYPGAPGAKGQRGPVG-DSQPALDGVAGRKGEVG-----SPGPNGLPGRHGLKGQRGDRGLPGQQGRPGEPGAKGLGGYPGRNGINGLKGATGFPG----PQGPKGPQGESGVVGLDGRNGQIGDQGPRGLIGEQGEQGEQGDEGEVGIPGRLENLRDRSFYRGFTGDQGLQGERGEQGDMGPIGFIGPPGAKGERGDIGYAGQLGFDGAEGLKGFQGDQGPRGPPGITLPAEKGDEGVAG-LDGRAGRPGHFGQKGAPGPPGENGPNGAIGHRG-PQIQGPPGPQGDVGFPGAPGHNGRHGLIGPKGELGDMGRQGERGESGY----AIVGRQGDIGDIGFQGEPGWDGAKGEQGYPGLPGKNGRVGAPGPRGPTGDAGWGGIDGMDGLVGPKGQPGVTYSYSMARPGDRGEPGLDGFQGEEGDGGAPGLIGFQGQRGAVGYRGDQGEVGYTGADGPQGQRGDKGYMGLTGAPGLRGLPGPQGEPAPAPPAPKSRGFIFARHSQSVHVPQCPANTNLLWEGYSLSGNVAASRAVGQDLGQSGSCMMRFTTMPYMLCDITNVCHFAQNNDDSLWLSTAEPMPMTMTPIQGRDLMKYISRCVVCETTTRIIALHSQSMSIPDCPGGWEEMWTGYSYFMSTLDNVGGVGQNLVSPGSCLEEFRAQPVIECHG-HGRCNYYDALASFWLTVIEEQDQFVQ-PRQQTLKAD-FTSKISRCTVCRRRGNSFVARTAKSRADASSGFTDGSASSNPSGSLKTDGNYRANWQSGRSSSPGSQSSPGSSSGSWSSGSNAGAYPGSNAGAYSGSNAGAYPGSNAGAYPGSNAAWQSRTNAGSSWHSGPVAGSVSNPGSYSSWSTGSSPGSNPESNAGSTRSSWITRSRGPSNYLNGRYQQRVHPSNLQAYDEYARHGGNTRQYNRRPREDTTAP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * . : . : * * ** * .* :* * * * * * * .::* * * .*.:* * * * *: * * * *. * :* :* * * .* * *: *. * . * :* *:. . * * * * * ** * * * * * * * * * * . * . ** *: :* * * * * . * :*: * * * * * * * * ** * * * * * .* * *. * . . * * * * * . * * * * ** *. * * * * * . * *. * * * * :*:.* * * * * .* * * * .* * * * * * *: * . * * * * * * * * * * * * * * * * * *.. *. *: * * * . * .* * * * *: * * .* * * ** *: * * * .* * * * .* * * * . . .* ** * .*. * * * * * *. * * .* * * *: * * .. * .* * * * * :* .* . * * .* * *. * * *:.* * * * * * * .* * * * * * ** * . * * ** *. * * :* * * * * * * .* *:*. * *::* * * * * * * * *: * * * * * * *: *: * * . . *: .. * * * .* * .* * * . . * . * * * *: * :* *: * * .* * * * .* * * * * * * * :*: * *: * *. * * * * * *: * *: *:*. . .* * * * * * * *: * * * * * * * * * * * * * **:.* . * *: * * * * * * * * * . .* *: * .* *. * * * * * ** *: * . * :*: * * * * * ** * **: * * * ** * * * * * * * * * * ** :* * * * * * * :* * * * * * * *: * * * * * * * * *. . * :.:**** ** *. . . ** **** . . * .**** .***: :*:*:* : * .::* :* .**.: **:* .:* * *: :: ***** ***..:. **:*** : :* ** **. :* ***::* * . * ** * *******:*** *.*** * :* *::: ***: :: * . * .:.:* . :::*** * ", "identical_positions": 505, "similar_positions": 191, "identity": "24.59%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101001-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADD3-1", "uniprot_id": "D4ADD3_RAT", "id": "D4ADD3-1", "name": "HECT-type E3 ubiquitin transferase", "aln": "MAS----SAREHLLFVRRRNPQMRYTLSPENLQSLATQN---------SMPENMALQRANSDTDLVTSESRSSLTASMYEYTLG-QAQNLIIFWDIKEEVDPSDWIGLYHIDENSPANFWDSKNRGVTGTQKGQIVWRIEPGPYFMEPEIKICFKYYHG-ISGALRATTPCITVKNPAVMMGAEGMEGCASGSLHSRKLVSFTLSDLRAVGLKKGMFFNPDPYLKMSIQPGKKSSFPTCAHHGQERRSTIISNTTNPIWHREKYSFFALLTDVLEIEIKDKFAKSRPIIKRFLGKLTIPVQRLLERQAVGDQMLSYNLGRRLPADHVSGYLQFRVEVPSSAQEDASPEAVGTILGVHTVNGDLGSPSDDEDMPGSHHDSTICANGPVSEDSVADG--TPKHSFRTSSTLEIDTEDLISTSSRNSPPRGRQDSLNDYLDAIEHNGPSRPGTASSSERPMGAS-PKLRSSFPTDTRLNAMLHIDSDEEDHDFQQDLGYPSSLEEEGGLIMCSRTSRIDDGSLTSQTKPEDDNPVENEDASVHETASLEERPENLPEVEDGSLPSGTAPDENEASVEPQPSADQGSTELCSSQEVDQPTSGTDAGASDTSVGSRRAASETESLDQGSEPSQVSSETEPSDPARTESVSEASTRPEGESDLEGADSSCNESVTTQLSSVETRCSSLESARFPETPAFSSQEEEDGACAAEPTSSGPTEGSQESVCTPGSLPAVQVPSREEEGSGAEATALSEQGELGEVWQRRGSLEGAAAAA-TAAATDSQPQEDGDPGDTQGACEGATAQEEGATGG-SQTNGHQPLRSLPSVRQDVSRYQRVDEALPPNWEARIDSHGRIFYVDHVNRTTTWQRPTAPPAPQVLQRSNSIQQMEQLNRRYQSIRRTMTNERPEENTSAI--DGAGEEADFHQASADFRRENVLPHSTSRSRLTLLLQSPPVKFLISPEFFTVLHSNPSAYRMFTNNTCLKHMITKVRRDTHHFERYQHNRDLVGFLNMFANKQLELPRGWEMKHDHQGKAFFVDHNSRTTTFIDPRLPLQSSRPTSALVHRQHLTRQRS----------------HSAGEVGED--SRHAGPPVLP--RPASTFNTVSRPQ------------------------------------YQDMVPVAYNDKIVAFLRQPNILEILQERQPDLARNHSLREKIQFIRTEGTPGLVRLSSDADLVMLLSLFEEEIMSYVPPHALLHPSYCQSPRGSPVSSPQNSPGTQRANARAPAPYKRDFEAKLRNFYRKLETKGYGQGPGKLKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHD--ILDLTFTVNEEVFGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSVFDARELELVIAGTAEIDLNDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSSIPYEGFASLRGSNGPRRFCVEKWGKITALPRAHTCFNRLDLPPYPSFSMLYEKLLTAVEETSTFGLE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6I6G8-1", "uniprot_id": "HECW2_MOUSE", "id": "Q6I6G8-1", "name": "E3 ubiquitin-protein ligase HECW2", "aln": "MAS----SAREHLLFVRRRNPQMRYTLSPENLQSLAAQN---------SMPENMALQRANSDTDLVTSESRSSLTASMYEYTLG-QAQNLIIFWDIKEEVDPSDWIGLYHIDENSPANFWDSKNRGVTGTQKGQIVWRIEPGPYFMEPEIKICFKYYHG-ISGALRATTPCITVKNPAVMMGAEGMEGGASGSLHSRKLVSFTLSDLRAVGLKKGMFFNPDPYLKMSIQPGKKSSFPTCAHHGQERRSTIISNTTNPIWHREKYSFFALLTDVLEIEIKDKFAKSRPIIKRFLGKLTIPVQRLLERQAG-DQMLSYNLGRRLPADHVSGYLQFKVEVTSSAHEDASPEAVGTILGVHTVNGDLGSPSDEEDMPGSHHDSTICANGPVSEDSVADG--TPKHSFRTSSTLEIDTEDLISTSSRNSPPRGRQDSLNDYLDAIEHNGPARPGAASSSERSMGAS-PKLRSSFPTDTRLNAMLHIDSDEEDHEFQQDLGYPSSLEEEGGLIMCSRASRIDDGSLTSQTKPEDDNPVENEDASIHETASLEERLENLPEVADGSLPSSTAPDENEANLEPQPSADQGSTELCSSQEVDQPTSGADAGASDTSGGSRRAASETESLDQGSEPSQVSSETEPSDPARTESVSEASTRPEGESDPEGADSSCNESVTTQLSSVETRCSSLESARFPETPAFSSQEEEDGACAAEPTSSGPAEGSQESVCTPSSLPAVQVPSREEEGSAAEAAALSEQGELGEVWQRRGSLEGAAAAAPAAAATDSQPQEDGDAGDAQGACEGATAQEEGATGG-SQTNGHQPLRSLPSVRQDVSRYQRVDEALPPNWEARIDSHGRIFYVDHVNRTTTWQRPTAPPAPQVLQRSNSIQQMEQLNRRYQSIRRTMTNERPEENTSAI--DGAGEEADFHQASADFRRENVLPHSTSRSRLTLLLQSPPVKFLISPEFFTVLHSNPSAYRMFTNNTCLKHMITKVRRDTHHFERYQHNRDLVGFLNMFANKQLELPRGWEMKHDHQGKAFFVDHNSRTTTFIDPRLPLQSSRPTSALVHRQHLTRQRS----------------HSAGEVGED--SRHAGPPVLP--RPSSTFNTVSRPQ------------------------------------YQDMVPVAYNDKIVAFLRQPNILEILQERQPDLARNHSLREKIQFIRTEGTPGLVRLSSDADLVMLLSLFEEEIMSYVPPHALLHPSYCQSPRGSPVSSPQNSPGTQRANARAPAPYKRDFEAKLRNFYRKLETKGYGQGPGKLKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHD--ILDLTFTVNEEVFGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSVFDARELELVIAGTAEIDLNDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSSIPYEGFASLRGSNGPRRFCVEKWGKITALPRAHTCFNRLDLPPYPSFSMLYEKLLTAVEETSTFGLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2P5-1", "uniprot_id": "HECW2_HUMAN", "id": "Q9P2P5-1", "name": "E3 ubiquitin-protein ligase HECW2", "aln": "MAS----SAREHLLFVRRRNPQMRYTLSPENLQSLAAQS---------SMPENMTLQRANSDTDLVTSESRSSLTASMYEYTLG-QAQNLIIFWDIKEEVDPSDWIGLYHIDENSPANFWDSKNRGVTGTQKGQIVWRIEPGPYFMEPEIKICFKYYHG-ISGALRATTPCITVKNPAVMMGAEGMEGGASGNLHSRKLVSFTLSDLRAVGLKKGMFFNPDPYLKMSIQPGKKSSFPTCAHHGQERRSTIISNTTNPIWHREKYSFFALLTDVLEIEIKDKFAKSRPIIKRFLGKLTIPVQRLLERQAIGDQMLSYNLGRRLPADHVSGYLQFKVEVTSSVHEDASPEAVGTILGVNSVNGDLGSPSDDEDMPGSHHDSQVCSNGPVSEDSAADG--TPKHSFRTSSTLEIDTEELTSTSSRTSPPRGRQDSLNDYLDAIEHNGHSRPGTATCSERSMGAS-PKLRSSFPTDTRLNAMLHIDSDEEDHEFQQDLGYPSSLEEEGGLIMFSRASRADDGSLTSQTKLED-NPVENEEASTHEAASFEDKPENLPELAESSLPAGPAPEEGEGGPEPQPSADQGSAELCGSQEVDQPTSGADTGTSDASGGSRRAVSETESLDQGSEPSQVSSETEPSDPARTESVSEASTRPEGESDLECADSSCNESVTTQLSSVDTRCSSLESARFPETPAFSSQEEEDGACAAEPTSSGPAEGSQESVCTAGSLPVVQVPSGEDEGPGAESATVPDQEELGEVWQRRGSLEGAAAAA------ESPPQEEGSAGEAQGTCEGATAQEEGATGG-SQANGHQPLRSLPSVRQDVSRYQRVDEALPPNWEARIDSHGRIFYVDHVNRTTTWQRPTAPPAPQVLQRSNSIQQMEQLNRRYQSIRRTMTNERPEENTNAI--DGAGEEADFHQASADFRRENILPHSTSRSRITLLLQSPPVKFLISPEFFTVLHSNPSAYRMFTNNTCLKHMITKVRRDTHHFERYQHNRDLVGFLNMFANKQLELPRGWEMKHDHQGKAFFVDHNSRTTTFIDPRLPLQSSRPTSALVHRQHLTRQRS----------------HSAGEVGED--SRHAGPPVLP--RPSSTFNTVSRPQ------------------------------------YQDMVPVAYNDKIVAFLRQPNIFEILQERQPDLTRNHSLREKIQFIRTEGTPGLVRLSSDADLVMLLSLFEEEIMSYVPPHALLHPSYCQSPRGSPVSSPQNSPGTQRANARAPAPYKRDFEAKLRNFYRKLETKGYGQGPGKLKLIIRRDHLLEDAFNQIMGYSRKDLQRNKLYVTFVGEEGLDYSGPSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFYKALLRILCDLSDLEYLDEEFHQSLQWMKDNDIHD--ILDLTFTVNEEVFGQITERELKPGGANIPVTEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSVFDARELELVIAGTAEIDLSDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSSIPYEGFASLRGSNGPRRFCVEKWGKITALPRAHTCFNRLDLPPYPSFSMLYEKLLTAVEETSTFGLE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RSA0-1", "uniprot_id": "A0A8M1RSA0_DANRE", "id": "A0A8M1RSA0-1", "name": "HECT-type E3 ubiquitin transferase", "aln": "MATGTTTTAREHLLVVRRRSPHMRYTLSPENLRSLSAQGGSGGGGSRGGAPEPMGLQRANSDTDLVTSDSRSSLTASTYQFTLG-RGQNLVISWDIKEEVDATDWIGLYHIDETCPANVWDSKNRGVNGTQRGQIVWRLEPGPYFMEPETKICFKYYHG-VSGALRATTPCITVKNPGVTVGAEGQVDGQSVTEHCRKLVSFTLSDIRAQGLKKGMFFNPDPYLKMSIQPGKRNGFPTFSHHGQERRTSIISNTTNPVWHGEKYTFVALMTDVLEIEVKDKFAKSRPIIKRFLGQLIIPVQRLLERHTAGDQHVSYTLCRRLPTEHVSGQLHFRVEITFNGHEDA----MGSLLGASAMNGDPGSPSDDEDVLQPVSRMVRGPSPTGSEGSLHGDAFRPDECMMDPEEDRLLRDGAPDLAEGAPAHTHRQSSLNDYLDAIEAPKPP-------GDRPLGASSPKLRSSFPTDTRLNAMLHIDSDED---------------EEG---HASRDTALTNG----MPRPEGHASSERGKGEVHVKN----------------------RERLESEAASSATDTEATASVSSSGTTKSQNGGGAEGGQEGAAISGGLTQSISSFQQPALRIQDEEGAAPQASSRTEGSSEAPAVSEASAS---AIYTVNEVGGATATNQPERMNSSE---------MTNQEEED----------------------------------------------------EEIWQRRRSLQASGNES------QAEAMELGNEVRRTADEAQAALITDGETGACAQVNGHQPMRSLPSVRHDISRYQRVDEPLPPNWEARIDSHGRIFYVDHVNRTTTWQRPTAPPAPQVLQRSNSIQQMEQLNRRYQSIRRTITNERTEEQAAEMPPDDLTTSDLLHHSIPEYRRDGVVGPASSRSRLTLLLQSPSAKFLTSPDFFTVLHSNPSAYRMFTSNTCLKHMISKVRRDAHHFERYQHNRDLVAFLNMFANKQLDLPRGWEMKHDHTGKPFFVDHNCRATTFIDPRLPLQSARPSSLLAHRQHLSRQRS----------------HSAGEVGDD--PRHAGPAVLP--RPSNTF-TANRNQ------------------------------------CQDLVPVAYNEKIVAFLRQPNIFDILQERQPELIRNHSLREKVQFIRNEGASGLARLSSDADLVILLSLFEEEVMSYVPPHALLHPSYCQSPRGSPVSSPQNSPGTQRANARAPAPYKRDFEAKLRNFYRKLETKGYGQGPGKVKLIIRRDHLLEDAFNQIMCYSRKDLQRSKLYVSFVGEEGLDYSGPSREFFFLVSRELFNPYYGLFEYSANDTYTVQISPMSAFVDNHHEWFRFSGRILGLALIHQYLLDAFFTRPFYKGLLRIPCDLSDLEYLDEEFHQSLQWMKDNDIED--MLDLTFTVNEEVFGQITERELKPGGANIPVSEKNKKEYIERMVKWRIERGVVQQTESLVRGFYEVVDARLVSVFDARELELVIAGTAEIDLGDWRNNTEYRGGYHDNHIVIRWFWAAVERFNNEQRLRLLQFVTGTSSIPYEGFASLRGSNGPRRFCVEKWGKITSLPRAHTCFNRLDLPPYPSFSMLYEKMLTAVEETSTFGLE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W326-1", "uniprot_id": "Q9W326_DROME", "id": "Q9W326-1", "name": "HECT-type E3 ubiquitin transferase", "aln": "MEP----PAAPVPLQPLAASSACLADRSPVDPIAVRLQQ-----------EEQAEGDDEEEEEEEEDDDDDPKEEEAFYEARNGNESDELEQAFQSALTLTNDVHVSVSEVEEHEPP--LASRNQEVAEVEEQQQQLGACALPQPSEASLTGSKETREPRHHQTLLSTKSCETPANNATLSPTNSYNG---------SIGSDGGSSVGGGARRKSWTLSP--------QSGGSTPLSGAKKKTKTGAPTTTLSNANGDGFNLWVARECFETVPAEMVDTLSMAEVDEEVDEEEDEEAAAVESLLG--AAAALQASAHVQRRQQQQHHQHLRQPSPPQHRPLERSWPPRAVGRDLKLQGDVFQFDILDTDERLAEEMAQGSGSSNNSPLA--------TPPVRFKPLLKKKIGPDSYINTISTQKVPVHQSYEFPTFPSSSAVGSSS--------SSPNSLQFPYLRQHRPLTRALSNGKASSSEEQ--------------ASPRLLLSPKRPRSPPSGCSTRSASPLDISLSPEQHSPTRGRG---------------------------VGGALQDAVPPGTPTFHGQRPQQRLLKRVGGGAGAGATG-------------GATGSPLVCPPTPTHHARRHARLQAVTANSSLASG-GAIPSDPPAVSSQLDYIYLQDGGQE----------QGQEQSD-----------------------------------------------------EVVHISSTRLP------------SIPERSAAAAAAAAAAAAGAALMEPGTGTVSGSSGAGAAGEPP---------------LPPAWEARMDSHGRIFYIDHTTRTTSWQRPGAAPSGGPAGREQ--HHRQQLDRRYQSIRRTITNESRAAQLYNLP------------TSANSNANSTAPAAPP----PATAIHPAILMLCRPDFYSLLHTNEAALAIYNRNAALKHMVMRIRRDPPCFQRYQYNKDLVALVNTFAQMSRELPSCWETKLDQSGKQFFIDHQHRRTSFMDPRLPVECPR---VVRHRQQHSQQQSSVGYYYPDLVDGNCLSATSGHINASPASSVSGVPPLPPPRPSSSSSSSRSSHGHGHNCNTTSAISCALNADRSAYGAAGMASAGATAAGYEDVPIAYNEKVIAFLRQPNILEILRERQGQHTMSRQLREKINILRVEGVPALERLGHDLQLTILLSLFEQEIMGFVPIEE-------RSPQGSPVLN-------SRMPQRAPPPFRRDFEAKLRSFYRKLESKGYGQGPHKLKLHIRRSHLLEDAFRRIMSANKKDLQRGRLAVLWDTEEGLDYGGPSREFFFLLSRELFNPYYGLFEYSANDTYTVQVSPLSAFVDNCHDWFRFSGRVLGLALVHQYLLDAFFTRPFYKALLRLPVALSDLESLDNEFHQSLQWIRDNDIGTGVDLGLTFCVTEELLGSVVDRELKPGGKNIIINEKNKKEYLERMIKWRLERGVQEQTESLVRGFYEVIDSRLVSVFDARELELVIAGTAEIDTNDWRLNTEYRSGYHDNHQVIVWFWQVIERFSNEQRLRLLQFVTGTSSIPYEGFSALRGSTGPRRFCIEKWGKPNALPRAHTCFNRLDLPPYPTPELLYEKLLLAVEETNTFGIE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .* * .. ** : :: * * : :.: : .:. .. : *: * ..::* :: : :.: .::* *. *:*: * .:. * . * *.. . . : . :* :*..* * * .. ::. . .: * *.: . . :*. :.* *.* . :. :: : .: ..:* . : .: * *: . .:*: :.. .: .*: ** : * : ** :* . : ... :* * : . . :* : .. . * : .: : . . :. .: : .: . . . . . * **. * *. .*:*: . .* .* . . . .. : . : .:. . .. . * : : . * :* .. :* : .. :. * : : : .. * .**:.* *: : : : . . . . .: : ** : .* . . * *** ****:********:**..***:**** *.*: *.: :: :**:*********:*** : : : .: . :. :.. . *. :* *:*:::**:* :* ::. *:.****: ::***. *:***:*:***.::* **: . :** ** * *: ** **:**: * *:*:*****::..* : ***: ::*:* ::*.:. . . :* . ** **:.: : : : **:***:*::********::**:*** : .:.****::::* **...* **. * :*.:******:*:*.:** . :**:**** . .* ***.*::********.******:******* *:** ***.*******.:** .:*****.:* * : ******.*********:***********************:**:****** *:*******:*****:***************.***: ***** **:********::**** *.*** *.**::*.:.:******* ** :.*******:***:***:**** :************:*:********************** .*** *****.****** ** *** .:***.**********************::****.******:***** .:*****************: .:****:* *****.***:*", "identical_positions": 517, "similar_positions": 357, "identity": "31.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101001-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYM9-1", "uniprot_id": "TEFF2_MOUSE", "id": "Q9QYM9-1", "name": "Tomoregulin-2", "aln": "MVLWESPRQCSSWTLCEGFCWLLLLPVTLLIIARPVK-LAAFPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNSDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCAT---DTGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GGQ4-1", "uniprot_id": "A0A8I6GGQ4_RAT", "id": "A0A8I6GGQ4-1", "name": "Tomoregulin-2", "aln": "MVLWESPRQCSSWTLCEGFCWLLLLPVTLLIIARPVK-LAAFPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNSDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCAT---DAGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UIK5-1", "uniprot_id": "TEFF2_HUMAN", "id": "Q9UIK5-1", "name": "Tomoregulin-2", "aln": "MVLWESPRQCSSWTLCEGFCWLLLLPVMLLIVARPVK-LAAFPTSLSDCQTPTGWNCSGYDDRENDLFLCDTNTCKFDGECLRIGDTVTCVCQFKCNNDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSCAT---DAGSGSGDGVHEGSGETSQKETSTCDICQFGAECDEDAEDVWCVCNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQDNTTTTTKSEDGHYARTDYAENANKLEESAREHHIPCPEHYNGFCMHGKCEHSINMQEPSCRCDAGYTGQHCEKKDYSVLYVVPGPVRFQYVLIAAVIGTIQIAVICVVVLCITRKCPRSNRIHRQKQNTGHYSSDNTTRASTRLI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BD12-1", "uniprot_id": "A0A8M2BD12_DANRE", "id": "A0A8M2BD12-1", "name": "", "aln": "MALCAVLRQTRRPPRQENRTHVVLITTYCFFCISPLKQLCAFPSSLSDCQTPTGWNCSGFEEQDTDLFLCDTNTCKFDGECLRIGDTVTCICDFKCSGDYAPVCGSNGESYENHCLLRKDACKLQTEVLVVSDGACPVGTRDAGSGSGDDANEGSAEISQKETSTCDICQFGAECDEDSEDVWCVCNIDCSHISFNPVCASDGRSYDNPCQVKEVSCQKQERIEVKYLGHCK--------------------EEKDQVSEVPWGLYIPCPERYKDYCVHGECEYPSNLSPPTCSCHSGFIGPQCDRKDYNVMYVVPGSGKLRYVLIASIIGALQVAIICLVVLCITRRCPRGNRIARQKQNVPHFNSENTLRASTRLI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* ** . *. ::*:.. :: *:* *.***:***************:::::.*************************:*:***..**.**********:*.* **: *** *:*:****:*:*.. *:******..:***.* ********************:************: .***:*****:****.**:**.******:*** **:*: *: :::.* . :*****:*:.:*:**:**:. *:. *:* *.:*: * :*::***.*:*****. :::*****::**::*:*:**:*******:***.*** *****. *:.*:** *******", "identical_positions": 223, "similar_positions": 92, "identity": "58.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101001-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AQ81-1", "uniprot_id": "A0A8I6AQ81_RAT", "id": "A0A8I6AQ81-1", "name": "", "aln": "MLALSSARRSASEVGATPYPILLLLVPRAQCSSSQESPTLSRSTSKNPVHPSVMGMRSQAVEEGVPPSVPRWTSFCIVKPRKAEPHSFREKVFRKKAPVCAVCKVTIDGTGVSCRVCKVATHRKCEAKVTSSCQALPPAELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFSLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTRLNPKVHDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGSKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKAAMELQPSQHRYVGYFSGLLSGSIRMNSSPLFLHYVFVPVLPAFEPNTGFQPFLKIYQSMQLVYTSGVYHITGPGPRQICISLEPALLLKGDVMVTCYHKGGQGTDRTLVFRVQFHTCTIHGPRLNFPKDQLDEAWADERFPFQASVEFVFSSSPEKVKGNTPRNDPSVSVDYNMTEPAVRWDSYENFNQHHEDSVDGSLAHTRGPLDGSPYAQVQ-RVPRQTPPAPSPELPPPPMLSVSSDSGHSSTLTTEHTAESPGRPPPTAAERQELDRLLGGCGVASAGRGAGRETAILDDEEQPSVGGGLHLGMYPGHRPGLSRRCSCRQGLREPCGVPNGGYYRPEGTLERRRPPYGG-YEGHPQGYTEASVEKRRLCRSLSEGPYPYAP---ELGKPANGDFGYRPAGYREVVILEDPGVPALCSCPACEEKMALPTAALYGLRLEREAGEGWSSEVGKPLLHPVRPGHPLPLLVPACGHHHAPVPDYGCLKSPKVGE---------EGHEGCSYAVCPEGRYG---HPGYPALVTYGYGGAVP---------SYCPAYGRAPHSCGSPSEGRGYPSPGAHSPQAGSVSPGSPPYLQSRKLG--YEAPAEDGRDKYSLPGPLASAGPLASTESPEP-SWRDGSSGHSTLPRSPRDA----QCSASSELSGPSTPLHTSSPVQGKESTRRQDTTRSPSLAPTQRLSPGEALPSVVQGVTEKTPELLASSRPEPLDPSPFSQTSTPSSPNGWPQERSPGGHTNSASPRSPVPTTLPGLRHAPWQGPQGPSDS-PDG--SPLTPVPTQMPWLVGSPEPPQSSPTPAFPLATSYETNGPTQPPLPEKRHLP----GSGQQS--------SPPARGTNQHVTFASPLPD--------VTQPPEHPLQENQSSVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWK--GDPSEQLVRHFLIETGPKGVKIKGCPTEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETSEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPVPVPAIVHFKVSAQGITLTDNQRKVFFRRHYPVNSITFSSTDPQDRRWTNP-DGTTSKIFGFVAKKPGSPWENVCHLFAELDPDQPASAIVTFITKVLLGQRK-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CGB6-1", "uniprot_id": "TENS2_MOUSE", "id": "Q8CGB6-1", "name": "Tensin-2", "aln": "---MKSSG-----------PVERLLRALGRRDSS-------RATSR---------------------------------PRKAEPHSFREKVFRKKTPVCAVCKVTIDGTGVSCRVCKVATHRKCEAKVTSSCQALPPAELRRSTAPVRRIEHLGSTKSLNHSKQRSTLPRSFSLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGSKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYVSYFSGLLSGSIRMNSSPLFLHYVFVPVLPAFEPNTGFQPFLKIYQSMQLVYTSGVYRIAGPGPQQLCISLEPALLLKGDVMVTCYHKGGQGTDRTLVFRVQFHTCTIHGSRLTFPKDQLDEAWADERFPFQASVEFVFSSSPEKVKGNTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGALAHTRGPLDGSPYAQVQ-RVPRQTPPAPSPELPPPPMLSVSSDSGHSSTLTTEHTAESPGRPPPTAAERQELDRLLGGCGVASAGRGAGRETAILDDEEQPSVGGGLHLGMYSGHRPGLSRRCSCRQGFREPCGVPNGSYYRPEGTLERRRPPYGG-YEGHPQGYAEASVEKRRLCRSLSEGPYPYAP---ELGKPANGDFGYRPAGYREVVILEDPGVPALCSCPACEEKLALPTAALYGLRLEREAAEGWSSEVGKPLLHPVRPGHPLPLLVPACGHHHAPMPDYGCLKPPKVGE---------EGHEGCSYAVCSEGRYG---HSGYPALVTYGYGGAVP---------SYCPAYGRAPHSCGSPSEGRGYPSPGAHSPRAGSVSPGSPPYLQPRKLG--YEISAEDGRDKYPLSGHLASTGPLASTESPEP-SWRDGSSGHSTLPRSPRDP----QCSASSELSGPSTPLHTSSPVQGKESNRRQDTTRSPSLAPTQRLSPGEALPSVVQGVAEKTPELLTSSRPEQLDPSPFSQTSAPGSPNGWPQERSPGGHTNSASPRSPVPTTLPGLRHAPWQGPRGTSDS-PDG--SPLTPVPTQMPWLVGSPEPPQSSPTPAFPLATSYDANGPIQPPLPEKRHLP----GSGQQP--------SPPARSTNQHVTFASPLPD--------VTQPPEHPLQENQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWK--GDPSEQLVRHFLIETGPKGVKIKGCPTEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVAKASSAALSCSPVPVPAIVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNP-DGATSKIFGFVAKKPGSPWENVCHLFAELDPDQPASAIVTFITKVLLGQRK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63HR2-1", "uniprot_id": "TENS2_HUMAN", "id": "Q63HR2-1", "name": "Tensin-2", "aln": "---MKSSG-----------PVERLLRALGRRDSS-------RAASR---------------------------------PRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSCRVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFSLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYAQVQ-RPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGG-YEGSPQGYAEASMEKRRLCRSLSEGLYPYPP---EMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGE---------EGHEGCSYTMCPEGRYG---HPGYPALVTYSYGGAVP---------SYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLS--YEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDA----PCSASSELSGPSTPLHTSSPVQGKESTRRQD-TRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDS-PDG--SPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLP----GPGQQPGPWGPEQASSPARGISHHVTFAPLLSDN-------VPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWK--GDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNP-DGTTSKIFGFVAKKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PKG9-1", "uniprot_id": "A0A8M9PKG9_DANRE", "id": "A0A8M9PKG9-1", "name": "", "aln": "MGCIFSKQ-----------QWEKETSSQPSDPPK------TRDHAEDAEILS------------------------LTELEKMGSHCFKERNFKKK-LHCAVCRQTLDSLGMYCRECKTAVHKKCEEKVSVPCEAVSDPPPLQNQMNVP----------------QSKASMETVMENLMGSHYDFDLTYITERIISVLYQSDLDEQSYSANLKVVAPMLKSKHQDKFLLINLSEKRHDICRLNPKVEEFGWPDLHAPPLDKICAVCKTMENWLNSDPNNVVVLHCKGNKGKTGVIVAAYMHYSKISAGADQALSTVAMRKFCEDKISSFILPSQNRYIYYFAGLLSGSIKMNSSPLFLHQIHVPVSPNYQSGGGYAPFLKIYQSLQLVYSSGKYDIQGPNSKTLCVNIEPALLLKGDILVKCYHRLSDVCKRECVFRVQFHTCSVHGSQLAFGKGELDHACTDDRFPSDATVELLFSTGPQRRGGDVPGNEPGVSADYGSTDPVVRWDSYENFNLHHEDSVED-ISHTRGPLDGSLYAQVKKRRAQGSSPSRCPTSIKPSTYSPTHSSSTSPIHLSVQPLSLSKDTSRSSAAPESLTPLPREKREKDENRERHRETAILDDGECSPLRPDRPVQSCYGH-PFSHTHSYCGPDLTSPHAIAVQPKHRTLPCNRTTPLSVRDLCVSQPDLLWERGRCLHHPCPESVRHLYSYPPQETHTHSPIPQTSHSHTLPPQTRAYFSGEACPLFHCSALPQGHNHIPPSLSPNQSLLTSPYRELRYSTTSPTSCSCRDCLRLREDVALHSLRGRELETLPWSREAEFGIRREAPVHWRDGRAESHWEGVQEAEYWRRKIAMSPVMLSYGHCQAVPKQEQAVYVTDPQPEHGLSPFPSPQSSGYHSPHPPCPCSPQPFRDSPGYASISHSQNSSPIALTPSPKRANHNRASAEENQHGPNEEYTKILSDDKSPATFSPPTQNSGPVKAGEMVQIKSPEDVNLPVSLITNISSASGAEDKTTITDCTSNSLLISSQPSSKNMESVQVQTLNPRPLSVPESEQDKGERPGSCYTSTTTSTS---PQPPLCSSERSSASEFSSFNLNGERQSVTPLTDCNEESNSDPDGFITPSFPIASHGYPLLTVPHVPYTGYT-----EITIPTN-LAQPPLPEKQRSSPLHNTSDYTPTSLIKSAGKPSVSSAQVHVSFSTTTNEVPPKSTCRIPLSSGVDEPESRLSSKFVQDSSKYWYKPGISRDQAIAVLKDKEAGCFLIRDSNSFQGAYGLALKVSTAPAHTNSHTEPGSAQEQLVRHFLIESGAKGVKIKGCQNETYFGSLSALVYQHSITPVSLPCVLRIPDRDLVGELQDLQSGTNTSTAADLLKQGAACNVLYLNSVETESLTGPQAVSKTTKCTLTQEPRPSPTVVHFKVSTQGITLTDNQRRLFFRRHYPIHSVTFSSVDPLDQRWVDA-DNTSCKMFGFVARRSG-ALGNVCHLFAELDPEQPATAIVNFINKVMLGPQQLRK--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHC3-1", "uniprot_id": "TENSN_DROME", "id": "Q9VHC3-1", "name": "Tensin", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRTPYEESAAAADHKYQYQYT--------------------------------AANNNNNYYKNYNVNGNGQANGNGNLSGIGN-------------------------GNGIGNGNGYGIPYHARENS---------------------LPFSYGIAKTSTPLRKTPTPTRVDSFLDFDFGPTNTNVNSNSSSNN--------------------GGTGDMIK-----PPTRLTSPLLVRKTLGNAVSPTSSTNTNTIANTYHYTSSSATPTPVRDNFEQLLRERREKVYN--EYRNLDRESSGERARVAPAPPQ-----------------RQYYPSDGYGIGLKNDSNGTLYRKSPSSNG-------------------------------------------------------------------------KSTKYNYDFEFNLNLDDVRPEPTPYTTRNIHFEDLRLDQDVPDGVVNRRTMERNYHTINSLETTHKRQ--------------------------------------------------------------------------------------------------------------------------------------QLEPLEQLGAVYGQNHMEETLTRT--------RRDLSASTSTSKSTSPLPAIG-------------------VPAIAPASPIYATSTKRVSNPNTNGQQQMTPSPTSRPE------------------------------------------------------TPAFPVTPRTPFGASSSSSASLAPTTQLPPESIYQTGPRRGVPP--------------------------------------------------------ALQPLEVSADSVQFARSSSQFWYKPNLTREDAIALLASAQPGTFLVRDSTTYKDSYGLVVRVSQPPP----------GSQELVRHFLIEPTKGGVHLKGCDDEPVFTSLSALVFEHSISQLALPCLLRLPDRD-----IVPPVRATTPAQQHLLAHGAATNVLWLYSCDTESLTGNEAIRKAIRQMYGQQPLPQPTEVHFKVSSQGITLTDNTRKKFFRKHYKADVISHCAIDPENRMWTSEGESDKKTIFAFVARRSHSSTDNQCHVFCDLSVSQPAAAIVSFANRTLPTEKLRNYVL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **. *:. : * :* . . : * *: :.* : * . . . : : :*: : : :: * : . :. :. *:. *:. *. :* .* *. :: .. .* . . :. : . . .. .:. :.: * . *: .. * . : . . . . . . * . . . * : : . .. . . . . . . ::. . : . *. . . . : . . : *.. . :* *:..: . . . * :. * . . . :*.:.:*::**** ::*::***:* . :.* **:*** :::.:***.::*: .*. ::********. **::*** *. * ****** :***: ::*** **:*.:* :. .: .** :*** .**:* * :****** :*: :: .* * *: ******:******** *: ***:** . ::..: ** :: *.. :. . .:*.***::. . * **:*.:*. .*** ***.* .:.: : ", "identical_positions": 140, "similar_positions": 202, "identity": "9.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101005-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UPW0-1", "uniprot_id": "FOXJ3_HUMAN", "id": "Q9UPW0-1", "name": "Forkhead box protein J3", "aln": "MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTGISKKNALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDVLPTRPKKRARSVERASTPYSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTSHPESVSQSLTPQQQ--PQYNLPERDKQLLFSEYNFEDLSASFRSLYKSVFEQSLSQQGLMNIPSESSQQSHTSCTYQHSPSSTVSTHPHSNQSSLSNSHGSGLNTTGSNSVAQVSLSHPQMHTQPSPH----PPHRPHGLPQHPQRSPHPAPHPQQHSQLQSPHPQHPSPHQHIQHHPNHQHQTLTHQAPPPPQQVSCNSGVSNDWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPTKPSQHIG----TGNLYIDSRQNLPPSVMPPPGYPHIPQALSTPGTTMAGHHRAMNQQHMMPSQAFQMRRSLPPDDIQDDFDWDSIV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BUR3-1", "uniprot_id": "FOXJ3_MOUSE", "id": "Q8BUR3-1", "name": "Forkhead box protein J3", "aln": "MGLYGQACPSVTSLRMTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTGISKKNALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDTLPTRPKKRARSVERASTPYSIDSDSLGMECIISGSASPTLAINTVTNKVTLYNADQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTNHPEPVSQPLTPQQQQQPQYNLPEREKQLLFTEYNFEDLSASFRSLYKSVFEQSLSQQGLMSIPSESSQQSHTSCSYQHSPSSTVTSHPHSNQSSLPNNH-SGLSATGSNSVAQVSLSHPQMHPQPSPH----TPHRPHGLPQHPQRPQHPAPHPQQHSQLQPPHSQHPPPHQHIQHHPNHQHQTLAHQPPPPPQQVSCNSGVSSDWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLKNWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVPQNVCHGAMHPAKPSQHIG----AGNLYIDSRQSLPPSVMPPPGYPHIPQALNTPGTTMAGHHGAMNQQHMMPSQAFPMRRPLPPDDIQDDFDWDSIV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2R8Q307-1", "uniprot_id": "A0A2R8Q307_DANRE", "id": "A0A2R8Q307-1", "name": "", "aln": "---------------MTSELESSLTSMDWLPQLTMRAAIQKADA-QNAHGPGMPKKSALLDPNTTLDQEEVQQHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSLNKCFLKVPRSKDDPGKGSYWAIDTNPKEDTLPTRPKKRPRSGERASTPYSLESDNLGMDCIISGSASPTLAINTVTNKVALYNPDQDGSDSPRSSLNNSLSDQSLASVNLNSVGSVHSYTPVTSHPESVSQSMSLQQAPQAQYSIPDRDKQLLFSEF--EDLSASFRSLYKTVFEQSYNQQSLMGLPSESSQQTHTSCSYQHSPS----SHPHNNQNSITNSHPNNIPNNGS----QVPLSHPPHSAHNSPHGQHLSQHGPHSQHPHTAHSQHPQ-HSQHPQHSQHSQHGHQAHGQHTAQQQQQQHQNLSHQ-----QQMQCNTGLLSDWYPNLDALKESCRIASNCNWSDVDLSPFQGLKESMRQAEMNNWSLEPTQMADLCSSINQFFAQTG-IQPQGAVQASVCHGSMHPNKASPHINRVCFSGNVYMDSRPSLS-SLMGPPGYTHMP-PMSSAGPTMTGHHPQMSQQHMMTGGNFQMRR-MPADDIQDDFDWDSIV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **************************:** *****.*:.**.********************************************************************************************************.********.** ********::**.***:********************:***.***************************************.***.***.:: ** .**.:*:*:*****:*: ************:***** .**.**.:*******:****:****** :***.**.*:.*.* ..: .** **.**** .: *** . * **. *. :. ** *.*: .: * .: * . ** :: ::***.*:** **:.**:*: .***..** *********. ******** **** ******:::****: .*:******:****:*** *:.*. * .****:*** *.* **. :**:*:*** .*. *:* ****.*:* .:.:.*.**:*** *.*****.. * *** :*.*************", "identical_positions": 432, "similar_positions": 106, "identity": "68.35%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101005-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IRU5-1", "uniprot_id": "CLCB_MOUSE", "id": "Q6IRU5-1", "name": "Clathrin light chain B", "aln": "MAEDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIEND-PGFGAPAASQVASAQPGLASGAGSEDMSTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQKKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADTIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09497-1", "uniprot_id": "CLCB_HUMAN", "id": "P09497-1", "name": "Clathrin light chain B", "aln": "MADDFGFFSSSESGAPEAAEEDPAAAFLAQQESEIAGIEND-EGFGAPAGSHAAPAQPGPTSGAGSEDMGTTVNGDVFQEANGPADGYAAIAQADRLTQEPESIRKWREEQRKRLQELDAASKVTEQEWREKAKKDLEEWNQRQSEQVEKNKINNRIADKAFYQQPDADIIGYVASEEAFVKESKEETPGTEWEKVAQLCDFNPKSSKQCKDVSRLRSVLMSLKQTPLSR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BFK7-1", "uniprot_id": "A0A8M2BFK7_DANRE", "id": "A0A8M2BFK7-1", "name": "Clathrin light chain", "aln": "MADDFG-FSAFDNGV--HTEEDPAAAFLAQQENEIAVIENDSTGFSLPEDGGAAPADTYTMSG-GDFGGSSAVNGDMFQDTNGMTDSYSAIAQVDIQRQEPESLRKWREEQKTRLEELDSASKAAEAVWREKAKKELEDWHIHQTEQMEKNKVNNR------------------ASEEAFLKECEDDSPGTEWEKVARLCDFNPKTSRQTKDVSRMRSVLISLKQTPLLR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*** **: :.*. :*************.*** **** **. * . .*.*:. ** *. . .::****:**::** :*.*:****.* *****:*******:.**:***:***.:* *******:**:*: :*:**:****:*** ******:**.::::*********:*******:*:* *****:****:******* *", "identical_positions": 135, "similar_positions": 50, "identity": "58.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101006-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PQK4-1", "uniprot_id": "UIMC1_RAT", "id": "Q5PQK4-1", "name": "BRCA1-A complex subunit RAP80", "aln": "MPRRKKKIKEASEGQNLEKKDLETTSSVSIKKKRRLEDLFIVISDSDGEETKEENGLQKMKTKQSNRSKCLAKRKIAQMSEEEQFALALKMSEQEAKEVNNQEEKEEELLRKAIAESLNSRWS-------SDASAARPRPLSTGPSSHP--------------HQDSTKDSG-----------TTEGIWQLAPPSLCKGSQISQGNEAEEGK--------EPWDHSENPEEEPLSGSSGSQDQSSRPVFENEKVKCFDRCTGHLAEHTQCGKPQESTGSGCAFPKAVQ------------------------------------------------GRGDTSRQCLP------------------------------------TPADTKGLQDIG--------------------------------------------------------------------------------------------------------GTVHYYWGVPFCPAGVDPDQYTSVILCQLEVYQKSLKMAQRQLVKKRGFGEPVLPRPP-----------FLIQNECGQEEQTSEKHEGLSEDVRAGAREERQGSGASVWHSETKDSQKSPITSLKQRLLLEEEPTTGRGQSSQGLFVEETSEEVLKSSEGDDAVPASQSIAVLTSKRDLVLMPEASTEEVTVCPETQLSSFEPLDLNGEDSVDGR--------EIPTELGMTVSNRQVDNRE-AGKDSRPPAVSASARVSCPLCNQDFPPTKIEQHAMYCTGLMEPETVLTRRRREAKKKSDGRTAAQPALDISRKEKCYLCKSLVPLGEYQCHVETCLQLANVDRENGTEGMRRPRVCAPVEGKPKQRLRKSKEKGHSQGRLLSLLEQSEHRTTGVERTPKCSEAGAFRMPSPD-VEEAGCSRERQSSLSKLNLNESPIKSFVPVSEATNCLVDFKGQFAFR----SQTKSGRGRRRKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5U5Q9-1", "uniprot_id": "UIMC1_MOUSE", "id": "Q5U5Q9-1", "name": "BRCA1-A complex subunit RAP80", "aln": "MPRRKKKIKEASESQNLEKKDLETSSCVSIKKKRRLEDLLIVISDSDGEETKEENGLQKTKTKQSNRSKCLAKRKVAHMSEEEQFALALKMSEQEAREVNNQEEKEEELLRKAIAESLNSCWS-------SAASATRSRPLAAELSSHS--------------HQENTKDSG-----------TTEGVWQLVPPSLCKGSHVSQGNEAEQRK--------EPWDHNENTEEEPVSGSSGSWDQSSQPVFENENVKCFDRCTGHLAEHTQCGKPQESTGSGYAFSKAVQ------------------------------------------------GRGDTSRQCLP------------------------------------IPADTKGLQDTG--------------------------------------------------------------------------------------------------------GTVHYYWGIPFCPAGVDPNQYTNVILCQLEVYQKSLKMAQRQLVKKRGFGEPVLPRPP-----------FLIQNECGQEDQTSDKNEGISEDMGDEAKEERQESRASVWHSETKDFQKSPIKSLKQKLLLEEEPTTSRGQSSQGLFVEETSEEGLKSSEGDNSVPTTQSIAALTSKRSLVLMPESSAEEITVCPETQLSFLEPLDLNREDSPDSR--------ELPIEVRMAVGDKQVANREDCMKENPPPAVSSSTRVSCPLCNQDFPPTKIEQHAMYCNGLMEQETVLTRRRREAKNKSDGRTAAQPALDANRKEKCYLCKSLVPLGEYQCHVEACLQLAKVDREDGIEGTRRPRVCAPVEGKQQQRLKKSKDKGHSQGRLLSLLEQSEHRTTGVEKKPKYSEVRTFRMPSPE-VEEASCSREMQSTLSQLNLNESPIKSFVPVSEATNCLVDFKEQFAFR----SRTKSGRGRRRKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96RL1-1", "uniprot_id": "UIMC1_HUMAN", "id": "Q96RL1-1", "name": "BRCA1-A complex subunit RAP80", "aln": "MPRRKKKVKEVSESRNLEKKDVETTSSVSVKRKRRLEDAFIVISDSDGEEPKEENGLQKTKTKQSNRAKCLAKRKIAQMTEEEQFALALKMSEQEAREVNSQEEEEEELLRKAIAESLNSCRP-------SDASATRSRPLATGPSSQS--------------HQEKTTDSG-----------LTEGIWQLVPPSLFKGSHISQGNEAEERE--------EPWDHTEKTEEEPVSGSSGSWDQSSQPVFENVNVKSFDRCTGHSAEHTQCGKPQESTGRGSAFLKAVQ------------------------------------------------GSGDTSRHCLP------------------------------------TLADAKGLQDTG--------------------------------------------------------------------------------------------------------GTVNYFWGIPFCPDGVDPNQYTKVILCQLEVYQKSLKMAQRQLLNKKGFGEPVLPRPP-----------SLIQNECGQGEQASEKNECISEDMGDEDKEERQESRASDWHSKTKDFQESSIKSLKEKLLLEEEPTTSHGQSSQG-IVEETSEE-------GNSVPASQSVAALTSKRSLVLMPESSAEEITVCPETQLSSSETFDLEREVSPGSR--------DILDGVRIIMADKEVGNKEDAEKEVAISTFSSSNQVSCPLCDQCFPPTKIERHAMYCNGLMEEDTVLTRRQKEAKTKSDSGTAAQTSLDIDKNEKCYLCKSLVPFREYQCHVDSCLQLAKADQGDGPEGSGR--ACSTVEGKWQQRLKNPKEKGHSEGRLLSFLEQSEHKTS--DADIKSSETGAFRVPSPG-MEEAGCSREMQSSFTRRDLNESPVKSFVSISEATDCLVDFKKQVTVQPGSRTRTKAGRGRRRKF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RMY1-1", "uniprot_id": "A0A8M1RMY1_DANRE", "id": "A0A8M1RMY1-1", "name": "BRCA1-A complex subunit RAP80", "aln": "MPRRKRTGDEGGRRAKVSRVELNEEP--------------LVISDSDHEEEENAN---KRSSRSVRWKRRENESHLRDMTEEEMLALAMRLSAQEANSAANREELEDSNIQKAIAESLNESVVKPSDGLENEAGSSSDQPLENEAETFTNMRRKLCYPSQDQTHNEIERETSPLPEMPDLSQTTSSHISSMSPAHISRPSADTQDKTSDKQTTISNTPEFEIFKSLSESQLSPVLTRQSSSSRRPVVCVEKLSQELISASADSLNIHTQNSIVTPSRANGSQFPEQVDSPFPKCPVFTQNNFRRGIDSIEDKSFNGKEDETQIPDEDTHLPTESSQGLSTDSDTCLSPSRKSQLSSPKFVPKIKEDATLTHRTPDQKPVEDQTTPREKESVTESASKTQSWEGFTSHMVLLLPDDDDEDEGSEEILSPSPILHKEKIIRPLKIEISPTQSHVSSSTINPSTQDTEMSRSVLEQDSKASRGAEFKPSYCKASRSSEENGERTVTYYWGVPFCPMGQNPDEYTSVIMCQMEVYEKSLKEAQRELLRKADWGKPVCPESPERSFGARRWKRHRATRLSEEEEENEVEAEKQSNTIIEEEEEEEARGESEVGTLNNADGGQSETYVVLSSPETKDEQVDKTPFLSQEEPETRAVDKHIRNSVSRDTSDETGTQCPAEQHVDETPNMEACEEDPTVCPETQMSESSTPELMMTSPAQAQSRADSEVMEVEDGGDAPAADEEIIMMMEQDADPAEPAAPHSEQMECPMCSRLFPISKIEMHAAYCDGEADQQSQVVRRTRNRRQLMEDTHQSEKSANL---EKCSVCHDLFPLQEYIQHVPLCIERSSTANQ--------------------------------ENGLLSALERTEQRST----VSASDEPGPSDVPTKSNCGFSDIVVMGTSESVSEAMVSSPSSTFTPPSENTQCLTESAR---------NSLRLSRKRKFKK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:. .* .. ::.: ::: . :****** ** :: * * .::. . : : :: .*:*** :***:::* ***... .:** *:. ::********. . *.:: :** .: . *:: ::. :. : .: *. : : * :*.: ::: * :. .:.: .*: ..* .: . .*: . : :. .:. *** . * . * * : *: * . * **. : :.: : . ** *:**:**** * :*::**.**:**:***:**** ***:*:.* .:*:** *..* . . : :: . : * *: : .**. . :. :. * :* : . ::* . ** .: :: :: : : . .: . . *:. *: *******:* .. :* . .: :: .:.:: : .: . * ::.**:*.: ** :*** ** ** * : :: :.** :: : :. :: : : *** :*:.*.*: ** ** *:: :.. . :. *** **::*:::: .* . :*: :. * : .** .:*.. ** *:**.: . : .* *: * ", "identical_positions": 161, "similar_positions": 234, "identity": "16.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101006-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08773-1", "uniprot_id": "RGS14_RAT", "id": "O08773-1", "name": "Regulator of G protein signaling 14", "aln": "-------------------------------------MPGKP-----------------------------KHLGVPNGR---------MVLAVSDGELTSTSGSQAQGEGRGSSLSIHSLPSGPSSPFSTDEQPVASWAQSFERLLQDPRGLAYFTEFLKKEFSAENVTFWQACERFQQIPASDTKQLAQEAHNIYHEFLSSQALSPVNIDRQAWLSEEVLAQPRPDMFRAQQLQIFNLMKFDSYARFVKSPLYQECLLAEAEGRPLREPGSSHLGSPDTARKKPKLKPGKSLPLGVEELGQLPLAE---GRPLRKSFRREMPGGAVNSALRRESQGSLNSSASLDLGFLAFVSSKSESHRKSLGSGEGESESRPGKYCCVYLPDGTASLALARPGLTIRDMLAGICEKRGLSLPDIKVYLVGKEQKALVLDQDCTVLADQEVRLENRITFQLELVGLERVVRISAKPTKRLQEALQPILAKHGLSLDQVVLHRPGEKQLVDLENLVSSVASQTLVLDTLPDAKTREASSIPPCRSQGCLPRTQTKDSHLPPLSSSLSVEDASGSTGKRQTCDIEGLVELLNRVQSSGAHDQRGLLRKEDLVLPEFLQLPSQRPGSQEAPP-------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97492-1", "uniprot_id": "RGS14_MOUSE", "id": "P97492-1", "name": "Regulator of G protein signaling 14", "aln": "-------------------------------------MPGKP-----------------------------KHLGVPNGR---------MVLAVSDGELTSTAGSQAQGEGRGSSLSIHSLPSGPSSPFSTEEQPVASWAQSFERLLQDPRGLAYFTEFLKKEFSAENVTFWKACERFQQIPASDTKQLAQEAHNIYHEFLSSQALSPVNIDRQAWLSEEVLAQPRPDMFRAQQLQIFNLMKFDSYARFVKSPLYQECLLAEAEGRPLREPGSSHLGSPDTARKKPKLKPGKSLPLGVEELGQLPLAEGPCGRPLRKSFRREMTGGAMNSALRRESQGSLNSSASLDLGFLAFVSSKSESHRKSLGSGESESESRPGKYCCVYLPDGTASLALARPGLTIRDMLAGICEKRGLSLPDIKVYLVGNEQKALVLDQDCTVLADQEVRLENRITFQLELVGLERVVRISAKPTKRLQEALQPILAKHGLSLDQVVLHRPGEKQPMDLENPVSSVASQTLVLDTPPDAKMSEARSISPCRSQGCLPRTQTKDSHLPPSSSSLLVEDASSSTGNRQTCDIEGLVELLNRVQSSGAHDQRGLLRKEDLVLPEFLQLPSQRPGSREAPP-------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43566-7", "uniprot_id": "RGS14_HUMAN", "id": "O43566-7", "name": "Regulator of G protein signaling 14", "aln": "-------------------------------------MPGKP-----------------------------KHLGVPNGR---------MVLAVSDGELSSTTGPQGQGEGRGSSLSIHSLPSGPSSPFPTEEQPVASWALSFERLLQDPLGLAYFTEFLKKEFSAENVTFWKACERFQQIPASDTQQLAQEARNIYQEFLSSQALSPVNIDRQAWLGEEVLAEPRPDMFRAQQLQIFNLMKFDSYARFVKSPLYRECLLAEAEGRPLREPGSSRLGSPDATRKKPKLKPGKSLPLGVEELGQLPPVEGPGGRPLRKSFRREL-GGTANAALRRESQGSLNSSASLDLGFLAFVSSKSESHRKSLGSTEGESESRPGKYCCVYLPDGTASLALARPGLTIRDMLAGICEKRGLSLPDIKVYLVGNEQ-ALVLDQDCTVLADQEVRLENRITFELELTALERVVRISAKPTKRLQEALQPILEKHGLSPLEVVLHRPGEKQPLDLGKLVSSVAAQRLVLDTLPGVKISKARDKSPCRSQGCPPRTQDKATHPPPASPSSLVKVPSSATGKRQTCDIEGLVELLNRVQSSGAHDQRGLLRKEDLVLPEFLQLPAQGPSSEETPPQTKSAAQPIGGSLNSTTDSAL----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58ID84-1", "uniprot_id": "A0AC58ID84_DANRE", "id": "A0AC58ID84-1", "name": "", "aln": "MEVQEWRRYSLWAASLTRMEQIQTQTVSFIMEISLSLQQQKPSVQSKEKRILSFNEITRGFSNLTRRNSLRRTIGRHNTMSDDHPHTLNKTLTVSDGELNVMSDEHAATQHSSSNSSLPTVPSEGSR----GVGQVASWAVSFERLLEDPVGVCYFTAFLKSEVSAENILFWSACEKFRKIPGHQTEQLKREALSIYNTFLSSNATSPINIDDRVRVEEKDVQNPHADIFQKAQQQIFKLMKFDSYTRFVRSQLYQSCMLANVEGRPLPLLDSR--GKPLALSKQTNSNSPREQAKFDRTKERLKAKPSAADAEDVVERRKVNLQGMMGKDKRKEKRGSWGESP---ISFKTGLVKSSEVEKLVSRSADG----KVDKYCCVFLPDGTASLTPARPGLTVRNMLTGLCEKRRLPLSDIIIYLQGKDKQPLSLDQDSSVLQDQQVTLELRVTFAVKVAFTGKTVAVVVKSNKTLQEALAAMLNKYRLRSHEATVTMRDSGQKISLNTPVTFLANKALILDKGVDEASSSKGNFSPPSFQ--DRRGAVDANMFSPGMSRPNVRQRN--PGLRRTYDMEGLVELLNRAQCCSADDQRGLLKKEHLMLPQFLQLPLDEVEEAETCRSLEDSCSSMGSFEGDCTPRVQSDTLEEGPSERDCSNLARETVV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : :* * .*:******. :. :. : .*. *: ::** * ***** ******:** *:.*** ***.*.****: **.***:*::**. :*:** :** .**: ****:* **:*** :. : *: : :*:.*:*: * ***:*******:***:* **:.*:**:.***** .* *.* : *:.: :. :. . . :* . . *: * . *:*.:** ..*. :.* : : ..** .: * :. : .*****:********: ******:*:**:*:**** *.*.** :** *::: .* ****.:** **:* ** *:** :::. :.* : .*..* ***** .:* *: * :..: .. * :.* . *: :* : *:**. . . . .* * * . . .* . *. . .* *:* *:*********.*...*.******:**.*:**:***** : . *: ", "identical_positions": 215, "similar_positions": 155, "identity": "32.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101006-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q06495-1", "uniprot_id": "NPT2A_HUMAN", "id": "Q06495-1", "name": "Sodium-dependent phosphate transport protein 2A", "aln": "MLSYGERLGSPAVSPLPVRGGHVMRGTAFAYVPSPQVLHRIPGTSAYAFPSLGPVALAEHTCPCGEVLERHEPLPAKLALEEEQKPESRLVPKLRQAGAMLLKVPLMLTFLYLFVCSLDMLSSAFQLAGGKVAGDIFKDNAILSNPVAGLVVGILVTVLVQSSSTSTSIIVSMVSSGLLEVSSAIPIIMGSNIGTSVTNTIVALMQAGDRTDFRRAFAGATVHDCFNWLSVLVLLPLEAATGYLHHITRLVVASFNIHGGRDAPDLLKIITEPFTKLIIQLDESVITSIATGDESLRNHSLIQIWCHPDSLQAPTSMSRAEANSSQ----------------TLGNATMEKCNHIFVDTGLPDLAVGLILLAGSLVLLCTCLILLVKMLNSLLKGQVAKVIQKVINTDFPAPFTWVTGYFAMVVGASMTFVVQSSSVFTSAITPLIGLGVISIERAYPLTLGSNIGTTTTAILAALASPREKLSSAFQIALCHFFFNISGILLWYPVPCTRLPIRMAKALGKRTAKYRWFAVLYLLVCFLLLPSLVFGISMAGWQVMVGVGTPFGALLAFVVLINVLQSRSPGHLPKWLQTWDFLPRWMHSLKPLDHLITRATLCCARP----------EPRSPPLPP-----RVFLEELPPATPSPRLALPAHHNATRL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60825-1", "uniprot_id": "NPT2A_MOUSE", "id": "Q60825-1", "name": "Sodium-dependent phosphate transport protein 2A", "aln": "MMSYSERLGGPAVSPLPVRGRHMVHGATFAYVPSPQVLHRIPGTSTYAISSLSPVTLTEHSCPCGEVLECHDPLPTKLAQEEEQKPEPRLSQKLAQVGTKLLKVPLMLAFLYLFVCSLDVLSSAFQLAGGKVAGDIFKDNAILSNPVAGLVVGILVTVLVQSSSTSTSIIVSMVSSGLLEVSSAIPIIMGSNIGTSVTNTIVALMQAGDRTDFRRAFAGATVHDCFNWLSVLVLLPLEAATGYLHHVTGLVVASFNIRGGRDAPDLLKVITEPFTRLIIQLDKSVITSIAVGDESLRNHSLIRIWCHPDTTEASTSMSRVEAIGS------------------LANTTMEKCNHIFVDTGLPDLAVGLILLAGSLVVLCTCLILLVKMLNSLLKGQVMSSRRSSTQTDFPAPFTWVTGYFAMVVGASMTFVVQSSSVFTSAITPLIGLGVISIERAYPLTLGSNIGTTTTAILAALASPREKLSSSFQIALCHFFFNISGILLWYPLPCTRLPIRMAKALGKRTAKYRWFAVLYLLVCFLLLPSLVFGISMAGWQAMVGVGTPFGALLAFVVLVNVLQSRSPGHLPKWLQTWDFLPRWMHSLQPLDGLITRATLCYARP----------EPRSPQLPP-----RVFLEELPPATPSPRLALPAHHNATRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F8W579-1", "uniprot_id": "F8W579_DANRE", "id": "F8W579-1", "name": "Sodium-dependent phosphate transport protein 2A", "aln": "MCSRPIRITTAEQTISIAVGCHDAG-------KCSSSLDLVS-NCGDADADASSIHWETGKHPCTTTMSSDS-------------SESRSAGMFSSV----LRIPLLLLLLYGFVCSLDVLSSAFQLAGGKVAGDIFQDSVILSNPVAGLMVGILVTVLVQSSSTSTSIIVSLVSSGLLEVKSAVPIIMGSNIGTSVTNTIVALMQAGERNEFKRAFAGATIHDCFNWLSVLVLLPLEVFSGLLSFLARVTVSSFQMHSGEEAPELLKTLTEPFTTLIIQLDKSVITGIALGDESMRNHSLIKVWCKSSVLVSSVNVTHAAVRNCTGLHCGRDGDLTWITQNITTHINTEKCRHVFVDTGLSDLAVGLILLAGSLMLLCSCLLFIVKVLNSLLKGQVAKVIEGVINTDFPYPLGWLSGYLAMLMGAGMTFIIQSSSVFTSALTPLIGIGVISLNRAYPLTLGSNIGTTTTAILAALASPKEKLPAACQIALCHFYFNIFGILLWYPFPLTRLPIRMASALGERTAKYRWFAVLYLLLCFLLLPCLVFGLSLAGWQAMVGVGAPFVALTLFVLLVNLMQARSPAHLPKTLRSWDFLPQWMHSLKPLDKLISRSTALCCSPLRIKDPEPLVEPSDLQKPADQCFDNPALEEIPAEPRVFRLRGLERCNSTPL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * *: . : . * * ... *. :. .. * .. ..: . ** .:. .. .*.* : .. *::**:* :** ******:*****************:*..*********:*********************:********.**:***********************:*.:*:*******:****************. :* * .:: :.*:**:::.*.:**:*** :***** ******:****.** ****:******::**:.. :...:::. . .. : . ***.*:******.*************::**:**:::**:********* . . :**** *: *::**:**::**.***::*********:*****:****::*************************:***.:: *******:*** *******.* ********.***:**************:******.****:*:****.*****:** ** **:*:*::*:***.**** *::*****:*****:*** **:*:* . * ** . *. . ***:*. . ** : *:* *", "identical_positions": 378, "similar_positions": 143, "identity": "56.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101006-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q06496-1", "uniprot_id": "NPT2A_RAT", "id": "Q06496-1", "name": "Sodium-dependent phosphate transport protein 2A", "aln": "MMSYSERLGGPAVSPLPVRGRHMVHGAAFAYVPSPQVLHRIPGTTTYAISSLSPVALTEHSCPYGEVLECHDPLPAKLAQEEEQKPEPRLSQKLAQVGTKLLKVPLMLGFLYLFVCSLDVLSSAFQLAGGKVAGDIFKDNAILSNPVAGLVVGILVTVLVQSSSTSTSIIVSMVSSGLLEVSSAIPIIMGSNIGTSVTNTIVALMQAGDRTDFRRAFAGATVHDCFNWLSVLVLLPLEAATGYLHHVTGLVVASFNIRGGRDAPDLLKVITEPFTKLIIQLDKSVITSIAVGDESLRNHSLIRIWCQPETKEASTSMSRVEAIGS--LANTTM--EKCNHIFVDTGLPDLAVGLILLAGSLVVLCTCLILLVKMLNSLLKGQVANVIQKVINTDFPAPFTWVTGYFAMVVGASMTFVVQSSSVFTSAITPLIGLGVISIERAYPLTLGSNIGTTTTAILAALASPREKLSSSFQIALCHFFFNISGILLWYPLPCTRLPIRMAKALGKRTAKYRWFAVLYLLVCFLLLPSLVFGISMAGWQAMVGVGTPFGALLAFVVLVNVLQSRSPGHLPKWLQTWDFLPRWMHSLQPLDGLITRATLCYARPEPRSPQLPPRVFLEELPPATPSPRLALP------------------AHHNATRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60825-1", "uniprot_id": "NPT2A_MOUSE", "id": "Q60825-1", "name": "Sodium-dependent phosphate transport protein 2A", "aln": "MMSYSERLGGPAVSPLPVRGRHMVHGATFAYVPSPQVLHRIPGTSTYAISSLSPVTLTEHSCPCGEVLECHDPLPTKLAQEEEQKPEPRLSQKLAQVGTKLLKVPLMLAFLYLFVCSLDVLSSAFQLAGGKVAGDIFKDNAILSNPVAGLVVGILVTVLVQSSSTSTSIIVSMVSSGLLEVSSAIPIIMGSNIGTSVTNTIVALMQAGDRTDFRRAFAGATVHDCFNWLSVLVLLPLEAATGYLHHVTGLVVASFNIRGGRDAPDLLKVITEPFTRLIIQLDKSVITSIAVGDESLRNHSLIRIWCHPDTTEASTSMSRVEAIGS--LANTTM--EKCNHIFVDTGLPDLAVGLILLAGSLVVLCTCLILLVKMLNSLLKGQVMSSRRSSTQTDFPAPFTWVTGYFAMVVGASMTFVVQSSSVFTSAITPLIGLGVISIERAYPLTLGSNIGTTTTAILAALASPREKLSSSFQIALCHFFFNISGILLWYPLPCTRLPIRMAKALGKRTAKYRWFAVLYLLVCFLLLPSLVFGISMAGWQAMVGVGTPFGALLAFVVLVNVLQSRSPGHLPKWLQTWDFLPRWMHSLQPLDGLITRATLCYARPEPRSPQLPPRVFLEELPPATPSPRLALP------------------AHHNATRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q06495-1", "uniprot_id": "NPT2A_HUMAN", "id": "Q06495-1", "name": "Sodium-dependent phosphate transport protein 2A", "aln": "MLSYGERLGSPAVSPLPVRGGHVMRGTAFAYVPSPQVLHRIPGTSAYAFPSLGPVALAEHTCPCGEVLERHEPLPAKLALEEEQKPESRLVPKLRQAGAMLLKVPLMLTFLYLFVCSLDMLSSAFQLAGGKVAGDIFKDNAILSNPVAGLVVGILVTVLVQSSSTSTSIIVSMVSSGLLEVSSAIPIIMGSNIGTSVTNTIVALMQAGDRTDFRRAFAGATVHDCFNWLSVLVLLPLEAATGYLHHITRLVVASFNIHGGRDAPDLLKIITEPFTKLIIQLDESVITSIATGDESLRNHSLIQIWCHPDSLQAPTSMSRAEANSSQTLGNATM--EKCNHIFVDTGLPDLAVGLILLAGSLVLLCTCLILLVKMLNSLLKGQVAKVIQKVINTDFPAPFTWVTGYFAMVVGASMTFVVQSSSVFTSAITPLIGLGVISIERAYPLTLGSNIGTTTTAILAALASPREKLSSAFQIALCHFFFNISGILLWYPVPCTRLPIRMAKALGKRTAKYRWFAVLYLLVCFLLLPSLVFGISMAGWQVMVGVGTPFGALLAFVVLINVLQSRSPGHLPKWLQTWDFLPRWMHSLKPLDHLITRATLCCARPEPRSPPLPPRVFLEELPPATPSPRLALP------------------AHHNATRL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PDN7-1", "uniprot_id": "A0A8M9PDN7_DANRE", "id": "A0A8M9PDN7-1", "name": "Sodium-dependent phosphate transport protein 2A", "aln": "-------------------------------MQAQTVHHYMRSEEKHVMEATG-----------------------------------------KHIFINICKIPLLLLFLYMFICSLDILSSAFQLAGGKVAGGIFKDNAVLSNPVAGLVVGILVTVLVQSSSTSTSIVVSLVSSGLLDVGSAIPIIMGSNIGTSVTNTIVALMQAGEREEFKRAFAGATVHDCFNWLSVLVLLPLEAITGMMRLMSEAIVESFNIVTGEKGPELLKVITEPFTKRIIQLDRTVIVGIATGQEVLRNKSLIKVWCQTQIAIQKNASFVPSENSTVLTTSLHMNAEKCTHLFVETRLSDLAVGLILLVCSLLVLCTCLLLLVKLLNSLLQGQVAKAIQKVINTDFPFPFSWLTGYLAILIGAGMTFVVQSSSVFTSAITPLIGIGVISIERAYPLTLGSNIGTTTTAILAGLASPGDKLAAAFQVALCHFIFNILGILLWYPVPHTRLPIRMACFLGERTAKYRWFAVLYLILCFLLLPSFVFALSMAGWQILMGICVPVVAVLLCIVILNRLQSHKPHLLPRWLQTWDHLPLWMHSLKPMDSIITRATLCCREAQTRDQSRTSPEDLTDYEEEKNHAPLAQNGSCLIYDHETETGAVFDSMNGKCSRL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * * : . :.: : . : : *:**:* ***:*:****:**************.******:***************************:**:******:*.**************************:* :*:************************* ** :: :: :* **** *...*:***:******: *****.:**..**.*:* ***:***::**:.: .: . .: . * ***.*:**:* *.*********. **::*****:****:*****:*** . :. :**** **:*:***:*:::**.********************:**************************.**** :**:::**:*****:*** *******:* ******** **:*************::*******:**.:****** ::*: .*. *:* :*::* ***:.* **:******.** *****:*:* :******* ..:.*. .. * : . . ** : :.:**", "identical_positions": 358, "similar_positions": 120, "identity": "54.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101006-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43250-1", "uniprot_id": "GRK6_HUMAN", "id": "P43250-1", "name": "G protein-coupled receptor kinase 6", "aln": "MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQPIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPEVPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLCSQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPPAPPKKGLLQRLFSRQDCCGNCSDSEEELPTRL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O70293-1", "uniprot_id": "GRK6_MOUSE", "id": "O70293-1", "name": "G protein-coupled receptor kinase 6", "aln": "MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQPIGRLLFREFCATRPELTRCTAFLDGVSEYEVTPDEKRKACGRRLMQNFLSHTGPDLIPEVPRQLVSNCAQRLEQGPCKDLFQELTRLTHEYLSTAPFADYLDSIYFNRFLQWKWLERQPVTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVRNERYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVAEEYTDRFSSQARSLCSQLLSKDPAERLGCRGGGAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDIEQFSTVKGVDLEPTDQDFYQKFATGSVSIPWQNEMVETECFQELNVFGLDGSVPPDLDWKGQPTAPPKKGLLQRLFSRQDCCGNCSDSEEELPTRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B5J2-1", "uniprot_id": "A0ACD6B5J2_DANRE", "id": "A0ACD6B5J2-1", "name": "G protein-coupled receptor kinase", "aln": "MELENIVANTVLLKAREGGGGNRKGKSKKWKQMLQFPHISLCEELRQTIEKDYNSLCERQPIGRLLFRQFCDTRPELRRCVRFLDAVAEYEVTPDEKRKECGQELLDKYLNTKSEDYIPEVTEEMVTKCAERLQQEACKELFMECTKLIHDYLSVAPFADYLDSMYYSRFLQWKWLERQPITKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGESMALNEKQILEKVNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGEAGFDEKRAVFYAAEICCGLEDLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNERYTFSPDWWALGCLLYEMIEGQSPFQQRKKKIKREEVERLVKEVEEEYSSKFSEDAKSLCKMLLAKDPSERLGCQGGGASEVKAHLIFRSINFKRLAAGMLEAPFIPDPQAIYCKDVLDIEQFSTVKGVELEPKDDSFYSKVSTGSVPIPWQNEMIETECFKELNILNLDGTVPPDLDWRGQPSPPPKQGLLQRLFGRQDCCGNCSDSEEE-PTRL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******************************:********* ***** ::*:**:**************:** ***** **. ***.*:*******:*** **:.* :::*. .. * ****..::*::*::**:* .**:** * *:* *:***.*********:*:.************:***********************************************:**************************************************:*** * ***********************************************************************:********************* ************************ ***:.:** :*:***. **.***:*****:**.* *** * :*:.:*****.*****.** ***********************:***.*:.**.*.:****.*******:*****:***::.***:*******:***..***:*******.************** ****", "identical_positions": 477, "similar_positions": 74, "identity": "82.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101006-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RYG7-1", "uniprot_id": "DOK3_RAT", "id": "B2RYG7-1", "name": "Docking protein 3", "aln": "--------------------------------------------------------MESVETPVKDGLLYQQHMK------FGKKCWRKVWALLYAGGPSGVARLESWDVRDGG--LGPGGDRPAGPGRRGERRIIRLADCVSVLPADGESCPRDTGAFLITTTERSHLLAAQHRQSWMDPICQLAFPSTGECSSGSGQAESPKRGFVPMEENSIYSSWQEVAEFPVVVQRTEATTRCQLKGPYLLVLGQDDIQLRETSKPQACYSWPYRFLRKFGSDKGVFSFEAGRRCDSGEGLFAFSSPRAPDICGAVAAAIARQ---------------RERLPELA--------MSPPCP-----------------------------------------------------------------------------------------------LPRALSLPSLEPP--------GELREVAPEYELAPSR-------KLPLTD------PGPQS-------------------------LPLLLSPTQDGTASSLYASVCKQTSK--------------HKATVEHLYENVFMLEASPGLSNGGPEAQEGPPGGRSPLGSPIYHNSEELSWPGSAHDSNLEAQYRRLLELELDDAGGAGRPGAQ--TGIKAKLVTLLTRERKKGP---------APCDRP-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZK7-1", "uniprot_id": "DOK3_MOUSE", "id": "Q9QZK7-1", "name": "Docking protein 3", "aln": "--------------------------------------------------------MESVEPPVKDGILYQQHVK------FGKKCWRKVWALLYAGGPSGVARLESWDVRDGG--LGPAGDRSTGPSRRGERRVIRLADCVSVLPADGESCPRDTGAFLITTTERSHLLAAQHRQSWVDPICQLAFPGTGECSSGSGQAESPKRGFVPMEENSIYSSWQEVTEFPVIVQRTEATSRCQLKGPYLLVLGQDDIQLRETSKPQACFSWPYRFLRKYGSDKGVFSFEAGRRCDSGEGLFAFSSPRAPDICGVVAAAIARQ---------------RERLPELA--------MSPPCP-----------------------------------------------------------------------------------------------LPRALSLPSLEPP--------GELREVAPGFELPTPR-------KLPLTD------PGPQS-------------------------LPLLLSPTQEGPASGLYASVCKQTSK--------------HTGTAEHLYENVCMLEASPGLTNGGPEAQEGPPGGRSPLGSPIYHNTEDLSWPGSAQDSNLEAQYRRLLELELDEAGSAGRSGAQ--AGIKAKLVTLLTRERKKGP---------APCDRP-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L591-1", "uniprot_id": "DOK3_HUMAN", "id": "Q7L591-1", "name": "Docking protein 3", "aln": "MTRGARLRSDARAQLNQLSLDGGTGSGQKGKCEEFPSSLSSVSPGLEAAALLLAVTMDPLETPIKDGILYQQHVK------FGKKCWRKVWALLYAGGPSGVARLESWEVRDGG--LGAAGDRSAGPGRRGERRVIRLADCVSVLPADGESCPRDTGAFLLTTTERSHLLAAQHRQAWMGPICQLAFPGTGEASSGSTDAQSPKRGLVPMEENSIYSSWQEVGEFPVVVQRTEAATRCQLKGPALLVLGPDAIQLREAKGTQALYSWPYHFLRKFGSDKGVFSFEAGRRCHSGEGLFAFSTPCAPDLCRAVAGAIARQ---------------RERLPELT--------RPQPCP-----------------------------------------------------------------------------------------------LPRATSLPSLDTP--------GELREMPPGPEPPTSR-------KMHLAE------PGPQS-------------------------LPLLLGPEPNDLASGLYASVCKRASG--------------PPG-NEHLYENLCVLEASPTLHGGEPEPHEGP-GSRSPTTSPIYHNGQDLSWPGPANDSTLEAQYRRLLELDQVEG--TGRPDPQ--AGFKAKLVTLLSRERRKGP---------APCDRP-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RE04-1", "uniprot_id": "A0A8M1RE04_DANRE", "id": "A0A8M1RE04-1", "name": "", "aln": "-----------------------------------------------------------MDVISKEGPLFLQGVK------FGKKIWRKSWLVLLEAGPAGVSRLELWDLRDGGGRMGFGISRPAG-FKRTDKRVIRLSDCLSITPAPAESCPTDCSAFFLNTTSCTFTIAAPQRDDWLTVLCRLAFQ---KSRSSEDSRRVQKDKYLPLADNELYSTWGTG-QFQVCVQSTESSQRLRLSGYYLLSADKETVSLLDLRTGEPIQRWPYRLLRRFGPVKGGIMIEAGRRCPSGEGQFIFQSKQGSQIHRAIEDAIMHQSVQELLAQASAIPQEPKNRPEVS--------KPPAIPQEPQN------------------------------------------------------------RPEISKPPEVTVNPQRPAIHCKRGQQIHKAIKEALALPSYTPQPPPSPKPKAQVKEVKREKPCPPVRPINKYHNTQKLTP------PPPPP-------------------------PPPLPKNRPPDWTNVLKNTDDPRRNISLPDPPAC---IRSSVSSPDDVLYSVIFPQAKPREVINLPAPPAMQTYEEKPSEGCFTEEEETPYTNLSSVERSIEDLYSTVNYAAKRKNRQAEESSEMP-ADFKQTLSSLLSKELGKTPPVFPGRSYGGSCDGLDRFDELMTD--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3R6-1", "uniprot_id": "Q9W3R6_DROME", "id": "Q9W3R6-1", "name": "", "aln": "---------------------------------------------------------MDVEIPVLAGYLNVPTQTGFSLNRISKKKACSRYCLLFKASRHGIARLEMCESKEDR-----------------NPKIFTLENCVKITQE-----PPPERLIHIVKRQATLTLSTSSEEELKDWITALQTVAFCDTSPSGGIGAIE-------EDNDLYCSSFDGLFIITLIPSEASIRCCIEPKTYMLQMTPTELQLKSEDLGATIAMWPYRFIRKYGYRDGKFTFEAGRKCTTGEGVFTLDHTNPQEVFRCMSAKMKSMKKLISGDSLSTLECGENQFSAAAGMEPGSRSPLPPSPSSNPHGGEFEINSTQSCISLRGFISSNDSLNNFSAGGGGASGATATGGGVLGSTGGITLSVPANSNSNSSSSKHIPNKPPRKSPTTHCDKYRNIVKYEPVAITTISSPSANSDVNSSVILKPLEGESISLPETAADLPPDLPLRNESASKAPPPERDYECIENITEAWRTRGVGDVRHSERMPILCDTSEFVRQRSVSKSTCGSQNTPKIIDIDIGEGCTSATSISESNYDRLDFLSPNNKTSSGYKTIVNVTPGNRIRCSPPPPNEYELIASPDTESFRKADDSHRGYGVLRKASTTTNNNNLGISNSNISGGSSTITTATANKGGNLEAAAIDHRSYNGLNYTMVSKPKRV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * * . :.** . : :* .. *::*** : ::. : ::: * :*:.: * : : . . : ::: .: : * . .. :*.:*.: : . : : :* :.* . . ***:::*::* .* : :****:* :*** * :. :: : : :. . : . * .. ::.: . . : : . . * * * * * : : . . : : . ... . . .: : . . : : . . :.:. :: : * . : ", "identical_positions": 39, "similar_positions": 115, "identity": "5.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101007-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ET62-1", "uniprot_id": "IMPG1_RAT", "id": "Q9ET62-1", "name": "Interphotoreceptor matrix proteoglycan 1", "aln": "MNLEIKHAILVLWIFLQVQGIKDTSTKTHSSGTKNIDKAPRIETTESTSAVHKASTMKRLFAVAKLRNKRSALFP-AVNICPRESLRQILESLQEYYRLRVCQEIVWEAYRIFLDRVPDTEEYQDWVSLCQKETFCLFDIGKNFSNSQEHLDLLQQRIFQRS--------FSGRKDDMSPIEILGVPTTAPVLPIDVSSMSLRPFPLPPDDTDLKEVTIKDIQTPIAIRRAELESKPEPTHVTEISSEE---------------KVEFSISLPNHRFKAELTNSRSPYYQELVGQSQLQLQKIFKKLPGFGEIRVLGFRPKKEEDGSSSTEIQLMAIFKRDHAESKGPESDLLSLDSNKIERERIHHGAIE-DKQPE-----AYLTAADLKKLIIRLLDGDQPLVGGTVPFSDEVTEPL--FRPVTQSELPKPLTDVTEDVTLSPELPFSEP-------------RLESVDIYGPYLP-----DSSWSRPVTASTSGVGNLPSFTP-SIFALDDQSSPPLMATGPTAFIPTLTLPISDYSTVRQWPLEVSHWPESSSDRELSTTSSHDTIRDLDEMDVSDTPALSEIAELSGYDS--------APDRFLEMTTPIP---------------------------------------------------TLQYVTXSSETIAAKGHELVVFFSLRVANMPFSYDLFNKSSLEYQALEQRFTDL------------------------------LVPYLRSNLTGFKQLEILSFRNGSVIVNSKVRFAKAVPYNLTQAVRGVLEDLRSTAAQELNLEIESYSLDIEPADQADPCKFLDCGKFAQCIKNELTEEAECRCRQGHESHG-----TLEYQELNLCPPG-KTCEASQGQATPCRPPD------------------------------------------------------------------------------------------------------------------------------HSTNQARQPSVKKLQR-QQNKVVKKRNSELSATDFEELDDQDWEGN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R1W8-1", "uniprot_id": "IMPG1_MOUSE", "id": "Q8R1W8-1", "name": "Interphotoreceptor matrix proteoglycan 1", "aln": "MNLQIKHAIFVLGIFLQVQGIKDTSIKIFSSEIKNIDKTPRIETIESTSTVHKVSTMKRIFDLPKLRTKRSALFP-AANICPQESLRQILASLQEYYRLRVCQEVVWEAYRIFLDRIPDTEEYQDWVSLCQKETFCLFDIGKNFSNSQEHLDLLQQRIKQRS--------FPGRKDETASMETLEAPTEAPVVPTDVSRMSLGPFPLPSDDTDLKEILSVTLKD---IQKPTTESKTEPIHVSEFSSEE---------------KVEFSISLPNHRFKAELTNSGSPYYQELVGQSQLQLQKIFKKLPGFGEIRVLGFRPKKEEDGSSSTEIQLMAIFKRDHAEAKSPDSHLLSLDSNKIESERIHHGVIE-DKQPE-----TYLTATDLKKLIIQLLDGDLSLVEGKIPFGDEVTGTL--FRPVTEPDLPKPLADVTEDATLSPELPFVEP-------------RLEAVDREGSELPGMSSKDSSWSPPVSASISRSENLPSFTP-SIFSLDAQSPPPLMTTGPTALIPKPTLPTIDYSTIRQLPLESSHWPASSSDRELIT-SSHDTIRDLDGMDVSDTPALSEISELSGYDS--------ASGQFLEMTTPIP---------------------------------------------------TVRFITTSSETIATKGQELVVFFSLRVANMPFSYDLFNKSSLEYQALEQRFTDL------------------------------LVPYLRSNLTGFKQLEILSFRNGSVIVNSKVRFAKAVPYNLTQAVRGVLEDLRSTAAQGLNLEIESYSLDIEPADQADPCKLLDCGKFAQCVKNEWTEEAECRCRQGHESHG-----TLDYQTLNLCPPG-KTCVAGREQATPCRPPD------------------------------------------------------------------------------------------------------------------------------HSTNQAQEPGVKKLR--QQNKVVKKRNSKLSAIGFEEFEDQDWEGN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q17R60-1", "uniprot_id": "IMPG1_HUMAN", "id": "Q17R60-1", "name": "Interphotoreceptor matrix proteoglycan 1", "aln": "MYLETRRAIFVFWIFLQVQGTKDISINIYHSETKDIDNPPRNETTESTEKMYKMSTMRRIFDLAKHRTKRSAFFPTGVKVCPQESMKQILDSLQAYYRLRVCQEAVWEAYRIFLDRIPDTGEYQDWVSICQQETFCLFDIGKNFSNSQEHLDLLQQRIKQRS--------FPDRKDEISAEKTLGEPGETIVISTDVANVSLGPFPLTPDDTLLNEILDNTLND---TKMPTTERETE----FAVLEEQ---------------RVELSVSLVNQKFKAELADSQSPYYQELAGKSQLQMQKIFKKLPGFKKIHVLGFRPKKEKDGSSSTEMQLTAIFKRHSAEAKSPASDLLSFDSNKIESEEVYHGTMEEDKQPE-----IYLTATDLKRLISKALEEEQSLDVGTIQFTDEIAGSLPAFGPDTQSELPTSFAVITEDATLSPELPPVEP-------------QLETVDGAEHGLP-----DTSWSPPAMASTSLSEAPPFFMASSIFSLTDQGTTDTMATDQTMLVPGLTIPTSDYSAISQLALGISHPPASSDD-SRSSAGGEDMVRHLDEMDLSDTPAPSEVPELSEYVS--------VPDHFLEDTTPVS---------------------------------------------------ALQYITTSSMTIAPKGRELVVFFSLRVANMAFSNDLFNKSSLEYRALEQQFTQL------------------------------LVPYLRSNLTGFKQLEILNFRNGSVIVNSKMKFAKSVPYNLTKAVHGVLEDFRSAAAQQLHLEIDSYSLNIEPADQADPCKFLACGEFAQCVKNERTEEAECRCKPGYDSQG-----SLDGLEPGLCGPGTKECEVLQGKGAPCRLPD------------------------------------------------------------------------------------------------------------------------------HSENQAYKTSVKKFQNQQNNKVISKRNSELLTVEYEEFNHQDWEGN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AJ68-1", "uniprot_id": "A0A8M3AJ68_DANRE", "id": "A0A8M3AJ68-1", "name": "Interphotoreceptor matrix proteoglycan 1", "aln": "MPLKTGLFLILFLFTLQATGIKEPTADDLVFKIRNVKYRHFLETPQQNRQLTDG---RDSLSLDRHRAKRSALFGTGVKVCPQESMAEVITSHKAYYKLRVCQEAVWEAFRIFLDRVPDTMEYQQWVYACQRDSLCIEDLARNFSSTQEHLDIVASRVNQLDEQDRALTPAPGEKCSKSPAELFIMESDSETGAPDVVPQRPVEHIVRFSVTVVDPVYSALLRDPASPQYEDLTRNLHDQMLHAFDKLPGFKEIQVLGFRAGGVEASYAVVFETDGTQAIGDTDSTDEYGIQGVLKGMVVKVLNEDTSLPVDVRSLTFEPDSSTADGQENLNSGTQISEKSRVLPGEMSTPSTKADSDDSIVPSGSLGIPFKDVDPDRTWDLGVGTERSFIQKVPDILSHATALPAGAELISSPSLEGSKAASLITEDTLATKGSQGSTTVDYLSKMPEDQEGAGNEIVSTAAPLDLRSFEAEKASTLAQSEMDFDSTPETTPAEATSSISTLITPTEQAKGAIFQVDDTIGPSESLETSNVGIPSYPTSPVDSPAIPTSIDPSDHLEPPSVSVTVDTLHLKVTPAGPTTPEPILPATILSQLTPTEDLISHPTPNNFLDEQEQVLRTASSPPHEGGADDEGETKQDVEQSDEEDETLDLGSGFPSEIDENPQSSARPLGYVTTPSIMASNQAKELVVFFSLRVTNMMFSEDLFNKSSPEYKSLENTFLELRQFSEPSDSTNPEASSQVPDREQKTLASIPLLPYLQSNLTGFKELEILNFKNGSVVVNSKMTLNKPVPYNVTETVQCVLEDFCNAASKRLNMEIDSQSVDVEAADHADPCKFMACNEFSRCVVNTLTEEGECLCDPGYSTVDGDPCTSICDLEPEYCLNG-GLCEIIPGHGATCRCPVGKFWHYHGERCSELVSVPVDPVLFVTCLVGSLSVVCAVIGILIFINKKCIRTRKSMRLVRPQSAFPFGNTMRVNPVFENDDGVLTHVSSILCPMSSDSASLQQSGQGTFRSIESLQLSIEIPRQLYTRRSEKLMSEMVDFHQYIPHNEMRRTSSRSSCCFLRSPDSEGFEVTVL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *: :::: : **. * *: : . :::. ** :.. : . : : : : * ****:* ..::**:**: ::: * : **:****** ****:******:*** ***:** **::::*: *:.:***.:*****:: .*: * . ...* . :. : : : . . ** . : . * :. : :. : : . . . ... :: : .. :* . : * . : :: : :. . .:: * *.*... ..... . * :: . . : . **:. * * :*: * .: : : *. .* * : . *: *.. : : . .::* : *.:.: * . : . .: : . : . . : .. : . :* *.: . .: * * . : : . .: . : . . . ** . ....**: : .: ::* .* : :.:**********:** ** ******* **::**: * :* *:***:*******:****.*:****:****: : *.****:*::*: ****: .:*:: *::**:* *:::*.**:*****:: *.:*::*: * ***.** * *:.: . :: * * * :.:.** * .: . : .:: :: : : .*. .. : :.:* . ", "identical_positions": 188, "similar_positions": 258, "identity": "17.52%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101007-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NB14-1", "uniprot_id": "UBP38_HUMAN", "id": "Q8NB14-1", "name": "Ubiquitin carboxyl-terminal hydrolase 38", "aln": "---------------------MDKILEGLVSSSHPLPLKRVIVRKVVESAEHWLDEAQCEAMFDLTTRLILEGQDPFQRQVGHQVLEAYARYHRPEFESFFNKTFVLGLLHQGYHSLDRKDVAILDYIHNGLKLIMSCPSVLDLFSLLQVEVLRMVCERPEPQLCARLSDLLTDFVQCIPKGKLSITFCQQLVRTIGHFQCVSTQERELREYVSQVTKVSNLLQNIWKAEPATLLPSLQEVFASISSTDASFEPSVALASLVQHIPLQMITVLIRSLTTDPNVKDASMTQALCRMIDWLSWPLAQHVDTWVIALLKGLAAVQKFTILIDVTLLKIELVFNRLWFPLVRPGALAVLSHMLLSFQHSPEAFHLIVPHVVNLVHSFKNDGLPSSTAFLVQLTELIHCMMYHYSGFPDLYEPILEAIKDFPKPSEEKIKLILNQSAWTSQSNSLASCLSRLSGKSETGKTGLINLGNTCYMNSVIQALFMATDFRRQVLSLNLNGCNSLMKKLQHLFAFLAHTQREAYAPRIFFEASRPPWFTPRSQQDCSEYLRFLLDRLHEEEKILKVQ--ASHKPSEILECSETSLQEVASKAAVLTETPR--TSDGEK-TLIEKMFGGKLRTHIRCLNCRSTSQKVEAFTDLSLAFCPSSSLENMSVQDPASSPSIQDGGLMQASVPGPSEEPVVYNPTTAAFICDSLVNEKTIGSPPNEFYCSENTSVPNESNKILVNKDVPQKPGGETTPSVTDLLNYFLAPEILTGDNQYYCENCASLQNAEKTMQITEEPEYLILTLLRFSYDQKYHVRRKILDNVSLPLVLELPVKRITSFSSLSESWSVDVDFTDLSENLAKKLKPSGTDEASCTK--------------LVPYLLSSVVVHSGISSESGHYYSYARNITSTDSSYQMYHQSEALALASSQSHLLGRDSPSAVFEQDLENKEMSKEWFLFNDSRVTFTSFQSVQKITSRFPKDTAYVLLYKKQHSTNGLSGNNPTS-GLWINGDPPLQKELMDAITKDNKLYLQEQELNARARALQAASASCSFRPNGFDDNDPPGSCGPTGGGGGGGFNTVGRLVF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JQ29-1", "uniprot_id": "A0AC58JQ29_DANRE", "id": "A0AC58JQ29-1", "name": "", "aln": "MSTVTGCSAYFAFPVVQYSPTMDKILEALVSSSHPQNVKRAIVKKVMEAAEKEVTEEQCQALYHLTTRLILQGEDVFQRQIGFQVQEAYARYHRDEFARFFSKEFVLSLLQQGYGSLDHRDPAILDFIHSSLRLLISCPAVLELAPLLQTEVLRIICERPEPATCAKLATILTDFSQCIPREKAGVLFCQQLVRTFAYFHCPASEERELREYVTQVSRVSALLQVIWKAEPTTLLPSLQEVFSIISSTDPSFEPSIALASLVQHIPLQMITVLIKSLTTDQNVKDASMTQALCRMIDWLSWPLANHVDTWVIALLKGLAAVQKFTILIDVTLLKIEQVFNRLWYPIVRQGALVVLSHMLLSFQHSPEAFHLVVPHIVPLVKSLKNDGLPNSKTFLLQFAELIHCMMYQYSGFPDLYDSILESIKELPKPSEEKIKFVLNQSAWTSQSNSFASGLLKITGKSETGKTGLVNLGNTCYMNSILQILFMATDFRRHVMSLQLNGSNTLMKKLQLLFAFLAHTQRAAYSPRSFLDVSRPTWFSAGSQQDCSEYLRFLLDRLHEEEKALSALQMASPKPEPATTSPETLHNAVSPPISDVPSHPDPAAAQGETGTLVERMFGGRLSTAIRCLQCHSLSEKEEPFTDLSLAFCPSMSQPRGPTNEHKSSSTL---GPCQGAVNGGSE------------ASEGPVKEGAASG--------------------------MERPMVEPTISVPDLVDYFLAPEILENENCYFCECCASLQRAEKAMRVVAAPEYLILTLLRFSYDATCHVRRKILDNVGIPLHMSLPLHQHSSSSSSNVAASSSSESPDSCENLAKKLKPSQKEEGIAESRMKSKKNNSDLQKLSVPYVLSSVVMHSGMSSDSGHYYSYGRNVSSDDG---CVAQTSPKSLDNSS----QSESSTAPQEETGRADPKSADWFLFNDSRVTFTNFQSLQNVTSRFPKDTAYVLIYRKQEVSGEASNSGPVVNGARLSGEPPLQKELMDAITKDNKLFLQEQELNARTRALQATSASCSFRPNGSDDNEPPGSCGPSGGGGGGGFNTISRLVF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******.******* :**.**:**:*:**: : * **:*::.*******:*:* ****:*.** ******** ** **.* ***.**:*** ***::* ****:**..*:*::***:**:* .***.****::****** **:*: :**** ****: * .: ********:.:*:* :::********:**::** *** ******:**********: *****.*****:******************:***** ***********************:******************************* ******:*:** ***.******************:***:* **:*:******.*.:**:*::********:********:.***:**::*********::************:** * :::**********:**********::* *********:*:**:***.*:****** ********** **:** *::.***.**:. ********************* *.. ** **. ..** : *:. : :.. * :::**. **:*:****:* * ****:*:* *:* *.*********** * . ..:: **.:: * *.:* * ** .:. *:* : .. ::* *.* **.**::******** .:* *:** *****.***:*::. ************** . **********.:** :.**::: :* ** . : * . : .* .********** .:*. . . ***:*****:***:**:*******.**::* *. *:.. :* .*. :*.:* *: . . * :************.***:*::************:*:**. :. *...*. * :.*:*****************:*********:*****:********** ***:*******:**********:.****", "identical_positions": 664, "similar_positions": 213, "identity": "61.31%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101007-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUJ7-1", "uniprot_id": "D3ZUJ7_RAT", "id": "D3ZUJ7-1", "name": "", "aln": "MAGLGPTFPLHRLVWANRHRELEAALHSRKHDIEQEDPRGRTPLELAVTLGNLESVRVLLRHNANVGKESHQGWAVLQEAVSTGDPEMVQLVLQYRDFQRATQRLAGIPELLNKLRQAPDFYVEMKWEFTSWVPLVSKMCPSDVYRVWKRGESLRVDTSLLGFEHMAWQRGRRSFIFRGQEAGALVMEVDHDRQVVHTETLGPALHEPEVLLAAMRPSEEHVASRLTSPIVSTHLDTRNVAFERNKCGIWGWRSEKMETVSGYEAKVYSATNVELVTRTRTEHLSDQDKLRNKGGKTPFQSFLGMAQQHSSHTAAPVQQAASPTNPTAISAEEYFDPSFSLESRNIGRPIEMSSKVQRFKATLWLSEEHPLSLGDQVTPIIDLMAISNAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARITFSNLCGCDEPVSSVCVPKPSSAISASGSP--FPCEVDPTVFEVPEGYSVLGAERSEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTVWEALTNTRPGIHPPPRVTVFEEQLQLEQ--ALQESLQLSTESRG---------PESPQKTPP-------PPAPP-------SFEEQLRLALELSSREQEELERRGQQEEEDLQRILQLSLTEH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PD24-1", "uniprot_id": "AN13D_MOUSE", "id": "Q6PD24-1", "name": "Ankyrin repeat domain-containing protein 13D", "aln": "MAGLGPTFPLHRLVWANRHRELEAALHSRKHDIEQEDPQGRTPLELAVTLGNLESVRVLLRHNANVGKESHQGWAVLQEAVSTGDPEMVQLVLQYRDFQRATQRLAGIPELLNKLRQAPDFYVEMKWEFTSWVPLVSKMCPSDVYRVWKRGESLRVDTSLLGFEHMTWQRGRRSFIFRGQEAGALVMEVDHDRQVVHTETLAPALHEPEALLAAMRPSEEHVASRLTSPIVSTHLDTRNVAFERNKCGIWGWRSEKMESVSGYEAKVYSATNVELVTRTRTEHLSDQDKLRNKGGKTPFQSFLGMAQQHSSHTLAPVQQAASPTNPTAISAEEYFDPSFSLESRNIGRPIEMSSKVQRFKATLWLSEEHPLSLGDQVTPIIDLMAISNAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARITFSNLCGCDEPVSSVCVPNSSSAISASGSP--FPCEVDPTVFEVPEGYSVLGAERSEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTVWEALTNTRPGIHPPPRVTVFEEQLQLEQ--ALQESLQLSTESRG---------PESPQKTPP-------SPAPP-------SFEEQLRLALELSSREQEELERRGQQEEDDLQRILQLSLTEH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZTN6-3", "uniprot_id": "AN13D_HUMAN", "id": "Q6ZTN6-3", "name": "Ankyrin repeat domain-containing protein 13D", "aln": "MAGPGPTFPLHRLVWANRHRELEAALHSHQHDIEQEDPRGRTPLELAVSLGNLESVRVLLRHNANVGKENRQGWAVLQEAVSTGDPEMVQLVLQYRDYQRATQRLAGIPELLNKLRQAPDFYVEMKWEFTSWVPLVSKMCPSDVYRVWKRGESLRVDTSLLGFEHMTWQRGRRSFIFKGQEAGALVMEVDHDRQVVHVETLGLTLQEPETLLAAMRPSEEHVASRLTSPIVSTHLDTRNVAFERNKCGIWGWRSEKMETVSGYEAKVYSATNVELVTRTRTEHLSDQDKSRSKAGKTPFQSFLGMAQQHSSHTGAPVQQAASPTNPTAISPEEYFDPNFSLESRNIGRPIEMSSKVQRFKATLWLSEEHPLSLGDQVTPIIDLMAISNAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARITFSNLCGCDEPLSSVWVPAPSSAVAASGNP--FPCEVDPTVFEVPNGYSVLGMERNEPLRDEDDDLLQFAIQQSLLEAGTEAEQVTVWEALTNTRPGARPPPQATVYEEQLQLER--ALQESLQLSTEPRG---------PGSPPRTPP-------APGPP-------SFEEQLRLALELSSREQEERERRGQQEEEDLQRILQLSLTEH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AHV3-1", "uniprot_id": "A0A8M3AHV3_DANRE", "id": "A0A8M3AHV3-1", "name": "", "aln": "MA--EEAFPLHYLVWNNQYLELDRELQKKKHDLERLDPRGRSALELSVCLGHLESTRVLLRHNADPTHNNTQGWTVLQEAVSTGDPELVQLVLQYRDFRRATERLAGIPELLSKLRQARDFYVEMKWEFTSWVPLVSKVCPSDVYRVWKSGSCLRVDTTLLGFEHMTWLKGRRSYIFKGGESGAMVMEVDHEKQVVYTEPLSLSPRDAPSLLAAMLPSQENTAQRLTSPIVSTHLNTRNIAFERNKSGIWGWRSEKTEVVSGYEAKVYSASNVELVTRSRTEHLSDQDKSRSKGSRTPLQSFLGIAEQHISSTGSQVSQCASPHNPTAITAEEYFDAEFNLNGRDIGRPIELTSKVQKFKATLWLSEAHPLSLAEQVTPIIDLMAISNAHFAKLRDFITLRLPPGFPVKIEIPLFHVLNARVTFSNLCGCDEPVSSVTVQSPQGATEAGETPPPLQCEVDPSVFEPPPEYTTLGPGRSEPMRDEDDNLLQFAIQQSLLDAGTESDQVTIWEALTNTRPVSQPP----LYEEDSQLERCVAIQESLSLAGGESGESDSGPPLSPSDPALSSPPCYSSLTEPRAPGAFAVASSFDEQLRLAMELSYREQEEIDRKRREEEEELERILQLSLTEK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :**** *** *:: **: *:.::**:*: **:**:.***:* **:***.********: ::. ***:************:*********::***:*********.***** *******************:********** *..*****:*******:* :****:**:* *:**:******::***:.*.*. : ::. ***** **:*:.*.***********:***:******.********* * ***********:*******:********** *.*..:**:*****:*:** * * : *.*.*** *****:.*****..*.*:.*:******::****:********* *****.:**********************************************:***********:*** * ...* *. .* : *****:*** * *:.** *.**:*****:***********:****::***:********* :** ::**: ***: *:****.*: * * .* :.* * .* **:******:*** ***** :*: ::**::*:*********:", "identical_positions": 424, "similar_positions": 118, "identity": "67.09%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101007-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZXX2-1", "uniprot_id": "A0A8I5ZXX2_RAT", "id": "A0A8I5ZXX2-1", "name": "Lysine-specific demethylase", "aln": "MADAAASPVGKRLLLLFADPTASASASAPTAAAAVSGDPGPALRTRAWRAGTVRAMS--GAVPQDLAIFVEFDGCNWKQHAWVKVHAEEVLALLLEGSLVWAPRKDPVLLQGTRVPVAQWPALTFTPLVDKLGLGSVVPVEYLVDRELRFMSDANGLHLFQMGTDVQNQILLEHAALRETVNALVSDQKLQEIFSRGPYSVQGHRVKVYQPEGEEAWLCGVVSRQDSISRLMEVSISET----GEIKSVDPRLIHVMLMDNSTPQSEGGTIKAVKSSKGKKKRESIEGRDGRRRKSASDSGCDPATKKLKGDRGEVDSNGSDGGEASR--------------GPWKGGNASGEPG-----------LEQRAKQPPSTFAPQINRSIRFATYTKENGRTLVVQD--------EPVGGDRPVPFTPYAS-------ATGQTP-LAPEVGGAENKEAGKTLEQVSQGMVA----SAAVVT---TTSSTPTTVRISDTGLASGTGPEKQKGSWSQAS--GESSRSSSLASSGFGVSLSSLSQPLTFGSGRSQSNGVLATENKPLGFSLSRSSASESQKDSDLSKNLFFQCMSQNLP----SSNYFTSGSEGVADD-------SSSRDSFRQSLES-LSSGLGKGRPVLGADTK------PGPK-AGSSVDRKVPAESMPTLTPAFPRSLLNTRTPENHENLFLQPPKLSREEPSNPFLAFVEKVEHSPFSSFASQASGSSSSATT----VTSKATPSWPESHSSADSASL-AKKKPLFITTDSSKLVSGVLGSALSTGGPSLSAMGN---GRSSSPTSSLTQPIEMPTLSSSPTEERPTVGPGQQDNPLLKTFSTVFGRHAGSFLSSPAEFAQENKAPFEAVKRFSLDERSLACRQDSDSSTNSDLSDLSDSEEQLQAKSGLKGPPEHLMGKLGPDGGRSAELLLGKGKGKQAPKGRPRTAPLKVGQSVLKDVSKVRKLKQSGEPFLQDGSCINVAPHLHKCRECRLERYRKFKEQE--QDDSTVACRFFHFRRLVFTRKGVLRVEGFLSPQ-QSDPDAMNLWIPSSSLAEG---IDLETSKYILANVGDQFCQLVMSEKEAMMMVEPHQ-KVAWKRAVRGVREMCDVCETTLFNIHWVCRKCGFGVCLDCYRLRKSRPRSETEEMGDEE---VFSWLKCAKG---QSHEPENLMPTQIIPGTALYNIGDMVHAARGKWGIKANCPCISRQSKSVLRPAVTNGISQLPSITPS----ASSGNETTFSSGGGTVATTNPEPEQAPKGAGADSRAEEPLKAEGSASNSNSELKAIR-----------------------PPCPDTAPPSSALHWLADLATQKAKEETKDAGSLRSVLSKESHSPFGLDSLNSTAKGSPLTPKLFNSLLLGPTASNSKTEGSSLRDLLHSGPGKLPQTPLDTGIPFPPVFSSSSAGAKSKASLPNFLDHIIASVVENKK--TSDSSKRSCNLTDTQKEVKEMVMGLNVLDPHTSHSWLCDGRLLCLHDPSNKNNWKIFRECWKQGQPVLVSGVHKKLKSELWKPEAFSQEFGDQDVDLVNCRNCAIISDVKVRDFWDGFEIICKRLRSEDGQPMVLKLKDWPPGEDFRDMMPTRFEDLMENLPLPEYTKRDGRLNLASRLPSYFVRPDLGPKMYNAYGLITAEDRRVGTTNLHLDVSDAVNVMVYVGIPIGEGAHD--------EEVLRTIDEGDADEVTKQRIHDGKEKPGALWHIYAAKDAEKIRELLRKVGEEQGQENPPDHDPIHDQSWYLDQILRKRLFEEYGVQGWAIVQFLGDAVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFRLTQEFRHLSNTHTNHEDKLQVKNIIYHAVKDAVGTLK--------AHESKLARS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZPY7-1", "uniprot_id": "KDM3B_MOUSE", "id": "Q6ZPY7-1", "name": "Lysine-specific demethylase 3B", "aln": "MADAAASPVGKRLLLLFADPTASASASAPTAAAVVSGDPGPALRTRAWRAGTVRAMS--GAVPQDLAIFVEFDGCNWKQHSWVKVHAEDVLALLLEGSLVWAPRKDPVLLQGTRVPVAQWPALTFTPLVDKLGLGSVVPVEYLVDRELRFLSDANGMHLFQMGTDVQNQILLEHAALRETVNALISDQKLQEIFSRGPYSVQGHRVKVYQPEGEEVWLCGVVSRQDSVTRLMEVSITET----GEVKSVDPRLTHVMLMDSSTPQSEGGTIKAVKSSKGKKKRESIEGRDGRRRKSASDSGCDPATKKLKGDRGEVDSNGSDGGEASR--------------GPWKGGNASGEPG-----------LEQRAKQPPSTFVPQINRNIRFATYTKENGRTLVVQD--------EPVGGDTPVPFTPYAS-------ATGQTP-LAPEVGGAENKEAGKTLEQVSQGMVA----SAAVVT---TASSTPTTVRISDTGLASGTGPEKQKGSWSQAS--GENSRNSSLASSGFGVSLSSLSQPLTFGSGRSQSNGVLATDNKPLGFSFSCSSASESQKDSDLSKNLFFQCMSQNVP----STNYLSRVSESVADD-------SSSRDSFTQSLES-LTSGLCKGRSVLGADTQ------PGPK-AGSSVDRKVPAESMPTLTPAFPRSLLNTRTPENHENLFLQPPKLSREEPSNPFLAFVEKVEHSPFSSFVSQASGSSSSATS----VTSKATASWPESHSSAESAPL-AKKKPLFITTDSSKLVSGVLGSALSTGSPSLSAVGN---GRSSSPTNSLTQPIEMPTLSSSPTEERPTVGPGQQDNPLLKTFSTVFGRHSGSFLSAPAEFAQENKAPFEAVKRFSLDERSLACRQDSDSSTNSDLSDLSDSEEQLQAKSGLKGIPEHLMGKLGPNGERSAELLLGKGKGKQAPKGRPRTAPLKVGQSVLKDVSKVRKLKQSGEPFLQDGSCINVAPHLHKCRECRLERYRKFKEQE--QDDSTVACRFFHFRRLVFTRKGVLRVEGFLSPQ-QSDPDAMNLWIPSSSLAEG---IDLETSKYILANVGDQFCQLVMSEKEAMMMVEPHQ-KVAWKRAVRGVREMCDVCETTLFNIHWVCRKCGFGVCLDCYRLRKSRPRSETEEMGDEE---VFSWLKCAKG---QSHEPENLMPTQIIPGTALYNIGDMVHAARGKWGIKANCPCISRQSKSVLRPAVTNGISQLPSVTPS----ASSGNETTFSSGGGAAAVTNPEPDQVPKGAGTDGRSEEPLKAEGSASNSNSELKAIR-----------------------PPCPDTAPPSSALHWLADLATQKAKEETKDAGSLRSVLNKESHSPFGLDSFNSTAKVSPLTPKLFNSLLLGPTASNSKTEGSSLRDLLHSGPGKLPQTPLDTGIPFPPVFSSSSAVAKSKASLPDFLDHIIASVVENKK--TSDPSKRSCNLTDTQKEVKEMAMGLNVLDPHTSHSWLCDGRLLCLHDPSNKNNWKIFRECWKQGQPVLVSGVHKKLKSELWKPEAFSQEFGDQDVDLVNCRNCAIISDVKVRDFWDGFEIICKRLRSEDGQPMVLKLKDWPPGEDFRDMMPTRFEDLMENLPLPEYTKRDGRLNLASRLPSYFVRPDLGPKMYNAYGLITAEDRRVGTTNLHLDVSDAVNVMVYVGIPVGEGAHD--------EEVLKTIDEGDADEVTKQRIHDGKEKPGALWHIYAAKDAEKIRELLRKVGEEQGQENPPDHDPIHDQSWYLDQILRKRLFEEYGVQGWAIVQFLGDAVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFRLTQEFRHLSNTHTNHEDKLQVKNIIYHAVKDAVGTLK--------AHESKLARS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7LBC6-1", "uniprot_id": "KDM3B_HUMAN", "id": "Q7LBC6-1", "name": "Lysine-specific demethylase 3B", "aln": "MADAAASPVGKRLLLLFADTAASASASAP-AAAAASGDPGPALRTRAWRAGTVRAMS--GAVPQDLAIFVEFDGCNWKQHSWVKVHAEEVIVLLLEGSLVWAPREDPVLLQGIRVSIAQWPALTFTPLVDKLGLGSVVPVEYLLDRELRFLSDANGLHLFQMGTDSQNQILLEHAALRETVNALISDQKLQEIFSRGPYSVQGHRVKIYQPEGEEGWLYGVVSHQDSITRLMEVSVTES----GEIKSVDPRLIHVMLMDNSAPQSEGGTLKAVKSSKGKKKRESIEGKDGRRRKSASDSGCDPASKKLKGDRGEVDSNGSDGGEASR--------------GPWKGGNASGEPG-----------LDQRAKQPPSTFVPQINRNIRFATYTKENGRTLVVQD--------EPVGGDTPASFTPYST-------ATGQTP-LAPEVGGAENKEAGKTLEQVGQGIVA----SAAVVT---TASSTPNTVRISDTGLAAGTVPEKQKGSRSQAS--GENSRNSILASSGFGAPLPSSSQPLTFGSGRSQSNGVLATENKPLGFSFGCSSAQEAQKDTDLSKNLFFQCMSQTLP----TSNYFTTVSESLADD-------SSSRDSFKQSLES-LSSGLCKGRSVLGTDTK------PGSK-AGSSVDRKVPAESMPTLTPAFPRSLLNARTPENHENLFLQPPKLSREEPSNPFLAFVEKVEHSPFSSFASQASGSSSSATT----VTSKVAPSWPESHSSADSASL-AKKKPLFITTDSSKLVSGVLGSALTSGGPSLSAMGN---GRSSSPTSSLTQPIEMPTLSSSPTEERPTVGPGQQDNPLLKTFSNVFGRHSGGFLSSPADFSQENKAPFEAVKRFSLDERSLACRQDSDSSTNSDLSDLSDSEEQLQAKTGLKGIPEHLMGKLGPNGERSAELLLGKSKGKQAPKGRPRTAPLKVGQSVLKDVSKVKKLKQSGEPFLQDGSCINVAPHLHKCRECRLERYRKFKEQE--QDDSTVACRFFHFRRLIFTRKGVLRVEGFLSPQ-QSDPDAMNLWIPSSSLAEG---IDLETSKYILANVGDQFCQLVMSEKEAMMMVEPHQ-KVAWKRAVRGVREMCDVCETTLFNIHWVCRKCGFGVCLDCYRLRKSRPRSETEEMGDEE---VFSWLKCAKG---QSHEPENLMPTQIIPGTALYNIGDMVHAARGKWGIKANCPCISRQNKSVLRPAVTNGMSQLPSINPS----ASSGNETTFSGGGGPAPVTTPEPDHVPKADSTDIRSEEPLKTDSSASNSNSELKAIR-----------------------PPCPDTAPPSSALHWLADLATQKAKEETKEAGSLRSVLNKESHSPFGLDSFNSTAKVSPLTPKLFNSLLLGPTASNNKTEGSSLRDLLHSGPGKLPQTPLDTGIPFPPVFSTSSAGVKSKASLPNFLDHIIASVVENKK--TSDASKRACNLTDTQKEVKEMVMGLNVLDPHTSHSWLCDGRLLCLHDPSNKNNWKIFRECWKQGQPVLVSGVHKKLKSELWKPEAFSQEFGDQDVDLVNCRNCAIISDVKVRDFWDGFEIICKRLRSEDGQPMVLKLKDWPPGEDFRDMMPTRFEDLMENLPLPEYTKRDGRLNLASRLPSYFVRPDLGPKMYNAYGLITAEDRRVGTTNLHLDVSDAVNVMVYVGIPIGEGAHD--------EEVLKTIDEGDADEVTKQRIHDGKEKPGALWHIYAAKDAEKIRELLRKVGEEQGQENPPDHDPIHDQSWYLDQTLRKRLYEEYGVQGWAIVQFLGDAVFIPAGAPHQVHNLYSCIKVAEDFVSPEHVKHCFRLTQEFRHLSNTHTNHEDKLQVKNIIYHAVKDAVGTLK--------AHESKLARS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BKX2-1", "uniprot_id": "A0A8M2BKX2_DANRE", "id": "A0A8M2BKX2-1", "name": "Lysine-specific demethylase", "aln": "MGDSLG-LIGKRLLLLLNDGSS--------APAATGG----EVERAAWLRGTVRAVSVIGLASPGVEVFVEFEDSPWRKRAWVQLYGDEVRVVLMESAIVWANCSDPSLSTALGSSATQWPALMFKQLIDRVGLGSVVPVEFFGARNLAFLPNGNSLHTFETEKDFTHSLLQEQPALQHAISSWHTDSELQEILRKGSYTIQGRRVKVYQPEFEQPWAFGLVSQHDPVSHIMEITMDQSCLKGEETQVVDPRVIHVMLAEGKLNESQ---------DRRKKEGDGGKGEGSRRRRTASEGDEDITLKRFKG-AGEGASDNQNGNSSNRDAEAMVTCVEMPGKGVVEGKDEAGGLGGRVTSTCSPVALSSQDSSNNSNSSQQEHSHIRSTGFVKENGSFIPNQERISSVSAVLPASTPTPPPLKPAPSPFSNTFPSLGQMPNLVPGAPAPKSSPTLPSSEREEGGVLSGYPKTAALVSPGPVTISSPSQENTSSVALTAPVDANQKPSMWGSTSEGNQTPKAPVLAPAGFGKQSCGG----VFGNVSTQTNGSSQGD-KPFGFSFRGAKDSQRQ-DSDTSQNLFFQFISQNQSNTQGQSKAFTSLSECLNKEPPSLFKSAAPSEGFKKTVVASASTGLFGSAPASGLAPLKEQPKVPDIKPAGNGILMNKPFGAVGEAQSKLPATFSSAIIQAASSTEVLKPSGLGTSGLGNASGGIRNVNSSTPVSSFGLLAGNKVSDGHENLFLQPSKETNSFLAYGRGVPQTPFGALTSPKSSSAQSASAVSPSGSTSLLGQDPPGSDAKPNLFTMAEPPKGILAPQFAAPALMTTPS----FTSVAQDGQQISKPNREGSDDSSGTLLSTEAEGVS---VPFEQSK-FSLEERLQSIKKDSESSSNSDLSDLSEGED----NAGQSQKPDLPAGNED------------KNKAQAAAKSRPRSKPFKVGQSVLKDQNKVRRLKQSGEAFLQDGSCINVAPHLHKCRECRLERYRKSREQDSDDDDPNVACRFFHFRRLAFTKKGVLRVEGFLSPQ-QSDSMAMGLWLPSITIQEG---LDLDTSKYILANVGDQFCQLVMSEKEAMMMVEPHQ-KVAWKRAVRGVREMCDVCETTLFNIHWVCRKCGFGVCLDCYRLRKNRP-PEVEDGPEEE---VFSWLKCAKG---QPHEPQNLMPTQIIPGTALYSIGDMVHAARGKWGIKANCPCTSR-HKTLMRPSAPNGLSQSGAAHSSGNGTTSTSSTTRPNEESAAGVVVKTEPVEEPTSADTTSSTSGTNSSTSSPAPAPTSAPTLLPPSLPPPSLPPPSLPPAPALVPTPPAKDSKSSSSALHWLADLATQKEPKE-----SLRSMMGRDSRSPFGLDSFSTLSKPSGSSPKLFNSLLLGAGPSQPKAEGTSLRDLLNSGSGKLPQGPTEGGVPFPPVFSTASQADKMKGGLPNFLDHIIASVVETKKSEVRRASGSAEVIESATAPRREGVMGLSVLDPHTSHSWLCDGRLLCLQDPSNPNNWKIFRECWKQGQPVLVSGIHRKLKEHLWRPEAFSEEFGDQDVDLVNCRNCAIISDVKVREFWDGFQVISKRLQGSDGQPMVLKLKDWPPGEDFRDMMPTRFNDLMDNLPLPEYTKRDGRLNLASRLPNFFVRPDLGPKMYNAYGLISTEDRKVGTTNLHLDVSDAVNVMVYVGIPEGENDQESEADLAGFKEVMQTIEEGDVDDMTKRRVYEIKEKPGALWHIYAAKDAEKIRELLRKVGEEQGQENPPDHDPIHDQSWYLDQTLRRRLYEEYGVQGWSIVQFLGDAVFIPAGAPHQVHNLYSCIKAAEDFVSPEHVKHCFRLTQEFRHLSNTHTNHEDKLQVKNIIYHAVKDAVATLK--------AHEPKLGRS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHC5-1", "uniprot_id": "KDM3_DROME", "id": "Q9VHC5-1", "name": "Lysine-specific demethylase 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSQKELAALVATRTSRKRTISSTSFSISTR------TDPKSIIEIHIFN------------------DSLPIKRACCEVENPT------------------------LKAEQR---VQQEEESLG--QVPPLTEEEQ-------------------------------------------QRHDEFRNSGSIFLQDLPCFKLQQAQP--------IAGSSPIPKCRECRRRNLATTEGEP--SSVSDVYCRFYEFRRLQFNENGELCVVGFPNPYSEPSPEDIAIWQPDKNTPPTSGYMDIQVCRYILLHAGDQFCYIWHQEAEALSLHQNTDGTIAWKKAVKGTREICDVCDTTLFNYHWTCRKCGFGVCLDCVKDRKEGLRLRRAENAAQKGCDEYHWLLCSDPSGPQEHVLTELMLTQIIAGDALNVLGRLLHEVRTLWQVPQVCGCLLS------KQAIEDAQS---------------------------------------KEVIQDMIKESQLKQHTSYSSLASEQKVHQ-----------------------------------QQRLDQLHATK----------------LEFARELGVDYVPG---------RVWTKETLGKDPITTAFDNLKHINFLRKG----------------------------LAGLRRFLPPRTMTFAYSTQ-----------------------------LAPGVPHEFLCDGRLLRLTDAMHPDNRVLFQEVWKCGQPVMISEVARSLNLDLWHPQAFCRDFGDKPNDLINCLNGNLVPNQPMRHFWEGFQCMTKRLPDAYGKPMLLKLKDWPPGDDFAEILPTRFADLMKGLPMPEYTLRTGNLNIASCLPKMFVPPDLGPKMYNAYGSALHPDK--GTTNLHLDISDAVNIMVYVGIPQDGDTRP------QMAATQKAIEIGGCDYITRARCQSPDVLPGALWHIFPARDADKIRDLLNRVTLEKGFRLEPDHDPIHDQNWYLDDKLRARLFKEYGVEGHPIVQCLGDAVFIPAGAPHQVQNLHNCIKVAEDFVSPENITHCYHLTHEFRRLSHSHTNHEDKLQIKNIIYHAIKDCCTILTRAVDERLNAELTKLNAD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 335, "similar_positions": 238, "identity": "17.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101007-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P59997-1", "uniprot_id": "KDM2A_MOUSE", "id": "P59997-1", "name": "Lysine-specific demethylase 2A", "aln": "-------------------------------------------------------------------MEPEEERIRYSQRLRGTMRRRYEDDGISDDEIEGKRTFDLEEKLQTNKYNAN-FVTFMEGKDFNVEYIQ--------------------RGGLRDPLIFKNSDGLGIKMPDP-----DFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPE-EEREKLYNVISLEFSHTRLENMVQWPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLISVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLT------------------------------------KDFQKESLSMDMELNELES---GNGDEEGVDREARRMNNKRSVLTSPVANGVNLDYDGL--------------GKACRSLPSLKKTLSGDSSSDSTRGSHNGQVWDPQCSPKKDRQVHLTHFELEGLRCLVDKLESLPLHKKCVPTG-IEDEDALIADVKILLEELASSD------PKLALTGVPIVQWPKRDK--LKFPTRPKVRVPTIPITKPHTMKPAPR---------LTPV-RPAAASPIVSG---ARRRRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCGEV----------DQNEETQDFEKKLMECCICNEIVHPGCLQ---------MDGEGLLNEELPNCWECPKCYQ------EDSSDKAQKRKIEESD-----------EEAVQAKVLRPLRSCEEPLTP-----------PPHSP----------------------------TSMLQLIHDPVSP-------RGMVTRSSPGAGPSDHHSASRDERFKRRQLLR--LQATER----------TMVRE------------------KENNP---SGKK--------------------------ELSEVEKAKIRG--SYLTVTLQRPTKELHGTSIVPKLQAITAS-------SANLRPNPR-----VLMQHCPARNPQHGDEEGLGGEEEEEEEEEE-DDSAE---EGGAARLN-------GRGSWAQD-------------GDESWMQREVWMSVFRYLSRKELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIRDLLTPPTD-KPGQDN-RSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLFFLRRIANVTLIDLRGCKQITRKACEHFIS----DLSINSLYCLSDEKLIQKIS-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ARD6-1", "uniprot_id": "A0A8I6ARD6_RAT", "id": "A0A8I6ARD6-1", "name": "[histone H3]-dimethyl-L-lysine(36) demethylase", "aln": "--------------------------------------------------------------------------VGREEGKRGTMRRRYEDDGISDDEIEGKRTFDLEEKLHTNKYNAN-FVTFMEGKDFNVEYIQ--------------------RGGLRDPLIFKNSDGLGIKMPDP-----DFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPE-EEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYSIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLT------------------------------------KEFQKESLSMDMELNELES---GNGDEEGADKEARRMNSKRSVLTSPVANGVNLDYDGL--------------GKACRSLPNLKKTLSGDSSSDSSRGSHNGQVWDPQCSPRKDRQVHLTHFELEGLRCLVDKLESLPLHKKCVPTG-IEDEDALIADVKILLEELASSD------PKLALTGVPIVQWPKRDK--LKFPTRPKVRVPTIPITKPHTMKPAPR---------LTPV-RPAAASPIVSG---ARRRRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCGEV----------DQNEETQDFEKKLMECCICNEIVHPGCLQ---------MDGEGLLNEELPNCWECPKCYQ------EDSSEKAQKRKIEESD-----------EEAVQAKVLRPLRSCEEPLTP-----------PPHSP----------------------------TSMLQLIHDPVSP-------RGMVTRSSPGAGPSDHHSASRDERFKRRQLLR--LQATER----------TMVRE------------------KENNP---SGKK--------------------------ELSEVEKAKIRG--SYLTVTLQRPTKELHGTSIVPKLQAITAS-------SANLRPNPR-----VLMQHCPARNPQRGDEEGLGGEEEEEEEEEE-DDSAE---EGGAARLN-------GRGSWAQD-------------GDESWMQREVWMSVFRYLSRRELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIRDLLTPPTD-KPGQDN-RSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLFFLRRIANVTLIDLRGCKQITRKACEHFIS----DLSINSLYCLSDEKLIQKIS-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Y2K7-1", "uniprot_id": "KDM2A_HUMAN", "id": "Q9Y2K7-1", "name": "Lysine-specific demethylase 2A", "aln": "-------------------------------------------------------------------MEPEEERIRYSQRLRGTMRRRYEDDGISDDEIEGKRTFDLEEKLHTNKYNAN-FVTFMEGKDFNVEYIQ--------------------RGGLRDPLIFKNSDGLGIKMPDP-----DFTVNDVKMCVGSRRMVDVMDVNTQKGIEMTMAQWTRYYETPE-EEREKLYNVISLEFSHTRLENMVQRPSTVDFIDWVDNMWPRHLKESQTESTNAILEMQYPKVQKYCLMSVRGCYTDFHVDFGGTSVWYHIHQGGKVFWLIPPTAHNLELYENWLLSGKQGDIFLGDRVSDCQRIELKQGYTFVIPSGWIHAVYTPTDTLVFGGNFLHSFNIPMQLKIYNIEDRTRVPNKFRYPFYYEMCWYVLERYVYCITNRSHLT------------------------------------KEFQKESLSMDLELNGLES---GNGDEEAVDREPRRLSSRRSVLTSPVANGVNLDYDGL--------------GKTCRSLPSLKKTLAGDSSSDCSRGSHNGQVWDPQCAPRKDRQVHLTHFELEGLRCLVDKLESLPLHKKCVPTG-IEDEDALIADVKILLEELANSD------PKLALTGVPIVQWPKRDK--LKFPTRPKVRVPTIPITKPHTMKPAPR---------LTPV-RPAAASPIVSG---ARRRRVRCRKCKACVQGECGVCHYCRDMKKFGGPGRMKQSCVLRQCLAPRLPHSVTCSLCGEV----------DQNEETQDFEKKLMECCICNEIVHPGCLQ---------MDGEGLLNEELPNCWECPKCYQ------EDSSEKAQKRKMEESD-----------EEAVQAKVLRPLRSCDEPLTP-----------PPHSP----------------------------TSMLQLIHDPVSP-------RGMVTRSSPGAGPSDHHSASRDERFKRRQLLR--LQATER----------TMVRE------------------KENNP---SGKK--------------------------ELSEVEKAKIRG--SYLTVTLQRPTKELHGTSIVPKLQAITAS-------SANLRHSPR-----VLVQHCPARTPQRGDEEGLGGEEEEEEEEEEEDDSAE---EGGAARLN-------GRGSWAQD-------------GDESWMQREVWMSVFRYLSRRELCECMRVCKTWYKWCCDKRLWTKIDLSRCKAIVPQALSGIIKRQPVSLDLSWTNISKKQLTWLVNRLPGLKDLLLAGCSWSAVSALSTSSCPLLRTLDLRWAVGIKDPQIRDLLTPPAD-KPGQDN-RSKLRNMTDFRLAGLDITDATLRLIIRHMPLLSRLDLSHCSHLTDQSSNLLTAVGSSTRYSLTELNMAGCNKLTDQTLIYLRRIANVTLIDLRGCKQITRKACEHFIS----DLSINSLYCLSDEKLIQKIS-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PZC6-1", "uniprot_id": "A0A8M1PZC6_DANRE", "id": "A0A8M1PZC6-1", "name": "[histone H3]-dimethyl-L-lysine(36) demethylase", "aln": "---------------------------------------------------------------------MSEAKSRYSKRLRSGTRRRYQDDGISDDEIEGKRSFDLEEKLQSDRYNSN-LVKIMDGKDFTLEYIQ--------------------REGLRDPIIFKKADGLGIKMPDP-----DFSVSDVKLFVGSRRMIDVMDAATQKGIEMSMGQWRRYYETPA-SQREKLYNVISLEFSHTKLEHLVKRPTSVDMIDWVDNMWPRHLKERQRDSTNAITDMQYPKVQKYCLMSVEGCFTDFHIDFGGTSVWYHIHKGGKVFWLIPPTPQNLELYENWVLSAKQGDIFLGDKASMCQRIELKQGYTFMIPSGWIHAVYTPMDTLVFGGNFLHSFNIPMQLNIFNIEDRTRVPSKFRYPFYFEMCWYVLERYLYCLTNTSHLT------------------------------------PEFQKHSLGIGLKKEDVIKPAKPDGDSESEDEEVVKEEPEEEAVTPPARPGV---------------------------------------------------------------KVHLAPFELEGLWALLHKLEDLPAHKKCVPAG-IRNAPALLSDIRKLLEEHANDN------PKLSYTGKPIVKWPKRPS--WYQPPPP---PPPSHLYRPRAPGSGPM---------LAPVPRPVKPSSSISA---LRRRRVRCKRCEACLRTECGNCNYCRDMRKFGGPGRLKKSCVLRQCLAPALPLTAVCVICKEG----------NQESDDTESVQMLMECSECAQITHPECIK---------VPGEGVINKDLPSCWECPKCVQGKKTESSSSSEEETDSSVSNSSRLSGPPAKRAYREGIGVEGLRIARRGRSSISPSSLPITRSRRQPPPSQRLLLQHQQNRKRAGALELQLRKRIKLERNKILQSTRSPVSLSPKLLRQRSLERRGLIRAGPGQSLSRGRGSSSFRGRGLR--VRGGGRGGGLRERMEMAVEREDSAEEEQQERKENGQYNGKENRPQRLSGKAGEDENGDAHRNGESEESSEGGEPTLSDTSAALTDDVRGQESCVTVKLQPSRAKRDPSTIVPKLEANLSSRSLPPSHKALLRPPLRNGARCSDAPHSPADRLHVNKSHALSSSSHTLTRRASKNSNLRSNFEDSTHRLTRERIQKNARSERAKSSDSCPSSTFHSGGGNEPGWEKEVWVSVFRYLTRAELCVCMAVCKSWYKWGCDKRLWTRISLSRSRSMSPQVLTGIIKRQPVTLDLSWANITKKQLSWLINRLPGLKDLVLSGCNWSSVSALSSPSCPLLRSLDLSWADGIKDAQIRELLNP-----PGSDN-RSQMKNMQCLWLCGLEVTEATLRLIIRHMPLLTRLELSRCP-ITDGALNLLSAVGSSTRNTLTHLNLAGCTQLTDRCLVYLRRLSCLSILDLRDCKGVSVQACQSFIS----ELSVNTLYYLSDDKLIERIS-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VHH9-1", "uniprot_id": "JHD1_DROME", "id": "Q9VHH9-1", "name": "JmjC domain-containing histone demethylation protein 1", "aln": "-----------------------------------MSTAVETGSSPAKSNSNNSSSGGNNNNGNGNLSPNAKGVQRRQLRERKQRKLYLEEWSLGDEDGEGTRGFSVAEKLESSKFAQAGMVREMRGCDLTVAFLQ--------------------QHGFNIPLLFRDKAGLGLRMPDPQ----EFTVNDVRLCVGSRRLLDVMDVNTQKNLQMTMKEWQQYYDSP---QKDRLLNVISLEFSHTRLDRFVQSPEIVRQIDWVDVVWPKQLKDAQREGTNLLGGMMYPKVQKYCLMSVKNCYTDFHIDFGGTSVWYHILRGSKVFWLIPPTDRNLQLYEKWVLSGKQADIFFGDTVEKCARVYLTAGNTFFIPTGWIHAVYTPTQSLVFGGNFLHSFGIVKQLKTASVEDSTKVPQKFRYPFFTEMLWYVLARYVHTLLGHSHLEGEASLSEDEMAARPHTHLTHHELFGLKEIVMYLYDLPPQKKNVPSLVLDPVALIKDVRSLVERHCKDQQDLAITGVSVLKSPPGSQPPFLLYDRTRVKQEIKQEIARKNAEVIREQQQLEAGRAREAESDTSQSTGVGSVIGMGAGVEYSNGVMKKEQLENGSGVTVGGHGSQPEATFALPTDTLKYRPPKKMHLATALVAAAASSSSGGGGPVAGVGGSAVVGSSHSPTGGGVGPVTGAGGAISVIATSSSYIEGGQVGGILNMDNCHSPEGGGAKLSPNLTGTGQPRRRRTRCKNCAACQRSDCGTCPFCMDMVKFGGPGRAKQTCMMRQCLSPMLPVTAQCVYCHLDGWRQTPVSPQTKQLASADGPSALMECSVCYEIAHPDCALSQLDGTEDAADAKGIVNEDLPNSWECPSCCRSGKNYDYKPRHFRARQKSSEVRR----------VSVSHGQGGAEGHADGNTLLP-----------PPVGQYN----------------------DFVFTSESEMESGTVSG-HMTHWKHGMKRHHQLEVKTERNNSCDTPSPGISPNAIGGDSKVGKRRKSDDGTSVSSSMHE------------------SNDAPCGSSAEGAGG----------------------AGNANVSTNQWSGSGGGGGSRKKNSIRSQLAQQMLNSSTRVLKKP------QYVVRPASG-----TGSSSSSGNGGSASATNGISNGSNQSGANSCGAGNGERGTNNGGLSGS------NGLGNQHYSS------------SQNLALDPTVLKIIFRYLPQDTLVTCCSVCKVWSNAAVDPDLWKKMNCSEHK-MSASLLTAIVRRQPEHLILDWTQIAKRQLAWLVARLPALKNLSLQNCPIQAVLALHTCLCPPLQTLDLSFVRGLNDAAIRDILSPPKDSRPGLSDSKTRLRDLKVMKLAGTDISDVAVRYITQSLPYLRHLDLSSCQRITDAGVAQIGTSTTATAR-LTELNLSACRLVSENALEHLAKCEGLIWLDLRHVPQVSTQSVIRFASNSKHDLCVRDIKLVERRRRNSTTANRSWHHD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40034-1", "uniprot_id": "JHD1_YEAST", "id": "P40034-1", "name": "JmjC domain-containing histone demethylation protein 1", "aln": "MQDPNICQHCQLKDNPGALIWVKCDSCPQWVHVKCVPLKRIHYSNLTSSEVLSYPNSAKQIKSYRCPNHKEGEYLTAYALITQKGKRQRNKENPEDSHINKRYNFRKKKLLDYIALNEGESKRDKMNHPHKESFMKSFEKWKNGSNIINAADFAEKFDNIDVPYKIIDPLNSGVYVPNVGTDNGCLTVNYITEMIGEDYHVDVMDVQSQMNENWNLGSWNEYFTNTEPDRRDRIRNVISLEVSNIEGLELER-PTAVRQNDLVDKIWSFNGHLEKVNGEKAEENDPKPKVTKYILMSVKDAYTDFHLDFAGTSVYYNVISGQKKFLLFPPTQSNIDKYIEWSLKEDQNSVFLGDILEDGIAMELDAGDLFMIPAGYIHAVYTPVDSLVFGGNFLTIRDLETHLKIVEIEKLTKVPRRFTFPKFDQVMGKLCEYLALD------------------------------------------------KNKITSDVSDGDLLS-----------RTTNCAIQSLHAYVIKP--------------------------------------------------------------------EVKYKPLNFTSKKHLAKALADLIS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. . *.. : * : *. . . ::: .: * : . . *: :*: ::*. : :*. :****. :* . : .: .* .*: .. .:::: ******.*: . .: : * * * ** :*. : : : :. : *** ** *:**...:****:**.****:*:: * * * *:*** *:: * :* *. .* .:*:** . : * * *.**:*:******* ::******** .: :*: .:*. *:** :* :* : :: : *. :. : . * * . . ", "identical_positions": 93, "similar_positions": 106, "identity": "6.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101011-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIR4-1", "uniprot_id": "CCD33_RAT", "id": "Q5XIR4-1", "name": "Coiled-coil domain-containing protein 33", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MG--RQKTKVPEEPQDRLDTSLDPYPDTNYLAPCNKETVMVTLYGATNLPTCKDSSEPWPYVVVKTTSEEANNHSPQARTSVTSEPTRAPIWGDTVNVEIQAEDTGREDVTLKVMDSNKKEELVSYEIPIKYLRAFHPYHFELKKNE---KEDEATAKTRLYATVVRKGSLLPRYIGYDHTALEVFLRGVNEPLVNNPSPMVVIARVVPSYTEFKARKARQDPASVGLPLTQVSFPISSPMTFDVPRVSQNGCPQLSKPGGPPEQPLWNQSFLFLGRDGATSFSEDTALVLEYYPSASMKSSEPWTLNQPLGVSVLPLKSHLYRKMLTGKGLKGLQVERLPIFDTNLKTINGEAPSVNLAFQLLSSERPENFLTPNNSKTLPTLNPKILDENLGAIRESWSVSSLDSSQEAEELQP-------------RDVEMNNYRRAMQKMAEDILALRKQANILEEENRMLR----------SHLTQQSIEEEQNRAEEENLAVSMKQRLLLNELDMKRLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAAQLRRYQDKLQKMKGLEDTVRHQEKVIEKMEQILEERLHERKEPAPSNRPQGKPIMDAFAPQASGIPLGPAGENLAMDLYSMLLAENTRLRTELEKNRQQSAPIILQQQALPVDPGELGAGGDLAERLQDTNGPGHSKYTETMPA-----------------------------------QDFLGGTSDKFSLLAKLEQAQSRILSLENQLEESARHWAREKQNLAIRLQEQQHGFGQSPNSIIVDQPHFARSQGSTTPRQNLKDEGYPGNIERPLQTHLTPGTRDIRHHLR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3ULW6-1", "uniprot_id": "CCD33_MOUSE", "id": "Q3ULW6-1", "name": "Coiled-coil domain-containing protein 33", "aln": "MAFRGPDPYLPASLLSQRLKAGEKTLDLEFEILSVGFNEEGRYALRLSAENPLQAGSSAGVQLQVNDGDPLPACSAVTEVIEQQDPGQSLTFTRNKFIFTLPKGFCKNDGQSDAHLRVEALRLDGSSGQEAQRVGEAIFPIYPRPDEPRMNLTAQDHEDLYRYCGNLALLRASEDPTARHCGGLAYSVAFHVHRDPRSSVSDCQLEPSQPELQTSREALSDKIEESYMSPFSTDSDQEGLSWEAGPWQHPAQVPEEPQGRLDTSQDPYPAANYLAPCNKETITVTLYGATNLPAGKDGSEPWPYVVVKTTSEKANKHSPQAMTSVTSEPTRAPVWGDTVNVEIQAEDTGREDLILKVMDNKRKKELVSYDIPIKYLRIFHPYQFKLEK---------------------------------------VFLRGVNEPLVNSLKPMVVIARVVPNYTEFKARQARRDPASVGLPLTQVSFPISSPMNFDVPRINQNGYPQLSKPGGPPEQPLWNQSFLFQARDGATSFSENTALVLEYYPSASMQSSEPWALNQPLGVSVLPLKSRLYHKMLTGKHLQGLQVERLPIM------------------------RPENFLTPNNSKALPTINPKILDENLGAIRESWSMSSLDSAQEVEELQP-------------RDVEMNNYRRAMQKMAEDILALKKQANILEEENGMLR----------SHLSQQSIEE-QSRAEEENLAVSMKQKLLLNELDMKRLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAAQLRRYQDKLQKMKALEDTVRHQEKVIEKMEQILEERLCERKEPIPSNRPQGKPIM------ASGIPLGPMGETLAVDLYSMLLAENTRLRTELEKNRQQSAPIILQQQALPVDPRELGAGGDLAERLQDTNGPGHPKSTETLPAQVGVPGGYSTAQAAPGAPAVHKPKINIWSSGGMRTQDFLGGTSDKFNLLAKLEQAQSRILSLENQLEESARHWAREKQNLAIRLQEQQHGFGQPPNSIIIDQPNAG---ASKNPQQLSKLEPSLPSSDKKLN-RPSDSQIEISNNQKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N5R6-1", "uniprot_id": "CCD33_HUMAN", "id": "Q8N5R6-1", "name": "Coiled-coil domain-containing protein 33", "aln": "MAFRGPEPWVSASLLRQRLKAEEKTLDLEFEVLSVGFNEAGRYALRLSAENPLQVGSGAGVQLQVNDGDPFPACSAITDVIEQQEPGQSLTLTRSKFIFTLPKGFCKNDGQHDAQLHVEALRLDEPLGRAAQRVGEAIFPIYPRPDQPRMNPKAQDHEDLYRYCGNLALLRASTDPTARHCGSLAYSVAFHVHRGPQPPVSDSPPR-------------------------------------AG--QPELMSPEEP---LIASQSTEPEIGHLSPSKKETIMVTLHGATNLPACKDGSEPWPYVVVKSTSEEKNNQSSKAVTSVTSEPTRAPIWGDTVNVEIQAEDAGQEDVILKVVDNRKKQELLSYKIPIKYLRVFHPYHFELVKPTESGKADEATAKTQLYATVVRKSSFIPRYIGCNHMALEIFLRGVNEPLANNPNPIVVIARVVPNYKEFKVSQANRDLASVGLPITPLSFPIPSMMNFDVPRVSQNGCPQLSKPGGPPEQPLWNQSFLFQGRDGATSFSEDTALVLEYYSSTSMKGSQPWTLNQPLGISVLPLKSRLYQKMLTGKGLDGLHVERLPIMDTSLKTINDEAPTVALSFQLLSSERPENFLTPNNSKALPTLDPKILDKKLRTIQESWSKDTVSSTMDLSTSTPREAEEEPLVPEMSHDTEMNNYRRAMQKMAEDILSLRRQASILEGENRILR----------SRLAQQEEEEGQGKASEAQNTVSMKQKLLLSELDMKKLRDRVQHLQNELIRKNDREKELLLLYQAQQPQAALLKQYQGKLQKMKALEETVRHQEKVIEKMERVLEDRLQDRSKPPPLNRQQGKPYTGFPMLSASGLPLGSMGENLPVELYSVLLAENAKLRTELDKNRHQQAPIILQQQALP---------------------------------------------------------------------DLLSGTSDKFNLLAKLEHAQSRILSLESQLEDSARRWGREKQDLATRLQEQEKGFRHPSNSIIIEQPSALT--HSMDLKQPSELEPLLPSSDSKLNKPLSP-QKETANSQQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IYE9-1", "uniprot_id": "A0AC58IYE9_DANRE", "id": "A0AC58IYE9-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNDWFVSCSAYKSCQAGFLCCGNPTSGCQHCQSFLFIQLFNMPDRSSETFSHMQNPEKPQNDPAG--AQINMDSYDFPSHDAISQILQEYLQLKSPK-TQTRTESVPQ--------------------------------------------------------------KKANSQLNRTFDVNLAHKSP----PASDLKDESHNGEVSEHQT---------------KELENYSAALHKMAEDMIGLRSQMRVLESENSDLRRELSLHQDLGRTLLDDTDVDVMTNTEIADRIASLKFKLSSESSKASAMKDRIQQLQNELIKKNDIEKEFVQLQRAHQQQQAVLKRYQTRDKKITALEDTVRQQEKVIEKMEKLLDANLKERRKGNSEKKKAAMKQKD--------------EEEKRREIESVFVAENSRLREELDRLCNLPPPIIIQQPAQS--------------------------------------------------------------------LYQPFSDSEKLELLTQLARAEGQIQTLEQQLKENAKLWGKEKQEMLTRVSEYERGFARTSAMILHDLPVQMP----FQPQPISGKHPHNTHTLWTI-----------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . :* :* .. . . .: *::* ..: .::.:* * ::* : : . .*.. : :: ** * : ::. : . * . **: *:: :: .:. : . . . : . . *::** *::*****::.*: * :** ** ** * :: : .:. : .*:* :* .. . . ::**:*:******:*** ***:: * :*:* * * *::** : :*:..**:***:*********::*: .* :* : . :: . * :: *:::***::** **:: : .***:** * . . *:*:.**::* :*:.:* :**.**::.*: *.:***:: *:.* ::** :.. *: : * : . : ", "identical_positions": 114, "similar_positions": 151, "identity": "10.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101013-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AFI6-1", "uniprot_id": "A2AFI6_MOUSE", "id": "A2AFI6-1", "name": "Transmembrane 9 superfamily member", "aln": "MVVPEAGFKMGLSGRRVETKLCPGLHGLKWWLLLCFLATTCDAFFFPGLVPVTYCEEGHP--NSYCKSSIQVYADKLYSVDSVMFYDYDSFDFCQDSLKRTPSETLGQILFGEQVTSCPYKFSFNKDETCRKVCVKSYAPDNEDDMNKLAFLKKGIKQDYRHHWIVDNTGIIWCYDTENEEHHCMSGFPIGCFNAPSDQVKGSCLINPEFNKNNSLYLFNHLDITITYHIESDTTVKVAKLISSRVDPKSYKHLDEDHLTCNEPPMEIPEEDTENLNVIYTYSVKFEESKATEWSSEGDYDLDSTAETSLQWIRLVNSFFVVLFLCGLVVILLLRSIWRDIAKFNR------IKIS-----VYDRR--LFGWRLIHGNLFRLPEHGMLLSILLGQGTQVFIMTFLSLFLAGLGFLTPADQNVLVNYGVVLWLALEIPAGYMSAKMYKTFKGINWKMHFLLTTVLFPGIVFADIFIMNLILWMDGSPAAISFCTLASLFALYFGVSTPLTFLGVYFG-KREKFEFPVYAPKHEHGSPQRTFFPKSTITIILGSLLPFGCIFLQLSYILNRIWSPHMYYLFAFLLLLFLIFMISCSEVTVLLCYFRLCAEDRGWWWRAFLTSSFTSAYIFIYVIHYFFTKLQVTSIGSTFMYFGYAFILVLAFFLFTGTIGFFSCFFFVTTIYGVIKED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2R8Q6R8-1", "uniprot_id": "A0A2R8Q6R8_DANRE", "id": "A0A2R8Q6R8-1", "name": "Transmembrane 9 superfamily member", "aln": "---------------------MKSLKPHCIFLLSLTIVNSSFAFYLPGLAPVNFCKKSSTGDAEECQHEIQLFVNRLDSVESVLPYEYDAFDFCKDTNERRPTENLGQVLFGERIETSPYKFLFMNDLTCQKVCTKSYNTTSAVERLKLDFLKRGMDLNYQHHWIVDNMPVTWCYIVEGDQKICNPGFPIGCLVNQEGTPKDACVINADFNKKNTFYVFNHVDINIVYHSGDETTGMAARLVGATLEPRSIMHSDHEKPSCEGPPMEIPYEFNSNFKMTYTYSVTFTQNNAIRWASRWDYILVSMPHTNIQWFSISNSLVIVLFLSGMVAMIMLRTLHKDIARYNQLDQADWVKIPPGANITYEEAQEESGWKQVHGDVFRAPRMGMLLSVFLGQGTQIFTMTFITLFLACLGFLSPANRGALMTCAVVLWVLLGTPAGYVSSRLYKTFGGEKWKTNVLLTAFLCPGIVFVDFFLMNLILWTEGSSAAVPFGTLVAILALWFGISVPLTFVGAYFGFKKPGIEPPVRTNQIPRQIPQQSFFTKPVPGIIMGGILPFGCIFIQLFFILNSIWSHQMYYMFGFLFLVFIILVITCSEATVLLCYFHLCAEDYNWWWRSFLTSGFTAVYLFVYAVHYFFSKLQIIGAASTILYFGYTLIMVLIFFVFTGTIGFFACFFFVNKIYSVLKVD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*: :** :..:. **::***.**.:*::. . . *: .**::.::* **:**: *:**:****:*: :* *:*.***:****:: :.**** * :* **:***.*** . . : ** ***:*:. :*:******* : *** .*.::: * .******: .. *.:*:**.:***:*::*:***:**.*.** .:** .*:*:.: ::*:* * *.:: :*: ****** * ..*::: *****.* :.:* .*:*. ** * * ..*.:**: : **:.:****.*:*.:::**:: :***::*: :**. .*:. **: :**::** *. *****::******:* ***::**** ****:**::..*:. .****: * ****:*:::**** * :** :.***:.* *****.*:*:****** :**.**:.* **.:::**:**:*.****:*.*** *: :* ** : : : **::**.*.. **:*.:*******:** :*** *** :***:*.**:*:*:*::*:***.*******:***** .****:****.**:.*:*:*.:****:***: . .**::****::*:** **:********:*****..**.*:* *", "identical_positions": 331, "similar_positions": 219, "identity": "48.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101013-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XXR3-1", "uniprot_id": "ARHG6_RAT", "id": "Q5XXR3-1", "name": "Rho guanine nucleotide exchange factor 6", "aln": "----------------------------------------MNPEERVVTWLIS-----LGVLESPKKTICDPE-----------EFLKSSLKNGVVLCKLISRLLPGSVEKYCQEPQTEADCIDNINDFLKGCATLQVEVFEPDD------LYSGANFSKVLNTLLAVN----------KATEDQLSERPCGRSSSLSATTSSQTNPQAAVPSTTPEQQSEEKAAEMTENGS---------HQLIVKARFNFKQTNEDELSVCK--------------GDIIYVTRVEEGG--------------------------WWEGTLNGR----TGWFPSNYVREIKPSERPLSPKAVKGFDTAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEFTCLLGNFEEVCTFQQTLCQALEECSKSPENQHKVGGCLLNLMPHFK------------------------------SMYLAYCANHPSAVNVLTQHSDDLERFMENQGASSP-----------GILILTTSLSKPFMRLEKYVTLLQELERHMEDTHPDH----------QDILKAIIAFKSLMGQCQDLRKR---------------------------KQLELQILSEPIQAWEGDDIKTLG------------NVIFMSQVVMQHGACE--------------------------EKEERYFLLFSSVLIMLSASPRMSGFMYQGKVPIAGMVVTR-LDEIEGNDCTFEITGSTVERIVVHCNNNQDFQEWMEQLNRLTKG-------------PASCSSLSKTSSS--------------------SCSTHSS-FSSTGQPRGPLEPPQ------IIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKT-------------------------------------------------MKKFLH-----------------------------------------------------KRKTERKTSEEEYVIRKSTAALEEDAQILK--------------------VIEAYCTSASFQQG-----------------------------------------------TRKDSVPQVLLPEEEKLIIEETRSN-----------------------------------------------------------------GQTIIEEKSLVDTVYALKDEVKELKQENKKMKQCLEEELKSRKDLEKLVRKLLKQTDESIRAESSSKTSILQ-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K4I3-1", "uniprot_id": "ARHG6_MOUSE", "id": "Q8K4I3-1", "name": "Rho guanine nucleotide exchange factor 6", "aln": "----------------------------------------MNPEERLVTWLIS-----LGVLESPKKTVCDPE-----------EFLKSSLKNGVVLCKLINRLLPGSVEKYCLEPQTEADCIDNINDFLKGCATLQVEVFEPDD------LYSGANFSKVLNTLLAVN----------KATEDQLSERPCGRSSSLSAATSSQTNPQVAVPSTAPEQHSEEK-AEMTENGS---------HQLIVKARFNFKQTNEDELSVCK--------------GDIIYVTRVEEGG--------------------------WWEGTLNGR----TGWFPSNYVREIKPSERPLSPKAIKGFDTAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEFTCLLGNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLNLMPHFK------------------------------SMYLAYCANHPSAVNVLTQHSDDLERFMENQGASSP-----------GILILTTSLSKPFMRLEKYVTLLQELERHMEDTHPDH----------QDILKAIIAFKTLMGQCQDLRKR---------------------------KQLELQILSEPIQAWEGDDIKTLG------------NVIFMSQVVMQHGACE--------------------------EKEERYFLLFSSVLIMLSASPRMSGFMYQGKIPIAGMVVNR-LDEIEGSDCMFEITGSTVERIVVHCNNNQDFQEWMEQLNRLTKG-------------PTSCGSLSKTSSS--------------------SCSTHSS-FSSTGQPRGPLEPPQ------IIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKT-------------------------------------------------MKKFLH-----------------------------------------------------KRKTERKASEEEYVIRKSTAALEEDAQILK--------------------VIEAYCTSASFQQG-----------------------------------------------TRKDSVPQVLLPEEEKLIIEETRSN-----------------------------------------------------------------GQTIIEEKSLVDTVYALKDEVKELKQENKKMKQCLEEELKSRKDLEKLVRKLLKQTDECIRSESSSKTSILQ-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15052-1", "uniprot_id": "ARHG6_HUMAN", "id": "Q15052-1", "name": "Rho guanine nucleotide exchange factor 6", "aln": "----------------------------------------MNPEEQIVTWLIS-----LGVLESPKKTICDPE-----------EFLKSSLKNGVVLCKLINRLMPGSVEKFCLDPQTEADCINNINDFLKGCATLQVEIFDPDD------LYSGVNFSKVLSTLLAVN----------KATEDQLSERPCGRSSSLSAANTSQTNPQGAVSSTVSGLQRQSKTVEMTENGS---------HQLIVKARFNFKQTNEDELSVCK--------------GDIIYVTRVEEGG--------------------------WWEGTLNGR----TGWFPSNYVREIKSSERPLSPKAVKGFETAPLTKNYYTVVLQNILDTEKEYAKELQSLLVTYLRPLQSNNNLSTVEVTSLLGNFEEVCTFQQTLCQALEECSKFPENQHKVGGCLLSLMPHFK------------------------------SMYLAYCANHPSAVNVLTQHSDELEQFMENQGASSP-----------GILILTTNLSKPFMRLEKYVTLLQELERHMEDTHPDH----------QDILKAIVAFKTLMGQCQDLRKR---------------------------KQLELQILSEPIQAWEGEDIKNLG------------NVIFMSQVMVQYGACE--------------------------EKEERYLMLFSNVLIMLSASPRMSGFIYQGKIPIAGTVVTR-LDEIEGNDCTFEITGNTVERIVVHCNNNQDFQEWLEQLNRLIRG-------------PASCSSLSKTSSS--------------------SCSAHSS-FSSTGQPRGPLEPPQ------IIKPWSLSCLRPAPPLRPSAALGYKERMSYILKESSKSPKT-------------------------------------------------MKKFLH-----------------------------------------------------KRKTERKPSEEEYVIRKSTAALEEDAQILK--------------------VIEAYCTSANFQQGHG-------------------------------------------SSTRKDSIPQVLLPEEEKLIIEETRSN-----------------------------------------------------------------GQTIMEEKSLVDTVYALKDEVRELKQENKRMKQCLEEELKSRRDLEKLVRRLLKQTDECIRGESSSKTSILP-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T5Z9-1", "uniprot_id": "A0AB32T5Z9_DANRE", "id": "A0AB32T5Z9-1", "name": "", "aln": "----------------------------------------MNPEEQTVTWLIT-----LGVLNSPKKNIADPE-----------EFLKTSLRDGVVLCKLIERVLPGAITKYSAEPKCEADCIANIREFLKGCQSLKVEGFDAES------LYSGENFNRVLSTLSAIN----------IATQDCSRSCPQSNTSTSSLSTPSQAAP---TLKSSRSLRRQSKAVEMSENGGG--------GQLVVKARFNFKQNNEDELSFSK--------------GELIHVTRQEEGG--------------------------WWEGTLNSK----TGWFPSNYVREVKPCDKPISPKAIKGFDVPQLTKNYYSVVVQDILEHEREFVKELQNVLGGYLRPLQASDKLSSVDCSSLNGNLEDILSFQQGLCLTLEECSKVPEGQQRIGGCYLNMMCQIR------------------------------TLYLSYCSSHPSAVCVLTDHSEELDKFMESQGASAP-----------GILTLTTSLSKPFMRLDKYPTLLQELERHVEEAHPDY----------SDILKATAAFKNLVTQCQDLRKR---------------------------KNLELQILSEPVRGWEGDSMKSLG------------QVIYMSQIHMQSSANE--------------------------EKEERYFMLFPNVIIMLSASPRMSGFIYQGRLPLTGTSVTKQPEDAETGHYAFEITGGSIDRTMVFCSSLQEQQDWLEHLHPYIKVGSPFETVLKVIAFFAAFTSIQLNSKSNVMFLCILQSVDVKPLTMPGTSSHHLHGFGTTAVNRGPLEPPK------ITKPWSLSCLRPAPPLKPSAALGYKE-------DSSKSPRP-------------------------------------------------IKKFLP-----------------------------------------------------KRKTERKPSDDEFLLRKSTAALEEDAQILK--------------------VIEAYCTGASLHQSTTG----------------------------------------FMFSVRKECVPQVLLPEEEKIIVEDIKSN-----------------------------------------------------------------GQTTIEEKSLVDAVYALKDEVHELKKENKWMKQCLEEEQKSRKELERVVRKLAKQKNDCSWDEGGH-------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8DZ19-1", "uniprot_id": "A8DZ19_DROME", "id": "A8DZ19-1", "name": "", "aln": "MDQPLVVQAEYSFMGSNNDELCFQKGDVITVTQREDGGWWEGTLNDKTGWFPSNYVNECKVQLPLTETIRPPEEIQEYRSVVLKDLLDSERAHVAELQGLLENFLEPMQQTQILSQDEYAQLMCNFVEIVRTHEDLLIQIEECNDRVGKLFLTSAPLMKKVHQAYCAAHPKAIVILDKYKDELEKYMERQGAATPGLLVLTTGLSKPFRRLDKYSAMLQELERHMESSHPDRGDTQRSVAVYKDIAATCSATRRQKELELQVLTGPVRGWQGQELSTLGDIIHMGSVAVGADHRDRYFVLFPQTLLFLSVSQRMSAFIYEGKLPLTGIIVNRLEDTDALKNAFEISSPLIDRIVAVCQGPNEANKWVELLNANNPSLPMGIKRQLSNLSNSSLGHLNAAHLSQHLDSRGYCTRFSLCAYYSSPPCHVRPLRVTLPPSNYPATAPYANLSAHFARLVKGGGLRSAIVKMLLYPQARQSIDLKRIALRKRRCHKASAKLKDLNTNQDSGQSELERQDAIELPTDSESYDDDFEDDFLHSCDSDPFEYVQFYQNKRNDSMCNSTGTFVDHGTGARRHCSSINLIKLDSADTDEVLALNELKKESLVIGSRALRALARKSTTRNSSVHTSTATLELGVGGSITNCVEEEPILKVKPSFSLQQQSSDASSIFAARLGGAFTACENLASMPDDLSRESSIQEPPTPLPASPTERHSMPTIFVGNRFNHSKNTEVYVPTWRDRQEMQNQSVDAKQDEELHSSSIDLPAACLSAPDKLQAELLYNYDEILEKPLQLHRELTPFPGHNLNSDKRVSHKSDSPSTGN---------AKTDPNLATRSSSTTELCIDTTSKKRTTPSERSRDSIRRCISYQFLQMSNRPPPPPPPRRDPDLHLDTKCRCCENSQCPSPRSSDSGMAGSCTITSPDPPNPESYFPMEAAGHDMLDNVEPERFDVCGMFREKFLTPEATQDVVDLSEEQPQLSDEPTTPTNRKEEPTCITSAQVQVNTRSIFLPSSSSMDETNRNVPANNILFSSSSADQLEPQATFRSGMYAHWWKKERLPPEVVRGIAHAYNKSLPSKDSKDSGSVCSSCFCSLGASGYSEGALYCSVCQNCADYYNGSVTSTTNTTTTTSSASCPLCSEDEGMIAPTHDSSSLDCPICNGRIASGAEEGKQSEMDRRPDVAAIKPHTPTARRPSASHSQQHPGRQQQRREPQPPGVSGHQLDVASQTEPVVQPPSQLQSVHAHSASTTSSASTTTTKSAKSSGGIRPQIKFSPDTKQQDSSSTPGVIHGRQSSNSGSGSSSGGSGGNGGAKRKERKHKG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : . *: : * . .:.: ** ::*.:. . . * *:...: . . . *: : *: :::: * :: : :. * *. :.:* .: * : : . . :. ... : * . : .: * :. . : :. : :: :* **.. . *::*:: *. :**.* . :: ::: . *: : : : . :::: :: : . ::*..: * *:: . . :: .:. :.. * . . * .: . .: :: :: * . .: : *. :.:. : :* *.* * : *.** :: * . :: : :. *: :::* * . : ::*:*. *** : .. . * : : .: . *: ::: * * :.. :* . : * ...: ::.: : . * :: . :. : .. : :: :*: : .: * . .: . :.: . :: * * .: * : . **.** * . : :.*:.* . :*** :*:*: . :: :: .*:* * :: : .** .. ::. . ... . * .*:* :* *. . :: * .:.* .:::.:: .. ... . .. . . :* * . : :.. ", "identical_positions": 87, "similar_positions": 283, "identity": "6.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101014-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y6G3-1", "uniprot_id": "RM42_HUMAN", "id": "Q9Y6G3-1", "name": "Large ribosomal subunit protein mL42", "aln": "MAVAAVKWVMSKRTIL---KHLFPVQNGALYCVCHKSTYSPLPDDYNCNVELALTSDGRTIVCYHPSVDIPYEHTKPIPRPDPVHNNEETHDQVLKTRLEEKVEHLEEGPMIEQLSKMFFTTKHRWYPHGRYHRCRKNLNPPKDR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q839-1", "uniprot_id": "F1Q839_DANRE", "id": "F1Q839-1", "name": "Large ribosomal subunit protein mL42", "aln": "MASGHISRLANLFTSVNPSKHLKPFR-GLFLSSVSKSTVGGSSIHDDSNVEIAVTSDGNTIVCFHPADDVPYELTQPIVRPDAISGHAETHEQVLKDRLGKAVLADKKAPTIEELSKMFYTTKHRWYPVGQFHNRRRKLNPPKDR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . :. : . * : *** *.: * : . *** . . . :.***:*:****.****:**: *:*** *:** ***.: .: ***:**** ** : * ::.* **:*****:******** *::*. *::*******", "identical_positions": 71, "similar_positions": 38, "identity": "48.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101019-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NG48-1", "uniprot_id": "LINES_HUMAN", "id": "Q8NG48-1", "name": "Protein Lines homolog 1", "aln": "--------MKVFCEVLEELYKKVLLGATLENDSHDYIFYLNPAVSDQDCSTATSLEWANTC----GIQGRHQPISVGVAPIAVAPVCLKTNSQMSGSREVMLLQLTVIKVMTTRILSVKTEFHAKEQYRDVIKILLESAKVDSKLICMFQNSDKLLSHMAAQCLALLLYFQLREKIT-----LSNSWIAFCQKNLSEYSESNKAIYCLWTLTAIIKEIFKDSCSQKTEILKQFLTHFDTIFEVFYNSLFSQHFENCRDTSK--IVNILMCFLDLLELLIASRIHLKLHFTCQRILFLKPSCMLEVITWPIQAFVKRKVIIFLKKCLLCKVGEDLCRGSVPALMPPDHHVAVDMLALANAVLQAVNSGLLKTLSVYEKHSFFGGDEVQPECELITSPDHVILRAASLVIMKSLEIKFQNYSS-ASEVKVDLQRFMSELLTFLKPHLQPSLQLHNPCKWLSRVFIEQDDDMLEAAKASLGIYLTLTRGCEATESLTQGKEMWDHHTHENGYNPHCIFLFFLKNIGFDSTVLLDFLISSETCFLEYFVRYLKLLQKDWDNFFTICNNFDATESKYDISICGCVPSLVQDQSSNQTIPHRLTAPHSHRDVCARHSWASDAPSEPLKAVMSKGAHTMCASSLSSPRASQSLVDYDSSDDSDVESTEQCLANSKQTSLHQQATKEIQDAAGTSRDKKEFSLEPPSRPLVLKEFDTAFSFDCEVAPNDVVSEVGIFYRIVKCFQELQDAICRLQKKNLFPYNPTALLKLLKYIEVISNKTMNTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3U1D0-1", "uniprot_id": "LINES_MOUSE", "id": "Q3U1D0-1", "name": "Protein Lines homolog 1", "aln": "MRYILDIKMEIVQEILDQLYRKVLLGTTLEDDVHGYIFYLNPDLSEQDGCPAFPVAQSNASGVLDGMAGQHGPSSHEVATLPGAQECPKRQLQMDRTREMKLLQLTVIDTMLSQVLSDETETHAKEGYRELTEVLLQSVELDSKLMRMLQNSDKLLSHMAAKCLASLLYFQLREKVRSQHKMLSNSWVTFCQKHLSESSESGEAVRCLWILTAVIKEILKDTHSQRAESLKQLLTPFDITFEVFYNSLFSQHFGDFQSPSN--LASSLMCFLELLELLVASRIHLKLHFRSQRMLFLKP-HALDILAWPIPAFIKRKLVILVKKCLLCKVGEDLCREPAPSLMSPDHLLDSDMLTLADTLLHAVHVGLWKALAVSGKPSCFGGDEVQPGCRLRTGPDHVTLRAASLITVKSLEIKSQNCTS-AAEMKVALQTFMSELLAFLKPHLQPSLQPHNPCEWLSRVFIEQDDDMLEAAKASLSIYLQLTREWDASASLTQEKEAWIRSTHGHGCNPHCVFLFFLKNVAFDSTVLLDFLISSETCFLEYFVKYLKLLQKDWAHFLSICKFFAAVESQCGMLVHDPVPSPARGRSTSLTVPHAPASPVG-ENTCPWLPWASDASSESQSQVMMPKETLPVPANGPPSRTPQSLVDYDSSEASEEETTSEHLANSKQTSLCQERSEEIQGLPRTWEEQKEHSLEP----LLSAESSSPFSAKGRVAADGTVWQVGLFLRTVKCLEELQGAIYRLQEKNLFPYNPAALLKLLKGVEAKCVNV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58G352-1", "uniprot_id": "A0AC58G352_DANRE", "id": "A0AC58G352-1", "name": "", "aln": "------------------MNISETESIKNFDWKFAIKLYVIMEVSELDFHSVFGLLHAGSA-----------PGLSSEDLASRISSCVQTVTNTDDT----CLSLSLIESVISRLAAHSFTADAAVYYQDVIRRLFTERNLMAKLVSLLSCQDKLVSHFSAKCMSVYVIKELGIAGLS-----SCMWTDACAAVLERSVSGCELDSCLWSVTAVIKGVLKADMGQNKRVLTRLLSALDSSITHLYRNLLPLSTKDPHSTDMKCVCKSMSEFIELLEALNAARLRHGLSSSAQRLSFTLCSSLLHVIRTDVEYVVKKRVLLLLKKSVLRRAGDDWALGDVRSASGEDLSLTEDLLSMADTVLQEVNAGWLKEVPVKAQASFFGGN---CDVDGTMKKDDVILRAVSLILLKSLEIKMKSLGQQGSAGEIEAQQYLTELMLFLQRHVS---LDSHRCCWVSALFAEQDDDMMEATNTLMALYLYQKRSCSDSG------------VCVWGFNPHCLFILLLRSLSFDHSVLLDFLISSETCFLEYFVRYLKLLWQDWTGLCRSSQHIEDGGGDAKR--------------------------------------GSDLSIPASSAAAAVPCGESATGNQVETALVSRLVDYGSSDESEEADAVDCGAS------------------------------------------------------VMLVEESLLGKVLACLMDLRTAVSRLYNRGLFPYNPSSLLKLLNGVESQRNRLR---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . . : . :*: :*: * .. : :.:. * . * : : . : *.*::*. : ::: : . .* *::: . *: . :: :**: ::. .***:**::*:*:: : :* * * * *.. .. : *** :**:** ::* .*. . *.::*: :* : :*..*:. : :... : . : *::*** * *:*:: * .**: * *.:: : .:*:::::::**.:* :.*:* . . : * : *:*::*:::*: *: * * :.* : * ***: *.* ***.**: :****** :. . .: :: * :::**: **: *:. : * *:* :* ******:**::: :.:** .* . : . * ****:*:::*:.:.** :******************:***** :** : .: : .. .** . . . . ... . . ****.**: *: : : *. : : .:: : : *: :*: *: ** ::.******::*****: :* . ", "identical_positions": 165, "similar_positions": 211, "identity": "21.24%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101020-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61647-1", "uniprot_id": "SIA8F_HUMAN", "id": "P61647-1", "name": "Alpha-2,8-sialyltransferase 8F", "aln": "MRPGGALLALLASLLLLLLLRLLWCPADAPGRARILVEESREATHGTPAALRTLRSPATAVPRATNSTYLNEKSLQLTEKCKNLQYGIESFSNKTKGYSENDYLQIITDIQSCPWKRQAEEYANFRAKLASCCDAVQNFVVSQNNTPVGTNMSYEVESKKEIPIKKNIFHMFPVSQPFVDYPYNQCAVVGNGGILNKSLCGTEIDKSDFVFRCNLPPTTGDVSKDVGSKTNLVTINPSIITLKYGNLKEKKALFLEDIATYGDAFFLLPAFSFRANTGTSFKVYYTLEESKARQKVLFFHPKYLKDLALFWRTKGVTAYRLSTGLMITSVAVELCKNVKLYGFWPFSKTVEDIPVSHHYYDNKLPKHGFHQMPKEYSQILQLHMKGILKLQFSKCEVA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K4T1-1", "uniprot_id": "SIA8F_MOUSE", "id": "Q8K4T1-1", "name": "Alpha-2,8-sialyltransferase 8F", "aln": "MRSGGTLFALIGSLMLLLLLRMLWCPADAPARSRLLMEGSREDTSGTSAALKTLWSPTTPVPRTRNSTYLDEKTTQITEKCKDLQYSLNSLSNKTRRYSEDDYLQTITNIQRCPWNRQAEEYDNFRAKLASCCDAIQDFVVSQNNTPVGTNMSYEVESKKHIPIRENIFHMFPVSQPFVDYPYNQCAVVGNGGILNKSLCGAEIDKSDFVFRCNLPPITGSASKDVGSKTNLVTVNPSIITLKYQNLKEKKAQFLEDISTYGDAFLLLPAFSYRANTGISFKVYQTLKESKMRQKVLFFHPRYLRHLALFWRTKGVTAYRLSTGLMIASVAVELCENVKLYGFWPFSKTIEDTPLSHHYYDNMLPKHGFHQMPKEYSQMLQLHMRGILKLQFSKCETA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58IMW5-1", "uniprot_id": "A0AC58IMW5_DANRE", "id": "A0AC58IMW5-1", "name": "", "aln": "MRCG-----ATDRCVTFVPFSYTHTHTHTDGAGAVGLQAAGGPDCLSECVCDVLLHTGHTLTRRCSDGFAP-----AAALCKTQTPVLRPHPRQECSLNMKKFSQELSDFLNCPYKQNTSEQQFNRMRLQYCCNATHSLILTKRNTAVDHIITYETEGKRTYRVKADLHKMLPEDSPWSAGALGLCAVVGSSGILKNSSCGRQIDSADFVIRFNLALVN---DSDVGLKTDLMNINPSQILTQYKTMEQDPGPLVERISVYGNSSLIIPAFAYGFCTSPSLRVLRVLQPIRPQQPVVFFNPHYLRALDRFWKWRGLKEPRLSSGFILISAALEMCEHVHVYGFWPFGTDLQENPVPYHYYDQSKPSPYMHRMPEEFVRLLQLHSQGALTLHLQPCHTP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * : :: : :.: . . : :: : : .. .* . .:.* .. : : ** :.. ..: . ..: * :::: **:::::.* * :* **:* :.:::::.**.*. ::**.*.*: :: ::.:*:* ..*: . . *****..***::* ** :**.:***:* **. . ..*** **:*:.:*** * :* .:::. . ::* *:.**:: :::***:: *. *::* .*: : :* *:**:*:**: * **: :*:. ***:*::: *.*:*:*::*::******.. ::: *:.:****: *. :*:**:*: ::**** :* *.*::. *...", "identical_positions": 111, "similar_positions": 158, "identity": "27.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101021-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5SUS0-1", "uniprot_id": "FBW10_MOUSE", "id": "Q5SUS0-1", "name": "F-box/WD repeat-containing protein 10", "aln": "----MENREPKLKQAPYFRCEKGPNWVPVCQKCEACVLAWKIFATKEWFRRVNDISQRRFLVSILGQLNSLYLLQYFQNILETTQGKDFIYNRSRIKLSRKGGKEEEVVKSSLNQMLDKTVERKMKEILYWFGNSTHRTKANYTLLLLQMCDSNLLLTAANVIRVLFMKEWNSISGLHDDTPDVMFFPEKKYSGTQDTSYVSWAARPKPVSFPMSKHLGNKLGTENVDRETTEGKGESSLQCIHEMNRQIFGKGGMSRLGDDPCNLLLSLDHVQLLSSGYSKYRDFIRDLPLHLSKYILRMLDKHSLNRCIFVSQHWATLAQQVKVDQSMHSFIQNQISLLQVTKEEKQAYTGSYTRGIDPNYANKVSIPVPKIVDDGKRSRSKNQKWKLRTKTDYNLWNAYQNQETQLVQMEERNVFCGTYNIRVLSDTFDQNRIIHYNGGDLMAISS-NRKIHLLDIMQTKELPIEFRGHAGSVRALFLSEEDNILLSGSYDLSIRYWDVKTGACVRIFYGHQGTITCLDVYKNRLVSGAKDGQVKEWDIETGKCLK--TFKHKDPILAAKISETYIVSSCERGIVKVWHVVTAQLQKTLTGHEGAVKCLFFNEWHLVSGGADGLVMAWSMVGKYERCLMAFKHPKEVLQVSLLYLRVISACGDGKIRIYNFLNGNCLKVIKVDARGDPVLSFFYQGNRMVAHTDSNILVFQFENVKWQYSSDKNKVKKSKDKEEEREETSLGDEHSRSTIQGHSLKDSVSSKQ---------EFSKSRVHLKQTKN--------LSSD--------------------DMETPVGEVSHPLQKLWKVPMTPDRFLLTISALQQAHNSEEFAYPHRPRPQVIDAWGPSIPYPRKVLSLKGKSVQHAVDQLRSSNLPTGVRQTNIPLEIQKLQPNLKKSLHSP------RVQATVPQPSLIRPKVSDSLRGDEHLTSSIDGTMRRAGPLTSMQVIKPNRMLAPRGGTATLSPKKERPRFYTTLDPLRMNTGFMLMTVKEEKEFAEAKMKEYEASVSTKEVDPGKASKAAWIRKIKGLP--IDNFMKEGKTAAPELGQNVFI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5XX13-1", "uniprot_id": "FBW10_HUMAN", "id": "Q5XX13-1", "name": "F-box/WD repeat-containing protein 10", "aln": "----MENLESRLKNAPYFRCEKGTDSIPLCRKCETCVLAWKIFSTKEWFCRINDISQRRFLVGILKQLNSLYLLHYFQNILQTTQGKDFIYNRSRINLSKKEGK---VVKSSLNQMLDKTVEQKMKEILYWFANSTQWTKANYTLLLLQMCNPKLLLTAANVIRVLFLREENNISGLNQDITDVCFSPEKDHSSKSATSQVYWTAKTQHTSLPLSKAPENEHLLG--AASNPEEPWRNSLRCISEMNRLFSGKGDITKPGYDPCNLLVDLDDIRDLSSGFSKYRDFIRYLPIHLSKYILRMLDRHTLNKCASVSQHWAAMAQQVKMDLSAHGFIQNQITFLQ----------GSYTRGIDPNYANKVSIPVPKMVDDGKSMRVKHPKWKLRTKNEYNLWTAYQNEETQQVLIEERNVFCGTYNVRILSDTWDQNRVIHYSGGDLIAVSS-NRKIHLLDIIQVKAIPVEFRGHAGSVRALFLCEEENFLLSGSYDLSIRYWDLKSGVCTRIFGGHQGTITCMDLCKNRLVSGGRDCQVKVWDVDTGKCLK--TFRHKDPILATRINDTYIVSSCERGLVKVWHIAMAQLVKTLSGHEGAVKCLFFDQWHLLSGSTDGLVMAWSMVGKYERCLMAFKHPKEVLDVSLLFLRVISACADGKIRIYNFLNGNCMKVLKANGRGDPVLSFFIQGNRMVVNTESNVLMFQFEHIKWQYAVEKTKQKKNKEKEEEKEENSLMEILSKCNIQVHSPRESVSSKQTVIQELLPGKPPKSRVLLKPAKFSSAVLIEELQSQGKSKSPRRDADDVEKAQKQGQLETPGKLPSHPKKKSWKIPMSPDQFLLTVSALQHAHNSGEFAYPCRPQTEITDVWGPSISYPRKVLNFKGKSIQRAVDRLRLSNPPIDVKRTSIPLEIQKLQPNLKISLHSP------RVQSTIPQPMIIRSRFSGSLKGGDQVTSSIERAVCSTGPLTSMQVIKPNRMLAPQVGTATLSLKKERPRIYTALDPFRVNTEFVLLTVKEEKEHQEAKMKEYQARESTGVVDPGKVSKAAWIRKIKGLP--IDNFTKQGKTAAPELGQNVFI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U1E3-1", "uniprot_id": "A0AB32U1E3_DANRE", "id": "A0AB32U1E3-1", "name": "", "aln": "MTGVKCLRGEAGDSVLEWSCRGEDGDFNICGRCQTCILSEQLHHIAEWINKAGWDSRKRFITGILVRCQSLQILESLQSVLQVTSGKDYTYARSRALPEDTMWS------MDGGGPDGKIHGLDVLETWEWFRKSPDWTKSKYVLGLLTLCDTHLLHMLGNLVRVLIIWEKHRFLQFSNSVKDSKSLKSICNQVELDSDSCDGPDPALTVVPRSSKS-----------------------------------------------------------LSGVSCHIDFIRRLPVNIAKMTLGQLDKVSLSSCRRVSKHWQSLTEEILTEMEVKKRVKKQAMIFQ----------GNSTSKVNPVYAKICEVLVP-ISEGDKHFQHGGTSPRHTQSQGQVLDSLYKGFKTEKIQLEERNVYCGVYNTSVLLEREDGSRVMHYAGGQLVAVGSRDRTIRLLHIGSLKELPLVIQGHSGSVRAVLVCEEKDLVISASYDLSIRCWNLKTGMCMMIFHGHFGTINCLDLVGDRLVSGAKDCRVKVWNLQTGKCVENLKFKHPKPIMCVKMSETLVISSCSGGQIRIWSIQTALLIRQISGHQGAVLCLCFDQWHILSGGSDGVVKAWSTNSSFKKCLRTFQHPKEVLAMSFLFLRIITGCMDGKIRIFNFLNGDCLRVIKTNMKQCPVLSLHMHHNTVVVNTRGSVLMLQFAEVQWDYSARAVRDLTEQFHVSPKNVPRSTERATQGGSSGLKSHPHHSKNLS------TTNMQHAQVAQRESTR-------------------------------AAMWSKLQAYSHSRTSINLQSEFITRPRSVLSAGKPVSGYKGFQNRVSHTPSTATSSSDKKTKNDIKHSVLSRSEKAVRERVRKRGPHHPVTPERILLRAGSSQQGHNSDPARSNMELNARVRDAWGPDACRQPSFQTSTKKPSETNTPFTMHSVDLNPQSSLQAHSTS-----KQSQRSLKVNKIDPLNVTCLEDDKTPQGLLVRQTSMPKHCHEDLEMTSKSSLRHIQLDPYKRSEVFQLRTDTQMEAFLQECTRQQQVCKNGSGDKR--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... : *. . . :* :*::*:*: ::. **: : . *::**:..** : :** :*. :*.:*:.*.***: * *** . . . . . .* .: * ** :*.. **::*.* ** :*:.:** .*::***:: * : : : :. * . . :. . . . ** ** * : **** **::::* * **: :*. * **:** :::::: : . : :::* ::* *. * ::* **: .: ** : :..* : . : . * . *:. :*: : :*****:**.** :* : * .*::** **:*:*:.* :*.*:**.* . * :*: ::**:*****:::.**.::::*.******* *::*:* * ** ** ***.*:*: :*****.:* :** *:::****:: .*:* .**:..::.:* ::***. * :::* : * * : ::**:*** ** *::**::**.:**:* *** ..:::** :*:****** :*:*:**:*:.* ******:*****:*::*:*.: : ****:. : * :*.:* ..:*::** .::*:*: : ..: : . :: : :: . . : *.: : :::* : :. : : **. . . : .:** : . . * .. . . . .. .:* : . :::* . * * *. . * . : . . **: : :. .. * : .. .:.: .* :*:*. ... : . :*. :* * * *: : ::: .. *. * :: :** * *:. :*. . : ::: :: :.. *:: ", "identical_positions": 251, "similar_positions": 332, "identity": "23.2%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101021-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NWA0-1", "uniprot_id": "MED9_HUMAN", "id": "Q9NWA0-1", "name": "Mediator of RNA polymerase II transcription subunit 9", "aln": "MASAGVAAGRQAEDVLPPTSDQPLPDTKPLPPPQPPPVPAPQPQQSPAPRPQSPARAREEENYSFLPLVHNIIKCMDKDSPEVHQDLNALKSKFQEMRKLISTMPGIHLSPEQQQQQLQSLREQVRTKNELLQKYKSLCMFEIPKE-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VCS6-1", "uniprot_id": "MED9_MOUSE", "id": "Q8VCS6-1", "name": "Mediator of RNA polymerase II transcription subunit 9", "aln": "MASSGVAGGRQAEDTLQPPPE-LLPESKPPPPPQPLPVAALPP--PAAPRPQSPAGAKEE-NYSFLPLVHNVIKCMDKDSPDLHQDLNALKTKFQELRKLIGTMPGIHVSPEQQQQQLHSLREQVRTKNELLQKYKSLCMFEIPKD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "R4GDN4-1", "uniprot_id": "R4GDN4_DANRE", "id": "R4GDN4-1", "name": "Mediator of RNA polymerase II transcription subunit 9", "aln": "MAAA-VPVVEEAED------------------------------------------------YSFLPIIHDVIKCMDKDSPDVHQELNKLKTKIQEAREQISSMPGIDMSPAVQESKLQTLREQVQTKNQLLQKYKSLCMFDIPKPS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:: *. .:*** *****::*::*********::**:** **:*:** *: *.:****.:** *:.:*::*****:***:***********:*** ", "identical_positions": 62, "similar_positions": 27, "identity": "42.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101021-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y584-1", "uniprot_id": "TIM22_HUMAN", "id": "Q9Y584-1", "name": "Mitochondrial import inner membrane translocase subunit Tim22", "aln": "MAAAAPNAGGSAPETAG------SAE-APLQYSLLLQYLVGDKRQPRLLEPGSLGGIPSPAKSEEQKMIEKAMESCAFKAALACVGGFVLGGAFGVFTAGIDTNVGFDPKDPYRTPTAKEVLKDMGQRGMSYAKNFAIVGAMFSCTECLIESYRGTSDWKNSVISGCITGGAIGFRAGLKAGAIGCGGFAAFSAAIDYYLR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CQ85-1", "uniprot_id": "TIM22_MOUSE", "id": "Q9CQ85-1", "name": "Mitochondrial import inner membrane translocase subunit Tim22", "aln": "MAATAPKAGGSAPEAAG------SAE-APLQYSLLLQYLVGDKRQPRLLEPGSLGGIPSPAKSEEQKMIERAMESCAFKAVLACVGGFVLGGAFGIFTAGIDTNVGFDPKDPYRTPTAKEVLKDMGQRGMSYAKNFAIVGAMFSCTECLVESYRGKSDWKNSVISGCITGGAIGFRAGVKAGAIGCGGFAAFSAAIDYYLR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FA60-1", "uniprot_id": "E7FA60_DANRE", "id": "E7FA60-1", "name": "Mitochondrial import inner membrane translocase subunit TIM22", "aln": "MAAPAKSTDASLSVTAGHSANVSSAENVSLQYSLILDHLIGDKRQIKDLNPTVMGALPSPQKTDEQKMIERGMESCAFKSLIACVGGFVLGGAFGVFTAGIDANVGLDPKDPLRTPTAREVLKDMGQRGMSYAKNFAIVGAMFSCTECLIESHRGKSDWKNAVYSGCITGGAIGFRAGLKAGVLGCGGFAAFSAAIEYYLR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.* .:..* . :** *** ..*****:*::*:***** : *:* :*.:*** *::******:.*******: :*************:******:***:***** *****:******************************:**:**.*****:* **************:***.:************:****", "identical_positions": 147, "similar_positions": 36, "identity": "73.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101021-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VSB2-1", "uniprot_id": "Q9VSB2_DROME", "id": "Q9VSB2-1", "name": "LON peptidase N-terminal domain and RING finger protein 3", "aln": "MPLSQGYCQQEQQDQGHHMPPSSPIQCYLPHNDSQNSLHYLLAESFAKVGSLPEAFDVYELIASRQFDGHVPLDKLNTLASALTTHIRQMGGIATPTPTPTPTPMSAVHVKSPRISERLDMMPWSRYHHQGKQNQAEQGEFLRGVGESMDEAGDSPLDMHSPTRELRVPSPLQDLEDFDPLMCPLCSDILRCPVTTNCGHTFCRQCCETITQCNICQVRFPRIQASSPGPPVCALTTTTASGAGSSLFTAPSNHNANLSLISFPVGYGVQLSSSVQRLAAPPMTVTTTTVASTTATATTTMASTSAAAALGLSAYPSAHGGGIGSTAMKFMPDVLVRRLVEKWWGPDLQAKKISEKASSCMHLNLLDDALKFCNASLEKSPANFKSLCLRAEVLLKLSHYQSSLADIENALRTRCTSPKAHYLRALALSGLGRLEEALYNGFLAICLDKKTNLSNSEIFQHDLAKILQRLLAHMPKNRTSLSSATVPVFQQQHRNFATSRAPYPLLWEQVRRRRKQQHHHHHHHHHHHVHLDDVEDEFGHYNNYIMAGDDMEEEVEVEVEGGEPGSLHLDGDFLFPSALDFMDHHRHQRHVFEQKQFDLQPRRHANRKHCKRKWSVAMESMGGKDLEEEDVDRAHAAGESQRCSRLFAGVLDRTQQELQRLKKLDKSAPSLAVSSVAGQLIDASDFDCVVCSRTLWKPVVTPCGHTYCLVCLDRCMDYNSPCPLCMSPLVEFNVNASASTSASQHPNPNQNQIHLHPGSSSPVPFALAKRPVTKFLEAAMKRFIPDHYEARFRQEIDQEPSVPVFICTAAFPAVPCPLFVCEPRYRLMVRRAVESGDKTFGIVQPNGGKSRYYDVGTILDIRDCVQLGDGCSILSTIGCKRFKILARNEKDGYETAKVEYICDEPIADEQVKILAGMQGVVLAKASEWFESLSTEQKHEILQSFGQMPPLEPNWELISDGPAWAWWIIALLPLSQQLKVDILATTSLEKRLRAIDKTLDWLHDLSHPQQPAHHPMNHHQQAPQSPQQAHHLDLDCEEQEGASSGSDECCLFAETGNEPHTDEELLL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M9QPJ1-1", "uniprot_id": "A0A8M9QPJ1_DANRE", "id": "A0A8M9QPJ1-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKEWVMDLLECPICLFLMCEPMTMSCGHSFCRRCMG----------------------------------------------------------------------------------------------------AFLPSRCPTCKERLKQRDAKNIKNNVLLFSIIEKCCP---EETKMKCHIQEKLKTSEFTEALRIADEGIEMAPDDVSLKVWRAEACMGLRRFSDALRDLDDLCFVRPNWTEGFFRKGNVLLEMGRQTEALIQ--FYRCLKQHPDFAP---AKNQIKKILEAEGMAVPEEVPRILHVVSEFLQDPCPITSSVSP---------SCTDAQRYSHTNAEGQSDSGQNTTKMKLGSSSECCLS---------------------------LCQAVSFLPTAEDDEELMMKR----------EEKHNRGVCSVGRESCLS--------------------------------------------------------VLTVSDFECPLCIRLFYEPVTTPCGHTFCKNCIERSLDHNLRCPLCKQPLQEYFKNRKYNP-----------TVLLQEIMSRLFPQQLAER--------------KQVHEAEMAELSNLTKDIPIFVCTVAYPGIPCPLHIFEPRYRLMMRRCMETGTKKFGMCSYEHGKG-FADYGCMLDILDLDLLPDGRSYVETLGGSRFRVLRRGQRDGYHTADIEYLEDHKVEGAELEILQRLHDSVYQQAREWYLRLNSRIQDQISRQYGIMPEKEDNIQASANGPAWCWWLLSVLQLDPSYQTTVLSLTSLKDRLGHLRIVLEYFSQS--------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* * **:* :: *:* .***:***:* *: * *:.: * :: :**: ::** : .*:. : .. :: . : :**::.: .:* :* :.. ***. : * ::..:* *::: .* . .:..: :. .* :** *** : : **.::.::: :::: ***: :*:: . : .. .:*: :: . *:: * : . : . : .: ::* .: :: : .*:.*: ..:..:: :: :.** : **. ** . :: .***:* :* * :::**.******:* *::*.:*:* **** .** *: * . .. : *: * .* **:* : :**.: : : .:*:*:**.*:*.:****.: *******:**.:*:* *.**: . : **. : * * :*** * * ** * :.*:* .**::* *.::***.**.:**: *. : . :::** ::. * :* **: *.:. :.:* :.:* ** * * : ::****.**::::* *. . :. :*: ***:.** : .*::: : ", "identical_positions": 171, "similar_positions": 229, "identity": "16.04%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101025-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UQF2-1", "uniprot_id": "JIP1_HUMAN", "id": "Q9UQF2-1", "name": "C-Jun-amino-terminal kinase-interacting protein 1", "aln": "MAERESGGLGGGAASPPAASPFLGLHIASPPNFRLTHDISLEEFEDEDLS---EITDECGISLQCKDTLS---LRPPRAGLLSAGGGG-AGSRLQAEMLQMDLIDATGDTPGAEDDEE---DDDEERAARRPGAGPPKAESGQEPASRGQGQSQGQSQGPGSGDTYRPKRPTTLNLFPQVPRSQDTLNNNSLGKKHSWQDRVSRSSSPLKTGEQTPPHEHICLSDELPPQS-------GPAPTTDRGTSTDSPCR-RSTATQMAPPGGPPAAPPGGRGHS---------------------------HRDRIHYQADVR-----------------LEATEEIYLTPVQRPPDAAEPTSAFLPPTESRMSVSSDPD--PAAYPSTAGRPHPSISEEEEGFDCLS---SPERAEPPGGG--WRGS------LGEPPPPPRASLSSDTSALSYDSVKYTLVVDEHAQLELVSLRPCFGDYSDESDSATVYDNCASVSSPYESAIGEEYEEAPR--PQPPACLSEDSTPDEP-DVHFSKKFLNVFMSGRSRSSSAESFGLFSCIINGEEQEQTHRAIFRFVPRHEDELELEVDDPLLVELQAEDYWYEAYNMRTGARGVFPAYYAIEVTKEPEHMAALAKNSDWVDQFRVKFLGSVQVPYHKGNDVLCAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADDSQEAKGNKCSHFFQLKNISFCGYHPKNNKYFGFITKHPADHRFACHVFVSEDSTKALAESVGRAFQQFYKQFVEYTCPTEDIYLE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WVI9-1", "uniprot_id": "JIP1_MOUSE", "id": "Q9WVI9-1", "name": "C-Jun-amino-terminal kinase-interacting protein 1", "aln": "MAERESG-LGGGAASPPAASPFLGLHIASPPNFRLTHDISLEEFEDEDLS---EITDECGISLQCKDTLS---LRPPRAGLLSAGSSGSAGSRLQAEMLQMDLIDAAGDTPGAEDDEE---EEDDELAAQRPGVGPPKAESNQDPAPR----SQGQGPGTGSGDTYRPKRPTTLNLFPQVPRSQDTLNNNSLGKKHSWQDRVSRSSSPLKTGEQTPPHEHICLSDELPPQG-------SPVPTQDRGTSTDSPCR-RSAATQMAPPSGPPATAPGGRGHS---------------------------HRDRIHYQADVR-----------------LEATEEIYLTPVQRPPDPAEPTSTFMPPTESRMSVSSDPD--PAAYSVTAGRPHPSISEEDEGFDCLS---SPERAEPPGGG--WRGS------LGEPPPPPRASLSSDTSALSYDSVKYTLVVDEHAQLELVSLRPCFGDYSDESDSATVYDNCASASSPYESAIGEEYEEAPQ--PRPPTCLSEDSTPDEP-DVHFSKKFLNVFMSGRSRSSSAESFGLFSCVINGEEHEQTHRAIFRFVPRHEDELELEVDDPLLVELQAEDYWYEAYNMRTGARGVFPAYYAIEVTKEPEHMAALAKNSDWIDQFRVKFLGSVQVPYHKGNDVLCAAMQKIATTRRLTVHFNPPSSCVLEISVRGVKIGVKADDALEAKGNKCSHFFQLKNISFCGYHPKNNKYFGFITKHPADHRFACHVFVSEDSTKALAESVGRAFQQFYKQFVEYTCPTEDIYLE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IB08-1", "uniprot_id": "A0A0R4IB08_DANRE", "id": "A0A0R4IB08-1", "name": "", "aln": "MV------LSLAMDSREEWDGWMEEQWEK----WLTHDISLDEYEDDDLSEVTEITDENGITLVHLDLDTQDHMTRPTNGAARSGRRR-EAVELQAEMLHLDLIDAEGGIQEEERDDRRPFDAIDDNHKEERGAGPPVILPQLKTLTP-----------ANDMDTYRPKRPTTLNLFPQVPRTQDTINNNSFGEKERRKEKKTHSSSPHIKGDSAAKPEQGSLTDGDKVQARADTKPRGPASTKNKASAFQNKQQDKLSESLNNPTVVAPLTQTAMRDKSTEVPLIEGVLDISTICKEKARYHTVNGYREQVQYPAENEGMCDQLVDRNKDYHISEGNATEEIHLTPVN---GEQERPFLSQSSDSNRMSISSDTELPPLHYYPSAGCPNPSISEEDEVYPPTPPCRTVSLSEQPGDSSQWAETRKPKMAKDETGNVKAVAVSTDASGLTYDSVKYTLVVDEHAKLELVSIKDCYKGYESDSD-NTVYESAIDEDDEDQEADEEDEESGARSMRRDTSCLSADSTTDTTSDVPRSRKFMNIFGNGRSRFSGAE-FGFFSCVINGEEREQSHRAVFRFVPRHDDELELEADDPLLVELQAEDLWCEAYNMRTGTRGIFPAFYAVKVAKD--ELVKEVKG-DWMDKFWVKFLGSVQVPYHKGNDVLCAAMHKIASNRRTTMQFSPPSPCIVEINTRGLKIVVQDDCRTSGRGEKCFHFFQLKNISFCGCHPKNNKYFGLITKHPANQRFACHVFFSDDTTTKLAESVGKAFQQFYKEHMEYSCPTEDIFLE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. *. . * . :: : . *******:*:**:*** ***** **:* * : : * * :* . .******::***** *. * *:. : :: .. *.*** . .. . ... *******************:***:****:*:*. ::: ::**** .*:.:. *: .*:* *. .*..* ::.:: :. : : : : *. .* : .. *.:* :*::::* *: . :*****:****: . * . .. ..***:***.: * * :** *:******:* : . : . :* **.. * : .*. .::*:*:*.*:**************:*****:: *: .*..:** ***:.. . .. :.* *: *...: : .:*** ***.* . ** *:**:*:* .**** *.** **:***:*****:**:***:*******:******.************ * ********:**:***:**::*:*: .:. .*. **:*:* **********************:***:.** *::*.***.*::**..**:** *: * ..:*:** ************ *********:******::*******.*:*:*. ******:*******:.:**:******:**", "identical_positions": 346, "similar_positions": 196, "identity": "43.85%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101025-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z0G2-1", "uniprot_id": "SRPK3_MOUSE", "id": "Q9Z0G2-1", "name": "SRSF protein kinase 3", "aln": "----------------------------------------------------------MSANAGGSG-SVDCGG--------------------------------------------SSSSSQTS-----------------------------------CGPESSGSELTPATPAPRLLQG-------------------------------LLGSDDEE------QEDPKDYCKGGYYPVKIGDLFN-GRYHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETAVDEIKLLKCVRDSDPSDPK---RETIVQLIDDFRISGVNGVH--VCMVLEVLGHQLLKWIIKSNYQGLPVPCVKSIVRQVLHGLDYLHTKCKIIHTDIKPENILLCVGDAYIRRLAAEATEWQQSGAQ---PPSRSTVSTAPQEVL---------------IGKLSKNKRKKMRRKRKQQKRLLEER--LRDLQRLEAMEAAVQAEDSS-------------------------------------------------SRLERG-------------SGSTSSSGCHPEGTRAGPSPASSS--------------------PVP-GGERSLSPS----------------------SQTSGFSGSLFSTASCSILSGSSNQRETGGLLSPSTPFGASNLLVNPLEPQNADKIKIKIADLGNACWVHKHFTEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGE-DYSRDEDHIAHIVELLGDIPPAFALSGRYSREFFNRRGELRHIPNLKHWGLYEVLMEKYEWPLEQATQFSAFLLPMMEYIPEKRASAADCLQHPWLNP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2KAH6-1", "uniprot_id": "A0A0G2KAH6_RAT", "id": "A0A0G2KAH6-1", "name": "SRSF protein kinase 3", "aln": "-----------------------MHWPRLGPTGTVVQCTRALGCDT-----------RMSASAGGSG-GMDCGG--------------------------------------------SSSSSQTS-----------------------------------CGPESSSSELAPATPAPRLLQG-------------------------------LLGSDDEE------QEDPKDYCKGGYYPVKIGDLFN-GRYHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETAVDEIKLLKCVRDSDPSDPK---RETIVQLIDDFRISGVNGVRPDVCMVLEVLGHQLLKWIIKSNYQGLPVPCVKSIVRQVLHGLDYLHTKCKIIHTDIKPENILLCVGDAYIRRLAAEATEWQQSGAQ---PPSRSTVSTAPQEVL---------------TGKLSKNKRKKMRRKRKQQKRLLEER--LRDLQRLEAMEAAVQTEDSS-------------------------------------------------SRLEQG-------------SGSTSSSGCHPEGTRAGPSPASSS--------------------PVPTGGERSLSPS----------------------SQTSGFSGSLFSTASCSVLSGSSNQRETGGLLSPSTPFGASNLLVNPLEPQNADKIKIKIADLGNACWVHKHFTEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGE-DYSRDEDHIAHIVELLGDIPPAFALSGRYSREFFNRRGELRHIHNLKHWGLYEVLMEKYEWPLEQATQFSAFLLPMMEYIPEKRASAADCLQHPWLNP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9UPE1-1", "uniprot_id": "SRPK3_HUMAN", "id": "Q9UPE1-1", "name": "SRSF protein kinase 3", "aln": "----------------------------------------------------------MSASTGGGGDSGGSGG--------------------------------------------SSSSSQAS-----------------------------------CGPESSGSELALATPVPQMLQG-------------------------------LLGSDDEE------QEDPKDYCKGGYHPVKIGDVFN-GRYHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETAVDEIKLLKCVRDSDPSDPK---RETIVQLIDDFRISGVNGVH--VCMVLEVLGHQLLKWIIKSNYQGLPVPCVKSIVRQVLHGLDYLHTKCKIIHTDIKPENILLCVGDAYIRRLAAEATEWQQAGAP---PPSRSIVSTAPQEVLQ--------------TGKLSKNKRKKMRRKRKQQKRLLEER--LRDLQRLEAMEAATQAEDSG-------------------------------------------------LRLDGG-------------SGSTSSSGCHPGGARAGPSPASSS--------------------PAP-GGGRSLSAG----------------------SQTSGFSGSLFSPASCSILSGSSNQRETGGLLSPSTPFGASNLLVNPLEPQNADKIKIKIADLGNACWVHKHFTEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGE-DYSRDEDHIAHIVELLGDIPPAFALSGRYSREFFNRRGELRHIHNLKHWGLYEVLMEKYEWPLEQATQFSAFLLPMMEYIPEKRASAADCLQHPWLNP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TFD0-1", "uniprot_id": "A0A8N7TFD0_DANRE", "id": "A0A8N7TFD0-1", "name": "non-specific serine/threonine protein kinase", "aln": "---------------MSSCSRSHFNRTSCCQYSAEPQCACSEPTEANVREVTAVPMISMNVSSSDNNLPQNSHGKKQKKKNKKHRKAAVAAAVEISSLELGPQIPSSDELCHILTIHRSATPPESSPTPPLNLSQSPPDLQPPAPIPHSIPITVVPSPVVVSSPETPSTPIAPSLGLPSILSSTPPTPQAPSNQPTPPQALSPPPPDFSPPPAELLGSDDEE------QENPSDYCKGGYYPVKIGDLFN-GRYHVVRKLGWGHFSTVWLCWDLQRKRFVALKVVKSAQHYTETALDEIKLLKCVRDSDPTDSK---RERLVQLIDDFKISGVNGVH--VCMVLEVLGHQLLKWIIKSNYMGLPLICVKSILRQVLEGLDYLHTKCKIIHTDIKPENILLEVNEVYVRRLAAEATIWQKAGAP---PPSGSSVSTAPREKQ---------------MGKMSKNKKKKLKRKAKRQQQLLDER--LIDLQRMEELDGVLPSDASGNTR--------------------------------------------ALWRLSEDEEDNVKH------AQTNGNGALNKQSPESGSSWLEES--------------------CNGYGPLRFSSPG----------------------SGLSGLSGSILSATSESALSTLSGYSTERSLLSPNS-YSAADFLVNPLESQNADKISIKIADLGNACWVHKHFTEDIQTRQYRALEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGE-DYTRDEDHIAHIIELLGAIPPHFALSGRYSREYFNRRGELRHIANLKPWGLFEVLLEKYEWPLDQAAQFSDFLLTMLEFIPEKRATAAQCLQHPWINS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A6M3Q7C8-1", "uniprot_id": "A0A6M3Q7C8_DROME", "id": "A0A6M3Q7C8-1", "name": "non-specific serine/threonine protein kinase", "aln": "---MNKADVNRRVLAIQAKKKRHKNRKRGKQNGTNPQ-EQSNSSQNQNPKPSSNPIPEPNRSSENLQAPDNANNSHLN----------------------------------------APSSAAFS---------------------------------KATATATASTSSGGSAGTPDQYQPPKKTQAKAKPNTQKEHQQQPPRSSSNESYESETFSDNED------QELMEDYCKGGYHPVNIGDLFH-DRYHVIRKLGWGHFSTVWLCWDLQAMGYVAIKIVKSAPHFAETARDEIKILKTVRETDPSNPR---RHKTVQMLDDFKITGVNGTH--ICMVFEVLGDNLLKLIRKSNYRGIPLANVKTITRQVLEGLDYLHTCCKIIHTDIKPENVLLCVDEPHVRSLATEATQLYCMNSK---MYP-SLVSRAPKEYREPP-----------ITGKMSKNRKKKLKKKAKKRMELFKQQ--RDYLEQADGQGAINPNEVQNGDAGISDADEYFDANSVEDNVHVAAGQPSRKQREERKAPPEQSEEAQEQDPLTEGTDKAKKKKKKKNKNKSNQSKGQQPPQLENSTSSAESSSALKSQQANGSNSTTNNKSNTNSSGTLKGQSNGKKMPLRPKQEKQGSNHQLNNNNSKPNSNSDSKISSGSVENTSSATNGPHSNSTLPTPPPPPQAKHKAKKDPALDECNVHVKIADLGNACWVDRHFTEDIQTRQYRSLEVIIGAGYNTSADIWSTACMVFELATGDYLFEPHSGE-SYTRDEDHLAHIIELLGPIPREILLNGTYAAKSFTRSCELRNISGLKPWGLMDVLLEKYEWSQKDAASFASFLTPMLEFDPNKRATAAECLQHPWLRXDTMQPGCWLRATQPATADGDGGALAGTGTGKGTRARATALKGGSPAVPADGEVGRGYIESSASVATLASISSIASTSAAAMAALKARPYLVAPFVTTASAPPTPHPHASISTSTARTAPATPTRRRIAPEDDLNLVEDLDVALAQIEDTQTHTKNKSQRFFWRKALRRVFQRRKXRRRRQDLPRWHRPARRCRRRNLAERVRRICACCAYGQILLRAARVALLSCIRWRTRGNIRNNNFYFSNH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q03656-1", "uniprot_id": "SKY1_YEAST", "id": "Q03656-1", "name": "Serine/threonine-protein kinase SKY1", "aln": "--MGSSINYPGFVTKSAHLADTSTDASISCEEATSSQEAKKNFFQRDYNMMKKAPAPTKSKLSLALQTSKSSSSAN------------------------------------------GTVQEDTSS--------------------------------KTEDFSTKSIKKKPDSGVESHVSIQSDS--------------GPQSDSDLDSDSSISSCDERN------EESLKDYRPGGYHPAFKGEPYKDARYILVRKLGWGHFSTVWLAKDMVNNTHVAMKIVRGDKVYTEAAEDEIKLLQRVNDADNTKEDSMGANHILKLLDHFNHKGPNGVH--VVMVFEVLGENLLALIKKYEHRGIPLIYVKQISKQLLLGLDYMHRRCGIIHTDIKPENVLMEIGDVEGIVQMVEALDKQKREAK---RLQRHVSRSSDITANDSSDEKWAECQTSMPCGSSSNSKSRSIEKDLSKRCFRRPRR--HTIITGSQPLPSPISSSNFFEMR--------------------------------------------AHFCGSSHNSFSSVSGNRNIPSSINNNSINNGIGIKNSNNSFLNSVPHSVTRMFINEDSNDNNNNDNSKNKNNNNNNS--------------NNNNNEDIMNTPLHEEQLADSLSTFDISNISQSSDTNGPYISNTMDSNSNVSTDINSP--ENLIQIKIADLGNACWYDEHYTNSIQTREYRSPEVLLGAPWGCGADIWSTACLIFELITGDFLFEPDEGH-SYTKDDDHIAQIIELLGELPSYLLRNGKYTRTFFNSRGLLRNISKLKFWPLEDVLTEKYKFSKDEAKEISDFLSPMLQLDPRKRADAGGLVNHPWLKDTLG--------------------------MEEIRVPDRELYGSGSDIPGWFEEVRDHKRH----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9VXN5-1", "uniprot_id": "Q9VXN5_DROME", "id": "Q9VXN5-1", "name": "non-specific serine/threonine protein kinase", "aln": "MFKMKRTRVIRRKAAIIRASKRAFQEKIRKQMESCGVTQMGNASTQQSNVPMDVDADMGRKMSEDGMTDTSNTVKQPS---------------------------------------CSKDQKQLSRKQKPSPSYN-----------HQEQIEQRAKRPKICKKRCKQKRRMPSSLSDDGIAGRKPAKINKYSELSYGSESSMPFEMKQQSNDNQNNNDNAEGSGFDRQESANEYVIGGYHPVAIGDVFV-NRYHVFKKLGWGHFSTVWLCYDTQMDRYCAVKVSKSAQVYKETGIDEIMLFSQMSLHDQHKYR----SHVVGFYDFFEITGPHGRH--ICLVLEVLGDNLLKVIERCFYKGMPISNIKQIAQQVLTGLKFLHEECGIIHTDLKPENVLLASNEVSVRTEIKTAIEVYLKANEGKLSPSSKMTKTAKRRMQAKSK----------KVISFFKNHRRMLRRQGIEDLLYLAERGLIEPITAAMAVSDNLPFIPFGFDG---------------------------------------------FMMMSDADCRTVQNSKLPEMEGMEYKCDRINLCLKSPELFLRYVLDIIKN---------------LDEKELSTQDKR---------------------RRFTQASGRGQTKKNARSRLRLASNAAYTTGTGWRSNRKINLNDIYPIDPANNECDVRVKIADLGNACYFHHHFTDDIQTKEYRALEVILGAGYCETADIWSVACLLWELATGTYLFDTHSKRGKYNLDEVHIAKIVETCGRIPWYLIRKGKHSRNFINSAGKLCNIETLKPLKLANILIRWYGWRTRQSTEFVNFLMPMLQTNPLSRISASKALESHYLCNIALPGIDIDSYYYYSVREIKDCTHTKSERNSDEDSSSCSSIDSSEFSSDEVCYEDDVNEEDIKKLY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . * *: : :* .:* ***:*. *: : ** :.:************. * . *:*: :. : *:. *** ::. : * . : : * *. .* :* : : :*:****.:** * : : *:*: :* * :*:* **.::* * *****:****:*: .: * : . :.: : :.:. . .: : . . . . : : . . . : :*********: ..*:*:.***::**: **::** : *****.**: :** ** :**:... . .*. *: *:*:*:* * :* : .* :: :. * :* ** * ::* . * : :: .: ** .*:: * .* *. :: :: ", "identical_positions": 119, "similar_positions": 132, "identity": "10.66%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101026-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HCL2-1", "uniprot_id": "GPAT1_HUMAN", "id": "Q9HCL2-1", "name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "aln": "MDESALTLGTIDVSYLPHSSEYSVGRCKHTSEEWGECGFRPTIFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWDKFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYVLFIQERDVHKGMFATNVTENVLNSSRVQEAIAEVAAE-LNPDGSAQQQSKAVNKVKKKAKRILQEMVATVSPAMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVK-AATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHIVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSTNVIPDILIIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGCVRVDFAQPFSLKEYLESQSQKPVSALLSLEQALLPAILPSRPSDAADEGRDTSINESRNATDESLRRRLIANLAEHILFTASKSCAIMSTHIVACLLLYRHRQGIDLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRNDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGLGGPTSTPPN--LISQEQLVRKAASLCYLLSNEGTISLPCQTFYQVCHETVGKFIQYGILTVAEHDDQEDISPSLAEQQWDKKLPEPLSWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPEPEYLQKLHKYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKQKRVSVLELSSTFLPQCNRQKLLEYILSFVVL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61586-1", "uniprot_id": "GPAT1_MOUSE", "id": "Q61586-1", "name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "aln": "MEESSVTVGTIDVSYLPSSSEYSLGRCKHTSEDWVDCGFKPTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLSSSRVQEAIAEVAAE-LNPDGSAQQQSKAIQKVKRKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVK-AATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPVFSTLIHKLGGFFIRRRLDETPDGRKDILYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLEGQSQKPVSAPLSLEQALLPAILPSRPNDVADEHQDLSSNESRNPADEAFRRRLIANLAEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSIYAVLNKRCSGGSAGGLGN--LISQEQLVRKAASLCYLLSNEGTISLPCQTFYQVCHETVGKFIQYGILTVAEQDDQEDVSPGLAEQQWDKKLPE-LNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPESEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKQKRVSVLELSSTFLPQCNRQKLLEYILSFVVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F6M7-1", "uniprot_id": "E7F6M7_DANRE", "id": "E7F6M7-1", "name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "aln": "-MDVHMVLGGPDNILLANNPDTGSACLKHPCEDQ-DRSSSPSVLRCVTTTWKEGLLNRKRPFVGRCCHSCTPQSQDRLFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYVLFVLERDVQKDMFARNVVENVLNNSRLECAIVEVANEGVQEDAEPGVDPKAVSKVRRKARGWLQEMVANISPALIRLTGWVLLKLFNGFFWSIQIHKGQLEMVKKAASEYNAPLVFLPVHKSHIDYLLITFILFCHNIKAPHIAAGNNLNIPILSTLIRKLGGFFIRRKMDETSDGKKDVLYRSLLHAYTEELLRQQQFLEVYLEGTRSRSGKPSPARAGMLSIVVDTLCASTIPDVLIVPVGISYDRIIEGNYNSEQLGKPKKNESLWGIACGVFRMLRKNYGCVRVDFTQPFSLKEYLDTQRSRHLQASLTLEQILLPIIIATQPDQAVFNGENENHLNS-DLSDEPWRRQVIADLAKHVLFSASKSSAIMSTHIVACLLLYRHRQGVLLSKLVEDFFNMKEEILSRDFDLGFSGNSEDVVMHALSLLGNCVNVTSTNKNTEFIISPSNTVPALFELNFYSNGLFHVFIADAIIACSALALLREQTPASASEQNPSSTLLSQERLIRRAAGLSHFLSNEVAVALPCQTLYQVFHDAITRLIEYGVLIVAE-EDQEELSP--SEEPWPKKFPEALSWRSDEEDEDSDFGDEQRDRYLKVSPSAEHQEFYTFLQRILTPVLEAYSGAAIFIHSLTSPISERDYTHQLFKYLLTRTERGVSMYGESATHYLVKNTVKTFKELGVLKERREDGVCRLELSSTFIPQANKNKLLQYILGFSLL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.:* * *. ..: . . **..*: : . *:.:*..* .***.*:.**********:****** :::*********************************:**: ****:*.*** .*.****..**:: **.*** * :: *... :.**:.**::**: ******.:**.:*************.***.************ **:* * **:*****:*******:************:**:*******::****:*********::***.**:**:***:***.: **********::**********.* ****:**:*****.:..***:*::************:**.*************.:* **:******** *****:*********: * .: :.* *:*** *** *:.::*.:.. : .: . :* : :**. **::**:**:*:**:****.*******************: **.****** ****:*:******************:.******.:* *.:: **:*:**.***::*********::**** :****** *:*.:: ...: . *:***:*:*:**.*.::**** :::*****:*** *::: ::*:**:* *** :***::** :*: * **:** *.*************:**** ***** * ***:* *****:* *:*****.****:*.::.*:.* :* ::*.:**:*****.*::*.****: ****:** **::**:** ::. *. *******:**.*::***:***.* :*", "identical_positions": 528, "similar_positions": 213, "identity": "63.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101026-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R4F8-1", "uniprot_id": "DNMBP_RAT", "id": "M0R4F8-1", "name": "Dynamin-binding protein", "aln": "MEPGSVVRAIFDFCPSVSEELPLFVGDVIEVLTVVDEFWLLGKKEDVTGQFPSSFVEIVTIPSLKEGERLFVCTCDFISREPNSLSLHRGDLVIIDG-TPTAGWLQGRSSLGARGFFPSSCIHELCLSSQSRQWHSQNMLLQVPEYS---MGQARALMGLSAQLDEELDFREGDVITIIGVPEPGWFEGELEGRRGIFPEGFVELLGPLRTADESVN----------AGSGDDSTLNDEVDVSPEEVESE---GDEDDQQAGTYGIALYRFQALESNELDFEVGDKIRILGTLEDGWLEGRLKGKTGIFPHRFVKLCPSNRSE-ETMALPQGDSFPKNSESSAGEMGDSV-VEEARQDPQECEEETPDSGLPEQTSEEPLDHVAPECVVDKISGQDEDASGS---SPDVDLEGPRAEDPSTPDLSQEVNGISSLPPQVPLQ----PEEEKSQHYLTAGGSRQCPDTFSKLFPLEAKTRNYSSLPPRRTYTQGWSLQKPAPHLHRASSLTASRVNRPGHFS--HTAMASCAQKHQTSAENAASLCCAPERPKRRPGLP-DKEPATEITPASQGD-NLDLDSKLTQQLIEFEKSLSGPSTEPK--------------KIVRRFSIMDFYSEKDIVRGSSNSLPSRNFP-------------ERRKALRPPPPRPHTPTSTSP-HLLVDQSPKPGPPLVVRPSRPAPLPPPTQQRLNTASPKPTSCALPG--------WEAPEKEGSEYTEKSPAQLFPCPSVLARIQDVEHDLDMHTRAQEELNLLLEEKQDESLRAETLETLKSYESTIQSLNLELQQLREMTLLSSQSSSL-AAPSGSVSTEKPEQRMLEKRAKVVAELLQTEKDYIRDLEMCVERVMVPLQQAQVPNIDFEGLFGNMQTVIKVSKQLLAALEITDAV----------GPVFLDHRDELEGTYRLYCQNHDEAISLLDIYEKDERIQKHLQDYLADLKSLYHEWGCTNYINLGSFLIKPVQRIMRYPLLLMELLNSTPESHPDKAPLTSAVLAIKEINANINEYKRRKDLVLKYRKADEDSLMEKISKLNIHSIIKKSSRVSSHLKHLTGFAPQLKDEAFEETEKNFRMQERLIKSFIRDLSLYLQHIRESACVKVVAAMSIWDLCMERG-HHDLEQFEKVHRYISDQLFTRFKERTERLVINPLNQLLNMFTGPYKLVQKRFDKLLDFYNCTERAEKLKDKKTLEDLQSARNNYEALNSQLLDELPKFQQYAQSLFTNCIHGYAEAHCDFVQKALEQLQPLLSLLKASDREGNLIAIFHEEHSRVLQQLQVFTFFPEALP-APRKPFERKTTDRQSSRKALLGMPSYMLQSEELRSSLLARYPPEKLFHVQRNFNAAQDLDVSLLEGDLVGVIKKKDPMGSQNRWLVDNGVTKGFVYSSFLKPYNPRCSHSDSSVVSHSSTESEHSGSSPSFHRQNSSSALTFNSNSMTVSFTSGLPQKQP-------------QDTSP-LRECVPETLGVSSNT---GNPETGPSPCPSDPGFSCQRRPGNPADG-------TREISQPASTLRGCQRRSLHSEVLGY-----PVPGRSDQGSDSIKGTSRACQTAGDRDRGLGSSEAEGNQVYFAIYTFKARNPNELTVLANQRLRILEFKDVTGNTEWWLAEVNGKKGYVPSNYIRKTEYT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6TXD4-1", "uniprot_id": "DNMBP_MOUSE", "id": "Q6TXD4-1", "name": "Dynamin-binding protein", "aln": "MEPGSMVRAIFDFCPSVSEELPLFVGDVIEVLAVVDEFWLLGKKEDVTGQFPSSFVEIVTIPSLKEGERLFVCICEFVSRELNSLSLHRGDLVILDDSAPTAGWLQGRSCWGAWGFFPSSCVQELCLSSRSRRWHAQSALLQAPEYS---LGQARALMGLSAQLDEELDFREGDLITIIGVPEPGWFEGELEGRRGIFPEGFVELLGPLRTVDESVN----------SRSGDDSAVNGEVDVPPEEAESG---GDEDDQQSGTYGIALYRFQALETNELDFEVGDRIQILGTLEDGWLEGCLKGKTGVFPHRFVKLCPSNRTE-ETTAQPQESSFPKDSESSVGKSGDSV-VEEARQEPWECEEERPDYDLPGQAS-VPQDHVAPEWTGDTISGQDKDASGS---SPDVDLERPLAKDLSTPDPSEEVNGVSSQP-QVPIH----PKVQKSQHYLTAGGSHQTSDPFSELVPLEARTRDYSSLPPRRTYAQGWSFQKPASHLQRASSLTASRLDRPSHFC--HPAMASYAQKHQTSTENTASLHDPPERPERRPGLQ-DRGPATDITTASQGD-SLDLDSKLTQQLIEFEKSLSGPSTEPE--------------TIVRRFSIMDFYSEKDIVRGSSNSLPSQAFP-------------ERRKTLRPPPPRPRTPTPISS-HLLVDQSPKPVPTLVVRPSRPAPLPPPAQQRMNTASPKPTSCAHPG--------WEAPEKEDSEHMEKSPAQTFPCPSMLARIRDVEQDLDTCTRAQEELNLLLEEKQDDPSRAETLETLRSYESTIQSLTLELQQLRDMTLLSSQSSSL-AAPFGSVSTENPEQRMLEKRAKVVAELLQTERDYIRDLEMCIERVMVPLQQAQVPNVDFEGLFGNMQTVIKVSKQLLAALEISDAVGMSSCDCLVPGPVFLDHRDELEGTYRVYCQNHDEAISLLEMYEKDEKTQKHLQDYLADLK------GCTNYINLGSFLIKPVQRIMRYPLLLMELLNSTPESHPDKVPLTNAVLAVKEINVNINEYKRRKDLVLKYRKGDEDSLMEKISKLNIHSIIKKSSRVSSHLKHLTGFAPQLKDEVFEETEKNFRMQERLIKSFIRDLSLYLQHIRESACVKVVAAMSIWDLCMERG-HHDLEQFEKVHRYISDQLFTRFKERTERLVINPLNQLLNMFTGPYKLVQKRFDKLLDFYNCTERAEKLKDKKTLEELQSARNNYEALNSQLLDELPKFQQYAQSLFTNCIHGYAEAHCDFVQQALEQLQPLLSLLKATDREGNLIAIFLEEHSRVLQQLQVFTFFPESLP-APRKPFERKTTDRQSSRKTLLGMPSYMLQSEELRSSLLARYPPEKLFHVQRNFNAAQDLDVSLLEGDLVGVIKKKDPMGSQNRWLVDNGVTKGFVYSSFLKPYNPRCSHSDASVASHSSTESEHSGSSPGCHRQNSHSALTFNSNNMTVSFTSGLALTQP-------------QDASP-LKDCAHETLAVSWNT---GHPETGPSTCSSDPGFSCQRRLGNPADG-------ARDISQPASTLRGCQRSSPHSEVVGY-----SVPGRNDQGSDSIKGSARVCQAPEDRDRGVGSSETEGNQVYFAIYTFKARNPNELSVLANQRLRIHEFKDVTGNTEWWLAEVNGRKGYVPSNYIRKTEYT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6XZF7-1", "uniprot_id": "DNMBP_HUMAN", "id": "Q6XZF7-1", "name": "Dynamin-binding protein", "aln": "MEAGSVVRAIFDFCPSVSEELPLFVGDIIEVLAVVDEFWLLGKKEDVTGQFPSSFVEIVTIPSLKEGERLFVCICEFTSQELDNLPLHRGDLVILDG-IPTAGWLQGRSCWGARGFFPSSCVRELCLSSQSRQWHSQSALFQIPEYS---MGQARALMGLSAQLDEELDFREGDVITIIGVPEPGWFEGELEGRRGIFPEGFVELLGPLRTVDESVS----------SGNQDDCIVNGEVDTPVGEEEIG---PDEDEEEPGTYGVALYRFQALEPNELDFEVGDKIRILATLEDGWLEGSLKGRTGIFPYRFVKLCPDTRVE-ETMALPQEGSLARIPETSLDCLENTLGVEEQRHETSDHEAEEPDCIISEAPT-SPLGHLTSEYDTDRNSYQDEDTAGGPPRSPGVEWEMPLATDSPTSDPTEVVNGISSQP-QVPFH----PNLQKSQYYSTVGGSHPHSEQYPDLLPLEARTRDYASLPPKRMYSQLKTLQKPVLPLYRGSSVSASRVVKPRQSSPQLHNLASYTKKHHTS-----SVYSISERLEMKPGPQ-AQGLVMEAATHSQGDGSTDLDSKLTQQLIEFEKSLAGPGTEPD--------------KILRHFSIMDFNSEKDIVRGSSKLITEQELP-------------ERRKALRPPPPRPCTPVSTSP-HLLVDQNLKPAPPLVVRPSRPAPLPPSAQQRTNAVSPKLLSRHRPT--------CETLEKEGPGHMGRSLDQTSPCPLVLVRIEEMERDLDMYSRAQEELNLMLEEKQDESSRAETLEDLKFCESNIESLNMELQQLREMTLLSSQSSSL-VAPSGSVSAENPEQRMLEKRAKVIEELLQTERDYIRDLEMCIERIMVPMQQAQVPNIDFEGLFGNMQMVIKVSKQLLAALEISDAV----------GPVFLGHRDELEGTYKIYCQNHDEAIALLEIYEKDEKIQKHLQDSLADLKSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELLNSTPESHPDKVPLTNAVLAVKEINVNINEYKRRKDLVLKYRKGDEDSLMEKISKLNIHSIIKKSNRVSSHLKHLTGFAPQIKDEVFEETEKNFRMQERLIKSFIRDLSLYLQHIRESACVKVVAAVSMWDVCMERG-HRDLEQFERVHRYISDQLFTNFKERTERLVISPLNQLLSMFTGPHKLVQKRFDKLLDFYNCTERAEKLKDKKTLEELQSARNNYEALNAQLLDELPKFHQYAQGLFTNCVHGYAEAHCDFVHQALEQLKPLLSLLKVAGREGNLIAIFHEEHSRVLQQLQVFTFFPESLP-ATKKPFERKTIDRQSARKPLLGLPSYMLQSEELRASLLARYPPEKLFQAERNFNAAQDLDVSLLEGDLVGVIKKKDPMGSQNRWLIDNGVTKGFVYSSFLKPYNPRRSHSDASVGSHSSTESEHGSSSPRFPRQNSGSTLTFNPSSMAVSFTSGSCQKQP-------------QDASPPPKECDQGTLSASLNP---SNSESSPSRCPSDPDSTSQPRSGDSADV-------ARDVKQPTATPR-SYRNFRHPEIVGY-----SVPGRNGQSQDLVKGCARTAQAPEDRSTEPDGSEAEGNQVYFAVYTFKARNPNELSVSANQKLKILEFKDVTGNTEWWLAEVNGKKGYVPSNYIRKTEYT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F1U2-1", "uniprot_id": "DNMBP_DANRE", "id": "E7F1U2-1", "name": "Dynamin-binding protein", "aln": "MEAGSVVRAVFEFLPSVSEELPLFTGDVIEVLSVVDEFWLLGNKDGVTGQFPTTFVESVTIPGTKAGENLYVCINDFNSAEAGNLPLKRGDVVAAES-SMDSVWMRGHNAWGSRGLFPVSCIKELELSGRSRQLSERSAAVQASELPPHALGQARALMNLHAQLDEELDFREGDVITIIGLPEPGWFQGELDNRTGLFPEGFVELLGPLRSPLEEPEPQTLEQYPDYSNEDEERRAEEEKDEEPPEMEIQQCQEDEEEEEGAIYGIALYEFRALEPGELDFDVGDRIRILASMDDGWLEGQIHSRRGVFPHRFVKIEGQLQTVPQTETLINEISVPKREEECYTPDYTSAEEDHTVPEYGQELSIQQDHTVWDLDYFERREEEQKENNGHNVHSDQSSQERRMTQNQSQVQPQERRRDRPPPPQTQPNRGSSSAHRSVQINRRSSPNMGRPQLPPRPSLHALSNRKYSTGSHASLRQPPPAPITMNQSLNPPNKTSPNSTWTRNNGKYASYNSRNPLSSKSSGEKNRQKKLTRHASVNDADIISGGSSEQQAWPQVQGSNGFPTSQTMGTLALSAKDLEAKLSQQLIEFEKSLPSHSNEATEQSRWEEVSGRLGNKVSRHFSIMDYSDENDIIRGSSHSSIERLLPSTSSPSGSASSSLERRKNLRPPPPRPRVLRPPAPTNTHWSQTNGRITPQPYRPARPAPRPPPPCPHTNAVTPPTTSNPFYNSPDEEEIVEEMEEPEDVLEAEKEMEREQEQYRLLLRLEEVEREIDMYSNTAQELQAMLDEEQDETSRQQALENLEFCSYTMETLTLEQQQLQEMTLLASQPKSLESSPASAANSEDPELRMLEKRTKVIEELLQTEHDYIKDLQMCVKEIIQPLQKKQVQGIDFDGLFGNISSVIDLSRRLNKTLQDTDSI----------GQVFLSYKDQLEDVYKIYCQNHDDAISLLETYEKDENIQKHVLECLEKLRGIYREWGKTNYINLGSFLIKPVQRVMRYPLLLMELLNTTPESHHDRQQLSEAVMSIKEINVNINEYKRRKDLVVKYRKGDEDRLIDKISKLSMHSIIKKSNRVSSHLKHLTGISPQIKDEAFDDAEKRFRLQERLIKSFIRNISLYLQHIRESASVKVLAAISFCDIYTERQQQMDPERFQRAHRCISDKQFTEFKERTEALVITPLTQLLNMFTGPHKLIQKRRDKLLDYDNCKERAERLKDKRVQEELQTARNNYEALNAQLLDELPKFHRAAEDLFTSCVRGFVQAQRDFISLTLGELTPLLQLSGLGGTEGNLVSLFQEEHTRVLDLLQSFSFFPENLPTTVRKTFEKKTLEKQYTKKPQA-PPNYVLQTDEHRAGLLVRYGPENLYQAERNFNAAQDLDVSVLEGDIVGVIKQQDPMGSQNRWLIDNGVTKGFVYSSFLKPYNPRRSQSDVSIESQSSNESGYGGSSPMFSRQNSNSTLTFNQETSTVSFTTATTQNQSNTRPNNESTPRKIRETSSNQRDSLEPGFRNSPNHKEVSETAIRNSREYSEPSHRSSTNHRDSVDSDQNTPTNSRDRLDLSETDSSSSRNSRYEPSSRYQDSKASYGSHQRQNGDYSGQQRRPQYTPEEYIEPEPEPEIDGHQIYYALYSFSARCANELSISANQRVRILEFQDMNGNQEWWLGEAGGRRGYVPSNYIRKSEYT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.**:***:*:* **********.**:****:*********:*:.******::*** ****. * **.*:** :* * * ..*.*:***:* :. : *::*:.. *: *:** **::** **.:**: :. .* .* . :*******.* *************:*****:******:***:.* *:*************: *. . : . :: : * * * * **:::: . **:***.*:***..****:***:*:**.:::****** ::.: *:**:****: . : :* : : *..: * . : :. : : * : . * . ::.. . . * ... :: .* ** .* :: *: :.* . :. . : :.:. .: . . . .. :: . .* . .:::* : ... : * . . : : . **::**:**********.. ..*. .: *:*****: .*:**:****: .: :* **** ******** . . :. : .*. .. **:**** **.. : *:.:* * * * *. :. : :* *:.::*:::* :.: :**: :*:*:**:. * ::** *. . .:::*.:* ***::****:**..** :* .:..:*.** ******:**: ******:***:**:**::.:: *:*: ** .:**:*****:. **.:*::* :*: :*:: * ***.::*:**..*::******:**:**: *****. ***: : * .*: * ****************:************:***** *: *:.**:::****.************:****.*** *::*****.:*******.***********::**:***.*:::**.**:**********::***********.***:**:*: *: ** : * *:*::.** ***: **.****** ***.**.***.*****:**:*** *****: **.****:****:. *:**:*********:*********:: *:.***.*::*:.:*: **: :* :* ***.* . ****:::* ***:***: ** *:**** ** : :*.**:** ::* ::*. *.*:**::* *:.**.** **:*::.:************:****:*****::**********:******************** *:** *: *:**.** :..*** **** *:**** .. :****:. .*. :::*. ::. : * * ... * *:*. .. . :..* :*: : : * . * : * . .:. *. * * :. : .* :*:*:*:*:*:*.** .***:: ***:::* **:*:.** ****.*..*::**********:***", "identical_positions": 717, "similar_positions": 443, "identity": "42.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101026-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10145-1", "uniprot_id": "IL8_HUMAN", "id": "P10145-1", "name": "Interleukin-8", "aln": "MTSKLAVALLAAFLISAALC--EGAVLPRSAKELRCQCIKTYSKPFHPK-FIKELRVIESGPHCANTEIIVKLSDGRELCLDPKENWVQRVVEKFLKRAENS--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "N0GW19-1", "uniprot_id": "N0GW19_DANRE", "id": "N0GW19-1", "name": "", "aln": "MMKLSVSAFMLLICTTALLCANEGEALP---PPQRCQCIKTHSKPPIPKRQVLGLKVTPAGSHCRNEEIIATLKKG-QICLNPTETWVISLKEKFAASATKLAATAAPAQTTTTFSTIMTTN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . *:: : :* ** ** .** *******:*** ** : *:* :*.** * ***..*..* ::**:*.*.** : *** * : ", "identical_positions": 42, "similar_positions": 23, "identity": "34.43%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101026-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O14776-1", "uniprot_id": "TCRG1_HUMAN", "id": "O14776-1", "name": "Transcription elongation regulator 1", "aln": "MAERG----------GDGGESERFNPGEL------------------RMAQQQALRFRGPAPPPNAVMRGPPP---LMRPPPP-FGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMSSMPPPPGMMFPPGMPPVTAPGTPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDG--VKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQVQAQ--VQAQAVGASTPTTSSPAPAVSTSTSSSTPSSTTSTTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSTPAPTATPVQTVPQPHPQTLPPAVPHSVPQPTTAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLEEKIKEPIKEPSEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATAPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPP--------------HKKGMEELKKLRHPTPTMLSIQKWQFSMSAIKEEQELMEEINEDEP--VKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSN-HHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYI------------------------------------------------------EKIAKNLDSEKE-------------------------------------------------KELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDRRGPPPPPTASEPTRRSTK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CGF7-1", "uniprot_id": "TCRG1_MOUSE", "id": "Q8CGF7-1", "name": "Transcription elongation regulator 1", "aln": "MAERG----------GDGGEGERFNPGEL------------------RMAQQQALRFRGPAPPPNAVMRGPPP---LMRPPPP-FGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMGAMPPPPGMMFPPGMPPGTAPGAPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDG--VKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQVQAQAVGAPTPTTSSPAPAVSTSTPTSTPSSTTATTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSAPAPTATPVQTVPQPHPQTLPPAVPHSVPQPAAAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLDEKIKEPIKEASEEPLPMETEEEDPKEEPVKEIKEEPKEEEMTEEEKAAQKAKPVATTPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPP--------------HKKGLEDMKKLRHPAPTMLSIQKWQFSMSAIKEEQELMEEMNEDEP--IKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSN-HHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYI------------------------------------------------------EKIAKNLDSEKE-------------------------------------------------KELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDRRGPPPPPTASEPTRRSTK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LU61-1", "uniprot_id": "A0ABK0LU61_RAT", "id": "A0ABK0LU61-1", "name": "Transcription elongation regulator 1", "aln": "MNNRQSYKDVGRTCQAEGTTNRGYNIMEIVDVFDDQEYWSLEMSTTSRMAQQQALRFRGPAPPPNAVMRGPPP---LMRPPPP-FGMMRGPPPPPRPPFGRPPFDPNMPPMPPPGGIPPPMGPPHLQRPPFMPPPMGAMPPPPGMMFPPGMPPGTAPGAPALPPTEEIWVENKTPDGKVYYYNARTRESAWTKPDG--VKVIQQSELTPMLAAQAQVQAQAQAQAQAQAQAQAQAQAQAQAQAQA-----------------AQAQAQAQAQAQAQAQAQAQAQ--VQAQAVGAPTPTTSSPAPAVSTSAPTSTPSSTTATTTTATSVAQTVSTPTTQDQTPSSAVSVATPTVSVSAPAPTATPVQTVPQPHPQTLPPAVPHSVPQPAAAIPAFPPVMVPPFRVPLPGMPIPLPGVAMMQIVSCPYVKTVATTKTGVLPGMAPPIVPMIHPQVAIAASPATLAGATAVSEWTEYKTADGKTYYYNNRTLESTWEKPQELKEKEKLDEKIKEPIKEASEEPLPMETEEEDPKEEPIKEIKEEPKEEEMTEEEKAAQKAKPVATTPIPGTPWCVVWTGDERVFFYNPTTRLSMWDRPDDLIGRADVDKIIQEPP--------------HKKGLEDMKKLRHPAPTMLSIQKWQFSMSAIKEEQELMEEMNEDEP--IKAKKRKRDDNKDIDSEKEAAMEAEIKAARERAIVPLEARMKQFKDMLLERGVSAFSTWEKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERREKKNKIMQAKEDFKKMMEEAKFNPRATFSEFAAKHAKDSRFKAIEKMKDREALFNEFVAAARKKEKEDSKTRGEKIKSDFFELLSN-HHLDSQSRWSKVKDKVESDPRYKAVDSSSMREDLFKQYI------------------------------------------------------EKIAKNLDSEKE-------------------------------------------------KELERQARIEASLREREREVQKARSEQTKEIDREREQHKREEAIQNFKALLSDMVRSSDVSWSDTRRTLRKDHRWESGSLLEREEKEKLFNEHIEALTKKKREHFRQLLDETSAITLTSTWKEVKKIIKEDPRCIKFSSSDRKKQREFEEYIRDKYITAKADFRTLLKETKFITYRSKKLIQESDQHLKDVEKILQNDKRYLVLDCVPEERRKLIVAYVDDLDRRGPPPPPTASEPTRRSTK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3AU80-1", "uniprot_id": "A0A8M3AU80_DANRE", "id": "A0A8M3AU80-1", "name": "Transcription elongation regulator 1", "aln": "--------------MAENIEAESAQLGEN------------------RMVLQQALRFRNPAPPPAAVLRGPPP---LLRPPPPPFGMMRGPLPPPRSPFGRPPFDPSMPPIPPPGALPPPIGPPHLQRPPFMPPPMGNMPPPPGMIFPPGMPP--SPGAASLP-SEEIWVENNTPEGKVYYYNARTRESAWTKPEG--VKIIQQSELNPLMAAQSGGAAAAPNSAASANVASTTATVVTDT---------------------------------------------VSTQSMSPSHTLSTSPDPSTSPAPTASQPS----ITSVVSEMPPVVSTP------PVSVSVTPVAVVSVPTVTATVTAVQTMPLLH-QSLPPGLP--VAPPAGAIP-FPPVMVPPFRVPLPGMHIPLP-------------------------GMGPPLVPMMHPQLTIAASPMSLAGAIPLPEWSEFKTADGRIYYYNNRTLESTWEKPFELKERDKDSDKARDIHNNIN---LDLKLIDMEAKAD-FGKSKELPREEDMTEEEKATQKGKPVATNPIPGTPWCVVWTGDERVFYYNPTTRLSMWDRPEELVGRADVDRYIQEPP--------------HKRGLDDIKKIGFNK----------------EEIDTAMEDMLDDEP--SKAKKRKKDDVKEPEAAKDVAVEAELKAARDRALVPLEARMNQFRDMLLERGVSAFSTWDKELHKIVFDPRYLLLNPKERKQVFDQYVKTRAEEERKEKKNKLMQSKDDFRRMMEDAKLHTRTTFSEFAAKHSKDPRFKAIEKMKDREVMFTEFMTAFRKKDKEDSKNKVDKVKQDFFDLLSD-HHVDITQRWSKVKDKLETDQRYKAVESSAAREEFYKQYV------------------------------------------------------EKQAKNVDADKE-------------------------------------------------KELERQARIEASLREREREVQRARSEQTKEIDREREQHKREEAIQHFRALMSDMVRSTDTSWSETRRNLRKDHRWETSSLLERHEKEKLFEDHVEALTKRKKEHFRQLLDETPMITLTTAWKEVKKIIKEDPRCMKFSSSDRKKQREFEDYIKDKYIIAKADFRTLLKETKFITYRSRKLIQESDQHLKDIEKVLQNDKRYLVLDCVPEERRKLIMFYIEDLDRRGPPPPPTASEPCRRSTK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KFB8-1", "uniprot_id": "A0A0B4KFB8_DROME", "id": "A0A0B4KFB8-1", "name": "Transcription elongation regulator 1", "aln": "---------------MDASLEESMD-SDG--------------------ASSPITKTEATESPPEAGLNGNGSGSGSTSQETPNYGVAILKEKPSEAHRSKPFNAFSGRPIGEHTAQQQALQQQQLQQQ--------QQPQQPQQQAPS--------GANGVTGPPEIWVETKAEDGRSYYYHAVTRETTWSRPDGPAVKIMTQAEVEEMAKRPAQAAKTEAKAGETSVEIPP-----------------------------------------------------VSSHLTSQPPPHLMSQPPPNAAAPLLSQPPPNVRQQPPPMFQPPGMQAPPGFGQPPFCMPPPTYGFPGGPAPAGAPWGVGIPPWQQQQHMQDKPAKSLIIKPGVID--PAVIARAAEWSEHRAPDGRP--------------------YYFHAGRGESVWEKPQALRDMEAARMAAHSGVAPAVATAPSGLPPHLLPNPMMHMPPGSGPPGFDPHAAFAAAAAAMKANSENTKAAQAAALEKEAKKAAEEKRKKEEEQKKAAASAKQTDKSRPVTSTPIAGTPWCVVWTGDSRVFFYNPSTRTSVWDRPEDLLNREDVDKAVNERPEQLKTPQEKSAEAEQKSGEEANQEQAKSQVQAQQLDQVQRVDADDDDDDEVIKIRTESESSVEEVPTKRVRMISKSKRAEDAALEAEQRAAKERALVPLEMRVTQFKEMLREKDVSAFSTWEKELHKIVFDPRYLLLTSKERKQVFEKYVKDRAEEERKEKRNKMRQKREDFRSLMEEARLHGKSSFSEFSQRNAKDERYRAIEKVRERESLFNEYIVEVRRREKEDKLLKKEQIRKDFLDMLRERHDIERHTRWYDIKKKFESDPRYRMVDS-MYREEYFEDYLHIMKEEKRKEREMREQRERERHRELKSDRKEKDKEKDKGRKDRGRSRSKDKDREHKSSKEKDKDKEEKSKSEKSKKRDTTPEEGEHREESEREERAGSDDSEVARQRENEAEQKQKEREKKLRVEQSIREREKEVQRTLAGHLRDRDKEREHHMREECIGHFTALLTDLVRTPDFTWKEVKRQLRKDHRWELIESLDREDRERKFNEHIDNLMKKKRERFREMLDEISTLQLTSTWKEIKKLIKEDPRYLKYNSD--KGEREFRDYIKDKTMTAKTSLRELLQECKFITHKSSDLIKENPNHLKEIQDILKNDKRYLVLDHMEEERNTIVLGFLEELNKRGPPPPPTASESTRRNK-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : . . : . . .** * :.* . .* :*: *... .:* . *: . .: :**: * * *. *: .:. . *****.:: :*: ***:* ***::*::*:* **:: *:*: : : . : . *.:: . . . * *. :.:. * *. . . :.:* * . . . .: : : * * : * : . : . .* *.*:. . . . * * . .: :. : *: : .. . . : . : : . * . :. . : :.* : *: .::. : . * ::*.:**:: **.***********.***:***:** *:****::*:.* ***: ::* * :* * : :: .: : :: :.*. :. .:: .. . ::.*:*** :**::**:**** *:.**::** *:.*******:***************..*******::*** ******:**:**: * ::**: :**:*::: :::****: :::** *::****:::** :*.*::. *:::***. : ::::.**:::* : *.:: ** .:*.*.*:* **: *:* **: :::*: .* :*: * :** ** *:: *:* *:****:***:: : : :: *:***:* ***.* :* **::*:**:.* :*.:.:* ******** . *:*.::*: *::*:: * *:*:*:**::*** . : **::***:**:****** :*:.*. * :***.:**:** : **:.:* **:* ****::* .**:*. :***:::.:*:********* : ***..::: ::::*::***********. **.. ", "identical_positions": 321, "similar_positions": 326, "identity": "25.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101027-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35239-1", "uniprot_id": "PTN9_MOUSE", "id": "O35239-1", "name": "Tyrosine-protein phosphatase non-receptor type 9", "aln": "MEPATAPRPDMAPELTPEEEQATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARKFDVLRAVELFHCYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSAQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYANFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEVTQHLPRECLPENLGGYVKIDLATWNFQFLPQVNGHPDPFDEIILSSLPPALDWDSVHVPGPHAMTIQELVDYVNTRQKRGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSMAVGNLGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEREGMVPSGHSLLAMDGQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43378-1", "uniprot_id": "PTN9_HUMAN", "id": "P43378-1", "name": "Tyrosine-protein phosphatase non-receptor type 9", "aln": "MEPATAPRPDMAPELTPEEEQATKQFLEEINKWTVQYNVSPLSWNVAVKFLMARKFDVLRAIELFHSYRETRRKEGIVKLKPHEEPLRSEILSGKFTILNVRDPTGASIALFTARLHHPHKSVQHVVLQALFYLLDRAVDSFETQRNGLVFIYDMCGSNYANFELDLGKKVLNLLKGAFPARLKKVLIVGAPIWFRVPYSIISLLLKDKVRERIQILKTSEVTQHLPRECLPENLGGYVKIDLATWNFQFLPQVNGHPDPFDEIILFSLPPALDWDSVHVPGPHAMTIQELVDYVNARQKQGIYEEYEDIRRENPVGTFHCSMSPGNLEKNRYGDVPCLDQTRVKLTKRSGHTQTDYINASFMDGYKQKNAYIGTQGPLENTYRDFWLMVWEQKVLVIVMTTRFEEGGRRKCGQYWPLEKDSRIRFGFLTVTNLGVENMNHYKKTTLEIHNTEERQKRQVTHFQFLSWPDYGVPSSAASLIDFLRVVRNQQSLAVSNMGARSKGQCPEPPIVVHCSAGIGRTGTFCSLDICLAQLEELGTLNVFQTVSRMRTQRAFSIQTPEQYYFCYKAILEFAEKEGMVSSGQNLLAVESQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F716-1", "uniprot_id": "E7F716_DANRE", "id": "E7F716-1", "name": "Tyrosine-protein phosphatase non-receptor type 9", "aln": "---------MMADRLSAEEEQATKQFLEEINKWTSQHGVSPLSWDVAVKFLMARKFDVLRAIELFHSYRETRLREGIVKLQPHKEPLRSELLSGKFTVLGVRDPSGASIALYTAKLHHPSKTGNHVVLQALFYLLDRAVESFETQRNGLVFIYDMAGSNYTNFELDLSKKILNLLKGAFPARLKKVLIVGAPVWFRVPYNLLSLLLKEKLRERVQMVKMADLRQHLPRDCLPEHLGGCLPLDVHNWNLQLLSEQNGRVDPVDELVG--IP--LENTSIHTPGAEAMSLAELMAHLNRAQRSGIYLEYEELRREQPPGTFTCALAAHNQERNRYGDVLCLDQTRVRLKARR-NERSDYINASFMDGYKQKNAYIGTQGPLEKTYGDFWRMVWEQNVLVIVMTTRTDEGGRRKCGQYWPQEEGGQEVYGYIAVVNHRVDNHAHYNQTTLELHNTETFEQRQVTHFQFLSWPDYGVPSSAVSLIDFLGAVKHQQQWAVQAFGTQWRGHPLGPPMVVHCSAGIGRTGTFCALDICLSQLQDVGTLNICQTVRRMRSQRAFSIQTPEQYYFCHAAILEHAQRQGLLSANQ--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** .*:.***************** *:.******:****************:****.***** :******:**:******:******:*.****:******:**:**** *: :***************:***************.****:******.**:*********************:******.::*****:*:***:*::* ::: *****:****:*** : :*: .**:*:*.: **: **.**:: :* *: *:*.**..**:: **: ::* *: *** ***::***:* *** *:::. * *:****** *******:*. * : ::*************************:** *** *****:********* :************ *:..: :*:::*.* *:* **::****:**** ::********************.****** .*::**. ** :*:: :*: **:***************:*****:**:::****: *** ***:***************: ****.*:::*::.:.: ", "identical_positions": 396, "similar_positions": 122, "identity": "66.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101028-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P02008-1", "uniprot_id": "HBAZ_HUMAN", "id": "P02008-1", "name": "Hemoglobin subunit zeta", "aln": "MSLTKTERTIIVSMWAKISTQADTIGTETLERLFLSHPQTKTYFPHF-DLHPGSAQLRAHGSKVVAAVGDAVKSIDDIGGALSKLSELHAYILRVDPVNFKLLSHCLLVTLAARFPADFTAEAHAAWDKFLSVVSSVLTEKYR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06467-1", "uniprot_id": "HBAZ_MOUSE", "id": "P06467-1", "name": "Hemoglobin subunit zeta", "aln": "MSLMKNERAIIMSMWEKMAAQAEPIGTETLERLFCSYPQTKTYFPHF-DLHHGSQQLRAHGFKIMTAVGDAVKSIDNLSSALTKLSELHAYILRVDPVNFKLLSHCLLVTMAARFPADFTPEVHEAWDKFMSILSSILTEKYR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1Q6I6-1", "uniprot_id": "F1Q6I6_DANRE", "id": "F1Q6I6-1", "name": "", "aln": "MSLSAKDKAAVRGFWAKIAPKGEQIGNEAFSRLLLVYPQTKTYFSHWNDLAPGSPSVKKQGKKIVGGLGLAVDKIDDLFNGLLNLSELHAFQLRVDPANFKLLSHCLLVVFAMLFPDDFTAEVHLAIDKFLARVALALSDKYR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** .::: : .:* *::.:.: **.*::.**: :*******.*: ** ** .:: :* *:: .:* **..**:: ..* :******: *****.***********.:* ** ***.*.* * ***:: :: *::***", "identical_positions": 68, "similar_positions": 48, "identity": "47.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101028-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35234-1", "uniprot_id": "PTN5_RAT", "id": "P35234-1", "name": "Tyrosine-protein phosphatase non-receptor type 5", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEEKVEDDFLDLDAVPETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLVSPREESAHEYLLSASRVLRAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVRLTSPDPEDPLSSYINANYIRGYNGEEKVYIATQGPIVSTVVDFWRMVWQER---TPIIVMITNIEEMN-EKCTEYWPEEQVVHDG---------------------VEITVQKVIHTEDYRLRLISLRRGTE-----ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCSPIIVHCSAGIGRTGCFIATS-ICCQQLRREGVVD----------------ILKTTCQLRQDRGGMIQTCEQYQFVHHAMSLYEKQLSLQSSE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P54830-1", "uniprot_id": "PTN5_MOUSE", "id": "P54830-1", "name": "Tyrosine-protein phosphatase non-receptor type 5", "aln": "------------------------MCCSERLLGLPQPVEMEAPDEAEGLPSKQKEMPPPPPPSPPSEPAQKLPPQGAGSHSLTVRSSLCLFAASQFLLACGVLWLSGHGHSWLQNTTDLISSSLTVLNHLGPVAWLGSGTWGIPSLL--LVSLTVSLVIVTTLVWHLLKAPPEPPAPLPPEDRRQSVSRQPSFTYSEWMEEKVEDDFLDLDAVPETPVFDCVMDIKPETDPASLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLVSPREESAHEYLLSASRVLRAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVRLTSPDPEDPLSSYINANYIRGYSGEEKVYIATQGPIVSTVADFWRMVWQER---TPIIVMITNIEEMN-EKCTEYWPEEQVVHDG---------------------VEITVQKVIHTEDYRLRLISLRRGTE-----ERSLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCSPIIVHCSAGIGRTGCFIATS-ICCQQLRREGVVD----------------ILKTTCQLRQDRGGMIQTCEQYQFVHHAMSLYEKQLSLQSSE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54829-1", "uniprot_id": "PTN5_HUMAN", "id": "P54829-1", "name": "Tyrosine-protein phosphatase non-receptor type 5", "aln": "MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPPPPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLVSSLLTLLKQLEPTAWLDSGTWGVPSLL--LVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEH---TPIIVMITNIEEMN-EKCTEYWPEEQVAYDG---------------------VEITVQKVIHTEDYRLRLISLKSGTE-----ERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATS-ICCQQLRQEGVVD----------------ILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQSPE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B4B0-1", "uniprot_id": "A0A8M3B4B0_DANRE", "id": "A0A8M3B4B0-1", "name": "protein-tyrosine-phosphatase", "aln": "------------------------MQDVFESSMAEAPVGEDAPKEQDG-ATSHAHDPLPGIGAALWERVLK--------ASVTAGAFLLLYTLSQLTGLWVLYMLNGYR---AFPAAHKVLDLLQYLLSTSDAYDQQMEIWRVESLLPLIATLFLGVVILGTGTLFCIKTLVPGNQSCFPEDRRQSMSRQPSFTYSEWTDAKQED-FYELDAVPETPVFDCFMDMKTEADPVTLTVKPVGLQERRGSNVSLTLDMCTPGTTEP-YGALLSPREQSTQEYLQNASNLLTPEQLHTRALDDGVLQAEFYETPMNFVDPKEYSIPGVVRKNRYKTILPNTHSRVCLKAKEEGDFLSTYINANYLKGYGGKEKAYIATQGPTVNTVGDFWRMVWQER---CPIIVMITNIEEKN-EKCTEYWPEDSVTCEG---------------------IEITVKQVIQADDYSLRIFTVKSEGE-----ERSLRQYWYTSWPDQKTPDKAPPLLELVQEVEEARKQAPPNSGPVIVHCSAGIGRTGCFIATS-ILCQQLSNEGVVD----------------ILKTTSQLRLDRGGMIQTAEQYQFVHHVLSLYERQLRETSEE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25044-1", "uniprot_id": "PTP1_YEAST", "id": "P25044-1", "name": "Tyrosine-protein phosphatase 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAAPWYIRQRDTDLLGK------------FKFIQNQEDGRLREATNGTVNSRWS-----LGVSIEPRND---------------------------------------------------------------ARNRYVNIMPYERNRVHLKTLSGNDYINASYVKVNVPGQSIEPGYYIATQGPTRKTWDQFWQMCYHNCPLDNIVIVMVTPLVEYNREKCYQYWPRGGVDDTVRIASKWESPGGANDMTQFPSDLKIEFVNVHKVKDYYTVTDIKLTPTDPLVGPVKTVHHFYFDLWKDMNKPEEVVPIMELCAHSHSLNSRG----NPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITERSRHSDRATEEYTRDLIEQIVLQLRSQRMKMVQTKDQFLFIYHAAKYLNSLSVNQ---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :.: : : * . * : * * *.:. .: :*** .*:* :.** *.: . * :.: : * . : ******* .* :**:* ::: :***:* : * * *** :***. * ::* . :* :..** : : :::::: * * :.*:.. *::.* . .. .: *:*******:**** *** . : : * :.:.: * : . *** :* *:** :*: *::*. . : ", "identical_positions": 75, "similar_positions": 89, "identity": "12.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101028-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99M80-1", "uniprot_id": "PTPRT_MOUSE", "id": "Q99M80-1", "name": "Receptor-type tyrosine-protein phosphatase T", "aln": "MGSLGGLALCLLRLLLLGLQRPPLPGAGAQSAAGGCSFDEHYSNCGYSVALGTNGFTWEQINTWEKPMLDPAVPTGSFMMVNSSGRASGQKAHLLLPTLKENDTHCIDFHYYFSSRDRSSPGALNVYVKVNGGPQGNPVWNVSGVVTEGWVKAELAISTFWPHFYQVIFESVSLKGHPGYIAVDEVRVLAHPCRKAPHFLRLQNVEVNVGQNATFQCIAGGKWSQHDKLWLQQWNGRDTALMVTRVVNHRRFSATVSVADTSQRSISKYRCVIRSDGGSGVSNYAELIVKEPPTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGTWAETHIVDSPNYKLWHLDPDVEYEIRVLLTRPGEGGTGPPGPPLTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFNQQQYEAEEVIQTSSHYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEEDVPGAVPLESIQGGPFEEKIYIQWKPPNETNGVITLYEINYKAVGSLDPSADLSSQRGKVFKLRNETHHLFVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKISAPSMPEYDADTPLNETDTTITVMLKPAQSRGAPVSVYQLVVKEERLQKSRRAADIIECFSVPVSYRNASNLDSLHYFAAELKPSNLPVTQPFTVGDNKTYNGYWNPPLSPLKSYSIYFQALSKANGETKINCVRLATKGAPMGSAQVTPGTPLCLLTTASTQNSNTVEPEKQVDNTVKMAGVIAGLLMFIIILLGVMLTIKRR---------------------KLAKKQKETQSG-AQREMGPVASTDKPTAKLGTNRNDEGFSSSSQDVNGFT-------------------------------------DGSRGELSQPTLTIQTHPYRTCDPVEMSYPRDQFQPAIRVADLLQHITQMKRGQGYGFKEEYEALPEGQTASWDTAKEDENRNKNRYGNIISY---DHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGR--------------------VKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGESSNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTAQLCMQYWPEKTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AFL3-1", "uniprot_id": "A0A8I6AFL3_RAT", "id": "A0A8I6AFL3-1", "name": "protein-tyrosine-phosphatase", "aln": "MGSLGALALCLLRLLLLGLQRPPLPGAGAQSAAGGCSFDEHYSNCGYSVALGTNGFTWEQINTWEKPMLDPAVPTGSFMMVNSSGRASGQKAHLLLPTLKENDTHCIDFHYYFSSRDRSSPGALNVYVKVNGGPQGNPVWNVSGVVTEGWVKAELAISTFWPHFYQVIFESVSLKGHPGYIAVDEVRVLAHPCRKAPHFLRLQNVEVNVGQNATFQCIAGGKWSQHDKLWLQQWNGRDTALMVTRVVNHRRFSATVSVADTSQRSVSKYRCVIRSDGGSGVSNYAELIVKEPPTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGTWAETHIVDSPNYKLWHLDPDVEYEIRVLLTRPGEGGTGPPGPPLTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFNQQQYEAEEVIQTSSHYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEEDVPGAVPLESIQGGPFEEKIYIQWKPPNETNGVITLYEINYKAVGSLDPSADLSSQRGKVFKLRNETHHLFVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKISAPSMPEYDADSPLNETDTTITVMLKPAQSRGAPVSVYQLVVKEERLQKSRRAADIIECFSVPVSYRNASNLDSLHYFAAELKPSNLPVTQPFTVGDNKTYNGYWNPPLSPLKSYSIYFQALSKANGETKINCVRLATKG-------------------ASTQNSNTVEPEKQVDNTVKMAGVIAGLLMFIIILLGVMLTIKRR---------------------KLAKKQKETQSG-AQREMGPVASTDKPTTKLSTNRNDEGFSSSSQDVNGFT-------------------------------------DGSRGELSQPTLTIQTHPYRTCDPVEMSYPRDQFQPAIRVADLLQHITQMKRGQGYGFKEEYEALPEGQTASWDTAKEDENRNKNRYGNIISY---DHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGRHPAEHTVGTATLGRAASPGMVKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGESSNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTAQLCMQYWPEKTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKAVRRLEKWQEEYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14522-3", "uniprot_id": "PTPRT_HUMAN", "id": "O14522-3", "name": "Receptor-type tyrosine-protein phosphatase T", "aln": "MASLAALALSLL----LRLQLPPLPGARAQSAAGGCSFDEHYSNCGYSVALGTNGFTWEQINTWEKPMLDQAVPTGSFMMVNSSGRASGQKAHLLLPTLKENDTHCIDFHYYFSSRDRSSPGALNVYVKVNGGPQGNPVWNVSGVVTEGWVKAELAISTFWPHFYQVIFESVSLKGHPGYIAVDEVRVLAHPCRKAPHFLRLQNVEVNVGQNATFQCIAGGKWSQHDKLWLQQWNGRDTALMVTRVVNHRRFSATVSVADTAQRSVSKYRCVIRSDGGSGVSNYAELIVKEPPTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGTWAETHIVDSPNYKLWHLDPDVEYEIRVLLTRPGEGGTGPPGPPLTTRTKCADPVHGPQNVEIVDIRARQLTLQWEPFGYAVTRCHSYNLTVQYQYVFNQQQYEAEEVIQTSSHYTLRGLRPFMTIRLRLLLSNPEGRMESEELVVQTEEDVPGAVPLESIQGGPFEEKIYIQWKPPNETNGVITLYEINYKAVGSLDPSADLSSQRGKVFKLRNETHHLFVGLYPGTTYSFTIKASTAKGFGPPVTTRIATKISAPSMPEYDTDTPLNETDTTITVMLKPAQSRGAPVSVYQLVVKEERLQKSRRAADIIECFSVPVSYRNASSLDSLHYFAAELKPANLPVTQPFTVGDNKTYNGYWNPPLSPLKSYSIYFQALSKANGETKINCVRLATKG-------------------ASTQNSNTVEPEKQVDNTVKMAGVIAGLLMFIIILLGVMLTIKRRRNAYS-----------YSYYLKLAKKQKETQSG-AQREMGPVASADKPTTKLSASRNDEGFSSSSQDVNGFT-------------------------------------DGSRGELSQPTLTIQTHPYRTCDPVEMSYPRDQFQPAIRVADLLQHITQMKRGQGYGFKEEYEALPEGQTASWDTAKEDENRNKNRYGNIISY---DHSRVRLLVLDGDPHSDYINANYIDGYHRPRHYIATQGPMQETVKDFWRMIWQENSASIVMVTNLVEVGR--------------------VKCVRYWPDDTEVYGDIKVTLIETEPLAEYVIRTFTVQKKGYHEIRELRLFHFTSWPDHGVPCYATGLLGFVRQVKFLNPPEAGPIVVHCSAGAGRTGCFIAIDTMLDMAENEGVVDIFNCVRELRAQRVNLVQTEEQYVFVHDAILEACLCGNTAIPVCEFRSLYYNISRLDPQTNSSQIKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLPLDRCLPFLISVDGESSNYINAALMDSHKQPAAFVVTQHPLPNTVADFWRLVFDYNCSSVVMLNEMDTAQFCMQYWPEKTSGCYGPIQVEFVSADIDEDIIHRIFRICNMARPQDGYRIVQHLQYIGWPAYRDTPPSKRSLLKVVRRLEKWQEQYDGREGRTVVHCLNGGGRSGTFCAICSVCEMIQQQNIIDVFHIVKTLRNNKSNMVETLEQYKFVYEVALEYLSSF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q0Y4-1", "uniprot_id": "A0A8M9Q0Y4_DANRE", "id": "A0A8M9Q0Y4-1", "name": "protein-tyrosine-phosphatase", "aln": "MDQRNYFALLLLVLHVQLTFGEFFPGS--------CSFEEHYSNCGYSVALGTNGFAWEQVNTWERPSMDAAVPTGSFMMVNASGRASGQKAHLLLPTLKENDTHCIDFHYSLSSRDGTSPGTLNVYIKVDGGPQGNPIWNASTPVTEGWVKAELAISTFWPNSYQVIFEAVSVQGHPGFIAVDEIHVLAHPCRKTPHFLRLQNVEVNVGQNATFQCIAGGKWSQHDKLWLQQWNGKDTSLMVTRVVNHRRFSATVSVTDTSQRSTSRYRCVIRSDGGSGVSNYAELSVKAPPTPIAPPELLAVGATYLWIKPNANSIIGDGPIILKEVEYRTTTGNWAETHVVDAPTYKLWHLDPDVEYEIKVLLTRPGEGGTGPPGPPLITRTKCADPVNGPQNVNVVDIRARQLTLQWETFGYAVTRCHSFNLTVQYQYVFNQQVYATEDLIPTSSHYTLRGLRPFVTVRLRLVLANPEGSKESEEIVKQTEEDVPGPIPMESIQTGPYEEKIFMQWKAPNETNGVITLYEIAYKALSSLDPTADLTTQRGRVFKLQNETHHLFVGLYPGTTYFFTLKASTNKGFGPPVTTRITTKIAAPSMPEYETDSPLNETDTTITVLLKPAQSRGAPVSSYQVVVQEERKQKVRRATDVLECFPVPVSFRNASILDSPHYFAAELPPVSLAVVQPFTIGDNKTYNGYWNAPLSPAKSYSIYFQALSKANGETKINCVRLATKVVIGRGQNTTPYILVIPSEGASTQNSNDIEPEKQVDSTVKMAGVIAGILMFVIILLGLLLTFKRREIHTWRTLSVGRNAYSYSYYLKLAKKQKETASSSTQREMGPVGTADKSTGKVSTLHKDDPFSTSNQDLNGFSSSSPCSFSIQGKAIQSKTLLNSYYSVSKEPVPATASIDGSHSEMSQPSMTIQTYPYGGCESVEMSYQAGQFQPAIRVADLLQHITQMKCGQGYGFKEEYEGLAEGQTAPWETAKKEENRNKNRYGNIIAYPTDDHTRVRLQPLEGDPHSDYINANYIDGYHRPRHYIATQGPMQETVRDFWRMIWQENSASIVMVTNLVEVGR--------------------VKCVRYWPDETEVYGDIKVTLIETEPLAEYVIRTFTVQKKGHHEIREIRQFHFTSWPDHGVPCYATGLLGFIRQVKFLNPPDAGPIVVHCSAGAGRTGCFIAVDIMLDMAESEGVVDIFNCIRELRSQRVNMVQTEEQYVFVHDAILEACLCGNTAIPVCEFRAIYYNISRLDPQTNSSQVKDEFQTLNIVTPRVRPEDCSIGLLPRNHDKNRSMDVLAVDRCLPFLISVDGESSNYINAALMDSHKQPAAFIVTQHPLPNTMADFWRLVFDYNCSTIVMLNEMDAAQLCMQYWPEKGSCCYGPIQVEFISADIDEDIINRIFRICNMARPQDGYRLVQHFQFIGWPAYRDTPLSKRSILQLVRRLAKWQEQYDGGDGRTVVHCLTGGGRSGTFCAICSICEMIQQQNIVDVFHTVKTLRNNKANMVETMEQYKFCYEVALESLNGF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . :** ** :**: ***:*****************:***:****:* :* ***********:**************************** :**** :***:****:**:*******:**.* *****************: ******:**::****:*****::********:****************************************:**:******************:**:*** *:******************* ** *********************************************.*****:**:*.**************:****************** *********:*****::*************.**********:************* * :*::* *************:*:****:*:**** ****:* ********.:*:**** **:****::***.************* ***:.****:***::***:****:**************** **:**** ***********:***:*******::*:***********:************ **:**:*** ** ***:*::***.****:**** *** ******* * .*.*.****:***********.**** *************************** ******* :*******.**********:***:*****::**:*** ********* *. :*******.::**.* *:.: ::*: **:*.**:***: ***:.*:***::****:** *:.***** .******************* ***********.*.*****.*:***::************:* **:**** *:*********************************:************************* *********:*******************************:*****:* *********************:*********:********************:* ******.*********:****:****:*******************************::***************:*************************************.:********************************:*********:*************::*******:**:******** * *********:*********:****************:***:*:********** ****:*: **** ****:*** :********.*************:*********:**** ********:*****:***** ****** *..*", "identical_positions": 1198, "similar_positions": 160, "identity": "77.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101101-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A582-1", "uniprot_id": "D4A582_RAT", "id": "D4A582-1", "name": "", "aln": "MQKRQGYCSYCRVRYPNLEQHLFSAQHRSLTRQCRRRTITNNTLMERFLQDVIRHHPYNYQDSRPAPNEAAAAAAAAAAAAAAAAAAADDPGSPE-VVILDDSDD------DSGAERNSEDSASVEEIDCRPGTSQE-RPEAAVRPSVIQKLERGQQQSLELAHKVESGVKKVNSVGVVQATTSGKKLVRPPVICNAPASSLPSGSFERPVAANSVPRLVLAVASDSFPACDTENLEKYFDSPDQGPSNPS----------SQPKTKDPKKK-LSINLDKLLSQRNLRAKGASFSPVVRVRELTGPELCSVRAESSSELEAGTAGNPNETDTPPEQ-ALEGAIPKRREAFRSNIVHPQEETHLVLNKSTLLKQKRSVSSEERFDHRSLQAVPGPSQAAVHDLSLLEEEEEEE----QEEEEEQEEEQQEEEEEGVDQEDVSYESRGSDTSFDCGSSCQSLSALSEPTTREIDVSEETHADAQPRNETPTVSGATSDNGSTSRRVATTH----SQVITQNIQFISLVDESYESSGSEVNFDGDDSLPSTSHRPSQPVEVV-----VPLRLVDKSYGSGSSEPCEDS----GSSADETPTAAGQQNPLNSAHANLVDENYGS----SSFSSDS--DAALDRPHMPVQERSPRDRAVEQENED-QPSSAEARPDRDSSLVTVADEAQREAEEINLPNQKNTSLGDTNCESHGPDVGFHADAQLEADQ--SPVNPEEVDLDLENQSVHSGISNLSFDSHAS-YQSANDQPQGAWGEVNLDELNVDMEVKSSGCSSSELTFDSDSPLLSVTERSLLDFEGINEDDFNLEDESCVSSSSDITFDSDIPNDSVADQPQVAVYEEEPVGLENKSNESCVSGITFDSDIPLHSGNDHPEVAVKEVIIQEEENVHLKGKNDNPSGSEICLDSNAPLHSVTNS-DVAVKKINPPKEEQVHIEQIEQKESEPTDSELHLDSNS-FNSKPGCSEDPIILR--------------VSETRLDSRVPFQSVIRRCEVVVKNVCLQKEKHAELTSKSIESPSEISSAST--TAPPVTEPYVGKKAKRKTKHLEEVNSDDEYGGCPPTFNSDVFPWSMTEKPQPVALKEGYADSKDERTELRGMEENLNTAGRLDSVISQPQLALKENCVELTDTDGKPSDSKASVDSTGHFHSLPKQEFDVITKMNEWKKEAKVLEKKISELIYSKIIHDSNVSFRSAMDQLELALKQITLDGDDQVPLED-NSQDACSETNLDSNVSAQAVVEPPE--VTVLEPEHVDLERRNNVSCDSQVSIDSNDSVQLEADQNSERGENRSQKNTD--DMEGKREDAQGFGITCDSNVPQPLAG-QIEVVQETDRWKDHVDLEDKIVESSDSKINFHSDEPLQAVTNATQEPVQEINLL-RGHASLNGNGCESYGSGIVPVSNVIFCSVIQKPQRLQKGHASLKVKSSNPCGPEVSVDSREGPEMSFDSNDPCQSAAGHLQKPVKEIN-LKEDHIYLEDKSYKLVDFEPTYDSDDPAQFVTDPSVEAVSIKEVNLQKENHDDLENENFQPCCSEVAYNSGVHLQSEVEPPQVACKEADLDKR-ELDIEDKCSVSCEPEVVYDSDVSFQIVVNQVQTSDGETDSPQVVFVDVVSSDSDCDREVISDSNIPLQPETMPPQMTIKETSDVNTDSLGS-AADEKYYCKFCGCDYEAS-QSVTNQSKESFKIINRKNDYIILGDSTCPSCGHELNFNVDPSDQPTTCQLQEPDA---NVIDPEKKNYESKSSKRKYDWEDTTQPMTRQLQKTGEAISLRKDPKYRSKKDRPWGSSSFTADRAAYAVSVIRQTAVKRSFSKRAHTVLKTASPNSYGSELNFQYDASLQSDPDQPQ--PKRAGPRKKVTFDLRVTKYEYPPDPVYSEG--------EEVAEGDPKE-LVHEASPQVQGSPSSVRKTSSQ-GRGDDVKTHMQG---CQSRFYSYYDGGSENKKILLSEEEKTTWSDLN--QNTKSIQCVGG------KVGDTGDFSVALGKPS--CSLPEG-HQQPGQVTSQNQVGGVRGGTQASSG----KKRKITEQEDDSPKRKY----FRHDSQKKKKAQTGTTELPEPQTKVLEPVQPDSLVYIFSSLSMK--EDQSLNPPKK--KPGS-DRDLRGAYSCKEHTSS--GPRRKRTVINPPQNLRVPDVGRCEVVGLDLNRRDPRSNAEENGANRQNLASTSFMTTPKRSVLKFHR--TSQSSFLKKSEDVGATQVPKD-NFQQTLVNRDGAKKFRKSIRKEVFENKNQRKFWKKKMVAAN-KSCLIKNAYETAVLQKKSRVASEKLALWIQLKATDITRKYVSKCHGVVSRRNQSKTVLIRMQLRKKKIVARKIKEAKRAAEALRLES-------------RTVLPAVLPAVLPAVLP---------------------------------------------------------------------------------------------AVLP--------------AVLP-----------------------------------AVLPAGAEKQQLSTPAVPAELPALPAHLSDAGGVKRYRKTYYRKRKR-LLPVREYDLRSLSSTPNTDRMVTRLASKSKSNEAK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SS00-1", "uniprot_id": "ZDBF2_MOUSE", "id": "Q5SS00-1", "name": "DBF4-type zinc finger-containing protein 2 homolog", "aln": "MEAQS-----YQEVMKNNGQHLFSSQHRSLTRQSRRRTATNNTLMERFLQDVLRHHPYNYQDNRSAPNEPEAAAAAAAAA---------DPGSPEVVVVLDDSDEKEDDTADSGAERNSEDSGSVEEIDYRPGTSQE-HAEVAVRPSVIQKLERGQQQSLELAHKVESGVKKVNSVGVVQATTSGKKLVRPPVICNAPASSLPSGSFERPVAANSVPRLVLAVASDSFPACDTENLETYFDSPDQGPSNPS----------SQPKTKDPKKK-LSINLDKLLAQRNLRAKGASFSPVVRVRELTGSELCSVRAESS-ELEAGTAGNPRETDTLPEQ-AREGAIPKRREASRSNTVRPQEETRLVLNKPTLLKQKRSVSSEERFSCGSRQAVPGPSQAAVRDLSLLEEEVEEEKQEEEEEEEQEEEEEHEEEEEGVDQEDASYESRGSDMSFDCGSSCQSLSALSELTAREINVSEETHAYSQPRNETPTVSGATSDNGSSSR-----------QVITQNIQLISLVDESYESSGSEVNFDGDDSLPSTSHRPPQPVEVV-----VPLRLVDKSYGSGSSEPCEDS----GSSADETPAASRQQNPVRNTHANLVDENYGS----SSFSSDS--DAALDHPQVPVQEGSPRGRAVGQGNEE-QPSSAEAHPERDGSLETVAHELQRESQEINLPNQKNTSLGDMNCESHGPEVGFHADAQLEADQ--SPVNPEEVDLDLENQSVHSGISNLSFDSNAS-YQSANDQPQGAWGEVNLDELNVDMEVKSNGCSSSELTFDSDSPLLSVTERSLLDFEGLNEDDFNLEDENCVSSSSDITFDSDIPDDSVADQPQVAVYEEEPVGLENKSNESCVSGITFDSDIPLHSGNDHPEVAVKEVIIKEDENVHLEGKNDNPSGSEICLDSNVPLHSVTNS-DVAVKKINPPKEDQVQIEQIEQKENEPTDSELNLDCNS-VNSKPGCSEDPIILR--------------VSETRLDSHVPFQSVIRKCEVVVKNVCLQKEKHAELTSKSTESHSEVSSAST--ASHPVTEPYVGKKAKRKTKHLEEVNSDDEYGGSQPTFKFDVFPRTMTEKPQPAALKEGHADPKDKITELRGMAVNVNTADCLDSVLSQPQLASNENCVELKDTDGKPSDSKASADSTGHFHSLPKQEFDVVSKMNEWKKEAKVLEQKISDLIYSKIIHDSNVSFRSAMDQLELALKQISLGNNDQVSLED-NSQDTCSETNLDSGFSVQAVVEPPEPEVTVLEPEHVEQEGRNNVPCDSEVSVDANGSVQLEAGQHSESGENRSQKDTD--DTEGKRDDAQGFGITCDSNVPQPLAG-HIEVVQDIDHWKDHVDLEDKLGESKNSKVNFHSDEPLQAVTNATQEPVEEINLP-RGRASPNGNGCEPYGSTIVPVTNVIFCSVIQKPQRLQKKCTSLKENSSNPC-PEVNVDSCDGPEVSVDSNDPCQSVAGHLQKPDKEMN-LKEDHIYLEDKSYKLVDFEPTYDSDDPVQFVTVPSVEAVSIKEVNLQKENPDDLENENFQPCCSEVACNSAVHLQSEADPPQVACKEADLDKK-ALDIEDKGSVTCVPEVVYDSDVSFQIVVNQVQTSDGETDSPQVVFVDVVSSDSDCDREVISDSNIPLQLE--PPQMTVKETSDINTDSLGS-AANEKYYCKFCGCDYEAS-QSVTNQSKESFKIINRKNDYIILGDSTCPSCGHELNFNVDPSDQPTTCQLQQPDR---NFIDPEDKNFGSKCPKRKLNWEDTAHPVTHQLQKTGEATSLRKDQKNRFKRDRGWESSSFAGDHAAYAVSVIRQTALN-----------------SCGSELNFQDDTFYHSDIDPPQ--PKKKGQGKKVTFDLRVTKYEYPPNPMYGEG--------EEVAEDDLKEVVVHEASPQGQAPPSIVGKTCPQ-GREDDVKTNTQA---CQGYFYSYYDGGSETKKILLGEEEKTIRSDLN--QNTTSIQHVKG------KVGDTGDFSVDLGKQS--CSLAEGLHQQHGQVTSQNQV-EVRCGIQASSG----KKRKITEQEEDSPKRKC----FHHDSQKKKKAQAGITELPEPQTKVLEPVQPDSLVYIFSSLSMK--EDQSLNPPKT--KPGS-DSDLPHIYSCREHTSS--GPRRKRTVINPPQNLMVPEVG------IDLNRHDPKPNAGDDSAKRQNLVSTSFMAMPKKSVLKFQR--TNQSSFLKKSEDVGATQVPKD-NFQQTLVNRDGAKKFPKSVKKEDLESQNQRKFWKKKMVAAN-KLCLIKNAYKTMVLRKKSKLASEKLAIWIQLKATDIIRKYVSRCHGLMPRRHLSKTVLIRMQLRKKKIVARKIKEAKRAAEALALKLSRPSCPPRAPCPPRALCPPRAPCPPRALCPPRAPCPPRALCTPRAPCPPRALCTPRAPCPPRALCTPRAPCPPRALRAPCPPRALCSPRAPCPPRALCPPRAPCPPRAPRAPCPPRAPCPPRAPCLPRAPCPPRAPCPPRAPCLPRAPCLPQAPCPPRALCLPRVSCPPLPLCAPCPPCAPVLPAGAEEQ-LSTTAGPAELP---AHLSNAGGIKRYRKTYFRRRKR-LLPVREYDLRSLSSTTNTDRMVTRLASKSKSNEAK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCK1-1", "uniprot_id": "ZDBF2_HUMAN", "id": "Q9HCK1-1", "name": "DBF4-type zinc finger-containing protein 2", "aln": "MQKRQGYCSYCRVQYNNLEQHLFSAQHRSLTRQSRRQICTS-SLMERFLQDVLQHHPYHCQESSSTQDETHVNTGSSSEVVH-----LDDAFSEEEEEDEDKVEDE-----DATEERPSEVSEPIEELHSRPHKSQEGTQEVSVRPSVIQKLEKGQQQPLEFVHKIGASVRKCNLVDIGQATNNRSNLVRPPVICNAPASCLPESSNDRPVTANTTS-LPPAAHLDSVSKCDPNKVEKYLEQPDGASRNPVPSSHVETTSFSYQKHKESNRKSLRMNSDKLVLWKDVKSQGKTLSAGLKFHERMG-TKGSLRVKSP----SKLAVNPNKTDMPSNKGIFEDTIAKNHEEFFSNMDCTQEEKHLVFNKTAFWEQKCSVSSEMKFDCISLQSASDQPQETAQDLSLWKEE-------------------------QIDQEDN-YESRGSEMSFDCSSSFHSLTDQSKVSAKEVNLSKEVRTDVQYKNNKSYVSKISSDCDDILHLVTNQSQMIVKEISLQNARHISLVDQSYESSSSETNFDCDASPQSTSDYPQQSVTEVNLPKEVHIGLVDKNYGSSSSEVSADSVFPLQSVVDRPPVAVTETKLRKKAHTSLVDN-YGSSCSETSFDCDVSLESVVDHPQLTVKGRNLKGRQVHLKHKKRKPSSAKAHLDCDVSLGTVADESQRAVEKINLLKEKNADLMDMNCESHGPEMGFQADAQLADQSQVAEIERQKVDVDLENKSVQSSRSSLSSDSPASLYHSAHDEPQEALDEVNLKELNIDMEVRSYDCSSSELTFDSDPPLLSVTEQSHLDAEGK-ERHIDLEDESCESDSSEITFDSDIPLYSVIDQPEVAVYEEETVDLESKSNESCVSEITFDSDIPLHSGNDHPEVAVKEVIQKE-EYIHLERKNDEPSGSEISSDSHAPLHSVTNSPEVAVKKLNPQKEEQVHLE---NKENEPIDSEVSLDYNIIFHSVTGRSEDPIKEISLHTKEHMYLENKSVFETSLDSDVPLQAATHKPEVIVKETWLQREKHAEFQGRSTEFSGSKTSLDSGVPHYSVTEPQVAVNKINRKKQYVLENKNDKCSGSEIILDSNVPPQSMTDQPQLAFLKEKHVN--------------------------------------LKDKNSKSGDSKITFDSE--------QLQEAVKKIDQWKEEVIGLKNKINEPSTYKLIHHPDVSVQSVADQPKVAIKHVNLGNENHMYLEVKNSQYSCSEMNLDSGFLGQSIVNRPQ--ITILEQEHIELEGKHNQCCGSEVSFDSDDPLQSVADRLRETVKEISLWKDEEVDTEDRRNEAKGFEIMYDSDVLQPVAGQPEEVVKEVSLWKEHVDLENKIVKPTDSRINFDSHEPLQSVTNKIPGANKEINLLREEHVCLDDKGYVPSDSEIIYVSNIPLQSVIKQPHILEEEHASLEDKSSNSY----------SPEESSDSNDSFQAAADELQKPVKEINLWKEDHIYLEDKSYKLGDFDVSYASHIPVQFVTDQ--SSVPVKEINLQKKDHNDLENKNCEVCGSEIKCHSCVHLQSEVDQPQVSYKEADLQKEEHVVMEEKTDQPSDSEMMYDSDVPFQIVVNQFPGSVKETHLPKVVLVDLVPGDS--DYEVISD-DIPLQLVTDPPQLTVKDISCINTECIDIEDKSCDFFGSEVRCNCKASTPSMTNQCKETFKIINRKKDYIILGEPSCQSCGSEMNFNVDASDQSMTYESQGPDEKMVKYIDSEDKSCGYNGSKGKFNLEDTSHRTTHRLQKAHKEASLRKDPRNAGLKGKSCQSSASAVDFGASSKSALHRRADKKKRSKLKHRDLEVSCE-PDGFEMNFQCAPPLPSDTDQPQETVKKRHPCKKVSSDLKEKNHDSQSSSVLKVDSVRNLKKAKDVIEDNPDE-PVLEALP--HVPPSFVGKTWSQIMREDDIKINALVKEFREGRFHCYFDDDCETKKVSSKGKKKVTWADLQGKEDTAPTQAVSESDDIVCGISDIDDLSVALDKPCHRHPPAERPPKQKGRVASQCQTAKISHSTQTSCKNYPVMKRKIIRQEEDPPKSKCSR--LQDDRKTKKKVKIGTVEFPASCTKVLKPMQPKALVCVLSSLNIKLKEGEGLPFPKM--RHHSWDNDIRFICKYKRNIFDYYEPLIKQIVISPPLSVIVPEFERRNWVKIHFNRSNQNSSAGDNDADGQGSASAPLMAVPARYGFNSHQGTSDSSLFLEESKVLHARELPKKRNFQLTFLNHDVVKISPKSVRNKLLESQSKKKIHGKRVTTSSNKLGFPKKVYKPIILQQKPRKASEKQSIWIRTKPSDIIRKYISKYSVFLRHRYQSRSAFLGRYLKKKKSVVSRLKKAKRTAKVLLNSS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPPAGAEELSSAMANPPPKRP-VRASCRVARRRKKTDESYHGRQKGPSTPVRAYDLRSSSCLQQRERMMTRLANKLRGNEVK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PZU1-1", "uniprot_id": "A0A8M9PZU1_DANRE", "id": "A0A8M9PZU1-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPLGEGPKPSAKNAERRPTDISGRTRREEPVAGPSSYQRQ---------------------------------------GYCSCCQVLYNS-----VEQHILSAQHREVVRASRANVSSG-------------------SLLERFLQDVLQHHPHHYSDTRPSHADLPLLTTPLVP-------------------KEVLSEVYCGSDDDGVSVGTREEMPTSDEESCQMLQVATAGPAVTTDFTANTHLQTASQKGKMVP------------------EQPPPEKYSPTQGFLHRTSGS----------------------------------------------------------------------------------SANDKLHTSQFTLPVQRESSHTHPSRHPPSEGAPVSKTG---------------AVEHRKAHKKTNRENEGSDTIKASCAPPAAKCITSKDQPETFRS------------------------------------------------------------------------VTEESTKWISALPPWKGLHREQTFSNLSDQIRDVIEEVIEK-------------------------YCYGLNVDQQEEDGSFLFGPQ--------------------------------------------------------------------------------------------------------------------------------------------SVSDSKGSEEWDN-------------------------------------------------------AIQVALGKTKGEEKNLAQLLEVHIDLEDQTYQT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QLDTALNTVGTPEEP----------------------------------------------------------------------------KQNAEDNVIPDLP-------------------------------------------HIPQSFVGKTWTQVMFEDDIKIDSIVREFQQGQFRCYFD--SESLAMYGKHCKKRRKNKKRDNKEQTETVELNP-------TDILPLIEHNEEDPKHSAVLVRKTRQKYYRQASRCQVVKVSHGTQTIPLSCPMVRSKPTQETFPSTYNDEPQQCPSPERTPEMKTRLCALKLPTSYCKIMSPLQPKTVVYVLSSPDGGQGISKPTPIKKAGRKRKSCDSDGGLKYKYKKTPLKFYDPLTNRILKSPPKGMSSPPNSK----SLSHVRQLFRSLSPDINKERQGQSPGSSRKGRGR--------RNMVDLCTTTSDSILESGGPSEPSSSLTSSRRAIFTRSSISSRSCLLLGHLTPSAHVDDSSKAHSHSCAGSSYKVGGMEQEEHIQQTSVDQTPIRRSLRRAGLLTPAKRPSAPPYRTKRKSAKQQRKVKSQGSLQRSVSSHISAECRTSPRN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KSPGRASLRSSASSNLAIQP--------------------------VITSSSKQINTMLSASQQKRGRGRTATVHTAD---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : *: ..: . : : . :* :. : : : *: : .*: :. :.: ..: *::. :.:* . *..: *: : *. . .:* ***:.. . . *:: .** ** : ::.. :**. : . :. . . * :: *::..:: ::. : . .* :: ** .:.* :. : .. :*:*. .: . * .: * * ::: .. . :*.: * ::. . : :* . : : :: .. .... :: * *:*. :.: *: :.:* .. . * . .. : *:: * ** ***::*: :*:.: : . :: : .:* ** : . * * ** .* **:* . :. * .*:* .*. : :* . . :: : . :. . . :: : :*: *. : . *: : * .: .. . : : *.: ::* . *::.*:**.::* ::** . .: * : * * * . :. . * :: : .** .: * : * .. : : . . *. . . : . . *. : *.. . . * .: . * :. : .: . . : : .. : ::: :. *: . :: * ::. ::.: : :.. : ..* . : . . * . ::.: . : .* * *. .: ", "identical_positions": 99, "similar_positions": 297, "identity": "3.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101102-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54827-1", "uniprot_id": "AT10A_MOUSE", "id": "O54827-1", "name": "Phospholipid-transporting ATPase VA", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERELPA-AEESASSGWRRPRRRRW--EGRTRTVRSNLLPPLGTEDSTIGAPKGERLLMRGCI---------------QHLADNRLKTTKYTLLSFLPKNLFEQFHRLANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAVTAIKDLWEDYSRHRSDHEINHLGCLVFSREEKKYVNRYWKEIRVGDFVRLCCNEIIPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDLSRFRGYIMHSNGEKAGLHKENLLLRGCTIRNTEAVAGIVIYAGHETKALLNNSGPRYKRSQLERQMNCDVLWCVLLLVCISLFSAVGHGLWVRRYQEKKALFDVPESDGSSLSPATAAVYSFFTMIIVLQVLIPISLYVSIEIVKVCQVYFINQDIELYDEETDSQLQCRALNITEDLGQIKYIFSDKTGTLTENKMVFRRCTVSGIEYSHDANAQRLARYQEADSEEEEVVSKVGTISHRGSTGSHQSIWMTHKTQSIKSHRRTGSRAEAKRASMLSKHTAFSSPMEKDITPDPKLLEKVSECDRFLAIAR-HQEHPLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRQKVRVRFELKSPVKTIEDFLRRFTPSRLASG--CSSIGNLSTSKSS-HKSGSAFLPSLSQDSMLLGLEEKLGQTAPSIASNGYASQAGQEESWASECTTDQKCPGEQREQQEGELRYEAESPDEAALVYAARAYNCALVDRLHDQVSVELPHLGR-LTFELLHTLGFDSIRKRMSVVIRHPLTDEINVYTKGADSVVMDLLLPCSSDDARGRHQKKIRSKTQNYLNLYAVEGLRTLCIAKRVLSKEEYACWLQSHIEAEASVESREELLFQSAVRLETNLHLLGATGIEDRLQEGVPETIAKLRQAGLQIWVLTGDKQETAINIAYACKLLDHGEEVITLNADSQEACAALLDQCLSYVQSR---NPRSTLQNSESNLSVGFS--FNPVSTSTDAS----PSPSLVIDGRSLAYALEKS--LEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPRFRYLERLLIVHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFYCGFSASAMIDQWYLIFFNLLFSSLPQLVTGVLDKDVPADMLLREPQLYKSGQNMEEYRPRAFWLNMVDAAFQSLVCFFIPYLAYYDSDVDVFTWGTPVTAIALFTFLLHLGIETKTWTWLNWLACGFSTFLFFSVALIYNTSCATCYPPSNPYWTMQTLLGDPLFYLTCLIAPIAALLPRLFFKALQGSLFPTQLQLGRQLAKK-----------------PLNKFSDPKETFAQGQPPGHSETELSERKTMGPFETLPRDCASQASQFTQQLTCSPEASGEPSAVDTNMPLRENTLLEGLGSQASGSSMPRGAIS---EVCPGDSKR---QSTSASQTARLSSLFHLPSFGSLNWISSLSLASGLGSVLQLSGSSLQMDKQDGEFLSNPPQPEQDLHSFQGQVTGYL----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2JWQ8-1", "uniprot_id": "A0A0G2JWQ8_RAT", "id": "A0A0G2JWQ8-1", "name": "Phospholipid-transporting ATPase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERESAA-AEEPASPGRRRPRRRRW--EGRTRTVRSNLLPSLGTEDSTAGASKGERLLMRGCI---------------QHLADNRLKTTKYTLLSFLPKNLFEQFHRLANVYFVFIALLNFVPAVNAFQPVLALAPVLFILAVTAIKDLWEDYSRHRSDHEINHLGCLVFSREEKKYVNRYWKEIRVGDFVRLCCNEIIPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDLSRFRGCIIHSNGEKAGLHKENLLLRGCTIRNTEAVAGIVIYAGHETKALLNNSGPRYKRSQLERQMNCDVLWCVLLLVCISLFSAVGHGLWVRRYQEKKALFDVPESDGSSLSPATAAVYSFLTMIIVLQVLIPISLYVSIEIVKVCQVYFINQDIELYDEETDSQLQCRALNITEDLGQIKYIFSDKTGTLTENKMVFRRCTVSGIEYSHDANAQRLAKYQEADSEEEEMVSKVGPISHRGSTGSHQSIWMTHKTQSIKSHRRTGSRAEAKRASMLSKHTAFSSPMEKDITPDPKLLEKVSECDRFLSIAR-HQEHPLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRQKVRVRFELKSPVKTIEDFLRKFTPSRLASG--CSSIGNLTNNKSS-NKSGSTFLPSLSQDNMLLRLEERLGQTAPVIASNGYASQASQAESWTSECTSEQKCPGDQREQQEGELRYEAESPDEAALVYAAKAYNCALVDRLHDQVSVELPHLGR-LTFELLHTLGFDSIRKRMSVVIRHPLTDEINVYTKGADSVVMDLLLPCSSDDARGRHQKKIRSKTQNYLNLYAVEGLRTLCIAKRVLSKEEYACWLQSHIEAETSVESREELLFQSAVRLETNLHLLGATGIEDRLQDGVPETIAKLRQAGLQIWVLTGDKQETAINIAYACKLLDHGEEVITLNADSREACAALLDQCLCYVQSR---NSRSVPQNSESSFSVGFS--FNPASTSTDSS----PSPSLVIDGRSLAYALEKS--LEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRNKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPRFRYLERLLIVHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFYCGFSASAMIDQWYLIFFNLLFSSLPQLVTGVLDKDVPADMLLRKPQLYKSGQNMEEYSPRAFWLNMVDAAFQSLVCFFIPYLAYYDSDVDVFTWGTPVTAIALFTFLLHLGIETKTWTWLNWLACGFSTFLFFSVALIYNTSCATCYPPSNPYWTMPTLLGDPLFYLTCLIAPVAALLPRLFFKALQGSLFPTQLQLGRQLAKK-----------------SLNKFSVPKETFAQGQPPGHTEPELSERKAMGPFESLPRDCASQASQFTQQLACSPEASGEPSAVDTNMPLRENTLLEGLGSQASGSAMPREAIS---EDCPGDSKR---KSTSASQTAPLSSLFHLPSFGSLNWISSLSLASGLGSVLQLSRSSLQMDKQDGEFLSNPPQPDQDLHNLQGQVTGYF----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60312-1", "uniprot_id": "AT10A_HUMAN", "id": "O60312-1", "name": "Phospholipid-transporting ATPase VA", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEREPAG-TEEPGPPG----RRRRR--EGRTRTVRSNLLPPPGAEDPAAGAAKGERRRRRGCA---------------QHLADNRLKTTKYTLLSFLPKNLFEQFHRPANVYFVFIALLNFVPAVNAFQPGLALAPVLFILAITAFRDLWEDYSRHRSDHKINHLGCLVFSREEKKYVNRFWKEIHVGDFVRLRCNEIFPADILLLSSSDPDGLCHIETANLDGETNLKRRQVVRGFSELVSEFNPLTFTSVIECEKPNNDLSRFRGCIIHDNGKKAGLYKENLLLRGCTLRNTDAVVGIVIYAGHETKALLNNSGPRYKRSKLERQMNCDVLWCVLLLVCMSLFSAVGHGLWIWRYQEKKSLFYVPKSDGSSLSPVTAAVYSFLTMIIVLQVLIPISLYVSIEIVKACQVYFINQDMQLYDEETDSQLQCRALNITEDLGQIQYIFSDKTGTLTENKMVFRRCTVSGVEYSHDANAQRLARYQEADSEEEEVVPRGGSVSQRGSIGSHQSVRVVHRTQSTKSHRRTGSRAEAKRASMLSKHTAFSSPMEKDITPDPKLLEKVSECDKSLAVAR-HQEHLLAHLSPELSDVFDFFIALTICNTVVVTSPDQPRTKVRVRFELKSPVKTIEDFLRRFTPSCLTSG--CSSIGSLAANKSS-HKLGSSFPSTPSSDGMLLRLEERLGQPTSAIASNGYSSQADN---WASELAQEQ--------ESERELRYEAESPDEAALVYAARAYNCVLVERLHDQVSVELPHLGR-LTFELLHTLGFDSVRKRMSVVIRHPLTDEINVYTKGADSVVMDLLQPCSSVDARGRHQKKIRSKTQNYLNVYAAEGLRTLCIAKRVLSKEEYACWLQSHLEAESSLENSEELLFQSAIRLETNLHLLGATGIEDRLQDGVPETISKLRQAGLQIWVLTGDKQETAVNIAYACKLLDHDEEVITLNATSQEACAALLDQCLCYVQSR---GLQRAPEKTKGKVSMRFSS-LCPPSTSTASG----RRPSLVIDGRSLAYALEKN--LEDKFLFLAKQCRSVLCCRSTPLQKSMVVKLVRSKLKAMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFAVPKFRYLERLLILHGHWCYSRLANMVLYFFYKNTMFVGLLFWFQFFCGFSASTMIDQWYLIFFNLLFSSLPPLVTGVLDRDVPANVLLTNPQLYKSGQNMEEYRPRTFWFNMADAAFQSLVCFSIPYLAYYDSNVDLFTWGTPIVTIALLTFLLHLGIETKTWTWLNWITCGFSVLLFFTVALIYNASCATCYPPSNPYWTMQALLGDPVFYLTCLMTPVAALLPRLFFRSLQGRVFPTQLQLARQLTRK-----------------SPRRCSAPKETFAQGRLPKDSGTEHSSGRTVK--TSVP---LSQPSWHTQQPVCSLEASGEPSTVDMSMPVREHTLLEGLSAPAPMSSAPGEAVLRSPGGCPEESKV---RAASTGRVTPLSSLFSLPTFSLLNWISSWSLVSRLGSVLQFSRTEQLADGQAG--RGLPVQPHSGRSGLQGPDHRLLIGASSRRSQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T882-1", "uniprot_id": "A0A8N7T882_DANRE", "id": "A0A8N7T882-1", "name": "Phospholipid-transporting ATPase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARETGE-SGETKSGKVKKHKRRKSKKESKTRTVHANILY-----DHTKGGDNPNR-----------------------HYANNKIKTTKYTLLSFLPKNLFEQFHRFANVYFVFIALLNFVPVVNAFQPELALAPVVFILSVTAIKDLWEDYRRHRSDKEINHMDCLVYCRSEKRYVEKYWKELRVGDFIRLRCNEILPADVLLLSTSDPDRLCHIETATLDGETNLKQRQVVRSFIDLDCEFDPLKYNSVIECEKPNNDLNRFRGYIIHRSGRRDGLYKDNLLLRGCTIRNTEEAVGIVIYAGHETKAMLNNNGPRYKRSKLERQMNVDVFWCVIILLVMCLFSAIGHGLWMFQYGDKRPVFDVLGPEGTELSPVVSAIYLFLTMIIVFQVLIPISLFVSIEIVKICQVYFIHQDLELYDEETDSHLQCRALNITEDLGQMQYIFSDKTGTLTENKMVFRRCTVAGVEYSHDANARRIAMYQEVESEEEDCTSHGGTLPRRDSVASHQSGKVVLRSQSTKSHRRTGSRAEAKRASILSKHTAFSSPMEKDITPDPQLMDKVNECSSQMEFMR-FHSQSLNQIPPDLCDVFDFFIALTICNTVVVSSPNQPRQKVR-RFELKSPVKTIEDFIKRFTPSRLTSGSNSSSSSSLATNRSSSHKLGCSMLSSPSAENTLTKLNEEKRQ--EHDLQHAFSPVPPN---FDKSKALAQ---------DECELRFEAESPDEAALVYAARAYKCALVGRLPDQVTVELPHLGK-LSFELLHTLGFDSTRKRMSVVVKHPLTEQITVYTKGADSVIMDLIRPAT-DDCKGKRQRKILYKTQNYLNLYAADGLRTLCIAKKVLSKEEYASWLQRHLEAETAIQRREELLFESALRLETNLQLLGATGIEDRLQDGVPETIASLRKAGLQIWVLTGDKQETAINIAYACKLLDPEEEIITLNADSQEACARLLENSLHYIQAKFLCDPRAGPQAAGDYAGIHFSSPVCSPTSSGHSGPFLVHRLGLVIDGRTLAYALDKS--LEDKFLAVARSCRSVLCCRSTPLQKSMVVKLVRNKLKVMTLAIGDGANDVSMIQVADVGVGISGQEGMQAVMASDFALPRFRYLQKLLLVHGHWCYSRLANMILYFFYKNAMFVALIFWYQFYCGFSGSAMVDQWYLIFFNLMFSAFPQLITGTLDKDVSAETLQELPQLYMNGQNSEEYKPYMFWMNMIDAFYQSLICFFIPYFAYIDSDVDLFTWGTPITTLALFTILLHLGIETKTWTWMNWVSIGFSMALFFTVALCYNASCPTCFSPSNTYWTMQRLLGDPLFYLLCVVTPVAALLPRYCYRACQGTLFPNPVHMGRQLDKLPVEMRRLVLSQSQMKLGSLGSLFAPRAPFFPLCRPFQKDYRPKAKQSHVSSTKPKEKSLASPISSKSVEMRDTPVSSKNSDNHIKLNFRKQDKAQSCR-QASDGPVPENLCYVKEPSSPITGTLPYTKDTPASRTLLESTGLEVPLSPTGLLLSSTPLLSQTETMQLTSPPASCFLGQKLNDEELSNQ-KSLLKQSQDRDHSCLPEHSLKTTFL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KTG6-1", "uniprot_id": "Q7KTG6_DROME", "id": "Q7KTG6-1", "name": "Phospholipid-transporting ATPase", "aln": "MPSANTEDLRRKFLVVQQQRSAPPNLTGDTLSSGIPNASASSATTSLMMTTSTGLGGVAMGAGEPERTYVFPGGNPVVGSAPGGGGQGIPGVAMAAPSRGHARSISHGGGAIVGANGRPIKSAMKGHQRAFSQGQITDSPPGSAAPAGRGHSRVGSKTDFILPPGHKEEPAREPSAPTSATGGRGHSRQASRSESIYTLRRTEAPPWWKRLTLCNYNTGDKFEERSYRTVVPNHTVPPKTPKRDHPNGQFVGNKIRTTKYTLLSFIPKNLLEQFHRVANLYFIFIVLLNWVPEISAFGKEVAMIPVLFVLGVTAVKDLFEDRRRRASDKRINNTTCRVYDGETERYKKVKWQELRVGDIVHLSNNETVPADILLLRTSDPQGVCYIDTCDLDGETNLKRREVVRGFEEMQSIFVPSKFVSRVEADAPTTKLYRFHGALIHPTGERVPISTECLLLRESRLKNTDYIEGIVVYAGHETKSMLNNSGPRYKRSQVEQQMNIDVIWCVIILLILCVVGAIGCRMWLSSFTH----FPVPYLPPNKLTANMESMWIFWTYIVILQVMIPLSLYVTIELCKILQVFHIHNNVDLFDAETNKQTECRAMNITEELGQIQHIFTDKTGTLTENKMIFRRCVVNGSDYNHPP------------SELEKIYSKPGAPAPPLIPNDNLNSDMAQLTQGTYLTPHAQRIQEFLVVLAICNTVIVGAAPHRDMMNASGIIEVQQIGNSPANLKHGKQRQKLLASSTSTTTTTTIINGPTTQPQVVSIPADRYIRLAESRSVTPSPPPNLLFALPAQSHQPTLSP-ISSSAESSPNSESESPSPPMKNKSLSNSISPTGRAKAVINSKITSIATFLNAKTQGKRMKLPSSKTGTIYR------TADGRPLYEAESPDELALVNAAYSYDCCLLNRSPNQILVSMPMAGATREYEILKVLPFDSSRKCMSIVVRQIGSQEIVLYTKGADSSIMPVLVPCSHNSPEG----ILREQTQQLLDRYAREGLRILVMAKRTLNSADYTDWWARHQEIEMSLENRERRLRDSFAKLESNLTLLGATGIEDRLQDGVPETIASLLSAGISVWVLTGDKPETAINIAYSAKLFTQQMELIRLTARSRDAAETAINFYLTDMEND------------KTTSTLGYG-------QSLRKK-----QRALVVDGKTLTFILDPKSKLILPFLRLSKRCASVLCCRSTPLQKAYLVKVVKEELNLRTLAIGDGANDVSMIQMADVGVGISGQEGMQAVMAADFTLPRFRYLERLLLAHGYWCYDRLSRMILYFFYKNAAFVFLIFWYQLYCGFSGQVMMDQMYLMLYNLIFTSLPPLAIGVYDKRVAEDLLLKNPYLYKNGRLGVAYRPHDFWLILLDALYQSLVIFFVALCAYAESDVGIWEFGTTITASCLFANLVHCAIEIRSWTVLHVLSIVLSLGSFYLFAIVYDSVCMNCFGVRSSYWVIFVCFASAVHWLVIMLSTVVAVLPRLLLTTVRISLCP-----------------------------------------------------------------------------------------DDSTKVILQSKRERSRGEALL-------------------------------VTWSRSTSASSIYRITDYGSKNQIITTIT--------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** : . * ** . : * :* : ..*:::*********:****:***** **:**:**.***:** :.** :*: **:*:*.:**.:**:** *: **:.**: * *: . ::* : *:*::***:::* ** .***:*** :***: :*:*:*. ********:*:***.* :: . * * .: * :*.: *...* **:* ::* .*.: : .: **** . ::**: ***:*******::***.*******::*:*** **:***::*: :.:..*:* :*: : . * * ..*:. ::: * * *:::**:**:**:*:**: * **:.*:::::*:* **:.: :***:****:***:::**:***********:****.* * :*.* . ** *. .: *. . .: . :. :*. :: * . :.: . ..:. .:*: . ::: . . . : : : * ... . :: . * ** ..:: .. * ** .: : : . * .** . . ..*. . . . . : . : : .. : : . :******* *** ** :*.* *: * :*: *.:* * :*:*:.* *** ** **:*::: :::* :******* :* :: *.: . .* : :**: *: ** :*** * :**:.*.. :*: * * * * ::: *. * :* :**:** ************:******:.* .**:.:******* ***:****:.**: *:* *.* *::*. :: * :: : :. * .**:**::*:: *: . * ** ::: * ************: :**:*:.:*: ***************:******************:**::*:****::**: **:***.**:.*:*******: ** *:**:*::****...*:** **:::**:*:::* * *. *: *. : * * ** .*: * * **: : ** :***: * :. ** :*:*.:: :**.:.: .*:: *:* .** ::** :: :: :* *: .*: *:: * .*: ..**.: :...:.:* :::.:.*:*** : : : * . * *:. :. .. .: *: :. : : ", "identical_positions": 475, "similar_positions": 402, "identity": "27.24%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101102-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P63079-1", "uniprot_id": "GBRB3_RAT", "id": "P63079-1", "name": "Gamma-aminobutyric acid receptor subunit beta-3", "aln": "-----------------------MWGFAGGR-LFGIFSAPVLV----------AVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAY------------SGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRS-KSEINR---------------------------VDAHGNILLAPMDVHNEMN--EVAGSVGDTRNS-AISFDNSGIQYRKQSMPKEGHGRYMGD--RSIPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P63080-1", "uniprot_id": "GBRB3_MOUSE", "id": "P63080-1", "name": "Gamma-aminobutyric acid receptor subunit beta-3", "aln": "-----------------------MWGFAGGR-LFGIFSAPVLV----------AVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAY------------SGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRS-KSEINR---------------------------VDAHGNILLAPMDVHNEMN--EVAGSVGDTRNS-AISFDNSGIQYRKQSMPKEGHGRYMGD--RSIPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P28472-1", "uniprot_id": "GBRB3_HUMAN", "id": "P28472-1", "name": "Gamma-aminobutyric acid receptor subunit beta-3", "aln": "-----------------------MWGLAGGR-LFGIFSAPVLV----------AVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAY------------SGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRS-KSESNR---------------------------VDAHGNILLTSLEVHNEMN--EVSGGIGDTRNS-AISFDNSGIQYRKQSMPREGHGRFLGD--RSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BDH7-1", "uniprot_id": "A0A8M2BDH7_DANRE", "id": "A0A8M2BDH7-1", "name": "", "aln": "MRLAGWDSLRAENMRLWWILLLSFWSVYGELPFIAENNAAMLVNWNAVDGNKKLFAIYDTSANEPGNMSFVKETVDKLLKGYDIRLRPDFGGAPVAVGMSIDVASIDMVSEVNMDYTLTMYFQQYWRDKRLAY------------TGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWKGGETAVTGVSRIELPQFSIVDYKLVSRNVVFSTGAYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQMQKKLAEKAEKANNDRN-KYDGNKSVQEGGNCKPSSVKQSNQVQGHRHSRGVDSQGNILLTTLEIHNEVAGNEITTSVSEARNSTSMVFDNSGIQYRKQST-----ARHSMD--RNAQSKKPRLRRRSSQLKIKIPDLTDVNAIDRWSRIIFPAVFSLFNLIYWLYYVN-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q08832-1", "uniprot_id": "GBRB3_DROME", "id": "Q08832-1", "name": "Gamma-aminobutyric acid receptor subunit beta-like", "aln": "------------------MTCFTRVGVSCGLFFFLLGAQLQLIR-------------CIRKDVLAGRLENVTQTISNILQGYDIRLRPNFGGEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAFNIFGQYFDDENDDGISDVLTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYGMRFTTTLACMMDLHYYPLDSQNCTVEIESYGYTVSDVVMYWKP--TPVRGVEDAELPQFTIIGYETNDRKERLATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTVLTMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNYTYWGKRAKKKIKKVKECCPGKIGKSERSETCS-----------------------TTEDIIELQDVRMSPIPSLRRGTYNATLDSIGTETMN-LGKFPPSFRITRNYGTGHSQLRRRAQRGISTRPRMLHALKRGASAIKATIPKIKDVNIIDKYSRMIFPISFLAFNLGYWLFYILE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :: *: . .*.:. *.:*:.::*:********:*** *: ***.: :**:* :********:***::*****:***: **. ***.. .*:::*****:* ***:**:*.** :*:::** **:* **:*:*** ******: ****.****:********..*: :**: ..* **. *****:*: :. .*: ::**.* ******:*:******::***:*****.:*********::*::****************.* :*.:**:*.******:**: ****** ****** *** ::*: .: : * .:: .: .:. : : : :: ::.: .. .:. . * * *: . * . *:* :* :* .**.:.*** **::**::** * *** ***:*: ", "identical_positions": 216, "similar_positions": 131, "identity": "39.06%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101102-9", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9DCD6-1", "uniprot_id": "GBRAP_MOUSE", "id": "Q9DCD6-1", "name": "Gamma-aminobutyric acid receptor-associated protein", "aln": "MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQFYFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95166-1", "uniprot_id": "GBRAP_HUMAN", "id": "O95166-1", "name": "Gamma-aminobutyric acid receptor-associated protein", "aln": "MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQFYFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A890-1", "uniprot_id": "A0AB13A890_DANRE", "id": "A0AB13A890-1", "name": "", "aln": "MKFQYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQFYFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** **************************************************************************************************************** ", "identical_positions": 115, "similar_positions": 0, "identity": "98.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101103-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P21139-1", "uniprot_id": "MA2C1_RAT", "id": "P21139-1", "name": "Alpha-mannosidase 2C1", "aln": "-----MAAAPFLKHWRTTFER----------------VEKFVSPIYFTDCNLRGRLFGDSCPVT-LSSFLTPERLPYEKAVQQN-------FSPAQVGDSFGPTWWTCWFRVELVIPEVWV--GKEVHLCWESDGESLVWRDGEPVQGLTKEG-EKTSYVLSERLHAADPR----------SLTLYVEVACNGLLGAGKGSMIAAPDPEKMFQLSQAKLAVFHRDVHNLLVDLELLLGVAKGLGEDNQRSFQALYTANQMVNICDPAQPETYPAAEALAS-----------KFFGQRGGESQHTIHATGHCHIDTAWLWPFKETVRKCARSWSTAVKLMERNTEFTFACSQAQQLEWVKNQYPGLYAQLQEFACR-GQFVPVGGTWVEMDGNLPSGEAMVRQFLQGQNFFLQEFGKMCSEFWLPDTFGYSAQLPQIMQGCGIKRFLTQKLSWNLVNSFPHHTFFWEGLDGSQVLVHFPPGDSYGMQGSVEEVLKTVTNNRDKGRTNHSGFLFGFGDGGGGPTQTMLDRLKRLGNTDG-----QPRVQLSS-PGQLFTALERDSGQ---LCTWVGELFLELHNGTYTTHAQLKKGNRECEQILHDVELLSSLALARS-AQFLYPAVQLQRLWRLLLLNQFHDVVTGSCIQLVAEDAMNYYEDIRSHGNTLLSAAAAALCAGEPGPKGLRHYQHTALEAHRSVGTTQGLVGLTRLALVTVPSIGYAPAPTPTSLQPLLPQQPVFVMQETDGSVTLDNGIIRVRLDPTGCLTSLVLVASGREAIAEGALGNQFVLFDDVPLYWDAWDVMDYHLETRKPVRGQAGTLAVGAEGGLRGSAWFLLQISPNSRLSQEVVLDVGCP-------YVRFHTEVHWHETHKFLKVEFPARVRSPQATYEIQFGHLQEADPQQHSWDWARYEVWAHRWIDLSECDFGLALLNNCKYGTSVRGNVLSLSLLRAPKAPDVTADMGRHEFTYALMPHKGSFQEAGVIQAAYNLNFPLLALPAPGPAPDTTWSAFSVSSPAVVLETIKQAEKS-----------HQHRTLVLRLYEAHGSHVDCWLHTSLPVQEATLCDLLEQRDPTGHLSLQD------NRLKLTFSPFQVRSLLLVLQPPAN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91W89-1", "uniprot_id": "MA2C1_MOUSE", "id": "Q91W89-1", "name": "Alpha-mannosidase 2C1", "aln": "-----MAAAPFLKHWRTTFER----------------VEKFVSPIYFTDCNLRGRLFGDSCSVT-LSSFLTPERLPYEKAVQQN-------FSPAQVGDSFGPTWWTCWFRVELVIPEVWV--GQEVHLCWESDGESLVWRDGEPVQGLTKEG-EKTSYVLSERLRASDPR----------SLTLYVEVACNGLLGAGKGSMIAAPDPEKMFQLSQAKLAVFHRDVHSLLVDLELLLGVAKGLGEDSQRSFQALHTANQMVNICDPAQPETYPAAKALAS-----------KFFGQHGGESQHTIHAMGHCHIDTAWLWPFKETVRKCARSWSTAVTLMEQNTDFIFACSQAQQLEWVKSQYPGLHARLQEFACR-GQFVPVGGTWVEMDGNLPSGEAMVRQFLQGQNFFLQEFGKMCSEFWLPDTFGYSAQLPQIMQGCGIKRFLTQKLSWNLVNSFPHHTFFWEGLDGSRVLVHFPPGDSYGMQGSVEEVLKTVTNNRDKGRTNHSGFLFGFGDGGGGPTQTMLDRLKRLSNTDG-----LPRVQLSS-PGQLFTALERDSGQ---LCTWVGELFLELHNGTYTTHAQLKKGNRECEQILHDVEVLSSLALARS-AQFLYPAAQLQHLWRLLLLNQFHDVVTGSCIQLVAEDAMNYYEDIRSHGNPLLSAAAAALCAGEPGPKGLLIINTLPWKRTEVLALPK-PCGAHSLALVTVPSIGYAPAPTPTSLQPLLPQQPVFVMQETDGSVTLDNGIIRVRLDPTGCLTSLVLVASGREAIAEGALGNQFVLFDDVPLYWDAWDVMDYHLETRKPVLGQAGTLAVGTEGGLRGSAWFLLQISPNSRLSQEVVLDVGCP-------YVRFHTEVHWHEAHKFLKVEFPARIRSPQATYEIQFGHLQRPTHNNTSWDWARYEVWAHRWIDLSECDFGLALLNNCKYGASVRGNVLSLSLLRAPKAPDATADMGRHEFTYALMPHKGSFQEAGVIHAAYNLNFPLLALPAPGPAPDTTWSAFSVSSPAVVLETIKQAERC-----------HQHRTLVLRLYEAHGSHVDCWLHTSLPVQEATLCDLLEQRDPTGHLSLQD------NRLKLTFSPFQVRSLLLVLQSPPN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NTJ4-1", "uniprot_id": "MA2C1_HUMAN", "id": "Q9NTJ4-1", "name": "Alpha-mannosidase 2C1", "aln": "-----MAAAPALKHWRTTLER----------------VEKFVSPLYFTDCNLRGRLFGASCPVAVLSSFLTPERLPYQEAVQRD-------FRPAQVGDSFGPTWWTCWFRVELTIPEAWV--GQEVHLCWESDGEGLVWRDGEPVQGLTKEG-EKTSYVLTDRLGERDPR----------SLTLYVEVACNGLLGAGKGSMIAAPDPEKMFQLSRAELAVFHRDVHMLLVDLELLLGIAKGLGKDNQRSFQALYTANQMVNVCDPAQPETFPVAQALAS-----------RFFGQHGGESQHTIHATGHCHIDTAWLWPFKETVRKCARSWVTALQLMERNPEFIFACSQAQQLEWVKSRYPGLYSRIQEFACR-GQFVPVGGTWVEMDGNLPSGEAMVRQFLQGQNFFLQEFGKMCSEFWLPDTFGYSAQLPQIMHGCGIRRFLTQKLSWNLVNSFPHHTFFWEGLDGSRVLVHFPPGDSYGMQGSVEEVLKTVANNRDKGRANHSAFLFGFGDGGGGPTQTMLDRLKRLSNTDG-----LPRVQLSS-PRQLFSALESDSEQ---LCTWVGELFLELHNGTYTTHAQIKKGNRECERILHDVELLSSLALARS-AQFLYPAAQLQHLWRLLLLNQFHDVVTGSCIQMVAEEAMCHYEDIRSHGNTLLSAAAAALCAGEPGPEGLLIVNTLPWKRIEVMALPK-PGGAHSLALVTVPSMGYAPVPPPTSLQPLLPQQPVFVVQETDGSVTLDNGIIRVKLDPTGRLTSLVLVASGREAIAEGAVGNQFVLFDDVPLYWDAWDVMDYHLETRKPVLGQAGTLAVGTEGGLRGSAWFLLQISPNSRLSQEVVLDVGCP-------YVRFHTEVHWHEAHKFLKVEFPARVRSSQATYEIQFGHLQRPTHYNTSWDWARFEVWAHRWMDLSEHGFGLALLNDCKYGASVRGSILSLSLLRAPKAPDATADTGRHEFTYALMPHKGSFQDAGVIQAAYSLNFPLLALPAPSPAPATSWSAFSVSSPAVVLETVKQAESS-----------PQRRSLVLRLYEAHGSHVDCWLHLSLPVQEAILCDLLERPDPAGHLTLRD------NRLKLTFSPFQVLSLLLVLQPPPH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B7A6-1", "uniprot_id": "A0A8M3B7A6_DANRE", "id": "A0A8M3B7A6-1", "name": "Alpha-mannosidase 2C1", "aln": "-----MYHQPVLKNRRTLLER----------------VEKFISDIYFTDCNLRGRLFGDIYPLESISVFLSEKRIPYSEAIQQN-------FQPCKVGDSFGPTWWTCWFKVNLKIPETWG--GKEVHLRWESDGEGMVWQNQQPVQGLTNEG-EKTSYILTECLKDSESHGLVEICSIDKIITLYVELACNGLFGAGQGSMIAAPDPNRKFTLQKAELVVFNRDVMELLTDFEMLLDMVKVLGEGEQRGFQALFTANEMVNLCDPANPGSFAAARSLAQ-----------KFFAQKNGESQHVVHAMGHCHIDSAWLWPYEETIRKCARSWVTVIRLMEKNPEFVFTCSQAQQFQWVKSWYPGLFSEIKHFIQK-GQFIPVGGTWVEMDGNLPSGESMVRQFLHGQNFFKDEFGNYCKEFWLPDTFGYSAQLPQIMKGCGISRFITQKLSWNLINTFPHNTFFWEGIDGTAVLTHFPPGNSYEMKGKVEDLINTVKNNKDKGRANHSALLFGFGDGGGGPTQLMLDRLHRVKDTDC-----LPKVQMST-PDVLFSHLESDSSL---LCRWVGELFLELHNGTYTTQAKIKMKNRQCETLLHDVEVASCLALSKK-DSFKYPACRLQELWRLLLLNQFHDVIPGSCIGMVVEDALQYYDEIHTTASRLLLDACKSLPSSPD--NGIAVLNTLSWERTEVISLPM-KDTETRLALVRVPSVGVAHVK-----ETAESAESVIATMMVNGTIIMENGLLKATIDHLGRLMSLLLIQTNRETISEGCFGNQFALFDDVPLYWDAWDVMDYHLQTRKPVIEVIEPAKVLKSGGIQASVSFSLRINGKSTIQQEIVLDACCP-------YIKFKTHVVWEEAHKFLKVEFPVQVRSPEATYEIQFGHLQRPTHRNTSWDWARFEVWGHKWADLSEHGFGVALLNDSKYGYSVHQNIMTLSLLRAPKAPDLNADMGDHIFSYALMPHTGTFQESAVIQYAYNFNYPLRVHHGVIPKP---WSAFSVSSPAIILETIKKAEK-------------RENALLIRLYESHGSRVTVTLSTSFLLQEVWHCDLLERPDFRIPVSETT------SGISLTFKPFQIRSLLLIIQ----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P22855-1", "uniprot_id": "MAN1_YEAST", "id": "P22855-1", "name": "Alpha-mannosidase", "aln": "MSSEDIIYDPQFKPVQGIYENRLRQFIDTGGDYHDLNLPKFYDKKRISLDHDHVKVWWYQVSFERGSSPVSPDKRPSWKSIIERDKKGELEFREANINQPFGPSWSTTWFKVKISLPEDWVKSNEQLLFQWDCSNEGIVIDPKTLIPVTAFSGGERTEYVLPKTSDG--------------KHFFYIEAGNNGMFGCGAGSTINPPDDNRFFHLRKADIVWPDLDARALYIDFWMLGDAARELPGDSWQKHQARQLGNAVMNLFDPNDRSSVRKCRELLQREYFDSFLESSKVYEQGESQVLTNVYGIGNCHIDTAWLWPFAETRRKIVRSWSSQCTLMDRFPEYKFVASQAQQFKWLLEDHPEFFNKVLIPKIQQSQFFAVGGTWVENDTNIPSGESLARQFFFGQRFFLKHFGLKSKIFWLPDTFGYSSQMPQLCRLSGIDKFLTQKLSWNNINSFPHSTFNWAGIDGSQLLTHMPPGNTYTADSHFGDVLRTAKQNKTPEYYGSGLMLYGKGDGGGGPTEEMLQKMRRIRSMNNRNGNVIPKLQVGITVDEFYDDILKRTNQGHDLPTWSGELYFEFHRGTYTSQAQTKKLMRLSEIKLHDLEWIAAKTSVLYPDSYKYPSKQINELWENVLLCQFHDVLPGSCIEMVYKYEAVPMLHNVVKECTSLIDKTVQFLQSQS-KADLVEMRTLTWSKPEKVSEECSLNGSYTSSVTGYDDY------------------IVLANGKLKVIICKKTGVITSITDET-----LGVEYLDTEHGRNKLGANQFVIYDDKPLGWQAWDTELYSVNQYKYVTKPK-KVQVSCNTKEKCAVEVIFQISEKCKIKSVISLNATAVTDAKLSKVDISTTVENWDARNKFLKVEFPVNIRNDFASYETQFGITKRPTHYNTSWDVAKFEVCHHKFADYSEYSKGVSILNDCKYGFSTHGNLMRLSLLRSPKAPDAHADMGTHEIKYAIYPHRG-ALSSDTVKLAHEFNYCFKYKLPKDIGMNFDDIISISGDENVILSNIKRGEDDSAVKSNYSLNPRDEQSIVVRVYESLGGESFASLNTTLNLKRIEKVDNLEMKVYKSLTATRDESNHAINRIPIKLRPFEIASFRLYF-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :* : *. : ** . :: : : ::: .. * :: .: * ::: . * .::.:.***:* * **:*:: :** * .::: : *:...*.:* : : .* *:*.*:*.. :*:* . **::*.* ** * .** :: * * :*.:. . *. * *: :* . .: * .. : .** .* ::*: ** : : .. * . :.: * .: ::. *:****:*****: ** ** .*** : **:: .:: *..*****::*: . :* :. .: : .**..******* * *:****::.***: **.** ..** .. **********:*:**: : .** :*:******* :*:*** ** * *:**: :*.*:***::* .. . :::.*. :*: . . :*:* ********: **::::*: . : *::*:. :: : : * * ***::*:*.****::*: * * .* ***:* :. : .: **: :::.**. :** *****:.**** :* : . * : . .: . . . . :. ::. . *:. . : ..*:: * * : . * : .***.::** ** *:***. * :: * * * . : :. . ::*. :. :.. : *:. . * *. :********..:*. *:** *** :.. : *** *::** *:: * ** . *:::**:.*** *.: .:: *****:***** ** * * :.**: ** * .: .:: *:.:*: : .. ::*..:*:.* ..::::*:**: *.. * :: ::. * ** : . : :.: **:: *: * : ", "identical_positions": 289, "similar_positions": 325, "identity": "25.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101104-10", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6NGG8-1", "uniprot_id": "PCARE_HUMAN", "id": "A6NGG8-1", "name": "Photoreceptor cilium actin regulator", "aln": "MGCTPSHSDLVNSVAKSGIQFLKKPKAIRPGCQGGSERGSIPLLVKNSTCYDAGEGLAEEQPSPRRNQTTAKGLCQLMGDPASGKRKDMEGLIPGTKTSSSQLNKSQSHMAKDIPFKTQGSHGSQGADFSGDESEESSTQDTSKWKRTAKCHTSSTQSHCYQTIHPAHEPEGKVDFPEPLVKAHQQAYTYLHSSLSKYEAILCIIHQATQTRELLQPMVSFLLLCFEEISQLLGEISKDGEVLLQEVREDLAWPLKKREP------------QEQ-PNLLQQLLQYTVSKLQVLNGTVASLTGSFLEGSSSYLHSTATHLENKLSTKRNVDERLLRALRQLESLASGCGDPGVQGLPLCSEDSGIGADNESVQSVDKLGKQTSWDLAPEPEEWKSVTSPHTEARQSGHTWQQSPFCLGSGRPQDCLLSGAPMAKVQPRAQDEARSPCLSSTSPENITSPPLKLGTSTPCDSFGIGVSVEPHLSKTSRPMDASSLSDSEDSSPEEEEEDKMSSMSLCAWQEKTPHSRPQSSPADRESPFQARTRRLRSLQAQEMILKMKESISERIKFVPVPCGHQDWSEEEEGRTVVPPRPSTVSGSRRAPERQTRSQSESCLQSHVEDPTFQELRRVQRDLSQKLEAFYALGAKGQGQ--SQEQILQPRAAAVWPNGTCRVSPSNTTSRLKASLTKNFSILPSQDKSILQKCNPHPEDEQ---GKAGKLPNAIPSGEVS-EAAKATDWNVRGCP-TRTSVKKLIETFSP--TESLRMLGDSKDAGASPCLRNC---IMPPRFPKYTGLAPLYPKPQISPASGRESLKMGIGWKPLAPIFPPLPKAEAAKSEELSCEMEGNLEHLPPPPMEVLMDKSFASLESPESSKSTENSPKETQEPGPGEAGPTRRTWASPKLRASVSPLDLLPSKSTASLTKPHSTGPGSGRSSCQPRKPALDLSSPPATSQSPEVKG--GTWSQAEKATSLYRQPRKAIAWHHSGPPSGQNRTSESSLARP----------RQSRERSPPVGRKASPTRTHWVPQADKRRRSLPSSYRPAQPSPSAVQTPPSPPVSPRVLSPPTTKRRTSPPHQPKLPNPPPESAPAQCKVPSPPTQHPEASPPFSIPSPSPPMSPSQEHKETRD---SEDSQAVIAKVSGNTHSIFCPATSSLFEAKPPLSTAHPLTPPSLPPEAGGPLGNPAECWKNSSGPWLRADSQRRAALCALNPLPFLRRTASDRQPGGRPQPPTLDPTSTSYESQLGQNSSS----EESPKKDTEPGSSPCSPELQGG-TRRASPPEFCVLGHGLQPEPRTGHIQDKSQPEAQPQQEEVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PAC4-1", "uniprot_id": "PCARE_MOUSE", "id": "Q6PAC4-1", "name": "Photoreceptor cilium actin regulator", "aln": "MGCTPSHNVIVNSVAKSGIQFFKKPKAILPGCQWGSPKCPIPLLVQSSTFCDSGGELHLGERLVEETVSSSK-KLQAMAEGVRQLPKAMEGLIP--ESQTFQVNKPQGHRATDISFRTEGSHGTQEVDFSGKESKENTPQETSKGNRESVCHQPDSQDHCRQS---ATESKGRVDFPEPLVKAHQHAYAYLHTSLSRYEAIVRLVQQASQTWGLLRPMLNFLLLCFEEAGQLLSEISKDGDVLLQEVRGDLAWPLRKGEP------------WEQHPDLLQQLLQYTVSKLRALHGTVAALTGSFLEGSSSCLRSTAGHLEGKLSTKRGIDECLLRALGQLESLTSSHGDAGLLGPPLCSEDSGIGADNESVHSVEKLGKQASWDFAAELGEWKPGTAAQVEARPSGHAWQEGPYWTGSDRPQDCPLSSPRIAKVQPAVQDEARSASTSGAGAEAVTSGPSEAAESLPWDSLGAEIPVRTPLSRSSGLTDAPSLSEEEDCSPEEEDE--LSSTDLHPEPQKALPSRPRSSPDTRESLFQPYSKELRNPQAQEMILKMKEAISERIKFVPEPSRPQDWTEEEEGGTVVPPRPRSVSGSRGGPERQRRSQSEGCLKSHVEDPTLQELRRVQTDLSRRLEVFYALGATRQGQ--SRERCLPSRASVLWPPTNCRVSPSSAISKFKASLTQNFSILPNQDKSIFQKGSPCFDGEQPCQGKAEKLPNAIFCGKKSGRAPRDNERDIRACP-TRPSVKTLIETFSP--TESLRMPRNCRNLGSSPCLRKWGVPAMPPRFPIYRGLAPLYSKPQISPAAG---------WRPSAP-FPSLPLAEVSESEDISGDVEEDLENLPPPPLEVLMDKSFAALECPECSQPAGSSLEETLLPGLQEASHPKRTWVSPRLKASMSPMDLLPSKGSGSSPRLHSTRSGSTRIVGDSRKLTLDLNSKQTASPSSEAKSRAQIQARAETIAGFSKQHQKAIPWHHTNPTPGQSRTLEPSLARFSRDPHSSEASRKGPERSLPRVRKASPQRAQWASQGDRRLQSLPSSHGPSQPGLPAVLSSPSPPLSPRTLSPPATRKTTSPPCQHPQSNPAPG---------SPPVRRTETNTPSSASCSSPSVSPSRGSKDSIH---SEDSEATTAKASRNTCSIFYPAATSLFEAKSSSSTSH----PQMLPEPGGLLRTPTGGWRGSSGQRLRADSQKRTVLNALNPLPFVRRTASDRQ---RQQGDQLQQSRSDWEFHSCQNSSSSSSSEENPKQELPPWNNSRVPELQGSSTKRASPLELCVLGHGLQPEARMNRGQDRPQPESQPQHKEIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2KDL6-1", "uniprot_id": "A0A0G2KDL6_DANRE", "id": "A0A0G2KDL6-1", "name": "", "aln": "MGCSPSR-----------------GRTLLP----GTHESPGETQSHNGSIGDSERGNSTARPYERKFSTAECEADGAASAKLSTQEININ----------------------------ILSQAKEKQEEKREDCEKKGGKKSKKSTKSVRVNKRKEKE--------IKLVQEKVDFPEELVKAHQAAYGYLNPSITKYEDLLGLLDHAAQTQISLQPMVAFMVLRYEEINKGLQEIVEEGEAMFKGNGEHLAWPCEKNKSSYNAKNATTSTCSDPPPDLLQQLLQYTVQRMRQVGQSVCGIGDTALEEAVEYFSSITDILDEKLRAKRASESRLMWLLSRIEAASQ--KKPSPEDSALFSEDSGLGAESESLAGSDRQRQRRESSES-------SGTICATISSPCGFTPIQRGSYRG--RLLKTMSSSSSLNSLDSTCTITAKDKKDTDS------------------------------LLGSVSLDEGDFTNGSEKVKWNEKRSKQSEASTSELRQPRRLPAKRIENPQN-----VEMTLKLKDAISGRIRFLPTQGPGEKAKQTESPKSSSQQWAEDGDKSSKRPQTAASRTSKKKTTVTKRSRSADSLRNKAEDPTLIELERTQKELNQKLERMTKVKGEGNKRQCSSKKFLPCQTQNISSVTDRQRS---LTRNIFSPSNQRKACNAKVEQATTQNGTEKMDNEKGKEKDKKAPPVKGSVKIIPVPSPPPSPRQSSGLYRERNSVQKLIDTFSQGLEESKQVPESVKILGPLKGVRKCG-------VPIIPGLGPSGTSAFID----------------------NSILCGQGESQCSERTDDLDIDNLPPPPLEVIMDNSFENVQTNAKSENISR----------GRSTLTKKTAMSQKLRASLLSVTVLPSRGN------LCKGPVSMSQVCSTQNDTREVVKGAHHDSSHETDT------ESEEAASLYKQSRKIIHLRHSSDSPMEKNTSEQDNRQLS-----------SSCRSDVGEQKDNSTNETMPNSACRSQNPLTSPISRTRVLPSTPLLHRRLPSPPVLKSQPSSSTSSSPPINRKLPSTPSAG---QRTLPSTPLMQQEHTPITMTGVTYPFKAPSPPASPKVQRWSRENSTEDTSRVFSNARSVFCPASSSLFEAQSVPTPKP----PQAWTSTGSNVLPRPWGERG------------RLPVSARGPQPFIRRSQSDRRP--SLSMSSRVPVISVAETCGSEPAICTHGLEEGPVREDKIRSEQ---TEIRSAVRSVSHPDLCIVGQGLQREWEK-------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:**: ::: * *: . . :..: *: . .. :: . :: *:..: : . .:.::. :.:.* .: : . :. : :***** ****** ** **:.*:::** :: ::.:*:** *:**: *::* :** .: * ** ::*:.::: .**** .* :. : *:**********.::: : :*..: .: ** : . : * : *: ** :** :. *: * ::*: :. ... . .* *****:**:.**: . :: :: . . : . * . : .*.: : * * . *.. : .::. *:. :.: * : :. . .*. . :*: . .: : :: ..* : .*:. : .: : .:. .*: * . * .: *: . : *:. : *: . **:* ..*:.:.****: **.*.* :*.::** : : . : : * :: * :: : . : * .: :. .:. : .. ::: *: . :.*: . * . :. . : . * **:.**:*** ** :: . : *. :*: .* **.* ... *. . .:*: . : ::::*****:**:**:** :: *: .: .::* * :*:**: .: :***:.. .. . * ..:: : :: . . * *.. .:* :.: :* :* * :*:. .. :..* * . : . ** :* .. . .. : ..*.*. :: .: * .* * *:: :*** : ..... *.* : * .. . * :** . . . *:* ::. *: *:* **::*****:. :. *. ...*. : . :. * : * .* **:**: ***: . : * : : . **.* :: .. . .: .* ::*::*:*** * . ", "identical_positions": 219, "similar_positions": 389, "identity": "16.43%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101104-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35714-1", "uniprot_id": "TNR18_MOUSE", "id": "O35714-1", "name": "Tumor necrosis factor receptor superfamily member 18", "aln": "------MGAWAMLYGVSMLC-----VLDLGQPSVVEEPGCGPGKVQNGSGNNTRCCSLYA-------PGKED--CPKERCICVTPEYHCGDPQCKICKHYPCQPGQRVESQGDIVFGFRCVACAMGTFSAGRDGHCRLWTNCSQFGFLTMFPGNKTHNAVCIPEPLPTEQYG---------HLTVIFLVMAACIFFLTTVQLGLHIWQLRRQHMCPRETQPFAEVQLSAEDACSFQFPEEERGEQ-TEEKCHLGGRWP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y5U5-1", "uniprot_id": "TNR18_HUMAN", "id": "Q9Y5U5-1", "name": "Tumor necrosis factor receptor superfamily member 18", "aln": "MAQHGAMGAFRALCGLALLC-----ALSLGQ-RPTGGPGCGPGRLLLGTGTDARCCRVHTTRCCRDYPGEEC--CSEWDCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEGHCKPWTDCTQFGFLTVFPGNKTHNAVCVPGSPPAEPLG---------WLTVVLLAVAACVLLLTSAQLGLHIWQLRSQCMWPRETQLLLEVPPSTEDARSCQFPEEERGERSAEEKGRLGDLWV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5N2-1", "uniprot_id": "A0ACD6B5N2_DANRE", "id": "A0ACD6B5N2-1", "name": "", "aln": "MHHSDRMNTVKLWVTLLCVCGRGILSLDCDWTTEYDDNNRCCKACPAGEYPISACSQDRTDSLCEKCPSDLTHLSAENRCFCKDKHLCAGYQCEDCQPREKCKPGQQLMRIGNFHFSFYCAPCQNNTYNDVEDSTCKPITKCDGVG--EFFPGNQTHNANCVPEEVIPDTTKSPPEQNRSQYFQSLMVACITITVLTCLVFITLSAFQIFKYKTFIKLNRSKLCTHTRVVSSESCKLSKEERGESDHEHKIDLSEDCDHSFP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.: : :* *. . . * : *. : *.. ..: *:* . .* : * *** : *.: *.* * * .*:. .:. *: *.* .* .****:**** *:* .: : :::. : .: . : * :*: : .: . . .: * ::.:***** *.* *. ", "identical_positions": 44, "similar_positions": 62, "identity": "16.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101105-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O15209-1", "uniprot_id": "ZBT22_HUMAN", "id": "O15209-1", "name": "Zinc finger and BTB domain-containing protein 22", "aln": "MEPSPLSPSGAALPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTELLREGR-ASATTTITTAAATSVTVPGAGVPSGSGGTVAPATMGSARSHASSRASENQSPSSSNYFSPRESTDFSSSSQEAFAASAVGSGERRGGGPVFPAPVVGSGGATSGKLLLEADELCDDGGDGRGAVVPGAGLRRPTYTPPSIMPQKHWVYVKRGGNCPAPTPLVPQDPDLEEEEEEEDLVLTCEDDEDEELGGSSRVPVGGGPEATLSISDVRTLSEPPDKGEEQVNFCESSNDFGPYEGGGPVAGLDDSGGPTPSSYAPSHPPRPLLPLDMQGNQILVFPSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGTGSGDGNKIFLCHCGKAFSHKSMRDRHVNM-HLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRHRGHCERRHRLG------GVGAVPGPGTPTGPSLPSKRESPGVGGGSGDEASAATPPSSRRVWSPPRVHKVEMGFGGGGGAN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z0G7-1", "uniprot_id": "ZBT22_MOUSE", "id": "Q9Z0G7-1", "name": "Zinc finger and BTB domain-containing protein 22", "aln": "MEPSALSPSGATLPLPLSLAPPPLPLPAAAVVHVSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFHDQVLLKGMTSISLPSVMDPGAFETVLASAYTGRLSMAAADIVNFLTVGSVLQMWHIVDKCTELLREGRSAATTTTVTTAAAPSVSVPCASVPSGNGGTVAPATVGSVRSHTSSRASENQSPSSSNYFSPRESTDFSSTSQDAFVASAAGSGNRRDGGPVFPAPVVGSAGTTSGKLLLEADELCDDGGDGRGAVAPGAGLRRSNCMPASAVPQKHWVYVKQARNCPAPASLVHQDPDLEDEEEEEDLVLTCEDDEDEEMGGGSGVPAGGEPEATLSISDVRTLTEPADKGEEQVNFCESSNDFGPYEGGGAGAGLDDPGGPTPSSYALTHPPRPLLPLDVPGNQILVFPS----SSSQAPGQPPGNTAEHGAVTLGGTSAVGLGIPSGSGGAPGGTGNSDGNKIFLCHCGKAFSHKSMRDRHVNM-HLNLRPFDCPVCNKKFKMKHHLTEHMKTHTGLKPYECSVCAKKFMWRDSFMRHRGHCERRHRMGVGGVGSGPGPGPGPGTPSGPALQPKRESSTVGGGSGDEANSATPPSHRRVWSPPSVHKVEMDFSGGGGAAH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QFB7-1", "uniprot_id": "F1QFB7_DANRE", "id": "F1QFB7-1", "name": "", "aln": "MEQMFGRSS----------APP------GPVLQVCFPSARASVLENLNRQREEGQLCDLSIQVQGQVFRAHRCVLAASSPYFHDQVLLKNVTTVSLPSVMDPLAFESVLNSAYTGQLSIVRDDIINYVTVASFLQMWHIVDKCTDILKRSR------------------PLAQISPGG---------------ATSSSHQSPSSSDCCFADPEDATTEQTLEKRPHSALPPLATWRR--------PQQNRWSRSTLTFPLRPDSECGSNAAGVHGCS-AAPLPSLVSPPELDFAARHRIRVRLRGAKEEEEQRRMEADEGVGEPSQEDRVRVK--NEEHQAG-------VAEPDGSLRESESRESLQETDGLWQSVTEWP-LDDKVLDEDDKTDLSFETYDEIEKATGQISQ--RPLLPSELS------WVS---QSSSSSPCSP-----------LSATP-----------------------KVHFCHCGKAYTLKSMRDRHVKMQHLNLRPFSCPVCSKSFKMKHHLTKHVKTHGGLRPYECSVCGKKIVWRDSFLKHQARCQR--------------------TP---------ETSAESGGQQEDADGAG--QVKVEQDDYSLQEEEMHS--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .* *** ..*::*.**.. :::**.**:** :*****:**:***: *****.****************.:*::******** ***:** *****:**:. **:*::**.*.***********::*:..* * * :..*. ::* : :. *.*.. : .*.::* .: .: .. * . : ** * . . :: .: *..*. *.... * . .* * * .. :* : *: : : * .:** * . :*:.: * . *:.:* *: * : .* :.*. :* *.. . .:: . :: :: ***** :: : * ***.:* .* :..*. *:.:******:: ********:* *******.****.*.********:*:*** **:****.**.**::*****::*:.:*:* ** *:. .**. ::*..* . : . ::: ** ", "identical_positions": 201, "similar_positions": 158, "identity": "31.26%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101107-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NZ56-1", "uniprot_id": "FMN2_HUMAN", "id": "Q9NZ56-1", "name": "Formin-2", "aln": "-MGNQDGKLKRSAGDALHEGGGGAEDALGPRDVEATKKGSGGKKALGKHGKGGGGGGGGGESGKKKSKSDSRASVFSNLRIRKNLSKGKGAGGSREDVLDSQALQTGELDSAHSLLTKTPDLSLSADEAGLSDTECADPFEVTGPGGPGPAEARVGGRPIAEDVETAAGAQDGQRTSSGSDTDIYSFHSATEQEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGAPVRGAGDTDEEGEEDAFEDAPRGSPGEEWAPEVG----EDAPQRLGEEPEEEAQGPDAPAAASLPGSPAPSQRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKRRPEPSLSRGSRTALASVAAPAKKHRADGGLAAGLSRSADWTEELGARTPRVGGSAHLLERGVAS------DSGGGVSPALAAKASGAPAAADGFQNVFTG-RTLLEKLFSQQENGPPEEAEKFCSRIIAMGLLLPFSDCFREPCNQNAQTNAASFDQDQLYTWAAVSQPTHSLDYSEGQFPRRVPSMGPPSKPPDEEHRLEDAETESQSAVSETPQKRSDAVQKEVVDMKSEGQATVIQQLEQTIEDLRTKIAELERQYPALDTEVASGHQGLENGVTASGDVCLEALRLEEKEVRHHRILEAKSIQTSPTEEGGVLTLPP----VDGLPGRPPCPPG------AESGPQTKFCSEISLIVSPRRISVQLDSHQPTQSISQPPPP--PSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIP--QPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLP-TPQVCGFLPPPLPSGLFGLGMNQDKGSRKQPIEPCRPMKPLYWTRIQLHSKRDSSTSLIWEKIEEPSIDCHEFEELFSKTAVKERKKPISDTISKTKAKQVVKLLSNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSVVDLETLQALYENRAQSDELEKIEKHGRSSKDKENAKSLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRRKLELLQKLCETLKNGPGVMQVLGLVLAFGNYMNGGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLSYIVSYYLRNFDEDAGKEQCLFPLPEPQDLFQASQMKFEDFQKDLRKLKKDLKACEVEAGKVYQVSSKEHMQPFKENMEQFIIQAKIDQEAEENSLTETHKCFLETTAYFFMKPKLGEKEVSPNAFFSIWHEFSSDFKDFWKKENKLLLQERVKEAEEVCRQKKGKSLYKIKPRHDSGIKAKISMKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JL04-1", "uniprot_id": "FMN2_MOUSE", "id": "Q9JL04-1", "name": "Formin-2", "aln": "-MGNQDGKLKRSAGDASHEGGG-AEDAAGPRDAEITKKASGSKKALGKHGKGGGGSG---ETSKKKSKSDSRASVFSNLRIRKNLTKGKGACDSREDVLDSQALPIGELDSAHSIVTKTPDLSLSAEETGLSDTECADPFEVIHPGASRPAEAGVGIQATAEDLETAAGAQDGQRTSSGSDTDIYSFHSATEQEDLLSDIQQAIRLQQQQQQKLLLQD-----------SEEPAAPPTAISPQPGAFLGLDQFLLGP-----RSEAEKDTVQALPVRPDLPETTKS--LVPEHPPSSGSHLTSETPGYATAPSAVTDSLSSPAFTFPEAGPGEGAAGVPVAGTGDTDEECEEDAFEDAPRGSPGEEWVPEV-----EEASQRLEKEPEEGMRESITSAVVSLPGSPAPSPRCFKPYPLITPCYIKTTTRQLSSPNHSPSQSPNQSPRIKKRPDPSVSRSSRTALASAAAPAKKHRLEGGLTGGLSRSADWTEELGVRTPGAGGSVHLLGRGATA------DDSGGGSPVLAAKAPGAPATADGFQNVFTG-RTLLEKLFSQQENGPPEEAEKFCSRIIAMGLLLPFSDCFREPCNQNAGSSSAPFDQDQLYTWAAVSQPTHSMDYSEGQFPRREPSMWPSSKLPEEEPSPKDVDTEPKSSILESPKKCSNGVQQEVFDVKSEGQATVIQQLEQTIEDLRTKIAELEKQYPALDLEGPRGLSGLENGLTASADVSLDALVLHGKVAQPPRTLEAKSIQTSPTEEGRILTLPPPKAPPEGLLGSPAAASGESALLTSPSGPQTKFCSEISLIVSPRRISVQLDAQQ-IQSASQLPPP--PPLLGSDSQGQP-SQP--SLHTESETSHEHSVSSSFGNNCNVPPAPPLPCTESSSFMPGLGMAIPPPPCLSDITVPALPSPTAPALQFSNLQGPEMLPAPPQ-----------------------------------------------------PPPLPGLGVPPPP----------------------------------------------------PAPPLPGMGIPPPPPLPGMGIPPPPPLPGMGISPLPPLPGMGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGSGIPPPPALPGVAIPPPPPLPGMGVPPPAP-------------------------PPPGAGIPPPPLLPGSGPPHSSQVGSSTLPAAPQGCGFLFPPLPTGLFGLGMNQDRVARKQLIEPCRPMKPLYWTRIQLHSKRDSSPSLIWEKIEEPSIDCHEFEELFSKTAVKERKKPISDTISKTKAKQVVKLLSNKRSQAVGILMSSLHLDMKDIQHAVVNLDNSVVDLETLQALYENRAQSDELEKIEKHSRSSKDKENAKSLDKPEQFLYELSLIPNFSERVFCILFQSTFSESICSIRRKLELLQKLCETLKNGPGVMQVLGLVLAFGNYMNAGNKTRGQADGFGLDILPKLKDVKSSDNSRSLLSYIVSYYLRNFDEDAGKEQCVFPLAEPQELFQASQMKFEDFQKDLRKLKKDLKACEAEAGKVYQVSSAEHMQPFKENMEQFISQAKIDQESQEAALTETHKCFLETTAYYFMKPKLGEKEVSPNVFFSVWHEFSSDFKDAWKKENKLILQERVKEAEEVCRQKKGKSLYKVKPRHDSGIKAKISMKT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B718-1", "uniprot_id": "A0ACD6B718_DANRE", "id": "A0ACD6B718-1", "name": "", "aln": "MQTIQTIEMQLPVLRESFHSSPFRERAKERRKSSLSNLIRRQQQQLLREQQQS-------VLHQKQQPSSPLQGHAAHAQLVRSSSSPLCDLAEQIGELEKVRGIGRQGELSHRQSSDTASQPASSQQLLLAVKREREGLLREGEKVQGSTEREREEKRERESQSERTRSQHGLIAKGVRLLRIMGNQEAKQKKPTVTTGAEGEGNGAGTEDHVKKIKKSKS-------SAESGKKKSKSEGSKGSVFSNIRIRKGLS----RKVLSKEDVLDGGIRIKPADANGN---------SNGGISGDESCMPDSKQLTAESRQSTLDTTEDDVERETEGSGSDTDLCSYHSAAEAQDLLSDIQRTIRQMEGVDERQNCHSEDKERQVGFEGHVEVTHGPTRGSLACEGEPEKLEGASDSKYLNLICSGDTTGGVITS--KLKIESDGKVADIPNKADHLSSLSSDYSIQDAVPETNSVQDARAFTHSTS-NYSFQDNTGTSTSYESAEEILESSSLSSPLEECHYDSNSLTQSLEVGLNSSNHMSKINRVIFVPQKSISSVELNVDGDGPVEEVDRGFS---------------TQPRRKSSAASMTQWSSENFLGSGSRPRRTSSANLGVKPYPTIQTSYVKTTTRQLTSPIISPFTTPSPS------PMCPRKVGLEFGTGQGPYRAGSWRARRQRSCSIAGPVGCHEEWCEVIHDQSELIESGFQT------DRSRQTTSTFPDVFSGSSLLERCFLQWSSSEDD------------------------------SAMQDIERFCSRILDLGILQPFSDCIREPSTGSDVTDKPTFNKDQLYTWAPMGQHDIRTPGRLQRIWPPTLTAAQDGSTGQSGSVLEGSSVSIQELEQTIEELLEKISEIEKDNHVVDGKLGRKDRE------VAG-------------------------------------------------------------------------------------------------------------------------------FNQTIKQTKVNGQRVLHHVKAIQTSPVEEAFKFPVP----LSHQSQTPKLSDSATSPMGLPYTCSCQRTTSQPLSTPPPPQLP-----PPPPLSGM----TPPKPTGVIPPPPPLP--GFVPPPPVVGK-APPPPPLPGMVPPPPPPLPGMAPPPPPPFPGMTPPPPPP--------------------------PPGCGPPPPPLPPGIGP----------------------PPPFMGMGPPGMAHESVPLKAVIEPPRPMKPLYWTRIQLHAKKDAKSALVWENVQEPSVDFDEFVEMFAKSAVKEKKKPISDTITKSKAKQVVKLLSNKRSQAVGILMSSLHLDMKDIQNAILKMDCTVVDLETLQALYENRAQKEEMDQIEKHVKSSKDKEKPKPLDKPEQFLLQLSEVPQFSERVFCILFQSTFTECVTSVQRKLETLGRVCTALQSGQAVLQILGLVLAFGNIMNGGNRSRGQADGFSLDILPKLKDVKSSDNSQSLLSYIVAYYLRHFDEDAGKETCTYPLPEPQDLFQASQMKFEDFQRDLRKLRKDLNACSAEREKVCNISSDEHLQPFKDKMDDFLTKAKTELELQEKQLTDTQRIFLELSVFFSVKPKAGEKEVSPNTFFTVWHEFSSDFKELWKRENKSLLQERLKAAEETFKQAREKATYNVKPKQASGIKAKLGQKM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::: .. .... * * *. . :: :: * :. : . :*:. *.. . :: :: :. :. .: . *:. : : :* :.*.. . *::: *: .. : : .:* : *. . : :*.* :.. * . :.*.::: :: :. :::: : *.. : . . *:.:. :: * . . : . .:: * *. .*: : :. . *: . :. .:* . . . :* :.* * * . * *: ::: * . : . : *.* . .. * * .** ::* : :* .: . * .:.: * .* :: .... ::. : .:: . * . .: :: *. *. ... * . :: .... : * . .: :. : :*. ::: . :. : :** **.:: * :* .:.: :. : :..::: .: .: * * : . :* .* .:. . . * . * . * *. :. :* : .* .: :. *. .:. : .*::. * . :: . ** :* *.:*:. : :***.* : : :* : . .. :: *. * ** :. : .: : ..: :. .: ..:. * .. : * . :. * : * .: : * ..*: * * . . .* . . ..* ** . .. :. **** ** *****.* .** * ******** *: ****: * ******** ****.***:. *****:**: ***.* *** * ***** * ** ** *: ** :: . * *** **************:*:*:..:*:**:::***:* .** *:*:*:****:********:*:********************************:*::::* :****************.:*:::**** :******:.*.******** :** :*:**************:*.: *::**** * ::* :*:.* .*:*:********* **.**::*******.****************:*******:****:******** * :**.***:*************:*****:***:**..* ** ::** **:****::*::*: :** : * :* **:*:: *** :.:: :*** ********.**::*********: **:*** :****:* ***. :* : *: *::**:: ******:. * ", "identical_positions": 465, "similar_positions": 421, "identity": "26.59%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101108-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2W0-1", "uniprot_id": "A0A0G2K2W0_RAT", "id": "A0A0G2K2W0-1", "name": "Receptor-type tyrosine-protein phosphatase beta", "aln": "MEAEFYMTILTCLILGSLEGFQIVHVRKQQCLSINQKVIMSSCNGTSHNQQWLSTENGKFLHVKSGLCLSISNSSGGPFRPAVATPCAQAPRWTCHAQGGFLEVDNTSLFLKKQNRKVVVRKISKYLDSWMKLELNKEGRLVNESLCLKQAGLGTEVSVRITRNSAAPQIPTTSNTISYNPDHISNITETFLGSTAKTLGSTTETLRSTAETLGSTAEPYSQSSSKRDLPSLHMAGTTDTSWSPSTTPPFSSTTAETGVAEQVKCNFTVLESKVSSLSASIQWRTFGSPCNFSLIYSSDTSGPLWCHPILIDNFTYGCDPKDLQAGTIYNFRIVSLDGEERSLVLQTDPLPPARLEVNPERTTSTTLQVRWTPSSGKVTWYEVQLFDQNNQKIQEVQVQESATWSQYTFLNLTAGSSYKIGITAVSGGKRSFPVYTNGSTGPSPVEDIGISPNPNSLLISWSRGPGNVEQFRLMLMDKG--AIVQDTNVDKRDTSYAFRGLTPGHLYNVTIVTMASGLQNSRWKLGRTAPMEVSNLKVTSGGSLTSLNVKWQKPLGVIDSYSITLSHQGTVKESKTLPPRATEIQFKDLVPGRFYQVTIRCVSGELSAEKSAMG--RTVPEKVSNLVSYNEIWMKSFAVNWTPPAGDWDHYRILLF--NDSLVLLNTTVGKEETHFALEGLELIPGRQYEVEVIVESGNLRNSERCQG--RTVPLAVLQLRIKQANETSLGITWRAPLG--EWEKYTISLMDR-----ELFVIHKSLSKDAKEYTFTNLMPGRNYKATVTSMSGDLKQ--SASIQGRTVPAQVTDLEVSNQGMTS-SLFTNWTKALGDVEFYQVLLIHENV----VVKNESVSSDSSWYSFRALRSGSLYSVVVTTVSGGIPSRQVVAEGRTVPSSVSGVTVNNSGRNDYLSVSWLPAPGEVHHYVVTLSHDSKVVQ----------SLITAKFVSECSFSSLTPGRLYNVTITTKSGNYESHSFSEERTVPDKVQGISVSNSARSDYLKVSWVHATGDFDHYEVTIKNRDSFIQTKSIPKSENECVFARLVPGRLYSITVTTKSGQYEAS-EQGTGRTIPEPVKNLTLLNRSTEDLHVTWSRAN-GDVDQYEVQLLFNDMKVFPPIYLVNTATEYQFSALTPGRHYKILVLTISGDVQQPAFIEGLTVPSTVKNIHISANGATDRLTVTWSPGGGDVDSYVVSAFRQDEKVESHTLPKHGSEHTFHRLEAGATYRIAIVSVSGSLRNQIDVLGQTVPASVHGVVADNAYSSNSLTVSWQKALGMAERYDILLLSENGVLLSNTSEPATVKQHKFEDLTPGKKYKMQILTVSGGLFSKEVETEGRTVPAAVTNLRITENSSRHLSFSWTASEGELSWYNIFLYNPDKTLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPAAVNHLKGSNRNMTDSLWFSWSPASG-DFDFYELILYNPNGTKKENWREKDVTEWRFQGLIPGRKYTLYVVTHSGDLSNKVTG-EGRTAPSPPSLLSFADVANTSLAITWKGPPDWTDYNDFELQWLPGDALTVFNPYSSKKSEGRIVNGLRPGRSYQFSVKTVSG------------DSWKTYSKPISG---SVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDG----YSIECRKMDTQEIEFSRKLEKEKSLLNIMMLVPHRRYLVSIKVQSAGVTSEVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFAVVVREADSMDELRPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAESPDPDRSSKSFNIKLGGEMDSLGGKCDPSQQ------KFCDGPLKPHTAYRISIRAFTQLFDEGLKEFTKPLYSDTFFSMPITTESEPLFGVIEGVSAGLFLIGMLVALVAFFICRQKASHSRERSSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEDLKDVGRSQSCDIALLPENRGKNRYNNILPYDASRVKLCNVDDDPCSDYINASYIPGNNFRREYIATQGPLPGTKDDFWKMAWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDPLYYGDLILQMVSESVLPEWTIREFKICSEEQLDAHRLLRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFVALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRNEQENPLFPIYENVNPEYHRAQQGLYERLSLTFLF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B2RU80-1", "uniprot_id": "PTPRB_MOUSE", "id": "B2RU80-1", "name": "Receptor-type tyrosine-protein phosphatase beta", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRHGALTALW-------ITLSVVQTGVAEQVKCNFTLLESRVSSLSASIQWRTFASPCNFSLIYSSDTSGPMWCHPIRIDNFTYGCNPKDLQAGTVYNFRIVSLDGEESTLVLQTDPLPPARFEVNREKTASTTLQVRWTPSSGKVSWYEVQLFDHNNQKIQEVQVQESTTWSQYTFLNLTEGNSYKVAITAVSGEKRSFPVYINGSTVPSPVKDLGISPNPNSLLISWSRGSGNVEQYRLVLMDKG--AIVQDTNVDRRDTSYAFHELTPGHLYNLTIVTMASGLQNSRWKLVRTAPMEVSNLKVTNDGRLTSLNVKWQKPPGDVDSYSITLSHQGTIKESKTLAPPVTETQFKDLVPGRLYQVTISCISGELSAEKSAAG--RTVPEKVRNLVSYNEIWMKSFTVNWTPPAGDWEHYRIVLF--NESLVLLNTTVGKEETHYALDGLELIPGRQYEIEVIVESGNLRNSERCQG--RTVPLAVLQLRVKHANETSLGITWRAPLG--EWEKYIISLMDR-----ELLVIHKSLSKDAKEFTFTDLMPGRNYKATVTSMSGDLKQ--SSSIKGRTVPAQVTDLHVNNQGMTS-SLFTNWTKALGDVEFYQVLLIHENV----VVKNESVSSDTSRYSFRALKPGSLYSVVVTTVSGGISSRQVVAEGRTVPSSVSGVTVNNSGRNDYLSVSWLPAPGEVDHYVVSLSHEGKVDQ----------FLIIAKSVSECSFSSLTPGRLYNVTVTTKSGNYASHSFTEERTVPDKVQGISVSNSARSDYLKVSWVHATGDFDHYEVTIKNRESFIQTKTIPKSENECEFIELVPGRLYSVTVSTKSGQYEAS-EQGTGRTIPEPVKDLTLLNRSTEDLHVTWSRAN-GDVDQYEVQLLFNDMKVFPHIHLVNTATEYKFTALTPGRHYKILVLTISGDVQQSAFIEGLTVPSTVKNIHISANGATDRLMVTWSPGGGDVDSYVVSAFRQDEKVDSQTIPKHASEHTFHRLEAGAKYRIAIVSVSGSLRNQIDALGQTVPASVQGVVAANAYSSNSLTVSWQKALGVAERYDILLLNENGLLLSNVSEPATARQHKFEDLTPGKKYKMQILTVSGGLFSKESQAEGRTVPAAVTNLRITENSSRYLSFGWTASEGELSWYNIFLYNPDRTLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPAAVNHLKGSHRNTTDSLWFSWSPASG-DFDFYELILYNPNGTKKENWKEKDVTEWRFQGLVPGRKYTLYVVTHSGDLSNKVTG-EGRTAPSPPSLLSFADVANTSLAITWKGPPDWTDYNDFELQWFPGDALTIFNPYSSRKSEGRIVYGLHPGRSYQFSVKTVSG------------DSWKTYSKPISG---SVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDG----YSIECRKMDTQEIEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPQPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFAVVVREADSMDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAESPDS--SSKSFNIKLGAEMDSLGGKCDPSQQ------KFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSMPITTESEPLFGVIEGVSAGLFLIGMLVALVAFFICRQKASHSRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEDLKDVGRSQSCDIALLPENRGKNRYNNILPYDASRVKLCNVDDDPCSDYINASYIPGNNFRREYIATQGPLPGTKDDFWKMAWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDPLYYGDLILQMVSESVLPEWTIREFKICSEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFVALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRAKKLRNEQENPLFPIYENVNPEYHR--DAIYSRH-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23467-1", "uniprot_id": "PTPRB_HUMAN", "id": "P23467-1", "name": "Receptor-type tyrosine-protein phosphatase beta", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLSHGAGLALW-------ITLSLLQTGLAEPERCNFTLAESKASSHSVSIQWRILGSPCNFSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLD-EERTVVLQTDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGSTVPSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKG--ILVHGGVVDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGELSAQKMAVG--RTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQYRILLF--NDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSERCQG--RTVPLAVLQLRVKHANETSLSIMWQTPVA--EWEKYIISLADR-----DLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKN--SSSVKGRTVPAQVTDLHVANQGMTS-SLFTNWTQAQGDVEFYQVLLIHENV----VIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQ----------SLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEAN-EQGNGRTIPEPVKDLTLRNRSTEDLHVTWSGAN-GDVDQYEIQLLFNDMKVFPPFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLTENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASG-DFDFYELILYNPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTA-ESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRIVYGLRPGRSYQFNVKTVSG------------DSWKTYSKPIFG---SVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDG----YSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKPEQQHPLPSYLEYRHNASIRVYQTNYFASKCAENPNS--NSKSFNIKLGAEMESLGGKCDPTQQ------KFCDGPLKPHTAYRISIRAFTQLFDEDLKEFTKPLYSDTFFSLPITTESEPLFGAIEGVSAGLFLIGMLVAVVALLICRQKVSHGRERPSARLSIRRDRPLSVHLNLGQKGNRKTSCPIKINQFEGHFMKLQADSNYLLSKEYEELKDVGRNQSCDIALLPENRGKNRYNNILPYDATRVKLSNVDDDPCSDYINASYIPGNNFRREYIVTQGPLPGTKDDFWKMVWEQNVHNIVMVTQCVEKGRVKCDHYWPADQDSLYYGDLILQMLSESVLPEWTIREFKICGEEQLDAHRLIRHFHYTVWPDHGVPETTQSLIQFVRTVRDYINRSPGAGPTVVHCSAGVGRTGTFIALDRILQQLDSKDSVDIYGAVHDLRLHRVHMVQTECQYVYLHQCVRDVLRARKLRSEQENPLFPIYENVNPEYHR--DPVYSRH-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ITJ9-1", "uniprot_id": "A0A0R4ITJ9_DANRE", "id": "A0A0R4ITJ9-1", "name": "protein-tyrosine-phosphatase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLRNKAFHAAVW-------AACGILSTMVVDATECSIEIVKVISSTESIRLTLDNANVKCQYTVSVKDRHTDSKGCR---QDREHSKCQIESLDPGTWYHLDVISTL-------------------------------------------------DEKQQSQRAVTLQTR----------------------------------------PSAVENLQVSGDANSLDVSWQPGKGKTERYWIVLIDSSGRDSAWNSTVASTATSYTMKGLISGRLYNITVVTEVGELQNSASTQAQTAPASVSKLRTENNGDRNSIRVLWDKASGDVDSYLVSLTTPGSNSIEKVLPPDDTYVVFENLSPGKGYQVSVSTRSGALSNKTWITG--KADPGKVSDLVIENLSVRGALKISWTPPSGEWEHIRVALS--NGSEVLRNQTVGRTAKEILLSGLNLLPGRVYRMAVSVENGGLANTVIYEG--EIGLPPVSQLHVRHSDETSLSALWAHAASSSSRDGYIIQLFQSNT---STVIQTRNLSRDMRECTFNVLTPGRLYDITVTTTAKIIRS--SATLQGRTQPLKVNHLKLSNKGSTD-SLNASWEKPLGDLDFYHMLLLRDQQ----TVHNITASANTTSRLLPFLRPGALHKILVTTISGSQTSKLAEAECRTVPAAVSDITVTNSGP-DFLNVSWKAAEGDVDNYVVMLKDQEKIVH----------TLATSKATTECVFRSLVSGRLYSISIATHSGSYRNQTLLQERTKPSTVQNPTAIHSARDDFLKLYWNHASGDYDYYVVTIEHNGTRLQSQKLNRTQSDCAFSDLVPGRLYNLTVSTWSGQHYSA-VSIYGRTFPGAVGNLSLTERGGTFLRVSWTSAP-GDVDHYELQILFNDTQVSAAVNLSSAIGEHLFSALTPGRLYKIVLSTHSGSYQRAEILEGRTVPSQVQSVHLSAGTADGSLRVSWSSADGDLDFYSVSLFQETHLQDSRRVPKHITQAEFYNLIPGQLYSVTVQSVSGSQTNNSTTTGRTEPSTVTGLRADNELSTHSLLVSWNPAVGVHDGYRLWLLDDGGTNIHNASVPAASRHHLFENLTPGRRYQAHVRTLSGTAESKDVVAEGQTRPSAVSALHVCSNTSSDLSFCWASAVGWVDGYELYLYDRDETLHYHTTLGSDALGWSFTLLQPGTHYKMTITSKSGKLSNQSSVWAHTAPASVPELHVENQGQTDSLLLSWTPAPG-GLTGYSVTVDG-----REQRVGPEVTQVVFHSLVAGRLYLATVQTWSEDLSNSTTA-VGRTVPAAPSSVSVS-CSGGSVDMKWHVP-DTGDYEDFEVTWFPQDTLYIS----HLRPTQRILEGLHPGRLYNISLRTVSGK----------RHSPVTYSRPVYH---TIRTPPLPAPSIHCFPLSSTSVSCSWTPPHSDYDG----FVVQCHRQGSGKAVYTHTLGNHTLSQQFDRLEPFKNYTIYVAVMSGDKQSSTVKNSVITMIDRPPVPPVTVRVNEHSAVITHFTIRFKFNCSWFSDANGAIRYFTIIATESNDVDNGLPEQRHPLPSYLDYRQNHSIKAYQTGYFHSTCAEGSDG--KVQVFEINLGAGMKHLGGACKLDPESIQHGSHLCDGPLRSRTSYRLSVRAFTQLFDEENREFPHPLYTDTYLSLPLLTQSAPRSGLTGGITAALFLITMVLALTALLIYRKRAHKIAVQESPVMKMCKWKALPT-----SQMCLRIRSPVQAANFESHLAKLQSDSSYLLSEEFEGLKDVGRIQTQNAARLLGNRNKNRYNNILPYDSTRVRLSCLEDDPCSDYINANYIPGNNFRWEYIATQGPLPGTKDDFWRMVWEQNVHSLVMVTQCVERGMVKCDHYWPTDSEPLCYGDIVVQLLSEKVFPEWTIRDFKISCESQLRYPRMVRQFHYTIWPDHGVPDTTQSLIQFVRTVRDFINRTNSPGISVVHCSAGVGRTGTFIVLDRALQQLDRNCTVDIYGCVFDLRLHRSYMVQTECQYAYIHQCVRDVLRARKLGCERDNPLFPIYNNII---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P35992-5", "uniprot_id": "PTP10_DROME", "id": "P35992-5", "name": "Tyrosine-protein phosphatase 10D", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLYQLSKA----TTRIRLKRQKAVPQHRWLWS-----------LAFLAAFTLKDVRCADLAISIPNNPGLDDGASYRLDYSPPFG--------YPEPNTTIASREIG---DEIQFSRALPGTKYNFWLYYTNFTHHDWLTWTVTITTAPDPPSNLSVQVRSGKNAIILWSPPTQGSYTAFKIKVLGLSEASSSYNRTFQVNDNTFQHSVKELTPGATYQVQAYTIYDGKESVAYTSRNFTTKPNTPGKFIVWFRNETTLLVLWQPPYPAGIYTHYKVSIEPPDANDSVLYVEKEGEPPGPAQAAFKGLVPGRAYNISVQTMSEDEIS-LPTTAQYRTVPLRPLNVTFDRDFITSNSFRVLWEAPKGISEFDKYQVSVATTRRQSTVPRS-NEPVAFFDFRDIAEPGKTFNVIVKTVSGKVTSWPATGDVTLRPLPVRNLRSINDDKTNTMIITWEADPASTQDEYRIVYHELETFN--------GDTSTLTTDRTRFTLESLLPGRNYSLSVQAVSKKMESNETSIFVVTRPSSPIIEDLKSIRMGLNISWKSDVNSKQEQYEVLYSRNGTSDL-RTQKTKESRLVIKNLQPGAGYELKVFAVSHDLRSEPHAYFQAVYPNPPRNMTIETVRSNSVLVHWSPPESGEFTEYSIRYRTDSEQQWVRLPSVRST-EADITDMTKGEKYTIQVNTVSFGVESPVPQEVNTTVPPNPVSNIIQLVDSRNITLEWPKPEGRVESYILKWWPSDNP------------------------------------------GRVQTKNVSENKSADDLST--------------------------------------VRVLIGELMPGVQYKFDIQTTSYGILSGITSLYPRTMPLIQSDVVVANGE----------------------------------------------------------------------------------KEDERD-TITLSYTPTPQSSSKFDIYRFSLGDAEIRDKEKLANDTDRKVTFTGLVPGRLYNITVWTVSGGVASLPIQRQDRLYPEPITQLHATNITDTEISLRWDLP--KGEYNDFDIAYLTADN---LLAQNMTTRNEITISDLRPHRNYTFTVVVRSG----------TESSVLRSSSPLSASFTTNEAVPGRVERFHPTDVQPSEINFEWSLPSSEANGVIRQFSIAYTNINNLTDAGMQDFESEEAFGVIKNLKPGETYVFKIQAKTAIGFGPEREYRQTMPILAPPRP--ATQVVPTEVYRSSSTIQIRFRKNYFSDQNGQVRMYTIIVAEDDAKN----ASGLEMPSWLDVQSYSVWLPYQAIDPYYPFENRS-------------VEDFTIGTENCDNHKIG------YCNGPLKSGTTYRVKVRAFTGADK----------FTDTAYSFPIQTDQDNTSLIVAITVPLTIILVLLVTLLFYKRRRNNCRKTTKDSRANDNMS-----------LPDSVIEQNRPILIKNFAEHYRLMSADSDFRFSEEFEELKHVGRDQPCTFADLPCNRPKNRFTNILPYDHSRFKLQPVDDDEGSDYINANYVPGHNSPREFIVTQGPLHSTRDDFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPNDTVPVFYGDIKVQILNDSHYADWVMTEFMLCRGS---EQRILRHFHFTTWPDFGVPNPPQTLVRFVRAFRDRIG--AEQRPIVVHCSAGVGRSGTFITLDRILQQINTSDYVDIFGIVYAMRKERVWMVQTEQQYICIHQCLLAVLEGKENIVGPAREMHDNEGYEGQQVQLDENGDVVATIEGHLSHHDLQQAEAEAIDDENAAILHDDQQPLTSSFTGHHTHMPPTTSMSSFGGGGGGHTNVDAPDRXHSVVNQSDNNNSVVIVLVDNKPSSMICKDSKGGNIDVLESQQQQQQQQQQQPNQGGHNITTISAINGYNTLQHRRKSQLITFSSSSCDIKNSLSHEYINGSNGSAANGPPSSGSGSGSGPGSNRASRANVRLSFAEEDVMILPQNHSQQSNHQDDEVFTRRRSLLEVEIGVEVGEDGELAPHEMEEDLEEEDEDEELYMHDEFETHIDTKSNNANDDSGGGSYEDSHALHSSLGGSNRNSLEKDDDDIEVDVISTDVSCYDQLLGSSCNTRNGDDDDIATLVGDGDYSTTKLSKASRLSGAGVGGLVVSGGGGGTAIGGGIAVNGGGVLGNGVGSEAGGGIIYANPFMDDEGIAESGM", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W4F5-1", "uniprot_id": "Q9W4F5_DROME", "id": "Q9W4F5-1", "name": "protein-tyrosine-phosphatase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDCATRKQQQLRAHHQQQQIQIQTHG----RKRQQLQKQRHNHHHYYQNSQQQQKHFVWLVVGILTIFLAQHANAADLVINVPN-ASSNANAFYRIDYSPPFG--------FPEPNTTIPASDIG---KDIKFSRALPGTEYNFWLYYTNSTHREQLTWTVNITTAPDPPANLSVQLRSSKSAFITWRPPGSGRYSGFRIRVLGLTDLPFERSYSLEGNE-TLQLSAKELTPGGSYQVQAYSVYQGKESVAYTSRNFTTKPNTPGKFIVWFRNETTLLVLWQPPFPAGIYTHYRVSITPDDAIQSVLYVEREGEPPGPAQAAFKGLVPGREYNISVQTVSEDETSSVPTTARYLTVPERVLNVTFDEAYTTSSSFRVRWEPPRTYSEFDAYQVMLSTSRRIFNVPRAANGDSVYFDYPDILEPGRTYEVVVKTIADNVNSWPASGEVTLRPRPVRSLGGFLDDRSNALHISWEPAETGRQDSYRISYHEQTNASEVPAPFPVAAESQITTNLTEYTLDSLLAGRRYLIAVQALSKGVASNASDITRYTRPAAPLIQELRSIDQGLMLSWRSDVNSRQDRYEVHYQRNGTREE-RTMATNETSLTIHYLHPGSGYEVKVHAISHGVRSEPHSYFQAVFPKPPQNLTLQTVHTNLVVLHWQAPEGSDFSEYVVRYRTDASP-WQRISGLHEN-EARIKDMHYGERYLVQVNTVSFGVESPHPLELNVTMPPQPVSNVVPLVDSRNLTLEWPRPDGHVDFYTLKWWPTDEE------------------------------------------DRVEFKNVTQLEDLSSPS---------------------------------------VRIPIEDLSPGRQYRFEVQASSNGIRSGTTHLSTRTMPLIQSDVFIANAG----------------------------------------------------------------------------------HEQGQDETITLSYTPTPADSTRFDIYRFSMGDPTIKDKEKLANDTERKLSFSGLTPGKLYNVTVWTVSGGVASLPVQRLYRLHPLPISDLKAIQVAAREITLHWTAP--AGEYTDFELQYLSADEEAPQLLQNVTKNTEITLQGLRPYHNYTFTVVVRSGSIQGTDFADVSVSTLMRSSAPISASYQTLTAPPGKVDYFQPSDVQPGEVTFEWSLEPAEQHGPIDYFRITCQNADDAADVSSYEFPVNATQGKIDGLVPGNHYIFRIQAKSALGYGAEREHIQTMPILAPPVP--EPSVTPLEVSRTSSTIEISFRQGYFSNAHGMVRSYTIIIAEDVGKN----ASGLEMPSWQDVQAYTVWLPYQAIEPYNPFLTSNGS-----RKSSLEAEHFTIGTANCDKHQAG------YCNGPLRAGTTYRIKIRAFTDEDK----------FTDTVYSSPITTERSDT-VIVAATVSAVLLVAMVLVVVYCQHRCQLIRRASKLARMQDELAA----------LPEGYITPNRPVHVKDFSEHYRIMSADSDFRFSEEFEELKHVGRDQACSFANLPCNRPKNRFTNILPYDHSRFKLQPVDDDDGSDYINANYMPGHNSPREFIVTQGPLHSTREEFWRMCWESNSRAIVMLTRCFEKGREKCDQYWPVDRVAMFYGDIKVQLIIDTHYHDWSISEFMVSRNC---ESRIMRHFHFTTWPDFGVPEPPQSLVRFVRAFRDVIG--TDMRPIIVHCSAGVGRSGTFIALDRILQHIHKSDYVDIFGIVFAMRKERVFMVQTEQQYVCIHQCLLAVLEGKEHLLADSLELHANDGYEVTKIYLERQ---------------------------------------------------PQTKMG------------TLPIR-------------ASLAMAEKLDADLMTNKD--------EDEDQEQQQQQQ--------------------------------------------------------------------------------------------------------------------LQLATEVKPKGSNDDEEDEED-DDDDDDDQQPLNNETTATLSSASCSSS----------THDVHVVL----QEAIEKPKQ--EQERICAGTQSHADTESDNTDSDDDDED----------------------------------GDGKVAKDGAVADEDGWWY-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . . * . * :. . . . .: :. . * . .: : *. ** *:. : . : * :* :: .* * : :: : . . :. . * ** *.: . . . . . :: : :**:* * . * :.: : .. . . : :*. * *** * :* : : . .:: : * * : .: . . *. *: . * . :* : : . ..* ..::*.*::. * . : * .* .: .. : : ::* .. .: :. . : ** .** * ::: : * .: .* . .... : * * ... . :. .:. : * ** *.:.* : * : . * . :::: : : * . .:. .* :: : . * :. : *. * : : * * . : . * .. . :: : : *. * :: * :. : . .:. .* . * : : :* ** :*: .: : * * :* * : : : . : . :. * :* . :* . : * . : . :*: : * .* .*: * * * * .::. * * . : : : .: : * * :* **:: ::. * : .*:* : * :.: . ** : * *: : : * :: .. : .* :: .* : : . . : . : * * . * . : . :. . : * ** * * .. : :*.: .. .:**: :* :: :::: * : . :**: : : **: : *. *:***:. *:**:.:**** . ::** * *: *: . ::: :::.: : : .: . *: :* * :.:**.: :*:*:* **.*** *. * * ** ***:.****** :*.:* ::** ******.*:**:* *:*.***** .*:::**:* **.* : :**:*:*.*:* ***:*** * .: ***: :*:: :. :* : :* :. *::*:**:* ***.***:..*:*::***:.** *. :*********:***:.*** **::. . ***:* *. :* .* ***** ** :***: **..:: :. ", "identical_positions": 270, "similar_positions": 408, "identity": "9.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101109-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P20334-1", "uniprot_id": "TNR9_MOUSE", "id": "P20334-1", "name": "Tumor necrosis factor receptor superfamily member 9", "aln": "MGNNCYNVVVIVLLLVG----------CEKVGAVQNSCDNCQPG----TFCR-KYNPVCKSCPPSTFSSIGGQPNCNICRVCAGYFRFKKFCSSTHNAECECIEGFHCLGPQCTRCEKDCRPGQELTKQGCKTCSLGTFNDQNGTGVCRPWTNCSLDGRSVLKTGTTEKDVVCGPPVVSFSP-STTISVTPEGGPGGHSLQVLTLFLALTS-ALLLALIFITLLFSVLKWIRKKFPHIFKQPFKKTTGA----AQEEDA--CSCRCPQEEEGGGGGYEL-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07011-1", "uniprot_id": "TNR9_HUMAN", "id": "Q07011-1", "name": "Tumor necrosis factor receptor superfamily member 9", "aln": "MGNSCYNIVATLLLVLN----------FERTRSLQDPCSNCPAG----TFCDNNRNQICSPCPPNSFSSAGGQRTCDICRQCKGVFRTRKECSSTSNAECDCTPGFHCLGAGCSMCEQDCKQGQELTKKGCKDCCFGTFNDQK-RGICRPWTNCSLDGKSVLVNGTKERDVVCGPSPADLSPGASSVTPPAPAREPGHSPQIISFFLALTSTALLFLLFFLTLRFSVVKRGRKKLLYIFKQPFMRPVQT----TQEEDG--CSCRFPEEEEG---GCEL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IT02-1", "uniprot_id": "A0A0R4IT02_DANRE", "id": "A0A0R4IT02-1", "name": "", "aln": "-MEMVFALLLLLLAAAHSLESGCQNWDISTVNKVEVCCVSCKPGNRLVKKCGLDPKDLCSPCEKDTFIANPTERSCKRCSQCIGLMRVKTNCTASSDTVCACKEGYQCSDHRCSFCNKVCGKGEQPKGRQCEPCPPGTYNDKT-HHNCVNWTKCTQPDHQIIAAGTASSDVICG-LTAVTKPWKNVTRNDADIGTVSTIIIIIFGLLCISFPVATFILLEWRRRKDGQKERRNPLAAEAANAETVSEESSFCFPQQERGGSSSSSSSQSSQSSLLSQDIGPLQP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: :* . . :: * .* .* . * . : :*..* .:* : : .*. * * * :* :. *::: :: * * *::* . *: *:: * *:: . : *: * **:**:. * **:*: .:.:: ** . **:** . .* . . . :: :*.:: . : *: . * *: : :. . : .*:* . .*. .:..:. . :: ", "identical_positions": 46, "similar_positions": 89, "identity": "16.2%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101110-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N0Z8-1", "uniprot_id": "PUSL1_HUMAN", "id": "Q8N0Z8-1", "name": "tRNA pseudouridine synthase-like 1", "aln": "MSSAPASGSVRARYLVYFQYVGTDFNGVAAVRGTQRAVGVQNYLEEAAERLNSVEPVRFTISSRTDAGVHALSNAAHLDVQRRSGRPPFPPEVLAEALNTHLRHPAIRVLRAFRVPSDFHARHAATSRTYLYRLATGCHRRDELPVFERNLCWTLPADCLDMVAMQEAAQHLLGTHDFSAFQSAGS--PVPSPVRTLRRVSVSPGQASPLVTPEESRKLRFWNLEFESQSFLYRQVRRMTAVLVAVGLGALAPAQVKTILESQDPLGKHQTRVAPAHGLFLKSVLYGNLGAASCTLQGPQFGSHG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2ADA5-1", "uniprot_id": "PUSL1_MOUSE", "id": "A2ADA5-1", "name": "tRNA pseudouridine synthase-like 1", "aln": "MGSCGAVGSVRARYLVFLQYLGTDFNGVAAVRGNPRAVGVLNFLEEAAKRLNSVDPVRFTISSRTDAGVHALSNAAHLDIQRRPGQSPFSPEVVAKALNTHLKHPAIRVLKAFRVPNDFHARHAATSRTYQYRLATGCSWPNQLPVFEQNVCWALQTEYLDMAAMQEAAQHLLGTHDFSAFQSAGS--PVTNTVRTLRRVSVSPGPASPFVLPEGSRRLQFWTLEFESQSFLYRQVRRMTAVLVAVGLGILAPTQVKVILESQDPLGKYQARVAPARGLFLKSVLYDNFGPTS------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QJL2-1", "uniprot_id": "F1QJL2_DANRE", "id": "F1QJL2-1", "name": "tRNA pseudouridine synthase", "aln": "------MQQTVARYLIFFQYTGSKYSGVMKAPAHQAVQGVGNHLENAVRKLKPVNEVCVSISSRTDTGVHALCNSAHVDIQRRADKPPLSEQSLLEALNFQLKEEPIRITRAYRVHSDFHARYQAQSRTYVYRLALGCQHHTLMPLTEKDLCWALRDTRLNIDAMREASALLLGTHDFSTFRALSSDAPFKCPVKTLDLAQLEPGES--FSQRHFQRDIQFWELTFKSRSFLYRQVRRMTGVLVAIGQGRLSVSKIQDLLEARDSLAFPNNLTAPAHGLFLTNVQYRDTDLVASMSEEQ------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. ****:::** *:.:.** . . . ** *.**:*..:*:.*: * .:******:*****.*:**:*:***..:.*:. : : :*** :*:. .**: :*:** .*****: * **** **** ** :*: *:::**:* *:: **:**: ********:*:: .* *. .*:** ..:.** : : . .* ::** * *:*:***********.****:* * *: :::: :**::*.*. : .***:****..* * : . .: ", "identical_positions": 125, "similar_positions": 95, "identity": "40.98%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101112-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AP18-1", "uniprot_id": "PLCH2_MOUSE", "id": "A2AP18-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2", "aln": "MGGLAWGPSRAAGSSWVNASGTWEQPLRGFSGLQGGRRRGRGEKGIPEEPLCQLTPQLGLSLRVPFGLGDYGLDMPGPQPSAASQTTGAVACLAEVLLWVGGSVVVSPRWQLSLVVERCMSAMQEGTQMVKLRGSSKGLVRFYYLDEHRSCLRWRPSRKNEKAKISIDSIQEVSEGRQSEIFQRYPDSSFDPNCCFSIYHGSHRESLDLVSPSSEEARTWVTGLRYLMAG----ISDEDSLARRQRTRDQWLKQTFDEADKNGDGSLSISEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRDLYLLMLTYSN-HKDHLDASDLQRFLEVEQKMNGVTLESCQNIIEQFEPCLENKSKGMLGIDGFTNYTRSPAGDIFNPEHNRVHQDMT-QPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVLQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHCSVVQQKKMAQYLTDILGDKLDLSSVSSEDATMLPSPQMLKGKILVKGKKLPANISEDAEEGEVSDEDSADEMEDDCKLLNGDASTNRKRVENIAKKKLDSLIKESKIRDCEDPNDFSVSTLSPSGKLGRKAEAKKGQSKVEEDVEAGEDSGVSRQNSRLFMSSFSKRKKKGSKIKKVASVEEGDETLDSPGSQSR---GTARQKKTMKLSRALSDLVKYTKSVGTHDVEIEV-VSSWQVSSFSETKAHQILQQKPTQYLRFNQHQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGD-------CGYVLKPQCMCQGVFNPNSEDPLPGQLKK-----QLALRIISGQQLPKPRDSVLGDRGEIIDPFVEVEVIG-----LPVDCSK--------EQTRVVDDNGFNPMWEETLVFTVHMPEIALVRFLVWDHDPIGRDFIGQRTLAFSSIMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQTLGLKGLFLRGTKPGSLDSHAAGQPLPRPSVSQRLLRRTASAPTKSQKPSRKGFPELALGTQDAGSEGAADDVAPSSPNPALEAPTQERSGSSSPRDTRLFPLQRPISPLCSLEPIAEEPALGPGLPLQAAAPTGPSQEGSQCPVGLGAKVTSSQQTSLGAFGTLQLRIGGGRENEEPPLRPHNGGISSGPREGTSGRQTDSKSRSRVPGHLPVVRRAKSEGQVLSELS----------PTPAVYSDATGTDRLWQRLEPGSHRDSVSSSSSMSSNDTVIDLSLPSLGLCRSRESIPGVSLGRLTSRPCLASAARPDLPPVTKSKSNPNLRVAGGLPTAPDELQPRPLAPRLTGHHPRPPWHHLTLVGLRDCPVSAKSKSLGDLTADDFAPSFQGSTSSLSCGLGSLGVAHQVLEPGIRRDALTEQLRWLTGFQQAGDITSPTSLGPAGDGSVGGPSFLRRSSSRSQSRVRAIASRARQAQERQQRLRGQDSRGPPEEERGTPEGACSVGHEGCVDVPMPAKGAPEQVCGAADGQLLLRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75038-1", "uniprot_id": "PLCH2_HUMAN", "id": "O75038-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2", "aln": "--------------------------------------------------------------------------MSGPWPSPDSRTKGTVAWLAEVLLWVGGSVVLSSEWQLGPLVERCMGAMQEGMQMVKLRGGSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRYPDGSFDPNCCFSIYHGSHRESLDLVSTSSEVARTWVTGLRYLMAG----ISDEDSLARRQRTRDQWLKQTFDEADKNGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMSTRRDLYLLMLTYSN-HKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLLGIDGFTNYTRSPAGDIFNPEHHHVHQDMT-QPLSHYFITSSHNTYLVGDQLMSQSRVDMYAWVLQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIENHCSVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISEDAEEGEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFSVSTLSPSGKLGRK-------SKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGDEGQDSPGGQSR---GATRQKKTMKLSRALSDLVKYTKSVATHDIEMEA-ASSWQVSSFSETKAHQILQQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLNRAKFSANGG-------CGYVLKPGCMCQGVFNPNSEDPLPGQLKK-----QLVLRIISGQQLPKPRDSMLGDRGEIIDPFVEVEIIG-----LPVDCSR--------EQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDHDPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLRGPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVADDVVPPGPGPAPEAPAQEGPGSGSPRDTRPLSTQRPLPPLCSLETIAEEPAPGPGPPPPAAVPTSSSQGRPPYPTGPGANVASPLEDTE--------------EPRDSRPRPCNGEGAGGAYERAPGSQTDGRSQPRTLGHLPVIRRVKSEGQVPTEPLGGWRPLAAPFPAPAVYSDATGSDPLWQRLEPCGHRDSVSSSSSMSSSDTVIDLSLPSLGLGRSRENLAGAHMGRLPPRPHSASAARPDLPPVTKSKSNPNLRATGQRPPIPDELQPRSLAPRMAGLPFRPPWGCLSLVGVQDCPVAAKSKSLGDLTADDFAPSFEGGSRRLSHSLGLPGGTRRVSGPGVRRDTLTEQLRWLTVFQQAGDITSPTSLGPAGEGVAGGPGFVRRSSSRSHSRVRAIASRARQAQERQQRLQGLGRQGPPEEERGTPEGACSVGHEGSVDAPAPSKGALGPASAAAENLVLLRL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PVI9-1", "uniprot_id": "A0A8M9PVI9_DANRE", "id": "A0A8M9PVI9-1", "name": "Phosphoinositide phospholipase C", "aln": "--------------------------------MNSSPAMAPSSPVLFSPSLARRPPSPGRRPNTNFRS-----ASPSIMTSPKLWQKAAISRLAEEFFWIGGSIVASPKWRMGQIVERCMCNMQAGSQMIKLRGKSKALVRLFYLDEHKSCIRWRPSRKHERAKITIDSIHEVCEGMRTEVFRRFANNNFDPNCCFSIYHGDHVESLDLVSTNGEEARTWITGLKYLLAG----ISDEDSLAKRQRTRDQWLRQTFSEADKNGDGNLSIGEVLQLLHKLNVNLPKQKVREMFQEADTDENQGSLTFEEFCTFYKLISTRRDLYLLMISYSN-HKEHLDLNDLQRFLESEQKMVNVTKEYCKMIINQFEPCSQNQSHVVLGIDGFTNYMRSPAGDIFNPEHYQVNQDMT-QPLTNYYIASSHNTYLTGDQLLSQSRVDMYAYVLQMGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVVETINKYAFAKTQFPVILSIENHCTVPQQKKMAQYLMEVLQDKVDLSNINTNESRRLPSPEDLKGKILVKGKKLPANIDADADEGDVSDEDSGEEDEEEELQLNGDTTEG-----------------------------------------------------APESASADESKKRSRRK---FMGSFRRKKKKQVKVKKKPIVSDSDTEPEITSTNDKQVINYGKRRKTMRLSRALSDLVKYTKSVRVHDIETQAYMSSWQVSSLNESITNQILQLKPAQLVRFNQRQLLRVYPSNYRVDSSNFNPQPFWNAGCHLVALNYQTEGRMLQLNRAKFAANGN-------CGYVLKPKCMCKGAFNPVLEDPLPGHRKS-----QLVLKIISGQQLPKPKDSMLGDRGEIIDPFVEVEIIG-----LPIDCNK--------QQTRVVDDNGFNPTWEETLVFTLHMPQIALVRFMVWDHDPIGRDFIGQRTISFKSMMPGYRHVYLEGMEEASIFVHVAVNDITGKVKSSNAVKQLIQKNLMQTSEDG-------TRKSFAPNFLRKSGKNQSKVVK-------VECYTKEDFLNRRYSDDVSS--------------------KDS------RSTSQSASLLRGAQSEPLKRAHRVSFQEPEGSHEPRRRLSS-----------------------------------IPYTGGAAVDYTNLAFDSHSSSELDIQTFSHLEDN------------------------------TESKQNDSLSSKLEFESTDIPKSPASTLNEQCLSRQISAANEHSEQKPE----------MSKMIHSVPDPLNFHPIPDGVLDPSRGTLN--TLVPQNKFRSSLDARLN-----PRWQPLSIP-----ATPALNRRMNDKGTPN---SLLKGCRSQSVPRRRPTSPPNTPG-HIRRDPINQYFLPQCSYTTANDLVPNNHNIAESES----------SSLSSLDSLDLSTLPCRFPDNQQQTMGTLQREMNALFEQKIQEIRCHS--------PLFFRDSSTL-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32383-1", "uniprot_id": "PLC1_YEAST", "id": "P32383-1", "name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1", "aln": "--------------MTESAIDDQRFNLTKELQRHSCRDQGKITQKDDALDFISYSSFQSSFNTDQKSANNGSTVRRSIRSIFRRAAELPRVHMGPLTYSHGINELVNKKLRKDCDLSTLCRVLQRGIRMIRMTRRRRKFYEFKLINNNGQIIWKDGSKYLELDSVKDIRIGDTASTYQEEVDPKRLRSDSKLWIAIIYKVSNKLKALHVVALNELDFNTFLSCICGLVKLRRELMESILLPDNSQFARIHWQITVSEKEEDEKKDTLSFADVKKLCDKFHIYVSTGQLLEFFQLADIN-HNGLLNYFEFEKFIKILKNRKEVNMIWSKFTKPPHSHLSFENFFQFLITEQHEQVDRQTAWSYFIKYREPT-----QLTMGQDGFTKFLKE------QPYLVEVKEELYSKPLNHYFIASSHNTYLLGKQIAETPSVEGYIQVLQQGCRCVEIDIWDGENG-PVVCHG-FLTSAIPLKTVIRVIKKYAFITSPYPLIISLEINCNKDNQKLASLIMREVLAEQLYFVGTRTD---KLPSPRELKHKILLKSKKTSEATRGLSVNEPFPSSFSSSYESANEQELR-----------------------------------------------------------MKDDSTNSSSATN---------SSSMQRIKRIGLKKHADIINDVSNISGIHGIKFR------------NFSLPESKTIAHCFSLNERKVEYMIKDKHLKLS-----------------LDKHNRRYLMRVYPHVLRYKSSNFNPIPFWKAGVQMVATNWQTNDIGQQLNLAMFQILDHQPDGSFKSGYVLKPKKLLPVVTKAKMIPLIYEHFENGSDPVTVKIRILSTQLLPRLNDTSPSRNN--TNSFVKVEFHTDDEPTMPISIDKGTRISATEASTKSSQGNGFNPIWDAEVSITLKDTDLTFIKFMVISEETQ----IASVCLKLNYLRMGYRHIPLFNMEGEQYIFCTLFIHTQIL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . :. * . : . . : . :. :* * :*::: : : .: :::: . : *: * .:. * :... : *: : .. . .: ..: ::*.:*: . .*::: : *: :.. . * :* :* . .: :.: ...**:.:* :* .*::: :. :: ::*: ** : ::* * : ** * *::..*::: :: .::: :.**. .: :** **: . :*: ** : :* ****:: :. :* .*:::: :**.:*:*:******* *.*: . . *: * *** ******:* *** :* *:* ** *** * :* *:..*:**** .. :*:*:*:* :*. :** : : ::* ::: : . :: ****. ** ***:*.** . : : .... *.. . : *. :. ... .* :: *: *: :.: . . : : .:* . *. : : *: :.:* . ::* :.*:: * *:** * .***:** ***:** ::** *:*::. *** * * . .****** : . :. : : :. : ::*:* * **: .*: . .. :.**:**. :*:. .: .*: :.***** *: : : :: .::::::*:* ..:. *.. : :. : ****: * .** . :. . . . ", "identical_positions": 179, "similar_positions": 289, "identity": "11.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101112-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C1T0-1", "uniprot_id": "MMEL1_RAT", "id": "P0C1T0-1", "name": "Membrane metallo-endopeptidase-like 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MGKSESSVGMMERADNCGRRRL-GFVECG------------------LLVLLTLLLMGAIVTLGVFYS--IGKQLPLLNSLLHVSRHERTVVKRVLR---DSSQKSDICTTPSCVIAAARILQNMDQSKK-PCDNFYQYACGGWLRHHVIPETNSRYSVFDILRDELEVILKGVLEDSSVQ----------------------------------------------------------------------------------------------------------------HRPAVEKAKTLYRSCMNQSVIEKRDSEPLLNVLDMIGGWPVAMDKWNETMGPKWELERQLAVLNSQFNRRVLIDLFIWNDDQNSSRHVIYIDQPTLGMPSREYYFKEDS-HRVREAYLQFMTSVATMLRRDLNLPGETDLVQEEMAQVLHLETHLANATVPQEKRHDVTALYHRMGLEELQERFGLKGFNWTLFIQNVLSSVQVELLPNEEVVVYGIPYLENLEEIIDVFPAQTLQNYLVWRLVLDRIGSLSQRFKEARVDYRKALYGTTMEEVRWRECVSYVNS-----------NMESAVGSLYIKRAFSKDSKSIVSELIEKIRSVFVDNLDELN---WMDEESKKKAQEKALNIREQIGYPDYILEDNNRHLDEEYSSLTFSEDLYFENGLQNLKNNAQRSLKKLR-EKVDQNLWIIGA--AVVNAFYSPNRNLIVFPAGILQPPFFSK-DQPQALNFGGIGMVIGHEITHGFDDNGRNFDKNGNMLDWWSNFSARHFRQQSQCMIYQYSNFSWELADNQNVNGFSTLGENIADNGGVRQAYKAYLQWLAEGG------RDQRLPGLNLTYAQLFFINYAQVWCGSYRPEFAIQSIKTDVHSPLNAQVLGSLQNLPGFSEAFHCPRGSPMHPMNRCRIW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLI3-1", "uniprot_id": "MMEL1_MOUSE", "id": "Q9JLI3-1", "name": "Membrane metallo-endopeptidase-like 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MVERAGWCRKKSP-GFVEYG------------------LMVLL-LLLLGAIVTLGVFYS--IGKQLPLLTSLLHFSWDERTVVKRALR---DSSLKSDICTTPSCVIAAARILENMDQSRN-PCENFYQYACGGWLRHHVIPETNSRYSVFDILRDELEVILKGVLEDSTSQ----------------------------------------------------------------------------------------------------------------HRPAVEKAKTLYRSCMNQSVIEKRDSEPLLSVLKMVGGWPVAMDKWNETMGLKWELERQLAVLNSQFNRRVLIDLFIWNDDQNSSRHVIYIDQPTLGMPSREYYFQEDNNHKVRKAYLEFMTSVATMLRKDQNLSKESAMVREEMAEVLELETHLANATVPQEKRHDVTALYHRMDLMELQERFGLKGFNWTLFIQNVLSSVEVELFPDEEVVVYGIPYLENLEDIIDSYSARTMQNYLVWRLVLDRIGSLSQRFKEARVDYRKALYGTTVEEVRWRECVSYVNS-----------NMESAVGSLYIKRAFSKDSKSTVRELIEKIRSVFVDNLDELN---WMDEESKKKAQEKAMNIREQIGYPDYILEDNNKHLDEEYSSLTFYEDLYFENGLQNLKNNAQRSLKKLR-EKVDQNLWIIGA--AVVNAFYSPNRNQIVFPAGILQPPFFSK-DQPQSLNFGGIGMVIGHEITHGFDDNGRNFDKNGNMLDWWSNFSARHFQQQSQCMIYQYGNFSWELADNQNVNGFSTLGENIADNGGVRQAYKAYLRWLADGG------KDQRLPGLNLTYAQLFFINYAQVWCGSYRPEFAVQSIKTDVHSPLKYRVLGSLQNLPGFSEAFHCPRGSPMHPMKRCRIW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q495T6-1", "uniprot_id": "MMEL1_HUMAN", "id": "Q495T6-1", "name": "Membrane metallo-endopeptidase-like 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MGKSEGPVGMVESAGRAGQKRP-GFLEGG------------------LLLLL-LLVTAALVALGVLYADRRGKQLPRLASRLCFLQEERTFVKRKPRGIPEAQEVSEVCTTPGCVIAAARILQNMDPTTE-PCDDFYQFACGGWLRRHVIPETNSRYSIFDVLRDELEVILKAVLENSTAK----------------------------------------------------------------------------------------------------------------DRPAVEKARTLYRSCMNQSVIEKRGSQPLLDILEVVGGWPVAMDRWNETVGLEWELERQLALMNSQFNRRVLIDLFIWNDDQNSSRHIIYIDQPTLGMPSREYYFNGGSNRKVREAYLQFMVSVATLLREDANLPRDSCLVQEDMVQVLELETQLAKATVPQEERHDVIALYHRMGLEELQSQFGLKGFNWTLFIQTVLSSVKIKLLPDEEVVVYGIPYLQNLENIIDTYSARTIQNYLVWRLVLDRIGSLSQRFKDTRVNYRKALFGTMVEEVRWRECVGYVNS-----------NMENAVGSLYVREAFPGDSKSMVRELIDKVRTVFVETLDELG---WMDEESKKKAQEKAMSIREQIGHPDYILEEMNRRLDEEYSNLNFSEDLYFENSLQNLKVGAQRSLRKLR-EKVDPNLWIIGA--AVVNAFYSPNRNQIVFPAGILQPPFFSK-EQPQALNFGGIGMVIGHEITHGFDDNGRNFDKNGNMMDWWSNFSTQHFREQSECMIYQYGNYSWDLADEQNVNGFNTLGENIADNGGVRQAYKAYLKWMAEGG------KDQQLPGLDLTHEQLFFINYAQVWCGSYRPEFAIQSIKTDVHSPLKYRVLGSLQNLAAFADTFHCARGTPMHPKERCRVW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A140LH71-1", "uniprot_id": "A0A140LH71_DANRE", "id": "A0A140LH71-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MGKSESQMDIMEKSTKPRKHRW-TVVEIG------------------LSVIV-LLMSCALAGLIVLYT-------SALRERFNINDSSKGLKYR-------SDADSNVCTTPQCVTAAARLLQNMDPSVD-PCQNFYQYACGGWIERHVIPETSSLHSVFNILRDELEIVLKGVLEMENKD----------------------------------------------------------------------------------------------------------------DREAFKKAKTLYSSCMNEILIEQRDSQPLLRLIDSIGDWPVASEVWNGTSEQTWSLEDTLAVLNGRYNKKAVLEMFVWPDDRDSSRYIIHVDQPALGMPSRDYYLSDGNYKKVREAYLEFMVSMARIAREDRNLTQDEERVLEDMSQVLELETDIANATSPAEERNDITVLYNKMTLREAQQTFNLNGFNWTRYIQGIMSSVSISVQSDEPIVIYCSPYLEKLSEVLSKHSHRTLQNYLVWMLIMDRVSSMSRRFKDVRAHYRKALHGTTVEEARWRDCVRYVQG-----------NMENAVGALYVRETFSGNSKRMVGELIKKIQEAYVETLEELS---WMDEQSKVKAREKAMAISEQIGYPDHILEEENKKLDQEYAHLNFSEENYFENILENLAASAQKGHKKLR-EPVDPDMWIIGA--AVVNAFYSHNRNQIVFPAGILQPPFFSE-KQLQALNFGGIGMVIGHEITHGFDDHGRNFDKDGNMYNWWSNYSAERFEDQSKCMVEQYGRFSWKLAGGQNVSGITTLGENIADNGGVRQAYKAYVKWVEREG------EEPRLPGLDMNHKQLFFLNFAQVWCGACRPEYAIQTIKTDPHSPLEYRVLGSLQNFEAFSEAFHCARGAPMNPEEKCRVW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W436-1", "uniprot_id": "NEP_DROME", "id": "Q9W436-1", "name": "Neprilysin-1", "aln": "-----------------------------------------------------------------------------------MSQQHEATAAAAEKPLNNGYLQANAPLEELSATVVSPLLGQQQVQHQAPHQMQQQQQQQQQNKLPTVVFLAPDGSGGVGIQRGNPAQGNP-GMVTGTGSHSDWLLKESQQRRRLLVLAIAFTVLGAAIGALAIYFAS---VHQRCHLYRLEPDNDDRPNGRWNQDSGSAHEGQDNICMTQECVRTAASLLSAMDLNSD-PCEDFFQYACGTWNKMHPIPEDRSSISTFEVLSDQQQVILRAVLEEPIDER---------------------------------------------------------------------------------------------------------------DNKATIKAKTFFKSCMDIPQIRKIGTGRLKQVLQSLGGWPVIERNWSPPADLS--VERLMGQLRLNYSEPVMIELYVGADDKNSSVNILQMDQLQYALPSRDYYLKESS-ANDRRAYHRYMTQVALLLG------ADPATAAAELEKVVLFETQLVNVSLPEADRHDTSLVYRKMLLPELQELV--PEVQWQEYLQAALG-PGIPLQEDEPLVTYGLHYLTEMGKILAHTDRRVVHNYMLWRLVMSLMSHMIDEYQRERVEFRKILMGIQSERTRWSQCVEWTNK-----------KLGVAVGALFIRDNFNQESKEVALEMIHTIRAAFNELLAEND---WMDDETRAVAKEKADSMNERIGYPELLTN--ATELEQEYVNLTIVPDNFINNVLSILQWESEKMLRLLR-QPVDKEKWTTEP--AVVNAFYNPNKNDIVFPAGILQPLFYSQ-HFPKSLNYGGIGVVIGHEITHGFDDKGRQFDKEGNMMQWWNNATIEAFRERTQCVIDQYSRYKINEVD-MFMDGRMTQGENIADNGGLKQAFRAYKKWETLHG------REQQLPGLNMTHDQLFFLNYAQIWCGSMRPEDALTKIRSAVHSPGFVRVLGPLSNSRDFASAYKCPLGSTMNPAEKCSVW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4K692-1", "uniprot_id": "NEP2_DROME", "id": "A0A0B4K692-1", "name": "Neprilysin-2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------MQTVIQNPNWWRRRNKLEKSLL-VSLG---------------------IMFVVLATGFGLWIGKVLRTS---PPSNPQATALHGDSTTINQVPTGTASKGKSGDSGDVCLTQECIHTASTVLRKMKPEVE-PCDNFYEFACGTYLEEENIPDDKVSISTFSVISDKLQEQLKDIITAERPET---------------------------------------------------------------------------------------------------------------EPKHFRLPNLLYKACMNKTLIETLGPEPITRVAERLGGWPLIKGDSWNADDSWTWQEQVKKFRTAGFSMDYIIDFSIGVDLQNSTKRLIDLDQSSLALSR--EYLVKGFNETLVTAYYKYMVDIAVLFG------ANRDLAKTELLLSLEFEMALANISWPNEKRRNSSELYNLRTPAQLQAAY--PYVQWVDYMNALLP-EGLNVAEDEMINLSVPSFFEDLGKLLAKTPKRVIANYMFWRIHGFSVGFLSEEFRKRQLQYATALSGRQEQEARWKECVDIATSSMDEVCEDDFDSLGISVGSLYVGKHFHKDSKANALEMVNEIRNVFNDILDEVN---WMDAKTKKEAKLKLHSMATHIGYPDEMLD--NEKLAAYYAKLDIDPDKYFESFLGMNIFGTDYSFNKLR-LPVNKTDWVRHARPAIVNAFYSSLENSIQFPAGILQGHFFNA-QRPKYMNFGAIGYVIGHEITHGFDDQGRQFDVKGNLRDWWHPDTQKAYLAKAKCIIEQYGNYTERATG-LNLNGINTQGENIADNGGVKESYIAYRRWAEKHG------PEAKLPGLDYTPEQMFWVAAGQTWCAKYRKESLKMRITTGVHSPSEFRVLGSLSNMKDFAKDFHCPEGSPMNPVQKCEVW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q8T062-1", "uniprot_id": "NEP4_DROME", "id": "Q8T062-1", "name": "Neprilysin-4", "aln": "MSRHSQLKLAMPSVHGAPATAPGSPMNAKARSVKLGLGVNQRTGRVQWCPGLTCCKMLLLLPVVMLPLTLVLILIMRLDGMLAALQLNEQRMRDLRNSHSEVPVYMEDYEALLPEGSTYNDLINEEFILPASKRTQLQILAAERARRCQPYRYGNGESMELEERNTLMKDSRT-SFLPLG-----IPRECLGSGIELDIKPIDEEAYQRQKKRYQDIAPYWLEKIRIRERREAERHAEEASAEISEATAALQSFWNEEGTREGIRMTQAKTMKRYMDNKVD-PCVDFYKYACGNWERLHPIPKDKAGFDTFEMLRESLDLVLRNLLEKNTPVHSAAELRKSPVRNTLFKLNEQGEGEGEADQAAELTAERLRRHIVSKRQLLNRVLVRYKRYTNGTKRKRLIETPRERTKEEEAAPPVVLPKDKTKDKSDNEEQLHVPTDFLKPHQDAQLKAKNLYRSCVNSAVLAKRGLEPLHTLIRELGGWPVLESQWSE----SNFNWQVLAATLRRYNNDILIVQWVGADIKNSEENIVQFDQTGLGLPTREYFLQPSN-AKYLQAYQRYMAEVMHKMG------ASKADAQRVASELVAFETQLAGITAPAEQRLNVTKLYKRMTLDQLQAVVP--EIKWRAYLQSLQD---REVLGTEEVVIYAVEYMSKLVTLLDETDPRTVSNYMMWRFVRHRINNVDDRFDDIKQSFYHALFGREESPQRWKVCIAQVNT-----------NMGMAVGSMFVSRYFDNNSKRDTLRMTHDLQQAFRDILKTTD---WLDDTTKQLAEEKVNAMSLKIGYPDFILN--PSELNSKYAGIEIYPEKYFENTLNVLLHTAKTEQAKLH-ERVNKTNWQTAP--AIVNAYYSRNKNQIMFPAGILQPPFYHR-HFPKSLNFGGIGVVIGHELTHGFDDKGRLFDRNGNIHKWWTDSSIRGFDERARCIIAQYSNYTVEEVG-IVLNGESTQGENIADNGGLRQAFHAYQRWLKEHPSE---VSDEILPGLNMTGPQLFFLNFGQVWCGAMRPEAIRNKLNTAIHSPGRFRVIGTLSNSVDFAREFNCPLGSPMNPQKKCSVW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VCU1-1", "uniprot_id": "Q9VCU1_DROME", "id": "Q9VCU1-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MASQPLG------------------------------LLLGAILFSICAIDAS------------------------------VPHPLAANYSIDILRLAKAAHIKAYMGDEKEQACNNFYNYACANWPRLHPARKSKTRTNYLEELQELYIRKSADMLKSATRG---------------------------------------------------------------------------------------------------------------AENSADRQLKYFYGSCRLQTNDTRSALNTLQNVTDFRGGWPEIR--VASWYQYEYDWLQVVANLKRKLGVDIFIGLEVILDYKEEKMHRLKIGAPQFPMSRR--HYLHPHFEGTREIYERSIENKLKLYFPE----QSEHWRQEVASQVVQIEQQLAKG-LPHNPALTLAQTTRQRTAAEMKTAYG-SYVDVTRYLQLIFN-----DNLYMDLYETPEDYMSNLVDVIRETPKLQLANYTMWKALEALD-----------------IARVPASQRADIWCVQLAQQ-----------FFPHQLESLFHRNYNHMQMINELQSTWSDIKRVFREDLQASERLLWLTLETRQKAITKLEALKLHFRTHD------DNKLIRQMHGLILNMDRFYPNLVSVLQWKTQRGLAKLMTEPVAEDEVHKLP-------HYEIQKNRIQVPITFLQARFFWDPAYPNGLKYATLGVLLARQMLHGFDGVGRRYDAYGYKNNWWDHTSESSYSRRTQCFQEQYAIFVEYKGK--PVQDKDLLRRIVADNGALDIAYRAYQQWLKNAAETPVIYQRERLPLLDHDHNQIFYLGYAQLYCTDYP-----ETVERFDELPEQLRVNTALSNSQQFANAYGCSREEKLNARFKCTLY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : * : * . .* :*:::**. : . . . . :. : : :: . . :: :* : : *.** . .: : * ::. : .. :. . * . : . . : :* :. * . : : .. ::: : :: .: :: : ** .* : . *: . : : ::: : :: .: : * *: :: * * : :: : .* : : : : . : :. * * . .*. .* * .* :** *: : :::. :* ::.::: ****. ** :* * .** : : ::.*. **. : :.. . :****.: :: ** :* ** *: *:*:: .* :* : . * :* .*.* *: : *. ::. :* ::", "identical_positions": 67, "similar_positions": 159, "identity": "6.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101112-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88281-1", "uniprot_id": "MEGF6_RAT", "id": "O88281-1", "name": "Multiple epidermal growth factor-like domains protein 6", "aln": "MPVRAEARAAWR--VVALALLLLPAMPAAS--PPLTPRPLQPSMPHVCAEQKLTLVGHRQPCVQAFSRIVPVWRRTGCAQQAWCIGQERRTVYYMSYRQVYATEARTVFRCCPGWSQKPGQEGCLSDV-----------------------------------DECASANGGCEGPCCNTVGGFYCRCPPGYQLQGDGKTCQDVDECRAHNGGCQHRCVNTPGSYLCECKPGFRLHTDGRTCLAISSCTLGNGGCQHQCVQLTVTQHRCQCRPQYQLQEDGRRCVRRSPCAEGNGGCMHICQELRGLAHCGCHPGYQLAADRKTCEDVDECALGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEAGNGGCSHGCSHTSTGPLCTCPRGYELDEDQKTCIDIDDCAN-SPCCQQACANTPGGYECSCFAGYRLNTDGCGCEDVDECASGHGGCEHHCSNLAGSFQCFCEAGYRLDEDRRGCTSLEESVVDLDGRLPFVRPLPHIAVLRDELPRLFQDDYGAEEEAAAAELRGEHTLTEKFVCLDHSFGHDCSLTCDDCRNGGTCFPGQDGCDCPEGWTGIICNETCPPDTFGKNCSSPCTCQNGGTCDPVLGACRCPPGVSGAHCEDGCPKGFYGKHCRKKCHCANRGRCHRLYGACLCDPGLYGRFCHLACPPWAFGPGCSEDCLCEQSHTRSCNPKDGSCSCKAGFQGERCQAECESGFFGPGCRHRCTCQPGVACDPVSGECRTQCPPGYQGEDCGQECPVGTFGVNCSGSCSCVGAPCHRVTGECLCPPGKTGEDCGADCPEGRWGLGCQEICPACEHGASCNPETGTCLCLPGFVGSRCQDTCSAGWYGTGCQIRCACANDGHCDPTTGRCSCAPGWTGLSCQRACDSGHWGPDCIHPCNCSAGHGNCDAVSGLCLCEAGYEGPRCEQSCRQGYYGPSCEQKCRCEHGAACDHVSGACTCPAGWRGSFCEHACPAGFFGLDCDSACNCSAGAPCDAVTGSCICPAGRWGPRCAQSCPPLTFGLNCSQICTCFNGASCDSVTGQCHCAPGWMGPTCLQACPPGLYGKNCQHSCLCRNGGRCDPILGQCTCPEGWTGLACENECLPGHYAAGCQLNCSCLHGGICDRLTGHCLCPAGWTGDKCQSSCVSGTFGVHCEEHCACRKGASCHHVTGACFCPPGWRGPHCEQACPRGWFGEACAQRCLCPTNASCHHVTGECRCPPGFTGLSCEQACQPGTFGKDCEHLCQCPGETWACDPASGVCTCAAGYHGTGCLQRCPSGRYGPGCEHICKCLNGGTCDPATGACYCPAGFLGADCSLACPQGRFGPSCAHVCACRQGAACDPVSGACICSPGKTGVRCEHGCPQDRFGKGCELKCACRNGGLCHATNGSCSCPLGWMGPHCEHACPAGRYGAACLLECFCQNNGSCEPTTGACLCGPGFYGQACEHSCPSGFHGPGCQRVCECQQGAPCDPVSGQCLCPAGFHGQFCEKGCESGSFGDGCLQQCNCHTGVPCDPISGLCLCPPGRTGAACDLDCRRGRFGPGCALRCDCGGGADCDPISGQCHCVDSYMGPTCR--------EVPTQISSSR---PAPQHPSSR---AMKH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80V70-1", "uniprot_id": "MEGF6_MOUSE", "id": "Q80V70-1", "name": "Multiple epidermal growth factor-like domains protein 6", "aln": "MPVGVEARASWR--VVALTLLLLPAVPAAS--QPLPPRPLQPSMPHVCAEQKLTLVGHRQPCVQAFSRVVPVWR-SGCGQQAWCVGQERRTVYYMSYRQVYATEARTVFRCCPGWSQKPGQEGCLSDV-----------------------------------DECANANGGCEGPCCNTVGGFYCRCPPGYQLQGDGKTCQDVDECRSHNGGCQHRCVNTPGSYLCECKPGFRLHTDGRTCLAISSCTLGNGGCQHQCVQLTVTQHRCQCRPQYQLQEDGRRCVRRSPCADGNGGCMHTCQELRGLAHCGCHPGYQLAADRKACEDVDECALGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEAGNGGCSHGCSHTSTGPLCTCPRGYELDEDQKTCIDIDDCAN-SPCCQQVCANTPGGYECSCFAGYRLNTDGCGCEDVDECASGHSGCEHHCSNLAGSFQCFCEAGYRLDEDRRGCTPLEESVVDLDGQLPFVRPLPHIAVLGDELPQLFQDDYGAEEEAVA-ELRGEHTLTEKFVCLDHSFGHDCSLTCDDCRNGGTCFPGLDGCDCPEGWTGIICNETCPPDTFGKNCSSPCICQNGGTCDPVSGACRCPPGVSGAHCEDGCPKGFYGKHCRKKCHCANRGRCHRLYGACLCDPGLYGRFCHLACPPWAFGPGCSEDCLCEQSHTRSCNSKDGSCSCKAGFQGERCEAECEPGSFGPGCRNRCTCRPGVACDPVSGECRTQCPPGYQGEDCGQECPVGTFGVNCSGSCSCVGAPCHRVTGECLCPPGKTGEDCGADCPEGRWGLGCQEICPACEHGASCDPETGTCLCLPGFVGSRCQDACPAGWFGTGCQMRCACANDGHCHPATGRCSCAPGWTGLSCQRACDSGHWGPDCIHPCNCSAGHGNCDAVSGLCLCEAGYEGPQCEQWCRQGYFGPGCEQKCRCEHGATCDHVSGACTCPAGWRGSFCEHACPAGFFGLDCGSACNCSAGAPCDAVTGSCICPAGRWGPHCAQTCPPLTFGLNCSQICTCFNGASCDPVLGQCHCAPGWMGPTCLQACPAGLYGKNCQHSCLCRNGGSCDPILGQCTCPEGWTGLACENECLPGHHGAGCRLNCSCLNGGTCDRLTGHCRCPAGWTGDKCQSPCVSGMFGVHCEEHCACRKGATCHHVTGACLCPPGWRGSHCEQACPRGWFGEACAQRCHCPPGASCHHVSGECHCPPGFTGPGCEQACQPGTFGKDCEHPCQCPGETWACHPASGACVCAAGYHGTDCQQRCPSGRYGPGCEQICKCLNGGTCDPATGACYCPAGFLGADCSLACPQGRFGPSCAHVCTCGQGAACDPVSGTCICPPGKTGGHCERGCPQDRFGKGCEHKCACRNGGLCHATNGSCSCPLGWMGPHCEHACPAGRYGAACLLECSCQNNGSCEPTSGACLCGPGFYGQACEDTCPAGFHGSGCQRVCECQQGAPCDPVSGRCLCPAGFRGQFCERGCKPGFFGDGCLQQCNSPTGVPCDPISGLCLCPPGRAGTTCDLDCRRGRFGPGCALRCDCGGGADCDPISGQCHCVDSYTGPTCR--------EVPTQLSSIR---PAPQHSSSK---AMKH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75095-1", "uniprot_id": "MEGF6_HUMAN", "id": "O75095-1", "name": "Multiple epidermal growth factor-like domains protein 6", "aln": "MSFLEEARAAGRAVVLALVLLLLPAVPVGASVPPRPLLPLQPGMPHVCAEQELTLVGRRQPCVQALSHTVPVWK-AGCGWQAWCVGHERRTVYYMGYRQVYTTEARTVLRCCRGWMQQPDEEGCLS-------------------------------------AECS-ASLCFHGGRCVPGSAQPCHCPPGFQGP---RCQYDVDECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCAD-SPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEA-ELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLR-------------------------------------------GWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGPLRLPENPSLAQGSAGTLPASSRPTSRSGGPARH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B4A3-1", "uniprot_id": "A0A8M3B4A3_DANRE", "id": "A0A8M3B4A3-1", "name": "", "aln": "---------MKNVDLLLSLIILVDGINAVS----RLGKDLKPHMPNVCAEKEVKLVAQMQPCVQAFTRMVKAWK-QGCQGQSWCVGYERRTAYYTAYRQVYRQEQQTVYKCCPGWSQLNGEAGCLYPVCRSGVCFNGGQCKEGSAQLCVCPAGFSGPSCQYDVNECEETNGGCEALCCNTIGSFYCKCPAGQELKEDGKTCQDIDECQVHNGGCQHTCVNTRGSYHCQCNAGSRLHVDGRTCIAVQSCGVGNGGCEHFCVQQTAGHVQCRCRPDYRLDADGKHCTLVNPCAEQNGGCSQMCHRDGAQARCECHPGYQLAEDGKTCEDIDECALGQTDCAHGCRNTRGSFMCVCSAAYELGVDGKQCYRIEMEIVNSCDHDNGGCSHHCEHSTAGPLCSCNEGYQLDHDHKTCVDINECVDGSSCCEHDCTNYPGGYECYCTAGYRLNTDGCSCDDIDECLAVNGGCDHACLNSAGSFQCSCRRGYRLDEDRRSCILMEESVEALSSGQTVNKPGPGPQLTILQDFDQILEKYEDYEDDTG-ELRAESTLAEKFICLNDSFGVDCSLSCEDCVNGGVCNKHRNACDCPDGWTGVVCNETCPEGWFGRNCSLLCKCKNGGVCDPVSGSCRCPPGVSGELCQDGCPKGLYGKFCNKRCNCANNGRCHRTYGACLCDPGLYGRFCHLPCPKWMFGPGCSEECQCVQQNTIECHRHHGDCICKPGYRGHTCKDECESGFFGSACENKCSCPPGVTCDHVTGACQPKCPAGKTGDKCDQDCVEGRFGIGCSQSCDCSGAPCDKVTGQCTCPAGTFGKRCEKECPEGRWGLGCQEWCPVCENGGRCDRRNGTCVCSPGFIGRLCQNSCPAGRFGVGCQLRCVCDLGVRCNPVSGRCSCPPGWTGHNCRKVCDAGRWGLDCESVCDCRNADGVCDAQTGRCHCEAGFTGARCDQKCPAGSFGPGCKHRCQCENQASCDHVGGACTCKTGWTGTFCEKPCPQGFYGLDCQQKCVCLNGGLCDHVSGQCFCKAGWIGTRCNQTCPAGWFGVSCSQTCVCHNNSSCDAVSGQCECGAGWTGDTCSQRCPAGVFGDGCVHRCLCQNGASCDPESGHCFCPSGWTGAACQLECPAGRFGSDCQDRCECVNGAQCDGQTGRCVCPPGWTGERCENECERGWFGVGCEDRCQCDHGAVCHHVSGQCLCPAGWRGRRCEKACLPGSFGQDCVQRCSCPSGSSCHHVTGHCGCAPGFTGDGCEHSCLPGTFGQDCNQVCQCSERNQLCHPVTGVCYCAPGFTGLKCEQTCPQGLYGSGCEHQCECLNGGVCLSDSGSCQCPAGFIGAQCNQTCPAGRYGLDCAHVSACGTGVRNDPATGRCTAH---------QVCPPGWFGSGCSQRCDCSNRGVCDGVSGNCSCALGWTGKHCDKECPDGSFGPDCSLQCSCQNNSTCDRVTGSCHCRPGYYGHLCEHACPAGLFGSGCQQQCDCMNGASCHPDTGQCVCPAGVHGPRCQHVCAQGRFGVNCSQSCDCADGASCDPVSGRCVCPSGKTGVRCDSDCSVNRFGPDCSLLCECENGAQCDSRNGRCFCLSGWIGFTCS-------QSAPPELNSRRSEEDQLQLNTS--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :: ::*: .: . : *:* **:****:::.**.: ******::: * .*: ** *:**:* ****.** .***** * :** :** ** * .: *** ** :. .. * . .. *:**.* : : *:***: ******* **** *** *:*:.* ***.*.***:*:.** :*****:* *** * : :*:*** ::*: **::*. .***: **.* : *: . *:* ** ***** * *:***:**** * ::***** **:*** *** *.****.**:*************: .****** *.*:::****:* .**:** *::**:*:::*.: *.**:: *:* ****** * *****.:***.*:*:*** : ..**:* * * ****** *. ****.****.* :**.: *.. .. :* * : : : :. :: . ***.* **:***:**:.*** ****:*:** ***.* :.****:****::****** . **:*** * *:***.**.* *:********* *:****** ***.*.*:*:***.***** *****************.** * *******:* * * :* .*. :.*.* **.*::*. *: *** * **..* : *:* **:** *:* * :**.* *:.*.*:* * **:.** **.* ****. ***:* **.* *: * :************ **.*::.. *: ..*:*:* ***:* **: *.** :* .** ** * . :*.*.:*:***.***** .*::.**:*:** ** *:* ..* *** :* * ****: *.:*:* * * :**.*:::*:*:: *:****.***** :** *:***:.** **:**** . * * *. ** *.*.*:* ** *.:* ::**. :* .*** *.*.*.:***.* ***.*..** * :* * **.*::*..* * ***:**. *** *:* **.**:* **: ** . :.*: *::*. ** **:* **.****::*:. * * **: *.*** **..::****:* * *.***** .**::* **:**:** : ***. .. *.*.:*.* **.*: * * * ** * **.***: * ***** * . :*:* **:**:*::*. :** **:* .*:**. * *. **.:* * . : ** . ** **. * * * *:*.. .*.*** *** * **: ** * :*. * *:* *:**.:*: .:*:* * **:**: **..**.*:.*.*** * * :**.*.* :*:*:****.:* *:: * * ** .* * *:. *..***::* *:**.*::*. *: ** .:***.*:* *:* .**:**. .*:*.*:..: * ** . *. .. . :* ", "identical_positions": 757, "similar_positions": 394, "identity": "46.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101115-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZVQ1-1", "uniprot_id": "D3ZVQ1_RAT", "id": "D3ZVQ1-1", "name": "Centrosomal protein of 72 kDa", "aln": "-MAPGQRLVLCEETVRERSGLGPHRDLAELRSLSIPGTYQEKITHLGNSLMHLTALKSLDLSRNSLVSLEGIQYLVSLESLNLYYNCISSLAEVFRLHTLMELQDVDFRLNPVVKNESDYRLFVVHMLPKLRQLDDRPVRESERKASQLHFAPEDSLDS--KENFSATLTVGRPHHLRNRCTETSAKKCLVMDADDEAVLNLIAECEWDLSNPPGNMSSSQKEHDADLHYAQESRHLLSPLSIQHQCGDSARRGHEKKKVTSRG-CPGHSPQDQLCGELPPQHG-LPEACHLHVQHARIASQPDSVDVEDCASSSQKSTLPSQKIVNPLPVPEKYRKRRMPGGRFQVPSDRECLSFLERADVPSSLEDSLSRQDGLEGQSQVALSHSEALEAEERTSHGTSDPRVLSPKLCSAAAPERRSTLEMALLEALLDLIDRCSSGSGSLHGNEAFLAQARQVLSSLQEFTAARDGSALEKEGVGYLSLENKALQSRLTEQHQQYAAAVTKVTTELNNTKRELDTLRQHLDNSLEENDNLKSLLYNVKQEVKHADTSGALSLQITGLQTSMKQLSGEVMELKQHVAHYDKIQELTQMLQESHSSLVSTNEHLLQELSRARAQHRAEVEQMHWSFQELKKTTALAPHRSSRLGGRQSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D3R3-1", "uniprot_id": "CEP72_MOUSE", "id": "Q9D3R3-1", "name": "Centrosomal protein of 72 kDa", "aln": "-MAPGQRLVLCEETVRERSGLGPHRDLAELRSLSIPGTYQEKITHLGNSLMHLTALKSLDLSRNSLVSLEGIQYLVSLESLNLYYNCISSLAEVFRLHTLLELQDVDFRLNPVVKNESDYRLFVVHMLPKLRQLDDRPVRESERKASQLHFAPEDSLNS--KENFSTTLTVGRPHHLRNRCTETSAKKCLVMDADDEAVLNLIAECEWDLSNPPGNMSSSQKEHEADLHYAQESRHLLSPLSIQHQCGDSARRGHEKKKVTSRG-CPGHSPQDQLCGELPLQHG-LPEACHMHVQHARITSQPDSVDVEDCASSAQKSSLSSQKTVNPLPVPEKYRKRRMPGGRFQVPSDRECLSFLERADGPSSLEDSLSRQDGLEGQSQVALSHSEALEAEERTSHGTSDPRVLSPKLCSAAVPERRSTLEVALLEALLDLIDRCSSGSGSLHGNEAFLAQAKHVLSSLQEFTATRDSSALEKEGIGYLSLENKTLQSRLAEQQQQYTATVTKMTAELNNTKRELDTLRQHLDKSLEENSHLKSLLYNVKKEVKTADTSTALTLQITGLQASMKQLSGEVVELKQHVEHYDKIQELTQMLQESHSSLVSTNEHLLQELSRTRAQHRAEVEQMRWSFQEFKKTTALIPHRSSRRGGRQSC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P209-1", "uniprot_id": "CEP72_HUMAN", "id": "Q9P209-1", "name": "Centrosomal protein of 72 kDa", "aln": "MARAGPRLVLSEEAVRAKSGLGPHRDLAELQSLSIPGTYQEKITHLGHSLMSLTGLKSLDLSRNSLVSLEGIQYLTALESLNLYYNCISSLAEVFRLHALTELVDVDFRLNPVVKVEPDYRLFVVHLLPKLQQLDDRPVRASERKASRLHFASEDSLDS--KESVPASLKEGRPHHPRAKCTEALAKQSLVMDADDEAVLNLIAECEWDLGRPPGSTSFSQKGREADSRGSQESRHLLSPQLVQYQCGDSGKQGRETRRSSCRGCCLEKMPWSQLCGELPPLYGAEPEASRAPRPHTYFTPHPDSMDTEDSASS-QKLDLSGEMVPGPLPAPGKCRKRRMPVGRFQTFSDQEGLGCPERTHGSSVPKESLSRQDSSESRNGRTLSQPEASETEEQRSRGVTDTREPSPGSHS-ALPGKKTALQAALLETLLDLVDRSWGGCRSLHSNEAFLAQARHILSSVEEFTAAQDSSAMVGEDVGSLALESKSLQSRLAEQQQQHAREMSEVTAELHHTHKELDDLRQHLDKSLEENSRLKSLLLSMKKEVKSADTAATLNLQIAGLQTSVKRLCGEIVELKQHLEHYDKIQELTQMLQESHSSLVSTNEHLLQELSQVRAQHRAEVEQMHWSYQELKKTMALFPHSSASHGGCQAC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q501X2-1", "uniprot_id": "CEP72_DANRE", "id": "Q501X2-1", "name": "Centrosomal protein of 72 kDa", "aln": "--MAVDGLPITEQWIREKLNL-QHRCLADVRSLTLPGTYEGKICHLGTSLKNFVRLKSLDLSYNALVTVQGIEHLELLERLNLYYNRLASLQDIFSLHKLQNLKELDLRLNPVVKKHPHYRLYLVHAIPKLRRLDDCPVRDRERKAALMHFSSEENLDSDYKKQVFIQDTTARSSDLRIKAMQKMVKTLSLLEGNEELALNDSSRKTGKRRSLQTLSVRCENECSPLLAHENPSESDIVYLFNDSDCRRSSKHKQES------------------------------------------APSKSSDYKNDARAGPHRVRFVSPVILRHSSVRGESVFTAHPDSHKQPHSHENDCSSPKWQN------QLLDRANLVLHPPRLTYSTAETKDRSTKTLKGTYRKP----------------------MELLLSMMEDLWSEKKENQQNRTFLMKMVQILSMMEQEVSGGE------QEIQTLKAALKASIAQADVQEKQHQSEIEELTLQQQQAHESIKRLNEQTKSLLEENVSLQKQLIRAEHKLLASRLKNIPHTQDRGVQSVPEEFN------TKRDIIADDEDGGVGEQQQSYRSLIARNERLLQQLEEALMSK----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * : *: :* : .* ** **:::**::****: ** *** ** :. ******* *:**:::**::* ** ****** ::** ::* ** * :* ::*:******* ...***::** :***::*** *** ****: :**:.*:.*:* *:.. . .*. . * :. : .* :::.::* .** :. . .:: .. : *. : : :* *.:: :*. :. .* :*. :. :: : . .. : * .: * *..: . : . : *.* : : * .*: : . : :*. :* **.::: . . : *.:** : ::** ::: .: : : : * *: :: *.:*: : ::* : ::::..:. *.:: .. **** *:. * :::: : * *:*: :.: .:: *. : . *:*: **:: **:***:*... .: ", "identical_positions": 135, "similar_positions": 185, "identity": "20.74%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101115-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UBK8-2", "uniprot_id": "MTRR_HUMAN", "id": "Q9UBK8-2", "name": "Methionine synthase reductase", "aln": "-----MRRFLLLYATQQGQAKAIAEEICEQAVVHGFSADLHCISESDKYDLKTETAPLVVVVSTTGTGDPPDTARKFVKEIQNQTLPVDFFAHLRYGLLGLGDSEYTYFCNGGKIIDKRLQELGARHFYDTGHADDCVGLELVVEPWIAGLWPALRKHFRSSRGQEEISGALPVASPASSRTDLVKSELLHIESQVELLRFDDSGRKDSEVLKQNAVNSNQSNVVIEDFESSLTRSVPPLSQASLNIPGLPPEYLQVHLQESLGQEESQVSVTSADPVFQVPISKAVQLTTNDAIKTTLLVELDIS-NTDFSYQPGDAFSVICPNSDSEVQSLLQRLQLEDKREHCVLLKIKADTKKKGATLPQHIPAGCSLQFIFTWCLEIRAIPKKAFLRALVDYTSDSAEKRRLQELCSKQGAADYSRFVRDACACLLDLLLAFPSCQPPLSLLLEHLPKLQPRPYSCASSSLFHPGKLHFVFNIVEFLSTATTEVLRKGVCTGWLALLVASVLQPN-IHASHEDSGKALAPKISISPRTTNSFHLPDDPSIPIIMVGPGTGIAPFIGFLQHREKLQEQHPDGNFGAMWLFFGCRHKDRDYLFRKELRHFLKHGILTHLKVSFSRDAPVGEEEAP-AKYVQDNIQLHGQQVARILLQENGHIYVCGDAKNMAKDVHDALVQIISKEVGVEKLEAMKTLATLKEEKRYLQDIWS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C1A3-1", "uniprot_id": "MTRR_MOUSE", "id": "Q8C1A3-1", "name": "Methionine synthase reductase", "aln": "-----MRRFLLLYATQRGQAKAIAEEISEQAVSHGFSADLHCISESEKYDLKTETGPLVMVVSTTGTGDPPDTARKFVKEIHNKTLPTDYFAHLRYGLLGLGDSEYTYFCNGGKVIDKRLQELGAQRFYDTGHADDCVGLELVVEPWIDGLWAALTKHFKSLGGQENMSDTLSRASDAP-LSTAMKPELLHIQSQVELLRLEDVGERDSELREQNETNRGQ-QGRIEDFDSSLVHSVPPLSQSSLSIPAVPPEYLEVHLQESLGQEENQASVPSGDPSFQVPISKAIRLTTNDAVKSTLLLELDIS-KIEFSHQPGDSFNVTCPNSDREVEELLQRLQLADKRAHRVILKIKTDTKKKGAALPAHVPEGRSLQFILTWCLEIRAVPKKAFLRALAEHTSSATEKRRLQELCSKQGAADYNRFIRDASVCLLDLLLTFPSCQPPLSLLLEHLPKLQPRPYSCASSSLRHPDKLHFVFNIVEFPPSTTAASPRKGVCTGWLATLVAPFLQPN-TDVSNADSGDTLAPEIRISPRATNAFHLPEDPSAPIIMVGPGTGVAPFVGFLQHREKLQEQHPDGKFGAMWLFFGCRHKDRDYLFREELRHFLKTGVLTHLKVSFSRDAAPDGEEAP-AKYVQDNLQRHSQQVARTLLQENGYIYVCGDAKNMAKDVNDTLIGIISNEAGVDKLEAMKTLATLKQEKRYLQDIWS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1RE28-1", "uniprot_id": "F1RE28_DANRE", "id": "F1RE28-1", "name": "Methionine synthase reductase", "aln": "MPCEAAAHFLILYGSQRGQAQSIAEEICQQAAEHGFTADISCLSKHDKYNLDSESRPVVFVVSTTGDGDPPDTALKFVRKIKNKSLPHDHLSHLRYALLGLGDTNYANFCNGGKTIDSYLQKLGAKHFYATGHADDGTGLEVVVDPWIEGLWDALKKAFSTMSTSD--QQTLSDCTQDSNHQNASD-QKKNLEVDLQLLKLS---EVDSPKGKTVTSDSIATEIGSTSSVASLKESVPPLSESVLNVPALPPSYLEILLVGTENVEET--VLPDKDGYFEVPISKAVQLTQDDAVKTAILLELDISQQQEQVYQPGDAFDILCPNRDSEVEELLLKLDLQMQKNCTVQVNLLKNTSKKAAKVPLHIPQNGSLQFILTWCLEIRSTPKKAFLRALVDFTQNASEKRRLLELCSKQGSADYNSFVRDSSVCVLDLLRAFPSCCPPLSLLFEHLPKLQPRAYSAASSSLQHPGKVHLVFNVVEFPARPEHP-ARKGLCTGWLVDHVSSILEPHGTALASERPGTSALPKVHVRARPSSTFHLPSDPCVPVVMVGPGTGVAPFIGFLQQREKEREANQEATFGEMWLFFGCRHKDKDFLFREELEKFVHNGTLSHLIVCFSRDEPDAAETVNRPTYVQHNLILHAKNLAKILLEDKGCLYVCGDAKNMAKDVNDTLLEIIGNELQLDKLDAMKIVAGLREDKRYLQDIWS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**:**.:*:***::*****.:**. ***:**: *:*: :**:*.:*: *:*.****** ******* ***::*:*::** *.::****.******::*: ****** **. **:***::** ****** .***:**:*** *** ** * * : .: . :*. .: . . : ::: :::**::. . ** : : : . :** .******:: *.:*.:**.**:: * : . **. :.. * *:******::** :**:*:::*:***** : : :****:*.: *** * **:.** :*:* :: * ::: :*.**.* :* *:* . *****:*******: *********.:.*..::***** *******:***. *:**:..*:**** :**** ******:*********.**.***** **.*:*:***:*** . . ***:*****. *:..*:*: : .* : *:: : .*.:.:****.**. *::*******:***:****:*** :* : :..** ***********:*:***:**.:*:: * *:** *.**** . * . ..***.*: *.:::*: **:::* :*************:*:*: **.:* ::**:*** :* *:::*********", "identical_positions": 353, "similar_positions": 204, "identity": "50.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101117-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VDZ4-1", "uniprot_id": "ZDHC5_MOUSE", "id": "Q8VDZ4-1", "name": "Palmitoyltransferase ZDHHC5", "aln": "MPA-----------ESGKRFKPSK---------------------------YVPVSAAAIFLVG----------------------ATTLFFAFTCPGLSLNVS--PAVPIYNAIMFLFVLANFSMATFMDPGIFPRAEEDEDKEDDFRAP-------LYKTVEIKGIQVRMKWCATCRFYRPPRCSHCSVCDNCVEEFDHHCPWVNNCIGRRNYRYFFLFLLSLTAHIMGVFGFGLLYVLYHIEELSGVRTAVTMAVMCVAGLFFIPVAGLTGFHVVLVARGRTTNEQVTGKFRGGVNPFTNGCCNNVSRVLCSSPAPRYLGRPKKE-KTIVIRPPFLRPEVSD------------------------------GQITVKIMDNGIQGELRRTKSKGSLEITESQS--------------------------ADAEPPPP-------PKPDLSRYTGLRTHLSLATNEDSS--------LLGKDSPPTPTMYKYRP-------------GYSSSSTS------------------------AAMPHSSSAKLSRGDSLKEPTSIADSSR-----------HPSYRSEPSLEP----------ESFRS--------PTFG----KSFHFDPLSSGSR--SSSLKS----------------------------------AQGTGFELGQLQSIRSEGTTSTSYKSLANQTRNGS--------LSYDSLLTPSD----------------------------SPDFESVQAGPEPDPPLGYTSPFLSARLAQQREAERHPRLLPTGPPHREPSPVRYDNLSRHIVASLQEREKLLRQSPPLAGREEEPGLGDSGIQSTPGSGHAPRTSSSSDDSKRSPLSKTPLGRPAVPRFGKPDGLRSRGLGSPEPGTTAPY--LGRSISYSS-QKAPSGVSETEEVALQPLLTPKDEVQLKTTYSKSNGQPKSIGSASP-------GPGQPPLSSPTRGGVKKVSGVGGTTYEISV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2THW7-1", "uniprot_id": "ZDHC5_RAT", "id": "Q2THW7-1", "name": "Palmitoyltransferase ZDHHC5", "aln": "MPA-----------ESGKRFKPSK---------------------------YVPVSAAAIFLVG----------------------ATTLFFAFTCPGLSLDVS--PAVPIYNAIMFLFVLANFSMATFMDPGIFPRAEEDEDKEDDFRAP-------LYKTVEIKGIQVRMKWCATCRFYRPPRCSHCSVCDNCVEEFDHHCPWVNNCIGRRNYRYFFLFLLSLTAHIMGVFGFGLLYVLCHIEELSGVRTAVTMAVMCVAGLFFIPVAGLTGFHVVLVARGRTTNEQVTGKFRGGVNPFTNGCCNNVSRVLCSSPAPRYLGRPKKE-KTIVIRPPFLRPEVSD------------------------------GQITVKIMDNGIQGELRRTKSKGSLEITESQS--------------------------ADAEPPPP-------PKPDLSRYTGLRTHLSLATNEDSS--------LLGKDSPPTPTMYKYRP-------------GYSSSSTS------------------------AAMPHSSSAKLSRGDSLKEPTSIADSSR-----------HPSYRSEPSLEP----------ESFRS--------PTFG----KSFHFDPLSSGSR--SSSLKS----------------------------------AQGTGFELGQLQSIRSEGTTSTSYKSLANQTRNGS--------LSYDSLLTPSD----------------------------SPDFESVQAGPEPDPPLGYTSPFLSARLAQQREAERHPRLLPTGPPHREPSPVRYDNLSRHIVASLQEREKLLRQSPPLAGREEEPGLGDSGIQSTPGSGHAPRTSSSSDDSKRSPLSKTPLGRPAVPRFGKPDGLRGRGLGSPEPGTTAPY--LGRSMSYSS-QKAPSGVSETEEVALQPLLTPKDEVQLKTTYSKSNGQPKSIGSASP-------GPGQPPLSSPTRGGVKKVSGVGGTTYEISV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9C0B5-1", "uniprot_id": "ZDHC5_HUMAN", "id": "Q9C0B5-1", "name": "Palmitoyltransferase ZDHHC5", "aln": "MPA-----------ESGKRFKPSK---------------------------YVPVSAAAIFLVG----------------------ATTLFFAFTCPGLSLYVS--PAVPIYNAIMFLFVLANFSMATFMDPGIFPRAEEDEDKEDDFRAP-------LYKTVEIKGIQVRMKWCATCRFYRPPRCSHCSVCDNCVEEFDHHCPWVNNCIGRRNYRYFFLFLLSLTAHIMGVFGFGLLYVLYHIEELSGVRTAVTMAVMCVAGLFFIPVAGLTGFHVVLVARGRTTNEQVTGKFRGGVNPFTNGCCNNVSRVLCSSPAPRYLGRPKKE-KTIVIRPPFLRPEVSD------------------------------GQITVKIMDNGIQGELRRTKSKGSLEITESQS--------------------------ADAEPPPP-------PKPDLSRYTGLRTHLGLATNEDSS--------LLAKDSPPTPTMYKYRP-------------GYSSSSTS------------------------AAMPHSSSAKLSRGDSLKEPTSIAESSR-----------HPSYRSEPSLEP----------ESFRS--------PTFG----KSFHFDPLSSGSR--SSSLKS----------------------------------AQGTGFELGQLQSIRSEGTTSTSYKSLANQTRNGS--------LSYDSLLTPSD----------------------------SPDFESVQAGPEPDPPLGYTSPFLSARLAQQREAERHPRLVPTGPTHREPSPVRYDNLSRHIVASLQEREKLLRQSPPLPGREEEPGLGDSGIQSTPGSGHAPRTSSSSDDSKRSPLGKTPLGRPAVPRFGKPDGLRGRGVGSPEPGPTAPY--LGRSMSYSS-QKAQPGVSETEEVALQPLLTPKDEVQLKTTYSKSNGQPKSLGSASP-------GPGQPPLSSPTRGGVKKVSGVGGTTYEISV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FBS9-1", "uniprot_id": "DHC5B_DANRE", "id": "E7FBS9-1", "name": "Palmitoyltransferase ZDHHC5-B", "aln": "MPVGLSVGGALGDPSPSRPFRPSR---------------------------YVPVSAATAFLVG----------------------ATTLFLCFTCPWLSEKFS--SFIPLYNVVVFLFTLANFCMATFMDPGVFPRAEEDEDKEDDFRAP-------LYKTVEVRGIQVRMKWCSTCRFYRPPRCSHCSVCDNCVEEFDHHCPWVNNCIGRRNYRYFFLFLLSLTVHIMDVFGFSLLYILHHTKQLDLVQSGVTMAVMCVAGLFFVPVAGLTGFHVVLVARGRTTNEQVTGKFRGGVNPFTHGCFKNIAHVLCSSQAPRYLGRLRKP-QSVQVQPPFLRPPLSE------------------------------AQLAAKVLDNGIQ------QSKSSLEIMESQS--------------------------TDADPPPP-------PKPE-HRYPGLPHTQ----NEECS--------LLT-EAPPTPSLYKYRP-------------AYSSPGKN------------------------HTAS-THSSKMSRGNSMTESPSVPVTTG-----------QPSYRSDPSLSSRGAAGCRGGAEGGRSGSGGLGGASAFGGRSYPSFTDTLLQSAAASCSSSLRS----------------------------------AHTAHNALG---PLISEGTTSTSYKSLANQTRNGS--------LSYESLLTPSE----------------------------SPEFES--AAHELSPPRPHPPHSLST------AAGAAPILGYTSP-----------------FLSAQQREGSLQACP-------------APLRPSPNRAFLRPISSPP--SRAPPLSP-----------------RARSLGSPPPGPAPGHTPLGKSMSYGGGAELQHRPSSSGGGTSMPNSTIKQNVANHNTHS----------------------------HKPARG-VKKVSGVGGTTYEISV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W345-1", "uniprot_id": "ZDHC8_DROME", "id": "Q9W345-1", "name": "Palmitoyltransferase ZDHHC8", "aln": "---------------MPKCDVKTR---------------------------YIPATFAWIVLLL----------------------TTFLFFFYPCQ-FYVKSH--PWVLAYQGVITFFVLANFTLATFMDPGIIPKASPDEDCEEELRAP-------LYKNAEINGITVKMKWCVTCKFYRPPRCSHCSVCNHCIETFDHHCPWVNNCIGRRNYRFFFFFLVSLSIHMLSIFSLCLVYVLKIMPNIKDTAPIVAIILMGLVTILAIPIFGLTGFHMVLVSRGRTTNEQVTGKFKGGYNPFSRGCWHNCCYTQFGPQYPSLLNPKKYASRRSQVQNQAISTICNDRSGQQTGAGSGAGGNGTAAVSGGGGGVGSGGGMRGTAVQYSPRSFYDASREKRGIQVKTYMAEGNGYNQRSGSTTLYSKLSPGRECSDTDLEPPPASQSQDCEPTPPLQRHNSSSFYLPQVSDSGGLNGSVSTGGGGGGDSPRHMRLYHPRHSPHARPRGLDPQRGYTSDALSPDHPVGYGVGVNGSQQQQQQALAAAAAAAAVAAQNQRSATTTATPTMQQRIKPLGVATPLVMASPVRRSNPGTPTQPRRPDFIGLNAQAVAQQQQQQQQAAAAAAAAYYEYTSGLPPQHPQAPSIQQQQQQLLLQQQRVLMQHQQQQQALQQQQQQQQQAAVHAAHPQHAALAQAAYGGSPQRRFLSEGELVRQGAGGGVAGGELSYARSNNTVDNIRELAGSPQRGVYMWKDTSPGFTNNAGQQQQQQQQAQQVVSSGIGSSAGTLSSSGAAAGVMPHAQYMTAGGGAHPLIMTHSRLQDYTIQQQQQQQQQQAAAAAAASYHRSNPTSPTTMPQVSGAGQSYILRYGGGGAVGAAGSSGSLASVTASNPATGGGGYQPALRGGVAVFPPNPMGNQGGGNLQTQPSPQIKRKQTPTRPMSFVRALEMADSMEMQSLEQQQNGGIPGSGSVGNNQQAGGGGGGHLMQSNASNSGTPDRASIYDMNYEISV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06551-1", "uniprot_id": "ERFB_YEAST", "id": "Q06551-1", "name": "Palmitoyltransferase ERF2", "aln": "MALVSRRSTRSESTSITKEEHTGEGSLTKLFFRWLVTLEGDQDINDGKGYISLPNVSNYIFFLGGRFRTVKGAKPLWLGVLLAIVCPMVLFSIFEAHKLWHTQNGYKVLVIFFYYFWVITLASFIRTATSDPGVLPRNIHLSQLRNNYQIPQEYYNLITLPTHSSISKDITIKYCPSCRIWRPPRSSHCSTCNVCVMVHDHHCIWVNNCIGKRNYRFFLIFLLGAILSSVILLTNCAIHIARESGGPRDCP--VAILLLCYAGLTLWYPAILFTYHIFMAG-----NQQTTREFLKGIGSKKNPVFHRVVKEENIYNKGSFLKN-----------------------------------------------------MGHLMLE------------------------------------------------------------------------------------------------------PRGPSFVSARKP--------------------------------------------HEAGDWRFMDLSPAHSFEKIQKI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :* .:: . ** : . : : : . .:.**.* :: ***::*: .: .:: : * . . . : :*:* :*:::****.****.*: *: .**** *******:****:*::**:. : :: ::: *:: :: . : * :*:.:.. *:*.* :* * .. .. :. * : :: * : * . . . : .: ", "identical_positions": 53, "similar_positions": 86, "identity": "5.26%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101124-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96NB1-1", "uniprot_id": "CEP20_HUMAN", "id": "Q96NB1-1", "name": "Centrosomal protein 20", "aln": "MATVAELKAVLKDTLEKKGVLGHLKARIRAEVFNALDDDREPRPSLSHENLLINELIREYLEFNKYKYTASVLIAESGQPVVPLDRQFLIHELNAFEESKDNTIPLLYGILAHFLRGTKDGIQNAFLKGPSLQPSDPSLGRQPSRRKPMDDHLRKEEQKSTNIEDLHVS-QAVNR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CZS3-1", "uniprot_id": "CEP20_MOUSE", "id": "Q9CZS3-1", "name": "Centrosomal protein 20", "aln": "MATVTELKAVLKDTLEKRGVLGHLKARIRAEVFNALDDDREPRPSLSHENLLINELIREYLEFNKYKYTASVLIAESGQPVVPLDRQFLIRELNAFEESKDNSIPLLYGILAHFLRGPPDGAQNVLLTESTLHPATKHLSWKPSRR-PDDDHVRKDTGPRTTTEELPAAAQAVSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "I3ITH9-1", "uniprot_id": "I3ITH9_DANRE", "id": "I3ITH9-1", "name": "Centrosomal protein 20", "aln": "MATITELKSALRETLEARGVLGQLKARVRAEVFSALDDPNTPRPPLSHDNLLINELIREYLEFNKYRYTASVLTAESGQPEVPLDRDFLAKELNVAEDSSARSVPLLYGLFHHFLSSKEEHKGQIFLKGSATVTSQ-------------EPHGHRDAES----------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***::***:.*::*** :****:****:*****.**** . ***.***:*****************:****** ****** *****:** :***. *:*. .::*****:: *** . : : :*. .: .: : * ::: ", "identical_positions": 84, "similar_positions": 37, "identity": "48.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101124-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08638-1", "uniprot_id": "MYH11_MOUSE", "id": "O08638-1", "name": "Myosin-11", "aln": "----------------------------------------------MAQKGQLSDDEKFLFVDKNFMNSPMAQADWVAKKLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKYLPIYSEKIVDMYKGKK------------RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTQKVIQYLAVVASSHKGKK----DSSIT-----------------------------------------GELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYLLAGAKEKMKSDLLLES--FNSYTFLSNGF-VPIPAAQDDEMFQETLEAMSIMGFNEEEQLAILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLVGINVTDFTRAILTPRIKVGRDVVQKAQTKEQADFAIEALAKATYERLFRWILSRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPSIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCSEQGNHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTES--SLPSASKTKKGMFRTVGQLYKEQLGKLMATLRNTTANFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAAN------AIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFTKRQQQLTAMKVIQRNCAAYLKLRN-WQWWRLFTKVKPLLQVTRQEEEMQAKEEEMQKITERQQKAETELKELEQKHTQLAEEKTLLQEQLQAETELYAESEEMRVRLAAKKQELEEILHEMEARLEEEEDRRQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDDILVMDDQNSKLSKERKLLEERVSDLTTNLAEEEEKAKNLTKLKSKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDEEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHTQAVEELTEQLEQFKRAKANLDKSKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEVQLQDLQSKCSDGERARAELSDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLGSQLQDTQELLQEETRQKLNVSTKLRQLEDERNSLQDQLDEEMEAKQNLERHVSTLNIQLSDSKKKLQDFASTIEVMEEGKKRLQKEMEGLSQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQKKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEESEDDVQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELDDARASRDEIFATSKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNTLQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATLQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLQEVEGAVKAKLKSTVAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEVLLQVEDERKMAEQYKEQAEKGNTKVKQLKRQLEEAEEESQCINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNEASF-VPSRRAGG-------RRVIENTDGSEE----------EMDARDSDFNGTKASE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35749-1", "uniprot_id": "MYH11_HUMAN", "id": "P35749-1", "name": "Myosin-11", "aln": "----------------------------------------------MAQKGQLSDDEKFLFVDKNFINSPVAQADWAAKRLVWVPSEKQGFEAASIKEEKGDEVVVELVENGKKVTVGKDDIQKMNPPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVDMYKGKK------------RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK----DTSIT-----------------------------------------GELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEG--FNNYTFLSNGF-VPIPAAQDDEMFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTES--SLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAAN------AIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAAYLKLRN-WQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNETSF-VPSRRSGG-------RRVIENADGSEE----------ETDTRDADFNGTKASE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63862-1", "uniprot_id": "MYH11_RAT", "id": "Q63862-1", "name": "Myosin-11", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KK------------RHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKK----DSSITQ----------------------------------GPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGANIETYLLEKSRAIRHARDERTFHIFYYLIAGAKEKMRNDLLLES--FNSYTFLSNGF-VPIPAAQDDEMFQETLEAMSIMGFSEEEQLAILKVVSSVLQLGNIVFKKERNTDQASMPDNTAAQKVCHLVGINVTDFTRAILTPRIKVGRDVVQKAQTKEQADFAIEALAKATYERLFRWILSRVNKALDKTHRQGASFLGILDIAGFEIFEVNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCSEQGNHPKFQKPKQLKDKTEFSIIHYAGKVDYNASAWLTKNMDPLNDNVTSLLNASSDKFVADLWKDVDRIVGLDQMAKMTES--SLPSASKTKKGMFRTVGQLYKEQLGKLMTTLRNTTPNFVRCIIPNHEKRSGKLDAFLVLEQLRCNGVLEGIRICRQGFPNRIVFQEFRQRYEILAAN------AIPKGFMDGKQACILMIKALELDPNLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFTKRQQQLTASKVIQRNCAAYLKLRN-WQWWRLFTKVKP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDEEMEAKQNLERHVSTLNIQLSDSKKKLQDLASTIEVMEEGKKRLQKEMEGLGQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQKKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMRTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAVKGREEAIKQLRKLQAQMKDFQRELDDARASRDEIFATSKENEKKAKSLEAELMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNTLQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATLQAEQLSNELVTERSAAQKNESARQQLERQNKELRSKLQEVEGAVKAKLKSTVAALEAKIVQLEEQIEQEAREKQAATKLLKQKDKKLKEVLLQVEDERKMVEQYKEQAEKGNTKVKQLKRQLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLRRGNEASF-VPSRRAGG-------RRVIENTDGSEE----------EMDARDSDFNGTKASE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M6Z539-1", "uniprot_id": "A0A8M6Z539_DANRE", "id": "A0A8M6Z539-1", "name": "", "aln": "-----------------------------------------------MTMQDNDDSNKFLFLDSEFKNSGVAQADWSTRKMVWIPSERDGFQSASIKEETGNEVVVELD-NGQKVTVSKDDIQKMNPPKFNKVEDMAALTCLNEASVLHNLRERYFSGLIYTYSGLFCVVINPYKMLPIYSEKIIEMYKGKK------------RHEVPPHIYSVTDNAYRNMLQEREDQSILCTGESGAGKTENTKKVIQYLAVVASSHKGKKEATSDTSSSAPNKQQK----------------------------GSQLAFGELEKQLLQANPILEAFGNAKTIKNDNSSRFGKFIKINFDNTGYIVGANIETYLLEKSRCIRQAKIERSFHIFYYMVAGAKDKMREELLLED--FANYRFLVAGH-VQVQNQQDDEMLEETLEAMEVLGFNEEERIGMFKICSTVLQLGNIEFKAEKNQEQASMPDNTAAQKVCHLQGINVTDFTKAMLTPKIKVGRELVQKAQTKEQADFAVEALAKAMYDRLFRWILGRVNKALDKTKRQGASFIGILDIAGFEIFEDNSFEQLCINYTNEKLQQLFNHTMFILEQEEYKKEGIEWSFIDFGLDLQPCIELIERPNNPPGILALLDEECWFPKATDVSFVEKLTNTHSSHCKFSKPKNLKEKTFFTVQHYAGKVDYNAMSWLTKNMDPLNDNVTALLSNSSSAFIQDIWKDVDRVVGLETMAKMAKSDSSAPAASKSKKGMFRTVGQLYKESLGKLMTTLHNTQPNFVRCIIPNHEKRAGKIDAHLVLDQLSCNGVLEGIRICRQGFPNRIVFHEFRQRYEVLAAG------SIPKGFMDGKQSCTLMIKHLDLDPNLYRIGLSKIFFRTGVLAQLEEERDLKLTDIIIAFQAQARGFLGRKAFSNKQKQLTAMKVLQRNCAVYLTLRN-WQWWRLFTKVKPLLQVTRQEEEMNQIEEELQKAKEIAQKSETELKEITQKHDQVVEERNKLQAKLQEEAELYAESEEVRIRLETKKQELEEVLHEMEARLEEEEERSQAFQQEKGNLQQKLKELENHLAEQDATRQKLQLESGAADGKIKKLEEDVLIMEDQKNKLQKEKQQLEERLADFSSNLAEEEEKSKNLTKLKAKHESMISDLEVRMKKEEKSRQDVEKAKRKLETEHSDLQEQMKNLQTLIAELKTQQARSEMEIQELQASVEAESTQKSNALKKIHEMEGLLSELQDELEAEQGAGRKSEKARKELEEELSALRTELEDSLDTTAVQQELRAKREQEVAMLKKLIEDEGRSHEAQVHELKQKHAQAVDELSQQLDQSKRAKATLEKAKQALEKEVGDLNGNLRSLGNAKQDLEQKKKKVETQLADLQTRFNESERKREELGDAVSKLNTEYNNVNSILNEAESKNIKLSKDVVSLNSQLQDAQELLAEETRQKLNFSTRLRQMEDERNGLLEQIDEETEARRNVERHVSSLNTQLSEAKKRLDEYSSNFQMLEESKKRLQRDLEATKGELEEKTASYDKSEKTKNHLQQELDDVLLDLDNQRQLVSNMEKKQRKFDQMLADEKTLSSKYSQERDCAEAEAREKETKCLALTRALEECQGSLRELEKLNKTLRTDMEDLISSKD--NKNAHELEKTKRALEAQVEEMTIQMEELEDELQAAEDAKLHLEVNMQALKVQIQRDIQGREEQSEEKRKQLLKQVRELEAELEDEQKMRTSLAAAKKKLEGDLQDLEDQVDVNSRARDEAVKQLRKIQTQMKDYQRELEDARASHKEVLSDARESERKARAMEAEILHLHEELASAEKARKHAERERDEIAGEMASGSFGKSGTSDEKRRLESKIQHLEEELDDEQATTETLNERLRRSVQEVDQLTNELHTERSNAQRMESGWQQMERQNKELRAKLLEMEGQVKSKQRSTVAALESKLQQTEDQLDHESRERQAIAKAMRQKDKKLKELMNQVEDERKQMEQYKDQAEKANLRARQLKMQMEESDEESQRATAARRKLQKELNEAIEANDALSREVSSLRSKLRRGSDSSFSTPLRRSAGGSFRQARRTMMETSEIPEDGGPSATSVCQPGELQMESISNTQDNN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q99323-3", "uniprot_id": "MYSN_DROME", "id": "Q99323-3", "name": "Myosin heavy chain, non-muscle", "aln": "MKSAWLALKSKSALHPKSEYPVSNIHYPKAANYRQTRNYLEIAAKMSEEVDRNDPELKYLSVERNQFNDPATQAEWTQKRLVWVPHENQGFVAASIKREHGDEVEVELAETGKRVMILRDDIQKMNPPKFDKVEDMAELTCLNEASVLHNIKDRYYSGLIYTYSGLFCVVVNPYKKLPIYTEKIMERYKGIK------------RHEVPPHVFAITDSAYRNMLGDREDQSILCTGESGAGKTENTKKVIQFLAYVAASKPKGSGAVPHPAVLINFSVNTNKYIKVKIMAQNQNQTIEVVNGLKMVEVNSNCQEGELEQQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDASGFISGANIETYLLEKSRAIRQAKDERTFHIFYQLLAGATPEQREKFILDD--VKSYAFLSNGS-LPVPGVDDYAEFQATVKSMNIMGMTSEDFNSIFRIVSAVLLFGSMKFRQERNNDQATLPDNTVAQKIAHLLGLSVTDMTRAFLTPRIKVGRDFVTKAQTKEQVEFAVEAIAKACYERMFKWLVNRINRSLDRTKRQGASFIGILDMAGFEIFELNSFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWKFIDFGLDLQPTIDLIDKPG---GIMALLDEECWFPKATDKTFVDKLVSAHSMHPKFMKT-DFRGVADFAIVHYAGRVDYSAAKWLMKNMDPLNENIVSLLQGSQDPFVVNIWKDAEIVG----MAQQALT--DTQFGARTRKGMFRTVSHLYKEQLAKLMDTLRNTNPNFVRCIIPNHEKRAGKIDAPLVLDQLRCNGVLEGIRICRQGFPNRIPFQEFRQRYELLTPN------VIPKGFMDGKKACEKMIQALELDSNLYRVGQSKIFFRAGVLAHLEEERDFKISDLIVNFQAFCRGFLARRNYQKRLQQLNAIRIIQRNCAAYLKLRN-WQWWRLYTKVKPLLEVTKQEEKLVQKEDELKQVREKLDTLAKNTQEYERKYQQALVEKTTLAEQLQAEIELCAEAEESRSRLMARKQELEDMMQELETRIEEEEERVLALGGEKKKLELNIQDLEEQLEEEEAARQKLQLEKVQLDAKIKKYEEDLALTDDQNQKLLKEKKLLEERANDLSQTLAEEEEKAKHLAKLKAKHEATISELEERLHKDQQQRQESDRSKRKIETEVADLKEQLNERRVQVDEMQAQLAKREEELTQTLLRIDEESATKATAQKAQRELESQLAEIQEDLEAEKAARAKAEKVRRDLSEELEALKNELLDSLDTTAAQQELRSKREQELATLKKSLEEETVNHEGVLADMRHKHSQELNSINDQLENLRKAKTVLEKAKGTLEAENADLATELRSVNSSRQENDRRRKQAESQIAELQVKLAEIERARSELQEKCTKLQQEAENITNQLEEAELKASAAVKSASNMESQLTEAQQLLEEETRQKLGLSSKLRQIESEKEALQEQLEEDDEAKRNYERKLAEVTTQMQEIKKKAEEDADLAKELEEGKKRLNKDIEALERQVKELIAQNDRLDKSKKKIQSELEDATIELEAQRTKVLELEKKQKNFDKILAEEKAISEQIAQERDTAEREAREKETKVLSVSRELDEAFDKIEDLENKRKTLQNELDDLANTQGTADKNVHELEKAKRALESQLAELKAQNEELEDDLQLTEDAKLRLEVNMQALRSQFERDLLAKEEGAEEKRRGLVKQLRDLETELDEERKQRTAAVASKKKLEGDLKEIETTMEMHNKVKEDALKHAKKLQAQVKDALRDAEEAKAAKEELQALSKEAERKVKALEAEVLQLTEDLASSERARRAAETERDELAEEIANNANKGSLMIDEKRRLEARIATLEEELEEEQSNSEVLLDRSRKAQLQIEQLTTELANEKSNSQKNENGRALLERQNKELKAKLAEIETAQRTKVKATIATLEAKIANLEEQLENEGKERLLQQKANRKMDKKIKELTMNIEDERRHVDQHKEQMDKLNSRIKLLKRNLDETEEELQKEKTQKRKYQRECEDMIESQEAMNREINSLKTKLRRTGGIGL-SSSRLTGTP------SSKRAGGGGGGD----------DSSVQDESLDGEDSAN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P08964-1", "uniprot_id": "MYO1_YEAST", "id": "P08964-1", "name": "Myosin-1", "aln": "-----------------------------------------------MTGGQSCSSNMIVWIPDE-------KEVFVKGELMSTDINKNKFTGQ--EEQIGIVHPLDSTEVSNLVQVRISDVFPVNPSTFDKVENMSELTHLNEPSVLYNLEKRYDCDLIYTYSGLFLVAINPYHNLNLYSEDHINLYHNKHNRLSKSRLDENSHEKLPPHIFAIAEEAYENLLSEGKDQSILVTGESGAGKTENTKKILQYLASITSGSPSNIAPVSGSSIVES-----------------------------------------FEMKILQSNPILESFGNAQTVRNNNSSRFGKFIKIEFNEHGMINGAHIEWYLLEKSRIVHQNSKERNYHIFYQLLSGLDDSELKNLRLKSRNVKDYKILSNSNQDIIPGINDVENFKELLSALNIIGFSKDQIRWIFQVVAIILLIGNIEFVSDR-AEQASFKN--DVSAICSNLGVDEKDFQTAILRPRSKAGKEWVSQSKNSQQAKFILNALSRNLYERLFGYIVDMINKNLDHG-SATLNYIGLLDIAGFEIFENNSFEQLCINYTNEKLQQFFNNHMFVLEQSEYLKENIQWDYIDYGKDLQLTIDLIESKGPPTGVLPLLDEEAVLPKSTDESFYSKLISTWDQNSSKFKRSRLKNG--FILKHYAGDVEYTVEGWLSKNKDPLNDNLLSLLSSSQNDIISKLFQPEGEKSSSAGVEANISN---QEVKKSARTSTFKTTSSRHREQQITLLNQLASTHPHFVRCIIPNNVKKVKTFNRRLILDQLRCNGVLEGIRLAREGYPNRIAFQEFFQRYRILYPENSTTTTFSSKLKASTKQNCEFLLTSLQLDTKVYKIGNTKLFFKAGVLADLEKQKDVKLNNIMIKLTATIRGYTVRKEITYHLQKLKKTRVIGNTFRLYNRLVKEDPWFNLFIRIKPLLTSSNDMTRTKKFNEQINKLKNDLQEMESKKKFLEEKNQKTVNELENTQDLLNQEKENLRKNESLLNRVKTSSETLQKQFDDLVSEKDEISREKLEVAQNLEEAHQKIQGLQETIREREATLEKLHSKNNELIKQISDLNCDISKEQSSQSLIKESKLKLENEIKRLKDVINSKEEEIKSFN---DKLSSSEEDLDIKLVTLEKNCNIAMSRLQSLVTENSDLRSKNENFKKEKAALNNQLKNKESELLKMKEKIDNHKKELATFSKQRDDAVSEHGKITAELKETRIQLTEYKSNYQKIKEEYSNFQRETKEQ-----EQKKRNSLVESLNDSKIKELEARLSQEISLNQYLNKRISGNSVETNISSTRRSTSYSDDPLDKEDIIKKYYDLQLAFTEITRNLENEIEEKKNLISRLRFTETRLASSSFEDQKIKAQMKKLKKLIQDMDPSIPLDS-----------ILNEPLDNCPDKESDINKLMLEVDYLKRQLDIETRAHYDAENAISALHSKFRKIQGESSLSSSDIYKLKFEASEERVKSLEDKLKTMPLRDRTNLPVGDIIKNRDSISKYEEEIRYYKLENYKLQEILNESNGKLSQLTLDLRQSKSKEALLSEQLDRLQKDLESTERQKELLSSTIKQQKQQFENCMDDLQGNELRLREHIHALKQAEEDVKNMASIIEKLKTQNKQKEKLIWEREMERNDSDMQLQETLLELKR------VQDVKKILSDDLAHLKERLSAVEDRSQYTDEINRLKEELNCSLKAETNLKKEFATLKYKLETSTNDSE---AKISDLLKQLDHYTKVVEMLNNEKDAISLAEKELYQKYEALNTECESLKGKIVSLTKIKQELESDLNQKTDALQISNAALSSSTQKNKEITEKIKYLEETLQLQMEQNSRNGELVKTLQASCNGYKDKFDDEKQKNIDLYEENQTLQKLNTDLQLQLKNLHERLSDT--TEKNAWLSKIHELENMVSLETDLKYEEMKKNKSLERAVEELQTKNSQQTDVIELANKNRSEFEEATLKYEAQISDLEKYISQQELEMKKSIRDNSSYRDKVQEMAQEIEFWKSRYES-----------------------TMIGSKNIDSN------------NAQSKIFS------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.::***:::::: **..:* : :***** ************:*::*:** :::. .: :* ::**:*****:****:*::*:*********:*:*: * * **:** ******* ::: **.:**** :::* . ..: *.. . .* :* . : :* :: :.:: ::*:..:: :::: : :* :*.: * :: :**:: : .. :. *:. .*: ::* *: *.*:: * :::..:*..* ::*::: *:*:* ::: :*: **: .::*:**:******* *****************:**: **:***.** :*.*:*.:**:* *** *:**: . *::.*****. :**:** :* .** . . : . * :: * : **** *:*.. ** ** ****:*: :**. *.. :: .::: : . ::.. *:*.. ::*. .*: * .* .:********: *: .:: *:*:** *********:.*:*:**** *:** ***.:* . .* . *: * :: *:**.::*::* :*:**::****.**:::*.*:.:::: : * **: *: : ::*. ::: .. * * : *:.*: ::** : : : .: . . . .: * : :. *.* : : : * .* ::.:: : : . ::.: .: : :.* :*.: :. * *:** :: : :: :*: . *: .:. * .:: : . :** * : : : : * :*. ::: *.*: * :.: . : ::* .: : *:: :: ::.:*: :: :: : . : : .: *:.. : : . :. : :* :* .::::: * .:.: : :: : : :: : : . . ::::.: :* *** *: : . : : . : . :: *:. . ::: *.:*: :* ::. . : : :*: : *: :. * : * :. :: ::*: : .:: : :.: .: : : ::.: :: . :* :: .. : : : :*:. ::: . : . : :. ", "identical_positions": 295, "similar_positions": 463, "identity": "14.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101130-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3MIN7-1", "uniprot_id": "RGL3_HUMAN", "id": "Q3MIN7-1", "name": "Ral guanine nucleotide dissociation stimulator-like 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MERTAG---------------KELALAP--LQDWGEETEDGAVYSVSLRRQRSQRRSPAEGPGGSQAPSPIANTFLHYRTSKVRVLRAARLERLVGELVFGDREQDPSFMPAFLATYRTFVPTACLLGFLLPPMPPPPPP--GVEIKKTAV---------QDLSFNKNLRAVVS-VLGSWLQDHPQDFRDHPAHSDLGSVRTFLGWAAPGSAEAQKAEKLLEDFLEEAEREQ-EEEPPQVWTGPPRVAQTSDPDSSEACAEEEEGLMPQGP-----------------------QLLDFSVDEVAEQLTLIDLELFSKVRLYECLGSVWSQRDRPGAAGASPTVRATVAQFNTVTGCVLGSVLGAPGLAAP-----------QRAQRLEKWIRIAQRCRELRNFSSLRAILSALQSNPIYRLKRSWGAVSREPLSTFRKLSQIFSDENNHLSSREILFQEEATEGSQEEDNTPGSLPSKP--------PPGPVPYLGTFLTDLVMLDTALPDMLEG-DLINFEKRRKEWEILARIQQLQRRCQSYTLSPHPPILAALHAQNQLTEEQSYRLSRVIEPPAASCPSSP----------RIRRRISLTKRLSAK-LAREKSSSPSGSPGD------PSSPTSSVSPGSPPSSPRSRD-APAGS--------PPASPGPQGPSTKLPLSLDLP-SPRPFALPLGSPR---------IPLPAQQSSEARVIRVSIDN-----DHGNLYRSILLTSQDKAPSVVRRALQKHNVPQPWACDYQLFQVLPGDRVLLIPDNANVFYAMSPVAPRDFMLRR----------------------------KEGTRNTLSVSPS-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UYI5-1", "uniprot_id": "RGL3_MOUSE", "id": "Q3UYI5-1", "name": "Ral guanine nucleotide dissociation stimulator-like 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------MERTAG---------------KELALAP--LQDWGEETEDGAVYSVSLRRQRSQR-STPERSGEGQTPIPATDTFLHYRTSKVRALRAARLERLVHELVSGDREQDPGFVPAFLATHRAFVPTARVLGFLLPPPPPPPPPPAGVDSKRTEG---------QDLNFSKNLRAVVS-VLGSWLRNHPQDFRDPPDHQNLGNVRIFLGWAAPGGAEAREAEKLLEDFLKEAKGEQTEEEKRLAWSGPPRIAQTPGSEFAEDCVEEE-GPSSEGP-----------------------ELLDFSVDDVAEQLTLMDVELFLRVRSCECLGSMWSQRDRPGAAGISPTVRATVAQFNTVTGCVLGSVLAAPGLAAS-----------QRAQRIEKWIRIAQRCRELRNFSSLRAILSALQSNPIYRLKRSWGAVSREPLSVFRKLSQIFSDEDNHLSSRAILSQEETTE---DDDCPSGSLPSKL--------PPGPVPYLGTFLTDLVMLDTALPDTLKG-NLINFEKRRKEWEILARIQQLQQRCQRYSLSPRPPILAALRAQRQLSEEQSYRVSRVIEPPAASCPSSP----------RIRRRISLTKRLSAK-LSREKNSSPGGSPGD------PSSPTSSVSPGSPPSSPRNREPPPPGS--------PPASPGPQSPSTKLSLTMDPP-GPWPVTLTPSSSR---------VPLLGQQTSEARVIRVSINN-----NHGNLYRSILLTCQDKAPSVVQRALEKHNVPQPWARDYQLFQVLPGDRELLIPDGANVFYAMSPAAPGDFLLRR----------------------------KEGTGHTLSASPT-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58JT77-1", "uniprot_id": "A0AC58JT77_DANRE", "id": "A0AC58JT77-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------MRSCLLVSGGEKGLRARLGRMRQLLCQTDHVEIQVDEEPGVWLRSFHLLDLQEHTEDP--VQEWGEEVEDGAIYGVTLHREPIQP--PPD-----ATESDAAFGFMQYRTLKVRRLKAATLDRLVTELVNPECP-DPDYMHIFLSTYRAFTCTNALIELLFQ--------------REDMV---------TNLNNSVCVKSSLPRLIRLWLDEFHEDLRDSPDHQALRLLCVHLRHRLCCRRLVNQADALLRKFQTED---------KQICTSAEVSASAVENPATEDNLDGQ--EVQEIG-----------------------DVLDFPAQDIAEQLTILDAELFSKVVPFHCLGCIWSQRDKKENQNLVSTVRATIAQFNVVTNCVITSLLCPPATSPPGSPPCHRSSPTYRAKIIEKWISVAQECHQLRNFSSLRAILSALQSNAVYRLKKTWAVISRESMAVFEHLCDTFPDENCVLINREILVEEGNQAADVETYSAPKSPRLSPTCKH-MSSSSGEVPYLGTYLTVLTMLDTALTDNVEG-GLINFEKRRKEFEILSLIRQLQASCAHYTLQSHPRIISWINSSMSLSDQKSYELSRELEPPVDPCPSSPNSWSHRLIAKKLNLLLSATENFSRKTLADQISVSSSGSSGSDMEDLGRDLSSPNLSPLVYKSPSVSCQDISVDT--------PTSSPTPP-PSCQRSLQADLPESPSSTSSSSSSSSPSLHQRCALHPMYNKQVADSCIVRVSVEFG----NNGNVYKSILITSQDKTAQVVQRALEKHNLEEMNCQDFTLTQVLSNDKELLIPDKANVFYAMCTTANYDFVLRQRYKHLSRATGPSWSPGAVGFPNFSSRYPQNGSDLRLPISSEVVINLACNRTHQ-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PCE9-1", "uniprot_id": "M9PCE9_DROME", "id": "M9PCE9-1", "name": "", "aln": "MNFTSRANCKCPHSQKHQQKPALIKSHTCAYQLQDLTGYNRALMPPLDNTDFSNAWRQVNNNTTSQSCAYHQQRQQQQQQQDAKDSKRHYHHHTCPRQRKKSMTPVEPTHLCQKHQEAKQRRSRSASAKPRRNSSYHSYDDLDVSSAVLNAERKVVASLKYLCACTGATLRNLSKKTKDLHAKNYTYTKPTWRLWGEEHEKNAIFTVYLKKVRYHRPTPTAS-----NDSDDEISHLEWETVRVRFVKAATLARLVEALATDDGELESTFINVFLSTYRTFSTPKQVLSLLTQRYDALHEKHLEELEQAQQNGQVMDPAYDPHASIHEQHKKTLVSALHVWLDGFPEDWHEDNLQQILAFATKRLKRSDLHIKVLNRLERLIKQSLYGNGGGSGGSENNGHSWLSAARSQQMQQFMIPTHYGSSYDLTDQFNGMYLSPMGHGPIYRGPTHFLQAFRFPHVPVRHFAEQLTRMDTELFKRLIPHQCLGHTWARRDSGGSE----TVVATINQFNAVLFRVVSSILIDRLKPQE------------RALNISRWIDIAQELRMLKNFSSLKAIISALNSNSIYRLSKIWEVLPKERMEVFTELANICSEDNNAWTLREVLKREGTAKNPDPGSDHSDRHLQKLILNLGTQTSHGTIPYLGTFLTDLTMIHTANPDYLTENKLINFDKKRKEFEVLAQIKLLQGAANTYNLQADALFDHWFNSMPVFDEREAFELSCRLEPPPPAPRKSVVSTN----TSLTNTTASSTASIMGHRKTDSIHSNSSSGAGSQFYCELNSSTSSRHNSLDRDVHHQHASLMSASSSVSNLSLDSSNSGGRQSGKLTHSQSMGNGLKSHGNGTTNGGSPHINAQLVQPSSGTPHSAPDFYIIRVTYETDNIELDGIVLYKSIMLGNNERTPQVIRNAMLKLGLED-DPDRFTLAQVLP-DKELVMPKNANVYYAVNTNYNLNFILRPR--------------------------KEEGVAGSXSTAVPLSQLWCLGYEGEE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. :: : : **** *..*:: * *:: : .. .:.:.* :** ::** * *** *. : :. :: **:*:*:* . :: :* : . . : : : ** . :* :: :. * * .. : *:.. . :. . : . .... ..***** :* *** :: .*** *::** ** **: ***.* *: *:* . ** :.:** :**. : *:*****:**:***:**.:***.: * .:.:* : .* .*.: .::: * :* .* . . . * :*****:** *.*:.** .* : ****:*:***:*:*: *: ** . *.*.. . : :.: : :.:::.:* :*** . .* . * * : : : . ......*. . .:. .. . . .: .. * . . . . . ... . :. .: ::**: : : :*:**:: ::::..*::.*: * .: : : * ***. *: *::*. ***:**: . :*:** ::* . : ", "identical_positions": 146, "similar_positions": 217, "identity": "14.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101130-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C2K5-1", "uniprot_id": "RASL3_MOUSE", "id": "Q8C2K5-1", "name": "RAS protein activator like-3", "aln": "--MKPECGQTMFRTFWSRSRDSSAMDPPLQSEEDSQTQPSLPSPLTSYRWHTGGSGEKAAG----------GFRWGRFAGWGRALSHQEPMVNSQP---------------APRSLFRRVLSAPPKESRSNRLRFSKTLWGRHKNVAPL------------------EPKPNPKAPEPELELVADPDLPVAQIPEPPTPDMPVWNIDGFTLLEGKLVMLG-EEEGPRQI-RVGSASSENSMQAALGNLKDAVRTPGKTEPEAAGSNQVHNVRKLLKR-LKEKKRAKSELGAYTPRDGPPSALGSRESLAT----LSELDLGAERDVRVWPLHPSLLGEPYCFQVTWAGGSLCFSCRSSAERDRWIEDLRRQFQPSQDNVERQEMWLTVWVHEAKGLPRATV--PGVRAELWLDGALLARTAPRAG-------------------------PGQLFWAERFHFEALPPARRLSLRLR-SAGPAGATVGR---VVLELDEVSIPRAPAAG---LERWFPVLGAPAG------------AVLRARIRVRCLRVLPSERYKELAEFLTFHYARLCGALEPALSAQAKEELAAAMVRVLRATGRAQALVTDLGTAELARCGGREALLFRENTLATKAIDEYMKLVAQEYLQDTLGQVVRCLCASTEDCEVDPSKCPTPELPKHQARLRDSCEEVFENIIHSYNCFPAELGSVFSSWREACKARGSEALGPRLVCASLFLRLLCPAILAPSLFGLAPEHPAPGPARTLTLIAKVIQNLANCAPFGEKEAYMAFMNSFLEDHGPAMQHFLDQVATVDADTTPSGYQGSGDLALQLAVLHVQLCTIFAELDQKTQDSLEPLPTILRAIEEGRPVPVSVPMRLPRISTQVQSSFFSGEKPGFLAPRDLPKHTPLISKSQSLRSFQGAG--SWASRRPDEERPQRRPRPVLRTQSVPARRPTHRRPSAGSKPRPKGSLRMGPAPCGRAWTRASASLPRKPSVPWQRQMDQPGDRYQTTGTHRPVGKLAEIQCEVAIFREAQKALSLLVESLSTQVQALKEQQEHFRCQLQDLYSRLGAGISKLDSKGGLPSNGSHRLKSLEQRLTEMECSQDQLRDSLQSLQLLSKTPG-SRSQPLPLKAPCVNGADLSMGT-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86YV0-1", "uniprot_id": "RASL3_HUMAN", "id": "Q86YV0-1", "name": "RAS protein activator like-3", "aln": "------------------------MDPPSPSR-TSQTQPTATSPLTSYRWHTGGGGEKAAG----------GFRWGRFAGWGRALSHQEPMVSTQP---------------APRSIFRRVLSAPPKESRTSRLRLSKALWGRHKNPPP-------------------EPDPEPEQEAPELEPEPELEPPTPQIPEAPTPNVPVWDIGGFTLLDGKLVLLGGEEEGPRRP-RVGSASSEGSIHVAMGNFRDPDRMPGKTEPETAGPNQVHNVRGLLKR-LKEKKKARLE-----PRDGPPSALGSRESLAT----LSELDLGAERDVRIWPLHPSLLGEPHCFQVTWTGGSRCFSCRSAAERDRWIEDLRRQFQPTQDNVEREETWLSVWVHEAKGLPRAAAGAPGVRAELWLDGALLARTAPRAG-------------------------PGQLFWAERFHFEALPPARRLSLRLR-GLGPGSAVLGR---VALALEELDAPRAPAAG---LERWFPLLGAPAG------------AALRARIRARRLRVLPSERYKELAEFLTFHYARLCGALEPALPAQAKEELAAAMVRVLRATGRAQALVTDLGTAELARCGGREALLFRENTLATKAIDEYMKLVAQDYLQETLGQVVRRLCASTEDCEVDPSKCPASELPEHQARLRNSCEEVFETIIHSYDWFPAELGIVFSSWREACKERGSEVLGPRLVCASLFLRLLCPAILAPSLFGLAPDHPAPGPARTLTLIAKVIQNLANRAPFGEKEAYMGFMNSFLEEHGPAMQCFLDQVAMVDVDAAPSGYQGSGDLALQLAVLHAQLCTIFAELDQTTRDTLEPLPTILRAIEEGQPVLVSVPMRLPLPPAQVHSSLSAGEKPGFLAPRDLPKHTPLISKSQSLRSVRRSE--SWARPRPDEERPLRRPRPVQRTQSVPVRRPARRRQSAGPWPRPKGSLSMGPAPRARPWTRDSASLPRKPSVPWQRQMDQPQDRNQALGTHRPVNKLAELQCEVAALREEQKVLSRLVESLSTQIRALTEQQEQLRGQLQDLDSRLRAGSSEFDSEHNLTSNEGHSLKNLEHRLNEMERTQAQLRDAVQSLQLSPRTRG-SWSQPQPLKAPCLNGDTT-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FDZ7-1", "uniprot_id": "E7FDZ7_DANRE", "id": "E7FDZ7-1", "name": "", "aln": "MGTNKESNAEQAGAASQIEEDMELVPEQNSPVDQDPRQTEDGKLLNTYKWHTGAKAETVAQGAIERLEKGASNKWNKMQSWRKALSEDPGEKSSTANRGGESPSKPDKPTTSRKNPFRRALSEPPGSLLASSAPASSSAQATGSTVQDTTQRGKIRKYLQTVSQRFKKPRLQSTVTEHEKCEPDYVLQDPVRLSWAPPQEVPVWDISNCFLQDGQILIPREEEPMMTVRNRASSCLFSVSLQNISGSHAELNPDPVVPSSGTKLKGQDGGVKGLIKRRLQGDDKRKSSTQLNTAGLSVAARYGSKESLSIPVSAAKSLNLSADQTTVIRPVHSSILGEKYCFQVINSENNHCFGCTSAAERDRWIEDLRRTAHPNKDNCERTENSLCLWINEAKDLPPKKR----YYCEVHLDGTLFARTSSRAVGKSVQRSSQAVDGGSGAFGSGGTSGGCQLFWGEFFELDNLPPVTQITLHLFKGEDPKKKRHSRDDATLHPLGSVALPLADIKGRAYQEKWYRIVAYKPPGTSTAKDSVELQASIRVKAKFKNLKILPIERYKEFAEYVTVNYVDMCSSLEPLLNVREKEELAGALVHVLQSIGKAKEFLIDLGSAEVQRLGENEALIFRENTLATKAIDEYMKLVGQKYLIDTLGDFIARLYNGGENCEVDPLKCSPSDLPINQRHLKETCEDVVKRITDMQESFPAELNDIFSSWVSDCEDRGQQDIGQRLISASLFLRFLCPAILSPSLFGLTQPYPETNTLRTLTLTAKVIQNLANFTLFGEKEEYMFFMNDFLTQHWEPMRDFLQKVSNPESEITMSRFDGYVDLPLRLAVLHNLLVDIISVMKQDQIDNLHPLPRILNQIT---EFLGHDAQQIPVSSNQAMP------KPIYVPPRDLPKYSPLQTSMQQLPIDSKPNQCTKERQRRQVQRAFSVPNRPSRQQRQPMKRQASNEELPTQCPDDNQDHRLEISPPSNPEKSKAAAAAK---VHWIKQPDGSETCQVRRQDREETNTLDKHAQELSELRMGVEQVTERELEMAKRLEDFIVLTQDQNAQLQAEVQDLRN---LLAIREEQLASATFRLGVIEEEREEDERKLNVAVAAVERMNVLEEQFAGLLKDVHHLYAANSDGLRQTYINT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . *. . *.:*:****. .*..* . :*.:: .* :***.: .: . : :. ***.** ** . :. *.: . .. :* :. * ::. .*. ::***:*.. * :*:::: ** *..*. . *:: *. : * ... : .* .*: *:** *: ..: : . . . .: **:***: ..*:*.*:: . : *:*.*:*** :**** : .. **.* *:************ :*.:** ** * * :*::***.** .*: ***:*:***:.** ****.* *.:: ***. :::*:* . .* .* . * .: * * * *:*: ::. . * :*.: : : *::** *****:**::*.:*. :*.:*** * .: *****.*:*:**:: *:*: :: ***:**: * * .***:******************.*.** :***:.: * . *:***** **...:** :* :*:::**:*.: * . : *****. :**** . *: **.: :* **:.******:******:******: :* ... ***** ********* : ***** ** ***.** :* .*: **::*: : : : * ::* **.*:***** * *:: :.* *.*.*** **. * . . ::* . *. . ** ::.******::** :. *.* . : * : :*. *. * * * :* : .. . * : . : :* ... . :*: .: * * :* * . :. ...* : *:: :* : :: .::.::. : :. . *** . * : . :. . * :*.. * * . ::: ::: . . .: * *. :* ", "identical_positions": 329, "similar_positions": 309, "identity": "28.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101130-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7Z5J1-1", "uniprot_id": "DHI1L_HUMAN", "id": "Q7Z5J1-1", "name": "Hydroxysteroid 11-beta-dehydrogenase 1-like protein", "aln": "MKVLL-LTGLGALFFAYYWDDNFDPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVFYIAADMASPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAITMCVLGLRDRASAAEAVRSSTSRPRQPEHRGVPLQSQTAMFLPPTVPGARTLTETPLRGWPQPKMKSSRQKSKTEKNDGHLEPVTAWEVQVPRVRRLCRGLARPHLFGHD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q5R7-1", "uniprot_id": "A0A2R8Q5R7_DANRE", "id": "A0A2R8Q5R7-1", "name": "", "aln": "MKVLFGVFLLIAVLTSLMWRDTFDPESIRGTRVLITGASSGIGEQMAYHYAKFGAEIVITARRLEALKKVTQKCEKLGAKKIMYVTGDMSDPADPERVLKYTIEKLGGLDFLVLNHVGNTNVGLWNRDADHVRSLMQVNFVSYVQMAGAALPVLETSGGSIIVVSSLAGKIASPFVTPYSSTKFAMNGFFGALQKELAIQKSNVSVSIQILGLIDTESAMRKIR-----------------------------GYTTMTAYPASEAALSIIKAGATRQKVAFYPWFHYLTCLINDIFPFLTDLLSGLRWD------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****: : * *:: : * *.*** *::*:***:***.:*:**::*****::*:.:*:**: *:**. :*.**** *::*::.**:.* ** *::::::******:*****:*.: .* *..: .* ***********::. *** * * **::***** *::.:.* ****::***::****:*::** :*. **:::: :*** * ** . :* * *:* * . . :*:. :.*. . . : .* : * ** ", "identical_positions": 121, "similar_positions": 88, "identity": "38.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101202-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BUD0-1", "uniprot_id": "GPR4_MOUSE", "id": "Q8BUD0-1", "name": "G protein-coupled receptor 4", "aln": "MDNSTGT------GEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVRQHNELGVYLMNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYSNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMERWVAWMNLYRVFVGFLFPWALMLLCYRGILRAVQSSVSTERQEKVKIKRLALSLIAIVLVCFAPYHALLLSRSAVYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKALHNLLRFLASNK-PQEMANASLTLETPLTSKR-STTGKSSGAVWAVPPTAQGDQVPLKVLLPPAQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P46093-1", "uniprot_id": "GPR4_HUMAN", "id": "P46093-1", "name": "G protein-coupled receptor 4", "aln": "MGNHT--------WEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHVLLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKALHNLLRFLASDK-PQEMANASLTLETPLTSKR-NSTAKAMTGSWAATPPSQGDQVQLK-MLPPAQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FEL0-1", "uniprot_id": "GPR4_DANRE", "id": "E7FEL0-1", "name": "G protein-coupled receptor 4", "aln": "MASLRGSETMCNITTSCNVDSNIDQFFQPTLYIIVIVLGFPTNCMALWAAYMQVKQKNELGIYLMNLSIADLLYITTLPLWIDYFVHHDNWIHGQVSCKLFGFIFYTNIYVSIAFLCCISVDRYLAVAHPLKFAKVRRVKTALLVSAIVWLTEIVANSAPLFHDELFQDRFNHTFCFEKYPMEPWVAGMNLYRTFLGFLAPWGIMLAAYRGILRAVRGNVSTERQEKAKIKRLALSLILIVLLCFAPYHVLLLWRSVLFLINPCDCGGEENLFGAYHVTLALTSLNCVADPILYCFVNEGARHDVGRALATLLGLFQRGKSPETLMGASITVETPLAVKKPDFYSEVKTNAYKNDIEVLKDECLQMTILSVKK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .*:***.:*::* *:***:** :*:****:****** **:*:****:************* *****:***:******** **********:***:********************:**::******: **::** **: ************:**:********:*** *** *****.*:*** **.:** .********:..********.********** ***:******.*** **.::* .* *** **.:*.*** :**:*************:****** **.:** .** :: .* *: : .**:*:****: *: . .: : *: :*. :", "identical_positions": 238, "similar_positions": 71, "identity": "63.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101202-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADE7-1", "uniprot_id": "D4ADE7_RAT", "id": "D4ADE7-1", "name": "DNA-directed RNA polymerase I subunit RPA34", "aln": "-------MEGTSACGATR---FSCPPHFTAMSPDSDPPRFSLEALTG-PDTEVWLIRAPADFAPQCLNGRRVPLSGSKTVKGKLDGKKHRYRVVTSGPQAGEATLLMSSMEAGGRLACAPAPNGSLRIMEGPQEYLISRVPLQPIPTSLPPQIPAGLRPRFSAFGGSPPVTGPGSASVLRSPTSGKRKKKRKDAEAS-DTQEAVNRHEAMKVETAWGDLGMDVKKK-RKRHHVDEEAEAKG---MEPLAE-LAELPVPSATGSKKRKKSKGAETLQAEEDPGHMEPVAQTEPPEGPFLSPTKKRKRQKQAEGAEEVDGTMADSQPQVTVEPHEETILLSPTKKRKKEKRQNLVMEA----------EMG---LPGVLMETELLEPG-LQAEVAPVSPKKTKKKKKGKCVDEALALAAEVTEAALPADFEPQGAPVPSKKK----ERGQKATEPGSEVTDPRQSE-EPEPRAGQGSPKKKKKKDQESRVQNTIPH--------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q76KJ5-1", "uniprot_id": "RPA34_MOUSE", "id": "Q76KJ5-1", "name": "DNA-directed RNA polymerase I subunit RPA34", "aln": "-------MAGTQACSATR---FSCPPHFTEMSPDSEPSRFSLEALTG-PDTELWLIQAPADFAPQCLNGRRVPLSGSKTVKGKLDGKKHRYRVFTSSPQAREATLLASSSEAGGRLTCAPAPSGSLRIMEGPQEYLLSRVPLQLIPTSLPPQIPAGLRPRFSAFGGSPPVTGPGSASALRSPTSGKRKSTRKGTDASSDTQEAVNRHGAMEVKTALGNLGVSVKK--RKRYFMQEEMEAKT---MEP----VAELPVPSATSSKKRKKSKGTETSQVE----HTEPVAQTEPPEGTFLFPTKKRKRQKEADGTEEVDGIVADSQPQVIVEAQEETILLSPTKKRRKEKRQNLGMEA----------EMG---PPGVLMVTEHSEHG-LQAEVALVSPKKTKKKK-GKRVGE--------TEAALPDDFEPQGALAPSKKK----ERGARL----------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15446-1", "uniprot_id": "RPA34_HUMAN", "id": "O15446-1", "name": "DNA-directed RNA polymerase I subunit RPA34", "aln": "-------MEEPQAGDAAR---FSCPPNFTAKPPASESPRFSLEALTG-PDTELWLIQAPADFAPECFNGRHVPLSGSQIVKGKLAGKRHRYRVLSSCPQAGEATLLAPSTEAGGGLTCASAPQGTLRILEGPQQ-SLSGSPLQPIPASPPPQIPPGLRPRFCAFGGNPPVTGPRSALAPNLLTSGKKKKEMQVTEAP-VTQEAVNGHGALEVDMALGSPEMDVRKKKKKKNQQLKEPEAAGPVGTEPTVETLEPLGVLFPSTTKKRKKPKGKETFEPEDKTVKQEQIN-TEPLEDTVLSPTKKRKRQKGTEGMEPEEGVTVESQPQVKVEPLEEAIPLPPTKKRKKEKGQMAMMEPGTEAMEPVEPEMKPLESPGGTMAPQQPEGAKPQAQAALAAPKKKTKKE--KQQDATVEPETEVVGPELPDDLEPQAAPTSTKKKKKKKERGHTVTEPIQPLEPELPGEGQPEARATPGSTKKRKKQSQESRMPETVPQEEMPGPPLNSESGEEAPTGRDKKRKQQQQQPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WGE9-1", "uniprot_id": "X1WGE9_DANRE", "id": "X1WGE9-1", "name": "", "aln": "MSDSEEETREPTSGGRKRDSKYQCPAEFISFPYDS-----SVNALLGEEKQQLWFIKAPARFDPKCFNNLQLPLSGLGMVQSKGNSP-QIYSVVSGGTTPSDLNLLISKGENQKLSLCSTGFSGVLKISESYGDCGETQGPIP-VPAAPAPRIPDGLKQRFHPFGSSTGARMQKEATFASPTPLQKTRQDVGDGDEP------------------------------------------------------------------KKKKKKK-------------------------------KDKSQGDSGDVFIKQEETQIECNQLEISELMEEEPMEERRRKKKKVKKEKERENP----------DMVD---ASLFLKTEQLDPSYDDTEVTPGKTKKKKKKS--------------------------------SRNE--------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . * :.**..* . * *::** * . ::*:*:*** * *:*:*. ::**** *:.* . : * *.:. . . : .** .. * *:.. .* *:* *. : : *: :*:: .*:** **: ** .**... . .* . * :. : . **:** * *.:.: . : : :.: * ** :*::* * : :. :* .. : .: : . :::.: .**..**. :::: ", "identical_positions": 64, "similar_positions": 97, "identity": "12.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101202-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9PVB3-1", "uniprot_id": "CC175_MOUSE", "id": "E9PVB3-1", "name": "Coiled-coil domain-containing protein 175", "aln": "MAIRSWTPEGFVNKKLVRPASVSTNLSLELCTFPTTLGSSVAANALEQLFVVEKSLQGDYFTCSEEVKTFLKDITVAVKKLEEMRKNTVELLEIESMELSRLYFLLETVPNSIHRELEECIADARKLNIIEISQIKRKIETMNNEVKFLTNKISELKSMNEVLGAKQAELAKRHEQYVLLLNQTLEEKAAATIYINDTYTRMNFEREEIELQKQCMQETTQLIEKQKQDYLEKKEYLAIRIKETKQSCDDKRKETYYKKKELTRLQNKIIKMKQTVTSGSVMISDQSIEINILHEAITIWKKKVEDMRRLCESLEEKLSFFVTQKQNLDTTSTEKKNAFVNKIQKLGEKIYKLNTENEDLREKLSTLLKQYKATLKEEEAVSLKKQMLSEEHQKQMMVITQKEAFLSQREHDIKFMENGFGVLNDLNRASREAYGRQIEVMAKNRQREIQRCVINQWRIFCTRKRHAHWLQKIKLSLKKIIIQIEIVEQKRFQLLEETKHRKKEINHFVHLIETLKEQLAQDKKDYVKKEERLIEELGTYETLILNEIQINKVKEEELGETLPQLQVAEEDFREKNRMLRSLHSDVSAKKQDEKTMSNTIFRYRKDIIRCTDGTENMKREIKHLRDLESEKTHKHFEILKNLENEIYVNDQKMALLILENQKLREYLAYLKKEINEYASKQVVTVQHSGDLSWQLIVQHSHYSDLLSGFQIIIKELVGTGEDTMQEIKSLVAKLQYRDEKIESISTWLVGGFERLRRLMEEDSPASLSKEDLQKLGKKQKNQEILRFSPSSHARRLTLSRICKMLKKQSRSRKKKHRPRTII", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C221-1", "uniprot_id": "CC175_HUMAN", "id": "P0C221-1", "name": "Coiled-coil domain-containing protein 175", "aln": "MALSPWTPGLGAGEKLVQAAAVSTGPSLELCTLPSTLGSSVAVEALEQLFVVEQSLQSDYFKCNEEAKIFLKDIAVAVKKLEEMRKATIDLLEIESMELNKLYYLLETLPNSIKRELEECVRDARRLNLFEINTIKMRITRTENEIELLKKKITDLTKYNEALGEKQEELARKHARFVLSLNQTMEKKATTTVYINETYTKINLKREDIALQKKCIQEAEELMEKERAEYLIRKQELTAQINEFENTREVKRMETYQKKKELDKLQTKMSKIKETVTVSAAVLSDHNLEIARLHESIRYWEQEVSELKKDLAILEAKLCFFTDNKEKLDDISNDEKNEFLNKIKQLVETLHAARMEYKDLREKMKTLARQYKIVLSEEEKAFLQKQKIHDENQKQLTFISQKEYFLSQKRVDIKNMEEGLITLQELQQATKTVYQQQIKILSANLERESQRCVITQWKMACLRKKHARWTAKIKAEIQAITEKIQNAEVRRIELLNETSFRQQEISGFVAQIEKLTTELKEEEKAFVNKEKMLMKELSKYEEIFVKETQINKEKEEELVEYLPQLQVAEQEYKEKRRKLEELSNIITAQRQEEDLLNNHIFLFTRDFSRYISNMEDVKQELQQLRDQESKKNKDHFETLKNLENGFYINDQKADLLLLENKKLKEYILYLKNNIEKYREGQEALMHTSSDLSRQLIAQEAQYKDLWAEFQTTVKILVDNGEETLQDINNLTDKLRERDEKMQHVSTWLRGSLEGLRLLVEQESPMDLLK-------KKKHIRTRVHFPVVKCTEKNTLTK----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WGC2-1", "uniprot_id": "X1WGC2_DANRE", "id": "X1WGC2-1", "name": "", "aln": "---------------------------MATCLVPDFP---AVRIVLEHLSELDKRLREEGVSFSQEASHHLTETAEAIKELESARKAARERLEVETIETSKLRHRKVNLQDDIKREIAVCVTAARESNATALNRLRSELKAAVDDIQSMEDKQQLIEQENAALLQGRENITRNYEDAVDQLNQMLSKKVDTQMLLKEKQNEIQSLKDKIAQVEMAQQILKENRIQRNKIFTESKHSVQKELEQIVLKIKEQRKINAETRRETDSITSELQDKEDTVTQCENHISQLEKNIAKLTASKVHCQERLHKAIGKTEELECQKEFHERELLELAEAFEQKVQAIQEQIEKIENELGEEQKVKSALSEQCAKLSDIFSAQSREEDDMIAEQNSLSKRLEESKQIQDEDIISIAKLKYAIKNIKRETGQLHDANIISADVFRKSTLELEGQLAKHNISRPEFEAEREKIRQSLKTLKEEHEQHVKEMNTAIEQTQKRYEELLKEEKK-LQDHTLLNSVIEGLTNELTSTEEDGKQMETNYQAELQQLTREAESITQTQMEKEQELKVQESSLEMAESQFDTERLKHQTLKRQISELENQKNHLELSVQKITRQTAALIQPKDDLKRELMTLREKHMEMLTANAAEINAVETNIYENGVMLERVMMENSRLHVCIELMKEEIMAAKKDKEKYIQEAEWMNEEVQSIFKSLIDTWTTDVLFTEESADQDQKIVEDINSLLERIQERKHHIGNINNKLEKELVGIRSMLEKTN----------------YKSKDIELKHLHHSTEI--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .* .. .**:* ::: *: : .. .:*.. .*.: : *:*:**. ** : : **:*::* .:* . .: :.*:**: *: **. * :. :: .: :::: : .* : . * .* : ::::.: * *** :.:*. : : :::. ..:: ::.* : . * : :.. : *. : .::: . . :* . .::* : .:: . ::*** :*: . :* * : ::.: . ** : *. : :* :: : : ::*::: : : . . * *: .* :. **: ::: : .. ::. . :. ::: . ** ::. *:: : : .: :. : : :. : . *: : : :: : *: .: : :**:* . :: . : ** *. :* . :: : * ** . * : **:** ..*::**.:: :. . * :: .:::. :. : :: . :::*:*: **: . : : :: :*. :* *. :::**.:*: : :*::* . : :: : :. :: * : : .. .:. :::*:.* ::: *..:: :.. * : :* ::*: . :.: : . ", "identical_positions": 98, "similar_positions": 287, "identity": "11.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101203-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NFA2-1", "uniprot_id": "NOXO1_HUMAN", "id": "Q8NFA2-1", "name": "NADPH oxidase organizer 1", "aln": "MAGPRYPVSVQGAALVQIKRLQTFAFSVRWSDGSDTFVRRSWDEFRQLKKTLKETFPVEAGLLRRSDRVLPKLLGQASLDAPLLGRVGRTSRGLARLQLLETYSRRLLATAERVARSPTITGFFAPQPLDLEPALPPGSRVILPT---------PEEQPLSRAAGRLSIHSLEAQSLRCLQPFCTQDTRDRPFQAQAQESLDVLLRHPSGWWLVENEDRQTAWFPAPYLEEAAPGQGREGG--PSLGSSGPQFCASRAYESSRADELSVPAGARVRVLETSDRGWWLCRYGDRAGLLPAVLLRP---------------------------------------------------------------------------------------------EGLGALLSGTGFRGGDDPAGEARGFPEPSQAT------APPPTVPTRPSPGAIQSRCCTVTRRALERRPRRQGRPRGCVDSVPHPTTEQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VCM2-1", "uniprot_id": "NOXO1_MOUSE", "id": "Q8VCM2-1", "name": "NADPH oxidase organizer 1", "aln": "MASPRHPVSAHAVALVQMDRLQTFAFSVCWSDNSDTFVRRSWDEFRQLQKTLKKTFPVEAGLLRRSEQVLPKLP-----DAPLLTRRGHTGRGLVRLRLLDTYVQALLATSEHILRSSALHGFFVPKPLDLEPMLPPGSLVILPT---------PEE-PLSQPRGSLDIHSLEAQSIPCVQPFHTLDIRDRPFHTKAQEILDILLRHPSGWWLVENKDQQVAWFPAPYLEEVATCQGQESG--LALQGSGRQFCTTQAYEGSRSDELSVPSGARVHVLETSDRGWWLCRYNGRTGLLPAMSLQP---------------------------------------------------------------------------------------------EGLGSLLGRPGFP---DSAGADK----VAEDR------TIPPVVPTRPCMSAIQSRCCSITRRALGQ---EQG------TRVPR-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F6NRK2-1", "uniprot_id": "F6NRK2_DANRE", "id": "F6NRK2-1", "name": "", "aln": "MSDPRFPVDVHLIGVMKKEKDKKYMTSVLWSDQSELIVYRSLRDFRTLHRQLKKKFPVEK-PYRKEDRVLPRFGAQVMKSTFQLKGLDKS---VSRLRNLEKYCSSLLQCDTTVSNSREVIQFFLPTEQELLPEYTQNSVMILQSDNIPTAHGGPDLQKKSLSNGNVTQP-FVSKAYQCVAPYETKDTKNKPFKVAIGERLDVLIKDRAGWWLVENEDKHLAWFPAPFLELCDGEEEEDEDEYNSVTCEMSLYCATRCYTSKKEDELSLSIGAVVELLQRSDNGWWLVRYNNTAGYVPSMYLKLYSSPSFGLQTLQRKLHSSTINLSTSNSPKPEPQRNRINRFLKSSSLEILSEPQSHFTDQVQRQESGSFSDDGTDFSFSSSDTTSMSPSMSSSEEDEGPLIRQDKEADSSDSALSSGQSSPVNSDTGHPMKGVGAPKVPPRPQTREILQRCTTYTRKAALATSVRLAPERQVMVDGGRA----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.**.**..: .::: .: :.: ** *** *: :* ** :** *:: **:.**** *:.::***:: .: * .:: : **: *:.* ** : .* : ** * :* * . .* :** : *: * . * : : ::: *: *: * * :::**:. * **:*::. :*******:*:: ******:** : .: . :: . :*:::.* ..: ****:. ** *.:*: **.**** **.. :* :*:: *: *. *.*: *.* . . .* **.** * .** : **:* . . : ", "identical_positions": 109, "similar_positions": 110, "identity": "22.43%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101203-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LF30-1", "uniprot_id": "A0ABK0LF30_RAT", "id": "A0ABK0LF30-1", "name": "", "aln": "MKTNPAGAPLETCQTAGQGEKGYPVCQACGGASSLGSASESGSGLRPGPGVALDSGLGPGAIPGPGPGPGLGPSAVPGSGPQPSSVSVTGLRPGTTSGPNASLGPGLGTGSLPGPGARSGLRPGCDSVPAPAPQPGSGPVPQSGSGPVPQSGSGPVPQSGAGSVSQPGAGSVPQPVSELVTSPGAAPLPGLGLGPGTRRGSGTGSNPGESVRATVPALQQKTEAKHTQAPRQKVLVTGGGGYLGFSLGSSLAKKGASVILLDLRRPQWPLPSGTEFIQADVRDEEALYQAFQGVDCVFHVASYGMSGAEKLQKREIESINVGGTKLVINVCVRRRVPRLVYTSTVNVTFGGKPIEQGNEDSIPYFPLDKHMDHYSRTKAIADQLILMANGTPLLGGGTLRTCVLRPPGIYGPEEQKHLPRVASHIKKRLFMFRFGDRRTHMNWVHVQNLVQAHMRAAEGLTLAKGYVASGQAYYIHDGESVNLFEWMAPLFEKLGYSQPWIQVPTSCVYLTAAVMEFLHLALRPICTISPLLTRSEVL-SMTVTHTFQIAKARAQLGYAPDKFSFADAVERYVQATTPQPCCCTVLTLLRLLLLLLLLLGLLGLALYFLGLQPLQAVVERL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A140LI11-1", "uniprot_id": "A0A140LI11_MOUSE", "id": "A0A140LI11-1", "name": "", "aln": "MKTNPAGSPLETCQTAGQVQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QQKTQAKHTQAPRQKVLVTGGGGYLGFSLGSSLAKRGTSVILLDLRRPQWPLPSGTEFVQADVRDEEALYQAFQGVDCVFHVASYGMSGAEKLQKQEIESINVGGTKLVINVCVRRRVPRLVYTSTVNVTFGGKPIEQGNEESIPYFPLDKHMDHYSRTKAIADQLTLMANGTPLLGGGTLRTCVLRPPGIYGPEEQRHLPRVASHIKKRLFMFRFGDRKTRMNWVHVQNLVQAHMLAAEGLTMAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQPWIQVPTSCVYLTAAVMEYLHLALRPICTIPPLLTRSEVRGVVAVTHTFQIAKARTQLGYAPDKFSFADAVERYVQATTPQPRCCIVLTLLRLLLMLLLLFALLGLALYFLGLQPLQAVVERL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NKP2-1", "uniprot_id": "D42E2_HUMAN", "id": "A6NKP2-1", "name": "Putative short-chain dehydrogenase/reductase family 42E member 2", "aln": "MKSNPPRSSLEACKAAGQAP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QQKTQAKPTKAARQKVLVTGGGGYLGFSLGSHLAKSGTSVILLDRRRPQWELSPETKFIQADVRDEEALYRAFEGVDCVFHVASYGMSGAEKLQKEQIESINVGGTKLVIDVCVRRRVPRLIYTSTVNVAFGGKPIEQGDEDSVPYFPLDEHVDHYSRTKAIADQLTLMANGMPLPGGGTLRTCVLRPPGIYGPEEQRHLPRVAGHIKKRLFMFRFGDHKARMNWVHVHNLVQAHVLAAEALTTAKGYVASGQAYYINDGESVNLFEWMAPLFEKLGYSQPWIQVPTSWVYLTAAVMERLHLALRPICSLPPLLTRSEVR-SVAVTHTFQIAKARAQLGYAPDKFRFADAVELYVQSTTRRPRGSTARTLLRLLLRLLLFLGLLALALHFLGLQPLHAAVERL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RIK4-1", "uniprot_id": "A0A8M1RIK4_DANRE", "id": "A0A8M1RIK4-1", "name": "", "aln": "MKENRSSCQMEQLPCACLLDCHRQTHSRSAAATIPLRHRANG------------------------------------------------------------------------------------------------------------------------------------------------------------------AVGALCSSPNCVVSDRLEDSGKGRFGTGRVLVTGGAGYFGYRLGRALARQGAAVVLLDLHQPPWDIPDGAVFQQIDIRDYDTLYKISAGVDVIFHTASYGMSGPEQLRKKQIESVNVGGTNNVINVCAERGISRLIYTSTVNVAFAGRPIEDGDEDSVPCVPLDMHIDHYSRTKAIAERMVLAANRRSTKGGGLLHTCVLRPSGIYGPEERRHLHRVMVNVERRFFSFCFGDPNAKMNWVHVDNLVTAHVLAAQALTAEKAFVASGQAYFINDGESVNVFEWLTPLFERLGYGRPLIHLPVSLVYSAAILMERLHVALRPIVEIPLLLTRNEVR-NIAVSHTFKIEKAQRDLGFSPQRFSLKDSVDQYLQS---RPVRSASSFSAQHLMLLLLICGFFALFMHCLA-----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * . . :* * :: :: : :******.**:*: ** **: *::*:*** ::* * :. : * * *:** ::**: *** :**.*******.*:*:*.:***:*****: **:**..* :.**:*******:*.*:***:*:*:*:* .*** *:**********::: * ** . *** *:******.*******::** ** ::::*:* * *** .::******.*** **: **:.** *.:*******:*:******:***::****:***.:* *::*.* ** :* :** **:***** :. ****.** ::*:***:* **: :**::*::* : *:*: *:*: :* . : *: ***: .::.* :: *. ", "identical_positions": 206, "similar_positions": 115, "identity": "33.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101203-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97817-1", "uniprot_id": "CDR2_MOUSE", "id": "P97817-1", "name": "Cerebellar degeneration-related protein 2", "aln": "MLADNLVEEFEME-DEPWYDHRDLQQDLQLAAELGKTLLDRNTELEDSLQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVAESKASQQKILSLTETIECLQTNIDHLQSQVEELKSSSQGR--------GRQKACDQEKPAPSFSCLKELYDLRQHFVYDHVFAEKITSLQSQQSPDEEENEHLKKAVTMLQAQLSLERKKRVSVEAEYK---------------------------------VVLKENSELEQQLGATDAYRARALELEAEVAEMRQMLQAEHPFVN-GVEKLVPDSLFVPFKEPSQSLLEEMFLAAPEAPRKPLK-RSSSETALSSLAGDD------------IVKDHEDTCIRRAKAVKQRGISLLHEVD----------------------------TQYSALKVKYEELLKKCQQEQ-------------DSLSHKAVQTSRLLTRDLTGLVTQSEAGASGWEPTP-------------VSPESISSPTTTPPEYKALFKEIFSCIKKTKQEIDEQRTKYPSLSSYSY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01850-1", "uniprot_id": "CDR2_HUMAN", "id": "Q01850-1", "name": "Cerebellar degeneration-related protein 2", "aln": "MLAENLVEEFEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGR--------RSPGKCDQEKPAPSFACLKELYDLRQHFVYDHVFAEKITSLQGQPSPDEEENEHLKKTVTMLQAQLSLERQKRVTMEEEYG---------------------------------LVLKENSELEQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVN-GVEKLVPDSLYVPFKEPSQSLLEEMFLTVPESHRKPLK-RSSSETILSSLAGSD------------IVKGHEETCIRRAKAVKQRGISLLHEVD----------------------------TQYSALKVKYEELLKKCQEEQ-------------DSLSHKAVQTSRAAAKDLTGVNAQSEPVASGWELAS-------------VNPEPVSSP-TTPPEYKALFKEIFSCIKKTKQEIDEQRTKYRSLSSHS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F704-1", "uniprot_id": "E7F704_DANRE", "id": "E7F704-1", "name": "", "aln": "MLTDMIEGEFDMKEEEPWYDQQDLEHDLHLAAELGKNLLEQNRELEETIQQMYITNQEQMQEIEYLSKQVDLLRSVSDQHAKLYEQLDASSQELELKNQKLTQENRAAQIKIQGLTETVDGLQTHVEELQTDLQKMKQIAEEHKLCRSLRDDQRGKCASRRSCVSQESWVCSRRCSEPQEQREELQRSLHSLQAQLRSECALRESAELQVEDLMLQIRLLEPRAALVEEYEERLQEVQAEAQELRLHSSTHTPSLEEGGAWQKGWSLHQDMSLLDNEVGVVELRGRRLPILDDEVGVLAQIDDEVGVVGQRGWSLPMPDDEVGVVKQKGRRLHKDMSMLDYEVGVVQQKGRSLKHQALSLLADEVGVMGQNLQQSWCLLDEEVDVVGQSGRNLQHQGGSLLNDGVGVVTQSGGGLYQGVYLDEWDVVGHSGRSLQHQAASIQDDEVRVVSPSGRGLHNGMPLLDDGVGVVKHRGRGLQHQGASLLSEVDAQYVALQEKYDALLRRCQSDTPTHNQNTVPTHTHSTHNQQPEYKALFQEIFTFIQKSKEDLKENRTKPDQADCK--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:: : **:*: :*****::**::**:*******.**::* ***:::**** *****:******:***:***.:.:****:*****.:::*** .****. :.:*:* ** .****:: ***:::.**::::::*. .: : * ..:.. * . : . : ..: ***.* .: .* : * * *: * . : . :* : :: * *::::*.. * *: **. : *: : . : * . :**. .*: .: * ::* : * * ** .. ** **.. ::. . :. : .: ::::* ***:: *:.* .:: :*: . . : . :.*:. .: : *: : :* . . :: . * *. . *******:***: *:*:*:::.*:*** . .. ", "identical_positions": 141, "similar_positions": 159, "identity": "24.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101203-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97817-1", "uniprot_id": "CDR2_MOUSE", "id": "P97817-1", "name": "Cerebellar degeneration-related protein 2", "aln": "MLADNLVEE-FEME-DEPWYDHRDLQQDLQLAAELGKTLLDRNTELEDSLQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVAESKASQQKILSLTETIECLQTNIDHLQSQVEELKSSSQGRGRQKACDQEKPAPSFSCLKELYDLRQH--FVYDHVFAEKITSLQSQQSPDEEE-NEHLKKAVTMLQAQLSLERKKRVSVEAEYKVVLKENSELEQQLGATDAYRARALELEAEVAEMRQMLQAEHPFVNGVEKLVPDSLFVPFKEPSQSLLEEMFLAAPEAPRKPLKRSSSETALSSLAGDDIVKDHEDTCIRRAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQQEQDSLSHKAVQTSRLLTRDLTGLVTQSEAGASGWEPTPVSPESISSPTTTPPEYKALFKEIFSCIKKTKQEIDEQRTKYPSLSSYSY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01850-1", "uniprot_id": "CDR2_HUMAN", "id": "Q01850-1", "name": "Cerebellar degeneration-related protein 2", "aln": "MLAENLVEE-FEMKEDEPWYDHQDLQQDLQLAAELGKTLLDRNTELEDSVQQMYTTNQEQLQEIEYLTKQVELLRQMNEQHAKVYEQLDVTARELEETNQKLVADSKASQQKILSLTETIECLQTNIDHLQSQVEELKSSGQGRRSPGKCDQEKPAPSFACLKELYDLRQH--FVYDHVFAEKITSLQGQPSPDEEE-NEHLKKTVTMLQAQLSLERQKRVTMEEEYGLVLKENSELEQQLGATGAYRARALELEAEVAEMRQMLQSEHPFVNGVEKLVPDSLYVPFKEPSQSLLEEMFLTVPESHRKPLKRSSSETILSSLAGSDIVKGHEETCIRRAKAVKQRGISLLHEVDTQYSALKVKYEELLKKCQEEQDSLSHKAVQTSRAAAKDLTGVNAQSEPVASGWELASVNPEPVSSP-TTPPEYKALFKEIFSCIKKTKQEIDEQRTKYRSLSSHS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FC97-1", "uniprot_id": "E7FC97_DANRE", "id": "E7FC97-1", "name": "", "aln": "MLTDVIVEEDFDRSEEELWYSRKDLEHDLHLAAELGKTLLDRNHELEQGLQQMYSTNHEQLQEIEYLTKQVDLLRQMNDQHAKVYEQLDLAARDLEKSNQRLVLENRTSQHRIQSLTETIDGLQAHMESLQKQVDELKAS-QSRRDFTAARRALGAQSMSCLKEIYDLQQDKSWTSEGLHEERSWPVLSERCVEEEEETSTLQHSLHKLKQQLATERARRVEAERETELTVLENSALEDRLSLLEGARRRQAELEAEVEELRLLWRSESSSSRLTDTLLPDSVFFSAEERLG--VEPECEEEAEFPQG-RCRCSSDSYVRGARAEEIRRGHERSCIRRAQAVKQRGISLLNEVDAQYSALQLKYEELLRRCQHGANSLSHKAVQTPKSQSCSATDTACLSDQLHQ-------------------PEYKALFKEIFTCIQKTKEDLSENR----ALQAQ--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:: :*** *: . :* **.::**::**:************* ***:.:****:**:*************:******:**********::**:**::**:** :.::**::* ******: **:::: **.**:***:* *.* . : * *::****:***:*. :. : :. *: .: .: . :*** .. *:::: *: **: ** :** * * :.: *** **::*. . * * ****** *:* : ::* . . .:.*:***::.. :* :* .* : *.**:: : . ..:* :.** :*****:**********:***:*****::******::**. :*********.: : . *. *: . ***********:**:***:::.*:* :*.: ", "identical_positions": 208, "similar_positions": 130, "identity": "45.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101203-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NHV5-1", "uniprot_id": "MOSMO_HUMAN", "id": "Q8NHV5-1", "name": "Modulator of smoothened protein", "aln": "MDKLTIISGCLFLAADIFAIASIANPDWINTGESAGALTVGLVRQCQTIHGRDRTCIPPRLPPEWVTTLFFIIMGIISLTVTCGLLVASHWRREATKYARWIAFTGMILFCMAALIFPIGFYINEVGGQPYKLPNNTVVGSSYVLFVLSIFFTIVGLLFAGKVCLPG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QJW0-1", "uniprot_id": "F1QJW0_DANRE", "id": "F1QJW0-1", "name": "", "aln": "MDKLTIISGCLFLAADIFAIASIANPDWINTGESAGALTVGLVRQCQTIHGRDRTCIPPRLPPEWVTTLFFIIMGIISLTVTCGLLVASHWRREATKYARWIAFTGMILFCMAALIFPIGFYINEVGGQPYKLPNNTVVGSSYVLFVLSIFFTIVGLLFAGKVCLPG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8C784-1", "uniprot_id": "MOSMO_MOUSE", "id": "Q8C784-1", "name": "Modulator of smoothened protein", "aln": "MDKLTIISGCLFLAADIFAIASIANPDWINTGESAGALTVGLVRQCQTIHGRDRTCIPPRLPPEWVTTLFFIIMGIISLTVTCGLLVASHWRREATKYARWIAFTGMILFCMAALIFPIGFYINEVGGQPYKLPNNTVVGSSYVLFVLSIFFTIVGLLFAGKVCLPG", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***********************************************************************************************************************************************************************", "identical_positions": 167, "similar_positions": 0, "identity": "100.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101207-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JXI7-1", "uniprot_id": "A0A0G2JXI7_RAT", "id": "A0A0G2JXI7-1", "name": "", "aln": "MMVESASETIRSAPSGQNGVGSLSAQADGGGGAGTAGTAPAAGRDASGREAASG-ADSNGEMSPAELLHFQQQQALQVARQFLLQQASSLNSPGNNDSKQSASAVQVPVSVAMMSQQMLTPQQMQQILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLSQQQAGKQQPKE--ALGNKQLAFQQQLLQMQQLQQQHLLNLQRQGLVSLQPSQASGPLQALPQAAVCPTDLPQLWKGEGAPGQPAEDGGRQEGLDLASPAATATSFASPPKVSPPLSHHPLPNGQPTVLTSRRD--------------------------------SSSHEETPSSHPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLEIQLAKESERLQAMMAHLHMRPSEPKPFSQPLNPVPG--------SSSFSKVTVSA-DPFPDGLVHPPTSAAAPVTPLR--PPGLGSASLHGGGPARRRSNDKFCSPISSELAQNHEFYKNADVRPPFTYASLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEREYQKRRPPKMT------GSPTLVKNMISGLSYGALNASYQAALAESSFPLLSSPGMLN--PGSASSLLPLSQDDMGAPGEPLPSNGSSSPPRLSPPQYSHQIQVKEEPAEAEEDRRPGPPLGAPNPSTVGPPEDRDLEEDLAGEDMS---------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DBY0-1", "uniprot_id": "FOXP4_MOUSE", "id": "Q9DBY0-1", "name": "Forkhead box protein P4", "aln": "MMVESASETIRSAPSGQNGVGSLSAQADGGGGAGTAGTAPAAGRDASGREAASGGADSNGEMSPAELLHFQQQQALQVARQFLLQQASSLNSPGNNDSKQSASAVQVPVSVAMMSQQMLTPQQMQQILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLTQQQAGKQQPKE--ALGNKQLAFQQQLLQMQQLQQQHLLNLQRQGLVSLQPSQASGPLQALPQ-AVCPTDLPQLWKGEGAPGQPAEDSGRQEGLDLASTAVTATSFASPPKVSPPLSHHPLPNGQPTVLTSRRD--------------------------------SSSHEETPSSHPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLEIQLAKESERLQAMMAHLHMRPSEPKPFSQP--------------------VTVSA-DPFPDGLVHPPTSAAAPVTPLR--PPGLGSASLHSGGPARRRSNDKFCSPISSELAQNHEFYKNADVRPPFTYASLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEREYQKRRPPKMT------GSPTLVKNMISGLSYGALNASYQAALAESSFPLLSNPGMLN--PGSASSLLPLSQEDLGVPGEPLPSNGSSSPPRLSPPQYSHQIQVKEEPAEAEEDRRPGPPLGAPNPSTVGPPEDRDLEEDLGGEDMPSQPCPLIPGWKPSLLHLSYCVKPKFTVSVGSKTPSSPLPPPPRVQGSYSLPPCSYLAYGDMRGQNPAPSPGLLSGVGGGLFRCLHRTKSPSLPGVWILAAELETMRFHRPPMGDPQPKTADWV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IVH2-1", "uniprot_id": "FOXP4_HUMAN", "id": "Q8IVH2-1", "name": "Forkhead box protein P4", "aln": "MMVESASETIRSAPSGQNGVGSLSGQADGSSGGATGTTASGTG-----REVTTG-ADSNGEMSPAELLHFQQQQALQVARQFLLQQASGLSSPGNNDSKQSASAVQVPVSVAMMSPQMLTPQQMQQILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLTQQQAGKPQPKE--ALGNKQLAFQQQLLQMQQLQQQHLLNLQRQGLVSLQPNQASGPLQTLPQAAVCPTDLPQLWKGEGAPGQPAEDSVKQEGLDLTGTAATATSFAAPPKVSPPLSHHTLPNGQPTVLTSRRD--------------------------------SSSHEETPGSHPLYGHGECKWPGCETLCEDLGQFIKHLNTEHALDDRSTAQCRVQMQVVQQLEIQLAKESERLQAMMAHLHMRPSEPKPFSQPLNPVPG--------SSSFSKVTVSAADSFPDGLVHPPTSAAAPVTPLR--PPGLGSASLHGGGPARRRSSDKFCSPISSELAQNHEFYKNADVRPPFTYASLIRQAILETPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEREYQKRRPPKMT------GSPTLVKNMISGLSYGALNASYQAALAESSFPLLNSPGMLN--PGSASSLLPLSHDDVGAPVEPLPSNGSSSPPRLSPPQYSHQVQVKEEPAEAEEDRQPGPPLGAPNPSASGPPEDRDLEEELPGEELS---------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BDN3-1", "uniprot_id": "A0A8M3BDN3_DANRE", "id": "A0A8M3BDN3-1", "name": "", "aln": "MMVESATETIRTTPSNQNGVSSLSSQSDGGG-----------------REGGSN-GDTNGEISPVDLLHLQQQQALQAARQFILQQATGLNSPSSNEVKQ--SPVQVPVSMAMMTPQMITPQQMQQILSPPQLQALLQQQQALMLQQLQEYYKKQQEQLHLQLLTQQQQAGKQAKEQQQLGNKQLAFQQQLIQMQQLQQQHILNLQRQGLVNLQPGQGAVPIQSLQQ-AMCPTDLQQLWKDVAG-VQSTEEVMKHEGLDLTTNSSNTTSYSAS-KVSPQIPHHPLPNGQNSVHTPKRDRARLFEWISSFTKESSDEHLTPYSKGTPLQSTHSTHEEHTASHPLYGHGECKWPGCEALCEDMGQFIKHLNSEHALDDRSTAQCRVQMQVVQQLEIQLAKESERLQAMMAHLHMRPSEPKHFNQPLN------------LASSVSLSKRENDGFPEGLPHPPTSAATPITPMRQGPSVISSSSLHGVGPIRRRNSDKFCTPIASELAQNCEFYKNADVRPPFTYASLIRHAILEAPDRQLTLNEIYNWFTRMFAYFRRNTATWKNAVRHNLSLHKCFVRVENVKGAVWTVDEVEYQKRRPPKMTGYVDFKGSPTLVKNMISGLGFGSLNASYQAALAESSLGLLNSPTLMNNSTGASLNMLHIGHDDVSSTVEQVNSNGSCSPG-LSPHQYGHQIHVKEEPAEMEEDSRPVSLLASVTQNLSMPSDDRDMEDELPTEELE---------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K6N2-1", "uniprot_id": "A0A0B4K6N2_DROME", "id": "A0A0B4K6N2-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------MHRIHDDEYSEDAKESDFKSSIQKEISVKSRHQISIPDICSDAVKNNCFPPTGFLNNSITFASHVVK---CSSPASSIDESSTAAQQHESNPHMHIQGQHMMAPVPDLGFYNVPEFIS-----EQEKLMFSDAERFLRSKDNEVCNNDFSYMHDEFAMR---------------------------------------------------------------------KYYHPLFAHGICRWPGCEMDLEDITSFVKHLNTEHGLDDRSTAQARVQMQVVSQLESHLQKERDRLQAMMHHLYLSKQLLSPTKIDRKDVPGREGKFCRSPLTVNSIGRPIRQTNSPSPLNLPMVNSTNLCSIKKRNHDKNTFSINGGLPYMLERAG---LDVQQEIHRNREFYKNADVRPPFTYASLIRQAIIDSPDKQLTLNEIYNWFQNTFCYFRRNAATWKNAIRTNLSLHKCFVRYEDDFGSFWMVDDNEFVKRR-------------------HLSRGRPRKYEPSSSPNSCQSGNGVPTDKNPCDNCTQHCTSLPPGADN-------PLDSNNPNDLGRIGCLPYCGSDGLSKASKDYSN---MDSGMIESNSHLTIDEYSTNMYESSANEHNR---------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : .:: *. * : ::.:: : : :: . *:: :*.:. : : .. ::::. ** :.: :::* * :: *. . : : . : ::.. :. :: ::.:. ***:.** *:***** **: .*:****:**.********.*******.*** :* ** :****** **:: . . . : : . . : * :: : .:: .: *::. * . . : .*: :* *******************:**:::**:*********** . *.*****:******:* ********** *: *:.* **: *: *** :* :.* .. .:*. : .. : . . .: ..: : **.. . :. * . :.: . : .: . : . . :: :. *. ", "identical_positions": 136, "similar_positions": 155, "identity": "15.8%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101208-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PD28-1", "uniprot_id": "2A5B_MOUSE", "id": "Q6PD28-1", "name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform", "aln": "MET--KLPPASTPTSPSSPGLSPVPPPDKVDGFSRRSLRRARPRRSHSSSQFRYQSNQQELTPLPLLKDVPASELHELLSRKLAQCGVMFDFLDCVADLKGKEVKRAALNELVECVGCTRGVLIEPVYPDIIRMISVNIFRTLPPSENPEFDPEEDEPNLEPSWPHLQLVYEFFLRFLESPDFQPSVAKRYVDQKFVLMLLELFDSEDPREREYLKTILHRVYGKFLGLRAYIRKQCNHIFLRFIYELEHFNGVAELLEILGSIINGFALPLKTEHKQFLVRVLIPLHSVKSLSVFHAQLAYCVVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVMFLGEMEEILDVIEPSQFVKIQEPLFKQVARCVSSPHFQVAERALYFWNNEYILSLIEDNCHTVLPAVFGTLYQVSKEHWNQTIVSLIYNVLKTFMEMNGKLFDELTASYKLEKQQEQQKAQERQELWRGLEELRLRRLQG-TQGAKEAPVPRPTPQVAASGGQS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15173-1", "uniprot_id": "2A5B_HUMAN", "id": "Q15173-1", "name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform", "aln": "MET--KLPPASTPTSPSSPGLSPVPPPDKVDGFSRRSLRRARPRRSHSSSQFRYQSNQQELTPLPLLKDVPASELHELLSRKLAQCGVMFDFLDCVADLKGKEVKRAALNELVECVGSTRGVLIEPVYPDIIRMISVNIFRTLPPSENPEFDPEEDEPNLEPSWPHLQLVYEFFLRFLESPDFQPSVAKRYVDQKFVLMLLELFDSEDPREREYLKTILHRVYGKFLGLRAYIRKQCNHIFLRFIYEFEHFNGVAELLEILGSIINGFALPLKTEHKQFLVRVLIPLHSVKSLSVFHAQLAYCVVQFLEKDATLTEHVIRGLLKYWPKTCTQKEVMFLGEMEEILDVIEPSQFVKIQEPLFKQVARCVSSPHFQVAERALYFWNNEYILSLIEDNCHTVLPAVFGTLYQVSKEHWNQTIVSLIYNVLKTFMEMNGKLFDELTASYKLEKQQEQQKAQERQELWQGLEELRLRRLQG-TQGAKEAPLQRLTPQVAASGGQS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q9Y3-1", "uniprot_id": "F1Q9Y3_DANRE", "id": "F1Q9Y3-1", "name": "Serine/threonine protein phosphatase 2A regulatory subunit", "aln": "METPTKLPPSS-PSSPTT-GFS-VPSAEKVDGFPRRSMRRARQRRSHSSSQFRYQSSQVELTPLPLLKDAPVAELHDLFCKKLQQCCVLFDFLDCVADLKGKEIKRAALNELVESVATSRGVLIEPLYPEAIKMISVNIFRTLPPSENPEFDPEEDEPALEASWPHLQLVYEFFLRFLESPDFQPSLAKRYVDQKFVLQLLELFDSEDPREREYLKTILHRVYGKLLGLRAYIRKQINNIFLRFIYETERFNGVAELLEILGSIINGFALPLKSEHKQFLVRVLIPLHTAKSLSIFHAQLAYCVVQFMEKDATVTEHIIRGLLRYWPKTCTQKEVMFLGEIEEILDVIEPSQFIRVQEPLFKQIAACISSPHFQVAERALYFWNNEYILSLIEENCQVILPLVFGTLYRVSKEHWNQTIISLIYNVLKTFMEMNSKLFDDLTASYKVEKQKELKKERERVELWRNLEDLRERRLQSLTEASRNQKNLQERENTAKSQSDTSAANTT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ****:* *:**:: *:* **..:*****.***:**** *************.* **********.*.:***:*:.:** ** *:**************:**********.*. :*******:**: *:************************* **.************************:*********** **************************:********** *:******** *:***********************:**************:.****:************:*****:***:*****:****************:************:::*******:* *:*************************:**:.:** ******:**********:**************.****:******:***:* :* :** ***:.**:** ****. *:.::: : :.* * .:: ", "identical_positions": 397, "similar_positions": 72, "identity": "78.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101208-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZPN5-1", "uniprot_id": "D3ZPN5_RAT", "id": "D3ZPN5-1", "name": "", "aln": "MLAQKPADLWRLLPAAVTMAARGVGLLTRLPLCSQRRSRVPHSISRHLSCPGTRVASVGSEEQPSGGAETGTEDKTLQKKFSEVQKERREQAQRTVLIHCPNNINEKKFLKYLSQHGSIS--NHFFYESFGLYAVVEFCQKDSINSLQNGTHTPTQSTEAAIPFKSRFLNLKLKNPS------NQVSGQSFVQADSQSPPSSKKLFELLSYAESIDAQLTALLKAFQLTEENVRLRHLTCSLIEDIAAAYFPSCVVWPFGSSVNTFGKLGCDLDMFLDLDETG--NLSDHKNTGNFLMEFQVKNVPSERVATQKILSVIGECLDNFGPGCVGVQKILNARCPLVRFSHQGSGFQCDLTANNSIALKSSELLYIYGSLDSRVRALVFGVRCWARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSLKSMADAED-RCILEGNNCTFIQDINKIKP-SGNTETLELLLKEFFEYFGNFAFNKNSINIRQGREQNKPDSSPLYIQNPFETSLNISKNVSQNQLQKFVELARDSAWILEQEKKDQP----SSSS-HPWGLAALLLPPG-------------------------AGQTSLS--RKKKKKPMSEKVKGLLASIKSNSPDRSTDASGKRAVSTQA---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D0D3-1", "uniprot_id": "PAPD1_MOUSE", "id": "Q9D0D3-1", "name": "Poly(A) RNA polymerase, mitochondrial", "aln": "------------------MAARGVGLLTRLPVCSQRRNRIPRSISRLLSCPGTIAASIGSEEQSSVVAETGIEDKTLQKKFSEVQKERREQAQRTVLIHCPNNINEKKFLKYLSQHGPVN--NHFFYESFGLFAVVEFCQKDSIKSLQNGTHTPTQSTEAAIPFKSRFLNLRLKNPS------SQVSGQPFVQTTNQSPPSSKKLFELLSYAESIEEQLNTLLKAFQLTEENIRLRHLTCSLIEDIAAAYFPSCVIRPFGSSVNTFGKLGCDLDMFLDLDETG--KLDVHKNTGNFFMEFQVKNVPSERIATQKILSVIGECLDNFGPGCVGVQKILNARCPLVRFSHQGSGFQCDLTANNSIALKSSELLYIYGSLDSRVRALVFSVRCWARAHSLTSSIPGAWITNFSLTVMVIFFLQRRSPPILPTLDSLKSIADAED-RCILEGNNCTFVQDVNKIQP-SGNTETLELLIKEFFEYFGNFAFNKNSINIRQGREQNKPDSSPLYIQNPFETSLNISKNVSQSQLQKFVELARDSAWILEQEDKNQP----FSSSRQPWGLAALLLPPG-------------------------SGHTSLS--RKKKKKPMSEKVKGLLASIKSNSPDSSTDTSGKRTISTQA---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVV4-1", "uniprot_id": "PAPD1_HUMAN", "id": "Q9NVV4-1", "name": "Poly(A) RNA polymerase, mitochondrial", "aln": "------------------MAVPGVGLLTRLNLCARRRTRVQRPIVRLLSCPGTVAKDLRRDEQPSGSVETGFEDKIPKRRFSEMQNERREQAQRTVLIHCPEKISENKFLKYLSQFGPIN--NHFFYESFGLYAVVEFCQKESIGSLQNGTHTPSTAMETAIPFRSRFFNLKLKN---------QTSERSRVRSSNQLPRSNKQLFELLCYAESIDDQLNTLLKEFQLTEENTKLRYLTCSLIEDMAAAYFPDCIVRPFGSSVNTFGKLGCDLDMFLDLDETR--NLSAHKISGNFLMEFQVKNVPSERIATQKILSVLGECLDHFGPGCVGVQKILNARCPLVRFSHQASGFQCDLTTNNRIALTSSELLYIYGALDSRVRALVFSVRCWARAHSLTSSIPGAWITNFSLTMMVIFFLQRRSPPILPTLDSLKTLADAED-KCVIEGNNCTFVRDLSRIKP-SQNTETLELLLKEFFEYFGNFAFDKNSINIRQGREQNKPDSSPLYIQNPFETSLNISKNVSQSQLQKFVDLARESAWILQQEDTDRP----SISSNRPWGLVSLLLPSA-------------------------PNRKSFT--KKKSNKFAIETVKNLLESLKGNRTENFTKTSGKRTISTQT---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40E6A7-1", "uniprot_id": "A0AB40E6A7_DANRE", "id": "A0AB40E6A7-1", "name": "", "aln": "-----------------MAASLGVCRLHFRSLGGLDRFCLGLEPQTQRRCTSTIPA----IKTPTGSKTADFVKKS--KTFQAIQEERREQAERSVLISCPAKFSEKKFLDFFSKHGTVN--KHFFYNSFGAYAVVEFSNKESIASLKESTGIPAVDHEAAVPFKSRLLSLKWPG--------IQSSNYPTPNFKEQSPPNIGDISNLLLQKHSVDEQLRCLTETLQLTEENISLRFLVCSLLGDIAGAYFPECIIRPFGSTVNSFGKLGCDVDMILDLDGIY--ARSQKKGSG-LSLEYQVKTGPSERAVTQSILSVVGKCVDQFGPGCVGVQNILQARCPIVRFAHQPSGFQCDLTANNKVAMKSSELLFLYGHLDPRVRHLVFSVRCWARAHSITSSIPGAWITNFSLTVMVVFFLQQRSPAMLPTLDRLKELAGPSD-KCVIEGNDCTIVSDLSKIAL-QKNTDTLEKLLQEFFEFYGNFPFNKASINIRKGKEQSKPEAAALHIQNPFEATLNVSKNVNAAQLERFVKLCQESAWLFQQKENLEPGSTQSNGSVSPWGFAALLAPSV-------------------------ASGTGVKSRRKKKTEPASSRIKNLLDSLKIKGGETVAKKGSANSSR------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O46102-1", "uniprot_id": "PAPD1_DROME", "id": "O46102-1", "name": "Poly(A) RNA polymerase, mitochondrial", "aln": "--------------------MNSLVRRSAQQLSLWRTYCIKHNASEAASPG----------------------RNAGRPNYEEFIGRHQRQAQCSIVVQVSSEKSYEELYNYCSSFGSIMGAHHYCVRQDETLHYILLEYATSDEAAAAIGAGVTNGELSGVPVRSPFLWFRAAGGGRRSPKLVANTAPALLSLDGTRQVDQRHLLGLLRGAADIEEQVQQLYEHTRLNELGIRMRFLAALQVQQAIAGMFPAAQAQPFGSSVNGFGRMGCDLDLILRFDSDMGAKIPLEAAVPSRLVYHTKENLSNGRSQTQRHMECFGDMLHLFLPGVCHVRRILQARVPIIKYHHEHLDLEVDLSMSNLTGFYMSELLYMFGEMDPRVRPLTFTIRRWAQTCGLTNPSPGRWISNFSLTCLVMFFLQQLRQPILPTIGALAKAAEPGDSRVTEDGINCTFTRNVDRLGFRSRNQSSLSELLLQFFEFYSQFDFHNRAISLNEGKPLSKPDHSAMYIVNPLEQLLNVSKNVSLEECERLRIEVRNAAWVLESEVENASVP-EGDGQELSCGLLNLFKHPEKAVIRPNMFFKPRMVEVSDLFEQKEAGATSSSTPPTPAITYKSASVRQQVQSIKAATRSELKQLRGSGSSVPTSSPNNRRRSR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : : : :. . .::.**: :::: . : . ::: .: *..*.: :*: .. : : * : : :.:*.:* :: :: . : . . .: ** .:: *: * : :*.* . :*.*.. : : .. ** . ****:** **::***:*::* :* . : . :. .. * ** :. .*. :. * ** *:.**:** *:::: *: .:: **: .* .: ****:::* :*.*** *.* :* **:: .:*.. ** **:***** :*:****: .:***:. * * . * : :* :**: ::.:: . * .:*. *: :***::.:* *.: :*.:.:*: .**: :.::* **:* **:****. : ::: :::**:::.: . .. . *: *: . .. .. . . :: : *:* . . . : ", "identical_positions": 115, "similar_positions": 195, "identity": "17.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101216-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K0N1-1", "uniprot_id": "A0A0G2K0N1_RAT", "id": "A0A0G2K0N1-1", "name": "X-ray radiation resistance-associated protein 1", "aln": "MRLSGPKCCVLRREVKRQVKKQKQKEGKESLPKSKIREMVSSGIYKMDNGKPCLNNCFPAKSLLRLPEEGRGHWLVARKGSMKK---GVAKASTEGQENQKKVSFDTGLKKISRRDSQAEIGGHILDRSFLLKHHSARKPSELCTINVSGMKFSKAKEKDFKHFTSVIYINASENLLPLDVFHTFPTLKELELAFNGIKMVYVKYGDFKTLEFLDLSFNSLTEEAICDLGILPHLRVLLLTGNGLTSLPPNMAVKEQEASVTSLTSKKYILRFPALETLMLDDNKLSNPSCFASLAGLRRLKKLSLDQNKIFRIPYLQQVQLRDGTGDWVTEGPNSQKE----LQPQMWIFETPDEQPNYTVLPMKKDVDRTEVVFSSYPGFSTSETTKVCSLPPIFEILPVKSLKARNQTLAPPFPELRYLSLAYNKIAKEDAVLPAALFPSLCELIFHNNPLVAHTRGIPPLLKSFLQDRLGIRLVRKKLVKPKHHMLMPRKESRKVKTYIPKVSKHSLVPHHLSTITDNRPSSLLPEPE-------LSTENTSHEALFTNEGPEGPPVTHRAFVPMPPICSDSTVHS-DIVSHQSRTAGLMSPEHPSDDDAKSTESIFLTQVNELPSSTVHRDNLEAEESHQRRPSTAPRETKRTRRKQTATSLHNKYDGYEELLTVKPDPAFVEPKGIQKNAQALHRMLKQPLICRSSKPRLDTFQKPYIPKEKRVARIPIPPPRKTRAQLLDDILIRMRDPRNVTEAPLGAVLQRRGQQRLVNQKQYREAKRLLKEFRARYRQLVRSSLRTVFTSSPPPRPPTRRALSAGQPKLGRFLEFMDEFCQEPTAGDSKE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U3V8-1", "uniprot_id": "XRRA1_MOUSE", "id": "Q3U3V8-1", "name": "X-ray radiation resistance-associated protein 1", "aln": "--------------------------------------MVSSGMYKMDNGKPCLNNCFPAKSLLRLPEEGRGHWIVVRKGSMKK---GAAKASTEGQESQKKVSFDTGLKKISRRDSQADVLGHILDRSFLLKHHSARKPSDLCTINVSGMKFSKAKEKDFKHFTSVIYINASENLLPLDVFHTFPVLKELELAFNGIKMVYVKYGDFKTLEFLDLSFNSLTEEAICDLGILPHLRVLLLTGNGLTSLPPNMAVKEQEASMTSLTSKKYILRFPALETLMLDDNKLSNPSCFASLAGLRRLKKLSLDQNKIVRIPYLQQIQLRDGSGDWVTEGPNPQKE----LQPQMWIFETPDEQPNYTVLPMKKDVDRTEVVFSSYPGFSTSETAKVCSLPPMFEILPVKSLKARNQTLAPPFPELRYLSLAYNKIAKEDAVLPAALFPSLCELVFHNNPLVAHTRGIPPLLKSFLQDRLGIRLVRKKLVKPKHHMLMPRKESRKVKTYIPKVPKHSLVPHHLNMITDSPPSSLMPEPE-------HSTEDTSHEALFANEGPEGPSLTHRAFVPMPPICSDSTVHS-EAVSHQSHTAGLVSSEHPSDDDAKSTESIFLTQVNELPSSTAHRENLEAVN-DQRRPSTAPRETKRTRRKQTATSLHNKYDGYEELLTVKPDPAFLEPKGIQKNAQALHRMLKQPLICRSSKPRLDTFQKPYVPKEKRAGRIPILPPRKTRAQLLDDILIRMRDPRNVTEAPLGTVLQRRAQQRLVNQKQYREAKRLLKEFRARYRQLVRSSLRTVFAASPPPRPPTRRALSAGQPKLGRFLEFMDEFCQEPTASDSKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P2D8-1", "uniprot_id": "XRRA1_HUMAN", "id": "Q6P2D8-1", "name": "X-ray radiation resistance-associated protein 1", "aln": "--------------------------------------MAFSGIYKLDDGKPYLNNCFPARNLLRVPEEGQGHWLVVQKGNLKKKPKGLVGAQAERRESLKATSFEFKGKKESRRENQVDLPGHILDQAFLLKHHCVRKPSDLCTIN--------AKENDFKHFHSVIYINASENLLPLEAFHTFPALKELDLAFNGIKTIYVKYGDFKLLEFLDLSFNSLTVEAICDLGILPHLRVLLLTGNGLTSLPPNLAVAEQEASVTSLTSKRYILRFPALETLMLDDNRLSNPSCFASLAGLRRLKKLSLDENRIIRIPYLQQVQLYDESVDWNGGRGSPHKEPQFMLQSKPRMLEDSDEQLDYTVLPMKKDVDRTEVVFSSYPGFSTSETTKICSLPPIFEILPVKSLKARNQTLAPPFPELRYLSLAYNKIAKEDAVLPVALFPSLCEFVFHNNPLVAHTRGVPPLLKSFLQERLGIHLIRRKIVKPKHHVLMSRKESWKVKSEIPKVPKQPLVLHHPRMTTTKSPSKDMLEPEAELAEDLPTTKSTSVESEMPTENLEGHSPSCRTFVPLPPICSNSTVHSEETLSHLSDTTVRLSPERPSDEDSKSTESIFLTQVSELPSSVIHKDDLELKEKDQKKPPTAPREVKGTRRKLPTAFLPSKYHGYEELLTAKPDPAFIEPKGIQKNAQALQQMLKHPLLCHSSKPKLDTLQKPYVHKEKRAQRIPIPPPKKTRAQLLDDIFIRLRDPRNITEAPLGAVLHQWTERRLVNHKQYLEAKRLLKEFQARYRQLVSGSLRTVFGTTPLPMACP--ALSESQPKFGHFLEFMDEFCQEPTASDSQG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RFR4-1", "uniprot_id": "A0A8M1RFR4_DANRE", "id": "A0A8M1RFR4-1", "name": "", "aln": "--------------------------------------MAELGIYKLDNGRSYPSNCFPIRSFFLPRNEGAGHWLVAHRN--------ALEEEISKRKNISDLEVHFG------KEGKGVQASNTLEAQLLITLHCVDKPSDLCSVNISGQRLETVKLEGLEQFDNIAYINASDNHLTLEPFGRFPALRELELSLNSLHKLEIHADDFKKLEVLDLSFNNVTGESILNLGLLPCLKVLHLTGNQLQMLPLSMAG---SCNQLEENTDQGVSLFESLEVLMLDDNKLTSPGVFMSLANMKRLRHLNLQGNLISGVPFLEQMATLEDAQAGNIPQSILQNP--------------------SLINDKRRTYSEIKMIHKTIEKTLEEDKACLQMHLDHLKYLVQRKKDGSSLDQCLPFPELHHLNLANNEIAEEEALLPVALFPKLSELVIHSNPLTTQKSGDPPMLTSFLQDKLGIKITRKKTTDHVKQHICPKRKVKTTTSITPKLASIMASPLATKRVYS--------------------KKYTSEDCLLPSEYG-----LMHVFDLPSQISIKDEKDISIGQEHFDFTRAGLSFEMIQNE-----ESFFVTEVNELNESDYQKD-------------SYDAEETKLKVKKCSKACPEKLIGYEILLGDTSGPEMPETCGIQHAVNVLEHTLKNLLVYRDSKANVDIPQKLYIERERKIKNLPPLEPKKSRGKIVDGLLDQIKETKTISKYPLDNILKGGNK---VDKSEYNEALILLKDLKRKYSTAHLKRVEQAAQIETEKMCNVN-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. *:**:*:*:. .**** :.:: :** ***:*.::. . . ::. . ... ::.: .: *: :*:. *.. ***:**::* .* :.:::* .: *****:* *.*: * **.*:**:*::*.:: : :: .*** **.******.:* *:* :**:** *:** **** * ** .:* ... . .:.: : * :**.******:*:.*. * ***.::**::*.*: * * :*:*:*: : : :: : :: .. :::..: .:.: : :: * :. .. . . *****::*.** *:**:*:*:**.****.*.*:::*.***.::. * **:*.****::***:: *:* .. :: : .::: ...: **:.. .: ** :. :..* :.* . *. .. . .* . * :* * .:: **:*:*:*.** .* ::: : * . : * : .* *** ** ...* : *. ***: .:.*.: **: *: :.**..:* ** *: :*:: .:* *:*:*.:::*.:: ::::.:.::: **. :*: : *::.:* ** ***::: :* :. . . ", "identical_positions": 194, "similar_positions": 260, "identity": "23.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101220-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5TCZ1-1", "uniprot_id": "SPD2A_HUMAN", "id": "Q5TCZ1-1", "name": "SH3 and PX domain-containing protein 2A", "aln": "MLAYCVQDATVVDVEKRRNPSKHYVYIINVTWSDSTSQTIYRRYSKFFDLQMQLLDKFPIEGGQKDPKQRIIPFLPGKILFRRSHIRDVAVKRLKPIDEYCRALVRLPPHISQCDEVFRFFEARPEDVNPPKEDYGSSKRKSVWLSSWAESPKKDVTGADATAEPMILEQYVVVSNYKKQENSELSLQAGEVVDVIEKNESGWWFVSTSEEQGWVPATYLEAQNGTRDDSDINTSKTGEVSKRRKAHLRRLDRRWTLGGMVNRQHSREEKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKKAKDDLPTR-------KKNLAGPVEIIGNIMEISNLLNKKASGDKETPPAEGEGHE-------------------------APIAKKEISLPILCNASNGS-AVGVPDRTVSRLAQ-----------------GSPAVARIAPQRAQIS---SPNLRTRPPPRRESSLGFQLPKPPEPPSVEVEYYTIAEFQSCISDGISFRGGQKAEVIDKNSGGWWYVQIGEKEGWAPASYIDKRKKPNLSRRTSTLTRPKVPPPAPPSKPKEAEEGPTGASESQDSPRKLKYEEPEYDIPAFGFDSEPELSEEPVEDRASGERRPAQPHRPSPASSLQRARFKVGESSEDVALEEETIYENEGFRPYAEDTLSARGSSGDSDSPGSSSLSLTRKNSPKSGSPKSSSLLKLKAEKNAQAEMGKNHSSASFSSSITINTTCCSSSSSSSSSLSKTSGDLKPRSASDAGIRGTPKVRAKKDADANAGLTSCPRAKPSVRPKPFLNRAESQSQEKMDISTLRRQLRPTGQLRGGLKGSKSEDSELPPQTASEAPSEGSRRSSSDLITLPATTPPCPTKKEWEGPATSYMTCSAYQKVQDSEISFPAGVEVQVLEKQESGWWYVRFGELEGWAPSHYLVLDENEQPDPSGKELDTVPAKGRQNEGKSDSLEK-IERRVQALNTVNQSKKATPPIPSKPPGGFGKTSGTPAVKMRNGVRQVAVRPQSVFVSPPPKDNNLSCALRRNESLTATDGLRGVRRNSSFSTARSAAAEAKGRLAERAASQGSDSPLLPAQRNSIPVSPVRPKPIEKSQFIHNNLKDVYVSIADYEGDEETAGFQEGVSMEVLERNPNGWWYCQILDGVKPFKGWVPSNYLEKKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O89032-1", "uniprot_id": "SPD2A_MOUSE", "id": "O89032-1", "name": "SH3 and PX domain-containing protein 2A", "aln": "MLAYCVQDATVVDVEKRRSPSKHYVYIINVTWSDSTSQTIYRRYSKFFDLQMQLLDKFPIEGGQKDPKQRIIPFLPGKILFRRSHIRDVAVKRLKPIDEYCRALVRLPPHISQCDEVFRFFEARPEDVNPPKEDYGSSKRKSVWLSSWAESPKKDVTGADTNAEPMILEQYVVVSNYKKQENSELSLQAGEVVDVIEKNESGWWFVSTSEEQGWVPATYLEAQNGTRDDSDINTSKTGEVSKRRKAHLRRLDRRWTLGGMVNRQHSREEKYVTVQPYTSQSKDEIGFEKGVTVEVIRKNLEGWWYIRYLGKEGWAPASYLKKAKDDLPTR-------KKNLAGPVEIIGNIMEISNLLNKKASGDKEAP-AEGEGSE-------------------------APITKKEISLPILCNASNGS-ALAIPERTTSKLAQ-----------------GSPAVARIAPQRAQIS---SPNLRTRPPPRRESSLGFQLPKPPEPPSVEVEYYTIAEFQSCISDGISFRGGQKAEVIDKNSGGWWYVQIGEKEGWAPASYIDKRKKPNLSRRTSTLTRPKVPPPAPPSKPKEAEENPVGACESQGSPLKVKYEEPEYDVPAFGFDSEPEMNEEPSGDRGSGDKHPAQPRRISPASSLQRAHFKVGESSEDVALEEETIYENEGFRPYTEDTLSARGSSGDSDSPGSSSLSLAVKNSPKSDSPKSSSLLKLKAEKNAQAELGKNQSNISFSSSVTISTTCSSSSSSS--SLSKNNGDLKPRSASDAGIRDTPKVGTKKDPDVKAGLASCARAKPSVRPKPVLNRAESQSQEKMDISSLRRQLRPTGQLRGGLKGSRSEDSELPPQMASE----GSRRGSADIIPLTATTPPCVPKKEWEGQGATYVTCSAYQKVQDSEISFPEGAEVHVLEKAESGWWYVRFGELEGWAPSHYLVAEENQQPDTASKEGDTG--KSSQNEGKSDSLEK-IEKRVQALNTVNQSKRATPPIPSKPPGGFGKTSGTVAVKMRNGVRQVAVRPQSVFVSPPPKDNNLSCALRRNESLTATDSLRGVRRNSSFSTARSAAAEAKGRLAERAASQGSESPLLPTQRKGIPVSPVRPKPIEKSQFIHNNLKDVYISIADYEGDEETAGFQEGVSMEVLEKNPNGWWYCQILDEVKPFKGWVPSNYLEKKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B726-1", "uniprot_id": "A0ACD6B726_DANRE", "id": "A0ACD6B726-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------MARRSSGGHGRGGSWLTACFFPSSSGKERGEALGAEDCMCVYAVTADYQRQENTEISLKAGERVEVIEKSESGWWFVRTAEEQGWVPATYLVSLTGRRDS---HRAPNGET----------------------------EWYITVQPFSSSSQDELGFESGVIVEVIQRNLEGWWFIRYGGKEGWAPAAYLKKIQDGVTASNQPAESNKASVQGQVEIIGNLMEISNLLNKKPANERHSHTQTDSHSANTYRNSQTDSYTQYSGDEDQTEVNTERDSEDQIKTHIETSVSDSSGSVSVSDACVSAVATELCVSSTVSSFKAKTVPASPAIARVAPQRFHSVENKPPSNNLKPPPRRENSLGFQLPQPPDPPTVEAEYYTIAEFRSCLTDGISFSGGQRADVIEKNSGGWWYVQIGEKEGWAPCSYIDKRKKPTLNRQTSTLTRPKVPPPAPPIKKQNS--LPCVESEIMTTTYPRVYEEPEYDVPTIGFEFDPDLDFFPS----------DAPTKATPPLCQRTVSFTLGDEED-----DEGVYANGGFR--------AVPHCKDNHSP-SSAHRASMWDPPEYDAP-------------------------TIEPSFETNTTLYAQSNQP-------------------------KLKQQADE---------SKSKPSVRPKPTN----------QDCSSLR----------------KPQNQEQPSHMQFR----TSRTSEESDTGLSDDFQSCLS----DSSSFLYRTTAAYQQEEPCELSFPAGVQVEVVEKKESGWWFVRWGNEEGWAPTYYLQPIKSSSETSSLEAKTTEKINSELSWSASPELEISVQVDSGKMGKSVSLEKNEQRVNQSLKGGLRSNS-------RVGVKQLAVRPQNVLKDN--TNAHAAPAGRRNDTLPSHSSLVSYNDQSSSSHAG-----------------NTES-----MRRKVPVSMVKPKP----HLIHNNLREEYVSIADYRGDAETMSFPAGTRLEVLERNPNGWWYCRVLDTTKTRKGWVPSNFLERKS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:.. *. * . **:: ..... .:: . : *.*.::*::***:*:**:*** *:****.******* *:*********** : .* **. : : .**. * *:****::*.*:**:***.** ****::******:*** ********:**** :*.:.: * .: * ******:**********.:.::.: .. ::.:*. * ..*:.* ::.:.: .* :* .***:**:**** : .*. . :******.*******:**:**:**.********:**::***** ***:*:**:*******************.*********.*.*:*************** * ::: * .* :. *******:*::**: :*::. * * : :*. . : . *.:*:..: :* :* * *** * . *..** **: : :.*: .:* ::..*. .** :.*... *: : * .::******** * *:** :.::.* *.: . ** .. . *. .* . :. . * * :***: : .*:*** *.:*.*:** *****:**:*: *****::** :... .: : * :. . . * .** :: :.. . :: : .. **: ..* * **:*:*****.*: . .: : : * ***::*.: ..* . . :** * * .::* *. :*** *:*** ::*****:: *:*****.** ** .* *. :****:********::** .*. *******:**:*.", "identical_positions": 369, "similar_positions": 258, "identity": "31.09%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101220-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P40890-1", "uniprot_id": "VTH2_YEAST", "id": "P40890-1", "name": "VPS10 homolog 2", "aln": "MALFRALYIIWVFLLIPLSNAEEFTPKVTRTLSRYVFDIVNFDDSNTLIRAEEDSVEISFDAGENWKTIDEIEEPIESFVVDPFRGHDRAFAFVKTAPKFYVTDDQGKSWRPLTIPIS-EKASNYFCDVTTHPIKKKHLIIRCDLLTIKNSG------------------LMYVGREIYTTNDG-VSFSQVKPSFGKIDG-HISTARCDFIKSSEDSDLGGNDASILCLFRNTEYIESTG-STIDKSELILSADGGETFKELVQFKDKVVSRYEILKHHVIVLTQDDMYNEMSSTNIWISNDVSTFQVARTPTKIRHVNMGQIHEDSIGRIVLPVSRERDDEDSNQPGAAEVLISDSEGLKFLPINWIPNNQFGYINVAYPGFLKGTFFGSFHPFIEYSDRKRKYSRQKVREETKVSVDNGLTWTNLKVVDRENVDLFGCDVTKPERCSLQTHFYDLRNLNPSAGIMMISGIVGDGSAYNWKEEKTFISRDSGLTWRLVHNSTGLYTTGDLGNIIMYIP--YRSNENGDVPSKFYYSLDQGKTWGEYDL---IMPIYPYRLVSTISDGSGSKFILTG-TSITEDPIF--------ITYSIDFSAVFDYKSCEEGDFEDWNLADGKCVNGAKYKYRRRKQDAQCLVKKAFKDLS--LDETPCNSCTGSDYECSFEFVRDAKGDCIPDYNLIALSDICD-KSKGKSVLVKPLQLIKGDKCKTPMKIESVDIPCDEIPKEGSSDKEIVTTENKFDFEIKFYQYFDTVADESLVMLNSIGDAYISHDGGQTIKRFDTDGEKIVEIVFNPYFN---SSAYLFGSKGNIFLTHDRGYSFMIAKLPEARQLGMPLDFSAKAQDTFIYYGGKNCESILSPECHAVAYLTKDGGETFTEMLDNAIHCEFAGTLFKYPSNDDMVMCQVKEKFSQTRSLVSSTDFFQDDRKTVFENIIGYLSTGGYIIVAVPHEDNELRAYVTNDGAEFTEAKFPYDEDIGKQDAFTILGSEEGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKVQGLEGIIITNIVSNSEKVGENKEDEQLKTKITFNDGSDWNFLKPPKKDSEGKKFPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGDRLLPYEECSTFLTTDGGETWTEVKKGPHQWEYGDHGGVLVLVPENAETDSISYSTDFGKTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGRKRADFKYSPLGSRTGCLFGHKTEFLRKTDEKCFIGNIPLSEFSRNVKNCPCTRQDFECDYNFYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYRKIPLSTCKGGLKLDAHLAPHPCPGKEKAFREKYSINTGAYALVFVTILLVIFFVAWFVYDRGIRRNGGFSRFEEIRLGDDGLIENNRTDRVVNIIVR-LGLCISLITKSAFQRAKAGTAQLSSKFRARFGNKKGATYSSLLHDQLSDEPD----GFHEDSNDLSSFRGQGSNSEIEQEDVDTSQQEHTSRTDLLG----ASNIPDALPARS--ASHESDLAAARSEDK------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40438-1", "uniprot_id": "VTH1_YEAST", "id": "P40438-1", "name": "VPS10 homolog 1", "aln": "MALFRALYIIWVFLLIPLSNAEEFTPKVTRTLSRYVFDIVNFDDSNTLIRAEEDSVEISFDAGENWKTIDEIEEPIESFVVDPFRGHDRAFAFVKTAPKFYVTDDQGKSWRPLTIPIS-EKASNYFCDVTTHPIKKKHLIIRCDLLTIKNSG------------------LMYVGREIYTTNDG-VSFSQVKPSFGKIDG-HISTARCDFIKSSEDSDLGGNDASILCLFRNTEYIESTG-STIDKSELILSADGGETFKELVQFKDKVVSRYEILKHHVIVLTQDDMYNEMSSTNIWISNDVSTFQVARTPTKIRHVNMGQIHEDSIGRIVLPVSRERDDEDSNQPGAAEVLISDSEGLKFLPINWIPNNQFGYINVAYPGFLKGTFFGSFHPFIEYSDRKRKYSRQKVREETKVSVDNGLTWTNLKVVDRENVDLFGCDVTKPERCSLQTHFYDLRNLNPSAGIMMISGIVGDGSAYNWKEEKTFISRDSGLTWRLVHNSTGLYTTGDLGNIIMYIP--YRSNENGDVPSKFYYSLDQGKTWGEYDL---IMPIYPYRLVSTISDGSGSKFILTG-TSITEDPIF--------ITYSIDFSAVFDYKSCEEGDFEDWNLADGKCVNGAKYKYRRRKQDAQCLVKKAFKDLS--LDETPCNSCTGSDYECSFEFVRDAKGDCIPDYNLIALSDICD-KSKGKSVLVKPLQLIKGDKCKTPMKIESVDIPCDEIPKEGSSDKEIVTTENKFDFEIKFYQYFDTVADESLVMLNSIGDAYISHDGGQTIKRFDTDGEKIVEIVFNPYFN---SSAYLFGSKGNIFLTHDRGYSFMIAKLPEARQLGMPLDFSAKAQDTFIYYGGKNCESILSPECHAVAYLTKDGGETFTEMLDNAIHCEFAGTLFKYPSNDDMVMCQVKEKFSQTRSLVSSTDFFQDDRKTVFENIIGYLSTGGYIIVAVPHEDNELRAYVTNDGAEFTEAKFPYDEDIGKQDAFTILGSEEGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKVQGLEGIIITNIVSNSEKVGENKEDEQLKTKITFNDGSDWNFLKPPKKDSEGKKFPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGDRLLPYEECSTFLTTDGGETWTEVKKGPHQWEYGDHGGVLVLVPENAETDSISYSTDFGKTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGRKRADFKYSPLGSRTGCLFGHKTEFLRKTDEKCFIGNIPLSEFSRNVKNCPCTRQDFECDYNFYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYRKIPLSTCKGGLKLDAHLAPHPCPGKEKAFREKYSINTGAYALVFVTILLVIFFVAWFVYDRGIRRNGGFSRFEEIRLGDDGLIENNRTDRVVNIIVR-LGLCISLITKSAFQRAKAGTAQLSSKFRARFGNKKGATYSSLLHDQLSDEPD----GFHEDSNDLSSFRGQGSNSEIEQEDVDTSQQEHTLRTDLLG----ASNIPDALPARS--ASHESDLAAARSEDK------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53751-1", "uniprot_id": "YN94_YEAST", "id": "P53751-1", "name": "Uncharacterized membrane glycoprotein YNR065C", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLMTGSVGDGSEFDWEDQKTFISRDGGLTWRFVHNSSGLYATGDLGNIIVYIP--YDPEEDGDFQSEFYYSLDQGRTWNEYELTNAISSVHPYKLINPTPDGSGSKFIFKG-TFATTDSETNSITSLKGVEYIIDFSAAFDSRTCEEEDFEDWDLADGKCVNGAKYKYRRRKQDAQCLVKKAFKDLS--LDETPCNSCGESDYECSFEFVRDANGLCIPDYNLIAFSNICD-KSKDKSVLVEPLQLIKGDECKTPMKIEPVDIPCDEIPEEGSSDREIVTTENKFDFEIKFYQYFDTVADESLVMLNSIGDAYISHDGGQTIKRFDTNGEKIVEVVFNPYFN---SSAYLFGSKGNIFSTHDRGHSFMIAKLPEARQLGMPLDFSAKAQDTFIYYGGKNCESILSPECHAVAYLTKDGGETFTEMLDNAIHCEFAGTLFEYPSNEEMVMCQVKKKSSETRSLVSSIDFFQGDNKIIFENIIGYLSTGGYIIVAVPHEDNELRAYVTIDGTEFAEAKFPYGQDVSKQEAFTILGSEKGSIFLHLATNLESGHDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKVQGLEGIIITNIVSNREKVGENKEDEQLKTKITFNDGSDWNFLKPPKKDSEGKKFPCDSVSLDKCSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGDKLLPYEECSTFLTTDGGETWTEVKKGPHQWEYGDHGGVLVLVPENAETDSISYSTDFGKTWKDYKFCGDKVLVKDIITVPRDSALRFLLFGEAKNMGSGSFRTYTIDFRNIFERQCEFDITGKKRADFKYSPLGSRTGCLFGHQTEFLRKTDEKCFIGNIPLSEFSRNVKNCSCTRQDFECDYNFYKASDGTCKLVKGLSSANGADICKKEPDLIEYYDSSGYRKIPLSTCKGGLKLDAHLAPHPCPGKEKAFREKYSINTGAYALVFVTILLVIFFAAWFVYDRGIRRNGGFSRFEEIRLGDDGLIENNRTDRVVNIIVR-LGLCISLITKSAFQRTKAGVARFSSKLRARFGNRKGPTYSSLLQGQFSDESD----GLHEDANDLSSFTSQDSNFEIEQEDAYRPEQEHTSQIDQPA----TSNIPDALPARS--AIHKPDSTAVRNEDE------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P32319-1", "uniprot_id": "VPS10_YEAST", "id": "P32319-1", "name": "Vacuolar protein sorting/targeting protein VPS10", "aln": "MILLHFVYSLWALLLIPLTNAEEFTPKVTKTIAQDSFDILSFDDSNTLIRKQDTSVTISFDDGETWEKVEGIEGEITWIYIDPFNRHDRAVATAMNGSYLYITNDQGKSWERITLPDSGESISPRECYIETHPLNKNYFLAKCNYCEKTEVNNDNEENSGDEEGQFEIFNITRCTDKVFASNDGGKSFSEIKSSLERNENSPISISDCGFAKTSKDSDLESSDTSIICLFQNMQLIMDEFSSPYTESKLVLTTDWGKSLKEFDQFKDKVVNGYRILKSHMVVLTQGDRYNDMSSMDVWVSNDLSNFKMAYMPTQLRHSMQGEIYEDAMGRIILPMSRERSDQEEDKGIVSEILISDSQGLKFSPIPWTANEVFGYINFYQPTYLKGTMIASLYPLSRRRNRKGKAKGVKSKGVTKISVDNGLTWTMLKVVDPDNADSFDCDITDFENCSLQNMFYTREGSTPTAGILMTTGIVGDGSVFDWGDQRTFISRDGGLTWKLAFDFPCLYAVGDYGNVIVAIP--YNADEDDDPQSEFYYSLDQGKTWTEYQL---ETTIYPNEVMNTTPDGSGAKFILNGFTLAHMDGTTN-------FIYAIDFSTAFNDKTCEENDFEDWNLAEGKCVNGVKYKIRRRKQDAQCLVKKVFEDLQ--LFETACDKCTEADYECAFEFVRDATGKCVPDYNLIVLSDVCD-KTKKKTVPVKPLQLVKGDKCKKPMTVKSVDISCEGVPKKGTNDKEIVVTENKFDFKIQFYQYFDTVTDESLLMINSRGEAYISHDGGQTIKRFDSNGETIIEVVFNPYYN---SSAYLFGSKGSIFSTHDRGYSFMTAKLPEARQLGMPLDFNAKAQDTFIYYGGKNCESILSPECHAVAYLTNDGGETFTEMLDNAIHCEFAGSLFKYPSNEDMVMCQVKEKSSQTRSLVSSTDFFQDDKNTVFENIIGYLSTGGYIIVAVPHENNELRAYVTIDGTEFAEAKFPYDEDVGKQEAFTILESEKGSIFLHLATNLVPGRDFGNLLKSNSNGTSFVTLEHAVNRNTFGYVDFEKIQGLEGIILTNIVSNSDKVAENKEDKQLKTKITFNEGSDWNFLKPPKRDSEGKKFSCSSKSLDECSLHLHGYTERKDIRDTYSSGSALGMMFGVGNVGPNLLPYKECSTFFTTDGGETWAEVKKTPHQWEYGDHGGILVLVPENSETDSISYSTDFGKTWKDYKFCADKVLVKDITTVPRDSALRFLLFGEAADIGGSSFRTYTIDFRNIFERQCDFDITGKESADYKYSPLGSKSNCLFGHQTEFLRKTDENCFIGNIPLSEFSRNIKNCSCTRQDFECDYNFYKANDGTCKLVKGLSPANAADVCKKEPDLIEYFESSGYRKIPLSTCEGGLKLDAPSSPHACPGKEKEFKEKYSVSAGPFAFIFISILLIIFFAAWFVYDRGIRRNGGFARFGEIRLGDDGLIENNNTDRVVNNIVK-SGFYVFSNIGSLLQHTKTNIAHAISKIRGRFGNRTGPSYSSLIHDQFLDEADDLLAGHDEDANDLSSFMDQGSNFEIEEDDVPTLEEEHTSYTDQPT----TTDVPDTLPEGNEENIDRPDSTAPSNENQ------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P25657-1", "uniprot_id": "YCY9_YEAST", "id": "P25657-1", "name": "Uncharacterized protein YCR099C", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRSIFLLHFDYKTCEEEDFEDWNLADGKCLNGAKYMYKRRKQDARCLVKRTFKDMI--LHEIPCDSCTESDYECSSEFVRDAKGDCIPDYDQIALSDICD-KANGETVSLEPLQLIKGDKCKKPMEIEAMNIPCEKILRESSNGKKIATIENKFDFEI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q9JLC4-1", "uniprot_id": "SORC1_MOUSE", "id": "Q9JLC4-1", "name": "VPS10 domain-containing receptor SorCS1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGK-VGAGDGSSAGLSALLAGAGLLMLLAPGVCSSLSCCPPQHPSSTPRRTLTPRGFPHPGPLGRAPA----------------------TPPPLFMRPLFAVAP-GDRALFLERAGGSRVSVATAARSGR-----RRRSGTEPEKIE-----------PGEGASRSRRDMLKDGGQ-----QGLGTG-----------------ARDPGKATRFRMEELRLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNK---CKIMLLTDPEIESSLLISSDEGATYQKYRLNFYLQSLLFHPKQEDWILAYSQDQKLYSSAEFGRRWQLIQESVVPNRFYWSVMGSSKEPDLVHLEARTVDGHSIYLTCRMQNCTEANRNKPFPGYIDPDSLIVQDDYVFVQLTSGGRPHYYVSYRRSPFAQMKLPKYALPKDMHVISTDENQVFAAVQEWNQNDTYN--LYISDTRGVYFTLALENVRSSRGPEGNVMIDLYEVAGIKGMFLANKKIDNQVKTFITYNKGRDWRLLQAPDA-------DLRGDPVHCLLPYCSLHLHLKVSENPYTSGIIASRDTAPSIIVASGNIGSELS--------DSDISMFVSSDAGNTWR------QIFEEEHSILYLDQGGVLVAMKHTSLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFG-HFSHRSEWQLVKVDYKSIFDRRCAEEDYRPWQLHSQG--------EACIMGAKRIYKKRKSERKCMQ--KYAGAMESEPCVCTEADFDCDYGYERHSNGQ-------CLPAFWFNPSSLSKDCSLGQSYLNSAGYRKVVSNNCTDGVREQYTAKPQKCPGKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDGI-AVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVLWPS---------------------QVGTLTYVWWYGNNTEPLITLEGSISFKFTSEGMNTITVQVSAGN---AILQDTKTIAVYEEFRSLRLAFSPNLDDYNPDIPEWRRDISRVIKKSLVEATGIPSQHILVAVLPGLPTAAELFVLP-YQDGTRENKRSPEDLEQISEVLIHKLNQNLVHFELKPGVQVLVHAAHLTAAPLVDLTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRRVA----------------LPSPPSPS-AQPGDSSLRLQRPR------------PATPPSSPKRGS---AGAQFAI------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6AEA1-1", "uniprot_id": "A0A8I6AEA1_RAT", "id": "A0A8I6AEA1-1", "name": "VPS10 domain-containing receptor SorCS1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGK-VGAGDGSSAALSALLTGAGLLMLLAPGICSSLSCCPPQHPSSTPRWTLTPRGFSYPGPLGRAPA----------------------TPPPLFMRPLFAVAP-GDRALFLERAGGSRVSVATASRSGR-----RRRSGMDPEKTE-----------PGEGTSRSRRDMLRDGGQ-----QGPGTG-----------------ARDPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNK---RKIMLLTDPEIESSLLISSDEGATYQKYRLNFYIQSLLFHPKQEDWILAYSQDQKLYSSAEFGRRWQLIQEAVVPNRFYWSVLGSNKEPDLVHLEARTVDGHSIYLTCRMQNCTEANRNKPFPGYIDPDSLIVQDDYVFVQLTSGGRPHYYVSYRRNPFAQMKLPKYALPKDMHVISTDENQVFAAVQEWNQNDTYN--LYISDTRGVYFTLALENVQSSRGPEGNVMIDLYEVAGIKGMFLANKKIDNQVKTFITYNKGRDWRLLQAPDA-------DLRGDPVHCLLPYCSLHLHLKVSENPYTSGIIASRDTAPSIIVASGNIGSELS--------DSDISMFVSSDAGNTWR------QIFEEEHSILYLDQGGVLVAMKHTSLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFG-HFSHRSEWQLVKVDYKSIFDRRCAEEDYRPWQLHSQG--------EACIMGAKRIYKKRKSERKCMQG-TYAGAMESEPCVCTEADFDCDYGYERHSSGQ-------CLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDGVREQYTAKPQKCPGKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDGI-AVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVLWPS---------------------QVGTLTYVWWYGNNTEPLITLEGSISFKFTSEGMNTITVQVSAGN---AILQDTKTIAVYEEFRSLRLAFSPNLDDYNPDIPEWRRDISRVIKKSLVEATGIPSQHILVAVLPGLPTAAELFVLP-YQDGARENKRSPEDLEQISEVLIHKLNQNLVHFELKPGVQVLVHAAHLTAAPLVDLTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRKIPGINVYAQMQNEKEQ-ELINPVSHTESRPTAPHPDLRRPGQLVDEKVESHLLDQDKPHHLHRQSGDLLGHNLQSKENPQRLQETC-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8WY21-1", "uniprot_id": "SORC1_HUMAN", "id": "Q8WY21-1", "name": "VPS10 domain-containing receptor SorCS1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGK-VGAGGGSQARLSALLAGAGLLILCAPGVCGGGSCCPSPHPSSAPRSASTPRGFSHQGRPGRAPA----------------------TPLPLVVRPLFSVAP-GDRALSLERARGTGASMAVAARSGR-----RRRSGADQEKAE-----------RGEGASRSPRGVLRDGGQ-----QEPGTR-----------------ERDPDKATRFRMEELRLTSTTFALTGDSAHNQAMVHWSGHNSSVILILTKLYDYNLGSITESSLWRSTDYGTTYEKLNDKVGLKTILSYLYVCPTNK---RKIMLLTDPEIESSLLISSDEGATYQKYRLNFYIQSLLFHPKQEDWILAYSQDQKLYSSAEFGRRWQLIQEGVVPNRFYWSVMGSNKEPDLVHLEARTVDGHSHYLTCRMQNCTEANRNQPFPGYIDPDSLIVQDHYVFVQLTSGGRPHYYVSYRRNAFAQMKLPKYALPKDMHVISTDENQVFAAVQEWNQNDTYN--LYISDTRGVYFTLALENVQSSRGPEGNIMIDLYEVAGIKGMFLANKKIDNQVKTFITYNKGRDWRLLQAPDT-------DLRGDPVHCLLPYCSLHLHLKVSENPYTSGIIASKDTAPSIIVASGNIGSELS--------DTDISMFVSSDAGNTWR------QIFEEEHSVLYLDQGGVLVAMKHTSLPIRHLWLSFDEGRSWSKYSFTSIPLFVDGVLGEPGEETLIMTVFG-HFSHRSEWQLVKVDYKSIFDRRCAEEDYRPWQLHSQG--------EACIMGAKRIYKKRKSERKCMQG-KYAGAMESEPCVCTEADFDCDYGYERHSNGQ-------CLPAFWFNPSSLSKDCSLGQSYLNSTGYRKVVSNNCTDGVREQYTAKPQKCPGKAPRGLRIVTADGKLTAEQGHNVTLMVQLEEGDVQRTLIQVDFGDGI-AVSYVNLSSMEDGIKHVYQNVGIFRVTVQVDNSLGSDSAVLYLHVTCPLEHVHLSLPFVTTKNKEVNATAVLWPS---------------------QVGTLTYVWWYGNNTEPLITLEGSISFRFTSEGMNTITVQVSAGN---AILQDTKTIAVYEEFRSLRLSFSPNLDDYNPDIPEWRRDIGRVIKKSLVEATGVPGQHILVAVLPGLPTTAELFVLP-YQDPAGENKRSTDDLEQISELLIHTLNQNSVHFELKPGVRVLVHAAHLTAAPLVDLTPTHSGSAMLMLLSVVFVGLAVFVIYKFKRRVA----------------LPSPPSPS-TQPGDSSLRLQRAR------------HATPPSTPKRGS---AGAQYAI------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PN08-1", "uniprot_id": "A0A8M9PN08_DANRE", "id": "A0A8M9PN08-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MERGIRYCRVHVRAFCTLLLILFAWVPVAETVITCRSCHLLDKWSGRELLVKMDSGVDS-GKVGDQDG----------------------DGSLFNLAGAETGQPDCGASDSGEHAHSVRKRNTESLRSGKTPPDEKWKSMRSHDKVYNLKLAASRATAPGDPHHRVRRGTQEPGSPPGARFQPLGFGNVTARAARRVPRSELRWNRDERRTAASRQEELKLTSSTFALTGDSAHNQAMVHWSGQNSSVILMLTKLYDFNLGSVTESSLWRSTDYGTTYEKLNEKVGVKTILSYLYVSPNNK---RKIMLLTDPEVESSLLISSDEGATYQKYRLNFYILSLLFHPEQEDWILAYSHEQKLYSSVEFGRRWQLVHERVAPNRFYWSKTGLDKEPGLIHLETSISESQALYVTCKLQNCTDANKGKPFPGYIDPNSLVVQDEYVFVQVSTGGRPIYYVSSRRDVFTPMKLPKYTLPKDLHVISTDENRVVAAVQEWNQNDTYN--LYVSESGGIYYTLALENVMSSMGPEGNVMIDLYEVAGIKGMFLANKKLNNEVKTYITYNKGRDWRLLQAPSA-------DLRGNRIHCMLPYCSLHLHLHVSANPYTSGNIASRESAPGIILASGSIGAELT--------SSNVSMFITSDAGNTWR------QIFDEEYSVLYLDQGGALVAIRHTPLPIRHLWLSFDEGRVWNKYSFTSSPLFVDGVLGEPGEETLIMTIFG-HVSHRSEWQLVKIDFRSIFNRRCVESDYVPWDLHDQG--------ERCLMGVKRVYRKLKATARCVMGKTYSVTMISEPCHCTESDFECDYGFERRTDGK-------CTPAFWFPPSSMSRTCTTEHTFLNSTGYRKVVSNNCTGGVIERYTARRQLCPSQAPRGLHLVTSEGKLTATLASNVTFLVFLEEGDGSKTSITVDFGDGN-AFTYSNVSSIEDGIKHIYKTVGIYRVSATAENSLGSETVLLFLHVTCQLDSIHLSAPFVAVKNKEVNLTVVLYPS---------------------QVGTVTYIWWFGNNSEPVITLDGSVSFTFSREGISIVTVQVSAGN---NILQDRKTIAVHEYFRSHLLAFSSNLDDHNPDVAEWRLDVSRVIKTSMMQATGVSPDLLLVTVLPGLPTAAEFFLLPDKQLTEGKPDKTATHLDQLSEVVLSALNQNLVQFTLRPGVQITVYAAHLSAAPLVDTSENHSGSAMLMLLSVVVLGLAIFLIYKFKRKIPGLHVYAAMQDEKEQEMIQSPVSPTDSTPSSSSQRELLTS------------LEPLDTEPNTQTIECIKPHPRVKFSSDLPTYIDV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :: *: : * ...:: : : . :: : . * : :: * :.. * .: :*: .*.. : . :. : . . :: . ", "identical_positions": 8, "similar_positions": 39, "identity": "0.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101223-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H0F6-1", "uniprot_id": "SHRPN_HUMAN", "id": "Q9H0F6-1", "name": "Sharpin", "aln": "MAPPAGGAAAAASDLGSAAVLLAVHAAVRPLGAGPDAEAQLRRLQLSADPERPGRFRLELLGAGPG--AVNL-EWPLESVSYTIRGPTQHELQPPPGGPGTLSLHFLNPQEAQRWAVLVRGATVEGQNGSKSNSPPALGPEACPVSLPSPPEASTLKGPPPEADLPRSPGNLTEREELAGSLARAIAGGDEKGAAQVAAVLAQHRVALSVQLQEACFPPGPIRLQVTLEDAASAASAASSAHVALQVHPHCTVAALQEQVFSELGFPPAVQRWVIGRCLCVPERSLASYGVRQDGDPAFLYLLSA-------------------PREAPATGPSPQHPQKMDGELGRLFPPSLGLPPG------------------PQPAASSLPSP-LQPSWSCPSCTFINAPDRPGCEMCSTQRPCT--WDPLAAAST-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91WA6-1", "uniprot_id": "SHRPN_MOUSE", "id": "Q91WA6-1", "name": "Sharpin", "aln": "MSPPAGGAAVAA-DPASPVVLLAVHAAVRPLGAGQDAEAQPRKLQLIADPERPGRFRLGLLGTEPG--AVSL-EWPLEAICYTVRGPNQHELQPPPGGPGTFSVHFLDPEEAQQWAALVRDATAEGQNGSGS-PAPAPAPAMCPISPPCSSMAQIPKATQPEVDLPQSSGNFK-KEELATRLSQAIAGGDEKAAAQVAAVLAQHHVALNVQLMEAWFPPGPIRLQVTVEDATSVLSSSSSAHVSLKIHPHCSIAALQDQVFSEFGFPPAVQRWVIGRCLCMPERSLASYGVSQDGDPAFLYLLSA-------------------PREV--SGQSLQN-SKMDRKLG-LFPQSLGLPHD------------------LQPSSSSLPSP-SQPGWSCPSCTFINASNRPGCEMCSTQRPCA--WDPLAAAST-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "X1WDE8-1", "uniprot_id": "X1WDE8_DANRE", "id": "X1WDE8-1", "name": "", "aln": "MSTSTG----------CSTVLMSVRVSVRPLPVGSDS----LRLQLSMNPNRAGLFTLTLRHTDRGGRSVSLAEFDLRSVQYELKSPRCHELRLLKPPHDCLSFSFRSEQEAQEWATVVMSSLRESHR----------------VASICQEGLQYVKSGEKSAVLS-----LSMKEELCVELSRAIEAGDAQAAARYATDLAQQQMTLSIQPAPRDTDDKDISLAVIVEDAS------SSCCVTVKIHPHVTVASLKQQMFVEYGFHPRVQRWIISQCLCSDSRSVSSYGVCRDGDTAFLYLLSAGHASLSQQQENGLSVPTAAPANASLSAPAGGGSSGHDWRAYSTLPPRFSHASTGSGGSEKPSVTDIINLEMLQLGGSKLKSSNTQSGWPCPSCTFINKSTRPGCEICSTDRPNPPHHTHLQQEKSRRSNQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:..:* ...**::*:.:**** .* *: :*** :*:*.* * * * : * :*.* *: *.:: * ::.* ***: . :*. * . :***.**.:* .: *.:. :: . . *. .. *. :. :***. *::** .** :.**: *: ***::::*.:* * * * :***: **. *::::*** ::*:*::*:* * ** * ****:*.:*** .**::**** :***.******** * :. :. : . * . :* :. . * ..*.* *. *..*.******** . *****:***:** . * .: ", "identical_positions": 130, "similar_positions": 112, "identity": "29.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101223-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADJ8-1", "uniprot_id": "D4ADJ8_RAT", "id": "D4ADJ8-1", "name": "", "aln": "MEGLVLLKALVTRLLFLLHSLVAVWRVTWVKEEHRYWLLALLNLLLVLETVLTLKFKRGRGYKWLSPAIFLYLINIMPSLWLLEMHHGNQYCSTQSETAAQNFSGRGDINQTLSSHRATDGVGNILELARGFVDNLSMVCEPVWTLGLHQTLLLILIIGRWLLPIGGTITRDQLSELLLMFVGTAADILEFTTETLKENNVRNNPALVSGILVVWTWSMLQFPLDLAVQLKLVCPASVKARG--FLRVFLCQYSADLWAIGLSFFIQDGPFLVVRLVLMIYFKVINHMLVFFAVKNSLVMALHFYRLVALIMATRDFMQDHPESPKTEHSGPDQPSESGPS--EWEDTSPE--ALPLRISPVTSEESYPTTP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UP23-1", "uniprot_id": "TMM26_MOUSE", "id": "Q3UP23-1", "name": "Transmembrane protein 26", "aln": "MEGLVLLKALVTRLLFLLHSLVAVWRVTWVKEEHRYWLLALLNLLLVLETVLTLKFKRGRGYKWLSPAIFVYLVNIMPSLWLLEMHHGNQYCSTQSERMAQNFSRRGDVNQTLSSHRATNGMGNILELARGFVDNLSMVCEPVWTLGLHQTLLLILIIGRWLLPIGGTITRDQLSELLLMFVGTAADILEFTTETLKENNVRTNPTLVSGILVVWTWSMLQFPLDLAVQLKLVCPASVKARG--FLRVFLCQYSADLWAIGLSFFIQDGPFLVVRLVLMIYFKVINHMLVFFAVKNSLVMALHFYRLVALIMATRDFMRDHPESPKPEHSGPDQPSESGPS--EWEDASPE--ALPLRTSPVTSEESYPTTP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZUK4-1", "uniprot_id": "TMM26_HUMAN", "id": "Q6ZUK4-1", "name": "Transmembrane protein 26", "aln": "MEGLVFLNALATRLLFLLHSLVGVWRVTEVKKEPRYWLLALLNLLLFLETALTLKFKRGRGYKWFSPAIFLYLISIVPSLWLLELHHETQYCSIQAEGTSQNTSRKEDFNQTLTSNEQTSRADDLIETAKVFVNNLSTVCEKVWTLGLHQTFLLMLIIGRWLLPIGGGITRDQLSQLLLMFVGTAADILEFTSETLEEQNVRNSPALVYAILVIWTWSMLQFPLDLAVQN-VVCPVSVTERG--FPSLFFCQYSADLWNIGISVFIQDGPFLVVRLILMTYFKVINQMLVFFAAKNFLVVVLQLYRLVVLALAVRASLRSQSEGLKGEHGCRAQTSESGPSQRDWQNESKEGLAIPLRGSPVTSDDSHHTP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q715-1", "uniprot_id": "A0A8M1Q715_DANRE", "id": "A0A8M1Q715-1", "name": "", "aln": "MILVKFVCAIITRSLFILVSLIGVWRVKTVKNDNMYWLLTILYLPLVVEMIITLKRRKGQDYKWFSPAILLFLISIIPSIWILELHHQENKAS---DPQCRKLDSWDNVKSILPSNGTMG-----NATLKYLESMLTSVCANDWILALHQVLLILLILGKWLLPLGGGVTRDELSQLLLIFVGTAADILEFTSETLSDVKE-NNHQLVYIILAVWTWSMLQFPLHLAVVTSRPENTDEPKGGDGCCNLILSRHSTDIWNIVESLFIQDGPFLVVRLIVMIYFDVFHQMLVFFAIKNFLVVVLNLYRLIVICQDFR----------------PKPPSSSSS--------------VPI---------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : :: *: ** **:* **:.****. **:: ****::* * *.:* :*** ::*:.***:****:::*:.*:**:*:**:** : .* : .:: . :.:. *.*: . : : . *: ** * *.***.:*::**:*:****:** :***:**:***:************:***.: : .. ** **.:**********.*** .. * :::.::*:*:* * *.************::* **.*:::****** ** **:.*::***:.: * .*.*.. :*: ", "identical_positions": 144, "similar_positions": 98, "identity": "38.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101223-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H694-1", "uniprot_id": "BICC1_HUMAN", "id": "Q9H694-1", "name": "Protein bicaudal C homolog 1", "aln": "--------------------------MAAQGEPGYLAAQ-SDPGSNSE--------RSTDSPVPGSEDDLVAGA-TLHSP---EWSEERFRVDRKKLEAMLQAAAEGKGRSGED-FFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEETGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESARVRIRELLPLVLMFELPIAGILQPVPDPNSPSIQHISQTYNISVSFKQRSRMYGATVIVRGSQNNTSAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNIKHIMQRTGAQIHFPDPS----NPQKKSTVYLQGTIESVCLARQYLMGCLPLVLMFDMKEEIEVDPQFIAQLMEQLDVFISIKPKPKQPSKSVIVKSVERNALNMYEARKCLLGLESSGVTIATSPS-----PASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSTTPN------------SLLNALNSSVSPLQSPSSGTPSPTLWAPPLANTSSATGFSAIPHLMIPSTAQATLTNILLSGVPTYGHT-APSPPPGLTPVDVHINSMQTEGKKISAALNGHAQSPDIKYGAISTSSLGEKVLSANHGDPSIQTSGSEQTSPKSSPTEGCNDAFVEVGMPRSPSHSGNAGDLKQMMCPSKVSCAKRQTVELLQGTKNSHLHSTDRLLSDPELSATESPLADKKAPGSERAAERAAAAQQ------------NSERAHLAPRSSYVN-MQAFDYEQKKLLATKAMLKKPVVTEVRTPTNTWSGLGFSKSMPAETIKELRRANHVSYKPTMTTTYEGSSMSLSRSNSREHLGGGSESDNWRDRN------GIGPGSHSEFAASIGSPKRKQNKSTEHYLSSSNYMDCISSLTGSNGCNLNSSFKGSDLPELFSKLGLGKYTDVFQQQEIDLQTFLTLTDQDLKELGITTFGARRKMLLAISELNKNRRKLFESPNAR-TSFLEGGASGRLPRQYHSDIASVSGRW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99MQ1-1", "uniprot_id": "BICC1_MOUSE", "id": "Q99MQ1-1", "name": "Protein bicaudal C homolog 1", "aln": "--------------------------MASQSEPGYLAAAQSDPGSNSE--------RSTDSPVAGSEDDLVAAAPLLHSP---EWSEERFRVDRKKLEAMLQAAAEGKGRSGED-FFQKIMEETNTQIAWPSKLKIGAKSKKDPHIKVSGKKEDVKEAKEMIMSVLDTKSNRVTLKMDVSHTEHSHVIGKGGNNIKKVMEDTGCHIHFPDSNRNNQAEKSNQVSIAGQPAGVESARARIRELLPLVLMFELPIAGILQPVPDPNTPSIQHISQTYSVSVSFKQRSRMYGATVTVRGSQNNTNAVKEGTAMLLEHLAGSLASAIPVSTQLDIAAQHHLFMMGRNGSNVKHIMQRTGAQIHFPDPS----NPQKKSTVYLQGTIESVCLARQYLMGCLPLVLMFDMKEDIEVDPQVIAQLMEQLDVFISIKPKPKQPSKSVIVKSVERNALNMYEARKCLLGLESSGVSIATSLS-----PASCPAGLACPSLDILASAGLGLTGLGLLGPTTLSLNTSATPN------------SLLNALNTSVSPLQSSSSGTPSPTLWAPPIANTASATGFSTIPHLMLPSTAQATLTNILLSGVPTYGHT-APSPPPGLTPVDVHINSMQTEGKNISASINGHVQPANMKYGPLSTSSLGEKVLSSNHGDPSMQTAGPEQASPKSNSVEGCNDAFVEVGMPRSPSHSGNAGDLKQMLGASKVSCAKRQTVELLQGTKNSHLHGTDRLLSDPELSATESPLADKKAPGSERAAERAAAAQQ------------KSERARLASQPTYVH-MQAFDYEQKKLLATKAMLKKPVVTEVRTPTNTWSGLGFSKSMPAETIKELRRANHVSYKPTMTTAYEGSSLSLSRSSSREHLASGSESDNWRDRN------GIGPMGHSEFSAPIGSPKRKQNKSREHYLSSSNYMDCISSLTGSNGCNLNSCFKGSDLPELFSKLGLGKYTDVFQQQEIDLQTFLTLTDQDLKELGITTFGARRKMLLAISELSKNRRKLFEPPNASCTSFLEGGASGRLPRQYHSDIASVSGRW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58HRB2-1", "uniprot_id": "A0AC58HRB2_DANRE", "id": "A0AC58HRB2-1", "name": "", "aln": "-----------------------------MAEP--LSFMHHDHGSSSE--------RSDDSPSAVSEDDSSGHCGHISPPDP-DWTEERFRVDRKKLETMLLAANEGR-INGDD-FFQKVMDETNTQIAWPSKLKIGAKSKKDPHIKVSGKRDDVREAKEKIMSVLDTKSHRVTLKMDVSHTEHSHVIGKGGHNIKRVMEETGCHIHFPDSNRHSQAEKSNQVSIAGQLTGVEAARVKIRELLPLVLMFEC--SGVVQLV-DCSSPVVQHISHTYNVSISFRPPSRLYGNTAIVRANQNNSSGVKRGTALLLEHLAGSLASSVLVSTQLDIAPQHHHFLLGRNGANIKLISQRTGAHIHFPEISPH-NSNASRSAVYIQGSIDAVCAARQQIMGCLPLVLLFDIKEETEVASQVITTLMEQLDVFISIKPKPKQPSKSVIVKSVERNAGSLYEVRRILLGLESSCLSSSVSSVSVNGHISSSPPRIASIGLDTLASAGLRLSTLAGLLRSSVSPVPNGSPNPSCALNGHGSVLNIQNGVNNTQHIHTPAHTHSHTPSLWASALSSAADAAGFS--TDLMLQSVSQATLGGLLLSGVQSQAHAHTPSPPPGLAPIHKTVS---------AEHLNGHLASS--VYSRISSVSL-----NSAHCDMAQEGIGHTQSEAKS--TDEGSDTFVEVGMPRSPSHSANGSELKQMLASCTVSPGKRQTVELLQRTKNTLLH-VECVLAD----SDDNPMTDKRAPGSERAAERRLAPHMQVYMLMCKHCTHNSAQTKSHSQCLCVNIFQAFDYEKKKLLATKAMLKKPVVTEIRTPTNTWSGLGFSKSMPAESIKELRRAHHVPYKPSMGTTYEDSHLSMSHSGIQEGLINDTKSDNWGDLNGNVNINGNGPSGNSEFSQTVSSTKRIKNKSREQYLSSSNYMDSIS-LTGSNGISLSSSLKGTDLPELFSKLGLGKYTDIFQQQEIDLQTFITLTDPDLKELGITTFGARRKMLLAISELNKSRRKLFDTANIR-SSFLEGGASGRLTRHFHSDMASVSGRW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24009-1", "uniprot_id": "BICC_DROME", "id": "Q24009-1", "name": "Protein bicaudal C", "aln": "MLSCASFNKLMYPSAADVAKPPMVGLEVEAGSIGSLSSLHALPSTTSVGSGAPSETQSEISSVDSDWSDIRAIAMKLGVQNPDDLHTERFKVDRQKLEQLIKAESSIEGMNGAEYFFHDIMNTTDTYVSWPCRLKIGAKSKKDPHVRIVGKVDQVQRAKERILSSLDSRGTRVIMKMDVSYTDHSYIIGRGGNNIKRIMDDTHTHIHFPDSNRSNPTEKSNQVSLCGSLEGVERARALVRLSTPLLISFEMPVMGPNKPQPDHETPYIKMIETKFNVQVIFSTRPKLHTSLVLVKGSEKESAQVRDATQLLINFACESIASQILVNVQMEISPQHHEIVKGKNNVNLLSIMERTQTKIIFPDLSDMNVKPLKKSQVTISGRIDDVYLARQQLLGNLPVALIFDFPDNHNDASEIMS-LNTKYGVYITLRQKQRQSTLAIVVKGVEKFIDKIYEARQEILRLATPFVKPEIPDY-------------------YFMPKDKDLNLAYRTQLTALLAGYVDSPK-------------TPSLLPPSLAGQLTPYANNNHLLLNANGLATPTGVCAPTQKYMQLHNSFQQAQNRSMVAGGQSNNGNYLQVPGAVAPPLKPPTVS---------------------------------------PRNSCSQNTSGYQSFSSSTTSLEQSYPPYAQLPGTVSSTSSSTAGSQNRAHYSPDSTYGSEGGGVGGGGGGGARLG---RRLSDGVLLGLSNSNGGGGNSGGAHLLPGSAESYR---------------SLHYDLGGNKHSGHRAFDFDMKRALGYKAMERTPVAGELRTPTTAWMGMGLSSTSPAPAPLENG---------------------------ENGAAGGGASSGWRLPP--------GLGSPYGLSATTGLLDATPVNRR------------------------MQLAKHKDIQTLLTSLGLEHYIKIFVLNEIDLEVFTTLTEENLMELGIAAFGARKKLLTAIHTLLANEAACSTMPSSS--SSQNSSSPRFSGSAAPGAERRPSNQW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. *: .:.* :* *. . .* . . : : ***:***:*** :: * . . .* : **:.:*: *:* ::**.:************::: ** ::*:.*** *:* **::. ** :*****:*:**::**:**:***::*::* ********* . :*******:.*. *** **. :* **:: ** * : * .:* :: *. .:.:.: * .::: . *:..:::: *: .* :*::. . *:** : *..*::*:.*** :: *:*. *: * :** ::* **: * . .:* * :.* *: * *** ::* **:.*:**: :: : .:.:: * : .*:*::: * :*.: :::**.**: .:**.*: :* * :. :. . : . . *. ::: :*: . : : .. : . * * ::..:.. . : : * ** .:: .* . .: . . . . :. : . : : * . ...: : .:.:: . *.: *..... :: . : ... .: * *:* . ... . .*. : . : :***:: *: *. *** :.**. *:****.:* *:*:*.: ** : * .: .. *..* * . :: . . . : . * .*: *::.*** :* .:* :****:.* ***: :* ****::****:*:* ** * .. .. * :..:. . *.:*", "identical_positions": 220, "similar_positions": 295, "identity": "20.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101229-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62923-1", "uniprot_id": "PNOC_RAT", "id": "Q62923-1", "name": "Prepronociceptin", "aln": "MKILFCDVLLLSLLSSVFSSCPEDCLTCQERLHPAPGSFNLKLCILQCEEKVFPRPLWTLCTKAMAS----------DSEQLSPADPELTSAALYQSKASEMQHLKRMPRVRSVVQARDAEPEADAEP------VADEADEVEQ-------------------------------------KQLQKRFGGFTGARKSARKLANQKRFSEFMRQYLVLSMQSSQR---RRTLHQNGNV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64387-1", "uniprot_id": "PNOC_MOUSE", "id": "Q64387-1", "name": "Prepronociceptin", "aln": "MKILFCDVLLLSLLSSVFSSCPRDCLTCQEKLHPAPDSFNLKTCILQCEEKVFPRPLWTVCTKVMAS----------GSGQLSPADPELVSAALYQPKASEMQHLKRMPRVRSLVQVRDAEPGADAEPGADAEPGADDAEEVEQ-------------------------------------KQLQKRFGGFTGARKSARKLANQKRFSEFMRQYLVLSMQSSQR---RRTLHQNGNV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13519-1", "uniprot_id": "PNOC_HUMAN", "id": "Q13519-1", "name": "Prepronociceptin", "aln": "MKVLLCDLLLLSLFSSVFSSCQRDCLTCQEKLHPALDSFDLEVCILECEEKVFPSPLWTPCTKVMAR----------SSWQLSPAAPEHVAAALYQPRASEMQHLRRMPRVRSLFQEQE-EP----EP------GMEEAGEMEQ-------------------------------------KQLQKRFGGFTGARKSARKLANQKRFSEFMRQYLVLSMQSSQR---RRTLHQNGNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RJ67-1", "uniprot_id": "A0A8M1RJ67_DANRE", "id": "A0A8M1RJ67-1", "name": "", "aln": "MKAPLWTLLLLGLCNPAWCDCQKDCLFCSQKLP-NEYAFNNLVCLVECHGKLSPGDTWEMCRRTIVEQKPKALLSVEGSILKRAEEEPDTSLPVDQDDEQLSETLQRFDHITRALGADDQDRQLSKKYKFLQVQSAQESEEERDGDSEIEGDEQESAIHLIKRFGGFLKNKYGYRKFIDPGRSLQKRYGGFIGVRKSARKWNNQKRFSEFLKQYLGMSSRASEYNSMSADLTQQNE-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : :***.* ...:..* .*** *.::* :*: *:::*. *: * * * :.:. .* . .: .: * . : *:*: :: . : : : ::: * .: :.****:*** *.****** ********::*** :* ::*: * *:.: ", "identical_positions": 53, "similar_positions": 58, "identity": "22.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101230-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UMS6-1", "uniprot_id": "SYNP2_HUMAN", "id": "Q9UMS6-1", "name": "Synaptopodin-2", "aln": "MGTGDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPEVIKLMESITDSLQMLIKRPSSGISEALISENENKNLEHLTHGGYVESTTLQIRPATKTQCTEFFLAPVKTEVPLAENQRSGPDCAGSLKEETGPSYQRAPQMPDSQRGRVAEELILREKVEAVQPGPVVELQLSLSQERHKGASGPLVALPGAEKSKSPDPDPNLSHDRIVHINSIPTNEKADPFLRSSKIIQISSGRELRVIQESEAGDAGLPRVEVILDCSDRQKTEGCRLQAGKECVDSPVEGGQSEAPPSLVSFAVSSEGTEQGEDPRSEKDHSRPHKHRARHARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELEREADEEEE---GDKEDTCEVAFLGASESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKKLNRGDKMEMLPDTTGKGALMFAKRRERMDQITAQKEEDKVGGTPSREQDAAQTDGLR--TTTSYQRKEEESVRTQSSVSKSYIEVSHGLGHVPQQNGFSGTSETANIQRMVPMNRTAKPFPGSVNQPATPFSPTRNMTSPIADFPAPPPYSAVTPPPDAFSRGVSSPIAGPAQPPPWPQPAPWSQPAFYDSSERIASRDERISVPAKRTGILQEAKRRSTTKPMFTFKEPKVSPNPELLSLLQNSEGKRGTGAGGDSGPEEDYLSLGAEACNFMQSSSAKQKTPPPVAPKPAVKS-SSSQPVTPVSPVWSPGVAPTQPPAFPTSNPSKG---TVVSSIKIAQPSYPPARP-ASTLNVAGPFKGPQAAVASQNYTP-------KPTVSTPTVNAVQPGAVGPSNELPGMSGRGAQLFAKRQSRMEKYVVDSDTVQAHAARAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAALKSQPSAAQPSKMGKKKGKKP------LNALDVMKHQPYQLNASLFTFQPP------------------------DAKDGLPQKSSVKVNSALAMKQALPPRPVNAASPTNVQASSVYSVPAYTSPPSFFA-EASSPVSASPVPVGIPTSPKQESASSSYFVAPRPKFSAKKSGVTIQVWKPSVVEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91YE8-1", "uniprot_id": "SYNP2_MOUSE", "id": "Q91YE8-1", "name": "Synaptopodin-2", "aln": "MGTGDFICISMTGGAPWGFRLQGGKEEQQPLQVAKIRSQSKASGSGLREGDEVVSINGNPCADLTYPEVIKLMEGITDSLHLLVKRPSSGTSETLDSESETTNHQHLTHEGPMESTTLQIQQATETQSEDFFLAPVQTKVPLTEDQSNAWGYAECPKEEQ------APPMLGSQEGHLVEEVILRQKAEAGQPGHVVELQLSLSKERHQCTSGPIVTLQGNDKSTSPDPDWSSQLERTVHINSIPAPEKADTSLTSS----TSSGRELRVIQGRDPGGAGLPQVEVILDCSDRLKAEECRLQTGRGCVASPVEGGRSEAPPSLVSFAVSSEGTEHGEDQRSGKDQSRPHKHRARHARLRRSESLSEKQVKEAKSKCKSIALLLTDAPNPNSKGVLMFKKRRRRARKYTLVSYGTGELEREEEEEEDQEAGDKDEISEVAFLGTSESEVDEELLSDVDDNTQVVNFDWDSGLVDIEKRLNRGDKMEMLPDTTGKGALMFAKRRERMEQFTAQNEEEKTGGMAGGGPDALQTDGLR--TMTSYQRKEE-SVRMQSSVSESSFQMGRSLASVPQQNGFSGVSETAGAQRMFPMNRTAKPFLGSMNQPAAPFSPTRSVTSPISDFPAPPPYSAVSPPPEAFSRGVSSPVAGPAQPPPWPQPAPWSQPAFYDSSEQIASRDERIAVPAKRTGILQEAKRRGTTKPMFTFKETKVSPNPELLSLLQNAEGKRGT--GGDSGPEEDYLSLGAEACNFMQSS-AKQKTPPPVAPKPAVKSPSSSQPVAPVSPVWSPGVAPAQRPAFSTSNPPNPPQVTAVSSIKIAQPAAPPARP-ASALNLAGPFKGPQAVVVSHNYTP-------KPSAPTPLVNAAPAGAGGPSNELPGMSGKGAQLFAKRQSRMEKYVVDSDTVQAHTVRAQSPTPSLPASWKYSSNVRAPPPVAYNPIHSPSYPLAAIKSQPPGAQASKTSKKKGKKP------LNTLDVMKHQPYQLNASLFTFQPP------------------------DSKDGLPQKSTVKVSSAPAMKQALPPRQANVGSPTNAQASSVYSVPAYTSQPNFFAAEATSPVSASPVPVSVPTSPKQESTSTSYFVAPRPKFSAKKSGVTVQVWKPSVVEE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9QFY4-1", "uniprot_id": "E9QFY4_DANRE", "id": "E9QFY4-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEHLPQTKGKGVLMFAKRRQRMDEISAEHEEMRRKGIPVDAIEETKREIVMPPPQESKQSPQDFYARQEKHYQGQPFQLQMLQQSANSMNGLDPHQGSAVPKPLVSN-RTAKPFFSGHNQGQKTFSPVRGVSSPTSKKPE--------------------------NIFKVPIPVNTTPNVWSPTSDVIASRDERIAIPAIKTGILPETKRRGANKTDLKER--------------PLHQKKRDEKSLTEFVQEEDLLSLGAEACNFMQAPTVKQKNPPPVLPKPVINPAHPLWSADGHAVSTSLLMTSSSAQAMGHNQVQAGHTKQHPAAAWTPEPHQTPHKLRAGPSKSKTPWIKSQSEENSVASCPPQHLSTYLPASKAPSASHQEYSSETGASEGLNLKGKGAELFARRQTRMEKFIVDNETVRTNKVRPSSPTLSMPSTWKYSSNIRAPPPVSYNPILSPFYPLAAVKQPPPATSPKTKPKVNKEKKNPPPKHLNVLDVMKHQPYQLDSSLFTYNFTPEVEEAVSPKDSKPTSANSSSKISQTDKQNPSKATGEVSAVYPFVRQTTSNETAAVAPQQLDGKQLNMYDGTRNKGIFSVRLPPGSSGGNVSVGSSALENNQYASRSVLPVAPRPKFSAKKSNMTGKQWKPMILQH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** **:*.***.*******:**::::*::** : * . : : : : . * * :: .* :. . . ::: . . **:. . :* : :.. ****** .. ** .***.*.::** :. * : * *. : .: :*: ********::** :**** *:***.:.*. :. : : **. : *** ************:. .***.**** ***.::. . .. : * ::.:. *: .: :: .:* .* : *.. : *: .*: * * *: :* .. .: :.* .:.*:**:***:**:****::**.:**::: .*..*** *:*::******:******:**** ** *****:*. *..:.... * : :* **.***********::****:: . ::.. *.*:: :*.:. .: : ... . . :* : :...: . . * . .... ... . . . :* :: : ************.:* : *** :::.", "identical_positions": 191, "similar_positions": 196, "identity": "16.74%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-101230-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2M3X8-1", "uniprot_id": "PHAR1_MOUSE", "id": "Q2M3X8-1", "name": "Phosphatase and actin regulator 1", "aln": "-------------------------------------------------MDYP---KMDYFLDVESAHRLLDVESAQRFFYSQGAQARRATLLLPPTLMAASSEDD-IDRRPIRRVRSKS--------------------------------------------------------------DTPYLAEARISFNLG------------------AAEEVERLAAMRSDSLVPGTHTPPIRRRSKFANLGRIFKPWKWRKKKSEKFKHTSAALERKISMRQSREELIKRGVLKEIYDKDGELS----------------ISNEDDSLENGQS-------LSSSQLSLPALS----------------------EMEPVPMPRDPCSYEVLQASDIMDGPDPGAPVKLPCLP-------------------------------------------VKLSPPLPPKKVLICMPVGGPELTLASYAA-QKSSQQAVAQHHHTVLPSQMQHQLQYGSHGQHLPSSTGTLPMHPSGCRMIDELNKTLAMTMQRLESSEQRVPCSTSYHSSGLHSSDGITKAGPMG-----------------------LPEIRQVPTVVIECDDNKENVPHEPDYEDSPCLYGREEEEEEEDEDDDASLYTSSLAMKVCR---KDSLAIKLSNRPSKRELEEKNILPRQTDEER----LELRQQIGTKLTRRLSQ--------------RPTAEELEQRNILKPRNEQEEQEEKREIKRRLTRKLSQRPTVEELRERK---------------------------------------------ILIRFSDYVEVADAQ---DYDRRADKP-WTRLTAADKAAIRKELNEFKSTEMEVHELSRHLTRFHRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P62024-1", "uniprot_id": "PHAR1_RAT", "id": "P62024-1", "name": "Phosphatase and actin regulator 1", "aln": "-------------------------------------------------MDYP---KMDYFLDVESAHRLLDVESAQRFFYSQGAQARRATLLLPPTLMAASSEDD-IDRRPIRRVRSKS--------------------------------------------------------------DTPYLAEARISFNLG------------------AAEEVERLAAMRSDSLVPGTHTPPIRRRSKFANLGRIFKPWKWRKKKSEKFKHTSAALERKISMRQSREELIKRGVLKEIYDKDGELS----------------ISNEDDSLTNGQS-------LSSSQLSLPALS----------------------EMEPVPMPRDPCSYEVLQASDIMDGPDPGAPVKLPCLP-------------------------------------------VKLSPPLPPKKVLICMPVGGPELSLASYAA-QKSSQQAVAQHHHTVLPSQMQHQLQYGSHGQHLPSSTGTLPMHPSGCRMIDELNKTLAMTMQRLESSEQRVPCSTSYHSSGLHSSDGVTKAGPLG-----------------------LPEIRQVPTVVIECDDNKENVPHEPDYEDSSCLYAREEEEEEEDEDDDASLYTSSLAMKVCR---KDSLAIKLSNRPSKRELEEKNILPRQTDEER----LELRQQIGTKLTRRLSQ--------------RPTAEELEQRNILKPRNEQEEQEEKREIKRRLTRKLSQRPTVEELRERK---------------------------------------------ILIRFSDYVEVADAQ---DYDRRADKP-WTRLTAADKAAIRKELNEFKSTEMEVHELSRHLTRFHRP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9C0D0-1", "uniprot_id": "PHAR1_HUMAN", "id": "Q9C0D0-1", "name": "Phosphatase and actin regulator 1", "aln": "-------------------------------------------------MDYP---KMDYFLDVESAHRLLDVESAQRFFYSQGAQARRATLLLPPTLMAASSEDD-IDRRPIRRVRSKS--------------------------------------------------------------DTPYLAEARISFNLG------------------AAEEVERLAAMRSDSLVPGTHTPPIRRRSKFANLGRIFKPWKWRKKKSEKFKHTSAALERKISMRQSREELIKRGVLKEIYDKDGELS----------------ISNEEDSLENGQS-------LSSSQLSLPALS----------------------EMEPVPMPRDPCSYEVLQPSDIMDGPDPGAPVKLPCLP-------------------------------------------VKLSPPLPPKKVMICMPVGGPDLSLVSYTA-QKSGQQGVAQHHHTVLPSQIQHQLQYGSHGQHLPSTTGSLPMHPSGCRMIDELNKTLAMTMQRLESSEQRVPCSTSYHSSGLHSGDGVTKAGPMG-----------------------LPEIRQVPTVVIECDDNKENVPHESDYEDSSCLYTREEEEEEEDEDDDSSLYTSSLAMKVCR---KDSLAIKLSNRPSKRELEEKNILPRQTDEER----LELRQQIGTKLTRRLSQ--------------RPTAEELEQRNILKPRNEQEEQEEKREIKRRLTRKLSQRPTVEELRERK---------------------------------------------ILIRFSDYVEVADAQ---DYDRRADKP-WTRLTAADKAAIRKELNEFKSTEMEVHELSRHLTRFHRP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58I1V4-1", "uniprot_id": "A0AC58I1V4_DANRE", "id": "A0AC58I1V4-1", "name": "Phosphatase and actin regulator", "aln": "------------------------------------------MHALIRSISAPSRGVTDRHGSAAAAPMAGPAFTGAHGTWITPRLTLREDASSSSSLSSSSSAEKPRKRRAFNLVKLRQP-------------------------------------------------------TAPGNNNTPFVISGHIKHICSNCSR---------GNDIRDAEGAERLAAMRSDSLVPGTHTPPIRRRSKLASLGRLFKPWKWRKKKSDKFKQTSAVLERKMSMRQSREELIKRGVLKEVYEKADEVSGDSARVCVSDLERQTVLSPVSESAESSVTATVSFSEVQSSAEGLPCLS----------------------DLVPKPSQAPPPVKPLQSDSADISHVRPPSLKQPPALPPKPYSRIPNH----------------------------LTETLARLSPPLPPKKVMICEPP--ATFPLKCLPS-QGS------HVHTHTLTHTHSHSQQY---------ATLPLSLHPP-SRIIEELNKTLALTMQRLESSVLQAVPSVLMETE----EEKENRESLHQ-----------------------TPAVTHTHTLVTHT------------------FSTREEEDEEEEEDDDESLFTSTLALRILR---KDSLAIKLSNRPSKRELEDKNILPMMSDQER----LESRQQIGTKLTRRLSQ--------------RPSAEELEQRNILKPRNEQEELEEKRELKKRLSRKLSQRPTVEELREAK---------------------------------------------ILIRFSDYVEVAEAQ---DYDRRADKP-WTRLTAADKAAIRKELNEFKSSEMEVHESSRHLTRFHRP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P53858-1", "uniprot_id": "BNI4_YEAST", "id": "P53858-1", "name": "Protein BNI4", "aln": "MSDSISDSKSSELLNSTFYSSTSINTLDHARTFRNSLILKEISDQSLNSSIKPCESVLDRDVESSVLQRSFGESNARDSEVQTVNMTTSPSLSALADILNERSKYADQKTRKAQNIESSIIEEEEEAEEQNNSINYHEDITGSRLSVREEANENLAMTSPNLIDIDGSNSIQVAPLSLPSFEEPDFLSTPRVKPDSQGPRSKVSTRRTILERDNNLPVKREENTIINSETESTTHSAPFLKEDPKPSPPSSKLYNPKVRLNKAEARKYTDSSAQRTTSAGSVLEDTSMHKKKKSIFSFLKKKEPKPVIGNNSVTNEKNKMSSSSTFSMNIQTSLKTPEKLKKKSHSSSSIFNSFLKGKIETSDSPRKEPMRQKKRTPKSKDKKQDTEQIIDAASVLSTESPLLRKNHDDTPVKIDHVTRSIDQRKPTPLNMDLILGGDKQINTPLQEHVREDDDAKNDLQLPTKDNFLSLDYEAPSPAFSKHDTGEVLFPKFLDNHEVDSIVSLERTRSTKSNKRSSMNSQRRSLTDTLSIKAQSEGMFITEASSVVLSTPDLTKSPASSILKNGRFEYSDNFSREHSYEGTTNEDFLDIKDDSGPLKKDDIFLESIEQKFDQLVMASDEEKTEVERDVPKPREEPLKKDSERQSVFADDDNELISDIMEFASFINFGDDDLNLDLDLGDTTASYATETPEPVGNDEVNRSGTFDTRNNKEDSYKERETQSYSAAGATTYGDERQGQLHTFEQDGSEINDNEFENEDFNKHIEQPIEVTPRNNAYLPEFEPNRPVSMSFKGLKAPRMNTSFIDSMTPDSPVKSDLTSLGEVYVNSNNDQGVRFSSQIILYDTYGEFEYDRHPEISTCNQLTPQLAQMIKLELNELKS-AMEVHDDSRCYTHFY--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * . .. : . : * . * . :. :. :: ::. . *. : :.*:: . :* ::. .* : . : * * :*:: * *.: :*. * . *: : *.::. : . :* . . : :... . ..: . * . : . : :. * : * .: . **.*. ::. . .: : : : . : .*. . : : * * :: .. : * .. : .: : : : ::.* :. *** .* :. : : .*.* :.*. :. . :. * .*: . :: *:: . ..* :* : . :** . ** *: : ::.::: : . :.. : *:. : :***. : : :: :***:.: . .:**. *: ****:** ****: ** *:*: ", "identical_positions": 70, "similar_positions": 174, "identity": "7.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110103-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H426-1", "uniprot_id": "RIMS4_HUMAN", "id": "Q9H426-1", "name": "Regulating synaptic membrane exocytosis protein 4", "aln": "MERSQSRLSLSASFEALAIYFPCMNSFDDEDAG-DSRRLKGAIQRSTETGLAVEMPSRTLRQASHESIEDSMNSYGSEGNLNYGGVCLASDAQFSDFLGSMGPAQFVGRQTLATTPMGDVEIGLQERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGICIAKKKTKVARKSLDPLYNQVLLFPESPQGKVLQVIVWGNYGRMERKQFMGVARVLLEELDLTTLAVGWYKLFPTSSMVDPATGPLLRQASQLSLESTVGPCGERS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P60191-1", "uniprot_id": "RIMS4_MOUSE", "id": "P60191-1", "name": "Regulating synaptic membrane exocytosis protein 4", "aln": "MERSQSRLSLSASFEALAIYFPCMNSFDDEDAA-DSRRLKGAIQRSTETGLAVEMPSRTLRQASHESIEDSMNSYGSEGNLNYGGVCLASDAQFSDFLGSMGPAQFVGRQTLATTPMGDVEIGLQERNGQLEVDIIQARGLTAKPGSKTLPAAYIKAYLLENGVCIAKKKTKVARKSLDPLYNQVLLFPESPQGKVLQVIVWGNYGRMERKQFMGVARVLLEELDLTTLAVGWYKLFPTSSMVDPATGPLLRQASQLSLESTVGPCGERS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F2S0-1", "uniprot_id": "E7F2S0_DANRE", "id": "E7F2S0-1", "name": "", "aln": "MERSQSRLSLSASFEALAIYFPCMNSFDEDDGDPEGRRLKG-IQRSTETGLAVEMPSRTVRQASHESIEDSMNSYGSEGNLNYSGMCLASDAQFSDFLDGMGPAQFVGRQTLATTSMGDVEISLMERSGQLEVEVIQARGLIMKPGSKGPPAAYIKVYLLENGICIAKKKTKSVRKSLDPLYNQVLVFSESPQGKVVQVIVWGNYGRMDRKCFMGVARILLEELDLSSMVIGWYKLFPTSSMVDPTMAPLIRHSSQLSLESTVGPCCERS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************************::*. :.***** *****************:***********************.*:************..***************.******.* **.*****::****** ***** ******.******:******** .************:*.*******:***********:** ******:*******:::.:**************: .**:*::************ ***", "identical_positions": 225, "similar_positions": 33, "identity": "83.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110104-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y264-1", "uniprot_id": "ANGP4_HUMAN", "id": "Q9Y264-1", "name": "Angiopoietin-4", "aln": "--------------------------------------MLSQLAMLQGSLLLVVATMSVAQQTRQE------ADRGCETLVVQHGHCSYTFLLPKSEPCPPG----PEVSRDSNTLQRESLANPLHLG------KLPTQQVKQLEQALQNNTQWLKKLERAIKTILRSKLEQVQQQMAQNQTAPMLELGTSLLNQTTAQIRKLTDMEAQLLNQTSRMDAQMPETFLSTNKLENQLLLQRQKLQQLQGQNSALEKRLQALETKQQEELASILSKKAKLLNTLSRQSAALTNIERGLRGVRHNSSLLQDQQHSLRQLLVLLRHLVQERANASAPAFIMAGEQVFQDCAEIQRSGASASGVYTIQVSNATKPRKVFCDLQSSGGRWTLIQRRENGTVNFQRNWKDYKQGFGDPAGEHWLGNEVVHQLTRRAAYSLRVELQDWEGHEAYAQYEHFHLGSENQLYRLSVVGYSGSAGRQSSLVLQNTSFSTLDSDNDHCLCKCAQVMSGGWWFDACGLSNLNGVYYHAPDNKYKMDGIRWHYFKGPSYSLRASRMMIRPLDI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WVH6-1", "uniprot_id": "ANGP4_MOUSE", "id": "Q9WVH6-1", "name": "Angiopoietin-4", "aln": "--------------------------------------MLCQPAMLLDG-LLLLATMAAAQHRGPE------AGGHRQIHQVRRGQCSYTFVVPEPDICQLAPTAAPEALGGSNSLQRDLPASRLHLTDWRAQRAQRAQRVSQLEKILENNTQWLLKLEQSIKVNLRSHLVQAQQDTIQNQTTTMLALGANLMNQTKAQTHKLTAVEAQVLNQTLHMKTQMLENSLSTNKLERQMLMQSRELQRLQGRNRALETRLQALEAQHQAQLNSLQEKREQLHSLLGHQTGTLANLKHNLHALSSNSSSLQQQQQ---QLTEFVQRLVRIVAQDQHPVSLKTPKPVFQDCAEIKRSGVNTSGVYTIYETNMTKPLKVFCDMETDGGGWTLIQHREDGSVNFQRTWEEYKEGFGNVAREHWLGNEAVHRLTSRTAYLLRVELHDWEGRQTSIQYENFQLGSERQRYSLSVNDSSSSAGRKNSLAPQGTKFSTKDMDNDNCMCKCAQMLSGGWWFDACGLSNLNGIYYSVHQHLHKINGIRWHYFRGPSYSLHGTRMMLRPMGA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B722-1", "uniprot_id": "A0ACD6B722_DANRE", "id": "A0ACD6B722-1", "name": "", "aln": "MKVMENQARRRKRSNFISFQPCVSPSTELTFGSVFAVMRLARSGWHLALLLLAWVNLASSGNGNGQGRRGGGGERRRKLHRVQNGQCSYTFILPEMESCQEQ-------MSGTHGVQRDSPPADSEWS---------VQKLQHLETAMENNTQWLQKLENYIEQ--KTGMVHIQADAVHNQTATMLEIGTNLLSQTAEQSRKLNVVEAKVMNQTSRIAIQLLENSLSTNKLEKELISQLSEISKLRDKNSHLESKVLVLESQQRTELEDMREEKERLQDLVKRQTAAITALERQLRAASSNNSALQKQHQ---QLMKSVHTLIGMVSSGTG---ITPNEQRFRDCAEAYKSGHNTSGVYHIYIGDMTEPTKVFCDMVTSGGGWTVFQHRANGSVNFQKGWKDYKLGFGDPSGEHWLGNEAIHLITSQGQYSLRVELKDWEENGAYALYDKFQLTSEKQQYRLLLGSHSGTAGQKSSLALNGTGFSTRDADNDKCECKCALMMTGGWWFEACGMSNLNGIYYTIGHNIRKLNGIKWHHFRGPSYSLQSTSMMIRPTDF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.: . ** ..:: : : : . : *:.*:*****::*: : * .:: :**: . . .*::.:** ::****** ***. *: :: : : * : :***:.** :*:.*:.** * :**. :**:::*** :: *: *. *******.::: * ::.:*:.:* **.:: .**:::: :* .: .:: :* . : :*:.::: ::: *:. *.* **.*:: ** :: *: :. : . : *:**** :** .:**** * : *:* *****: :.** **::*:* :*:****: *::** ***: : *******.:* :* : * *****:*** . : *::*:* **.* * * : . *.:**::.**. :.* *** * ***:* **** :::*****:***:*****:** .: *::**:**:*:******:.: **:** . ", "identical_positions": 184, "similar_positions": 168, "identity": "33.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110106-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H6D3-1", "uniprot_id": "XKR8_HUMAN", "id": "Q9H6D3-1", "name": "XK-related protein 8", "aln": "MPWSS-RGALLRDLVLGVLGTAAFLLDLGTDLWAAVQYALGGRYLWAALVLALLGLASVALQLFSWLWLRADPAGLHGSQP----PRRCLALLHLLQLGYLYRCVQELRQGLLVWQQEEPSEFDLAYADFLALDISMLRLFETFLETAPQLTLVLAIMLQSGRAEYYQWVGICTSFLGISWALLDYHRALRTCLPSKPLLGLGSSVIYFLWNLLLLWPRVLAVALFSALFPSYVALHFLGLWLVLLLWVWLQGTDFMPDPSSEWLYRVTVATILYFSWFNVAEGRTRGRAIIHFAFLLSDSILLVAT---WVTHSSWLPSGIPLQLWLPVGCGCFFLGLALRLVYYHWLHPSCCWKPDPDQVDGARSLLSPEG-YQLPQNRRMTHLAQKFFPKAKDEAAS----PVKG--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C0T0-1", "uniprot_id": "XKR8_MOUSE", "id": "Q8C0T0-1", "name": "XK-related protein 8", "aln": "MPLSV-HHHVALDVVVGLVSILSFLLDLVADLWAVVQYVLLGRYLWAALVLVLLGQASVLLQLFSWLWLTADPTELHHSQL----SRPFLALLHLLQLGYLYRCLHGMHQGLSMCYQEMPSECDLAYADFLSLDISMLKLFESFLEATPQLTLVLAIVLQNGQAEYYQWFGISSSFLGISWALLDYHRSLRTCLPSKPRLGRSSSAIYFLWNLLLLGPRICAIALFSAVFPYYVALHFFSLWLVLLFWIWLQGTNFMPDSKGEWLYRVTMALILYFSWFNVSGGRTRGRAVIHLIFIFSDSVLLVTTS--WVTHGTWLPSGISLLMWVTIGGACFFLGLALRVIYYLWLHPSCSW--DPDLVDGTLGLLSPHRPPKLIYNRRATLLAENFFAKAKARAVLTEEVQLNGVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F2E5-1", "uniprot_id": "E7F2E5_DANRE", "id": "E7F2E5-1", "name": "XK-related protein", "aln": "MEKSLPFHYPLQDYLFTWIGLFFSLLDIAMDIWTVVSLYRSEAYVFMGLMIFFLLGSSVLLQVFSWLWYSDSLDELETEVEKFAERHDLIKPLHFLQLGVYLRYAGVIEISTKRFLHQKD---IFKESAYLNLDFKMLRLFETFAERTPQLILMMSLILQRGKLQLFTGLKFLTSAASIASSLAMYHNGIRICFDVK---CWTATAVYLLWNFLLIFPRVAALALFCSVFPCHIVAHFLSLWMVLVFVAWRQKTDFMESSGWQWLFKATVGLIWYFSWFNISKSNTKLKHAIYCSFLLLDMMMLLGFWSWKVTEYAGCWTSLNPAVVIPTLLGLYIIGNLVMMMNYKWFYTSYKQKTDELSKKIKEGTFKKAMPLGYSIETETVDEVPGVLLRSKIMAADFCF-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * * :. :. ***: *:*:.*. *:: .*:: :* :** **:***** . *. . : : **:**** * :. . :: : : :* **:.**:***:* * :*** *:::::** *: : : . : :* .*: :* **..:* *: * ::.:*:***:**: **: *:***.::** ::. **:.**:**:: * * *:** .. :**::.*:. * ******:: ..*: : *: *:: * ::*: **. : :.: : :. . :::* : :: * *::.* * . . :. : . . . .: ::* *. ", "identical_positions": 103, "similar_positions": 126, "identity": "25.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110106-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H6D3-1", "uniprot_id": "XKR8_HUMAN", "id": "Q9H6D3-1", "name": "XK-related protein 8", "aln": "-MPWSSRGALLRDLVLGVLGTAAFLLDLGTDLWAAVQYALGGRYLWAALVLALLGLASVALQLFSWLWLRADPAGLHGSQP----PRRCLALLHLLQLGYLYRCVQELRQGLLVWQQEEPSEFDLAYADFLALDISMLRLFETFLETAPQLTLVLAIMLQSGRAEYYQWVGICTSFLGISWALLDYHRALRTCLPSKPLLGLGSSVIYFLWNLLLLWPRVLAVALFSALFPSYVALHFLGLWLVLLLWVWLQGTDFMPDPSSEWLYRVTVATILYFSWFNVAEGRTRGRAIIHFAFLLSDSILLVAT-WVTHSSWLPSGIPLQLWLPVG--CGCFFLGLALRLVYYHWLHPSCCWKPDPDQVDGARSLLSPEG-YQLPQNRRMTHLAQKFFPKAKDEAAS----PVKG--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C0T0-1", "uniprot_id": "XKR8_MOUSE", "id": "Q8C0T0-1", "name": "XK-related protein 8", "aln": "-MPLSVHHHVALDVVVGLVSILSFLLDLVADLWAVVQYVLLGRYLWAALVLVLLGQASVLLQLFSWLWLTADPTELHHSQL----SRPFLALLHLLQLGYLYRCLHGMHQGLSMCYQEMPSECDLAYADFLSLDISMLKLFESFLEATPQLTLVLAIVLQNGQAEYYQWFGISSSFLGISWALLDYHRSLRTCLPSKPRLGRSSSAIYFLWNLLLLGPRICAIALFSAVFPYYVALHFFSLWLVLLFWIWLQGTNFMPDSKGEWLYRVTMALILYFSWFNVSGGRTRGRAVIHLIFIFSDSVLLVTTSWVTHGTWLPSGISLLMWVTIG--GACFFLGLALRVIYYLWLHPSCSW--DPDLVDGTLGLLSPHRPPKLIYNRRATLLAENFFAKAKARAVLTEEVQLNGVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "I3IS75-1", "uniprot_id": "I3IS75_DANRE", "id": "I3IS75-1", "name": "XK-related protein", "aln": "MEESFPFHYSLWEYLFSWVGLIFFLLDIVMDILTVVSLYQQENYVSMGLMIFFLLGSSVLLQIFSWVWYSDSLHELETKVEKFAKKKKLIKPLHFLQLG-VYLRYTGLMEISTTHFIRQTNTFTEGVTVYLSHDLQMLRLFEAFSESAPQLILMMTLTLQRGEFEIFTGLKLLSSVASIASTVTTYHRGMRAFLEDKHKMRWTSTAFYFLWNFLLMIPRVAALALFSSVFPCYITAHFLSSWMVLVLVAWSQKTDLMKR-HWEWLYRATVGLIWYFSWFNVSEGSIKLKSVVYYSLMGLDTIMLLGFWCWKVVEYADCWSMLNPYIVVPTLLGLYVIGILVEIIYYRWFHPTCDK----NKIAEPITAISDNAGSPAITDEGPSPPVTGAVKRSRTLAANFF--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.. :. ****: *: :.*. .*: .*:: :* :** **:***:* . *. . : : **:**** :* : : . .. . : :*: *:.**:***:* *::*** *:::: ** *. * : . : :*. .*: :: ***.:*: * .* : *:.:*****:**: **: *:****::** *:: **:. *:**:: * * *::* *****.*:. * *******: * : ::::: :: *:::*: . : . * :: : . :.:*: :.::** *:**:* : : . :* . :. : . . ::: *. ", "identical_positions": 104, "similar_positions": 126, "identity": "25.37%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110107-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AJG9-1", "uniprot_id": "A0A8I6AJG9_RAT", "id": "A0A8I6AJG9-1", "name": "Ankyrin repeat and SAM domain-containing protein 1A", "aln": "MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGSGGGS---GGGGLGSSSHPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHRDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQ---------------------NNDNETALHCAAQYGHTEVVKALLEELTDPTMRNNKFETPLDLAALYGRLEVVKLLLSAHPNLLSCS---------------------TRKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILLAAGIDVNIKDNRGLTALDTVRDLPSQKSQQIAALIEDHMTGRRSVKDVDKTSTAQLPLLSCTDAIAPKSLGSVEKAVTEPTLDSDILAEEEGPYEALYNAVSCHSLDSTASGRSSDRDSVNKEAEATGARAAGVRPRERPPPPAKPPPDEEEEERVDKKYLPLAASEGLALRPRMQGSAPQEEEEHPYELLLTAETKKLGTTDG---------RTEDHRQSGGSRSQDSVEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQLLTVPSQNHPE-SSQQDACQEASMQLEEPGEQSTGAPQPGILDQSKRAGLSAGLTALASRTYLDALTHTVPLHPAGAEEED--GSRSRAPPTSKPKAELKLSRSLSKSDSD--------------------LLTCSPTEDT-TMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQEQQ----------------------------KISGSRTLEQSVGEWLESIGLQQYESKLLLNGFDDVRFLGSNVMEDQDLREIGISD-------------------PQHRRKLLQAARSLPKVKALGYDGVSPASVPSWLDSLG---------------LQDYIHSFLSSGYSSIDTVKNLWELELVNVLKVHLLGHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLISQTSSPLSQNDSCTGR------------------------------------------------------------------------------------------------------------------------SADLLLPSVDTSRRRHDSLHDPGTTSR---------------------------------------AEHFRVQEEPSESK-LTLRPPSLAAPYAPVQSWQHRPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILS----------------------------ITYKGVKFMDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSR---TMAASAASMIETKSSKPVPKPRVGMRKSAVPVPPDSRCCHCHTCTTHRPSYLPLPSVSP----------GAKLEPPDSDQEAPSHASVSWIVDPKPDSKRSLSTN----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59672-1", "uniprot_id": "ANS1A_MOUSE", "id": "P59672-1", "name": "Ankyrin repeat and SAM domain-containing protein 1A", "aln": "MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGG-SGSGGGS---GGGGLGSSSHPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHRDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIQQGPSHTRVNEQNALEIRELKKYGPFDPYINAKNNDNETALHCAAQYGHTEVVKALLEELTDPTMRNNKFETPLDLAALYGRLEVVKLLLGAHPNLLSCS---------------------TRKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILLAAGIDVNIKDNRGLTALDTVRDLPSQKSQQIAALIEDHMTGKRSVKEVDRTSTAQLPLLSNTDAIAPMSQGSMEKTVTELILHFDTHADEEGPYEALYNAVSCHSLDSTASGRSSDRDSMNKEAEATGTRAAGVRPRERPPPPAKPPPDEEEEERVDKKYFPLAASEGLAVRPRIQSSAPQEEEEHPYELLLTAETKKLGTTDG---------RTEDHRQSGSGRSQDSVEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQLLTAPSQSHPE-SSQQDACHEASMQLEEPGVQGTEPPQPGVPDQSKRVGLPAGLTALASRTYLDALTHTVPLRPAGAEEEDQSGPRSRAPPTSKPKAELKLSRSLSKSDSD--------------------LLTCSPTEDA-TMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQEQQ----------------------------KISGSRTLEQSVGEWLESIGLQQYESKLLLNGFDDVRFLGSNVMEEQDLREIGISD-------------------PQHRRKLLQAARSLPKVKALGYDGVSPTSVPSWLDSLG---------------LQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVHLLGHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLISQTSSPLSQNDSCTGR------------------------------------------------------------------------------------------------------------------------SADLLLPSADTSRRRHDSLPDPGTASR---------------------------------------ADRFRVQEEPSETK-LTLRPPSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILS----------------------------ITYKGVKFIDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSR---TMAASAASMIETKSSKPVPKPRVGMRKSAL-------------------------------------------EPPDSDQEAPSHASVSWIVDPKPDSKRSLSTN----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92625-1", "uniprot_id": "ANS1A_HUMAN", "id": "Q92625-1", "name": "Ankyrin repeat and SAM domain-containing protein 1A", "aln": "MGKEQELLEAARTGHLPAVEKLLSGKRLSSGFGGGGGGGSGGGGGGSGGGGGGLGSSSHPLSSLLSMWRGPNVNCVDSTGYTPLHHAALNGHKDVVEVLLRNDALTNVADSKGCYPLHLAAWKGDAQIVRLLIHQGPSHTRVNEQ---------------------NNDNETALHCAAQYGHTEVVKVLLEELTDPTMRNNKFETPLDLAALYGRLEVVKMLLNAHPNLLSCN---------------------TKKHTPLHLAARNGHKAVVQVLLDAGMDSNYQTEMGSALHEAALFGKTDVVQILLAAGTDVNIKDNHGLTALDTVRELPSQKSQQIAALIEDHMTGKRSTKEVDKTPPPQPPLISSMDSISQKSQGDVEKAVTELIIDFDANAEEEGPYEALYNAISCHSLDSMASGRSSDQDSTNKEAEAAGVKPAGVRPRERPPPPAKPPPDEEEEDHIDKKYFPLTASEVLSMRPRIHGSAAREEDEHPYELLLTAETKKVVLVDG---------KTKDHRRSSSSRSQDSAEGQDGQVPEQFSGLLHGSSPVCEVGQDPFQLLCTAGQSHPDGSPQQGACHKASMQLEETGVHAPGASQPSALDQSKRVGYLTGLPTTNSRSHPETLTHTASPHPGGAEEGDRSGARSRAPPTSKPKAELKLSRSLSKSDSD--------------------LLTCSPTEDA-TMGSRSESLSNCSIGKKRLEKSPSFASEWDEIEKIMSSIGEGIDFSQERQ----------------------------KISGLRTLEQSVGEWLESIGLQQYESKLLLNGFDDVHFLGSNVMEEQDLRDIGISD-------------------PQHRRKLLQAARSLPKVKALGYDGNSPPSVPSWLDSLG---------------LQDYVHSFLSSGYSSIDTVKNLWELELVNVLKVQLLGHRKRIIASLADRPYEEPPQKPPRFSQLRCQDLLSQTSSPLSQNDSCTGR------------------------------------------------------------------------------------------------------------------------SADLLLPPGDTGRRRHDSLHDPAAPSR---------------------------------------AERFRIQEEHREAK-LTLRPPSLAAPYAPVQSWQHQPEKLIFESCGYEANYLGSMLIKDLRGTESTQDACAKMRKSTEHMKKIPTIILS----------------------------ITYKGVKFIDASNKNVIAEHEIRNISCAAQDPEDLCTFAYITKDLQTSHHYCHVFSTVDVNLTYEIILTLGQAFEVAYQLALQAQKSR---ATGASAAEMIETKSSKPVPKPRVGVRKSAL-------------------------------------------EPPDMDQDAQSHASVSWVVDPKPDSKRSLSTN----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q0Z5-1", "uniprot_id": "A0A8M9Q0Z5_DANRE", "id": "A0A8M9Q0Z5-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSQNVG----------------QASYPEHIETNGS---------------------------SEEAPNGR-------LKVISRSDSD--------------------LLASLDCEDVGPVFGQSDSLSDYAAQRKETEQMPSLDSEWDEIERIMTLIAG-IEIPEERQPALE------------------------DAAGSRVLEQSVGEWLEHVGFPQYESKLVLNGFDELRYMGSNVMEDEDLHEIGITD-------------------PGHRKKILHAAKSLPKVKALGCDG--STSLYSWLESLG---------------LGEYLHNFLSSGYRTLECVKNLWELEIVNVLKIGLLGHRKRIIASIAERPYEEAPSKTNRFSQLKIQDLLSQNASPLSYMDPYTSR------------------------------------------------------------------------------------------------------------------------SMDMLLPLGEAGRKSRALDQDGSISLRSF-------------------------------------GERSRSHDRHADRHSRQNRPTSQSHTYTTVSAWHHHPEKLITESCVYEARYLGSVIIRDLRGIESTQEACARIRKSKDHRK-GPVIILN----------------------------ITYKGVKFVDAATKAMVAEHEIQDISCAAQDPDDLCTFAYITKDMKSGYHFCHVFTTVEVTQTYEIILTLGQAFEVAYQMALQAQKARRHSSYAGPAPENIEIKTNRPTSQSRNSTRRSTGAPVLECRCCYCHTCSAHRPSYLPLPSISPGVQSHSSLLLPRQIDPLELETDLQSLGSTSWLYEPRSSSRPSSSTKHLQL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCM6-1", "uniprot_id": "Q9VCM6_DROME", "id": "Q9VCM6-1", "name": "Ankyrin repeat and SAM domain-containing protein 1A", "aln": "MGKDQEFLEAARNGNISHIEKVLTQK-------------------------------AKRAGPLASLRRGTGVNVQDSGGYSALHHACLNGHEDIVRLLLAHEASPNLPDSRGSSPLHLAAWAGETEIVRLLLTHPYRPASANLQT---------------------IEQETPLHCAAQHGHTGALALLLHHDADPNMRNSRGETPLDLAAQYGRLQAVQMLIRAHPELIAHLGTEALERGTPSPSSPASPSRAIFPHTCLHLASRNGHKSVVEVLLSAGVSVNLLTPSGTALHEAALCGKENVVRTLLKAGINLNATDNEGRTALDILREFPPHVTKHIVAVINNFRNQMDTDEGDEVIYRQHSGPP------NSGRGQNKHHSQQQPPLSNHYHFNSNNHLLNHSHSMQQSGYSKQRLSAGNGGPYNGGKSLDSALQPEDRFYQDLNAHSPLHSQNEMGGGYSVSPSSSLSSFEPASVSPRSRCSTGGLGQPMHMSTFAPAGPPKKPPRRNLSVSPTHAGPGQQFSYSSPSSQSQSQSHGHGQNQVRRQPASESPYSHQSHGSVGGMSFDETQLRERQRNDRLYASARQSTRSAIAGGMSLSSSNDMLDRQCSSSELNSETSVPNSSGDSPATNSMKRPIPAPRSSTTKLSKELLKSAESATLKSYNPNRKLKRNRNSSGANGAAKSNGGDENCEAKQQIPSSPTHYKQPPTPDHPPPSSSQAERTIHERIRPLSQEYKRRSALLQLQAAQQLMIETGSSPSKLLPTLSTPGYDYDDTVTVVPRCPAPSSGSLSSSISCSDHSLSHSTDYVEEFVSDVPFAGLLKGASQQLKEQPEVKLKIQEESKPQQTLPRVRPPIPTKPAIP-EKKFAKPPTTPTNQSLEANGNSSSDVVIKPPRSPSKSPSKTSNKSPVKSPGKSPAKSPGSGHSAARNSINLLSPFNAEEARKKISEIIENFGSGILNTSITPTHDIELDFEDMEVPNERRELATRLRAAGLLHLERILFENGYDNYKFVNNVFEEPDIPLLHIPERDAPKLLRFVQSLPPAEFQPQVPVKTQQENKQMGVATLQQWLNTIALPEYLEFFNKHLYNTIESVCGVWDVELQTVLEINKLGHRRRILQSLAYIRQMRDSDSKSQKTPLGENNETNQLTTNGNGTAREAPPRLPANPVHHRNSITGYRKSRPAPPPPAPPARKTAALQIRAPSELLLGLPANLRTTEWRHSAQTLLNEHINYEVQYLGSTVVKELRGTESTKKSIQKLKTSADGEVKSGSPLS---------------------------LAICHRGVEFKDVNSKRTICEHEIQNINCACQDSEDLRHFAYITKEQD--LHYCHVFLVESTDLASEIILTLGQAFEVAYQLALRDGITTTPELLLDNGMLQGEYCGGK---------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VC09-1", "uniprot_id": "Q9VC09_DROME", "id": "Q9VC09-1", "name": "PID domain-containing protein", "aln": "MGKDQHLLEASRAGDIKTVDKLLEHS-------------------------------SKRHGPLSSFRRSPSINCQDMNGYTSLHHACLNGHSNIVRLLLSHNALLDVPDIRGSTPLFLAAWAGHQDIVKMLLMHSPTGANPNAQT---------------------IENETPLHSGAQHGHNAVVAILLSYGADPAIRNNSFQTALDLAAQFGRLQVVQTLLRVYPDLILPY--KRLEDDNEELLG-CMPIKHIFTHTCLHLASRNGHKKVVETLLAAGVDVNILTNAGSALHEAALCGKKSVVVTLLKAGIYVHATDGNGRTALDILSDYPPHVTYDIVGAINEFTQAAREHQKPLVVENGTQSLP------KRLYEKNSQRQKVPPRQRKKQDHQANG--LSHSLS-----------------------SLDIFAKPPE-NYLQMKPIIHQKSCDNMS-DFRTNGSNLLTSYKPVYKQP-----------------------------------------------MLPSFRMDS---------------------DISNGSVPSRSYEYINLLR---------NGSHSDDNSAS-----TSSNSAVRQQAVATYVEMKLPTP--------------PVPKPR---TRINGEYNDYANVVPIEEGSCVAAVDNNNNSNGNG-------------------TKLRLVRHSPTPDYPPPTVTEAERTIFNFMQPATLRKNS-------------LLEPAESPR--------------------------TTNSVSS-------------DQVEEYVADIPFAGLFKGSTLNLS--SDVVDGIG--------------------AVPGDREFLQSPSMVRSAHVQNHRRSLS---------------------------KQRYSALGEDFSASR-------------VWAEIDTIFENIGN--------------------EVSTVEQEVEEFVEDPSSLSLE-----------------------------------------------------------------------------------------------------------------------------------DSRQ-------------------------------------------------------------SLHIRDPAELLLGRKPSAASSNWCHSPYTFIYGEIRYSLFYLGSTVIRKLQGTLSTRKSIQKLKIDEN--LKSAASVSDFSLLENCTTSTKYLKAANHQTRLNVDIAVSCVGVKFIDHDKKTAICCHDIENINCVCQDSEDLRYFAYITKEQD--LHYCHVFMVDSLELAKEIIMTLGQAFEVAYQLALSR-----------QGTSLNEEC------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :... .. . . : :. : . . . : : . :. *. : * : .: :. * . : : . : : . . . . .... : : :.: . : : . . . : . . * * . .:: *. **** :::.*:* **:.: ::: . : : : **:* * .* :. *:*.:*.*..**.:** ******: . *:**** . . : ***:***********:** . * ", "identical_positions": 55, "similar_positions": 98, "identity": "3.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110107-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P98105-1", "uniprot_id": "LYAM2_RAT", "id": "P98105-1", "name": "E-selectin", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNASCFLSALTFVLLIGKSIAWYYNASSE-LMTYDEASAYCQRDYTHLVAIQNKEEINYLNSTLR-----YSPSYYWIGIRK----VNNVWIWVGTQKPLTEEAKNWAPGEPNNKQRNEDCVEIYIQRPKDSGMWNDERCDKKKLALCYTASCTNTSCSGHGECVETIN---------SYTCKCHPGFLGPKCDQVVTCQEQE-------------YPDHGSLNCTHPFGLFSYNSSCSFSCERGYVP-------------------------------------------------------------------------------------------------SSMETT---------------------------VRCTSSGEWSAPAPACHVVECKALTQPAHGVRKCSSNPGSYPWNTTCTFDCEEGYRR---------------------------------------------------------------VGAQNLQCTSSGVWDNEKPSCKAVTCDAIPRPQNGSVSCSNSTAGALAFKSSCNFTCEHSFTLQGPAQVECSAQGQWTPQIPVCKASQCEALSAPQRGHMKCLP-----------------SASAPFQSGSSCKFSCDEGFELKGSRRLQCGPRGEWDSEKPTCAG-----------------------------------------------------------------------------------------------------------------------------VQCSSLDLP------GKMNMSCS---GPAVFGTVCEFTCPEGWTLNGSSILTCGATGRWSAMLPTCEAPANPPRP-----LVVALSVAATS-LLTLSSLIYVLK-RFFWKKAKKFVPASSCQSLQSFENYQGPSYII-----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q00690-1", "uniprot_id": "LYAM2_MOUSE", "id": "Q00690-1", "name": "E-selectin", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNASRFLSALVFVLLAGESTAWYYNASSE-LMTYDEASAYCQRDYTHLVAIQNKEEINYLNSNLK-----HSPSYYWIGIRK----VNNVWIWVGTGKPLTEEAQNWAPGEPNNKQRNEDCVEIYIQRTKDSGMWNDERCNKKKLALCYTASCTNASCSGHGECIETIN---------SYTCKCHPGFLGPNCEQAVTCKPQE-------------HPDYGSLNCSHPFGPFSYNSSCSFGCKRGYLP-------------------------------------------------------------------------------------------------SSMETT---------------------------VRCTSSGEWSAPAPACHVVECEALTHPAHGIRKCSSNPGSYPWNTTCTFDCVEGYRR---------------------------------------------------------------VGAQNLQCTSSGIWDNETPSCKAVTCDAIPQPQNGFVSCSHSTAGELAFKSSCNFTCEQSFTLQGPAQVECSAQGQWTPQIPVCKAVQCEALSAPQQGNMKCLP-----------------SASGPFQNGSSCEFSCEEGFELKGSRRLQCGPRGEWDSKKPTCSAV--------------------------------------------------------------KCDDVPRPQNGVMECAHATTGEFTYKSSCAFQCNEGFSLHGSAQLECTSQGKWTQEVPSCQVVQCPSLDVP------GKMNMSCS---GTAVFGTVCEFTCPDDWTLNGSAVLTCGATGRWSGMPPTCEAPVSPTRP-----LVVALSAAGTS-LLTSSSLLYLLM-RYFRKKAKKFVPASSCQSLQSFENYHVPSYNV-----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P98106-1", "uniprot_id": "LYAM3_RAT", "id": "P98106-1", "name": "P-selectin", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGCPK---------------------GSWKPRLRSVVLG---AAQLIWLSALISELVNRKKVATWTYNYSTK-AYSWNNSRAFCKRHFTDLVAIQNKNEIAHLNDVIP-----YVNSYYWIGIRK----INNKWTWVGTNKTLTAEAENWADNEPNNKRNNQDCVEIYIKSNSAPGKWNDEPCFKRKRALCYTASCQDMSCNSQGERIETIG---------SYTCSCYPGFYGPECEYVQECGKFD-------------IPQHVLMNCSHPLGDFSFSSQCTFSCPEGYDLNGPSEMQCLASGIWTNNPPQ---------------------------------------------------------------CKAVQCQSLEAPLHGTMDCTHPLAAFAYDSSCKFECQPGYRMRGSDILHCTDSGQWSEPLPTCEAIACEPLESPLHGSMDCFPSTGAFGYNSSCTFRCTEGFVLMGNDAIHCADLGQWTAPAPVCEALQCQEFP-VPSKAQVSCSDPFGPLKYQSACSFSCDEGSLLVGASVIRCLATGHWSEAPPECQAVSCTPLLSPENGTMTCIQP-LGHSNYKSTCQFMCDEGFYLSGPERLDCSPSGHWTGSPPMCEAIKCPEIFAPEQGSLDCS------------------HVHGEFSVGSTCHFSCNEEFELLGSRNVECTVSGRWSAPPPTCKG--VTSLPVP----------------------------------------------------SVRCPALTTPGQGTMSCRHHLE-SFGPNTTCYFGCKTGFTLRGANSLRCGASGQWTAVTPVCRAVKCSELHMD------TAVAMNCSNPWGNFSYGSTCAFHCPEGQSLNGSARTTCGEDGHWSDAMPTCQAGTLTIQE---ALTYLGGALASTSGLAVGGTLLALLR-KRLRKKDDGKCPLNPHSHLGTYGVFTNAAYDPTP---------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01102-1", "uniprot_id": "LYAM3_MOUSE", "id": "Q01102-1", "name": "P-selectin", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGCPK---------------------GSWTPRLRSVILG---GAQLIWFSALISELVNQKEVAAWTYNYSTK-AYSWNNSRVFCRRHFTDLVAIQNKNEIAHLNDVIP-----FFNSYYWIGIRK----INNKWTWVGTNKTLTEEAENWADNEPNNKKNNQDCVEIYIKSNSAPGKWNDEPCFKRKRALCYTASCQDMSCSNQGECIETIG---------SYTCSCYPGFYGPECEYVKECGKVN-------------IPQHVLMNCSHPLGEFSFNSQCTFSCAEGYELDGPGELQCLASGIWTNNPPK---------------------------------------------------------------CDAVQCQSLEAPPHGTMACMHPIAAFAYDSSCKFECQPGYRARGSNTLHCTGSGQWSEPLPTCEAIACEPPEIPIHGSMDCVPSTGTFGYNSSCTFLCAEGFVLKGNDAIQCADSGQWTAPAPFCEALQCPEFP-VPSKAQVNCSDPFGTLTYQSVCSFSCDEGSLLVGASVIRCLATGHWNGAPPECQAVSCAPMLSPENGSMTCVQP-LGNSTYKSTCQFMCDEGFYLSGPERLDCSPSGHWTGTPPTCEAIKCPGIFAPEQGNLDCS------------------HVHGEFGVGSICHFSCNEDFELLGSENVECTVSGRWSAPPPTCKG--ITSLPAP----------------------------------------------------AVRCPALTTPGQGTMSCQHHLG-SFGPNTTCYFGCKTGFTLRGANSLRCRASGQWTAVTPMCRAVKCSELHMD------TAVAMNCSNPWGNFSYGSTCTFQCPEGQSLNGSVRATCREDGHWSDAMPTCQAGTLTIQE---ALTYLGGAVASTTGLAVGGTLLALLR-KRLRKKDDGKCPLNPHSHLGTYGVFTNAAYDPTP---------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16109-1", "uniprot_id": "LYAM3_HUMAN", "id": "P16109-1", "name": "P-selectin", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MANCQI---------------------AILYQRFQRVVFG---ISQLLCFSALISELTNQKEVAAWTYHYSTK-AYSWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLP-----YYSSYYWIGIRK----NNKTWTWVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIG---------NYTCSCYPGFYGPECEYVRECGELE-------------LPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPER-GNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLP-VPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQP-LGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCS------------------DTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKG--IASLPTP----------------------------------------------------GVQCPALTTPGQGTMYCRHHPG-TFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVN------KPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGPLTIQE---ALTYFGGAVASTIGLIMGGTLLALLR-KRFRQKDDGKCPLNPHSHLGTYGVFTNAAFDPSP---------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T6Z7-1", "uniprot_id": "A0AB32T6Z7_DANRE", "id": "A0AB32T6Z7-1", "name": "E-selectin", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQCNCLNSKSHLTVILYALLCKFPFRFHANKTELCQKKMVL---LVHITLFSGSLVFMTGMYNVNAWTYHYNIDSKLDWTAARQWCQTHFTDMVAIQNQAEIAYLNEILP-----FHRAYYWIGIRK----IDGHWTWVGTKKRLTVEAANWATNEPNNQGTGEDCVEIYIKRNKDTAKWNDERCSKKKATVCYLASCTEISCSEHARCVETIG---------NYTCQCDAGFMGPRCEEVVQCQPVE-------------NPQQGLVKCDGAFGEFNFNSSCQFQCATGFNLVGAERIHCLTTGHWNDTLPVCQAVKCQAIIDAPRGWTMICTHPLSMNSFNSSCEFECKEGFELNGSKTTWCDHTGHWTDKAPTCTVVTCNPLLAPANSSLACADPLGKSSFRSSCNVTCDEGYKLRGRAALTCQREGNWSAPLPVCEVVKCDSLKPIANGSYQCHDSVDEFSYGSTCWFKCDSGFVHNGTNSTHCTKQGNWSHISPICHAVQCPPLSDTPKYGSVSCVHPLSTNSYNSSCEFKCEEGLVLRGTDSTHCDHTGHWTNTAPICTAVACDPLVTPVNSNLTCANP-LGKFSFRTSCEVICEVGYKLRGDTTLNCLSNGNWSAPTPACKVIRCEALESVHHGSVHCH------------------DLLEEFSYGSECWLECEAGFTLNGTNSTYCTSQGKWKQELSVCQAQQCSSLTDPSHGSLTCTHPHGQFSFGTVCEVSCQAGFKLHGTPKMECLEMGKWTDTPPFCLAQECPLLSAPENGWMNCSHPHS-LFSYESQCLLGCETGFELTGEPDIQCSASGNWSQEMPSCAVVHCEPLWLTHLSDLGPPPSMNCSHPHGNFSFGSQCMFWCANSHELNGTSQLVCTSNGYWTHSPPICVVKEMSVSAS--MLIYAAVGAVSSAGLLLLGGLIFLLT-RQITKK--AHYSLNKSSLEGDL----NLAFELN----------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYR4-1", "uniprot_id": "Q9VYR4_DROME", "id": "Q9VYR4-1", "name": "", "aln": "MFCCNIPVDASVATSTSTSISTYPLQRATKRAMTPPNAMALIMLLLLALCAAGNGQICGPPAVPLNAKVRTITVDSQIAEAHYECDAGYELFGPSAVKCDRRTGWDRDLPFCGVNVAYRKPVNQSSYTRSGPASYANDGKPGNKNPDGQECSETQKEPSPWWRVDLLTPQAVHVVRITTRGCCGHQPLQDLEIRVGNSSADLQRNPLCAWYPGTLDEGVVKTFTCARPLVGQYVAIQLVGVEGSLSLCEVETFTNDEFSVDRCLSPKIGVDTVVTTFSKTCYDFHITKGESFDKAQAICKQTGGDLVHDFRGATSSYILSELERRKSELKPQLVWIGAQKEPGITSRTWKWVNG---DVVQKPTWGKDQPNNYNGEQNCVVLDGGRN---WLWNDVGCNLDYLHFICQHSPLSCGSPDAQQNTTVMGKKFTLGEKIQYTCPKGHSLLGQTERECRLDGTWSGSSPTCKYVDCGSLPELKFGSIHMSEERTSFGVVATYSCHENYTLIGNENRTCAMDGWSGKQPE----------------------------------------------------------------CLVDWCPDPQPIAGGDVRFNDKRAG----STATYVCEPGYVLVGEAIISCGLGGEWSSKTPSCRFVDCGAPARPNRGIAILLN--GTTTVNSVVKYECDEDHWLDGQSELYCTREGKWSGEAPVCELVTCETPS-----VPSGSFVIGYDYNVHSKIQYNCDPGHIMHGTPVLECLDSGEWSADAPYCEYIDCGTILPIPYGSHKYVTN---TTYVGSEVVFSCSQSHKLSGVLKRTCLESAVWSDASPKCEEIRCPEPKLAAHSLLSVTGNDRMYGRTLIRTSESSQNTAQTYKIGALAKYRCERGYKMVGEALATCTDSGQWSGTIPECVYVECGAPEGINNGKVVLATNATYYGAAVLYECNVNFKLNGVSRRLCTEHG-------NWSHEAPECVEVVCDTPNINENLIVEAGPRAVGSVATFKCAKGRIMMGNDTRVCQKNGKWTGKSPTCRPVDCGRPLAIE--------NGRVIVVNDSTLYGGSAEYHCIPNYNRIGQYLRKCTEDGAWSGKQPRCELATAEGQETSELGTGVGIGATVIVALLVIFGLIFLYRNKARPVKNTENVQAAETKDERNAAVMSYSTLEANNRMHMDNNPSATFNTFHGGAGGRSNGGGNPDANSNGERLNNNRSENIYDQIPNEQFYDAPYEMRTNDEVYEPEPVASNVITINGISVR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : *. : : *: .:* . :: . : *** :* . * **. . : .*. .:*** ::** : *** * . * . .. . .:. .*** .: * . *: . . .:. . : * .: . : : * *.** * *. : * . .* .: : * ... *: .* :* * * * : * .: . . : . *. .. * * * .. *: * *: :* :. : : *: . *: : : * * *.*. . * *.* . :* . : * . * * * *: * * . . . * *: : : * . : ", "identical_positions": 71, "similar_positions": 106, "identity": "5.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110110-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1F2-3", "uniprot_id": "MICA2_RAT", "id": "D4A1F2-3", "name": "[F-actin]-monooxygenase MICAL2", "aln": "-----------------------------------------MGENEDEKQAQASQVFENFVQATTCKGTLQAFNILTCLLDLDPLDHRNFYTQLKSKVNTWKAKALWHKLDKRGSHKEYKRGKACSNTKCLIVGGGPCGLRTAIELAYLGAKVVVVEKRDTFSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGSIDHISIRQLQLILFKVALMLGVEIHVNVEFVRVREPPKDQENRKIGWRAEFLPADHALSNFEFDVIIGADGHRNTLEGFRRKEFRGKLAIAITANFINRNSTAEAKVEEISGVAFIFNQKFFQDLKEETGIDLENIVYYKDSTHYFVMTAKKQSLLDKGVILNDYIDTEMLLCAENVNQDNLLSYAREAADFATNYQLPSLDFAINHNGQPDVAMFDFTSMYASENAALMRERQAHQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMVKSWDQGTP-PLEVLAERESLYRLLPQTTPENINKNFEQYTLDPATRYPNLNVHCVRPHQVKHLYITKEMDRFPLERWG-------SVRRSASLSRRESDIRPN--KLLTWCQQQTKGYQHV-RVTDLTTSWRSGLALCAIIHSFRPELINFDSLNENDVVENNQLAFDVAKREFGILPVTTGKEMASTQEPDKLSMVMYLSKFYELFRGTPLRPMDSRRKNYGENADFGLGKTFFQNNYLNLTLPRKRTP--------------RVDAQTEENDVNKRRRQGFNNLEELPAFSSRSLGSSQEY--AKESGNQNKVKYMANQLLAKFEENTRNPSALKQDCPRVSGMGKPVLCSASRPPGTSHCPKLEESTPRLPPPLKR---------QFSSTVATGQVLRELN-QVPASGECPGRPWR-----ARAKSDLQLGGAENLATLPPTCQGALALSGVLRRLQQVEEKVLQKRAQNLANREFHTKNIKEKAAHLASMFGHGDLPQDKLLSKRVPHAHPPSPPSCLPSPDPAAAPSPPAADSVSPARKV--------------------LTVGKVSSGIGAAAEVLVNLYLNDHRPKTQATSPDLESLRKAEFPLSLGGRDTCYFCKKRVYVMERLSAEGHFFHRECFRCSVCAAILRVAAYAFDCDE--GKFYCKLHFAHCKTSSKQRKRRAELNQQREEEGTWPEQEAARRDVPAESSCAVAAISTPE----------------------------------------------------------------------------------------------------------GSPPDEPISPKKSKSVPKPNSRPMEVEATSPRPSEWTSVRIGPGQD--GQDVLAVRVLVTSEDSSSDTESDSGSIIGPCTEACEERPRLPESPPLSQPLTRHISLRETLTQPVSLLLHHKEPQAVPGLQRAYSLQS--PSKYQNWRRKFQSNSTPMNQRA------------------------------------------------------------LSPPKEPPPS----SSSSSPSLPSSFSSASVPGHTTDDSSSPQVTYNLHSPQISRDDVSP----------------------TPIYLRRARAQGITKEIPLYLPHSPMLESTEHCLVSPDGEELRSPEEISASDGCQKALALGNS--------------------------ESTHKDSYPVSGKDPYLPNQMLALGAAGNTGDLSEESRMGQTGGAELSKERKLGLKKLVLTEEQKTMLLDWNDYTQE---HKAGERLAQEKAENGRGN-SLKPICSSTLSQAVKEKLLSQKKALGETRTPAAKAPREREVPPPKSPLRLIANAIFR---SLLPSSEAGKKTSSKPETKTLPR---------------GQPHAFTRSFSFRKLGSSKDGDQQSPGRHMAKKASAFFSLASPTSKAAQASDLSPPNPILRSRSLPNRPS-------------------------------------------KMFFATTSLPPSSKVEDVPTLLEKVSLQD---------------------------------------------------AAQGPKKGASHISPLGLKDKSFESFLQECKERKDIGDFFNSPKEKGPPGNRVPSLEKLVQPVDSTSMGQVAHPSSTGQDAQAAVRTQAGKEGSSLVSSLVLVSGPGAPVTEDTSSPTSSSAEEDVETQLSSRLKEK-IPRRRRKLE---KQMAKQEELKRLHKAQAIQRQLEEVEERQRTSEIQGVR-----LEKVLRGETADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLRQKMLKDEGQKDEN-------------------------------------DLKEEQEIFEEMMQVIEQRNKLVDSLEEQRIKERTQDQHFENFVLSRGCQLSRT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BML1-4", "uniprot_id": "MICA2_MOUSE", "id": "Q8BML1-4", "name": "[F-actin]-monooxygenase MICAL2", "aln": "-----------------------------------------MGENEDEKQAQASQVFENFVQATTCKGTLQAFNILTCLLDLDPLDHRNFYSQLKSKVNTWKAKALWHKLDKRGSHKEYKRGKACSNTKCLIVGGGPCGLRTAIELAYLGAKVVVVEKRDTFSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGSIDHISIRQLQLILFKVALMLGVEVHVNVEFVRVLEPPEDQENQKVGWRAEFLPADHALSDFEFDVIIGADGHRNTLEGFRRKEFRGKLAIAITANFINRNSTAEAKVEEISGVAFIFNQKFFQDLKEETGIDLENIVYYKDSTHYFVMTAKKQSLLDKGVILNDYIDTEMLLCSENVNQDNLLSYAREAADFATNYQLPSLDFAINHNGQPDVAMFDFTSMYASENAALMRERQAHQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMVKSWDQGTP-PLEVLAERESLYRLLPQTTPENINKNFEQYTLDPATRYPNLNLHCVRPHQVKHLYITKEMDRFPLERWG-------SVRRSVSLSRRESDIRPN--KLLTWCQQQTKGYQHV-RVTDLTTSWRSGLALCAIIHSFRPELINFDSLNEDDAVENNQLAFDVAKREFGILPVTTGKEMASTQEPDKLSMVMYLSKFYELFRGTPLRPMDSWRKNYGENADFGLGKTFIQNNYLNLTLPRKRTP--------------RVDTQTEENDMNKRRRQGFNHLEELPSFSSRSLGSSQEY--AKESGSQNKVKHMANQLLAKFEENTRNPSVVKQDCRRVSGIGKPVLCSASRPPGTSCCPKLEESTPRLPPPLKR---------QFSSTVATGQVLRELN-QVPASGECPSRPWR-----ARAKSDLQLGGVENLATLPRTCQGALALSGVLRRLQQVEEKVLQKRAQNLANREFHTKNIKEKAAHLASMFGHGDLPQDKLLSKRVPHAHPPSPPSCLPSPHPAAASSPPAADSVSPARKVVA--------LNHRLPPPLHLTVGKVSSGIGAAAEVLVNLYLNDHRPKTQATSPDLESPRK-AFPLSLGGRDTCYFCKKRVYMIERLSAEGHFFHQECFRCSVCSATLRLAAYAFDCDE--GKFYCKPHFVHCKTSSKQRKRRAELNQQREEEGTWQEQEAPRRDVPTESSCAVAAISTPE----------------------------------------------------------------------------------------------------------GSPPDEPISPKKPKSVPEPNPRDVEAEATSPRPSEWTSVRISPGEDTVRQDVLAVRVLVTSEDSSSDTESDYGSITAPCAGAYEERPQLPESPPLSKPLTRHISLRENLTQPVSLL--HEEPQALPALQRAHSLQSPTPSKYQNWRRRFQSNSTPMNQRA------------------------------------------------------------PSPPKEPPPPP---SLSSSSSLPSSFSSASVPGHTADDSSSPQVTYNLHSPQISRGDVSP----------------------TPIYLRRARAQGIVKEIPLYLPHSPMLESTEDCLVEPGRESLRSPEEISSSEGCQEARALGN-----------------------------TRSIQHPILGKDQYLPNQNLALGAAGNPGDPREESRMGQPGGPELSKERKLGLKKLVLTEEQKNKLLDWSDCTQE---HKTGEQLSQESAENIRGG-SLKPTCSSTLSQAVKEKLLSQKKALGGMRTPAVKAPQEREVPPPKSPLKLIANAILR---SLLHNSEAGKKTSPKPESKTLPR---------------GQPHA--RSFSLRKLGSSKDGDQQSPGRHMAKKASAFFSLASPTSKVAQASDLSLPNSILRSRSLPSRPS-------------------------------------------KMFFSTT---PHSKVEDVPTLLEKVSLQD---------------------------------------------------ATHSPKTGASHISSLGLKDKSFESFLQECKQRKDIGDFFNSPKEEGPPGNRVPSLEKLVQPVGSTSMGQVAHPSSTGQDAR---KLEGGEGGSSLVSSLVLVSDPVAPVTEATSSPTSSSAEEEADSQLSLRIKEK-ILRRRRKLE---KQSAKQEELKRLHKAQAIQRQLEEVEERQRTLAIQGVK-----LEKVLRGEAADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLRQKMLKDEGQKDEN-------------------------------------DLKEEQEIFEEMMQVIEQRNKLVDSLEEQRVKERTQDQHFENFVLSRGCQLSRT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94851-7", "uniprot_id": "MICA2_HUMAN", "id": "O94851-7", "name": "[F-actin]-monooxygenase MICAL2", "aln": "-----------------------------------------MGENEDEKQAQAGQVFENFVQASTCKGTLQAFNILTRHLDLDPLDHRNFYSKLKSKVTTWKAKALWYKLDKRGSHKEYKRGKSCTNTKCLIVGGGPCGLRTAIELAYLGAKVVVVEKRDSFSRNNVLHLWPFTIHDLRGLGAKKFYGKFCAGSIDHISIRQLQLILFKVALMLGVEIHVNVEFVKVLEPPEDQENQKIGWRAEFLPTDHSLSEFEFDVIIGADGRRNTLEGFRRKEFRGKLAIAITANFINRNSTAEAKVEEISGVAFIFNQKFFQDLKEETGIDLENIVYYKDCTHYFVMTAKKQSLLDKGVIINDYIDTEMLLCAENVNQDNLLSYAREAADFATNYQLPSLDFAMNHYGQPDVAMFDFTCMYASENAALVRERQAHQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMVKSWNQGTP-PLELLAERESLYRLLPQTTPENINKNFEQYTLDPGTRYPNLNSHCVRPHQVKHLYITKELEHYPLERLG-------SVRRSVNLSRKESDIRPS--KLLTWCQQQTEGYQHV-NVTDLTTSWRSGLALCAIIHRFRPELINFDSLNEDDAVENNQLAFDVAEREFGIPPVTTGKEMASAQEPDKLSMVMYLSKFYELFRGTPLRPVDSWRKNYGENADLSLAKSSISNNYLNLTFPRKRTP--------------RVDGQTGENDMNKRRRKGFTNLDEPSNFSSRSLGSNQECGSSKEGGNQNKVKSMANQLLAKFEESTRNPSLMKQE-RRVSGIGKPVLCSSSGPPVHSCCPKPEEATPSPSPPLKR---------QFPSVVVTGHVLRELK-QVSAGSECLSRPWR-----ARAKSDLQLGGTENFATLPSTRPRAQALSGVLWRLQQVEEKILQKRAQNLANREFHTKNIKEKAAHLASMFGHGDFPQNKLLSKGLSHTHPPSPPSRLPSPDPAASSSPSTVDSASPARKEKKSPSGFHFHPSHLRTVHPQLTVGKVSSGIGAAAEVLVNLYMNDHRPKAQATSPDLESMRK-SFPLNLGGSDTCYFCKKRVYVMERLSAEGHFFHRECFRCSICATTLRLAAYTFDCDE--GKFYCKPHFIHCKTNSKQRKRRAELKQQREEEATWQEQEAPRRDTPTESSCAVAAIGTLE----------------------------------------------------------------------------------------------------------GSPPDEPTSPKRPKSISEPQHSDAEGDAASPLPSEWTSVRISPGEEAAGQDVLAVRVLVTSEDSSSDTESDYGGSEGSHTEPCEEKPWRPGSPHLP-----HTSLGEALSRAVSPQCPEEPRAVHAALQRANSFQSPTPSKYQNWRREFWWSLTPVNKRT------------------------------------------------------------MSPPKDPSPSLPLPSSSSHSSSPPSSSSTSVSGNAPDGSSPPQMTASEPLSQVSRGHPSPP---------------------TPNFRRRAVAQGAPREIPLYLPHHPKPEWAEYCLVSPGEDGLSDPAEMTSDECQPAEAPLGDI--------------------------GSNHRDPHPIWGKDRSWTGQELSPLAGEDREKGSTGARKEEEGGPVLVKEK-LGLKKLVLTQEQKTMLLDWNDSIPESVHLKAGERISQKSAENGRGGRVLKPVRPLLLPRAAGEPLPTQRGAQEKMGTPAEQAQGERNVPPPKSPLRLIANAIRRSLEPLLSNSEGGKKAWAKQESKTLP------------------AQACTRSFSLRKTNSNKDGDQHSPGR-------------------NQSSAFSPPDPALRTHSLPNRPS-------------------------------------------KVFPALRS-PPCSKIEDVPTLLEKVSLQEN-----------------------------------------------FPDASKPPKKRISLFSSLRLKDKSFESFLQESRQRKDIRDLFGSPKRKVLPEDSAQALEKLLQPFKSTSLRQAAPPPPPPPPPPPPPPTAGGADSKNFP-----LRAQVTEASSSASSTSSSSADEEFDPQLSLQLKEKKTLRRRKKLEKAMKQLVKQEELKRLYKAQAIQRQLEEVEERQRASEIQGVR-----LEKALRGE-ADSGTQDEAQLLQEWFKLVLEKNKLMRYESELLIMAQELELEDHQSRLEQKLREKMLKEESQKDEK-------------------------------------DLNEEQEVFTELMQVIEQRDKLVDSLEEQRIREKAEDQHFESFVFSRGCQLSRT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PQ90-1", "uniprot_id": "A0A8M9PQ90_DANRE", "id": "A0A8M9PQ90-1", "name": "F-actin monooxygenase", "aln": "----------------------------------------MMGEAEDEK-NRTGRLFENFVQATDCKSTLQAFNILCGSLELDPLEHSSFYGSLKSSLTCWKAKALWSKLDKRASHKEYKKGRACEGIKCLIIGGGPCGLRTAIELAFLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRALGAKKFYGKFCAGAIDHISIRQLQLMLLKIALILGVEFHVNVEFVKLAEPPEDQENEGPGWRADIRPADHPVADFDFDVVVGADGRRNSLEGFRRKEFRGKLAIAITANFTNRNTTAEAKVEEISGVAFIFNQKFFQDLRQETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIIHDYIDTEALLNSENVNQEALLVYAREAADYATHYQLPTLDYAMNHCAQPDVAMFDFTSMYASENAALVRERFGHSVLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMVKSWAQGRN-PLEVLAERESLYRLLPQTTPENIAKNFDLYTIDPGTRYPNLNSNCVRPHQVRNNYICGEMKLCSLERAS-------TIRRPVNLARRESEIRPG--RLLTWCQKQTEGYRDV-NVTDLTSCWSNGLALCALIHRFRPQLIDYDSLNEQDCARNLQLAFDVAEKEFGIKPFITGKELASGQEPDKSSMSIYLSKFYELFRGTPLPPSDSKRDDDANNEKCPSGSPKSVYKSLSLQ-PRKRIP--------------KNDKKVEDTDAISKRRRKLNYLEETTKSYNQSSSVSSEG----RELKENKVKFMATQLLAKFEDSTASCSLRRQS----DCNGERPPRPPSLDMTDSSFFNIIKKKVPPPPPPKK---------QFPSIALVQHSDESSDPLFLSLHSSPLNPRRKPLHPSHTHTHAQPPHTESDTESSGSRTAVLAVTAMLQRLQRVEEEISQRKAQTQKAREFHKKSIKEKAVHLSALFSG-------------------------------------------------------------------------------------------------EASAPDQTD---------------------------------------------------------------------------------RSQTGLLDKQLHEE----KRESAKRLLQPSSSIHLP------------------------------------------------------------------------------------------------------------------------SPNPLTTTSYPLTQSTATSCPPPILSSCPSFPIQ-------------------QTSSSTVHHHSNSIIFHPIPECTAPIHLSFS-----------------------------------FSSAFSLSS--KSKSE--------TCSGVNMQR------------------------------------------------------------QSE-----------SSSQMCDSCSSISSFTVRKQT--------------------------------------------------------------------------------------DVPQSNEDLSAT--------------------------------------------------------------------------------------KQRTVGKVSLRVG-----------------------------------------------------------------ARADALVTLYENDHRP-------------------------------------------------------------------------------------------------------QTSSSGTPPSIKR--EFPQTLG-------------------------------------------DVCHACKK---------RVFVVERLSAEG------------------------------------------------------------FHFHRECFRCETCRAPLRQG------GHCFHSEEGKLYCKLHFAQRKSLVKNGRTETLHTTCN-----------------------------------DGSHHGSSWTPESHEDHLQAESAG-----------------ILSCVKRSLCWPLHVSQTVC-----AVPRRVCTWLHG--------------------------------KVSAARVHLMDNAGDYAFLYELLSVG---LPLLAILHEQLLQMYAEAEPF-------------------------------------NLQPLQHWLEEHMG---------------------------HWVLA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86BA1-1", "uniprot_id": "MICAL_DROME", "id": "Q86BA1-1", "name": "[F-actin]-monooxygenase Mical", "aln": "MSRQHQRHHQQHHHLPPHQQPQQQMPQQQQQLTAQQQQQQQLLMAEHAAAAEAAELFDLLCVATTMRQILALHRAMCEAVGLRPSPLNDFYPRLKAKVRSWKAQALWKKFDARAAHRVYGKGAACTGTRVLVIGAGPCGLRTAIEAQLLGAKVVVLEKRDRITRNNVLHLWPFVITDLRNLGAKKFYGKFCAGSIDHISIRQLQCMLLKVALLLGVEIHEGVSFDHAVEPSGD----GGGWRAAVTPADHPVSHYEFDVLIGADGKRNMLD-FRRKEFRGKLAIAITANFINKKTEAEAKVEEISGVAFIFNQAFFKELYGKTGIDLENIVYYKDETHYFVMTAKKHSLIDKGVIIEDMADPGELLAPANVDTQKLHDYAREAAEFSTQYQMPNLEFAVNHYGKPDVAMFDFTSMFAAEMSCRVIVRKGARLMQCLVGDSLLEPFWPTGSGCARGFLSSMDAAYAIKLWSNPQNSTLGVLAQRESIYRLLNQTTPDTLQRDISAYTVDPATRYPNLNRESVNSWQVKHLVDTDDPSILEQTFMDTHALQTPHLDTPGRRKRRSGDLLPQGATLLRWISAQLHSYQFIPELKEASDVFRNGRVLCALINRYRPDLIDYAATKDMSPVECNELSFAVLERELHIDRVMSAKQSLDLTELESRIWLNYLDQICDLFRGEIPHIKHPKMDFSDLRQKYRINHTHAQPDFSKLLATKPKAKSPMQDAVDIPTTVQRRSVLEEERAKRQRRHEQLLNIGGGAAGAAAGVAGSGTGTTTQGQNDTPRRSKKRRQVDKTANIEERQQRLQEIEENRQERMSKRRQQRYHQTQNFYKSLQLLQAGKLLREGGEAGVAEDGTPFEDYSIFLYRQQAPVFNDRVKDLERKLLFPDRERGDIPSALPRTADEQFSDRIKNMEQRMTGRGGLGGDKKPKDLMRAIGKIDSNDWNVREIEKKIELSKKTEIHGPKGREKVPKWSKEQFQARQHKMSKPQRQDSREAEKFKDIDQTIRNLDKQLKEGHN------LDVGERGRNKVASIAGQFGKKDEANSDEKNAGSSNATTNTNNTVIPKSSSKVALAFKKQAASEKCRFCKQTVYLMEKTTVEGLVLHRNCLKCHHCHTNLRLGGYAFDRDDPQGRFYCTQHFRLPPKPLPQRTNKARKSAAAQPASPAVPPTAGSVPTAAATSEHMDTTPPRDQVDLLETSRANASADAMSDDEANVIDEHEWSGRNFLPESNNDSQSELSSSDESDTESDSEMFEEADDSPFGAQTLQLASDWIGKQYCEDSDDSDDFYDSSEGIADDGKDDTEGEEFKKARELRRQEVRLQPLPANLPTDTETEKLKLNVDNKENMADRSSLKSGNSFESARSQPSTPLSTPTRVEMEQLERNAPRKFSSEIEAISEKLYHMNNMVKMNKDLEVLAKENLVKSDILRKLTLKEKWLAENAAIAAGQKVTPTPSATAPGLQPKSKFDEKFEKVVSPPQPVVEPKPKPVIDFNLDELKPRKPNFEERPKEQLPRPESLKKPPQQKPKGSSTNVSRSNSLKSNASNGSPKVKKAPISNNSKMQIEGILGTLRKIQSQNSSDQDEDMDVDEDVERKPNKELNSKLKEIQASSFAGTMDHIKSQLTMPTVSAQAPPSMDLSKYFPNQKQEKSSTSSTNKNQVTLKDVNLAKYFPSSPAPQRRTVETVADRLKKSQTEAALAKTKLLEDQANNQAEKTKKEVEKEGESKKITKKVADSKAVPPKRQASLDTFSLREHQMDGALDLTKKKGPTKASAGVKKPAKSGSTTSVTKATATSKGKTIKIVKKIVPKGTKAKKAAEAAQESAVVEAPPEKKPPKDEAERILDEILGDGEYRSPSSEYQRLFQDEKSPSDLSDNIDRILEESGLDVELGLPKRSSKKLVKTKSLGEGDFDMKPSKERLTGVQNILKRFESMSSVTSQNSDEQAAFKLRRMESTTSNLSSLTRSRESLVSVSDSMSDLEKTMDYLRNEWRNEATNFLQKKRDKFYAKKEEQEKESKILAKPDPLDNLPVQYRDSKLAKFFGLAASKSPENRKSPIKKKKSPSKTPKVTKANNSLEELAKISNVRQTKKAQPKTLKPVEVKPLKPASPVPDDFEILDLLEKATEAKELERSKTKSPAVESISQTPKEAIVEISLPVEDIKNLPKTGCDKSSNSSRRGSQSSLIMSRRHSEISLNEKLNQDALAALNQIEKEREAEQVDELFQSMVEEMEQEPQPTAIVEPPEEDIDADSLCTTISKSPSAQPVTVVKRGSSEDQSIEKLFSHFSDEMLVNVEFDSNDELVGITPRATLVSRNTEDRDYLDKLESLERDEETFQPVVGEKFIQENVQDEVDGLHFPSRPQRRPKSSSSSSEPSLPVAPQRLKKKLSKLDPEDMPPSVQDLLQQVYQKNIQPELVEVIPVEGKQTLRFPSMLAEEDVDEVDHSKEGIKKIETAPEEVRKVTEPEDVARVIPSPIKPSISQSNSLKSENSSGSSLVEIPKIITPPKSSSKENSSDWDMEKLPASPMPRRRLLPNQTPYKAPSVASKESSLEWDMEKLPNSPMLPRRNKMRAISPSTNPVQLLNNLPSDVDDEAAQRRLIEDFEQERRQALIKRDENFEAIAAEQRRRDSLQSSSNSSSKRSLPPPTPPMMASRRGTTQDTNRTQDTASRHEGTPPMFKKLDVDGSGTSMDSTSCSTRRSSFAFIELQDNKPVIVPMPKKLKLPKPEPPRFVPEPVATDEPVPEVFQGRAWPKTQLEGEVDLGDSDNEDETEKLKKQLPEYARSDSPPSAAFKNRKWPDGKTVFDKRAESLEEEDIFEGLLSPRKRGSQRFMDKPRSQSPQPFKPLANSSRKSSKSFSDLKKGPSLQSLSAQSSQDTDTLSTTTTVATARPASYANYEDPMDASTQALLDRSKRLHNRKRDFVNERVVERNPYMRDVLRSTDRRDYDDVDEDLTSYRPRHYASSTLNRFPNTTIRKSNNYDYLSPSSDYLSRRSYIPSASATSSYYPSTTRSSHLSDLFRRRSPASGTVSALSGYGNKESCIGLALDRVGHLIESKCTWVRSTKVQTESESTSPDEVELNSATEISTDSEFDNDEIIRQAPKIFIDDTHLRKPTKVQIKSTMIGPNAASAGLHQKQLAAREKGGSYLQKYQPQPPLPQFKPLVQVDPTLLIGSQRAPLQNPRPGDYLLNKTASTEGIASKKSLELKKRYLLGEPANGNKIQKSGSTSVLDSRIRSFQSNISECQKLLNPSSDISAGMRTFLDRTKLGEGSQTTPGQTNELIRSATSNVINDLRVELRIQKTGSSHSTDNEKENVFVNCKNELNKGMEYTDAVNATLLDQLARKSSPTTPTNKTVVEVIDLVTPEKPIDIIDLTALETPKKQLVDGSAMDVDERLTPDSNKISELQQEVKEEPKPDVSRDVKECIPDILGHIKEGTGSKEPGGEDQQSLLEQSDEEKRDSPEKDVAEHELYEPDSVQIQVPNIPWEKSKPEVMSTTGSSGSICSSSDSSSIEDIQHYILESTTSPDTQTVGGKHNVPRLEVHDTSGALMQVDSLMIVNGKYIGDPEDVKFLDMPANVIVPPAPALKTNELDMEDDQEAEAEPVTATPEPVECTVIEAERRVTAPPPLPEMGPPKLKFDSKNENKIESLKNLPLIVESNVEHSQAVKPITLNLSNLARTPDTPTTPTAHDSDKTPTGEILSRGSDSETEHTGTGQVLTETELSDWTADDCISENFVDLEFALNSNKGTIKRRKDRRRSGASKLPSGNEVIHELARQAPVVQMDGILSAIDIDDIEFMDTGSEGSCAEAYSATNTALIQNRGYMEYIEAEPKKTTRKAAPPSSYPGNLPPLMTKRDEKLGVDYIEQGAYIMHDDAKTPVNEVAPAMTQSLTDSITLNELDDDSMIISQTQPTTTEESEALTVVTSPLDTSSPRVLDQFASMLAAGKGDSTPSSSEQQPKTSTVTSSSTGPNSSTTGNVSKEPQEEDLQIQFEYVRALQQRISQISTQRRKSSKGEAPNLQLNSSAPVIESAEDPAKPAEEPLVSMRPRTTSISGKVPEIPTLSSKLEEITKERTKQKDLIHDLVMDKLQSKKQLNAEKRLHRSRQRSLLTSGYASGSSLSPTPKLAAACSPQDSNCSSQAHYHASTAEEAPKPPAERPLQKSATSTYVSPYRTVQAPTRSADLYKPRPFSEHIDSNALAGYKLGKTASFNGGKLGDFAKPIAPARVNRGGGVATADIANISASTENLRSEARARARLKSNTELGLSPEEKMQLIRSRLHYDQNRSLKPKQLEEMPSGDLAARARKMSASKSVNDLAYMVGQQQQQQVEKDAVLQAKAADFTSDPNLASGGQEKAGKTKSGRRPKDPERRKSLIQSLSSFFQKGSGSAASSSKEQGGAVAAVHSEQSERPGTSSSGTPTISDAAGGGGGGGGVFSRFRISPKSKEKSKSCFDLRNFGFGDKDMLVCNAASPAGATSASQKNHSQEYLNTTNNSRYRKQTNTAKPKPESFSSSSPQLYIHKPHHLAAAHPSALDDQTPPPIPPLPLNYQRSDDESYANETREHKKQRAISKASRQAELKRLRIAQEIQREQEEIEVQLKDLEARGVLIEKALRGEAQNIENLDATKDNDEKLLKELLEIWRNITALKKRDEELTIRQQELQLEYRHAQLKEELNLRLSCNKLDKSSADVAAEGAILNEMLEIVAKRAALRPTASQLDLTAAGSASTSAEATGIKLTGQPHDHEESII", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *. .:..:*: : *: : * .. : : * * .** **:.: ***:*** *:* *.:*: * :* :* . : *::*.********** *******:**** ::*********:.* *** *************:********** :*:*:**:****.* .*.* : **. * **** . *:**.::.::***::****:** *: ****************** *::: ***************** **::* :************* **********:**:*****:.* *. ** . **: : * ******:::*:**:*.*::*:** .:*********.*:*:* :. : * . :: .************ *:*******:::*:*: :* * : .* :**:***:**** ****:.: :::. **:**.******* ..*.. **:: : . . : . *:..:: * ** * . * ..*: : .:.: : : .* .***:*: :**:**:: : :: . .. :*:* * ::*: * . :.*: . * :. **.:: :**** .. . . . . . .* .: : : . : .:*:. : : . . . . . : . *: . : . . . . . .: : : : : * : . . * * . : . .. . . : : : . : : :: **:..* .* ..: . . : : . *.. . . . : . :* : . : . * :. .. : : : * . * : ::.. :: . : . * *. . .* .* .* . . . :: :: . .: : : . : * * * . * . .. . .. ::.:. : : .: . : : : . . : :.: : : . . : :. : : . . :::: : :: : : : : : .: : : ::::: : : : : . : : . ", "identical_positions": 321, "similar_positions": 357, "identity": "6.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110110-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AC58H5X5-1", "uniprot_id": "A0AC58H5X5_DANRE", "id": "A0AC58H5X5-1", "name": "", "aln": "MFAVFSSDYITAHSETVALDTFLEIMYYVARVCPVTQHKLADLEHREKLTTMTVFDSDQERFRKAGWGCFRTPLFLVSLVTPPDTDTHSLAMAASETSSTVPESPEPEPCDTTQAELNQDEEDEEDEASEAQQQEPSDPDSVEERFRIDRKKLEIMLYAPTEASGLSGEE-FFEKVMRETNTQVKWPSKLKIGAKSKKDPHVKVEGKRANVLEAKRKILELLETKVNKVTLKMDVTHTEHSHVIGKGGGNIKKVMEETSCHIHFPDSNRSNSSGEKSNQVSIAGPVEGVESARKQIRDLQPLVLTFDLPVTLAGGVVADTSSPVIQHVAQAFGVTVSFRTQPKLYCSTCSVRGVTANTAALKKAICVLMELLLGSGVNGVMVSTQLDVTSQQHLFLLGQNGANFLTVMHQTHTQIILPDLS----SPQHTPSLLIQGTADGVCLARQQLMDCLPVCLMFDLKDEGESDPRRFTQMMQNLGVFISVKPK--VKQTAKSVVVKGLERNIVNVYEARRLLLGLDSTEVSVSTKSVCEVSVMSKHSVDPLLANNGITGYWLN-----VLMQQLRLTDTGSVSIPDAVIGSLSGKPRPTPPPPPGLAVSSEDGRIGLKGVESKLEKILENEDQQTQAESETCSMSHSEVTDVREVIVKPTPSSRRGSQSESSREFNQPITSERLVRADVESVYLNRDRRCSLRIFPSMDINNEDHEYERKKLLANQAMQQKPVVTEVRTPTDTWSGLGFSKSMPTDAVKELRAVSRRCYRPYNNSNNNNNNNHHSQQQQQSWSGKEHGWTGSDSENWRERRGSASSSPPPS--------------SSSYSLSASRSSDVFLTEGGATVSRHLIGRSPS--PAHADDLIELLAQLGLEKYIDIFQQQEIDYQTFLTLSDEDLKEVGVSTFGARRKMLLAIADLSKKRKIPEAFVVKSGYLEGGASGRLPRIMDEDVAAKSNRW", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24009-1", "uniprot_id": "BICC_DROME", "id": "Q24009-1", "name": "Protein bicaudal C", "aln": "---------------MLSCASFNKLMYPSAADVAKPPMVGLEVEAGS---------------------------------------IGSLSSLHALPSTTSVGSGAPSETQSEISSVDSDWSDIRAIAMKLGVQNPDD--LHTERFKVDRQKLEQLIKAESSIEGMNGAEYFFHDIMNTTDTYVSWPCRLKIGAKSKKDPHVRIVGKVDQVQRAKERILSSLDSRGTRVIMKMDVSYTDHSYIIGRGGNNIKRIMDDTHTHIHFPDSNRSNPT-EKSNQVSLCGSLEGVERARALVRLSTPLLISFEMPVMGPNKPQPDHETPYIKMIETKFNVQVIFSTRPKLHTSLVLVKGSEKESAQVRDATQLLINFACESIASQILVNVQMEISPQHHEIVKGKNNVNLLSIMERTQTKIIFPDLSDMNVKPLKKSQVTISGRIDDVYLARQQLLGNLPVALIFDFPDN-HNDASEIMSLNTKYGVYITLRQK--QRQSTLAIVVKGVEKFIDKIYEARQEILRLATPFVKPEIPDYYFMPKDKDLNLAYRTQLTALLAGYVDSPKTPSLLPPSLAGQLTPYANNNHLLLNANGLATPTGVCAPTQKYMQLHNSFQQAQNRSMVAGGQSNNGNYLQVPGAVAPPLKPPTVSPRNSCSQNTSGYQSFSSSTTSLEQSYPPYAQLPGTVSSTSSSTAGSQNRAHYSPDSTYGSEGGGVGGGGGGGARLGRRLSDGVLLGLSNSNGGGGNSGGAHLLPGSAESYRSLHYDLGGNKHSGHRAFDFDMKRALGYKAMERTPVAGELRTPTTAWMGMGLSSTSPAPAPLENGENGAAGGGASSGWRLPPGLGSPYGLSATTGLLDATPVNRRMQ--LAKHKDIQTLLTSLGLEHYIKIFVLNEIDLEVFTTLTEENLMELGIAAFGARKKLLTAIHTLLANEAACSTMPSSSSSQNSSSPRFSGSAAPGAERRPSNQW", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q07834-1", "uniprot_id": "YL032_YEAST", "id": "Q07834-1", "name": "KH domain-containing protein YLL032C", "aln": "------------------MDNFKIYSTVITTAFLQVPHLYTTNRLWK-----------------------------------------PIEAPFLVEFLQKRISSKELKNTKAICHIDPSWVNLNASFIRDD--------MISIKATTDDMDLDAICRISLPLP--MNTNDLTAELEKMKRILLDLSEKFNLELIITKEPAYFTP---EQTGESKELCIYVHALGFRSNLMECEPQLLAFVDLIKKNGMTLP-----PQHYIIEPMELNSYSVLPLYMGVDMENFKHISRAFKTSIYAPSLITLSRDLKAN-----------PQIFFSGAVHSLSLLARKTLRESISVNSKSFFYRRLTNITPGKLLFIRKYYQQKVNQLILKYQSLIRVTNEYIEFQSISTNLLEMVIKNFTIQVLHEIV-------------------EVQISLNENCAMSPELIIDSFFGHTGNQIVVITPKEDSFNQLIVVGNQSSTDEASDTSILHYLSDFIMGSNQVINPNLRQIKAIFEIHPDFEDFISGKKNGKLTRIMELSACLIQLEMEEEDDNLYLNLVSDSFPDFKES--FKNVINEFPAEESFFIPEVCHRPIIG-----TGGSLIQATMRKHNVFIQFSNSFNLPQNKISMIRYDNVIIRCPRKNKANICLAKNDLKQIVQEYDSLQSKTLIRFSSGQYRHILHVN------------GQKNIIGQIEKNENVYIMIPLKEPLDGTSQLSIQGNDENASRAANELVNSAFGYEYEFKIDQEIDPNKEYEFYNLIVVPFLQIMNIIVTFEKDLITFTFEKDTN--------------ENTLTKAIELLSNYLETQKTKIIFKKIIKKFVLGSASSKSNTSNSNTNGNFRSMNNAKSRTTIDNTSQSGASPQRHKMPVITTVGGAQAIKGYIPNTYYNGYGYGYGYTYEYDYNYANSNKAQTNNRHKYQNGRK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* : . . .: * . . :: . : . . : * .*: : . : : .: . . :. . :::: .*:* :. .:*. : :: : . :* :.* .: . :* * . .* . *.: . . . : : : :: :: . * * ..: : . : * . : : . :::. . .. :::. * : :. : . ..*:* :: :. * :: :: * :: :: * :: .: .. .: : . . * : : ::: : ::: :. * :. . * .. .. :. .. .: .. * . . . . * . * : :.. * . : : . . . . :. : . . . . .. . . : . . . .: . . : . : : : : . : . . .. . * : : : : : .: :. .:. . ** : : :::.*. : : * : . : . . : ", "identical_positions": 34, "similar_positions": 221, "identity": "3.52%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110114-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6VVX0-1", "uniprot_id": "CP2R1_HUMAN", "id": "Q6VVX0-1", "name": "Vitamin D 25-hydroxylase", "aln": "MWKLWRA--------EEGAAALGGALFLLLFALGVRQLLKQRRPMGFPPGPPGLPFIGNIYSLAASSELPHVYMRKQSQVYGEIFSLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHRRLAVNSFRYFGYGQKSFESKILEETKFFNDAIETYKGRPFDFKQLITNAVSNITNLIIFGERFTYEDTDFQHMIELFSENVELAASASVFLYNAFPWIGILPFGKHQQLFRNAAVVYDFLSRLIEKASVNRKPQLPQHFVDAYLDEMDQGKNDPSSTFSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHFPHELVPDLKPRLGMTLQPQPYLICAERR--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6VVW9-1", "uniprot_id": "CP2R1_MOUSE", "id": "Q6VVW9-1", "name": "Vitamin D 25-hydroxylase", "aln": "MLELPGA--------RACAGALAGALLLLLFVLVVRQLLRQRRPAGFPPGPPRLPFVGNICSLALSADLPHVYMRKQSRVYGEIFSLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWIDHRRLAVNSFHYFGSGQKSFESKILEETWSLIDAIETYKGGPFDLKQLITNAVSNITNLILFGERFTYEDTDFQHMIELFSENVELAASAPVFLYNAFPWIGILPFGKHQRLFRNADVVYDFLSRLIEKAAVNRKPHLPHHFVDAYLDEMDQGQNDPLSTFSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVHKEIDLIVGHNRRPSWEYKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWKDPDMFYPERFLDSNGYFTKKEALIPFSLGRRHCLGEQLARMEMFLFFTSLLQQFHLHFPHELVPNLKPRLGMTLQPQPYLICAERR--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F6P2A1-1", "uniprot_id": "F6P2A1_DANRE", "id": "F6P2A1-1", "name": "Vitamin D 25-hydroxylase", "aln": "MISIKRLTSPLSLSWEQTLICLLGLFTTLLILLVIRQLVKQRRPRGFPPGPTPLPIIGNMLSLAT---EPHVYMKRQSDIHGQIFSLDLGGIPTVILNGYDAIKECLYHQSEVFADRPSLPLFQKMTKMGGLLNCKYGRGWIEHHKLAVNCFRYFGTGQRMFER-ISEECLYFLDAIDQHQGKPFNPKHLVTNAVSNITNLIIFGQRFTYDDGDFQHMIEIFSENVELAASSWAFLYNAFPWMEYLPFGKHQRLFRNANEVYKFLLQIIRRFSQGRVPQSPQHYIDAYLDEMEQSTPDKATSFSQDNLIFSVGELIIAGTETTTNCLRWAMLYMALYPRIQEKVQMEIDSVLN-GRQPAFEDRQRMPYVEAVLHEVLRLCNIVPLGIFRATSQDAVVRGYTIPKGTMVITNLYSVHFDEKYWSDPSIFCPERFLDCNGKFIRHEAFLPFSIGKRHCLGEQLARLEMFLFFTTLLQRFHLQFSEGFIPSLSAKLGMTLQPQPYSICAIRRQQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .: . .* * : **: * :***::**** ******. **::**: *** *****::** ::*:*********.**:*****.:**** ****:*****.**** **********.:*****::*::****.*:*** **: ** * ** : ***: ::* **: *:*:***********:**:****:* *******:**********: .********: *******:***** **.** ::*.: : .* *: *:*::*******:*. * ::**::******************* ****:*:*****.** :*: *** ::. . :*::: : :***.*********:*********:***:*******:***** *************** **.:* ******..* * ::**::***:*:******:***:*******:***:***:*.. ::*.*..:********** *** ** ", "identical_positions": 325, "similar_positions": 108, "identity": "63.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110114-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9V399-1", "uniprot_id": "CP303_DROME", "id": "Q9V399-1", "name": "Probable cytochrome P450 303a1", "aln": "---------MFYTVIWIFCATLLAILFGGVRK---PKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYGFYGLKIGKDKVVIAYTNDAISEMMTN--EDIDGRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYE-PGSPEITQLLETFFELFKNIDMVGALFSHFPLLRFIAPNFSG-YNGFVESHRSLYTFMSKEIELHR--LTYKNYDEPRDLMDSYLRAQDE--GNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRD--RTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFDG-HLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQ-VPEEVPLEGATAAVKPYDIMLVAREQ--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VW43-1", "uniprot_id": "CP305_DROME", "id": "Q9VW43-1", "name": "Probable cytochrome P450 305a1", "aln": "-------MSALIFLCAILIGFVIYSLISSARR---PKNFPPGPRFVPWLGNTLQFRKEASAVGGQHILFERWAKDFRS--DLVGLKLGREYVVVALGHEMVKEVQLQ--EVFEGRPDNFFLRLRTMGTRKGITCTDGQLWYEHRHFAMKQMRNVGYGRSQMEHHIELEAEELLGQLERTEEQP------IEPVTWLAQSVLNVLWCLIAGKRIARQEDGTLRRLLDLMNRRSKLFDICGGLLAQFPWLRHVAPDRTG-YNLIQQLNTELYGFFMDTIEEHRRQLAKDPSPAESDLIYAYLQEMKDRSAGGESSTFNETQLVMTILDFFIAGSQTTSNTINLALMVLAMRPDVQEKLFSQVTASVAAASTDAFPHLSRREAFDYMDAFIMEVQRFFHITPITGPRRALWATKLGGYDIPKNATILISLRSVHLDKEHWKDPLEFRPERFIDSAGKCFKDEYFMPFGMGRRRCLGDALARACIFSFLVRIVQHFSVVLPAGE-SPSMVLLPGITLTPKPYKVQFVKRT---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0AB32TDH5-1", "uniprot_id": "A0AB32TDH5_DANRE", "id": "A0AB32TDH5-1", "name": "", "aln": "MLVGLLKLDLSSVGLSLFLGLFCLALFEICRIRIYKGRYPPGPTPLPFVGTIPHFLKNPMG----------FIRSLSQYGEMTTVYLGRKPAIILNALQLMKEAFVQNGSSFSGRPPVPVLTWVNQG-YGIIMAMDGHSWRQQRRFALHTLRNFGLGKKSVEERVTEESGYLICELLRVEGKP------FNPQHAIHNAAANIICSIVFGDRFD-YDNKSFTYLLEIIKEN---LDLAGSFAGQMVNLVPIIKNLPGPHQKIYQNGEEFKSFIRESVKAHRETLDPD---SPRDFIDAYLLEMEKQ-KSTQDSTFHEDNMVMSVGDLFFAGTDTTATTIRWGLLYLTQNPDVQERCHDEIVQVLGFDRFPIMDDR---DQLPYTLATVHEIQRCANVAPSGVPHQTTKPIKLRGYDIPQGTQILINLMGILANKEHWKHPDTFNPENFLDDKGHFFKPEAFLPFSLGPRACLGETLAKTELFLFVTSLLQRIRFSWPTGEKWPDMNRILSVIRSPEPFNIICNSRDSEH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . . *: * .:**** * :*. :. : : :. . : : :*:. .:: : :.* : . :.*** . . . : **. * ::*:* :: ::*.* .:. : . : *: *: :* :. :: . * : .:: * * . : **: : . :*: *.: .:: * : : .* :: : : .: *: . :: ** * . *:: :** .. . :.. * : .:: *:*:**::** .:: :: *. .*::**: ..:: :. : * * * * : . *::: :* **:**:.: :: : .: : .: .* *.*:.:: . : * * **.:* : *:*: *.: :* * . ::*.: . .*: *. : . : :*:.: * ", "identical_positions": 78, "similar_positions": 172, "identity": "14.74%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110119-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N3F8-1", "uniprot_id": "MILK1_HUMAN", "id": "Q8N3F8-1", "name": "MICAL-like protein 1", "aln": "MAGPRGALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVFENNRLAFEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCSPGQAGVSPPRKGLAPCSP-PSVAPTPVEPEDVAQGEELSSGSLSEQGTGQTPSSTCAACQQHVHLVQRYLADGRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEHCARLGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQIPTKPRVPGKL----------------QE------------------LASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRGTPKPSEGTPAPR-KDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLESKPYNPFE-EEEEDKEEEAP-AAPSLATSPALGHP--------------ESTPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLALHASRLSHSEPPSATPSPALSVESLSSESASQTAG----AELLEPPAVPKSSSEPAVHAPGTP---GNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSGATPTPLLLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVRPPAPGHGFPLIKRKVQADQYIPEEDIHGEMDTIERRLDALEHRGVLLEEKLRGGLNEGREDDMLVDWFKLIHEKHLLVRRESELIYVFKQQNLEQRQADVEYELRCLLNKPEKDWTEEDRAREKVLMQELVTLIEQRNAIINCLDEDRQREEEEDKMLEAMIKKKEFQREAEPEGKKKGKFKTMKMLKLLGNKRD-AKSKSPRDKS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BGT6-1", "uniprot_id": "MILK1_MOUSE", "id": "Q8BGT6-1", "name": "MICAL-like protein 1", "aln": "MAGPRGALLAWCRRQCEGYRGVDIRDLSSSFRDGLAFCAILHRHRPDLLDFQSLSKENVFENNRLAFEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFTSSGQAAASPPKPGKDPAPPSPTSTSPAVQPGEEAQGDDLSPDSLSEQGKQQPPSSACAACGQRVHLVQRYLAEGRLYHRHCFRCRQCSSTLVPGSYSSGPEEGTFVCAERCTRLGPGSRSGTR-----LLSQQRQQPAAAEAKDAEDNDPSLSVAAVAEADRLQASSEVQFHTPTKPPLPSKP----------------QE------------------LASPPGGRPTPAPRKASESSALTPPTPRPRSSLQQDGTVEQSVSSGLVNGRLQEPPVPKPRGTPKLSERMAAPR-KDPPWITLVQTEPKKKPAPQPPSSGPGPLSQAYRQVEDGGLEEQTQKSSGTEPEPKPYNPFE-EEEEEEGEPAP-PVPSPSLAPPVPSPSPAPPVPSPAPAPSEATPKSLHPWYGITPTSSPKTKKRPAPRAPSASPLAIHASRLSHSEPPSATPSPALSVESLSSESSSHTAN----AEPLEPPAVPKSSSDPAVHVPGTPGTSGNSVTPSANSSLSSSGELGQPSGEQMLQA------RTKGSAGTHSTKPFSGATPTPFLLAGDRNPAPPVGSASPQLQIKSSCKENPFNRKPSPSASPTVRKATKGAKPVRPPAPGHGFPLIKRKVQADQYIPEEDIYGEMDNIERQLDALEHSGVLLEEKLRGGANEGSEDDMLVDWFKLIHEKHLLVRRESELIYVFKQQNLEQRQADVEFELRCLLNKPEKDWTDEDRAREKVLMQELMTLIEQRDAIVNCLDEDRQREEEEDKMLETMIKKKDFQREAESDSKKKGKFKTIKVLKFLGNKRE-AKSKAPGDKS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B5P6-1", "uniprot_id": "A0ACD6B5P6_DANRE", "id": "A0ACD6B5P6-1", "name": "", "aln": "-MGSLKALQDWCRNQCESYNNVDITNMTSSFRDGLAFCAIIHRHRPDLIDFDSLSKENVFENNRLAFEVAERELGIPALLDAEDMVSMSVPDRLSIITYVSQYYNFFTNKSHTVSKCIKSPSSSGYIRSAIKRPLASPED---RDAHNESGADIQPKRSTLSSTCSVCGKHVHLVQRILVDGKLYHRNCFRCRECSRTLLPGSYKFTEDPGALVCTHHFTRSASTNQNGHS------DMSNRLAKLTTSAEDPLCGNDSEISPQRDEEKTSELEERLRKQTDSKSKVETEEGANPFDESEEEDRDIQQEDLKSATDVANGDTPSTSVKSTAAESRPVPAPRRVLEPSPAPRPVPRLRRSRISESITVNGDPD---QTQTPQVPVPKERMHSPARKAGDTPKPKDPPWLALVQSETKRKPAPRPPTGTAVPPSTG---ASPSRKEETSRPS-------TPPNPFENEEEEEESELGPEDVPGPVVASHPWYG------ITHSTEVPGGDAGKQSPARSESPIS-IRRKKRPAPKAPNSS-----TSAFPSSQTSSPASSLALSTESLSSSSSDYSAVPQKAAANEQDHLFTKSVSEPSINTPASA------LSQKAELQPRCSPNLSPPPPP-----------PTNTSSAPATPQTNRSARP-PSLSAG---LKITPTSQTPGTPGKRTCKENPFNRKTTTSASSFVSRPPKGPRPARPPAPGHGFPLIKRKVQSDQFIPVEDIHVEMSDLEKRLDELEHRGVDLEKSLRECSNDEEEEHLLVDWFTLIHEKHLLVRREAELVYTAKQQNLEERQADVEYELRCLLNKPEKEWTSEDKDREKQLMADLVTIIEQRNQIVNNIDIDRQREEEEDKLVAAMLKKKDFHGQGE-QKKKSGKFKPMKVLKRLSTKNEGVKDNSPRKENS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. ** ***.***.*..*:* :::************:*******:**:****:**************:*********.:********* ***:********.* . .:: . : . .: . ..* : : . .. . * . .. **:*:.* ::****** *.:*:****:*****.** **:**:*. : *::**:.: :* .. .:.* .:: : .*:* .. * . * . : . . : : :*. : : ** ::.. .**.****:. *.:. . *.** * * .:. . :. .. : : : **** * . : :*: *****::***:*.*:**** **:. . * * .. . ** :: * .* **** ****:: * .* .*. :. . . . * . :* * : ******:**.:* :* :. *:..*.:.* ***.*****.*:. :* * : ..** *:*:::.*.:. :: .:: . .* :* * *. *:.. ..:. .* * * * .* . * :* * :*********.:.:**. . :..**.:*.*****************:**:** ***: **. :*::** *** ** **:.** *: *:.:*****.************:**:*. ******:******:***********:**.**: *** ** :*:*:****: *:* :* **********:: :*:***:*: :.* : **.****.:*:** *..*.: .*.::* .:. ", "identical_positions": 363, "similar_positions": 251, "identity": "39.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110125-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6R6I6-1", "uniprot_id": "RXFP1_RAT", "id": "Q6R6I6-1", "name": "Relaxin receptor 1", "aln": "-----MTSGPFFFCVFIIGRYFTLGNAQ---------------------------------------------------------DVSCPLGSFPCGNISKCLPQLLHCNGVDDCGNQADED--NCGDNNGWSLQLDKYFANYYKLTSTNSIEAET---------------------SECLVGSVPMHCLCRD--LELDCDEANLRAVPSVSSNVTVMSLQWNFIRTLPPNSFRKYHDLQKLCLQNNKIRSVSVSAFRGLHS--LTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPLTFYGLNSLILLVLMNNALTRLPDKPLCQHMPRLHWLDFEGNRIHNLRNLTFIS-CNNLTVLVMRKNKINHLNEHAFTHLQKLDELDLGSNKIENLPPNIFKDLKELSQLNISYNPIQKIEVNQFDYLAKLKSLSLEGIEISNIQQRMFRPLINLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVFVWVVSAITCFGNIFVICMRPYIRS-ENKLHAMSIMSLCCADCLMGVYLFVIGAFDLKFRGEYRKHAQPWMESVHCQFMGSLAVLSTEVSVLLLTFLTLEKYICIVYPFR-CLRPRKCRTVAVLIFIWITGFIVAFAPLGNK--EFFKNYYGTNGVCFPLHSEDTGSTGAQIYSVVIFLGINLVAFIIIVFSYGSMFYSVHQSTITATEIQKQVKKEMILAKRFFFIVFTDALCWIPIFILKFLSLIRVEIPDTITSWVVIFILPINSALNPIIYTLTTRPFKEMIHQLWYNYRQRRSVDRKGTQKAYTPSFIWVEMWPLQEMS-TEFMKPDAFTDPCDLSLVSRSSRLNSYS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6R6I7-1", "uniprot_id": "RXFP1_MOUSE", "id": "Q6R6I7-1", "name": "Relaxin receptor 1", "aln": "-----MTSGPFFFCIFIIGKYFTLGSAQ---------------------------------------------------------DVSCPLGSFPCGNMSRCLPQLLHCNGVDDCGNRADED--HCGDNNGWSLQLDKYFANYYKLASTNSFEAET---------------------SECLVGSVPMHCLCRD--LELDCDEANLRAVPSVSSNVTVMSLQRNFIRTLPPNGFRKYHELQKLCLQNNRIHSVSVSAFRGLRS--LTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPLTFYGLNSLILLVLMNNALTRLPDKPLCQHMPRLHWLDFEGNRIHNLRNLTFIS-CNNLTVLVMRKNKINYLNEHAFTHLQKLDELDLGSNKIENLPPNIFKDLKELSQLNISYNPIQKIEVNQFDCLAKLKSLSLEGIEISNIQQRMFRPLINLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVFVWVVSAITCFGNIFVICMRPYIRS-ENKLHAMSIISLCCADCLMGVYLFVIGAFDLKFRGEYNKHAQPWMESVHCQFMGSLAILSTEVSVLLLTFLTLEKYICIVYPFR-CLRPRKCRTITVLIFIWIIGFIVAFAPLGNK--EFFKNYYGTNGVCFPLHSEDTGSTGAQIYSVVIFLGINLVAFIIIVFSYGSMFYSVHQSSVTVTEIQKQVKKEVVLAKRFFFIVFTDALCWIPIFILKFLSLLQVEIPDSITSWVVIFILPINSALNPIIYTLTTRPFKEMIHQLWHNYRQRRSVDRKETQKAYAPSFIWVEMWPLQEMS-SGFMKPGAFTDPCDLSLVSQSSRLNSYS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBX9-1", "uniprot_id": "RXFP1_HUMAN", "id": "Q9HBX9-1", "name": "Relaxin receptor 1", "aln": "-----MTSGSVFFYILIFGKYFSHGGGQ---------------------------------------------------------DVKCSLGYFPCGNITKCLPQLLHCNGVDDCGNQADED--NCGDNNGWSLQFDKYFASYYKMTSQYPFEAET---------------------PECLVGSVPVQCLCQG--LELDCDETNLRAVPSVSSNVTAMSLQWNLIRKLPPDCFKNYHDLQKLYLQNNKITSISIYAFRGLNS--LTKLYLSHNRITFLKPGVFEDLHRLEWLIIEDNHLSRISPPTFYGLNSLILLVLMNNVLTRLPDKPLCQHMPRLHWLDLEGNHIHNLRNLTFIS-CSNLTVLVMRKNKINHLNENTFAPLQKLDELDLGSNKIENLPPLIFKDLKELSQLNLSYNPIQKIQANQFDYLVKLKSLSLEGIEISNIQQRMFRPLMNLSHIYFKKFQYCGYAPHVRSCKPNTDGISSLENLLASIIQRVFVWVVSAVTCFGNIFVICMRPYIRS-ENKLYAMSIISLCCADCLMGIYLFVIGGFDLKFRGEYNKHAQLWMESTHCQLVGSLAILSTEVSVLLLTFLTLEKYICIVYPFR-CVRPGKCRTITVLILIWITGFIVAFIPLSNK--EFFKNYYGTNGVCFPLHSEDTESIGAQIYSVAIFLGINLAAFIIIVFSYGSMFYSVHQSAITATEIRNQVKKEMILAKRFFFIVFTDALCWIPIFVVKFLSLLQVEIPGTITSWVVIFILPINSALNPILYTLTTRPFKEMIHRFWYNYRQRKSMDSKG-QKTYAPSFIWVEMWPLQEMP-PELMKPDLFTYPCEMSLISQSTRLNSYS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58H5G9-1", "uniprot_id": "A0AC58H5G9_DANRE", "id": "A0AC58H5G9-1", "name": "", "aln": "---MQVHIASILMCGASVVLTMFNVSED---------------------------------------------------------QPYCPLGYFPCGNLSTCLPQVLHCNGVDDCGNQADEE--NCGDNNGWPHLFDNYFG-----IPSNNLGNKS---------------------NACLLGTVPAECQCRD--LELDCDGAHFKDVPMVSINVTMMSLQRNGLRKLNADMFLKYQSLQKLYLQHNRIKSVHPQAFRGLYN--LTRLYLSYNRITTLLPDVFQDLHKLEWLILENNSLHHISSLTFSGLRSLVLLVLLNNALTKLDD--ICLEMPRLNWLDIEGNKMETVGNVTFRS-CNMLTVLVLQRNRISRIHAQAFSLLRKLGELDLSSNRIEAIPPDLFVNLGDLLQLNISYNPIMNLRVDHFDKLHKLKSLSIEGIEIGNIHRRMFEPLKNLTHIYFKKFQYCGYAPHVRSCKPNTDGISSFEDLLANIVLRVFVWVVSATTCFGNIFVICMRSYIRS-ENKLHAMCIISLCCADGLMGVYLFMIGAYDLKFRGEYNRHAQAWMDSEACQVIGSLAMLSTEVSVLLLTYLTLEKYICIVYPFR-YLTPGRRRTVTILVVIWVLGFIIAFLPLLFK--GVFRNFYGTNGVCFPLHSEQPETLGAQIYSIVIFLGLNLVAFLIIVLSYGSMFYNIQRTGTQTTKYSNHIKKELTIAKRFFSIVITDSLCWIPIFILKILSLMEVEIPGTISSWVVIFILPINSALNPILYTLTTRPFKETLLQVWSNYRQRRPLFSSR--PPHLPSFTWQEMWPLQENSQTLCSHPSDICNTTHLLPVEASNGELMGC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBP0-1", "uniprot_id": "Q9VBP0_DROME", "id": "Q9VBP0-1", "name": "", "aln": "MVYGRSIAVGFCLMTVVLLLAAVIFYLS---------------------------------------------------------LGPCPAASFACDNGTLCVPRRQMCDSRNDCADSSDENPVECGLLYGSKEIADKIVRNAIEKKQQRLISAVSNASGADSTTSMVPRNQSLTLNMTCDIVTYPKACQCGQGTILYCGRYAKLRRFPRLSSEVTNLIIIRN-NLTLRDNIFANFTRLQKLTLKYNNISRVPLGSFSGLFH--LERLELSHNNVSHLPHGVFLGLHSLQWLFLVNNHLHHLPVEQLRFFRRLEWLVLSRNRLT--LRNVQLPKIPTLYEVYLDFNRIEYIGEETFSQ-LDNLHLLDLQHNLITHIHGRAFANLTNMRDIRLVGNPIKELSGETFLHNTRLEALSLALMPIHISSS--LMEPLNISFLNLTGIRYDHIDFEAINSMRNLTYIIYDRFFYCSMTPRVRMCKPSTDGVSSFQDLLSKPVLRYSAWVMATLTIAGNVLVLWGRFIYRD-ENVAVTMVIRNLALADMLMGFYLVTIGVQDYRYRNEYYKVVLDWITSWQCTLIGTLAVSSSEVSMLILAFMSLERFLLIADPFRGHRSIGNRVMWLALICIWITGVGLAVAPVLLWRTSTLPYYGSYSGTCFPLHIHEAFPMG-WLYSAFVFLGVNLLLLVMIAMLYTALLISIWR----TRSATPLTLLDCEFAVRFFFIVLTDFLCWVPIIVMKIWVFFNYNISDDIYAWLVVFVLPLNSAVNPLLYTFTTPKYRNQIFLRGWKKITSRKRAEAGNGNVATTTTGTATGSSQHPDDFTIFAKAAMRCH-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "X2JJX6-1", "uniprot_id": "X2JJX6_DROME", "id": "X2JJX6-1", "name": "", "aln": "MSIAIMPHLPITFTLAILLAIASNEGAQGVESATRTAIEAIRTGIGTKPETEIADATEAEAPVREVISLLGIIDGAESDILVPDADDKCPGGYFHCNTTAQCVPQRANCDGSVDCDDASDEVN-------CVNEVDAKYWDHLYRKQPFGRHDNLR--------------------IGECLWPNENFSCPCRGDEILCRFQQLTDIPERLPQHDLATLDLTGNNFETIHETFFSELPDVDSLVLKFCSIREIASHAFDRLADNPLRTLYMDDNKLPHLPEHFFPEGNQLSILILARNHLHHLKRSDFLNLQKLQELDLRGNRIGN-FEAEVFARLPNLEVLYLNENHLKRLDPDRFPRTLLNLHTLSLAYNQIEDIAANTFP-FPRLRYLFLAGNRLSHIRDETFCNLSNLQGLHLNENRIEGFDLEAFACLKNLSSLLLTGNRFQTLDSRVLKNLTSLDYIYFSWFHLCSAAMNVRVCDPHGDGISSKLHLLDNQILRGSVWVMASIAVVGNLLVLLGRYFYKSRSNVEHSLYLRHLAASDFLMGIYLTLIACADISFRGEYIKYEETWRHSGVCAFAGFLSTFSCQSSTLLLTLVTWDRLMSVTRPLK-PRDTEKVRIVLRLLLLWGISFGLAAAPLLPN-PYFGSHFYGNNGVCLSLHIHDPYAKG-WEYSALLFILVNTLSLIFILFSYIRMLQAIRDSG--GGMRSTHSGRENVVATRFAIIVTTDCACWLPIIVVKLAALSGCEISPDLYAWLAVLVLPVNSALNPVLYTLTTAAFKQQLRRYCHTLPSCSLVNNETRSQTQTAYESGLSVSLAHLGGGVGGGSGRKRMSHRQMSYL----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . *. . * *.. : *:*: *:. ** : :** : * . * * : . ::: : : * .: * : ::.* *: * : :* * * * :. *.:. * .* : *. *:: * * :: : :. * * * * : .:* * : :: *::. : * * * : * * : .:*. : .: : * .* :. : * . * * : * : ::. * : * . :. . :. : .* :* :. * *. : .** *.* **:** .** . : * .**::: : **::*: * :. .* :: : *. :* ***.** *. * :*.** : * * * . * *: * : * *:*: :: :: : :. *:: . *: :* .. :* *: : . .*.*:.** .:. . * ** :*: :* :::* : * :: : : .* ** ** ** **:**:::*: : :*. : :*:.:::**:***:**::**:** ::: : . . : ", "identical_positions": 134, "similar_positions": 188, "identity": "15.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110125-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F8VPK0-1", "uniprot_id": "SKI3_MOUSE", "id": "F8VPK0-1", "name": "Superkiller complex protein 3", "aln": "-------------------MSSKEVKTALKSARDAIRNKEYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQGAYKKAAELEPEQLLAWQGLASLYEKCNQVNAKDDLPGVYQKLLDLYESADRQKWCDVCKKLVALYHQEKKHLEVARTWHRLIKTRQ-EDGADRQELYELWRKLSQLLAENIEDQNNETQQMLLTAFENALDLADNIPSEDHQVLYRNFIQCLSKFPHETTKLKKACEEMIAIYPTVQYPLEVICLYLIDSGSLTSEGHQYCCKLVEMNSKSGPGLIGLGIIALQDKKYEDAVRHLTEGLKESPVCIAGWCHLAEAQVKMHRPKEAILSCNQALKTIDNFGASGGNLHQKNLCLRLKAEALLKLSDGASSEEAVRTLDQVSDVDNTPGLLVLQGLACLNTGAVDKATKIMEDLVTSYPDLAEAHALEGRVHFTKKDYVQAEVSFQRALEKDAEVAEYHYQLGLTYWFMGEETRKDKTKALTHFLKAARLDAHMGKVFCYLGHYYRDVAGDRNRARGCYRKAFELDDNDAESGAAAVDLSLELEDTETALAILTAVTQKASAGAAKWAWLRRGLYHLKAGQHSQAVADLQAALRADPKDCNCWESLGEAYLSRGGYTTALKSFMKASELNPDSTYSVFKVAAIQQILGRYSEAIAQYQLIIKMKEDYVPALKGLGECHLLLGKVALVDFLDGKAVDYVEQALGYFTRALQHRADVSCLWKLVGDACTCLHPVSPSKVHVHVLGALLGQ--KEGQEVLKKEELLSLGGRCYGRALKLMSTS-NTWCDLGINYYRQVQHLAETGSSMSDLTELLEKSLHCLKKAVRLDSNNHLHWNALGVVACYRGVGNYALAQHCFIKSIQAEQINAAAWTNLGVLYLATENIEQAHEAFKMAQSLDPSYLLCWIGQALIAERVGSYDTMDLFRHTTELSMHTEGAIGYAYWVCTTLQDKSNRETELYQYNILEMNAIPAAQGVLCKYVERIQNSASAFTMLGYLNEHLQLKKEAAEAYQRATTLLHSAEDQNTYNVAVRNWGRLLCSIGDYDRAIQAFKSTPLVELEDIIGFALALFMKGLYKESGSAYERALAVCKSEQDKAHILTAMAIVEYKQGKMDAAKSFLFKCSILKEPTAESLQALCALGLAMRDATLSKAALNELLKHIK-RRN-DYHSCLLMSAIYALQGHSVAVQRQVAKAVHSNPADPALWSLLSRIVAQYTQRSAKGGAVAGNVAHILDLNHGKKALLYTAVNQLAMGSSTAEDKSNTALKTIQKAAFLSPDDPAVWAGLMAACHADDKLALLNNTQPKRVDLYLALRSAVAASLKDKEILQN-YNQSLEKWSFSQVVTGLIDTGKTSEAESLCTQSLKSNPDQPAVILLLRQVQCMSLLESQKP--LPDAVLEELQKTVMSNSTSVPAWQWLAQVYQSQGMMGAAEMCYRKSLQVASQQGNWSGKLSSLLKLALLALEVCMANVSGDHWSSLVQEATSEALKVCFSPLAVFLQALLQFNRKMGARETRRLLERIVYQTGYPSS--IVSAARWYLLRHLYAKDDPELIDVLVRNAETHGDKRILELNRKLSAQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PGP7-1", "uniprot_id": "SKI3_HUMAN", "id": "Q6PGP7-1", "name": "Superkiller complex protein 3", "aln": "-------------------MSSKEVKTALKSARDAIRNKEYKEALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGLANLYEKYNHINAKDDLPGVYQKLLDLYESVDKQKWCDVCKKLVDLYYQEKKHLEVARTWHKLIKTRQ-EQGAENEELHQLWRKLTQFLAESTEDQNNETQQLLFTAFENALGLSDKIPSEDHQVLYRHFIQSLSKFPHESARLKKACEGMINIYPTVQYPLEVLCLHLIESGNLTDEGQQYCCRLVEMDSKSGPGLIGLGIKALQDKKYEDAVRNLTEGLKESPVCTSGWYHLAEAQVKMHRPKEAVLSCSQALKIVDNLGASGNSLYQRNLCLHLKAEALIKLSDYDSSEEAIRTLDQISDADNIPGLLVLKSLAYRNKGSFDEAAKIMEDLLSSYPDLAEVHALEALIHFTKKDYLQAEKCFQRALEKDTEVAEYHYQLGLTYWFMGEETRKDKTKALTHFLKAARLDTYMGKVFCYLGHYYRDVVGDKNRARGCYRKAFELDDTDAESGAAAVDLSVELEDMEMALAILTTVTQKASAGTAKWAWLRRGLYYLKAGQHSQAVADLQAALRADPKDFNCWESLGEAYLSRGGYTTALKSFTKASELNPESIYSVFKVAAIQQILGKYKEAVAQYQMIIKKKEDYVPALKGLGECHLMMAKAALVDYLDGKAVDYIEKALEYFTCALQHRADVSCLWKLAGDACTCLYAVAPSKVNVHVLGVLLGQ--KEGKQVLKKNELLHLGGRCYGRALKLMSTS-NTWCDLGINYYRQAQHLAETGSNMNDLKELLEKSLHCLKKAVRLDSNNHLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGVLYLTNENIEQAHEAFKMAQSLDPSYLMCWIGQALIAEAVGSYDTMDLFRHTTELNMHTEGALGYAYWVCTTLQDKSNRETELYQYNILQMNAIPAAQVILNKYVERIQNYAPAFTMLGYLNEHLQLKKEAANAYQRAILLLQTAEDQDTYNVAIRNYGRLLCSTGEYDKAIQAFKSTPLEVLEDIIGFALALFMKGLYKESSKAYERALSIVESEQDKAHILTALAITEYKQGKTDVAKTLLFKCSILKEPTTESLQALCALGLAMQDATLSKAALNELLKHIK-HKDSNYQRCLLTSAIYALQGRSVAVQKQISKAVHSNPGDPALWSLLSRVVAQYAQRNAKGGVVAGNVAHILDSNHGKKALLYTAVNQLAMGSSSAEDEKNTALKTIQKAALLSPGDPAIWAGLMAACHADDKLALVNNTQPKRIDLYLALLSAVSASIKDEKFFEN-YNQSLEKWSLSQAVTGLIDTGRISEAETLCTKNLKSNPDQPAVILLLRQVQCKPLLESQKP--LPDAVLEELQKTVMSNSTSVPAWQWLAHVYQSQGMMRAAEMCYRKSLQLASQRGSWSGKLSSLLRLALLALKVCMANISNDHWPSLVQEATTEALKLCFCPLAVLLQALLQFKRKMGARETRRLLERVVYQPGYPKS--IASTARWYLLRHLYAKDDYELIDVLVNNAKTHGDTRALELNQRLSSQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F2R1-1", "uniprot_id": "E7F2R1_DANRE", "id": "E7F2R1-1", "name": "", "aln": "MRQILLAEWKATKFGLQRIMSSKEVKAELKNAREAIKNKEFKEALKHCKAVLKLEKNNYNAWVFIGVAATELQQPDQAQTAYRKASELEPEQLLAWQGLANLYEKSDQADFKAELPKIYQKLITLYETSDKAKCFEVTKKLVEIYQSEKNYLQVARVWRRLIQVKEDEEGLEDAELLELWKEMTRLLQDTVDDQDNETQQHLISAFERALQMTVDVPSEAHRSLSQDYIKCLSKLPHEVAKLKEVCDATLSHYPTHPYPLEALSEHYIQTGDCSEEAVSCFKRLLELDPNNSYAHFGLGIKACQDKKYEDAIKNIGLGLKRMRFSIIGWYNLALAQLKMHKYSDSAISSSQGLKS-----SVGNADDWTQKLLRLKLEALVKTGREQDADEALQILALISDAKNDPVVLALKGRAYLEKGQTEEAFQVSTELLSSHPGSVDGLTLKALLHVAKEQHKQAEESFLEALSRSPDSGELFFLLGSLYWNMGEEIRRDRSK--THLLKAAKLDPYLGSVFRLLGHYYREVAKDQGRARGCYKRAFELDPSDAEAGAAAVDLSMEQGDMDSALTVLQSVTERATPGSAKWAWMRRGLYHLKIGQHQQAIADLQAALRADPQDWVCWECLGEAYLNRRSFTAALKAFDKAHVLQPTSIYSLYQTAAIKQILGRFKEAAAEYKQILE-KEDYVPALKGLGECLLALAKSALDDYLDGRAVDLIQNAIHYLFRAVKQRPDLSCLWKLLGDSCTASRTVSPNRAKVLVPGALCGMDPSDQKHTLDQRQLLTLGERCFGRALKLMPEAPSLWCDLGLNYYHQSRLLSSHYPEE-DPQALLEKALQCVKKAIMLDSANHTYWNALGVVAMTKGIENFALAQHSFIKSVKAEPNNVVAWTNLGALYLKKGNIELSHEAFKIAQSLEPLYVNCWIGQALIAETVGSYDTMDLFRHTTELSTHTEGVKGYAYCVCSTLLDRSNRDSELYLYNIVQMNAVSAAQVALSKYTERIQTDPDAFIMLGYLNTHLQLRKQATEAYHRAVELLQGSLHTDKLSFALRGYGRALSDDGQWEEAVRIYCSTPLEELHDLIGLALACFRIGRLPESIQAYEKALVVASTEKEKAYILTALALIQHKLGSMDHAKTLLFKCSMLKEPVQESLQCLCALGLVHGDVTLASATVTELLKLGEPAGSAVEDRCLLTCTLLALQGNFSGVHREASRAIHRNPGNPSLWALLSRLVPQYCPNKADGGAVAGNVACQASLTLGKRALLYSGVNQLASGRHSGEDRRHNALKTIQRAVLLCPDDPAGWAGLMAACHTENTACFLTGSTPHREDLERAHMALVSEKVKGLQGEDGLLAQALEGWVLQQAVTGLKLSGQYDQAEALCSQVLSVSPEHPVVFLMLRQVQCERLLLSEAGSCIPPAVLDQLSAAVMANHTSVAAWHWLAEVYRSQGLLAQASVAYKQSLQLASQLGDHSGKMSSLLRLSLLALTPCLAGVGVSDWKDLVSEATGEVLKMSKSPVALLFQALLQFSVKMGARETRRLLERIVYASALGGSETIASVARWYLLRHLHAKDDLELIDTLLVKATAAGDSRLVDFHRRLYPSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *******: **.**:**:***:********:*** ***************:**:****** **:**:****:*********.**** :: : * :** :****: ***: *: * :* **** :* .**::*:***.*::**:.:: *:* : ** :**::::::* :. :**:***** *::***.** :: .:*** *: * :.:*:.***:*** ::**:.*: : *** ****.:. : *::*. :.*. . :*:*::.:.. . :**** * ********:::: ***. .. ** :** **:***: .:: :*..*.** : *. : *:** ***:* . .::**:: * :**..* * :*.*:. * :.* ::* :: :*::*:*. .: :*:. :*.:*::: *** .* .**.:..: .* .: ** ** **** *:*::* **:****:**.::*.** ******:*. *:.******::***** .***:********:* * : **::* :**::*:.*:*****:*****:** ***.**:***********:* ***.******.* .:*:***:* ** *:* * **:::.***:****::.** *:*: *:: ************** * :.* ** *:***:*** :::*: *: *:::*.*:****** **:**. .*:*.:.:* * *.* * .: :..*.:.:** ** **:*******. : . *****:***:* : *:. .. * ****:*:*:***: *** ** :******** *: *:*****.****:::* *..******.*** . *** :*****:****:* *: ********** ****************. ****. **** **:** *:***::*** ***::***:.*** * **.****. . ** ****** ****:*:*::**:** **: : . :. ..*:*.:** *.. *:::.*:: : **** *.*:**:*** * * ** .***:** : .:*::**:****:*: ::* *. * **::*****:****. ****.******. *.**:.*::.**** : . . *** .:: ****. .*::: ::*:* **.:*:**:****:*.** ..*.**.****** . . **:****:.***** * :.**. :.******:*.:*.*.*** *********:::. .::..: *:* ** * : *: .:*. : :. *:** * :.*.**** :*: .:**:**:: *. .*::*.*:*:****** ** *: :* ***::*. :**:* ***.**:***.**:***:: *.:.*::***:*** *. ***:****:*:**** *:*.:. ..* .**.*** *.**:. .*:*:::******. *************:** .. * *.*.*********:**** ****.*: :* : **.* ::::::* .. ", "identical_positions": 812, "similar_positions": 467, "identity": "50.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110125-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ABL6-1", "uniprot_id": "MCTP1_RAT", "id": "D4ABL6-1", "name": "Multiple C2 and transmembrane domain-containing protein 1", "aln": "MEPRGAAAGEPEP-AVSPSFQARLWKNLQLGVGKGKGGGGGRAGGPERRTAATPTPSLPPPKTTQD----VGSTG-SRWSGFKKRKQVLDRVFSSSQPNLCCSSPEPLEPGGAGRAEQGSTLRRRLREHLLPVAKGSSTAAGTVGVTPPGGRSPDSAPSSS-ASSSLSSSPQPPPRGDRIRDEGTRRGSPEAHLCHQKSSSLPGTACLEQLLEPAPPPAEPARRPAEPQSLQKGEELDCSQKIN-PVETSNADVPLADPGMYQLDITLRRGQSLAARDRGGTSDPYVKFKIGRKEVFRSKIIHKNLNPVWEEKACVLIDHLREPLYIKVFDYDFGLQDDFMGSAFLDLTQLELNRPTDVTLTLKDP-HYPDHDLGIILLSVILTPKEGEPRDVTMLMRKSWKRSSK----------------------------------------------FQTQSLRLSDQHRKSHLWRGIVSITLIEGRDLKAMDSNG-LSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYEERGGVMDITAWDKDAGKRDDFIGRCQVDLSSLSREQTHKLELQLEEGEGHLVLLVTLT-ASATVSISDLSVNSMEDHKEREEILKRYSPLRIFNNIKDVGFLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTFNIKDIHSVLEVTVYDEDRDRSADFLGRVAIPLLSIQNGEQKAYVLKNKQLTGPTKG---VIHLEIDVIFNAVKASLRTLIPKERKYIEEENRLSKQLLLRNFIRTKRCVMVLVNAAYYVNSCFDWDSPPRSLAAFVLFLLVVWNFELYMIPLLLLLLLTWNYFL-IISGKDNRQRDT-VVEDMLEDEEEEDDRDDK----------------------------------DGEKKGFINKIYAIQEVCVSVQNILDEAASLGERVKNTFNWTVPFLSWLAIIALCVFTAILYFIPLRYIVLVWGINKFTKKLRSPYAIDNNELLDFLSRVPSDVQVVQYQELKPDH--SHSPYKRKKNNLG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PV86-1", "uniprot_id": "MCTP1_MOUSE", "id": "E9PV86-1", "name": "Multiple C2 and transmembrane domain-containing protein 1", "aln": "MEPRAATTGELVR-AASPSFQARLWKNLQLGVGKGKGGGGGRAGGPEHRTAATPTPSPPPPGTTQDALAGVGSTG-SRWSGFKKRKQVLDRVFSSSQPNLCCSSPEPLEPGGAGRAEQGSTLRRRLREHLLPVAKGSSTATGTGGVTPPGGRSPDSAPSSSSASSSLSSSPQPPPRGDRVRDESTRRGGPGVHLCHQKSSSLPGTACLEQLLEPAPPPAEPARGPAEPQALQKDIERDCSQKIS-TVGNSNADVPLADPGMYQLDITLRRGQSLAARDRGGTSDPYVKFKIGRKEVFRSKIIHKNLNPVWEEKACVLIDHLREPLYIKVFDYDFGLQDDFMGSAFLDLTQLELNRSTDVTLTLKDP-HYPDHDLGIILLSVILTPKEGEHRDVTMLMRKSWKRSSK----------------------------------------------FQTQSLRLSDQHRKSHLWRGIVSITLIEGRDLKAMDSNG-LSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYEERGGIMDITAWDKDAGKRDDFIGRCQVDLSSLSREQTHKLELHLEEGEGHLVLLVTLT-ASATVCISDLSVNSMEDQKEREEILKRYSPLRIFNNLKDVGFLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTFNIKDIHSVLEVTVYDEDRDRSADFLGRVAIPLLSIQNGEQKAYVLKNKQLTGPTKG---VIYLEIDVIFNAVKASLRTLIPKERKYIEEENRLSKQLLLRNFIRTKRCVIVLVNAAYYVNSCFDWDSPPRSLAAFVLFLLIVWNFELYMIPLLLLLLLTWNYFL-IISGKDNRQRDT-VVEDMLEDEEEEDDRDDK----------------------------------DGEKKGFINKIYAIQEVCVSVQNILDEVASLGERIKNTFNWTVPFLSWLAIVALCVFTAILYFIPLRYIVLVWGINKFTKKLRSPYAIDNNELLDFLSRVPSDVQVVQYQELKPDH--SHSPYKRKKNNLG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6DN14-1", "uniprot_id": "MCTP1_HUMAN", "id": "Q6DN14-1", "name": "Multiple C2 and transmembrane domain-containing protein 1", "aln": "MEPRAAAAGEPEPPAASSSFQARLWKNLQLGVGRSKGGGGGRAGGPERRTADTPSPSPPPPVGTGNAPARGSGAG-SRWSGFKKRKQVLDRVFSSSQPNLCCSSPEPLEPGGAGRAEQGSTLRRRIREHLLPAVKGPAAASGAAGGTPPGGRSPDSAPSSSSASSSLSSSPQPPPRGDRARDEGARRQGPGAHLCHQKSSSLPGTACLEQLLEPPPPPAEPARSPAESRAPETGEEHGSSQKIINTAGTSNAEVPLADPGMYQLDITLRRGQSLAARDRGGTSDPYVKFKIGGKEVFRSKIIHKNLNPVWEEKACILVDHLREPLYIKVFDYDFGLQDDFMGSAFLDLTQLELNRPTDVTLTLKDP-HYPDHDLGIILLSVILTPKEGESRDVTMLMRKSWKRSSKELSENEVVGSYFSVKSLFWRTCGRPALPVLGFCRAELQNPYCKNVQFQTQSLRLSDLHRKSHLWRGIVSITLIEGRDLKAMDSNG-LSDPYVKFRLGHQKYKSKIMPKTLNPQWREQFDFHLYEERGGVIDITAWDKDAGKRDDFIGRCQVDLSALSREQTHKLELQLEEGEGHLVLLVTLT-ASATVSISDLSVNSLEDQKEREEILKRYSPLRIFHNLKDVGFLQVKVIRAEGLMAADVTGKSDPFCVVELNNDRLLTHTVYKNLNPEWNKVFTFNIKDIHSVLEVTVYDEDRDRSADFLGKVAIPLLSIQNGEQKAYVLKNKQLTGPTKG---VIYLEIDVIFNAVKASLRTLIPKEQKYIEEENRLSKQLLLRNFIRMKRCVMVLVNAAYYVNSCFDWDSPPRSLAAFVLFLFVVWNFELYMIPLVLLLLLTWNYFL-IISGKDNRQRDT-VVEDMLEDEEEEDDKDDK----------------------------------DSEKKGFINKIYAIQEVCVSVQNILDEVASFGERIKNTFNWTVPFLSWLAIVALCVFTAILYCIPLRYIVLVWGINKFTKKLRSPYAIDNNELLDFLSRVPSDVQVVQYQELKPDP--SHSPYKRKKNNLG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B9W7-1", "uniprot_id": "A0A8M3B9W7_DANRE", "id": "A0A8M3B9W7-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MLALSLSSVGQSLS----------------------GINIVEPSNDELP---------------------------------------------------PLPKPRMYQLDIVLKKGNNLAIRDRGGTSDPYVKFKIAGKEVFRSKTIHKNLNPVWEEKVSLLVESLREPLYVKVFDYDFGLQDDFMGSAYLYLESLEHQRTLDVTLDLKDP-HYPKQDLGSLELAVTLIPKEGDFREATMLMRRSWKRSSK------------------------------------------------HQSLRLSDVHRKSQLWRGIVSISLIEAHDLQPMDNNG-LSDPYVKFRMGHQKYKSKTIPKTLNPQWREQFDFHLYDEQGGFVDITVWDKDAGKKDDFMGRCQVDLSLLSKECTHRLDLPLEEGEGMLVLLVTLT-ASAAVSIADLSVNVLDDPHERKEILHRYNVLRSFHNIKDVGMVQVKVIRAEGLMAADVTGKSDPFCVVELSNDRLQTHTVYKNLNPEWNKVFTFNVKDIHSVLEVTVYDEDRDRSADFLGKVAIPLLNIQNGERKAYALKSKELTGPTKG---VIFLEIDVIYNVVKAGMRTLIPIEQKYIEEEPRVSKQLLLQNFNRVRRCIMFLINAGCYINSCFEWESPQRSICAFLLFVLVVWNFELYMVPLVLLMLLAWNYIL-IASGKDTRQGDVQAVEDLLEDEDEDFDRDDKVPGSVPSQDGRLPESHILADILASWHFEWIRVMVDSERKGFMNKLYAIQDVCISVQNALDEVASYGERIKNTFNWTVPFLSWLAIVALCVVTLVLYFIPLRYIVLAWGVNKFTKKLRDPYSIDNNELLDFLSRVPSDVQVMQYRELKVDP--CHSPNKRKKNNPG-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZBD6-1", "uniprot_id": "MCTP_DROME", "id": "A1ZBD6-1", "name": "Multiple C2 and transmembrane domain-containing protein", "aln": "---------MSRIQYVDQVDQVELDQQQQPGSSSTVSG-----STPPLQISPHGSPSLQQSQRLGKHLSKSASELNGHDCHLSESPHISPKRAKSAVAQQLAGVSSGGVASGVGVLQKTHGFFNNLRHRWSRAK--SKDRLGRKSPSDFLEESTDYAADYSSEGSSVTHSPR--HRSTTIGGSPLAREFRATAKMAQVIQRFGG--SMEGRIDEHPENGSAGCSPPELSTQQQLEALQANELRR------KREAQLRQFVFFQLRVHLKSGSDLVAMDKNGLSDPYVKFKVGGRLLHKSRTIHRDLNPVWDEVFIVPIEDPFQPIIVKVFDYDWGLQDDFMGSAKLDLTQLELGKAEDIHLQLCDSSGNGGSGLGEILINLTLWPRSQE--DKEMHFQRNSK-------------------------------------------------------LAESSKRLKSQIWSSVVTILLVKAKDLPLAEDGSKLNDTHFKFRLGNEKYKSKSS---WTERWLEQFDLHLFDE-DQNLEIALWN-----RNTLYGKAIIDLSVFQRENTHGIWKPLEDCPGEVHLMLTISGTTALETISDLKA-FKEDPREAQLLRERYKFLRCLQNLRDVGHLTVKVFGATGLAAADIGGKSDPFCVLELGNARLQTQTEYKTLTPNWNKIFTFNVKDITQVLEITVFDEDRDHRVEFLGKLVIPLLRIKSGVKRWYTLKDKNLCVRAKGNSPQIQLELTVVWSEIRAVCRALQPKEEKLIQQEAKFKRQLFLRNVNRLKEIIMDILDAARYVQSCFEWESPVRSSIAFVFWIVACVYGDLETVPLVLLLIILKNWLVRLITG----TTDAAAHYDYEYDEDDDDDKEKE------------------------------------EKKSIKERLQAIQEVSQTVQNTIGYLASLGESTINTFNFSVPELTWLAVVLLLGAILVLHFVPLRWLLLFWGLMKFSRRLLRPNTIPNNELLDFLSRVPDNEEINQYRELPPSAPTDQTRNNPKKKLKGS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * ..*:: . : * . ::** : *: *..*. *:.* ********:. : :.:*: **::*****:* : :: :*: :******:********** * * .** :. *: * * *. .** : : : * *:. : : * :::. * * *. : **::* .:*:* *::.:** :... *.*.:.***:*::***** . :* ****:**::* . ::*: *: :: : *:. :*** :.:* ** : **: * : *::*:: ::* *:**.. :* :* : : .**. ** ::*::*** : ***: * ** ***: ********:**.* ** *:* **.*.*:***:****:*** .***:**:*****: .:***::.**** *:.* :: *.**.*:* :** * **: *::. ::* *:* * *.* *::* :..:**:*:*. * :. :: :::*. *::***:*:** ** **::::. :* :**:**::: *::: : :* *. . * **::: *::.: *:*.: ::: ***:*. :*** :. ** ** ****::** *:***:: * :*: :***:::* **: **:::* * :* ************.: :: **:** . :: : **: * ", "identical_positions": 276, "similar_positions": 233, "identity": "26.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110126-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35585-1", "uniprot_id": "AP1M1_MOUSE", "id": "P35585-1", "name": "AP-1 complex subunit mu-1", "aln": "MSASAVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDSKILQEYITQEGHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIEAVNLLVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMVKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSVKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXS5-1", "uniprot_id": "AP1M1_HUMAN", "id": "Q9BXS5-1", "name": "AP-1 complex subunit mu-1", "aln": "MSASAVYVLDLKGKVLICRNYRGDVDMSEVEHFMPILMEKEEEGMLSPILAHGGVRFMWIKHNNLYLVATSKKNACVSLVFSFLYKVVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDSKILQEYITQEGHKLETGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIESVNLLVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFDNTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVPNDADSPKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IRS1-1", "uniprot_id": "A0A0R4IRS1_DANRE", "id": "A0A0R4IRS1-1", "name": "AP-1 complex subunit mu-1", "aln": "MSASAVYVLDLKGKVLICRNYRGDVDMSEIEHFMTLLMDKEEEGTLSPILAHGGVRFMWIKHNNLYLVATSKKNACVSLVFSFLYKIVQVFSEYFKELEEESIRDNFVIIYELLDELMDFGYPQTTDSKILQEYITQEGHKLDTGAPRPPATVTNAVSWRSEGIKYRKNEVFLDVIESVNLLVSANGNVLRSEIVGSIKMRVFLSGMPELRLGLNDKVLFENTGRGKSKSVELEDVKFHQCVRLSRFENDRTISFIPPDGEFELMSYRLNTHVKPLIWIESVIEKHSHSRIEYMIKAKSQFKRRSTANNVEIHIPVPTDADSPKFKTTVGSVKWVPENSEIVWSIKSFPGGKEYLMRAHFGLPSVEAEDKEGKPPISVKFEIPYFTTSGIQVRYLKIIEKSGYQALPWVRYITQNGDYQLRTQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****************************:****.:**:***** *****************************************:*******************************************************:**********************************:******************************************:*************************************************************************:**********************.**************************:******************************************************************************", "identical_positions": 411, "similar_positions": 11, "identity": "97.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110126-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIL0-1", "uniprot_id": "RN167_RAT", "id": "Q5XIL0-1", "name": "E3 ubiquitin-protein ligase RNF167", "aln": "-MHPAAFPLPVVVATVLWG---AAPIRGLIRATSEHNASMDFADLPALFGATLSDEGLQGFLVEAH-PENACSPIAPPPSAPVNG-----SVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSAEYLRALFVYEKGARVLLVPDNSFPLG-YYLIPFTGIVGLLVLAMGTVLIVRCIQHRKRLQRNRLTKEQLKQIPTHDYQKG---DEYDVCAICLDEYEDGDKLRILPCAHAYHSRCVDPWLTQTRKTCPICKQPVHR------GPGDEEQEEETQGQEEEGDEGEPRDQPASEWTPLLGSSP------TLPTSFGSLAPAPLVFPG-PSTDPSPSPSSAALA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XF4-1", "uniprot_id": "RN167_MOUSE", "id": "Q91XF4-1", "name": "E3 ubiquitin-protein ligase RNF167", "aln": "-MHPAAFPLPVVVATVLWG---AAPVRGLIRATSEHNASMDFADLPALFGATLSDEGLQGFLVEAH-PENACGPIAPPPSAPVNG-----SVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSAEYLRALFVYEKGARVLLVPDNSFPLG-YYLIPFTGIVGLLVLAMGTVLIVRCIQHRKRLQRNRLTKEQLKQIPTHDYQKG---DEYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHR------GPGDEEQEEETQEQEE-GDEGEPRDQPASEWTPLLGSSP------TLPTSFGSLAPAPLVFPG-PSTDPSP-PSSAALA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H6Y7-1", "uniprot_id": "RN167_HUMAN", "id": "Q9H6Y7-1", "name": "E3 ubiquitin-protein ligase RNF167", "aln": "-MHPAAFPLPVVVAAVLWG---AAPTRGLIRATSDHNASMDFADLPALFGATLSQEGLQGFLVEAH-PDNACSPIAPPPPAPVNG-----SVFIALLRRFDCNFDLKVLNAQKAGYGAAVVHNVNSNELLNMVWNSEEIQQQIWIPSVFIGERSSEYLRALFVYEKGARVLLVPDNTFPLG-YYLIPFTGIVGLLVLAMGAVMIARCIQHRKRLQRNRLTKEQLKQIPTHDYQKG---DQYDVCAICLDEYEDGDKLRVLPCAHAYHSRCVDPWLTQTRKTCPICKQPVHR------GPGDEDQEEETQGQEE-GDEGEPRDHPASERTPLLGSSP------TLPTSFGSLAPAPLVFPG-PSTDPPLSPPSSPVILV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BCW7-1", "uniprot_id": "A0A8M2BCW7_DANRE", "id": "A0A8M2BCW7-1", "name": "E3 ubiquitin-protein ligase RNF167", "aln": "-MVCLGSPLAVSVLLIIFCTLVPSPGQAYIYAHYSNMTSMLFEDLPALFGSALPKDGLMGVLIEAR-PQNACTPIDPPPASPTPADPNSTTKYIVLIRRYDCNFDVKVYHAQQAGYSAAIVHNMYSNSLLNMGYSNETIAEEISIPSVFTSFFASQMLHKIIP-EKGAYVVLKPEFSFPLS-YYLIPFTGVVCMIIIVMVIIMIVRCVQHRKRLRKNRLSKEQLKKIPIHKFNKG---DSYDVCAICLDEYEEGDKLRVLPCSHAYHSRCVDPWLTQTKKTCPVCKQRVTRPNPEYSESSDSDEEAGPHDAEE-EDERTPLLRPSNPGSPASSSPPPSYSS-TVASEPATVTTAAQCLPHTPQHDAPLLANDEYYSPIEDSDDEGSEDEEEGHASESDTTELIGGAAVRV------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VI20-1", "uniprot_id": "GZL_DROME", "id": "Q9VI20-1", "name": "E3 ubiquitin-protein ligase Godzilla", "aln": "MSKRSCQILTLLGLCLVCHEATLVGGHVLVYRKATSQLIEEFNDLPAQFGPNLPSNGLKVYVVPARRPYYGCDSLDRPPHLKYPP----SAKFVALVARGECVFERKIRVAQNASYSAVIVYNNEGDDLEQMSAEN---ITGIRIPSVFVGHTTGKALATYFT--TEVVLIINDELPFNINTQLILPFSILIGMCFIIMVIYMIYKCIREQRRLRRHRLPKSMLKKLPVLRYTKNNANNKYDTCVICLEDFIEDDKLRVLPCSHPYHTHCIDPWLTENRRVCPICKRKVFTKG---EARASRSRQPSLDNVTDTDDDTTPLLQQQQSNGRQVGQVSSASSAGGAAGSSSSVAAAAVAGTTRHGTFRRGHAGRNPFEESQSSDDENALLASTVRPATSSGAHERINPFDRAPNLPAHLAEQLTESRRSVWSRINFASFFRRQPAVISVAAPPYLERVESGTSAMGLPVTGTIAVASPASNNILNPNLSGSFKDEDDMPPHRSIYEPIAISTPAADSATVDDSAFLQTPTQGGIGVAALPHSASDRQFLI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.: :: : : * **** **. *..:** :: *: * .* .: ** : ::.*: * :* *: *: **:*.*.*.:*:* .:.* :* .. * ***** . :.: * : . . ::: : .* :. ::**: :: : .: * :* :*::.::**:::**.*. **::* : *. :.**.*.***::: :.****:***:*.**::*:*****:.::.**:**: * .. ..: . : *: * : . .. . . . .:::.*. . . ", "identical_positions": 82, "similar_positions": 119, "identity": "14.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110127-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P41586-1", "uniprot_id": "PACR_HUMAN", "id": "P41586-1", "name": "Pituitary adenylate cyclase-activating polypeptide type I receptor", "aln": "--MAGVVHVSLAALLLLPMAPAMH---SDCIFKKEQAMCLEKIQRANELMGFNDSSPGCPGMWDNITCWKPAHVGEMVLVSCPELFRIFNPDQVWETETIGESDFGDSNSLDLSDMGVVSRNCTEDGWSEPFPHYFDACGFDEYESETGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSNHCFISTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWATLRLYFDDTGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIVILVQKLQSPDMGGNESSIY----------------------------LRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAE----IKRKWRSWKVNRYFAVDFKHRHPSLASS--GVNG----GTQLSILSKSSSQ--IRMSGLPADNLAT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P70205-1", "uniprot_id": "PACR_MOUSE", "id": "P70205-1", "name": "Pituitary adenylate cyclase-activating polypeptide type I receptor", "aln": "--MARTLQLSLTALLLLPMAIAMH---SDCIFKKEQAMCLERIQRANDLMGLNESSPGCPGMWDNITCWKPAQIGEMVLVSCPEVFRIFNPDQVWMTETIGDSGFADSNSLEITDMGVVGRNCTEDGWSEPFPHYFDACGFDDYEPESGDQDYYYLSVKALYTVGYSTSLVTLTTAMVILCRFRKLHCTRNFIHMNLFVSFMLRAISVFIKDWILYAEQDSSHCFVSTVECKAVMVFFHYCVVSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTVCVTVWAVLRLYFDDAGCWDMNDSTALWWVIKGPVVGSIMVNFVLFIGIIIILVQKLQSPDMGGNESSIYFSCVQKCYCKPQRAQQHSCKMSELSTITLRLARSTLLLIPLFGIHYTVFAFSPENVSKRERLVFELGLGSFQGFVVAVLYCFLNGEVQAE----IKRKWRSWKVNRYFTMDFKHRHPSLASS--GVNG----GTQLSILSKSSSQ--LRMSSLPADNLAT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58GT21-1", "uniprot_id": "A0AC58GT21_DANRE", "id": "A0AC58GT21-1", "name": "", "aln": "MYRQAARETFLILFLIISLMWPIHSEISNCVIKREEERCLERIALHDPKD---DQKFECPWEWDNLTCWQAASVGDVVEVNCPELFEFMSPE---------------------EGLGKISRNCTEFGWSEPYPHYVDACMTDEN---TTKPDMYYASVKALYTVGYSTSLVSLTTAMVILCRFRKLHCTRNFIHMNLFVSFILRAISVFIKDGVLYAEEDSDHCFVHTVGCKAVMVFFHYCVMSNYFWLFIEGLYLFTLLVETFFPERRYFYWYTIIGWGTPTICVTIWAVLRLHFDDSGCWDMNDNTALWWVIKGPVVASIMINFVLFIGIIIILVQKLQSPDIGGNESSIYLSCAQKCFSEPTQAVQHSCRMSELSTITLRLARSTLLLIPLFGIHYTVFAFSPEDFSKRERLVFELGLGSFQGFVVAVLYCFLNGEFLPKGAVGDKEEMEELDGEQVLCCGPEAAASPFASEQWGERGDAAVHPQQEQLSDTHVQPSGRDSQPQPANLSA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * :*::.: .:* *:*::*:*: ***:* : :.. ** ***:***:.* :*::* *.***:*.::.*: .:* :.***** *****:***.*** *: : . * ** ***************:*****************************:********** :****:**.***: ** ************:****************************************:***:**.***:***:*******.************.***:*********:**********:******** **************************:.******************************. .: *.: .. . :: : . : ..:**. * .* .* . **.: * * * . **::", "identical_positions": 295, "similar_positions": 85, "identity": "57.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110127-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P32082-1", "uniprot_id": "GHRHR_MOUSE", "id": "P32082-1", "name": "Growth hormone-releasing hormone receptor", "aln": "-MDGLMWATR--ILCLLSL-----CGVTLGHLHLECDFITQLRDDELAC--LQAAEGTN-NTSLGCPGTWDGLLCWPPTGSGQWVSLPCPEFFSHFGSDTGFVKRDCTITGWSNPFPPYPVACPVPLELLTK-EKSYFSTVKIIYTTGHSISIVALCVAIAILVALRRLHCPRNYIHTQLFATFILKASAVFLKDAAIFQGDSTDHCSMSTVLCKVSVAISHLATMTNFSWLLAEAVYLSCLLASTSPRSKPAFWWLVLAGWGLPVLCTGTWVGCKLAFEDTECWDLDNSSPCWWIIKGPIVLSVGVNFGLFLNIICILLRKLEPAQGGLHTRAQYWRLSKSTLLLIPLFGIHYIIFNFLPDSAGLDIRVPLELGLGSFQGFIVAVLYCFLNQEVRTEISR---KWYGHDPELLPARR--------TCTEWTTPPRSRLKVLTSEC--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02643-1", "uniprot_id": "GHRHR_HUMAN", "id": "Q02643-1", "name": "Growth hormone-releasing hormone receptor", "aln": "-MDRRMWGAH--VFCVLSP-----LPTVLGHMHPECDFITQLREDESAC--LQAAEEMP-NTTLGCPATWDGLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLAE-EESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVFLKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRRAFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLFLNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPLELGLGSFQGFIVAILYCFLNQEVRTEISR---KWHGHDPELLPAWR--------TRAKWTTPSRSAAKVLTSMC--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FF79-1", "uniprot_id": "E7FF79_DANRE", "id": "E7FF79-1", "name": "", "aln": "MIFFRTWSTVRLVTVLLSLGIHKSTWKAVETIHPACALVAAHMKAQEQCNATQRQESQNRNNVTGCPTEWDEFWCWSGAEVGQVVNISCSEVSQLFVN-HGFIFRNCTKDGWTEVYPSYENACEIVEDVESETETTYYATFRQVYTAGYATSLISLITAIFVFTVFRKFHCTRNYIHINLFASFILRASAIFIKDAVLFADENLDHCFMSTTSCKAAVAFFQFSILANYFWLLVEGMYLQTLLALTFVSQKKYFWWYILIGWGLPTLILTIWVLARNFFDNNGCWDDTDVAYFWWIIKGPITVSLLINFLIFINVIRILVQKLKSPGMGGGDTNHFMRLAKSTLFLIPLFGMHYMVFAFLPENTGENARHFLELGLGPFQGFVVALLYCFLNGEVQAELKKRLWKWQTQSYLRYSKRRRTLFTESSTVTQISVLEKSSPKELPLTESNNSVSTV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.: : :** .: :* * ::: . : * * * *. *** ** : **. : *: *.:.*.:. . * . * : *:** **:: :*.* ** : :: :: * :*::*.: :**.*:: *:::* .** ::..:*::**.***:* :**::***:*.*:*:***.:* .:. *** :**. **.:** ::: ::*: ***.*.:**. *** * .: *** :* *****.* ** .: *:: *** : : ********.:*: :** :*:*:* **::**:.. . :: **:****:******:**::* ***:.:* . * ******.****:**:****** **::*:.: ** :. . * * :: :. :* * *. ", "identical_positions": 161, "similar_positions": 136, "identity": "35.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110127-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q03555-1", "uniprot_id": "GEPH_RAT", "id": "Q03555-1", "name": "Gephyrin", "aln": "MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPEKFPTFPFCGLQKGATKEVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAALAAK---------------------------------------IPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTPKQIRRPDESKGVASRVGSL-----------------------------------------KVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYR----------------------------------------------------DGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQP-TQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPG----------------------------------NPVSAVVTCNLFVVPALRKMQGILDPRP--TIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9NQX3-1", "uniprot_id": "GEPH_HUMAN", "id": "Q9NQX3-1", "name": "Gephyrin", "aln": "MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPE-------------ATKEVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAAIAAK---------------------------------------IPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTP------------------------------------------------------------KVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYR----------------------------------------------------DGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQP-TQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPG----------------------------------NPVSAVVTCNLFVVPALRKMQGILDPRP--TIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BUV3-1", "uniprot_id": "GEPH_MOUSE", "id": "Q8BUV3-1", "name": "Gephyrin", "aln": "MATEGMILTNHDHQIRVGVLTVSDSCFRNLAEDRSGINLKDLVQDPSLLGGTISAYKIVPDEIEEIKETLIDWCDEKELNLILTTGGTGFAPRDVTPE-------------ATKEVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDELEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEEEEKKDSGVASTEDSSSSHITAAALAAK---------------------------------------IPDSIISRGVQVLPRDTASLSTTPSESPRAQATSRLSTASCPTPKQIRRPDESKGVASRVGSLKARLPSCSSTYSVS---------------------------EVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYR----------------------------------------------------DGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQP-TQTVMPGQVMRVTTGAPIPCGADAVVQVEDTELIRESDDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVNKFPVVAVMSTGNELLNPEDDLLPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGVRKIIFALPG----------------------------------NPVSAVVTCNLFVVPALRKMQGILDPRP--TIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PE84-1", "uniprot_id": "A0A8M9PE84_DANRE", "id": "A0A8M9PE84-1", "name": "Gephyrin", "aln": "MASDGMILTNHDHQIRVGILTVSDSCFRNLAEDRSGINLKDLVHDPSLLGGIISAYKIVPDEIDEIKEILVDWCDEKELNLILTTGGTGFAPRDVTPE-------------ATREVIEREAPGMALAMLMGSLNVTPLGMLSRPVCGIRGKTLIINLPGSKKGSQECFQFILPALPHAIDLLRDAIVKVKEVHDALEDLPSPPPPLSPPPTTSPHKQTEDKGVQCEEEDEEKKDSGVASTEDSGSSHITAAAIAAKSMTSHLSHAVVMAKGGQPLSGFIPSTSIPSHFTCSCSDTIPESIISRGVQVLPRDTASLSTTPSESPCAQQ-SRLSTASCPTPKARLTSCSSTYSVTEASRREFRAHLDDVISHKSRYSTLDQLHSRLEGLKDDRRNHRTFDSRVQSRCSSKENILRASHSAVDITKVARRHRMSPFPLTSMDKAFITVLEMTPVLGTEIINYRGPYTGDLAPLPRKGIWRQNGSSWRKIPLCTGAEAKAERRALANAAHTPKYCTDGMGRVLAQDVYAKDNLPPFPASVKDGYAVRAADGPGDRFIIGESQAGEQP-TLTVMPGQVMRVTTGAPIPCGADAVVQVEDTELLRESEDGTEELEVRILVQARPGQDIRPIGHDIKRGECVLAKGTHMGPSEIGLLATVGVTEVEVQKFPVVAVMSTGNELLNPEDDLHPGKIRDSNRSTLLATIQEHGYPTINLGIVGDNPDDLLNALNEGISRADVIITSGGVSMGEKDYLKQVLDIDLHAQIHFGRVFMKPGLPTTFATLDIDGARKLIFALPGNFTYRDTGATLLEAVPLSDTEACRMPVPPPPRGSNPVSAVVTCNLFVIPALRKMQGILDPRP--TIIKARLSCDVKLDPRPEYHRCILTWHHQEPLPWAQSTGNQMSSRLMSMRSANGLLMLPPKTEQYVELHKGEVVDVMVIGRL------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P39205-1", "uniprot_id": "CIN_DROME", "id": "P39205-1", "name": "Molybdenum cofactor synthesis protein cinnamon", "aln": "-----------MESITFGVLTISDTCWQEPEKDTSGPILRQLIGET--FANTQVIGNIVPDEKDIIQQELRKWIDREELRVILTTGGTGFAPRDVTPE-------------ATRQLLEKECPQLSMYITLESIKQTQYAALSRGLCGIAGNTLILNLPGSEKAVKECFQTISALLPHAVHLIGDDVSLVRKTHAEVQGS-------AQKSHICPHKTG----------------TGTDSDRNSP------------------------------------------------------------YPMLP-------------------------------------------------------------------------------------------VQEVLS---IIFNTVQKTANLNKIL--------------------LEMN---------------------------------------------------------------------------APVNIPPFRASIKDGYAMKSTGFSGTKRVLGCIAAGDSPNSLPLAEDECYKINTGAPLPLEADCVVQVEDTKLLQLDKNG-QESLVDILVEPQAGLDVRPVGYDLSTNDRIFPALDPSPVVVKSLLASVGNRLILSK--PKVAIVSTGSELCSPRNQLTPGKIFDSNTTMLTELLVYFGFNCMHTCVLSDSFQRTKESLLELFEVVDFVICSGGVSMGDKDFVKSVLE-DLQFRIHCGRVNIKPGKPMTFASR----KDKYFFGLPG----------------------------------NPVSAFVTFHLFALPAIRFAAGWDRCKCSLSVLNVKLLNDFSLDSRPEFVRASVISKSGE--LYASVNGNQISSRLQSIVGADVLINLPARTSDRPLAKAGEIFPASVLRFDFISKYE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..* .*:**:**:*::: :* ** *::*: :. :.. :***** : *:: * .* *.:**.:***************** **::::*:*.* ::: : : *:: * . *** :*** *:***:*****:*. :**** * . ****:.*: * : *::.* ::. : . .*** :*. * .:* :** **. * *:.: :.:.::.*: ***. * *:*** **:*****::::. .* : ::* **:.* : .: .: ::.****:* **.*******:*:: ..:* :* * ***:.:.* *:**:*:*:. .: ::. .***:** : : * **::***.** .*.::* **** *** : * : .*: :: ::.*. : ::* * :. .*.:* *******:**::*.**: **: :** *** :*** * ***: * :*.*** *****.** :**.:**:* * : ::::.:* *..**.***: *. : : * :*. .***:**** *: .*: *: **.:*.: : **:. . *: ", "identical_positions": 235, "similar_positions": 199, "identity": "24.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110127-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08675-1", "uniprot_id": "PAR3_MOUSE", "id": "O08675-1", "name": "Proteinase-activated receptor 3", "aln": "MKILILVAAGLLFLPVTVCQSGIN-VSDNSAKPTLTIKSFNGGPQNTFEEFPLSDIEGWTGATTTIKAECPEDSISTLHVNNATIGYLRSSLSTQVIPAIYILLFVVGVPANIVTLWKLSLRTKSISLVIFHTNLAIADLLFCVTLPFKIAYHLNGNNWVFGEVTCRITTVVFYGNMYCAILILTCMGINRYLATAHPFTYQKLPKRSFSMLMCGMVWVMVFLYMLPFVILKQEYHLVHSEITTCHDVVDACESPSSFRFYYFVSLAFFGFLIPFVIIIFCYTTLIHKLKSKDRIWLGYIKAVLLILVIFTICFAPTNIILVIHHANYYYHNTDSLYFMYLIALCLGSLNSCLDPFLYFVMSKVVDQLNP---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00254-1", "uniprot_id": "PAR3_HUMAN", "id": "O00254-1", "name": "Proteinase-activated receptor 3", "aln": "MKALIFAAAGLLLLLPTFCQSGMENDTNNLAKPTLPIKTFRGAPPNSFEEFPFSALEGWTGATITVKIKCPEESASHLHVKNATMGYLTSSLSTKLIPAIYLLVFVVGVPANAVTLWMLFFRTRSICTTVFYTNLAIADFLFCVTLPFKIAYHLNGNNWVFGEVLCRATTVIFYGNMYCSILLLACISINRYLAIVHPFTYRGLPKHTYALVTCGLVWATVFLYMLPFFILKQEYYLVQPDITTCHDVHNTCESSSPFQLYYFISLAFFGFLIPFVLIIYCYAAIIRTLNAYDHRWLWYVKASLLILVIFTICFAPSNIILIIHHANYYYNNTDGLYFIYLIALCLGSLNSCLDPFLYFLMSKTRNHSTAYLTK-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QQR2-1", "uniprot_id": "F1QQR2_DANRE", "id": "F1QQR2-1", "name": "", "aln": "MRRVFVPLLLMLIFEDSLQDPASKYSRINTSNYPLNPKTFTG-----------------TIESNASQLSNSSQTQPVINVSANVINHTAGIISTRIIPFAYILAILIGIPSNVFVLACLSGK-KVLSSGILYFSLALSDLLLLFSLTFRVHYHLNNSDWIFGELACKLVTACFYGNIYCSIHAHMCISVMRYFAVVHPFLYRTMRKRFCAIWMSLTIWVVFSIAMAPEFVVQQSFHVSGQELVTCHDIQPYEEASYQALIPYRLSLICIGFVFPSLVIAFIYGSIIYHLNRSSQDWKRYIKASTLVFVIFLVCFAPCNLLLFAHYVKLYTQRQYELYAYYRVAVCLCSFHSCLDPFLSYLLTKTSTSQVKFRSFSSIPLKALSTI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: ::. :*:: :. :.. : * :: .* *:* * * : : : . ..:: . ::*. .:.: . :**::** *:* :::*:*:* ..* * : : :. ::: .**::*:*: .:*.*:: ****..:*:***: *: .*. ****:**:* *:.: **:* .*** *: : *: :: . :*. . : * * .:::*.::: ::.****: *:. : * :** :**::* ::* : * ::* *: .: * *:** *::*** :**** *::*. *:.: * :. ** * :*:** *::******* ::::*. ", "identical_positions": 102, "similar_positions": 135, "identity": "26.49%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110131-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZJG3-1", "uniprot_id": "D3ZJG3_RAT", "id": "D3ZJG3-1", "name": "Transmembrane prolyl 4-hydroxylase", "aln": "MAAAVATVQRPVAETIEEASNLQWPLPPEHRPSGAATRPGDGEEAPVRPLCKPRGICSRAYFLVLMVFVHLYLGNVLALLLFVHYSNGD---------ESTDPGPQRREQSPQPVPTLGP-------LTRLEGIKVGYERKVQVVAGRDHFIRTLSLKPLLFEIPGFLSDEECRLIIHLAQMKGLQRSQILPTEEYEEAMSAMRVSQLDLFQLLDQNHDGRLQLREVLAQTRLGNGRWMTPENIQEMYSAIKADPDGDGVLSLQEFSNMDLRDFHKYMRSHKAESSELVRNSHHTWLHQGEGAHHVMRAIRQRVLRLTRLSPEIVELSEPLQVVRYGEGGHYHAHVDSGPVYPETVCSHTKLVANESVPFETSCRYMTVLFYLNNVTGGGETVFPVADNRTYDEMSLIQDNVDLRDTRRHCDKGNLRVKPQQGTAVFWYNYLPDGQGWVGEVDDYSLHGGCLVTRGTKWIANNWINVDPSRARQALFQQEMARLAREGGADSQPEWALDRAYSDARAEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG58-1", "uniprot_id": "P4HTM_MOUSE", "id": "Q8BG58-1", "name": "Transmembrane prolyl 4-hydroxylase", "aln": "MAAAVATVQRPEAETVEEASNLQWPLPPEHRPSGAATRPGDSEDAPVRPLCKPRGICSRAYFLVLMVFVHLYLGNVLALLLFVHYSNGD---------ESTDPGPQRREQSPQPVPTLGP-------LTRLEGIKVGYERKVQVVAGRDHFIRTLSLKPLLFEIPGFLSDEECRLIIHLAQMKGLQRSQILPTEEYEEAMSAMQVSQLDLFQLLDQNHDGRLQLREVLAQTRLGNGRWMTPENIQEMYSAIKADPDGDGVLSLQEFSNMDLRDFHKYMRSHKAESNELVRNSHHTWLHQGEGAHHVMRAIRQRVLRLTRLSPEIVEFSEPLQVVRYGEGGHYHAHVDSGPVYPETICSHTKLVANESVPFETSCRYMTVLFYLNNVTGGGETVFPVADNRTYDEMSLIQDDVDLRDTRRHCDKGNLRVKPQQGTAVFWYNYLPDGQGWVGEVDDYSLHGGCLVTRGTKWIANNWINVDPSRARQALFQQEMARLAREGGMDSQPEWALDRAYSDARVEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NXG6-1", "uniprot_id": "P4HTM_HUMAN", "id": "Q9NXG6-1", "name": "Transmembrane prolyl 4-hydroxylase", "aln": "MAAAAVTGQRPETAAAEEASRPQW-APPDHCQAQAAAGLGDGEDAPVRPLCKPRGICSRAYFLVLMVFVHLYLGNVLALLLFVHYSNGD---------ESSDPGPQHRAQGPGPEPTLGP-------LTRLEGIKVGHERKVQLVTDRDHFIRTLSLKPLLFEIPGFLTDEECRLIIHLAQMKGLQRSQILPTEEYEEAMSTMQVSQLDLFRLLDQNRDGHLQLREVLAQTRLGNGWWMTPESIQEMYAAIKADPDGDGVLSLQEFSNMDLRDFHKYMRSHKAESSELVRNSHHTWLYQGEGAHHIMRAIRQRVLRLTRLSPEIVELSEPLQVVRYGEGGHYHAHVDSGPVYPETICSHTKLVANESVPFETSCRYMTVLFYLNNVTGGGETVFPVADNRTYDEMSLIQDDVDLRDTRRHCDKGNLRVKPQQGTAVFWYNYLPDGQGWVGDVDDYSLHGGCLVTRGTKWIANNWINVDPSRARQALFQQEMARLAREGGTDSQPEWALDRAYRDARVEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WG80-1", "uniprot_id": "X1WG80_DANRE", "id": "X1WG80-1", "name": "Transmembrane prolyl 4-hydroxylase", "aln": "MLSGKMMEPQ---DDIEEDDSPSASAPPSSSPSPSSSPPPRALPRQRTSLQKS-SVCSRSYFMVVMVFFHVYIINVIALLLYVHYNNGSNAISANRDFTSSDSSSHKVTGASDAQATADSGFPRNMFLPRIEGIRVGHVQKVSLVSGKVHEMKTLSLKPLLFEIPDFLSEEECAVVVRLAQLKGLMESQVMVPEGQEELDQQLNLSPEEIFNFLDLNQDGQLQPHEILTHSRVRDGIWLTSENLKEIYDGLKADLDGNGLLSLEEFGRLRSDAFQRFLLQRGVERSQLVRNSRHTWLYQGQGAHQVLQDLRKRVTLLTRLPSSLVELSEPLQVVRYEQGGHYHAHHDSGPVYPETACTHTRLAANTTSPFQTSCRYITVLFYLNNVQEGGETTFPVADNRTYEEASLIQNDVDLLDTRKHCDKGNLRVKPVKGTAVFWYNYLSDGRGWVGEQDEYSLHGGCVVTQGTKWVANNWINVDPDYQRQARYQLLVSQQESQ----EQEEPNSD-QHIEAHQDL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :. : ** . . **. : ::: . .* *. .:***:**:*:***.*:*: **:****:***.**. *:*...:: .. . .* .. *.*:***:**: :**.:*:.: * ::************.**::*** ::::***:*** .**:: .* ** . :.:* ::*.:** *:**:** :*:*:::*: :* *:*.*.::*:* .:*** **:*:***:**..: *:::: .: .* .:*****:****:**:***:::: :*:** ****...:**:********* :******* ********* *:**:*.** : **:*****:********* ****.*********:* ****::*** ***:*********** :**********.**:****: *:*******:**:****:*********. *** :* ::: : .* * * : :*: :*", "identical_positions": 255, "similar_positions": 146, "identity": "49.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110131-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TAF8-1", "uniprot_id": "LHPL5_HUMAN", "id": "Q8TAF8-1", "name": "LHFPL tetraspan subfamily member 5 protein", "aln": "MVKLLPAQEAAKIYHTNYVRNSRAVGVMWGTLTICFSVLVMALFIQPYWIGDSVNTPQAGYFGLFSYCVGNVLSSELICKGGPLDFSSIPSRAFKTAMFFVALGMFLIIGSIICFSLFFICNTATVYKICAWMQLAAATGLMIGCLVYPDGWDSSEVRRMCGEQTGKYTLGHCTIRWAFMLAILSIGDALILSFLAFVLGYRQDKLLPDDYKADGTEEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q4KL25-1", "uniprot_id": "LHPL5_MOUSE", "id": "Q4KL25-1", "name": "LHFPL tetraspan subfamily member 5 protein", "aln": "MVKLLPAQEAAKIYHTNYVRNSRAVGVMWGTLTICFSVLVMALFIQPYWIGDSVSTPQAGYFGLFSYCVGNVLSSELICKGGPLDFSSIPSRAFKTAMFFVALAMFLIIGSIICFSLFFVCNTATVYKICAWMQLAAATGLMIGCLVYPDGWDSSEVRRMCGEQTGKYTLGHCTIRWAFMLAILSIGDALILSFLAFVLGYRQDKLLPDDYKADGNEEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1Q837-1", "uniprot_id": "F1Q837_DANRE", "id": "F1Q837-1", "name": "", "aln": "MAKMLSAQEAAKIYHTNYVRNARAVGVLWTIFTICFAIIGMVVFIQPYWIGDSVDTPQSGYFGLFHYCIGNPITGELVCKGSALDFGSIPSGAFKTAMFFVGISLLLIVGTIVCFSLFFFCNSGSVYKICAWMQLAAATCMVIGCMIYPDGWDSEEVKRMCGQRTDKYTLGNCTVRWAYILAIISIMDSLTLSFLAFVLGNRQDKLLPEDFQEEKKEEA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*:*.***************:*****:* :****::: *.:***********.***:****** **:** ::.**:***..***.**** *********.:.::**:*:*:******.**:.:************** ::***::*******.**:****::*.*****:**:***::***:** *:* ********* *******:*:: : .**.", "identical_positions": 153, "similar_positions": 54, "identity": "69.86%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110131-9", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q08EC4-1", "uniprot_id": "CASS4_MOUSE", "id": "Q08EC4-1", "name": "Cas scaffolding protein family member 4", "aln": "MRGTSIREGAPKTLLARALYDNHADCSDELAFSRGDILTIVEQNVPESEGWWRCLLHGRQGLAPANRLQVLRETPADRPCPLLPRGPDTDLTSSGAPYQVQDLISPPPQGPVYEPMRSWVEGPSPATAQVYELPESPSSARIICEKTLSFPKQALSVLPRP----------TRASLPTLPSQVYDVPVQRQGFSTLERLEKQQFYDIPTSSQKALLHSSTSQ-----GRDVTLAPTMAFRQGGGYNPLSSPQKSERIHDTPVLLEKADVRNVSMTSFTKDSGSRAIPGSSAVHTG-----AVALSPQLGN--TVQRKNSLPEEPTYAFPTSRDPLPSDAGGSYKVPSRFLIPRVEQQNTMPNIYDTPKAMQGVSHNAPKAMQGVSLAGKELERGREAPENSP-----WISGQTSFLSPDSDRLSVASSDSRASVVSSCSSISMDSSSGSSSE-DSVKELWMDVDFAKETAVSLQHKVASSAAGLLLFVSRTWRFKDSLETNIHRIRRAADHVEESVREFLDFAQGVGGTACNLTDSYLQARIRDQLQTISSSYQTLLDAKGSLDRCNWSLEVLVTDKVQ-NSLDDLERFVATARIVPEDVKRFTSIVIANGKLLFKQNCEKGE-----------MDLKCERCIRPPQRETESYQESSPFDRQPTTEHSFELARKNRVNVCWQQSPNLQEKGKPTMEGKSNRNPDFHGMSPPPLTSPSPSGQNTERKIHLSKHSRLYFGALFKAISVFASSLSNGQPPEVFITQSKLVITVGQKLVDTLCSETQEKDERNEILCGSSHLCGLLKDLALATKSAVIQYPSPSALSLLQSEVERLEHHSRKFRDTLE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQ75-1", "uniprot_id": "CASS4_HUMAN", "id": "Q9NQ75-1", "name": "Cas scaffolding protein family member 4", "aln": "MKGTGIMDCAPKALLARALYDNCPDCSDELAFSRGDILTILEQHVPESEGWWKCLLHGRQGLAPANRLQILTEVAADRPCPPFLRGLEEAPASSEETYQVPTLPRPPTPGPVYEQMRSWAEGPQPPTAQVYEFPDPPTSARIICEKTLSFPKQAILTLPRP----------VRASLPTLPSQVYDVPTQHRGPVVLKEPEKQQLYDIPASPKKAGLHPPDSQAS---GQGVPLISVTTLRRGG-YSTLPNPQKSEWIYDTPVSPGKASVRNTPLTSFAEESRPHALPSSSSTFYNPPSGRSRSLTPQLNNNVPMQKKLSLPEIPSYGFLVPRGTFPLDEDVSYKVPSSFLIPRVEQQNTKPNIYDIPKATS-----------SVSQAGKELEKAKEVSENSAGHNSSWFSRRTTSPSPEPDRLSGSSSDSRASIVSSCSTTSTDDSSSSSSE-ESAKELSLDLDVAKETVMALQHKVVSSVAGLMLFVSRKWRFRDYLEANIDAIHRSTDHIEESVREFLDFARGVHGTACNLTDSNLQNRIRDQMQTISNSYRILLETKESLDNRNWPLEVLVTDSVQ-NSPDDLERFVMVARMLPEDIKRFASIVIANGRLLFKRNCEKEETVQ----LTPNAEFKCEKYIQPPQRETESHQKSTPSTKQREDEHSSELLKKNRANICGQ--------------------------NPGPLIPQPSSQQTPERKPRLSEHCRLYFGALFKAISAFHGSLSSSQP-AEIITQSKLVIMVGQKLVDTLCMETQERDVRNEILRGSSHLCSLLKDVALATKNAVLTYPSPAALGHLQAEAEKLEQHTRQFRGTLG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5S9-1", "uniprot_id": "A0ACD6B5S9_DANRE", "id": "A0ACD6B5S9-1", "name": "", "aln": "----------METLFARALYANTAETEDELAFCKGEIILVLEKNVVGSTGWWKCALRGRQGLAPANRLAPLSPAEAEQIAAERDCSTNHSHQS---IYQTPIALSKSPETPIYEDMNTIYKVP-PQGVCSPNKQEDPEGTRPLHDGLSAHPKTGADIYDVPNLLRKSCLFTASPLHPSETSLMSSAEFHSRNEATNMLQMLQNVRCETATNHKATTLPPFGTQDPNYDFPVPSITEDSKKPRCGYSTMPNPCKSEWIYDVPVFPQKQGCEPG----YCDTLPPKDIDSTTALYDILP-----ARIWPEKKHCPIQPLYDVPKPSISLTQSCTVNEYSPISSIYDVPPCFRQTKTTAEQPRKQSPPEMDSKNG-----QEPLEYRGKPGPLYDQLHRWPSRGRTPFRQPLESTVRRDNEGTRDHQRSSTVSTSSTASSSSRSSCDSFMLSSPEPEPLREITLSQEEAGNKLLELKEAVCQSVPKLMLFVSSQWRSREHLGQHLDQIRTASEDVTDSIDSFLNFTLDVRGNAQRLTDSNLQTRLLKQLSIVEDSGLILQQAASALRDQGWHLDVLAQDAGHSQMPDHLERFVMVARTVPEDVKRLVSMLNANGKLLFRVQVKELEVMENEGSSEGTNHKKCEPMVDSGIDESDYVQLQTTAEIEQEPKPTKSSIKSKRNSDSLKK------------------------QVSKPQSGSPCNPIQTSRKCPISDHCRLYFGAIQKAISVFISSLNENKPPEQFISHSKLVIMVGQRLVNTLCREAKSREAGEEMLSMSNQLCAQLKQLALVTKKAALNFPDKLAVQEAHDIAKELAQRAQHFRTSLDV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*:***** * .: .*****.:*:*: ::*::* * ***:* *:*********** * . *:: .. . : * **. .. *:** *.: : * * . : : * .:* : : :.** . * . . *: .* : .. : :. . *:. .:: :** .. . . *. . : : *..:..* *** *:*.** * . . : . .: : .::: . : : .:* .:*: . . *.**. * .:. ::. : .: . . .* :: :. .... :. . . . . :*: * :* .**.* * *. **.* :. :*: :. : * :. : *:. * .*.. *:**** ** :: * ::. *: :::.: :*: .**:*: .* *.* .**** ** *: .*:. :..* * :: :* .* *:**. * : : *.***** .** :***:**:.*:: ***:***: : :: * . *** : . *:: * .:. : : : . :.:* . . : . * . . ..** :*.*.******: ****.* .**...:* :*::***** ***:**:*** *::.:: :*:* *.:**. **::**.**.*.: :*. *: : .:.* :::::** :* ", "identical_positions": 199, "similar_positions": 258, "identity": "23.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110201-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AJW4-1", "uniprot_id": "A2AJW4_MOUSE", "id": "A2AJW4-1", "name": "Protein phosphatase 1 regulatory subunit", "aln": "MSKGS--GSAPLPSTPGSRKLV-PRSLSCLSDMDR------RPCRPPG--------------CDPRLRPIIQRRSRSLPTS-PERRAKAAGAPGAACGAGCNRQVRVRFADALGLELAQVKVFNAGDDPSVPLHVLSRLAINSDLCCSSQDLEFTLQCLVPDFSP--PIETPGFGERLARQLVCLERVTCSDLGISGTVRVRNVAFEKQVTVRYTFSGWRSAHEAVARWRGPAG-AEGTEDIFAFGFPVPPFLLELGSQVHFALRYGVAGAEYWDNNDGRDYSLTCRSHALHMPRGECEESWIHFI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95685-1", "uniprot_id": "PPR3D_HUMAN", "id": "O95685-1", "name": "Protein phosphatase 1 regulatory subunit 3D", "aln": "MSRGP--SSAVLPSALGSRKLG-PRSLSCLSDLDGGVALEPRACRPPGSPGRAPPPTPAPSGCDPRLRPIILRRARSLPSS-PERRQKAAGAPGAACRPGCSQKLRVRFADALGLELAQVKVFNAGDDPSVPLHVLSRLAINSDLCCSSQDLEFTLHCLVPDFPP--PVEAADFGERLQRQLVCLERVTCSDLGISGTVRVCNVAFEKQVAVRYTFSGWRSTHEAVARWRGPAG-PEGTEDVFTFGFPVPPFLLELGSRVHFAVRYQVAGAEYWDNNDHRDYSLTCRNHALHMPRGECEESWIHFI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WFN1-1", "uniprot_id": "X1WFN1_DANRE", "id": "X1WFN1-1", "name": "", "aln": "MESHPYVSGPALQLTSAFGELSKPNKTFHLRNIYNP---KPPPQRPPVAIR---PPSPKAGSVPPPQDAVIRRRLSCEPEPKPIMRRRAKSLSSSSDRQTC-RNIQVRFVDSLGLQLEDVKFFKSSEDPLVPVHVITRLLASSELASK-KNLELSLPYFQPSFPDNMTTDVSAFSRRLCRQRVCLEQVFCSELGITGTAQVLNLCFQKEVIVRYSFTDWRSSADCRAGWVCSVRRGDLESDVFRFLLPVPPFIMQPGAVLQFAICFRVPGSEFWDNNDGCNYKLTCQTYKLTVPR-ECEDSLVHFI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . ... * : . :* *.. * :: . *** * .:* ** . * . * * :* . ..:: * ::::***.*:***:* :**.*::.:** **:**::** .*:*... ::**::* : *.*. . :.. *..** ** ****:* **:***:**.:* *:.*:*:* ***:*:.***: :. * * .. : .*:* * :*****::: *: ::**: : *.*:*:***** :*.***:.: * :** ***:* :***", "identical_positions": 107, "similar_positions": 97, "identity": "34.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110201-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9C0K0-1", "uniprot_id": "BC11B_HUMAN", "id": "Q9C0K0-1", "name": "B-cell lymphoma/leukemia 11B", "aln": "MSRRKQGNPQHLS--QRELITPEADHVEAAILEEDEGLEIEEPSGLGLMVGGPDPDLLTCGQCQMNFPLGDILVFIEHKRKQCGGSLGACYDKALDKD---SPPP-SSRSELRKVSEPVEIGIQVTP-DEDDHLLSPTKGICPKQENIAGPCRPAQLPAVAPIAASS-HPHSSVITSPLRALGALPPCLPLPCCSARPVSGDGTQGEGQTEAPFGCQCQLSGKDEPSSYICTTCKQPFNSAWFLLQHAQNTHGFRIYLEPGPASSSLTPRLTIPPPLGPEAVAQSPLMNFLGD-SNPFNLLRMTGPILRDHP-GFGEGRLPGTPPLFSPPPRHHLDPHRLSAEEMGLVAQHPSAFDRVMRLNPMAIDSPAMDFSRRLRELAGNSS---TPPPVSPGRGNPMHRLLNP--FQPSPKS-PFLSTPPLPP-MPPGG--TPPPQPPAKSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTHMHKAGSLAGRSDDGLSAASSPEPGTSELAGEGLKAADGDFRHHESDPSLGHEPEEEDEEEEEEEEELLLENESRPESSFSMDSELSRNRENGGGGVPGVPGAGGGAAKALADEKALVLGKVMENVGLGALPQYGELLADKQKRGAFLKRAAGGGDAGDDDDAGGCGDAGAGGAVNGRGGGFAPGTEPFPGLFPRKPAPLPSPGLN----SAAKRIKVEKDLELPPAALIPSENVYSQWLVGYAASRHFMKDPFLGFTDARQSPFATSSEHSS-ENGSLRFSTPPGDLLDGG-LSGRSGTASGGSTPHLGGPGPGRP-SSKEGRRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQIGKEVYRCDICQMPFSVYSTLEKHMKKWHGEHLLTNDVKIEQAERS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99PV8-1", "uniprot_id": "BC11B_MOUSE", "id": "Q99PV8-1", "name": "B-cell lymphoma/leukemia 11B", "aln": "MSRRKQGNPQHLS--QRELITPEADHVEATILEEDEGLEIEEPSSLGLMVGGPDPDLLTCGQCQMNFPLGDILVFIEHKKKQCGG-LGPCYDKVLDKS---SPPP-SSRSELRRVSEPVEIGIQVTP-DEDDHLLSPTKGICPKQENIAGPCRPAQLPSMAPIAASSSHPPTSVITSPLRALGVLPPCFPLPCCGARPISGDGTQGEGQMEAPFGCQCELSGKDEPSSYICTTCKQPFNSAWFLLQHAQNTHGFRIYLEPGPASTSLTPRLTIPPPLGPETVAQSPLMNFLGD-SNPFNLLRMTGPILRDHP-GFGEGRLPGTPPLFSPPPRHHLDPHRLSAEEMGLVAQHPSAFDRVMRLNPMAIDSPAMDFSRRLRELAGNSS---TPPPVSPGRGNPMHRLLNP--FQPSPKS-PFLSTPPLPP-MPAG---TPPPQPPAKSKSCEFCGKTFKFQSNLIVHRRSHTGEKPYKCQLCDHACSQASKLKRHMKTHMHKAGSLAGRSDDGLSAASSPEPGTSELPGD-LKAADGDFRHHESDPSLGPEPED-DEDEEEEEEELLLENESRPESSFSMDSELGRGRENGGGVPPGVAGAG-AAAAALADEKALALGKVMEDAGLGALPQYGE------KRGAFLKRAGDTGDAG----AVGCGDAGAPGAVNGRGGAFAPGAEPFPALFPRKPAPLPSPGLGGPALHAAKRIKVEKDLELPPAALIPSENVYSQWLVGYAASRHFMKDPFLGFTDARQSPFATSSEHSS-ENGSLRFSTPPGDLLDGG-LSGRSGTASGGSTPHLGGPGPGRP-SSKEGRRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCELCNYACAQSSKLTRHMKTHGQIGKEVYRCDICQMPFSVYSTLEKHMKKWHGEHLLTNDVKIEQAERS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2R8QLP7-1", "uniprot_id": "A0A2R8QLP7_DANRE", "id": "A0A2R8QLP7-1", "name": "", "aln": "MSRRKQGNPQHLSLTQRENLPTPADHDAGMNQCPSEG-SVSSPAG-----GAGESDLLTCGQCQTNFPLGDILVFIEHKRRLCPG-PSSCFDKPSDCGGSGSPSPRPLRPDVCRRSGPVEVGIQVSPREEEEKRLTPARGICPKQEGVP-----------------------------------------------------------------------TGKDEPSSYICTTCKQPFTSAWFLLQHAQNTHGIRIYLDTHPTSCSLTPRMALPPPLGADALPRSPLASFLGDGSNPFQLLRMGAPLLREPPHGYIETRLPSTPPFVSPPPPRHP-LERLGPEEMGLLSQHPSAFERVMRMTPMGIHEPSMGFSQRLRELAGNNNNGGPTPPLSPNRVPPMHRLLSPTLFQHGSKALPFLPTPSQPPSIPSRGNSSSPLNQVGKAKSCEFCGKTFKFQSNLIVHRRSHTGERPYKCHLCDHACSQASKLKRHMKTHMHKSGSMG----------SSPEQGGQDSAGEGLKSCEDNGTREGID---NEEEEDDEEEEEEEEEEEEQQNGSRPDSNLSMDSELSRNRENGPRTTP--------------EDKPLATDRVTES-------QYNN-----LDNHLRLPPGSRPCEGMDRDSQAREIDRDRQPMVNGRG--CGP-EDSISAMFHRKPMPISSSSLSG---SSAKRIKVEKDVELPQVPVISPENVYSQLLAGYAASRHFIREPFLGFNDSRQSPFGTPSEHSSSETGSLRFSTPPGEILEGGGMSGRSDSST--PHLHLRGPGPGRPPSSKESRRSDTCEYCGKVFKNCSNLTVHRRSHTGERPYKCDLCSYACAQSSKLTRHMKTHGQFGKEVYRCDICHMPFSVYSTLEKHVKKWHGEHLLTSEVKLEQADRA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************* *** :.. *** . .** .:..*:. *. :.********* **************:: * * ..*:** * . **.* . *.:: : * ***:****:* :*::: *:*::*******.:. :*****************.**************:****:. *:* *****:::*****.:::.:*** .**** ****:**** .*:**: * *: * ***.***:.**** :* .**..*****::******:****:.**.*..*:*.**:********.. ..**:**.* ******.* ** ..*: ***.**. ** :*. :.* : .*:**************************:****:**********************:**:. **** * .: .*: **:.:.: :. * . * *: :*:******* :* ***:*.:******.*.**** * ::*.*. .:* *. **.: .. * .. :. * . ***** .* :.:..:* *** *:.*..*. :*********:*** ..:*..****** *.********:::*****.*:*****.*.***** *.**********::*:** :****.::: . ** ******* ****.**********************************:**.******************:**********:************:**********.:**:***:*:", "identical_positions": 490, "similar_positions": 186, "identity": "53.26%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110203-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZUX2-1", "uniprot_id": "D3ZUX2_RAT", "id": "D3ZUX2-1", "name": "Glycosyltransferase 1 domain-containing protein 1", "aln": "MRLLFLAVLRPHTGNAVTAGRLRDHLEAAGHMCVLRDAFDFESPSEIANLIVGEN-LEAALALHLYRGGRLLQGHGIPFGVIFGGTDLNEDANHKEKKEVMGKVLEEARFAVAFTEAMKDTAEVQWPHATGKIFVQSQGIATIPNADFNWNTFLQQS-EIDQSADDLHIFLVICGLRPVKDPLYLVDAFSEWHQETPNVYMVIVGPEVDPVFTREVKDRVRRASGVRLIREMCQEDLHAVVKSCFALVNSSVSEGMSAAILEAMDLEVPVLARNIPGNSAVVEHGVTGLLFSNPQEFIQLAKRLVSDPALEKEIVTNGREYVRTHHSWQVERDTYQRLIGKLEACSED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A4FUP9-1", "uniprot_id": "GL1D1_MOUSE", "id": "A4FUP9-1", "name": "Glycosyltransferase 1 domain-containing protein 1", "aln": "MRLLFLAVLRPHTGNAVTAGRLRDHLEAAGHMCVLRDAFDFESPSEIANLIMDEN-LEAALALHLYRGGRLLQGHSIPFGVIFGGTDLNEDANHKEKKEVMGKVLEEARFAVAFTEAMKDTAQVQWPHATGKIFVQSQGIATIPNANFNWNTFLQQS-EIDQSADNLYIFLIICGLRPVKDPLYLVDAFSEWHQETPNVYMVIVGPEVDPVFTREVKERVRRAAGVRLIREMCQEDLHAVVKSCFALVNSSVSEGMSAAILEAMDLEVPVLARNIPGNSAVVEHGVTGLLFSNPQEFIQLAKRLVSDPALEKEIVTNGREYVRTHHSWQVERDTYQRLIRKLETNLED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96MS3-1", "uniprot_id": "GL1D1_HUMAN", "id": "Q96MS3-1", "name": "Glycosyltransferase 1 domain-containing protein 1", "aln": "MRLLFLAVLRPHTGNAVTAQRVRAHLEAAGHVCVLKDAFDFESRSEIANLILAEN-CEAALALHLYRGGRLLQGHRIPFGVIFGGTDVNEDANQAEKNTVMGRVLEEARFAVAFTESMKEMAQAQWPHAKGKVYVQSQGIATTPNAAFNWNTFLQRS-EINQSADNLHIFLLICGLRQVKDPLYLVDAFSAWHQEEPNVHLVIVGPEVDPVFTREVKAKVKRAAGVRLIGEMPQEDLHAVVKNCFAVVNSSVSEGMSAAILEAMDLEVPVLARNIPGNAAVVKHEVTGLLFSNPQEFVHLAKRLVSDPALEKEIVVNGREYVRMYHSWQVERDTYQQLIRKLEGSTED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BEP1-1", "uniprot_id": "A0A8M2BEP1_DANRE", "id": "A0A8M2BEP1-1", "name": "", "aln": "MRVLFLAYLSPKTGNCTTAERIRNHIEAAGHTCVLCDTRGLSSASDVSSLMTQEPRFEAALAIHLFKGGRLLLDVGLPFGVVFGGTDVNEDVRDEHKRAVMEEVLRKARFAVAFTDALKEQAEMLLVCESKKIHVQPQGIETRVASNFSWSDFLHNTGVCSKQVENLQVFLLVCGLRRVKDPLYLVEAFSEWHSQNPLVILIIIGPKMDPVFTAEVEESVKRFVGVFLADDLSQEELHAAMQKSFALVNSSLSEGMSAAILEAMDLGLPVLARDVPGNAAIVEHQVTGLLYSSPQEFISMSQKLLDDKELRKRLVRNGKNYITTCHNPMKERTTYQELLKKLH-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:**** * *:***..** *:* *:***** *** *: .:.* *:::.*: * *****:**::***** . :****:*****:***... .*. ** .**.:********:::*: *: . *:.**.*** * : *.*. **:.: .:..::* :**::**** ********:*** **.: * * ::*:**::***** **: *:* ** * :: **:***.::..**:****:************** :*****::***:*:*:* *****:*.****: ::::*:.* *.*.:* **::*: *. ** ***.*: **. ", "identical_positions": 179, "similar_positions": 99, "identity": "51.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110203-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZ51-1", "uniprot_id": "D3ZZ51_RAT", "id": "D3ZZ51-1", "name": "", "aln": "MSDRLGQITQGKDGKSKYSTLSLFDKYKGRSVGAVRSSVIPRHGLQSLGKVATARRMPPPANLPSLKSENKGNDPNIVIVPKDGTGWANKQDQQDPKSSSVTASQLPESQPQPGLQKSVSNLQKPTQSISQENTSSVPGGPKSWAQLSGKPVGHEGGLRGSSRLLSFSPEEFPTLKAAGGQDKAGKEKGALDLSYGPGPSLRPQNVSSWREGGGRNIISAVSLSASPTELGSRNS-------------------------SGGDGASSSACTSDSKDPSLRPAQPSRKGAS--QFMGHVYQPPTYHDMLPAFMCSPQSSENQNTVERSSFPLPQLRLEPRVPFR-----QFQMNDQDGKE-RPGVARP---VRPLRQLVERAPRPTIINAENLKGLDDLDTDADDGWAGLHEEVDYSEKLKFSDDEDEEDVVKDGRSKWNNWDPRRQRALSLSSADSTDAKRTQEEGKDWSGTAGVSRVVRKVPEPQPPSRKLHSWASGPDYQKPTMGSMFRPQSIEDKEDKPPPRQKFIQSEMSEAVERARKRREEEERRAREERLAACAAKLKQLDQKCRQAQKASETPKPVEKEVPRSPGIEKLSPPENGPVVRKGSPEFPVQEAPTMFLEETPATSPTVAQSNNSSSSSSSS-IEEEVREAGSPAQEFSKYQKSLPPRFQRQQQQQQQQQQQQQQQQQQQQQQQQEQLYKMQHWQ----PVYPPPSHPQRTFYPHHPQMLGFDPRWMMMPSYMDPRITPTRTPVDFYPSALHPSGLMKPMMPQESLSGTGCRSEDQNCVPSLQ-ERKVTAIDPAPVWSPEGYMALQ--NKGYSLSHPKSADTLAMGMHVRNERSYCASPGRSGGISAQRDLFEERGEEFLSAFDKKAQADFDSCISSQRIGQELLFPPQENVQEVGAPGGCTPNLRCSPLEPDFVPAEKKPECGSWDVGHQPKAADMANSVELEAPRQEPSFHVSSWEKEGSPKKQPNPEPEWTPEPRSSSGQQQEQPGRTRRSGPIKKPVLKALKVEEKEKALERVRQGLGEESSQRATEKEPPCRAEEDEDEENNPALA-NASSALEDKAAARGGFGHEASKLDEEAKTDKTWESRPS--REASEIPPPKRNNWIFIDEEQAFGGRAQARSRGRGFREFTFRGGRPTSSSTSGLCGTGVLGSRGMYSGGQRSNRGRGLRDFPPPEDCPRAKPRRRIASETHSEGSEYEELPKRRRQRGSEPSHEGMLTERDEGALK-----DSWRSNRTYTEDQGSLDARSRGPRTCGRALPPRLSNCSYGRRTFVAKEPPHWQSRSPGNSWQEYGSSDPCGPRRATDRDYIPDSYRHSDTFGSRLFEDSRTEDKKSFFQDDHGADSEGAENRPFRRRRPPRQDKPPRFRRLRQERESLGLWGPEEESH-LLASQWPGRSKLCPGDKSGPGGHRSPELSYQNSSDHANEEWETASESSDFSERRERREGLAAEPEAQGDGGLSGASLGEKKELAKRSFSSQRPLADRQSRKLEPGGFGEKPVRPGGGETSPRCESQQSGTPLKVKRSPDEALPGGLG------SHSPYALERTTHGSSDGSETTSKKTEKEVSLAAQRAGEQEEARKQFDLGYGNAIIDNCGSSPGEENEVGSMVGEGFIEVLTKKQRRLLEEERRKKEQAAQV--KGRGLSSRIPPRFAKKQNGLCLEQGDVAVPGSSLGTEIWESSSQALPVQGAASDSWRTAVTAFSSAEPGTSEQGFKSSQGDSGVDLSAESRESSATSSQRSSPYGTLKPDEMSGPGLAESKADSHKDQAQKQSEHKDSEQGSGQSKEHRPGPIGNERSLKNRKGSEGAERLQGAVVPPVNGVEIHVDSVLPVPPIEFGVSPKDSDFSLPPGSVSGPVGNPVAKLQDVLASNAGLTQSIPILRRDHHIQRAIGLSPMSFPTADLTLKMESARKAWENSPSLPEQNSPGGAGSGIQPPSSVGASNGVNYSSFGGVSIPPMPVASVAPSASMPGSHLPPLYLDGHVFASQPRLVPQTIPQQQSYQQAATAQQIPISLHTSLQAQAQLGLRGGLPASQSQEIFSSLQPFRSQVYMHPSLSPPSTMILSGGTALKPPYSAFPGIQPLEMVKPQSGSPYQPMSGNQALVYEGQLGQAAGLGASQMLDSQLPQLTMPLP----RYGSGQQPLILPQSIQLPPGQSLSVGAPRRIPPPGSQPPVLNTSRESTQMELKGFHFADNKQNVSTGGSAPSPQAYRPSSASPSGKPSGSAVNMGSVQGHYVQQAKR---------------------------------VDEKPSLGTVK--------------------------LQEASSATSQMKRTGAIKPRAVKVEGSKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TPM1-1", "uniprot_id": "PRC2B_MOUSE", "id": "Q7TPM1-1", "name": "Protein PRRC2B", "aln": "MSDRLGQITQGKDGKSKYSTLSLFDKYKGRSVGAVRSSVIPRHGLQSLGKVATARRMPPPANLPSLKSENKGNDPNIVIVPKDGTGWANKQDQQDPKSSSVTASQPPESQPQPGLQKSVSNLQKPTQSISQENTNSVPGGPKSWAQLSGKPVGHEGGLRGSSRLLSFSPEEFPTLKAAGGQDKAGKEKGALDLSYGPGPSLRPQNVTSWREGGGRNIISAASLSASPTELGSRNA-------------------------SGADGAPSLACTSDSKEPSLRPAQPSRRGAS--QFMGHGYQPPTYHDMLPAFMCSPQSSENQTTVERSSFPLPQLRLEPRVPFR-----QFQMNDQDGKE-RPGVARP---VRPLRQLVERAPRPTIINAENLKGLDDLDTDADDGWAGLHEEVDYSEKLKFSDDEDEEDVVKDGRSKWNNWDPRRQRALSLSSADSTDAKRTQEEGKDWSGTAGGSRVIRKVPEPQPPSRKLHSWASGPDYQKPTMGSMFRQHSAEDKEDKPPPRQKFIQSEMSEAVERARKRREEEERRAREERLAACAAKLKQLDQKCRQAQKANETPKPVEKEVPRSPGIEKVSPPENGPVVRKGSPEFPVQEAPTMFLEETPATSPTVAQSNSSSSSSSSSSIEEEVRESGSPAQEFSKYQKSLPPRFQRQQQQQQQ---------QQQQQQQQEQLYKMQHWQ----PVYPPPSHPQRTFYPHHPQMLGFDPRWMMMPSYMDPRITPTRTPVDFYPSALHPSGLMKPMMPQESLSGTGCRSEDQNCVPSLQ-ERKVTALDPAPVWSPEGYMALQ--NKGYSLPHPKSADTLAMGMHVR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPDEALPGGLG------SHSPYALERTTHASSDGPETPSKKSEREVSLPTQRASEQEEARKQFDLGYGNALIDNCASSPGEENEASSVVGEGFIEVLTKKQRRLLEEERRKKEQAAQVPVKGRGLSSRIPPRFAKKQNGLCLEQ-DVTVPGSSLGTEIWENSSQALPVQGAASDSWRTAVTAFSSTEPGTSEQGFKSSQGDSGVDLSAESRESSATSSQRSSPYGTLKPEEISGPGLAESKADSHKDQAQKQAEHKDSEQGSAQSKEHRPGPIGNERSLKNRKGSEGAERLPGAVVPPVNGVEIHVDSVLPVPPIEFGVSPKDSDFSLPPGSVSGPVGNPVAKLQDVLASNAGLTQSIPILRRDHHMQRAIGLSPMSFPTADLTLKMESARKAWENSPSLPEQSSPGGAGSGIQPPSSVGASNGVNYSSFGGVSMPPMPVASVAPSASIPGSHLPPLYLDGHVFASQPRLVPQTIPQQQSYQQAATAQQIPISLHTSLQAQAQLGLRGGLPVSQSQEIFSSLQPFRSQVYMHPSLSPPSTMILSGGTALKPPYSAFPGIQPLEMVKPQSGSPYQPMSGNQALVYEGQLGQAAGLGTSQMLDSQLPQLTMPLP----RYGSGQQPLILPQSIQLPPGQSLSVGAPRRVPPPGSQPPVLNTSRESAPMELKGFHFADSKQNVPTGGSAPSPQAYR-----------------------------------------------------------------------------------------------------------QSEWMKNPAWEP----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JSZ5-1", "uniprot_id": "PRC2B_HUMAN", "id": "Q5JSZ5-1", "name": "Protein PRRC2B", "aln": "MSDRLGQITKGKDGKSKYSTLSLFDKYKGKSVDAIRSSVIPRHGLQSLGKVAAARRMPPPANLPSLKSENKGNDPNIVIVPKDGTGWANKQDQQDPKSSSATASQPPESLPQPGLQKSVSNLQKPTQSISQENTNSVPGGPKSWAQLNGKPVGHEGGLRGSSRLLSFSPEEFPTLKAAGGQDKAGKEKGVLDLSYGPGPSLRPQNVTSWREGGGRHIISATSLSTSPTELGSRNS-------------------------STGDGAPSSACTSDSKDPSLRPAQPVRKGAS--QFMGNVYHPPTYHDMLPAFMCSPKSSENQGTVERGSFPLPQLRLEPRVPFR-----QFQMNDQDGKENRLGLSRP---LRPLRQLVERAPRPTIINAENLKGLDDLDADADDGWAGLHEEVDYSEKLKFSDDEEEEEVVKDGRPKWNSWDPRRQRQLSMSSADSADAKRTREEGKDWAEAVGASRVVRKAPDPQPPPRKLHGWAPGPDYQKSSMGSMFRQQSIEDKEDKPPPRQKFIQSEMSEAVERARKRREEEERRAREERLAACAAKLKQLDQKCKQARKAGEARKQAEKEVPWSPSAEKASPQENGPAVHKGSPEFPAQETPTTFPEEAPTVSPAVAQSNSS---------EEEAREAGSPAQEF-KYQKSLPPRFQRQQQQQQQ-----------------EQLYKMQHWQ----PVYPPPSHPQRTFYPHHPQMLGFDPRWMMMPSYMDPRITPTRTPVDFYPSALHPSGLMKPMMPQESLNGTGCRSEDQNCVPPLQ-ERKVTPIDSPPVWSPEGYMALQ--SKGYPLPHPKSSDTLAMDMRVRNESSFSASLGRAGGVSAQRDLFEERGEEYLSAFDKKAQADFDSCISSQRIGQELLFPPQENVQDAGAPGGHTQNLRCSPLEPDFVPDEKKPECGSWDVSHQPETADTAHGVERETPREGTAFNISSWDKNGSPNKQPSSEPEWTPEPRSSSSQHPEQTGRTRRSGPIKKPVLKALKVEDKEKELEKIKQELGEESTRLAKEKEQSPTAEKDEDEENDASLANSSTTTLEDKGPGHATFGREATKFEEEEKPDKAWEARPP--RESSDVPPMKRNNWIFIDEEQAFGVRGQARGRGRGFREFTFRG-RPAGGNGSGLCGGGVLGARSIYCSSQRSGRGRGLREFARPEDCPRAKPRRRVASETHSEGSEYEELPKRRRQRGSENGNEGSLLEREESTLKKGDCRDSWRSNKGCSEDHSGLDAKSRGPRAFGRALPPRLSNCGYGRRTFVSKESPHWQSKSPGSSWQEYGPSDTCGSRRPTDRDYVPDSYRHPDAFGGRGFEDSRAEDKRSFFQDEHVADSENAENRPFRRRRPPRQDKPPRFRRLRQERESLGLWGPEEEPH-LLAGQWPGRPKLCSGDKSGTVGRRSPELSYQNSSDHANEEWETASESSDFSERRERREGPGSEPDSQVDGGLSGASLGEKKELAKRSFSSQRPVVDRQSRKLEPGGFGEKPVRPGGGDTSPRYESQQNGTPLKVKRSPDEALPGGLSGCSSGSGHSPYALERAAHASADLPEASSKKAEKEAKLAAPRAGEQGEAMKQFDLNYGSAIIENCGSSPGEESEVGSMVGEGFIEVLTKKQRRLLEEERRKKEQAVQVPVKGRGLSSRIPPRFAKKQNNLCLEQGDVTVPGSSLGTEIWESSSQALPVQAPANDSWRKAVTAFSSTETGSAEQGFKSSQGDSGVDLSAESRESSATSSQRSSPYGTLKPEEMSGPGLAEPKADSHKEQAPKPSEQKDSEQGSGQSKEHRPGPIGNERSLKNRKGSEGAERLQGAVVPPVNGVEIHVDSVLPVPPIEFGVSPKDSDFSLPPGSASGPTGSPVVKLQDALASNAGLTQSIPILRRDHHIQRAIGLSPMSFPTADLTLKMESARKAWENSPSLPEQSSPGGAGSGIQPPSSVGASSGVNYSSFGGVSMPPMPVASVAPSASMPGSHLPPLYLDGHVFASQPRLVPQTIPQQQSYQQAAAAQQIPISLHTSLQAQAQLGLRGGLPVSQSQEIFSSLQPFRSQVYMHPSLSPPSTMILSGGTALKPPYSAFPGMQPLEMVKPQSGSPYQPMSGNQALVYEGQLSQAAGLGASQMLDSQLPQLTMPLP----RYGSGQQPLILPQSIQLPPGQSLSVGAPRRIPPPGSQPPVLNTSREPSQMEMKGFHFADSKQNVPSGGPVPSPQTYRPSSASPSGKPSGSAVNMGSVQGHYVQQAKQR--------------------------------VDEKPSLGAVK--------------------------LQEAPSAASQMKRTGAIKPRAVKVEESKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BJD6-1", "uniprot_id": "A0A8M2BJD6_DANRE", "id": "A0A8M2BJD6-1", "name": "", "aln": "MSDRLGQITKSKDGKSKYSSLSLFDKYKGKSIETQKTTVVARHGLQSLGKVAAARRMPPPAHLPSLKSESKGNDPNVIIVPKDGTGWANKQDQPDPKSSVASSAQLPEPQPPLALQKSVSNLQKPMPITSPESTS--TGGPKQWAQLNGKAVDQDG-LKVSSRLQPFSHEDFPTLKAAGEQDKVGKERSVFDPSYGPGPSLRPQNVSSWREGGGRNLQPPSLSSAPPGDTDTKSSGSVEAPLPPPPSTSTSTSSSASPAASSSSTAAAAAPSSEVKEPSLRPAPPLTRRAAPPALQYQHHTTTTYHDMLPAFMCPKETREAPGSSDGPAAVVAPVRFDSRPIFRPPFPAPEPVNGDVRREPRFPRAPPRPSSRPIRRPGDRAPRPAIINPDDLKDLDELDNDCEDGWAGLHEEVDYSEKLKFSDDE-EDHAPREKSKIWDDWDHHHHHHHLQGQHSSQSSG----DGAFPQEPEDEPYLRQQEP---PASRKTSTRFPAEPQQKASVNSESAEE-QDEPQRSAPPRGKFVSADVS-AVERARRRREEEERRAREERLAACAEKLKKLDEKFGKTEKPARSGEADGKELAQSPARRSAKPQQDG--WQYGSKEVTDTPAESASSQDYKDEGCNFHNNDDE---------DDDGGESTSPVPEYSRHQKPVPPRFQKQQQQQEQ-------------------VYKLASWQQSAHPAQPSSAHPQRGFYP--PHVLGFDPRWMMMPPYMDPRLAQGCSPVDYYPPGVHSSGLVKPVIQPDHLNSPGSTS-DEGCHPSMHQERRAPSTEPYQVWNQDSYPSARSFTPPYQRTHENGERAPADDRSDRS-------------TSRHDSYEEHRHERTDSPAEETTHQGFRQGRVSDGSQREPMMLSR------------THDDAQHQKEEPYDSKEKSYEADFWRRDVRKESSGQ-----------------TQWSDHGSSSSSSISQPSETSG------------RTLRRTGPIKKPVLKPLKVEDKENEKPKAEPEEKPVPYRLEKEVITN-----VYDLKKDAPHVSNRHSSSVEDKQADALKMEKTSALSEELHKESCWEKSQSDCSDSRDPTAPRRNNWIFIDEEQAFAG-ARGRGRGRGFREFNSRGGGARGGRSD--TNRGAYNNNNNNTGAQRLTRGRGNRVFRG-DDLQRGKPRRRNVSETHSETSEYEEQPKRPRQKVSENGGEASGEVKKADR-------ESWRSNKVYTDDQS----EKPKSRVFGRSFPPRLN-AAYNRGFTGTRDISTWRGR--GTQFGSSSSQENGYNFVADSYSKRTEPLKYPAKFTGTFAENGVEDRDGGYYVDD------NPDNRPLRRRRPPRQDKPPRFRRLRQERDGAGAWSNDDYVNGEFPNQWPSRAKSAEEHWQNHYPGGRSQ-SQEMTAQSQGEDWETGSDNSDFGDWREKRGPHG----DPLTDAALGDPGSEKRELSKRSFSSQRPLDRQNRKNDVSVMENSKMGRP--ADAGSRNDSWQNGVASGSKRSPEESVS-GLS------SASVYGVEQNEDRST--PEPTGKIIEKELKPRNMKA-DMTEPLSQYDLNTYSIESDSGASVPSPE---------VFQDSLSKKQRRPQEDERRRKEQGPPSSVKSRTIASKMPPRFAKKQGSMSMEQPEETLTANNLGTEIWETNSTALTVQSSGGDSWTKQVS-YTGSEPNS-----------------------------------------------------------------EDSDAGPEQSKEHKPGPIGNERSLKNRKGSEGLERLEGSITP-VNGVDIHVENVIPVPPIEFGVNAKDSDFSLPAGSAAVPVSNPVSKLQDALAGNAGLTQAIPMLRRD-HLQPAITLNPISFPSADLTLKMESARKAWENSQAVPEQGSPG-SGSSAQPVCSVGSSS-VSYSSFS---MPPMPVASVAPSVSMQGSHIPPLYLDGHVFPSQPRLVPP-LTQQPSYQQAT-PQQIPISLHTSLQAQAQLGLRGALPVSQSQEIFSSIPPFRSQVYMHPNLSQASPMVLSGGAALKGPYSAFPGLQPSDLVKSQSGSHYQPINGSTPLVYD----QPTGMSTSQLMDSQLIQVTMPMPGSQLRYGSAQQHLILPQSIQLQQNQNLSVGAPRRMMPPGSQP-VLSGSREVSQMDMKGFQFSDK----PSHSPGIPSGSYRPGSASPSGKASG-APAVASLAGHYTQQVSGPQGSMVMHMRPPSSGPFPTPIQRPIMQVNKPVIIRSPPYPGPNTGPAHTHAHTHNPEGPGKGPEDGLKECVASAAPVKASASRSGAIKPQPLKLEEGKA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*********:.********:*********:*: : :::*:.***********:********:*******.******::*************** ***** .:::* **. * .*********** * *.*. .****.****.**.*.::* *: **** .** *:******** ***.***:..:* *************:********:: .. *:.* : .::.: * .. *.: * :*: *:****** * : *: : : : ..***********. :: * : : : :. :*::.* ** :*.: :* * : * **:*: :*****:***.::**.**:** *.:********************** *:.. :: *:.** :::: .. .* .: :* . . . : :: * *..** .. **.::.* . :: : ..*** **:.:::* ******:****************** ***:**:* ::.*. .: : **:. **. .. .* ::* : ** *.. : : :: . . :.:.. ::: *: **. *: ::**.:*****:*****:* :**: ** *. *..:**** *** *::***********.*****:: :***:**..:*.***:**:: : *...*. * *:.* *.:: **:... :. **. :.* : : . * .* :. : * . * **:*::. **. . * *.:*: . *: .*...* *:* . :* : *. .*:**. . :. .* *. * * : *:***** *:***:***. *.* ::*::********..:.:** : ::....*******..* **.**....*** . *: ::.:*..: :**: *. *****:****************** *** *::.* ****:***:.*:*********..********.**.: *...** ****.**.******:**:**** *:* ** *.*:***:***************** ::***.*** :**. ** .***:*. *.****. :***********.*: ***:**********.******* :.** *****: .*********************.**.*********: **********.** .*.*:****:*** *******:** ::**.**** ***:.*. .***: *.:*:.:**::**** *:***:* ****.** ********* .*.********: ****** **. *** : *::***:*:*. .: .. .. :** :. :. * :* ", "identical_positions": 722, "similar_positions": 388, "identity": "30.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110203-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZRP7-1", "uniprot_id": "QSOX2_HUMAN", "id": "Q6ZRP7-1", "name": "Sulfhydryl oxidase 2", "aln": "MAAAGAAVARSPGIGAGPALRARRSPPPRAARLPRLLVLLAA-AAVGPGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIGYAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTKEFTTGENFKGPDRELRTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVLSLLDNRGSHYVAIVFESNSSYLGREVILDLIPYESIVVTRALDGDKAFLEKLGVSSVPSCYLIYPNGSHGLINVVKPLRAFFSSYLKSLPDVRKK---SLPLPEKPHKEENSEIVVWREFDKSKLYTVDLESGLHYLLRVELAAHKSLAGAELKTLKDFVTVLAKLFPGRPPVKKLLEMLQEWLASLPLDRIPYNAVLDLVNNKMRISGIFLTNHIKWVGCQGSRSELRGYPCSLWKLFHTLTVEASTHPDALVGTGFEDDPQAVLQTMRRYVHTFFGCKECGEHFEEMAKESMDSVKTPDQAILWLWKKHNMVNGRLAGHLSEDPRFPKLQWPTPDLCPACHEEIKGLASWDEGHVLTFLKQHYGRDNLLDTYSADQGDSSEGGTLARGEEEEKRLTPPEVSHGDRDTQSVRPPGALGPRPALPESLHHSLDGKLQSLDGPGAHKEVGGAAPFLGVDFSSLDMSLCVVLYVASSLFLMVMYFFFRVRSRRWKVKHHHPAV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3TMX7-1", "uniprot_id": "QSOX2_MOUSE", "id": "Q3TMX7-1", "name": "Sulfhydryl oxidase 2", "aln": "-MAAARAVARDPGA------YARQPPSLRAARLPRLLFLLAVVAAVGPREGGGARLYREGSDAVWLLDSGSVRSATGNSSAAWLVQFHSSWCGHCIGYAPTWRALAADVRDWAAAIRVAALDCAEEKNQDVCRTYDIHFYPTFRYFKAFTKEFTTGENFKGPDRELRTVRQTMIDFLQNHTEGTWPPACPPLDPIQSSDILSFMDSHSGQYHAIVFESNGSYVGREVILDLIPYENIMVSRALDTDKAFLGTLGITSVPSCYLIYPNGSHGLVNVAKPLRSFFSSHLKSLPDVRKK---SLFLPEKSNKEEKSEVVVWKEFDRAKLYTADLESGLHYLLRVELAAHRSLAGAQLKTFRDFVTVVAKLFPGRPAVKKLLETLQEWLANLPLDKIPYNAILDLVNNKMQISGIFLTSHVKWVGCQGSRLELRGYPCSLWKLFHTLTVQASTHPEALAGTGFEGHPQAVLQAIRRYIRTFFGCKECGEHFEEMAKESMDSVKTPDQAVLWLWRKHNMVNSRLAGHLSEDPKFPKVPWPTPDLCPACHEEIKGLDSWNEGQVLLFLKQHYSRDNLVDAYSVDQGSPGEWEAQGREQEEGKGLNPSGKSWRHHDTGSLRPPHILGPRTDLSKSLHHRLDLRLQSPQGPQALKEAKAVVPFLGVGFSSLDMSLCVVLYVASSLFLMIMYFFFRVRSKRWKVRLYHPAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QJL3-1", "uniprot_id": "F1QJL3_DANRE", "id": "F1QJL3-1", "name": "Sulfhydryl oxidase", "aln": "-MAAAFCLK------------------------------ISIIVGLLFGRAQPARLYTE-EDPVVILSSDSLKQTVLNSSSAWLVQFYSSWCGHCIQYSPTWKALAGDVKDWAQAIRIGVVDCAHEKNFDICKEFGIHFYPTFRYFKAHDTTNDFGKTYQGADRELQTVRQLMVNFIQNHTRQDWPVGCPPLHPARSEDVLSLMGKKTEHYTAVIVEDGNSYIGREVILDLMPYEGLVVKRALSSDQLLMDKLGISSVPSAYLFQPNGTHTVLNVQKKLRFFFSSFLKLLPGVHRKQSTSSLQRPQPGINGQGAQVEWKEFKKSKVYMADLESGLHYLLRVELATHKTLEGEELKTFKDFVTVVAKLFPGHQSVVKLLETLLEWLVSLPLEKIPYDAILDLVNNKMRISGLYLSEQVQWVGCQGSSVALRGYPCSLWTLFHVLTVQAANRPDALANTGFEDDPLAVLQTMRRYIGTFFGCQECGKHFEEMAQESLNQVKTVDEAVLWLWRKHNQVNARLSGSMSEDPMFPKTQWPTPDLCPTCHEEQEGLHVWNEQMVLAFLKQHYSASNISPKYSSSQSEPGP-----PAPDKPKAITKP--NSKIHINQNLKSPEILP-------KHQKRTDSGGEVEKHSGVQIEARPGMTFLGLGFSSVDMSLCVLLYALSCVFLMFMFFFFRFRSKRWKFKNYRPYV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **. .: :: ..: . **** .*.* :*.*.*:: :. ***:******:******** *:***:***.**:*** ***:..:** .*** :*: :.************. . *:.::*.****:**** *::*:****. * .** *.* :..*:**::..: :* *::.*...**:********:***.::*.***. *: :: .**::****.**: ***:* ::** * ** ****.** **.*::* * :. : :. * *:**.::*:* .***************:*::* * :***::*****:******: .* **** * ***..***::***:*:********:***::*:.:::******* *********.***.***:*:.:*:**..****..* ****::***: *****:***:******:**::.*** *:*:****:*** **.**:* :**** *** ********:**** :** *:* ** ******. .*: ** .*.... :: * :. . . : . .::.* * . :: * : . . . *. .***:.***:******:**. *.:***.*:****.**:***.: ::* *", "identical_positions": 341, "similar_positions": 192, "identity": "48.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110204-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A5F8MPH1-1", "uniprot_id": "A0A5F8MPH1_MOUSE", "id": "A0A5F8MPH1-1", "name": "", "aln": "---MAFLWQLPQRLLLLGTTALTVSALGTADLTDLCGQTWQEDALQLRSHSASRKFYFVTPDTDCILWLRAAAPEDRMRFQFRFFLVYSLS-----SAIRITAATQATAAT--------PTTKASSRDPCAPGSYLQFYDGPQEAPRALGPPICGLTIPAPFTSSGPWLGLRLVTRGRQPRVDFLGEVTSFHLGS----CG--TYFRCRNGRCVPRSLLC-DDWNMDNCGDGSDQDSRPPASCGGPSLVPKEMGTLEDN---SSKALTLLVAPGSTAERTPPEGLAPITQEVLEGPWLWWVALASSMLLTCTGLLWCCCCPGWLAWHPGAHRLRLRCCAACNVCHLCPGRVAPGGLWLSWPAFQNQGGHR----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SZI1-1", "uniprot_id": "LRAD2_HUMAN", "id": "Q5SZI1-1", "name": "Low-density lipoprotein receptor class A domain-containing protein 2", "aln": "-MEACCLLQLPQRLLLLGAAALTATALETADLAELCGQTWQGDGLLLRSHAASRRFYFVAPDTDCGLWVQAAAPGDRIRFQFRFFLVYSL--------------TPAPPAL--------NTSSPAPADPCAPGSYLQFYEGPPGAPRPLGSPLCGLNIPVPVASSGPFLGLRLVTRGRQPRVDFVGEVTSFRLGP----CG--AYFRCQNGRCIPSSLVC-DPWGMDNCGDGSDQGSWSPADCRGPSPVPSQTGSTDAH---TSRSLTPSPALGSAGS--------------------LWIAAE---------------------------------------------RSSPAGRDPTRQDAALEGSTE----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5D8-1", "uniprot_id": "A0ACD6B5D8_DANRE", "id": "A0ACD6B5D8-1", "name": "", "aln": "MAAARCIQQLSGWFVLLSLMTRQSHSIETVNVVDFCGQTIQGDGMIVKSHQESRKYYFVSMGTDCHLTMQSATPRDKVQFYFRFFLVYSLLRVSPHSPAPLPESPKGSSASGLTRPDLEPTTEEGPEDPCHAGSYIQFYDGRDRSAPLIGPPLCGKSPPRPVLSTGKFLTLRLVTRGTQPRVDFVGDFTSFRLGFNQSECSGEPYFNCRNGKCIPKSLVCADDKGIDNCGDGSDLIDYPGCNAPQSTPNPPQRHATQPAPMLNVPTLTVSTLKNCATPKAIPDPDSVTDSQSSMSLLALYVVLG--VTAAGVLLCWCCWAPGWFLWRVSVFRFMPCCNSCCASCQFCG-RSCSQNKDHRLAKVTPEGAATPVSSTTTVAV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **. ::**. : :: *.::.::**** * *.: ::** **::***: .*** * :::*:* *:::* ********* . ...* *:. .. *** .***:***:* :. :*.*:** . * *. *:* :* ******* ******:*:.***:** *. .**.*:**:*:* **:* * .:******** . . ... .: * : : : . :** ..: ::. * .. . :*. ", "identical_positions": 100, "similar_positions": 85, "identity": "26.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110208-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9R1S7-1", "uniprot_id": "MRP6_MOUSE", "id": "Q9R1S7-1", "name": "ATP-binding cassette sub-family C member 6", "aln": "MNRGRSMATPGEQCAGLRVWNQTEQEPAAYHLLSLCFVRAASSWVPPMYLWVLGPIYLLYIHRHGRCYLRMSHLFKTKMVLGLALILLYTFNVAVPLWRIHQGVPQAPELLIHPTVWLTTMSFATFLIHMERRKGVRSSGVLFGYWLL---CCILPGINTVQQASAGNFRQEPLHHLATYLCLSLVVAELVLSCLVDQPPFFSEDSQPLNPCPEAEASFPSKAMFWWASGLLWRGYKKLLGPKDLWSLGRENSSEELVSQLEREWRRSCNGLPGH--------KGHSSVGAPETEAFLQPERSQRG--PLLRAIWRVFRSTFLLGTLSLVISDAFRFAVPKLLSLFLEFMGDRNSSAWTGWLLAVLMFAAACLQTLFEQQHMYRAKVLQMRLRTAITGLVYRKVLVLSSGSRKSSAAGDVVNLVSVDIQRLAESIIYLNGLWLLFLWIFVCFVYLWQLLGPSALTAVAVFLSLLPLNFFITKKRGFHQEEQMRQKASRARLTSSMLRTVRTIKSHGWEHAFLERLLHIRGQELSALKTSTLLFSVSLVSFQVSTFLVALVVFAVHTLVAEDNAMDAEKAFVTLTVLSILNKAQAFLPFSVHCIVQARVSFDRLAAFLCLEEVDPNGMIASNSRRSS-KDRISVHNGTFAWSQESPPCLHGINLTVPQGCLLAVVGPVGAGKSSLLSALLGELLKVEGSVSIEGSVAYVPQEAWVQNTSVVENVCFRQELDLPWLQKVLDACALGSDVASFPAGVHTPIGEQGMNLSGGQKQRLSLARAVYKKAAIYLLDDPLAALDAHVSQQVFKQVIGPSGLLQGTTRILVTHTLHVLPQADRILVLANGTIAEMGSYQDLLQRNGALVGLLDGARQPAG-----THDAATSDDLGGFPGGGRPTCRPDRPRPTEAAPVKGRSTSEVQMEASLD-DPEATGLTAEEDSVRYGRVKTTIYLSYLRAVGTPLCTYTLFLFLCQQVASFSQGYWLSLWADDPVVDGRQMHAALRGWVFGLLGCLQAIGLFASMAAVFLGGARASGLLFRSLLWDVARSPIGFFERTPVGNLLNRFSKETDTVDVDIPDKLRSLLTYAFGLLEVGLAVTMATPLAIVAILPLMVLYAGFQSLYVATSCQLRRLESARYSSVCSHMAETFQGSLVVRAFRAQASFTAQHDALMDENQRVSFPKLVADRWLATNLELLGNGLVFVAATCAVLSKAHLSAGLVGFSVSAALQVTQTLQWVVRSWTDLENSMVAVERVQDYARIPKEAPWRLPTCAAQPLWPCGGQIEFRDFGLRHRPELPLAVQGVSLKIHAGEKVGIVGRTGAGKSSLAWGLLRLQEAAEGNIWIDGVPITHVGLHTLRSRITIIPQDPVLFPGSLRMNLDLLQEHTDEGIWAALETVQLKAFVTSLPGQLQYECAGQGDDLSVGQKQLLCLARALLRKTQILILDEATASVDPGTEMQMQAALERWFTQCTVLLIAHRLRSVMDCARVLVMDEGQVAESGSPAQLLAQKGLFYRLAHESGLA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95255-1", "uniprot_id": "MRP6_HUMAN", "id": "O95255-1", "name": "ATP-binding cassette sub-family C member 6", "aln": "------MAAPAEPCAGQGVWNQTEPEPAATSLLSLCFLRTAGVWVPPMYLWVLGPIYLLFIHHHGRGYLRMSPLFKAKMVLGFALIVLCTSSVAVALWKIQQGTPEAPEFLIHPTVWLTTMSFAVFLIHTERKKGVQSSGVLFGYWLL---CFVLPATNAAQQASGAGFQSDPVRHLSTYLCLSLVVAQFVLSCLADQPPFFPEDPQQSNPCPETGAAFPSKATFWWVSGLVWRGYRRPLRPKDLWSLGRENSSEELVSRLEKEWMRNRSAARRHNKAIAFKRKGGSGMKAPETEPFLRQEGSQWR--PLLKAIWQVFHSTFLLGTLSLIISDVFRFTVPKLLSLFLEFIGDPKPPAWKGYLLAVLMFLSACLQTLFEQQNMYRLKVLQMRLRSAITGLVYRKVLALSSGSRKASAVGDVVNLVSVDVQRLTESVLYLNGLWLPLVWIVVCFVYLWQLLGPSALTAIAVFLSLLPLNFFISKKRNHHQEEQMRQKDSRARLTSSILRNSKTIKFHGWEGAFLDRVLGIRGQELGALRTSGLLFSVSLVSFQVSTFLVALVVFAVHTLVAEN-AMNAEKAFVTLTVLNILNKAQAFLPFSIHSLVQARVSFDRLVTFLCLEEVDPGVVDSSSSGSAAGKDCITIHSATFAWSQESPPCLHRINLTVPQGCLLAVVGPVGAGKSSLLSALLGELSKVEGFVSIEGAVAYVPQEAWVQNTSVVENVCFGQELDPPWLERVLEACALQPDVDSFPEGIHTSIGEQGMNLSGGQKQRLSLARAVYRKAAVYLLDDPLAALDAHVGQHVFNQVIGPGGLLQGTTRILVTHALHILPQADWIIVLANGAIAEMGSYQELLQRKGALMCLLDQARQPGDRGEGETEPGTSTKDPRGTSAGRRPELR--RERSIKSVPEKDRTTSEAQTEVPLD-DPDRAGWPAGKDSIQYGRVKATVHLAYLRAVGTPLCLYALFLFLCQQVASFCRGYWLSLWADDPAVGGQQTQAALRGGIFGLLGCLQAIGLFASMAAVLLGGARASRLLFQRLLWDVVRSPISFFERTPIGHLLNRFSKETDTVDVDIPDKLRSLLMYAFGLLEVSLVVAVATPLATVAILPLFLLYAGFQSLYVVSSCQLRRLESASYSSVCSHMAETFQGSTVVRAFRTQAPFVAQNNARVDESQRISFPRLVADRWLAANVELLGNGLVFAAATCAVLSKAHLSAGLVGFSVSAALQVTQTLQWVVRNWTDLENSIVSVERMQDYAWTPKEAPWRLPTCAAQPPWPQGGQIEFRDFGLRYRPELPLAVQGVSFKIHAGEKVGIVGRTGAGKSSLASGLLRLQEAAEGGIWIDGVPIAHVGLHTLRSRISIIPQDPILFPGSLRMNLDLLQEHSDEAIWAALETVQLKALVASLPGQLQYKCADRGEDLSVGQKQLLCLARALLRKTQILILDEATAAVDPGTELQMQAMLGSWFAQCTVLLIAHRLRSVMDCARVLVMDKGQVAESGSPAQLLAQKGLFYRLAQESGLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A140LGU2-1", "uniprot_id": "A0A140LGU2_DANRE", "id": "A0A140LGU2-1", "name": "ABC-type glutathione-S-conjugate transporter", "aln": "------MDTLCSLSGLDPLWDWNVTWYTEHPDLTKCFQHTILVWFPCFYLWICAPFYCLYLKFYYNGRISISSLCCAKMGLALCLASIGFLETVYLLVERSRDIEHLMVFLLSPIIRSLTMILVMLMIHLERLRGFRSSVFLFLFWMLSVVCSLVPLRANIQANIKEGFSADPMRFAAFFTFFSLQLAQLILSCFADQRPDTLKPVYVKNPCPVEDASFLSKLLFWWYGRLVVKGYRSPLKAEDLWSLREEDTSEKIICDLEKEWAKQWAKLQQKKSSLNEAQTLGFKLSSCVKQLFRKLFKEQCTGFVLFRTLAKIFSPYFLTGTLFLVIQDALMFSIPQVLSLLLGYVRDEDAPLWKGYLFAFSLFLLSCLQSLFNHQYMYTCLTVGMRVKTAVMGLVYRKSLVINSAARKTCTVGEIVNLVSADTQKLVDFVMYFNALWLAPIEIALCLFFLWQHLGPSTLAGITTVILIFPLNGFIAKMRSKLQEVQMKHKDERIKLMNEILSGIKILKFYAWEKAFRERVLGYREKELNALKKSQILYSVSIASFNSSTLLIAFAMFGVYVLIDDKHVLDAQKIFVSMALINILKAPLSQLPIAMSTTMQVVVSLKRLGTFLDQDELKLDSVQRVP--YNPNIESVVINNGTFSWSKDSTPCLRRINVKVQRGSLVAVVGHVGSGKSSLLSAMLGEMEKKSGHITITGSVGYVPQQAWIQNATLKDNILFGCEKKDSLYQKVLEACALLPDLEILPARDATEIGEKGLNLSGGQKQRVSLARAVYRNSDIYLLDDPLSAVDAHVGQHIFEKVIGPNGSLKNKTRVLVTHGLSFLPQADLILVMADGEIKEMGSYAELLSRKNAFAELKAFSVSERK------ESATLKGTRKSVSFLSIKDFS--TDLIRGDLGSASIQTMEAISDPKLNQDRDEVGRLTQADKAHTGRVKLEMYVEYFRTIGLAFIIPIIFLYAFQQVASLAYNYWLSLWADDPVINGTQVNTDLKLGVYGALGFAQGIAIFGTTVAISLGGIIASRQLHLDLLNNVLHSPMSFFESTPSGNLLNRFSKEIDAIDCMIPHGLKIMLGYVFKLLEVCIIVLMATPFAGVIILPLTLLYAFIQSFYVATSCQLRRLESVSRSPIYTHFNETVQGASVIRAFGEQPRFILQANCRVDLNQTSYFPRFVASRWLAVNLEFLGNLLVLAAAILSVMGRATLSPGTVGLAVSHSLQVTGILSWIVRSWTDVENNIVSVERVKEYAETAKEAPWTFEDSPLPSDWPRSGSIGFQAYGLQYRKGLDWALKEISLSVNEREKVGIVGRTGAGKSSLALGIFRILEAAKGKIFIDGINIAEIGLHELRSRITIIPQDPVLFSGSLRINLDPFDRYTDEEVWRSLELAHLKTFVSDLPDKLNHECSEGGENLSLGQRQLICLARALLRKTKILVLDEATAAVDLKTDNLIQSTIRTQFEDCTVLTIAHRLNTIMDYTRVIVMDRGNITEIDSPSNLISQHGQFYRMCREAGLV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . .. :*: . : *: ** :: *.* :***: .*:* *::: : . : :* * :** *.:.* : ... * . :. . :*: * : ** :. ::** ** :*.:** .** :*:* * ::* * .* :*::. : : :** :*:::***:.** * : **** *:* ** *** . *: :**: * .:***** .*::**:::. **:** :. : . : : .: * : .* *:::: ::* . ** *** *:*.*.: *::*::***:* :: * ... *.*:*:*. :* :***:**::* ** .: **:::*: ****** *.:.*.:**:.:.*::*****.* *:*.: ::*:*.*** : * :*:.:*** ****:*:.::..: ::*** **:* *. ** **::* .* :* ..:* : :* :.** ** :*:* * :**.**:.* :*:***:.**: **:*:*:.:*.*:.*: :. .::*:* **:::::.**: . : **::: :*. **:.** :** :*:. . : . : : ::..**:**::*.***: **:.* :*.*:**** **:********:***: * .* ::* *:*.****:**:**::: :*: * * . . ::**:**** .*: :* * ***:*:*********:*******::: :*******:*:****.*::*::****.* *:..**:**** * .***** *:*:*:* * ***** :**.*:.*: * : . . .: . . . . * *. : *: * : .* : *. : **** ::: *:*::* .: :**: *****:. .**********.:.* * :: *: ::* ** *.*.:*.: .*: *** ** *. ** :* :**:.*** ** *:******** *::* **. *: :* *.* **** : * :***:* * **** :*** :**:**.:*********. *.: :*: **.**: *:*** *. * * :. :* .* **::**.****.*:*:*** **:.** :*:.:* **.* **::** :**** *.*:**.***:**.:*:***:::** .***** : .. . ** .*.* *: :**::* * *:: :*:.:: ***************** *::*: ***:* *:***: *:.:*** *****:******:**.****:*** ::.::** :* :** .:**::*:.**.:*:::*: *::**:**:**:**********:**:******:** *: :*: : * :**** *****.::** :**:***.*:::* .**::*::*:* ***:.:*:**.", "identical_positions": 625, "similar_positions": 476, "identity": "41.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110208-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1AT66-1", "uniprot_id": "MOT7_MOUSE", "id": "B1AT66-1", "name": "Monocarboxylate transporter 7", "aln": "MRASGQGPQRRRRGWATRDDSAVTFRDPQPRQPAGGARALRGPDPRGPARAHQAGPLLAGARRSQHMVGGAPPRPAETGCSRSRMTQKNSKLCARANVYTQVPDGGWGWAVAVSFFFVEVFTYGIIKSFGVFFNDLMDSFDESNSKISWIISICVFVLTFTAPLSTVLSNRFGHRLVVMAGGLLISLGMITASFSQRVYHMYISIGVISGLGYCFSFLPTVTILSQYFDKRRSVVTAVASTGECFAVFAFAPAITALKEHIGWRYSLLFVGLLQLNIMVCGALLRPIIIQGPGQSPKAVTLEPRR-EVQYMLENEKTRTSIDSIDSGVE-LTTSPKNVPSEAKMEQETRAEQQQTLV-TAPKHSQMKAPLLDFSVLKEKSFICYALFGLFATLGFFAPSLYIIPLGISLGIDPDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRKIYIELICVILLTASLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPMLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMCLAAVCLALVRPCKKGLCQNSHSGENQTDRQRGKALQ---DIPEDFLEMDLGKCEHRAHMKMDPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15403-1", "uniprot_id": "MOT7_HUMAN", "id": "O15403-1", "name": "Monocarboxylate transporter 7", "aln": "------------------------------------------------------------------------------------MTQNKLKLCSKANVYTEVPDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNSRISWIISICVFVLTFSAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPTVTILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGALLRPIFIRGP-ASPKIVIQENRK-EAQYMLENEKTRTSIDSIDSGVE-LTTSPKNVPTHTNLELEPKADMQQVLVKTSPRPSEKKAPLLDFSILKEKSFICYALFGLFATLGFFAPSLYIIPLGISLGIDQDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMSCSIFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKMGLCQHHHSGETKVVSHRGKTLQ---DIPEDFLEMDLAKNEHRVHVQMEPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I3ITI5-1", "uniprot_id": "I3ITI5_DANRE", "id": "I3ITI5-1", "name": "Monocarboxylate transporter 7", "aln": "--------------------------------------------------------------------------------------MSSLKGCMSPNVYSEVPDGGWGWMVAAAFFFVEVFTYGIIKTFGIFLQDLMTEFHETNSRVSWAVSICVFVMAFTAPLSTLLSNRFGHRPVVMVGGFLISLGTITTALTQSIDEMYITMGIVAGLGYCLTFLPTVTILSQYFSKRRSLVTSIASTGECFSMLAFAPAMNALKEQIGWRYCLMVIGVLQASIIVCGALLKPIVIKPKPATQEASTSPLKVLDSKYDAENEFTCTSFDSVDSGVQSISSSQVNLAKEQQKKEEEGESPETPLKQKQEDSSVSRTKLLDFSVLRDASFNCYALFGLFATLGFFAPQIYIIQLSVSRGVSQKSATYMLSAMAVAEIGGRLSMGWVLNRKPIRKIYILLICTVLLCPVLVVFTFVSEFWGLMSCSCLYGFLLGTVASSHIPMLAEDDVIGIQRMSSAVGVYVCIQSFAGLAGPPLGGFLVDQTNNYGSAFYSCAAGMGVGALFLGLVRPAKTGLCFGKRKRKDQQSADRDASSQGSDDSPADFVEMDMETDNSPAKSKPWPV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. * * .***::******** **.:*************:**:*::*** .*.*:**::** :******::*:***:*:******** *** **:*:* * ::::::* : .**:::*:::*****::************.****:**::*******:::*****: ****:*****.*:.:*:** .*:: ****:**.*: : : : : :* *** * **:**:****: :::* *:... : : * . : * . * :: *****:*:: ** ****************.:*** *.:* *:. . *:::**:**:**: **:. *:****:******* ***.:** *..***.:****** ** ::* ::**:..:***:******:**::****.***: ***::*******.*:****:: *. ********* :.*: *.****.* *** :. : : .*. : * * * **:***: . : .: : **", "identical_positions": 280, "similar_positions": 148, "identity": "45.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110208-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPX4-1", "uniprot_id": "P2Y12_RAT", "id": "Q9EPX4-1", "name": "P2Y purinoceptor 12", "aln": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRG--SAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRA-VFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCS-----TSGANKKKGQEGGDPSEETPM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CPV9-1", "uniprot_id": "P2Y12_MOUSE", "id": "Q9CPV9-1", "name": "P2Y purinoceptor 12", "aln": "MDVPGVNTTSANTTFSPGTSTLCVRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGPLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVVIWAFMFLISLPNMILTNRRPKDKDVTKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRG--SAKVPKKKVNVKVFIIIAVFFICFVPFHFARIPYTLSQTRA-VFDCSAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLTSMLRCSN-STSTSGTNKKKGQEGGEPSEETPM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H244-1", "uniprot_id": "P2Y12_HUMAN", "id": "Q9H244-1", "name": "P2Y purinoceptor 12", "aln": "------MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITIDRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRG--VGKVPRKKVNVKVFIIIAVFFICFVPFHFARIPYTLSQTRD-VFDCTAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QLI4-1", "uniprot_id": "A0A8M1QLI4_DANRE", "id": "A0A8M1QLI4-1", "name": "", "aln": "---MEQTTQLSFSNSSVSNSSSCSRDGALKTIVFPVLYSILLILGLSLNALAAWVFLRIPSKSHFIIYLKNIVVADIIMTLTFPFKILSDANVASVGIRIFVCRVSSVLFYLTMYISILFFGLISIDRCRKTMWPFVGTNPKRLLHRKLLSGVIWTSLLALSLPNVILTSR-PNIGERFKCSDLKTELGLRWHEVVNHICQVIFWGNLIIVIICYTLISRELYKSYARTRSPRGTQSKKKHIQVNVFLVLAVFFICFVPFHFARVPYTISQTRALLFSCPQKLFFFKLKESTLWLSSLNSVLDPLIYFFLCKSFRSSLFNVMRLAP---GRCRILRELGTDSAGDQQGNALT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ..:: * ** :. ::**:**::*:: ** *.** :*::* ***:***:*** *::*::* ***********::.: :* :**:*:** **:****** *:***:*** ** ** :.*..** *:** .**: :: :****:***.* *. : *** **:*:** ***:**:******* *::***:**:**::***:**.***. : :*:::::**:::**************:***:**** :*.* : :* :*******:***: ***:**********.** .::: . . :: :.. .: ..: ", "identical_positions": 168, "similar_positions": 99, "identity": "47.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110208-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6GUG4-1", "uniprot_id": "P2Y13_RAT", "id": "Q6GUG4-1", "name": "P2Y purinoceptor 13", "aln": "-----------------MLGTVNTTGMQGFNKSERCPRDTRMTQLLFPVLYTVVFFTGVLLNTLALWVFIHIPSNSTFIIYLKNTLVADLIMTLMLPFKILSDSRLAPWQLRGFVCTFSSVVFYETMYVGIMMLGLIAFDRFLKIVVPFRKTFVKKTAFAKIVSISIWLLMFLISLPNMILN---KEATASTVKKCASLKSPLGLLWHQVVSHTCQFIFWTVFILMLLFYTVIAKKVYDSYRKFKSRDSK-HKRLEAKVFIVMAVFFVCFAPFHFVRVPYTHSQT-TNKTDCRLENQLFLAKESTLFLATTNICMDPLIYIILCKKFTRKVPCMRW-RTKTAASSDEHHSSQTDNITLS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D8I2-1", "uniprot_id": "P2Y13_MOUSE", "id": "Q9D8I2-1", "name": "P2Y purinoceptor 13", "aln": "-----------------MLGTINTTGMQGFNKSERCPRDTRMTQLLFPVLYTVVFLAGILLNTVALWVFVHIPSNSTFIVYLKNTLVADLIMALMLPFKILSDSHLAPWQLRGFVCTLSSVVFYETMYVGIMMLGLIAFDRFLKIIMPFRKTFVKKTAFAKTVSISVWSLMFFISLPNMILN---KEATPSSVKKCASLKSPLGLWWHQVVSHTCQFIFWAVFILMLLFYAVITKKVYNSYRKFRSKDSR-HKRLEVKVFIVMAVFFVCFAPLHFVRIPYTYSQT-TNKTDCRLENQLFIAKEATLFLATTNICMDPLIYIILCKKFTQKVPCVRWGKARTAGSSEDHHSSQTDNITLA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BPV8-1", "uniprot_id": "P2Y13_HUMAN", "id": "Q9BPV8-1", "name": "P2Y purinoceptor 13", "aln": "MTAAIRRQRELSILPKVTLEAMNTTVMQGFNRSERCPRDTRIVQLVFPALYTVVFLTGILLNTLALWVFVHIPSSSTFIIYLKNTLVADLIMTLMLPFKILSDSHLAPWQLRAFVCRFSSVIFYETMYVGIVLLGLIAFDRFLKIIRPLRNIFLKKPVFAKTVSIFIWFFLFFISLPNTILSN--KEATPSSVKKCASLKGPLGLKWHQMVNNICQFIFWTVFILMLVFYVVIAKKVYDSYRKSKSKDRKNNKKLEGKVFVVVAVFFVCFAPFHFARVPYTHSQT-NNKTDCRLQNQLFIAKETTLFLAATNICMDPLIYIFLCKKFTEKLPCMQG--RKTTASSQENHSSQTDNITLG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B745-1", "uniprot_id": "A0ACD6B745_DANRE", "id": "A0ACD6B745-1", "name": "", "aln": "---------------------MN---LSQVNASLKCERDTRVTSILFPCLYAALFLLALVLNSLAAWIFFQIRSSSTFIVYLKNVVVADLLMTLTVPVKALTDAGLGSWHLRAFHCRYSAVLFYTTMYISILLLGFISLDRYLKIVHPFGKCVLQRVRVGRVLCAVTWAVMLSLALPNVILSNRMPQISPGGRLRCTRMKGKMGLLWHEGFNYFCQVVFWGTLALMVVCYTFISRKVFESYRASQSSSDVTSKQTTSKVFVVVGVFFVCFAPFHLARVPYTLSQTRSTSSQCWAQNQLYFAKEITLWISSSNVCLDPLIYVFLCRGFRKKLTATLS-RAPLPHGSLTETSTKIEMPNRGH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :. .* * :* ****:..::** **:.:*: .::**::* *:*.:* *.****:****.:****:*:* :*.* *:*: *..*:**.* * *:*:** ***:.*::**:*::**:***: *: : .::: ..: :. * .:: ::*** **. : :.. :*: :*. :** **: .. **.:** .: **:: *..*::**::*** :* . *: ***:*:.********:*:.*:*** *** ...::* :***::*** **:::::*:*:*****::**: * .*:.. . .* . *:: : . . ", "identical_positions": 130, "similar_positions": 128, "identity": "36.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110208-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AVZ9-1", "uniprot_id": "S43A3_MOUSE", "id": "A2AVZ9-1", "name": "Equilibrative nucleobase transporter 1", "aln": "----------------------------------------------------------MASKGLPLYLATLLTGLLECIGFAGVLFGWTSLLFVFKAENYFSEPCEQDCLLQSNVTGPSDLKAQDEKFSLIFTLASFMNNFMTFPTGYIFDRFKTTVARLI--AIFFYTCATIIIAFTSANTAMLLFLAMPMLAVGGILFLITNLQIGNLFGKHRSTIITLYNGAFDSSSAVFLVIKLLYEQG---ISLRSSFIFMSVCSVWHIARTFLLMPKG--HIPYPLPPNYSYGL-CSRFGASKKENKAAEHETKELRSKECLPPKEENSGPEQQQQQEQQQQQQQQQEQHE---------QHSFRRCALSRRFILHVVWLSIIQLWHYLFIGTLNSLLTKLSGGDKVEVSAYTNAFAITQFFGVLCAPWNGLLMDRLKQKYQKAAKRTGSSSEAVALCSMVPSLALTSLLSLGFALCASIPVMQLQYATFILQVVSRSFLYGCNAAFLTLAFPSEHFGKLFGLVMALSAIVSLLQFPLFKVSPESN-----AVYVSMGLAIFLTLVHPFLVYRECRAEKTKS----SVDA--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LPJ3-1", "uniprot_id": "A0ABK0LPJ3_RAT", "id": "A0ABK0LPJ3-1", "name": "", "aln": "MAQGSRQTDPRHFLLNPETVGTRGLIEVECLPKEISYTPLPVVSEVQDRICGPTSPQTMASQ-LPLYLATFLTGLLECIGFAGVLFGWTSLLFVFKAENYFLKPCEQDCVLGGNTTGLPDLKAQDEKFSLIFTLASFMNNFMTFPTGYIFDRFKTAVARLL--AIFFYTCATLIIAFTSADTAMLLFLAMPMLAVGGILFLITNLQIGNLFGKHRSTIITFYNGAFDSSSAVFLIIKLLYEQG---ISLRHSFIFLSVCSAWHVGRTFLLMPRG--HIPYPLPPNYSYGL-CSRFCTRKEENEAAEHETKELQSRECQSPKEENSGPEQQQQQQQQQQQQQQQQQ-----------QHSFRRCVFSHRFILHVVWLSIIQLWHYLFIGTLNSLLTKLAGEDSVKVSAYTNAFAITQFFGVLCAPWNGLLMDCLKQKYQKEAKRTGLSSEAVALCSMVPSLALTSLLSLGFTLCASIPVIELQYATFILQVVSRSFLYGCNAAFLTLAFPSEHFGKLFGLVMALSAIVSLLQFPLFKVSPESK-----AVYVSMGLAIFLTLVHPFLVYRECRVEKTKP----SVDA--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NBI5-1", "uniprot_id": "S43A3_HUMAN", "id": "Q8NBI5-1", "name": "Equilibrative nucleobase transporter 1", "aln": "----------------------------------------------------------MAGQGLPLHVATLLTGLLECLGFAGVLFGWPSLVFVFKNEDYFKDLCGPDAGPIGNATGQADCKAQDERFSLIFTLGSFMNNFMTFPTGYIFDRFKTTVARLI--AIFFYTTATLIIAFTSAGSAVLLFLAMPMLTIGGILFLITNLQIGNLFGQHRSTIITLYNGAFDSSSAVFLIIKLLYEKG---ISLRASFIFISVCSTWHVARTFLLMPRG--HIPYPLPPNYSYGL-CPGNGTTKEEKETAEHENRELQSKEFLSAKEETPGAGQKQELR------------------------SFWSYAFSRRFAWHLVWLSVIQLWHYLFIGTLNSLLTNMAGGDMARVSTYTNAFAFTQ-FGVLCAPWNGLLMDRLKQKYQKEARKTGSSTLAVALCSTVPSLALTSLLCLGFALCASVPILPLQYLTFILQVISRSFLYGSNAAFLTLAFPSEHFGKLFGLVMALSAVVSLLQFPIFTLIKGSLQNDPFYVNVMFMLAILLTFFHPFLVYRECRTWKESP----SAIA--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F4C3-1", "uniprot_id": "E7F4C3_DANRE", "id": "E7F4C3-1", "name": "", "aln": "-----------------------------------------------------MMAYKGSSGKVVRYKLTLATGLLECLCFAGVVFGWASLVFVLKTDGYFGDLCSNATDAGGEFS--SDCGLQDEHFSLVFTVASFMNNFLTLPNGFLYDHFGTMATRLL--AIFLYTTGTLIVAFSNKALSVLLFPALSFIAVGGILFLMTNMQVGNLFGSHRSTIITVYNGAFDSSSVIFLIIKVLYEKG---VSLRSSFLFLSACNLIHLIRTLFLMPKS--HIPYPIPQDYQYGISCAKSNSYNVEEYEAKREASSDRSRRAEEELLETDSIKLTDNPEKD----------------------SFRSCVLSWFFLWHLVWLSVMQLRHYFFIGTLNPMLNRLANQNPVTVSEYTNAFAFTQFCGVLCAPWNGLLMDRHKRK----PLDPDVSEREADLRSSILSLLLTSLQCFLFSICASIPFLPLQYLTFILQVLNRSFLYGGNAAFISIAFPARHFGKLYGLVMSLSAVVSLLQYPCFALNKALG-GDPLYVNILLTILTLLAFIHPVYVFLHCRELAKHRENSRTLEASIQETSMY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04991-1", "uniprot_id": "FMP42_YEAST", "id": "Q04991-1", "name": "Protein FMP42", "aln": "-----------------------------------------------------------MTSTRTLRYAQVACACIWCLFSAGIIFGFAALKPILISEGVYHELCDPKDGDR------LLCTAQDLKLNFIFALSATVTNIMALPVGKILDMYGPRVCGIIGSCLLFLASGNFISAKHLVSLWDPYLVGYTLLAVAGPFVFISCFQLANSFPQRSGTVLALLTGSFDSSSALFLLYRLLYQNWFPTLNVSRFFTLYLIVPVFILACQLTIMPHSSYKTVNHIAKIAVEGLDENGRLIEGDTGSGIIPDEQERQSLIAIEREEDSIPSRPQRRKSVLETYVEDKLQKKSGGIFGVLHGKSAYEQIKSPWFYLMLLFALVAMLRINYFIATVRTQEEYLLNDPDLALKLNSIFDMLLPLGGAVSIPFIGLLLD------------------HTDTLSTLTILFTTSTAIGVFGLIPNS--FTWNLIGIVLLVVYRPFYYTVVSDYSSKVFGFDTFGTVYGLLSCICGIFNMSQNLLDKWTHTTFNMN--PFPINLTLVILTVVFSLTLTFYIRSQILPKPVNERGLSSNYQTI---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : *: **::**:.:* :: :. : . * ** ::.::*::.: :.*::::* * : * : . . :: .::: : ..:* * : . .::::.* :.::: :*:.* * .: .*:::. .*:*****.:**: ::**:: :.: * : : : :**:. : :. *: : . :* :. . * * * ::: : * **.*:.. : . :. : : *.:. *: ***:* . * : * ** * : .. : : ::* *: *.* * : : : .* **.::**: .:..:..: * . : : : : ... .: : ", "identical_positions": 65, "similar_positions": 152, "identity": "10.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110208-9", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZVG2-1", "uniprot_id": "A0A8I5ZVG2_RAT", "id": "A0A8I5ZVG2-1", "name": "", "aln": "MDDSEVESTASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANSLMANGTLTRRHQNGRFVGDADLERQKFSDLKLNGPQDHNHLLYSTIPRMQEPGQIVETYTEE-DPEGAMSVVSVETSDDGTTRRTETTVKKVVKTMTTRTVQPVPMGPDGLPVDASAVSN-NYIQTLGRDFRKNGNGGPGPYVGQAGTATLPRNFHY-PPDGYGRHYEDGYPGGSDNYGSLSRVTRIEERYRPS------MEGYRAPSRQ--DVYGPQPQVRVGGSSVDL---HRFHPEPYGLEDDQRSMGYDDLDYGM--MSDYGTARRTGTP--SDPRRRLRSYEDMIGEEVP--PDQYYW---APLAQHERGSLASLDSLRKGMPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPILVGLLDHPKKEVHLGACGALKNISFGRDQD-NKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPN---EDCKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIP---QAERYQEALPSVANSTGPHAASCFGA-KKGKDEWFSRGKKPTEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTSEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGG-QQNSSWNFSEDTVVSILNTINEVIAENLEAAKKLRETQGIEKLVLINK-SGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDDSTLPLIDRNQKSDKKPDREEIPMSNMGSNTKSLDNNYSTLNERGDHNRTLDRSGDLGDMEPLKG------------------------------APLMQKI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30999-1", "uniprot_id": "CTND1_MOUSE", "id": "P30999-1", "name": "Catenin delta-1", "aln": "MDDSEVESTASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANSLMANGTLTRRHQNGRFVGDADLERQKFSDLKLNGPQDHNHLLYSTIPRMQEPGQIVETYTEE-DPEGAMSVVSVETTDDGTTRRTETTVKKVVKTMTTRTVQPVPMGPDGLPVDASAVSN-NYIQTLGRDFRKNGNGGPGPYVGQAGTATLPRNFHY-PPDGYGRHYEDGYPGGSDNYGSLSRVTRIEERYRPS------MEGYRAPSRQ--DVYGPQPQVRVGGSSVDL---HRFHPEPYGLEDDQRSMGYDDLDYGM--MSDYGTARRTGTP--SDPRRRLRSYEDMIGEEVP--PDQYYW---APLAQHERGSLASLDSLRKGMPPPSNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPILVGLLDHPKKEVHLGACGALKNISFGRDQD-NKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPN---EDCKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIP---QAERYQEALPTVANSTGPHAASCFGA-KKGKDEWFSRGKKPTEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIAELLTSEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGG-QQNSSWNFSEDTVVSILNTINEVIAENLEAAKKLRETQGIEKLVLINK-SGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDDSTLPLIDRNQKSDKKPDREEIPMSNMGSNTKSLDNNYSTLNERGDHNRTLDRSGDLGDMEPLKG------------------------------APLMQKI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60716-1", "uniprot_id": "CTND1_HUMAN", "id": "O60716-1", "name": "Catenin delta-1", "aln": "MDDSEVESTASILASVKEQEAQFEKLTRALEEERRHVSAQLERVRVSPQDANPLMANGTLTRRHQNGRFVGDADLERQKFSDLKLNGPQDHSHLLYSTIPRMQEPGQIVETYTEE-DPEGAMSVVSVETSDDGTTRRTETTVKKVVKTVTTRTVQPVAMGPDGLPVDASSVSN-NYIQTLGRDFRKNGNGGPGPYVGQAGTATLPRNFHY-PPDGYSRHYEDGYPGGSDNYGSLSRVTRIEERYRPS------MEGYRAPSRQ--DVYGPQPQVRVGGSSVDL---HRFHPEPYGLEDDQRSMGYDDLDYGM--MSDYGTARRTGTP--SDPRRRLRSYEDMIGEEVP--SDQYYW---APLAQHERGSLASLDSLRKGGPPPPNWRQPELPEVIAMLGFRLDAVKSNAAAYLQHLCYRNDKVKTDVRKLKGIPVLVGLLDHPKKEVHLGACGALKNISFGRDQD-NKIAIKNCDGVPALVRLLRKARDMDLTEVITGTLWNLSSHDSIKMEIVDHALHALTDEVIIPHSGWEREPN---EDCKPRHIEWESVLTNTAGCLRNVSSERSEARRKLRECDGLVDALIFIVQAEIGQKDSDSKLVENCVCLLRNLSYQVHREIP---QAERYQEAAPNVANNTGPHAASCFGA-KKGKDEWFSRGKKPIEDPANDTVDFPKRTSPARGYELLFQPEVVRIYISLLKESKTPAILEASAGAIQNLCAGRWTYGRYIRSALRQEKALSAIADLLTNEHERVVKAASGALRNLAVDARNKELIGKHAIPNLVKNLPGG-QQNSSWNFSEDTVISILNTINEVIAENLEAAKKLRETQGIEKLVLINK-SGNRSEKEVRAAALVLQTIWGYKELRKPLEKEGWKKSDFQVNLNNASRSQSSHSYDDSTLPLIDRNQKSDKKPDREEIQMSNMGSNTKSLDNNYSTPNERGDHNRTLDRSGDLGDMEPLKGTTPLMQDEGQESLEEELDVLVLDDEGGQVSYPSMQKI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q686-1", "uniprot_id": "A0A8M9Q686_DANRE", "id": "A0A8M9Q686-1", "name": "", "aln": "--MEQCENAASLLASVREQEMQFERLTRALEEERRSVGPSGTLPRPLP--------------TLQNGRITGDAELERLKLSEGYING----------TQYRMLDPGHIVESVTVESDPHEALPIISVETGDDGTTRRTETTVKKVTKTTTTRTVIPSVSDTLSLDGTGSVTGMPSYNSPMDRVYRPPP--GPMDYP----TSTVPRNYHYGPPAGYD-DYRSVPP--SEAYTSLSRGTRMDDRYRPVDGYRTLDSAYRTHSRPQLDPYSAQPQVGRMGSAVEISALQRFVPEPYGLEDDQRSLGYDEPDYGMGPAMHYSTMPRLAHPHHAPPPRRTGSYEGTLDGDMSGAGDMFYWGGGAPLAQGERGSMASLDSTLRKGPAPTAWRQPELPEVIAMLNYRLDPVKSNAAAYLQHLTFKNDKVKSEVRRLKGIPALVSMLDNPKKEVHYAACGALKNISYGRDPD-NKIAIKNCDGIPALVRLLRKTRDQDLTDTITGTLWNLSSHDSVKMEIVDHALHALSDEVMVPHSGWERGNEGGEESCKPRHLEWETALTNTTGCLRNVSSERSEARRKLRECSGLVDSLMYIVQSQINCKDVDNKLIENSVCLLRNLSYQVHREIP---GCERYLESIPVNQGPLPSQKGGCFSS-RKGKDEWFSKGKR-EDDGTSDTIDIPKRTTPAKGYELLFQPEVVRVYTSLLKESKNPSVLEAAAGAVQNLCAGRWTYGRYIRATMRQEHGLPMMTELLSHGNDRVVRAMSGALRNLAIDARNRELLGKHAVPNLVANLPGGGQSQPARALSEETVVSVLSTMAEVVGSSVDAAKTLRSAQGIERLVLINK-DSNRSDREVRGAGLVLQIVWGFKELRRTLEKDGWKKTDFMVNLNPPNNTRSNGGYEESTLPLIDRGGKQDR--EKDMIPLNDIGP------DAYSTIDQRGRRN-TLDDTLDRSDRDAPQGGMYGERRGSLPLLDSYDENLIVCITRREFPPPAYCPC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7PLI0-1", "uniprot_id": "Q7PLI0_DROME", "id": "Q7PLI0-1", "name": "", "aln": "------MEARSLKHSLIGLNMNSTHINMDLSLTHEPANMQSQFG------------------SFQN---------------------------------YDQFSAAGYSSTPLYITKPTGVGAITKVAPHCSQNKIETNSTDNSIPDIENHPLATTVRYVQAGQYEDTSEYGVAGLTCGIDSEY---TAEAVVPYCYTS----------------------------DANYTGIQNTTSSIKPFSGR----------------------------------------PFNDNINGAEAVADSQCRTFKSSAEFKLPQFAMSSINTVP------QRLEEKDDYIEGSEN------------------------------DICSTMRWRDPNLSEVISFLSNPSSAIKANAAAYLQHLCYMDDPNKQRTRSLGGIPPLVRLLSYDSPEIHKNACGALRNLSYGRQNDENKRGIKNAGGIAALVHLLCRSQETEVKELVTGVLWNMSSCEDLKRSIIDEALVAVVCSVIKPHSGWDAVCCG--------ETCFSTVFRNASGVLRNVSSAGEHARGCLRNCEHLVECLLYVVRTSIEKNNIGNKTVENCVCILRNLSYRCQEVDDPNYDKHPFITPERVIPSSSKGENLGCFGTNKKKKEANNSDALNEYNISADYSKSSVTYNKLNKGYEQLWQPEVVQYYLSLLQSCSNPETLEAAAGAIQNLSACYWQPSIDIRATVRKEKGLPILVELLRMEVDRVVCAVATALRNLAIDQRNKELIGKYAMRDLVQKLPSG-NVQHDQNTSDDTITAVLATINEVIKKNPEFSRSLLDSGGIDRLMNITKRKEKYTSCVLKFASQVLYTMWQHNELRDVYKKNGWKEQDFVSKHFTAHNTPPSSPNNVNNTLNRPMASQGRTRYEDRTIQRG--------TSTLYSANDSSGAVMSNESAMLSEMVRKQL---------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: *: *: : : ::. *. :. .. . ** ... .: .* . .: .* . . .. .*::* :.: . . . . . * . . :. : . * . * .:.. * . : * : * * * . . .:. * :* . :. : . .. **:*:*.***::*. ..:*:********* : :* * .* * *** ** :*. . *:* *****:*:*:**: * ** .***..*:.***:** :::: ::.: :**.***:** :.:* .*:*.** *: .*: *****: . :.:.: *::* ****** ..** **:*. **:.*:::*::.* :: ..* :**.**:******: :. . : . . . .**.: :* *: * . . : :. : . . .. :*** *:*****: * ***:....* ***:***:***.* * . **:::*:*:.*. :.:** :*** * : ******:* **:**:**:*: :** :**.* : : *::*: ::* *: **: .. : ::.* .: **::*: *.* . : :. :: *. ** :* .:*** :*:***: ** : . .: .. : .. : : * . **: :. * . . . . ", "identical_positions": 207, "similar_positions": 250, "identity": "20.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110209-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0CD95-1", "uniprot_id": "CQ067_RAT", "id": "P0CD95-1", "name": "Uncharacterized protein C17orf67 homolog", "aln": "MEKLFVLVFALTLLAFSSEASPILTEKQAKQLLRSRRQDRPSKPGFPDEPMREYMHHLLALEHRAEEQFLEHWLNPHCKPHCDRNIVQPV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3V3I5-1", "uniprot_id": "CQ067_MOUSE", "id": "Q3V3I5-1", "name": "Uncharacterized protein C17orf67 homolog", "aln": "MEKLFVLVFALALLAFSSDASPILTEKQAKQLLRSRRQDRPNKPGFPDEPMREYMHHLLALEHRAEEQFLEHWLNPHCKPHCDRNIVHPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q0P5P2-1", "uniprot_id": "CQ067_HUMAN", "id": "Q0P5P2-1", "name": "Uncharacterized protein C17orf67", "aln": "MKTLPVLVLSLTLLTVFSETSPILTEKQAKQLLRSRRQDRPSKPGFPDEPMREYMHHLLALEHRAEEQFLEHWLNPHCKPHCDRNRIHPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FGZ8-1", "uniprot_id": "E7FGZ8_DANRE", "id": "E7FGZ8-1", "name": "", "aln": "MKPLACLFF-VALLTFFTEANPIIQESFAKQLLRTKRQ----KPGHPDEPMNEHLLHMQRLEQKARETNMEHWLNPHCFPRCDRNYGYPV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * *.: ::**:. :::.**: *. ******::** ***.*****.*:: *: **::*.* :******** *:**** **", "identical_positions": 45, "similar_positions": 25, "identity": "50.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110214-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q499U1-1", "uniprot_id": "S2538_RAT", "id": "Q499U1-1", "name": "Mitochondrial glycine transporter", "aln": "MGVSAEPRSLSVARAGLASPVIEKARSALLPSQDVEDTVETLMLHPVIKAFLCGSISGTCSTLLFQPLDLLKTRLQTLQP-SDVGPRRVGMLSVFLKVVRTESLLGLWKGMSPSIVRCVPGVGIYFGTLYSSKQYFLRGH---------------------PPTALESVILGMGSRSVAGVCMSPITVVKTRYESGAYSYESVYAALRSIYCSEGSRGLFRGLTATLLRDAPFSGLYLMFYSQTRATVLHGADELDAALMP----------LVNFSCGVFAGILASLVTQPADVIKTHMQLSTVKCQCIGQVATLILKTHGLRGFFHGSVPRALRRTLMAAMAWTVYEEMMAKMGLKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91XD8-1", "uniprot_id": "S2538_MOUSE", "id": "Q91XD8-1", "name": "Mitochondrial glycine transporter", "aln": "MGVSAEPRSLSVAGAGLASPVIEKARSALLQSQDVEDTVETLMLHPVIKAFLCGSISGTCSTLLFQPLDLLKTRLQALQP-SDLGPRRVGMLAVFLKVVRTESLLGLWKGMSPSIVRCVPGVGIYFGTLYSSKQYFLRGH---------------------PPTALESVILGMGSRSVAGVCMSPITVIKTRYESGTYSYESIYAALRSIYCSEGHRGLFRGLTATLLRDAPFSGLYLMFYSQTRTAVLHGTAQLDAALIP----------LINFSCGIFAGVLASLVTQPADVIKTHMQLSPVKFQWIGQAATLIFKNHGLRGFFHGSVPRALRRTLMAAMAWTVYEEMMARMGLKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96DW6-1", "uniprot_id": "S2538_HUMAN", "id": "Q96DW6-1", "name": "Mitochondrial glycine transporter", "aln": "--------------------MIQNSRPSLLQPQDVGDTVETLMLHPVIKAFLCGSISGTCSTLLFQPLDLLKTRLQTLQP-SDHGSRRVGMLAVLLKVVRTESLLGLWKGMSPSIVRCVPGVGIYFGTLYSLKQYFLRGH---------------------PPTALESVMLGVGSRSVAGVCMSPITVIKTRYESGKYGYESIYAALRSIYHSEGHRGLFSGLTATLLRDAPFSGIYLMFYNQTKNIVPH--DQVDATLIP----------ITNFSCGIFAGILASLVTQPADVIKTHMQLYPLKFQWIGQAVTLIFKDYGLRGFFQGGIPRALRRTLMAAMAWTVYEEMMAKMGLKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CAT2-1", "uniprot_id": "S238B_DANRE", "id": "P0CAT2-1", "name": "Mitochondrial glycine transporter B", "aln": "--------------------------------------MEVALAHPALKAFMCGSLSGTCSTLLFQPLDLVKTRLQTLQNNMHPGAPKVGMITVLFNVIRTEKLLGLWKGVSPSFMRCIPGVGIYFSTFYSLKQHYFQEG---------------------SPSAGEAVLLGAGARCVAGVAMLPFTVIKTRFESGRYNYISVAGALKSVCQNEGPKALYSGLTATLLRDAPFSGIYVMFYSQAKKALPQ--EISSSSIAP----------LVNFGCGVVAGILASLATQPADVIKTHMQVSPALYPKTSDAMRHVYVKHGLSGFFRGAVPRSLRRTLMAAMAWTVYEQLMARMGLKS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q07534-1", "uniprot_id": "S2538_YEAST", "id": "Q07534-1", "name": "Mitochondrial glycine transporter", "aln": "-------------------------------------MTEQATKPRNSSHLIGGFFGGLTSAVALQPLDLLKTRIQQDKK-----------ATLWKNLKEIDSPLQLWRGTLPSALRTSIGSALYLSCLNLMRSSLAKRRNAVPSLTNDSNIVYNKSSSLPRLTMYENLLTGAFARGLVGYITMPITVIKVRYESTLYNYSSLKEAITHIYTKEGLFGFFRGFGATCLRDAPYAGLYVLLYEKSKQLLPMVLPSRFIHYNPEGGFTTYTSTTVNTTSAVLSASLATTVTAPFDTIKTRMQLEPSKFTNSFNTFTSIVKNENVLKLFSGLSMRLARKAFSAGIAWGIYEELVKRFM---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . :: * :.* *:: :*****:***:* : :: :: . :. * **:* ** :* * .:*:. : :. : : * :: * :* :.* *:**:*.*:** *.* *: *: : .** .:: *: ** *****::*:*:::*.::: : * * ..:.:. **: .* * *.***:**: . :. : .: :* * * *::: *.:** :**::: :: ", "identical_positions": 71, "similar_positions": 87, "identity": "19.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110214-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GET5-1", "uniprot_id": "A0A8I6GET5_RAT", "id": "A0A8I6GET5-1", "name": "", "aln": "MKKSSDTAGSGAPNSDSQLPEKFHRTHSARAAKIKARKDN-REISAAKIQKAWFIYVDKTLFKLLKHTVCAAEYCVAHELLKKVSPVEAALLKDPSMKCKVRFR-------LTGETFPPCIVFKIFFKGDTHSYKYFSGKNLLKPSSKAVADAYKIMGERKFYQQIMQDEYFFQKFKIADRMDIVTVQDYMQYCSLIDETPASSGGKNNHWRRLNLRSIPKTMMMYDIVDYAESGVISDRLQKEMKYLLQKPQTEEMRQHQLDIVSKVRYPSIATVRPFYQPWEQQKKMKHLGRRSKQAQKKVEKMKKAYMETKEKLASSQEPLASTSQIKKKVIFYTPSFEILKVDELIDSDLESEEKELFAWYQDLYVKHSSLF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96LI9-1", "uniprot_id": "CX058_HUMAN", "id": "Q96LI9-1", "name": "Uncharacterized protein CXorf58", "aln": "MNRSSNVPRKGILKSGTRSLQKVRRVHFANARNARSLLSMLKDISAQIIQRAWLSHTNKMIFRLLKHAICAAEFYVTHEILKKVAPLEAKLIKDPTMQCKIRFR-------FRGETFPPFIVFKIFLHTDGHGYKYFSGKNVLMPSSKAVDDACKLMGERKFHRIIMEDERIFPKSKVTDIMDVVTMQDYVQYRSFFDEAPAFSGGRNNSWRKLNLENIPRTMLMYDIVHYSESGVISNRLRNEMKFLLQRPVTQEIHKHQLRIVSEIRGP-YLTVQPLYRPYKQQNQVKFLGRRSKQAQMKVEKMRKVYLAKEKNTSEVTEPKTGPSGTK-----------------------------------DNYHLHS-IF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JNC1-1", "uniprot_id": "A0AC58JNC1_DANRE", "id": "A0AC58JNC1-1", "name": "", "aln": "--------------------------------------MQSYEDCARKIQACWRSFRDRRLFRLLMNTVRSAEQCLASAVLRQLSPKEADLLKDPSLKCKLRFRWMFFTQQFAGPRFPPSLVFKIFHTGGGR-RQYLSGEKLLASSG--------------------------------------------QYNSHLDELPACVGGRENGWRFLSLKVLSRDVALKKRLKPGIRAFSAGGLNAITSHFAGQQLSHRSSQTSSRCSRRAKNT-ADRKRRLYGLKETRRGSDDEQGMKEKGLEKWDIIVLPSVETEDNDDSSSQSEWEDEAEKLCIWS------------------------------EQLNIDAI--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* ** .* . :: :*:** ::: :** :: :*::::* ** *:***:::**:*** : * *** :***** . : :*:**:::* .*. ** * :** ** **::* ** *.*. :.: : : . :. . .. :. *. ..: : :.. : . . : . : :* : :. . .::. * : : : .:.: . :. . * : .: ", "identical_positions": 54, "similar_positions": 90, "identity": "14.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110216-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6NKL6-1", "uniprot_id": "T200C_HUMAN", "id": "A6NKL6-1", "name": "Transmembrane protein 200C", "aln": "MIATGGLLRISARKQDPLRPPSQIP-KRKRKAKKRRKNDVVVVKGKLKLCSISGLIALCGILVLLVGIAMAVVGYWPKATGTNREGGKQLPPAGSSHRVPTTANSSSSGSKNRSRSHPRAPGGVNSSSAGAPRSTPPARAASPSSSS---------TSVGFFFRIFSGYLHSDKLKVFGPLIMGIGIFLFICANAVLHENRDKKTKIINLRDLYSTVIDVHSLRAKDLAAAAAAAAAAAASSSSSAPAAAPPGAIPLNGFLSYVQSRGLELKPGGCGGSGDAFGAAAMLAKGSWPPHPAAPSGG--RPRGAASPPDLASSPRCPREPPSLAEAVYSVYRERSGVAGSRR-------AAAATAAAAASSCSSPAPCSPPESWGRQSTASSFVDSSLSAFALLPLQGGRDRGGDAEGASCSWQRPPGERGSQEIPRGELDLSMTNLRGAEGSMRGARREPEEPEGAVAARAARGQGGRLPRTGRYAALRRRSTSGLPDYRAPPSPEPPPSPGSADPDSSPLAKAASPSPPLRLE-GSPPTRRDSGSSQSDDPSSSNKGYTPLR-EAGTSTESVLDAVAGQTRDSAVAAPVLGAEQSSPEGASQEPPTAEQPQPVQRQFTNKEKLIMISRSHAIGVEE-ELESTGI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "J3QK46-1", "uniprot_id": "J3QK46_MOUSE", "id": "J3QK46-1", "name": "", "aln": "MIATGGLLRISARKQDPLRPPSQVP-KRKRKAKKRRKNDVVVVKGKLKLCSISGLIALCGILVLLVGIAMAVVGYWPKANAANRGGSKQLLPVGSSHRIGAISNSSN-GNKNPAKSHSGTPGGANSSSVGGPWSPPPARSAATSSSSSSSSSSSSSTSVGFFFRIFSGYLHSDKLKVFGPLIMGIGIFLFICANAVLHENRDKKTKIINLRDLYSTVIDVHSLRAKDLAAAAAAAAAAAASSSAAAPGSASHGAAPLNGFLSYVQSRGLELKPGSCAGSADAFGAAAMLARGSWP-HPTGLDGGSGETQEAGSPPDLASSPRCPREPPSLTEAVYSIYRERSSRAGHRRTTVAAVAAATATVTAAASGGSSPAPCSPTGSWGRQSTTSSLVGSSLSAFALLPLQGDRDRDGDSEGASCSWHRPPGERGSRDLPRGELDLSLTDLRGAEGGARWASCEPGEPEGAKTARTARGQGGRLPRTRRYAAWRRRSTSGLPDYRAPPSPEPPPSSSAENLDSGPSATAATPSLPLRPEEDSPRVRRDSHSSQSDDQSSSNKGYTPLR-EADTSVESVVDVVAKKRLDCEDVTDPS-TEHSSPEGPSPGP-TRAEPLSVQRQFTNKEKLFLISRSHTPGVEDPELKKSSN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FAA8-1", "uniprot_id": "E7FAA8_DANRE", "id": "E7FAA8-1", "name": "", "aln": "MIATGGLLRISARRQDSLRAKNRAENKRKRKAKKKRKNEVVVVKGKLKLCSVSGLVAAVGILVLLVGIAMAVLGYWPKES--------PLYPG----LINTVSSPRTYGTTERELVNVSIRWDLLDKDFNGSNGTAEVDSP----------------KLGAFAAFINRYLYSDKLKVFGPLIMGIGIFLFICANAVLHENRDKKTKIINLRDIYSTVIDIHSLRTKEP--------------------------APLNGFVNYCQSK-------------DTKSYISPHKSGSWP-----SPGSGRLDTSSMIPSRRPSTNQSSLDKQSLTDTVYSIYRDQK---------------------------------PELKQWESRTIVSTSVNAFTLPMMRLNNRGTSERRGSDKTGEAKREFLDAEAICRRLEDLVASRSMTKAK-----VESAQTHPEPPQDSLEVYRSSGSLQGAPRVSLQGSQVKLLTQCSPSHRATGS--HLSLSALSDYSRSIDEDICSPIPAERQQ---VRSRRLSCPRLEG---LSCGGYTKLEGLGGESFESTDNATFSRESSVEVLEKDQ--ELQTECG-------------AVRQYSKKQKLLMVSQSDTT-LEDVEMDSMEI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************:**.**. .: ********:***:************:***:* *************:***** . * * : : :.. . *..: : . ... ... ... . :. .:* * ::. **:*****************************************:******:****:*: *****:.* **: *: . : **** *. : *. .*: :.. : **:::***:**::. . .* :: .*: *.: .: * :* :* *. : .... . .* .: : . *:*. : . * .* *:.: . : *. **. .: : *. *.:**. * . .. : . . .:* . * : ** * . .. * *** *. .. * **. :.. : . * .: * . **:::*:**:::*:*.: :*: *:.. ", "identical_positions": 189, "similar_positions": 149, "identity": "29.39%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110216-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7Z7J7-1", "uniprot_id": "LHPL4_HUMAN", "id": "Q7Z7J7-1", "name": "LHFPL tetraspan subfamily member 4 protein", "aln": "---MLPSQEASKLYHEHYMRNSRAIGVLWAIFTICFAIINVVVFIQPYWVG-------DSVSTPKPGYFGLFHYCVGSGLAGRELTCRGSFTDFSTIPSSAFKAAAFFVLLSMVLILGCITCFSLFFFCNTATVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRDMCGAKTGKYSLGDCSVRWAYILAIIGILNALILSFLAFVLGNRQTDLLQEELKPE-------NKDFVGSTVSSVLRPGGDVSGWGVLPCPVAHSQGP------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5U4E0-1", "uniprot_id": "LHPL4_MOUSE", "id": "Q5U4E0-1", "name": "LHFPL tetraspan subfamily member 4 protein", "aln": "---MLPSQEASKLYHEHYMRNSRAIGVLWAIFTICFAIINVVVFIQPYWVG-------DSVSTPKPGYFGLFHYCVGSGLAGRELTCRGSFTDFSTIPSSAFKAAAFFVLLSMVLILGCITCFALFFFCNTATVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRDMCGAKTGKYSLGDCSVRWAYILAIIGILNALILSFLAFVLGNRQTDLLQEELKQE-------NKDFVGTTVSSVLRPGGDVSGWGVLPCPVAHTQGP------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3AUX7-1", "uniprot_id": "A0A8M3AUX7_DANRE", "id": "A0A8M3AUX7-1", "name": "", "aln": "--MQHQSPEVARLYQTEFIRSARAIGVMWAVCTLCFAVIEVVILIQPSWVGTRELHYRGGGPAPPTGTLGLFEVCLETDWP--VPECRGSLRTLTPLP--AFQSPAVLVCMSLTMVWASVGCLCLFRFCNAATVYKICAWLQLTAGFCLALACVLFPDSWSCAEMRALCGERVSSFSPGNCSVHWAFILAILGVLDAGILATLAFVLGNRQDALLPDNAKD------------------------GDVT--GLLLAA-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W068-1", "uniprot_id": "Q9W068_DROME", "id": "Q9W068-1", "name": "", "aln": "MGTKIEYVDTTHLYASKYIRNSKAIGVLWAIFTICYAIIGIVAFVTPEWIG--------DPDNDGAGRLGLWQQCQRDEIFD---NCRRRWESIFEVPTFSFQLATFFMLGAIALALLTIFFLVCLLFMKSTRVFHLCGWMQIISAICMIVACAAFPFGWNSDDFRKICGPEANRFELGLCGIRWAYPLAIIGCIDGVVLATLAFILATRHVRLQPDPIYQNSLYKGEINNAYLTDAISLAGSRKSNPRITGLNLQPILLVAPPNEDSISQFSRYH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.::** .::*.::****:**: *:*:*:* :* :: * *:* . .* :**:. * ** : :* :*: .:.:: ::.: : : : * ::: *:::*.*:*: :.:*: :.* ** .*.. :* :** ... :. * *.::**: ***:* ::. :*: ***:*..*: * : .: *: . ", "identical_positions": 54, "similar_positions": 84, "identity": "19.57%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110218-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97366-1", "uniprot_id": "EVI5_MOUSE", "id": "P97366-1", "name": "Ecotropic viral integration site 5 protein", "aln": "MVTTKMTAAFRNPNRRQVATDKVAEKLSSTLSWVKNTVSHTVSQMASQVASPSASLHTTSSSTTLSTPTQSPSSPSKLSPDDLELLAKLEEQNRLIETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHLEEDSWILWGRIVNEWDDVRKKKEKQVKELVRKGIPHHFRAIVWQLLCNAQSMTIKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDRELVTVRAVLSSLDCCCMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEYLPELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQMNQAELMQLDMEGMLQHFQKVIPHQFDGGPEKLIQSAYQVKYNSKKMKKLEKEYTTIKTKEMEEQGEIKRLRTENRLLKQRIETLEKHKCSSTYNEDFVLQLEKELVQARLSEAESQCALKEMQDKVLDIEKKNNSFPDENNIARLQEELIAVKLREAEAIMGLKELRQQVRTLEEHWQRHLARTSGRWKDPPKKNAVNELQDELMSIRLREAETQAEIREMKQRMMEMETQNQINSNQLRRAEQEVNSLQEKVCSLSVKNKGLLAQLSEAKRRQAEIECKNKEEVMAVRLREADSIAAVAELQQHIAELEIQKEEGKLQGQLNRSDSNQYIRELKDQIAELTHELRCLKGQRDFSSRPPFDGIHIVSHLIGDDELFHSSDEDFIDSSLQESAIGFPLHRKSGPMSLNPALADGSESEAEDGMLGPQESDPEAPQKQPPQR-ESYSTTV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60447-1", "uniprot_id": "EVI5_HUMAN", "id": "O60447-1", "name": "Ecotropic viral integration site 5 protein homolog", "aln": "MVTNKMTAAFRNPSGKQVATDKVAEKLSSTLSWVKNTVSHTVSQMASQVASPSTSLHTTSSSTTLSTPALSPSSPSQLSPDDLELLAKLEEQNRLLETDSKSLRSVNGSRRNSGSSLVSSSSASSNLSHLEEDSWILWGRIVNEWEDVRKKKEKQVKELVHKGIPHHFRAIVWQLLCSAQSMPIKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDREVGYCQGSAFIVGLLLMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQEHLPELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALLQMNQAELMQLDMEGMLQHFQKVIPHQFDGVPDKLIQAAYQVKYNSKKMKKLEKEYTTIKTKEMEEQVEIKRLRTENRLLKQRIETLEKHKCSSNYNEDFVLQLEKELVQARLSEAESQCALKEMQDKVLDIEKRNNSLPDENNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQRHLARTTGRWKDPPKKNAMNELQDELMTIRLREAETQAEIREIKQRMMEMETQNQINSNHLRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNKEEVMAVRLREADSIAAVAELRQHIAELEIQKEEGKLQGQLNKSDSNQYIGELKDQIAELNHELRCLKGQRGFSGQPPFDGIHIVNHLIGDDESFHSSDEDFIDNSLQETGVGFPLHGKSGSMSLDPAVADGSESETEDSVLETRESNQVVQKERPPRRRESYSTTV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RA30-1", "uniprot_id": "F1RA30_DANRE", "id": "F1RA30-1", "name": "", "aln": "-------------------------------------------------------------MDSLTVSSLSSTPGSELSTDEMKLLAKLEEQNRLLETDSKSLYSVNGVLRNPTSPKTFS---------LEEN---IWENVINEWEDWSKRKVGQIKVLTRRGVPAHLRAMVWQLLCDSGNVSVRPQYSDLLKSSSPSETLIHRDLTRTFPHHQLFHNHQSISKETLFNVLKAYSVLDQEIGYCKGSVFIVGLLLTQMAEEEAFCVFVRLMKDFRMRELYKSSRDELGCCIYQFDSMIKEQLPELHSHFQTQGFQTSVFSSSWFYSIFLSSLPISAAMRIFDIFMCEGLEIVFRVGLAVLDMKQTELIKLDNEGMMKCLQNLESWESN--PDLMIEAAYQIKYNGSQMKQFRKDYEAIKAKELEEQEELKGLCSENKHLKHRLAILER-RCS----EKLVSQLRKELEKTQLNIASSQNALKEMQANTSQLEEIS-AAPDEHSVLYLRTELISCRLREAEALTELKQLKNHIKDMDEKLQQVLCGGQQRVS-----STQNDLQVELLSTRLKETLTQAILKESRHALMQLQTQNEIHRNQLKRTEAHVSSQRDHLQELTSHNKDLHSQLQQIRCHFLAVQNKWK-----------------------------GNEDG---------DAGNLIERLQKQITELQIQIQTFS--------------------------------------------------KCAPSSCQPSTSASLEHKDT-----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:..: *.:. *:**.*:::***********:******* **** **. *. . * ***: :* .::***:* *:* *:* *.::*:* *:**:******.: .:.:: ***:*** :**.*.**:**::**:*.*::*::::*:.:*.****:****::*:*: :. :. **.*********:**:*:*:***:*.* *** *:***:.**:* ****. ***:*.*:**:::**** :***:::*:. * *******.************:*:*:*:**::** ***:: :*:: . : : *: :*::***:***..:**::.*:* :**:**:*** *:* * :**: **:*: **: :** *.:* **.*** :::*. *.** ****** :. ::*: . : ***:.: *: ***: :******: **:*::::: ::*: *: *. * . .: *:** **:: **:*: *** ::* :: :*:::***:*: *:*:*:* .* * :::: *: :**.* :**.: : : :: * * :*:* *:.: * .*:.**:** ::: :. *... * :*: : . * : ", "identical_positions": 279, "similar_positions": 218, "identity": "34.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110221-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2Y9-1", "uniprot_id": "KLOT_RAT", "id": "Q9Z2Y9-1", "name": "Klotho", "aln": "MPAR------APPRRLPRLLLLRLLSLHLLLLTLR-------------------------ARCLSAEPGQGAQTWARFARPPVPEASGLLHDTFPDGFLWAVGSAAYQTEGGWRQHGKGASIWDTFTHHPRAIPEDSPIVMAPSGAPLPPLPSTGDVASDSYNNVYRDTEGLRELGVTHYRFSISWARVLPNGTAGTPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDTYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGVRGSSRLGYLVAHNLLLAHAKVWRLYNTSFRPTQGGRVSIALGSHWITPRR-MTDYHIRECQKSLDFVLGWFAKPIFIDG-DYPKSMKNNLSSLLPDFTESEKRFIRGTADFFALSFGPTLSFQLLDPSMKFRQLESPSLRQLLSWIDLEYNHPQIFIVENGWFVSGTTRRDDAKYMYYLKKFIMESLKAIRLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKELLPKSSALFYQKLIENNGFPPLPENQPLEGTFPCDFAWGVVDNYIQVDPTLSQFTDPNVYLWDVHHSKRLIKVDGVVAK--KRKPYCVDFSAIRPQITLLREMRVTHFRFSLDWALILPLGNQTQVNRTVLHFYRCMVSELVHANITPVVALWQPATPHQGLPHALAKHGAWENPHTALAFADYANLCFEELGHWVKFWITINEPNSRNMTYRAGHHLLKAHALAWHLYDDKFRAAQKGKISIALQVDWIEPACPFSQKDKEVAERVLEFDVGWLAEPIFGSGDYPHVMREWLNQKN-----NFLLPYFTEDEKKLIRGSFDFLALSHYTTILVDWEKED-------PIKYNDYLEVQEMTDITWLNSPNQ-VAVVPWGLRKALNWLRFKYGDLPMFVTANGIDDDPHAEQDSLRMYYIKNYVNEALKAYVLDGINLCGYFAYSLSDRSVPKSGFYRYAANQFEPKPSIKHYRKIIDNNGFLGSGTLGRFCPEEYTVCTGCGFFQTRKSLLAFISFLVFAFVTSLALIYYYSKKGRRRYK---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35082-1", "uniprot_id": "KLOT_MOUSE", "id": "O35082-1", "name": "Klotho", "aln": "MLAR------APPRRPPRLVLLRLLLLHLLLLALR-------------------------ARCLSAEPGQGAQTWARFARAPAPEAAGLLHDTFPDGFLWAVGSAAYQTEGGWRQHGKGASIWDTFTHHSGAAPSDSPIVVAPSGAPSPPLSSTGDVASDSYNNVYRDTEGLRELGVTHYRFSISWARVLPNGTAGTPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDTYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGVRGSSRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGRVSIALSSHWINPRR-MTDYNIRECQKSLDFVLGWFAKPIFIDG-DYPESMKNNLSSLLPDFTESEKRLIRGTADFFALSFGPTLSFQLLDPNMKFRQLESPNLRQLLSWIDLEYNHPPIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIRLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKELLPKSSALFYQKLIEDNGFPPLPENQPLEGTFPCDFAWGVVDNYVQVDTTLSQFTDPNVYLWDVHHSKRLIKVDGVVAK--KRKPYCVDFSAIRPQITLLREMRVTHFRFSLDWALILPLGNQTQVNHTVLHFYRCMISELVHANITPVVALWQPAAPHQGLPHALAKHGAWENPHTALAFADYANLCFKELGHWVNLWITMNEPNTRNMTYRAGHHLLRAHALAWHLYDDKFRAAQKGKISIALQADWIEPACPFSQNDKEVAERVLEFDIGWLAEPIFGSGDYPRVMRDWLNQKN-----NFLLPYFTEDEKKLVRGSFDFLAVSHYTTILVDWEKED-------PMKYNDYLEVQEMTDITWLNSPSQ-VAVVPWGLRKVLNWLRFKYGDLPMYVTANGIDDDPHAEQDSLRIYYIKNYVNEALKAYVLDDINLCGYFAYSLSDRSAPKSGFYRYAANQFEPKPSMKHYRKIIDSNGFLGSGTLGRFCPEEYTVCTECGFFQTRKSLLVFISFLVFTFIISLALIFHYSKKGQRSYK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UEF7-1", "uniprot_id": "KLOT_HUMAN", "id": "Q9UEF7-1", "name": "Klotho", "aln": "MPAS------APPRR-PRPPPP-SLSLLLVLLGLG-------------------------GRRLRAEPGDGAQTWARFSRPPAPEAAGLFQGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIALSSHWINPRR-MTDHSIKECQKSLDFVLGWFAKPVFIDG-DYPESMKNNLSSILPDFTESEKKFIKGTADFFALCFGPTLSFQLLDPHMKFRQLESPNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIEKNGFPPLPENQPLEGTFPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWDVHHSKRLIKVDGVVTK--KRKSYCVDFAAIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPYTRNMTYSAGHNLLKAHALAWHVYNEKFRHAQNGKISIALQADWIEPACPFSQKDKEVAERVLEFDIGWLAEPIFGSGDYPWVMRDWLNQRN-----NFLLPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKED-------PIKYNDYLEVQEMTDITWLNSPSQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGIDDGLHAEDDQLRVYYMQNYINEALKAHILDGINLCGYFAYSFNDRTAPRFGLYRYAADQFEPKASMKHYRKIIDSNGFPGPETLERFCPEEFTVCTECSFFHTRKSLLAFIAFLFFASIISLSLIFYYSKKGRRSYK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GMY9-1", "uniprot_id": "A0AC58GMY9_DANRE", "id": "A0AC58GMY9-1", "name": "", "aln": "MAGGNRGTWGKPSRRKSVILWRPELRSAWIPIYPSSAWVIIDRFPERTTTKKTGPDGLHHSEGTASDPGAGQHTWDTFSKLPYPDDKAFLYDTFPDKFMWAVGTAAYSVEGAWEKDGKGKSIWDTFTRG-------------------GTRVSRGDVGSDSYHNIPGDLRALQQLGVSHYRFSLSWPRIFSNGTKESYNDKGVEYYKNLIRGLKDIKVQPVVTLYHWDLPDSLQTLFGGWSNSVMVELFRDYADFCFKTFGSDVKFWITIDNPFVVAWHGYGTGVVAPGIKNDSDLPFRVGHNLLKAHAAAWHLYDERYRAAQGGRVSMALGSHWIKPSR-TRQESRKACQRSLNFVLGWFARPLFVDG-DYPPCMKDNLTHRLPSFTEAESAYVNGTADFFALSHGPALSFQLINDSLRFGQTEDLGLRMLLYWVRAEYNNPPIFVVESGWYGSGNTKTKDAKHMYYLKRFIMETLKAIHVDRVNVIGYTAWSLLDGYEWYREYAIRRGLFYVDFNTPDLKREPKASATFYSKLIEKNGFPQLPENRPAHGAFPCDFAWGVAANSIQVDTTPTQFTDTNVYIWNISGNGELKKLPGLQAPHLRRTPHCADYGSIRQQVSDLLRMQVSHFHFSLNWSSIVPTGHVSDANETLLRYYYCFVSELQKVNITPVVTLWHHTGKLSSLPAPMEASDGWQSEKTVQAFVDYARLCFHRLGAHVKLWITLNEPNDEDLEYTVGHQLLRAHALAWHVYDREFRKAQGGKASLVLHMDWVEPAFSFNREDVAPADRVLDFRVGWFAEPIFGKGDYPAVMRSWLQQRNTIDLFNYHLPTFSEEDRLLVKGTYDFFAISHFTTSMVYDGVED-------KYTFKDKLQVQLISDVTWIMSPRRNSPVVPWGLRKALNWVNSRYKGVPIYVMANGVQEDTARFKDSLRSYYLYNYVNEALKAYMLDAVNLKGYFAYAFSDQRDPGFGMYGHVQEEVISKSSLGHYKNIIRHNGFPAPGTSQHQCPHAPAQGSGR-YVLTKKPVVGFLSLVSSCMLITMCLVIYYAFKRHKLTTKK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VV98-1", "uniprot_id": "Q9VV98_DROME", "id": "Q9VV98-1", "name": "Cytosolic beta-glucosidase", "aln": "-------------------MMQIILPLFVLT--------------------------------------------ASCLGSPVSQTR-----RFPNDFLWGVGSSSYQIEGGWNADDKGESIWDFLTHTHP---------------EKIVDRSNGDVSADSYHQWKRDVQMVKELHVGTYRFSLSWPRIMPGGYMNHVSTAGIKYYSNLIDELLRYNITPMVTIYHWELPQKLQELGG-WTNPEIIPLFKDYARLVLEMYGDRVKIWTTVNEPWHVCEHGYGVDYMAPSYNYPGIPAYLCGHNLLKAHAEVVHMYRELFQPRQGGRMGITLDTSWPEPRDPNSAEDREASERAMQFYVGWFGHPIFSKHGNYPKVMIERIR--------------------------------------------------------------------------------------------------------------------------------------------------------NLSKEQGFGARSR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPEFTTEEIHRIRGTSDFFGINSYTSNLVTSNGHNNTGKFPVPSFNHDMGVVESQEGVDWPGSGSVWLKVYPKGMYNLLMWIHREYNAPEIIVTENGVSD-RGGLEDYARVDYYNLYLSAVLDA-MEDGANISGYIAWSLMDSYEWKAGFSEKFGLYHVDFNSPQRTRTPKIS-----ARVFAQLCKTNTIDWSYRPKLDEEQQLVAMAQLPAEARTSGASGAVSWSLMGILLLALLR", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : * .: **: *:*.**:::*. **.*. ..** **** :*: : ***.:***:: * . :::* * ****:**.*::..* . *:.** .*: * : *:**:***:**: ** * *:* : *:*** : :. :*. ** * *:::*: *. ***... :**. . : .**** *** . ::* ::. ***::.::*.: * * . .:::::* :***.:*:* . :** * :.: :* :.:** .. ** *: :: ::*: **:.:. :*: :* .: :* *: .: * * * * *: : * *:. .* : : **:.: .* * * *:. .*.* : * *: **:*::: * *: * : :. . . : * : . .: :: : : . :: ", "identical_positions": 131, "similar_positions": 155, "identity": "12.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110222-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O15444-1", "uniprot_id": "CCL25_HUMAN", "id": "O15444-1", "name": "C-C motif chemokine 25", "aln": "MNLWLLACLVAGFLGAWAPAVHTQGVFEDCCLAYHYPIGWAVLRRAWTYRIQEVSGSCNLPAAIFYLPKRHRKVCGNPKSREVQRAMKLLDARN-KVFAKLHHNTQTFQAGP-HAVKKLSSGNSKLSSSKFSNPISSSKRNVSLLISANSGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35903-1", "uniprot_id": "CCL25_MOUSE", "id": "O35903-1", "name": "C-C motif chemokine 25", "aln": "MKLWLFACLVACFVGAWMPVVHAQGAFEDCCLGYQHRIKWNVLRHARNYHQQEVSGSCNLRAVRFYF--RQKVVCGNPEDMNVKRAMRILTARKRLVHWKSASDSQTERKKSNHMKSKVENPNS---TSVRSATLGHP-RMVMMPRKTNN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B7Z9-1", "uniprot_id": "A0ACD6B7Z9_DANRE", "id": "A0ACD6B7Z9-1", "name": "", "aln": "---MRFSIFVFIFLLGFIYLTTAQGSYEDCCLKYVRKINHSMKNRVIRYRKQEVDGGCNIPAIVFTLK-QGRMFCTDPREKWVHELMQRVDRLKARPYLKRKTSRG----------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :* *: .: . :** :***** * * : .:. *: ***.*.**: * * : : : .* :*.. *:. *: : : . * . ", "identical_positions": 25, "similar_positions": 31, "identity": "16.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110222-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O15444-1", "uniprot_id": "CCL25_HUMAN", "id": "O15444-1", "name": "C-C motif chemokine 25", "aln": "----MNLWLLACLVAGFLGAWAPAVHTQGVFEDCCLAYHYP-IGWAVLRRAWTYRIQEVSGSCNLPAAIFYLPK----RHRKVCGNPKSREVQRAMKLLDARN-KVFAKLHHNTQTFQAGP-HAVKKLSSGNSKLSSSKFSNPISSSKRNVSLLISANSGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35903-1", "uniprot_id": "CCL25_MOUSE", "id": "O35903-1", "name": "C-C motif chemokine 25", "aln": "----MKLWLFACLVACFVGAWMPVVHAQGAFEDCCLGYQHR-IKWNVLRHARNYHQQEVSGSCNLRAVRFYF------RQKVVCGNPEDMNVKRAMRILTARKRLVHWKSASDSQTERKKSNHMKSKVENPNS---TSVRSATLGHP-RMVMMPRKTNN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QBE9-1", "uniprot_id": "F1QBE9_DANRE", "id": "F1QBE9-1", "name": "C-C motif chemokine 25", "aln": "METQSSTMKFQILALLLLLACMYPSIAQGYYENCCLKYVTG-IKKNMRRNIMSYRVQLTDGGCNIPAVVFKMRLKKQLKPKSVCADPRSDWVQAIIKELDEKNKRAM------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P86792-1", "uniprot_id": "CC21B_MOUSE", "id": "P86792-1", "name": "C-C motif chemokine 21b", "aln": "---MAQMMTLSLLSLVLALCIPWTQGSDGGGQDCCLKYSQKKIPYSIVR---GYRKQEPSLGCPIPAILFLPRK---HSKPELCANPEEGWVQNLMRRLDQPP--APGKQSPGCRKNRGTSKSGKKGKGSKGCKRTEQTQPSRG-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P84444-1", "uniprot_id": "CC21A_MOUSE", "id": "P84444-1", "name": "C-C motif chemokine 21a", "aln": "---MAQMMTLSLLSLVLALCIPWTQGSDGGGQDCCLKYSQKKIPYSIVR---GYRKQEPSLGCPIPAILFSPRK---HSKPELCANPEEGWVQNLMRRLDQPP--APGKQSPGCRKNRGTSKSGKKGKGSKGCKRTEQTQPSRG-----------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * : . ::* ::*** * * : * *: * . .* : * * :*.:*.. *: :: * . ", "identical_positions": 17, "similar_positions": 22, "identity": "10.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110222-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LM30-1", "uniprot_id": "A0ABK0LM30_RAT", "id": "A0ABK0LM30-1", "name": "Laminin subunit gamma-2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSKVETDLGALELFGGLNTCAT--VCDCNGKSRQCVFDQELHRQTGNGFRCLNCNDNTAGVHCERCREGFYRQRDRDRCLPCNCHSKGSLGAGCDNSGQCRCKPGVVGQRCDRCQPGFHMLTDAGCTRDQRQLDSKCDCDPAGISGPCDSGRCVCKPAVTGERCDRCRAGYYHLDRANPEGCTQCFCYGHSDSCHTSADFSVHKITSTFNQDEDGWKAVQRNWA---PAKLHWSPRHQDVFSSARRSDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAYDVILEGAGLQIRAPLMPPGKTLPCGITKTYTFRLNEHPSSHWSPQLSYFEYRRLLRNLTALLIRATYGEYSTGYIDNVTLISARP-VSGAPAPWVERCVCPAGYKGQFCQECASGYKRDSARLGPFGTCVPCNCQGGG-ACDPDTGDCYSGDENPDIECADCPIGFYNDPHD--PRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGFFGDPFGERGPVRPCQRCQCNNNVDPSASGNCDQLTGRCLKCIYNTAGIYCDQCKAGYFGDPLAP-----------------------------------------------------------------------------------------------------NPADKCRACNCNPVGSEPGECRSDGSCVCKPGFGGLNCAHA--------AALTSCPACYNQVKTQMDQFAQQLQNLEALVSKAQGGNG-AVPSEELEGRMQQAEQALRDILREAQISEG------AMRALSLQLAKARSQENNYKNRLDDLKMTVERIRALGSQYQNRVQDTSRLISQMRLSLAES-EASLQNTNIHSSEHYVGPNGFKSLAQEAARLADSHVESANTMKQLTRETEDYSKQALSLARKALSG--GGGSGVLDSSVVQGLMGKLEKTKSLTQQLSREGTQADIEADRSYQHSLRLLDSAS-QLQGIRDSSFQA-EAKRIRQKADSLSNLVTKQMDAFTSVRNNLGNWEKETRQLLQTGKDRRQTSDQLLSRANLAKSRAQEALSMGNATFYEVENILKNLREFDLQVEDRKAEAEEAMKRLSYISQKVADASDKTQQAETALGSATADTQRAKNAATEALEITSEIEQEIGSLN-LEANVTADGALAMEKGLATLKSEMREVEGELARKELEFHTDKDSLQLVITEAQQADARAKSTGVTIQDTLNTLEGILRLIDQPDAVDEEGLMLLEQELFQAKTQIN-SRLRPLMSELEDRARRQSNHLHLLETSIDGILADVKNLENIRDNLPPGCYNTQALEQQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61092-1", "uniprot_id": "LAMC2_MOUSE", "id": "Q61092-1", "name": "Laminin subunit gamma-2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPALWLSCCLGVALLLPAAQATSRREVCDCNGKSRQCVFDQELHRQTGSGFRCLNCNDNTAGVHCERCREGFYRHRDRDRCLPCNCHSKGSLSAGCDNSGQCRCKPGVTGQRCDRCQPGFHMLTDAGCTRDQGQLDSKCDCDPAGISGPCDSGRCVCKPAVTGERCDRCRPGYYHLDRANPEGCTQCFCYGHSASCHASADFSVHKITSTFSQDVDGWKAVQRNGA---PAKLHWSQRHRDVFSSARRSDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRQPSAYDVILEGAGLQIRAPLMAPGKTLPCGITKTYTFRLNEHPSSHWSPQLSYFEYRRLLRNLTALLIRATYGEYSTGYIDNVTLVSARP-VSGAPAPWVERCVCPAGYKGQFCQECASGYKRDSARLGPFGACVPCNCQGGG-ACDPDTGDCYSGDENPDIECADCPIGFYNDPHD--PRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGFFGDPFGERGPVRPCQRCQCNNNVDPNASGNCDQLTGRCLKCIYNTAGVYCDQCKAGYFGDPLAP-----------------------------------------------------------------------------------------------------NPADKCRACNCSPMGSEPGECRGDGSCVCKPGFGGLNCDH---------AALTSCPACYNQVKIQMDQFTQQLQSLEALVSKAQGGGGGGTVPVQLEGRIEQAEQALQDILGEAQISEG------AMRAVAVRLAKARSQENDYKTRLDDLKMTAERIRALGSQHQNRVQDTSRLISQMRLSLAGS-EALLENTNIHSSEHYVGPNDFKSLAQEATRKADSHAESANAMKQLARETEDYSKQALSLARKLLSG--GGGSGSWDSSVVQGLMGKLEKTKSLSQQLSLEGTQADIEADRSYQHSLRLLDSAS-QLQGVSDLSFQV-EAKRIRQKADSLSNLVTRQTDAFTRVRNNLGNWEKETRQLLQTGKDRRQTSDQLLSRANLAKNRAQEALSMGNATFYEVENILKNLREFDLQVEDRKAEAEEAMKRLSSISQKVADASDKTQQAETALGSATADTQRAKNAAREALEISSEIELEIGSLN-LEANVTADGALAMEKGTATLKSEMREMI-ELARKELEFDTDKDTVQLVITEAQQADARATSAGVTIQDTLNTLDGILHLIDQPGSVDEEGMMLLEQGLFQAKTQIN-SRLRPLMSDLEERVRRQRNHLHLLETSIDGILADVKNLENIRDNLPPGCYNTQALEQQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13753-1", "uniprot_id": "LAMC2_HUMAN", "id": "Q13753-1", "name": "Laminin subunit gamma-2", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPALWLGCCLCFSLLLPAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGSLSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCDAGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASCRSSAEYSVHKITSTFHQDVDGWKAVQRNGS---PAKLQWSQRHQDVFSSAQRLDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRHPSAHDVILEGAGLRITAPLMPLGKTLPCGLTKTYTFRLNEHPSNNWSPQLSYFEYRRLLRNLTALRIRATYGEYSTGYIDNVTLISARP-VSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGG-ACDPDTGDCYSGDENPDIECADCPIGFYNDPHD--PRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAP-----------------------------------------------------------------------------------------------------NPADKCRACNCNPMGSEPVGCRSDGTCVCKPGFGGPNCEH----------GAFSCPACYNQVKIQMDQFMQQLQRMEALISKAQGGDG-VVPDTELEGRMQQAEQALQDILRDAQISEG------ASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQNRVRDTHRLITQMQLSLAES-EASLGNTNIPASDHYVGPNGFKSLAQEATRLAESHVESASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRLLDSVS-RLQGVSDQSFQVEEAKRIKQKADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQEALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAERALGSAAADAQRAKNGAGEALEISSEIEQEIGSLN-LEANVTADGALAMEKGLASLKSEMREVEGELERKELEFDTNMDAVQMVITEAQKVDTRAKNAGVTIQDTLNTLDGLLHLMDQPLSVDEEGLVLLEQKLSRAKTQIN-SQLRPMMSELEERARQQRGHLHLLETSIDGILADVKNLENIRDNLPPGCYNTQALEQQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RET4-1", "uniprot_id": "A0A8M1RET4_DANRE", "id": "A0A8M1RET4-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWKMKSSWIILCAFCIWTPVHGTVRSSSACSCHGKAR-------FCRADQLGLYCLNCQGNTQGRHCESCKEGYYHQRAGDNCVPCNCNPAGSQGPVCSSNGQCTCKQGIHGDKCDRCHDGSPVTANG--------------CEPLRLR---------------------CWSRNNGRLTYNTEECLPCFCNGHSNVCSSAEGYSVYNITSPFENGPEGWRAATAQGVNPSQVQFRWSPTHKDLEVISKEILPVYLFAPATYLGNRALSYGQTLTFSLRLDRGVRRPSTSDVVLEGAGLKVSASLGDLRTVVPCGKKITYTFRLDEQPGSKWKPQLSSAEFQTLLSNLTAIKIRGTFGENGRGYLDDVSLVSAKL-GPGTPALWVEKCRCPAEYDGHFCEHCATGFRRLIPGQGPRSPCVPCSCQGG--ACDPETGGCYSADEIP--NLQMCPRGYYVNRQL--SNSCQKCPCREGDSCYVIGGTQEVTCTRCPRGTTGSRCEICDDGFYGDPLGEYGPRKQCQPCQCYGHVDQNAVGNCDRRTGQCRKCLNHSTGPNCEYCEAGYHHN---------------------------------------------------------------------------------------------------------YPTEPCQACNCNRQGSVSNSCSDKGQCECKEGYDGLRCEE------------STCPSCFNPVKSKIEVYARQLQEMEDLF-KGFGGNEAPVSDAQMDQAVRAAEVMVRNLESRANELTN------TEKQLQDKLASISRSQLREDRNMEALLTSVNGIRNNDQQYRTEVSEIRKLISDVRSKLQQA-KRDMQEIEIPSGDAVPGSGTLSDLVQRAADLAEQHQGEALTVEGIADNSLAQSEKALDLIRGIINR------ENKVKDEIRDLKREYEADVNKVLDMDRKANQLTDAAGKESGEAQNALQQLS-DLEKKLPKPLTK-EIAGVVSMFDNLKGLVEGNLSQYSDLQQYMLNEQKETGDLLIKAKNFQQIQDELLARANAAEAVKNQSLEIFANNKDSLEKTLETLKGFDDQIGVKKDLADAAISKLPAVNATIQKAIADNMQTQDILDAMADPFRDAQETIDTLTSNVYKLEGMTSSLP-SSS-DILEAASKLKEDVDGLKTEASATRDRLNEEKSKAKAQINEAKNAVVESNGVLENAKKARNAVNDTLQDIADIMSSLGTPGTIDDKRVADLENAITKSRRRVE-DELRPKLRELEAKDAQQRATITGMINDIDTILADIANLEEIHKNIPEGCFNIPPIERP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P15215-1", "uniprot_id": "LAMC1_DROME", "id": "P15215-1", "name": "Laminin subunit gamma-1", "aln": "MKRSRWSHSGSSTARLLLIGVLFASCSTAILGAQRPPINSAGGHELRGTTFMPALECYDPYGRPQKCLPEFINAAYQLQIESTNTCGEQNDNHFCIQTMNQNHKNCEFCKYNDHNPSFLTDLHDPQSPTWWQSETMFEGIQHPNYVNLTLHLGKSYDITYVRILFRSPRPESFTIYKRTSESGPWIPYQFYSATCRDTYSLPDSRAIRKGEGEAHALCTSEYSDISPLRDGEIAFSTLEGRPSGINFERSGELQEWVTATDIRITLDRLNTFGDELFGDSQVLKSYFYAISDIAVGARCKCNGHASKCVPSTGMHGERTLVCECRHNTDGPDCDRCLPLYNDLKWKRSTSTEVNECKACNCNGLADKCFFDANLFNRTGHGGHCLDCRENRDGPNCERCKENFYMRDDG-YCVNCACDPVGSRSLQCNSHGKCQCKPGVTGDKCDRCDNNYYQFGPHGCQQCGCDSGGSHQNTPACDT---ETGICFCKENVEGRRCNECKPGFFNLDKNNRFGCTPCFCYGHTSECMTAPGYSIVSVTSNFNKFKERWTAADLNQR---EVDIKYNQYSRSIGTTAQGNEHVYFQAPDRFLGDQRASYNRDLKFKLQLVGQVANTGVSDVILEGAGSRISLPIFAQGNGIPDQGVKEYTFRLHEHHDYQWQPSQSARGFLSILSNLTAIKIRATYSVQGEAILDDVELQTAHRGAAGHPATWIEQCTCPEGYLGQFCESCAPGYRHSPARGGPFMPCIPCDCHGHADICDSETGRCICQHNTHGDNCDQCAKGFYGNALGGTPNDCKRCPCPNDGACLQIN-EDTVICTECPKGYFGSRCEQCSDGFFGDPTGLLGEVQTCKSCDCNGNVDPNAVGNCNRTTGECLKCIHNTAGEHCDQCLSGHFGDPLALPHGRCDRCSCYEAGTEQDEQSITRCDQVTGQCQCKPNVIGRDCGECQPGYFNIRSGNGCENCLCDPVGSYNSTCDRYSGQCHCRPGVMGQRCDQCENYFYGFSSEGCKPCECDESGSKGFQCDQNGQCPCNDNVEGRRCDRCKENKYDRHRGCIDCPDCYNLVQDAADLHRAKLFNLSQTLDEIARTPVTNDDEFEAKLKAVQEKVAVLAQDARDNSGDGGQTYAEVIDDLHKHLDSVREHLVSADKFQADANGEIDRARQNYTILDQITENAKKELQQALDLLNDEGAQALARAKEKSVEFGQQSEQISDISREARALADKLESEAQFDLKNAKDAKDAVEKAHQLAKSAIDLQ-----LKIGTELRSEVGLELSHVKQSLGTVVQTSKEALRKANEVYDTALTLLNDVNRQTQPEIDISQLKKDAVAANERADELLKQITELSNSNGELFADFETEQELTEALLKRAEQQQLEDIELLERAKAAHDKATKAVEQGDNTLKEANNTYEKLAGFQSDVQRSSESAEKALQTVPNIEKEIQNAESLISQAEEALDGANKNANEAKKNAQEAQLKYAEQASKDAELIRRKANETKVAARNLREEADQLNHRVKLTEMDIFKLEESSTKDDNLVDDAKRKVGQAKADTQEAQKQIEKANADLTAIKDELENLKDINTGDLDRLENRLATVEGEINRVNLTGRIEKYREQRTIQKNLIDKYDAELRELKDEVQNIGLISKALPDSCFSRNRLEP-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*.*:* : : . * **:*. * * :** *::.:* : *: * *.. ** . *.. *:* ** *: * :**** . * * . * * *** **: * :: :*: .:** * : : * *. : ..:::. :.: :: **: ** :**:: **.: *.*. :: .... **:***** :: .: . :* *****.*: . :*.*. * : :* ****: **.*:. . . :*:* * :*: .* ** *:*:* ** * *:**: **.*::: . ** .*:**.*:* **.:** * . .: : *. *:* : ...*: *** :. :* : : * *..** * *:*** * **::*** * * : *: *:* .:** .* ***:: **.* **: :::* *: * :*:. : .:: *:.*:*. ** * .* * *: . * .* . ** *:* *: : . :* :. . : : . : : : . . : :* . . : * . : : : : * : . : : : . :..: :.* *:. .* : :: ::* .* : : : : . . : ..: *.. : *:. . : . : . *.* : . : . :: : ** .:. : . :** **: *. :::. . . :. :.* *: :: . *: *:. :. :. : .* *:: *.. . *:: : ..* .: .* :.: *: . : . : . : : . . : . : .: ::.: : : : :: : **: : . .:: .* : . . : * : .: : :: *: * . :* .*:. :* ", "identical_positions": 210, "similar_positions": 324, "identity": "12.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110223-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZMX2-1", "uniprot_id": "A0A8I5ZMX2_RAT", "id": "A0A8I5ZMX2-1", "name": "", "aln": "-------------MVFLSLWLIAASLVEVRTSADGQAGAEEMVQIDLPTKRYREYELVTPVSTNLKGHYLSHILSANHKKRSPRDVSS-------------------------------NSEQLFFNVTAFGRDFHLRLRPNTHFIAPGAVVEWHETAPRPGNTTDPRNSRPHRSSSEGGWRSEPLQTSCAYVGDIMDVPGTSVAISNCDGLAGMIKSDNEEYFIEPLER-----------------GKQMDEENGRIHIVYKRSAMERAPRDVSEDVYYK----ESNLEGLDDLGTVYSNIGQQLNETTRRRRHAGENDYN----------IEVLLGVDDSVVRFHGKEHVQN-------YLLTLMNIVNEIYHDESLGVHINVVLVRMIMLGYAKSISLIERGNPSRSLENVCRWACQQQKSDPNHAEHHDHAIFLTRQDFGPAG-------MQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDETAMGSVMAPLVQAAFHRYHWSRCSGQELKRYIHS--YDCLLD-DPFEHDWPKLP--ELPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAAGKWCYKGHCMWKNANQQKQDGNWGSWTKFGSCSRTCGTGVRFRTRQCNNPTPINGGQDCPGVNFEYQLCNTEECQKHFEDFRAQQCQQRNSHFDYQNTKHHWLPHEHPDSKKRCHLYCQSKETGDVAYMKQLVHDGTRCSYKDPYSICVRGECVKVGCDKEIGSNKVEDKCGVCGGDNSHCRTVKGTFTRTPRKLG-------------------KTRGAFVLPKGAR---------------------------NISLAETRETKNVLAIKNQATGHYILNGKGEEAKSRTFIDLGVEWDYNIEDDIETLHTDGPLHDPVIVLIIPQENDTRSSLTYKYIIHEDSVPTINSNNVIQEELDTFEWALKSWSQCSKPCGGGFQYTKYGCRRKSDSKMVHRSFCEVNKKPKPIRRMCNIQECTHPLWAAEAWEHCSRSCGSSGYQLRTVRCLQPLQDGTNRSVHSRYCLGERPESRRPCNRIPCPAQWKTGPWNECSVTCGEGTEVRQVLCRTGDHCDGEKPESVRACQLPPCNDEPCLGDKSIFCQMEVLARYCSIPGYSELCCESCSKRSGTLPPPYLQEAAEIHSDAIFGPSDLPRSLVMPTPFLPYYSGSRADKKSLSSVSSVANPSAYAAFRSSSRAS-VSFPRKKAQEGGTKTP--VSMPPSSSIKTDHLHSSSPGAAAPSPAITDSIGASPQTRTPKKD-GKTISRRHPIRSTASER", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q287-1", "uniprot_id": "E9Q287_MOUSE", "id": "E9Q287-1", "name": "", "aln": "-------------MVFLSLWLIAASLVEVRTSADGQAGTDEMVQIDLPTKRYREYELVTPVSTNLKGHYLSHILSANHKKRSPRDVSS-------------------------------NSEHLFFNVTAFGRDFHLRLKPNTHFIAPGAVVEWHETAPRPGNTTDPRNSHLHGSASEGSWRSEPLQTSCAYVGDIMDIPGTSVAISNCDGLAGMIKSDDEEYFIEPLER-----------------GKQMDEENGRIHVVYKRSAVEQPPRDVSEDVYHR----ESDLEGLDDLGTVYSNIGQQLNKTMRRRRHTGENDYN----------IEVLLGVDDSVVRFHGKEHVQN-------YLLTLMNIVNEIYHDESLGVHINVVLVRMIMLGYAKSISLIERGNPSRSLENVCRWACQQQKTDPNHAEHHDHAIFLTRQDFGPAG-------MQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDETAMGSVMAPLVQAAFHRYHWSRCSGQELKRYIHS--YDCLLD-DPFEHDWPKLP--ELPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAAGKWCYKGHCMWKNANQQKQDGNWGSWTKFGSCSRTCGTGVRFRTRQCNNPTPINGGQDCPGVNFEYQLCNTEECQKHFEDFRAQQCQQRNSHFDYQNTKHHWLPHEHPDSKKRCHLYCQSKETGDVAYMKQLVHDGTRCSYKDPYSICVRGECVKVGCDREIGSNKVEDKCGVCGGDNSHCRTVKGTFTRTPRKLG-------------------KTRGAFVLPKGAR---------------------------NISLAETRETKNVLAIKNQATGHYILNGKGEEAKSRTFIDLGVEWDYNIEDDIETLHTDGPLHDPVIVLIIPQENDTRSSLTYKYIIHEDSVPTINSNNVIQEELDTFEWALKSWSQCSEPCGGGFQYTKYGCRRKSDSKMVHRSFCEVNKKPKPIRRMCNIQECTHPVWAADEWEHCSRSCGSSGNQLRTVRCLQPLQDGTNRSVHSKYCLGDRPESRRPCNRVPCPAQWKTGSWNECSVTCGEGTEVRQVLCRTGDHCDGEKPESVRPCQLPPCNDEPCLGDKSIFCQMEVLARYCSIPGYNKLCCESCSKRSGTLPPPYLQEAAEIHSDAIFGPSDLPRSLVMPTPFLPSSSGTRAEKKSLSSFSSMANPNADAAFRASSRAS-ADFPRKRAHQAGRKTL--ESVPSSSSIKTDHLRPASPVAAAPSPAISDSIGASPQTRTPKKDDAKSVSRRHPTRSTASER", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O15072-1", "uniprot_id": "ATS3_HUMAN", "id": "O15072-1", "name": "A disintegrin and metalloproteinase with thrombospondin motifs 3", "aln": "-------------MVLLSLWLIAAALVEVRTSADGQAGNEEMVQIDLPIKRYREYELVTPVSTNLEGRYLSHTLSASHKKRSARDVSS-------------------------------NPEQLFFNITAFGKDFHLRLKPNTQLVAPGAVVEWHETSLVPGNITDPINNHQPGSATYRIRRTEPLQTNCAYVGDIVDIPGTSVAISNCDGLAGMIKSDNEEYFIEPLER-----------------GKQMEEEKGRIHVVYKRSAVEQAPIDMSKDFHYR----ESDLEGLDDLGTVYGNIHQQLNETMRRRRHAGENDYN----------IEVLLGVDDSVVRFHGKEHVQN-------YLLTLMNIVNEIYHDESLGVHINVVLVRMIMLGYAKSISLIERGNPSRSLENVCRWASQQQRSDLNHSEHHDHAIFLTRQDFGPAG-------MQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDETAMGSVMAPLVQAAFHRYHWSRCSGQELKRYIHS--YDCLLD-DPFDHDWPKLP--ELPGINYSMDEQCRFDFGVGYKMCTAFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAAGKWCYKGHCMWKNANQQKQDGNWGSWTKFGSCSRTCGTGVRFRTRQCNNPMPINGGQDCPGVNFEYQLCNTEECQKHFEDFRAQQCQQRNSHFEYQNTKHHWLPYEHPDPKKRCHLYCQSKETGDVAYMKQLVHDGTHCSYKDPYSICVRGECVKVGCDKEIGSNKVEDKCGVCGGDNSHCRTVKGTFTRTPRKLG-------------------YLK-MFDIPPGAR---------------------------HVLIQEDEASPHILAIKNQATGHYILNGKGEEAKSRTFIDLGVEWDYNIEDDIESLHTDGPLHDPVIVLIIPQENDTRSSLTYKYIIHEDSVPTINSNNVIQEELDTFEWALKSWSQCSKPCGGGFQYTKYGCRRKSDNKMVHRSFCEANKKPKPIRRMCNIQECTHPLWVAEEWEHCTKTCGSSGYQLRTVRCLQPLLDGTNRSVHSKYCMGDRPESRRPCNRVPCPAQWKTGPWSECSVTCGEGTEVRQVLCRAGDHCDGEKPESVRACQLPPCNDEPCLGDKSIFCQMEVLARYCSIPGYNKLCCESCSKRSSTLPPPYLLEAAETHDDVISNPSDLPRSLVMPTSLVPYHSETPAKKMSLSSISSVGGPNAYAAFRPNSKPDGANLRQRSAQQAGSKTVRLVTVPSSPPTKRVHLSSASQMAAASFFAASDSIGASSQARTSKKD-GKIIDNRRPTRSSTLER", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JH43-1", "uniprot_id": "A0AC58JH43_DANRE", "id": "A0AC58JH43-1", "name": "", "aln": "-------------MVVLSLRLLIVGVVVSLTSAH-LAG-EIIDKEDLLKNRLKEYGLITPISTDAEGHFLSHFLSANHKQRVKRDVLEG---------------------------SAPAPDRLFFNITVFGKEFHLRLHPNQRLVAPGAMVEWHDDIEIAGNATDNR------THFERILKRELLKTDCTFIGDITDVPGASVAINNCDGLAGMIRTDSDEYFIEPLEQ-----------------GTQEHEERGRVHVVYRRSAVLQTPSDISLDYQPI----EPELD----TPRMLDNIAKQVNKTVRRRRHAGDEDYN----------IEILLGVDDSVVRFHGKEHVQN-------YLLTLMNIVNEIYHDESLEVHINVVLVRMIMLGYAKSISLIERGNPSRSLENVCRWAFVQQKEDPEHSEHHDHAIFLTRQGFGPTG-------MQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDETAMGSVMAPLVQAAFHRYHWSMCSGQELKRYIHS--YDCLLD-DPFKHDWPQLP--ELPGINYSMDEQCRFDFGVGYKICTSFRTFDPCKQLWCSHPDNPYFCKTKKGPPLDGTECAPGKWCYKGHCMWKNANQVKQDGAWGAWSKYGSCSRSCGMGVRFRTRQCNNPVPSNGGQDCPGVNYEYQLCNTDDCPKHFEDFRAQQCQLRNSHFEYQNAKHHWLPYEHPDANKRCHLYCQSKETGDVAYMKQLVHDGTRCSYKDPYSICVRGECVKVGCDREIGSNKVEDKCGVCGGDNSHCRTVKGTFTRVPKKAGKKLTKRSQKEIHVLENTIWKTRGAFLLPKGARNVYLNETADSRNVMGYLKMFLIPPGARHVIIQEHEASPQILAIKNQATGHYVLNGKGEDARSRRFIEMGVEWDYLVEEDVETLHTDGPLNDAIVVLIIPKDNETRSTLMYKYIIHEDSVP-LNNNNVIQED--TYEWALKSWSQCSRPCAGGFQYTKYGCRKKGDNKMVHRGYCDVNKKPKPIRRMCNLQDCTQPQWITEEWEHCTKTCGSLGYQIRTVRCVQFLHEGTNRSIHSKYCNGEKPEMRRACNRVACPAQWRTGAWSECSVSCGEGVSRRLVTCRIGDQCTGEKPESQKPCRPRPCHDEPCGGDKSIFCQMEVLARYCSIPGYNKLCCESCSRRSGTFAP-LLHEAAETEEELRFG----SASQLLETLSAAANGSLKVPQQHQRGSTSQGQFSKQAATPPPRKHNTENSKTQKRLKPSARNLPALSIHSSWS--------------------EDGVKDAPMQLESFQE------SQWPTTSSEVER", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1Z6-1", "uniprot_id": "Q9W1Z6_DROME", "id": "Q9W1Z6-1", "name": "", "aln": "MTVAAIGSNRHRRLALIVLTTLWLLIGASSSSSSTSSTNPKSVNIELRRKRSLHYNGIELDKNTLVGHLREHERALIFGSRSPEEAPEFKLVHLAQQRPEEQQRLEERKRPGEAEQHGGNPHQRRQRRSLPSEDGNGPLPPEEEEQEAGEDVEARLQLQQSPQLIDDAFIFIRRTENGTQFVEHSPQLLKRLERCFYRSPAAALDLCEPGNVRGVFQQNGSDLVIHPLPARFGTGTHVLYQARVDKSGGGYSEASSRRTASPLDSQLQFEPDAEEFNEPRRRLRAQSQLQSPLRLRFQPRHHHPHQHHQQRRRRYIGDAPRSRWSDIPEELFIETAIFVDSDLYAHMQKNFPTNTESKVVSFLLAMINGVQLLYHHPTLGRRINFVLKRLEIWKSWDPPGLVRSRDVENYLNSFCKWQEKLNPFSDADPLHYDHALVLTGLDLVTYDKGKANSQVVGMATVKGMCTSIYSCTINEAKHFESVFVVAHEIGHNLGMRHDAKEISC---DPTMHIMSPKLGSG--KVTWSKCSRTYLEDFLMDPQAECLFDRDSFAGPWDHTAGGRLPGERFNANQQCMLRFGKNFMQASTQSKMEICRDLHCRQDGLPWTS----HPALEGTECGPNMWCRGGTCEARSSKQ----GSYSALKSWPPEHIPEATHEKIIRHEPNRIPP------------------------LLHDYNPMDN-------ELPGSPSNWGEWSEPSACESGCLYGQSR---------RLLEGSTGLRTLNRSCLNFPSRCIGRDRRFVTCNTPQCHKVPVQTINDFATQVCMQARKSDPELTG-------------------EGQQ--------------------------------------LPSTLDASCKIFCRTRTNGTKSRRWTFPDGTTCKAKQHNPEDITYCISGRCERFSCDNSTSN--FFKMDSSFCEARSVRPTRDSSDQESRQQTNRQRYAERQEGKPQKNHYENEVAKRPSYGQGNHINAPASPYKRRNYHKPYPPEIPRPPPPAS--ASLIALDRSSSSESEWVAHPGCHSNCMTDSKGVQGVTSRLTGVESIQLCSYR-------IQPCERLQTAAEY-------AEQTCARYRQKVRGLSGHGAQISASIDEPDRSCRVG-CQDE-----------------------FIKYRYYLVNGRNGHFPPGTRCSPVGKRYCVYGRCLEFGDDDLPLDKTHISLGQLRTRRKRSSISNDLFNITEIFIKPSHSDISAENIEFTQPIHVSADELSSKSR-----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..: * : : :*: : : :* :* .* : .. *: .* : . .* .:. . ..: . : ..: : * *: . .* ** : . : * : . : : *.::: : : ..: *::: :..: .*.** * * .* * : * . : :.:*: : : :. ****: *: . ** : **..: . *:. * :**:::* *: :**. :* :**.** *: : .. .*:. : .. *:..*:* : . .. *:***:.** .: . . : * *.*.*** .: ***:*. . *.*.****** ** ***.**.: * . :*:* : :. : ** ** *: :: . :**:* *.* * : . .*** .:. ::** : ** .: .:: .:: *::* * : . *: . *.*:****... ** * * :.::* * :.: ..: . . . :: :: *. * :.*:.. : : .: :* ..*.. : ** **: :*:...* : .: . ..*: . .. .* * :: :. : . *. * : : :::. .. : : : .: . : * :. * : *.. : .. : .. ::** : .::* * :. :.: . : . . ...*. * :: : . : : : : * * ..: :. . * . .. : : *: : *.: . * :.*:*: .*:: .. :*.. . . * : .. *. :.*: *:** : : . *.. :.* ... . . : . . : .. . . . . . . : ", "identical_positions": 163, "similar_positions": 347, "identity": "12.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110303-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4AB26-1", "uniprot_id": "D4AB26_RAT", "id": "D4AB26-1", "name": "Structural maintenance of chromosomes protein 6", "aln": "----------------------MAKRKEENFCSPENAKRPRQEELEDFDKDGDEDECTISFTNGTSTLTAA----------------------------------EVGIIESIQLRNFMCHSMLGPFKFGSNVNFVVGNNGSGKSAVLTALIVGLGGKAVATNRGSSLKGFVKAGQNSADISITLRNRGDDAFRANVYGDSIVVQQHISVDGSRSYKLKSEKGTVVSTRKEELIAILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYKFFMKATQLEQMKEDYSYIMETKERTKEQINQGEERLTELKRQCLEKEERFQNIAGLSTMKTNLEYLKHEMAWAVVNEIEKQLNAIRDNIKIGEERAAKLDRKMEEQQVRLNDAEKKYKDIQDKLEKISEETNARAPECMALKTDVIARTRAFNDAEVLYNRSLNEYKALKKDGEQLCKRIEELKKSTDQS-LEPERLERQKRICWLKEKVKALQDQENTVNQEVEQFEQAIEKDKQEHVRIKREDVEVRHTLSYNQRQLKELKDSKTDRLKRFGPHVPALLEAIDDAYRRRQFTHKPIGPLGACIHLRD--PELALAIESCLKGLLQAYCCHNHADERVLQSLMKKFYPPGTSRPQIIVSEFRNEVYDVRLR--AAYHPEFPTVLTALEIDNAVVANSLIDMRSIETVLLIKNNSVARAVMQSQK--PPKNCREAFTADGDQVFAGRYYSSE---STRPKFLSRDVDSEISDLETEIENKKGHIMNLQHRLSALEKDIKRNEELLKRCQLHYKEIKMKIRKNISEIRELENIEEHQSVDIATLEDEAEENKIKMQMVEKNMEQQKENMENLKTLKIEAENKYDTIKLKINQLSELADPLKDELNLADSEVDSQKRGKQHYEDKQKEHMDTLNKKRRELDMKEKELQEKMSQARQICP----ERIEVKKSASILDKEINRLRQKIQAEHASHGD-REEIMKQYQEARETYLDLDSKVRTLRRFIKLLEEIMTHRYKTYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLSISVQPGEGNKASFNDMRALSGGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDMILKMADSQRFRQFILLTPQSMSSLPSS--KLIRILRMSDPERGQTTLPFRPVTQEEDDSAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q924W5-1", "uniprot_id": "SMC6_MOUSE", "id": "Q924W5-1", "name": "Structural maintenance of chromosomes protein 6", "aln": "----------------------MAKRKEENFCSPENAKRPRQEELEDFDKDGDEDECTISFTNGTSTLTAA----------------------------------EVGIIESIQLRNFMCHSMLGPFKFGSNVNFVVGNNGSGKSAVLTALIVGLGGKAVATNRGSSLKGFVKAGQNSADISITLRNRGDDAFRANVYGDSIVVQQHISVDGSRSYKLKSEKGTVVSTRKEELIAILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYKFFMKATQLEQMKEDYSYIMETKERTKEQINQGEERLTELKRQCLEKEERFQNIAGLSTMKTNLEYLKHEMAWAVVNEIEKQLNAIRDNIKIGEERAAKLDRKMEEQQVRLNDAEKKYKDIQDKLEKISEETNARAPECMALKTDVIARTRAFNDAEVLYNRSLNEYKALKKDGEQLCKRIEELKKSTDQS-LEPERLERQKRICWLKEKVKALQDQEHTVNQEAEQFEQAIEKDKQEHGRVRKEDIEVRHALNYNQRQLKELKDSKTDRLKRFGPHVPALLEAIDDAYRRRQFTHKPIGPLGACIHLRD--PELALAIESCLKGLLQAYCCHNHADERVLQSLMKKFYPPGTSRPQIIVSEFRDEVYDVRLR--AAYHPEFPTVLTALEIDNAVVANSLIDMRSIETVLLIKNNSVARAVMQSQK--PPKNCREAFTADGDQVFAGRYYSSE---STRPKFLSRDVDSEISDLETEIENKKGHIITLQQRLSALEKDIKRNEELLKRCQLHYKEIKMKIRKNISEIRELENIEEHQSVDIATLEDEAEENKIKMQMVEKNMEQQKENMENLKSLKIEAENKYDTIKLKINQLSELADPLKDELNLADSEVDSQKRGKQHYEDKQKEHLDTLNKKRRELDMKEKELQEKMSQARQICP----ERIEVKKSASILDKEINRLRQKIQAEHASHGD-REEIMKQYQEARETYLDLDNKVRTLRRFIKLLEEIMTHRYKTYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLSITVQPGEGNKASFNDMRALSGGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDMILKMADSQRFRQFILLTPQSMSSLPSS--KLIRILRMSDPERGQTTLPFRPVTQEEDDSAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96SB8-1", "uniprot_id": "SMC6_HUMAN", "id": "Q96SB8-1", "name": "Structural maintenance of chromosomes protein 6", "aln": "----------------------MAKRKEENFSSPKNAKRPRQEELEDFDKDGDEDECKG------TTLTAA----------------------------------EVGIIESIHLKNFMCHSMLGPFKFGSNVNFVVGNNGSGKSAVLTALIVGLGGRAVATNRGSSLKGFVKDGQNSADISITLRNRGDDAFKASVYGNSILIQQHISIDGSRSYKLKSATGSVVSTRKEELIAILDHFNIQVDNPVSVLTQEMSKQFLQSKNEGDKYKFFMKATQLEQMKEDYSYIMETKERTKEQIHQGEERLTELKRQCVEKEERFQSIAGLSTMKTNLESLKHEMAWAVVNEIEKQLNAIRDNIKIGEDRAARLDRKMEEQQVRLNEAEQKYKDIQDKLEKISEETNARAPECMALKADVVAKKRAYNEAEVLYNRSLNEYKALKKDDEQLCKRIEELKKSTDQS-LEPERLERQKKISWLKERVKAFQNQENSVNQEIEQFQQAIEKDKEEHGKIKREELDVKHALSYNQRQLKELKDSKTDRLKRFGPNVPALLEAIDDAYRQGHFTYKPVGPLGACIHLRD--PELALAIESCLKGLLQAYCCHNHADERVLQALMKRFYLPGTSRPPIIVSEFRNEIYDVRHR--AAYHPDFPTVLTALEIDNAVVANSLIDMRGIETVLLIKNNSVARAVMQSQK--PPKNCREAFTADGDQVFAGRYYSSE---NTRPKFLSRDVDSEISDLENEVENKTAQILNLQQHLSALEKDIKHNEELLKRCQLHYKELKMKIRKNISEIRELENIEEHQSVDIATLEDEAQENKSKMKMVEEHMEQQKENMEHLKSLKIEAENKYDAIKFKINQLSELADPLKDELNLADSEVDNQKRGKRHYEEKQKEHLDTLNKKKRELDMKEKELEEKMSQARQICP----ERIEVEKSASILDKEINRLRQKIQAEHASHGD-REEIMRQYQEARETYLDLDSKVRTLKKFIKLLGEIMEHRFKTYQQFRRCLTLRCKLYFDNLLSQRAYCGKMNFDHKNETLSISVQPGEGNKAAFNDMRALSGGERSFSTVCFILSLWSIAESPFRCLDEFDVYMDMVNRRIAMDLILKMADSQRFRQFILLTPQSMSSLPSS--KLIRILRMSDPERGQTTLPFRPVTQEEDDDQR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B5G4-1", "uniprot_id": "A0A8M2B5G4_DANRE", "id": "A0A8M2B5G4-1", "name": "Structural maintenance of chromosomes protein 6", "aln": "-----------MQGNGFGHLSAMNKRKSGVHNAVKPSKTPRTDGKTHVLEEEDVDEEDGALQDHLSASNVG----------------------------------DIGVIESITLRNFMSHHLLGPLKFGANVNFIVGNNGTGKSAILTALIVGLGGKATTTNRGTSLKGFVKYGETSTDIKVKLKNRGNDPYKGDVYGDSICIEHRITSDGCRTCKIKNKAGHVVSTKKEELTAILDHFGIQVDNPVSVLNQEMSKQFLHSKSEADKYRFFMKATLLEQMKRDYIHIKQTKAVTRDQVERQEECLRDLRQLFLQRKERYERMSSLDDMRQTLEDLKKKMAWSLVREKESQVEQLKEQIEK-EDADCKHEEKLQLCQNKVAVAEKKLQDSQKHLCTLREEQEHLTEESRKMKEEIKVKTKAQKSQEVVYFRAENKLKQLKKEQCLLQERIHKISHGSSRNRQEAEHMQHLKKISALKNQLEKLETESRALNQEIKDRQQALHKGREEYDKLSMEEKNIKASLESKSKRKKQLMASRSNRLRRFGDHMPELMESINKAFAQGRFKKKPVGPIGACISLKD--PTLTLAVECCLGFFLKSFCCDNYKDEKVLQGLMSQYFYKGN-RPQIMVCPFTDHVYNLQGR--GVHHPEFPSVLDCLNIENPVIANCLIDMRSIESILVIREKARARKVMQGSR--PPKNCREAFTADGDQVFTNRYYTPEH--EVLVKYLGGDPEAEISLVNGELENIQAQLLRFQLHSCSVKEDIQLMEEKLRSVIMACKKNQESINKVKASITELENIEEAQDEDISSLEEEAQENEQKIELEKRIVKEAEDELRKHEKGLLAVNQKFKDVKCKMEKLSDEMEQLKEEQVKAETVCNKLDQTMKTLEKKLKDHQNNIQSMKEDLSLQEEDLRDCEAKARELCP----ERQQVDQSPRSIDVEITRLRQKIKTQENSHGD-KEQIIREYAEAHSNYKSKSSQLRDLRKFIDRLDNIMIDRQDRYKTLRKSLSVRCKLYFNNFMIQLHCCGSMMFDHNNETLSISVKPPGQEMNSVSDMRSLSGGERSFSTVCFILALWEITESPFRCLDEFDVYMDMHNRSISMNMLVALSERQHLRQFIFITPQSISQLPKS--TNITIHQLQDPEKD---------TEEE-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCB8-1", "uniprot_id": "Q9VCB8_DROME", "id": "Q9VCB8-1", "name": "", "aln": "-----------MERSRRGRIRRMPSPGSESDGSTAEPTRKRSKQQFVAEAEPDFVEEETEKYANASTSQTARSRNKQARQTTLNMSQRSVNFNLTSELSIPNAFDRCGKVISMRLTNFMCHSNL-FIEFGPNINFLVGNNGSGKSAVITALALGLTSSARATNRASSIQKLIKNGEVSATISITLSNSGLRPFKADIFGPHLTVVRQIRHSSS-TYDLQDARGKSVSKKVSDIRRMLLCFGINVENPIFVLNQEAAREFLKELEPASNYKLLMKATQLDVCTSSLTECHALRRHFTQELEQLEKKKEMMIKHIAAEEEKLSILEDKEMVKENLQQCKTKLAWMAVTSYQNELNNLEHSIKLIENKKASLEQTTSKKESTQATMNQKLKEFEASKNQILATQKFQDERLKTAKKAVQDLLLEASQVKAKIGNAERRMREDQRSYDECEKLIGNYHADFNRVNEQRE--ENANKIEMLKKQVVKSEEIIAQLRAEQQEIKRDITSVQERLDAVKNGRIQLHKSKQNISWEIEALSRNKSNKLSVYGEQTIQVVHALRTQYAGSNMHRMPRGPLGQYISAPN--PKYRDLIENQLMHCLRSFIVGSDRERQSLRALLQNKFQGGN-MPTIITSPFTDRVYDVSRNKVQPTTPNTTVLIDEISCDDPVVMNYLIDILRIETVLVTESKEIAEFLTSDTENVPPNLTRVLVPNLGLEYIPSPNYAVYSTRITPARYIQKNVDDRIRQLQMEQSDLQEKEPSLEIDYMQHKKVLENTQKVISQKSTMIGQHQSRNQKAMQKIMELQNFDYQELPEYDRLKSHLADSGEKIEKCRLEREMLQEKLLSIQHRQTELESTEAEERRALEGINKKLTALDTEAGEVESKMRSLDLHYEENTRRFQKTLQLERKMLGEKETVLSELEKARTEAEKLG-----EFIATTQTEEKIREAISRYKSKIKQVEELNYN-PEELERGLAELRDELELQSRHLAVVDSVVKKLRMAYHQRAQLFQRSRHHYFTMVQFQFEQALAMRQFKVSFETSDKEKTWKINVFPPSGN--ETSNTRSLSGGERSFTTVSLLKGLWSTSDHPFYFLDEYDVFTDEVNRKFITEILIGEGLEWLSRQYCFLTPQDT-KVEAS--NLITVHKLEAPER-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12749-1", "uniprot_id": "SMC6_YEAST", "id": "Q12749-1", "name": "Structural maintenance of chromosomes protein 6", "aln": "MISTTISGKRPIEQVDDELLSLTAQQENEEQQQQRKRRRHQFAPMTQFNSNTLDEDSGFRSSSDVATADQDNFLEE----------------------------SPSGYIKKVILRNFMCHEHF-ELELGSRLNFIVGNNGSGKSAILTAITIGLGAKASETNRGSSLKDLIREGCYSAKIILHLDNSKYGAYQQGIFGNEIIVERIIKRDGPASFSLRSENGKEISNKKKDIQTVVDYFSVPVSNPMCFLSQDAARSFLTASTSQDKYSHFMKGTLLQEITENLLYASAIHDSAQENMALHLENLKSLKAEYEDAKKLLRELNQTSDLNERKMLLQAKSLWIDVAHNTDACKNLENEISGIQQKVDEVTEKIRNRQEKIERYTSDGTTIEAQIDAKVIYVNEKDSEHQNARELLRDVKSRFEKEKSNQAEAQSNIDQGRKKVDALNKTIAHLEEELTKE-MGGDKDQMRQELEQLEKANEKLREVNNSLVVSLQDVK---NEERDIQHERESELRTISRSIQNKKVELQNIAKGNDTFLMNFDRNMDRLLRTIEQRK--NEFETPAIGPLGSLVTIRKGFEKWTRSIQRAISSSLNAFVVSNPKDNRLFRDIMRSCGIRSN----IPIVTYCLSQFDYSKG---RAHGNYPTIVDALEFSKPEIECLFVDLSRIERIVLIEDKNEARNFLQRNPVNVNMALSLRDRRSGFQLSGGYRLDTVTYQDKIRLKVNSSSDNGTQYLKDLIEQETKELQNIRDRYEEKLSEVRSRLKEIDG-RLKSTKNEMRKTNFRMTELKMNVGKVVDTGILNSKINERKNQEQAIASYEAAKEELGLKIEQIAQEAQPIKEQYDSTKLALVEAQDELQQLKEDINSRQSKIQKYKDDTIYYEDKKKVYLENIKKIEVNVAALKEGIQRQIQNACAFCSKERIENVDLPDTQEEIKRELDKVSRMIQKAEKSLGLSQEEVIALFEKCRNKYKEGQKKYMEIDEALNRLHNSLKARDQNYKNAEKGTCFDADMDFRASLKVRKFSGNLSFIKDTKSLEIYILTTNDE--KARNVDTLSGGEKSFSQMALLLATWKPMRSRIIALDEFDVFMDQVNRKIGTTLIVKKLKDIARTQTIIITPQDIGKIADIDSSGVSIHRMRDPERQNNSNFYN-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : : :: * : .: * ***.* : :::*..:**:*****:****::**: :** . * ***.:*:: ::: * *: * : * * .:: .::* : : : * .. : .::. * :*.: .:: :: *.: *.**: .*.*: ::.** .:* :**.* *: . . : ::: : : :: : . :. : : * * . : :...*. :: .. : .. : : . : : .. : .: . ::. : * . : : : :.: *:: . : . :: : . :: : : . . . : : .. * :. : ::.:: .: . **:* : . :: : *.:: . :.: :: :: .. * : :: : . :: :. ... : ::*: ** ::: ..: *. . . * : . : . : :: .: . :. . :. : : : : : ::: . : .. :. : . : :: :. : : .. *. : :: . . : : : .. : . :. :* : * .: : : : *: . *:: : :. . : : :. * * . :: .: .: * : .: .. :: .* : . : : :*****:**: :.:: . *. : ***:**: * ** : ::: * ::***. .: . : : :: **: ", "identical_positions": 96, "similar_positions": 320, "identity": "8.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110304-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q32P44-1", "uniprot_id": "EMAL3_HUMAN", "id": "Q32P44-1", "name": "Echinoderm microtubule-associated protein-like 3", "aln": "MDGAAGPGDGPAREA-------LQSLSQRLRVQEQEMELVKAALAEALRLLRLQVPPSSLQGSGTPAP---------------------------------PGDS-LAAPPG-------LPPTCTPSLVSRGTQTE------TEVELKSSPGPPGLSNGPPAPQGA------------SEEPSGTQ------------------------------SEGGGSSSSGAGSPGPP---------GILRPLQPPQRADTPRRNSSSSSSPSERPRQKLSRKAISSANLLVRSGSTESRGGKDPLSSPGGPGSRRSNYNLEGISVKMFLRGRPITMYIPSGIRSLEELPSGPPPETLSLDWVYGYRGRDSRSNLFVLRSGEVVYFIACVVVLYRPGGGPGGPGGGGQRHYRGHTDCVRCLAVHPDGVRVASGQTAGVDKDGKPLQPVVHIWDSETLLKLQEIGLGAFERGVGALAFSAADQGAFLCVVDDSNEHMLSVWDCSRGMKLAEIKSTNDSVLAVGFNPRDSSCIVTSGKSHVHFWNWSGGVGVPGNGTLTRKQGVFGKYKKPKFIPCFVFLPDGDILTGDSEGNILTWGRSPSDSKTPGRGGAKETYGIVAQAHAHEGSIFALCLRRDGTVLSGGGRDRRLVQWGPGLVALQEAEIPEHFGAVRAIAEGLGSELLVGTTKNALLRGDLAQGFSPVIQGHTDELWGLCTHPSQNRFLTCGHDRQLCLWDGESHALAWSIDLKETGLCADFHPSGAVVAVGLNTGRWLVLDTETREIVSDVIDGNEQLSVVRYSPDGLYLAIGSHDNVIYIYSVSSDGAKSSRFGRCMGHSSFITHLDWSKDGNFIMSNSGDYEILYWDVAGGCKQLKNRYESRDREWATYTCVLGFHVYGVWPDGSDGTDINSLCRSHNERVVAVADDFCKVHLFQYPCARAKAPSRMYGGHGSHVTSVRFTHDDSHLVSLGGKDASIFQWRVLGAGGAGPAPATPSRTPSLSPASSLDV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VC03-1", "uniprot_id": "EMAL3_MOUSE", "id": "Q8VC03-1", "name": "Echinoderm microtubule-associated protein-like 3", "aln": "MDGAAGPGEGPAHET-------LQTLSQRLRVQEEEMELVKAALAEALRLLRLHGSTTTLQGSGISAP---------------------------------TRNSSITVPPG-------LPPTCSPSLVTRGTQTE------EELEIVPSSGPPGLSNGPPALQGG------------SEEPSGTQ------------------------------SEGGCSSSSGAGSPGPP---------GILRPVQPLQRSDTPRRNSSSSSSPSERPRQKLSRKAASSANLLLRSGSTESRGNKDPLSSPGGPGSRRSNYNLEGISVKMFLRGRPITMYIPSGIRSLEELPSGPPPETLSLDWVYGYRGRDSRSNLFVLRSGEVVYFIACVVVLYRPGGGPGGPGGGGQRHYRGHTDCVRCLAVHPDGVRVASGQTAGVDKDGKPLQPVVHIWDSETLLKLQEIGLGAFERGVGALAFSAADQGAFLCVVDDSNEHMLSVWDCSRGVKLAEIKSTNDSVLAVGFSPRDSSCIVTSGKSHVHFWNWSGGTGAPGNGLLARKQGVFGKYKKPKFIPCFVFLPDGDILTGDSEGNILTWGRSVSDSKTPGRGGAKETYTIVAQAHAHEGSIFALCLRRDGTVLSGGGRDRRLVQWGPGLVALQEAEIPEHFGAVRAIAEGLGSELLVGTTKNALLRGDLAQGFSPVIQGHTDELWGLCTHPSQNRFLTCGHDRQLCLWDGEGHALAWSMDLKETGLCADFHPSGAVVVVGLNTGRWLVLDTETREIVSDVTDGNEQLSVVRYSPDGLYLAIGSHDNMIYIYSVSSCGTKSSRFGRCMGHSSFITHLDWSKDGNFIMSNSGDYEILYWDVAGGCKLLRNRYESRDREWATYTCVLGFHVYGVWPDGSDGTDINSLCRSHNERVVAVADDFCKVHLFQYPCARAKAPSRMYSGHGSHVTSVRFTHDDSYLVSLGGKDASIFQWRVLGAGSSGPAPATPSRTPSLSPASSLDV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B7P6-1", "uniprot_id": "A0ACD6B7P6_DANRE", "id": "A0ACD6B7P6-1", "name": "", "aln": "MDGSTNSLDDVSAESSTEYPDKLSTMEVRLQAQEDEITLLKSSLADALRRLRLHDQQIPLLKQQLIAVNPAAARVLNQSCYVDGFSKPCRLSTSSLDGFNHTPNSLISNTAENGEGGAKTIPSHKPSTSERCTQTDPWIPNHESFPLALTRRVQSLSLEDALLEGTPFTDEIQTKEEDADEDEGKKDQTWSSIVEDTIQPTTIRTLQQQHSKSSEDSQGSCPQTPTSSSPAPPKEPTSSPHGGPLSPIQEGEK-TLARRNSEKWKEPQDKTKQRLSKKAASSTNLLTRSPSLESR-AKDLIASAGSQGSRRGTQNQS---IKMFIRGRPITMYIPSNIQNYEELKMDLPSQKLDLDWVYGYRGRDCRANLYLLPSGEAVYFIACVVVLYHISNQK-------QRHYRKHTDCVRCLAIHPDKVRVASGQTAGVDKDGKPLQPFVHIWDSKTLVTLQQIGLGIFERGVGAIAFSNSDGGTFLCVIDDSNEHMLSVWDWNKNIKQAEVKSTNEAVLAVDFSPTDTNNIISCGKSHVYFWTMSAGT-------MTKKQGIFGKYKKPKFVLCFVFSLTGDVLTGDSEGNILTWGKSAADIKTLGKG-AKETFQIMKQTRAHEGSVFTMCILQGGAILSGGGKDRKIIRWSADLAPERECEIPEKFGAVRTIADLDGEELLVGTTRNAILRGTFSDGFVAIVQGHVDEMWGLATHPTQNIFVTCGNDRQLCVWNAEDHRLDWCTTLEDSGLCADFCPNGAVVSVGLSTARWVVLDLQTKEVVADLIDGNEQLSVMRYSPDGSFLAVGSHDNFIYIYSVTEGGRRYTRFGKCTGHSSFITHLDWSKDGKFIMSNSGDYEILYWDVASGCKLLRNRFESKDREWASYTCVLGFHVMGVWLEGSDGTDINALCRSHSERMVAVADDFCKVHLFQYPCPKPKAPSYKYEGHGSHVTNVRFTHNDSHLLSLGGKDTCILQWRMKGAGTAEPKEHSAAASPPENGT-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***::.. :. : *: *.::. **:.**:*: *:*::**:*** ***: .* . * . :* :: .. *: .** * ***: .. : : .** . :* ::* .*.: *:*. ..:. :.**.** * * *:* :: .****.. ..*.::.:*:**:** **:*** ** * *** ** ::*.*. ****.. * . :***:***********.*:. *** . *.:.*.***********.*:**::* ***.***********: .. ***** *********:*** ********************.******:**:.**:**** *******:*** :* *:****:************ .:.:* **:****::****.*.* *:. *::.*****:**. *.*. :::***:*********: **** **:*************:* :* ** *:* ****: *: *::*****:*::*: :.*::*****:**::::*...*.. :*.****:*****:**: *.*******:**:*** :::** .::***.**:***.***:** *:***:*****:*:.*.* * *. *:::****** *.**** ***.*.**:*** :*:*:*:*: ********:****** :**:*****.******:. * : :***:* ***************:*****************.*** *:**:**:*****:********* *** :********:*****.**:*****************.:.**** * *******.*****:**:*:******:.*:***: *** : * :.: :*. . : ", "identical_positions": 522, "similar_positions": 228, "identity": "52.15%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110304-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N2H9-1", "uniprot_id": "PELI3_HUMAN", "id": "Q8N2H9-1", "name": "E3 ubiquitin-protein ligase pellino homolog 3", "aln": "MVLEGNPEVGSPRTSDLQHR---GNKGSCVLSSPGE--DAQPGE--EPIKYGELIVLGCCEEGGEETEAQRGEVTGPRAHSCYNGCLASGDKGRRRSRLALSRRSHANGVKPDVMHHISTPLVSKALSNRGQHSISYTLSRSHSVIVEYTHDSDTDMFQIGRSTENMIDFVVTDTSPGGGAAEGP---------SAQSTISRYACRILCDRRPPYTARIYAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLVMHPAGGFSEDSAP-GVWREISVCGNVYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGATLLWRTPAGLLRAPTLKQLEAQRQEANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYVRCGHVHGYHGWGCRRERG-----------------PQERECPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGHVCSEKTARYWAQTPLPHGTHAFHAACPFCGAWLTGEHGCVRLIFQGPLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BXR6-1", "uniprot_id": "PELI3_MOUSE", "id": "Q8BXR6-1", "name": "E3 ubiquitin-protein ligase pellino homolog 3", "aln": "MVLEGNPDVGSPRTSDLQHP---GSQGSCILSCPGE--EALAGE--EPIKYGELIVLG------------------------YNGCLASGDKGRRRSRLALSRRPHANGVKPDVMHHISTPLVSKALSNRGQHSISFTLSRSHSVIVEYTHDSDKDMFQIGRSTENMIDFVVTDTSPGGGATEGP---------SAQSTISRYACRILCDRRPPYTARIYAAGFDASSNIFLGERAAKWRTPDGLMDGLTTNGVLVMHPAGGFSEDSAP-GVWREISVCGNVYTLRDSRSAQQRGKLVENESNVLQDGSLIDLCGATLLWRTPAGLLRAPTLKQLEAQRQEANAARPQCPVGLSTLAFPSPARGRTAPDKQQPWVYVRCGHVHGYHGWGCRRERG-----------------PQERECPLCRLVGPYVPLWLGQEAGLCLDPGPPSHAFAPCGHVCSEKTARYWAQTPLPHGTHAFHAACPFCGAWLTGELGCVRLIFQGPLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F7M5-1", "uniprot_id": "E7F7M5_DANRE", "id": "E7F7M5-1", "name": "", "aln": "MVLEGSSEALCPPPSLELRPSCNKNQSSPPLGSGSQSHDALCPEDKEPIKYGELIVLG------------------------HNGSLASGDKGRRRSRLALYKRPKANGVKPDVIHNVSTPLVSKALSNKSQHSISYTLSRSHSVIVEYTHDPNTDMFQIGRSTESMIDFVVTDTASSGGGGQGQGGAGGEGGQSAQSTISRYACRIMCERSAPYTARIYAAGFDSSKNIFLGERAAKWRTSDGLMDGLTTNGVLVMHPAGEFVSEPAP-GVWREISVCGNVFALRETRSAQQRGKLVENESNMLQDGSLIDLCGATLLWRTPSGLRHTPTLKQLESLRQELNAARPQCPVGFNTLAFPSLAQ-RATIDKKQPWVYMNCGHVHGYHNWGFRKEKAGVAAVALTGGGGTAPATTGERECPMCRGVGPYVPLWLGCEGGLYLDAGPPTHAFCPCGHVCSEKTVQGWSQIPLPHGTHAFHAACPFCGTWLTGEQGYIKLIFQGPVD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O77237-1", "uniprot_id": "PELI_DROME", "id": "O77237-1", "name": "Protein pellino", "aln": "MVKRTDG------------------TESPILAEDGG--DGHDKP---RLRYGELVILG------------------------YNGYLPQGDRGRRRSKFVLHKRTEASGVKRSKHYIVQSPQTSKAILDANQHSISYTLSRNQAVIVEYKEDTETDMFQVGRSSESPIDFVVMDTLPGDKKDAK----------VMQSTISRFACRILVNRCEPAKARIFAAGFDSSRNIFLGEKATKWQD-NVEIDGLTTNGVLIMHPKGSFCGGNAKCGLWRECSVGGDVFSLRESRSAQQKGQPIYDECNILQDGTLIDLCGATLLWRSAEGLQHSPTKHDLEKLIDAINAGRPQCPVGLNTLVIPRKVNIGDQVN--QPYVYLNCGHVQGHHDWGQDENTG-------------------ARRCPMCLELGPVVTLCMGLEPAFYVDVGAPTYAFNPCGHMATEKTVKYWANVEIPHGTNGFQAVCPFCATPLDGATGYIKLIFQDNLD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . . * *. . :. ::****::** :** *..**:*****::.* :*..*.*** . : :.:* .***: : .*****:****.::*****..*.:.****:***:*. ***** ** ... ******:****: :* * .***:*****:* ******:*:**: : :*********:*** * * * *:*** ** *:*::**::*****:*: : :*.*:****:************:. ** ::** ::** : **.*******:.**.:* .. : **:**:.****:*:*.** .: . *.**:* :** *.* :* * .: :* *.*::** ****:.:***.: *:: :****:.*:*.****.: * * * ::****. :*", "identical_positions": 210, "similar_positions": 123, "identity": "41.75%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110307-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C6T2-1", "uniprot_id": "OST4_HUMAN", "id": "P0C6T2-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4", "aln": "MITDVQLAIFANMLGVSLFLLVVLYHYVAVNNPKKQE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99LX8-1", "uniprot_id": "OST4_MOUSE", "id": "Q99LX8-1", "name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4", "aln": "MITDVQLAIFANMLGVSLFLLVVLYHYVAVNNPKKQE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "H0WEU8-1", "uniprot_id": "H0WEU8_DANRE", "id": "H0WEU8-1", "name": "", "aln": "MVTDVQLAIFANMLGVSLFLLVVLYHYVAVNNPKKLE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:********************************* *", "identical_positions": 35, "similar_positions": 1, "identity": "94.59%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110307-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NUQ4-1", "uniprot_id": "TM214_HUMAN", "id": "Q6NUQ4-1", "name": "Transmembrane protein 214", "aln": "MATKTAGVGRWEVVKKGRRPGVGAGAGGRGGGRNRRALGEANGVWKYDLTPAIQTTSTLYERGFENIMKRQNKEQVPPPAVEP-KKPGNKKQPKKVATPPNQNQKQGRFRSLEEALKALDVADLQKELDKSQSVFSGNPSIWLKDLASYLNYKLQAPLSEPTLSQHTHDYPYSLVSRELRGIIRGLLAKAAGSLELFFDHCLFTMLQELDKTPGESLHGYRICIQAILQDKPKIATANLGKFLELLRSHQSRPAKCLTIMWALGQAGFANLTEGLKVWLGIMLPVLGIKSLSPFAITYLDRLLLMHPNLTKGFGMIGPKDFFPLLDFAYMPNNSLTPSLQEQLCQLYPRLKVLAFGAKPDSTLHTYFPSFLSRATPSCPPEMKKELLSSLTECLTVDPLSASVWRQLYPKHLSQSSLLLEHLLSSWEQIPKKVQKSLQETIQSLKLTNQELLRKGSSNNQDVVTCDMACKGLLQQVQGPRLPWTRLLLLLLVFAVGFLCHDLRSHSSFQASLTGRLLRSSGFLPASQQACAKLYSYSLQGYSWLGETLPLWGSHLLTVVRPSLQLAWAHTNATVSFLSAHCASHLAWFGDSLTSLSQRLQIQLPDSVNQLLRYLRELPLLFHQNVLLPLWHLLLEALAWAQEHCHEACRGEVTWDCMKTQLSEAVHWTWLCLQDITVAFLDWALALISQQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BM55-1", "uniprot_id": "TM214_MOUSE", "id": "Q8BM55-1", "name": "Transmembrane protein 214", "aln": "MAARSAGSGGWEVVKRGRRPGASSGGRGGGGGSDRRALGEANGVLKYDLSSPIQTTSTLYERGFEKIMKRQNKEQVPPPAAES-KKPINKKQPKKVTAVPSQNQKQGPFRRLEDALKALDVAALQKELDKSQSVFTGNPSVWLKDLASYLNYKLQTPRMEPTLSQYPHDYPYSLVSRELRGIIRGLLTKAAGSVELFFDHCLFTMLQELDKTPGESLHGYRICIQAVLQDKPKIVTSNLDKFLELLRSHQSRPAKCLTIMWALGQAGFTNLTEGLKVWLGIMLPVLGIKALSPFAIAYLDRLLLMHPNLTKGFGMIGPKDFFPLLDFAYMPNNSLSPSLQEQLCQLFPRLKVLAFGAKPESSLHTYFPSFLSRATPSCPAAMKKELLASLTQCLTVDPLSTSVWRQLYPKHLSQSSLLLEHLLKSWEHIPKKARKSLQETIQSLKVTNQELLKKGSGGSEHVLTCDTACKGLLQRARGPRPPWARLFLLLLVFAVGFLCHDLRSNSSLQASLTGRLLRSSGLLPVGQQVCARLSSYSLQSYNWLQETLPACGSHLLAVVQPSLQLAWTHIYAIFSFLSAHCASYLACFSDSLAGFFQR--VQLPEALQQLFHALKELLLLFCHSVLLPTWHLLLAALAQVQEHCHEACRGDVTWDCIKTQLSRAAQWTWLCLQDVTVAFLDWALTMISQQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QEL0-1", "uniprot_id": "F1QEL0_DANRE", "id": "F1QEL0-1", "name": "", "aln": "MAS---GVGKWEVVKKGKK--ATSSSKTQDKKSARKALREAN-------TDSNHVMSETIFDGFEKMVKKQNKEQVPPPVETQQKKPNAGKQTKKP--PANSSPKPVHYKTLEEAVKALNIAELKQQLEKSQTLFPENPSIWVKDLAGYLNYKLPAPDTDPTLSSYAHDYPYCLAGKELKAIIKNLLGKCSDALPEFFDHCVFTMLREQDRQPSDPLHGYRMCIQALMQDKPKIATLNLSDHLELLRSHQNRPLKCLTIMWALGQAGFYDLSQGIRVWLGIMLPVLGMKALSAYAIAYLERLLTLHANLTKGFGIMGPKEFFPLLDFAYMPKNALSQSLQEQLCRLYPRIKVLAFGAKPESTLHTYFPSFLSRATPNCPGAMKKELLRSLTECLSVDSQSLSVWRQLYTKHLPQSSLLLNHLLKTWKTLPLKLQKSLQDTIQSFRVTNDELQS--GAHTQEISDCNSLCQSLQLKMHGQSVPWWRVLLMLLVCVLGFVAHDVRTQGSFSDSRTAVFLEQLGVSGASQQAWSRVSHYSQQSLSWLSENTPYYYSSAVTAVRPLLEYGQEYVKLAVLKIAHMSSELMLWMQENLPLLLHWIHANTPESVFQFLEFLKGLLLFVHEQMILPALHYLNTALQLAWRSLQESCNGEVSLHCLQDHVRSFTNSTWIYLQDATSAIKSRAQELLS--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: * * *****:*:: . :.. . *:** *** : . :. * ***:::*:*********. *** **.** .... * :: **:*:***::* *:::*:***::*. ***:*:****.****** :* :****.:.*****.*..:**:.**:.** *.:.:: *****:****:* *: *.:.*****:****::******.* **...********.** ************** :*::*::***********:*:**.:**:**:*** :*.*******::***:***********:*:*: *******:*:**:*********:*:**************.** ****** ***:**:**. * *******.***.******:***.:*: :* * :****:****:::**:** .. .:.: *: *:.* : :* ** *::*:*** .:**:.**:*::.*:. * *. :*.. *. ..**. ::: ** *. .** *. * * ::.*:* *: . : . :: .:. : : :.*. : : : *::: *::. *: * *:. ..::** * * ** . . :*:*.*:*: .*:: :: .: **: *** * *: . * ::* ", "identical_positions": 328, "similar_positions": 204, "identity": "47.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110309-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48060-1", "uniprot_id": "GLIP1_HUMAN", "id": "P48060-1", "name": "Glioma pathogenesis-related protein 1", "aln": "-MRVTLAT-IAWMVS-------------------FVSNYSHTANILPDIENEDFIKDCVRIHNKFRS---EVKPTASDMLYMTWDPALAQIAKAWASNCQFSHNTR-LKPPHKLHPNFTSLGENIWTG-SVPIFSVSSAITNWYDEIQDYDFKTRICKK--VCGHYTQVVWADSYKVGCAVQFCPKVSGFDALS--NGAHFICNYGPGGNYP-TWPYKRGA-TCSACPNNDKCLDN-LCVNRQRDQVKR---------YYSVVYPGWPIYP---RNRYTSLFLIVNSVILILSVIITILVQHKYPNLVLLD-----------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CWG1-1", "uniprot_id": "GLIP1_MOUSE", "id": "Q9CWG1-1", "name": "Glioma pathogenesis-related protein 1", "aln": "-MQVILAV-IVWMAS-------------------SVSSSSFTASTLPDITNEDFIKECVQVHNQLRS---KVSPPARNMLYMSWDPKLAQIAKAWTKSCEFKHNPQ-LHS--RIHPNFTALGENIWLG-SLSIFSVSSAISAWYEEIKHYDFSTRKCRH--VCGHYTQVVWADSYKLGCAVQLCP-----------NGANFICDYGPAGNYP-TWPYKQGA-TCSDCPKDDKCLNS-LCINPRRDQVSR---------YYSVDYPDWPIYL---RNRYTSLFLIAKSVLLLLSVIITIWVKHKYPNLVLLD-----------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R4P4-1", "uniprot_id": "M0R4P4_RAT", "id": "M0R4P4-1", "name": "", "aln": "-MKASLPLSVVWRAQSNSIRLRGVLKLWLCELWLLLMSSGLNAK-LPLEEDVDFINEYVNLHNELRG---TVFPPGVNLRFMTWDVALSRTARAWGKKCVFERNTH-LDKVHESHPVFTDIGENMWVG-PEKDFTATNAIRSWHEERKSYNYVNDTCIEDEDCSHYIQLVWDHSYKVGCAVTPCAKVG---AIT--YAALFICNYAPGGTLT-RRPYQAGQ-FCSRCTNEEKCIDF-LCGNADRDEAA----------YYQFWYPPWETPRPLVCNRLCFFVLFMRLASLGLCVIIVMIIQNRFPVVLTESPMIMSVEE--GVNTEDEIVVEEGE------------EEIQEE----EDEQ---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQ35-1", "uniprot_id": "GRPL2_MOUSE", "id": "Q9CQ35-1", "name": "GLIPR1-like protein 2", "aln": "-MKASLPWSVVWRAQSNYVRLRRVLK--LCELWLLLVGSGLNAK-LPLEEDVDFINEYVGLHNELRG---TVFPPGVNLRFMTWDVALSRTARAWGKKCMYSRNTH-LDKLHESHPVFTEIGENMWVG-PVEDFTVTTAIRSWHEERKSYSYLNDTCVEDQNCSHYIQLVWDSSYKVGCAVTSCARAG---GFT--HAALFICNYAPGGTLT-RRPYQAGQ-FCSRCGPGDQCTDY-LCSNTVRDEAT----------YYQFWYPPWEKPRPVVCNPMCIFILFLRVASLLLCVIVVLIVQSRFPVILMETPTIISAEE--EGKTEVEIVMEEGEGEGEGGEGEGEGEEKEEEEMLEEDEQ---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4G1C9-1", "uniprot_id": "GRPL2_HUMAN", "id": "Q4G1C9-1", "name": "GLIPR1-like protein 2", "aln": "-MEAARPFAREWRAQSLPLAVGGVLKLRLCELWLLLLGSSLNARFLPDEEDVDFINEYVNLHNELRG---DVIPRGSNLRFMTWDVALSRTARAWGKKCLFTHNIY-LQDVQMVHPKFYGIGENMWVG-PENEFTASIAIRSWHAEKKMYNFENGSCSG--DCSNYIQLVWDHSYKVGCAVTPCSKIG---HII--HAAIFICNYAPGGTLT-RRPYEPGI-FCTRCGRRDKCTDF-LCSNADRDQAT----------YYRFWYPKWEMPRPVVCDPLCTFILLLRILCFILCVITVLIVQSQFPNILLEQQMIFTPEESEAGNEEEEKEEEKKEKEEMEMEIMEMEEEKEEREEEEEETQKEKMEEEEK------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YY67-1", "uniprot_id": "A0A8M6YY67_DANRE", "id": "A0A8M6YY67-1", "name": "", "aln": "-MSSCFQLLISAC---------------------FLLG-VFSSEYLFDITDRAFIDECVREHNQNRS---SVSPTAANMRYMTWDAALAVTARAWARFCLFKHNIH-LREAKRVHPTFTTVGENIWAGAPYSRFTVKSAVFSWVNELKDYNYNNNQCNDKKVCGHYTQVVWADSYKVGCAVQTCPNGVAETHFSNIQGVIFVCNYATAGNFAGRSPYKQGA-SCSGCGGSDKCERN-LCRNTDRDAEQS---------YN--WTPDWDPALS-SCGTFCVSVMIIRLISVVLLFVCVHFLQCRYSPFIYD------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9DAG6-1", "uniprot_id": "GPRL1_MOUSE", "id": "Q9DAG6-1", "name": "GLIPR1-like protein 1", "aln": "-MALKKKLNFLWTLVLYLIA------------SRLPKAFGKDLPRVPTITDPKFIDAFLNIHNELRR---KVQPPAADMNQLFWDQQLAKLAKAWTRECKLAHNPC-IKQRYECLEDYDFIGENIYLG-RIETQ-PEDVVINWYNESKYFNFDFNTCSE--MCGHYTQVVWAKTVKIGCAVSNCPNLKG------FSAGLFVCNYSPAGNFIGFRPYTRGD-SCSMCG-QKTCENS-LCRP----------------------MNRKTPHHKAACHVLVLGFILQSLL----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A1W2P7V2-1", "uniprot_id": "A0A1W2P7V2_MOUSE", "id": "A0A1W2P7V2-1", "name": "", "aln": "-MALKKKLNFLWTLALYLIA------------TRLPKAFGNDLPRVPSILDPKFIDAFLNIHNELRR---KVQPPAADMNQVIWDQKLAKLAKAWTRECKLGHNPC-TSKQYGCLLDYDFIGENIYLG-EIETQ-PEDVVNNWYNENTDYNFVDNTCSK--ICRNYTQVFWAKTFKIGCAVSNCPNLTR------YSAGLFVCNYSPTGNFLDFRPYRKGD-PCSMCG-QRKCENS-LCRP----------------------MNRKTPHQKAACHVLVLGFILQRLL----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZI91-1", "uniprot_id": "D3ZI91_RAT", "id": "D3ZI91-1", "name": "", "aln": "-MALKKKLIFLWTLALYLVA------------SRLPKAFGKVLPRVPTINDPEFKNGFLNSHNEARR---KVQPPASNMNQLSWDKSLAKLAKSWTRECKFSHNPC-TSKRHGCTKDYDYIGENIYLG-KIDAR-PEDVVFSWYNETKDYNFDDNTCTK--TCGHYTQVVWAKTLKIGCAISNCPHLTG------YSAGLFVCNYVPAGNFQGSKPYIKGE-PCSMCG-EKECVNS-LCSH----------------------TMGRASQQK-TCHLLVLGFILQRLI----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6UWM5-1", "uniprot_id": "GPRL1_HUMAN", "id": "Q6UWM5-1", "name": "GLIPR1-like protein 1", "aln": "-MALKNKFSCLWILGLCLVA------------TTS--------SKIPSITDPHFIDNCIEAHNEWRG---KVNPPAADMKYMIWDKGLAKMAKAWANQCKFEHNDC-LDKSYKCYAAFEYVGENIWLG-GIKSFTPRHAITAWYNETQFYDFDSLSCSR--VCGHYTQLVWANSFYVGCAVAMCPNLGG------ASTAIFVCNYGPAGNFANMPPYVRGE-SCSLCSKEEKCVKN-LCRTPQLIIPNQ---------NPFLKPTGRAPQQT-AFNPFSLGFLLLRIF----------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFY2-1", "uniprot_id": "Q9VFY2_DROME", "id": "Q9VFY2-1", "name": "SCP domain-containing protein", "aln": "MMQPSAVLLTTIMIISCEVA--------------FACNGKIIASGITAEERSIILQEHNRLRQIVATGRYPGQPGAENMREIVWDDELAARAQKWADNCQFRHDPHRTINRFTMGQNLAIIWSTAPLD--ADDGDFPSRIQSWFNEVQKYSFGDAWSPK---TGHYSQLVWGETSLVGCGYAEYKDTSK-------YNKLYVCNYGPGGNVVGYNPYEVGKPSCSTYGMKPSSRYQGLCAAPGSSPAANSVYGANTIETYEYGYNSSPSSQTANNNPPTNNINKSQFSYNQPRPKPVQTINPNPSPFNPQAAVPSASTFGGSSFGSASRGGSHAYTTDPSQSAGRYKHKLEAYRPSAAEFEKSVHKHTILRTYIEQNQQRQDQQQQQQQKEQDQQQQQPEPSSTKKPSRGWSLLTWRG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : . :: * . :: : ** *: *: * * :: : .. . : * * :.: . :* *:.* : :**. ::*:* . *. ** * *: . ** . ", "identical_positions": 24, "similar_positions": 36, "identity": "5.74%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110309-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63484-1", "uniprot_id": "AKT3_RAT", "id": "Q63484-1", "name": "RAC-gamma serine/threonine-protein kinase", "aln": "---------------------------------------------------------------------------------------------------------------------MSDVTIVKEDWVQ-----------KRGEYIKNWRPRYFLLKTDGSFIGYKEKPQD---VDLPYPLN--NFSVAKCQLMKTERPKPNTFIIRCLQWTTVIER---------------------------------------------------------------TFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCSPTSQIDN-----IGEEEMDASTTHH---------------------------------------------------------------KRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR---HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR-TLSSDAKSLLSGLLIKDPNKRLGGGPDDPKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITITPPEK--------------------DDDDGMDCMDNERRPHFPQFSYSASGRE-----------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUA6-1", "uniprot_id": "AKT3_MOUSE", "id": "Q9WUA6-1", "name": "RAC-gamma serine/threonine-protein kinase", "aln": "---------------------------------------------------------------------------------------------------------------------MSDVTIVKEGWVQ-----------KRGEYIKNWRPRYFLLKTDGSFIGYKEKPQD---VDLPYPLN--NFSVAKCQLMKTERPKPNTFIIRCLQWTTVIER---------------------------------------------------------------TFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCSPTSQIDN-----IGEEEMDASTTHH---------------------------------------------------------------KRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR---HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR-TLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITITPPEK--------------------YDDDGMDGMDNERRPHFPQFSYSASGRE-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y243-1", "uniprot_id": "AKT3_HUMAN", "id": "Q9Y243-1", "name": "RAC-gamma serine/threonine-protein kinase", "aln": "---------------------------------------------------------------------------------------------------------------------MSDVTIVKEGWVQ-----------KRGEYIKNWRPRYFLLKTDGSFIGYKEKPQD---VDLPYPLN--NFSVAKCQLMKTERPKPNTFIIRCLQWTTVIER---------------------------------------------------------------TFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCSPTSQIDN-----IGEEEMDASTTHH---------------------------------------------------------------KRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR---HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPR-TLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTITITPPEK--------------------YDEDGMDCMDNERRPHFPQFSYSASGRE-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXT6-1", "uniprot_id": "E7EXT6_DANRE", "id": "E7EXT6-1", "name": "non-specific serine/threonine protein kinase", "aln": "---------------------------------------------------------------------------------------------------------------------MNDLNVVKEGWVQ-----------KRGEYIKNWRPRYFLLKTDGSFIGYKEKPQD---ADLAYPLN--NFSVAKCQLMKTERPKPNTFIIRCLQWTTVIER---------------------------------------------------------------TFHVDTPEERDEWVEAIQMVADKLAKQEEEGILCSPISQIEN-----VNEEEMDTSTSHH---------------------------------------------------------------KRKTMNDFDYLKLLGKGTFGKVILVREKASGTYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR---HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHSAKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDND-YGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIKFPR-TLSADAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFTALDWQDVYDKKLVPPFMPQVSSETDTRYFDEEFTAQTITITPPEK--------------------YDEDGMDAADSERRPHFPQFSYSASGRE-----------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8INB9-1", "uniprot_id": "AKT1_DROME", "id": "Q8INB9-1", "name": "RAC serine/threonine-protein kinase", "aln": "-MNYLPFVLQRRSTVVASAPAP--GSASRIPESPTTTGSNIINIIYSQSTHPNSSPTSGSAEKFSWQQSWPSRTSAAPTHDSGTMSINTT-------------FDLSSPSVTSGHALTEQTQVVKEGWLM-----------KRGEHIKNWRQRYFVLHSDGRLMGYRSKPADSASTPSDFLLN--NFTVRGCQIMTVDRPKPFTFIIRGLQWTTVIER---------------------------------------------------------------TFAVESELERQQWTEAIRNVSSRLIDVGEVAMTPSEQTDMTDVDMATIAEDELSEQFSVQGTTC------------------------------------------------------NSSGVKKVTLENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTN---HPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHSQGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDND-YGQAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPR-NITDEAKNLLAGLLAKDPKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDKEFTGESVELTPPDP--------------------TGPLGS----IAEEPLFPQFSYQGDMASTLGTSSHISTSTSLASMQ-----------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P11792-1", "uniprot_id": "SCH9_YEAST", "id": "P11792-1", "name": "Serine/threonine-protein kinase SCH9", "aln": "MMNFFTSKSSNQDTGFSSQHQHPNGQNNGNNNSSTAGNDNGYPCKLVSSGPCASSNNGALFTNFTLQTATPTTAISQDLYAMGTTGITSENALFQMKSMNNGISSVNNNNSNTPTIITTSQEETNAGNVHGDTGGNSLQNSEDDNFSSSSTTKCLLSSTSSLSINQREAAAAAYGPDTDIPRGKLEVTIIEARDLVTRSKDSQPYVVCTFESSEFISNGPESLGAINNNNNNNNNNQHNQNQHINNNNENTNPDAASQHHNNNSGWNGSQLPSIKEHLKKKPLYTHRSSSQLDQLNSCSSVTDPSKRSSNSSSGSSNGPKNDSSHPIWHHKTTFDVLGSHSELDISVYDAAHDHMFLGQVRLYPMIHNLAHASQHQWHSLKPRVIDEVVSGDILIKWTYKQTKKRHYGPQDFEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKSSPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHDNDIVYRDLKPENILLDANGNIALCDFGLSKADLKDR--TNTFCGTTEYLAPELLLDETGYTKMVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRNPKHRLG-AIDDGRELRAHPFFADIDWEALKQKKIPPPFKPHLVSETDTSNFDPEFTTASTSYMNKHQPMMTATPLSPAMQAKFAGFTFVDESAIDEHVNNNRKFLQNSYFMEPGSFIPGNPNLPPDEDVIDDDGDEDINDGFNQEKNMNNSHSQMDFDGDQHMDDEFVSGRFEI", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: . : : .:. .. : :: :.. :. :. . . :.:: .: : . .. .::: :: : .*.. .: .. .: : :: *:. : * .. . : :. : :: ::*: *::*******:* ::* : **:*:*.*:**: *:*:***: * .:* .* **: .**:**** * :* :*:.*****:**.:* *:***::** **:: ** :**. *:***** **::** :*:* : ****.* .:. :*****.******:* *: * : **:*. **:::** ** **: .::: :: * . .:**** :: :.:.:: *** ::*::*** . ** :*: *.**: ::* : **: *** *:: *:*** ** *** : . . .. * * ** . . ", "identical_positions": 140, "similar_positions": 162, "identity": "16.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110310-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AY14-1", "uniprot_id": "F161A_RAT", "id": "Q6AY14-1", "name": "Protein FAM161A", "aln": "--------------------------------------------------------MWQIRASAGCHSSPG---KDKEVTLENTMNFSDIYHSDEEYFRKLKDLRAAHAEAMVKLEKMYQDKLTMKDIQAALVGD----DSSSSASEKSCSHPALSATSLSEP----DLDRSSSLSTT-TDE-LPDLEKKTPGEIGTRSYAKELINNMWNDFSVEDYTQY-DSDLQTAKK---------NRKKPKAWTPRITVPVPFEMTVREQKRREKASDAQ---ETREKMLKRNEDDA-ECKKKFRANPVPSRLLLPLYEDLVKQNEERRKKTRERSKAALLASQKPFKFIAREEQKQAIREKKLRELCRAKKKPKQ------FKARPVPRFIYRPPANVKPKREELYGDSRTQPKARDVLQSS-PWPSHSTY-----RAFRDPRSPAMPRGKHRHRRLSPSDQGL-EKWKEPFSEQSFRNCPVLCDQCCLYESLCDSNKRQKILADIRMGEEILKETRRPNP-----SPRHKSPRRSAHASARPCEYSPPMPTAS-------------------------------------------------------SRGREQAIRRSEKARMKELARIGGAR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8QZV6-1", "uniprot_id": "F161A_MOUSE", "id": "Q8QZV6-1", "name": "Protein FAM161A", "aln": "------------------------------------------------------------------------------------MNFSDIYHSDEEYFRKLKDLKAVHEETMSKLEKMYQDKLNIKDIQAGFIRDGISDSSSSSASEKSCSHPALSVTSLSEP----DLDGSSSLSTT-TDEGLPDLEEKTPGESSAMVHAQELINNMWNDFSVEDYIQY-DSDSRTAKK---------KRKKAKSLTPKITVPVPFEMTVREQNRREKALSARS--DLETKLLKRDEDDA-ECKKKFRANPVPSCVLLPLYEDLVKQSEERRKKARERNRAALLASLKPFKFIAREEQKQAVREKKLRDLFRAKRKTNQ------FKAKPVPRFIYRPAASDKPKEEELYGDSRMLPKVRDLLQNS-PWPSRSAC-----RRFRDPRSPAKPRGKHRRRCLR-RDGDL-EKWKEPFSEYSFLKCPMLCEECCLHESPCDSDKRQKLLADIRADEEILRETRRPGR-----SPRRKSPGRSSNPKPRPHECSPPMPTAS-------------------------------------------------------SRGREQAIRRSEKARMREYWQELEEQEEKLQKRPMLFERVTQVVFIG---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3B820-1", "uniprot_id": "F161A_HUMAN", "id": "Q3B820-1", "name": "Protein FAM161A", "aln": "MATSHRVAKLVASSLQTPVNPITGARVAQYEREDPLKALAAAEA--ILEDEEEEKVAQPAGASADLNTSFSGVDEHAPISYEDFVNFPDIHHSNEEYFKKVEELKAAHIETMAKLEKMYQDKLHLKEVQPVVIREDSLSDSSRSVSEKNSYHPVSLMTSFSEP----DLGQSSSLYVSSSEEELPNLEKEYPRKNRMMTYAKELINNMWTDFCVEDYIRCKDTGFHAAEK---------RRKKRKEWVPTITVPEPFQMMIREQKKKEESMKSKSDIEMVHKALKKQEEDP-EYKKKFRANPVPASVFLPLYHDLVKQKEERRRSLKEKSKEALLASQKPFKFIAREEQKRAAREKQLRDFLKYKKKTNR------FKARPIPRSTYGSTTNDKLKEEELYRNLRTQLRAQEHLQNSSPLPCRSACGC---RNPRCPEQAVKLKCKHKVRCPTPDFEDLPERYQKHLSEHKSPKLLTVCKPFDLHASPHASIKREKILADIEADEENLKETRWPYL-----SPRRKSPVRCAGVNPVPCNCNPPVPTVS-------------------------------------------------------SRGREQAVRKSEKERMREYQRELEEREEKLKKRPLLFERVAQKNARMAAEKHYSNTLKALGISDEFVSKKGQSGKV------------------LEYFNNQETKSVTEDKESFNEEEKIEERENGEENYFIDTNSQDSYKEKDEANEESEEEKSVEESH-----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9W4-1", "uniprot_id": "E7F9W4_DANRE", "id": "E7F9W4-1", "name": "Protein FAM161A", "aln": "MKKSHRTNVLVTSCLKTPVDPQTKVPLAQYERERTLPRAAAMTDNRHYEKEMEYDSGSDLVADDPPAKDNNALLIKDYRVTGDRIDLREFYFSNQEYYRKLEQLKTAHLQTMAELELMYRKKLDLKGATAVDNTERANLSPQGSPVITSGLKKAQSALELRRTSDPSDLSDEEGQGDRNTEKGLLISPKEHIKNMWQDFSVNKLSPPHRHPMSSSVHSLPADCQGISKPKERIRSQRAKKHKHHEDWHPRVTVPKPFQMTVREAEWRKKGVKSRSEIEQENADLRRQLEELSECQKKFRASPIPAHVRLPLYEDLQERNEERRRLHLEFEQQRLHISQKPFRFLERERLKKEQKDAKLREQTLQRNKEEEERRKCPFKAKPVPKAVKEATLGERQKEEELYRAIKMQMRAREMLHTASMPPSMLARQLSEKQTQKIIVKDAEETHQPKINAEVPDFDASYRRFRKQLAKRKEVMPVTSCEPFQLRTANITS-HKERIMAEIQAEIQSPKPSRWPFVNTPVLSPRTPSSSLCSSLSGSQECLSAKITDAAKKRQEAVRKVLEHRKKAEEEEEKWREKQKQREKRLQKLVTKRAQAIDPHVTLAQTSPNKLKEFRKQDLQRQKEYQDEMREIQKRVKGRPLLLEQVAQMNAKRAAEKLYSSTLHGCGLSESFISSKAPKGLENRLTPSPAHSDSMSPPTYRNRLEDDEDLPDMQDSLLDDYPDDYEEYDHDMETELVDGDEERKHSEHHDYGDEEKDDDDDDDDDEMQFDDDDCQGDDDIIRRHSQSSKGSDRSDHSNRSRTGSVN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN94-1", "uniprot_id": "Q9VN94_DROME", "id": "Q9VN94-1", "name": "", "aln": "-----MSSHYLNSCVKVPIDPCNNCPAPVYNRPK-------------------LSSLGGKKPTDQAHISQPEAETPAWSSQMGVRSLAKFYDS-IPDYRDVKHLHRVEFYSTLESLRSTSRELRSQAATAPTVERSASVSSCSVGHGKSKKRPSKGKKIKKRP---------------LVLDPVPPPAILVIPGQQDRCATRPVVHTPNSSCLSDEYDQCLRDLS--------------RLKSFKEDFAVEVADFKRSLKSFEAEFRRPKSTSSNGTQTQTNKQSQTQNRCQKTANPGQHTAERAKCRREMLRRCFSVNDLQGIALEAHSKPSKLAQPARSNYFPLSKQEEIPKIQIQSPTTSSKRSSSAS---SAARGRGRRGRVRKPKPGSSVKDEKPLPPLSIYELPEEPVQRRTPSVSPLHPVS--RPNLAATLRAEVSRKKVKELKNNCTYHDPRPQFDWEVRKTPAWKSLSLNESHKALLSIRLATRKAEQAFQERQYELHMEMMR---------QRVKSAPLLLEGPTFWGPEVGKLTHTCR-------------------------------------------------------TEELRHSCEGSRQRRKKKSEFPVPDADTKLQQLRKVYG--SEKSCSRQSQRSKRSERRPQGLTTETPSHDS-----------------------------GDDLCSADRAFL----------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: .:: * ::.::.*: .. : : :* : . .. .. : .. . : .. : . : . * : . .. .: * : :. : : : : : : : .. : : . . .: : .: . .:: .. :. : :.. . :.: . . * *: .: :: . : : :: . : . : : :: . : . . * . :. . . : : . . * :: ", "identical_positions": 9, "similar_positions": 111, "identity": "1.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110310-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZXY2-1", "uniprot_id": "D3ZXY2_RAT", "id": "D3ZXY2-1", "name": "PDZ domain-containing protein 8", "aln": "-----MGLLLMILASAVLGSFLTLLTQFLLLYRRQPEPRADEAARAGDGFRYLKPVPGLPLREYLYGGG--------------AEEPAAGSSEA------GASTTPTPDSPAPPTL---------ETCYFLNATILFLFRELRDTALARRWVTKKIKVEFEELLQTKTAGRLLEGLSLRDVFLGDTVPYIKTIRLVRPVVASGTGEPDEPDGDALPATCPEELAFEAEVEYNGGFHLAIDVDLVFGKSAYLFVKLSRVVGRLRFVLTRVPFTHWFFSFVEDPLIDFEVRSQFEGRPMP-QLTSIIVNQLKKIIKRKHTLPSYKIRFKPFFPYQALQGFEEDEDL-IHIQQWALTEGRLKVTLLECSRLLIFGSYEREANVHCTLELSSGVWEEK-QRSSIKTVELIKGNLQSVGLTLRLVQSTDGYAGHVIIETVAPNSPAAIADLQRGDRLIAIGGVKITSTLQVLKLIKQAGDRVLVYYQRPVGQ---SNQGAMLQDSLGQLEEN-FLSSSCQPGYEEEAAGLPVD--SETRDLDSEFEDLAGDVR-----VQTELKEETQP-LSHSPKRTPTTLSIKPLGAISPVLNRKLISGIHPPPQKLPSKEGNKPSTLKTSEATEAAQ-VSKP-QVPTFKPPVPPRPQGRVPLPPTDTSAQAD---PETTEKPEKVLLPPPPADKPAEKQVKSVDHGEDVAAGKQ---------PPAKQEVVKDAPSESSAPTKDPSDDHQMWESSEVLYRNKVGKWSRARASCVFDIEACHRYLNIALWCRDPFKLGGLICLGHASLKLEEVALGCLATSNMEYLSKFRLEPPAPKAMVTRTALRNLSMQKGFNDKFCFGDITIHFKYLKEGEPDHQIVPSVEKERELH----------VVEE-----------VSTLPKEDHFVGQMSLSENKHSFQDTQFQNPTWCDYCKKKVWTKAASQCMFCAYVCHKKCQEKCLAETPLCGATERRVDRTLKSLRLEGQDPLLGLPPRVEMEANKSVN-KTTGLTRHIINTSSRLLNLRQVSKTRLAEP----GTDLVEPSPKHTPNTSDNEGSDTEVCGPNSPSKR-GNSAGIKLTRKEGGLDDSVFIAVKEIGRDLYRGLPTEERIQKLEFMLDKLQNEIDQELEHNNSLVREEKETNDTRKKSVLSASLAKSGERLQALTLLMIHYKAGIEDIETLENLSLDQHSKKMNKYTEDTEEDL------DSEISQLIDSQPFSNISDDLFGPSESV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B9EJ80-1", "uniprot_id": "PDZD8_MOUSE", "id": "B9EJ80-1", "name": "PDZ domain-containing protein 8", "aln": "-----MGLLLLILASAVLGSFLTLLAQFLLLYRRQPEPRADEAARAGDGFRYLKPVPGLPLREYLYGGG--------------AEELAACSSEA------GASSTPTPDSPAPPTL---------ETCYFLNATILFLFRELRDTALARRWVTKKIKVEFEELLQTKTAGRLLEGLSLRDVFLGDTVPFIKTIRLVRPVVASGTGEPDDPDGDALPATCPEELAFEAEVEYNGGFHLAIDVDLVFGKSAYLFVKLSRVVGRLRFVLTRVPFTHWFFSFVEDPLIDFEVRSQFEGRPMP-QLTSIIVNQLKKIIKRKHTLPSYKIRFKPFFPYQALQGFEEDEEL-IHIQQWALTEGRLKVTLLECSRLFIFGSYDRETNVHCTLELSSGVWEEK-QRSSIKTVELIKGNLQSVGLTLRLVQSTDGYAGHVIIETVAPNSPAAMADLQRGDRLIAIGGVKITSTLQVLKLIKQAGDRVLVYYQRPAGQ---SSQ-----DSLGQLEES-FLSSSCQAAYEEDAAGLSAD--TENRDLDSEFEDLASDVR-----VQTELKEETQP-LSHSPKRTPTTLSIKPLGAISPVLNRKLISGIHPPPQKLPSKEGNKPSTLKTSETTEAAQ-VSKP-QGPTFKPPVPPRPQGRVPLPPTDTSAQAD---PEAPEKPDKVLLPPPPADKPAEKQVKSVDQGEDVAAGKQ---------SSAKQEGVKDLPSESSAPTKDSSDDPQMWESSEVLYRNKVGKWSRTRASCVFDIEACHRYLNIALWCRDPFKLGGLICLGHVSLKLEEVALGCLATSNMEYLTKFRLEPPTPKAMVTRTALRNLSMQKGFNDKFCFGDITIHFKYLKEGEPDHHIVPNVEKEKELH----------LVEE-----------VSTLPKEEHFVGQMSLSENKHSFQDTQFQNPTWCDYCKKKVWTKAASQCMFCAYVCHKKCQEKCLAETPLCGATERRIDRTLKNLRLEGQDPLLGLPPRVEIEANKSVN-KTTGLTRHIINTSSRLLNLRQVSKTRLSEP----GTDLVEPSPKHTPNTSDNEGSDTEVCGSNSPSKR-GNSAGIKLMRKEGGLDDSVFIAVKEIGRDLYRGLPTEERIQKLEFMLDKLQNEIDQELEHNNSLVREEKETNDTRKKSVLSAALAKSGERLQALTLLMIHYRAGIEDIETLENLSLDQHSKKMNKYADDTEEDL------DSEISQLIDSQPFSNISDDLFGPSESV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NEN9-1", "uniprot_id": "PDZD8_HUMAN", "id": "Q8NEN9-1", "name": "PDZ domain-containing protein 8", "aln": "-----MGLLLMILASAVLGSFLTLLAQFFLLYRRQPEPPADEAARAGEGFRYIKPVPGLLLREYLYGGGR-------------DEEPSGAAPEG------GATPTAAPETPAPPTR---------ETCYFLNATILFLFRELRDTALTRRWVTKKIKVEFEELLQTKTAGRLLEGLSLRDVFLGETVPFIKTIRLVRPVVPSATGEPDGPEGEALPAACPEELAFEAEVEYNGGFHLAIDVDLVFGKSAYLFVKLSRVVGRLRLVFTRVPFTHWFFSFVEDPLIDFEVRSQFEGRPMP-QLTSIIVNQLKKIIKRKHTLPNYKIRFKPFFPYQTLQGFEEDEEH-IHIQQWALTEGRLKVTLLECSRLLIFGSYDREANVHCTLELSSSVWEEK-QRSSIKTVELIKGNLQSVGLTLRLVQSTDGYAGHVIIETVAPNSPAAIADLQRGDRLIAIGGVKITSTLQVLKLIKQAGDRVLVYYERPVGQ---SNQGAVLQDNFGQLEEN-FLSSSCQSGYEEEAAGLTVD--TESRELDSEFEDLASDVR-----AQNEFKDEAQS-LSHSPKRVPTTLSIKPLGAISPVLNRKLAVGSHPLPPKIQSKDGNKPPPLKTSEITDPAQ-VSKPTQGSAFKPPVPPRPQAKVPLPSADAPNQAE---PDVLVEKPEKVVPPPLVDKSAEKQAKNVDAIDDAAAPKQ---------FLAKQEVAKDVTSETSCPTKDSSDDRQTWESSEILYRNKLGKWTRTRASCLFDIEACHRYLNIALWCRDPFKLGGLICLGHVSLKLEDVALGCLATSNTEYLSKLRLEAPSPKAIVTRTALRNLSMQKGFNDKFCYGDITIHFKYLKEGESDHHVVTNVEKEKEPH----------LVEE-----------VSVLPKEEQFVGQMGLTENKHSFQDTQFQNPTWCDYCKKKVWTKAASQCMFCAYVCHKKCQEKCLAETSVCGATDRRIDRTLKNLRLEGQETLLGLPPRVDAEASKSVN-KTTGLTRHIINTSSRLLNLRQVSKTRLSEP----GTDLVEPSPKHTPNTSDNEGSDTEVCGPNSPSKR-GNSTGIKLVRKEGGLDDSVFIAVKEIGRDLYRGLPTEERIQKLEFMLDKLQNEIDQELEHNNSLVREEKETTDTRKKSLLSAALAKSGERLQALTLLMIHYRAGIEDIETLESLSLDQHSKKISKYTDDTEEDL------DNEISQLIDSQPFSSISDDLFGPSESV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5N0-1", "uniprot_id": "A0ACD6B5N0_DANRE", "id": "A0ACD6B5N0-1", "name": "", "aln": "-------MIYLILLSAFSGAVVTLLLQLLLLYRRSPEP----VART---VQYVKVVPDPALKDYFSSQQADSAPQQPDSPSPVSKQPEAASPKQQETPVPGSSPKQQPSSPPPPSLSDPQHSSKAETCDFLNAIILFLFRELRDTPVVRHWITKKIKVEFEELLQTKTAGRLLEGLSLRDVSLGNSVPVFKTARLMKPVAVNED-------------NMPEELNFEVDLEYNGGFHLAIDVDLVFGKSAYLFVKMTRVAGRLKLQFTRMPFTHWSFSFLEDPLIDFEVKSQFEGRPLP-QLTSIIVNQLKRVIKRKHTLPNYKIRYKPFFPFQVQPPLMSSCDLDISIRDTLLVEGRLRVTLVECSRLFILGSYERETYVHCTFELSSDEWREK-TRSSIKETEVIKGPSGSVGMTFRHVPASDGDTVHVSIETVTPNSPAALADLQRGDRLIAIGGVKVTSSVQVPKLLKQAGERVIVLYERPVRHHVPTGGLGMLQETLGPMEEPSYLPQ--PGGYEEDPAPITTMDISENKDNDSEFEELNVESKTAAAPVTIDTKEDFLLSVNQSPKKTVANL-AKPLGSISPILNRRLN---LQSPLKTQPKESPKPPTLKNAEPSEQPQRPTVPPPPPPARPPVPPRPHIKVTSASSEAQSLVEGNEPTVEKSPEKTQPNTGNGEKPVEKIPVKPPEPKPVSKHPEPTEDILNIPATNKQDSAKDKISESSSNTRDSVDEQGLWESSETMYRNRTARWN--KASVIFEVESNHKFLNVALWCKNPFKLGSLLCLGHVSLRLEHLALECISTSSAEYQSTFRLCAPEPRASVSRTALRSLSTHKGFNEKLCYGDVTLNFTYLADGESDLSSG-LMERERKGS----------LQEEDLKDREKEREQVLMVTRDEPIYSGMQIGEMRHNFQDTQFQNPTYCEYCKKKVWTKAASQCMICSYVCHKKCQEKCLLEHPYCVAASDRRG--------------------ADPEAKSTINRATTGLTRHIINTSSRLLNLRQVPKARLAEQVADMGSGVVEPSPKHTPNTSDNESSDTETYTGASPSKQPAGSSGSKLVRKEGGLDDSVFIAVKEIGRDLYRGLPTDERSQKLELMLDKLQQEIDQELEHNNSLSTEERDTIDSRRKTLITAALAKSGERLQALTLLMIHYRAGIEDLESVESTSPSEQHGFPKAKSEGLEEALMGTEVYDSDMCSPVDVQMLDEITEEQICVEALP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VYR9-1", "uniprot_id": "PDZD8_DROME", "id": "Q9VYR9-1", "name": "PDZ domain-containing protein 8", "aln": "MEIPISNILLLCLIFLLIGGVVMILLQYLIFIKFSNLPDESEEQKQAN-AKYTLPLNIKQTARNLKRLS---------------NSGLGGGAGN------GCENHQESLRRASALVS-------------LNFVMQFLFHEFKNSNRVRKWFYRKLSIELDELISKTTTGKLLDKLTIKELELGDQFPDVKSLSVHNVELDKDE-------------QRIENLDLLLDINYVGNFTTSIDADMVLGKKGSITLRVKQLSGMARLQFTRKPYTHWSISFLGDPELILDIESKYQGRQMQSNITNLISNQIRKAVRRKHTLPNYKLRYKPFFHWTAEEDASDCDIQ---------PNGLLTVKLAELSRLMG---YPGASETYCTITLAPVPFIEASQRDSRNVLISLDVFIHKAKNQQIGIVFKQSGSQVVRIESVLPNTPACKSNLLAGDVLVAIEGRPVTTIQQIAKVVKTLQATVFSLRIERIIP-----------------------------------GIIRNDAILEDFEKYEDIGDLPSSYP--------------------------------------------------------------CQPKLETDEAATADP--------------TPKHLVVKPSLSGTPTNSPKK---SNLIAKAIKKTMSRESGDKDRDKDKDK-DKDKDKDKDKD-------------KDKDKDKDKDKG---KEEVEEPVNYFYQHSTIDCPFSPLIHMEDVCSFQLDNSSRFLNVCVFGKS---AGESVLLGYNNVQIGQILVECSETSLNQCLKQISLNPASLQAVKT----HPLSNQSGFNPNLCFGDILFGFSWMGNPNLTVGDVPIKSTSKSQSPARNPLAGDRVASEDQSQFLKLTSSMADSSTSGESSSGTTAAPRAHDFVRTHFHRATQCDFCGKKIWLKDAMQCQECSMCCHKKCIVKCQMAT-VCGPVDCTGSIPATSSTPSMASRPEFTITQADNPQIVDSSTGATPFDETSAASGGDQGQIQSPTASGLDVHR-SSLTGMLAQGIKRQASNLDIPGIVSSLTGSGQQVNS--KSLPPSPQHTPSRKSSIVEEATPALQQNPFESVTQHLEALPLDCPELSFEQVIVITEPIIRHTRNEDLMNLAKSTSKLLYAALP-PDERVAKINELLTKLKVALDAETEGYTLMNDAEKATESSPWKSDRSDE------RVQALSIIMLYLCTGLQHAQGVVLQ--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : * . *..: :* * ::: : . * : :* : : :. . .. *. . ... ** : ***:*:::: .*:*. :*:.:*::**:...*:*:**: *::::: **: .* .*: : . . *:* : :::* *.* :**.*:*:**.. : :::.:: * :: :** *:*** :**: ** : :::.*:::** : ::*.:* **::: ::******.**:*:**** : . . :* * *.* * ***: * : .:**: *:. : * *.* : :. .. : .:. : * **:* **:**. ::* ** *:** * :*: *: *::* *: . . : * : .:: :* . . *:. * : .* : : . . : : . . . : :* :* . . : :: ** .:.. :: :: : .. . . *::: ::**:.:: :. * : **: .::: .: : * ** : . : * .. :* : : ** :.*** ::*:**: : *.:: : : . .:. : .* : . . . *.* *:*:..* *::* **:* * * ** *: ***** ** * ... . .: . :* : . :.. :::. . : * :.:: . *: ... * . :. . : * . :. . .. * *. : :: :..:. . . *: .::: * . *: . . ..:: *:*. ..**: :. *: : :..:: . . . . .. .. : . : : . ", "identical_positions": 173, "similar_positions": 336, "identity": "13.86%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110310-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q02952-1", "uniprot_id": "AKA12_HUMAN", "id": "Q02952-1", "name": "A-kinase anchor protein 12", "aln": "-------------------------------------------------------------------------MGAGSSTEQRSPEQPPEGSSTPAEPEPSGGGPSAEAAPDTTADPAIAASDPATKLL--------------------------QKNGQLSTINGVAEQDELSLQEGDLNGQKGALNGQGALNSQEEEEVIVTEVGQRDSEDVSKRDSDKEMATKSAVVHDITDDGQEETPEIIEQIP-----------------------SSESNLEELTQPTESQANDIG--------------------------------------------------FKKVFKFVGFKFTVKKDKTEKPDTVQLLTVKKDE-------------GEGAAG---AGDHKDPSLG-AGEAASKESEPKQ------------STEKPEETLKREQSHAEISPPAESGQ-AVEECKEEGEEKQEKEPSKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTSFRKPKEDEVEASEKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQEPAES-------------AHEPRLSAEYEKVELPSEEQVSGSQGPSEEKPAPLATEVFDEKIEVHQEEVVAEVHVSTVEERTEEQ-------KTEVEETAGSVPAEELVEMDAEPQE---AEPAKELVKLKETCVSGEDPTQGADLSPDEKVLSKPPEGVVSEVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGG--DEESGEHTQVPADSPDSQEEQKGESSASSPEEPEEITCLEKGL--------------------AEVQQDGEAEEGATSDGEKKREGVTPWASFKKMVTPKKRVRRPSESDKEDELDKVKSATLSSTESTASEMQEEMKGSVEEPKPEEPKRKVDTSVSWEALICVGSSKKRARRGSSSDEEGGPKAMGGDHQKADEAGKDKETGTDGILAGSQEHDPGQGSSSPEQAGSPTE-------------GEGVSTWESFKRLVTPRKKSKSKLEEKSEDSIAGSGVEHSTPDTEPGKEE-------------------------------------SWVSIKKFIPGRRKKRPDGKQEQAPVEDAGPTGANEDDSDVP------------------AVVPLSEYDAVEREKMEAQQAQKSAEQPEQKAATEVSKELSESQVHMMAAAVADGTRAATIIEERSPSWISASVTEPLEQVEAEAALLTEEVLEREVIAEEEPPTVTEPLPENREARGDTVVSEAELTP---------EAVTAAETAGPLGAEEGTEASAAEETTEMVSAVSQLTDSPDTTEEATPVQEVEGGVPDIEEQERRTQEVL-QAVAEKVKEESQLPGTGGPEDVLQPVQRAEAERPEEQAEASGLKKETDVVLKVDAQEAKTEPFTQGKVVGQTTPESFEKAPQVTESIESSELVTTCQAETLAGVKSQEMVMEQAIPPDSVE----TPTDSETDGSTPVADFDAPGTTQKDEIVEIHEENEVASGTQSGGTEAEAVPAQKERPPAPSSFVFQEETKEQSK------MEDTLEHTDKEVSVETVSILSKTEGTQ--EADQYADEKTKDVPFFEGLEGSIDTGITVSREKVTEVALKGEGTEEAECKKDDALELQSHAKSPPSPVERE-------------------MVVQVEREKTEAEPTHVNEEKLEHETAVTVSEEVSKQLLQTVNVPIIDGAKEVSSLEG--SPPPCLGQEEAVCTKIQVQSSEASFTLTAAAEEEKVLGETANILETGET--------------------------------LEPAGAHLVLEEKSSEKNEDFAAHPGEDAVPTGPDCQAKS----------------------------------------------------------------------TPVIVSATTKKGLSSDLEGEKTTSLKWKSDEVD---EQVACQEVK--VSVAIEDLE-PENGILELETKSSK--------------------------------LVQNIIQTAVDQFVRTEETATEMLTSELQT----------------------------------------------------------------QAHVIKADSQDAGQETEKEGEEPQASAQDETPITSAKEESESTAVGQAHSDISKDMSEASEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGAGTKSVPEDDGHALLAERIEKSLVEPKEDEKGD-----------------------------------------DVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKEDAQEVELQEGKVHSESDKAITPQAQEELQKQERESAKSELTES--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9WTQ5-1", "uniprot_id": "AKA12_MOUSE", "id": "Q9WTQ5-1", "name": "A-kinase anchor protein 12", "aln": "-------------------------------------------------------------------------MGAGSSTEQRSPEQPAES-DTPSELELSGHGPAAEAS-GAAGDP--ADADPATKLP--------------------------QKNGQLSAVNGVAEQEDVHVQEESQDGQ--------------EEEVTVEDVGQRESEDVKEKDRAKEMAASSTVVEDITKDEQEETPEIIEQIP-----------------------ASESNVEEMAQAAESQANDVG--------------------------------------------------FKKVFKFVGFKFTVKKDKNEKSDTVQLLTVKKDE-------------GEGAEASVGAGDHQEPGVETVGESASKESELKQ------------STEKQEGTLKQAQSSTEIPLQAESGQGTEEEAAKDGEENREKEPTKPLESPTSPVSNETTSSFKKFFTHGWAGWRKKTSFKKPKEDDLETSEKRKEQEAEKVDEEEGEKTEPA--------PAEEQEPAEG-------------TDQARLSADYEKVELPLEDQVGDLEALS-EKCAPLATEVFDEKTEAHQ-EVVAEVHVSTVEKMTKGQGGAEVEGDVVVEGSGESLPPEKLAETQEVPQE---AEPVEELMKTKEVCVSGGDHTQLTDLSPEEKMLPKHPEGIVSEVEMLSSQERIKVQGSPLKKLFSSSGLKKLSGKKQKGKRGGGGGDEEPGEYQHIQTESPESADEQKGESSASSPEEPEEIACLEKGP--------------------SEAPQEAEAEEGATSDGEKKREGITPWASFKKMVTPKKRVRRPSESDKEEELDKVKSATLSSTESTASGMQDEVRAVGEEQRSEEPKRRVDTSVSWEALICVGSSKKRARKASSSDDEGGPRTLGGDGHRAEEASKDKE--ADALPASTQEQDQAHGSSSPEPAGSPSE-------------GEGVSTWESFKRLVTPRKKSKSKLEERAED----SGAEQLASEIEPSREE-------------------------------------SWVSIKKFIPGRRKKRADGKQEQAAVEDSGPGEINEDDPDVP------------------AVVPLSEYDAVEREKLEAQRAQENVELPQLKGAVYVSEELSKTLVHTVSVAVIDGTRAVTSAEERSPSWISASMTEPLEHAEGVATPPVGEVTEKDITAEATP-ALAQTLPGGKDAHDDIVTSEVDFTS---------EAVTAAETTEALRAEELTEASGAEETTDMVSAVSQLSDSPDTTEEATPVQEVEGGMLDTEEQERQTQAVL-QAVADKVKEDSQVPAT-QTLQRAGPKALEKVEEVEEDSEVLATEKEKDVVPEGPVQEAETEHLAQGSETVQATPESLE-VPEVTEDVDR---ATTCQ------VIKHQQLMEQAVAPESSE----TLTDSETNGSTPLADSDTPNGTQQDETVDSQDSNAIAAVKQSQVTEEEAAAAQTEGPSTPSSFPAQEEHREKP-------GRDVLEPT-QALAAGAVPILAKAEVGQEGEAGQFDGEKVKDGQCVKELEVPVHTGPNS--QKTADLTRDSEVMEVARCQETESNEEQSIS-----PEKRE-------------------MGTDVEKEETETKTEQAS-EEHEQETAAPEHEGTHPKPVLTADMPHSERGKALGSLEG--SPS-LPDQDKADCIEVQVQSSDTPVTQTTEAVKK--VEETVATSEMDES--------------------------------LECAGAQSLPAEKLSETGGYGTLQHGEDTVPQGPESQAES----------------------------------------------------------------------IPIIVTPAPESILHSDLQREVSASQKQRSDEDN---KPDAGPDAAGKESAAREKILRAEPEILELESKSNK--------------------------------IVQSVIQTAVDQFAR-TETAPETHASDLQN----------------------------------------------------------------QVPVMQADSQGAQQMLDKDESDLQVSPQDGTLSAVAQEG-------LAVSDSSEGMSKASEMITTLAVESASVK---------------------------------ESVEKLPLQCK-DEKEH-----------------------------------------AADGPQHQSLAKAEADASGNLTKESPDTNGPKLTEEGDALKEEMN--KAQTEED---------DLQE-----PKGDLTES--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F983-1", "uniprot_id": "E7F983_DANRE", "id": "E7F983-1", "name": "", "aln": "MGAATSSARRDSRGEEDAAAEELTAAGSDAPEDGSAADDKLLQTNGLISNLNVKTKEPADELNCQFEERVLADVGSGFVTLKEDGTETLEDLQNLDPLQPNAKNESGEMVNAGVTLKEETEVDSQVNDINEVGFKRIFRFVGFKLTLKKDACEKTQANEQKETEENEQKEDNASEEAKDEDSDVAAIEITPDETHKSEESSDAAEPPSQQTDNETELDQDIKIVEFHVVDTPGKEMEKESSIEPEEPMSPIKQFFTQGIFASLRKKKKEEEIQKESKEEELKENEKTIAEEEAEKQDSKCMCLDIPYIISEDGKDSQEKGDDSLLPEGELQNSLEKDKVQGSPLKRLFRKFSSRRQREGKAAEKVAEVEEQVSEQPKPSSELGKAEEPLIGETVIEEPTVGEPKPADEQPVGDVGPQESKKKSDTTVSWEALICGGSAKKRARKTNEDEMSDKGQEHDKVTDSPLGSSIEGDYDHLTSSNEQTGSPAEGEVGSTWKTFKKMVTPKRKVRPGESSTPEQIPSDGEMSKDESFSKKKLIPGHKKRKSEAKQDQTSSDEVAKDHESDDETPAIIPLSEYEVIEPETLKEMNEQRVEITIEHEMPEIPSQALEKDTFKTVTKVSSNTAPAIIQSLSEDFEELTDFLSKHQQLSDIPEEGIEESIETPVSSAEWTTQDDTLAEDIVELTADAVTAPEPESILGDDTTEMVSALSQLTESPRSSGHVTPVSAEYDVQTSDAILHEAIQSICMTPSVQSITTKDESQKSLAVSFSPYIVQSSTPEETKVLVAHKKTEATAICIGLVSQEIESVEKHLPAPLVEAILEICDTVPTEVASDNFTDEHEVAGIGTDEVYEAEIKDVKTEFQERIVNEEESTSESERDIEQVIQLVTEPLVDESEETHIKDKKEESTTGIELRQDIDTMQSESGLDQVMLDITHGPELECPSYSTDEIAYNQLAAGEPTLDTISQVDEQETVDKILDITKAIDAPVEDTASAVECLEIKENVNIISPITDQIQVETIVLEDSLQIKDVPSIQADVKDADLSVDDSGDMSIKDIGEKMEASGDEKIAQQEIKEDHLEEETGDVVSSELVQNVKAENIAESIDDLLVKEQLPAEKASLTEPVLEKAKEAHKDVTDTDVDDKVVDNAHDRADRIFVKDELAPKNEQPLTDTDSNETENQDLSTHLNSMSESPGIVVGETEKGQTEDIIPVVSEFSKDVLEPTKTPTEPEVSCEAIPTSLGIPSAEVEVKSIPEEIVTFKTEECSQDIQQNEQLQTSENNKTSKVLEMVAITENTTKQLEQEKAIVAEPEAQVLTMSELPKATEQEGDSSEVTVVHGEANDSDQAQAVTLTDTIRTAVQDEIYKEAVASILKPERVDSRMTVTEENEAYADSMQKCEPLRQKTEMTLSKELQVDKTNNKDEILAVTEVIPKEQVPPLRSEVTAEMPDVTVSEVQTKVESELRAATLEVTEPKVEMPVITEVTVESAVVTEPEVERPIVTSVVAELEVETPVVTSTTKATDTHTSQIIDADTTELTTVIKEDVEEKPTVISVVVTPATPLDEATPVLTQSHESRVVDEVKDESVEPRAIETPKVEAVIVRSVLAPAVEIQNVIPVVKAPNLGSVTMTEGSSPVVEATVLETTAATAIKPDVVEIPVVQTPNIDSVIMLPAITSVPSKEVTLDLTSFAETPLDNVTEIPVVSLTSVKPTVAALMQTPDAEIQARIPMTVTEVACPVVVTTDVTPVAPGGIVIPAVETPHATSSTVVLKTPTQISVTVTEAEAPVTTSVAASAVIPVEETVRVKETSPPGVVSVTAAVETPATIPVVQTPAVKLSSLAMVETPVVTPVVLMPNQVSEKAKETALSAVISAVETAPVIPAEEYPVVKLTQVAVVEAQVVHPMAETPGQGLVRLTETSLPAIVSDVTAAVETPAIISVVETPVVMTTPVTNFELPVVSTAVEIPGLVSEIVKETASPTVVSAEETLPVIPVVQTPTVKSTEVAVVEPPVVTLDQVSSLVSETSPPVDVSTVEAPAVIPVVETQVVKSTPVAVIEIPVVTPMVQTPGEVSVIVKETAPPADDLSVETSPVMPIIENLVVKSTPVSVLDAPAVTPVVQTPGQGSASVIETSPLPIVSGATALVEAPIMIPVVETPVVMDEMPIMTKVIQTPGQDLMMVKETTPQVVSAVETPLVIPVVETPVVTSTQLKAVEATGVLPAVQALAQDSVRETETLPQAIVSGVTAAVEAPTMIPVVEIPVAMVEIPVVPPVVQGPDQGSVRVSETSPPSVVSGVTAPVETPAMIPAVETLVVMSTPVAAVETPVVTSVVQTASQVSGIVKEIVPPADASAVTSRDETPAVNSTPVAVVDPLVLTPVVQISEQVSMKVTEALPPAEVETVVLTAVVETAVVNPPPTAVTETPVLTPVVQISEQVSLTVKETSPPAVPETSVLTLIVETPVVIPAPAAVTETPVLTPVVQISEQVLLRAEETSLPAVAETSVSTPLVETSVAKSAPSAVTEIPVLTPVVQISEQVSLTVKETSPPAVPETSVLTQVVETPVVIPAPAAVTETPVLTPVVQISEQVSLRAEETSLPAVAETSVSTPLVETSVAKSAPSAVTETPVLTPVVQISEQVSLRAEETSLPAVAETSVSTPLVETLVAKPAPSSVTVTPVLTPVVQISEQTSVRVTETLPPAVAETAVLTPVVETPVAKPAAVTETPVLTPMVQTPRQVIVTVTETALPVVASAVNAAAEKPFVVPVESSVLKPTLMTTPIMTSVVERSVLSLVLETTAPTTIALTERPVMIPMVQTPALVSVIVKETAPPVVLPPVTTTAKIPVKSPAVETQAVKPTSAATETPIPVVPISESPVVTPVGEQVAETLTTPATPSVITPTIETVMESPAEVSEEKAKQQTEVAEALTLAPVVEAPATPQPVVTPDVKEAIVQVVAEDKKEANTEPYVVFEDAVQQQEVNTSIQENPKGPMPHKAVVPSTEPQPEMEEDVWEDAVDNIGDSHCQLTHTEGESQDTAAKEASEAVI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:* * :.. :. *. .. : .. . :.* . : *. .: * * * .: :. :::: : . :.: **. . : .::::: .: * ::. .* .. :*.: * * :. .**: **: : :: *:: . :*::*: .. : : . ** *: . :: : ** . .*: : .. .*: ..:**: *. .: * . .. :. :: :. : . :*: .: ....: **:. ..* .:***:.* ::* : .: * *:... .: : : .: *:* *. :*. : :. . : ::**:. *.:: . : ** : :. ...: : ::* . . .: :: * . * .:.. : . : * ... : : .: * * *: .. .: . .: . :.. . * : ..::.: :..::.:: *.:. * . . : . .::. :: . .:** .:** :: : . * :* : * :.*:: :. ::. ** * *: :: *... :..:*.* :.* * : : . : ::.:. * . ..: .. *:.: . : * : . .::* . : . . ..::*. . . .* * : :*:: .* ::. * : : * . :. . *.. :* . : :*: :*..: . .: *:* . . : ** * **:: *: * *: : . :. . . . ..: :: : :: * .... * . * : . : : .* . *: . : * ..: : . * . . :* :*:.* : * .* .:*: * :. *:.* ::..* :: .* .: :. .: * :* :. : : * .::. .: . . : * .:: :. ::: ::: . : :.. . : . :.. . .*. . : * .. : . .:. . * * . :* : .**:. : : . : : . ::: :. * :. : *.:* . :.: : :* . . *: .. . *. : . * . . :..: : . : * . : : . . * :. : .. : * : :. : : . . . * . : * * . : ::* :.. . . .: * .:::..* :. * : **. * . . . . : :: **. : .:* .* *:. *:: :.. * *:: * ::. ::* . .. * . : .* :::. :* ::**. : . ***. .::. :. *: : : :. .: : . . * * : * :. .. *:. : . :* : : . .: * . . : ::.** :.: * ::.. ... :: : . ::. .*: ", "identical_positions": 184, "similar_positions": 631, "identity": "6.09%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110310-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8J8Y7C5-1", "uniprot_id": "A0A8J8Y7C5_RAT", "id": "A0A8J8Y7C5-1", "name": "", "aln": "MLPAR-VRLLTPHLLLLLVQLSPAGGHRTTGPRFLISDRDPPCNPHCPRTQPKPICASDGRSYESMCEYQRAKCRDPALAVVHRGRCK---------------------------DAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPIS---------------------------------------GSSVQNKTPVCSG---------------------------TGGR------------YDGSKPTPTMETQPVF------------------------------------------------------------------------------------------------------------------------DGDEITAPTLWIKHLVIKDSKLNNTNVRNSEKVHSCDQERQSALEEARQNPREGIVIPECAPGGLYKPVQCHQSTG--YCWCVLVDTGRPLPGTSTRYVMPSCESDARAKSVEVDDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLEERVAHWYFSQLDSNSSDDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKAISLPELKGCLGVS-KEGESELHVIP--DGSQTGTLSLGCSNCRCQEAK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BLY1-1", "uniprot_id": "SMOC1_MOUSE", "id": "Q8BLY1-1", "name": "SPARC-related modular calcium-binding protein 1", "aln": "MLPAR-VRLLTPHLLLVLVQLSPAGGHRTTGPRFLISDRDPPCNPHCPRTQPKPICASDGRSYESMCEYQRAKCRDPALAVVHRGRCK---------------------------DAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPIS---------------------------------------GSSVQNKTPVCSGPV-----------------TDKPLSQGNSGRKVSFRFFLTLNSDDGSKPTPTMETQPVF------------------------------------------------------------------------------------------------------------------------DGDEITAPTLWIKHLVIKDSKLNNTNVRNSEKVHSCDQERQSALEEARQNPREGIVIPECAPGGLYKPVQCHQSTG--YCWCVLVDTGRPLPGTSTRYVMPSCESDARAKSVEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLEERVAHWYFSQLDSNSSDDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELKGCLGVS-KEGGS-LGSFP--QGKRAGTNPFIGRLV-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4F8-1", "uniprot_id": "SMOC1_HUMAN", "id": "Q9H4F8-1", "name": "SPARC-related modular calcium-binding protein 1", "aln": "MLPARCARLLTPHLLLVLVQLSPARGHRTTGPRFLISDRDPQCNLHCSRTQPKPICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCK---------------------------DAGQSKCRLERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPIS---------------------------------------GSSVQNKTPVCSGSV-----------------TDKPLSQGNSGRK-----------DDGSKPTPTMETQPVF------------------------------------------------------------------------------------------------------------------------DGDEITAPTLWIKHLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQCHQSTG--YCWCVLVDTGRPLPGTSTRYVMPSCESDARAKTTEADDPFKDRELPGCPEGKKMEFITSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLEERVVHWYFSQLDSNSSNDINKREMKPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELKGCLGVS-KEGRLV-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PKH8-1", "uniprot_id": "A0A8M9PKH8_DANRE", "id": "A0A8M9PKH8-1", "name": "", "aln": "MNCHN--LALCVFMYLMVMRLPAASTQKSTGPRWLIGDRESPCSTSCSRSHGKPVCGSDGRSYDTNCDLERAKCRDRTLTLAHRGRCKGKNWVRIDQPLLVPTLVSEVKELTGMKEAGQTKCRTERIQALEQAKKPQESIFIPECNDDGTFAQVQCHTLTGYCWCVTTDGKPVS---------------------------------------GSSVQNKTPVCSGNFREFMGTHAGTSGLSGSVTDKPPGPPSSGKKVSFRFFLTLNPDDGSKPTPTMEPHVVP------------------------------------------------------------------------------------------------------------------------EGEEITAPTLWIKQLVYKENKQNSSNSRKSEKVPSCDQERQTAQDEARQNPREAIFIPDCGLQGLYKPVQCHQSTG--YCWCVLVDTGRPIPGTSARYKKPECDSAARSRDTEMEDPFRDRDLTGCPEGKKVEFITSLLDALTTDMVQAINSPTPSGGGRFVEPDPSHTLEERVVHWYFAQLDNNGSHDINKKEMKPFKRYVKKKAKPKRCARKFTDYCDLNKDKTISLQELKGCLGVN-KEGSTTSSSQGTRQGTNLFSKVFGPEDRKLQKMRQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0E9E0-1", "uniprot_id": "Q0E9E0_DROME", "id": "Q0E9E0-1", "name": "", "aln": "---------MLARCVLFVTWLAVFIATGKSDDQLMKLPACAAKQGECDDNEG-PVCGTDGQTYPTRCHLLRAQCGGHQVSLKYSGSCN---------------------------------ACLEAVKFARRQQERDPGYFVPRCRKDGNFAAMQCYGNNG-CWCSDSQGRPIADDNKQFRRKGKLRCRANRRDRRRLASHQIGYNPDTSASKGSSEAGSTAHRTCSKSDRSQFNTNLMRMFRNEAQSFFRQPSLSDSHILEWQFSKLDTNGNKLLDRQEIRELKKVLRRNVKPRRCGRTFGKYCDVTKDANLNWLEWSVCFTKEFHNRSAVVNLLASSAATAPPHSTHYSIHNTNVNGHHRGHTNTIGTGVNPHSYSEDASGSEEHEDNYEDSATGYGGEEDDSQGADLPSSRTHIPSLYMLNSK-PETASQDLENDSNCWMDQSVTLEEQGHGGKSVLFVPQCLPDGRYQRIQCYSSTSTSYCWCVNEDTGKSIPGTSVKNKRPQCDESVAVR-----------PMKGCTEPRKTQFLKELKAYLNTSLLPSSTTGSNS--------SMWKTDDERIATLSFVYLDKNKNKSWDRREWKNFRDLVTSASHLRRCGKKMPRYCDVNGDKKISLAEWLNCLQATPRESATTAKPAQSNETASPKFQGVNPVERYLKD---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *.: *. .:. : : . . * .. *:*.:**::* : *. **:* . : : : * *: . * : .: :: : . *:*.* .**.*: :**: .* *** .:*:*:: *** ..*. : . . :*.* * : : :* ::.:. * * :.* .: :. *: .* ::. : :* :. :. :.:*:* * *: :**:.**. ***** ***:.:****.: *.*:. . : : **.* :* :*:..* *.*.:: : .: : : . :* :**:. * **.* ... :::* * *: *.. :: ::*.:::. ***:* ** *** * .** .. :*. ", "identical_positions": 98, "similar_positions": 145, "identity": "14.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110310-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5BKT4-1", "uniprot_id": "AG10A_HUMAN", "id": "Q5BKT4-1", "name": "Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase A", "aln": "MAQLEGYYFSAALSCTFLVSCLLFSAFSRALREPYMDEIFHLPQAQRYCEGHFSLSQWDPMITTLPGLYLVSIGVIKPAIWIFGWSEHVVCSIGMLRFVNLLFSVGNFYLLYLLFCKVQPRNKAASSIQRVLSTLTLAVFPTLYFFNFLYYTEAGSMFFTLFAYLMCLYGNHKTSAFLGFCGFMFRQTNIIWAVFCAGNVIAQKLTEAWKTELQKK-EDRLP-PIKGPFAEFRKILQFLLAYSMSFKNLSMLLLLTWPYILLGFLFCAFVVVNGGIVIGDRSSHEACLHFPQLFYFFSFTLFFSFPHLLSPSKIKTFLSLVWKRRILFFVVTLVSVFLVWKFTYAHKYLLADNRHYTFYVWKRVFQRYETVKYLLVPAYIFAGWSIADSLKSKSIFWNLMFFICLFTVIVPQKLLEFRYFILPYVIYRLNIPLPPTSRLICELSCYAVVNFITFFIFLNKTFQWPNSQDIQRFMW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5I7T1-1", "uniprot_id": "AG10B_HUMAN", "id": "Q5I7T1-1", "name": "Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase B", "aln": "MAQLEGYCFSAALSCTFLVSCLLFSAFSRALREPYMDEIFHLPQAQRYCEGHFSLSQWDPMITTLPGLYLVSVGVVKPAIWIFAWSEHVVCSIGMLRFVNLLFSVGNFYLLYLLFHKVQPRNKAASSIQRVLSTLTLAVFPTLYFFNFLYYTEAGSMFFTLFAYLMCLYGNHKTSAFLGFCGFMFRQTNIIWAVFCAGNVIAQKLTEAWKTELQKK-EDRLP-PIKGPFAEFRKILQFLLAYSMSFKNLSMLFCLTWPYILLGFLFCAFVVVNGGIVIGDRSSHEACLHFPQLFYFFSFTLFFSFPHLLSPSKIKTFLSLVWKHGILFLVVTLVSVFLVWKFTYAHKYLLADNRHYTFYVWKRVFQRYAILKYLLVPAYIFAGWSIADSLKSKPIFWNLMFFICLFIVIVPQKLLEFRYFILPYVIYRLNITLPPTSRLVCELSCYAIVNFITFYIFLNKTFQWPNSQDIQRFMW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UGP8-1", "uniprot_id": "AG10B_MOUSE", "id": "Q3UGP8-1", "name": "Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase", "aln": "MAQLEGYYFSAALSCTFLVSCLLFSAFSRALREPYMDEIFHLPQAQRYCEGRFSLSQWDPMITTLPGLYLVSVGVVKPASWLLGWSEHVICSIGVLRFVNLLFSVGNFYLLYLLFRKVQPRNKASSSIQRILSTLTLAVFPTLYFFNFLYYTEAGSVFFTLFAYLMCLYGNHRTSALLGFCGFMFRQTNIIWAAFCAGHLIAQKCSEAWKIELQKKKEERLA-PTKGPLSELRRVLQFLLVYAMSLKNLRMLFLLTWPYVLLLLAFFAFVVVNGGIVVGDRSSHEACLHFPQLFYFFSFTAFFSFPHLLSLTKVKTFLSLVWKRRVQFSVVTLVSILLVWKFTYVHKYLLADNRHYTFYVWKRVFQRHEVVKYLLVPAYIFAGWAIADSLKAKSIFWNLMFFVCLVASTVPQKLLEFRYFILPYIIYRLNIPLPPISRLVCELGCYTVVNFVTFYIFLNKTFQWPNSQDIQRFMW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FEB7-1", "uniprot_id": "E7FEB7_DANRE", "id": "E7FEB7-1", "name": "Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase", "aln": "MERFEVYIFTALCSVNFLISCLLFSKITREQRDPYMDEIFHVPQAQKYCEGKF--TEWDPMITTLPGLYLASVGLIRPVVWLADLKGRVVCSTAMLRFINLLFNSGNLYILYLIICKLHMKDKSRSASRRMLSALVLSTFPVLYFFTFLYYTDSGSTFFTLFMYLMALYGCHKVAALLGICAVLFRQTNIIWVAFCASMVVAQKLDETWRTDQSKKRDEKLPSQVPLTINGAIRVMRFLLDFLISPNNIKAVVLSTWPYIAVAFGFAFFVVLNEGIVVGDRSSHEACLNFPQFFYFLSFTLIFSLSTSLSYQRAVRFLQALKKQPLVYSFLMLTFLFLIWKFTFVHKYLLADNRHFPFYVWKNIFRRHDAVRYLLVPGYVFAMWNFLDTLRSKSLFWCLAFCACLVAATVPQKLLEFRYFIIPYLLYRVNISVPSLPRLFLEFSLYTAVNAATVYIFIYKTFQWPNNTAVQRFMW", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::* * *:* * .**:****** ::* *:********:****:****:* ::*************.*:*:::*. *: . :*:** .:***:****. **:*:***:: *:: ::*: *: :*:**:*.*:.**.****.*****::** ***** ***.*** *:.:*:**:*..:********..***. ::*** *:*: : .** :::*. .: ::::*** : :* :*: :. ****: : : * ***:* ***:**********:***:***:*** :**:. ** : **. : *: : : .: *. ::*:****:.**********:.*****.:*:*: ::*****.*:** * : *:*::*.:** * * **. ************:**::**:**.:*. .**. *:. *: ** *.:**: *******. :*****", "identical_positions": 246, "similar_positions": 140, "identity": "51.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110315-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LVM9-1", "uniprot_id": "F1LVM9_RAT", "id": "F1LVM9-1", "name": "", "aln": "MWLMAKDTGMSVASVTLASALQVRGEALSEEEIWSLLSLAAERLLEDLRNDSS--DYVVCPWSLLLSAAGSLSFQDNVSHIEAAPFKAPELLQGPDEEERPDASQTHVYSLGMTLYWSAGFRVPPKQPLQLQEPMHSLLLAMCEDQPRRRRPLQAVLEACRIHQEEVAVYPAPASLHISRLVGLVLGTISEVERRVAEENACEQRNRSCFLRSRLHQADSESPGSRAPDALQPRRVSGRSTETQSSLERCWSTTAHSRSGFN-STFAGAGPCDCEEGPRCGSGPMLLAEAESSKPATSSPRNFLHRKGKFSRPEFILLAAEAPVTLHLPGSIVTKKGKSYLALRDLRVLLLNGQCLEVKCDVESTAGAVFNAVMSFANLGETTYFGLAYVKGEEFFFLEPNTRLCKVAPEGWREQQPKSSVDTLTLFLRIKFFVSHYGLLRHSLTRHQFYLQLRKDILEERLYCNDETLLQLGVLALQAEFGSYPKEQVEGETYFQIQDYIPARLIERMTAIRVQVEVSEMHRLSPAPQGEDAELEFLEVVQQLPEYGVLVHRVSPAKKRQEGGMALGICTKGIIVYEVKGSRRTTTFQFPWRETGMISTHRRKLTVTSSTTGKKYTFVTDSAKTCKYLLGLCSSQHWFNAHMGLEQPPHLLTGQDKFAQIASLNSAHQTQANPLTWIQKLSCSENELCVPRLQNATGGQLGTAME--NMQGSKEPEMGRNRSSPYTGGEQLHSIGLNQR--PTHTLFGTAGHSTCAGS------------------QKSKRKGFMDEPNGDIMCVMLKRDPLLGFGFVIYEGEDKEQSKTGIFISSLIPGGPAERAKKIKPGGKILALNHISMEGFTFNMAVKMIQNSPDDIELIISQPKGVC---GDIPSEDKNSTASSGTFCTDILSNRCRGQQSAHTQDQDRNARGPETVQQG------------------AGSCPPSPLDA--GEIYFVELVKEDGTLGFSVTGGINTSVPHGGIYVKSIIPGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPGQVAQLVLERRGPRAAPQCP---------------SADDRMGEVHMAVSLVTAKPGRPASRVSVTDGPKFEVKLKKNSSGLGFSFVQMERGNHIHVKSDLVRIKRLFPGQPAEEHGAIAAGDIILAVNGKPIEGLAFQEVLHLLRGAPEEVTLLLCRPPPGILPEMEQGWQTPELSGDQRLTMATRAESEQSPSLDQEDNWRDSTSLDAGDGLSPRPESSYKAEKEVKGDGDKQRPWARSLMHPMESHPHLCKLHPEPETPALATSLEKDMRQNCYSVCDIRRLG------------------SSSLTLDSEGYMALTSTSAGQLPCEECLEADSETIPLPRFCSSGALLKSSLPEGSPGSESDWEDLDEPVDGDEVLRWTHSARVS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A140LI67-1", "uniprot_id": "FRPD2_MOUSE", "id": "A0A140LI67-1", "name": "FERM and PDZ domain-containing protein 2", "aln": "MRPLAKDTGMSVASVTLASALQVRGEALSEEEIWSLLSLAAERLLEDLRNDSS--DYVVCPWSLLLSAAGGLSFQDHVSHIEAAPFKAPELLQGSNEEGQPDASQMHVYSLGMTLYWSAGFRVPPNQPLQLQEPVHSLLLAMCEDQPRRRQPLQAVLEACRIHQEEVAVYPAPASLHISRLVGLVLGTISEVERRVVEENACEQRNRSCSLRSRLHQADGESPGAPASDALQPRRVSERSAETQSSLERC---TAHSRNSFVNSTFAGAGPCDCEESPWYGSEPMLLAEAESSQPATSSPRNFLQRKGKFSRPEFILLAGEAPVTLHLPGSIVTKKGKSYLALRDLCVVLLNGRCLEVKCDMESTAGAVFNAVMSFANLEETTYFGLAYVEGEEFFFLDKDTRLCKVAPEGWREQHPKGSVDTFTLFLRIRFFVGHYRLLRHSLTRHQFYLQLRKDILEERLYCNDETLLQLGVLALQAEFGSYPKEQVEGKAYFRIQDYIPARLIERMTAIRVQVEVSEMHRLSSAPWGEDAELEFLEIVQQLPEYGVLVHRVSPEKKRPEGKMALGVCTKGIIVYEVRGSRRIATSQFPWRETGMISTHRKKLTITSSTTGKKYTFVTNSSKTCKYLLGLCSSQHWFNAQTGSKHPSHRFTGQDKFAQIASLSSAHQTQANPITWIQKLSCSENELCVPRLQDATGGQLGTSME--NKQGFKEPGKERIGSSPYTGGEQLHSIGLNQK--PAQTVFGTAGHSMCAGSNCLGRRTQICCFDSVSGSQNSKRKGLFGEPNQDIVCVMLKRDPVHGFGFVINEGEDAEQTRSGIFISSLIPGGPAERAKKIKPGGKILALNHISLEGFTFSMAVRMIQNSPDDMELIISQPKGVC---GTIHSEEKNSTASSGMFCTDILSNRCQGRQSPHIHDQDRSVRG-TEMAQG------------------AGSCPPSPLQTNTGEIYFVELVKEDGTLGFSVTGGINTSVPHGGIYVKSIIPGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPGQVARLVLERRGPRAAPQCP---------------SADDRMGDVHMAVSLVTARPGRPASSVSVTDGPKFEVKLKKNSRGLGFSFVQMERGNCIHTKSDLVRIKRLFPGQPAEEHGAIAAGDIILAVNGKPIEGLAFQEVLHLLRGAPEEVTLLLCRPPPGILPEMEPGWQTPELSGDQRLTMATCAGSEQSPSLDQEDNWRDSTSLDAGEGLSPGPESSYKDVRQVKGDREKERPWAKSWMHPMESHPHVCKLHPEPETPALATSLEKDMRQNCYSVCDIRRLGSLELDRDGADGATCFLPESSSLTVDYEEYLTLTSASAGQLPCEECLEADSETIPLPQFCSLGALLKSSLPEESQGSESDWEDLDEPVDRDEVLRWTRSARQPLAAEP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q68DX3-1", "uniprot_id": "FRPD2_HUMAN", "id": "Q68DX3-1", "name": "FERM and PDZ domain-containing protein 2", "aln": "MQPLTKDAGMSLSSVTLASALQVRGEALSEEEIWSLLFLAAEQLLEDLRNDSS--DYVVCPWSALLSAAGSLSFQGRVSHIEAAPFKAPELLQGQSEDEQPDASQMHVYSLGMTLYWSAGFHVPPHQPLQLCEPLHSILLTMCEDQPHRRCTLQSVLEACRVHEKEVSVYPAPAGLHIRRLVGLVLGTISEVEKRVVEESSSVQQNRSYLLRKRLRGTSSESPAAQAPECLHPCRVSERSTETQSSPEPHWSTLTHSHCSLLVNRALPGADPQDQQAGRRLSSGSVHSAADSSWPTTPSQRGFLQRRSKFSRPEFILLAGEAPMTLHLPGSVVTKKGKSYLALRDLCVVLLNGQHLEVKCDVESTVGAVFNAVTSFANLEELTYFGLAYMKSKEFFFLDSETRLCKIAPEGWREQPQKTSMNTFTLFLRIKFFVSHYGLLQHSLTRHQFYLQLRKDILEERLYCNEEILLQLGVLALQAEFGNYPKEQVESKPYFHVEDYIPASLIERMTALRVQVEVSEMHRLSSALWGEDAELKFLRVTQQLPEYGVLVHQVFSEKRRPEEEMALGICAKGVIVYEVKNNSRIAMLRFQWRETGKISTYQKKFTITSSVTGKKHTFVTDSAKTSKYLLDLCSAQHGFNAQMGSGQPSHVLFDHDKFVQMANLSPAHQARSKPLIWIQRLSCSENELFVSRLQGAAGGLLSTSMDNFNVDGSKEAGAEGIGRSPCTGREQLKSACVIQKPMTWDSLSGPPVQSMHAGS------------------KNNRRKSFIAEPGREIVRVTLKRDPHRGFGFVINEGEYSGQADPGIFISSIIPGGPAEKAKTIKPGGQILALNHISLEGFTFNMAVRMIQNSPDNIELIISQSKGVG---GNNPDEEKNSTANSGVSSTDILSFGYQGSLLSHTQDQDRNTEELDMAGVQSLVPRLRHQLSFLPLKGAGSSCPPSPPEISAGEIYFVELVKEDGTLGFSVTGGINTSVPYGGIYVKSIVPGGPAAKEGQILQGDRLLQVDGVILCGLTHKQAVQCLTGPGQVARLVLERRVPRSTQQCP---------------SANDSMGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPELEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESSQKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCDIMRLG------------------------RYSFSSPLTRLSTDIF-------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6IN97-1", "uniprot_id": "FRP2L_HUMAN", "id": "Q6IN97-1", "name": "Putative protein FRMPD2-like", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTSIPFP---------------------GDRLLQVDGVILCGLTHKQAVQCLKGPGQVARLVLERRVPRSTQQCP---------------SANDSMGDERTAVSLVTALPGRPSSCVSVTDGPKFEVKLKKNANGLGFSFVQMEKESCSHLKSDLVRIKRLFPGQPAEENGAIAAGDIILAVNGRSTEGLIFQEVLHLLRGAPQEVTLLLCRPPPGALPEMEQEWQTPELSADKEFTRATCTDSCTSPILDQEDSWRDSASPDAGEGLGLRPESSQKAIREAQWGQNRERPWASSLTHSPESHPHLCKLHQERDESTLATSLEKDVRQNCYSVCDIMRLG------------------------RYSFSSPLTRLSTDIF-------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GWI9-1", "uniprot_id": "A0AC58GWI9_DANRE", "id": "A0AC58GWI9-1", "name": "", "aln": "----------MSTFVTLAEVLESRAAPLEEDEVWALLLGATEALIDISSKDDGNMCCVISPGSMLLSAVGSIAFKTCSRSEDVGSFTCPEMSQSNTSSRRLASEKMVVYSLGMTLYWAVDYNLPQNQPVQVSDTLNSLLLSMCEDVAHRRVNLLTVLETAENHHQTAVLPRP------EKTIRQMAEDVLQTEK--PSNDSAHLIDRSQMVRERLRGASSQNSVWTQ---------KGNSTPSAADFSRFHSSHQRSRNSTYMSQSP--------------VLDRRRQFALRPDQLFASSFSLNERKMKDTGPEFIRMLEEPLVVLELPNSIVSNKGKSSSNQRDLTVLMPNGQNVLLKCDVKCRGRDAFDMIVAHTNLVEHFYFGLAYSYDNEFFFLDNDTKISKVAPGVWKKVP----TATFVLHFRIKYFVSDVSLLLNKFTRHQFYLQLRRDLLDDRLQCNEETCLFLGALALQAEFG-DSLPEVYGKNYYQPEHYVSKSVVQKMAMPCLKEELLRLHVNNANMSAEEAELEFLKSVQQLPEYGVLFHRVAREKKPVFGELLLGVCAKCITVYEVINNCRTASLTFHWRDTSSITSTRRKFIIECSTSKKKHVFLTEKSKVAKYLCDLCSAQHKFHKEMSSRQLTHSLASEESIVQYAALCRAQNNEVNDSSADESMSKLCEDIATR-----IEAKIKLQRDLLDNPGSQSPVLQRSLCSTPKRGSDVPSVSSPLRDTPTGAR----------------------------------------TPEREIICVSLKKDPKVGLGIVIVGEDTAGKLDLGIFIASVVPGSPADRDGRIKPGGRLISLNQLSLEGMSFSEAADIMQSSSNDVELIISQPKAQCKRGGSVSLNERSYESQSTILADGRTGDEFLDELVSVMMTPKASNRLHVPEVRIIN--------------AQDDYSRSASLISLRPEEFTVTLMKSGGSLGISIAGGVNTGLRYGGIYIKSLVSGGVAEQDGRIQTGDRLLEVDGIRLQGFTDQQAAECLARTGEVVGLVLERDGGSMLQRGPGSPQLRNTLSICTPGPAGTQARKSCPAITMTRPFNIKPRDYSFVSDDNIQEVTLKKRLNGLGFSFFISELN-TSRDRGSIVRIKTLFPGQPAEESGRIQEGDVILSINGEPLKGLSYQHVLQLLRNSPSEVRMLLCRPAQGTLPAVSEKIGQLTCS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.: . *****:***: * *:*.:**.:** .*:*. ***** : * .*. . *:::. . :* . *:*. **.***. ******. * : :..:**** ********* * * **:**::**.. :** :*.**:***.:*.** :*****. * ** :. * ", "identical_positions": 82, "similar_positions": 50, "identity": "5.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110316-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60773-1", "uniprot_id": "CDN2D_MOUSE", "id": "Q60773-1", "name": "Cyclin-dependent kinase 4 inhibitor D", "aln": "-MLLEEVCVGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSPAVALELLKQGASPNVQDASGTSPVHDAARTGFLDTLKVLVEHGADVNALDSTGSLPIHLAIREGHSSVVSFLAPESDLHHRDASGLTPLELARQRGAQNLMDILQGHMMIPM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55273-1", "uniprot_id": "CDN2D_HUMAN", "id": "P55273-1", "name": "Cyclin-dependent kinase 4 inhibitor D", "aln": "-MLLEEVRAGDRLSGAAARGDVQEVRRLLHRELVHPDALNRFGKTALQVMMFGSTAIALELLKQGASPNVQDTSGTSPVHDAARTGFLDTLKVLVEHGADVNVPDGTGALPIHLAVQEGHTAVVSFLAAESDLHRRDARGLTPLELALQRGAQDLVDILQGHMVAPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I3ISM6-1", "uniprot_id": "I3ISM6_DANRE", "id": "I3ISM6-1", "name": "Cyclin-dependent kinase 4 inhibitor D", "aln": "MMVLDGLGCGKSLSAAAAQGDARAVRRILQDHRVEPDALNEFGKTALQVMMMGSSAVAAVLLDFGADPNVQDRSGVTPAHDAARTGFLETLRVLVDGGASVNVPDHSGALPLHIAVREGHWDVVEYLAPLTELRWLDG-----------RRVEELLEHLQATGSG--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*: : *. **.***:**.: ***:*: . *.*****.**********:**.*:* **. **.***** **.:*.*********:**:***: **.**. * :*:**:*:*::*** **.:**. ::*: *. * .::*:: **. ", "identical_positions": 83, "similar_positions": 45, "identity": "49.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110316-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C6B9-1", "uniprot_id": "AROS_MOUSE", "id": "Q8C6B9-1", "name": "Active regulator of SIRT1", "aln": "MSAALVRRGLELLAASEAPRAVPGQVQASGTPAKRTRRARAKASQALKLRNSAKGKAPKSALAEYQKRQCRDHLKANLKFMTSMRSTVPESVTQQILQQNQGRKACDRLVAKTKNKKKKKKKAEGTVFTEEDFQKFQREYFGS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86WX3-1", "uniprot_id": "AROS_HUMAN", "id": "Q86WX3-1", "name": "Active regulator of SIRT1", "aln": "MSAALLRRGLELLAASEAPRDPPGQAKPRGAPVKRPR--KTKAIQAQKLRNSAKGKVPKSALDEYRKRECRDHLRVNLKFLTRTRSTVAESVSQQILRQNRGRKACDRPVAKTK-----KKKAEGTVFTEEDFQKFQQEYFGS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F0U9-1", "uniprot_id": "E7F0U9_DANRE", "id": "E7F0U9-1", "name": "Active regulator of SIRT1", "aln": "MSASVIRRGLELFSEKDGAKHKQ---KRNSSSKKRIRQLQRAGQSSQSNNNTVKDKHIRSAVDEYRKKQKKSQLSSNLKYFLRTSSTTQKQHTAKEVQQSSSRRSCDQPDLPEA------KPKETSVFTEQEFQTFQQEYFSRL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:::******:: .:..: : .:. ** * : . .: . .*:.*.* :**: **:*:: :.:* ***:: **. :. : : ::*. .*::**: * * :****::**.**:***. ", "identical_positions": 43, "similar_positions": 51, "identity": "29.86%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110317-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ESM0-1", "uniprot_id": "IP6K1_RAT", "id": "Q9ESM0-1", "name": "Inositol hexakisphosphate kinase 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCVCQTMEVGQYGKNASRAGDRG----------VLLEPFIH----QVGGHSSMMRYDDHTVCKPLISREQRFYESLP------PEMKEFTPEYKGVVSV--CFEGD------SDGYINLVAYPYVESETVEQ--------------------------------------------------DDTPEREQP--------------------------------------RRKHSRRSLHRSGSGSDHKEEK------------------------------------------------ASLSFETSESSQETKSPKVELHSHSDVPFQMLDSNSG-------------------------------------------------------------------------------------LSSEKISYNPWSLRCHK----QQLSRMRS--------------ESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEKAARQMRKCEQSTSASLGVRVCGMQVY---------------QLDTGHYLCRNKYYGRGLSI-EGFRNALYQYLHNGLDLR--RDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SELRLKHVDMGLPEVPPLCGPS----------------------------------------------------------------------TSPSNTSLEAGPSSPPK--------------------------------------------------------------------------------------------------------------------------VDVRMIDFAHSTFKG-----------FRDDPTVHDGPDRGYVFGLENLISIMEQMRDENQ------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6PD10-1", "uniprot_id": "IP6K1_MOUSE", "id": "Q6PD10-1", "name": "Inositol hexakisphosphate kinase 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCVCQTMEVGQYGKNASRAGDRG----------VLLEPFIH----QVGGHSSMMRYDDHTVCKPLISREQRFYESLP------PEMKEFTPEYKGVVSV--CFEGD------SDGYINLVAYPYVESETVEQ--------------------------------------------------DDTPEREQP--------------------------------------RRKHSRRSLHRSGSGSDHKEEK------------------------------------------------ASLSFETSESSQEAKSPKVELHSHSDVPFQMLDSNSG-------------------------------------------------------------------------------------LSSEKISYNPWSLRCHK----QQLSRMRS--------------ESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEKAARQMRKCEQSTSATLGVRVCGMQVY---------------QLDTGHYLCRNKYYGRGLSI-EGFRNALYQYLHNGLDLR--RDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SELRLKHVDMGLPEVPPPCGPS----------------------------------------------------------------------TSPSSTSLEAGPSSPPK--------------------------------------------------------------------------------------------------------------------------VDVRMIDFAHSTFKG-----------FRDDPTVHDGPDRGYVFGLENLISIMEQMRDENQ------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92551-1", "uniprot_id": "IP6K1_HUMAN", "id": "Q92551-1", "name": "Inositol hexakisphosphate kinase 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCVCQTMEVGQYGKNASRAGDRG----------VLLEPFIH----QVGGHSSMMRYDDHTVCKPLISREQRFYESLP------PEMKEFTPEYKGVVSV--CFEGD------SDGYINLVAYPYVESETVEQ--------------------------------------------------DDTTEREQP--------------------------------------RRKHSRRSLHRSGSGSDHKEEK------------------------------------------------ASLSLETSESSQEAKSPKVELHSHSEVPFQMLDGNSG-------------------------------------------------------------------------------------LSSEKISHNPWSLRCHK----QQLSRMRS--------------ESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTRQHGDDASAEKAARQMRKCEQSTSATLGVRVCGMQVY---------------QLDTGHYLCRNKYYGRGLSI-EGFRNALYQYLHNGLDLR--RDLFEPILSKLRGLKAVLERQASYRFYSSSLLVIYDGKECRAES---------------------------------------------------------------------------------------------------------------------------------------------------------------------CLDRRSEMRLKHLDMVLPEVASSCGPS----------------------------------------------------------------------TSPSNTSPEAGPSSQPK--------------------------------------------------------------------------------------------------------------------------VDVRMIDFAHSTFKG-----------FRDDPTVHDGPDRGYVFGLENLISIMEQMRDENQ------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RE97-1", "uniprot_id": "F1RE97_DANRE", "id": "F1RE97-1", "name": "Kinase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCVPHTMEAGKHSASQGQGSCGG----------VPLEPFIH----QVGGHTSMMRYDDHTVCKPLITREQRFYESLP------PEMKEFTPEYKGVVLV--CFEGD------SDGYINLVAYPYEESEGLDH--------------------------------------------------EELSERDQP--------------------------------------RRKHSRRSLHRSS--SEHKEDR------------------------------------------------HAHDSDGNDNLQELKSPLLDLQLHSDVPFQMLDSNSG-------------------------------------------------------------------------------------LSSEKISHNPWSLRCHK----QQLSRMRS--------------ESKDRKLYKFLLLENVVHHFKYPCILDLKMGTRQHGDDASEEKAARQMKKCEQSTSATLGVRVCGMQVY---------------QMDTGHYLCRNKYYGRSLSI-DGFRQALFQFMHNGTLLR--KDLFEPVLSKLCSLKAVLERQASYRFYSSSLLIIYEGKDPE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SADSWQKPSE-LPSAKENQATS----------------------------------------------------------------------SENPAASELHTPPQVLN--------------------------------------------------------------------------------------------------------------------------VDVRMIDFAHSTFKG-----------FRDDQTVHDGPDRGYVFGLESLINILQEIREENQ------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2E9-1", "uniprot_id": "Q9W2E9_DROME", "id": "Q9W2E9-1", "name": "Kinase", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVYFLGDWGMGDSDLSSYQQHVPN----------IQQPRRIHGHDLLLQQQQQQLPQQQQQQQQQQQQQQQEFVAQIS------SSLSQVQAQLQFASGS--SFLQQGSSPSPSQQQHGPVSSSSLVTANLQQ--------------------------------------------------LSVSSSNAS--------------------------------------SSSSNNNSASGCNTPTKPQKQKPLLLPE----------------------------------------AAASTATAVGKSSKNPQLSKDLLDNEDEVALHPLSNQVGGHTRLLLLNQSTVIKPLNLRE------------LDFYQNIPQDILKFVPKYKGVMQATTMGGAKLDKRYSPSFRDDAAAVPVRKMSASKRKRDEVLRMKVHKNGQAAEVIKSIS--------------QLDNTNKQYFLMLENITSQFRNPCILDLKMGTRQHGDDASAEKRSKQMAKCAASTSGSLGVRLCGMQTY---------------LADLEQYAKRDKYWGRELNE-GGFKTALHDFFHNGYRLR--IRVIRKILQRLLQLRRVIEKQSSYRFYSCSLLIVYEGFEENPMAPPPSMSQDEWPEAPRSATVPGTVFDYHPENSIDEDDLEDDDEAGNEAGDELEAHDTDDDLHLVAADSGNASATNSSTGGDACNYDADASNDSNSLLNLATRRHLHKRGFAEAAARGVKQTASHNTTTDEEEEDEHPAMPPPRTCGVMAAKAAAAAAGLAGKGQGAFIPISEETVFLDPEPALPSVTTSSPHSGDSWMNYSSNSSDDFSGLSEQIKAVASGRQTCNNSSDDASSDYESSIIGPTEAMFKRYKSQQSFDAATAADSASSPPLTAGNSSVSNGGTTVRSLVSPASSSASSLKSVKGAVKRLRCNDDDQQSASLGESDLREAKKSTITSTPVSAVSSPAKAAPQLRSCESISNQQSLLSGLLLDNNNEQRRNALLQQSSKSLDMSAPPTDDNQCFVDVRLIDFAHTAFVPR----NGTMLPTPAAAPVHHGPDGGFLTGLDSLNRLLNEIVAEERA-----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12494-1", "uniprot_id": "KCS1_YEAST", "id": "Q12494-1", "name": "Inositol hexakisphosphate kinase 1", "aln": "MDTSHEIHDKIPDTLREQQQHLRQKESEGCITTLKDLNVPETKKLSSVLHGRKASTYLRIFRDDECLADNNNGVDSNNGGSVTCADKITRSEATPKSVPEGLQVSEKKNNPDTLSSSLSSFILSNHEEPAIKPNKHVAHRNNITETGQGSGEDIAKQQSHQPQVLHHQTSLKPIQNVDEGCISPKSTYQESLHGISEDLTLKPVSSATYYPHKSKADSGYEEKDKMENDIDTIQPATINCASGIATLPSSYNRHTFKVKTYSTLSQSLRQENVNNRSNEKKPQQFVPHSESIKEKPNTFEQDKEGEQADEEEDEGDNEHREYPLAVELKPFTN----RVGGHTAIFRFSKRAVCKALVNRENRWYENIEL---CHKELLQFMPRYIGVLNVRQHFQSKDDFLSDLDQENNGKNDTSNENKDIEVNHNNNDDIALNTEPTGTPLTHIHSFPLEHSSRQVLEKEHPEIESVHPHVKRSLSSSNQPSLLPEVVLNDNRHIIPESLWYKYSDSPNSAPNDSYFSSSSSHNSCSFGERGNTNKLKRRDSGSTMINTELKNLVIREVFAPKCFRRKRNSNTTTMGNHNARLGSSPSFLTQKSRASSHDASNTSMKTLGDSSSQASLQMDDSKVNPNLQDPFLKKSLHEKISNALDGSHSVMDLKQFHKNEQIKHKNSFCNSLSPILTATNSRDDGEFATSPNYISNAQDGVFDMDEDTGNETINMDNHGCHLDSGKNMIIKSLAYNVSNDYSHHDIESITFEETSHTIVSKFILLEDLTRNMNKPCALDLKMGTRQYGVDAKRAKQLSQRAKCLKTTSRRLGVRICGLKVW---------------NKD--YYITRDKYFGRRVKVGWQFARVLARFLYDGKTIESLIRQIPRLIKQLDTLYSEIFNLKGYRLYGASLLLMYDGDANKSNSKRKKAAN----------------------------------------------------------------------------------------------------------------------------------------------------VKVNLIDFARCVTKEDAMECMDKFRIPPKSPNIEDKG-----------------------------------------------------FLRGVKSLRFYLLLIWNYLTSDMPLIFDEVEMNDMIS---------------------------------------------------------------------------------------------------------------------EEADSNSFTSATGSKINFNSKWDWLDEFDKEDEEMYNDPNSKLRQKWRKYELIFDAEPRYNDDAQVSD", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P07250-1", "uniprot_id": "IPMK_YEAST", "id": "P07250-1", "name": "Inositol polyphosphate multikinase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDTVNNYRVLEHKAAGHDG--------------------------------TLTDGDGLLIFKPAFPQELEFYKAIQVRDVSR--------------------------------------------------------------------------------------------------RKSSADGDAP---------------------------------------------------------------------------------------------------------------LCSWMPTYLGVLNEGAKIEQSGDAALLKIDERLS-------------------------------------------------------------------------------------DSTDNLDSIPVKSEKSK----------------------------------QYLVLENLLYGFSKPNILDIKLGKTLYDSKASLEKRERMKRVSETTTSGSLGFRICGMKIQKNPSVLNQLSLEYYEEEADSDYIFINKLYGRSRTD-QNVSDAIELYFNNPHLSDARKHQLKKTFLKRLQLFYNTMLEEEVRMISSSLLFIYEGDPERWELLN------------------------------------------------------------------------------------------------------------------------------------------------------------------------DVDKLMRDDFIDDDDDDDDNDD---------------------------------------------------------------------DDDDDAEGSSEGPKDKKTTGS----------------------------------------------------------------------------------------------------------------------LSSMSLIDFAHSEITP------------------GKGYDENVIEGVETLLDIFMKF-----------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : :: .: : . .. : . . .:..: . . . : . * :::**:: : * **:*:*. :. .*. * . :** **.*:**:: * :* :** . . .: :: : : : : * *: ..***.:*:* . . . . . . : * .. : . :: ", "identical_positions": 29, "similar_positions": 74, "identity": "2.08%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110318-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZA00-1", "uniprot_id": "D3ZA00_RAT", "id": "D3ZA00-1", "name": "V-type proton ATPase subunit S1", "aln": "----------------------MGRKLLFSFSLLFLCMVFSVSLDQILARKN------------------VGSQASSSKEAIVPNGQRNSGEVKPVQNLTTVPITQTFNYNLSKAHWSTFSHHN------PVKFSRDGIP-----------------CILFWTKRITVKFKNQTWLDLTDEALGQNTTVDTGNSNCSEENAVIKQMRKSKHRLWRTVRLSLKFGDAENPKDIDIRFTLSN-YIKLSSQSWFSLHRVEIIFNNSVQATFNATGIYALSTYSYHCQRVSSLRRND---ALLLLSSSDDVTSLWEVTFIDFQIQG-FS---IKGAQFSQARDCSSSFSPAVLIGLAMSLILLLVLAYALHMLIYLRYLDHHYEFITSPAHFPSLRALDIGEEKELLGSQGAECYELRNQQICKIYI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z5W0-1", "uniprot_id": "D3Z5W0_MOUSE", "id": "D3Z5W0-1", "name": "V-type proton ATPase subunit S1", "aln": "----------------------MGRKLLFSFSLLFLCMVFSVSLDQILARKN------------------VGSQESSSKEVVVRNGQKNSGEVKPVQNFTRIPIAQTFNYNLSNKPWSTFSHHN------PVQFSRDGIP-----------------CILFWTKRITVKFKNQTWLDLTDEALGQNTTVDTGNSNCSEE----------------SATLSLKFGDDEDPKDIDIRFTLTN-YNKLASQSWFSLHRVEIIFNNSVQATFNATGIYALSTYSYRCQRVSSLRRND---ALLLLSSSDDVTSLWEVTFIDFQIQG-FS---IKGAQFAQARDCSSSFSPAILIGLAMSLILLLVLAYALHMLIYLRYLDRHYEFITSPDHFPSLRALDTGEEKELLGSQGAECYELRNQQICKIYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q52LC2-1", "uniprot_id": "VAS1L_HUMAN", "id": "Q52LC2-1", "name": "V-type proton ATPase subunit S1-like protein", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------MRLWKARVLKLVLKT----AKDSRLGLN-----------------------------SKWLSLKLGDAGNPRSLAIRFILTN-YNKLSIQSWFSLRRVEIISNNSIQAVFNPTGVYAPSGYSYRCQRVGSLQQDQ---ALLLPSDTDDGSSLWEVTFIDFQIQG-FA---IKGGRFTKAQDCASSFSPAFLIGLAMSLILLLVLAYALHMLIYLRYLDQQYDLIASPAHFSQLKARDTAEEKELLRSQGAECYKLRSQQISKIYV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13AAZ5-1", "uniprot_id": "A0AB13AAZ5_DANRE", "id": "A0AB13AAZ5-1", "name": "", "aln": "--------------------MASTWRPMSLALFSFVFLQISSSYEQLSAFVE------------------GSSDDAPSRDISIQDGGSGSSSSLSAAEAPLRRALQPYGWQLDVPPRRKLLQSPGLLLYSPLSVTYNGKT-----------------CILFRARKLAIRYRNHSLVDLTEKTFSPDAPLDTKGSFCSKD----------------KAILNLRFGDVEDLRGLSIRLQMSNTFYESAGQNWFTLDNVHIHYNWTYEATFNATDVYAPSTNSYHCQHVSSLQKYD---TLLVPSANTDHAANWHITFTDFQIQA-FN---VQSSKFAPASDCATFFTPAILMGLITSLILLLVLAYALHMVVHLKHIDR-YEEHKTTVYFPRSTEAECTEKNNL---------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7JR49-1", "uniprot_id": "VAS1_DROME", "id": "Q7JR49-1", "name": "V-type proton ATPase subunit S1", "aln": "MLWKSLIALCVIGAAVAEQTPVFLWGANSVAKPSLKTVSQVEFAEQLAALLEDHMVVAFEENGLSSKDFLCSNSQAQSCYAQLQGVSPKTYYTSVENPSEALRSVAAKREHNSIDASGKLTTPAKCAVGTALFVTFEDAAESREASLESHDAAIAAISKQFECKVAYLYLAAPSTAPVVQRRTRRDTAATTGGIMWKSTN-------------QFQIFYTALLYNGNPITVTDLKLTNSS-STKLSVVMDTSVADKPITFDVVYNGGYFSLSNLVYDNNNFRSSGVNAPTTFSYSCGNLTLESAAVNNMYNTLSFKSLQLQAPFDGTYKEDFPFGDSWDCVGFVTPGILMGLFVVALLLVIMFVGVCWMMDINTMDRFDDPKGKTITINAAAE------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : . : : ::: :. : : :: * : :. : . . . . .::.. *.: . * . ::* .:*:*. * :. * : ** .:*..*:** :**::: .: :: :. :*: : .. : ", "identical_positions": 17, "similar_positions": 62, "identity": "4.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110321-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66H89-1", "uniprot_id": "CEP83_RAT", "id": "Q66H89-1", "name": "Centrosomal protein of 83 kDa", "aln": "------------MDTFPSIFPPG----------GDSRLN-PEPEFQSMLIDERVRCEHHKHNYQALKIEHKRLQEEYVKSQNELKRVLNEKQTNQEKFQLLLEELRGELVEKVKDMEAMKLQILTPQKLELVKAQLQQELEAPMRERFRTLDEEVERYRAEYNKLRYEHTFLKSEFEHQKEELTRISEEEKMKYKSEVARLEKDKEELHNQLLSVDPTRDSKRVEQLVREKTHLLQKLKSLEAEVAELRAEKENSGAQVENVQRIQVRQLAEMQATLRSLEAEKQSAKLQAERLEKELQSSNEQNTCLISKLHKADREISTLTSQVKELKHANKLEITDVKLEAARAKSELERERNKIQSELDGLQSDNEILKSTVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVLQDEKLELENRLSDLEKMKVEHDVWRQSEKDQCEEKLRASQAAEEAARRELQSIRLKLQQQIVNTEKAEKEKLENSELKQQISHLQIQVTSLTQSENDLLNSNQMLKDMVERLKQECRHLRSQAEKVQLEVEKTLEEKQIQWLEEKHKLHERITDREEKYNQAKEKLQRAATAQKKRKSLHENKLKRLQEKVEVLEAKKEELETENQVLNRQNVPFEEYTRLQKRLKDIQRRHNEFRSLILVPNMPPAASVNPANFQSSAIVPGVELSFPPHLQEEQHQRELSLLRKRLEELETTQRKQLEELGSPGE-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D5R3-1", "uniprot_id": "CEP83_MOUSE", "id": "Q9D5R3-1", "name": "Centrosomal protein of 83 kDa", "aln": "------------MDTFPSLFPPG----------GDSRLN-PEPEFQNMLIDERVRCEHHKHNYQALKIEHKRLQEEYVKSQNELKRVLIEKQASQEKFQLLLEDLRGELVEKARDIEKMKLQVLTPQKLELVKAQLQQELEAPMRERFRTLDEEVERYRAEYNKLRYEYTFLKSEFEHQKEEFTRVSEEEKMKYKSEVARLEKDKEELHNQLLSVDPTRDSKRMEQLVREKTHLLQKLKSLEAEVAELRAEKENSGAQVENVQRIQVRQLAEMQATLRSLEAEKQSAKLQAERLEKELQSSNEQNTCLISKLHRADREISTLASEVKELKHANKLEITDIKLEAARAKSELERERNKIQSELDGLQSDNEILKSTVEHHKALLVEKDRELIRKVQAAKEEGYQKLMVLQDEKLELENRLSDLEKMKVERDVWRQSEKEQCEEKLRASQMAEEAARRELQSTRLKLQQQIVNTEKAEKEKLENSELKQQISHLQIQVTSLTQSENDLLNSNHMLKDMVERLKQECRNLRSQAEKAQLDVEKTLEEKQIQWLEEKHKLHERITDREEKYNQAKEKLQRAATAQKKRKSLHENKLKRLQEKVEVLEAKKEELETENQVLNRQNVPFEEYTRLQKRLKDIQRRHNEFRSLILVPNMPPTASISPANFQSAVTVPGAELSFPPHLQEEQHQRELSLLRKRLEELETTQRKQLEELGSPGE-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y592-1", "uniprot_id": "CEP83_HUMAN", "id": "Q9Y592-1", "name": "Centrosomal protein of 83 kDa", "aln": "----MVVSTFTDMDTFPNNFPPG----------GDSGLTGSQSEFQKMLIDERLRCEHHKANYQTLKAEHTRLQNEHVKLQNELKHLFNEKQTQQEKLQLLLEELRGELVEKTKDLEEMKLQILTPQKLELLRAQIQQELETPMRERFRNLDEEVEKYRAVYNKLRYEHTFLKSEFEHQKEEYARILDEGKIKYESEIARLEEDKEELRNQLLNVDLTKDSKRVEQLAREKVYLCQKLKGLEAEVAELKAEKENSEAQVENAQRIQVRQLAEMQATVRSLEAEKQSANLRAERLEKELQSSSEQNTFLINKLHKAEREINTLSSKVKELKHSNKLEITDIKLETARAKSELERERNKIQSELDGLQSDNEILKAAVEHHKVLLVEKDRELIRKVQAAKEEGYQKLVVLQDEKLELENRLADLEKMKVEHDVWRQSEKDQYEEKLRASQMAEEITRKELQSVRLKLQQQIVTIENAEKEKNENSDLKQQISSLQIQVTSLAQSENDLLNSNQMLKEMVERLKQECRNFRSQAEKAQLEAEKTLEEKQIQWLEEKHKLHERITDREEKYNQAKEKLQRAAIAQKKRKSLHENKLKRLQEKVEVLEAKKEELETENQVLNRQNVPFEDYTRLQKRLKDIQRRHNEFRSLILVPNMPPTASINPVSFQSSAMVPSMELPFPPHMQEEQHQRELSLLRKRLEELETTQRKQLEELGSSGE-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IVY9-1", "uniprot_id": "A0A0R4IVY9_DANRE", "id": "A0A0R4IVY9-1", "name": "", "aln": "MDKMNPPALGQASALFPDLEPPGGVGKATVLLGGSTGLTSSDMEFQKMLIDERMRCENHKTNYQTLKVEHTRLQDQYTRAQNELKRLLSDRQVTQEKQQLLLAELRGELLDKTRDLEELKLQVLTPQRLELLRAQVQQELEAPIRERFNKLQEEAENYRSEYNKLRYDLTFLKSEFDHQKEEHARVLEERRIRHEADVARLEHDKEDLATQLQSGDPARDGKRVEALLREKAQLHQRLRGLEAEVTELRAERNNSGAQAENVQRIQIRQLAESQAAVKALEAEKQSIRMQLDRTESELRLSQEQNTLLTGKLHKAEREINSLNSQVEEMKHTHKLELSNVKLECVRSKGELERERDMLQCQVEGLQSDIEVMKSALERNKELISEKEREMVRRVQAAREEEIHKMATLQEEKLELENRLSELEQQKALQEVTGNSQKEEWEERLRAAQLGEESVRKELQNLRTKVQQQGQQLEELETLKAENADLRQQIAELNLQVGTLSHSESELLDTNNRLRESLERVREDLRSARTQMERTQQEAERLVEERRVEWLEEKHKLQDIEAELREKYSQAKERLQRAAFAQKKRKTMTELKENKLKDKIQLLEAKIAELEIEASAEKKKSSYSEEHAQLSKRLRELQRRHNEFRRLLLGNQMT-----SSTPLAQSLLIP--NESIFSNIQEEQHQRELCVLRRRLEELENSQQQQLEELAAPLDRDRERLSSPRDALPDLS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **. *** *.: *. .: ***.******:***:** ***:** **.***:::.: *****::: ::*. *** **** :*****::*.:*:* :***:****:***::**:*****:*:****..*:**.*.**: ******: *******:***** :*: :* ::::::::****.***:* .** . * ::*.**:* * ***. * *:*:.*****:**:**::** **.**.****:***** **::::******* .:: :* *.**: *.**** * .***:*:***.:* *:*:*:**::***::::*** .*:*.******: :*.:::***** *::*:::*::* *: **:**::*:****:** :*: .**:*********::**: *. ::* :*:*:: **:***:* .** .*:***. * *:*** *: *. * **::*:***: *::** :*::**.:**::*: *:: :**:::: * *:* *:.* :.*: :**::::********:: :: .***.****:***** ******:: * * ::*::*:::**** *** * .. :::. *::::*.***:::******** *:* :*. ... : .: :* : .: .::*********.:**:******.:*::*****.:. : ", "identical_positions": 356, "similar_positions": 233, "identity": "48.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110324-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JX31-1", "uniprot_id": "A0A0G2JX31_RAT", "id": "A0A0G2JX31-1", "name": "Protection of telomeres protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MSLVP-----VTPYTYTPLNLLKEGAVANVYGVVKFFKPPYLSKGTDYCSVVTIVDPTNVKLTCMLFSGNYEALPIIYKVGDIVRFHRLKIQVYKNELQGINSSGFASLTFEGTLGTPVTARTSSKVFSFTSQDQKMVEALRVWASKHIAASSSLVQLCDAQPLQYYDLTCQLLGKAEVDGTAFLLKVWDGTRTMFPSWRVSIQNLTFEGDLSHIQRLQSLVIDILVYDNHVQVAKSLKIGSFIRIYSLHTKLQSVDSETSKS-LLRLEFHLHGGTSYGRGIRVLPDESSCVDQLKKDLEC-ADSAVTQPSNGICQSKNED-SFVLSSSASGSVSLYEEERCQQVSSTILTDHQHLEKTPLCAVLKQKAPQQYRVRAKLRSYLPRRLPQSVKLICPQCHSLQEVPHEDSLDKLLQDAATKAPDIRLQGTSLYESKIWTTEGQGGRQVAVHFVKKDGVLPLSSECLILIEGGRLCEVSKLSSKFHSVIPVRSGPEDLELLDISAPFLIQGKLHHYGCKQCSSLKPIQNLNSLLNKGPWIPSSVAKVLGIVPLQYVFVMTFTLDDGTGVLDTYLKD-SENFFKIPASEVLTDDNLQRNLEAIMDMICPPGIKVDAYPWLECLIKSYNVTIGTEQRICYQIFDTTVAEDV-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WC1-1", "uniprot_id": "POTE1_MOUSE", "id": "Q91WC1-1", "name": "Protection of telomeres protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MSLVS-----TAPYTYTPLNLLKEGTIANVYGVVKFFKPPYVSKGTDYCSVVTIVDQTNVKLTCMLFSGNYEALPIIYKVGDIVRFHRLKIQVYKNELQGINCSGFASLTFEGTVGMPVTARTSSKVFSFTPQDQKMVEALRVWASKHISASSTLVQLCDAQPMQYYDLTCQLLGKAQVDSTAFLLKVWDGTQTVLPSWRVSTQDLTFEGDLSHIERLQSLVVDILVYDNHVQVARSIEVGCFLRLYSLHTKLQPGNSETSSSESLRLEFHLHGGTSYGRGIRVLPDTSPCVDQLKKALEG-ANLPVTETSTGICQSENGD-SSALSNSGSGAVSPYEEERCQQVSATILTNHQHLEKTPLCAILTQKAPQQYRVRAKLRSYLPRRLSQSVKLLCPKCHSVQEVPHGDSLDKILQDAATEAPDIKLKATSLYYSKVWTTEDQGGRQVAVHFVKNNGILPASSECLILIEGGRLCEVSKLSSKFHSVMPVRSGPESLELLTLSAPFLIQGKVHHYGCKQCSSLKPIQNLNSRFHKGPWTPSSVAEALGVVPLQYVFVMVFTLDDGTGVLEAYLKD-SEHFFKIPASEVLTDDDLQRSLETIMDMICPPGIKVDAYPWLECLLKSYNVTIGTERRICYQIFDTTVAENVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NUX5-1", "uniprot_id": "POTE1_HUMAN", "id": "Q9NUX5-1", "name": "Protection of telomeres protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MSLVP-----ATNYIYTPLNQLKGGTIVNVYGVVKFFKPPYLSKGTDYCSVVTIVDQTNVKLTCLLFSGNYEALPIIYKNGDIVRFHRLKIQVYKKETQGITSSGFASLTFEGTLGAPIIPRTSSKYFNFTTEDHKMVEALRVWASTHMSPSWTLLKLCDVQPMQYFDLTCQLLGKAEVDGASFLLKVWDGTRTPFPSWRVLIQDLVLEGDLSHIHRLQNLTIDILVYDNHVHVARSLKVGSFLRIYSLHTKLQSMNSE--NQTMLSLEFHLHGGTSYGRGIRVLPESNSDVDQLKKDLES-ANLTANQHSDVICQSEPDD-SFPSS----GSVSLYEVERCQQLSATILTDHQYLERTPLCAILKQKAPQQYRIRAKLRSYKPRRLFQSVKLHCPKCHLLQEVPHEGDLDIIFQDGATKTPDVKLQNTSLYDSKIWTTKNQKGRKVAVHFVKNNGILPLSNECLLLIEGGTLSEICKLSNKFNSVIPVRSGHEDLELLDLSAPFLIQGTIHHYGCKQCSSLRSIQNLNSLVDKTSWIPSSVAEALGIVPLQYVFVMTFTLDDGTGVLEAYLMD-SDKFFQIPASEVLMDDDLQKSVDMIMDMFCPPGIKIDAYPWLECFIKSYNVTNGTDNQICYQIFDTTVAEDVI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "H7BX60-1", "uniprot_id": "H7BX60_MOUSE", "id": "H7BX60-1", "name": "Protection of telomeres protein 1", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MSSAP-----VAPSTYTPLNLLKEGTVVNVCGVVKFFKPPYLSKGTDYCSVVTIVDQTNVKLTCMLFSRDYDTLPSVYKVGDIVCFQGLKIQAYKNELQAISKFGFASLTFDGTLGAPIILRTLSKRFNFTAQDYSMVEALRTWASTHISASSNLVQLSDAQPMQYYDLTCQLLGKAQVDGVSFLLKVWDGTRTKIPSWRVCIQDVAFEGDLSHILQLQNLVVDIVVYDNHVQVAKSLKIGSFLRIYSLHTKLQPINSESTTS-LVRLEFHLHGGTSYGRGIRVLPESNYDVDQLKKALES-VDLEAIQTSDDTYQSDNVENCLTSSSSESDLVSLYEVERCQPLCATTLTGYHHLEKTSLCDILKQRAPRQYRIRAKLRSYKPRRLPQSVKLFCPKCHLLQEIPSEENVDKILQDATATAPDCKLQDTPLYDSEVWTTEGQGGRQVAVHFVKNDGVLPHSSECLVLIEGGRLCEISRLSSMFHSVIPVRSGPEDLELVDLAAPFLIRGKVCHYGCKQCSNLKTIQNLSIIPNKRLWIPSSVAEVLGIVPLQYVFVMTFMFDDGTGVLDVYLKD-SEKFFQIPASEVLTDDDLQRNLEQIMNVICPPGIKIDAHPWLECLIKSYNVTSGTEHQICYQIFDTMIAEDII", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F0D5-1", "uniprot_id": "E7F0D5_DANRE", "id": "E7F0D5-1", "name": "Protection of telomeres protein 1", "aln": "MPVEKVNNSSDLDTKVPSCLQLTSIGQLTLTSDPSHRCVKARVLRKGPVISCAQRDGLEMLRAEIREEDPLQSTTEHTSINVIFFDTLAKDFSQSVKQGDIVLLANFTISKSPTFLRDKLHPCQLEMDNKDACVYVCPSAIPGPSSSEAKYVYVPLNKLKSKTLVNVYGVVTFFKQPFPSKGSDYCTTLKITDQSDVKVICTIFCKKLEDHPLIFRVGDIIRLHRFKAEAFRDSITLINTFGWSTVTFNGIIDSPIVPRTSSKSFFYGEADKRRVQELRQWAANQSLCSDLNTSLSSVQPHMYFDFTCQLLAKAVMHSGCILLKVWDGTRCQLPLLQVAVPPDELEGECTLAKDKMNLTANVLVYDNHLEVARDLKPGAFLRFYNLRALLQKVPGQLPDQ-PEHLGFHLHGGTVYGRGLRSLPAETPDLLSLKSVLEKHVDLDEHEEVNDGTLLEIWY-TPPESIVLPNDENPGAEENAGP-AYTVQTCEHNTQRITLAQVKRSTPPLSCHVRARVKKYLPQQLYQCLKLFCSKCKTMKDVPDDSAVANIFLESARDNQPCDEQ----WAATSSANSREPGRTISMHVSK-DMVGKSSHMQLIFIEGMTLDEISVLSRDHKNLVPVRSENSKMTRMDLTAPFLFSGKKRYYGCKQCS-RNTFENP-VFTGVETWDEQAVAAVLGVQMMQYRFLIQFELDDVTDTIEALLWEDAERFFHISAVDASGCQDLQDRIQTIMDTIQPPESSLEERPWMDFCLSVYTVKDNDRNKVCYQITNTEIVKQ--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . : *.*** ** ::.** ***.*** *: ***:***:.:.*.* ::**: * :*. . : * ::: ***: :: :* :.::.. *. *::::**:* :. *: ** ** * : * *: ** **:.: * .*...** *:*:*****.** :.. .:********: :* :* :**: : .*. :::*****:.**:.:: *.*:*:*.*:: ** .: . * ******* ****:* ** . : .**. ** .: : . * . . *.. . * * : :: .*. : . .* . ::**:::.* *::* *.:** *.:*: ::::* : :: :.: : : : :.. : ** :::*. * : : * *::*** * *:. ** .:.::**** ..: : ::****: *. :******* ..::* * .:** .**: :** *:: * :** *..::. * : ::.**:*.* :. ::** :: **: : ** .:: **:: :. *.*. . .::**** :* :.:: ", "identical_positions": 188, "similar_positions": 212, "identity": "23.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110324-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A540-1", "uniprot_id": "AUGN_RAT", "id": "D4A540-1", "name": "Augurin", "aln": "MG-TSSARPAVLALAGLALLLLLCLGPGDVSGNKLKKMLQKREG-PVPS--KTNVAVSEHTAKEFLGGLKRAKRQLWDRTRPEVQQWYQQFLYMGFDEAKFEDDVNYWLNRNQNGHDYYGDYYQRHYDEDAAIGPRSREGFRHGASVNYDDY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99LS0-1", "uniprot_id": "AUGN_MOUSE", "id": "Q99LS0-1", "name": "Augurin", "aln": "MS-TSSARPAVLALAGLALLLLLCLGPDGISGNKLKKMLQKREG-PVPS--KTNVAVAENTAKEFLGGLKRAKRQLWDRTRPEVQQWYQQFLYMGFDEAKFEDDVNYWLNRNRNGHDYYGDYYQRHYDEDAAIGPHSRESFRHGASVNYNDY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H1Z8-1", "uniprot_id": "AUGN_HUMAN", "id": "Q9H1Z8-1", "name": "Augurin", "aln": "MA-ASPARPAVLALTGLALLLLLCWGPGGISGNKLKLMLQKREA-PVPT--KTKVAVDENKAKEFLGSLKRQKRQLWDRTRPEVQQWYQQFLYMGFDEAKFEDDITYWLNRDRNGHEYYGDYYQRHYDEDSAIGPRSPYGFRHGASVNYDDY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CAX4-1", "uniprot_id": "AUGNB_DANRE", "id": "P0CAX4-1", "name": "Augurin-B", "aln": "MSLHSLCVPTILLIS----VLSICLSSGGSSDSKLHRILIKRDAKEIESRPKAYISVQQSKAKEFLSGLHRTKRNVWDRSRPDVQQWIQQFMYMGYDEARLETDLSYWMDQARSNDQGR----QHHHDENAPMSQQDPRYNRHGANVNYDYY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. * . *::* :: :* :* .... *..**: :* **:. : : *: ::* : .*****..*:* **::***:**:**** ***:***:***::* *:.**::: :...: *:*:**::.:. :. ****.***: *", "identical_positions": 57, "similar_positions": 57, "identity": "37.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110325-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D0Y8-1", "uniprot_id": "RM52_MOUSE", "id": "Q9D0Y8-1", "name": "Large ribosomal subunit protein mL52", "aln": "-MAALGTWLSS-----VRRLHCSVVARAGGQWRLQQGLAANPSGYGPLTELPDWSFADGRPAPPMKGQLRRKAQREKLARRVVLLTQEMDAGIQAWKLRQ-QKLQEE-RKKEHDLKPKGTLLRSPLPNQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86TS9-1", "uniprot_id": "RM52_HUMAN", "id": "Q86TS9-1", "name": "Large ribosomal subunit protein mL52", "aln": "-MAALGTVLFTG----VRRLHCSVAAWAGGQWRLQQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAERETFARRVVLLSQEMDAGLQAWQLRQ-QKLQEEQRKQENALKPKGASLKSPLPSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F658-1", "uniprot_id": "E7F658_DANRE", "id": "E7F658-1", "name": "Large ribosomal subunit protein mL52", "aln": "MAAALRTVGAAVSRQSVRTFSSTCVTHAGIKWRLENGLPRGGSEYGPLTDLPDWSFADGRPAPLLKGQIRRQKQREEFARRAVYLNAEMDEGMKQWHESEKAKKQKEEDVKSLLLKPKGNLFKQKKK--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** * : ** : .: .: ** :***::**. . * *****:*****:******* :***:**: :** :***.* *. *** *:: *: : * *:* :. ***** ::. ", "identical_positions": 56, "similar_positions": 30, "identity": "43.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110328-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P97738-1", "uniprot_id": "NPTX2_RAT", "id": "P97738-1", "name": "Neuronal pentraxin-2", "aln": "----------MLALLTAGVALA--VAAGQAQDNPIPGSRFVCTALPPEAARAGCPLPAMPMQGGALSPEEELRAAVLHWRETVVQ---------------------------QKETLGAQREAIRELTSKLARCEGLAGGKARGTGATGKDTMGDLPRDPGHVVEQLS-----RSLQTLKDRLESLELQ-LHTNASNAGLP--------------------------------SDFREVLQRR------LGELERQLLRKVAELEDEKSLLHNET------------------SAHRQKTENTLNALLQRVTELERGNSAFKSPDAFKVSLPLRTNYLYGKIKKTLPELYAFTICLWLRSSASPGIGTPFSYAVPGQANEIVLIEWGNNPIELLINDKVAQLP----LFVSDGKWHHICITWTTRDGMWEAFQDGEKLGTGENLAPWHPIKPGGVLILGQE--------QDTVGG------RFDATQAFVGELSQFNIWDRVLRAQEIINIAN--CSTNMPGNIIPWVDNNVDVFGGASKWPVETCEERLLDL------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70340-1", "uniprot_id": "NPTX2_MOUSE", "id": "O70340-1", "name": "Neuronal pentraxin-2", "aln": "----------MLALLTVGVALA--VAAGRAQDSPIPGSRFVCTALPPEAARAGCPLPAMPMQGGALSPEEELRAAVLQLRETVVQ---------------------------QKETLGAQREAIRELTGKLARCEGLAGGKARGT---GKDTMGDLPRDPGHVVEQLS-----RSLQTLKDRLESLELQ-LRTNVSNAGLP--------------------------------SDFREVLQRR------LGELERQLLRKVAELEDEKSLLHNET------------------SAHRQKTESTLNALLQRVTELERGNSAFKSPDAFKVSLPLRTNYLYGKIKKTLPELYAFTICLWLRSSASPGIGTPFSYAVPGQANEIVLIEWGNNPIELLINDKVAQLP----LFVSDGKWHHICITWTTRDGMWEAFQDGEKLGTGENLAPWHPIKPGGVLILGQE--------QDTVGG------RFDATQAFVGELSQFNIWDRVLRAQEIINIAN--CSTNMPGNIIPWVDNNVDVFGGASKWPVETCEERLLDL------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47972-1", "uniprot_id": "NPTX2_HUMAN", "id": "P47972-1", "name": "Neuronal pentraxin-2", "aln": "----------MLALLAASVALA--VAAG-AQDSPAPGSRFVCTALPPEAVHAGCPLPAMPMQGGAQSPEEELRAAVLQLRETVVQ---------------------------QKETLGAQREAIRELTGKLARCEGLAGGKARGAGATGKDTMGDLPRDPGHVVEQLS-----RSLQTLKDRLESLEHQ-LRANVSNAGLP--------------------------------GDFREVLQQR------LGELERQLLRKVAELEDEKSLLHNET------------------SAHRQKTESTLNALLQRVTELERGNSAFKSPDAFKVSLPLRTNYLYGKIKKTLPELYAFTICLWLRSSASPGIGTPFSYAVPGQANEIVLIEWGNNPIELLINDKVAQLP----LFVSDGKWHHICVTWTTRDGMWEAFQDGEKLGTGENLAPWHPIKPGGVLILGQE--------QDTVGG------RFDATQAFVGELSQFNIWDRVLRAQEIVNIAN--CSTNMPGNIIPWVDNNVDVFGGASKWPVETCEERLLDL------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U432-1", "uniprot_id": "A0AB32U432_DANRE", "id": "A0AB32U432-1", "name": "", "aln": "----------MLHLIAGLICVYGLTCVKVVYGQTEKGERFLCTAVPIDQDTS-CPVPVP----SASLQEEELRNTVMQLRETILQ---------------------------QKETIVNQLGTIKELTSKLSRCESESEIFRKMN----KDTMDDVPKDPNDTIDVLG-----KTMQGLKDRLENLEQQQMRANASGASFP--------------------------------NELRNLLQHR------LEDLENQLLKKVNELEEEKSQLYNET------------------VAHRQRTDNTLNSLMNRISELEKGGAGFKSPENFKISLPLRTNYLFGQVKKSLPEMYAFTICMWLKSGSSPGIGTPFSYGVPGQANEIVLIEWGHNPIELLINDKVAQLP----LSLSDGRWHHVCITWTTRDGLWEAYQDGQRLGSGENLAPWHPIKPGGVLILGQEQACRLWPQQDVVGG------RFDATQAFVGELSHFNIWDRVLRSTDIITMAN--CSSYMPGNVVSWTDSNIEVFGGASKGPLELCEDRLFDN------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3N9-1", "uniprot_id": "Q9V3N9_DROME", "id": "Q9V3N9-1", "name": "", "aln": "MAQRLHLALVGVVLLNATASFAWKPIVGGGSGISGGTAAYSLKQSHPGAASSSHEISTSFSQFGGDKETTEVEDELLLGRAAIVNGVDSSAAVSHPISFADHLEDQYESYSIEDEAPKEPLAFPRSPVYGSDRCSVKKFAFNQDGEVEYGNPMPELDQFTICFWMRFTNHSGDHVLLTYEAGKEPREVQIWVANAQNSSFLSMAIKGQQMYRLNYPLKMRQWHHMCSSWNGKTGEWQAWLKAERIGRGFHNSLVGHKIPANGKLRSGGSSVTGEVSHGLHFEMTLVQVYRVALSAGKAHRDHKHHHVHHFDHEGQEVSSTTRAPPSINRPQPMHTLLASGQIPTRVRINLANPPPTASGAPAPGAAGAPTDSAQQAITINTNFVNGQINAGSRLVAQQLLGLSPPSGLQPSGGGKRFQMLSNSANVQFIDETETHIQFKR--NTDATKKVQKRGLVLLDDGS-----VVDDGVGSGTDGSLIYNGLADFGGQQFKQDLTLKMSLEEEISTHDREPAEEEVRAVMAICSSCHTEPFQGAIVFSWKDVREHMNNALKGLSVGPCGNF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: .. . . . : . : :.. .. *:. :: * :::: :.*: :. . **. : :.* :: : . : : : : * * * :*...:.: .: : *: . .* : : :*.. * : .*. * : : : . : : : * :. .: ::* :: . *::* *:: . : * . : :. . *:* . . . : : ::: *. . *: ::: *. * *.* :. :: ::. : : : :: * . : :: *:::*.: :* **. ::. * *: : :: :: :* . . .. : . : . : : * ** . : .::: : ", "identical_positions": 43, "similar_positions": 156, "identity": "7.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110331-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JWG1-1", "uniprot_id": "A0A0G2JWG1_RAT", "id": "A0A0G2JWG1-1", "name": "Alpha-mannosidase", "aln": "-MKLKKQVTVCGAAIFCVAVFSLYLMLDRVQHDPARHQNGGNFPRSQISVLQNRIEQLEQLLEENHEIISHIKDSVLELTAN-AEGPPALLPYHTANGSWAVLPEPRPSFFSVSPEDCQFALGGRGQKPELQMLTVSEDLPFDNVEGGVWRQGFDISYSPNDWDAED-LQVFVVPHSHNDPGWIKTFDKYYTEQTQHILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNISAQKRAAVRRLVGNGQLEIATGGWVMPDEANSHYFALVDQLIEGHQWLERNLGATPRSGWAVDPFGHSSTMPYLLRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQTWDSDSSTDIFCHMMPFYSYDVPHTCGPDPKICCQFDFKRLPGGRINCPWKVPPRAITEANVADRAALLLDQYRKKSRLFRSSVLLVPLGDDFRYDKPQEWDAQFFNYQRLFDFLNSKPEFHVQAQFGTLSEYFDALYKRTGVEPGARPPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKSLDRVLETHLRGAEVLYSLALAHARRSGLTGQYPLSDYAVLTEARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVSLKQVIINAAHYLVLGDKETYSFDPRAPFLQMDDSRVSHDALP-ERTVIRLDS---SPRFVVVFNPLEQERLSVVSLLVNSPRVRVLSEEGQPLSVQISVQWSSATNMVP---------DVYQVSVPVRLPALGLGVLQLQPDLDGPYTLQSSVHVYLNGVKLSVSRQTTFPLRVVDSGTSDFAISNRYMQVWFSGLTGLLKSVRRVDEEQEQQVDMKLFVYGTRTSKDKSGAYLFLPDNEAKPYVPKKPPVLRVTEGPFFSEVAAYYEHFHQVIRLYNLPGVEGLSLDVSFQVDIRDYVNKELALRIHTDIDSQGTFFTDLNGFQVQPRKYLKKLPLQANFYPMPVMAYIQDSQRRLTLHTAQALGVSSLGNGQLEVILDRRLMQDDNRGLGQGLKDNKITCNHFRLLLERRTLMSPEPGFFSKLAAMFRGLIFSSNTIRNSKVQQERSTSYPSLLSHMTSMYLNTPPLVLPVAKRESTSPTLHSFHPLASPLPCDFHLLNLRMLP-AED-TLPAADAALILHRKG-FDCGLEAKNLGFNCTTSQGKLALGSLFHGLDVLFLQPTSLTLLYPLASPSNSTDISLEPMEISTFRLRLG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BRK9-1", "uniprot_id": "MA2A2_MOUSE", "id": "Q8BRK9-1", "name": "Alpha-mannosidase 2x", "aln": "-MKLKKQVTVCGAAIFCVAVFSLYLMLDRVQHDPARHQNGGNFPRSQISVLQNRIEQLEQLLEENHDIISRIKDSVLELTAN-AEGPPALLPYHTANGSWAVLPEPRPSFFSVSPQDCQFALGGRGQKPELQMLTVSEDLPFDNVEGGVWRQGFDISYSPNDWDTED-LQVFVVPHSHNDPGWIKTFDKYYTEQTQHILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNISAQKRAAVRRLVGNGQLEIATGGWVMPDEANSHYFALVDQLIEGHQWLERNLGATPRSGWAVDPFGHSSTMPYLLRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQMWDSDSSTDIFCHMMPFYSYDVPHTCGPDPKICCQFDFKRLPGGRINCPWKVPPRAITEANVADRAALLLDQYRKKSRLFRSNVLLVPLGDDFRYDKPQEWDAQFFNYQRLFDFLNSKPEFHVQAQFGTLSEYFDALYKRTGVEPGARPPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKSLDRVLEAHLRGAEILYSLALAHARRSGLAGQYPLSDFALLTEARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVSLKQVIINAAHYLVLGDQETYSFDPGTPFLQMDDSRVSHDALP-ERTVIRLDS---SPRFVVVFNPLEQERLSVVSLLVNSPRVRVLSEEGQPLSVQISVHWSSATDMVP---------DVYQVSVPVRLPGLGLGVLQLQPDLDGPYTLQSSVRVYLNGVKLSVSRQSAFPVRVVDSGASDFAISNRYMQVWFSGLTGLLKSIRRVDEEQEQQMELEFLVYGTRTSKDKSGAYLFLPDSEAKPYVPKKPPVLRVTEGPFFSEVAVYYEHFHQVIRLYNLPGVEGLSLDMSFQVDIRDYVNKELALRIHTDIDSQGTFFTDLNGFQIQPRQYLKKLPLQANFYPMPVMAYIQDSQRRLTLHTAQALGVSSLGNGQLEVILDRRLMQDDNRGLGQGLKDNKITCNRFRLLLERRTTMSP-----------------------EVHQEQERSTSYPSLLSHLTSMYLSTPPLVLPVAKRQGTSPALRSFHPLASPLPCDFHLLNLRMLP-AED-TLPATDSALILHRKG-FDCGLEAKNLGFNCTTSQGKLALGSLFHGLDVTFLQPTSLTLLYPLASPSNSTDISLEPMEISTFRLRLG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49641-3", "uniprot_id": "MA2A2_HUMAN", "id": "P49641-3", "name": "Alpha-mannosidase 2x", "aln": "-MKLKKQVTVCGAAIFCVAVFSLYLMLDRVQHDPTRHQNGGNFPRSQISVLQNRIEQLEQLLEENHEIISHIKDSVLELTAN-AEGPPAMLPYYTVNGSWVVPPEPRPSFFSISPQDCQFALGGRGQKPELQMLTVSEELPFDNVDGGVWRQGFDISYDPHDWDAED-LQVFVVPHSHNDPGWIKTFDKYYTEQTQHILNSMVSKLQEDPRRRFLWAEVSFFAKWWDNINVQKRAAVRRLVGNGQLEIATGGWVMPDEANSHYFALIDQLIEGHQWLERNLGATPRSGWAVDPFGYSSTMPYLLRRANLTSMLIQRVHYAIKKHFAATHSLEFMWRQTWDSDSSTDIFCHMMPFYSYDVPHTCGPDPKICCQFDFKRLPGGRINCPWKVPPRAITEANVAERAALLLDQYRKKSQLFRSNVLLVPLGDDFRYDKPQEWDAQFFNYQRLFDFFNSRPNLHVQAQFGTLSDYFDALYKRTGVEPGARPPGFPVLSGDFFSYADREDHYWTGYYTSRPFYKSLDRVLEAHLRGAEVLYSLAAAHARRSGLAGRYPLSDFTLLTEARRTLGLFQHHDAITGTAKEAVVVDYGVRLLRSLVNLKQVIIHAAHYLVLGDKETYHFDPEAPFLQVDDTRLSHDALP-ERTVIQLDS---SPRFVVLFNPLEQERFSMVSLLVNSPRVRVLSEEGQPLAVQISAHWSSATEAVP---------DVYQVSVPVRLPALGLGVLQLQLGLDGHRTLPSSVRIYLHGRQLSVSRHEAFPLRVIDSGTSDFALSNRYMQVWFSGLTGLLKSIRRVDEEHEQQVDMQVLVYGTRTSKDKSGAYLFLPDGEAKPYVPKEPPVLRVTEGPFFSEVVAYYEHIHQAVRLYNLPGVEGLSLDISSLVDIRDYVNKELALHIHTDIDSQGIFFTDLNGFQVQPRRYLKKLPLQANFYPMPVMAYIQDAQKRLTLHTAQALGVSSLKDGQLEVILDRRLMQDDNRGLGQGLKDNKRTCNRFRLLLERRTVGSE--------------------------VQDSHSTSYPSLLSHLTSMYLNAPALALPVARMQLPGPGLRSFHPLASSLPCDFHLLNLRTLQ-AEEDTLPSAETALILHRKG-FDCGLEAKNLGFNCTTSQGKVALGSLFHGLDVVFLQPTSLTLLYPLASPSNSTDVYLEPMEIATFRLRLG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AWC8-1", "uniprot_id": "A0A8M3AWC8_DANRE", "id": "A0A8M3AWC8-1", "name": "Alpha-mannosidase", "aln": "-MKLKKQVTVCGGAIFCVAVFSLYLMLDRVQHDPARRQNGGNFPRSQISVLQNRIEQLEQLLEENHQIISHIKDSVLELTDTGAISPSGHLPFRSANGSWVLPFDGRPTFLSVKPLDCQFALGRRSQ-TDLQMLDVYSLLNFDNVDGGVWKQGFEITYEPNEWDDEP-LQVFVVPHSHNDPGWIKTFDKYYNDQTQHILNNMVTKMAEDPRRKFIWSEISYFAKWWESADVHKQEVMRKLILSGQLEMVTGGWVMTDEANAHYFAMIDQLIEGHQWLERNLGVTPRSGWAVDPFGHSATMPYLLKRANISSMLIQRVHYSIKKHFAATRSLEFMWRQAWDIESSTDMFCHMMPFYSYDVPHTCGPDPKICCQFDFKRLPGSRVNCPWKVPPRAINDANVAERAGVLLDQYRKKSKLFRSKVLLVPLGDDFRYDKALEWDQQYLNYQKLFDYMNSHPEMHVKAQFATLSDYFDAVYKANGVTSGARPPDYPVLSGDFFAYADREDHYWSGYYTSRPFYKNLDRILESHLRGAEILYSLAVAHARHAGVEGRYPVSDYSLLTDARRNIGLFQHHDAITGTAKEAVVIDYGNRLLRSLVGLKRVIINAAHFLIIKNKDIYRFYQTEPFLETDDRRATQDSLP-QRTLIELES---SPRYLVLFNPVEQERLCLVTVLVNSARVRVLTEDGQTLPVQLSAQWMSATEMSG---------EVYQASFMARLPALGLAVFHLYDSADSPMTLRSETLLRVPGRGQSIRGLDPLPVRSQTVDGQPFYIQTQSLTLGFSGATGLLESIRRKDDPQEVRVQIQFLTYGTRPSKDKSGAYLFLPDGNAKPYSQRETPIVRVVEGPLFAEVVAHYQHFQQTVRIHNVPGVDGLSLDITTMVDIRDQNNKELAMRFVTDIQSGDTFYTDLNGFQIQPRRYFQKLPLQANFYPMPSTAYIQDSQYRLTLHTAQALGVTSLASGQLEVILDRRLMQDDNRGLGQGLKDNKRTANRFRLLLERRSNSAKPAGSYAKVTNMLNKIIAGILGDGQEEPVDSRPVSFPSLLSHMTSTILNHEVLALPVLPRKHGVPPMRTFAPLAGTLPCDFHLLNLRSIQSPQDAHSPSPYMALLLHRLG-LDCGLEPQNPGFNCTTTQGQLSVSGLFRGLDLQLLQPMSLSLMHSQPPLSNDSSVSLDPMEISAYKLKLC-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24451-1", "uniprot_id": "MAN2_DROME", "id": "Q24451-1", "name": "Alpha-mannosidase 2", "aln": "MLRIRRRFALVICSGCLLVFLSLYIILN--FAAPAATQIKPNYEN-----IENKLHELENGLQEHGEEMRNLRARLAETSNR---DDPIRPPLKVAR--------------SPRPGQCQDVVQDVPN-VDVQMLELYDRMSFKDIDGGVWKQGWNIKYDPLKYNAHHKLKVFVVPHSHNDPGWIQTFEEYYQHDTKHILSNALRHLHDNPEMKFIWAEISYFARFYHDLGENKKLQMKSIVKNGQLEFVTGGWVMPDEANSHWRNVLLQLTEGQTWLKQFMNVTPTASWAIDPFGHSPTMPYILQKSGFKNMLIQRTHYSVKKELAQQRQLEFLWRQIWDNKGDTALFTHMMPFYSYDIPHTCGPDPKVCCQFDFKRMGSFGLSCPWKVPPRTISDQNVAARSDLLVDQWKKKAELYRTNVLLIPLGDDFRFKQNTEWDVQRVNYERLFEHINSQAHFNVQAQFGTLQEYFDAVHQAERAG----QAEFPTLSGDFFTYADRSDNYWSGYYTSRPYHKRMDRVLMHYVRAAEMLSAWHSWDG-MARIEER--------LEQARRELSLFQHHDGITGTAKTHVVVDYEQRMQEALKACQMVMQQSVYRLLTKP-SIYSPDFSFSYFTLDDSRWPGSGVEDSRTTIILGEDILPSKHVVMHNTLPHWREQLVDFYVSSPFVSVTDLANNPVEAQVSPVWSWHHDTLTKTIHPQGSTTKYRIIFKARVPPMGLATYVLTISDSKPEHTSYASNLLLRKNPTSLP-LGQYPEDVKFGDPREISLRVGNGPTLAFSEQGLLKSIQLTQDSPHVPVHFKFLKYGVRSHGDRSGAYLFLPNGPASP-VELGQPVVLVTKGKLESSVSVGLPSVVHQTIMR------GGAPEIRNLVDIGSLDNTEIVMRLETHIDSGDIFYTDLNGLQFIKRRRLDKLPLQANYYPIPSGMFIEDANTRLTLLTGQPLGGSSLASGELEIMQDRRLASDDERGLGQGVLDNKPVLHIYRLVLEKVNNCVR--------------------------PSELHPAGYLTSAAHKASQSLLDPLDKFIFAENEWIG----AQGQFGGDHPSAREDLDVSVMRRLTKSSAKTQRVGYVLHRTNLMQCGTPEEHT--------QKLDVCHLLP--NVARCERTTLTFLQNLEHLDGMVAPEVCPMETAAYVSSHSS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::::::.:: : :..:***::*: *: * *: . ::*::.:**: *:*: : : .:: : * : . . * .. * * :** .: : ::*** : . : *.:::****:**::*.*.* .:: . *:**************:**::** .:*:***.. : :: ::*. :*:*:*:*:**:::.. . :*: :: :: .****:.******.****:*: :: ** **: **:: :..** :.**:****:*.****:*:::.:..*****.**::**.:* :.***:*** ** ...* :* *********:*********:********: . :.********:*.: *** *: :*:**::**:.*:*:.***:*******:.: *** * .**::**:.:**:..::*:***.**.:****::: . . :*.******:****.*:**:*******::* :**:* ::*.**:* : .. : : : * :*** :.******.****** **:** *: .:* : *: ::.: *: . * .:: ** * . ..: .** * * . ..:.:*:.*.: : * :* . *.*. * * .:.: .*:* * : *: . .*:* :**.. * . . : : *: * . : : . ***:*:: :: . :.::.: **.*. *:********:. *.* *:: *.:* : :.* . . : : * : :: *** . *.*:.::: *.*:* . *:*****:*. *: :.*******:**:* :*:*:: **** *.*.** :** .*:**:: **** .**:******: *** . : :**:**: . : :...: : :* :* * : . : : :.. *. . *:: : . : . :*** . ::** :: :: : *: :: : :*::: .. : *** ::: ", "identical_positions": 371, "similar_positions": 375, "identity": "31.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110401-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VGV6-1", "uniprot_id": "Q9VGV6_DROME", "id": "Q9VGV6-1", "name": "Thiamine transporter 1", "aln": "------------------------------------------------MESWLKISCLLCIFGFLRELRPSEPYHAEILMGEWYHVTQDEVNRSVYPVGTYSYLALLIFVFLITDLLRYKPVIIANATTGICIWGTLIWTTTLSGLQAVEVFYGFYQAGEVAYYSYIYAKVDKQYYPRVTSHTRAAMFVGKLVAGILAQMVIGMRWMNYKQLFYITVTSQVAALLWAFFLPKVEKSLYFHN-------RSEAIEGGTKSDGGNLEKGSEQPSNEEASQEKKIPALQLLWSHFRSAYTNPLVIQWSLWYAISLAGFLQITTYMQVVWKSFENEPT--IAWNGAVDVALTLLSAVFALLAGYFHAGRLNTRSSLLSMALLSVLEGGCVLLSCWTDD---IYLSYLGYVLYGGLFAFTITVASSELASSLEEDSFALVFGFNTFVGLLLQCILTFVVVSEKANLNLNVFQQFSVYAFYFIVIGIVYSIAVILQYIWSISKKPKAIQEAN--------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VGV5-1", "uniprot_id": "Q9VGV5_DROME", "id": "Q9VGV5-1", "name": "Thiamine transporter 1", "aln": "------------------------------------------------MKEWLKISCLLCVFGCIREIRPSEPYVTEYLLGPWRNITEQQLTHDVYPVGTYSYLVQLVFVFLITDFLRYKPLIITIGAAGVIIWSMLIWTTSLLSLQILEFFFGTYMAAEVAYYTYIYAKVDKKYYARVTSHTRAAMFAGKLVSGITSQLMLNLELMNYKELNYITLGTQIIAMLWAFGLPRVDRSLYFHR-------EQLSITEPQTQLPG-VGNLAEMDQQQENTQ-KQPGALSLLWLHFRNAYTNPRVVQWSLWYAIGLAGYLQVTYYVQVLWKVIEPEPV--IAWNGAVDAVLTALAALSALAAGYLHTGRLRPRASLLILGILSAVEGGCVLICCWTQD---IYWSYAGFVLFGALYGFTITVASAEVARNLEEESFGLVFGVNTFVALIFQSLLTIIFVTDTG-FELDPVGQYTAYAFYFIGVGVLYLISVLIEYLMCRNNDVEKLENSLD-------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VK64-1", "uniprot_id": "Q9VK64_DROME", "id": "Q9VK64-1", "name": "Thiamine transporter 1", "aln": "------------------------------------------------MKSWLKISLLLCTFGFFREFRPSEPYVTEYLASDYGNLTTDQIYQDVYPFGTYSVLAQLVIVFLITDLVRYKPVIVLSALAGITLFSMLIWTETVGMLQVAQVFFGTFTAAEVAYYTYMYAKVNKEQYQVVTGHTRAAILSGKFLGGLFAQILVSTDSMDYRQLHYLSLATQLISLAVSLFLPSVPRSLYFYA-------GSEKIT---------IADGEETSPKFSFAN-----ACRLLWYHLVSSYSNPVVLQWSIWWALATCGQVQVISYIQFLWKEVAPNKL--SVYNGGVEAVATLLGAIGAILAGLLNSNKRRG-SYMMGISICAAALGALLIYAAKTQL---IWVAYVNYVLFCTVFFFIITVAGAVVAENLVEDSFGLIFGINTLVGLILQTILTVAVVERVG-FALEPRDQYVVYGSYFVVLGGISIIGSICVKLFCRTNK-SSVENVVSLT-----------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q62866-1", "uniprot_id": "S19A1_RAT", "id": "Q62866-1", "name": "Reduced folate transporter", "aln": "MVPT------------------GQVAEKQACE----EPRQDRE-----LKSWRWLVFYLCFFGFMAQLRPGESFITPYLL--ERNFTKEQVTNEIIPMLPYSHLAVLVPIFLLTDYLRYKPVLVLQCLSFVCVWLLLLLGTSVVHMQLMEVFYSITMAARIAYSSYIFSLVQPSRYQRMASYSRAAVLLGVFISSVLGQVLVTLGGISTYMLNCISLGFILFSLSLSLFLKRPKRSLFFNRSALV--QGALPC-ELDQMHPGP--GRPEPRKLERMLGTCRDSFLVRMLSELVKNVRQPQLRLWCLWWVFNSAGYYLITYYVHVLWKITDSRLN----YNGAVDAASTLLSAITAFTAGFVNIR--WALWSKLVIASVIAIQAGLVFCMFQIPD---IWVCYVTFVLFRGAYQFLVPIATFQIASSLSKELCALVFGINTFLATALKTSITLVVSDKRG-LGLQVHQQFRIYFMYFLTLSIICLAWAGLDGLRYYRRGRHQPLAQAQAL-SPLED-SVQAISLQDGDLRRPQPS-APQLLPEDGS-------VEDGRAD-LRVEAKA-------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P41438-1", "uniprot_id": "S19A1_MOUSE", "id": "P41438-1", "name": "Reduced folate transporter", "aln": "MVPT------------------GQVAEKQAYE----EPRQDHE-----LKSWRCLVFYLCFFGFMAQLRPGESFITPFLL--ERKFTKEQVTNEIIPMLPYSHLAVLVPVFLLTDYLRYKPVLVLQCLSFVCVWLLLLLGTSVVHMQLMEVFYSVTMAARIAYSSYIFSLVHPSRYQRMASYSRAAVLLGVFISSVLGQALVTVGHISTYTLNCVSLGFILFSLVLSLFLKRPKRSLFFNRSTLA--RGALPC-ELDQMHPGP--DRPETRKLDRMLGTCRDSFLVRMLSELVENARQPQLRLWCLWWVFNSSGYYLITYYVHVLWRSTDSSLS----YNGAVDAASTLLSAITSFSAGFLSIR--WTLWSKLVIAGVIAIQASLVFCMFQIRD---IWVCYVTFVLFRGAYQFLVPIATFQIASSLSKELCALVFGINTFLATALKTCITLVVSDKRG-LGLQVRDQFRIYFIYFLMLSITCFAWAGLDGLRYCQRGRHQPLAQAQELRSPLET-SVQAISLQDGDLRGPQPS-APQLLSEDG--------MEDDRGD-LRVEAKA-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P41440-1", "uniprot_id": "S19A1_HUMAN", "id": "P41440-1", "name": "Reduced folate transporter", "aln": "MVPS------------------SPAVEKQVPV----EPGPDPE-----LRSWRHLVCYLCFYGFMAQIRPGESFITPYLLGPDKNFTREQVTNEITPVLSYSYLAVLVPVFLLTDYLRYTPVLLLQGLSFVSVWLLLLLGHSVAHMQLMELFYSVTMAARIAYSSYIFSLVRPARYQRVAGYSRAAVLLGVFTSSVLGQLLVTVGRVSFSTLNYISLAFLTFSVVLALFLKRPKRSLFFNRDDRG--RCETSASELERMNPGP--GGKLGHALR---VACGDSVLARMLRELGDSLRRPQLRLWSLWWVFNSAGYYLVVYYVHILWNEVDPTTNSARVYNGAADAASTLLGAITSFAAGFVKIR--WARWSKLLIAGVTATQAGLVFLLAHTRHPSSIWLCYAAFVLFRGSYQFLVPIATFQIASSLSKELCALVFGVNTFFATIVKTIITFIVSDVRG-LGLPVRKQFQLYSVYFLILSIIYFLGAMLDGLRHCQRGHHPRQPPAQGLRSAAEEKAAQALSVQDKGLGGLQPAQSPPLSPEDSLGAVGPASLEQRQSDPYLAQAPAPQAAEFLSPVTTPSPCTLCSAQASGPEAADETCPQLAVHPPGVSKLGLQCLPSDGVQNVNQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F2A7-1", "uniprot_id": "E7F2A7_DANRE", "id": "E7F2A7-1", "name": "", "aln": "MVEESTSNERTEDVKENMTDENGQPVENVAPESVILETKEDLEAQTQKTRTWMWSVVYLCFYGFMVQLKPGEPFITPYLLSTEKNFTREQVTNEINPVLSYSYMVVLVPVFLLTDYLRYKPVLVLQSLSHVSIWLLLLLGNSLLEMQFMEFFYGITMAARVAYSSYIFSLVPATVYQRVASYSRSSVLMGVFTSSVLGQMCVSLGGISYTMLSAVSLGFVSFGLLLSFCLPWPKRSMFFNKARMEEERKEAAKSELAKMKPEEKDGIVEGMDTNRSSPSWTNSVFVGMLKELKHVVKVPSLRLWSLWWVFNSTGYYLVLFYVHILWNKVYPATENKNVYNGAVEAASTLLGAITSFAAGYVKIR--WNLWSELVIGLITAAQAALLLLMGMTED---IWVCYVAYALFKGFYQFLVPIAIFQIASSLTKELCALVFGVNTFLGTILKAIITIIVADKRG-LALSVHSQFFVYFFYFTLLTVIYLGCSAFIITCHYRNQRAGAESTEEAVSTELSPIATAASESTTVHNGTSIKT----------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * ** :* : :::*.*.: : * :.* ::: ..: *. .** :. *: :**:** :**.*::: : : :: *: :: :* :.*:. *..:** :*::: * * ::.::*:::: * : ..: .* : :. * ::: .: :: * :*::* : .: * : *.:*:.: * : *::.:*. :**..:.. * *.*: :: ** . : :. . .. :: *: .* :.*: : * :.:* :* .* :: .*:**.**:.. .: :*. . . : * *: * ** : . ", "identical_positions": 66, "similar_positions": 139, "identity": "10.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110401-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIQ4-1", "uniprot_id": "MGRN1_RAT", "id": "Q5XIQ4-1", "name": "E3 ubiquitin-protein ligase MGRN1", "aln": "MGSILSRRIAGVEDIDIQANSAYRYPPKSAGNYFASHFFMGGEKFDTPHPEGYLFGENMDLNFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVR-------------------------YKDDTDSPTEDGE-------------------KPRVLYSLEFTFDADARVAITIYCQAVEEFVNGMTVYSCKNPSLQSETVHYKRGVSQQFSLPSFKIDFSEWKDDELNFDLDRGVFPVVIQAVVDEGDVVEVTGHAHVLLAAFEKHVD-GSFSVKPLKQKQIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSSECVVCLSDLRDTLILPCRHLCLCTSCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPISFSPVLAQSVDHDEHS----------------------NSDSVPPGYEPISLLEALNG-------------------------------LRAVSPAIPSAPLYEEITYSGISDGLSQASCPLA---------GLDRIIENGIQKGKTQSKSPDSTLRSPSSPIHEED--------------------------------EEKLS---------EDPEAPLPPSGVELVLQESSSP-ESFGTEEVGEPS-LKQGSRVP---------------SIDDVLQDG---SPQHHGCSQPV--PPADIYLP-------ALGPESCSVGIEE---------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D074-1", "uniprot_id": "MGRN1_MOUSE", "id": "Q9D074-1", "name": "E3 ubiquitin-protein ligase MGRN1", "aln": "MGSILSRRIAGVEDIDIQANSAYRYPPK-SGNYFASHFFMGGEKFDTPHPEGYLFGENMDLNFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVR-------------------------YKEDADSPTEDGE-------------------KPRVLYSLEFTFDADARVAITIYCQAVEELVNGVAVYSCKNPSLQSETVHYKRGVSQQFSLPSFKIDFSEWKDDELNFDLDRGVFPVVIQAVVDEGDVVEVTGHAHVLLAAFEKHVD-GSFSVKPLKQKQIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSSECVVCLSDLRDTLILPCRHLCLCTSCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPISFSPVLAQSVDHDEHS----------------------SSDSIPPGYEPISLLEALNG-------------------------------LRAVSPAIPSAPLYEEITYSGISDGLSQASCPLA---------GLDRIMESGLQKGKTQSKSPDSTLRSPSFPIHEED--------------------------------EEKLS---------EDSDAPLPPSGVELVLRESSSP-ESFGTEEGDEPS-LKQGSRVP---------------SIDDVLQDG---SPQHHGCSQPV--PPADIYLP-------ALGPESCSVGIEE---------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60291-1", "uniprot_id": "MGRN1_HUMAN", "id": "O60291-1", "name": "E3 ubiquitin-protein ligase MGRN1", "aln": "MGSILSRRIAGVEDIDIQANSAYRYPPK-SGNYFASHFFMGGEKFDTPHPEGYLFGENMDLNFLGSRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVR-------------------------YKDDADSPTEDGD-------------------KPRVLYSLEFTFDADARVAITIYCQASEEFLNGRAVYSPKSPSLQSETVHYKRGVSQQFSLPSFKIDFSEWKDDELNFDLDRGVFPVVIQAVVDEGDVVEVTGHAHVLLAAFEKHMD-GSFSVKPLKQKQIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLCTSCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSLEHDEHSCPFKKSKPHPASLASKKPKRETNSDSVPPGYEPISLLEALNG-------------------------------LRAVSPAIPSAPLYEEITYSGISDGLSQASCPLA---------AIDHILDSSRQKGRPQSKAPDSTLRSPSSPIHEED--------------------------------EEKLS---------EDVDAPPPLGGAELALRESSSP-ESFITEEVDESSSPQQGTRAA---------------SIENVLQDS---SPEHCGRG-----PPADIYLP-------ALGPDSCSVGIDE---------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0R0J5-1", "uniprot_id": "B0R0J5_DANRE", "id": "B0R0J5-1", "name": "E3 ubiquitin-protein ligase", "aln": "MGSILSRRIAGVEDIDIQANSAYRYPPK-SGNYFASHFFMGGEKFDTPHPEGYLFGENMDLNFLGNRPVQFPYVTPAPHEPVKTLRSLVNIRKDSLRLVR-------------------------YKDDADTPTDEGV-------------------KPRAMYGVEFTFDSDARVAITLYCQAFEEFSNGMAIYSPKSPALVSETVYYKRGVSQQFTLPSFKIDFSEWKEEDLNFDLDRGVFPMVIQAVVDEGD--DCFGHAHVLLAAFERHVD-GSFSVKPLKQKQIVDRVSYLLQEIYGIENKNNQETKPSDDENSDNSNECVVCLSDLRDTLILPCRHLCLCNSCADTLRYQANNCPICRLPFRALLQIRAVRKKPGALSPVSFSPVLAQSMDHDEHS----------------------SSDSVPPGFEPISLLEALNG-------------------------------MGAVSPGVPSAPLYDEINFSGS---LSGESRQLS---------SPDHSGDSAGQKSK-VSKSPDSTLRSPSSPIQEED--------------------------------EEKLS---------EMSDA-----QAHMLLSSSPAPTEGTAGDDAPDSLSPEEEDHLN---------------LDEEAMNDC---SSEHSSFTKTESETPGDLSLP-------GFSDSSESLSTQSTCCSSQPLLGPSSHLHMDDEELDV---------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VY98-1", "uniprot_id": "Q9VY98_DROME", "id": "Q9VY98-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MGNFVSRQNAAVEEADPSTNNAYKYPPR-MGNFFGTHFIMGGERFDTPQPESYLFGENADLNFLGNRPTAFPYPPPQANEPTKTLKSLVNIRKESVRFVKTMNDKKLGGVLEKPKMKEIDRDLDLDKEKSNVTIEDVDGNVLCSMGLGGGDADMTPPPPPCSYNIEFTFDSDAKCAITIYYFCSEDVSPSGVTLVPRE-GLTSETYHYEKGINQCFSQPSHVFNPQQMPEDELGYSPGREQYPVAIHCVVEEGS--DECRQSHTTICVIDHHPENGSYVLRALKQKIFVDGLCYLLQEIYGIENKAVNKTS-LDEEIDDHGSECVICMSETRDTLILPCRHLCLCNSCADSLRYQANNCPICRAPFRALLQIRAVQKG---ISTHVLHQNTPTSAAGEPAP------------------------VDVPPGYIPVSLIEALNGPPQYVARARNSEHDVTDSAATVAASTMTSADIKATSPIKSSSQRRPKIKKNASTCTSTSEVGTITNQSGGGNGSSTHSVEIESDPKKSSTATCTSPTLGASTSPEPKQDKLQIVNERKYPRSTAGSGGDGSAGTDDDVDSENEKLSPLLSPGSKSKNVSSKSLKQVVACLEADDDVDNKSSTGDGPTEESSLKKGSSIKRTKPRPELSGSGAPSPAEATAEDSDYYTPEDTQNSILSPLCPTERAKSGDPLGAGSLGNGGLSVGRSAGSVGGQAGVGPVVVGFSSAVKKNLHKKSTSVGNMVGSGSVTTVVDLKSNNVSSLPDMLDSPISGNSASTRSSSDSYSSSSSTKQLLSSNPTTTAANIIVDDKTALQNAVNV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.::**: *.**: * .:*.**:***: **:*.:**:****:****:**.****** ******.**. *** .* .:**.***:*******:*:*:*: *:.:: . :: * *.:*****:**: ***:* . *:. . . :. .* *** :*::*:.* *: **. :: .: :::*.:. .* :*:.*:.**:**. : ::*. :..:::* : **: ::.**** :** :.************ ::*. *:* .*:..***:*:*: **************.****:************ ***********:* :*. : . * : . .:***: *:**:***** : *.** .*: :*. .. : :: . . .. * :.....** :.: * ::* :**** : .: . .. :. : : :: : . :* :.:. * : . .:. . *:. . ", "identical_positions": 198, "similar_positions": 172, "identity": "24.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110404-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18858-1", "uniprot_id": "DNLI1_HUMAN", "id": "P18858-1", "name": "DNA ligase 1", "aln": "MQRSIMSFFHPKK-----EGKAK------KPEKEASNSSRETEPPPKAALKEWNGVVSESDSP-----VKRPGRKAARVLGSEGE---EEDEALSPAKGQKPALDCSQVSPPRPATSPENNASLSDTS---------PMDSSPSGIPKRRTARKQLPKRTIQEVLE-----------------------------------------------EQSEDEDRE------------AKRKKE----EEEEETPKESLTEAEVATEKEGEDGDQPTTPPKPLKTSKAETPTESVS--------------EPEVATKQELQ-EEEEQTKPPRRA----------------------PKTLSSFFTPRKPAVKKEVKEEEPGAPGKEGAAEGPLDP--------------SGYNPAKNNYHPVEDACWKPGQKVPYLAVARTFEKIEEVSARLRMVETLSNLLRSVVALSPPDLLPVLYLSLNHLGPPQQGLELGVGDGVLLKAVAQATGRQLESVRAEAAEKGDVGLVAENSRSTQRLMLPPPPLTASGVFSKFRDIARLTGSASTAKKIDIIKGLFVACRHSEARFIARSLSGRLRLGLAEQSVLAALSQAVSLTPPGQEFPPAMVDAGKGKTAEARKTWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGIPLKPMLAHPTRGISEVLKRFEEAAFTCEYKYDGQRAQIHALEGGEVKIFSRNQEDNTGKYPDIISRIPKIKLPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVREPLSRRRQLLRENFVETEGEFVFATSLDTKDIEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLASYDEDSEELQAICKLGTGFSDEELEEHHQSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQSQIQNQQGEDSGSDPEDTY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P37913-1", "uniprot_id": "DNLI1_MOUSE", "id": "P37913-1", "name": "DNA ligase 1", "aln": "MQRSIMSFFQPTK-----EGKAK------KPEKETPSSIREKEPPPKVALKERNQVVPESDSP-----VKRTGRKVAQVLSCEGE---DEDEAPGTPKVQKPVSDSEQSSPPSPDTCPENSPVFNCSS---------PMDISPSGFPKRRTARKQLPKRTIQDTLE-----------------------------------------------EQNEDKTKT------------AKKRKK----EEE--TPKESLAEAEDIKQKEEKEGDQLIVPSEPTKSPESVTLTKTEN--------------IPVCKAGVKLKPQEEEQSKPPARG----------------------AKTLSSFFTPRKPAVKTEVKQEESGTLRKE-ETKGTLDP--------------ANYNPSKNNYHPIEDACWKHGQKVPFLAVARTFEKIEEVSARLKMVETLSNLLRSVVALSPPDLLPVLYLSLNRLGPPQQGLELGVGDGVLLKAVAQATGRQLESIRAEVAEKGDVGLVAENSRSTQRLMLPPPPLTISGVFTKFCDIARLTGSASMAKKMDIIKGLFVACRHSEARYIARSLSGRLRLGLAEQSVLAALAQAVSLTPPGQEFPTVVVDAGKGKTAEARKMWLEEQGMILKQTFCEVPDLDRIIPVLLEHGLERLPEHCKLSPGVPLKPMLAHPTRGVSEVLKRFEEVDFTCEYKYDGQRAQIHVLEGGEVKIFSRNQEDNTGKYPDIISRIPKIKHPSVTSFILDTEAVAWDREKKQIQPFQVLTTRKRKEVDASEIQVQVCLYAFDLIYLNGESLVRQPLSRRRQLLRENFVETEGEFVFTTSLDTKDTEQIAEFLEQSVKDSCEGLMVKTLDVDATYEIAKRSHNWLKLKKDYLDGVGDTLDLVVIGAYLGRGKRAGRYGGFLLAAYDEESEELQAICKLGTGFSDEELEEHHQSLQALVLPTPRPYVRIDGAVAPDHWLDPSIVWEVKCADLSLSPIYPAARGLVDKEKGISLRFPRFIRVRKDKQPEQATTSNQVASLYRKQSQIQNQQSSDLDSDVEDY-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "B0S533-1", "uniprot_id": "B0S533_DANRE", "id": "B0S533-1", "name": "DNA ligase", "aln": "MQRSIASFFQPMKGKEKSDGQAKGKPGPVKSPLKIQNGVQESDSPIKKVHKRSRAILDSDEEDGDQPMVKEQEPKQSEVQTVKKEKISDVKTAEVTKASSTPVSPKSPKTPTTPVTSSTSVSVVTPASSGTPGTPATPTSVSPSGIPKRKTARKQFPKRKLESRSDGEELKEEEKEVDGGQESKRARVDSSPEQTENEMMEVDETSADEKTAVEEKEDKAKTSVVVDSEMKDEDDKKQKINTNNEAKEKDKNESKQEEKIDTEKETKEKDKKINKQQEKKETKKETKEKDKSDKKQEEKDKSDKKQEEKDKTEEKVNGENEKEKIPDKKGKESSSPEKVVKKEKDTDGGSAKKKPISSFFAPRKAAVKLEKEERNEGEKKKDGETSDVVEQKEKKSEKGVDSAVQSQYDPSRAHYHPIDHACWKKGQKVPYLAVARTFEKIEEDSGRLKNIETLSNFLRSVILLSPDDLLCCVYLCLNQLGPAYQGLELGIGETVLMKAVAQATGRQLDKIKAEAQEKGDLGLVAESSRSNQRMMFAPANLTAGGVFNKLKEIAHMSGNSAMNKKIDIIKGLFVACRFSEARYIVRSLAGKLRIGLAEQSVLAALSQAVCLTPPGQEFPPAVLDAGKGMSTENRRVFLEEKALILKQTYCEMPNYDAIIPVLLKEGIDELPNHCKLTPGVPLRPMLAHPTKGVGEVMKRFDEASFTCEYKYDGERAQIHILENGEVRIFSRNQEDNTSKYPDIISRIPQVKKESVRSCVLDSEAVAWDREKKQIQPFQVLTTRKRKDVDASEIKVQVCVYAFDLLYLNGESLVREPLSKRRALLRESFVEKEGEFVFARSLDADNTETIAEFLEQSVRDSCEGLMVKTLEKHATYEIAKRSHNWLKLKKDYLEGVGDTVDLCVIGAYLGKGKRAGGYGGFLLACYDEENEEFQSVCKIGTGFKDEDLEQHYNFLKEHILPKPRPYYRVDQSAEPDVWLEAVQVWEVKCADLSLSPVYKAAMGLVDPEKGISLRFPRFLRIRDDKKPEDATTGSQIADLYKKQQQIQNQGDK---PDLEDYY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***** ***:* * :*:** *. : .. :*.:.* * . *. . :: ..:. **. * :.* : * : . * . ..*. . :*. * *.. . . .. :* * . ****:***:*****:***.::. : *:.**: : *::* * : :** * : .:** :: *: : * .: * : . : ::: ::*::. * :. *.:****:***.*** * ::.: * *: :.. :: : *:*:: :***::.**** *****:************ *.**: :*****:****: *** *** :**.**:***. ******:*: **:***********:.::**. ****:*****.***.**:*:.*. ** .***.*: :**:::*.:: **:***********.****:*.***:*:**:***********:***.*********..::***** ::* *: :***:.:*****:**:*: * ******:.*::.**:****:**:**:*******:*:.**:***:*. *********:***** **.***:**********.**********::* ** * :**:************************:******:****:*****:*********:***:** ****.***.******: ***:.: * *********:***********: .********************:*****:** *******:***** *******.***:.**:*::**:****.**:**:*:: *: :**.**** *:* :. ** **:. *************:* ** **** :**********:*:*.**:**:***. *:* **:**.***** .. .* ** ", "identical_positions": 534, "similar_positions": 234, "identity": "50.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110406-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05997-1", "uniprot_id": "CO5A2_HUMAN", "id": "P05997-1", "name": "Collagen alpha-2(V) chain", "aln": "MMANWAEARPLLILIVLLGQFVSIKAQEEDEDEGYGEEIACTQNGQMYLNRDIWKPAPCQICVCDNGAILCDKIECQDVLDCADPVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGDIMG--------HYDESMPDPLPEFTEDQAAPDDKN---KTDPGVHATLKSLSSQIETMRSPDGSKKHPARTCDDLKLCHSAKQSGEYWIDPNQGSVEDAIKVYCNMETGETCISANPSSVPRKTWWASKSPDNKPVWYGLDMNRGSQFAYG-DHQSPNTAITQMTFLRLLSKEASQNITYICKNSVGYMDDQAKNLKKAVVLKGANDLDIKAEGNIRFRYIVLQDTCSKRNGNVGKTVFEYRTQNVARLPIIDLAPVDVGGTDQEFGVEIGPVCFV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FE47-1", "uniprot_id": "E7FE47_DANRE", "id": "E7FE47-1", "name": "", "aln": "-MRGVHHLRIPVWLGICLAQVLLITCQEVKIEDAKG----CKDGDLTYSENEIWKPEPCRLCVCDKGTVICEEIRCEELKGCEQFLIPEGECCPVCQTFASAHGRIETLAFKGQKGEPGDIPYIVGIPGRPGPMGPPGTDGRPGYPGSKGRRGVPGPPGFDGEPGVPGMPGEPGPIG-TSLPGSQ-----FASHMASGFQGGKLG-LAGMVTGAPGESGSRGLPGPAGPPGPTGAQGAPGDAGDPGPMGSFGPRGPDGSPGKAGSDGEPGPPGNAGEKGYPGSPGSRGFPGLPGQPGLKGSKGQLGLQGMKGEPGAVGSKGESGSPGTMGLVGPPGPIGMTGERGRIGPTGTVGKRGLSGNVGKPGPLGPMGISGGPGFPGSPGMKGQAGATGPRGPSGLQGPRGESGRQGSPGKQGTQGSAGPDGTPGVKGPAGIPGVQGPVGLIGQPGLPGPQGSPGLTGAKGQLGDLGSPGFKGEPGAKGEVGPPGVQGEMGPTGEEGKRGPRGDGGAVGAPGPNGERGAPGNRGFPGADGLPGPKGAQGERGLPGSSGPKGTSGDPGRPGETGIPGARGLTGALGMQGAEGKIGPQGAPGDDGNPGPAGSTGTRGAAGSMGLPGPKGFSGDPGKAGETGSSGAPGQRGPNGKDGEEGPAGTTGPPGVAGKRGEQGPPGLTGFQGLPGPPGPPGQSGKPGDEGIHGEEGGPGLTGPRGERGTPGERGDPGPNGLPGAKGSAGGPGHDGPKGKHGPAGIVGEPGPPGLQGMPGERGISGPAGPKGESGAIGDRGGEGAAGNDGVRGLPGPVGPIGPAGPSGEKGEQGPRGPSGSPGSRAMPGSPGEPGPIGPVGFAGPPGPDGQPGVKGETGEEGAKGEGGSPGPQGMAGKPGPQGVVGITGLKGGRGTQGAAGPSGFPGFAGGVGPAGSAGPVGEPGPIGAPGKEGPSGIPGEPGGPGRQGELGNPGPAGGPGDKGEPGEDGLPGPDGPPGPGGTPGQRGLVGLPGMRGERGMAGLPGPAGPPGKAGTQGPHGTKGGAGPIGLPGAAGPRGDAGAEGLPGAEGVQGADGIIGVRGDRGDSGPEGLAGGQGASGSQGPVGTPGGPGQRGHQGARGPPGADGAAGIRGKKGPQGPMGDKGEKGEAGDRGQKGHRGFTGLSGLPGAPGAPGDDGAIGIIGPSGQRGPPGPAGPPGKEGDIGPPGALGPPGSRGASGDFGPAGPTGEPGPPGPPGAPGPPIAAVDDLFGTNFDLDVESEPEEPPPPPPEFNEDEARPNNGSEAVRVDSGLHLSLKSLGSQLDSMRSPDGTRQYPARTCQDLKQCYPLKKSGDYWIDPNEGSTRDAIQVYCNMEMGETCIPANPASVPRKNWWTSQSSNQKPVWFGATMNRGTKFTYGNKEASANAVSVQLRFLRLLSKEASQSVTYHCKNTVAYKDEKNSNLKKALILKASDGQDIKAYNSNRLKYTVTADGCSKPNGEWGRTVFEYRTQTLSRLPIVDLAAVDVGGRDQEFGIDIGHVCFS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . * : * : *.*.: *..** . ::. * *.:.. * :.:**** **::****:*:::*::*.*::: .* : : * *******. ... . . ******** :* :.** ***** ****::* * *.*** * ** *:******** ** *** * .* **.: *:::**. : . ** .*::.*: * *.** * * * :*. *.**:.*******.:*.***:*.***.*.***** **.** *:.****:***** ** ***** :*: **:* *** ** *****:*..*.** :** ** **.*****:** *: *:** * *****:**:**.*..****.*****:**.**.***.* ** ***:* *. *. * *: *.*****.***:* **..** * * ** ******.* * :** ** * ******.*.*** ** *:** :**.*********** *:**.*** *************:************** *******:.********.*:******** *:**.***:** ****:**.***.** * ** .********** ******.**:*.:*.*****. ***** **:*..****:**:******** **************:.*****:*: *: *. * *******.*****:** .**** ** *** * *****. **:* *:.**************:*..****: *.**::*.**:*****.******:** *****:***** **** *.****. *** ** ** *.****** ***********.** * **:.*******:**.***:* *:.**********..*.:**** ** ***.*.**. * .**:* ******.*: *:**. ** *: * .**.*******:***** *********.**.****:**:** ******.*******.***.*. *. * ** .**:* **: ** *:.*.** .* :*. * ** :* ******.** **.*.***.*: ****:**..****. *:*** *. * ** ** ***** ****::*: **************.****.**. *::*: ** ** * ******.**.****: ** *.:**** **: *: ** **.**********.** **:.*::* *. * * ***.**:* *:: . :.*.*:* :****.**:::******::::*****:*** *:. *:**:******:**..***:****** *****.***:*****.**:*:*.::****:* ****::*:** .. *.*:. .*: ***********.:** ***:*.* *:: .*****::**.::. **** .. *::* * * *** **: *:********.::****:***.***** *****::** *** ", "identical_positions": 938, "similar_positions": 320, "identity": "62.08%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110406-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HC10-1", "uniprot_id": "OTOF_HUMAN", "id": "Q9HC10-1", "name": "Otoferlin", "aln": "MALLIHLKTVSELRGRGDRIAKVTFRGQSFYSRVLENCEDVADFDETFRWPVASSIDRNEMLEIQVFNYSKVFSNKLIGTFRMVLQKVVEESHVEVTDTLIDDNNAIIKTSLCVEVRYQATDGTVGSWDDGDFLGDESLQEEEKDSQETDGLLPGSRPSSRPPGEKSFRRAGRSVFSAMKLGKNRSHKEEPQRPDEPAVLEMEDLDHLAIRLGDGLDPDSVSLASVTALTTNVSNKRSKPDIKMEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPDDISSGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDKGFLPTLGPAWVNMYGSTRNYTLLDEHQDLNEGLGEGVSFRARLLLGLAVEIVDTSNPELTSSTEVQVEQATPISESCAGKMEEFFLFGAFLEASMIDRRNGDKPITFEVTIGNYGNEVDGLSRPQRPRPRKEPGDEEEVDLIQNASDDEAGDAGDLASVSSTPPMRPQVTDRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDIQEMIKTEKSYPERRLRGVLEELSCGCCRFLSLADKDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFSIVEEETGKDCAKVKTLFLKLPGKRGFGSAGWTVQAKVELYLWLGLSKQRKEFLCGLPCGFQEVKAAQGLGLHAFPPVSLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYRGNATAGDLLAAFELLQIGPAGKADLPPINGPVDVDRGPIMPVPMGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLRRFIYRPPDRSAPSWNTTVRLLRRCRVLCNGGSSSHSTGEVVVTMEPEVPIKKLETMVKLDATSEAVVKVDVAEEEKE-KKKKKKGTAEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQQEPSGIDLEEKEEVDNTEGLKGSMKGKEKARAAKEEKKKKTQSSGSGQGSEAPEKKKPKIDELKVYPKELESEFDNFEDWLHTFNLLRGKTGDDED---GSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDSTYGMFQGIPSNDPINVLVRVYVVRATDLHPADINGKADPYIAIRLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSTHGYNIWRDPMKPSQILTRLCKDGKVDGPHFGPPGRVKVANRVFTGPSEIEDENGQRKPTDEHVALLALRHWEDIPRAGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIIWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVISKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKLLLLLLLLLLLALFLYSVPGYLVKKILGA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9ESF1-1", "uniprot_id": "OTOF_MOUSE", "id": "Q9ESF1-1", "name": "Otoferlin", "aln": "MALIVHLKTVSELRGKGDRIAKVTFRGQSFYSRVLENCEGVADFDETFRWPVASSIDRNEVLEIQIFNYSKVFSNKLIGTFCMVLQKVVEENRVEVTDTLMDDSNAIIKTSLSMEVRYQATDGTVGPWDDGDFLGDESLQEE-KDSQETDGLLPGSRPSTRISGEKSFRRAGRSVFSAMKLGKTRSHKEEPQRQDEPAVLEMEDLDHLAIQLGDGLDPDSVSLASVTALTSNVSNKRSKPDIKMEPSAGRPMDYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPDDISAGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDKGFLPTLGPAWVNMYGSTRNYTLLDEHQDLNEGLGEGVSFRARLMLGLAVEILDTSNPELTSSTEVQVEQATPVSESCTGRMEEFFLFGAFLEASMIDRKNGDKPITFEVTIGNYGNEVDGMSRPLRPRPRKEPGDEEEVDLIQNSSDDEGDEAGDLASVSSTPPMRPQITDRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDVQEMIKTEKSYPERRLRGVLEELSCGCHRFLSLSDKDQGRSSRTRLDRERLKSCMRELESMGQQAKSLRAQVKRHTVRDKLRLCQNFLQKLRFLADEPQHSIPDVFIWMMSNNKRIAYARVPSKDLLFSIVEEELGKDCAKVKTLFLKLPGKRGFGSAGWTVQAKLELYLWLGLSKQRKDFLCGLPCGFEEVKAAQGLGLHSFPPISLVYTKKQAFQLRAHMYQARSLFAADSSGLSDPFARVFFINQSQCTEVLNETLCPTWDQMLVFDNLELYGEAHELRDDPPIIVIEIYDQDSMGKADFMGRTFAKPLVKMADEAYCPPRFPPQLEYYQIYRGSATAGDLLAAFELLQIGPSGKADLPPINGPVDMDRGPIMPVPVGIRPVLSKYRVEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIHNYKKNPNFNTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVSSLRRFIYRPPDRSAPNWNTTVRLLRGCHRLRNGGPSSRPTGEVVVSMEPEEPVKKLETMVKLDATSDAVVKVDVAEDEKERKKKKKKGPSEEPEEEEPDESMLDWWSKYFASIDTMKEQLRQHETSGTDLEEKEEMESAEGLKGPMKSKEKSRAAKEEKKKKNQSPGPGQGSEAPEKKKAKIDELKVYPKELESEFDSFEDWLHTFNLLRGKTGDDED---GSTEEERIVGRFKGSLCVYKVPLPEDVSREAGYDPTYGMFQGIPSNDPINVLVRIYVVRATDLHPADINGKADPYIAIKLGKTDIRDKENYISKQLNPVFGKSFDIEASFPMESMLTVAVYDWDLVGTDDLIGETKIDLENRFYSKHRATCGIAQTYSIHGYNIWRDPMKPSQILTRLCKEGKVDGPHFGPHGRVRVANRVFTGPSEIEDENGQRKPTDEHVALSALRHWEDIPRVGCRLVPEHVETRPLLNPDKPGIEQGRLELWVDMFPMDMPAPGTPLDISPRKPKKYELRVIVWNTDEVVLEDDDFFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRYLFPFDYLAAEEKIVMSKKESMFSWDETEYKIPARLTLQIWDADHFSADDFLGAIELDLNRFPRGAKTAKQCTMEMATGEVDVPLVSIFKQKRVKGWWPLLARNENDEFELTGKVEAELHLLTAEEAEKNPVGLARNEPDPLEKPNRPDTSFIWFLNPLKSARYFLWHTYRWLLLKFLLLFLLLLLFALFLYSLPGYLAKKILGA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9P0R6-1", "uniprot_id": "A0A8M9P0R6_DANRE", "id": "A0A8M9P0R6-1", "name": "Otoferlin", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKRNKHRSSKDDGKGQDEPAILETEDMRMP--------DPDTISLASVTAVTTNVSNKRSKPDIKIEPSAGRPMDFQVSVTVIEARQLVGLNMDPVVCVEIGDDKKYTSMKESTNCPYYNEYFVFDFHVPPDVMFDKILKVSVIHSKNLLRSGTLVGSFKLDVGTIYTQPDHQFFHKWATLCDPEDITAGLKGYVKCDIAVVAKGDTIKTPHKANENDEDDIESNLLLPEDVPAERQWARFYLKIYRAEGLPKMNTSIMANVKKAFIGENKDLVDPYVQVLFAGQKGKTSIQKSSYEPIWNEQIVFTEQFPPLCRRMKLQIRDSDKVNDVAIGTHFIDLRKIANDGDKGFLPTLGPAWVNMYGSTRSYTLMDEYQDLNEGLGEGVSFRARLLISLAVEILDTSSPEVMSSTEVQVEGIPNISDNATGKVEEFFLFGSFLEATMIDRKIGDKPINFEVTIGNYGSELDTPTKP-KSKKKKGDGDDEESELIHGSSDEEVDDGGDVTSVSTTPPMKPVITDRNYFHLPYFERKPCIYIYSWWQDQRRRLYNANVLDKMADKLEEGLNDVQEIIKTEKAYPERRLRGVLEELSNSCSTFVSLANNDQNQAGRTKLDKERVKLCMQEVESMGQQAKTMRSQVKKSNVKDRIKLAQNFLHKLRFLSDEPQHSVPDIYIWMISNNKRIAYARVPSKDILYSSVEEECGKDCGKVQTIFFKLPGKKSFGPAGWTVQAKTELYLWLGLNRQRKDYLCGLPNGFEENKAVKGPGVQSSPPISLMYTMKQIFQLRVHMYQARSLFAADSTGLSDPFARIFFSTHSQVTEVLNETLCPTWDQLLVFDHVELYGEAGELRDDPPIIVIEIYDQDTVGKADFMGRTFAKPITKMSDEHYGPPRFPPQLEYYQIYRGNCTAGEMLAAFELLQIGPGGKADLPPIDGPTDIDRGPILPVPIGIRPVLSKYRIEVLFWGLRDLKRVNLAQVDRPRVDIECAGKGVQSSLIQNYKKNPNFSTLVKWFEVDLPENELLHPPLNIRVVDCRAFGRYTLVGSHAVTTLRKFIYRPADKSVNNWS--------------------AMEEVVIHTEPEPAVKKIETVVKLDSASDAVVKVDMPDDEKGGKGKKKRKKGEEVEEEELDESMLDWWSKYFASIETLKEAMKAQEA---EAEEKEDFESGDGKK------------KRGKKSKTIP-----GEAVPEKKKQKIEEFKVYNRELEYEYNQFEDWLHTFNLHRGKCSDDADVDQNAADEDRLIGKFKGSLCIYKVSS-DDMSRDMGFDSNMGMFQNIPHNDPINVLVRIYVVRATDLHPADINGKADPYIAIKLGKSEIKDKENYISKQLNPVFGKSFDVEATLPMDSTLTVSIYDWDLVGTDDLIGETKIDLENRFYSKHRATCGISSTYAIHGYNVWRDPLKPSHILAKLCKDGKIDAPQYGPGGRVKVTNRVYTGPTEVEDENGLKKQTDEHLALAVLNHWEDIPRIGCKLVPEHMETRPLLNPDKPGIEQGRIEMWVDMFPKDMSAPGPALDISPRKPKKFELRVIVWNTDEVVLEDDDIFTGEKSSDIFVRGWLKGQQEDKQDTDVHYHSLTGEGNFNWRFIYPFDYLQAEEKIVISKKESMFSWDETEYKIPARLNLQVWDADHFSADDFLGAIELDLNRFPRGAKTAKQCSIEMVTNENEMPMVNIFKQKRIKGWWPFVARDENDELEITGKVEAELQLLTGEEAEKSPVGEGRNEPEPLEKPNRPDTAMLWFLMPLKAIRHLVCNQYKWLAIKLVLALMLLAILGLFLYSMPGYMVKKLLGA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** .* ** *:: : ****:** **: ***::*******:*:************:*********:***:********************:****************************.********:*:*******************:****:*:**:***.**** *.**:**::*********:***.***.*********.******.******.**.********:*********:****:**********************:*********:*******:****:***: *****:***:***********************:***********************.***:**:*****************::.*****:***.**: ******** . :*:..:*::*******:****:****: *****.*********.*:* ::* :.: :* **:** :**:.:**:* .:.**::***:****:* :**********:******** *** **********::*::**********:**:*****:************** .* *:**:::**.::.**:**:**:* **:*:*.*****: :*:***: .*:*:::*.****:*****:******:**::***:*****:*********:*:* **** ****.**:*:*:*****:.**.******** ********.:***::***** **:* **.:* *::: **:**:** ** ****.*************:********:** .:** **************:****::****** *****************::*************:.**:** * ****************..***::***********.********:**.*:*****:***:**********:*************************************:********.*****************************************::**:*****.*:*. .*. . ***: *** .:**:**:****::*:******:.::** * ***: .** **** ***************:*:** :: :*. : ****:.:. :* * *. **.*. . *. .***** **:*:*** :*** *::.********** *** .** * .:::*:*::*:******:***. :*:**: *:*.. ****.** *********:***********************:***::*:*******************:**::**:* ***::*********************************:.**: ****:****:***:**::***:**:*.*::** ***:*:***:***:*:***** :* ****:** .*.******* **:*****:*****************:*:****** **.***..**********:*****:************:*****************************************:::***** ******:********************.**:********************************::**.*.* ::*:*.******:*****::**:****:*:********:***.*****.*** .****:**********:::*** ***: *::: : *:** :*::* ::** ::.*****:***:.**:***", "identical_positions": 1346, "similar_positions": 328, "identity": "67.27%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110407-10", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P0K8-1", "uniprot_id": "PLAK_RAT", "id": "Q6P0K8-1", "name": "Junction plakoglobin", "aln": "---MEVMN----------------LIEQPIKVTEWQQT-YTYDSGIHSGVNTCVPSVSSKGLLDEDDTCGRQYTLKKTTTYTQGVPQSQGDLEYQMSTTARAKRVREAMCPGVSGEDSSLLLATQVEGQTTNLQRLAEPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANGGPQGLVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLENVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVA----AGTQQP--YTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRISEDKNPDYRKRVSVELTNSLFKHDPAAWEAAQSMIP------INEPYA-DDMDATYRP-------------MYSSDVPLDPLD-----------------------------------------------MHMDMDGDYPMDTYSDGLRPPYPAADHMLA--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02257-1", "uniprot_id": "PLAK_MOUSE", "id": "Q02257-1", "name": "Junction plakoglobin", "aln": "---MEVMN----------------LIEQPIKVTEWQQT-YTYDSGIHSGVNTCVPSVSSKGIMDEDDACGRQYTLKKTTTYTQGVPQNQGDLEYQMSTTARAKRVREAMCPGVSGEDSSLLLATQVEGQTTNLQRLAEPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANGGPQGLVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVA----AGTQQP--YTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRISEDKNPDYRKRVSVELTNSLFKHDPAAWEAAQSMIP------INEPYA-DDMDATYRP-------------MYSSDVPLDPLD-----------------------------------------------MHMDLDGDYPMDTYSDGLRPPYPTADHMLA--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14923-1", "uniprot_id": "PLAK_HUMAN", "id": "P14923-1", "name": "Junction plakoglobin", "aln": "---MEVMN----------------LMEQPIKVTEWQQT-YTYDSGIHSGANTCVPSVSSKGIMEEDEACGRQYTLKKTTTYTQGVPPSQGDLEYQMSTTARAKRVREAMCPGVSGEDSSLLLATQVEGQATNLQRLAEPSQLLKSAIVHLINYQDDAELATRALPELTKLLNDEDPVVVTKAAMIVNQLSKKEASRRALMGSPQLVAAVVRTMQNTSDLDTARCTTSILHNLSHHREGLLAIFKSGGIPALVRMLSSPVESVLFYAITTLHNLLLYQEGAKMAVRLADGLQKMVPLLNKNNPKFLAITTDCLQLLAYGNQESKLIILANGGPQALVQIMRNYSYEKLLWTTSRVLKVLSVCPSNKPAIVEAGGMQALGKHLTSNSPRLVQNCLWTLRNLSDVATKQEGLESVLKILVNQLSVDDVNVLTCATGTLSNLTCNNSKNKTLVTQNSGVEALIHAILRAGDKDDITEPAVCALRHLTSRHPEAEMAQNSVRLNYGIPAIVKLLNQPNQWPLVKATIGLIRNLALCPANHAPLQEAAVIPRLVQLLVKAHQDAQRHVA----AGTQQP--YTDGVRMEEIVEGCTGALHILARDPMNRMEIFRLNTIPLFVQLLYSSVENIQRVAAGVLCELAQDKEAADAIDAEGASAPLMELLHSRNEGTATYAAAVLFRISEDKNPDYRKRVSVELTNSLFKHDPAAWEAAQSMIP------INEPYG-DDMDATYRP-------------MYSSDVPLDPLE-----------------------------------------------MHMDMDGDYPIDTYSDGLRPPYPTADHMLA--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PS81-1", "uniprot_id": "A0A8M9PS81_DANRE", "id": "A0A8M9PS81-1", "name": "", "aln": "--MSLQMS----------------EADGAVKVEEWQQSFYTADSGIQSGATT---------IRDEDESESRKYSAGESS----------ADMEAQFSLT-RAQRVRAAMFPETLVEGETVLTPQSNPDQPTNVQRLAEPSQLLKTAIVHLINYQDDAELATRAVPELTKLLADDDQVVVNKAALIVNQLTRKEASRRVLMQSPQMVSAVVRAMQNTGDLETARCAASVLHSLSHQREGLLAIFKSGGIPALVRMLSSPMESVLFYAITTLHNLLLHQEGAKMAVRLADGLQRMVPLLKKTNPKFLAITTDCLQLLSYGNQESKLIILANGGPECLVFIMRNYNYEKLLWTTSRVLKVLSVCPSNKPAIVDSGGMQALGQHLTGSSQRLTQNCLWTLRNLSDAATKQEGLDGLLQILVSQLGSDDVNMLTCATGILSNLTCNNARNKALVTQSGGVEALIHAVLRAGEKEDVAEPAVCALRHLTSRHPDAELAQNAVRLHYGIPAITKLLGQPHYWPVVKATVGLIRNLALCPANQAPLRESGAIPRLVNLLLKAHQETQRHG-----SGAQQT--YQDGVRMEEIVEGCTGALHILARDPMNRGEIASMQTIPLFVQLLYSYVENIKRVSAGVLCELALDKQSAEMIDAEGASAPLMELLHSPNEGIATYAAAVLFRISEDKSSDYRKRVSVELTHSLFKHDPAAWDMAHAAMP------LDPGYIPDDLDVVYPP-------------YGYSDLPMDGLP-----------------------------------------------LEAELHEQYMPEMAYD-PRQVYPNPL------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P18824-1", "uniprot_id": "ARM_DROME", "id": "P18824-1", "name": "Armadillo segment polarity protein", "aln": "MSYMPAQNRTMSHNNQYNPPDLPPMVSAKEQTLMWQQNSYLGDSGIHSGAVTQVPSLSG---KEDEEMEGDPLMFDLDTGFPQNFTQDQVDDMNQQLSQTRSQRVRAAMFPETLEEGIEIPSTQFDPQQPTAVQRLSEPSQMLKHAVVNLINYQDDAELATRAIPELIKLLNDEDQVVVSQAAMMVHQLSKKEASRHAIMNSPQMVAALVRAISNSNDLESTKAAVGTLHNLSHHRQGLLAIFKSGGIPALVKLLSSPVESVLFYAITTLHNLLLHQDGSKMAVRLAGGLQKMVTLLQRNNVKFLAIVTDCLQILAYGNQESKLIILASGGPNELVRIMRSYDYEKLLWTTSRVLKVLSVCSSNKPAIVDAGGMQALAMHLGNMSPRLVQNCLWTLRNLSDAATKVEGLEALLQSLVQVLGSTDVNVVTCAAGILSNLTCNNQRNKATVCQVGGVDALVRTIINAGDREEITEPAVCALRHLTSRHVDSELAQNAVRLNYGLSVIVKLLHPPSRWPLIKAVIGLIRNLALCPANHAPLREHGAIHHLVRLLMRAFQDTERQRSSIATTGSQQPSAYADGVRMEEIVEGTVGALHILARESHNRALIRQQSVIPIFVRLLFNEIENIQRVAAGVLCELAADKEGAEIIEQEGATGPLTDLLHSRNEGVATYAAAVLFRMSEDKPQDYKKRLSIELTNSLLREDNNIWANADLGMGPDLQDMLGPEEAYEGLYGQGPPSVHSSHGGRAFHQQGYDTLPIDSMQGLEISSPVGGGGAGGAPGNGGAVGGASGGGGNIGAIPPSGAPTSPYSMDMDVGEIDAGALNFDLDAMPTPPNDNNNLAAWYDTDC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :. ***. * ****:**. * :::: . : * * *::*** ** * . *. : . *.* :***:****:** *:*:**************:*** *** *:* ***.:**::*:**::*****:.:* ***:*:*:**::.*:.**::::.:.. **.***:*:***************::****:****************:*:*:*******.***:**.**::.* *****.*****:*:************.***: ** ***.*.******************.*******::******. ** . * **.************.*** ***: :*: **. *. ***::***:* ******** :**: * * .**:**:::::.**::::::************** ::*:***:***:**:..*.*** * **::**.:************:***:* ..* :**.**::*.*:::*: :*:**. * *********** .********:. ** * ..**:**:**:. :***:**:******** **:.*: *: ***:.** :**** *** **********:**** **:**:*:***:**::.* * *. : :. :.: * . :*:* : :. :: * * ", "identical_positions": 402, "similar_positions": 177, "identity": "47.52%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110407-11", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVD4-1", "uniprot_id": "CLCN5_MOUSE", "id": "Q9WVD4-1", "name": "H(+)/Cl(-) exchange transporter 5", "aln": "MAMWQGAMDNRGFHQGSFSSFQSSSSDEDLMDIPGTAMDFSMRDDVPPLDREIEGNKSYNGGGIGSSNRVMDFLEEPIPGVGTYDDFNTIDWVREKSRDRDRHREITNKSKESTWALIHSVSDAFSGWLLMLLIGLLSGSLAGLIDISAHWMTDLKEGICTGGFWFNHEHCCWNSEHVTFEHRDKCPEWNSWAQLIINTDQG--AFAYIVNYFMYVLWALLFAFLAVSLVKAFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLSLGKEGPLVHVACCCGNILCHCFNKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFIVLGIFGGLWGALFIRTNIAWCRKRKTTQLGKYPVVEVLIVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSSKLCDYENH-------FNTSKGGELPDRPAGVGIYSAMWQLALTLILKIVITIFTFGMKIPSGLFIPSMAVGAIAGRLLGVGMEQLAYYHHDWGIFNSWCSQGADCITPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAMTSKWVADALGREGIYDAHIRLNGYPFLEAKEEFAHKTLAMDVMKPRRNDPLLTVLTQDSMTVEDVETIISETTYSGFPVVVSRESQRLVGFVLRRDLIISIENARKKQDGVVSTSIIYFTEHSPPMPPYTPPTLKLRNILDLSPFTVTDLTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDVLKHIAQMANQDPDSILFN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51795-2", "uniprot_id": "CLCN5_HUMAN", "id": "P51795-2", "name": "H(+)/Cl(-) exchange transporter 5", "aln": "MAMWQGAMDNRGFQQGSFSSFQNSSSDEDLMDIPATAMDFSMRDDVPPLDREVGEDKSYNGGGIGSSNRIMDFLEEPIPGVGTYDDFNTIDWVREKSRDRDRHREITNKSKESTWALIHSVSDAFSGWLLMLLIGLLSGSLAGLIDISAHWMTDLKEGICTGGFWFNHEHCCWNSEHVTFEERDKCPEWNSWSQLIISTDEG--AFAYIVNYFMYVLWALLFAFLAVSLVKVFAPYACGSGIPEIKTILSGFIIRGYLGKWTLVIKTITLVLAVSSGLSLGKEGPLVHVACCCGNILCHCFNKYRKNEAKRREVLSAAAAAGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHLFELVPFILLGIFGGLWGALFIRTNIAWCRKRKTTQLGKYPVIEVLVVTAITAILAFPNEYTRMSTSELISELFNDCGLLDSSKLCDYENR-------FNTSKGGELPDRPAGVGVYSAMWQLALTLILKIVITIFTFGMKIPSGLFIPSMAVGAIAGRLLGVGMEQLAYYHQEWTVFNSWCSQGADCITPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAMTSKWVADALGREGIYDAHIRLNGYPFLEAKEEFAHKTLAMDVMKPRRNDPLLTVLTQDSMTVEDVETIISETTYSGFPVVVSRESQRLVGFVLRRDLIISIENARKKQDGVVSTSIIYFTEHSPPLPPYTPPTLKLRNILDLSPFTVTDLTPMEIVVDIFRKLGLRQCLVTHNGRLLGIITKKDVLKHIAQMANQDPDSILFN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6U5-1", "uniprot_id": "A0ACD6B6U5_DANRE", "id": "A0ACD6B6U5-1", "name": "Chloride channel protein", "aln": "-------MDNGGF---CYDNYHSGSSDDELVDISDVTVDY--NEDVPPLDRDYSTGHCKADWRPNSSPKLMDLLD--VSGIGTYEDFNTIDWVREKSRDRDRHREITNKSKHSTLALIFSISDAFSGWLLMLLIGLMSGALAGGIDIAAHWMTDLKEGVCLDGFWFNHEDCCWTYNGTTFKERDKCPQWKSWAELMVGVSESTVWYAYMASYFMYVCWALFFSFLAVILVRAFAPYACGSGIPEIKTILSGFIIRGYLGKWTLIIKTITLVLAVSSGLSLGKEGPLVHVACCCANILCHFFTKYRRNEAKRREVLSAASAVGVSVAFGAPIGGVLFSLEEVSYYFPLKTLWRSFFAALVAAFTLRSINPFGNSRLVLFYVEFHTPWHFLELIPFILLGIFGGLWGAFFIRANIAWCRLRKNTSFGHYPVLEVIIVTLVTAFLAFPNEFTRMSSSTLISELFNDCSLLDSSKLCNYTSVGGGRGGSVNATIANALADRPAGPGLYTAMWQLALALLFKMVMTVATFGMKVPSGLFIPSMAVGAIAGRLLGVFMEQLAVYHHDWAIFRGWCSPGTDCITPGLYAMVGAAACLGGVTRMTVSLVVIMFELTGGLEYIVPLMAAAMTSKWVADAFGRESIYEAHIRLNGYPFLEAKEEFRHKTLATDVMRPRRSDPPLSVLTQSGMSVEEVERLIADTTYSGFPVVLSLTSQRLVGFVLRRDLIISLENARRHQEGVVSVSAVLFTECDPPASPNAPPAVKLRSILDLSPFTVTVHTPMEIVVDIFRKLGLRQCLVTQNGRLLGIITKKDILKHMAQMANRDPDSILFN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** ** .:..::..***::*:**. .::*: .:*******: .:. . .** ::**:*: :.*:***:**************************.** ***.*:***************:**:*** ***:**********:* .*******.***. : .**:.*****:*:**::*::...:. :**:..***** ***:*:**** **:.*******************************:*****************************.***** *.***:************:*.******************************************************************::**:***:**********:***:****** **.*.:*:***:**::** :**:******:****:* *********.********:* . .*:: .. *.***** *:*:*******:*::*:*:*: *****:********************* ***** **::* :*..*** *:*********************************************************:***.**:***************** ***** ***:***.** *:****..*:**:** :*::*********:* ****************:****::*:****.* : *** .** .* :**::***.********** *********************:************:***:*****:********", "identical_positions": 614, "similar_positions": 142, "identity": "74.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110407-17", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYR7-1", "uniprot_id": "ACOT3_MOUSE", "id": "Q9QYR7-1", "name": "Acyl-coenzyme A thioesterase 3", "aln": "------------------------------------------------------------MHAFTTQNPNRMAPTVILEPAGGCLCDQPVHIAVRGLAPEQPVTLRSVLRDEKGALFRAHARYRADSHGELDLARTPALGGSFSGLEPMGLLWAMEPDRPFWRLIKRDVQTPFVVELEVLDGHEPDGGQRLARAVHERHFMAPGVRRVPVREGRVRATLFLPPGTGPFPGIIDLFGIGSGLLEYRASLLAGKGFAVMALAYNNYEDLPKDMDIIHLEYFEEAVTYLLSHPQVTGSGVGVLGISKGGELGFAMASFLKN-ITAAVIINGSISNIGGNLQYKDETVPSVGINTKRVKRTKDGLKDIVDLLNNPLEGPDQKSLIPVERSDTAFLFLVGQDDHNWKSEFYAREASKRLQAHGKEKPQIICYPETGHHIEPPYFPLCKASLNSLVGGPVIWGGEPRAHAMAQVDAWQQLQTFFHNHLDGKKKTIPAKL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A6H9-1", "uniprot_id": "A0A8I6A6H9_RAT", "id": "A0A8I6A6H9-1", "name": "", "aln": "------------------------------------------------------------MHAFTTQN--RMAPTVILEPAVGCLCDQPVHITVRGLGPEQPVTLRAALRDEKGALFRAHARYRADAHGVLDLERAPALGGSFTGLEPMGLIWAMEPERPFWRLVKRDVQTPFVVELEVLDGHEPDGGRLLAQAVHERHFMAPGVRRVPVREGRVRATLFLPP---------DLFGLGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKDVDIIHLEYFEEAVNYLLSHPQVKGSGVGVLGISKGGELGFAMATFLKN-ITAAVIINGSVANVGGTLQYRDETILPVGMSTKRIKRIKDGLKDIVDALNNPLEGADQKSLIPVERSDTTFLFLVGQDDHNWKSEFYAREASKRLQAHGKEKPQIICYPETGHYIEPPYFPLCKASLHSLVGGPVIWGGEPRAHAMAQVDAWQQLQTFFHKHLGGEKKTIPAKL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55171-1", "uniprot_id": "ACOT2_RAT", "id": "O55171-1", "name": "Acyl-coenzyme A thioesterase 2, mitochondrial", "aln": "------------------------MVASSFAVLRASR----LCQWGWKSWTQLSGPPPLSTGGRTT--FARTNATLSLEPGSRSCWDEPLSITVRGLAPEQPVTLRAALRDEKGALFRAHARYRADAGGELDLARAPALGGSFTGLEPMGLIWAMEPERPLWRLVKRDVQKPYVVELEVLDGHEPDGGQRLAQAVHERHFMAPGVRRVPVRDGRVRATLFLPPEPGPFPEIIDLFGVGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKTMETMRIEYFEEAVNYLRGHPEVKGPGIGLLGISKGGELGLAMASFLKG-ITAAVVINGSVAAVGNTVCYKDETIPPVSLLRDKVKMTKDGLLDVVEALQSPL--VDKKSFIPVERSDTTFLFLVGQDDHNWKSEFYAREASKRLQAHGKEKPQIICYPEAGHYIEPPYFPLCSAGMHLLVGANITFGGEPKPHSVAQLDAWQQLQTFFHKQLSGKS--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QYR9-1", "uniprot_id": "ACOT2_MOUSE", "id": "Q9QYR9-1", "name": "Acyl-coenzyme A thioesterase 2, mitochondrial", "aln": "------------------------MVASSFAVLRASR----LCQQDWKSWARLFVPPPLSTGGRTT--WARTNATLSVEPEGRSCWDEPLSIAVRGLAPEQPVTLRSALRDEKGALFRAHARYRADAGGELNLARAPALGGSFSGLEPMGLLWAMEPERPLWRLIKRDVQTPFLVELEVLDGHEPDGGQRLAQAVHERHFLAPGVRRVPVREGRVRATLFLPPEPGPFPGIIDLFGVGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKSIETMHMEYFEEAVNYLRSHPEVKGPGIGLLGISKGGELGLAMASFLKG-ITAAVVINGSVAAVGNTISYKDETIPPVSLLRNQVKMTKDGLLDVVEALQSPL--VDKKSFIPVERSDTTFLFLVGQDDHNWKSEFYADEISKRLQAHGKEKPQIICYPAAGHYIEPPYFPLCSAGMHLLVGANITFGGEPRAHAVAQVDAWQQLQTFFHKQLGSKS--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88267-1", "uniprot_id": "ACOT1_RAT", "id": "O88267-1", "name": "Acyl-coenzyme A thioesterase 1", "aln": "-----------------------------------------------------------------------MEATLSLEPAGRSCWDEPLSITVRGLVPEQPVTLRAALRDEKGALFRARALYRADAHGELDLARAPALGGSFTGLEPMGLIWAMEPERPFWRLVKRDVQTPFVVELEVLDGHEPDGGRLLARAVHERHFMAPGVRRVPVREGRVRATLFLPPEPGPFPGIIDLFGVGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKTMETMRIEYFEEAVNYLRGHPEVKGPGIGLLGISKGGELGLAMASFLKG-ITAAVVINGSVAAVGNTICYKDETIPPVTILRNQVKMTKDGLKDVVDALQSPL--VEQKSFIPVERSDTTFLFLVGQDDHNWKSEFYANEISKRLQAHGKEKPQIICYPEAGHYIEPPYFPLCSAGMHLLVGANITFGGEPKPHSVAQLDAWQQLQTFFHKQLGGKSHGVSPKI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55137-1", "uniprot_id": "ACOT1_MOUSE", "id": "O55137-1", "name": "Acyl-coenzyme A thioesterase 1", "aln": "-----------------------------------------------------------------------MEATLNLEPSGRSCWDEPLSIAVRGLAPEQPVTLRSVLRDEKGALFRAHARYRADSHGELDLARTPALGGSFSGLEPMGLLWAMEPDRPFWRLVKRDVQTPFVVELEVLDGHEPDGGQRLAHAVHERHFLAPGVRRVPVREGRVRATLFLPPEPGPFPGIIDLFGVGGGLLEYRASLLAGKGFAVMALAYYNYDDLPKNMETMHMEYFEEAVNYLRSHPEVKGPGIGLLGISKGGELGLAMASFLKG-ITAAVVINGSVAAVGNTISYKDETIPPVTILRNQVKMTKDGLKDVVDALQSPL--VDKKSFIPVERSDTTFLFLVGQDDHNWKSEFYADEISKRLQAHGKEKPQIICYPAAGHYIEPPYFPLCSAGMHLLVGANITFGGEPKPHAMAQLDAWQQLQTFFHKQLGSECLHVSPKI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86TX2-1", "uniprot_id": "ACOT1_HUMAN", "id": "Q86TX2-1", "name": "Acyl-coenzyme A thioesterase 1", "aln": "-----------------------------------------------------------------------MAATLILEPAGRCCWDEPVRIAVRGLAPEQPVTLRASLRDEKGALFQAHARYRADTLGELDLERAPALGGSFAGLEPMGLLWALEPEKPLVRLVKRDVRTPLAVELEVLDGHDPDPGRLLCRVRHERYFLPPGVRREPVRAGRVRGTLFLPPEPGPFPGIVDMFGTGGGLLEYRASLLAGKGFAVMALAYYNYEDLPKTMETLHLEYFEEAVNYLLSHPEVKGPGVGLLGISKGGELCLSMASFLKG-ITAAVVINGSVANVGGTLRYKGETLPPVGVNRNRIKVTKDGYADIVDVLNSPLEGPDQKSFIPVERAESTFLFLVGQDDHNWKSEFYANEACKRLQAHGRRKPQIICYPETGHYIEPPYFPLCRASLHALVGSPIIWGGEPRAHAMAQVDAWKQLQTFFHKHLGGHEGTIPSKV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P49753-1", "uniprot_id": "ACOT2_HUMAN", "id": "P49753-1", "name": "Acyl-coenzyme A thioesterase 2, mitochondrial", "aln": "-----MSNKLLSPHPHSVVLRSEFKMASSPAVLRASR----LYQWSLKSSAQFLGSPQLRQVGQIIRVPARMAATLILEPAGRCCWDEPVRIAVRGLAPEQPVTLRASLRDEKGALFQAHARYRADTLGELDLERAPALGGSFAGLEPMGLLWALEPEKPLVRLVKRDVRTPLAVELEVLDGHDPDPGRLLCQTRHERYFLPPGVRREPVRVGRVRGTLFLPPEPGPFPGIVDMFGTGGGLLEYRASLLAGKGFAVMALAYYNYEDLPKTMETLHLEYFEEAMNYLLSHPEVKGPGVGLLGISKGGELCLSMASFLKG-ITAAVVINGSVANVGGTLHYKGETLPPVGVNRNRIKVTKDGYADIVDVLNSPLEGPDQKSFIPVERAESTFLFLVGQDDHNWKSEFYANEACKRLQAHGRRKPQIICYPETGHYIEPPYFPLCRASLHALVGSPIIWGGEPRAHAMAQVDAWKQLQTFFHKHLGGHEGTIPSKV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2K4M8-1", "uniprot_id": "A0A0G2K4M8_RAT", "id": "A0A0G2K4M8-1", "name": "", "aln": "MWTGAESSTLALPHCYSDFPDHPTVLVLSRGAHESETPRDALGRLHSRSGSAPNSGRALPGHPTPTPPSLLMEARLTLEPTGRSCWDEPLRITVRGLAPEQPVTLCSSLRDEKGALFRAHALYRADAHGELDLARAPALGGSFTGLEPMGLIWAMEPERPFWRLIKRDVQTPFVVELEVLDGHEPDGRRLLARTVHERHFMAPGVRRVPVREGRVRTTLFLPPGNGPFPGIINLFGVGGGLLEYRASLLAGKGFAVMALAYY-YKDLPKDMDIIRLEYFEEAVSYQLRHPQVKGPGIGLLGISKGAELCLSMASFLNG-ITAAVIINGSMVNVAGTLYYKEESLPASSMNLERIRVTKDGFKDVIDILTVPPEGPDQKSIIPVERSNTTFLFLVGQDDRNWKSEFYAREASKRLQAHGKEKPQIIFYPETGHYIEPPYFPLCKASTHFFFFFFLVL--------------------FFG---AGDRTQGLALPR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6Q2Z6-1", "uniprot_id": "ACOT5_MOUSE", "id": "Q6Q2Z6-1", "name": "Acyl-coenzyme A thioesterase 5", "aln": "-----------------------------------------------------------------------MVPTVSLEPTGHSCWDEPLSIAVRGLAPEQPVTLRTALRDEKGALFRAHARYRADSHGELDLARTPALGGSFSGLEPMGLLWAMEPDRPFWRLIKRDVQTPFVVELEVLDGHEPDGGRLLARAVHERHFMAPGVRRVPVREGRVRATLFLPPGTGPFPGIIDLFGVGGGLLEYRASLLAGKGFAVMALAYYKYDDLPKVIDILHLEYFEEAVTYLLSHPQVKGPGVGLLGISKGAELSLSMASFLKG-ITAAVVINGATVNVISTLYYKEESLPGLGMHLERIKVTKDGFKDIIDILNVPLEAPDQKSLIPLERSDTAFLFLVGQDDHNWKSEFYAREASKRLQAHGKEKPQIVCYPKTGHHIEPPYIPWSIAAPHSYFDKPILLGGEPRAHAMAQVDAWQRLQTFFHKHLSGDKRPSPAKL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZIQ1-1", "uniprot_id": "D3ZIQ1_RAT", "id": "D3ZIQ1-1", "name": "", "aln": "-MGVERSRILWPESRIKAQPRSQTSDLSVPKLLTDFGASLVWVLETHQVGSTAGQALLRTPRGALVSFQLPMAATLSLEPAGRSCWDEPLSITVRGLAPEQPVTLRAALRDEKGALFRAHARYHADSHGMLDLARAPALGGSFAGLEPMGLLWAMEPERPFWRLIKRDVQTPFVVELEVLDGHEPDGGQRLARAVHERHFMAPGVRRVPVREGRVRATLFLPPGQGPFPGIIDVYGVGGGLLEYRASLLAGHGFATLALAFYGFEDLPKEFNVIEVDYFEEAVCYMLQHPKVKGPDIGLLGLSLGADVCLIMASFLKN-VSATVSINGSAFSGNRYIHYKQTMIPPLGHDLRRTKVAFSGILDIVDIRNDAVGGCENPSMIPIEKAKGPILFVAGQDDHCWRSELYTQIASERLQAHGKERPQIISYPGTGHYIEPPYFPMCPASLHKIVNKAVVWGGEVRAHSKAQIDAWKQILSFFGKHLDSTHNRASCRL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BWN8-1", "uniprot_id": "ACOT4_MOUSE", "id": "Q8BWN8-1", "name": "Peroxisomal succinyl-coenzyme A thioesterase", "aln": "-----------------------------------------------------------------------MAATLSVEPTGRSCWDEPLSIAVRGLAPEQPVTLRSVLRDEKGALFRAHARYRADSHGELDLARVPALGGSFSGLEPMGLLWAMEPDRPFWRLIKRDVQTPFLVELEVLDGHEPDGGRRLARTVHERHFMAPGVRRVPVREGRVRATLFLPPGQGPFPGIIDVYGVGGGLLEYRAGLVAGHGFATLALAFYDFEDLPKELNVIEVDYFEEAVRYMLRHPKVKGPDIGLLGLSLGADVCLIMASFLNN-VSATVSINGSAFSGNRHIKYKQTMIPPLGHDLRRMKVAFSGILDIVDIRNDAVGGCENPSMIPIEKAKGPILFVAGQDDHCWRSELYTQIASDRLQAHGKERPQVLSYPGTGHYIEPPYFPMCPASLHKIVNEAVIWGGEVKAHSKAQIDAWKQILFFFGKHLGSTHSRASCRL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N9L9-1", "uniprot_id": "ACOT4_HUMAN", "id": "Q8N9L9-1", "name": "Peroxisomal succinyl-coenzyme A thioesterase", "aln": "-----------------------------------------------------------------------MSATLILEPPGRCCWNEPVRIAVRGLAPEQRVTLRASLRDEKGALFRAHARYCADARGELDLERAPALGGSFAGLEPMGLLWALEPEKPFWRFLKRDVQIPFVVELEVLDGHDPEPGRLLCQAQHERHFLPPGVRRQSVRAGRVRATLFLPPGPGPFPGIIDIFGIGGGLLEYRASLLAGHGFATLALAYYNFEDLPNNMDNISLEYFEEAVCYMLQHPQVKGPGIGLLGISLGADICLSMASFLKN-VSATVSINGSGISGNTAINYKHSSIPPLGYDLRRIKVAFSGLVDIVDIRNALVGGYKNPSMIPIEKAQGPILLIVGQDDHNWRSELYAQTVSERLQAHGKEKPQIICYPGTGHYIEPPYFPLCPASLHRLLNKHVIWGGEPRAHSKAQEDAWKQILAFFCKHLGGTQKTAVPKL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q32Q92-1", "uniprot_id": "ACOT6_MOUSE", "id": "Q32Q92-1", "name": "Acyl-coenzyme A thioesterase 6", "aln": "-----------------------------------------------------------------------MAATLSVEPAGRSCWDEPLSIAVRGLAPEQPVTLRSVLRDEKGMLFRAHARYRADSHGELDLARTPALGGSFSGLEPMGLLWAMEPDRPFWRLIKRDVQIPFVVELEVLDGHEPDGGQRLARAVHERHFMAPGVRRVPVREGRVRATLFLPPGKGQFPGIIDLYGSIGGLCEHRASLLAGHGFAVLALAYFQFEDLPENLSDVRLEYFEEALALMLRHPQVKGPNIGLIGVSKGADLCLSMAAFLKDNITATVLINACVANTLVPLYYKDLFVPELGCDQTK---NKSGLMDLRDMWNNPLEEPNHQSLIPLEKAQGPFLFLVGMDDHNWKSDVYARIACERLQAHGKDRPQIIYYPETGHCIEPPYFPPPIATVHFVLGEAVFNGGKPRAQSRAQLDAWQRIQTFFQKYLNGEKPARHSKL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3I5F7-1", "uniprot_id": "ACOT6_HUMAN", "id": "Q3I5F7-1", "name": "Acyl-coenzyme A thioesterase 6", "aln": "-----------------------------------------------------------------------MAATLILEPAGRCCWDEPLRIAVRGLAPEQPVTLRTSLRDEEGALFRAHARYRADARDELDLERAPALGGSFAGLQPMGLLWALEPEKALVRLVKRDVRTPFAVELEVLDGHDTEPGRLLCLAQNKRDFLRPGVRREPVRAGPVRAALFLPPDEGPFPGIIDLFGSSRGLCEYRASLLAGHGFAVLALAYFRFEDLPEDLNDVHLEYFEEAVDFMLQHPKVKGPSIALLGFSKGGDLCLSMASFLKG-ITATVLINACVANTVAPLHYKDMIIPKLVDDLGKVKITKSGFLTFMDTWSNPLEEHNHQSLVPLEKAQVPFLFIVGMDDQSWKSEFYAQIASERLQAHGKERPQIICYPETGHCIDPPYFPPSRASVHAVLGEAIFYGGEPKAHSKAQVDAWQQIQTFFHKHLNGKKSVKHSKI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NZE7-1", "uniprot_id": "A0A8M1NZE7_DANRE", "id": "A0A8M1NZE7-1", "name": "", "aln": "-------------------------------------------------MYAALKFAFMPFARSLAKVHYSSGVSIKLLPSYKCSFEDPVHVMVSGLNPHQRVNLRSKITDEGGRDFKASAIYLADDNGQIDLKRDSSAGGSFSGVEPMGLFWALKADLLSCKFKLKDVTRPALVDIEVVGEDE----KVLAKVTNERHCLSEGVRRSLVTEGRIRGTLFMPTGNGPFPGILDTYILKGGPFELRAALLAKRGFAVLALAYQNYQDLPKKADKFHLEYFEEGLDFLRRQPEVKGQKIGLLSISKSGDLALSMSTFLPD-ITAAVWINGCNANSLIPLYYKDMYIPPLTLDFKKKKMTALGLVDMLEVVNDPMSKEGLPTVIPIERASASFMFIASEADMNWRSVYHAKLACDRLKAHGKNNYELVKYEKAGHFIEVPYMPFCLAAFHGVLEQPVLFGGEPKAHSEAQVDAWQRIIIFFKRTLGS----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * . ::*: : * ** *.* *.* : : ** * *:* * * ** . ::* * .: ****:*::****:**::.: :: :** * *::**:. .: : *. . ::* : **** * * :* :**:*. : : * * **.*:* :***.:***: :.***: . . ::****.: :*:*.* :.::..* ..:: : *::** . ::*:* **.. : *: : : * . : :.:*:*::. .::::.. * *:* :: ..**:***: . ::: * :** *: **:* * : . : ** . ", "identical_positions": 101, "similar_positions": 121, "identity": "20.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110407-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08739-1", "uniprot_id": "AMPD3_MOUSE", "id": "O08739-1", "name": "AMP deaminase 3", "aln": "---------------------------------MPRQFPKLNMSDLDEHVR-LLAEKVFAKVLREEDSK------DVMSLFTVPEDCPIGQKEAKERELQKELAEQKSVETAKRKKSFKMIRSQ-SLSLQMPTQQDWKGPPTASPAMSPATPLVPGATSKPGPAPY-AMPEYQRVTISGDYCAGITVED----YEQAAKSLAKALMIREKYARLAYH---RFPRTTAQYLAHQ-GESVPLE---EGLPDFHP--PPLPQEDPYCLDDAPPNLGYLVRMHGGVLFVYDNQTMLERQEPHSLPYPDLETYIVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKLGRKITLRQVFDSLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEDSKYQYSEPRLSIYGRSPKEWSSLARWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPSPDLWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITALTK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O09178-1", "uniprot_id": "AMPD3_RAT", "id": "O09178-1", "name": "AMP deaminase 3", "aln": "---------------------------------MPRQFPKLNMSDLDEHVR-LLAEKVFAKVLREEDSK------DVMSLFTVPKDCPIGQKEAKERELQKELAEQKSVETAKRKKSFKMIRSQ-SMSLQMPT-QDWKGPPSVSPAMSPTTPLVLGAASKPGLAPY-DMPEYQRATISGDYCAGITMED----YEQAAKSLAKALMIREKYARLAYH---RFPRTTAQYLAHQ-GESVPLE---EGLPDFHP--PPLPQEDPYCLDDAPPNLGYLVRMQGGVLFVYDNQTMLERQEPHSLPYPDLETYIVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKYTYQTEPDRTVAEKLGRKITLRQVFDSLHMDPYDLTVDSLDVHAGRQTFHGFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEDSKYQYSEPRLSIYGRSPKEWSSLARWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPSFGKMLENIFLPLFQATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPSPDLWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITALAD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q01432-1", "uniprot_id": "AMPD3_HUMAN", "id": "Q01432-1", "name": "AMP deaminase 3", "aln": "---------------------------------MPRQFPKLNISEVDEQVR-LLAEKVFAKVLREEDSK------DALSLFTVPEDCPIGQKEAKERELQKELAEQKSVETAKRKKSFKMIRSQ-SLSLQMPPQQDWKGPPAASPAMSPTTPVVTGATSLPTPAPY-AMPEFQRVTISGDYCAGITLED----YEQAAKSLAKALMIREKYARLAYH---RFPRITSQYLGHPRADTAPPE---EGLPDFHP--PPLPQEDPYCLDDAPPNLDYLVHMQGGILFVYDNKKMLEHQEPHSLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPNPDVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITALTN-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BBF1-1", "uniprot_id": "A0A8M3BBF1_DANRE", "id": "A0A8M3BBF1-1", "name": "AMP deaminase", "aln": "---MQPGLSTQEMMRRLQTPIAKQLSSPCLGKDMPRQFPKIALTDVDEEVR-LLAEKVYASALKEEDTK------DALSMYTVPEDCPIGLQEAKQRELLRELAEQQSEESAKRKKSFKMIRSQ-SMSLQIPL--------STESVRGVVTPLITPSSTCSSISP--NFPEYQRVTISGDYCAGITVED----YEQAAKSLLKALFIREKYSKLAYH---RFPRTTAQFLRNAANEKWTEED--EILPDICP--CPGEGEDPYSMENVPENLNYQMKMKDGIIYVYENAEALSMNKPRCLPYPDLETFAIDMSHVLAMIADGPTKTYCHRRLNFLGSKFYLHEMLNEMAELKELKGVPHRDFYNVRKVDTHIHAAACMNQKHLLDFIQTTYKTDAERVVLEKAGLKLTLKQVFNNLNMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELREIYLKADNYINGEYFARLIKEVAHNLEESKYQHAEPRLSIYGRSPEEWESLSHWFIQNKVYSPNMRWIIQVPRIYDIFRSRKLVPNFAKMLENVFLPLFEATVNPQKHKELHVFLKYVTGFDSVDDESKHSDHMFSYKSPKPEQWTTDDNPPYSYYLFHMYANIMVLNNLRKERGLSTFQFRPHCGEAGSITHLVSAFLTADNISHGLNLKKSPVLQYLYYLAQVPIAMSPLSNNSLFLEYSKNPLREFLHKGLCVSLSTDDPMQFHYTKEALMEEYAIAAQLWKLSTCDVCEIARNSVLQSGLSHEEKKHFLGVSYLKDGPEGNDIRRTNVAQIRMAYRHETLCNELSFLVDAVKSEVVGLL---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JEY5-1", "uniprot_id": "X2JEY5_DROME", "id": "X2JEY5-1", "name": "AMP deaminase", "aln": "-------------MSYRGMLSTSDGSPVELRVQDVDSFDGSMMSHAATNAAGPLGSKASGKSLNACTSMSMPQKPSSLRATCDLADSPVDEKAEADVEVTNEISAPYEVPQFPIEQIEKKLQIQRHLNEKQATGPRPVATAAVLATNRESSSSTEGRESAVTMERNDADINFQRVSISGEDTSGVPLED----LERASTLLIEALRLRSHYMAMSDQ---SFPSTTARFLKTVKLKDRINNLPVKEVSDVHLRHSPMKITNPWNVE-FPNDEDFKIKPLNGVFHIYEND---DESSEIKYEYPDMSQFVNDMQVMCNMIADGPLKSFCYRRLCYLSSKYQMHVLLNELRELAAQKAVPHRDFYNTRKVDTHIHAASCMNQKHLLRFIKKTLKNNANEVVTVTNGQQMTLAQVFQSMNLTTYDLTVDMLDVHADRNTFHRFDKFNSKYNPIGESRLREVFLKTDNYLNGKYFAQIIKEVAFDLEESKYQNAELRLSIYGKSPDEWYKLAKWAIDNDVYSSNIRWLIQIPRLFDIFKSNKMMKSFQEILNNIFLPLFEATARPSKHPELHRFLQYVIGFDSVDDESKPENPLFDNDVPRPEEWTYEENPPYAYYIYYMYANMTVLNKFRQSRNMNTFVLRPHCGEAGPVQHLVCGFLMAENISHGLLLRKVPVLQYLYYLTQIGIAMSPLSNNSLFLNYHRNPLPEYLARGLIISLSTDDPLQFHFTKEPLMEEYSIAAQVWKLSSCDMCELARNSVMMSGFPHAIKQQWLGPIYYEDGIMGNDITRTNVPEIRVAYRYETLLDELSNIFKVNQTCSIADMNAT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P15274-1", "uniprot_id": "AMPD_YEAST", "id": "P15274-1", "name": "AMP deaminase", "aln": "MDNQATQRLNDLSLEPAPSHDEQDGSGLVIDIDQRKIGDEQAGVVVDDETP-PLEQQDSHESLAADSRNAN----FSYHENQQLLENGTKQLALDEHDSHSAILEQPSHSTNCSSSNIAAMNKGHDSADHASQNSGGKPRTLSASAQHILPETLKSFAGAPVVNKQVRTSASYKMGMLADDASQQFLDDPSSELIDLYSKVAECRNLRAKYQTISVQNDDQNPKNKPGWVVYPPPPKPSYNSDTKTVVPVTNK-PDAEVFDFTKCEIPGEDPDWEFTLNDDDSYVVHRS---GKTDELIAQIPTLRDYYLDLEKMISISSDGPAKSFAYRRLQYLEARWNLYYLLNEYQETSVSKRNPHRDFYNVRKVDTHVHHSACMNQKHLLRFIKHKLRHSKDEKVIFRDGKLLTLDEVFRSLHLTGYDLSIDTLDMHAHKDTFHRFDKFNLKYNPIGESRLREIFLKTNNYIKGTYLADITKQVIFDLENSKYQNCEYRISVYGRSLDEWDKLASWVIDNKVISHNVRWLVQIPRLYDIYKKTGIVQSFQDICKNLFQPLFEVTKNPQSHPKLHVFLQRVIGFDSVDDESK-VDRRFHRKYPKPSLWEAPQNPPYSYYLYYLYSNVASLNQWRAKRGFNTLVLRPHCGEAGDPEHLVSAYLLAHGISHGILLRKVPFVQYLYYLDQVGIAMSPLSNNALFLTYDKNPFPRYFKRGLNVSLSTDDPLQFSYTREPLIEEYSVAAQIYKLSNVDMCELARNSVLQSGWEAQIKKHWIGKDFDKSGVEGNDVVRTNVPDIRINYRYDTLSTELELVNHFANFKRTIEEK--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. * .: . * : : : : . .. :. : . .. . : : .: : ::* . : :. :* :* :: : * .. :: : : : . : : : .: . .. .: .. . * : : *:. : : :*** *::.:*** :* ::: :: :*** * * *******.******:* ::******** **: . : . :. * * :** :** .::: ***::* **:** ::*** ***** ****:* *.**:::**::**: * *:* : *:* :**:**** .* *:*:**:* .** .*: * *::.* * *:**::*:**::**::. :: .* .: :*:* ***:.* .*..* :** **: * ********** : * . * *. * :****:**::::*:*: **: * .*.:.*: :******** ***..:* *..****: *:* *.:****** *: *********:*** * :**: .:: :** :*******:** :*:*.*:***::***::***. *:**:*****: ** *::::* : :.* ***: :***.:**: :*::** **. : . : ", "identical_positions": 243, "similar_positions": 209, "identity": "29.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110407-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P09803-1", "uniprot_id": "CADH1_MOUSE", "id": "P09803-1", "name": "Cadherin-1", "aln": "-------------MGARCRSFSALLLLLQVSSWLCQELEPES--CSPGFS-SEVYTFPVPERHLERGHVLGRVRFEGCTGRPRTAFFSEDSRFKVATDGTITVKRHLKLHKLETSFLVRARDSSHRELSTKVTLKSMGHHHHRHHHRDPASESNPELLMFPSVYPGLRRQKRDWVIPPISCPENEKGEFPKNLVQIKSNRD--KETKVFYSITGQGADKPPVGVFIIERETGWLKVTQPLDREAIAKYILYSHAVSSNGEAVEDPMEIVITVTDQNDNRPEFTQEVFEGSVAEGAVPGTSVMKVSATDADDDVNTYNAAIAYTIVSQDPELPHKNMFTVNRDTGVISVLTSGLDRESYPTYTLVVQAADLQGEGLSTTAKAVITVKDINDNAPVFNPSTYQGQVPENEVNARIATLKVTDDDAPNTPAWKAVYTVVNDPD-QQFVVVTDPTTNDGILKTAKGLDFEAKQQYILHVRVENEEPFEGSLVPSTATVTVDVVDVNEAPIFMPAERRVEVPEDFGVGQEITSYTAREPDTFMDQKITYRIWRDTANWLEINPETGAIFTRAEMDREDAEHVKNSTYVALIIATDDGSP-IATGTGTLLLVLLDVNDNAPIPEPRNMQFCQRNPQPHIITILDPDLPPNTSPFTAELTHGASVNWTIEYNDAAQESLILQPRKDLEIGEYKIHLKLADNQNKDQVTTLDVHVCDCEG--TVNNCMKAGIVAAGLQVPAILGILGGILALLILILLLLLFLRRRTV-VKEPLLPPDDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTR-NDVAPTLMSVPQYRPRPANPDEIGNFIDENLKAADSDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDQDQDYDYLNEWGNRFKKLADMYGGGEDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9R0T4-1", "uniprot_id": "CADH1_RAT", "id": "Q9R0T4-1", "name": "Cadherin-1", "aln": "-------------MGARCRSFSALLLLLQVSSWLCQQPESESDSCRPGFS-SEVYTFLVPERHLERGHILGRVKFEGCTGRPRTAFFSEDSRFKVSTDGVITVKRHLKLHKLETSFLVHAWDSSYRKLSTKVTLKSLGHHHHRHHHRDPVSESNPELLTFPSFHQGLRRQKRDWVIPPINCPENQKGEFPQRLVQIKSNRD--KETTVFYSITGPGADKPPVGVFIIERETGWLKVTQPLDREAIDKYLLYSHAVSSNGEAVEDPMEIVVTVTDQNDNRPEFIQEVFEGSVAEGALPGTSVMQVSATDADDDINTYNAAIAYTILSQDPELPHKNMFTVNRDTGVISVVTSGLDRESYPTYTLVVQAADLQGEGLSTTAKAVITVKDINDNAPIFNPSTYQGQVLENEVGARIATLKVTDDDAPNTPAWNAVYTVVNDPD-HQFTVITDPKTNEGILKTAKGLDFEAKQQYILHVTVENEEPFEGSLVPSTATVTVDVVDVNEAPIFVPAEKRVEVPEDFGVGLEIASYTAREPDTFMEQKITYRIWRDTANWLEINPETGVISTRAEMDREDSEHVKNSTYTALIIATDDGSP-IATGTGTLLLVLSDVNDNAPIPEPRNMQFCQRNPKPHVITILDPDLPPNTSPFTAELTHGASVNWTIEYNDAEQESLILQPRKDLEIGEYKINLKLSDNQNKDQVTTLEVHVCDCEG--TVNNCMKAISLEAGLQVPAILGILGGILALLILILLLLLFLRRRTV-VKEPLLPPDDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVIR-NDVAPTLMSMPQYRPRPANPDEIGNFIDENLKAADSDPTAPPYDSLLVFDYEGSGSEAASLSSLNSSESDQDQDYDYLNEWGNRFKKLADMYGGGEED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0ABK0LL01-1", "uniprot_id": "A0ABK0LL01_RAT", "id": "A0ABK0LL01-1", "name": "", "aln": "MHRGTLWCNYILGIVCLEG-RMLGSHLHQV----CWLRSVVSESYREDFIREAGVTLEVGGTDLEPSQALEKEALAG------HEVLGADS------GGIITLN--------------------------------------RETVQGGKGVMNS------PPSRILRRRKREWVMPPISVPENGKGPFPQRLNQLKSNKD--RGTKLFYSITGPGADSPPEGVFTIEKETGWLLLNMPLDREKIVKYELFGHAVSENGASVEEPMNISIIVTDQNDNKPKFTQDTFRGSVPEGVMPGTSVMQVTATDEDDAINTYNGVVAYSIHSQEPKEPHDLMFTIHKSTGTISVISSGLDREKVPEYTLTIQATDMDGDGSTTTAEAVVQILDTNDNAPEFQPQKYEAWVPENAVGHEVQRLTVTDLDSPNSPAWRATYHIVGGDDGDHFTVATHPETNQGILTTKKGLDFEAQNQHTLYIEVTNEASFAVKLPTATATVVVHVEDVNEAPVFVPPSKVIEAQEGISIGELVCVYTAQDPDK-EEQKISYSILRDPASWLAVDPDSGQITAAGILDREDEQFVKNDIYEVMVLATDNGNP-PTTGTGTLLLTLTDINDHGPIPEPRQIIICNQSPVPQVLNITDKDLSPNSSPFQAQLTHDSDIYWMAEVSEKG-DTVALSLKKFLKQDTYDLHLSLSDHGNREQLTMIRATVCDCHG--QVLNDCPRPWKGG-----FILPVLGAVLALLTLLLALLLLVRKKRK-VKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDITQLHRGLEARPEVVLRNDVAPTFIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDSLLVFDYEGSGSDAASLSSLTSSTSDQDQDYNYLTEWGSRFKKLADMYGGGEDD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10287-1", "uniprot_id": "CADH3_MOUSE", "id": "P10287-1", "name": "Cadherin-3", "aln": "-------------MELLSGPHAFLLLLLQV----CWLRSVVSEPYRAGFIGEAGVTLEVEGTDLEPSQVLGKVALAG------QGMHHADN------GDIIMLT--------------------------------------RGTVQGGKDAMHS------PPTRILRRRKREWVMPPIFVPENGKGPFPQRLNQLKSNKD--RGTKIFYSITGPGADSPPEGVFTIEKESGWLLLHMPLDREKIVKYELYGHAVSENGASVEEPMNISIIVTDQNDNKPKFTQDTFRGSVLEGVMPGTSVMQVTATDEDDAVNTYNGVVAYSIHSQEPKEPHDLMFTIHKSTGTISVISSGLDREKVPEYRLTVQATDMDGEGSTTTAEAVVQILDANDNAPEFEPQKYEAWVPENEVGHEVQRLTVTDLDVPNSPAWRATYHIVGGDDGDHFTITTHPETNQGVLTTKKGLDFEAQDQHTLYVEVTNEAPFAVKLPTATATVVVHVKDVNEAPVFVPPSKVIEAQEGISIGELVCIYTAQDPDK-EDQKISYTISRDPANWLAVDPDSGQITAAGILDREDEQFVKNNVYEVMVLATDSGNP-PTTGTGTLLLTLTDINDHGPIPEPRQIIICNQSPVPQVLNITDKDLSPNSSPFQAQLTHDSDIYWMAEVSEKG-DTVALSLKKFLKQDTYDLHLSLSDHGNREQLTMIRATVCDCHG--QVFNDCPRPWKGG-----FILPILGAVLALLTLLLALLLLVRKKRK-VKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDITQLHRGLEARPEVVLRNDVVPTFIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDSLLVFDYEGSGSDAASLSSLTTSASDQDQDYNYLNEWGSRFKKLADMYGGGEDD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22223-1", "uniprot_id": "CADH3_HUMAN", "id": "P22223-1", "name": "Cadherin-3", "aln": "-------------MGLPRG-PLASLLLLQV----CWLQCAASEPCRAVFR-EAEVTLEAGGAEQEPGQALGKVFMGCPG--QEPALFSTDN------DDFTVRN--------------------------------------GETVQERRSLKERNPLKIFPSKRILRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKD--RDTKIFYSITGPGADSPPEGVFAVEKETGWLLLNKPLDREEIAKYELFGHAVSENGASVEDPMNISIIVTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIHSQEPKDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDGDGSTTTAVAVVEILDANDNAPMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFTITTHPESNQGILTTRKGLDFEAKNQHTLYVEVTNEAPFVLKLPTSTATIVVHVEDVNEAPVFVPPSKVVEVQEGIPTGEPVCVYTAEDPDK-ENQKISYRILRDPAGWLAMDPDSGQVTAVGTLDREDEQFVRNNIYEVMVLAMDNGSP-PTTGTGTLLLTLIDVNDHGPVPEPRQITICNQSPVRQVLNITDKDLSPHTSPFQAQLTDDSDIYWTAEVNEEG-DTVVLSLKKFLKQDTYDVHLSLSDHGNKEQLTVIRATVCDCHG--HVET-CPGPWKGG-----FILPVLGAVLALLFLLLVLLLLVRKKRK-IKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDITQLHRGLEARPEVVLRNDVAPTIIPTPMYRPRPANPDEIGNFIIENLKAANTDPTAPPYDTLLVFDYEGSGSDAASLSSLTSSASDQDQDYDYLNEWGSRFKKLADMYGGGEDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G176-1", "uniprot_id": "A0AC58G176_DANRE", "id": "A0AC58G176-1", "name": "Cadherin-1", "aln": "-------------MRLCCLFGKSLPAVLDIYLLFARVMEAIGAVWSGTLIVLFQGVSYVFAEETLLHAEKSTVNFSYGSARDEEVYSNEGN------HMDIIVN-------------------------------------------SPPQFSNLLVEEFQSSSEGRRRRKREWAIPPFTVLENDKSALPKILFKLKANLDGVPDEDIRYSITGEGADQPPVGIFTVTSMSGIVKVTQQLDREKKALYLLMAHANSVKG-IKEKPTNLTIIVADQNDNRPVFVENPFNGHVSESATIGHEFMAVTATDADDPD-TFNADVRYKIVSQDPLLPNPNMFEINLVTGGIYVKFLGLDREQLSRYTLVIQAADLQGDGMMTTGTAVITVTDSNDNAPQFDETTHIVSVSENQVAAIVAKLPVIDADELGSPAWSTKYRIISGDKGGFFNVSTGPSRLEGVIMTVKPLDYEKTKQCILSVIVENDDKFVGPLPTSTATVTVNVEDVNEPPEFIPKEQIISKPEDLPVGSDVVVYTATDPDTGRLQKITYKISNDPAGWLTVNRETGLIKIRNSMDRESS-YVRDGKYRTTILALDNDDDNPATGTGTLVIKVEDVNDNAPVINEEHIQICNR-EATVLLSITDTDGPPYAAPFSISLLGDTKKNWTAEMNENK-TGILLTLNTVLEPDVYNLVLMVYDNNENHKNSSIQASVCDCKGNDIVCGRIAVMPLHG------ALGILGGFLVLLLLLLLVLLFMRRKHRSIKEPLIPEDYEIRDNIYCYDEEGGGEDDQDFDLSVLHRGLDNRPNVYR-NDICPIFLSAPQYRPRPASSEDISTFVDHNLKTADNDPTAPPYDSLLVFDYEGVGSDAGSLSSLNSSSSENDQDYDFLNEWGPRFKKLADLYGREED-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :: . . : . . . : .. . . . **:**:*.:.*: ** *. :*: * ::*:* * : ***** ***.** *:* : :* : : **** * * .** * :* *.* :: : *:****::* * :: *.* * *.. * ..* *:*** ** *:*. : *.* **:* *: ** :: ** * * *****. . * *.:**:*::*:* **. **: : * ***** *: .: * ** * : * * * * .:*** : * ::.. . * : * * :*:: * * **:* .* * : * *: * * .:***:.*.* ****.* *:* .: :. *.: * : *** :**. ***:* * .*.*.** :: ::* : :***. .*::. * . ::* *... :******:: : *:**:.*: : .:: :*:: ::.* * * .* ::** .* .:. * * .: : * .. *: . *.: * : *: :..: : : . ****.* * . * :**..*.** *:* :**::*:: :****: : : ***:: *.******:***:*:: *****: **:* **: * ::. * ******..::*..*: .***:*:.********:******** **:*.*****.:* *::****::*.*** *******:** *: ", "identical_positions": 286, "similar_positions": 223, "identity": "31.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110407-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P31211-1", "uniprot_id": "CBG_RAT", "id": "P31211-1", "name": "Corticosteroid-binding globulin", "aln": "---------------------------------MSLALYTCLLWLCTSGLW---TAQASTN---------ESSNSHRGLAPTNVDFAFNLYQRLVAL--NPDKNTLISPVSISMALAMVSLGS---AQTQSLQSLGFNLTE-TSEAEIHQSFQYLNYLLKQSDTGLEMNMGNAMFLLQKLKLKDSFLADVKQYYESEALAIDFEDWTKASQQINQHVKDKTQGKIEHVFS--DLDSPASFILVNYIFLRGIWELPFSPENTRE-EDFYVNETSTVKVPMMVQS-GSIGYFRDSVFPCQLIQMDYVG----------------NGTAFFILPD----QGQMDTVIAALSRDTIDRWGKLMTP----RQVNLYIPKFSISDTYDLK-DMLEDLNIKDLLTNQSDFSG-NTKDVPLTLT-MVHKAMLQLDEGNVLPNSTNGAPLHLRSEP----LDIKFNKPFILLLFDKFTWSSLMMSQVVNPA------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q06770-1", "uniprot_id": "CBG_MOUSE", "id": "Q06770-1", "name": "Corticosteroid-binding globulin", "aln": "---------------------------------MSLALYTCLFWLCTSGLW---TTQAVTD---------EDSSSHRDLAPTNVDFAFNLYKRLVAL--NSDKNTLISPVSISMALAMLSLSTR--GSTQYLENLGFNMSK-MSEAEIHQGFQYLNSLLQQSDTGLEMNMGNVMFLLQNLKLKDSFLADTKHYYESEALTIPSKDWTKAGEQINNHVKNKTQGKIEHVVS--DLDSSATLILINYIFLKGIWKLPFSPENTRE-EDFYVNETSTVKVPMMVQS-GNISYFRDSAIPCQMVQMNYVG----------------NGTTFIILPD----QGQMDTVVAALNRDTIDRWGKLMIP----RQMNLYIPKFSMSDTYDLQ-DVLADVGIKDLFTNQSDFAD-TTKDTPLTLT-VLHKAMLQLDEGNVLPAATNGPPVHLPSES----FTLKYNRPFIFLAFDKYTWSSLMMSQVMNPA------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08185-1", "uniprot_id": "CBG_HUMAN", "id": "P08185-1", "name": "Corticosteroid-binding globulin", "aln": "---------------------------------MPLLLYTCLLWLPTSGLW---TVQAMDPN----AAYVNMSNHHRGLASANVDFAFSLYKHLVAL--SPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLTE-RSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAMNFQDWATASRQINSYVKNKTQGKIVDLFS--GLDSPAILVLVNYIFFKGTWTQPFDLASTRE-ENFYVDETTVVKVPMMLQS-STISYLHDSELPCQLVQMNYVG----------------NGTVFFILPD----KGKMNTVIAALSRDTINRWSAGLTS----SQVDLYIPKVTISGVYDLG-DVLEEMGIADLFTNQANFSR-ITQDAQLKSSKVVHKAVLQLNEEGVDTAGSTGVTLNLTSKP----IILRFNQPFIIMIFDHFTWSSLFLARVMNPV------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5M8C3-1", "uniprot_id": "Q5M8C3_RAT", "id": "Q5M8C3-1", "name": "", "aln": "----------------------------MHYTRCLLLLLAGLLELSHSQPD---QEEPDNTTNQTYRQFSQQNISSYQIASGNANFAFRLYHLIASQ--NSEKNIFFSPLSISVSLAILSTGAGGDTQAQILEGLGFNLTK-LSLPEIHEGFRSLQHTIARPFTEPQISVGSALILSQNLQILSEFVSAIETSYNSKVLHANFRDKEAAVQLINNYVKQNTQGKIKNLVS--DLSPDVKMVLVNYIFFQGLWKKPFPSSRVST-SDFYVDENTVVKIPMMLQDKEDHWYLEDRRVPCTVLRMDYRG----------------DAVAFFILPD----QGKMNEVEQVLSPGMLLRWKRLLQNRFFYRKLILQLPKFSISNSYELD-EILPDLGFQDLFTPNANFSN-ISKKEKLYLSKVFHKTVLDVNEVGTKAAAATGSFATFFSAQPKK-RYLIFNRPFLVILYSTSSQDILFMGKVVNPTA-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P05544-1", "uniprot_id": "SPA3L_RAT", "id": "P05544-1", "name": "Serine protease inhibitor A3L", "aln": "---------------------------MAFIAALG-LLMAGICPAVL--C----DGTLGRDTLSHEDHGKGRQLHSLTLASSNTDFALSLYKKLALR--NPDKNVVFSPLSISAALTILSLGAKDSTMEEILEGLKFNLTE-ITEEEIHQGFGHLLQRLSQPEDQVEINTGSALFIDKEQPILSEFQEKTRALYQAEAFIADFKQPNEAKKLINDYVSNQTQGKIAELFS--DLEERTSMVLVNYLLFKGKWKVPFNPNDTFE-SEFYLDEKRSVKVPMMKIKEVTTPYVRDEELSCSVLELKYTG----------------NASALFILPD----QGKMQQVESSLQPETLKKWKDSLIP---RIINDLRMPKFSISTDYSLK-EVLPELGIKKVFSQQADLSR-ITGTKDLYVSQVVHKAVLDVDETGTEATAATGVATVIRRQ-PRT---LNFNRPFMVVITDMDSQSILFVAKITNPK------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2JSK1-1", "uniprot_id": "A0A0G2JSK1_RAT", "id": "A0A0G2JSK1-1", "name": "", "aln": "---------------------------MAFIAALG-LLMAGICPAVL--C----DGILGRDTLPHEDQGKGRQLHSLTLASINTDFTLSLYKKLALR--NPDKNVVFSPLSISAALAILSLGAKDSTMEEILEGLKFNLTE-ITEEEIHQGFGHLLQRLSQPEDQAEINTGSALFIDKEQPILSEFQEKTRALYQAEAFVADFKQCNEAKKFINDYVSNQTQGKIAELFS--DLDERTSMVLVNYLLFKGKWKVPFNPNDTFE-SEFYLDEKRSVKVPMMKIKDLTTPYVRDEELSCSVLELKYTG----------------NASALFILPD----QGKMQQVESSLQPETLKKWKDSLRP---RIISELRMPKFSISTDYNLE-EVLPELGIRKIFSQQADLSR-ITGTKNLHVSQVVHKAVLDVDETGTEGAAATAVTAALKSL-PQTVPLLNFNRPFMLVITDNNGQSVFFMGKVTNPM------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q63556-1", "uniprot_id": "SPA3M_RAT", "id": "Q63556-1", "name": "Serine protease inhibitor A3M", "aln": "----------------------------------F-LLMAGICPAVLGFP----DGTLGNDTLLHKDQDKGTQLDSLTLESINTDFAFSLYKMLALK--NPDKNVVFSPLSISAALAIVSLGAKGNTLEEILEVLRFNLTE-SYETDIHQGFGHLLQRLSQPGDQVKIITGNALFIDKNLQVLAEFQEKTRALYQVEAFTASFQQPRVTEKLINDSVRNQTQGKIQELVS--GLKERTSMVLVNILLFRGKWKVPFDPDYTFE-SEFYVDEKRSVKVSMMKIEELTTPYFRDEELSCSVLELKYTG----------------NSSALFILPD----KGRMQQVEASLQPETLKKWKDSLRP---RKIDELYLPRLSISTDYSLE-EVLPELGIRDVFSQQADLSR-ITGAKDLSVSQVVHKVVLDVNETGTEAAAATGANLVPRS--GRPPMIVWFNRPFLIAVSHTHGQHILFMAKVINPVGA----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P07759-1", "uniprot_id": "SPA3K_MOUSE", "id": "P07759-1", "name": "Serine protease inhibitor A3K", "aln": "---------------------------MAFIVAMGMILMAGICPAVLCFP----DGTKEMDIVFHEHQDNGTQDDSLTLASVNTDFAFSLYKKLALK--NPDTNIVFSPLSISAALALVSLGAKGKTMEEILEGLKFNLTE-TPEADIHQGFGNLLQSLSQPEDQDQINIGNAMFIEKDLQILAEFHEKTRALYQTEAFTADFQQPTEAKNLINDYVSNQTQGMIKELIS--ELDERTLMVLVNYIYFKGKWKISFDPQDTFE-SEFYLDEKRSVKVPMMKMKLLTTRHFRDEELSCSVLELKYTG----------------NASALLILPD----QGRMQQVEASLQPETLRKWRKTLFP---SQIEELNLPKFSIASNYRLEEDVLPEMGIKEVFTEQADLSG-ITETKKLSVSQVVHKAVLDVAETGTEAAAATGVIGGIRKA-ILP--AVHFNRPFLFVIYHTSAQSILFMAKVNNPK------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q03734-1", "uniprot_id": "SPA3M_MOUSE", "id": "Q03734-1", "name": "Serine protease inhibitor A3M", "aln": "---------------------------MAFIAALG-ILMAGICPTVLCFS----DDTWGIDILLHKNQESGTPDDSLTLASINTDFAFSLYKKMALK--NPDKNIVFSPLSISAALALVSLGAKGNTLEEILEGLKFNLTE-TSEADIHQGFGHLLQRLSQPEDQDQINIGNAMFIEKDLQILAEFHEKTRALYQTEAFTADFQQPTEATKLINDYVSNQTQGMIKKLIS--ELDDRTLMVLVNYIYFKGKWKISFDPQDTFE-SEFYLDEKRSVKVPMMKMKFLTTRHFRDEELSCSVLELKYTG----------------NASALFILPD----QGRMQQVEASLQPETLRKWWKSLKT---RKIGELYLPKFSISTDYNLK-DILPELGIKEIFSKQADLSG-ITGTKDLSVSQVVHKAVLDVAETGTEAAAATGFIFGFRSR-RLQTMTVQFNRPFLMVISHTGVQTTLFMAKVTNPK------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P29621-1", "uniprot_id": "SPA3C_MOUSE", "id": "P29621-1", "name": "Serine protease inhibitor A3C", "aln": "---------------------------MAFIVALG-LVITGICPGVLCFP----DGTLERDTLFHKDKENGTQLDSLTLASINTDFAFSLYKKLALK--NPDTNIVFSPLSISAALAIVSLGAKGNTLEEILEGLNFNLTE-TPEADIHQGFGHLLQRLSHPGEQVQISTGSALFVEKHLQILAEFQEKARALYQAEAFTADFQQPLEATKLINDYVSNQTQRKIKGLIS--DLDTDTLMVLVNYIYFKGKWKMPFNPRDTFE-SEFYLDVKRSVKVPMMKIKTLTTPYFRDEELSCTVVELKYKG----------------NASALFILPD----QGRMQQVEASLQPETLRKWKNSLRP---RKMGELYLPKFSISTDYSLK-NILPELGIKEIFSKQADLSG-ITGTKDLIVSQMVHKAVLDVAETGTEGVAATGVNFRILSR-RTS---LWFNRTFLMVISHTDVQTTLFIAKITHPKRA----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09006-1", "uniprot_id": "SPA3N_RAT", "id": "P09006-1", "name": "Serine protease inhibitor A3N", "aln": "---------------------------MTRLVTLE-LLMAGIGSALLCFP----DCILGEDTLFHEDQDKGTQLDSLTLASINTDFAFSLYKKLALR--NPDKNVVFSPLSISAALAVVSLGAKGNSMEEILEGLKFNLTE-TPETEIHRGFGHLLQRLSQPRDEIQISTGNALFIEKRLQVLAEFQEKAKALYQAEAFTADFQQSREAKKLINDYVSKQTQGKIQGLIT--NLAKKTSMVLVNYIYFKGKWKVPFDPRDTFQ-SEFYSGKRRPVKVPMMKLEDLTTPYVRDEELNCTVVELKYTG----------------NASALFILPD----QGKMQQVEASLQPETLRRWKDSLRP---SMIDELYLPKFSISADYNLE-DVLPELGIKEVFSTQADLSG-ITGDKDLMVSQVVHKAVLDVAETGTEAAAATGVKFVPMSA-KLDPLIIAFDRPFLMIISDTETAIAPFLAKIFNPK------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91WP6-1", "uniprot_id": "SPA3N_MOUSE", "id": "Q91WP6-1", "name": "Serine protease inhibitor A3N", "aln": "---------------------------MAFIAALG-LLMAGICPAVLCFP----DGTLGMDAAVQEDHDNGTQLDSLTLASINTDFAFSLYKELVLK--NPDKNIVFSPLSISAALAVMSLGAKGNTLEEILEGLKFNLTE-TSEADIHQGFGHLLQRLNQPKDQVQISTGSALFIEKRQQILTEFQEKAKTLYQAEAFTADFQQPRQAKKLINDYVRKQTQGMIKELVS--DLDKRTLMVLVNYIYFKAKWKVPFDPLDTFK-SEFYAGKRRPVIVPMMSMEDLTTPYFRDEELSCTVVELKYTG----------------NASALFILPD----QGRMQQVEASLQPETLRKWKNSLKP---RMIDELHLPKFSISTDYSLE-DVLSKLGIREVFSTQADLSA-ITGTKDLRVSQVVHKAVLDVAETGTEAAAATGVKFVPMSA-KLYPLTVYFNRPFLIMIFDTETEIAPFIAKIANPK------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q80X76-1", "uniprot_id": "SPA3F_MOUSE", "id": "Q80X76-1", "name": "Serine protease inhibitor A3F", "aln": "--------------------------------------MAGVSPAVFGCP----DVTLGRNTAVREVQENITSVDSLTLASSNTDFAFSLYKELVLK--NPDENVVFSPFSICTALALLSLGAKSNTLKEILEGLKFNLTE-TPEPDIHQGFRYLLDLLSQPGNQVQISTGSALFIEKHLQILAEFKEKARALYQAEAFTADFQQPLEATKLINDYVSNHTQGKIKELIS--DLDKRTLMVLVNYIYFKGKWEMPFDPDDTCK-SEFYLDENRSVKVPMMKINNLTTPYFRDEELSCTVVELKYTG----------------NASAMFILPD----QGKMQQVEASLQPETLRNWKDSLKP---RLINELCLPKFSISTDYSLE-HILPELGIRELFSTQADLSA-ITGTKDLRTSQVVHKAVLDVAETGTEAAAGTGYQNLQCCQGVIYSMKIYFDRPFLMIISDTNTHIALFMAKVSNPESDENFLNVEYAFPQVLEIMPEYRSVCTCCLPCLTRQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z450-1", "uniprot_id": "D3Z450_MOUSE", "id": "D3Z450-1", "name": "", "aln": "--------------------------------------MAGVSPAVLGCP----DVTLERNTAVHEVQENITSGDSLTVASSNTDFAFSLYRKLVLK--NPDENVVFSPFSIFTALALLSLGAKSNTLKEILEGLKFNLTE-TPEPDIHQGFRYLLDLLSQPGDQVQISTGSALFVEKHLQILAEFKEKARALYQAEAFTADFLQPCQAKKLINDYVSNQTQGKIKELIS--DLDKSTLMVLVNYIYFKGKWKMPFDPRDTFN-SKFYLDEKRSVKVPMMKIEELTTPYFRDDELSCSVVELKYTG----------------NASALFILPD----QGKMQQVETSLHPETLRKWKNSLKP---SRISELHLPKFSISNDYSLE-HVLPVLGIREVFSMQADLSA-ITGTMDLRVSQVVHKAVLDVTETGTEAAAATGVKVNLRCG-KIYSMTIYFKRPFLIIISDINTHIALFMAKVTNPK------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5I2A0-1", "uniprot_id": "SPA3G_MOUSE", "id": "Q5I2A0-1", "name": "Serine protease inhibitor A3G", "aln": "--------------------------------------MAGVSPAVFGCP----DVTLGRNTAVREVQENVTSVDSLTLVSSNTDFAFSLYRKLVLK--NPDENVVFSPFSICTALALLSLGAKSNTLKEILEGLKFNLTE-TPEPDIHQGFRYLLDLLSQPGNQVQISTGSALFIEKHLQILAEFKEKARALYQAEAFTADFQQPLKATKLINDYVSNHTQGKIKELIS--GLKESTLMVLVNYIYFKGKWKNPFDPNDTFK-SEFYLDEKRSVIVSMMKTGYLTTPYFRDEELSCTVVELKYTG----------------NASAMFILPD----QGRMQQVEASLQPETLRKWKNSLKP---RMIHELRLPKFSISTDYSLE-HILPELGIREVFSTQADLSA-ITGTKDLRVSQVVHKAVLDVAETGTEAAAATGMAGVGCCA-VFDFLEIFFNRPFLMIISDTKAHIALFMAKVTNPERSMNFPNGEGASSQRLESK----RLCFGDPLCLIGQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8BYY9-1", "uniprot_id": "SPA3B_MOUSE", "id": "Q8BYY9-1", "name": "Serine protease inhibitor A3B", "aln": "---------------------------MAFIAALG-LLMAEICPAVICCS----DGTLGMHNAVQKGQDTQKQLDSLTLASINTDFAFSFYKELALK--NPHKNIAFSPFGIATALNSLTLGAKGNTLEEILEVLKFNLTE-TSEADIHQGFKHLLQRLSHPGDQVQIRTGNALFVEKHLQILAEFKEKARALYHTEVFTANFQQPHEAMKLINSYMSNQTQGKIKELVS--DMDGNTSMVIVNDLFFKAEWMVPFNSDDTFM-GKFIVDRSRHVKVPMMKTKNLRTPYFRDEELKCTVVELNYKG----------------NGKAMFILPD----QGKMQQVEASLQPGTLKKWRKSLRP---RKIKELHLPKFSLSQHYNLE-DILPELGIRELFSTQADLSG-ITGVKNITVSEMIHSTELDMTEKGTEGDAITIVGYNFMSA-KLKPVFVKFEDQFLYIVLDQGDLWIHVMGKVINPSEK----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3Z451-1", "uniprot_id": "D3Z451_MOUSE", "id": "D3Z451-1", "name": "", "aln": "---------------------------MAFIAALG-LLMAGICPAVLCCP----EDTLGKHTPVQKDRDHETQLDSLTLASINTDFAFSLYKKLALK--NPHKNFVFSPLSITIALASLSLGAKGNTLEEILEGLKFNLTE-TPEADIHQGFGHLLQRLSQPGDQVQISTGNSMVVEKHLQILAEFKEKARALYHTEVFTADFQQPREARKLLNDYVSNQTQGMIKELVS--DLEERTSMVMTNFALFNGKWNMTFDPYETFM-GTFIEDRRTPVKVSMMKMKELRAPYFRDEKMKCTVVELNYKG----------------NGKAMFILPD----QGKMKQVEASLQPATLRGWRKSLRP---RMIDELYLPKFSISKNYRLE-NILPELGIKEVFSTQADLSG-ISGGKDVRVSRMFHSAALDMTETGTEARATTRDKYDFLST-KSNPTVVNLNTPFLFCVLHSDSENIDFMGKINNPAQN----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P4P1-1", "uniprot_id": "SPA3A_MOUSE", "id": "Q6P4P1-1", "name": "Serine protease inhibitor A3A", "aln": "---------------------------MAFIAALG-LLMVGICPAVTYWATA--DGQLGGHTAVQKDRDHEIQLDSVTLASINTDFAFSLYKKLALE--NPHKNIVFSPLSISAALALMSLGAKGNTLEEILEGLKFNLPE-TPEADIHQNFGHLLQMLIQPENQVQINAGNALFIDKHLQILTEFKEKARALYKAEAFTTDFQRPREATKLINDYVRKQTQGKIKELVS--DLHRNTSMALVNFLNFQGFWNVTFDPEDTFL-GNFTLDRKRTVNVPMMKTEELTTNYFRDEEMQSTVMELNYIG----------------NASFLFILPD----QGRIQHVEDSLQPQSLRKWRKSLRP---RMLDELSLPKFSLSQDYNLN-DILPELGIKEVFSTQADLSG-ITGAKNIRVSQMIHQAALDVTETHTEADVITIARYNFQSA-KIKAKIVKVDREFLYLILDPMFKSISVMGKVINPLTN----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P01011-1", "uniprot_id": "AACT_HUMAN", "id": "P01011-1", "name": "Alpha-1-antichymotrypsin", "aln": "------------------------MERMLPLLALG-LLAAGFCPAVLCHP----NSPLDEENLTQENQDRGTHVD-LGLASANVDFAFSLYKQLVLK--APDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLTE-TSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFATDFQDSAAAKKLINDYVKNGTRGKITDLIK--DLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQ-SRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVELKYTG----------------NASALFILPD----QDKMEEVEAMLLPETLKRWRDSLEF---REIGELYLPKFSISRDYNLN-DILLQLGIEEAFTSKADLSG-ITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVPTDTQNIFFMSKVTNPKQA----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q86U17-1", "uniprot_id": "SPA11_HUMAN", "id": "Q86U17-1", "name": "Serpin A11", "aln": "---------------------------MG--PAWLWLLGTGILASVHCQPLLAHGDKSLQGPQPPRHQLSEPAPAYHRITPTITNFALRLYKELAAD--APG-NIFFSPVSISTTLALLSLGAQANTSALILEGLGFNLTE-TPEADIHQGFRSLLHTLALPSPKLELKVGNSLFLDKRLKPRQHYLDSIKELYGAFAFSANFTDSVTTGRQINDYLRRQTYGQVVDCLP--EFSQDTFMVLANYIFFKAKWKHPFSRYQTQKQESFFVDERTSLQVPMMHQKEM-HRFLYDQDLACTVLQIEYRG----------------NALALLVLPD----PGKMKQVEAALQPQTLRKWGQLLLP---SLL-DLHLPRFSISGTYNLE-DILPQIGLTNILNLEADFSG-VTGQLNKTISKVSHKAMVDMSEKGTEAGAASGLLSQPPSLNTMSDPHAHFNRPFLLLLWEVTTQSLLFLGKVVNPVAG----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TPA5-1", "uniprot_id": "SPA11_RAT", "id": "Q7TPA5-1", "name": "Serpin A11", "aln": "---------------------------MG--PVWLWLLIAELLLPVHYQPSSAHGDKSLGAPQPASHQSLEPAPAYHKVTPTITNFALRLYKQLAEE--IPG-NILFSPVSLSSTVALLSLGAHADTQAQILQSLGFNLTE-TPAADIHRGFQSLLHTLDLPSPKLELKLGHSLFLDRQLKPQQRFLDSAKELYGALAFSANFTEAAATGQQINDLVRKQTYGQVVGCLP--EFDRDTLMVLLNYIFFKAKWKHPFDRYQTRKQESFFVDQRLQLRIPMMRQKEM-HRFLYDQEASCTVLQIEYSG----------------TALLLLVLPD----PGKMQQVEAALQPETLRRWGQRFLP---SLL-DLHLPRFSVSATYNLE-EILPLVGLSSLFDVEADLSG-IMGQLNKTVSRVSHKAVVDMNEKGTEAAAASGLLSQPPSLNMTSAPHAHFNRPFLLLLWEVTTQSLLFLGKVVNPAAG----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P35577-1", "uniprot_id": "THBG_RAT", "id": "P35577-1", "name": "Thyroxine-binding globulin", "aln": "---------------------------MS-MFFYLFLLVLGLQATIHCAPH-----NSSEGKVTTCHLPQQNATLY-KMPSINADFAFRLYRKLSVE--NPDLNIFFSPVSISAALAMLSFGSGSSTQTQILEVLGFNLTD-TPVKELQQGFQHLICSLNFPNNELELQMGNAVFIGQQLKPLAKFLDDVKTLYETEVFSTDFSNVSAAQHEINSYVEKQTKGKIVGLIQ--DLKLNIIMILVNYIHFKAQWANPFRVSKTEESSNFSVDKSTTVQVPMMHQLEQ-YYHYVDVELNCTVLQMDYSA----------------NALALFVLPK----EGHMEWVEAAMSSKTLKKWNHLLQK---GWV-ELFVPKFSISATYDLG-STLQKMGMRDAFAESADFPG-ITKDNGLKLSYAFHKAVLHIGEEGTKEGASPEAGSLDQPEVAPLHAVIRLDRTFLLMILEKRTRSVLFLGKVVDPTKE----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P61939-1", "uniprot_id": "THBG_MOUSE", "id": "P61939-1", "name": "Thyroxine-binding globulin", "aln": "---------------------------MS-VFFYLFVLVFGLQATIHCAPH-----NSSEGKVTTCHLPQQNATLY-KMPSINADFAFSLYRRLSVE--NPDLNIFFSPVSISVALAMLSFGSGSSTQTQILEVLGFNLTD-TPVTELQQGFQHLICSLNFPKNELELQMGNAVFIGQQLKPLAKFLDDVKTLYETEVFSTDFSNVSAAQHKINSYVEKQTKGKIVGLIQ--GLKLNIIMILVNYIHFRAQWANPFRVSKTEESSNFSVDKSTTVQVPMMHQLEQ-YYHYVDMELNCTVLQMDYSE----------------NALALFVLPK----EGHMEWVEAAMSSKTLKKWNYLLQK---GWV-ELFVPKFSISATYDLG-STLQKMGMRDAFAESADFPG-ITEDSGLKLSYAFHKAVLHIGEEGTKEGASPEVGSLDQQEVPPLHPVIRLDRAFLLMILEKRTRSVLFLGKLVNPTKQ----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZAT4-1", "uniprot_id": "D3ZAT4_RAT", "id": "D3ZAT4-1", "name": "", "aln": "---------------------------MG-SSFYRVLLVVGFCAPMSCMLS-----FNSNHRECPHPLSMKRNPAS-QVTPSNTKFAFLLYQRLAQK--SPGQNILFSPVSISTSLAMLSLGACSATKTQILRSLGFNITH-IAEHTIHLGFEQLVHSLNECHKDLELRMGSVLFIRKELQLQVKFLDRVKKLYGTKVFSEDFSNAVTAQAQINSYVERETKGKVVDVIQ--DLDSQTAMVLVNHIFFKANWTQPFSAANTNKSFPFLLSKGTTVHVPMMHQTES-FAFGVDRELGCSILQMDYRG----------------DAVAFFVLPG----KGKMRQLERSLSPRRLRRWSRSLQK---RWI-KVFIPKFSISASYNLE-TILPEMGIRDAFNSNADFSG-ITKTHFLQVSKAAHKAVLDVSEEGTEAAAATTTKLIVRSRDTPS-STIAFNEPFLILLLDKNTESILFLGKVENPRKM----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D7D2-1", "uniprot_id": "SPA9_MOUSE", "id": "Q9D7D2-1", "name": "Serpin A9", "aln": "---------------------------MGSSSFYRVLLLVGFCAPIFCMLS-----SNPYNQESSHLPSMKKNPAS-QVSPSNTRFSFLLYQRLAQE--NPGQNILFSPVSISTSLAMLSLGARSATKTQILRTLGFNFTW-VSEPTIHMGFEYLVRSLNKCHQGRELRMGSVLFIRKELQLQATFLDRVKKLYGAKVFSEDFSNAATAQAQINSYVEKETKGKVVDVIQ--DLDSQTAMVLVNHIFFKANWTQPFSTANTNKSFPFLLSKGTTVHVPMMHQTES-FAFGVDKELGCSILQMDYRG----------------DAVAFFVLPG----KGKMRQLEKSLSARRLRKWSRSLQK---RWI-KVFIPKFSISASYNLE-TILPKMGIRDAFNSNADFSG-ITKTHFLQVSKAAHKAVLDVSEEGTEAAAATTTKLIVRSRDTPS-SIIAFKEPFLILLLDKNTESVLFLGKVENPRKM----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86WD7-1", "uniprot_id": "SPA9_HUMAN", "id": "Q86WD7-1", "name": "Serpin A9", "aln": "---------------------------MA-SYLYGVLFAVGLCAPIYCVSP-----ANAPS-AYPRPSSTKSTPAS-QVYSLNTDFAFRLYRRLVLE--TPSQNIFFSPVSVSTSLAMLSLGAHSVTKTQILQGLGFNLTH-TPESAIHQGFQHLVHSLTVPSKDLTLKMGSALFVKKELQLQANFLGNVKRLYEAEVFSTDFSNPSIAQARINSHVKKKTQGKVVDIIQ--GLDLLTAMVLVNHIFFKAKWEKPFHPEYTRKNFPFLVGEQVTVHVPMMHQKEQ-FAFGVDTELNCFVLQMDYKG----------------DAVAFFVLPS----KGKMRQLEQALSARTLRKWSHSLQK---RWI-EVFIPRFSISASYNLE-TILPKMGIQNVFDKNADFSG-IAKRDSLQVSKATHKAVLDVSEEGTEATAATTTKFIVRSKDGPSYFTVSFNRTFLMMITNKATDGILFLGKVENPTKS----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LNG6-1", "uniprot_id": "A0ABK0LNG6_RAT", "id": "A0ABK0LNG6-1", "name": "", "aln": "MYVPPWFPAPARDFSKPGGLLPIKTLSHHNTEMAATMRFFPILCLVLFFSHG---VASRQRSHSKEKKKSKESSVGAVGTSRSRDFAFRLYRALASE--APGQNVFFSPMSVSMSLGMLSLGSGLKTKAQILEGLGLSLQQ-GQEDMLHKGFQQLLQQFSQPSDGLQLSLGSALFTDPAVHIRDHFLSAMKTLYMSDMFSTNFGNPESAKKQINDYVAKKTNGKIVDLIK--DLDSTHVMVVVNYIFFKAKWQTAFSSTNTHK-MDYHVTPKKTIQVPMMNREDI-YSYILDQNISCTVVGIPYQG----------------NTFALFILPS----EGKMKRVEDGLDERTLRNWLKMFTK---RQL-DLYLPKFSIEGTYKLE-KILPKLGIQDIFTTHADLSG-LTDHTNIKLSEMVHKSMVEVDESGTTAAASTGILFTLRS-ARPSSLKVEFTRPFLVVIMDGT--NLYFIGKVIQP-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P70458-1", "uniprot_id": "IPSP_MOUSE", "id": "P70458-1", "name": "Plasma serine protease inhibitor", "aln": "------------------------------------MRFFPILCLVLFISHG---VASRRHSHSK-KKKAKESSVGAVGPPSSKDFAFRLYRALVSE--SPGQNVFFSPLSVSMSLGMLSLGAGLKTKTQILDGLGLSLQQ-GQEDKLHKGFQQLLQRFRQPSDGLQLSLGSALFKDPAVHIRDDFLSAMKTLYMSDTFSTNFGNPEIAKKQINNYVAKQTKGKIVDFIK--DLDSTHVMIVVNYIFFKAKWQTAFSETNTHK-MDFHVTPKRTTQVPMMNREDG-YSYYLDQNISCTVVGIPYQG----------------NAIALFILPS----EGKMKQVEDGLDERTLRNWLKMFTK---RRL-DLYLPKFSIEATYKLE-NVLPKLGIQDVFTTHADLSG-ITDHTNIKLSEMVHKSMMEVEESGTTAAAITGAIFTFRS-ARPSSLKIEFTRPFLLTLMEDS--HILFVGKVTRP-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F8W5D3-1", "uniprot_id": "F8W5D3_DANRE", "id": "F8W5D3-1", "name": "Thyroxine-binding globulin", "aln": "------------------------------MERNGVLLWIFGFAIVVCGNQ-------------ETLQQPPISAKLPSLINMNNDFAFHLYKRVIELPDYQSKNIFFSPFSVSMALSELSLGAGGDTKQQLLSGIGYNSTI-FSTEEMHQLFHSLLEDISN-RTGVDIDVGTALYASDRFKPHSKFLEDMKEFYHSDGFTVDFR-VKETVDQINNYAKKKTQGKINQAVD--NLEDDTLMFLLTYIYFKGKWDKPFKPEKTRE-STFHIDDKTTVTVQMMHQYER-LKVFYDAELSTKVLCLDYKD----------------SFSMFLAVPDDKMEQKNIKDLEMTVSRQHVEKWKRSAFK----KTVDIYVPKLSLKTSYSLK-DILKGMGMADIFSDKANFTG-VSEEK-IFVSKVLHKATLDIDEQGTTAAAVTGVSMRVRLHNPLS--ILKFNRPFMIFITDQTNDNILFFGKVVNPNEKL---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q00896-1", "uniprot_id": "A1AT3_MOUSE", "id": "Q00896-1", "name": "Alpha-1-antitrypsin 1-3", "aln": "---------------------------MTPSISWGLLLLAGLCCLVPSFLA--------EDVQETDTSQKDQSPASHEIATNLGDFAISLYRELVHQ--SNTSNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQ-TSEADIHKSFQHLLQTLNRPDSELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNFAESEEAKKVINDFVEKGTQGKIVEAVK--KLDQDTVFALANYILFKGKWKKPFDPENTEE-AEFHVDESTTVKVPMMTLSGMLDVHHCS-TLSSWVLLMDYAG----------------NATAVFLLPD----DGKMQHLEQTLSKELISKFLLNRRR----RLAQIHFPRLSISGEYNLK-TLMSPLGITRIFNNGADLSGITEENAPLKLSQAVHKAVLTIDETGTEAAAVTVLLAVPYSMPP----ILRFDHPFLFIIFEEHTQSPLFVGKVVDPTH-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P07758-1", "uniprot_id": "A1AT1_MOUSE", "id": "P07758-1", "name": "Alpha-1-antitrypsin 1-1", "aln": "---------------------------MTPSISWGLLLLAGLCCLVPSFLA--------EDVQETDTSQKDQSPASHEIATNLGDFAISLYRELVHQ--SNTSNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQ-TSEADIHKSFQHLLQTLNRPDSELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNFAESEEAKKVINDFVEKGTQGKIAEAVK--KLDQDTVFALANYILFKGKWKKPFDPENTEE-AEFHVDESTTVKVPMMTLSGMLHVHHCS-TLSSWVLLMDYAG----------------NATAVFLLPD----DGKMQHLEQTLSKELISKFLLNRRR----RLAQIHFPRLSISGEYNLK-TLMSPLGITRIFNNGADLSGITEENAPLKLSQAVHKAVLTIDETGTEAAAVTVLQMVPMSMPP----ILRFDHPFLFIIFEEHTQSPIFLGKVVDPTHK----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22599-1", "uniprot_id": "A1AT2_MOUSE", "id": "P22599-1", "name": "Alpha-1-antitrypsin 1-2", "aln": "---------------------------MTPSISWGLLLLAGLCCMVPSFLA--------EDVQETDTSQKDQSPASHEIATNLGDFAISLYRELVHQ--SNTSNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQ-TSEADIHKSFQHLLQTLNRPDSELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNFAESEEAKKVINDFVEKGTQGKIVEAVK--ELDQDTVFALANYILFKGKWKKPFDPENTEE-AEFHVDKSTTVKVPMMMLSGMLDVHHCS-ILSSWVLLMDYAG----------------NASAVFLLPE----DGKMQHLEQTLNKELISKILLNRRR----RLVQIHIPRLSISGDYNLK-TLMSPLGITRIFNNGADLSGITEENAPLKLSKAVHKAVLTIDETGTEAAAATVFEAVPMSMPP----ILRFDHPFLFIIFEEHTQSPIFVGKVVDPTHK----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00897-1", "uniprot_id": "A1AT4_MOUSE", "id": "Q00897-1", "name": "Alpha-1-antitrypsin 1-4", "aln": "---------------------------MTPSISWSLLLLAGLCCLVPSFLA--------EDVQETDTSQKDQSPASHEIATNLGDFALRLYRELVHQ--SNTSNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQ-TSEADIHKSFQHLLQTLNRPDSELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNFAESEEAKKVINDFVEKGTQGKIVEAVK--KLDQDTVFALANYILFKGKWKQPFDPENTEE-AEFHVDESTTVKVPMMTLSGMLDVHHCS-MLSSWVLLMDYAG----------------NTTAVFLLPD----DGKMQHLEQTLNKELISQFLLNRRR----SDAQIHIPRLSISGNYNLK-TLMSPLGITRIFNNGADLSGITEENAPLKLSKAVHKAVLTIDETGTEAAAATVLQVATYSMPP----IVRFDHPFLFIIFEEHTQSPIFVGKVVDPTHK----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00898-1", "uniprot_id": "A1AT5_MOUSE", "id": "Q00898-1", "name": "Alpha-1-antitrypsin 1-5", "aln": "---------------------------MTPSISWCLLLLAGLCCLVPSFLA--------EDVQETDTSQKDQSPASHEIATNLGDFAISLYRELVHQ--SNTSNIFFSPVSIATAFAMLSLGSKGDTHTQILEGLQFNLTQ-TSEADIHNSFQHLLQTLNRPDSELQLSTGNGLFVNNDLKLVEKFLEEAKNHYQAEVFSVNFAESEEAKKVINDFVEKGTQGKIVEAVK--KLEQDTVFVLANYILFKGKWKKPFDPENTKQ-AEFHVDESTTVKVPMMTLSGMLDVHHCS-TLSSWVLLMDYAG----------------NATAVFLLPD----DGKMQHLEQTLNKELISKFLLNRRR----RLAQIHIPRLSISGNYNLE-TLMSPLGITRIFNSGADLSGITEENAPLKLSQAVHKAVLTIDETGTEAAAATVLQGGFLSMPP----ILHFNRPFLFIIFEEHSQSPLFVGKVVDPTHK----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A4R7-1", "uniprot_id": "D4A4R7_RAT", "id": "D4A4R7-1", "name": "", "aln": "--------------------------MTAPFFSRGLLLLVGLCCLLPITKT--------KYEDLYEDPNIDP-FQCRKVALTISNISITLFKEMAQL--SVNGNILFSPIRVIAAISMLSLGAKGNESKRILEILRLNKTG-LPEAEIHKCFRYLLRAIHQPEQLSPLKSGSGVFIHQDLTPVDKFVEGVKNLYHSDIVSINFTDCRRAKTQINNYMMTKSNKEIKNIVK--NLENDTYMAVVNYIIWNAKINSDFGCRSVKQ-KDYHLEQGMTIKVPMIHIVDLNHLFRVE-DLSSTVLVFTLLAS---------------NFTTYFIIPD----IGQMQKVEQRLTYPHFRRMRRQSNL----RMVNLETPELSLSETHDVE-SMMNLLGITYVFNNDANSSAV-MNDTLQKSFKMVSKVKLTIDDKGSKPGRSTCFKNDGSVDVG----YVQFNRPFLIFIKDPTNDVPLFLGRVVNPKH-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCQ7-1", "uniprot_id": "A1AT6_MOUSE", "id": "Q9DCQ7-1", "name": "Alpha-1-antitrypsin 1-6", "aln": "--------------------------MTTPFSSHGLLLLVGLCCLLLITKT--------KHEKLYEDPSIDP-FQCRKVALTICNVSITLFKKMAQL--SGNGNILFSPIRVIAAISMLSLGSNGNLSKHILETLRFNKTG-LPEAEIHKCFWYLLHSIHQTEETSSLQTGSSVFIHQDLTSVDKFVKGVKELYHSDMISINFTDSSQAKTQINNYVMEISQKAIVNIVK--NLESDTFLAVVNYIIWNAKLDSNFGCRSVKV-KDYHLGYGMTIKVPMIHNMAMHYLFRVG-DLSSTVLMLTLLTG---------------NFATYFIIPD----PGKMQKVEQSLTYPHFRRMRRQLLT----RLVDLEIPELSLSETHDLE-SMMSLLGITYVFNSGTNSSD--MNDTLQKSFKVVSKAVLTIDEKGSKPSTNSCFKKLGSTDMG----RMQLNRPFLIFIQDHTNDVPLFLGRVVNPQN-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8R4Z1-1", "uniprot_id": "SPA12_RAT", "id": "Q8R4Z1-1", "name": "Serpin A12", "aln": "---------------------------MNLVLGLGLFLAGLLTVKGLLQDR----DAPDTYESPVRVQEWRGKKDARELTRHNMEFGFKLLQRLASN--SRQGNIFLSPLSISTAFSMLSLGAQNSTLEEIREG--FNFKE-MSDRDMHMGFHYLLQKLNRETQDVKMSIGNALFMDQRLRPQQRFLKLAKNLYDADMILTNFQDLENTQKNINKYISRKTHNRIENMVK--NIDPGTVMLLTNYIYFQGRWQYEFDPKQTKE-EDFFIEEGKTVKVPMMFQR-GMYDMAYDSQLSCTILEMPYRG----------------NITATFVLPD----SGKLRLLEQGLQADIFAKWKSLLSK----RVVDVWVPRLHISATYNMK-KVLSRLGISKIFEEHGDLTR-ISSHRSLKVGEAVHKAELRMNEKGTEGAAGSGAQTLPMETPR----RMKLNAPFLMMIYENLMPSMIFLARIYNP-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TMF5-1", "uniprot_id": "SPA12_MOUSE", "id": "Q7TMF5-1", "name": "Serpin A12", "aln": "---------------------------MTRMLDLGLFLAGLLTVKGLLQDR----DAPDMYDSPVRVQEWRGKKDARQLARHNMEFGFKLLQRLASN--SPQGNIFLSPLSISTAFSMLSLGAQNSTLEEIREG--FNFKE-MSNWDVHAAFHYLLHKLNQETEDTKMNLGNALFMDQKLRPQQRFLNLAKNVYDADMVLTNFQDLENTQKDINRYISQKTHSRIKNMVK--SIDPGTVMILTNYIYFRGRWQYEFDPKQTKE-EEFFIEKGKTVKVPMMFQR-GLYDMAYDSQLSCTILEIPYRG----------------NITATFVLPD----NGKLKLLEQGLQADIFAKWKSLLSK----RVVDVWVPKLRISSTYNMK-KVLSRLGISKIFEENGDLTR-ISSHRSLKVGEAVHKAELKMDEKGMEGAAGSGAQTLPMETPR----HMKLDRPFLMMIYENFMPSMVFLARIYDPSG-----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IW75-1", "uniprot_id": "SPA12_HUMAN", "id": "Q8IW75-1", "name": "Serpin A12", "aln": "---------------------------MNPTLGLAIFLAVLLTVKGLLKPS----FSPRNYKALSEVQGWKQRMAAKELARQNMDLGFKLLKKLAFY--NPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQG--FNFRK-MPEKDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETILTNFQNLEMAQKQINDFISQKTHGKINNLIE--NIDPGTVMLLANYIFFRARWKHEFDPNVTKE-EDFFLEKNSSVKVPMMFRS-GIYQVGYDDKLSCTILEIPYQK----------------NITAIFILPD----EGKLKHLEKGLQVDTFSRWKTLLSR----RVVDVSVPRLHMTGTFDLK-KTLSYIGVSKIFEEHGDLTK-IAPHRSLKVGEAVHKAELKMDERGTEGAAGTGAQTLPMETPL----VVKIDKPYLLLIYSEKIPSVLFLGKIVNPIGK----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9VFC1-1", "uniprot_id": "Q9VFC1_DROME", "id": "Q9VFC1-1", "name": "", "aln": "------------------------------MHTFSLVLLALLPVVTIAALD---------------KPELSFLNEFSQIFKGERDFSLALMKQIREI--YPSGNLFFSPFSTYNALLLAYFSSSEQTERELAQALNLGWALNKQQVLVSYTLAQRQDEFRWRQSPMELSSANRIFVDRTINVSNKFN---TLLYGATKELDFKNDPETGLKEINDWIADKTHNQIRDMLSSEEITPHTMLVLANAAYMKGQWLSQFKVEETAL-KPFFINEREQEMVYMMHKT-GAFKMTIDEGLQSQIIKLPYRTIYKSKETHISTPESKSDISMIIILPNS--NKISLNRVISRLNADSVKKWFERALP----QKIELSLPKFQFEQRLELT-PILSLMGVNTMFTRNATFGDLTADPISLVIDDAQHLAKIKVDEVGSTAAAAT-ILLVSRSSRQPDPTKFNCNHPFVFLIYDEKVDTILFAGVYSDPRQMQH--------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : : * :**. :. .: . : : : : . : : * :* : : . : : : . .. * . : : *: :: : : :* : : : . : *.. . : : :.. : : : : :: . . * ", "identical_positions": 10, "similar_positions": 59, "identity": "1.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110407-9", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5RKG6-1", "uniprot_id": "TRI35_RAT", "id": "Q5RKG6-1", "name": "E3 ubiquitin-protein ligase TRIM35", "aln": "-MEPGPSVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRRCVSGCWEVQTTP-SCPVCKERAVPGELRTNHTLNNLVETLLREEAEGARWTGRRSPRPCRAHRAPLTLFCVEDKELLCCACQADARHQEHRVQPIKDTAQDFRAKCKNMEHVLREKAKSFWALR-RTYEAIAKHNEVQTTWLEGRIRDEFDKLRDFLRVEEQATVDAMKEESRKKHLLAEEKMKQLAEQTEALAREIERLQMEMKEDDMTFLMKHKSRKRRLFCTVEPAPLQPGLLMDACKYLESLQYRVWKKMLGSVESVPFSLDPNTAAGWLKVADDLTSVINHGYRVQVE-NPERFSSAPCLLGSQVFSKGSHSWEVDVGGLPSWRVGVVRVQAHAQAQAQADVGGEGHSHSCYHDTRSGFWYLCRTQGVDGDHCMTSDTATAPLVQAMPRRLRVELECEEGELSFYDSERHCHLYTFH-AHFG-EVRPYFYLGASRGDGPPEPLRICHLRVSIKEELDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C006-1", "uniprot_id": "TRI35_MOUSE", "id": "Q8C006-1", "name": "E3 ubiquitin-protein ligase TRIM35", "aln": "-MEPGPSVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRRCVSGCWEVQTTP-SCPVCKERAVPGELRTNHTLNNLVETLLREEAEGARWTGRRSPRPCRAHRAPLTLFCLEDKELLCCACQADARHQEHRVQPIKDTAQDFRAKCKNMEHVLREKAKAFWALR-RTYEAIAKHNEVQTTWLEGRIRDEFDKLRDFLRVEEQATLDAMKEESRKKHLQAEEKMKQLAEQTEALAREIERLQMEMKEDDMTFLMKHKSRKRRLFCTVEPAPLQPGLLMDACKYLESLQYRVWKKMLGSVESVPFSLDPNTAAGWLKVADDLTSVINHGYRVQVE-NPERFSSAPCLLGSQVFSKGSHSWEVDVGGLPTWRVGVVRVQAHAQAQAQADVGGEGHSHSCYHDTRSGFWYLCRTQGVDGDHCMTSDTATAPLVQAMPRRLRVELECEEGELSFYDSERHCHLYTFH-AHFG-EVRPYFYLGASRGDGPPEPLRICHLRVSIKEELDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPQ4-1", "uniprot_id": "TRI35_HUMAN", "id": "Q9UPQ4-1", "name": "E3 ubiquitin-protein ligase TRIM35", "aln": "-MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSP-TCPVCKDRASPADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMR-RSYEAIAKHNQVEAAWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQVE-NPERFSSAPCLLGSRVFSQGSHAWEVALGGLQSWRVGVVRVRQ--------DSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFH-ARFG-EVRPYFYLGGARGAGPPEPLRICPLHISVKEELDG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q7P5-1", "uniprot_id": "A0A8M1Q7P5_DANRE", "id": "A0A8M1Q7P5-1", "name": "", "aln": "-----------MASSAEYDYSCPVCHDIFKTPVILSCTHSFCKECLQQFWRSKNTQ-ECPVCRRRSSKKDLPVNLALKNLCESFLKERNE---RRSSGSEEICSLHSEKLKLFCLEDKQPVCLVCRDSEKHLGHTFRPLSEMAAENMEELNTALKSLQEKLKHNENIK-EEFEKSVQHIKAQAEHTERQIKQQFKKLHQFLRDEEEATITALREEEEQKKQMMKEKLEEMNTHISALSHTIKDTEEMLKANDVCFLKEFPVSMERVQISQPDPQMPSGALIHVSRYLGNLPFRVWKKMQDIVQYTPVILDPNTAYPEFVVSDDLTSVTFSENKQPVPDNPERFDYYPFVLGSEGFNSGKHCWDVEVNRSFEWRVGVTTASN----------------------QRKGQVFLN--SDVWSVYYYAHGLLATGFCGSDLDRVRVDLDYDRGTVSFSDPVNNEHLHTYT-TTFTDTVFPFIYCWRS-------SLRILPFSSQ-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D4A221-1", "uniprot_id": "D4A221_RAT", "id": "D4A221-1", "name": "", "aln": "MSVHEKISTADLMENLREELTCFICLDYFSSPVTTECGHSFCLTCLLKSWEEHNTPLSCPECWRTLGAPHFQANERLGRLAN--IGRQLRCQVLQSEDEQSNSGRTPGPSRVFSDDEQSVINFSPPN---HGMNRAYFSSEAEEQHKEKLQDIVNILRKRKKEAQAILNHEKERVMLCKQEETKTCKQVVVSEYMKMHQFLKEEEQLQLQLLEKEEKENVKKLRENEIHLTQQVRRINKMIGRIESICQNLTLESFEEVRGAMDRYESLLFQCPETTITELSLCRITG------MREMLRKFS-TDITLDPATANAYLLLSDDLKSVRYGGTKQQLPDNPERFDQSATVLGAQIFTCGRHYWEVEVGKKTEWEVGICKDSVN--------------RKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVHKVGVFLDYDSGHIAFYNVTDESLIYSFPPSSFHEALRPIFSPCLPNEGTNTDPLIICHI----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N9V2-1", "uniprot_id": "TRIML_HUMAN", "id": "Q8N9V2-1", "name": "Probable E3 ubiquitin-protein ligase TRIML1", "aln": "------MSTADLMENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEEHNTPLSCPECWRTLEGPHFQSNERLGRLAS--IARQLRSQVLQSEDEQGSYGRMPTTAKALSDDEQGGSAFVAQS---HGANRVHLSSEAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLC-QEETKTCKQVVVSEYMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMIAQIESSSQSSAFESLEEVRGALERSEPLLLQCPEATTTELSLCRITG------MKEMLRKFS-TEITLDPATANAYLVLSEDLKSVKYGGSRQQLPDNPERFDQSATVLGTQIFTSGRHYWEVEVGNKTEWEVGICKDSVS--------------RKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVCKVGVFLDYESGHIAFYNGTDESLIYSFPQASFQEALRPIFSPCLPNEGTNTDPLTICSLNSHV------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : * :* * * .* * *.** *: *. : : ** * .: * * .* . : .. . . :. ::: * : .: . : . : *: : * : . * : :: : : .:: *:::**: **: : : :* .:: :: .: . : : * : : . : : * . : .: ::* .. . . :** ** : :::**.** : : *****. . :**:. *. * * *:* :. *.**: . : . . . . :: * *: : * ::* : . :::: : * : * : . .* * : ", "identical_positions": 61, "similar_positions": 119, "identity": "12.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-13", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P19440-1", "uniprot_id": "GGT1_HUMAN", "id": "P19440-1", "name": "Glutathione hydrolase 1 proenzyme", "aln": "MKKKLVVLGLLAVVLVLVIVGLCLWLPS----ASKEPDNHVYTRAAVAADAKQCSKIGRDALRDGGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMF-NSSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALENKRTVIEQQPVLCEVFCR-DRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKDIQAAGGIVTAEDLNNYRAELIEHPLNISLGDVVLYMPSAPLSGPVLALILNILKGYNFSRESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISDDTTHPISYYKPEFYTPDDGGTAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNNEMDDFSSPSITNEFGVPPSPANFIQPGKQPLSSMCPTIMVGQDGQVRMVVGAAGGTQITTATALAIIYNLWFGYDVKRAVEEPRLHNQLLPNVTTVERNIDQAVTAALETRHHHTQIASTFIAVVQAIVRTAGGWAAASDSRKGGEPAGY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60928-1", "uniprot_id": "GGT1_MOUSE", "id": "Q60928-1", "name": "Glutathione hydrolase 1 proenzyme", "aln": "MKNRFLVLGLVAVVLVFVIIGLCIWLPY----TSGKPD-HVYSRAAVATDAKRCSEIGRDILQEGGSVVDAAIASLLCMGLMNAHSMGIGGGLFFTIYNSTTGKVEVINAREVAPRLANTTMF-NNSKDSEEGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARHGFPVGKGLAIALDKKRDVIEKTPALCEVFCR-QGKVLQEGETVTMPKLADTLQILAQEGAKAFYNGSLTAQIVKDIQEAGGIMTVEDLNNYRAELIEHPMSIGLGDATLYVPSAPLSGPVLILILNILKGYNFSPKSVATPEQKALTYHRIVEAFRFAYAKRTMLGDPKFVDVSQVIRNMSSEFYATQLRARITDETTHPAAYYEPEFYLQDDGGTAHLSAVSEDGSAVAATSTINLYFGSKVLSRVSGILFNDEMDDFSSPNFINQFRVAPSPANFIKPGKQPLSSMCPSIILDKDGQVRMVVGASGGTQITTSVALAIINSLWFGYDVKRAVEEPRLHNQLLPNTTTVEKDIDQVVTAGLKIRHHHTEVTPTFIAVVQAVVRASGGWAAASDSRKGGEPAGY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B6V1-1", "uniprot_id": "A0ACD6B6V1_DANRE", "id": "A0ACD6B6V1-1", "name": "Glutathione hydrolase", "aln": "MVQKSTVAGLVLLLLAAVGTFLAVFFSVQGKKASSDPE-SGFFKAAVATDAGTCSEIGRDVLKKGGSAVDSAIAALLCAGLMNAHSMGIGGGLFFTIYDAKTGKAETINARETAPANATRDMFGNSTELSQKGGLSIAVPGEIRGYEMAHRRHGRLPWRELFLPSIKLARDGFPVGRALASAIRSNRNNILEDKMLCSVFCNSTGNILQENDTITFTKLADTYEAIAEQGPEAFYSGALAESLVRDIQDADGIITLADLRDYRALLDEYPPTASVGEFTMVTPDAPSSGPVLTLMLNILSGYSLSPDSVSSTEKKILTYHRVVEAFRFAYAKRSVLGDPQFLNISDFIQNITSKGYADMIRLKITDNSTQQESFYEPEFYLPENYGTSHVSVVAEDGSAVAATSTINTYFGSKLMSKSTGILLNNEMDDFSSPLITNNFGVPPSPNNFIVPNKRPMSSMCPAILLDKNNQVKMVVGASGGTKITTAVAQVVLNTLFFQYDLKKAIAEARVHNQLSPNTTQVEQSFDKAVLEGLAEKNHFTEVFTSMGAVVQAVARYSEGLSAESDPRKGGYAAGY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :: * **: ::*. * *.:::. :* .*: : :****:** **:**** *:.***.**:***:*** ***************:***::.* *.*.*****.** * ** *.:: *::****:**********:**:******* .** ***:***.*****:.** *: .:* * : **.***. ::*:*.: :*:.:**** : :* :*.:***.*:*: .:*:*** *.**:* **.:*** * *:* . .:*: .: *.** ***** *:****.**.:* .** :.*:* *****:***********::****:*:::::.::*::*: :* :* :*:*::*: ::*:**** :: **:*:*.*:******:****** *****: * :***:*:******** : *:* *.*** *** *.*:*:*****:*::.::.**:*****:***:***:.* .:: .*:* **:*:*: *.*:**** **.* **:.:*:.* .* ::*.*:: .:: *****:.* : * :* **.**** .***", "identical_positions": 302, "similar_positions": 174, "identity": "52.52%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-14", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VME7-1", "uniprot_id": "Q9VME7_DROME", "id": "Q9VME7-1", "name": "Fibrinogen C-terminal domain-containing protein", "aln": "--------------------------------------------MRSVWIYVAFLGLSFYSTEAMDSESFQNDTAIRNKPELKSLYKLVLALLEENQSNASTENIQKSSSDLNTTGLSGRYP----------------------------------------------------------------------------------------SQCPTYPPAHGIYTVQVLGLKPFQVSCD-AEIAG-----TGWTVMARRTSNKLNFFRSWAEYKNGFGQLDGDFFIGLDKLHAITKSQPHELYIHLEDFEGQTRYAHYDEIFIE-----SENKFYAMTKLGEFTGDAGDSMIHNRNQNFSTFDRDNDG-WHKNCAEEYVGAWWHLNCT----YSNLFGIYVKGDEGQ-YFQWKGIVWHSWRT-ESYSYKVMQMMVRPKCHCSG-----------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4K7T3-1", "uniprot_id": "A0A0B4K7T3_DROME", "id": "A0A0B4K7T3-1", "name": "Fibrinogen C-terminal domain-containing protein", "aln": "--------------------------------------------MKPICFALCVFSLG--------------------------LFYLASAEIGENVKIQTYKKYSSSCKELN-------------------------------------------------------------------------------------------------------PKKSGVQKIQV-GSDVIEVYCD-VTIAG-----KGWLVVQRRVSVEENFYRNWTSYQTGFGDLKGNFFIGLNNLNKISSLQPQELYIELVDFAGEKRYAHYSVFHVG-----NVYSNYPITQLGAYSGTAGDSLSYHLYQPFSTFDRDNDN-ATINCAARYMGAWWYRECLSRIPCSNLNGAYLGGNHTDPALFGSGIVWGEWKG-FTYSYKTVNIMVRPK----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z7G6-1", "uniprot_id": "A1Z7G6_DROME", "id": "A1Z7G6-1", "name": "Fibrinogen C-terminal domain-containing protein", "aln": "----MEYYSIILILIMLPSAWCLQVPSKIKSTTKAPVKEIPPTNGTQIGNVTAVAPVPEKLAEVHIDQHKTIRISKGDLDDLLDVYMGKIAESAATIKDKENEINKLQTKDQTGDELLRKFENLTQVCSAQQSSFTTAIKEKDEQIKELEQKVKVYETRLKRKQHVLAELRKLNGSSALLIEHLKGKVVYFERKFREKKDDLLADWEAATTSCVPFGRSPGIHLIHLPGFLPFLVPCEGQTAAG-----PGWTCIQRRLDGSVNFYRNWDAYSKGFGKLNGEFFIGLEKLHRLTSSQPHELYISIRRFGGETSYAHYDDFLIG-----SEEEGYELKLLGHYQGNASDALRTHDKMKFSTYDRDNDAFTHMNCAEHHQGAWWYDFCS----RSNLNGRYFKGEVDN----PQSIYWEPWYS-FR-SLKSVQMLIRPKSQLELKDLPRPMRPPG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "G3V6A9-1", "uniprot_id": "G3V6A9_RAT", "id": "G3V6A9-1", "name": "Microfibril-associated glycoprotein 4", "aln": "MSLSLNLEVMGLGRLVALQLRTALPSAGIAGMLCLYPCLCAACAGGPQRPESASDLLGLELEVPGTCQTLSGLPLLLLLLSTPPPCAPQASGIRGDALEKSCLQQPLDCDDIYMQG----------------------------------------------------------------------------------------------------YQEDGVYLIYPYGPSVPVPVFCDMTTEG-----GKWTVFQKRFNGSVSFFRGWNDYKLGFGRADGEYWLGLQNLHLLTLKQKYELRVDLEDFENNTAYAKYVDFSISPNAVSAEEDGYTLYVAGFEDGGAGDSLSYHSGQKFSTFDRDQDL-FVQNCAALSSGAFWFRSCH----FANLNGFYLGGSHLS---YANGINWAQWKG-FYYSLKRTEMKIRRA----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D1H9-1", "uniprot_id": "MFAP4_MOUSE", "id": "Q9D1H9-1", "name": "Microfibril-associated glycoprotein 4", "aln": "------------------------------------------------------------------MKALPALPLMLMLLSMPPPCAPQASGIRGDALEKSCLQQPLDCDDIYAQG----------------------------------------------------------------------------------------------------YQEDGVYLIYPYGPSVPVPVFCDMTTEG-----GKWTVFQKRFNGSVSFFRGWSDYKLGFGRADGEYWLGLQNLHLLTLKQKYELRVDLEDFENNTAYAKYIDFSISPNAISAEEDGYTLYVAGFEDGGAGDSLSYHSGQKFSTFDRDQDL-FVQNCAALSSGAFWFRSCH----FANLNGFYLGGSHLS---YANGINWAQWKG-FYYSLKRTEMKIRRA----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55083-1", "uniprot_id": "MFAP4_HUMAN", "id": "P55083-1", "name": "Microfibril-associated glycoprotein 4", "aln": "------------------------------------------------------------------MKALLALPLLLLLS--TPPCAPQVSGIRGDALERFCLQQPLDCDDIYAQG----------------------------------------------------------------------------------------------------YQSDGVYLIYPSGPSVPVPVFCDMTTEG-----GKWTVFQKRFNGSVSFFRGWNDYKLGFGRADGEYWLGLQNMHLLTLKQKYELRVDLEDFENNTAYAKYADFSISPNAVSAEEDGYTLFVAGFEDGGAGDSLSYHSGQKFSTFDRDQDL-FVQNCAALSSGAFWFRSCH----FANLNGFYLGGSHLS---YANGINWAQWKG-FYYSLKRTEMKIRRA----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z1Z6-1", "uniprot_id": "A0A8M6Z1Z6_DANRE", "id": "A0A8M6Z1Z6-1", "name": "", "aln": "------------------------------------------------------------------------MAIVLFLAT-----------LLSAALASDCTSMPFDCSDIYKSG----------------------------------------------------------------------------------------------------ETLSGVYTIYPAG-ETPVWVYCQMLSDGKDEENGGWTVIQRRMDGSVNFYRPWRDYKRGFGNVEGEYWLGLENLYQLTRHKKFMLRVDLEDFEGRRGFAQYSSFSVG-----CECEGYKLQVSGFTDGGAGDSLSPHNGMKFSTFDKDQDT-YEKNCAKEFLGGFWYSSCH----NTNPNAVYLWEEDVTH--HAIGVSWYSWKGTHAVSMKTISMKIKQVP---------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: *: : * * * . :* . . .*:* * *. *** .*::::**::: :: : * : : * .. :*:* : : . * : * * *.*:: : ***:*:*:* *** *.:*. * :* . *. . .: * * * * .: :: ", "identical_positions": 42, "similar_positions": 53, "identity": "9.27%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-15", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10499-1", "uniprot_id": "KCNA1_RAT", "id": "P10499-1", "name": "Potassium voltage-gated channel subfamily A member 1", "aln": "MTVMS-----GENADEASAAPGHPQDG----------------------------------SYPRQADHDD---------------------HECCERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTIHRIDNTTVIYTSNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAE-QEGNQ-----------KGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQ--AQLLHVSS-PNLAS-------DSDLSRRSS------------------------------------STISKSEYMEIEEDMNNSIAHYRQANIR-------------------------------TGNCTATDQNCVNKSK-------------LLTDV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P16388-1", "uniprot_id": "KCNA1_MOUSE", "id": "P16388-1", "name": "Potassium voltage-gated channel subfamily A member 1", "aln": "MTVMS-----GENADEASTAPGHPQDG----------------------------------SYPRQADHDD---------------------HECCERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTIHRIDNTTVIYTSNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAE-QEGNQ-----------KGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQ--AQLLHVSS-PNLAS-------DSDLSRRSS------------------------------------STISKSEYMEIEEDMNNSIAHYRQANIR-------------------------------TGNCTTADQNCVNKSK-------------LLTDV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q09470-1", "uniprot_id": "KCNA1_HUMAN", "id": "Q09470-1", "name": "Potassium voltage-gated channel subfamily A member 1", "aln": "MTVMS-----GENVDEASAAPGHPQDG----------------------------------SYPRQADHDD---------------------HECCERVVINISGLRFETQLKTLAQFPNTLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPVNVPLDMFSEEIKFYELGEEAMEKFREDEGFIKEEERPLPEKEYQRQVWLLFEYPESSGPARVIAIVSVMVILISIVIFCLETLPELKDDKDFTGTVHRIDNTTVIYNSNIFTDPFFIVETLCIIWFSFELVVRFFACPSKTDFFKNIMNFIDIVAIIPYFITLGTEIAE-QEGNQ-----------KGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQ--AQLLHVSS-PNLAS-------DSDLSRRSS------------------------------------STMSKSEYMEIEEDMNNSIAHYRQVNIR-------------------------------TANCTTANQNCVNKSK-------------LLTDV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FFE9-1", "uniprot_id": "E7FFE9_DANRE", "id": "E7FFE9-1", "name": "", "aln": "MTVVA-----GDNMDETSAVPGHPQD-----------------------------------TYP--PDHDD---------------------HECCERVVINIAGLRFETQLKTLAQFPETLLGNPKKRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRLRRPANVPLDMFSEEIKFYELGVEAMEKFREDEGFIREEERPLPEKEFQRQIWLLFEHPESSGPARGIAIVSVMVILISIVIFCLETLPELKEDP--EGRIKIIGNTTYYYKPSILADPFFIIETLCIIWFSFELIVRFFACPSKAAFFKNMMNTIDIVAIIPYFITLGTELAEEQDGKEG----------KGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAEAEEKESYFSSIPDAFWWAVVSMTTVGYGDMVPVTIGGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETEGEEQ--AQLLNVSN-PNIAS-------DSNSSRRSS------------------------------------STVSKSEYMEIDGDINNSIDNFREANLR-------------------------------TGNCTIPNQNCVNKSK-------------LLTDV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08510-1", "uniprot_id": "KCNAS_DROME", "id": "P08510-1", "name": "Potassium voltage-gated channel protein Shaker", "aln": "MAAVAGLYGLGEDRQHRKKQQQQQQHQKEQLEQKEEQKKIAERKLQLREQQLQRNSLDGYGSLPKLSSQDEEGGAGHGFGGGPQHFEPIPHDHDFCERVVINVSGLRFETQLRTLNQFPDTLLGDPARRLRYFDPLRNEYFFDRSRPSFDAILYYYQSGGRLRRPVNVPLDVFSEEIKFYELGDQAINKFREDEGFIKEEERPLPDNEKQRKVWLLFEYPESSQAARVVAIISVFVILLSIVIFCLETLPEFKHYKVFNTTTN--GTKIEEDEVPDITDPFFLIETLCIIWFTFELTVRFLACPNKLNFCRDVMNVIDIIAIIPYFITLATVVAEEEDTLNLPKAPVSPQDKSSNQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGRTLKASMRELGLLIFFLFIGVVLFSSAVYFAEAGSENSFFKSIPDAFWWAVVTMTTVGYGDMTPVGVWGKIVGSLCAIAGVLTIALPVPVIVSNFNYFYHRETDQEEMQSQNFNHVTSCPYLPGTLGQHMKKSSLSESSSDMMDLDDGVESTPGLTETHPGRSAVAPFLGAQQQQQQPVASSLSMSIDKQLQHPLQQLTQTQLYQQQQQQQQQQQNGFKQQQQQTQQQLQQQQSHTINASAAAATSGSGSSGLTMRHNNALAVSIETDV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.:: *:: :. . : *. : * ..:*: *: *******::********:** ***:****:* :*:**************.********************.*****:*********** :*::*********:*******::* **::*****:**** .** :**:**:***:************:*. : ... ::****::********:*** ***:***.* * :::** ***:*********.* :** :: : ..:** ******************************:********************:*********** . :*.*.***********:********* ** : ***********************************: ** :: :*:. * :.. .*. *. ** ..::.* *.*: ::::.: : :.:: * *.: . .. . *. : ***", "identical_positions": 312, "similar_positions": 112, "identity": "47.49%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-16", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P53986-1", "uniprot_id": "MOT1_MOUSE", "id": "P53986-1", "name": "Monocarboxylate transporter 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------MPPAIGGPVG-----------------------------------YTPPDGGWGWAVLVGAFISIGFSYAFPKSITV---FFKEIEVIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYLCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFDIFDWRGSFLILGGLLLNCCVAGSLMRPIG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PEQVKLEKLKSKESLQEAGKS-------DANTDLIGGSPKGEKLSVFQTINKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSSYGKSKDFSSEKSAFLLSILAFVDMVARPSMGLAANTKWIRPRIQYFFAASVVANGVCHLLAPLSTTYVGFCVYAGVFGFAFGWLSSVLFETLMDLIGPQRFSSAVGLVTIVECCPVLLGPPLLGRLN---DMYGDYKYTYWACGVILIIAGIYLFIGMGINYRL-LAKEQKAEEKQKREGKEDEASTDVDEKPKETMKAAQSPQ--QHSSGDPTEEESPV--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P53987-1", "uniprot_id": "MOT1_RAT", "id": "P53987-1", "name": "Monocarboxylate transporter 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------MPPAIGGPVG-----------------------------------YTPPDGGWGWAVVVGAFISIGFSYAFPKSITV---FFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQQGKVEKLKSKESLQEAGKS-------DANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLN---DMYGDYKYTYWACGVILIIAGLYLFIGMGINYRL-VAKEQKAEEK-KRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53985-1", "uniprot_id": "MOT1_HUMAN", "id": "P53985-1", "name": "Monocarboxylate transporter 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------MPPAVGGPVG-----------------------------------YTPPDGGWGWAVVIGAFISIGFSYAFPKSITV---FFKEIEGIFHATTSEVSWISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGALMRPIG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLN---DMYGDYKYTYWACGVVLIISGIYLFIGMGINYRL-LAKEQKANEQ-KKESKEEETSIDVAGKPNEVTKAAESPDQ-KDTDGGPKEEESPV--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F7B3-1", "uniprot_id": "E7F7B3_DANRE", "id": "E7F7B3-1", "name": "Monocarboxylate transporter 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------MAPAVGGPVG-----------------------------------YTPPEGGWGWAVVLGAFISIGFSYAFPKSITV---FFKEIEVIFNATSSQVSWISSIMLAVMYGGGPVSSILVNKYGSRPIMILGGCLSGAGLIAASFCNTVEGLYFCVGVVGGLGLAFNLNPALTMIGKYFYKKRPIANGIAMAGSPVFLSTLAPLNTWFFDQFGWRGSFLILGGLLLNCCVAGSLMRPIG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKP---------QPAVKADNS---------------NSRAKERKTVVEVINGFIDLTLFKHRGFLLYLLGNVVMFFGLFSPLVFLSNYAKSKQIPREKAAFLLSILAFVDMVARPSMGIVANTKWVRPRVQHFFAASILLNGVCHLLAPLSTDYTGFVIYAIFFGFAFGWLSSVLFETLMDLVGAQRFSSAVGLVTIVECGPVLLGPPLLGKFN---DIYHDYKYTYMGCGIVLLIGSLFLFVGMGINYKL-LEREAKEESK--KANQQDDPGKEVVEALK--------------AAEDNAAEEAV---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W509-1", "uniprot_id": "Q9W509_DROME", "id": "Q9W509-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------MVHG---PPARRKSQQQ-------HEACEMDMERQP--------------------------------------TPPDGGWGWVVVFGSFMIHIVTDGMTYSFGI---FYNEFLDYFNEGKGYTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPL----------------------------------------ELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLP---------------------KDQYLQLPQRTDTAVSGGALCRS----NSVGHNLKPNLNNNSN----------GAVNGQGPTLVT------------PPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRE----RSASGTMYRP----DALYQGSLHNLPDYVSS------RNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRIILGYISDKPWVN--RLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMY---DLTDSYAPAFLMAGLMIAISGLVMFAIPPLQRLQ-VRKSERKPHTEHLALS-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W0L6-1", "uniprot_id": "Q9W0L6_DROME", "id": "Q9W0L6-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------MVDTNSSNPGIVGGNSASSARLRRFERTDSELACEEAARLTAEQSPEDEDNQDNDEDDD---------------DEESVYGELPPPPDGGYGWVICFASFMCNMIVDGIAYTFGI---FLEEFVAYFHEGKGTVAWVGSLLSGVYLSAGPIVSALANKYGCRAVCIAGSIIACIAFVLSTFSTNVSMLMATYGFMGGFGFGMIYLPAVVAVGYYFETKRSLATGIAVCGSGFGTFAFAPLATYLLEEYGWKNALLIFAGLILNCAIFGAMMRPLTYPKKKKQKPLMQRMYEEKQLQLERGSFAGSHFMVQLPDGTIERKLKMPLNADPGVHSSLNLELLAQQAGGGGLHPVSTLPTITESKVVDVHRQNGAQSPPNGDSNGQLSARSAAGAVGRRPHRNSESENSPYHSQDAMTRNASQPAFLAGDHQSLPKNGSVPAFNTRVRKTSASERFQPSLAAIRATSRGDLEAGAGGDFASSKLSLSQRQGGSQTGSSGRMVRPMSRKDIFYSGSVTNLPQYQSQKSLANYRNSVLSLTKYEKSMQSVAKLDPLAEAEKHREEYDLCPCLGIPDSVKSVVNTMLDVSLLKDPVFMLIGVSNIFGMAGLYVPFVYLVDAAKEHDIPKNDAAMLLSIIGITNTVGRVFCGWVADLPQVN--SLLLNNCCLLVSTIAVTLTPLCYSYAAYITMSIFFGLAISGYISLTSIILVDLLGLDKLTNAFGLLILFRGFAALIGTPLAGAIY---DMTHTYDLPFYMAGALFGISTITSFLAPCLKRCS-PSE-ETPVHVETLTPIDEEQGEDAEDDEDQPITIVPKIIKTLASPQQEEGHPQFPQKTSESKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53918-1", "uniprot_id": "ESBP6_YEAST", "id": "P53918-1", "name": "Uncharacterized transporter ESBP6", "aln": "MSTHSNDYFSASSGMVSETSSEVSSINSSQPVSFSKASIAAPVPCSDLHSTKSNDASRKLSISRTLTNRLNDIKKAVDDDNLQTEENSADVNKILESRFDVADAIRLQHNESVQSKLNIPVTHTTTAGASLSAPSSSAFSASSIQNDTTEHKASMDSKLMRNRLYPASTKHSGKDLEAQGITEFEPDEPTVKKVFTNKSTGQLELPPDGGYGWVVTFCVFLTMFSTWGCNASFGVDLAYYLNHDTYPGASKYDYALIAGLTVFLGQLLSPLVMALMRIIGLRTTMLFGDAVMLAAYLLASFTTKLWQLYVTQGFMVGCSISLIFVPATTVLPGWFLKKRAVAMGVSLLGTGAGGVVYGLATNKMLSDFGNTRWCLRIIGISCSISVLVAIALLKE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RNPTPAIGLK--------------------SPRAMFEQLKAMFSLKVITKPFVVLIALWFMFALFAYNMMVFTLSSYAISKGLSSHDASTLTAILNGSQSIGRPLMGLAGD-KFGRANVTIVLTTLLTIYMFAFWIP--AHTFVQLIFFSILVGSCVGVANVMNTVLIADMVKPEEFLPAWAFVNYCGAPFLLVCEVIAQALTVEKDKSNPYLHAQIFCGCCFIAALILISILREYSIRMKLTERQAMTNEKLKEWKASEYDTDSADEDWGKLKERKTKYDLLLGPGIKKYFLRMVYPMKV---", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q08268-1", "uniprot_id": "MCH4_YEAST", "id": "Q08268-1", "name": "Probable transporter MCH4", "aln": "----------------------------------------------------------------------------------------------MLNIPIIANSKRFLFSKDHEAQSTRDHDVELETREGPSSGYNPNFNAADAILKKNSDQVDLDVNKLTNVTSRVLNTPEASLIYDD----------------------DREFPDGGLKAWLVVFGAFMGLVPVFGLINSLGA-IESYISKHQLANISSSTISWIFSLYLAISFLSCILSGGYFDRNGSIGLMCTGTVIYAGGLFALANCKSVWQFILAFSVCSGLGTGILMTPLIGTVATWFLKRRGIATSISTMGGSIGGIVFPIMLRKLYKEVGFQWAIRILSFICLTCLICASVLARER----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TKPVVQPFKS--------------------KAEVAKWYISSVFNWRYFLEGKFLFVAIGASFAESSLTSCATYLASYSMTRGNTENVAYTMITASNAVGILGRYIPGYFADKFIGRFNVEIITISMAALFNFVMWLP-FGGNTKVLWAYVCLWGFSTGSILSLTPVCIGQISKTTDFGKRYATVYLLQALVTIPVLPIGGTLIG-KGTVANYNHFIIFNSALMAAGAACYIISRHICVGAKLCKF-----------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * .* : . *: . :: . . : : .: : : * * : . .: : .. * . .: * : :* :* :* .:: * . : . : : . : :: . .:. : . .:: . : . . : : : :.* * .: . . . : . * . : : :: : . : : : : . * . : . . ", "identical_positions": 16, "similar_positions": 82, "identity": "1.66%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-21", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70161-1", "uniprot_id": "PI51C_MOUSE", "id": "O70161-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "aln": "------MELEVPD----------------EAESAEAGAVTAEAAWSAESGAAAGMTQKKAGLAEAPLVTGQPGPG----------------------------------------------------------HGKKLGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDD----YLYSLCNEPLIELSNP---GASGSVFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPR-TLLPKFYGLYCVQSGGKNIRVVVMNNVLPRVVKMHLKFDLKGSTYKRRASKKEKEKSLPTYKDLDFMQDMPEGLLLDSDTFGALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQQERERQAE---GAQSKADEKRPVAQK-----------------------------------------------ALYSTAMESIQGGAARGEAIETDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHT-------WKALVHDGDTVSVHRPSFYAERFFKFMSSTVFRKSS-----SLKSSPSKKGRG-ALLAVKPLGPTAAFSASQIPS-EREDVQYDLRGARSYP-TLEDEGRPDLLPCTPPSFEEATTASIATTLSS----TSLSIPERSPS-DTSEQPRYRRRTQSS-GQDGRP-------------QEEP--HAEDLQKITVQVEP--------------------------VCGVG-VVPK------------------------------EEGAGVEVPPCGASAAASVEID--AASQASEPASQAS-----DEEDAPSTDIYF--------------------------PTDERSWVYSPLHYSAR--PASDGESDT-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5I6B8-1", "uniprot_id": "PI51C_RAT", "id": "Q5I6B8-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "aln": "------MELEVPD----------------EAESAEAGAVTAEAAWSAESGAAAGMTQKKAILAEAPLVTGQPGPG----------------------------------------------------------HGKKLGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDD----YLYSLCNEPLIELSNP---GASGSVFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPR-TLLPKFYGLYCVQSGGKNIRVVVMNNVLPRVVKMHLKFDLKGSTYKRRASKKEKEKSLPTYKDLDFMQDMPEGLLLDSDTFGALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQQERERQAE---GAQSKADEKRPVAQK-----------------------------------------------ALYSTARESIQGGAARGEAIETDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHT-------WKALVHDGDTVSVHRPSFYAERFFKFMSSTVFRKSS-----SLKSSPSKKGRG-ALLAVKPLGPTAAFSASQIPS-EREDVQYDLRGARSYP-TLEDEGRPDLLPCTPPSFEEATTASIATTLSS----TSLSIPERSPS-DTSEQPRYRRRTQSS-GQDGRP-------------QEEL--HAEDLQKITVQVEP--------------------------VCGVGVVVPK------------------------------EQGAGVEVPPSGASAAATVEVD--AASQASEPASQAS-----DEEDAPSTDIYFFAHGRYWLFSPRRRRLRAVTPSHTGAPTDGRSWVYSPLHYSAR--PASDGESDT-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60331-1", "uniprot_id": "PI51C_HUMAN", "id": "O60331-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma", "aln": "------MELEVPD----------------EAESAEAGAVPSEAAWAAESGAAAGLAQKKAAPTEVLSMTAQPGPG----------------------------------------------------------HGKKLGHRGVDASGETTYKKTTSSTLKGAIQLGIGYTVGHLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHFQDFRFKTYAPVAFRYFRELFGIRPDD----YLYSLCNEPLIELSNP---GASGSLFYVTSDDEFIIKTVMHKEAEFLQKLLPGYYMNLNQNPR-TLLPKFYGLYCVQSGGKNIRVVVMNNILPRVVKMHLKFDLKGSTYKRRASKKEKEKSFPTYKDLDFMQDMPEGLLLDADTFSALVKTLQRDCLVLESFKIMDYSLLLGVHNIDQHERERQAQ---GAQSTSDEKRPVGQK-----------------------------------------------ALYSTAMESIQGGAARGEAIESDDTMGGIPAVNGRGERLLLHIGIIDILQSYRFIKKLEHT-------WKALVHDGDTVSVHRPSFYAERFFKFMSNTVFRKNS-----SLKSSPSKKGRGGALLAVKPLGPTAAFSASQIPS-EREEAQYDLRGARSYP-TLEDEGRPDLLPCTPPSFEEATTASIATTLSS----TSLSIPERSPS-ETSEQPRYRRRTQSS-GQDGRP-------------QEEPP-AEEDLQQITVQVEP--------------------------ACSVEIVVPK------------------------------EEDAGVEASPAGASAAVEVETASQASDEEGAPASQAS-----DEEDAPATDIYF--------------------------PTDERSWVYSPLHYSAQAPPASDGESDT-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G7V2-1", "uniprot_id": "A0AC58G7V2_DANRE", "id": "A0AC58G7V2-1", "name": "", "aln": "------MEAAAAG----------------GCS-ALAEDADAVLGCGMEP-AEIEAALKKTCLSEMPSSSCHSSSG----------------------------------------------------------PEKKIGHRRVDASGETTYKKTTSSALKGAIQLGIGYTVGNLSSKPERDVLMQDFYVVESIFFPSEGSNLTPAHHYPDFRFKTYAPVAFRYFRELFGIRPDD----YLYSLCNEPLIELSNP---GASGSIFYVTRDDEFILKTVMHKEAEFLQKLLPGYYMNLNQNPR-TLLPKFFGLYCVQSGGKNIRIVVMNNVLPRVFRMHLKFDLKGSTYKRRASKKEREKNRPTYKDLDFMQDVQDGLLLDVDTYNALLKTLQRDCLVLESFKIMDYSLLLGVHNVEQAERERQME---GSQGS-DEKRPAAQR-----------------------------------------------ALYSTAMESIQGGAACGDSIDTDDTMGGIPAVSGKGERLLLFIGIIDILQSYRLIKKLEHT-------WKALVHDGDTVSVHRPNFYADRFFRFMSANVFKKST-----SLKASPAKKGRS-VLAVPKFSVPGAAWSASQLPS-ERDENIYDLRGARSFP-VLENDG---LQSCTPPSFEEATTASVATTLSSN---TSISIPERSPS-DTSEHPRYRRHTLSLKDAEGRT-------------HEVVDVHEEDQQTITVQVEVKRETEEDEDDRETDASQTHTDPETHIAAETEMVPPPPADSDPADDLETQTASSAPDDQENPPPADSEQQTAADPPEAESRSAESAEANPQTQLPPADPLSQSQSRESLEEELAANTDIYFVSRIMTG---------GCYFDFSCVSIRVVTIYRYDGLPRFERARLSYHEQLHINGFNP------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2R3-1", "uniprot_id": "PI5K1_DROME", "id": "Q9W2R3-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase type-1 sktl", "aln": "MDTRVELELEPVGKQDRLKDQPDDENEPLENQLELEQEHKSLLTPVKIPPAQTASPDQEATPSTPPPMSLQPGTSRQLFRDAAMAHGGQETTSLLQQELNNIAATQTPASKLRSASSTLDASISRNPSTTGGKHEKKLGHRRVAEGGEVTYKKIQSKQIMGSIQLGIQHTVGSLASKPKRDLLMNDFWEMETISFPPDGSSITPAHHYNDFRFKVYAPIAFRYFRDLFGIAPDD----FLMSMCASPLRELSNP---GASGSIFYLTTDDEFIIKTVQKKECEFLQKLLPGYYMNLSQNPR-TLLPKFFGLYCFHYNSKNVRLVAMNNLLPSDIKMHCKYDLKGSSFRRKASKAERQKASPTFKDLDFAEHHPNGIFLETDKYNALMSTIKRDCMVLESFQIMDYSLLVGIHNLDLAAKEKREERILNARAKLQRKESAAQGPPSLNPDDDAPEADQNQLQAVASYASIPGTSAGAALNRTRSMNRQRLVAHSTALESITADMDVPLEEDEDVPAGGIPARSENDERLILYIGIIDILQSYRLEKKLEHT-------FKSILYNGDTVSVCRPSFYAKRFQDAMGKQVFKKTPT---FPLKHSPSKRKTS----TTQLRSPASRLPPLSTPTNAVRQPIMTMSGMSTPPPAFDDISEEDITAASTSSLQQQRSSNQSNNNRGE---TEVALREGNNTRGGSGEPSSTYHTQYSYDSSGRT-------------GSALTSDYSDDESTGTDLSSR-----------------LPKLRTHRLTKTSVQVTT-----------------------------VGYVEGVDTPPKGGQDVVHADVNGKTTMTTTTMLTTTK--------TAHIQA-----------------------------PSYTSTLVLNDLPR-------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38994-1", "uniprot_id": "ITS3_YEAST", "id": "P38994-1", "name": "Phosphatidylinositol 4-phosphate 5-kinase MSS4", "aln": "------MSVLRSQP---------------PSVVPLHLTTSTSRKTEQEPSLLHSAIIERHQDRSVPNSNSNPDSN---------------------------------------------------------HRIKKDRNNHTSYHSSSNSESNMESPRLSDGESSTPTSIEELNPTINNSRLVKRNYSISIDPLHDNSNNNTDDDHPNTITSPRPNSTSNKEMQKYSFPEGKESKKITTPSLNSNNCLDLDNSSLVHTDSYIQDLNDDHILLNKRVSRRSSRISAVTATSTTIKQRRNTQDSNLPNIPFHASKHSQILPMDDSDVIKLANGDTSMKPNSATKISHSMTSLPLHPLPQPSQKSKQYHMISKSTTSLPPENDHYYQHSRGTNHNHAANAAAVNNNTTTTTAATGLKRSESATAEIK--KMRQSLLHKREMKRKRKTFLVDDDRVLIGNKVSEGHVNFIIAYNMLTG----------IRVAVSRCSGIMKPLTPADFRFTKKLAFDYHGNELTPSSQYAFKFKDYCPEVFRELRALFGLDPADYLVSLTSKYILSELNSPGKSGSFFYYSRDYKYIIKTIHHSEHIHLRKHIQEYYNHVRDNPNTLICQFYGLHRVKMPISFQNKIKHRKIYFLVMNNLFPPHLDIHITYDLKGSTWGRFTNLDKERLAKDRSYRPVMKDLNWLEEGQKIKFGPLKKKTFLTQLKKDVELLAKLNTMDYSLLIGIHDINKAKEDDLQLADTASIEE-----------------QPQTQGPIRTGTGTVVRHFFR---------------------------EFEGGIRASDQFNNDVDLIYYVGIIDFLTNYSVMKKLETFWRSLRHDTKLVSAIP-------------------------PRDYANRFYEFIEDSVDPLPQKKTQSSYRDDPNQKNYKD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : . :. . :.... ** :. . .. . :. .. . : . :: * .. :.. *:: : :. : :... * .* : . : : ::. .: *: . :*.*. :.. : :. *. :: * * ::...: .. :: :*.: : **:: . : : : :: *: : * * . : . *: .: .. .: : * : ::: . : : : . .:. : . .*. : . .:. . . * : : ::::. * *: : * :: : :: . . ** .* : :.:. :: : . : . . . : * :: : .: : : . :. ..: * . . . * . . . . .* : . . . . . . : ", "identical_positions": 32, "similar_positions": 184, "identity": "3.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-26", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q810J1-1", "uniprot_id": "PSG22_MOUSE", "id": "Q810J1-1", "name": "Pregnancy-specific glycoprotein 22", "aln": "MEVSSELLS-NGWTSWQRVLLTASLLTCWLLPITAGVT-IESVPPKLVEGENVLLRVDNLPENLRVFVWYRG-VTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHS---------GREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPS---------KCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9Q6J6-1", "uniprot_id": "E9Q6J6_MOUSE", "id": "E9Q6J6-1", "name": "", "aln": "MEVSSELLLSNGCTSRQRVLLTASLFTCWLLSTTAKVT-IHS-PLQVVEGQNVFLRVDNLPEDLLAFAWYRG-LRNWRVAIALHLVEYNASMTGPEHSDREILHSNGSLWIQNVTQEDTGYYTLQTISKHGKLVSNTSTFLQVYSALFTCGRPTSPAKLTIESVPPRVAEGGSVLLLVHNLPEYSQLFSWYKGLTLFNEVEIAEYKIAKNLSDPGPAHSGREIVFSNGSLLLQNVTWKDTGFYTLQTVNGFREMELAHIYLRVDT---PCCDPPDSARLRIDPVTCHAAEGGSVLLQVHNLPEDVQTFSWYKGVDSTPYFRIVEYSKAMKSIFSGYAHS---------RRETGYTNGSLLLQDVTEKDTGFYTLLTIDSHVKVETVHAQVNVHKLVTQPVVRVTDSTVRVQSSVVFTCFSDNTGVSIRWLFNNQSLQLTERMTLSPS---------KCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVSLAVMNE-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q61400-1", "uniprot_id": "CEAMA_MOUSE", "id": "Q61400-1", "name": "Cell adhesion molecule CEACAM10", "aln": "MELASAHLH-KGQVPWVGLLLTASLLTYWSPATTAQVT-VEAVPPNVTADNNVLLLVHNLPQTLRVFYWYKGNSGAGHNEIGRFVTSINRSKMGLAHSGRETIYSNGSLFFQSVTKNDEGVYTLYMLDQNFEITP-ISVRFHVHPSLLPSLSPPTTGQVTVEAVPPNVAEGENVLLLVHNLPRTLRAIYWYRGTTAGERNEIARFITASNKIILGPAHSDREIIYNNGSLFFQGVTKNDEGAYALDML------------------------------------------------------------------------------------FQNFDH----------------------------------TLMPVQFNVHAKKQ---------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB14YBK9-1", "uniprot_id": "A0AB14YBK9_DANRE", "id": "A0AB14YBK9-1", "name": "", "aln": "--------------------MRVFIWILWSVIFISGVSDAAADEVSVMEGESATLNAGIVKTQKDRIRWYFNGSRIAELNGDQVKICVDDVCPDRFRGRLQLDNTSGSLIVTNTRKTDSGLYQLQINSRR----TEKKFILSVQGALGADTPESS----------VSVMEGDSVTLCTGVQTNQSNRIKWYFYTDRIAEIIGYQHKICTDDTCPQRFRDRLKLDSQTGSLTIMKVSTEDSGLYTFLHRGREKIFRVVILALKNLKQKSATEGESITLDTPIKTTPNDVLKWYFGEILLAELTGGASQICEDAQCKDGFRDRLKVNHSSGSLTIMNSSKADSGEYTLLINSSSFYINGSFTVSVASVLGLSLSTGIGICAGVLLVLLTVGATAFYFTIKMVKKRSKDKVKPFTLPCDNRPRDQGKSKQVNGNGMKQINQIDETDFQPTNFATESFHVEEETRSTTSSNQTSNNQEHIPFIDEEPEDEYKPGIPVIQPEKGVILE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : * : *: : .: .:.. * . : : ** . . . :. : .*** . .. : * * * * .:. . . : * :* .. * ** .* * . . . : ** . .. .: . :: ..*** : *: :* * *:: : . : * : : * ", "identical_positions": 30, "similar_positions": 60, "identity": "5.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-27", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8WXD0-1", "uniprot_id": "RXFP2_HUMAN", "id": "Q8WXD0-1", "name": "Relaxin receptor 2", "aln": "MIVFLVFKHLFSLRLITMFFLLHFIVLINVKDFALTQGSMITPSCQKGYFPCGNLTKCLPRAFHCDGKDDCGNGADEENCGDTSGWATIFGTVHGNANSVALTQECFLKQYPQCCDCKETELECVNGDLKSVPMISNNVTLLSLKKNKIHSLPDKVFIKYTKLKKIFLQHNCIRHISRKAFFGLCNLQILYLNHNCITTLRPGIFKDLHQLTWLILDDNPITRISQRLFTGLNSLFFLSMVNNYLEALP-KQMCAQMPQLNWVDLEGNRIKYLTNSTFLSCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNTITELSPHLFKDLKLLQKLNLSSNPLMYLHKNQFESLKQLQSLDLERIEIPNINTRMFQPMKNLSHIYFKNFRYCSYAPHVRICMPLTDGISSFEDLLANNILRIFVWVIAFITCFGNLFVIGMRSFIKAENTTHAMSIKILCCADCLMGVYLFFVGIFDIKYRGQYQKYALLWMESVQCRLMGFLAMLSTEVSVLLLTYLTLEKFLVIVFPFSNIRPGKRQTSVILICIWMAGFLIAVIPFWNKDYFGNFYGKNGVCFPLYYDQTEDIGSKGYSLGIFLGVNLLAFLIIVFSYITMFCSIQKTALQTTEVRNCFGREVAVANRFFFIVFSDAICWIPVFVVKILSLFRVEIPDTMTSWIVIFFLPVNSALNPILYTLTTNFFKDKLKQLLHKHQRKSIFKIKKKSLSTSIVWIEDSSSLKLGVLNKITLGDSIMKPVS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91ZZ5-1", "uniprot_id": "RXFP2_MOUSE", "id": "Q91ZZ5-1", "name": "Relaxin receptor 2", "aln": "-----------------MWLLLHVILLTEVKDFALADSSMVAPLCPKGYFPCGNLTKCLPRAFHCDGVDDCGNGADEDNCGDTSGWTTIFGTVHGNVNKVTLTQECFLSQYPQHCYCRENELECVKADLKAVPKVSSNVTLLSLKKNKIHRLPVKVFSRYTELRKIYLQHNCITHISRRAFLGLHNLQILYLSHNCITSLRPGIFKDLHQLAWLILDDNPITRISQKSFMGLNSLFFLSMVGNRLEALP-ETLCAQMPQLNWVDLANNGIKYITNSTFLTCDSLTVLFLPRNQIGFVPEKTFSSLKNLGELDLSSNMITKLPVHLFSDLHLLQKLNLSSNPLLYVHKNQFGSLKQLQSLDLERIEIPNISTGMFQPMKNLSHIYLKTFRYCSYVPHVRICMPSTDGISSSEDLLANGILRVSVWVIAFITCVGNFLVIAVRSLIKAENTTHAMSIKILCCADCLMGVYLFSVGVFDIKYRGQYQKYALLWMESVPCRLLGFLATLSTEVSVLLLTFLTLEKFLVIVFPFSNLRLGKRQTAVALASIWVVGFLIAAVPFTREDYFGNFYGKNGVCFPLHYDQAEDFGSRGYSLGIFLGVNLLAFLVIVISYVTMFCSIHKTALQTAEVRSHIGKEVAVANRFFFIVFSDAICWIPVFVVKILSLLQVEIPGTITSWIVVFFLPVNSALNPILYTLTTSFFKDKLKQLLHKHRRKPIFKVKKKSLSASIVWTDESS-LKLGVLSKIALGDSIMKPVSP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F8W5N7-1", "uniprot_id": "F8W5N7_DANRE", "id": "F8W5N7-1", "name": "", "aln": "------MRSLQSAATASALELCLILFTTSITTAKAGQEHRPSEDCPLGHFPCGNVSICLPQVLHCNNQKDCPNGADEDNCGDNSGWADLFDRTFKRGYLQELATDCQVEQYPDVCRCINTEIHCVHASLRSIPQVSANVTSLSLKSNKIRTLPDEAFIKYIKLQRLFLQDNCINTVSIQAFSGLYKLQKLSLSQNSISLLSPGVFRDLRKLKWLILDDNPITTIAANTFAGLSSLFFLSMVNTSLEALPSARLCAHMPFLSWLDFEGNSITTLGLSTLLDCEHLTVLSLRANLIKSLPENTFQSLRMMGDLDLSNNSIKELPVGIFKDLRSLQSLNLSQNPLDHIHPGQFNHLIQLQSLGLEGVEIPNIQTSMFRPMDNLSYIYFKKFQYCSYAPHVRKCKPNSDGLSSFEDLLANVVLRVSVWVMAFITCFGNLFVIGMRTVLRAENNLHAFCIKVLCCADCLMGVYLFFVGIFDVKFRGEYNKNAKVWMESLECRTIGFLAMLSSEVSVMLLTYLTLEKFLVIVFPFSHLRPSKCQTFTVLVSIWLLGISIAAVPLLNEDTFGNYYGLNGVCFPLHSERLEKPVAKGYSTGIFLGLNLLAFLIIVVSYSSMFYSIYKTGIRATELPGRLHRDVAMAHRFFFIVFSDALCWIPIFMVKILSLLEVEIPGTITSWVVIFILPINSALNPILYTLTTSFFREQVEHLWGHWQRQPRLKQGRKSLTSSVIYMDPSR-PSFYHRSYIPHSSILDIDASYR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .:. .:. : : * *:*****:: ***:.:**:. .** *****:****.***: :*. .. . *: :* :.***: * * :.*:.**:..*:::* :* *** ****.***: ** :.* :* :*::::**.*** :* :** ** :** * *.:*.*: * **:*:**::* ********** *: . * **.********.. ***** :**:** *.*:*: .* *. : **:* *: **** * * * :**:**.**: :*:****.* *.:*. :*.**: **.****.*** ::* .** * *****.** :*****.* **:**.***:**:*.*:****.**** * * :**:** ****** :**: ***:*****.**::**.:*:.::***. **:.**:************* **:**:*:**:*:* * :****: ** :**** **:****:***:**************::* .* ** . * .**: *: **.:*: .:* ***:** *******: :: *. ::*** *****:******:**.** :** ** **.::::*: . : ::**:*:**********:****:*:******:.****.*:***:*:*:**:*************.**::::::* : :*:. :* :***::*::: : * .: . *. .. : .* ", "identical_positions": 389, "similar_positions": 208, "identity": "51.39%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-28", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55083-1", "uniprot_id": "MFAP4_HUMAN", "id": "P55083-1", "name": "Microfibril-associated glycoprotein 4", "aln": "MKALLALPLLLLLS--TPPCAPQVSGIRGDALERFCLQQPLDCDDIYAQGYQSDGVYLIYPSGPSVPVPVFCDMTTEG-----GKWTVFQKRFNGSVSFFRGWNDYKLGFGRADGEYWLGLQNMHLLTLKQKYELRVDLEDFENNTAYAKYADFSISPNAVSAEEDGYTLFVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRSCHFANLNGFYLGGSHLS-YANGINWAQWKGFY-YSLKRTEMKIRRA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D1H9-1", "uniprot_id": "MFAP4_MOUSE", "id": "Q9D1H9-1", "name": "Microfibril-associated glycoprotein 4", "aln": "MKALPALPLMLMLLSMPPPCAPQASGIRGDALEKSCLQQPLDCDDIYAQGYQEDGVYLIYPYGPSVPVPVFCDMTTEG-----GKWTVFQKRFNGSVSFFRGWSDYKLGFGRADGEYWLGLQNLHLLTLKQKYELRVDLEDFENNTAYAKYIDFSISPNAISAEEDGYTLYVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRSCHFANLNGFYLGGSHLS-YANGINWAQWKGFY-YSLKRTEMKIRRA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F8W539-1", "uniprot_id": "F8W539_DANRE", "id": "F8W539-1", "name": "", "aln": "MMASMVFLVALLSIVLVNGCSEDED-------------SPVDCSDLKKAGETLSGVYTIHPAG-ETPVWVYCQMVSDGKDEENGGWTVFQRRMDGSVNFYRPWRDYKRGFGNVEGEYWLGLENLYQLTRHKKFMLRVDLEDFTGRKGFAQYSSFSVG-----CETDGYKLQVSGFKDGGAGDSMTYHNGMKFSTFDKDQDNFDKSCARLYLGAFWYNNCHHANLNGVYLWGEDATIFAIGNVWYGWKSNYGIGMKSITMKIKHVP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * .: : *: *: : . .*:**.*: * .*** *:* * ..** *:*:*.::* * *****:*::***.*:* * *** ***..:*******:*:: ** ::*: ******** ....:*:* .**:. .* ***.* *:**:*******::**.* ******:*** * :.** * ****:..**.*****.** *.. : :* * * **. * .:* ***::. ", "identical_positions": 118, "similar_positions": 68, "identity": "44.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-31", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88302-1", "uniprot_id": "GNA15_RAT", "id": "O88302-1", "name": "Guanine nucleotide-binding protein subunit alpha-15", "aln": "----MAR-SLTWGCCPWCLTEEEK-----------TAARIDQEINKILLEQKKQER-----------------------------------------------------------------GELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEDRRAFRLLVYQNIFVSMQAMIEAMDRLQIPFSRPDSKQHASLVMTQ---------------------------------------------------------------------------------------------------------------DPYKVSSFEKPYAVAMQYLWR-DAGIRACYE-RRREFHLLDSAVYYLSHLERIAEDDYIPTAQDVLRSRMPTTGINEYCFSVQ-KTKLRIVDAGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENSQENRMKESLALFSTILELPWFKSTSVILFLNKTDILEDKIHTSHLASYFPSFQGPRRDAEAAKRFILDMYAR-VYASCAEPHDGGRKGSRARRLFAHFTCATDTHSVRSVFKDVRDSVLARYLDEINLL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P30678-1", "uniprot_id": "GNA15_MOUSE", "id": "P30678-1", "name": "Guanine nucleotide-binding protein subunit alpha-15", "aln": "----MAR-SLTWGCCPWCLTEEEK-----------TAARIDQEINRILLEQKKQER-----------------------------------------------------------------EELKLLLLGPGESGKSTFIKQMRIIHGVGYSEEDRRAFRLLIYQNIFVSMQAMIDAMDRLQIPFSRPDSKQHASLVMTQ---------------------------------------------------------------------------------------------------------------DPYKVSTFEKPYAVAMQYLWR-DAGIRACYE-RRREFHLLDSAVYYLSHLERISEDSYIPTAQDVLRSRMPTTGINEYCFSVK-KTKLRIVDVGGQRSERRKWIHCFENVIALIYLASLSEYDQCLEENDQENRMEESLALFSTILELPWFKSTSVILFLNKTDILEDKIHTSHLATYFPSFQGPRRDAEAAKSFILDMYAR-VYASCAEPQDGGRKGSRARRFFAHFTCATDTQSVRSVFKDVRDSVLARYLDEINLL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30679-1", "uniprot_id": "GNA15_HUMAN", "id": "P30679-1", "name": "Guanine nucleotide-binding protein subunit alpha-15", "aln": "----MAR-SLTWRCCPWCLTEDEK-----------AAARVDQEINRILLEQKKQDR-----------------------------------------------------------------GELKLLLLGPGESGKSTFIKQMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQ---------------------------------------------------------------------------------------------------------------DPYKVTTFEKRYAAAMQWLWR-DAGIRACYE-RRREFHLLDSAVYYLSHLERITEEGYVPTAQDVLRSRMPTTGINEYCFSVQ-KTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQCLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQGPKQDAEAAKRFILDMYTR-MYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVRDSVLARYLDEINLL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RS61-1", "uniprot_id": "A0A8M1RS61_DANRE", "id": "A0A8M1RS61-1", "name": "", "aln": "----MGHYYYTCPCIVWFLSEEEK-----------NAIDINNEIKRILQEQKKQQR-----------------------------------------------------------------KEIKVLLLGSGESGKTTFLKQMRIIHGQGFSDDERHVFTKLVYQNIFKSMQAMTEAMSELKIPYANPQSEVYATWFQDQ---------------------------------------------------------------------------------------------------------------DPHKITKLQRSYVEAIRHLWA-DKGIKSCYS-RRREYQLLDSTKYFLSNLDRIAADIYIPTNQDILQVRFPTSGITDHSFNFE-KMILRIVDVGGQRGQRKKWIHCFENVTSLIFVASLSEYDQRLEENNKDNRMLESLSLFYTTIHSKWFAYSSVILFLNKIDILEEKIQFSNLKSYFPEFKGKPRNGQDAIQFIKELYTHNAYSSETKS---------SKNVYFHYTCATDTNNIRSVFSDVKDILLLKALQDFEMA-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P08539-1", "uniprot_id": "GPA1_YEAST", "id": "P08539-1", "name": "Guanine nucleotide-binding protein alpha-1 subunit", "aln": "---------MGCTVSTQTIGDESDPF--------LQNKRANDVIEQSLQLEKQRDK-----------------------------------------------------------------NEIKLLLLGAGESGKSTVLKQLKLLHQGGFSHQERLQYAQVIWADAIQSMKILIIQARKLGIQLDCDDPINNKDLFACKRILLKAKALDYINASVAGGSDFLNDYVLKYSERYETRRRVQSTGRAKAAFDEDGNISNVKSDTDRDAETVTQNEDADRNNSSRINLQDICKDLNQEGDDQMFVRKTSREIQGQNRRNLIHEDIAKAIKQLWNNDKGIKQCFA-RSNEFQLEGSAAYYFDNIEKFASPNYVCTDEDILKGRIKTTGITETEFNIG-SSKFKVLDAGGQRSERKKWIHCFEGITAVLFVLAMSEYDQMLFEDERVNRMHESIMLFDTLLNSKWFKDTPFILFLNKIDLFEEKVKSMPIRKYFPDYQGRVGDAEAGLKYFEKIFLS--------------LNKTNKPIYVKRTCATDTQTMKFVLSAVTDLIIQQNLKKIGII-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P10823-1", "uniprot_id": "GPA2_YEAST", "id": "P10823-1", "name": "Guanine nucleotide-binding protein alpha-2 subunit", "aln": "MGLCASSEKNGSTPDTQTASAGSDNVGKAKVPPKQEPQKTVRTVNTANQQEKQQQRQQQPSPHNVKDRKEQNGSINNAISPTATANTSGSQQINIDSALRDRSSNVAAQPSLSDASSGSNDKELKVLLLGAGESGKSTVLQQLKILHQNGFSEQEIKEYIPLIYQNLLEIGRNLIQARTRFNVNLEPECELTQQDLSRTMS-----------------------------------------------------------------------------------------------------------YEMPNNYTGQFPEDIAGVISTLWALPSTQDLVNGPNASKFYLMDSTPYFMENFTRITSPNYRPTQQDILRSRQMTSGIFDTVIDMGSDIKMHIYDVGGQRSERKKWIHCFDNVTLVIFCVSLSEYDQTLMEDKNQNRFQESLVLFDNIVNSRWFARTSVVLFLNKIDLFAEKLSKVPMENYFPDYTGG-SDINKAAKYILWRFVQ--------------LNRANLSIYPHVTQATDTSNIRLVFAAIKETILENTLKDSGVLQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :: :*:::: *:*:****.*****:*.::*::::* *:*.:: : ::: : : : : .: : : . . .: ** . :: * .*: *::.:: ::: * * :*:*: * *:** : :.. . ::: *.***:.:*:******:.: ::: ::***** * *:.. **: **: ** . :. ** :..:***** *:: :*: : .***.: * : : . :: : .: : * **** .:: *: : : :: . *.. : ", "identical_positions": 74, "similar_positions": 119, "identity": "12.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-34", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91YE3-1", "uniprot_id": "EGLN1_MOUSE", "id": "Q91YE3-1", "name": "Egl nine homolog 1", "aln": "MASDSGGPGVLSASERDRQYCELCGKMENLLRCGRCRSSFYCCKEHQRQDWKKHKLVCQGGE-------APRAQPAPAQPRVAPPPGGAPGAARAGGAARRGDSAAASR----VPGPEDAAQARS-------GPG-----PAEPGSEDPPLSRSPGPERASLCPAGGGPGEALSPGGGLRPNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGRETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDQITWIEGKEPGCETIGLLMSSMDDLIRHCSGKLGNYRINGRTKAMVACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKFDRLLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLT--GEKGVRVELK--PNSVSKDV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZT9-1", "uniprot_id": "EGLN1_HUMAN", "id": "Q9GZT9-1", "name": "Egl nine homolog 1", "aln": "MANDSGGPGGPSPSERDRQYCELCGKMENLLRCSRCRSSFYCCKEHQRQDWKKHKLVCQGSEGALGHGVGPHQHSGPAPPAAVPPPRAGAREPRKAAARRDNASGDAAKGKVKAKPPADPAAAASPCRAAAGGQGSAVAAEAEPGKEEPPARSSLFQEKANLYPPSNTPGDALSPGGGLRPNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYKINGRTKAMVACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKFDRLLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLT--GEKGVRVELNKPSDSVGKDVF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F518-1", "uniprot_id": "E7F518_DANRE", "id": "E7F518-1", "name": "hypoxia-inducible factor-proline dioxygenase", "aln": "MEK---CPTVLDP-DGDKQYCELCGKMENLLKCGRCRISFYCSKEHQKEHWKKHKLTCREAD---------KHNTVPQTQQQHP--------------------------------------------------------------------KTAHPEKNNLICSS---------EADLKAKPHTQ-----KLATDYIIPCMNKHGICVVDNFLGEDMGLSILEDVKALHQTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCEKICFLMSRMDDLVRNCNGKLGNYIINGRTKAMVACYPGKGTGYVRHVDNPNGDGRCVTCIYYLNKNWDAKEHGGMLRIFPEGKAQFADIEPKFDRLLLFWSDRRNPHEVQPAYSTRYAITVWYFDADERARAKEKYLTGAGEKGVKVELNKPSEPS-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . * .. : *:*************:*.*** ****.****::.******.*: .: : :. * * : *: .* .. ..*:.: :*: *** :**:************:***.: * .* ::*:***:***********************:************.* :*** ****:*:*.****.* **************:**************************:**** **:**********************:***************:******************* **** *****:***: .:. ", "identical_positions": 231, "similar_positions": 57, "identity": "53.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-35", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55083-1", "uniprot_id": "MFAP4_HUMAN", "id": "P55083-1", "name": "Microfibril-associated glycoprotein 4", "aln": "MKALLALPLLLLLS--TPPCAPQVSGIRGDALERFCLQQPLDCDDIYAQGYQSDGVYLIYPSGPSVPVPVFCDMTTEG-----GKWTVFQKRFNGSVSFFRGWNDYKLGFGRADGEYWLGLQNMHLLTLKQKYELRVDLEDFENNTAYAKYADFSISPNAVSAEEDGYTLFVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRSCHFANLNGFYLGGSHLS-YANGINWAQWKGFY-YSLKRTEMKIRRA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D1H9-1", "uniprot_id": "MFAP4_MOUSE", "id": "Q9D1H9-1", "name": "Microfibril-associated glycoprotein 4", "aln": "MKALPALPLMLMLLSMPPPCAPQASGIRGDALEKSCLQQPLDCDDIYAQGYQEDGVYLIYPYGPSVPVPVFCDMTTEG-----GKWTVFQKRFNGSVSFFRGWSDYKLGFGRADGEYWLGLQNLHLLTLKQKYELRVDLEDFENNTAYAKYIDFSISPNAISAEEDGYTLYVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRSCHFANLNGFYLGGSHLS-YANGINWAQWKGFY-YSLKRTEMKIRRA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1RA44-1", "uniprot_id": "F1RA44_DANRE", "id": "F1RA44-1", "name": "", "aln": "MMMTSMVFLVALLS------IVLVNGCSEDE------DSPVDCSELNKAGETLSGVYTIHPAG-DAPVWVYCQMVSDGKDEENGGWTVIQRRMDGSVNFYRPWRDYKRGFGNLEGEYWLGLENLYQLTRHKDHMLRVDLEDFEGRKGFAQYSSFSVG-----CETDGYQLQVSGFTDGGAGDSMTYHNGMKFSTFDKDQDNFDKSCARLYLGAFWYDNCHHANPNGVYLWGEDATIFAIGNVWYGWKNNYGIGMKSITMKIKHVP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : *: :* ..* * :.*:**.:: * .*** *:* * ..** *:*:*.::* * ***:*:*::***.*:* * *** ***. :*******:*:: ** ::.: *********....:*:* .**:. .* *** * *:** *******::**.* ******:*** * :.** * ****: .**.** **.** *.. : :* * * **. * .:* ***::. ", "identical_positions": 116, "similar_positions": 66, "identity": "43.77%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-37", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23606-1", "uniprot_id": "TGM1_RAT", "id": "P23606-1", "name": "Protein-glutamine gamma-glutamyltransferase K", "aln": "---MEGPRSD--VGRWG-----RSPWQP-TTPSPEPEPEPEPDRSSRSRRGGGRSFWARCCG-----------CCSCGN--------RADDDWGPEPSGSRSRGTSSRGGGSRGGDSRGRDSRGG--RRPESRGSGVNAAGDGTIR--------------------EGMLVVNGVDLLCSR-SDQNRREHHTDEFEYDELILRRGQPFHIILFLNREYE-SSDRIALELLIGNNPEVGKGTHVIIP-VGKGGSG------GWKAQVTKTNGHNLTLRVHTSPNAIIGKFQFTVRTRSEAGEFQLPFDPRNEIYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQFDHGVLDACLYILDRRG-MPYGGRGDPVSVSRVVSAMVNSLDDNGVLIGNWTGDYSRGTNPSAWVGSVEILLSYLRTG-YSVPYGQCWVFAGVTTTVLRCLGLATRTVTNFNSAHDTDTSLTMDIYFDENMKPLEHLNHDSVWNFHVWNDCWMKRPDLPS----GFDGWQVVDATPQETSSGIFCCGPCSVESIKNGLVYMKYDTPFIFAEVNSDKVYWQRQDDG-SFKIVYVEEKAIGTLIVTKAINSNMREDITHIYKHPEGSEAERKAVEKAAAHGSKPN-VYATRDSAEDVAMQVEAQD--AVMGQDLTVSVVLTNRG-SSRRTVKLHLYLCVTYYTGVSGPTFKETKKEVVLAPGASDTVAMPVAYKEYKPHLVDQGAMLLNVSGHVKESGQVLAKQHTFRLRTPDLSLTLLGAAVVG-QECEVQIVFKNPLPITLTNVVFRLEGSGLQRPKVLNVGDIGGNETVTLRQTFVPVRPGPRQLIASLDSPQLSQVHGVIQVDVAPSSG-GRGFSEAVGDSRSGENIPMAFRGGA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLF6-1", "uniprot_id": "TGM1_MOUSE", "id": "Q9JLF6-1", "name": "Protein-glutamine gamma-glutamyltransferase K", "aln": "---MEGPRSD--VGRWG-----RSPWQPPTTPSPEPEPEPEPDRRSRSRRGGGRSFWARCCG-----------CCSCGN--------RGDDDWGPEPSGSRSRGTSSRG----------RDSRGG--RRPESRGSGVNAAGDGTIR--------------------EGMLVVTGVDLLCSR-SDQNRREHHTDEFEYDELIVRRGQPFHMILFLNREYE-SSDRIALELLIGSNPEVGKGTHVIIP-VGKGGSG------GWKAQVTKNNGHNLNLRVHTSPNAIIGKFQFTVRTRSEAGEFQLPFDPRNEIYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQFDHGVLDACLYILDRRG-MPYGGRGDPVSVSRVVSAMVNSLDDNGVLIGNWTGDYSRGTNPSAWVGSVEILLSYLRTG-YSVPYGQCWVFAGVTTTVLRCLGFATRTVTNFNSAHDTDTSLTMDIYFDENMKPLEHLNHDSVWNFHVWNDCWMKRPDLPS----GFDGWQVVDATPQETSSGIFCCGPCSVESVKNGLVYMKYDTPFIFAEVNSDKVYWQRQDDG-SFKIVYVEEKAIGTLIVTKAIHSNNREDITHIYKHPEGSEAERRAVEKAAAHGSKPN-VYATRDSAEDVAMQVEAQD--AVMGQDLAVSVVLTNRG-SSRRTVKLHLYLCVTYYTGVSGPTFKEAKKEVTLAPGASDSVTMPVAYKEYKPHLVDQGAMLLNVSGHVKESGQVLAKQHTFRLRTPDLSLTLLGAAVVG-QECGVQIVFKNPLPVTLTNVVFRLEGSGLQRPKVLNVGDIGGNETVTLRQTFVPVRPGPRQLIASLDSPQLSQVHGVIQVDVAPASG-GSGFSDAGGDSRSGENIPMAYRGGA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22735-1", "uniprot_id": "TGM1_HUMAN", "id": "P22735-1", "name": "Protein-glutamine gamma-glutamyltransferase K", "aln": "--MMDGPRSD--VGRWG-----GNPLQPPTTPSPEPEPEPD----GRSRRGGGRSFWARCCG-----------CCSCRN--------AADDDWGPEPSDSRGRGSSSGT--------RRPGSRGSDSRRPVSRGSGVNAAGDGTIR--------------------EGMLVVNGVDLLSSR-SDQNRREHHTDEYEYDELIVRRGQPFHMLLLLSRTYE-SSDRITLELLIGNNPEVGKGTHVIIP-VGKGGSG------GWKAQVVKASGQNLNLRVHTSPNAIIGKFQFTVRTQSDAGEFQLPFDPRNEIYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQFDHGVLDACLYILDRRG-MPYGGRGDPVNVSRVISAMVNSLDDNGVLIGNWSGDYSRGTNPSAWVGSVEILLSYLRTG-YSVPYGQCWVFAGVTTTVLRCLGLATRTVTNFNSAHDTDTSLTMDIYFDENMKPLEHLNHDSVWNFHVWNDCWMKRPDLPS----GFDGWQVVDATPQETSSGIFCCGPCSVESIKNGLVYMKYDTPFIFAEVNSDKVYWQRQDDG-SFKIVYVEEKAIGTLIVTKAISSNMREDITYLYKHPEGSDAERKAVETAAAHGSKPN-VYANRGSAEDVAMQVEAQD--AVMGQDLMVSVMLINHS-SSRRTVKLHLYLSVTFYTGVSGTIFKETKKEVELAPGASDRVTMPVAYKEYRPHLVDQGAMLLNVSGHVKESGQVLAKQHTFRLRTPDLSLTLLGAAVVG-QECEVQIVFKNPLPVTLTNVVFRLEGSGLQRPKILNVGDIGGNETVTLRQSFVPVRPGPRQLIASLDSPQLSQVHGVIQVDVAPAPGDGGFFSDAGGDSHLGETIPMASRGGA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AVQ9-1", "uniprot_id": "A0A8M3AVQ9_DANRE", "id": "A0A8M3AVQ9-1", "name": "Protein-glutamine gamma-glutamyltransferase K", "aln": "MPFSCSPYNNNLCGRFTPIKLMADDCRRGACYSPYANSWYNPCASSCGKINRCATPCADPCGYPYGYSYGYPYGSNCGYNYGYPYGYNCGYNYGYPYANRCVNPCTTTTPYVKSCVNPCLDTCVNPCVNPCATPCSTYSYRDYESRQVVTRECIDDCTTKRVCATDEALLRVSKVDLLSCR-TGPNRMEHRTHFFHEEKLIVRRGQCFNMWIDLCRPFNPTCDKLHLELRLGHIPSIRDGTYVIVPIVDEFKKD------CWGARIVERCQNRLKLCVNSLPTSCVGRYQLSVVTHCSAGRFCLPYVPENDIYMLFNPWCKEDCVYLHEETERAEYVLNDIGKIYYGTKHQIGCKSWNFGQFEEGILPACFYVLEKSC-APCSGWGNPINISRVVSDMVIAKKDCGVLMGNWSNCYTDGIAPTSWCGSSAILRQYYKCGGAPVRYGQSLAFAGVTNTMLRCLGIPTRPVSNFCSAHDTDMCLTSDVYLDEKFQLIDHMNANPIWNYHVWNEAWMTRPDLPT----GFGGWQAIDSTPQLTHQGFFRCGPTSVAAIRSGQTFLKHDVPFLFAEVNNDKVYWQRKCDG-TFGVVHVEKDVVGHCISTKAVGSDQRLDITNLYKHPCGSEDRCTALETALRHGCRRI-NYPLP-CAEDVVCEVNLKGDGPCVGRDAVVCINLRNKC-NQPRSVTLYSHAAAMYYTGVRRTYLKRDQTCIELKPSECKPLEWTLSYDEYKEHLVDHAPLMLNLFGHVAQTKQILATQYNFRLRTPDLVLAPACDAVVG-QEVAVKVTFQNPLSCVLRNAAFRFVGLGLQHPRIINYGDIAGHATVSLTEKFIPMCHGPQKLLASFDCPQLTQVHGFTNMVVKQH----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLU2-1", "uniprot_id": "Q9VLU2_DROME", "id": "Q9VLU2-1", "name": "protein-glutamine gamma-glutamyltransferase", "aln": "--------------------------------------------------MGQKLSCCQKCG---------------------------DWKWCTSKDNEESTLRIRNAN------------------ANYFTGIPQGDKTDGASS---------------------AVLGVLKVDLCLEDNHEEHHTSHFYAAAAKEALVVRRGEPFRLKIHFNRDYSPSKDAISFIFTVADDTKPSPGHGTLNALVPHDGIDYLGDTLEWGAGIESHEGQTLTVLIKPPSTCPVTEWKLDIDTKLLG-DGSRSYPLPLPIYVLFNPWCPDDQVYLEDRDQRKEYVMHDTTLIWRGSYNRLRPSVWKIGQFERHVLECSLKVLGTVGRIPPAYRGDPVRVARALSALVNSVDDDGVLLGNWSEDFSGGVAPTKWTGSVEILQQFYKTQ-KSVKFAQCWNFSGVLTTIARSLGIPSRIITCYSSAHDTQASLTVDVFIDANNKKLDAETTDSIWNYHVWNELWMQRPDLGVGEHGTFDGWQVVDATPQEASDNMYRVGPASVAAVKNGDILRPFDGGFVFAEVNADKLYWRYNGPSQPLKLLRKDTLAIGHLISTKAVLKWEREDITDTYKHAERSEEERSTMLKALKQSRHAFSRYYLNDNFNDIEFDMELKDD-IKIGQSFSVVLKVSNKSESRTHMATGQISCDAVLYTGVGAVEVKTLGFELELEPKSSDYVRMEVIFEEYYDKLSSQAAFQISAAAKVKDTDYDYYAQDDFRVRKPDIKFQLGEAAIVAQKELDVILRLENPLPIPLHKGVFTVEGPGIEQPLKFKIAEIPVGGTAAATFKYTPPYAGRGTMLAKFTSKELDDVDGYRHYEIEPRPEDLLQPNGSHRSSNIIRRRTDVIA---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ** . .: . * .:* * *** :: .* : *::***: *.: : : * :. : * : : : :. .. * .: . * . . * * : . : *.: ::. ... : .::: : *: . .: **:****** :* **:... * ***::: *: *: :: *: ***:. :* ..: :* * . *:*: ::*.:* :* : .* ***:***: :: * *: * ** ** .: : .* :.*. *:** .*: *.**:.:* :: : *****: .** *:::* : : :: . :.:**:****: ** **** *.***.:*:*** : ..:: ** ** :::.* .* *:***** **:**: : . .: :: : .:* * ***: . * *** ***. *: . :: .* :. : * :*: ::: :. :*:. * : : *: . : .. . **** .* : * * .. : : :.** :* .:..: :. .:* :: * **:*.**: : *:*. :* * : ::***. * : .* . * *:::* :: .:* *.: .: * * ::*.: . :* :*.* : : ", "identical_positions": 176, "similar_positions": 232, "identity": "19.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-38", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O62609-1", "uniprot_id": "SMAD4_DROME", "id": "O62609-1", "name": "SMAD family member 4", "aln": "MGGGSGACPPAHMYGAVAPQDIIVRDMVQMPPPPSNAPTSADACLSIVHSLMCHRQGGESEGFAKRAIESLVKKLKEKRDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARIWRWPDLHKNELKHVKYCAFAFDLKCDSVCVNPYHYERVVSPGIDLSGLSLQSGPSRLVKDEYSAGPLVGSMDIDGNDIGTIQHHPTQMVGPGGYGYPQGPSEYVGDANPMSAMFPTGRTIPKIEPQDGVAGSRGSWMVPPPPRLGQPPQQQQQQPQQQTPQPTQQQQAQSQAAAHSLPVPHGMPGMPGPMNPGPVMAPPPPPQQAQNPQGNGVHHTQANSPTDPASALAMQQQQQQQQQQQQQQQQQQQQSGGVPNGSVNAGGGAAAGGQYYGQPPPVSQMQGAGGGGTSVAPSVHAQQNGYVSQPGSAGSAPVGGGGVFGTAQPTPQQPQQPPTGVQANTGSAGAQAGAGGGAAGTWTGPNTLTYTQSMQPPDPRSLPGGFWNSSLSGDLGSPQQTPPQQQQQQQQPRLLSRQPPPEYWCSIAYFELDTQVGETFKVPSAKPNVIIDGYVDPSGGNRFCLGALSNVHRTEQSERARLHIGKGVQLDLRGEGDVWLRCLSDNSVFVQSYYLDREAGRTPGDAVHKIYPAACIKVFDLRQCHQQMHSLATNAQAAAAAQAAAVAG-VANQQMGGGGR---SMTAAAGIGVDDLRRLCILRLSFVKGWGPDYPRQSIKETPCWIEVHLHRALQLLDEVLHAMPIDGPRAAA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M3AK78-1", "uniprot_id": "A0A8M3AK78_DANRE", "id": "A0A8M3AK78-1", "name": "Mothers against decapentaplegic homolog", "aln": "--------------------------------MSVNPPNSNDACLSIVHSLMCHRQGGENEGFAKRAIESLVKKLKEKKDELDSLITAITTNGVHPSKCVTIQRTLDGRLQVAGRKGFPHVIYARLWRWPDLHKNELKHVKFCQYAFDLKYDNVCVNPYHYERVVSPG--IVGLSLQN-----TETHLSSGRCLG---------------------------------------------PTGRLIKEEYSHDCIQMD-----VPP----GLPPQQDHQGAMKLPPP-----------DHYGQPLPPLQLPSEGPR------APPPVTLYSNMP----------LSPTASGSMMPMQGGHGEGLLQIASPQGQVMTP----------------------TPPPSTPTHGP---------------------------------------PQTPVPPQPPPN---QNGYNSSKHSQTQGSFHTTWTGSSTASYTPVGPQQNGRGHQPPLHHPHFWSQHHSSASFPPP----------VSNHPGPEFWCSISYFEMDVQVGEMFKVLSSCPVVTIDGYVDPSGGDRFCLGQLSNVHRTDASERARLHIGKGVQLECRGEGDVWMRCMSDHAVFVQSYYLDREAGRAPGDAVHKIYPGAYIKVFDLRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAVSLSAAAGIGVDDLRRLCILRLSFVKGWGPDYPRQSIKHTPCWVEVHLHRALQLLDEVLHTMPLADPGPAN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *.*.* ******************.******************:**************.*******************************:***************:* :***** *.*************** : *****. .: . *:* :* **** * : .:* : . *** * ****::* . : .* :. *:* ** **** . :: * *** ..* :.** : : * . * * . *** : :*. ** ** **. * .:. :: : *. ****..* :** : *. : :. : .: *. . ** :*.:* **:****:***:*.**** *** *: * * **********:***** *******: **************: *******:**:**::**************:**********.* **********:**:. *:.************** :.. ** *::**********************************.****:****************:**: .* .* ", "identical_positions": 368, "similar_positions": 98, "identity": "47.48%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-39", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29973-1", "uniprot_id": "CNGA1_HUMAN", "id": "P29973-1", "name": "Cyclic nucleotide-gated channel alpha-1", "aln": "MKNNIINTQQSFVTMPNVIVPDIEKEIRRMENGACSSFSEDDDSASTSEESENENPHARGSFSYKSLRKGGPSQREQYLPGAIALFNVNNSSNKDQEPEEKKKKKKEKKSKSDDKNENKNDPEKKKKK-KDKEKKKKEEKSKDKKEEEKKEVVVIDPSGNTYYNWLFCITLPVMYNWTMVIARACFDELQSDYLEYWLILDYVSDIVYLIDMFVRTRTGYLEQGLLVKEELKLINKYKSNLQFKLDVLSLIPTDLLYFKLGWNYPEIRLNRLLRFSRMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVFYSISKAIGFGNDTWVYPDINDPEFGRLARKYVYSLYWSTLTLTTIGETPPPVRDSEYVFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEFQARIDAIKQYMHFRNVSKDMEKRVIKWFDYLWTNKKTVDEKEVLKYLPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGVTQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAKTMLEEKGKQILMKDGLLDLNIANAGSDPKDLEEKVTRMEGSVDLLQTRFARILAEYESMQQKLKQRLTKVEKFLKPLIDTEFSSIEGPGAESGPIDST--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P29974-1", "uniprot_id": "CNGA1_MOUSE", "id": "P29974-1", "name": "Cyclic nucleotide-gated channel alpha-1", "aln": "MKTNIINTWHSFVNIPNVIVPAIEKEIRRMENGACSSFS-DDDNGSLSEESENEDSFFR-SNSYK---RRGPSQREQHLPGTMALFNVNNSSNKDQEPKEKKKKKKEKKSKADDKNENKKDPEKKKKKEKEKEKKKKEEKTKEKKEEEKKEVVVIDPSGNTYYNWLFCITLPVMYNWTMIIARACFDELQSDYLEYWLIFDYVSDVVYLADMFVRTRTGYLEQGLLVKDRMKLIEKYKANLQFKLDVLSVIPTDLLYIKFGWNYPEIRLNRLLRISRMFEFFQRTETRTNYPNIFRISNLVMYIVIIIHWNACVYYSISKAIGFGNDTWVYPDVNDPEFGRLARKYVYSLYWSTLTLTTIGETPPPVLDSEYIFVVVDFLIGVLIFATIVGNIGSMISNMNAARAEFQSRVDAIKQYMNFRNVSKDMEKRVIKWFDYLWTNKKTVDEREVLRYLPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGITQFVVLSDGSYFGEISILNIKGSKAGNRRTANIKSIGYSDLFCLSKDDLMEALTEYPDAKTMLEEKGRQILMKDGLLDINIANMGSDPKDLEEKVTRMEGSVDLLQTRFARILAEYESMQQKLKQRLTKVEKFLKPLIETEFSALEEPGGESELTESLQD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B5U3-1", "uniprot_id": "A0ACD6B5U3_DANRE", "id": "A0ACD6B5U3-1", "name": "", "aln": "MSARVRPLDPPRFLVEGVEQVTMEDVIENKRPDAGALFN----NTNNSNNNEEED------------------------------------KKKKKKEKKEKKEKKEKKEKKEKKEKKKEQEEKEKEKEKEKEKEKEKEKEKEKKEPPK-EIEVVDPAGNMYYNWLFVITCPVMYNWIFIIARACFEELQGDYLILWFFLDYLSDAVYLLDMVFRTRTGYLEQGLLVKDQKKLRDRYTDSLQFRLDLASMVPTDVFYLYFGMNYPEIRMNKLLRINRLFEFFQRTETRTNFPNVFRISNLVMYIVIIIHWNACMYYSFSKAIGFGSDAFVYPDPSDPEFGRLVRKYAYSMYWSTLTLTTIGETPPPVENSEYFFVVTDFLVGVLIFATIVGNVGSMITNANAARADFQARIDAIKQYMSFRKVTKDLEKRVIKWFDYLWTNKKAVDEREVLKYLPDKLRAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGITQFVVLSDGSYFGEISILNIKGSRAGNRRTANIRSIGYSDLFCLSKDDLMEALTEYPDAKAMLEEKGRQILMKDNLLDLELAKQGPDPKDMEEKVQKIGGVLEDLQTRFARLLAEQEAAQGKLKKRVTKLEKKMT-----SETLMEPPPETADKTD----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. .: . . : .* :*. *.. . .* : *. . . *::.*:*: .:*.:: :::**:*****.* :.*:::*:: **:*:* *:***:*::** *:*** * *: *:**:** ****** ** ****** ::******:***.*** *:::**:** *** **..**************:. ** ::*. .***:**: *::***::*: :* ******:*:***:.*:************:**:*******************::**:*******.*::**** .*******.***.**:***************** :***.***.***:***********:****:* *****:**:*:******* **:*:**:****************:***:***:****************************************************************************:***********************:*********:**************************:******:******.***:::*: *.****:**** :: * :: *******:*** *: * ***:*:**:** :. . : :* * : : ", "identical_positions": 442, "similar_positions": 133, "identity": "64.15%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LQW0-1", "uniprot_id": "F1LQW0_RAT", "id": "F1LQW0-1", "name": "Transporter", "aln": "MLLARMKPQVQPELGGADQLPEQPLRP-CKTADLLVVKEHNGVQCL------------LASQDGDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQFNREGAATVW-KICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLNLPWTNCGHAWNSPNCTDPKLLNAS---VLGDHTKYSKYKF---------------------------TPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVIVVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINCVTSFISGFAIFSILGYMAHEHKVKIEDVATEGAGLVFVLYPEAISTLSGSTFWAVLFFLMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCAVTLGTFLLAMFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYVYPPWANWVGWGIALSSMILVPAYVIYKFFSIRGSLWERVAYGITPENEHHLVAQR------DVRQFQLRHWLAI------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55192-1", "uniprot_id": "SC6A2_MOUSE", "id": "O55192-1", "name": "Sodium-dependent noradrenaline transporter", "aln": "MLLARMNPQVQPELGGADPLPEQPLRP-CKTADLLVVKERNGVQCL------------LASQDSDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVW-KICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFASFTLNLPWTNCGHSWNSPNCTDPKLLNAS---VLGDHTKYSKYKF---------------------------TPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVIVVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSTINCVTSFISGFAIFSILGYMAHEHKVNIEDVATEGAGLVFILYPEAISTLSGSTFWAVLFFLMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTCVVTISTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFKPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYTYPPWANWVGWGIALSSMILVPAYVIYKFLSIRGSLWERVAYGITPENEHHLVAQR------DVRQFQLRHWLAI------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23975-1", "uniprot_id": "SC6A2_HUMAN", "id": "P23975-1", "name": "Sodium-dependent noradrenaline transporter", "aln": "MLLARMNPQVQPENNGADTGPEQPLRA-RKTAELLVVKERNGVQCL------------LAPRDGDAQPRETWGKKIDFLLSVVGFAVDLANVWRFPYLCYKNGGGAFLIPYTLFLIIAGMPLFYMELALGQYNREGAATVW-KICPFFKGVGYAVILIALYVGFYYNVIIAWSLYYLFSSFTLNLPWTDCGHTWNSPNCTDPKLLNGS---VLGNHTKYSKYKF---------------------------TPAAEFYERGVLHLHESSGIHDIGLPQWQLLLCLMVVVIVLYFSLWKGVKTSGKVVWITATLPYFVLFVLLVHGVTLPGASNGINAYLHIDFYRLKEATVWIDAATQIFFSLGAGFGVLIAFASYNKFDNNCYRDALLTSSINCITSFVSGFAIFSILGYMAHEHKVNIEDVATEGAGLVFILYPEAISTLSGSTFWAVVFFVMLLALGLDSSMGGMEAVITGLADDFQVLKRHRKLFTFGVTFSTFLLALFCITKGGIYVLTLLDTFAAGTSILFAVLMEAIGVSWFYGVDRFSNDIQQMMGFRPGLYWRLCWKFVSPAFLLFVVVVSIINFKPLTYDDYIFPPWANWVGWGIALSSMVLVPIYVIYKFLSTQGSLWERLAYGITPENEHHLVAQR------DIRQFQLQHWLAI------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R3H6-1", "uniprot_id": "F1R3H6_DANRE", "id": "F1R3H6-1", "name": "Transporter", "aln": "-----MNIQVLPEHKLSSVAPLKQFNVEKKEVELILVKEQNGVQYTNSSVVASPSSRACTSASGEEIERETWGKKMDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLIPYVLFLFIAGMPLFYMELALGQYNREGAATLW-KICPVFKGVGYTVIVIALYVGFYYNVIIAWSLYYLYASLTSELPWLHCNNPWNSPNCTEPKDINGT---VLGNGTSYAKYKN---------------------------TPAAEFYERGVLHSHESKGIGDLGLPRWELTICLVVVAFILYFSLWKGVKSSGKVVYITATMPYIVLLVLLIRGITLPGAMNGIRAYLHIDLKKLNNPQVWIDAATQIFFSLGAGFGVLIAFSSYNKFNNNCYRDAILTSTINCVTSFFSGFAIFSVLGYMAEQHKVNIKDVATEGAGLVFVIYPEAISTLPGATFFAIVFFIMLLTLGIDSSMGGMEAVLTGLSDDFKILKRNRKLFTFATVVGTFLMALLCVTNGGIYVLTLLDKYAAGTSILFGVLFEAIGVSWFYGVDRFSEDIERMMGFKPGIYWRLCWKFVSPAFLLLVVIASIVTSGRLTYDEYVFPYWADMLGWSIALSSMLFVPFYAIYKFFSVPSSFKERLAYCVTPEHEHHLVAEG------NVRQFKLKHWLTI------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7K4Y6-1", "uniprot_id": "DAT_DROME", "id": "Q7K4Y6-1", "name": "Sodium-dependent dopamine transporter", "aln": "---------MSPTGHISKSKTPTPHDN-----------DNNSISDE----------------------RETWSGKVDFLLSVIGFAVDLANVWRFPYLCYKNGGGAFLVPYGIMLVVGGIPLFYMELALGQHNRKGAITCWGRLVPLFKGIGYAVVLIAFYVDFYYNVIIAWSLRFFFASFTNSLPWTSCNNIWNTPNCRPFESQNASRVPVIGNYSDLYAMGNQSLLYNETYMNGSSLDTSAVGHVEGFQSAASEYFNRYILELNRSEGIHDLGAIKWDMALCLLIVYLICYFSLWKGISTSGKVVWFTALFPYAVLLILLIRGLTLPGSFLGIQYYLTPNFSAIYKAEVWVDAATQVFFSLGPGFGVLLAYASYNKYHNNVYKDALLTSFINSATSFIAGFVIFSVLGYMAHTLGVRIEDVATEGPGLVFVVYPAAIATMPASTFWALIFFMMLLTLGLDSSFGGSEAIITALSDEFPKIKRNRELFVAGLFSLYFVVGLASCTQGGFYFFHLLDRYAAGYSILVAVFFEAIAVSWIYGTNRFSEDIRDMIGFPPGRYWQVCWRFVAPIFLLFITVYGLIGYEPLTYADYVYPSWANALGWCIAGSSVVMIPAVAIFKLLSTPGSLRQRFTILTTPWRDQQSMAMVLNGVTTEVTVVRLTDTETAKEPVDV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :. . :.*.:. ****. *:******:*************************:** ::*.:.*:***********.**:** * * :: *.***:**:*::**:**.*********** ::::*:* .*** *.: **:*** : *.: *:*: :. :.*:*:::* :*. :.*.** *:* :*:: :**::* .: *******:.:*****::** :** **::**::*:****: **. ** :: : :. **:*****:*****.*****:*::****:.** *:**:*** **. ***.:**.***:*****. *.*:******.****::** **:*:..:**:*::**:***:**:***:** **::*.*:*:* :**:*:**. *::.: . *:**:*.: *** :*** ***..*::***.***:**.:***:**. *:** ** **::**:**:* ***::.: .:: *** :* :* **: :** ** **::::* .*:*::* .*: :*.: ** .::: :* :: .:* . : ", "identical_positions": 291, "similar_positions": 186, "identity": "43.24%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-40", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q924Z4-1", "uniprot_id": "CERS2_MOUSE", "id": "Q924Z4-1", "name": "Ceramide synthase 2", "aln": "---MLQTLYDYFWWERLWLPVNLTWADLE----------------------DKDGRVYAKAS---DLYITLPLALLFLVIR--YFFELYVATPLAALLNVKEKTRLRAPPNATLEHFYQTSGKQPKQV----------EVDLLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFTYYLIAFVAGMAVTVD-KPWFYDLRKVWEGYPIQSIIPSQYWYYMIELSFYWSLLFSIASDVK--RKDFKEQIIHHVATIILLCFSWFANYVRAGTLIMALHDASDYLLESAKMFNYAG--WKNTCNNLFIVFAIVFIITRLVIMPFWILHCT-------MIYPLELYPAFFGYYFFNFMMAVLQMLHIFWAYFILRMAHKFITG-KLIEDERS-DREETESSEGEETAAGAGAKSR--LLANG--------------HPILNNNHPKND", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "G3V8V4-1", "uniprot_id": "G3V8V4_RAT", "id": "G3V8V4-1", "name": "", "aln": "---MLQTLYDYFWWERLWLPVNLTWADLE----------------------DKDGRVYAKAS---DLYITLPLALLFLIIR--YFFELYVATPLAALLNVKEKTRLRAPPNATLEHFYLTVGKQPKQV----------EVDLLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFTYYLIAFVAGMAVTVD-KPWFYDLRKVWEGYPIQSIIPSQYWYYMIELAFYWSLLFSIASDVK--RKDFKEQIIHHVATIILLCFSWFANYVRAGTLIMALHDSSDYLLESAKMFNYAG--WKNTCNNLFIVFAVVFIITRLVIMPFWILHCT-------MIYPLEFYPAFFGYYFFNSMMVVLQMLHVFWAYFIVRMAHKFITG-KLVEDERS-DREETESSEGEEAAAGAGAKSR--LLANG--------------HPILNNNHPKND", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96G23-1", "uniprot_id": "CERS2_HUMAN", "id": "Q96G23-1", "name": "Ceramide synthase 2", "aln": "---MLQTLYDYFWWERLWLPVNLTWADLE----------------------DRDGRVYAKAS---DLYITLPLALLFLIVR--YFFELYVATPLAALLNIKEKTRLRAPPNATLEHFYLTSGKQPKQV----------EVELLSRQSGLSGRQVERWFRRRRNQDRPSLLKKFREASWRFTFYLIAFIAGMAVIVD-KPWFYDMKKVWEGYPIQSTIPSQYWYYMIELSFYWSLLFSIASDVK--RKDFKEQIIHHVATIILISFSWFANYIRAGTLIMALHDSSDYLLESAKMFNYAG--WKNTCNNIFIVFAIVFIITRLVILPFWILHCT-------LVYPLELYPAFFGYYFFNSMMGVLQLLHIFWAYLILRMAHKFITG-KLVEDERS-DREETESSEGEEAAAGGGAKSR--PLANG--------------HPILNNNHRKND", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9X7-1", "uniprot_id": "E7F9X7_DANRE", "id": "E7F9X7-1", "name": "", "aln": "---MLAGLSELFWQERLWFPEGLGWADLE----------------------DRDGRVYAKAR---DLWVALPIAVLFLLIR--QLFEKYVATPLASLLGLKETVRRRVAHNPALESYYCNTSKNPTQS----------SVEKLSKQTGWTERQVQRWFRRRRNQDRPNLLKKFCEASWRFAFYLLAFIGGLAALID-KPWLYDLEEMWKGFPTLTLLPSQYWYYMLELAFYTSLLFSVASDVK--RKDFKEQIIHHVATILLISFSWCVNYIRAGTLIMFMHDSADYLLESAKMFNYAR--WKNACNYIFILFAAIFIVTRLIIFPFRIMYCT-------WVYPVTLYPPFFGYYFFNGLLMVLLCLHMFWAALIIRLAFRFLSSNSSVEDERS-DRDETDESEEEEELKNGEIKKKNGAAQNG--------------HATYNNNHSKTE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W423-1", "uniprot_id": "Q9W423_DROME", "id": "Q9W423-1", "name": "", "aln": "-MDILNEFSNVFWSTHIWLPPNTTWADIAP--------------------GSRPDVVHANYK---DLIWPIPFAAVVMLVR--YTLERFWISPVGKSLGIRSSRPKKAANVPILEKTYAKSTRLDKKK----------LVP-LSKQTDMSEREIERWWRLRRAQDKPSTLVKFCENTWRCIYYLYSFIFGVIVLWD-KPWFWDVKSCWYGYPHQSISNDIWWYYMISMSFYWSLTGTQFFDVK--RKDFWQMFIHHMVTLLLMSLSWVCNLHRVGSLVLVVHDCADIFLEAAKLTKYAK--YQKLCDAIFAIFTVVWIVTRLGFYP-RIIYSS-------SVEAPRILPMFPAYYIFNSLLLMLLVLHVIWTYMILKIVVDSLQKGLMSGDIRSSDSEDLTDSSGNARLTNGSARSKNKSISSAPSDKGSAGGAGSRAGARVATTERREE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38703-1", "uniprot_id": "LAG1_YEAST", "id": "P38703-1", "name": "Ceramide synthase LAG1", "aln": "MTSATDKSIDRLVVNAKTRRRNSSVGKIDLGDTVPGFAAMPESAASKNEAKKRMKALTGDSKKDSDLLWKVWFSYREMNYRHSWLTPFFILVCVYSAYFLSGNRTESNPLHMFVAISYQVDGTDSYAKGIKDLSFVFFYMIFFTFLREFLMDVVIRPFTVYLNVTSEHRQKRMLEQMYAIFYCGVSGPFGLYIMYHSDLWLFKTKPMYRTYPVITNPFLFKIFYLGQAAFWAQQACVLVLQLEKPRKDYKELVFHHIVTLLLIWSSYVFHFTKMGLAIYITMDVSDFFLSLSKTLNYLNSVFTPFVFGLFVFFWIYLRHVVNIRILWSVLTEFRHEGNYVLNFATQQYKCWISLPIVFVLIAALQLVNLYWLFLILRILYRLIWQGIQKDERSDSDSDESAENEESKEKCE---------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . ..: .: : .. ** : :: : * : : : . . : * : :: : * : :: * : : : *: . . *::. . : :* : :*: . :*: . ::: ***: : .:**:.*::*: *: : : * : * :* :*. :* :* : :* .* . :: . : . :. :: * ::: * :*::: : : . * :: ... . ", "identical_positions": 31, "similar_positions": 97, "identity": "6.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-46", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6NS86-1", "uniprot_id": "ZN366_MOUSE", "id": "Q6NS86-1", "name": "Zinc finger protein 366", "aln": "MQKAMKMVKDEDGPLNAAAKSIPSFPHCLQPEASRGKAPQRHPFPEALRGPFSQFRYEPSPGDLDGFPEVFEGGGSRKRKSMPTKVPYTHPAEEASIAQES---KSLGPPNLTLLFPQPQRPKCDSQMIDLCNVGLQFYRTLEHLG-GKPVKQEPVKPSAMWPQPTPPAFLPAPYPYYPKVHPGLM-FPFFVPSSSPFPFSRHTFLPKQPPEPVLPRKVEPLESEETKQKVERVDVNVQIDDSYYVDVGGAQKRWQCPTCEKSYTSKYNLVTHILGHSGIKPHACSRCGKLFKQLSHLHTHMLTHQGTRPHKCQVCHKAFTQTSHLKRHMMQHSEVKPHNCRVCSRGFAYPSELKAHEAKHASGRENICVECGLDFPTLAQLKRHLTTHRGPIQYNCSECDKTFQYPSQLQNHMMKHKDIRPYICSECGMEFVQPHHLKQHSLTHKGVKEHKCGICGREFTLLANMKRHVLIHTNIRAYQCHLCYKSFVQKQTLKAHMIVHSDVKPFKCKLCGKEFNRMHNLMGHLHLHSDSKPFKCLYCPSKFTLKGNLTRHMKVKHGVMERGLHSQGLGR-GRLVLVQSAGVLRNLEQEEPFDLSQKRSANGPMFQSDVDSTQDCLCQEEEEEAGEEDNCYEVEPYSPSLAPESQQLCAPEDLSTKQEQTLQDPGEGCRDQDAPEEQQEDRSEDHEGSDIDCEG-KDIDCAIREERLSSRLLQSGGQGPSFSDYLYFKHRDEGLKELLERKMEKQAVLLGI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N895-1", "uniprot_id": "ZN366_HUMAN", "id": "Q8N895-1", "name": "Zinc finger protein 366", "aln": "MQKEMKMIKDEDVHFDLAVKKTPSFPHCLQPVASRGKAPQRHPFPEALRGPFSQFRYEPPPGDLDGFPGVFEGAGSRKRKSMPTKMPYNHPAEEVTLALHSEENKNHGLPNLPLLFPQPPRPKYDSQMIDLCNVGFQFYRSLEHFG-GKPVKQEPIKPSAVWPQPTPTPFLPTPYPYYPKVHPGLM-FPFFVPSSSPFPFSRHTFLPKQPPEPLLPRKAEPQESEETKQKVERVDVNVQIDDSYYVDVGGSQKRWQCPTCEKSYTSKYNLVTHILGHSGIKPHACTHCGKLFKQLSHLHTHMLTHQGTRPHKCQVCHKAFTQTSHLKRHMMQHSEVKPHNCRVCGRGFAYPSELKAHEAKHASGRENICVECGLDFPTLAQLKRHLTTHRGPIQYNCSECDKTFQYPSQLQNHMMKHKDIRPYICSECGMEFVQPHHLKQHSLTHKGVKEHKCGICGREFTLLANMKRHVLIHTNIRAYQCHLCYKSFVQKQTLKAHMIVHSDVKPFKCKLCGKEFNRMHNLMGHMHLHSDSKPFKCLYCPSKFTLKGNLTRHMKVKHGVMERGLHSQGLGR-GRIALAQTAGVLRSLEQEEPFDLSQKRRAKVPVFQSDGESAQGSHCHEEEE----EDNCYEVEPYSPGLAPQSQQLCTPEDLSTKSEHAPEVLEEACKEE--KEDASKGEWEKRSKGDLGAEGGQERDCAGRDECLSLRAFQSTRRGPSFSDYLYFKHRDESLKELLERKMEKQAVLLGI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B770-1", "uniprot_id": "A0ACD6B770_DANRE", "id": "A0ACD6B770-1", "name": "Zinc finger protein 710", "aln": "----------------------------------------------------------------------MDSSESKRSEDASSRS--------VDLALLP--------PHHP-VFPHPHR--FTPEMIDLS--RLRLHRVLHTVKNGRDFNVQVKQELPLWPP--SPLLLRSPAPYFPPFHPSLVPFPFLLPGSVPN-LSPNPFYP---SEPFHVHRRPPDGPE---------KLNVHVDDSYYVDVGGDQKRWKCRMCEKSYTSKYNLITHILGHSGIKPHACSLCGKLFKQLSHLHTHMLTHQGTRPHKCQVCHKAFTQTSHLKRHMMQHSDVKPYSCSVCGRGFAYPSELRAHELKHERGQENVCVECGLDFPTLAQLKRHLTAHRGPVQYACSECGKSFQYPSQLQNHMMKHKDIRPFICSECGMEFVQSHHLKQHTLTHKGVKEHKCRICGREFTLLANMKRHVLIHTNIRAYQCELCYKSFVQKQTLKAHMIVHSDIKPYKCKLCGKEFNRMHNLMGHMHLHSDSKPFKCLYCASKFTLKGNLTRHMKIKHGIMDQGLDARVCRRRGRLCLSGPLRILSRIGQDEPFDLSQKNPLR--LSQSDGESVRGGSSSREED----EDSVYRMSQYSP---------------------DRENPAEARDQE--------------------------------DEKKTSHLAQIHS------------DKEEDF-----------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.. *:: :. .:: . :* . *: . :**:* * .:****. ::::* *. . *: .: : : .:** .. :* :* **:* .**.*: ***::*.* * :* :.* * .**. :: * .* .:**::********** ****:* ***********:**************: ***********************************************:***:.* **.*********:*** ** *:**:*******************:****:** ****.*:*******************:***********.******:*********** ***************************.*********************:**:******************:**************.**************:***:*::**.:: * **: * . :* : *:********. . : *** :*.:. . .**: **. *.:. *** : *. :: :* : : * .::*.: ", "identical_positions": 358, "similar_positions": 117, "identity": "47.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AQ07-1", "uniprot_id": "TBB1_MOUSE", "id": "A2AQ07-1", "name": "Tubulin beta-1 chain", "aln": "MREIVHIQIGQCGNQIGAKFWEVIGEEHGIDCAGSYCGTSALQLERISVYYNEAYGKKYVPRAVLVDLEPGTMDSIRSSRLGVLFQPDSFVHGNSGAGNNWAKGHYTEGAELIENVMDVVRRESESCDCLQGFQIVHSLGGGTGSGMGTLLMNKIREEYPDRILNSFSVMPSPKVSDTVVEPYNAVLSIHQLIENTDACFCIDNEALYDICFRTLRLTTPTYGDLNHLVSLTMSGITTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTAQGSQQYRALSVAELTQQMFDARNIMAACDPRRGRYLTVACIFRGKMSTKEVDQQLLSIQTRNSNCFVEWIPNNVKVAVCDIPPRGLNMAATFLGNNTAIQELFTRVSEHFSAMFRRRAFVHWYTSEGMDISEFGEAESDIHDLVSEYQQFQDVRAGLEDSEEDVEEAEVEAEDKDH---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4B7-1", "uniprot_id": "TBB1_HUMAN", "id": "Q9H4B7-1", "name": "Tubulin beta-1 chain", "aln": "MREIVHIQIGQCGNQIGAKFWEMIGEEHGIDLAGSDRGASALQLERISVYYNEAYGRKYVPRAVLVDLEPGTMDSIRSSKLGALFQPDSFVHGNSGAGNNWAKGHYTEGAELIENVLEVVRHESESCDCLQGFQIVHSLGGGTGSGMGTLLMNKIREEYPDRIMNSFSVMPSPKVSDTVVEPYNAVLSIHQLIENADACFCIDNEALYDICFRTLKLTTPTYGDLNHLVSLTMSGITTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTAQGSQQYRALSVAELTQQMFDARNTMAACDLRRGRYLTVACIFRGKMSTKEVDQQLLSVQTRNSSCFVEWIPNNVKVAVCDIPPRGLSMAATFIGNNTAIQEIFNRVSEHFSAMFKRKAFVHWYTSEGMDINEFGEAENNIHDLVSEYQQFQDAKAVLEEDEEVTEEAEMEPEDKGH---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FC32-1", "uniprot_id": "E7FC32_DANRE", "id": "E7FC32-1", "name": "Tubulin beta chain", "aln": "MREIVHLQIGQCGNQIGSKFWEVISDEHGINRVGAYEGDMDLQLERVNVYFNEAHGGKYVPRALLVDLEPGTMDSVRGSQIGQLFRPDNFIHGNSGAGNNWAKGHYTEGAELVEQVVDRVRNEAESCDCMQGFQFVHSLGGGTGSGMGTLIINKIREEYPDRIMNSFSVMPSPKVSDTVVEPYNATLSIHQLIENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSLTMSGVTTSLRFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTARGSQQYRALTVPELTQQMFDPRNMMTACDPRRGRYLTVAGIFRGRMSTKEVDEQMLAIQQKNSNYFVDWIPHNVKVAVCDIPPRGLKMASTFIGNNTAIQEVFKRIGEQFALMFRRKAFLHWYTGEGMDELEFSEAESNLNDLVSEYQQYQDATADMDYEEEEVMEEESSIAHSTQVEIKTEVVTETSVSE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:**********:****:*.:****: .*: * *****:.**:***:* ******:***********:*.*::* **:**.*:*********************:*:*:: **.*:*****:****:***************::***********:*********************.*********:* :***************:*******************:***************************************:********:*.********.** *:*** ********* ****:*******:*:*::* :**. **:***:**************.**:**:********:*.*:.*:*: **:*:**:****.**** **.***.:::********:**. * :: .** . * * . .. : ", "identical_positions": 344, "similar_positions": 78, "identity": "73.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-50", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5SZQ8-1", "uniprot_id": "CELF3_HUMAN", "id": "Q5SZQ8-1", "name": "CUGBP Elav-like family member 3", "aln": "MKEPDAIKLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLGKQQTDEDVRKMFEPFGTIDECTVLRGPDGTSKGCAFVKFQTHAEAQAAINTLHSSRTLPGASSSLVVKFADTEKERGLRRMQQVATQLGMFSPIALQFGAYSAYTQALMQQQAALVAAHSAYLSPMATMAAVQMQHMAAINANGLIATPITPSSGTSTPPAIAATPVSAIPAALGVNGYSPVPTQPTGQPAPDALYPNGVHPYPAQSPAAPVDPLQQAYAGMQHYTAAYPAAYSLVAPAFPQPPALVAQQPPPPPQQQQQQQQQQQQQQQ-REGPDGCNIFIYHLPQEFTDSEILQMFVPFGHVISAKVFVDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CIN6-1", "uniprot_id": "CELF3_MOUSE", "id": "Q8CIN6-1", "name": "CUGBP Elav-like family member 3", "aln": "MKEPDAIKLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTYCARDSALKAQSALHEQKTLPGMNRPIQVKPADSESRG-DRKLFVGMLGKQQTDEDVRKMFEPFGTIDECTVLRGPDGTSKGCAFVKFQTHAEAQAAINTLHSSRTLPGASSSLVVKFADTEKERGLRRMQQVATQLGMFSPIALQFGAYSAYTQALMQQQAALVAAHSAYLSPMATMAAVQMQHMAAISANGLIATPITPSSGTSTPPAIAATPVSAIPAALGVNGYSPVPTQPTGQPAPDALYPNGVHPYPAQSPAAPVDPLQQAYAGMQHYTAAYPAAYSLVAPAFPQPPALVAQQPPPPPQQQQQQQQQQQQQQQQREGPDGCNIFIYHLPQEFTDSEILQMFVPFGHVISAKVFVDRATNQSKCFGFVSFDNPASAQAAIQAMNGFQIGMKRLKVQLKRPKDANRPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F293-1", "uniprot_id": "E7F293_DANRE", "id": "E7F293-1", "name": "", "aln": "MKEPDAIKLFIGQIPRNLEEKDLKPIFEQYGKIYELTVIKDKYTGMHKGCAFLTYCARESAVKAQSALHEQKTLPGMNRPIQVKPADSEGRGEDRKLFVGMLGKQQSDEDVRKIFEPFGGIDECTVLRGPDGTSKGCAFVKFQSHSEAQSAINSLHGSRTLPGASSSLVVKFADTEKERGVRRMQQVTSQLGVYTPVTLNFNAYNAYTQALVQQQALVAQAQ--YLSPAASM---QIQQMAALNASGIIATPITPPSGANTPPTLAATPVSALPQPIAVNGYSHLPPTTNGQPAS-EIYTNGLHPYQAQSPVAALDPLQQAYAGMQHYTAAYPTAYGLVSPQFLQQPTLISQQ------------------QLQREGPEGCNVFIYHLPQEFTDSEMLQMFLPFGNVISAKVFVDRATNQSKCFGFVSFDNPASAQTAIQAMNGFQIGMKRLKVQLKRPKDANRPY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********:*****:************:*:*:***********:************:**:***************************.** *************:******:***** ***********************:*:***:***:**.***********************:******::***:::*::*:*.**.******:**** :. *: **** *:* *:*:***:.*.*:*******.**:.***::*******:* .:.***** :*. ..****. :*.**:*** ****.*.:******************:**.**:* * * *:*::** * ****:***:*************:****:***:******************************:*****************************", "identical_positions": 357, "similar_positions": 70, "identity": "76.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-51", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P16446-1", "uniprot_id": "PIPNA_RAT", "id": "P16446-1", "name": "Phosphatidylinositol transfer protein alpha isoform", "aln": "MVLLKEYRVILPVSVDEYQVGQLYSVAEASKNETGGGEGVEVLVNEPYEKDD-----GEKGQYTHKIYHLQSKVPTFVRMLAPEGALNIHEKAWNAYPYCRTVITN-EYMKEDFLIKIETWHKP-DLGTQENVHKLEPEAWKHVEAIYIDIADRSQVLSKDYKAEEDPAKFKSIKTGRGP-LGPNWKQELVNQKDCPYMCAYKLVTVKFKWWGLQNKVENFIHKQEKRLFTNFHRQLFCWLDKWVDLTMDDIRRMEEETKRQLDEMRQKDPVKGMTADD-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P53810-1", "uniprot_id": "PIPNA_MOUSE", "id": "P53810-1", "name": "Phosphatidylinositol transfer protein alpha isoform", "aln": "MVLLKEYRVILPVSVDEYQVGQLYSVAEASKNETGGGEGVEVLVNEPYEKDD-----GEKGQYTHKIYHLQSKVPTFVRMLAPEGALNIHEKAWNAYPYCRTVITN-EYMKEDFLIKIETWHKP-DLGTQENVHKLEPEAWKHVEAIYIDIADRSQVLSKDYKAEEDPAKFKSVKTGRGP-LGPNWKQELVNQKDCPYMCAYKLVTVKFKWWGLQNKVENFIHKQEKRLFTNFHRQLFCWLDKWVDLTMDDIRRMEEETKRQLDEMRQKDPVKGMTADD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00169-1", "uniprot_id": "PIPNA_HUMAN", "id": "Q00169-1", "name": "Phosphatidylinositol transfer protein alpha isoform", "aln": "MVLLKEYRVILPVSVDEYQVGQLYSVAEASKNETGGGEGVEVLVNEPYEKD------GEKGQYTHKIYHLQSKVPTFVRMLAPEGALNIHEKAWNAYPYCRTVITN-EYMKEDFLIKIETWHKP-DLGTQENVHKLEPEAWKHVEAVYIDIADRSQVLSKDYKAEEDPAKFKSIKTGRGP-LGPNWKQELVNQKDCPYMCAYKLVTVKFKWWGLQNKVENFIHKQERRLFTNFHRQLFCWLDKWVDLTMDDIRRMEEETKRQLDEMRQKDPVKGMTADD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RHH5-1", "uniprot_id": "A0A8M1RHH5_DANRE", "id": "A0A8M1RHH5-1", "name": "Phosphatidylinositol transfer protein alpha isoform", "aln": "-MLIKEFRVILPISVEEYQVGQLYSVAEASKNETGGGEGVEVLKNEPYEKD------GEKGQYTHKIYHLQSKVPSFVRMLAPASALNIHEKAWNAYPYCRTVITN-EYMKENFLIKIETWHKP-DMGQQDNVHGLDPDTWKKVDVVYIDIADRSQVEPKDYKPEEDPSKYKSVKTGRGP-LGPDWKRELPKKTDCPHMCAYKLVTVKFKWWGLQNKVENFIQKQEKRLFTNFHRQLFCWIDKWIELNMDDIRRMEEETRKELDEMRVKDPVKGMVALED", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KGG5-1", "uniprot_id": "A0A0B4KGG5_DROME", "id": "A0A0B4KGG5-1", "name": "", "aln": "-MQIKEFRVTLPLTVEEYQVAQLFSVAEASKENTGGGEGIEVLKNEPFEDFPLLGGKYNSGQYTYKIYHLQSKVPAYIRLLAPKGSLEIHEEAWNAYPYCRTIITNPGYMDKNFKIDIYSQHIENDLGTVDNVHELTPDKLKVREIVHIDIAN-DPVLPADYKPDEDPTTYQSKKTGRGPLVGSDWKKHVN-----PVMTCYKLVTCEFKWFGLQTRVENFIQKSERRLFTNFHRQVFCSTDRWYGLTMEDIRAIEDQTKEELDKARQVGEVRGMRADAD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :**:** **::*:****.**:*******::******:*** ***:*. :.****:**********:::*:*** .:*:***:**********:*** **.::* *.* : * *:* :*** * *: * : ::****: . * . ***.:***:.::* ****** :*.:**:.: * * .***** :***:***.:*****:*.*:*********:** *:* *.*:*** :*::*:.:**: * . *:** * ", "identical_positions": 150, "similar_positions": 72, "identity": "53.57%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-55", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O94991-1", "uniprot_id": "SLIK5_HUMAN", "id": "O94991-1", "name": "SLIT and NTRK-like protein 5", "aln": "MHTCCPPVTLEQDLHRKMHSWMLQTLAFAVTSLVLSCAETIDYYGEICDNACPCEEKDGILTVSCENRGIISLSEISPPRFPIYHLLLSGNLLNRLYPNEFVNYTGASILHLGSNVIQDIETGAFHGLRGLRRLHLNNNKLELLRDDTFLGLENLEYLQVDYNYISVIEPNAFGKLHLLQVLILNDNLLSSLPNNLFRFVPLTHLDLRGNRLKLLPYVGLLQHMDKVVELQLEENPWNCSCELISLKDWLDSISYSALVGDVVCETPFRLHGRDLDEVSKQELCPRRLISDYEMRPQTPLSTTGYLHTTPASVNSVATSSSAVYKPPLKPPKGTRQPNKPRVRPTSRQPSKDLGYSNYGPSIAYQTKSPVPLECPTACSCNLQISDLGLNVNCQERKIESIAELQPKPYNPKKMYLTENYIAVVRRTDFLEATGLDLLHLGNNRISMIQDRAFGDLTNLRRLYLNGNRIERLSPELFYGLQSLQYLFLQYNLIREIQSGTFDPVPNLQLLFLNNNLLQAMPSGVFSGLTLLRLNLRSNHFTSLPVSGVLDQLKSLIQIDLHDNPWDCTCDIVGMKLWVEQLKVGVLVDEVICKAPKKFAETDMRSIKSELLCPDYSDVVVSTPTPSSIQVPARTSAVTPAVRLNSTGAPASLGAGGGASSVPLSVLILSLLLVFIMSVFVAAGLFVLVMKRRKKNQSDHTSTNNSDVSSFNMQYSVYGGGGGTGGHPHAHVHHRGPALPKVKTPAGHVYEYIPHPLGHMCKNPIYRSREGNSVEDYKDLHELKVTYSSNHHLQQQQQPPPPPQQPQQQPPPQLQLQPGEEERRESHHLRSPAYSVSTIEPREDLLSPVQDADRFYRGILEPDKHCSTTPAGNSLPEYPKFPCSPAAYTFSPNYDLRRPHQYLHPGAGDSRLREPVLYSPPSAVFVEPNRNEYLELKAKLNVEPDYLEVLEKQTTFSQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FFN0-1", "uniprot_id": "E7FFN0_DANRE", "id": "E7FFN0-1", "name": "", "aln": "--MTANTSAQPPSIIINMHMWILAVSSLAT---FFSLTEMFDIYGDICGGLCVCEERDGIFTASCENRGINSLSEVTPLHFTAYHLLLTGNLLKKVSLNDFLHYEGLTILHLGNNDICEIEAGAFNGLQGLKRLHLNNNKIEALKDDTFLGLESLEYLQIDYNYISHIEPNALSALRHLEVLILNDNLLSALPHNIFQYVPLTHLDLRGNQLKVLPYSGLLEHLSRIVELQLEENAWNCSCELIALKTWLESISYTALVGDVVCETPFRLHGRDLDEISKQELCPRRAIAEYEMHAEMAHSSETVSKTTPATAG-FASST------ILRSTKSSRLSGKLRVKPTSRSSSSKP--QNYGPMLAYQTKSPVPLDCPNTCTCNLQISDLGLNVNCQERKIESISDLDPKPYNPKKMYLTGNYISSVCSSDFSGATGLDLLHLGNNRIAVVHDKTFGQLIHLRRLYLNGNLIERLTEDMFYGLQSLQFLYLEYNVIREIAVGTFQQLPNLQLLFLNNNLLKTLHLGIFDGLNLARLNLRSNHFRTLPVIGVLDELASLIQIDLFENPWDCSCSILDMKNWLEQLSAGTVVNTVICESPPRLSGEDMRYIRSSHICPESSIAQSSAVPPSEESFPGSTITLETALDFDTQYP-----------AVPLSVLILALLLLFILSVFIAAGLFAVIMKRRKKSERSASVT--------------------------ASAIYTERANMKSRTSAGHVYEYIPPSAENAAKNGRYNP---SAIENYRDFEELNRVLASN----------------------------SDEEIR--SNAISSEFSAGTPDP-LNRNSPLLDDNYFYRDILARDQQASYR---------GHLPCKHGTH---ADFDVG--HQYLNP---ERVQQTMVYCSSPTTVYIEPNRSECWELRAKLHFEPDYLEVHEKRTTFTQF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : .: :** *:* . ::*. .:* :* :* **:**.. * ***:***:*.******* ****::* :*. *****:****::: *:*::* * :*****.* * :**:***:**:**:********:* *:********.*****:****** *****:. *: *:**********:**:*:*::***********:**:*** ***:*:.::********.********:** **:****:*********************:********* *::***:.: . *: :****:.. .*:*: *:..*.:* ..* **:****..*.. .**** :**********:**.:*:**********************::*:************ ***: * :** **************::::*::**:* :********* ****: ::********:*:*:**:**** ***: :*************::: *:*.**.* ********* :*** ****:* *******.:*****:*.*:.** *:***..*.:*: ***::* ::: *** *:*. :**: * . *: .**. ..*. * :: .*: ::: . :********:***:**:***:*****.::******.: . : * * . : * * :*.********* . : .** *.. .::*:*:*:.**: . :** .:** * : *. :*..* :* : **: * : ***.** *::.* ::**. .:: .::*: ****:* : : * *.*::*::****.* **:***:.******* **:***:**", "identical_positions": 495, "similar_positions": 232, "identity": "51.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-58", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C0P5-1", "uniprot_id": "COR2A_MOUSE", "id": "Q8C0P5-1", "name": "Coronin-2A", "aln": "MSWHPQYRSSKFRHVYGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQTGKLDPHYPKVCGHRGNVLDIKWNPFNDFEIASCSEDATIKIWNIPKQLLTRNLTTYRKE---------LIGHARRVGLVEWHPTTANILFSAGYDYKVMVWNLDTKDSVIAGPVKTINCHQDVILSMSFNTNGSLLATTCKDRKIRIVDPRLGIVLQEA-SYKGHRANKVLFLGSLKKLLSTGTSRWNNRQMALWDQENLSVPLTE--EDLDGSSGVLFPFFDSDTSMLYIVGKGDGNIRYYEVSMEKPHLTYLTEYRSYNPQKGIGIMPKRGLDVSSCEIFRFYKLITTKSLIEPVSMIVPRR-SESYQEDIYPPTAAAQPSLTAHEWLSGM-NRGPIMMSLR------------------------------------------------------------------------------------------------------------PGSELLDSQTLPPERPLSNSMVQVSPQPLEPMKQPAEDGDQAPFSLLEEKLAKWTAEHHLGEK-SCLTNGFDVFECSPPKTENELLQMFYRQ------QEEIRRLRELLIQREVQTKQLELEIKNLRMALGQL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q92828-1", "uniprot_id": "COR2A_HUMAN", "id": "Q92828-1", "name": "Coronin-2A", "aln": "MSWHPQYRSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQTGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKE---------LVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLATTCKDRKIRVIDPRAGTVLQEA-SYKGHRASKVLFLGNLKKLMSTGTSRWNNRQVALWDQDNLSVPLME--EDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEVSADKPHLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRR-SESYQEDIYPPTAGAQPSLTAQEWLSGM-NRDPILVSLR------------------------------------------------------------------------------------------------------------PGSELLRPHPLPAERPIFNSMAPASPRLLNQTEKLAAEDGWRSSSLLEEKMPRWAAEHRLEEKKTWLTNGFDVFECPPPKTENELLQMFYRQ------QEEIRRLRELLTQREVQAKQLELEIKNLRMGSEQL---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IMS5-1", "uniprot_id": "A0AC58IMS5_DANRE", "id": "A0AC58IMS5-1", "name": "Coronin", "aln": "MSQH-SFRASPFHHVIGKAAVKGRSYHGLSITRSVQDNHFCAVNPRFIAVVTECTGGGAFIVISVRHTGRVSPLHARVCGHSARVLDVKWDPFNDLRIASCSEDCTVKVWNIPPSGLKADLMLPSKD---------LLAHSRRVSLIEWHPTARDLLLSSAYDCKVFMWRLDSSD----VPVIVINTHCELVLCLSFNADGSLLATACKDKKIRIIEPRTGRVLQES-RWASHKVSRILFLWDLKMLLSTGHSCWNQRQFVLWDLEDLSEPLLE--EDLDGGSGVIFPFYDADTHMLYLAGKGDGNIRYYAVSAVKPYVHFLSEYQSSSPQSGLGVMPKRGLNIRVCEVFRFYRLLTVKDLLEPLSFCVPRKQSEGFPEDIYPMTAANEPAMTANEWLMGQ-NKGPLLMSLR------------------------------------------------------------------------------------------------------------PKSEWFDPCLTETEPAANQNVEQPPPDLLADLRDWTDDDTQSQ---------NWTSFSVSGAEACAPETEVAVPIESLIYPEEEEEEDCKPG------SADRKRPQKILP----AVQLLCFSMSRLPMSLCGFR--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06440-1", "uniprot_id": "CORO_YEAST", "id": "Q06440-1", "name": "Coronin-like protein", "aln": "-MSGKFVRASKYRHVFGQAAKKELQYEKLKVTNNAWDSNLLKTNGKFIAVNWNASGGGAFAVIPIEEVGKAPDQVPLFRGHTAQVLDTDFDPFNDHRIASGSDDSKIGIWDIPENYKFHDHVDEDGEPIDIKPVKFLTGHARKVGHVLYHPVAENVLASSSGDYTVKLWNVETGKD------MITLKHPDMVTSMSFSYDGNYLATVARDKKLRVWNIREEKIVSEGPAHTGAKNQRVVWLGNSDRLATTGFSKLSDRQIGIWDAFNIEKGDLGGFYTVDQSSGILMPFYDEGNKILYLVGKGDGNIRYYEFQNDE--LFELSEFQSTEAQRGFAVAPKRMVNVKENEVLKGFKTVVDQR-IEPVSFFVPRR-SEEFQEDIYPDAPSNKPALTAEEWFSGKSVEGPILVSMRSIYDGSAPSFHEAKRPQQPTTQETALEEKKEQPKVEKPISESEKEVKQEAPKSPSPLKSASSSSTINHVLKEDNSINKLLKKSSDIDQVNNAEDPSRDTSGWEEADDEPAPIKIETPVTPTETKKDRTPKVEPSKELKPEPVSIATDRKQEQSLPQEEKSSEKTKSPEQEKSATPPSSITAAKTAITASSKEEPSAARTSPKSLGLKKSVEKLSTLVLQLEDVVDKLTKANLDKDERLLKLEQKIGELSK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:* ::** *:.* * *. : :*... *.:: .* :**** :.:***** **.:...*: . . ** ..*** .::**:* .*** *:*..: :*.** . : : * .*:*:*. : :**.: ::* *:. * .* :*.::: . * ::: .:**. :*. ***..:*:*:*: : * ::.*. . : .::::* . . * :** * .:**. :** ::. :* .**:::**:* .. :**:.********** .. : : *:*::* ..* *:.: *** ::: *::: :: :. : :**:*: ***: ** : ***** :.. :*::**.**: * ..*:::*:* * . : . .* .. .. * . : : . . . . ..:* . . . .: :: .. * : ", "identical_positions": 125, "similar_positions": 179, "identity": "18.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-60", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7D7-1", "uniprot_id": "D4A7D7_RAT", "id": "D4A7D7-1", "name": "GDH/6PGL endoplasmic bifunctional protein", "aln": "MKCTGIWKMLVAAVCLALLG---CLQAQEFRGHVSIILLGATGDLAKKYLWQGLFQLYLDEAGKGHSFSFHGAALTAPQQGQKLMDKALESLSCPKDLVPSRCDELKAQFLQLSQYRQLKTVEDYQTLNKDIETQVQQDGLWEAGRVFYFSVPPFAYADIARNINSSCRPHPGAWLRVVFEKPFGHDHLSAQQLASELGSFFQEEEMYRVDHYLGKQAVAQILPFRDQNRKALDGLWNRHHVERVEIILKETVDAGGRASFYEEYGVIRDTLQNHLTEILTLVAMELPPNISSSAAVLQHKLQAFQALRGLQKSNAILGQYQAYSGQVRQELQKPDGFQSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRILFKNRAYCTQGERHWVPERSRCLPQQIVFYIGHGELGHPAILVSKNLFKPSLPAQ-SWKGVQDQPGLHLFGRPLSDYYAYRPVREQDAYSTLLSHIFHCRKESFITTENLLASWVFWTPLLDSLSFEVPRLYPGGAENDHLLDFEFSGGQLTFSQQQLEVLMPELGSVPKPSDFQVLRAQYRKSPLITAWPEELISKLANDIEAAAVQAVRRFGKFHLALSGGSSPIALFQQLATGHYSFPWAYTHLWLVDERCVPLSDPDSNFQGLQAHLLQHVRVPYYNIHPMPVHLHQRLCAEEDQGAQTYASEISALVANSSFDLVLLGMGTDGHTASLFPQSPRGLDGDQLVVLTESPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREITTLVSRVGHEPKKWPISGVVPLSGQLVWYMDYEAFLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CFX1-1", "uniprot_id": "G6PE_MOUSE", "id": "Q8CFX1-1", "name": "GDH/6PGL endoplasmic bifunctional protein", "aln": "--------MLLAAMCLALLG---CLQAQELKGHVSIILLGATGDLAKKYLWQGLFQLYLDEAGKGHSFSFHGAALTAPQQGQKLMDKVLESLSCPKDLVPSRCDELKGQFLQLSQYRQLKTVEDYQTLNKDIETQVQQDGLWEAGRIFYFSVPPFAYADIARNINSSCRPHPGAWLRVVFEKPFGHDHLSAQQLASELGSFFQEEEMYRVDHYLGKQAVAQILPFRDQNRKALDGLWNRHHVERVEIILKETIDAEGRASFYEEYGVIRDTLQNHLTEILTLVAMELPLNISSSAAVLQHKLWAFQALRGLQKSSAILGQYQAYSGQVRRELQKPDGFQSLTPTFAGVLVHIDNLRWEGVPFILMSGKALDERVGYVRIVFKNRAYCTQSERHWVPEQSRCLPQQIIFYIGHGELGHPAILVSRNLFKPSLPTQ-KWKEVQDQPGLRLFGRPLSDYYAYRPVREQDAYSTLLSHIFHCRKESFITTENLLASWVFWTPLLDSLAFEVPRPYPGGAENGQLLDFEFSGGQLTFSQQQLEVLIPDLGSVPKPSDFQVLGARYRQSPLITAWPEELISKLASDIEAAAVQAVRHFGKFHLALSGGSSPIALFQQLATGHYSFPWAHTHLWLVDERCVPLSDPDSNFQGLQAHLLQHVRVPYYNIHPMPVHLHQRLCAEEDQGAQTYASEISALVANSSFDLVLLGMGTDGHTASLFPQSPTGLDGDQLVVLTESPFRPHQRMSLSLPLINRAKKVAVLVMGRTKREITTLVSRVGHEPKKWPISGVVPLSGQLVWYMDYEAFLG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95479-1", "uniprot_id": "G6PE_HUMAN", "id": "O95479-1", "name": "GDH/6PGL endoplasmic bifunctional protein", "aln": "-----MWNMLIVAMCLALLG---CLQAQELQGHVSIILLGATGDLAKKYLWQGLFQLYLDEAGRGHSFSFHGAALTAPKQGQELMAKALESLSCPKDMAPSHCAEHKDQFLQLSQYRQLKTAEDYQALNKDIEAQLQHAGLREAGRIFYFSVPPFAYEDIARNINSSCRPGPGAWLRVVLEKPFGHDHFSAQQLATELGTFFQEEEMYRVDHYLGKQAVAQILPFRDQNRKALDGLWNRHHVERVEIIMKETVDAEGRTSFYEEYGVIRDVLQNHLTEVLTLVAMELPHNVSSAEAVLRHKLQVFQALRGLQRGSAVVGQYQSYSEQVRRELQKPDSFHSLTPTFAAVLVHIDNLRWEGVPFILMSGKALDERVGYARILFKNQACCVQSEKHWAAAQSQCLPRQLVFHIGHGDLGSPAVLVSRNLFRPSLPS--SWKEMEGPPGLRLFGSPLSDYYAYSPVRERDAHSVLLSHIFHGRKNFFITTENLLASWNFWTPLLESLAHKAPRLYPGGAENGRLLDFEFSSGRLFFSQQQPEQLVPGPGPAPMPSDFQVLRAKYRESPLVSAWSEELISKLANDIEATAVRAVRRFGQFHLALSGGSSPVALFQQLATAHYGFPWAHTHLWLVDERCVPLSDPESNFQGLQAHLLQHVRIPYYNIHPMPVHLQQRLCAEEDQGAQIYAREISALVANSSFDLVLLGMGADGHTASLFPQSPTGLDGEQLVVLTTSPSQPHRRMSLSLPLINRAKKVAVLVMGRMKREITTLVSRVGHEPKKWPISGVLPHSGQLVWYMDYDAFLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FGT2-1", "uniprot_id": "E7FGT2_DANRE", "id": "E7FGT2-1", "name": "", "aln": "-MLRIRWELLLMAIICGQRGSADNHEAKQSLGHVTVVVVGGTGDLARKYLWQGFFQLYADQVGKGHSFSFYGGGLSPAEKGTPVLFGILKELACPPELTAERCALVKEQFLHLSRYHQLKTAEDYEKLCQQIKQQVGQESMTEAGRLFYLSVPAFAYAEIAERINNTCRPPSDAWLRVVLEKPFGHDFASAQLLDKKLSGQLKEEEMYRIDHYLGKQVVSKILPFRKENKKLLDPIWNKHHIERIEIVLKETLDAKGRIQFYDQYGVIRDVLQNHLTEVMTLMLMNLPANLSNSKEILLNKLHFLASLQHIDNSNAVVGQYQAYNGEVQAELNKTKDYFSLTPTFAGVVIHVDNAQYEGIPIFMTSGKALDERVSYARVLFKSDVFCVQD-----PNNVQCKSKQIIFYLGHGNLQYPSILVSKNLLKPEIVSSGDWKEVTEYKEVNLLGLPLSDYYIQSPVAPREAYGELISHVFFGRKDSFISAEGLLASWAFWTPLLESLSHVYPRIYPGGVSNGNLLNFQLRGHQIAFSHEAVVNVIN----RGAEENFQVMQGKYRSSEMISAWAQELVERLASDLLLAAEEAIRREGQFHLALSGGSSPVALLRALALNLYTFPWRNTHIWQVDERCVPHTESGSNFRSIHDLLLQHIRIPYFNIHPMPVHLTQRLCVEEDGGATLYEKEIQKHVNASSFHYILLGVGQDGHTASLFQDTKLESDGERLVTLTESPIKPHQRMSLTFTAINKARRVGVLVMGKSKHELVTQLSRIKGESSRYPITKVQPNNGSLIWYIDYDALLG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: *: . * :*:: ***:::::*.*****:******:**** *:.*:******:*..*:..::* :: *:.*:** ::...:* * ***:**:*:****.***: * ::*: *: : .: ****:**:***.*** :**..**.:*** ..******:*******. *** * .:*. ::******:*******.*::*****.:*:* ** :**:**:**:**::***:** ** .**::******.*******::**: *:** *:*.: :* :** : :*: ::...*::****:*. :*: **:*...: *******.*::*:** ::**:*::: *********.*.*::**. . *.*. . . :* .:*::*::***:* *::***:**::*.: : .** : :.*:* ****** ** ::*:. *:**:*. **: **::*.***** ******:**:. ** ****..*..**:*:: . :: **:: :: .:***: .:**.* :::**.:**:.:**.*: :* .*:*: *:***********:**:: ** * *** **:* ******* ::. ***:.:: ****:*:**:********* ****.*** ** * **. * ***. :***:* ******** :: **::**.** ** :**:****::. **:*::*.*****: *:*:.* :**: *..::**: * * .*.*:**:**:*:**", "identical_positions": 392, "similar_positions": 252, "identity": "48.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-61", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H936-1", "uniprot_id": "GHC1_HUMAN", "id": "Q9H936-1", "name": "Mitochondrial glutamate carrier 1", "aln": "MADKQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQNGQRVYTSMSDCLIKTVRSEGYFGMYRGAAVNLTLVTPEKAIKLAANDFFRHQLSKDGQKLTLLKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTATQLTRDLLRSRGIAGLYKGLGATLLRDVPFSVVYFPLFANLNQLGRPASEEKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQSLQRGVNEDTYSGILDCARKILRHEGPSAFLKGAYCRALVIAPLFGIAQVVYFLGIAESLLGLLQDPQA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D6M3-1", "uniprot_id": "GHC1_MOUSE", "id": "Q9D6M3-1", "name": "Mitochondrial glutamate carrier 1", "aln": "MADKQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQNGQRMYASMSDCLIKTIRSEGYFGMYRGAAVNLTLVTPEKAIKLAANDFFRHQLSKDGQKLTLPKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKILAAQAQLSAQGGAQPSVEAPAPPRPTATQLTRDLLRNHGIAGLYKGLGATLLRDVPFSIVYFPLFANLNQLGRPSSEEKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQSLERGVNEDTYSGFLDCARKIWRHEGPSAFLKGAYCRALVIAPLFGIAQVVYFLGIAESLLGLLQEPQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F8W494-1", "uniprot_id": "F8W494_DANRE", "id": "F8W494-1", "name": "Mitochondrial glutamate carrier 1", "aln": "MADKQISLPAKLINGGVAGLIGVTCVFPIDLAKTRLQNQQNGSRLYTSMSDCLIKTIRSEGYFGMYRGAAVNLTLVTPEKAIKLAANDFFRHHFSKDGQKLTLLKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKLMP---QAVTPGGP---VEMKS---PTAMQLTRQLLKEKGIAGLYKGLGATLLRDVPFSIIYFPLFANLNNLGKKGGDGPAPFYVSFISGCIAGSTAAVAVNPVDVIKTRLQSLTRGSEEDSYSGVTDCIRKILRNEGPAAFLKGAYCRALVIAPLFGIAQVVYFLGVGEFILSHLPKRNN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************:*************************.*:*:*********:***********************************::********* **************************************::. * : **. ** : *** ****:**:.:********************::*********:**: ..: :******::**:***:******* **:******* ** :**:***. ** *** *:***:***************************:.* :*. * . : ", "identical_positions": 252, "similar_positions": 41, "identity": "78.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-64", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8WXH2-1", "uniprot_id": "JPH3_HUMAN", "id": "Q8WXH2-1", "name": "Junctophilin-3", "aln": "MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECAGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGTALHPDAS--PAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWASNRRHGYGCMTFPDGTKEEGKYKQNILVGGKRKNLIPLRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITAKEFSPSFQHRENGLEYQRPKRQ-TSCDDIEVLSTGTPLQQESPELYRKGTTPSDLTPDDSPLQSFPTSPAATPPPAPAARNKVAHFSRQVSVDEERGGDIQMLLEGRAGDCARS---SWGEEQAGGSRGVRSGALRGGLL-----------------VDDFRTRGSGRK-------------QPGNPKP----------------RERRTES----------------PPVFTWTSHHRASNHSPGGSRLLELQ------------------------EEKLSNYRMEMKPLLR---------------------------------------------METHPQKR------------RYSKGGACRGLGDDHRPE-DRGFGVQRLRSKAQNKENFRPAS--SAEPAVQKLASLRLGG-AEPRLLRWDLTFSPPQKSLPVALESDEENGDELKSSTGSAPILVVMVILLNIGVAILFINFFI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9ET77-1", "uniprot_id": "JPH3_MOUSE", "id": "Q9ET77-1", "name": "Junctophilin-3", "aln": "MSSGGRFNFDDGGSYCGGWEDGKAHGHGVCTGPKGQGEYTGSWSHGFEVLGVYTWPSGNTYQGTWAQGKRHGIGLESKGKWVYKGEWTHGFKGRYGVRECTGNGAKYEGTWSNGLQDGYGTETYSDGGTYQGQWVGGMRQGYGVRQSVPYGMAAVIRSPLRTSINSLRSEHTNGAALHPDAS--PAVAGSPAVSRGGFVLVAHSDSEILKSKKKGLFRRSLLSGLKLRKSESKSSLASQRSKQSSFRSEAGMSTVSSTASDIHSTISLGEAEAELAVIEDDIDATTTETYVGEWKNDKRSGFGVSQRSDGLKYEGEWVSNRRHGYGCMTFPDGTKEEGKYKQNVLVSGKRKNLIPLRASKIREKVDRAVEAAERAATIAKQKAEIAASRTSHSRAKAEAALTAAQKAQEEARIARITAKEFSPSFQHRENGLEYQRPKHQ-MSCDDIEVLSTGTPLQQESPELYRKGTTPSDLTPDDSPLQSFPASPTSTPPPAPASRTKMAHFSRQVSVDEERSGDIQMLLEGRGGDYARN---SWGEEKAGASRGIRSGALRSGQP-----------------TEDFRTRGSGHK-------------QPGNPKP----------------RERRTES----------------PTTFSWTSHHRAGNPCSGGPKLLEPD------------------------EEQLSNYKLEMKPLLR---------------------------------------------MDACPQDT------------HPQRRRHSRGAGG------DRGFGLQRLRSKSQNKENLRPAS--SAEPTVQKLESLRLGDRPEPRLLRWDLTFSPPQKSLPVALESDEETGDELKSSTGSAPILVVMVILLNIGVAILFINFFI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F2R3-1", "uniprot_id": "E7F2R3_DANRE", "id": "E7F2R3-1", "name": "", "aln": "MSTGGRFDFDDGGSYCGGWEQGKAHGRGVCTGPQGQGEYAGAWSHGFEVLGVYTWPSGNSYKGTWAQGKRHGIGVESKGRWEYKGEWTQGFKGRYGKLESTSSGSRYEGTWSNGLQDGYGSETYSDGGTYQGQWLSGLRHGYGVRQSVPYGMAAIIFSPMCTSINSLRSDHSEGAPTPEDGSGVSGVSGSP-VGRSGFVLCAHSEADRHR-KRKGRFRQSILSGLKLRRSESKSSLASQLSKQSSFCSEAGMSTVSSAASDINSNVSLGEAEAG-----GSVDATVTETYAGEWRNDMRTGWGVSHRSDGLHFEGEWFGNKRHGYGCTTFPDGTKEEGKYKQNVLVSGKRKNLIPLRTSKIREKVDRALEAAEKAADIAKQKAEIALSRMSHARGKAEAAEGVAQRALEECRLARAIAKELSPSFHHYGNGLECQRPKHHDRKEKDHEVVSTGT----DSPELCTPDTTPPVQTPDLSPVLSSPSSPPCSPP---THRNRNACFMRQSAVDEQGGAEIQVLVEGRGIDSTRAGANSWTAEMYPHRRGSKGESSRSTTPSLLEEEISHINGHENSTHHPWENGSSNHKPIEHMAPEKVWDQMSSNQKPWKHVSLNQKTREHAISREREREHKPSNHNSVDCESSKFKPQVHIYSNHKSAGHNNLSNHKTNEHASTNHKPKEFISAHEKPHVSYHYNPQEHVSSYHKQHEHVHSNHKPRKSFTNHTIGEPSLNAYQLSDRGANNSTLEWTVENNSQWISSHSHPQEKEGENDYRVEMRFQPLDSLSQQNFGSGMKCSGLQGHNLQRLRQRNQEGKEWGLAAREGSMDSVQMLDTLNVGVDVEEWPLHRDITLSPPLTSSLEPLEHEGEQLNLMKTNSGSSSVLVVMVILLNIGVAILFIHFFI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:****:************:*****:******:*****:*:*****************:*:************:****:* ******:******* *.:..*::**************:*************:.*:*:**************:* **: ********:*::*:. *.* ..*:*** *.*.**** ***::: : *:** **:*:*******:********** ****** **********:****:*.:******* ..:***.****.***:** *:*:***:*****::**** .*:****** ***************:**.**********:**********:****:** ********* ** **:*.***** .**:* **.*:** ***:****:* **** ****:: . .* **:**** :**** .***. *** **: * *:**..:** : *.: * * ** :***: ..:**:*:***. * :* ** * ** :. : *. . :.. .*.:* ..* ** ***. * * .. ::.*: *.: .. : * :*::*.*: : : : .: **. : :. *. :*..:****.: *: :: *: .: :** * :*.:* * *: *:*:*** .* .** : * : :*:.:**:.:*****************:***", "identical_positions": 438, "similar_positions": 170, "identity": "48.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-66", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H936-1", "uniprot_id": "GHC1_HUMAN", "id": "Q9H936-1", "name": "Mitochondrial glutamate carrier 1", "aln": "MADKQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQNGQRVYTSMSDCLIKTVRSEGYFGMYRGAAVNLTLVTPEKAIKLAANDFFRHQLSKDGQKLTLLKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKILAAQGQLSAQGGAQPSVEAPAAPRPTATQLTRDLLRSRGIAGLYKGLGATLLRDVPFSVVYFPLFANLNQLGRPASEEKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQSLQRGVNEDTYSGILDCARKILRHEGPSAFLKGAYCRALVIAPLFGIAQVVYFLGIAESLLGLLQDPQA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D6M3-1", "uniprot_id": "GHC1_MOUSE", "id": "Q9D6M3-1", "name": "Mitochondrial glutamate carrier 1", "aln": "MADKQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQNGQRMYASMSDCLIKTIRSEGYFGMYRGAAVNLTLVTPEKAIKLAANDFFRHQLSKDGQKLTLPKEMLAGCGAGTCQVIVTTPMEMLKIQLQDAGRIAAQRKILAAQAQLSAQGGAQPSVEAPAPPRPTATQLTRDLLRNHGIAGLYKGLGATLLRDVPFSIVYFPLFANLNQLGRPSSEEKSPFYVSFLAGCVAGSAAAVAVNPCDVVKTRLQSLERGVNEDTYSGFLDCARKIWRHEGPSAFLKGAYCRALVIAPLFGIAQVVYFLGIAESLLGLLQEPQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F8W3S7-1", "uniprot_id": "F8W3S7_DANRE", "id": "F8W3S7-1", "name": "Mitochondrial glutamate carrier 1", "aln": "MADNQISLPAKLINGGIAGLIGVTCVFPIDLAKTRLQNQQNGSRVYTNMSDCLMKTVRSEGFTGMYRGAAVNLALVTPEKAIKLVANDFFRQQLSKDGEKLTLVREMLAGCGAGTCQVIITTPMEMLKIQLQDAGRLEAQRKMIGPD---AVRGRAKDRTVHLKSP--SALQLSRNLLKHKGIAGLYTGLGATLLRDVPFSIIYFPLFANLNSLGRRNADGSAPFYISFLSGCFAGCAAAVAVNPVDVIKTRLQSLSRGHHEDTYSGVRDCISKILRHEGPSAFLKGSYCRALVIAPLFGIVQVVYFLGVGEFVLSLLHGQIH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:**************************************.*:*:.*****:**:****: **********:**********.******:******:**** :**************:****************: ****::..: :.:* *: . .* :* **:*:**: :******.*************::*********.*** :: .:***:***:**.**.******** **:*******.** :******. ** ** ***********:*************.*******:.* :*.**: ", "identical_positions": 238, "similar_positions": 54, "identity": "73.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-67", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BMC0-1", "uniprot_id": "LPAR6_MOUSE", "id": "Q8BMC0-1", "name": "Lysophosphatidic acid receptor 6", "aln": "MVSSNGSQCPYDDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICALKVRNETTTYMINLAMSDLLFVFTLPFRIFYFATRNWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCIAVWFTVMGGSAPAVFFQSTHSQGNNTSEACFENFPAATWKTYLSRIVIFIEIVGFFIPLILNVTCSSMVLRTLNKPVTLSRS-KMNKTKVLKMIFVHLVIFCFCFVPYNINLILYSLMRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNSIKMKNWSVRRSDSRFSEVQGTEN--FIQHNLQTLKNKIFDNESAI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43657-1", "uniprot_id": "LPAR6_HUMAN", "id": "P43657-1", "name": "Lysophosphatidic acid receptor 6", "aln": "MVSVNSSHCFYNDSFKYTLYGCMFSMVFVLGLISNCVAIYIFICVLKVRNETTTYMINLAMSDLLFVFTLPFRIFYFTTRNWPFGDLLCKISVMLFYTNMYGSILFLTCISVDRFLAIVYPFKSKTLRTKRNAKIVCTGVWLTVIGGSAPAVFVQSTHSQGNNASEACFENFPEATWKTYLSRIVIFIEIVGFFIPLILNVTCSSMVLKTLTKPVTLSRS-KINKTKVLKMIFVHLIIFCFCFVPYNINLILYSLVRTQTFVNCSVVAAVRTMYPITLCIAVSNCCFDPIVYYFTSDTIQNSIKMKNWSVRRSDFRFSEVHGAEN--FIQHNLQTLKSKIFDNESAA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WDA3-1", "uniprot_id": "X1WDA3_DANRE", "id": "X1WDA3-1", "name": "", "aln": "MMTER-SNCT-NDSFKYVLYSSVFSIVFILGLLFNMVAMYIFVCRLKMRNETTTYMMNLVVSDSLFVVSLPFRTFYFINRQWPFGDALCKISVTLFYTNMYGSILFLTCISVDRFLAIVYPFASRTLRTKRNAKIACGVIWVVLLSGGLTAGFVMDITSHKNET--YCFENYSKSQWKSQVSKVVVFMETVGFLIPLMINFICSVKVLQTLRHPETISRGGQLNKAKILRMIVVHLLIFCFCFIPFNVNLVFYTLVRSEVIQNCTVETVVRTIYPIAFCIAVTNCCFDPVIYYFTSETIQNSMKRKSYGVHKNTLNNTIDNSDYNGRGTIDKITSLTAKFMIEESTI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: . *:* :*****.**..:**:**:***: * **:***:* **:********:**.:** ***.:**** *** .*:***** ****** **************************** *:**********.* :*..::.*. .* *. . *: *:: ****:. : **: :*::*:*:* ***:***::*. ** **:** :* *:**. ::**:*:*:**.***:******:*:*:**::*:*:*::.: **:* :.***:***::****:******::*****:*****:* *.:.*::. . : :. * .:: :*. *:: :**: ", "identical_positions": 192, "similar_positions": 102, "identity": "55.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110408-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P18440-1", "uniprot_id": "ARY1_HUMAN", "id": "P18440-1", "name": "Arylamine N-acetyltransferase 1", "aln": "--------------------MDIEAYLERIGYKKSRNKLDLETLTDILQHQIRAVPFENLNIHCGDAMDLGLEAIFDQVVRRNRGGWCLQVNHLLYWALTTIGFETTMLGGYVYSTPAKKYSTGMIHLLLQVTIDGRNYIVDAGFGRSYQMWQPLELISGKDQPQVPCVFRLTEENGFWYLDQIRREQYIPNEEFLHSDLLEDSKYRKIYSFTLKPRTIEDFESMNTYLQTSPSSVFTSKSFCSLQTPDGVHCLVGFTLTHRRFNYKDNTDLIEFKTLSEEEIEKVLKNIFNISLQRKLVPKHGDRFFTI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11245-1", "uniprot_id": "ARY2_HUMAN", "id": "P11245-1", "name": "Arylamine N-acetyltransferase 2", "aln": "--------------------MDIEAYFERIGYKNSRNKLDLETLTDILEHQIRAVPFENLNMHCGQAMELGLEAIFDHIVRRNRGGWCLQVNQLLYWALTTIGFQTTMLGGYFYIPPVNKYSTGMVHLLLQVTIDGRNYIVDAGSGSSSQMWQPLELISGKDQPQVPCIFCLTEERGIWYLDQIRREQYITNKEFLNSHLLPKKKHQKIYLFTLEPRTIEDFESMNTYLQTSPTSSFITTSFCSLQTPEGVYCLVGFILTYRKFNYKDNTDLVEFKTLTEEEVEEVLRNIFKISLGRNLVPKPGDGSLTI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P50297-1", "uniprot_id": "ARY1_RAT", "id": "P50297-1", "name": "Arylamine N-acetyltransferase 1", "aln": "--------------------MDIEAYFERIGYKNSVNKLDLATLTEVLQHQMRAVPFENLSMHCGEAMCLGLEATFDHIVRKKRGGWCLQVNHLLYWALTKMGFETTMLGGYVYITPVNKYSSEMVHLLVQVTISDRNYIVDSAYGSSYQMWEPLELTSGKDQPQVPAIFRLTEENGTWYLDQIRREQDVPNQEFVNSDLLEKSKYRKIYSFTLEPRTIEDFEYVNTYLQTSPASVFVSTSFCSLQTSEGVCCLIGSTLTSRRFSYKDNVDLVEFKSLTEEEIEDVLKTTFGISLEKKFVPKHGELVFTI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50294-1", "uniprot_id": "ARY1_MOUSE", "id": "P50294-1", "name": "Arylamine N-acetyltransferase 1", "aln": "--------------------MDIEAYFERIGYKNSVNKLDLATLTEVLQHQMRAVPFENLNMHCGEAMHLDLQDIFDHIVRKKRGGWCLQVNHLLYWALTKMGFETTMLGGYVYITPVSKYSSEMVHLLVQVTISDRKYIVDSAYGGSYQMWEPLELTSGKDQPQVPAIFLLTEENGTWYLDQIRREQYVPNEEFVNSDLLEKNKYRKIYSFTLEPRVIEDFEYVNSYLQTSPASVFVSTSFCSLQTSEGVHCLVGSTFTSRRFSYKDDVDLVEFKYVNEEEIEDVLKTAFGISLERKFVPKHGELVFTI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50298-1", "uniprot_id": "ARY2_RAT", "id": "P50298-1", "name": "Arylamine N-acetyltransferase 2", "aln": "--------------------MDIEAYFERIGYQSSRNKLDLEELTEILQHQIRAIPFENLNIHCGESMELNLEVIFDQVVRKKRGGWCLQVNHLLYWALTKMGFEATMLGGYVFNTPANKYSSGMIHLLVQVTLSGKDYIVDAGFGRSYQMWEPLELTSGKDQPQVPAIFRLTEENGTWYLDQIRREQYVPNQEFVNSDLLEKNKYRKIYSFTLEPRTIEDFESINTYLQTSPASLFTSKSFCSLQTLEGVHCLVGSTLTYRRFSYKDNIDLVEFKSLTEEEIEDVLKTIFGVSLERKLVPKHGDRFFTI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50295-1", "uniprot_id": "ARY2_MOUSE", "id": "P50295-1", "name": "Arylamine N-acetyltransferase 2", "aln": "--------------------MDIEAYFERIGYQSTRSKLDLKTLTEILQHQIRAIPFENLNIHCGESMELSLEAIFDQIVRKKRGGWCLQVNHLLYWALTKLGFETTMLGGYVFNTPANKYSSGMIHLLVQVTISGKDYIVDAGFGRSYQMWEPLELTSGKDQPQVPAIFRLTEENGTWYLDQIRREQYVPNQEFINSDLLEKNKYRKIYSFTLEPRTIEDFESMNTYLQTSPASVFTSKSFCSLQTPEGVHCLVGSTLTYRRFSYKDNVDLVEFKSLTEEEIEDVLRTIFGVSLERKLVPKHGDRFFTI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50296-1", "uniprot_id": "ARY3_MOUSE", "id": "P50296-1", "name": "Arylamine N-acetyltransferase 3", "aln": "--------------------MDIEAYFERIGYQKSSNKLDLQTLTEILQHQIRAIPFENLNIHCGKTMELSLEDTFHQIVRKKRGGWCLQVNHLLYWALAMIGFETTMLGGCVYVPSACKYSNTMIHLLLQVTISGKTYIVDSAFPFSCQLWEPLELTSGKDQPQVPAIFHLREENGTWYLEQTKRQEYVSNQEFIDSNFLEKNTHRKIYSFTLEPRTIEDFWSISTYYQVSRTSVMTNTSLCSLHTKDGVHGLMGTILAYKKFNYKDNIDLVEFKTLKEEEIEEVLKSVFGIHLETKLVPKCGNVFFTI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32TTY3-1", "uniprot_id": "A0AB32TTY3_DANRE", "id": "A0AB32TTY3-1", "name": "arylamine N-acetyltransferase", "aln": "MIRHDHLALDTTWRGKKRFIMDLREYLKRIGFTGQLNKPDLDSLFTIHKLHVMSVPFENLSVHNGEKNSMDLRVIYNKIVESNRGGWCCENNLLFSWALKEMGYKSTILSGRVFNSLEQDFLPNDSHLINLVEIDGKQYIADVSFGVSCQIWYPLELISGKDQPQPPGVFRLTNNGEKWILEKTGRKQIIVDNGFADSGLVDKRLIKTIYCFTLTPRVVEYFLKMSVMLQTNPSSLFMLKTICSLQTATGFRALIG--WTYSEVTFKEDSDSVEMKKIPDDEIEAVLKEKFNMVLINKFTPKNNKAFYSI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:. *::***: .* ** * : : :: ::*****.:* *. :.*. :.::*. :***** : * *: *** :*:::*:*.* .: . .: **: * :..: **.* . * *:* **** ******* * :* * :: * *:: *:: : :: * .* :: . :.** *** **.:* * :. *.. :* : .::***:* *. *:* : ...:*:: * :*:* : ::*:* **: * : * ::.** .. :*", "identical_positions": 92, "similar_positions": 96, "identity": "29.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-104", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4G0A6-1", "uniprot_id": "MINY4_HUMAN", "id": "Q4G0A6-1", "name": "Probable ubiquitin carboxyl-terminal hydrolase MINDY-4", "aln": "MDSLFVEEVAASLVREFLSRKGLKKTCVTMDQERPRSDLSINNRNDLRKVLHLEFLYKENKAKENPLKTSLELITRYFLDHFGNTANNFTQDTPIPALSVPKKNNKVPSRCSETTLVNIYDLSDEDAGWRTSLSETSKARHDNLDGDVLGNFVSSKRPPHKSKPMQTVPGETPVLTSAWEKIDKLHS-EPSLDVKRMGENSRPKS--GLIVRGMMSGPIASSPQDSFHRHYLRRSSPSSSSTQPQEESRKVPELFVCT-----QQDILASSNSSPSRTSLGQLSELTVERQKTTASSPPHLPSKRLPPWDRARPRDPSEDTPAVDGSTDTDRMPLKLYLPGGNSRMTQERLERAFKRQGSQPAPVRKNQLLPSDKVDGELGALRLEDVEDELIREEVILSPVPSVLKLQTASKP-IDLSVAKEIKTLLFGSSFCCFNEEWKLQSFSFSNTASLKYGIVQNKGGPCGVLAAVQGCVLQKLLFEGDSKADCAQGLQPSDAHRTRCLVLALADIVWRAGGRERAVVALASRTQQFSPTGKYKADGVLETLTLHSLTCYEDLVTFLQQSIHQFEVGPYGCILLTLSAILSRSTELIRQDFDVPTSHLIGAHGYCTQELVNLLLTGKAVSNVFNDVVELDSGDGNITLLRGIAARSDIGFLSLFEHYNMCQVGCFLKTPRFPIWVVCSESHFSILFSLQPGLLRDWRTERLFDLYYYDGLANQQEQIRLTIDTTQTISEDTDND-----LVPPLELCIRTKWKGASVNWNGSDPIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UQI9-1", "uniprot_id": "MINY4_MOUSE", "id": "Q3UQI9-1", "name": "Probable ubiquitin carboxyl-terminal hydrolase MINDY-4", "aln": "MDSLYVEEVAASLVREFLSRKGLNKTFVTMDQERPRCELSINSRNDLRKVLHLEFLYKENKAKEKPLRTNLELITRYFLDNVGNTDNSESQEVPIPAIPVPKKNNKLPLRHSETTLVNIYDLSDEDTGRRTSWSEAGKARHDSLDGDILGNFVSSKKPSHKSKAAHVDLGDSLPLVPAWEKVDQLHSSEPGIDVKKTMERTRPKS--GLIVRGMMAGPVASSPQDSFRKRSLRRSSALSRKLQTPEEIQQQSEPFVHTPAYLGPQEVPDSSSDSVSRSPLGQLNELSIEKPNVTSS------SQGLSQRDRPRLRSVSEDSPLGYSHTE------------GNSRMAQDQLERAFKRQGVQPPSLRKNQLV-SDRTDDKPDALQLEDVEDELIKEDIVLFPPPSMLKLQTVSKP-IDLSLAKEIKTLLFGSTFCCFSEEWKLQNFSFNDIASLKYGIVQNKGGPCGVLAAVQGCVLQKLLFEGDNRTNSNLRLQPSDAQRTRCLALAIADILWRAGGKEQAVVALASGTPHFSPTGKYKADGVLETLTLYSLTSSEDLVTFIQQSVHQFEAGPYGCILLTLSAILSRSLELVRQDFDVPTSHLIGAHGYCTQELVNLLLTGRAVSNVFNDVVELDSGDGNITLLRGIEARSDIGFLSLFEHYNVCQVGCFLKTPRFPIWVVCSESHFSILFSLQPELLCDWRSERLFDLYYYDGLANQQEEIRLTVDTTKTAPADSCSD-----LVPPLELCIRTKWKGASVNWNGSDPIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F8W526-1", "uniprot_id": "F8W526_DANRE", "id": "F8W526-1", "name": "Ubiquitin carboxyl-terminal hydrolase MINDY", "aln": "MMGKDVEDVSASLVREYLSRKGLKKTIACMDEELPRTHSSVNNRSDLRSILHLEGLYKKNKAEEHPLKSMLEMIVKDRMSEGGKTKGHRQGDVQAHALDQTMS----------SSSIDMTETIKRDESCLHNLSSNNPRLSESSR--VSQVIVSPQTPSEKR---QDKAKTSLDLSSSSRDSLLTMSKEGFLSETKVLDTDSQKNRGSRIRRGIMAGPICSSSQESNRRRPTRKT--ASSVIETMEDCRQASN----------WTNGFNTTNTKSKPSAFLQVESSSISN---------------------LHKGNIDHD---------------------GHERMTKAKQK-------NSAPSLNLDGLH------------VLEMVLDDIEYEESLCDISRKILPEYSLDKTSMDQMTAVALKEIIFGSSMACFTEEWKQQSFTFSDTPGLKYGIVQKKGGPCGVLAAVQACVLEKLLFEESSCDSVDQRLEVSSIVRTKCLYLALADVIWRAGNMNRATVAINTGRSVFTPIGRYKSDGILEMITYVTVETLDDLTLVLEQHVRQFESGPFGCILLTISAILSRTIAIVRSDMDVPTSTLIGAHGYCTQELVNLLLCGRAVSNVFDDEMKLDSGNGNFTLLRGIKTRSDIGLLSLFEHYNICKVGSHLKNPTFPIWVVCSESHFSVLFSLSKDLASDHCTENEFDLYYYDGLANQQEPIRLTVYPHSAAKAAAHNDNTDDDLIPPLELCIRTKWPNAVVNWNDTDPIL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . **:*:******:******:** . **:* ** . *:*.*.***.:**** ***:***:*:**:: **:*.: :.. *:* . :. *: . . :: ::: : ..* . . *. . :. : :**.: *..* : : * .: .. * * :. .: : *. . * **:*:**:.**.*:* ::: *:: * :. *: :: .: : ::. . . :.: *:.. ::.. : . ..* *:.**:: : : ....:. : * ** * *:: *: : .:* : .*. :* * :* ::***::.**.**** *.*:*.: ..*******:************.***:***** .. . *: *. **:** **:**::****. ::*.**: : *:* *:**:**:** :* :: :**. .::* ::*** **:******:******: ::*.*:***** ***************** *:******:* ::****:**:****** :*****:********:*:**..**.* *************:****. * * :*. ************** ****: . .: : .* *:*********** .* ****.:****", "identical_positions": 296, "similar_positions": 204, "identity": "38.39%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-106", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P53667-1", "uniprot_id": "LIMK1_HUMAN", "id": "P53667-1", "name": "LIM domain kinase 1", "aln": "MRLTLLCCTWREERMGEEGSELPVCASCGQRIYDGQYLQALNADWHADCFRCCDCSASLSHQYYEKDGQLFCKKDYWARYGESCHGCSEQITKGLVMVAGELKYHPECFICLTCGTFIGDGDTYTLVEHSKLYCGHCYYQTVVTPVIEQILPDSPGSHLPHTVTLVSIPASSHGKRGLSVSIDPPHGPPGCGTEHSHTVRVQGVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEIDLLIQETSRLLQLTLEHDPHDTLGHG-----LGPETSPLSSPAYTPS-GEAGSSARQKPVLRSCSIDRSPGAGSLGSPASQRKDLGRSESLRVVC--RPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKSMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLMVDEKTQPEG-LRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEHWLETLRMHLAGHLPLGPQLEQLDRGFWETYRR----GESGLPAHPEVPD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P53668-1", "uniprot_id": "LIMK1_MOUSE", "id": "P53668-1", "name": "LIM domain kinase 1", "aln": "MRLTLLCCTWREERMGEEGSELPVCASCGQRIYDGQYLQALNADWHADCFRCCECSVSLSHQYYEKDGQLFCKKDYWARYGESCHGCSEHITKGLVMVAGELKYHPECFICLACGNFIGDGDTYTLVEHSKLYCGQCYYQTVVTPVIEQILPDSPGSHLPHTVTLVSIPASAHGKRGLSVSIDPPHGPPGCGTEHSHTVRVQGVDPGCMSPDVKNSIHVGDRILEINGTPIRNVPLDEIDLLIQETSRLLQLTLEHDPHDSLGHG-----PVSDPSPLSSPVHTPS-GQAASSARQKPVLRSCSIDTSPGTSSLASPASQRKDLGRSESLRVVC--RPHRIFRPSDLIHGEVLGKGCFGQAIKVTHRETGEVMVMKELIRFDEETQRTFLKEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIKNMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENRNVVVADFGLARLMIDEKNQSED-LRSLKKPDRKKRYTVVGNPYWMAPEMINGRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCPPSFFPITVRCCDLDPEKRPSFVKLEQWLETLRMHLSGHLPLGPQLEQLERGFWETYRR----GESSLPAHPEVPD--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FB16-1", "uniprot_id": "E7FB16_DANRE", "id": "E7FB16-1", "name": "LIM domain kinase 1", "aln": "--------------MIKSSQDL-YCRRGGK-------------------ARCCECNSVLADWYYERDGQFFCKKHYLSRFAEQCYGCTESINTGPIMVAGKNKYHPECFLCESCDVFIGDGDSFALVDYTNLYCGQCHYQKVST----QHLAAK-GSPLPHMVTSMSFPPSAESRQGLFFTVEK--------KDKEHLVTVSQLDLHNLSAEVKPLIHVGDRILEINGISVHNIPLNEINLVIHDTEHWLQITIEHNPKDHIKQEDLSGLLGEELDQPGNLGFFPLPNNRQISHRSKNILRSCSIDKVPCLQRHAALLSHRRDINRSESLRFDANDKTQRIFRPSDLIYGEILGKGCFGQAIKVTHLETGEVMVIKELLQFDEETQKTFLKEVKVMRCLEHPNVLKFIGILYKDKRLNLISEYVQGGTLRDTILKMASDHPWNLRVSYAKDIAAGMAYLHSMNVIHRDLNSHNCFVRENQTVVVADFGLAQLVKDEKTSSPGQMSKLNKLGRKKRYTVVGNPYWMAPEMINGKIYDERVDIFSFGIVLCEIIGRVYADPDFLPRTQEYGLNVKEFLERCWSKDCPAAFFPIAVLCCALEAEKRPVFAKLEEWLENVMMHLEMGLPLMSELLKVRQSFWENHSQPRPYGISSKPMESSAFGRS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :...:* * *: ***:*. *:. ***:***:****.* :*:.*.*:**:* *..* :****: *******:* :*. ******:::**::::****:*:**.* * * *. . ** *** ** :*:*.*:..::** .::: .::.* * *. :* :*.:** ************ .::*:**:**:*:*::*.: **:*:**:*:* : : : . .. . * .: * *.* :******* * .: *:*:*:.******. . :.:*********:**:************** *******:***::******:**********************:********:*:**::*****. * .* *::**. ***:*****:*********:**********:****:.*********:*: ***... . : .*:* .*********************: ***:**:************** ****:**** ::****: **:* . :**.:****:* ** *:.**** *.***.***.: *** *** .:* :: :.***.: : * *. * .... . ", "identical_positions": 346, "similar_positions": 162, "identity": "52.27%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-117", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29089-1", "uniprot_id": "AGTRB_RAT", "id": "P29089-1", "name": "Type-1 angiotensin II receptor B", "aln": "MTLNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIYRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFLIILTSYTLIWKALKKAYKIQKN--TPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGIIRDCEIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPTAKSHAGLSTKMSTLSYRPS--DNMSSSAKKSASFFEVE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29755-1", "uniprot_id": "AGTRB_MOUSE", "id": "P29755-1", "name": "Type-1 angiotensin II receptor B", "aln": "MILNSSIEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYQWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFVFPFVIILTSYTLIWKALKKAYKIQKN--TPRNDDIFRIIMAIVLFFFFSWVPHQIFSFLDVLIQLGVIHDCEIADVVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKARSHAGLSTKMSTLSYRPS--DNMSSSARKSAYCFEVE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P25095-1", "uniprot_id": "AGTRA_RAT", "id": "P25095-1", "name": "Type-1 angiotensin II receptor A", "aln": "MALNSSAEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVCAFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKN--KPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCKISDIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPS--DNMSSSAKKPASCFEVE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P29754-1", "uniprot_id": "AGTRA_MOUSE", "id": "P29754-1", "name": "Type-1 angiotensin II receptor A", "aln": "MALNSSTEDGIKRIQDDCPRAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVCAFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKN--KPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCKIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPS--DNMSSAAKKPASCSEVE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30556-1", "uniprot_id": "AGTR1_HUMAN", "id": "P30556-1", "name": "Type-1 angiotensin II receptor", "aln": "MILNSSTEDGIKRIQDDCPKAGRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNYLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLLAGLASLPAIIHRNVFFIENTNITVCAFHYESQNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKN--KPRNDDIFKIIMAIVLFFFFSWIPHQIFTFLDVLIQLGIIRDCRIADIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFLQLLKYIPPKAKSHSNLSTKMSTLSYRPS--DNVSSSTKKPAPCFEVE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5V1-1", "uniprot_id": "A0ACD6B5V1_DANRE", "id": "A0ACD6B5V1-1", "name": "Type-1 angiotensin II receptor", "aln": "MENQTSAMS--EDLHVNCSMSGRHGFIFTFIPVVYGCNFVIGIIGNSMVVAVIFRYMKLKTVANVFVLNLAISDLTFLITLPLWATFTATGYHWIFGAFLCKASAGMVIFNLYTSIFFLTALSIDRYLAIVHPVRSRRQRTLFYANLTCVLIWLFALLLSAPTALSRDVYDIG--NLTLCAVWHSSKQIHFLVTLSVLKSVLGFIVPFLIIITCYCLIGRALLGSRGLLRKSVRSREDETLRMIAATVLAFFVCWAPHQAFHFMELLATLGVVENCQTLDVIDTAMPFTICISYLNSCVNPILYGFVGHNFRKNLLRLLSCGSGEASNRFSINSKIDVNSHCNSGLLNQTSSKNDSASMVKAS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::* . : :: :*. :***.:**.:**.:*. **:**:***:** **: ********.**:****::** **:******.:** *:* ** .*** ::. * ****:*:*:**.************::** :**:: *::**::***:* * * *: : *:*: * *:*:**. :.*:: : : *.: *.:***:.**:**:*.* ** :** : : :: .*:*: :::* * ** **..* *** * *:::* **::.:*. *::*****:****:*:*.*:**::***:*::*:: :*:**. . * .: .:.:*:.. *: * * :*: ...* :..", "identical_positions": 161, "similar_positions": 125, "identity": "44.35%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-118", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23276-1", "uniprot_id": "KELL_HUMAN", "id": "P23276-1", "name": "Kell blood group glycoprotein", "aln": "-----------------MEGGDQSEEEPRERSQ---AGGMGTLWSQESTPEERLPVEGSRP-----WAVARRVLTAILILGLLLCFSVLLFYNFQN----------CGPRPCETSVCLDLRDHYLASGNTSVAPCTDFFSFACGRAKETNN-----SFQELATKNKNRLRRILEVQN---SWHP--------------------------------GSGEEKAFQFYNSCMDTLAIEAAGTGPLRQVIEELGGWRISGKWTSLNFNRTLRLLMSQYGHFPFFRAYLGPHPASPHTP----VIQIDQPEFDVPLKQD---QEQKIYAQIFREYLTYLNQLGTLLGGDPSKVQEHSSLSISITSRLFQFLRPLEQRRAQGKLFQMVTIDQLKEMAPAIDWLSCLQATFTPMSLSPSQSLVVHDVEYLKNMSQLVEEMLLKQRDF----LQSHMILGLVVTLSPALDSQFQEARRKLSQKLRELTEQPPMPARPRWMKCVEETGTFFEPTLAALFVREAFGPSTRSAAMKLFTAIRDALITRLRNLPWMNEETQNMAQDKVAQLQVEMGASEWALKPELARQEYNDIQLGSSFLQSVLSCVRSLRARIVQSFLQPHPQHRWKVSPWDVNAYYSVSDHVVVFPAGLLQPPFFHPGYPRAVNFGAAGSIMAHELLHIFYQLLLPGGCLACDNHALQEAHLCLKRHYAAFPLP---SRTSFNDSLTFLENAADVGGLAIALQAYSKRLLRHHGETVLPSLDLSPQQIFFRSYAQVMCRKPSPQDSHDTHSPPHLRVHGPLSSTPAFARYFRCARGALLNPSSRCQLW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T8H2-1", "uniprot_id": "A0AB32T8H2_DANRE", "id": "A0AB32T8H2-1", "name": "", "aln": "MCDVLFCGFAPLTPLSSYQPGPASHTPLIVKSDDVCAFKFVILKEMVTTPEQQPRSDEPNPVLCNKYKYRRLLLPPFAVSLFATALGLGIYSHLQKTADPWKSKWKSAAPLCLSPACIRASEHFSVAMDPFSRPC-DYFLFACGAGGSSTNRDRQRVKGEVNKHSEVRTRGLIEMRRGTDGWSKSDGQLKTFPDRQTALLTAIKEILEAPDEAVSMGAAEQKAKNFFKSCMNAESREKMGSEPFLTLLQQLGGWAVSGVWNQTDFNSTLALLMGQYSTFPFFNVYVGPEPSEEQSASNRHYIQIDEPHFQFPIEWNSKTQKAKANTRYLRPFYSACGQYLVLLGVPSDRTTQHCGLFVSLSTTLAVATFPLPYRLSQKLLYRRTTIQELQTLAPAVDWLACLQATFQPLLISKSDIVLVHNLPYIIHMSKTIHLWQVQHELMGTGPLNTYMIFSLLQTLIPALDSRFFQIMRNYSIATGDTQEMP------HWWRCVQQT----ERGFDTLLSHAIREKHAQKEAEELIQDVYSSLKKKLTDLSWRDEKESDFILNKINSLNPRISTNTNNLSYTELNHLYEKVILNEEDFFSNYLQILLLEQKSRARLLSLGTQTEG------LSMTPFISGNDIIVPVGMFVSPFFHSSYPRALNYGTLGSLMAKDLLHLLLPDIYT------KAKNPETESLCVWSHYLSVTKGPGWGDAFYLPSSKQQEVWVQYSALQVALDAYKMSFKRYLADSSLP--GFSYVHLFLSSFTKVTCDTDAYREFMP--LEPSFLVTVLCSNSGLCPKPLTCMNKPQSFPAEMCQS-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * *. :*: * : * . :***:: : ..* : * :*..: : : .:.: :: ::*: ... * :..*: :*: .: :. ** *:* **** . .:.* *: .:.: * * ::*::. .* *:.*:** :*::***:: : * *: *: ::::**** :** *.. :** ** ***.**. ****..*:**.*:. ::. ****:*.*:.*:: : *: * :: :* : : .* .*** ..:. :*..* :*::: * ** * :* *:: .**::*: :***:***:****** *: :* *: ::**:: *: :**: :. :::. : *:::**:.*: ** *****:* : *: * : * * :* :**::* * : :*: : ::. * :*: : .:* .:* :*.* :*: .:: :*: .*: .:.:. *. .: *:.: *... : * : *. : :*. .* . :. :*.: ::.*.*:: .****..****:*:*: **:**::***:: : . . : : **: ** :.. . : : * . * .: ..* :**:**. : *: .:: ** .:* ::*: *:::* * . : :: * : * *.: .: : * . . *:. ** ", "identical_positions": 194, "similar_positions": 270, "identity": "23.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-119", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35167-1", "uniprot_id": "COLQ_RAT", "id": "O35167-1", "name": "Acetylcholinesterase collagenic tail peptide", "aln": "MAVLNPMTLGIYLQLFFCSIVSQPTFINSVLPISAALPGLDQKKRGNHKACCLLMPPPPPLFPPP--FFR-GSRSPLLSPDMKN--LLELEASPS--PCMQGSLGSPG---PPGPQGPPGLPGKAGPKGEKGDLGRPGRKGRPGPPGVPGEPGPVGWPGPEGPRGEKGDVGMMGLPGSRGPMGSKGFPGSRGEKGSRGERGDLGPKGEKGFPGFPGMLGQKGEMGPKGESGIAGHRGPTGRPGKRGKQGQKGDSGIMGPPGKPGPSGQPGRQGPPGPPGPPSAGQLVMGLKGERGFPGPPGRCLCGPPANVNNPSYGDPMYGRGSPRVPAIFVVNNQEELEKLNTQNAIAFRRDQRSLYFKDSLGWLPIQLTPFYPVGLHHKAAWHLCGDGVLQP--GEECDDGNPDVSDGCIDCHRAYCGDGYRHRGVEDCDGSDFGYLKCETYLPGSYGELRCTQYCSIDSTPCRYFT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35348-1", "uniprot_id": "COLQ_MOUSE", "id": "O35348-1", "name": "Acetylcholinesterase collagenic tail peptide", "aln": "MVVLNPMTLGIYLQLFFCSIVSQPTFINSVVPISAALPGLDQKKRGSHKACCLLMPPPPPLFPPP--FFR-GSRSPLLSPDMKN--LLELEASPS--PCIQGSLGSPG---PPGPQGPPGLPGKTGPKGEKGDLGRPGRKGRPGPPGVPGMPGPVGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGFPGSRGEKGSRGERGDLGPKGEKGFPGFPGMLGQKGEMGPKGESGLAGHRGPTGRPGKRGKQGQKGDSGIMGPPGKPGPSGQPGRQGPPGPPGPPSAGQLVMGLKGERGFPGPPGRCLCGPPVNVNNPSYGDSMYGRGSPRVPAIFVVNNQEELERLNTQNAIAFRRDQRSLYFKDSLGWLPIQLTPFYPVGYTVKQPG-TCGDGVLQP--GEECDDGNPDVSDGCIDCHRAYCGDGYRHQGVEDCDGSDFGYLTCETYLPGSYGDLRCTQYCSIDSTPCRYFT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y215-1", "uniprot_id": "COLQ_HUMAN", "id": "Q9Y215-1", "name": "Acetylcholinesterase collagenic tail peptide", "aln": "MVVLNPMTLGIYLQLFFLSIVSQPTFINSVLPISAALPSLDQKKRGGHKACCLLTPPPPPLFPPP--FFR-GGRSPLLSPDMKNL-MLELETSQS--PCMQGSLGSPG---PPGPQGPPGLPGKTGPKGEKGELGRPGRKGRPGPPGVPGMPGPIGWPGPEGPRGEKGDLGMMGLPGSRGPMGSKGYPGSRGEKGSRGEKGDLGPKGEKGFPGFPGMLGQKGEMGPKGEPGIAGHRGPTGRPGKRGKQGQKGDSGVMGPPGKPGPSGQPGR---PGPPGPPPAGQLIMGPKGERGFPGPPGRCLCGPTMNVNNPSYGESVYGPSSPRVPVIFVVNNQEELERLNTQNAIAFRRDQRSLYFKDSLGWLPIQLTPFYPVDYTADQHG-TCGDGLLQP--GEECDDGNSDVGDDCIRCHRAYCGDGHRHEGVEDCDGSDFGYLTCETYLPGSYGDLQCTQYCYIDSTPCRYFT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q7Y1-1", "uniprot_id": "F1Q7Y1_DANRE", "id": "F1Q7Y1-1", "name": "", "aln": "---MILFTFGLCFQLLCY--VLSFSYVDDLFPFPTDHQLLETRKK--FNPCCLLSPPPPPLFPPPPSLWRQGSLTKTETSVTANEGFTEEKHNPTTHTCSSGPPGPPGPAGPPGPQGPAGLPGPKGPKGDKGEIGRPGQKGRTGPPGLPGRQGPSGWQGPTGPKGEKGDPGLMGLPGARGPMGPKGLHGFKGEKGSQGFRGEIGLKGDRGSMGLPGMLGQKGEMGPKGEPGSSGNRGPTGRPGKRGKQGSKGDTGAIGPMGPGGPPGAPGH---PGPPGVSASGLYMVGQKGDKGQQGSPGRCSCNVPANPSLDHLHWSIY----PRVPAIFVVNNEQELNRVQTENALAFRKDQRSLYFKDTGGWMPIQLTPFQSMESDPDPEG-FCGDSIVQVENGEECDDGNKVVTDGCVKCKLAYCGDGYRYEEAEECDGKDFGFHTCRSFLPGSYGHLKCTADCFIDSTNCKYFT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :*:*: :**: * . ::::.:.*:.: *: :*: .:.**** ********** ::* *. : :. * : * : . : .* .*. *.** *******.**** ****:**::****:***.****:** ** ** ** **:***** *:*****:*****.** * :*****:* :*::* **::* *:***************.* :*:**************.***:* :** * **.* **: ***** ..:* ::* **::* *.**** *. . * . .:* ****.******::**::::*:**:***:*********: **:******* .: . ***.::* ******** * *.*: *: ******:*:. .*:***.***: .*.::******.*:** * **** *:***", "identical_positions": 246, "similar_positions": 112, "identity": "52.34%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-120", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A7Z6-1", "uniprot_id": "D4A7Z6_RAT", "id": "D4A7Z6-1", "name": "Alpha-tectorin", "aln": "MNYSSLLRIWVSFIFALVRHQAQPRELMYPF--WQNDTRTPKVDDGSSSEIKLAIPVFFFGVPYRTVYVNNNGVVSFNVLVSQFTPESFPLTDGRAFIAPFWADVHNGIRGEIYYRETMDSAILRRATKDIRKYFKDMTTFSATWVFIVTWEEVTFYGGSSTTPVNTFQAVLVSDGSYTFTLFNYYEINWTTGTASGGDPLTGLGGVMAQAGFNGGNLTNFFSLPGSRTPEIVNIQETTNVNVPGRWAFKVDGKEIDPANGCTSRGQFLRRGEVFWDDLNCTIKCRCLDFNNEIYCQEASCSPYEVCEPKGRFFYCSPVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRGGSAVSWVKELSVEVNGYKILIPKGSYGKVKVNDLVTSLPVTLELGAVKIYQSGMSTAVETDFGLLVTFDGQHYASISIPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHTDWKCGSGCIDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDATAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRIQTGCVSTVRCPSFSHYSVCTSSCPDTCSDLTASQNCATPCTEGCECNEGFVLSTSQCVPLHKCGCDFEGHYYTMGEFFWATAN------CTVQCLCEEGGDVYCFNKTCRSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGAAYAFPSELSYTLLKTCPERPE---YLEIDINKRKPDAGPAWLRGVRILVADQEVKIGGVGALEVKLNGQDVELPFFHPSGRLEIHRNK-NSTTVESKGVVSVQYSDVGLLYIRLSTMYFNCTGGLCGFFNANASDEFCLPNGKCTDNLAVFLESWTTFEE--ICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECMT-CTETCETLALG-PICVDSCSEGCQCDEGYALQGSQCVTRSECGCNFEGHQLATNETFWVDQDCQIFCYCNGTDNSVHCETIPCRDDDYCMEESGLYYCQPRTDASCIVSGYGHYLTFDGYPFDFQTSCPLILCTTGS--------------RSISDSFPKFIVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNNERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPGDDLEMPMGLLALSINEFGQSWVKRDTFCQVGCGDRCPSCAKVEG--------------------------------------FSKVQQLCSLIPNQNAGFAKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGVAVTGWRNYTSCSVTCPPNSHYESCVSVCQPRCAAIRLKSDCNHYCVEGCQCDAGYVLNGKSCILPHNCGCYSDGKYYEPKQLFWNGDCTRRCRCFRRNLIQCDPRQCKSDEECALRSGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSSPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDMTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLTPSCNELQFSQYAATCDNVHIQAMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYNHKKFQLCGSLAAYGEACRSFGILSTEWIEKENCSGVVEDPCVGADCPNRTCELDNGGELCGCIEPPPYGNNSHDIIDAEVTCKAAQMEVSISKCKLFQLGFEREGVRINDRQCSGIEGEDFISFQINNTKGNCGNVVQSNGTHIMYKNTIWIESANNTGNIITRDRTINVEFSCAYELDIKISLDSVVKPMLSVINLTVPTQEGSFTTKMALYKNASYKHPYRQGEVVLTTRDVLYVGVFVVGADSTHLILTLNKCYATPSRDSNDKLRYFIIEGGCQNIKDNTIGIEENGVSLTCRFHVTVFKFIGDYDEVHLHCAVSLCDSEKYSCKINCPQNSRIATDYSKEHKEQIISVGPIRRKRLDWCEDN-GGCEQVCTSRVDGPLCSCVTGSLQEDGRSCRASNSSVEPQVWTLLLIMTQISLWHFVYQSGATS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O08523-1", "uniprot_id": "TECTA_MOUSE", "id": "O08523-1", "name": "Alpha-tectorin", "aln": "MNYSSLLRIWVSFIFALVRHQAQPRELMYPF--WQNDTRTPKVDDGSSSEIKLAIPVFFFGVPYRTVYVNNNGVVSFNVLVSQFTPESFPLTDGRAFIAPFWADVHNGIRGEIYYRETMDPAILRRATKDIRKYFKDMTTFSATWVFIVTWEEVTFYGGSSTTPVNTFQAVLVSDGSYTFTLFNYYEINWTTGTASGGDPLTGLGGVMAQAGFNGGNLTNFFSLPGSRTPEIVNIQETTNVNVPGRWAFKVDGKEIDPANGCTSRGQFLRRGEVFWDDLNCTIKCRCLDFNNEIYCQEASCSPYEVCEPKGRFFYCSPVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRGGSAVSWVKELSVEVNGYKILIPKGSYGKVKVNDLVTSLPVTLELGAVKIYQSGMSTAVETDFGLLVTFDGQHYASISIPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKCGSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDATAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRIQTGCVSTVRCPSFSHYSVCTSSCPDTCSDLTASQNCATPCTEGCECNEGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATAN------CTVQCLCEEGGDVYCFNKTCRSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGAAYAFPSELSYTLLKTCPERPE---YLEIDINKKKPDAGPAWLRGVRILVADQEVKIGGVGALEVKLNGQDVELPFFHPSGRLEIHRNK-NSTTVESKGVVSVQYSDVGLLYIRLSTMYFNCTGGLCGFFNANASDEFCLPNGKCTDNLAVFLESWTTFEE--ICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECMT-CTETCETLALG-PICVDSCSEGCQCDEGYALQGSQCVPRSECGCNFEGHQLATNETFWVDQDCQIFCYCNGTDNSVHCETIPCRDDEYCMEESGLYYCQPRTDASCIVSGYGHYLTFDGYPFDFQTSCPLILCTTGS--------------RPISDSFPKFIVTAKNEDRDPSLALWVKQVDVNVFGYSIVIHRAYKHTVLVNNERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNGTYGLCGRYNGNPDDDLEMPMGLPALSINEFGQSWVKRDTFCQVGCGDRCPSCAKVEG--------------------------------------FSKVQQLCSLIPNQNAGFAKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGIAVTGWRNYTSCSVTCPPNSHYESCVSVCQPRCAAIRLKSDCNHYCVEGCQCDAGYVLNGKSCILPHNCGCYSDGKYYEPKQLFWNGDCTRRCRCFRRNLIQCDPRQCKSDEECALRSGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSSPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDMTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAATCDNVHIQAMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYNHKKFQLCGSLAAYGEACRSFGILSTEWIEKENCSGVVEDPCVGADCPNRTCELDNGGELCGCIEPPPYGNNSHDIIDAEVTCKAAQMEVSISKCKLFQLGFEREGVRINDRQCSGIEGEDFISFQINNTKGNCGNIVQSNGTHIMYKNTIWIESANNTGNIITRDRTINVEFSCAYELDIKISLDSVVKPMLSVINLTVPTQEGSFTTKMALYKNASYKHPYRQGEVVLTTRDVLYVGVFVVGADSTHLILTLNKCYATPSRDSNDKLRYFIIEGGCQNIKDNTIGIEENGVSLTCRFHVTVFKFIGDYDEVHLHCAVSLCDSEKYSCKINCPQNSRIATDYSKEHKEQIISVGPIRRKRLDWCEDN-GGCEQICTSRVDGPLCSCVTGSLQEDGRSCRASNSSVELQVWTLLLIMTQISLWHLIYKSGATS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75443-1", "uniprot_id": "TECTA_HUMAN", "id": "O75443-1", "name": "Alpha-tectorin", "aln": "MNYSSFLRIWVSFIFALVQHQAQPRELMYPF--WQNDTKTPKVDDGSSSEIKLAIPVFFFGVPYRTVYVNNNGVVSFNVLVSQFTPESFPLTDGRAFVAPFWADVHNGIRGEIYYRETMEPAILKRATKDIRKYFKDMATFSATWVFIVTWEEVTFYGGSSTTPVNTFQAVLVSDGSYTFTLFNYYEINWTTGTASGGDPLTGLGGVMAQAGFNGGNLTNFFSLPGSRTPEIVNIQETTNVNVPGRWAFKVDGKEIDPANGCTSRGQFLRRGEVFWDDLNCTVKCRCLDFNNEIYCQEASCSPYEVCEPKGKFFYCSAVETSTCVVFGEPHYHTFDGFLFHFQGSCAYLLARQCLQTSSLPFFSVEAKNEHRRGSAVSWVKELSVEVNGYKILIPKGSYGRVKVNDLVTSLPVTLDLGTVKIYQSGISTAVETDFGLLVTFDGQHYASISVPGSYINSTCGLCGNYNKNPLDDFLRPDGRPAMSVLDLGESWRVYHADWKCDSGCVDNCTQCDAATEALYFGSDYCGFLNKTDGPLWECGTVVDPTAFVHSCVYDLCSVRDNGTLLCQAIQAYALVCQALGIPIGDWRTQTGCVSTVQCPSFSHYSVCTSSCPDTCSDLTASRNCATPCTEGCECNQGFVLSTSQCVPLHKCGCDFDGHYYTMGEFFWATAN------CTVQCLCEEGGDVYCFNKTCGSGEVCAVEDGYQGCFPKRETVCLLSQNQVLHTFDGASYAFPSEFSYTLLKTCPERPE---YLEIDINKKKPDAGPAWLRGLRILVADQEVKIGGIGASEVKLNGQEVELPFFHPSGKLEIYRNK-NSTTVESKGVVTVQYSDIGLLYIRLSTTYFNCTGGLCGFYNANASDEFCLPNGKCTDNLAVFLESWTTFEE--ICNGECGDLLKACNNDSELLKFYRSRSRCGIINDPSNSSFLECHGVVNVTAYYRTCLFRLCQSGGNESELCDSVARYASACKNADVEVGPWRTYDFCPLECPENSHFEECIT-CTETCETLTLG-PICVDSCSEGCQCDEGYALLGSQCVTRSECGCNFEGHQLATNETFWVDLDCQIFCYCSGTDNRVHCETIPCKDDEYCMEEGGLYYCQARTDASCIVSGYGHYLTFDGFPFDFQTSCPLILCTTGS--------------RPSSDSFPKFVVTAKNEDRDPSLALWVKQVDVTVFGYSIVIHRAYKHTVLVNSERLYLPLKLGQGKINIFSFGFHVVVETDFGLKVVYDWKTFLSITVPRSMQNSTYGLCGRYNGNPDDDLEMPMGLLASSVNEFGQSWVKRDTFCQVGCGDRCPSCAKVEG--------------------------------------FSKVQQLCSLIPNQNAAFSKCHSKVNPTFFYKNCLFDSCIDGGAVQTACSWLQNYASTCQTQGITVTGWRNYTSCTVTCPPNSHYESCVSVCQPRCAAIRLKSDCSHYCVEGCHCDAGYVLNGKSCILPHSCGCYSDGKYYEPKQLFWNSDCTRRCRCFRRNVIQCDPRQCKSDEECALRNGVRGCFSTKTSYCLAAGGGVFRTFDGAFLRFPANCAFVLSTICQKLPDISFQLIINFDKWSAPNLTIISPVYFYINEEQILINDRNTVKVNGTQVNVPFITGLATKIYSSEGFLVIDTSPDIQIYYNGFNVIKISISERLQNKVCGLCGNFNGDLTDDYVTLRGKPVVSSVVLAQSWKTNGMQKRPLAPSCNELQFSQYAAMCDNVHIQKMQGDGYCLKLTDMKGFFQPCYGLLDPLPFYESCYLDGCYSHKKFQLCGSLAAYGEACRSFGILSTEWIEKENCSGVVEDPCVGADCPNRTCELGNGRELCGCIEPPPYGNNSHDIIDAEVTCKAAQMEVSISKCKLFQLGFEREGVRINDRQCTGIEGEDFISFQINNTKGNCGNIVQSNGTHIMYKNTLWIESANNTGNIITRDRTINVEFSCAYELDIKISLDSVVKPMLSVINLTVPTQEGSFITKMALYKNASYKHPYRQGEVVLTTRDVLYVGVFVVGADATHLILTLNKCYATPTRDSNDKLRYFIIEGGCQNLKDNTIGIEENAVSLTCRFHVTVFKFIGDYDEVHLHCAVSLCDSEKYSCKITCPHNSRIATDYTKEPKEQIISVGPIRRKRLDWCEDN-GGCEQICTSRVDGPLCSCVTGTLQEDGKSCRASNSSMELQVWTLLLIMIQISLWHFVYKSGTTS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ASW3-1", "uniprot_id": "A0A8M3ASW3_DANRE", "id": "A0A8M3ASW3-1", "name": "", "aln": "MVRTGTLVSLLQLFSTLVPSGAFSQDTLYPFGPAHRDLETPKMDDGSSPEIPLLIPFIFFNVPYRSLYVNNNGVISFNIQVSQFTPEAFPLSDSRSFIAPLWADVHNGIRGDVYYRESTDTEILERATQDVRKYFKNMVSFTATWVFITTWNQVTFYGGSQTTPVNTFQAVLISDGHAYFSMFNYGEIHWSTGTASGGDPLTGLGGTTAQAGFNGGDVSHFFNLPGSRSNEVVNIEQTTNVNVPGRWFFRIDADQIDPANGCSYIGRFYRRGEVFWLSDQCTQRCRCLDLDNEVICHETPCGQLETCEQVEGAYYCQPTRTSTCVVFGDPHYHTFDGFLYHFQGTCSYLLARPCWEMPGLPFFSVEAKNENRGVPTVSWLRDVTVEVYNHRVTLPKGTLGTVQVDGLIKTLPVQLQLGAVKVYQSGVAVALETDFGLLVTYDGLHYASISLPSSYFNNTCGLCGNYNDDPADDPVLPDGSLAESVVELGGSWRAEDTDFRCTDGCAQNCSMCEPAAEAFYFRSDYCGLINKTDGPFRDCRAVVDPTAFVYSCVYDMCSNRDNITTLCQAIQAYALACQALGVTIRPWRSRS--FCALTCPENSHYQVCTSACPASCSDLTSHLYCAHPCTEGCQCDQGYVLSGSRCVRRFECGCERDGLYYALNETFWAGEGGEVGEDCSQRCVCGPAGEVKCFNDSCGEGEVCAAEVGLLGCYPRREAICSLSQSQILATFDGSTMPFPDESSFYLVKTLGRLPANVTSVEVKIGRKLVNKGPTWLRPVVVRVGHLEAQIGGSDFDLIKVNGEPAIVPYVHPVEPLMIYRSSGNTTVIEWSGLVRTRYSRQGLLNITLSTLFYNTTCGLCGFFNGDPIDDLRLPSGRQADSADQFIESWRAIADDLTCNGDCEDLYRMCTD----LRQYQSPWLCGNINDPGNSSFLACHTAVNPSPFFRNCLYNMCVREGNRSALCNSLQAYASACQDAQINLGTWRSATNCPLPCPENSHFDECTSACPLTCSNLDEPEEPCPLPCSEGCQCEEGFALRDGICVARSDCGCFYLGRQLATNETFWTDWECQERCFCNGTDNSVYCTFSPCHPEEYCQENEGLFFCQPRTEAMCAVAGYAHFLPFGGVPFDLQSSCTLRLATTDCGEGDEDSFGGLDSAETVLGGLPNFQLSVRNEERDTGQAIWVRGFVLEVYGYEIEVSRSFKHTVTVNKERLYLPLKLGPGKVNIYTLGLQLLVETDFGLKVAFDWNTLLLLTLPRSLFNATCGLCQG----------LPISGPALSVTEWGMAWADRDTFCQVGCGDSCPRCGLVERGLAAEVPAQVTDAVGNIDMDNGNPGNRFHFAEGLYVYVEPEAVRLCGLIIDRGGVFARCHSKVAPAYFYQSCLQDTCVDQGARETICNWLQIYASTCQTQGVPLIGWRSSTPCVWSCPVNSHYSSCMMACQPQCAPARGQRDCNQYCVEGCQCDQGYVLNGKSCILNQNCGCYTDGKYYEPKQLFWNSDCTKRCQCIGRNLIQCDPRRCKAEEECVLRHGVRGCFARRNQHCVASGGGVFRTFDGASLRLPASCSFVLSTICHKLPELSFQLIANFDKWSTPNLTTISHAYLYINEENILISG-NTVKVNGTPVSVPFVTGLMTRVSTSEGFLVIDTPQDIQVRYNRFNTLSITMGPRLQNKVCGLCGNFNGDPTDDYITSRGKPAVSALELAQSWKTNGMQN-----SCDETQYVALAQSCDNTAVSELQGEDNCLKLTDLKGFFQPCHGLLDPHPFYQSCYMDGCYNHRKAQVCGSMAAYAEACRSFGTLTTKWITQENCSEWIYDPCAGEICSNNTCEQENG-ELCGCPELPNNDISEDDIIQAEVTCKHAQMEVSISKCRLFQLGFEREDVRINDQHCPGIEGEDFISFHINNTKGHCGSIVQSNGTHIMYKNTVWIESLNNTGSVVTRDKMINVEFSCAYELDIKISLETVLKPMLSVINLTLPTQEGNFITKMALYKNASYRHPYREGEVVLSTRDVLFVGVFVEGADDKQLILIVNMCWATPSRYSNDRLRYIIIERGCPNIKDNTIGMAENGVSLTCRFHVTVFKFIGDYDEVHLHCDVTLCDSETNACKVNCPHNKRSYTDYS-QHKEQILSVGPIRRRDSDWCEENNGGCEQICTSQVTGAVCSCVTGMLQRDGKSCRVTSMSTDLQP--LLLLAAAVVSVNIVLQTHTSVFFS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :. * :.:: :** * .:: :*** :.* .***:*****.** * **.:**.****::*******:***: *******:***:*.*:*:**:**********::****: :. **.***:*:*****:*.:*:******.**::*******.***********:*** *::*** **:*:***************. ********::::**.*****: *:***::********** *::*..:*******: *:* ******* . :** :*****::**: *:*:.*. *.** :**....********:**********:****:*:***** * : ..***********:* .:***:::::*** .::: :***: * *:*:.*:.:*** *:**:**:****::.*:*********:** ******:*.**:*.*********.:* ** : *** * **::** ***. .:*::* .** :**: *:.*:**:** *****::******: :* :***.****:*****:** *** * **********.*****:.* ** :: ..:: **. ***.****:** :*****: ** ******:*::*:*** *:** .:***: :* **::.* *** . *: :*:* .*:* ***.:* .*****.* * **:*:**::* ***.*:* ****:: .**.* *: *:** . * :*:.*.:: : **:*** : : *.. *.:*** . :*:**: . :*:.** * *:*.. *:*.:* .*:* .:** *** * *** ::* * *****:*.:. *:: **.*: :*. *:*** :: : ***:* ** : *.: *: *:* ** ****.***** ** .** :.::*.**:.:* **.* **:*: *****::*::::*.**: *** *******:** : *. **..* * .*******:**:** .. **.**:*** : *:*********.* :** *:*.**** *:* **: ::** *: **::**.**:* * *:**.*:*.*.* ***:*:**.* *.**.. .. ..:*:* ::.:**:**.. *:**: . : *:**.* : *::**** **.********** **:**:::*::::*********.:**:*:* :*:***: *.* *** :*:. * *:.*:* :*..*********** ** *. ** .:. :**.** ::.. *::***** *::**:.** *:*:* ** :* *.*** *********:.: ***. *.* :** ****.**: .***:**. * : **.:******:** *********** :.****:*************.***:**:*: **:******:**::***.** ******: :..:*:*:*********** **:**.*:*******:***::***** ******:**** ** .*:*****:***.. ******** *.***:*** *:: :*********. ***: ** **.:.*::. **************** ****:* ****.**:: ***********: **:* *: * ***. :. :**:. ******:*******:***** ***:***:****.*:* *:***:***.******* *:*:** :**** : ***.* *.*.*** ** ***** * * . ...***:****** **********:*********.*****::*.**********:******:**.:*************:**** ****.::***: *****************::*:**********:*****.* ***********:****:*****:*****:***** *** .:*** :* *:***:* ***:***:*** ** *:******: **.************************* *:*****. :**:.**:*.* ***: : ****:*******: ****:* *****:***:* *.:****** **.**:***.:. * : * ***: : ::: :: :: ", "identical_positions": 1287, "similar_positions": 534, "identity": "57.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-126", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96AA3-1", "uniprot_id": "RFT1_HUMAN", "id": "Q96AA3-1", "name": "Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1", "aln": "MGSQEVLGHAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGVVNVRLTLLYSTTLFLAREAFRRACLSG-GTQRDWSQTLNLLWLTVPLGVFWSLFLGWIWLQLLEVPDPNVVPHYATGVVLFGLSAVVELLGEPFWVLAQAHMFVKLKVIAESLSVILKSVLTAFLVLWLPHWGLYIFSLAQLFYTTVLVLCYVIYFTKLLGSPESTKLQTLPVSRITDLLPNITRNGAFINWKEAKLTWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIVNNLGSLVARLIFQPIEESFYIFFAKVLERGKDATLQKQEDVAVAAAVLESLLKLALLAGLTITVFGFAYSQLALDIYGGTMLSSGSGPVLLRSYCLYVLLLAINGVTECFTFAAMSKEEVDRYNFVMLALSSSFLVLSYLLTRWCGSVGFILANCFNMGIRITQSLCFIHRYYRRSPHRPLAGLHLSPVLLGTFALSGGVTAVSEVFLCCEQGWPARLAHIAVGAFCLGATLGTAFLTETKLIHFLRTQLGVPRRTDKMT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C3B8-1", "uniprot_id": "RFT1_MOUSE", "id": "Q8C3B8-1", "name": "Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1", "aln": "MGSQEVLGQAARLASSGLLLQVLFRLITFVLNAFILRFLSKEIVGIVNVRLTLLYSTTTFLAREAFRRACLSG-GAQRDWSQTLNLLWLTVPLGIFWSSCLGWVWLQLLEVPDPDVVPYYGTGVLFFGLSAVVELLGEPFWVLAQAHMFVKLKVLAESMSVILRSVLTALLVLWLPHWGLYIFSLAQLLYTTVLVLCYAIYLIQLLRSPESAKQLTLPVSRVTQLLPSISRSRAFVNWKEAGLAWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIVNNLGSLVARLIFQPVEESFYLFFAKVLEREKDASLQKQDDVAVAAAVLESLLKLALLTGLTMTVFGFAYSQLALDIYGGAMLSSGSGPVLMRCYCLYVLLLAINGVTECFMFAAMSKEEVDRYNFTMLALSSSFLVLSYLLTSWCGSVGFIMANCFNMGIRITQSLSFIHHYFRESPHRPLAGLRLSPVLLGVFILSAGITSVSEAFLCCERGWPARLAHIAVGTICLGVTLGTAFLTETKLIHFLRTQLGRSRLSDKMT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7EXE6-1", "uniprot_id": "E7EXE6_DANRE", "id": "E7EXE6-1", "name": "Protein RFT1 homolog", "aln": "MGSEDVLKSASTLASYNVLLQVMFRVLTFLLNAFTLRFVSKELIGVVNVRLMLLYSTLVFLSREAFRRACLSGEGAGRNWRQVINLLWLTFPLGCVWGVLLVCVWWWVLQAPDPDSIPHYVPAVGLFCVAALTELLAEPLWVLAHAHMFVRLKVIAESLAMIAKCLVTVVLVVSAPQWGLFIFSAAQCVYTGFLLTCYVVYFIHFLGS-EEAEKKSFPVYRMTDLLPSKVDHEPLLNWKLTTLTWSFFKQSFLKQILTEGERYVMTFLNVLNFGDQGVYDIINNLGSMVARFLFLPIEESFYVFFAKVLERGRDVQHQKQEEVSMAAEVLECLLKLVLLIGLIITVFGYAYSHLALDIYGGELLSNGAGPALLRCYSCYVLLLAINGVTECFVFAAMSKEEVDRYNLVMLGLSASFLLLSYWLTWMFGGVGFILANCCNMALRITHSIVYIRQYFLQSEHRPLWGLRPHSAVLVALGVSAVITAFSESVFCCDGGWLLRLFHVAVGAVCLLTVVITVFLTETRLVQFVKTQL-LPKYNKKLT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***::** *: *** .:****:**::**:**** ***:***::*:***** ***** **:*********** *: *:* *.:******.*** .*. * :* :*:.***: :*:* ..* :* ::*:.***.**:****:*****:***:***:::* :.::*..**: *:***:*** ** .** .*: **.:*: ::* * *.:: ::** *:*:***. .::*** : *:*************************************:*****:***::* *:*****:******** :*. ***::*::** ***.****.** ** :****:***:******** :**.*:**.*:*.*. ************** *************:.**.**:***:*** ** *.****:*** **.:***:*: :*::*: .* **** **: ..:* .: :*. :*:.** .:**: ** ** *:***:.** ..: *.*****:*::*::*** .: ..*:*", "identical_positions": 322, "similar_positions": 144, "identity": "59.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-13", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V656-1", "uniprot_id": "G3V656_RAT", "id": "G3V656-1", "name": "RNA methyltransferase", "aln": "--------------------------------------------------------------------------------------MIEMAAEKEPFLVPAPPPPLKDESGGGGGPEVRSHQEAASGELLDGTERGPGPRAHSAG--ATASG--------------------GGGPQAQTHGEPHG----RAAAPADVGEERRGGGGTDLGPPAPPRPRNGYQPHRPPVGGGGKRRNSCNVGGGSGGSFKHPAF-KRRRRVNSDCDS----------------------------------------VLPSNFLLGGNIFDPLNLNSLLDEEVSRALNAETPKSS---PLPAKGRDPVEILIPKDITDPLSLN-----------------TCTDEAHVVLASPLKIGRKRHRHRGPHHQQQQ-ASGGNDS-QAVLPTDPLTPSVHG----------------------------------------------------------------------------------------------------------------EGAT--QQHRGQNRDDPQPYELNTAINCRDEVVSP------------------------------LPSALQGSSGSLSAPPAASVTSAPS-SSSSRHRKRRRTSSKSE--------AGARGGSQGSKEKGRGSGGGR--HHHPLPATGFKKQQL---------------------------------------------------------------------------KFQYGNYCKYYGYRNPS---CED-MRLRVLKPEWFQGRDVLDLGCNVGHLTLSIACKWGPARMVGLDIDPRLIHSARQNIRHYLSEEL---------------------------RLQAQTSEGDPGTEGEEGTTTVRKRS-------------------------CFPASLTASRGPIAAPHLPLDGADTSVFPNNVVFVTGNYVLDRDELVDAQRPEYDVVLCFSLTKWVHLNWGDEGLKRMFRRIYRHLRPGGILVLEPQPWSSYCRRKSLTETIYKNYFRIQLKPEQFSSYLTSPEASSVRCTCSTRPDLPATEWLSELEVVKRLPLLLLRTWKKRKLSQGLS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K3A9-1", "uniprot_id": "MEPCE_MOUSE", "id": "Q8K3A9-1", "name": "7SK snRNA methylphosphate capping enzyme", "aln": "--------------------------------------------------------------------------------------MIEMAAEKEPFLVPAPPPPLKDESGGGGGPEVQSHQEAASGELRDGTEHGPGPRAHSAG--AAASG--------------------GGGPQAQAHGEPHG----RAAAPADVGEERRGGGGTDLGPPAPPRPRNGYQPHRPPGGGGGKRRNSCNVGGGSGGSFKHPAF-KRRRRVNSDCDS----------------------------------------VLPSNFLLGGNIFDPLNLNSLLDEEVSRALNAETPKSS---PLPAKGRDPVEILIPKDITDPLSLN-----------------TCTDEAHVVLASPLKIGRKRHRHRGPHHQQQQQASGGNDSNAAVLPTDPLTPSLHG----------------------------------------------------------------------------------------------------------------EGATQQQQNRGQNRDAPQPYELNTAINCRDEVVSP------------------------------LPSALQGSSGSLSAPPAASVTSAPSTSSSSRHRKRRRTSSKSE--------AGARGGSQGSKEKGRGSGGGRH-HHHPLPATGFKKQQL---------------------------------------------------------------------------KFQYGNYCKYYGYRNPS---CED-VRLRVLKPEWFQGRDVLDLGCNVGHLTLSIACKWGPARMVGLDIDPRLIHSARQNIRHYLSEEL---------------------------RLQAQTSEGDPGTEGEEGTITVRKRS-------------------------CFPASLTASRGPIAAPQVPLDGADTSVFPNNVVFVTGNYVLDRDELVDAQRPEYDVVLCFSLTKWVHLNWGDEGLKRMFRRIYRHLRPGGILVLEPQPWSSYCKRKSLTETIYKNYFRIQLKPEQFSSYLTSPEVG------FSSYELVATPNNTSRGFQR--PVYLFH--KARSPSH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7L2J0-1", "uniprot_id": "MEPCE_HUMAN", "id": "Q7L2J0-1", "name": "7SK snRNA methylphosphate capping enzyme", "aln": "--------------------------------------------------------------------------------------MIEMAAEKEPFLVPAPPPPLKDESGGGGGPTVPPHQEAASGELRGGTERGPGRCAPSAGSPAAAVGRESPGAAATSSSGPQAQQHRGGGPQAQSHGEARLSDPPGRAAPPDVGEERRGGGGTELGPPAPPRPRNGYQPHRPPGGGGGKRRNSCNVGGG-GGGFKHPAF-KRRRRVNSDCDS----------------------------------------VLPSNFLLGGNIFDPLNLNSLLDEEVSRTLNAETPKSS---PLPAKGRDPVEILIPKDITDPLSLN-----------------TCTDEGHVVLASPLKTGRKRHRHRGQHHQQQQ-AAGGSES-HPVPPTAPLTPLLHG----------------------------------------------------------------------------------------------------------------EGASQQPRHRGQNRDAPQPYELNTAINCRDEVVSP------------------------------LPSALQGPSGSLSAPPAASVISAPP-SSSSRHRKRRRTSSKSE--------AGARGGGQGSKEKGRGSWGGRHHHHHPLPAAGFKKQQR---------------------------------------------------------------------------KFQYGNYCKYYGYRNPS---CED-GRLRVLKPEWFRGRDVLDLGCNVGHLTLSIACKWGPSRMVGLDIDSRLIHSARQNIRHYLSEEL---------------------------RLPPQTLEGDPGAEGEEGTTTVRKRS-------------------------CFPASLTASRGPIAAPQVPLDGADTSVFPNNVVFVTGNYVLDRDDLVEAQTPEYDVVLCLSLTKWVHLNWGDEGLKRMFRRIYRHLRPGGILVLEPQPWSSYGKRKTLTETIYKNYYRIQLKPEQFSSYLTSPDVG------FSSYELVATPHNTSKGFQR--PVYLFH--KARSPSH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6H6-1", "uniprot_id": "A0ACD6B6H6_DANRE", "id": "A0ACD6B6H6-1", "name": "RNA methyltransferase", "aln": "-----------------------------------------------------------------------------------------MSTVMS---VQSELP----IAGGAAG--LLAHPPSPLQTIKDEVTANIVLTELAAN-----------------------------------HVTPQD------GVTAEGPFQIKNG----------LQTRTEVQTQKLAQ----KRRYSMNV------AFKHPSLGKRRRRANSECDP----------------------------------------VLPTNFLLGGNIFDPLNLNSLLDEEVSKALNAETPKSS---PLPSKNRDPVEILIPKDITDPLNLSG----------------RGGDSAAGVLVSPMKIRR-RHRNR-HHPGATTGVADQSDCEKSKTNETTLFPVANP----------------------------------------------------------------------------------------------------------------EEAAN-SAVLPPVEESPRPYELNTSINCRDEVVQPI-----------------------------LPRRKSHPSASSSAPQLLSRSASAP--HPSKHRKRRRTVSRSDSRLSITPTPPTKRLITHTQTFHTPVIGGAS-GAPPLGAERSHEQQRRP-----------------------------------------------------------------------RRKYHNGAYSRYYGYRTPS---MTDDPRLALFNPEWFSGKKVLDVGCNTGHVTLAIAKHCSPAHILGLDIDGALVQAARQNLRHFLSELQD--------------------------RQQAGAGEGSEVTGLVPLMDLQLVLP-------------------------RFPVSFMRCRGPIAAP--PIMHQSPGQFPSNVCFLKGDYVPDSDAAVVSQSAEYDVILCLSLTKWVHLNYGDAGIQRLFGRIYRHLLPGGVLILEPQPWSSYSRHKRLTDVTRRNYSSIRLKPDKFSSFLMA-EVG------FSSYELIGTPRASPKGLQR--SVYLFH--KSPASSRK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VNH1-1", "uniprot_id": "BN3D2_DROME", "id": "Q9VNH1-1", "name": "U6 snRNA methylphosphate capping enzyme Amus", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDLENNNNTPLTGKQAEKCAKK------------------------------------RKCVITLDEKQVESKRLKKEESNVEATS----------RPP----------------------------AQSPKKRLHLNGKPMQNKD---------------------------------------------------------------------------LNFKYGNYKHYYGKRILNKDFHDIRLDVLGTQPDLFRNKQLLDIGCNSGHLSIQIARKFEVKSLVGLDIDRGLIN-----------------------------------------DAQKTVSHLKRHATPGQGIPH-------------------------------------------------------------IQFVHGNYVLEDDVLLEIERPQFDVILCLSVTKWIHLNFCDSGLKQAFRRMYLQLRPGGKLILEPQSFDGYKRRKKLSEQIRDNYNAIKFRPDHFTEYLLSPEVG------FAEMKLMGIPEHCKVGFKRPIQIFTKS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7K480-1", "uniprot_id": "MEPCE_DROME", "id": "Q7K480-1", "name": "7SK snRNA methylphosphate capping enzyme bin3", "aln": "MEKRLSDSPGDCRVTRSTMTPTLRLDQTSRQEPLPQQPDNGPAAAPGKSKSPTPLPGKSQAAQHHQFRAPQQQQGPKNRNKAWSKRQHKAGGKHNPSACVGASSGQAQSTGSSVIAATLLPTAASAHKADLENIQNIHNKNLTAGGGVNHHG--NAGTAHHGGGGGAGAHHAAAGGHHHHHNTRLAQNAAAGGASGGGTIQMHKKMLRGHHHHVLCAGNNANHTCCLVTGCNGSSIGGVGVAGSGGATASAGGGGASCKEAQSCKDTSSLSGNSSIAGSAGAGNAVHYCCGRSKFFLPEKRLRKEVIVPPTKFLLGGNISDPLNLNSLQNENTSNASSTNNTPATTPRQSPITTPPKVEVIIPPNIHDPLHLLDPVDSMEYEKQLTSPMKRAGPGGGMLHHRQHHYRTRKNRKRRRFDSNNTSHAGDEGGVGSELTDEPPLPAATSSLAASPVAAPLNVGGSLLLSESAAPAPGETAEMGQQQEQAHVHSPQSASTTTTAAEMPTPTPTSAAAATATAEHKEQSAPAPTATSSPQRQQQHVAAAAEELPTPETSAAAETPAEEMLLSCSATSASLVASTLAERRASRDLRLDLSSTCYGVGGTGLSFGGSISSSVGSSFGGGGRKRKISESSTSQKSKKFHRHDAMDKIVSPVVPQPGAWKRPPRILQPSGARKPSTRRSTSVSESELLSPVEEQPPKQLPLIGVEIPRDDTPDLPDHGLGSPLSTTSGATSHTAGEQDSLAGVDISMGDTLGSGVVGKAPLTSSLMLEPAKIPPIKMLPKFRADGLKYRYGNFDRYVDFRQMN-EFRDVRLQVFQRHVELFENKDILDIGCNVGHMTITVARHLAPKTIVGIDIDRELVARARRNLSIFVRIPKEEKLLEVKAEPTVDAKANIAVKDETSGAAHKKTRRGKRRRKVHQGIHHHHHHHHDLEQLQQQQKLNSLLVKPHEFFPISFPLTYGRIPRILSSSKSPNMLGNKNQFPANVFFRHTNYVLKDESLMASDTQQYDLILCLSVTKWIHLNFGDNGLKMAFKRMFNQLRPGGKLILEAQNWASYKKKKNLTPEIYNNYKQIEFFPNKFHEYLLSSEVG------FSHSYTLGVPRHMNKGFCRPIQLYAKGDYTPNHVRWSDAYYPQTPYEAYRGIYATLPVHRMGGGGSSAGGSNSGHAQMLHLSSSSRSQNYDTPHYAGSASGSASCRQTPMYQPTYNPLETDSYQPSYDMEYLNHMYVFASPLYQTVWSPPASLRKSSSHTPVFGSVRDAELDGDGSGGGGSGGGSYHRHVYPPNDDTCSPNANACNAFNSIRDADTDDSNQLPGGSRRHVYATNCGESSSSPQVNHHDAVGEFVDGLMDDEQKSSTGGGTGGAAYCDLSDA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . .: : . * . ..: ::: * : :* . * . : : : * .:.:**:*** **::: :* : ::*:*** *: . . . : * :** . : : : ::*::**:*:***:***: * *:: * *:: :* *** *:**.* : .* ::* *: ** *.: *::* .:* : :.. : . . : : ", "identical_positions": 52, "similar_positions": 80, "identity": "3.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-133", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZSE6-1", "uniprot_id": "D3ZSE6_RAT", "id": "D3ZSE6-1", "name": "", "aln": "MFAAATKSFVKQVGDGGRLIPVPSLSEADKYQPLSLVVKKKRCFLFPRCKFTSTPFTLKDILLGDRDISAGISSYQLLNYEDESDVSLYGRRSNHIVNDVGINVTGSDCIAVKASFGVVTKHEVEISTLLKEITARKINFDHSLIRQSRSSRKAVLCVVMESIRTTRQCSLSVHAGIRGEAMRFHFMDEQNPKGREKAIVFPAHTTIAFSVFELFIYLDGAFDICVTSVSKGGFE----REETTTFAMFY---RLRNIL--------FERNRRVMDAISRSQLYLDDLFSDFYDKPLSMTDIS---LKEGTHIRVNLLNHNIPKGPCILCGMGNLKRETVYGCFQCSVDGVKYVRLHAVPCFDIWHKRMK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0ZLH2-1", "uniprot_id": "PJVK_MOUSE", "id": "Q0ZLH2-1", "name": "Pejvakin", "aln": "MFAAATKSFVKQVGDGGRLVPVPSLSEADKYQPLSLVVKKKRCFLFPRCKFTSTPFTLKDILLGDREISAGISSYQLLNYEDESDVSLYGRRSNHIVNDVGINVTGSDSIAVKASFGVVTKHEVEVSTLLKEITARKINFDHSLIRQSRSSRKAVLCVVMESIRTTRQCSLSVHAGIRGEAMRFHFMDEQNPKGREKAIVFPAHTTIAFSVFELFIYLDGAFDICVTSVSKGGFE----REETTTFAMFY---RLRNIL--------FERNRRVMDAISRSQLYLDDLFSDFYDKPLSMTDIS---LKEGTHIRVNLLNHNIPKGPCILCGMGNLKRETVYGCFQCSVDGVKYVRLHAVPCFDIWHKRMK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q0ZLH3-1", "uniprot_id": "PJVK_HUMAN", "id": "Q0ZLH3-1", "name": "Pejvakin", "aln": "MFAAATKSFVKQVGDGGRLVPVPSLSEADKYQPLSLVVKKKRCFLFPRYKFTSTPFTLKDILLGDREISAGISSYQLLNYEDESDVSLYGRRGNHIVNDVGINVAGSDSIAVKASFGIVTKHEVEVSTLLKEITTRKINFDHSLIRQSRSSRKAVLCVVMESIRTTRQCSLSVHAGIRGEAMRFHFMDEQNPKGRDKAIVFPAHTTIAFSVFELFIYLDGAFDLCVTSVSKGGFE----REETATFALLY---RLRNIL--------FERNRRVMDVISRSQLYLDDLFSDYYDKPLSMTDIS---LKEGTHIRVNLLNHNIPKGPCILCGMGNFKRETVYGCFQCSVDGQKYVRLHAVPCFDIWHKRMK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QAQ7-1", "uniprot_id": "A0A8M9QAQ7_DANRE", "id": "A0A8M9QAQ7-1", "name": "", "aln": "MFAAATKNFVKQVGDTGRLVPVPSLSEADRYQPLSLVTRKKKRHFWKKTKYATTPFSLKDILVGEKEITAGVSSYQLLNYEDKSDVALNGRLGNHLIHEVGVNVSGSDSVAVKASFGIVTKHEVEVPTLLRELNARKVDLDHCLIRQSKESGRTVLCVVMESIRTTRQCSLTVHAGVRGTTMRFQIDDGRNPKGRDKAIVIPAHTTIAFSVLELYVRLDGRLDICVAPESMGGFEKEQIREQLGGFIGRFSVGRLRRFLSGIIYGNPFRADDRTFEELTHSDMYMDDVVTDYYEKAASMTDLSSAYLRDEKHTRVNLLNHNIPKGPCALCGMGHQRRETVYGCLECTSGGNKYVRLHAVPCFDLWHKTLR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*******.******* ***:*********:*******.:**: .:: : *:::***:*****:*:::*:**:**********:***:* ** .**::::**:**:***.:*******:*******:.***:*:.:**:::**.*****:.* ::*****************:****:** :***:: * :*****:****:**********:**:: *** :*:**:. * **** **: * : ***.:* *. : *.:: :::*::*:**:.:*:*:*. ****:* *:: .* ************** *****: :*******::*: .* ************:*** ::", "identical_positions": 226, "similar_positions": 95, "identity": "61.08%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-139", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99P67-1", "uniprot_id": "SOST_RAT", "id": "Q99P67-1", "name": "Sclerostin", "aln": "MQLSLAPC------LACLLVHAAFVAVESQGWQAFKNDATEIIPGLREYPEPPQE---LENNQTMNRAENGGRPPHHPYDTKDVSEYSCRELHYTRFVTDGPCRSAKPVTELVCSGQCGPARLLPNAIGRVKWWRPNGPDFRCIPDRYRAQRVQLLCPGGAAPRSRKVRLVASCKCKRLTRFHNQSELKDFGPETARPQKGRKPRPRARGAKANQAELENAY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99P68-1", "uniprot_id": "SOST_MOUSE", "id": "Q99P68-1", "name": "Sclerostin", "aln": "MQPSLAPC------LICLLVHAAFCAVEGQGWQAFRNDATEVIPGLGEYPEPPP-----ENNQTMNRAENGGRPPHHPYDAKDVSEYSCRELHYTRFLTDGPCRSAKPVTELVCSGQCGPARLLPNAIGRVKWWRPNGPDFRCIPDRYRAQRVQLLCPGGAAPRSRKVRLVASCKCKRLTRFHNQSELKDFGPETARPQKGRKPRPGARGAKANQAELENAY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQB4-1", "uniprot_id": "SOST_HUMAN", "id": "Q9BQB4-1", "name": "Sclerostin", "aln": "MQLPLALC------LVCLLVHTAFRVVEGQGWQAFKNDATEIIPELGEYPEPPPE---LENNKTMNRAENGGRPPHHPFETKDVSEYSCRELHFTRYVTDGPCRSAKPVTELVCSGQCGPARLLPNAIGRGKWWRPSGPDFRCIPDRYRAQRVQLLCPGGEAPRARKVRLVASCKCKRLTRFHNQSELKDFGTEAARPQKGRKPRPRARSAKANQAELENAY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PZF1-1", "uniprot_id": "A0A8M1PZF1_DANRE", "id": "A0A8M1PZF1-1", "name": "Sclerostin", "aln": "MQVSLALVHCGARLLLLLLLQGCFTAAHG--WRPLKNDATEIIPEYAEDTHKPEEQIQLSDNNTMNRAKNGGRRSSANTRTYGASELSCRELRSTRYVTDGSCRSVKPVKELVCSGQCLPAHLMPNSILRGKWWRSSSSDYRCIPAHSRTQRIQLQCPNGPN-RTYKIRVVTSCKCKRYTRQHNQSDVKES---SKKPRRNKKHRSKVPSINS------NSY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .** * **:: .* .... *:.::*****:** * .. * .:*:*****:**** . : ..** *****: **::***.***.***.******** **:*:**:* * ****....*:**** : *:**:** **.* *: *:*:*:****** ** ****::*: : :*::.:* *. . . :: *:*", "identical_positions": 100, "similar_positions": 60, "identity": "45.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-142", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q12912-1", "uniprot_id": "IRAG2_HUMAN", "id": "Q12912-1", "name": "Inositol 1,4,5-triphosphate receptor associated 2", "aln": "MESTPFSGVANQIHTLCERPTYGEVKDGALDVKRQHKCPGPTSGPSPGTNLSGCIRMNDDPSMEENGVERVCPESLLQSREYSSLPLPRHTSSTDGTITSSDPGLEILNMASCDLDRNSLCKKEEDTRSASPTIEAQGTSPAHDNIAFQDSTSKDKTILNLEAKEEPETIEEHKKEHASGDSVVSPLPVTTVKSVNLRQSENTSANEKEVEAEFLRLSLGFKCDWFTLEKRVKLEERSRDLAEENLKKEITNCLKLLESLTPLCEDDNQAQEIIKKLEKSIKFLSQCAARVASRAEMLGAINQESRVSKAVEVMIQHVENLKRMYAKEHAELEELKQVLLQN--ERSFNPLEDDDDCQIK-KRSASLNSKPSSLRR---VTIASLPRNIGNAGMVAGMENNDRFSRRSSSWRILGSKQ----SEHRPSLPRFISTYSWADAEEEKCELKTKDDSEPSGEETVERTRKPSLSEKKNNPSKWDVSSVYDTIASWATNLKSSIRKANKALWLSIAFIVLFAALMSFLTGQLFQKSVDAAPTQQEDSWTSLEHILWPFTRLRHNGPPPV---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TTY6-1", "uniprot_id": "A0AB32TTY6_DANRE", "id": "A0AB32TTY6-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------MRLCRYVKSGREQQVTVNLMACE--------------DQQVLSGNLAENSENDSEQGFRNEDQIDLEEPSVFDRLGPYSVDMT------EDELEAAFSRLSLAFRCDQYTLCQRLETEEHARDNAEDNLKLEVERGMEVLETLKGMCFDIKRAG-LLQRLELCLNIIGGTIGRISNTAEVLGAVHQEVKVSRAVELMVAHVENLNRRHEKNSFELEEMKKQMEKSNRERFFHEEKEETDAIVKPEKDLQKSHSQTQLRRRISTNVISKRQQVKESETLLSLVTSESSQRRESNPQKPDNTDDCLLMDRRQVLPREESPSQTTMVNISEIHSRPEPDPVNVKKNTSSHQRLRRKSALESSNVWLKRSEHYFRDCDRCVISLIQPQTHPQLTPFPQMRVLPADSTVRLYEDSLLKPAKSHWTVPNPLNLGGESKYIETFPVCICKPINVFKNK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: :. *. . *:: . . *: :*. : *:.*. .*: .: . .: .* . : . .: : *.*:** * ****.*:** :** :*:: **::** **:*** *: . :::**:*. :* * ::* ::::** .::::. .*::. **:***::** :**:***:*: *****:* : *: ****:*: : :. ** *: ::: *. :* ::. . . . :.*** ..: * ::: :: : .: ..: .**.*. : ...: ::* *** *. . : .: .: . :.: *. ::* .: * * :.. . *. * .. .. . :. : :. :: : : : ..*:: : . .. : . . .: : .*. : . ", "identical_positions": 94, "similar_positions": 172, "identity": "16.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-146", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1D3-1", "uniprot_id": "D4A1D3_RAT", "id": "D4A1D3-1", "name": "Sacsin", "aln": "MGTEETRWVR-VTVLRGCVGCRTVAVRATATGRDLKERIFAETGFPVAEQRLWRGDREIPDWIKIGDLT-SKTC-LFVNLQSKGLKGGGRFGQTTPPLVDFLKDILRRYPEGGQILKELIQNAEDAGATEVKFLYDETQYGTETLWSKDMAQYQGSALYVYNNAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPCIFSGDQIGMLDPHQTLFGPHESGQCWNLKDDIKEINELPDQFAPFIGVFGSTKETFTNGSFPGTFFRFPLRLQPSQLSSNLYTKQKVLELFDSFRADADTVLLFLKSVQAVSLHVREADGTEKLVFRVTASENKTLKHERPNSIKILGTAISNYCKKIPSNSVTCVTYHINIALEDESTKDAQKTSWLVCNSVGGRGISSKLDSLADELKFVPIIGLAMSLSGRD-EENGATSDFSGKAFCFLPLPPGEESRTGLPVHISGFFGLTDNRRSIKWRELDQWRDPAALWNQFLIVNVVPKAYATLILDSIKRLETEKSSDFPLSVDAIYKLWPEASKVKAHWHPVLGPLFSELFQHAVIYSVGGEWVKLEQVHFSELDESLESTQSVLNYLQRSGKQIARVPGNLAAAVQLSAASATSTASPVRKVTPVWVRQVLRKCAHLGSAEEKLHLLEFVLSDQAYSELLGLELLPLQSGAFVPFSSSVSDQDVVYITSEEFPRSLFPGLEARLILENLKPHLLAALKEAAQTRAQQLLWGYSGRPCTQLQLLNPERFARLIKEVMNTFWPGRELVVQWYPLSEDKHHPSISWLKMVWKNLYIHFSEDLTLFDEMPLIPRTPLDADQTCVELIRLRVPSVVILDDETEAQLPEFLADIVQKLGGIVLKRLDTSLQHPLVKKYIHSPLPSAILQIMEKIPLQKLCNQIASLLPTHKDALRKFLASLTDTSEKEKRIIQELTIFKRINHSSDQGISSYTKLKGCKVLDHTAKLPTELRLSVSVIDSSDEATIRLANMLKIEKLKTTSCLKFVLKDIENAFYTQEEVTRLMLWILENLSSLKNENPSVLDWLMPLKFIHMSQEHVVAASDLFDPDIEVLRDLFYNEEEACFPP-AVFTSPDILHSLRQIGLKNEASLKEKDVVQVAKKIEALQVSSCQNQDVLLKKAKTLLLVLNKNHTLLQSSEGKMALKKIKWVPACKERPPNYPGSLVWKGDLCNLCAPPDMCDAAHAVLVGSSLPLVESAHVSLEKTLGIFTKPTISAVLKHFKIVVDWYTSKTFSDEDYYQFQHILLEIYGFMHDHLSEGKDSFKALKYPWVWTGKNFCPLAQAVIKPIHDLDLQPYLYNVPKTMAKFHQLFKACGSIEELTSDHISMVIQKVYLKSDQELSEEESKQNLHLMLNIMRWLYSNQIPASPNTPVPIYHSKNPSKLVMKPIHECCYCDIKVDDLNDLLEDSVEPIILVHEDIPMKTAEWLKVPCLSTRLINPENMGFEQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSFMIDMRRNMDIRENLLDPGMAACHGPALWSFNNSEFSDSDFINITRLGESLKRGEVDKVGKFGLGFNSVYHITDIPIIMSREFMIMFDPNINHISKHIKDRSNPGIKINWSKQQKRLRKFPNQFKPFIDVFGCQLPLAVEAPYSYNGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLIIFTQSVNSMYLKYLKIEETNPTLAQDTIIIKKKACPSKALNAPVLSVLKEAAKLMKTCSSSNKKLPTDVPKSSCILQITVEEFHHVFRRIADLQSPLFRGPDDDPATLFEMAKSG-QSKKPSDELPQKTVDCTTWLICTCMDTGEALKFSLNESGRRLGLVPCGAVGVLLHETQEQKWTVKP---HIGEVFCYLPLRIKTGLPIHINGCFAVTSNRKEIWKTDTKGRWNTTFMRHVIVKAYLQALSVLRDLAISGELIDYTYYAVWPDPDVVHDDFSVICQGFYEDIAHGKGKDLTRVFSDGSMWVSMKNVRFLDDSILQRKDVGSAAFKIFLKYLKKTGSKNLCAVELPSSVKVGFEEAGCKQILLENTFSEKQFFSEVFFPNIQEIEAELRDPLMNFVLNEKLDEFSGILRVTPCVPCSLEGHPLVLPSRLIHPEGRVAKLFDIKDGRFPYGSTQDYLNPIILIKLVQLGMAKDDILWDDMLERAESVAEINKSDHAAACLRSSILLSLIDEKLKIRDPRAKDFAAKYQTIPFLPFLTKPAGFSLEWKGNSFKPETMFAATDLYTAEYQDIVCLLQPILNENSHSFRGCGSVSLAVKEFLGLLKKPTVDLVINQLKQVAKSVDDGITLYQENITNACYKYLHEAILQNEMAKATIIEKLKPFCFILVENVYVESEKVSFHLNFEAAPYLYQLPNKYKNNFRELFESVGVRQSFTVEDFALVLESIDQERGKKQITEENFQLCRRIISEGIWSLIREKRQEFCEKNYGKILLPDTNLLLLPAKSLCYNDCPWIKVKDSSVKYCHADIPREVAVKLGAIPKRHKALERYASNICFTAPGTEFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPALCVYNNQPFTEDDVRGIQNLGKGTKEGNPCKTGQYGIGFNSVYHITDCPSFISGNDILCIFDPHARYAPGATSVSPGRMFRDLDADFRTQFSDVLDLYLGNHFKLDNCTMFRFPLRNAEMAQVSEISSVPSSDRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKATGGLNVLYSVKGKITDGDRLKRKQFHASVIDSVTKKRQLKDIPVQQITYTMDTEDSEGNLTTWLICNRSGFSSMDKVSKSVISAHRNQDITLFPRGGVAACITHNYKKPHRAFCFLPLSLETGLPFHVNGHFALDSARRNLWRDDNGVGVRSDWNNSLMTALIAPAYVELLIQLKKRYFPGSDPTLSVLQNTPIHVVKDTLKKFLSFFPVNRLDLQPDLYCLVKALYSCIHEDMKRLLPVVRAPNIDGSDLHSAVIITWINMSTSNKTKPFFDNLLQDELQHLKNADYNITTRKTVAENVYRLKHLLLEIGFNLVYNCDETANLYHCLVDAAIPVSYVTPADVRSFLMTFSSPDTNCHIGKLPCRLQQTNLKLFHSLKLLVDYCFKDAEESEFEVEGLPLLITLDSVLQIFDGKRPKFLTTYHELIPSRKDLFMNTLYLKYSSVLLNCKVAKVFDISSFADLLSSVLPREYKTKNCAKWKDNFASESWLKNAWHFISESVSVTDDQEEPKPAFDVIVDILKDWALLPGTKFTVSASQLVVPEGDVLIPLSLMHIAVFPNAQSDKVFHALMKAGCIQLALNKICSKDSALVPLLSCHTANIDSPASILKAVHYMVQTSTFRTEKLVENDFEALLMYFNCNLSHLMSQDDLKILKSLPCYKSISGRYMSIAKFGTCYVLTKSIPSAEVEKWTQSSSSAFLEEKVHLKELYEVLGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRLASIEELSETKEQLFEKLESLLIIHDANNRLKQAKHFYDRTVRVFEVMLPEKLFIPKEFFKKLEQVIKPKNQVVFMTSWVEFLRNIGLKHVLSQQQLLQFAKEISVRANTENWSKETLQNTVDILLHHIFQERTDLLSGNFLKELSLIPFLCPERAPAEYIRFHPQYQEVNGTLPLIKFNGAQVNPKFKQCDVLQLLWTSCPILPEKATPLSIKEQEGSSLAPQEQLEQVLNMLNVNLDPPLDKVINNCRNICNITTLDEEMVKTRAKVLRSIYEFLSAEKREFRFQLRGVAFVMVEDGWKLLKPEEVVINLEYEADFKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKNSEGKQLDPNEMRTVKRVVSGLFKSLQNDSVKVRSDLENARDLALYLPSQDGRLVKSSILVFDDAPHYKSRIQGNIGVQMLVDLSQCYLGKDHGFHTKLIMLFPQKLRPRLLSSILEEQLDEETPKVCQFGALCSLQGRLQLLLSSEQFITGLIRIMKHENDNAFLANEEKAIRLCKALREGLKVSCFEKLQTTLRVKGFNPIPHSRSETFAFLKRFGNAVILLYIQHSDSKDINFLLALAMTLKSATDNLISDTSYLIAMLGCNDIYRISEKLDSLGVKYDSSEPSKLELPMPGTPIPAEIHYTLLMDPMNVFYPGEYVGYLVDAEGGDIYGSYQPTYTYAIIVQEVEREDADNASFLGKIYQIDIGYSEYKIVSSLDLYKFSRPDESSQSRDSAPTTPTSPTEFLTPGLRSIPPLFSGKESHKPASSKHHSPRKLKVNALPEILKEVTSVVEQAWKLPESERKKIIRRLYLKWHPDKNPENHDIANEVFKHLQNEINRLEKQAFLDQNADRASRRTFSTSASRFQSDKYSFQRFYTSWNQEATSHKSERQQQSKEKCPPSAGQTYSQRFFVPPTFKSVGNPVEARRWLRQARANFSAARNDLHKNANEWVCFKCYLSTKLALIAADYAVRGKSDKDVKPTALAQKIEEYSQQLEGLTNDVHTLEAYGVDSLKTRYPDLLPFPQIPNDRFTSEVAMRVMECTACIIIKLENFIQQKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLC8-1", "uniprot_id": "SACS_MOUSE", "id": "Q9JLC8-1", "name": "Sacsin", "aln": "METKFQRWVR-VTVLRGCVGCRTVAVPATATGRDLKERIFAETSFPVAEQRLWRGDREVPDWIKIGDLT-SKTCHLFVNLQSKGLKGGGRFGQTTPPLVDFLKDILRRYPEGGQILKELIQNAEDAGATEVKFLYDETQYGTETLWSKDMAQYQGSALYVYNNAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPCIFSGDQIGMLDPHQTLFGPHESGQCWNLKDDIKEINELPDQFAPFIGVFGSTKETFTNGSFPGTFFRFPLRLQPSQLSSNLYTKQKVLELFDSFRADADTVLLFLKSVQAVSLHVREADGTEKLVFRVTASENKALKHERPNSIKILGTAISNYCKKIPSNSVTCVTYHINIVLEDESTKDAQKTSWLVCNSVGGRGISSKLDSLADELKFVPIIGLAMPLSGKD-EENGAISDFSGKAFCFLPLPPGEESRTGLPVHISGFFGLTDNRRSIKWRELDQWRDPAALWNEYLIVNVVPKTYATLILDSIKRLETEKSSDFPLSVDTIYKLWPEASKVKAHWHPVLGPLFSELFQHAVIYSIGGEWVKLEQVHFSELDGSLESTRSVLNYLQSSGKQIAKVPGNLAAAVQLSAASATSSASPVRKVTPAWVRQVLRKCAHLGSAEEKLHLLEFVLSDQAYSELLGLELLPLQSGAFVPFSSSVSDQDVVYITSEEFPRSLFPGLEARLILENLKPHLLAALKEAAQTR---------GRPCTQLQLLNPERFARLIKEVMNTFWPGRELVVQWYPFSEDKRHPSLSWLKMVWKNLYIHFSEDLTLFDEMPLIPRTLLNEDQTCVELIRLRIPSVVILDDETEAQLPEFLADIVQKLGGIVLKRLDTSIQHPLVKKYIHSPLPSAILQIMEKIPLQKLCNQIASLLPTHKDALRKFLASLTDTSEKEKRIIQELTIFKRINHSSDQGISSYTKLKGCKVLDHTAKLPTDLRLSVSVIDSSDEATIRLANMLKIEKLKTTSCLKFVLKDIGNAFYTQEEVTQLMLWILENLSSLKNENSNVLDWLMPLKFIHMSQGHVVAAGDLFDPDIEVLRDLFYNEEEACFPP-TIFTSPDILHSLRQIGLKNESSLKEKDVVQVARKIEALQVSSCQNQDVLMKKAKTLLLVLNKNQTLLQSSEGKMALKKIKWVPACKERPPNYPGSLVWKGDLCNLCAPPDMCDAAHAVLVGSSLPLVESVHVNLEQALSIFTKPTINAVLKHFKTVVDWYTSKTFSDEDYYQFQHILLEIYGFMHDHLSEGKDSFKALKFPWVWTGKNFCPLAQAVIKPTHDLDLQPYLYNVPKTMAKFHQLFKACGSIEELTSDHISMVIQKVYLKSDQELSEEESKQNLHLMLNIMRWLYSNQIPASPNTPVPIYHSRNPSKLVMKPIHECCYCDIKVDDLNDLLEDSVEPIILVHEDIPMKTAEWLKVPCLSTRLINPENMGFEQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSFMIDMRRNMDIRENLLDPGMAACHGPALWSFNNSEFSDSDFLNITRLGESLKRGEVDKVGKFGLGFNSVYHITDIPIIMSREFMIMFDPNINHISKHIKDRSNPGIKINWSKQQKRLRKFPNQFKPFIDVFGCQLPLAVEAPYSYNGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLIIFTQSVNSMYLKYLKIEETNPSLAQDTIIIKKKVCPSKALNAPVLSVLKEAAKLMKTCSSSNKKLPTDVPKSSCILQITVEEFHHVFRRIADLQSPLFRGPDDDPATLFEMAKSG-QSKKPSDELPQKTVDCTTWLICTCMDTGEALKFSLNESGRRLGLVPCGAVGVLLHETQEQKWTVKP---HIGEVFCYLPLRIKTGLPIHINGCFAVTSNRKEIWKTDTKGRWNTTFMRHVIVKAYLQALSVLRDLAIGGELTDYTYYAVWPDPDLVHDDFSVICKGFYEDIAHGKGKELTRVFSDGSMWVSMKNVRFLDDSILQRKDVGSAAFKIFLKYLKKTGSKNLCAVELPSSVKAGFEEAGCKQILLENTFSEKQFFSEVFFPNIQEIEAELRDPLMNFVLNEKLDEFSGILRVTPCVPCSLEGHPLVLPSRLIHPEGRVAKLFDTKDGRFPYGSTQDYLNPIILIKLVQLGMAKDDILWDDMLERAESVAEINKSDHAAACLRSSILLSLIDEKLKIKDPRAKDFAAKYQTIPFLPFLTKPAGFSLEWKGNSFKPETMFAATDIYTAEYQDIVCLLQPILNENSHSFRGCGSVSLAVKEFLGLLKKPTVDLVINQLKQVAKSVDDGITLYQENITNACYKYLHEAVLQNEMAKATIIEKLKPFCFILVENVYVESEKVSFHLNFEAAPYLYQLPNKYKNNFRELFESVGVRQSFTVEDFALVLESIDQERGKKQITEENFQLCRRIISEGIWSLIREKRQEFCEKNYGKILLPDTNLLLLPAKSLCYNDCPWIKVKDSTVKYCHADIPREVAVKLGAIPKRHKALERYASNICFTALGTEFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPALCVYNNQPFTEDDVRGIQNLGKGTKEGNPCKTGHYGIGFNSVYHITDCPSFISGNDILGIFDPHARYAPGATSVSPGRMFRDLDADFRTQFSDVLDLYLGNHFKLDNCTMFRFPLRNAEMAQVSEISSVPSSDRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKATGGLNVLYSVKGKITDGDRLKRKQFHASVIDSVTKKRQLKDIPVQQITYTMDTEDSEGNLTTWLICNRSGFSSMEKVSKSVISAHKNQDITLFPRGGVAACITHNYKKPHRAFCFLPLSLETGLPFHVNGHFALDSARRNLWRDDNGVGVRSDWNNSLMTALIAPAYVELLIQLKKRYFPGSDPTLSVLQNTPIHVVKDTLKKFLSFFPVNRLDLQPDLYCLVKALYSCIHEDMKRLLPVVRAPNIDGSDLHSAVIITWINMSTSNKTRPFFDNLLQDELQHLKNADYNITTRKTVAENVYRLKHLLLEIGFNLVYNCDETANLYHCLVDADIPVSYVTPADVRSFLMTFSSPDTNCHIGKLPCRLQQTNLKLFHSLKLLVDYCFKDAEESEFEVEGLPLLITLDSVLQIFDGKRPKFLTTYHELIPSRKDLFMNTLYLKYSSVLLNCKVAKVFDISSFADLLSSVLPREYKTKNCAKWKDNFASESWLKNAWHFISESVSVTDDQEEPKPAFDVIVDILKDWALLPGTKFTVSTSQLVVPEGDVLIPLSLMHIAVFPNAQSDKVFHALMKAGCIQLALNKICSKDSALVPLLSCHTANIDSPASILKAVHYMVQTSTFRTEKLMENDFEALLMYFNCNLSHLMSQDDIKILKSLPCYKSISGRYMSIAKFGTCYVLTKSIPSAEVEKWTQSSSSAFLEEKVHLKELYEVLGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRLASIEEPSEIKEQLFEKLESLLIIHDANNRLKQAKHFYDRTVRVFEVMLPEKLFIPKEFFKKLEQVIKPKNQAAFMTSWVEFLRNIGLKYALSQQQLLQFAKEISVRANTENWSKETLQSTVDILLHHIFQERMDLLSGNFLKELSLIPFLCPERAPAEYIRFHPQYQEVNGTLPLIKFNGAQVNPKFKQCDVLQLLWTSCPILPEKATPLSIKEQEGSDLAPQEQLEQVLNMLNVNLDPPLDKVINNCRNICNITTLDEEMVKTRAKVLRSIYEFLSAEKREFRFQLRGVAFVMVEDGWKLLKPEEVVINLEYEADFKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKSSEGKQLDPNEMRTVKRVVSGLFKSLQNDSVKVRSDLENARDLALYLPSQDGKLVKSSILVFDDAPHYKSRIQGNIGVQMLVDLSQCYLGKDHGFHTKLIMLFPQKLRPRLLSSILEEQLDEETPKVCQFGALCSLQGRLQLLLSSEQFITGLIRIMKHENDNAFLANEEKAIRLCKALREGLKVSCFEKLQTTLRVKGFNPIPHSRSETFAFLKRFGNAVILLYIQHSDSKDINFLLALAMTLKSATDNLISDTSYLIAMLGCNDIYRISEKLDSLGVKYDSSEPSKLELPMPGTPIPAEIHYTLLMDPMNVFYPGEYVGYLVDAEGGDIYGSYQPTYTYAIIVQEVEREDADNTSFLGKIYQIDIGYSEYKIVSSLDLYKFSRPDESSQNRDSAPTTPTSPTEFLTPGLRSIPPLFSGKESHKSPSTKHHSPRKLKVNALPEILKEVTSVVEQAWKLPESERKKIIRRLYLKWHPDKNPENHDIANEVFKHLQNEINRLEKQAFLDQNADRASRRTFSTSASRFQSDKYSFQRFYTSWNQEATSHKSERQQQSKEKCPPSAGQTYSQRFFVPPTFKSVGNPVEARRWLRQARANFSAARNDLHKNANEWVCFKCYLSTKLALIAADYAVRGKSDKDVKPTALAQKIEEYSQQLEGLTNDVHTLEAYGVDSLKTRYPDLLPFPQIPNDRFTSEVAMRVMECTACIIIKLENFIQQKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZJ4-1", "uniprot_id": "SACS_HUMAN", "id": "Q9NZJ4-1", "name": "Sacsin", "aln": "METKENRWVP-VTVLPGCVGCRTVAALASWTVRDVKERIFAETGFPVSEQRLWRGGRELSDWIKIGDLT-SKNCHLFVNLQSKGLKGGGRFGQTTPPLVDFLKDILRRYPEGGQILKELIQNAEDAGATEVKFLYDETQYGTETLWSKDMAPYQGPALYVYNNAVFTPEDWHGIQEIARSRKKDDPLKVGRFGIGFNSVYHITDVPCIFSGDQIGMLDPHQTLFGPHESGQCWNLKDDSKEISELSDQFAPFVGIFGSTKETFINGNFPGTFFRFPLRLQPSQLSSNLYNKQKVLELFESFRADADTVLLFLKSVQDVSLYVREADGTEKLVFRVTSSESKALKHERPNSIKILGTAISNYCKKTPSNNITCVTYHVNIVLEEESTKDAQKTSWLVCNSVGGRGISSKLDSLADELKFVPIIGIAMPLSSRDDEAKGATSDFSGKAFCFLPLPPGEESSTGLPVHISGFFGLTDNRRSIKWRELDQWRDPAALWNEFLVMNVVPKAYATLILDSIKRLEMEKSSDFPLSVDVIYKLWPEASKVKVHWQPVLEPLFSELLQNAVIYSISCDWVRLEQVYFSELDENLEYTKTVLNYLQSSGKQIAKVPGNVDAAVQLTAASGT---TPVRKVTPAWVRQVLRKCAHLGCAEEKLHLLEFVLSDQAYSELLGLELLPLQNGNFVPFSSSVSDQDVIYITSAEYPRSLFPSLEGRFILDNLKPHLVAALKEAAQTR---------GRPCTQLQLLNPERFARLIKEVMNTFWPGRELIVQWYPFDENRNHPSVSWLKMVWKNLYIHFSEDLTLFDEMPLIPRTILEEGQTCVELIRLRIPSLVILDDESEAQLPEFLADIVQKLGGFVLKKLDASIQHPLIKKYIHSPLPSAVLQIMEKMPLQKLCNQITSLLPTHKDALRKFLASLTDSSEKEKRIIQELAIFKRINHSSDQGISSYTKLKGCKVLHHTAKLPADLRLSISVIDSSDEATIRLANMLKIEQLKTTSCLKLVLKDIENAFYSHEEVTQLMLWVLENLSSLKNENPNVLEWLTPLKFIQISQEQMVSAGELFDPDIEVLKDLFCNEEGTYFPP-SVFTSPDILHSLRQIGLKNEASLKEKDVVQVAKKIEALQVGACPDQDVLLKKAKTLLLVLNKNHTLLQSSEGKMTLKKIKWVPACKERPPNYPGSLVWKGDLCNLCAPPDMCDVGHAILIGSSLPLVESIHVNLEKALGIFTKPSLSAVLKHFKIVVDWYSSKTFSDEDYYQFQHILLEIYGFMHDHLNEGKDSFRALKFPWVWTGKKFCPLAQAVIKPIHDLDLQPYLHNVPKTMAKFHQLFKVCGSIEELTSDHISMVIQKIYLKSDQDLSEQESKQNLHLMLNIIRWLYSNQIPASPNTPVPIHHSKNPSKLIMKPIHECCYCDIKVDDLNDLLEDSVEPIILVHEDIPMKTAEWLKVPCLSTRLINPENMGFEQSGQREPLTVRIKNILEEYPSVSDIFKELLQNADDANATECSFLIDMRRNMDIRENLLDPGMAACHGPALWSFNNSQFSDSDFVNITRLGESLKRGEVDKVGKFGLGFNSVYHITDIPIIMSREFMIMFDPNINHISKHIKDKSNPGIKINWSKQQKRLRKFPNQFKPFIDVFGCQLPLTVEAPYSYNGTLFRLSFRTQQEAKVSEVSSTCYNTADIYSLVDEFSLCGHRLIIFTQSVKSMYLKYLKIEETNPSLAQDTVIIKKKSCSSKALNTPVLSVLKEAAKLMKTCSSSNKKLPSDEPKSSCILQITVEEFHHVFRRIADLQSPLFRGPDDDPAALFEMAKSG-QSKKPSDELSQKTVECTTWLLCTCMDTGEALKFSLSESGRRLGLVPCGAVGVQLSEIQDQKWTVKP---HIGEVFCYLPLRIKTGLPVHINGCFAVTSNRKEIWKTDTKGRWNTTFMRHVIVKAYLQVLSVLRDLATSGELMDYTYYAVWPDPDLVHDDFSVICQGFYEDIAHGKGKELTKVFSDGSTWVSMKNVRFLDDSILKRRDVGSAAFKIFLKYLKKTGSKNLCAVELPSSVKLGFEEAGCKQILLENTFSEKQFFSEVFFPNIQEIEAELRDPLMIFVLNEKVDEFSGVLRVTPCIPCSLEGHPLVLPSRLIHPEGRVAKLFDIKDGRFPYGSTQDYLNPIILIKLVQLGMAKDDILWDDMLERAVSVAEINKSDHVAACLRSSILLSLIDEKLKIRDPRAKDFAAKYQTIRFLPFLTKPAGFSLDWKGNSFKPETMFAATDLYTAEHQDIVCLLQPILNENSHSFRGCGSVSLAVKEFLGLLKKPTVDLVINQLKEVAKSVDDGITLYQENITNACYKYLHEALMQNEITKMSIIDKLKPFSFILVENAYVDSEKVSFHLNFEAAPYLYQLPNKYKNNFRELFETVGVRQSCTVEDFALVLESIDQERGTKQITEENFQLCRRIISEGIWSLIREKKQEFCEKNYGKILLPDTNLMLLPAKSLCYNDCPWIKVKDTTVKYCHADIPREVAVKLGAVPKRHKALERYASNVCFTTLGTEFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEICFVFDPRQHPVDRIFDDKWAPLQGPALCVYNNQPFTEDDVRGIQNLGKGTKEGNPYKTGQYGIGFNSVYHITDCPSFISGNDILCIFDPHARYAPGATSISPGRMFRDLDADFRTQFSDVLDLYLGTHFKLDNCTMFRFPLRNAEMAKVSEISSVPASDRMVQNLLDKLRSDGAELLMFLNHMEKISICEIDKSTGALNVLYSVKGKITDGDRLKRKQFHASVIDSVTKKRQLKDIPVQQITYTMDTEDSEGNLTTWLICNRSGFSSMEKVSKSVISAHKNQDITLFPRGGVAACITHNYKKPHRAFCFLPLSLETGLPFHVNGHFALDSARRNLWRDDNGVGVRSDWNNSLMTALIAPAYVELLIQLKKRYFPGSDPTLSVLQNTPIHVVKDTLKKFLSFFPVNRLDLQPDLYCLVKALYNCIHEDMKRLLPVVRAPNIDGSDLHSAVIITWINMSTSNKTRPFFDNLLQDELQHLKNADYNITTRKTVAENVYRLKHLLLEIGFNLVYNCDETANLYHCLIDADIPVSYVTPADIRSFLMTFSSPDTNCHIGKLPCRLQQTNLKLFHSLKLLVDYCFKDAEENEIEVEGLPLLITLDSVLQTFDAKRPKFLTTYHELIPSRKDLFMNTLYLKYSNILLNCKVAKVFDISSFADLLSSVLPREYKTKSCTKWKDNFASESWLKNAWHFISESVSVKEDQEETKPTFDIVVDTLKDWALLPGTKFTVSANQLVVPEGDVLLPLSLMHIAVFPNAQSDKVFHALMKAGCIQLALNKICSKDSAFVPLLSCHTANIESPTSILKALHYMVQTSTFRAEKLVENDFEALLMYFNCNLNHLMSQDDIKILKSLPCYKSISGRYVSIGKFGTCYVLTKSIPSAEVEKWTQSSSSAFLEEKIHLKELYEVIGCVPVDDLEVYLKHLLPKIENLSYDAKLEHLIYLKNRLSSAEELSEIKEQLFEKLESLLIIHDANSRLKQAKHFYDRTVRVFEVMLPEKLFIPNDFFKKLEQLIKPKNHVTFMTSWVEFLRNIGLKYILSQQQLLQFAKEISVRANTENWSKETLQNTVDILLHHIFQERMDLLSGNFLKELSLIPFLCPERAPAEFIRFHPQYQEVNGTLPLIKFNGAQVNPKFKQCDVLQLLWTSCPILPEKATPLSIKEQEGSDLGPQEQLEQVLNMLNVNLDPPLDKVINNCRNICNITTLDEEMVKTRAKVLRSIYEFLSAEKREFRFQLRGVAFVMVEDGWKLLKPEEVVINLEYESDFKPYLYKLPLELGTFHQLFKHLGTEDIISTKQYVEVLSRIFKNSEGKQLDPNEMRTVKRVVSGLFRSLQNDSVKVRSDLENVRDLALYLPSQDGRLVKSSILVFDDAPHYKSRIQGNIGVQMLVDLSQCYLGKDHGFHTKLIMLFPQKLRPRLLSSILEEQLDEETPKVCQFGALCSLQGRLQLLLSSEQFITGLIRIMKHENDNAFLANEEKAIRLCKALREGLKVSCFEKLQTTLRVKGFNPIPHSRSETFAFLKRFGNAVILLYIQHSDSKDINFLLALAMTLKSATDNLISDTSYLIAMLGCNDIYRIGEKLDSLGVKYDSSEPSKLELPMPGTPIPAEIHYTLLMDPMNVFYPGEYVGYLVDAEGGDIYGSYQPTYTYAIIVQEVEREDADNSSFLGKIYQIDIGYSEYKIVSSLDLYKFSRPEESSQSRDSAPSTPTSPTEFLTPGLRSIPPLFSGRESHKT-SSKHQSPKKLKVNSLPEILKEVTSVVEQAWKLPESERKKIIRRLYLKWHPDKNPENHDIANEVFKHLQNEINRLEKQAFLDQNADRASRRTFSTSASRFQSDKYSFQRFYTSWNQEATSHKSERQQQNKEKCPPSAGQTYSQRFFVPPTFKSVGNPVEARRWLRQARANFSAARNDLHKNANEWVCFKCYLSTKLALIAADYAVRGKSDKDVKPTALAQKIEEYSQQLEGLTNDVHTLEAYGVDSLKTRYPDLLPFPQIPNDRFTSEVAMRVMECTACIIIKLENFMQQKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3APK9-1", "uniprot_id": "A0A8M3APK9_DANRE", "id": "A0A8M3APK9-1", "name": "", "aln": "MATGQDPWLPWVIVSHDCLGTRVFQVPSSTVIRSIKTLIYEETDYPVSEQQLFHNGKMVHDGVEIGNLVPHGDHEIIMTLHGRGPRGGGRFGQTTPPLVDFLKDILRRYPEGGQILKELIQNAEDAGATEVKFLYDETEYGVESLWSHDMAQYQGTALYVYNDAVFTTEDWNGIQEIARSRKREDPLKVGRFGIGFNSVYHITDVPSIFSGDQIAMLDPHQMLFGVHESGQCWNLKSDIKEITELSDQFSPYFGLLGSSEKTIKDGNFPGTLFRFPLRMKPSQLSNNIYNKEKVLELFESFKVDADTVLLFLKSVQKVSLHVRESDGTERMLFQVTASDSQEDRMERPNSLKTLGQAIDSYSNGVPGSSVTCATYQLSIEARDETAKETQKTTWLVCNSVGGRGMCGELDSLADDLKFIPTIGIALPLTLID-EDKGATSSFSGRAFCFLPLPLGEESMTGLPVHVSGFFGLTDNRRSIKWREVDQWRDPAALWNELLIVTVIPRAYFTLIMETIQRIQTKKDQDFPLSPRGIYGAWPDPNRIRPRWKPILEPLLNDLLQHPVIYSISGSWVQVDETVFSDLDSSMDTAGTIIKYLQTSGMMLAQVPAYIDEALTMFVTKPG----SLRRVTPSFVRQTLRKCRHKGPSTEKLLLLEFILSDSCYNDLIGLELLPLQDETFAVFSSSVNDKDAVYIASQEYPRSLYPGLEGRFVLESIPPHVMTSLKEAAKSRVQQYLWGCSGRPCTQVQVLTPERSARLIKEVLTTAWPSRDFAVQWNPGDQEKKHPSASWLRMIWKHLYINFADDLSVFEDLPLIPNVPLADTLDCLELLRLKSPSPIVLVNEEEGPPSEDLLEVMKKLGCVILKQIDPCLHHPLLKNYIHQSSPSTLLQIMDRSTSQRLASQVSSLTVKQRLALRSFLAGLTDVTEKEKRIIQELPIFDKVGQKSKTDTSPLTLLKGARVLHHTAKHPLDVKLSINVVDCSDEATIRLVKLLNIEQVKSTECLKVIIQDIEKGFYTKEEVTKIMLWALTYLSFLKNENKAVISWLSSLKFIHTASEKLHSPTDFFDPELEILQNLFFMEEKVRFPPDDFMSSPDVLHSLRQLGLKNEVQLNEKDVLQVARKIEELQGNSKPEWDPILKKAKTLLTILNKQTKLVKSSEVQTNLQKLKWVPVCKDRPLNYPKSLAWRGDSCNISSLSEMCDISYAVLVGSSVSLVERTSAGMKKALKLSLEPQVDQVLQHLKAVNDWHQSQAFTTEDWYQFQQILCEIYEFMQAHLEDAREALKSLSFDWVWTGKTFASPGCTVLKPIPDLDLQPYLYSLPKTIAKFNKLFKFCGSIEEVVPSHVFEVVKTIRQRCEEEMTKQESKRNVLLLINILRWLYSSQIPVDADMHVPILYHKDPSKLVMKPIHECTYCDIKVEDLNDLLDDASEPIILVHDDIPMKTAEWLKVPCLSTRLINPENLGFEQSGQREPLTVRIKNILEEYPSVADIFKELLQNADDANATECSFLIDMRKNLEIRENLLDPGMIICHGPALWSFNNSVFSDTDFLNITRLGGSMKRCEADKVGKFGLGFNSVYHVTDIPIIMSREFMIMFDPNINHIGKHIRDKSNPGIKINWSKQQKRLRKFPNQFRPFINVFNCQLPLSLEAPYKYDGTLFRLPFRTEQEASASEISGIYYNTTDIYSLVDEFSICGHRLILFTQHVGTMVLKYLKCEEPNPAAAQDVVTINKSVWSSKAAYGP-LSILKSAAKVMKKVAATS-KVPTEVPKSGCIIRIIVEEYHNVFRRIVDLQSPLFRGSDEDPSSYFEMAAKGTQTKRLTDDMPQKGVENTNWLICSCMDVTEALKFSLNDSGKRLGLVPCGGIAVLLTEEENRKWTVKTSATPIGEVFCYLPLRIKTGLPVHINGCFAVTSNRKEIWKTDTKGQWNSIFMRHVIVQAYLAALNMLRSMAESGELLDYSYYAAWPDPGVVHDDFNLICQGVYQEIAKGADDDRAKVFSDGKTWVSIKNVRFLDDSLLCRPDIGSAAFKIFLKYLRKCGSQDLCAVELPEWVKEGFDDAGCKGKLMENTLTEKQFFSDVFFPHIQDIDKDLRDPLMYYVLNEKLEDFASILKETPCIPSSGPSKMLVLPSRLIHPEGRVAKLYNSEDGRFPEGSLRDYVNPVCLVKLLQLGMVKDDLSWEDLIERAESVLALNENDHTIACHRSSIILSLIDEKLKMRDPAANQYLDKFQNIKFLPFLTKPAGFSLPWHGNNFPQLTMFSAKELFTTEHQDTVCLMNPILNENSPSFKGCGPISLAVKDFLGLIRKPTVSLVISQLKELSKSFDG-VTLYQENITNACYKYLHEELLQSNAAKEEIMEELKTFSSILVENTYVEPLKVAFNLNFDAAPYLYQLPNKYRNSCRELFENVGVHASFTVETFSGVLQLIKNECGRKPLTEENFQLSRRIISEGIWSLIRDKSQEFCLSNYGEILLPDSNFTLQPSKSLCYNDCPWIKVRDTTVKYCHGDIPREVAVKLGAIPKRHKALERYASNICFTTLGSEFGQKEKLTSRIKSILNAYPSEKEMLKELLQNADDAKATEIYFVFDPRTHPTDRIFDDKWTPLQGPSLCVYNNQPFTEDDIRGIQNLGRGTKEANPGKTGQYGIGFNSVYHITDCPSFISNNDILCIFDPHARYAPGATSVSPGRMFRDLDSDFRSQFSDVLNLYLGNHFKLERSTMFRFPIRNVEMARISEISSAPASDRMVQNFLDKIRMDGAELLMFLNHMEKISICEIENGTGDLKTLYSVTAKITDGDRLKRKQFHASVLDSVYKKRQLTQIPVQQITYTMDIEDTDGNSTTWLICNRSGFSDMERVSKSVISAHKNEDITLFPRGGVAACTSHNYKKTHRAFCFLPLSLETGLPFHVNGHFALDSARRNLWRDDNGVGVRSDWNNNLMKVLIAPACVELLIQLKRRLFPGPDPTMTIFQGTPIHVVRDILRKYLSFFPVNRLDIQPDWYCLVKAIYLCIHADLKRLLPVVRAPHLDNSDMHSAVYISWVNTSTSTKGKAFFDNLLQDELQHLKNTEYNITTRKSVAENVFRLKAMLLDVGFNLIHSCDETASLYFCLEDAGIPVNYVTPEDVRSFLLTFSSPDTSCQVGKLPCRLQQSNFKLFHGLKLLVDYCFKDVEENDINIEGLPLLMTMDNILQVFDSRHPKFLTTYHELIATRKELFMHTLYIRYSNILIKAGVAKTFDINSFGDLLGSVLPRECKARSSVKWKENFPTESWLKSSWHFISEQLANKDDQAENKLKFETILEILKDWALLPGIKFMVSGNKLVVPEHDVLLPLSLIFAAIFPNGQNDKVFHTLMKGGCFQLAVNKICAKENPMLPLLAQHTANIDNPSSILRALEYMIQISAFKTASLTDKDFDALLLYFNCNLSNLA-QDDIQCLKLLPCYKAVSGRYICISNFGACYVLTKSIPSADIEKWAHNTSSAFLADNPQLKELYGFLGITPIDDLEVYLNHVLPKFDILSHDAKIQHVIYLKERLLAMEEQVSIKDKLFEKLEGLSFIYDSTNRLKPAKAFFDQTVKVFEVMLPQKAFIPNDFFRKIEQVSKPKSGTSYVPSWTTFLRNIGLKYVVSQQQVLQFAKEISIKAHTENWSKEKVQTIVDVLLNHIFNDRTDLFDGTFLKELSMISFLCPERAPAELVHLHAQYQEMNGTVPLIRFSGSQVNPKFKQTDIMQLLWTSCPILPERATPASIKDQEGNTLPSQEQLDLILTMLNVNVEPPLEKVISNCKNICSVTNLDDDTVKTRNKVLRSIYEFLIADKNDFRFQLRGVAFVMVEEGWKLLKPEEVVINLDNESDFKPYLYKLPLELGTFHQLFKLLGTEDIVSTKQYVEVLCRIFRISEGKQLDPNEMRTVKRTVSGLFKSLQNDAVQVRKDLENLRDLIFYLPSHDGRLAKSNTLVFDDAPHYKSRIQGNVGVQMLVDMSQCYLGKDHAFHTKMIMLLPQKLRPRLLSSILEEQLDEESPKMCQFGALCSLQGRLQLLLSSEQFITGLIRIMKHENENAYMVNEEKAIRLCKALCEGLKVSCFEKLQTTLRVKGCSPIPHSRSETLAFLKRYGSAVIHLYIQHSDSKDINFLLALAMTLKSATDNLISDTSYLIAMLGCNDIYRITEKLDNLGVKYDTTEPSKLELPLPGTPIPAEIHHLLLMDPMNVFYPGEYVGYLVDSEGGDILGTYQPTYTYAIIVQEVEREEDDSPSVLGKCFQIDIGYSEYKIVSSLDLYKFSRQDDGTHIRDGTP-TPTSPLEGHSPRARMVPPLFPGKENRRAPPTEAS-PKKVKFNALPEILKEVSSVVEQAWKLSETERKKIIRRLYLKWHPDKNAENLDIATEVFKHLQNEINRMEKQTQAEQTTDRASRRPFSSSSTRFQSEKFSFQRFYTSWNQEATSHKSEKQQ-FREQYNNYAGTSHSNRFFVPPSFKSVGNPVEARRWLRQARANFSAARNDLHKNANEWVCFKCYLATKLALIAADYAVRGKSDKDVKPTALAQKVEEYNTQLTGLAKDVHILEGYGVDSLRTRYPDLLPFPQIPNDRYTSEVAMRVMECTARIIIKLEAFVQQKI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * *: * * .*:* *.. . :: . *.:* *: **.:**:**:*::..: : * ::**:*. :::.*:.:* :****************************************************:**.*:***:*** ***.******:****.***:**********::**********************.*******.****** *** **********.* ***.**.***:*:.*::**:::*: :*.****:******::*****.*:*.*:******:**:.************* ***:***:****:::*:**:*:.: : *****:* ** **..*.: *...:**.**::.* .:*::*::***:***********:..:******:***:* **:*:.*: * * :** *.***:******** **** ******:*****************:***********: *::.*:*::* ***:::*:*:: :*..***** ** **:..::: :*:*:* **:.:*:*:.****:. .**::::. **:** .:: : ::::*** ** :*:**. : *: : .:. .:*:*** :***.**** * * : *** ****:***..*.:*:********. *. *****.*:*.:**:* *:****:*.**.*::*:.: **::::*****::* ******:*:*.*** *******:.* **.*:: *** * .:::.*** ***:*:**:***:*::**::*:::****.. * *:**:**: ** ::* :* *. .* * ::::*** .:**::*..::***:*:***.. **::****:: . *:*..*::** .:: ***.***.*** :**********.**.::.:.*. . *. * ***.:**.**** * :::**:.*:*.********.::*:**::*:*.***.:::** :.**::****::*** * ** ***** *:.** .****: :. :: :. ::***::*:*::** ** . *** .::***:******:***** .*:****:***:*** ** .: : * ::******* :***: .*::*** : *:*:****.**:** *** **.*:** **:.: .:*** .:*:*:***:.*** ..::::* : :* :. **:*:* * **: *::*: **:****:** *** **: **.:.::::::*.: ******.*.. . :*:** ********:.:***:***::*** ******:...*: *::.: :.:::::::***:*: *::**:*****.***...: *** : ::****:******* ******:******:*: *******:************************:*************************:********************:****:*::********** ************ ***:**:****** *:** *.***************:**********************.***:*:***********************:***:**.*****::****.*:******.***:***..**:*. ***:**********:******:*** * :* ***** **.**: ***.: *:*. .*** * **:**.***:**. :::. *:*:: ***.**::* ***:*:*****.*********.*:**:: **** .* *:*: :*::.** *: *.**:*:***. *******.:**:********.:.* * * :::*****. *****************:**********************:**: *******:*** .*.:**.:* .*** **:***.****.:*****.:**:*.*::**:* ..: ::*****. ***:*********:* * *:************:* **::*******. ** **::**** *:***::******:****:**:*: :****** :*****:::*:.:*: ***:*.* .: *****************:: :***** ** :**:**: *:**:****.***: *:*::*** ** :*:.**. ** ****:*********::** *::: *:*.* ************* *:**.* ***:*.:::*:*:** ***::******* **:***.:*****:****::****.***.***:::**.*. :***************** ::*.: :* *:::**.*. *****.**:. **:*:***:************:*. *****.***: * *** *: **: *.:* * * :*******.*************:* **** .***:*****:*: * *:*************:*::*****.************:*************:***: *:***************************************** ****** **.********:*****:*************:*******:****.** ***:*******************.**** **************:**********:***:******:****.****:..******:**.***::*****.*:*******:***:* ********************::.** *:.****..*****************:*** *****.:*********** **::** ************.*::*********:*:************* :*****.***********************************************.**..***** ********:* ***.***::::*.******:* *:*:**********:*** ******:* *** *:**********::*.**:**** *:*:* ***.* :.***************::*******:*****:*** :**::****::.*****.**.** ** ***.**** *:****:*******.*::*********:*:****.***********.**.::::******:*:*.:** **.::***********.:**:***:***::**.:*::. ***.***.**.***.****** *::...***:**.:*****.:******.:: .:** * * *: ::: ********* ** ** .:***** ***:****:. *:***.*.*****:***.**:***:****:*:..::***: *****:.*:***:*:.**:* *:*:: .* ::**:***:******.:* ***:: ** *****::****:.*.:**:***********::***::.:***** :: :***** .:* .*:*******:*:***:: **:***::*:****:** : ** . *::******.* :*:*:..*** ** *:*:**:*******:* ***::**:*:**: ***. . ::.**. ********: :****:********::*:*******.:*. **:**:***::* **:.*.******:*.********** :::*.****:***:***:*.*:******** *::************:*** ***:***. * .****: :*.*****::***:***.**:***.:*.**:: **** ********** *:*.:**************:**************: *:********************* ******:*********.***: ****************.*****:*****:*:**.**** *** :****:**:*.**. ****************:*******:*********.****:***:********************:**:**********************************:**::.************ ******************* .*********:*****:*.*** *********************************************** ****.******::********:**********: ********************:***** *:*****************: *..*.*** :********************** ::.:: **.:* ***** * :* * :****.*:*.::. .:: *:*:*.*:********:*********.*:******************.** ***.************:***: :*.:******.**:*::****:*:*******************:** :*: ** ::*:******:******************************************:****************************:***. ** **::*** **.******:****************:************* ****** *:***:", "identical_positions": 3136, "similar_positions": 1046, "identity": "68.19%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-148", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P29758-1", "uniprot_id": "OAT_MOUSE", "id": "P29758-1", "name": "Ornithine aminotransferase, mitochondrial", "aln": "---MLSKLASLQTIA-ALRRGVHTSVASATSVAT-KKTEQGPPSSEYIFERESKYGAHNYHPLPVALERGKGIYMWDVEGRQYFDFLSAYGAVSQGHCHPKIIDAMKSQVDKLTLTSRAFYNNVLGEYEEYITKLFNYNKVLPMNTGVEAGETACKLARRWGYTVKGIQKYKAKIVFADGNFWGRTLSAISSSTDPTSYDGFGPFMPGFETIPYNDLPALERALQDPNVAAFMVEPIQGEAGVIVPDPGYLTGVRELCTRHQVLFIADEIQTGLARTGRWLAVDHENVRPDMVLLGKALSGGLYPVSAVLCDDEIMLTIKPGEHGSTYGGNPLGCRIAIAALEVLEEENLAENADKMGAILRKELMKLPSDVVTSVRGKGLLNAIVIRETKDCDAWKVCLRLRDNGLLAKPTHGDIIRLAPPLVIKEDEIRESVEIINKTILSF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P04181-1", "uniprot_id": "OAT_HUMAN", "id": "P04181-1", "name": "Ornithine aminotransferase, mitochondrial", "aln": "---MFSKLAHLQRFA-VLSRGVHSSVASATSVAT-KKTVQGPPTSDDIFEREYKYGAHNYHPLPVALERGKGIYLWDVEGRKYFDFLSSYSAVNQGHCHPKIVNALKSQVDKLTLTSRAFYNNVLGEYEEYITKLFNYHKVLPMNTGVEAGETACKLARKWGYTVKGIQKYKAKIVFAAGNFWGRTLSAISSSTDPTSYDGFGPFMPGFDIIPYNDLPALERALQDPNVAAFMVEPIQGEAGVVVPDPGYLMGVRELCTRHQVLFIADEIQTGLARTGRWLAVDYENVRPDIVLLGKALSGGLYPVSAVLCDDDIMLTIKPGEHGSTYGGNPLGCRVAIAALEVLEEENLAENADKLGIILRNELMKLPSDVVTAVRGKGLLNAIVIKETKDWDAWKVCLRLRDNGLLAKPTHGDIIRFAPPLVIKEDELRESIEIINKTILSF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F8W5L3-1", "uniprot_id": "F8W5L3_DANRE", "id": "F8W5L3-1", "name": "Ornithine aminotransferase", "aln": "MNSMKSLMRGVSRVTPSLTRAVHSGMRTSSSAASRAKTQERPMTSEEVFAREDRYGAHNYHPLPVALERGEGVHMWDVEGRRYFDFLSAYSAVNQGHCHPKIIAALTAQASRLTLTSRAFYNDILGAYEQYITGLFGYDKVLPMNTGVEGGETACKLARKWAYSVKGIPKYEAKIVFAAGNFWGRTMAAISSSTDPSSYDGFGPFMPGFELVPYNDIPALEKALQDPHVAAFMVEPIQGEAGVVVPDAGYLQKVRELCTKYNVLFIADEVQTGLCRTGRRLAVDHEAVRPDLVILGKALSGGVYPVSAVLCDDEVMLTIKPGEHGSTYGGNPLACRVAIAALEVLEEENLAANAERMGQILRAELNKLPREIVSGVRGKGLLNAIIIKETKDYDAWQVCLRLRDNGLLAKPTHGDIIRLAPPLTINEQEVRECVEIISRTILSF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : :. .: * *.**:.: :::*.*: ** : * :*: :* ** :****************:*:::******:******:*.**.********: *:.:*..:**********::** **:*** **.*.**********.*********:*.*:**** **:****** *******::********:************: :****:****:*****:***************:***.*** ******:::*******:****.**** ****:* ****:*:********:**********::******************.**:************** **:::* *** ** *** ::*:.**********:*:**** ***:*********************:****.*:*:*:**.:***.:*****", "identical_positions": 322, "similar_positions": 86, "identity": "72.52%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-149", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y5Q0-1", "uniprot_id": "A0A8I5Y5Q0_RAT", "id": "A0A8I5Y5Q0-1", "name": "Phosphorylase b kinase regulatory subunit", "aln": "MAGEEG--LMSEVSWKLLERRARAKRSGSVYEPLKSINLPRPDNETLWDKLDHYYRIVKSTMLTYQSPTTGLFPTKTCGGDQKSKVHESLYCAAGAWALALAYRRIDDDKGRTHELEHSAIKCMRGVLYCYMRQADKVQQFKQDPRPTTCLHSVFNVHTGDEVLSYEEYGHLQINAVSLFLLYLVEMISSGLQIIYNTDEVSFIQNLVFCVERVYRVPDFGVWERGSKYNNGSTELHSSSVGLAKAALEAINGFNLFGNQGCSWSVIFVDLDAHNRNRQTLCSLLPRESRSHNTDAALLPCITYPAFALDDEALFSQTLDKVIRKLKGKYGFKRFLRDGYRTPLEDPNRRYYKPAEIKLFDGIECEFPIFFLYLMIDGVFRGNLEQVKEYQDLLTPLLHQTTEGYPVVPKYYYVPADFVEYEKRNPGSQKRFPSNCGRDGKLFLWGQALYIIAKLLADELISPKDIDPVHRFVPLQNQRNVSMRFSNQGPLENDLVVHVALVAESQRLQVFLNTYGIQTQTPQQVEPIQIWPQQELVKAYFHLGINEKLGLSGRPDRPIGCLGTSKIYRILGRTVVCYPIIFDLSDFYMSQDVLLLIDDIKNALQFIKQYWKMHGRPLFLVLIREDNIRGSRFNPILDMLAAFKKGIIGGVKVHVDRLQTLISGAVVEQLDFLRISDTEKLPEFKSFEELEFPKHSKVKRQSSTADAPELR-QEPDITITEWKNKSTHEILQKLNDCGCLAGQTILLGILLKREGPNFITMEGTVSDHIERVYRRAGSKKLWSVVRRAASLLNKVVDSLAPSITNVLVQGKQVTLGAFGHEEEVISNPLSPRVIKNIIYYKCNTHDEREAVIQQELVIHIGWIISNNPELFSGMLKIRIGWIIHAMEYELQIRGGDKPAVDLYQLSPSEVKQLLLDILQP----QQSGRCWLNRRQIDGSLNRTPPGFYDRVWQILERTPNGIVVAGKHLPQQPTLSDMTMYEMNFSLLVEDMLGNIDQPKYRQIIVELLMVVSIVLERNPELEFQDKVDLDKLVKEAFHEFQKDESRLKEIE------KQDGMTSFYNTPPLGQRGTCSYLTKVVMNSLLEGEVKPTN------------EDSCLVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TSH2-1", "uniprot_id": "KPBB_MOUSE", "id": "Q7TSH2-1", "name": "Phosphorylase b kinase regulatory subunit beta", "aln": "MANSP----DAAFSSPALLR------SGSVYEPLKSINLPRPDNETLWDKLDHYYRIVKSTMLMYQSPTTGLFPTKTCGGEEKSKVHESLYCAAGAWALALAYRRIDDDKGRTHELEHSAIKCMRGILYCYMRQADKVQQFKQDPRPTTCLHSVFSVHTGDELLSYEEYGHLQINAVSLFLLYLVEMISSGLQIIYNTDEVSFIQNLVFCVERVYRVPDFGVWERGSKYNNGSTELHSSSVGLAKAALEAINGFNLFGNQGCSWSVIFVDLDAHNRNRQTLCSLLPRESRSHNTDAALLPCISYPAFALDDEALFSQTLDKVIRKLKGKYGFKRFLRDGYRTPLEDPNRRYYKPAEIKLFDGIECEFPIFFLYMMIDGVFRGNLEQVKEYQDLLTPLLHQTTEGYPVVPKYYYVPADFVECEKRNPGSQKRFPSNCGRDGKLFLWGQALYIIAKLLADELISPKDIDPVQRFVPLQNQRNVSMRYSNQGPLENDLVVHVALVAESQRLQVFLNTYGIQTQTPQQVEPIQIWPQQELVKAYFHLGINEKLGLSGRPDRPIGCLGTSKIYRILGKTVVCYPIIFDLSDFYMSQDVLLLIDDIKNALQFIKQYWKMHGRPLFLVLIREDNIRGSRFNPILDMLAAFKKGIIGGVKVHVDRLQTLISGAVVEQLDFLRISDTEKLPEFKSFEELEFPKHSKVKRQSSTADAPEAQ-HEPGITITEWKNKSTHEILQKLNDCGCLAGQTILLGILLKREGPNFITMEGTVSDHIERVYRRAGSKKLWSVVRRAASLLNKVVDSLAPSITNVLVQGKQVTLGAFGHEEEVISNPLSPRVIKNIIYYKCNTHDEREAVIQQELVIHIGWIISNSPELFSGMLKIRIGWIIHAMEYELQVRGGDKPAVDLYQLSPSEVKQLLLDILQP----QQSGRCWLNRRQIDGSLNRTPPEFYDRVWQILERTPNGIVVAGKHLPQQPTLSDMTMYEMNFSLLVEDMLGNIDQPKYRQIIVELLMVVSIVLERNPELEFQDKVDLDRLVKEAFHEFQKDESRLKEIE------KQDDMTSFYNTPPLGKRGTCSYLTKVVMNSLLEGEVKPSN------------EDSCLVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q93100-1", "uniprot_id": "KPBB_HUMAN", "id": "Q93100-1", "name": "Phosphorylase b kinase regulatory subunit beta", "aln": "MAGAAG--LTAEVSWKVLERRARTKRSGSVYEPLKSINLPRPDNETLWDKLDHYYRIVKSTLLLYQSPTTGLFPTKTCGGDQKAKIQDSLYCAAGAWALALAYRRIDDDKGRTHELEHSAIKCMRGILYCYMRQADKVQQFKQDPRPTTCLHSVFNVHTGDELLSYEEYGHLQINAVSLYLLYLVEMISSGLQIIYNTDEVSFIQNLVFCVERVYRVPDFGVWERGSKYNNGSTELHSSSVGLAKAALEAINGFNLFGNQGCSWSVIFVDLDAHNRNRQTLCSLLPRESRSHNTDAALLPCISYPAFALDDEVLFSQTLDKVVRKLKGKYGFKRFLRDGYRTSLEDPNRCYYKPAEIKLFDGIECEFPIFFLYMMIDGVFRGNPKQVQEYQDLLTPVLHHTTEGYPVVPKYYYVPADFVEYEKNNPGSQKRFPSNCGRDGKLFLWGQALYIIAKLLADELISPKDIDPVQRYVPLKDQRNVSMRFSNQGPLENDLVVHVALIAESQRLQVFLNTYGIQTQTPQQVEPIQIWPQQELVKAYLQLGINEKLGLSGRPDRPIGCLGTSKIYRILGKTVVCYPIIFDLSDFYMSQDVFLLIDDIKNALQFIKQYWKMHGRPLFLVLIREDNIRGSRFNPILDMLAALKKGIIGGVKVHVDRLQTLISGAVVEQLDFLRISDTEELPEFKSFEELEPPKHSKVKRQSSTPSAPELG-QQPDVNISEWKDKPTHEILQKLNDCSCLASQAILLGILLKREGPNFITKEGTVSDHIERVYRRAGSQKLWLAVRYGAAFTQKFSSSIAPHITTFLVHGKQVTLGAFGHEEEVISNPLSPRVIQNIIYYKCNTHDEREAVIQQELVIHIGWIISNNPELFSGMLKIRIGWIIHAMEYELQIRGGDKPALDLYQLSPSEVKQLLLDILQP----QQNGRCWLNRRQIDGSLNRTPTGFYDRVWQILERTPNGIIVAGKHLPQQPTLSDMTMYEMNFSLLVEDTLGNIDQPQYRQIVVELLMVVSIVLERNPELEFQDKVDLDRLVKEAFNEFQKDQSRLKEIE------KQDDMTSFYNTPPLGKRGTCSYLTKAVMNLLLEGEVKPNN------------DDPCLIS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BDU6-1", "uniprot_id": "A0A8M2BDU6_DANRE", "id": "A0A8M2BDU6-1", "name": "Phosphorylase b kinase regulatory subunit", "aln": "MASLA------DVGWKLLEFKARSKRSGSIYEPLKLSILHRED-EPLWEKLDRFYSAVKSTILNYQSPTTGLFPVKTCSTCKEAKVRDSLYCAASIWALALAYRRIDDDMGRTHELEHSAIKCMRGIMYCYMRQSDKVENFKQDPSPSTCLHSIFNVDTGDEVYPYKEYNHLQIDALSLFLLYLVEMICSGLQIIYNTDEVSFIQNLVFCVERAYRVPDFGMWERGSKYNNGSTELHSSSVGLAKAALEAINGFNLFGNQGCSWSVIFVDLDAHNRNRQTLCSLLPRESRSHNTDSALLPCISYPAFAVDDDALYSQTLDKIVRKLKGKYGFKRFLRDGFRTANEDKNRRHYKPAEMKLFDGIECEFPIFYIYMMIDGVFRGNPDQVKEYQELLQAVIFQSFEGHAVIPKYYHVPADFVEAEQKKHGSQKRFPSNSGRDGMLFLWGQALYNIAKLLVDGLISPKDIDPIHRYVPRQDQRNVSMRYSNQGPIENDVVIHVALIAESQRLQVFLNTYGIQTQTPQQVEPIQIWPQKELVKAYRFLAVNKKLGLSGRPERPVGCIGTCKIYRILGKTVVCYPIVFDLSDFYLSQDVMLLIDDIKNALQFIKQCWKMPGRPLFLVLIREDNIKGSRFNPILDMLASFKKGNIGGVKVHVDRLQTLISGAVVEQLDFLRVN-EAEIPEFKSFEELELPKHSKVKRQTSTPNASDLE-QQPEINDEEWFNKSTFEILQKFNDCDCLASQAQLASILLKKEGPEFFNTNENLKDELERIYRRAGSRKLWLAVRSAAAVIQKFAGSIAPHITTMLVHGKQVTLGLFGHEEIVISNPLSPGVIKDIIYSKCSPHGEREAVLQQELVIHIGWIISNNPELFSGMLKIRVGWIVQAMKHELKIRAGDMPPQDIYQMSPSDVKQLLLDVLQS----QQSGRSWLNRRQIDGSLNRTPLGFYDRVWQILERTRNGIMVGGKHLPQQPTLSDMTMYEMNFSLLVEDTLKNIVLPEYRQIIVELLMVVSIVLERNPELEFQEPVDLDKLVKEAFADFQKDRSKLEGTE------KRDTMEAFYNTPALGKQSTSSYLTKAVMIQLLQGEVKPSK------------DDPCSVS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLS1-1", "uniprot_id": "KPBB_DROME", "id": "Q9VLS1-1", "name": "Probable phosphorylase b kinase regulatory subunit beta", "aln": "MRDVPKSLGLSVTTPGGSSGAPDSGRHNSLEEINLDQFLKTSNYEDTVKQLDIYYGIVKRQLLRYQSPITGLFPVMSTDQVVGS-VRDSVYCASAVWSLYQAYRRIDDDRGKSYELGQSTVKCMRGILECWVKQASRVELFKQRQSNQHALHSKFQLHTGEKIYPDEFYNHLQIDCVSLYLLFLVQMITSGLQIIYTHDEVAFVQNLVYYVERAYRTPDFGMWERGSKYNNGTPEIHASSIGMAKSALEAINGCNLFGEKGASWSVVYVDIDAHNRNRSIFETMLPRESSSKGVDASLLLTLSFPAFASHEDRLVEQTKQNVVNRLRCKMGFKRFTRDGFLSKNEDKSRRYYHSGELKEFEGLECEWPLFFIAMIIDGVFKNNNEQIEEFQNDLRRCLRTDVNGDPVVTMYYAPDGD---------GSYMRAPSQS-----LFLWGQSFFIIAQLLTAGLLHINELDPIRRYLPSYNRPRRAGRYSAFQGTATDLVVQIVLIAESMRLQAMMATYGIQTQTPHEVEPVQIWSSTELIKVYQHLGVNNKVGLSGRPCRPVGSLGTSKVYRICGMTVLCYPLIFEVSDFYLYRDMALLIDDIKTELQFVGKYWRLSGRPTVCLLIREEHMRDPQFKEMLDLLAMLKKGYCDGMKVRIGRLQNLISSSCIEHLDFMNQSDLTDN--ENAFSQIN---HEYIGYQSLTDVPKALTYVEEKISVAHFDTKPTPDIINALRSTDSIYCLCQLWGIILNREGPHFEVNGLNVNTALTQLYHRAGSLRYWRAVRYCSSLLHHIVDSISPFITTVLVNGKELTVGIIGQKETVFDKPMTPAEIQNVMYTSVQPYDVIQAVLQQEVVLYCGRLIATNPSMFRGILKIRIGWVLEAMRIYLQISG--QQSIDVDNLSPFQVRILLQKVLTVSEWAVEEKLTTLQRRQLEGCLCRVPKHFYNKIWEILQRTPQGILTQGHHLPATPTLTNMSRGELTFNLLVEETLICIDRPERRQITVELLCIVATILNRNPELHFKQALDLDGILAEAFAMYCKDNNIQHQPKPEHEQTKNEDLKAFYSLP---YSETTGYLARAAVNKVLQGGIFSTNEEDVQLDGDRLHDDNCKVS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .*: * * : * .:** :* ** :* **** *****. : . : :::*:***:. *:* ******** *:::** :*::*****:: *:::*:.:*: *** .*** *.:.**::: . : *.****:.:**:**:**:** *******. ***:*:****: ***.**.****:**********:.*:*:**:*:**:******* ****::*.****::**:*******. : ::***** *:..*::** :::**** .:: * .** ::::.:*: * ***** ***: : ** .* :*:..*:* *:*:***:*:*:: ::*****:.* .*::*:*: * : :* .*:. ** .* ** * **:. ******::: **:**. *: :::**::*::* :: . : *:* .*:*:::.*:*** ***.:: *********::***:***.. **:*.* *.:*:*:****** **:*.:**.*:*** * **:***::*::****: :*: *******. ***: : *:: *** . :****::::..:*: :**:** :*** .*:**::.***.***.: :*:***:. . . ::*.::: *. : *: * . : :. .: *.* :*:: :.. ..: * .*:*::***.* .:. : ::*:**** : * .** ::. ::. .*::* **..**:**::*:* :*::* *:.:*::* *::::* . ..:. :**:***:*:: * :*:..*.:* *:****:**::.**. *:: . . *: ::** :*: ** .:* :. *:***::*.* *.* **:::*:**:** :**:. *:*** ***::*: *:.*.****: * * *: *** **** :*: :*:*****.*:: :*** :: *** : **.. . : *.: : :**. * * .**::..: :*:* : ..: :* * :*", "identical_positions": 442, "similar_positions": 365, "identity": "39.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-156", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AY88-1", "uniprot_id": "KDF1_RAT", "id": "Q6AY88-1", "name": "Keratinocyte differentiation factor 1", "aln": "MPRPGQPRPSSGPPRLGPWERPT----------------ELCLETNDERSQPPPGRRTRRPDPKDPGHHGPESITFISGSAEPANEPPTCCLLWRPWGWDWCRAAFCFRRCRDCLQRCGACVRSCSPCLSAGDPIEGSSEAAWAKEHNGVPPSPDRAPPSRRDGQKLKTSMGSSFSYPDVKLKGIPVYPYRHATSPVPDADSCCKEPLADPPPTRHSLPSTFTSSPRGSEEYYSFHESDLDLPEMGSGSMSSREIDVLIFKKLTELFSVHQIDELAKCTSDTVFLEKTSKISDLISSITQDYHLDEQDAEGRLVRGIIRISTRKSRSRPQTSEGRSARSTAP------AAAPDSGHETMVGSGLSQDELTVQISQETTADAIARKLRPYGAPGYPASQDSSFQGTDTDSSGAPLLQVYC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A9F4-1", "uniprot_id": "KDF1_MOUSE", "id": "A2A9F4-1", "name": "Keratinocyte differentiation factor 1", "aln": "MPRPGQPRPSSGPPRLGPWERPS----------------ELCLETNDERSQPPPGRRTRRPDPKDPGHHGPESITFISGSAEPANEPPTCCLLWRPWGWDWCRAAFCFRRCRDCLQRCGACVRGCSPCLSAGDPIEGSAEAAWAKEHNGVPPSPDRAPPSRRDGQRLKTSMGSSFSYPDVKLKGIPVYPYRHATSPVPDVDSCCKEPLAEPPPTRHSLPSTFTNSPRGSEEYYSFHESDLDLPEMGSGSMSSREIDVLIFKKLTELFSVHQIDELAKCTSDTVFLEKTSKISDLISSITQDYHLDEQDAEGRLVRGIIRISTRKSRSRPQTSEGRSARSTAP------AAAPDSGHETMLGSGLSQDELTVQISQETTADAIARKLRPYGAPGYPASQDSSFQGTDTDSSGAPLLQVYC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NAX2-1", "uniprot_id": "KDF1_HUMAN", "id": "Q8NAX2-1", "name": "Keratinocyte differentiation factor 1", "aln": "MPRPGHPRPASGPPRLGPWERPT----------------ELCLETYDKPPQPPPSRRTRRPDPKDPGHHGPESITFISGSAEPALESPTCCLLWRPWVWEWCRAAFCFRRCRDCLQRCGACVRGCSPCLSTEDSTEGTAEANWAKEHNGVPPSPDRAPPSRRDGQRLKSTMGSSFSYPDVKLKGIPVYPYPRATSPAPDADSCCKEPLADPPPMRHSLPSTFASSPRGSEEYYSFHESDLDLPEMGSGSMSSREIDVLIFKKLTELFSVHQIDELAKCTSDTVFLEKTSKISDLISSITQDYHLDEQDAEGRLVRGIIRISTRKSRARPQTSEGRSTRAAAPT-----AAAPDSGHETMVGSGLSQDELTVQISQETTADAIARKLRPYGAPGYPASHDSSFQGTDTDSSGAPLLQVYC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F2A2-1", "uniprot_id": "E7F2A2_DANRE", "id": "E7F2A2-1", "name": "", "aln": "MPGHSTGTHHKTRPHSSSRSRADGYRQNRTCSKDSSTSQETYKDAYSEQPRSTDSQLPRKSQTQYANGRGSETLGFIPGSADSP-QGTQACGSCASLGWSDCKALLCCILTCGLYGSR----KPCLPPDESSTDNSLKAEPEPKKTNGLMALSNPTSGINLEPSKPRKLPNSDSFKYPDVYFAGK-----------------KVEYPINTDAPPRRTRTTGKSDNQRPISDTSIYSREDLDLDDLDDG---GTDIDSLITKKLLELYKLHQIEQLAKCTSDVSFSRKTNEISDLINSIAQDYNLEEQEAECRLVHGVIRISTRHKSSKGCKRDYKSHDAVQHTNGKRDGTLPDSGNETMTFT-FSDGDPEMFVSDLTPSDELVRNMKGN-------MRKNYYSSSATDSSGAPLLR---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . . *: .. .*. * :: .: .:.. .: .*:.:.: .. :*.*:: **.***:.. : . .* . *. *:* :* . : * * .: . .:*. * :. :. * : . . .: * . ..**.**** : * : *: .* *:: .: :.. * .: : ..**** ::..* . :** ** *** **:.:***::*******. * .**.:*****.**:***:*:**:** ***:*:******:. :: . : :* :. .: ****:*** : :*:.: : :*: *.:* :.*::: :.. :..: *********: ", "identical_positions": 109, "similar_positions": 134, "identity": "26.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-165", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2X5-1", "uniprot_id": "ACK1_RAT", "id": "Q5U2X5-1", "name": "Activated CDC42 kinase 1", "aln": "--------------------------MQPEEGTGWLLELLSEVQLQQYFLRLRDDLNITRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKRRKAMCKRKSWMSKVFSGKRQEAEFPSHHSQSTFRKPSPTPGGLAGEGTLQSLTCLIGEKDLRLLEKLGDGSFGVVRRGEWDA-PAGKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDGHYVMQEHRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLEAQPTDMRALQDFEEPDKLHIQMNDVITVIEGRAENYWWRGQNTRTLCVGPFPRNVVTSVAGLSAQDISQPLQNSFIHTGHGDSDPRHCWG----FPDRIDELYLGNPMDPPDLLSVELSTSRPTQHLGRMK----------------------------------------KPTYDPVSEDPDPLSSDFKRLGLRKPALPRG--LWLAKPS-ARVPGTKAGRSSGG----EVTLIDFGEEPVAPTPRP------CAPSLAQLAMDACSLLDKTPPQSPTRALPRPLHPTPVVDWDARPLPPPPAYDDVAQDEDDFEVCSINSTLVSAGLPTGPSQGETNYAFVPEQAQLPPALEDNLFLPPQGGGQPPSSAQTAEIFQALQQECMRQLQVPTGQLTPSPTPG-------GDDKPQVPPRVPIPPRPTRPRVGLSPAPLGEEE--ASRWPGPSSPPRVPPREPLSPQGSRTPSP----------LVPPGSSPLPHRLSSSPGKTMPTTQSFASDPKYATPQVIQAPG----PRAGPCILPIVRDGRKVSSTHYYLLPERPPYLERYQRFLREAQSPEEPAALPVPPLLPPPSTPAPAAPTATVRPMPQAAPDPKANFSTNNSNPGAQP---PSLRASARLPQRGCPGDGQEAARPADKVQMLQAMVHGVTTEECQAALRSHSWSIQRAAQYLKVEQLFGLGLRPRVECHKVLEMFDWNLEQAGCHLLGSCGPAHHKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O54967-1", "uniprot_id": "ACK1_MOUSE", "id": "O54967-1", "name": "Activated CDC42 kinase 1", "aln": "--------------------------MQPEEGTGWLLELLSEVQLQQYFLRLRDDLNITRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKRRKAMCKRKSWMSKVFSGKRLEAEFPSQHSQSTFRKPSPTPGSLPGEGTLQSLTCLIGEKDLRLLEKLGDGSFGVVRRGEWDA-PAGKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTLPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMAYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLEAQPTDMRALQDFEEPDKLHIQMNDVITVIEGRAENYWWRGQNTRTLCVGPFPRNVVTSVAGLSAQDISQPLQNSFIHTGHGDSDPRHCWG----FPDRIDELYLGNPMDPPDLLSVELSTSRPTQHLGRVKREPPPRPPQP-------------------------AIFTQKTTYDPVSEDPDPLSSDFKRLGLRKPALPRG--LWLAKPS-ARVPGTKADRSSGG----EVTLIDFGEEPVVPTPRP------CAPSLAQLAMDACSLLDKTPPQSPTRALPRPLHPTPVVDWDARPLPPPPAYDDVAQDEDDFEVCSINSTLVGAGLPAGPSQGETNYAFVPEQAQMPPALEDNLFLPPQGGGKPPSSVQTAEIFQALQQECMRQLQVPTGQLTPSPTPG-------GDDKPQVPPRVPIPPRPTRPRVELSPAPSGEEE--TSRWPGPASPPRVPPREPLSPQGSRTPSP----------LVPPGSSPLPHRLSSSPGKTMPTTQSFASDPKYATPQVIQAPG----PRAGPCILPIVRDGRKVSSTHYYLLPERPPYLERYQRFLREAQSPEEPAALPVPPLLPPPSTPAPAAPTATVRPMPQAAPDPKANFSTNNSNPGARP---PSLRAAARLPQRGCPGDGQEAARPADKVQMLQAMVHGVTTEECQAALQSHSWSVQRAAQYLKVEQLFGLGLRPRVECHKVLEMFDWNLEQAGCHLLGSCGPAHHKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07912-1", "uniprot_id": "ACK1_HUMAN", "id": "Q07912-1", "name": "Activated CDC42 kinase 1", "aln": "--------------------------MQPEEGTGWLLELLSEVQLQQYFLRLRDDLNVTRLSHFEYVKNEDLEKIGMGRPGQRRLWEAVKRRKALCKRKSWMSKVFSGKRLEAEFPPHHSQSTFRKTSPAPGGPAGEGPLQSLTCLIGEKDLRLLEKLGDGSFGVVRRGEWDA-PSGKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFLLEAQPTDMRALQDFEEPDKLHIQMNDVITVIEGRAENYWWRGQNTRTLCVGPFPRNVVTSVAGLSAQDISQPLQNSFIHTGHGDSDPRHCWG----FPDRIDELYLGNPMDPPDLLSVELSTSRPPQHLGGVK----------------------------------------KPTYDPVSEDQDPLSSDFKRLGLRKPGLPRG--LWLAKPS-ARVPGTKASRGSGA----EVTLIDFGEEPVVPALRP------CAPSLAQLAMDACSLLDETPPQSPTRALPRPLHPTPVVDWDARPLPPPPAYDDVAQDEDDFEICSINSTLVGAGVPAGPSQGQTNYAFVPEQARPPPPLEDNLFLPPQGGGKPPSSAQTAEIFQALQQECMRQLQAPAGSPAPSPSPG-------GDDKPQVPPRVPIPPRPTRPHVQLSPAPPGEEE--TSQWPGPASPPRVPPREPLSPQGSRTPSP----------LVPPGSSPLPPRLSSSPGKTMPTTQSFASDPKYATPQVIQAPG----PRAGPCILPIVRDGKKVSSTHYYLLPERPSYLERYQRFLREAQSPEEPTPLPVPLLLPPPSTPAPAAPTATVRPMPQAALDPKANFSTNNSNPGARP---PPPRATARLPQRGCPGDGPEAGRPADKIQM--AMVHGVTTEECQAALQCHGWSVQRAAQYLKVEQLFGLGLRPRGECHKVLEMFDWNLEQAGCHLLGSWGPAHHKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PXR5-1", "uniprot_id": "A0A8M9PXR5_DANRE", "id": "A0A8M9PXR5-1", "name": "Activated CDC42 kinase 1", "aln": "MRRFDKLKKSFPFLAHFHVYRKLGSSMQCEEGTEWLLELLMEVQLQQYFLRIRDELNITRLSHFDYVKNEDLEKIGMGRPGQRRLWEAVKRRKTMCKRKSWMSKVFSGKRPEGDFNPQP-ASTFRKLSPTP--PLVDGQQQALTCLISEKDLALFEKLGDGSFGVVKRGEWFT-PNGKVLNVAVKCLKTDVLNQPDALDDFIREVNAMHSLDHQNLIRLYGVVLTHPMKMVTELAPLGSMLDRLRKTLGHFLISTLCQYTIQISNGMGYLESKRFIHRDLAARNILLASSEQVKIGDFGLMRALPKNDDHYVMQEHRKVPFAWCAPESLKTRTFSHATDTWMFGVTLWEMFTYGQEPWLGLNGSQILHKIDKEGERLPKPEDCPQDLYNVMMQCWAQKPDDRPTFVALREFLVETMPTDMRALQDFDEPDKLQIQMDDVITIIEGRAENYWWRGQNKRTLKVGQFPRNTVTSVAGLSAHDISRPLKNSFIHTGHGDTNPHRCWG----FPDRIDDLYLGNPMDPPDVLGLDLNSARPTQLPGRAKKEPPPRPPQPPLLVKSKCGPSVQFKHCSCPLCSLLAPLIKEPCYDAVAEDEEQTYSALRRLSLKKKGLKLKPAAWVSATR-LGDRSSYGARTPGGSTPTEVSLIDFGEEYPSATSSPSPVAEIQIPTLAKLALDAENILDRTPPQSPSRTLPRPLHPTPVVDWDARPLPPPPAYDDVAQDEDDFEVSSINSAERADGEPCSP------HAPCTPTGESKPHVEDNLFLPCRLSN-ACTFSQSAEIFQELQQECMRHLKVPVNSTSPGLEPHRQIVLTFSEDKPQIPPRIPIPPRPVKRAGGDYSRLSGDLSPVFGNEDDKERPPQIPPRDPFSQPGSRTPSPHVGSPQTRSSLCSAASIYGSSYLSTSPAKLMPTTQSFASDPKYAAPKVIQAQGKDKEPTKGPCILPIVRDGKKVSNTHYYLLPERPPYLDRYDKFFREAECGEE----------------KKQVNTATVKPMVHQHGELKSNFSSNNNSSLTASGFRGGLKSSFSLCRVSSDGSFNKADSNHDRVRLVQEAVHGVTIEECLTALQNHSWNVQKAVHYLKVEQLFCLGLKTRLECQQILEMYDWNLELASTQMLDSYGSVKLRR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VZI2-1", "uniprot_id": "ACK_DROME", "id": "Q9VZI2-1", "name": "Activated Cdc42 kinase Ack", "aln": "------------------MTSTSAVDGGLGSETAWLEDLLREVQLEQFLDRIRDDLQVTRLAHFDYVLPDDLERCGLGKPAIRRLMEAVRKKKAHQWRKNILSKLIGGGKQPS-----------SKKQSSAARESSQGNGTQLTCLIHEKDITMGLKLGDGSFGVVRRGEWSASPAGKVIPVAVKVLKSDNLTQPGIIDDFFREVQAMHALDHANLVRLYGVVLSQPMMMITELAERGSLLDTLRKQCRHTSLTIIWNWSVQIVTGMAYLEQKRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDDCYVMSEHKKVPFPWCAPESLRFRQFSHASDTWMFGVTLWEMFSFGEDPWVGLNGSQILRKIDREGERLHQPDACPPDVYAMMLQCWDKTPAERPTFAALKEYLASMSPPVMRASRSHHESKGLQIEPGDTIAIIDGRHELKLIKGQNQRTFDIGIFPRNLLEQRKVGAAGDVVMRSS---VGNGSSSSPFGFCWGGAAAMANGDDRQRKCASMTNQPHAKERKSTSSKQFAYNKLVNDSATGLQRR----------------------------NAVKHKGVVVGPQRPPPPQFQQEGILIDISPDMRPIAEAGTGGAKGAGDSSSLQADSSFCILDAPIDVPTYAGSSGSGDLNVSPTYYNEQPQFDFDPAKMTASPGRLQPPPYQMPPTYSNTMEFVQKRDLHQQQLATPVR-ERDPFDTTNVETTVALYSNFNQS----LEAASPPAPIYNSPSVRKSLFGGSKSNKENIPALESAAMQLNLSNLTLERHDATCIQPVEPVPAPPGDGVLLDKSFIAELEKDMYSNGQNRAQEEYQRNSTQMYASKDMVYKQNLTPLKNGAAPGSVHSNHSSPSSTASPKQ----NNVEAAAAAAATTQSVVNRIWYEQVASTQSEYYAQPPTEQAEEQIYQNHRHQQQQQQELNHSFVAISNRVVAPKNNAYSSTASLYDAVAASTAGSTYYGQVPNGSGAVLYDEVTQDDYLRPTRPAPLAPPP-LSAQQIQRRMEKMRLQQQQQLDGAHQLYAPVPSDYGREQEKLQQLMQELGSSAVEQDVRNALRAASGDVGLATRHYKIDQLARLGVAGRPQCEQALQQTNWSLEVAAELLLNAG-------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * ** :** ****:*:: *:**:*::***:**:** :***: *:*:*. *** ***:::*: **. :**::.* : . * ..:. :* ***** ***: : **********:**** : * **.: **** **.* *.** :***:***:***:*** **:*******: ** *:**** **:** *** * : : .:::*: **.***.***:*****.**:***: : :************::*. ***.**:****.*******: * ****:*************::*::**:********:***:***** :*: ** *:* :*:*** :.* :****.**:::* . *. *** :...*.. *:*: .*.*::*:** * :*** **: :* **** : . :* *: . : .* ..: *** :.: * .* .:: . . * . ::: .: : . . . ... : **. . .:: :*. .: . .*. * :...: : * * * :.* *: .:::: . . * . * :...** : . . ::* : *.: :.: ... . . ... : . : * : . . :**. .: . .: : : :.. ** * . ** : *: :: : *:. .* . . : * . . ::* . :*::: . : : . . . :: ... :: **: . .: *.:: *::** **: * :*.: *: :*.** *. :*.: ", "identical_positions": 292, "similar_positions": 265, "identity": "25.39%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-166", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7F9W0-1", "uniprot_id": "F7F9W0_RAT", "id": "F7F9W0-1", "name": "RING finger protein 37", "aln": "--MVINLCLPQFRPRIHCNKVSADGYEVENLISEDLIKRSHGFRTEYFIRPPIYVTVSFPFNVEICRVNIDLTAGGCQNVTGLELYTSALSSRAPQDAQDCWTTGLSETSVPDKEAFTLVGKVLLKNQNHVVFSHRGFKARPPFSPMEVTLLSPAVVAQDLWNKGAFSLSHVAHLKIGITHVTGSGISCIKRLEVWGQPARTCSQEVINSILSTASESPSQDLGLHTPALPMESDYDPGGQSEGQQSPCTLQDMSEVVQDVPEEFLDPITLEIMPCPMLLPSGKVIDQSTLEKCNLSEAAWGRVPSDPFTGLAFTPQSQPLPHPSLKARIDRFLLQHSISGCHLLGRAQTASAMTPSIITLPSRKRKTGQAEHSS-DYSLGMKASS-SATSPLLSPTTSEPTAKKMKGASELGLTDMDCSAGPVSHEQKLSQSLEIALTSTLGSMPSFTARLTKGQLQ-LGTRGSSACRRPATSSELPRSA-GPECASCRRVFSSYTTNEPVYQLPCGHLLCRPCLSEKQRSQP----MMCTACQQPVTSQDVLRVHF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q925F4-1", "uniprot_id": "RNF37_MOUSE", "id": "Q925F4-1", "name": "RING finger protein 37", "aln": "--MVVNLCLPQFRPRIHCNKVSADGYEVENLISEDLIKRSHGFRTEYFIRPPIYVTVSFPFNVEICRVNIDLTTGGYQNVSGLELYTSALSSRVSQDAQDCWTTGPVETSVPDKEAFTLVGKVLLKNQNHVVFSHRGFKARPPFSPMEVTLLSPAVVAQELWNKGALSLSHVAHLKIGITHVTGSGISCIKRLEVWGQPARTCSQEVINSVLLIASESLPQDLDLHAPALPMESDCDPGGQSESQHSPCTLQDMSEVESDVPEEFLDPITLEIMPCPMLLPSGKVIDQSTLEKCNLSEAAWGRVPSDPFTGLAFTPQSQPLPHPSLKARIDRFLLQHSISGCRLLGRAQTPSAMTPSVITLPSRKRKTEQAEHSS-HYSLGMSASS-SATSPLFSPTTSEPTAKKMKATSELGLTDMDCSAGPVSHEQKLAQSLEIALTSTLGSMPSFTARLTKGQLQ-LGTRGSSACRRPASSSEHPRSVSGPECASCKQAFSSYSTNEPVYQLPCGHLLCRPCLSEKQRSQP----MMCTACRQPVTSQDVLRVHF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O94941-1", "uniprot_id": "RNF37_HUMAN", "id": "O94941-1", "name": "RING finger protein 37", "aln": "--MVINLCLPQFRPRIHCNKISADGYEVENLISEDLTKRSHGFRTEYFIKPPVYVTVSFPFNVEICRINIDLTAGGGQNVTGLEMYTSASSSRVSWNTPQCRTLGPAEPSVPDKEAFTLVGKVLLKNQSQVVFSHRGFKARPPFGAMEATLPSPAVVAQELWNKGALSLSHVAHLRICITHVTGGGIPCIKRLEVWGQPAKTCSQEVIDSILLVTSENLPQDVALQAPALPMESDCDPGDQPESQQAPSSLQKLAEIIQDVPEEFLDPITLEIMPCPMLLPSGKVIDQSTLEKCNRSEATWGRVPSDPFTGVAFTPHSQPLPHPSLKARIDHFLLQHSIPGCHLLGRAQTALAVIPSSIVLPSQKRKIEQAEHVP-DSNFGVNASCFSATSPLVLPTTSEHTAKKMKATNEPSLTHMDCSTGPLSHEQKLSQSLEIALASTLGSMPSFTARLTRGQLQHLGTRGSNTSWRPGTGSEQPGSILGPECASCKRVFSPYFKKEPVYQLPCGHLLCRPCLGEKQRSLP----MTCTACQRPVASQDVLRVHF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P9U9-1", "uniprot_id": "A0A8M1P9U9_DANRE", "id": "A0A8M1P9U9-1", "name": "", "aln": "--MVFNLCLPHFQTSIHCNKLCADGYDVSNLLSEDLNVRRRGFKLEYFLRPPVHVTLNFQVQMEVCRLDVELWPWG---------MDQGRSSRR---------IEILTSSEKSGENFQLVSRCDLKEEIHLSFTHPFFKSRPPFCDPPPPFVG---ESKEFWSP--RSLSSVAQLRISIPYSGAASALGFRSLSIWALPSRCCSESELKKIHQAHLNTLKIN-----PTTPIAT------KSESFQTDS----------PTPEEFLDPLTQELMVLPMILPSGMIIDQSTLEEYEKREATWGRLPNDPFTGVPFTPSSKPLPNPLLKSRIDRLLLQTGHT--AVGSRNNTLNKPQPSRLMSHSVTDSNETHRMQS-ERVLETQRQRCSAKRKREFSSPSTSADADHPPLRKTLHTHTESDS----HERRLADSLDQALNAALDGLPVFTTQ----------SRSTADIENTSTG--------GQTCVFCSCSLTVYSSSVPSYSLPCDHLLCGPCLRHRNTSDPQKTTINCPACGSSASSRDITRVHH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VA79-1", "uniprot_id": "Q9VA79_DROME", "id": "Q9VA79-1", "name": "U-box domain-containing protein", "aln": "MSSLINFLNPKLKPSVETDAVCEDGYTAANLVADDVEQLERGFMCFAVCKPPIEIVFDFPKAVDMKVIKLWPSCGALR----------------------STAFELHGRHDGIWERVAFVRDLGRGVDSVTFCYQSDYNSRSSSNSEQS--------EKVFFFKSAHKILASTNSVKVVIRATERCPPVLRKVQMWGLPARSLDKADRELVKTIWSEISDPYGQRDAAQTPTGQRSPPRNVPELRDQST---------LSIPEEFLDSITWELMIFPTVLPSGKVVDQSTIDKHAEEEAKWGRQPSDPFTGLEFNAQRKAILHLALKARIEKFLMENSEHFKAVPRSLGTSRQRRRHASQFASSTCQPGQISPAAGTYSALSNAYKQQQRKSRATATATSSSAASFGGSPHSPPAAKRARHSQHGSACATVTSATTSIDQAIQQALQKVTRFSQLPSN--SSAGSGSSSAPPAS-----------CINCRSAQFGYEIR------TCRHLVCRECLVLLSQDQQ----CVCKVFFRCADVERYHKLDP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*: *:::. :. : :. *** . **:::*: :** . :**: :...* ::: :.: . * . :* : : :::*.. : :: .: :: : :: :.:*. *:: .: . : : . * .* . ******.:* *:* * :**** ::****::: ** *** *.*****: *.. :.: : **:**:::*:: . : * * . . . . . .:.: : . . : . * :: :: .:: : .: . :. * * * .* **:* ** . . * . . . ::. ", "identical_positions": 68, "similar_positions": 127, "identity": "12.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-17", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UHY8-1", "uniprot_id": "FEZ2_HUMAN", "id": "Q9UHY8-1", "name": "Fasciculation and elongation protein zeta-2", "aln": "MAA------DGDWQDFYEFQEPARSLLDQ--ENCNASPEPGAEAGAEAGGGADGFPAPACSLEEKLSLCFRPSDPGAEPPRTAVRPITERSLLQGDEIWNALTDNYGNVMPVDWKSSHTRTLHLLTLNLSEKGVSDSLLFDTSDDEELREQLDMHSIIVSCVNDEPLFTADQVIEEIEEMMQESPDPEDDETPTQSDRLSMLSQEIQTLKRSSTGSYEERVKRLSVSELNEILEEIETAIKEYSEELVQQLALRDELEFEKEVKNSFISVLIEVQNKQKEHKETAKKKKKLKNGS-SQNGKNERSHMPGT--------------------YLTTVIPYEKKNGPPSVEDLQILTKILRAMKEDSEKVPSLLTDYILKVLCPT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6TYB5-1", "uniprot_id": "FEZ2_MOUSE", "id": "Q6TYB5-1", "name": "Fasciculation and elongation protein zeta-2", "aln": "MAA------DGDWQDFYEFQEPAGSVQEQ--ENCNASPEAG--AGAHAGG--DSFPALASSLEEKLSLCFRPTS-EAEPPRAAVRPITECSLLQGDEIWNALTDNYGNVMPVDWKSSHTRTLHLLTLNLSEKGMNDGLLFDASDEEELREQLDMHSIIVSCVNEEPLFTADQVIEEIEEMMQESPDPEDDETPTQSDRLSMLSQEIQTLKRSSMSSYEERVKRLSVSELNELLEEIEAAIKQYSEELVQQLALRDELEFEKEVENSFISALIEVQNKQKEHKETAKKKKKLKSGS-SQNGRSERSHMPGT--------------------YLTTVIPYEKKSGPPSVEDLQILTKILHAMKEDSEKVPSLLTDYILKVLCPT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FBD4-1", "uniprot_id": "E7FBD4_DANRE", "id": "E7FBD4-1", "name": "", "aln": "MAEPSSRREDEEWQDFNEFKGGTGRNLDVSAEETRLSLLLLLDELSDAESALQTGAFTSTHFDENLQLCFQDVHSKTDAG-NELTSLNEETTLKCDEIWSALTDNYGHVMPVDWSQSRVRSLHLSTLSLDDRARLESVNLDVSDDEELRDQMDMHSIIVSCINEEPLLTAEQVIEEIEELMQESPEVESEQNVSHSG-VSFISQK----RSHSSQIYEDRVRLMSVLELNDELEDVETAIRGYSEELIHHLATRDELEFEKEVKNSFISVLIDVQNRQKLQREMLKKKRKVRSTSGSERLPSSRFSMEGISTAIQNGFRHTFGNGGGEKQYVTTVIPYERRDGPPSVQDLQIFTKILEAMRDDSDKVPSLLTDYILKVLCPT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * :**** **: : : *: . * :.* . : . : ::*:*.***: ::. : .:.* : *: ****.*******:******..*:.*:*** **.*.::. :.: :*.**:****:*:*********:*:***:**:********:*****: *.::. ::*. :*::**: : * **:**: :** ***: **::*:**: *****:::** **********:*****.**:***:** ::* ***:*::. * *:. ..* * * *:*******::.*****:****:****.**::**:*****************", "identical_positions": 181, "similar_positions": 99, "identity": "47.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-171", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D6Y9-1", "uniprot_id": "GLGB_MOUSE", "id": "Q9D6Y9-1", "name": "1,4-alpha-glucan-branching enzyme", "aln": "MAAPAAPAAGETGPDARLEAALADVPELARLLEIDPYLKPFAADFQRRYKKFSQVLHDIGENE-----GGIDKFSRG-YESFGIHRCSD-GGIYCKEWAPGAEGVFLTGEFSGWNPFSHPYK-KLEYGKWELYIPPKQNKSPLIPHGSKLKVVITSKSGEILYRISPWAKYVVR----ENNNVN--YDWIHWAPE--DPYKFKHSRPKKPR---SLRIYESHVGISSHEGKIASYKHFTSNVLPRIKDLGYNCIQLMAIMEHAYYASFGYQITSFFAASSRYGTPEELKELVDTAHSMGIVVLLDVVHSHASKNSEDGLNMFDGTDSCYFHSGP--RGTHDLWDSRLFIYSSWEVLRFLLSNIRWWLEEYCFDGFRFDGVTSMLYHHHGMGQG--FSGDYNEYFGLQ---VDEDALIYLMLANHLAHTLYP-DSITIAEDVSGMPALCSPTSQGGGGFDYRLAMAIPDKWIQLLKEFKDEDWNMGNIVYTLTNRRYLEKCVAYAESHDQALVGDKTLAFWLMDAEMYTNMSVLAPFTPVIDRGIQLHKMIRLITHGLGGEGYLNFMGNEFGHPEWLDFPRKGNNESYHYARRQFNLTDDDLLRYKFLNNFDRDMNRLEERCGWLSAPQAYVSEKHEANKTITFERAGLLFIFNFHPSKSYTDYRVGTATPGKFKIVLDSDAAEYGGHQRLDHNTNYFAEAFEHNGRPYSLLVYIPSRVALILQNVDLQN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LHH2-1", "uniprot_id": "A0ABK0LHH2_RAT", "id": "A0ABK0LHH2-1", "name": "1,4-alpha-glucan-branching enzyme", "aln": "MAAPAAPAAEEKGSEAQLKAALADVPELGRLLEIDPYLKPYAADFQRRYKKFNQVLHDIGENE-----GGIDKFSRG-YESFGIHRCSD-GGIYCKEWAPGAEGVFLTGEFSGWNPFSHPYK-KLEYGKWELYIPPKQNKSPPIPHGSKLKVVITSKSGEILYRISPWAKYVVR----ENNNVN--YDWIHWDPE--NPYKFRHSRPKKPR---SLRIYESHVGISSHEGKIASYKHFTSNVLPRIKDLGYNCIQLMAIMEHAYYASFGYQVTSFFAASSRYGTPEELKELVDTAHLMGIVVLLDVVHSHASKNSEDGLNMFDGTDSCYFHSGP--RGTHDLWDSRLFIYSSWEVLRFLLSNIRWWLEEYCFDGFRFDGVTSMLYHHHGMGQG--FSGDYSEYFGLQ---VDEDALVYLMLANHLTHTMYP-DSITIAEDVSGMPALCSPTSQGGGGFDYRLAMAIPDKWIQLLKEFKDEDWNMGNIVYTLTNRRHLEKCVAYAESHDQALVGDKTLAFWLMDAEMYTNMSVLAPFTPVIDRGIQLHKMIRLITHGLGGEGYLNFMGNEFGHPEWLDFPRKGNNESYHYARRQFNLTDDDLLRYKFLNNFDRDMNRLEETCGWLSAPQAYVSEKHEGNKTITFERAGLLFIFNFHPSKSYTDYRVGTAMPGKFKIVLDSDAAEYGGHQRLDHSTDYFAEAFEHNGRPYSLLVYIPSRVALILQNVDLPN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04446-1", "uniprot_id": "GLGB_HUMAN", "id": "Q04446-1", "name": "1,4-alpha-glucan-branching enzyme", "aln": "MAAPMTPAARPEDYEAALNAALADVPELARLLEIDPYLKPYAVDFQRRYKQFSQILKNIGENE-----GGIDKFSRG-YESFGVHRCAD-GGLYCKEWAPGAEGVFLTGDFNGWNPFSYPYK-KLDYGKWELYIPPKQNKSVLVPHGSKLKVVITSKSGEILYRISPWAKYVVR----EGDNVN--YDWIHWDPE--HSYEFKHSRPKKPR---SLRIYESHVGISSHEGKVASYKHFTCNVLPRIKGLGYNCIQLMAIMEHAYYASFGYQITSFFAASSRYGTPEELQELVDTAHSMGIIVLLDVVHSHASKNSADGLNMFDGTDSCYFHSGP--RGTHDLWDSRLFAYSSWEILRFLLSNIRWWLEEYRFDGFRFDGVTSMLYHHHGVGQG--FSGDYSEYFGLQ---VDEDALTYLMLANHLVHTLCP-DSITIAEDVSGMPALCSPISQGGGGFDYRLAMAIPDKWIQLLKEFKDEDWNMGDIVYTLTNRRYLEKCIAYAESHDQALVGDKSLAFWLMDAEMYTNMSVLTPFTPVIDRGIQLHKMIRLITHGLGGEGYLNFMGNEFGHPEWLDFPRKGNNESYHYARRQFHLTDDDLLRYKFLNNFDRDMNRLEERYGWLAAPQAYVSEKHEGNKIIAFERAGLLFIFNFHPSKSYTDYRVGTALPGKFKIVLDSDAAEYGGHQRLDHSTDFFSEAFEHNGRPYSLLVYIPSRVALILQNVDLPN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7Z8-1", "uniprot_id": "A0ACD6B7Z8_DANRE", "id": "A0ACD6B7Z8-1", "name": "1,4-alpha-glucan branching enzyme", "aln": "-----------------MDSSTDETLNLTAFLQTDPYIAHYEGELRRRYKQFAERLAQLEEAE-----GTFDRFTLS-YQSFGIQRRSN-NGLLFREWAPGAKAVFLTGDFNSWEKQSYPFT-QNEHGKWELYLPPKLDTSPAIEHLTKLKLVVLTKTGEYLFRISPWAKYVTK----TVDSVT--YDWTHWDPP--QPYQFQHPRPPRPS---SLRIYEAHVGISSPEEKIASYKNFTRDVLPRIKDLGYNCVQLMAIMEHAYYASFGYQVTNFFAASSRFGTPDDLKHLVDTAHSMGIAVLLDVVHSHASSNTEDGLNYFDGTDSCFFHGGS--RGKHSLWDSRLFNYSSWEVLRFLLSNLRWWMEEYRFDGFRFDGVTSMLYHHHGIDTS--FSGNYSEYFGMQ---VDENALIYLMLANHILHRLYP-QCITVAEDVSGMPGLCRAIEEGGLGFDYRLTMAVPDKWIQVLKEVRDEDWDLRNIVYTLINRRRGEASVTYAESHDQALVGDKSLAFWLMDKEMYTNMSALTTMTPVIDRGIQLHKLIRLLTHSLGGEGYLNFMGNEFGHPEWLDFPRKGNNESYYYARRQFNLVDTEHLRYRQLYAFDRDMNLTEDKYSWLTAAQAAVTTLNQDDKVIVFERANLLFIFNFHPCNSYTDYRVAAEHAGKYKIKLNSDEVQYGGHGRLLQDTEFFTEPMTFNGRDQSFQIYIPCRTALILANEDTDFRH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z992-1", "uniprot_id": "A1Z992_DROME", "id": "A1Z992-1", "name": "1,4-alpha-glucan branching enzyme", "aln": "---------------------MAEAKDIEKLFETDGYLRPFEHEIRRRHGVLEDWLNKINQSE-----GGLDGFSTA-YKHYGLHFQPD-NSVIAREWAPGARDVYLTGDFNNWHWESHPFK-KLDFGKWELHLPPNEDGSPAIKHLSEIKIIIRNHSGQLLDRLSPWAKYVVQPPKSANQGVN--YKQYVWEPPSYERYQRQHPGPPRPK---SLRIYECHVGIASQEPRVGSYDEFADRIVPRIKRQGYNCIQVMAIMEHAYYASFGYQVTSFYAASSRYGNPEQLKRMIDVAHSHGLFVLLDVVHSHASKNVQDGLNQFDGTNSCFFHDGA--RGEHSLWDSRLFNYVEYEVLRFLLSNLRWWHDEYNFDGYRFDGVTSMLYHSRGIGEG--FSGDYNEYFGLN---VDTDALNYLGLANHLLHTIDS-RIITIAEDVSGMPTLCRPVSEGGIGFDYRLGMAIPDKWIELLKEQSDDEWDMGNLVHTLTNRRWMENTVAYAESHDQALVGDKTIAFWLMDKEMYTHMSTLSDSSVIIDRGLALHKMIRLITHALGGEAYLNFMGNEFGHPEWLDFPRVGNNDSYHYARRQWNLVDDDLLKYKYLNEFDRAMNEAEERYGWLHSGPAWVSWKHEGDKIIAFERAGLVFVFNFHPQQSFTGYRVGTNWAGTYQAVLSSDDPLFGGHNRIDANCKHPSNPEGYAGRSNFIEVYTPSRTAVVYARVSD----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32775-1", "uniprot_id": "GLGB_YEAST", "id": "P32775-1", "name": "1,4-alpha-glucan-branching enzyme", "aln": "--------------------MYNIPDNVKGAVEFDPWLKPFADVLSERRYLADKWLYDITHATPDGSYQSLSKFARDSYKSYGLHANPETKEITYKEWAPNAERAFLVGDFNNWDTTSHELKNKDEFGNFTITLHPLPNGDFAIPHDSKIKVMFILPDGSKIFRLPAWITRATQPSKETSKQFGPAYEGRFWNPE--NPYKFVHPRPKFSESVDSLRIYEAHVGISSPEPKITTYKEFTEKVLPRIKYLGYDAIQLMAIMEHAYYASFGYQVTNFFAASSRFGTPEELKELIDTAHSMGILVLLDVVHSHASKNVEDGLNMFDGSDHQYFHSISSGRGEHPLWDSRLFNYGKFEVQRFLLANLAFYVDVYQFDGFRFDGVTSMLYVHHGVGAGGSFSGDYNEYLSRDRSFVDHEALAYLMLANDLVHEMLPNLAVTVAEDVSGYPTLCLPRSIGGTGFDYRLAMALPDMWIKLIKEKKDDEWEMGSIVYTLTNRRYGEKVVAYCESHDQALVGDKTLAFWLMDAAMYTDMTVLKEPSIVIDRGIALHKMIRLITHSLGGEAYLNFEGNEFGHPEWLDFPNVNNGDSYKYARRQFNLADDPLLRYQNLNEFDRSMQLCEKRHKWLNTKQAYVSLKHEGDKMIVFERNNLLFIFNFHPTNSYSDYRVGVEKAGTYHIVLNSDRAEFGGHNRINESSEFFTTDLEWNNRKNFLQVYIPSRVALVLALKE-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: .: * :: : : .* . * .: . :. *: *: :*:: .: : :****.*. .:*.*:*..*. *: . : :.*:: : : * : . : * :::*::. *. : *:..* . ..: . . *. * * . *: *. * . ******.****:* * :: :*..*: ::**** **:.:*:***************:*.*:*****:*.*::*:.::*.** *: ***********.* **** ***:: :**. . ** * ******* * .:*: ****:*: :: : * ***:********** :*:. . ***:*.**:. : ** :** ** ***.: * : . :*:****** * ** . . ** ****** **:** **:::** *::*:: .:*:** *** * ::*.***********::****** ***.*:.* : :****: ***:***:**.****.**** *************. .*.:** *****::*.* *:*: * *** *: *. ** : * *: :: :* *.*** .*:*:***** :*::.***.. .*.:: *.** :*** *: . .. : .* : :* *.*.*:: . ", "identical_positions": 290, "similar_positions": 198, "identity": "39.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-177", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R8U1-1", "uniprot_id": "DYH5_RAT", "id": "M0R8U1-1", "name": "Dynein axonemal heavy chain 5", "aln": "--------------------------------------------------------------------------------------------------------------------------MFRIGRRQLWKQSVTR---------VLTQRLKE--EKEAKRARLDGRHDYLFAIVASCLDLNKPEVEDALLEGNQIERIDQLFAVGGLRHLMFYYQDVEGAEAGQFGSSGGVNPASGKMKKP--------------------KVFVTEGKDVALMGACVFFTRADPSKAITAENIHREVSFNTLDTADGGLLNSVRRLLSDIFIPALRASSHGWGELEGLQDASSIQQEFLSSLEGFVGILSGAQNSLKEKVNLQKCDIVELKSLKEPMDYLALASNPETVEKVECCMRVWIKQMEQILAENNQLRKEADDVGPRAELEHWKKRLSKFNYLLDQLKSPDVKAVLAMLAAAKSKLLKVWRDADIRVTDAANEAKDNVKYLYTLEKCCDPLYSSDPVTMVDAIPTLINAIKMIYSISHYYNTSERITSLFVKVTNQMISACKAHITNNGTATIWSQPQDIVMQKIAAAIKLKQGYQCCFQETKQKLKQNPSEKQFDFSEMYIFGKFETFHQRLAKIMDIFTTFKTYSVLQDSKIEGLEDMVT---------KYQDVVAGIKKKEYNFLDQRKMDFDQDYDEFCKQTNELHSELQRFMDTTFEKIQSTRQALSTLKKFERLNIP--NLGIEAKYQIVFQNFGTDIDMISKLYTKQKYDPPLARDQPPIAGKILWARQLFHRLEQPMQLFQQHPFVLRTVEAKPVIRSYNRIAKVLLEFEVLYHRAWLQQIEEIHVGLEASLLVKAPGTGQLFVNFDPQILILFRETQCMSQMGLPVSPFAAALFEKRDMYKKNFSDMKMMLSEYQRVKLKMPPAIEQLMLPHLARVDEALQPGLAVLTWTSLNIGTYLENAFEKIKDLELLLDRINDLIEFRIHAILEEMSSVALCQLP-QDDPLTCEEFLQMTKDLCVNGAQKLHFKSSLVEEAVNELINMLL------------DVDVLPEEASEKVRHENAS--PNGDTSGGGEGCAEALAS---------------SFNAGTSSLPLTTIARKKK---EMEVL-EEARELLSYFNHQNTDALLKVTRNTLEAIRRRIHFSHMINFRDSKGASKVKQNH--LPIFRASVTLAIPNISMTPALEDIQQTLNKAVECIISVPKGVRQWSSELLSKRKMRERKMAAVQSN----EDSDSDTEVEESELQETLEL-ASVNLPIPVQTQNYYKNISDNKEIVKLVSVLSTVISSTKKEVITSMDRFKCYNHIWQKEKEDTIMTFIAQNPLLSEFESRILYFQSLEQEINAEPEYICVG-SIALYTADLKFSLTAETKAWMMVLGRHCNRKYRSEMENIFTVVEEFQKKLNRPIKDLDDIRIAMAALKEIREQQISTDFQVGPIEESYALLNKYGLLVAKEEMDKVDTLRYAWEKLLARASDVQNELGALQPSFRKELISTVEVFLQDCQQFYLDYDLNGPMVSGLKPQEASDRLIIFQNQFDNIYRKYITYTGGEELFGLPVTQYPQLLEIKKQLNLLQKIYSLYNNVIETVNSYQDTLWSEVNIEKINSELLEFQNRCRKLPRALKDWQAFLDMKKTIDDFSECCPLLEYMASNAMVERHWQRITTLTGHSLDVGNETFKLRNIMEVPLLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTLTFSSFKTRGELLLRGDSTSEVIASMEDSLMLLGSLLSNRYNMPFKAQIQNWVQCLSNSTDIIENWMTVQNLWIYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEIPNVVQCCVGDETMGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKTVKFHDKIYDRILSISSREGETIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQESGFQLIEFLSSFPAQVGLLGIQMLWTRDSEEALQNAKFDKKIMQKTNQSFLELLNMLIEMTTKDLSSMERVKYETLITIHVHQRDIFDDLCHMHVKSPTDFEWLKQCRFYFKEDSDKTMIHITDVAFTYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVLARKFFTLYQLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRASHTDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELETAISKQVEEAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGSGKTSCIHTLMKAMTDCGKPHREMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLKAKKGEHIWIVLDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKIVFEPHNIDNASPATVSRNGMVFMSSSVLDWSPILEGFLKRRSPQEAEILRQLYAETFPDLYRFSIQNLEFKMEILEAFVITQSTHMLQGLIPTK--------------------------------------------------EQAGDVDPEHLGRLFVFAMMWSVGAVLELEGRRRMELWLRSREGPTLHLP-QLTDPGDTMFDYYVAPDGTWRHWSMCIPEYVYPPDTTPEYGSILVPNVDNVRTDFLIKTIAKQGKAVLLIGEQGTAKTVIIKGFMSKFDPESHTVKNLNFSSATTPLMFQRTIESYVDKRMGTTYGPPAGKKMAVFIDDLNMPVINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSDASMDKIFGVIGEGYYCAQRGFSKEVQDAVIKLVPLTRRLWQMTKLKMLPTPAKFHYVFNLRDLSRIWQGMLNITSEVIKDTDELLRLWKHECKRVIADRFSMSSDVTWFDKAVVSLVEEEFGEEKTPVVDCGVDAYFVDFLRDAPEATGETPEETDAEMPKLYEPIASLNHLQERLSVFLQLYNESIRGTGMDMVFFRDAMVHLVKISRVIRTPRGNALLVGVGGSGKQSLTRLASFIAGYTSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKEESFLEYMNNVLSSGEVSNLFARDEIDEINSDLTSIMKKEHPKRPPTNDNLYEYFMSRVRGNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLSSYNIDCTAEIKKELVQCMGSFQDGVAEKCADYFQRFRRSTHVTPKSYLSFIQGYKFIYEEKHVEVQSLANRMNTGLEKLKEASESVAALSQELAVKEKELQVANEKADMVLKEVTMKAQAAEKVKAEVQKVKDKAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIKPSDIATVRTLGRPPHLIMRIMDCVLLLFHRRVNAVKIDLDKSCTVPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLSPYFEMSDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLIVQENRHALAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VHE6-1", "uniprot_id": "DYH5_MOUSE", "id": "Q8VHE6-1", "name": "Dynein axonemal heavy chain 5", "aln": "--------------------------------------------------------------------------------------------------------------------------MFRIGRRQLWKQSVTR---------VLTQRLKE--EKEAKRARLDGRHDYLFAIVASCLDLNKPEVEDALLEGNQIERMDQLFAVGGLRHLMFYYQDVEGAEAGHCGSSGGVNPASGKMKKP--------------------KVFVTEGKDVALMGACVFFIRSDPSKAITPENIHREVSFNTLDTADGGLLNSVRRLLSDIFIPALRASSHGWGELEGLQDASSIRQEFLSSLEGFVGILSGAQNSLKEKVNLQKCDIIELKSLKEPTDYLALASNPETVEKVECCMRVWIKQMEQILAENSQLRKEADDVGPRAELEHWKQRLSRFNYLLDQLKSPDVKAALALLAAAKSKLLKVWRDTDIRITDAANEAKDNVKYLYTLEKCCDPLYSSDPVTMIDAIPTLINAIKMVYSISHYYNTSEKITSLFVKVTNQMISACKAHITNNGTATIWSQPQEIVMQKIAAVIKLKQGYQSCFQETKQKLKQNPSEKQFDFSEMYIFGKFETFHRRLAKIMDIFTTFKTYSVLQDSKIEGLEDMAT---------KYQDIVAAIKKKEYNFLDQREMDFDQDYEEFCKRINELHNDLQRFMDITFEKIPSTRQALSTLKKFERLNIP--NLGIEEKYQIIFQNFATDIDTISKLYTKQKYDPPLARNQPPIAGKILWARQLFHRLEQPMQLFQQHPFVLRTAEAKPVIRSYNRIAKVLLEFEVLYHRAWLQQIEEIHAGLEASLLVKAPGTGELFVNFDPQILVLFRETQCMSQLGLPVSPFAAALFQKRDMFKKNFSDMKMMLSEYERVKLKMPPAIEQLMFPHLARVDEALQPGLAVLTWTSLNIGGYLENAFAKIKDLELLLDRVNDLIEFRIHAILEEMSSMALCQLP-QDDPLTCEEFLQMTKDLCVSGAQLLHFKSSLVEEAVNELINMLL------------DVDVPPEEAAENVCHENAS--PSGNTSGRREGHSEALAS---------------SFNAGASSLPLTATARKKK---ETEVL-EEARELLSHFNHQNTDALLKVTRNTLEAIRRRIHFSHMINFRDSNDASKAKQNH--LPIFRASVTLAIPNIAMTPALEDIQQTLNKAVECIISVPKGVRQWSSELLSKRKMHERKMAAVKNN----EDSDSDAEVEENELQETLEI-ASINLPIPVQTQNYYKNISDNKEIVKLVSVLSTVISSTKKEVITSMDRFKRYNHIWQKEKEDTIMTFIAQNPLLPEFESRILYFQSLEQEINAEPEYIRVG-SIALYTADLKLSLTAETKAWMAVIGRHCNRKYRAEMENILTVVEESQKKLSRPIKDLDDIRIAMAALKEIREQQISTDFQVGPIEESYALLNKYGLLVAKEEMDKVDTLRYAWEKLLARASDVQNELGALQPSFRKELISTVEVFLQDCQQFYLDYDLNGPMASGLKPQEASGRLIIFQNQFDNIYRKYITYTGGEELFGLPVTPYPQLLEIKRQLNLLQKIYSLYNNVIETVNSYQDTLWSDVNIEKINNELLEFQNRCRKLPRALKDWQAFLDLKKTIDDFSECCPLLEYMASNAMVERHWQRITALTGHSLDVGNETFKLRNIMEAPLLKYKEEIEDICISAVKERDIEQKLRQVINEWDNKTLTFSGFKTRGELLLRGDSTSEVIASMEDSLMLLGSLLSNRYNMPFKAQIQKWVQCLSNSTDIIENWMTVQNLWIYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEIPNVVQCCVGDETMGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKTVKFHDKIYDRILSISSREGETIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQEPGFQLIEFLSSFPAQVGLLGIQMLWTRDSEEALRNAKFDKKIMQKTNQAFLELLNMLIEITTKDLSSMERVKYETLITIHVHQRDIFDDLCHMHVKSPTDFEWLKQCRFYFKEDSDKTMIHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVLARKFFTLYQLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRASPTDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELETAISKQVEEAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGSGKTTCIHTLMKAMTDCGKPHREMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLKAKKGEHIWIVLDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKIVFEPHNIDNASPATVSRNGMVFMSSSVLDWSPILEGFLKRRSPQEAEILRQLYAETFPDLYRFSIQNLEFKMEVLEAFVITQSTHMLQGLIPPK--------------------------------------------------EQAGEVDPEHLGRLFVFAMMWSVGAVLELEGRRRMELWLRSREGPTLHLP-QLTDAGDTMFDYYVAPNGTWRHWSLCTPEYVYPPDTTPEYGSILVPNVDNVRTDFLIKTIAKQGKAVLLIGEQGTAKTVIIKGFMSKFDPESHMVKNLNFSSATTPVMFQRTIESYVDKRMGTTYGPPAGKKMAVFIDDLNMPVINEWGDQVTNEIVRQLMEQSGFYNLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSDASMDKIFGVIGAGYYCAQRGFSEEVQDALIKLVPLTRRLWQMTKLKMLPTPAKFHYVFNLRDLSRIWQGMLNITSEVIKDTDELLRLWKHECKRVIADRFSMSSDVTWFDKAVVSLVEEEFGEEKAPVVDCGVDAYFVDFLRDAPEATGETPEEADAEMPKLYEPIASLNHLRERLSVFLQLYNESIRGTGMDMVFFIDAMVHLVKISRVIRTPRGNALLVGVGGSGKQSLTRLASFIAGYTSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKEESFLEYMNNVLSSGEVSNLFARDEIDEINSDLTPIMKKEHPRRPPTNDNLYEYFMSRVRGNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLSSYTIDCTAEIKKELVQCMGSFQDGVAEKCADYFQRFRRSTHVTPKSYLSFIQGYKFIYEEKHMEVQSLANRMNTGLEKLKEASESVAALSKELAGKEKELQVANEKADTVLKEVTMKAQAAEKVKAEVQKVKDKAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIKPSDIATVRTLGRPPHLIMRIMDCVLLLFQRRVNAVKIDVDKGCTMPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLNPYFEMSDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLIVQENRHILAMQDLQKAQAELDAKQAELDVVQAEYEQAMAEKQTLLEDADRCRHKMQTASTLISGLAGEKERWTEQSKEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLHD-WKKEMKARKIPFGNGLNLNEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIKNKESQNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLEKNFIKTGSTFKVKVGDKEVDVMDGFKLYITTKLPNPAYTPEISARTSIIDFTVTVKGLEDQLLGRVILTEKQELEKERTHLLEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIIVLSNTKKTAEEVTQKLEISGETEIQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTYEVFKYAARGLYEEHKFLFTLLLTLKIDIQRNLVKHEEFLTLIKGGASLDLKACPPKPSKWILDMTWLNLVELSKLKQFSDILDQISRNEKMWRVWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIMDSMGENYAEGVILDLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKIETRYVSMGQGQEVHARKLLHQTMANGGWVLLQNCHLGLDFLDELMDVVTETETVHDTFRLWITTEVHKQFPITLLQMSIKFANEPPQGLRAGLRRTYGGVSQDLLDVSVGAQWKPMLYAVAFLHSTVQERRKFGPLGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTVRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSENMFGPDFTFYQGYNIPKCSTVDGYLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDVLDTILGIQPKDSSGGGDETREAVVARLADDMLEKLPEDYSPFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAVDGTIIMSENLRDALDCMFDARIPARWKKASWVSSTLGFWFTELLERNCQFTSWVSNGRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVLCNEVTKFMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIRIFAENNTA-RDPRLYCCPIYKKPVRTDLNYIAAVDLKTAQAPEHWVLRGVALLCDVK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TE73-1", "uniprot_id": "DYH5_HUMAN", "id": "Q8TE73-1", "name": "Dynein axonemal heavy chain 5", "aln": "--------------------------------------------------------------------------------------------------------------------------MFRIGRRQLWKHSVTR---------VLTQRLKG--EKEAKRALLDARHNYLFAIVASCLDLNKTEVEDAILEGNQIERIDQLFAVGGLRHLMFYYQDVEEAETGQLGSLGGVNLVSGKIKKP--------------------KVFVTEGNDVALTGVCVFFIRTDPSKAITPDNIHQEVSFNMLDAADGGLLNSVRRLLSDIFIPALRATSHGWGELEGLQDAANIRQEFLSSLEGFVNVLSGAQESLKEKVNLRKCDILELKTLKEPTDYLTLANNPETLGKIEDCMKVWIKQTEQVLAENNQLLKEADDVGPRAELEHWKKRLSKFNYLLEQLKSPDVKAVLAVLAAAKSKLLKTWREMDIRITDATNEAKDNVKYLYTLEKCCDPLYSSDPLSMMDAIPTLINAIKMIYSISHYYNTSEKITSLFVKVTNQIISACKAYITNNGTASIWNQPQDVVEEKILSAIKLKQEYQLCFHKTKQKLKQNPNAKQFDFSEMYIFGKFETFHRRLAKIIDIFTTLKTYSVLQDSTIEGLEDMAT---------KYQGIVATIKKKEYNFLDQRKMDFDQDYEEFCKQTNDLHNELRKFMDVTFAKIQNTNQALRMLKKFERLNIP--NLGIDDKYQLILENYGADIDMISKLYTKQKYDPPLARNQPPIAGKILWARQLFHRIQQPMQLFQQHPAVLSTAEAKPIIRSYNRMAKVLLEFEVLFHRAWLRQIEEIHVGLEASLLVKAPGTGELFVNFDPQILILFRETECMAQMGLEVSPLATSLFQKRDRYKRNFSNMKMMLAEYQRVKSKIPAAIEQLIVPHLAKVDEALQPGLAALTWTSLNIEAYLENTFAKIKDLELLLDRVNDLIEFRIDAILEEMSSTPLCQLP-QEEPLTCEEFLQMTKDLCVNGAQILHFKSSLVEEAVNELVNMLL------------DVEVLSEEESEKISNENSVNYKNESSAKREEGNFDTLTS---------------SINARANALLLTTVTRKKK---ETEMLGEEARELLSHFNHQNMDALLKVTRNTLEAIRKRIHSSHTINFRDSNSASNMKQNS--LPIFRASVTLAIPNIVMAPALEDVQQTLNKAVECIISVPKGVRQWSSELLSKKKIQERKMAALQSN----EDSDSDVEMGENELQDTLEI-ASVNLPIPVQTKNYYKNVSENKEIVKLVSVLSTIINSTKKEVITSMDCFKRYNHIWQKGKEEAIKTFITQSPLLSEFESQILYFQNLEQEINAEPEYVCVG-SIALYTADLKFALTAETKAWMVVIGRHCNKKYRSEMENIFMLIEEFNKKLNRPIKDLDDIRIAMAALKEIREEQISIDFQVGPIEESYALLNRYGLLIAREEIDKVDTLHYAWEKLLARAGEVQNKLVSLQPSFKKELISAVEVFLQDCHQFYLDYDLNGPMASGLKPQEASDRLIMFQNQFDNIYRKYITYTGGEELFGLPATQYPQLLEIKKQLNLLQKIYTLYNSVIETVNSYYDILWSEVNIEKINNELLEFQNRCRKLPRALKDWQAFLDLKKIIDDFSECCPLLEYMASKAMMERHWERITTLTGHSLDVGNESFKLRNIMEAPLLKYKEEIEDICISAVKERDIEQKLKQVINEWDNKTFTFGSFKTRGELLLRGDSTSEIIANMEDSLMLLGSLLSNRYNMPFKAQIQKWVQYLSNSTDIIESWMTVQNLWIYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEVPSVVQCCVGDETLGQLLPHLLDQLEICQKSLTGYLEKKRLCFPRFFFVSDPALLEILGQASDSHTIQAHLLNVFDNIKSVKFHEKIYDRILSISSQEGETIELDKPVMAEGNVEVWLNSLLEESQSSLHLVIRQAAANIQETGFQLTEFLSSFPAQVGLLGIQMIWTRDSEEALRNAKFDKKIMQKTNQAFLELLNTLIDVTTRDLSSTERVKYETLITIHVHQRDIFDDLCHMHIKSPMDFEWLKQCRFYFNEDSDKMMIHITDVAFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQISIILTCKKEHKKSFIFTDGDNVTMNPEFGLFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNVVLARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPMDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPNILLDKAGYPELEAAISRQVEEAGLINHPPWKLKVIQLFETQRVRHGMMTLGPSGAGKTTCIHTLMRAMTDCGKPHREMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLRAKKGEHIWIILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPNCKIIFEPHNIDNASPATVSRNGMVFMSSSILDWSPILEGFLKKRSPQEAEILRQLYTESFPDLYRFCIQNLEYKMEVLEAFVITQSINMLQGLIPLK--------------------------------------------------EQGGEVSQAHLGRLFVFALLWSAGAALELDGRRRLELWLRSRPTGTLELP-PPAGPGDTAFDYYVAPDGTWTHWNTRTQEYLYPSDTTPEYGSILVPNVDNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIKGFMSKYDPECHMIKSLNFSSATTPLMFQRTIESYVDKRMGTTYGPPAGKKMTVFIDDVNMPIINEWGDQVTNEIVRQLMEQNGFYNLEKPGEFTSIVDIQFLAAMIHPGGGRNDIPQRLKRQFSIFNCTLPSEASVDKIFGVIGVGHYCTQRGFSEEVRDSVTKLVPLTRRLWQMTKIKMLPTPAKFHYVFNLRDLSRVWQGMLNTTSEVIKEPNDLLKLWKHECKRVIADRFTVSSDVTWFDKALVSLVEEEFGEEKKLLVDCGIDTYFVDFLRDAPEAAGETSEEADAETPKIYEPIESFSHLKERLNMFLQLYNESIRGAGMDMVFFADAMVHLVKISRVIRTPQGNALLVGVGGSGKQSLTRLASFIAGYVSFQITLTRSYNTSNLMEDLKVLYRTAGQQGKGITFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEINSDLASVMKKEFPRCLPTNENLHDYFMSRVRQNLHIVLCFSPVGEKFRNRALKFPALISGCTIDWFSRWPKDALVAVSEHFLTSYDIDCSLEIKKEVVQCMGSFQDGVAEKCVDYFQRFRRSTHVTPKSYLSFIQGYKFIYGEKHVEVRTLANRMNTGLEKLKEASESVAALSKELEAKEKELQVANDKADMVLKEVTMKAQAAEKVKAEVQKVKDRAQAIVDSISKDKAIAEEKLEAAKPALEEAEAALQTIRPSDIATVRTLGRPPHLIMRIMDCVLLLFQRKVSAVKIDLEKSCTMPSWQESLKLMTAGNFLQNLQQFPKDTINEEVIEFLSPYFEMPDYNIETAKRVCGNVAGLCSWTKAMASFFSINKEVLPLKANLVVQENRHLLAMQDLQKAQAELDDKQAELDVVQAEYEQAMTEKQTLLEDAERCRHKMQTASTLISGLAGEKERWTEQSQEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRDLLLND-WRKEMKARKIPFGKNLNLSEMLIDAPTISEWNLQGLPNDDLSIQNGIIVTKASRYPLLIDPQTQGKIWIKNKESRNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLERNFIKTGSTFKVKVGDKEVDVLDGFRLYITTKLPNPAYTPEISARTSIIDFTVTMKGLEDQLLGRVILTEKQELEKERTHLMEDVTANKRRMKELEDNLLYRLTSTQGSLVEDESLIVVLSNTKRTAEEVTQKLEISAETEVQINSAREEYRPVATRGSILYFLITEMRLVNEMYQTSLRQFLGLFDLSLARSVKSPITSKRIANIIEHMTYEVYKYAARGLYEEHKFLFTLLLTLKIDIQRNRVKHEEFLTLIKGGASLDLKACPPKPSKWILDITWLNLVELSKLRQFSDVLDQISRNEKMWKIWFDKENPEEEPLPNAYDKSLDCFRRLLLIRSWCPDRTIAQARKYIVDSMGEKYAEGVILDLEKTWEESDPRTPLICLLSMGSDPTDSIIALGKRLKIETRYVSMGQGQEVHARKLLQQTMANGGWALLQNCHLGLDFMDELMDIIIETELVHDAFRLWMTTEAHKQFPITLLQMSIKFANDPPQGLRAGLKRTYSGVSQDLLDVSSGSQWKPMLYAVAFLHSTVQERRKFGALGWNIPYEFNQADFNATVQFIQNHLDDMDVKKGVSWTTIRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSENMFGPDFSFYQGYNIPKCSTVDNYLQYIQSLPAYDSPEVFGLHPNADITYQSKLAKDVLDTILGIQPKDTSGGGDETREAVVARLADDMLEKLPPDYVPFEVKERLQKMGPFQPMNIFLRQEIDRMQRVLSLVRSTLTELKLAIDGTIIMSENLRDALDCMFDARIPAWWKKASWISSTLGFWFTELIERNSQFTSWVFNGRPHCFWMTGFFNPQGFLTAMRQEITRANKGWALDNMVLCNEVTKWMKDDISAPPTEGVYVYGLYLEGAGWDKRNMKLIESKPKVLFELMPVIRIYAENNTL-RDPRFYSCPIYKKPVRTDLNYIAAVDLRTAQTPEHWVLRGVALLCDVK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HIQ6-1", "uniprot_id": "A0AC58HIQ6_DANRE", "id": "A0AC58HIQ6-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------MALSYRSVKSNIRSRGTHQPSAPVDNIKEMQQKLKE--EREAKRAQLDSRHDYVLSIVSSCVGLEKSEVEDAILEGTQIERMEQFFAVDGLPHLILYYQDTEATEAAESSS-------ASRIKKA--------------------KVFVTEGTDVALTGICVFFTRANTSKPITSENIHRDVNFNMLDTTGVGLLKSVEQLLSEIFIPTLRKMNYGWGELASPQ-AQAVKQDFISSLDSFVSVLSGAQESLQEKVNLQECETFDLKTLKGPSDYTAVANSADALEKIEACMKTWIKQIEQVLAESDQLRKEADDLGPRAELDHWKKRMSRFNYLLDQLKSPEVKAVLGVLLVAKSKLIKVWRELDIRITDAANEAKDNVKYLYTLEKFCDPLYNSNPVSMVEAIPGLINAIRMIHSISRYYNTSEKITSLFVKVTNQMITACKAYITNNGSATIWDQPQEVVSEKLKAAIRLNQEYQKYFQKTKQKLEENPSERQFDFSEMYIFGKFDTFQRRLSKILNLFSTITTYNALQDSKIEGLETMATRFQTADMQGKWEAIVLTMKKKQYSFLDQRRTDFDQDYEEFCKQTSELHNQLKTFMDNTFDKIQNTERALYVLKKFERLGIP--DLGISDKYQRILQNFGRDIEMISRIYNKQKTDPPIAPDLPPTAGKILWARQLYSRIQEPMDLFQQLPGLLSTPDAKPIIRNYNRVAKVLLEFEVLYHHSWMAQTEAVKAGLQASLLVKSPETGQLFVNFDPQILTQIRETDCMLGMGLDIPPFAAILQQKKEVFKKNYNKLQLMVTRNSGVRSKIQAAFEQLLMPHVAKVDEAILPGLTSLNWTSLNIDKYLSRITAALDNLELLLHRVNDLVEFRIDAVLQEMSTAMLCVLP-EDEPCTCEEFVQTTKELCIKGAQMLHTKSSLVEEAANELINMLL------------ELEQKEEDDRNRDDSRTESKVEQMESDEEECKSEGRLFS---------------RSTMAPSLGPSSPLLRKKKKLDLMKVMEEEARELLSHFNHRNVDALLRLTRNTLETLRKRIHASSLMHFLAEADSPSRQKGSGPQPIFRAGVCLAIPNIIMVPGLDEVQHALNRAVDYVVSVSKGVGQWSKERISKRKMSERRMAALKQNSQESESEDADSTYHSFAEGSTSDISASANQAIPFQIKNYHKSISENKEIVKLVSVLSTSINSTKKEIMNALERFSMYHHIWKKDREETIQKFIQGNPFLSEFESQILYYRDLELEINAEPEFISVG-ALALYTVDLKLALTSETKSWMVDFGQYCNRKYRMEMEQIFTFIDEASKKLNRQIKDLDDIRIAMATLKEIREHQISIDFQVGPIEESYSMLHKYGLLIAKEEAEKVDTLRYTWEKLLSRSTEVQNELVSLQPKFRGELIKNVETFVEDCQHFYHDYDRDGPMVVGLAPQDASDRLIMFQNRFDNLFRKYITFTGGEELFGLPVTQHPQLLEIRKQLTLLQKLYGLYNSVIDTVNGYYDISWADIHIDRINNELLDFQARCRKLPRGLKEWQAFMDLKKTIDEFSECCPLLDLMTNKAMMTRHWKRITEVTGHTFEVETDNFKLRNIMEAPLLKYKEEIEDICISAVKERDIEQKLKQVIAEWDNKTFTFAQFKTRGELLLRGDSTSEIITNMEDSLMVLGSLMSNRYNTPFKAQIQKWVQNLSNTTDIIENWMTVQNLWIYLEAVFVGGDIAKQLPKEAKRFSNIDKSWVKIMTRAHEMPNVVQSCVGDETMGQLLPHLLEQLEMCQKSLTGYLEKKRLLFPRFFFVSDPALLEILGQASDSHTIQAHLLNIFDNIKCVRFHEKMYDKILAISSREGETIELDKPVIAEGNVEVWLNALLKESQRSLHLVIRQAALAIQDSGFELIEFLDSFPAQVGLLGIQMIWTKDSEDALSNARYDRKIMSKTNQFFLELLNNLIDMTTKDLGAVERTKYETLITIHVHQRDIFDDLCRLHIKSPTDFEWLKQCRFYFNEDSDKMMINITDVGFVYQNEFLGCTDRLVITPLTDRCYITLAQALGMSMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIDLPVLSVAAQQIAIVLTCKKERRKNFIFTDGDNVEMNPEFGIFLTMNPGYAGRQELPENLKINFRSVAMMVPDRQIIIRVKLASCGFIDNIELARKFFTLYKLCEEQLSKQVHYDFGLRNILSVLRTLGAAKRANPNDTESTIVMRVLRDMNLSKLIDEDEPLFLSLIEDLFPGIQLDKAGYPDLESAIDKQVTEAGLINHPPWRLKVIQLYETQRVRHGMMALGPSGAGKTTCIHTLMKAMTDCGQPHREMRMNPKAITAPQMFGRLDVATNDWTDGIFSTLWRKTLRAKKGEHIWIVLDGPVDAIWIENLNSVLDDNRTLTLANGDRIPMAPNCKIVFEPHNIENASPATVSRNGMVFMSSSVLNWSPILEGWLKNRSAQEGMVLKDLFSSSFPELYRFSIQSLQYKMEMLEAFIIMQCINMLQGLIQPK--------------------------------------------------EQGGELSREHMERLYVFALMWSVGALLELDDRMKLERWLRNHDSIHLDLPNIPPHSEDTMFDFYVTNDGHWVHWNTRVEEYIYPPDSTPEYGSILVPNVDNVRTDFLIQTIAKQGKAVLLIGEQGTAKTVIIKGYMSKYDPESHTAKSLNFSSATTPLMFQRSVESYVDKRMGTTYGPLAGKKMSIFIDDINMPVINEWGDQVTNEIVRQLMEQNGFFNLEKPGEFTNIVDIQFLAAMIHPGGGRNDVPQRLKRQFSIFNCTLPSNASIDKIFGVIGTGHYCSHRGFSEEVRNTVARLVPLTRRLWQMTKVKMLPTPANFHYIFNLRDLSRIWQGMLGVTAEVISTPQLLLQLWKHECKRVIADRFTAPEDVAWFDSTLAKLVEEQLGEEEREVVDLGVDSYFVDFLRDAPEATGDEPEETDFDMPKVYEPIESFDSLMERLNMFLSHFNESIRGASMDMVFFRDAMIHLIKISRIIRTPRGNALLVGVGGSGKQSLTRLASFIAGYKTFQITLTRSYNTANLMEDLKGLYRTAGQQGKGISFIFTDNEIKDESFLEYMNNVLSSGEVSNLFARDEIDEIISDLIPVMKREFPRRPPTNENLHEYFMSRVRQNLHVVLCFSPVGERFRNRALKFPALISGCTMDWFSRWPKDALIAVSEHFLSTYDIDCTLEVKSEVVQCMGSFQDGVAEKCADYFQRYRRSTHVTPKSYLSFIHDYKTIYKEKHSEVQTLADRMNTGLQKLKEASESVAALSKELEVKEKELQIANAKADMVLKEVTVKAQAAEKVKVEVQKVKDKAQAIVDSISADKAIAEEKLEAARPALEEAEAALQTIKPSDIATVRTLGRPPHLIMRIMDCVLLLFQRRVNTVKTDPEKNCTMPSWQESLKLMTAGNFLGSLQQFPKDTINEEVVEFLSPYFDMVDYNIETAKRVCGNVAGLCSWTKAMAAFFSINKEVLPLKANLAVQENRLTIANLDLQKAQAELDAKQAELDVVQAEYEKAMMEKQTLLEDAERCRHKMQTASSLISGLAGEKERWTQLSKEFAAQTKRLVGDVLLATAFLSYSGPFNQEFRNLLLTD-WQREMKFRQIPFRTNLNLTEMLIDAPTVSEWNLQGLPNDDLSIQNGIIVTKAARFPLLIDPQTQGKIWIKNKESKNELQITSLNHKYFRNHLEDSLSLGRPLLIEDVGEELDPALDNVLEKNFIKTGFTYKVKIGDKEVDVMKGFRLYVTTKLPNPAYTPEISARTSIIDFTVTMRGLEDQLLGRVILTEKQELEKERTDLLEDVTANKRKMKELEDNLLFRLTSTQGSLVDDESLITVLGNTKRTAEEVTQKLQIAAETEIQINAAREEYRPVATRGSILYFLITEMSMVNVMYQTSLRQFLGLFDLSLTKSSKSPITSKRIANIIEYMTFEVHKYAARGLYEEHKFLFTLLLTLKIDMQSNRVKHEEFLTLIKGGASLDLKACPPKAAKWILDITWLNLVELSKLWQFSDILDQIGRHEKQWRSWFDREAPEEEPIPNAYDQALDCFRRLLLIRSWCPDRTIAQARKYITQSMGERYAEGVILDLEKTWEESEPRTPLICFLSMGSDPTDSIIALGKRQRIETRYVSMGQGQEVHARKLLQHSMANGGWALLQNCHLGLDFMDELMDTITETDSVHDTFRLWMTTEVHKHFPITLLQMSIKFTNEPPQGLKAGLKRTYGGISQDLLDVSNMVQWRPMLYGVAFLHSTVQERRKYGPLGWNIPYEFNQADFNATIQFVQNHLDDIDIKKGVSWNTVRYMIGEIQYGGRVTDDYDKRLLNTFAKVWFSENMFSPDFHFYKGYSIPKCSNVDQYLQYIQGLPTYDTPEVFGLHPNADITYQSKLAKDVLDTILSIQPKDSSTGGGETREAIVGRLADDMLEKLPPDFVPFEVRERLMSMGPLQPMNIFLRQEIDRMQRVIVLVRNTLHDLKLAIDGTIIMSENLRDALDCMYDARIPARWKKASWASTTLGFWFTELLERNRQFHSWIFEGRPNCFWMTGFFNPQGFLTAMRQEITRANKGWALDRMVLCNEVTRWMKDDITQPPAEGVYVYGLYLEGAGWDRRNCKLIDSKPKVLFEMMPVIRMYAENNGV-KDARLYSSPIYKKPVRTDLNYIAAVDLRTSHPPEYWILRGVALLCDVK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "F1MAM6-1", "uniprot_id": "F1MAM6_RAT", "id": "F1MAM6-1", "name": "", "aln": "MESEEDNTAPPPLSEEEAPPPPPSEDTAPPAEQAPPPEDGAPPPTGDGVEPSAEGEALQAEGIDPASLSVQEDPALNMTDYRSLIPSDEEITMPPEDDESGQGRVRARLAPRPVQSVLSDGLSQSSRRSSKFRRSMTGIPNLQETLKEKQARFRE--AREGRRMKIDPSYKYIFEILGEKLGLDLVSVEELILDCPSLDAFSSFFEKGGSKTLKFLYQEGD-VPGLECGRTITGVPKGGKMMR----------------------LYIDNAAPEKLKELCLFFVRCRNDVAINSKTIYEDVLFTVLDASKG-LLKGIKNMLKNIFLPAILATGN-WGALNQSKQGESEKHIFTETINRYLLFLDGATISIEGTVMLKKVDNIDFSKLHTFEEVTAAASSSEMVHQLEDVLMMWYKQIEQVLIESEQMRKEADDSGPLTELEHWKRMSAKFNYIIEQIKGPSCKAVINVLNVAHSKLLKNWRDLDARITDTANESKDNVRYLYTLEKVCQPLYNYDLVSMAHGIQNLINAIRMIHSVSRYYNTSERMTSLFIKVTNQMVTACKAYITDGGTNHVWDQETPAVLKKIQDCIFLFKEYQASFHKTRKQILESSGEKSFEVSEMYIFGKFEAFCKRLEKITEMITIVQTYSALSNSTIEGIDILGI---------KFKNIYQGIKKNQYDILDPRRTEFDTDFSDFMGKINTLEIQIQAFMNITFGKILSSQQALQLLQRFQKLNMPCLQLEINHTIERILQCYVAELEATKKLYHSQKDDPPLARNMPPIAGKILWVRQLYRRINEPINYFFKNSDILSSIEGKAVIRQYNKISYVLVEFEVVYHTAWVKEISQLQYALQATLFVRHPETGKLLVNFDPKILEVVRETKCMIKMKLDVPEQAKKLLKLESKLKADKLYLQGLLQYYDDLCQEVPSVFVNLMTPKMKKVESVLRQGLTVLTWSSLMLESFFKEVESVLDMFNQLLKKVNDLCEMHIDTVLKEIAKTLLISLS-DSGATRVEDMLTLNETYTKEWADILNHKSRHVEEAVKELILIFE------------QIYEVKYTGKPAKP-------VPEQRKHVVFGSEADEGE---------------SLEYDPDSTARDVDNNDKE-----DEFKKECKEVYAFFSHQLLDSLQKATRLSLDTMKKRIFVGNQGRKRSEDVVS----------FIKTEVHLAIPNVVMVPSLDDIQQAINRMIQLTLEVSRGVAHWGQQQVRRTKSPQ------TSS----RGSDQPSIMGKALKKEERSFEESIP---ARKLKNFYPGVAEHKDISKLVLLLSSSVNSLRKAATEALQDFQKYKTLWTEDRDVKVKEFLANNPSLTEIRSEILHYATFEQEIEELKPIIDVG-ALELHTEPMKLALSIEAKAWKMLLCRYLNEEYKKKMSDMIVFINEYLKKLSRPIRDLDDVRFAMEALSCIRDNEIQMDMTLGPIEEAYGILNRFEVEVTKEESEGVDTLRYSFNKLQSKAVSVQDELVQVQPKFKSSLLESVDVFREDVINFTEAYETEGPMVPNIPPQEASNRLQIFQANFDDLWRKFVTYSAGEQLFGLPVTDYEVLHKTRKELNLLQKLYGLYDTVMGSISGYYEILWGDVDIEKINAELLEFQNRCRKLPKGLKDWQAYLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDTFCLRNIMEAPLLKNKDDIEDICISAIKEKDIEAKMTQVIENWTNQNLSFSAFKGKGELLLKGTESGEIITLMEDSLMVLGSLLSNRYNTPFKKTIQNWVYKLSTSSDIIEEWLVVQNLWVYLEAVFVGGDIAKQLPQEAKRFQNIDKSWVKIMQRAHENPNVISCCVGDETMGQLLPHLHEQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVTFHPKDYDRMTAVISREGEKIMLDTPVMAKGPVEIWLLDLLKVQMSSLHNIIRSAFYQISDSGFLLLPFLNHFPAQVGLLGIQMLWTHDSEEALNSAKDDRKIMHITNQKFLDILNTLISQTTHDLTKFDRVKFETLITIHVHQRDIFDDLVKMHIKSVTDFEWLKQSRFYFKEDLDQTVVSITDVDFNYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDMGRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVLTARKERKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQIIMRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARPEDSELSTVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSNTYAELQAAVDNQVNLEGLINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKSLTECGRPHREMRMNPKAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNSVLDDNKTLTLANGDRIPMAPTCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWLKRRTQQEATAFLSLYDKVFEDAYTYMKLNLIPKMQLLECNYITQSLNLLEGLIPSK--------------------------------------------------EEGGVSSVDHLHKLFVFGLMWSLGALLELESREKLEVFLRGHES-KLNLPEIAKDSHHTMYEFYVTDYGDWEHWNKRLQPYFYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQHKAVLLTGEQGTAKTVMVKAYLKKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRMGSTYGPPGGRKMTVFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQLIAAMIHPGGGRNDIPQRLKRQFTVFNCTLPSNTSIDKIFGIIGCGYFDPCRKFRPEICDMIGNLVSVGRVLWQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTIKAEECKTIPILMALFKHECNRVIADRFITPDDEQWFNTQLIRAVEENISPEVAASINP--EPYFVDFLRDMPEPTGDEPEDTMFEVPKIYELVPSFEFLCEKLQFYQKQFNEIIRGTSLDLVFFKDAMTHLIKISRIIRTSCGNALLVGVGGSGKQSLSRLASFIAGYQIFQITLTRSYNVSNLIDDLKNLYKVAGADGKGITFIFTDNEIKDEAFLEYLNNLLSSGEISNLFARDELDEITQGLISVMKRELPRHPPTFDNLYEYFISRSRRNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPKEALIAVASYFLSDYNIVCSMEIKRHVVEAMGLFHDMVSESCENYFQRYRRRAHVTPKSYLSFINGYKNIYTEKVKYINEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASVKADEVLAEVTVSAQASAKVKNEVQEVKDKAQKIVDEIDSEKVKAESKLEAAKPALEEAEAALNTIKPNDIATVRKLAKPPHLIMRIMDCVLLLFQKKIDPVTMDPEKPCCKPSWGESLKLMSATGFLFSLQQFPKDTINEETVELLQPYFNMDDYTYESAKKVCGNVAGLLSWTLAMAIFYGINREVLPLKANLAKQEGRLAVANAELGKAQALLDEKQAELDKVQAKFDAAMNEKMDLLNDADMCRKKMQAASTLIDGLSGEKVRWTQQSKEFKAQINRLVGDVLLCTGFLSYLGPFNQIFRNYLLKDQWELEMKARKIPFTENLNLIAMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWIKSKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIREELDPALDNVLEKNFIKSGTAFKVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILTEKQELESERVKLLEDVTFNKRKMKELEDNLLYKLSTTQGSLVDDESLIGVLRITKQTAAEVSEKLHVAAETEIKINTAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQSMARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFALLMTLKIDLQRGTVKHKEFQALIKGGAALDLKACPPKPFRWILDMTWLNLVELSKLPQFAEIMNQISRNEKGWKNWFDKDAPEEEIIPDGYNDSLDTCRKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEKTWEESDTHTPLICFLSMGSDPTIQIDALAKKLKLECRTISMGQGQEVHARKLVQLSMQQGGWVLLQNCHLGLEFMEELLETLMVTETTEDSFRVWITTEPHDRFPITLLQTSLKFTNEPPQGVRAGLKRTFAGINQDLLDISNLPMWKPMLYTVAFLHSTVQERRKFGPLGWNIPYEFNSADFSASVQFIQNHLDECDIKKGVSWSTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSEKMFEPSFCFYTGYKIPVCKTLDQYFEYIQSLPSLDNPEVFGLHPNADITYQSNTASDVLETITNIQPKESGGGMGETREAIVYRLSEDMLSKLPPNYVAHEVKARLMKMGHLNSMNIFLRQEIDRMQRVISLLRNSLNDLKLAIEGTIIMSENLRDALDNMYDARIPQLWKRVSWDSSTLGFWFTELLERNAQFSTWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDSVTIHNEVLRQTKEEIITPPVEGVYIYGLYMDGASWDRRNGKLTESTPKVLFMQLPVLHIYAINSTAPKDPKLYVCPIYKKPRRTDLTFITVVYLRTVLSPDHWILRGVALLCDIK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0B4LH20-1", "uniprot_id": "A0A0B4LH20_DROME", "id": "A0A0B4LH20-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------MFVQKKKLVEHVLAMRAEGGSSDDDDEEEDQGDILQRRREECERKARRGEMDPRLEFTFQLLIDATQLPRHQLMDYIFEGDMLDEINQLFLPNMKNKLLWFYQETDDPEPTPVPDPNKPGPSRSGVASSSSKTPQGGASPSGMPPPKHKKLFLTDGWTCAFTGVCIYIFRVNTSKQLPEEGFQKDLYCGVIDAKNIGLVTSIERIVEFVFMQALAFPSLEGDEE--DVSCGLIKGQLLPGLRSFCSALR-VCEQVCDHHNVFADGCDMFEKIDAVEEVKDMSKNQEFCAQLEERVNNWTKGILKILGESEQLRKENDHSGPQDELEYWKKRGAQFSQLLAHLQDKEVQFTLHCLFLAGSRIIKQWKETDRKITFCYNEARDNSKFIQAMETCCHSLYLDDPVSMKESILSLLQTVRLIYSVSQFYNTSERTSALMVKITNQMIETCKSYITCRCKETIWSQDRNVIRTKLSNCIKLNHIYHETYYTVREQP-FLPNQTPFGFSENFVFGKFDTFCERLSKIISMFNLIDDYNHLFERRLEGLLLGEALEDASN---HFEEAKKEVTSRKYDYLDHRNSDFNIDFERFIHKTNSLKDTIATLIEKDFDTVWETPQCIRFLVRFEKVSEKIPLTRMDEKYTRILRYVEKEVDRILKTFRKQRDDPPLARNFPPIAGRIHWCRALSLHITELMDAVMEHVVLSSLPMAKDLDVRYHNVLGILQEYEDEIVSIWLDQDVSVADACLLQPLLSLQGD-KLFVNLHPTIPLLIREAKMLAKLDIELPIVAATLMSRQQYFITIQDSLNCLIKMFLSTVRAVKLEVRPLFLPQLVRLTAMLKPGLHTINWTNQNWTEFYERCKQAIESFDVLVARVHDIYSNRILHVLMWMQDVSLQILPADDEIWTVDEFLERSEEACRKAAIELNRKSQMVSEAVEEVLSLVDRATAAFKEIAGDDVITLFDAATPKGDNSGSGGRKPEDGGGGGGGAAAPSTSGGGGGGQQQDWSILWSCFENPLSLLSTTESLPKG---MQDMVCNAVVEMRRYYSRKVIDVLIKVIRAALDTLRRRFIADENETVFKK-------------PVFALHAQLQIPHVVIKPNLDELQDILVTAGKNITGIAKGVAQWS----SGKDPPQVSMTVQPRVG---RNHNESTGGGKSRRRKIYCLASEERPQMPHMLKSFYSAIMDNKEVAKAVNQLASCTKNVKPEIQTYIKRWKPYHFLWKNDR--TTRQLMEFG--LQEFETTLRCLSDLDANLLVEPDMEVFGQCVAVYNEKLKYGLAIEIKSCNHKIGQAMKKKYKKEMDYVYAVINEMDRKLDRPIRDLDDVRMIMETLGKIREQEVDMELRIDPIEEAFNVLTRYEVQVEREQFDLVDNLRATFQNLLAGALQAQVKLLDMQPAFQDDLRTNLDNFKQDKISYVTEYRTAGPMQAGLTPREASDRLILFQNRFEGMWRRLQTYQSGEELFGLPQTDYPELGQIRKELNLLQKLYKLYNDVIDRVSSYYDIPWNEVDIEEINNELMEFQNRCRKLPKGLKEWPAFHALKKTIDDFNDMCPLLELMANKAMKPRHWQRIMDVTRYIFEFDSEGFSLKNILEAPLLKHKEDIEDICISAMKEKDIEAKLKQVTNEWSVHELQFMSFNNRGELLLRGDTTAETIGQLEDSLMVLGSLLSNRYNAPFRKQIQQWVYDLSNSNEILERWLLVQNMWVYLEAVFVGGDIAKQLPKEAKRFSKIDKSWQKIMQRAHETPGVVACCVGDDLLKQLLPHLQEQLEICQKSLSGYLERKRMMFPRFFFVSDPALLEILGQASDSHTIQNHLLNIFDNTKSVKFHDVEYNKMMAIISSEGEMIQLDRAIRAEGSVETWLTQLLVTAQASLHSIIRTAYATINDPNFTLLSFLEKAPAQIGLLGIQMVWTRDAEMALMRGR-ERKVMMETNNKFLEMLNTLIDQTTRNLTKRERTNFETLITIHVHQRDIFDILCRMNIKSANDFEWLKQCRFYFKEDLDKTWISVTDVTFTYQNEYLGCTDRLVITPLTDRCYITLAQALTLSMGGAPCGPAGTGKTETVKDMGKTLAKYVVVFNCSDQMDYRGLGRIYKGLAQSGSWGCFDEFNRIELPVLSVAAQQVAVVLTAKKEKRKTFLFTDGDTIEMNPEFGIFITMNPGYAGRKELPENLKIQFRTVAMMVPDRQIIIRVKLASCGFLENITLARKFYTLYKLCEEQLTKQVHYDFGLRNILSVLRTLGAAKRRNSKDTESTIVMRVLRDMNLSKLIDDDEPLFMSLVSDLFPNQTLEKTNYPELEAAILQQTDEASLVYHPPWVLKLIQLYETQHVRHGIMTLGPSGAGKTTCIHTLMKAMTQMGDNHREMRMNPKAITAAQMFGRLDVATNDWTDGIFSALWRKTLKLKAGEHVWLVLDGPVDSIWIENLNSVLDDNKTLTLANGDRLTMAPTVKIIFEPHNIDNASPATVSRNGMVYMSSSGLDSRPIVQAWLKNRAPGEKSTFSDLFDQTFVEVYNWGVQMVKLQMPVLQCNIVQQMLFILEGLIPVKKEDEQAVSMSSKESHDANKRLEHQKHVEEARRQSIGSQIVEDLPPETSIEEKEDTCTPEHLHRLYIFALAWGLGGYLSTSDRQRMNLFVK-ESFPQLDYP-KGSAHENTIFDFFVSPAGVWQSWKTLVTPYMYPELSTPDYLSILVPIVDNVRIDYLIGTIANQERAVMVIGEQGTGKTVIMKNFMKKMNVESYMGRSFNFSSATSPYQFQRTIESYVEKRVGVTFGPPGGRKLIVFIDDINLPEINEWGDQITNEIVRQSMDMKGFYSLEKPGDFTTIVDVQYVAAMGLPGGGRNDIPSRLKRQFCVFNCNIPDNDSIDKIFRVIGEGHYNAKRGFVPEIRSLVKKLIVVTRHLWQRTREKLLPTPAKFHYVFSLRDLSRIWQGMVGTLSTVITSESVLMALWKHECTRVFADRFTTFQDKEWFGSELACLVREELGDSHSQMILP--NPVFVDFMRDAPEPTGEEGEDTDMELPKVYEPVHSHEVLRERLVMFLAQFNEMVRGSGMDLVFFPDAMLHLVKISRIIRHPRGSVMLVGVGGSGKQSLTKLASFIAGYKTFQIALTRSYNVANFLEDLKLLYRTCGVQGKGTTFLFTDMDIKEEGFLEYLNNILSSGVISNLFSRDEQAEIVQELTPVMKRENQRKTATPESVMDFFLARTCTNLHVAFCFSPVGETFRSRVQRFPALVSGCTIDWLHPWPKDALVSVARHFLSHFEIECTPAVKEELVNALGSIQDIVAETSQEYFQRFRRATHVTPKSYLNFIAGYKNIYQMKQQELRDGVEKMDTGLEKLKEASASVEILKKDLVVMEEELVEASKNAESVLVEVTERAMQAEIVKNQVLIVKDKAEALVACIAHEKALAEEKLEAAKPALEEAENALNTIKPAHIATVRKLGRPPHLIMRIMDCVLILFKRKLHPCIPDAGTPCPKPSWQESLKMMASATFLLQLQNYPKDTINDEMIDLLQPYFRMEDYNMDMARRVCGDVAGLLSWTKAMSFFHSVNKEVLPLKANLTMQEARLKLAMDDLAGAEEQLREREEALQAVKDQYDKAVGEKQRLTDAANVCLRKMTAATALINGLSDEKHRWTNQSKEFKIQLGKLVGDVLLATGFLSYCGPYNQEFRANLIKT-WMGILKQKNIPFTTGLNIINMLVDSSTVSEWTLQGLPNDELSVQNALIATKSSSYPLLVDPQTQGKIWIKCKEDRNELQITSLNHKYFRTHLEDSLSLGRPLLIEDVGIDLDPVIDNVLEKNFIKSGSIEKVLVGDKECDVMPGFMLYITTKLPNPAFSPEVSAKTSIIDFTVTMRGLEDQLLGRVILMEKSDLEAERVALFETVMQNQRNMKELEANLLLRLSSSQGSLVDDEALIEVLRVTKTTAEEVNQKLKISEVTERKIMKAREEFRAVAKRGSILYFLIVEMSNVNAMYQNSLKQFLVIFNHSITKSTKSSVTEERINIILRYLTYEVYKFTNRSLYERHKQLFTLMLAIKIDYHNGNISHEEFLTFIKGGASLDLNAVTPKPFRWILDITWLNLVEISKLETFSTVLQVIELNEKDWRCWYECEKPENEEIPCGYNAILDGFRKLLLIRSWCPDRTISQAKKYIEESLGPEYSEMQILDLEEMWLESEPRTPFVCLLSIGSDPTTQIGALAKQKSIVLKSVSMGQGQEYHARKMIIESMAIGGWVLLQNVHLSLPFCSEIIDMLVESEHIDDSFRMWVTTEPHNEFPIGLLQMALKFTNEPPQGIRASLKRSYQSFTQDFLDYTSATQWPPLLYTVAFLHTIVQERRKFGPLGWNIPYEFNQADFAASVQFIQNHLDEMDPKKGVSWQTLVYMIGEVQYGGRVTDDFDKRLLTTFTSVWFCEPLLSNSFEFYKGYKVPGTKSLQGFIDYINSLPAYDTPEVFGLHSNADITYQINSAKGILDTILSVQPKEGGGGGGETRESIVYQLADDMLRKLPAQYNAYEVRENLTRMGILLPMNIFLRQEIDRMQRVIKRVHTCLCDLKLAIDGTIVMSPALKESLDAMYDARIPETWMKISWESTTLGFWYTELLERNGQFRTWISTDRPKVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDSVVLQNQITRYNKEDITEYPTEGVYVHGLFLEGASLDRRSGKLIESKMKVLYEQMPVIYIYAINTTAGKDPKLYECPIYRKPQRTDLKYVGSIDFETEFNPKHWTLRGVALLCDIK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : ::.:* :* .: : :: . * .: : ::: :: :..:* . * **: : . : ::: :. : *::: * . : . : .:: :*: *:..:..::. :*: :: . . : : : : * . .: : :..:. : :.. : ::* : * * ::* *..*: ** *. ** **::**: ::*. :: :::. . : .: * * *:::* *:: * ::* **::** ::: ::*. *..** : ::* ..* *::::::::*:*::*****: ::*::*:***:: :**::** . :*.* : *: * * : *: : .::: .. * .** ::****::* .** ** .::. . *. * : :**: ::: :...:*. ** *. :*: *:. * : . *. : ::: * .: .: :.: * :*:::. :. . ::. ::: : : .*: ***:* : ** **:* * * * :: : :: . : : .* : *:.: :* *:* *: : : . :: :*:**:.* * .**:. : : : :. * * . .. :: :: : . *: *:: :: : ** :.*:. : .. :. :: *: :::*: . :* :* : * *. :. :::: .: . * *: ** *.**.:*:: :. :: . . . * . . : *: .:.:: * * : * :*:::::*: . . .: . * **:: : * *:::*. : . :.:** :*. . : .. : . . : . . :.:: : ::*:: * * *:: .. : :. :. *: :* : : :: . * *:.: : :: :: .* .: ::. :* .*: * *: : : :.:*: :*. : .::* :**.* *:****:*: * :* **:.::. :: :.****:: :* :: : : :*: : **.*: ::::* : : ..* :* :** *: .* :: * :* : * *** .: *::**.** :** .*:.::*: *: .**:***** * : * : :::*.****:* **: *: :..* : * ::.*:.** **::** ******:.**:* *: :** **:*.: ****: *:.:** ***.** :* ::. .: * *:**:*.**** *::********:**:*** *: ** :* : : * *: :*****:* :.* * :*****:****:***** **: **:** **.:.:*:* *: ***:*:****************:*****.:***** *** **** *.*: .****: : ****** :***:*****:****:**: **********.*************** ** : ** : * ** *::: :: * *** * ** .: *:* ** ** ** *** :** * *.:..* * **. ***:*******:**:*:* ** .: ::*:* **: **::** **. **::* :*.::*************** * ::::** *******.****:** *: : :*** * ****:************************ :.*****.**********.****: *.*************:******:******************:**********: ::**.:**::* *:*:*** : :*****:*:*********:********:**:***********:*********::*: **:**:.**:******:********************: ** *:* : *** *********:*:*****:**:.****. *:. *.:*::*: .*. .*: **** **::**:**. ****:*:*****:***: * **:::*: * *************.*******.***********:******: * **:::::******:*************:*********:.***. *::** ***:********* ***::*** *. **::.:**.*: * : .*: . * : * : : :* :*:. : * :*:*** * *: . *: :*::*.: *. *. *. ..* ::: ::: . *. * .* ::::*: * * *. *.** : *:* ***** ***:* ::** ***:* :**:: *****.***::* ::.* : * :.:****** * ***::****:**:* *:** .*:*: :****:*:* *******:******* *: .*::.*:***:**.***:* :*** *******:*.****** :***.:*.: *:**** :** *:: . * * *: . : .*: : * *** *: *:****::***:*.******:****: : . *: *:****.**:**** .* **.. : *.*::. . : :. ****:** **.:*: *:: : **:** : * . * *:* .: :** :**:.:*:*** *** **:****:** . *..:************::******** ***:******.:*:::*** **:..* :*** :*:*** :**:*.****:**:**** :****:*** ** . * .:**:* : .* :.: ::*::* ***:.:******* ** * :**.*:****:**: ***:**::*: :**: : * *: :* .:*:.:* ::* *:*.. :****:** :********.** .** ** * :. .::*: **:** *** ** *.::* *:** *. :*: ** *** * : ** :* ***:*: :* * :*. **.*****:******* **:**:* .*****.*.:*************:**:::: . * . * *** ****:*:: ** .**::******:* :::*.*** * **. : *::***:**** *** **: *..:*:********* ** * :* :* *: * :: *: *: ::: *: ** ", "identical_positions": 1362, "similar_positions": 985, "identity": "27.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-178", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZNB6-1", "uniprot_id": "NFXL1_HUMAN", "id": "Q6ZNB6-1", "name": "NF-X1-type zinc finger protein NFXL1", "aln": "MEASWRQVAGGRGRSRGRATAAP-SGNGVHLRGAGGGREKGSVGAVPSGTSPGGVATTAAAGSRHSPAGSQALQTTAA-----SELMSQKKFEEIKKANQAAARKLVEEQFSSSSEE-GDEDFE--GKQGKILANTFITYTTQT-DGDTRELERTKQYVNEAFQAGAMTCLICIASVKRNQAVWSCSGCFCIFHMPCIQKWAKDSQFLVSSVTDDDFGKKDCPWPCPKCRFEYKRSETPSRYYCYCGKVEDPPLDPWLVPHSCGQVCEREFKPPCGHKCLLLCHPGPCPPCPKMVTTTCYCKKAKPIPRRCSAKEWSCQLPCGQKLLCGQHKCENPCHAGSCQPCPRVSRQKCVCGKKVAERSCASPLWHCDQVCGKTLPCGNHTCEQVCHVGACGECPRSGKRFCPCQKSKFSLPCTEDVPTCGDSCDKVLECGIHRCSQRCHRGPCETCRQEVEKHCRCGKHTKRMPCHKPYLCETKCVKMRDCQKHQCRRKCCPGNCPPCDQNCGRTLGCRNHKCPSVCHRGSCYPCPETVDVKCNCGNTKVTVPCGRERTTRPPKCKEQCSRPPTCHHTSQEKHRCHFGSCPPCHQPCQKVLEKCGHLCPAPCHDQALIKQTGRHQPTGPWEQPSEPAFIQTALPCPPCQVPIPMECLGKHEVSPLPCHAVGPYSCKRVCGRILDCQNHTCMKECHKVTKTDGCTGKNKAGPECLHCEEGCSKSRPLGCLHPCILRCHPGECPPCVQMLRIKCHCKITSLYVECRKITTADVNEKNLLSCCKNQCPKELPCGHRCKEMCHPGECPFNCNQKVKLRCPCKRIKKELQCNKVRENQVSIECDTTCKEMKRKASEIKEAEAKAALEEEKRRQQAELEAFENRLKGRRKKNRKRDEVAVELSLWQKHKY-YLISVCGVVVVVFAWYITHDVN----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9Q8I7-1", "uniprot_id": "E9Q8I7_MOUSE", "id": "E9Q8I7-1", "name": "", "aln": "MDAPWRQVAAGRGRARGRATAVPLSGNGVPFGGAGGGRAKGSGGAVSSGPGPGGAAALAPAGRGQRSAGGEAPQPPGARGEDGSELMSQKKFEEIKKSNQAAARKLLEEHCSSSSEEEGDEDLE--GKQGKIVANTFTTYTTHT-DGDIHELERTKQYLNEAFQAGAMTCLICIASVKRNQAVWSCSGCFCIFHMPCIQKWAKDSQFLVSSVTDDDFGKKDYPWPCPKCRFEYKRSETPSRYYCYCGKVEDPPLDPWLVPHSCGQVCEREFKPSCGHKCLLLCHPGPCPPCPKMVTTTCYCKKAKPIPRRCSAKQWSCQLPCGRKLLCGHHKCENPCHAGNCQPCPRVSRQKCVCGKKVAERSCASPVWHCDQVCGKTLPCGNHTCEQVCHVGACGECPRSGKRSCPCQKSKFSLPCTEDVPTCGDSCDKILECGIHRCSQRCHRGPCETCRQEVEKQCRCGKHTKRMPCHKPYLCETKCVKMRDCQKHQCRRKCCPGNCPPCDQNCGRTLGCRNHKCPSVCHRGSCYPCPETVDVKCNCGNAKVTVPCGRERTTRPPKCKELCSRPPTCHHASQEKHRCHFGPCPPCHQPCQKVLEKCGHLCPESCHDQALVKQTGRHQPSGPWEQPAEPAFIQTALPCPPCQVPIPVECLGKHEVSPLPCHAVGPYSCKRLCGRMLRCQNHTCMKECHKVTEVDSSTGKNKAGPECFHCEEGCSKSRPAGCPHPCVLPCHPGKCPPCVQMLRIKCHCKITSLYVECRKITTADVSEKNLLSCCKNQCPKELPCGHRCKEMCHPGECPFNCNQKVKLRCPCKRIKRELPCNKVRENQVSVECDATCKEMKRKASEVKEAEANAALEEEKRRQQAELEAFENRLKGRRKKSRKRDEVAVELSPWQKYKS-YLLPVCAVVVAVLMWYIFHGVD----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32THU4-1", "uniprot_id": "A0AB32THU4_DANRE", "id": "A0AB32THU4-1", "name": "", "aln": "MDPVWRQQGRGRGQGQGRGQVTG---------NPSSGRARGAVGSQVKAS-------------------------------------SQSRFDEIQKSDRAAAQRLTTDTYSSSSEEEDDDDSEDGGKRGKILQSALSPYASHTGDTDGRLLEQTRHYLHEVCQSGGVTCLICIASVRRTQPVWSCVGCYCIFHITCIQKWAKDSIFLVSSVTDEDFGKKDHPWPCPKCRHEYSPHQTPTRYYCYCGKEAEPAPDPWLLPHSCGQVCGREFKPSCGHRCLLLCHPGPCPPCPQMVSVSCLCGKSSRVPRRCSAKAWSCTKICGRKLPCRTHTCANTCHAGECAACPRVSLQACACGRQRAERPCASPEWHCDQVCGRSLSCGNHTCERVCHAGVCGECPRAGNRSCSCGKTKSVLPCTVDVPTCGDTCGKNLDCGLHTCSMRCHRGACETCRQEVEKTCRCGRYSKLLPCHKEYLCESKCNKTRACSRHQCKRKCCPGNCPPCDMNCGRMLGCRNHKCPSVCHQGSCYPCPEMVKVGCECGSTVISVPCGRERSTKPPRCKELCKKPPSCHHASQEKHRCHFGPCPPCKQPCQLTLAGCVHLCPAPCHDQVLVKATDRANLAGPWEQPSTPAFVRTALPCPPCLVPIPTACLGEHEVSPVPCHARGPFSCGRLCGRTLSCGNHKCSLECHHVTPTPNSD-KTMAGQECVRCEEGCVKPRPAGCAHPCVLPCHRSACPPCRLMLRQRCHCKISSLYIECLKFTSADEQDKQLLMSCQNQCPKQLLCGHRCKLLCHAGDCDQNCGQKVKIRCPCKRIKKDFPCSRVQSQDGLLECDETCQTLQKKHAEACAAEERALLEGEMRKQQAELEAFEKRQKGRRKKNRKVTEVEMEEGVWHRYKLRLLLPFCVVLLAVAAFYLLKLTNEVTDSESAGH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:. *** . ***:.:**. .. ....** :*: *: ... **.:*:**:*:::***::* : ****** .*:* * **:***: .:: .*:::* * * : **:*::*::*. *:*.:*********:*.*.**** **:****:.********* ********:****** ********.**. :**:******** :*. ****:******** *****.***:**************:**:.:* * *:. :******* *** **:** * *.* *.****.* .***** * *.**:: ***.**** ********::*.*******:***.*.******:*:* *.* *:* **** *******:*.* *:**:* ** *****.********** ****:::* :**** ****:** * * *.:***:************ **** *************:******** *.* *:**.: ::*******:*:**:*** *.:**:***:**********.****:**** .* * **** .****.*:* *.* : :******: ***::******** **** ***:*****:**** **:** *:*** * * **.* ***:** . .. *. ** **.:***** *.** ** ***:* ** . **** *** :*****:***:** *:*:** .:*:** .*:*****:* ****** :**.*:* **.****:********::: *.:*:.:: :*** **: :::* :* ** .* ** * *:*********:* ******.** ** :* . *:::* *:..* *::.* :*: : .: ", "identical_positions": 542, "similar_positions": 197, "identity": "58.15%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-183", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EQQ3-1", "uniprot_id": "GPR63_MOUSE", "id": "Q9EQQ3-1", "name": "Probable G protein-coupled receptor 63", "aln": "MVVSGVLTAPAVLTAPHSGTSNTTFVVFENSHVNITAPLPFQHPSAGPLLRYSLETMTSPGFSSLAVNSTAVTPAPAVFKSLNLAVQIILSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRLSAMFFWLFVIEGVAILLIISIDRFLIIVQRQDKLNPYRAKVLIAVSWATAFSVAFPLAVGNPDLQIPSRAPQCVFGYTTNSGYQAYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPRLPGHTRRRIRPSAVYVCGEHRTVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZJ6-1", "uniprot_id": "GPR63_HUMAN", "id": "Q9BZJ6-1", "name": "Probable G protein-coupled receptor 63", "aln": "MVFS------AVLTAFHTGTSNTTFVVYENTYMNITLPPPFQHPDLSPLLRYSFETMAPTGLSSLTVNSTAVPTTPAAFKSLNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNMPFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQRQDKLNPYRAKVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFFIPFLVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTTILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALNPLIYYWRIKKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FF58-1", "uniprot_id": "E7FF58_DANRE", "id": "E7FF58-1", "name": "", "aln": "MLYS------STSPPVDSGQPNP------------SARPASQPVGARAMENSSTKLNSSPDFRTLSEYITPSSVWQEPVEGLNLPLQVFLGLVIICVLLLAFLGNMVVCVMVYQRAAMRSAINILLASLAFADMMLAVLNMPFALVTMVTTHWIFGDVFCRVSAMFFWMFVMEGVAILMIISVDRFLIIVQKQDKLSPRSAKLLIAVSWSLSFCFSFPLSFGYPALYIPPRAPQCVFGYTAERGDHAYVMLIMLLFFFVPFLVMLYTFMGILSTLRHNALRIHSHPDSVCLSQASKLGLMSLQRPFQMNIDMSFKTRAFTTILILFSVFTACWAPFATYSLLSTFSRTFYYRQNFFQISTWLLWICYLKSALNPLIYYWRIKKFRDACLDLMPKYFKFLPQLPGHTKRRIRPSAVYVCGEHRSVV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * :. .. .:* .*. : . * . .: . * : :...: :*: *. . .:.***.:*: *. ::* :*:::****:***:****:*******************:************::**:****..***:******:**:******:***:********:****.* **:******: :*..:***:.* * * **.**********:: * :***:** *: **:****:**:*****.***********:*:.:*******************.***.*************:** .*****:****::***: ***::***:*******:*******************:*****:*** *****:*****:***************:*:", "identical_positions": 270, "similar_positions": 94, "identity": "63.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-185", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10415-1", "uniprot_id": "BCL2_HUMAN", "id": "P10415-1", "name": "Apoptosis regulator Bcl-2", "aln": "MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGAC-ITLGAYLGHK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P10417-1", "uniprot_id": "BCL2_MOUSE", "id": "P10417-1", "name": "Apoptosis regulator Bcl-2", "aln": "MAQAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDADAAPLGAAPTPGIFSFQPESNPMPAVHRDMAARTSPLRPLVAT---AGPALSPVPPVVHLTLRRAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGAC-ITLGAYLGHK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F8W266-1", "uniprot_id": "F8W266_DANRE", "id": "F8W266-1", "name": "Apoptosis regulator Bcl-2", "aln": "MAQEN--VYNNRSIVENYIHHKLWKKGYVWEVNGHDSVSNGLS-----MGRQENSVVSPSSRHDPYS------------------------ALHNVLREAGDELESLYQSDFAEMSKQLHVTSITAHQRFNAVIDELFRDGVNWGRIIAFFEFGGTVCAECVNKEMTGQVDNIAVWMADYLNGPLHGWIRENGGWEAFVELYSSQRDSVFHSSWSSIVTVFGLAALGAVGLTIGAYLAQQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: . *:**.** :***:** ::** *:... .:.. * : :. * *: :* : .:* .**.***::. *: ******.***:*.:**: ** :*::************:*******.:*.*.**:**: *****:**::*** ** **::****:******... .:*. ** *: *::.** :** :*:****.::", "identical_positions": 104, "similar_positions": 67, "identity": "43.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-188", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q70J99-1", "uniprot_id": "UN13D_HUMAN", "id": "Q70J99-1", "name": "Protein unc-13 homolog D", "aln": "-----------MATLLSHPQQRPPFLRQAIKIRRRR---VRDLQDPPPQMAPEIQPPSHHFSPEQRA------LLYEDALYTVLHRLGHPEPNHVTEASELLRYLQEAFHVEPEEHQQTLQRVRELEKPIFCLKATVKQAKGILGKDVSGFSDPYCLLGIEQGVGVPGGSPGSRHRQKAVVRHTIPEEETHRTQVITQTLNPVWDETFILEFEDITNASFHLDMWDLDTVESVRQKLGEL-TDLHGLRRIFKEARKDKGQDDFLGNVVLRLQDLRCREDQWYPLEPRTETYPDRGQCHLQFQLIHKRRATSASRSQPSYTVHLHLLQQLVSHEVTQHEAGSTSWDGSLSPQAATVLFLHATQKDLSDFHQSMAQWLAYSRLYQSLEFPSSCLLHPITSIEYQWIQGRLKAEQQEELAASFSSLLTYGLSLIRRFRSVFPLSVSDSPARLQSLLRVLVQMCKMKAFGELCPNTAPLPQLVTEALQTGTTEWFHLKQQHHQPMVQGIPEAGKALLGLVQDVIGDLHQCQRTWDKIFHNTLKIHLFSMAFRELQWLVAKRVQDHTTVVGDVVSPEMGESLFQLYISLKELCQLRMSSSERDGVLALDNFHRWFQPAIPSWLQKTYNEALARVQRAVQMDELVPLG---ELTKHSTSAVDLSTCFAQISHTARQLDWPDPEEAFMITVKFVEDTCRLALVYCSLIKARARELSSGQKDQGQAANMLCVVVNDMEQLRLVIGKLPAQLAWEALEQRVGAVLEQGQLQNTLHAQLQSALAGLGHEIRTGVRTLAEQLEVGIAKHIQKLVGVR--ESVLPEDAILPLMKFLEVELCYMNTNLVQENFSSLLTLLWTHTLTVLVEAAASQRSSSLASNRLKIALQNLEICFHAEGCGLPPKALHTATFQALQRDLELQAASSRELIRKYFCSRIQQQAETTSEELGAVTVKASYRASEQKLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPELAARETQKHKKDLHPLFDETFEFLVPAEPCRKAGACLLLTVLDYDTLGADDLEGEAFLPLREVPGLSGSEEPGEVPQTRLPLTYPAPNGDPILQLLEGRKGDREAQVFVRLRRHRAKQASQHALRPAP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B2RUP2-1", "uniprot_id": "UN13D_MOUSE", "id": "B2RUP2-1", "name": "Protein unc-13 homolog D", "aln": "-----------MATHLSHPQRRP-LLRQAIKIRRRR---VRDLQDPPPQATQEVQVQSHHFSPEERD------LLYEEALYTVLHRLGQPEPNHVKEASELLSYLQEAFQVQPEEHQQMLRRVRELEKPVFCLKATVKQAKGILGKDVSGFSDPYCLLGIEQKVGVAEGSPVSRRRQKAVVKHTIPEEETHRTQVKSQTLNPVWDETFILEFEDIANASFHLDMWDLDTVESVRQKLGEL-TDLHGLRRIFKEARKDKGQDDFLGNVVLRLQDLRCREDQWFPLEPCTETYPDRGQCHLQFQFIHKRRATAASRSQPSYTVHFHLLQQLVSHEVTQHQAGSTSWDASLSPQAVTILFLHATQKDLSDFHQSMAQWLAYSRLYQSLEFPSSCLLHPITSIEYQWIQGRLKAEQREELATSFTSLLAYGLSLIRKFRSVFPLSVSDSPSRLQSLLRVLVQMCKMKAFGELCPDSAPLSQLVSEALRMGTVEWFHLMQQHHQPMVQGILEAGKALLNLVQDVMGDLYQCRRTWNKIFHNVLKIDLFSMAFLELQWLVAKRVQDHTVAAGNLVSPDIGESLFQLYVSLKELCQLGPVPSDSREVLALDGFHRWFQPAIPSWLQKTYSVALERVQRAVQMDTLVPLG---ELTKHSTSAVDLSTCFAQISHTARQLDWPDPEEAFMITVKFVEDTCRLALVYCSLIKARARELSAVQKDQSQAADMLCVVVNNMEQLRLIIDKLPTQLAWEALEQRVGAVLEEGQLQNTLHAQLQGALAGLGHEIRTGVRTLAEQLEVGIATHIQKLIGVK--ESVLPEDAILPLMKFLEVKLCYMNTNLVQENFSSLLTLLWTHTLTVLVEVASSQRSSSLASGRLKVALQNLEVCFHAEGCGLPPEALHTDTFQALQNDLELQAASSRELIQKYFCSRIQQQAETTSERLGAVTVKVSYRASEQRLRVELLSASSLLPLDSNGSSDPFVQLTLEPRHEFPEVAPRETQKHKKELHPLFDETFEFLVPAEPCQKAWACLLLTVLDHDRLGADDLEGEAFLPLCRVPGLTDCAEPGEAPQMRLPLTYPAPNGDPILRLLESRKGDREAQAFVKLRRQRAKQASQHAP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F6NFN1-1", "uniprot_id": "F6NFN1_DANRE", "id": "F6NFN1-1", "name": "", "aln": "MVPVQDGASSQGENLLLPPKETHSDTSGSGKIRPRQSSPARRLGMTRRQNRKDFKDSENPEESEKRHKEKELKPLYKELLYTITHRLGKPHIKQQYSQKQFQDYIREAFTMTEDEHKTLSEKVQSSLAPTYCLVVTVKQAKGILGKDISGFSDPYCLLTILSEDKESPGGGASNKPQKAVVRESAKG-QVLQTSIKKQTLNPIWDETFKLEFENIN-GNFHMEMWDKDEEVSLVQKFDEFCTNIHGIKRMIKDAKKEKGQDDFLGNVVLKLKDLHCTEDTWYNLEPRTETYPDRGRCHLQLKFIHKERDETLSAGRSPYVNYCGILQQFVQAHISKQQD-SNPWKGELCGEGTALLEYYANQNDISPFLQDLAKWVAYSKLYQSLEVDSTVLFQQLTSIEYHWDQQELPHQQKQELGDSLHGFLQYGLCLVSKYRDIYPPTTKTTP-RLHTLLRVLVQICKTRAFQKLNPAQFDLHVEVTDAVVNGTEEWFNIKKGLHQPMTKDLLETVSALSRLIGEVQEDVRLSKDVWNKVFVSAVQLDVFTVVYQKLDTLLAEELRATLSQLENQMDQPLANSLFPVYLSLQTIHKDKAFLQKRAKLLQLTSFHEDFRDALPYWLNKAFSTTMERVKKAVHVDQLQPLQSGTVPIKHSSSAVDIAACLHPIAQLWDQLSWPDPEEAFMLMVKLTEDVCKIASTYCQMLKARVKELSE-DSDQESAIKMLCVVVNDLEHLHTVLTRLPKQLNWAGLRERTRLVIGETQFQNTLPSQLQHTQSLLNREIRSAVDRLGKKLKTDIESHVRSMASRQRFPSRDTEEAVVPLMKYLEKELQYMNENLVQENFNSLLTPLWMNSVKILHQISQQEDSNLVYFQRLLYTLQCLEQCFYAEGNGLPLETLHTEEYKVLRANLTQNSLTSNQLIEKFFERKVWEQKVFNGEKYGAVTLITSYKRSENKLHVEVLNAVNLIPLDSNGSSDPFVQLSLEPRHLFPEVEQRSTKIKSCDLNPLFEESFEFLISLQQCQSPGACLLVTVLDHDTLRSDDFEGEAFLSLKAVPGVGGGLQNPEPAQIRLPLMHPKPNSENTLRLLEARKGEKEAQAFIKLRRQREKKSQEA------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * *:. : *** *: .* * . * :.: .: ..*:* **:: ***: ****:*. :: . .:: *::*** : :**: .:*:. * :** .************:********** * . . *. *.: *****:.: :. :*.: .*****:***** ****:* ..**::*** * *: **:.*: *::**::*::*:*:*:************:*:**:* ** *: *** ********:****:::***.* : * .:..*. : :***:*. .::::: *..*...*. :..::* :*.*:*:* * *.:*:*:***:******. *: *:: :*****:* * .* :*::**. *: .:* ***.*: ::*.::* :.. :* **::*******:** :** :* * * *::*: ** ***:: : ****.:.: *: .** *: :* *: .: .*:*:* ..:::.:*::.: :*: *:*:.:: : :. :.:*** :*:**: : : .. :* * .**. *: *:* **:*::. :: **::**::* * ** ***:****:::*: *:: **.*********: **:.**.*::* .**.::***.:*** :.** .* .*******::*:*: :: :** ** * .*.:*. *: : *:**** :*** : : *.:***:.* *.::*:..* .*::.: . : * .*:*::****:** :* *** *******.**** ** :::.:* : : .: *. : ** :** ** **:*** *** ::*** ::.*: :* :: :*.:**.*:* :: :* ..*. ****: .**: **::*:**:*.* .*:**************:***** ***: *.*: :. :*:***:*:****:. : *:.. ****:****:* * :**:******.* ***: . : * .* **** :* **.: *:***.***::***.*::***:* *::.: ", "identical_positions": 465, "similar_positions": 360, "identity": "41.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-190", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51816-1", "uniprot_id": "AFF2_HUMAN", "id": "P51816-1", "name": "AF4/FMR2 family member 2", "aln": "MDL--FDFFRDWDLEQQCHYEQDRSALKKREWERRNQEVQQEDDLFSSGFDLFGEPYKVAEYTNKGDALANRVQNTLGNYDEMKNLLTNHSNQNHLVGIPKNSVPQNPNNK-NEPSFFPEQKNRIIPPHQDNTHPSAPMPPPSVVILNSTLIHSNRKSKP---EWSRDSHNPSTVLASQASGQPNKMQTLTQDQSQAKLEDFFVYPAEQPQIGEVEESNPSAKEDSNPNSSGEDAFKEIFQSNSPEESEFAVQAPGSPLVASSLLAPSSGLSVQNFPPGLYCK-TSMGQQKPTAYVRPMDGQDQAPDISPTLKPSIEFENSFGNLSFGTLLDGKPSAASSKTKLPKFTILQTSEVSLPSDPSCVEEILREMTHSWPTPLTSMHTAGHSEQSTFSIPGQESQHLTPGFTLQKWNDPTTRASTKSVSFKSMLEDDLKLSSDEDDLEPVKTLTTQCTATELYQAVEKAKPRNNPVNPPLATPQ--PPPAVQASGGSGSSSESESSSESDSDTESSTTDSESNEAPRVATPEPEPPSTNKWQLDKWLNKVTSQNKSFICGQNETPMETISLP-PPIIQPMEVQMKVKTNASQVPAEPKERPLLSLIREKARPRPTQKIPETKALKHKLSTTSETVS-QRTIGKKQPKKVEKNTSTDEFTWPKPNITSSTPKEKESVELHDPPRGRNKATAHKPAPRKEPRP--------NIPLAPEKKKYRGPGKIVPKSREFIETDSSTSDSNTDQEETLQIKVLPPCIISGGNTAKSKEICGASLTLSTLMSSSGSNNN---LSISNEEPTFSPIPVMQTEILSPLRDHENLKNLWVKIDLDLLSRVPGHSSLHAAPAKPDHKETATKPKRQ--TAVTAVEKPAPKGKRKHKPIEVAEKIPEKKQRLEEATTICLLPPCISPAPPHKPPNTRENNSSRRANRRKEEKLFPPPLSPLPEDPPRRRNVSGNNGPFGQDKNIAMTGQITSTKPKRTEGKFCATFKGISVNEGDTPKKASSATITVTNTAIATATVTAT--AIVTTTVTATAT--ATATTTTTTTTISTITSTITTGLMDSSHLEMTSWAALPLLSSSSTNVRRPKLTFDDSVHNADYYMQEAKKLKHKADALFEKFGKAVNYADAALSFTECGNAMERDPLEAKSPYTMYSETVELLRYAMRLKNFASPLASDGDKKLAVLCYRCLSLLYLRMFKLKKDHAMKYSRSLMEYFKQNASKVAQIPSPWVSNGKNT--PSPVSLNN--VSPINAMG-----NCNNGPVTIPQRIHHMAASHVNITSNVLRGYEHWDMADKLTRENKEFFGDLDTLMGPLTQHSSMTNLVRYVRQGLCWLRIDAHLL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O55112-1", "uniprot_id": "AFF2_MOUSE", "id": "O55112-1", "name": "AF4/FMR2 family member 2", "aln": "MDL--FDFFRDWDLEQQCHYEQDRSALKKREWERRNQEVQQEEDLFSSGFDLFGEPYKVAEYTNKGDALANRVQNTLGSYDEMKDLLSNHSSQNHLVGIPKNSAPQTPISK-SEASFYPEQKNRMIPSHQETTHSSTPMPPPSVVILNSTLIHSNRKSKS---EWPRDSHNTSPAQASQTSSQPNKMQTSTQDPPQTRLEDFFVYPAEQPQIGTVEKSNPSSKEENNPNSGGEDTFKEIFQSNSPEESEFTVQAPGSPLVASSLLAPSSGLSVPTFPPGLYCK-TSMGQQKPTAYVRPMDGQDQATDISPTLKPSIEFENSFGNLSFGSLLDGKPSAVSSKTKLPKFTILQTSEVSLTSDPSCVEEILRE-----------------------------SQHLTPGFTLQKWSDPSSRASTK------MLEDDLKLSSDEDDLEPVKTLTTQCTANELYQAVEKAKPKNNPVNPLLATPQ--STPATQTNVGSGSSSESESSSESDSDTESSTTDSESNEAPRVATPEPEPPSTNKWQLDKWLNKVTSQNKSFICGQNETPTETISLP-PPIIQPVEVQVKVKPNPSQAVAVPKERPLLSLIREKARPRPTQKTPETKALKHKLSTSVDTVS-QRTIGKKQPKKVEKNTSFEEFTWPKPNITNSTPKEKGSVELPDPPRSRNKATAHKPVPRKEPRP--------HVPLATEKKKYRGPGKIVPKSREFIETDSSTSDSNTDQEETLQIKVLPPCITS-----KSKETSNASLTLSTLTN--GNSNN---LSTSNEETAFSPPPAMQTELLSPLRDHENPKNLWVKIDLDLLSRVPGQNSVPVTPAKTDYKETASKPKRQ--TAATAVEKPAPKGKRKHKPAETAEKIPEKKQRLEDNTTICLLPPCISPAPPHKPPSTREN-SSRRANRKKEEKLFPPALSPLAEDPPRRRNVSGNNGHFGQDKNISMAGQITSSKPKRSEGKFCATFKGISINEGDAPKKAASATVTVANMALATATATATVPAIVTATVTATATTTATATTTTTTTTISSITPTITSGLMDSSHLEMTSWAALPLLSSSSANVRRPKLTFDDSVHNADFYMQEAKKLKHKADALFEKFGKAVNYADAALSFTECGNAMERDPLEAKSPYTMYSETVELLRYAMRLKNFASPLASDGDKKLAVLCYRCLSLLYLRMFKLKKDHAMKYSRSLMEYFKQNASKVTQIPSPWVGNGKNT--PSPVSLNN--VSPINSVG-----NCNNGPVTIPQRIHHMAASHVNITSNVLRGYEHWDMADKLTRDNKEFFGDLDTLMGPLTQHSSMTNLVRYVRQGLCWLRIDAHLL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B5H1-1", "uniprot_id": "A0ACD6B5H1_DANRE", "id": "A0ACD6B5H1-1", "name": "", "aln": "MDLFEFDFFRDWELEQQCHYEQDRSALKKKEWERRTQEVQQDEDLFSTGFNLFGEPYK----TNKGDALANRVQNTLGNYDEMKELLTSHSNQSHLVGIPKNSVPQTPVEKPDQPGFFPEAQRSRPALSQPGSHSTSMPPPPANTIPGSSVMHGHQSKKSRSSDWSQGGHRSSGVQTTQAASRG---KHSSHEQTSNRHDQDQEDSSPNP-NGPTTSSHSSRKQ---AQAGKGPATAELGLGKSPAEQDSCSHGSSSPLASTSLLP--SGLSTPTFPQGLHCKPSSAVQQKPTAYVRPMDGQDQVPNDSPELKPPVELVEGYNTVPFGGLLDTKSSTTGTKGKIPKLTLPQSGEVSLPNDSNCVEEILREMTHSWPPPLTAIHTPGKAEQTKFPIPSKDSQHVTSGYNAKRCSVPSNKPATKSVPQKSMLEDDLKISSDEEDND---------------QAAEKPKPRSTALNLPGSTAVRSSEAAGHSSGASGSSSESESSSESDSDSESSSSDSECNRASRAATPEPEP---SKWQLDKWIKKVNPHNKALINTQADSHGLNSSQPDESQTSENQSYSKSKPSTALAPADPKERTLLSPIREKAKPKAGQKAPDSKSTKVKSPASVELAPPRRSTGKKQPKKVERSSSSEEHNWPRPGNSSSTPKEKEPPPLE-PPKPRGKGPVVKTAPRKEPRTTTTSTAPTNIAPVPDKKKHRGPNKIIPKSKEFIETESSSSECHSDPEE--LTKVQLPCPGPNTLSLKSKDCNSNILSVSSLTSTSSTSIPDPGASDLLEEHLFSPIPIVQNELLSPLRDFEDIKSLWVKIELSFLSRIPGQDPPEPPPTKAECREVSVKHRRQQSPASIPAEKNPSKSKRKHKSEHCDVMSGGKKLRLDKDT--LLLPPCISPIHNHKVSSTKDS--LKKQPRKKDDKLLPPLLSPLSVEPVGR--------------------------PRRSSE--CSSLS----QEG--------STSTIPNNLPSSRTIPASSSSSSSSSSHKHRKGENKAFSHSKTSTEEDSHSKPSGGFHGNGQSDADLWSNPSALTMEHMEPRRPKLTFNSTVHSADYYMQEAKKLKHKADALMDKFGKAVNYADGALSFIECGNAMERDPLEAKSPYTMYSETVELIRYAMRLKNFTSHSATIAEKKLAVLCNRCLSLLYLRMFKLKKDHAMKYSRSLMEYFKN-SAKSSQAPSPWGANGKSTGTPSPMSLSPSPVSSVSSSAGAMGSSSASGSVAIPQRIHHMAASHVNITNNILRSYEHWETADKLAQESQEFFVELDSVMEPLTQHSSMTELVRYIRQGLHWLRLEAHLL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *******:****************:*****.*****::****:**:******* ****************.*****:**:.**.*.*********.**.* .* .:..*:** :. . * :*.:: ***: .* .*:::*.::..*. :*.:..*..* . ::*::.: : ::: .. : :: .: :* * . .*:.* *: .::. : *: .:** *.: :...***.::***. ****. .** **:** :* ****************..: ** ***.:*: :.:..:.** *** *.*:..:* *:**:*: *:.****..*..******** ***:*.*:. :: . *:.:.:** *******:****:* : **.**.**:...:* :*. . .* ::. .****************:***::***.*.*.*.******* .*******::**..:**::* * :: . * * . . : * *...: . * ****.*** *****:*:. ** *::*: * * .:: : .. :*: *********:.:* :*..**:*. :.****** . * **: *.*... *..******. ::. ..:***:***.**:***:*****:**:*:.::* ** ** ** . ***: . *::*:* . ... * ** *** * :*.*:******.*: *.*****:*.:***:**:.. .*:*.: :*.: * :** .* ..** ..*.*****. . ** **:. * ******** ** ..*::. :: *:*::**:** ****. :* * *:*:. *:::. :** :* *:.* :: * .*: : ::: . .* : :.*:* . .. : *: ...: : *: . *: . : *******:.:**.**:***************::**********.**** **************************:*********:* *: .:******* ******************************: ::* :* **** .***.* ***:**. **.:.: . .. .*.*:****************.*:**.****: ****:::.:*** :**::* *********:****:**** ***::****", "identical_positions": 618, "similar_positions": 367, "identity": "45.85%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-193", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43504-1", "uniprot_id": "LTOR5_HUMAN", "id": "O43504-1", "name": "Ragulator complex protein LAMTOR5", "aln": "-----------------------------------------------------------------MEATLEQH------LEDTMKNPSIVGVLCTDSQGLNLGCRGTLSDEHAGVISVLAQQAAKLTSDPTDIPVVCLESDNGNIMIQKHDGITVAVHKMAS---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZF11-1", "uniprot_id": "D3ZF11_RAT", "id": "D3ZF11-1", "name": "Ragulator complex protein LAMTOR5", "aln": "MPANAGSVVVAMSFRKECERGATMNLFPLETPSARPPRSSHVTEACCEGGSVLPRGLGLGRTVYGMEATLEQH------LEDTMKNPSIVGVLCTDSQGLNLGCRGTLSDEHAGVISVLAQQAAKLTSDPTDIPVVCLESDNGNVMIQKHDGITVAVHKMAS---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D1L9-1", "uniprot_id": "LTOR5_MOUSE", "id": "Q9D1L9-1", "name": "Ragulator complex protein LAMTOR5", "aln": "-----------------------------------------------------------------MEATLEQH------LEDTMKNPSIVGVLCTDSQGLNLGCRGTLSDEHAGVISVLAQQAARLTSDPTDIPVVCLESDNGNIMIQKHDGITVAVHKMAS---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58G5Z4-1", "uniprot_id": "A0AC58G5Z4_DANRE", "id": "A0AC58G5Z4-1", "name": "Ragulator complex protein LAMTOR5", "aln": "--------------------------------------------------MMEKR---WSKSFLMTPDTLAPFYWIFLWLLIMMKNPAIVGVLCTDAQGHNLGCRGSLSDEHGGVVSVLAKQAASLTKDATDCPTVCLESDCGNILVRRHGTITLAVHKMAS---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O96824-1", "uniprot_id": "O96824_DROME", "id": "O96824-1", "name": "Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5", "aln": "-----------------------------------------------------------------MEQQLEKV------LAEIAARQDTVGALLANRQGLCLGTKGDIDPNVSGIGMAISEQVAKLELNATAPATICLYSGNKRCVIQKDGEITGVIFKQPTGTSATAPSN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * . **.* :: ** ** :* :. : .*: .:::*.* * :.* ..:** *. . ::::.. ** .:.* .: ", "identical_positions": 21, "similar_positions": 33, "identity": "12.28%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-20", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QYC5-1", "uniprot_id": "G37L1_RAT", "id": "Q9QYC5-1", "name": "G protein-coupled receptor 37-like 1", "aln": "MRWLWPLAVSLAVVLAVGPSEVSGAATLSLGGHRAKVQEQQSRPRRGTKDEGPKEVQHYVPEEWAEYPKPIHPAGLQPTKPLVATSPNPDKDGATSESGQELRTNLTGTPSQRLQIQNPLYPVTESSYSAYAVMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMMLAVPELLLWQLAQEPTPTMGT-VDSCIMKPSADLPESLYSLVMTYQNARMWWYFGCYFCLPILFTVTCQLVTWRVR--------GPPGRKPECRAGRHEQCESQLNSTVVGLTVVYAFCTLPENICNIVVAYLSTELTRQTLDLLGLINQFSTFFKGAITPVLLLCICRPLGQAFLDCCCCCCCEECGGASDSSATVSADSKLKAEVSS---------------------SIYFHKPRESPPLLPLGTPC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JG2-1", "uniprot_id": "G37L1_MOUSE", "id": "Q99JG2-1", "name": "G protein-coupled receptor 37-like 1", "aln": "MRWLWPLAVSLVVVLTVGLSGVSGAATSSLGGHRAKVQEQQSRPRRGTKDEGPKEVQHYVPEEWAEYPKPIHPAGLQPTKTLEATSPNPDKDGATPGNGQELRVNLTGTPSQRLQIQNPLYPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMMLAVPELLLWQLAQEPAPTAGT-VDSCIMKPSADLPESVYSLVMTYQNARMWWYFGCYFCLPILFTVTCQLVTWRVR--------GPPGRKPECRAGRHEQCESQLNSTVVGLTVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLINQFSTFFKGAITPVLLLCICRPLGQAFLDCCCCCCCEECGGASDSSATVSADSKLKAEVSS---------------------SIYFHKPRESPPLLPLGTPC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60883-1", "uniprot_id": "G37L1_HUMAN", "id": "O60883-1", "name": "G protein-coupled receptor 37-like 1", "aln": "MRWLWPLAVSLAVILAVGLSRVSGGAPLHLGRHRAETQEQQSRSKRGTEDEEAKGVQQYVPEEWAEYPRPIHPAGLQPTKPLVATSPNPGKDGGTPDSGQELRGNLTGAPGQRLQIQNPLYPVTESSYSAYAIMLLALVVFAVGIVGNLSVMCIVWHSYYLKSAWNSILASLALWDFLVLFFCLPIVIFNEITKQRLLGDVSCRAVPFMEVSSLGVTTFSLCALGIDRFHVATSTLPKVRPIERCQSILAKLAVIWVGSMTLAVPELLLWQLAQEPAPTMGT-LDSCIMKPSASLPESLYSLVMTYQNARMWWYFGCYFCLPILFTVTCQLVTWRVR--------GPPGRKSECRASKHEQCESQLNSTVVGLTVVYAFCTLPENVCNIVVAYLSTELTRQTLDLLGLINQFSTFFKGAITPVLLLCICRPLGQAFLDCCCCCCCEECGGASEASAANGSDNKLKTEVSS---------------------SIYFHKPRESPPLLPLGTPC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TED3-1", "uniprot_id": "A0A8N7TED3_DANRE", "id": "A0A8N7TED3-1", "name": "", "aln": "-----MMLSALLVLMALAASIQAENRALET-----KMEPSSSHPYYSSSSSSS------VHEAGRAGHAPRVPRGSK-SRPRERSEPQPPRAHPEADTFFTTPRPFSGA----LRLHNPLFPVTDESYSAYAVLLLALIVFSVGIVGNLALMCIVWHNYYLKSTWNCVLASLAFWDFMVLFFCLPVVIFNELTKRRLMGDLSCRAVPYVEVASLGVTTFTLCALSIDRFHTVTSGQSRPRQGESCQSILAKLSVIWLGSLLLAAPELLLWRLEQDGSPQSGLPVDACRPQPSADLPDALLSLVLTYQHARMWWTFGCYFCLPLLFTGACHLLTRHVSEDEKTLRSSSTSSSSSSSSIKKRRRERQLTRTVVALAFIYAICSLPEYIWNIVLAYVGVDVGVATQALLALIGQFLLFVRAGATPVVLLCICRSLGQAFMD-CCCCCCEECFSDPSSSCTTSSVSTNATAVSSPPASPVSMQEDKLKIVSGTSPAVFFDKVKESPAELIIGTPC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* *::::. * : . : : ..*:. .:... . * * * * * : ::. :.*:* : . . ::*: *:::***:***:.******::****:**:*******::******.*****:**.:*****:***:*******:*****:**:**:**:******::**:*******:****.*****..** .: * * ********:***:**: **.******:* *: :* * :*:* :***.**::: ***:***:***** ********:*** :*:*:* :* .... .... : ::.: * **. ***.*:.:**:*:*** : ***:**:..:: * **.**.** *.:.. ***:******.*****:* ********* . ..:*.: .: .. : *** :::*.* :***. * :****", "identical_positions": 227, "similar_positions": 141, "identity": "44.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-202", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P68543-1", "uniprot_id": "UBX2A_HUMAN", "id": "P68543-1", "name": "UBX domain-containing protein 2A", "aln": "-MKDVDNLKSIKEEWVCETGS-DNQPLGNNQQSN---CEYFVDSLFEEAQKVSSKCVSPAEQKKQVDVNIKLWKNGFTVND-DFRSYSDGASQQFLNSIKKGELPSELQGIFDKEEVDVKVEDKKNEICLSTKPVFQPFSGQGHRLGSATPKIVSKAKNIEVENKNN-LSAVPLNNLEPITNIQIWLANGKRIVQKFNITHRVSHIKDFIEKYQGSQRSPPFSLATALPVLRLLDETLTLEEADLQNAVIIQRLQKTAS-FRELSEH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99KJ0-1", "uniprot_id": "UBX2A_MOUSE", "id": "Q99KJ0-1", "name": "UBX domain-containing protein 2A", "aln": "-MKEVDNLDSIKEEWACETGPPDSQPLNDNQQKD---CEYFVDSLFEEAGKAGAKCLSPTEQKKQVDVNIKLWKNGFTVND-DFRSYSDGASQQFLNSIKKGELPSELWGIFDKEEVDVKVEDKKNEVCMSTKPVFQPFSGQGHRLGSATPRIVSKAKSVEVDNKST-LSAVSLNNLEPITRIQIWLANGERTVQRFNVSHRVSHIKDFIEKYQGSQRSPPFALATALPFLRFLDETLTLEEADLKNAVIIQRLQKTAEPFRKL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7EY86-1", "uniprot_id": "E7EY86_DANRE", "id": "E7EY86-1", "name": "", "aln": "MMKNIDSRERHEDDTWCEGAQNEEEEEEEDEEASPIRSSFSVEDLLDEVEKISSVASS----GKKVEIVVRLWKNGFTLNDEDLRSYTQEENQEFLEAIKKGELPLELEGRAEDEELEVNVEDMKDEVYVPKKKIFHPFTGRGYRLGSVAPRVVARSRSIHEDCSGPPVPAVELNEDLPVTSLQIWLADGRRLVQRFNLCHRISDVQRFVEQAQIT--DTPFILTTSLPFRELTDEAQSLEEADLANAVIVQRPVNTHAPFGHS---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **::*. . ::: ** . :.: :::: . ..: *:.*::*. * .: . * *:*:: ::*******:** *:***:: .*:**::******* ** * :.**::*:*** *:*: :..* :*:**:*:*:****.:*::*::::.:. : .. :.** **: *:* :*****:*.* **:**: **:*.:: *:*: * : ..** *:*:**. .: **: :****** ****:** :* * . ", "identical_positions": 103, "similar_positions": 97, "identity": "38.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-203", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86UD5-1", "uniprot_id": "SL9B2_HUMAN", "id": "Q86UD5-1", "name": "Sodium/hydrogen exchanger 9B2", "aln": "---------------------------------MGDEDKRITYEDS-------EPSTGMNYTPSMHQEAQEETVMKLK----------------------------------------------------GIDANEP--TEGSILLK---SSEKKLQETPTEANHVQRLRQ---------------------------------------------------------------------MLACPPHGLLDRVITNVTIIVLLWAVVWSITGSECLPGGNLFGIIILFYCAIIGGKLLGLIKLPTLPPLPSLLGMLLAGFLIRNIPVINDNVQIKHKWSSSLRSIALSIILVRAGLGLDSKALKKLKGVCVRLSMGPCIVEACTSALLAHYLLGLPWQWGFILGFVLGAVSPAVVVPSMLLLQGGGYGVEKGVPTLLMAAGSFDDILAITGFNTCLGIAFSTGSTVFNVLRGVLEVVIGVATGSVLGFFIQYFPSRDQDKLVCKRTFLVLGLSVLAVFSSVHFGFPGSGGLCTLVMAFLAGMGWTSE-------------KAEVEKIIAVAWDIFQPLLFGLIGAEVSIASLRPETVGLCVATVGIAVLIRILTTFLMVCFAGFNLKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEDYGMD--VLTVAFLSILITAPIGSLLIGLLGPRLLQKVEHQNKDEEVQGETSVQV------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5BKR2-1", "uniprot_id": "SL9B2_MOUSE", "id": "Q5BKR2-1", "name": "Sodium/hydrogen exchanger 9B2", "aln": "---------------------------------MEDEDKTAECQHS-------KPPTGITHEAPPHHELQEERVMSLR----------------------------------------------------GTDRSEP--TEGSNLLT---SGEKKPQDSPTEPNGLQSLRR---------------------------------------------------------------------FLACPPRGCLARVITNGTMVVLLWAMVWSVTGPECLPGGNLFGIIILFYCSITGGKLFGLIKFPTLPPLPPLLGMLLAGFLLRNIPVINDSVRIQHKWSSSLRSIALSVILVRAGLGLDSKALRKLKGVCVRLAMGPCIVEACASAILSHFLMGLPWQWGFILGFVVGAVSPAVVVPSMLLLQEGGYGVGKGIPTLLMAAGSFDDILAITGFNTCLGVAFSTGSTVFNIFRGILEVVIGVAAGSFLGFFIQYFPSRDQDNLVWKRAFLVLGFAVLAVFSSVYFSFPGSGGLCTLVMAFLAGMRWTDK-------------KSEVEKVIAVTWDVFQPLLFGLIGAEVSIVSLRAETVGLCVATLSIAVLIRILTTFLMVCFAGFNIKEKIFISFAWLPKATVQAAIGSVALDTARSHGEKQLEDYGMD--VLTVAFLAILITAPIGSLLIGLLGPRVLQKSEHR-TEEEVQGETSAHIQRKPEDSITEA-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2B6Y3-1", "uniprot_id": "A0A8M2B6Y3_DANRE", "id": "A0A8M2B6Y3-1", "name": "", "aln": "--------------------------MEQKCSAMEDVQSRPHSAHSLYSQRTEDATSALGNHAEHHLTVSQTVLVVPK----------------------------------------------------RPESPNPSMTEETIYVPRPVSAVDACTNTDPPYECCPWLRR---------------------------------------------------------------------LCPCPPRGMLAAIITKVTMAAVLFGVVWSITEKECLPGGNLFGIVTLFICSVAGGKLFGRIRLPRLPPVPPLLGMLLAGFILRNIPVVTDAVYIDVRWSSSLRNIALGVILVKAGLELDSKALKKLKAVCLRLSMFPLIFEAATMAVMSYLILGLPWIWGFILGFVLGAVTPAVVVPSMLLLHRQGYGLEQGIPTLLMAACSVDDIIAITCFTTCLGIAFATGSVWLNVLRGPLEVLGGAVTGVALGFFLHYFPSRDQRNLVLKRSFLVLGLSVFALFGSNVAGIPGAGGLCTLVLAFVAGIGWGRA-------------KASVEAVVERFWLVFQPLLFGLIGAEIVISSLELTTVFLGIAALFIGLTVRLLVTFIVVLRAGFNLKEKIFVTLAWMPKATVQAAIGSTALDMARSKQDLELQKYGMD--VLTVAVLSIIITAPIGALLISLLGPRLLQKPKNP-EWAVSQGALSASGTPVTYESAL---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q4ZJI4-1", "uniprot_id": "SL9B1_HUMAN", "id": "Q4ZJI4-1", "name": "Sodium/hydrogen exchanger 9B1", "aln": "---------------------------------MHTTESKNEHLEDE------NFQTSTTPQSLIDPN-----------------------------------------------------------------------------NTAQEETKTVLSDTEEIKP---QTKKE-------------------------------------------------------------------TYISCPLRGVLNVIITNGVILFVIWCMTWSILGSEALPGGNLFGLFIIFYSAIIGGKILQLIRIPLVPPLPPLLGMLLAGFTIRNVPFINEHVHVPNTWSSILRSIALTIILIRAGLGLDPQALRHLKVVCFRLAVGPCLMEASAAAVFSHFIMKFPWQWAFLLGFVLGAVSPAVVVPYMMVLQENGYGVEEGIPTLLMAASSMDDILAITGFNTCLSIVFSSGGILNNAIASIRNVCISLLAGIVLGFFVRYFPSEDQKKLTLKRGFLVLTMCVSAVLGSQRIGLHGSGGLCTLVLSFIAGTKWSQE-------------KMKVQKIITTVWDIFQPLLFGLVGAEVSVSSLESNIVGISVATLSLALCVRILTTYLLMCFAGFSFKEKIFIALAWMPKATVQAVLGPLALETARVSAP-HLEPYAKD--VMTVAFLAILITAPNGALLMGILGPKMLTRHYDPSKIKLQLSTLEHH-------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C0X2-1", "uniprot_id": "SL9B1_MOUSE", "id": "Q8C0X2-1", "name": "Sodium/hydrogen exchanger 9B1", "aln": "---------------------------------MSEHDVES-NKKDD------GFQSSVTVEMSKDPDSFHEETVEPKPELKEPE----------------------------PKEPEPKEPERKEPERKEPERKEPERKEPERKVPGRRETQTKETQTTEIERKETKKKRG-------------------------------------------------------------------TNSYCPPQGTINKTITDGAALIALWTLLWALIGQEVLPGGNLFGLVVIFYSAFLGGKILEFIKIPVVPPLPPLIGMLLAGFTIRNVPIIYEFVHIPTTWSSALRNTALTIILVRAGLGLDPQALKHLKGVCLRLSFGPCFLEACSAALFSHFIMNFPWQWGFLLGFVLGAVSPAVVVPNMLMLQENGYGVEKGIPTLLVAASSMDDIVAITGFNTFLSIVFSSGSVISNILSSLRDVLIGVLVGIVMGVFVQYFPSGDQERLTQRRAFLVLSMCISAVLGCQHIGLHGSGGLVTLVLSFMAAKRWAEE-------------KVGIQKIVANTWNVFQPLLFGLVGTEVSVESLESKTIGMCLATLGLALSVRILSTFVLMSFANFRFKEKVFIALSWIPKATVQAVLGPLALETARVMAP-HLEGYAKA--VMTVAFLAILITAPNGALLIGILGPKILEQSEVTFPLKVELSNFHH--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VM74-1", "uniprot_id": "Q9VM74_DROME", "id": "Q9VM74-1", "name": "", "aln": "--------------------------MFSSHKKMTATGEPEAREDPSVGGAPATITTPTTIIAPTPIPVPSDVPMPNSNGSGNGAG--NHRSTIVIESQPKRRVSIISDPPMIGGNGGLGTGYDNPAYEQNPRRKISQTSTHSHTDIGPARRKSILKDTAPHDNESDRVSTHSYENYRQNALDVLNAKYNGHQMGHNGGGSSNGGANYVEESWMYNFCLKCRGEEPSASWEPPFWQKIFPYPLCPTFRTVSRLISIILIGVLIWVTAFVIIGDSAAPGGQLFGLVVLTVAANFGGYLISLT------TLPRLIGMLLVGILFQNVGWADIDGDFS-KVTAHLRKFALTIILTRAGLEMEPEAFKKVYKTILKLGIIPWCVEAVVMAVMSHFLLDLPWIWAFLLGSIIAAVSPAVVVPCLFRLRTKGYGVAKGIPTLVVAVAGVDDALSVAIFGIISTVMFSDKGLAYQIAQAPVCILGGLGFGVVWGSLARIFPEKGDAYVVPLRTLLLFTGGLMAIYGSEELGFEGAGPLAVVFSAFVSNLFWCKDGW--------DVEDNPVSTAFEIFWMIFEPILFGLTGATIKIRELDSHTVSIGAACIFTGAILRILTTAGIAFGDRLNTKEKFFVGLSWMAKATVQAALGPVALKHLGDDATEEERNWANI--VQTICVFSIVLTAPLGAIMISVTGTKLLTKTKQPQDLSGWRRSHRPSIRDISIIDEEEEREDPEIPEDKETHDNTLNNAHIPSISYTYNT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4K6G5-1", "uniprot_id": "A0A0B4K6G5_DROME", "id": "A0A0B4K6G5-1", "name": "", "aln": "MSSDSDILDVVAGSEGPPLQAFRSSNPFEDSYQMSSCQQDFERDRDANLTPLHMLRRASETVTASILEPEKEHLLGDKPQVPPRAHGSTAPSAIEAKRSRQQPNQWQLQQQQQPSSNNNNTKRALAPGDNMTQGAAPQDSQGDILPTRPLHTKLDIQKIPEDEAGADATQNAATIILTPTSLNLTNTTTQNVAANNAGNSSTTTSTNTN-----YGPGSVSGYPTPNATPGDEYKGPKWWLYIRSHWVNTSELVALLAIFLGLWAMGWVLLPEYSQPPTVIMRIAFLFVGAQISGILVTFVH------LPDMLGMLFFGVLYANLGLAN--FEGYQKFELFLREMALINIMLLAGLGLDGDAFKRLWFMILRLTLLPTIVEVAAIAGLANLTLSMPWLWGIALGLVITAVSPNVVVTVMLKLKEDRLGLNSGIHTLIYAMTTCNDVVAIFMFGVIISVIFSTTSLTQQVLQGPIGIGIGLVFGYLYGSMLQYLPSRNATYANGLRFVLTILGGTIAVMGSRVIGYTSAGALGCVTTAFIARIGWRREETRLTPQQLQAQQIASVPKRLDLMWKFLKPVSFALIGKEINFNVLQGHVIGYGALLVLVGSLFRLAFAYLSTYGGNLSRKERAYITISGFPKATVQAALGPVALDMARAASVASPEQLALAGNLLIISVLAIIFTAPLGAILMLRLAPYWLKHGDAVEAVDSPTTPIAPTLGSTNSSKGT---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . :: :: : : * :: : : : .* :. :* ::***: *. *: **. ** *: *** :: .*:::: .:* . * .*. * :: : :** *.: ** :: **:* ***. :: *: *: .*: **: * :* ::: * : *: . : . : . * * : : :*. . * .* : *: .. . .:* * : :*:: * : . * .::*: *.* * : . * : : . .*: : : **: :: :: :.******.:*. **. . . : :..::*::*** *:::: .. * : ", "identical_positions": 76, "similar_positions": 125, "identity": "10.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-205", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O15344-1", "uniprot_id": "TRI18_HUMAN", "id": "O15344-1", "name": "E3 ubiquitin-protein ligase Midline-1", "aln": "METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATN-ESVESITAFQCPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMTSAEKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQANVV-------------SLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPHLRRVGILLDYDNGSIAFYDALNSIHLYTFDVAFAQPVCPTFTVWNKCLTIITGLPIPDHLDCTEQLP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P82458-1", "uniprot_id": "TRI18_RAT", "id": "P82458-1", "name": "E3 ubiquitin-protein ligase Midline-1", "aln": "METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATN-EPVESINAFQCPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMSSAEKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQERRQIIGTKIKEGKVMRLRKLAQQIANCKQCIERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPTIREELCTASYDTITVHWTSDDEFSVVSYELQYTIFTGQANVV-------------SLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFMVKAINQAGSRSSEPGKLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDESSSKKSHTPERFTSQGSYGVAGNVFIDSGRHYWEVVISGSTWYAIGLAYKSAPKHEWIGKNSASWALCRCNNNWVVRHNSKEIPIEPAPHPRRVGILLDYDNGSIAFYDALNSIHLYTFDVALAQPVCPTFTVWNKCLTIITGLPIPDHLDCTEQLP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70583-1", "uniprot_id": "TRI18_MOUSE", "id": "O70583-1", "name": "E3 ubiquitin-protein ligase Midline-1", "aln": "METLESELTCPICLELFEDPLLLPCAHSLCFNCAHRILVSHCATN-EPVESINAFQCPTCRHVITLSQRGLDGLKRNVTLQNIIDRFQKASVSGPNSPSETRRERAFDANTMSSAEKVLCQFCDQDPAQDAVKTCVTCEVSYCDECLKATHPNKKPFTGHRLIEPIPDSHIRGLMCLEHEDEKVNMYCVTDDQLICALCKLVGRHRDHQVAALSERYDKLKQNLESNLTNLIKRNTELETLLAKLIQTCQHVEVNASRQEAKLTEECDLLIEIIQQRRQIIGTKIKEGKVIRLRKLAQQIANCKQCLERSASLISQAEHSLKENDHARFLQTAKNITERVSMATASSQVLIPEINLNDTFDTFALDFSREKKLLECLDYLTAPNPPAIREELCTASYDTITVHWTSEDEFSVVSYELQYTIFTGQANVVNVACDGTCLLGSAGLCNSADSWMIVPNIKQNHYTVHGLQSGTKYIFTVKAINQAGSRSSEPGKLKTNSQPFRLDPKSAHRKLKVSHDNLTVERDESSSKKSHAPERFAGQGSYGVAGNVFIDSGRHYWEVVTSGSTWYAIGLAYRSAPKHEWIGKNAASWALCRCHNHWAVRHDGKETPIAPAPHLRRVGVLLDYDNGSIAFYDALSSVHLHTFHAALAQPVCPTFTVWNKCLTIVTGLPIPDHLDCTEQRP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3AWB4-1", "uniprot_id": "A0A8M3AWB4_DANRE", "id": "A0A8M3AWB4-1", "name": "E3 ubiquitin-protein ligase Midline-1", "aln": "MDTLESELTCPICLELFEDPLLLPCAHSLCFHCAHRILTSHCAAFDESSKPPSAFQCPTCRYVITLDQQGLDGLKRNVTLQNIIERFQKASLSGPNSPTETRKQISPSA-MSSACEAVQCQFCEQDPPQEAVKTCVTCEVSYCQECLRATHPNKKPFTGHRLTEPVPDARLRGLACPEHGEEKVNMYCITDEQLICSLCKLVGHHREHQVASLGERYDKLKQMLDSNLSNLIKRNSELENLMAKLIQTCQHVEHNAAHQESKLTEECDTLINIVQQRRQIIGTKIKEGKVVRLRKLAQQIANCKQFVERSSSLIIQADQALKETDHARFLQMAKSISERVSMATASSQVLIPEINLNDTFDAFALDFSREKKMLEGLDYLTAPNAPTIREELCTASHDTITVHWTSEDEFSVVSYELQYTISTGQANVV-------------SLCNSMDSWMIVPNIKQNHYTVHGLQSGTKYIFIVKAMNQAGSRSSPPGQLKTNSQPFKLDPKSAHRKLKVSHDNLTVERDEASSMKSHAQDRFGGTGNYGVTGNVYIDSGRHYWEVLIGGSTWFAIGIAYKSAPKHGWVGKDSTSWVLSRCNTSWAVRHNSKEFPIEPSPHMRRLGVLLDYDSGSLAFYDAAGTQHLYTFDIAFSQPICPVFSVWNKCLTVLTGLPIPDHLEISDPHD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*****************************:******.****: *. :. .********:****.*:***************:******:******:***:: : .* ::.* * ****:***.*:*************:***:************** **:**:::*** * ** :*******:**:****:******:**:****:*.******** *:***:******:***.*:*********** **::**:******* **:*:*:**************:************** :***:*** **:::***.******* **.*:************************:**********:** ********.*:*********:*********:************** ******* .**** *************************** ***:******** **:********:***********************:** ***: :** . *.***:***:**********: .****:***:**:***** *:**:::**.*.**:. *.***:.** ** *:** **:*:*****.**:***** .: **:**. *::**:**.*:*******::*********: :: ", "identical_positions": 515, "similar_positions": 110, "identity": "75.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-210", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ULI0-1", "uniprot_id": "ATD2B_HUMAN", "id": "Q9ULI0-1", "name": "ATPase family AAA domain-containing protein 2B", "aln": "MVNTRKSSLRLLGSKSPGPGPGP--GAGAEPGATGGSSHFISSRTRSSKTRAASCPAAKAGG---SGGAGVTLDEARKVEVDGSLSDSHVSPPAKRTLKQPDSVCKDKSKS-RSTGQREEWNLSTGQARLTSQPGATLPNGHSGLSLRSHPLRGEKKGDGDLSCINGDMEVRKSCRSRKNRFESVNQSLLFDQLVNSTAEAVLQEMDNINIRRNRRSGEVERLRMWTDTEFENMDMYSRVKRRRKSLRRNSYGIQNHHEVST----------------EGEEEESQEEDGDIEVEEAE-----GEENDRPYNLRQRKTVDRYQAPPIVPAHQKKRENTLFDIHRSPARRSHIRRKKHAIHSSDTTSS-DEERFERRKSKSMARARNRCLPMNFRAEDLASGILRERVKVGASLADVDPMNIDKSVRFDSIGGLSHHIHALKEMVVFPLLYPEIFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKKVAFFMRKGADCLSKWVGESERQLRLLFDQAYLMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDNRGEIVVIGATNRLDSIDPALRRPGRFDREFLFNLPDQKARKHILQIHTRDWNPKLSDAFLGELAEKCVGYCGADIKALCTEAALIALRRRYPQIYASSHKLQLDVSSIVLSAQDFYHAMQNIVPASQRAVMSSGHALSPIIRPLLERSFNNILAVLQKVFPHAEISQSDKK-EDIETLILEDSEDENALSIFETN----CHSGSPKKQSSSAAIHKPYLHFTMSPYHQPTSYRPRLLLSGERGSGQTSHLAPALLHTLERFSVHRLDLPALYSVSAKTPEESCAQIFREARRTVPSIVYMPHIGDWWEAVSETVRATFLTLLQDIPSFSPIFLLSTSETMYSELPEEVKCIFRIQYEEVLYIQRPIEEDRRKFFQELILNQASMAPPRRKHAALCAMEVLPLALPSPPRQLSESEKSRMEDQEENTLRELRLFLRDVTKRLATDKRFNIFSKPVDIEEVSDYLEVIKEPMDLSTVITKIDKHNYLTAKDFLKDIDLICSNALEYNPDKDPGDKIIRHRACTLKDTAHAIIAAELDPEFNKLCEEIKEARIKRGLSVTSEQINPHSTGARKTETRVEEAFRHKQRNPMDVWHNSANKCAFRVRRKSRRRSQWGKGIIKKRKVNNLKKDEEDTKFADYENHTEDRKLLENGEFEVSTDCHEENGEETGDLSMTNDESSCDIMDLDQGQRLNNGAGTKENFASTEEESSNESLLVNSSSSLNPEQTSRKETFLKGNCLNGEASTDSFEGIPVLECQNG-KLEVVSFCDSGDKCSSEQKILLEDQSKEKPETSTENHGDDLEKLEALECSNNEKLEPGSDVEVKDAELDKEGASKVKKYRK-LILEQAKTTSLELVPEEPSEPVPPLIVDRERLKKLLDLLVDKSNNLAVDQLERLYSLLSQCIYRHRKDYDKSQLVEEMERTVHMFETFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9Q166-1", "uniprot_id": "E9Q166_MOUSE", "id": "E9Q166-1", "name": "", "aln": "MVNTRKSSLRLLGSKSPGPGPGPGAGAGAEPGATGGSSHFISSRTRSSKTRAASCPAAKAGG---SGGA---LDEARKAEVDGSLSDSHVSPPAKRTLKQPDSVCKDKSKS-RSTGQREEWNIPSGQTRLTSQPGATLPNGHSSLSLRSHPLRGEKKGDGDLSCINGDIEVRKSCRSRKNRFESVNQSLLFDQLVNSTAEAVLQEMDNINIRRNRRSGEVERLRMWTDTEFENMDMYSRVKRRRKSLRRNSYGIQNHHEVST----------------EGEEEESQEEDGDIEVEEAE-----GEENDRPYNLRQRKTVDRYQAPPIVPAHQKKRENTLFDIHRSPARRSHIRRKKHAIHSSDTTSS-DEERFERRKSKSMARARNRCLPMNFRAEDLASGILRERVKVGASLADVDPMNIDKSVRFDSIGGLSHHIHALKEMVVFPLLYPEIFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKKVAFFMRKGADCLSKWVGESERQLRLLFDQAYLMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDNRGEIVVIGATNRLDSIDPALRRPGRFDREFLFNLPDQRARKHILQIHTRDWNPKLSDAFLGELAEKCVGYCGADIKALCTEAALTALRRRYPQIYASSHKLQLDVTSIVLSAHDFYHAMQNIVPASQRAVMSSGQALSPIIRPLLERSFNNILAVLQKIFPHAETSQNFVAGSDLNCPSLEISSDYEETSIPEVKSSGKCFLG--KKLCSKDSQGSTFVHLNFNMAFGPTSYRPRLLLSGERGSGQTSHLAPALLHTLERFSVHRLDLPALYSVSAKTPEESCAQIFREARRTVPSIVYMPHIGDWWDAVSDTVRATFLTLLQDIPSFSPIFLLSTSETMYSELPEEVKCIFRIQYEEVLYIQRPIEEDRRKFFQELILHQASMAPPRRKHTALRAMEVLPLALPSPPRQLSESEKNRMEDQEENTLRELRLFLRDVTKRLATDKRFNIFSKPVDIEEVSDYLEVIKEPMDLSTVITKIDKHNYLTAKDFLQDIDLICSNALEYNPDKDPGDKIIRHRACTLKDTAHAIIAAELDPEFNKLCEEIKEARIKRGLSVTAEQITPHGAGARKTETRVEEAFRHKQRNPMDAWHNSANKCAFRVRRKSRRRSQWGKGIIKKRKVNNLKKDEEDTKFTDYD-HTEDRKLLENGEFEVSTDCHEENGEETGDLSMTNDESSCDIMDMDQGQRLNSGAGTKENFASTEEESSNESLLVHSSSSLNPEQTSKKEPFLKGTCLNGEASTDSSEGIPVLECQNGRVLEVVPLPDGGEKSSSEQKIALEEQLKDKPETWNENRGDAAEKLEVLECSSSEKPEPGPDAEGKETELDREGASKVKKYRK-LLLEQAKPTNLELVPEEPSEPAPPLVVDHERLQKLLDLLVDKSNNLTVDQLERLYSLLSQSIYRHRKDYDKSQLVEEMERTVHMFETFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB13A7R6-1", "uniprot_id": "A0AB13A7R6_DANRE", "id": "A0AB13A7R6-1", "name": "ATPase family AAA domain-containing protein 2", "aln": "MVNTRKSSE-------------------HKP-----SSPFISGRTRSSQRNNPNLDEHNSRVRKRETPAAYSLRQPKEPSSDANSSSPRLSPPPKRTRRQTPPSSTDTSPSPQSKGQRGSWTMSKHCTRLSTG---ALQNGHT---IGRMSLRGDSTSGGDHARMNGHVELKRSRRVRKSQFEHLNQSLLFDQLVNSTAEAVLQEMDNISSIRQSR--EVERLRMWTDTELENMDMYSRVKRR-KSLRRNTYGMQSHHKVMSKSKDPEEEEGTEESNEEGEEDEDVEADDDDEDDEGDEAEEAGEENDRPYNLRQRKTVQRYEAPPIEPVNRKQSKGSLFDTHRSPARRSHIRIKKHAIHSSESTSSSDEERFERRKSKSMSRARNRCLPMNLRAEDLASGVLRDRVKVGASLADVDPMNLDTSVKFDSVGGLTHHIQSLKEMVVFPLLYPQVFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDRKVSFFMRKGADCLSKWVGESERQLRLLFDQAYLMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLALMDGLDSRGEIVVIGATNRLDSIDPALRRPGRFDREFLFNLPDKKARKHILEIHTRDWSPKLAEPFIDELAERCVGYCGADIKALCTEAALAALRRRYPQIYGSSQRYQLDVASIVLGPQDFGRALRSIVPAGQRALAPPGQALSCVLKPLLEPTLNQTLACLTRVFPHAELLHREHTHDSDNHLLVEDSYSEDEECLGASS-IYETQSGSPKKAAS-CTTHKPFLHFTTSAYQQPTSYRPRLLLTGPQGAGQSTHLAPALLHHLEKFTVHRLDLPTLYSVSAKTPEESCAQVFREARRCVPSIIYMPHISAWWEAISETVKSSFLMLLQDVPSFTPLLILATAESVYQQLPDELKCIFSRSYGEVFCLSMPGEEARRKFFSDLILVQAAKAPPRR-RKSACALEVLTLSEDPGPRQLSAEEQRRLEEQEENTLRELRLFLRDVTKRLATDKRFQIFSKPVDIEEVSDYLEVITQPMDLSAIMMKIDKHKYMVAKDFLADIDLICSNALEYNPDKDPGDKIIRHRACSLKDTAHAMIASELDPEFDRMCEEIKESRRKRAPQTAPQPPVTPSTVATRKPMGEEAGLSSSQGD------GVDKHCSNNIKRKFRRRPIWGRGIIRKKKSYKKEEAEEDDEPEEEE-GAEDSTVMAQG-----------------DACLTLDESSCDTMELHPEKQPLQANG---HVLSTEEENSCEPTAARDAQ--GQEEAPSEEPTVAPTVP------------APQECVNGNESMDSVYSEAPDKDTIKR-----DALEQKPTEHKEASG--------TECSTGEN-TRTAEAVASDGDHEKEGSSKGKECGKGLSEVQAEEPAVRLQEAVQLPPPPDLVVDHQRLKALLEQAVVKSEGFSVDHLERVFSALSQCIYQHRRDYDKTRLIEAMERQVEHFETFL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******** :* ** ***.*****: . .. :: . * * :.:: . *.. *..::***.*** :*. . ..*.* * :*.*** .*.:.. :**:: :* ***: : .***:....** : :**.:*:::* * **.:** :************************. *: * ************:************ ******:**:*.**:* : ****:*. * *.* * :*.: ****************:**:**** *.::*: :.:*** *********** ********::*** *************:**********:********:**:***************:*.**:***:***:***::************::*************************************:**:***********************************************************************.************************************::******:******.***::.*:.****:****************** **********.**:: ****:****..:** :*::.****.***: ..*:*** :::**** ::*: ** * ::***** : .. : :* * . : .: . * ** .* : ..::*:. . **********:* :*:**::******** **:*:*******:***************:****** ****:*****. **:*:*:**:::** ****:***:*:::*:*:*::*.:**:*:**** .* **: :. * ** *****.:*** **: ***** : : *:***.*: . ***** .*: *:*:**************************:******************.:*****::: *****:*:.***** ****************************:*******:**:******:::******:* **. ..:.: . .: * :. * .: .* : . ::*: .::** ***. **:***:*:* : :: *** : : : :** .:: :* * .:* ****** *::. :: .. * :. *****.* *. ...:. . *::. :*. : . . ** ** :. :* : :: : ::** .* * ***..*: .:. .: : ::**:** *: * * **: . :.* * * *:**::**: **: * **:.::**:***::* ***.**:**:****::*:* *** *. *****", "identical_positions": 828, "similar_positions": 323, "identity": "55.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-214", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O76090-1", "uniprot_id": "BEST1_HUMAN", "id": "O76090-1", "name": "Bestrophin-1", "aln": "MTITYTSQVANARLGSFSRLLLCWRGSIYKLLYGEFLIFLLCYYIIRFIYRLALTEEQQLMFEKLTLYCDSYIQLIPISFVLGFYVTLVVTRWWNQYENLPWPDRLMSLVSGFVEGKDEQGRLLRRTLIRYANLGNVLILRSVSTAVYKRFPSAQHLVQAGFMTPAEHKQLEKLSLPHNMFWVPWVWFANLSMKAWLGGRIRDPILLQSLLNEMNTLRTQCGHLYAYDWISIPLVYTQVVTVAVYSFFLTCLVGRQFLNPAKAYPGHELDLVVPVFTFLQFFFYVGWLKVAEQLINPFGEDDDDFETNWIVDRNLQVSLLAVDEMHQDLPRMEPDMYWNKPEPQPPYTAASAQFRRASFMGSTFNISLNKEEMEFQPN----QEDEED----AHAGIIGRFLGLQSHDHHPPRANSRTKLLWPKRESLLHEGLPKNHKAAKQNVRGQEDNKAWKLKAVDAFKSAPLYQRPGYYSAPQTPLSPTPMFFPLEPS------APSKLHSVTGIDTKDKSLKTVSSGAKKSFELLSESDGALMEH----PEVSQVRRKTVEFNLTD---------MPEIPENHLKEP-LEQSP---------------------------------------TNIHTTLKDHMDPYWALENRDEAHS------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88870-1", "uniprot_id": "BEST1_MOUSE", "id": "O88870-1", "name": "Bestrophin-1", "aln": "MTITYTNKVANARLGSFSSLLLCWRGSIYKLLYGEFLVFIFLYYSIRGLYRMVLSSDQQLLFEKLALYCDSYIQLIPISFVLGFYVTLVVSRWWSQYENLPWPDRLMIQVSSFVEGKDEEGRLLRRTLIRYAILGQVLILRSISTSVYKRFPTLHHLVLAGFMTHGEHKQLQKLGLPHNTFWVPWVWFANLSMKAYLGGRIRDTVLLQSLMNEVCTLRTQCGQLYAYDWISIPLVYTQVVTVAVYSFFLACLIGRQFLNPNKDYPGHEMDLVVPVFTILQFLFYMGWLKVAEQLINPFGEDDDDFETNWIIDRNLQVSLLSVDGMHQNLPPMERDMYWNEAAPQPPYTAASARSRRHSFMGSTFNISLKKEDLELWSK----EEADTDKKESGYSSTIGCFLGLQPKNYHLPLKDLKTKLLCSK-NPLLEG----QCKDANQ--KNQKD--VWKFKGLDFLKCVPRFKRRGSHCGPQAPSS-----HPTEQS------APS------------------SS---------DTGDGPSTDY----QEICHMKKKTVEFNLN----------IPESPTEHLQQRRLDQMS---------------------------------------TNIQALMKEHAESYPYRDEAGTKPVLYE---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2R8Q9T0-1", "uniprot_id": "A0A2R8Q9T0_DANRE", "id": "A0A2R8Q9T0-1", "name": "Bestrophin homolog", "aln": "MTVTYSRRVADARLGTFYRLLLRWKGSIYKLLYRELLIFTVMYCIISITYRCVLTEEQRRMFEKLSLYCDQYAQLIPVSFVLGFYVTLVVSRWWGQFESVPWPDRLSALVSGHVRGADEGARLIRRSLMRYANLSGILIYRSVSTAVYKRFPTMSHLVQAGLMTAEELRQLQELPSPHNKFWVPCMWFVSLAMRARSEGRINNDVAMTAILNELNTLRSQCMRLYGYDWISLPLVYTQVVTVAVYSFFLTCLIGRQFLDPAQGYPGHNLDFYLPVFTLLQFFFYVGWLKVAEQLINPFGEDDDDFETNWLVDRNLQVSLLSVDEMYDLVPLVERDKYWDEAEPQPPYTAASAEHRKPSFMGSALDISVPKEEMEFQHNLEQIKEHEEANHSTPFLGSLSRLLGVQSPNFPRSTPTSRVSLLRRRPRAPFSRFPLYLHSESSQMPSHSRN----TDVSEDAFSAMPLYERPGFYSCPQTPIHCIPPPVPRPRPRRAHGDSSSSLTQPMVGSQILALPDTPAPPSSAFPWVGEDSEHPAFSFPDPVPEICPLTKARLIQGLPSRRPLPLRLSVDKSPSPSTPERVFSFTPPSWPQTQINTASSVNVNVTNSNNNLCNGTANNPWPISRSSNASTANPVSTSPTATQHSANQQNSPNDSGISLADGDLLGAAVKTREQL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:**: :**:****:* *** *:******** *:*:* . * * ** .*:.:*: :****:****.* ****:************:***.*:*.:****** **..*.* ** .**:**:*:*** *. :** **:**:******: *** **:** * :**::* *** **** :**..*:*:* ***.: : : :::**: ***:** :**.*****:*****************:**:*****:* : ****::*: :****:***:**:************************::*********:** *:: :* :* * **::. **********. *: *****:::**: **::*: : :* : . . :. :**:*. :. . :..** : .. : . :.* ..: . . * :.. * ::* * :. **:* * . :.* :. . .: . .. *:. : : : .* : : * : :. . :* : .. .. . ", "identical_positions": 256, "similar_positions": 152, "identity": "37.87%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-22", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P56381-1", "uniprot_id": "ATP5E_HUMAN", "id": "P56381-1", "name": "ATP synthase F(1) complex subunit epsilon, mitochondrial", "aln": "MVAYWRQAGLSYIRYSQICAKAVRDALKTEFKANAEKTSGSNVKIVKV-KKE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56382-1", "uniprot_id": "ATP5E_MOUSE", "id": "P56382-1", "name": "ATP synthase F(1) complex subunit epsilon, mitochondrial", "aln": "MVAYWRQAGLSYIRFSQICAKAVRDALKTEFKANAEKTSGSSIKIVKVSKKE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F8W3H2-1", "uniprot_id": "F8W3H2_DANRE", "id": "F8W3H2-1", "name": "", "aln": "MVAYWRQAGLSYIRYSAICARVVRAALKPQIKAEAIKNAESNVRVIKA-KTT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**************:* ***:.** ***.::**:* *.: *.::::*. *. ", "identical_positions": 30, "similar_positions": 16, "identity": "57.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-222", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q04519-1", "uniprot_id": "ASM_MOUSE", "id": "Q04519-1", "name": "Sphingomyelin phosphodiesterase", "aln": "MPHHRASSGQDHLRAGWEQRLERSLPAPRVGLLWMG------LGLALVLALFDSTVLWVPARAYPLPSEGHSVKFSAIAPPLQSAFGWQNLTCPACKVLFTALNHGLKKEPNVARVGSVAIKICKMLNIAPLDVCQSAVHLFEDDVVEVWTRSVLSPSEACGLLLGSSCGHWDIFSTWNISLPSVPKPPPKPPSPPAPGAPVSRVLFLTDLHWDHEYLEGTDPYCADP----LCCRRGSGWPPNSQKGAGFWGEYSKCDLPLRTLESLLKG-LGPAGPFEMVYWTGDIP-------AHDVWQQSRQDQLRALTTITDLVRKFLG-PVPVYPAVGNHESTPVNG--FPPPFIKGNQSSQWLYEAMAKAWEPWLPADALHTLRIGGFYALTPRPGLRLISLNMNFCSRENFWLLINSTDPAGQLQWLVEELQAAENRGDKVHIIGHIPPG---HCLKSWSWNYYKIIARYENTLAGQFFGHTHVDEFEIFYDEETLSRPLAVA---FLAPSATTFINLNPGYRVYQIDG------------------NYPGSSHVVLDHETYILNLTQAN-----AAGGTPSWKRLYRARETYGLPDAMPASWHN---LVYRMRDDEQLFQTFWFLYHKGHPPSEPCGTPCRLATLCAQLSAR-----ADSPALCRHLMPNGSLPDANRLWSRPLLC----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F7ETC0-1", "uniprot_id": "F7ETC0_RAT", "id": "F7ETC0-1", "name": "Sphingomyelin phosphodiesterase", "aln": "MPHHGASSGQGHLRAGWEQRLERSLPAPKLGLLWMG------LGLALVLALFDSTVLWVPARAYPLPSQGHSVKFSAVAPQLQNAFGWRNLTCPACKVLFTALNYGLK-EPNVARVGSVAIKMCKMLNIAPLNVCQSAVHLFEDDVVDVWTRSVLSPSEACGLLLGSSCGHWDIFSTWNISLPSVPKPPPKPPSPPAPGAPVSRVLFLTDLHWDHDYLEGTDPNCADP----LCCRRGSGWPPNSRTGAGYWGEYSKCDLPLRTLESLLKG-LGPAGPFEMVYWTGDIP-------AHDVWQQSRQDQLRALNTITDLVWKFLG-PVPVYPAVGNHESTPVNG--FPPPFIKGNQSSQWLYEAMAKAWEPWLPADALHTLRIGGFYALTPRPGLRLISLNMNFCSRENFWLLINSTDPAGQLQWLVDELQAAENRGDKVHIIGHIPPG---HCLKSWSWNYYKIIARYENTLAGQFFGHTHVDEFEIFYDEETLSRPLAVA---FLGPSATTFINLNPGYRVYQIDG------------------NYPGSSHVVLDHETYILNLTQAN-----APGGTPSWKRLYRARETYGLPDAMPASWHN---LVYRMRADEQLFQTFWFLYHKGHPPSEPCGTPCRLATLCAQLSAR-----ADSPALCRHLMPNGSLPDAHSLWSRPLLC----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P17405-1", "uniprot_id": "ASM_HUMAN", "id": "P17405-1", "name": "Sphingomyelin phosphodiesterase", "aln": "MPRYGASLRQSCPRSGREQGQDGTAGAP--GLLWMGLVLALALALALALALSDSRVLWAPAEAHPLSPQGHPARLHRIVPRLRDVFGWGNLTCPICKGLFTAINLGLKKEPNVARVGSVAIKLCNLLKIAPPAVCQSIVHLFEDDMVEVWRRSVLSPSEACGLLLGSTCGHWDIFSSWNISLPTVPKPPPKPPSPPAPGAPVSRILFLTDLHWDHDYLEGTDPDCADP----LCCRRGSGLPPASRPGAGYWGEYSKCDLPLRTLESLLSG-LGPAGPFDMVYWTGDIP-------AHDVWHQTRQDQLRALTTVTALVRKFLG-PVPVYPAVGNHESTPVNS--FPPPFIEGNHSSRWLYEAMAKAWEPWLPAEALRTLRIGGFYALSPYPGLRLISLNMNFCSRENFWLLINSTDPAGQLQWLVGELQAAEDRGDKVHIIGHIPPG---HCLKSWSWNYYRIVARYENTLAAQFFGHTHVDEFEVFYDEETLSRPLAVA---FLAPSATTYIGLNPGYRVYQIDG------------------NYSGSSHVVLDHETYILNLTQAN-----IPGAIPHWQLLYRARETYGLPNTLPTAWHN---LVYRMRGDMQLFQTFWFLYHKGHPPSEPCGTPCRLATLCAQLSAR-----ADSPALCRHLMPDGSLPEAQSLWPRPLFC----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P933-1", "uniprot_id": "A0A8M1P933_DANRE", "id": "A0A8M1P933-1", "name": "Sphingomyelin phosphodiesterase", "aln": "-----------------MKRPVYELTVFLLWTLFFG-------PLCFSYPLEGG-------------TDVPQLRVVEELDRLKLGFGWRNLSCVLCKAIFASVDIALLSDSNMERVSRALGEVCVRLHLANPDVCRDITALFRADVIRALQESFLWPTEACAVLVGPSCGHFDIYAPWNVSLPQIPKPPVKPPSPPKPGSPRSRILFLTDIHWDAEYTEGSLAECNKP----LCCRNDSGRASWRHAGAGYWGTYSKCDLPLRTVENLLEN-VAKSGPWDWVYWTGDIP-------AHNVWSQTRNQQLNELVTISRLIHKHLGRNVTVYPAVGNHESTPVNS--FPPPFVHGNHSSRWLYETMAKEWAPWLPEEALETIRRGGFYSVEVEPGLRLVSLNMNFCSRENYWLMVNSTDPADQLQWLIQILQESENKGEKVHIIGHIPPG---FCLSSWSWNYYHIVNRYESTITGQFFGHTHTDEFQMFYDEETLTRPLSVA---FIAPSVTTFVNLNPGYRVYYVDG------------------NYPDSSRMVLDHETFILNLTLANNRP-LKPDPRPSWTLLYRASEAYGLSTLFPSDMEA---LIKHMVNDDRIFQQFWYLFHKGH-VSKPCKDTCKTSIICFLHSGR-----YDLLTQCSPLHGDT---------PKKSMC----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04119-1", "uniprot_id": "PPN1_YEAST", "id": "Q04119-1", "name": "Endopolyphosphatase", "aln": "----MVVVGKSEVRNVSMSRPKKKSLIAILSTCVLF----------FLVFIIGAKFQYVSVFSKFLDDRGDNESLQLLNDIEFTRLGLTPREPVIIKDVKTGKERKLH--GRFLHITDIHPDPYYVEGSSIDAVCHTGKPSKKKDVAPKFGKAMSG-CDSPVILMEETLRWIKENLRDKIDFVIWTGDNIRHDNDRKHPRTEAQIFDMNNIVADKMTELFSAGNEEDPRDFDVSVIPSLGNNDVFPHNMFALGPTLQTREYYRIWKNFVPQQQQRTFDRSASFLTEVIPGKLAVLSINTLYLFKANPLVDNCNSKKEPGYQLLLWFGYVLEELRSRGMKVWLSGHVPPIAKNFDQSCYDKFTLWTHEYRDIIIGGLYGHMNIDHFIPTDGKKARKSLLKAMEQSTRVQQGEDSNEEDEETELNRILDHAMAAK----EVFLMGAKPSNKEAYMNTVRDTYYRKVWNKLERVDEKNVENEKKKKEKKDKKKKKPITRKELIERYSIVNIGGSVIPTFNPSFRIWEYNITDIVNDSNFAVSEYKPWDEFFESLNKIMEDSLLEDEMDSSNIEVGINREKMGEKKNKKKKKNDKTMPIEMPDKYELGPAYVPQLFTPTRFVQFYADLEKINQELHNSFVESKDIFRYEIEYTSDEKPYSMDSLTVGSYLDLAGRLYENKPAWEKYVEWSFASSGYKDD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : : .. . :* * : :. : * .. :: . : **: . *: .:. :: :*: : . ::.: . : . . :::: :.:: * : .* :. . * . * : * :.:: : . : * ** : :: . : : : . : * * : .: . . .** . ::*. : :: : : :. . * . . : : *: .:* : *. * :*: :: :: :*.::* *.. . . . * :: : * . :. ...: .* : .::.::* : :: . :. :**.:*:: : :: * . :::.. :: :* : : :. :* . : :: ::.* : * : .: :. . :. * : * : ", "identical_positions": 43, "similar_positions": 175, "identity": "6.19%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-223", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZCG1-1", "uniprot_id": "D3ZCG1_RAT", "id": "D3ZCG1-1", "name": "", "aln": "MELGRPGAAATAFRQRWPAWMLLWVSTLSCSFSLPASLPPSLVPRVRSSYTLGKTFLGLDKCNACIGTSICKKFFKEEIRLDNSLVSHLGLPSQDLLSYAANYSDDSKTWRPVEISRLVSKYQSEISDKRICASASGPKTCSIERILRKTGRFQKWLQAKRLTPDLVQGLPSPFLHCPSQRLLDRVVRRYAEVVDAGSIFMDHFTDRDKLRLLYTLAVNAHPIILQIFPGAEGWPMPKYLGSCGR-FLVSTSTRPLQEFYDAPPEQAADIAYQLLGVLESLRSNDLNYFFYFTHVDAGMFGIFDN-GHLFIRDASALGIIDKQEASQ-AADRTGENEDIFSCLVSGCQVQMSSCDTVPEKQNLVLVCQQLLPQLLRG-KFPSPVQQEIDSALSLCSKDASTNLEVFGATSLLKNILRSLRTCDPRFAYRYPDCKYNDRF-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C3I9-1", "uniprot_id": "DIK2B_MOUSE", "id": "Q8C3I9-1", "name": "Divergent protein kinase domain 2B", "aln": "MESQWRGAAATAFHQHWLARLLLWVSTLSCSFSLPASLPPSLVPRVRSSYTMGKTFLGLDKCNACIGTSICKKFFKEEIRFDNSLASHLGLPPQDLHSYAANYSDDSKTWRPVEISQLVSRYQIEISDRRICASVSAPKTCSIERILQKTGRFQKWLQAKRLTPDLVQGLPSPFLRCPSQRLLDRVVRRYAEVVDAGSIFMDHFTAGDKLRLLYTLAVNAHPIILQIFPGAEGWPMPRYLGSCGR-FLVSTSTRPLQEFYDASPEQAADLAYQLLRVLESLRSNDLNYFFYFTHVDAGMFGIFDN-GHLFIRDASALGIIDKQEGSQ-AAARTGENEDIFSCLVSDCQIQLSSCDTVPEKQSLVLVCQQLLPQLLQG-KFPSPVQKEIDSALSLCSKDNSTDLEVLGATSWLKDILRSLRTCDPRFAYRYPDCKYNDRF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H7Y0-1", "uniprot_id": "DIK2B_HUMAN", "id": "Q9H7Y0-1", "name": "Divergent protein kinase domain 2B", "aln": "MEP-QLGPEAAALRPGWLA-LLLWVSALSCSFSLPASSLSSLVPQVRTSYNFGRTFLGLDKCNACIGTSICKKFFKEEIRSDNWLASHLGLPPDSLLSYPANYSDDSKIWRPVEIFRLVSKYQNEISDRRICASASAPKTCSIERVLRKTERFQKWLQAKRLTPDLVQGLASPLLRCPSQRLLDRVVRRYAEVADAGSIFMDHFTDRDKLRLLYTLAVNSHPILLQIFPGAEGWPLPKYLGSCGR-FLVSTSTRPLQEFYDAPPDQAADLAYQLLGVLESLRSNDLNYFFYFTHIDAGMFGVFNN-GHLFIRDASAVGVIDKQEGSQ-EANRAGENKDIFSCLVSGCQAQLPSCESISEKQSLVLVCQKLLPRLLQG-RFPSPVQDDIDSILVQCGDSIRPDPEVLGAASQLKDILRPLRTCDSRFAYRYPDCKYNDKF-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TFN4-1", "uniprot_id": "A0A8N7TFN4_DANRE", "id": "A0A8N7TFN4-1", "name": "", "aln": "------------MAGIWSG---VWILCFILVFGTAD---PSPAPQDK-SHDFRKIFLGLDKCNACIGTSICKKFFKDEIRFERRLTAQSNLSSADVRSYEGNYTDSTAGWRPVVVSRLMSPHLHQLSDNSICTSAGKGKSCSIEGVLRATSRFQTWVHSNLLLPSMVKGLVTPMLRCPSQRLLDRIVRRYFEVTDVGSVQMKHFNEKDKLRLLYTLAVNQQPLILQMFPGTEGWPFLRYHGSCGR-LMVWAASRALRTLFSSPLERRADLAYQLLHITQSLSANSLRFRLFYTRIPEDMFGILED-NKVFIVDTSTIGIIDLQEGHPPDKDLLPEELDVFSCLSGSC-VRPPPCETVREAQSFILLCKYILNNLLTSNDKQSGLPRAAVDELLVCADPSQLDQTIIKSVQSLKNILKTLRPCSPQYAYRYPECLYSDKF-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W280-1", "uniprot_id": "Q9W280_DROME", "id": "Q9W280-1", "name": "FAM69 protein-kinase domain-containing protein", "aln": "------------------------------------------MHLSHGQLKVVLILALLQELQVKPQREVFQELFEKDLRLCPDCFVGQSEPCGEIFQKIAEPSD---------WSRLVKAISLLVDRRAIYFLRLKDRDQEVQLVAKR-----KIIDAQSNQIKNVKKDFYELEERPGGFHLCRTLAR-----EPRFVSYLEQRGHAAASVWFYMMYYVSPLLMQELH-LQGFPVPTTYASCGLTHFQSNAGRTLAHYVDAEEGLRVELALQLIQLSLKLTFGFADFRIILTDFTADNLAYDEDTKKVYLIDLDSVVLVDASFAAGHAEKYEPLTGEGFTFDVSAF------CSGHQLDANIYQACLLLRDYLLKN--LDNEKLQLLLEQCVACQDD----------------------FCDMRFQHAYDLIKVLESNN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : *:: :. .: :::*:.::* . . .: . .: :* :*:. :. . * : .:: : : . :.:: . *: : . *. * * : * : : . : : : *:::* : :*:*. .*** : : *.* .: .::* **: : .* . : : * . . :. :: :::: * .:: ::* . . : *: . *. .: * : ** . . . * . *. :: : * : ", "identical_positions": 35, "similar_positions": 109, "identity": "7.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-225", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9GQF1-1", "uniprot_id": "JIP3_DROME", "id": "Q9GQF1-1", "name": "JNK-interacting protein 3", "aln": "MMDNDDALLNNGGPQSGAETVYGTEDNNMVMSEKNEQVVSIVQQLAGSIYQEFERMINRYDEDVVKNLMPLLVNVLECLDASYRINQEQDVEVELLREDNEQLVTQYEREKSARKQSEQKLLEAEDLAEQENKELATRLESVESIVRMLELKHKNSLEHASRLEEREADLKKEYNKLHERYTELFKNHVDYMERTKMLMGSTHSQMSTASERMDVSRARLNPVARSS--------GPVSYGFASLENSVMLDTETICSVGSQSDDSGPPSLQNELDNLSGTLERG-------AATDALQQQHHATSPQSPDSSPVVPNVPTNVGRSTTKKEQRSDNNLYQELSFQDNEESEENEIVTGSWVHPGEYASSANDNYFGMGKEVENLIMENNELLATKNALNIVKDDLIVKVDELTGEVEIVREELNAMQQSRTKLRQRISELEDELKKAKEQVKQQNTEQEENDVPLAQRKRFTRVEMAMVLMERNQYKERLMELQEAVRLTEILRASRTVDNLDRKSKQSIWKYFSNLFTPSNRPTERVADGLGGGPMFRHTGGGSPAHSHGSPSRGSGGGDNRLALTSGQPPVHPASAGLANALIMPKDYAEEGSSERISARRREQYRQLRAHVQKEDGRLHAYGWSLP--INKASQEANPNRHSGGVPVPVYCNPLAEASPHMKVFCAAGVNLHGGFTKNGQSLIPANSPYAPKSTLKIAEITSPTADQSMEALDRQMARVSLETLEPETQLSSFVWICTSTHAASTVSVVDANQSATVLDAFPICAS-HLLCIASVQGAMESDYALLEQSEVVKAGEMLQRPGEGTELLGKVEFVRVKPKSDDEQNSNEKQQQEEEEAKEATEKSNEQLPAVSAEEPLGNVEAIKIRQPLPGAPQRLSTDGNQTNNNNNSSSSSNLLFATKSLNPILETKDRDEPAMSSVGPTMWLGAQDGWLYVHSSVGRWHECLHRVLLPDAVLAIVHVEARVVVALANAQLAVFRRQTDGQWDLNSYHLVTLGDR-NHSIRCLCVAGERIWAAHRNKIFIVDPVSLNIVHSLDAHPRKESQVRQMAATGAGVWVSIRLDSTLRLYNTHTFEHKQDVDIEPYVSKMLGTGKLGFSFVRITALMVSCNRLWIGTSNGVIISVPLAEVQPKSSSDPHGQMPLCCMANAQLSFHGHRDAVKFFVSVPMLQQPNLNGGLTFTNKRPDMLVMCGGEGYIDFRINDNDMENSIQLEPNQTIENRGDKSYLIVWHVSQR-------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M3AHZ5-1", "uniprot_id": "A0A8M3AHZ5_DANRE", "id": "A0A8M3AHZ5-1", "name": "", "aln": "-MDCGESFCGSG---------------------ELELDPDIVSEEAGKLYSELQSVVETHGADVVESLLPILVWVLEGLASCRAQLREREETSEKEKGEREELLDRYQSEKTLRRQSQERYLELDDQFEQERRAMRSRENEREKRERELEKKAREQADQLMALEEQKSNLSRELNSLKHTHNKLVLTHRDLLEKKKEWESEASAFRNHVHSKYSEAVSNQGQTDTSSSEEHCPEAGSVNDSTSTTITNDNKVTDAEVNHNNESFISEIISSTPELAHLKKCVETSTPVCLKTMTSEINSSLFDEIKQDPEDKNEEDGDQKLKVGEKTNVETMENDSDCLEYQLRNTDSVFSELSELSRDYVENVDKGASVRD----SSDQFEQILSQYEELKCSHEMVDTARKALISRVEELTNERSALNLELVSCRETITRFEGKIKEMEEESKRLQKELEMFQSENPDASTPTSLR-RFSRSEMARVVMEKNQYKERLFELQEAVRRSQTLKVTKEEHPP-VEGKGSVWSRFNRFLG---------------------------------LTKGQLGPATALAVTMSSTPAPAQAPAGSPKHLSTKPPQTENSSS-PRLRKRELYREIRSHVWGTLGKKQLHGWSMPLAITNIKQNFEPLPEPKDVPILIQLRLLDQRDATAKLTCAVAVPP-----------------------------------------------------EISGEQTCSVWAVTGPASSSDVTVIDPARSNTILDQFSLPPTSPALCICAVP-----------------------------------------------------------------------------------------------------------------------------------------PTGNTLG-TVWIGTQDGGVLIHSSSSSRRHCLQSVNLSEGVHSLTYSQDEVVAGLADGTLVFFS-HNSGMWDLQSHEVLSLDTPPLQPIRCCLAKEGCLWVGYWNKVYMISAKQRKIQKSFSVSERNEQQVRFLCAAGSGVWASCRLDSILRLFDWTTGRPLQEVDLSSMVTKALGSAFLSLSPLQITAMSVVSGRLWVGTGSGAIFSIPLSLTSESCS------IPYCSLASAQLCYHGHRQAVKFIISAPGCYSASNSADGAATS---SQLILSGGEGYINFRIGDDGSD-----GASEYVLQRSERSHMIIWQSPILCVPSPAL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** .::: ..* : * .**.: **.:*.*:: ::: :. ***:.*:*:** *** * :. :*:: * : :.*:*: :*: **: *:**::: ** :* ***.: : :* :. *. * ** * ::. :: ***::::*.:* *.*:. :.:*. .* * :*:.* ..: : . . .: . : :. . . ** *.*. . :: .. *:: . ..:* * * ** :*. :* . ::: .. .. . :. *.. : :**..*. : ..*.: : : :. .* . :: .:*. : .:*..* ..:.*::: : :** .::: :: .:. ** :*:***.* . :. ** : ::: *::. :*.*:*:* *: ::::: ::*: : ..* : * **:* *** *:**:*******:******* :: *:.:: . :.* *:*. *..:: ::*. * . **:* ...*. . :.. : : .* *.**. *:** **::*:** *: : :***:* *.: .*: :* .. .**: : . * : .. *: **..* * . : :. ** *.. ::* *:*:*. :* *:** *.: .: ***.:* *: .::* *:*:*:*** : :*** . :.**: * *.:.* ::.: : .**..**:. *..* :..* ***:*:.:::*. :.*** . :*..: **::::.. . :* :*:.. *:*.*** :.*:*:***.* **** ***:: * . *:**:.. *:* **:. *.:* ::***: * ..***:**..*.*:*:**: .. ..* :* *.:*.***.:****:****::*.* ... ... : *. . *::.******:***.*:. : ..: : :*.::*::*:*: . ", "identical_positions": 286, "similar_positions": 401, "identity": "22.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-227", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5M877-1", "uniprot_id": "SPSB2_RAT", "id": "Q5M877-1", "name": "SPRY domain-containing SOCS box protein 2", "aln": "-----------------------------MGQT-------ALARGSSSTPSSHALYSDLSPPEGLEELLSAPPPDLGAQRHHGWNPKDCSENIDVKEGGLCFERRPVAQSTDGVRGKRGYSRGLHAWEISWPLEQRGTHAVVGVATALAPLQADHYAALLGSNSESWGWDIGRGKLYHQSKGLEAPQYPAGPQGEQLVVPERLLVVLDMEEGTLGYSIGGTYLGPAFRGL-KGRTLYPSVSAVWGQCQVRIRYLGERRAEEPQSLLHLSRLCVRHALGDTRLGQISSLPLPPAMKRYLLYK-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9P584-1", "uniprot_id": "A0A8M9P584_DANRE", "id": "A0A8M9P584-1", "name": "", "aln": "MRDQQTDGADSARALTEVDHLVRFLRSDWMGLTLCCWLRDGLPKNPNQSSSAFTPFS-VTPPIRLAVLLDTPPVAPGNPRSQ-WSPTHLSPNLQRCVSGVRVHRGHVEQSSDAARAAVGTSTGLHIWEVKWEGQQRGSHALLGVSTHKSPLQASGYKALIGGDSCSWGWELSTNQLWHDGK--EGRSYPGGGATGVLSVPDCVLLVVDADAGTLGYVVDDCYLGVAFQDLPKGVELFPAVSCVWGGAEICIRYLSGTTRDAP-ALQALSRLSARRALRLHGT-QNHTHSLPSALQRLLLDTHTHHRDTPEHAQTQMLLVT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** * .*.:....:.*:.: :* ::** * **.:** * * : *.*.. * *:: .*: ..* * **:*..*. * * *** **:.* :***:**::**:* :****. * **:*.:* ****::. .:*:*:.* *. .**.* * **: :*:*:* : ***** :.. *** **:.* ** *:*:**.*** .:: ****. : * :* ****..*:** * : .**.*::* ** . ", "identical_positions": 108, "similar_positions": 82, "identity": "33.75%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-228", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2N2-1", "uniprot_id": "D4A2N2_RAT", "id": "D4A2N2-1", "name": "Type II inositol 1,4,5-trisphosphate 5-phosphatase", "aln": "MDQSVAIQETLVEGEYCVIAVQGVLCKGDSRQSRLLGLVRYRLENDVQEHALFLYTHRRMAITGDDVALDQIVPLSKDFMLEEVSPDGELYILGSDVTVQLTTAELRLVFQLPFGSHTRTFLQEVARACPGFDPETR--DPEFLWLCRHRCAESEAESPKPREWNSDPGTRSGFAPIGGGRYQSWNARRGLEDVLPRGPGYILLWGGATKEPEFLLAEEVHEGGPVRGPRARGGRRDEALEEADWEMSAGGGSRERDCAGGYNVDSSRPNGRGLLPLDQSSGARCPDKPENSLTRQNRSKAEIT-DMVRSSTITVSDKAHILSMQKFGLRDTMVRSHLLQKEGEYTYIQNFRFFVGTYNVNGQSPKEC---LRPWLSSDTKAPDVYCVGFQELDLSKEAFFFHDTPK--EEEWFKAVSESLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQLHNTSICVVNSHLAAHTEEYERRNQDYRDICSRMQFSQVDPSLPPLTISKHDVILWLGDLNYRIEELD-VEKVKKLVEEKAFHTLYAHDQLKIQVAAKTVFEGFTEGEITFQPTYKYDTGSDNWDTSEKCRAPAWCDRVLWRGKNISQLSYQSHMSLKTSDHKPVSSVFEIGVRVVNEELYRKTLEEIVRSLDKMENANIPSVTLSKREFCFENVKYMQLQTATFTIHN-GQVPCEFEFINKPDEETYCKQWLTAKPSRGFLLPDSHVEIELELFVNKATATKLNSGK--DTIEDILVLHLHRGKDYFLSVTGNYLPSCFGSPIHTLCYMREPILDLPLKIVNELTLMTVQTADDRSQLEKPMEIPKELWMMVDYLYRNAVQQEDLFQ----QPGLRPEFEHIRDCLDTGMIDHLCANNHSVAEALLLFLESLPEPVICYSAYHSCLECSGSHTASKQVISTLPTFHKNVFSYLMAFLQELLKNSAKNHLDENILASIFGSLLLRSPAGHRKLDMAEKKKAQEFIHHFLCNPL--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K337-1", "uniprot_id": "I5P2_MOUSE", "id": "Q8K337-1", "name": "Type II inositol 1,4,5-trisphosphate 5-phosphatase", "aln": "MDQSVAIQETLVEGEYCVIAVQGVLCKGDSRQSRLLGLVRYRLENDAQEHALFLYTHRRMAITGDDVSLDQIVPLSKDFMLEEVSPDGELYILGSDVTVQLNTAELKLVFQLPFGSHTRTFLQEVARACPGFDPETR--DPEFEWLSRHTCAEPDAESPKPREWNSDPGTRSGFAPIGGSRHQSRNARRGLEDVLPRGPGYILLWGGAAEEPEFLLAEEMHEGGPVRGRRPLAGRRDEALEEADWEMSAGGGSRERDCAGVSNVDSSRPNGRGP---DQPSGARCPEKPENSLTRQNKSKSDMS-EKVRSATVTVSDKAHILSVQKFGLRDTIVRSHLVQKEENYTYIQNFRFFVGTYNVNGQSPKEC---LRPWLSHSALAPDVYCVGFQELDLSKEAFFFHDTPK--EEEWFKAVSESLHPDAKYAKVKFVRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQLHNTSICVVNSHLAAHTEEYERRNQDYRDICSRMQFPQVDPSQPPLTINKHDVILWLGDLNYRIEELD-VGKVKKLVEEKAFQTLYAHDQLKIQVAARTIFDGFTEGEITFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGVRVVNEELYRKTLEEIVRSLDKMENANIPSVTLSKREFCFENVKYMQLQTESFTIHN-SQVPCQFEFINKPDEESYCKQWLTARPSKGFLLPDSHVEIELELFVNKSTATKLNSGK--DTIEDILVLHLERGKDYFLSVSGNYLPSCFGSPIHTLCYMREPILDLPLKTVSDLTLMSVQTADDRSQLENPMEIPKELWMMVDYLYRNAVQQEDLFQ----QPGLRPEFDHIRDCLDTGMIDQLCANNHSVAEALLLFLESLPEPVICYSAYHSCLECSGNYAASKQIILTLPSFHKNVFNYLMAFLQELLKNSANNHLDENILASIFGSLLLRNPARHQKLDMAEKKKAQEFIHQFLCGPL--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32019-1", "uniprot_id": "I5P2_HUMAN", "id": "P32019-1", "name": "Type II inositol 1,4,5-trisphosphate 5-phosphatase", "aln": "MDQSVAIQETLAEGEYCVIAVQGVLCEGDSRQSRLLGLVRYRLEHGGQEHALFLYTHRRMAITGDDVSLDQIVPVSRDFTLEEVSPDGELYILGSDVTVQLDTAELSLVFQLPFGSQTRMFLHEVARACPGFDSATR--DPEFLWLSRYRCAELELEMPTPRGCNSALVTWPGYATIGGGRYPSRKKRWGLEEARPQGAGSVLFWGGAMEKTGFRLMERAHGGGFVWGRSARDGRRDEELEEAGREMSAAAGSRERNTAGGSNFDGLRPNGKGVP-MDQSS--RGQDKPESLQPRQNKSKSEIT-DMVRSSTITVSDKAHILSMQKFGLRDTIVKSHLLQKEEDYTYIQNFRFFAGTYNVNGQSPKEC---LRLWLSNGIQAPDVYCVGFQELDLSKEAFFFHDTPK--EEEWFKAVSEGLHPDAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQFHNTSICVVNSHLAAHIEEYERRNQDYKDICSRMQFCQPDPSLPPLTISNHDVILWLGDLNYRIEELD-VEKVKKLIEEKDFQMLYAYDQLKIQVAAKTVFEGFTEGELTFQPTYKYDTGSDDWDTSEKCRAPAWCDRILWKGKNITQLSYQSHMALKTSDHKPVSSVFDIGVRVVNDELYRKTLEEIVRSLDKMENANIPSVSLSKREFCFQNVKYMQLKVESFTIHN-GQVPCHFEFINKPDEESYCKQWLNANPSRGFLLPDSDVEIDLELFVNKMTATKLNSGE--DKIEDILVLHLDRGKDYFLSVSGNYLPSCFGSPIHTLCYMREPILDLPLETISELTLMPVWTGDDGSQLDSPMEIPKELWMMVDYLYRNAVQQEDLFQ----QPGLRSEFEHIRDCLDTGMIDNLSASNHSVAEALLLFLESLPEPVICYSTYHNCLECSGNYTASKQVISTLPIFHKNVFHYLMAFLRELLKNSAKNHLDENILASIFGSLLLRNPAGHQKLDMTEKKKAQEFIHQFLCNPL--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQB1-1", "uniprot_id": "A0A8M3AQB1_DANRE", "id": "A0A8M3AQB1-1", "name": "", "aln": "MDQSVAIQETLAEGESCTIAVECVSLLNDVRDSKLIGLVRQ-----NKEHALFIYSHRRMAITGEDVTLGQIIPISYDFSVVEVSSPDELAVVGADTRVRVTFLEEELELKLPFGSHTRLFLSEVNRAWSDVCQQYPKEEPKFDWLTKYRKVSKGARSLR--------------KSIG---------------------------ATTVKMSQMKKAERAHTAN------------------------SSALKKEDESARG-----------------------------DALQSQEKVKGEVKDDLIRNSQPVLSNKAQMLGMPQFGLRDNLIKCELLKNEDAYTYIENYSFFLGTYNVNGQTPKES---LSPWLASTASPPDFYLIGFQELDLSKEAFLFNDTPK--EPEWMLAVYKGLHPDAKYALVKLVRLVGIMLLFYVKAEHAPHISEVEAETVGTGVMGRMGNKGAVSIRFQFHNSDICVVNSHLAAHTEEFERRNQDFKDICRRIQFRQEDPTLPPLTILKHNIVLWLGDLNYRISDLE-VDHVKDLISKKDFETLHTYDQLKRQMDEEVVFVGFTEGEIDFQPTYKYDTGSDQWDTSEKCRVPAWCDRILWRGKSIKQLHYQSHMTLKTSDHKPVSSLLEIGIKVVNEESYKRTFEEIVRQIDRLENDCIPSVSLSEREFHFQDVKFMQHQARTVTVHNDGQVPCQFEFIQKLDEPAYCKPWLTANPAKGFLAQGASVDIDLEVFVNRHTAPELNAGL--QQLEDILVLHLERGKDYFISITGSYLPSCFGSSLSALCLLREPIQDMPLESIRELSVKSNSPVIDS--ADKPQEIPKEIWMMVDHLFRYAKKQEDLFQ----QPGLRSEFEEIRDCLDTGCLDTLPGSNHSVAEALLLFLDALPEPVIPFSFYQQCLDCCSDSSHCRQIISMLPQCHKNVFNYLTAFLQELLRHSAYNRLDVNVVAPIFAGLLLRSPD---KQDINEKRKVKEFFQHFLVQTSSDRDIHEKSPE---------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O46094-1", "uniprot_id": "O46094_DROME", "id": "O46094-1", "name": "inositol-polyphosphate 5-phosphatase", "aln": "-------MDTLSEAVANGTATAATRTTKDIVKERFK------------EDETIEYIFEAYQIKGPEYSN-------RLLALVSSQSGGTFAIIAFSYLRTPLSSANELIINKVFAIDHNFQLRQDSKSSITTQQFDLS---------------------------------------------------------------------TAEDGPIKYYYYATES-------------------------------------------------------------------HHYEEFVAKVISFKSTMAQHDPETVLNFRWLNDYRQIG----EVKQELKKRESEYIVYKDIIIYCATWNVNNKTCSDSNNPLRAWLACSEKPPDIYAIGLQELDTPTKAMLNSTQVQAIEKQWIDKMMDSVHPDVEYEILMSHRLVATMLTVIVRKQLRQHIIRCRPKSVARGIFNTLGNKGGVAISLQLNEGNICFVNSHLAAHMGYVEERNQDYNAIVEGIRFDDGR------TISDHDHIFWVGDLNYRIQEPPGQQRPGPLSDAQTYELLLQYDQLRQEMRRGKCFEGYTEGEIKFRPTYKYDPGTDNYDSSEKQRAPAYCDRVLWKGTRIEQLAYNSIMEIRQSDHKPVYAVFQVKVKTRDEVKYKRVQEEVLKAVDKRENDNQPQINVEKTVIDFGTVRFNEPSTRDFNVYNNCPLPVDFSFKEK-DIHAICEPWLHVDPRQDSLLIDSARSIRLKMNANVRTIAGLLRKIRASDNFDILILHVENGRDIFITVTGDYQPSCFGLSMETMCRTDRPLSEYSQDQIKQLMNDESP--------EYRVTMPREFFLLIDYLYRQGSKQVGAFPSYDSRLSLGAQFNSVRDWLDTWSDDPFPANAETAAQALLLLLD-LPEHALLEPVVENLLECTNK-SQAMDYISLLSPPKRNVFMHLCMFLRAGIES---QFYDLHQVASTFGRILLRSTERAAWMDYHSR--CIQFMRLFIDTDVEAMGNGNEGAGTGTGSGSGTRAGLQA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** *. *. . * ..:: *. : * .. *.* : : : : . .. . : ::. . * :: *. . . * : :: : : : . ... : .: : : . ::* :: .* :.* * :: :: .*:***.:: .:. * **: .**.* :*:**** ..:*:: : * :*: : ..:***.:* : ***. ** . *: : :* . ..::*. *::. :****.*:* :*::: .**.******** *.****:. * ::* : ** .*: ::*:*******.: : * . : :. * :***: :: * *:****: *:******.*:*::*:*** *.**:***:**:*. * ** *:* * :: ****** ::::: ::. :: *::. **::: :*: ** *.:.:.: : * *:: : .. ..::* :* .*.* :* * : *: ** . * :. * .: .* *:: .* * . * . ***:**:..*:* *::::*.* ***** .: ::* .*: : . . : :* : :*:*:::::*:*:* . :* . * : .* .:*: :** *** * : .. .:.*:****:*: *** .: . .. *:* .. : . : * *. ::*** :* **: :. : * : :*. *. :***.. * .: :*:: *: ", "identical_positions": 213, "similar_positions": 279, "identity": "20.52%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-231", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R054-1", "uniprot_id": "SRPX2_MOUSE", "id": "Q8R054-1", "name": "Sushi repeat-containing protein SRPX2", "aln": "MMTSPLTQRGALSLLLLLMPAVTPTWYAGSGYSPDESYNEVYAEEVPAARARALDYRVPRWCYTLNIQDGEATCYSPRGGNYHSSLGTRCELSCDRGFRLIGRKSVQCLPSRRWSGTAYCRQIRCHTLPFITSGTYTCTNGMLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPILKPPQHGYLTCSSAGDNYGAICEYHCDGGYERQGTPSRVCQSSRQWSGTPPVCTPMKINVNVNSAAGLLDQFYEKQRLLIVSAPDPSNRYYKMQISMLQQSTCGLDLRHVTIIELVGQPPQEVGRIREQQLSAGIIEELRQFQRLTRSYFNMVLIDKQGIDRERYMEPVTPEEIFTFIDDYLLSNEELARRVEQRDLCE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60687-1", "uniprot_id": "SRPX2_HUMAN", "id": "O60687-1", "name": "Sushi repeat-containing protein SRPX2", "aln": "-MASQLTQRGALFLLFFLTPAVTPTWYAGSGYYPDESYNEVYAEEVP--QAPALDYRVPRWCYTLNIQDGEATCYSPKGGNYHSSLGTRCELSCDRGFRLIGRRSVQCLPSRRWSGTAYCRQMRCHALPFITSGTYTCTNGVLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPTLKPPQHGYLTCTSAGDNYGATCEYHCDGGYDRQGTPSRVCQSSRQWSGSPPICAPMKINVNVNSAAGLLDQFYEKQRLLIISAPDPSNRYYKMQISMLQQSTCGLDLRHVTIIELVGQPPQEVGRIREQQLSANIIEELRQFQRLTRSYFNMVLIDKQGIDRDRYMEPVTPEEIFTFIDDYLLSNQELTQRREQRDICE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F8X0-1", "uniprot_id": "E7F8X0_DANRE", "id": "E7F8X0-1", "name": "Sushi repeat-containing protein SRPX2", "aln": "-----MLKCIILFVELFIIYQALGDNTEGSTFTYHDTNEVVHEDEIY--HTPQLDYKHPQWCHRLKLTSGEVSCTSPRGGRHHSTLGTRCMLSCDRGYKRLGRSSVQCMPNRRWSGSALCRRIRCQVLSVIDHGMYSCNRDFVVDSRCDYTCDEGYQIEGDRYRLCQEDGKWSGTEPTCTDYDPPKLKCPLSREKVAEPGKLTVMVSWDRPVAKDTADRAL-RVLRNGPESGSDFPEGTHVIRYKAYDQAGNMATCKFNVHVEVRRCPKLKPPMHGYLTCSSDGNNYGAICEYHCDPGFERTGFVTRVCQLNRSWSDEAAQCVLMDIKTDVRSAGALLDQFYEKRRLLVVSTPDNGNQKYRLQNMMLQKAGCGLDLRHVTVIELLGSPPRAVGRIKEQRLQPEVIEDLRQALHISMAYFTMVLLDDYGVDRERFVNPTNSEELFSYVDEFLLTEEERERLEMNGDFCE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * : ::: . ** : .:: : *: :*: :: ***: *:**: *:: .**.:* **:**.:**:***** ******:: :** ****:*.*****:* **::**:.*..* * *:*....::******:*..**::**** *:* ***:*** **.*.* ****::** ****:*** ***. * ** *:.**:** :: ** .***.**.**** *****.***:* * *:*** *:*:***** **** ******:* *:**** ****** *::* * :**** .*.**. .. *. *.*:.:*.**..********:***::*:** .*: *::* ***:: *********:***:*.**: ****:**:*.. :**:*** ::: :**.***:*. *:**:*:::*...**:*:::*::**:::* : : *:**", "identical_positions": 241, "similar_positions": 139, "identity": "51.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-232", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61476-1", "uniprot_id": "DAF2_MOUSE", "id": "Q61476-1", "name": "Complement decay-accelerating factor transmembrane isoform", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVSSTWGYDPRAGAGDLVITTTAAGAVTIAVLLFQ-TVCGDCG---------------------PPPDIPNARPIL--GRHSKFAEQSKVAYSCNNGFKQVPDKSNIVVCLENGQWS-SHETFCEKSCDTPERLSFASLKKEYFNMNFFPVGTIVEYECRPGFRKQPSLSGKSTCLED-LV------WSPVAQFCKKKSCPNPKDLDNGHINIPTGILFG------------SEINFSCNPG-------------------------------------------------------------------------------------------------------------------------YRLVGITSILCTIIGNTV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DWDDEFPVCTE----IFCPDPPKINNGIMRGESDSYKYSQ-----------------VVIYSCDKGFILFGNSTIYCTVSK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDVGQWSSPPPQC---------------------------------------------------------------------------------------------------------------------------------------------------------------IEESKVPIKKP-----VVNVPSTGIP-----STPQKPTTES-VPNPGDQPTPQKPST---VKVPATQ------HEPDTTT------RTSTDKGE-SNSGGDR-------------------------------YIYGFVAVIAMID-------------------------------------------------------------------------------------------SLIIVKTLWTILSPNRRSDFQGKERKDVSK--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q61475-1", "uniprot_id": "DAF1_MOUSE", "id": "Q61475-1", "name": "Complement decay-accelerating factor, GPI-anchored", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIR---GRAPRTRP---SPPPPLLPLLSLSLLLLSPTVRGDCG---------------------PPPDIPNARPIL--GRHSKFAEQSKVAYSCNNGFKQVPDKSNIVVCLENGQWS-SHETFCEKSCVAPERLSFASLKKEYLNMNFFPVGTIVEYECRPGFRKQPPLPGKATCLED-LV------WSPVAQFCKKKSCPNPKDLDNGHINIPTGILFG------------SEINFSCNPG-------------------------------------------------------------------------------------------------------------------------YRLVGVSSTFCSVTGNTV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DWDDEFPVCTE----IHCPEPPKINNGIMRGESDSYTYSQ-----------------VVTYSCDKGFILVGNASIYCTVSK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDVGQWSSPPPRC---------------------------------------------------------------------------------------------------------------------------------------------------------------IEKSKVPTKKP-----TINVPSTGTP-----STPQKPTTES-VPNPGDQPTPQKPST---VKVSATQ------HVPVTKTTVRHPIRTSTDKGE-PNTGGDR-------------------------------YIYGHTCLITLT--------------------------------------------------------------------------------------------VLHVMLSLIGYLT-------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P08174-1", "uniprot_id": "DAF_HUMAN", "id": "P08174-1", "name": "Complement decay-accelerating factor", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCG---------------------LPPDVPNAQPAL--EGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWS-DIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQN-LK------WSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFG------------ATISFSCNTG-------------------------------------------------------------------------------------------------------------------------YKLFGSTSSFCLISGSSV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QWSDPLPECRE----IYCPAPPQIDNGIIQGERDHYGYRQ-----------------SVTYACNKGFTMIGEHSIYCTVN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NDEGEWSGPPPEC---------------------------------------------------------------------------------------------------------------------------------------------------------------RGKSLTSKVPP-----TVQKPTT----------VNVPTTEV-SPTS--QKTTTKTTT---PNAQATR------STPVSRTT-KHFHETTPNKGSGTTSGTTR-------------------------------LLSGHTCFTLTG---------------------------------------------------------------------------------------------LLGTLVTMGLLT-------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P04003-1", "uniprot_id": "C4BPA_HUMAN", "id": "P04003-1", "name": "C4b-binding protein alpha chain", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHPPKTPSGALHRKRKMAAWPFSRLWKVSDPILFQMTLIAALLPAVLGNCG---------------------PPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHS-TQTLTCNSDGEWV-YNTFCIYKRCRHPGELRNGQVEIKTD----LSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVG------WSHPLPQCEIVKCKPPPDIRNGRHSG-EENFYAYG----------FSVTYSCDPR-------------------------------------------------------------------------------------------------------------------------FSLLGHASISCTVENETIG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VWRPSPPTCEK----ITCRKPDVSHGEMVSGFGPIYNYKD-----------------TIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKE----------DVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWTPYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYF--------------------------------------------------------------------------------------------------YGDEISFSCHETSRFSAICQGDGTWSPRTPSCGDIC-------------------------------------------------------------------------------------------------------------------------NFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSYS-----HWSAPAPQCK-----ALCRKPELVN-GRLSVDKDQYVEPEN---VTIQCDSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCEQ-------------------------------VLTGKRLMQCLPN-----------------------------------------------------------------------------------------PEDVKMALEVYKLSLEIEQLELQRDSARQSTLDKEL----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q63514-1", "uniprot_id": "C4BPA_RAT", "id": "Q63514-1", "name": "C4b-binding protein alpha chain", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLTAALWVAVFGKCG---------------------PPPDLPYALPAS-EMNQTDFESHTTLRYNCRPGYSRASS-SQSLYCKPLGKWQ-INIACVKKSCRNPGDLQNGKVEVKTD----FLFGSQIEFSCSEGYILIGSSTSYCEIQGKGVS------WSDPLPECVIAKCGMPPDISNGKHNGREEEFFTYR----------SSVTYKCDPD-------------------------------------------------------------------------------------------------------------------------FTLLGNASITCTVVNKTVG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VWSPSPPTCER----IICPWPKVLHGTINSGFKHTYKYKD-----------------SVRFVCQKGFVLRGSGVIHCEADGSWSPVP-VCELNSCTDIPDIPNAALITSPRPRKE----------DVYPVGTVLRYICRPGYEPATRQPMTVICQKDLSWSMLRGCKEICCPVPDPKSVRVIQHEKAHPDNDCTYF--------------------------------------------------------------------------------------------------FGDEVSYTCQNDIMLTATCKSDGTWHPRTPSCHQSC-------------------------------------------------------------------------------------------------------------------------DFPPAIAHGRYTKSSSY-YVRTQVTYECEEGYRLVGEATISCWYS-----QWTPAAPQCK-----ALCRKPEIGN-GVLSTNKDQYVETEN---VTIQCDSGFVMLGSQSITCSENGTWYPKVSRCEQEVPKDCEH-------------------------------VFAGKKLMQCLPN-----------------------------------------------------------------------------------------SNDVKMALEVYKLTLEIKQLQLQIDKAKH--VDREL----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P19070-1", "uniprot_id": "CR2_MOUSE", "id": "P19070-1", "name": "Complement receptor type 2", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLTWFLFYFSEISCDPPPEVKNARKPYYSLPIVPGTVLRYTCSPSYRLIGEKAIFCISENQVHATWDKAPPICESVNKTISCSDPIVPGGFMNKGSKAPFRHGDSVTFTCKANFTMKGSKTVWCQANEMWGPTALPVCESDFPLECP---------------------SLPTIHNGHHTG--QHVDQFVAGLSVTYSCEPGYLLTGK--KTIKCLSSGDWDGVIPTCKEAQCEHPGKFPNGQVKEPLS----LQVGTTVYFSCNEGYQLQGQPSSQCVIVEQKAI------WT-KKPVCKEILCPPPPPVRNGSHTGSFSENVPYG----------STVTYTCDPSPEKGVS-------------------------------------------------------------------------------------------------------------------FTLIGEKTINCTTGSQKTG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IWSGPAPYCVLSTSAVLCLQPKIKRGQILSILKDSYSYND-----------------TVAFSCEPGFTLKGNRSIRCNAHGTWEPPVPVCEKGCQAPPKIINGQKEDSYLLN---------------FDPGTSIRYSCDPGYLLVGEDTIHCTPEGKWTPITPQCTVAECKPVGPHLFKRPQNQFIRTAVNSSCDEGFQLSESAY----------------------------------QLCQGTIPWFIEIRLCKEITCPPPPVIHNGTHTWSSSEDVPYGTVVTYMCYPGPEEGVKFKLIGEQTIHCTSDSRGRGSWSSPAPLCKLSLPAVQCTDVHVENGVKLTDNKAPYFYNDSVMFKCDDGYILSGSSQIRCKANNTWDPEKPLCKKEGCEPMRVHGLPDDSHIKLVKRTCQNGYQLTGYTYEKCQNAENGTWFKKIEVCTVILCQPPPKIANGGHTGMMAKHFLYGNEVSYECDEGFYLLGEKSLQCVNDSKGHGSWSGPPPQCLQSSPLTHCPDPEVKHGYKLNKTHSAFSHNDI---VHFVCNQGFIMNGSHLIRCHTNNTWLPGVPTCIRKASLGCQSPSTIPNGNHTGGSIARFPPGMSVMYSCYQGFLMAGEARLICTHEGTWSQPPPFCKEVNCSFPEDTNGIQKGFQPGKTYRFGATVTLECEDGYTLEGSPQSQCQDDSQWNPPLALCKYRRWSTIPLICGISVGSALIILMSVGFCMILKHRESNYYTKTRPKEGALHLETREVYSIDPYNPAS---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9VYR4-1", "uniprot_id": "Q9VYR4_DROME", "id": "Q9VYR4-1", "name": "", "aln": "-----------------------MFCCNIPVDASVATSTSTSISTYPLQRATKRAMTPPNAMALIMLLLLALCAAGNGQICGPPAVPLNAKVRTITVDSQIAEAHYECDAGYELFGPSAVKCDRRTGWDRDLPFCGVNVAYRKPVNQSSYTRSGPASYANDGKPGNKNPDGQECSETQKEPSPWWRVDLLTPQAVHVVRITTRGCCGHQPLQDLEIRVGNSSADLQRNPLCAWYPGTLDEGVVKTFTCARPLVGQYVAIQLVGVEGSLSLCEVETFTNDEFSVDRCLSPKIGVDTVVTTFSKTCYDFHITKGESFDKAQAICKQTGGDLVHDFRGATSSYILSELERRKSELKPQLVWIGAQKEPGITSRTWKWVNGDVVQKPTWGKDQPNNYNGEQNCVVLDGGRNWLWNDVGCNLDYLHFICQHSPLSCG---------------------SPDAQQNTTVMG-----KKFTLGEKIQYTCPKGHSLLGQ--TERECRLDGTWSGSSPTCKYVDCGSLPELKFGSIHMSEER---TSFGVVATYSCHENYTLIGN-ENRTCAMDG---------WSGKQPECLVDWCPDPQPIAGGDVRFNDKRAGS-------------TATYVCEPG-------------------------------------------------------------------------------------------------------------------------YVLVGEAIISCGLG----G-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EWSSKTPSCRF----VDCGAPARPNRGIAILLNGTTTVNS-----------------VVKYECDEDHWLDGQSELYCTREGKWSGEAPVCELVTCETPSVPSGSFVIGYDYN-----------------VHSKIQYNCDPGHIMHGTPVLECLDSGEWSADAPYCEYIDCGTILPIPYGSHKYVTNTTYVGSEVVFSCSQSHKLSGVLKRTCLESAVW---------------------SDASPKCEEIRCPEPKLAAHSLLSVTGNDRMYGRTLIRTSESSQNTAQTYKIGALAKYRCERGYKMVGEALATCTDSGQWSGTIPECVYVECG--------------------------------------------------------------APEGINNGKVVLATNATYYGAAVLYECNVNFKLNGVSRRLCTEHGNWSHEAPECVEVVCDTPNINENLIVEAGPRAVGSVATFKCAKGRIMMGNDTRVCQKN----GKWTGKSPTCR----PVDCGRPLAIENGRVIVVNDSTLYGGS---AEYHCIPNYNRIGQYLRKCTEDGAWSGKQPRCELATAEGQETSELGTG-------------------------VGIGATVIVALLVIFGLIFLYRNKARPVKNTENVQAAETKDERNAAVMSYSTLEANNRMHMDNNPSATFNTFHGG---------AGGRSNGGGNPDANSNGERLNNNRSENIYDQIPNEQFYDAPYEMRTNDEVYEPEPVASNVITINGISVR-------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M3B6F5-1", "uniprot_id": "A0A8M3B6F5_DANRE", "id": "A0A8M3B6F5-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATVWRNALVLVFVHLVVSQTRFRCGEPPKYPDKQLDIKYIYRPVFNHQDKVSYRCHRGHVPSEGNRMSFCMRGRWTPLTLKCQKVKCNGLADIKNGQYRREGQSYGDKAIVICNQGYVLKGVKFRMCLEKGWSGTDPVCLAPQV---------------------TCSAPTVENRWIKPGERTQYTTQDTVSITCSEGFDLIGS--SVVTCGPNGQWRDLPECHRKVPKMTCPAPAVENRSIKPGERTQYTPQDTVSITCSEGFDLIGSSLVTCGPDGQ---------WQNLPKCHRKVILCSAPAVANGRINAFGNQHKP-R----------DTVSITCSEG-------------------------------------------------------------------------------------------------------------------------FELIGSPQVTCGPDGQWQS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPECHPKRRSAN--VIFCSAPVVANGRIN-AFGNQHKPKD-----------------TVSITCSEGFELIGSSQVTCGPDGQWQGLPECHPKKHLVNVNLCSAPAVANGRINEFG----------NTFKPKDTVSIICSEGFDLIGSPQVTCGPDGQWQSLPECHPKTRLANGKCGPPPSYLHHNVFFREGTPSLTEYSSG-------------------------------------------------------------------------------------------ARIRYKCNLGLRRASGSDIIRCQAGEWTKLALRCQRKSCG--------------------------------------------------------------------------------------------------------------------------SAGEISFGRFQYSGVLFGDSARAICQEGYELIGPEERVCRDG-----GWDGRIPVCEP----VYCPPPPEVKDAEVSDFRNEDVPVGH---MVSYRCQTGALIGTQDLYCTTNGTWSGPAPLCKDISCPRPDIPRGS---------------------------RMRGFRSVYKYGN-------------------------------------------------------------------------------------------TVTIACSPGLRLYGESFVTCGADGNWTPKLPECRR---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7YZX0-1", "uniprot_id": "B7YZX0_DROME", "id": "B7YZX0-1", "name": "", "aln": "MNRLLLQCLVTTILVYKVISVPTSTMSTSIQTTSEIPQQDDDDDDWEEDDDSLESDDDGRVYKNPRNSPSTECPRDEEQATLLGQKCLRKCSSDEDCKSKKKKCLCDGVCGNSCIKPDRECPELAQPSLGQVTVAGRHFGARASYACPHGYHVVGLQSRLCQADGNWAGAEPACKQNIYCLKPPQIEHARNSALPEQETFDLDSTVQYHCHTGYVTNGFPRAKCLAIDNLASWYGPDIQCEPRSCGQPPDPAYGWHAG--ECYTYGCKITYNCGTGYELVGKHERYCQSDGSWTPKELPTCVLVTSVVCPTPENPKNGKATYTTLAYNSVVSYECRYGYTLVGESSSRCGADRKWSGTLPTCKEINCGHPGVLYNGWIENIEAGTGLGASIIFRCQPEMMINGLGSSVCQIDGRWRNALPECLAPCVVPTISQGNVYPIEIITDENGTTIVHPPTTTTQSPTQTQSIGGVEKVKHGTALEVKCDENYEFPVSLLSPPTCN-NGTWS-IIPRCVPARCKSMPRPPKHGMVMAPKT----EHGMKARFKCKDGFKLVSPEGKDVTDPHDYVLTCSFGNWTGETPKCDEVFCSFPGYIPNGKVLLVGNMGLYDYRPYVKKIVNNKQIMYDCDKGYVLEVGPPGATCVGGKWRPLDLPQCLLGQHPRLRWNRRRRRSLQIRQLRSMYLLQRQRQLQRQLIDNQNYIKAIADPVQPSVHRVKRSASPHPNSQPYASDVDRAYSKYYQKIKERYQRYVRKMLGRDRIYQRLHSQDAVGRVGNNLNTHDGGQVTMRGKSNFREFENGNNYLGSGGIGSGGVVGSGVVALPNINQASRNHQVHVNRTPKEELLSNGSPPIASRSLHLNATRSYIEQLKSQIVRRRRRRSSSIGQSPPPSGATIPDAEVDISDGGEAGKGGGGKRLRGPCEELEWDSFANVTTVRPGKVPGRNAVGIMLHLECNAGFKLNIKGENATARCIRGIWKPETPKCLS----APCLVPAVEHGQYYKVEPHTKQLSDKPSLTPLSTYEEIQSNEFITLECEDGFNIQGSAQLRCAHGSWSVNAFSECTSVPCTLPNIPGVIYDGGYRAGLTIGHGSSVSVRCELSTNANPIEMSCHKGILTPPSIPCESGLRKSREELEHATPTPHPKVEHNELDNDHDHHDNGTDEHDDMKMCGPPMLTDGALVYKNADHPELDGAYESGTEIFFNCIPNAAGDRQTWRIICDNGLWIGRSYNCENGTCVFRNNEANVVSFYNDLEIREDVVDFPPGATIISRCMDIGKFSFMGSHERTCIHSEWTNTKPVCSGLNQENDYAMEKAPTILFRHQNGPIAQSNDGKLIVYPG-------TTLHMECLWMRRFGNPKWNVSHTHKNYTEGWVTEADEGRDSTLEYRLSIVDAASDDSGFYSCMTPARHEHTVEVVVRAINCPEIPMRRGLIVNTNDTKLSTRALLSCANGNSLIGASELFCLPS----GNWSAPLPVCES----VECGDIPLGMGSNASSPRVSVLSREVGGRAAFSCASGYGLRGPAEAICNPTGEWSAPLPTCVEVQCDNPGAPQNGYAQG-----SAPYRAGDVVQFNCNPEYMMQGQPIIACQDNARWSGGLPKCVQACSYPGTVISG-------------------------------------------------------RMSSVKFYYAIGESITFTCDAGLDLRGSKVLKCLKNGKWSSAIPTCVTNEGPVGGGGGGGGGGGGGSGSVATNKHLATTMG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .* .. * . * * .: * . : .* *. :.* * * . : *. .. : *. : * . * * . . . * . ", "identical_positions": 16, "similar_positions": 26, "identity": "0.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-237", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7Z4S6-1", "uniprot_id": "KI21A_HUMAN", "id": "Q7Z4S6-1", "name": "Kinesin-like protein KIF21A", "aln": "MLGAPDESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIVEEELGIISRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQIDA----DNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSD--KETIEIIDLAKKDLEKLKRKEKRKKKRLQKLEESNREE---RSVAGKEDNTDTDQEKKEEKGVSERENNE-LEVEESQEVSDHEDEE-EEEE--EEEDDIDGGESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALPTPATNGNRKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAELNPELDALLGHALQDLDSVPLENVEDSTDEDAPLNSPGSEGSTLSSDLMKLCGEVKPKNKARRRTTTQMELLYADSSELASDTSTGDASLPGPLTPVAEGQEIGMNTETSGTSAREKELSP-PPGLPSKIGSIS----RQSSLSEKKIPEPSPVTRRKAYEKAEKSKAKEQKHSDSGTSEASLSPPSSPPSRPRNELNVFNRLTVSQGNTSVQQDKSDESDSSLSEVHRSSRRGIINPFPASKGIR---AFPLQCIHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGQVTLGDACSASTSRTVAIPSGENQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISSGQDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALTIQGDNLFSGSRDNGIKKWDLTQKDLLQQVPNAHKDWVCALGVVPDHPVLLSGCRGGILKVWNMDTFMPVGEMKGHDSPINAICVNSTHIFTAADDRTVRIWKARNLQDGQISDTGDLGEDIASN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QXL2-1", "uniprot_id": "KI21A_MOUSE", "id": "Q9QXL2-1", "name": "Kinesin-like protein KIF21A", "aln": "MLGAADESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYTQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNIMEEEQGIISRAVRHLFKSIDEKKTSAIKNGLPPPEFKVNAQFLELYNEEVLDLFDTTRDIDAKNKKSNIRIHEDSTGGIYTVGVTTRTVNTEPEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQTDA----ENATDNKLISESSPMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEITRLQMELMEYKTGKRIIDEEGVESINDMFHENAMLQTENNNLRVRIKAMQETVDALRARITQLVSEQANQVLARAGEGNEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARSPYFSASSAFSPTILSSD--KETIEIIDLAKKDLEKLKRKEKKKKKRLQKLEESGREE---RSVAGKDDNADTDQEKKEEKGVSEKENNE-LDVEENQEVSDHEDEE-EEEEDEEEEDDIEGEESSDESDSESDEKANYQADLANITCEIAIKQKLIDELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGSVESYSEEKAKKVKCEYEKKLHAMNKELQRLQTAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRLLEAQKRNQEVVLRRKTEEVTALRRQVRPMSDKVAGKVTRKLSSSESPAPDTGSSAASGEADTSRPGTQQKMRIPVARVQALPTPTTNGTRKKYQRKGFTGRVFTSKTARMKWQLLERRVTDIIMQKMTISNMEADMNRLLRQREELTKRREKLSKRREKIVKESGEGDKSVANIIEEMESLTANIDYINDSIADCQANIMQMEEAKEEGETLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQLLFHMLKEKAELNPELDALLGHALQDLDGAPPENEEDSSEEDGPLHSPGSEGSTLSSDLMKLCGEVKPKNKARRRTTTQMELLYADSSEVASDTSAGDASLSGPLAPVAEGQEIGMNTETSGTSARDKELLA-PSGLPSKIGSIS----RQSSLSEKKVPEPSPVTRRKAYEKADKPKAKEHKHSDSGASETSLSPPSSPPSRPRNELNVFNRLTVPQGTPSVQQDKSDESDSSLSEVHR----GIINPFPACKGVR---ASPLQCVHIAEGHTKAVLCVDSTDDLLFTGSKDRTCKVWNLVTGQEIMSLGVHPNNVVSVKYCNYTSLVFTVSTSYIKVWDIRESAKCIRTLTSSGQVTLGEACSASTSRTVAIPSGESQINQIALNPTGTFLYAASGNAVRMWDLKRFQSTGKLTGHLGPVMCLTVDQISNGQDLIITGSKDHYIKMFDVTEGALGTVSPTHNFEPPHYDGIEALAIQGDNLFSGSRDNGIKKWDLAQKGLLQQVPNAHKDWVCALGLVPGHPVLLSGCRGGILKLWNVDTFVPVGEMRGHDSPINAICVNSTHVFTAADDRTVRIWKAHNLQDGQLSDTGDLGEDIASN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F8W409-1", "uniprot_id": "F8W409_DANRE", "id": "F8W409-1", "name": "", "aln": "----MDDSTVRVALRIRPQLAKEKIEGCHICTFVMPDEPQVVLGKDKAFTYDYVFDMDSTQDNIYSNCTEKLIEGCFEGYNATIFAYGQTGSGKTYTMGTGFDVAIPDEDLGIIPRAVTHLFKGIEQRRQQAAEQSRPVPEFKISAQFLELYNEEVLDLFDTTRDMESRKQKSHIKIHEDASGGIYTVGVTTRNVSSEAEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHICQIRVCAPADSPPEQDNETDNRLAGSSSEMEEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALGNVISALGDRSKRSTHVPYRDSKLTRLLQDSLGGNSRTVMIACISPSDQDFMETLNTLKYANRARNIKNKVMVNQDRASQQISALRTEIARLQMELMEYRTGKRMVGEDGLESINDMFHENSMLQVENNNLRMRVKAMQEAIDAQGARLTQLLSQQANQLLARAGEGSEEIGNMIQNYIKEIEDLRAKLLESEAVNENLRRNLTRASSRPQFYGASGSFSTALLGPDPSQETSDIIEIAKKDLEKLKRREKKKKKRLQQLLADKRDEDEDEEEEVEEDSANKDETQEDGEQKTEKEQSESTNQEPEMEASDREEGDGEEDEEDVEEEEMEAEESSEETDSELDEKEDFQADLANITCEIAIKQKLIDELENSQRRLHTLKQQYEHKLMMLQSKIRDTQLERDRVLHSMGSVESCSEDKTKRIKAEYEKKLSVMNKELQKLQAAQKEHARLLKNQSQYEKQLKKLQLDLTEMKKTKVRLMKQMKEQQEKSRMAESRRNREIATLKKDQRKQEHQLKLLEAQKRQQELILRRKTEEVTALRRQVRPIS----GKVTRKANLSE-PNFDLSHRPPAGRTYGSG--------------------APNGTRLYHRR---AAGIYSTRVARGKWQSLERRISDIIMQRMTISNMEADMNRLLKQREELTRRRDKISRKRERLLADDPEVEKHLQPVNEELESLLANIDYINDSISDCQANIMQMEEAKEEGDAVDVSAVISSCTLAEARFLLDHFMSMALNKGLQAAQKESQIKVMEGRLKQTEINSATQNQLLFHMLKEKAEFNPELDALLGNALQELGNVPLENGDDSSSDESTP-SPAVEGNTLASDLMKLCGETKSRTKARRRTTTQMELLYVDS---GQDAATKDFTIP--LHPMAETSEGSGELESAGNTVRDRDYMPSPAGLTSRMGGISSSGNRFPAGGQKRLPEPSPLSRRKTYDKG-------QAQADKAKSKEILQ-------------------------------------------------GIINPVPVWKSARGGGGGTLQCVHVAEGHSKAVLCVESTDDLMFTGSKDRTCKVWNLVTGQEIMSLGGHPNNVVSVRYS--SSLVFTVSTSYIKVWDIRDSAKCIRTLTSSGLVNTGDMCAASTNRTVTIPAGENQINQIYLNPSGTVLYAAAGNSVRVWDLRRFVCTGKLTGHLGPVMCLTVDQTGNGQDLVITGSKDHYIKMFDVTEGAMGSISPTHNFEPPHYDGIESLVVQGDCLFSGSRDNGIKKWDLTRKDLLQQVPNAHRDWVCALGVVPASAILLSGCRAGVLKLWHTDTLSPLGEIRGHESPINSISTNSTHLFTAADDRTVKIWRARGSLDG-SADVGDTMEEGVSN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*:****:****************** * *.****.********:*****:** *::** :* **************:*******:************ * :*: ***.*** ****.*:::: * ::. * *:**:.********************::::.:**:*:****::***********.*.:*.**********************************:** ***. *: :* ***:: ..*: *:****************************************************:***:**********************:*:****:****:*********************************.***:**:*********:****::.*:*:**********:***.******:*:*****::** :*:***:*:***::*******.***.***:.***********************:*****::*. ::..*.:**.::*..* :** :**::**********:**:******:* . *:* .. ::*.::.*: ::: : :*:*:.* : * . *.**:*: : **:* **::::. ***:*:*** *** ::*************************:**:***:***.****** **********:**:.:***** **:*:*:::.****** .******:**:*********************** *: ***************:***:*::********* *******::***:*******:**::*****************:* ****** . *: * * . ..: .: * :.**.* ::* :. :: ::.** *** ****::*****:**************:******:**:*:*::**::: :. * :* : : **:*** **********:****************:::**:***.:***:***:*****:**.:**********:****:*********.*****************:*********:***:*...* ** :**:.::.. **. **.**:*********.*.:.**************.** ..*::: * ::. * *:** .* . : *::*.:.*::: . *.**.*::*.** * .: .:*::*****::***:*:*. : ::*.. *: *. *****.*. *. * . .***:*:****:******:*****:************************ ********:*. :*****************:************ *. *: *:***.***:**:**.***** ***:**.****:**:**:***:** .****************** ..****:******************:*::***************:*.:*** ***************::*.*********:*******:** .:******.*:**:*: **: *:**::**:****:*..****:*********:**:*:. ** :*.** *: .**", "identical_positions": 1112, "similar_positions": 350, "identity": "65.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-241", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BS95-1", "uniprot_id": "GPHR_MOUSE", "id": "Q8BS95-1", "name": "Golgi pH regulator", "aln": "MSFLIDSSIMITS---------QILFFGFGWLF-------------------------------FMRQLFKDYEVRQYVVQVIFSVTFAFSCTMFELIIFEILGVLNSS--------SRYFHWKLNLCVILLILVFMVPFYIGYFIVSNIQ--LLHKQRLLFSCLLWLTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDTDILALERR-----------LLQTMDMIISKKKR---MAVARRTMFQR---GDVQNKPSGLWGMLKSVTASAPGSENLTLIQQEVDALEELSRQLFLETADLYATKERIEYSKTFKGKYFNFLGY-------FFSIYCVWKIFMATINIVLDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKS--------------------------SNVIVLLLAQIMGMYFVSSVLLIRMSMPPEYRTIITEVLG---ELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKHMAP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1LTD0-1", "uniprot_id": "F1LTD0_RAT", "id": "F1LTD0-1", "name": "", "aln": "MSFLIDSSIMITS---------QILFFGFGWLF-------------------------------FMRQLFKDYEVRQYVVQVIFSVTFAFSCTMFELIIFEILGVLNSS--------SRYFHWKMNLCVILLILVFMVPFYIGYFIVSNIQ--LLHKQRLLFSCLLWLTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDTDILALERR-----------LLQTMDMIISKKKR---MAVTRRTMFQR---GDVQNKPSGLWGMLKSVTASAPGSENLTLIQQEVDALEELSRQLFLETADLYATKERIEYSKTFKGKYFNFLGY-------FFSIYCVWKIFMATINIVLDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKS--------------------------SNVIVLLLAQIMGMYFVSSVLLIRMSMPPEYRTIITEVLG---ELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKHMAP-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "B7ZAQ6-1", "uniprot_id": "GPHRA_HUMAN", "id": "B7ZAQ6-1", "name": "Golgi pH regulator A", "aln": "MSFLIDSSIMITS---------QILFFGFGWLF-------------------------------FMRQLFKDYEIRQYVVQVIFSVTFAFSCTMFELIIFEILGVLNSS--------SRYFHWKMNLCVILLILVFMVPFYIGYFIVSNIR--LLHKQRLLFSCLLWLTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDTDILALERR-----------LLQTMDMIISKKKR---MAMARRTMFQK---GEVHNKPSGFWGMIKSVTTSASGSENLTLIQQEVDALEELSRQLFLETADLYATKERIEYSKTFKGKYFNFLGY-------FFSIYCVWKIFMATINIVFDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKS--------------------------SNVIVLLLAQIMGMYFVSSVLLIRMSMPLEYRTIITEVLG---ELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKQMAP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CG08-1", "uniprot_id": "GPHRB_HUMAN", "id": "P0CG08-1", "name": "Golgi pH regulator B", "aln": "MSFLIDSSIMITS---------QILFFGFGWLF-------------------------------FMRQLFKDYEIRQYVVQVIFSVTFAFSCTMFELIIFEILGVLNSS--------SRYFHWKMNLCVILLILVFMVPFYIGYFIVSNIR--LLHKQRLLFSCLLWLTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDTDILALERR-----------LLQTMDMIISKKKR---MAMARRTMFQK---GEVHNKPSGFWGMIKSVTTSASGSENLTLIQQEVDALEELSRQLFLETADLYATKERIEYSKTFKGKYFNFLGY-------FFSIYCVWKIFMATINIVFDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKS--------------------------SNVIVLLLAQIMGMYFVSSVLLIRMSMPLEYRTIITEVLG---ELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKQMAP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FB29-1", "uniprot_id": "E7FB29_DANRE", "id": "E7FB29-1", "name": "", "aln": "MSFFVDSVIMFTS---------QVLFFGFGWLF-------------------------------FMRQLFKDYEVRQYVVQVVFSITFAFSCTMFELIIFEILGALSSS--------SRYFHWKLNLYVILLVLIFVVPFYIGYFVVSNIR--LLQRQRLLFSCVVWFTFMYFFWKLGDPFPILSPKHGILSIEQLISRVGVIGVTLMALLSGFGAVNCPYTYMSYFLRNVTDSDILALERR-----------LLQTMDMIVSKKKR---IAMTRRQMYQR---GEEQNKQTGFWGMIKSVTSSPSGSENLSLIQQEVDALEELSRQLFLETVDLQATKERIEYSKTFQGKYFNFLGY-------FFSIYCVWKIFMATINIVFDRVGKTDPVTRGIEITVNYLGIQFDVKFWSQHISFILVGIIIVTSIRGLLITLTKFFYAISSSKS--------------------------SNVIVLVLAQIMGMYFVSSVLLMRMSMPLEYRSIVSEVLG---ELQFNFYHRWFDVIFLVSALSSILFLYLAHKQAPEKHMAL-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38799-1", "uniprot_id": "YHN8_YEAST", "id": "P38799-1", "name": "Uncharacterized protein YHR078W", "aln": "MEALIVFIVLSVSGAFAYKCSYERLWFKVGSLFDIISTSSKKNVIPLASKMEVGSNEDVSSMGNFINKFYTEYSLPSHKVLQSLRVLFSLAMMTYTVTIEIILWQIKVAGMDKEVTFITTWVWPLTAIMLSFILILFQPFFIIISLLNKFYNDKFDIDRLIIVTCIILSTLIALLSYINIGPFQYTKN-------ILTRLSIGGVTVMASLSGLATVSSLYYNFLVIWHKFRNTPMSDPSFRNINNSNNNSKSLLWTTDAYIEEKIQDYEHNIEQNVQILRSLEEEVGENSTFKAELMEKIAWYQLELGKLEALLQQSPQVRTFKKAFEVGFIIYCLHKLIITFLKRIPYIIYHSLKYPDDYDYENFSENAASDPLAITIANILDFSFFRFNYQHDLDSLTKQISLFLSISLFLCCLSAVNTTISYVVTLLPIKFQILALFAMQNDDTANVLPEYTNNSSYKGKKRNYSQEQKGISLIKNLVVSELTGVYVLATTLMVRSHLPFEVSQRLKELLGGKFTVPNIVIDSWFDEVYAFACVFTFICIRIAERKLSTKKVSVE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :: :: .* : *:* .* ** *:.:::.:*.: .: * : : *::: : : * ** :. : : * :. :: ::*::. **:* ::.:: :. :**:: : :: : : . : *: .*: :::*:.: ***:** ***:.:*.. * : : ::. :: : . * ** * * :.:* : : :. : : :: : :::.:: :* : *: :. :.: : : * * : * : :: * * ** .. . : ** ::* :.:: .: :.: :.:.:: :* : . * *.:: : : : :* ....: * : *::::: *:*.:::.*::* :* * :.*:** : . . *** :: .:.: ::: : :*.:: . *::: ", "identical_positions": 72, "similar_positions": 189, "identity": "12.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-243", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R9C8-1", "uniprot_id": "M0R9C8_RAT", "id": "M0R9C8-1", "name": "", "aln": "MWLAKLSTRVLLLLLLALALSPPGTQ-------------------G-RPRGRRAARVT--ELLPQLFLPVTGTRLAPR--TSRSTEIFPRDLTLKDKFIKHFTG-PVTFSAECSKHFHRLYHNTRDCSMPAYYKRCARLLTRLAVSPLCSQT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "J3QPP8-1", "uniprot_id": "ALKL1_MOUSE", "id": "J3QPP8-1", "name": "ALK and LTK ligand 1", "aln": "MWLTKPSTPVSALLLLALALSPPGTQ-------------------G-RPQRSLAARVA--ELRPELFLPVTGTRLPPR--ASRSTEIFPRDLTLKDKFIKHFTG-PVTFSAECSKHFHRLYHNTRDCSTPAYYKRCARLLTRLAVSPLCSQT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UXT8-1", "uniprot_id": "ALKL1_HUMAN", "id": "Q6UXT8-1", "name": "ALK and LTK ligand 1", "aln": "MRPLKPGAPLPALFLLALALSPHGAH-------------------G-RPRGRRGARVTDKEPKPLLFLPAAGAGRTPS--GSRSAEIFPRDSNLKDKFIKHFTG-PVTFSPECSKHFHRLYYNTRECSTPAYYKRCARLLTRLAVSPLCSQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F8W2C9-1", "uniprot_id": "ALKL1_DANRE", "id": "F8W2C9-1", "name": "ALK and LTK ligand 1", "aln": "MRAEKRWHILLSMILLLITSSQCMDSKEVKESERKTLLNLILQVIGEKPASRRVTSGLYSVSQDAKFSSRENTAHLPKPDNSRPIEIVPRDTSMKDKFIEHFTAGPVKFPSECRTHFHRIYHNTRDCSRPTYYKRCARLLTRLAMSPLCTQS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * : ::** :: * * :* : * . .: * **. **.*** .:*****:***. **.*..** .****:*:***:** *:*************:****:*:", "identical_positions": 58, "similar_positions": 27, "identity": "38.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-244", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZM3-1", "uniprot_id": "CLCF1_MOUSE", "id": "Q9QZM3-1", "name": "Cardiotrophin-like cytokine factor 1", "aln": "MDLRAGDSWGMLACLCTVLWHLPAVPALNRTGDPG-PGPSIQKTYDLTRYLEHQLRSLAGTYLNYLGPPFNEPDFNPPRLGAETL--PRATVNLEVWRSLNDRLRLTQNYEAYSHLLCYLRGLNRQAATAELRRSLAHFCTSLQGLLGSIAGVMATLGYP-LP-------------------------------------------------------------------------------------------------------------------------------QPLPGTEPAWAPG-----------------------------------------PAHSDFLQKMDDFWLLKELQTWLWRSAKDFNRLKKKMQPPAASVTLHLEAHGF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBD9-1", "uniprot_id": "CLCF1_HUMAN", "id": "Q9UBD9-1", "name": "Cardiotrophin-like cytokine factor 1", "aln": "MDLRAGDSWGMLACLCTVLWHLPAVPALNRTGDPG-PGPSIQKTYDLTRYLEHQLRSLAGTYLNYLGPPFNEPDFNPPRLGAETL--PRATVDLEVWRSLNDKLRLTQNYEAYSHLLCYLRGLNRQAATAELRRSLAHFCTSLQGLLGSIAGVMAALGYP-LP-------------------------------------------------------------------------------------------------------------------------------QPLPGTEPTWTPG-----------------------------------------PAHSDFLQKMDDFWLLKELQTWLWRSAKDFNRLKKKMQPPAAAVTLHLGAHGF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6T6-1", "uniprot_id": "A0ACD6B6T6_DANRE", "id": "A0ACD6B6T6-1", "name": "Cardiotrophin-like cytokine factor 1", "aln": "---MCPWKVGQVAVLLLLAVMVGNAQVLDRTLILSNERSSIERTYELTKYLDHQLKEIRDTYLSYLGPPFSHPGFSPPRPNSSSLSVPSAATRVDLWRGLENGARLAQNQHAYSILLCAVRELARSTLCPYLQSSLLHFCSGLSGLLGSISGLMNALGYTNLPSSAGYATPAQGYAPAMSSQFQGVSENSPAPLRSYVPRNQGAKTVSGVREGTTRADLKRDREKERAERGRRGRRKEGESWVAKEEGEKEEGMERWGKRRRLLSMDEEKTIKLNNMNYTSLKFGDGYRKQPLLFSTPSLHPRRSVRSIPSSHSGLSPLSLLYQYGGPVSEVHTLLAAPVLSSHPTANDFSRKVEGFWVLRELQSWLWRSAKDFTRLKKRLRV--------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * :* * : : . .*:** . .**::**:**:**:***:.: .***.******..*.*.*** .:.:* * *:. :::**.*:: **:** .*** *** :* * *.: . *: ** ***:.*.******:*:* :***. ** *** : *: * *: .** :*::.**:*:***:*********.****::: ", "identical_positions": 98, "similar_positions": 65, "identity": "24.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-249", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60299-1", "uniprot_id": "LZTS3_HUMAN", "id": "O60299-1", "name": "Leucine zipper putative tumor suppressor 3", "aln": "------------------------------MAKLETLPVRADPGRDPLLAFAPRPSELGPPDPRLAMGSVGSGVAHAQEFAMKSVGTRTGGGGSQGSFPGPRGSGSGASRERPGRYPSEDKGLANSLYLNGELRGSDHTDVCGNVVGSSGGSSSSGGSDKAPP----QYREPSHPPKLLATSGKLDQCSEPLVRPSAFKPVVPKNFHSMQNLCPPQTNG--TPEGRQGPGGLKGGLDK--SRTMTPAGGSGS--GLSDSGRNSLTSLPTYSS---SY--SQHLAPLSASTSHINRIGTASYGSGSGGSSGGGSGYQD-LGTSDSGRASSKSGSSSSMGRPGHLGSGEGGGGGLPFAACSP-PSPSALIQELEERLWEKEQEVAALRRSLEQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVARRAQRAQQGLQLQVLRLQQDKKQLQEEAARLMRQREELEDKVAACQKEQADFLPRIEETKWEVCQKAGEISLLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQLLSLRDSFSSKQASLELGEGELP-------------------AACLKPALTPVDPAEPQDALATCESDEAKMRRQAGVAAAAS-------------LVSVDGEAEAGGESGTRALRREVGRLQAELAAERRARERQGASFAEERRVWLEEKEKVIEYQKQLQLSYVEMYQRNQQLERRLRERGAAGGASTPTPQHG------------EEKK---------AWT-PSRLERIESTEI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2AHG0-1", "uniprot_id": "LZTS3_MOUSE", "id": "A2AHG0-1", "name": "Leucine zipper putative tumor suppressor 3", "aln": "MAPADLASEGPKLEDPPAPHLFGKCPSGLIMAKLETLPVRADPGRDPLLAFAPRPSELGPPDPRLTMGSVGSGVTHAQEFPMKSVGTRTGGGGNQGSFPGPRSGGSGANRERPGRYPSEDKVLANSLYLNGELRGSDHTDVCGNVVGSSGGSSSSGGSDKAPP----QYREPNHPPKLLTTSGKLDQCSEPLVRPSAFKPVVPKNFHSMQNLCPPQTNG--TPEGRQGPAGLKGGLDK--SRTMTPAGGSGG--GLSDSGRNSLTSLPTYSS---SY--SQHLAPLSASTSHINRIGTAGYSSG---SSGGGSGYQD-LGTSDSGRASSKSGSSSSMGRSGHLGSGEGGNGGLPFAACSP-PSPSALIQELEERLWEKEQEVAALRRSLEQSEAAVAQVLEERQKAWERELAELRQGCSGKLQQVARRAQRAQQGLQLQVLRLQQDKKQLQEEAAQLIRQREELEDKVAVCQKEQADFLPRMEETKWEVCQKAGEISLLKQQLKDSQADVSQKLSEIVGLRSQLREGRASLREKEEQLLSLRDSFGSKQASLELSEGELP-------------------PACLKPALTPVDLVEPQEALASCESDEAKMRRQAGVAAAAS-------------LVSVDGEVEAGGEGGTRALRREVGRLQAELAAERRARERQGASFAEERRVWLEEKEKVIEYQKQLQLSYVEMYQRNQQLERRLRERGAAGGSSTPTPQHG------------EEKK---------AWT-PSRLERIESTEI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F179-1", "uniprot_id": "E7F179_DANRE", "id": "E7F179-1", "name": "", "aln": "---------------------MGSVGSG--VAGEQEFAMKS-VGTRTTLPRGPPLSRRGPSDR-------SCSAERLHPHPSTSEGSSDERGGSSTTTDRVLERGQLNMERVPANLDALEGTAAGRRDGHRSGRG-VSLDACGNVVGHGAEKNHDGAAPLKSRDGNISKRDGRTPPKILTVSGKLEQNTSALVRPSAFKPVVPKSFHSMQNLVGQSGSGGGRSAGSGGGSDAPQSLCEQDSPERDPSGGNDGQGGMSDSGRNSLTSLPTYAGPSLSYGPAQALGPLSASTSHINRLSSAAAPLE----KGEKPKYQNGLSVSDSGQSSS-GKSCLSYHRLCHLT--------EPSATVQPSPSTDDIIQDLEDRLWEKEQEVIHMRRNLDQSEAAIAQVFEEKQRVWEREMEDLRQNYAGRLQQVTHRAQRTQHALQTHIARLQQDKGRLQEEISALLAQREELERKCLDYRKEQADILPRLEETKWELCQKAGEISLLKQQLRESQNEVTQRAGETVALRGQMKDLNAQLKEREDTMIGLKDSYNSKSRELERCEGELKRTLAEVSMLRDKLVVFESEVVGLKRALNELSCRSDHTAVLSSISGSSSLP-WAGLHSPRTPEPLSVLGSTVETFLSLQSDEAKAQRQEAGELRRQLERLQGELHLEKQQRERQALTFAQERHTWQDEKERVLKYQAQLQLSYVETLQRNQALEERVGQLGAKMAPGSPPPISLSIPVPVTVTLSPDELKPPVLHQLAPPWPGPSRLERIESTEI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : :.::: * . *. .* *. **.* .... : : .. .* *: **.. : *. .. *.. : : *. : . ** *.****** .. .. .*.: . . *: ***:*:.****:* :..*************.******* . .* . * * .. .* : * *:**... *:**************:. ** :* *.***********:.:*. .* . **: *..****::** . *. * * ** * *: .* **.. :**:**:********* :**.*:*****:***:**:*:.****: :***. :*:****::****:*:.** :: ****** :**** : *: ****** * :*****:***:******:**************::** :*:*: .* *.**.*::: .*.*:*:*: ::.*:**:.**. .** **** . ** **. :. . : *: :. *..:.: **: :. : ::*::.: . . : ***:: ***.** *:: ****. :**:**:.* :***:*::** ******** **** **.*: : ** ...:*.* :* * .*. ************", "identical_positions": 297, "similar_positions": 193, "identity": "38.37%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-25", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BGV4-1", "uniprot_id": "TTI2_MOUSE", "id": "Q8BGV4-1", "name": "TELO2-interacting protein 2", "aln": "MKLDSAEEK-SGVGCSLPAEGSPPALEPAFSKILNRLSRPKSSGQGGARNAALKDLGALIEAAEGDRFFEGSGSGGSLRGMPEILGQVVRALEKFAAP-EEKADG---VEEHPEVPEKATEVGSLFLKLLGKVEAAKSSPDCPAWKTGLRHMSGPVYIFAITHRLKQPWTSPASQHVAGEVLSLLLRVTECSSVAGFLCGE-NEDDRGRFAVVLGLLKPHLNKETWKKNPAVKHVFSWTLQQVTQPWLNQHLEKILPPSLLISDDYQTENKILGVQCLHHIVVTVPAADLLQYNRAQVLYHALFNHLYMPEHHLIQAVLLCLLDLFPVLEKALHWKGDTARVTTHCHEVLQLILTHMEPEHRLLLRRTYARHLPAFVKRLGILTVRHLKRLEQVILGYLEVYDEPEDETRLKILETLKLVMQYTWPRIPCRVVVLLKALLKLICDISRDTIPTTEAAKSTMLQEATDCLILLDHCSQGQVKGLLAKIAVSCEDSTVVSCIRKVQQGSADSPGDDTEGD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NXR4-1", "uniprot_id": "TTI2_HUMAN", "id": "Q6NXR4-1", "name": "TELO2-interacting protein 2", "aln": "MELDSALEAPSQEDSNLSEELSHSAFGQAFSKILHCLARPEAR-RGNVKDAVLKDLGDLIEATEFDRLFEGTG--ARLRGMPETLGQVAKALEKYAAPSKEEEGG---GDGHSEAAEKAAQVGLLFLKLLGKVETAKNSLVGPAWQTGLHHLAGPVYIFAITHSLEQPWTTPRSREVAREVLTSLLQVTECGSVAGFLHGE-NEDEKGRLSVILGLLKPDLYKESWKNNPAIKHVFSWTLQQVTRPWLSQHLERVLPASLVISDDYQTENKILGVHCLHHIVLNVPAADLLQYNRAQVLYHAISNHLYTPEHHLIQAVLLCLLDLFPILEKTLHWKGDGARPTTHCDEVLRLILTHMEPEHRLLLRRTYARNLPAFVNRLGILTVRHLKRLERVIIGYLEVYDGPEEEARLKILETLKLLMQHTWPRVSCRLVVLLKALLKLICDVARDPNLTPESVKSALLQEATDCLILLDRCSQGRVKGLLAKIPQSCEDRKVVNYIRKVQQVSEGAPYNGT---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F592-1", "uniprot_id": "E7F592_DANRE", "id": "E7F592-1", "name": "", "aln": "-----------MRELNIRDSTGFCSIHAALSHIQERFESEDTH---DKRASILEDTIELLTGAPLDWLFPEVN--ADLRG--QYLRLVNSFTCYAALPVCETDSGTLPAQSYESIPVKSQAVSAVLLALSAQIEKFLVKQNGASIKSLVRTLAPSLYIFAVTHLHKHPWTDGPSRKKASELLTALLRMTGSGSVQELLSGKPDVAKKGVFGPVLHTLQSELTQKNWKRNQAVKHVFSTTLVQVEQPWLTDYLENVFPPSLLISDDYHIENKILGVHCLHHIVLNVPAADLRQFNRAQVLYHTLFNHLYTSEAALVQVVLPCLIDLLPILEKSSAHAS-FPCISNRFDDLLCHILTYMEMEHKLDLRQVYAKNLVLLIDRMGISVIRHLKRLERVIVGYMEVSDAPEEKARLSILDALQKTLQIAWPRMEKRRDSLAQSLLRFLVDVSSDS--SPTELKEQLMTKASHCLLLLVHCSKGKLQALLREVDSSCVPDPVFKCIQNVLAASCP---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . . :: *:*:* . : .: . : : *:* *: .: * :* . . *** : * * * * * .* : : . . *: *. ::* * .::* . .: :: :: :: .:****:** ::*** *:. * *:*: **::* ..** :* *: : .:* :. :* *:..* ::.**.* *:***** ** ** :***.::**.::*.**:*****: *******:******:.****** *:********:: **** .* *:*.** **:**:*:***: . . :.: .::* ***:** **:* **:.**::* ::.*:** .:*******:**:**:** * **:::**.**::*: :* :***: * * ::**::: *:: *. :. *. :: :*:.**:** :**:*:::.** :: ** *.. *::* * ", "identical_positions": 182, "similar_positions": 158, "identity": "35.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-253", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O95395-1", "uniprot_id": "GCNT3_HUMAN", "id": "O95395-1", "name": "Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3", "aln": "MVQWKRLCQLHYLWALGCYMLLATVALKLSFRLKCDSDHLGLESRESQSQYCRNILYNFLKLPAKRSINCSGVTRGDQEAVLQAILNNLEVKKKR-EPFTDTHYLSLTRDCEHFKAERKFIQFPLSKEEVEFPIAYSMVIHEKIENFERLLRAVYAPQNIYCVHVDEKSPETFKEAVKAIISCFPNVFIASKLVRVVYASWSRVQADLNCMEDLLQSSVPWKYFLNTCGTDFPIKSNAEMVQALKMLNGRNSMESEVPPKHKETRWKYHFEVVRDTLHLTNKKKDPPPYNLTMFTGNAYIVASRDFVQHVLKNPKSQQLIEWVKDTYSPDEHLWATLQRARWMPGSVPNHPKYDISDMTSIARLVKWQGHEGDIDKGAPYAPCSGIHQRAICVYGAGDLNWMLQNHHLLANKFDPKVDDNALQCLEEYLRYKAIYGTEL----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RAK7-1", "uniprot_id": "F1RAK7_DANRE", "id": "F1RAK7-1", "name": "Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 3", "aln": "-------MGINNQRTLKTVSILS-VSITLFVLVMNYPEQSCLPKRETN-------LNHLQQQDVGELQACSAIIQGDMDGVDKESFRKLLASKKRPSLLTESFYLNITTDCPTYIEGRGFLMEALSKEEEDFPIAYSMVIHDKIEMFERLLRAIYAPQNVYCVHVDMKSPQIFREAVNAIVSCFPNVFVASKLESVIYASWSRVQADVNCMQDLLKSPVQWRYLLNTCGTDFPIKTNAETVRSLKHLNGKNSMESETVP-GKNWRWQFHHNIT-NTVIRTDIRKSPPPINTSMFSGNAYFVVSREFVEYIMNSKEIQNLMEWEKDTYSPDEHMWATLQRMPSVPGSNSPNNKYEQSDMNAIARLVKWSYHEGDLNSGAPYPPCTGMHRRSVCVYGAGDLKWIVRQHHLLANKFDPEVDDVAIKCMEAFLRYKAVYGRSLLTVRKSDFVL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :* :*: *::.* . : .:: * .**:: * :: : . . **.: :** :.* : :.:* ..*** . :*::.**.:* ** : * *: .***** :**********:*** *******:*****:****** ***: *:***:**:*******:**** *:**********:***:***:*.* *:*:***********:*** *::** ***:******. * *: **::*.::. :*: *: :*.*** * :**:****:*.**:**:::::. : *:*:** *********:****** :*** . : **: ***.:*******. ****::.****.**:*:*:*::********:*::::**********:*** *::*:* :*****:** .* ", "identical_positions": 231, "similar_positions": 118, "identity": "51.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-262", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60779-1", "uniprot_id": "S19A2_HUMAN", "id": "O60779-1", "name": "Thiamine transporter 1", "aln": "MDVPGPVSRRAAAAAATVLLRTARVRRECWFLPTALLCAYGFFASLRPSEPFLTPYLLGPDKNLTEREVFNEIYPVWTYSYLVLLFPVFLATDYLRYKPVVLLQGLSLIVTWFMLLYAQGLLAIQFLEFFYGIATATEIAYYSYIYSVVDLGMYQKVTSYCRSATLVGFTVGSVLGQILVSVAGWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFHHIPSTCQRVNGIKVQNGGIVTDTPASNHLPGWEDIESKIPLNMEEPPVEEPE-PKPDRLLVLKVLWNDFLMCYSSRPLLCWSVWWALSTCGYFQVVNYTQGLWEKVMPSRYAAIYNGGVEAVSTLLGAVAVFAVGYIKISWSTWGEMTLSLFSLLIAAAVYIMDTVGNIWVCYASYVVFRIIYMLLITIATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVVDASGLGLEITTQFLIYASYFALIAVVFLASGAVSVMKKCRKLEDPQSSSQVTTS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9EQN9-1", "uniprot_id": "S19A2_MOUSE", "id": "Q9EQN9-1", "name": "Thiamine transporter 1", "aln": "MDVPARVSRRAAAAAARMLLRTARVPRECWFLPTALLCAYGFFANLRPSEPFLTPYLLGPDKNLTERQVYNEIYPVWTYSYLLLLFPVFLATDYLRYKPVILLQGLSLIVTWFMLLYAQGLLAIQFLEFFYGIATATEIAYYSYIYTVVDLGMYQKVTSYCRSATLVGFTVGSVLGQILVSVVGWSLFSLNVISLTCVSVAFAVAWFLPMPQKSLFFHHIPSSCHGVNGLKVQNGGIVTDTPAANHLPGWEDIESKIPLNLDEPPVEEPEEPKPDRLRVFRVLWNDFLMCYSSRPLLCWSVWWALSTCGYFQVVNYAQGLWEKVMPSQNADIYNGGVEAVSTLLGASAVFAVGYIKLSWSTWGEMTLFLCSLLIAAAVYVMDTVQSIWVCYASYVVFRIIYMVLITIATFQIAANLSMERYALVFGVNTFIALALQTLLTLIVVDARGLGLCITTQFLIYASYFAAISVVFLANGIVSIIKKCRKQEDPSSSPQASTS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F340-1", "uniprot_id": "E7F340_DANRE", "id": "E7F340-1", "name": "", "aln": "MSEP-------------------------WLYPTVLLCIYGFFSSHRPLEAFLMPFLMGPDKNLTETEVVSEIYPLWTYSYLALLFPVFLATDYLRYKPVIILQAASYVVTYALLVKAQGLQAMQIVEVFFGLATATEIAYYSYIYSVVEPSHYQMVTGFCRSVTLLGSAMGSLLGQILFSVADIALFYLCVITLVSFCIAFVAPWFLPMPSKSLFFHQSESSSQDEAVLETVNTSPLIEKP--------EDPESNKQPNANEKTTLKSNTSSSGLLDVLKMLWTDFLQCYSSSTLLAWSVWWALSTCGYLQVINYAQALWEDILTSKNYDIYNGYVETISTLLGAFAAFVVGYVKVSWAVWGELALCIFTVVIAVCVYLMYAVRNIWVCYTSYIIFRAVYMLLITIATYQIAANLSMKRYALVFGVNTFIALSLQMLLTVIVVDSAGLHLEISIQFLIYASYFAAVAVIFFIAGLYKLFRSRTSGGQNELSSAEA--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. * *: **.*** ****:. ** *.** *:*:******** :* .****:****** *****************::**. * :**: :*: **** *:*::*.*:*:*************:**: . ** **.:***.**:* ::**:*****.**.. :** * **:*....:**...******.******: *:.: ::. * . : :.* ** **: * :* .. :.: .... * *:::**.*** **** .**.************:**:**:*.***.::.*: **** **::****** *.*.***:*:**:.***::* : :::**..**:* :* .*****:**::** :**:******:********:**************:** ***:****: ** * *: ********** ::*:*: * .:::. . : . *. : ", "identical_positions": 263, "similar_positions": 129, "identity": "52.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-267", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A193-1", "uniprot_id": "D4A193_RAT", "id": "D4A193-1", "name": "Receptor expression-enhancing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MVSWIISR---------LVVLIFGTLYPAYYSYKAVKSKDIKEYVKWMMYWIIFALFTTAETFTDIFLCWFPFYYELKIAFVAWLLSPYTKGSSLLYRKFVHPTLSSKEKEIDDCLVQAKDRSYDALVHFGKRGLNVAATAAVMAASKGQGALSERLR-SFSMQDLT----------------------------TIRGDGAPAPSGPPPPGSGRSSGKHGQ-------------------------------------PKMSRSASESAGSSVCTCCST------------------------------CRTRKVVEG------------------------------------------------------------------------------------------------------DVSEGGVK------------------SWEPHQ----------VQNPLAFSDEEEEDLLEF---------IYKYKAPRRTEFP------LEAPPRTLR--SRFRKKSTSSSATETT------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGH4-1", "uniprot_id": "REEP1_MOUSE", "id": "Q8BGH4-1", "name": "Receptor expression-enhancing protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MVSWIISR---------LVVLIFGTLYPAYYSYKAVKSKDIKEYVKWMMYWIIFALFTTAETFTDIFLCWFPFYYELKIAFVAWLLSPYTKGSSLLYRKFVHPTLSSKEKEIDDCLVQAKDRSYDALVHFGKRGLNVAATAAVMAASKGQGALSERLR-SFSMQDLT----------------------------TIRGDGAPAPSGPPPPGTGRSSGKHSQ-------------------------------------PKMSRSASESAGSSGTA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H902-1", "uniprot_id": "REEP1_HUMAN", "id": "Q9H902-1", "name": "Receptor expression-enhancing protein 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MVSWIISR---------LVVLIFGTLYPAYYSYKAVKSKDIKEYVKWMMYWIIFALFTTAETFTDIFLCWFPFYYELKIAFVAWLLSPYTKGSSLLYRKFVHPTLSSKEKEIDDCLVQAKDRSYDALVHFGKRGLNVAATAAVMAASKGQGALSERLR-SFSMQDLT----------------------------TIRGDGAPAPSGPPPPGSGRASGKHGQ-------------------------------------PKMSRSASESASSSGTA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P9M3-1", "uniprot_id": "A0A8M9P9M3_DANRE", "id": "A0A8M9P9M3-1", "name": "Receptor expression-enhancing protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------MVSWIISR---------LVVLIFGTLYPAYSSYKAVKSKDVREYVKWMMYWIIFALFTTVEVITDIFLCWLPFYYELKIAFVVWLLSPYTKGSSVLYRKFVHPTLSSKEKDIDEYLCQAKDKSYDTLMHFGRKGLNVAATAAVMAATKGQGVLSERLR-SFSMQDLS----------------------------SFQAEGQTNSASSVT--TQPAAAQHRT-------------------------------------RTMMRSKSETGYSKGHDFDMT------------------------------EYELLNLEQSK----------------------------------------------------------------------------------------EPPIPPTPTPILTLSQPNLP------------------QTEPVTPLPSPPESQDQSSPPTVASEEPQEKEDF---------ISSSPQFRFKRRA------PEPPPRPLRPFTRSRSKNALSSDTEAM------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4JCU3-1", "uniprot_id": "A0A0B4JCU3_DROME", "id": "A0A0B4JCU3-1", "name": "", "aln": "MRPIYQQEPPLFYQRPANLRRLRHPPGTVYGRSYSLEDQPEDVIPVYPKFIYAPQQQQQQQRAPYPLYQLGDSLSSLDSDFPENEYAGAYIVEDRVPLANAPTPKVVQNLNALGRMLELLQRCPLPCLSFNTACICSLIVIFLAPRTCAQSLLFPAFRLFCGTLYPAYASYKAVRTKDVKEYVKWMMYWIVFAFFTCIETFTDIFISWLPFYYEVKVALVFWLLSPATKGSSTLYRKFVHPMLTRHEQEIDEYVNQAKERGYSAVLQLGSKGVNYATNVLMQTAIKGGGNLVQTIKRSYSLSDLSEPDMHRTQDELDDVMMSSMTSSAVVMRSTATGARLLRPRNQTPVGRSGSGTRHSTGMYFTEVDVTAKNAGDFNYNIRSQDDISSGYSSAEPVSGLSRTSSMTNASKARAKSKRNELLEEMRDEVYLDNQLYFQGVQRKSSVPEAEELKIVESSESIQSQELEKVLKEENIDAEDEAFFETLPLIEEHINEVVANYGRDEKLLPQERKHNSIEEEQFEDALFEEPQKCVSDEVDAKNIEEILTDRSQNQTPNGSAETTDSGTPSQNKPYVHPPIDPFLLVLSASASAPDPFMPERPRPMSPREMRETLEEIKHSFRAQLEAEPSVSASPSPSLRPKANHGKGRAPPPPLPPKKHSLSPQPDAISQTSTGSVERKSGIGQLFKNIKANVLRNKANPSQQQPEDEQLAAKETQI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* :: .* . *: ******* *****::**::**********:**:** *.:****:.*:*****:*:*:* ***** ***** ******** *: :*::**: : ***::.*.:::::* :*:* *:.. : :* ** * * : :: *:*:.**: : . . . . :. :* : *: * : *. ", "identical_positions": 88, "similar_positions": 61, "identity": "12.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-272", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BRU4-1", "uniprot_id": "CLC9A_MOUSE", "id": "Q8BRU4-1", "name": "C-type lectin domain family 9 member A", "aln": "-----------MHAEEIYTSLQWDIP--TSEASQKCQSPSKCSGAWCVVTMISCVVCMGLLATSIFLGIKFFQVSSLVLEQQERLIQQDTALVNLTQWQR--KYTLEYCQALLQRS----------LHSGSDCSPCPHNWIQNGKSCYYVFERWEMWNISKKSCLKEGASLFQIDSKEEMEFIS-SIGKLKGGNKYWVGVFQDGISGSWFWEDGSSPLSDLLPAERQ---RSAGQICGYLKDSTLIS------DKCDSWKYFICEKKAFGSCI----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UXN8-1", "uniprot_id": "CLC9A_HUMAN", "id": "Q6UXN8-1", "name": "C-type lectin domain family 9 member A", "aln": "-----------MHEEEIYTSLQWDSP--APDTYQKCLSSNKCSGACCLVMVISCVFCMGLLTASIFLGVKLLQVSTIAMQQQEKLIQQERALLNFTEWKRSCALQMKYCQAFMQNS----------LSSAHNSSPCPNNWIQNRESCYYVSEIWSIWHTSQENCLKEGSTLLQIESKEEMDFITGSLRKIKGSYDYWVGLSQDGHSGRWLWQDGSSPSPGLLPAERS---QSANQVCGYVKSNSLLS------SNCSTWKYFICEKYALRSSV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2K314-1", "uniprot_id": "A0A0G2K314_RAT", "id": "A0A0G2K314-1", "name": "", "aln": "-----------MNEGRLTYAELKSLK--SKDKPQPTQKKREYP--WRISVVILGTVCLCLLISSIVFGYLFFQGTSKFKIQCEKDANKN-------------AVSSKEVVDPSALP----------PTTGKGCYKCQGRWFCCGEKCYYFSEEEKTWDESEASCRLLGSHLAKIDNREEQNFIQ---SRLN--YSYWVGLRKKGGQFLWVHQEDEKISSDLDFHMTT---HLADAACGYIKPKLLNN------AQCSRLFPYICKKNFTCLLTSENW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BWY2-1", "uniprot_id": "CLC1A_MOUSE", "id": "Q8BWY2-1", "name": "C-type lectin domain family 1 member A", "aln": "MQAKYSSTRDMLDDDDTTISLYSGTSTVTRRAEPRHSENGTPSSVWRPVALTLLTLCLVLLVGLAALGLVFFQFYQLSNIQQDSITEKDEKLGNMSRQLQSLQAQNRKLIETLQQVAVKLCRELYNKSGGHRCSPCPEKWKWYGDKCYQFYKESKNWQSCEYFCLADNATMLKISTQEELDFAMP-QSYSEFFYSYWTGLSRNGSGKAWLWTDGTPYSFELFEIIIDPT-NLRNRDCMTIFNGKAYS------KDCKELRRCACERIAGRVVPGELQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6QLQ4-1", "uniprot_id": "CLC7A_MOUSE", "id": "Q6QLQ4-1", "name": "C-type lectin domain family 7 member A", "aln": "--MKYHSHIENLDED-GYTQLDFSTQDIHKRPRGSEKGSQAPSSPWRPIAVGLGILCFVVVVVAAVLG----ALGEYGHNSGRNPEEKDNFLSRNKENHKPTESSLDEKVAPSKAS----------QTTGGFSQPCLPNWIMHGKSCYLFSFSGNSWYGSKRHCSQLGAHLLKIDNSKEFEFIES-QTSSHRINAFWIGLSRNQSEGPWFWEDGSAFFPNSFQVRNTAPQESLLHNCVWIHGSEVYN------QICNTSSYSICEKEL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F7Z4-1", "uniprot_id": "E7F7Z4_DANRE", "id": "E7F7Z4-1", "name": "", "aln": "-----------MQTDKLAEDVEGNPD--RVDPYHQQGK--------VACAMFTVLLLFSFLVIGIVTGFNFKKSPQEDQNRG--------------------LLSDDITPIPFQYK--------------SDKGLCSDGWLLYKNTCYLLENVYGTWKSSKSLCLSRGAHLMVVDSEEELEFIS---RVVQKWTDYWIGLKRDKMG-KWFWVNGDDYHSNLHFWDENQPAHGGMESCVYLKGSDTVNRKLFHDSDCSSQRFHICEHQI---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P37217-1", "uniprot_id": "CD69_MOUSE", "id": "P37217-1", "name": "Early activation antigen CD69", "aln": "-----------MDSENCSITENSSSHLERGQKDHGTSIHFEKHHEGSIQVSIPWAVLIVVLITSLIIALIALNVGKYN---------------------------CPGLYEKLESS-------------DHHVATCKNEWISYKRTCYFFSTTTKSWALAQRSCSEDAATLAVIDSEKDMTFLK----RYSGELEHWIGLKN-EANQTWKWANGKEFNSWFNLTGSG--------RCVSVNHKNVTA------VDCEANFHWVCSKPSR--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q0H8B9-1", "uniprot_id": "CL2DB_RAT", "id": "Q0H8B9-1", "name": "C-type lectin domain family 2 member D11", "aln": "-----------MSAKKASQPMLNTTG----SLQEGEMGKMFHGKCLRIVSPESPAKLYCCYGVIMVLSVAVVALSVALS--------------------------VKMTPQISTIN---------------TYAACPRNWIGVGNKCFYFSEYASNWTFSQTFCKAQEAELARFDTEEELNFLS----RYKGSFDYWIGLHRESSEHPWKWTDNTQYNYSLSIRGVER---YAYLNDIGISSARVYADKR---WSCSKLNSYSLQCKTPFSPM----", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * * .*: . * .: * : : ... :: * .* *: . * :. : *. . ", "identical_positions": 10, "similar_positions": 22, "identity": "3.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-274", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M9B1-1", "uniprot_id": "A0ABK0M9B1_RAT", "id": "A0ABK0M9B1-1", "name": "DNA excision repair protein ERCC-6-like 2", "aln": "-----------MDASAPHPRADSH-KDRWCPGERCLAPSLDNKKLCEASIKSITVDENGEPFAVVLYPDFQEKKIPLQRLQEVKSTKDHSRSLIFDDEDLEKPYFPDQKIPSLVSAFQLSEDGDSIPYTINRYLRDYQREGAQFLYRHYIKGRGCILGDDMGLGKTIQVISFLAAVLHKKGTREDIENNMPEFLLKSMKKES-SSTARKMFLIVAPLSVLYNWKDELDTWGYFRVTVLHGSKKDNELTRLKQRKCEIALTTYETLRLCLEELNSLEWSAIIVDEAHRIRNPNARVTEVMKAVKCKVRIGLTGTILQNNMKELWCVMDWAVPGLLGSRIHFKKQFSDPVEHGQRHTATKRELATGRKAMHRLAKKMSGYFLRRTKTLIKGQLPKKEDRMVYSSLTDFQKAVYQTVLETEDVALILTSSQPCTCGSGQKRRKCCYKTNSQGDTVRTLCLSYLTVLQKVANHVALLQAAS-TSKHQETLIKRICDQVFSRFPDFVQKSKDAAFETLSDPKYSGKMKVLDQLLNHFRKHRDKVLLFSFSTKLLDVLQQYCMASGLDYRRLDGSTKSEERLKIVKEFNSSQDVNICLVSTMAGGLGLNFIGANVVILFDPTWNPANDLQAIDRAYRIGQCRDVKVFRLISLGTVEEIMYLRQVYKQQLHCVVVGSENAKRYFEAVQGSKEHRGELFGVHNLFKLRSQGSCLTRDILETRSQPGELQIISLGFWDFVVKCFIVLHLREGQVEAGIMTATTWLKGEASAQKLETPRDPDCQEP-----------TNVCELYSDMSDEESVG----KAVKHKVSGPSRTPGSSAQLTLLQCGFSKLFEAKCESVQDGDGNPVSSDGSSDEQPMCLSAKARQAACQKTWDSVCTSEHQKSDNIQTPDEKCVSDKSEKTLEQNVSSESDDETKCHSTAGHHCMGQGDTESEDSDVIFPTQDPTQRVPKNPICCKLLLGESEDSETEDPVKVNHDDGRQNSG-RGNGPVSNFLYLENMTLKSVRKRKGTDDISDESDD-IDMFPKSRIRKQRATASLKLKSKKENKRKHYNSPITAKDTNQVCEADGDCSSQVIEDFSSSDDSSSVSHVSFTKLNHRAETVKGKSNLRNKLPGPDKKNNSFIPRKPASFLNERVVSQEQICNSMDKILDGVQEVAYIHSNQNVIGSSRAENHMSRWATRDVFELKQFSQLPANVAVCSSETYKSKVNANAVIPTKKDQPPSDGHISSPLYISHPVSQKKKDVYRTNHTTFIIGETPRGIRRKQFEEMASFYKLS-VKEFAEQVTSATSEEQQRMLRDFYSLQHPEVKEFFMDSASELMKSVHEK-EERVRNKSKGKESLLKERPSNDSTLSCNDSTNKMSQVYNQKICEGKSVRFQNHGSHKEDTFSSGAEIKKSPVNFTQEIYSERNNHTPKDSMTLFCPDSKSEALETELEGSSGHQWDLTGAGSSRNRPCFKLRNKRVENPVSESTPTEGLLGDTSILNDLFKSHGEGPTQLPKNGPSGPVAKAKQRPKDFWDILNEQNDDSLSKLTDLAVIETLCTKAPRTTASKRKEELEAS-LWKANEKFLWKTFSSDVDDESISSRERE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JIM3-1", "uniprot_id": "ER6L2_MOUSE", "id": "Q9JIM3-1", "name": "DNA excision repair protein ERCC-6-like 2", "aln": "-----------MDISAPQSRADSR-KDRWCPGERCLAPSLDNKKLCEASIKSITVDGNGKPFAVVLYPDFQEKTIPLQRLQEVKSTKDYSRSLIFDDKDLEKPYFPDRKIPSLASAFQLSEDGDSIPYTINRYLRDYQREGAQFLYRHYIEGRGCILGDDMGLGKTIQVISFLAAVLHKKGTREDIENNMPEFLLKSMKKKP-PSTAKKMFLIVAPLSVLYNWKDELDTWGYFRVTVLHGSKKDNELLRLKQRKCEIALTTYETLRLCLEELNSLEWSAIIVDEAHRIKNPKARVTEVMKAVKCKVRIGLTGTVLQNNMKELWCVMDWAVPGLLGSRIHFKKQFSDPVEHGQRHTATKRELATGRKAMHRLAKKMSGWFLRRTKTLIKGQLPKKEDRMVYCSLTDFQKAVYQTVLETEDVALILTSSQPCTCGSGQKRRKCCYKTNSRGDTVRTLCLSYLTVLQKVANHVALLQAAS-TSKHQETVIKRICDRVFSRFPDFVQKSKDAAFETLSDPKYSGKMKVLQQLLNHFRKQRDKVLLFSFSTKLLDVLQQYCMASGLDYRRLDGSTKSEERLKIVKEFNSSQDVNICLVSTMAGGLGLNFVGANVVILFDPTWNPANDLQAVDRAYRIGQCRDVKVLRLISLGTVEEIMYLRQVYKQQLHCVVVGSENAKRYFEAVQGSKEHRGELFGVHNLFKLRSQGSCLTRDILE----------------------------REGQVEAGIMTATTWLKGEPSAQELETPRDPDCQEP-----------TDVCELYSDISDEESVGHSLGKTDKHKFSDTSRTPGFPAQLTLLQCGFSKLFEAKYKSDQDGDGNPVPSDGSSDEQPMCLSAEARQAARQKTWDSVCTSEHQKSDNIQTPDEKCVSDKSEKTLEQNVSSESDDETKDHRTAGHHCMGQGDTESEDSDVIFPTQYPTQRIPKNHIRFKLLLGESEDSEAENPVKVNHGDDRQNSG-RGNGPVPNLLCLENMTSKSVRKRKGTDDISDESDD-IDMFPKSRIRKQRATTSLKFKRKKENKRKLDNSPVTAKEANQVCAADGDRSSQVIEDFSSSDDNLSLSHLSFTKLSHRAETVKDKISLSPKLPGPDKKNNTFISRKPPSFLNEGVISQEQICNSMDKILDGVQEVAYIHSNQNVIGSSRAENHMSRWATRDVFELKQFSQLPANVAVCSSKTYKTQVKANIVSPTEKDQPPSDGGISSPLYVSHPVVQKKKDVYRTNHTTFIIGETPRGIRRKQFEEMASYYKLP-VKEFAEQVTRATSEERQKMLRDFYSLQHPEVKEFFVNSASELIKSVHKK-EERVRNKSKEKESLLKENPSNDSTLSCYDSTNKMSQVYNRKICEGKSVRSQNHVFHREDTFSSDAEINKSPVSFTEELHSERKDHTPKDTTTVFCPNSNSEALEAELGNSPGRQWDLTGACGSRNRPLFKLRNKRVENPGSENTPEDGLLGDTSILNDLFKSHGEGPTQLPKNVLSGPVAKAKQKPKDFWDILNEQNDDSLSKLTDLAVIETLCTKAPSTSASKRKDELEAS-LWKANEKFLWKTLSSDVDDESISNTERE-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T890-4", "uniprot_id": "ER6L2_HUMAN", "id": "Q5T890-4", "name": "DNA excision repair protein ERCC-6-like 2", "aln": "MQPGSAPPPGRMDPSAPQPRAETSGKDIWHPGERCLAPSPDNGKLCEASIKSITVDENGKSFAVVLYADFQERKIPLKQLQEVKFVKDCPRNLIFDDEDLEKPYFPNRKFPSSSVAFKLSDNGDSIPYTINRYLRDYQREGTRFLYGHYIHGGGCILGDDMGLGKTVQVISFLAAVLHKKGTREDIENNMPEFLLRSMKKEPLSSTAKKMFLIVAPLSVLYNWKDELDTWGYFRVTVLHGNRKDNELIRVKQRKCEIALTTYETLRLCLDELNSLEWSAVIVDEAHRIKNPKARVTEVMKALKCNVRIGLTGTILQNNMKELWCVMDWAVPGLLGSGTYFKKQFSDPVEHGQRHTATKRELATGRKAMQRLAKKMSGWFLRRTKTLIKDQLPKKEDRMVYCSLTDFQKAVYQTVLETEDVTLILQSSEPCTCRSGQKRRNCCYKTNSHGETVKTLYLSYLTVLQKVANHVALLQAAS-TSKQQETLIKRICDQVFSRFPDFVQKSKDAAFETLSDPKYSGKMKVLQQLLNHCRKNRDKVLLFSFSTKLLDVLQQYCMASGLDYRRLDGSTKSEERLKIVKEFNSTQDVNICLVSTMAGGLGLNFVGANVVVLFDPTWNPANDLQAIDRAYRIGQCRDVKVLRLISLGTVEEIMYLRQIYKQQLHCVVVGSENAKRYFEAVQGSKEHQGELFGIHNLFKFRSQGSCLTKDILE----------------------------REGQVEAGIMTATTWLKEGPPAHKLEMPRQPDCQECRGTEQAAEPLAKEACDLCSDFSDEEPVGATGIKTAKNKAPDSSKASSSPGQLTLLQCGFSKLLETKCKAVEDSDGNTASDDESSDEQPTCLSTEAKDAGCEKNQDSLGTSKHQKLDNILNPKEKHIFYKSEKILEQNISSKSDE--KKIKNTDKHCILQNVTESEDSDVICPTQYTTERFPDNSIRFKPPLEGSEDSETEHTVKTRNNDNSRNTDDKRNGIISKKLSPENTTLKSILKRKGTSDISDESDD-IEISSKSRVRKR--ASSLRFKRIKETKKELHNSPKTMNKTNQVYAANEDHNSQFIDDYSSSDESLSVSHFSFSKQSHRPRTIRDRTSFSSKLPSHNKKNSTFIPRKPMKCSNEKVVNQEQSYESMDKFLDGVQEVAYIHSNQNVIGSSKAENHMSRWAAHDVFELKQFSQLPANIAVCSSKTYKEKVDADTLPHTKKGQQPSEGSISLPLYISNPVNQKKKKVYHTNQTTFIIGETPKGIRRKQFEEMASYFNSSSVNEFAKHITNATSEERQKMLRDFYASQYPEVKEFFVDSVSQFNNSSFEKGEQRTRKKSDKRESLIKPRLSDSETLSFKDSTNKISQVCSLKTYKRKSVKFQNHISYREEVFFNDAETKKSPVSSTQEIDSGKNSQASEDTVTSRSLNSESETRERRLENTMKDQQDLTRTGISRKEPLLKLENKKIENPVLENTSVISLLGDTSILDDLFKSHGNSPTQLPKKVLSGPMEKAKQRPKDFWDILNEQNDESLSKLTDLAVIETLCEKAPLAAPFKRREEPATS-LWKSNEKFLWKKFSPSDTDENATNTQSTT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AV89-1", "uniprot_id": "A0A8M3AV89_DANRE", "id": "A0A8M3AV89-1", "name": "", "aln": "-----------MEMNEEK---DSS-------------------------------------------TKCQDARTPLPHFEDEK-----------------PLFHSNQTPPGPSEAFLLAGSDVKVPYTINRYLRDYQREGIKFIYQNYAKSRGCILGDDMGLGKTVQVIGFLAAVLQKTGTWKDVENNRPQFLLSQKPSER----VQKVFVIVAPLSVLYNWKDELDTWGHFRVVVVHGVRKDEELARVQRGRCEIALTTFETLRLCLDQFNSINWAAVIVDEAHKIKNHKSKITQAMKQMRCKVRIGLTGTILQNNLEELWCVMNWAVPRCLGSLGAFKNRFSDPIEKGQKHTVTKRALAEGRKAVQELAKKLSRWFLRRTKSLISDQLPKKDDRVVYCSLTDFQRTVYRAVLDSDDVTLMLQSSGKCPCSSGRPRKKCCYKLNADGVPVRHLYFSYLAILRKVANHVALLQSKDGTSKKQEKYVTTICEQVFRKFPDFTERCKQAAFEAMSDPMYSGKMKVMQKLLNHFIAKKDKVLLFSLSTKLLDVLESYCMAEGLEYHRLDGNTKSKDRVKIVKEFNSSRDVNLCLVSTLAGGLGLNFIGANVVVLFDPTWNPANDLQAIDRVYRIGQCRDVTVFRLISLGTVEEIIYLRQVYKQQLQSSVIGQENARRYFEAVQGTDGYAGELFGIRNLFRLQTDGTCLTHRILE----------------------------REGQLEVGIMTARTQAVDER------------MQEP---------------DPWSADAATERAG------------GSAGVCIKPAEVLDFSS------------------------GSEDEDPCCSKQRP--------------SETHSGEQMVASN-TCIGNTGLCNLLQKQMT---------------EIRQRDTDTEE-------------------------DSSSESQDED---------------------------ENCEKLTAIKTSKVKDLSSESEEELEGVSDGELQRRSHKDSTKDRKNHRRKR----------------VKFAERSEDEIEHFSWSDDE------GFLK---AVRCVKEKESDHRQSSRRENTTSGFKKSQS---------RDEGYTGTLDSLLGGLQQVGYTHSNQTVVGSSRAEDRLSRAAVREVFELHKHSQLPANQILDISETESS--DPILTDHVNGGQTPMTR---SGPHIEHPVTHTIKTSHRQNNLTVIVGETPSSMCRQQLEEMAQFFGFNSVRDFAEEILKSDSDQRLGRLRSFYSQKSPELMNIIKKTFPKPNIQPNPP-NAPPLSAARHKPTSKRAHPNSFVEVPTPEAEDRRKTSKKKKTSETEASEIDLHCS----TDLTKTEMKKSSTDISPSSSSGNIPQINCAPVEECIPNITSSSQPCTSRSACVSTDDCVASTSSQT---------------SSSSKITDLLGDTSILNDLFKTKKKVVDQPRDVKTSACTERAPKRGKDFWDILNEGNEESINKLTDLTEVEKICNSVSVSAKPKSNGETESSQLWKKNEKFLWKR-----------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: . : :: .. *: ** :::: * :..::. *. ** *: .. .:*************** :*:* :* .. *************:***.******:*.** :*:*** *:*** . .: .:*:*:*******************:***.*:** :**:** *::: :*******:*******:::**::*:*:******:*:* ::::*:.** ::*:********:****::******:**** *** **::****:*:**:**.*** ** ****::.****:* :******:**..*****:**:**.******::**::**:::**:*:* ** *.* **: *::**** *: * .*: * :***::*:**********: . ***:**. :. **::** :****.::.*:****::*** *******:::**** ::*******:********:.****.**:*:****.***::*:********::***:*****:********:*****:**************:**.*********.*:***********:****:*****:. *:*.***:********:. : *****::***:::::*:***: *** ****:*.***** * ** : * : * .* ..: . ..:: :.. *.**:* * . .. *: :. ::: .. . : .. * *: : : * *::*: *.:*: *. ** : * . ..*:*.**:: :: ....:::: * : : :. *: : ..: *:.:* **:. .* * . :: : . : . ::... * :. :* ::*.:*.*:*:*.* ****.*:***:**:::** *.::****::.****** : *:* . .. .: .* * ::.:** :. * :: *: *.*:**** .: *:*:****.:: *.:**:.: : *::: **.**: : **: ::: .: .: . : . : : : : . .. :. :: :: . . * : :: . : * . . :* :**... : . * . : . : *.: .: * . : *:. ..: .********:****:: : * . *. :* :: ********* *::*:.*****: :*.:* ... :: * . * :* *** ******* ", "identical_positions": 558, "similar_positions": 401, "identity": "34.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-280", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LK58-1", "uniprot_id": "A0ABK0LK58_RAT", "id": "A0ABK0LK58-1", "name": "", "aln": "MCFPRGMLLQSLLPACPGCRPAPRALLCQPLPGRPPCGLSRWRPALSADPLAPRPLLLPQDSSEVAALSALRPLRKEFVPFLLNFLREQSSRVLP-QGPSTPAKTPGASAALPARQGA--------PPRGGR-GARSQLFPATEPLS-----------------------------------TSAEAPLARRAGRR------------RGPGP--SRERG-------GRGSGGPEEGASSESPPWAGGRKPKGSGSPGSPRLSLSDPPNLSNLEEFPPVGTVPPGSAGRTKPSRRINPTPVSEERSLSKPKTCFTSPPISCVPSSQPSALDTSPWGLGLPPGCRSLQEEREMLRKARSKQLQQSPTPACPAPDSGSP---VPNRTGNLTAEP----ADPARVSSRQRLELVALIYSSCIAENLVPNLFLELFFVLQLLTARRMAATKDSDL--ESSQGALDSLETPLFRSIHDCVFFAVQVLEHQFQVLSYLDKGTLKLLAENERLLCFSP----ALQGRLRAAYEGSVAKVSLVIPPSAQAVSFQPETDNRANFSSDRAFHTFKKQRDVFYEVLREWEDHHEEPSWDFEKGLGSRIRAMMGQLSAACSHSHFVRLFQKQLLQMCQSPGGAGGSVLGEAPDVLNMLGADKLGRLRQLQERLIAPQSSGGPCPPPTFPGCQGFFRDFIMSASSFHFNQHLMDSLSLKIRELNGLRLPQHEPGDEDGE----SDVDWQGERRQFAVVLLSLRLLAKFLGFVAFLPYR---GHEPPPTRELQDSILALRSQVPPVLDIRALLQQGLWARRAVLTVPWLVEFLSFADHIVPLLDYYRSVFTLLLHLHRSLVLSKENEGEMCFLNKLLLLAVLGWLFQIPTVPEDLFFLEDGQVDAFEVDTTTSEHGLDSVPVVDQ-------QLLYTCCPYIGELRKLLASWVSGSSG-------RSGGFVRKITPTTTTSLGTLPLKTSQGLQAQLAEAFFHNQPPSLRRTVEFVAERIGSNCVKHIKATLVADLVHQAESLLQEQLVTRGQEGGDPAQLLEFLCSQLCPHGAQALTQGREFCQKKSPTALRALLPEETPAAVLSSAENIAVGLATEKACSWLSANIT--ALIRREVKAAVSRMLR------------AQGPEPTARVERRG--------CSRACEHHAPLPSHLISEIK-------DVLSLAAGPRDPEEGVSPEHLEQLLNQLGQSLKCRQFLCPTAEQHLAKCSVELASLLVADQIPILGPPTQHRLDRGHARRLLHMLLSLWKD----DFQGPVPLQLLLSPRNVGLLADTRPREWDLLLFLLRELVEKDLMGHLEIEACLVSLNEAQWPGDFSEELSTLFRLFLAEPHLLEPQLRACELMQPNRGTVLAQS------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CC12-1", "uniprot_id": "CDAN1_MOUSE", "id": "Q8CC12-1", "name": "Codanin-1", "aln": "MAAVLESLLREEVPVAAAVRWIARSTPSS------------------------------EDSSEVAALSALRPLRKEFVPFLLNFLREQSSRVLP-QGPSTPAKTPVASAALPARQGA--------PARGGR-GARSQLFPAAEPLS-----------------------------------AAAEAPLARRAGRR------------RGPGPGPSRERG-------GRGSGAAEEGASGESPPWAGGRKPKGSGSPGSPRLSLSDPPNLSNLEEFPPVGTVPPGSAGRTKPSRRINPTPVSEERSLSKPKTCFTSPPISCVPSSQPSTLDTSPWGLGLPPGCRSLQEEREMLRKARTKQLQQSPTPASPIPESGSP---VPSRTGNLTAEP----ADPARVSSRQRLELVALIYSSCIAENLVPNLFLELFFVLQLLTARRMVATKDSDL--ESSQGALDSLDTPLFRSIHDCVFFAVQVLEHQFQVLSYLDKGTLKLLAENERLLCFSP----ALQGRLRAAYEGSVAKVSLVIPPSAQAVSFQPETDNRANFSSDRAFHTFKKQRDVFYEVLREWEDHHEEPSWDFEKGLGSRIRAMMGQLSAACSHSHFVRLFQKQLLQMCQSPGGAGGSVLGEAPDVLNMLGADKLGRLRQLQERLIAPQSSGGPCPPPTFPGCQGFFRDFIMSASSFHFNQHLMDSLSLKIRELNGLRLPQHEPGDEDGE----SDMDWQGERRQFAVVLLSLRLLAKFLGFVAFLPYR---GHEPPPTRELQDSILALRSQVPPVLDIRALLQQGLWARRAVLTVPWLVEFLSFADHIVPLLDYYRSVFTLLLRLHRSLVLSKENEGEMCFLNKLLLLAVLGWLFQIPTVPEDLFFLEDGQVDAFEVTTTASEHGLDSVPVVDQ-------QLLYTCCPYIGELRKLLASWVSGSSG-------RSGGFVRKITPTTTSSLGALPLQTSQGLQAQLAEAFFHNQPPSLRRTVEFVAERIGSNCVKHIKATLVADLVHQAESLLQEQLVARGQEGGDPAQLLESLCSQLCPHGAQALTQGREFCQRKSPTAVRALLPEETPAAVLSSAENIAVGLATEKACSWLSANIT--ALIRREVKAAVSRMLR------------AQGPEPTARVERRG--------CSRACEHHAPLPSHLISEIKFHHCSLQDVLSLAAGPRDPEEGVSPEHLEQLLNQMGQSLRCRQFLCPTAEQHLAKCSVELASLLVADQIPILGPPTQHRLERGHARRLLHMLLSLWKD----DFQGPVPLQLLLSPRNVGLLADTRPREWDLLLFLLRELVEKDLMGHLEIEACLGRLNEAQWPGDFSEELSTLFRLFLAEPHLLEPQLRACELMQPNRGTVLAQS------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWY9-2", "uniprot_id": "CDAN1_HUMAN", "id": "Q8IWY9-2", "name": "Codanin-1", "aln": "MAAVLESLLREEVSVAAVVRWIARSTQGSE-----------------------------DNAGEAAALSSLRALRKEFVPFLLNFLREQSSRVLP-QGPPTPAKTPGASAALPGRPGG--------PPRGSR-GARSQLFPPTEAQS-----------------------------------TAAEAPLARRGGRR------------RGPGP--ARERG-------GRG---LEEGVSGESLPGAGGRRLRGSGSPSRPSLTLSDPPNLSNLEEFPPVGSVPPGPTG-TKPSRRINPTPVSEERSLSKPKTCFTSPPISCVPSSQPSALDTSPWGLGLPPGCRSLQEEREMLRKERSKQLQQSPTPTCPTPELGSP---LPSRTGSLTDEP----ADPARVSSRQRLELVALVYSSCIAENLVPNLFLELFFVFQLLTARRMVTAKDSDP--ELSPAVLDSLESPLFQSIHDCVFFAVQVLECHFQVLSNLDKGTLKLLAENERLLCFSP----ALQGRLRAAYEGSVAKVSLVMPPSTQAVSFQPETDNRANFSSDRAFHTFKKQRDVFYEVLREWEDHHEEPGWDFEKGLGSRIRAMMGQLSAACSHSHFVRLFQKQLLQMCQSPGGAGGTVLGEAPDVLSMLGADKLGRLWRLQERLMAPQSSGGPCPPPTFPGCQGFFRDFILSASSFQFNQHLMDSLSLKIQELNGLALPQHEPNDEDGE----SDVDWQGERKQFAVVLLSLRLLAKFLGFVAFLPYR---GPEPPPTGELQDSILALRSQVPPVLDVRTLLQRGLQARRAVLTVPWLVEFLSFADHVVPLLEYYRDIFTLLLRLHRSLVLSQESEGKMCFLNKLLLLAVLGWLFQIPTVPEDLFFLEEGPSYAFEVDTVAPEHGLDNAPVVDQ-------QLLYTCCPYIGELRKLLASWVSGSSG-------RSGGFMRKITPTTTTSLGAQPSQTSQGLQAQLAQAFFHNQPPSLRRTVEFVAERIGSNCVKHIKATLVADLVRQAESLLQEQLVTQGEEGGDPAQLLEILCSQLCPHGAQALALGREFCQRKSPGAVRALLPEETPAAVLSSAENIAVGLATEKACAWLSANIT--ALIRREVKAAVSRTLR------------AQGPEPAARGERRG--------CSRACEHHAPLPSHLISEIK-------DVLSLAVGPRDPDEGVSPEHLEQLLGQLGQTLRCRQFLCPPAEQHLAKCSVELASLLVADQIPILGPPAQYRLERGQARRLLHMLLSLWKE----DFQGPVPLQLLLSPRNVGLLADTRPREWDLLLFLLRELVEKGLMGRMEIEACLGSLHQAQWPGDFAEELATLSNLFLAEPHLPEPQLRACELVQPNRGTVLAQS------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UT82-1", "uniprot_id": "A0A8N7UT82_DANRE", "id": "A0A8N7UT82-1", "name": "", "aln": "MAALLESVLQSKVELSEAVLWLKGLHVCE------------------------------------SQNFPSRVTKEEFVPFLLNFLRDQSSQTLT-HGPATPAKTPSTSRSVRIQNSSERRVSKSTPVQGLRSASRVQLFSPAPFTSPGGGKNDQDTPFTGSLCLSGISALSSPSFSSVWSPVPRNSPSERRSAQRPSLGDFMTSPPETQPSPSAPPHRGRRRSAGFGGGTSSRQTGARGAVSEEGGGRRSRGGGRNDSVSPQTQVQLNFNNLEDFPPMAQPSP---IATKPSRRINPTPVSAERPNSKPKSCFTSTPLS-LPASPPKIPEST----GSP---HNLQEERELLKRERSKLAQQTSSPLKTNSEICTPTKTVHMQGSKVTPDSQLPCPDPDKVTQKSELDLLAGLYCACISENLVPCIFLEMFFVLQLLTSRGVSGSESAEQGISVCEDSPDVLEKAYLGNVHNCVYFSVRVLEKQFELVSHLDKCTLRLLSENERVGTFSS----SLKDCLAEAQDNCTAKVPPSPPLFVHSVPFQPATDNRSNFSSDKAFHTFKKQRDVFYGLLREWEDSHKEPGWDFEAALGNRVRMMVSQLTAAGSQSHFARLFQKQLVQMCKGPSVLASSSDAPDADLLGMLGADSLGRLKRLQQRLVQPQSLIGPCPPPSFPGHQEFFKGFLQTASSCQLNQHLKDGLCQQLLKLDEVSILGPDASPAQGEKTADGDMEQQDEKQRFSSVLLTARLLAKFLGFITFLPYQ---TSELP-SRDIQDAAVALRSKSFPVLDVCTVLRNSVHRRRTILTVPWMVEFLSMLDYIGPLLPCYRTALCLLLQIYKRMVLGRG--GELCYMNQLLMVAVLGWLFQIPVFPEDLFFSADLKEEMKELENKTSSQGLDTLPLVDQ-------QLLYTCCPYLGEFRKLLAAFVAGSTS-------KSGGLIRKITPTSAEPRGPSTTRSQQKLQVDLEQAFFHNQPPSLRRTVEFVAERVGSNCVKHIKATLVLELVRGGEKTLRDSL---GMEGVNTAKLNDCICAQLCDAGMQALERATRFCSENAPGAVRVLLPLETSPSVLTTAKSITTRLATEKACSWLSSNIT--TLLKREWKSAFERVMKSVPSPLSVDAEEAEGLSRSQQVQKSASGLSAGSTCVPGCAHKVPLGSEVMIEIK-------DVLSVAVGPRSDDEVFTVRQIESVLDRVGQTLGCRKRLSPVVEQMLLRCTVQLACKLVSGELPLVSS-----AEGNKRPDLLERFLVLWS------WTPAPPLHLLLTEPTLTAIFTATDRERTDYLFLIRQLIERGLLGEQEVGTNWAKLSALSWP---EESVEKFQQLSLATQFSMPQLPNHRDLLQVSQ-------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8T626-1", "uniprot_id": "DLT_DROME", "id": "Q8T626-1", "name": "Protein disks lost", "aln": "MTAELKASDTEMTKPEERHLLQLLAQLEKVP------------------HHQLEQKFVAYFKKVGKGDNQSNCTLEDFATYFLGALRQSTKRYYYSQNSETPVFPLTPIHQLKPPVADVVKEEEQQQLNESSILSRSSCSMSSTSNTT----------------------------------PAPQQPQGRRSTPG------------SGAQFCSTPNRS-------GGG------GAGGGHSICLGNFLVNTPIQSHQRSKKKITPQKQQQNQHASLGSGTGAGATPQSKPRRRVLPMTISKNVSAS---SSFGDTSSFSNENNFWRISQSSEIFDRSQEAALEMEARKFLLLK---KQEIKSEAPVNVSQQERTP------EDEVFPEEA----ISLEGVANANHLQLLSTIYSLLMDLNLVPNVLRELSFVVHLLNVRDFGQS-------PVKSYVPSALEG--LTQHKSCVYFAAKLLENQKKLLLQLDKRTLSVLLQNERLSLLPQGVVQELETHCQRRQDSTTPFAMDTSSSSQQNVYYHVENDSRDNFPSQNEFGAFKSQRDLFYKALKRWEVSHLNRGFNFPSELGPRIMDIYKKSEHPVNMTHLAKLFVNQLLISATETTESPEELG---------LKLDPLRHNKLAQRLVTSSSSVEG-----QFPRSQAFFRDFIAVCSSVAFLVHLKLELFVQLMRNNDSTFDLLQLTDDVAVE---EQSAQQGPYIVRVQTMANMLILAKFLGYVTVMPFSGTTQHGNPTPPYLCPQQLQLRNHFRPDFNLREILERSMRQGKLLITLPWLVQYLAMLDLVSLHLPDAVATLELLYGLYADIRMAKLQPAAVFIAR-----SCIGWLLDAQPQLVNGYYNYRAQEAGVGSISAIVDICLKDLSCHDKSHAPLLDELLPVACPFLQEFRVSITPSRQAKSGRFRYITTRLEQLQQNSSSISKDAIVASELSPAEQQQRKLVDAYLQSQNASTRRLIEFVTERTFKCVVKDAQQEILLPSKASADAKVNEIKSTMLEEVFQ--ELHEIFQDARENACQRWKEHVHQMLDRRIEHSLDGLLPSSTNAVLRSTYAHLIRVQAQTQLQQWLQSSVLQSTFYHGDLQELATKVCN----------------------------------CNRNKADAAAAGGGGSSELQLS-----PDIGFSLSEFLYQLQQWLHCLSLRPEYVGSQEDLAELLRKAQKAVLLPKMPTVFYHLIGSGLVHLLQLLITRKPNFLDKDIISASCSVWRSQQLMDSKASPGIFDGLISISFVQEMANSADSFRMLETILRSMLQSGAIRADHLNELFMPLFAENWSPKVWCMLSELLQQLSLSGKDSEAHYASGDSPEDEAKSHLFMEMLADLSRDLDNF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . . ::*..::*. **:.:.: :.. **. . . : . . :* . .: : . : * **. . . .*. * * *. . *. . : .: :. . . . :** **: * .:* : . * :.* ... . ::: .:: .: :* : * :: :* : :* . .. :. . *:. ..*:*:: :*. : **** :: *: **.:**. * . : . *: : . :.**:*:.::** : ::: *** ** :* :***: :. *: :. .. . . : * :: .*.* **.*:. * :**.***:** *:.** * : .::* ** *: : : . . :*:.:** :**: . . * * * : *. : ..* * ** * **:.*: .** : ** * :: . : : : . : *. .: . :******:::.:*: * . : : **.: * ::: :*...: : ::*:**:*::*:: * : * : ** :: : :.: . : . : :***:: : :: . . *. . *: :** ..**:: *:* ::. ..:. : : :: :. : . . . : * .* :*:::.* .* ** :***:** . **. : :: .: :.: * : :* : : : .: ... :: *** .* . : :: : * : **.:.: :: : : : : . * . .. . *:: :..: . : . :. :*. : * : * : *:.. : : :: :* . : * .. . ::*.::: . : .: * .*. : : . : : . ", "identical_positions": 169, "similar_positions": 354, "identity": "12.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JKA7-1", "uniprot_id": "HCN4_RAT", "id": "Q9JKA7-1", "name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDKLPPSMRKRLYSLPQQVGAKAWIMDEEEDGEEEGAGGLQDPSRRSIRLRPLPSPSPSVAAGCSESRGAALGAADSEGPGRSAGK------------------------------------------------SSTNGDCRRFRGSLASLGSRGGGSGGAGGGSSLGHLHDSAE-------------------ERRLIAAEGDASPGEDRTPPGLATEPERPGAAAQPA---------------------------------------------------ASPPP-QQPPQPASASCEQPSADTAIKVEGGAAASDQILPEAEV-----------------------------------------------------------------------RLGQSGFMQRQFGAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDENTTPWIVFNVVSDTFFLIDLVLNFRTGIVVED-NTEIILDPQRIKMKYLKSWFVVDFISSIPVDYIFLIVETRIDSEVYKT-------ARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPHDCWVSINGMVNNSWGKQYSYALFKAMSHMLCIGYGRQAPVGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKETKLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILLHKVQHDLNSGVFNYQENEIIQQIVRHDREMAHCAHRVQAAAS---ATPTP---TPVIWTPLIQAPLQAAAATTSVAIALTHHPRLPAAIFRPPPGPGLGNLG--AGQTPRHPRRLQSLIPSALGSASPASSPSQVDTPSSSSFHIQQLAGFSAPPGLSPLLPSSSSSPPPGACSSPP------------------------APTPSTST--AATTTGFGHFHKALGG----SLSSSDSPLLTPLQPGARSP-----QAAQPPPPLPGARGGLGLLEHFLPPPPSSRSPSSSPGQLGQPPGELSPGLAAGPP-STPETPPR-PERPSFMAGAS--GGASPVAFTPRGGLSPPGHSPGPPRT---FPSAPPRASGSHGSLLLPPASSPPPPQVPQRRGTPPLTPGRLTQDLKLISASQPALPQDGAQTLRRASPHSSGESMAAFSLYPRAGGGSG---SSGGLGPPGRPYGAIPGQHVTLPRKTSSGSLPPPLSLFGARAASSGGPPLT-AAPQREPGARSEPVRSKLPSNL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70507-1", "uniprot_id": "HCN4_MOUSE", "id": "O70507-1", "name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDKLPPSMRKRLYSLPQQVGAKAWIMDEEEDGEEEGAGGRQDPSRRSIRLRPLPSPSPSVAAGCSESRGAALGATESEGPGRSAGK------------------------------------------------SSTNGDCRRFRGSLASLGSRGGGSGGAGGGSSLGHLHDSAE-------------------ERRLIAAEGDASPGEDRTPPGLATEPERPATAAQPA---------------------------------------------------ASPPP-QQPPQPASASCEQPSADTAIKVEGGAAASDQILPEAEV-----------------------------------------------------------------------RLGQSGFMQRQFGAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDENTTPWIVFNVVSDTFFLIDLVLNFRTGIVVED-NTEIILDPQRIKMKYLKSWFVVDFISSIPVDYIFLIVETRIDSEVYKT-------ARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPHDCWVSINGMVNNSWGKQYSYALFKAMSHMLCIGYGRQAPVGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKETKLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILLHKVQHDLNSGVFNYQENEIIQQIVRHDREMAHCAHRVQAAAS---ATPTP---TPVIWTPLIQAPLQAAAATTSVAIALTHHPRLPAAIFRPPPGPGLGNLG--AGQTPRHPRRLQSLIPSALGSASPASSPSQVDTPSSSSFHIQQLAGFSAPPGLSPLLPSSSSSPPPGACGSPP------------------------APTPSTSTAAAASTTGFGHFHKALGG----SLSSSDSPLLTPLQPGARSP-----QAAQPPPPLPGARGGLGLLEHFLPPPPSSRSPSSSPGQLGQPPGELSLGLAAGPS-STPETPPR-PERPSFMAGAS--GGASPVAFTPRGGLSPPGHSPGPPRT---FPSAPPRASGSHGSLLLPPASSPPPPQVPQRRGTPPLTPGRLTQDLKLISASQPALPQDGAQTLRRASPHSSGESVAAFSLYPRAGGGSG---SSGGLGPPGRPYGAIPGQHVTLPRKTSSGSLPPPLSLFGARAASSGGPPLTTAAPQREPGARSEPVRSKLPSNL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y3Q4-1", "uniprot_id": "HCN4_HUMAN", "id": "Q9Y3Q4-1", "name": "Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDKLPPSMRKRLYSLPQQVGAKAWIMDEEEDAEEEGAGGRQDPSRRSIRLRPLPSPSPSAAAGGTESRSSALGAADSEGPARGAGK------------------------------------------------SSTNGDCRRFRGSLASLGSRGGGSGGTGSGSSHGHLHDSAE-------------------ERRLIA-EGDASPGEDRTPPGLAAEPERPGASAQPA---------------------------------------------------ASPPPPQQPPQPASASCEQPSVDTAIKVEGGAAAGDQILPEAEV-----------------------------------------------------------------------RLGQAGFMQRQFGAMLQPGVNKFSLRMFGSQKAVEREQERVKSAGFWIIHPYSDFRFYWDLTMLLLMVGNLIIIPVGITFFKDENTTPWIVFNVVSDTFFLIDLVLNFRTGIVVED-NTEIILDPQRIKMKYLKSWFMVDFISSIPVDYIFLIVETRIDSEVYKT-------ARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAVVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPDDCWVSINNMVNNSWGKQYSYALFKAMSHMLCIGYGRQAPVGMSDVWLTMLSMIVGATCYAMFIGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPPDTRQRIHDYYEHRYQGKMFDEESILGELSEPLREEIINFNCRKLVASMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTK-GNKETKLADGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVALDRLDRIGKKNSILLHKVQHDLNSGVFNYQENEIIQQIVQHDREMAHCAHRVQAAAS---ATPTP---TPVIWTPLIQAPLQAAAATTSVAIALTHHPRLPAAIFRPPPGSGLGNLG--AGQTPRHLKRLQSLIPSALGSASPASSPSQVDTPSSSSFHIQQLAGFSAPAGLSPLLPSSSSSPPPGACGSPS------------------------APTPSAGVA-ATTIAGFGHFHKALGG----SLSSSDSPLLTPLQPGARSP-----QAAQPSPAPPGARGGLGLPEHFLPPPPSSRSPSSSPGQLGQPPGELSLGLATGPL-STPETPPRQPEPPSLVAGAS--GGASPVGFTPRGGLSPPGHSPGPPRT---FPSAPPRASGSHGSLLLPPASSPPPPQVPQRRGTPPLTPGRLTQDLKLISASQPALPQDGAQTLRRASPHSSGESMAAFPLFPRAGGGSGGSGSSGGLGPPGRPYGAIPGQHVTLPRKTSSGSLPPPLSLFGARATSSGGPPLT-AGPQREPGARPEPVRSKLPSNL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TEJ3-1", "uniprot_id": "A0A8N7TEJ3_DANRE", "id": "A0A8N7TEJ3-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHRVHSSMRKRLYSLPHQFGHKGAMNRDGEDSD-------KDTRRKSVKMKHFPSPS---STGSSKGVCEAK-SGDAETDVGRPFR------------------------------------------------TNVNGDCRRFRGSLSSLTSRHAAPD-----------ADLAE-------------------QRRLIG---DASPEDDGPS-------EQPGPGESPG---------------------------------------------------AQGGRGDGAQQAPSE--EQS---TFVKLEG----IDQILPDDE------------------------------------------------------------------------RMYQAGFMHRQFGAMLQPGVNKFSLRMFGSEKAVEHEQERVKSAGFWIIHPYSDFRFYWDLIMLLLMVGNLIIIPVGITFFKDEHTPAWIVFNVVSDTFFLVDLVLNFRTGIVKED-STEIILDPQQIKVRYLRSWFAVDFLSSIPVDYIFLIVETRIDSDFYKT-------ARALRIVRFTKILSLLRLLRLSRLIRYIHQWEEIFHMT------------------------------YDLASAMVRIVNLIGMMLLLCHWDGCLQFLVPMLQDFPSDCWVAKNKMVNDTWGQQYSYALFKAMSHMLCIGYGMYPPVGMTDVWLTILSMIVGATCYAMFVGHATALIQSLDSSRRQYQEKYKQVEQYMSFHKLPADMRQRIHDYYEHRYQGKMFDEESILGELNEPLREEIISFNCRKLVATMPLFANADPNFVTSMLTKLRFEVFQPGDYIIREGTVGKKMYFIQHGVLTVLTK-GSKETKISDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDHFNEVLEEYPMMRRAFETVALDRLDRIGKRNSVLQHKVQRDLNSGVLNYQENEIIQQIVQHDRDMAHCAHLMQTPPPPPHPAPTPSSHTPVIWAPLIQAPLQAAAATTSVAIALTRHPHLPHTLFR-PPVPRLGSLKDQPGYFKRFPTALSGADTFGGSSSTSSQFSSCIETPILDTLRAERSSTSTPPPSSSSLPTTITTTVTTTTSSITESSHYHHRPIISHGSKDFSVAQLHSQPQLSQASFSSIAASLPGFFQQGAAGGEAVHLAVPPASTLTPLIAHSVSPILTQLHATHSNPQPTKPIQDLNKAGRTAPQSPVTESPVHSKSILEQVQSPTSVQSQHPQIGIQPDVLSQLAQEPSALASLAQYGSGNASPCSTPSAWSPTCQSPTAEKMRMSAHSQPSSISGSQTSLLTPQTLFPPPPQPRERGGSLVDLP---SQDLSTLSMS---LPIPGLAEKSRAVGR--GPQPPDLSHHRGSTSGYS---PLPSPPPLVNPFSSIPG-HVVLSRQTSKLSIT--------QTGSSGGSPAHGSSDRSTPGTPS--LHPKLPSNL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9N7-1", "uniprot_id": "A1Z9N7_DROME", "id": "A1Z9N7-1", "name": "", "aln": "MHVKHTQRRVSGPGAFGTFTNDQRASRDNLCPDNQQQQQQRHSHSHQHLVRQSLVSLSNGQPAASAAPDSVSLLRAGDDQQQHPQQPHLQQQQQQQQHLQQQQQRHRSSSSRLSTSGISKQNSSDSRSGLRILDSSHSPVSCGTQSVSSTGGQSALYDACHEYSRSLSAAAAEGAASLLKSHYSDQQLAQTEPDPEPDPERDRDRDRDRDRDRERERRHLTNLNLNLSSEYDYSGSDKQQLVNETYIFKCIANSPSFLRTNKIKEQSKKLRNLSLKTRTAKKKGQIISKSNAVSDNSLHPGDKYLNLYLVEKKHSLQPQVASTSSSINTTHPQASSAPASSSSTCTKAPQLPALSAVAARQQQLLLNGSLKGKGQSQSQGQSRQTLPGHRASVRSESGSGSSHTIPATGKSPPVPHSLAAKISSSASGSKNCNLLSASSNSCHKLNAHAQGSGAGSGSGSGSGSGPPGHSHYAAASPKSSVSSNGHLNKYCLTDLTRRKAEFNRQLSAPTDYTHHSSSNGSQQEGSSEANEGHEPVGESTITVASAGVSYPHPYSYPYHYAHHASSATAPANLKASLQLHSFGSHHPCPYPARPTSTSCTNSFNRRHIRRHKGKLGDRLLSGDSEESVRCSYCSVLNVNDNDLRISFENTCTDSLVTAFDDEALLICDQGTEMVHFDDVSLYGTPKEEPMPNIPIVSEKVSANFLKSQLQSWFQPTDNRLAMKLFGSRKALVKERIRQKTSGHWVIHPCSSFRFYWDLCMLLLLVANLIILPVAISFFNDDLSTRWIAFNCLSDTIFLIDIVVNFRTGIMQQDNAEQVILDPKLIAKHYLRTWFFLDLISSIPLDYIFLIFNQIMKLQDFSDSFQILHAGRALRILRLAKLLSLVRLLRLSRLVRYVSQWEEVYILQNLQKKSADRRGRMNRKDKDGLTKSNLILKFLNMASVFMRIFNLICMMLLIGHWSGCLQFLVPMLQGFPSNSWVSINELQESYWLEQYSWALFKAMSHMLCIGYGRFPPQSLTDMWLTMLSMISGATCYALFLGHATNLIQSLDSSRRQYREKVKQVEEYMAYRKLPRDMRQRITEYFEHRYQGKFFDEELILGELSEKLREDVINYNCRSLVASVPFFANADSNFVSDVVTKLKYEVFQPGDIIIKEGTIGTKMYFIQEGVVDIVMANGEVATSLSDGSYFGEICLLTNARRVASVRAETYCNLFSLSVDHFNCVLDQYPLMRKTMETVAAERLNKIGKNPNIMHQKDEQLSNP-----ESNTITAVVNALAAEADDCKDDDMDLKEN---------------------LLHGSESSIAEPVQTIREG---------LPRPRSGEFR----------ALFEGNTP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : :: :** *.. .. . ... :: :: :.: : :. . ::: . : ...*:::.. . : .. . *. ** : *. * . :: ... .. . :..* :. :: . : : * . .:.*:: *: : :** *::::::***.**: :*: * *::*.*:*** *.******* ****:*.****:**.*:**:*: :. **.** :***:**:*:*:******: :* ::****: * :**::** :*::****:******.: :. : :. .*****:*::*:***:********:**: ****:: : ::**..:**.*** ****: **.***********.** :.**: * : :. * :***:*************** .* .::*:***:**** ******:*:**** ************:** ****:**:::*** * **** :*:*******:**** *****.* ***::*.:***.***::*:*****.***:.::***::******* **:***:*.******.**: :: *. *.::************..**.*****:***.*:*****:** **::**:**:::**** :**::***. .:: :* :: *. :.* * : : .* . *:.: :: : .: :. * . *.: :.. . ", "identical_positions": 326, "similar_positions": 241, "identity": "18.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-31", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9P2N5-1", "uniprot_id": "RBM27_HUMAN", "id": "Q9P2N5-1", "name": "RNA-binding protein 27", "aln": "MLIEDVDALKSWLAKLLEPICDADPSALANYVVALVKKDKPEKELKAFCADQLDVFLQKETSGFVDKLFESLYTKNYLPLLEPVKPEPKPLVQEKEEIKEEVFQEPAEEERDGRKKKYPSPQKTRSESSERRTRE-KKREDGKWRDYDRYYERNELYREKYDWRRGRSKSRSKSRGLSRSRSRSRGRSKDRDPN-RNVEHRERSKFKSERNDLES---------------SYVPVSAPPPNSSEQY-SSGAQSIPSTVTVIAPAHHSENTTESWSNYYNNHSSSNSFGRNLPPKRRCRDYDERGFCVLGDLCQFDHGNDPLVVDEVALPSMIPFPPPPPGLPPPPPPGMLMPPMPGPGPGPGPGPGPGPGPGPGPGHSMRLPVPQGHGQPPPSVVLPIPRPPITQSSLINSRDQPGTSAVPNLASVGTRLPPPLPQNLLYTVSERQPMYSREHGAAASERLQLGTPPPLLAARLVPPRNLMGSSIGYHTSVSSPTPLVPDTYEPDGYNPEAPSITSSGRSQYRQFFSRTQTQRPNLIGLTSGDMDVNPRAANIVIQTEPPVPVSINSNITRVVLEPDSRKRAMSGLEGPLTKKPWLGKQGNNNQNKPGFLRKNQYTNTKLEVKKIPQELNNITKLNEHFSKFGTIVNIQVAFKGDPEAALIQYLTNEEARKAISSTEAVLNNRFIRVLWHRENNEQPTLQSSAQLLLQQQQTLSHLSQQHHHLPQHLHQQQVLVAQSAPSTVHGGIQKMMSKPQTSGAYVLNKVPVKHRLGHAGGNQSDASHLLNQSGG-AGEDCQIFSTPGHPKMIYSSSNLKTPSK-LCSGSKSHDVQEVLKKKQEAMKLQQDMRKKRQEVLEKQIECQKMLISKLEKNKNMKPEERANIMKTLKELGEKISQLKDELK-TSSAVSTPSKVKTKTEAQKELLDTELDLHKRLSSGEDTTELRKKLSQLQVEAARLGILPVGRGK--TMSSQGRGRGRGRGGRGRGSLNHMVVDHRPKALTVGGFIEEEKEDLLQHFS----------------------------TANQGPKFKDRRLQISWHKPKVPSISTETEEEEVKEEE--------TETSDLFLP----DDDDEDEDEYESRSWRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SFM8-1", "uniprot_id": "RBM27_MOUSE", "id": "Q5SFM8-1", "name": "RNA-binding protein 27", "aln": "MLIEDVDALKSWLAKLLEPICDADPSALANYVVALVKKDKPEKELKAFCADQLDVFLQKETSGFVDKLFESLYTKNYLPPLEPVKPEPKPLVQEKEEIKEEVFQEPAEEERDTRKKKYPSPQKSRSESSERRTRE-KKREDGKWRDYERYYERNELYREKYDWRRGRSKSRSKSRGLSRSRSRSRGRSKDRDPN-RNVEHRERSKFKSERNDLES---------------SYVPVSAPPPSSSEQY-SSGAQSIPSTVTVIAPAHHSENTTESWSNYYNNHSSSNSFGRNPPPKRRCRDYDERGFCVLGDLCQFDHGNDPLVVDEVALPSMIPFPPPPPGLPPPPPPGMLMPPMPGPGPGPGPGPGPGPGPGPGPGHSMRLPVPQGHGQPPPSVVLPIPRPPISQSSLINSRDQPGTSAVPNLAPVGARLPPPLPQNLLYTVSERQPMYSREHGAAASERLQLGTPPPLLAARLVPPRNLMGSSIGYHTSVSSPTPLVPDTYEPDGYNPEAPSITSSGRSQYRQFFSRAQTQRPNLIGLTSGDMDANPRAANIVIQTEPPVPVSVNSNVTRVVLEPESRKRAISGLEGPLTKKPWLGKQGNNNQSKPGFLRKNHYTNTKLEVKKIPQELNNITKLNEHFSKFGTIVNIQVAFKGDPEAALIQYLTNEEARKAISSTEAVLNNRFIRVLWHRENNEQPALQSSAQILLQQQHTLSHLSQQHHSLPQHLHPQQVMVTQSSPSSVHGGIQKMMGKPQTSGAYVLNKVPVKHRLGHASTNQSDTSHLLNQTGGSSGEDCPVFSTPGHPKTIYSSSNLKAPSK-LCSGSKSHDVQEVLKKKQEAMKLQQDMRKKKQEMLEKQIECQKMLISKLEKNKNMKPEERANIMKTLKELGEKISQLKDELK-TSSTVSTPSKVKTKTEAQKELLDTELDLHKRLSSGEDTTELRKKLSQLQVEAARLGILPVGRGK--TISSQGRGRGRGRG-RGRGSLNHMVVDHRPKALPGGGFIEEEKDELLQHFS----------------------------ATNQASKFKDRRLQISWHKPKVPSISTETEEEEVKEEE--------TETSDLFLH----DDDDEDEDEYESRSWRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B6T7-1", "uniprot_id": "A0ACD6B6T7_DANRE", "id": "A0ACD6B6T7-1", "name": "", "aln": "MIIDNVDALKSWLAKLLEPICDADPSALANYVVALVKKDKPEKELRALCADQLDVFLQKETTGFVDKLFECLTTKNYLGP-PAVKEEVKIPVQKLEEKEETAHVE---DDRENRRRR--SPLRNRSDFNESRARDDRRRDDRKRREVDRHLKSGESYRDRHERRGGSSRGRSYSRSRSRSRSGSRGKSREREHNQRRAEHR--SKFEQERKEAEPYNPSSAHMSNPHHQQTHPPPLLPLPLPQHQFPSSGSPAVPKAATVVAPVHLPDSTTESWSAYFTNHSDGKTFNKSNTLKHRCRDYDEKGFCIRGDLCPFDHGNDPLIVDDVTLPTMIPFPPPP------ALPRMPMPPMTEPPPG------------------MPMPLPP-HGQPPPPGIYPMP---AGGPPAILSRPTGG------LLPTGPPLIP--------ATGIDTPPHSRTSTSSPLALPGVGPPP-------NPPPPLPTSSSSSSASLHPQYTLSEYNYDPEAYNPESPGLTGPGRAQYRHFIPRIQTQRPNLIGLTSGDG-LNSRAANIVIQTEPSVTSVSNS-EMRFNSEQENRKRCLPSTDGPQVKKPWMDKPNFNNQHKPTFPKKHYYVNTKLEVRRIPRELNNITKLNEHFSKFGTIVNIQVVFGGDPEAALIQYTANDEARRAISSTEAVLNNRFIRVYWHREPTANTQEQGPSQ-------------------------------STNPGQQHPPTHKVINKQHPAASYVLNKTIPKH---HAATGTAGITGSTEPTSPSQEPSVGLTPPSSLVKGPFSRTVLKAASKSLGKTGKALEAQEALKKKQEALKLQQDMRKKKQEMLEKQIECQKVLINRLEKNRGMKPEERANIMKTLKELTEKISQLKNEISPTAQATANTTQSKSKTDAQKELLDAELDFHKKLTSGEDTTDLKRRLGQLQVEATRLGLIPAGRGKPSLAPTRGRGRGRGRNLRGRGGANHMVVDHRPRALSIIGFTQEEKEELMPHFVKFGEIEELREHDASSVVMTFKTRSDAENAANQGAKFKGRILQISWYKPKTPSVSTEPEEEESKEEVNAAGIHVMTEPVSPFLLPEEEEEDDDEDDEYESRSWRR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*::****************************************:*:*************:********.* ***** .** * * **: ** :* .. * ::*: *::: ** :.**: .* *:*: ::*:* * *: :*: : .* **:::: * * *:.** **. ***** ***:*::*: * *..*** ***:.**:: *. :: * * * ...*: ***: ::*.:.**:**.* .:.****** *:.***..::*.:. . *:*******:***: **** ********:**:*:**:******** . * * ****. * ** * :*:* ******. : *:* .. * ** * * ..*. * * :.. * :** ::. :*.** ** * ** . :*: . .* .*:*:.****:*.:*..**:***:*:.* ************** *.***********.*. ** *. * :.***.:.. :** .****:.* . *** ** * :*: *.******::**:***********************.* ********** :*:***:**************** **** . :. *..:* .: *. * :*::.* :.:.:*****. ** **. . :. : : :. . : .... * :* : **:.** * . .*: :.**.*******:*********:**:*********:**.:****:.**************** *******:*:. *:.:.:..:: *:**:*******:***:**:*:******:*:::*.******:***::*.**** .::********. ****. *********:**. ** :***::*: ** ::**..***.* *****:***.**:***.**** *** **. . ** ::**:::**********", "identical_positions": 550, "similar_positions": 253, "identity": "48.98%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-32", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q16873-1", "uniprot_id": "LTC4S_HUMAN", "id": "Q16873-1", "name": "Leukotriene C4 synthase", "aln": "MKDEVALLAAVTLLGVLLQAYFSLQVISARRAFRVSPPLTTGPPEFERVYRAQVNCSEYFPLFLATLWVAGIFFHEGAAALCGLVYLFARLRYFQGYARSAQLRLAPLYASARALWLLVALAALGLLAHFLPAALRAALLGRLRTLLPWA---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q60860-1", "uniprot_id": "LTC4S_MOUSE", "id": "Q60860-1", "name": "Leukotriene C4 synthase", "aln": "MKDEVALLATVTLVGVLLQAYFSLQVISARRAFHVSPPLTSGPPEFERVFRAQVNCSEYFPLFLATLWVAGIFFHEGAAALCGLFYLFARLRYFQGYARSAQLRLTPLYASARALWLLVAMAALGLLVHFLPGTLRTALFRWLQMLLPMA---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F8E5-1", "uniprot_id": "E7F8E5_DANRE", "id": "E7F8E5-1", "name": "Leukotriene C4 synthase", "aln": "MLDQIVLLAAVTVLGLLEQAYFSLQVIYARRKYAVSPPATSGPPEFERIFRAQANCSEYFPIFVFSLWLAGVFFSQVLAVIFGLLYLYGRFRYFHGYAESSKGRLEPLYFSAKMQWVLIALAGLGIICTLTQVYLGLDLLHTFSHVLGLTEQT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *::.***:**::*:* ********* *** : **** *:*******::***.*******:*: :**:**:** : *.: **.**:.*:***:***.*:: ** *** **: *:*:*:*.**:: : * *: : :* : ", "identical_positions": 79, "similar_positions": 40, "identity": "51.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-37", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BXN7-1", "uniprot_id": "PPM1K_MOUSE", "id": "Q8BXN7-1", "name": "Protein phosphatase Mn(2+)-dependent 1K", "aln": "-MLSAAFITLLRSGGNQVKKRVLLSSILLQDHRQATPACYFSTSEAR--CSRFDPDGSGQPATWDNFG-IWDNRIDEPILLPPSIKYGKPIPKISLENVGCASLIGK--RKENEDRFGFAQLTEEVLYFAVYDGHGGPAAADFCHTHMEKCVMD-------------------LLPREKDLETVLTLAFLEIDKAFASYAHLSADAS-LLTSGTTATVALLRDG-------------VELVVASVGDSRALLCRK-GKPMKLTTDHTPERKDEKERIKKFGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKASGVIAEPETTRIKL---------------YHADDSFLVLTTDGINFMVNSQEICDFVNQCHD----PKEAAHSVTEQAIQYG------TEDNSTAVVVPFGAWGKYKNSEITFSFSRSFASSGRWA-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6K136-1", "uniprot_id": "PPM1K_RAT", "id": "A6K136-1", "name": "Protein phosphatase Mn(2+)-dependent 1K", "aln": "-MLSTAFITLVRSGRNQVKKRVLLSSILLQDHRQMTPACYCSISEPR--CSRFDPDGSGQPATWDNFG-IWDNRIDEPILLPPSIKYGKPIPKISLENVGCASLIGK--RKENEDRFGFAQLTEEVLYFAVYDGHGGPAAADFCHTHMEKCVTD-------------------LLPREKDLETVLTLAFLEIDKAFSSYAHLSADAS-LLTSGTTATVALLRDG-------------VELVVASVGDSRALLCRK-GKPMKLTTDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKASGVIAEPETTRIKL---------------YHADDSFLVLTTDGINFMVNSQEICDFVNQCHD----PKEAAHAVTEQAIQYG------TEDNSTAVVVPFGAWGKYKNSEITFSFSRSFASSGRWA-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N3J5-1", "uniprot_id": "PPM1K_HUMAN", "id": "Q8N3J5-1", "name": "Protein phosphatase Mn(2+)-dependent 1K", "aln": "-MSTAALITLVRSGGNQVRRRVLLSSRLLQDDRRVTPTCHSSTSEPR--CSRFDPDGSGSPATWDNFG-IWDNRIDEPILLPPSIKYGKPIPKISLENVGCASQIGK--RKENEDRFDFAQLTDEVLYFAVYDGHGGPAAADFCHTHMEKCIMD-------------------LLPKEKNLETLLTLAFLEIDKAFSSHARLSADAT-LLTSGTTATVALLRDG-------------IELVVASVGDSRAILCRK-GKPMKLTIDHTPERKDEKERIKKCGGFVAWNSLGQPHVNGRLAMTRSIGDLDLKTSGVIAEPETKRIKL---------------HHADDSFLVLTTDGINFMVNSQEICDFVNQCHD----PNEAAHAVTEQAIQYG------TEDNSTAVVVPFGAWGKYKNSEINFSFSRSFASSGRWA-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5Q7-1", "uniprot_id": "A0ACD6B5Q7_DANRE", "id": "A0ACD6B5Q7-1", "name": "protein-serine/threonine phosphatase", "aln": "--MSVSAVCFSR---------------LLRCARCVHPARCVRVPGVRWHTTRLDMDGSGRPATWDSFG-IWDNRIEEPILLPPSIRYGTPIPHISLSRVGCATLIGR--RRENEDRFQVSELTQNVLYFALFDGHGGAHAADYCHKHMEQNIRD-------------------CLEMETDLQTVLSKAFLEVDAALEEKLQIYGNAS-LMMVGTTATVALLRDG-------------IELVVGSVGDSRALLCRK-GKSRKLTDDHTPERKDEKHRIRQSGGFVTWNSVGQANVNGRLAMTRSIGDFDLKKSGVIAEPEITRTLL---------------QHAHDSFLVLTTDGVNFIMSNQEICDIINLCHD----PTEAANVIAEQALQYG------SEDNSTVIVVPFGAWGKHQNTDYTHDMSRNFASIGRWS-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25646-1", "uniprot_id": "PDP2_YEAST", "id": "P25646-1", "name": "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial", "aln": "MRLGNAYAYCKPSQNVGLKLDLLRGLPGYVGHATSRINRLENQDNYSIKMMRSWPNAYGSALNCSVFDGHGEKGAQLSQLLADKLCSSLDFPEPSWDKQDLKKLVQEYARRFPEGNYWKHKLSTFEKFYNKFIKNCNSKQELLLMKEGDSAILGQNGGRMIFDKMGNIIDKIALLTELDRLRLFYGFARFDLDQCCGLGTAAGSTASSIFLYPYDDPNAPIDEGKDDDSWIISHSGLLKLIVTQVGDSKIILCDQDGIAHALTTTHHINSSRERHRLSIDPSRLDPDAFGETRFLNNFANTRSFGDVAGKPYGISSEPDIFSFLVGNTLHLPRSERSKLPFNGDECFLALVTDGITNKLADQEVVDLITSTVNSWGLKKATPQFVAEETIKFIQAIATKHSDNATCVVVRLSNWGNWPNVDRTGPQRETKLMNAQSNETKLN", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :. * . . . *. :: : . **. .: . :*. * .. . . : . *: *..: :*: :: : : .. .. :. : . * *. . * :::* . . *: :: . * : :* ::*:* .****: :** : * . ** * : . *:.*: . : ::.*:... ..:* ***:**. * *: :**: : :..:.**.*.***:. : .**: *::. : . :.: ::*::::: .**:* :** :. **: * : . .. .: ", "identical_positions": 60, "similar_positions": 124, "identity": "13.57%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-38", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC05-1", "uniprot_id": "B1WC05_RAT", "id": "B1WC05-1", "name": "Box C/D snoRNA protein 1", "aln": "MEFAAEKEGTPGGGPQRVAEGARPRPAAGGEGAGDLGGSPEADDGEERNGLTGIKTTED--------AEEIKMDLAVVKQEVVDWSDLDGDISDSHWVKQEVEGGPEVKAE-KDVLEVKQEADSSLVVKEEEVDEPEVKEEKVKVKEEVTDWEEAKEE--DLNVKQ-ELFVGQNVKEEQVMDRVPVKEEDCFKREVTEDTKVKEEPQMNPRVGCKRKLAMSRCETCGTEEAKYRCPRCMRYSCSLPCVKRHKAELMCSG-VRDKTAYVSLQRFTEMN---------LLSDYRFLEDVARTADRVSRDIFLTRPKRK-----KYLLFLKN---------------RARKQGVYLRLLPSGFSKRRENSTVFDHRNQQFCWHVKLQFPQSQAEYVEKRVPDDKTINEILKPYIDPEKSDPVIRQRLKAYTQS---------QTGVQILMRVENMQQNLIRYYELDPSKSLVNNLRNKVIIEYPTLHVVLKGCSNDMQLLHQVKSESAQKLGNGD---------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UFB2-1", "uniprot_id": "BCD1_MOUSE", "id": "Q3UFB2-1", "name": "Box C/D snoRNA protein 1", "aln": "MESAAEKEGTPGGGSQRVAEGARPRPAAGGEGARDLDGSPEAGDGEERNGLAGTKTTED--------AEEIKMDLAVVKQEVVDWSDLDSGVADSQWVKQEVEGGPEVKDE-KGVLEVKQEADSSLVVKEEEVDEPEVKEEKVKVKEEVTDWEEVKEE--DLTIKQ-ELFVGQNVKEEQVMDAAPIKEEGSLKSEAMEDAKVKEEPQMNPRVGSKRKLALSRCETCGTEEAKYRCPRCMRFSCSLPCVKKHKADLTCSG-VRDKTAYVSLQQFTEMN---------LLSDYRFLEDVARTADKVSRDTFLKRPKRK-----KYLFFMKN---------------RARKQGIYLRLLPNGFSKRKENSTVFDHRKQQFCWHVKLQFPQSQAEYIEKRVPDDKTINEILKPYIDPEESDPVIRQRLKAYAQS---------QTGVQILMRVENMQQNMIRYHELDPYKSLSDNLKDKVIIEYPTLHVVLRGSSNDKQLL-QVKSESAQKLGNGN---------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NWK9-1", "uniprot_id": "BCD1_HUMAN", "id": "Q9NWK9-1", "name": "Box C/D snoRNA protein 1", "aln": "MEFAAENEGKSGGGLHSVAEGVRLSPEPGREGVRDLAGAEEFGGGEEGTGLTGIKEIGDGEEGSGQRPEEIPMDLTVVKQEIIDWPGTEGRLAG-QWVEQEVEDRPEVKDENAGVLEVKQETDSSLVVKEAKVGEPEVKEE--KVKEEVMDWSEVKEEKDNLEIKQEEKFVGQCIKEELMHGECVKEEKDFLKKEIVDDTKVKEEPPINHPVGCKRKLAMSRCETCGTEEAKYRCPRCMRYSCSLPCVKKHKAELTCNG-VRDKTAYISIQQFTEMN---------LLSDYRFLEDVARTADHISRDAFLKRPISN-----KYMYFMKN---------------RARRQGINLKLLPNGFTKRKENSTFFDKKKQQFCWHVKLQFPQSQAEYIEKRVPDDKTINEILKPYIDPEKSDPVIRQRLKAYIRS---------QTGVQILMKIEYMQQNLVRYYELDPYKSLLDNLRNKVIIEYPTLHVVLKGSNNDMKVLHQVKSESTKNVGNEN---------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TIB7-1", "uniprot_id": "A0AB32TIB7_DANRE", "id": "A0AB32TIB7-1", "name": "Box C/D snoRNA protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKMNLPDVDNNTADEERRAVKRKMAMSRCDVCDCEEAKYRCPSCKKHTCSLVCVKRHKSVSGCSG-VRDQTAFVSLSDFREIH---------MLSDYRFLEDSARLRQQSSRDTVMTSGRQHP----KQGQWMIR---------------KAKAVKVTLKLLPKVFSKHRENTTVFIHRERRFHWHLNIHFPQSEAVYSERR-PDNTPLEQILHGYIHPSEADPVRRQKLKLYVSS---------QQNIRVFLKAELEQLNSLRYHELELNKTLQENLMYKTIIEYPELFVVLDQHSQQYHTPEPDAPDEGTASASSSPSETPAKKKPRVSEDEDLEDGELRSEDDEENQHHTQNKLAEDAERTAGPPEEEHKPSGESERAHDDDDDDDEGQTDRPRPS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38772-1", "uniprot_id": "BCD1_YEAST", "id": "P38772-1", "name": "Box C/D snoRNA protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAVLCGVCGIKEFKYKCPRCLVQTCSLECSKKHKTRDNCSGQTHDPKEYISSEALKQADDDKHERNAYVQRDYNYLTQLKRMVHVQKMDARMKNKRVLGPVGGHNSNFKKRRYDIDEDDRDSTECQRIIRRGVNCLMLPKGMQRSSQNRSKWDKTMDLFVWSVEWILCPMQEKGEKKELFKHVSHRIKETDFLVQGMGKNVFQKCCEFYRLAGTSSCIEGEDGSETKEERTQILQKSGLKFYTKTFPYNTTHIMDSKKLVELAIHEKCIGELLKNTTVIEFPTIFVAMTEADLPEGYEVLHQEPRPLEHTSTLNKFIDNAREEEDAE-------EDSQPTEEPVQKETQDASDSDSDSDDDYNPGLSMDFLTA--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .*. :* **:** * :*** * *:**: *.* .:* . ::* . : : . : **.:* : * . . * :. : : . : : :**. : : :* : : : * * :: : : ::. .. . . :: .. * :: : * : : . : : * . :::: . . : * ::* . : :: .. ", "identical_positions": 34, "similar_positions": 77, "identity": "5.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P05107-1", "uniprot_id": "ITB2_HUMAN", "id": "P05107-1", "name": "Integrin beta-2", "aln": "MLGLRP-PLLALVGLLSLGCVLS--QECTKFKVSSCRECIESGPGCTWCQKLNFTGPGDPDSIRCDTRPQLLMRGCAADDIMDPT----SLAETQEDHNGGQKQLSPQKVTLYLRPGQAAAFNVTFRRAKGYPIDLYYLMDLSYSMLDDLRNVKKLGGDLLRALNEITESGRIGFGSFVDKTVLPFVNTHPDKLRNPCPNKEKECQPPFAFRHVLKLTNNSNQFQTEVGKQLISGNLDAPEGGLDAMMQVAACPEEIGWRNVTRLLVFATDDGFHFAGDGKLGAILTPNDGRCHLEDNLYKRSNEFDYPSVGQLAHKLAENNIQPIFAVTSRMVKTYEKLTEIIPKSAVGELSEDSSNVVHLIKNAYNKLSSRVFLDHNALPDTLKVTYDSFCSNGVTHRNQPRGDCDGVQINVPITFQVKVTATECIQEQSFVIRALGFTDIVTVQVLPQCECRCRDQSRDRSLCHGKGFLECGICRCDTGYIGKNCECQTQGRSSQELEGSCRKDNNSIICSGLGDCVCGQCLCHTSDVPGKLIYGQYCECDTINCERYNGQVCGGPGRGLCFCGKCRCHPGFEGSACQCERTTEGCLNPRRVECSGRGRCRCNVCECHSGYQLPLCQECPGCPSPCG-KYISCAECLKFEKGPFGKNCSAACPGLQLSNN-PVKGRTCKERDSEGCWVAYTLEQQDGMDRYLIYVDESRECVAGPNIAAIVGGTVAGIVLIGILLLVIWKALIHLSDLREYRRFEKEKLKSQWNNDNPLFKSATTTVMNPKFAES-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11835-1", "uniprot_id": "ITB2_MOUSE", "id": "P11835-1", "name": "Integrin beta-2", "aln": "MLGLRPSLLLALAGLFFLGSAVS--QECTKYKVSSCRDCIQSGPGCSWCQKLNFTGPGEPDSLRCDTRAQLLLKGCPADDIMDPR----SIANPEFDQRGQRKQLSPQKVTLYLRPGQAAAFNVTFRRAKGYPIDLYYLMDLSYSMLDDLNNVKKLGGDLLQALNEITESGRIGFGSFVDKTVLPFVNTHPEKLRNPCPNKEKACQPPFAFRHVLKLTDNSNQFQTEVGKQLISGNLDAPEGGLDAIMQVAACPEEIGWRNVTRLLVFATDDGFHFAGDGKLGAILTPNDGRCHLEDNMYKRSNEFDYPSVGQLAHKLSESNIQPIFAVTKKMVKTYEKLTEIIPKSAVGELSDDSSNVVQLIKNAYYKLSSRVFLDHSTLPDTLKVTYDSFCSNGASSIGKSRGDCDGVQINNPVTFQVKVMASECIQEQSFVIRALGFTDTVTVQVRPQCECQCRDQSREQSLCGGKGVMECGICRCESGYIGKNCECQTQGRSSQELERNCRKDNSSIVCSGLGDCICGQCVCHTSDVPNKEIFGQYCECDNVNCERYNSQVCGGSDRGSCNCGKCSCKPGYEGSACQCQRSTTGCLNARLVECSGRGHCQCNRCICDEGYQPPMCEDCPSCGSHCRDNHTSCAECLKFDKGPFEKNCSVQCAGMTLQTI-PLKKKPCKERDSEGCWITYTLQQKDGRNIYNIHVEDSLECVKGPNVAAIVGGTVVGVVLIGVLLLVIWKALTHLTDLREYRRFEKEKLKSQWNNDNPLFKSATTTVMNPKFAES-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FCN5-1", "uniprot_id": "E7FCN5_DANRE", "id": "E7FCN5-1", "name": "Integrin beta", "aln": "---MHQSVCLKSLLLLLVGTQVYTQEQCLKASVNTCGDCIKSGPGCAWCKELNFTKTGEQEAARCDTVKLLLDRGCSKENIINPQNIFQNVVNKALVAGKDPVQIQPQEIQLNLRPGMPQTFQLRFKRAEGYPVDLYYLMDLSYSMKDDLANVKNLGNDILEKLNRITGNARIGFGSFVDKTLLPYTDTNEAKLKHPCSDKNEPCQPAFGFQHVLPLTANGNDFKELVKQQHISGNLDPPEGSLDAIMQAAVCLKEIGWGNSTRLLVLATDDGFHMAGDGKLAAILEPNKETCQLDKNKYSKSNIWDYPSVGQVARKLEEQNIQPIFAVTKKMETVYTELSKLIPKSAVGVLSEDSNNVVNLIVEAYNNLTSEVIMAHDALPNFISVKYSSKCTGGKTFSDN--GKCDNVNIGLEVIFDVTVTVDRCINDQSFSIGPLGFNEKLKVNVQTLCECNCGDPPGVHPHCKGQGKVVCGSCKCNDGFIGQLCECTIGKKDEASFKAQCRKDN-GTECEGKGDCVCGRCQCHLTEG-NGHFYGEHCECDDEHCEKFDNKQCAG--HGKCKCGKCECDDGYEGTACHCAKSDNECKIDS-HVCYNRGKCVCNQCECERGYKGPYCKTCPTCQRPCQ-QSGSCVECFAFQSGPFEKNCSLACKHLTIKIVDKLVKSDCRVKDKEGCWMAFTMTEELGFDLYSVSVLKDRECPEGPNIIAIVGGSLAGVALIGLLMLLIIKGVLYASDLREWRRFEKDRKHEKTSGTNPLFQNATTTVQNPTFSGDS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * *: :* : ::* * .*.:* :**:*****:**::**** .*: :: **** ** :**. ::*::* .:.: *:.**:: * **** . :*:: *:**:***:************ *** ***:**.*:*. **.** ..***********:**:.:*: **::**.:*:: ***.*.*:*** ** *.*:*: * :* ******.***.***:**.*.* :**** * *****:*******:******.*** **. *:*:.* *.:** :*******:*:** *.*********.:* ..* :*:::******* **:**.***:** :** :*:*.*:: *.:**: :.*.*.* *:.* : .: *.**.*:*. : *:*.* . .**::*** * .***.: :.*:* . ***.* * . :. * *:* : ** *:*: *:**: *** :.. .:: .***** . *.* ***:**:* ** :: . ::*::**** :**:::.: *.* :* * **** *. *:**:**:* :: * * .**:* ** * *. **: * *: ** * * : **.**: *:.*** **** * : :. : *: :*.****:::*: :: * : * : * .. ** ***: *****::.*:.***:*:*:* *.: : :****:*****:: :.: .. ****:.***** **.*: . ", "identical_positions": 361, "similar_positions": 226, "identity": "46.34%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-40", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LC42-1", "uniprot_id": "A0ABK0LC42_RAT", "id": "A0ABK0LC42-1", "name": "", "aln": "MSMEQDTRALLPTQGTAWATASVPVARLQGPQGDSHQACSQEPHSPPSAEAPYCDLPRCPPALQDPLHTTTCVGQSVDNLGLGLDQEPQRIGSPTTALPAD-----PRNRHRDPEAIPYLEGPAYS------TDEHKDEDPNSNTSSSQDSNTPHDTSNSSSVDWDTVERPG-VVPNRNRLTMMIPRRPQEGLRTDSAQKV----TRSPARGDTAGQRKENSGSGGQSAGQHWVKLRSESGYFSLERQRSGQTQASSGTPPSGPR-TTTQASSAQRDVSQAASAQEAPQTSSLPRNTQRDTQRS----------------------------------------------TPRTSSPSRVSQRDTPRIMSTQ--------------------------------------RKNTPLSSPLRPTPETLKTSAPE--------------DGPHVTSP----------LCAQ--------DSSLNRTTQ--------------------------------------------------------------------------------------------------------------------------------------------------RDSSRTSCAQRNNPRTSSPNRTTQRDNPRTSCAQRNNPRTSSPNRTTQQDNPRTSCAQRNNPRTSSPSRTTQHDNPRTSCAQRDNPRTSSPNRTTQQDNPRMSCAQRNNPRTSSPNRTTQRDNLRTSCAQRNNPRTSSPNRTIHQDNPRTSCVSQNTPRTS----------------------------------------------STQVDKTTASCSRWEHLRSACTQRD----------NPRTLS-QGCTQKDNPGPSSPHRATQGSSSRNPSPHRTNKDIPWASFPLRPTQSDSSRTSSPSRTKQNQVPWASISLRPTQGDKPQTSAPSKLAHNDPPQQ-YSPS----LATSSSSSHNPGHPSASRTSSPLHPAPRGAPQTSLEPSQPPCAVCIGHRDAPRASSPPRYFQYDPFPFFPDPRSSESESPHHEPPYMPPAVCIGHRDAPRATSPPRHTQFDPFPFLPDTSDAEN--ESPQHDPPQFPPPVCIGYRDAPRASSPPRQFPEPS-FFQDLPRASTESLVPSTDSMHEPPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPSVDSLHGSPLLLPQVCIGHRDAPRASSPPRHPPSDVGILAPSPPPGSSG-SRGSAPPGETRHNLEREEYTMLADLPPPRRLAQRVPEPQAQGSNEGRTRSPGRAEVERLFGQERRKSEAPGAFQARDEGRSQRPSQGQSQ-LRRQSSPAPSRQVTKPSAKQAEPTRQSRTGPPHPKSPEKHSEGDRQLQRIAPPARTSARPPERKAQIERHLESGYTGLRQPLGGWQSREGLSGPQSPNRHPEKNWGSQEEGLSLGGWPELGGPSL------EGIWRGPPQEHRERWGQSEAWEEPPSNGIQGGPPRGQGSLQELPRPHQPPPSPENSWAGPAECFCARQPEAGTAMGWRAEGTSPHQYSAERPPDLDWRDLLGLLRAPEDGAWTRLPRLDWEGLLELLQARLPQKDPTRHSRDPAKAPGPEPGSSDTEDTLKTESQTQPEGWAKATLANGHRPGQQSESPAQLPSPACTSTQWPTTKVTSGPETSPPVALEQIDHLESHS------PPDLG--PEEPEASEPSRGEDSLADQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDRPALFNPYLLSLGVLRWQRPDLLNFKKGWMSILDEPGE-------------WKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSECNKENTLHGYGTQKSSLKIGEQRTGSEVIGRGGPRKVDGSRQSLDYVELSPLTPSSPQRVRTLSRSTPERPSKQEDLERDLAQRSEERRKWFES-TDSRTPETPSGDGSRRGLGAPLTDDQQSR----LSEEIEKKWQELEKLPLRENKRVPLTALLNQGHSERRGPTSDSHEALEKEVQSLRAQLEAWRLRGEAPQNAPRLQEDSHIPPGYISQEACERSLAEMESSHQQVMEQLQRHHERELQRLQQEKEWLLAEETAATASAIEAMKKAYQEELSRELSKTRSLQQGPDSLRKQHQLDMEALKQELQVLSERYSQKCLEIGALTRQAEEREHTLRCCQQEGQELLRHNQELHSHLSEEIDRLRSFIASQGTGNSCGRSNERSSCELEVLLRVKENELQYLKKEVQCLRDELQVIQKDKRFT-GKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEAVRNSLAE--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KW3-3", "uniprot_id": "TARA_MOUSE", "id": "Q99KW3-3", "name": "TRIO and F-actin-binding protein", "aln": "MSMEQDTRALLPTQGTAWATASAPVARLQGPQGDSHQACSQEPHSPSSAEAPYCDLPRCPPALQNPLRTTTCVGQSVHSLGLGLGQEPQRVWSPTTALPAEGPAAAPKNRHQDSEGIPYLEGLARSSCTDDNDNKDEDEDPNSNTSSSQDSNTPHDTSNSSSVDWDTTERPG-VVPSRNRLTEMIPRRPQEGLRADSARKA----TRSPARGDTAGQRKENSGSGGQSAGQHWAKLRSESGYFSLERQRSGQTQASSGTPPSGPR-GTTQASSAQRDVFQAAPAQEAPQTSSLPRNTQRDTQRS----------------------------------------------TPRTSSPSRVSQRDTPRVMSTQ--------------------------------------RKNTPLSSPLRATPETLKISAPE--------------DGTHVTPS----------PCVQ--------DSSLNRTSQ--------------------------------------------------------------------------------------------------------------------------------------------------RDSSRTPCIQWDNPRASSPNRTTQRDNPRTPCTQRDNPRASSPNRTTQRDNPRTPCTQRDNPRASSPNRTTQRDNPRTPCAQRDNPRAASPNRSTQRDSPRTPCAQRDNPRASSPNRTAQRDNPRTPCAQR--------------DNPRTSCTSQNTPRTP----------------------------------------------STQADKTTASCSKWEHLRSACTQRD----------NPRTFS-QGCTQKDNPGPPSPRRATQGSNSRNPSPHRTNKDIPWASFPLRPTQSDSPRTSSPSRTKQNQVPWASISLRPTQGDKPQTSAPTRLAHNDPPQQ-YSPS----LATTSSSSHNPGHSSASRTSSPLHAAPRGAPQTSLESSQPPCTVCIGHRDAPRASSPPRYFQYDPFPFFPDPRSSESESPHHEPPYMPPAVCIGHRDAPRATSPPRHTQFDPFPFLPDTSDADN--ESPQHDPPQFPPPVCIGYRDAPRASSPPRQFPEPS-FFQDLPRASTESLVPSTDSMHEPPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPSIDSLHGCPLLPPQVCIGHRDAPRASSPPRHPPSDIGLLAPSPPPGSSG-SRGSAPPGETRHNLEREEYTMLADLPPPRRLAQRGPEPQAQGSNEGRTRSPGRAEVERLFGQERRKSEAPGAFQTRDEGRSQRPSQAQSQ-LRRQSSPAPSRQVTKPSAKQAEPTRQSRTGPPHPKSPDKRPEGDRQLQRTSPPARTPARPPERKAQIERHLESGHTGPRQSLGGWQSQERLSGPQSPNRHPEKSWGSQKEGPSLGGWPELEGPSL------EGIWRGPPQEHREQWGHSEAWEEPPSNGIQGAPPRGQGRLQELSRPHQPTPSSENSWAGPAECSCALQPEASTAVGWRAEGTSPHQRSAERPPDLDWRDLLGLLRAPEDGAWTRLPRLDWEGLLELLQARLPQKDPARHWHDPAKASGPEQGSSGTEDTLKTEPQTQPEGRAKATLANGHRPGQQSESPAQLPSPACTSTQWPTTKVTSGPETSPLAALEQIDHLESHS------PPDLEFQPEEPEASEPSRGEDSRAVQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDRPALFNPYLLSLGVLRWQRPDLLNFKKGWMSILDEPGE-------------WKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDCNKENTLHGYGTQKSSLKIGEQRTGSEVIGRGGPRKADGPRPSLDYVELSPLAPSSPQRMRTLSRSTPERPTKQEDLERDLAQRSEERRKWFES-TDGRTPETPSGDGSRRGLGAPLTDDQQSR----LSEEIEKKWQELEKLPLRENKRVPLTALLNQAHNDRRGPTSDSHEALEKEVQSLRAQLEAWRLRGEAPQNAPRLQEDSHIPPGYISQEACERSLAEMESSHQQVMEQLQRHHERELQRLQQEKEWLLAEETAATASAIEAMKKAYQEELSRELSKTRSLQQGPESLRKQHQLDMEALKQELQVLSERYSQKCLEIGALTRQAEEREHTLRRCQQEGQELLRHNQELHSHLSEEIDRLRSFIASQGTGNSCGRSNERSSCELEVLLRVKENELQYLKKEVQCLRDELQVIQKDKRFT-GKYQDVYVELNHIKTRSEREIEQLKEHLRLAMAALQEKEAVRNSLAE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2D6-1", "uniprot_id": "TARA_HUMAN", "id": "Q9H2D6-1", "name": "TRIO and F-actin-binding protein", "aln": "--MEEVPGDALCEHFEANILTQNRCQNCFHP-EEAHGARYQELRSPSGAEVPYCDLPRCPPAPEDPLSASTSGCQSVVDPGLRPG--PKRGPSPSAGLPEEGPTAAPRSRSRELEAVPYLEGLTTS------LCGSCNEDPGSDPTSSPDSATPDDTSNSSSVDWDTVERQEEEAPSWDELAVMIPRRPREGPRADSSQRAPSLLTRSPVGGDAAGQKKEDTGGGGRSAGQHWARLRGESG-LSLERHRSTLTQASSMTPHSGPRSTTSQASPAQRDTAQAASTREIPRASSPHRITQRDTSRASSTQQEISRASSTQQETSRASSTQEDTPRASSTQEDTPRASSTQWNTPRASSPSRSTQLDNPRTSSTQQDNPQTSFPTCTPQRENPRTPCVQQDDPRASSPNRTTQRENSRTSCAQRDNPKASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPSRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRAARDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRATRDNPTTSCAQRDNPRASRTSSPNRATRDNPRTSCAQRDNPRASSPNRTTQQDSPRTSCARRDDPRASSPNRTIQQENPRTSCALRDNPRASSPSRTIQQENPRTSCAQRDDPRASSPNRTTQQENPRTSCARRDNPRASSRNRTIQRDNPRTSCAQRDNPRASSPNRTIQQENLRTSCTRQDNPRTSSPNRATRDNPRTSCAQRDNLRASSPIRATQQDNPRTCIQQNIPRSSSTQQDNPKTSCTKRDNLRPTCTQRDRTQSFSFQRDNPGTSSSQCCTQKENLRPSSPHRSTQWNNPRNSSPHRTNKDIPWASFPLRPTQSDGPRTSSPSRSKQSEVPWASIALRPTQGDRPQTSSPSRPAQHDPPQSSFGPTQYNLPSRATSSSHNPGHQSTSRTSSPVYPAAYGAPLTSPEPSQPPCAVCIGHRDAPRASSPPRYLQHDPFPFFPEPRAPESEPPHHEPPYIPPAVCIGHRDAPRASSPPRHTQFDPFPFLPDTSDAEHQCQSPQHEPLQLPAPVCIGYRDAPRASSPPRQAPEPSLLFQDLPRASTESLVPSMDSLHECPHIPTPVCIGHRDAPSFSSPPRQAPEPSLFFQDPPGTSMESLAPSTDSLHGSPVLIPQVCIGHRDAPRASSPPRHPPSDLAFLAPSPSPGSSGGSRGSAPPGETRHNLEREEYTVLADLPPPRRLAQRQPGPQAQCSSGGRTHSPGRAEVERLFGQERRKSEAAGAFQAQDEGRSQQPSQGQSQLLRRQSSPAPSRQVTMLPAKQAELTRRSQAEPPHPWSPEKRPEGDRQLQGSPLPPRTSARTPERELRTQRPLESGQAGPRQPLGVWQSQEEPPGSQGPHRHLERSWSSQEGGLGPGGWWGCGEPSLGAAKAPEGAWGGTSREYKESWGQPEAWEEKPTHELP----------RELGK-RSPLTSPPENWGGPAESSQSWHSGTPTAVGWGAEGACPYPRGSERRPELDWRDLLGLLRAPGEGVWARVPSLDWEGLLELLQARLPRKDPAGHRDDLARALGPELGPPGTNDVPEQESHSQPEGWAEATPVNGHSPALQSQSPVQLPSPACTSTQWPKIKVTRGPATATLAGLEQTGPLGSRSTAKGPSLPELQFQPEEPEESEPSRGQDPLTDQKQADSADKRPAEGKAGSPLKGRLVTSWRMPGDRPTLFNPFLLSLGVLRWRRPDLLNFKKGWMSILDEPGEPPSPSLTTTSTSQWKKHWFVLTDSSLKYYRDSTAEEADELDGEIDLRSCTDVTEYAVQRNYGFQIHTKDAVYTLSAMTSGIRRNWIEALRKTVRPTSAPDVTKLSDSNKENALHSYSTQKGPLKAGEQRAGSEVISRGGPRKADGQRQALDYVELSPLTQASPQRARTPAR-TPDRLAKQEELERDLAQRSEERRKWFEA-TDSRTPEVPAGEGPRRGLGAPLTEDQQNR----LSEEIEKKWQELEKLPLRENKRVPLTALLNQSRGERRGPPSDGHEALEKEVQALRAQLEAWRLQGEAPQSALRSQEDGHIPPGYISQEACERSLAEMESSHQQVMEELQRHHERELQRLQQEKEWLLAEETAATASAIEAMKKAYQEELSRELSKTRSLQQGPDGLRKQHQSDVEALKRELQVLSEQYSQKCLEIGALMRQAEEREHTLRRCQQEGQELLRHNQELHGRLSEEIDQLRGFIASQGMGNGCGRSNERSSCELEVLLRVKENELQYLKKEVQCLRDELQMMQKDKRFTSGKYQDVYVELSHIKTRSEREIEQLKEHLRLAMAALQEKESMRNSLAE--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B0C4-1", "uniprot_id": "A0A8M3B0C4_DANRE", "id": "A0A8M3B0C4-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTRLEASLQRSESRSVIEMPSRRESANASRRGSISMSRRESVSQQHSETRRETEQSNGRG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IFKRANRFLSQDREQDDGSSSSPVRHYERGHALPANHSPE----RKAAIPFRNPDLGLPSYRRRYDNLSEQAISGLSPQRHMSYSNFRRGDSQSRASPRSGSPRSTNISPQRRGESRSSSYRR----------------------------------------------------------------------------------------------------------------GSSTHGHRMSSQQASGKCTPSRRRDSIATRTSSPSRSSGTNKYADS-YSPAHKRSPSQSSYGHSLDSEKLYKNLKSIVSSAESDGYDERNGWSKR--------------IQSDDGGYNERNHSGRSSRKSGSHRSGYNSRDFSPTGSN---CDTIKSRNTGRNS-----------------RNSGASTPHRN---------YDERDTVKNSTSKNKSRRN--EVYSDISDKQS----------------------------------------------------------------------------------------------------------------------------KSDSRQSLSPTHSPLSPTSPASTPSIAQSRRSRNQAP--------------------TPDLTKSQTLTPETDKPAIDRSRSNIRRGLEALILSENPRSSSQ------------------------------------------------------PAVPEMTIEDYVIIADIP---RSKLYPEEEEAIIVRRR--------------------PQSRSPRRDNQHSYEDGR------------------------------------------------------------------------------------------------YGYEHEVSEERGRGRERERGRDRREKE------------------------------------------RRRLDKEMGGSSKANSTTSGHSQKSNKNGDIRMTNGGHRGQEKPPPMQG---------------------------------------------------------------------------------------------------------------------------------WMYLLDEDEE-------------WRKFWFVITDSGLRYYRDSEAEERDEADGEVYLRHCLRVEEFDADKNYGLQLHMRDGLVTLSAMTSRIRRNWIDTLRRKISFRDSADSIQHLDNSDISDRENSSSQNAPSQTSP-------APREPCSDDGGLYEDEPDITCSPLTN---------------RREAGEGRDREHERRLEDRTKWFQEGVSDREGDDPWDKVELKKGGTPVVLTQLQVPKAKTGPDIEKKWEDFEQLPIGEKRSLVGSQNPQAAN-----------EALQREVLSLRQQIESLRQVRVGALCGP--------------EAPCALRLQQMEEEHRERLKEIHEQHERERRDMETEKQRLLQEEAKNTLQAMEALRKTHQEEIERLKGHGGEELTDPS--IKQQLHESLSLQRELDGLSQRYSQQCVELNRIQSGTDERDGQIRQKERDMEQLRMENQELQARLTEEISLMRSFITGQRSGVVPLGSYERSTSELEMLLKVKESEVEFLHKEISCLRKEVQTLTKENEALGERYKEVYVELSELRGRSERDINALKQHLKLTDAALEEGRLLGNSDNQ--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q27421-4", "uniprot_id": "OSP_DROME", "id": "Q27421-4", "name": "Protein outspread", "aln": "----MSTTTITTTVPAAPSKSAPPTPTTTGAAGATTNARTADCRKFTPNIFNKSKCSHCFRQREEHSAAALECNRRTSSNLAEPASRKVSKCGYLFVAPDWDFSNPLYRTKRWQRRWFVLYDDGELTYSVDDYPETIPQACVDMTKVLEVTSAVEVTGHPNSIAITAPERVTFVKGTSSEESQWWLNILAAFPKSKGRHKR----SATLPGGQVVGSLRPTSNGDLTLS----TKLGNRHSSYHKDTLTSSQSAGNLLSSLDLGPSSTKTAGSPLTTTQSALADDEEDDGVETGEDVDEDEEDE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSVPRKSKTVSMGGQDENNRNAGNEITNRVSQPTTCLLIEDIRRDEKTIKDIANTITNLSQQQNKRWSTAVNNALNNQHHFGHHSQYQVTSRDETDFQMSSNSSSTKSQNPASERPKSLPLASNSTP--------------------------------------------------------------------------------------------------------------AIVSAIVKKIPTVMEQGDKTKPTARLQLHLKSPKHYQHERGDPDGGCNLDELCVNYMAKTDELRSVGKANSKSSSGQGKPPVKEESLNAKKGWLMKQDNRTCEWSKHWFTLSGAALFYYRDPLCEERGVLDGVLDVNSLTSVIPEPAASKQHAFQLTTWDKQRLVLASLSPSSRNSWLAVLRSAAGLPQLDTPPKQTDIEQDFIKAQLQQPSSSPVTPGTPAGPHFSSDEEYRT----------------------------------------------------------------------------------------------------------------------ASEGGRRDSLDWGSPLSPSPPVLRSCLRNRSLASLHKRSRSSPPSSRRSTVDSVASDELPLLVVPEEMQPTESRELKQQCETLRAEASLREARMSELLATLQRTEQQLTARLQEQQQQLNSELTQAK-------------QSASDLMHNLGMQLTESQCQIKQLEDRLAQGIEENEGLYKRLRELQAQDHSGGAALSNLQRHKIKRMDSLSDLTTISDIDPYCLQRDSLAEEYNELR------------------------------------------------------------------------------------------------SRFEKAVNEIRAMKRELKQSQNQYDALELAQAALQQKLERRQHEDGAQLQLMAARIQDLTLKYSSSERQVRALKQKLAKSERRRSLSLKGKEQLELKLSELQRETVERKEGTPPESSSSESSSQSP--------------------------------------------------------------------------------------------------------------LNAHLLQRLHSLEHVLLGSKE-----------RLEQSLTQLQQIRAGQRTRRSVSPMNDRKDGLRQLERALAETCVMVSEQMELTC-LQDSCHKCCDLRQRVEKLSALQQQTETDLQRSEQLLEQRETDLAQALEKCASQEQEQELLLQQ--RQELSEELGRQQERCRRLEKRLELLEREHG----------KQLECLREVYHTEHANAADEQSFRKRYQTEIEQLRTLCEKGLSAMETSHKRLTMDLEQK----HKMEIERLLAEKETALAEETQATLAALDAMRKAHQS---------EVQREVARFKQEFLRQVQRGEQMRGDGAKLKEEDLGELRMEILAFSEKYSIKCVENAALEEKLHMANSKLRHFQQMQQLELRNKQFRAHLASDDPSNDVHFVQGLTSDAREDADCEDSEP-APQILGATATRTTATTTTTATATTTSAAPSETESNPDSDRETADSSRAPPEKMEQSLFVIPSHMLNSSLVPAANASDQSQRSQLYRDLDGPEDGYEPCYRPFDIFAIYQNRLSYQGLKGSSTFGKSLRKSAAQTSPASSEITTTTTAPTTDPKKPSHKQMFKTAAVINIQQQVAQEEKAQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. : . . .. : . . .:.. . : : . : . : . . . . . . : .. : .... * . : . .. : : . : :... : . .. :. :: . . . . . . . . . : . :. : : * . . . : : ::. . .. .: :. . . .* . . .. .:* * : *:.: * : ::. : :. * . . ..: . . : * : : : : . . : : . : . . . :* * :. : . : * * : *. ** *. . ...: : :*. . . : . :.: : : : : : . . . .:*: : . . : :: :. * :: . . . :. . :**: : * *.: : :::** :: :: . .: :::: :.: : : :: * :: : :. ...: : .: ... * : : : . . .:. . ::: : .:: :. . :.* . : . * : : : :: . . : *. . : . . *:. . : : ..: : **: : . . : ", "identical_positions": 34, "similar_positions": 272, "identity": "1.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-41", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BZV2-1", "uniprot_id": "S19A3_HUMAN", "id": "Q9BZV2-1", "name": "Thiamine transporter 2", "aln": "MD-CYRTSLSSSWIYPTVILCLFGFFSMMRPSEPFLIPYLSGPDKNLTSAEITNEIFPVWTYSYLVLLLPVFVLTDYVRYKPVIILQGISFIITWLLLLFGQGVKTMQVVEFFYGMVTAAEVAYYAYIYSVVSPEHYQRVSGYCRSVTLAAYTAGSVLAQLLVSLANMSYFYLNVISLASVSVAFLFSLFLPMPKKSMFFHAKPSREIKK---SSSVNPVLEETHEGEAPGCE------EQKPTSEILSTSGKLNKGQLNSLKPSNVT--VDVFVQWFQDLKECYSSKRLFYWSLWWAFATAGFNQVLNYVQILWDYKAPSQDSSIYNGAVEAIATFGGAVAAFAVGYVKVNWDLLGELALVVFSVVNAGSLFLMHYTANIWACYAGYLIFKSSYMLLITIAVFQIAVNLNVERYALVFGINTFIALVIQTIMTVIVVDQRGLNLPVSIQFLVYGSYFAVIAGIFLMRSMYITYSTKSQKDVQSPAPSENPDVSHPEEESNIIMSTKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99PL8-1", "uniprot_id": "S19A3_MOUSE", "id": "Q99PL8-1", "name": "Thiamine transporter 2", "aln": "MDSSCRTPPSNSWVYPTVILCLFGFFSMFRPSEAFLIPFLSEPSKNLTSPEMTNEILPVWTYSYLATLPPVFVLTDYLRYKPVIMLHVVAFATSYLFLLFGQGVMLMQTAEFFFGVVSATEIAYFAYIYSMVSPEHYQKVSSYCRSITLVAYTAGSVLAQLLVSLTNLPYSSLFYISLACVSVAFFFSLFLPMPKKSMFFHAKSDR-------DDCPKPLEQCTVPKEAQ---------SNRTHSELFANSKNLEDREMSNPDPENSA--LRHFAHWFQDLKECYSSKHLVYWSLWWAFATAGYNQILNYVQVLWEHKAPSQDSSIYNGAVEAIATFGGALASFSVGYLKVNWDLLGELGLAVFSAVIAGSLFLMNYSRSIWVCYAGYLLVKSSYSFLITIAVFQIAVNLSLERYALVFGIDTFIALVIQTIMTMIVVDQRGLQLPVTTQFLVYGSYFAVIAGVFLMRSIYILCSAKCRKEVQNLATTRSPNEPHPQEPSN--VSTKF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F6V3-1", "uniprot_id": "E7F6V3_DANRE", "id": "E7F6V3-1", "name": "", "aln": "METLKRW--MKDWKYPTSLLFIYGFFSTVKPLEPFLYPFLTGPDKNLTTEQLNNQIFPVWTYSYLAVLVPVFLLTDWLRYKPVVVFQSLILFCTTSMLLWCNGVPEMQAMQFTYGVVTSCDVAYFTYIYSMVEIKHYLKATSYCRTAHLLGYTVGSVLGQILVSLELMSYNNILVFTLVLTGIAMIASILLPMPKVSMFFHKKQSEEDDNEGHSGNVKPLEPEEGFGTMVDLSNDVKVDETKWQQDVLDGSNGCDSSSAKSSKSSRKAGCGDVLLRLWRDFLQCFSSRTLLLWSAWWALATCGYNQTVNYVQSLWEHVEPSSNFTVYNGGAEALSNLFGAAAAYGIGLSSADWSRWGEMALSALSALEGGALFAMVFSGNIWVCYGGYILFKSLYMLLITIAMFQIAAGLNMERYALVFGANTFCALVLQTIITSVVVDSRGLGVDVVTQFIINGAYFSVIAVIFFLRGLYTTMCRK-----PETDTSRENLEEAFKKDAQIVTETKL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * ..* *** :* ::**** .:* *.** *:*: *.****: ::.*:*:********. * ***:***::*****:::: : : : :**: :** **. :* :*:*:: ::**::****:*. :** :.:.***: * .**.****.*:**** :.* : ::*. ..:*:: *::***** ***** * .. .. :*: . : .::: * :. . .. .... : : : ::*: :*:**: *. ** ***:**.*:** :**** **:: **.: ::***..**::.: ** *::.:* ..:*. **:.* .:*.: .*:** * :: .**.**.**::.** * :*****:****..*.:******** :** ***:***:* :***.*** : * **:: *:**:*** :*::*.:* . * . .:.. :: :: .**:", "identical_positions": 192, "similar_positions": 171, "identity": "37.8%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-42", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZN69-1", "uniprot_id": "A0A8I5ZN69_RAT", "id": "A0A8I5ZN69-1", "name": "", "aln": "-----------------------------------------MRTQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQCNVAYSCTRQQNCPIDRTSRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQ--QQQREQVAKTPPAGSHGADTLTYTLGVPDGQLPLGASPDLPEAS--ACPPGLLRASGSGPPYSN-TLAKTEVQGASCHLEYSPERGKAEGRDSIYSTDGQLTLGRRGL--------QLGEPEQGSDSHCSPSFCSAPEAPYASLTDIEYLVQNVCKSYRETCQLRLEDLLRQRTNLFSREEVTSYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIILLKAGAMEVVLVRMCRAYNANNHTVFFEGKYGGVELFRALGCS--ELISSIFDFSHFLSALCFSEDEIALYTALVLINANRPGLQEKRRVEHLQYNLELAFHHHLCKTHR-----QGLLAKLPPKG-KLRSLCSQHVEKLQDFQHLHPIVVQAAFPPLYKELFSTDIESSEGLSK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51450-1", "uniprot_id": "RORG_MOUSE", "id": "P51450-1", "name": "Nuclear receptor ROR-gamma", "aln": "--------------------MDRAPQRHHRTSRELLAAKKTHTSQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQCNVAYSCTRQQNCPIDRTSRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQ--QQQQEQVAKTPPAGSRGADTLTYTLGLSDGQLPLGASPDLPEAS--ACPPGLLRASGSGPPYSN-TLAKTEVQGASCHLEYSPERGKAEGRDSIYSTDGQLTLGRCGLRFEETRHPELGEPEQGPDSHCIPSFCSAPEVPYASLTDIEYLVQNVCKSFRETCQLRLEDLLRQRTNLFSREEVTSYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIILLTAGAMEVVLVRMCRAYNANNHTVFFEGKYGGVELFRALGCS--ELISSIFDFSHFLSALCFSEDEIALYTALVLINANRPGLQEKRRVEHLQYNLELAFHHHLCKTHR-----QGLLAKLPPKG-KLRSLCSQHVEKLQIFQHLHPIVVQAAFPPLYKELFSTDVESPEGLSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51449-1", "uniprot_id": "RORG_HUMAN", "id": "P51449-1", "name": "Nuclear receptor ROR-gamma", "aln": "--------------------MDRAPQRQHRASRELLAAKKTHTSQIEVIPCKICGDKSSGIHYGVITCEGCKGFFRRSQRCNAAYSCTRQQNCPIDRTSRNRCQHCRLQKCLALGMSRDAVKFGRMSKKQRDSLHAEVQKQLQQRQQQQQEPVVKTPPAGAQGADTLTYTLGLPDGQLPLGSSPDLPEAS--ACPPGLLKASGSGPSYSN-NLAKAGLNGASCHLEYSPERGKAEGRESFYSTGSQLTPDRCGLRFEEHRHPGLGELGQGPDSYGSPSFRSTPEAPYASLTEIEHLVQSVCKSYRETCQLRLEDLLRQRSNIFSREEVTGYQRKSMWEMWERCAHHLTEAIQYVVEFAKRLSGFMELCQNDQIVLLKAGAMEVVLVRMCRAYNADNRTVFFEGKYGGMELFRALGCS--ELISSIFDFSHSLSALHFSEDEIALYTALVLINAHRPGLQEKRKVEQLQYNLELAFHHHLCKTHR-----QSILAKLPPKG-KLRSLCSQHVERLQIFQHLHPIVVQAAFPPLYKELFSTETESPVGLSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HJG5-1", "uniprot_id": "A0AC58HJG5_DANRE", "id": "A0AC58HJG5-1", "name": "", "aln": "--------------------MDHYYGGESDTG-YLAWRIKTIQAQIEVIPCKICGDKSSGVHYGVITCEGCKGFFRRSQSSSVQYSCSRQSNCPIDRASRNRCQSCRLKKCVAQGMSRDAVKFGRMSKRQRDSLFAEVERHRQH--QRLQANSVQEPQP------LQAYRSSKDTREQPSHLIPPLPAAYPFSVEPELAGCPAEVIPYLDCHIVEAQTQGLAYRVPLR--RGENNSLSAGRGFESTRSTPESILN------------MTGSEMGFHPFDPESSFFSYPTSLQTEELAASIIRSHKETTQYRLEELQALRWKVFSREEVHIYQSKPVDEMWQYCAVRLSDAVQYVVEFAKRIPGFRQLCQNDQIALLKSGSMEVVLVRMTRMFNTANNTVFFDGKYAGTELFKSLACS--DLIAAVFEFANNLCALRLNEQQMAVFTAMILINPDRPCLEDRERVQRVRTEVELALRHILHRDNQ-----ESLLQKLYQRVPVLRSMCALHIEKLQWFRQLYPLTVHSLFPPLYKELFGSDADIHSLTTH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P31396-1", "uniprot_id": "HR3_DROME", "id": "P31396-1", "name": "Probable nuclear hormone receptor HR3", "aln": "MYTQRMFDMWSSVTSKLEAHANNLGQSNVQSPAGQNNSSGSIKAQIEIIPCKVCGDKSSGVHYGVITCEGCKGFFRRSQSSVVNYQCPRNKQCVVDRVNRNRCQYCRLQKCLKLGMSRDAVKFGRMSKKQREKVEDEVRFHRAQ--MRAQSDAAP---------DSSVYDTQTPSSSDQLHHNNYNSYSG----------------GYSN------------NEVGYGSPYGYSASVTPQQTMQYDISAD-----------------YVDSTTYEPRSTIIDPEFISHADGDINDVLIKTLAEAHANTNTKLEAVHDMFRKQPDVSRILYYKNLGQEELWLDCAEKLTQMIQNIIEFAKLIPGFMRLSQDDQILLLKTGSFELAIVRMSRLLDLSQNAVLYGDVMLPQEAFYTSDSEEMRLVSRIFQTAKSIAELKLTETELALYQSLVLLWPERNGVRGNTEIQRLFNLSMNAIRQELETNHAPLKGDVTVLDTLLNNIPNFRDISILHMESLSKFKLQHP---NVVFPALYKELFSIDSQQDLT---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***:****:*******:****************** . . *.*.*:.:* :**..***** ***:**: **************:**:.: **. : : : : . .* . . : * : .: * . . : .. . : : : : . . : . : :** : : . ..: *: *:* ** :*:: :* ::**** :.** .*.*:*** **.:*::*:.:*** * : :.:*:: . * * : .. *:: :*: :: :. * :.* ::*:: :::*: ..* :. . .:::: *::: * : :* .* . :*.:. *:* *. *: :* : **.******. : : ", "identical_positions": 125, "similar_positions": 133, "identity": "22.77%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-48", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q00788-1", "uniprot_id": "V2R_RAT", "id": "Q00788-1", "name": "Vasopressin V2 receptor", "aln": "-MLLVS----------TVSAVPGLFSPPSSPSNSSQEE-----------------------------------------------------------------LLDDRDP----------LLVRAELALLSTIFVAVALSNGLVLGALIRRGRRGRWAPMHVFISHLCLADLAVALFQVLPQLAWDATDRFHGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQRDVGNGSGVFDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHAS-LVPGP-----------------SERAGRRRRGRRTGS-------------------------------------------------------------------------------------------------------------------PSEGAH------VSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWD--PEAPLERPPFVLLMLLASLNSCTNPWIYASFSSSVSSELR------SLLCCAQRHTTHS-----------LGPQDESCATASSSLMKDTPS--------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88721-1", "uniprot_id": "V2R_MOUSE", "id": "O88721-1", "name": "Vasopressin V2 receptor", "aln": "-MILVS----------TTSAVPGALSSPSSPSNSSQEE-----------------------------------------------------------------LLDDRDP----------LLVRAELALLSTIFVAVALSNGLVLGALIRRGRRGRWAPMHVFISHLCLADLAVALFQVLPQLAWDATDRFHGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLLLSLPQLFIFAQRDVGNGSGVFDCWARFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHAS-LVPGP-----------------SERAGRRRRGHRTGS-------------------------------------------------------------------------------------------------------------------PSEGAH------VSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWD--PEAPLERPPFVLLMLLASLNSCTNPWIYASFSSSVSSELR------SLLCCAQRHTTHS-----------LGPQDESCATASSSLMKDTPS--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30518-1", "uniprot_id": "V2R_HUMAN", "id": "P30518-1", "name": "Vasopressin V2 receptor", "aln": "-MLMAS----------TTSAVPGHPSLPSLPSNSSQER-----------------------------------------------------------------PLDTRDP----------LLARAELALLSIVFVAVALSNGLVLAALARRGRRGHWAPIHVFIGHLCLADLAVALFQVLPQLAWKATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGSGAHWNRPVLVAWAFSLLLSLPQLFIFAQRNVEGGSGVTDCWACFAEPWGRRTYVTWIALMVFVAPTLGIAACQVLIFREIHAS-LVPGP-----------------SERPGGRRRGRRTGS-------------------------------------------------------------------------------------------------------------------PGEGAH------VSAAVAKTVRMTLVIVVVYVLCWAPFFLVQLWAAWD--PEAPLEGAPFVLLMLLASLNSCTNPWIYASFSSSVSSELR------SLLCCARGRTPPS-----------LGPQDESCTTASSSLAKDTSS--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QV55-1", "uniprot_id": "A0A8M1QV55_DANRE", "id": "A0A8M1QV55-1", "name": "", "aln": "-MRIASWEDNLGQPNHSVLEMEGPPDLSSSLFNLSSSYGGTGAFLWLYPSENVTWTTM-------------------------------------RPTMQPVTPPRVRDQ----------ALAQAEIGVLGLVLALTALGNGFVLWVLLR--RKKNHAPMHLFMVNLCVADLVVAFFQVLPQLVWDITERFHGPDALCRSVKYLQIVGMFASSYMIVAMTVDRHYAICCPLQAYRGGATSRWNTPIMVAWGLAFVLSLPQVFIFSQSEVS--PGVFECWGHFAEPWGLKAYVTWMTVAVFVLPALIITVCQVRIFREIHDN-IYLKSERVVTAEFKKNSVFFHFPRREGGRGRTRKKNERSRQSRHSQQGEISLSQAHCSRSHHAGQEEFSSNLYDEYSQTLPCRSSMCEPCFGPCPSSDPSIPNHLQNSPNNLSDPTHSQSLSANSVCALAGHTESSGASELWPDVLPDAFPLPTEYSHPPPVPGVTKAMSKTVRMTLVIVLVYTICWSPFFIVQLWAAWD--PNPPIQGAVFTILMLLASLNSCTNPWIYTAFSSSVSRELL------ALLRCHRRSPRRG-----------SLP-DDSTATHTSTNTKDSIY--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q868T3-1", "uniprot_id": "CCAPR_DROME", "id": "Q868T3-1", "name": "Cardioacceleratory peptide receptor", "aln": "MLHLRLFDSSLYYTLASASESSGLASSTSTERSFNGTQGAGGVAAGGESLTPTDVAAVNLTYFTPAISHVMLAPTTIATTTASATMVQIQTTAAPSHDLETGGNSTSSDPGEFDNLNSFYFYETEQFAVLWILFTVIVLGNSAVLFVMFIN--KNRKSRMNYFIKQLALADLCVGLLNVLTDIIWRITISWRAGNLACKAIRFSQVCVTYSSTYVLVAMSIDRYDAITHPMNFSKSWKRARH--LVAGAWLISALFSLPILVLYEEKLIQ---GHPQCWIELGSPIAWQVYMSLVSATLFAIPALIISACYAIIVKTIWAKGSIFVP-----------------TERAGFGAAPARRAS--------------------------------------------------------------------------------------------------------------------SRGIIP-------RAKVKTVKMTLTIVFVFIICWSPYIIFDLLQVFGQIPHSQTNIAIATFIQSLAPLNSAANPLIYCLFSSQVFRTLSRFPPFKWFTCCCKSYRNNSQQNRCHTVGRRLHNSCDSMRTLTTSLTVSRRSTNKTNARVVICERPTKVVTVPAMSEV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :. * . .* . . * ::.:* ::. .*.*. ** .: : . : :: *: :*.:*** *.:::**.:: * * ::. : *::::: *: ::*:*:::**::**: ** *: : :: : ** :: ::*** :.:: : : * :** :..* . :.*:: :: :*. *:* *:.* . *.: * . . ..* * : . . * ***:***.**.*: :**:*:::.:* .:. *.. : . .:: **.***.:** ** ***.* * : * : . :* * ::: . ", "identical_positions": 80, "similar_positions": 129, "identity": "12.48%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-52", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZBM7-1", "uniprot_id": "HACE1_RAT", "id": "D3ZBM7-1", "name": "E3 ubiquitin-protein ligase HACE1", "aln": "MERAMEQL----NRLTRSLRRARTVELPEDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVTDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVAGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGGYGQTCEVLIQYHPRLFQTIVQMTQNEDLRENMLRQVLQHLSQQSESQYLKILTGLAEVATTNGHKLLSLSSSYEAQMKSLLRIVRIFCHVFRIGPSSPSNGMDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLIATELMKNKEDSADITSILLKQKGQDQEASCISAFEPPGPGSYERLSTGPGESKPDVLAGKQEASADCQDVISVTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVSENDILLVHRDSIFRSSCEIVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVNDWIKNTEYTSGYEREDPVIQWFWEVVEDMTQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U0D9-1", "uniprot_id": "HACE1_MOUSE", "id": "Q3U0D9-1", "name": "E3 ubiquitin-protein ligase HACE1", "aln": "MERAMEQL----NRLTRSLRRARTVELPEDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVTDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGGYGQTCEVLIQYHPRLFQTIVQMTQNEDLRENMLRQVLQHLSQQSESQYLKILTGLAEVATTNGHKLLSLSSNYDAQMKSLLRIVRIFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLIATELMKNKEDSTDITSILLKQKGQDQEAPSLSAFEPPGPGSYESLPPGPGDSKPEVLAGEQEASADCQDVISVTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVSENDILLVHRDSIFRSSCEIVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVNDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IYU2-1", "uniprot_id": "HACE1_HUMAN", "id": "Q8IYU2-1", "name": "E3 ubiquitin-protein ligase HACE1", "aln": "MERAMEQL----NRLTRSLRRARTVELPEDNETAVYTLMPMVMADQHRSVSELLSNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDKNGVTPLDLCVQGGYGETCEVLIQYHPRLFQTIIQMTQNEDLRENMLRQVLEHLSQQSESQYLKILTSLAEVATTNGHKLLSLSSNYDAQMKSLLRIVRMFCHVFRIGPSSPSNGIDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLIATELMKNKRDSTEITSILLKQKGQDQDAASIPPFEPPGPGSYENLSTGTRESKPDALAGRQEASADCQDVISMTANRLSAVIQAFYMCCSCQMPPGMTSPRFIEFVCKHDEVLKCFVNRNPKIIFDHFHFLLECPELMSRFMHIIKAQPFKDRCEWFYEHLHSGQPDSDMVHRPVNENDILLVHRDSIFRSSCEVVSKANCAKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIVNPDYALFTQSADGTTFQPNSNSYVNPDHLNYFRFAGQILGLALNHRQLVNIYFTRSFYKHILGIPVNYQDVASIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGAMEEVPLKPGGGSILVTQNNKAEYVQLVTELRMTRAIQPQINAFLQGFHMFIPPSLIQLFDEYELELLLSGMPEIDVSDWIKNTEYTSGYEREDPVIQWFWEVVEDITQEERVLLLQFVTGSSRVPHGGFANIMGGSGLQNFTIAAVPYTPNLLPTSSTCINMLKLPEYPSKEILKDRLLVALHCGSYGYTMA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F8W2M1-1", "uniprot_id": "HACE1_DANRE", "id": "F8W2M1-1", "name": "E3 ubiquitin-protein ligase HACE1", "aln": "MERAMEHLNVQLNRLTRSLRRARTVELPEDSETAVYTLMPMVMADQHRSVSELLLNSKFDVNYAFGRVKRSLLHIAANCGSVECLVLLLKRGANPNYQDISGCTPLHLAARNGQKKCMGRLLEYNADVNICNNEGLTAIHWLAVNGRTELLHDLVQHVTNVDVEDAMGQTALHVACQNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGAKYLPDRNGVTPLDLCVQGGYGETCEILIQHHGRLFQTLIQMTQNDDIKENMLRQVLEHVSQQNDSNYQRILTSLAEVATTNGHKLLSLSSNFEVQTKSLLRIIRIFCHVFCLGPSSPNNGNDMGYNGNKTPRSQVFKPLELLWHSLDEWLVLISTELEKEITDTTRSS------SGNDIASLFLKKQEVDHSVSSENPQLLLDASS---VMKTPEVYADGQDVISMIANRLSAVIQAFYMCCSCQMPHGMTSPRFIEFVCKHDEVLKCFVTRNPKIIFNHFHFLLECPELMSRFMHIIKGQPFKDRCEWFYEHLLAGQPDSDMVHRPVNENDILLVHRDSLFRSSCEVVSKSSNEKLKQGIAVRFHGEEGMGQGVVREWFDILSNEIINPDYALFTQSADGTTFQPNSNSSVNPDHLNYFRFAGQILGLALYHRQLVNIYFTRSFYKHILGIPVSYQDVSSIDPEYAKNLQWILDNDISDLGLELTFSVETDVFGTMEEVPLKPGGTTIQVTQDNKEEYVQLVTELRMTRAIQPQINAFLQGFHTFIPPSLIQLFDEYELELLLSGMPEIDVMDWKRNTEYTSGYDLQEPVIQWFWEVVENLTQEERVLLLQFVTGSSRVPHGGFAFLMGGSGLQKFTVAAVPYTSNLLPTSSTCINMLKLPEYPSKDVLRDRLLVALHCGSYGYTMA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******:* ******************.*********************** ***********************************:***************************.:****.*********************************::***************************************:******************************:***************:***:***:* *****::*****:*::********:*:***.:*:* :***.*****************.::.* ******:*:***** :*****.** ********************************:*** *: *:: : .*:* : : * . * * *. : *. ** *****: ******************** **********************.*******:********************.************** :************.***********:******:***:. ********************************:********************** ******************** **********************.****:***********************************:********** :* ***:** *************************** *************************** ** :********: ::***********::************************ :*******:**:******.*********************::*:*****************", "identical_positions": 773, "similar_positions": 75, "identity": "84.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-53", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O96007-1", "uniprot_id": "MOC2B_HUMAN", "id": "O96007-1", "name": "Molybdopterin synthase catalytic subunit", "aln": "MSSLEISSSCFSLETKLPLSPPLVEDSAFEPSRKDMDEVEEKSKDVINFTAEKLSVDEVSQLVISPLCGAISLFVGTTRNNFEGKKVISLEYEAYLPMAENEVRKICSDIRQKWP-VKHIAVFHRLGLVPVSEASIIIAVSSAHRAASLEAVSYAIDTLKAKVPIWKKEIYEES-STWKGNKECFWASNS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z223-2", "uniprot_id": "MOC2B_MOUSE", "id": "Q9Z223-2", "name": "Molybdopterin synthase catalytic subunit", "aln": "MSSLEISNSCFSPETRSPSSRQSVEDNASEPSGKDVDDVQEKPKDIIQFTAEKLSVGEVSQLVVSPLCGAVSLFVGTTRNNFEGKKVISLEYEAYVPMAENEIRKICNDIRQKWP-VRHIAVFHRLGLVPVSEASTVIAVSSAHRAASLEAVSYAIDSLKAKVPIWKKEIYEESTSSWKRNKECFWAAGD------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M6Z1C5-1", "uniprot_id": "A0A8M6Z1C5_DANRE", "id": "A0A8M6Z1C5-1", "name": "Molybdopterin synthase catalytic subunit", "aln": "----------------------MAADGG---------------RDLITLTTDKLFADRVSESVTCPSCGAVSLFIGTTRDNFEGKKVVRLEYEAYAPMAESKLKKICSHIRTKWPSVRHINIQHRLGLVSVTEASVIIGISSPHRSDSLEALKYCIDTLKATVPIWKKEIYESGEPCWKENKECLWADGGKHPKES", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *.. :*:* :*::** ...**: * .* ***:***:****:*******: ****** ****.:::***..** *** *:** : ******.*:*** :*.:**.**: ****:.*.**:***.**********.. . ** ****:** .. ", "identical_positions": 91, "similar_positions": 43, "identity": "46.43%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-55", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTY5-1", "uniprot_id": "D3ZTY5_RAT", "id": "D3ZTY5-1", "name": "", "aln": "MNDQYHRAARDGYLELLKEATRKELNAPDEDGMTPTLWAAYHGNLESLRLIVSRGGDPDKCDIWGNTPLHLAASNGHLHCLSFLVSFGANIWCLDNDYHTPLDMAAMKGHMECVRYLDSIAAKQSSLNPKLVGKLKDKAFREAERRIRECAKMQRKHHERMERRYRRELAER--SDTLSFSSLTSSTLSRRLQHMTLGSQLPYSQATLHGTAKGKAKIQKKLERRKQGVEGTFKVSEDGRKSVRSLSGLQLGNDVMFVRQGTYANPKEWG--RAPLRDMFLS-----------DEDSVSRATLAA---EPAHSEVSTDSGHDSLFTRPGLGTMVFRRNYVSSGLHGLGREDGGLDG---AG-TP----RGRLHS-SPSLDDDSLGSANSLQDRSCGEELPWDELDLGLDED---LEPETSPLETFLASLHMEDFASLLRHEKIDLEALMLCSDLDLRSISVPLGPRKKILGAVRRRRQALERPLALEDTEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80T11-1", "uniprot_id": "USH1G_MOUSE", "id": "Q80T11-1", "name": "pre-mRNA splicing regulator USH1G", "aln": "MNDQYHRAARDGYLELLKEATRKELNAPDEDGMTPTLWAAYHGNLESLRLIVSRGGDPDKCDIWGNTPLHLAASNGHLHCLSFLVSFGANIWCLDNDYHTPLDMAAMKGHMECVRYLDSIAAKQSSLNPKLVGKLKDKAFREAERRIRECAKMQRKHHERMERRYRRELAER--SDTLSFSSLTSSTLSRRLQHMTLGSQLPYSQATLHGTAKGKAKIQKKLERRKQGGEGTFKVSEDGRKSVRSLSGLQLGSDVMFVRQGTYANPKEWG--RAPLRDMFLS-----------DEDSVSRATLAA---EPAHSEVSTDSGHDSLFTRPGLGTMVFRRNYVSSGLHGLGREDGGLDG---AG-TP----RGRLHS-SPSLDDDSLGSANSLQDRSCGEELPWDELDLGLDED---LEPETSPLETFLASLHMEDFASLLRHEKIDLEALMLCSDLDLRSISVPLGPRKKILGAVRRRRQALERPLALEDTEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q495M9-1", "uniprot_id": "USH1G_HUMAN", "id": "Q495M9-1", "name": "pre-mRNA splicing regulator USH1G", "aln": "MNDQYHRAARDGYLELLKEATRKELNAPDEDGMTPTLWAAYHGNLESLRLIVSRGGDPDKCDIWGNTPLHLAASNGHLHCLSFLVSFGANIWCLDNDYHTPLDMAAMKGHMECVRYLDSIAAKQSSLNPKLVGKLKDKAFREAERRIRECAKLQRRHHERMERRYRRELAER--SDTLSFSSLTSSTLSRRLQHLALGSHLPYSQATLHGTARGKTKMQKKLERRKQGGEGTFKVSEDGRKSARSLSGLQLGSDVMFVRQGTYANPKEWG--RAPLRDMFLS-----------DEDSVSRATLAA---EPAHSEVSTDSGHDSLFTRPGLGTMVFRRNYLSSGLHGLGREDGGLDG---VG-AP----RGRLQS-SPSLDDDSLGSANSLQDRSCGEELPWDELDLGLDED---LEPETSPLETFLASLHMEDFAALLRQEKIDLEALMLCSDLDLRSISVPLGPRKKILGAVRRRRQAMERPPALEDTEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T6J6-1", "uniprot_id": "A0A8N7T6J6_DANRE", "id": "A0A8N7T6J6-1", "name": "", "aln": "MDDRFHRAARDGHLLLLKEATRKHLNAPDEDGMTPTLWAAQHGNVDALRLIVGRGGDPDKCDIWGNTPLHLAAANGHLSCLSFLVSFGANVWCLDNDYHTPLDMAASRSHMDCVRYLDSIAAKQITINPKLVSKLKERGFRNAEKRIRNCEKLQRKHHQRMERHFMRESAALDTSDTMSYSSFSS-TLSRRMPQFNTLDSMTYSQATLQSTARGRTKIQRKLEKKKQ-VEGTFKISEDGRKSVRSLSGLQLGNDVMFLKQGTFVDRRHQSSPRLNIRNMFSGKSDIRLEDVDDEEDTVSRALSDPGLYEAAYSEISTDSGRDSLFNRPGLGTMVFRRNYATDGVFRTGRGEGSVAGSEPVGRAPNIHLRGRLPLRSPSLDEVSIGSSLSLQEKNL-QDLPWEEGDLGLEEEDDELQPSSAPLEVFLASQGLSDYVSIFQREQMDLEALLLCSEQDLISIHIPLGPRKKLLDACRRRNSVMEEAEGMLDTTL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*::*******:* ********.**************** ***:::*****.********************:**** ***********:*************** :.**:************ ::*****.***::.**:**:***:* *:**:**:****:: ** * ***:*:**::* *****: :: . :.******:.**:*::*:*:***::** *****:*******.*********.****::***:.: :. . * :*:** . :**:**** . *.*:**:*****:****.************* :.*:. ** :*.: * .* :* **** *****: *:**: ***::. ::***:* ****:*: *:*.::***.**** :.*:.:::::*::*****:***: ** ** :*******:*.* ***...:*.. .: ** *", "identical_positions": 296, "similar_positions": 118, "identity": "60.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-60", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZVF9-1", "uniprot_id": "GRIN3_HUMAN", "id": "Q6ZVF9-1", "name": "G protein-regulated inducer of neurite outgrowth 3", "aln": "MGTVPDPLRSAKTSLIAASGKEDDLGEPQAASPRHRPALLCKNANGFSGAPAEPDLSPRAAAEALMQVCEHETTQPDMSSPGVFNEVQKAPATFNSPGNPQLPGSSQPAASAPSSAAGRDLIHTPLTMPANQHTCQSIPGDQPNAITSSMPEDSLMRSQRTSNREQPEKPSCPVGGVLSSSKDQ-VSCEFPSPETIQGTVQTPVTAARVVSHSSSPVGGPEGERQGAICDSEMRSCKPLTRESGCSENKQPSVTASGPQGTTSVTPQPTPLTSEPSACPPGPEKVPLPAQRQMSRFKEASTMTNQAESEIKEVPSRAWQDAEVQAVASVESRSVSTSPSILTAFLKESRAPEHFE-QEQLRVICHS--SGSHTLELSDSTLAPQESSQCPGIMPQVHIQAAAAESTAFQRENKLASLPGGVLKTSSINLVSSNAQHTCKEDGRLAGMTPVREESTAKKLAGTNSSSLKATAIDQISISACSQAETSYGLGKFETRPSEFAEKTTNGHKTDPDCKLSDSCGSISKADHSGSLDPTNKGDAREKKPASPQVVKEKESTGTDTSDAKTLLLNPKSQESGGTESAANPTPSPIRKNQESTLEENRQTKTATSLSLPSDPMGDSSPGSGKKTPSRSVKASPRRPSRVSEFLKEQKLNVTAAAAQVGLTPGDKKKQLGADSKLQLKQSKRVRDVVWDEQGMTWEVYGASLDAESLGIAIQNHLQRQIREHEKLIKTQNSQTRRSISSDTSSNKKLRGRQHSVFQSMLQNFRRPNCCVRPAPSSVLD-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BWS5-1", "uniprot_id": "GRIN3_MOUSE", "id": "Q8BWS5-1", "name": "G protein-regulated inducer of neurite outgrowth 3", "aln": "MGTVPDPLRVTKASIVAASGKEESRGESQSVSP--QPAQPDNNASGIGNVPAELSLQLSAAAQALMQACVSESSQQDMASPGVFSEGEPVSPKQKTPDDFLLHGSKESAAPGLNATAQKELISAPCLISVVQHTHHAIQRDAPNTSTCAVPEGSLVKSEANSNGENPEKPGCPARVTCCSSKNQEGLCDFPSPENSQGILQTPDIAS-------PSADRPEGEGQKVINNITAVSSEPPVREG-CSENKQPSATALNTTAERSENPPPSHLTSKGATCSSEARQALLPAQYPVSRFKEASTMTCQAESGAKEVSGRAWQDAEVQAVASVESRSVSTSPSILPAYLKENPAPELENGQEQLRVICHGKGSGNHLLELSNSMVDSQESRQCPSIVPQVHIQAATATPAAFKGGCKPANQPAEGLKSPLIHVTSS-QNTETEEDLRLS----ASKEATSRQPEGTNPDFQKANAIGQISLPAGSQAEINQGLWNSGPREPEIVVKTAKDHKAESSCKPSNSGGGANKDYPPESLDPTDKKGAKDKKPASPLIVKDHAPGATSTLDAKTLLLNPKSQVKEGEGPEVSPAPSPGRKSQQNTLEELRQPKTVMSLSLPSDGTGDSSPGSGKRTPSLSVKASPRRGSRVSEFLKE--LSVTAAAAQVGLTPGEKKKQLGADSKLHLKQSKRVRDVVWDDQGMTWEVYGASLDPESLGVAIQNHLQRQIREHEKIVKTQSGQTRRSISSDSSSSKKLKGRQHGVLQSMLQNFRRPNCCVRPAPSSVLD-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B6U6-1", "uniprot_id": "A0ACD6B6U6_DANRE", "id": "A0ACD6B6U6-1", "name": "", "aln": "----------------------------------------------------------MEPHPALLHTPGSNACWETESNPSGQHRKGNISPEPKTRPEEKQCNEAKEHEKGTSRESVKTLKHTPLASNADLHPASKIP-------TMHTTTTKQITNANKTASKQPAKSSSSGVEVLSSTSGA----KLKSPNVHEKKLQAKLFPKN-------------------IQKAPSTSHIMGSTESPQKMLQKTASASQITSTDSPKSLNRLSLSHIPKASSSPKIKATSPTSLKVDKAERIKKLVSKETPSPKDKP----IDAESKPGAKTALRESPLGPPEIKSGDSSSVLLHRELNPEQPKAPEDK----------TDAYVTTQERKTGKSLREQKEADSTIKN--------------DNMVNNTAYKSSTSKIQKDSETMTHLS--------AIATKDAAIQTEVTNIDAEIQAVVKLCSKSTEMS------------PVRNPQTIRLDSDNNPEANLHNELKPDSNSDSDWLSNGGLMDSTPIG----------------AKPRFLGPPPYKSPN-------TQKPHQHVCQIEIELRSESPQTFGLNPPDVTISDAEKTS------------------------------MKCLGKTGDVDGQKG------------ESAAPQQIVWDEQGMTWEVYGASLDMESLGFAIQSHLQCKIREHERRIGTLR--KSICLSEQSPGKGRTEKRKRNVFRSLFAGS---HCCSKQHPEEGMAK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **::. :: :.*. . .. :: : .. : . . : : * :* . *. * * . . : . .: ::* *.... . .*:.. .: **: : :*: . * . * *. . ::.: :: . . . *: :... :. *:. :.: :. ..:. : . *: . *** :. *.. *. . .*. : : ... . ** :. . ::: : .** .: * . ::: ::.. : :* : : :*: : : : . :.. : * * : *:: :..: : :.. : . . . * . * .: . :..* . **. :*.* . . . : .* :: : :* :. . .*. *. .*:. * . .:.* . *:* :* :::***:************* ****.***.*** :*****: : * . .:*.::... : . *::.*::*:: . :** : *.. : ", "identical_positions": 92, "similar_positions": 213, "identity": "11.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-62", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q810F0-1", "uniprot_id": "PRIMA_MOUSE", "id": "Q810F0-1", "name": "Proline-rich membrane anchor 1", "aln": "MLLRDLVPRHGCCWPSLLLHCALHPLWGLVQVTHAEPQKSCSKVT-----DSCQHICQCRPPPPLPPPPPPPPPPRLLSAPAPNSTSCPAEDSWWSGLVIIVA--VVCASLVFLTVLVIICYKAIKRKPLRKDENGTSVAEYPMSSSQSHKGVDVNAAVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86XR5-1", "uniprot_id": "PRIMA_HUMAN", "id": "Q86XR5-1", "name": "Proline-rich membrane anchor 1", "aln": "MLLRDLVLRRGCCWSSLLLHCALHPLWGFVQVTHGEPQKSCSKVT-----DSCRHVCQCRPPPPLPPPPPPPPPPRLLSAPAPNSTSCPTEESWWSGLVIIIA--VCCASLVFLTVLVIICYKAIKRKPLRKDENGTSVAEYPMSASQSNKGVDVNNAVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FER7-1", "uniprot_id": "E7FER7_DANRE", "id": "E7FER7-1", "name": "", "aln": "MFIRKLLPLNLGFLTFLFSHCFLSLFLPLLQFARGELQKSCSRTTVAPLEGSCQLPCQCRPYPPLPPPPPPPPPPRLLAPTVAPSTVSPMTP-WRREMEILVLGTVICASVVFLLLTAIICYKAIKRKPLRKEENGTSRGEYAMSSRCKQQVVETNNTGV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::*.*: . . *: ** * : ::*.::.* *****:.* .**: ***** ****************:.... ** .* * : *:: * ***:*** : .**************:***** .**.**: .:: *:.* : *", "identical_positions": 76, "similar_positions": 40, "identity": "47.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-68", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y8A9-1", "uniprot_id": "A0A8I5Y8A9_RAT", "id": "A0A8I5Y8A9-1", "name": "", "aln": "MVLGVSLSP-ALGRWFRHAIPFAIFTLLLLYISVWLFHEWPFELPAQRTQQSGLWELKLSSPSPALTSLLPVTSGVLPGCRPGVQSCNPERALPSQIGPALRPLVVPEKEEP-PCLRPHGLLGRMVSPFLACMSPEGDVELSQYLAGWRELLRLLTPLGSVFAFATSEASNKVTALEAH--VHGPDASHYTSLVTMATWERRAV--------------LLERPGTTPRHLARPSGSQTLLLLHRALRWSQLCLHRVATGKLGGPEAGAQCRDAYSTALAPYHPWLIRQAARLAILTLPSRSRLLQLACPGTGEADARVALARAARVLEDVYNRTQGLLASHGLLQLA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K0R6-1", "uniprot_id": "GLTD2_MOUSE", "id": "Q8K0R6-1", "name": "Glycolipid transfer protein domain-containing protein 2", "aln": "MVMGVSLSP-ALGRWFRHAIPFAILTLLLLYISIWFFYEWPFPLPAQRTQQSGLRGLKLPSPSPVLGSLLSFP--------AGVQSCNPERPLPSQTGPAARPLVVPEKEEL-PCLGPHGALGRMVSPFLACMSPEGDVALSQYLAGWRELLRFLTPLGTVFAFATSEAFNKVTDLEAR--VHGPNASHYTSLMTMITWERGAG--------------LLQRPGTEPGHSAGSSGSRTLLLLHRALRWSQLCLHRVATGTLGGPDAGTQCGEAYSTALAPHHPWLIRQAARLAILALPSRGRLLQLACPGTGEADARVALARAAGVLEDVYNRTQGLLAGHGLLQLA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NH11-1", "uniprot_id": "GLTD2_HUMAN", "id": "A6NH11-1", "name": "Glycolipid transfer protein domain-containing protein 2", "aln": "--MGVAARPPALRHWFSHSIPLAIFALLLLYLSVR-------SLGAR----SGCG--------------------------PRAQPCVPGETAPFQVRQESGTLEAPERKQP-PCLGPRGMLGRMMRRFHASLKPEGDVGLSPYLAGWRALVEFLTPLGSVFAFATREAFTKVTDLEAR--VHGPDAEHYWSLVAMAAWERRAG--------------LLEQPGAAPRDPTRSSGSRTLLLLHRALRWSQLCLHRVATGALGGPDAGVQCSDAYRAALGPHHPWLVRQTARLAFLAFPGRRRLLELACPGATEAEARAALVRAAGTLEDVYNRTQSLLAERGLLQLA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8MLW4-1", "uniprot_id": "Q8MLW4_DROME", "id": "Q8MLW4-1", "name": "Glycolipid transfer protein domain-containing protein", "aln": "---------------------------------------------------------------------------------------------------MSKTSLATQTNGT-AENGNCFDILKVSNLFETSLLDEDDVQLDAYLAAYEEIMKFFQLMGSVFSFVSSDVRSKIDILYALRAKDAEEQEHFNTFRTMLDYEKEAQ--------------LLTQKG-------YVSGSRTLLRLHRGLDFVYEFLNRIQA-IPDDQKTVDVCKEAYDDTLGKHHSFLIRKGARLAMYAMPTRGDLLKKVCS--DVEAAKENLPSMLKHMRTNYDRTEDLYTLYDLHSLP", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1Q7P2-1", "uniprot_id": "A0A8M1Q7P2_DANRE", "id": "A0A8M1Q7P2-1", "name": "", "aln": "----------MVSGLGRCLAAAALLSFLLFLSSLWLPQGTVQGCEDS------------------------------------WRPCLSAYKSAKQVDHASIPEELRASDLIRECNGQKFQVSRLLLHLNSALGPASDVLLDPYLLCWEELIKFMEALGPLVGFFTHKVEEKIALIRQLSLEESTRHSVTASNSMMYGAQHEAPPPGHAYHSVHSMLEAELQRGVVSFDQQTPSGSRTLLRLHRSLLWLQLLLEKLGTEREGRS-FGELCREAYLEVLAPHHPWLVQRAAELVFHAMPDRSVFLQLVCVR-TQEEAEPVMRIVVAAIREIHQRTQRELEIRNMLDLP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : :: : :.: .** *. ** :. ::.:: :*.:..* : .. *: : .. . : * :: * : * ***:*** ***.* : *.:: : . * :** .*. :*.:*::: *.*.: ::* * :*: .* *. : :. ::**: .: .*.", "identical_positions": 38, "similar_positions": 71, "identity": "10.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62662-1", "uniprot_id": "FRK_RAT", "id": "Q62662-1", "name": "Tyrosine-protein kinase FRK", "aln": "MG-----------SVCMRLWAYLQPFLPCW-------SQEADKSVVIENPGAYCPPEANRSQ------GQYFVALFDYEARTAEDLSFHAGDKLQVLDTSHEGWWLARHLEKKGPGLGQQLQGYIPSNYVAEDRSLQAEPWFFGAIKRADAEKQLLYSENQTGAFLIRESESQKGDFSLSVLDEGVVKHYRIRRLDEGGFFLTRRKTFSTLNEFVNYYTTTSDGLCVKLEKPCLKIQVPTPFDLSYKTVDQWEIDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKSLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQ--NDGGSKIRLTQQVDMAAQVASGMAYLESQNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNED-IYESKHEIKLPVKWTAPEAIRTNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIHMLGQNYRLPQPSNCPEQFYSIMMECWNVEPKQRPTFETLHWKLEDYFEPDS-SYSDTNNFIN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q922K9-1", "uniprot_id": "FRK_MOUSE", "id": "Q922K9-1", "name": "Tyrosine-protein kinase FRK", "aln": "MG-----------SVCVRLWAYLQPFLPCW-------SQEADKSVVIENPGAFCPPEAPRSQEPERSHGQYFVALFDYQARTAEDLSFRAGDKLQVLDTSHEGWWLARHLEKKGTGLGQQLQGYIPSNYVAEDRSLQAEPWFFGAIKRADAEKQLLYSENQTGAFLIRESESQKGDFSLSVLDEGVVKHYRIRRLDEGGFFLTRRKVFSTLNEFVNYYTTTSDGLCVKLEKPCLKIQVPTPFDLSYKTADQWEIDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKSLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQ--NDGGSKIHLIQQVDMAAQVASGMAYLESQNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNED-IYESKHEIKLPVKWTAPEAIRTNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLSQNYRLPQPSNCPQQFYSIMLECWNVEPKQRPTFETLHWKLEDYFETDC-SYSDTNNFIN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P42685-1", "uniprot_id": "FRK_HUMAN", "id": "P42685-1", "name": "Tyrosine-protein kinase FRK", "aln": "MS-----------NICQRLWEYLEPYLPCL-------STEADKSTVIENPGALCSPQSQRHG-------HYFVALFDYQARTAEDLSFRAGDKLQVLDTLHEGWWFARHLEKRRDGSSQQLQGYIPSNYVAEDRSLQAEPWFFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRIKRLDEGGFFLTRRRIFSTLNEFVSHYTKTSDGLCVKLGKPCLKIQVPAPFDLSYKTVDQWEIDRNSIQLLKRLGSGQFGEVWEGLWNNTTPVAVKTLKPGSMDPNDFLREAQIMKNLRHPKLIQLYAVCTLEDPIYIITELMRHGSLQEYLQ--NDTGSKIHLTQQVDMAAQVASGMAYLESRNYIHRDLAARNVLVGEHNIYKVADFGLARVFKVDNED-IYESRHEIKLPVKWTAPEAIRSNKFSIKSDVWSFGILLYEIITYGKMPYSGMTGAQVIQMLAQNYRLPQPSNCPQQFYNIMLECWNAEPKERPTFETLRWKLEDYFETDS-SYSDANNFIR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PC12-1", "uniprot_id": "A0A8M9PC12_DANRE", "id": "A0A8M9PC12-1", "name": "Tyrosine-protein kinase", "aln": "MG-----------DVRERIITCCQSVFQCFRDPDTSPSPDTGKRHIEVITNEFAKPQNRELP----PTPVLYVALYDYTARTDDDLSFNAGDKLEPITKGED-WWFSKAIT----GISANKKGYIPANYVAPVESLDAEPWYFPETKRSDAEKMLISQENKKGAFLIRNCESQPGELSLSVRDDVKVKHYKIRKLDNGGYYLSTARNFPTLRELVEHYSKHENGLCVCLAEPCKKSVAPETHGLSYNTVDQWEIERSSVKLLKQLGAGQFGEVFEGLWNDTTPVAVKTLKPGNMDPKDFLREAQIMKKLRHSKLIQLYAVCTLEEPIYIITELMSNGSLLEYLQ--NDRGATLRMSDQIDMGAQVASGMAYLELQNYIHRDLAARNVLVGDNNVCKVADFGLARVFQMDNEDNVYEAKEGTKFPVKWTAPEAINENKFTIKSDVWSFGILLYEIVTFGQTPYPTMTNFQVVQQLPKGYRMSSPPNCHKCLYDIMLDCWKDVPADRPTFETLQWKLEDFFDMDITSYDDANRFAK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V9J3-1", "uniprot_id": "SRC42_DROME", "id": "Q9V9J3-1", "name": "Tyrosine-protein kinase Src42A", "aln": "MGNCLTTQKGEPDKPADRIKLDDPPTIGVGVGVPQIPMPSHAGQPPEQIRPVPQIPESETAG----ANAKIFVALYDYDARTDEDLSFRKGEHLEILNDTQGDWWLARSKK-------TRSEGYIPSNYVAKLKSIEAEPWYFRKIKRIEAEKKLLLPENEHGAFLIRDSESRHNDYSLSVRDGDTVKHYRIRQLDEGGFFIARRTTFRTLQELVEHYSKDSDGLCVNLCKPCVQIEKPVTEGLSHRTRDQWEIDRTSLKFVRKLGSGQFGDVWEGLWNNTTPVAIKTLKSGTMDPKDFLAEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKMQTLIDMAAQIAAGMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLIK---ED-EYEARVGARFPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVEHGYRMPQPPNCEPRLYEIMLECWHKDPMRRPTFETLQWKLEDFYTSDQSDYKEAQAY--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . *: . : . *: :***:** *** :****. *::*: : . **::: . :****:**** .*::****:* * :*** *: **: *:****:.**: .: **** * ****:*::**:**:::: * **.*:*.:*:. .:**** * :** : * . .**:.* *****:*.*::::::**:****:*:*****:*****:****.*.***:*** ******.***.**********:*:********* :*** **** . * .::: :**.**:*:****** :***************: *: *:*******::: ** **:: ::*:******* . .**:************ *::*:*: **. **. :*: : :.**:..*.** :*.**::**: * *******:*****:: * .*.::: : ", "identical_positions": 244, "similar_positions": 131, "identity": "45.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-70", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VVV2-1", "uniprot_id": "OSTA_DROME", "id": "Q9VVV2-1", "name": "Organic solute transporter alpha-like protein", "aln": "MNASENYFTMDPTENISQVLDQNRNNTNSLRTHPTVEEYYENMTAFLSLAIFIASLLTILNISIFATTVSRLRRHLDKPLLGPSIMMVGLYPIISVAALVTILVPYSWFICHTVMHVMFMVGGPVFRTLLFRYVGSEQNYVKETAGEAVQLNTPPCCCCCLCLPMVIPTKAKLCISRYMVWQMPFWQGSIMLVMNILYYRDIQLYR------QVMFFFIPFIVCSIVLGAWSLQITVRMITKVRGDYQLRKKMFCLQLVVMLCKLQYLVLYDQLDGIKMGGEYPINHTVYKQTIINILILVEMVLVSMMVQSAYRTPVQVQIDEVNKEKEVTRI------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M6Z2F3-1", "uniprot_id": "A0A8M6Z2F3_DANRE", "id": "A0A8M6Z2F3-1", "name": "", "aln": "--------------------MRNRNCTLMGGGIPLSSEFFKVIKDDLWLFLLPAVFAVLLLALFLEEIGFFLRHVPSHRRKRLSLWILGVYPVFGMTSIISLYVPRSSSLCNFIASLYHSITLLKFMGLIKNFFGGNTRMLEALAGEQVSPNPFPCCCCC-CLPLFDINKTSVSWMMAAVLQLSVVR-TILFFLTLVLWTDEQYDYGDVNSVNLNMYVNAIIAISTFLSFYGYLLFYKATKRALPGHGLRAKFICIIVVLVLCGLQSGVLETMGALNVIPCTPPFSDLFRSQLIYHYSIIVEMFCISLFAHYTFRKVEPCQDVAEEMEVDVLRVFNEKSIQTEEELPIAVQLSSQEDDAFHSNLGYNSDSEDSSLCKIEHAPLDRFTFPSQHRMQTAANTEKVHTPPPEDSMRVKMPTITVSAQINHVDNGDVTVV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*** * * .*::: :. * * :: * : .:* :: **: .: *: ::*:**::.::::::: ** * :*: : : . : * *: .:.*.: . :: *** *. *. ****** ***:. .*:.:. * *:.. : :*::.:.:: : * * :: ::. .:*. * .*. :. : : .:. .: ** *::*: :*::** ** ** : *:.. . .* * : *:***. :*::.: ::*. * : * :* *: ", "identical_positions": 70, "similar_positions": 113, "identity": "16.06%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-71", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43025-1", "uniprot_id": "TETN_MOUSE", "id": "P43025-1", "name": "Tetranectin", "aln": "-MGFWG-TYLLFCLFS--------------------FLSQLTAESPTPKAKKAANAKKDLVSSKMFEELKNRMDVLAQEVALLKEKQALQTVCLKGTKVNLKCLLAFTQPKTFHEASEDCISQGGTLGTPQSELENEALFEYARHSVGNDANIWLGLNDMAAEGAWVDMTGGLLAYKNWETEITTQPDGGKAENCAALSGAANGKWFDKRCRDQLPYICQFAIV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05452-1", "uniprot_id": "TETN_HUMAN", "id": "P05452-1", "name": "Tetranectin", "aln": "-MELWG-AYLLLCLFS--------------------LLTQVTTEPPTQKPKKIVNAKKDVVNTKMFEELKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGIV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PDC0-1", "uniprot_id": "A0A8M9PDC0_DANRE", "id": "A0A8M9PDC0-1", "name": "", "aln": "MFGLICTSSVLLCMFFSTGCTYAEEKMDLKAVKFLLCVICLVKSSPEQSLTKRKNGKKE-SNSAAIEELKKQIDQIIQDLNLLKEQQALQTVCLKGFKIPGKCFLVDTVKKDFHSANDDCIAKGGILSTPMSGHENDQLQEYVQQTVGPETHIWLGVNDMIKEGEWIDLTGSPIRFKNWESEITHQPDGGRTHNCAVLSSTANGKWFDEDCRGEKASVCQFNIV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :*:*:* : :. ..* . .* *.**: .: :****.::* : *:: ****:********** *: **:*. * * **.*.:***::** *.** : **: * ** :::** ::.****:*** ** *:*:**. : :****:*** *****::.***.**.:*******: **.: . :*** **", "identical_positions": 96, "similar_positions": 60, "identity": "42.86%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-72", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6NGG8-1", "uniprot_id": "PCARE_HUMAN", "id": "A6NGG8-1", "name": "Photoreceptor cilium actin regulator", "aln": "MGCTPSHSDLVNSVAKSGIQFLKKPKAIRPGCQGGSERGSIPLLVKNSTCYDAGEGLAEEQPSPRRNQTTAKGLCQLMGDPASGKRKDMEGLIPGTKTSSSQLNKSQSHMAKDIPFKTQGSHGSQGADFSGDESEESSTQDTSKWKRTAKCHTSSTQSHCYQTIHPAHEPEGKVDFPEPLVKAHQQAYTYLHSSLSKYEAILCIIHQATQTRELLQPMVSFLLLCFEEISQLLGEISKDGEVLLQEVREDLAWPLKKREP----------QEQ-PNLLQQLLQYTVSKLQVLNGTVASLTGSFLEGSSSYLHSTATHLENKLSTKRNVDERLLRALRQLESLASGCGDPGVQGLPLCSEDSGIGADNESVQSVDKLGKQTSWDLAPEPEEWKSVTSPHTEARQSGHTWQQSPFCLGSGRPQDCLLSGAPMAKVQPRAQDEARSPCLSSTSPENITSPPLKLGTSTPCDSFGIGVSVEPHLSKTSRPMDASSLSDSEDSSPEEEEEDKMSSMSLCAWQEKTPHSRPQSSPADRESPFQARTRRLRSLQAQEMILKMKESISERIKFVPVPCGHQDWSEEEEGRTVVPPRPSTVSGSRRAPERQTRSQSESCLQSHVEDPTFQELRRVQRDLSQKLEAFYALGAKGQGQSQEQILQP-RAAAVWPNGTCRVSPSNTTSRLKASLTKNFSILPSQDKSILQKCNPHPEDEQ---GKAGKLPNAIPSGEVS-EAAKATDWNVRGCPTRTSVKKLIETFSPTESLRMLGDSKDAGASPCLRNC---IMPPRFPKYTGLAPLYPKPQISPASGRESLKMGIGWKPLAPIFPPLPKAEAAKSEELSCEMEGNLEHLPPPPMEVLMDKSFASLESPESSKSTENSPKETQEPGPGEAGPTRRTWASPKLRASVSPLDLLPSKSTASLTKPHSTGPGSGRSSCQPRKPALDLSSPPATSQSPEVKG--GTWSQAEKATSLYRQPRKAIAWHHSGPPSGQNRTSESSLARP----------RQSRERSPPVGRKASPTRTHWVPQADKRRRSLPSSYRPAQPSPSAVQTPPSPPVSPRVLSPPTTKRRTSPPHQPKLPNPPPESAPAQCKVPSPPTQHPEASPPFSIPSPSPPMSPSQEHKETRDSEDSQAVIAKVSGNTHSIFCPATSSLFEAKPPLSTAHPLTPPSLPPEAGGPLGNPAECWKNSSGPWLRADSQRRAALCALNPLPFLRRTASDRQPGGRPQPPTLDPTSTSYESQLGQNSSS----EESPKKDTEPGSSPCSPELQGG-TRRASPPEFCVLGHGLQPEPRTGHIQDKSQPEAQPQQEEVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6PAC4-1", "uniprot_id": "PCARE_MOUSE", "id": "Q6PAC4-1", "name": "Photoreceptor cilium actin regulator", "aln": "MGCTPSHNVIVNSVAKSGIQFFKKPKAILPGCQWGSPKCPIPLLVQSSTFCDSGGELHLGERLVEETVSSSK-KLQAMAEGVRQLPKAMEGLIP--ESQTFQVNKPQGHRATDISFRTEGSHGTQEVDFSGKESKENTPQETSKGNRESVCHQPDSQDHCRQS---ATESKGRVDFPEPLVKAHQHAYAYLHTSLSRYEAIVRLVQQASQTWGLLRPMLNFLLLCFEEAGQLLSEISKDGDVLLQEVRGDLAWPLRKGEP----------WEQHPDLLQQLLQYTVSKLRALHGTVAALTGSFLEGSSSCLRSTAGHLEGKLSTKRGIDECLLRALGQLESLTSSHGDAGLLGPPLCSEDSGIGADNESVHSVEKLGKQASWDFAAELGEWKPGTAAQVEARPSGHAWQEGPYWTGSDRPQDCPLSSPRIAKVQPAVQDEARSASTSGAGAEAVTSGPSEAAESLPWDSLGAEIPVRTPLSRSSGLTDAPSLSEEEDCSPEEEDE--LSSTDLHPEPQKALPSRPRSSPDTRESLFQPYSKELRNPQAQEMILKMKEAISERIKFVPEPSRPQDWTEEEEGGTVVPPRPRSVSGSRGGPERQRRSQSEGCLKSHVEDPTLQELRRVQTDLSRRLEVFYALGATRQGQSRERCLPS-RASVLWPPTNCRVSPSSAISKFKASLTQNFSILPNQDKSIFQKGSPCFDGEQPCQGKAEKLPNAIFCGKKSGRAPRDNERDIRACPTRPSVKTLIETFSPTESLRMPRNCRNLGSSPCLRKWGVPAMPPRFPIYRGLAPLYSKPQISPAAG---------WRPSAP-FPSLPLAEVSESEDISGDVEEDLENLPPPPLEVLMDKSFAALECPECSQPAGSSLEETLLPGLQEASHPKRTWVSPRLKASMSPMDLLPSKGSGSSPRLHSTRSGSTRIVGDSRKLTLDLNSKQTASPSSEAKSRAQIQARAETIAGFSKQHQKAIPWHHTNPTPGQSRTLEPSLARFSRDPHSSEASRKGPERSLPRVRKASPQRAQWASQGDRRLQSLPSSHGPSQPGLPAVLSSPSPPLSPRTLSPPATRKTTSPPCQHPQSNPAPG---------SPPVRRTETNTPSSASCSSPSVSPSRGSKDSIHSEDSEATTAKASRNTCSIFYPAATSLFEAKSSSSTSH----PQMLPEPGGLLRTPTGGWRGSSGQRLRADSQKRTVLNALNPLPFVRRTASDRQ---RQQGDQLQQSRSDWEFHSCQNSSSSSSSEENPKQELPPWNNSRVPELQGSSTKRASPLELCVLGHGLQPEARMNRGQDRPQPESQPQHKEIS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B6U4-1", "uniprot_id": "A0ACD6B6U4_DANRE", "id": "A0ACD6B6U4-1", "name": "", "aln": "MGCSPSK----------GQLFSKRP--ALPSGPAESKKNPDLLSDGDQIQSKAEDSEELAETEIEEPAKHSEGKRHSVDDVVCDATAIVR------------------EDAAEKILEIISSHDEQRAQETLLEQQEEAVEEKKTREKQVKRKKQRKPRLRKNS--------HVLAKAEFVLKAHQAAYAYLNPSISKYEALLGLLGQAAQTQRSLQTTVASVVLHFEEINQALEDLAADGEQLLREHGHNMTWPASFKDYPPTAANGQTGSPLPSELLQQMLLHSTVNMASMGDSVRCRSDSALQELAQYFGSMSELIGEKLLAKRAAEERLKQVLCHVEAAAFRK--PGPEDSALHSEDSGIGAENDCQNGSDRQ----------------------------------------------------------------RRSRGSSGSGANAGITSAFNNSASLDQQHASEPVSEE----------DEDDEEDDEDAEPEEEVS---GKDELEVQEDKKIETTYGFSEADTSR------------------PAFQGGLQEPAKASYLKRKIRRPKTADNNTLQMKPKHRHLRGPK-------RSQSAECLCSEEKDS------------DPHVKLGYQRNQHAQHWRRKNCLPEGRVRSKIRGGSSGAPSADRYYGLQYGSKGPFRAAPPSSPPTFTPEP----------------------------------------PGRNAVRRLINTFS--QGVEDSSRQRLLDQRPVRARG----------HKKCSLPLLQNSRAALTTG------------------------ADLHLLSDRPEILDLDSLPPPPPEMLMDSSYSSSAGPSAEE------------GPHEVQCRGQRTLTQRQPVPLSRANVQRCSISSSRPARQDAFLGS------------------------------------------------SIERDYTQVTEGENASLHT-----------------------------------------------------------KCYPPTTPPVSRTRLPPSCPSVHHAVPSPPSTTWPPNG-------------RWTPSAKPHTLP-------------------------------------PGSQSYLEARAKFCQEN----QPWPPSCTSTLPRPWG-----------DPARGRVSMGHLQPSGHCPQAHSEPLPDIRAQEGLIEDAS------------------DSTSDGTRP---ECEPEPADSHLNTLQPQQIAD------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:**: * * *:* *. * : . * .. .: : .. . :: : : : . :. . * : :. .**. * .: : *.:*.: ::... :: : . :: : .* ::**** **:**:.*:*:***:: :: **:** *:. : ::* *** .* * ::: **: **:* :::** : .:****:* ::. :: : .:* . :.* *: :. : * : : ** :** :* * :.* ::*: : .* . .* ********:*:. :. :: ** *.:..: : . : . * : . :. . * . .:.**..**** . .. .* :* : * . :: .:.* * : . ::. : *: : *.: **** ** *. :*. . ::: * . * ::. * *. .. ...:. :: . . * * .. . : * * :*: **:*** :.:. : . * . ** :.: : ::* . . :*: ***** *:***.*::: *...: * *. : : : ..:* :: .. :.* . :.: ** :* .:: . *:. : .. ...:**:* *.*. . : * . *. : . : * : . *.: * :**:. . : *. . * * :: *. : *:* . :: *: * * :: : :.... * ** .. . .* ::. ", "identical_positions": 167, "similar_positions": 287, "identity": "12.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-73", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UNY4-1", "uniprot_id": "TTF2_HUMAN", "id": "Q9UNY4-1", "name": "Transcription termination factor 2", "aln": "MEEVRCPEHGTFCFLKTGVRDGPNKGKSFYVCRA---DTCSFVRATDIPVSHCLLHEDFVVELQGLLLPQDKKEYRLFFRCIRSKAEGKRWCGSIPWQ-DPDSKEHSVSNKSQHASETFHHSSNWLRNPFKVLDKNQEPALWKQLIKGEGEEKKADKKQREKGDQLFDQKKEQKPE---MMEKDLSSGLVPKKKQSVVQEKKQEEGAEIQCEAETGGTHKRDFSEIKSQQCQGNELTRPSASSQEKSSGKSQDVQRESEPLREKVTQLLPQNVHSHNSISKPQKGGPLNKEYTNWEAKETKAKDGPSIQATQKSLPQGHFQERPETHSVPAPGGPAAQAAPAAPGLSLGEGREAATSSDDEEEDDVVFVSSKPGSPLLFDSTLDLETKENLQFPDRSVQRKVSPASGVSKK----VEPSDPVARRVYLTTQLKQKKSTLASVNIQALPDKGQKLIKQIQELEEVLSGLTLSPEQGTNEK--SNSQVPQQSHFTKTTTGP--PHLVPPQPLPRRGTQPVGSLELKSACQV-----TAGGSSQCYRGHTNQDHVHAVWKITSEAIGQLHRSLESCPGETVVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTQKNQEKKEEKEKSTALTWLSKDDSCDFTSHGTLIICPASLIHHWKNEVEKRVNSNKLRVYLYHGPNRDSRARVLSTYDIVITTYSLVAKEIPTNKQEAEIPGAN-LNVEGTSTPLLRIAWARIILDEAHNVKNPRVQTSIAVCKLQACARWAVTGTPIQNNLLDMYSLLKFLRCSPFDEFNLWRSQVDNGSKKGGERLSILTKSLLLRRTKDQLDSTGRPLVILPQRKFQLHHLKLSEDEETVYNVFFARSRSALQSYLKRHESRGNQSGRSPNNPFSRVALEFGSEEP-RHSEAADSPRSSTVHILSQLLRLRQCCCHLSLLKSALDPMELKGEGLVLSLEEQLSALTLSELRDSEPSSTVSLNGTFFKMELFEGMRESTKISSLLAELEAIQRNSASQKSVIVSQWTNMLKVVALHLKKHGLTYATIDGSVNPKQRMDLVEAFNHS-RGPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQQKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVLSGSGESVTKLTLADLRVLFGI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5NC05-1", "uniprot_id": "TTF2_MOUSE", "id": "Q5NC05-1", "name": "Transcription termination factor 2", "aln": "MDLVKCPEHGDACFLKTGVRDGPNKGKSFYVCRT---NTCGFVQATDIPVSHCLLHEEFVVELQGLFLPQDKKEWRLFFRCARTKAEGKQWCGNVPWRQDPNPKELSVTSKPQQPSESQLHSPSQPRNPFRVLNKNQKTLERKQFVE-EGERKTADKKLRENNEQLLDQRKEQKPKSNSRMEKDPSSDLVATRQSGGDREEQEKSKFQPKTKKAEG---------MASKQGHG-EVLQGIPKGPHMSESESRGVPNKPETLREKETQLLVPSVPGQNPESKVQKEGHVSRE-------PLKNGEAPSAQVTQRGLAQGPLQ-GPSKTWRPVP------EAPAAPELCSGMAHHATSSSEDSEDD---GVSSRPGSPLLFDSTVDSQKKGSLQHSDQSVQRQMPAASGVSKK----GDSSDPAAQRANLTTQLKQKKGTLAAVNIQALPDKGEKLLKQIQALEDALSALALSPEQGTKEK--CSAQEPEQSNITKAAAAP--LHLVPPQPLPRPLIQPASSLGLKAGRQE-----TPEGASQCSGGHMNQHHLYNVWKITSEAIDELHRSLKSCPGETAVAEDPAGLKVPLLLHQKQALAWLLWRESQKPQGGILADDMGLGKTLTMIALILTKKNQQKSKEKERSEPVTWLSKNDSSVFTSSGTLIVCPASLIHHWKNEVEKRVTSNRLRIYLYHGPNRSRHAKVLSTYDIVITTYSLLAKEIPTTKQEGEVPGAN-LSVEGTSAPLLQVVWARIILDEAHNVKNPRVQTSIAVCKLQAQARWAVTGTPIQNNLLDMYSLMKFLRCSPFDEFSLWKSQVDNGSMKGGERLSILTKSLLLRRTKDQLDSTGKPLVALPARRCQLHRLKLSEDERAVYDIFLARSRSALQSYLKRQEGRGSHHGRSPDNPFSRVAQEFGSSVS-QGCPAADSQRPSTVHVLSQLLRLRQCCCHLSLLKSALDPTELESEGLVLSLEEQLSALTLSKVDVSEPSPTVSLNGTCFKAELFDDTRRSTKVSSLLAELEAIQKGPGSQKSVIVSQWTSMLQVVALHLKKNRLTYATIDGSVNPKQRMDLVEAFNHS-QGPQVMLISLLAGGVGLNLTGGNHLFLLDMHWNPSLEDQACDRIYRVGQKKDVVIHRFVCEGTVEEKILQLQEKKKDLAKQVLSGSEGPVTKLTLADLKILFGI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IFG3-1", "uniprot_id": "A0A0R4IFG3_DANRE", "id": "A0A0R4IFG3-1", "name": "Transcription termination factor 2", "aln": "MERVLCERHGSTCLLKTGVKEGPNKGKSFYVCTARDATPCNFTLPTQIPASHCLQHEDSVVELQTLIYNKKQDKYKLFYRCMLGKTEGQKWCGCVPWK-EKDPDRQTDLLENLQSS-----SLTLVRNPFKVKIKQDKALKLRSDPDAEKDRGEVNDENKHANVQDNDKKRDERTG---TTEREGNNKKGPAVHSDTERRDSADSESWRNKTLPTG---------MKIKKRVSDDEKPKSAAEDETCPESSNPVKENDKGQTESENNLKDQQEQSPRKTGGSAQSPSKSSP-----GLDKKTSNKQSTSNSKSGSDKTQSQSPSCSTSQNGT------VSEKPTALDVQKIEPNQSKNKDQSGIACFGEWSDEDDDVLVIS-VQPPSQQSAPTPAVPVQKTITSYPGFQIASKVQGQSEDPRALHSQLKTQLKQKKATLSVVNVSALPDKGERLKRQVKDLEEALESLSLTAVSESQDKDRAEAEHKTAHSFSNPFSCPGGTILLPTAPAAMLKESSSASLGLNLSQGYSQMFGVNPQSQAFYGGRMTENRLLAVRNATTEAIDHLHDSLESCPTENTEAHDPKGLKVELLPHQKRALTWLLWRETQKPCGGILADDMGLGKTLTMIALILSQKKKDEKLEE-------WISKHGSSIVASQGTLIICPASLVHHWKKEIDKRVKSSRLTVYLYHGPNRQRSASVLAEHDVVITTYSLVSKEIPVQKEDAEKPSKDSDHVASDLPPLLRVAWARVILDEAHSIKNPKVQTSMAVCKLRARSRWAVTGTPIQNNLLDMYSLLKFLRCSPFDEYKLWKAQVDNGSKRGGERLNILTRALLLRRTKDQLDATGKPLVSLPDRTCEIHRLKLSEDEQAVYDVVFAQSRSTLQNYLKRHEDGNTKKG-DTSNPFEKVAREFGMSQQDSQSSSQQPQASSTIHILSLLLRLRQCCCHLSLLKKTLDQSELQGDGVALSLEEQLCALSLSEPSDSENKDTVSLNGSHFSSELFQDTRESTKISSILTELKEIRKK--DQKSVIVSQWTSMLKIVAVHLEKMGLKFAVIDGTVNPKRRMDLVEEFNTNPKGPQVMLVSLCAGGVGINLIGGNHLFLIDMHWNPALEDQACDRIYRVGQSKDVTIHRFVCDGTVEDKISSLQEKKKELAQKVLSGTGSSFTKLSLADLRVIFGV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * * .** *:*****::*********** : .*.*. .*:**.**** **: ***** *: :.:.:::**:** *:**::*** :**: : :... : : :.* * . ****:* *:::. :. . * :. .:.: :. . * *::::::. *:: .. . :.. :... .. : * : :: . : . . . .*. * .: : *. .:* . . . . : . * : * . :: . : * . . . : .. * . :...*.. * .. :*. * :: .: . . .**: :.. .*.. :..** * : *.*******.**: **:.******::* :*:: **:.*..*:*:. . :::* ..:: :::. : * *:*. * . .. .** *: . . :. *: .:.:: * : *:***..** **:*** *.. *.** **** ** ***:**:******:*** *********************::*::::. *: *:**..*. .:* ****:*****:****:*::***.*.:* :********. * **: :*:*******::****. *::.* *. : * . .***::.***:******.:***:****:*****:* :*******************:**********:.**::****** :*****.***::***********:**:*** ** * ::*:*******.:**::.:*:***:**.****:*. ..: * ...***.:** *** . . : :. .**:*:** ***************.:** **:.:*:.*******.**:**: ** . ******: *. ***:. *.***:**:*:**: *:: .**********.**::**:**:* *.:*.***:****:****** ** . :******:** *****:** *******:******:**************.***.******:****:** .******:**::****: ..***:****:::**:", "identical_positions": 515, "similar_positions": 340, "identity": "43.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-78", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A8MT69-1", "uniprot_id": "CENPX_HUMAN", "id": "A8MT69-1", "name": "Centromere protein X", "aln": "MEGAGAGSGFRKELVSRLLHLHFKDDKTKVSGDALQLMVELLKVFVVEAAVRGVRQAQAEDALRVDVDQLEKVLPQLLLDF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C4X1-1", "uniprot_id": "CENPX_MOUSE", "id": "Q8C4X1-1", "name": "Centromere protein X", "aln": "MEGN---SGFRKELVSRLLHLHFRDCKTKVSGDALQLMAEFLRIFVLEAAVRGVWQAQAEDLDVVEVDQLEKVLPQLLLDF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F1X6-1", "uniprot_id": "E7F1X6_DANRE", "id": "E7F1X6-1", "name": "Centromere protein X", "aln": "MATAGNEVAFKKETVAKLLSRSFREDKTRVSSDAVVLVAEMLKVFVEEATRRAIKQASSEDCDTVTIEHFEKILPQLLLDF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .*:** *::** *:: **:**.**: *:.*:*::** **: *.: **.:** * ::::**:********", "identical_positions": 37, "similar_positions": 24, "identity": "45.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-84", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z9I0-1", "uniprot_id": "D3Z9I0_RAT", "id": "D3Z9I0-1", "name": "", "aln": "-------------------------------------------------------MEPSRAP--------------------------ALRRLLPPLLLLLLPLYPRTRAKYVRGNLSSKEDWVFLTRFCF----LSDYGRLDFRFR--YPEAKCCQNILLYFDDPSQWPAVYKARDK-----------------------DCLAKESVIRPENNQVINLTTQYAWSGCQVVSEEGTRYLSCSSGRSFRSVRERWWYIALSKCGGDGLQ---------------LEYEMVLTNGKS------FWTRHFSADEFGILETDVTFLLIFTLIFVLSCYFGYLLKGRQLLHTTYKMFMAAAGVEVLSLLFFCIYWGQYATDGIGNDSVKILAKLLFSSSFLIFLLTLILLGKGFTVTRGRISHSGSVKLSVYMTLYTLTHVVLLIYEAEFFDPGQVLYTYESPAGYGLIGLQVAAYVWFCYAVLVSLR--HYPEKQPFYVPFFAAYTLWFFAVPVMALIANFGIPKWAREKIVNGIQLGIHLYAHGVFLIMTRPSAANKNFPYHVRTSQIASAGVPAPGGSQSADKAFPQHVYGNVTFISDSVPNFTELFSIPPPTSSAGKQVEETAVAAAVPPRGRVVTMAEPGAASPPPPARFPKAVDSGWDGPTPSYQPLVP------QTAAPHT------------------------------GFTEYFSMHTAGG-----------PAPPV----------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C4U2-1", "uniprot_id": "TM145_MOUSE", "id": "Q8C4U2-1", "name": "Transmembrane protein 145", "aln": "-------------------------------------------------------MEPSRAP--------------------------VLGRLLPPLLLLLLPLYPRTRAKYVRGNLSSKEDWVFLTRFCF----LSDYGRLDFRFR--YPEAKCCQNILLYFDDPSQWPAVYKARDK-----------------------DCLAKESVIRPENNQVINLTTQYAWSGCQVVSEEGTRYLSCSSGRSFRSVRERWWYIALSKCGGDGLQ---------------LEYEMVLTNGKS------FWTRHFSADEFGILETDVTFLLIFTLIFVLSCYFGYLLKGRQLLHTTYKMFMAAAGVEVLSLLFFCIYWGQYATDGIGNGSVKILAKLLFSSSFLIFLLTLILLGKGFTVTRGRISHSGSVKLSVYMTLYTLTHVVLLIYEAEFFDPGQVLYTYESPAGYGLIGLQVAAYVWFCYAVLVSLR--HYPEKQPFYVPFFAAYTLWFFAVPVMALIANFGIPKWAREKIVNGIQLGIHLYAHGVFLIMTRPSAANKNFPYHVRTSQIASAGVPGPGGSQSADKAFPQHVYGNVTFISDSVPNFTELFSIPPPTSSAGKQVEETAVAAAVAPRGRVVTMAEPGAASPPPPARFSKAVHSGWDGPTPSYQPLVPPEQRRGKPASPNTSACTQPGALHPRSEHPFPASAPRAAHRAPAGLRNPVSLPAQGLGHARHPAPLPHPAPTLDALRPAPFPLVPNGPAGAVLRVPSLSPCPEWLRNLDSRCSVISAPLTPFETSDPAGLRNTRDDRLDPARPSRTLRPSSHCLETDIVKLVSTLKPSLGFVTSDLCFVRPSECQGPSHGLWQKDVFSSCQNKEDSLSF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NBT3-1", "uniprot_id": "TM145_HUMAN", "id": "Q8NBT3-1", "name": "Transmembrane protein 145", "aln": "-------------------------------------------------------MEPLRAP--------------------------ALRRLLPPLLLLLLSLPPRARAKYVRGNLSSKEDWVFLTRFCF----LSDYGRLDFRFR--YPEAKCCQNILLYFDDPSQWPAVYKAGDK-----------------------DCLAKESVIRPENNQVINLTTQYAWSGCQVVSEEGTRYLSCSSGRSFRS--------------GDGLQ---------------LEYEMVLTNGKS------FWTRHFSADEFGILETDVTFLLIFILIFFLSCYFGYLLKGRQLLHTTYKMFMAAAGVEVLSLLFFCIYWGQYATDGIGNESVKILAKLLFSSSFLIFLLMLILLGKGFTVTRGRISHAGSVKLSVYMTLYTLTHVVLLIYEAEFFDPGQVLYTYESPAGYGLIGLQVAAYVWFCYAVLVSLR--HFPEKQPFYVPFFAAYTLWFFAVPVMALIANFGIPKWAREKIVNGIQLGIHLYAHGVFLIMTRPSAANKNFPYHVRTSQIASAGVPGPGGSQSADKAFPQHVYGNVTFISDSVPNFTELFSIPPPATSP-------------LPR-----------AAP--------------DSGLPLFRDLRP-------------------------------------------------------------------PGPLRDL--------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T776-1", "uniprot_id": "A0A8N7T776_DANRE", "id": "A0A8N7T776-1", "name": "", "aln": "------------------------------------------------------MRERGRASGSHSGQIFLCSHSIRRRAQKRYGGQVKMEKVLGLAVVSSMLCVGSVLGKYVKGIVNTKEDWVFLTRFCF----LTDFGRLNFRFR--YPKSRCCQNILLYFDESSQWPAVYKRPDK-----------------------DCYQKESVLRPENNQVINLTTRYTWSGCMVEGEGNEEMLSCVGGRSFRSVRERWWYIALSKCGGDGLQ---------------LEYEMTLTNGQS------FWTQHFSADEFGILETDITFLVIFATVFTLSCYFAYNLKARQLLHTTYKMFMTAAGVEVLSLLFFCIYWGLYARDGVGNGSLKILGKLLFSVSFLIFLLMLILLGKGFTVTRARISHSGSVKLSIYMTVYTITYIILFIYEAEFFDPGEVLYAYDSPAGYGLMGLQLLAYVWFCYAVLVSLK--HYPEKQPFYIPFFTAYTLWFFAVPVMALIANFGISRWAREKIVNGIQLGIHLYAHVVFLAITRPSAANKNFPYHVRTSQIG-ILLSSPKGMGAEN--FPHHAYGNSSFLGDSQPNFTELFSIHSDPVKT--------IDEAVTRKGQ---------EVPKNSEQKIITTTADLSSTFSSLPPPIP------PRSSAHS----------------------------------------------------PPPPPRLTSHFTEYFSMQGATGMGSNA--------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2B3-1", "uniprot_id": "Q9W2B3_DROME", "id": "Q9W2B3-1", "name": "GPR180/TMEM145 transmembrane domain-containing protein", "aln": "MHRCRFGITSDCGFVVWKFPQNKNKNRPRCANLQAMHKGAPPWRVGCADVASGMEWQLSGNPALGEEEEAANKQQQQQLIRSERWACNRRTILLGCICIIILIAVPSSNATHISGQFQTGDFFQFLAKFGFNKADLTRRNAYGYIYGNVTSTDKYAVPLTLVVLDRRTFLEFYGNRSQRSREAACTGMFSRLQRIAYDSTCNPRAKRDFLRHVPCPVNQLCSDEDEPGNVVPGSQFTYVINLEAEPRFWYLSLVACYQNKSTCQWHAHESLPRLSKLDSNLLNTLHYDIHLVNLHPNNSAAHPLTYQYSYDQQNLLEMYLVFLLVYIVLLPMQIYAVRRQK-----HPVTKLFTVSLLSEFVSLALITAHLIHYAANGVGEPRLQAAGDVLDILSRTTFMLILLLLAKGWAVTRQQISRTGWIILMSIWVPYCAFHVFLYIWDRTEVDVVSDIDEYQTWPGWIVLILRTSFMMWFLYELRNTMKYEHSTKKLDFLLHLGASSLVWFIYLPIVAIVALQVSPMWR-YKLLQGITNSADCMAYCVMTGLLWPHRAG-QYLLLAGTKYAGMDELDEFNEAPHIVRERERRRNSPPDEIAVGTGSRGMVLSTSIPHSLN---------------------------GDACNDLLEAEDLDAELLTDLNKNSHIVA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . :* : : ..:: * ..: : : **::* * *: . .: : . : . : * . : : .* .: : *...:* * :* : .* * .. :. . * .. : *.*:: *.* :. * ::* *: .:** :.**::: :: :. * * *.. *:* .: *.:** :: : ** :*:*: :: ..:* * *:* *:**.**::*** :**::* : * . * ::.* *:: .* . : *:: .*: :: *: :** * : ::: * .:* * : : :: :**: :*::*::* . * *:::** . . *: *: : * *. :: . *. . : :: . :. . . ::* . . ", "identical_positions": 83, "similar_positions": 155, "identity": "9.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110411-89", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91YX0-1", "uniprot_id": "THMS2_MOUSE", "id": "Q91YX0-1", "name": "Protein THEMIS2", "aln": "-MEPVPLQDFVSGLDPTSLPRVLRVCSGVYFEGSVYELFGNECCLSTGDLIKVTHVQLQKVVCEYPETGQTLELNPNFTGLFSPLTSLRSYRTLEDLVSAMPQ-NSTRWPIYFKSTQRIVTKASVVPEDQPLRLEAVEIHHG-IRYARCVQ--VSKTKELLHLPLSQKGPFWRCKPSAPQTLHQILQDP--ALKDLTLSCPSLPWNSVILKPQYMLQAIMHMRSSIVKIPSTLEVEVEDVTASSQHIHFFKPLRLSEVLAG-GGPFPLTTEILEVPEGPPVFLSPWVSFLRKGQRLCIYGPASPSWRVVASSKSRKVPRYFMLSGAYQGKLKRRPREFSTAYDLLGALQPGRPLRVVATKDCDGNEEENPDFSFLAVGDRLEVLRSGQVCGTK---GQDIDVLVCQRLSEQSGEEEEDLEEIEDEAEDKEQILLPLYLSGSFVEEVNDSRRYNLVDLTAQYSLPCEVKVVTKDTRHPTDPLASFPGLRLEEKLTEPFLVVSLDSQPEMCFEIPPRWLDLTVVEAEGQPAQVARP-LSIAPVEELSEAFYYSLRKLPASESQAPPPRPPKSQGINKKQQNIQSCKESSVKPQVVEPQKSCPQPQLKAKTLEALPKNKSNVYSKISVHKKD----RKPNPQTQNSVLSMKPKTSSSLGKHSTMESHLLPDPDMDDHDYEEI---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TEJ8-1", "uniprot_id": "THMS2_HUMAN", "id": "Q5TEJ8-1", "name": "Protein THEMIS2", "aln": "-MEPVPLQDFVRALDPASLPRVLRVCSGVYFEGSIYEISGNECCLSTGDLIKVTQVRLQKVVCENPKTSQTMELAPNFQGYFTPLNTPQSYETLEELVSATTQ-SSKQLPTCFMSTHRIVTEGRVVTEDQLLMLEAVVMHLG-IRSARCVLG-MEGQQVILHLPLSQKGPFWTWEPSAPRTLLQVLQDP--ALKDLVLTCPTLPWHSLILRPQYEIQAIMHMRRTIVKIPSTLEVDVEDVTASSRHVHFIKPLLLSEVLAW-EGPFPLSMEILEVPEGRPIFLSPWVGSLQKGQRLCVYGLASPPWRVLASSKGRKVPRHFLVSGGYQGKLRRRPREFPTAYDLLGAFQPGRPLRVVATKDCEGEREENPEFTSLAVGDRLEVLGPGQAHGAQ---GSDVDVLVCQRLSDQAGEDEE--EECKEEAESPERVLLPFHFPGSFVEEMSDSRRYSLADLTAQFSLPCEVKVVAKDTSHPTDPLTSFLGLRLEEKITEPFLVVSLDSEPGMCFEIPPRWLDLTVVKAKGQPDLPEGS-LPIATVEELTDTFYYRLRKLPACEIQAPPPRPPKNQGLSKQRR--HSSEGGVKSSQVLGLQQHARLPKPKAKTLPEFIKDGSSTYSKIPAHRKG----HRP----------AKPQRQ---------------DLDDDEHDYEEILEQFQKTI-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6D4-1", "uniprot_id": "A0ACD6B6D4_DANRE", "id": "A0ACD6B6D4-1", "name": "", "aln": "MGDLQSLQAFINCLDQRSLPRILQVCSGVYFQGSVYEISGSEVCLSTGDLVKIIGLELLSVSCEDVNTGDSFVLPIHYTGNFRLVAEDLPYNTVEELVGLCPVGVDACGSFTFRSTQELIVDNFTLAPDEHLTLLSVEVSEDGERLARCQVLGHNMAYAELLLPLSLKGEFYECEDERGYFLQEIMSSARLSCRRFCNTNTKSSGGLLMFSPVYEISAIMHLRKNIVKFPSTLEVDVQDVTDQFQDLVFITPLSLPEVVSQPKESFPTMAEILEAPEGNQYFSCSWFGGLQKGKSLILHECHQKTMILASTPKGKKGKQYFMISDDYGGRMRRRAREFGSVYELYLASSQSPGLKVSVSRDYEADEDEG--MPALGVGENLEVLGMSLMDRLKPGAAEKVESLICKRTHEVDDDDDD-------DEDDSEEISMPLFMAGHFVEKLSDNKKYRLNDLVSG-SLPVDVKVVTRDKDLEKDPLMGLPALKLEETFTETTVLTSLPHNPDWCFELPVRWLQMSVCFTSDDLPWSRPPELHVETVTEMTEKFYYEYHKLIG-KTEEPPPRPPKRKKSSCDANKKVQSLPSLGSSVSKQLDKLSLGPKVEKRSVPPPPQDEQTLHQPPPLLPRKSISLAESSSMPNMYVKSPRMSHKSGTFTDYIQILVVLNKMYTLTFSYLPLIKQRRDFLTRIMTTSLSRTHL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .** *: ** ****:*:*******:**:**: *.* *******:*: :.* .* ** :*.::: * :: * * : .*.*:*:**. . . . * **:.::.. .:. *: * * :* : . * *** . * **** ** *: : . * :::... : : : : .. . ::: * * :.****:* .***:******:*:*** . :.: *:.** *.**:: .** ****.*** * ..*.. *:**: * :: . . : ::.*.:* ::*::*. * *:::**.*** :.*:* * . . *:* .::* :.:.:*. :. *.**:.**** . : ...:: *:*:* : .:::: : :. *.: :*:.:.* ***::.*.::* * **.: *** :****::*. .*** .: .*:***.:**. ::.** :* ***:* ***:::* :..: . * : .* *::: *** :** . : : ******* : . . . .. . .. :: . *: : ::: :: .. :. . : .. : . . . ..* : ", "identical_positions": 189, "similar_positions": 227, "identity": "27.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110414-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTJ2-1", "uniprot_id": "D3ZTJ2_RAT", "id": "D3ZTJ2-1", "name": "Metallothionein", "aln": "MDPGECTCMSGGICICGDNCKCTTCSCKTCRKSCCPCCPPGCAKCARGCI--CKGGSDKCS--CCP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47945-1", "uniprot_id": "MT4_MOUSE", "id": "P47945-1", "name": "Metallothionein-4", "aln": "MDPGECTCMSGGICICGDNCKCTTCSCKTCRKSCCPCCPPGCAKCARGCI--CKGGSDKCS--CCP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IE87-1", "uniprot_id": "A0A0R4IE87_DANRE", "id": "A0A0R4IE87-1", "name": "Metallothionein", "aln": "MD--QCDCSKSGSCNCGDNCKCTNCSCAHDKKSCG-SCPSECSKGKKDCESACKDKEKSCTTHCCK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :* * ..* * ********.*** :*** .**. *:* :.* **. ...*: ** ", "identical_positions": 30, "similar_positions": 15, "identity": "45.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110418-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NCQ7-1", "uniprot_id": "PRCA1_HUMAN", "id": "Q8NCQ7-1", "name": "Protein PROCA1", "aln": "------------------------------------------------------------------------------------------------------MWVRTTLTIERWTKEKT----------EPKARSWDEALSDVNRLP------SWERGHLLAG---VASSTDVS--TFSEGGDCKEPDKCCWRHKQCTGHIIYPFASDCVRHSLHLHSVNHCNCNSRLKDSS--EDSSSSRGAGPTCSHVIESPCFELTPEEEHVERFRYGWCKSYRPVSVAVIHHPLYHECG-------------ADDLNEEEEEEEEESKPPIPTQVGPATASPDLGTSMATGTPDSTAPITIWRSESPTGK---GQGSKVIKKVKKKKEKEKDKEEMDEKAKLKKKAKKGQLTKKKSPVKLEPSPPDVSRSLSARQLARMSESSP-----------------------------------ESREELESEDSYNGRGQGE----LSSEDIVESSSPRKRENT--VQAKKTGAKPSQ-ARKVNKRKSPPGSNPNLS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B0QZF7-1", "uniprot_id": "PRCA1_MOUSE", "id": "B0QZF7-1", "name": "Protein PROCA1", "aln": "------------------------------------------------------------------------------------------------------MWVRTTITVKRWTEERS----------GRKIERTER--TDITRLP------SWKRGYPAS----VDSSSDLF--SFSEG-ENKETDRRCWKHQHCPGHTIHPFS-DCGHHNRCMHAVSQCDCESR---------------------------------------------CRSHRPVSVAIIYHPTHHMY-----------------MTDDDLEENWVSR---KNHLSPSARPPDPNTGSATEVPDLSVPITIWRSESPIEK---CQESNVIKDIKRKEKEQDEEEMVDEKANLKKKAK-GKLTKKKTPVKSESSPADLS--QSVRGPVRTPESSP-----------------------------------ESPGGLESEYSCE-RGKER----PSSEDVVESLSPRKKEKTSSGQAKKNGTKKET-QKTSKRKKSSPVPNPNLS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9Q5G7-1", "uniprot_id": "A0A8M9Q5G7_DANRE", "id": "A0A8M9Q5G7-1", "name": "phospholipase A2", "aln": "MWSVFFVFLSYLDRNFVKGEFLSQTLDAEKESKELFYMLNNTLCAKS-SVVGEYHLHQVTDGAEEVRSVHDSEGRLLDCSVIQNQMQVKSFMHVCRLGLRNQMSSDLKMSLTGVSEAKANCNKLRSKGAKNVIPTTKQVKEASNKKT------RTKRGFTYPGTLWCGAGNIAD--HYEQLGEFEETDRCCRVHDHCP-YVIHAFSSNYGYTNFKWHSLSHCDCDNALKECLRLVNDTSSRVVGQAFFNVIEVPCFEFSFEEQCVERHWYGVCKKYERVPVAVIKESIPYDFGGIDVIDVLTLAPLKGKQSDKEMQNKTESTTESTFPKTTSPEEPSLTNVVTAAEDFIKVLATVSTSQSSSTD---AGKGETQTSEKKKKKTSGKKKKENKKKRGKGKGRKKNKKLDAVLKVDEGASGATNPNEEVMGKNNYMEETPNTNQLSVKENNFMNSELDAVGNGALSNKMMRDDPQRSNDNRDADQSLVKTGKDPEILEYRQVNDTELVSPSPRDHITPASREKNRAKLRQRGGKKKQRKNNPSTEVSQAYFKEETLSVSAPEGASLATSTTESPITLEVTQSTQYTDEKGLVGTPVKSKTPRQREGRKRQRKVIASSNEELPRESTSEDPLLSTSTVEPTDLQERLGLDNLENAQQSSKDIKRGRRVIKICYEAVLPDVADTTPLPTLIEKDNEFQLKDPEVHTVIPNLQTNTPSMPPRRLGKTKVKRSRERGAGEKHGKVKRE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3I8-1", "uniprot_id": "Q9W3I8_DROME", "id": "Q9W3I8-1", "name": "phospholipase A2", "aln": "----------------------------------MWIANERTICALM-PLVILATWQLCLLPGTDAK----------------------------------HLAIRLRDPQSEIESETVPLAHVHSHSHTDESGVRGAAAVHRRERR------QLSDWLIAPNTRWCGRGNLANG-TYNDLGGASKADKCCRKHDHCK-MWIDGMSNRYDLFNYRPYTLSHCSCDLRFR------------------------------------------------------------------------------------------------TCLKMAGDEDAN---------AIGKLFFNVVQTQCFGLK---AETVCVQRGGSGKETDPCLKEEVRHKAFLRDNKRF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q6XPX3-1", "uniprot_id": "Q6XPX3_DROME", "id": "Q6XPX3-1", "name": "Phospholipase A2", "aln": "------------------------------------------------------------------------------------------------------MWLLREAFFFGLLAMAWAFG--------DEAIFEDEDIYNQALPP------VPHTGITVPGTKWCGPGNTAA--NFEDLGRERETDKCCRAHDHCDEIIESHGALHGLPTNTDWFPILKCTCEQQFIN------------------------------------------------------------------------------------------------CLQAVNSITAK---------TLGRIYYGSRSRCFANGH---PTTGCKQYQEGTFRKRCIRYQVDKSKAKVWQFYDMPFFTIPASAG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W4I0-1", "uniprot_id": "Q9W4I0_DROME", "id": "Q9W4I0-1", "name": "Phospholipase A2", "aln": "---------------------MREPLPVAVVTLLLFLWLGSAMPPTSGSAVLISDMTMSVMVELSSR----------------------------------HPFCKMHTDRGDIQRMLLQSDPRRIRQVPRESVMELEEVCRRQGSYGHEF--RGGLGFIYPGTKWCGPGTAAT--SYDDLGAHAREDRCCREHDMCP-DVLNVGECRRGLCNRGTFTRSHCDCDARFRR------------------------------------------------------------------------------------------------CLQAANTETAN---------TLGAIFYNVVQVTCFQERS--PCSAHQRFEDFYYRTDHCPAEFRQADLYVPPHGDNLIAKILAHPQGRALAAPSWTIPAKSTARRWG--------------------------------------VKLASVGLAAVNILREVVQRPRLLWDSLQAPVSRELPPPQRYHDPGYHYERPGPGSSYGYGQYSGRGYGGFDSPWS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VYG9-1", "uniprot_id": "Q9VYG9_DROME", "id": "Q9VYG9-1", "name": "Phospholipase A2", "aln": "-----------------------------------MRLIQNRWQEIGLQLIFVFNFGWIRRR---------------------------------------CFWVAAQSSRRCLSGSSSRSKKPRHTKMPYNLWLRRRLQLLASLLFCCLLGYLTSEAVAKPTLSFSLPQGLQGFPSFQSFTQQIIEQRSARQMKTYSGKRVSNDSLIMIYYHDLTIAVTELGPQKLLLG----------------------------------------------------------------------------------CELIEIYNDKEGKMLLEGLSHYNRPLEIKFDEMLKLMDQCEHVDKLSYASRHKSKLEGGERSNGGSASATTGGANDGVALKLATNIFPRSPFSLLSGIIPGTKWCGTGDIAETYSDLGSEMAMDRCCR------------------------------QHDLCPIKIRAYQNKYELMNDSLYTKSHCICDDMLFSCLKMTNTSASQLMGSIYFNLVQVPCLDGRSNHYKFRAAKEGF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.. :: . . . . : . . ", "identical_positions": 0, "similar_positions": 13, "identity": "0.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110419-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y534-1", "uniprot_id": "CSDC2_HUMAN", "id": "Q9Y534-1", "name": "Cold shock domain-containing protein C2", "aln": "MTSESTSPPVVPPLHSPKS-PVWPTFPFHREGSRVWERGGVPPRDLPSPLPTKRTRTYSATARASAGPVFKGVCKQFSRSQGHGFITPENGSEDIFVHVSDIEGEYVPVEGDEVTYKMCPIPPKNQKFQAVEVVLTQLAPHTPHETWSGQVVGS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2KDN7-1", "uniprot_id": "A0A0G2KDN7_DANRE", "id": "A0A0G2KDN7-1", "name": "", "aln": "MADPD------PALRSPRSAPLSLQFPFR---------SALPPKELPSPLPTKRTRTYSATVRANAGPVFKGVCKDFSRSQGHGFIKPAHGGDDIFFHISDIEGEYVPVEGDEVTYKVCLIPPKNVKVQAVEVTITHLKAGAKHETWSGQIIST", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:. . *.*:**:* *: ***: ..:**::****************.**.**********:**********.* :*.:***.*:******************:* ***** *.*****.:*:* . : *******::.:", "identical_positions": 95, "similar_positions": 33, "identity": "61.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110419-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q65Z95-1", "uniprot_id": "YPEL2_MOUSE", "id": "Q65Z95-1", "name": "Protein yippee-like 2", "aln": "-------MVKMTRSKTFQAY-------LPSCHR--------TYSCIHCRAHLANHDELISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIYCENCKTTLGWKYEHAFESSQKYKEGKYIIELAHMIKDNGWD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96QA6-1", "uniprot_id": "YPEL2_HUMAN", "id": "Q96QA6-1", "name": "Protein yippee-like 2", "aln": "-------MVKMTRSKTFQAY-------LPSCHR--------TYSCIHCRAHLANHDELISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIYCENCKTTLGWKYEHAFESSQKYKEGKYIIELAHMIKDNGWD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F3A4-1", "uniprot_id": "E7F3A4_DANRE", "id": "E7F3A4-1", "name": "Protein yippee-like", "aln": "-------MVTMTRSKTFQAY-------LPNCHR--------TYSCIHCRAHLANHDELISKSFQGSQGRAYLFNSVVNVGCGPAEERVLLTGLHAVADIYCENCKTTLGWKYEHAFESSQKYKEGKFIIELAHMIKDNGWD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2X7-1", "uniprot_id": "YPL1_DROME", "id": "Q9W2X7-1", "name": "Protein yippee-like", "aln": "-------MV-----KTFQAY-------LPSTNR--------TYSCVHCRAHLASHDELISKSFQGSQGPAYLFNSVVNVACGQTEERVLLTGLHAVADIYCECCKTPLGWKYEHAYESSQKYKEGKFIIELAHMIKENGWD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38191-1", "uniprot_id": "MOH1_YEAST", "id": "P38191-1", "name": "Pro-Apoptotic protein MOH1", "aln": "MGLRYSIYIENPLSSPSSSYKSINDPLFHSQHRSQKNVSFITYGCRHCKTHLSSSFQIISRDYRGRTGTAYLMNKVVNVVEGKVEQRRMLTGDYLVCDILCHWCKRNVGWKYLQSSNDDQQYKEGKFILELKNICKCT---", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. .:* : . :* **.* **::**:. ::**:.::* * ***:*.**** * .*:* :*** : *.** *. ** :**** :: :..*:*****:*:** :: * . ", "identical_positions": 47, "similar_positions": 39, "identity": "33.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110419-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P539-1", "uniprot_id": "F222B_MOUSE", "id": "Q6P539-1", "name": "Protein FAM222B", "aln": "MLACLPGPGDLSLQLLSHTQMNTGLQKWDTTQKMRTAHYPTPAELDAYAKKVANNPLTIKIFPNSVKVPQRKHVRRTVNGLDTSAQRYSPYPTQAATKAGLLAIVKVPAKSILKDFDGTRARFLPEAIMNPPVAPYATVAPSTLAH--PQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQ--------------------------PQGLGHPQQMAQTQGLVHPQALTH--------------QGLQHPPNPLLHGGRKMPDSDAPPNVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISRSLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAA-LPAAGPVN---LPTGISRAPTGYP----SDLKPVTWNQHQLAHLQQMCSEAGGTPAPGLTGKHTAGRELAGPGFVGKAAAYPQELCLAQSFHLKPPLEKPTPSPPVNGLPAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLTMPFHGGQPTGAPLDCGAAPGAHYRAGTGGGPVASQNSLMQTVDYLSGDFQQACFREQSLAMLSKAHRAPGTRAPDPTDSRSLHIQHPGYR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WU58-1", "uniprot_id": "F222B_HUMAN", "id": "Q8WU58-1", "name": "Protein FAM222B", "aln": "MLACLPGPGDLSFQLLSHTQMNTGLQKWDTTQKMRTAHYPTPAELDAYAKKVANNPLTIKIFPNSVKVPQRKHVRRTVNGLDTSAQRYSPYPTQAATKAGLLAIVKVPAKSILKDFDGTRARLLPEAIMNPPVAPYATVAPSTLAH--PQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQ--------------------------PQGLGHPQPMAQTQGLVHPQALAH--------------QGLQHPHNPLLHGGRKMPDSDAPPNVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISRSLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAA-LPAAGPVN---LPTGISRVPTGYP----SDLKPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAGPGFVGKAPAYPQELCLAQSFHLKPPLEKPTPSPPVNGMAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLAMPFHGGQPTGAPLDCAAAPGAHYRAGTGGGPVASQNSLMQTVDYLSGDFQQACFREQSLAMLSKAHRAPGNRAPDPTESRSLHIQHPGYR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F6C1-1", "uniprot_id": "E7F6C1_DANRE", "id": "E7F6C1-1", "name": "", "aln": "MLACLP-VSNPSLQLLSHTQMNTGLQKWDTTQRMRSAHYPTPAELDAYAKKVANNPLTIKIFPNSVKVPQRKHIRRTVNGLDTSSQRYSPYPPQVNTRTGLLAIVKVPVKGILKDIEGGRARFLPKLIMNPHSGLYANPSTLNVPHTVPHLQTPLGQKSLGHSQALQ-AHPQSLQQKSSLQPQQSLAHQEALHQSQAHQPPVPHHTLNHQQTLMQQQLSAPQGLRHLPDMAQSVNLQHSQGFSQSQPIPQASCAGPPASGVLQPPLAGLQMPRKLPDADAPPNVTVSTSTIPLSMAASLHQNRPSDLNSIVNQINQFCQARAGMGSTSVCEGQIANPSPISRNQLINASSRVCPHPTVGPPSSCILGNSDKGGPASALPLPDIAAMNRIPLYHNEMKQQQSQPQLPQQQRQQGPWGQHQLGHLQHLPEGAAHQ------GKNLPREGLMGPGFLTKNMGYPQEVCMAQPFNLKPPTDKPTPSPPVNGM--PVSYSNGHYMQPPWSNILPTPNSDSSGSQDLVGSFHGG-LSGASLDC--TPGAQYRTG---AALSSQTNLMQNMEYMGGDFQTPCFRAQNPGTMAKMHRTPVNRATDSGDSRNVHIHHPGYR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****** .: *:*******************:**:*************************************:**********:*******.*. *::*********.*.****::* ***:**: **** . **. :. .:.* *: *: *::* *:*:* * **:**: ..: * *:*:* ::*:* **** * ***: .* *.*.::: .*: :* . *: **:**:*******************:*::.:*.**.***:*******:***:.:****************. *****:**..*.. * .**::. :: .*:* ** ..:* * . : . * .: : .*.****.***:: . *. **: . . * ****: * .****:*:**.*:**** :**********: *::*.****:** *.****************. .**** :**.*** :***:**:* ..::**..***.::*:.**** .*** *. . ::* **:* .**.*. :**.:**:*****", "identical_positions": 326, "similar_positions": 143, "identity": "53.27%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110419-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IS24-1", "uniprot_id": "GLT17_HUMAN", "id": "Q6IS24-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 17", "aln": "--------------MASLRRVKVLLVLNLIAVAGFVLFLAKCRPIAVRSGDAFHEIRPRAEV-ANLSAHSASPIQDAVLKRLSLLEDIVYRQLNGLSKSLGLIEGYGGRGKGGLPATLSPAEEEKAKGPHEKYGYNSYLSEKISLDRSIPDYRPTKCKELKYSKDLPQISIIFIFVNEALSVILRSVHSAVNHTPTHLLKEIILVDDNSDEEELKVPLEEYVHKRYPGLVKVVRNQKREGLIRARIEGWKVATGQVTGFFDAHVEFTAGWAEPVLSRIQENRKRVILPSIDNIKQDNFEVQRYENSAHGYSWELWCMYISPPKDWWDAGDPSLPIRTPAMIGCSFVVNRKFFGEIGLLDPGMDVYGGENIELGIKVWLCGGSMEVLPCSRVAHIERKKKPYNSNIGFYTKRNALRVAEVWMDDYKSHVYIAWNLPLENPGIDIGDVSERRALRKSLKCKNFQWYLDHVYPEMRRYNNTVAYGELRNNKAKDVCLDQGPLENHTAILYPCHGWGPQLARYTKEGFLHLGALGTTTLLPDTRCLVDNSKSRLPQLLDCDKVKSSLYKRWNFIQNGAIMNKGTGRCLEVE-NRGLAGIDLILRSCTGQRWTIKNSIK-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TT15-1", "uniprot_id": "GLT17_MOUSE", "id": "Q7TT15-1", "name": "Polypeptide N-acetylgalactosaminyltransferase 17", "aln": "--------------MASLRRVKVLLVLNLIAVAGFVIFLAKCRPIAVRSGDAFHEIRPRAEV-ANLSAHSASPIQDAVLKRLSLLEDIVYRQLNGLSKSLGLIEGYGGRGKGGLPATLSPSEEEKAKGPHEKYGYNSYLSEKISLDRSIPDYRPTKCKELKYSKELPQISIIFIFVNEALSVILRSVHSAVNHTPTHLLKEIILVDDNSDEEELKAPLEEYVHKRYPGLVKVVRNQKREGLIRARIEGWKAATGQVTGFFDAHVEFTAGWAEPVLSRIQENRKRVILPSIDNIKQDNFEVQRYENSAHGYSWELWCMYISPPKDWWDAGDPSLPIRTPAMIGCSFVVNRKFFGEIGLLDPGMDVYGGENIELGIKVWLCGGSMEVLPCSRVAHIERKKKPYNSNIGFYTKRNALRVAEVWMDDYKSHVYIAWNLPLENPGIDIGDVSERKALRKSLKCKNFQWYLDHVYPEMRRYNNTIAYGELRNNKAKDVCLDQGPLENHTAILYPCHGWGPQLARYTKEGFLHLGALGTTTLLPDTRCLVDNSKSRLPQLLDCDKVKSSLYKRWNFIQNGAIMNKGTGRCLEVE-NRGLAGIDLILRSCTGQRWAIKNPIK-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7EZL6-1", "uniprot_id": "E7EZL6_DANRE", "id": "E7EZL6-1", "name": "Polypeptide N-acetylgalactosaminyltransferase", "aln": "MMRFTGFRTPKSFMAFVMRRWKILLVLNVFTVAGFITFWGKCNVRTTKGVGQQMAVDSRGQTNLNGSVQETSITHDVLLKRLGSLEDVVYRQLNGLSKSLGLIEGFGGRGRGGIPATLTPAEEKEAKFLREKYGYNAFLSDKISLDRSLPDYRPSKCKKAFFPRDLPQISIIFIFVNEALSVILRSVHSAVNHTPAHLLKEIILVDDNSDDVQLKGPLEEYVNKRYPGLIKIVRNQKREGLIRARIEGWKVATGEVTGFFDAHVEFTPAWAEPVLSRIKENHKRIILPSIDNIKDETFELERYENSGHGYNWELWCMYISPPKQWWDEGDTSAPIRTPAMIGCSFVVNREYFGDLGLLDAGMDVYGGENIELGIRVWLCGGSMEVLPCSRVAHIARTKKPYHSNIAFHTRRNALRVAEVWMDQYKSNVYLAWNLPMKNHGIDYGDVSERLALRKRLQCKSFDWYLDNIYPEMRRYNNTVFYGEIRNTNVTHLCVDQGIKENHTATLHPCHGWGPQLGRYTKEGYLFLGPLGSTG--EDTRCVVDDKISSYPQLLNCEKVSSVRQKTWHFAQNESIISRATGRCLEVVPANVYFGYALILRSCTGQKWNIKNLMKQDQGQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :** *:*****:::****: * .**. :.:. . : .*.:. * *.:.:* :*.:****. ***:*****************:****:**:****:*:**::** :******::**:*******:*****:***: :.::******************************:**************: :** ******:******:*:******************.***:************..*********:**:**:*********::.**::*****.***.************:*** **.* ****************::**::****.**************:******************* *.****:***.*:*:************:***:**:*****::* *** ****** **** *:**.*:****::**********: ***:**.:...:*:*** ***** *:*********.******:*.**.**:* ****:**:. * ****:*:**.* * *:* ** :*:.:.******* . * *********:* *** :* ", "identical_positions": 422, "similar_positions": 118, "identity": "68.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110420-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43490-1", "uniprot_id": "NAMPT_HUMAN", "id": "P43490-1", "name": "Nicotinamide phosphoribosyltransferase", "aln": "-MNPAAEAEFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKTENSKLRKVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKDVYKEHFQDDVFNEKGWNYILEKYDGHLPIEIKAVPEGFVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGLALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTQAPLIIRPDSGNPLDTVLKVLEILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKMWSIENIAFGSGGGLLQKLTRDLLNCSFKCSYVVTNGLGINVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGQDLLHTVFKNGKVTKSYSFDEIRKNAQLNIELEAAHH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99KQ4-1", "uniprot_id": "NAMPT_MOUSE", "id": "Q99KQ4-1", "name": "Nicotinamide phosphoribosyltransferase", "aln": "-MNAAAEAEFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKTENSKVRKVKYEETVFYGLQYILNKYLKGKVVTKEKIQEAKEVYREHFQDDVFNERGWNYILEKYDGHLPIEVKAVPEGSVIPRGNVLFTVENTDPECYWLTNWIETILVQSWYPITVATNSREQKKILAKYLLETSGNLDGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGIALIKKYYGTKDPVPGYSVPAAEHSTITAWGKDHEKDAFEHIVTQFSSVPVSVVSDSYDIYNACEKIWGEDLRHLIVSRSTEAPLIIRPDSGNPLDTVLKVLDILGKKFPVTENSKGYKLLPPYLRVIQGDGVDINTLQEIVEGMKQKKWSIENVSFGSGGALLQKLTRDLLNCSFKCSYVVTNGLGVNVFKDPVADPNKRSKKGRLSLHRTPAGNFVTLEEGKGDLEEYGHDLLHTVFKNGKVTKSYSFDEVRKNAQLNIEQDVAPH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F8T6-1", "uniprot_id": "E7F8T6_DANRE", "id": "E7F8T6-1", "name": "Nicotinamide phosphoribosyltransferase", "aln": "MEKHREAADFNILLATDSYKVTHYKQYPPNTSKVYSYFECREKKTDSTKPRKVKYDKTVFYGLQYILHKYLKGQVITPEKIQEAKEVYREHFQDDVFNEKGWNYILEKYNGHLPIEIKAVPEGSVIPRGNVLFTVENTDPECYWLTNWVETCLVQIWYPITVATNSREQKKILAKYLMETSGSLEGLEYKLHDFGYRGVSSQETAGIGASAHLVNFKGTDTVAGIGVIKKYYGTKDPVPGFSVPAAEHSTITAWGKDHEKDAFEHIIKQFPSVPVSIVSDSYDIYNACEKIWGEDLRSLIEMRSADAPLVVRPDSGNPLDTVLKVLEILGKKFPPEENSKGYKVLPPYIRVIQGDGVDINTLQEIVEGMKEHRWSIENIAFGSGGALLQKLTRDLLNCSFKCSYVVTNGLGVNVFKDPVADPNKRSKKGRLSLHRTPSGDFVTLEEGKGDLEEYGEDLLHTVFRNGKIVKTYTFDEVRDNAKLK-ESEVQDLLL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *:************************************:.:* *****::**********:*****:*:* *******:**:**********:*********:******:****** ************************:** *** *********************:****.*:***************************************:.:*************:*************************:.**.*****:******************** ** **::***::***************:******* *******:****:*********************:: *****::*****.*************************:*************************:*:***************.*******:***:.*:*:***:*.**:*: * :. ", "identical_positions": 416, "similar_positions": 54, "identity": "84.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110420-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q16563-1", "uniprot_id": "SYPL1_HUMAN", "id": "Q16563-1", "name": "Synaptophysin-like protein 1", "aln": "MAPNIYLVRQRISRLGQRMSGFQINLNPLKEPLGFIKVLEWIASIFAFATCGGFKGQTEIQVNCPPA-VTENKTVTATFGYPFRLNEASFQPPPGVNICDVNWKDYVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTSLYLDSRKLPMIDFVVTLVATFLWLVSTSAWAKALTDIKIATGHN-IIDELPPCK-KKAVLCYFGSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSAPHSQGGIPPPTGI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O09117-1", "uniprot_id": "SYPL1_MOUSE", "id": "O09117-1", "name": "Synaptophysin-like protein 1", "aln": "MASKANMVRQRFSRLSQRMSAFQINLNPLKEPLGFIKILEWFASIFAFATCGGFKGKTEIQVNCPKVGVNKNQTVTATFGYPFRLNQASFHTPPNVSVCDVNWEKHVLIGDYSSSAQFYVTFAVFVFLYCIAALLLYVGYTNLYRDSRKLPMIDFIVTLVATFLWLVSSSAWAKALTDIKVATGHR-IVEELEICNPESGVSCYFVSVTSMGSLNVSVIFGFLNMILWGGNAWFVYKETSLHSPSNTSASHSQGGGPPTSGM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "X1WHJ9-1", "uniprot_id": "X1WHJ9_DANRE", "id": "X1WHJ9-1", "name": "", "aln": "-----------------MQTGFRLNLSPVKEPLGFVKVLEWITAVLAFGTCGGFSGRNVLSVFCDGS----NETLTATFTYPFRLNHELLVEQ-NRTLCNRSVSATHLVGDSSSSVEFFVAVAVLAFLYSMLALIVYLGYMHVYRDSDFGPMFDFVLTAVFAFLWLVCSSAWARGLQTVKDATSTAGMESTLALCK-DRGVRCEVTEFASMRSLNISVVFGFLNLIIWAGNAWFVYKETRWHS-QKVNAQQTPGRAPAPAPI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*::**.*:******:*:***:::::**.*****.*:. :.* * *:*:**** ******. : . .:*: . . *:** ***.:*:*:.**:.***.: **::*:** :* ** **:**::* * :*****.:****:.* :* **. : . * *: . .* * . ..:** ***:**:*****:*:*.********** ** .:..* :: * *..: :", "identical_positions": 110, "similar_positions": 77, "identity": "41.98%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110420-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q16534-1", "uniprot_id": "HLF_HUMAN", "id": "Q16534-1", "name": "Hepatic leukemia factor", "aln": "MEKMSRPLPLNPTFIPPP-YGVLRSLLENPLKLPLHHEDAFSKDKDKEKKLDDESNSPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPPGLQPASS----------AAP----SVMDLSSRASAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLK-DDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BW74-1", "uniprot_id": "HLF_MOUSE", "id": "Q8BW74-1", "name": "Hepatic leukemia factor", "aln": "MEKMSRQLPLNPTFIPPP-YGVLRSLLENPLKLPLHPEDAFSKEKDKGKKLDDESSSPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPPGLQPASS----------TAP----SVMDLSSRATAPLHPGIPSPNCMQSPIRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLK-DDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LSP0-1", "uniprot_id": "A0ABK0LSP0_RAT", "id": "A0ABK0LSP0-1", "name": "", "aln": "MEKMSRQLPLNPTFIPPP-YGVLRSLLENPLKLPLHPEDAFSKDRDKGKKLDDGSNSPTVPQSAFLGPTLWDKTLPYDGDTFQLEYMDLEEFLSENGIPPSPSQHDHSPHPPGLQPASS----------TAP----SVMDLSSRATAPLHPGIPSPNCMQNPIRPGQLLPANRNTPSPIDPDTIQVPVGYEPDPADLALSSIPGQEMFDPRKRKFSEEELKPQPMIKKARKVFIPDDLKQDDKYWARRRKNNMAAKRSRDARRLKENQIAIRASFLEKENSALRQEVADLRKELGKCKNILAKYEARHGPL-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M2B317-1", "uniprot_id": "A0A8M2B317_DANRE", "id": "A0A8M2B317-1", "name": "", "aln": "---MSRQLTMNPAFLPPQTNGVLKALLEKPLKLPLHQDEGYGKERDKVKKLDEEGNP---PQSAFLGPTLWDKTLSYDGDSFQLEYMDLEEFLSENGIPSSPAQHDQNLHQHHHQQQQQQQHQQQQQQVSMPQGPISVMDLSSRS---IHTAISPQNCLHSPGRS--VLPPSRNTPSPVDPEALHIPVSYEPDPADLALSSVPGQEVFDPRKRKFSEEELKPQPMIKKARKIFIPDDLKQDEKYWARRRKNNVAAKRSRDARRLKENQIAIRAGFLEKENMALRQEVADLRKELGRCKNILTKYEAQHGPL-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1ZAC2-1", "uniprot_id": "A1ZAC2_DROME", "id": "A1ZAC2-1", "name": "BZIP domain-containing protein", "aln": "--------------MHSP---AQSPILDVTETVSMHS--------------------------------------------------ELDAELESKNNPSYSISIPQNLRLTGLGFP----------------------------------------GMIGAKRSSETLPAFEYIAPPS-----HALQALEFPLMELNRVGVIGGGMFPGFVHRRVRGEKRP-----------IPEAQK-DAKYFERRKRNNEAAKRSRDARKIREDRIAFRAALLEQENSILRAQVLALRDELQTVRQLLGATTAGGMLSMARQV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . .:*: . .:.:* :*: *..:. *. . . :. : : .. *. **. . ..* : . * :* .: * :* :: . * :* **: * * **: **::** *********:::*::**:**.:**:** ** :* **.** :::* * ", "identical_positions": 52, "similar_positions": 59, "identity": "16.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110420-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LS06-1", "uniprot_id": "A0ABK0LS06_RAT", "id": "A0ABK0LS06-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MDIGTSSARSSSPLERDP-----------------------AFRVITVAKETGLGLKILGGIDRNEGPLVYIHEVTPGGDCYKDGRLKPGDQLVSINKESMIGVSFEEAKNILTRAKLRWESPLEIAFIRQKSYCGH---PGNICCQS-PPVSEDCEPQTSAFNLL-SSPAGTLLPKTSSTPRTQDSILPSCTVIQTQPEHSQAGLAPVPSLNNRPTDTSNADIAPAWTDDASGPQGKISLNPSARLKAEKLEMALNYLGIQPTKEQHEALRQQVQADSEGTVSFGDFVQVARNLFCL--QLD-EVNVGDHELPSVLDSQLLPCGSL----EADEVGRLRQERNAALEERDALKEKLLESEKHRKQLIEELQNVKQEAKAVAEETRALRSRIHLAEAAQRQARGMEMDYEEVIRLLEAEVSELKARLADYSDQNKESVQDLRKRVTVLDCQLRKSEMARKTFKSSTERLLRFVEAIQEVLLDSCAPLSNLSERRAVLASQTSLPLLGRNGRNFP---APLLLESKELLRSVRAVLDMDCLPYGWEEAYTADGIKYFINHVTQTTSWIHPMMSVLNLSCAEESEEDCPRELREPKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WV89-1", "uniprot_id": "STXB4_MOUSE", "id": "Q9WV89-1", "name": "Syntaxin-binding protein 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MSDGTASARSSSPLDRDP-----------------------AFRVITVTKETGLGLKILGGINRNEGPLVYIHEVIPGGDCYKDGRLKPGDQLVSINKESMIGVSFEEAKSIITRAKLRSESPWEIAFIRQKSYCGH---PGNICCPS-PQVSEDCGPQTSTFTLL-SSPSETLLPKTSSTPQTQDSTFPSCKAIQTKPEHDKTEHSPITSLDNSPADTSNADIAPAWTDDDSGPQGKISLNPSVRLKAEKLEMALNYLGIQPTKEQREALREQVQADSKGTVSFGDFVQVARSLFCL--QLD-EVNVGVHEIPSILDSQLLPCDSL----EADEVGKLRQERNAALEERNVLKEKLLESEKHRKQLIEELQNVKQEAKAVAEETRALRSRIHLAEAAQRQAHGMEMDYEEVIRLLEAEVSELKAQLADYSDQNKESVQDLRKRVTVLDCQLRKSEMARKAFKASTERLLGFIEAIQEVLLDSSAPLSTLSERRAVLASQTSLPLLARNGRSFP---ATLLLESKELVRSVRAILDMDCLPYGWEEAYTADGIKYFINHVTQTTSWIHPVMSALNLSCAEESEEDCPRELTDPKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZWJ1-1", "uniprot_id": "STXB4_HUMAN", "id": "Q6ZWJ1-1", "name": "Syntaxin-binding protein 4", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MNKNTSTVVSPSLLEKDP-----------------------AFQMITIAKETGLGLKVLGGINRNEGPLVYIQEIIPGGDCYKDGRLKPGDQLVSVNKESMIGVSFEEAKSIITGAKLRLESAWEIAFIRQKSDNIQ---PENLSCTSLIEASGEYGPQASTLSLF-SSPPEILIPKTSSTPKTNNDILSSC---EIKTGYNKTVQIPITSE-NSTVGLSNTDVASAWTEN-YGLQEKISLNPSVRFKAEKLEMALNYLGIQPTKEQHQALRQQVQADSKGTVSFGDFVQVARNLFCL--QLD-EVNVGAHEISNILDSQLLPCDSS----EADEMERLKCERDDALKEVNTLKEKLLESDKQRKQLTEELQNVKQEAKAVVEETRALRSRIHLAEAAQRQAHGMEMDYEEVIRLLEAKITELKAQLADYSDQNKESVQDLKKRIMVLDCQLRKSEMARKTFEASTEKLLHFVEAIQEVFSDNSTPLSNLSERRAVLASQTSLTPLGRNGRSIP---ATLALESKELVKSVRALLDMDCLPYGWEEAYTADGIKYFINHVTQTTSWIHPVMSVLNLSRSEENEEDCSRELPNQKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B4S3-1", "uniprot_id": "A0A8M3B4S3_DANRE", "id": "A0A8M3B4S3-1", "name": "", "aln": "MALLPQSVEAEHFDGLSLLYWTIMGPHGINRAVERLEFTDCKKGLGVKIIGGYRGQSGEEFGIFIKRILPGGVAAQDGRLRPGDLILDVNNMNLRGVTNEKAVEVLRMASATNHMSLLVVRDDASRREFTELMEKYGSSSSTSSGSDTSVSTGKMTDTASSSSSSRSTSPLLLSPKEPSPVYTTACINSPSPQVCTDCMIQLICVAKGTGLGLVIRGGANRAEGPMVFVQEIIQGGDCQKDGRLKSGDQLISINKESLVGVTHEEAKSILTRTKLRPDPTVEIAFIRRRSSSGSSSGPHSPISLQPSCSTNHPAPQTKPSGLSGAALPGGLVPKIANTPNSGSETLPSVELTKVRAATGKPVLAPVTSPESACTTVANADASAACNPS--RPSKPLCSVQSFELKPEKIDQTLEVLGLKPADSQVLTLRERLRLNAGGTVAYGDFDTVTKELFKQPSKLDSEQEVARLTSDDLIESPSNPTPSLSDSDDLDEMERLRKEHIEALRELKGLQDKLAESESLNHKMLQELTKVKQDAKSAVEESRSLRTRIHLAEAAQKQARGMEMDYEEVIHLLEAEIAEMKSLKTEQPSQEKEDLQDLKKRISVLECQLRKSEVAKKGFQVSTGKLLQFVEAVQSFLSENPSASRGHSSHYDVKSGTLSQTVASRGVKKTPCTASSLSVEAKELTQTVRSILELDCLPFGWDEAYTSDGVKYYINHVTQTTSWTHPVTRSLGLS-DPGTSDHPTLDSPEFTA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::: *.* * .* :::* ::* ***** : ** :* ***:*:::*: **** ******.****:*:****::**:.****.*:* :*** :.. ******::* * . . . : . **:.. * :: . *:** :.**.: .. :.* : :. .:. *:.* . . :*:* :.* . . . :. * .:*.**:: :*: **::*:..* :**:::: :: ***::*** *::.** :** * :*. .:::* * * : **: :*: *: **.* . *::** **:. .::: :** :***:**:..**:*:**:*********:**:**********:****:::*:*: :: ..*:**.:***:**: **:*******:*:* *: ** :** *:**:*..: :. :. *.: * :. * . .*. :. * :.* :*:*** ::**::*::****:**:****:**:**:********** **: *.** ..:. . : : .:", "identical_positions": 219, "similar_positions": 193, "identity": "29.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110421-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NA54-1", "uniprot_id": "IQUB_HUMAN", "id": "Q8NA54-1", "name": "IQ motif and ubiquitin-like domain-containing protein", "aln": "MSNQQEKYEAQNIVNSTEESDDAFDTVTIPVPSEEP-QESDQTEEHESGIEQFSESHAIHVEEQSDQSFSSLEPDNEQLMEEVISPRQVSYTPQHHEKQYAMQRPNDDSLAFLDKIKSVKESLQESVEDSLATVKVVLIPVGQEIVIPFKVDTILKYLKDHFSHLLGIPHSVLQIRYSGKILKNNETLVQHGVKPQEIVQVEIFSTNPDLYPVRRIDGLTDV--SQIITVTVQTGLDQYQQVPVEIVKSDFHKPFLGGFRHKVTGVEYHNAGTQTVPKRIPER-LSIFCRDTQTVFQKKN-LQQTTNTTSTQMTNIGVYVSNMTDKLVTPGKYFSAAEYHAQRLKAVIVIQTYYRQWHAKIFVENLRRQKSLRLEWETQQELRKIREKEEWIKLDYHRRHNPKTNEDFEFLYNALEFWRQEELTRINQSFTGAERKAALCELLEKETQIIASIGRHRYIAYMANQEAAIQAFLDKCSAPKIWRTPNGKTIEMDTQFTIRARELQNIYKCIMLKNISQDERLDVLLTLKHTVKEHECKLTQEILELIDREVDLMMRGVKHHNLEGLRKRIATLFFHYIKTPLFNPEVAKYLKVPQDPLKFYKKIYFCHSCQLYLPSTEFSVSSTSRRIYRCRNCINLQNEAQKRESFLKYKCLLQQLYYTEADYEDDSKIAFLMQLQDIQYLTENIWASQSVLSACDNLSDLVMVRWNKSLEWSPWNCILLTKDEAAAHLKLTSIEEGYERSFIHKIKHKHILAKNYFSQVPVLASFILDDGEIDEIRWKYHSDTTPKIIESQR-PPH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CDK3-1", "uniprot_id": "IQUB_MOUSE", "id": "Q8CDK3-1", "name": "IQ motif and ubiquitin-like domain-containing protein", "aln": "MSDPEE----ERVADSTAHYEEAGKVISIPRPSDEA-EGSDVMPEQDDEVQELTTESEENVERHSEFSLSTPKSDDSKPREEVTSLGSASGSQDQDYRLLDYQKGEDDELLFLHKIKAIKETLQTSVRESIATVKIVLIPAGQEIIMPFRVDAPFRFLKEHFAHLLHIPHYVLQITHEGIIVGNNESLIQYGIKPQEIVQVEVFSTLPDQYPVRRIEGLSEG--SQIITVTIQTSIDRYEEVAVEIIKSDFHKPFLGGFRHKITGLEYHNAGTQTVPRKIPEK-DNLFCRDTQTVFQKKK-LQQTTNTTSTQMTKIGVYVSNMTDKLLKPGNYFSAAEYHARRLHAVIVIQTSYRRWHAKRYVESLRKQKKLRLEWEEEQELLKIQEKEEWIRMDYYRRHNPKTTEDFELLYNALELWRQEEVEQICHYSSEAERKAALCELLEKETQMIASIGRHRSAARMERQDAAIQAFLDKCSAPNVWRRGDGKTIEMDTQFTIRARELQSIYKCILLKDLSQDERLDILLTLKHTVKEHECKLTQEILELIDREVDLMMRGVKPHNLEGLRKRITTLFIHYIKTPLFNPEVAKYLKVPQDPLKFYDTIYFCHSCQNYLPSVEFSVSPTSHRVYRCRHCINLENETQRRESFLKYKCLLQRLYYSEADYGDNSQIAFLMQLQDIKYLTENIWASQSALSAWDDLNDLVMVRWDKHVEWSPWNCILLTKDESTAHLRLPSIEKGYGHHFVHKIKHKHILAKNYFSQIPTLASLILNDDEVEDIRSKHSTKSPPKIIITRRIQPH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IJP6-1", "uniprot_id": "A0A0R4IJP6_DANRE", "id": "A0A0R4IJP6-1", "name": "", "aln": "MS--------EKECETVNLEEQKMSSEAIQIETEEADEDQDVEHTQEISVDVITNPDTLLLEENS----AEPTSEDQRQQDDINKQGSE------------------------NKIISSND-----VGNSTATVKILLMPERHMITVAFTIGLTILDLKKHFSFEMRVPYDIIQITLDEKNVNDDQTLMDIGVQPHGMIQFEMSSLDPENYPMRPVKPQQEYNMPDVITVRVQTEADTYQDVVVEIERATQGKAFLGGYRHKLTNAEYHHAAIQTVPKKRPDRGIEMFSRDTQTVKPSKNQAQQCSRNAATQMRKIGCFVSNMEDKLISPGTYITAEEYHSKRLRAVITLQSYVRRWLAKCFTDSLRQAKEQRLAWLENEKRRKKEEKEKQIRDEYQRRMNPETKGDFDLLYNALKKWRIEEEEHINVTLSGAERKAALCALLEQETQFISSIERHRMAAATRNQEKAIKAFLNKCAEPKKWRAFDGKVTEMDTQFTIKAKELRDLYSSITQAHFTKDERLDVLLTLKHTVKEHKCKLAQEIVDLADREMDLLMRGMKKSNLEGLRKRISTLFLQYIKTPEFNPQVSRHLRVPRDPADLKKNIYLCRGCNEYQSSTNFSLKTNESAVGICRRCMELDNEARRREDFSLYKNILRCLRDTEAESSPGAKVTYLLQDQDLRYLVDFLWGAQSALSGWKDLHDLQFVRWEKHLDWSPWNCILLTKDEAAAHIKLENIEKAYDLVVIRNVKQKHTLARKYFSQIPAMAECLHG-AEIQPAALSNLLVSKPITEATK-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :. ::. :: . :* ::*. : .* :: :: :: :*.:* : .::.: ::: . . .** : :: * :* ****::*:* : * :.* :. : **.**:. : :*: ::** . : ::::*:: *::*: ::*.*: * *: **:* :. : .::*** :** * *::* *** :: *.****:***:*. ***:*. ****:: *:: .:*.****** .*: ** :..::*** :** :**** ***:.**.*::* ***::**:***.:*: *:* ** :.:.**: *. ** * ::: * .***: *: :* ** **:*. **::*****: ** ** :* : ******** ***:***:*:** *** * .*: **:***:**: *: ** :**. ********:*:**:.:*..* .:::*****:***********:***:***::* ***:**:***:* *********:***::***** ***:*:::*:**:** .: ..**:*:.*: * .*.:**:.... : **.*::*:**:::**.* ** :*: * :**: .:::::*:* **::**.: :*.:**.**. .:* ** :***:* ::*************::**::* .**:.* .::::*:** **::****:*.:*. : . *:: . : * :: ", "identical_positions": 311, "similar_positions": 255, "identity": "39.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110421-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48740-1", "uniprot_id": "MASP1_HUMAN", "id": "P48740-1", "name": "Mannan-binding lectin serine protease 1", "aln": "MRWL-----LLYYALCFSLSKASAHTVELNNMFGQIQSPGYPDSYPSDSEVTWNITVPDGFRIKLYFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGSFMSITFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSDNLFTQRTGVITSPDFPNPYPKSSECLYTIELEEGFMVNLQFEDIFDIEDHPEVPCPYDYIKIKVGPKVLGPFCGEKAPEPISTQSHSVLILFHSDNSGENRGWRLSYRAAGNECPELQPPVHGKIEPSQAKYFFKDQVLVSCDTGYKVLKDNVEMDTFQIECLKDGTWSNKIPTCKIVDCRAPGELEHGLITFSTRNNLTTYKSEIKYSCQEPYYKMLNNNTGIYTCSAQGVWMNKVLGRSLPTCLPVCGLPKFSR-------------------------KLMARIFNGRPAQKGTTPWIAMLSHLNG------QPFCGGSLLGSSWIVTAAHCLHQSLDPEDPTLRDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNTFENDVALVELLESPVLNAFVMPICLP-----EGPQQEGAMVIVSGWGKQFLQR-------------FPETLMEIEIPIVDHSTCQKAYAP--LKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWG--DDCGKKDRYGVYSYIHHNKDWIQRVTGVRN-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P98064-1", "uniprot_id": "MASP1_MOUSE", "id": "P98064-1", "name": "Mannan-binding lectin serine protease 1", "aln": "MRFLSFWRLLLYHALCLALPEVSAHTVELNEMFGQIQSPGYPDSYPSDSEVTWNITVPEGFRIKLYFMHFNLESSYLCEYDYVKVETEDQVLATFCGRETTDTEQTPGQEVVLSPGTFMSVTFRSDFSNEERFTGFDAHYMAVDVDECKEREDEELSCDHYCHNYIGGYYCSCRFGYILHTDNRTCRVECSGNLFTQRTGTITSPDYPNPYPKSSECSYTIDLEEGFMVSLQFEDIFDIEDHPEVPCPYDYIKIKAGSKVWGPFCGEKSPEPISTQTHSVQILFRSDNSGENRGWRLSYRAAGNECPKLQPPVYGKIEPSQAVYSFKDQVLVSCDTGYKVLKDNEVMDTFQIECLKDGAWSNKIPTCKIVDCGAPAGLKHGLVTFSTRNNLTTYKSEIRYSCQQPYYKMLHNTTGVYTCSAHGTWTNEVLKRSLPTCLPVCGVPKFSR-------------------------KQISRIFNGRPAQKGTMPWIAMLSHLNG------QPFCGGSLLGSNWVLTAAHCLHQSLDPEEPTLHSSYLLSPSDFKIIMGKHWRRRSDEDEQHLHVKRTTLHPLYNPSTFENDLGLVELSESPRLNDFVMPVCLP-----EQPSTEGTMVIVSGWGKQFLQR-------------FPENLMEIEIPIVNSDTCQEAYTP--LKKKVTKDMICAGEKEGGKDACAGDSGGPMVTKDAERDQWYLVGVVSWG--EDCGKKDRYGVYSYIYPNKDWIQRITGVRN-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58H9N0-1", "uniprot_id": "A0AC58H9N0_DANRE", "id": "A0AC58H9N0-1", "name": "", "aln": "MELT-----RVFVILAQCVWPLWTQVIPLSDMYGTIKSPNFPEPYPKETDLQWNITVPDGYQIRLYFMHFDIEPSYLCEYDYLKVYSDIEELAVFCGREKTDTERVPASDIILSPGNVLSVAFRSDFSNEERYFGFEAHFSAIDVDECRDRNDEDLVCDHFCHNYIGGFYCSCRFGFLLHSDNRTCKVECNKNVYTERSGEITSADFPKAYPKSSECKYSIELEEGFQVSLEFDDTFDIEDHPEVSCPYDFIKIQAGEKEFGPFCGEKSPGKIQTGSNIVNILFHSDNSGENLGWKLTYTSTGPECSPPTPLLNGQLEPLQPIYIFRDHITLTCDPGYLLRQGDEEFEHYQIECLRDGKWSSGVPLCKKVDCGPVDELLA-EVVFVNSDNSTVFGSQIQYSCRD---SAVNN---TYTCNQSGIWLSDD-GMPLPSCLPGVIEGNLSRPAGPESPTPLASTPLACGEQSQPFPAHQKRIVGGRPASPGLFPWQVLLSVEDVYRVPVVRWFGSGALLSPLWIVTAAHVLRS--HRLDLSVVP---VDPEHIQVHLG-LTDVRQKHLATNRSVEKIILHPQFDPQNYNNDIALVKLNQEVALSALVRPVCLPRPGLDSQVLTPNTLGIVAGWGINAANASASSSGLTSDSSSVSELLQYVKLPVVSQDECEASYASRSVNYNITGNMFCAGFYEGGQDTCLGDSGGAFVTQDGRSGRWVAHGLVSWGGPEECGSQRVYGVYTRVANYLQWLHTHMDAERWWVHGAD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. :: *. .: ::.: *.:*:* *:**.:*:.**.:::: ******:*::*:******::*.********:** :: : **.*****.****:.*..:::****..:*::**********: **:**: *:*****::*:**:* ***:*******:*******::**:*****:***. *::*:*:* ***.*:*:.******* *:*:***** *.*:*:* *********.****:***:.* * *******:* *.* :: * ***:******* **:*:* ::* **. * : *::** *. * *:*:: ::**.** : :.: :: :*****:** **. :* ** *** . * :.* . :* *.: *:*:***:: . ::* ***. * * .. .**:*** ::** **..****. * ** .:** : : * .*:**.. *::**** *:. . : :: :.*..::: :* *... : *:: *** ::*..::**:.**:* :. *. :* *:*** . .:: **:*** : : ..* * :::*:*. . *: :*:. :: ::* :*:*** ***:*:* *****.:** : . .:* * **** ::**.: ****: : :*:: .... ", "identical_positions": 307, "similar_positions": 224, "identity": "40.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110421-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88387-1", "uniprot_id": "FGD4_RAT", "id": "O88387-1", "name": "FYVE, RhoGEF and PH domain-containing protein 4", "aln": "---MEESNPAPTSCASKGKH----SKVSDLISHFEGGSV-----LSSYTDVQKDSTMNLNIPQTPRQHGLTSTTPQKLPSHKSPQKQEKDSDQNQGQHGCLANGVAAAQSQMECE-TEKEAALSPETDTQTAAASPDAHVLNGVRNETTTDSASSVTNSHDENACDSSCRTQGTDLGLPSKEGEPVIEAELQERENGLSTEGLNPLDQHHEVKETNEQKLHKIATELLLTERAYVSRLNLLDQVFYCKLLEEANRGSFPAEMVNKIFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAVELVKNMTERVPQFKSVTEEIQKQKICGSLTLQHHMLEPIQRIPRYEMLLKDYLKKLSPDAPDWNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKLAARNTSAQERYLFLFNNMLLYCVPRFSLVGSKFTVRTRVGIDGMKIVETHNEEYPHTFQVSGKERTLELQASSEQDKEEWIKALQESIDAFHQRHETFRNAIAKENDIPLEVSTAELGKRAPRWIRDNEVTMCMKCKESFNALTRRRHHCRACGHVVCWKCSDYKAQLEYDGGRLNKVCKDCYQIMSGFAESEE---KKRRGILEIESAEVSGNSEVCSFLQYMEKSKPWQKIWCVIPKQDPLVLYMYGAPQDVRAQATIPLLGYIVDDMPKSADLPHS-FKLTQSKSVHSFAADSEELKQKWLKIILLAVTGETPDGPSEHLDTLDNLPGPKEKSEC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZT5-1", "uniprot_id": "FGD4_MOUSE", "id": "Q91ZT5-1", "name": "FYVE, RhoGEF and PH domain-containing protein 4", "aln": "---MEESNPAPTSCTSKGKH----SKVSDLISHFEGGSV-----LSSYIDLQKDSTMNLNIPQTLGQPGLTSSPPRKFLPQHSPQKQENDPDQTQGQHGCLANGVVAAQNQMECE-DEKETTLSPEMAIQTAAASPDTHVLNGERNETITDSASSIANSHDENASDSSCRTPGTDLGLPSKEGEPGMDAELQERENGVNTMGLDTLDQHHEVKETNEQKLHKIATELLLTERAYVSRLDLLDQVFYCKLLEEANRGSFPAEMVNKIFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAVELVKTMTERVPQFKSVTEEIQKQKICGSLTLQHHMLEPIQRIPRYEMLLKDYLKKLSPDSPDWNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKLAARNTSAQERYLFLFNNMLLYCVPRFSLVGSKFTVRTRVGIDGMKIVETHNEEYPHTFQISGKERTLELQASSEQDKEEWIKALQESIDAFHQRHETFRNAIAKENDIPLEVSTAELGKRAPRWIRDNEVTMCMKCKESFNALTRRRHHCRACGHVVCWKCSDYKAQLEYDGGRLNKVCKDCYQIISGFTDSEE---KKRRGILEIESAEVSGNSEVCSFLQYMEKSKPWQKIWCVIPKQDPLVLYMYGAPQDVRAQATIPLLGYVVDDMPKSADLPHS-FKLTQSKSVHSFAADNEELKQKWLKIILLAVTGETPDGPSEHLATLNNLPGPKKKSEC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96M96-1", "uniprot_id": "FGD4_HUMAN", "id": "Q96M96-1", "name": "FYVE, RhoGEF and PH domain-containing protein 4", "aln": "---MEEIKPASASCVSKEKP----SKVSDLISRFEGGSS-----LSNYSDLKKESAVNLNAPRTPGRHGLTTTPQQKLLSQHLPQRQGNDTDKTQGAQTCVANGVMAAQNQMECE-EEKAATLSSDTSIQASEPLLDTHIVNGERDETATAPASPTTDSCDGNASDSSYRTPGIGPVLPLEERGAETETKVQERENGESPLELEQLDQHHEMKETNEQKLHKIANELLLTERAYVNRLDLLDQVFYCKLLEEANRGSFPAEMVNKIFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAMELVKNMTERIPQFKSVVEEIQKQKICGSLTLQHHMLEPVQRIPRYEMLLKDYLRKLPPDSLDWNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKLAARNTSAQERYLFLFNNMLLYCVPKFSLVGSKFTVRTRVGIDGMKIVETQNEEYPHTFQVSGKERTLELQASSAQDKEEWIKALQETIDAFHQRHETFRNAIAKDNDIHSEVSTAELGKRAPRWIRDNEVTMCMKCKEPFNALTRRRHHCRACGYVVCWKCSDYKAQLEYDGGKLSKVCKDCYQIISGFTDSEE---KKRKGILEIESAEVSGNSVVCSFLQYMEKSKPWQKAWCVIPKQDPLVLYMYGAPQDVRAQATIPLLGYVVDEMPRSADLPHS-FKLTQSKSVHSFAADSEELKQKWLKVILLAVTGETPGGPNEHPATLDDHPEPKKKSEC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58J936-1", "uniprot_id": "A0AC58J936_DANRE", "id": "A0AC58J936-1", "name": "", "aln": "MSAVSRSKNVKHKSIDAEKKGNVLNSCSDLKHHVHWQKTRFRRAVGGRTSAGSQGSAGAQVEDSASSFLKDASSVLRKSAVYSVSAMPPPAVLPKPKFQCPPK--ISAANVIDGEQTDNDKTRERTTSDQSASSECAASSFSASDQSSGWDVWSGWWSEEVRGQQEESGRGNGASVEKEEEQSRWKQDGLNEDMENDEDKPSVE--NDEDQQEQVNKLKLFKISSELLQTERAYVSRLHLLDQVFCVRLTEEALKGSFPVDVVKGIFSNVGSIYTFHSQFLLPDLETRMSQWDSKPRVGDVLAQLAPFLRMYAEYVKNFDSAMELLKLWMERSTQFSAIIQDIQSQEVCGSLTLQHHMLEPVQRVPRYEMLLKDYLKKLPEDDEDRSQAQKSLNIISMAATHSNMAIRKMENLKKLMEIYEMLGGEEDIVNPSNELIKEGQILKLAARNTSSMERYLFLFNNMLLYCVPKFSLVGQRFTVRTRVRVEGMKVLETSNEDYPHTFQVSGKERTLELQASSQQDKEDWIKAFQETIEIFQQKNETFKSACKEATD---EVSKEELGKRAPRWIRDNEVTMCMKCKEPFNALTRRRHHCRACGYVVCYKCSDHKASLRYDSNKLNKVCKDCYHILTGRADAEEPVCGKKKGILEIEAAQVSGNSFLCGFLQYSDRTKPSQRVWCVIPQHDALVLYLYGAPQDVKALCTIPLLGYQVEDVQRSVDHPPTGFRLCQSKYIHCFTAETEEVKLRWLKVIRKAVIGEMPECQTPVDGDLVNGCHEGATDGT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. : . .. . * .. *** :.. . :.. . .:.: . : : ::. : . . . : * .: :* . :: * :: : . *:: . : ... :.: * .. . :.* * * . :: : :: **. . :: ::..: ::.*: **.**:.*** ******.**.****** :* *** :****.::*: ****:.** :***:****:**.**.:*::.**:**:* :*****:**.****.**.*:**:* ** .**.:: ::**.*::*************:**:***********:**. * * .:*:***:*** **:*** ***********:******* **************************: ****************:*****.:******* ::***::** **:******:************* ****:****:**:*: *:*::***:.* : .* ***. ***********************.***************:***:****:**.*.**..:*.*******:*::* :::** *::******:*:***** :*.**** :::** *: *****::*.****:*******:* .******* *::: :*.* * : *:* *** :*.*:*:.**:* :***:* ** ** * . * : .. ", "identical_positions": 386, "similar_positions": 200, "identity": "49.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110427-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3UP38-2", "uniprot_id": "EFC4B_MOUSE", "id": "Q3UP38-2", "name": "EF-hand calcium-binding domain-containing protein 4B", "aln": "MATPSGREDSSSQ----TPGHGKQGSGACVEQLDHPEKLEVEMPD--QSAMWKKAQEFFQTCDSEGKGFIARTDMQRLHQELPLSLEELEDVFDALDADGNGFLTPEEFTTGFSHFFFSQNIQGEEEAD--QQVAQLQEEKVYQSRGEEDVGDMDHDEEAQFQMLMDRLGAQKVLEDESDVRQLWLQLRKDEPHLLSNFEDLLTTIFAQLQEAHEQKNELECALRKKIAAYDEEIQHLYEEMEQQIKSEREQFLLKDTERFQARSRELEKKLSAKEQELERLNQKQRKLEGQCAALHNDKHETKAENSKLRLTNQELARELERTSHQLQEAQQQLESLQREACELQQEKEMEVYRVTESLQREKSGLLKQLDFLRERNKHLRDERDITFQKDKAAKANTAASKASRKQRSGSVIGKYVDGRGILRSQSEEEEDVFSAPRRRSSVGLSAYLQAEEDLGTGEPGSGVPRRQALRRIISIEEDPLPQLLEGGFEKPLSRCPEEEEVSD------------QGTERQSVAAPVLDLIPTSPRGQPVGKETLYKEERVPSTPDRLFKIVFVGDSAVGKTSFLRRLCEARFSPGMAATVGIDYRVKTVTVDNAQVALQLWDTAGQERYRCISQQFFRKADGVAVMYDLTAKQSFLSIRQWLSSVEEAVGDRIPVLLLGNKLDNEKEREVPRGLGEQLAKENNLIFYECSACSGHNAQESLLHLARLLKEQEDTVRNDTIQVG-PPAKKKSCCG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5ZRP8-1", "uniprot_id": "A0A8I5ZRP8_RAT", "id": "A0A8I5ZRP8-1", "name": "small monomeric GTPase", "aln": "MATPSGREDSSSQ----APCHGEQGSEACVEELDHPERLEAEVPD--QSVMWKKAQEFFQTCDSEGKGFIARTDLQRLHKELPLSLEELEDVFDALDADSNGFLTPEEFATGFSHFFFSQNSQREEDAG--QQVVQLQEEKVYQSRGEEDMGGVDQDEEAQFQMLMDRLGAQKILDDESDVRQLWLQLKKDEPHLLSNFEDLLTTIFTQLQEAHEQKNELECALRKKIAAYDEEIQHLYEEMEQQIKSEREQFLLKDTERFQARSRELEKKLSAKEQELERLNQKQRRLEGQCAALHNDKHETKAENSKLRLTNQELARELERTSQQLQEAQQQLESLQREACELQQEKEMEVYRVTESLQREKSGLLKQLDFLRERNKHLRDERDITFQKDKAARASTAASKANRKQRSGSVIGKYVDGRGILRSQSQEEEEVFGPLRRRSSVGLSAYLQAEEELGTGEPGTGVPRRQALRRIISIEEDPLPQLLEGGFEKPLNKCPEEEEPSD------------QGTEGQSVAAPVLDLIPSSPRGQPVGKETLYKEERVSSAPDRLFKIVFVGDSAVGKTSFLRRLCEARFSPGMAATVGIDYRVKTVTVDNAQVALQLWDTAGQERYRCISQQFFRKADGVVVMYDLTAKQSFLSIRQWLSSVEEAVGDRIPVLLLGNKLDNEKEREVPRGLGEQLAKENNLIFYECSACSGHNTKESLLHLARLLKEQEDTVRKDIIQVG-PPAKKKSCCG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BSW2-2", "uniprot_id": "EFC4B_HUMAN", "id": "Q9BSW2-2", "name": "EF-hand calcium-binding domain-containing protein 4B", "aln": "MAAPDGRVVSRPQRLGQGSGQGPKGSGACLHPLDSLEQKETQEQTSGQLVMLRKAQEFFQTCDAEGKGFIARKDMQRLHKELPLSLEELEDVFDALDADGNGYLTPQEFTTGFSHFFFSQNNPSQEDAG--EQVAQRHEEKVYLSRGDEDLGDMGEDEEAQFRMLMDRLGAQKVLEDESDVKQLWLQLKKEEPHLLSNFEDFLTRIISQLQEAHEEKNELECALKRKIAAYDEEIQHLYEEMEQQIKSEKEQFLLKDTERFQARSQELEQKLLCKEQELEQLTQKQKRLEGQCTALHHDKHETKAENTKLKLTNQELARELERTSWELQDAQQQLESLQQEACKLHQEKEMEVYRVTESLQREKAGLLKQLDFLRERNKHLRDERDICFQKNKAAKANTAASRASWKKRSGSVIGKYVDSRGILRSQSEEEEEVFGIPRR-SSLGLSGYPLTEEEPGTGEPGPGGPYPRPLRRIISVEEDPLPQLLDGGFEQPLSKCSEEEEVSD------------QGVQGQIPEAPPLKLTPTSPRGQPVGKEALCKEESSPSAPDRLFKIVFVGNSAVGKTSFLRRFCEDRFSPGMAATVGIDYRVKTLNVDNSQVALQLWDTAGQERYRCITQQFFRKADGVIVMYDLTDKQSFLSVRRWLSSVEEAVGDRVPVLLLGNKLDNEKEREVPRGLGEQLATENNLIFYECSAYSGHNTKESLLHLARFLKEQEDTVREDTIQVG-HPAKKKSCCG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RS74-1", "uniprot_id": "A0A8M1RS74_DANRE", "id": "A0A8M1RS74-1", "name": "", "aln": "MASFTSTCGSKVD----------RGSHHRGDSKGTPSESD-------CSAVIEKTREFFQICDVEGKGFITRRDMQRLNGELPLSADDLENVFDSLDADANGYLTFEEFSSGFSEFMFGPSVVPVDPHGGEELVSRKSPEMLYESQWEERLSRGEDDEEKHFCMLMENLGASNIFEDPEEVRSLWVQLRRDEPHLLSNFEEFLTRVTYQIKEANQEKKEMETALKRKSATHDDEIQRLYEEMEQQIKNEKDRILLEDSERFLTRSQDMEHQLLSKEKELEILSNKQKRLERQCRDLLSEQRETSVENVKLKRYNEDLSRELDHTSQELSLAQEQLMLLQEQSSRLHEEREMEIYRVTESLQRERTSLLKQLDLLREMNKHLRDEKDISYQK-----PKTSAMKISWTQRSGSIAMKHAERKQSFK--SDEDEDVLPNSKRKNLIGINGHSMDLEDIVDG----RHPSKNQLRRIISIEEDPLPQLLQQGYQAQLREWSEDEELEETIDLQMSNIYPTTSTPTSASPPPAVSHTPTSPRGQPVGKETVQSEEGASSGPDRLFKVVLVGNSSVGKTSLLRRFCDDCFHSGTCATVGIDYSVKTLSVDNSQIALQMWDTAGQERYRSITKQFFRKADGVVVVYDITNEQTFTAVRQWLASVQEGAGEDIPIMLLGNKTDLDSQRVIPLGLGEKLAKDFQLMFYECSAFSNHNVTDSMIHMARILKEQEDREKEKTVSLVDSPSKKKSCC-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: . * : :** . . .. : .: .*::**** ** ******:* *:***: ***** ::**:***:****.**:** :**::***.*:*. . : . : * : * :* *: :* :. .*** :* ***:.***.::::* .:*:.**:**:::*********::** : *::**:::*:*:* **::* *::*:***:**********.*::::**:*:*** :**:::*::* .**:*** *.:**::** ** * :::**..** **: *::*:***::** :*. **:** **.::..*::*:***:**********::.******:*** *******:** :** ..*:* : . .:****: *:.: : :: *:*:*:*: :* . :*:..: *: * * . ******:*********: *:: * . .*:** .: .. . .* :. *:**********:: .** .* ******:*:**:*:*****:***:*: * .* .******* ***:.***:*:***:**********.*::********* *:**:* :*:* ::*:**:**:*..*: :*::***** * :.:* :* ****:**.: :*:****** *.**. :*::*:**:****** ::. :.: *:****** ", "identical_positions": 347, "similar_positions": 222, "identity": "46.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110429-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P16070-1", "uniprot_id": "CD44_HUMAN", "id": "P16070-1", "name": "CD44 antigen", "aln": "-MDKFWWHAAWGLCLVPLSLAQIDLNITCRFAGVFHVEKNGRYSISRTEAADLCKAFNSTLPTMAQMEKALSIGFETCRYGFIEG--HVVIPRIHPNSICAANNTGVYILTSNTSQYDTYCFNASAPPEEDCTSVTDLPNAFDGPITITIVNRDGTRYVQKGEYRTNPEDIYPSNPTDDDVSSGSSSERSSTSGGYIFYTFSTVHPIPDEDSPWITDSTDRIPATTLMSTSATATETATKRQETWDWFSWLFLPSESKNHLHTTTQMAGTSSNTISAGWEPNEENEDERDRHLSFSGSGIDDDEDFISSTISTTPRAFDHTKQNQDWTQWNPSHSNPEVLLQTTTRMTDVDRNGTTAYEGNWNPEAHPPLIHHEHHEEEETPHSTSTIQATPSSTTEETATQKEQWFGNRWHEGYRQTPKEDSHSTTGTAAASAHTSHPMQGRTTPSPEDSSWTDFFNPISHPMGRGHQAGRRMDMDSSHSITLQPTANPNTGLVEDLDRTGPLSMTTQQSNSQSFSTSHEGLEEDKDHPTTSTLTSSNRNDVTGGRRDPNHSEGSTTLLEGYTSHYPHTKESRTFIPVTSAKTGSFGVTAVTVGDSNSNVNRSLSGDQDTFHPSGGSHTTHGSESDGHSHGSQEGGANTTSGPIRTPQIPEWLIILASLLALALILAVCIAVNSRRRCGQKKKLVINSGNGAVEDRKPSGLNGEASKSQEMVHLVNKESSETPDQFMTADETRNLQNVDMKIGV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F6T0-1", "uniprot_id": "E7F6T0_DANRE", "id": "E7F6T0-1", "name": "CD44 antigen", "aln": "MWTLLFVVFATGSPAVLQAAPVQGNSGRCSFAGVFHIEGISRYSLTFQKAGELCQSLGYRLATQEQVTEAYKKGLRTCRYGWIDGQNVTFLPHINGPNCDSSSAEITFHAKAGEFLSDVYCFDPSD-----------------------------------------------SSPNCDDVKSEDVMNGNAARD-------SSFYAKP----------------------------------------------------------------------------------------------HEDFITEFKTEG------------------------FLVDVEEILERVKR--ETSLLSDMKPSTVPSMKNIEGIKDP--------------------------------------------------------TSKPHIGKTP-----------------------------------SVLLFDTEGSGSGLVD----PEPSHFTTSPVTTETAKSNLIENVIEENEEMVVPVETSNVN------------------------------------PIQVKEPRRVNVFSTTESNAKEMVS------------------------DGSSS--------------------TWMIITAFCVFIGVIVCIFVAIGTRDKWYGPSKSADITTEKNNKDYSKTETLPLSEKEQEIVALMNVTNMKNGQTVDITAADEHEKEYLM----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * * * : . . . * ******:* .***:: :*.:**:::. *.* *: :* . *:.*****:*:* ..:*:*: . ::. .: .:. *.***:.* *.*. ***.* . : .:: . *:.:. * .****:. : .*::. : *.* *: .: :*.: *.: : * :: **:* *:*. *: * * ...:***: . * :**. .::: .:. :::. . .: :** * *: :. ..* :.* .:::. *. ** * *:** * : :.:*:.: :*:.:* : .* . : : :* . : :.*.**:* *:* . :. : . : .: :: * ", "identical_positions": 95, "similar_positions": 151, "identity": "12.75%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110510-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49745-1", "uniprot_id": "TPO_RAT", "id": "P49745-1", "name": "Thrombopoietin", "aln": "--------------MELTDLLLVAILLLTARLT--LSSPVPPACDPRLLNKLLRDSYLLHSRLSQCPDVNPLSIPVLLPAVDFSLGEWKTQTEQSKAQDILGAVSLLLEGVMAARGQLEPSCLSSLLGQLSGQVRLLLGALQGLLGTQLPPQGRTTAHKDPSALFLSLQQLLRGKVRFLLLVEGPALCVRRTLPTTAVPSRTSQLLTLNKFPNRTSGLLETNFSVVARTAGPGLLNRLQGFRAKIIPGQLNQTSGSLDQIPGYLNGTHEPVNGTHGLFAGTSLQTLEAPDVVPGAFNKGSLPLNLQSGLPPIPSLAADG-YTLFPPSPTFPTP-GSPPQLPPVS-----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P40226-1", "uniprot_id": "TPO_MOUSE", "id": "P40226-1", "name": "Thrombopoietin", "aln": "--------------MELTDLLLAAMLLAVARLT--LSSPVAPACDPRLLNKLLRDSHLLHSRLSQCPDVDPLSIPVLLPAVDFSLGEWKTQTEQSKAQDILGAVSLLLEGVMAARGQLEPSCLSSLLGQLSGQVRLLLGALQGLLGTQLPLQGRTTAHKDPNALFLSLQQLLRGKVRFLLLVEGPTLCVRRTLPTTAVPSSTSQLLTLNKFPNRTSGLLETNFSVTARTAGPGLLSRLQGFRVKITPGQLNQTSRSPVQISGYLNRTHGPVNGTHGLFAGTSLQTLEASDISPGAFNKGSLAFNLQGGLPPSPSLAPDG-HTPFPPSPALPTTHGSPPQLHPLFPDPSTTMPNSTAPHPVTMYPHPRNLSQET", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P40225-1", "uniprot_id": "TPO_HUMAN", "id": "P40225-1", "name": "Thrombopoietin", "aln": "--------------MELTELLLVVMLLLTARLT--LSSPAPPACDLRVLSKLLRDSHVLHSRLSQCPEVHPLPTPVLLPAVDFSLGEWKTQMEETKAQDILGAVTLLLEGVMAARGQLGPTCLSSLLGQLSGQVRLLLGALQSLLGTQLPPQGRTTAHKDPNAIFLSFQHLLRGKVRFLMLVGGSTLCVRRAPPTTAVPSRTSLVLTLNELPNRTSGLLETNFTASARTTGSGLLKWQQGFRAKI-PGLLNQTSRSLDQIPGYLNRIHELLNGTRGLFPGPSRRTLGAPDISSGTSDTGSLPPNLQPGYSPSPTHPPTGQYTLFPLPPTLPTP---VVQLHPLLPDPSAPTPTPTSPLLNTSYTHSQNLSQEG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z2C6-1", "uniprot_id": "A0A8M6Z2C6_DANRE", "id": "A0A8M6Z2C6-1", "name": "", "aln": "MESNVTGDFMLSLGMDLNRVLVVVFSMVVSELSHVHTRPIDFVCDSEAR-RVMNKVKDLQEEKVICSGVDALPSSIQLPCISIHKATWERKSVQERRAEILLSLGTLAQDVRSARTLSQPGCGLTLLKRLEHSINNYLYVVR-------------------------LLHVEQGEQ------EGPAVERCLGQPSKDLG------LVLKYFGLLLTGKLELLIAEMAKWC-----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*. :*:..: : .:.*: : * .** . :::.. *:.. *. *..*. .: **.:.: . *: : : : :** :: * :.* :** * * :** :*. .:. * .:: : :: :*: *.:: *:. : *.*: : :* ** :: *: ", "identical_positions": 35, "similar_positions": 71, "identity": "9.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110510-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6QLM7-1", "uniprot_id": "KIF5A_RAT", "id": "Q6QLM7-1", "name": "Kinesin heavy chain isoform 5A", "aln": "---MAETNNECSIKVLCRFRPLNQAEILRGDKFIPIFQG---DDSVIIGGKPYVFDRVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVTKTNLSVHEDKNRVPFVRGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENIETEQKLSGKLYLADLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEDSALAAEICEETPVNDNSSIVVRIAPEER--------------QKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSENDAAKEEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESEPQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISG-------AIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQTVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDAEEVKKALELQMENHREAHHRQLARLRDEINEKQKTIDELKDLDQKLQLELEKLQADYERLKNEENEKSAKLQELTFLYERHEQSKQDLKGLEETVA---------------------------RELQTLHNLRKLFVQDVTTRVKK-SAEMEPEDSGGIHSQKQKISFLENNLEQLTEVHKQLVRDNADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRIKEAVRYKSSGKRGHSAQIAKPVRPGHYPASSPTNPYGTRSPE-CISYTNNLFQNYQNLHLQAAPSSTSDVYFA----SNGATS-VAPLASYQKANTDNGNATDINDNRSDLPCGYEAEDPAKLFPLHQETAAS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P33175-1", "uniprot_id": "KIF5A_MOUSE", "id": "P33175-1", "name": "Kinesin heavy chain isoform 5A", "aln": "---MAETNNECSIKVLCRFRPLNQAEILRGDKFIPIFQG---DDSVIIGGKPYVFDRVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVTKTNLSVHEDKNRVPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENVETEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEDSALGAELCEETPVNDNSSIVVRIAPEER--------------QKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMRDLSEFSVIVGNGEIKLPVEISG-------AIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQTVELKKRHLEESYDSLSDELARLQAHETVHEVALKDKEPDTQDAEEVKKALELQMENHREAHHRQLARLRDEINEKQKTIDELKDLNQKLQLELEKLQADYERLKNEENEKSAKLQELTFLYERHEQSKQDLKGLEETVA---------------------------RELQTLHNLRKLFVQDVTTRVKK-SAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRIKEAVRYKSSGKRGHSAQIAKPVRPGHYPASSPTNPYGTRSPE-CISYTNNLFQNYQNLHLQAAPSSTSDMYFA----SSGATS-VAPLASYQKANMDNGNATDINDNRSDLPCGYEAEDQAKLFPLHQETAAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q12840-1", "uniprot_id": "KIF5A_HUMAN", "id": "Q12840-1", "name": "Kinesin heavy chain isoform 5A", "aln": "---MAETNNECSIKVLCRFRPLNQAEILRGDKFIPIFQG---DDSVVIGGKPYVFDRVFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVTKTNLSVHEDKNRVPFVKGCTERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEAELSRWRNGENVPETERLAGEEAALGAELCEETPVNDNSSIVVRIAPEER--------------QKYEEEIRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSENDAAKDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESELQRLQEVSGHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISG-------AIEEEFTVARLYISKIKSEVKSVVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALELQMESHREAHHRQLARLRDEINEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDLKGLEETVA---------------------------RELQTLHNLRKLFVQDVTTRVKK-SAEMEPEDSGGIHSQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRIKEAVRYKSSGKRGHSAQIAKPVRPGHYPASSPTNPYGTRSPE-CISYTNSLFQNYQNLYLQATPSSTSDMYFANSCTSSGATSSGGPLASYQKANMDNGNATDINDNRSDLPCGYEAEDQAKLFPLHQETAAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ATT8-1", "uniprot_id": "A0A8M3ATT8_DANRE", "id": "A0A8M3ATT8-1", "name": "", "aln": "---MADISAECNIRVLCRFRPLNQSEILRGDKFMPTFQG---DDTVIIAGRSYVFDKVFPTNCTQEQVYNTCAQQIVKDVLDGYNGTIFAYGQTSSGKTYTMEGKLHDANGRGIIPRIAEDIFNHIYTMDENLEFHIKVSYFEIYMDKIRDLLDVTKTNLSVHEDKNRVPYVKGCTERFVSSPEEVMDLIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQEHVETEQKLCGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTMFICCSPSAYNDAETKSTLMFGQRAKTIMNSASVNLELTAEQWKRKYEKEKEKNKDLKESMQRLEAELNHWRNGESVVLITPVS----PAECDVTEDTAVDNQSHGQTELIPEQHN-------------SRYEEEIQQLYRQLDDKDDEINLQCQLVEKLKEQMLDQEELLACARADLERVQCDVRRLQADSESSKLEVQEVLQALEELALSYDHKSLEAQDNSRHNRRLTEELAHTTSALLSLESDFSRLQEVNGQQRKRITEVLNTLVKDLNDFSFILGNGDLRLPSELSG-------VLEEEYAVVCVYMSKVKSELKTLVKRCRQLESLQTDCHRKMEETGRELSSCQLLISQHEAKIRSLTEYMQNMELKKRQLEENYDCLSEELAKLQNTESILDRPLDTDES---VNVKSHKAVDQKSEVQREPQHKQLGRLRDDINHKQKIIDELTDDNQRLDLQLEQLSVEFSVLKSREHEKSRQLEELRYLHERQEQTRQDMKGLEETVVSAYRKYDISNDNNNGVYDRPAHFSLKARELQTLHNLRKLFVQDLTARVKR-SSELDPDDSSGCSTQKQKISFLENNLDQLTKVHKQLVRDNADLRCELPKLEKRLRSTAERVRALEEALREAKEGAMKDRRRYQQEVERIKDVMRSRNPFRRPQAALIAKPIRPGHYPASLSANHMFLRSRDQPITFSNAMFNSSS--EKQKLTSSKTESSLTSRTLSEHERQTHETTNCTQKLHITNGNSSDVNDN-SECRSSTITDEPQQKHHQEQPVAS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P17210-1", "uniprot_id": "KINH_DROME", "id": "P17210-1", "name": "Kinesin heavy chain", "aln": "MSAEREIPAEDSIKVVCRFRPLNDSEEKAGSKFVVKFPNNVEENCISIAGKVYLFDKVFKPNASQEKVYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGVIGDSVKQGIIPRIVNDIFNHIYAMEVNLEFHIKVSYYEIYMDKIRDLLDVSKVNLSVHEDKNRVPYVKGATERFVSSPEDVFEVIEEGKSNRHIAVTNMNEHSSRSHSVFLINVKQENLENQKKLSGKLYLVDLAGSEKVSKTGAEGTVLDEAKNINKSLSALGNVISALADGNKTHIPYRDSKLTRILQESLGGNARTTIVICCSPASFNESETKSTLDFGRRAKTVKNVVCVNEELTAEEWKRRYEKEKEKNARLKGKVEKLEIELARWRAGETVKAEEQINMEDLMEASTPNLEVEAAQTAAAEAALAAQRTALANMSASVAVNEQARLATECERLYQQLDDKDEEINQQSQYAEQLKEQVMEQEELIANARREYETLQSEMARIQQENESAKEEVKEVLQALEELAVNYDQKSQEIDNKNKDIDALNEELQQKQSVFNAASTELQQLKDMSSHQKKRITEMLTNLLRDLGEVGQAIAPGESSIDLKMSALAGTDASKVEEDFTMARLFISKMKTEAKNIAQRCSNMETQQADSNKKISEYEKDLGEYRLLISQHEARMKSLQESMREAENKKRTLEEQIDSLREECAKLKAAEHVSAVNAEEKQR----AEELRSMFDSQMDELREAHTRQVSELRDEIAAKQHEMDEMKDVHQKLLLAHQQMTADYEKVRQEDAEKSSELQNIILTNERREQARKDLKGLEDTVA---------------------------KELQTLHNLRKLFVQDLQQRIRKNVVNEESEEDGGSLAQKQKISFLENNLDQLTKVHKQLVRDNADLRCELPKLEKRLRCTMERVKALETALKEAKEGAMRDRKRYQYEVDRIKEAVRQKHLGRRGPQAQIAKPIRSGQGAIAIRG---------------------------------------------GGAVGGPSPLAQVNPVNS-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .*:*:*******::* *.**: * . :: : *.*: *:**:** .* :**:**: .* .**.*** *****************:**** : *. ******..*******:*: **********:***:*********:*.************:*:*.*********:::::*:***:***:**************:****:***::*.::**.*****.***************:***********************:*.*:::******:*****:*****.***:.*****:::*::****** **:****: * ..** *****:**::*******. * .: :** ** :** **.* : . :. . : : . : .:. : * .:**:******:*** *.* *:**:*:::****:. :* : * :* :: ::* :.:::* **:**********:.**:** * :::.:. * :** :. :.: : .:: .:*:::..:*:***:*:*. *::**.:.. :. *: : ::*. :**::::. :::**:*:* *.:.:** ::*. *.:.::*:. ::*.. :********:::** * *: * *** ***. *.* :* *:*: * : . .: : :. .: : : **.: :*:..***:* **: :**:.* .*:* * ::: .::. ::..: *** :*::: **:**:::*:****:**. :***************: *::: : :.::..* :************:***:************************.* ***:*** **:*******:*::*** **:***:.:* : :* * ****:*.*: . : . : : ", "identical_positions": 472, "similar_positions": 286, "identity": "43.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110511-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LUU3-1", "uniprot_id": "A0ABK0LUU3_RAT", "id": "A0ABK0LUU3-1", "name": "Sushi domain-containing protein 4", "aln": "MYHGMNPSNGDGFLEQQLQQQQPQSPQRLLAVILWFQLALCFGPAQLTGGFDDLNVCADPGVPENGFRTPSGGVFFESSVARFHCQDGFKLKGSSKRLCVKRLNGTLGWIPSDKPLCIQEDCRIPRIEDAEIHNKTYRHGDKLIINCHEGFKIRYPDLYNMVSLCRDDGTWDNLPICQGCLRPLASSNGYVNISEFQTSFPVGTVIAYRCFPGFKLEGSEYLECLHNLIWSSSPPRCLALEAQVCPLPPMVSHGDFICHPRPCERYNHGTVVEFYCDPGYSLTSDYKYITCQYGEWFPSYQVYCIKSEQTWPSTHETLLTTWKIVAFTATSVLLVLLLVILARMFQTKFKAHFPPRGPPRSSSSDPDFVVVDGVPVMLPTYDEAVNGSSSALGPGYLASVGQGCPLPVDDQSPPAYPG-SGDTDTGP---GESETCDSTSGSSEMLQSLYSPPMCQGGSRPAPDTPDTISSTAGEVASTSPGIDIADEIPLMEEDP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BH32-1", "uniprot_id": "SUSD4_MOUSE", "id": "Q8BH32-1", "name": "Sushi domain-containing protein 4", "aln": "MYHGMNPSNGDGFLEQQLQQQQPQSPQRLLAVILWFQLALCFGPAQLTGGFDDLNVCADPGVPENGFRTPSGGVFFESSVTRFHCQDGFRLKGSTKRLCMKHFNGTLGWVPSDKPVCIQEDCRIPQIEDAEIRNKTYRHGEKLVIDCHEGFKIRYPDLYNLVSLCRDDGTWDNLPICQGCLRPLASSNGYVNISEFQTSFPVGTVIAYRCFPGFKLEGSENLECLHNLIWSSSPPRCLALE--VCPLPPMVSHGDFICHPRPCERYNHGTVVEFYCDPGYSLTSDYKYITCQYGEWFPSYQVYCIKSEQTWPSTHETLLTTWKIVAFTATSVLLVLLLVILARMFQTKFKAHFPPRGPPRSSSSDPDFVVVDGVPVMLPTYDEAVNGSSSALGPGYPASVGQGCPLPVDDQSPPAYPG-SGDTDTGP---GESETCDSTSGSSEMLQSLYSPPMCQGGSRPAPDTPDTISSTAGEVASTSPGIDIADEIPLMEEDP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VX71-1", "uniprot_id": "SUSD4_HUMAN", "id": "Q5VX71-1", "name": "Sushi domain-containing protein 4", "aln": "MYHGMNPSNGDGFLEQQQQQQQPQSPQRLLAVILWFQLALCFGPAQLTGGFDDLQVCADPGIPENGFRTPSGGVFFEGSVARFHCQDGFKLKGATKRLCLKHFNGTLGWIPSDNSICVQEDCRIPQIEDAEIHNKTYRHGEKLIITCHEGFKIRYPDLHNMVSLCRDDGTWNNLPICQGCLRPLASSNGYVNISELQTSFPVGTVISYRCFPGFKLDGSAYLECLQNLIWSSSPPRCLALE--VCPLPPMVSHGDFVCHPRPCERYNHGTVVEFYCDPGYSLTSDYKYITCQYGEWFPSYQVYCIKSEQTWPSTHETLLTTWKIVAFTATSVLLVLLLVILARMFQTKFKAHFPPRGPPRSSSSDPDFVVVDGVPVMLPSYDEAVSGGLSALGPGYMASVGQGCPLPVDDQSPPAYPG-SGDTDTGP---GESETCDSVSGSSELLQSLYSPPRCQESTHPASDNPDIIASTAEEVASTSPGIDIADEIPLMEEDP---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FEC4-1", "uniprot_id": "SUSD4_DANRE", "id": "E7FEC4-1", "name": "Sushi domain-containing protein 4", "aln": "MFHHADKGG------KKSAFGHPVCGQIILSIILLRPPLLVTAFPVNT---VEEQICKDPGFPEHGIRTPSIGKFFENSVARFSCADGFSLKGPAKIICTRFYNGSLGWKPSLKPVCLSEDCLPPFIEDADVTNRTYRPGDSLIISCHEGFQIRYPDTETMESVCQADGTWDNQPTCQGCLRPLIPPHSYMNISETKFSVPVGTVVHYQCFPGYKLEGPELLECMYNLIWSDTPPRCLDVE--ACSLPPMIEHGDYTCHPHPCDRYIHGTVVEYYCYPGYSLANDYKYITCQYGQWFPQMQLYCVKDETTWPGFQDSLLTTWKVVACTATSVLLALLLVITAKMFHYKCKSQQSPSDEP-DESRDPNILVVDGVAVPLPSYEEAISGNYCQP-PNDLPPDGLESAQHSEEQNPPSYPGHTGSQNSVPLDTGDVENCDSLSDTSECLQGLQ-PSSSHPGGLNMSEKTNAITS-MEETASTSPSIDIADEIPLVEDGEEDC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* : .. :: :* . * :*::** * . . * : ::* ***.**:*:**** * ***.**:** * *** ***.:* :* : **:*** ** :.:*:.*** * ****:: *:*** *:.*:* *****:***** .: *:*: ****:* * ******** ..:.*:**** : *.*****: *:****:**:*. ***: *****.:***** :* .*.****:.***: ***:**:** ******:** *****:.**********:***. *:**:*.* ***. :::******:** *******.***** *:**: * *:: .* . * ..* **:::*****.* **:*:**:.*. . *. .. * .. ::*.**:*** :*. :: * *: *.*** *.:** **.* *. .: . .:..: *:* *.*****.*********:*:. ", "identical_positions": 250, "similar_positions": 131, "identity": "50.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110512-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TPQ3-1", "uniprot_id": "SHPRH_MOUSE", "id": "Q7TPQ3-1", "name": "E3 ubiquitin-protein ligase SHPRH", "aln": "MSSRRKRAPPMKVDEERQQQLHWNMHEDLRSEPLTMTVG-EQACSDAD-SSSDCIIIDEGPPESALHRDKKRRSETVSVLEATEEE------TRLSVTLNVTVSPYRVDNSWKAFLGDFALQLLPKESLVEHFSERTFTLSPSESSSQFLIYVHSECKNVEKQENVLEGSAGVCSKGIRVESSFSSDMLQDLAWLQKRRGIKLYQRPDGTHTIKVGIYILEAGLTRLDFMSDAGSRMKKFNQLMKRVMEKLHNFIIPDVLEEEEEGSESEPEGQDIDELYHFVKQTHQQETRSVQVDVQHPALIPVLRPYQREAVNWMLQQEQFRSAPPADNSLHFLWREIVTPDGLKLYYNPYTGCIIRDFPHAGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPTHCPREKVKNREIQDTEYEPKEKVHCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIFRYDVQRNRGLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYK-EDVFDKTKKQAVGSPRKIEKELRKSVNKDADSEYLPSNTSDDDE-PYYYYCKAGKSRSKL-KKPALLTKKGKGQ-SVHLDSQGDAPAAGVCASTDVHVSENTCVSEDKQTQEAKDCAESPNPAAEELAQSNTSSPCETSDYRFECICGEFDQIGHKPRVQCLKCHLWQHAKCVNYEEKNLKVKPFYCPHCLVAMEPVSTRATLIISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKHGFLQPHFLAEQDIVIITYDVLRSELNYVNIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSGINRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWIRLLYHPYCKKNPQHLYSFIAKIMWRSAKKDVIDQIQIPPQTEEMHWLHFSPVERHFYHRQHEVCCQDAIVKLRKISDWALKLSSLDRRTVSSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAHRQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLGAKHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALQPVQQSIRELQRKIHSNSPWWLNVIHRAMEFSVDEELVQRVRNEISSNYKQQTDKLSMSEKFRDCRGLQFLLTTQMEELHKFQKLVREAVKKLEKPPSREVIESATVCHLRPARLPLNCCVFCKADELFTEYESKLFFNTVKGQTAIFEEMIEDEEGLVDDRVPTTTRGLWAVSETERSMKAILSFARSHRFDVEYVDEGSVSMDLFEAWKKEYKLLHEYWMTLRNRVSAVDELAMATERLRVRHPKEPKPNPPVHHIIEPHEVEQNRIKLVNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGINPEPCPICARQLGKQWAVLTCGHCFCNECTSIIIEQYSVGSHRSSIKCAICRQTTSHKEVSYVFTSEKANQEDDIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFTQISRIKTFQENLSAFKYDPHINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATIEERMQAMLKTAERSHTSSSGKHSEASVLTVAGLADLFTKENEELE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q149N8-1", "uniprot_id": "SHPRH_HUMAN", "id": "Q149N8-1", "name": "E3 ubiquitin-protein ligase SHPRH", "aln": "MSSRRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKEEVAHRDKKRCSKVVSFSKPIEKEETVGIFSPLSVKLNIVISPYHFDNSWKAFLGELTLQLLPAQSLIENFSERSITLMSSESSNQFLIYVHSKGEDVEKQK---KEPMSICDKGILVESSFSGEMLEDLGWLQKKRRIKLYQKPEGNHIIKVGIYLLEAGLAKLDFLSDANSRMKKFNQLMKKVMEKLHNSIIPDVLEEDEDDPESEPEGQDIDELYHFVKQTHQQETQSIQVDVQHPALIPVLRPYQREAVNWMLQQECFRSSPATESALHFLWREIVTSEGLKLYYNPYTGCIIREYPNSGPQLLGGILADEMGLGKTVEVLALILTHTRQDVKQDALTLPEGKVVNYFIPSHYFGGKLKKTEIQNIEFEPKEKVQCPPTRVMILTAVKEMNGKKGVSILSIYKYVSSIYRYDVQRNRSLLKRMLKCLIFEGLVKQIKGHGFSGTFTLGKNYKEEDICDKTKKQAVGSPRKIQKETRKSGNKDTDSEYLPSDTSDDDDDPYYYYYKSRRNRSKLRKKLVPSTKKGKSQPFINPDSQGHCPATSDSGITDVAMSKSTCISEFNQEHETEDCAESLNHADSDVPPSNTMSPFNTSDYRFECICGELDQIDRKPRVQCLKCHLWQHAKCVNYDEKNLKIKPFYCPHCLVAMEPVSTRATLIISPSSICHQWVDEINRHVRSSSLRVLVYQGVKKDGFLQPHFLAEQDIVIITYDVLRSELNYVDIPHSNSEDGRRLRNQKRYMAIPSPLVAVEWWRICLDEAQMVECPTVKAAEMAQRLSGINRWCISGTPVQRGLEDLFGLVVFLGIEPYCVKHWWVRLLYRPYCKKNPQHLYSFIAKILWRSAKKDVIDQIQIPPQTEEIHWLHFSPVERHFYHRQHEVCCQDVVVKLRKISDWALKLSSLDRRTVTSILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLTSLQKKCGTECEEAHRQLVCALNGLAGIHIIKGEYALAAELYREVLRSSEEHKGKLKTDSLQRLHATHNLMELLIARHPGIPPTLRDGRLEEEAKQLREHYMSKCNTEVAEAQQALYPVQQTIHELQRKIHSNSPWWLNVIHRAIEFTIDEELVQRVRNEITSNYKQQTGKLSMSEKFRDCRGLQFLLTTQMEELNKCQKLVREAVKNLEGPPSRNVIESATVCHLRPARLPLNCCVFCKADELFTEYESKLFSNTVKGQTAIFEEMIEDEEGLVDDRAPTTTRGLWAISETERSMKAILSFAKSHRFDVEFVDEGSTSMDLFEAWKKEYKLLHEYWMALRNRVSAVDELAMATERLRVRDPREPKPNPPVLHIIEPHEVEQNRIKLLNDKAVATSQLQKKLGQLLYLTNLEKSQDKTSGGVNPEPCPICARQLGKQWAVLTCGHCFCNECISIIIEQYSVGSHRSSIKCAICRQTTSHKEISYVFTSEKANQEEDIPVKGSHSTKVEAVVRTLMKIQLRDPGAKALVFSTWQDVLDIISKALTDNNMEFAQISRVKTFQENLSAFKRDPQINILLLPLHTGSNGLTIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTIVHRFLIKATIEERMQAMLKTAERSHTNSSAKHSEASVLTVADLADLFTKETEELE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WD98-1", "uniprot_id": "X1WD98_DANRE", "id": "X1WD98-1", "name": "", "aln": "MSSRRKRAPPVRVDEDAKRRLDWNMHEDRKNE--GACEDILESVPAPSDSCLPVPVLEQGFISSAGTEEEPSEERPSCSTQDSPPD---------TIELNVMP-ISVLDQGWNALIGEFNLHPK----IPIEVADGSFCLQQTGDTLSMTLNTLEMEDGRGRSD-------PLCS--VPVACSLGGLLLEDLDWLQKRKVIKLCHASGG-VPVKLKVFLIESGLGRPEFLSEGNGRIKKASQLLQKLMELFYDFIIPEVMENEEEACDTDLERQNVEELYDHVRHLHQTEAAEQSFHVQHPALIPILRPYQSQAVNWMLRREKYKSSSSPEQRLHFLWREMVTICGKKLFYNPYTGCLIREFPLAGVDWPGGILADEMGLGKTVEVLALILCNTRQNLEHGVLTLPVGRSVNYFVPPPP----LERQRIIKHEPRPKEKIIYPAVREMLLTAIKEMKVGKGASINAIFAYLRTMYKYDTLKNRNHIKKILTKLISENIVEQIKGRGLAGSFKLGKNYKEKKKKPVTARTKSADQPAPRRTSRRVSAPDKDSSLTSYTTTASDS----------ASEDSMNPPLLTEELKSDPDSLLDPENPLQKKPVDITDDKEIPDKPQLQITEDVHIESNKPDLMQTSKPEVETPTRASVVPFNTPDYRFECICGELGLVDYKPRVQCLNCLLWQHAECVNYKEENLETTPFYCPHCLVAMTPVSTGATLIISPSSICHQWVDEINRHIHTSSLRVLVYQGVKRHGFIQPHILAEQDVVITTYDVLRTELNYVDIPHSNSKDGRRFRNQKRYMAIPSPLVAVEWWRVCLDEAQMVECTTAKAAEMALRLTSVNRWCVSGTPVQRGLEDLYGLVLFLGVDPYWVKYWWDQLLYRPYRHGNTAPLYNVIGQLLWRSAKKDVIDQIQIPPQTEEIHWLNFSPVERHFYHRQHEVCSQDALVKLRKISDWSLKLGSLDRRTVTTILYPLLRLRQACCHPQAVRGEFLPLQKSTMTMEELLKSLQKKCRVECEEAHRQLVCALNGLAGIHIIRSEFVDAAEMYREVLRSSEEHKARLKTDSLQRLHATHNLMELLSANHPGIPPTLRDDSLKEEAEQLKQHYMAKVNSEVSEAHQNLQPVLQHIKEQRRKVNLRSPWWLDVIQQAMQYSMDDDLVSRIQNELTCSYKQQANKLSMADKFRDARGLQFLLSTQMDDLMKSQKTVQDAVKKLEGPPSQQVIEEATLCHLRPVRLPLNNCVFCKADELFTDYESKLFSHTVKGQTAIFEEMIEDEEGLVDDRLPTTSRGLWAASETERALKAILSFAKVRRLESGLIEEGNSFMELFESWKKEYKLLHEYWMSLRDHVSAIDELGMATERLRVRLPDEPKPK--VLHIIEPHEVEQNRIKLLNDRAVAKSQLQKKLGQFLYLTNLEKSQDKSTGGLNPEPCPICARPLGQEWAVLTCGHCFCNECIAIIVEQYSIGNRRRAIKCAICRQTTSHAEISYVFTTQNNHQGQDIPVKGSHSTKVEAVVRVLKKVQMTDPGAKSLVFSTWQGVLDIIAKALFDNNMEFAQINGIHKFQENLSAFKYEEKINILLLPLHTGSNGLNIIEATHVLLVEPILNPAHELQAIGRVHRIGQTKPTFVHRFLIKSTIEERMQAMLKTAEKSHSSTSMKHSEASVFTVADLADLFTEDSETLE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**********::***: :::*.****** :.* . :. . .. *. ::.:. ... .:: .. . : : :: **: .*:.*:*::*:: *: : ..:: :: * : .: .: : . . .. :.. :*. : * .*:.. :*:** ****:: *** : . * :*: ::::*:** : :*:*:...*:** .**::::** ::: ***:*:*::*: ::: * *:::***..*:: ** *: . ...********:***** :******::* ::*:...:. *******:** * **:*******:**::* :* : ********************* :***::::..**** *: ****:*. ::. .* . * .****: *..* *:***:***: **.** :*: *: ::::**. :**. :*::*. ** *.:*:****:*::*:*.****** :. * : .. .: *: * **. . *: .*. ....: *.. : :. :. . ... .:: . . ::* : .. : . . . : . : * :*.**********:. :. *******:* *****:****.*:**: .*********** **** *********************:::************:.**:***:*****:** ******:*****:******:****:********************:**********.*.****** **:.:****:************:***:***::** **:** :***:** : *. **..*.:::********************:***:****************.**.:*********:***.*******::************************************.****** .**********************:.*:. ***:************.:******************* *.**********. *:***:**::***:* *:**:**:* * ** * *:* :**:: .*****:**::*:::::*::**.*::**::..****:.****::****.*******:***::* * ** *::***:** ***::***.**:*****.***** ***********:****** :*********************** ***:***** *****::*******: :*:: ::**. *:***:*************:**::***:***.********* * ****: * ***************:**:***.*********:************::**:********** **::************** :**:****:*.:* :************ *:*****::: :* :*****************.* *:*: *****:*******.*****:*** ******:**. ::.********* : :***************.***********************************:*******:**************:**:.:* *******:***.******::.* **", "identical_positions": 999, "similar_positions": 408, "identity": "59.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110517-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14980-1", "uniprot_id": "NUMA1_HUMAN", "id": "Q14980-1", "name": "Nuclear mitotic apparatus protein 1", "aln": "MTLHATRGAALLSWVNSLHVADPVEAVLQLQDCSIFIKIIDRIHGTEEGQQILKQPVSERLDFVCSFLQKNRKHPSSPECLVSAQKVLEGSELELAKMTMLLLYHSTMSSKSPRDWEQFEYKIQAELAVILKFVLDHEDGLNLNEDLENFLQKAPVPSTCSSTFPEELSPPSHQAKREIRFLELQK--VASSSSGNNFLSGSPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRIDRLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELT-------------TLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQLATAAEER--EASLRERDAALKQLEALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKES----LKVTKGSLEEEKRRAADALEEQQRCISELKAETRSLVE-----------------QHKRERKELEEERAGRKGLEARLQQLGEAHQAETEVLRRELAEAMAAQHTAESECEQLVKEVA-AWRERYEDSQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVA-----------------GIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGR-------------------QFCSTQAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERG----------------------------------------------RAQADLALEKAARAELEMRLQNALNEQ---RVEFATLQEALAHALTEKEGKDQELAKLRGLEAAQIKELEELRQTVKQLKEQLAKKEKEH---------ASGSGAQSEAAGRTEPTGPKLEALRAEVSKLEQQCQKQQEQADSLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALAS----------AQRELAAFRTKVQDHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETASNSARAAERS----SALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAELLRAQRELG-ELIPLRQKVAEQERTAQQ----------------------------------------------------LRAEKASYAEQLSMLKKAHGLLAEENRGLGERAN-LGRQFLEVELDQAR---------------EKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVKVLEER----QRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQ--------------QQKLKAVQAQGGESQQE--------------------------------------------------AQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQELQEQLRSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSRE----PQAKPQLDLSIDSLDLSCEEGTPLSITSKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPIPARS-----------QAPLESSLDSLGDVFLDSGRKTRS--ARRRTTQIINITMTKKLDVE-EPDSANSSFYSTRSAP-ASQASLRATSSTQSLARLGSPDYGNSALLSLPGYRPTTRSSARRSQAGVSSGAPPGRNSFYMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPSLS-LGTITDEEMKTGDPQETLRRASMQPIQIAEGTG------------------------------------------ITTRQQRKRVS------------LEPHQGPGTPESKKATSCFPRPMTPRDRHEGRKQSTTEAQKKAAPASTKQADRRQSMAFSILNTPKKLG--NSLLRR------GASKKALSKASPNTRSGTRRSPRIATTTASAATAAAIGATPRAKGKAKH--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9Q7G0-1", "uniprot_id": "NUMA1_MOUSE", "id": "E9Q7G0-1", "name": "Nuclear mitotic apparatus protein 1", "aln": "MTLHATRAATLLSWVNSLHVADPVETVLQLQDCSIFIKIINTIHDTKEGQQILQQPLPERLDFVCSFLQKNRKHPSSTQCLVSVQKVIEGSEMELAKMIMLFLYQSTMSSRNLRDWEQFEYGVQAELAVILKFMLDHEESLNLTEDLESFLEK--VPYTHASTLSEELSPPSHQTKRKIRFLEIQR--IASSSSENNFLSGSPSSPMGDILQTPQFQMRRLKKQLADERSNRDDLELELSESLKLLTEKDAQIAMMQQRIDHLALLNEKQAASSQEPSELEELRGKNESLTVRLHETLKQCQNLKTEKSQMDRKISQLSEENGDLSFKVREFANHLQQLQGAFNDLIEEHSKASQEWAEKQARLENELSTALQDKKCLEEKNEILQGKLSQLEDQATRLQESPAPEKGEVLGDALQLDTLKQEAAKLATDNTQLQTRVETLECERGKQEAQLLAERSRFEDEKQQLASLIADLQSSVSNLSQAKEELEQASQAQGAQLTAQLTSMT-----------------GLNATLQQRDQELASLKEQAKKEQAQMLQTMQEQEQAAQGLRQQVEQLSSSLKLKEQQLEEAAKEQEATRQDHAQQLAIVAEAR--EASLRERDTARQQLETVEKEKDAKLESLQQQLQAANDARDNAQTSVTQAQQEKAELSQKIGELHACIEASHQEQRQVQARVTELEAQLKAEQQKTTEREKVVQEKAQLQEQLRALEES----LKITKGSLEEEKRRAADALKEQQCRATEMEAESRSLME-----------------QREREQKELEQEKAGRKGLEARIQQLEEAHQAETEALRHELAEATASQHRAESECERLIREVE-SRQKRFEARQQEEARYGAMFQEQLMALKGE--KTGQEVQEE----------------------AVEIHSEGQPGQQQSQLAQLHASLAKAIQQVQEKEVRAQKLVDDLSALQEKMAATNKEVACLKTLVLKAGEQQETASLELLKEPPRAANRASDQLGEQQGR-------------------PFSSTHAAVKAMEREAEQMGGELERLRAALIKSQGQQQEERGQQEREVARLTQERG----------------------------------------------QAQADLAQEKAAKAELEMRLQNTLNEQ---RVEFAALQEALAHALTEKEGTDQELAKLRGQEAAQRTELKELQQTLEQLKIQLVKKEKEHPAGGASGEDASGPGTQSETAGKTDAPGPELQALRAEISKLEQQCQQQQQQVEGLTHSLKSERACRAEQDKALETLQGQLEEKARELGHNQAASAS----------AQRELQALRAKAQDHSKAEEEWKAQVARGQQEAERKSSLISSLEEEVSILNRQVLEKEGESKELKRLVVAESEKSQKLEERLRLLQVETASNSARAAERS----SALREEVQSLREEVEKQRVVSENSRQELASQAERAEELGQELKAWQEKFFQKEQALSALQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRFREELEQSKQAAGGLQAELMRAQRELG-ELGSLRQKIVEQERAAQQ----------------------------------------------------LRAEKASYAEQLSMLKKAHGLLAEENRGLGERAN-LGRQFLEVELDQAR---------------EKYVQELAAVRTDAETHLAEMRQEAQSTSRELEVMTAKYEGAKVKVLEER----QRFQEERQKLTA--------------QVEELSKKLTEHDQASKVQ--------------QQKLKAFQAQRGESQQE--------------------------------------------------VQRLQTQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQKLQEQLQDLEELQKENKELRSEAERLGRELQQAGLKTKEAEQTCRHLTAQVRSLEAQVAHADQQLRDLGKFQVATDALKSRE----PQVKPQLDLSIDSLDLSLEEGTPCSVASKLPRTQPDGTSVPGEPASPISQRLPPKVESLESLYFTPTPARG-----------QAPLETSLDSLGDAFPDSGRKTRS--ARRRTTQIINITMTKKLELE-EPDSANSSFYSTQSAP-ASQANLRATSSTQSLARLGSPDDGNSALLSLPGYRPTTRSSARRSQARMSSGAPQGRNSFYMGTCQDEPEQLDDWNRIAELQQRNRVCPPHLKTCYPLESRPTLS-LATITDEEMKTGDPRETLRRASMQPAQIAEGVG------------------------------------------ITTRQQRKRVS------------SETHQGPGTPESKKATSCFPRPMTPRDRHEGRKQSSTADTQKKAAPVLKQADRRQSMAFSILNTPKKLG--NSLLRR------GASKKTPAKVSPNPRSGTRRSPRIATTTTGTATVATT---PRAKGKVKH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IH76-1", "uniprot_id": "A0A0R4IH76_DANRE", "id": "A0A0R4IH76-1", "name": "", "aln": "MKFNKNKAGPLLTWMNSVFPENQIWEFGHMRDGFRLLEICFKLKGREDVEAYKTLSLYNKLEIIFNDLHDD-FHLTDRQRFLILGKISEGLDLELQLAKVALLLCYCSFKKTNP--VALNSRTESDITFMFRFVRDDASGLCLDEGLDQFLDQDSVMNLANSSSGSSCSSPFYIDEESPMFGRFQRPPRVQFQELCTVASSSDSSPMQDLMSTPHFQLKKLRKELAHEGDVRDELEKELADHISIISEKEGLISQLQHRVER--MLREQGELEKDHKAALLELQEKNESLLHRVHEVLKQCQDLKTDNSQKEKKIDELTEENGTLSAQLRNVFSQLARAEQEVAKLTVVHESAQTEWKNRKELLEKELNEAVTHKECLSEQVLILQGKISVLEDELKKAQ---SQERGEVLGPIMEWEKLKQELADLTLQLAQLQESISHLEKKKAEVEALLAEERCSFEKETARLQLVVFDLEKSINSIRLERETLQEALKTQKEMLSAQISALERDVSRLQQVEVQLTAEIKISADLRQQREELEGKVASLDRMVHSLHAEIQGLEVERASQQDAINSLISDLQIARATVQEYEKKLEEHQKVVAENNSLKNEACTMQQELNNHLKAIGDLQAEVNELRFEKTEEENKVSEALVKIESLQTEILHLCEKISLKDEEIRNLTKEYESVDNELKLVKEQNVEINAMIKSNRKEHEETVEKLQQELHCAASAASEKQEQMLVLSAEVTSLKEQICRYSENEAQKQQELSILEAQHNVLKENLTSLQNQLAEATTSASQKESEFILLQQELSHQETLREQTQELEKIKREELEGIVSELQAKIIEVSSIASEREACVSSLQYEMKDQLSKAKQCEADLRNEMKEKVGNLQELLDAANHGIAEKEHHLESLNQSLKQMELLYCQKEEEIIASQQAKQQLENNIAEQKQQLDEIQQNREILRNERDHLSTRVSSLQEEIHRSQQDFSDLQTDHNVLKEKLVNLQDQVEQAMITASQKESELLLLQQELSHQETLREKALELEAIKREEFEKKVKELQDRILEVSTLASQREAQVISLENEMRDQQLSANQSKDNLCREWQEKLGILKGELDVVSRDAADKDHQLESLDQKLKEMEMVVLQKEKDVMETHQAKEDLEKRIAELEECKQKLEIMRNERDHLSTEVASLKEEIHSYQDTQMQKQQTISVLEVENNALKENMAALEKQLAEEITTASQKNSELQN-KLHQQESLHEKAQELEIGRHEEFERRVRELQAKVQEVSTLASEKEAVAYSLQEELTGHLKAKVSEDDLRRVLEEKVETLQREIETASCDATSKDGLLQTLDQKLRQMEMLCQQKEDAVFEIQNSKEDLQKEMNELVSKNQELEGCLQHLEMVKKEKDLLSNEVTSLKEQINDQSLRAKQSEADLCIVFEEKIETLQGQLESSSCDVSDKEKHLQTLHQKVSQMDLLCQQKENAVLEMQNAKEDLQKKIDELVSEKQQLEGCLQNLEMVKSERDLLSTEVTSLKDQLNDQDLKAKQSEDDLRKVLEEKIKNLQGQLETASRDVSEKDQLLQTLDQKVTQMDQLCKQKEKYALDLLQVKENLEKRIGEITVEKQQLEGCQQNLETVSKDKDNLLNELTFLKVEIQSYQEKEVQMKHELSVLENEHNILQENLDTLQKQVVELTASASQKESELQNEVCKQEKLQEKAQKLEKDAGDLQAKILEISTLASEREAQISSLKDEINSQHLKAKQSEDDLLRVFEEKIENLQGQLEIARLDVSDKDQLLQTLNQKLKQMEELCKQKETCVLEMHQTKEDLEKKTVELQADKSQQNQQNLEMLRQEKDHLKSLNQTIRRECEASRKIRAELELNVEEQTASILALKKASQQWEEQNQELLEQLKAKTEAVEHYKAQVEKAMNHYNGKKQLLLEAQELNKTLEQSLEVSK---REAKALETELTLARMELNQANDKEKSLAAKVKTLEAQVDFADRQLREKRRIADDGEDLRQKENLYFRVPEKQQDTSADSLEFELNDSLNTTCRSAVPGE--SSTPLVRSSERLAAKRRALGAESLETLYFTPMGKQGYKRKVDHNDGFERKLESSITSIGDLVVDSAKKLTASARRRRTTQVINITLAKKAQGSSESEESFSSLHSARSHPNLAVHQSRPISIDFSEDGPATTLSKADTLQNLPGYRRSTVHSVG---------PPRATSTFCIGAENEPEHAADDWMRIAELQSRNKACLPHLKSSYPLESRPSLGPSFTVTDEDLRLGDPSETIRRASMMPGQILESLNSRRFSLAPETSSSQAPARSHPQRATMLPCQIQSSTAAHRASQLTKTSSRSHTSENKRSPLAPKRPASQLQGPDTPEAKKLASCFPRPMTPKGRFGNSQNR----------PPVSPAERRQSVMFTVVNTPKNSARGDSRLQRGLNKLRNSTRKSPAVASRALRSAVSGKSPLDVTLRKSPRNKSPKTSNAKKIKLRIKV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.:: .:...**:*:**:. : : . :::* :::* ::. :: : .: ::*::: . *:.: * :. : :: *: ** ::** : :* .:. :: :::::.:::*: *. ..* * *.*:.**:: * *: .. *.* : :.. * .:*: .. .. .. *.* :*** *::.**:**:::*:*:**.* . **:** **:: .:::**:. *: :*:*::: :*.*: . . * **: ***** *:**.*****:***::** ::**.:*:**** ** ::*:. .:* : : . .* *..* ** ::: **:**. *: .*:**.*: *****:* **:. .: * . *:***** :: :.**** * *: : :*** :. ** ::.: ** * ** **.*. :* :: **:.*:..: :* *::* ::: *:**:::: :.* ::*: :** . . .. .: :* * . :. ::.* *.*: . ::* :: * :: *:: : * : .*.:: * :*:: :* : ::::. * :. **.: : .: : ..:: :* *: :* : .: : .*:: ::::::: * . *:: : . : ::. *. **:*: * :: ::* : ::*: . * * *:: * *::* : :: *. : *:* : :: * * : ** ** * : .: :.: . :* ** ::*:: *: : : : * *: : :.::*: : .* . *: : . . ::* :*:***:: :.::.: *:* *: . . :: : *.:: .: * ** * .. :: *.. :..: * :* :. :** . .*.: ::.* **: :*: ** . * * : :*: **: .*.*:*:* : : .:* :: *. : * :: *.: : : :*:.* : :*. *: : .:. *:*::.::. ..::: . .* ..* .. .:...*. ..*: ::* :*: .. :* *:: : : :* :: * :: : :* *.. :.. :.:.::::: ..* ..**. : :* :::: * * :: *. .. * * * .:.:*:*:::..: : .:: .: : . : *:* :::. .: * * .*. *:: ::. : * :*: . *. :: : : :*. *: **:. : * * * . * .* **:.: :: .:* *:.* ** *: :*: .:* :*:. * *. : * :*.:*: . :: :: .*:* * :::: *: *.. ::. :. : :. ::*. :.. : *:*: ::* . :: *.:** : :: .* : ::* .**: .:.:*: *: : * :** **. * :*.**** *:*** .**:.*** : ** : **: : .* **: * ** * :: ::*::. : *:*:*::***** .**:***: :: : *:.:* : * * * ***::. ::. : * :* ..*.: .. ::* . .****:***** :. : **:*: *:** . **.:* : ******:****::** : . *.:.: **::*::* * : . *. * * .:. .:* .***** :* *. .* . .:* :*: :: . *** ******.**:.* ****:.*******:*. *:***::: *** **:***** * ** *. . :*. ..*.:.* . ***.***:** :*********:.*. . :: . . *:****: *:::****: . :* *:* .:::*: : .* **.. .. : .* :. : * * : ", "identical_positions": 518, "similar_positions": 778, "identity": "20.86%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110518-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIK1-1", "uniprot_id": "CDHR5_RAT", "id": "Q9JIK1-1", "name": "Cadherin-related family member 5", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGAPALLWPPLLLPLLTVLFGHLPGTLAQAQVCSANQT--------VFTMNENTTVSGPLADIFVPEDQYVTLGQLSTPNAFKVEGNKLFLIVTPDYE---ENSLLEAVLECKR--GDTLVTQFRVFVAVLDINDNAPEFPFTIKEYNVSEDTRVNTIVIPETELKATDA-DKDDILVYTLQEVTPNASKFFSLVGIN--SPALKLDQTLDYYK---SPNMTFRLLARDTREEN------------------------------------------------------------------------------------------------------------VIPSHTATATVVLNVLPADLRTPWFLPCS-------------------------------------------------------------------------FTDDYFCIQAQYHTVIPTGHKLPSPLILSPGPIYAVDGDQAINQPIVYSIMMGNTDD----------------------------TFIINKDDGNLTMAK-------------------SIPSPMTFTLVVRA----EQADMARYSVTQAVVEARDVTGNPLQ----------------------------FSQSLYFGTVVLGSEAGTAVKDKTFP--SEILRIQAQYLGFP-DLNSAVTYQVTNS-------------------SEFIMNKDILLTTVPMETERTIRIEVEANNTVTK------------------------------------------------------------------------------------------------------------------DIATTIVEIQVSEREPPST-----------------------ESPTPPEAGGTTGPSSNTTLETPSTSGTSQGPATTSSGGSAG-----------------------------------------------------------------------------------------------------------------PFPPAGTTLSPLTSAPTVPGGSPTLGISTSPQTATPGGDATQTPKPGTSQPMVPTPGASTSSQPATPSGSS-----------------------------------------------------------------------TQTPKPGTSQPMVPTPGASTSSQPATPSGSSTQTPRPGTSQPMVPTPGASTSSQP-----------------------------ATPSG-STQTPKPGTSQPTTT--GPISGVGELGDGQRFSTVDMAVLGGVLGALLLLALIFLIILIHKHYRHRFTCCSGKAKEP----QPSGYDNLTFLPDNKAKWSPTSNRKPEPGPEPVQPPLRPPSPMSS---SPTPPSSMPPSPQPKASGSPKTVQAGDSP----------------SAVRSILTKERRPEGEGGYKAVWFGKDIGAEADVVVLNEPTADVDSASASGSEGSDDDDDPDQKKSLRLGAVADNTYV-------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VHF2-1", "uniprot_id": "CDHR5_MOUSE", "id": "Q8VHF2-1", "name": "Cadherin-related family member 5", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGAPALLWPSLLLPWLTVLFGQPPGTLAQTQVCSVNQT--------IFRVEENTTVSEPLVNIFVPDGLHVTLGPLSTPYAFRIEGKDLFLNVTPDYE---ENSLLQADVECKR--GDAVVVRLEVFVAVLDINDNAPKFSFEIKTFNVSEDTKVNTTVIPETQLKATDA-DINDILVYTLQEVTPNASKFFSLEGVN--YPALKLDQTLDYFK---NQNMTFMLLARDTWEEN------------------------------------------------------------------------------------------------------------VEPSHTATATLVLNTLPADLRTPWFLPCS-------------------------------------------------------------------------FTDGYVCIHAQYSAVVPTGHKLPSPLIMSPGPIYAVDGDQAINQSIIYSIIAGNTDG----------------------------TFIINAHDGNLTMTK-------------------SIPSPMKFTLLIRA----DQEDMAQYSVTQAIVEARSVTGNPLQ----------------------------FSQSLYYGTVVLGSEAGTAVKDKTFP--SEILRIQAQYPGFP-DLNSAVTYRVTNS-------------------SEFMMNKDIMLTAVPMEEARTIRVEVEASNTVTK------------------------------------------------------------------------------------------------------------------DTATAVVEIQVSERE---------------------------RTPTPPEAGGTTGPSSNTTMEAPLTSGTSQRPATTSSGGSVG-----------------------------------------------------------------------------------------------------------------PFPPGGTTLRPPTPASSIPGGSPTLGTSTSPQTTTPGGDSAQTPKPGTSHPTAPTSRTSTSLMTTSSRSDS-----------------------------------------------------------------------TQTPKPGTSQPMVPIPGASTSSQPATPSGSSPQTPKPGTSQSTATGP---------------------------------------------------ISLPST-------GAGEQGDGQRFSTVDMAVLGGVLGALLLLALICLVILVHKHYRHRLACCSGKASEP----QPSGYDNLTFLPDHKAKWSPTPNRKPEPSPKLAQPPLRPPSPMSS---SPTPPSSTPPSPQPKASGSPKTVQAGDSP----------------SAVRSILTKERRPEGEGGYKAVWFGKDIGAEADVVVLNEPTADVDSASASGSEGSDDDD-PDQKKTLRFGVDADNTYI-------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBB8-1", "uniprot_id": "CDHR5_HUMAN", "id": "Q9HBB8-1", "name": "Cadherin-related family member 5", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSWALLWPPLLF---TGLLVRPPGTMAQAQYCSVNKD--------IFEVEENTNVTEPLVDIHVPEGQEVTLGALSTPFAFRIQGNQLFLNVTPDYE---EKSLLEAQLLCQS--GGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDR-DKDDILFYTLQEMTAGASDYFSLVSVN--RPALRLDRPLDFYE---RPNMTFWLLVRDTPGEN------------------------------------------------------------------------------------------------------------VEPSHTATATLVLNVVPADLRPPWFLPCT-------------------------------------------------------------------------FSDGYVCIQAQYHGAVPTGHILPSPLVLRPGPIYAEDGDRGINQPIIYSIFRGNVNG----------------------------TFIIHPDSGNLTVAR-------------------SVPSPMTFLLLVKG----QQADLARYSVTQVTVEAVAAAGSPPR----------------------------FPQRLYRGTVARGAGAGVVVKDAAAP--SQPLRIQAQDPEFS-DLNSAITYRITNH-------------------SHFRMEGEVVLTTTTLAQAGAFYAEVEAHNTVTS------------------------------------------------------------------------------------------------------------------GTATTVIEIQVSEQEPPST-----------------------DVPPSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTG-----------------------------------------------------------------------------------------------------------------PHPPSGTTLRPPT--SSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGT-----------------------------------------------------------------------AQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPPGMGTSTSHQP-----------------------------TTPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCCGKAPEP----QPQGFDNQAFLPDHKANWAPVPSPTHDPKP--------AEAPMPA---EPAPPGPASPGGAPEP---PAAARAGGSP----------------TAVRSILTKERRPEG--GYKAVWFGEDIGTEADVVVLNAPTLDVDGASDSGS--GDEGEGAGRGGGPYDAPGGDDSYI-------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q2D0-1", "uniprot_id": "A0A8M1Q2D0_DANRE", "id": "A0A8M1Q2D0-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKSQTLRLELTPTQRAAQSMLYVKKYQLVTRSHSPPWLFVCIRIWEMDMTFSHKTIIIIFGCLFASFLPKICSTDKICTIPSE--------PVTIKENNTADIVVVHINTTTKDVTLNLTENPGNAFQLRGSELIAKKGLDFETLLGHEELTVQVRCNK--TGYRSITLTVIVHVANINDNPPSFGQREYTLDINELTPVNTSIA----LFEATD-DDSEVLYYSLEPTVN---RYFRLKTMY--TPNILVNKVLDYDV---IQQVKLILYVQDTPLQSQ----------------------------------------------------------------------------------------------------------PGERSFTATTTITVNIKDIDNRPPWFQPCTK----------------------------------------------------------------------VTVGSAKICLSLGYRGRVNLTEKQDGALQLQPGPVYARDGDRSRNEEISYKIVRGNEDN----------------------------IFQIDENSGNISMLK-------------------PPDIAGPISLLVLAF---QLLNRDQFATTSVTIDVMKKSRNPPR----------------------------FEKERYEGYVYSNSGPENMVLRDKMS--NRPFRVRARDEDFASGINPDIKYEVQYS-------------------SYVNITTDGFILLKKAVRTDAFALQLRAVDVSTG------------------------------------------------------------------------------------------------------------------ESGTAALSVNV---------------------------------------------------------LPPVGIQSQDESYRAG-----------------------------------------------------------------------------------------------------------------DMALLGFVMAALLVLCLIVIGYLISRVKKGNSDAFKLSECLGPCLKFTQPPNRPRDSMQFTNDGFLNEGDT-----------------------------------------------------------------------GRSRSRRADLREQRLDAVQGARVRVIPRERQRHCSSCG---------------------------------------------------------------------------------------------------------FQVHANHSHYSPGLPVKEKPSKQR----VKSILAKERRKDDKKTVWFKESEDS---------------SDIEV---EIIPDTIG--------------LKPEDDE----------------DKVEGDFASNPPEDG---------GMVLGELTMLSIKDSRSRETDITDSKDGLNTDRRDQ-------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJB6-1", "uniprot_id": "CADN2_DROME", "id": "Q9VJB6-1", "name": "Putative neural-cadherin 2", "aln": "MVDPLKIFWVLTNSTYLVTKFVRIGIADKNDSPPYFDRFLYETEIDENADLQSTVLTVNAKDHNESTNIRYQITGGNIGNAFAVQNTTGVIYVASPLDYETRPRYELRLEATRNRKNNYTTVVINVRDVNDNPPVFDRQTYRTQITEEDDRNLPKRILQVTATDGDVDRPINIVYFLTGQGIDPDNPANSKFDINRTTGDIFVLKPLDRDQPNGRPQWRFTVFAQDEGGEGLVGYADIQVNLKDINDNAPQFPQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNAKLIYSIEKNVIEEETGAPIFEIEPETGLIKTAVCCLDRERTPDYSIQVVAMD--GGGLKGTGTASIRVKDLNDMPPQFTKDEWVTEVDETNGTYIPETPILTVTVQDE-DETNTFQYKVVPNSGFGADKFAMVRNGDGTGSLKIIQPLDYEDPLQSSGFRFRIQVNDKGDDGPGGSDKYHVAYSWVVVKLRDINDNVPKFDREHIEVSIYEDTKVGTILEQFKATDADQGGHSKVAYKIVRSTNRKRQFAISDRGAVSIQRPLDRETQDRHHIQILAIDDGSPARTATATLTVIVKDVNDNAPTFAQDYKPTLPENVSGKKILEVAAKDPDDRLRGNGGPFTFRLDPLASDEIKAGFKVEYDRRGDNENGVAIISSLRPFDREAQKSYAIPIEIKDNGAPAMTGTSTLTVTIGDVNDNKMQPGSKSVLVYNYQGQSQDTPIGRVYVNDPDDWDVPDKKYYWEVQEHQRFKLDTDTGILTMRAGTRRGRYQLRFKVYDREHGQEDIPANLSVTVRDITAEAVQQAGSMRLSHITDEDFVRTWNPVKNQVEPSKLERFRNKLAELLYTDRDNVDVFSVQLKEGSPYPLTDVHFAARSATQQPYFKAVRLNGVVQMHREEIEKDVGLNITMVNINECLHEGKGKCGSNSCTSKVELGKKPYTVSVNRTALVGVRLDISAQCVCRARNFTHQDHNCRTHLCYNGGRCVETRNGPKCVACPVGYNGPRCQQSTRSFRGNGWAWYPPLQLCQESHLSLEFITRVADGLILYNGPIVPPKPEETVISDFIALELEQGYPRLLIDFGSGTLELRVKTKKTLDDGVWHRLDIFWDTENVRMVVDFCRTALVSEMEDGTPPEFDDNACQARGQIPPFAESLNLNQPLQLGGLYRQHFDQTLYNWQYAFSSKGFDGCIRNVIHNSEHYDLAFPALARNSFPACPQTDEVCLKTEHTARCWEHGNCVASLVQAKCHCQPGWMGPGCNVPTIPTTFKAQSYVKFALSFEPDRFSTQLQLRFRTREQGGELFRVSDQHHREYAILELRRGHLQFRYNLNSMRNEEQLLTLTAIAVNDGQWHVIRISRYGSAALMELDGGESRRYNESFHFTGHQWLTIDKQEGVYAGGKAEYTGIKTFEVQSDFQRSCLDDIRLDGKHLPLPPAMNGTQWGQATMARNLERNCPSNRPCSNVICPDPFDCVDLWNEYECTCSEGRIMSSDTKGCVDRNECLDLPCLNGATCINLEPRLRYRCICPEGYWGENCELVQEGQRLKLSMGALGAIFVCLIIILILALIFVLYSRKRKTTKKKKRSGPEKDVRETVISYEDEGGGEDDMTAFDITPLQIPISAQGGPPDIAACKMPIIYPVMTLLPPGQELNVAYLMEERKQRIDKDNNAPPFDDLRNFTFEGSGSIAESLSSLASGTDDENQDFNYLQNWGPRFNALAAMYVHDKAKASSQLPSDGGGGSGDGPGPGASSSSPLGGGGTGGGSGIPGNVLAVVATGSGAGPGGGGGSSGLMPLPEVDKVVL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A0B4LHM7-1", "uniprot_id": "A0A0B4LHM7_DROME", "id": "A0A0B4LHM7-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRINHQWIYYAILSLCWFNKATLGAILDSRCYLEGGGSAESFLATEDLAVGSIIG---------KLRINGDANAETGDINLSLREKNAPVEIHPG------TKELALSVELDKEGVRGPSSIYVNVICIRRHSTDPSFVIPVNVRVTDVNDNAPQWIGTPYTLTLSEVTVPGTRILQGARAEDADQPGPFSTVEYQVLPGPYSEYVQFLNPLEG----TLVLKKALDYEQ---LQNFTVKLRAQDQ----------------------------------------------------------------------------------------------------------------GTPPRHSDTLLRVVITDADDQNPKFQRES-------------------------------------------------------------------------------------YSAEIPADGRPGELRMRPEPLKAVDQDEGICAPIQYTIVQSQDAK----------------------------YFRIHPHNGAISLLTPIG----------------YADVANGATLVVKAT---QIDNPDRYALTTVQLTRPGSHSDLST--------------------------LAFVQKRFVMRIREDTAVGNRILALPTN---------KPGKHLKYVIPDPVNSQFFSVG---------------------SLGELVLAKPLDYEKMTKHEFQVLATDGMTN--------------------------------------------------------------------------------------------------------------------STAELTLEVIDVN------------------------------------DWEPRFRETHYEFMVPKSSLQSRADSFEGVLIG-----------------------------------------------------------------------------------------------------------------KVEAADGDRNDKLELSLRGQHAGLFEIDSTGNIYMRPEQLQSLNESTVHLIAIATDTGVPPRSTSVPVSVTMEG--------------------------------------------------------------------LTLARSGWNSNMLGMFGMIMGLFLMIIVALSCYIVRSKKQGKSASSG----------------------------------------------------------------------------------------------LGLGRNRVHSQAHSSVSSANLVTHEK---LAGNGNGNGASVTSGGVSVLHMKHGGNITMANPMNNGLHHVASGASSSMALGSSAALLERERERERDRERQRESYAAT---------------VRIFLPGIVSRASANG------QLFEEDEIEHDSLQTENNNRKVAATGVASGGVTTISTTPANAGSNLLSATDAMGSSENNLTVYF------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . : * ::** .*.: :.* . . . . * : * : : : **: . . : ..* . : : : : : . * * . * : : . : . : *. . * :. . * ::: . : : : : . * : : : .. : :: * .: : :.* . . * . : . :.: : . . . . . :.. :. : : .. ", "identical_positions": 20, "similar_positions": 90, "identity": "1.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110518-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JIK1-1", "uniprot_id": "CDHR5_RAT", "id": "Q9JIK1-1", "name": "Cadherin-related family member 5", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGAPALLWPPLLLPLLTVLFGHLPGTLAQAQVCSANQTVFTMNE----------------NTTVSGPLADIFVPED---------------QYVTLGQLSTPNAFKVEGN-KLFLIVTPDYE---ENSLLEAVLECKRGDTLVTQFRVFVAVLDINDNAPEFPFTIKEYNVSEDTRVNTIVIPETELKATDADKDDILVYTLQEVTPNASKFFSLVGINS--PALKLDQTLDYYK---SPNMTFRLLARDTRE------------------------------------------------------------------------------------------------------------ENVIPSHTATATVVLNVLPADLRTPWFLPCS-----------------------------------------------FTDDYFCIQAQYHTVIPTGHKL--------------------------PSPLILSPGPIYAVDGDQAINQPIVYSIMMGNTDD----------------------------TFIINKDDGNLTMAK-------------------------------------SIPSPMTFTLVVRAEQADMARYSVTQAVVEARDVTG--------------NPLQFSQSLYFG--------TVVLGSEAGTAVKDKTFPSEILRIQAQYLGFP-DLNSAVT----------------------------YQVTNSSEFIMNKDILLTTVPMETER----------------------------------------------------------------------------------------------------------------------TIRIEVEANNTVTK-------------------DIATTIVEIQVSEREPPSTESPTPPEAGGTTGPSSNTTLETPSTSG----------------------------------------------------------------------------------TSQGPATTSSGGSAGPFP-------------------------------------------------------------------PAGTTLSPLTSAPTVPGGSPTLGISTSPQTATPGGDATQTPKPGTSQPMVPTPGASTSSQPATPSGSSTQTP--------------------KPGTSQPMVPTPGASTSSQPATPSGSSTQTPRPGTSQPMVPTPGASTSSQP-----------------------------ATPSG-STQTPKPGTSQPTTT--GPISGVGELGDGQRFSTVDMAVLGGVLGALLLLALIFLIILIHKHYRHRFTCCSGKAKE----------PQPSGYDNLTFLPDNKAKWSPTSNRKPEPGPEPVQPPLRPPSPMSSSPTPPSSMPPSPQPKASGSPKTVQA--------------GDSPSAVRSILTKERRPEGEGGYKAVWFG-----KDIGAEADVVVLNEPTADVDSASASGSEGSDDDDDPDQKKSLRLGAVADNTYV-------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VHF2-1", "uniprot_id": "CDHR5_MOUSE", "id": "Q8VHF2-1", "name": "Cadherin-related family member 5", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGAPALLWPSLLLPWLTVLFGQPPGTLAQTQVCSVNQTIFRVEE----------------NTTVSEPLVNIFVPDG---------------LHVTLGPLSTPYAFRIEGK-DLFLNVTPDYE---ENSLLQADVECKRGDAVVVRLEVFVAVLDINDNAPKFSFEIKTFNVSEDTKVNTTVIPETQLKATDADINDILVYTLQEVTPNASKFFSLEGVNY--PALKLDQTLDYFK---NQNMTFMLLARDTWE------------------------------------------------------------------------------------------------------------ENVEPSHTATATLVLNTLPADLRTPWFLPCS-----------------------------------------------FTDGYVCIHAQYSAVVPTGHKL--------------------------PSPLIMSPGPIYAVDGDQAINQSIIYSIIAGNTDG----------------------------TFIINAHDGNLTMTK-------------------------------------SIPSPMKFTLLIRADQEDMAQYSVTQAIVEARSVTG--------------NPLQFSQSLYYG--------TVVLGSEAGTAVKDKTFPSEILRIQAQYPGFP-DLNSAVT----------------------------YRVTNSSEFMMNKDIMLTAVPMEEAR----------------------------------------------------------------------------------------------------------------------TIRVEVEASNTVTK-------------------DTATAVVEIQVSERE----RTPTPPEAGGTTGPSSNTTMEAPLTSG----------------------------------------------------------------------------------TSQRPATTSSGGSVGPFP-------------------------------------------------------------------PGGTTLRPPTPASSIPGGSPTLGTSTSPQTTTPGGDSAQTPKPGTSHPTAPTSRTSTSLMTTSSRSDSTQTP--------------------KPGTSQPMVPIPGASTSSQPATPSGSSPQTPKPGTSQSTATGP---------------------------------------------------ISLPST-------GAGEQGDGQRFSTVDMAVLGGVLGALLLLALICLVILVHKHYRHRLACCSGKASE----------PQPSGYDNLTFLPDHKAKWSPTPNRKPEPSPKLAQPPLRPPSPMSSSPTPPSSTPPSPQPKASGSPKTVQA--------------GDSPSAVRSILTKERRPEGEGGYKAVWFG-----KDIGAEADVVVLNEPTADVDSASASGSEGSDDDD-PDQKKTLRFGVDADNTYI-------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBB8-1", "uniprot_id": "CDHR5_HUMAN", "id": "Q9HBB8-1", "name": "Cadherin-related family member 5", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGSWALLWPPLLF---TGLLVRPPGTMAQAQYCSVNKDIFEVEE----------------NTNVTEPLVDIHVPEG---------------QEVTLGALSTPFAFRIQGN-QLFLNVTPDYE---EKSLLEAQLLCQSGGTLVTQLRVFVSVLDVNDNAPEFPFKTKEIRVEEDTKVNSTVIPETQLQAEDRDKDDILFYTLQEMTAGASDYFSLVSVNR--PALRLDRPLDFYE---RPNMTFWLLVRDTPG------------------------------------------------------------------------------------------------------------ENVEPSHTATATLVLNVVPADLRPPWFLPCT-----------------------------------------------FSDGYVCIQAQYHGAVPTGHIL--------------------------PSPLVLRPGPIYAEDGDRGINQPIIYSIFRGNVNG----------------------------TFIIHPDSGNLTVAR-------------------------------------SVPSPMTFLLLVKGQQADLARYSVTQVTVEAVAAAG--------------SPPRFPQRLYRG--------TVARGAGAGVVVKDAAAPSQPLRIQAQDPEFS-DLNSAIT----------------------------YRITNHSHFRMEGEVVLTTTTLAQAG----------------------------------------------------------------------------------------------------------------------AFYAEVEAHNTVTS-------------------GTATTVIEIQVSEQEPPSTDVPPSPEAGGTTGPWTSTTSEVPRPPE----------------------------------------------------------------------------------PSQGPSTTSSGGGTGPHP-------------------------------------------------------------------PSGTTLRPPT--SSTPGGPPGAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTP--------------------EPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPMPPGMGTSTSHQP-----------------------------TTPGGGTAQTPEPGTSQPMPLSKSTPSSGGGPSEDKRFSVVDMAALGGVLGALLLLALLGLAVLVHKHYGPRLKCCCGKAPE----------PQPQGFDNQAFLPDHKANWAPVPSPTHDPKP--------AEAPMPAEPAPPGPASPGGAPEP---PAAARA--------------GGSPTAVRSILTKERRPEG--GYKAVWFG-----EDIGTEADVVVLNAPTLDVDGASDSGS--GDEGEGAGRGGGPYDAPGGDDSYI-------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YYJ8-1", "uniprot_id": "A0A8M6YYJ8_DANRE", "id": "A0A8M6YYJ8-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDLRPKGAAVFIFLLVIFTFSKCS---EAQDLCSVPLPFIFIKE----------------NNTIDALVTTINAAEG---------------VTAVITGQNPPDLFDINDEYQLIAKTVMDYEKFDKDNPYLVNIECTKPGSTSTSLLLRIVLEDINDNPPSFKESWYSLEVKELTKVDTSVG---LITATDPDESDRLYYRLESPEG----EFDVETSFN--PNILVKKLLDYDK---VKQVTMTLYAQDTQIG-----------------------------------------------------------------------------------------------------------SSAEVSHTATATVVVNIIDIDNRPPWFQPCTE--------------------------------------------YIFETSTVCINSGYNGVVTLKEQE--------------------------TDPLKLMPGPVYGIDGDAGIKELIGYTFMGGNEDG----------------------------IFNINTDTGNITMLK-------------------------------------PVDVVGPFVLTVMAFQKLNPDQFATTTVILKVALTASE------------FPPKFTKESYEG--------FISEDAGVDSLVLEGKTSNRALRVQATDEDFSNGYNPNLR----------------------------FEIVDGTDFYITPEGFILMAKAVTPG----------------------------------------------------------------------------------------------------------------------TVNLEMRVIDTEND-------------------ESSTASLVVEITPGVP----TTTPVTTITTTDNTDSTQLTDITDTS----------------------------------------------------------------------------------HPSTHTTTHPGTYTTAHP-------------------------------------------------------------------NTG-------------GQLGKAGDFTSGDMAAVG---------ATLAVFVVICLVCIGLLAHRIKGHNAAWK--------------------KLSEASIFRSTLGG---------------------------------------------------------------------------------------------GSGGPKEGMQYINESFQNDGDTP------------------------------------------------DNSRFAADLENKLEPEQSGTSQEKIT-------RSAFLQTNSKPPADSSS---------LADSEN--------------TDGEKEVKPILTKERRTDE--GYKSVWFR-----EDIDPDTKEEVVIIPDTGEADGDHEDDEDDDSEEDDEDDLRTDMDLEDDDRLTSM-----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJB6-1", "uniprot_id": "CADN2_DROME", "id": "Q9VJB6-1", "name": "Putative neural-cadherin 2", "aln": "MVDPLKIFWVLTNSTYLVTKFVRIGIADKNDSPPYFDRFLYETEIDENADLQSTVLTVNAKDHNESTNIRYQITGGNIGNAFAVQNTTGVIYVASPLDYETRPRYELRLEATRNRKNNYTTVVINVRDVNDNPPVFDRQTYRTQITEEDDRNLPKRILQVTATDGDVDRPINIVYFLTGQGIDPDNPANSKFDINRTTGDIFVLKPLDRDQPNGRPQWRFTVFAQDEGGEGLVGYADIQVNLKDINDNAPQFPQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNAKLIYSIEKNVIEEETGAPIFEIEPETGLIKTAVCCLDR-ERTPDYSIQVVAMDGGGLKGTGTASIRVKDLNDMPPQFTKDEWVTEVDETNGTYIPETPILTVTVQDEDETNTFQYKVVPNSGFGADKFAMVRNGDGTGSLKIIQPLDYEDPLQSSGFRFRIQVNDKGDDGPGGSDKYHVAYSWVVVKLRDINDNVPKFDREHIEVSIYEDTKVGTILEQFKATDADQGGHSKVAYKIVRSTNRKRQFAISDRGAVSIQRPLDRETQDRHHIQILAIDDGSPARTATATLTVIVKDVNDNAPTFAQDYKPTLPENVSGKKILEVAAKDPDDRLRGNGGPFTFRLDPLASDEIKAGFKVEYDRRGDNENGVAIISSLRPFDREAQKSYAIPIEIKDNGAPAMTGTSTLTVTIGDVNDNKMQPGSKSVLVYNYQGQSQDTPIGRVYVNDPDDWDVPDKKYYWEVQEHQRFKLDTDTGILTMRAGTRRGRYQLRFKVYDREHGQEDIPANLSVTVRDITAEAVQQAGSMRLSHITDEDFVRTWNPVKNQVEPSKLERFRNKLAELLYTDRDNVDVFSVQLKEGSPYPLTDVHFAARSATQQPYFKAVRLNGVVQMHREEIEKDVGLNITMVNINECLHEGKGKCGSNSCTSKVELGKKPYTVSVNRTALVGVRLDISAQCVCRARNFTHQDHNCRTHLCYNGGRCVETRNGPKCVACPVGYNGPRCQQSTRSFRGNGWAWYPPLQLCQESHLSLEFITRVADGLILYNGPIVPPKPEETVISDFIALELEQGYPRLLIDFGSGTLELRVKTKKTLDDGVWHRLDIFWDTENVRMVVDFCRTALVSEMEDGTPPEFDDNACQARGQIPPFAESLNLNQPLQLGGLYRQHFDQTLYNWQYAFSSKGFDGCIRNVIHNSEHYDLAFPALARNSFPACPQTDEVCLKTEHTARCWEHGNCVASLVQAKCHCQPGWMGPGCNVPTIPTTFKAQSYVKFALSFEPDRFSTQLQLRFRTREQGGELFRVSDQHHREYAILELRRGHLQFRYNLNSMRNEEQLLTLTAIAVNDGQWHVIRISRYGSAALMELDGGESRRYNESFHFTGHQWLTIDKQEGVYAGGKAEYTGIKTFEVQSDFQRSCLDDIRLDGKHLPLPPAMNGTQWGQATMARNLERNCPSNRPCSNVICPDPFDCVDLWNEYECTCSEGRIMSSDTKGCVDRNECLDLPCLNGATCINLEPRLRYRCICPEGYWGENCELVQEGQRLKLSMGALGAIFVCLIIILILALIFVLYSRKRKTTKKKKRSGPEKDVRETVISYEDEGGGEDDMTAFDITPLQIPISAQGGPPDIAACKMPIIYPVMTLLPPGQELNVAYLMEERKQRIDKDNNAPPFDDLRNFTFEGSGSIAESLSSLASGTDDENQDFNYLQNWGPRFNALAAMYVHDKAKASSQLPSDGGGGSGDGPGPGASSSSPLGGGGTGGGSGIPGNVLAVVATGSGAGPGGGGGSSGLMPLPEVDKVVL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : .. . ::: * . : : . : .: . . * :: : *: .. : . : . . : : *:** .*.* .*.* . . : . * * : : * : * : : : : **: . . : : ..*. .. ::*****:.: : ..* * * . ...* : * : . : . :. : *. . : * :. . * :*: .: : * : . : *. * . : . . . :::: . * : : : : : :. .:.. .* . . : : :: . . . .* . . * * . : . . .: . : . . : : .: * :: * * . . . . : .: : : .* * : . . . . ... .. . . . . ", "identical_positions": 44, "similar_positions": 167, "identity": "2.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110601-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q0E9H9-1", "uniprot_id": "DSCA1_DROME", "id": "Q0E9H9-1", "name": "Cell adhesion molecule Dscam1", "aln": "-------------------------------------------MNMPNERLKWLMLFAAVALIACGSQTLAANPPDAD-QKGPVFLKEPTNRIDFSNSTGAEIECKASGNPMPEIIWIRSDGTAVGDVPGLRQISSDGKLVFPPFRAEDYRQEVHAQVYACLARNQFGSIISRDVHVRAVVAQYYEADVNKEHVIRGNSAVIKCLIPSFVADFVEVVSWHTDEEENYFPGAEYDGKYLVLPS-GELHIREVGPEDGYKSYQCRTKHRLTGETRLSATKGRLVITEPVSSSPPKINALTYKPNIVESMASTAILCPAQGYPAPSFRWYKFIEGTTRKQAVVLNDRVKQVSG-TLIIKDAVVEDSGKYLCVVNNSVGGESVETVLTVTAPLSAKIDPPTQTVDFGRPAVFTCQYTGNP----IKTVSWMKDGKAIG--------------HSEPVLRIESVKKEDKGMYQCFVRN-DQESAEASAELKLGGRFDPPVIRQAFQEETMEPGPSVFLKCVAGGNPTPEISWELDGKKIANN---DRYQVGQYVTVNGDVVSYLNITSVHANDGGLYKCIAKSKVGVAEHSAKLNVYGLPYIRQMEKKAIVAGETLIVTCPVAGYPIDSIVWERDNRALPIN---RKQKVFPNGTLIIENVERNSDQATYTCVAKNQEGYSARGSLEVQVMVPPQVLPFSFGESAADVGDIASANCVVPKGDLPLEIRWSLNSAPIVNGENGFTLVRLNKRTSLLNIDSLNAFHRGVYKCIATNPAGTSEYVAELQVNVPPRWILEPTDKAFAQGSDAKVECKADGFPKPQVTWKKAVGD-TPGEYKDLKKSDNIR-VEEGTLHVDNIQKTNEGYYLCEAINGIGSGLSAVIMISVQAPPEFTEKLRNQTARRGEPAVLQCEAKGEKPIGILWNMNN--MRLDPKNDNRYTIREEILSTGVMSSLSIKRTERSDSALFTCVATNAFGSDDASINMIVQEVPEMPYALKVLDKSGRSVQLSWAQPYDGNSPLDRYIIEFKRSRASWSEIDRVIVPG-----------------------HTTEAQVQKLSPATTYNIRIVAENAIGTSQSSEAVTIITAEEAPSGKPQNIKVEPVNQTTMRVTWKPPPRTEWNGEILGYYVGYKLSNTNSSYVFETIN---FITEEGKEHN---LELQNLRVYTQYSVVIQAFNKIGAGPLSEEEKQFTAEGTPSQPPSDTACTTLTSQTIRVGWVSPPLESANGVIKTYKVVYAPSDEWYD-------------ETKRHYKKTASSDTVLHGLKKYTNYTMQVLATTAGGDGVRSVPIHCQTEPDVPEAPTDVKALVMGNAAILVSWRPPAQPNGIITQYTVYS--KAEGAETETKTQKVPH--YQMSFEATELEKNKPYEFWVTASTTIGEGQQSKSIVAMPSDQVPAKIASFDDTFTATFKEDAKMPCLAVGAPQPEITWKIK----GVEFSANDRMRVLPDGSLLIKSVNRQDAGDYSCHAENSIAKDSITHKLIVLAPPQSPHVTLSATTTDALTVKLKPHEGDTAPLHGYTLHYKPEF-GEWETSEVSVDSQKHNIEGLLCGSRYQVYATGFNNIGAGEASDILNTRTKGQKPKLPE-KPRFIEVSSNSVSLHFKAWKDGGCPMSHFVVESKKRDQ---IEWNQISNNVKP-DNNYVVLDLEPATWYNLRITAHNSAGFTVAEYDFATLTVTGGTIAPSRDLPELS--AEDTIRIILSNLNLVVPVVAALLVIIIAIIVICILRSKGNHHKDDVVYNQTMGPGATLDKRRPDLRDELGYIAPPNRKLPPVPGSNYNTCDRIKRGRGGLRSNHS----------------------------TWDPRRNPNLYEELKAPPVPMHGNHYGHAHGNAECHYRHPGMEDEICPYATFHLLGFREEMDPTKAMNFQTFPHQNGHAGPVPGHAGTMLPPGHPGHVHSRSGSQSMPRANRYQRKNSQGGQSSIYTPAPEYDDPANCAEEDQYRRYTRVNSQGGSLYSGPGPEYDDPANCAPEEDQYGSQYGGPYGQPYDHYGSRGSMGRRSIGSAR--NPGNGSPEPPPPPPRNHDMS--------------------NSSFNDSKESNEISEAECDRDHGPRGNYG-------------------------------AVKRSPQPKDQRTTEEMRKLIERNETGPKQLQLQQANGAGFTAYDTMAV--", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "M9PHS6-1", "uniprot_id": "M9PHS6_DROME", "id": "M9PHS6-1", "name": "", "aln": "-------------------------------------------MDLHS-------LFKAILILYVIRAETSQFVNGLD-LQGPIFLHEPPHRVEFSNNSGGLIECSGHGSPPPEVEWTP-----IPPQQDMVFQLSNGSMMFYPFTAEKYRHEVHATVYRCKLRNLVGTVLSREVHVRGVVNQKYAVQVHDEYVMTGNTAVLKCQVPSYMSEFVLVTAWVQDTGMHLYPNTDIGGKYTVLSN-GELYINNAGPNDAYKSYTCRTVNRLTGEVQISTYPGRIIVTEPKGMVQPRINVEKHSMRHVVLNGQTTLPCIAQGHPVPTYRWFK--EENEQLLPLQLSERITIVSAGLLKITKARLEDSGKYLCWVNNTAGEETIQVSLTVTAPLTAHLQPQVQTVDVDKDAQFQCIVSGHP----VHDVNWLHDGKPILRDNRVEI------LTDPPRLIIKKVQKEDPGMYQCFVSN-EWEQIQSTAELQLG--DASPELLYWFSEQTLQPGPTVSLKCVATGNPLPQFTWSLDGFPIPDS---SRFLVGQYVTIHDDVISHVNISNVKEEDGGEYTCTAQNAIGKVSHSAKVNIYGLPYIREMPKITGISGSDLIVKCPVAGYPIDKIHWERDGQTLPIN---RRQRAYNNGTLIIEQLQRLEDAGTYTCMAQNKQKQTSRRNVEIQVLVPPKIMPIQAMTNMLREGMRAAISCQILEGDLPVSFRWERNGKPLIGTGN-EVFRRLDEYSASLVIEHISSDHSGNYTCIASNVAGTERFTVPLTVNVPPKWILEPKDSSAQAGADVLLHCQSSGYPTPTITWKKAIGP-TPGEYKDFLYEPTVQLFPNGTIFFKKISKESQGHFLCEAKNNIGSGVSKVIFLKVNVPAHFQTKTKQISVAKGKQVHVQCNVQGDNPIDFKWKIQATQQYLDESLDSRYTIRDQVLDDGMVSELGISHTYRQDTGIYICQASNAFGQDEMSIQLIVQEVPEQPKNLRINSQQSRSLQLTWSQPFAGNSPIEEYHIYYKQISDIWQNAEHLTIAG-----------------------AQTVINIQQLRPAKAYHIRMSAENKLGASEFSEVVQVTTLEEVPSGPPLAVRAEPKSSTEIFVTWDAPERDHWNGILLGYYVGYQMSLTPEDKEVNPTQGFSFKTVEVRSHFGGETVLANLNKFTQYHVIVQAYTSQGSGPPSKEIAVQTMEDVPSSPPESPQCDVLGSTSIYITWSPPDIDGQNGKIKGYKVFYISVDELY--------------ETDPEVVKSTNQYVTIENLRKYTNYTVWVLAYTKVGDGMKTKPFYCRTHEDVPSAPQAIKAIPASSSKIIISWLPPDLPNGDITGYTFYMSMLEGGREEGTHKRLLGP--FVEMHETVRTQESATYQFWLTASTKMGEGEKTQVVTVPPNNKVPARIVSFSQRIVTPWKEHLELPCRKVGAPAPVTIWRQD----GHNMETSARKTIAKNGTLYMKECQASDAGNYTCSVENTWGKDEIVYNIVVKVPPEAPNLTVINAYTDSLLLEWMDNSHGGSPILGYVINYKRDN-GDWEELQVDSKTTSHLLTNLWCGTRYQLYITAYNKIGTGLPCDIVNSYTKGNPPVQPK-HSQMITNNSTSVTCWLDSWGDGGCGILYFMIESRVYGR---SSWAVVSNHIPPTERIYTVSDLVPGTKYQLKVTAHNNAGSTTAIYNFTTLSTQGVIYNNDHSTPVSH--LSDLP--FYANFKLLLPICFSLLMLLALIGAALFLR-KRKLASQARLASSSMSESPSLANLQNKQNRDQQYLA--------------------------VRCNPG----------------------------TSAPRGSN-----------SNDSGSFGKAEGN--------EYIEDICPYATFQLN---------KQTYSESSYSGNVYSGPYHSVRGSFVYH----DVKPESYHSKEPEYTKVRRK--VGRLRDPHSESQESDNPG--STDSEVRKILTLHIPITEYDTLGSESDNDVSARALNSAKYRAQRDTQDETSSSSETTPTSMTRKSKPPFA--ARKGGKPGTSG---KRHVRS--------------------SSGYSSHNEETTFSISNYPPNY--QDHIN-------------------------------PPARFSDANDKTKTQTSPRMRANQKLHREAFQINV----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VS29-1", "uniprot_id": "DSCL_DROME", "id": "Q9VS29-1", "name": "Cell adhesion molecule Dscam2", "aln": "-------------------------------------------MWISSR--------FFVILLLLNLDNTCSEPFEAH-LRGPGFVMEPPGRVEFSNSSGGWLDCSASGSPQPTVDWVHADGSAVTEIHGVRRVLRNGTLVLMPFAAAAYHQDVHNTIYRCIASNSVGRIVSRDVQVRAVVAQAYKVDVEVLSAARGCTAILRCVVPTFVKELVRVVSWVHEPAIYIYPSLQGDGKFHLLPT-GELLIHNLQESDESQSFRCRSMHRLTRQVVVSSPT-RLRINSHRGIISPSVVEHTAHVQVSQDEG-AVLLCVAQGCPSPEYSWFT--HNGAGPLPVLSGPRVRLLGP-ILAIEAVTGEDSGVYKCTAGNVGGEASAELRLTVATPIQVEISPNVLSVHMGGTAEFRCLVTSNGSPVGMQNILWYKDGRQLPSSG-----------RVEDTLVVPRVSRENRGMYQCVVRRPEGDTFQATAELQLG--DAPPVLLYSFIEQTLQPGPAVSLKCSAAGNPTPQISWTLDGFPLPSN---GRFMIGQYITVHGDVISHVNISHVMVEDGGEYACIAENRAGRVQHAARLNIYGLPYIRLIPKVTAVSGETLNLKCPVAGYPIEEIHWERGGRELPDD---IRQRVQPDGSLTISPVQKNSDSGVYTCWARNKQGHSARRSGEVTVIVPPSIEPFAFQEGLAEG-MRTRTVCGVSRGDPPLKLIWLKDGDPLPDLLG-ANVTMLDQYSSLLSIPSLSATHSGEYTCVAKNPAAEIKYTALLQVKVPPRWIVEPVDANVERNRHIMLHCQAQGVPTPSIVWKKATGS-KSGEYEEVRERPFTKLLGNGSLLLQHVKEDREGFYLCQANNGIGTGIGKVIQLKVNSSPYFSSTSRSVMVKKGDTALLQCAVSGDKPINIVWMRSG-KNTLNPSTNYKISVKQEATPDGVSAELQIRTVDATDSGPYFCRASNLYGNDQQLVQLQVQEPPLPPSVLEAAMISSRSVNIKWQPKTLGTGDVTKYIVEFREADPLFVDQWQQIEVKDP---------------------PHFNAMIENLKPATRYAFRVIAEGSAGRSAPSQELIVRTEPQRPAGPPLSLSARPLSSTELLISWVAPLPELRHGDIQGYNVGYKLSSSGNTAYNFTSVS------GDGDGGNGELLLSGLAKFARYTVVVQAFNQVGPGPLSEPTAAQTMEDVPSRPPEDVRCAALSSQSLQVSWQPPPIYHTNGLLQGYKLIFEPIIDDIQP-----------SKDEVESRKTTALTMVLTGLRKYTNYSIQVLAHTRMGDGVVSKPLFCHSEEDVPEAPADIKVVSSSSQSLYISWLPPNEPNGVITKYSLYTRVVNGREELNNEKRSLPS--QQAYYEAKGLHPHMEYQFWVTASTRVGEGKSSRVSSQITTNRIPARIISFGGPVVRPWRSTVTLPCTAVGKPKREWFKSDV----ALRQGGLHNSQLLDSGDLIISSLQLADGGNYSCQVDNGIGTDRLTHTLIVQVPPTAPVLYVTSATSSSILMHWKCGFTGNAPITGYTLFYRRAN-GNTDEMQLSRHASSHELKGLMCGSTYQIHLSAQNKVGTSPTSTILHVRTQGQSPGHPA-STALLAPNSTSLLVRLHSWPDNGCPLLYFVLQYRAVTDDPDAEWVLVSNALKP-QRRIVINNLQPSTLYQLRMEAHNVAGISQAEFNFVTLTKDGDPPPP--EIMHRG--RSGQTTVIFANINLLIPTIAAVSGMFCTIIMIIVCYRHMLKNAPPLAEQSQIQKESLENRANSEAAQRERYYATIHKVSMQNNDKIPETSEDISPYATFQLSEAGGN---MSQPHHGGPANTLLHSFMYHERALAEGCSSPPPAAVLNPPTTTTHHHHHHQRPLKTIHNYYQTSPFHNISKNRRRHSRKTEPESEESESDQDQLTSSRTESSNQHEGKIKHSIIYHG-AQSSTSSDLSPMSEQKSLPRRGRSRYHHQQYQFSTNTTPRHHNSNKMNNNTTSNTNTTATNTTATPSTSSNSNKILSPRGGNLKSISSTFKSQDSIQCHIPTLVKSPSISTQQ--QKQFHKQQLQNSSTNNSQHS--------------------SSNPNSSSLKQQQPLLITPKLHQLEANGQELLGLDGIGNSPLVACMPPSSQFRPIPHKSIMPAHEPPHHHNHSQQSHPHQQQQQQQHPGTLLNPSTAMLSSKFFTAPTLPK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q7KSE9-1", "uniprot_id": "Q7KSE9_DROME", "id": "Q7KSE9-1", "name": "", "aln": "---------------------------------------------MSLLEPPCLVLEKALLLGALLLAVLATPLLATSGLRVPTFLLEPAPRLLFGNDTGAQVTCTAHGSPPPLVTWVLRDGSLATQVPGLRKISGNGTLHFPPFLAQYYRTDVHEATYRCRASNEAGTVLSRNVQVHAVVRRQFHVHVENTEVYLGNSALIKCAIPEYVRPYVRVASWHRGEEILLPDLSDVAGRYVVLAASGDLYVRSVRSEDGLMKFSCLVTNTLNGERQR-SDAVMLQVKELSKNLAPRTTQKPVMEIHVERGNDVHLPCNIQGNPFPIFTWYR--VSDSAALYPIPSSQRVILSRTLLLIKNADERDAGKWICQASNQFGEQRIEIRLSVNSYVSVHILPQVQIVNSGGTANFNCTTTGSA----IDAIDWLHNGKPLQANNALTTGRDNIRFLSKSSLLVQNVGRRDRGVYQCLVEN-QRASAQAMAELKLG--DTVPELIYTFIEQNVRPGPLISLKCSASGSPPPQFAWLLDSQPIMDVSLHHRFAIGQFVDMSGDVISHLNISHVRPDDGGLYKCVASNSMGSVQHSARLNVYGPPYVRAIGPIKAVAGEDIIVHCPFAGYPVEQIRWEKAHQELTTSNHYELASVADGGQLVIKNVEPGRDQGIYTCIVRSRAGEEARRDMQLNVNSPPVIEPFKFPKNLQEG-GRAQITCAVSSGDMPIYFSWKKDDSSIPSSLQ--ITEKKEEFYSLLVFKDISARHSGKYTCYASNAAAKVNYTAELQVRVAPRWRYEPMDTAIMLGNTISINCEAEGYPIPTITWFKGQGK-GSKDFKPLSMR-------NHSLLLNLATDNDEGYYMCQATNEIGAGLKKTIRINVNEPARFEQSARNISSRRNDPVTLDCHAKGDEPITIGWTQNNGRIDLN---NFRFSIAEMKTEKGVDSQLTIGHSDRHDSGVYRCIAENPYGRAEQIIFLAVQERPDTPSHLEIFEVGSRTVKLSWRRPFDGNSPVLSYLVQYQALKYLQSHGSLAAAGGDWNGHVINVSLPSTSISRSYDSDLRESAIVAGLTPATTFLIRMQAINEIERSAYTEAIVLKTQEEAPTEAPSNVQVQTGGESELIVTWQIPPRESWNGELIGYTVNCSEEKQNINFISVVNSS--LKSTIVSGWATTKATLRGLRKYSRYAVTIRAMNSFGSGPWSAAIFGTTAEGVPEAAPQNVNCTALSSQSLKISWLEPPLQFHGGIIQGYKILYRPIVHQID------------FPAKLEIKRTSNLETYLHTLHKASNYSIRVLAYTATGDGLASHPLFCQTDDDVPDAPAAIKAAALTADSILISWLTPKNRNGIISHYTVYSREAGRKGQAKTHMVRVDENGYPVTFESRSLAENQMYEFWVSASTSVGEGEPTSVIAQATNTRAPARIASFGQVVRKAVGTGLVLECLAVGNPTPRARWLTR----DRPVTFSPFYEVTNEGNLKIHRVEGSLSGNYTCTANNLFGSDEIQYQVIAMKPPSAPQIIVQYASADSIRVSWDAPDDGGAPLQGYTISYHTAG-ESWSITELLPENNAFTISGLKCGNQYIIKMSAHNMVGSGVASEEINVWTKGKASQAPN-ANELIATNATCVNLKLSSWQNGGCSIHHFSIEHRPLGDIRWTVVTSDISNAEENRENLIFCDFLPAKWYQLRISATNDAGKTTEHYHFSTTNIDGITIPPPSVFPSENDLMNNLINSTNPTSGDWFATLIVVVIITVSIITIALTIKHRRTLCGPIAEGYESRTLPGDYKEDHENRRNQQVYSASPVKTVDKGNESEMYEISPYATFSVNGGRTG--------APAKTPTRAVAAQTPLDYTMQFKTFGHPEGENLNATAYPLLPSSGFGHVKSKSSWHKQRYYNTEDESTLSKSMTIVAGSQAGHSKKSNGGRSAKSSAACSGVVAGSESDTSISPSTEFSNMPTYRVPCKSSRSSDGRAVVDMFRPDSSTESNNDQGSPAPERRHNTPRHVLGMGMAMGLGGGGGGGVGGGNGPAEKRSAGQRSRKHGSAAQQPSNQTLERRKCPGSSNSLDSEVDAETAASLAASIAAMA--------------------GSGAGADLSGGFRPPAGFHDGREPGDHSDCE-------------------------REQRALDLEVQRVMESTGDAQLAKMDREELTSLLARYHEKKEQERLEYTIHV---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "D3ZPL7-1", "uniprot_id": "D3ZPL7_RAT", "id": "D3ZPL7-1", "name": "Cell adhesion molecule DSCAML1", "aln": "MTGAGEPRREEPPPCAGLRSRESGAPSAGGWERAERGRGAAARPATGPPPRRKGPLYGMWLVTFLLLLDSLHKARPEDVGTSLYFVNDSLQHVTFSSSVGVVVPCPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGTLQLYPFSPSAFNSFIHDNDYFCTAENAAGKIRSPNIRIKAVFREPYTVRVEDQRSMRGNVAVFKCLIPSSVQEYVSVVSWEKDTVSITPENR------FFITSHGGLYISDVQKEDALSTYRCITQHKYSGETRQ-SNGARLSVTDPAESIP--TILDGFHSQEVWTGHAVELPCAASGYPIPAIRWLK-----DGRPLPADSRWAKRITG--LTISDLRTEDSGTYICEVTNTFGSAEANGVLTVIDPLHVTLTPKKLKTGIGSTVILSCALTGSP----EFTIRWYRNTELVLPGEAISIRG-----LSNETLLISSAQKSHSGAYQCFATR-KAQTAQDFAIIVLE--DGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPVVRD---GSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNSVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDN---HRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPP--ASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISG-SGVTIES-KEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKAMFLTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDN--GDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPP-ELEIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNISP----------------------TINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNGIIRGYQIGYRENSPGSNGQYSIVEMK-------ATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDG-------------EWGEMQNVTTTRERVELRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASSVVVSWLPPTKPNGVIRKYTIFCSSPGSGQPAPSEYETSPE---QLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWLKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSLDGHRLIHTNGTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPDQPRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQYSVDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTHGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITAIVLEYRPKGTWAWQGVRANS------STEVFLTELREATWYELRMRACNSAGCGNETAQFATLDYDGSTIPPIKSAQGEGDDVKKLFTIGCPVILATLGVALLFVVRKKRKEKRLKRLRDAKSLAEMLIS-KNNRSFDTPVKGPPQGPRLHIDIPRVQLLIEDKEGIKQLGDDKATIPVTDAEFSQAVNPQSFCTGVSLHHPALIQSTGPLIDMSDIRPGTNPVSRKNVKSAHSTRNRYSSQWTLTKCQASTPARTLTSDWRTVGSQHGVTVTESDSYSASLSQDTDKGRNSMVSTESASSTYEELARAYEHAKLEEQLQHAKFEITECFISDSSSDQMTTGTNENADSMTSMSTPSEPGICRFTASPPKPQDADRGKNVAVPIPHRANKSDYCNLPLYTKSEAFFR-KADGREPCPVVPPREASMRNLTR-AYHTQARHLTLDP--------------------ASKPLGLPHPGATAAT----ATATLPQRTLAMPAPPAGTAPPAPGPTPSEPSAPPSAAPPAPSTEPPRAGGPHTKMGGSRDSLLEMSTPGVGRSQKQGAGAYSKSYTLV--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q4VA61-1", "uniprot_id": "DSCL1_MOUSE", "id": "Q4VA61-1", "name": "Cell adhesion molecule DSCAML1", "aln": "----------------------------------------------------------MWLVTFLLLLDSLHKARPEDVGTSLYFVNDSLQHVTFSSSVGVVVPCPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGTLQLFPFSPSAFNSFIHDNDYFCTAENAAGKIRSPNIRIKAVFREPYTVRVEDQRSMRGNVAVFKCLIPSSVQEYVSVVSWEKDTVSITPENR------FFITSHGGLYISDVQKEDALSTYRCITQHKYSGETRQ-SNGARLSVTDPAESIP--TILDGFHSQEVWTGHSVELPCAASGYPIPAIRWLK-----DGRPLPADSRWAKRITG--LTISDLRTEDSGTYICEVTNTFGSAEANGILTVIDPLHVTLTPKKLKTGIGSTVILSCALTGSP----EFTIRWYRNTELVLPGEAISIRG-----LSNETLLISSAQKSHSGAYQCFATR-KAQTAQDFAIIVLE--DGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPVVRD---GSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNSVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDN---HRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPP--ASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISG-SGVTIES-KEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKAMFLTVKIPAMITSHPNTTIAIKGHPKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDN--GDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPP-ELEIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNISP----------------------TINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMK-------ATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDG-------------EWGEMQNVTTTRERVELRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASSVVVSWLPPTKPNGVIRKYTIFCSSPGSGQPAPSEYETSPE---QLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSLDGHRLIHTNGTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPDQPRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQYSVDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTHGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITAIVLEYRPKGTWAWQGVRANS------STEVFLTELREATWYELRMRACNSAGCGNETAQFATLDYDGSTIPPIKSAQGEGDDVKKLFTIGCPVILATLGVALLFVVRKKRKEKRLKRLRDAKSLAEMLIS-KNNRSFDTPVKGPPQGPRLHIDIPRVQLLIEDKEGIKQLGDDKATIPVTDAEFSQAVNPQSFCTGVSLHHPALIQSTGPLIDMSDIRPGTNPVSRKNVKSAHSTRNRYSSQWTLTKCQASTPARTLTSDWRTVGSQHGVTVTESDSYSASLSQDTDKGRNSMVSTESASSTYEELARAYEHAKLEEQLQHAKFEITECFISDSSSDQMTTGTNENADSMTSMSTPSEPGICRFTASPPKPQDADRGKNVAVPIPHRANKSDYCNLPLYTKSEAFFR-KADGREPCPVVPPREASMRNLTR-AYHTQARHLTLDP--------------------ASKPLGLPHPGATAAT----ATATLPQRTLAMPAPPAGTAPPAPGPTPSEPSAAPSAAPPAPSTEPPRAGGPHTKMGGSRDSLLEMSTPGVGRSQKQGAGAYSKSYTLV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TD84-1", "uniprot_id": "DSCL1_HUMAN", "id": "Q8TD84-1", "name": "Cell adhesion molecule DSCAML1", "aln": "----------------------------------------------------------MWLVTFLLLLDSLHKARPEDVGTSLYFVNDSLQQVTFSSSVGVVVPCPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGTLQLYPFSPSAFNSFIHDNDYFCTAENAAGKIRSPNIRVKAVFREPYTVRVEDQRSMRGNVAVFKCLIPSSVQEYVSVVSWEKDTVSIIPEHR------FFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQ-SNGARLSVTDPAESIP--TILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLK-----DGRPLPADSRWTKRITG--LTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSP----EFTIRWYRNTELVLPDEAISIRG-----LSNETLLITSAQKSHSGAYQCFATR-KAQTAQDFAIIALE--DGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRD---GSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDN---HRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPP--ASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISG-SGVTIES-KEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTTIAIKGHAKELNCTARGERPIIIRWEKGDTVIDPDRVMRYAIATKDN--GDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLIQLTVQEPPDPP-ELEIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQSTRNISP----------------------TINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMK-------ATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDG-------------EWGEMQNITTTRERVELRGMEKFTNYSVQVLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASSVVVSWLPPTKPNGVIRKYTIFCSSPGSGQPAPSEYETSPE---QLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPDQPRLTVSKTSASSITLTWIPGDNGGSSIRGFVLQYSVDNSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTHGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITAIVLEYRPKGTWAWQGLRANS------SGEVFLTELREATWYELRMRACNSAGCGNETAQFATLDYDGSTIPPIKSAQGEGDDVKKLFTIGCPVILATLGVALLFIVRKKRKEKRLKRLRDAKSLAEMLIS-KNNRSFDTPVKGPPQGPRLHIDIPRVQLLIEDKEGIKQLGDDKATIPVTDAEFSQAVNPQSFCTGVSLHHPTLIQSTGPLIDMSDIRPGTNPVSRKNVKSAHSTRNRYSSQWTLTKCQASTPARTLTSDWRTVGSQHGVTVTESDSYSASLSQDTDKGRNSMVSTESASSTYEELARAYEHAKLEEQLQHAKFEITECFISDSSSDQMTTGTNENADSMTSMSTPSEPGICRFTASPPKPQDADRGKNVAVPIPHRANKSDYCNLPLYAKSEAFFR-KADGREPCPVVPPREASIRNLAR-TYHTQARHLTLDP--------------------ASKSLGLPHPGAPAAA----STATLPQRTLAMPAPPAGTAPPAPGPTPAEPPTAPSAAPPAPSTEPPRAGGPHTKMGGSRDSLLEMSTSGVGRSQKQGAGAYSKSYTLV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B4A1-1", "uniprot_id": "A0A8M2B4A1_DANRE", "id": "A0A8M2B4A1-1", "name": "", "aln": "----------------------------------------------------------MWLVTLLLLYSFQEVHSEDVVSTRLYFVNASLQRVTFSSSVGVSLPCPAGGAPHAVLRWYLATGDDIYDVPHIRHVHANGTLQLYPFSPSAFNSFIHDNDYFCTAENQAGKIRSPSIRVKAVFREPYTVRVADQRSMRGNVAVFKCLIPSAVQEYVSVVSWEKDTVSIVPGNR------FFLTSYGALYISDVQKEDALSTYRCITKHKYSGETRQ-SNGARLSVLDPTESTP--SVMDSFQSGEVQVGRSIELPCIASGYPNPTIRWLK-----DGRPLPADSRWTRRLTG--LTISDLRLEDSGNYICEVTNSFGSKEVTGHLNVIEPLRVTLSPKNLKTGISSTVILSCAVQGSP----HFTVSWFRNTEPIVPDQHFSIQG-----AHNETLFITAAQKRHSGAYQCFATR-KGQTAQDFSIILLE--DGTPRIVSSFSERVVAPGEPFSLMCAAKGAPPPTITWTLDDEPVARD---SAHRASQYTLSDGSTVSHVNVTNPQIRDGGVYRCAARNSAGSAEYQARINVRGPPSIRAMRNITAVAGRNTFINCRVIGYPYYSIKWYKDGMLLPDN---HRQVVYENGTLKLSDVQKGMDEGAYLCSVLIQPQLSISQTVYVTVKVPPLIQPFDFPP--TSIGKLMYIACVVSSGDMPIRITWRKDGQEIVSGTAGVTIET-KEFMSSLQISKVSLKHNGNYTCIASNDAATVSSERQLIVTVPPRFRVQPNNQDGIYGKSEVLNCSVEGYPPPKVVWKHAKGIGNPQQYHPVPLTGRIQILSNGSLLIRHVLEEDRGYYLCQASNGVGSDISKSMMLTVKIPAMITSHPNTTMAIKGQNKELNCTARGEYPIIIRWERGDTVIDPDRNPRYSITTSPNEKSDEVISTLKLKPAERGDSVFFSCHAINSYGEGRGLIQLTVQEPPDPP-ELEVREVKDRSMNLRWTQRFDGNSIITSYDIEYKNKSDPWELKHATRKISP----------------------TNNQANIVELHPASVYSIRMYSYNKIGRSQASKELTISTEEAPPDGPPMEVILQPMTSQSIRVTWKAPKKELQNGVIRGYQIGYRENGPGSNGQYSIVEMK-------ATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPQNVRAITVTSDEAVITWSEPPRMTLNGVLKGYRVVFWSLYPDGGGCCGGQTLGLNQKWGEMQNITTTREQVELKGLEKFTNYSVQVLAYTQAGDGVRSNVLYIQTREDHPGPPAGIKAVPSSASSVVVSWLPPVKPNGIIRKYTIYCSSPGSGQPAPSEYEANPE---LLIYRITHLTRGQQYLIWAAAVTTAGRGNISEKVTVEPAGKAPAKILSFGGTVTTPWMKEVRLPCSSVGEPTPTIKWTKDSEDTAIPVTQDGHRNILSNGTLVLRSVKAEDSGYYTCTATNTLGFDTIIVNLLVQVPPDQPRLTVSTTSTSSITLAWIPGDNGGSSIRGFVLQYSVDNTEEWKDVFISSSERSFKLDNLRCGTWYKVKLAAKNSVGAGRISEIIEAKTHGREPQFNKDQPLFTHINSTHARMNLQGWTSGGCPITAVLLEFRPKGTWAWQSVRTNA------SADIFLAELREATWYELKMKACNSAGCGNQSSQFATLDYDGSTIPPIKSARGEGDDVKKLFSIGCPVILVTLGMALLFIIRKKRKEKRLKRLRDAKSLAEMLISSKNNRSFDTPVKGPPQGPRLHIDIPRVQLLIEDKEGIKQIGEDKATIPVTDTEFSQSVNPQSFCTGVSVHHPALIQNTGPLIDMSDIRPGTNPVSRKSVKSAHSTRNRYSSQWTLTKCQASTPARTLTSDWRTVGSQHGITVTESDSYSASLSQDTDKGRNSMVSTESASSTYEELARAYEHAKLEEHLQHAKFEITECFISDSSSDQMTTGTNDNADSMTSMSTPSEPGICRFTASPPKPQDYDRGKNVAVPIPHRANKSEYCNLPLYMKTDPFFRKQAELHDPCPVVPPREASIRSLAARAYHTQGRHMTLDPSKQQALTLGHGGLSSLTSSGASGTSGPPSSGAAGSSSISSGTATLPQRTLTMPSTSSTSSAPSG-------AVAAGAGASASSTGGSGPTPGSSKVGGSRDSLLESSSSGLGRLQKQNAGAYSKSYTLV--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: . :: *... * : * . * * . : * : :*.: : ** . :. :* * * * * : * .::::.*. . : . * * *:::* :* : * *.:* .:. * * : . .* .: * : . : : : : . : * .* * * * . : * * .*:* : * . * * * * : . : * . . . : * . : * :: . : * : . : . * ***.. . . : : : * * : * *. : ** . * * * * * * .:* **. : . .*: . .:*::*:: *** * * * . * ..: *::*: * * :* : ::* : * . *** .* * : *. . . .* * : :: * . * * . : : * ** : *: * : ** *: : * :. : . .: : * : :. * * *.* *.* *. * * *.*:: :* : . :.*. .* * * : * :. * . ::. . : :: . . *.::*:* * :*:.: : :.*: .. : . :.. ::* . *: ** : * : : : : * : *: : * * * :* : : *** * * *. *:::: * *.. : : : :: : * **. : :*: : . * :: : : * * * : .. . : ::* * :* : ** :. . * .* :::* * ::* . *.** * * *..*. .*.. . : * : * * .* :: *::.: . . . :: : :.* :**:: *** * ***: : :. :: * * .* :*. : :** .* ** * *:.: .. .. * :* :* * *.*: : . : **:* **. . . : * ** * : .* * : : .* *:* . * . * : ::. ** * : : : :.:: : . :.: *:.: * . . : . : .* **. * : :. * :*:. . :. *:*. . : .:. : .* ..** : . :: : . :: .. *:*:: * * ** .* * * . . . . . . . . . : : . . . . . : . . . . * : . : ", "identical_positions": 248, "similar_positions": 398, "identity": "11.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110603-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8K2-1", "uniprot_id": "CCD39_RAT", "id": "D3Z8K2-1", "name": "Coiled-coil domain-containing protein 39", "aln": "--------------MSSEFLSELHWEDGFAIPVANQENKILEDQLAKLHKEKSNLQDQLRDYEDRINSMSSHLKNVNQEFLFTQSLYKARECEIESEEHFKAIAERELGRVKDEIQQLEKEMAIILERKNDKENAIFKATQKLDGLKCQMNWDQQALEAWLEESAHKDSDSLTLQKYSQQDNNKIRALTLKLEKLTMECNEKRKLLDNELTETLSAQLELDKAAQDFRKIHVERQELIQQWENTIEQMQRRDQEIDNCALALARIKQEAREKEGVVREKIKFLENEVGNNVEYERRISIAERKVSKCRMEYQRQEANRNQLKDELDTLKTTLNRTSSDLEALRKNISKVKKDILDETGRLQKLKHHNEIVKHKLKMITEKTISIEEKATNMEDMLKEEEKNLKEVEVQLNIVKGVLFKKVQELQSAITKEKALGSEIEGTRSSLKHLNQRLHKLDFETLKQQEIMYSQDFYIQQVERRMSRLKGEIN-SEEKQALEVKIVELRKTMEERKSTLSLLEEQIKKLHNDLYFIKKSNGKNKDEKESLMNKIGELHLFVDRSEKELNKAKAVKEDLMIEDNLLKLQVKRARELLYSKAEEVLSLEKRKQQLCTAMEERVEEIKVHKAMLTSQIRYVDQQRQTVSSEFHERLSKIDKLKNRYEILTVVMLPPEGEEEKTQSYYVIKAAQEKEELQREGDSLDAKISKAEKEIYALQNTLQVLSSCNNNYKQSFKKVTPSS-DEYGIKIQLEEQKRS---ADEKYRCKQRQIRELQEDIQSMENTFEVIEHLANNAREKLSEKQTLSFQLRKETEEQKPKIQRVTKQCGRLRREIRILRQTNDETLE-EQDIQLREIIQFHKDIDQMLVNAMEN-AEIHVIFQTYFQQNGLELPTAK-GPSSRSSSQSS----LSSIR--------SLEDSIPISPPTAKVIELRFPGPP-ARSDSSRSSS-GSNSNIPKGKKLNK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D5Y1-1", "uniprot_id": "CCD39_MOUSE", "id": "Q9D5Y1-1", "name": "Coiled-coil domain-containing protein 39", "aln": "--------------MCSEFLSELHWEDGFAIPVANQENKILEDQLAKLREEKSNLQDQLHDYEERINSMTSHLKNVNQEFLFTQSLYKARESEIESEEHFKAIAERELGRVKNETQLLEKEMAIIRERKSQMENNIFKTTQKLDDLKCQMNWDQQALEAWLEESAHKDSDSLTLQKYSQQDDNKIRALTLQLEKLTMEYNEKRKLLDSELTETLSAQLELDKAAQDFRKIHLERQELIQQWENTIEQMQRRDQEIDNCALALSRIKQEAREKEGVVKEKIKFLENEVENNIEYERKISVAERKVSKCRMDYQRHEGNRSQLKDELDTLKTTLNRTSSDLQALRKNISKVKKDIFDETLRLQKLKHHNEVVKHKLKMITEKTLSIEEKATNMEDMLKEEEKGLKEVEVQLGIVKDVLFKKVQELQNEIAKEKALVSEIEGTRSSLKHLNKQLHKLDFETLKQQEIMYSQDFYIQQVERRMSRLKGEIN-SEEKQALEAKILELKKTMDEKKSTLSLLESQIKKLHNDLYFIKKSNGKNNDEKESLMNKISELNLFIDRSEKELSKAKAVKEDMMIEDNLLKLQVKRARELLYSKAEEVLSLEKRKQQLGKDMEERAEEIKVHKAMLTSQIRCVEQQRKTMSSEFHERLSKIDKLKNRYEILTVVMLPPEGEEEKTQSYYVIKAAQEKEELQREGDSLDAKINKAEKEIYALQNTLQVLNSCNSNYKQSFKKVTPSS-DEYALKIQLEEQKRT---ADERYRCKQRQIRELQEDIQSMENTFEVIGHLANNAKEKLTEKQTLAFQLRKETEEQKPKLQRITKQCGRLRREIRILKQTDNETLE-EQDIQLREIIQFHKDIDQMLVNAMEN-AEIHAIFKTYFEQNGLELPTAR-GPSSRSSSQSSS---LSSFR--------SLEDVTLQSPPTAKVIQLRFPEPPPATNDSSRSASSGSNSNIPKEKKLSK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UFE4-1", "uniprot_id": "CCD39_HUMAN", "id": "Q9UFE4-1", "name": "Coiled-coil domain-containing protein 39", "aln": "--------------MSSEFLAELHWEDGFAIPVANEENKLLEDQLSKLKDERASLQDELREYEERINSMTSHFKNVKQELSITQSLCKARERETESEEHFKAIAQRELGRVKDEIQRLENEMASILEKKSDKENGIFKATQKLDGLKCQMNWDQQALEAWLEESAHKDSDALTLQKYAQQDDNKIRALTLQLERLTLECNQKRKILDNELTETISAQLELDKAAQDFRKIHNERQELIKQWENTIEQMQKRDGDIDNCALELARIKQETREKENLVKEKIKFLESEIGNNTEFEKRISVADRKLLKCRTAYQDHETSRIQLKGELDSLKATVNRTSSDLEALRKNISKIKKDIHEETARLQKTKNHNEIIQTKLKEITEKTMSVEEKATNLEDMLKEEEKDVKEVDVQLNLIKGVLFKKAQELQTETMKEKAVLSEIEGTRSSLKHLNHQLQKLDFETLKQQEIMYSQDFHIQQVERRMSRLKGEIN-SEEKQALEAKIVELRKSLEEKKSTCGLLETQIKKLHNDLYFIKKAHSKNSDEKQSLMTKINELNLFIDRSEKELDKAKGFKQDLMIEDNLLKLEVKRTREMLHSKAEEVLSLEKRKQQLYTAMEERTEEIKVHKTMLASQIRYVDQERENISTEFRERLSKIEKLKNRYEILTVVMLPPEGEEEKTQAYYVIKAAQEKEELQREGDCLDAKINKAEKEIYALENTLQVLNSCNNNYKQSFKKVTPSS-DEYELKIQLEEQKRA---VDEKYRYKQRQIRELQEDIQSMENTLDVIEHLANNVKEKLSEKQAYSFQLSKETEEQKPKLERVTKQCAKLTKEIRLLKDTKDETME-EQDIKLREMKQFHKVIDEMLVDIIEENTEIRIILQTYFQQSGLELPTAS-TKGSRQSSRSPSHTSLSARS--------SRSTSTSTSQSSIKVLELKFPASSSLVGSPSRPSSASSSSSNVKSKKSSK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CK98-1", "uniprot_id": "CCD39_DANRE", "id": "P0CK98-1", "name": "Coiled-coil domain-containing protein 39", "aln": "--------------MSSALLEEVGWDADFAIPVANAENKALEEQIRKKQKDILNLDNKLNKHKDVINALTEHLKNLKQEVSHNQALCKAKEKETESEVHLKALAERETGRLKQEITRLESQLTTLNEKKNAQENSIFKATQKIDELTSQLNWDQQTLEAFLQESAHKDEDTMAIIKYAKQDERKIKELTLNIEKLTLESNQKRKTLDNELTETVTSQIALDKTAESFRQAHTERQELISQWENTIEQMRKRDQDIQQCAMMLAELNQTIREKNDLIKERKDFLEREIENNKELERNIGTVERQAFRLRQQLQEEEKNQRRLQDEVEVLKGTVDRTATDVETSRSQLSSMKKDIQDKTTKVEEAQLHNAALEEKLRMVTEAVLNGEEQAAQMEQLLREQEQNIKEIDSQLLRQKELLFKKSQEVQALRDKEKNVTAEICATRTALSNLDSKLRKLDQNFLQQQMIISNQDFQIQMLERKTLHLQGKVN-TEEKKALEKKVADLAASLEEKKKTAANLNKQLKKLQDDIRCIKKDTEKIGAEKTNLSTKIQEVELFIETSEKERKKSRLKKQDSMVEKGLLKMEVQRLRNLLYDRADGVLTLEKRRLQLQTAMKEREEEIRVHREMLNKQVKLTEQERQGLSAAVNEAMSKIDKQRKRYEVLSVSLAPPEGEEDKSQAYFIIKAAQEKEELQRKGDELDAKIRKTEKEIHALENTLQVVNNCNSTHRKALTKVTESS-PAHQEKLKLEEQRRA---AEEKYKYKRRQTQELQEDIESMSNTLEGLLQEEKVLNEGIERTQAHVLSLNKDILSQEEKINRAVKQCAKYTKEIRSGKQSTEKTFE-ERDIELRELRDFNKSINKMLLDAMEGNPELSSILQIHFTQAGLSLPSPSSTPSSRLSSKPSSARSSASLHRSSNLSASSSPRSQSVSSPQMKTVDLGLGLSVTSPRG-SQPSSAGSSRSSSKCKSP--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN57-1", "uniprot_id": "Q9VN57_DROME", "id": "Q9VN57-1", "name": "Coiled-coil domain-containing protein 39", "aln": "MNRTDDMKNASLNDYKLEAMASVGWAVDSDIPMASAENLAILKELTALRALKLELQQHMNSLDEREMAVERHTRNIEGTIQQNLTLYSSLKDDVIKEAHNVQLVILERNKIKEDLRKNNKELEEYTEYVKVTERKICQSKREIDELTSRIKSAKTTLVEWTEAMEDGNKGYQLIEKYYLDDQQKARELNIKRQLLQADIDKRRKQVVLLYDEQMTLEKNLERTACLYRSAHAERRQMVETWKSAVNQMTQREHDIQRSEIECAELAQKAQQTAQTYKEYDNQLTEVIENNRQVELAIESLNEESSDMKNQIQILIDATLLKEREIDGLRRELENLSNRVHLQRMDNRSQMKKRDEKAKELENFASVMEKVNARLKSVQNKALNAEQRLQILEEMMQAEETALRNLDKEQEKVNEMLYRTQRQVIELQDEEKVLKVQNDSLNSNLAAINRNQQQVNNELKRQTEIHYSLSFKCLEAERRLAEIKGLADDPEVEATNMARLNTLEQEYEKLQRLIATTEAQNKKLNYNMNNLVVQYNADEKELEMVRFKIKEAQVYCEGTVKRLRQIRYENSELIVDLNMVKMRCSDLEVGIGGCEQGTYDLEQHRLAFRRAIKDRTVELRSQEDVLLLKKKHLNEELSTLRADLGERKKQIEAMKARFELTAQLLGKNEDGSIMTSTQLKVVSAQERQMLADEGDALNKKVLKAEKEVVALENTLRQFDKSNDNYRKTFRSVDENSKDRERAELELKELEAAYCRELEKLKVLRCKAQHYQQKHAAQRAEEEDLISKIEKAKASRAEHSAVLEKIERELDDQRMKLDRANREIRTQLREIKARPFSEEYLAQFERDLSLQELEARNTKALNMITDLANSDESGTDIIGILLR-KGIKLPMHLKRTCSRVSWNSSSSGKSSQGQDTASYLNVKGKKFSCDGASARSSVSDMSSLKDDTSSTTSHSGLSIISLELPLPKKK--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: * . **:*. ** : .:: : .*::.:.. .: :: * :*:: . . :* .: : : .* * :. * .::*:: :.:: * . *. * ::.:::* *..::: : :* : : . :.. : ** :*:.* : *.:: : * : :::** : * :: : *:::* :*. * **::::. *:.:::** :*: :*:.. : :.: * ::. :* . * : ** : * * :.: : * : *:: *: ::. :. :. * : . *. ::: .::: :: :*: : : .:. *:: :*:::: :* ::::: : : :*::. ::: :** : : . .: * :: . :::: : :* * . .* **: .::* : .* : : :: * :: : . : * ***: :: : * : ** * .:: : : *. : : :.: ::: .::*:. . . : . : . **::: : :::* *:: :. :* : : ::: . : : . * .:*: : *:*: : : *. . :.: : :***:: * :** *: *: *:***: **:***: ....*..::::: .* .* :::*:* . : *: : : : :. *:. : : : : . . .: .: :: .*. *::* :: :**: : : : *:*:.*:*: :. :*: : : . *: : *:.** ** * ... : . . . . :. *:.. . . *. ", "identical_positions": 131, "similar_positions": 359, "identity": "13.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110603-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M6Q7-1", "uniprot_id": "A0ABK0M6Q7_RAT", "id": "A0ABK0M6Q7-1", "name": "", "aln": "--------------------------------------------------------------------------------------MLTPMVAGGVVFPGLFLLSKNTLQRLPQ-------LRWEEADAVIVSARLVSSVQAIMASTAGYIVSTS--CKHIIDDQHWLSSAYTQFAVPYFIYDIYAMFLCHWHKHQVKGHGG----EDGTPRALGSTWAVVRG--------------------------------------YLHKEFLMVLHHAAMVLVCFPLSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKILIQYKQQHTLLHKVNGALMLLSFLCCRVLLFPYLYWAYGRHAGLP-LLSVPMAIPAHVNLGAALLLAPQLYWFFLICRGACRLFRPRGS-----PPRSPCQTQD-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TNV1-1", "uniprot_id": "TLC3B_MOUSE", "id": "Q7TNV1-1", "name": "Ceramide synthase", "aln": "--------------------------------------------------------------------------------------MLTPMVAGGVVFPGLFLLSKNTLQRLPQ-------LRWEEADAVIVSARLVSSVQAIMASTAGYIVSTS--CKHIIDDQHWLSSAYTQFAVPYFIYDIYAMFLCHWHKHQVKGHGG----EDGTPRALGSTWAVVRG--------------------------------------YLHKEFLMVLHHAAMVLVCFPLSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKILIQYKQQHTLLHKVNGALMLLSFLCCRVLLFPYLYWAYGRHAGLP-LLSVPMAIPAHVNLGAALLLAPQLYWFFLICRGACRLFRPRGS-----PPPSPCQTQD-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q71RH2-1", "uniprot_id": "TLC3B_HUMAN", "id": "Q71RH2-1", "name": "Ceramide synthase", "aln": "--------------------------------------------------------------------------------------MLTPMVAGGVVFPGLFLLSKNTLQRLPQ-------LRWEEADAVIVSARLVSSVQAIMASTAGYIVSTS--CKHIIDDQHWLSSAYTQFAVPYFIYDIYAMFLCHWHKHQVKGHGG----DDGAARAPGSTWAIARG--------------------------------------YLHKEFLMVLHHAAMVLVCFPLSVVWRQGKGDFFLGCMLMAEVSTPFVCLGKILIQYKQQHTLLHKVNGALMLLSFLCCRVLLFPYLYWAYGRHAGLP-LLAVPLAIPAHVNLGAALLLAPQLYWFFLICRGACRLFWPRSR-----PPP-ACQAQD-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5W6-1", "uniprot_id": "A0ACD6B5W6_DANRE", "id": "A0ACD6B5W6-1", "name": "", "aln": "--------------------------------------------------------------------------------------MLSIIAAGSVFFPGLFLLSKQMLRCIPG-------LQWNEGDATIVSARLVSSIQAIMASTAGYIISSS--CQDIIEDQHWLTSSYILFAVPYFVYDIYAMFLCYWHKLQVKGHEV----DNGSR----SKAMAIAG--------------------------------------YLRREFLMVLHHVVMVTVCFPVSVFWRQGKGDYIQGVMFLAELSTPSVCLGKILIQYKQQHTLLHKVNGAVMLITFFLCRVLLFPYLYYIYGRYASIP-FYLVPFSVPWQCNLGASLLMAPQVYWFSLICRGALRLFTGRSSHSRKPPVKPDCEGHETANGYSTRMVGRDTPTMAH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3S7-1", "uniprot_id": "Q9V3S7_DROME", "id": "Q9V3S7-1", "name": "TLC domain-containing protein", "aln": "MQQRRQPANGNGRGGGTTAAVRTEEQQQQQQPLSQDAGAKEAGSTPGKATGRGCYFSLAFSIGSMGLACGSLWQIPNSSDRISLQRGLVLTSLGFIYFVSLTDFCNKYLLETTHGQRFRRKYRLMMSDVLEITNKIVSAIQASFSFFVGLIVCKSTCTKSFVYASHFLMEAYGWFGTAYFMYDIWSMYKVHTQKIADKLHLLRITKGQGAVVSNGHANGKVNGKSASGNNNGSTPTNLHEICDYDGACVQIPKDGRWDFLKYVVTHPVMMIHHVFIGTFGLLVVTYIRGG-GHCIYSYMFMMEFSTPFVSLRSILSTMRLKDSRVYIANGLLMLATFFVCRVCMWPYVMWRYSLAIEAASLWSAMWGLPRGCLISIAILFLPQLYWFYLMVLGALKVFLPQKRR----PPNAVLSAKSAAVPTPTPTALINGKN---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * : * .* :.:: * . : .*. :: ::**::** :: .* *:..* : :: .*:* .:* *...**:***::*: : :* * * :*: * *: . :*::**. : . : : . * * *. : . *:: *.*** *.* .** : :.: :: .** :** :*: *** ::**: : *. . : . .:* :. ::*: **:*** *: ** ::* : * . :. ", "identical_positions": 67, "similar_positions": 92, "identity": "15.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110603-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JLS3-1", "uniprot_id": "TAOK2_RAT", "id": "Q9JLS3-1", "name": "Serine/threonine-protein kinase TAO2", "aln": "MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPALQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDAVRELDNLQYRKMKKILFQEAPNGPGAEAPEEE------EEAEPYMHRAGTLTSLESSHSVPSMSISASS-QSSSVNSLADASDNEEEEEEEEEEEEEEEEEGPESREMAMMQE--------GEH-------TVTSHSS----------IIHRLPG----------------------------------------------------SDNLYDDPYQPEMTPGPLQPPAAPPTSTSSSSARRRAYC-----RNRDHFATIRTASLVSRQIQEHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSGRLQRELEAQRAGFGTEAEKLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQLKEELQENPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLARHSLDQDLLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTELGNQLEYNKRREQELRQKHAAQVRQQPKSLKVRAGQLP--MGLPATGALGPLSTGTLSEEQPCSSGQEAILGQRMLGEEEEAVPERM----ILGKEGTTLEPEEQRILGEEMGTFSSSPQKHRSLVNEEDWDISKEMKESRVPSLASQERNIIGQEEAGAWNLWEKEHGNLVDMEFKLGWVQGPVLTPVPEEEEEEEEEGGAPIGTPRDPGDGCPSPDIPPEPPPSHLRQYPASQLPGFLSHGLLTGLSFAVGSSSGLLPLLLL--LLLPLLAAQGGGGLQAALLALEVGLVGLGASYLFLCTALHLPPSLFLLLAQGTALGAVLSLSWRRGLMGVPLGLGAAWLLAWPSLALPLAAMAAGG-KWVRQQGPQMRRGISRLWLRVLLRLSPMVFRALQG-CAAVGDRGLFALYPKTNK--NGFRSRLPVPWP--RQGNPRTTQHPLALLARVWALCKGWNWR------------LARASHRLASCLPPWAVHILASWGLLKGERPSRIPRLLPRSQRRLG--LSASRQLPPGTVAGRRSQTR-------------------RALPPWR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZQ29-1", "uniprot_id": "TAOK2_MOUSE", "id": "Q6ZQ29-1", "name": "Serine/threonine-protein kinase TAO2", "aln": "MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPALQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDAVRELDNLQYRKMKKILFQEAPNGPGAEAPEEEELTPCSQEAEPYTHRAGTLTSLESSHSVPSMSISASS-QSSSVNSLADASDNEEEEEEEEEEEEEEEEEGPESREMAMMQE--------GEH-------TVTSHSS----------IIHRLPG----------------------------------------------------SDNLYDDPYQPEMTPGPLQPPAAPPTSTSSS-ARRRAYC-----RNRDHFATIRTASLVSRQIQEHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSGRLQRELEAQRAGFGTEAEKLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQLKEELQENPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLARHSLDQDLLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTELGNQLEYNKRREQELRQKHAAQVRQQPKSLKVRAGQLP--MGLPATGALGPLSTGTPSEEQPCSSGQEAILDQRMLGEEEEAVPERR----ILGKEGTTLEPEEQRILGEEMGTFSSSPQKHRSLANEEDWDISEEMKEIRVPSLASQERNIIGQEEAAAWSLWEKEGGNLVDVEFKLGWVQGPVLTPVPEEEEEEEEEGGAPIGTHRDPGDGCPSPDIPPEPPPSHLRQYPTSQLPGLLSHGLLAGLSFAVGSSSGLLPLLLL--LLLPLLAAQGGGGLQAALLALEVGLVGLGASYLFLCTALHLPPGLFLLLAQGTALLAVLSLSWRRGLMGVPLGLGAAWLLAWPSLALPLAAMAAGG-KWVRQQGPQMRRGISRLWLRILLRLSPMVFRALQG-CGAVGDRGLFALYPKTNK--NGFRSRLPVPWP--RQGNPRTTQHPLAQLTRVWAVCKGWNWR------------LARASHRLASCLPPWAVHILASWGLLKGERPSRIPRLLPRSQRRLG--LSASRQLPPGTVAGRRSQTR-------------------RTLPPWR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UL54-1", "uniprot_id": "TAOK2_HUMAN", "id": "Q9UL54-1", "name": "Serine/threonine-protein kinase TAO2", "aln": "MPAGGRAGSLKDPDVAELFFKDDPEKLFSDLREIGHGSFGAVYFARDVRNSEVVAIKKMSYSGKQSNEKWQDIIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAVTHGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSGHWSEYFRNFVDSCLQKIPQDRPTSEVLLKHRFVLRERPPTVIMDLIQRTKDAVRELDNLQYRKMKKILFQEAPNGPGAEAPEEE------EEAEPYMHRAGTLTSLESSHSVPSMSISASS-QSSSVNSLADASDNEEEEEEEEEEEEEEE--GPEAREMAMMQE--------GEH-------TVTSHSS----------IIHRLPG----------------------------------------------------SDNLYDDPYQPEITPSPLQPPAAPAPTSTTSSARRRAYC-----RNRDHFATIRTASLVSRQIQEHEQDSALREQLSGYKRMRRQHQKQLLALESRLRGEREEHSARLQRELEAQRAGFGAEAEKLARRHQAIGEKEARAAQAEERKFQQHILGQQKKELAALLEAQKRTYKLRKEQLKEELQENPSTPKREKAEWLLRQKEQLQQCQAEEEAGLLRRQRQYFELQCRQYKRKMLLARHSLDQDLLREDLNKKQTQKDLECALLLRQHEATRELELRQLQAVQRTRAELTRLQHQTELGNQLEYNKRREQELRQKHAAQVRQQPKSLKVRAGQRPPGLPLPIPGALGPPNTGTPIEQQPCSPGQEAVLDQRMLGEEEEAVGERR----ILGKEGATLEPKQQRILGEESGAPSPSPQKHGSLVDEEVWGLPEEIEELRVPSLVPQERSIVGQEEAGTWSLWGKEDESLLDEEFELGWVQGPALTPVPEEEEEEEE--GAPIGTPRDPGDGCPSPDIPPEPPPTHLRPCPASQLPGLLSHGLLAGLSFAVGSSSGLLPLLLL--LLLPLLAAQGGGGLQAALLALEVGLVGLGASYLLLCTALHLPSSLFLLLAQGTALGAVLGLSWRRGLMGVPLGLGAAWLLAWPGLALPLVAMAAGG-RWVRQQGPRVRRGISRLWLRVLLRLSPMAFRALQG-CGAVGDRGLFALYPKTNK--DGFRSRLPVPGP--RRRNPRTTQHPLALLARVWVLCKGWNWR------------LARASQGLASHLPPWAIHTLASWGLLRGERPTRIPRLLPRSQRQLG--PPASRQPLPGTLAGRRSRTRQS-----------------RALPPWR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AY27-1", "uniprot_id": "A0A8M3AY27_DANRE", "id": "A0A8M3AY27-1", "name": "non-specific serine/threonine protein kinase", "aln": "MPSSVRAGSLKDPEVAELFYKEDPEKLFTDLREIGHGSFGAVYFAHDIRTNEVVAIKKMSYSGKQSNEKWQDIIKEVKFLQKLRHPNTVEYRGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEVEIAAITHGALQGLVYLHSHNMIHRDVKAGNILLTEPGQVKLGDFGSASIVAPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPLFNMNAMSALYHIAQNESPVLQSNHWSDYFRNFVDSCLQKISQDRPTSDVLLKHHFLCRERPVTVVMDLIARTKDAVRELDNLQYRKMKKILFQETHNGPATEGTEEEE-SCVFQDVEQYMLRTGTVNSMESSHSLPSMSISASS-QSSSVNSLADGSD--------------------DSGEMAMMQE--------GEH-------TVTSNSS----------VLHKALN----------------------------------------------------HDNIYDDPYQPEMDSQQQQQQGP-------SGGRRR--------RGRDHFATIRTASLVTRQIQEHEQGSALREQMSGYKRMRRQHQKQLMALENKLKAEMDEHQLRLDKELETQRNNFGSEADKLSKKHQAILEKETKGAIAEEKKFQQHILGQQKKELTSLLESQKRHYRQRKEQLKEELNENQSTPKREKQEWLVQQKECLQQVQAEEEAGLLRRQRQYYELQGRQYKRKMLLSRHNLEQDLLREDLNKKQTLKDLECAMLLRHHESTQELEFRQLALVQRTRADLIRTQHQTELTNQMEYNKRREQELRQKHAVEVRQQPKSLRVSDSDIT---ENSTEGAGLDIEGVEPQDEEKRDGEKIDGDEMQPLGAVEETSEQEMREVNVLEENDTEETLTDQCDVIDSEGKVEELAESADNVNESADKSPKIADEEQVEDKIDNDLRQVEGLQWDGESESDSEEEDRGVADGCPSELIPGPSFERRPLERDLDELSEFYFPDTLEELEP--PPVYIPPSPSSSSQ-----PSLPSLFSHAICLVLSLSAAVQPSVLTLLLLSIFLLSLRRSPPLPSLASILLSGELAFLALFFSYLFLRSCCSLSFSTYLLLTYWGSGLFSLALSLSLGLYYVPIALISASFLSSPSLFLTLYLIVVLVVRPARVFLQNTPRKLNRLWMRVLFRLPKPLFTVCQSVLGGLTERSLYDMFPKAGRNWGGRQSRIPVPLKSLHTAQYQAKSKHSLLFARILLMGRRFVRRPLGTLTDLANSMVLHIAKRVLKELPQNYLKRLQEFGLLRKEKTSKLPVLLPRMVREHRRRMRERRETERRRRVERERMYREEGRWESVLRRTASGRSLKGKMVPWR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q0KHQ5-1", "uniprot_id": "TAO_DROME", "id": "Q0KHQ5-1", "name": "Serine/threonine-protein kinase Tao", "aln": "MPS-ARPGSLKDPEIADLFNKHDPEKIFEDLREIGHGSFGAVYYARCNLTREIVAIKKMSYTGKQSQEKWQDILKEIRFLRQLNHPNTIEYKGCYLRESTAWLVMEYCVGSASDIIEVHKKPLHEDEIAAICLGVLSGLSYLHSLGRIHRDIKAGNILLTDNGVVKLADFGSAAIKCPANSFVGTPYWMAPEVILAMDEGQYDGKVDVWSLGITCIELAERKPPYFNMNAMSALYHIAQNESPTLPKNDWSDAFCSFVELCLKKMPAERPSSAKLLTHAYVTRPRSDTVLLELIARTKSAVRELDNLNYRKMKKILMVDTCETESAVGDTDD------QQDDHAGGDSSKSNSITSEHSIHSVGVSAASSQSSSSNSIPAAAQNHHHIAAHHHQQAASAAVAAAMHHHHHPHQQPPPSWPSGQQGQPVPPGAVSRNSSRHRNRPPLPNIMHSMNNNVTPTNSASVVPAPAPAPVLPPPISVLPHLSAMGHVGGGGTGTGGSGGGSPASGGPLADRIQPVQPRYLTTPAAQAAVYAASSASSQQAISNAVNDHGPNNFATIRTTSIVTKQQKEHMQ-EEMHEQMSGYKRMRREHQAHLVKLEEKCKVDMEAHKTALDKEYDTLLHNFTRDLDRLETKHQQDVERRAKQTSAAEKKLHKEITLKQENDRKVYDLNRKKEYKANKERWKRELSMDESTPKRQRDLTLQSQKDNLKQHEAQEEQRMLQAQKQYIELEMRKFKRKRMIMQHEHEDQQLRDELGKKEQQLQQAHAMLLKHHEKTQELEYRQQKSVHQLREEQINKQHDTELHNQKDYMDRIKKELVRKHAVELRQQPKSLKQKELQIR-----------KQFRETCKTQTKQYKRYKAQVLQTTPKEQQKEVIKQLK------EEKHRKLTLLG--------------EQYEQSIADMFQSQSYKLDESQVIECQRTHEQLEYELEMLTAYQNKNKKQAQ--------------------EQRDRERRELENRVSVRR-----------------------------GLLENKMDAELQQFNQERAERLRMKHE--------------KHTKELEAFDNESIALGFSTLSLIEVSREAYAD----EEGSLSGSMISLAHSNSSTSFPAGSL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: *.******::*:** *.****:* **************:*: . *:********:****:******:**::**::*.****::*:****** *********:*****::*******:* ****: *.*.** **** . ****:*******:: * ***.*****:* .*********************************************** ******************.* ...**: * .**: **:*:. :**:* **.* :: * *. **:::** ***.********:********: :: : .: . :: :: : :.. .*: *.**: *:.:**:* **** **:. .:: . :: *:: :*: :** ::* . .. * ** . * . :: :. ::******:*:*::* :** * . ::**:********:** :*: **.: : : : *. *::* :: .* : ::* :** *:.:: : * *:*:::.* :*::: :*: *: .**: *.**. : *****:: * **: *:* :*:** :*: *:** **: *::*** :: :*. ::: **::*.**: : *:**::** *:*** ** *:: * : . **:*** ** :* .* ::** :***.::*******: : : : . : :*. : :: : .: : :. . : : . :: :.: :. .. . .::.: : *. . * : * : : :.* * * * . . :.*: . .* . ", "identical_positions": 371, "similar_positions": 248, "identity": "27.06%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110603-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P56270-1", "uniprot_id": "MAZ_HUMAN", "id": "P56270-1", "name": "Myc-associated zinc finger protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFPVFPCTLLAPPFPVLGLDSRGVGGLMNSFPPPQGHAQNPLQVGAELQSRFFASQGCAQSPFQAAPAPPPTPQAPAAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVAAAPPAPAAASTVDTAALKQPPAPPPPPPPVSAPAAEAAPPASAATIAAAAATAVVAPTSTVAVAPVASALEKKTKSKGPYICALCAKEFKNGYNLRRHEAIHTGAKAGRVPSGAMKMPTMVPLSLLSVPQLSGAGGGGGEAGAGGGAAAVAAGGVVTTTASGKRIRKNHACEMCGKAFRDVYHLNRHKLSHSDEKPYQCPVCQQRFKRKDRMSYHVRSHDGAVHKPYNCSHCGKSFSRPDHLNSHVRQVHSTERPFKCEKCEAAFATKDRLRAHTVRHEEKVPCHVCG-KMLSSAYISDHMKVHSQGPHHVCELCNKGTGEVCPMAAAAAAAAAAAAAAVA----------------------APPTAVGSLS---GAEGVP---------VSSQPLP----------------------------------SQPW-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P56671-1", "uniprot_id": "MAZ_MOUSE", "id": "P56671-1", "name": "Myc-associated zinc finger protein", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFPVFPCTLLAPPFPVLGLDSRGVGGLMNSFPPPQGHAQNPLQVGAELQSRFFASQGCAQSPFQAAPAPPPTPQAPAAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVVTAPPAPAAASTVDTAALKQPPAPPPPPPAVSAPAAEAAPPAAAATIAAAAATAVVAPTSTVAVAPVASVLEKKTKSKGPYICALCAKEFKNGYNLRRHEAIHTGAKAGRVPSGAMKMPTMVPLSLLSVPQLSGASGGGGEAGAGGGTTAVAAGGVVTTTASGKRIRKNHACEMCGKAFRDVYHLNRHKLSHSDEKPYQCPVCQQRFKRKDRMSYHVRSHDGAVHKPYNCSHCGKSFSRPDHLNSHVRQVHSTERPFKCEKCEAAFATKDRLRAHTVRHEEKVPCHVCG-KMLSSAYISDHMKVHSQGPHHVCELCNKGTGEVCPMAAAAAAAAAAAAAVVA----------------------APPTAVGSLS---GAEGVP---------VSSQPLP----------------------------------SQPW-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5YBK6-1", "uniprot_id": "A0A8I5YBK6_RAT", "id": "A0A8I5YBK6-1", "name": "Myc-associated zinc finger protein", "aln": "MDPSNWSSFIFQVTTPAPPPLPPLPHPLLPALPPVPHPLRAPGARAAVPLPPSRPPPPSPRRRLGARARRGPKLLPRSPHPAPPGSNCRHHRRRRPGPRPRPRPSAPRGLSPPPRGRRLRRRAPRPTRRPPSLPPAGRGARAAGRPSGHAFGSAQPGRPGAAPRARAPRGPCPRLPLSTGGPTVAEAMFPVFPCTLLAPPFPVLGLDSRGVGGLMNSFPPPQGHAQNPLQVGAELQSRFFASQGCAQSPFQAAPAPPPTPQAPAAEPLQVDLLPVLAAAQESAAAAAAAAAAAAAVVTAPPAPAAASTVDTAALKQPPAPPPPPPAVSAPAAEAAPPAAAATIAAAAATAVVAPTSTVAVAPVASVLEKKTKSKGPYICALCAKEFKNGYNLRRHEAIHTGAKAGRVPSGAMKMPTMVPLSLLSVPQLSGASGGGGEAGAGGGTAAVAAGGVVTTTASGKRIRKNHACEMCGKAFRDVYHLNRHKLSHSDEKPYQCPVCQQRFKRKDRMSYHVRSHDGAVHKPYNCSHCGKSFSRPDHLNSHVRQVHSTERPFKCEKCEAAFATKDRLRAHTVRHEEKVPCHVCG-KMLSSAYISDHMKVHSQGPHHVCELCNKGFTTAAYLRIHAVKDHGLQAPRADRIL----------CKLCSVHCKTPAQLAGHMQTHLGGAAPP---------IPGDAPQ----------------------------------PQPTC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M1QH64-1", "uniprot_id": "A0A8M1QH64_DANRE", "id": "A0A8M1QH64-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAAWSNFLFQTTP-------SHTQVEGTLQS-------------ELLPVHTTSPQAPPTD------------------------------HMAPPP----STVDTAALNEDPVPVKP----------VSRPARAAHICSICSKQFKNSYNLRRHQSVHTGIRMKTGAQNQEAQAKDSSEKHTVLLSLLHLQQQSQTLPPPTVMPAQHTQILAPPDGNDVAMESVASTVTALPPPPPVVMATGEPVQRPVNQNPNPVRKNHACETCGKAFRDVYHLNRHRLSHSDEKPFSCPICQQRFKRKDRMSHHVRSHQGGVEKPYVCPHCAKAFSRPDHLNSHVRQVHSSERPFKCPTCESSFATRDRLRAHMIRHEEKVPCHICG-KLLSAAYITDHMRVHNQSQHHSCHLCNRSFTTLTYLRVHAQKHHGQEWKESGGGFGSTGSGGILVCQLCGVHCKTPTQLQGHMGTHNPPASDPSPIITTTTTTTSEAMPGSTVTLCNMVSAPTVFVSGNTVVDLLVTDCSSIIPQPQS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JQX6-1", "uniprot_id": "A8JQX6_DROME", "id": "A8JQX6-1", "name": "Transcription factor Ouib", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKEFCRTCGKTVVADECLQIFTPAGRKLLQCVRSITNCWLQNVQDLPNHICTDCQVLLSQVQKFRR-----------------------RCAKIEKYFARRRRRMNLGEAPA--------------AMEQLRVQQAAAPDPLGIDELMSASDIKIEPIQLQMEEDPQAPYPENQLEQALSYGNAPGEDILPLPEDYGEAQTEVATTTNEPAQRRSKNTAKIKSKKHTMRVGRKLIHVKVIDDKQPKRIVDRNGPSAKPCICEHCGRQFKDTSNLHVHLLRHTGTKPFECDQCHQKCYTLHLLRRHQLKHT---EGPYACTFCGLEYSTN---SSRVRHEREACKKGRAPQSKWEIIKKG---------ERTFHCEVCDLWFLRAGNFTQHINSSSHIENERRKKRKSNPTAINS-----------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * . : * : . * * : *. . . .: . . . :. : .: . . . * . ... . . . * ** **: *:*. :*: * * *:. **:.* *:*: . : * .* . ** *..*. :* .*:**: :.: : :. .: : .:. *... *.:*. :* :. :::*:. .: :. . : . ", "identical_positions": 37, "similar_positions": 85, "identity": "5.04%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110606-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D995-1", "uniprot_id": "CNTD1_MOUSE", "id": "Q9D995-1", "name": "Cyclin N-terminal domain-containing protein 1", "aln": "MNMEGPLRPRLVNCSDFQFGVVTTETIENALLHLAQQNEQAVKEAAGRTGSFRETRIVEFVFLLSEQWCLEKSVSYQAVEILERFMLKQAEDICRQATLQLRGKDTELQSWRAMKEQLVNKFILRLVSCVQLASKLSFHYKIVSNITVLNFLQALGYVHTKEELLESELDILKSLNFQINLPTPLAYVEMLLEVLGYNGCLVPATQLHATCLTLLDLVYLLHEPIYESLLRASIENSTPSQLQGEKFLSVKEDFMLLAVGIIAASAFIQNHECWSQVIGHLQSITGIASESIAEFSYAILTHSVGANTPGPQQPVP-HKAARALRTAAAAASSNT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N815-1", "uniprot_id": "CNTD1_HUMAN", "id": "Q8N815-1", "name": "Cyclin N-terminal domain-containing protein 1", "aln": "--MDGPMRPRSASLVDFQFGVVATETIEDALLHLAQQNEQAVREASGRLGRFREPQIVEFVFLLSEQWCLEKSVSYQAVEILERFMVKQAENICRQATIQPRDNKRESQNWRALKQQLVNKFTLRLVSCVQLASKLSFRNKIISNITVLNFLQALGYLHTKEELLESELDVLKSLNFRINLPTPLAYVETLLEVLGYNGCLVPAMRLHATCLTLLDLVYLLHEPIYESLLRASIENSTPSQLQGEKFTSVKEDFMLLAVGIIAASAFIQNHECWSQVVGHLQSITGIALASIAEFSYAILTHGVGANTPGRQQSIPPHLAARALKT---VASSNT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TYB3-1", "uniprot_id": "A0AB32TYB3_DANRE", "id": "A0AB32TYB3-1", "name": "", "aln": "MAKNTMFSFPTRDQRNLSFGEVSLDILTDILSNLNNKNKSNLEKVSNMCGCLKERRIVECVFLLCEELGLSPVVAYQAIEILERFTAKHIEDLIRSRNYSSDTEDTR-NCADLIFQTLKHKFFLFIISSIQIASKLDLYTNVVNNDIAMRFLQALSYPSSKKQLLDSEIFILKTLNFNLNVPNPVTYVETLLEVLGHNDASVPVAQLHDQCVPVLQFIYLQRETIYNSLLIAAIGCPSPSHEQRAKFVSVTEDFMLLGVGVIAVAAFIHHISTCEKVVEELTEITGISAQSIMDFAHVTLMH-ITDNTSK-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . ::.** *: : : : * :* ::*:. :.:.:. * ::* :*** ****.*: *. *:***:****** *: *:: *. . . :. . : : : * :** * ::*.:*:****.: :::.* .:.*****.* :*::**:**: :**:***.:*:*.*::*** ******:*.. **. :** *:.:*:::** :*.**:*** *:* .:**: * ** **.******.**:**.:***:: . .:*: .* .****: ** :*::. * * : **. ", "identical_positions": 119, "similar_positions": 108, "identity": "35.52%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110606-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96J92-1", "uniprot_id": "WNK4_HUMAN", "id": "Q96J92-1", "name": "Serine/threonine-protein kinase WNK4", "aln": "--------------MLASPATETTVLMSQTEADLALRPPPPLGTAGQPRLGP--PPRRARRFSGKAEPRPRSS------------RLSRRSSVDLGLLSSWSLPASPAPDPPDPPDSAGPGPARSPPPSSKEP----------PEGTWTEGAPVKAAEDSARPELPDSAVGPGSREPLRVPEAVALERRREQEEKED-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METQAVATSPDGRYLKFDIEIGRGSFKTVYRGLDTDTTVEVAWCELQTRKLSRAERQRFSEEVEMLKGLQHPNIVRFYDSWKSVLRGQVCIVLVTELMTSGTLKTYLRRFREMKPRVLQRWSRQILRGLHFLHSRVPPILHRDLKCDNVFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDEAVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGRKPNSFHKVKIPEVKEIIEGCIRTDKNERFTIQDLLAHAFFREERGVHVELAEEDDGEKPG----LKLWLRMEDARR-GGRPRDNQAIEFLFQLGRDAAEEVAQEMVALGLVCEADYQPVARAVRERVAAIQRKREKLRKAR----------------------------------------------------------------------ELEALPP--------EPGPPPATVP--------------------------------------------------------------------------------------MAPGPPS----------------VFPPEPEEPEADQHQP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FLFRHASYSSTTSDCETDGYLSSSGFLDASDPALQPPGGVPS---------------SLAES------------------------------------------------------------------------------------HLCLPSAFALSIPRS-GPGSDFS-PGDSYASDAASGLSDVGEGM----------------------GQMRRPPGRNLRRRPRSRLRVTSVSDQNDRVVECQLQTHNSKMVTFRFDLDGDSPEEIAAAMVYNEFILPSERDGFLRRIREIIQRVETLLKRDTGPM---------------------------------------------------EAAEDTLSPQEEPAPLPALPVPLPDPSNEELQSSTSLEHRSWTAFSTSSSSPGTPLSPGNPFSPGTP-ISPGPIFPITSPPCHPSPSPFSPISSQVSSNPS---PHPTSSPLPFSSSTPEFPVPLSQCPWSSLPTTSPPTFSPTCSQVTLSSPFFPPCPSTSSFP-------------STTAAPLLSLAS-------------------AFSLAVMTVAQSLLSPS------PGLLS-------------------------QSPPAPPSPLPSLPLPPPVAPGGQESPSPHTAEVESEAS----------------------------------------PPPARPLPGEARLAPISEEGKPQ------------------------------------------------------LVGRFQVTSSKEP------AEPLPLQPTSPTLSGS--------------------PKPSTPQLTSESSDTEDS--AGGGPETREALAESDRAAEG-------LGAGVEEEGDDGKEPQ----------------------------VGGSPQPLSHPSPVWMNYSYSSLCLSSEESESSGEDEEFWAELQSLRQKHLSEVETLQTLQKKEIEDLYSRLGKQPPPGIVAPAAMLSSRQRRLSKG-----SFPTSRRNSLQRSE-PPGPGIMRRNSLSG-SSTGSQE-QRASKGVTFAGDVGRM---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80UE6-1", "uniprot_id": "WNK4_MOUSE", "id": "Q80UE6-1", "name": "Serine/threonine-protein kinase WNK4", "aln": "--------------MLAPRNTETGVPMSQTEADLALRPSPALTSTGPTRLGP--PPRRVRRFSGKAEPRPRSS------------RPSRRSSVDLGLLSSWSQPASLLPEPPDPPDSAG--PTRSPPSSSKEP----------PEGTWMGAAPVKAVD-SACPELTGSSGGPGSREPPRVPDAAARERRREQEEKED-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TETQAVATSPDGRYLKFDIEIGRGSFKTVYRGLDTDTTVEVAWCELQTRKLSRAERQRFSEEVEMLKGLQHPNIVRFYDSWKSVLRGQVCIVLVTELMTSGTLKTYLRRFREMKPRVLQRWSRQILRGLHFLHSRVPPILHRDLKCDNVFITGPSGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDEAVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTSGTKPNSFYKVKMPEVKEIIEGCIRTDKNERFTIQDLLAHAFFREERGVHVELAEEDDGEKPG----LKLWLRMEDARR-GGRPRDNQAIEFLFQLGRDAAEEVAQEMVALGLVCEADYQPVARAVRERVAAIQRKREKLRKAR----------------------------------------------------------------------ELEVLPP--------DSGPPPATVS--------------------------------------------------------------------------------------LAPGPPS----------------AFPPEPEEPEADQHQS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FLFRHASYSSTTSDCETDGYLSSSGFLDASDPALQPPGGLPS---------------SPAES------------------------------------------------------------------------------------HLCLPSGFALSIPRS-GPGSDFS-PGDSYASDAASGLSDMGEG-----------------------GQMRKNPVKTLRRRPRSRLRVTSVSDQSDRVVECQLQTHNSKMVTFRFDLDGDSPEEIAAAMVYNEFILPSERDGFLSRIREIIQRVETLLKRDAGPP---------------------------------------------------EAAEDALSPQEEPAALPALPG----PPNAEPQRSISPEQRSWAAFSTSPSSPGTPLSPGAPFSPGTPPVFPCPIFPITSPSCYPCP------FSQVSSNPY---PQAPSSLLPLSSSASQVPLPS-----SSLPISAPLPFSPSYPQDPLSPTSLPVCPSPPSLP-------------STTAAPLLSLAS-------------------AFSLAVMTVAQSLLSPS------PGLLS-------------------------QSPPAPPGPLPSLPLS--LASCDQESLSAQTAETENEAS----------------------------------------RNPAQPLLGDARLAPISEEGKPQ------------------------------------------------------LVGRFQVTSSKEP------AEP-PLQPASPTLSRS--------------------LKLPSPPLTSESSDTEDS--AAGGPETREALAESDRAAEG-------LGVAVDDEKDEGKEPL----------------------------LGGSSPILSHPSPVWMNYSYSSLCLSSEESESSGEDEEFWAELQNLRQKHLSEVEALQTLQKKEIEDLYSRLGKQPPPGIVAPAAMLSCRQRRLSKG-----SFPTSRRNSLQRSD-LPGPGIMRRNSLSG-SSTGSQE-QRASKGVTFAGDIGRM---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PWP2-1", "uniprot_id": "A0A8M9PWP2_DANRE", "id": "A0A8M9PWP2-1", "name": "non-specific serine/threonine protein kinase", "aln": "--------------------------MSHAEVEFAARAFPALPVELEDDCLSRVPMLRTHSLSARRNSYVLHK------------LDPQIYNETLSKGLSWSAENILLSADSKTDPSPPMSPSPVSSPESVTP----------NADSAASEDWRSPVQQPRSPQDASSDSDNEGTKGENAVRRRQFLSRLEQDEKED-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IETKAVATSPDGRYLKFNIEIGRGSFKTVYKGLDTETTVEVAWCELQTRKLSKVERQRFSEEVEMLKGLQHPNIVRFYDSWKSNVKGQKCILLVTELMTSGTLKTYLKRFKEMKLKLLQRWSRQILKGLHFLHTRSPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDEAVDVYAFGMCILEMTTSEYPYSECQNAAQIYRKVTSGIKPDSFHKVKVPELKEIIEGCIRMNKDERYTIQDLLEHTFFQEHNGVHVELAEEDDMIKSG----LKLWLRMDDTKKLHGKYKDNNAIEFLFELYKDVPEEVAQEMVVLGFVCEADYKLVAKAMRDRVTAIKRQREKHRRLAEEQQKKK---------------------------------------------------------EGIIEEEPELLSPRSTVQMSETPTPSPVQIP--------------------------------------------------------------------------------------STPLFPEPVRSPATGSSDFGINGGFPPEPEEPEADQH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FHIRQTSCSSATSDCETDGYLSPSGSQDCTEASTGNVSYSPTRLSQPATPIDAPPIISPPIP------------------------------------------------------------------------------------ALRFPSSIAVSAKTERGPLSPFSSPVDSYASDVTSGLSDGYEGQS----------------EQGSKAAARRTAGKLFRRRTRSRLRITGLSDKVDRVVECQLQTHNDKMVTFKFDLDGDNPEDIAAVMVHNEFILPSEKEGFIYRIADIIKRAESMMKKESLGH---------------------------------------------------HESHGGSRPSYINNVNSLSAS----QPNLHSLARAHSSSSLPAELGLGSGARASPLGAAGDVTSSTRPLLRSQSFHNAPGSHHPHHILPSSVYPPDPRMPHSNLPHMQQYIPSYIPAGTHFPFPYPPHPGSPKPAHTPLSRVHSSPAYTLSSTPVSPSPLSSDIPPDINMMSPAPGMWPPHTQPLFSLAN-------------------VLSMA-MSMAHSFMPPQNLAQTMPGFQPGYPAMFAPQYPPSQEYYQTVDSQFRDSPMSPPSRASSAPATGVSRSVQQEASAREGAMFAKETCQ---------------------------------DNPPDFRSASSRLLLEHRSSPGSSSGRSSSPRASPDSRVSSSSPRSLSPLAALETTRATQSRENSLPSGSQCKEAFTEPKSTVTVGRFQVTPSKEIPAPSRCSESENTQAQTPSVLHSD-----------------NPIRPLDQPFSAQNPPQCDLSISAEPPEARSNQGNQDRDRQE-------VNDDDDYDEGEDKKQRRKKKGRRVDCGPGLMGTSVDSGFSVWDGHAGSPPYATPLHNLWMSYTRSSSYMSSDESES--EDEEMWEELQQLREKHLCEVQSLQTVQKREIEELYAKMGKVPPPCIVSPAAMLSSRQRRLSKGG----NFPSSRRNSLQRLDILPLTGIMRKNSLSGDSSSSSQEGSRHTKGVTFAADFTRM---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PGC5-1", "uniprot_id": "WNK_DROME", "id": "M9PGC5-1", "name": "Serine/threonine-protein kinase Wnk", "aln": "MGQTLCDFVRQQEVVPANRARKGSAISEDGTTSCTTQPQRNTSISSEEQTVQGANIQKSGHRSFNRSASSRQKPNPTSKLKDTLNRKPTCKQGTLSAHTSTSSTTSIQSSPIEPASSLPTLNTTPTPPAASKSNLFVRVLRRFSNNTLPGKTASSPKNVDDVPKVNDNNNGDLGKQQSTDVEVLCSQDNQSREQNEDEMDSKIEPADAISNQKAGLTSGKPKKDKSVKGTSQAVVSDTKKMEARKSSSDTVIEPLIKQQAPLHSSKTTPTTLTANFVQNIRFVRKNVEQSGRNTNPLQFVELETEFPRDYDDNIEMLSREAEHLEEQFRTPTRSNATDATSHHVAGIIDNIITEASRSLTIEKTEDDVPLKSSTKHSSGVKRVGFQVEDKDDTEVQSEKQAKSFDDITKKAESSEASAEEAAVTGSSTDASASPLPSTSLVSTTSSATSITKSKSDEDDDPVAMSPCGRFFKYDKEVGRGSFKTVYRGLDTLTGVPVAWCELLDKQVKKSERTRFREEADMLKKLQHPNIVRFYTYWEFPIGRKKNIVLVTELMLSGTLKSYLKRFKKIHPKVLKSWCRQILKGLNFLHTRQFPIIHRDLKCDNIFITGTTGSVKIGDLGLATLKNRSHAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMAISEYPYSECKGPAQIYKKVISGIKPAALAKVEDPNVRDIIERCIELKKEDRPSCNELLESEFFDEDIGIRVEPTASEQFLSDPSISIIEFRLRFMDPKKRSSRHKENEAIQFEYNIRHDEYEQIAQEMMKENIISEDDSRAVARLLKVQVVSLLKERAQRQTQIKLQNEKSRLEKLALQKQRESLPTNVDEDEEEEEESEDEEDGVKWNQRLQLRYDLLNTDSETSLALSTNSVEPQQLSTRSNTSIPNSGIQQPVQVPGQVPVSQLISVQPQAIPSPAIPMQQKPTVHYIQPPQLASYQNSNASMQEMTNNQVISPTGSQQMQQQQPVVAPTVNHQVMPQQQVNQQQQQPQMMQQIPQQVQVQQPQTVLPPQPHEQQPQQQQQPLQQQLQQLMHTNVQAPDLTQQQQMAQQQAQQYFQQQQQQPQQAVNMQQAYAMQQAGQQQQLSQPLQIQQQILQQQQVAVSHQQQIMQQQLAQHQLQQLQQQQLQQQQLQQQQQIQQQQLQQQQLQQQQFVQQYAQAMPQQQHQQLVTGSQVMAPHQHQQPIQIPVQMQVPPTSVAPPIQHTYNQQGGQVTLSDAQQQQHPGFSAVPQQAAPFIQQPTQQPIQLSMPLEQQLQQLLHSQPAQQQQAMSQQQQQPLVQQQQLPLVQQQPPLVQQQQPLVQHQQPSVQHQQPLVQQPQQQQPQPQNQQPQPQTQQTHVVQQQPPQQQPAVEQISQISSQVPVQQENLQPIQVNKDANVATDAMSLNSAHGALEPAPKTEPQNSADAEKQQKQTGTGTRSQKPRRSNRSGNERIPKLSVTSVDEGSVINCHMENKLKTITFKFDIGDVNPVEIANKLIAQDLLSNCQSTVFVEMINEIVDQVKQNPNQIPIPTNYRRNIEKVRHASLTRQRSTFRSHQRHRSRDETASDITKMFEPTIHGVETLPSGGGGAEQSNCNLTLEARSHLSNIPNAKEPQLNVSTPPTTTSTMSSSSTASRDAPNSSNDVTIGSGSVSRKTSTASEYTSLSIDYMPDSNITPTGPEPPLDDGKDKKPCSLAIARMQKLLESAGNGAPRSLNLPLNRHLKIQEDLKHTRSLDDLTAVKITFDMPNKAALDTSENAQQATEAEAEKPKDKSGQAVGNQGTGAANTLEQLKIELENITHAHAFASAVVASINNRAPHQASPAMSSLKATSGQPQTQEITKPNNGAGPSVPSVGQNTPTAALTSARGSGSSVYNSRRTSIDNSVGSDMHLHTATNLEGTVSNPDPIPTEASVGITIATGHEKQLSKQPSLEKPSATSILTNNSDPPQRNPSNGSINQNSIADLEKKLAALRNTENTEESATATLSVVPKQVEEVVNPSARKISRFSVSRVQEQKTSTGVEEPAQGQLKIDLQVAGPGGQVQTNNSVQNGSVVNTPTEVISSPIQNVPLAINGIQLMYQQPQQIHQLPGGTSTTTSGAGTQCIVVPQVVNQNGTHVQQPSNLQPQQQSVHPNMTQQPQQTPLNGHPSMVNTLQQQPPQQSLPMQTIQSQQQQHNQMPIISQQQQQQILMQQQQQQGSQQGSQQFNLPGTQQTHPQHQFIQSQPNQLHSLPPQVVSMAQGNLPHQLPPMQTMGAQQQMISQQQHQLQMQSHMHQQNVPG--MYNQQTGARVAAPQNFAGAVPNHLLQQSPLMASQQPAQPMQHVMQPIFNATSGEVTEEPVSLAATHPHLLPSDIQSDIKHNLDSLVNQLCNTRLGTNQHQRLLLLRQRQLIEEDELRLKHYVEYEKFQKALRQSISTNVPANAAYYSAAAAQLPTNLAAPAAPSSSNPTSTSSANT", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P0C0A1-1", "uniprot_id": "VPS25_RAT", "id": "P0C0A1-1", "name": "Vacuolar protein-sorting-associated protein 25", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAMS-----FEWPWQYRFPPFFTLQPNVDTRQKQLAAWCSLVLSFCRLHKQS----SMTVMEAQESP----LFN--NVKLQRKLPVESIQIVLEELRKKGNLEWLDKNKSSFLIMWRR---------------------------------PEEWGKLIYQWVSRSGQNNSVFTLYELTSGEDTEE--------------------------------------------EEFHGLDEATLLRALQALQQEHKAEIITVSDGRGVKFF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * ::: : .* *: .:** .***.* :: . ::: : * :: : : : : : :: . * *. : : : .* * * . : *.* :.. . :**: *: : * ** : :. . : :: . .* : : .: ** ", "identical_positions": 27, "similar_positions": 57, "identity": "1.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110606-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5Y871-1", "uniprot_id": "A0A8I5Y871_RAT", "id": "A0A8I5Y871-1", "name": "Protein argonaute-1", "aln": "LPNSRRWPDSVLTGFFVFTAAGAYLPPLQQVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLERDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CJG1-1", "uniprot_id": "AGO1_MOUSE", "id": "Q8CJG1-1", "name": "Protein argonaute-1", "aln": "-------MEAGPSG----AAAGAYLPPLQQVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UL18-1", "uniprot_id": "AGO1_HUMAN", "id": "Q9UL18-1", "name": "Protein argonaute-1", "aln": "-------MEAGPSG----AAAGAYLPPLQQVFQAPRRPGIGTVGKPIKLLANYFEVDIPKIDVYHYEVDIKPDKCPRRVNREVVEYMVQHFKPQIFGDRKPVYDGKKNIYTVTALPIGNERVDFEVTIPGEGKDRIFKVSIKWLAIVSWRMLHEALVSGQIPVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKPLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNASYNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKNERIGKSGNIPAGTTVDTNITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHISGQSNGRDPQALAKAVQVHQDTLRTMYFA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WG39-1", "uniprot_id": "X1WG39_DANRE", "id": "X1WG39-1", "name": "Protein argonaute-1", "aln": "-------MEAGPSG---AVPVGPYPPPLQQVFQAPRRPGMGTVGKPIKLLANYFEVEIPKMDVFHYEVDIKPDKCPRRVNREVVEYMVQHFKPQLFGDRKPVYDGKKNIYTVLALPIGSEKVDFEVTIPGEGKDRIFKVSIRWLAKVSWRLLQETLVSGRLQVPLESVQALDVAMRHLASMRYTPVGRSFFSPPEGYYHPLGGGREVWFGFHQSVRPAMWKMMLNIDVSATAFYKAQPVIEFMCEVLDIRNIDEQPKTLTDSQRVRFTKEIKGLKVEVTHCGQMKRKYRVCNVTRRPASHQTFPLQLESGQTVECTVAQYFKQKYNLQLKYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIKATARSAPDRQEEISRLMKNANFNLDPYIQEFGIKVKDDMTEVTGRVLPAPILQYGGRNRAIATPNQGVWDMRGKQFYNGIEIKVWAIACFAPQKQCREEVLKNFTDQLRKISKDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYSGLQLIIVILPGKTPVYAEVKRVGDTLLGMATQCVQVKNVVKTSPQTLSNLCLKINVKLGGINNILVPHQRSAVFQQPVIFLGADVTHPPAGDGKKPSITAVVGSMDAHPSRYCATVRVQRPRQEIIEDLSYMVRELLIQFYKSTRFKPTRIIFYRDGVPEGQLPQILHYELLAIRDACIKLEKDYQPGITYIVVQKRHHTRLFCADKSERIGKSGNIPAGTTVDTSITHPFEFDFYLCSHAGIQGTSRPSHYYVLWDDNRFTADELQILTYQLCHTYVRCTRSVSIPAPAYYARLVAFRARYHLVDKEHDSGEGSHVSGQSNGRDPQALAKAVQIHHDSLRTMYFA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: :* ...*.* **************:****************:***:**:******************************:***************** *****.*:********************:*** ****:*:*:****:: ***********************************************************************************************.*****************************************************************************************************************************************.:*******************************************************************************************************************************************************************************************************************************************************************************************************************:************************.*****************.******************************************************************************************:*****************:*:*:*******", "identical_positions": 820, "similar_positions": 30, "identity": "94.47%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110606-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TNF9-1", "uniprot_id": "F117A_MOUSE", "id": "Q7TNF9-1", "name": "Protein FAM117A", "aln": "MSGAAAGGRGGGSWGPGRGGAGGLRRGCSPPAPAGSPRVGLQPLRATVPFQLQQPHQRRDGGGRAASVPCSVAPEKSVCRPQPPQVRRTFSLDTILSSYLLGQWPRDADGAFTCCTNDKATQTPLSWQEPEGERASFCMHKRSASWGSTDHRKEITKLKQQLQRTKLSRSGKEKERSCPVQGDHAALGAGRASLPSHPPGPPVLRLSPCLHRSLEGLNQELEEVFVKEQGEEELLRILEVPDGHRAPAPPQNSSCDHS-LLLEPGNLTSSPSVPLASPQPPSQASREEHQGATEELASIHGNKASSPGNPAFLEDGSPSPVLAFAASPRPNHSYVFKREPPEGCERVRVFEEATSPGP-DLAFLTSCPDKNKVHFNPTG-SAFCPVSLIKPLFPSMGFIFRNCPSSPGSPLPTASPRAP-RKGPEASKASSLPSEPWQRSPPSEESVLFQSSLVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C073-1", "uniprot_id": "F117A_HUMAN", "id": "Q9C073-1", "name": "Protein FAM117A", "aln": "MAGAAAGGRGGGAWGPGRGGAGGLRRGCSPPAPAGSPRAGLQPLRATIPFQLQQPHQRRDGGGRAASVPCSVAPEKSVCRPQPLQVRRTFSLDTILSSYLLGQWPRDADGAFTCCTNDKATQTPLSWQELEGERASSCAHKRSASWGSTDHRKEISKLKQQLQRTKLSRSGKEKERGSPLLGDHAVRGALRASPPSFPSGSPVLRLSPCLHRSLEGLNQELEEVFVKEQGEEELLRILDIPDGHRAPAPPQSGSCDHPLLLLEPGNLASSPSMSLASPQPCGLASHEEHRGAAEELASTPNDKASSPGHPAFLEDGSPSPVLAFAASPRPNHSYIFKREPPEGCEKVRVFEEATSPGP-DLAFLTSCPDKNKVHFNPTG-SAFCPVNLMKPLFPGMGFIFRNCPSNPGSPLPPASPRPPPRKDPEASKASPLPFEPWQRTPPSEEPVLFQSSLMV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B629-1", "uniprot_id": "A0ACD6B629_DANRE", "id": "A0ACD6B629-1", "name": "", "aln": "MSCRSGVARVGN--------------------------QGLQPLRATVPFQLQNRTALR-------CKDTKTAECKTKGRPPKPTLRRTLSLDTLVGPYLQGNWPREPECQPVTCVNDKATQTPSSWIEETRGRRGGGGHKRSASWGSAEHLREVAKLRQSLQK-RSRHAPPAMDCDHTHQNIHNSQTHTPGSTQTMP-LIPLSRLAPRLRRSVEGLNLELEGVFVSET-AKEQHKILDVPDGHRAPVPVQRYSSASQ----------SDPSPAQLSPSHSPCTITETDMVVCGPLCP-----ASSP--PSCMSE-PPS------SSPRPNKTYVFQREPPEGCERVRVSEEAILPHQGNAPLQPSCPDPNKVNFTPHGGSAFCPVSLLKPLLPSMDLLFRGLSVSPVT---------------GCSAQSVAPLQPAGHAVGGYLSSALPDSL--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :. .* *. ********:*****: * . ..* *: ** :***:****::..** *:***:.: . *.******** ** * * . *********::* :*::**:*.**: : :: : . . . * .* : * *: **:* *:**:**** *** ***.* :* :**::*******.* * *. *.** . **. : * . . *.. **** *: :.: .** :*****::*:*:********:*** *** * : .: .**** ***:*.* * ******.*:***:*.*.::**. . .* : .* * * :* :: . . : .** ", "identical_positions": 164, "similar_positions": 96, "identity": "36.04%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110606-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2A699-1", "uniprot_id": "F1712_MOUSE", "id": "A2A699-1", "name": "Protein FAM171A2", "aln": "MPPPSGPGVLARLLPLLGLLLGGASRAPGKSPPEPPSPQEILIKVQVYVSGELVPLARASVDVFGNRTLLAAGTTDSEGVATLPLSYRLGTWVLVTAARPGFLTNSVPWRVDKLPLYASVSLYLLPERPATLILYEDLVHILLGSPGARSQPWVQFQRRAARLPVSSTYSQLWASLTPASTQQEMRAFPAFLGTEASSSG-NGSWLELIPLAAVSVHLLTGNGTEVPLSGPIHLSLPVPSEPRALAVGTSIPAWRFDPKSGLWVRNGTGVIRKEGRQLYWTFVSPQLGYWVAAMASPTSGLVTITSGIQDIGTYHTIFLLTILAALALLVLILLCLLIYYCRRRCLKPRQQHRKLQLSGPSD-NKRDQATSMSQLHLICGGPLEPTSS-GDPEAP-----PPGSLHSAFSSSRDLASSRDDFFRAKPRSASRPAAEPPGARTVEGAGLKSARSVEGPGGLEPSLDEYRRGPAGAAAFLHEPPSPPPSFDHYLGHKG--AAESKTPDFLLSQSVDQLARPPSLS-QPGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVGDE-ATPPEGSAAGPARPFPQPDPQRPLMQGHAG--------AGGDSGGG--EGWGGGRSAPVSGSVTIPVLFNESTMAQLNGELQALTEKKLLELGVKPHPRAWFVSLDGRSNSQVRHSYIDLQAGSGG---RSTDASLDS---GVDVHEARPARRRLPREERERAQLPAPPPP-APPRLALSEDTEPSSSESRTGLCSPEDNSLTPLLDEVVAPEGRAATVPRGRGRSRGDSSRSSASELRRDSLTSPEDELGAEVGDEAGDKKSPWQRREERPLMVFNVK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A8MVW0-1", "uniprot_id": "F1712_HUMAN", "id": "A8MVW0-1", "name": "Protein FAM171A2", "aln": "MPPASGPSVLARLLPLLGLLLGSASRAPGKSPPEPPSPQEILIKVQVYVSGELVPLARASVDVFGNRTLLAAGTTDSEGVATLPLSYRLGTWVLVTAARPGFLTNSVPWRVDKLPLYASVSLYLLPERPATLILYEDLVHILLGSPGARSQPLVQFQRRAARLPVSSTYSQLWASLTPASTQQEMRAFPAFLGTEASSSG-NGSWLELMPLTAVSVHLLTGNGTEVPLSGPIHLSLPVPSETRALTVGTSIPAWRFDPKSGLWVRNGTGVIRKEGRQLYWTFVSPQLGYWVAAMASPTAGLVTITSGIQDIGTYHTIFLLTILAALALLVLILLCLLIYYCRRRCLKPRQQHRKLQLSGPSDGNKRDQATSMSQLHLICGGPLEPAPS-GDPEAP-----PPGPLHSAFSSSRDLASSRDDFFRTKPRSASRPAAEPSGARGGESAGLKGARSAEGPGGLEPGLEEHRRGPSGAAAFLHEPPSPPPPFDHYLGHKG--AAEGKTPDFLLSQSVDQLARPPSLG-QAGQLIFCGSIDHLKDNVYRNVMPTLVIPAHYVRLGGEAGAAGVGDE-PAPPEGTAPGPARAFPQPDPQRPQMPGHSG--------PGGEGGGGGGEGWGAGRAAPVSGSVTIPVLFNESTMAQLNGELQALTEKKLLELGVKPHPRAWFVSLDGRSNSQVRHSYIDLQAGGGA---RSTDASLDS---GVDVHEARPARRRPAREERERAPPAAPPPPPAPPRLALSEDTEPSSSESRTGLCSPEDNSLTPLLDEVAAPEGRAATVPRGRGRSRGDSSRSSASELRRDSLTSPEDELGAEVGDEAGDKKSPWQRREERPLMVFNVK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F078-1", "uniprot_id": "E7F078_DANRE", "id": "E7F078-1", "name": "", "aln": "MRPQR----ASRFFALF-LFLCSAWRSLAKSLP-SPGPVEVLIKVQVFDNSDLSPLRESTVQVCGNQTILASNLVGEDGIVTLTFLYRPGTWVIVTASKHGFVTNSAPWHASRVPLYASVSLYLLPQRPATLLLYDDVVQLLLGSPGSRRQPWVQLQRRAIQPPLNNSQITLSAMLTSSRSQYELGGFPYPLAMDNNSTGTNSSWVELTALAAMCAQLTGPNGTEVQVSEPIHISIPLPSDS-PLKTATSVPVWRFEDKTGLWVRSGAGYIKKEDTQMTWSFVAPKLGYWLAAFPS-TSGSGLNTSGLRDITTYHTIFLLAILGAMALLVLILLCLLLYYCRRRCLKPRQHRRKMHLSSTLESSKRDQGTSTSHLNLISGGHMETASSTGDLNSSRDDFFKHGPTQRQHNSRTNADSKRGESFPLKATRSSNTGTRDLLLQDDYGKGYSSAEDSDDR-------KYNHHNAKDNQGYSSDPPSPPPLLPPFAGHYQDLNRDSKPPEYYASAG-DHLNRPSSVNTQPGQLIFCHSMEQMKESMYHSMVPTLVIPAHYMHLSSDLTAVEQAMERQQQLQHDMEGIQVSMTLPRQQNQKQQQQQARADNEEEESGKQADGSSEENWGSDQSS---APVRIPVLFNDSTIAQMNGELQAMTEKKLLELGVKPHPRAWFVSLDGRSNSLVRHSYIELSNEALRPPMGACNQTLDQRTEAIPTNSGKPSHRKLKEDGKVKEGGERKAHGKIYSKLPVIETPD-SSSESHSAMYSPEENSTAPLLDETAEVS-KGGTFPR-KGRSRDNSTRSSASEVHRDSVTSPDDDN-DDKDDDGENKKSPWQKREERPLMVFNVK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * :*::.*: *:* .* *: .** * .*.* *:******: ..:* ** .::*:* **:*:**:. ...:*:.**.: ** ****:***:: **:***.**:..::************:*****:**:*:*::******:* ** **:**** : *:..: * * **.: :* *: .** *. : .*:* *.**:** .*:*:..:* ***** :* ***:*:*:**:. .* ..**:*.***: *:*****.*:* *:**. *: *:**:*:****:**:.* *:* ***::** ********:**.*:***********:************::**::**.. : .****.** *:*:**.** :*.:.* ** ::. *. : ..* : *.*.: * *. :*...:. : . * ..*.. :. . ::.. . .: :****** : : ** :.*.*:: * . *:* **.*:. *.****** *::::*:.:*:.::*********::*..: *. . * : * .:. * *. : . .* :..*. *.**..::: ..* ******:**:**:******:*************************** ******:*. . : : :**. .: .:..:*::*: .: : : . .:*.: * .: *****::.: ***:** :*****.. . :..*.** :****.:*:******::***:***:*: : .*:. :******:************", "identical_positions": 376, "similar_positions": 265, "identity": "44.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110606-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QZ81-1", "uniprot_id": "AGO2_RAT", "id": "Q9QZ81-1", "name": "Protein argonaute-2", "aln": "-----------MYSG---AGPVLASPAPTTSPIPGYAFKPPPRPDFGTTGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGG-------------------------RNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKEYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CJG0-1", "uniprot_id": "AGO2_MOUSE", "id": "Q8CJG0-1", "name": "Protein argonaute-2", "aln": "-----------MYSG---AGPVLASPAPTTSPIPGYAFKPPPRPDFGTTGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGG-------------------------RNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UKV8-1", "uniprot_id": "AGO2_HUMAN", "id": "Q9UKV8-1", "name": "Protein argonaute-2", "aln": "-----------MYSG---AGPALAPPAPPP-PIQGYAFKPPPRPDFGTSGRTIKLQANFFEMDIPKIDIYHYELDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVFDGRKNLYTAMPLPIGRDKVELEVTLPGEGKDRIFKVSIKWVSCVSLQALHDALSGRLPSVPFETIQALDVVMRHLPSMRYTPVGRSFFTASEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFVCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQESGQTVECTVAQYFKDRHKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQEEISKLMRSASFNTDPYVREFGIMVKDEMTDVTGRVLQPPSILYGG-------------------------RNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTEVHLKSFTEQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFRHLKNTYAGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQMKNVQRTTPQTLSNLCLKINVKLGGVNNILLPQGRPPVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPNRYCATVRVQQHRQEIIQDLAAMVRELLIQFYKSTRFKPTRIIFYRDGVSEGQFQQVLHHELLAIREACIKLEKDYQPGITFIVVQKRHHTRLFCTDKNERVGKSGNIPAGTTVDTKITHPTEFDFYLCSHAGIQGTSRPSHYHVLWDDNRFSSDELQILTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDHQALAKAVQVHQDTLRTMYFA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AKD0-1", "uniprot_id": "A0A8M3AKD0_DANRE", "id": "A0A8M3AKD0-1", "name": "Protein argonaute-2", "aln": "MYPIGAAGATELFQGRPSSGSDVSAPASPP-APQEYVFKPPQRPDFGTMGRTIKLQANFFEMEIPKLEVYHYEIDIKPEKCPRRVNREIVEHMVQHFKTQIFGDRKPVYDGRKNLYTAMPLPIGRDKVELEVTIPGEGKDRSFKVAIKWMSCVSLQALHEALSGRLPNIPFETIQALDVVMRHLPSMRYTPVGRSFFTPSEGCSNPLGGGREVWFGFHQSVRPSLWKMMLNIDVSATAFYKAQPVIEFMCEVLDFKSIEEQQKPLTDSQRVKFTKEIKGLKVEITHCGQMKRKYRVCNVTRRPASHQTFPLQQENGQTIECTVAQYFKDKYKLVLRYPHLPCLQVGQEQKHTYLPLEVCNIVAGQRCIKKLTDNQTSTMIRATARSAPDRQDEISKLMRSANFNTDPYVREFGVMVRDDMTEVNGRVLQAPSILYGGRVRISSAQLSIWLNPCLIWSCLWLFQNKAIATPVQGVWDMRNKQFHTGIEIKVWAIACFAPQRQCTELLLKAFTDQLRKISRDAGMPIQGQPCFCKYAQGADSVEPMFKHLKYTYQGLQLVVVILPGKTPVYAEVKRVGDTVLGMATQCVQVKNVQKTTPQTLSNLCLKINVKLGGVNNILLPQGRPLVFQQPVIFLGADVTHPPAGDGKKPSIAAVVGSMDAHPSRYCATVRVQQHRQDIIQDLATMVRELLIQFYKSTRFKPTRIIYYRDGISEGQFNQVLQHELLAIREACIKLEKDYQPGITFVVVQKRHHTRLFCMDRNERVGKSGNIPAGTTVDTKITHPFEFDFYLCSHAGIQGTSRPSHYHVLWDDNHFTSDELQVLTYQLCHTYVRCTRSVSIPAPAYYAHLVAFRARYHLVDKEHDSAEGSHTSGQSNGRDQQALAKAVQIHQDTLRTMYFA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.* :*. ::.**... . *.**** ****** *************:***:::****:**********************************:************************:******* ***:***:*********:*******.:*****************************.*************************************************:*****************************************************************.***:**********::************************************************************:*********.***********:**:*:**:*.*****.******* :*****************************************: **:**:*********************************:*** ** ***********************************:****:****************************** *************************************.*************:******:*********************:****:*****:***:***************:*******:************ *:*********************** ****************************:*:*****:*********************************************************:********:***********", "identical_positions": 785, "similar_positions": 61, "identity": "87.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110607-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZB94-1", "uniprot_id": "GFRAL_RAT", "id": "D3ZB94-1", "name": "GDNF family receptor alpha-like", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MLVFIFLAVRLSSENESSSQTNDCAYF-------------------------MRQCLTDTDGCKQS------WRSMEDACLVS--GDSCKINNPLPCNLSIQSLVEKHFQFKGCLCTDDLHCTVNKIFG------------------------------------KKCTNKTDSMKKDNKYKRNLTT-PLYHDT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GFKQMQSCLEVTEACVGDVVCNAQLALYLKACTANGNLCDVKHCQAAIRFFYQNMPFNTAQMLAFCDCAQSDIPCQQSKETLHSKPCALNVVPPP-TCLSVIHTCRNDELCRTYYRTFQTECWPHVAGKCREDETCISMLGKQDLTCSGS----------DSCRAAYLGTFGTVLQVPCACRSITQGEEPLCMAFQHMLHSKSCFN-----------------------------------------YPTP-NVKDISSYE------RKHSKEITLTGFNSP-------------------------------------------------------FSG--------------------ELIYVVVCMVVTSGILSLVMLKLR---IPSKK-----RDPAPIEIAGAVIIQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6SJE0-1", "uniprot_id": "GFRAL_MOUSE", "id": "Q6SJE0-1", "name": "GDNF family receptor alpha-like", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MLVFIFLAVTLSSENESSSQTNDCAHL-------------------------IQKCLIDANGCEQS------WRSMEDTCLTP--GDSCKINNSLHCNLSIQALVEKNFQFKECLCMDDLHCTVNKLFG------------------------------------KKCTNKTDNMEKDNKDKWNLTTTPFYH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GFKQMQSCLEVTEACVGDVVCNAQLALYLKACSANGNLCDVKHCQAAIRFFYQNMPFNTAQMLAFCDCAQSDIPCQQSKETLHSKPCALNIVPPP-TCLSVIHTCRNDELCRTHYRTFQTECWPHITGKCHEDETCISMLGKQDLTCSGS----------ESCRAAFLGTFGTVLQVPCACRGVTQAEEHVCMIFQHMLHSKSCFN-----------------------------------------YPTP-NVKDISSYE------KKNSKEITLTGFNSF-------------------------------------------------------FNG--------------------ELLYVVVCMAVTCGILFLVMLKLR---IQSEK-----RDPSSIEIAGGVIIQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UXV0-1", "uniprot_id": "GFRAL_HUMAN", "id": "Q6UXV0-1", "name": "GDNF family receptor alpha-like", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------MIVFIFLAMGLSLENEYTSQTNNCTYL-------------------------REQCLRDANGCKHA------WRVMEDACNDSDPGDPCKMRNSSYCNLSIQYLVESNFQFKECLCTDDFYCTVNKLLG------------------------------------KKCINKSDNVKED-KFKWNLTT-RSHH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GFKGMWSCLEVAEACVGDVVCNAQLASYLKACSANGNPCDLKQCQAAIRFFYQNIPFNIAQMLAFCDCAQSDIPCQQSKEALHSKTCAVNMVPPP-TCLSVIRSCQNDELCRRHYRTFQSKCWQRVTRKCHEDENCISTLSKQDLTCSGS----------DDCKAAYIDILGTVLQVQCTCRTITQSEESLCKIFQHMLHRKSCFN-----------------------------------------YPTLSNVKGMALYT------RKHANKITLTGFHSP-------------------------------------------------------FNG--------------------EVIYAAMCMTVTCGILLLVMVKLRTSRISSKA-----RDPSSIQIPGEL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UV70-1", "uniprot_id": "A0A8N7UV70_DANRE", "id": "A0A8N7UV70-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------MRATRAAILLASHLLFGLVCIDASRSTDCISH-------------------------MAACVS-PHVCKSQ------QSTLRQTCQFK--DGTCRMTNAERCSGSLQMMLEGSPALRGCVCSLTDPCRTLQQLY------------------------------------SHCQPHWALKNKHLEASDHKAH-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALHADRPCLEEIAACLGEESCNRPMVPLLQECKAS----SCNQCTEAIRQFYSALPHSVAETLVFCECGAQDQQCQEMKALIHYGSCVSEQTQTPWTCLEALDSCFEDASCRQVFDGFLSKCFEAEESAFDSTSDWLYLLDP-DFFLGED----------VECRAAFVETVGSVLHHPCTCAGLHHHHQYKCDELKLIFQDKSLFKRSRRKDSLL------------------------------HGKPHEPNTQQQPSNEPSPDQQRIDGANLIHGQSNDS-------------------------------------------------------SNGQQATNESHVQQKLLSDQLLYLLIYISALMVLVLFIVSLVLHRVRRIHQAAGKPTFEDQQSKSLMMLSSVII------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4K7J4-1", "uniprot_id": "A0A0B4K7J4_DROME", "id": "A0A0B4K7J4-1", "name": "", "aln": "MTRFRIKNLKILSCCLSLWVVLFGGALHLAQGSEFPERECCDLTTTSTVGPLPMPPAALPTDKSLSSATTALETDLAIGRSGSTIKGVVAILNCILARQLCFEDPSCSAILEIIPRVCGPIPVSCSTVTVTKCQAALRTLQAFQFFRPTCLCKEPGMDPDCNHFRDFLFDHPCGFVLKKAEKDPYPIDALPTCNHALSVCQQERKCLKLFEDFKTHCKVR--DNKCKMENRDACHDSWTNLRLS--PMFGCICPNNHMKKRCDRIFNIVNHNPCVDRLIFFPNGLPKLKQPRPKAKPRPKPKPKSKPKPRQRHHGMNGTELMTNNIEYHDEPNGLSDPEDEANETVDEDPGGHGDEDEDEEDDDYDDRIRAEIYSNYPHYLHPPSWGINNPLVLASHSPHTLDDDDDVVVEVVANKKPPPVTLHHHNDELDHDVVVVVDAGPHSHSHPHSHTFYSHGDQSSTTGSGLPGPAPTIPSPPNTGTKMHKTAPLGDLVAGSDITHRTYTGPSMDERVRILGMDEKLHQRIFNDNLALIDTPLIAMGSGSGSGTVTTSVSGYGLGMGMGLSGSFNYLGSMHGVPSYPFNISGFHQRHMAAAAADNEPFDIIDTGLGYGGNGNAGVYYQSGQDVEVDLSTEIIKQHFQSTCHTALDTCREDPSCSSSLQPMLTHCELHR--CNRNACMSSLQAFYKGPHEDLNLDIAFCLCKKTS--SQQNGNGNRHDMCMIAQEKLHPVCAQRPPDNSNPASSNGIYYHPPPACHVVAD-SCKEDRECRLKLEYYEQACAVDSVTKKCAGRPSGCRTAMIGILGTMLRTTCACQGTDPQHLYQCVGWRRLLWMNPCVVEAQKDFHMKRLAELGFLTTTTTTTTTTTTTTTTTTTRAPPPPPPPTTTTTTTTSMQPRQTPRKPATHIFKDVITAKEKSEPTSVEHNYLDPPDSIPLPSVNVESGGNGGNDDYHNGNGNGHGNGNGNGRRKNGGKGRGGSVDFDDPVIFVDPRETTEFVGISITEPVTTTTTTMATTTTTQPPRNCVVQRPRQSDQLIREGSSKRIYSLDDVECSELCSCGESLILTCHALCVPFAPCRTALAFYSHASPAYQAFRGRCLCYSGRFICMKPPLGEYILPGGIFLLLGYSAADEALLRPHTNLGVQDAVRALQQYVTTYIDNQTQCTLTLFNMTEENIIIAARLPHDGKLKDIELLRKEKDECTAILKTISHQINSEHSELQSHRLLSIFKMSEVEVVWPESTSAAARSGHGPGQFAGCDRLLYAAMLALAYLSSWTTLRMSDVAT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .. :* * *: :. * .. *:: * * * : : *:* . : :. : .. : . : : .* :* : *. : * * . : * ::: **. . :.** * . .*: : * .* . : .. : . * . * : . . *::* : .*::*: *:* . * : :: :. . * .. . : . .: .* : :. .: ::. : . ", "identical_positions": 35, "similar_positions": 88, "identity": "2.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110607-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96P44-1", "uniprot_id": "COLA1_HUMAN", "id": "Q96P44-1", "name": "Collagen alpha-1(XXI) chain", "aln": "----MAHYITFLCMVLVLLLQNSVLAEDGEVRSSCRTAPTDLVFILDGSYSVGPENFEIVKKWLVNITKNFDIGPKFIQVGVVQYSDYPVLEIPLGSYDSGEHLTAAVESILYLGGNTKTGKAIQFALDYLFAKSSR---FLTKIAVVLTDGKSQDDVKDAAQAARDSKITLFAIGVGSETEDAELRAIANKPSSTYVFYVEDYIAISKIREVMKQKLCEESVCPTRIPVAARDERGFDILLGLDVNKKVKKRIQLSPKKIKGYEVTSKVDLSELTSNVFPEGLPPSYVFVSTQRFK---VKKIWDLWRILTIDGRPQIAVTLNGVDKILLFTTTS--VINGSQVVTFANPQVKTLFDEGWHQIRLLVTEQDVTLYIDDQQIENKPLHPVLGILINGQTQIGKYSGKEETVQFDVQKLRIYCDPEQNNRETACEIPGFNGECLNGPSDVGSTPAPCICPPGKPGLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQS---GRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKEGPPGDPGLPGKDGDHGKPGIQGQPGPPGICDPSLCFSVIARRDPFRKGPNY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z2G5-1", "uniprot_id": "A0A8M6Z2G5_DANRE", "id": "A0A8M6Z2G5-1", "name": "Collagen alpha-1(XXI) chain", "aln": "MGCKMRSMHFVFWCLYFMLLHLFCTAQDEDMRLSCRTAPSDLVFILDGSWSVDDINFEIVKKWLVNITMSFNIGQKFTQVGVVQYSDDPFLHIPLGKHFSSSDLIKAMESIEYMGGNTNTGRAIKFANDKLFALSERGPNGIAKIAVVLTDGKSQDEVLAAAEAARKKGIILFAIGVGSETEEAQLRAIANKPSSTYVFSVKDYKAIAKIREVIRQKLCEETVCPAKIAINSRDEKGFDILLHLNLAKKAKK-TQGSFYGSKAYQVTSRDDLSESTRMLFPGGLPPSYVFVATLKYKGSVAIEEWDLWRIQTKDEKPQMAVSLNGLDRTVMFTTTTSKTPSGTQTVVFTKSPAKKLFDEKWHQLRLLVTEEDVTLYVDDLEIETLALEPPDGIFINGKTQVGKYVSKETTVPFEVQKLRIYCDPEQNNRETACEIP---GVCANGPGDIDPTPEPCICPPGPPGTPGMTGERGKMGDPGQPGPAGADGKPGVPGFRGSPGIQGSPGIEGQRGADGHKGEKGSPGEAGDRGIPGLPGPPGKTGEKGSAGNQGIQGPPGKDGQTGEKGSRGLAGPPGYPGEPGAPGRDGKDGAPGAIGLKGDPGPPGIPGLDGREGHPGMPGIPGNDGQRGIKGEAGLSGSKGAKGIPGDAGEMGLPGMTGSSGQPGPKGNKGESGESGQAGPPGPEGKPGADGPSGQPGHPGMPGSLGMKGQRGDTGERGADGMKGERGDSGRPGGHGLPGAAGKKGEKGTAGEPGQSGLNGHQGLPGQRGQTGPSGPRGQSGEIGHPGPPGPEGRPGREMSEQHIQQICRDILRSEIPALLLSSQHSQHRSCEHCYTRVGPPGPVGTPG---PHGPRGFPGLSGSNGLQGQRGLPGRPGVPGMKGDPGEKGDKGSQGRSVIGDPGLPGPPGPTGPAGVGKPGQAGKPGSPGHEGKEGKRGQSGEPGQPGVCHPAMCYGAMIRRDPFSKGPNY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: : .:**: *:* ::* ******:*********:**. ************* .*:** ** ********* *.*.****.: *...* *:*** *:****:**:**:** * *** *.* ::*************:* **:***.. * ***********:*:************** *:** **:*****::******:***::*.: :***:****** *:: **.** * * *.*:***: **** * :** *********:* ::* . : ****** * * :**:**:***:*: ::****: . .*:*.*.*::. .*.**** ***:******:*****:** :**. .*.* **:***:**:*** .** ** *:********************** * * ***.*:..** ******* ** * .*: * *:** ** .* ***** *: *:**: *****:* ** *:*** * *: ****:**:** * .*.**. * :* :*.** *:.* **.:* ** ** ** .* ***.**** *: *:**:.*.** ** ** .*.**:**:*** * * *** * .*.:* ** ** .* ** * .*..* **.**.***.* .* .*..* :*:*** *..*:**: *:** * **::*: **:* :* ***.* .* ** :*: * * ***:* **** * * :* .* * **:**:**.*: * **** :*:****:***.*:*:* *::*:::*.** * .: *.*:** :: *.** *.** *.****:***.* :*: * *:****** *:** **.:*:***** . *: * ****** **.*:.* * .*.** **::*..** * .*:** **:*.*::*:..: ***** *****", "identical_positions": 553, "similar_positions": 213, "identity": "56.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110609-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LYZ4-1", "uniprot_id": "A0ABK0LYZ4_RAT", "id": "A0ABK0LYZ4-1", "name": "Glial cell line-derived neurotrophic factor", "aln": "MGFGPLGVNVQLGVYGDRIRGAAAGRDSKMKLWDVVAVCLVLLHTASAFPLPAGKRLLEAPAED--HSLGHRRVPFALTSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQAAALPRRERNRQAAAASPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCEAAETMYDKILKNLSR-SRRLTSDKVGQACCRPVAFDDDLSFLDDSLVYHILRKHSAKRCGCI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48540-1", "uniprot_id": "GDNF_MOUSE", "id": "P48540-1", "name": "Glial cell line-derived neurotrophic factor", "aln": "-----------------------------MKLWDVVAVCLVLLHTASAFPLPAGKRLLEAPAED--HSLGHRRVPFALTSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQAAALPRRERNRQAAAASPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCESAETMYDKILKNLSR-SRRLTSDKVGQACCRPVAFDDDLSFLDDNLVYHILRKHSAKRCGCI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P39905-1", "uniprot_id": "GDNF_HUMAN", "id": "P39905-1", "name": "Glial cell line-derived neurotrophic factor", "aln": "-----------------------------MKLWDVVAVCLVLLHTASAFPLPAGKRPPEAPAED--RSLGRRRAPFALSSDSNMPEDYPDQFDDVMDFIQATIKRLKRSPDKQMAVLPRRERNRQAAAANPENSRGKGRRGQRGKNRGCVLTAIHLNVTDLGLGYETKEELIFRYCSGSCDAAETTYDKILKNLSR-NRRLVSDKVGQACCRPIAFDDDLSFLDDNLVYHILRKHSAKRCGCI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ARX4-1", "uniprot_id": "A0A8M3ARX4_DANRE", "id": "A0A8M3ARX4-1", "name": "", "aln": "-----------------------------MKVCAVMLACALMLSCLSSVSNPSGHFHHSQPLEQRHHKLDLQRRPHKHLEPKSHSDGFPTPH-------LAFIHKSKRSPKRRGFFRSRLTRKK---ASRDER--------EKGKSRACALRQVQLTVSDLGLGYRSQEELIFSYCSGVCTNSLTNYDKILTSLTGGDKNILHSSPPTACCRPVEYDDDLSFLDDNLIYHTMGRHSARKCGCV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: *: .* ::* *:.. *:*: . * *: :.*. :* *. . .. .:.:* . * *:: ****.:: .* *:: *: *. ::**.*.*.* ::*.*:******.::***** **** * : * *****..*: .:.: .. *****: :*********.*:** : :***::***:", "identical_positions": 77, "similar_positions": 66, "identity": "31.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110609-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BW72-1", "uniprot_id": "KDM4A_MOUSE", "id": "Q8BW72-1", "name": "Lysine-specific demethylase 4A", "aln": "MASESETLN---PSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRTSYDDIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFNPPIYGADVNGTLYEQHVDEWNIGRLKTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRRFQPERYKLWKAGKDSMVIDHTLPTPEAAEFLKDSGG---------LTPRAGSEE-CPEEDVEAADQGEEG---------------------------------------DVKRSLAKHRIGTKRHR----------------------------------------------------------------------------------------------------------------------------VCLEIPQEVSQSELFPKE-------------------------------------------------------------------------------------------ELS-------------------------------------------------SGQYEMTECPATLAPVRPTHSSVRQVEDSLPFPDYSDPTEVKFE------------------ELKNVKLEEEDEEDEPEAAALDLSVNP-------------ASVGGRLVFSG-------------------------------------------------------------------------------SKKKSSS---------------SLGST------------------------------------------------------------------------SSQD-------------------SVSSDSET-------------------------------------------------------------AES-----------------------------------------------------------------------------VSCQGQEKTGVLTVHSYAR----------------------------------------------------------------------------------------------------------------------------------------------------------------GDGKAATGEPSVKKKRSAPR----------SISEQELAEVADE-----------------------------YMLS-------------------------------------------------------------------------------LEENKKTKGR----RQPLSKLPRHHPLVLQECGSDDETSEQLTPEEEAEETEAWAKPLSQLWQNRPPNFEAEKEFNEIMAQQAPHCAVCMIFQTYHQVEFGAFSQSCGDASEPAAQTQRTKPLIPEMCFTT-TGCSTDINLSTPYLEEDGTSMLVSCKKCSVRVHASCYGVPPAKASEEWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAERSPVDVSKIPLPRFKLKCVFCKKRRKRNAGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHKIPN-LERAKGALLSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDIVSQDCLQLGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELPKRVKSRLSVASDMRFNEIFTEKEVKQEKKRQRVINSRYREDYIEPALYRAIME", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75164-1", "uniprot_id": "KDM4A_HUMAN", "id": "O75164-1", "name": "Lysine-specific demethylase 4A", "aln": "MASESETLN---PSARIMTFYPTMEEFRNFSRYIAYIESQGAHRAGLAKVVPPKEWKPRASYDDIDDLVIPAPIQQLVTGQSGLFTQYNIQKKAMTVREFRKIANSDKYCTPRYSEFEELERKYWKNLTFNPPIYGADVNGTLYEKHVDEWNIGRLRTILDLVEKESGITIEGVNTPYLYFGMWKTSFAWHTEDMDLYSINYLHFGEPKSWYSVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPLMLKKYGIPFDKVTQEAGEFMITFPYGYHAGFNHGFNCAESTNFATRRWIEYGKQAVLCSCRKDMVKISMDVFVRKFQPERYKLWKAGKDNTVIDHTLPTPEAAEFLKESE----------LPPRAGNEEECPEEDMEGVEDGEEG---------------------------------------DLKTSLAKHRIGTKRHR----------------------------------------------------------------------------------------------------------------------------VCLEIPQEVSQSELFPKE-------------------------------------------------------------------------------------------DLS-------------------------------------------------SEQYEMTECPAALAPVRPTHSSVRQVEDGLTFPDYSDSTEVKFE------------------ELKNVKLEEEDEEEEQAAAALDLSVNP-------------ASVGGRLVFSG-------------------------------------------------------------------------------SKKKSSS---------------SLGSG------------------------------------------------------------------------SSRD-------------------SISSDSET-------------------------------------------------------------SEP-----------------------------------------------------------------------------LSCRAQGQTGVLTVHSYAK----------------------------------------------------------------------------------------------------------------------------------------------------------------GDGRVTVGEPCTRKKGSAAR----------SFSERELAEVADE-----------------------------YMFS-------------------------------------------------------------------------------LEENKKSKGR----RQPLSKLPRHHPLVLQECVSDDETSEQLTPEEEAEETEAWAKPLSQLWQNRPPNFEAEKEFNETMAQQAPHCAVCMIFQTYHQVEFGGFNQNCGNASDLAPQKQRTKPLIPEMCFTS-TGCSTDINLSTPYLEEDGTSILVSCKKCSVRVHASCYGVPPAKASEDWMCSRCSANALEEDCCLCSLRGGALQRANDDRWVHVSCAVAILEARFVNIAERSPVDVSKIPLPRFKLKCIFCKKRRKRTAGCCVQCSHGRCPTAFHVSCAQAAGVMMQPDDWPFVVFITCFRHKIPN-LERAKGALQSITAGQKVISKHKNGRFYQCEVVRLTTETFYEVNFDDGSFSDNLYPEDIVSQDCLQFGPPAEGEVVQVRWTDGQVYGAKFVASHPIQMYQVEFEDGSQLVVKRDDVYTLDEELPKRVKSRLSVASDMRFNEIFTEKEVKQEKKRQRVINSRYREDYIEPALYRAIME", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I3ITH4-1", "uniprot_id": "I3ITH4_DANRE", "id": "I3ITH4-1", "name": "[histone H3]-trimethyl-L-lysine(9) demethylase", "aln": "MASDSVSQSSQSPATRIMTFHPTKEEFKDFNRYIAYMESQGAHRAGMAKVVPPKDWKPRRTYDDIEDLVIPTPIQQVVTGQSGLFTQYNIQKKPMTVREFRKTANTDKFSNPRYADFEELERKFWKNLTFNPPLYGADVSGTLYDPDVMEWNIGRLNTILDMVERESGITIKGVNTPYLYFGMWKSTFAWHTEDMDLYSINYLHFGEPKSWYVVPPEHGKRLERLAKGFFPGSAQSCEAFLRHKMTLISPSILRKYGIPFEKVTQEAGQFIVTFPYGYHAGFNHGFNCAESTNFATQRWIDYGKLATLCSCRKDMVKISMDVFVHKFQPERYKLWKAGKDNVPIDHSKPTPEVAEIQKENEKGEISDSERAETLEERGEAEAGDQQKANTDDGEEDKAEAFSEKVVKRESDAGKEKAEAEVEKSVRDEEPSSTSEQISSSSPKQNTGQKRLRSSTDNEAKDDNQVKIEVEEVEKKKAKLGQNETDNNEEQSVSAEPDDEKAEETMETDTPPPQQQECMEAELSTSDPTSSSDITTQQREEESSDVTSSTQSINSVDEDVALGGDVASQSEDVTQSFVVQINPEDITPTDLTDAQPSNITSHPCSSDIPATSFMSVSSSNFSKHSISFAYTCDGTTEPSDSINLTPRVPSINVAHISDVQPEPSDIIVSLKQNSSANSTYTSDVQSDLSNVTVDPEHKPSINSTHIINVQSETSNITISSEHEPSISSTPMSDVQSETSFKYEPGNNSAYVCDVKPEHSDISMSPIYKPGVNFAHTSDVQPEPSECESCTNSDHICDVQSEANDIIINSKDEMSINSAHTFDVQPEPSDNTVSLTHKPDISSTSGSDVPSGPGDITDSLGYDPDFNSTHTGHVQSESNNSPKHKLPINSAHTYDVQSGPSDITDGHRFESEFNSTHICDVQSGPSDMSVNSKRKSSIDSAQIDDAQSDPSDISIGSKQEYSINSAQIDNVQSEPSDISIGSKQESSINSAQIDNVQSEPSNISISSKQETSINSTQIDDVQSEPSDISISSKNKLRINSAQIDDVQSAPSGISVSSEQETSIISAQVDDVQSEYSDISISSKHEPSINSTQTDDIQSEPIDISFGSKQESCINSAQMYDVQSEPSDISISSTQETSINSAQMYDVQLEPSDISISFKDKPSINSSQVDDVQSEPSDICFGSEQETCINSAQIYDVQSEPSNISFSSKQETSINSTQMYDVQSEPSDISISSNQETSINSTQMYDVQSEPSDISISSNQETSINSTQMYDVQSEPSDISISSNQETSINSTQMHDVQSEPSDISISSNQETTINSTQMYDVQSDPSDISISSKHKPSINSARMYDVQSEPSDISISSKHNPSIDSTQMFDVQSEPSDFSISSKHKPSIDSTQIYDVQSAPSGLTISYKQKTSINSAQMYEVQSEPSDFSVSSKRKPSIDSIHMYDDVQLKSSNFMVSRTPEPTYKIIPEPSSSVSVNVSGLSSVLASVSQGSVQHIFQRTLSPAEVLHVHSYAKGDYSDIEPRIQHERDSDSDSESQDDNKKEAERPAEAQYRLPRLPRHHPLIK-DSISDEELQDQAASEEDGLDGEAWARPLTQLWQNRPYNPDREREYNREMGLRPPYCSICMLFQAHHRSEG----AESEPAVVLRGGQMRTKPLIPERCFTITTEESADVQPSTAHLEEDGTSLLISCSLCSVRVHTSCYGVASGRVSKDWKCARCKANAFAESCCLCSLRGGALHRANNGKWVHVLCAVAVQEARFVNITERSPVDLSGIPLQRFKLKCYYCKRRMKKTLGCCVQCSHGRCPTSYHPTCAQAAGVIMHPDDWPFVVYVTCCRHKGPVQSERNKSAMRELSVGQRVICKHKNGRYYQCEVIQLTKETFYEVNFDDGSFSDNLFPEDIVNRDCAQLGPPPQGEVVQVRWTDGLVYGAKFVAAHVIQMYQVEFEDGSLLTAKRDDVYTLDEELPKRVKSRLSKASDMRFDGMFGEKKVQ-ESKRQRVINSRYRGDYIEPVIYRAIME", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***:* : . *::*****:** ***::*.*****:*********:*******:**** :****:*****:****:****************.******** **:**:..***::*******:*********:*****.****: .* *******.****:**:******:*************::************************* ************************************* :*:******:*******:*::************************:***:*** *.*****************::**************. ***: ****.**: *:. . . .* . ::: .::***. ::. * .*:. * ** * * *:::: ::* : :** * :** : .* :. *:* **.: . :::..::*: * * ::: ::.:** . * ::*:. :* :*..* * ** **:*** *:** **:: *:**:.** :*. :* .: :*.: :.: * .. : : ... . **. *:.. :: ** .* :*.* ::*** * : *.:*******: :. **:* .:* :.**:. : ****:**:******* * : *:*:*. *. :.*:*::**:**::*: * .. * ******** *** * *:*:: **.:*******:*:**. ******:*****...:.*::* *:**.***: *.***********:***:.:**** ****: *******:******:* *** ****** :**:* *:. *************::* :*******:*:********::** *** * ** *.*: .::.**:**.******:*****::**.*****************:*****.:** *:***.:*********** ********:* ************ *..********************* ******: :* **:*: *.*********** *****.:******", "identical_positions": 667, "similar_positions": 244, "identity": "33.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110613-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35764-1", "uniprot_id": "NPTXR_RAT", "id": "O35764-1", "name": "Neuronal pentraxin receptor", "aln": "-----------MKFLAVLLAAGMLAFLGAVICIIASVPLAASPARALPGGTDNASAAS-AAGAPGPQRSLSALQGAGGSAGPSVLPGEPAASVFPPPPGPLLSRFLCTPLAAACPSGAEQGDAAG----ERAELLLLQSTAEQLRQTALQQEARIRADRDTIRELTGKLGRCESGLPRGLQDAGPRRDTMADGAWDSPALLVELENAVRALRDRIERIEQELPARGNLSSS-APAPAVPTALHSKMDELEGQLLAKVLALEKERAALSHGSHQQRQEVEKELDALQGRVAELEHGSSAYSPPDAFKVSIPIRNNYMYARVRKAVPELYAFTACMWLR-------SRSGGSGQGTP------------------FSYSVPGQANEIVLLEAGLEPMELLINDKVAQLPLS-----LKDSNWHHICIAWTTRDGLWSAYQDGELRGSGENLAAWHPIKPHGILILGQEQDTLGGRFDATQAFVGDIAQFNLWDHALTPAQVLGIANCTGPLMGNVLPWEDKLVEAFGGAKKAAFDVCKRRAKA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99J85-1", "uniprot_id": "NPTXR_MOUSE", "id": "Q99J85-1", "name": "Neuronal pentraxin receptor", "aln": "-----------MKFLAVLLAAGMLAFLGAVICIIASVPLAASPARALPGGTDNASAAS-AAGGSGPQRSLSALHSAGGSAGPSVLPGEPAASVFPPPPVPLLSRFLCTPLAAACPSGAEQGDAAG----ERAELLLLQSTAEQLRQTALQQEARIRADRDTIRELTGKLGRCESGLPRGLQDAGPRRDTMADGAWDSPALLLELEDAVRALRDRIERIEQELPARGNLSS--APAPAMPTALHSKMDELECQLLAKVLALEKERAALSHGSHQQRQEVEKELNALQGRVAELEHGSSAYSPPDAFKVSIPIRNNYMYARVRKALPELYAFTACMCVR-------SRSGGSGQGTP------------------FSYSVPGQANEIVLLEAGLEPMELLINDKVAQLPLS-----LKDSNWHHICISWTTRDGLWSAYQDGELRGSGENLAAWHPIKPHGILILGQEQDTLGGRFDATQAFVGDIAQFNLWDHALTPAQVLGMANCTGPLMGNVLPWEDKLVEAFGGAKKAAFDVCKGRAKA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95502-1", "uniprot_id": "NPTXR_HUMAN", "id": "O95502-1", "name": "Neuronal pentraxin receptor", "aln": "-----------MKFLAVLLAAGMLAFLGAVICIIASVPLAASPARALPGGADNASVASGAAASPGPQRSLSALHGAGGSAGPPALPGAPAASAHPLPPGPLFSRFLCTPLAAACPSGAQQGDAAGAAPGEREELLLLQSTAEQLRQTALQQEARIRADQDTIRELTGKLGRCESGLPRGLQGAGPRRDTMADGPWDSPALILELEDAVRALRDRIDRLEQELPARVNLSAAPAPVSAVPTGLHSKMDQLEGQLLAQVLALEKERVALSHSSRRQRQEVEKELDVLQGRVAELEHGSSAYSPPDAFKISIPIRNNYMYARVRKALPELYAFTACMWLR-------SRSSGTGQGTP------------------FSYSVPGQANEIVLLEAGHEPMELLINDKVAQLPLS-----LKDNGWHHICIAWTTRDGLWSAYQDGELQGSGENLAAWHPIKPHGILILGQEQDTLGGRFDATQAFVGDIAQFNLWDHALTPAQVLGIANCTAPLLGNVLPWEDKLVEAFGGATKAAFDVCKGRAKA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O95503-1", "uniprot_id": "CBX6_HUMAN", "id": "O95503-1", "name": "Chromobox protein homolog 6", "aln": "---------------MELSAVGERVFAAESIIKRRIRKGRIEYLVKWKGWAIKYSTWE-PEENILDSRLIAAFEQK---ERERELYG-------PKKRGPKPKTFLLKARAQAEALRISDVHFS-----------------VKPSASASSP---KLHSSAAVHRLKKDIRRCHRMSRRPLPRPDPQGG--SPG---LRPPISPFSETVRIINRKVKPREPKR-NRIILNLKVIDKGAGGGGAGQG--------AGALARPKVPSRNRVIGKSKKFSESVLR---TQIRHMKFGAF-ALYKPPPAPLVAPSPGK----AEASAPGPGLLLAAP--------AAPYDARSSGSSGCP---------------------SPTPQSSDP--------------DDTPPKLLP------ETVSPSAPSWREPEVLDLSLPPESAATSKRAPPEVTAAAGPAPPTAPEPAGA-SSEPEAGDWRPEMSP-CSNVVVTDVTSNLLTVTIKEFCNPEDFEKVAAGVAGAAGGGGSIGASK----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DBY5-1", "uniprot_id": "CBX6_MOUSE", "id": "Q9DBY5-1", "name": "Chromobox protein homolog 6", "aln": "---------------MELSAVGERVFAAESIIKRRIRKGRIEYLVKWKGWAIKYSTWE-PEENILDSRLIAAFEQK---ERERELYG-------PKKRGPKPKTFLLKARAQAEALRISDVHFS-----------------VKPSASASSP---KLHSSAAVHRLKKDIRRCHRMSRRPLPRPDPQGG--SPG---LRPPISPFSETVRIINRKVKPREPKR-NRIILNLKVIDKGPGGGSTAQG--------TGALARPKVPSRNRVIGKSKKFSESMLR---TQIRHMKFGTF-ALYKPPPAPLAPSTAGK----ADVASSGPGLLLATPA-------AAPFDAHSSSSSGCP---------------------SPTLQSSDP--------------DDAPPKLLP------ETLSRSVPNWRESEVLDLSIPPEAAATGQRVPPDVTGAADQALHTALEPTGAGSSEPEAGDWRPEMSP-CSNVVVTDVTSNLLTVTIKEFCSPEDFEKVAAGVAGATGGGGGTGPSK----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "X1WBY5-1", "uniprot_id": "X1WBY5_DANRE", "id": "X1WBY5-1", "name": "", "aln": "---------------MELSAAGDRVFAAEAILKRRVRKGRMEYLVKWKGWAIKYSTWE-PEENILDERLVAAFEQK---EREQEMYG-------PKKRGPKPKTLLLKSRAQAESPRVPEFKHSRP---QPHSKPPPPPPPAAPSYTPTAPSNAKLQSGTAQPKLKKDIHRCHRMARRPLPRQDHTVG--PSGPFSSRPTVSAFSETVRILNRKVKPREVKK-GRVILNLKVLDKAENTAVANNKRTHVPSTQQSHFGRQKIPSRNRVIGKNRRFGEVSYRGIQPPIRGSGFPVFGKLFDSHSLKNAESGESRNSMTNNLSSSQSSKLLDVSKGQNRNEEPPPSNSSSEVSDGEPPSPRQTQSQHSSLQPKASSTKSPSTKAPDPTLHKLGTQPVASKNKDSASSALPSSPMFSSSSSASTSSEDNEHILDLSVPHEMDRRLRRRHP-FSGRHPLKVPEVPVSEEP-SEEEEDLDWRPDMTSRCANVVVTDITANLLTVTIKEFCHPPSASSPPCYSKNVSTQNDTQQPKQNPNKT-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P26017-1", "uniprot_id": "PC_DROME", "id": "P26017-1", "name": "Polycomb group protein Pc", "aln": "MTGRGKGSKGKLGRDNATDDPVDLVYAAEKIIQKRVKKGVVEYRVKWKGWNQRYNTWE-PEVNILDRRLIDIYEQT------NKSSG------TPSKRGIKKKEKEPDPEPESEE---DEYTFTEN---------------DVDTHQATTS------SATHDKESKKEKKHHHHHHHHHHIKSERNSG---------RRSESPLTHHHHHHHHESKRQRIDHSSSSNSSFTHNSFVPEPDSNSSS--------SEDQPLIGTKRKAEVLKESGKIG-----------VTIKTSPDGPTIKPQPTQQVTPSQQQ-----PFQDQQQAEKIAS-------------EAATQLKSEQQ----------------------ATPLATEA-----------------------------INTTPAESGAEEEEVANEEGNQQAPQVPSENNNIPKPCNNLAINQKQPLTPLSPRALPPRFWLPAKCNISNRVVITDVTVNLETVTIRECKTERGFFRERDMKGDSSPVA-----------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . * . * . .. . . * : . * * . . . : : : . . . . . : . : . : . : . . . . . . . . : .. . . . . : : . . : .. : * : . * ", "identical_positions": 7, "similar_positions": 54, "identity": "1.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110614-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5W041-2", "uniprot_id": "ARMC3_HUMAN", "id": "Q5W041-2", "name": "Armadillo repeat-containing protein 3", "aln": "MGKKIKKEVEPPPKDVFDPLMIESKKAATVVLMLNSPEEEILAKACEAIYKFALKGEENKTTLLELGAVEPLTKLLTHEDKIVRRNATMIFGILASNNDVKKLLRELDVMNSVIAQLAPEEEVVIHEFASLCLANMSAEYTSKVQIFEHGGLEPLIRLLSSPDPDVKKNSMECIYNLVQDFQCRAKLQELNAIPPILDLLKSEYPVIQLLALKTLGVIANDKESRTMLRDNQGLDHLIKILETKELNDLHIEALAVIANCLEDMDTMVQIQQTGGLKKLLSFAENSTIPDIQKNAAKAITKAAYDPENRKLFHEQEVEKCLVALLGSENDGTKIAASQAISAMCENSGSKDFFNNQ-GIPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSSKRDGAIANAATVLTNMAMQEPLRLNIQNHDIMHAIISPLRSANTVVQSKAALAVTATACDVEARTELRNSGGLEPLVELLRSKNDEVRKHASWAVMVCAGDELTANELCRLGALDILEEVNVSGTRKNKFSEAAYNKLLNNNLSLKYSQTGYLSSSNIINDGFYDYGRINPGTKLLPLKELCLQEPSDLRAVLLINSKS-YVSPPSSMEDKS-DVGYGRSISSSSSLRRSSKEKNKKNSYHFSAGFGSPIEDKSEPASGRNTVLSKSATKEKGWRK----------------SKGKKEEEKVKEEEEVMVVPKFVGEGSSDKEWCPPSDPDFSMYVYEVTKSILPITNIKEQIEDLAKYVAEKMGGKIPKEKLPDFSWELHISELKFQLKSNVIPIGHVKKGIFYHRALLFKALADRIGIGCSLVRGEYGRAWNEVMLQNDSRKGVIGGLPAPEMYVIDLMFHPGGLMKLRSREADLYRFI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2AU72-1", "uniprot_id": "ARMC3_MOUSE", "id": "A2AU72-1", "name": "Armadillo repeat-containing protein 3", "aln": "MGKKIKKEVEPPPKDVFDPITIESKKAATVVLMLKSPEEDILAKACEAIYKFALKGEENKATLLELGAVEPLTKLLTHEDKTVRRNAMMIFGILASNSDVKKLLRELEVMNSVIAQLSPEEEVVIHEFASLCLANMSVEYTGKVQIFEHGGLEPLIRLLSSSDPDVKKNSIECIYNLVQDFQCRTTLQELNAIPPILELLRSEYPIIQLLALKTLGVITCDKEARTMLKENQGLDHLTKILETKELNDLHVEALSVIANCLEDMDTMVLMQQTGSLKKVLSFAESSTIPDIQKNAAKAIAKAAYDPENRKVFHEQEVEKCLVTLLGSDSDGTKIAASQAISALCENLSCKEFFNTQ-GIPQIVQLLRSDNEEVREAAALALANLTTSSPANANAAAEADAIDPLINILSSKRDGAIANAATVLTNMATQEPLRAIIQNHEIMHALLGPLHSTNTLVQSTAALTVAATACDVEARTQLRNCGGLVPLVGLLHSKNDEVRRHASWAVMVCAGDEPMAVELCRLGALNILEEINRSLSRKNKFSEAAYNKLLNNNLSLKYSQTGYLSSSNIISDGFYDYGRINPGTKLLSLKELCLQELNDQRAILLVNNKS-DTSPPPSMEDKSSDVGYGRSISSSSSLRRGSKEKAN-------AIFGSPTEEKSEPASVRNTILSRAFTKEKGVSKKKSRLQLICSSYLLWKGKGKKEEEKVKEEEEILALPKFT-EGSPEKEWNPPPDPEFCVYVLEVTKSILPIVNLKEQIEVLAKYVADKMGGKIPKEKLADFSWELHISELKFQLKSNVVPIGYIKKGIFYHRALLFKALADKIGVGCSLVRGEYSRGWNEVKLVNEARKGMIGNLPPPEEYIVDLMFHPGNLLKLRSKEADLYRFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F083-1", "uniprot_id": "E7F083_DANRE", "id": "E7F083-1", "name": "", "aln": "MGKKVKKEAETCPKDVFDPLSIESKTATTAVLMLSSPEEEVLAKACEAIHKFAEKGDENKTCLMCLGAIEPLSLLISHEDKIVRRNAVMALGVMASNNEVKKHLKCLDVIPAIISKLSPEENVMVHEFATLCLASLSVDFSYKIQIFESNGLEPLIQLLSSPDPDVKKNSVECIFNLVQDVQNRAAVQRLNGLPPLLDLLRSEFSVIQQLALHTIEKITTDTETCVAFRNVQGFERILEVVAMKEFSDLHEGALRVILNCLEDTESMQLFQTMGGLEQLLQCVGTSTVAEVKANAVKAIAKMAQSSENRKILHERNIEKTLTDLLTQENESVRTAVCQAVATVSKNLSSRDTFRSLDGIRPIVQLLNSEGSELRMAAAEALSSLTNSNNLNAYAIYDAEGDRLLVRQLQDSCTGAAVYAAMALTNMASQEELRKSILAHEAMPALVELLHSTDNNILISAVQAVASLTCDAEARQELRNVGGLSALVQLLKSINAEIRRNASWAISVCANDEITASELCNVGALEILQEISLSSHRSNKFSQLALQKLLDSNLSLKYSLTGHLSSSDITTDGFYDPGQIRVGHQFPVLEDISKQVVNQHRATIAVNGKPQNQFIPKGPEEGKQDSPTDTTASSVLNGRRSSK--------------------------------TPSKTKGKGHKE---------------------EDEKKKEEDECKPHQKIM----VEETWSLPYDAAFHNLVKEAAESIMPLKDEVKMYTALAMLVCDAMGGQVEQQKLHDFLWELHISELKFEACSNIVLIGKIKKGTYFHRALLFKVLADRIGLSCSLIRGEYNRAWNEILIMGP--KKAYG-YSQPESYIIDLMHQPGNLMKSNSQAALIYQSI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:***.*. *******: ****.*:*.****.****::********:*** **:***: *: ***:***: *::**** ***** * :*::***.:*** *: *:*: ::*::*:***:*::****:****.:*.::: *:**** .******:****.********:***:*****.* *: :*.**.:**:*:**:**:.:** ***:*: *: *.*: . ::: **:::: ::: **:.*** ** ** ***** ::* :* *.*:::*. . .**:.::: **.***:* * ..****::**:::** *. ** .:.:..: *..**::::.:* ..:: *.. ** ::***.*:..*:* *** **:.**... ** * :*:. *:. *... ** . ** .***** ** ** * *: * *:: *:*::. : .*. :*:: :**.*** :*** *** .** **:* * *:*::****: ***.** * ***.:***:**:*:. * *.****: * :***:.******* **:****:* .***** *:*. * :: *:::. * .: ** : :*.*. * . *: . * . : ** . **.** : : ** ** : *:** ***:* *: :: * * *. * * *.::**:*: : : ** *.: ***:: ::** ** **********: **:: ** :*** ::*******.***:**:.***:****.*.***: : . * * . ** *::***.:**.*:* .*: * :*: :", "identical_positions": 399, "similar_positions": 253, "identity": "44.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110621-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ULU8-1", "uniprot_id": "CAPS1_HUMAN", "id": "Q9ULU8-1", "name": "Calcium-dependent secretion activator 1", "aln": "MLDPSSSEEESDE------------------------------------IVEEESGKEVLGSAPSG-----------ARLSPSRTSEGSAGSAGLGGGGAGAGAGVGAGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELER--LQKEEEERKKRLQLYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIMADEAFMNAVQSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAKFDAIYRGE-EDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNPDEQAAQIRRELDGRLQMADQIARERK-FPKFVSKEMENMYIEELKSSVNLLMANLESMPVSKG---GEFKLQKLKRSHN-------------ASIIDMGEESEN---QLSKSDVVLSFSLEVVIMEVQGLKSLAPNRIVYCTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRVILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWAIGKNVWKRWKKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPG-------LEGGRAFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFY----ADRAQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGN-----------------------------------RPDGIGTVTVEEKERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIRKCLEQAALVNYSRLSEYAKIEENQK-----------------DAENVGRLITPA-KKLEDTIRLAELVIEVLQQNEEHHAEPHVDKG--------------------------------------------------------------EAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLPNVNLPNV--NLPKVPNLPVNIP------LGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQTFIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQK--TSRSTDFRVPQSICTMFNVMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKLSRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIERLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTYETIRNRLTVEEATASVSEGGGLQGISMKDSDEEDEEDD------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q80TJ1-1", "uniprot_id": "CAPS1_MOUSE", "id": "Q80TJ1-1", "name": "Calcium-dependent secretion activator 1", "aln": "MLDPSSSEEESDE------------------------------------ILEEERGKDVLGSAASG-----------ARLSPSRTSEGSAGSAGMGG--SGAGAGVGAGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELER--LQKEEEERKKRLQLYVFVMRCIAYPFNAKQPTDMARRQQKISKQQLQTVKDRFQAFLNGETQIVADEAFMNAVQSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAKFDAIYRGE-EDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNPDEQAAQIRRELDGRLQMADQIARERK-FPKFVSKEMENMYIEELKSSVNLLMANLESMPVSKG---GEFKLQKLKRSHN-------------ASIIDMGEESEN---QLSKSDVLLSFSLEVVIMEVQGLKSLAPNRIVYCTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRVILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWTIGKNVWKRWKKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPG-------LEGGRAFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNAKGGNVPQLDAPISQFSGLKDADRAQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGN-----------------------------------RPDGIGTVTVEEKERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIRKCLEQAALVNYSRLSEYAKIEENQK-----------------DAENVGRLITPA-KKLEDTIRLAELVIEVLQQNEEHHAEPHVDKG--------------------------------------------------------------EAFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLPNVNLPNV--NLPKVPNLPVNIP------LGIPQMPTFSAPSWMAAIYDADNGSGTSEDLFWKLDALQTFIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQK--TSRSTDFRVPQSICTMFNVMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKLSRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIERLFDQWYNSSMNIICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTYETIRNRLTVEEATASVSEGGGLQGISMKDSDEEDEEDD------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62717-1", "uniprot_id": "CAPS1_RAT", "id": "Q62717-1", "name": "Calcium-dependent secretion activator 1", "aln": "MLDPSSSEEESDE------------------------------------ILEEESGKEVLGSAASG-----------ARLSPSRTNEGSAGSAGMGG--SGAGAGVGAGGGGGSGASSGGGAGGLQPSSRAGGGRPSSPSPSVVSEKEKEELER--LQKEEEERKKRLQLYVFVMRCIAYPFNAKQPTDMARRPRKISKQQLQTVKDRFQAFLNGETQIVADEAFMNAVQSYYEVFLKSDRVARMVQSGGCSANDSREVFKKHIEKRVRSLPEIDGLSKETVLSSWMAKFDAIYRGE-EDPRKQQARMTASAASELILSKEQLYEMFQNILGIKKFEHQLLYNACQLDNPDEQAAQIRRELDGRLQMADQIARERK-FPKFVSKEMENMYIEELKSSVNLLMANLESMPVSKG---GEFKLQKLKRSHN-------------ASIIDMGEESEN---QLSKSDVLLSFSLEVVIMEVQGLKSLAPNRIVYCTMEVEGGEKLQTDQAEASKPTWGTQGDFSTTHALPAVKVKLFTESTGVLALEDKELGRVILHPTPNSPKQSEWHKMTVSKNCPDQDLKIKLAVRMDKPQNMKHSGYLWTIGKNVWKRWKKRFFVLVQVSQYTFAMCSYREKKAEPQELLQLDGYTVDYTDPQPG-------LEGGRAFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLKPRAETCLSMDAPISQFY----ADRAQKHGMDEFISSNPCNFDHASLFEMVQRLTLDHRLNDSYSCLGWFSPGQVFVLDEYCARNGVRGCHRHLCYLRDLLERAENGAMIDPTLLHYSFAFCASHVHGN-----------------------------------RPDGIGTVTVEEKERFEEIKERLRVLLENQITHFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKTVIRKCLEQAALVNYSRLSEYAKIEEN-----------------------VGRLITPA-KKLEDTIRLAELVIEVLQQNEEHHAE---------------------------------------------------------------------AFAWWSDLMVEHAETFLSLFAVDMDAALEVQPPDTWDSFPLFQLLNDFLRTDYNLCNGKFHKHLQDLFAPLVVRYVDLMESSIAQSIHRGFERESWEPVN---------------------------------------------------------NGSGTSEDLFWKLDALQTFIRDLHWPEEEFGKHLEQRLKLMASDMIESCVKRTRIAFEVKLQK--TSRSTDFRVPQSICTMFNVMVDAKAQSTKLCSMEMGQEHQYHSKIDELIEETVKEMITLLVAKFVTILEGVLAKLSRYDEGTLFSSFLSFTVKAASKYVDVPKPGMDVADAYVTFVRHSQDVLRDKVNEEMYIERLFDQWYNSSMNVICTWLTDRMDLQLHIYQLKTLIRMVKKTYRDFRLQGVLDSTLNSKTYETIRNRLTVEERTASVSEGGGLQGISMKDSDEEDEEDD------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AB32TVX8-1", "uniprot_id": "A0AB32TVX8_DANRE", "id": "A0AB32TVX8-1", "name": "", "aln": "MLDPSSSEEESDG------------------------------------IVEEES-REVMAPQSGS-----------SRISPSRTSESSD---------------------------------RLQPSSRGSSARPTSPSPSAASE-EKEDVEK--LQREEEERKKKLQLYVFVMRCIAYPFNAKQPTDMARRQLKITKQQLQTTKDRFESFLKGDTQIVADEAFINAVQSYFEVFLKSDRVAKMVQTGGLSALDCREVFKRHIEKRVRSLPEIDGLSKETVLSSWMAKFDTIYRGD-EDPRKAQQRMTASAASELILSKDQLYEMFQQILGIKKFEHQLLYQACQLDNLDEQAAQIRRELDGRLQMADQIARAGK-FLKFVSKEMEAMYIEELKSSVNQLMANLESMPVSKG---GEFKLQKLKRGHN-------------TSIIDMGQEDEN---QLSKSDVVLSFTLEVVIMEVQGLKSLAPNRIVYCTMEVEGGQKLQTDQAEASKPTWGTQGDFTTTHPLPAVKVKLFTESTGVLALEDKELGRVVLHPTPNSPKQAELHKMTVTKACPDQDLKIKLAVRMDKPQNMKACGYLWAVGKNVWKRWKKRFFVLVQVSQYTFAMCSYREKKSEPQELLQLDGYTVDYTDPQPG-------LDGGRAFFNAVKEGDTVIFASDDEQDRILWVQAMYRATGQSHKPVPPTQVQKLNSKGKAAAQMDAPISQFY----ADRAQKHGMDEFISANPCSFDHASLFEMMQRLTLDHRLNDNFACLGWFSPGQVFVLDEYCARNGVRGCHRHLCYLGDLLERADAGHMIDPTLLHYSFAFCASHVHGNSQRGSELQGAGSKSGGKKESKKKRKCKTLLAPESTRPDGLGTVTVEEKERFEEIKERLRVLLENQITNFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPQEEVKAVIRKCLEQAAQINYQRITDYARVEGKKREMYDHPVYSLATQVMDLTIQNVANLATPA-KKLEHVIRLAELVIEVLHQNQDHHAEAAVTSTGDQ-----------------------------------------------------------SAFAWWSDLMVEHAENFLSLYGVDMDAALEIQSPESWDSFPLFQLLNDFLRTDYHLCNGKFHKHLQDLYAPLVVRYVDLMESSIAQSIHRGFERESWEPVKSLTSNLPNVNLPNVNLQIPKVPNLPVPVAGL---SVNLPQMPSFSTPSWMAAIYDSDNGSGTSEDLFWKLDALQTFIRDLHWPEEEFAKHLDNRMKLMSSDMIETSVKRTRGAFESKLTK--SSRSTDFRIPLSLCTMFNVMVDAKDQSAKLCAMEMGQEKQYHSQIDELIEESVKDMIALLVAKFVAILESVLAKISRYDEGTLFSSFLSFTVKAASKYVEVPKPGMDVADGYVTFVRHSQDILRDKVNEEVYIERLFDQWYTATMNLLATWLTERMDQQLHVYQLKILIRIVKKKYRDFRLQGVLDSTLNSKSYDTVRNRLTLEEATASVREGG-MQGISMKDSDEEDEED-------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NHE5-2", "uniprot_id": "CAPS_DROME", "id": "Q9NHE5-2", "name": "Calcium-dependent secretion activator", "aln": "MIDPSSSEEEGEDDAVPNVSSKGRLTNTTKGTSAVSIIGGSAGSVVGSNIPVSGSNTDLIGNQRQSNISSICNRNDVGNISVAALGSTSNKIEQICGNRADTGNLEVPSNGIPSGISQETLNQSVGSSRANSLPRPLSPSPSLTSEKHETAEPHGKHEREEEERKRRIQLYVFISRCISYPFNAKQPTDMTKRQTKISKQQLEIITQRFQAFLKGETQIMADEAFQNAVQSYHDVFLKSERVLKMVQSGASSQHDFREVFRNNIEKRVRSLPEIDGLSKETVLTSWMAKFDIILKGTGEEDSKRPSRMQQSLNSELILSKEQLYDMFQQILLVKKFEHQILFNALMLDSADEQAAAIRRELDGRMQRVGEMEKNRKLMPKFVLKEMESLYVEELKSSINLLMANLESLPVSKGNMDSKYGLQKLKRYNHSTPSFLKLILRSHGSLSKLEGDSEDGSTQLTKLDVVLTFQLEVIVMEVKGLKSLAPNRIVYCTMEVENGEKLQTDQAEASKPMWDTQGDFTTTHPLPVVKVKLYTENPGMLALEDKELGKVTLKPTPLSSKSPEWHRMIVPKNLPDQDIRIKIACRLDKPLNMKHCGYLYAIGKSVWKKWKRRYFVLVQVSQYTFAMCSYKEKKSEPSEMMQLDGYTVDYIEAASANLMFGIDLNGGRYFFNAVREGDSISFACDDENECSLWVMAMYRATGQSHKPTPPITQDKNSAMSKIQG-------------DADKARKHGMEDFISTDPCTFDHATLFKTLQNLTLEYRLNDPYASLGWFSPGQVFVLDEYCARYGVRGCYRHLCYLSDLLDRAEKQHMIDPTLIHYSFAFCASHVHGN-----------------------------------RPDGVGSITHEEKEKFSEIKERLRQLLEFQITNFRYCFPFGRPEGALKATLSLLERVLMKDIVTPVPPEEVRQMIKKSLETAALVNYTRLSNKAKIDEDLR----------------------GDVIVPAPKKLEDLIHLAELCVDLLQQNEEHYGELRKHDKMDKKKLLKEDEDVSGGHNESEVDLIDSTGLISASELATAASTDGSSFRYCMPTHAVYTPPVPTAFAWFSDLLVEHAEIFWSLFAVDMDRVLSEQAPDTWDSFPLFQILNDYLRTDDNLRNGRFHQHLRDTFAPLVVRYVDLMESSIAQSIHKGFEKERWESKG-INAALNPAALNNAAQALNTAALNPSMILCGKKDQVNFYVPKLPKQSNSTAANDEMRNGCATSEDLFWKLDALQSFIRDLHWPDAEFRQHLEQRLKMMAVDMIEQCIQRTDSSFQSWLKKNIAFISTDYILPSEMCAMVNVILDAKNQSFKLTTIDGIDLYKFHAKIDDQIDKANVAMTQGLSGKLMSVLESTLSKLARYDEGSLIGSILSFTNVSSS--------GKDLGQGYVNFFRNNMDQVRGKIADDLWTLHFFEQWYSQQINMLCNWLSERVDHALHYAQVASISHIIKKIYSDFELQGVLEDKLNSKAYQAVAQRMATEEATCALTMPDACEDEPCDEIREGEEEDNGDESTSNIPRGLPKPKVAAAQAAAVTNVVAGRVGNLLGKGIGGLSSKLGSGSWF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:********.: * . :::. . ..:* : .. * : .* . ** ***** .** .: : ::******:::*****: ***:***********::* **:****: .:**::**:*:***:***** ******.:*****:** :***:*. * * ****:.:********************:******* * :* *: * ** * *******:***:***:** :******:*::* **. ***** ********:* ..:: : * : *** **** :*:******:* *******:***** .:: ****** :: *: .: :.*: **:* **:*:* ***::***:******************.*:************ *.*****:***.**.*****:**..*:*********:* *:*** *.*..* *:* *.* ****::**:* *:*** *** .***:::**.***:**:*:****************:***:**.*::********* :. .. *:*** *****:***:: **.***:: *** ************.** :* .. . **:*:****::***::**.****:**: :*.***::**** ::.****************** *****:****** ***:**: ******:************** ****:*::* ****:*.******* *** ***:********************************** ***: :*:*.** ** :** *::: *::: . . : .** ****. *:**** :::*:**::*:.* ****:***:***** * **:.**** .*. *.*::********:***:**** :* **:**:**:* :********************:***:* **. **..*************:********: ** :**::*:*:*: **** .::** :*: * * : ***: :* .:*:*.**::*** ** ** ::: : ::*::**: *::: * * .*::::**..*:*::*****:*:.*:**** ::* * *:.:.**.*.*:. * :*.*: :::: ::*:***. :*::..**::*:* ** *: : :::** * **.*****:..****:*::: :*:: ** *.:: . :. . .: * :*** ", "identical_positions": 733, "similar_positions": 313, "identity": "45.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110621-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JUN2-1", "uniprot_id": "A0A0G2JUN2_RAT", "id": "A0A0G2JUN2-1", "name": "", "aln": "MTSLFTQEVHLSKRHEEIVSQRLMLLQKMKNKFGDQSTERAS-LQATETACRRNLQLLQDIDVAEKAFQTKLTPHPQPEMLSLETRYWASVEEHVPKWEQFLLGKALIQYVPVSGRLRMVLKNESWEWLLNSDRLI----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGD0-1", "uniprot_id": "CEP15_MOUSE", "id": "Q8BGD0-1", "name": "Centrosomal protein 15", "aln": "MASLFTQEIHLSKRHEEILSQRLMLLQKMKNKFGDENTERASLLQATETASRRNLRLLKDIDAAEEAFQTKLIPHPQPSMLSLETRYWASVEEHIPKWELFLLGRAP---YPIGAEN----QNE-VPFVQTEAKL-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBI5-1", "uniprot_id": "CEP15_HUMAN", "id": "Q9HBI5-1", "name": "Centrosomal protein 15", "aln": "MTSLFAQEIRLSKRHEEIVSQRLMLLQQMENKLGDQHTEKASQLQTVETAFKRNLSLLKDIEAAEKSLQTRIHPLPRPEVVSLETRYWASVEEYIPKWEQFLLGRAP---YPFAVEN----QNEAENTIQNEAQR-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EZM5-1", "uniprot_id": "E7EZM5_DANRE", "id": "E7EZM5-1", "name": "", "aln": "MASYTVEEFELSQKHEDILGKRALLLQQMEAHYEQQRAKRKQQFLMCQAAKQRNAQILKDLENVEKNLQTRQLLHPN--IISLETRYWASVERNLPEWEQYLLGKGQ---PPLSESEKKLKQQRLKTAQQDPSPAQCRGKPPRPKP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* .:*..**::**:*:.:* :***:*: : :: ::: . : ::* :** :*:*:: .*: :**: *. ::***********. :*:** :***:. *.. ::. ", "identical_positions": 40, "similar_positions": 47, "identity": "27.4%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110623-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IQX8-1", "uniprot_id": "ZN219_MOUSE", "id": "Q6IQX8-1", "name": "Zinc finger protein 219", "aln": "MEGSRPRILVGHLEP--SPP--------------------------------------------------------------AFDGELDLQRYSNGPGVSGTPGPGSPGMG----------------------------AVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPG-------------AQAFQCPHCGHRAAQRALLRSHLRTH----QPERPRSPAARLLLELEERALLREARLGRARSSGGMQSSPAAEGLARPQVPSSSAFRCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPPPP-PQQEPRSALEPEPEPEPRPEPDREANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPG----PGSAPARAPQPPDLSLLAYEPLGPALLLAPAPAPAERRE---------PPSLLGYLSVRAGEV--------RPNGEGADPGGGRSYGG---------------FRPLPSALPNRARRHR------TEEPEEEEEVVEAEEESWARGRSLGSLTSLHPNPG---------------------------EGSGQPAP------------AAGTQARSTATQ--EENGLLVGGTRSEAGRGATG----------------------------------KDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGP-PPEPPPPSQRGSLQPQSGAK---------------------PTQASATWVEGTASTRPPSSSTGPG----------------------------------------SRRKPASPGRTLRNG--------RGGEAEPLDLSLR------------AGPG-GEAGAGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRR--------------QPRAD--------------TSP---TYVRAPSGETPPSPPLEE---------------------------------EGSPGLSRSGEAG--LGGQER------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2Y4-1", "uniprot_id": "ZN219_HUMAN", "id": "Q9P2Y4-1", "name": "Zinc finger protein 219", "aln": "MEGSRPRAPSGHLAP--SPP--------------------------------------------------------------AFDGELDLQRYSNGPAVS----AGSLGMG----------------------------AVSWSESRAGERRFPCPVCGKRFRFNSILALHLRAHPG-------------AQAFQCPHCGHRAAQRALLRSHLRTH----QPERPRSPAARLLLELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPYCKGKFRTSAERERHLHILHRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEPEPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHASKLGPLRAPG----PASGPARAPQPPDLGLLAYEPLGPALLLAPAPTPAERRE---------PPSLLGYLSLRAGEG--------RPNGEGAEPGPGRSFGG---------------FRPLSSALPARARRHR------AEEPEEEEEVVEAEEETWARGRSLGSLASLHPRPG---------------------------EGPGHSAS------------AAGAQARSTATQ--EENGLLVGGTRPEGGRGATG----------------------------------KDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSGAGPGP-PPEPPPPSQRGS-APQSGAK---------------------PSPQPATWVEGASSPRPPSSGAGPG----------------------------------------SRRKPASPGRTLRNG--------RGGEAEPLDLSLR------------AGPG-GEAGPGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRR--------------PPQAD--------------ASP---PYARVPSGETPPSPSQEG---------------------------------EEGSGLSRPGEAG--LGGQER------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QQA8-1", "uniprot_id": "ZN219_DANRE", "id": "F1QQA8-1", "name": "Zinc finger protein 219", "aln": "MDSPPECMLALSCEPPLSPPSMPSLDHSPQFLPQSPQSTPSSPQTELYAPVSPCPLPEASLQDEEEEDEELSTPPSPTPAVALFPGELELGSPSSESSPPATPLAPFPSFGALEKAISSGQSTTCNDELDLQLFNNESIAVTGGTSSGPGLRFPCHVCGKRFRFQSILSLHARAHSLDRERRASAPYRTTHSKLQQNHESNSMIQNPLSGSFQKSMNEDMVPEEPLQTASSPQFLFEGTTALTPPLTEEAPISTSFSPLGHAQLEDNTPSPAAPAFRCHACKGKFRTASELARHVRILHNPYKCTMCPFSASQEERLAAHLQESHPPEDPPAEAVFPSG-----------------------------AIKAPPETPVPQMSVIPAFRCETCGQRFTQSWFLKGHMRKHKDSLDHKCQVCGRGFKEPWFLKNHMKVHLNKLGLKAGLGNLGPPGADQSKGPASSQVLGALYSNLLLARSMAGGGGSGSRTERSDASAGSSKSSILGYLGLPKDSSNGSCMERLQAVAQVAEMGNGGGRGGDSADGADQAAMWQLVARSLVAAQHNQQQQQQQRSHSLHQHPSSRATVAGEAKNMRAYLGGLGSREELDGSSAPWECPDCGKLFRSLQQVVAHAHVHVQKTQKGQSARGGMSREEDIINRVSGTQATGGAGQRTGENESRQEGKQLPSGVGASGSFHSVISHLSGQNGLRGSSPSSSSPRERVRGTGMKDCPYCGKAFRSSHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRNAMATSPNSPSPSLPSLTGS--PREGAKKRRLPSMSQQSSFGRVPGEAPSSRHTQSWTIGLSEKKEGSSASAHHREGDLESQYRGLSGMMGALLPSGLEQSWIGEVTLPKVPKVSRRKPQITSRMVSANGFQDKMTSQEGGFEPLDLSRRPLQDEGGVSQSGSGPSSGSKGGNDILNQCVFCPFRTSSVELMAMHLQVNHTSKSRRKRGAPISSNNHSQKLARPDRDPLALWKFLGVEDGVASPEDWVSARAENGVSPENRETEDNLELASGAMGSFRSRKKKPQMSEHVDEEDEEIDEEENDLEANGSFANVPQNQSRRAQSVSSDLPDDDLPKEEEGVLGE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:.. * *** * ***:* *. .. . . .:* ** . : . **** ********:***:** ***. . :* * .: *..* *. :: **.* ..*: : :* : * . .* * .:.. :: .. *::.**** *******::* **::***.*:** :*.*.:****.* * :* . : * *. .. * :*. :. : .. * ***:.*** *************** *:** * **** ************** .*** . * *.: ::.* ..:: *. * * :* . ...* * .*:****.: .. :. .: *: * * . ** *.* :* : :::: :.*... *. :: * .*** .*. .. *:.* .:*:** . * * ** *.: .* **:* ****:***:***:*******************************************.. ...* .*.*. ** ** *:.*** .: . :*. * :. : **.:. ***** ..* : . : * ****** * :**. *. * .. *::*:**** *.: ****:****:*: ::* :* * * :** .*. .* :* . * * .*. *. . .*.* ", "identical_positions": 288, "similar_positions": 189, "identity": "25.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110623-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TER5-1", "uniprot_id": "ARH40_HUMAN", "id": "Q8TER5-1", "name": "Rho guanine nucleotide exchange factor 40", "aln": "MEPEPVEDCVQSTLAALYPPFEATAPTLLGQVFQVVERTYREDALRYTLDFLVPAKHLLAKVQQEACAQYSGFLFFHEGWPLCLHEQVVVQLAALPWQLLRPGDFYLQVVPSAAQAPRLALKCLAPGGGRVQEVPVPNEACAYLFTPEWLQGINKDRPTGR-----LSTCLLSAPSGIQRLPWAELICPRFVHKEGLMVGHQPSTLPPELPSGPPGLPSPPLPEEALGTRSPGDGHNAPVEGPEGEYVELLEVTLPVRGSPTDAEGSPGLSRVRTVPTRKGAGGKGR-----------------HRRHRAWMHQKGLGPRGQDGARPPGEGSSTGASPESPPGAEAVPEAAVLEVSEPPAEAVGEASGSCPLRPGELRGGG--------GGGQGAEGPPGTPRRTGKGNRR-------------KKRAAGRGALSRGGDSAPLSPGDKE-------------------------------------------DASHQEALGNLPSPSEHKL--------------PECHLVKEEY------------------------------------------------------EGSGKPESEPKE-LKTAGEKEPQLSEACGPTEEGAGERELEGPGLLCMAGHTGPEGPLSD----------------TPTPPLETVQEGKGDNIPEEALAVSVSDHPDVAWDLMASGFLILTGGVDQSGRALLTITPP--CPPEEPPPSRDTLNTTLHYLHSLLRPDLQTLGLSVLLDLRQAPPLPPALIPALSQLQDSGDPPLVQRLLILIHDD--LPTELCGFQGAEVLSENDLKRVAKPEELQWELGGHRDPSPSHWVEIHQEVVRLCRLCQGVLGSVRQAIEELEGAAEPEEEEAVGMPKP-----LQKVLADPRLTALQRDGGAILMRLRS--------TPSSKLEGQGPATLYQEVDEAIHQLVRLSNLHVQQQEQRQCLRRLQQVLQWLS---GPGEEQLASFAMPGDTLSALQETELRFRAFSAEVQERLAQAREALALEEN---------ATSQKVLDIFEQRLEQVESGLHRALRLQRFFQQAHEWVDEGFARLAGAGPGREAVLAALALRRAPEPSAGTFQEMRALALDLGSPAALREWGRCQARCQELERRIQQHVGEEASPRGYRRRRADGASSGGAQWGPRSPSPS---------------LSSLLLPSSPGPRPAPSHCSLAPCGEDYEEEGPE----------------------------------------LAPEAEGRPPR------------------------------------------------AVLIRGLEVTSTEVVDRTCSPREHVLLGRARGPDGPWGVGTPRMERK-----RSISAQQRLVSELIACEQDYVATLSEPVPPPGPELTPELRGTWAAALSARERLRSFHRTHFLRELQGCATHPLRIGACFLRHGDQFSLYAQYVKHRHKLENGLAALSP-----LSKGSMEAGPYLPRALQQPLEQLTRYGRLLEELLREAGPELSSECRALGAAVQLLREQEARGRDLLAVEAVRGCEIDLKEQGQLLHRDPFTVICG---RKKCLRHVFLFEHLLLFSKLKGPEGGSEMFVYKQAFKTADMGLTENIGDSGLCFELWFRRR-RAREAYTLQATSPEIKLKWTSSIAQLLWRQAAHNKELRVQQMVSMGIGNKPFLDIKALGERTLSALLTGRAARTRASVAVSSFEHAGPSLPGLSPGACSLPARVEEEAWDLDVKQISLAPETLDSSGDVSPGPRNSPSLQPPHPGSSTPTLASRGILGLSRQSHARALSDPTTPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3UPH7-1", "uniprot_id": "ARH40_MOUSE", "id": "Q3UPH7-1", "name": "Rho guanine nucleotide exchange factor 40", "aln": "MEPEPVEDCVQSTLAALYPPFEATAPTLLGQVFQVVERTYQEDALRYTLDFLVPAKHLLAKVQQEACAQYSGFLFFHEGWPLCLHEQVVVQLAALPWQLLRPGDFYLQVVPSAAQAPRLALKCLAPGGGRVQELPVPSEACAYLFTPEWLQGINKDRPTGR-----LSTCLLSAPSGIQRLPWAELVCPRFVHKEGLMVGHQPSTLPPELPSGPPGLPSSPLPEEVLGTRSPGDGHNAPAEGPEGEYVELLEVTLPVRGSPVDAEAS-GLSRTRTVPARKSTGGKGR-----------------HRRHRAWMNQKGLGSRDQDGTRPPGEGSSTGASSDSPSGAEADPDATALQASEPPAEALGEAPESCLLS-GEAVGG----------VGQGAEGPPGTPRRTGKGNRR-------------KKRAAGRGAGSRGGEGTSLSPRDKE-------------------------------------------ETRQQEVLVSLPSPSEQEP--------------AECSLVKEK-------------------------------------------------------EDSGKQESESKEELKPADEKEPARPEDYEPPEEEIRESEKEELTPQCTAGSTGPEWFPSE----------------PSTQPLETVQNVKGDSLPEETPPVSVLDDPVVAWDLMASGFFVLTGGVDQTGRALLTITPPPPCLPEESSPSQETLSTALRYLHSLLRPDLQLLGLTILLDLRKAPPLPPALLPALSQLQDSGEPPLIQRLVILIHED--PPAELCGFQGAELLSEKDLKRVAKPEELQWDLGGHRDLSPNHWAEIHQEVARLCTLCQGVLTSVRQAIEELEGTAEPKEEEAVGMPEP-----LQKVLADPRLTALQRNGGAILMRLRS--------AHSSKLEGPGPAELYQEVDEAIHQLVRLSNLRVQQQEERQRLRQVQQVLQWLS---GPGEEQLASFSMPGNSLSVLQETELRFRAFSTEVQERLVQAREALALEED---------LTSQKVLDIFEQRLEQAESGLHRALRLQRFFQQAHEWVDEGSARLAGAGSGREALLAALALRRAPEPSAGTFQEMRALALDLGSPAALREWGRCRARCQELERRIQQQLGEEASPRSHRRRRADSASSAGAQHGAHSPSPS---------------LSSLLLPSSPGPRAAPSHCSLTPCGEDYEEEGLE----------------------------------------LAPETDGRPPR------------------------------------------------AVLIRGLEVTSTEVVDRTCSPREHVLLGRAGGPDGPWGIGTPRMERK-----RSISAQQRLVSELIACEQEYVTTLNEPVPLPGPELTPELRCTWAAALSVRERLRSFHGTHFLQELQGCAAHPLRIGACFLRHGDQFNLYAQFVKHRHKLESGLAALTP-----SVKGSMESSPCLPRALQQPLEQLARYGQLLEELLREAGPELSSERQALRAAVQLLQEQEARGRDLLAVEAVRGCEIDLKEQGQLLHRDPFTVICG---RKKCLRHVFLFEDLLLFSKLKGSEGGSETFVYKQAFKTADMGLTENIGDSGLCFELWFRRR-RAREAYTLQATSPETKLKWTSSIAQLLWRQAAHNKELRVQQMVSMGIGNKPFLDIKALGERTLSALLTGRAARTRASVAVSSFEHAGPSLPGLSPGACSLPARVEEEAWDLDVKQISLASETLDSSGDVSPGPRNSPSLQPPSPGSSTPALTSGGILGLSRQSHSRALSDPTTPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F579-1", "uniprot_id": "E7F579_DANRE", "id": "E7F579-1", "name": "", "aln": "MGSEAVEDCVQGALSSLYPPFESTAPPLLSQVFSVLESTYQHDSLRYLLDFFIPAKHLLHRLQQHACSQYLGCLFLHSGWPLCLGEKVVVQLSTLDWRLLRSTDFYLQVVPFSTRCPRLALKCLAPGGRNVQEVLVPESQHPLVFTSEWLHCINKERGCKREGGGCLDTCLVSTSDGVVRIPWEEVVYPKLLHNPSDLLQDKPD--PTDLSSGGLGLGWGGSSAQRD-SWSWDEEDDLPPDGNEADIEAALECLRRSSDGHLVADGAGDYVELLEPRGGPDGGADPKQRYLEMHGICKTKTLPLCRRGKAIRLRKGKG-RGYGRTESGARGGSLVRRDSNNNGKDGVVSCSDLATSRPLPRVIDLGRQRRSYSPSILHADEGARDPVGLECRSDCMDNPAKERKPGVGKERDGTGGTLHWEECQRKKISSRRCSTDASDANSLGDGQQDRSQSSHCGCDDKILASTLDIKEDIATSENQSNALDDGAIPLSADGKTEDTNKELAEPSRTRTRSLQDSSPSNALGSSDCAKRRNKHSDTTGEEKMDINLPPSGTVGAIGEKQVGKSENSVCPRGKEVKTGGFRAPRRKRKAKGGKGKAKSNGRVQQKGKGDQIISKNQTKATQPISHSSQSEEAPQLSTNSTGCEASSDDKTDAKSKAKDGESQSCTSSPDHSQNEVGLSQFAAHVESTSPPTHLKDLDLNLLQSGKLILTGTMDRLGRALVVTESH----LPEDGWTTNEMIKVLSCYYTITRPMVKEKGLTVIVDSRKSAPSELCLS-ALKLFKEQAATGLDSVLILTEESDESTQPYLEGIEMHTVRGTGILQQFVDKQHLPREMGGDFNHSHDDWLTFRLSLEQLTERCESALTLLGDALQSMETEPLPDCIKTVPLSVDKHRQLMTGILTDQRLTELQQRGGAWLAGLANGTSGLAQKSPDCKAAFAVTSDLYDSVDDALHRLVRSSNQRSRDLEALGRLAALVDKLDKCERDVEQIQDQLKDYKDPPLSLSRLTLKQHKFRSFRESAMDLHSETLVLLAEVESWSELDWSGLAAVLEKLPPVREKVRDMSHCLSDRWTQLDNTQRLLSTLTEASQWCDVVSSSSPSSSSTSPLSSLPPIPPSRFQDARALALDLGGGALLDLWSQTLERYQKTLAEFKSRILQAERGSSVAQGQEPDLGGRGRTPAPSSTSSLGDLEGEIEPDWCPGGEGGMQSWGSLASLFRPQNCSTLKIGEEKKKEGVNPGGGKFLQNLLHPAKKNPTDAPLPPKPPRKRHPSFDLQALLAPRRAGATSKPTESTSGQSSPLSWLGRKAMTDPILTAGVAAAVPGWRDPAAGGEAGGGGVLIRGVEVSSKEVADHTGFTRQHVLLSRTERGTGLERAGVTAQSKLYLQWCRLVSTERQYVAVLKGVEENYLPLLES------PDVPSALRGKAESLFCNWKSLSAFHSQLLLPAMEGALSQTLQQTDCFTKYKDQFLLYSQYIRMRPETDALIISQAADFFKMKLCSSLVPAPPFPQCLSAPLQRLQQYTQALEELAGLN--------PGSDSALSIIKHAHRHGEDLRASELISGCPIPVAERGDLVRQGELCVCGGGRRKKTGVRNVFLYQNFMIFTKHKTPNPGNSVYSFKHSIKTGEMGLTQSVGEDGLRFEVWVRQASRTRDCLTLQTASHQDRESWTHDIAQLLWTHAMHNTELCLKESLCMGISSKLLLDVTGAQSAELDSSSS---------------------LNDRVQSSCSDSSSVGSMKEDSPASQTRRSAEHTGHTQSSSPSTSV----------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .*.******.:*::******:***.**.***.*:* **:.*:*** ***::****** ::**.**:** * **:*.****** *:*****::* *:***. ******** :::.************ .***: **.. . :**.***: ***:* * *.***:*:..*: *:** *:: *:::*: . :: .:*. *.:*.** ** . : : * .: .: * :* *.: ** .. *:.: . . . *.. : ** :* :** * *. . :.. ..*.* .. * :. ..: * .*.* ...:. . . .. ... . *.. *:.* *:.* :*: :.* . : ..:. .*. ::: : ::. .*..**. . .:* ::: .** :::.: :: .: : .: . : . . . :. ** * .: ..: . : .: .. . . . : :*: ** ::*** :*: ****:. . * : : : ..* ::: ** :: **::::* *::.* .* **. :::.. . * . *:: ..* . * *:: : . *::... :.* ::**. : * ..* :: .: :* *:..* : :*::.:* . *. ::* :. : :*:* *** **: *** * * . : ..* .: **:.**:*:*:*** ** : :: * * : : *: . ::** .: * :** * .: :**:* .. : :: ** *. : : * ..:::.: . * *: . : *. .... : :: .* * ... **: ********. * * *.: * *: .::.:: : . : : . .. * .. *.*. ..: .* .. *.:** **: ::** : ***. * ..: .*****:**:*.**.*:* .*:****.*: * *.. .: * :*:::: *: * . *::*:. *.. *::.. ** . : :. : * :** :* ::*. ::.*: ** :: *** **:*::: * : : : : :. .*: ..* :*:.*. **::* :* : **** . :*:.:::. . :*.** * * : ** * : *:*:*:::. : * * :*. :*:***::.:::*:* * .: *.. : :*:::**.:****:.:*:.** **:*.*: *:*:. ***::* : : .** .****** :* **.** ::: :.***..* :**:.. . *.: : * . .:** .: * . * ..* :.* . : . **.. ", "identical_positions": 404, "similar_positions": 522, "identity": "22.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110623-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N6V9-1", "uniprot_id": "TEX9_HUMAN", "id": "Q8N6V9-1", "name": "Testis-expressed protein 9", "aln": "MAG-------RSLCLTRSSVPGTPFPPPVQQPSTPGP-------DLLALEEEYKRLNAELQAKTADVVQQAKEIIRDRQEVRSRPVSTQMKSCDDEDDYSLRGLLPSEGIVHLHSETKPKTKNIDPVNKVQNKLHSANKGRKTNSSVKLKYSDVQTA-DDVAIPEDFSDFSLAKTISKIEGQLEEEGLPEYI-DDIFSGVSNDIGTEAQIRFLKAKLHVMQEELDNVVCECNKKEDEIQNLKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKKYDGLQQQLSSVERELENKRRLQKQAASSQSATEVRLNRALEEAEKYKLELSKLRQNNKDIANEEHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMHIEAAKMLSFTEEEFMKALEWGNS--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D845-1", "uniprot_id": "TEX9_MOUSE", "id": "Q9D845-1", "name": "Testis-expressed protein 9", "aln": "MAG-------RSVRVPRRGSAGT----QSRGQLAAGR-------DLLAREQEYKRLNEELEAKTADLVRQAEEVIREQQEVRARPFSALTTSCKEEGGSSSRDLLSSEG-THPWTETKPKTKNTGPVNKIQNRLHSADKERKTNSSAKLKYPDAQTA-NDVAIPDDFSDFSLAKTISRIEGQLDEDGLPECAEDDSFCGVSKDIGTEAQIRFLKAKLHVMQEELDSVVCECSKKEDKIQDLKSKVKNLEEDCVRQQRTVTSQQSQIEKYKNLFEEANKKCDELQQQLSSVERELESKRRLQKQAASSQSATEVRLNRALEEAEKYKVELSKLRQTNKDITNEDHQKIEVLKSENKKLERQKGELMIGFKKQLKLIDILKRQKMHIEAAKMLSFSEEEFMKALEWGSS--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QU49-1", "uniprot_id": "F1QU49_DANRE", "id": "F1QU49-1", "name": "", "aln": "MADSTPRPALRPFKKPQTSYSERPSSTNLQSRTSSAPLKKPPQMDLLAKEEEYKRLNAKLEAKTAEIVRDAEKIMRDQNEVLSKPIFTCISIDSDSD-------LEVPGKPDVKKEPTSKQPTMMIMKNKSISAKSSKPSKPSSGNRKIQQKAPQTAVDDVAIPEDFGDFSLAKTISKIEDRVGDDLTEEHLQDDIMPSAGDEMGAEAQIRFLKAKLRVMQEELNRLSYACNKKDDENSTLTSKLKDLEEERARLQRTTNIQQTQVEKQKALAEESSRKSEGLQQQMAALQKELESMKRTFKQAASTHSATEVRLNRALEEAEKTKTQLNKLKQSTKDLSSQEHQKIEALQAENRKLERQKAELIVGFKKQLKLIDILKRQKMHYEAAKLLSFTEEEFMKALDWGKEVL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. *.. .: . . : :.. **** *:****** :*:****::*::*::::*:::** ::*. : . .:.. * * . .*...* . ::: . :*:. : :... *:: *** :*****:**.*********:**.:: :: * ** : ....::*:***********:******: : *.**:*: . *.*::*::**: * *** . **:*:** * * **:.:* : ****::::::***. :* *****::**************** * :*.**:*..**::.::*:***.*::**:***:**.**::**********:******* ****:***:********:**.. ", "identical_positions": 180, "similar_positions": 126, "identity": "44.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110623-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JZ38-1", "uniprot_id": "A0A0G2JZ38_RAT", "id": "A0A0G2JZ38-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGEEERGDGDPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALP----------------------------------------------------------------------LSAQIPALHRLLG---------------------APLKLEDCALQVSPSG---YYLDPELSLEEQREMLEGFYEEISKGRKPTLILRTQLSVRVNAILEKLYGSSGPELRRSLFSLKQIFQEDKDLVPEFVHSEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLVVKTALKLLLVFVEYSENNAPLFIQAVNAVASNTGTLPWANLVSILEEKNGVDPELLVYTVTLINKTLAALPDQDSFYDVTDAFEQQGMEALVQRLLGTAGTDVDLRTQLTLYESALRLEDGDMEEAAAAAAAGGRRERRKP--SSEEGKRSRRS-----------LEGGGCPVRTPEPGP------TGSASPVGSASFTDSTSPTSSAFSPTGPASG--LHTSVNLFP-----------------------------------------------------------------TISVGPS------------VDTSCERSV---------YKARFL----------------------ENVAAAETEKQAALAQGRAETLAG-------------------------------------------------------ATVDETDESSGTRELWDSSE--------------PASAPRPPQSPVS----------------------------------------------PIVLRTQRSLEPE------PKEPVSPRSPKT------------EPVQE-LPTHVPKLCIG-----DLDFSDLGEDEDQDTLNVESVEAGKASLVLSLPPSS--FSGGPPPPPPPPPPIIVSCPPPPPP----------------PPPPIMGSCLPPPPLAAPFPHSAL-----DGPRHPTKRKTVKLFWRELKPTGSPGCSRSRFGPCPTLWASLEPVSVDTARLEHLFESRAKDVLPTKKAGEGRRTMTIVLDPKRSNAINIGLTTLPPVHVIKAALLNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDVPLGPAENFLMTLASIGGLAARLQLWAFKLDYESMEREIAEPLFDLKVGMEQLVHNATFRCILATLLAVGNFLNGSQSSGFELSYLEKVSEVKDTVRRQSLLYHLCSLVLQTRPDSSDLYSEIPALTRCAKVDFEQLTENLGQLECRSQAAEDSLRSLAKHELSPALRARLTHFLAQCTRRVAMLRVVHRRVCNRFHAFLLYLGYTAQAAREVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERNKTRGRMITETEKFSGVAGEVPSNLSVPVAVGSGPGRGDADNHASMKSLLTSRPED--ATHSRRSRGMVQSSSPVTHTTVGPFTASPEETAAS------------------------------------GLPSDTSDEIMDLLVQSVTK-SSPRALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKAPGLEV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P9Q4-1", "uniprot_id": "FHOD1_MOUSE", "id": "Q6P9Q4-1", "name": "FH1/FH2 domain-containing protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGEEERGDGDPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALP----------------------------------------------------------------------LSAQIPALHRLLG---------------------APLKLEDCALQVSPSG---YYLDPELSLEEQREMLEGFYEEISKGRKPTLILRTQLSVRVNAILEKLYGSSGPELRRSLFSLKQIFQEDKDLVPEFVHSEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLVVKTALKLLLVFVEYSENNAPLFIQAVNAVASATGTLPWANLVSILEEKNGADAELLVYTVTLINKTLAALPDQDSFYDVTDALEQQGMEALVQRFLGTAGTDVDLRTQLTLYESALRLEDGDMEEAAAAAAAGGRRERRKP--SSEEGKRSRRS-----------LEGGGCPVRAPEPGS------TGSASPVGSTPSTGSAPPTNPAFSSTGPASGL-LRTSVNLFP-----------------------------------------------------------------TISVGPS------------VDSSCERSV---------YKARFL----------------------ENVAAAETEKQAALAQGRAETLAG-------------------------------------------------------ATVDDTDGSSGTRELWDSPE--------------PASAPRTPQSPVS----------------------------------------------RILLRTQRSLEPE------PKKPVSPPSPKA------------EPIQE-PPTCVPKLCIG-----DLDFSDLGEDEDQDTLNVESVEAGKASPFLSSLSPS--LSGGPPPPPPPPPPITGSCPPPPPPPLPPPATGSCPPPPPPPPPPIIGSCPPPPPLAAPFTHSAL-----DGPRHPTKRKTVKLFWRELKLTGGPGCSRSRFGPCPTLWASLEPVSVDTARLEHLFESRAKDVLPTKKAGEGRRTMTVVLDPKRSNAINIGLTTLPPVHVIKAALLNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDVPLGPAENFLMTLASIGGLAARLQLWAFKLDYESMEREIAEPLFDLKVGMEQLVHNATFRCILATLLAVGNFLNGSQSSGFELSYLEKVSEVKDTVRRQSLLYHLCSLVLQTRPDSSDLYSEIPALTRCAKVDFEQLTENLGQLECRSQAAEDSLRSLAKHELSPALRARLTHFLAQCTRRVAMLRVVHRRVCNRFHAFLLYLGYTPQAARDVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERNKTRGRMITETEKFSGVAGEAPNNLSVPVAVGSGPGQGDTDNHASMKSLLTSRPED--ATHSRRSRGMVQSSSPVSHTAVGPSAASPEETAAS------------------------------------GLPTDTSDEIMDLLVQSVTK-SGPRALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKAPGLEV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y613-1", "uniprot_id": "FHOD1_HUMAN", "id": "Q9Y613-1", "name": "FH1/FH2 domain-containing protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAGGEDRGDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALP----------------------------------------------------------------------LGAQIPAVHRLLG---------------------APLKLEDCALQVSPSG---YYLDTELSLEEQREMLEGFYEEISKGRKPTLILRTQLSVRVNAILEKLYSSSGPELRRSLFSLKQIFQEDKDLVPEFVHSEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSDTIQWLYTLCASLSRLVVKTALKLLLVFVEYSENNAPLFIRAVNSVASTTGAPPWANLVSILEEKNGADPELLVYTVTLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLEDGDIEEAPG---AGGRRERRKP--SSEEGKRSRRS-----------LEGGGCPARAPEPGP------TGPASPVGPTSSTGPALLTGPASSPVGPPSG--LQASVNLFP-----------------------------------------------------------------TISVAPS------------ADTSSERSI---------YKARFL----------------------ENVAAAETEKQVALAQGRAETLAG-------------------------------------------------------AMPNEAGGHPDARQLWDSPE--------------TAPAARTPQSPAP----------------------------------------------CVLLRAQRSLAPE------PKEPLIPASPKA------------EPIWE-LPTRAPRLSIG-----DLDFSDLGEDEDQDMLNVESVEAGKDIPAPSPPLPL--LSGVPPPPPLPPPPPIKGPFPPPPP----------------------------LPLAAPLPHSVP-----DSSALPTKRKTVKLFWRELKLAGGHGVSASRFGPCATLWASLDPVSVDTARLEHLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVHVIKAALLNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGPAENFLMTLASIGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLNGSQSSGFELSYLEKVSEVKDTVRRQSLLHHLCSLVLQTRPESSDLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLRSLAKHELAPALRARLTHFLDQCARRVAMLRIVHRRVCNRFHAFLLYLGYTPQAAREVRIMQFCHTLREFALEYRTCRERVLQQQQKQATYRERNKTRGRMITETEKFSGVAGEAPSNPSVPVAVSSGPGRGDADSHASMKSLLTSRPED--TTHNRRSRGMVQSSSPIMP-TVGPSTASPEEPPGS------------------------------------SLPSDTSDEIMDLLVQSVTK-SSPRALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGPGLEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QHW7-1", "uniprot_id": "A0A8M9QHW7_DANRE", "id": "A0A8M9QHW7-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MATITCRVQYLEDSDPFVCSNFPEPRRPPQYDFNEHLP----------------------------------------------------------------------LNEQIAGVHKLLE---------------------APLKLEECALQLASNG---NYLDLDSSLAEQRDDVEQLYDDVEKGKKPILILRTQLSVRVHSILEKLYNSHGPELRRSLFSLKQLFQDDKDLVPEFVISEGLTCFIKVGAEADHNYQNYILRALSQIMLFVDGMNGIVNHNETVQWLYTLCGSLSRLVVKTALKLLIVFVEYTESNSPLLIQAVNIVDGKRGVKPWTILIDILSAKNGSDTELLIYTMTLINKTLAALPDQDSFYDVTDCLEQLEMESIIQKHMTSSGTEGDLKQQFTIYEKALKCEDGEMDETAPN--VRKDRRKLTP--SEQEGRKSRRSSSHNLSDSSFRPASPTVSVSSNSPTPSE---VTRTASPQLSDSSSSPAPGSPVLTSPSSTTSGS-RTPPLALVTNGAESAAVPQQQHNLGRSFMSQYIAHMGISRRRLKKERSITEENSSIFSRASFSETDSAPETPTQTTADQPSRTVGKRVFKQQQADSVCPESVNRDLPVLRHYADTFLRSLAVSEWEKTKKSSALQEKPSESEAPTETEEQISLSTTTTESISGQESQGENVSRHTLEQPEDTTTAHNEAEGGLQHQGSTAEQHSTLSDDQRFVMDMLYSKSNTSSGALESPSLESALEGHGIRSMAVRLSRLQSSSSQPTEDPSRRAELESLGGTADAARAR-----------------------LAEEQKLKKLRPQYSIEAETHSQSLEKTLMTPLSRGS------------QDAWDKLQPSSRPLRIK-----DLDFSDLMEEEDIDVLDIDTFDTGLSNVIPPPPPPVPGLGSAPPPPPPPPPPGPAGLFSPPPPPPPPPPGFAGLASPPPPPPPPGGLSIPPPPGLFTTSPSQG-----LDPAFVKKRKTVKLFWKELKQSDSP--RKCKFG-RGTVWASLDKVDVDTAKLEHLFESKGKDLPVAKKGAEVKKAAISVLDPKRSNAINIGMTVLPAIHVIKSAILTFDEFAISKEGIEKILTMTPTEEEKQKIQEAQLANPDVPLGTAEQFLLTLSSISGLTARLQLWAFKLNYETLEKEIAEPLFDLKQGMEQLAKNKTFKRILATLLAIGNFLNSSRAKGFELGYLEKVTEVKDTVHRQSLLHHTCNFVVENYPDTTDLYSEIPAITRSAKVEFEQLSENLIQLERKCKTSWDNLKVVAKHETKPNLKNKMTEFLKDCTERIIILKVVHRRIINRFHSFLLYLGHPSYSVRDTKVTHFCKIISEFALEYRTTRERVLTQKRKRAVHRERTKTRGKLITETEKFSGAVTELSLDSSPSPVFSAVESEPAQEEHENMKNLLIANNDNKLLRRSRAVRKILTTAGDTSPVSPSLQWSDEEEPCDSDSAHTSPVESQSARDEDDEGVGRLSTHMSVAKEDSASSQDDATDEIMDRLVKSVTQNPTERASSPKTRKRSRLNRKSLRRTLKSGLSVEVVQALGLGSSNGKV-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JI78-1", "uniprot_id": "E1JI78_DROME", "id": "E1JI78-1", "name": "", "aln": "MSSYRSYTPWKTSLGSSYKPGSSTYGTSGDSTSRYTSLATPSSYRPSFSGGTYRLKRDPPPPVTTTPVSSYVSRYAKTEPKDAAPSERSSPVKRYTGNTTSSLGKYGRSRDPSPVALEHTNRNKSRDPSPVIDSARSKLGSTYRGGNTPTTSSSSSSATRNAYSSRYGAGSRISGNGSALSYLTTSDFHARTASRAKASREREREKEKEKEKEQEIEEKPSETSNGIDKSPAKQQVEKPENDEEPNETFITISVVTRATSPTLPGSTTVQRTRRIDPAKTIEKTIQRSSKRRETTDQEIQSDRLDDSTRYLRYSAGSSISSTYSPHRDRISSLRYSASPLNSSGSAKSSSVGEGKQIQPIPETVSPARTNGSVSSAKSSEALSPPRTNGNVSSGKSSEALSLPRSNGCSSKSTEAVSPPRTNGSLSSSKSTKSKLSPPKAIRLNSRQSSVENLVNKPPAPPSKADSPTKTCSSSSGSSAVKWPNKDFRKSSLNVGPTDRPRKSRTPSSGGESEDLPNGSSLERSPSAGSDGSLASGSSSKKSSKLSNGKVPGSLKPKSHKSCSETTTGNSSSATASASDSEQRVKSVKKQAKKKTTTKEGGAGKVANANKTNSTTESPPAVVDVVPATQTRLKKLSAVSNFFASRQQDANNEPIFLESSESSGEPEAHSLPVISAISGTSKISKISGISLTTDLRTNEPRTTPSSEAKQSPQTNSPSSSTRCPRETTTETGTRLPSSTTSTTQESSLTTTASLTTSEQDDPSWWQDTSLQINTASALDQNNRGEMPSYRLRHIDSGEEQAWWLRQDENGDDDDTLAEETLNTLDDDLQEPSKSTWWSQDDQDSSSQVKLMPRSRITPEKDAWWLQDEDEAAKSPIENGDLNNNNNSEPHVEVTLRLPSNGSQRSSKSSASKNGSNPKSGGANPWWLSGPARKMFNVQRVESGERAWWQEEAEEPPQEEKESEPPPVKPPTPPPRIIKHWESGERAWWLQDETESNQLPVQASSDDEEQPVLVVINQQESRDEVDLRLAPPTLESQELSNSFNFDAHSERPPPLGQCASPVRCPSPYDNIPRSQLQEPPPPPTTTLTSLQPRFSPQTRRAGEKLFISRHQNIDELLGGACRPLSPLFYGNSNPAESELTPLAGKNMFLLEEVTPDQVRIHDSTAQLPVIQRMQRDVEWLDNGSNFYEPPEQRQHQPPRRIDDAAIQVYKDGDYGAYLDLESSLAEQAEEIEG----VNVSRKNSLVVRTQLNVRVQAIIEKLLSAQGSDLRRALFSLKQVFQEDKDLVHAFVALGGLNCLVRVGNCADQNYQNYILRALGQVMLYVDGMNGVMKHEPTMQWLYSLIASNYRSVVKTALKLLLVFVEYAESNCYVLVSAIHAVDASQGTLPWSNIMRLLKDYDNADAELVIYATSLINKTLAGLNDQDSFYDESDLLEQQGMETVIQRYMSKPGTDLDLLDQLQLYEAVLKFEDGESDGQRLPQNSMRKTQRYRPGANTTERRKSRRHS----------TDNSPASLTKVLPTTVLRMTPTQATVDEDSSGSTNSTEFSGGLFNEKKPRDGAGVTPGLRRRRERAERHKSFLKEQQEAAANGIFAALEQREGLGQIVTAIPATIQTGDSPPQSLQHEVPPCNNISGITNISNNN-----------VSNLSCNDTPNNSLLVMSPSKQLLTGSHSISIINN-------SFDKASNNNQSEFLTKKNLFRERNSTVINGIMKNIQQTDSAYKKYENEANRLNN-----YYSQSPKHQIHQPIQPTPEVLLSPKKTLNASGFDFTPAPLSSTPVKCDVPPEPEPLSPVKKPAAAPPPPPPPPPPPPPPPGWWHAPIYNSPQARTLTSTNPELLPHPVDPSDMESEDQQLLLQLKRDHTVKDLTQKLSNLPMSPTQDSANRALVGDMSGLISKAKEGLAKSKSKGEISRSSSVDQDVKKSEPKKSENELHWEELVRNMTRPLNLCDLDFTDLRDDDEKDVLAPRSLGAGIPPPPPPLGG-AIAPPPMMPPSLAPPPMYGYGGSLTNSVNSLNGSINGELVNGNNTIKKNKKTVKLFWKEVREDMIP----QVVG--KTIWDELPDANVDTQKLEHLFESRAKDLMTKKQQELNKSKEIIVLDHKRSNAINIAITKLPPPRAIKTAILKMDATVVTREGIDKLLNMLPTDEERGKIQEAQLSNPELPLGSAEQFLLTLASISELEARLKLWAFRLDFDNSEKEIAEPLMDLKQGIEILRQNRTFRSILSTLLSVGIFLNGAPVKGFQIEYLAKVPEVKDTVHKHSLLHHLCHMVMESSSDTSDLYSEIGPITRASKADFTDLAHNLNQLEAECKACWDRLKLIAKHDCPPPLKQKLVDFLADCAERIIILQIVHRRVMNRYRKFLLWLGMPQHSVAESRPNEFCRTLSEFALEYRTTRERVQQQLEKKANHRERNKTRGKLIIDMAKFK--------------------TKDDVADDELKKLLDTSSADQADGTLTWRRRRAEQLRSPITR-------QSEEQ------------------------------------------FTDGDDEILESLVKTATKAPGTRTTPRERKRTRHADRKSLRRTLKNGLTEEEKQHVAALIQTY---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : *: . * : ::: ** .* : * *:. :::: .* ::::.*:*: .* *** : ** ** : :* :. .:* *::****.***::*:*** .: *.:***:******:**:***** ** **.*:::** **:***.******.*:**:**** *:: *. *:****:* .* * *********:*****:*.*. ::: *:: * . *. **: :: :*. :. *.**::*: :*******.* ******* :* :** **:::*: : ..**: ** *: :** .*: ***: : .: * . * ::*** . . * . * .: . :..: : . . .* . : * . : . : : .. :* : * .:: . : :. . * .: .:. .. * *: : . : : : * . : . : * * *... .:. : *. : . . : . .* . . .**** . * . .::*******:*:: .* *:* .* ..*** :*******:.*:: *: : *** ********.:* **. :.**:*:*.:* .::::**:*:*.* **:**: **:****:**::***.**:**:**:**. * ***:****:*:::. *:******:*** *:* * :* **: **:***::* ***.: .**:: ** **.******:::***:* * :*::. .:::****** .:**.:*.:* :*:.** *** ..::. : *: :***: * *: ::..** :*:.*: :*::****: **:: ***:** . :. : : .**: : ******** **** * .*:* :***.****::* : **. . .. * * : :: . * . . *: * ***:: **::.*: . *: . . :: : :*********.** : * :. ", "identical_positions": 379, "similar_positions": 331, "identity": "14.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110623-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NWW5-1", "uniprot_id": "CLN6_HUMAN", "id": "Q9NWW5-1", "name": "Ceroid-lipofuscinosis neuronal protein 6", "aln": "-MEATRRRQHLGATGGPGAQLGASFLQARHGSVSADEAART-APFHLDLWFYFTLQNWVLDFGRPIAMLVFPLEWFPLNKPSVGDYFHMAYNVITPFLLLKLIERSPRTLPRSITYVSIIIFIMGASIHLVGDSVNHRLLFSGYQHHLSVRENPIIKNLKPETLIDSFELLYYYDEYLGHCMWYIPFFLILFMYFSGCFTASKAESLIPGPALLLVAPSGLYYWYLVTEGQIFILFIFTFFAMLALVLHQKRKRLFLDSNGLFLFSSFALTLLLVALWVAWLWNDPVLRKKYPGVIYVPEPWAFYTLHVSSRH-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5J5-1", "uniprot_id": "A0ACD6B5J5_DANRE", "id": "A0ACD6B5J5-1", "name": "", "aln": "MPTVIRKRQNCG--------LSTTFLS-RCGSRELRESCLTPDQFHSCFWCCFTLQNWLLDIGRPVITIFCPLDWFPLNKPSAADYCHMLYNITTPFLLLKLMERSPKTLPRSAMYLCIITFVMGSSIHLLGESINQRLLISGYQTHLTLRENPIIKSITPHTLIDSFELLQYYDESLGLCMWYVPLFLILFLYFTGCFTIVKAEKKMPVSAWILLGPSGLYYWYLVTEGQIFIPFIFTFFAMMATVLHQKRKGFLPDSNGLFLLYSFSISLFLVSVWVACLWNDKVLRKKYPGVMYIPEPWALYTLHLRDKHTTLTD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *:**: * *.::**. * ** . *:. * ** :* ******:**:***: :. **:********..** ** **: ********:****:***** *:.** *:**:****:*:*:*:***:**** **::*******.:.*.********* **** ** ****:*:*****:**:**** ***. :* .* :*:.***************** ********:* ******* :: *******: **:::*:**::*** **** *********:*:*****:****: .:* ", "identical_positions": 198, "similar_positions": 63, "identity": "62.26%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110624-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P768-1", "uniprot_id": "B4GT3_RAT", "id": "Q6P768-1", "name": "Beta-1,4-galactosyltransferase 3", "aln": "-------MLRRLLERPCTLALLV--------GSQLAVMMYLSLGGFRSLSALFGRDPG-------------------------------------PTFDYSHPHDVYSNLS-HLPGAPGAA---GAPLAQVLPDCPERSPFLVGPVSVSFSPVPSLAEIVERNPRVESGGRYRPAGCEPRSRTAIIVPHRAREHHLRLLLYHLHPFLQRQQLAYGIYVIHQAGNGTFNRAKLLNVGVREALRDEEWDCLFLHDVDLLPENDHNLYVCDPRGPRHVAVAMNKFGYSLPYPQYFGGVSALTPDQYLKMNGFPNEYWGWGGEDDDIATR-----VRLAGMKISRPPTSVGHYKMVKHRGDKGNEENPHRFDLLVRTQNSWTQDGMNSLTYRLLARELGPLYTNITADIGTDPRGPRAPSGPR--YPPGSS-----QAFRQEMLQRRPPARPGPLPTAN---HTAPHGSH----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YY2-1", "uniprot_id": "B4GT3_MOUSE", "id": "Q91YY2-1", "name": "Beta-1,4-galactosyltransferase 3", "aln": "-------MLRRLLERPCTLALLV--------GSQLAVMMYLSLGGFRSLSALFGRDPG-------------------------------------PTFDYSHPHDVYSNLS-HLPAAPGAA---GAPPAQALPYCPERSPFLVGPVSVSFSPVPSLAEIVERNPRVESGGRYRPAGCEPRSRTAIIVPHRAREHHLRLLLYHLHPFLQRQQLAYGIYVIHQAGNGTFNRAKLLNVGVREALRDEEWDCLFLHDVDLLPENDHNLYVCDPRGPRHVAVAMNKFGYSLPYPQYFGGVSALTPDQYLKMNGFPNEYWGWGGEDDDIATR-----VRLAGMKISRPPTSVGHYKMVKHRGDKGNEENPHRFDLLVRTQNSWTQDGMNSLTYRLLARELGPLYTNITADIGTDPRGPRSPSGPR--YPPGSS-----QAFRQEMLQRRPPARPGPLPTAN---HTAPRGSH----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60512-1", "uniprot_id": "B4GT3_HUMAN", "id": "O60512-1", "name": "Beta-1,4-galactosyltransferase 3", "aln": "-------MLRRLLERPCTLALLV--------GSQLAVMMYLSLGGFRSLSALFGRDQG-------------------------------------PTFDYSHPRDVYSNLS-HLPGAPG-----GPPAPQGLPYCPERSPLLVGPVSVSFSPVPSLAEIVERNPRVEPGGRYRPAGCEPRSRTAIIVPHRAREHHLRLLLYHLHPFLQRQQLAYGIYVIHQAGNGTFNRAKLLNVGVREALRDEEWDCLFLHDVDLLPENDHNLYVCDPRGPRHVAVAMNKFGYSLPYPQYFGGVSALTPDQYLKMNGFPNEYWGWGGEDDDIATR-----VRLAGMKISRPPTSVGHYKMVKHRGDKGNEENPHRFDLLVRTQNSWTQDGMNSLTYQLLARELGPLYTNITADIGTDPRGPRAPSGPR--YPPGSS-----QAFRQEMLQRRPPARPGPLSTAN---HTALRGSH----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AMT1-1", "uniprot_id": "A0A8M3AMT1_DANRE", "id": "A0A8M3AMT1-1", "name": "Beta-1,4-galactosyltransferase", "aln": "----MMVCCGRALDSPCTLALLV--------GFQFAFVLYFSLGGFRGLVSVLLHSTE-------------------------------------PEIDYSRPHDVYTNLTSLLLHHPG-----PSGAEQQLRDCSLPSPLLVGPVSVHLSSPPSLEEIKEKNPLVTLGGHYRPPDCEPRHHTAIVVPYRNRQSHLRTLLYHLHPFLQRQQLHYAIYIVHQSGNSTFNRAKLLNVGVREVLKEEDWSCIFLHDVDLLPENDHNTYTCHPQNPTHLSVAMDKFRYRLPYSQYFGGVSAVTPQQYLKMNGFPNQYWGWGGEDDDIAARPRRDQVRLSGMKIMRPPLAIGHYKMIKHKGDQGNEQNPRRFDLLKRTRLNWRSDGLNSLTYELLSKKLEPLYTNLSVNIGDDPHHPPGKTPPRRVDPPLTSPNKTKTEKVGVVIANATKVEPALLKASNDSSNIVQKASLNQAG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KN92-1", "uniprot_id": "B4GTA_DROME", "id": "Q7KN92-1", "name": "Beta1,4-N-acetylgalactosaminyltransferase A", "aln": "MYLFTKANLIRFLAGAICLLLVLNFVGFRSDGGSATSLSKLSIRRVHKYAHIYGNASSDGAGGSEASRLPASPLALSKDRERDQELNGGPNSTIRTVIATANFTSIPQDLTRFLLGTKKFLPPRQKSTSALLANCTDPDPRDGGPITPNTTLESLDVIEAELGPLLRPGGAFEPENCNAQHHVAIVVPFRDRYAHLLLFLRNIHPFLMKQRIAYRIFIVEQTNGKPFNRAAMMNIGYLEALKLYQWDCFIFHDVDLLPLDDRNLYNC-PRQPRHMSVAIDTLNFRLPYRSIFGGVSAMTREHFQAVNGFSNSFFGWGGEDDDMSNR-----LKHANLFISRYPVNIARYKMLKHQKEKAN---PKRYENLQNGMSKIEQDGINSIKYSIYSIKQFPTFTWYLAELKNSERKS----------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * . * *:: * . : : :*: .: : . . : :. .: :*: * * *. .* **:: : . * .* : ** :.* .*:.: :.**:**.* * ** :* ::**** :*:: * *:::.*:.. .**** ::*:* *.*: :*.*:::******* :*:* * * *: * *::**::.: : *** . ******:* ::: :***.*.::********:: * :: :.: * * * :.:***:**: ::.* *:*:: * . . .**:**:.* : : : * :* .:: . : . ", "identical_positions": 104, "similar_positions": 116, "identity": "22.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110627-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0KZK4-1", "uniprot_id": "A0ABK0KZK4_RAT", "id": "A0ABK0KZK4-1", "name": "", "aln": "MKDTGHREHNRTQPHTSHAHPWTWTAQSPAPSRGPPSSQWKPQALLVVSQLTGGKMGAVTARRCVEWLLGLYFVSHIPITMFIDLQALLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLFCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAVHTIT----TLIPILYTILFEDFSKAIAFKGQRPENFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKFE-------EKRKKK-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VD00-1", "uniprot_id": "SGMR2_MOUSE", "id": "Q8VD00-1", "name": "Sigma intracellular receptor 2", "aln": "-------------------------------------------------------MGALAARRCVEWLLGLYFVSHIPITLFIDLQAVLPPELYPQEFSNLLRWYSKEFKDPLMQEPPVWFKSFLLCELVFQLPFFPIAAYAFFKGSCRWIRIPAIIYAAHTIT----TLIPILYTLLFEDFSKAVAFKGQRPESFRERLTLVGVYAPYLIIPLILLLFMLRNPYYKYE-------EKRKKK-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5BJF2-1", "uniprot_id": "SGMR2_HUMAN", "id": "Q5BJF2-1", "name": "Sigma intracellular receptor 2", "aln": "-------------------------------------------------------MGAPATRRCVEWLLGLYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMT----TLIPILSTFLFEDFSKASGFKGQRPETLHERLTLVSVYAPYLLIPFILLIFMLRSPYYKYE-------EKRKKK-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P2L7-1", "uniprot_id": "A0A8M1P2L7_DANRE", "id": "A0A8M1P2L7-1", "name": "Transmembrane protein 97", "aln": "-----------------------------------------------------------MFLRVLEIIYFIYFASHIPITLLVDLQALLPEHVYPPELIKLLHWYAGEFKDPMMMDPPAWFKSFVFCEALVQLPFFPVAAYAFLKGGCKWIRTPAIIYSVHVAT----TLVPILSHILFHKFP-LSPHPG--PQTLNERLTLVSIYAPYLIIPIMILLTMLFSATYNSPSLKGNAPSKAKKQR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q12155-1", "uniprot_id": "EMA19_YEAST", "id": "Q12155-1", "name": "Efficient mitochondria targeting-associated protein 19", "aln": "----------------------------------------------------------MKLGHREQQFYLWYFIVHIPITIFIDSSVVIPAKWQLGIAQKVVSDHIAKQHDFLLSEKPEWLYWFVVLELVLQLPLFVYFVNKFWNSSELQVNTNSRLKKWLRIYGWNASLTTLICIVVIFKRGYIPYDVLKTSLSMTQKCQLASVYLPTFLIPLRLCFV------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : ** *****:::* ..::* . ::: : : :* :: : * *: *:. * :.***:* . * :.. :. : : :* .:: .:: . . .: :: *..:* * ::**: : : ", "identical_positions": 25, "similar_positions": 55, "identity": "10.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110627-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7EUG0-1", "uniprot_id": "F7EUG0_RAT", "id": "F7EUG0-1", "name": "", "aln": "MRPYVQKRKKTQEQPGGAFVCLLLRGFCGIMAAQTDLWDAIVIGAGVQGCFTAYHLAQNSKKVLLLEQFLLPHSRGSSHGQSRIIRKAYPEDFYTRMMDECYRTWAQLEREAGAQLHRRTELLFLGMKENPGLKTIQATLSRQGIDHECLSSVHLKQRFPNIRFTKGEVGLLDKTGGVLYADKALRALQHVIRQLGGMVCDGEKVVEIRPGLPVTVKTTLKSYQANSLVITAGPWTNRILRPLGIELPLQTLRINVCYWREKVPGSYSVSQAFPCILSLDLAP--HHIYGLPASEYPGLMKVCYHHGDSVDPEERDCPKTFSDIQDVQILCHFVKDHLPGLRPEPDIMERCMYTNTPDEHFILDCHPKYDNIVIGAGFSGHGFKLAPAVGKVLYELSMKLPPSYDLAPFRISRFSKLSKAHL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D826-1", "uniprot_id": "SOX_MOUSE", "id": "Q9D826-1", "name": "Peroxisomal sarcosine oxidase", "aln": "------------------------------MAAQTDFWDAIVIGAGIQGCFTAYHLAKHSKSVLLLEQFFLPHSRGSSHGQSRIIRKAYPEDFYTMMMKECYQTWAQLEREAGTQLHRQTELLLLGTKENPGLKTIQATLSRQGIDHEYLSSVDLKQRFPNIRFTRGEVGLLDKTGGVLYADKALRALQHIICQLGGTVCDGEKVVEIRPGLPVTVKTTLKSYQANSLVITAGPWTNRLLHPLGIELPLQTLRINVCYWREKVPGSYGVSQAFPCILGLDLAP--HHIYGLPASEYPGLMKICYHHGDNVDPEERDCPKTFSDIQDVQILCHFVRDHLPGLRAEPDIMERCMYTNTPDEHFILDCHPKYDNIVIGAGFSGHGFKLAPVVGKILYELSMKLPPSYDLAPFRMSRFSTLSKAHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P0Z9-1", "uniprot_id": "SOX_HUMAN", "id": "Q9P0Z9-1", "name": "Peroxisomal sarcosine oxidase", "aln": "------------------------------MAAQKDLWDAIVIGAGIQGCFTAYHLAKHRKRILLLEQFFLPHSRGSSHGQSRIIRKAYLEDFYTRMMHECYQIWAQLEHEAGTQLHRQTGLLLLGMKENQELKTIQANLSRQRVEHQCLSSEELKQRFPNIRLPRGEVGLLDNSGGVIYAYKALRALQDAIRQLGGIVRDGEKVVEINPGLLVTVKTTSRSYQAKSLVITAGPWTNQLLRPLGIEMPLQTLRINVCYWREMVPGSYGVSQAFPCFLWLGLCP--HHIYGLPTGEYPGLMKVSYHHGNHADPEERDCPTARTDIGDVQILSSFVRDHLPDLKPEPAVIESCMYTNTPDEQFILDRHPKYDNIVIGAGFSGHGFKLAPVVGKILYELSMKLTPSYDLAPFRISRFPSLGKAHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P8J4-1", "uniprot_id": "A0A8M1P8J4_DANRE", "id": "A0A8M1P8J4-1", "name": "Peroxisomal sarcosine oxidase", "aln": "--------------------------------MSSKVFDCIVIGAGIQGSCTAYQLAKNKQKTLLLEQFVLPHSRGSSHGQTRIIRKAYEEDFYTQMMQESYELWAELEKEAGVELYRRTGLLVMGPEKSEGFSKLKDTMQRHKIPTVFLEKQEFNEHISNVNLSEGNGALIDTFAGVLYAERSLQAVQRLFQCSGGVLKDGQTVTGVSPGAVVTVSTGSAVYRGKSVVITAGPWANTLLAHAGLQLPLKVVKINVCYWKEKIPGTYSVDQSFPCFIQMEPKEGEYDIYGLPSNEYPGLMKVCYHMGSETDPDERD---KQTDRGDIDILARYVTRCLPGLVPAPAVVESCMYTVTPDHHFVLDSHPSYGNIIIGAGFSGHGFKFSPIIGKVLSQLAMGQVPSHDLSPFRIQRFQSQSKSSL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ....:*.******:**. ***:**:: : ******.***********:******* ***** **.*.*. **:**:***.:*:*:* **.:* ::. :..:: .:.*: : *.. .:::::.*:.:..*: .*:*. .**:** ::*:*:* : ** : **:.*. : ** ***.* *:.:*:*******:* :* *:::**:.::******:* :**:*.*.*:***:: : :.*****:.*******:.** *. .**:*** :* *::**. :* **.* . * ::* **** ***.:*:** **.*.**:***********::* :**:* :*:* **:**:***:.** . .*: *", "identical_positions": 186, "similar_positions": 128, "identity": "44.08%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110628-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63912-1", "uniprot_id": "OMGP_MOUSE", "id": "Q63912-1", "name": "Oligodendrocyte-myelin glycoprotein", "aln": "----MEYQILKMSSCLFILLFLTPGILCICPLQCTCTERHRHVDCSGRNLTTLPPGLQENIIHLNLSYNHFTDLHNQLTPYTNLRTLDISNNRLESLPAQLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPEQSFDQLLQLQEITLHNNRWSCDHKQNITYLLKWVMETKAHVIGTPCSKQVSSLKEQSMYPTPPGFTSSLFTMSEMQTVDTINSLSMVTQPKVTKTPKQYRGKETTFGVTLSKDTTFSSTDRAVVAYPEDTPTEMTNSHEAAAATLTIHLQDGMSSNASLTSATKSPPSPVTLSIARGMPNNFSEMPRQSTTLNLRREETTANGNTRPPSAASAWKVNASLLLMLNAVVMLAG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23515-1", "uniprot_id": "OMGP_HUMAN", "id": "P23515-1", "name": "Oligodendrocyte-myelin glycoprotein", "aln": "----MEYQILKMSLCLFILLFLTPGILCICPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWSCDHKQNITYLLKWMMETKAHVIGTPCSTQISSLKEHNMYPTPSGFTSSLFTVSGMQTVDTINSLSVVTQPKVTKIPKQYRTKETTFGATLSKDTTFTSTDKAFVPYPEDTSTETINSHEAAAATLTIHLQDGMVTNTSLTSSTKSSPTPMTLSITSGMPNNFSEMPQQSTTLNLWREETTTNVKTPLPSVANAWKVNASFLLLLNVVVMLAV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FDN5-1", "uniprot_id": "E7FDN5_DANRE", "id": "E7FDN5-1", "name": "", "aln": "MKRKAQIAPASMPANLLLLLLFGVRVLAICPPMCTCSRGHRVVDCSARGLAILPESLQHNIHFLNLSYNRIQNLDGLLKHFDHLRTLDISYNHLHHLPVGLPRALWDIRASGNYIRQLEKNDTAYHWNLQNLDLSFNLLERAVLINNTLSNLQSLNLSHNKFWTVPTNMPYNLEMVDLSHNYLLQILPGSLDRLPRLKRFYLHANRFTSLSKDIFNQLDDLQLLTLGDNPWACEDEENINHLLTWMQKTPAKVLGCPCYTRPTCGEVH--LATRRTWHSAAFTEQPLG-ADARHPGHRVPLHAVTSG---YLSKSAQLNVALNANAMNTS----------------------EAGEQVLILGGGFRTSTPHSLSTQSSTTIRTRSTKKAHPG-----KAQSTSHQIHKRSFETTIWS----------------LLCTVVILRAL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .*. *::**:: :*.*** * *:. ** ****.*.*: ** .**.** .******:: :*.. *. : :******* *:*. **. ***:**:: *:.* *: *:*.****:***: **:* *:**:.***:*** .*: **** **:******** :*.:****:* * *****:* .*..*.::*** *:** :..: *:** :** :** :* *:*:.::**.:**.*: :* *:*:* ** .: :. : : .* : *: ** . : .*: :. *. **. * *.: :..:*. :: :* *. .: * .*: :.:. : :*:*..: * * . *. ***: :: :.. :. : *: ..*:: * ", "identical_positions": 155, "similar_positions": 136, "identity": "34.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110628-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96QT6-1", "uniprot_id": "PHF12_HUMAN", "id": "Q96QT6-1", "name": "PHD finger protein 12", "aln": "MWEKMETKTIVYDLDTSGGLMEQIQALLAPPKTDEAEKRSRKPEKEPRRSGRATNHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGEWMCHRCTVRRKKREQKKELGHVNGLVD-KSGKRTTSPSSDTDL-------LDRSASKTELKAIAHARILERRAS-RPGTPTSSASTETPT-SEQNDVDEDIIDVDEEPVAAEPDYVQPQLRRPFELLIAAAMERNPTQFQLPNELTCTTALPGSSKRRRKEETTGKNVKKTQHELDHNGLVPLPVKVCFTCNRSCRVAPLIQCDYCPLLFHMDCLEPPLTAMPLGRWMCPNHIEHVVLNQKNMTLSNRCQVFDRFQDTVSQHVVKVDFLNRIHKKHPPNRRVLQSVKRRSLKVPDAIKSQYQFPPPLIAPAAIRDGELICNGIPEESQMHLLNSEHLATQAEQQEWLCSVVALQCSILKHLSAKQMPSHWDSEQTEKADIKPVIVTDSSVTTSLQTADKTPTPSHYPLSCPSGISTQNSLSCSPPHQSPALEDIGCSSCAEKSKKTPCGTANGPVNTEVKANGPHLYSSPTDSTDPRRLPGANTPLPGLSHRQGWPRPLTPPAAGGLQNHTVGIIVKTENATGPSSCPQRSLVPVPSLPPSIPSSCASIENTSTLQRKTVQSQIGPPLTDSRPLGSPPNATRVLTPPQAAGDGILATTANQRFSSPAPSSDGKVSPGTLSIGSALTVPSFPANSTAMVDLTNSLRAFMDVNGEIEINMLDEKLIKFLALQRIHQLFPSRVQPSPGSVGTHQLASG-----GHHIEVQRKEVQARAVFYPLLGLGGAVNMCYRTLYIGTGADMDVCLTNYGHCNYVSGKHACIFYDENTKHYELLNYSEHGTTVDNVLYSCDFSEKTPPTPPSSIVAKVQSVIRRRRHQKQDEEPSEE------AAMMSSQAQGPQRRPCNCKASSSSLIGGSGAGWEGTALLHHGSYIKLGCLQFVFSITEFATKQPK-GDAS---LLQDGVLAEKLSLKPHQGPVLRSNSVP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5SPL2-1", "uniprot_id": "PHF12_MOUSE", "id": "Q5SPL2-1", "name": "PHD finger protein 12", "aln": "MWEKMETKTIVYDLDTSGGLMEQIQALLAPPKTDEAEKRSRKPEKESRRSGRATNHDSCDSCKEGGDLLCCDHCPAAFHLQCCNPPLSEEMLPPGEWMCHRCTVRRKKREQKKELGHVNGLVD-KSSKRTTSPSSDTDL-------LDRPASKTELKAIAHARILERRAS-RPGTPTSNASTETPT-SEHNDVDEDIVDVDEEPVAAEPDYVQPQLRRPFELLIAAAMERNPTQFQLPNELTCTTALPGSSKRRRKEETTGKNVKRTQHELDHNGLVPLPVKVCFTCNRSCRVAPLIQCDYCPLLFHMDCLEPPLTAMPLGRWMCPNHIEHVVLNQKNLTLSNRCQVFDRFQDTISQHVVKVDFLNRIHKKHPPNRRVLQSVKRRSLKVPDAIKSQYQFPPPLIAPAAIRDGELICSGVPEESQTHLLNSEHLATQAEQQEWLCSVVALQCSILKHLSAKQMPSPWDSEQTEKADIKPVIVTDSSITTSLQTADKAPLPSHYPLSCPSAVSTQNSLGCSPPHQPPTLEDISCSSCVEKSKKAPCGTANGPVNTEIKANGPHLYSSPTDSTDPRRLPGANTPLPGLTHRQGWPRPLTPPSAGGLQNH-VGIIVKTENATGPSSCPQRSLVPVPSLPPSIPSSCASIENTSTLHRKTVQSQIGPSSTESRPLGSPPNATRVLTPPQAAGDSILATGANQRFCSPAPSSDGKVSPGTLSIGSALTVPSFPANSTAMVDLTNSLRAFMDVNGEIEINMLDEKLIKFLALQRVHQLFPSRVQASPGNVGTHPLASG-----GHHPEVQRKEVQARAVFCPLLGLGGAVNMCYRTLYIGTGADMDVCLTNYGHCNYVSGKHACIFYDENTKHYELLNYSEHGTTVDNVLYSCDFSEKTPPTPPSSIVAKVQSVIRRRRHQKQDEEPSEE------AAMMSSQAQGPQRRPCNCKASSSSLIGGSGAGWEGTALLHHGSYIKLGCLQFVFSITEFATKQPK-GDAS---LLQDGVLAEKLSLKPHQGPVLRSNSVP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2R8RZL6-1", "uniprot_id": "A0A2R8RZL6_DANRE", "id": "A0A2R8RZL6-1", "name": "PHD finger protein 12", "aln": "MWDKMETPKILYDLDTSGGLMEQIQQLLAPPRSEDGEKR-RKPERETRRGGRATNHDTCDSCREGGDLLCCDHCPAAFHLQCCNPPLSREMLPPGDWMCHRCSVRKKKREQKAEQ--VNGALERQLSKRSSSPAAELELGTLRLDGLPSAASGGLRLAVAQVRLLERRTSSRPGTPTSNASTDTPTPSEHNDVDEDLMDVEEDVQGSESENATPRLKKPFQMLIAAAMERNPTQFQLPSELTCTTSLPGSSKRRRKEEAIGKNMKRPQHELDPSGLVPLPVKVCFTCGKSCRVAPLIQCDYCALLFHMDCLDPPLTAMPTGRWMCPNHVEHMVLNQKNVTLSTRCQVFDHFQDRLSQHAVKVDFLRWVHRQHHPNRRGVRHIKKKTLKVPNAIKSHYQNPPLLMDQVGLRNGELVPNGFMEQECS--SSTQHLTSEEEQEEWLRHVIALQCSIMKHLSAKQMSSSLR--DSEQADLS-----DAKTQECMEMQELSSQDSDYLQSRSTKVGPQGAQVLS------TIVPKHPESCNEQSSQ---GEADSPTEKGTGVNGPVACEGDTCTTAETSHKPSSP-----SRRQ--------NLESALPNH---VDIKTESSSPFSSCMQR-----DSPSTSLLSGSPARHHGSTLGNS-------------------------------------SSGLNSSLSS--QTKENKVSPDLMSAGKGSTLP------SSIGSLYSYIKNVVQGDTEVDMNKLDEELIRLLAWQRIQQLLSPKSLQASSKCGTPPAATASLSKPSLHADAQKRDVQARAVLCPLTGKGAAINMCYRTLYIGTGAEMDVCLTNYGHCNYVSGKHACIFYDENTKHYELLNYSEHGTTVDNVLYSCDFSDKPNITSPSALASKVQNSIRGNKSRRPIGEVSTEPVPVPTDSMMSSLAQGGPKNPCNCKASSSSLIGGSGAGWEGTALLHHSSCIKVGCLQFLFSIAEFASSQPKKEDASSTVSQEETQVVDVQTHKLHQMPVLQSKSVS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:**** .*:************** *****::::.*** ****:*.**.*******:****:*************************.******:******:**:****** * *** :: : .**::**::: :* * .** *:*:.*:****:* *******.***:*** **:******::**:*: .:*.: . *:*::**::****************.******:************: ***:*:.***** .*************.:*************.********:******* ********:**:******:***.******:*** :***.******. :*::* **** :: :*:::****:****:** ** *: ..:*:***: .*. *:. .::**::: **:*** *:******:********.* ::*:**:. *:. .:: : :. *.* * .: :..*.: * :: .** *:*.: * *:.*.:. .*** .. * :* :.. ::** ..* ** : :***.:: *** ** * ..*: *...: .: *** .. :: *. :.* :.:.****. :* *.. *:* ::: .* . :: .:: : *:::* ***:**::** **::**:..: :... ** *:. . * :.*:::******: ** * *.*:*************:****************************************************:*. *.**::.:***. ** .: :: * * * :**** *** :.***************************.* **:*****:***:***:.*** *** :: :.: : * ** ***:*:**.", "identical_positions": 531, "similar_positions": 242, "identity": "51.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110628-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MA42-1", "uniprot_id": "F1MA42_RAT", "id": "F1MA42-1", "name": "", "aln": "------MRPAALLLLPSLLALLAHGLSSEAPITGEGQAT---GIREMDGELTAAPTPEQSDRGVHFVTTAPTLKLLNHHPLLEEF-------LQEGLEGREEAPRPALPFQPDSPTPFTPSPLPRLT-NQDNRPVFTSPTPAVAAAPTQPHSRKKPWNPESEPPELYITSPLPPGPSMAVPTLHPED---RPSTTPPSQAWTPTQ-EGPGDMGRPWVPEIMSKTTGLGIEGTIATSTASGDDEE--TTTTTIITTVTT-IQPPGPCSWNFSGPEGSLDSPAVPSVPSDVGLDCLYYISVYPGYGVEIKVKNISLQEGETITVEGLGGPDPLPLANQSFLLRGQVIRSPTHQAAVRFQSLPLPAGPGTFHFHYQAYLLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARFLTCLNATQPFWDSQEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPESQRLHLHFEKVSLAEDDDRLIIRNGNNVEAPPVYDSYEVEYLPIEGLLSSGRHFFVEFSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSAPSYPVGTTVEFSCDPGYTLEQGSIIIECVDLRDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGSGDVLTFYDGDDLTARVLGQYSGPRGHFKLFTSMADVTIQFQSDPGTSALGYQQGFVIHFFEVPRNDTCPELPEIPNGWKNPSQPELVHGTVVTYQCYPGYQVVGSSILMCQWDLSWSEDLPSCQRVTSCHDPGDVEHSRRLISSLKFPVGATVQYICDQGFVLTGSAILTCHDRQAGSPKWSDRAPKCLLEQFKPCHGLSAPENGARSPEKRLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLDGFYNGRSLDVAKAPATSSALDAAHMAAAIFLPLVAMVLLVGGVYLYFSRLQGKSPLQLPGTHPRPYNRITVESAFDNPTYETG-----------VSIHVGLDTSSGLVL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TSK2-1", "uniprot_id": "SEZ6_MOUSE", "id": "Q7TSK2-1", "name": "Seizure protein 6", "aln": "------MRPAALLLLPSLLALLAHGLSSEAPITGEGHAT---GIRETDGELTAAPTPEQSDRGVHFVTTAPTLKLLNHHPLLEEF-------LQEGLE-REEAPQPALPFQPDSPTHFTPSPLPRLT-NQDNRPVFTSPTPAVAAAPTQPHSREKPWNLESKPPELSITSSLPPGPSMAVPTLLPED---RPSTTPPSQAWTPTQ-EGPGDMDRPWVPEVMSKTTGLGVEGTIATSTASGDDEE--TTTTIITTTVTT-VQPPGPCSWNFSGPEGSLDSPTAPSSPSDVGLDCFYYISVYPGYGVEIKVENISLQEGETITVEGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPLPAGPGTFHFRYQAYLLSCHFPRRPAYGDVTVTSLHPGGSAHFHCATGYQLKGARFLTCLNATQPFWDSQEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPESQRLHLHFEKVSLAEDDDRLIIRNGNNVEAPPVYDSYEVEYLPIEGLLSSGRHFFVEFSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSAPSYPVGTTVEFSCDPGYTLEQGSIIIECVDLHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGSGDVLTFYDGDDLTARVLGQYSGPRGHFKLFTSMADVTIQFQSDPGTSALGYQQGFVIHFFEVPRNDTCPELPEIPNGWKNPSQPELVHGTVVTYQCYPGYQVVGSSILMCQWDLSWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYVCDQGFVLTGSAILTCHDRQAGSPKWSDRAPKCLLEQFKPCHGLSAPENGARSPEKRLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLDGFYNGRSLDVAKAPAASSALDAAHLAAAIFLPLVAMVLLVGGVYLYFSRFQGKSPLQLPRTHPRPYNRITVESAFDNPTYETG-----------SLSFAGDERI-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53EL9-1", "uniprot_id": "SEZ6_HUMAN", "id": "Q53EL9-1", "name": "Seizure protein 6 homolog", "aln": "------MRPVALLLLPSLLALLAHGLSLEAPTVGKGQAP---GIEETDGELTAAPTPEQPERGVHFVTTAPTLKLLNHHPLLEEF-------LQEGLEKGDEELRPALPFQPDPPAPFTPSPLPRLA-NQDSRPVFTSPTPAMAAVPTQPQSKEGPWSPESESPMLRITAPLPPGPSMAVPTLGPGE---IASTTPPSRAWTPTQ-EGPGDMGRPWVAEVVSQGAGIGIQGTITSSTASGDDEETTTTTTIITTTITT-VQTPGPCSWNFSGPEGSLDSPTDLSSPTDVGLDCFFYISVYPGYGVEIKVQNISLREGETVTVEGLGGPDPLPLANQSFLLRGQVIRSPTHQAALRFQSLPPPAGPGTFHFHYQAYLLSCHFPRRPAYGDVTVTSLHPGGSARFHCATGYQLKGARHLTCLNATQPFWDSKEPVCIAACGGVIRNATTGRIVSPGFPGNYSNNLTCHWLLEAPEGQRLHLHFEKVSLAEDDDRLIIRNGDNVEAPPVYDSYEVEYLPIEGLLSSGKHFFVELSTDSSGAAAGMALRYEAFQQGHCYEPFVKYGNFSSSTPTYPVGTTVEFSCDPGYTLEQGSIIIECVDPHDPQWNETEPACRAVCSGEITDSAGVVLSPNWPEPYGRGQDCIWGVHVEEDKRIMLDIRVLRIGPGDVLTFYDGDDLTARVLGQYSGPRSHFKLFTSMADVTIQFQSDPGTSVLGYQQGFVIHFFEVPRNDTCPELPEIPNGWKSPSQPELVHGTVVTYQCYPGYQVVGSSVLMCQWDLTWSEDLPSCQRVTSCHDPGDVEHSRRLISSPKFPVGATVQYICDQGFVLMGSSILTCHDRQAGSPKWSDRAPKCLLEQLKPCHGLSAPENGARSPEKQLHPAGATIHFSCAPGYVLKGQASIKCVPGHPSHWSDPPPICRAASLDGFYNSRSLDVAKAPAASSTLDAAHIAAAIFLPLVAMVLLVGGVYFYFSRLQGKSSLQLPRPRPRPYNRITIESAFDNPTYETG-----------SLSFAGDERI-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HCZ0-1", "uniprot_id": "A0AC58HCZ0_DANRE", "id": "A0AC58HCZ0-1", "name": "", "aln": "MNSTRNYKPSMVVLILVVFAGIGMARGQGSLTDGRLAVTQRGGQLEAEDGSNPYHTTQDTDRELPLFTTAPPYSGLDHHPPFKPYPPYDPRGQSHGQYFQDSGGAAHHPTMPSSSSHLLQDPSTQLVPHEEALPFSDVAAPRSTTMAPSAAALTQPHVPKIQHKLSVETQRRSSDPSISLSTTDAHTSALPVSKHLDREDFTQTFNIKPQDVTVERKPSVEHDESPESDVDVKASSSVAGDLDDETTTSTIITTTVITNMQTPAPCSANFTSPGGYIETPQQARSWYNANVDCTYTVTVYMGYGVEIQVMNVSLSEGDVVIFEDLGNREPSVLANESILLKGLVVRSWSNQISIHFRSRQPQS--SSLLLRYQAFVLSCNFPDRPAYGDVSVSSLHAEGEAYFYCFNGYQIQGPSTLTCRNATIPYWSGKVPRCLVACGGMVKNATLGRIVSPGFPGNYSNNLTCHWVLQAPEGHRLHVHFEKVALAEDDDRFLIKNGNHIDSPIVYDSYEVEYLPNEGVASSSRHLFVEFTTDGFGTNTGMAIRYEAFAAGHCYEPFVKYGNFTTTDSTYAVGTVVEFTCDPGYTLEQGSVIIECMDPSNPQWNETEPTCRAVCSGEITDSAGMVLSPNWPEAYDKGQDCIWGIHVEEDKRIMLDIQVLHMGKNDLLTFYDGDDLTAKILGQYSGSRPRFKLYTSMADVTIQFQSDPATNIYGYNNGFVVHFFEVPRNDTCPELPEISNGWKTTSHPDLVHGTVVTYQCYPGFEVVGTEMLMCQWDLTWSGDLPSCERVLSCPDPGTVEHSRRVMSGPRLIVGSTVQYICNKGYSLSGNSLLSCYHRDSTGPKWSEKLPKCIPDSFEPCRNPGTPAYTIQSSEKHVYQAGETVRFSCMNGYELQGEPVLRCVPGHPSKWSHPPPLCKAVTLE-YIDERRLDVASADFS---MEGASVAVSIFIPVAVIIIIILSIYFYFSRVQGKS-LRMSMSTSPQYDHIRGESAFENPIYETTRPMIQSSHQRFSLGFCCKERACKES-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* ::*: ::* :. . . : *. .. * * :. .. *.::.:* : :.****. . *:*** :: : ..* :. . * *...: : .* .:*. ::: *. .:* :: .... : * : : * ...**:::.* . *. . :* * * *: ..: . : . .. ::*:.:** :: **:* * **: * :*.*.*** **:.* * :::* :..:** : ::** ******:* *:** **:.: .*.**. :* ***:*:**:* *:** ::* :::*:* : .:: ::***::***:** *******:*:***. *.* *:* .***::*. *** *** *:*..: * *:.****:::*** ********************:*:***.:***:*****:*******::*:**:::::* *********** **: **.:*:***::**. *: :***:***** *************::: .:*.***.***:***********:****:* :********:**************:********.*.:*******:************:**::* .*:***********::******.* :***:**************.*. **::***:*****************.****..*:*:**************::***:.:*******:** *****:** ** *** ******::*. :: **:****:*::*: * *.::*:*:.*:: .****:: ***: :.::**:. .:* :*.**::: ** *::*** ** *:*:. ::*******:**.***:*:*.:*: : : * ****.* : ::.* :*.:**:*:..::::: .:*:****.**** *::. . . *::* ****:** *** . : ", "identical_positions": 485, "similar_positions": 301, "identity": "47.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110714-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60294-1", "uniprot_id": "TYW4_HUMAN", "id": "O60294-1", "name": "tRNA wybutosine-synthesizing protein 4", "aln": "------------------------------------------------MGPRSRERRAG---AVQNTNDSSALSKRSLAARGYVQDPFAALLVPGAARRAPLIHRGYYVRARAVRHCVRAFLEQIGAPQAALRAQILSLGAGFDSLYFRLKTAGRLARAAVWEVDFPDVARRKAERIGETPELCALTGPFE--RGEPASALCFESADYCILGLDLRQLQRVEEALGAAGLDAASPTLLLAEAVLTYLEPESAAALIAWAAQRFPNALFVVYEQMRPQDAFGQFMLQHFRQLNSPLHGLERFPDVEAQRRRFLQAGWTACGAVDMNEFYHCFLPAEERRRVENIEPFDEFEEWHLKCAHYFILAASRG-DTLSHTLVFPSSEAFPRVNPASPSGVFPASVVSSEGQVPNLKRYGHASVFLSPDVILSAGGFGEQEGRHCRVSQFHLLSRDCDSEWKGSQIGSCGTGVQWDGRLYHTMTRLSESRVLVLGGRLSPVSPALGVLQLHFFKSEDNNTEDLKVTITKAGRKDDSTLCCWRHSTTEVSCQNQEYLFVYGGRSVVEPVLSDWHFLHVGTMAWVRIPVEGEVPEARHSHSACTWQGGALIAGGLGASEEPLNSVLFLRPISCGFLWESVDIQPPITPRYSHTAHVLNGKLLLVGGIWIHSSSFPGVTVINLTTGLSSEYQIDTTYVPWPLMLHNHTSILLPEE-QQLLLLGGGGNCFSFGTYFNPHTVTLDLSSLSAGQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GCS5-1", "uniprot_id": "A0AC58GCS5_DANRE", "id": "A0AC58GCS5-1", "name": "tRNA wybutosine-synthesizing protein 4", "aln": "MLCTIKIPLIVFGTILRYKYRHSAYERKPLPLCCFLVVHSEDYTCVQRVMPVNRKREQGKDAAVQGTNDSSVVSKVSAAAQGYFHDDFLKHFVCKMSRRAPLINRGYYVRWKAVDHCVKQFLH---ATKSCSRRQILSLGAGFDSLFFRLRAEGALGGVTVFEVDFPEVARRKAALINSNACLKDLLPDWETVLNKQTNAVFISSGHYNLIGADVRKEQEVEASLSAAGLQWDNPTLILSEVVLTYMETQWSDAVIGWAARLLPQSMFVMYEQIHPDDPFGRVMQSHFLKLNSKIHSLQQYPDNVAQTQRFIQEGWEKCHCLDMNQFYFDLLPEDERQRIENLEPFDEFEEWHQKCSHYFILTASKGSVTRQALLTLPNTSSIPQMTPQWN--THPPLVVQPMCGSPSVEALGMASALLTPEIILLTGGFG-RNGRDT--AARVLIKEKCG--WKSACVEVHGDKVVS---LYQTLTSVPGGGVVLFGGRSSPLSPSGSVVLVTADLADEVQLSFTNIVCTGTGPKPR-----WRHTSTLICYNDKTFLFVFGGRSEKDPILGDAHFLCLEDKHWTEITVVGAGPEARHSHSACPYGGGLVIFGGLGEGGKPLGDALYLRPTSSGFCWEMKDLHPPPVPRYSHSAHVINEKLVVVGGVWLQADGVPGVSIVNLNTGSCVEIQLDTLSVPWPLMLHSFCSELLDCEGSELVLIGGGGNCFSFGTHLNLHPVTVDLKPILCF-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * .*:*. * ***.*****.:** * **:**.:* * :* :******:****** :** ***: **. *.::. * ************:***:: * *. .:*:*****:****** *.... * * :* .: :.*: :.*..* ::* *:*: *.** :*.****: .***:*:*.****:*.: : *:*.***: :*:::**:***::*:*.**:.* .** :*** :*.*:::** ** :**:* ** * .:***:**. :** :**:*:**:********** **:*****:**:* * . *.:*.:.::*::.* ..*. **.. *.:: * **.:*:*::** :**** ::**. : *:...*. **.: : * * **:*:* :. . *:::*** **:**: .*: : ::: : . ::. * :* * ***::* :. ::: :***:**** :*:*.* *** : *..*.* * **********.: ** :* **** . :**...*:*** *.** ** *::** .*****:***:* **::***:*:::...***:::**.** . * *:** ********.. * ** * .:*:*:***********::* *.**:**..: . ", "identical_positions": 318, "similar_positions": 212, "identity": "42.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110715-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "G3V7P1-1", "uniprot_id": "STX12_RAT", "id": "G3V7P1-1", "name": "Syntaxin-12", "aln": "------------------------------MSYGPLDMYRNPGPSGPQPRDFNSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQEN-LQQFQH--STNQLAKETNELLKELGS----LPLPLSASEQRQQKLQKERLMNDFSSALNNFQVVQRKVSEKEKESIARARAGSRLSAEDRQREEQLVSFDSHEEWNQMQSQEEEAAITEQD----------LELIKERETAIQQLEADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERASDQLQRAAYYQKKSRKKMCILVLVLSVIVTVLVVVIWVASK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER00-1", "uniprot_id": "STX12_MOUSE", "id": "Q9ER00-1", "name": "Syntaxin-12", "aln": "------------------------------MSYGPLDMYRNPGPSGPQPRDFNSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQEN-LQQLQH--STNQLAKETNELLKELGS----LPLPLSASEQRQQKLQKERLMNDFSSALNNFQVVQRKVSEKEKESIARARAGSRLSAEDRQREEQLVSFDSHEEWNQMQSQEEEAAITEQD----------LELIKERETAIRQLEADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATDQLQRAAYYQKKSRKKMCILVLVLSVIVTVLVVVIWVASK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86Y82-1", "uniprot_id": "STX12_HUMAN", "id": "Q86Y82-1", "name": "Syntaxin-12", "aln": "------------------------------MSYGPLDMYRNPGPSGPQLRDFSSIIQTCSGNIQRISQATAQIKNLMSQLGTKQDSSKLQEN-LQQLQH--STNQLAKETNELLKELGS----LPLPLSTSEQRQQRLQKERLMNDFSAALNNFQAVQRRVSEKEKESIARARAGSRLSAEERQREEQLVSFDSHEEWNQMQSQEDEVAITEQD----------LELIKERETAIRQLEADILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATEQLQRAAYYQKKSRKKMCILVLVLSVIILILGLIIWLVYKTK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5F7-1", "uniprot_id": "A0ACD6B5F7_DANRE", "id": "A0ACD6B5F7-1", "name": "Syntaxin-12", "aln": "MIVCFLSIHFDFCERSSASPPHLSITVTVIMSYGMMDSS----HSQSQPRDFNNLTQTCSSNIQKITQNTGQIKSMLFQLGTRPDTPELQDR-LQQVQH--YTNQLAKETNRHLKDLGT----LPQPQSPSEQRQQRIQKDRLMNDFSAALNNFQVVQRRAAERERESVARARAGSRFQVDELNQDEQLVTFEKNEGW-RMQTEEE--PVTEED----------LELIKERETNIRQLESDIMDVNQIFKDLAVMIHDQGDMIDSIEANVESAEVHVERGAEQLQHAAYYQRKSRKRMCILALVLSLVATIFAIIIWQAIR--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P32854-1", "uniprot_id": "PEP12_YEAST", "id": "P32854-1", "name": "Syntaxin PEP12", "aln": "--------------------------MSEDEFFGGDNEAVWNGSRFSDSPEFQTLKEEVAAELFEINGQISTLQQFTATLKSFIDRGDVSAKVVERINK--RSVAKIEEIGGLIKKVNTSVKKMDAIEEASLDKTQIIAREKLVRDVSYSFQEFQGIQRQFTQVMKQVNERAKES--LEASEMANDAALLDEEQRQNSSKSTRIPGSQIVIERDPINNEEFAYQQNLIEQRDQEISNIERGITELNEVFKDLGSVVQQQGVLVDNIEANIYTTSDNTQLASDELRKAMRYQKRTSRWRVYLLIVLLVMLLFIFLIMKL-----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12241-1", "uniprot_id": "VAM3_YEAST", "id": "Q12241-1", "name": "Syntaxin VAM3", "aln": "-----------------------------MSFFDIEAQSSKGNSQQEPQFSTNQKTKELSNLIETFAEQSRVLEKECTKIGSKRDSKELRYKIETELIPNCTSVRDKIESNILIHQNGKLSADFKNLKTKYQSLQQSYNQRKSLFPLKTPISPGTSKERKDIHPRTEAVRQDPESSYISIKVNEQSPLLHNEGQHQLQLQEEQEQQQQGLSQEE------LDFQTIIHQERSQQIGRIHTAVQEVNAIFHQLGSLVKEQGEQVTTIDENISHLHDNMQNANKQLTRADQHQRDRNKCGKVTLIIIIVVCMVVLLAVLS-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. . . : : : : ::. : : * .: . .. : * . ::. .. : . * : : : .. .:. :*: . : : . :. . .. * ..: : : :.: : ::*. * .:. : ::* :*::*. ::::** : .*: *: : : . .:* :* :*: : ::: :: .. : : ", "identical_positions": 17, "similar_positions": 94, "identity": "5.26%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110715-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P08118-1", "uniprot_id": "MSMB_HUMAN", "id": "P08118-1", "name": "Beta-microseminoprotein", "aln": "MNVLLGSVVIFATFVTLCNASCYFIPNEGVPGDSTRKCMDLKG-NKHPINSEWQTDNCETCTCYETEISCCTLVSTPVGYDKDNCQRIFKKEDCKYIVVEKKDPKKTCSVSEWII", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A7F1-1", "uniprot_id": "A0AB13A7F1_DANRE", "id": "A0AB13A7F1-1", "name": "Prostate-associated microseminoprotein", "aln": "-MASLTLVLILCAFVSLSDSYCFLKLQK----EGAKYCEDGDDQTRHELGSTWINSKCLRCICSSTEMECCDTMGRAI-IKTEGCTVKYDYSTCKFDVFHPEDPNIKCEYGAVGK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * *:*:.:**:*.:: *:: :: :.:: * * .. .:* :.* * ..:* * * .**:.** :. .: ..:.* :. . **: *.. :**: .*. . ", "identical_positions": 26, "similar_positions": 48, "identity": "22.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110719-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZU86-1", "uniprot_id": "D3ZU86_RAT", "id": "D3ZU86-1", "name": "", "aln": "----MLFSLNEWLWQETYWLPPNVTWAQLE--DRDGLVFAHPHHVLAALPIALVLVAMRIIFERFVALPLSRWMGVQDPIRRK--IKPNPVLEKYFLRMKQRPVETQMVLLASQCGLTLRQ---------------------------------IQRWFRRRRNQDRPCLSKKFCEASWRFVFYLCSFVGGTSILYH-ESWLWTPALCWENYPHQTLNLALSWWYLLELGFYISLLITLPFDIK--RKDFKEQVAHHFVTVGLIVFSYSVNLLRIGSVVLLLHDCSDYLLEGCKMLNYAHFQRGCDTLFIIFSLVFFYTR-----------LVFFPTEVIYTAVFDSIKNSGPFFGYYFFIVLLGMLQILHVYWFCLILRMICSFLRKGQMREDIRSDVEESDSSDDEAVSEGP-QLKNGMARGSRAAITNGPRSRAAACLTNGHTRAT----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D6J1-1", "uniprot_id": "CERS4_MOUSE", "id": "Q9D6J1-1", "name": "Ceramide synthase 4", "aln": "----MSFSLSEWLWQETYWLPPNVTWAELE--DRDGLVFAHPHHVLAAFPVALVLVAVRIVFERFVALPLSRWMGVQDPIRRK--IKPNPVLEKYFLRMKQCPEETQMVLLASQCGLTLRQ---------------------------------TQRWFRRRRNQDRPSLSKKFCEACWRFVFYLCSFVGGTSILYH-ESWLWSPSLCWENYPHQTLNLSLYWWYLLELGFYLSLLITLPFDVK--RKDFKEQVVHHFVAVGLIGFSYSVNLLRIGAVVLLLHDCSDYLLEGCKILNYAHFRRGCDALFIMFALVFFYTR-----------LIFFPTQVIYTSVYDSIKNSGPFFGYYFFIVLLVMLQILHVYWFCLILRMLYSFLHKGQMTEDIRSDVEEPDSSDDEPVSEGP-QLKNGMARGSRVAVTNGPRSRAAACLTNGHTRAT----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HA82-1", "uniprot_id": "CERS4_HUMAN", "id": "Q9HA82-1", "name": "Ceramide synthase 4", "aln": "----MLSSFNEWFWQDRFWLPPNVTWTELE--DRDGRVYPHPQDLLAALPLALVLLAMRLAFERFIGLPLSRWLGVRDQTRRQ--VKPNATLEKHFLTEGHRPKEPQLSLLAAQCGLTLQQ---------------------------------TQRWFRRRRNQDRPQLTKKFCEASWRFLFYLSSFVGGLSVLYH-ESWLWAPVMCWDRYPNQTLKPSLYWWYLLELGFYLSLLIRLPFDVK--RKDFKEQVIHHFVAVILMTFSYSANLLRIGSLVLLLHDSSDYLLEACKMVNYMQYQQVCDALFLIFSFVFFYTR-----------LVLFPTQILYTTYYESISNRGPFFGYYFFNGLLMLLQLLHVFWSCLILRMLYSFMKKGQMEKDIRSDVEESDSSEEAAAAQEPLQLKNGAAGGPRPAPTDGPRSRVAGRLTNRHTTAT----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BAR8-1", "uniprot_id": "A0A8M2BAR8_DANRE", "id": "A0A8M2BAR8-1", "name": "", "aln": "-----MDALSRWFWKQEFWLPPGIVWEDLE--EMQGSRRPMPRDLLLALPLALAFIMLRYAFERRVAFPLSRVLGVKDPVRLK--VTPSPSLEAFYTKNSRQPTQIEISGLVKQCGLTHRQ---------------------------------VETWFRNRRNLDRPSNTTKFCEACWRFAFYLVAFTAGLLSLIN-TAWFWDQRECWRGFPRQPLQELHYWYYMLELSFYWSLLLCVSVDVK--RKDFKEQIIHHFATIFLLGFSYCSNYIRIGTLVMLVHDASDFLLESAKMFNYAGWKKTCDSLFVIFAAVFLVTR-----------LLVFPSKIIYTTLVLSMEVFEPFLGYYFFNALLLVLQALHIYWAYLILRMVYKFLFLGKLDKDERSDVETEPEEEEEEEKEEE-EEEQRSWRKRKVVLDSRRAMLSSSCVLNNLTQQKADAQRRPKAR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W423-1", "uniprot_id": "Q9W423_DROME", "id": "Q9W423-1", "name": "", "aln": "--MDILNEFSNVFWSTHIWLPPNTTWADIAPGSRPDVVHANYKDLIWPIPFAAVVMLVRYTLERFWISPVGKSLGIRSSRPKK--AANVPILEKTYAKSTRLDKK-KLVPLSKQTDMSERE---------------------------------IERWWRLRRAQDKPSTLVKFCENTWRCIYYLYSFIFGVIVLWD-KPWFWDVKSCWYGYPHQSISNDIWWYYMISMSFYWSLTGTQFFDVK--RKDFWQMFIHHMVTLLLMSLSWVCNLHRVGSLVLVVHDCADIFLEAAKLTKYAKYQKLCDAIFAIFTVVWIVTR-----------LGFYP-RIIYSSSVEAPRILPMFPAYYIFNSLLLMLLVLHVIWTYMILKIVVDSLQKGLMSGDIRS-----SDSEDLTDSSGNARLTNGSARSKNKSISSAPSDKGSAGGAGSRAGARVATTERREE-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38703-1", "uniprot_id": "LAG1_YEAST", "id": "P38703-1", "name": "Ceramide synthase LAG1", "aln": "-MTSATDKSIDRLVVNAKTRRRNSSVGKIDLGDTVPGFAAMPESAASKNEAKKRMKALTGDSKKDSDLLWKVWFSYREMNYRHSWLTPFFILVCVYSAYFLSGNRTESNPLHMFVAISYQVDGTDSYAKGIKDLSFVFFYMIFFTFLREFLMDVVIRPFTVYLNVTSEHRQKRMLEQMYAIFYCGVSGPFGLYIMYHSDLWLFKTKPMYRTYPVITNPFLFKIFYLGQAAFWAQQACVLVLQLEKPRKDYKELVFHHIVTLLLIWSSYVFHFTKMGLAIYITMDVSDFFLSLSKTLNYLN-SVFTPFVFGLFVFFWIYLRHVVNIRILWSVLTEFRHEGNYVLNFATQQ-YKCWISLPIVFVLIAALQLVNLYWLFLILRILYRLIWQG-IQKDERSDSDSDESAE------NEESKEKCE--------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P28496-1", "uniprot_id": "LAC1_YEAST", "id": "P28496-1", "name": "Ceramide synthase LAC1", "aln": "MSTIKPSPSNNNLKVRSRPRRK-SSIGKIDLGDTVPSLGTMFETKESKTAAKRRMQRLSEATKNDSDLVKKIWFSFREISYRHAWIAPLMILIAVYSAYFTSGNTTKTNVLHRFVAVSYQIGDTNAYGKGINDLCFVFYYMIFFTFLREFLMDVVIRPFAIRLHVTSKHRIKRIMEQMYAIFYTGVSGPFGIYCMYHSDLWFFNTKAMYRTYPDFTNPFLFKVFYLGQAAFWAQQACILVLQLEKPRKDHNELTFHHIVTLLLIWSSYVFHFTKMGLPIYITMDVSDFLLSFSKTLNYLD-SGLAFFSFAIFVVAWIYLRHYINLKILWSVLTQFRTEGNYVLNFATQQ-YKCWISLPIVFVLIGALQLVNLYWLFLIFRVLYRILWRG-ILKDDRSDSESDEESDESSTTPTDSTPTKKDI-------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: . . . . : :. :. :. : * : : * :: : : :: * : : : * : . *:: : :* . :*: . .*: . .::: ***. : **:.:: *: *: : ::* : : * :* :*. .* :* * :* :: * * : . * : : . :. *: * ::: * :*:::: : * : * ** . : : ", "identical_positions": 34, "similar_positions": 85, "identity": "7.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110721-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96D31-1", "uniprot_id": "ORAI1_HUMAN", "id": "Q96D31-1", "name": "Calcium release-activated calcium channel protein 1", "aln": "MHPEPAPPPSRSSPELPPSGGSTTSGSRRSRRRSGDGEPPGAP--PPPPSAVTYPDWIGQSYSEVMSLNEHSMQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLDADHDYPPGLLIAFSACTTVLVAVHLFALMISTCILPNIEAVSNVHNLNSVKESPHERMHRHIELAWAFSTVIGTLLFLAEVVLLCWVKFLPLKKQPGQPRPTSKPPASGAAANVS-TSGITPGQAAAIASTTIMVPFGLIFIVFAVHFYRSLVSHKTDRQFQELNELAEFARLQDQLDHRGDHPLTPGSHYA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BWG9-1", "uniprot_id": "ORAI1_MOUSE", "id": "Q8BWG9-1", "name": "Calcium release-activated calcium channel protein 1", "aln": "MHPEPAPPPSHSNPELPVSGGSSTSGSRRSRRRSGDGEPSGAPPLPPPPPAVSYPDWIGQSYSEVMSLNEHSMQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLDTDHDYPPGLLIVFSACTTVLVAVHLFALMISTCILPNIEAVSNVHNLNSVKESPHERMHRHIELAWAFSTVIGTLLFLAEVVLLCWVKFLPLKRQAGQPSPTKPPAESVIVANHSDSSGITPGEAAAIASTAIMVPCGLVFIVFAVHFYRSLVSHKTDRQFQELNELAEFARLQDQLDHRGDHSLTPGTHYA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B7L6-1", "uniprot_id": "A0ACD6B7L6_DANRE", "id": "A0ACD6B7L6-1", "name": "Calcium release-activated calcium channel protein 1", "aln": "-----------------------------------------------------------------MSLNEHSLQALSWRKLYLSRAKLKATSRTSALLSGFAMVAMVECQLEEDHNYPPGLLIAFSACTTVLVAVHLFALMISTCILPNLEAVSNVHNLNSIKESPHERMHRHIELAWAFSTVIGTLLFLAEVVLLCWVKFLPLSQTP----VTQK-------ENVTQAPGISEGKAAAIASTTIMVPFALVFIVFAVHFYRSLVSHKTERQHEELEVLAKITQMQNQLDQRGE---ASSIHFA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *******:*****************:***************** **: **:*******.*************************:***********:******************************************.: . *. * : :.**: *:*******:**** .*:*****************:**.:**: **:::::*:***:**: :.. *:*", "identical_positions": 178, "similar_positions": 35, "identity": "58.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110721-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2A9-1", "uniprot_id": "GGT5_MOUSE", "id": "Q9Z2A9-1", "name": "Glutathione hydrolase 5 proenzyme", "aln": "MAWGHRATVCLVLLGVGLGLVIVVLAAVLSPRQASCGPGAFTRAAVAADSKICSDIGRAILQQRGSPVDAAIAALVCTGVVNPQSMGLGGGVVFTIYNASTGKVEIINARETVPASYDQGLLNQCKNVLPLGTGAQWIGVPGELRGYAEAHRRHGRLPWAQLFQPTIALLREGFRVPFILSQFLNNSILRPHLSAST-LRQLFFNG--TETLRSQDPFPWPALANTLETVAKEGAEVLYTGRLGRMLVEDIAKQGSLLTVQDLAAFQPEVVEPLEMPLGNYTLYSPPPPAGGAILSFILNVLKGFNFSAETVARPGGEVNMYHHLVETLKFAVGQRWRLWDPSSHPGIQNISRDLLREDLAQRIRQQIDGRGDHHQLSHYNLTGVRGNRMGTSHVSVLGEDGSAVAATSTINTPFGAMVYSPRTGILLNNELLDLCWRHMPTSPITP----------------PPVPGERPPSSMVPSILVNKGQGSKLVIGGAGGELIISAVAQTIMNKLWLGFDLTEAIASPILHVNSKGHVEYEPKFNQEVQKGLQDRGQIQSQSQRPVFLNAVQAVFQEGPCVYAASDLRKAGKASGY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P36269-1", "uniprot_id": "GGT5_HUMAN", "id": "P36269-1", "name": "Glutathione hydrolase 5 proenzyme", "aln": "MARGYGATVSLVLLGLGLALAVIVLAVVLSRHQAPCGPQAFAHAAVAADSKVCSDIGRAILQQQGSPVDATIAALVCTSVVNPQSMGLGGGVIFTIYNVTTGKVEVINARETVPASHAPSLLDQCAQALPLGTGAQWIGVPGELRGYAEAHRRHGRLPWAQLFQPTIALLRGGHVVAPVLSRFLHNSILRPSLQAST-LRQLFFNG--TEPLRPQDPLPWPALATTLETVATEGVEVFYTGRLGQMLVEDIAKEGSQLTLQDLAKFQPEVVDALEVPLGDYTLYSPPPPAGGAILSFILNVLRGFNFSTESMARPEGRVNVYHHLVETLKFAKGQRWRLGDPRSHPKLQNASRDLLGETLAQLIRQQIDGRGD-HQLSHYSLAEAWGHGTGTSHVSVLGEDGSAVAATSTINTPFGAMVYSPRTGIILNNELLDLCERCPRGSGTTPSPVSGDRVGGAPGRCWPPVPGERSPSSMVPSILINKAQGSKLVIGGAGGELIISAVAQAIMSKLWLGFDLRAAIAAPILHVNSKGCVEYEPNFSQEVQRGLQDRG--QNQTQRPFFLNVVQAVSQEGACVYAVSDLRKSGEAAGY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA52K7H2-1", "uniprot_id": "A0AA52K7H2_DANRE", "id": "A0AA52K7H2-1", "name": "Glutathione hydrolase", "aln": "MAKSQSRRCCFCLLALVCTAAIICICILFSKQKC-----DFTRAAVSADSLMCSDIGRDILRQGGSAVDAAIAALLCTGLVNPQSMGLGGGSIFTIMDN-TGKVKIISSRETVPKGVRRDLLKDCPRVLAIVTGSQWIGVPGEIRGYEEAHRLYGKLPWYKLFEPSIKLAREGFPMPEYLSQFIQHAYIKQILFSGTGLCELFCKNNNTEVLGPGDTLKFPQLAKTLETIAKEGADAFYSGKIAKDLIQDIQARNGALSLDDLKNFKVRVSDPWTVDLGEYKMHFPPPPAGGAILSFILKLMHEFGLSPASIQG-DQKNLTLHRYIEAVKFANGQRRFLKDPEFN---SGDMKSVTDEKFIKQIRALITDSGT-HEDSYYNITPAVD-RFGTTHVSVLAADGSAVSVTSTINHMFGSAVYSPKTGIILNNELVDFCNRADSVT-----------------------PGEQPPSSMAPAILQS--QQKTLVIGGSGGSMITSAMALSIMNHLWFGMNLNDSIAAKIVFVGSNNMVNFEKGYDSSAIKAMEKLG--HNVMYNPYFFNVVNGISKEGQCISAISDARKQGQSAGY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . .: **.: .:: :. ::* ::. *::***:*** :****** **:* **.***:****:**.:*********** :*** : ****::*.:***** . .**.:* ..*.: **:********:*** **** :*:*** :**:*:* * * *. :. **:*:::: :: * :.* * :** :. ** * . *.: :* **.****:*.**.:.:*:*::.: *::** ... *:::** *: .* :. : **:*.:: **************:::: *.:*. :: . *: :*::*** *** * ** : .. :.: * : : ** * . * *: *:*.:: . . **:*****. *****:.***** **: ****:***:*****:*:* * : ***:.****.*:** . * ..*****:**.:* **:* :**.:**:*::* :**: *:.*.*:. *::* :.... :.::. * :. .* *:*.*:.: :** *: * ** ** *:::**", "identical_positions": 243, "similar_positions": 183, "identity": "41.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110721-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TPD7-1", "uniprot_id": "LR75B_MOUSE", "id": "Q7TPD7-1", "name": "Leucine-rich repeat-containing protein 75B", "aln": "MGARLGRRAR--------------ADAPAAPSAG----------------------PAPYERRVRWLREIQSTLRERRPERARQLLRLLRQDLGLEGNLLTDILHRNVTFLNLVDPISHDLLVNLARDLQCPKKDHELWKSSDKICRQLIYHLTPHSKRK-----HHRKTQSSLKSSLQKTLLVGETVDLSGIPLSARDVQHISRYLDTRGVELVVLDLSFTELSDELLHLLLPSLWALPRLTQLLLNGNRLTRAAARELTEAIKDTAKFPVLAWVDLGNNVDVSSLPQPLLVGLRRRLSQHTSLPTIYEGLDLE-PGGGMAETTAAVSTWGSAATEAGPEPQG----------------CCAR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2VPJ9-1", "uniprot_id": "LR75B_HUMAN", "id": "Q2VPJ9-1", "name": "Leucine-rich repeat-containing protein 75B", "aln": "MGARLGRRAGPE----------AGSEAGAAAGCG----------------------PAPYERRVRWLREIQSTLRERRPERARQLLRLLRQDLGLERTLLPDILYRDVAFLNPVDPISHDLLVNLARDLQCPKKDYELWKSSDKICRQLIYHLTPHSKQQQGSSLRQRKTQSCLKSSLQKTLLAGETVDLSGIPLSTQDVQHITRYLSSHGAVLAVLDLSFTGLSDELLHLLLPSLWALPRLTQLLLNGNRLTRATARKLTDAIKDTTKFPALAWVDLGNNVDVASLPQPLLVGLRRRLSQRTSLPTIYEGLDLE-PEGSAAGATTPASTWDSTAAGLGPEPQA----------------CCAR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXP5-1", "uniprot_id": "E7EXP5_DANRE", "id": "E7EXP5-1", "name": "", "aln": "MGSKLTRQSSLDSQASFFRRGRQDHEERRTGGRGDFLFSSLMLRSDKLPGVLRRSSPCPYVRRVAWVREIQTLLKEQKLEQAIDVLKLLRKDLGLEGTSLNDILYKNAAFLNLVDPISHELLLNLARDLQCPKREADALKSSEKICRQLIYHLTPHSKWSR-QNVPRRKTQACLKTTLKKKLAN-DTVDLSGIPLSGRDLHRVAYYLQNNGSSVTAVDISFTELHDESLRLLLPYLGVLPKLSTLAINGNRLTVAILKDLIEVVKDPQKFPCLAWVDLGNNVDIFTVPQPLLVALRRRFGMRSSLPTIYEYSEGQGSSYCLETSVEEISVFEEEEEDEEDELEDHLVLEAWSVEEKNTLHFCER", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::* *:: : : . * *.** *** *:****: *:*:: *:* ::*:***:***** . * ***:::.:*** ******:**:**********:: : ***:*************** . :****:.**::*:*.* :********** :*::::: **...* :..:*:*** * ** *:**** * .**:*: * :****** * :.* :.:**. *** ***********: ::******.****:. ::******* : : . :. *.: . * : * *", "identical_positions": 157, "similar_positions": 81, "identity": "43.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110726-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4LDE5-1", "uniprot_id": "SVEP1_HUMAN", "id": "Q4LDE5-1", "name": "Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1", "aln": "--MWPRLAFCCWGLALVSGWATFQQMS-PSRNFSFRLFPETAPGAPGSIPAPPAPGDEAAGSRVERLGQAFRRRVRLLRELSERLELVFLVDDSSSVGEVNFRSELMFVRKLLSDFPVVPTATRVAIVTFSSKNYVVPRVDYISTRRARQHKCALLLQEIPAISYRGGGTYTKGAFQQAAQILLHARENSTKVVFLITDGYSNGGDPRPIAASLRDSGVEIFTFGIWQGNIRELNDMASTPKEEHCYLLHSFEEFEALARRALHEDLPSGSFIQDDMVHCSYLCDEGKDCCDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQINCPKDIEAKTLEQQDSANVTWQIPTAKDNSGEKVSVHVHPAFTPPYLFPIGDVAIVYTATDLSGNQASCIFHIKVIDAEPPVIDWCRSPPPVQVSEKVHAASWDEPQFSDNSGAELVITRSHTQGDLFPQGETIVQYTATDPSGNNRTCDIHIVIKGSPCEIPFTPVNGDFICTPDNTGVNCTLTCLEGYDFTEGSTDKYYCAYEDGVWKPTYTTEWPDCAKKRFANHGFKSFEMFYKAARCDDTDLMKKFSEAFETTLGKMVPSFCSDAEDIDCRLEENLTKKYCLEYNYDYENGFAIGPGGWG----AANRLDYSYDD---FLDTVQETATSIGNAKSSRIKRS----APLSDYKIKLIFNITASVPLPDERNDTLEWENQQRLLQTLETITNKLKRTLNKDPMYSFQLASEILIADSNSLETKKASPFCRPGSVLRGRMCVNCPLGTYYNLEHFTCESCRIGSYQDEEGQLECKLCPSGMYTEYIHSRNISDCKAQCKQGTYSYSGLETCESCPLGTYQPKFGSRSCLSCPENTSTVKRGAVNISACGVPCPEGKFSRSGLMPCHPCPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQSTGFNLDFEVSGIYGYVMLDGMLPSLHALTCTFWMKSSDDMNYGTPISYAVDNGSDNTLLLTDYNGWVLYVNGREKITNCPSVNDGRWHHIAITWTSANGIWKVYIDGKLSDGGAGLSVGLPIPGGGALVLGQEQDKKGEGFSPAESFVGSISQLNLWDYVLSPQQVKSLATSCPEELSKGNVLAWPDFLSGIVGKVKIDSKSIFCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGR---IFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESGWSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLP-MIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDFS-VNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKETRCETP-----------------------------------------------------------LEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPCP-VPFVIPEN-ALLSEKEFYVDQNVSIKCREGFLLQGHG-----IITCNPDETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNCSRKRRTGF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A1D5NSM8-1", "uniprot_id": "SVEP1_DANRE", "id": "A0A1D5NSM8-1", "name": "Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1", "aln": "MMVTLRLALTLRLTVLLLYWSGCTCWPSHAQQFSLQSLRQTSQARQN--------LSESAESKVERLGQVFRKNVRLLRERGGCLDLVFLVDESSSVGASNFKSELRFVRKMLSDFPVAPEATRVALVTFSSKSHVVTRADYVSAPKAHQHKCSLFSKEIPSITYRGGGTYTRGAFQRAAQILRQSRENATKVIFLITDGYSNGGDPRPVAAALRERGVEIFTLGIWQGNIRELHEMASQPKDQHCFFVHNFAEFEALARRALHEDLPSGNYIQEDLAQCSSLCDGGKDCCDLMASCKCGTHTGQYDCVCEKGYYGKGLQHECTACPSATYKPEAVAGGASTCLPCPDPHHTSRPGSTDISDCVCLEGYRPHNNTCQAVVCPVLSPPENGFFIQNVCNNQFNSACGVRCLPGFDLQGDGIRLCQPDGTWSGVQPSCRIRSCPDLSPPHHGMLNCSERSAPYRLECLVRCEQGYRLQGRARITCLANSQWSGPQPRCVEVRCPPIVTLKHIHLMPSTCGENEVRTGAVCQLSCPYGYSLIG-DSKVKCLPTGNWSDNLHKATCTDVEPPWIQCPGDVITETDEHQRSANVSLSAPMLRDNSGDEVMVQVTPVLNPMQTFPIGTEFITYTATDRTGNKANCSFTVTVVDTEPPLIDRCRSPPTVKATGRKTAVYWEEPQFSDNSGAQLNISSTHSSGDIFPVGETSVYYTATDPSGNNRTCELIITVRGSTCEKPFVPVNGDFSCAKTKEGMNCTLICRQGYSLAQNAVHSYFCANN-GIWEPPRSPDRPDCSLNRIANNGFKPFEMLFKASRCDDLNLVRSFSGEFSNVLKNTVPNICG-GDDVSCKLEMTLP-AQCLEYNYDYPNGFAIGPGGWGSNWGSQNGEDYAYFDSGFAPEHQLQKDASSQHGSHMRTKRHRKITGPTREQKIQIHFNITASIPLPLSRNDSAEIVNQKRLLRALEQLTNRLKRTLAKQPFSTFHVSSEMIVADPKSLESKKATLYCRPGSVLKGRVCVLCPVGTYFSLEYAECESCWRGSYQNEEGQMECKSCPDGSSTPYLHSRSQAECKAQCQPGSSSLTGLETCESCPLGEYQPGFGSQDCLSCPSTTTTVNRGALDVNECGVPCSAGHFSRTGLVPCYPCPRDYYQPEEGRSYCLSCPFYGTTTITGARAIQQCSSFGSSFLPKEESATT-APEVIVRKDYQASSQMFHECLLNPCQNQGTCEEVGVGYVCTCLPGFTGAKCESDIDECDSAPCQNGGLCRDGMGDFQCQCQPGFVGLLCEAEVNECSSSPCLNEGICVDEVNYFSCSCPDGFTGPRCEMEINECASSPCQNEGVCKDLEGGYFCTCAQGFTGDNCEVDVNECYSAPCLNGGTCVDAINDFRCECVNGYRGRLCQVDVDDCELNLCLNGATCVDGVATFTCRCPPGFNGTRCETEMPYSFDLEFEVSGIHGYVMMDGHMPSLTQITCTFWMRSSDTVNYGTPVSYAVE-GSDNAFLLIDYNGWVLYVNGKERITDCPAVNDGLWHHIGVTWRSKDGDWRVYIDGSPSDGGKGLSIGTTIPGGGALVLGQDQDQRGDGFNPVESFVGTLSQLNIWNYVLTPQQIRSLASSCPHDLQKGNVFAWPDFLGGVTGRVKTTSKSIFCADCPLVETSVPHLLSSSKAVSPGSKVQFSCSPGFYLVGEPVQLCLNRGQWSHAEPICERVECGPPPDLEHGQYHGEDFYAGSSVLYQCKPGFYLLGESKMQCTNNGKWIGNPPACLDVDECSLGSECDEHASCQNTDGSHICTCIAPYSGDGRNCTEPVKCKDPGVPEFGQREGTNFIMGSEVVFSCKEGYELIGSSQLTCTEEGFWKQDVPYCKALSCPHPTLPKYGILKGANFTYGSKVTFSCEKGYVPLEPIESQCQSDLKWSREPHICQPITCGEPPVVDYAEYTLNGKIYRSTLSYTCIEGYRLQGAMELQCESSGEWTSPPPMCARVDCGKPPPLKDAVIKGDNFTLGSKIYYICKDGYTLLGAETQECLPSGNWTRNSSQCVPRSCGPPPQVDHALPDTGHQLFGDIAIYFCDDGYTAGNNTKLFCNAQGVWAPPDGFGIPHCIANFCQRPPDLPHAILDSINKPKYASNTEVSYKCEEGFVLNTTGTLKCLIGGEWTPSPSDIGCMPVRCSKPESIEKGYVSGNNYGFGAVIAYSCDKGYFIRGEKKRICKASGEWGGVLPTCQPISCPSPPRLANGFIQGQIRKNSYVYNSKVTYACNDGYRLTGKPERTCMANKQWSNSNSLVCVLLTCPTPPDIKNGLYHGSTFEVGSKVEFVCNEGYELIGDTVWTCLKFGNWDKSIIPRCSPVQCPEPPLEENHLVLRGLDSDSGTVELSCEEGYVLHGARTLRCTPSQEWNDSFPVCKQVFCGPPPEVAFGDPS-DTQSYFGSVVTYSCMDGFTLRKEGSVHCQANGNWSKPYPQCIPVECPHPEDIPNGIVDVQGLMYLSTAVYSCKAGYDILGNSTVLCGQSGQWIGGIPVCHPVKCAAPKEIPNGSVRYSKLQFSQSITYFCQRGYRIQGPETLTCLENGQWDQEAPTCVPIYCSPPKPIDNGFVEGRDRKFGVTIFYSCFPGFLLVGNNHLTCEDHGWSSSEPKCVLADCGLPPHIDFGDYSKVQELS----AEYDMVT---------------------SQQLPVDNS--FLHGSLVKYHCHSGYEINGAIMLMCREDGTWNGTAPMCTPAQCEAPPSPENGSVMVTDSALGSLAEYSCAEGYELNGQTIRQCISGQQWSDDAPRCLPISCGNPGGIANGEVIGKSFHFKELIHYECHSGFVLEGVETRTCQVDGKWDNKAPLCKEVSCGRPVVSKDVLVRGDDHTFGKRLLFSCNLGFILLGAPTIVCLANGSWNEVPPKCLPANCGQPPSIENGRVTGTDYGYNGMVRYACDIGYVLTGNPTLICRADGLWDDPPPRCDIITCDPPEDISHGYLNGSSFNFDDIVEYICFPGYEVVGSPILRCAAEGVWLGQVPECRPCVCSPPVFKYGSILGRDHTCGASIWFRCDDGYKILGSSEAICDKGGVWSPGVPICTRGRCSIPPPAVPNAVIQGSTAYTIDTVTYRCRPGYHLKGFPHISCGRLGRWGEPNLSCEPISCGVPPLISNAETVGAVLTYGSKAQYRCKEGFELATKTDSITCQSDGTWSKHGVRCRPSPCTLPTNLTHVVITGKQLTPVGGTVIVSCRPGYYLEGPGLSECTVSGKWSPPLA--SCLPVICEKPLPILNGLVEGISYNYGDVVNFTCQQGFLLQGHSVRTCQGDKTWSGTQPVCAAVSCGPPPVVPNAVASSSGQTYKSIVSYTCRQGTSLVDSQNLTCQANGSWSLPTPICEVPGGCEKITDLLNGKVQEHNLSSGRALEFHCNKGYTLQGESLVMCVGNGSWSSPFPVCLPKPCPPLPHGWTVGSANATQTVFSVGQSVQVSCPKGQRVKSNQGKGIATLTCRSDQTWTPISAVCERVSCGPPLYVSNGVVRGAVFQFGDMVLYSCYAGFTMEGSSRSVCLDNGTWTQPPTCKAVCWRHCQNGGVCQRPNTCSCPEGWMGRFCEEPICILPCLNGGRCVAPYQCECPAGWTGTRCHNAVCSMPCLNGGRCIRPNRCHCSPGWGGYDCSRKRKSAYFHF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ***: .*: *: . :::**:: : :*: . . .*:* *:******.**:.****** . *:******:***** **:*** ****:******.* *****:******.:**.*.**:*: :*:****:*: :***:*:********:****:***** ::***:***:***************:**:**: ******:**********::*** **::**:::*.* *****************.:**:*:.:** *** ****** *.*********:::*:***********:*******.*****. .** *:*:**** :*** ****. .**** ****. .:**: * **.*.*****:****.***:**:****** ***** *..* ** *:* *** :. **:*:**.* *:** :.** *. *: *** *::****:* ::** .****.**:***** :*..: *.: : * .**:: .: *::* :** *: * * .. ::* .:*:*. .:: *.*.***.* *:** *: ::* *:* ****: . * :****::* *:* *.:.* **** *.***** :**:*.* * :.*:*:***:** *****.*:.: : *. *:**********:* *: :*:.**:** *** * *************:: *.::**.** **.****** *: : *:**** * :**.:::.:...*:** : *:*:*. :.: ***: :*:**:***.***::**:**** :*::.** *...* : **.:*. .:*:.*:** .*. ******** *********** : * **:* * : :. :* :.. * ** .* : **:: ******:*** .***: * **:***::** :**:***** *:*: :*:::**:::**.:***:***: :*******:**:** **:***:.**: **** ****:****:*** **.* * *:***. ::*****: *: * :*********** *** ***:.*****..*:**:***:::. *****. *:***:**:**:*********: *:::**:*******.::*:*:* :****.*:* . ***... *. ::* :: ***:****::***:*.***:::* **** * *:** ***:*****.. ** *.*:*:* :*:* *:* .*:.* ** ::**********:***** * : *:* .**.* :** *:*** *.** *:.**:* **::*.*. ** * .* :*:** * ** **.** *. *.*** *. *: * *::::::*: * * * ***** : :::*:* ***.*.***** . .*:*:******:****:** :*** :******:*** :*****:****: ****::** ***********:*:**:**:**** ****.:** * :* *:*****. **** ***:* .***********:**::*:**.*.*****::****:*:***:***::***:***.:*.****:******.*:.*:** ******:*** : ***** ::*: :.*****:: *.*** ***:*** ***:***::. * ***:.** ** **:* : .:******:* ***: *:****:*:* **:**.* * .*:*******::**:*.***** *.***:**:*:.**:***:**:**:*** ** ** *: .* : :*:**.***:***:*:* :::** *.* *:: :*****:** :*::*: * :: **:*****: *:***. **.* :: .**:.* :*:*:.*..* :: .:* *.* * ** **:* ** ***. ::* :** * .** * * **:**.:*****.*:***: ..: * **:**** * :* ***..*:*:*...**:. **. ** **** *:*.*:******:*:*.***: .:*::*:***** *.**:* .:*:***:**::**.:.::**:*:.*.*:*:.: **:** *******:..::*: **:*.*** .* *:****.:* ** :**.**.**.***::****:**::*:**** *:*:*:*.. :***:*:** .**:: ***:: : :::*:* * ** **: .*.* .* **::* ....*:** * * .** *:**: :*..*******:*.*******:**: *** * *:*:*. *:* *.:****** **:***: * :: *.* :**:**:**:*. .*:* ***:********* *:* *** ::** * .: :***.*.***:.** ** :.:. **.:*.**.* *:*:*****:**:*****:***** *****:*:**.*::::**:*.***:.*:*:** *.*:.::* **** **.. *:.*::.*::** *:**:*::**.:*****.*:** :**:* .*:*..*:**:****** * .:*. *:******* :.*: ***: ***** *.*: ************ :*::: . * **: ::: *. :* **:*::*.* *:.***: * :*:*:*******:** * . :*: *.:**** : .*::::** .:*** *: * *. :* *:..::**. :*** .*** :*. : **.: *..: : . ::***..*:**:*.* **** * :**:. *:* *.*. * ** : ****::** *.: ::** **:* ** : ********. ..*.*:*..*. **.: ** . * ***: * : *. **:* * *.* *::** ** * *. :.*.****::**: ** ** ... ::* *****:: *.. ** ::* * *. *.* ** **.**::**:: * *. ** : ::* .*:*:** ** *: .* **.*.* * : *. * :***.*. ::::. :.:** **.** ::* ..: * . * *.:* ***:*** ** ::** :.* . ** *:.: ** **: : *.**::***.** * . : * *. *.** *:**::: *.::: *. * *** ** :** .:* * :.*.*.**:: ** ** * ** . :*:* * .*.: ..: : *: *: *:*: *.** :: *** .:* . * .* ::****.: .* ::* : : **:**:*:* * . *. **:** *.*:* *:*** :*. . . * ::. * *.*.*.:.* :* ::.: :**..*:*** ** **::***** :*.*.:.**. :*:***: ****:*: :** *****:*****.** *:*** *****:*****:**********:**********************:**.****:***.***. ******:*:******* ..* *::*****::.: ", "identical_positions": 1899, "similar_positions": 1016, "identity": "51.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110728-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NS56-1", "uniprot_id": "TOPRS_HUMAN", "id": "Q9NS56-1", "name": "E3 ubiquitin-protein ligase Topors", "aln": "MGSQPPLGSPLSREEGEAPPPAPASEGRRRSRRVRLRGSCRHRPSFLGCRELAASAPARPAPASSEIMASAAKEFKMDNFSPKAGTSKLQQTVPADASPDSKCPICLDRFDNVSYLDRCLHKFCFRCVQEWSKNKAECPLCKQPFDSIFHSVRAEDDFKEYVLRPSYNGSFVT-----PDRRFRYRTTLTRERNASVYSPSGPVNRRTTTPPDSGVLFEGLG-ISTRPRDVEIPQFMRQIAVRRPTTADERSLRKIQEQDIINFRRTLYRAGARVRNIEDGGRYRDISAEFFRRNPACLHRLVPWLKRELTVLFGAHGSLVNIVQHIIMSNVTRYDLESQAFVSDLRPFLLNRTEHFIHEFISFARSPFNMAAFDQHANYDCPAPSYEEGSHSDSSVITISPDE----------AETQELDINVATVSQAPWDDETPGPSYSSSEQVHVTMSSLLNTSDSSDEELVTGGATSQIQGVQTN--DDLNNDSDDSSDNCVIVGFVKPLAERTPELVELSSDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNLNSSVRGDRVYSPYNHRHRKRGRSRSSDSRSQSRSGHDQKNHRKHHGKKRMKSKRSRSRESSRPRGRRDKKRSRTRDSSWSRRSQTLSLSSESTSRSRSRSSDHGKRRSRSRNRDRYYLRNNYGSRYKWEYTYYSRNKDRDGYESSYRRRTLSRAHYSRQSSSPEFRVQSFSERTNARKKNNHSERKYYYYERHRSRSLSSNRSRTASTGTDRVRNEKPGGKRKYKTRHLEGTNEVAQPSREFASKAKDSHYQKSSSKLDGNYKNESDTFSDSRSSDRETKHKRRKRKTRSLSVEIVYEGKATDTTKHHKKKKKKHKKKHKKHHGDNASRSPVVITIDSDSDKDSEVKEDTECDNSGPQDPLQNEFLAPSLEPFETKDVVTIEAEFGVLDKECDIATLSNNLNNANKTVDNIPPLAASVEQTLDVREESTFVSDLENQPSNIVSLQTEPSRQLPSPRTSLMSVCLGRDCDMS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ICA2-1", "uniprot_id": "A0A0R4ICA2_DANRE", "id": "A0A0R4ICA2-1", "name": "E3 ubiquitin-protein ligase Topors", "aln": "-------------------------------------------------------------------MAPSKMKLRVR---KKDSASKTSQRLLANASPDSKCPICLDGFNNVASLDRCLHQFCFRCIHEWSKNKAECPLCKQPFHSIFHSVKGENDFKEFVLWPPENGAANANAADPSERVLRPRVLRRRERRSNRVQTPAPS---STPPIEDDVMFDGLSDAAALAENQDVQQMMLRLTARRAGRGEGRSLRRLREQDVVAFRRALYRTGVRVRSARDASRQRDISASFLRQNPGCLRRLLPWLQRELTVLYGSHGSLVNIVQNVIISRIMNYNMEESIIRDELRPFLLARTDHFLHELVSFARSSLNMEAYDLQAVYDCPAPSYEEGSSSDLSVIAISEDEEDNDSENNVIENPSAVQERIASVATASGTDSLLSQSAWDDETPGPSYSSILQSSNQSQDEGAEPSSSTAPPLASTDGTDPAAISAADEEEECLIVGYVKPMAERTPELVQLSSDSSEE-----------EEQQAAATETPATVTKSETGQSQLPLPSHMKPLSPSSFAGPAPSCSPQANPSVPQEILSFSRERESDYYSSHGHRSR-------LASWSELRVHGRRKDRSHRHNKEKAKSIEQIQQPTTLECSPMHSPQSWSGQSSAVS-ICSISPGSPSYDSDYSPSPKTKGRKHSCRVQERIRQSPSYSGR-KSTKERMSRSPDLDLFIGSHHPRESKRHRKRRKRSVSSSSADSHSEKSCLDKPSGKRKYKTRHLERAAQRQHEEGNPSKEKRSKLRSRDRSPSVEIIYERRAPD-PHWVSRKKKKKHRKRRKDLDSPTVITIDSDSDRTIDCLDRVMDVIDQTAADIEQRDGTSEQAETCTVASSNLFSESSSPVRPSDPTNEQSLNLDDC----VVDVVDQSSSDCSHNIDSSNHEEIVPDPFPMSSITTAPSSDTRLLESILQDLEEFLPAEEPEIGQSACARSPVQQDLTSVPP-----------KDQSDTGGDVDN-SENKTTGGDEPQEMATNTAS--------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.: :::: * .:** .* : *:************ *:**: ******:*****::****************.******:.*:****:** *. **: : .:* :* *. ***.:. ....* :*.* :..*:*:**. :: ..: :: *:* :::.**. .: ****:::***:: ***:***:*.***. .*..* *****.*:*:**.**:**:***:******:*:*********::*:*.: .*::*.. : .:****** **:**:**::*****.:** *:* :* ************ ** ***:** ** :.. :: .:*:*: *. *. . * ..* : **:*::*:.*::* . .::: ..*: * .: *..::*:***:***:********:*****.: :**: : :. : *::..: :* * .::: .* : .. . : ..*:.. * * . **.:.** * * *: * :*:: ::*.*:: ** .. .: :: . .. :* : :** ::* .* * . . * *.. *: .* ::* .*..* * **. * * : .*:: * .* : *: * .. .:*.**:: * ..: : * : ** .*. ..... . . .. * *:..*. : *: * : .: *:: .:: * :.. . : .:*.: .. * :. . :* . .:*. * ..* ..:. :: . : .. .:.:. : *:. ** .:*..*.. *. :.:: :: *: ..: :.. . . : : : * : :* :*. : . .:: : .:** :::* .*::* ..* .: **.. ... : ", "identical_positions": 299, "similar_positions": 346, "identity": "28.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110728-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7EVZ0-1", "uniprot_id": "F7EVZ0_RAT", "id": "F7EVZ0-1", "name": "", "aln": "MRSCRRLDQLQAGLCLLLASLQLVSWTLAEPVDVLETLGVHRDKAGVTKGPGFCPQR--IPQGDRAFRVGKSSLLSVPTWQLFPDGHFPENFSVLLTLRAQPANQSVLLSIYDENGVRQMGLALG--PALGLLGDSFRSLP------KQINLMDGRWHRVAVSISGDKVTLVVDCE-PQPPMFGQGPR-VISTAGLTVMGTQELGEESFEGDIQELLLIPDPQAALQACELYLPDCETPDSTTTGVTKEEPETPAPRRR-KGKGKKKDRGRKGKGRKKNK-TSRLSPTPGAPENQTSLHTPETEKPSPHLPPTPTPLAITTTVTMGGNATVLQG-LDSSTETEQMTPEMDAT-EESEGGGPTMGPEFRAAEQSLQTEFQIFPGAGEKGAKGEPATIEQGQQFEGPAGAPGPRGISGPSGPPGPPGFPGDRGLPGPAGLPGIPGIDGVRGLPGTVIMMPFHFASGSMKGPPVSFQQAQAQAVLQQAQLSMKGPPGPVGLTGRPGPVGLPGYPGLKGELGEAGPQGPRGLQGPPGPPGREGKTGRAGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGPVGQPGPPGEDGIKGLQGPPGPTGQAGEPGPRGLIGPRGPPGPLGRPGVTGSDGAPGAKGNVGPPGEPGPPGQQGNHGSQGIPGPQGPIGTPGEKGPPGNPGIPGVPGSEGPPGHPGHEGPTGEKGAQGPPGSAGPQGYPGPRGVKGTSGNRGLQGEKGERGEDGFPGFKGDEGPKGDRGNPGLPGPRGEDGPEGQKGPEGLPGDEGPPGAAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPLGEKGKRGKAGQPGEEGERGTPGTRGDRGQPGATGQPGPKGDVGQNGSPGAPGEKGLPGLQGPPGFPGPKGPPGPQGKDGIPGHPGQRGELGFQGQTGPPGPAGVLGPQGKVGDVGPLGERGPPGPPGPPGEPGLPGIEGREGAKGELGPLGSLGKEGPPGPMGFPGPQGAPGDPGPIGLKGDKGPPGPLGANGSPGERGPVGPSGGIGLPGQSGGQGPIGPAGEKGSPGERGVPGPTGKDGIPGPPGLQGPPGAAGPSGEEGDKGEVGMPGHKGSKGDKGDAGPPGPTGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPPGPSGSAGSPGLPGGVGQPGAVGEKGEPGNAGDAGPPGVPGIPGPKGEIGEKGDSGPSGAAGPPGKKGPPGEDGAKGNMGPTGLPGDLGPPGDPGVPGTDGIPGEKGNAGDIGGPGPPGASGEPGARGLPGKRGSPGRMGPEGKEGEKGAKGDAGPDGPPGRTGPIGARGPPGRVGPDGLPGIPGPVGEPGLLGPPGLIGPPGPLGPPGLPGLKGDAGLKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGLQGDPGLPGPVGSLGHPGPPGVVGPLGQKGSKGSPGSLGPRGDPGPAGPPGPPGSP----AEVHGLRRRRSVLDTP-----------------------EGGLEEVMASLNSLSLELEQLQRPPGTAESPGLICHELHRNHPHLPDGEYWIDPNQGCARDAFKVFCNFTAGGETCLYPDKKFETVKLASWSREKPGGWYSTFRRGKKFSYVDADGSPVNVVQLTFLKLLSAAAHQRFTYTCQNSAAWLDEASGDHRHSIRFQGTNWEELSFNQTTAATIKVPHDGCRVRKGQAKTLFEFSSS-VGFLPLWDVAAVDFGQTNQKFGFELGSVCFSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P25940-1", "uniprot_id": "CO5A3_HUMAN", "id": "P25940-1", "name": "Collagen alpha-3(V) chain", "aln": "MGNRRDLGQPRAGLCLLLAALQLLPGTQADPVDVLKALGVQGGQAGVPEGPGFCPQR--TPEGDRAFRIGQASTLGIPTWELFPEGHFPENFSLLITLRGQPANQSVLLSIYDERGARQLGLALG--PALGLLGDPFRPLP------QQVNLTDGRWHRVAVSIDGEMVTLVADCE-AQPPVLGHGPR-FISIAGLTVLGTQDLGEKTFEGDIQELLISPDPQAAFQACERYLPDCDNLAPAATVAPQGEPETPRPRRKGKGKGRKKGRGRKGKGRKKNKEIWTSSPPPDSAENQTSTDIPKTETPAPNLPPTPTPLVVTSTVTTGLNATILERSLDPDSGTELGTLETKAAREDEEGDDSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAP----AELHGLRRRRRFVPVPLP-------------------VVEGGLEEVLASLTSLSLELEQLRRPPGTAERPGLVCHELHRNHPHLPDGEYWIDPNQGCARDSFRVFCNFTAGGETCLYPDKKFEIVKLASWSKEKPGGWYSTFRRGKKFSYVDADGSPVNVVQLNFLKLLSATARQNFTYSCQNAAAWLDEATGDYSHSARFLGTNGEELSFNQTTAATVSVPQDGCRLRKGQTKTLFEFSSSRAGFLPLWDVAATDFGQTNQKFGFELGPVCFSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z682-1", "uniprot_id": "A0A8M6Z682_DANRE", "id": "A0A8M6Z682-1", "name": "", "aln": "-MKMKSYRISGVSSLLMALFLQNTTLAAANPIDVLKVLDLSESMEGVSLEAGLCSSRRGSEEADLAYKIDKKIQVSVPTSQLFPDSEFPVDFSVLLTVRARRGAQCFLLSVYDSEGVQQLGVELGRSPVFLYEDQSGRPSPDLYPIFKKINLADGKWHRVAYSVEGQKVTLYLDCQKVATLDLPRGPEPKVSTAGVTVFGTRLLDEEVFEGEIQQLLISPDPGAAADYCHTHIPDCDS-ALTYNSLSLDPVEVNRPQRK-----------PVEEEFEDDLYSDLYSDLPNADQNSTEYELLEYE--------------------------------DSENGTEYVKEYTEYD--------EYVEYEYRPAERQDQ-HFSSQSRGPEKGEKGEPAVLGEGTMVTGPPGLPGVEGPQGERGPTGPPGRIGDPGDPGPEGRQGLAGADGIPGPPGNLLMLPFQSGGDARLGPVISAQEAQAQAILQHTKLSLKGPPGPLGLTGRPGPLGSPGPRGLKGDHGLTGPPGPRGVLGAPGQNGKPGKRGRGGMDGGRGEPGETGVKGDRGFDGLPGLPGNKGHRGDTGKKGPVGPPGAPGEKGSDGQPGPRGQSGEPGLAGLTGQRGLPGPPGQQGIRGIDGVQGSKGNLGPPGEPGAPGQQGNPGFQGFPGPQGPVGVPGEKGPQGKKGMKGLPGVDGPPGHPGREGPPGEKGLPGAAGVQGPVGYPGARGVKGADGLRGLKGSKGEKGEDGFPGAKGEMGAKGDNGDAGAQGMRGEDGPEGPKGQSGPLGEPGPAGIAGEKGKLGVPGLPGYPGRQGQKGGDGFPGAVGVPGEKGKKGPPGPAGAAGQRGPNGARGARGARGPTGKSGDKGTSGHDGPPGSTGDRGPQGPQGRVGEMGPKGPNGPAGKDGLPGHPGQRGEPGFQGKTGPPGPTGVVGPQGNTGETGPMGERGHPGSPGPAGEQGLPGAAGKEGSKGDPGGQGTSGKNGPTGLKGFRGSRGAPGAMGPVGLKGGTGPIGPPGPAGPTGERGPPGLAGAIGQPGRPGTSGGPGPMGEKGEPGDKGLIGPAGQDGEQGPVGLPGAAGPPGPPGEDGDKGETGAPGQKGSKGDKGESGPPGPVGSQGPEGQPGAPGVDGEVGPTGQQGMYGQKGDEGARGFKGSRGPGGLQGMPGPPGEKGESGNSGLLGPPGQFGPRGAQGPSGGQGPPGRPGVRGQPGGVGEKGEDGESGDPGAVGVSGSAGEKGEQGEKGDTGPPGAAGSAGARGASGEDGAKGNGGPIGLPGDMGAPGEPGVNGIDGTAGSKGDAGDPGKPGPPGPFGEPGPPGRPGRRGHLGPPGKEGRPGLKGDKGAPGYEGIIGKPGPVGGQGTSGKPGPQGLPGIPGPAGEQGLNGPPGQSGPPGPMGPAGLAGLKGDPGKKGEKGHGGLIGLIGPPGEFGEKGDRGLPGNQGPQGAKGDEGPVGPAGLTGPPGPPGLSGSMGQKGSKGNQGPIGARGDPGPAGPPGPPGSAAVGMAAPPALGKRRRHVEVSVDGAALEEAGSQVEQQMEEVQTEEVQMEEVFASLASMRTDVEGLRTPLGSFHSPARTCRELRLCHPEYPDGVYWIDPNQGCHRDAFKVFCNFTADGETCLQPHSSVQTVKMASWSKEKPGTWFSTFKKGSQFSYVDVDGNPVHVVQLGFLKLLSATARQSFTYVCQNSAGWLDGSTRSYTHALRFRGSNGDELT--QRNTHYIQPTHDGCQWRSGQERTVLQLDAPLPDVLPLLDVSVSDFGSLKQKFGFSVGQVCFSG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : .. *: ** . : *:*:***:.*.: . **. .*:*..* :.* *:::.: :.:** :***:..** :**:*:*:*.: . *..***:**..*.:*:*: ** *.: .:. *. * :::** **:***** *:.*: *** **: . : :**. :* **:**:**: *.*: ***:**:**: *** ** : *. ::***:. : . . *. *:*: : :.: * *.: :*.*. . : * *... ** . . : ::*.** : .*. . . *** *****.: :* . **.* ** .* * **.**** ** * *** * *:.* **: * **.::*:**: ...: ** :* *:*****:**:::**:******:********:* ** ****: * ** ****: *. * *: ** ** * **.** **:** **************:**:*** * * **** * :* :* *** **:**** ** * ** *** *: *: * **. *:***:*******.****** * **:***** :*.****** *: *: *:** :** ****:***.**** *..* ** ****.*****:.* ***:*.***:******* **: * ***.*..* * ******** ** * *: **.* ****************** * **. ****.:* ***** * .* .* *:**. *:** ** *.**:.* ** *::*.** .*::* * ** * ***** * **** ********* ****:******:**:****:.*:.**:**** **.***.** **** *:**:**: * *. **:**.* ** *.:*.** ** ****..** ** *. *..***** * :*.** **:.* .* ** *:**. *::* **:*:** ** * *..*..**.**:****:.* **:********::**** * :** *:**.**.** * * *::*****:*.*** * ** ****:********* *: * :** * ****. **:*. *.** ** ****.****** *::**.*. *..* .* **: *****:**.****..* :*..*******. ** *****:*.**:*** * ** .*.**:.** * *****. ****. * **:** * * **: * ** ** .* :* *:.**:*.:*..*: **:** *****.** ** *.** *****:**.**.*****.* ****** *********** *****:**** *** * :** * ** * * *****: *.:*******. *.:*.***.**********:. * .* :** : .. * :***:*** *: ::* *: * *: . *. *:**: **. *** ********* **:*:*******.***** *....: **:****:**** *:***::*.:*****.**.**:**** *******:*:* *** ***:*.*** :: .: *: ** *:* :**: * .: :. .:***: *.** :*::::.:. ..*** **:. ***. :*****.:* ****.", "identical_positions": 915, "similar_positions": 388, "identity": "51.4%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110804-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LMA9-1", "uniprot_id": "F1LMA9_RAT", "id": "F1LMA9-1", "name": "NFX1-type zinc finger-containing protein 1", "aln": "MEDRR--PHLEATPRNPPTNHRGPIDG----EVPPRARNQANNPAA-----------------------TNHAGRHPRASNHAAPFRQREERFRAMGRNPHQGR-----------------RNHEGHTSDEARDQRQSQ-NDTRR--------------------------------------RNDDQEGRNHRPPWSSDSFQQWHTPLQ-----------------KPAEQPQHTKRLGYKFLESLLQKEPSEVAITLATSLGLKELLSHSYMKPSFLQLICQVLRKACSSRIDRQSILHVLGILNNSKFLRVCLPAYVVGMITEPVPDIRNQYPEHISNIISLLQDLVSVFPASSVQETSMLISLLPTSLNALRASGVDIEEETEKNLEKVQAIIKHLQEKRREGTLRVDTYTLVQAEVEG--EVESYRAMPIYPTYNEVHLDERPFLRPNIISGKYESTAVYLDTHFRLLREDFVRPLREGILKLLQSFEDQC-----LRKRKFDDIRIYFDARIITPMCSASGIVYKVQFDTKPLKFVRWQNSKRLLYGSLVCMSK-DNFETFLFATVSNREHEDLCQGIVQLCFNEQSQQLLADVQPSDSFLMVETTAYFEAYRHVLEGLQEVQEEDVPFQRNIVECDSYVREPRYLLMGGK-YDFTPLIENPSAIRKSLRGAEVLRRSKINVLDFSQWPVKEALNLDDSQMKALQFALTRELAIIQGPPGTGKTYVGLKIVQALLTNKSVWQISAQKFPILVVCYTNHALDQFLEGIYGCQKTSIVRVGGRSNSEILKQFTLRELRNKREFRRTLPMHLRRAYMNIVTEMKESEQKLQVGAQTLECTMHGVLREQHLEKYIAPQHWESLMNGPVQDADWLCVQPSKHSMIVEWLGLGVGSFTQSASPAGPENTAQAEGEEEEEGEEEGSLIEIEEEADLIQADRVIEEEEVVRP-RRRKKEENGADQELAKMLLAMRLDQDVPG------TTAGPEQAAE-EWETQRSQKKKMKRRVKVELRKLNTITEAEASAIQDVWQLDLSSRWQLYRLWLQMYQSDTRRKILSYERQYRTWAERMAELRLQEDLHILKDAQVVGMTTTGAAKYRQILQQVEPRIVIVEEAAEVLEAHTIATLSKACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFERLVKVNVPFVRLNYQHRMRPEIARLLTPHIYQDLENHPSVLKYEQIKGVSSNLFFVEHNFPEQEIQEGKSHQNQHEAHFVVELCQYLLCQ-EYLPSQITILTTYTGQLFCLRKLMPVKTFAGIKVHVVDKYQGEENDVILLSLVRSNQEGKVGFLQIPNRICVALSRAKKGMYCIGNMQMLAKVP--LWSRIIHTLRENHQIGPSLRLCCQNHPETHTLVSKASDFQKVPEGGCSLPCEFRLACGHVCTRACHPYDSSHKEFQCMKPCQKVICQDGHRCPNVCFQECQPCQVKVPKIILKCGHKQMVPCSVSESDFCCQEPCSKVLRCGHRCSHLCGENCVRLCPEKVTVKLNCGHSQLVKCGQVEDLKYG-LPVKCTTKCDTTLDCGHACPGSCHSCFEGRFHERCQQACKRLLVCSHKCQEPCMGECPPCQRTCQNRCVHSQCKKKCGELCSPCVEPCTWRCQHYQCTKLCSEPCNRPPCYVPCTKLLACGHPCIGLCGEPCPRKCRVCHLDEVTQIFFGFEDEPDARFVQLEDCSHIFEVQALDRYMNEQKD-----DEVAIKLKVCPICQVPIRKNLRYGTSIKQRLEEIETVKEKIQGSAGEIAASQERLKALLKSKTLFHQLRPEEFLILQEKLTQKNLSVKDLCLVENSISFYDHLANLEGSLEKVHQLERQKVR------TRLEQVHEWLARRRLGFSSQELSDLQSEIQRLTYLVNLLMRCKITE---VKGSIAEEVSSIRNILEKTCKFTQEDEQLVQKKMDALKTTLPCSGLGISEEERVQIVTALGVPRGHWFKCPNGHIYVITECGGAMQRSTCPECQEVIGGENHTLERSNHLAPEMDGAQHPAWSDTANNLMNF-EIHRMM-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R151-1", "uniprot_id": "ZNFX1_MOUSE", "id": "Q8R151-1", "name": "NFX1-type zinc finger-containing protein 1", "aln": "MEDRR--PHLEARPRNPPANHRGPMDG----ELPPRARNQTNNPAA-----------------------TNHAGRHLRASNHPAPFRQREERFRAMGRNPHQGR-----------------RNQEGHTSDEARDQRQSQ-NDTRR--------------------------------------RNDDQEGRSHRPPWSSDTFQQWHTPPQ-----------------KPGEQPQQTKRLGYKFLESLLQKEPSEVAITLATSLGLKELLSHSSMKPSFLQLICQVLRKACSSRIDRQSILHVLGILNNSKFLRVCLPAYVVGMITEPSPDIRNQYPEHISNIISLLQDLVSVFPASSMQETSMLISLLPTSLNALRASGVDIEEETEKNLEKVQAIIKYLQEKRRQGSLRVDTYTLVQAEAEG--EVESYRAMPIYPTYNEVHLDEKPFLRPNIISGKYESTAVYLDTHFRLLREDFVRPLREGILKLLQSFEDQC-----LRKRKFDDIRIYFDARIITPMCSASGIVYKVQFDTKPLKLVRWQNSKRLLYGSLVCMSK-DNFETFLFATVSNREHEDLCQGIVQLCFNEQSQQLLADVQPSDSFLMVETTAYFEAYRHVLEGLQEVQEEDVPFQRNIVQCDSYVRNPRYLLMGGR-YDFTPLMENPSAMRKSLRGAEALRHPRINVFDFGQWPSKEALKLDDSQMEALQFALTKELAIIQGPPGTGKTYVGLKIVQALLTNKSVWQINTQTFPILVVCYTNHALDQFLEGIYGCQKTSIVRVGGRSNSEILKQFTLRELRNKREFRRTLPMHLRRAYMSIVTEMKESEQKLQEGAQTLECTMHGVLREQHLEKYISAQHWESLMSGPVQDADWVCVQPSKHSMILEWLGLGVGSFTQSASPAGPENTAQAEGEEEEEGEEEGSLIEIAEEADLIQADRVIEEEEVVRP-RRRKKEENGTDQELAKMLLAMRLDQEVPG------TTAGPEQATE-EWETQRGQKKKMKRRVKVELRKLNTMTKAEANGIQDVWQLDLSSRWQLYRLWLQMYQADTRRRILSYERQYRTWAERMAELRLQEDLHILKDAEVVGMTTTGAAKYRQILQQVEPRIVIVEEAAEVLEAHTIATLSKACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFERLVKVNIPFVRLNYQHRMRPEIARLLTPHIYQDLENHPSVLKYEQIKGVSSNLFFVEHNFPEQEIQEGKSHQNQHEAHFVVELCQYLLCQ-EYLPSQITILTTYTGQLFCLRKLMPVKTFAGIKVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQIPNRICVALSRAKKGMYCIGNMQMLAKVP--LWSRIIHTLRENNQIGPSLRLCCQNHPETHTLVSKASDFQKVPEGGCSRPCEFRLACGHVCTRACHPYDSSHKEFQCMKPCQKVLCQDGHRCPNVCFQECQPCQVKVPKIILKCGHKQMVPCSMSESEFCCQEPCSKILRCGHRCSHLCGEDCVRLCSERVTVELKCGHSQLVKCGNVEDIKYG-LPVKCTTKCDTTLDCGHPCPGSCHSCFEGRFHERCQQPCKRLLICSHKCQEPCTGECPPCQRTCQNRCVHSQCKKKCGELCSPCVEPCVWRCQHYQCTKLCSEPCNRPPCYVPCTKLLACGHPCIGLCGEPCPKKCRVCQPDEVTQIFFGFEDEPDARFVQLEDCSHIFEVQALDRFMNEQKD-----DEVAIKLKVCPICQVPIRKNLRYGTSIKQRLEEIEIVKEKIQGSAGEISTSQEQLKALLKSKTLFHQLRPEEFLILQEKLAQKNLSVKDLGLVENSIRFYDHLANLEGSLEKVHCGEQQSVR------TRLEQVHEWLAKKRLSFSSQELSDLQSEIQRLTYLVNLLMRCKMAEK--VKGSIAEEVSSIRNILEKTSKFTQEDEQLVQKKMDALKTTLPCSGLGISDEERVQIVTAMGVPRGHWFKCPNGHIYVITECGGAMQRSTCPECQEVIGGENHTLERSNHLASEMDGAQHPAWSNTANNFMNFEEIHRMM-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P2E3-1", "uniprot_id": "ZNFX1_HUMAN", "id": "Q9P2E3-1", "name": "NFX1-type zinc finger-containing protein 1", "aln": "MEERR--PHLDARPRNSHTNHRGPVDG----ELPPRARNQANNPPANALRGG-----------------ASHPGRHPRANNHPAAYWQREERFRAMGRNPHQGR-----------------RNQEGHASDEARDQRHDQENDTRW--------------------------------------RNGNQDCRNRRPPWSNDNFQQWRTPHQ-----------------KPTEQPQQAKKLGYKFLESLLQKDPSEVVITLATSLGLKELLSHSSMKSNFLELICQVLRKACSSKMDRQSVLHVLGILKNSKFLKVCLPAYVVGMITEPIPDIRNQYPEHISNIISLLQDLVSVFPASSVQETSMLVSLLPTSLNALRASGVDIEEETEKNLEKVQTIIEHLQEKRREGTLRVDTYTLVQPEAED--HVESYRTMPIYPTYNEVHLDERPFLRPNIISGKYDSTAIYLDTHFRLLREDFVRPLREGILELLQSFEDQG-----LRKRKFDDIRIYFDTRIITPMCSSSGIVYKVQFDTKPLKFVRWQNSKRLLYGSLVCMSK-DNFETFLFATVSNREQEDLCRGIVQLCFNEQSQQLLAEVQPSDSFLMVETTAYFEAYRHVLEGLQEVQEEDVPFQRNIVECNSHVKEPRYLLMGGR-YDFTPLIENPSATGEFLRNVEGLRHPRINVLDPGQWPSKEALKLDDSQMEALQFALTRELAIIQGPPGTGKTYVGLKIVQALLTNESVWQISLQKFPILVVCYTNHALDQFLEGIYNCQKTSIVRVGGRSNSEILKQFTLRELRNKREFRRNLPMHLRRAYMSIMTQMKESEQELHEGAKTLECTMRGVLREQYLQKYISPQHWESLMNGPVQDSEWICFQHWKHSMMLEWLGLGVGSFTQSVSPAGPENTAQAEGDEEEEGEEESSLIEIAEEADLIQADRVIEEEEVVRP-QRRKKEESGADQELAKMLLAMRLDHCGTG------TAAGQEQATG-EWQTQRNQKKKMKKRVKDELRKLNTMTAAEANEIEDVWQLDLSSRWQLYRLWLQLYQADTRRKILSYERQYRTSAERMAELRLQEDLHILKDAQVVGMTTTGAAKYRQILQKVEPRIVIVEEAAEVLEAHTIATLSKACQHLILIGDHQQLRPSANVYDLAKNFNLEVSLFERLVKVNIPFVRLNYQHRMCPEIARLLTPHIYQDLENHPSVLKYEKIKGVSSNLFFVEHNFPEQEIQEGKSHQNQHEAHFVVELCKYFLCQ-EYLPSQITILTTYTGQLFCLRKLMPAKTFAGVRVHVVDKYQGEENDIILLSLVRSNQEGKVGFLQISNRICVALSRAKKGMYCIGNMQMLAKVP--LWSKIIHTLRENNQIGPMLRLCCQNHPETHTLVSKASDFQKVPEGGCSLPCEFRLGCGHVCTRACHPYDSSHKEFQCMKPCQKVICQEGHRCPLVCFQECQPCQVKVPKTIPRCGHEQMVPCSVPESDFCCQEPCSKSLRCGHRCSHPCGEDCVQLCSEMVTIKLKCGHSQPVKCGHVEGLLYGGLLVKCTTKCGTILDCGHPCPGSCHSCFEGRFHERCQQPCKRLLICSHKCQEPCIGECPPCQRTCQNRCVHSQCKKKCGELCSPCVEPCVWRCQHYQCTKLCSEPCNRPPCYVPCTKLLVCGHPCIGLCGEPCPKKCRICHMDEVTQIFFGFEDEPDARFVQLEDCSHIFEVQALDRYMNEQKD-----DEVAIRLKVCPICQVPIRKNLRYGTSIKQRLEEIEIIKEKIQGSAGEIATSQERLKALLERKSLLHQLLPEDFLMLKEKLAQKNLSVKDLGLVENYISFYDHLASLWDSLKKMHVLEEKRVR------TRLEQVHEWLAKKRLSFTSQELSDLRSEIQRLTYLVNLLTRYKIAEKK-VKDSIAVEVYSVQNILEKTCKFTQEDEQLVQEKMEALKATLPCSGLGISEEERVQIVSAIGYPRGHWFKCRNGHIYVIGDCGGAMERGTCPDCKEVIGGTNHTLERSNQLASEMDGAQHAAWSDTANNLMNFEEIQGMM-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PND3-1", "uniprot_id": "A0A8M9PND3_DANRE", "id": "A0A8M9PND3-1", "name": "", "aln": "MANPRGGPQRGRGGFSVPPRRDGSVPGHRQASVSPNRRRGSGGRGEGGGGRGGGGGGGRGGGIGGGGRGSGQGGRGRGGGRGRGSGGERDGRGRGDRSHQHTGESTNSLWERWTDGITQSARGRDGRGQRKGENKQHHQGNAVHRPIIMGGATHLPSPYQGKFGRSLPGLMQLNLTPSSMQQPMNSRHDLEGMSLQRTSGGMSDLRASPQGEARTESQRGRGGHWRGRGRDGPPEVRTLGYKTLEGLLEKEASEVAITLSSSTGLRNLLEEKVMRNDLVQLVCQVLCKAFQSRIDRNTVMHLARVVKDSQFFLSILPHHVTGMMSDYMPARRDQYPQHLSNIISLVSDVLNMFPQSSVHSVSMLVTLLKPTINQLRASGVDVLANTDQDLERVQGLVNHLQEKSREGTLRSDKYSFLTADEDAPPGEEDFRMMSIYPSFEEFHLDQKPFLRPNIISQSFPNARIYLDTHFRLLREDFVRPLREGVKELLRIHHTEKTNGIPMKNRQFDDIRVYFDTRVILPLCTSMGIAYKVKFDTRRLQFVRWENSKRLLYGSLVCLSM-DNFETFLFATVTDRDPKLLRQGEVNLCFSPDSRAALARVQPSDSFLMVETTAYFEAYRYVLEGLQEQDENDVPFQRYIVECKTDVDPPAYLLVEGRSYDLSCIAAEGQGK-----------IPPFNPLTQNAWPDEEKMGLDESQLQALKLALTKELAIIQGPPGTGKTHVGLKIAQALLKNHEAWSN---GCPMLVVCYTNHALDQFLEGIHGFLKDGIVRVGGRSNSETLKRFGLRELTRFKDFRKNLPQHLRRAHHEISNNMQEAETLLKAQSAQLECSLRGVLKEDFLEKYISEQHWHSLCLQPLSDG-FETVGKKKPSMMAEWLGIGFSLFFQGPQQTDGEVAEDEDGAQLEEEE----LIDIDEEADLIQAERIVVDAEHGDKDKYKLKVEEKNIAAMAELMLALNLNDAEAQPGQNQTQTHGHAQADEQEWQMQGHQKKKLRQMARKELKKTSAMSEKEERRIRDVWSLSLKDRWKLYRLWVLRYRSDLRTKALASEQVYQEAAERLNEIRRHEDLSVLRQARVVGMTTTGAAKYRQALQQLQPRLVIVEEAAEVLEAHTITTLSKACQHLILIGDHQQLRPSATVYELAKNFSLEVSMFERLVRVNFPFVRLNYQHRMRPSIARLLTPHIYSSLENHPSVLKYDNVKGVLTNLFFVDHIQPEEEIKDGRSHQNPHEARFVVELCQYLLFQ-DYKPSQITILTTYTGQLHCLRKLMPSPKFSGVKVHVVDKYQGEENDIIILSLVRSNPQRRVGFLNIPNRVCVALSRAKMGLYCIGNMDMLSSVT--LWSNIIHTLREHDQVGPALTLSCQNHPDKQIHASCGNDFKGAPEGGCDQPCQYRLDCGHVCTRMCHPYDAEHKEYKCMKDCSKVLCELGHKCTRRCHQECGKCMVSVDKIIPSCQHNQKVPCHKDPAEFVCQVRCEKTLPCGHPCKATCGESCTSQCMVRVPIELKCGHMQEEPCFVSRDHKNE---PRCNTKCGTVLKCGHSCPGTCNGCHQGRLHKACTHKCQQILVCSHECREPCVRDCPPCSSRCQNRCVHSECKKTCGQSCAPCREPCAWQCPHHSCTKLCHEPCDRPPCSVPCNKTLTCGHRCIGLCGEPCPNKCRVCHKEEVTEIFFGSEDEPDACFIQLEDCKHLFEVTGMDQYMNLDEDQGAELDQRAIRLKDCPRCRTPIRRNLRYGTHINRSLAAIEMVKEKINGVPDIIKQQQDVLSLVLNDKTNLKKYLPDKFVSLQEKLDTNVLSIQQLWHLENLMNFLESVGKLKATQVKHESTILERLQKNQPFFRKTEEVLRFLLDPAQRFSEQQVADLGRELKRLSYLAELNERCRMSRFKSPEVVLGTEVQHLRGILEDTLPFSEGLERTVQQMFTKLDVILPRSGLGITEEERVMIVQAVGLNKGHWYKCPNGHVYAIGECGGAMEKTKCPECHAEIGGSNHALTQGNAVASEMDGAQHPAWSDAAN--MANFDLDNFED", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VCB7-1", "uniprot_id": "Q9VCB7_DROME", "id": "Q9VCB7-1", "name": "NFX1-type zinc finger-containing protein 1", "aln": "------------------------------------------------------------------------------MSSSDDDWFDQDENKLLQG------------------------LEKSLKSLELQKNEEYIECPPSER-----------------------------------------------KCPPS------------------------------EVGEYVMQHTRFSLTELTNALKMPAIDMFLYFLSDK--RDLFENQVLATDNVKRVGLFVDVLWS-----------LCELELGGFDEVFLSAFSR----------QTALLDKIKNLLQAKAAVAKCDAESALILSHSKWMLLRAHKHGLLSHQGYELVELYKKLAPSFKSDMIDGLEAFTGNFSHNVKGLIYPTLET--------LLGKDATKAPNEEEDEGLVSDKVVK--------YVNALRNLLREDFLAPLVEFVQQLRSGTDVDELK---QQGLLWSDVHLTLNPQFANAQRHSLVFLKVQFTKESKNAYKTWLNS--IKSGTLLCLTTSLAFDDLILASVGYTEPEKLKEDCLSVQIVKQYNIGNAYNRP---LIMFQAPVFFEPYLRVHNYLSTCSTEKFPMGRYIVDGQMEIPPPAYMKPGVK--------------------------LSFNMKPFTLDKLPEDLHLNESQKTAFKEALCREFSIIQGPPGTGKTHLSVQLVNSLIQNAKALGTG----PIIVLTYTNNSLDKFLVKIS-RYTQEILRFGNQSRDPQISKFNLSTTIKP----ELVPPRLKRIWWLVNCEYKEKFRNLQGLYANFDGSEE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SYQDTLAAQEKLNQVAERIETLRMVFQFFLAREKDLLAMTTTCAARHNFLFRLLQSKCVLFEEAAEIQEAHIVACLTPHTEHVILVGDHKQLQPFSGSRKVP-----QISLFERLIVAGLPFSRLNLQYRMRSCISELLVPSIYDELLCSESVKEYEDIRLMSKNLYFVQHNQPEHCMSD-MSIGNLYEAGVLAKLTEFLIQKAQYKHSDIVILSPYNGQIECIKNALPQNYRSTVQVASVDSFQGLEANIVLLSLVRSNISGRIGFLRQANRVCVALSRARWALYIVGNVTILKDTFPKIWNPIVKRLKENNAIGEAFPTITST-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ::: . :. : .::. : . . : . :. . * . *: . :: : : :. ::*:... : . :: : .: . :: . * *. . : :::.*::. : . . *:: ** . : * : : :.* : *.: : :: . : : .: . ::. :: :::. *::: .******: ** * : :* . : : :.*::: ::.:. . : : . * ** : *:*:*:: *: :::*:* : : * .. :.: : : . * :* ::*.::..:**.* * : *. . :..*: * **: . : * *: : :* * : *::** *:: ** :*::***********::.:::.::*: * .. *::*: ***::**:** * . *:*.*.:*.. :.:* * . . :* :*:* : : :* *: :: : . *: :. . ***: :* :: : :: ::.**** **::. :: ::.: *:.*****: *** :: *: :*:**:***:**:* : .:. ::*:****: ...** *** *:** . *:.**.* **..* ** :*:.:: : .**:**:* **. :.: * * :** .:.:* :::: : :* *:*.**:.*.**: *::: :* : ::* **.:** * ::::******* . ::***. .**:*******: .:* :**: :* .. :*. *:: *:*:. :* : .. ", "identical_positions": 200, "similar_positions": 324, "identity": "9.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110805-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70536-1", "uniprot_id": "OXYR_RAT", "id": "P70536-1", "name": "Oxytocin receptor", "aln": "------MEGTP--AANWSVELDLGSGVPPGEEG--------------------------------------------------------NRTAGPPQRNEA--------------------LARVEVAVLCLILFLALSGNACVLLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLR-RRTDRLAVLGTWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYVTWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAAEGNDAAGG-AGRAALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDVNAPKEASAFIIAML--LASLNSCCNPWIYMLFTGHLFHELVQR-----FFCCSARYLKGSRPGETSVSKKSNSSTFVLSRRSSSQRSCSQPSSA------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97926-1", "uniprot_id": "OXYR_MOUSE", "id": "P97926-1", "name": "Oxytocin receptor", "aln": "------MEGTP--AANWSIELDLGSGVPPGAEG--------------------------------------------------------NLTAGPPRRNEA--------------------LARVEVAVLCLILFLALSGNACVLLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLR-RRTDRLAVLATWLGCLVASVPQVHIFSLREVADGVFDCWAVFIQPWGPKAYVTWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAAEGSDAAGG-AGRAALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDVNAPKEASAFIIAML--LASLNSCCNPWIYMLFTGHLFHELVQR-----FLCCSARYLKGSRPGETSISKKSNSSTFVLSRRSSSQRSCSQPSSA------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30559-1", "uniprot_id": "OXYR_HUMAN", "id": "P30559-1", "name": "Oxytocin receptor", "aln": "------MEGAL--AANWSAEAANASAAPPGAEG--------------------------------------------------------NRTAGPPRRNEA--------------------LARVEVAVLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLR-RRTDRLAVLATWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDANAPKEASAFIIVML--LASLNSCCNPWIYMLFTGHLFHELVQR-----FLCCSASYLKGRRLGETSASKKSNSSSFVLSHRSSSQRSCSQPSTA------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E4W698-1", "uniprot_id": "OXYRB_DANRE", "id": "E4W698-1", "name": "Oxytocin receptor B", "aln": "------MESLLKDVILWPINDSWANSSRGNDSRG------------------------------------------------------LNQTVNPLKRNEE--------------------VAKVEVTVLVLILLLALAGNLCVLVAIQTSKHGQSRMYYFMKHLSIADLVVAVFQVLPQLIWDITFRFYGPDFLCRLVKYLQVVGMFASTYMLVLMSIDRCLAIWQPLRSLR-RRKDRFYVLASWIISLLFSLPQVYIFSLREVGDGVFDCWGDFVQPWGAKAYVTWISLTIYIIPVAILSVCYGLISYKIWQNFRLKTRRDQCLSLTPRPTKG----AALSRVSSVKLISKAKIRTVKMTFVIVMAYIICWTPFFFVQMWSAWDPMAPREAMAFIIAML--LASLNSCCNPWIYMFFAGHLFRDLMQR-----CLTVSHCGCKRHWR------NKNHSGTGAMRS-SSSQKSVTQSSTT------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q868T3-1", "uniprot_id": "CCAPR_DROME", "id": "Q868T3-1", "name": "Cardioacceleratory peptide receptor", "aln": "MLHLRLFDSSLYYTLASASESSGLASSTSTERSFNGTQGAGGVAAGGESLTPTDVAAVNLTYFTPAISHVMLAPTTIATTTASATMVQIQTTAAPSHDLETGGNSTSSDPGEFDNLNSFYFYETEQFAVLWILFTVIVLGNSAVLFVMFINKNRKSRMNYFIKQLALADLCVGLLNVLTDIIWRITISWRAGNLACKAIRFSQVCVTYSSTYVLVAMSIDRYDAITHPMNFSKSWKRARHLVAGAWLISALFSLPILVLYEEKLIQG-HPQCWIELGSPIAWQVYMSLVSATLFAIPALIISACYAIIVKTIWAKGSIFVPTERAGFG----------AAPARRASSRGIIPRAKVKTVKMTLTIVFVFIICWSPYIIFDLLQVFGQIPHSQTNIAIATFIQSLAPLNSAANPLIYCLFSSQVFRTLSRFPPFKWFTCCCKSYRNNSQQNRCHTVGRRLHNSCDSMRTLTTSLTVSRRSTNKTNARVVICERPTKVVTVPAMSEV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. . . : . : *. * : * :.:** ::: : : ** .**..: .:: :**: :*:*:*::*** *.:::**.:::* **: : . :: *: ::: ** ::***:*: **:** ** :*:. : : * * .:*: . : * * : ::. : : . :** : .* . :.*:: :: ::: :*. :::.**.:* .** : : . . .. *.** :*.:**::*****: **:.:*:**:*:::.:: ..:. . :: * .:: **.***..** ** :*:.::*: * : . : : .: ::. : :: *: ", "identical_positions": 83, "similar_positions": 149, "identity": "16.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110805-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70536-1", "uniprot_id": "OXYR_RAT", "id": "P70536-1", "name": "Oxytocin receptor", "aln": "----------------------------------------------------------------------------MEGTPAAN--WSVELDLGSGVPPGEEGNRTAGPPQRNE------ALARVEVAVLCLILFLALSGNACVLLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRT-DRLAVLGTWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYVTWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAAEGNDAAGG-AGRAALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDVNAPKEASAFIIAML--LASLNSCCNPWIYMLFTGHLFHELVQR-----FFCCSARYLKGS----------RPGETSVSKKSNSSTFVLSRRSSSQR-----SCSQPSSA---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97926-1", "uniprot_id": "OXYR_MOUSE", "id": "P97926-1", "name": "Oxytocin receptor", "aln": "----------------------------------------------------------------------------MEGTPAAN--WSIELDLGSGVPPGAEGNLTAGPPRRNE------ALARVEVAVLCLILFLALSGNACVLLALRTTRHKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRT-DRLAVLATWLGCLVASVPQVHIFSLREVADGVFDCWAVFIQPWGPKAYVTWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAAEGSDAAGG-AGRAALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDVNAPKEASAFIIAML--LASLNSCCNPWIYMLFTGHLFHELVQR-----FLCCSARYLKGS----------RPGETSISKKSNSSTFVLSRRSSSQR-----SCSQPSSA---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30559-1", "uniprot_id": "OXYR_HUMAN", "id": "P30559-1", "name": "Oxytocin receptor", "aln": "----------------------------------------------------------------------------MEGALAAN--WSAEAANASAAPPGAEGNRTAGPPRRNE------ALARVEVAVLCLILLLALSGNACVLLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQVVGMFASTYLLLLMSLDRCLAICQPLRSLRRRT-DRLAVLATWLGCLVASAPQVHIFSLREVADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAAAEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVWDANAPKEASAFIIVML--LASLNSCCNPWIYMLFTGHLFHELVQR-----FLCCSASYLKGR----------RLGETSASKKSNSSSFVLSHRSSSQR-----SCSQPSTA---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E4W699-1", "uniprot_id": "OXYRA_DANRE", "id": "E4W699-1", "name": "Oxytocin receptor A", "aln": "----------------------------------------------------------------------------MEDIFKDQDFWSFNESSRNATNETYGVNQTVNPLKRNE------EVAKVEVTVLALVLFLALAGNLCVLIAIHTAKHSQSRMYYFMKHLSIADLVVAVFQVLPQLIWDITFRFYGPDILCRLVKYLQTVGMFASTYMLVLMSIDRCMAICQPLRSLHKRK-DRCYVICSWALSLLFSIPQVYIFSLREVGSGVYDCWGDFVQPWGAKAYITWISLTIYIIPVTILSVCYGLISFKIWQNFKRKTKRDQCITLTPKASKG----NALARVSSVKLISKAKITTVKMTFVIVLAYIVCWTPFFSVQMWSAWDPEAPREAMPFIISML--LASLNSCCNPWIYMFFAGHLFHDLKQN-----LFCCSTLYLKSSQ--------CRYDPEQDSRKSNSSTYVIKS-TSSQR-----SITQTSIT---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q868T3-1", "uniprot_id": "CCAPR_DROME", "id": "Q868T3-1", "name": "Cardioacceleratory peptide receptor", "aln": "MLHLRLFDSSLYYTLASASESSGLASSTSTERSFNGTQGAGGVAAGGESLTPTDVAAVNLTYFTPAISHVMLAPTTIATTTASATMVQIQTTAAPSHDLETGGNSTSSDPGEFDNLNSFYFYETEQFAVLWILFTVIVLGNSAVLFVMFINKNRKSRMNYFIKQLALADLCVGLLNVLTDIIWRITISWRAGNLACKAIRFSQVCVTYSSTYVLVAMSIDRYDAITHPMNFSKSWKRARHLVAGAWLISALFSLPILVLYEEKLIQG-HPQCWIELGSPIAWQVYMSLVSATLFAIPALIISACYAIIVKTIWAKG-------SIFVPTERAGFG---AAPARRASSRGIIPRAKVKTVKMTLTIVFVFIICWSPYIIFDLLQVFGQIPHSQTNIAIATFIQSLAPLNSAANPLIYCLFSSQVFRTLSRFPPFKWFTCCCKSYRNNSQQNRCHTVGRRLHNSCDSMRTLTTSLTVSRRSTNKTNARVVICERPTKVVTVPAMSEV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . * * . . : :.:** ::: : : ** .**:.: :: :**: :*:*:*::*** *.:::**.:::* **: : . :: *: ::: *. ::***:*: **:** ** :*:. : . * * :* . : * * : ::. : : . :** : .* . :.*:: :: ::: :*. :::.**.:* .** : *. * . *.** :*.:**: *****: **:.:*:**:*:: .:: ..:. . :: * :: **.***..** ** :*:.::*: * : : **. * :. * * :: ::: .:. ::.: :.: . ", "identical_positions": 87, "similar_positions": 146, "identity": "17.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110805-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q569C0-1", "uniprot_id": "TM100_RAT", "id": "Q569C0-1", "name": "Transmembrane protein 100", "aln": "-----------MTEEPTKENLGGPKSPTPVTMEKS----PKSEVVVTTVPLVSEVQLTAATGGAELSCYRCIIPFAVVVFITGIVVTAVAYSFNSHGSVISILGLVLLSSGLFLLASSALCWKVRQRNKKVKRRESQTALVVNQRSLFA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQG9-1", "uniprot_id": "TM100_MOUSE", "id": "Q9CQG9-1", "name": "Transmembrane protein 100", "aln": "-----------MTEESTKENLGAPKSPTPVTMEKN----PKREVVVTTGPLVSEVQLMAATGGAELSCYRCIIPFAVVVFITGIVVTAVAYSFNSHGSIISIFGLVLLSSGLFLLASSALCWKVRQRNKKVKRRESQTALVVNQRCLFA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NV29-1", "uniprot_id": "TM100_HUMAN", "id": "Q9NV29-1", "name": "Transmembrane protein 100", "aln": "-----------MTEEPIKEILGAPKAHMAATMEKS----PKSEVVITTVPLVSEIQLMAATGGTELSCYRCIIPFAVVVFIAGIVVTAVAYSFNSHGSIISIFGLVVLSSGLFLLASSALCWKVRQRSKKAKRRESQTALVANQRSLFA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RS32-1", "uniprot_id": "A0A8M1RS32_DANRE", "id": "A0A8M1RS32-1", "name": "", "aln": "MPQNTLPLDPAMPTELLKDTMTIPGAPERILAEKTNNNEPQAQAPAVIIPLVNEVQLTAATGGAELSCYRCTVPFGVVVLIAGIVVTVVAYTFNSHGSTISYFGLVLLSAGLVLLALSAVCWKVRMERKKERRRESQTALMAHQRSIFA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * *: : * : **. *: :. . ***.*:** *****:******* :**.***:*:*****.***:****** ** :***:**:**.*** **:***** . ** :********:.:**.:**", "identical_positions": 78, "similar_positions": 30, "identity": "52.35%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110810-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86XK2-1", "uniprot_id": "FBX11_HUMAN", "id": "Q86XK2-1", "name": "F-box only protein 11", "aln": "-----MNSVRAANRRPRR--------VSRPR-----PVQQQQQQPPQQPPPQPPQQQPPQQQP-----------------------------------------------------------------------PPPPQQQQ----QQQPPPPPPPPPPLPQERNNVG-----ERDDDVPADMVAEESGPGAQNSPYQLRRKT-------------------------------LLPKRTACPTKNSMEGASTSTTENFG---------------------------------------------------------------HRAKRARVSGKSQDLSAAP--------------------AEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPEPGKFYQINPEEYEHPNPWKESFQQLYKGAHVKPGFAEHFYSN--------------------------PARYKGR---ENMLYYDTIEDALGG--------------VQEAHFDGLIFVHSGIYTDEWIYIESPITMIGAAPGKVADKVIIENTRDSTFVFMEGSEDAYVGYMTIRFNPDDKSAQHHNAHHCLEITVNCSPIIDHCIIRSTCTVGSAVCVSGQGACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRRNKIHDGRDGGICIFNGGRGLLEENDIFRNAQAGVLISTNSHPILRKNRIFDGFAAGIEITNHATATLEGNQIFNNRFGGLFLASGVNVTMKDNKIMNNQDAIEKAVSRGQCLYKISSYTSYPMHDFYRCHTCNTTDRNAICVNCIKKCHQGHDVEFIRHDRFFCDCGAGTLSNPCTLAGEPTHDTDTLYDSAPPIESNTLQHN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TPD1-1", "uniprot_id": "FBX11_MOUSE", "id": "Q7TPD1-1", "name": "F-box only protein 11", "aln": "-----MNSVRAANRRPRR--------VSRPR-----PVQQQQQQPPQQPPPQPPQQQPPPQPP-----------------------------------------------------------------------QQPPQQQPPPPPQQQPPPPPPPPPPPPQDRNNAG-----ERDD-VPADMVAEESGPGAQNSPYQLRRKT-------------------------------LLPKRTACPTKSSMEGASTSTTENFG---------------------------------------------------------------HRAKRARVSGKSQDLSAAP--------------------AEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPEPGKFYQINPEEYEHPNPWKESFQQLYKGAHVKPGFAEHFYSN--------------------------PARYKGR---ENMLYYDTIEDALGG--------------VQEAHFDGLIFVHSGIYTDEWIYIESPITMIGAAPGKVADKVIIENTRDSTFVFMEGSEDAYVGYMTIRFNPDDKSAQHHNAHHCLEITVNCSPIIDHCIIRSTCTVGSAVCVSGQGACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRRNKIHDGRDGGICIFNGGRGLLEENDIFRNAQAGVLISTNSHPVLRKNRIFDGFAAGIEITNHATATLEGNQIFNNRFGGLFLASGVNVTMKDNKIMNNQDAIEKAVSRGQCLYKISSYTSYPMHDFYRCHTCNTTDRNAICVNCIKKCHQGHDVEFIRHDRFFCDCGAGTLSNPCTLAGEPTHDTDTLYDSAPPIESNTLQHN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TSL3-1", "uniprot_id": "FBX11_RAT", "id": "Q7TSL3-1", "name": "F-box only protein 11", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVAEESGPGAQNSPYQLRRKT-------------------------------LLPKRTACPTKNSMEGASTSTTENFG---------------------------------------------------------------HRAKRARVSGKSQDLSAAP--------------------AEQYLQEKLPDEVVLKIFSYLLEQDLCRAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPEPGKFYQINPEEYEHPNPWKESFQQLYKGAHVKPGFAEHFYSN--------------------------PARYKGR---ENMLYYDTIEDALGG--------------VQEAHFDGLIFVHSGIYTDEWIYIESPITMIGAAPGKVADKVIIENTRDSTFVFMEGSEDAYVGYMTIRFNPDDKSAQHHNAHHCLEITVNCSPIIDHCIIRSTCTVGSAVCVSGQGACPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNSIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGCIEDNEIFDNAMAGVWIKTDSNPTLRRNKIHDGRDGGICIFNGGRGLLEENDIFRNAQAGVLISTNSHPVLRKNRIFDGFAAGIEITNHATATLEGNQIFNNRFGGLFLASGVNVTMKDNKIMNNQDAIEKAVSRGQCLYKISSYTSYPMHDFYRCHTCNTTDRNAICVNCIKKCHQGHDVEFIRHDRFFCDCGAGTLSNPCTLAGEPTHDTDTLYDSAPPIESNTLQHN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9QEP9-1", "uniprot_id": "A0A8M9QEP9_DANRE", "id": "A0A8M9QEP9-1", "name": "F-box only protein 11", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVAEESGPGAQNSPYQLRRKS-------------------------------LLPKRTVCPTKNSMEGASTSATENFG---------------------------------------------------------------HRAKRARVSGKSQDLPAAP--------------------AEQYLQEKLPDEVVLKIFSYLLEQDLCQAACVCKRFSELANDPILWKRLYMEVFEYTRPMMHPEPGKFYQINPEEYEQPNPWKESFQQLYKGAHVKPGFAEHFYSN--------------------------PARYKGR---ENMLYYDTIEDALGG--------------VQEAHFDGLIFVHSGIYTDEWIYIESPITMIGAASGKVADKVVIENTRDSTFVFMEGSEDAYVGYMTIRFNPDDKSAQHHNAHHCLEITVNCSPNIDHCVIRSTCTVGSAVCVSGQGAGPTIKHCNISDCENVGLYITDHAQGIYEDNEISNNALAGIWVKNHGNPIIRRNHIHHGRDVGVFTFDHGMGYFESCNIHRNRIAGFEVKAYANPTVVRCEIHHGQTGGIYVHEKGRGQFIENKIYANNFAGVWITSNSDPTIRGNAIFNGNQGGVYIFGDGRGLIEGNDIYGNALAGIQIRTNSCPIVRHNKIHDGQHGGIYVHEKGQGVIEENEVYSNTLAGVWVTTGSTPVLRRNRIHSGKQVGVYFYDNGHGVLEDNDIYNHMYSGVQIRTGSNPKIRRNKIWGGQNGGILVYNSGLGFIEDNEIFDNAMAGVWIKTDSNPTLRRNKIHDGRDGGICIFNGGRGLLEENDIFRNAQAGVLISTNSHPVLRKNRIFDGFAAGIEITNHATATLEGNQIFNNRFGGLFLASGVNVTMKDNKIMNNQDAIEKAVSRGQCLYKISSYTSYPMHDFYRCHTCNTTDRNAICVNCIKKCHQGHDVEFIRHDRFFCDCGAGTLSNPCTLAGEPTHDTDTLYDSAPPIESNTLQHN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VH60-1", "uniprot_id": "Q9VH60_DROME", "id": "Q9VH60-1", "name": "F-box only protein 11", "aln": "MPSASFTSSRTYVRRSRRKGANRIAMPNRPTGNIMDPMLQQNVTAAGAGASASGSNSNAASSSGAGGVGNNNASSSGSSGATSTSGSAAAAASAAGPTAAGASSSAEYFDSGQGASGSSGAASSGFSGSFYNALQMMDTTESSGAGTSQSTPPALGASSTTASKSTCATVGSSTASTSAAAAAAASASAGSSHQSPYDLRRKISASSHEQWPTSSSSAVAAAAAILVGPSSSSPPLVNPGASPSSSSSSSSSSSSSSSASSSSSSSNVQAPSTSATFPVNNAPTTGATLAQPPNVHSSVPQQHCGALPVGAAIEDNNYMLPARKRSRRLYTQGGEMGPSAGATGEAAGAGTAASGGAGCAPTAAQYLQYELPDEVLLAIFSYLMEQDLCRLALVCKRFNTIANDTELWKRLYQSVFEYDLPLFNPELCKFVFEKPEESEYANPWKESFRQLYRGVHVRPGYQERRSSGRSIVFFNTIQAALDYPEERAAAGVFVPAGAGAGNVVSAGLSNTSASAGVGGASVNALVNIYEEQVAPTEHPGPLIFLHAGHYKGEYLFIDSDVALVGAAPGNVAESVILEREAGSTVMFVEGAKYAYVGYLTLKFSPEVTSTVSHHKHYCLDIGENCSPTVDNCIIRSTSVVGAAVCVGGVNANPVIRNCDISDCENVGLYVTDYAQGTYEHNEISRNALAGIWVKNFASPIMRENHIHHGRDVGIFTFENGMGYFEKNDIHNNRIAGFEVKAGANPTVVKCEIHHGQTGGIYVHENGLGQFIENRIHSNNFAGVWITSNSNPTIRKNEIYNGHQGGVYIFGEGRGLIEHNNIYGNALAGIQIRTNSDPIVRHNKIHHGQHGGIYVHEKGQGLIEENEVYSNTLAGVWITTGSTPVLRRNRIHSGKQVGVYFYDNGHGKLEDNDIFNHLYSGVQIRTGSNPVIRGNKIWGGQNGGVLVYNGGLGLLEQNEIFDNAMAGVWIKTDSNPTLKRNKIYDGRDGGICIFNGGKGILEENDIFRNTQAGVLISTQSHPILRRNRIYDGQAAGVEITNNATATLEHNQIFKNKFGGLCLASGVQPITRGNNIFNNEDEVEKAVSSGQCLYKISSYTSFPMHDFYRCQTCNTTDRNAICVNCIKNCHAGHDVEFIRHDRFFCDCGAGTLSNQCQLQGEPTQDTDTLYDSAAPMESHTLMVN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .*. *. .:::***:**** * : ..*:..* ..:*:*::.. . :*::* ..* . . .*.. * **** :*****:* *****:*****: * *****. :***. ****** .**** *:::** ** :*** * .*******:***:*.**:**: *: *. ** . . * : . .:** . * . ***:*:* *..*:::*:* ::::***.*:**:.*::*. .**.:*:**:: *****:*::*.*: .*: *: *:**:* **** :*:*:****..**:****.* .* *.*::*:**********:**:*** **.****.**********...**:*.**********:***::******. :**.********** ******:***************:* ******:*::************:**** * *:**:********:****** *:*************** *********.**************:***************:***************************** ******:**:************ ** **********:****.*** :*:*********************:****:*************:*:*********:********:***:**:***:** ***:****:****** ****:*:**** *****: :.*:*:**:* :***** ************:********:****************:** *********************** * * ****:*********.*:**:** *", "identical_positions": 583, "similar_positions": 169, "identity": "49.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110815-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7Z3F1-1", "uniprot_id": "LYCHS_HUMAN", "id": "Q7Z3F1-1", "name": "Lysosomal cholesterol signaling protein", "aln": "MNSNLPAENLTIAVNMTKTLPTAVTHGFNSTNDPPSMSITRLFPALLECFGIVLCGYIAGRANVITSTQAKGLGNFVSRFALPALLFKNMVVLNFSNVDWSFLYSILIAKASVFFIVCVLTLLVASPDSRFSKAGLFPIFATQSNDFALGYPIVEALYQTTYPEYLQYIYLVAPISLMMLNPIGFIFCEIQKWKDTQNASQNKIKIVGLGLLRVLQNPIVFMVFIGIAFNFILDRKVPVYVENFLDGLGNSFSGSALFYLGLTMVGKIKRLKKSAFVVLILLITAKLLVLPLLCREMVELLDKGDS-VVNHTSLSNYAFLYGVFPVAPGVAIFATQFNMEVEIITSGMVISTFVSAPIMYVSAWLLTFPTMDPKPLAYAIQNVSFDISIVSLISLIWSLAILLLSKKYKQLPHMLTTNLLIAQSIVCAGMMIWNFVKEK-NFVGQILVFVLLYSSLYSTYLWTGLLAISLFLLKKRERVQIPVGIIIISGWGIPALLVGVLLITGKHNGDSIDSAFFYGKEQMITTAVTLFCSILIAGISLMCMNQTAQAG-SYEGFDQSQSHKVVEPGNTAFEESPAPVNEPELFTSSIPETSCCSCSMGNGELHCPSIEPIANTSTSEPVIPSFEKNNHCVSRCNSQSCILAQEEEQYLQSGDQQLTRHVLLCLLLIIGLFANLSSCLWWLFNQEPGRLYVELQFFCAVFNFGQGFISFGIFGLDKHLIILPFKRRLEFLWNNKDTAENRDSPVSEEIKMTCQQFIHYHRDLCIRNIVKERRCGAKTSAGTFCGCDLVSWLIEVGLASDRGEAVIYGDRLVQGGVIQHITNEYEFRDEYLFYRFLQKSPEQSPPAINANTLQQERYKEIEHSSPPSHSPKT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JTJ7-1", "uniprot_id": "A0AC58JTJ7_DANRE", "id": "A0AC58JTJ7-1", "name": "", "aln": "------MEGLYVSIHGLN-----VTH---SPLGAPAMSIDKLFPALLECFGIILCGYAAGRSGIISAAQVNGLGSFVSCFALPALLFKNMVQLQFQHVVWSFLWSVLIAKVCVFTLVCVLTLLVADPESKYSKAGLFAIFATQSNDFALGYPIVDALYRNSHSEYEQYIYLVAPVSLMLLNPVGFALCEIQRWRHSSDPNYSKLHVIFTVTLQVLKNPIVFMVMVGIVSHFVFGGRVPVLLGEFVDGLADSFGGAALFYLGLNMVGQMSKLTRSTGVSLILLITAKLLVMPLMCRDMVELLDAGNSSSANHSSLSDYAFLYGVFPTAPSVAIYAAQYNMELEVVTSGMVISTFLSAPIMYVSAWLLTIPWMEASFLVKELQDVSFNISIVCLIALVWTLAVMLLSKKFRRMPHMFATNLFLAQLLACMSMLFWKFVLKQGSVFGQILTFTLLYGSLYSTYVWTGLLAFSLTLLGRNENLKVKPIVFIIFGWGIPFLTVGGLLMIGQRMSDSLDPAFFYGSGQIVSTVVVLGFSIVLGGLSLMGLSRGAQEEQSYQALDQNSITGASENSRHLQTENQNSSDVDQTHTN---TDVCCSEPMP---------DMIAGHLNDSPVPSAG------IVLGESSSSLRVQEE--------RQIARHVLLCLLLIVSMLANLSSCLWWLFSADPGRLYLELQFFCAVANYGQGFVSFGIFGLDEHLIILPFRKRLAALCGFSQEENLEPSAVPEEIRLTCTQFVRYHKDQCVQDIVRNRGMRAP---------------------------IAYGPTFVDYSGLLTCDKNMFVRNIFTQELFVSGNVEIQ----------------ICCTSPCKKDSWC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.* :::: : *** *. ..*:*** :***********:**** ***:.:*:::*.:***.*** ************ *:*.:* ****:*:****..** :*********.*:*::******.****************:***:.::.** ********:***:***:** :****:*:.:.:.. .*:::: *:**:*******::**. :*::. :*** : :*:***.:**.*:*******.***::.:*.:*: * ***********:**:**:****** *:* .**:***:*********.**.***:*:*:***:*::*********:*************:* *:.. *. :*:***:****.**:*:*:**::*****::::***::***::** :.* .*::*:** :: ...****.*.***.******:******:** ** :.*.::: ::** ***** * ** **: *:: .**:*.*****. *:::*.*.* **::.*:*** :.: ** **:.:**.. . * .. *. . : : .*. *** .* : **. ...** .: : :*.*.: .*** :*::**********:.::***********. :*****:******** *:****:********:*******::** * . .: : . *.*.***::** **::**:* *:::**::* * : ** :*: . : :: .*: : *:. . * . * :** .:.. ", "identical_positions": 425, "similar_positions": 242, "identity": "48.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110815-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A0B6-1", "uniprot_id": "A0A8I6A0B6_RAT", "id": "A0A8I6A0B6-1", "name": "", "aln": "------------------------------------------------MTAPEKPVKQEEMAALDVD------SGGGGGGHGEYLQQQ-------------------QQQQQHGNGAAAAAAAQDTQPSPLALLAATCSKIGPPS----------PGDDEEEA--AAAAG-------VPAAAAGATGDLASAQLGGAPNRWEVLSATPTTIKDEAGNLVQIPGAATSSGQYVLPLQNLQNQ-QIFSVAPGSD-----SSNGTVSNVQYQVIPQIQSTDAQQVQIGFTGSSDNGGINQESSQIQIIPGSNQTLLASGTPPANIQNLIPQT-------GQVQ-VQGVAIGGSSFPG----QTQVVANVPLGLPGNITFVPIN---SVDLDSLGLSGSSQTMTAGINADGHLINTGQAMDSSDNSERTGERVSPDVNETNADTDLFVPTSSSSQ---LPVTIDSTGILQQNTNSLTTTSGQVHSSDLQGNYIQSPVSEETQAQNIQVSTAQPVVQHLQLQDSQQPTSQAQIVQGITPQTIHGVQASGQNISQQALQNLQLQLNPGTFLIQAQTVTPSGQITWQTFQVQGVQNLQNLQIQNT---AAQQITLTPVQTLTLGQVAAGGALTSTPVSLSTGQLPNLQTVTVNSIDSTGIQLHPGENADSPADIRIKEEEPDPEEWQLSGDSTLNTNDLTHLRVQVVDEEGDQQHQEG----------KRLRRVACTCPNCKEGGGRGTNLGKKKQHICHIPGCGKVYGKTSHLRAHLRWHSGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKKFVCPECSKRFMRSDHLAKHIKTHQNKK-------------------------------------VIHSSSTVLASVEAGRDDALITAGGTTLILANIQQGSVSGIGTVNASATSNQDILTNTEIPLQLVTVSGNETME------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70494-1", "uniprot_id": "SP3_MOUSE", "id": "O70494-1", "name": "Transcription factor Sp3", "aln": "------------------------------------------------MTAPEKPVKQEEMAALDVD------GGGGGGGHGEYLQQQ-------------------QQQQQQHGNGAAAAAAQDTQPSPLALLAATCSKIGPPS----------PGDDDEEAAVAAAAG-------VPAAAAGATGDLASAQLGGAPNRWEVLSATPTTIKDEAGNLVQIPGAATSSGQYVLPLQNLQNQ-QIFSVAPGSD-----SSNGTVSNVQYQVIPQIQSTDAQQVQIGFTGSSDNGGINQENSQIQIIPGSNQTLLASGTPPANIQNLIPQT-------GQVQ-VQGVAIGGSSFPG----QTQVVANVPLGLPGNITFVPIN---SVDLDSLGLSGSSQTMTAGINADGHLINTGQAMDSSDNSERTGERVSPDVNETNADTDLFVPTSSSSQ---LPVTIDSTGILQQNTNSLTTTSGQVHSSDLQGNYIQSPVSEETQAQNIQVSTAQPVVQHLQLQDSQQPTSQAQIVQGITPQTIHGVQASGQNISQQALQNLQLQLNPGTFLIQAQTVTPSGQITWQTFQVQGVQNLQNLQIQNT---AAQQITLTPVQTLTLGQVAAGGALTSTPVSLSTGQLPNLQTVTVNSIDSTGIQLHPGENADSPADIRIKEEEPDPEEWQLSGDSTLNTNDLTHLRVQVVDEEGDQQHQEG----------KRLRRVACTCPNCKEGGGRGTNLGKKKQHICHIPGCGKVYGKTSHLRAHLRWHSGERPFICNWMFCGKRFTRSDELQRHRRTHTGEKKFVCPECSKRFMRSDHLAKHIKTHQNKK-------------------------------------VIHSSSTVLASVEAGRDDALITAGGTTLILANIQQGSVSGIGTVNTSATSNQDILTNTEIPLQLVTVSGNETME------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q02447-1", "uniprot_id": "SP3_HUMAN", "id": "Q02447-1", "name": "Transcription factor Sp3", "aln": "------------------------------------------------MTAPEKPVKQEEMAALDVDSG---GGGGGGGGHGEYLQQQ-------------------QQHG--NGAVAAAAAAQDTQPSPLALLAATCSKIGPPS----------PGDDEEEA--AAAAG-------APAAAG-ATGDLASAQLGGAPNRWEVLSATPTTIKDEAGNLVQIPSAATSSGQYVLPLQNLQNQ-QIFSVAPGSD-----SSNGTVSSVQYQVIPQIQSADGQQVQIGFTGSSDNGGINQESSQIQIIPGSNQTLLASGTPSANIQNLIPQT-------GQVQ-VQGVAIGGSSFPG----QTQVVANVPLGLPGNITFVPIN---SVDLDSLGLSGSSQTMTAGINADGHLINTGQAMDSSDNSERTGERVSPDINETNTDTDLFVPTSSSSQ---LPVTIDSTGILQQNTNSLTTSSGQVHSSDLQGNYIQSPVSEETQAQNIQVSTAQPVVQHLQLQESQQPTSQAQIVQGITPQTIHGVQASGQNISQQALQNLQLQLNPGTFLIQAQTVTPSGQVTWQTFQVQGVQNLQNLQIQNT---AAQQITLTPVQTLTLGQVAAGGAFTSTPVSLSTGQLPNLQTVTVNSIDSAGIQLHPGENADSPADIRIKEEEPDPEEWQLSGDSTLNTNDLTHLRVQVVDEEGDQQHQEG----------KRLRRVACTCPNCKEGGGRGTNLGKKKQHICHIPGCGKVYGKTSHLRAHLRWHSGERPFVCNWMYCGKRFTRSDELQRHRRTHTGEKKFVCPECSKRFMRSDHLAKHIKTHQNKK-------------------------------------GIHSSSTVLASVEAARDDTLITAGGTTLILANIQQGSVSGIGTVNTSATSNQDILTNTEIPLQLVTVSGNETME------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BD33-1", "uniprot_id": "A0A8M2BD33_DANRE", "id": "A0A8M2BD33-1", "name": "", "aln": "-------MPPRITRRCAVPSCGKTQSLHGLPSDPNLRKQWVNFIF---NEVPDRIIKSLFVCSLHFTTDSFTNKTQFDAGFSERLKVKDDAVPTILDPKVMQPQRSSHKTSREMGCQTEELNTQDGQCQTFPDLKPHTLKLEPRSET-----PEQPAKQQEMAALDVDSSQSDFLQPASGAQDQQTTDLTAIQMTGSSDRWEVLTPVSSVKGEPAVVHVPSGGLLGSNGQYVVPLQTMAGQTQPVFVTAGVD-----GTG--ANGVQYQVIPQLQGADG--ASLSYTASAADG--STLGTDIAILPDGTQG-IATATNANDLQGLLSQS-------GHVQQIPTVSLAGSGFGT----QGQVVAN--MGLPGNITLVPINSLSNVDLESLGLAG-AQTIATSVTADGQLIMTGPTTTTSDNQGESGK-CTESLNANDANANAFVPTTTSSTSTSLPETIDGTGVLTQAT---AVSAGHQDLSYIQQN---------------------------------HTTGGEQVVQLLPAQTADG--------AAQTLQSVQL-LNAGTFLIQAQTVSPTGQIQWQTFQVQGVQNLQNLQLPAAGGVSSPQITLAPVQTLSLGQSGTTGAL---------GQIPNLQTVTVNSVG----QYQQDENTESHTDIQIKEE-PESDDWPN---STLSTSDLAHLRVRLVEEDMEGTGQEG----------KRLRRVACTCPNCKEAGGRGSSMGKKKQHICHIPGCGKVYGKTSHLRAHLRWHSGERPFICSWSYCGKRFTRSDELQRHRRTHTGEKKFVCPECSKRFMRSDHLAKHIKTHQNKK-------------------------------------GLNSNTGVGQTEAAAPSDTIITGGGATVILANLQQAGT-------------QDLLSNSDLPLQLVTVSASEVLE------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHC8-1", "uniprot_id": "A0A0B4KHC8_DROME", "id": "A0A0B4KHC8-1", "name": "", "aln": "MLQYKSAASAATSAPPATPLAAGGSSKATIPPNGASAAASQTQVHGAPGTPTMQQIINIHQMPPQFAGGAVAGNGQNAGMPQNMFQIVQPMPMQTVNIDGQEAIFIPNLNAQLATAQAVNFNGQQAFITPNGQILRAPQMAANPAASNCIQLQQLNGLGQEQTQLITIPGTNIQIPVTNLIQQQQQAQQVHQGTVQQQAQGTNASGANGSGVTNSGTAGQLPGSITIPGTNLQIPTSVAAANGLLGNISNISNLLGGGQSIKLENGQLQMRPQLVQFPAPAMPQQQQTVAVQIPVQTANG-QTIYQTVHVPVQAAATSSGGLQNLMQAQSLQMPSASQMQIIPQFSQIAQIVTPNGQIQQVQLAMPYPQLPPNANIIHIQNPHQQQQQQVQQQQQQQQAQQQQQAQQQQAQQQQQQQVQAQHQQLLQAISDASAGGQLPPNQPITITNAQG---QQLTVIPAQLRPNAPTAPTPAPAGVPTPMQMPNLQALPIQNIPGLGQVQIIHANQLPPNLPANFQQVLTQLPMSHPQVQTQGQVQVMPKQEPQSPTQMITSIKQEPPDTFGPISATGNPPAPASTPNTASPQQQQIKFLHTESNS--LSSLSIPASIQITALPQQATNTPNTPATTQPIPVSLPARSKVNAVTTSSTQITIAPTGGQVVSVTTQARGATASIR-STNTSTTTITTPSQSHLNMNISVASVGGAATGGGGGTATGEPKPRLKRVACTCPNCTDGEKHSD---KKRQHICHITGCHKVYGKTSHLRAHLRWHTGERPFVCSWAFCGKRFTRSDELQRHRRTHTGEKRFQCQECNKKFMRSDHLSKHIKTHFKSRSGVELIELSIKQETKGGNAPKSISTVNGIVTIEIPGGGSAAAGSGASSVAATVAGSTVTPGGATIVQLPTVEASGGGDSFGDDEDDEEDDELTEEDDEDEELDEDDMDDCEDEEDDEDPELDSGDEVKMTIAVSEPGDNSSNXHSESLFMEQFLFDHFP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . . .. . : :: : : *: . : : . :* : . .. . : . : : . : . * : .: . .. . . . .. * *: **: . : : . . * *:.* . .:*.*: .::* : .: .. . * :* ** * .:: *: . : :.: * *: : . : . : : : .: :. :.:. *: : : : . : :.. . * * : .* : : . ..** : * .*.. . *::: *: : :.:* :* * .: . .:* ..*.. : . . . : : .. :*:.* . :**.:.: . * **:*********.:. :. **:******.** ****************:*****:*.* :**********************:* * **.*:*******:****** :.: : : * .: :* **:*:: :.. :* *:: : : : . : * ", "identical_positions": 133, "similar_positions": 187, "identity": "13.37%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110815-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8WVF1-1", "uniprot_id": "OSCP1_HUMAN", "id": "Q8WVF1-1", "name": "Protein OSCP1", "aln": "MSVRTLPLLFLNLGGEMLYILDQRLRAQNIPGDKARKDEWTEVDRKRVLNDIISTMFNRKFMEELFKPQELYSKKALRTVYERLAHASIMKLNQASMDKLYDLMTMAFKYQVLLCPRPKDVLLVTFNHLDTIKGFIRDSPTILQQVDETLRQLTEIYGGLSAGEFQLIRQTLLIFFQDLHIRVSMFLKDKVQNNNGRFVLPVSGPVPWGTEVPGLIRMFNNKGEEVKRIEFKHGGNYVPAPKEGSFELYGDRVLKLGTNMYSVNQPVETHVSGSSKNLASWTQESIAPNPLAKEELNFLARLMGGMEIKKPSGPEPGFRLNLFTTDEEEEQAALTRPEELSYEVINIQATQDQQRSEELARIMGEFEIT-EQPRLSTSKGDDLLAMMDEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BHW2-1", "uniprot_id": "OSCP1_MOUSE", "id": "Q8BHW2-1", "name": "Protein OSCP1", "aln": "MSVRTLPLLFLNLGGEMLYVLDQRLRAQNIPGDKARK----------VLNDIISTMFNRKFMDELFKPQELYSKKALRTVYDRLAHASIMRLNQASMDKLYDLMTMAFKYQVLLCPRPKDVLLVTFNHLDAIKGFVQDSPTVIHQVDETFRQLSEVYGKLSEGEFQLIRQTLLNFFQDLHIRVSTFLKDKVQNSNGRFVLPVSGPVPWGTEVPGVIRVFSVKGKEVKKMKFRHGGDYVAAQKEGSFELYGDRVLKLGTNMYSASRPVETHMSATSKNAASRAQENIVPNPLAKEELNFLARLMGGMEIKKPSGPEPGFRLNLFTTDEEEEHAALSRPEELSYEVISIQATQDQQRNEELARIMGEFEIT-EQLEQNTSKGDDLLAMMDRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2L033-1", "uniprot_id": "A0A0G2L033_DANRE", "id": "A0A0G2L033-1", "name": "", "aln": "MSTRTLPLLFINLGGEMLYILDQRLRAQNIPADKAKK----------VMNDIITTMFNKKFLEELFKPQELYSKKALRTVFDRLAHASIMRLNQASMDKLYDLMTMAFKYQVLLCPRPKDILLVSFNHMDAIRDFVKDTPSILSQVDETNKQLIEIYTSLSGGEFQLIRQTLLIFFQDMHIRVSIFLKDKVQNSNGRFVLPTSGPVPFGTQTPGLIRIFSCSGEEVRRTQFRDGGNYHTALREGSFEMYGDRVIKLGTNMYSVSRPVETHMSGTSKNSSQHTKVNTTPNPLAKEELNLLARLMGGLEVQKPPSTDSGFRVNLFATDEEEEEAFISRPDELSYEVINIQATKDKQTNAELAKIMGEFGETGEASPSSSSKGDDLLAMMDGL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.*******:********:***********.***:* *:****:****:**::*****************::********:*****************************:***:***:*:*:.*::*:*::: ***** :** *:* ** *********** ****:***** ********.*******.*****:**:.**:**:*. .*:**:: :*:.**:* .* :*****:*****:********..:*****:*.:*** :. :: . .**********:*******:*::**...:.***:***:******.* ::**:*******.****:*:* . ***:***** * * .:*********** *", "identical_positions": 271, "similar_positions": 82, "identity": "69.49%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110822-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AKP6-1", "uniprot_id": "A0A8I6AKP6_RAT", "id": "A0A8I6AKP6-1", "name": "E3 ubiquitin-protein ligase RNF213", "aln": "--MGCPQCGHVSSEKAAKFCSQCGQKLSPAATEQ-DLKNNNALVEASTT--EGKTEPGEVLREEVVLLSSTDSGKELQTEQGEVLREEVVLLSSTDSGKELQNPEESESDASWTTHVSKKEKRRRRRQGTISSS----EAASMSSGLWSLDLPSGPGSHNSALPQNQAQQGGTANQPGHSLDTVKMPVEKDGSACVEGSG-SSLRGPVAEGP-----EDAQRNPAASDYVEVKDLKTSNPSVDKG----------------PKMTDASQKASLPESKGEQP---------------GHGEKVPPIDTAANPVKRARKETRDDVQKQKPSPVSLATSKDRDQKAELESKLATPVRKSDESRNTQ--PEDQKKPGGDRNYAAAAKNKNQ---QAAALEATKS-THDPGDRVTVCFHAIVSRDFGFNPDKHRAYVRGGEGLGQKGWT-DACEMYYTQDLHDLGSLIEGKMDIPRQSLDKPIPYKYVIHHGSSSKDSVEYEFIYEQPQKKGEHVNRCLQVDSTLLSSGDWHQYDDIIWMRSPGLLQQAKNYITDGTRKNLVRGKKQAAVIMLDRIFSVLQSWSAINLQTFMTQFRQFYSVVRVPMIHDGHARKWSSLQYEEREVRLNLWEHVKKLMMPFLEGKSGESLPADCPVRSKQILGLSILCMVEAADFTVPKKDLDSLCYLLIPSADSPEALHRDLSPVLSIRQRWHAYLITLCFRCIEVGCDRWLGILPLLHYCMQQSPPRKNSKSQTEDVWAGLEGISFSEFRDKAS----ARSQALQLMQNRMALLHVDEYLFRSWFSLVPLESLSSYLENSEEYLSHMPTRVLDCFQGISYRLRGLGKISKQNIE----DVKKVFKILMYLVDMYQDRIFEESLPQIYLTECADLHETVCSITADRQFYQTPALSAELVCAVLQLSPPEHTEEGLVAKSYEDLVRTTFQEALNTTRKWLRTVFKSPMLSRNFAAVQLSYPDEMAVWRRLVGIN---FPEKYGWKGPLLGDMEGRLKQE--SPRLQISFFCSSHCCDEGPHDSVARSIEKCVIEAVSSVCQSQTSVLEGLSCQDLQKFGTLLSAVITKSWPVHNGELVSDVDEIFKYLLKWPDVRQLFKLCGTNENITNHITKE-GRRLMVTAESVFQKVAGELENGTIVVGQLELILKYKSQFLGIWDINSQRLQFQEKVYDMKGLLDRRKDDLFFLKREKRYVESLLTQLGRVKHFVQVELG----NIERIHSQDLSNKKLNEAVIK----PPNSSFSNRKTHYYLSPDILEMASKLDSLKDSHVFQDFWHETAELLSNDTLDQDRRELK-----------LSLPDVVDHLYYPCYEKFYKLYMNLRSGEITFADVDVIFR--DFKDKYDELNVDLKFMCTLDPQDRKGWISQRVRQIKEYHTLYQAVSSAKVIVQVRRALGVTGDFSVLNPLLNFADDFEDFRNEKLNQISPQFIKAKELLQDISELRHRCLEELALQTELVHWLHEALKDINELKVFVDLASISAGENDIDVDRVACFHDAVQGYASLLYKLGANTDFNEFMNHLQELWRALDNDQHLPDKLKDSARNLEWLKTVKESHGSVELSSLSLATAINSRGIYIIQAPKDGQKVSPDTVLHLLLPDDHGYQEAFRKYSTEELKELLNKLMLMSGRKDHSSNVEVETFSEVFSNMQRLVHVFINLHCAGNMLFRTWTAKVYCCP--GGGISMDFGSKLLNQLTESGDVIQLLGALCRQMEDFLHEWKTVVAQKRATHFYLNLYTAEQLVYLSSELR-----KPRPSEAALMMLSFIKGKCTVQELIQATSACEN-------KAARHCLQEAMRKLPQQLLSESTLMGKLRVIMTQSLECMSAFLPSCLDLDTLGRCLAHLARLGGSPVERPLPKGLQVGQPNLILCGHSEVLSAALAIYMQDPMQPLPTFDEVLLCTPGTTIEEVELFLRRCLT-LDSQEHKVYSLLFADQLSYEVGCQAEELFQSLSTQVHREDYQLVILCDAAREHCYIPSTFSQHKVPLVPQAPLPDIQAYLENHYQVPKQIQSAATVFRDGLCVGIVTSERAGVGKSLYVNTLHKKLKTKLQDETVPLKIIRLTEPHIDENHVLSALLPFLEKNYQKTPVIFHIDVSTSVQTGIPVFLFKLLILQYLMDINGKMWRRNPCHLYVVEIPQAHSVRPKRSS-KLNARAPLFKFLDIFPKVTCRPPKEVINMELTPKRS-HIEPGMDPAEFCSEAFQRPYQYLRRFHQGQNLDAFRYEKDSVEGSPEECLQHFLIYCGLTNPSWSELRNFAWFLNCQLKDCEASVFCNSAFTGDTLRGFKNFVVTFMVLMARDFATPTLQTSDQSPGKHSATIDGVAEEDLAPFSLRKRWESEPHPYVFFNGDRMTMTFIGFHLKTNSNGYVDAINPSSGNIIKKDVMTKELFDGLKLQRVPFNINFDSLPRHEKLERLCLALGIEWPS-----DPDETYELTTDNMLKILAIEMRFRCGIPVIIMGETGCGKTRLIKFLSDLRRGSIEAETMKLVKVHGGTTPSMIYSRVKDAERTAFFNKAQHNLETILFFDEANTTDAVSCIKEVLCDRTVGGEHLNEDSGLHVIAACNPYRKHSQEMIHRLESAGLGYRVGAEETADRLGSIPLRQLVYRVHALPPSLIPLVWDFGQLNDSAERLYIQQIVQRLVDSVTVDQRETFVIANVLSASQEFMRKRENECGFVSLRDVERCVKVFQWFHDHSNMLLNKLADFLRECCDSTPAFERDPVLWSLVMAIGVCYHASLEEKAPYRAAIARCLPKPYNSPKVILNEITHVQDLFLRDAPIRSNIARNLALKENVFMMVICIELKIPLFLVGKPGSSKSLAKIIVADAMQGQAASSDLFRCLKQVHLVSFQCSPHSTPQGIISTFKQCARFQQGKDLQQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGCIE-DDPAPYKQVGFVGISNWALDPAKMNRGIFVSRGSPNEKELIESAEGICSSDRLVQDRIRGYFAPFAKAYETVCQKQDKEFFGLRDYYSLIKMVFAKAKASKKGLSPRDIAHAVLRNFSG-KDDIQALSIFTASLPETLYKEEVSTVELIKQNIHPDLQGSSRG-LDSADSRYLLVLTRNYVALQILQQTFFEG-----QQPEIIFGSSFPQDQEYTQICRNINRVKVCMETGKMVVLLNLQNLYESLYDALNQYYVYLGGQKYVDLGLGTHRVKCRVHTDFRLIVIEEKDVVYKQFPVPLINRLEKHYLDMNTVLQGWQKGIVQELQRWAHEFADVKADQFIARHKYSPADVFIGYHSHACASVVLQAVERQGCRNLTEELYR---------------------------------------------------------------------------------KVFEEAKFILLDCATPDAVVRLSGSSLGSFAANRLSQEYYYKQQHNSFVDFLLAHLRMDHHECWAVFTEITTFSRLLTSHDCDVLESELRGLAPKPIVLSLQQFDTEYSFLKDVRSCLRNPA-RRKILVIQTDFDDGIHSAQLVASAKYSAINEINKTQGTEDFVFVYFVTKLSRMGS------GTPYVGFHGGLWRSVHIDDLRRSTVMASDVTKLQNVTISQLFEPVDKPEP------EDDPEEEMETESSKS---GEVAEEQMEVEEEGSEEMKRACDLRGCDV---LDTTRLVRSCVQGAVGMLRDQSESCARNMRRVTILLDLLNEESTLNASFLRESKMRLHVLLNKQEENQVRSLKEWVTREAANQDALQEAGTFRHTLWKRVQDVVTPILASMISHIDRDGNLELLARPGSPAWAQDLWMFIYSDIKFLNIPLALNNTRSNSEMPFILVQSHMNLLKDACNAVPFSWRIRDYLEELWVQAQYITDTEG----LSKKFVEIFQKTPLGLYLAQFPTAQQQELLQSYLKDFLLLTMKVSSREELMFLQMALRSCLSELQVASGT--PEE----GLSLPWVHLAYQHFRTRLQNFSRILTIHPQVLSSLSQAAEKHNLAGCEMTLDAFAAMACAEILKGDILKPSPRVWLQLVKNLSMPLELVCSEGYLQDSGSMTRAIIQEVRALWNRIFSIALFVEHVLLGTESQIPELSPLVTKYVSLLDKCLEEDSNLKTYRPFAAVMTTLCNCKDKASKKFCRFGIQPCSICQGDAQDPVCLPCDHVYCLPCIQTWLAP-GQMICPYCKTELPDKFSPTVS--QNHRKAIEKHAQFRHMCNSFFVDLVSTMCFKDNIPPQKSVIDTLLSLLFVQKELLRDASQRHREHTKSLSPFDDVVDKTPVIRSVVLKLLLKYSFHEVKGYIQNYLSQLENKAFLTEDKTELYLLFINCLEDSVYQKTSAGCRNHER-VLREEGHFLRTYSPGLRGSEPVRTASVEYLQEMARVRLCLDLAADFLSELQEG-SELAEDKRCFLKHVEQFCTRVNNDWHRVYLVRKLSSQRGMEFVQSFSRQGHPYQWVFPREVLAQQ---KDHLSQLDRYLVHGDEYKAVRDAMAKAVLDCKTLDVGNALSTCRSPKDQQTAYLLLALYTEVTALYRSRNGSLHPDSKQLEAMNKFINESKILSAPKINRFAKS-LVANTLPLLQTRSANGSLRVTVTEMAIHVATILLCGQDKVLEPLRNLAFYPFKMVNAFLPTMPEDLLVHAKFWEGLTNVRWYTCPNGHPCSVGECGQPMEMSICPDCRVPIGGLNHKPSVGFDVIRNNEDRTQTGHVLGNPQSSGTAEASDRGQSPVVFILTRLLTHLAMLVGAAQTPQALMNIIKPPVQDPQGFLEQHIQRDLEQLTKILGKSADETTHVVHLILSSLLKEQHQM----TLNFTEVLSTKGCRNNWEKHFGTLLLR-ELKHLDKTLPAINARISQDERISSNPVTKIIYGDPATFLPHLPQKSVVHCSKIWSCRTKITVEYLQHIVEQKNGKETVPLLWHFLQKEAELRLVKFLPEILALQRDLVKQFQNVSEVEFSSIRSFIHSHHSDGLQKLLHDRITVFLSTWNALRRSLETNGEIKLPKDYCRSDLDLDAKFEVILPRRRGLGLCGTALVSYLISLHNKMVYVVQKLSNE-DNSYSVDTSEVADLHVISYDVERDLNPLILSNCQYQVQQGGETSQEFDLEKIQRQISSRFLQGKPRLTLKGIPTLVYRRDWNYEHLFMDIKNKMTQNPLPNSAINAISGQLQSYSDACEALSIVEVTLGFLSTAGGDPSMELNVYIQEVLQMCDQTSQVLKALNRCQLRHIIALWQFLSAHKSERRLRLKKELFQEVDVKYKEDLSPRHARLLSTFLNEAGLDSFLLELHEMIVLKLRGA--QAESSFNPSWSLKDTLVSYMETKDSDVLTEVESQFPDEILMSSCVSVWKTAATRKWDRQSR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q555-1", "uniprot_id": "RN213_MOUSE", "id": "E9Q555-1", "name": "E3 ubiquitin-protein ligase RNF213", "aln": "--MECPQCGHVSSEKAPKFCSECGQKLPSAATVQGDLKNDNTLVVSSTP--EGKT------------------------EQGAVLREEEVLLSSTDPGKELEKPEESDSNASWTTQMSKKEKRRRKRQGTISSS----EAP--SSGLWSLDMPPSPGSHNSALPQNQAQQGGAASQPGHPLDTENMPME-DGFVHTEGSG-SPLQGQAAER------TDAQSNLAPSDLAEVKDLNTSKPSVDKGLPLDGG-PALSAFKGHPKMTDASQKAPLPESKGETS---------------GQEKKVPPIDAAASPVKTAGKETGEDVRKPKPSPVSPVASKHGDQEAELKGKLATPVRKSNEGGNTQ--PEDQRKPGEGRNFAAAVKTQQAAAPQQAAAPEPTS-AFNPRDTVTVYFHAIVSRHFGFNPEEHKVYVRGGEGLGQKGWT-DACEMYCTQDLHDLGSLVEGKMDIPRQSLDKPIPYKYVIHRGGSSKDTVEYEFIYEQAQKKGEHVNRCLRVVSTSLGNGDWHQYDDIICMRSTGFFQQAKNRILDSTRKELLKGKKQAAVVMLDRIFSVLQPWSDINLQSFMTQFLQFYSVVREPMIHDGRARKWTSLQYEEKEVWTNLWEHVKKQMAPFLEGKSGESLPADCPVRSKLTLGLSILFMVEAAEFTVPKKDLDSLCYLLIPSAGSPEALHSDLSPVLRIRQRWRIYLTNLCLRCIDERCDRWLGILPLLHTCMQKSPPKKNSKSQPEDTWAGLEGISFSEFRDKAP----TRSQPLQFMQSKMALLRVDEYLFRSWLSVVPLESLSSYLENSIDYLSDVPVRVLDCLQGISYRLPGLRKISNQNMKK---DVENVFKMLMHLVDIYQHRIFGENLLQIYLTECLTLHETVCNITANHQFFEIPALSAELICKLLELSPPGHTDEGLPEKSYEDLVTSTLQEALATTRNWLRSLFKSRMLSISSAYVRLTYSEEMAVWRRLVEIG---FPEKHGWKGSLLGDMEGRLKQE--PPRLQISFFCSSQCRDGGLHDSVSRSFEKCVIEAVSSACQSQTSVLEGLSCQDLQKFGTLLSAVITKSWPVHNGEPVFDVDEIFKYLLKWPDVRQLFELCGTNEKIIDNITEE-GRQLMATAESVFQKVAGELENGTIVVGQLELILEHQSQFLDIWNLNRRRLPSQEKACDVRSLLKRRRDDLLFLKQEKRYVESLLRQLGRVKHLVQVDFG----NIEIIHSQDLSNKKLNEAVIK----LPNSSSYKRETHYCLSPDIREMASKLDSLKDSHIFQDFWQETAESLN--TLDKDPRELK-----------VSLPEVLEYLYNPCYDNFYTLYENLKSGKITFAEVDAIFK--DFVDKYDELKNDLKFMCTMNPQDQKGWISERVGQIKEYHTLHQAVSSAKVILQVRRALGVTGDFSVLNPLLNFADSFEDFGNEKLDQISPQFIKAKQLLQDISEPRQRCLEELARQTELVAWLHKALEDINELKVFVDLASISAGENDIDVDRVACFHDAVQGYASLLYKMDERTNFSDFMNHLQELWRALDNDQHLPDKLKDSARNLEWLKTVKESHGSVELSSLSLATAINSRGVYVIEAPKDGQKISPDTVLRLLLPDGHGYPEALRTYSTEELKELLNKLMLMSGKKDHNSNTEVEKFSEVFSNMQRLVHVFIKLHCAGNMLFRTWTAKVYCCP--DGGIFMNFGLELLSQLTEKGDVIQLLGALCRQMEDFLDNWKTVVAQKRAEHFYLNFYTAEQLVYLSSELR-----KPRPSEAALMMLSFIKGKCTVQDLVQATSACES-------KADRYCLREVMKKLPQQLLSEPSLMGKLQVIMMQSLVYMSAFLPHCLDLDALGRCLAHLATMGGTPVERPLPKGLQAGQPNLILCGHSEVLPAALAIYMQAPRQPLPTFDEVLLCTPATTIEEVELLLRRCLT-SGSQGHKVYSLLFADQLSYEVGCQAEEFFQSLCTRAHREDYQLVILCDAAREHCYIPSTFSQYKVPLVPQAPLPNIQAYLQSHYQVPKRLLSAATVFRDGLCVGIVTSERAGVGKSLYVNTLHTKLKAKLRDETVPLKIIRLTEPHLDENQVLSALLPFLKEKYQKMPVIFHIDISTSVQTGIPIFLFKLLILQYLMDINGKIWRRSPGHLYLVEIPQGLSVQPKRSS-KLNARAPLFKFLDLFPKVTCRPPKEVIDMELTPERS-HTDPAMDPVEFCSEAFQRPYQYLKRFHQQQNLDTFQYEKGSVEGSPEECLQHFLIYCGLINPSWSELRNFAWFLNCQLKDCEASIFCKSAFTGDTLRGFKNFVVTFMILMARDFATPTLHTSDQSPGRQSVTIGEVVEEDLAPFSLRKRWESEPHPYVFFNGDHMTMTFIGFHLETNNNGYVDAINPSNGKVIKKDVMTKELFDGLRLQRVPFNIDFDNLPRYEKLERLCLALGIEWPI-----DPDETYELTTDNMLKILAIEMRFRCGIPVIIMGETGCGKTRLIKFLSDLKRGSVEAETMKLVKVHGGTTPSMIYSKVKEAERTAFSNKAQHKLDTILFFDEANTTEAVSCIKEILCDRTVDGEHLHEDSGLHIIAACNPYRKHSQEMILRLESAGLGYRVSAEETADRLGSIPLRQLVYRVHALPPSLIPLVWDFGQLNDSAEKLYIQQIVQRLVDSVSVNPSETCVIADVLSASQMFMRKRENECGFVSLRDVERCVKVFRWFHDHSDMLLKELDKFLHESSDSTHTFERDPVLWSLVMAIGVCYHASLEEKASYRTAIARCFPKPYNSSRAILDEVTHVQDLFLRGAPIRTNIARNLALKENVFMMVICIELKIPLFLVGKPGSSKSLAKIIVADAMQGQAAFSELFRCLKQVHLVSFQCSPHSTPQGIISTFKQCARFQQGKDLGQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGCIE-DDPAPYKKVGFVGISNWALDPAKMNRGIFVSRGSPNEKELIESAEGICSSDRLVQDKIRGYFAPFAKAYETVCQKQDKEFFGLRDYYSLIKMVFAKAKASKRGLSPQDITHAVLRNFSG-KDNIQALSIFTASLPEARYKEEVSTVELIKQNIYPGPQASSRG-LDGAESRYLLVLTRNYVALQILQQTFFEG-----QQPEIIFGSSFPQDQEYTQICRNINRVKICMETGKMVVLLNLQNLYESLYDALNQYYVYLGGQKYVDLGLGTHRVKCRVHTAFRLIVIEEKDVVYKQFPVPLINRLEKHYLDMNTVLQPWQKSIVQELQQWAHEFADVKADQFIARHKYSPADVFIGYHSDACASVVLQAVERQGCRDLTEELYR---------------------------------------------------------------------------------KVSEEARSILLDCATPDAVVRLSGSSLGSFTAKQLSQEYYYAQQHNSFVDFLQAHLRMTHHECRAVFTEITTFSRLLTGNDCDVLASELRGLASKPVVLSLQQYDTEYSFLKDVRSWLTNPG-KRKVLVIQADFDDGTRSAQLVASAKYTAINEINKTQGTKDFVFVYFVTKLSRMGS------GTSYVGFHGGLWRSVHIDDLRRSTIMASDVTKLQNVTISQLFKPEDKPE-----------QEEMEIETSQS---KELAEEQMEVED--SEEMKKASDPRSCDCSQFLDTTRLVQSCVQGAVGMLRDQNESCARNMRRVTILLDLLNEDNTRNASFLRESKMRLHVLLNKQEENQVRSLKEWVTREAANQDALQEAGTFRHTLWKRVQDVVTPILASMIAHIDRDGNLELLAQPDSPAWVQDLWMFIYSDIKFLNISLVLNNTRSNSEMSFILVQSHMNLLKDAYNAVPFSWRIRDYLEELWVQAQYITDTEG----LSKKFVEIFQKTPLGVFLAQFPVAQQQKLLQSYLKDFLLLTMKVSSREELMFLQMALWSCLRELQEASGT--PDETYKFPLSLPWVHLAFQHFRTRLQNFSRILTIHPQVLSSLSQAAEKHSLAGCEMTLDAFAAMACAEMLKGDLLKPSPKAWLQLVKNLSTPLELVCSEGYLCDSGSMTRSVIQEVRALWNRIFSIALFVEHVLLGTESHIPELSPLVTTYVSLLDKCLEEDSNLKTCRPFVAVMTTLCDCKDKASKKFSRFGIQPCFICHGDAQDPVCLPCDHVYCLRCIQTWLIP-GQMMCPYCLTDLPDKFSPTVS--QDHRKAIEKHAQFRHMCNSFFVDLVSTMCFKDNTPPEKSVIDTLLSLLFVQKELLRDASQKHREHTKSLSPFDDVVDQTPVIRSVLLKLLLKYSFHEVKDYIQNYLTQLEKKAFLTEDKTELYLLFISCLEDSVHQKTSAGCRNLEQ-VLREEGHFLRTYSPGLQGQEPVRIASVEYLQEVARVRLCLDLAADFLSELQEG-SELAEDKRRFLKHVEEFCTRVNNDWHRVYLVRKLSSQRGMEFVQSFSKQGHPCQWVFPRKVIAQQ---KDHVSLMDRYLVHGNEYKAVRDATAKAVLECKTLDIGNALMACRSPKPQQTAYLLLALYTEVAALYRSPNGSLHPEAKQLEAVNKFIKESKILSDPNIRCFARS-LVDNTLPLLKIRSANSILKGTVTEMAVHVATILLCGHNQILKPLRNLAFYPVNMANAFLPTMPEDLLVHARTWRGLENVTWYTCPRGHPCSVGECGRPMQESTCLDCGLPVGGLNHTPHEGFSAIRNNEDRTQTGHVLGSPQSSGVAEVSDRGQSPVVFILTRLLTHLAMLVGATHNPQALTVIIKPWVQDPQGFLQQHIQRDLEQLTKMLGRSADETIHVVHLILSSLLRVQSHG----VLNFNAELSTKGCRNNWEKHFETLLLR-ELKHLDKNLPAINALISQDERISSNPVTKIIYGDPATFLPHLPQKSIIHCSKIWSCRRKITVEYLQHIVEQKNGKETVPVLWHFLQKEAELRLVKFLPEILALQRDLVKQFQNVSRVEYSSIRGFIHSHSSDGLRKLLHDRITIFLSTWNALRRSLETNGEIKLPKDYCCSDLDLDAEFEVILPRRQGLGLCGTALVSYLISLHNNMVYTVQKFSNE-DNSYSVDISEVADLHVISYEVERDLNPLILSNCQYQVQQGGETSQEFDLEKIQRQISSRFLQGKPRLTLKGIPTLVYRRDWNYEHLFMDIKNKMAQSSLPNLAISTISGQLQSYSDACEALSIIEITLGFLSTAGGDPGMDLNVYIEEVLRMCDQTAQVLKAFSRCQLRHIIALWQFLSAHKSEQRLRLNKELFREIDVQYKEELSTQHQRLLGTFLNEAGLDAFLLELHEMIVLKLKGP--RAANSFNPNWSLKDTLVSYMETKDSDILSEVESQFPEEILMSSCISVWKIAATRKWDRQSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q63HN8-3", "uniprot_id": "RN213_HUMAN", "id": "Q63HN8-3", "name": "E3 ubiquitin-protein ligase RNF213", "aln": "--MECPSCQHVSKEETPKFCSQCGERLPPAAPIADSENNNSTMASASEG--EMEC--------------------------GQELKEEGGPCLFPGSDSWQENPEEPCSKASWTVQESKKKKRKKKKKGNKSASSELASLPLSPASPCHLTLLSNPWPQDTALPHSQAQQSGPTGQPSQPPGTATTPLEGDGLSAPTEVGDSPLQAQALGEAGVATGSEAQSSPQFQDHTEGEDQDASIPSGGRGLSQEGTGPPTSAGEGHSRTEDAAQELLLPESKGGSSEPGTELQTTEQQAGASASMAVDAVAEPANAVKGAGKEMKEKTQRMKQPPATTPPFKTHCQEAETKTKDEMAAAEEKVGKNEQGEPEDLKKPEGKNRSAAAVKNEKEQKNQEADVQEVKASTLSPGGGVTVFFHAIISLHFPFNPDLHKVFIRGGEEFGESKWDSNICELHYTRDLGHDRVLVEGIVCISKKHLDKYIPYKYVIYNG----ESFEYEFIYKHQQKKGEYVNRCLFIKSSLLGSGDWHQYYDIVYMKPHGRLQKVMNHITDGPRKDLVKGKQIAAALMLDSTFSILQTWDTINLNSFFTQFEQFCFVLQQPMIYEGQAQLWTDLQYREKEVKRYLWQHLKKHVVPLPDGKSTDFLPVDCPVRSKLKTGLIVLFVVEKIELLLEG-SLDWLCHLLTSDASSPDEFHRDLSHILGIPQSWRLYLVNLCQRCMDTRTYTWLGALPVLHCCMELAPRHKDAWRQPEDTWAALEGLSFSPFREQML----DTSSLLQFMREKQHLLSIDEPLFRSWFSLLPLSHLVMYMENFIEHLGRFPAHILDCLSGIYYRLPGLEQVLNTQDVQDVQNVQNILEMLLRLLDTYRDKIPEEALSPSYLTVCLKLHEAICSSTKLLKFYELPALSAEIVCRMIRLLS-LVDSAGQRDETGNNSVQTVFQGTLAATKRWLREVFTKNMLTS--SGASFTYVKEIEVWRRLVEIQ---FPAEHGWKESLLGDMEWRLTKE--EPLSQITAYCNSCWDTKGLEDSVAKTFEKCIIEAVSSACQSQTSILQGFSYSDLRKFGIVLSAVITKSWPRTADN----FNDILKHLLTLADVKHVFRLCGTDEKILANVTED-AKRLIAVADSVLTKVVGDLLSGTILVGQLELIIKHKNQFLDIWQLREKSLSPQDEQCAVEEALDWRREELLLLKKEKRCVDSLLKMCGNVKHLIQVDFG----VLAVRHSQDLSSKRLNDTVTVR---LSTSSNSQRATHYHLSSQVQEMAGKIDLLRDSHIFQLFWREAAEPLSEPKEDQEAAELLSEPEEESERHILELEEVYDYLYQPSYRKFIKLHQDLKSGEVTLAEIDVIFK--DFVNKYTDLDSELKIMCTVDHQDQRDWIKDRVEQIKEYHHLHQAVHAAKVILQVKESLGLNGDFSVLNTLLNFTDNFDDFRRETLDQINQELIQAKKLLQDISEARCKGLQALSLRKEFICWVREALGGINELKVFVDLASISAGENDIDVDRVACFHDAVQGYASLLFKLDPSVDFSAFMKHLKKLWKALDKDQYLPRKLCDSARNLEWLKTVNESHGSVERSSLTLATAINQRGIYVIQAPKGGQKISPDTVLHLILPESPGSHEESREYSLEEVKELLNKLMLMSGKKDRN-NTEVERFSEVFCSVQRLSQAFIDLHSAGNMLFRTWIAMAYCSPKQGVSLQMDFGLDLVTELKEGGDVTELLAALCRQMEHFLDSWKRFVTQKRMEHFYLNFYTAEQLVYLSTELR-----KQPPSDAALTMLSFIKSNCTLRDVLRASVGCGS-------EAARYRMRRVMEELPLMLLSEFSLVDKLRIIMEQSMRCLPAFLPDCLDLETLGHCLAHLAGMGGSPVERCLPRGLQVGQPNLVVCGHSEVLPAALAVYMQTPSQPLPTYDEVLLCTPATTFEEVALLLRRCLT-LGSLGHKVYSLLFADQLSYEVARQAEELFHNLCTQQHREDYQLVMVCDGDWEHCYLPSAFSQHKVFVTPQAPLEAIQAYLAGHYRVPKQTLSAAAVFNDRLCVGIVASERAGVGKSLYVKRLHDKMKMQLNVKNVPLKTIRLIDPQVDESRVLGALLPFLDAQYQKVPVLFHLDVTSSVQTGIWVFLFKLLILQYLMDINGKMWLRNPCHLYIVEILERRTSVPSRSSSALRTRVPQFSFLDIFPKVTCRPPKEVIDMELSALRS-DTEPGMDLWEFCSETFQRPYQYLRRFNQNQDLDTFQYQEGSVEGTPEECLQHFLFHCGVINPSWSELRNFARFLNYQLRDCEASLFCNPSFIGDTLRGFKKFVVTFMIFMARDFATPSLHTSDQSPGKHMVTMDGVREEDLAPFSLRKRWESEPHPYVFFNDDHTTMTFIGFHLQPNINGSVDAISHLTGKVIKRDVMTRDLYQGLLLQRVPFNVDFDKLPRHKKLERLCLTLGIPQAT-----DPDKTYELTTDNMLKILAIEMRFRCGIPVIIMGETGCGKTRLIKFLSDLRRGGTNADTIKLVKVHGGTTADMIYSRVREAENVAFANKDQHQLDTILFFDEANTTEAISCIKEVLCDHMVDGQPLAEDSGLHIIAACNPYRKHSEEMICRLESAGLGYRVSMEETADRLGSIPLRQLVYRVHALPPSLIPLVWDFGQLSDVAEKLYIQQIVQRLVESISLDENGTRVITEVLCASQGFMRKTEDECSFVSLRDVERCVKVFRWFHEHSAMLLAQLNAFLSKSSVSKNHTERDPVLWSLMLAIGVCYHASLEKKDSYRKAIARFFPKPYDDSRLLLDEITRAQDLFLDGVPLRKTIAKNLALKENVFMMVVCIELKIPLFLVGKPGSSKSLAKTIVADAMQGPAAYSDLFRSLKQVHLVSFQCSPHSTPQGIISTFRQCARFQQGKDLQQYVSVVVLDEVGLAEDSPKMPLKTLHPLLEDGCIE-DDPAPHKKVGFVGISNWALDPAKMNRGIFVSRGSPNETELIESAKGICSSDILVQDRVQGYFASFAKAYETVCKRQDKEFFGLRDYYSLIKMVFAAAKASNRKPSPQDIAQAVLRNFSG-KDDIQALDIFLANLPEAKCSEEVSPMQLIKQNIFGPSQKVPGGEQEDAESRYLLVLTKNYVALQILQQTFFEGD----QQPEIIFGSGFPKDQEYTQLCRNINRVKICMETGKMVLLLNLQNLYESLYDALNQYYVHLGGQKYVDLGLGTHRVKCRVHPNFRLIVIEEKDVVYKHFPIPLINRLEKHYLDINTVLEKWQKSIVEELCAWVEKFINVKAHHFQKRHKYSPSDVFIGYHSDACASVVLQVIERQGPRALTEELHQ---------------------------------------------------------------------------------KVSEEAKSILLNCATPDAVVRLSAYSLGGFAAEWLSQEYFHRQRHNSFADFLQAHLHTADLERHAIFTEITTFSRLLTSHDCEILESEVTGRAPKPTLLWLQQFDTEYSFLKEVRNCLTNTA-KCKILIFQTDFEDGIRSAQLIASAKYSVINEINKIRENEDRIFVYFITKLSRVGR------GTAYVGFHGGLWQSVHIDDLRRSTLMVSDVTRLQHVTISQLFAPGDLPELGLEHRAEDGHEEAMETEASTSGEVAEVAEEAMETES--SEKVGKETSELGGSDVSILDTTRLLRSCVQSAVGMLRDQNESCTRNMRRVVLLLGLLNEDDACHASFLRVSKMRLSVFLKKQEESQFHPL-EWLAREACNQDALQEAGTFRHTLWKRVQGAVTPLLASMISFIDRDGNLELLTRPDTPPWARDLWMFIFSDTMLLNIPLVMNNERHKGEMAYIVVQNHMNLSENASNNVPFSWKIKDYLEELWVQAQYITDAEG----LPKKFVDIFQQTPLGRFLAQLHGEPQQELLQCYLKDFILLTMRVSTEEELKFLQMALWSCTRKLKAASEA--PEE----EVSLPWVHLAYQRFRSRLQNFSRILTIYPQVLHSLMEARWNHELAGCEMTLDAFAAMACTEMLTRNTLKPSPQAWLQLVKNLSMPLELICSDEHMQGSGSLAQAVIREVRAQWSRIFSTALFVEHVLLGTESRVPELQGLVTEHVFLLDKCLRENSDVKTHGPFEAVMRTLCECKETASKTLSRFGIQPCSICLGDAKDPVCLPCDHVHCLRCLRAWFAS-EQMICPYCLTALPDEFSPAVS--QAHREAIEKHARFRQMCNSFFVDLVSTICFKDNAPPEKEVIESLLSLLFVQKGRLRDAAQRHCEHTKSLSPFNDVVDKTPVIRSVILKLLLKYSFHDVKDYIQEYLTLLKKKAFITEDKTELYMLFINCLEDSILEKTSAYSRNDELNHLEEEGRFLKAYSPASRGREPANEASVEYLQEVARIRLCLDRAADFLSEPEGG-PEMAKEKQCYLQQVKQFCIRVENDWHRVYLVRKLSSQRGMEFVQGLSKPGRPHQWVFPKDVVKQQGLRQDHPGQMDRYLVYGDEYKALRDAVAKAVLECKPLGIKTALKACKTPQSQQSAYFLLTLFREVAILYRSHNASLHPTPEQCEAVSKFIGECKILSPPDISRFATS-LVDNSVPLLRAGPSDSNLDGTVTEMAIHAAAVLLCGQNELLEPLKNLAFSPATMAHAFLPTMPEDLLAQARRWKGLERVHWYTCPNGHPCSVGECGRPMEQSICIDCHAPIGGIDHKPRDGFHLVKDKADRTQTGHVLGNPQRR-DVVTCDRGLPPVVFLLIRLLTHLALLLGASQSSQALINIIKPPVRDPKGFLQQHILKDLEQLAKMLGHSADETIGVVHLVLRRLLQEQHQLSSRRLLNFDTELSTKEMRNNWEKEIAAVISP-ELEHLDKTLPTMNNLISQDKRISSNPVAKIIYGDPVTFLPHLPRKSVVHCSKIWSCRKRITVEYLQHIVEQKNGKERVPILWHFLQKEAELRLVKFLPEILALQRDLVKQFQNVQQVEYSSIRGFLSKHSSDGLRQLLHNRITVFLSTWNKLRRSLETNGEINLPKDYCSTDLDLDTEFEILLPRRRGLGLCATALVSYLIRLHNEIVYAVEKLSKE-NNSYSVDAAEVTELHVISYEVERDLTPLILSNCQYQVEEGRETVQEFDLEKIQRQIVSRFLQGKPRLSLKGIPTLVYRHDWNYEHLFMDIKNKMAQDSLPSSVISAISGQLQSYSDACEVLSVVEVTLGFLSTAGGDPNMQLNVYTQDILQMGDQTIHVLKALNRCQLKHTIALWQFLSAHKSEQLLRLHKEPFGEISSRYKADLSPENAKLLSTFLNQTGLDAFLLELHEMIILKLKNPQTQTEERFRPQWSLRDTLVSYMQTKESEILPEMASQFPEEILLASCVSVWKTAAVLKWNREMR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A8X0-1", "uniprot_id": "A0AB13A8X0_DANRE", "id": "A0AB13A8X0-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MTRKRKSGKKGKPLAQKKEAQKRGGSTSSSTTQKEGAQKGDGSSSSSTTQKDG-------------------AQKRDDSTSSSSTAQKEEGQKSDGSTSSSTTNKEGAQKRDGSTSSRLQKKGPQKRKGSTSSSR---AHSRSRSKSKQTSYPSQARSRSHGQHNISTTESGPLSKEAQTQTSASLLVDKDTQTETVGQASQQTQTEINGNT-----ETAEVSQPPQLSHEDVEMEGTVQPRTKG-----------------SESDGEKEESVKRKK----------------------RKLSEIGEPAKETEDSTKLSHECEEKVGDNQKNEDTNKHYGGDSLKDLKSVTEEPKSYAAAAATG---KTGKVSKEQTNQIEANQDSTMESKSTQRKPSPVRAPAGPPMLTFYIYAVLDKRFRFNEQYDSLFLDYGNGNIKLQMK--------HFNIGKDGYLIEATFSVEDSAVRG---------------GTIQYKYVVQQRQNQKSEIAVRYIEVPSYTTEKEFHLYEGYISCSSTVSITEWMMSLFHSEQKAVYKGWETSAHVLLDRIFLKWHPSNEESNMTFVQHLRSYKNAFESGFVEFPGNYTPFPIKVS-ELISAKLRMILKKESEALRTSES-----LDGVKSEALSVALSVFKVCCGCDVDLSLKDWGKLCQVVSECMGSFGEIQTTQTAPFINTVTG---LMNLCAKKLITEVVLLVPVLHLLRNSEVNEAGPGSS--MDEQRWTGLENISYQSFRERIRGLPDKRRMILKLIKDNLPMTKDNPKLLKSWLSLVAFEDVSEFVQLTGSFPELLIQSLMCRIIEAEKNTDANRTEKNLEVTG------KVLNLLLKSIKKDRERIMKTEQLKLILQCCCNVHKSVCKTARLVPQYKVTVLSFQLLLKMAEIVYDGFFKGGEQMKQHQNEVLSKLNIIQEDFRKWRVELLLKPLMQT----TGFTYPREMELWNDLYGIESSIPGVTERWKGFLDHDLRRRISQISDTDKIVVYVLVTSAKAVENSHANIQSCLKELCEAAIKNQCQSKKEGTLLCHLFSKTISWPVLSSIIVESAACFGED----------HKGRLLDPQSAINFFLSQDKWNEWKLEDGASQLIAESQSFLGRLIQTLCQGSIPLGHLKTIFKYKTQFQKLYNQYKNNNKEMNVSISVSDLLSQREDDLKAFEQQKGYMTNLINMLGKISDVINVPELSSLEEIAKTNVQEVALDKLVEVETYFSKDDLKKNNTRRVLFYSDDQQVQDMAREMHDVNSSNLILSFWQEKAKDYFMAGPELLS---------------LDLTEIYEDIWTPCLTKFLNFGNRIAVGQACFKEVEEALVGCGETGEGDRLKKEFMLMATMLDGHNENWPEQRLKQIREYRCLYDAAESAEVILKLKDRLGLQGDFSHIHSLTLVRD--DSFKQNTLGSLSEDLIKARQKLADVERRHTACLEAFLKSDTLIKWIKAEIPSLKELKVFMELATISAGENDADIDRLASFETAVMGYAPLLYSLPQNVGFEEFFDYAKQVLDTLNKDEKLGDKLVDSNRWLDWLKGLRETHGSVEQSSLSLASAINTGGVYHVGWP---DDFNGKTGLDNIFYVKVTKNNEEKTYRLNELLELQNKLMLMSSKGEKG-KEQVIKFTQVFEGIQRMGRILLQLHRSGNMLFRNWAAEITCNHQNQPCIQVKFPLLSKCIVYQG-EVEEELQKLSRSLEDFHKDWCNHLTKMRSQYYPLNHYSSEQIVYLCEWINSINIKKKPVPQQVWHLLTPIKPDCMLNDIKEAFEIATEPQSILQEDTAEELGPNSDFDLPLSFSLLDVSTECLEDLWKQFKENMSGFLTHHVDVETLGRFLSNLSNMNQLHIKRKIPSFLQEGRPNLVQCPAAELMSTTLSFYMESPENPLPTTDEVLMCQEETTEEEVEIFLRRCLGGAASNHKKIYTLVNPGSMSYDVSVALVEYFETQEVCAG-PYYRLVMVCPVN-QDRYIPSFFSNYKVQTGITISAERSQKYIRHHFKISYELATHSSVYPERLSVWMIASKRPAVGKSLYVRRLFEKFKGEFP--RATLLTIRLIDPYIDMDGFVQTLSERLAPLRQQDPVLLHIDVAAVCHG-LEEFLFKLLILECISDSKGTIWRRNKAHLVVIETLQRGHKTQTKME-------PSHGFLNTLPTIFCRPPKDIKEIMKTNESFRSLDPLMDKEEFESEDIQRPYQYLRRFNRSMNLDRFTYQAHSVEGDPVDCLHHLLSNYGLKDPSWAELKHFTWFLNLQLKDCEKSLFCDSDFCGETLSGFKDFIVKFMIHMARDFASPSIDISDQSP-----SFFSKNEDEEEILSFRKRWENESHPYIFFNADHVSMSFLGFHVKQN-GTILNAVDSKSGKVLMRNVMTQELFSDIQRQMINLSKDFDDLTREDKLQKMSFVVGAEKGCEKGKFDPDPTYELTTDNVMKMLAIHMRFRCEIPVIIMGETGCGKTRLVRFLCDLQREGRDVENMKLVKVHGGTTSETIYKKVREAEELAQKNRQKYKLDTVLFFDEANTTEAIFAIKEVLCDKTVKGYPLKKNSGLKIIAACNPYRRHTTKMVDRLERAGLGYRVKAEETEDRLGKVPMRQLVYRVHPLPPSMVPLVWDFGQLSDSTELSYIRQIVKKKMRDHRLPLSCQNVITNVLAASQKYMRNQADECSFVSLRDVERSMGVLLWFYNHRDIFFPSQDFPRFEN--------VQMVLKCLVLAVGVCYYPSLENKRPYLATISKCFPDQFNSEESLEQEIASCQDFLLKNIQTRETIAKNMALKENVFLMVVCIELRIPLFLVGKPGSSKSLAKTVIADAMQRQASHCDLFKKLKEVHMVSFQCSPHSSPEGIIGTFRNCARFQKDKNLDEYVSVVVLDEIGLAEDSPQMPLKTLHPLLEDGCIDSDNPESYMKVGFVGISNWALDPAKMNRGIFVSRWDPSEKDLVETAEGICSSSQPVLLKIKHLLSKLAKCFLSICKTDSEQFFGLRDYYGLIKMLFDTVKCSDQEPSDKELAEAVLRNFSGQRDGFDPLDYFKDIFQNIQNVQRPNTLNMIEQNLDHHIDK---------ECRYLLLLTTNNAALYIIQHHIFSKENYTQKCPEIVFGSGFPKDQEYAQICRNVSRIKACMETGRTVILLNLLNLYESLYDALNQYYVYFSGQQYVDLGLGSHRVKCRVHRDFRLVVVEDQEKVYKKFPVPLKNRLEKHKVDRSTDLAPWQHRVLEKLKKWAREFSKIQHSDSSE-ANFSVTDAFVGFHGDACASALLQALKKIDKLHHNKEENREESEAHHIDREFTEFQEKVNKFPDEAQEDDASMEVDKVQDAEIDEEMETLEDDSDLVKMVEGPVFVETRDKIESNKTMDEEEVYEIAKSFLLNCSTPDSVLRLKYSEFGNQETEELQKMYFHLQTHQSLRDLLNNHLNKTNQD-KNRFLEVTTFSNLLTGADVRNLGPALGLSTERFLLLSLHQFDTEASFCNKIQSFLRESGPSVHILLIQMDMEESLCKNELIASAKYCTMNEILHLKSDECNIYTVFITKLSRIGEQCTSITGDKYIGFQGGVWLSAHIDDLRDSDDLCLNLKAFCGIPISQLIS------------------------------------QTIESDVKESDEMNTNRQQSEKGDSVHLHSLSLLRSCTQKAVSLLRDTDEKTSRSMERMNILLGLLACDPGRTGARFQQVLLKRLVFALIQKEELIPNAKDWVYKVAKNHEALQECGTLRHTLWRYLQDFLTPVLARILEVIDRDCNLYQLYGEGLSEGLTQFWLDIFEDQQLLDLIPSQNTRAPDQEINVQCHLFVG--EVEQPCAAPYSWLIKTYCQSLWEESEFVRSSEQDIKARIQQFVSAVSGSRLGSYIQKLSDVENVELGQRYLTDYVLLAFKVNSEDEHWVLQSAVLGCVFTLQTMMSVSPE-------LSPSWIHAAAQIYNPRMDTLSHVLQLNPQLVSLIQQERPKRESPDMCEDILAVGICVEETKLLPVTSLTECLTFLQRVEQLQPCIERVLSPDYSALCSPGCLKYLETIQSVWQGILLVAVFIEKVVIKMKKGDERIIALTLKHCSQLHGLVEGSPDFRSKDNLQQIIRILNDYHEESISSELRYGVK-CRVCLMELSEPFALPCEHVFCRSCLRRSMEREEAQHCPVCREPLSNNYQPTVSTTLNYSFALKQHKEIIKCCNTFFLEVVSRFCLTDDQDPPDDLVELLFSLLIS--------AQGDVYKTRELTPFLECVDQSPVVRSVLPKLLMQYSLKQVKKHIQSYLEDLENKLLDKEDRTELYRLFVNCFQDTLLCSDSNGDHKHLRENTNFLSRLARKQTPSRQND------PAEFLMSMARLRMCLDSAAYILSKAICQKNNFVEAEFKFMEQVKAVCDYCDNDWYRVYLLRALNRQAGMDFLQALIN-STDYEWIFPAEMMRLH---RLIPAEVDRFLCCGQSYRALRDGVGESTQVGTTDGLKEALQASVGSSPLKNALLTLAVFRQVTCHFMSPERTLHPQEQQISILEKVIRDNMSGHAREFCTALLSNHIGGPGSNLRLGTGVPAQRRPVLELLVHACTVFYSG-NRLISPLFNIASQPQNMTGAFLPTMPDDHTSEAKQWLSEKKLKMYFCSNSHACFVGECGRPMAKSKCATCGVEIGGEGHIPVPGFTEAYGDYDRTRPGHILG--QARTRSEAPNRKLTLAQSCVLRLCLHLAMLQGLIHYQQGIRNMIHPEVSDVYQFLWQHLEKDMEVLGKTLTLNIDDSAIVIHLIFSRFLQTTPVAN--------VDLSTRKSREQWEITVCKTAISPVLQNLDRELNNAQDLIAADNRLSNSPLVKVLRGDPQRML-QLPANCPTEHSAFWSPSSVLAVESISQQIDQ----AQAPLLTLFVQKVHYIRQLDCLPALAALLSDLIKVLPPGSETQNHTIASLLHCIPAGHQKKLMSERVEIYMKVWNQLRMEISSNASLGLDSTHCEKDITSESSGQFLFPSRKGAGSCLHAVIDVLSETHNSLVREARKLCQQTDSDYKVPLAVLSKSQLALCHPEREFLPLVLANCHYTLEKGQQTVSSYDHQGIERELSRRFFAGKPRIQTD-TEKYLRRHHQNFTEVLNEVRAKIPQKVSGSSCSTNQHQVHHGASFGGEGHHFFSRSR--QSSGGTYLG--------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . * ..: * ..::. . ::.. :* : . :: .. . . :* .. . :. ::* ::::*. *:* . : . . .:. . : .: :.*. .: .:. : . :: * . . : *: . . * : . : . :* *. :: : ..* : : .*. .: : * : .: . . * .: . * :. . . * . .: .. : : : :*. ::*::. * ** : . :: *: : :: . *:*. . : . : :.:*::: :: *:: . : .: . ::* * . : . : : : .. :* : :* : :* ::** * :. . . :*. :: .: ... :: :: . : * :** .: .:* * . .* :: : :. : . . ** :: .* :: : : * .** : : : * :*: . . .: *: *:.**.:*:. **:: *::::.. : : *::**:*::.:. : ::: .. . :: : . . : : :::::*: :. :.:* * * :*:::*. : :: ..** ::: : .: . * : :: * : :: :.* :: . :: . ::* *: :*. * * ** * *:. *:.: : .* . . .: ::: *:.. ***:.. . :**::*.:* . : : * : :.: :::: :: . :*:. ::*.: :: * .*:* :*:*: *::::.** ::: . : : *. *.::* ::::* : .*: *.:...::* : : *::: .:* :. ... .* .* . :: :** ::. :..*::: **:* *: : :.* :: : :: *. :* .: 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:.:.:**********.. **.:*::**. * *: :::*:*:*********:*: .***:***: * * * ::***::********:*: :*: *** ******* *** ****.:*:********.****::*********.* :* **:***:: : . : **::**.*** :**: :**.*********.: *: **::* ::: . : : ** .*::*:****:.***:* .* :*:: :*. ::. . : :*:: **::* . * .**:*:*******:**:****:***************** ::***** *: .:**: **:**:*********:*:***.**::*****:.*:* :*********:*******:***************: *:* .: :************************ .*.*.:*:*:*:*****. * ::: :: :**.: ::*: :.::********.****:* .*.*.: * ::::.******** :*.::.*. * : : :. ..:::*:**: : :.****:** * .** *:*: :*. : ***:***.**:****:*:***:.*:* *****: *:**** ***************::.**:*******:******** ***:*:*::: ***:**:** ****** :* .* * **: ::::* *..:* .:: . ::* :*.*:*:*..****.:**.::: . .:* : :* * *: :**:*:***:*:**. .:*. :: *.: *:: * *:*: *:* **. . : * *:****.***. * * . : : : :* *:*:*** ** :.::. * :.. ::*::* *:::. . :*:***** .:*** : : : ::. *:*****:* * *:**:**:* *.****** * : ::. : :.****: : :* : *::: . . *.: *::**.* **.:*** .*. :*.*.*: :**.** : .: :: :: *: *:*. . :*: : * *::****.**:*****: :*. :**:** :: **** ** * . . ::*: *:.* :*:: *. . *: : .*:** *: * :.** ::::: .:* ::**. .. : ** :: :: : :* * **.*::**:::*.:.:* .** *: .* *: . :* .*:* * * :..*::.:*::* : **:: : : ::. .. : *.. . * .. .:** *::*. :* : * : ... :. ::: *. *: *:*:*:*:: :. .: *. : *. :. ..:.:: : :: * : :: : .. *:*:: * :* : .:*..***:**.* *:: : ** * *.:::.*:** : *:::* .: : **:**:::** :*:.*: * ..::: *:***: :* . :*:.*:** : **::**:***: ***::**:::** :**.** *::* : .**:**** **:.*::*:: . * :: . .:: : :*. :. ..*:* .:**:*:*** ** :**: ::.: : ::::*: .* :***:****:* *. * **:*:*.: . . :*:** .:: : : . :**:* *:.*:*:**. .::. .. .: ** :. .. :.* : *::: :*: : * : :*** :* . :.*.* : .: * : .. . *: .. .* *: :*..::: .* :.::.** *:* * .*. *******:* .*: * . .: * *...*.* *****:** * * * :** .* * ** .. ***:.**:** * . :* . . : ** ***:* * : *.: :*:* * * ** **: :*:* * * * . *:: *:**:: :*: ***: *::** . *::**: * : *: *:*:*..*:.*:: *** :* :** :. . * :** ::** :.: ::* .*:* *:** :* :. ** : ** **:* : ...: :* .:: :. ::*: :*: :::..** ** .:.:*..: * . :* .*: ::. :.::* *:* * * *::. * **.:* ..*:.:: :..*.* : ::. :: . **:: **:*:**:* :::* :* ..:* : *:*:: **: ****: . . : *:. *: .:: ::: *:.*. . . :. * . * ... : *:.* . ", "identical_positions": 1431, "similar_positions": 1644, "identity": "26.49%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110825-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7Z4K8-1", "uniprot_id": "TRI46_HUMAN", "id": "Q7Z4K8-1", "name": "Tripartite motif-containing protein 46", "aln": "MAEGEDMQTFTSIMDALVRISTSMKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPASTPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQVIMFPCPACQGDVELGERGLAGLFRNLTLERVVERYRQSVSVG-GAILCQLCKPP-PLEATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDH-KEEVTHYCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLTYILGNQDTVQTQICELEEAVRHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEECQQERLARLSAQIQEHRSLLDGSGLVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRPAASSSFRHCQLDVGREMKLLTELNFLRVPEAPVIDTQRTFAYDQIFLCWRLPPHSPPAWHYTVEFRRTDVPA--------QPGPTR-------WQRREEVRGTSALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPVLHFFLDSRWGASRERLAISKDQRAVRSVPGLPLLLAADRLLTGCHLSVDVVLGDVAVTQGRSYWACAVDPASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDATVEASPPFAFLTIGMGKILLGSGASSNAGLTGRDGPTAGCTVPLPPRLGICLDYERGRVSFLDAVSFRGLLECPLDCSGPVCPAFCFIGGGAVQLQEPVGTKPERKVTIGGFAKLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TNM2-1", "uniprot_id": "TRI46_MOUSE", "id": "Q7TNM2-1", "name": "Tripartite motif-containing protein 46", "aln": "MAEGEDMQTFTSIMDALVRISTSMKNMEKELLCPVCQEMYKQPLVLPCTHNVCQACAREVLGQQGYIGHGGDPSSEPTSPASTPSTRSPRLSRRTLPKPDRLDRLLKSGFGTYPGRKRGALHPQTILFPCPACQGDVELGERGLSGLFRNLTLERVVERYRQSVSVG-GAILCQLCKPP-PLEATKGCTECRATFCNECFKLFHPWGTQKAQHEPTLPTLSFRPKGLMCPDH-KEEVTHYCKTCQRLVCQLCRVRRTHSGHKITPVLSAYQALKDKLTKSLAYILGNQDTVQTQICELEETIRHTEVSGQQAKEEVSQLVRGLGAVLEEKRASLLQAIEECQQERLSRLSAQIHEHQSLLDGSGLVGYAQEVLKETDQPCFVQAAKQLHNRIARATEALQTFRPAASSSFRHCQLDVGREMKLLTELSFLRVPEAPVIDTQRTFAYDQIFLCWRLPPHSPPAWHYTVEFRRTDVPA--------QPGPTR-------WQRREEVRGTSALLENPDTGSVYVLRVRGCNKAGYGEYSEDVHLHTPPAPVLHFFLDGRWGASRERLAISKDQRAVRSIPGLPLLLAAERLLTGCHLSVDVVLGDVAVTQGRSYWACAVDPASYLVKVGVGLESKLQESFQGAPDVISPRYDPDSGHDSGAEDAAVEALPPFAFLTIGMGKILLGSGASSNAGLTGRDGPTASCTVPLPPRLGICLDYERGRVSFLDAVSFRGLLECPLDCSGPVCPAFCFIGGGAVQLQEPVGTKPERKVTIGGFAKLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M2B4G5-1", "uniprot_id": "A0A8M2B4G5_DANRE", "id": "A0A8M2B4G5-1", "name": "", "aln": "MAD-AELQTFTSIMDALVRISSNMKSMERELHCPVCEEMVKQPIVLPCSHSVCVLCAAEVLVQRGYP--PPELPPEPNTPTSSPLTRSPRQNRRPPPKTDRLDRVIRTVCGTHPGRRRKDTPPILMLFPCPTCRRDVELGERGLADCLRNLTLERIVERYRHTVSLGTMAIMCQFCKPPQTLEATKGCADCRSNFCNECFKLYHPWGTPRAQHEHILPTHSFRPKVLVCVEHEQERLQFYCRSCQRLLCSLCKLRRAHSGHKIMPIALAYQTLKDKITKEMNYILANQDSVQAQITQVESGIAQTEVNSAVVKEQLSQCVNELRAVLAERQGALAMCLEGSRAQRAAALNAQLSEKQSLLENAGLLTYTQELLKESDQSCFVQAARVTHNRLVKAIENLQHFSLSADPSFRHFQMDVSRELKALSSMDFIQAPLAPVIDTQKTLAYDQLYLCWRLPQDSAPAWHYSVEFQRKVGGAGAVWGRVWSEGSSGSNGTHCSWQRLDDVGGTSAVIDKLEMDSVYVLRVRGCNKAGFGEYSEEVYLHTTPAPVFITF---------------KAYSICPIIHSYNLLIFADL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: ::**************:.**.**:** ****:** ***:****:*.** ** *** *:** : ..**.:*:*:* ***** .**. **.*****:::: **:***:* * ::****:*: *********:. :*******:*****::**:* **:**:**** .*******::**:.********:***** :**** *** ***** *:* :* :*.: .**::****:*.**::**:****** *: ***:****:**.: ***.***:**:** ::*. : :***.. .**::** *. * *** *::.:* .:* .: :* : *.**: *::***:.:**: *:**:***:**.******: ***:.:* * ** * :*..**** *:**.**:* *:.:.*::.* *******:*:****::****** .*.*****:***:*. * . *.: *** ::* ****:::: : .**************:*****:*:***.****: * * : . **: *: ", "identical_positions": 316, "similar_positions": 148, "identity": "40.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110825-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O95405-1", "uniprot_id": "ZFYV9_HUMAN", "id": "O95405-1", "name": "Zinc finger FYVE domain-containing protein 9", "aln": "MENYFQAEAYNLDKVLDEFEQNEDETVSSTLLDTKWNKILDPPSHRLSFNPTLASVNESAVSNESQPQLKVFSLAHSAPLTTEEEDHCANGQDCNLNPEIATMWIDENAVAEDQLIKRNYSWDDQCSAVEVGEKKCGNLACLPDEKNVLVVAVMHNCDKRTLQNDLQDCNNYNSQSLMDAFSCSLDNENRQTDQFSFSINESTEKDMNSEKQMDPLNRPKTEGRSVNHLCPTSSDSLASVCSPSQLKDDGSIGRDPSMSAITSLTVDSVISSQGTDGCPAVKKQENYIPDEDLTGKISSPRTDLGSPNSFSHMSEGILMKKEPAEESTTEESLRSGLPLLLKPDMPNGSGRNNDCERCSDCLVPNEVRADENEGYEHEETLGTTEFLNMTEHFSESQDMTNWKLTKLNEMNDSQVNEEKEKFLQISQPEDTNGDSGGQCVGLADAGLDLKGTCISESEECDFSTVIDTPAANYLSNGCDSYGMQDPGVSFVPKTLPSKEDSVTEEKEIEESKSECYSNIYEQRGNEATEGSGLLLNSTGDLMKKNYLHNFCSQVPSVLGQSSPKVVASLPSISVPFGGARPKQPSNLKLQIPKPLSDHLQNDFPANSGNNTKNKNDILGKAKLGENSATNVCSPSLGNISNVDTNGEHLESYEAEISTRPCLALAPDSPDNDLRAGQFGISARKPFTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKEARVCVICHSVLMNAQAWENMMSASSQSPNPNNPAEYCSTIPPLQQAQASGALSSPPPTVMVPVGVLKHPGAEVAQPREQRRVWFADGILPNGEVADAAKLTMNGTSSAGTLAVSHDPVKPVTTSPLPAETDICLFSGSITQVGSPVGSAMNLIPEDGLPPILISTGVKGDYAVEEKPSQISVMQQLEDGGPDPLVFVLNANLLSMVKIVNYVNRKCWCFTTKGMHAVGQSEIVILLQCLPDEKCLPKDIFNHFVQLYRDAL-AGNVVSNLGHSFFSQSFLGSKEHGGFLYVTSTYQSLQDLVLPTPPYLFGILIQKWETPWAKVFPIRLMLRLGAEYRLYPCPLFSVRFRKPLFGETGHTIMNLLADFRNYQYTLPVVQGLVVDMEVRKTSIKIPSNRYNEMMKAMNKSNEHVLAGGACFNEKADSHLVCVQNDDGNYQTQAISIHNQPRKVTGASFFVFSGALKSSSGYLAKSSIVEDGVMVQITAENMDSLRQALREMKDFTITCGKADAEEPQEHIHIQWVDDDKNVSKGVVSPIDGKSMETITNVKIFHGSEYKANGKVIRWTEVFFLENDDQHNCLSDPADHSRLTEHVAKAFCLALCPHLKLLKEDGMTKLGLRVTLDSDQVGYQAGSNGQPLPSQYMNDLDSALVPVIHGGACQLSEGPVVMELIFYILENIV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2A8R0-1", "uniprot_id": "A2A8R0_MOUSE", "id": "A2A8R0-1", "name": "Zinc finger FYVE domain-containing protein", "aln": "MENYFQAEAYNLDKVLDEFEQNEDETVSPTLLDTKWNKILDPSSHPLSFNPALASVNEPTVS-ETGPQLKVFSLAGSAPLTKEDKDPCANGQDCSLNPETDTMWIDENAVTEDQLIKRNYNQDDQFSAVEVGEEKCGSLTCLPDEKNVLVVAVMHNCDKRTLQSDLQDCNNYNSQSLMNSFSCSLDNETRQTDQFSFSMNGSTEKGINSEKQMDALNKPKPERDSVNHLCAASSNSATSISSPSQLKDGENVGRDPSTSTVTSLAVN---SSQGMDGGPAIKQQGNYMPDEDLSGMNSSSRTDLGISNSFSHSSGELLIKTEPAEERTAEDSLPSDLSLNLKPDTPALSGRDN-CEQSSDCLGSSETRADEDEG-------------------NDSQ-MTNWKLTKLNEMSDSQVNEENQMALQSNQPEDTN--SGGECVGMADSDLDFKGTCMNESEGYDFSTVNDAPAANSLSNSCDSYGMQSPIVSFVPKTLPSKEDSVTEEKEIEESKSECYSNIYEQRGNENAEGSGLLLNSTGNVMKKNYLHNFCSQIPSVLGQSSPK-IANLQSISVPFGGARPKQPSNLKLQIPKPLSDHLQNDLPANNGNNSKNKNDVLGKAKLGENSAVNACSATLGNISVTDTNGEHLETYEAEISSRPCLALAPDSPDNDLRASQFGISARKPFTTLGEVAPVWVPDSQAPNCMKCEARFTFTKRRHHCRACGKVFCASCCSLKCKLLYMDRKEARVCVICHSVLMNAQAWENMMSASSQSPNPNNPAEYCSTIPPLQQAQASGALSSPPPTVMVPVGVLKHPGTEVPQPREQRRVWFADGILPNGEVADAAKLTMNGTSSAGTLAVSHDPVKPVATSPLPTEADTSLFSGSITQVGSPVGSAMNLIPEDGLPPILISTGVKGDYAVEEKPSQISVMQQLEDGGPDPLVFVLNANLLSMVKIVNYVNRKCWCFTTKGMHAVGQSEIVILLQCLPDEKCLPKDIFNHFVQLYRDAL-AGNVVGSLGHSFFSQSFLGSKEHGGFLYVTSTYQSLQDLVLPTPPYLFGILIQKWETPWAKVFPIRLLLRLGAEYRLYPCPLFSVRFRKPLFGETGHTIMNLLADFRNYQYTLPVVQGLVVDMEVRKTSIKIPSNRYNEMMKAMNKSNEHVLAGGACFNEKADSHLVCVQNDDGNYQTQAISIHNQPRKVTGASFFVFSGALKSSSGYLAKSSIVEDGVMVQITAENMDSLRQALREMKDFTITCGKADAEDPQEQIHIQWVDDDKTVNKGVVSPIDGKSMESITNVKIFHGSEYKANGKVIRWTEVFFLENDDHHNCLSDPADHSRLTEHVAKAFCLALCPHLKLLKEDGMTKLGLRVTLDSDQVGYQAGSNGQPLPSQYMNDLDSALVPVIHGGACQLSEGPVVMELIFYILENIA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3BDK8-1", "uniprot_id": "A0A8M3BDK8_DANRE", "id": "A0A8M3BDK8-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRQAVTATLSVWGE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RRFGYSTLKDSSESLLDERK---LRPG----------------------------------------------------------------------LKEDSVIEEKERAENEQE--------------------------------------QVEAVLGP-----------------------PS-------SPVEDTHQS----------------------GTTEPSDAMLESCQDQKTSDGMEASLVSGPKNIDSG--------------RKGSLGALPVQRCSSLGTTAPQWVPDSQAPACMKCGSKFSFTKRRHHCRACGKVFCVVCCDLRYKLTHLGGKEGRVCVTCHSTLINRTLRK-----------------------------------------------------------DQKKVWFADNVLPQSESRSAN-------SSPIHRSVSHTQSAGLAQADVSDLRAADEVSG--------LSSNTKPTPPKDLPPILTSTGVKGDYTLEEKRTESSLLEELERGLAEPLVFVLNANLLAVVKIVSYVNRRCWCVMSKGMHAVGQPEVVILLQCLPEEKRFPTDIFNHFIQIYWDAQTAGKLLNHLSHSLVSRGFLGNNEHAGFVYVRPTFQSLEGLPLPAPPFLFGLLMLRAEVPWAKAFPLRLMLRLGAEYRFYPCPLFSVRFREPLFGPVNNSIMRLLVDFRFYRYTLPTVPGLVVDLEARSTCIRIPKTHHPELLKALNKSNERVLALGACFNEQADSHLICVQTADGQYQTQAISIHSQPRRVTGSCFFVFSGALKPSSGYLAKSSIVEDGLMVQITMETMAELRRCLRDMKDFTVTCGKLHPAERQEYVHIQWQDEEPRFNKGIVSPIDGKSMESLTNIKTHQRLEFRANGKLIRWTEVYYLLKDQHPNGLNNHTSHNRLTERLARAFCLALCQSLCLLKEDGMTKLALRVILDGQKMEFLAGSNGQRLPAPYQDCLNQSLMSVVQSNSQYQGLAACQLELIFYILEDTS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: ::*: . .: :.*:: .:* ::*.: *: . ***** **** *.:.* *: :*** ** .*:.* *. * ... :. : : . * * : :*.: * ..:* . : ::** .** ******** **** ::*:****************. **.*: ** ::. **.**** ***.*:* : :*::*****.:**:.* .* **. :*** :: : :. .** :.* : * ..***** ********::*** :: *::::** * .:***********::****.****:***. :********.*:********:** :*.******:*:* ** **:::. *.**:.*:.***.:**.**:** .*:***:.* **:**:***:*: : *.****.**:**:********:***********:**** ..::**.**.*** *:****.* *****:*.*.*.*:**..:: *::**:*****:*** ******:*****:***. **:*********.***:***:.*********.**************:***** *.* .**:.**:*****:**** .. : ** :**** *:: ..**:**********::**:* .: *::****:******::* :*:: * *.: :.*.****::*:******* * **********.*** **.::: : ****** **: * : *:.:*:.*::..: . .. :********: ", "identical_positions": 428, "similar_positions": 223, "identity": "30.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110830-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3C2P8-1", "uniprot_id": "SPRE2_RAT", "id": "Q3C2P8-1", "name": "Sprouty-related, EVH1 domain-containing protein 2", "aln": "MTEETHPDDDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHP--EGNGRSGFLIHGERQKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGSTTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREPNTRTISSPTSCEHRRIYTL----DPYPMDLYHPDQRLP--RSYPQVTFPEDDEEIVRINPREKIWMTGYEDYRHAPVRGKYLDS----TEDADS-YVRFAKGEVPKHEYTYPYVDSSDFGFGED-PKG---NVIKTQP----PRAKSRRRKENGERSRCVYCRDMFNHEENRRGHCQDAPDAVRTCIRRVSCMWCADSMLYHCMSDPEGD-YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACHHCGVMCRCCGGKHKAAA---------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q924S7-1", "uniprot_id": "SPRE2_MOUSE", "id": "Q924S7-1", "name": "Sprouty-related, EVH1 domain-containing protein 2", "aln": "MTEETHPDDDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHP--EGNGRSGFLIHGERQKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGSTTSSSTLHNEAELGDDDVFTTATDSSSNSSQKREPTTRTISSPTSCEHRKIYTL----DPYPMDHYHPDQRLP--RSYPQVTFPEDDEEIVRINPREKIWMTGYEDYRHAPVRGKYLDT----TEDADS-YVRFAKGEVPKHEYTYPYVDSSDFGFGED-PKG---SVIKTQP----PRAKSRRRKENGERSRCVYCRDMFNHEENRRGHCQDAPDAVRTCIRRVSCMWCADSMLYHCMSDPEGD-YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACHRCGVMCRCCGGKHKAAA---------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z698-1", "uniprot_id": "SPRE2_HUMAN", "id": "Q7Z698-1", "name": "Sprouty-related, EVH1 domain-containing protein 2", "aln": "MTEETHPDDDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHP--EGNGRSGFLIHGERQKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGSTTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREQPTRTISSPTSCEHRRIYTLGHLHDSYPTDHYHLDQPMP--RPYRQVSFPDDDEEIVRINPREKIWMTGYEDYRHAPVRGKYPDP----SEDADSSYVRFAKGEVPKHDYNYPYVDSSDFGLGED-PKGRGGSVIKTQP----SRGKSRRRKEDGERSRCVYCRDMFNHEENRRGHCQDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGD-YTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACYHCGVMCRCCGGKHKAAA---------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T5I8-1", "uniprot_id": "A0A8N7T5I8_DANRE", "id": "A0A8N7T5I8-1", "name": "Sprouty-related, EVH1 domain-containing protein 2", "aln": "MTEESHPDDDSYIVRVKAVVMTRDESSGGWLAQEGGGLSRVGVCKVVPADLELLGRNGFLIFGERLKDKQMILQCFLKKDLVYTKATPTFHHWRVDNRKCGLSFQSPADARAFDRGVRKAIEDLTEGSTTSSSTLQNEAELGDDDVFTNATDSSSNSSQKRETSMQTLAPISFSEPHHCILGHLYDQHRHSDRYYLEQTVPMFQCSRHVRFHEEEEEIVRINPRERSWLTGYEDYRHATTATRTKPL----RPDVTDAYVHLAKSEPPKHDYTYSYPLSGDGHVSRDGKTGIGGGVVTGQPRALTAKWLPRRVEDSRERLRCVYCQNMFSPSENGRGRCQEAPDPVQTCIRRVSFMWCADSLLYHCMSDPEGD-YSDPCSCDASEERFCLRWLALLGLSLLAPCMCCYVPLRACYHCGVACHCCGGKHKATG---------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KG11-1", "uniprot_id": "A0A0B4KG11_DROME", "id": "A0A0B4KG11-1", "name": "", "aln": "---MTEGHESDFLVTVRAQVMTRDESTEGWLPLAGGGLANVSIRKRARLS-PLASGHDYIIYGQRISDQSVILSCVINRDLKYYKVMPTFHHWRAGKQRNGLTFQTAADARAFDKGVLRAYNELIDGLAKSNPTIICPPLTKYDSVGEDDVFMTLDLPVESESLQKIHSSPEGSEKSHKSVSN--NSDSEKLPPPPIHYISTDKTSATTSPPDAPPASAAPSPATAGQIAASENYSYVTLTAVHHDYNYPVVDQPVGAQVLNARRESISALKKRNALEAAQAMAAAQTAAGGGLACRDGGSGKPLHKPNVSDILKKETRLRCRYCHELYSEDFNRRGACEYAPDAFRSGYECISGMGCARCMIYHCMSDAEGETAQHPCDCSASEAGCSKRWLGLAILSLFVPCLWCYPPLRACHLAGIHCGLCGGQHKPHVXHLEARLQGQHDDDPRPRSEFHYHHSEQSIMNSAKRPWGAKQKQSQQSQQSQRHFYNWELSHSLGAPQHQTPPYLMQSTGRKAPQNDYGRLLF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .:..::* *:* *****:*: **:. ***::.*.: * . .::*.*:* .*: ::*.* :.:** * *. ******:..::: **:**:.*******:** :* ::* :* :.*..*: . *.* . : : . : * : :. .* : . : :. : . : . .* ::. *:* :.. : . * *: * . . :.: . : * . : .. * ** **::::. . * ** *: ***..:: . :* * ** .::******.**: .**.*.:*: . **:.* **::.**: ** *****: .*: * ***:**. ", "identical_positions": 110, "similar_positions": 129, "identity": "20.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110901-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZX02-1", "uniprot_id": "D3ZX02_RAT", "id": "D3ZX02-1", "name": "Fascin", "aln": "MP--------TNG--LHQVLK---IQFGLVNDADRYLTAESFGFKVNASAASLKRKQIWVLEPDPGQGTAVLFRSSHLGRYLSAEEDGRVACEMDHPGRDCRFLVLPQPDG--RWVLQSEPHGRFFGGVEDRLSCFATAISPAELWTVHLAIHPQAHLLSVSRRRYVHLCLQEDEMAADGDMPWGVDALLTLIFQS---RRYCLKSYDSRYLRSDGRLVWEPEAHACYTLEFKAGKLAFKDCDGRYLAPVGPAGTLKAGRNTRPGKDELFDLEQSHPQVVLVA-ANHRYVSVRQGINVSANQDEELDHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIQATATQVSANTMFEIEWHG-RRVALKASNGRYVCMKKNGQLAAISDFVGEDELFILKLINRPILVLRGLDGFVCHRR-GSNQLDTNRSTYDVFHLS-FRDGAYQIRGRGGGFWYTGSHGSVCSDGDLAED-FLFEFRERGRLAIRALSGKYLRGGASGLLRADADLPTGEALWEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q32M02-1", "uniprot_id": "FSCN2_MOUSE", "id": "Q32M02-1", "name": "Fascin-2", "aln": "MP--------TNG--LHQVLK---IQFGLVNDADRYLTAESFGFKVNASAASLKRKQIWVLEPDPGQGTAVLFRSSHLGRYLSAEEDGRVACEMDQPGRDCRFLVLPQPDG--RWVLQSEPHGRFFGGIEDRLSCFATAISPAELWTVHLAIHPQAHLLSVSRRRYVHLCLQEDEMAADGDMPWGVDALVTLIFQS---RRYCLKSYDSRYLRSDGRLVWEPEAHACYTLEFKAGKLAFKDCDGRYLAPVGPAGTLKAGRNTRPSKDELFDLEQSHPQVVLVA-ANRRYISVRQGINVSANQDEELGHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIQATATQVSANTMFEIEWHG-RRVALKASNGRFVCMKKNGQLAAISDFVGEDELFTLKLINRPLLVLRGLDGFVCHRR-GSNQLDTNRSTYDVFHLS-FRDGAYQIRGRGGGFWYTGSHGSVCSDGDLAED-FLFEFRERGRLAIRALSGKYLRGGASGLLRADADLPVGEALWEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14926-1", "uniprot_id": "FSCN2_HUMAN", "id": "O14926-1", "name": "Fascin-2", "aln": "MP--------TNG--LHQVLK---IQFGLVNDTDRYLTAESFGFKVNASAPSLKRKQTWVLEPDPGQGTAVLLRSSHLGRYLSAEEDGRVACEAEQPGRDCRFLVLPQPDG--RWVLRSEPHGRFFGGTEDQLSCFATAVSPAELWTVHLAIHPQAHLLSVSRRRYVHLCPREDEMAADGDKPWGVDALLTLIFRS---RRYCLKSCDSRYLRSDGRLVWEPEPRACYTLEFKAGKLAFKDCDGHYLAPVGPAGTLKAGRNTRPGKDELFDLEESHPQVVLVA-ANHRYVSVRQGVNVSANQDDELDHETFLMQIDQETKKCTFYSSTGGYWTLVTHGGIHATATQVSANTMFEMEWRG-RRVALKASNGRYVCMKKNGQLAAISDFVGKDEEFTLKLINRPILVLRGLDGFVCHHR-GSNQLDTNRSVYDVFHLS-FSDGAYRIRGRDGGFWYTGSHGSVCSDGERAED-FVFEFRERGRLAIRARSGKYLRGGASGLLRADADAPAGTALWEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YWM1-1", "uniprot_id": "A0A8M6YWM1_DANRE", "id": "A0A8M6YWM1-1", "name": "Fascin", "aln": "MS--------TNG--ISAALK---LQFGLINHENRYLTAEAFGFKINASGNSMKKKQIWTLEQDPD--SQVVFLRSHLGRYLSSDKDGKVRCEEEVPNTDCRFLIVMQSDG--RWALQSEPYLRYFGGSEEYLSCFAQTIGESELWALHLALHPQANLLSVARKRYAHLSTQEDEISMDSNIPWGVDSLITLVYLE---GKYSLKTCDNRFLKNDGKLVMEHGPNTSFTLELKSGKLAFKDCEGKYLSPNGPTGTLKSGRCTRPGKDELFDLEESHPQVVFQA-ANKRYVSIRQGVCISANQDDETDMETFQMEIDKETKKCMFRTNGGNYWTLVTHGGILSSATEIEENTMFDIEWLG-RRIALKASNGKYVCTKKNGQLAAVSDSLGEDEQFVLKLINRPILVLRGENGFVCHHK-NSNTLHGSRSFYDIFTLL-FSDGGYQIKSGNQKFWYVSSSGLVCTDGDKPED-FFFEFVEYGRVGIKAQNGKYLRGDQGGTLMGDGLSVNASSLWEH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24524-1", "uniprot_id": "SING_DROME", "id": "Q24524-1", "name": "Protein singed", "aln": "MNGQGCELGHSNGDIISQNQQKGWWTIGLINGQHKYMTAETFGFKLNANGASLKKKQLWTLEPSNT-GESIIYLRSHLNKYLSVDQFGNVLCESDERDAGSRFQISISEDGSGRWALKNESRGYFLGGTPDKLVCTAKTPGASEFWTVHLAARPQVNLRSIGRKRFAHLSESQDEIHVDANIPWGEDTLFTLEFRAEEGGRYALHTCNNKYLNANGKLQVVCNEDCLFSAEYHGGHLALRDRQGQYLSPIGSKAVLKS-RSSSVTRDELFSLEDSLPQASFIAGLNLRYVSVKQGVDVTANQDEVGENETFQLEYDWSAHRWALRTTQDRYWCLSAGGGIQATGNRRCADALFELIWHGDGSLSFRANNGKFLATKRSGHLFATSESIEEIAKFYFYLINRPILVLKCEQGFVGYRTPGNLKLECNKATYETILVERAQKGLVHLKAHSGKYWRIEGE-SISVDADAPSDGFFLELREPTRICIRSQQGKYLGATKNGAFKLLDDGTDSATQWEF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :** : : :**:* .:*:***:****:**.. *:*:** *.** . :: ***.:*** :: *.* ** : . ..** : . ** **.*:.*. ::** : * * * : . :*:*::*** :**.:* *:.*:*:.**. :**: *.: *** *:*.** : :*.*:: :.::*. :*:* :: * :.*:**::* :*:**:* *. ..**: * : :****.**:* **. : * * **:*::**: ::****: *** :: * .::: : :. . ** * : *** ::... :::*:: * * ::::*.**:::. *:.*:* * *: : : * : *****:***: :*** :: .. *. .:: *: : : .* :::. . :* . :. *.: ..* *.:*: * *: *:: .**** . .* : . : **.", "identical_positions": 158, "similar_positions": 174, "identity": "30.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110908-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66HA5-1", "uniprot_id": "C2D1A_RAT", "id": "Q66HA5-1", "name": "Coiled-coil and C2 domain-containing protein 1A", "aln": "-MHKRNGPQAPPGRGAVTARQLGLLVDFSPDGLMIPEDGVNDEELEAEFLALVGGQP-----QALEKLKGKGPLPMEAIEKMARLCMRDLDEDEE-GTDED-VEADEDLLAELNEVLGEERKAVEPAMP-----------VVQPKPSSPNPGIEATLQERLILYQSAVESARQAGDSAKMRRYDRGLKTLENLLVSAKKGNTINEADIPPPVASGKGPAIGHSHTHTTSHLAPVS-------------PPAPEPSVTLEAPST--TAQTS----AKPQLSPDPCSP----LARLQSLQHEYKVAALRAKHQDDTATAARYLRVSKSFDPVLEALSRGELVDLSRLPPPPDQLSP-----EPPLPAAQPVTPASTLTRPEVPQ-----PPKNLLEALEQRMERYHVAAAQAKAKGDQRKARMHERIVKQYQDAIRAHKAGRAVDVAELPVPPGFPPIQGLESAEPSQQSLVGVLETAMKLANHEEGSDEEEEE---TPKK-NTPAASTAQPKASPSRAPPSGPAPAGKAASKGTST------RAQQQLAFLEGRKKQLLQAALRAKQKNDVEGAKMHLRQAKGLEPMLEASRNGLPVDIAKVPPAPVNKD----DFVLVQRPGPGMSQEAVRRYGELTKLLRQQHEMCLNHSTQFTHLGNIAETIKFEKLAEDCKRSMDTLKQAFARSLPTPAARFEQRTFSVIKIFPDLSNNDMLLFIVKGINLPTPPGLSPSDLDAFVRFDFPYPNVEEAQKDKTSVIKSTDSPEFKEQFKLCINRGHRGFRRAIQTKGIKFEVVHKGGLFKTDRVLGTAQLKLDTLETACEVHEILEVLDGRRPTGGRLEVMVRIREPLTAQQLETTTERWLVIDHIPAAVPT-VTGPKAKVP-------LIPASSKEAGNRSSR-----------PLHSLSVLAFDQERLERKILALRQARRPVPPEVAQQYQDVVQRSQWQRAQLEQGGAALRREYASHLERQLHFYTEAARRLGYDGSREAAKEALYRRNLVESELQRLRR------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K1A6-1", "uniprot_id": "C2D1A_MOUSE", "id": "Q8K1A6-1", "name": "Coiled-coil and C2 domain-containing protein 1A", "aln": "-MHKRNGPQAPPGRGAVTARQLGLLVDFSPDGLMIPEDGINEEELEAEFLALVGGQP-----QALEKLKGQGPLPMEAIEKMARLCMRDLDEDEE-GTDEDDVEADEDLLAELNEVLGEEQKAVEPLMP-----------VAQPKPSGPNPGVEATLQERLTLYQSALESARQAGDSAKMRRYDRGLKTLENLLVSAKKGNIINEADIPPPVASGKGAAAGHSHTQATSQLASVS-------------PPAPESSGTLEAPST--TTPTS----AKPQLPPDPCSP----LARLQSLQHEYKLAALRAKHQDDTATATRHLRIAKSFDPVLEALSRGELVDLSRLPPPPDQLSP-----EPPLPAAQPLTSASTLTRPEVPQ-----PPRNLLEALEQRMERYHVAAAQAKAKGDQRKARMHERIVKQYQDAIRAHKAGRAVDVAELPVPPGFPPMQGLESAEPSQQSLVGVLETAMRLANHDEGSDDEEEE---TPKKQNTPAASTTQLKSSPSKAPPSGPAPAGKAAPKGTSN------RAQQQLAFLEGRKKQLLQAALRAKQKNDVEGAKMHLRQAKGLEPMLEASRNGLPVDIAKVPPAPVNKD----DFVLVQRPGPGLSQEAVRRYGELTKLLRQQHEMCLNHSTQFTHLGNIAETIKFEKLAEDCKRSMDTLKQAFARSLPTPAARFEQRTFSVIKVFPDLSNSDMLLFIVKGINLPTPTGLSPSDLDAFVRFDFPYPNVEEAQKDKTSVIKNTDSPEFKEQFKLCINRGHRGFRRAIQTKGIKFEVVHKGGLFKTDRVLGTAQLKLGTLETACEVHEILEVLDGRRPTGGRLEVMVRIREPLTAQQLETTTERWLVIDHIPAAMPT-VTGPKAKAP-------LIPASSREAGNRSAR-----------PLHSLSVLAFDQERLERKILALRQARRPVPPEVAQQYQDVVQRSQWQRAQLEQGGAALRREYASHLERQLHFYTEAARRLGYDGSREAAKEALYRRNLVESELQRLRR------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P1N0-1", "uniprot_id": "C2D1A_HUMAN", "id": "Q6P1N0-1", "name": "Coiled-coil and C2 domain-containing protein 1A", "aln": "-MHKRKGPPGPPGRGAAAARQLGLLVDLSPDGLMIPEDGANDEELEAEFLALVGGQP-----PALEKLKGKGPLPMEAIEKMASLCMRDPDEDEEEGTDEDDLEADDDLLAELNEVLGEEQKASETPPP-----------VAQPKPEAPHPGLETTLQERLALYQTAIESARQAGDSAKMRRYDRGLKTLENLLASIRKGNAIDEADIPPPVAIGKGPASTPTYSPAPTQPAPRI-------------ASAPEPRVTLEGPSA--TAPASSPGLAKPQMPPGPCSPG--PLAQLQSRQRDYKLAALHAKQQGDTTAAARHFRVAKSFDAVLEALSRGEPVDLSCLPPPPDQLPP-----DPPSPPSQPPTPATAPSTTEVPP-----PPRTLLEALEQRMERYQVAAAQAKSKGDQRKARMHERIVKQYQDAIRAHKAGRAVDVAELPVPPGFPPIQGLEATKPTQQSLVGVLETAMKLANQDEGPEDEEDE---VPKKQNSPVAPTAQPKAPPSRTPQSGSAPTAKAPPKATST------RAQQQLAFLEGRKKQLLQAALRAKQKNDVEGAKMHLRQAKGLEPMLEASRNGLPVDITKVPPAPVNKD----DFALVQRPGPGLSQEAARRYGELTKLIRQQHEMCLNHSNQFTQLGNITETTKFEKLAEDCKRSMDILKQAFVRGLPTPTARFEQRTFSVIKIFPDLSSNDMLLFIVKGINLPTPPGLSPGDLDVFVRFDFPYPNVEEAQKDKTSVIKNTDSPEFKEQFKLCINRSHRGFRRAIQTKGIKFEVVHKGGLFKTDRVLGTAQLKLDALEIACEVREILEVLDGRRPTGGRLEVMVRIREPLTAQQLETTTERWLVIDPVPAAVPTQVAGPKGKAP-------PVPAPARESGNRSAR-----------PLHSLSVLAFDQERLERKILALRQARRPVPPEVAQQYQDIMQRSQWQRAQLEQGGVGIRREYAAQLERQLQFYTEAARRLGNDGSRDAAKEALYRRNLVESELQRLRR------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q7L9-1", "uniprot_id": "A0A8M1Q7L9_DANRE", "id": "A0A8M1Q7L9-1", "name": "Coiled-coil and C2 domain-containing protein 1B", "aln": "-MSRSRNPP-QKGQGAARAKQMGLLLDLAPD-SGLDDSGGNEAELEAELMALMGGGGGGRGGAGGKKPGGKAPVAMEDIERMAALCMKDLDEDGD---EDGDLENDADLLAELNEVLEDDEEEVVRKPPPSPVPPQRSNVAPQPVSQNASGSLESRLQERLDMYQTAINNAKAAGESSKVRRYDRGLKTLQSMLASVKKGKPINEEEIPPPVATGGKSTPATPAEPIREQEAPALPQTANEKPLQDSRPAAPPKPQLLQPPAQRVTALTPETPAISPLTPAQPNAQHSELKASVLSRQREYKLAAIKAKQSGNTEQAKQLYHVSKTLDSVVEAVDRGEMVDLRSLPPPPGDVEV-----PQSNPPQQISKPAAAPAPPAAPANTALSAPRSVAEALQQRMDKYKEAAEAAKSKGDERKARMHQRIIKQYQDAIKAQKAGRPVNLADLPVPPGCPPLQGAESGD---QNLMGVLENAVKLANQDADAEEEEPQKVNIMAHTSCILQPSAQPAVQKSRAPAPPKASSTAGTPTGSTNTPKMGGKAQQQLDFLTMRRQQFIKAALRSKEMKDMQGAAQHLRNAKGLDPMITAAKGGLPVDITKVPAAPVSDE----DYRLSQSRSSAVSPRSAEQYRQLMEQLKQQHEKCLAYSQQFTHMGNIAETARFEKLAEECMNSIDILKKAHAKGRSVPKYHTEERTFNTVKIFPNLTANEMMLYIVKGINLPPPPGGSANDLDASVRFEFPFPSAEEAQKDKTSTVKNTNSPEFKEQFKLNIKRDHRGFRRVVQAKGIKLEVVHKGGLFKNDKVVGSAQLKLEALENQCEIREIVDVLDGRKATGGKLEVRVKIREPLAGSQLQSVTEKWLVLDPLTPSPEKHREQQKDREPEKGREKERAPSPRSKPRNDHDRNHKTSSSPPQYKLHSFSLLHHDKERLEWKINEYKKNRR-DPSEVIKQHMDVCQRLQWQKSYLEKHPAALT-EYENVLRKFVHGLSDSVKTFSNQGNREAAKDALGRLKMVENELESVRKKRAVRD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKJ9-1", "uniprot_id": "C2D1_DROME", "id": "Q9VKJ9-1", "name": "Coiled-coil and C2 domain-containing protein 1-like", "aln": "MFSRKKPEPAKRRQHDLSQFGLTEIPDDFDPSAGYGEDDGGDSDLEAELAAITGGEG-----AKPKPKPKAKLLPASDLDKMIADSLRDVSDDDD----DDNLESDPDLLGELSGIGGLEEAEEEEPVAQPPAASEE---PVQTFLPTTTVDTLSIIKQRLEMYKQAEANAKTAGDSGKARRFGRGLKTLKDLHRQAAAGKSINVDDIPPEVSVKP-IGGQAPPVPAEESPAPST-------------PASPPPVPSRAAPDPP-TPGTP----VEPTTSVAPTSPPNPLVTQMRSRQTDYKAAALQSKRSGDISTALQFLKVVKQFDVVIKMCEDGQEVDLSDMPPPPAEFLEFLKKMQEEAAAEAVAEPTAAPEPTPVAPAPVLAAATNMLEALQQRLEKYQSVEAAAKAENNSGKARRFGRIVKQYEDAIKLYKAGKPVPYDELPVPPGFGPLPTADAAPVAPTPSLPTSPTSPPPTASTSAG--------------GTPSSSSATTPTAPRKAPSPPKPKELTTRTSGNQQK---NNIAEQQMKLLLERQKEFKLAAIEAKKAGEIDQAKEYLKIFKGFDSLLNAASSGLPVDLSTLPVPPSQRDNLEASFAIVSAEECDPTDDICEIGVRMEEQLAKQLMMCKNTRDHHKAMGDVAGMNRFENLALTVQKDLDLVRYSKRKNEPLPKFHYEKRSFNIVHCNTDLTDSELEIVVVRGISYNVAN---PKDVDTYVRVEFPLLN-DESFKTKTNVIRDTSSPDYDERFKVDIQRTNRQFQRIFKRHGVKFEIYSRGGFLRSDTLIGTVNVKLQPLETKCEIHDTYDLMDGRKQVGGKLEVKIRVRNPILTKQMEHITEKWLVLDA--------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . : : : * :.. .: :****: *: ** : :. . :::* .::* .:* : :. :* * ***.**. : :. . *. . . : :::** :*: * .*: **:*.* **:.******:.: . *: *: :*** *: . *. ..:* * *. :. .* . * : : : * * :** **:::*:..: * : :: * :* *:: . *: *** :**** :. .. .::: . .. .. .: ***:**:::*: . **::.:. *** . **:***:***: ***:.* :****** *: :: : . .: : . .:: ::* . . .... *:**: :* *:::: **:.:*: ::: * :*: **::.:: *: .*****::.:* .* . : .: : . : . .: : : :* * :.. :*::: :**:** ..:* :: : :. . * : *:*:*. :: .:*: .:: : :*:**. . . *:*. **.:** . :*: * **..::.*.**::.*:**: *:* :* *:* .: :*:*:*: :**:::.* ::*:.::** .** **::: :::***: .**:*** :::*:*: .*:: **:***:* ", "identical_positions": 185, "similar_positions": 277, "identity": "17.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110909-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86Z14-1", "uniprot_id": "KLOTB_HUMAN", "id": "Q86Z14-1", "name": "Beta-klotho", "aln": "MKPGCAAGSPGNEWIFFSTDEITTRYRNTMSNGGLQRSVILSALILLRAVTGFSGDGRAIWSKNPNFTPVNESQLFLYDTFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSSTNGSSDSYIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWDLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAPGEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSITLGSHWIEPNR-SENTMDIFKCQQSMVSVLGWFANPIHGDGDYPEGMRKKLFSVLPIFSEAEKHEMRGTADFFAFSFGPNNFKPLNTMAKMGQNVSLNLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIRENGFSLKESTPDVQGQFPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLHRVEGVRLKTRPAQCTDFVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVTLYYPTH--AHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLSLHADWAEPANPYADSHWRAAERFLQFEIAWFAEPLFKTGDYPAAMREYIASKHRRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFVMHEQLAGSRYDSDRDIQFLQDITRLSSPTRLAVIPWGVRKLLRWVRRNYGD-MDIYITASGIDDQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAEEKSKPRFGFFTS---DFKAKSSIQFYNKVISSRGFPFENSSSRCSQTQENTECTVCLFLVQKKPLIFLGCCFFS-----TLVLLLSIAIFQRQKRRKFWKAKNLQHIPLKKGK-RVVS----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99N32-1", "uniprot_id": "KLOTB_MOUSE", "id": "Q99N32-1", "name": "Beta-klotho", "aln": "MKTGCAAGSPGNEWIFFSSDERNTRSRKTMSNRALQRSAVLSAFVLLRAVTGFSGDGKAIWDKKQYVSPVNPSQLFLYDTFPKNFSWGVGTGAFQVEGSWKTDGRGPSIWDRYVYSHLRGVNGTDRSTDSYIFLEKDLLALDFLGVSFYQFSISWPRLFPNGTVAAVNAQGLRYYRALLDSLVLRNIEPIVTLYHWDLPLTLQEEYGGWKNATMIDLFNDYATYCFQTFGDRVKYWITIHNPYLVAWHGFGTGMHAPGEKGNLTAVYTVGHNLIKAHSKVWHNYDKNFRPHQKGWLSITLGSHWIEPNR-TDNMEDVINCQHSMSSVLGWFANPIHGDGDYPEFMKTG--AMIPEFSEAEKEEVRGTADFFAFSFGPNNFRPSNTVVKMGQNVSLNLRQVLNWIKLEYDDPQILISENGWFTDSYIKTEDTTAIYMMKNFLNQVLQAIKFDEIRVFGYTAWTLLDGFEWQDAYTTRRGLFYVDFNSEQKERKPKSSAHYYKQIIQDNGFPLKESTPDMKGRFPCDFSWGVTESVLKPEFTVSSPQFTDPHLYVWNVTGNRLLYRVEGVRLKTRPSQCTDYVSIKKRVEMLAKMKVTHYQFALDWTSILPTGNLSKVNRQVLRYYRCVVSEGLKLGVFPMVTLYHPTH--SHLGLPLPLLSSGGWLNMNTAKAFQDYAELCFRELGDLVKLWITINEPNRLSDMYNRTSNDTYRAAHNLMIAHAQVWHLYDRQYRPVQHGAVSLSLHCDWAEPANPFVDSHWKAAERFLQFEIAWFADPLFKTGDYPSVMKEYIASKNQRGLSSSVLPRFTAKESRLVKGTVDFYALNHFTTRFVIHKQLNTNRSVADRDVQFLQDITRLSSPSRLAVTPWGVRKLLAWIRRNYRD-RDIYITANGIDDLALEDDQIRKYYLEKYVQEALKAYLIDKVKIKGYYAFKLTEEKSKPRFGFFTS---DFRAKSSVQFYSKLISSSGLPAENRSPACGQPAEDTDCTICSFLVEKKPLIFFGCCFIS-----TLAVLLSITVFHHQKRRKFQKARNLQNIPLKKGHSRVFS----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IX01-1", "uniprot_id": "A0A0R4IX01_DANRE", "id": "A0A0R4IX01-1", "name": "", "aln": "-------------MCFLSS----------VSFALLLISVCPSESLLQ-------GDSSSVWLQRLNGTHQQTG------VFPRGFLWGIGSSAFPTEGSWDADGKGASIWDHFTLQSPAGAS-----SDSYIQWEEDLKAVQFLGVDFYSFSLSWPRLFPD-LTLNPNPAGVEHYRRLIRKLKELNVEPVVTLFHWDLPQVLQERLGGWLNSSMVGVFADYAEFCFRTFGDEVRFWITMHNPFLVAVQGYGTGAHAPGVKGERGDPFIAAHNLIRAHAKAYHVYDKLFRARQNGKVSISLGSHWVEPLHGQATPTNLELCQKSMEAVIGWFAEPIYGSGDYPESLKSANRGVIPEFSAAERLWVRGSADFFSVAFGPETLRVSRGLARFGQTVALELRSVLVWVQQAYGDPLVLVAESGWFSDASVGVEDTLAIYLNKRFILQVMQAVSVDAVRVFGYTAWSLLDGYEWNQGFSVRRGLFYIDFSQSERRRVPKTSAHFYRQTVRDNGFPDTD-TKHIQARFPCHFQFGVSDSILQVRLHPFSPQFTDPHLYRWNFSGDGSLKPVNGIILHTRPAQCTDFLFIQRHLFLLGVTGSTHYRFSLDWTQLSP----SAGHPETLRFYRCVFSELQRRGIQPVVTLYHPSYRSSSLGLPEALHANGGWRNASTVDAFVRYATFCYREFGALVHMWITINEPNRLTDAYSGSADDRRVVARHLLLAHAKAWRAYDVYFRKQQGATVSLALHADWVEPANPFLESHKNAQQHFLLFELGRFIDPLYNQ-----------------ESSSSTLIGWSDDEREELRGALDFIALNHFTTRLVS-PWAHLKASTPDHGCSLMNDVNWQTSQMGQALVPWGLRRMLGWVKNRYGNRLPIIITASGVDDQAAYHDQLRQSYIRDYLQEALKARELDGVNLRGFYIWKLQDHHD-LQFGLFSSAAHHSRPKASASLYRDIISHRGFIS-SGDPCQSADEDGTSCEICAHIAENKPLLFFSVCVFVSVCMICVLIILSVLRKRRRKRRKTLSVPQRVPVPQRFPMMRVTHRLRH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:*: :* * *. * :* **. ::* :. : : . .**:.* **:*:.*: .****. **:*.****:: ... :**** *:** *::*:**.**.**:*******: . *. *:.:* *: * *:**:***:***** .***. *** * :::.:* *** :**: ***.*::***:***:*** :*:*** **** **: : ..****:**:*.:* *:. **.:*:* :**:*****:** : . :: **:** :*:****:**:*.***** ::. .::* ** **: :**:****:.:***:.:: . :.::**.*:*:**..* *:: *.:* :*::*.***:*: : .*** ***: *.*: **:**: .* :********:****:**::.:: ******:**...::.* **:***:*:* :::***. .: * .::.:***.*.:**::*:*: . ****:***** ** :*: * *:*: *:***:****:: *:::: :*. ***:*:***:.: * * : :.**:****.** : *: .:****:*:: : **** .* .** * .*..** ** :*::*:* **::**********:* *. :.:* .*::*::*** .*: ** :* * .:***:**.**.*****: :** .* ::** **:. * :**:: ***.* : * . ::*::** ********:* . .*:. .:::*:. :* *: ***:*::* *::..* : * ***.*:** * .*::*: *: .*:**.*** :* *.::*:* :** :.:. :**:*:* . :.*:* .:* .:** *: . .. . :.*.* :* .:.::***:*:. *.: : ::**: :::**** .. : :* : ** ", "identical_positions": 415, "similar_positions": 332, "identity": "39.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110913-109", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6NN14-1", "uniprot_id": "ZN729_HUMAN", "id": "A6NN14-1", "name": "Zinc finger protein 729", "aln": "----------------------------------------------------------MPGAPGSLEMGPLTFRDVTIEFSLEEWQCLDTVQQNLYRDVMLENYRNLVFLG---MAVFKPDLITCLKQGKEPWNMKRHEMVTKPPVMRSHFTQDLWPDQSTKDSFQEVILRTYARCGHKNLRLRKDCKSANEGKMHKEGYNKLNQCRTATQRKIFQCNKHMKVFHKYSNRNKVRHTKKKTFKCIKCSKSFFMLSCLIRHKRIHIRQNI------YKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFSSTFTKHKRIHTGETPFRCEECGKAFNQSSNLTDHKRIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTAEKPYKCEDCGKTFNHFSALRKHKIIHTGKKPYKREECGKAFSQSSTLRKHEIIHTGEKP--YKCEECGKAFKWSSKLTVHKVVHTGEKPYK----CEECGKAFSQFSTLKKHKIIHTG-----------------------------------------------------------------------KKPYKCEECGKAFNSSSTLMKHKIIHTGE----KPYKCEECGKAFRQSSHLTRHKAIHTGEKP--YKCEECGKAFNHFSDLRRHKIIHTGK--------KPYKCEECGKAFSQSSTLRNHQIIHTGE--KPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTG-------------EKPCKCEECGKAFKHFSALRKHKVIHTGK-KPYKCEECGKAFSQSSSLRKHEIIHSGEKPYKCEECGKAFKWLSKLTVHKVIHTAEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCE-------ECGKAFNDSSTLMKHKIIHTGKKPYKCAECGKAFKQSSHLTRHKAIHT--GEKPYKCEECGKDFNNSSTLKKHKLIHTR--EKLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGKAFKWSSKLTEHKVIHTGEKPCKCEECDKAFKHFSALR------------KHKVIHTGKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCEECGKAFSQSSILTKHKIIHSVEKPYKCEECGKAFNQSSHLTRHKTIHTGEKPYKCEECGKAFIQCSYLIRHKTIHTREKPTNVKKVPKLLSNPHTLLDKTIHTGEKPYKCEECAKAF---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TT05-1", "uniprot_id": "A0AB32TT05_DANRE", "id": "A0AB32TT05-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKMAFIKEE-------------------------------------SED-----------VKIEETFTVKQ-----------EDLQEQIG---------WFHSQTPTQSYRDLIKDYEES----------------------KEEHHVKIEDKTHLVTDGILKVRDKSC------------------------LTCTQCGKSLASKSKLKTHMRIHTGEKPFT----CYQYGKSFSK-SSLYRHKKIHTG-----------------------------------------------------------------------KKTFTCTQCGKSFNCSSHLNQHIRIHTGE----KPFRCTQCGKSFNCSSHLNEHMMIHTGEKP--FTCTQCGKSFSKSSSLYRHMKIHTGE--------KPYTCTECRKSFSQSSSLNLHMRIHTGE--KPFTCTECGNSFSKS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSLYRHMKIHTGEKPFTCTECGKSFIQSSCLNVHMRIHTG-------------EKPFTCTQCGKSFIHSSHLNQHLMIHTGE-KPFKCPQCGKSFSQS--------------------------------------------------------------------------------------------YLKKHMKIHTGVREYMCLECEKTFITAAELKRHKRIHT--GEKPYKCSQCSKRFAHSGTLKAHQRIHTG--DKL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBR8-1", "uniprot_id": "Q9VBR8_DROME", "id": "Q9VBR8-1", "name": "Zinc finger protein Xfin", "aln": "MLPSDVCRTCAVQNSQLLPLSTCLDKDSSKSYYAVLQELTQIDLENTDDNLPQHICSECWRRMESAYTFVQQARKVHGELLAQLRECLDELPIDIPAEQNIKTEVDLDDGGNKSEVEVDDTEATALELKWQPASGSDREFCSGPESDEDQVEKKSYHLRRSSRKVKHPVESENEECKPSEPSPVKRRRGRPPGPAKSQAMTTDGRHACEVCGKTFSWYRDMQRHARIHFENASYVCDTCGKGFLRKDKYIFHLRCHKKREAKWKALQLGKEWRFAERLYSSGKLKRIECKLCGLSCQRMEELRAHLWDHADTETLVNLRTDSDVVREHFPGLPCDLDNIKKQICVDIADGHLEKYACVVNFHGYELGLSDSDEECDSKESKYHCFVCNMSFNRKHRLMKHTLEDHSQSATTLPWQRCSSCKVGFLCLTMYNKHLNTHCQSKIRRYRCRKCSGRFMWPENLQRHACSHREEKTIASQILCSLCDISLSSLSQLRLHLITHQHDLNGISPEYNSLFFRSFYPDGLNCSISDLAVRIAEDFEVQDFDRYYNASTESGQELDLFESETELSDEETSKTSHICLLCGETSNSLMNLMKHQICLHSDGVAELPCRCDYCGSGFVSKALLQQHRRHRCEKKHSRFHCRICNIRFIWESNYEKHEKTHHNKTKDAEERPTKLKCDQCEKVFIWHKDLNRHKRLHQPQSAAQFDCPHCHRRFHRKDGLKSHLKVHAGNSDYINNQPVVPDVNQEMILARLSRPHGCKLIQCMICLSRHSKISDLRSHLSSHQYELSFAEDRDIPSASKAFYPDLENTLEKDE--------------------------------LAEMIMADVQREFDLDRFISITNEAGLELNLESSETDTESEQEDNHSSLNYPCNLCTTVVKRKHQLYAHQLEEHKWEEAVLVCSNCQTRFVNESLLDHHSRTLCHNPQKLFQCRKCPLRFRWRENLKLHMEVFHMLDELSIQDDLPKVDGDLQCGKCNRSFRMQKDLTRHTLMHGQESNIFRCRWCARRFYRRANLLQHIARHGISVSQLPYAEAILDSYVNPGGRKKVECRVCNVSFPTIAALRLHLETMPAGSHHDYSSLQNYSITNQMGFEMDLYDSETDDEDSRTHIKPPGAPSSYTCNMCQLRCLRKFELYQHQQAMHRMEKISDGCDSCLFKSVCPEIISHHKRTQCENREKQFKCTRCGYKFMWESNLLLHMDLQHVKTEDQELDESKEASGDEPKTEGQVFQCGLCTRKYNRKDRLTAHLKKFHGPDCKPSTAKTPNRPISPKEPKRFLCAFCGKAVSSSSNLIIHMRRHTGEKPFKCEYCTMAFPRSSDLQCHRRTHTGERPHVCTVCQKGFARSYKLQQHMRIHSGERPYKCTYCEKSFTQSNDLTLHIRRHTGERPYQCGVCGERFIQGTALKNHRMQQSHYEEGQESVEPTRRTVLEQFTL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q80VM4-1", "uniprot_id": "ZN579_MOUSE", "id": "Q80VM4-1", "name": "Zinc finger protein 579", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------MDPQPPPPAQGSPPHRDRGRGRGRGRGRGRGRGRGRGGAGAPRAPLPCPTCGRLFRFPYYLSRHRLSHSGLRPHACPLCPKAFRRPAHLSRHLRGHGPQPPLR-----------------------------------------------CAACPRTFPEPAQLR--------RHLAQEHAGSEVDLSTQRAVKEEPEASWGPQDEGVEQPATVVVAG------------AEEEATTQWPAGDSAPAAVPTSTDPRESEAKEAEAG-------------------AAELRAELALAAGRQEEKQVLLQADWTLL----CLRCREAFATKGELKAHPCLRPEG-----------------------------------------------------------EQEGEGGPPPRPKRHQCSICLKAFARPWSLSRHRLVHSTD----RPFVCPDCGLAFRLASYLRQHRRVHG-PLSLLAPLPGAGKKDDKASGGRNSGKGPEGG--------EGAECGGASEGGEGGHNGGDATPARPPAGEPRFWCPECGKGFRRR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHLRQHGVTHSGARPFQCVRCQREFKRLADLARHAQVHAG------------GPAPHPCPRCPRRFSRAYSLLRHQRCHRAELERAELERAAA-----------------------------------------------------------------------------------------------LQELQTQASQSPQPPQPLKQEAEGLPLPIAHIKEEPPSPG----TPPQSPPAPPVFLSASCFDSQDHSAFEMEDEEMDSKAHLCGLGGLAS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .: . : . . . . : . : ... . . . : : . * ::: . * * : . . * * :: * :* : * * ** .* : * .* : .. *. . . * . : : : * .* . * : *. : : * .* * * * :. * .* : * * :* * : : . .. .: . .: .. . . . . :. :. :: ", "identical_positions": 31, "similar_positions": 79, "identity": "2.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110913-11", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JW23-1", "uniprot_id": "A0A0G2JW23_RAT", "id": "A0A0G2JW23-1", "name": "NACHT, LRR and PYD domains-containing protein 12", "aln": "------------------------MLPATAKDALHRLSTYLEELEAGELKKFKLYLG-IAEELGQDKIPRGRMEMAGPLEMAQLMVAHMGTKEAWLLALSTFERIH----------RKDLWERGQGEDLVRVTPSNGLCSLESQS-----------TCLSDVSPDAPRKDPQIT--YKDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPIWAQQKLLETGWEHSRTRGHQASPIQMETLFEPDEERPEPPRTVVLQGAAGMGKSMLTHKVMLDWADGRLFQDQFDYVFYISCRELNRSHTQC-SVHDLLSSCWPEHGAPLEDLIRAPDRLLFIIDGFHELHPSFHDVQGPWCHCWEEKRPTELLLGSLIRRLLLPQLSLLITTRPCALEKLHGLLEHPRHVEILGFSEAEREEYFYRYFHNTGQASQVFSFMRDYEPLFTMCFVPMVSWVVCTCLK-----QQLESGELLRQTSRTTTAVYMFYLLSLMQP------KPG-TPTFKVPANQRGLVSLAAEGLWNQKILFEEEDLGKHGLDGAEVSTFLNVNIFQKGIKC----EKFYSFIHLSFQEFFTAMYCALHGREA------------------VRRALAEYGFSERNFLAHTVRFLFGLLNEEMRCYLERNLGWTISP-QVKEEALAWIQNKARSEGSTLQHGSLELLSCLYEIQEEDFIQQALSHFQVVVVRNLSTKMEHVVCSFCARYCRGTEVLHLYGSAYSTGAEDGPPEPPGAQTQS------------THSQERNILPDIYSAYLSATICTNS-----------------------------------NLIELALYRNALGSQGVRLLCQGLRHANCKLQNLRLKRCHISGSACQDLAAAIIA-NRNLIRLDLSGNSIGVLGLELLCEGLQHPMCRLQMIQLRKCLLEAAAGRALASVLSNN-SHLVELDLTGNPLEDLGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMNQSLMELDLGLNDLGDSGALLLCEGLRHPDCKLQTLRLGICRLGSDACAGVAS-VLQVNTCLRELDLSFNDLGDRGLWLLGEGLRHQTCRLQKLWLDSCGLTSKACEDLSSVLGISQTLNELYLTNNALGDTGVRLLCKRLRHPGCKLRVLWLFGMDLN-KVTHRRMAALRVTKPYLDIGC---------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D4A523-1", "uniprot_id": "NLRP3_RAT", "id": "D4A523-1", "name": "NACHT, LRR and PYD domains-containing protein 3", "aln": "---------------------------MKMMSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCVPIPRGQMEKADHLDLATLMIDFNGEEKAWGMAVWIFAAIN----------RRDLWEKAKKDQPEWNDACTSNLSMVCQEDSLEEEWIGLLGYLSRISICKKKKDYCKI--YRRHVRSRFYSIKDRNARLGESVDLNRRYTQLQLVKEHPSKQEREHELLTIGRTKMWDR--PMSSLKLELLFEPEDEHLEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVS-LRAPK-SLADLIISCWPDPNPPVCKILCKPSRILFLMDGFDELQGAFDEHIEEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEILFTMCFIPLVCWIVCTGLK-----QQMETGKSLAQTSKTTTAVYVFFLSSLLQS------RGG-IEEHLFSAYLPGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDC----ERFYSFSHMTFQEFFAAMYYLLEEEEEGVTVRKGPEGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQ-QVRLELLKWIEVKAKAKKLQRQPSQLELFYCLYEMQEEDFVQSAMGHFPKIEIN-LSTRMDHVVSSFCIKNCHRVKTLSLGFLHNSPKEEE--EEKRGSQ---------------PLDQVQCVFPDPHVACSS----------------------------------------------------------------------------RLVNCCLTSSFCRGLFSSLST-NQSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLTHQCCFNISSVLSSS-QKLVELDLSDNALGDFGVRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSNHSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSLCCSALTS-VLKTNQNLTHLYLRSNALGDMGLKLLCEGLLHPDCKLQMLELDNCSLTSHSCWDLSTILTHNQSLRKLNLSNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLN-CETKRTLEALQEEKPELTVVFEISW-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "F1M918-1", "uniprot_id": "F1M918_RAT", "id": "F1M918-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------MKTE----------DEEMEDQLSKEE-------------------------------------IVSEDKEFD--YRTIIKENFFIIWDKTSLLGESATLN-------CVTTHKDQK------------------------LLEHIFDVNIQTSKSPQTVVLYGAAGIGKTTLLKKAVLEWADGNLYQ-QFTHVFYLSGREIS-QEKEK-NFAQLISKHWPSSEGPIEQILCKPSSLLFILDSFDELDFSFEEPEFALCRDWTQKHPVSFLISSLLRKVMLPESYLLVTTRTTAWKRLVPLLQKPHRVKLPGLSRSSRIDYIHHLLKDKTWAMNAVCSIRMNAKLFNMCHVCHVCQMICTFLK-----EQVEKGGNVEMTCQTSTALFTYYICSLFPR------IAGSSVTLPNETLLRSLCQAAVEGIWTMKHVLYQQNLRKHELTREDLSLFLEANVLQQDTEC----ENCYTFTHLQVQEYFAALFYLLRENPE--------EKDHPLEPFENVHLLLESNHFHDPHLEQMKCFLFGLLNKDRVQQLEETFNLTISR-AVREELLVCLEALEKDDSPLSQLRIQDLLHCIYETQDEEFITQALTYFQKIMVK-VDEESKLLIYSYCLKHCHSLQTVRLTARADLRNMLDPTAEICLEDAAVRIIHYWQDLFSVLHTNESLLEMDLYESRLDESLMKILNEEFSHPKCNLQKVMFRAVCFLNSCYDFSFLAFNNTVTHLDLKDTDLGDNGVKTLCEALKYQGCKLRVLRLESCDLNVTHCQNLSKALQS-NRSLVFLNLSTNSLSNDGVKSLCEVLENPNCPLERLALASCGLTKVGCEVLSSALTKT-KRLTHLCLAHNVLEDEGIELLSYTLRHPRCTLQSLVLRCCYFTPIGSEHLSTALQNNKSLIHLDLGFNKLADSGVKLLCQTLQQPNCNLQELELMGCVLTSEACGDLAS-VLVNNSNLWNLDLGNNILDDAGLNILCEALRNPNCQIRRLGLENCGLTPGCCQDLLDLLSNNQSVIQMNLMKNSLDYEAIRNLCKVLRSPTCKMEFLALDKKDLFKKKIKKFLVDVRINNPHLVIRPQCPNTESGCWWQYF-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q66X01-1", "uniprot_id": "NLR9C_MOUSE", "id": "Q66X01-1", "name": "NACHT, LRR and PYD domains-containing protein 9C", "aln": "----------------------------MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYP-RQVWDMVLNLFLQVN----------RKDLSTMAQIER----------------------------------------RDKQNK--YKEFMKNLFQYIWTSETNTYMPDRSYN------TIIDR----------------------------QYKALLDIFDSESDP-ATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLN-NTTEL-SLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELR-TNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQS-IYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLM-----WGHYSREEVISSSESTSAIHTIFIMSAFKS------IFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNN----IMFY---HSTLQWYFATLFYFLKQDKD----------TYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFK-TIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVD-ISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCN---------------------------------------------------SLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQ-IPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLIN--SKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISA-VLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFS-EESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32TQA8-1", "uniprot_id": "A0AB32TQA8_DANRE", "id": "A0AB32TQA8-1", "name": "", "aln": "MAEEQVKDSLSEKQSVRSGSCVSSSVSLKSDNSKGGRTPNFRGKTPSSVKRFFHLGKSKHPPSNLREKTPSSAESFQYELPDSRNKTHRSQKSFRGHLQKIFENLESKIIKFVKKELKNFRKILQNENRQEFVKEFNENSSGITEAALDLTLFFLREMKQDQAADTLQGELLYINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQS-LEIQVECKHLFEAAEQ-DEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQ-DISFIFPLPFREMNLKEKERQSLKDLITQFFPETKG-LNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSVVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCID-RLTEIRGFNDTQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVLCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNNK---KQAEKSRNKVMINLLKTAVDKALESENGHLDLYLRFLLSLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGN--LSPERSINLFYCLNELNDQTLLKQIQSHLSRGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQR------------------------------SDECLIRLSAVIKTSKR--------------------------------------------------------------------------ALLQCCNLTVQCCESISSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQQCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGEKRITAG-------PHKYVCFLTLDPNTAHTR--LILSEENREVKCVRENQPYPDHPHRFDYYLQVLCRESVCGRCYWEIDWSGD--DGVCISVSYKSIRRKRGGAECAFGRNAQSWSLICSSSSFTFRHNNSHTDLTVKP------LSRRIGVFVDHSAGTLIFYDIYRDTMS-LIHSVQTTFTEPLCPGFYVSYGSSVKLS--------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .:: . : : : :: : : : : ::: . . *.: *. * **: :* :*:** * : : .:* : .:. .. :*: . *. : :**::*.:. :. * . . :: .*:: :**. : : : .:: . : : *:. . : : . . : . :: ** :* : : .: * : : .: : :. :: : . * * : : :: . :* : . : : . * * .* :::::: * : : . *::.: : *. : : * : :: . . .*: *: * ::: :: . : : : : . . * . :. .: : * *:* . : :. *.. *: * :: : * * : ::: * . .:: .* * * : *: :*. *.. * .* * . :: : * :. * :*.: : .* : : . . : : . : :.: . . . * . : :: .: : : : : : : . : : ", "identical_positions": 62, "similar_positions": 216, "identity": "5.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110913-131", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NAF0-1", "uniprot_id": "ZN579_HUMAN", "id": "Q8NAF0-1", "name": "Zinc finger protein 579", "aln": "--MDPQPPPPAQGSPPHRGRGRGRGRGRGRGRGRGRGGAGAPRAPLPCPTCGRLFRFPYYLSRHRLSHSGLRPHACPLCPKAFRRPAHLSRHLRGHGPQPPLRCAACPRTFPEPAQLRRHLAQEHAGGEVELAIERVAKETAEPSWGPQDEGSEPPTTAAAGATEEEAVAAWPETWPAGEPSTLAAPTSAAEPRESESEEAEAGAAELRAELALAAGRQEEKQVLLQADWTLLCLRCREAFATKGELKAHPCLRPEGEQEGEGGPPPRPKRHQCSICLKAFARPWSLSRHRLVHSTDRPFVCPDCGLAFRLASYLRQHRRVHGPLSLLAPLPAAGKKDDKASGARNSAKGPEGGEGAECGGASEGGEGQNGGDAAPARPPAGEPRFWCPECGKGFRRRAHLRQHGVTHSGARPFQCVRCQREFKRLADLARHAQVHAGGPAPHPCPRCPRRFSRAYSLLRHQRCHRAELERAAALQALQAQAPTSPPPPPPPLKAEQEEEGLPLPLANIKEEPPSPGTPPQSPPAPPVFLSASCFDSQDHSAFEMEEEEVDSKAHLRGLGGLAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TMN9-1", "uniprot_id": "A0AB32TMN9_DANRE", "id": "A0AB32TMN9-1", "name": "", "aln": "MAFVKEESEDVKIEETFTVKQEDLHEQTDLFKEYERSKEEEHHVKIEDKTH--------LETDDILKMRDKRCFTCNQCGKSLANKSKLKIHMRVHNREKLFTCTQCGKNFNQSSHLNQHMRIHTG--------------------------EKPFTCTQCG-------------------------------------KSFSYSANLNQHMRIHTGEK-----------PFTCTQCGKSFSNSANLNQHMRIHTG------------EKPFTCTQCGKSFSQSSYLNQHMRIHTGEKPFTCTQCGKSFSQSPYLNQHMRIH--------------------------TGEKPFTCSQCGKSFS----QSSSLYLHMRIHTGEKPFTCTQCGKSFSKSSNLNIHMRNHTGEKPFTCLQCGKSFSQSTSLNLHMRIHTG-EKPFTCTQCGKSFSQSSNPNIHMRNHIGEKPFTCTQCEKSFSQSTSLNRQMMIHTGEKEFMCLKCENTFITAAELKRHQRVHTGEKP--YKCSQCSKRFARSGTLKTHERIHIGEKL--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . .: . .. : .. . . : *. :. : * : . *. . * .:* * *:: . ::*. *:* *. : : *: * :.* :.::*.:*: . . .:* * : .* :: : :*:*. .: : :*.: .: * :* ::*:...:*: * ::. * . *: * *:*::. *.:* :*: ::**.*.:** :* :.**.** *:* .* : ::** : . *... * :** * *.:***.* : ::*. * .*:* :** *::* :.*.: :.* * ::*:* *..*.:* : **:: . * * * .* :.: . . .** ..*:* * : *. . :: * : .:.* . :*. .*.:. :* ", "identical_positions": 93, "similar_positions": 162, "identity": "16.49%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110913-138", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0AB32TKY4-1", "uniprot_id": "A0AB32TKY4_DANRE", "id": "A0AB32TKY4-1", "name": "", "aln": "-----------------------------------------------MAFIKEES--------------------------EDVKIEETFS--------------------------------------------------------------------VKNE------------------------------------------DLQEQTDLVKEYERSKEEE------HHVKIEDK--------------------------------------THLETDDILKMRDK---------------------------------------------------------------------------------------------------------------RCFTCNQCGKSLANKSKLKIHMRIHNREKLFTCTQCGKNFNQSSNLNQHMRIHTGEKPFTCTQCGKSFSQSSNLNLHMRIHTGEKPFTCSQCGKSFSQSSSLNLHMRIHTGEKPFTCTQCGKSFSQSSILNIHMRNHTGEKPFTCLQCGKSFSQSTYLNQHMRIHTGENLFTCTQCGKSFSNSANLNLHMRIHTGEKPFTCTQCGKSFSQSSNLNIHMRIHTGEKPFTCSQCGKSFSQSPYLNHHMRIHTGEKPFTCSQCGKSFSKSSNLNIHMRIHTGEKPFTCTQCGTSFSQSSNLNIHMRNHTGEKPFTCLQCGKSFSRSTSLNRHMMIHTGEKAFMCLKCENTFITAAELKRHQRVHTGEKPYKCSQCSKRFARSGTLKTHERIHTGEKL-----------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q4V348-1", "uniprot_id": "Z658B_HUMAN", "id": "Q4V348-1", "name": "Zinc finger protein 658B", "aln": "MMNLEKNFDKTTLFNHMRTDKRGKCSDLNEYGTSCDKTTAVEYNKVHMAMTHYECNERGINFSRKSPLTQSQRTITGWSAFESNKCEENFSQSSAHIVHQKTQAGDKFGEHNECTDALYQKLDFTAHQRIHTDFTAHQKFYLSDEHGKCRKSFYWKAHLIQHERPHSGEKTYQYEECAK--------SFCSSSHPIQHPGTYVGFKLYECNECGKAFCQNSNLS------KHLRIHTKEKPCDNNGCGRSYKSPLIGHQKTDAEMELCGGSEYGKTSHLKGHQRILMGEKPYECIECGKTFSKTSHLRAHQRIHTGEKPYECVECEKTFSHKTHLSVHQRVHTGEKPYECNDCGKSFTYNSALRAHQRIHTGEKPYECSDCEKTFAHNSALRAHHRIHTGEKPYECNECGRSFAHISVLKAHQRIHTREKPYECNECGRSFTYNSALRAHQRIHTGRKPYECSDCEKTFAHNSALKIHQRIHTGEKPYKCNECEKTFAHNSALRAHQNIHTGEKLYECSECGKTFFQKTRLSTHRRIHTGEKPYECSKCGKTFSQKSYLSGHERIHTGEKPYECNVCGKTFVYKAALIVHQRIHTGEKPYECNECGKTFSQRTHLCAHQRIHTGEKPYECNECGKTFADNSALRAHHRIHTGEKPYECNDCGKTFSKTSHLRAHLRTRSGEKPYECSECGKTFSEKSYVSAHQRVHTGEKPYECNVCGKPFAHNSTLRVHQRIHTGEKSYECNDCGKTFSQKSHLSAHQRIHTGEKPYECNECGKAFAQNSTLRVHQRIHTGEKPYECDECGKTFVRKAALRVHHTRMHTREKTLACNGFGKS---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9HCG1-1", "uniprot_id": "ZN160_HUMAN", "id": "Q9HCG1-1", "name": "Zinc finger protein 160", "aln": "-MALTQVRLTFRDVAIEFSQEEWKCLDPAQRILYRDVMLENYWNLVSLGLCHFDMNIISMLEEGKEPWTVKSCVKIARKPRTPECVKGVVTDIPPKCTIKDLLPKEKSSTEAVFHTVVLERHE--SPDIEDFSFKEPQKNVHDFECQWRDDTGNYKGVLMAQK---EGKRDQRDRRDIENKLMNNQLGVSFHSHLPELQLFQGEGKMYECNQVEKSTNNGSSVSPLQQIPSSVQTHRSKKYH-ELNHFSLLTQRRKANSCGKPYKCNECGKAFTQNSNLTSHRRIHSGEKPYKCSECGKTFTVRSNLTIHQVIHTGEK----------------------------PYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFRGHSNLTTHQLIHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAFSVRSSLAIHQTIHTGEKPYKCNECGKVFRYNSYLGRHRRVHTGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNECSKVFTQNSQLANHRRIHTGEKPYKCNECGKAFSVRSSLTTHQAIHSGEKPYKCIECGKSFTQKSHLRSHRGIHSGEKPYKCNECGKVFAQTSQLARHWRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTGEKPYRCNECGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNAHLANHRRIHTGEKPYRCTECGKAFRVRSSLTTHMA-IHTGEKRYKCNECGKVFRQSSNLASHHRMHTGEKPYK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96SE7-1", "uniprot_id": "ZN347_HUMAN", "id": "Q96SE7-1", "name": "Zinc finger protein 347", "aln": "-MALTQGQVTFRDVAIEFSQEEWTCLDPAQRTLYRDVMLENYRNLASLGISCFDLSIISMLEQGKEPFTLESQVQIAGNPDGWEWIKAVITALSSEFVMKDLLHKGKSNTGEVFQTVMLERQE--SQDIEGCSFREVQKNTHGLEYQCRDAEGNYKGVLLTQEGNLTHGRDEHDKRDARNKLIKNQLGLSLQSHLPELQLFQYEGKIYECNQVEKSFNNNSSVSPPQQMPYNVKTHISKKYLKDFISSLLLTQGQKANNWGSPYKSNGCGMVFPQNSHLASHQRSHTKEKPYKCYECGKAFRTRSNLTTHQVIHTGEKRYKCNECGKVFSRNSQLSQHQKIHTGEKPYKCNECGKVFTQNSHLVRHRGIHTGEKPYKCNECGKAFRARSSLAIHQATHSGEKPYKCNECGKVFTQNSHLTNHWRIHTGEKPYKCNECGKAFGVRSSLAIHLVIHTGEKPYKCHECGKVFRRNSHLARHQLIHTGEKPYKCNECGKAFRAHSNLTTHQVIHTGEKPYKCNECGKVFTQNSHLANHQRIHTGVKPYMCNECGKAFSVYSSLTTHQVIHTGEKPYKCNECGKVFTQNSHLARHRGIHTGEKPYKCNECGKVFRHNSYLSRHQRIHTGEKPYKYNEYGKAFSEHSNLTTHQVIHTGEKPYKCNECGKVFTQNSHLARHRRVHTGGKPYQCNECGKAFSQTSKLARHQRVHTGEKPYECNQCGKAFSVRSSLTTHQAIHTGKKPYKCNECGKVFTQNSHLARHRGIHTGEKPYKCNECGKAFSQTSKLARHQRIHTGEKPY---ECGKPFSICSSLTTHQT-IHTGGKPYKCNVW-KVLKSEFKPCKPSQNS-------", "tax_id": 9606, "tax_name": "Human" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.: : : .: : :: .: * .: * .... . :: . . ::* . :* : : **:**: ::: * * * ***. ** : *.:**: * * * * ****.**: * :* * * .* * * :******:.*.:* *:* * * * **** * : *.:*.* * *.: * * * *** **: * :***:** : *. * **:**: : * *** * .: * * **:****: *.:*** * : : * * *:******: .: *::*:: . * * *******: * :*** * :.* * * * ::* **: *.:**.:** * : * ******: * *** *: : * * ***:*.: * .* :.* : * *: :***:***:*.:*.* *::.. * *.******* ", "identical_positions": 177, "similar_positions": 114, "identity": "20.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110913-161", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6NN14-1", "uniprot_id": "ZN729_HUMAN", "id": "A6NN14-1", "name": "Zinc finger protein 729", "aln": "MPGAPGSLEMGPLTFRDVTIEFSLEEWQCLDTVQQNLYRDVMLENYRNLVFLGMAVFKPDLITCLKQGKEPWNMKRHEMVTKPPVMRSHFTQDLWPDQSTKDSFQEVILRTYARCGHKNLRLRKDCKSANEGKMHKEGYNKLNQCRTATQRKIFQCNKHMKVFHKYSNRNKVRHTKKKTFKCIKCSKSFFMLSCLIRHKRIHIRQNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFSSTFTKHKRIHTGETPFRCEECGKAFNQSSNLTDHKRIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTAEKPYKCEDCGKTFNHFSALRKHKIIHTGKKPYKREECGKAFSQSSTLRKHEIIHTGEKPYKCEECGKAFKWSSKLTVHKVVHTGEKPYKCEECGKAFSQFSTLKKHKIIHTGKKPYKCEECGKAFNSSSTLMKHKIIHTGEKPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYKCEECGKAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTGKKPYKCEECGKAFSQSSSLRKHEIIHSGEKPYKCEECGKAFKWLSKLTVHKVIHTAEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKHKIIHTGKKPYKCAECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKDFNNSSTLKKHKLIHTREKLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGKAFKWSSKLTEHKVIHTGEKPCKCEECDKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCEECGKAFSQSSILTKHKIIHSVEKPYKCEECGKAFNQSSHLTRHKTIHTGEKPYKCEECGKAFIQCSYLIRHKTIHTREKPTNVKKVPKLLSNPHTLLDKTIHTGEKPYKCEECAKAF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9QDC4-1", "uniprot_id": "E9QDC4_DANRE", "id": "E9QDC4-1", "name": "", "aln": "-----------------------------------------------------MAFIK----------EESEDVKIEETFTVK---------------------------------QEDPQEQTDLIEEYEGSKQEE--------------------HHVKIEEK-------------------------------------------------------THLQTDGVLKRRDK---------------------------NRFTCTQCGRSFGRKGDLRIHMRIHTGEKISTCTQCGKSF------------------------------------------GRK--------------DHLKIHMMIHTGEKPFTCTQCGKSFSYSSHLNEHMRIHTGEKPFTCTQCGKSFSHLSSLNQHIRIHTGEKPFTCTQCGKSFRHSLILKQHIRIHTGEKPFTCTQCGKSFRQSSSLNYHKKIHTGEKPFTCTQCGKSFSQSSSFNQHMRIHTGEKPFTCTQCGKSFSQSSSFNYHMRIHTGEKPFKCTQCGKSFRISTSLNLHMMSHTREKPFTCT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **.:* :*. ::* .* .* ::: : :.* . **. ::* :*:*: .* : * .. ::: .** . * * :**::*.:..:* * ******* .* :***:* *:* . *: * :*******:.* :***:*.:**:*. * :******:.* :***:**::*:*::* ****:**:.* :***:*. * * :* *******:.* :***:***** *. ** *******:.* :***:*.: *.:.:* ****:**:.* :***:*****::. * *******:** :***:*: *:.*.:* : ** *** .* ", "identical_positions": 156, "similar_positions": 103, "identity": "12.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110913-56", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZY46-1", "uniprot_id": "A0A8I5ZY46_RAT", "id": "A0A8I5ZY46-1", "name": "", "aln": "MDSVTFEDVAVSFTQEEWTLLDPPQKKLYVSVMLETCSNLASVGIKSEYQTIEDLYKQPGKNIRNIITCSEYTPYDLEDHGKKQYPSSSLTTIHIYMRTPPVSRTDGCELCAKPVGVPRSCDTHKQIQSGEQPHEDSICETAFICPSSFCIRGGPPTEENSSECKPCGPTPGSLNYLPLPSGTHNEEKHFDCAQRVKAFGYHGSLQRHERICAGEKPHECKQCGKSFIYPYLLKMHERYHTGEKPHQCKACGKAFLCSSFLQRHKRTHTGEKPYKCKQCAKPFRRLSNLQVHERTHTGEKPYECKQCGKALRSHSSLQRHKILHAGKKPYECKLCGKSFIYPYLLQTHERSHTGEKPYTCSLCSKAFRCSSFLQRHERTHTGGKPYACKQCGKAFKGRSSLRLHARSHSGEKPHKCNICSKAFLCPSFLRRHERTHTREKPYKCRKCNKTFRGQSSLQLHERAHTGEKPYKCEICSKTFLCSSLLQRHGRIHCEERPYACKQSGQDSKDTSSFQRQKVSQAGEKPYECKQCGKSFIYPCLLQVHLRTHTGEKPYECQQCDKAFRSLSYLRIHEGSHTEEKPYECKECGKTLSCSSALQLHKRTHTGEKPYACQQCGKAFRGFSYLRVHQRTHTEDKPYECRQCGKILSCSSSLQLHERTHTGEKPYECKQCGKAFRGLSRLRVHEIIHTGEKPHECKLCGKAFKYHSLLQVHERTHIGEKPYACKQCSKAFKSLSNLRIHEKTHSGFYECKQCGKTLSSSNSLQVHERVHSGENSYECKQCGKTFRRPSNLQVHEKTHAEGKPYECKQCGKSFIYRYLLEKHEKSHSAEKPYKCAICSKAFVCPSFLQRHERIHSAARPHECVQCGKAFKGLSSLQLHERAHAREKHYDCTQCGKTFRCHSLLRAHERTHTGEKPYECAECGKTFKSAGYLRIHEKTHSGFYECKQCGKILSCSSSLQLHERTHTGEKPYECKQCGKAFRGQSSLRRHERIHAGEKPYECKQCGKSFIYPCYLQMHERSHTGEKLYKCNMCSKAFLYPCFLQMHERTHTGEKPYKCKQCEKAFRSHSSLQMHEKTHTGEKPYECKQCGKVLISHSSLQRHKIAHAGGRRCECKQCGKSFPYPYLLQIHERSHTGEKPYECKDCRKAFTCSRSLQRHGKTHT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "H0WE81-1", "uniprot_id": "H0WE81_DANRE", "id": "H0WE81-1", "name": "", "aln": "----------MAFIKEE-----------------------------SEDVKIEETFTVKQE--------------DLQEQ----------TDLIVLKEETQCNKME---------------EQHQEITADEKP---------------------TLTEKTSS--------------------------------------------------------------------------------------------------LGRPRKSKT-ECNFSSKQRRKSFIQKRNLGDHMRVHTREKPYTCEQCGKSFGKKRSLK----------------------------THMRIHTGERPYTCQQCGKSFKQIGTLKGHMRIHTGERPYTCQQCGKSFKQSATLKGHMRSHTGER----------------------------------------------------------------------------------------------------------------PYTCQQCGQSFYY--------------------------------------------------------AGNFAAHKRIHTGEKPYTCQQCGKSFK----------------------------QSGTLKGHIRTHNGGK----TLCGKSFAQKQKLDTDMMIHTGEKPYTCTECGKSFTCKSSLINHMKTHTREKLFACNQCEKSFTCKANLMNHMDGHS--------------------------GIIVFICDQCGKSLTRKDYIKQHMKTHSREDRFRCSECGKSFKQKINLSAHMKLHNAEQSPQH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* :** ** .**: :. : **::: * : : . . .: : : *::* :.*:* . **:.** * * ::::* * :..** *.* : ** * *.** **** *:****:: .: **: ** * ****:****. *.*:*: . *: * * *** :**:*:****:** ::*: * ***:**: ** *:***:** * :. : *** *******:******:*: *.:*: * ***.* * . ***:* .:* .. :*******: *. ***:*. :* * * :** ** :**:**.*:*.. :** * . ** * : *.****:: * . :: * ***:. . :.*.:***** : *. * * *.**:. : ", "identical_positions": 171, "similar_positions": 112, "identity": "14.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110913-70", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2ARR6-1", "uniprot_id": "A2ARR6_MOUSE", "id": "A2ARR6-1", "name": "", "aln": "MDLVTYDDVHVNFTQEEWALLHPSQKSLYKGVMLETYRNLTAIGYIWEEHTIEDHFQTSRSHGRHERSCSAEQPPEFIQCGKAFAYESGRQRHQIKHTGGKHHDCNQCGKDFRTRNAPQIHKRTHTGEKPYDCNQYGKAFARISHLRVHKRTHTGEKPYECNQCGKAFASSSDLQKHKRTHTGEKPYECNQCGKAFAQSSHLRIHKRTHAGDKRYECNQCGKAFTQSNNLQIHKGTHAGEKRYECNQCGKAFASSSDLQKHKRTHTGEKPYECNQCGKAFAKSCDLQKHKRTHTGEKPYECKQCGKAFAISYTLQIHNRTHTGEKPYECKQCGKAFAQSSNLRIHKQTHTGERLYECN-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2AW66-1", "uniprot_id": "A2AW66_MOUSE", "id": "A2AW66-1", "name": "", "aln": "MDLVTYDDVHVNFTQEEWALLHPSQKSLYKGVMLETYRNLTAIGYIWEEHTIEDHFQTSRSHGRHERSCSAEQPPEFIQCGKAFAYESGRQRHQIKHTGGKHHDCNQCGKDFRTRNVPQIHKRTHTGEKPYDCNQYGKAFARISHLRVHKRTHTGEKPYECNQCGKAFASSSDLQKHKRTHTGEKPYECNQCGKAFAQSSHLRIHKRTHAGDKRYECNQCGKAFTQSNNLQIHKGTHAGEKRYECNQCGKAFASSSDLQKHKRTHTGEKPYECNQCGKAFAKSCDLQKHKRTHTGEKPYECKQCGKAFAVSYTLQIHNRTHTGEKPYECKQCGKAFAQSSNLRIHKQTHTGERLYECN-----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2ARR8-1", "uniprot_id": "A2ARR8_MOUSE", "id": "A2ARR8-1", "name": "", "aln": "MNLITYDDVHVNFTQEEWALLDPSHKNLYKDVMVETYRNLTAIGYIWEEHTSEDHFQTSRSHGRHERSCSAEQPSEFIHCGKAFANESGSQRHQIKHTGEKQHDCNQCGKAFKRRSDLQIHKRTHTGEKPYECKQCGKAFSQSSHLRIHKRTHTGEKPYECKQCGKAFAQSSHLQIHKRTHTGEKPYECKQCGKAFAHSSHLHIHERTHTGEKPYECKQCGKGFARSGDLQKHKQTHTGEKPYECKQCGKAFSRKSVLQIHKRTHTGEKPYECKQCGKAFAQSSHLRIHKRAHTGLKPYECKQCGKAFAGSSGLQCHKRSHTGETPYECNQGGKPFEGSSGLEYNNRTQTAEKPYECNLCAKVLQEGVTFKEKRPYRRETL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96I27-1", "uniprot_id": "ZN625_HUMAN", "id": "Q96I27-1", "name": "Zinc finger protein 625", "aln": "---------------MGERLLESKKDHQHGEILTQVPDDMLKK----KTPRVKSCGEVSVGHASLNRHHRAD---------------TGHKPYEYQEYGQKPYKCTYCKKAFSDLPYFRTHEWAHTGGKPYDCEECGKSFISRSSIRRHRIMHSGDGPYKCNFCGKALMCLSLYLIHKRTHTGEKPYECKQCGKAFSHSGSLRIHERTHTGEKPYECSECGKAFHSSTCLHAHKITHTGEKPYECKQCGKAFVSFNSVRYHERTHTGEKPYECKQCGKAFRSASHLRTHGRTHTGEKPYECKQCGKAFGCASSVKIHERTHTGEKPCSSN---------------TSKGQGEKIA--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YYQ9-1", "uniprot_id": "A0A8M6YYQ9_DANRE", "id": "A0A8M6YYQ9-1", "name": "", "aln": "MSFIKEESEDVKIEETFTVKQEDPQEQTDLMVLKEETQHWNKMEEQHQEITADEKPTLTEKTSSLGRSRKSK--------------------------TECNFSSKQCRKSFSQKLNLDVHMRVHIREKPYTCEQCGKSFGQKKSFKTHMRIHTGERPYTCQQCGKSFCQAGNFAVHKRIHTGERPYTCQQCGKSFTQSGNLKDHIRTHNGGKKFTCTQCGKSFAQKQKYDTHMTIHTGEKPYRCTECGKSFTCKSALNNHMISHTGEKPFACVQCGKSFTTKTSLKNHMDGHTGIIVFICDQCGKSLTRKDYIKQHMKNHSREDRFRCSECGISFKQKINLSAHMKLHYAEQSPQH------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. :: : . : .. : . * :. .... * * * * .* *** *:: **:* . :: * *:*: ** *: ***:: . *** ****:** *:****:*::*. *: * *** * * : *.:***.* . . * *:*** *.*.:***:* . :. * :******: * ****:* *: * *** : *.****:: :: * :.*: * .. .*: ", "identical_positions": 88, "similar_positions": 69, "identity": "23.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110914-122", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MR9-1", "uniprot_id": "PPR3A_MOUSE", "id": "Q99MR9-1", "name": "Protein phosphatase 1 regulatory subunit 3A", "aln": "MEPAEEPGQISKDNFLEVPNLSDSVCEDEEVKATFKPGFSPQPSRRGSGSSEDMYLDTPTSASRRVSFADSLGFSLVSVKEFDCWELPSVSTDFDLSGDVFHTDEYVLSPLFDLPSSKEKLMEQLQVQKAVLESAEHLPGS-SMKGIIRVLNISFEKLVYVRMSLDDWQTHYDILAEYVPNSCDGETDQFSFKISLVPPYQKEGGKVEFCIRYETSAGTFWSNNNGTNYILVCQKKRKEPEPVKP-----------LEEAPSRQIKGCLKVKSRSKEEPLLAPEENKFE--------TLKFTESYIPTIICSHEDKDDLGANH---------------------PNVDDINKKHDEHNGKELDLMINQRLITS-----------------------QDEKNTFATDT------------------------------------------VNFTNKAEGSEKKQAYHEINTDLFMGPLSPSLSAESSLKRDFYHSRSSSPGNEYGHPHSEEIISDMGEKGPS------LGDTSSDELMQLELCSK-----------EDLDDNANPANGSGRV---CSSFDQRMACGLKNNEAG------IKKTG---IQDYKYSHGDSTKLEESN---ASSRDDYAKVDNKKEKQTCLGVNEN------------PSKNFQSVFQTQEGHMGYPKISTEGDKAN-NQDLTSLLSKDITANTWAVTVDPCPSTNAKRSWREVGS------------GSNLEPGTSDLSSPRNFSPLTDDHLFQADRENSDSSNPENQNMNTRHRKKWNVLETQSETSETESD-----------------IAKHTKEQAEYKDMWEKTDNSRNLKATPTEHLFTCRETECYGLSSLADHGITEKAQAVT--------AYIIKTTLESTPESASARGKAIIAKLPQETAGNDR--------PIEVKETAFDPHEGRKDDSHYS----------------------------------------------LCHGDTAGVIHDNDFERESHLDICNLRVDEMKK------EKTTSTCFPQKTYDKEKHGIGSVTSIDEPS--------QVITGNQKATSKLDLHLGVLPTDRAIFQANAD-------------------LELLQELSRRTDFNAVP-SAFNSDTASASRDSSQVYRHCSKKSVPS----YGEEKAVTNTTLQSIPTKSEYNWHPESEVLG-----HAMSKPE----------------------------------------------------------DVFKSSEIMKSGSGGERGGGPILQQKEGSLENSQGPMFFTNEPLENLDEASSENEGLMHSGQSQCYLGDKGLVSS-------------------------ASATVSTQELEAQGRESLLSISTN-------------------SKIPYFLLFLIFLATVYYYDLMIGLAFYLFSLYWLYWEGGRQRESVKKK---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16821-1", "uniprot_id": "PPR3A_HUMAN", "id": "Q16821-1", "name": "Protein phosphatase 1 regulatory subunit 3A", "aln": "MEPSEVPSQISKDNFLEVPNLSDSLCEDEEV--TFQPGFSPQPSRRGSDSSEDIYLDTPSSGTRRVSFADSFGFNLVSVKEFDCWELPSASTTFDLGTDIFHTEEYVLAPLFDLPSSKEDLMQQLQIQKAILESTESLLGSTSIKGIIRVLNVSFEKLVYVRMSLDDWQTHYDILAEYVPNSCDGETDQFSFKIVLVPPYQKDGSKVEFCIRYETSVGTFWSNNNGTNYTFICQKKEQEPEPVKP-----------WKEVPNRQIKGCLKVKS-SKEESSVTSEENNFE--------NPKNTDTYIPTIICSHEDKEDLEASN---------------------RNVKDVNREHDEHNEKELELMINQHLIRTRS------------------TASRDERNTFSTDP------------------------------------------VNFPNKAEGLEKKQIHGEICTDLFQRSLSPSSSAESSVKGDFYCNEKYSSGDDCTHQPSEETTSNMGEIKPS------LGDTSSDELVQLHTGSK-----------EVLDDNANPAHGNGTVQIPCPSSDQLMAGNLNKKHEGGAKNIEVKDLG---CLRRDFHSDTSACLKESTEEGSSKEDYYGNGKDDEEQRIYLGVNEK------------QRKNFQTILHDQERKMGNPKISVAGIGAS-NRDLATLLSEHTAIPTRAITADVSHSPRTNLSWEEAVLTPEHHH--LTSEGSALGGITGQVCSSRTGNVLRNDYLFQVE-EKSGGINSEDQDNSPQHKQSWNVLESQGKSRENKTN-----------------ITEHIKGQTDCEDVWGKRDNTRSLKAT-TEELFTCQETVCCELSSLADHGITEKAEAGT--------AYIIKTTSESTPESMSAREKAIIAKLPQETARSDR--------PIEVKETAFDPHEGRNDDSHYT----------------------------------------------LCQRDTVGVIYDNDFEKESRLGICNVRVDEMEK------EETMSMYNPRKTHDREKCGTGNITSVEESS--------WVITEYQKATSKLDLQLGMLPTDKTVFSENRD-------------------LRQVQELSKKTDSDAIVHSAFNSDTNRAPQNSSPFSKHHTEISVSTNEQAIAVENAVTTMASQPISTKSENICNSTREIQGIEKHPYPESKPE----------------------------------------------------------EVSRSSGIVTSGSRKERCIGQIFQTEEYSVEKSLGPMILINKPLENMEEARHENEGLVSSGQSLYTSGEKESDSS-------------------------ASTSLPVEESQAQGNESLFSKYTN-------------------SKIPYFLLFLIFLITVYHYDLMIGLTFYVLSLSWLSWEEGRQKESVKKK---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58J961-1", "uniprot_id": "A0AC58J961_DANRE", "id": "A0AC58J961-1", "name": "", "aln": "------MSVEETTCNLEPPNCKDWIMKNQED---------KMEQVAEDESEEEEPEPPLIALRRKVSFADAFGLDLVSVKEYDNRDSS-------------EGGEYYISCLFTIADLILDMEAKLQQQKLELERFELLPGSTTIRGIVRVLNLCFHKSVYVRVTLDGWQSHFELMAEYVPGSSDGQTDCFCFHLNLMPPFPVEGLRVEFCLRYESAVGTFWASNGGTNYIMFCYQRRRSNFKEHPRENEKEIEKEKVEEGLHKGIRSCLKANSKNYTEATAAEASGGIPGEFLMWRSGCKESDDKILSLIVYFTEQATAKVGRNRNKTEEEAGITSCKSLKDCCKTLVDRRRKRQAARLAHVQSYFAQKATETQMGCNSITDESSTSIPRLSIQSRTDNQQGFGMDTPPILMYHQIPLLSLDWGSTSTTPPQVNPPNTESQQVEDHQAELSFDAFLKGSDTAIPHSDMQDQACASPESLDHSEVSASRDRVGGLEDREAWKNYSQESAKRRTTNIIQSDATQQGKDPITSLSSDQVVNYQLVKEPMVTTLPWSVLDSRDQIVVPMEDRGAEKDYSQGTDDRGAIETIKSDPTVQVKDLSTSLSSDQVVDYQLAKEPSITTVPCSVLPSRDQIVVPMEDREAEKGYIQGSADRRAIETIKSDPTEQGKNLSTGLSSDQVVEDYQLAKEPSVTAIPCSVLASRDKNMIPIEDRGAKKDNSQWSDDKRAIESIKSDPTDQRKDLSLSLSSYEVVDHQLVKEPSVTIVPCSVLASREQIEVPMEDREAEKKCSQWSADRGAIEIITSDPTEQGKQPSTSLSSDQVVEDYQLVKEPSVTAIPCSFLASRDKNVVPIEDGGAEKGYILGSGDRRAIEIIKSDPTEQGKDLITRLSNDQIMNYHLGEEPSATTVPCSVLASGDQIEVPMVNKGDEKKYSQWSADRRAIETIKSDPTEQGKDRSTILSSDQVVVDCQLVKEPSVTAIPCSFLALRNKNVPIEDSGAENGYIQGSGDRRAIEIIKSDPTEKGKNLSTSLTRDQDVDYRLVKESKATTVPCFALASRDQIEVPVEELEAVKNDSQWSADRMAIEVIKSEPTEQGKDLSTGLSSDRVVDYQLVKEPRVTTVPCSVLGSEPDRLERELEASRDCQTPHHELTSGFLSQDTTKASPGDETGIAHDTETQNSEAGDGISPEECTGSSDTSKVKENTHRAVKDILTFTGIRDVPLTNRQAEGSSPKRKVINIDDSEEQVEMRWFYTELHEEDAESSRKGQDETTMDHSAEIQSVSSCASEAFNENELCTMNKNLHKDNSELQKSEERRFEANEGLKIKEQLNETTIEAAKGGEEDEMCSESKRELIEDSRAIGDNCTDEDLTSKVTYLTDSTDLPKHIPQTTSIKDREVNSQDEEFELGKSLNGSSNRLFSWWQEFNSLGHMAKALLYAILFVIFITTYLCDMPTCLALYLFSLCWWCSQGMKQRLDGASVDVD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P28006-1", "uniprot_id": "GAC1_YEAST", "id": "P28006-1", "name": "Serine/threonine-protein phosphatase 1 regulatory subunit GAC1", "aln": "--------------------------------------------------------------------------------------------------------MVIQTATTLSPAKARPSFPHNDLIKSMSDSLISRPTHPPIRKLKSSLKISHPEPISR-------------SKSEIFCTSPEKNVRFAIELTTVKRFDKNAEPSSISNENSPTLSPVDSNTAADDVQLFNNEDCWFND---------------------------------SSLVTNLLKNEKKFR---------YMNSLNNMFKLDLYDSEDE----------------------------------DDIDEHINSQAEYGYTYNSLSTRG---------------------KTSENKSATSS-------------------------------------------LATQATNICDWKLHCTDLVPFKIAPPLFTKTLSASDLQGQLTKYLNGQNVKLHSLTQLGDDSSKITG-------LVYVKNLSFEKYLEIKFTFN-----------SWRDIHYVTANFNRTINSNVDEFKFTIDLNS---------------------LKYILLIKRIITMEKNTSSCPLNIELCCRYDVNNETYYDNNNGKN-------------YHLFMTTFKKGGETKEKIPVVVEPASQTDAAMSPKEMKARFVSSNPTLSRFLPQSRKFSEDTDYYNTSP---------LKHLYHNDTTSWVKPKRLNVVLDKLENATPPPPSSALANDTARTGKITKDKNNVLAPPTASNS---------------------IDLPILGSQHQSLYSGSSSYSSSSSSISSSLSFASSNNSSTNSSSASCSFPLTELDNFD---------YANLYEPNDTFTTANLFNHSLNSLMPEIST------------PSFFGGFRNENTINNNDSKNLVTS------------------------------------------LEDSYEDKQSVITDTTMDENNKTSTINNSTDTLIK--------------PSKENGTVKENKSSANSTSAPS----------SSQNRASTILNDHSNGKSDLKYVNYQSLLDS------------------------------------HCFYNHPSSPNLQSTSFSSAAPFSGISQASDIFDYENEDSD------------------------------------------------------------------------------------------------SNQIAGEIDNNSFPPHFYLDEDDKSACLSDDALIDHHRNTNPFINTFSSSPPILSQEVDRWRL--------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q06216-1", "uniprot_id": "PIG1_YEAST", "id": "Q06216-1", "name": "Serine/threonine-protein phosphatase 1 regulatory subunit PIG1", "aln": "----------------------------------------------------------------------------------------------------------------MPYSHGKKLKPSLKLAKTISTSSFVSSTTSNSFSPLEDSTS---------------------ASSSTSSSSSGKSVRFAAHLYTVKKFNTKLAPISISEKAASNLTRNLHNNAIPLTFPFIGGE----------------------------------------------------------------DHRYSLDILDYSDLEYD-----------------------------------NKDVEYDNESDVEDNAMLMHDRS--------------------MFIEKEILCFGE---------------------------------------------EETFDMADWKLVSNNLNPFKSDYKVDVTGLEDKIFKYLNGQNIKVHSLELSDPVSYEDICSNNFGNCQIWG-LIFVNNLNFEKKIEIKFTLN-----------NWADIHYINAHYNKSVTPHVDEFKFIIDISALK-------------------LNLISKNLIYTNFFERKTTCLLNLQFCCRYDVNGFEYRSFYDNND-------------YKNYEITISLSAINLNRAVSNSSIFNSNLGPSKMGASNAEVTMSKNNENSKKP-LRKFIKDTDYYNDSP-------------------------------LKHKFYQSFETKAACKTEPVSQTFKAETIDCEIEP-------------------------------------FNYFFEPPDSQTNEDMSDSSYDLSLQDFNYWEFSNHGLGKALADSDILQ----------FKNYPKPEPFSRPPIIDDTFTLNTDDRTLGSKT---------QKLEDNLAKEWKSAKTRTTLN----------------------------------------------------ETPLHDDEHRTSFTYTTWNNSTDTLMK---------------RKEERPVESASCSQLSIATIK----------------------------AEEDLLYQDYINS------------------------------------GRESSSPEISPLNTTTSLPFFPGDNMSDSSGEYEERTSLSP-------------------------------------------------------------------------------------------------NKIHIFRDYFYKSPSP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . . :. :. *. .: : : . .:. . . .. . : : : . : . : ..: . . : :: . : . . :. : . . :: :: . : . * . . . . . . . : : . . . : : . . . :. . . : . . . . : . : . : : : . : . :. : . . . . . . . : . ", "identical_positions": 3, "similar_positions": 100, "identity": "0.2%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110914-157", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H9Z2-1", "uniprot_id": "LN28A_HUMAN", "id": "Q9H9Z2-1", "name": "Protein lin-28 homolog A", "aln": "MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGSERRPKGKSMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSISHMVASCPLKAQQGPS-AQGKPTYFREEEEEIHSPTLLPEAQN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K3Y3-1", "uniprot_id": "LN28A_MOUSE", "id": "Q8K3Y3-1", "name": "Protein lin-28 homolog A", "aln": "MGSVSNQQFAGGCAKAAEKAPEEAPPDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGSERRPKGKNMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSINHMVASCPLKAQQGPS-SQGKPAYFREEEEEIHSPALLPEAQN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IRA3-1", "uniprot_id": "A0A0R4IRA3_DANRE", "id": "A0A0R4IRA3-1", "name": "Protein lin-28 homolog A", "aln": "-------MAEGGCAKTEEEE-------GQAAEEDPRPYHGVGVCKWFNVRMGFGFLSMNTRDGVPLETPVDVFVHQSKLHMEGFRSLKEGESVEFTFKKSSKGLESVRVTGPGGAHCVGSDRRPKGKSVQKRRAKGDRCYNCGGLDHHAKECKLPPQPKRCHFCQSVAHMVANCPVKAQQSTQGSQGKSAGQKQEEADQNHS---PPATD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****: *: . * ::*: **.*:***************.:* **.*:.***********************:********:*****:*******..*:**:******.:****:*************************:******: ****.**:****... :***.: ::** : : . * * :", "identical_positions": 134, "similar_positions": 39, "identity": "63.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110914-16", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D6Y9-1", "uniprot_id": "GLGB_MOUSE", "id": "Q9D6Y9-1", "name": "1,4-alpha-glucan-branching enzyme", "aln": "MAAPAAPAAGETGPDARLEAALADVPELARLLEIDPYLKPFAADFQRRYKKFSQVLHDIGENE-----GGIDKFSR-GYESFGIHRCSD-GGIYCKEWAPGAEGVFLTGEFSGWNPFSHPYK-KLEYGKWELYIPPKQNKSPLIPHGSKLKVVITSKSGEILYRISPWAKYVVR------ENNNVNYDWIHWAPE--DPYKFKHSRPKKPR---SLRIYESHVGISSHEGKIASYKHFTSNVLPRIKDLGYNCIQLMAIMEHAYYASFGYQITSFFAASSRYGTPEELKELVDTAHSMGIVVLLDVVHSHASKNSEDGLNMFDGTDSCYFHSGP--RGTHDLWDSRLFIYSSWEVLRFLLSNIRWWLEEYCFDGFRFDGVTSMLYHHHGMGQG--FSGDYNEYFGLQ---VDEDALIYLMLANHLAHTLYP-DSITIAEDVSGMPALCSPTSQGGGGFDYRLAMAIPDKWIQLLKEFKDEDWNMGNIVYTLTNRRYLEKCVAYAESHDQALVGDKTLAFWLMDAEMYTNMSVLAPFTPVIDRGIQLHKMIRLITHGLGGEGYLNFMGNEFGHPEWLDFPRKGNNESYHYARRQFNLTDDDLLRYKFLNNFDRDMNRLEERCGWLSAPQAYVSEKHEANKTITFERAGLLFIFNFHPSKSYTDYRVGTATPGKFKIVLDSDAAEYGGHQRLDHNTNYFAEAFEHNGRPYSLLVYIPSRVALILQNVDLQN--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0LHH2-1", "uniprot_id": "A0ABK0LHH2_RAT", "id": "A0ABK0LHH2-1", "name": "1,4-alpha-glucan-branching enzyme", "aln": "MAAPAAPAAEEKGSEAQLKAALADVPELGRLLEIDPYLKPYAADFQRRYKKFNQVLHDIGENE-----GGIDKFSR-GYESFGIHRCSD-GGIYCKEWAPGAEGVFLTGEFSGWNPFSHPYK-KLEYGKWELYIPPKQNKSPPIPHGSKLKVVITSKSGEILYRISPWAKYVVR------ENNNVNYDWIHWDPE--NPYKFRHSRPKKPR---SLRIYESHVGISSHEGKIASYKHFTSNVLPRIKDLGYNCIQLMAIMEHAYYASFGYQVTSFFAASSRYGTPEELKELVDTAHLMGIVVLLDVVHSHASKNSEDGLNMFDGTDSCYFHSGP--RGTHDLWDSRLFIYSSWEVLRFLLSNIRWWLEEYCFDGFRFDGVTSMLYHHHGMGQG--FSGDYSEYFGLQ---VDEDALVYLMLANHLTHTMYP-DSITIAEDVSGMPALCSPTSQGGGGFDYRLAMAIPDKWIQLLKEFKDEDWNMGNIVYTLTNRRHLEKCVAYAESHDQALVGDKTLAFWLMDAEMYTNMSVLAPFTPVIDRGIQLHKMIRLITHGLGGEGYLNFMGNEFGHPEWLDFPRKGNNESYHYARRQFNLTDDDLLRYKFLNNFDRDMNRLEETCGWLSAPQAYVSEKHEGNKTITFERAGLLFIFNFHPSKSYTDYRVGTAMPGKFKIVLDSDAAEYGGHQRLDHSTDYFAEAFEHNGRPYSLLVYIPSRVALILQNVDLPN--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q04446-1", "uniprot_id": "GLGB_HUMAN", "id": "Q04446-1", "name": "1,4-alpha-glucan-branching enzyme", "aln": "MAAPMTPAARPEDYEAALNAALADVPELARLLEIDPYLKPYAVDFQRRYKQFSQILKNIGENE-----GGIDKFSR-GYESFGVHRCAD-GGLYCKEWAPGAEGVFLTGDFNGWNPFSYPYK-KLDYGKWELYIPPKQNKSVLVPHGSKLKVVITSKSGEILYRISPWAKYVVR------EGDNVNYDWIHWDPE--HSYEFKHSRPKKPR---SLRIYESHVGISSHEGKVASYKHFTCNVLPRIKGLGYNCIQLMAIMEHAYYASFGYQITSFFAASSRYGTPEELQELVDTAHSMGIIVLLDVVHSHASKNSADGLNMFDGTDSCYFHSGP--RGTHDLWDSRLFAYSSWEILRFLLSNIRWWLEEYRFDGFRFDGVTSMLYHHHGVGQG--FSGDYSEYFGLQ---VDEDALTYLMLANHLVHTLCP-DSITIAEDVSGMPALCSPISQGGGGFDYRLAMAIPDKWIQLLKEFKDEDWNMGDIVYTLTNRRYLEKCIAYAESHDQALVGDKSLAFWLMDAEMYTNMSVLTPFTPVIDRGIQLHKMIRLITHGLGGEGYLNFMGNEFGHPEWLDFPRKGNNESYHYARRQFHLTDDDLLRYKFLNNFDRDMNRLEERYGWLAAPQAYVSEKHEGNKIIAFERAGLLFIFNFHPSKSYTDYRVGTALPGKFKIVLDSDAAEYGGHQRLDHSTDFFSEAFEHNGRPYSLLVYIPSRVALILQNVDLPN--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T5K7-1", "uniprot_id": "A0AB32T5K7_DANRE", "id": "A0AB32T5K7-1", "name": "1,4-alpha-glucan branching enzyme", "aln": "MAESESNIS---------------VPHLKSLLQMDPYLKPFEKDFERRYGLFEKQLAFLEEAE-----GGFDHFTR-SYESFGVQRLQD-NSLVFKEWAPAAEALFLTGDFNGWDKFSHPYA-KKEFGKWELHIPPKEDKTPAVTHNSKLKVVVHTSAGERLYRISPWAKYVTR------HEKSVIYDWVHWDPP--QPYIHKHPRPQKPR---SLRIYESHVGIASPEGKIASYSNFTHNVLPRIKDLGYNSIQLMAIMEHAYYASFGYQVTSFFAASSRYGTPEELKELIDVAHSLGIIVLLDVVHSHASKNTEDGLNLFDGSDSCFFHSGP--RGEHSLWDSRLFNYSSWEVLRFLLSNLRWWMEEYKFDGFRFDGVTSMLYHHHGIGSG--FSGDYNEYFGLQ---VDEDSLVYLMLANHILHTLYE-DCITIAEDVSGMPTLCCPVQQGGLGFDYRLAMAIPDKWIQILKEFKDEDWNMGNIVFTMTNRRYGEKCIAYAESHDQALVGDKTLAFWLMDKEMYTSMSALIPMNSIIDRGIQLHKMIRLLTHSLGGEGYLNFMGNEFGHPEWLDFPRIGNNESYHYARRQYNLVDMDHLRYRQLYAFDRDMNRTEDNYGWLAAPPAYVSVKHEGDKVIVFERANLIFIFNFHPFNSYSDYRVAVGPAGKYKIKLDSDEIQYGGHGRLDHNTEFFTEAMGLNNRPNSMMVYIPCRTAIVLANEEIDYCY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z992-1", "uniprot_id": "A1Z992_DROME", "id": "A1Z992-1", "name": "1,4-alpha-glucan branching enzyme", "aln": "MAEAK---------------------DIEKLFETDGYLRPFEHEIRRRHGVLEDWLNKINQSE-----GGLDGFST-AYKHYGLHFQPD-NSVIAREWAPGARDVYLTGDFNNWHWESHPFK-KLDFGKWELHLPPNEDGSPAIKHLSEIKIIIRNHSGQLLDRLSPWAKYVVQPPK--SANQGVNYKQYVWEPPSYERYQRQHPGPPRPK---SLRIYECHVGIASQEPRVGSYDEFADRIVPRIKRQGYNCIQVMAIMEHAYYASFGYQVTSFYAASSRYGNPEQLKRMIDVAHSHGLFVLLDVVHSHASKNVQDGLNQFDGTNSCFFHDGA--RGEHSLWDSRLFNYVEYEVLRFLLSNLRWWHDEYNFDGYRFDGVTSMLYHSRGIGEG--FSGDYNEYFGLN---VDTDALNYLGLANHLLHTIDS-RIITIAEDVSGMPTLCRPVSEGGIGFDYRLGMAIPDKWIELLKEQSDDEWDMGNLVHTLTNRRWMENTVAYAESHDQALVGDKTIAFWLMDKEMYTHMSTLSDSSVIIDRGLALHKMIRLITHALGGEAYLNFMGNEFGHPEWLDFPRVGNNDSYHYARRQWNLVDDDLLKYKYLNEFDRAMNEAEERYGWLHSGPAWVSWKHEGDKIIAFERAGLVFVFNFHPQQSFTGYRVGTNWAGTYQAVLSSDDPLFGGHNRIDANCKHPSNPEGYAGRSNFIEVYTPSRTAVVYARVSD----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32775-1", "uniprot_id": "GLGB_YEAST", "id": "P32775-1", "name": "1,4-alpha-glucan-branching enzyme", "aln": "MYNIP--------------------DNVKGAVEFDPWLKPFADVLSERRYLADKWLYDITHATPDGSYQSLSKFARDSYKSYGLHANPETKEITYKEWAPNAERAFLVGDFNNWDTTSHELKNKDEFGNFTITLHPLPNGDFAIPHDSKIKVMFILPDGSKIFRLPAWITRATQPSKETSKQFGPAYEGRFWNPE--NPYKFVHPRPKFSESVDSLRIYEAHVGISSPEPKITTYKEFTEKVLPRIKYLGYDAIQLMAIMEHAYYASFGYQVTNFFAASSRFGTPEELKELIDTAHSMGILVLLDVVHSHASKNVEDGLNMFDGSDHQYFHSISSGRGEHPLWDSRLFNYGKFEVQRFLLANLAFYVDVYQFDGFRFDGVTSMLYVHHGVGAGGSFSGDYNEYLSRDRSFVDHEALAYLMLANDLVHEMLPNLAVTVAEDVSGYPTLCLPRSIGGTGFDYRLAMALPDMWIKLIKEKKDDEWEMGSIVYTLTNRRYGEKVVAYCESHDQALVGDKTLAFWLMDAAMYTDMTVLKEPSIVIDRGIALHKMIRLITHSLGGEAYLNFEGNEFGHPEWLDFPNVNNGDSYKYARRQFNLADDPLLRYQNLNEFDRSMQLCEKRHKWLNTKQAYVSLKHEGDKMIVFERNNLLFIFNFHPTNSYSDYRVGVEKAGTYHIVLNSDRAEFGGHNRINESSEFFTTDLEWNNRKNFLQVYIPSRVALVLALKE-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .: .: * :*:*: : .* .. * : . .:. *: .*: :*:: : : :**** *. :*.*:*..*. *: * ::*:: : : * : : * *::*::. *. : *:..* . ..: . *. * * . * *. * .. ******.****:* * :: :*..*: .::**** **:.**:***************:*.*:*****:*.**:*:.::*.** *:.************* **** ***:: :**. . ** * ******* * .:*: ****:*: :: : * ***:********** :*:* * *****.**:. : ** ::* ** ***.: * : :*:****** *:** * . ** ******.**:** **:::** .*::*:**.:*.*:**** *: :**.***********::****** *** *:.* . :****: *******:**.****.**** *************. .*.:**:*****::*.* *:*: * *** *: *. ** : *:** ***.:* *.*** .*:*:***** :*::.***.. .*.:: *.** :*** *:: . .. : .* : ** *.*.*:: . ", "identical_positions": 310, "similar_positions": 188, "identity": "42.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110914-188", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P21571-1", "uniprot_id": "ATP5J_RAT", "id": "P21571-1", "name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFN-KELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYG---KGEMDKFPTFNFEDPKFEVLDKPQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97450-1", "uniprot_id": "ATP5J_MOUSE", "id": "P97450-1", "name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVLQRIFRLSSVLRSAVSVHLKRNIGVTAVAFN-KELDPVQKLFVDKIREYKSKRQASGGPVDIGPEYQQDLDRELYKLKQMYG---KGEMDTFPTFKFDDPKFEVIDKPQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P18859-1", "uniprot_id": "ATP5J_HUMAN", "id": "P18859-1", "name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MILQRLFRFSSVIRSAVSVHLRRNIGVTAVAFN-KELDPIQKLFVDKIREYKSKRQTSGGPVDASSEYQQELERELFKLKQMFG---NADMNTFPTFKFEDPKFEVIEKPQA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q24407-1", "uniprot_id": "ATP5J_DROME", "id": "Q24407-1", "name": "ATP synthase-coupling factor 6, mitochondrial", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLSQSLLSGMRVLRTEA----RRNFGIVAPALN-KASDPIQQLFLDKVREYKQKS-AGGKLVDSNPDIERELKTELDRVAKQFGSDGKTDMLKFPEFQFPDVKVDPITQAPQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1RES1-1", "uniprot_id": "A0A8M1RES1_DANRE", "id": "A0A8M1RES1-1", "name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "aln": "MLIANAKVQTSTINPPVKDSSESAIPVHTKPVQDTLVDLQAVTSPTGSSLNETASRLNSILIRPAVDFAYSNVIDQNATEGLNKKKYTQISNANDLASNFVDSYAGSTTNDAHGDVTTNITQVSSQTSEVISSYEVDTQNHDAFDEHTPQVVACEETVNMADAIMTTPEVSSVFQGEELRCLSEDVNVNVNIAQAQNYPQPLPQHFPNWSSNVIADKQSSDGQILNQAFPESLPDGSAIQDISEAFCSRSGEVCQVSPSTEYIAGVSLFKSTDDLSVAGTVSACKAVKVDGLSEMSANVQSSISLKDPVLAQTDILVEENQTEAAEMLPEEQLDPIQRLFLHKIREYSTKSQASAGPVDAGADYEKAFSEELSKLQRLYG---GGDLTNFPGFKFSEPVLDESDSK--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : : . ..* .* : : **:*:**:.*:***. * :.. ** ..: :: .. ** :: : :* :: .** *:* : .: . ", "identical_positions": 22, "similar_positions": 37, "identity": "5.39%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110914-193", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D7H4-1", "uniprot_id": "AVPI1_MOUSE", "id": "Q9D7H4-1", "name": "Arginine vasopressin-induced protein 1", "aln": "MGTPASVVSEP--PLWQVSTPQTRGRKQASANIFQDAELVQIQGLFQRSGDQLAEERAQIIW---ECAG-------------------DHRVAEALRRLRRKRPPKQ-------NHCSR---------LRVPE-------PGSTASDPQASTTDTASSEQSGNSRRTSARAPR-----------------NWNKP---GPTGYLHQIRH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T686-1", "uniprot_id": "AVPI1_HUMAN", "id": "Q5T686-1", "name": "Arginine vasopressin-induced protein 1", "aln": "MGTPASVVSEP--PPWQAP-IEARGRKQASANIFQDAELLQIQALFQRSGDQLAEERAQIIW---ECAG-------------------DHRVAEALKRLRRKRPPRQKPLGHSLHHCSR---------LRILE-------PHSALANPQ-SATETASSEQYLHSRKKSARIRR-----------------NWRKS---GPTSYLHQIRH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "H0WED3-1", "uniprot_id": "H0WED3_DANRE", "id": "H0WED3-1", "name": "Arginine vasopressin-induced protein 1", "aln": "MEDVAPVLAGPSQPTFSRP-SERRNRKSGTANIFQGVNLRQLRRLFQVAGDPDAEQRARMVWGRRRAAGGAEDGADAEQDEDSGAAEVETGLAQALVGLRVRARNRSGLRVEQHKDTSGQRWVRAFGHLRINEGSLNPTTEGTPAEDEEVNEEEEESSAAGGQSSFESSSHDQGDFPSTEEETQGPGPRWSWNAVQEKDPERYLHRIRH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *.*:: * * :. . : *.**..:*****..:* *:: *** :** **:**:::* ..** : :*:** ** : :. :. * **: * :. : : . : ** :* *: : .*. .* ***:***", "identical_positions": 48, "similar_positions": 45, "identity": "22.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110914-194", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A506-1", "uniprot_id": "A0A8I6A506_RAT", "id": "A0A8I6A506-1", "name": "", "aln": "MAAP--VTRQVSGCAGRVPSPTGSDTERGQPLAAAVAELPVLDASGRRVTFGALFRERRAVVVFVRHFLCYVCKEYVEDLAKIPKSVLQEADVTLIVIGQSSYHHIEPFCKLTGYSHEIYVDPEREIYKRLGMKRGEE-ISSSG--------------------------------------------NNIHFVHRDRNRLDHKPINSVLQLVGVQPVNFLSRPAVIHV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D1A0-1", "uniprot_id": "PXL2C_MOUSE", "id": "Q9D1A0-1", "name": "Peroxiredoxin-like 2C", "aln": "MAAP--VTRQVSGCAGRVPSPAGSVTERGQPLAAAVAELPVLDASGRRVTFGALFRERRAVVVFVRHFLCYVCKEYVEDLAKIPKSVLREADVTLIVIGQSSYHHIEPFCKLTGYSHEIYVDPEREIYKRLGMKRGEE-ISSSGQSPHIKSNLLSGSLQSLWRAVTGPLFDFQGDPAQQGGTLILGPGNNIHFVHRDRNRLDHKPINSVLQLVGVQPVNFMSRPTVIHV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7RTV5-1", "uniprot_id": "PXL2C_HUMAN", "id": "Q7RTV5-1", "name": "Peroxiredoxin-like 2C", "aln": "MAAPAPVTRQVSGAAALVPAPSGPDS--GQPLAAAVAELPVLDARGQRVPFGALFRERRAVVVFVRHFLCYICKEYVEDLAKIPRSFLQEANVTLIVIGQSSYHHIEPFCKLTGYSHEIYVDPEREIYKRLGMKRGEE-IASSGQSPHIKSNLLSGSLQSLWRAVTGPLFDFQGDPAQQGGTLILGPGNNIHFIHRDRNRLDHKPINSVLQLVGVQHVNFTNRPSVIHV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AUW1-1", "uniprot_id": "A0A8M3AUW1_DANRE", "id": "A0A8M3AUW1-1", "name": "", "aln": "MAAVHPITRQISSSVQDNKQAS------HNICLSELKNCFIFDRHGDKKSFSSLFEHNKAIVIFVRHFLCYTCKEYVEDLGKIPQHVLQDSNVRLVVIGQSSYSHIQGFCSLTGFPHEIYVDPERQIYKRLGLRRGETYMETPSVSPHVKSSMLSGSLKSVWRAMTSPVFDFQGDPQQQGGALIVGPGPDVHFAHFDMNRLDHMPINWLLQLAGLPALDFSDSPKIINI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** :***:*... .: : : : : ::* * : .*.:**...:*:*:******** ********.***: .*::::* *:******* **: **.***:.*********:******::*** : :.. ::** * * ***** *** :***.*: ::* . * :*::", "identical_positions": 87, "similar_positions": 53, "identity": "37.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110914-210", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q76EQ0-1", "uniprot_id": "SRR_RAT", "id": "Q76EQ0-1", "name": "Serine racemase", "aln": "--MCAQYCISFADVEKAHLNIQDS---VHLTPVLTS--SILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTLEGKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYSEPSDESRENVAQRIIQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMVAGIAITIKTL-KPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSS-IGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWERMKLLIEPTAGVGLAAVLSQHFQTVSPEVKNICIVLSGGNVDLTS-LSWVKQAERPAP------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QZX7-1", "uniprot_id": "SRR_MOUSE", "id": "Q9QZX7-1", "name": "Serine racemase", "aln": "--MCAQYCISFADVEKAHINIQDS---IHLTPVLTS--SILNQIAGRNLFFKCELFQKTGSFKIRGALNAIRGLIPDTPEEKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPNCKKLAIQAYGASIVYCDPSDESREKVTQRIMQETEGILVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMVAGIAITIKAL-KPSVKVYAAEPSNADDCYQSKLKGELTPNLHPPETIADGVKSS-IGLNTWPIIRDLVDDVFTVTEDEIKYATQLVWGRMKLLIEPTAGVALAAVLSQHFQTVSPEVKNVCIVLSGGNVDLTS-LNWVGQAERPAPYQTVSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9GZT4-1", "uniprot_id": "SRR_HUMAN", "id": "Q9GZT4-1", "name": "Serine racemase", "aln": "--MCAQYCISFADVEKAHINIRDS---IHLTPVLTS--SILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPKAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIVYCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPLVDALVVPVGGGGMLAGIAITVKAL-KPSVKVYAAEPSNADDCYQSKLKGKLMPNLYPPETIADGVKSS-IGLNTWPIIRDLVDDIFTVTEDEIKCATQLVWERMKLLIEPTAGVGVAAVLSQHFQTVSPEVKNICIVLSGGNVDLTSSITWVKQAERPASYQSVSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P36007-1", "uniprot_id": "LTHAD_YEAST", "id": "P36007-1", "name": "L-threo-3-hydroxyaspartate ammonia-lyase", "aln": "-----MIVPTYGDVLDASNRIKEY---VNKTPVLTS--RMLNDRLGAQIYFKGENFQRVGAFKFRGAMNAVSKLSD---EKRSKGVIAFSSGNHAQAIALSAKLLNVPATIVMPEDAPALKVAATAGYGAHIIRYNRYTEDREQIGRQLAAEHGFALIPPYDHPDVIAGQGTSAKELLEEVGQLDALFVPLGGGGLLSGSALAARSL-SPGCKIFGVEPEAGNDGQQSFRSGSIVH-INTPKTIADGAQTQHLGEYTFAIIRENVDDILTVSDQELVKCMHFLAERMKVVVEPTACLGFAGALLKKEELVG---KKVGIILSGGNVDMKRYATLISGKEDGPTI-----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "A0ACD6B6W2-1", "uniprot_id": "A0ACD6B6W2_DANRE", "id": "A0ACD6B6W2-1", "name": "L-serine ammonia-lyase", "aln": "MGDVSADMITVEMLREACETVRCSPMDVIKTPMIPWSQTTLPLHTSCNIHIKLENMQRTGSFKIRGVANQFA------KRHKGDHFVTMSAGNYGKAFSYACKHYGSKGKVVMPETAPISRSVLIQNLGVEVERVP--TTQLMGVVNRCVQEDGMTFLHSIDDPDLIAGHSSLGFEILDVLPYPDVVVVCCGGGGLLSGVAAAIKLSGCEDTKIYGVEPEGACTMYKSFIEKRPVG--MDAKSIASGLAPPFAGTLAYQLCQRYVEKIVLVSDEEIKSAVSTLYK-AGLVVEPSGTAAFTAIINDKIPDIQD--KNVVVILSGGNIGKDELNNFPD-------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .* :: : **::. * . ::.:* * :*:.*:**:**. * . . : . .:: *:**:.:*:: :.* . . :*:*: ** : *. : . : .: * :: . :.* :***:.: . *:*: : *.:.* ****:::* * : : . *::..**. . :* . .::**.* . * :: : : *:.:. *:::*: . : :::**:. ..:. : .: : *:: ::*****:. . ", "identical_positions": 57, "similar_positions": 116, "identity": "16.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110914-219", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96GR2-1", "uniprot_id": "ACBG1_HUMAN", "id": "Q96GR2-1", "name": "Long-chain-fatty-acid--CoA ligase ACSBG1", "aln": "MPRNSGAGYGCPHGDPSMLDSRETPQESRQDMIVRTTQEKLKTSSLTDRQPLSKESLNHALELSVPEKVNNAQWDAPEEALWTTRADGRVRLRIDPSCPQLPYTVHRMFYEALDKYGDLIALGFKRQDKWEHISYSQYYLLARRAAKGFLKLGLKQAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAYDCCANVIMVDTQKQLEKILKIWKQLPHLKAVVIYKEPPPNKMANVYTMEEFMELGNEVPEEALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNITWTARYGSQAGDIRPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFAEPDALKGSLVNTLREVEPTSHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSVTLEQNLTCPGSDLKPFTTRLADYLVLAKVRQALGFAKCQKNFYGAAPMMAETQHFFLGLNIRLYAGYGLSETSGPHFMSSPYNYRLYSSGKLVPGCRVKLVNQDAEGIGEICLWGRTIFMGYLNMEDKTCEAIDEEGWLHTGDAGRLDADGFLYITGRLKELIITAGGENVPPVPIEEAVKMELPIISNAMLIGDQRKFLSMLLTLKCTLDPDTSDQTDNLTEQAMEFCQRVGSRATTVSEIIEKKDEAVYQAIEEGIRRVNMNAAARPYHIQKWAILERDFSISGGELGPTMKLKRLTVLEKYKGIIDSFYQEQKM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99PU5-1", "uniprot_id": "ACBG1_MOUSE", "id": "Q99PU5-1", "name": "Long-chain-fatty-acid--CoA ligase ACSBG1", "aln": "MPRGSEAGYCCLSRDSNMPDSRDDQQ---QGASLGTSQDNSQTSSLIDGQTLSKESPSHGLELSAPEKARAASLDGAEEALWTTRADGRVRLRLEPFCTQRPYTVHQMFYEALDKYGNLSALGFKRKDKWERISYYQYYLIARKVAKGFLKLGLERAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYISHDCRANVIVVDTQKQLEKILKIWKDLPHLKAVVIYQEPPPKKMANVYTMEELIELGQEVPEEALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQDNITWTARYGSQAGDIQPAEVQQEVVVSYLPLSHIAAQIYDLWTGIQWGAQVCFADPDALKGTLVNTLREVEPTSHMGVPRVWEKIMERIQEVAAQSGFIRRKMLLWAMSVTLEQNLTCPSNDLKPFTSRLADYLVLARVRQALGFAKCQKNFYGAAPMTAETQRFFLGLNIRLYAGYGLSESTGPHFMSSPYNYRLYSSGRVVPGCRVKLVNQDADGIGEICLWGRTIFMGYLNMEDKTCEAIDSEGWLHTGDMGRLDADGFLYITGRLKELIITAGGENVPPVPIEEAVKMELPIISSAMLIGDQRKFLSMLLTLKCTLDPETSEPTDSLTEQAVEFCQRVGSKASTVSEIVGQRDEAVYQAIHEGIQRVNANAAARPYHIQKWAILQRDFSISGGELGPTMKLKRLTVLEKYKDIIDSFYQEQKQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FCY5-1", "uniprot_id": "E7FCY5_DANRE", "id": "E7FCY5-1", "name": "Long-chain-fatty-acid--CoA ligase ACSBG1", "aln": "---------------------------------------------MTD--LLGQIVGDGLLEKNVIEEVLACAKLAPAQSLWTTEASGSVQLRMDEHCPEQPITVHQMFYNSVQKYGNLTALASKRGNKWEKATFLEYYHLCRMAAKGFLKLGLEQFHGVAILGFNSAEWFIAAVGTVFAGGIMAGIYTTNSPDACLHVANDSRANVIVVENQKQLDKIMQVKDKLPHLKAIVQYSGSLKEKLANLYSWEEFMELGLEVSDHELDEVISKQRANQCCVLIYTSGTTGSPKGVMLSHDNITWTAHHASRAGDMQPAEIRQESLVSYLPLSHIAAQIYDLWTGIKWGEQISFAQPDALKGTLVDSLREVTPTAHMGVPRVWEKIMEKIKEGISRCGYMKRKMVTWAMSVSLDANQRLKKDEEKSFLFTLAEKLILQKLRAELGFSSCVKFFSGAAPIGRETLQFFLGLNIRLYEAYGMSETSGPHFMSGPEAYQFLSCGKVVPGCQYKLININADGSGEVCFWGRNVFMGFLNLEDKTKEALDEDGWLRSGDLGKVDEDGFIYINGRIKELIITAGGENIPPLPIEDAVKQELSIISNAMLIGDERKFLSMLLTLKCTVNPETTEPTDILSLEAVEFCQRIGSQSTKLSDITGGKDKLVYKSIEDGIGQVNSKATSNAQRIQKWTILDKDFSVAGGELGPTMKLRRPVVLQMYHNEIENFYRE---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * *.: . ** .. *:. . .. ::****.*.* *:**:: *.: * ***:***::::***:* **. ** :***: :: :** :.* .*********:: *.********.***::**********::*****.**:** ::: *. ****:*:.****:**::: ..******:* *. . :*:**:*: **::*** **.:. ** :*..*:.******:*******.*******:*******::.*:***::***::** :********************:** *:.**:******:**::**** **:*************:*:* ::.*:::***: *****:*: * .: *.* **: *:* ::* ***:.* * * ****: ** :********** .**:**::******.* *:: *.*::****: **:* :*:* **:*:***.:***:**:**** **:*.:***::** *::* ***:**.**:***********:**:***:*** **.***.******:*************::*:*:: ** *: :*:*****:**:::.:*:* :*: **::*.:** :** :*::.. :****:**::***::**********:* .**: *:. *:.**:* ", "identical_positions": 390, "similar_positions": 194, "identity": "53.87%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110914-234", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JJW3-1", "uniprot_id": "ATPMK_RAT", "id": "Q9JJW3-1", "name": "ATP synthase F(0) complex subunit k, mitochondrial", "aln": "MAGPESDGQFQFTGIKKYFNSYTLTGRMNCVLATYGGIALLVLYFKLRPKKTPAVKAT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q78IK2-1", "uniprot_id": "ATPMK_MOUSE", "id": "Q78IK2-1", "name": "ATP synthase F(0) complex subunit k, mitochondrial", "aln": "MAGAESDGQFQFTGIKKYFNSYTLTGRMNCVLATYGGIALLVLYFKLRPKKTPAVKAT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96IX5-1", "uniprot_id": "ATPMK_HUMAN", "id": "Q96IX5-1", "name": "ATP synthase F(0) complex subunit k, mitochondrial", "aln": "MAGPESDAQYQFTGIKKYFNSYTLTGRMNCVLATYGSIALIVLYFKLRSKKTPAVKAT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "H0WES8-1", "uniprot_id": "H0WES8_DANRE", "id": "H0WES8-1", "name": "", "aln": "MGGHDAGSQHQFTGIAKYFNSYTITGRRNCVLATYASIAAIILFFKLKPKKQKAVTSS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2U8-1", "uniprot_id": "Q9W2U8_DROME", "id": "Q9W2U8-1", "name": "", "aln": "MAG-EGE---KLTGLSKIFNGTTMSGRANVAKATYAVMGLLIAYQVLKPKKK------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.* :. ::**: * **. *::** * . ***. :. :: : *:.** ", "identical_positions": 17, "similar_positions": 18, "identity": "29.31%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110914-248", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5EB63-1", "uniprot_id": "TM196_RAT", "id": "Q5EB63-1", "name": "Transmembrane protein 196", "aln": "MCTSGQIIGSLLVLSVLEIGLGVSSVAVGAVSFSLALREHTPQLGDSSP------FLLCGICGILCAKKKSGLVMILFSACCICGLIGGILNFQFLRAVTKKTSSLYPLHLASMSLACIGIGGCTVSSWLTCRLASYEQRRMFSEREHSLHHSHEMAEKEVTDNMSNGAPQLIFNGRVQSMF", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YWQ9-1", "uniprot_id": "TM196_MOUSE", "id": "D3YWQ9-1", "name": "Transmembrane protein 196", "aln": "MCTSGQIIGSLLVLSVLEIGLGVSSVAVGAVSFSLALREHTPQLGDSSP------FLLCGICGILCAKKKSGLVMILFSACCICGLIGGILNFQFLRAVTKKTSSLYPLHLASMSLACIGIGGCTVSSWLTCRLASYEQRRMFSEREHSLHHSHEMAEKEMTDNMSNGAPQLMFNGRVQSMF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5HYL7-1", "uniprot_id": "TM196_HUMAN", "id": "Q5HYL7-1", "name": "Transmembrane protein 196", "aln": "MCTSGQIIGSLLVLSVLEIGLGVSSVAVGAVSFSLALREHKPQLGDSSPVWSGVCFLLCGICGILCAKKKSGLVMILFSACCICGLIGGILNFQFLRAVTKKTSSLYPLHLASMSLACIGIGGCTLSSWLTCRLASYEQRRMFSEREHSLHHSHEMAEKEITDNMSNGGPQLIFNGRV----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RMB9-1", "uniprot_id": "A0A8M1RMB9_DANRE", "id": "A0A8M1RMB9-1", "name": "Transmembrane protein 196", "aln": "MCTKRSLVGSLLVLSVFHMGLGVSCVSLGVIGVTQTLWQQKSQHS-FSPIWSGACFLVCGLSGILCAKKRTGLTMILFSACCICGLIGGILNVQFVRAMMKRASSLHSFHLAFLCLDSLGILGCTLSTWLTCRLASSEQKRLFLERDLSLHHSVEMGEKVKAVCVAS----L----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***. .::********:.:*****.*::*.:..: :* ::..* . ** **:**:.*******::**.******************.**:**: *::***:.:*** :.* .:** ***:*:******** **:*:* **: ***** **.** : ::. * ", "identical_positions": 95, "similar_positions": 49, "identity": "52.2%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110914-91", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACE5-1", "uniprot_id": "INTU_RAT", "id": "D4ACE5-1", "name": "Protein inturned", "aln": "MADPARRDPRGRAPELPGDLSSQEEEEEESDSDAGASSLGSCSSASSD-TDLEPEWLDSVQRNGELFYLELSEDEEESLLPET--QTVNHVNHVRFSEKEVIIEEDDSRERK----KYEPKLRRFTKILKSKSLLPKRHHKKKSSNTGPVSILKHQSTQRTGVTVQQ-RYKDVTVYINPKKLTAIKAR--EQAKLLEVLVGVIHQTKWSWKRSGKQADGERLVVHGLVPGGSAMKSGQVLVGDVLVAVNDVDVTSENIERVLSCIPGPMQVKLTFENAYAVKKETAQPKKKKAQSS-------------TNDLVKLLCGSEADATQHSTLSIPHITMYLTLQLQSEVAREEQEMLYHYPVSEASQKLKSVRGIFLTLCDMLESVTGTQVTSSSLHVNGKQIHVAYLKESDKLLLIGLPAEEVPLPQLRNMTEDVAQTLKFMYGSLDSAFCQVENTPRLDHFFSLFFERALRPGKLHLSASPSAQQYDAASAVLLDNLPG-VRWLLLPQELKVELDTALSDLEAADFQELSEDYYDMRRLYTILGSSLFYKGYMVCSHLPKDDVVEIAAYCRQYCLLPLAAQQ---RIGQLIIWREVFPQHHLQPATDSDPEAFQEPEGRYFLLIVGLRHYMLCVLLEAGGCASKATGNPG-PDCIYVDQARATLHQLEGVESRIEEQLAATPGPCLSCADWFLAAP-REKADSLTTSPILGRLQGPSKTAASPTCRRTFFSDY---SFKARKPSPSRIGGGREP-GEGEENVGLSPHTTPDTVRKQRESEGSD---DNVALLKLARKKSTLPNPFHLGTS---KKELSEKE-LEVYNMM--KLTSGPENTLFHYVALETVQGIFITPTHEEVAQLGGSVHSQLIKNFHRCCLTIRAVFQQTLKVEKKKALSDGDHLESANSVSSLSPVKEHGVLFECSPENWTDQKKTPPVMSYWVVGRLFLNPKPQELYVCFHDSVSEIAIEMAFRLFFGLTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q059U7-1", "uniprot_id": "INTU_MOUSE", "id": "Q059U7-1", "name": "Protein inturned", "aln": "MAGLARGDSRGRPPELPGDLSSQEEEEEEGDSDAGASSLGSYSSASSD-TDVEPEWLDSVQKNGELFYLELSEDEEESLLPET--QTANHVNHVRFSDKEVIIEEDDSRERK----KSEPKLRRFTKILKSKSLLPRRHHKKSSSNNGPVSILKHQSSQKTGVTVQQ-RYKDVTVYINPRKLTAIKAR--EQVKLLEVLVGIIHQTKRSWKRSAKQADGERLVVHGLLPGGSAMKSGQVLVGDVLVAVNDVDVTSENIERVLSCIPGPMQVKLTFENAYAVKRETAQPQKKKAQSS-------------TQDLVKLLCGSEADAVQHSTLSIPHISMYLTLQLQSEAAREEQEILYHYPVSEASQKLKSVRGIFLTLCDMLESVTGTQVTSSSLHLNGKQIHVAYLKESDKLLLIGLPAEEVPLPQLRNMIEDVAQTLKFMYGSLDSAFCQVENAPRLDHFFSLFFERALRPGKLHLSGSPSAQQYAAASAVLLDNLPG-VRWLVLPQELKVELDTALSDLEAADFEELSEDYYDMRRLYTILGSSLFYKGYMVCSHLPKDDVIEIAAYCRQHCLLPLAAKQ---RIGQLIIWREVFPRHHLQPPSDSDPEAFQEPEGRYFLLVVGLRHYLLCVLLEAGGCASKATGNPG-PDCIYVDQVRATLHQLEGVDSRIEEQLATSPGPCLSCADWFLAAP-REKADSLTTSPILSRLQGPSKTAASPTCRRTFFSDY---SFKARKPSPSRIGGGREP-TEGEESAGLSPHATPDAVRKQRESEGSD---DNVALLKLARKKSTLPNPFHLGTS---KKELSEKE-LEVYDIM--KLTSGPENTLFHYVALETVQGIFITPTHEEVAQLGGSVHSQLIKNFHQCCLSIRAFFQQTLKEEKKKALSDGEHSEPTNSVSSLSPVKEHGVLFECSPENWTDQKKTPPVMSYWVVGRLFLNPKPQELYVCFHDSVSEIAIEMAFKLFFGLTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULD6-1", "uniprot_id": "INTU_HUMAN", "id": "Q9ULD6-1", "name": "Protein inturned", "aln": "MASVASCDSRPSSDELPGDPSSQEEDED-YDFEDRVSDSGSYSSASSDYDDLEPEWLDSVQKNGELFYLELSEDEEESLLPET--PTVN---HVRFSENEIIIEDD-YKERK----KYEPKLKQFTKILRRKRLLPKRCNKKNSNDNGPVSILKHQSNQKTGVIVQQ-RYKDVNVYVNPKKLTVIKAK--EQLKLLEVLVGIIHQTKWSWRRTGKQGDGERLVVHGLLPGGSAMKSGQVLIGDVLVAVNDVDVTTENIERVLSCIPGPMQVKLTFENAYDVKRETSHPRQKKTQSN-------------TSDLVKLLWGEEVEGIQQSGLNTPHIIMYLTLQLDSETSKEEQEILYHYPMSEASQKLKSVRGIFLTLCDMLENVTGTQVTSSSLLLNGKQIHVAYWKESDKLLLIGLPAEEVPLPRLRNMIENVIQTLKFMYGSLDSAFCQIENVPRLDHFFNLFFQRALQPAKLHSSASPSAQQYDASSAVLLDNLPG-VRWLTLPLEIKMELDMALSDLEAADFAELSEDYYDMRRLYTILGSSLFYKGYLICSHLPKDDLIDIAVYCRHYCLLPLAAKQ---RIGQLIIWREVFPQHHLRPLADSSTEVFPEPEGRYFLLVVGLKHYMLCVLLEAGGCASKAIGSPG-PDCVYVDQVKTTLHQLDGVDSRIDERLASSPVPCLSCADWFLTGS-REKTDSLTTSPILSRLQGTSKVATSPTCRRTLFGDY---SLKTRKPSPSCSSGGSDNGCEGGEDDGFSPHTTPDAVRKQRESQGSDGLEESGTLLKVTKKKSTLPNPFHLGNL---KKDLPEKE-LEIYNTV--KLTSGPENTLFHYVALETVQGIFITPTLEEVAQLSGSIHPQLIKNFHQCCLSIRAVFQQTLVEEKKKGLNSGDHSDSAKSVSSLNPVKEHGVLFECSPGNWTDQKKAPPVMAYWVVGRLFLHPKPQELYVCFHDSVTEIAIEIAFKLFFGLTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FCN8-1", "uniprot_id": "INTU_DANRE", "id": "E7FCN8-1", "name": "Protein inturned", "aln": "MFSTCS-DGRP----------FQSFSTNLEDFDS-IRSVLLYS-------DLEPEWLDDVQKNGQLFYLELSDGEEEALLAQVSANHSAATNHVRFSEKEAEIITDNAKRQANSSNKSEAKLKKLTKILRRKRRPSQRKAEGKDSSQRPASILKNQAGQRPGVVVQQQRLKDVCVYLNPKRLSSVSSSSADRGGLLEALLGVVHRPGG---NTGKR--GGKLIIHGLIPHSPASKCAEILIGDALVAVDDVEVTSENIERVLSCIPGPMQVRLTLETVCPAG--VSPESKVSASPQ-------------VSQLVRLLWGEDTIELQMSIADVPHIAMFLSLRLDSETQQDEQEIVYQYPQSEASAQLKAVRGIFLTLCDMLENVTGGQIISSSLWLQQQLVHVGYWKEESNLLVIAVPASRVPLLYLQTVIEGVVRTLKVMYGSLDRGFSDVENAPRLDHFFCLFFQQLIQPSRLIHS----SRTPDLYGSLFLDGLPA-VRWLTLPPDIKVEVDTVLSDFESSDFGDMSEDFYGMRRLYVILGSCLFYKGYLIANHLPKEDLLDVCLYCQHYCLLPLASEQ---RVAQLVVWREVFPQRRETRNSTAHP-GYCQPHARHFLLIVGLRHFMQCVLLEAGGCASSAVGRPT-PDSVYVDQVKATLLQLESLDAGIEERLSAPPTPCLSCADWFLPAGGRSQQDTIGSSPILNRLTAAIKPPSPGGIGRSLFGEAGTVGIRGRRASPQRSQ--SDSGSEGHADGTPASVARRDSLG----SGGSDGSLGSAGFLKMPRLK--HPNPFYLGSL---RKSLSERETEEMQNVL--QVTAGVENTLFHYVLMESVQGIFIAPTHTEIRHLSGSIHPQLIHNFQHCCLSIRQAFQQSLPTRDRRGPE-------RQSTAGLGPVKEHGVLFQCKPQNWTDQKKPAPTMTYWVIGRMLLEPVPQEFYVCFHDSVAEVPVEMAFRLSFGLAV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPH0-1", "uniprot_id": "INTU_DROME", "id": "Q9VPH0-1", "name": "Protein inturned", "aln": "----------------------MRKSPASLPSEAFSSSNSSLSNSYSD-GSDLANWEEYVSTDGSLFYMEYVRCEKTGVSAER---------RVEFMRRSLRLGKKSSRRQP--------------------HSNNQNQSQNQNQSHGPSRLDSQTEPQE----FRFSQFKTAAPDPKKLDLVITAADRFRFGRRSTAVESILG-----FRVLPFPDQPECLMVDGFVHDVSALQHG-IKRGDWFRSLNGIEVYASNVDELLKQFVEPTQVCLGFQSCGAASAVSPTDPGYNRNVREEQVCKVENFPMFTEKFEQMLITEGNFGIPGSSVDIRMPFAMLLLPPECYQHEQQQDSLYYFP-EIPDNFLFKARGSFLTLHAVLSELH-TQPLSSRLLVDQVQYHVNYRQLNGFLVLFAYAGGLCCAAECSLRSDELIGYIRFSLPGLVLESFNQEREPGNSSRLKLFLRHFCEIQRTRLVAR-------CHGHIRFEELLGQSRSLPLPKEAQLRIFDALSEMEAMDYRNWNDEPLTTHREFFIYGSALYYDGFLVASLLPPEVRVSVEGFLRCRGIFELLGAAPGIKVREMYVWEEIVLP---------------SATGRYFLTICTKNHLSLAVILKIFDAPDMAPDAVVGPSLFYIEEIQETLDHLVQCGIESLAMFWSVSNKRPEVLDATASES--RDQEKEPNNRLESFLKQKLTVLSPSVEEEAQLCSS----------------------LGGSSIHSLTPSEDESCRRRLTPIHGTAEDSDSGSDWENFAVQHPLHYGLNLGAESHSQSQMTESMWKEINNVVPVKISAGWKNSVLHYVYIDIANGSLFAPFTDSSENSNYLSEIRQACHIIHAVLQKSKHYRRHLSESSRAQTNS-----NGHSSHTVSLVKEHGMILEVSTQPKSDGQSQSSTSSRFVVVGRLFQSPAKEVYVCHRSDVPQNIVEMAFRLSFFSMG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . * . .:* : *. :*.***:* *: .: .: :*.* .. : . :.: :. : .... * : .: *. .: : * . : * : .: .:: *::.*:: .* : . : ** : :::.::* :.*::.:*. : * ** * ::. . . . . ...: ::* . * . * * :. .::*: :* :* . .. * .** **** :*..: * ** * :: ** * : .. *:::. .. : : ::. .* : *. * . : **:.: . : . : :: * . * * ** : ::.: .**::*: *: : .:: :* : * **.*:*.*:::.. ** : :.: : : :: * . :: :: :*.*:. .. .*:** : .* .*:*: .... * . *. .*::: : ** :* : : . . * . . :. .. : . * . :. .: : . * :. . *: . : : : ** :..:.* *: : : ::::* :*:::*** :: .:* :::* . : . . : :: :. * ::: * .: . :* :. *****:::: .. :* :. ... : :*: ::.. .:*.***.:..*.: :*:**:* * ", "identical_positions": 123, "similar_positions": 294, "identity": "12.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110919-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N7C3-1", "uniprot_id": "TRIMM_HUMAN", "id": "Q8N7C3-1", "name": "Probable E3 ubiquitin-protein ligase TRIML2", "aln": "------MSKRLSPQL----------QHNITEDAYCETHLEPTRLFCDVDQITLCSKCFQSQE--HKHHMVCGIQEAAEN---YRKLFQEILNTSREKLEAAKSILTDEQER------------------MAMIQEEEQNFKKMIESEYSMRLRLLNEECEQNLQRQQECISDLNLRETLLNQAIKLATELEEMF-QEMLQRLGRVGRENMEKLKESEARASEQVRSLLKLIVELEKKCGE-GTLALLKNAKYSLERSKSLLLEHLEPAHITDLSLCHIRGLSS-----------------MFRVLQRHLTLDPETAHPCLALSEDLRTMRLRHGQQD-----------------------GAGNPERLDFSAMVLAAESFTSGRHYWEVDVEKATR-WQVGIYHGSADAKGSTARASGEKVLLTGSVMGTEWTLWVFPPLKRLFLEKKLD--TVGVFLDCEHGQISFYNVTEMSLIYNFSHCAFQGALRPVFSLCIPNGDTSPDSLTILQHGPSCDATVSP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E9PW10-1", "uniprot_id": "E9PW10_MOUSE", "id": "E9PW10-1", "name": "", "aln": "------MSQAPKPQL----------PGN-TEDPNCGTHPEPSQFFSDDDQVIVCSKCFQSPE--HKQHGAYGIQEAAEY---YRTLLQETLVTLREKRDAATSLLAEERER------------------MVTIQEEEQRFKEMIEAEYKMRFQLLTEEEELAAYK-----VDLNLNGPNPDQLMKCGTELMQKS-QEMLQRLSHLGRENMEKLKASEVRLGEHLRSLQTMITDLEKNCGE-SAVALLQNAKCYLKRNESILLQSLEPAQITDLSFCLIIETSR-----------------VLLRLQRHITLDPGTAHPSLVLSEDLRSVGFRETPKT-----------------------GPGTTRRLDFSASVLGAESFTTGRHYWEVAVGQATQ-WQVGICD-CTERKDNIPGASGDKVLLMGSMMGTDCTLWVFPPLRKVCLRNQMY--KVGVFLDCECGQVSFYNVTEQSLIYSFSDLTFRGAIKPIFSLCIPNGDMSSDSLTVCLP------QTHP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3TL54-1", "uniprot_id": "TR43A_MOUSE", "id": "Q3TL54-1", "name": "Tripartite motif-containing protein 43A", "aln": "----MESDNLQDPQE-----------ETLTCSICQSIFMNPVYLRCGHKFCEACLLLSQEDI--KFPAYCPMCMQPFNQ--EYINDISLKKQVSIVRKKRLMKYLNSKEHK------------------CVTHKAKK---MIFCDKSKILLCHLCSDSQEHSGHTHCSIDVAVQEKMEELLKHMDSLWRRLKIQ-QNYVEIERRTTLWWLS-VKLREEVIKRVYGKQCPPLCEERDQHIE-CLRHQSNTTLEELRKSEATIVHERNQLIEVYRELMTMSQRPYQELLVQDLDDLFRRSKLAAKLDMPQGMIPRLHAHSIPGLTARLNSFRVKISFKHSIMFGYTSVRPFDIR-----LLHESTSLDSAETHRVSWGKKSFSRGKYYWEVDLKDHEQ-WTVGVRKDPWLRGRSYAATPTDLFLLECLRKEDHYILITRIGG-EHYIEKPVG--QVGVFLDCEGGYVSFVDVAKSSLILSYSPGTFHCAVRPFFSAVYT------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P86448-1", "uniprot_id": "TR43B_MOUSE", "id": "P86448-1", "name": "Tripartite motif-containing protein 43B", "aln": "----MESDNLQDPQE-----------ETLTCSICQGIFMNPVYLKCGHKFCEACLLLFQEDI--KFPAYCPMCMQPFNQ--EYINDISLKKQVSIVRKKRLMEYLNSEEHK------------------CVTHKAKK---MIFCDKSKILLCHLCSDSQEHSGHTHCSIDVAVQEKMEELLKHMDSLWRRLKIQ-QNYVEKERRTTLWWLKSMKLREEVIKRVYGKQCPPLSEERDQHIE-CLRHQSNTTLEELRKSEATIVHERNQLTEVYRELMTMSQRPYQELLVQDLDDLFRRSKLAAKLDMPQGMIPRLRAHSIPGLTARLNSFRVKISFKHSIMFGYTSLRPFDIR-----LLHESTSLDSAETHRVSWGKKSFSRGKYYWEVDLKDYRR-WTVGVCKDPWLRGRSYVATPTDLF-LECLRKDDHYILITRIGG-EHYIEKPVG--QVGVFLDCEGGYVSFVDVAKSSLILSYSPGTFHCAVRPFFSAVYT------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P86449-1", "uniprot_id": "TR43C_MOUSE", "id": "P86449-1", "name": "Tripartite motif-containing protein 43C", "aln": "----MESDNLQDPQE-----------ETLTCSICQGIFMDPVYLRCGHKFCETCLLLFQEDI--KFPAYCPTCRQPCNQ--RYINDISLKKQVFIVRKKRLMEYLNSEEHK------------------CVTHKAKK---MIFCDKSKILLCHLCSDSQEHSGHTHCSIDVAVQEKMEELLKHMDSLWQRLKIQ-QNYVEKERRMTLWWLKSVKLREEVIKRVYGKQCPPLSEERDQHIE-CLRHQSNTTLEELRKSEATIVHERNQLTEVYQELMTMSQRPYQELLVQDLDDLFRRSKLAAKVDMPQGMIPRLRAHSIPGLTARLNSFRVKISFKHSIMFGYNSVRPFDIR-----LLHESTSLDSAKTHRVSWGKKSFSRGKYYWEVDLKDYRR-WTVGVCKDPWLRGRSYVVTPTDIFLLECLRNKDHYILITRIGR-EHYIEKPVG--QVGVFLDCEGGYVSFVDVAKSSLILSYSPGTFHCAVRPFFFAAYT------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZLN6-1", "uniprot_id": "D3ZLN6_RAT", "id": "D3ZLN6-1", "name": "", "aln": "----MESDNLQASQ------------EILTCFICLGIFTDLVLTRCGHPFCRACLLLFSADT--QIPIHCPLCRHPSKP--NFRTAIPGKKLISIVRKERIKKYLSSEEHK------------------CMTHKERK---TIFCDENRVLLCQLCSKSQEHRGHRHCHIEEAVLKQMEKLLKQMESLLKKIQEL-QENLEAEKTMTDQWMDYVTLREEMIRTEYRKLYPSLDEEEAQHIE-CMKNQGNTNLEELRKSEAMMVHKRSQLMKVYQELMTMSQKPY-EVLQQGLDDLFRRCELVQ-LGMPQVMKPELSAHPNAGLTARFSFFKVKIFFQNLIILNCKMSQFFDIRRFTSRPCHQNTSLDSAGSYRASWGAMDFTTGKHYWELDLKDCEH-WAVGVCSNVWLSRSHKKIGSSGAFLLVCVKEGNHYSLFTTCPVSHHYIEKPTG--RVGVFLDCEGGCMSFLDVAKSSLIHSYHPEAFSLRVRPFFSTVYTRS----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IWZ4-1", "uniprot_id": "TRI48_HUMAN", "id": "Q8IWZ4-1", "name": "E3 ubiquitin-protein ligase TRIM48", "aln": "MSRRIIVGTLQRTQRNMNSGISQVFQRELTCPICMNYFIDPVTIDCGHSFCRPCFYLNWQDI--PILTQCFECIKTIQQR-NLKTNIRLKKMASLARKASLWLFLSSEEQM------------------CGIHRETK---KMFCEVDRSLLCLLCSSSQEHRYHRHCPAEWAAEEHWEKLLKKMQSLWEKACEN-QRNLNVETTRISHWKA------------FG--------------------------DILYRSESVLLH------------------------------------------MPQPLNLALRAGPITGLRDRLNQF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BVW3-1", "uniprot_id": "TRI14_MOUSE", "id": "Q8BVW3-1", "name": "Tripartite motif-containing protein 14", "aln": "--MASETTEARAPFQ----------PDGAYGWRCPEHSERPAELFCRRCGRCVCALCPVLGA--HRGHPVGLAEEEAVR---VQKLIQDCLECLATKKRQHADNIAHLEDAGER-------LKVYADSSKAWLTQKFTELRLLLDEEEVLAKKFIDKSTQLTLQVYREQAETCGKQIEVMDDFSTRVWGIGQEP-NPVQLLQAYIATKTEMGQQMSPSELSHPVPLSFEPVKNFFKEFVE-AIGNTLQTPMDTRLKENINCQLSNSSSTKPGALLKTSPSPER----------------ALFLKYARTPTLDPDTMHARLRLSPDGLTVRCSLLGRL-----------------------GPRPAPRFDALRQVLGRDGFAAGRHYWEVDVQEAGVGWWVGAAYPSLRRRGASAAARLGCNRESWCVKRYDLEYWAFHDGQRSRLRPRRDPHRLGVFLDYEAGILAFYDVAGGMSHLHTFHAAFQEPLYPALRLWEGPISIPRLP----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1R358-1", "uniprot_id": "F1R358_DANRE", "id": "F1R358-1", "name": "", "aln": "-----MMAQGSSSEG--------ALESELTCPVCLHLFLDPVTLPCAHSFCLNCLETPEKTSGSDQELCCPVCGQEHLSPESLPRNIKLKHIVESYKANSANGELQSSVEEKTINNEEKILTDCEQNETILDERSSRMNPVIASLQEKLCLVDNLMNREKAREAVVKAMHADLRKDVRSVMDEMEELVKMYRNTGVKLIEAELELREEAAGKRVQTLSDLQSQLRAAEGQINTLMDETDESCFSDRVQDVENQISCPMLESLRDVPDDLQLSSSLKKVREKIEHQNTQLRLGLGSAQRALRVVLNPSEVTFDPETVHPNLLLSEDLKTVSFSVTKQP-----------------------YPASSQRFTSFFQALSTQSFTRGEHLWS--FQAEGCPWVLSVCYGDLPRSG--SGSGLESSAGSWCLMYCDNLLRAYEKGKDTPLRRTPSLKRMEIRLSFTAGTLAFYSISDVSGDKTLLHTFKVSFTHPVYLAVRMMSGQPKARITLY------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * . : : : . . . : . . * . ", "identical_positions": 2, "similar_positions": 13, "identity": "0.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110919-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96BQ3-1", "uniprot_id": "TRI43_HUMAN", "id": "Q96BQ3-1", "name": "Tripartite motif-containing protein 43", "aln": "-------MDSDFSHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMDFKTNILLKNLVTIARKASLW---QFLSSEKQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHGAHKHHPIEEAAEEHR-EKLLKQMRILWKKIQENQRNLYEEG-RTAFLWRGNVVLRAQMIRNEYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCHKPDVELLQDLGDIVARSESVLLHMPQPVNPELTAGPITG------LVYRLNRFR-VEISFHFEVTNHNIRLFEDVRSWMFRRG----PLNSD-RSDYFAAWGARVFSFGKHYWELDVDNSCDWALGVCNNSW------------IRK--NSTMVNSEDIFLLLCLKVDNHFNLLTTSPVFPHYIEKPLGRVGVFLDFESGSVSFLNVTKSSLIWSYPAGSLTFPVRPFFYTGHR------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NCK2-1", "uniprot_id": "TR43B_HUMAN", "id": "A6NCK2-1", "name": "Tripartite motif-containing protein 43B", "aln": "-------MDSDFSHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMDFKTNILLKNLVTIARKASLW---QFLSSEKQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHGAHKHYPIEEAAEEDR-EKLLKQMRILWKKIQENQRNLYEER-RTAFLLRGDVVLRAQMIRNEYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCHKPEVELLQDLGDIVARSESVLLHMPQPVNPELTAGPITG------LVYRLNRFR-VEISFHFEVTNHNIRLFEDVRSWMFRRG----PLNSD-RSDYFAAWGARVFSFGKHYWELDVDNSCDWALGVCNNSW------------IRK--NSTMVNSEDIFLLLCLKVDNHFNLLTTSPVFPHYIEKPLGRVGVFLDFESGSVSFLNVTKSSLIWSYPAGSLTFPVRPFFYTGHR------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I1YAP6-1", "uniprot_id": "TRI77_HUMAN", "id": "I1YAP6-1", "name": "Tripartite motif-containing protein 77", "aln": "-------MASAITQCSTSELTCSICTDYLTDPVTICCGHRFCSPCLCLLWEDTLTPNCCPVCREISQQMYFKRIIFAEKQVIPTRESVPC---QLSSSAMLICRRHQEIKNLICETDRSLLCFLCSQSPRHATHKHYMTREADEYYR-KKLLIQMKSIWKKKQKNQRNLNRET-NIIGTWEVFINLRSMMISAEYPKVCQYLREEEQKHVESLAREGRIIFQQLKRSQTRMAKMGILLREMYEKLKEMSCKADVNLPQDLGDVMKRNEFLRLAMPQPVNPQLSAWTITG------VSERLNFFR-VYITLDRKICSNHKLLFEDLRHLQCSLDDTDMSCNPT-STQYTSSWGAQILSSGKHYWEVDVKDSCNWVIGLCREAW------------TKR--NDMRLDSEGIFLLLCLKVDDHFSLFSTSPLLPHYIPRPQGWLGVFLDYECGIVSFVNVAQSSLICSFLSRIFYFPLRPFICHGSK------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CI25-1", "uniprot_id": "TRI49_HUMAN", "id": "P0CI25-1", "name": "Tripartite motif-containing protein 49", "aln": "-------MNSGILQVFQGELICPLCMNYFIDPVTIDCGHSFCRPCFYLNWQDIPFLVQCSECTKSTEQINLKTNIHLKKMASLARKVSLW---LFLSSEEQMCGTHRETKKIFCEVDRSLLCLLCSSSQEHRYHRHRPIEWAAEEHR-EKLLQKMQSLWEKACENHRNLNVET-TRTRCWKDYVNLRLEAIRAEYQKMPAFHHEEEKHNLEMLKKKGKEIFHRLHLSKAKMAHRMEILRGMYEELNEMCHKPDVELLQAFGDILHRSESVLLHMPQPLNPELSAGPITG------LRDRLNQFR-VHITLHHEEANNDIFLYEILRSMCIGCDHQDVPYFTA-TPRSFLAWGVQTFTSGKYYWEVHVGDSWNWAFGVCNMYR------------KEKNQNEKIDGKAGLFLLGCVKNDIQCSLFTTSPLMLQYIPKPTSRVGLFLDCEAKTVSFVDVNQSSLIYTIPNCSFSPPLRPIFCCIHF------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CI26-1", "uniprot_id": "TR49C_HUMAN", "id": "P0CI26-1", "name": "Tripartite motif-containing protein 49C", "aln": "-------MNSGILQVFQGELICPLCMNYFIDPVTIDCGHSFCRPCFYLNWQDIPFLVQCSECTKSTEQINLKTNIHLKKMASLARKVSLW---LFLSSEEQMCGTHRETKKIFCEVDRSLLCLLCSSSQEHRYHRHRPIEWAAEEHR-EKLLQKMQSLWEKACENHRNLNVET-TRTRCWKDYVNLRLEAIRAEYQKMPAFHHEEEKHNLEMLKKKGKEIFHRLHLSKAKMAHRMEILRGMYEELNEMCHKPDVELLQAFGDILHRSESVLLHMPQPLNPELSAGPITG------LRDRLNQFR-VHITLHHEEANSDIFLYEILRSMCIGCDHQDVPYFTA-TPRSFLAWGVQTFTSGKYYWEVHVGDSWNWAFGVCNMYR------------KEKNQNEKIDGKEGLFLLGCIKNDIQCSLFTTSPLMLQYIPKPTSRVGLFLDCEAKTVSFVDVNQSSLIYTIPNCSFSPPLRPIFCCIHF------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "C9J1S8-1", "uniprot_id": "TR49D_HUMAN", "id": "C9J1S8-1", "name": "Tripartite motif-containing protein 49D", "aln": "-------MNSGISQVFQRELTCPICLNYFIDPVTIDCGHSFCRPCFYLNWQDIPILTQCFECLKTTQQRNLKTNIRLKKMASRARKASLW---LFLSSEEQMCGTHRETKKIFCEVDRSLLCLLCSSSLEHRYHRHCPAEWAAEEHR-EKLLKKMQSLWEKVCENQRNLNVET-TRISHWKDYVNVRLEAIRAEYQKMPAFHHEEEKHNLEMLKKKGKDIFHRLHLSKAKMAHRREILRGTYAELMKMCHKPDVELLQAFGDILHRSESVLLHMPQPLNLELRAGPITG------LRDRLNQFR-VDITLPHNEANSHIFRRGDLRSICIGCDRQNAPHITA-TPTSFLAWGAQTFTSGKYYWEVHVGDSWNWAFGVCNKYW------------KGTNQNGNIHGEEGLFSLGCVKNDIQCSLFTTSPLTLQYVPRPTNHVGLFLDCEARTVSFVDVNQSSPIHTIPNCSFSPPLRPIFCCVHL------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A3B3IT33-1", "uniprot_id": "TR51G_HUMAN", "id": "A0A3B3IT33-1", "name": "Tripartite motif-containing protein 51G", "aln": "-------MNSGILQVFQRELICPICMNYFIDPVTIDCGHSFCRPCFYLNWQDMAVLAQCSKCKKTTRQRNLKTNICLKNMASIARKASLR---QFLSSEEQICGTHRETKEMFCEVDKSLLCLLCSNSQEHRNHRHCPTEWAAEERR-EELLRKMQSLWRKMCENHRNLNMAT-NRIRCWKDYVSLRIEAIRAEYHKMVAFFHEEEQRHLERLQKEGEDIFQQLNESKARMEHSRELLRGMYEDLRQMCHKAVVELFQSFGDILQRYESLLLQVSEPVNPEFSAGPIIG------LMDRLKGFR-VYLTLQHARASSHIFLHGDLRSMKVGCDPQHDPNITD-KSECFLQWGADFFISGKFYWEFNMGHSWNWAFGVCNNYW------------KEKRQNDMIDGEVGLFLLGCVKEDTHCSLFTTSPLVMQYVPRPTDTVGLFLDCEGRTVSFVDVDRSSLIYTIPNCSFSPPLWPIICCSHF------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NI03-1", "uniprot_id": "TR64B_HUMAN", "id": "A6NI03-1", "name": "Tripartite motif-containing protein 64B", "aln": "-------MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKTSEKPNFNTNLVLKKLSSLARQTRPQ---NINSSDN-ICVLHEETKELFCEADKRLLCGPCSESPEHMAHSHSPIGWAAEECR-EKLIKEMDYLWEINQETRNNLNQET-STFHSLKDYVSVRKRIITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCHMPDVVLLQDVRNVSARTDLAQMQKPQPVNPELTSWCITG------VLDMLNNFR-VDSALSTEMIPCYISLSEDVRYVIFGDDHLSAPTDPQ-GVDSFAVWGAQAFTSGKHYWEVDVTLSSNWILGVCRDSR------------TAD--ANFVIDSDERFFLISSKRSNHYSLSTNSPPLIQYVQRPLGRVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFFCFGCT------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NGJ6-1", "uniprot_id": "TRI64_HUMAN", "id": "A6NGJ6-1", "name": "Tripartite motif-containing protein 64", "aln": "-------MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKISEKPNFNTNVVLKKLSSLARQTRPQ---NINSSDN-ICVLHEETKELFCEADKRLLCGPCSESPEHMAHSHSPIGWAAEECR-EKLIKEMDYLWEINQETRNNLNQET-RTFHSLKDYVSVRKRIITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCHVPDVELLQDVRNVSARTDLAQMQKPQPVNPELTSWCITG------VLDMLNNFR-VDSALSTEMIPCYISLSEDVRYVIFGDDHLSAPTDPQ-GVDSFAVWGAQAFTSGKHYWEVDVTLSSNWILGVCQDSR------------TAD--ANFVIDSDERFFLISSKRSNHYSLSTNSPPLIQYVQRPLGQVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFFCFGCT------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NLI5-1", "uniprot_id": "TR64C_HUMAN", "id": "A6NLI5-1", "name": "Tripartite motif-containing protein 64C", "aln": "-------MDSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEGRAPMRCPLCRKISEKPNFNTNVALKKLASLARQTRPQ---NINSSDN-ICVLHEETKELFCEADKRLLCGPCSESPEHMAHSHSPIGWAAEECRVQKLIKEMDYLWKINQETQNNLNQET-SKFCSLVDYVSLRKVIITIQYQKMHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELWETYHMPDVELLQDVGNISARTDLAQMPKPQPVNPELTSWCITG------VLDMLNNFR-VDNALSTEMTPCYISLSEDVRRVIFGDDHRSAPMDPQ-GVESFAVWCAQAFTSGKHYWEVDVTHSSNWILGVCRDSR------------TAD--TNIVIDSDKTFFSISSKTSNHYSLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFFCFGCT------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A221-1", "uniprot_id": "D4A221_RAT", "id": "D4A221-1", "name": "", "aln": "MSVHEKISTADLMENLREELTCFICLDYFSSPVTTECGHSFCLTCLLKSWEEHNTPLSCPECWRTLGAPHFQANERLGRLANIGRQLRCQ---VLQSEDEQSNSGRTPGPSRVFSDDEQSVINFSPPN--HGMNRAYFSSEAEEQHK-EKLQDIVNILRKRKKEAQAILNHEKERVMLCKQEETKTCKQVVVSEYMKMHQFLKEEEQLQLQLLEKEEKENVKKLRENEIHLTQQVRRINKMIGRIESICQNLTLESFEEVRGAMDRYESLLFQCPETTITELSLCRITG------MREMLRKFS-TDITLDPATANAYLLLSDDLKSVRYGGTKQQLPDNPERFDQSATVLGAQIFTCGRHYWEVEVGKKTEWEVGICKDSV------------NRK--GNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVHKVGVFLDYDSGHIAFYNVTDESLIYSFPPSSFHEALRPIFSPCLPNEGTNTDPLIICHI----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N9V2-1", "uniprot_id": "TRIML_HUMAN", "id": "Q8N9V2-1", "name": "Probable E3 ubiquitin-protein ligase TRIML1", "aln": "------MSTADLMENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEEHNTPLSCPECWRTLEGPHFQSNERLGRLASIARQLRSQ---VLQSEDEQGSYGRMPTTAKALSDDEQGGSAFVAQS--HGANRVHLSSEAEEHHR-EKLQEILNLLRVRRKEAQAVLTHEKERVKLC-QEETKTCKQVVVSEYMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMIAQIESSSQSSAFESLEEVRGALERSEPLLLQCPEATTTELSLCRITG------MKEMLRKFS-TEITLDPATANAYLVLSEDLKSVKYGGSRQQLPDNPERFDQSATVLGTQIFTSGRHYWEVEVGNKTEWEVGICKDSV------------SRK--GNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVCKVGVFLDYESGHIAFYNGTDESLIYSFPQASFQEALRPIFSPCLPNEGTNTDPLTICSLNSHV------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RKG6-1", "uniprot_id": "TRI35_RAT", "id": "Q5RKG6-1", "name": "E3 ubiquitin-protein ligase TRIM35", "aln": "-MEPGPSVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRRCVSGCWEVQTTPS-CPVCKERAVPGELRTNHTLNNLVETLLREEAEGARWTGRRSPRPCRAHRAPLTLFCVEDKELLCCACQADARHQEHRVQPIKDTAQDFR--AKCKNMEHVLREKAKSFWALRRTYEAIAKHNEVQTTWLEGRIRDEFDKLRDFLRVEEQATVDAMKEESRKKHLLAEEKMKQLAEQTEALAREIERLQMEMKEDDMTFLMKHKSRKRRLFCTVEPAPLQPGLLMDACKYLESLQYRVWKKMLGSVESVPFSLDPNTAAGWLKVADDLTSVINHGYRVQVENPER-FSSAPCLLGSQVFSKGSHSWEVDVGGLPSWRVGVVRVQAHAQAQAQADVGGEGHSHSCYHDTRSGFWYLCRTQGVDGDHCMTSDTATAPLVQAMPRRLRVELECEEGELSFYDSERHCHLYTFHAH--FGEVRPYFYLGASRGDGPPEPLRICHLRVSIKEELDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C006-1", "uniprot_id": "TRI35_MOUSE", "id": "Q8C006-1", "name": "E3 ubiquitin-protein ligase TRIM35", "aln": "-MEPGPSVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRRCVSGCWEVQTTPS-CPVCKERAVPGELRTNHTLNNLVETLLREEAEGARWTGRRSPRPCRAHRAPLTLFCLEDKELLCCACQADARHQEHRVQPIKDTAQDFR--AKCKNMEHVLREKAKAFWALRRTYEAIAKHNEVQTTWLEGRIRDEFDKLRDFLRVEEQATLDAMKEESRKKHLQAEEKMKQLAEQTEALAREIERLQMEMKEDDMTFLMKHKSRKRRLFCTVEPAPLQPGLLMDACKYLESLQYRVWKKMLGSVESVPFSLDPNTAAGWLKVADDLTSVINHGYRVQVENPER-FSSAPCLLGSQVFSKGSHSWEVDVGGLPTWRVGVVRVQAHAQAQAQADVGGEGHSHSCYHDTRSGFWYLCRTQGVDGDHCMTSDTATAPLVQAMPRRLRVELECEEGELSFYDSERHCHLYTFHAH--FGEVRPYFYLGASRGDGPPEPLRICHLRVSIKEELDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPQ4-1", "uniprot_id": "TRI35_HUMAN", "id": "Q9UPQ4-1", "name": "E3 ubiquitin-protein ligase TRIM35", "aln": "-MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPT-CPVCKDRASPADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQPVKDTAHDFR--AKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQVENPER-FSSAPCLLGSRVFSQGSHAWEVALGGLQSWRVGVVRVRQ--------DSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFHAR--FGEVRPYFYLGGARGAGPPEPLRICPLHISVKEELDG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PZW6-1", "uniprot_id": "A0A8M1PZW6_DANRE", "id": "A0A8M1PZW6-1", "name": "", "aln": "-----------MSSQAEYDYICPVCHEVFRVPVILPCGHSFCQRCVRQFWS-GRRARECPVCRRSCRHLQPVVNLALKNLCEEFETRRKR------SRPEDMCGLHQEKLKLFCLQDNQPVCVVCFTSQQHDQHTLRPVAEAAAPRK--DQLSAALKILQEKLQHREKTKEELQKTLQHIRAQAEQTERQIRLQFQKLHQFLRDEEEASVSAVREEEEEKQQMMKEKLEDINKHISDLSHAIRDTEESMSRSSIRFLQEFTVSMERVQISPPDPQIPAGALINESRHLGNLMHRVWRKMENIVQHTPVVLDPNTAHPDLLVSADLSSVRWSWSKRALPDNAERFDHHPCVLASEGVRSGTLSWAVEVRQSSDWTLGVTTELN--------------------QRKGWDFFSADVWSVCYDEYSVSERPVFGVRVKQRLERVRVDLDYDGGTISFSDAVNNTHIHTFSSN-FTHTLIPFFSCYTIFNLKILPSNSQQQLNTNAELTP--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :* : : .* * * ** *. . * * . : *. . * : : : : : :: *: **: :. : .: . . : . : . * : . . : : . * * . : * .*: : . . : : : *: : ::* : : : * : ", "identical_positions": 23, "similar_positions": 55, "identity": "4.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110920-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96BQ3-1", "uniprot_id": "TRI43_HUMAN", "id": "Q96BQ3-1", "name": "Tripartite motif-containing protein 43", "aln": "-------MDSDFSHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMDFKTNILLKNLVTIARKASLW---QFLSSEKQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHGAHKHHPIEEAAEEHR-EKLLKQMRILWKKIQENQRNLYEEG-RTAFLWRGNVVLRAQMIRNEYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCHKPDVELLQDLGDIVARSESVLLHMPQPVNPELTAGPITG------LVYRLNRFR-VEISFHFEVTNHNIRLFEDVRSWMFRRG----PLNSD-RSDYFAAWGARVFSFGKHYWELDVDNSCDWALGVCNNSW------------IRK--NSTMVNSEDIFLLLCLKVDNHFNLLTTSPVFPHYIEKPLGRVGVFLDFESGSVSFLNVTKSSLIWSYPAGSLTFPVRPFFYTGHR------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NCK2-1", "uniprot_id": "TR43B_HUMAN", "id": "A6NCK2-1", "name": "Tripartite motif-containing protein 43B", "aln": "-------MDSDFSHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMDFKTNILLKNLVTIARKASLW---QFLSSEKQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHGAHKHYPIEEAAEEDR-EKLLKQMRILWKKIQENQRNLYEER-RTAFLLRGDVVLRAQMIRNEYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCHKPEVELLQDLGDIVARSESVLLHMPQPVNPELTAGPITG------LVYRLNRFR-VEISFHFEVTNHNIRLFEDVRSWMFRRG----PLNSD-RSDYFAAWGARVFSFGKHYWELDVDNSCDWALGVCNNSW------------IRK--NSTMVNSEDIFLLLCLKVDNHFNLLTTSPVFPHYIEKPLGRVGVFLDFESGSVSFLNVTKSSLIWSYPAGSLTFPVRPFFYTGHR------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CI25-1", "uniprot_id": "TRI49_HUMAN", "id": "P0CI25-1", "name": "Tripartite motif-containing protein 49", "aln": "-------MNSGILQVFQGELICPLCMNYFIDPVTIDCGHSFCRPCFYLNWQDIPFLVQCSECTKSTEQINLKTNIHLKKMASLARKVSLW---LFLSSEEQMCGTHRETKKIFCEVDRSLLCLLCSSSQEHRYHRHRPIEWAAEEHR-EKLLQKMQSLWEKACENHRNLNVET-TRTRCWKDYVNLRLEAIRAEYQKMPAFHHEEEKHNLEMLKKKGKEIFHRLHLSKAKMAHRMEILRGMYEELNEMCHKPDVELLQAFGDILHRSESVLLHMPQPLNPELSAGPITG------LRDRLNQFR-VHITLHHEEANNDIFLYEILRSMCIGCDHQDVPYFTA-TPRSFLAWGVQTFTSGKYYWEVHVGDSWNWAFGVCNMYR------------KEKNQNEKIDGKAGLFLLGCVKNDIQCSLFTTSPLMLQYIPKPTSRVGLFLDCEAKTVSFVDVNQSSLIYTIPNCSFSPPLRPIFCCIHF------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CI26-1", "uniprot_id": "TR49C_HUMAN", "id": "P0CI26-1", "name": "Tripartite motif-containing protein 49C", "aln": "-------MNSGILQVFQGELICPLCMNYFIDPVTIDCGHSFCRPCFYLNWQDIPFLVQCSECTKSTEQINLKTNIHLKKMASLARKVSLW---LFLSSEEQMCGTHRETKKIFCEVDRSLLCLLCSSSQEHRYHRHRPIEWAAEEHR-EKLLQKMQSLWEKACENHRNLNVET-TRTRCWKDYVNLRLEAIRAEYQKMPAFHHEEEKHNLEMLKKKGKEIFHRLHLSKAKMAHRMEILRGMYEELNEMCHKPDVELLQAFGDILHRSESVLLHMPQPLNPELSAGPITG------LRDRLNQFR-VHITLHHEEANSDIFLYEILRSMCIGCDHQDVPYFTA-TPRSFLAWGVQTFTSGKYYWEVHVGDSWNWAFGVCNMYR------------KEKNQNEKIDGKEGLFLLGCIKNDIQCSLFTTSPLMLQYIPKPTSRVGLFLDCEAKTVSFVDVNQSSLIYTIPNCSFSPPLRPIFCCIHF------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "C9J1S8-1", "uniprot_id": "TR49D_HUMAN", "id": "C9J1S8-1", "name": "Tripartite motif-containing protein 49D", "aln": "-------MNSGISQVFQRELTCPICLNYFIDPVTIDCGHSFCRPCFYLNWQDIPILTQCFECLKTTQQRNLKTNIRLKKMASRARKASLW---LFLSSEEQMCGTHRETKKIFCEVDRSLLCLLCSSSLEHRYHRHCPAEWAAEEHR-EKLLKKMQSLWEKVCENQRNLNVET-TRISHWKDYVNVRLEAIRAEYQKMPAFHHEEEKHNLEMLKKKGKDIFHRLHLSKAKMAHRREILRGTYAELMKMCHKPDVELLQAFGDILHRSESVLLHMPQPLNLELRAGPITG------LRDRLNQFR-VDITLPHNEANSHIFRRGDLRSICIGCDRQNAPHITA-TPTSFLAWGAQTFTSGKYYWEVHVGDSWNWAFGVCNKYW------------KGTNQNGNIHGEEGLFSLGCVKNDIQCSLFTTSPLTLQYVPRPTNHVGLFLDCEARTVSFVDVNQSSPIHTIPNCSFSPPLRPIFCCVHL------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A3B3IT33-1", "uniprot_id": "TR51G_HUMAN", "id": "A0A3B3IT33-1", "name": "Tripartite motif-containing protein 51G", "aln": "-------MNSGILQVFQRELICPICMNYFIDPVTIDCGHSFCRPCFYLNWQDMAVLAQCSKCKKTTRQRNLKTNICLKNMASIARKASLR---QFLSSEEQICGTHRETKEMFCEVDKSLLCLLCSNSQEHRNHRHCPTEWAAEERR-EELLRKMQSLWRKMCENHRNLNMAT-NRIRCWKDYVSLRIEAIRAEYHKMVAFFHEEEQRHLERLQKEGEDIFQQLNESKARMEHSRELLRGMYEDLRQMCHKAVVELFQSFGDILQRYESLLLQVSEPVNPEFSAGPIIG------LMDRLKGFR-VYLTLQHARASSHIFLHGDLRSMKVGCDPQHDPNITD-KSECFLQWGADFFISGKFYWEFNMGHSWNWAFGVCNNYW------------KEKRQNDMIDGEVGLFLLGCVKEDTHCSLFTTSPLVMQYVPRPTDTVGLFLDCEGRTVSFVDVDRSSLIYTIPNCSFSPPLWPIICCSHF------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I1YAP6-1", "uniprot_id": "TRI77_HUMAN", "id": "I1YAP6-1", "name": "Tripartite motif-containing protein 77", "aln": "-------MASAITQCSTSELTCSICTDYLTDPVTICCGHRFCSPCLCLLWEDTLTPNCCPVCREISQQMYFKRIIFAEKQVIPTRESVPC---QLSSSAMLICRRHQEIKNLICETDRSLLCFLCSQSPRHATHKHYMTREADEYYR-KKLLIQMKSIWKKKQKNQRNLNRET-NIIGTWEVFINLRSMMISAEYPKVCQYLREEEQKHVESLAREGRIIFQQLKRSQTRMAKMGILLREMYEKLKEMSCKADVNLPQDLGDVMKRNEFLRLAMPQPVNPQLSAWTITG------VSERLNFFR-VYITLDRKICSNHKLLFEDLRHLQCSLDDTDMSCNPT-STQYTSSWGAQILSSGKHYWEVDVKDSCNWVIGLCREAW------------TKR--NDMRLDSEGIFLLLCLKVDDHFSLFSTSPLLPHYIPRPQGWLGVFLDYECGIVSFVNVAQSSLICSFLSRIFYFPLRPFICHGSK------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NI03-1", "uniprot_id": "TR64B_HUMAN", "id": "A6NI03-1", "name": "Tripartite motif-containing protein 64B", "aln": "-------MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKTSEKPNFNTNLVLKKLSSLARQTRPQ---NINSSDN-ICVLHEETKELFCEADKRLLCGPCSESPEHMAHSHSPIGWAAEECR-EKLIKEMDYLWEINQETRNNLNQET-STFHSLKDYVSVRKRIITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCHMPDVVLLQDVRNVSARTDLAQMQKPQPVNPELTSWCITG------VLDMLNNFR-VDSALSTEMIPCYISLSEDVRYVIFGDDHLSAPTDPQ-GVDSFAVWGAQAFTSGKHYWEVDVTLSSNWILGVCRDSR------------TAD--ANFVIDSDERFFLISSKRSNHYSLSTNSPPLIQYVQRPLGRVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFFCFGCT------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NGJ6-1", "uniprot_id": "TRI64_HUMAN", "id": "A6NGJ6-1", "name": "Tripartite motif-containing protein 64", "aln": "-------MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKISEKPNFNTNVVLKKLSSLARQTRPQ---NINSSDN-ICVLHEETKELFCEADKRLLCGPCSESPEHMAHSHSPIGWAAEECR-EKLIKEMDYLWEINQETRNNLNQET-RTFHSLKDYVSVRKRIITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCHVPDVELLQDVRNVSARTDLAQMQKPQPVNPELTSWCITG------VLDMLNNFR-VDSALSTEMIPCYISLSEDVRYVIFGDDHLSAPTDPQ-GVDSFAVWGAQAFTSGKHYWEVDVTLSSNWILGVCQDSR------------TAD--ANFVIDSDERFFLISSKRSNHYSLSTNSPPLIQYVQRPLGQVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFFCFGCT------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NLI5-1", "uniprot_id": "TR64C_HUMAN", "id": "A6NLI5-1", "name": "Tripartite motif-containing protein 64C", "aln": "-------MDSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEGRAPMRCPLCRKISEKPNFNTNVALKKLASLARQTRPQ---NINSSDN-ICVLHEETKELFCEADKRLLCGPCSESPEHMAHSHSPIGWAAEECRVQKLIKEMDYLWKINQETQNNLNQET-SKFCSLVDYVSLRKVIITIQYQKMHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELWETYHMPDVELLQDVGNISARTDLAQMPKPQPVNPELTSWCITG------VLDMLNNFR-VDNALSTEMTPCYISLSEDVRRVIFGDDHRSAPMDPQ-GVESFAVWCAQAFTSGKHYWEVDVTHSSNWILGVCRDSR------------TAD--TNIVIDSDKTFFSISSKTSNHYSLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFFCFGCT------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D4A221-1", "uniprot_id": "D4A221_RAT", "id": "D4A221-1", "name": "", "aln": "MSVHEKISTADLMENLREELTCFICLDYFSSPVTTECGHSFCLTCLLKSWEEHNTPLSCPECWRTLGAPHFQANERLGRLANIGRQLRCQ---VLQSEDEQSNSGRTPGPSRVFSDDEQSVINFSPPN--HGMNRAYFSSEAEEQHK-EKLQDIVNILRKRKKEAQAILNHEKERVMLCKQEETKTCKQVVVSEYMKMHQFLKEEEQLQLQLLEKEEKENVKKLRENEIHLTQQVRRINKMIGRIESICQNLTLESFEEVRGAMDRYESLLFQCPETTITELSLCRITG------MREMLRKFS-TDITLDPATANAYLLLSDDLKSVRYGGTKQQLPDNPERFDQSATVLGAQIFTCGRHYWEVEVGKKTEWEVGICKDSV------------NRK--GNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVHKVGVFLDYDSGHIAFYNVTDESLIYSFPPSSFHEALRPIFSPCLPNEGTNTDPLIICHI----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N9V2-1", "uniprot_id": "TRIML_HUMAN", "id": "Q8N9V2-1", "name": "Probable E3 ubiquitin-protein ligase TRIML1", "aln": "------MSTADLMENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEEHNTPLSCPECWRTLEGPHFQSNERLGRLASIARQLRSQ---VLQSEDEQGSYGRMPTTAKALSDDEQGGSAFVAQS--HGANRVHLSSEAEEHHR-EKLQEILNLLRVRRKEAQAVLTHEKERVKLC-QEETKTCKQVVVSEYMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMIAQIESSSQSSAFESLEEVRGALERSEPLLLQCPEATTTELSLCRITG------MKEMLRKFS-TEITLDPATANAYLVLSEDLKSVKYGGSRQQLPDNPERFDQSATVLGTQIFTSGRHYWEVEVGNKTEWEVGICKDSV------------SRK--GNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVCKVGVFLDYESGHIAFYNGTDESLIYSFPQASFQEALRPIFSPCLPNEGTNTDPLTICSLNSHV------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5RKG6-1", "uniprot_id": "TRI35_RAT", "id": "Q5RKG6-1", "name": "E3 ubiquitin-protein ligase TRIM35", "aln": "-MEPGPSVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRRCVSGCWEVQTTPS-CPVCKERAVPGELRTNHTLNNLVETLLREEAEGARWTGRRSPRPCRAHRAPLTLFCVEDKELLCCACQADARHQEHRVQPIKDTAQDFR--AKCKNMEHVLREKAKSFWALRRTYEAIAKHNEVQTTWLEGRIRDEFDKLRDFLRVEEQATVDAMKEESRKKHLLAEEKMKQLAEQTEALAREIERLQMEMKEDDMTFLMKHKSRKRRLFCTVEPAPLQPGLLMDACKYLESLQYRVWKKMLGSVESVPFSLDPNTAAGWLKVADDLTSVINHGYRVQVENPER-FSSAPCLLGSQVFSKGSHSWEVDVGGLPSWRVGVVRVQAHAQAQAQADVGGEGHSHSCYHDTRSGFWYLCRTQGVDGDHCMTSDTATAPLVQAMPRRLRVELECEEGELSFYDSERHCHLYTFHAH--FGEVRPYFYLGASRGDGPPEPLRICHLRVSIKEELDI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C006-1", "uniprot_id": "TRI35_MOUSE", "id": "Q8C006-1", "name": "E3 ubiquitin-protein ligase TRIM35", "aln": "-MEPGPSVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRRCVSGCWEVQTTPS-CPVCKERAVPGELRTNHTLNNLVETLLREEAEGARWTGRRSPRPCRAHRAPLTLFCLEDKELLCCACQADARHQEHRVQPIKDTAQDFR--AKCKNMEHVLREKAKAFWALRRTYEAIAKHNEVQTTWLEGRIRDEFDKLRDFLRVEEQATLDAMKEESRKKHLQAEEKMKQLAEQTEALAREIERLQMEMKEDDMTFLMKHKSRKRRLFCTVEPAPLQPGLLMDACKYLESLQYRVWKKMLGSVESVPFSLDPNTAAGWLKVADDLTSVINHGYRVQVENPER-FSSAPCLLGSQVFSKGSHSWEVDVGGLPTWRVGVVRVQAHAQAQAQADVGGEGHSHSCYHDTRSGFWYLCRTQGVDGDHCMTSDTATAPLVQAMPRRLRVELECEEGELSFYDSERHCHLYTFHAH--FGEVRPYFYLGASRGDGPPEPLRICHLRVSIKEELDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPQ4-1", "uniprot_id": "TRI35_HUMAN", "id": "Q9UPQ4-1", "name": "E3 ubiquitin-protein ligase TRIM35", "aln": "-MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPT-CPVCKDRASPADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQPVKDTAHDFR--AKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQVENPER-FSSAPCLLGSRVFSQGSHAWEVALGGLQSWRVGVVRVRQ--------DSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFHAR--FGEVRPYFYLGGARGAGPPEPLRICPLHISVKEELDG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TBF6-1", "uniprot_id": "A0A8N7TBF6_DANRE", "id": "A0A8N7TBF6-1", "name": "", "aln": "--------MATKQSHLAEDLSCPICGSILQKPVVLFCRHRFCKPCLESLWNGG-GSCECPLCCQPSSMGELVVNTVLEKTCEGFLEKCKN--------DPLACREHGETLTLFCLEHLEPTCSKCKSSMNHQGHRLYPLNEASHDCK--EELKNALKPLQEKLKLFRKVKLTCEHAVNHIKNQAENTERQIREEFEALHQFLRDEEASRLSMLKQEREQKRQMMNEKIEDLENDITSLTNTIRIIEQEMRSQDIPFLKNYKDTIKRTWRIPQDPEMIAGSLLDIAKHLGSLKFKVWERMLEIIQYTPVTLDPNTAASCFLLSEDLTTLQCCSQTFKLPENPERFNVGAEVLGYEGFSSGRHSWDVEVKNNTYWVIGVASASIS-------------RKGKHVLTPAEGFWTIR---LRNGEYKACTAPWSPLTMTKEPQVVRVVLDMNRSRVTFYDLRERTPLFTYTDIITPRAF-PYFCSACKEYPLKVLPAWISIKSE--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :* * :* . : ..*. * * ** *. : * * : . . : . . * : : . : : : : :: : ** :. : .: . . : . : : . . * : * . . :: : : * . *:. : * .*: : . . : : : *: : ::* : : . * : ", "identical_positions": 23, "similar_positions": 66, "identity": "4.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110920-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96BQ3-1", "uniprot_id": "TRI43_HUMAN", "id": "Q96BQ3-1", "name": "Tripartite motif-containing protein 43", "aln": "----------------------------------------------MDSDFSHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMDFKTNILLKNLVTIARKASLW---QFLSSEKQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHGAHKHHPIEEAAEEHR-EKLLKQMRILWKKIQENQRNLYEEGRTAFLWRGNVVLRAQ-MIRNEYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCHKPDVELLQDLGDIVARSESVLLHM-PQPVNPELTAGPITGLVYRLNRFR---------VEISFH-FEVTNHNIRLFEDVRSWMFRRG----PLNSDRSDYFAAWGARVFSFGKHYWELDVDNSCDWALGVCNNSWIRKN-STMVN------------SED-IFLLLCLKVDNHFNLLTTSPVFPHYIEKPLGRVGVFLDFESGSVSFLNVTKSSLIWSYPAGSLTFPVRPFFYTGHR------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NCK2-1", "uniprot_id": "TR43B_HUMAN", "id": "A6NCK2-1", "name": "Tripartite motif-containing protein 43B", "aln": "----------------------------------------------MDSDFSHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMDFKTNILLKNLVTIARKASLW---QFLSSEKQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHGAHKHYPIEEAAEEDR-EKLLKQMRILWKKIQENQRNLYEERRTAFLLRGDVVLRAQ-MIRNEYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCHKPEVELLQDLGDIVARSESVLLHM-PQPVNPELTAGPITGLVYRLNRFR---------VEISFH-FEVTNHNIRLFEDVRSWMFRRG----PLNSDRSDYFAAWGARVFSFGKHYWELDVDNSCDWALGVCNNSWIRKN-STMVN------------SED-IFLLLCLKVDNHFNLLTTSPVFPHYIEKPLGRVGVFLDFESGSVSFLNVTKSSLIWSYPAGSLTFPVRPFFYTGHR------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A3B3IT33-1", "uniprot_id": "TR51G_HUMAN", "id": "A0A3B3IT33-1", "name": "Tripartite motif-containing protein 51G", "aln": "----------------------------------------------MNSGILQVFQRELICPICMNYFIDPVTIDCGHSFCRPCFYLNWQDMAVLAQCSKCKKTTRQRNLKTNICLKNMASIARKASLR---QFLSSEEQICGTHRETKEMFCEVDKSLLCLLCSNSQEHRNHRHCPTEWAAEERR-EELLRKMQSLWRKMCENHRNLNMATNRIRCWKDYVSLRIE-AIRAEYHKMVAFFHEEEQRHLERLQKEGEDIFQQLNESKARMEHSRELLRGMYEDLRQMCHKAVVELFQSFGDILQRYESLLLQV-SEPVNPEFSAGPIIGLMDRLKGFR---------VYLTLQ-HARASSHIFLHGDLRSMKVGCDPQHDPNITDKSECFLQWGADFFISGKFYWEFNMGHSWNWAFGVCNNYWKEKRQNDMID------------GEVGLFLLGCVKEDTHCSLFTTSPLVMQYVPRPTDTVGLFLDCEGRTVSFVDVDRSSLIYTIPNCSFSPPLWPIICCSHF------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9BSJ1-1", "uniprot_id": "TRI51_HUMAN", "id": "Q9BSJ1-1", "name": "Tripartite motif-containing protein 51", "aln": "----------------------------------------------MNSGILQVFQRALTCPICMNYFLDPVTIDCGHSFCRPCLYLNWQDTAVLAQCSECKKTTRQRNLNTDICLKNMAFIARKASLR---QFLSSEEQICGMHRETKKMFCEVDKSLLCLPCSNSQEHRNHIHCPIEWAAEERR-EELLKKMQSLWEKACENLRNLNMETTRTRCWKDYVSLRIE-AIRAEYQKMPAFLHEEEQHHLERLRKEGEDIFQQLNESKARMEHSRELLRGMYEDLKQMCHKADVELLQAFGDILHRYESLLLQV-SEPVNPELSAGPITGLLDSLSGFR---------VDFTLQ-PERANSHIFLCGDLRSMNVGCDPQDDPDITGKSECFLVWGAQAFTSGKYYWEVHMGDSWNWAFGVCNNYWKEKRQNDKID------------GEEGLFLLGCVKEDTHCSLFTTSPLVVQYVPRPTSTVGLFLDCEGRTVSFVDVDQSSLIYTIPNCSFSPPLRPIFCCSHF------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CI25-1", "uniprot_id": "TRI49_HUMAN", "id": "P0CI25-1", "name": "Tripartite motif-containing protein 49", "aln": "----------------------------------------------MNSGILQVFQGELICPLCMNYFIDPVTIDCGHSFCRPCFYLNWQDIPFLVQCSECTKSTEQINLKTNIHLKKMASLARKVSLW---LFLSSEEQMCGTHRETKKIFCEVDRSLLCLLCSSSQEHRYHRHRPIEWAAEEHR-EKLLQKMQSLWEKACENHRNLNVETTRTRCWKDYVNLRLE-AIRAEYQKMPAFHHEEEKHNLEMLKKKGKEIFHRLHLSKAKMAHRMEILRGMYEELNEMCHKPDVELLQAFGDILHRSESVLLHM-PQPLNPELSAGPITGLRDRLNQFR---------VHITLH-HEEANNDIFLYEILRSMCIGCDHQDVPYFTATPRSFLAWGVQTFTSGKYYWEVHVGDSWNWAFGVCNMYRKEKNQNEKID------------GKAGLFLLGCVKNDIQCSLFTTSPLMLQYIPKPTSRVGLFLDCEAKTVSFVDVNQSSLIYTIPNCSFSPPLRPIFCCIHF------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P0CI26-1", "uniprot_id": "TR49C_HUMAN", "id": "P0CI26-1", "name": "Tripartite motif-containing protein 49C", "aln": "----------------------------------------------MNSGILQVFQGELICPLCMNYFIDPVTIDCGHSFCRPCFYLNWQDIPFLVQCSECTKSTEQINLKTNIHLKKMASLARKVSLW---LFLSSEEQMCGTHRETKKIFCEVDRSLLCLLCSSSQEHRYHRHRPIEWAAEEHR-EKLLQKMQSLWEKACENHRNLNVETTRTRCWKDYVNLRLE-AIRAEYQKMPAFHHEEEKHNLEMLKKKGKEIFHRLHLSKAKMAHRMEILRGMYEELNEMCHKPDVELLQAFGDILHRSESVLLHM-PQPLNPELSAGPITGLRDRLNQFR---------VHITLH-HEEANSDIFLYEILRSMCIGCDHQDVPYFTATPRSFLAWGVQTFTSGKYYWEVHVGDSWNWAFGVCNMYRKEKNQNEKID------------GKEGLFLLGCIKNDIQCSLFTTSPLMLQYIPKPTSRVGLFLDCEAKTVSFVDVNQSSLIYTIPNCSFSPPLRPIFCCIHF------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NDI0-1", "uniprot_id": "TR49B_HUMAN", "id": "A6NDI0-1", "name": "Putative tripartite motif-containing protein 49B", "aln": "----------------------------------------------MNSGILQVFQRELICPICMNYFIDPVTIDCGHSFCRPCFYLNWKDSPFLVQCSECTKSTGQINLKTNIHFKKMASLARKVSLW---LFLSSEEQMCGTHRETKKMFCEVDRSLLCLLCSSSQEHRDHRHCPIESAAEEHQ-EKLLQKMQSLWEKACENHRNLNVETTRTRCWKDYVNLRLE-AIRAEYQKMPAFHHEEEKHNLEMLKKKGKDIFHRLHLSKAKMAHRREILRGMYEELNEMCHKPDVELLQAFGDILHRSESVLLHM-PQPLNPELSAGPITGLRDRLNQFR---------VHITLH-HEEANSDIFLCEILRSMCIGCDHQDVPYFTATPRSFLAWGAQTFTSGKYYWEVHVGDSWNWAFGVCNMYWKEKNQNEKID------------GEDGLFLLGCVKNDIQRSLFTTSPLLLQYIPRPTSRVGLFLDCEAKTVSFVDVNQSSLIYTIPNCSFSPPLRPIFCCIHF------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "C9J1S8-1", "uniprot_id": "TR49D_HUMAN", "id": "C9J1S8-1", "name": "Tripartite motif-containing protein 49D", "aln": "----------------------------------------------MNSGISQVFQRELTCPICLNYFIDPVTIDCGHSFCRPCFYLNWQDIPILTQCFECLKTTQQRNLKTNIRLKKMASRARKASLW---LFLSSEEQMCGTHRETKKIFCEVDRSLLCLLCSSSLEHRYHRHCPAEWAAEEHR-EKLLKKMQSLWEKVCENQRNLNVETTRISHWKDYVNVRLE-AIRAEYQKMPAFHHEEEKHNLEMLKKKGKDIFHRLHLSKAKMAHRREILRGTYAELMKMCHKPDVELLQAFGDILHRSESVLLHM-PQPLNLELRAGPITGLRDRLNQFR---------VDITLP-HNEANSHIFRRGDLRSICIGCDRQNAPHITATPTSFLAWGAQTFTSGKYYWEVHVGDSWNWAFGVCNKYWKGTNQNGNIH------------GEEGLFSLGCVKNDIQCSLFTTSPLTLQYVPRPTNHVGLFLDCEARTVSFVDVNQSSPIHTIPNCSFSPPLRPIFCCVHL------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NI03-1", "uniprot_id": "TR64B_HUMAN", "id": "A6NI03-1", "name": "Tripartite motif-containing protein 64B", "aln": "----------------------------------------------MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKTSEKPNFNTNLVLKKLSSLARQTRPQ---NINSSD-NICVLHEETKELFCEADKRLLCGPCSESPEHMAHSHSPIGWAAEECR-EKLIKEMDYLWEINQETRNNLNQETSTFHSLKDYVSVRKR-IITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCHMPDVVLLQDVRNVSARTDLAQMQK-PQPVNPELTSWCITGVLDMLNNFR---------VDSALS-TEMIPCYISLSEDVRYVIFGDDHLSAPTDPQGVDSFAVWGAQAFTSGKHYWEVDVTLSSNWILGVCRDS-RTADANFVID------------SDERFFLISS-KRSNHYSLSTNSPPLIQYVQRPLGRVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFFCFGCT------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NGJ6-1", "uniprot_id": "TRI64_HUMAN", "id": "A6NGJ6-1", "name": "Tripartite motif-containing protein 64", "aln": "----------------------------------------------MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKISEKPNFNTNVVLKKLSSLARQTRPQ---NINSSD-NICVLHEETKELFCEADKRLLCGPCSESPEHMAHSHSPIGWAAEECR-EKLIKEMDYLWEINQETRNNLNQETRTFHSLKDYVSVRKR-IITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCHVPDVELLQDVRNVSARTDLAQMQK-PQPVNPELTSWCITGVLDMLNNFR---------VDSALS-TEMIPCYISLSEDVRYVIFGDDHLSAPTDPQGVDSFAVWGAQAFTSGKHYWEVDVTLSSNWILGVCQDS-RTADANFVID------------SDERFFLISS-KRSNHYSLSTNSPPLIQYVQRPLGQVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFFCFGCT------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6NLI5-1", "uniprot_id": "TR64C_HUMAN", "id": "A6NLI5-1", "name": "Tripartite motif-containing protein 64C", "aln": "----------------------------------------------MDSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEGRAPMRCPLCRKISEKPNFNTNVALKKLASLARQTRPQ---NINSSD-NICVLHEETKELFCEADKRLLCGPCSESPEHMAHSHSPIGWAAEECRVQKLIKEMDYLWKINQETQNNLNQETSKFCSLVDYVSLRKV-IITIQYQKMHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELWETYHMPDVELLQDVGNISARTDLAQMPK-PQPVNPELTSWCITGVLDMLNNFR---------VDNALS-TEMTPCYISLSEDVRRVIFGDDHRSAPMDPQGVESFAVWCAQAFTSGKHYWEVDVTHSSNWILGVCRDS-RTADTNIVID------------SDKTFFSISS-KTSNHYSLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFFCFGCT------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I1YAP6-1", "uniprot_id": "TRI77_HUMAN", "id": "I1YAP6-1", "name": "Tripartite motif-containing protein 77", "aln": "----------------------------------------------MASAITQCSTSELTCSICTDYLTDPVTICCGHRFCSPCLCLLWEDTLTPNCCPVCREISQQMYFKRIIFAEKQVIPTRESVPC---QLSSSAMLICRRHQEIKNLICETDRSLLCFLCSQSPRHATHKHYMTREADEYYR-KKLLIQMKSIWKKKQKNQRNLNRETNIIGTWEVFINLRSM-MISAEYPKVCQYLREEEQKHVESLAREGRIIFQQLKRSQTRMAKMGILLREMYEKLKEMSCKADVNLPQDLGDVMKRNEFLRLAM-PQPVNPQLSAWTITGVSERLNFFR---------VYITLD-RKICSNHKLLFEDLRHLQCSLDDTDMSCNPTSTQYTSSWGAQILSSGKHYWEVDVKDSCNWVIGLCREAWTKRN-DMRLD------------SEG-IFLLLCLKVDDHFSLFSTSPLLPHYIPRPQGWLGVFLDYECGIVSFVNVAQSSLICSFLSRIFYFPLRPFICHGSK------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZLN6-1", "uniprot_id": "D3ZLN6_RAT", "id": "D3ZLN6-1", "name": "", "aln": "----------------------------------------------MESDNLQASQEILTCFICLGIFTDLVLTRCGHPFCRACLLLFSADTQIPIHCPLCRHPS-KPNFRTAIPGKKLISIVRKERIK---KYLSSEEHKCMTHKERKTIFCDENRVLLCQLCSKSQEHRGHRHCHIEEAVLKQM-EKLLKQMESLLKKIQELQENLEAEKTMTDQWMDYVTLREE-MIRTEYRKLYPSLDEEEAQHIECMKNQGNTNLEELRKSEAMMVHKRSQLMKVYQELMTMSQKPYEVLQQGLDDLFRRCELVQLGM-PQVMKPELSAHPNAGLTARFSFFK---------VKIFFQNLIILNCKMSQFFDIRRFTSRPCHQNTSLDSAGS-YRASWGAMDFTTGKHYWELDLKDCEHWAVGVCSNVWLSRS-HKKIG------------SSG-AFLLVCVKEGNHYSLFTTCPVSHHYIEKPTGRVGVFLDCEGGCMSFLDVAKSSLIHSYHPEAFSLRVRPFFSTVYTRS----------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C006-1", "uniprot_id": "TRI35_MOUSE", "id": "Q8C006-1", "name": "E3 ubiquitin-protein ligase TRIM35", "aln": "----------------------------------------MEPGPSVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRRCVSGCWEVQTTPS-CPVCKERAVPGELRTNHTLNNLVETLLREEAEGARWTGRRSPRPCRAHRAPLTLFCLEDKELLCCACQADARHQEHRVQPIKDTAQDFR--AKCKNMEHVLREKAKAFWALRRTYEAIAKHNEVQTTWLEGRIRDEFDKLRDFLRVEEQATLDAMKEESRKKHLQAEEKMKQLAEQTEALAREIERLQMEMKEDDMTFLMKHKSRKRR--LFCTVE-PAPLQPGLLMDACKYLESLQYRVWKKMLGSVESVPFSLD-PNTAAGWLKVADDLTSVINHGYRVQVENPERFSSAPCLLGSQVFSKGSHSWEVDVGGLPTWRVGVVRVQAHAQAQAQADVGGEGHSHSCYHDTRSGFWYLCRTQGVDGDHCMTSDTATAPLVQAMPRRLRVELECEEGELSFYDSERHCHLYTFH--AHFGEVRPYFYLGASRGDGPPEPLRICHLRVSIKEELDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PZV1-1", "uniprot_id": "A0A8M1PZV1_DANRE", "id": "A0A8M1PZV1-1", "name": "", "aln": "MTLWRKELLSYAFSEVKVKGRNESVGYSVGFTVSSTVECLHWGLFTVMADALSFLEEDLSCLICCDVFTDPVTLKCSHSLCENCLKSFWK-TQDVLQCPVCRKECSPDEPTKSLAFRALCESFKTRKPT------AVSGDVCPQHKETLKLFCFEDKQPICVVCYTSKKHENHKCSPVEEAAGNLK-----ADLKMQMDKLQVTLDDLKKTHESCMEQAENIMEKEEIQIKKEFEKLHQFLKDEEDKWIKALKKQIKPQDGKFKARIKHLSTQITDLSERMAALWQDMEAENIPFLQNYSDTLQKLKHSSVEKRPAEAEKYQHHSPQTMIFTTWARMQN-----LVEQPPVILDPNTASSKQWVSADCTSVQYVLKKVH-MCDNPKRLFLGVLASQGFNSGLHCWDVEVRDNNHWTLGVVGETVYRKRLYRMDP----------------KSRFWCFRFVDGKFKKGNNPGKAIDENKRPNIIRVQLDFEKGELRFIDPFRNKNLCTFTG-GFPERVFPYFCSGDLATPLNIFPANKEKF----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * * :* . : * * * * :* *. * * . . * *. ::* :: :* * . .* * : .: * * :: *: ** :. : .: . . . : : * : . : . : : . : : * . *:..: * .*: : : . . : : *: : : * : : : : * : ", "identical_positions": 31, "similar_positions": 63, "identity": "5.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110921-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VDV3-1", "uniprot_id": "R3GEF_MOUSE", "id": "Q8VDV3-1", "name": "Guanine nucleotide exchange factor for Rab-3A", "aln": "---------------------MWSGQPQQD--EGLPVGLSAIPVP-----------------WKNLGPSKSNRESSGGLV----EASTSWEEAQG----EEHPAPAPLD------VSRLRSS--SMEIREK-------GSEFLKEELYKAQKELKLKDEECERLCKVRAQLEQELEELTASLFEEAHKMVREANMKQATSEKQLK---------------EAWGKIDMLQAEVTALKTLVITSTPASPNRELHPQLLSP--TKAGPR-KGHSRQKSTSSSLCPVVCPTA-----------GHIPTPDKEGKEVDTTLFAEFQAWRASPTLDKSCPFLERVYREDVGPCLDFTVQELS-------------ALVRTAVEDNTLTIEPVASQTLPAVKVPTVECNN------TNTCALSGLARTCHHRIRLGDSDS-------HYYISPSSRARITAVCNFFTYIRYIQQGLVRQDAEPMFWEIMRLRKGMSLAKLGFFPQEA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99NH3-1", "uniprot_id": "R3GEF_RAT", "id": "Q99NH3-1", "name": "Guanine nucleotide exchange factor for Rab-3A", "aln": "---------------------MWSGPPQQD--EGLPVGLSAISVP-----------------WKNLGPSKGNRKSPGGLV----EASASWEEAGG----EEHPAAAPLD------VSRLRSS--SMEIREK-------GSEFLKEELYKAQKELKLKDEECERLCKVRAQLEQELEELTASLFEEAHKMVREANMKQAASEKQLK---------------EAWGKIDMLQAEVTALKTLVITSTPASPNRELHPQLLSP--TKAGPR-KGHSRQKSTSS-LCPVVCPTA-----------GHIPTPDKEGKEVDTTLFAEFQAWRASPTLDKNCPFLERVYREDVGPCLDFTVQELS-------------ALVRTAVEDNTLTIEPVASQTLP-----NVECNN------TNTCALSGLARTCHHRIRLGDSDG-------HYYISPSSRARITAVCNFFTYVRYIQQGLVRQDAEPMFWEIMRLRKGMSLAKLGFFPQEA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TBN0-1", "uniprot_id": "R3GEF_HUMAN", "id": "Q8TBN0-1", "name": "Guanine nucleotide exchange factor for Rab-3A", "aln": "---------------------MWSGPPQPD--QGLPPPLAAVPVP-----------------WKSTDPCQGHRESPGALV----ETSAG-EEAQG----QEGPAAAQLD------VLRLRSS--SMEIREK-------GSEFLKEELHRAQKELKLKDEECERLSKVREQLEQELEELTASLFEEAHKMVREANMKQAASEKQLK---------------EARGKIDMLQAEVTALKTLVITSTPASPNRELHPQLLSP--TKAGPR-KGHSRHKSTSSTLCPAVCPAA-----------GHTLTPDREGKEVDTILFAEFQAWRESPTLDKTCPFLERVYREDVGPCLDFTMQELS-------------VLVRAAVEDNTLTIEPVASQTLPTVKVAEVDCSS------TNTCALSGLTRTCRHRIRLGDSKS-------HYYISPSSRARITAVCNFFTYIRYIQQGLVRQDAEPMFWEIMRLRKEMSLAKLGFFPQEA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PH17-1", "uniprot_id": "A0A8M9PH17_DANRE", "id": "A0A8M9PH17-1", "name": "", "aln": "----------MDAFEGLHQVQLSSSPPTAPGYEVLLTRHSGIAVYSSPVFFSRGEIAEHHHHHHHHHTAEEERCPVGRLVDLEPEPSPRLEGDDGGRREKKPPDEAGADRREAYNMSRLRSS--SLEIKEK-------GTEFLREQLDAAQKELKLKDEECERLSHVRNQLEQELEELTASLFEEAHKMVREANVKQAAAEKQLK---------------EAQGKIDVLQAEVSALKTLVLTSTPSSPNRQLHPQLLSPGSSRASSRPFGHTRNKSASGALQTEPTNPE-----------KDTVHHDR---ELDSVLFAEFLSWKECPNLERSSAFISRVYREDIGPCLSFTSAELS-------------QSVQRCVENNSLTIEPVITSSLPTDKNIHQGGTNGCWTPIETKCALSGLTRPCRHRIKLGDKEN-------YYYISLSSRARITAVCNFFTYIRYIQQGLVRQDVQQMFWEVMRLRREMSVAKLGFFHTEHS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P17065-1", "uniprot_id": "SEC2_YEAST", "id": "P17065-1", "name": "Rab guanine nucleotide exchange factor SEC2", "aln": "MDASEEAKRVSIQVTSLSTQLIESVDKQSHLEEQLNKSLKTIASQKAAIENYNQLKEDYNTLKRELSDRDDEVKRLREDIAKENELRTKAEEEADKLNKEVEDLTASLFDEANNMVADARKEKYAIEILNKRLTEQLREKDTLLDTLTLQLKNLKKVMHSLDNESTVTNNSNRYSTILSDSATSSSTSLNKVPTSYSLASQDIYSGIVYSPSISSIRYDISLYNEFLKFVAALPRCENIKATSTESKLIRRLVNDEIQPILKIDNASGIGWLVKKTLLSLIIDGLVVVEPLSGVNATYQIGYNSSSPAKQATSNMPKMFKFPLDSPPVAVHAACSFCGESRDDIIEHARMYILKTLHKTDDGKEQVTNTYPLCHWCLLKLRQTCEIFAFLRSLKVGAWHLEKLTTQNITKEDLEKFSEVTKHTKRDGRVSSQDKKTKRLSFMAGLGINSSTKNKPKMEIFSSETNAKPGQPTTNIQRAWLQLCKLRCILHWTHIGIWAVDDSISSKIGPLVEDDSDEDQNDAISVRLQDKALWKQDAKRPFSSSSAEESQKSDAFDFESGDMENEITGESSSDESSSDGSSTDNSTADSSSEDESSLADSTTSSADSSSPESIDNGEGDDTVTKDDKSSIKSANNNEENSDCGDKKGRSIIKKKAPQRKIQKKKLLQDLDDLEEQFREESAIDQTEFENAESNVKQNISSKRASSGDENSKKDNNEKTLKTNLTIGDKTQEQIGENSPSSGLHASSSNDDNFDDAQEQQ", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : * :. : . . : * . * . : * : *.. ::** :* .: * : * *:** .. :. . * : :: *: * ..: .: : .. . :::. . . .:: : * :. :.: *** :. *.* : :.* . .. * :*: . : : : :* :. ..* . : : . : * : .: . * * . . :* ::: :: ::.... :. .* :: .. ::*: : * : : : :: :** : :::*:: : ", "identical_positions": 38, "similar_positions": 121, "identity": "5.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110922-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5SWY8-1", "uniprot_id": "SC5AA_MOUSE", "id": "Q5SWY8-1", "name": "Sodium/mannose cotransporter SLC5A10", "aln": "MAGNSTGDAHVPGSQLSVTDIIVISVYFALNVAVGIWSACRANKNTVSGYFLAGRDMAWWPIGASLFASSEGSGLFVGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRFGGQRIRTYLSVLSLMLSVFTKISIDLYAGALFVHICLGWNFYLSTILTLAITALYTIAGGLATVIYTDALQTIIMVVGAVILAVKAFNQIGGYEQLEAAYAQAIPSRTIPNTTCHLPRADAMHMFRDPSTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARNLNHAKAGSILASYLKMLPMGLMIMPGMISRVLFPDDVGCVVPSECLRACGAEIGCSNIAYPKLVMELMPIGLRGLMIAVMMAALLSSLTSIFNSSSTLFTMDIWRQLRPSAGERELLLVGRLVIVVLIGVSVAWIPVLQGSNSGQLFIYMQSVTSSLAPPVTAIFILGIFWRRANEQGAFWGLMAGLVVGALRLVLEFLYPEPPCGQIDTRPAPLRSLHYLHFAIALFLLTCAVMAAGSLLSPPPQQRQIENLTWWTLA---------PNWSLGTKTGDGQTPQKR--------------------------------AFWARVCNVNAIFLMCVNIFFYAYFA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0PJK1-1", "uniprot_id": "SC5AA_HUMAN", "id": "A0PJK1-1", "name": "Sodium/mannose cotransporter SLC5A10", "aln": "MAANSTSDLHTPGTQLSVADIIVITVYFALNVAVGIWSSCRASRNTVNGYFLAGRDMTWWPIGASLFASSEGSGLFIGLAGSGAAGGLAVAGFEWNATYVLLALAWVFVPIYISSEIVTLPEYIQKRYGGQRIRMYLSVLSLLLSVFTKISLDLYAGALFVHICLGWNFYLSTILTLGITALYTIAGGLAAVIYTDALQTLIMVVGAVILTIKAFDQIGGYGQLEAAYAQAIPSRTIANTTCHLPRTDAMHMFRDPHTGDLPWTGMTFGLTIMATWYWCTDQVIVQRSLSARDLNHAKAGSILASYLKMLPMGLIIMPGMISRALFPDDVGCVVPSECLRACGAEVGCSNIAYPKLVMELMPIGLRGLMIAVMLAALMSSLTSIFNSSSTLFTMDIWRRLRPRSGERELLLVGRLVIVALIGVSVAWIPVLQDSNSGQLFIYMQSVTSSLAPPVTAVFVLGVFWRRANEQGAFWGLIAGLVVGATRLVLEFLNPAPPCGEPDTRPAVLGSIHYLHFAVALFALSGAVVVAGSLLTPPPQSVQIENLTWWTLA---------QDVPLGTKAGDGQTPQKH--------------------------------AFWARVCGFNAILLMCVNIFFYAYFA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B626-1", "uniprot_id": "A0ACD6B626_DANRE", "id": "A0ACD6B626-1", "name": "Sodium/mannose cotransporter SLC5A10", "aln": "MAFNSTTKFFALSQSFSVSDIIVIGAYFLLNVAVGIWSSCRVSRNTLSGYFLAGRDMAWWPIGASLFASSEGSGLFIGLAGTGAAGGIAVAGFEWNATYALLALAWVFVPVYVSSGIVTMPEYLGRRFGGERIRMYLSALSLLLSVFTKISTDLYSGALFVQVCLGWNLYLSTVLMLVVTALYTIAGGLAAVIYTDTLQTFIMIIGAVILTITAFNKIGGYSNLESVYLQAVPSKIIPNTTCHLPRHDAMHLFRDPVHGDLPWPGMTLGLTIIATWYWCTDQVIVQRSLSAKSLSHAKGASIFASYLKLLPMMFIILPGMISRALYPDTVACVDPEECVKVCGAEVGCSNIAFPKLVIELMPSGLRGLMIAVMMAALMSSLTSIFNSSSTLFTMDIWKKYRRGASEKELLLVGRIVTVILVVISVVWIPILQSANSGQLYVYIQSVTSYLAPPVTAIFVMAVFWKRTNEAGAFWGLMVGLVVGLTRMVLEFAFPPPRCGVFDPAPSVLRSMHYLHFAIILCALTAIVVAVISLLTPPPTEEQTRNLTWWNLHNSTEREIPLQKVSTLSRRTDGCESVRRGKCVRTAGFCSPRPGRFASGTPPPIIHSTTEDPFWSRFCCVNAIILMCVNIFLYAYYA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *** . .. . .:**:***** .** *********:**..:**:.*********:******************:****:*****:***********.**********:*:** ***:***: :*:**:*** ***.***:******** ***:*****::*****:****:* * :***********:*****:***:**::*****::.**::**** :**:.* **:**: *.******** ****:**** *****.***:****:******************:.*.***..**:*****:*** ::*:******.*:** *.** *.**::.****:******:****:**** **********:***:*******************:: * :.*:*******:* * *: :**.***:**.:*****::*:***** *******:*::.:**:*:** ******:.***** *:**** * * ** *. *: * *:******: * *: *:.. ***:*** . * .*****.* . . :: ** . :: .**:*.* .***:*******:***:*", "identical_positions": 407, "similar_positions": 127, "identity": "63.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110922-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5SWY7-1", "uniprot_id": "FA83G_MOUSE", "id": "Q5SWY7-1", "name": "Protein FAM83G", "aln": "MAFSQVQCLDDNHVNWRSSESKPEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLSELELSRIVEAIEVYDPGSEDPRVSGRRPEPQDNGGADASEETSAAGGPPATETLPSLEYWPQKSDRSIPQLDLGWPDTIAYRGVTRASVYMQPPIDGQPHIKEVVRKMVSQAQKVIAVVMDMFTDVDIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERARMHLGHLKNLRVRSSGGTEFFTRSATKFKGVLAQKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQFQELYLMSQSVSLKDIPMEKEPEPEPIVLPSVVPLVPTGTMAKKLVNPKYALVKAKSVDEIAKSSSDKQEVTRPPGLRGPAVAERPGDLSELLPPVHPGLLNLERANMFEYLPTWVEPDPEPGSDILGYINIIDPNIWNPQPNQMNRIKIRDTAHASAQHQLWKQSQGARPCPAPCPPPAPRDSQGVVPAENGFP---------------QGNPEPQAPVPKPRTVPVASVLARDGSD----------------------------IGWALDTPEKETPQNGIDPRLPSTASESEVPQQQHSSMTQDDPDGLERGLPNGLD-EDEDDD---DDYVTLSDQDSLSGSSGPGPGHRRPS----VASSMSDEYFEVRERSVPLQRRHSEQMANGPGHPPRRQLSAPHVTRGTFGGPLSSPLWAQGRSRE----------------------DVDAS-RIQGQRPMDRQAQGQHFHRHGSTTSRT------PGPPRFR-------------------PAADGTQSSSKKASPAAAGP-------------------------------HHWQPKGSPTPRMLPDPGSPRPTRNTRLRAELRATEEHASPFGIPYSKLSQSKHLKARAGGSQWAPSDSKRRA---RDHKEP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6ND36-1", "uniprot_id": "FA83G_HUMAN", "id": "A6ND36-1", "name": "Protein FAM83G", "aln": "MAFSQVQCLDDNHVNWRSSESKPEFFYSEEQRLALEALVARGRDAFYEVLKRENIRDFLSELELKRILETIEVYDPGSEDPRGTGPSQGPEDNGVGDGEEASGADGVPIEAEPLPSLEYWPQKSDRSIPQLDLGWPDTIAYRGVTRASVYMQPPIDGQAHIKEVVRKMISQAQKVIAVVMDMFTDVDIFKDLLDAGFKRKVAVYIIVDESNVKYFLHMCERACMHLGHLKNLRVRSSGGTEFFTRSATKFKGALAQKFMFVDGDRAVCGSYSFTWSAARTDRNVISVLSGQVVEMFDRQFQELYLMSHSVSLKGIPMEKEPEPEPIVLPSVVPLVPAGTVAKKLVNPKYALVKAKSVDEIAKISSEKQEAKKPLGLKGPALAEHPGELPELLPPIHPGLLHLERANMFEYLPTWVEPDPEPGSDILGYINIIDPNIWNPQPSQMNRIKIRDTSQASAQHQLWKQSQDSRPRPEPCPPPEPSAPQDGVPAENGLP---------------QGDPEPLPPVPKPRTVPVADVLARDSSD----------------------------IGWVLELPKEEAPQNGTDHRLPRMAGPGHAPLQRQLSVTQDDPESLGVGLPNGLDGVEEEDD---DDYVTLSDQDSHSGSSGRGPGPRRPS----VASSVSEEYFEVREHSVPLRRRHSEQVANGPTPPPRRQLSAPHITRGTFVGPQGGSPWAQSRGRE----------------------EADALKRMQAQRSTDKEAQGQQFHHHRVPASGTRDKDGFPGPPRYR-------------------SAADSVQSSTRNAGPAMAGP-------------------------------HHWQAKGGQVPRLLPDPGSPRLAQNARPMTDGRATEEHPSPFGIPYSKLSQSKHLKARTGGSQWASSDSKRRAQAPRDRKDP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F4B5-1", "uniprot_id": "E7F4B5_DANRE", "id": "E7F4B5-1", "name": "", "aln": "MALSQVQCLDDNHINARTNESKPEFLYSEGQRLALETLIHAGRDAFEDYIKTNSIRCFLSDLELERIFGTAEVYSPGS-------PQNNAEVYWEGDGEEIS--------------LQYWPDRSDRSIPQLDIGWPDRASYRGVTRVQVYTQPPYEGQSHIKGVVRKMIGQAQKVIAVVMDLFTDIDIFKDLLDASYRRKVAVYIMLEATGVKHFMRMCEKAGMHTGHLKNLRVRSIRGAEFLSRSSKRVYGSQSQKFMFIDGDKAVSGSYSFTWSASRLDRNLITVLTGQAVDTFDTLFQDMYMLSNGVCLSKINLSSEPEPE-YVPQAVPTPLPSATKALKLINPKYTLVSNCAFTTNGPVSDQTSAQNSTSKNQTEVVKVTP-----VVPPVHPGLLNLEKADMINYIPTWPDPDPP--SDVIGFINIRDAN--KPLQAHLMRSELFEVSQAIRFKDPVHEPVESSFLRASPGPVSQTSSHPEVPAQKQTPGEAQMDFDKNQHQTSNQSENLVLPLEKPKMMHVLAFNKVDKEEPCVSEKDLDTKSLQSKNICTKKDFAKAISSFQDDTVSDTKGIQDTLQPLNCSNHTSEELYWKSSAVSNKSDLVESFAIPKSPSVKQSQDDQIITDVVTQNHIETKPETNQNGWNGTKMSNCDSSMSSLSDEYYECFSPVADFRSVEDIFVPEETRESLPNPIKKGHQGQAILRSKSCPAQDCEDLGNSQNYFTPKLLKTSCSIIFNFLSAECKTTAALSKTTFAQENDKGAIINDSKQPVKDSESCCFLQTPNGYLNFSLTSDEYFECSDTVGLKSEIDCVVSKELSSAENINEPQRITKLILEAEKLPELGCQNIKEKVEPEMHSGQEQPEFQHVLHMTADSNLPDGSRAVLLSEDNTQAQSNDKLLKQVQDSEVTSKPAVDTESMSSVLQQHMARASQQFLERQTKAVSVELTEKMSIQDLQIESLQEVLPHASQNINSKDKFVLFDKRNSNPEFESEVSVDVVCEEHFVKSLQDLQPELSSDLIPKPPEVNKVADKMAMQDLQLKASLNLMCEGSKKESVQGLQPNASLDLIGEVKPLWSSKKNSESGFVSEVSVDLVCEEQSVQTLQDLHPGSSSDLQLKTSEVNVCVEKSEKKAMQDLQLEEGLDLVCEESEKESLQGLQPDTSLGLTGKENPLLLAKKISNPNLECEVNRDVACEEKSVKSLQDLQPEPSSNLLLKPTEVNVSVEVAENNAMQDLQLKVSLEESEKESPQGLQPTAITLIDEEKPLLLAMKHSDSGFLSEVSVDVVCEEHSVKPLQDLQPEVSLDLMLKPAEGNVILHYATDSVFNCSILQDKADVTSVIPEKPEITKLIELPKIKELQKSLTCLDCSSKHQHNLRSEEDVNEHLRLPNDEVSQAVLKIKSEQHNSQMKIPEQFESIELLILEDSDLQMTEQDQSDPGSPIVALSKETKICKTKPIQMKTTIDRKLTEEKLGHEVYSRNGKETCYPTAPDEEKQEGEHICTNQTYKNLPEAKPKMESLARKHSLQTSSRIPIQARRGSTKLPIGKLDTSNCSSGLQAPKCGIHKQLPGKPMGQKKTSITPPSSPEKPSIGKITPVRPTQIPQRPTWTVPTPNSPTSPTNQNQQTAPRIKPPDQPNVSRSASMTKYSRSSYEISCTRQVKKQAVKGILPSP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:**********:* *:.******:*** ******:*: ***** : :* :.** ***:***.**. : ***.*** .: .*..* : *:***::*********:**** :******..** *** :**.*** *****:.***********:***:*********.::*******::: :.**:*::***:* ** ********** *:**::**:.:. * :*****:***:**.*********:* ***:*:**:**.*: ** **::*::*:.*.*. * :..***** * :* . :*:.* * **:****:**. :. . *.:.. . . : .: * ::**:*****:**:*:*::*:*** :*** **::*:*** *.* :* :: * :: :.::* :: ::. : . * .: ***:: * : . : *: **: : * . * .: .: : .. :. * .. : ::::.. .:*:. . :.:** * ** .. :: . :. * . : * **:*:**:* . . :: .. :.: . . . :. * :. : . . .:. ... : .: :. :.: :* :: ... : * : . * . *. .:. * : *.: . :: .*.. * :: . : ::.: . : .. ** . *. .. * : ::: ", "identical_positions": 272, "similar_positions": 250, "identity": "16.26%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110927-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2K2D4-1", "uniprot_id": "A0A0G2K2D4_RAT", "id": "A0A0G2K2D4-1", "name": "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3", "aln": "------------------------MNFQAGGG--------QSPQQQQSLAAPGGGGSGGGGAGGGGQFGGAGPGAGGGGPSQ--------------------------------------------------------------------------------------------------------------QLAGGPPQQFALSNSAAI--------------RAEIQRFESVHPNIYAIYDLIER-------------------------------------------------------------------------------------------------------------------------------------------------------IEDLALQNQIREHVISI---------------------------------------------------------------------------EDSFVNSQEWTLSRSVPELKVGIVGNLSSGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPELQFAAWVDAVVFVFSLEDEISFQTVYNYFLRLCSFRNASEVPMVLVGTQDAISAANPRVIDDSRARKLSTDLKRCTYYETCATYGLNVERVFQDVAQKVVALRKKQQLAIGPCKSLP-----------NSPSHSAVSAASIP---AVHINQATNGGGSAFSDYSSSVPSTPSIS---------------QRELR----------IETIAASSTPTPIRKQSKRRSNIFTSRKGADPDREKKAAECKVDSIGSGRAIPIKQGILLKRSGKSLNKEWKKKYVTLCDNGLLTYHPSLHDYMQNIHGKEIDLLRTTVKVPGKRL--PRATPSTAPGTSPRGANGLALERSNTQLG-GTTGRPHSAS---SASLHSERPHR-SAWAGSRP--EGLHQRSCSISSTDQWSAAAA---LPASVQRPASGPAELLSS-SPKLEPPPSPRSNRKKQRRKKSTGTPRPDGPNSAAEETEESFEFVVVSLTGQTWHFEASTAEERELWVQSVQAQILASLQGCRSAKDKTRLGNQSTALAVQTVRT-ARGNSFCVDCEAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDLDDWPPELLAVMTAMGNALANSVWEGALDGYSKPGPEACREEKERWIRAKYEQKLFLAPLP--SSDVP---LGQQLLRAVVEDDLRLLVMLLAHGSKEEVNETYGDGDGRTALHLSSAMANVVFTQLLIWYGVDVRSRDARGLTPLAYARRAGSQECADILIQHGCPGEGCGLA-PTPNRE---PANGTN-----------------PSAELHRSPSIL------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VHH5-1", "uniprot_id": "AGAP3_MOUSE", "id": "Q8VHH5-1", "name": "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3", "aln": "------------------------MNFQAGGG--------QSPQQQQSLAAPGGGGAAAQQLVCGGQFGGAGPGAGGGGPSQ--------------------------------------------------------------------------------------------------------------QLAGGPPQQFALSNSAAI--------------RAEIQRFESVHPNIYAIYDLIER-------------------------------------------------------------------------------------------------------------------------------------------------------IEDLALQNQIREHVISI---------------------------------------------------------------------------EDSFVNSQEWTLSRSVPELKVGIVGNLSSGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPELQFAAWVDAVVFVFSLEDEISFQTVYNYFLRLCSFRNASEVPMVLVGTQDAISAANPRVIDDSRARKLSTDLKRCTYYETCATYGLNVERVFQDVAQKVVALRKKQQLAIGPCKSLP-----------NSPSHSAVSAASIP---AVHINQATNGGSSAFSDYSSSVPSTPSIS---------------QRELR----------IETIAASSTPTPIRKQSKRRSNIFTSRKGADLDREKKAAECRVDSIGSGRAIPIKQGILLKRSGKSLNKEWKKKYVTLCDNGLLTYHPSLHDYMQNIHGKEIDLLRTTVKVPGKRL--PRATPTTAPGTSPR-ANGLAMERSNTQLG-GATGAPHSAS---STSLHSERPHS-SAWAGSRPGPEGLHQRSCSVSSTDQWSEAAA---LPASMQHPASGPAESLSS-SPKLEPPPSPHSNRKKHRGKKSTGTPRPDGPSSAAEEAEESFEFVVVSLTGQTWHFEASTAEERELWVQSVQAQILASLQGCRSAKDKTRLGNQNTALAVQAVRT-VRGNSLCIDCEAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDLDDWPPELLAVMTAMGNALANSVWEGALDGYSKPGPEACREEKERWIRAKYEQKLFLAPLP--SSDVP---LGQQLLRAVVEDDLRLLVMLLAHGSKEEVNETYGDGDGRTALHLSSAMANVVFTQLLIWYGVDVRSRDARGLTPLAYARRAGSQECADILIQHGCPGEGCGLA-PTPNRE---PANGTN-----------------PSAELHRSPSIL------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96P47-1", "uniprot_id": "AGAP3_HUMAN", "id": "Q96P47-1", "name": "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3", "aln": "------------------------MNFQAGGG--------QSPQQQQ-------------------------------------------------------------------------------------------------------------------------------------------------QLAGGPPQQFALSNSAAI--------------RAEIQRFESVHPNIYAIYDLIER-------------------------------------------------------------------------------------------------------------------------------------------------------IEDLALQNQIREHVISI---------------------------------------------------------------------------EDSFVNSQEWTLSRSVPELKVGIVGNLSSGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPELQFAAWVDAVVFVFSLEDEISFQTVYNYFLRLCSFRNASEVPMVLVGTQDAISAANPRVIDDSRARKLSTDLKRCTYYETCATYGLNVERVFQDVAQKVVALRKKQQLAIGPCKSLP-----------NSPSHSAVSAASIP---AVHINQATNGGGSAFSDYSSSVPSTPSIS---------------QRELR----------IETIAASSTPTPIRKQSKRRSNIFTSRKGADLDREKKAAECKVDSIGSGRAIPIKQGILLKRSGKSLNKEWKKKYVTLCDNGLLTYHPSLHDYMQNIHGKEIDLLRTTVKVPGKRL--PRATPATAPGTSPR-ANGLSVERSNTQLG-GGTGAPHSAS---SASLHSERPLSSSAWAGPRP--EGLHQRSCSVSSADQWSEATTS--LPPGMQHPASGPAEVLSS-SPKLDPPPSPHSNRKKHRRKKSTGTPRPDGPSSATEEAEESFEFVVVSLTGQTWHFEASTAEERELWVQSVQAQILASLQGCRSAKDKTRLGNQNAALAVQAVRT-VRGNSFCIDCDAPNPDWASLNLGALMCIECSGIHRHLGAHLSRVRSLDLDDWPPELLAVMTAMGNALANSVWEGALGGYSKPGPDACREEKERWIRAKYEQKLFLAPLP--SSDVP---LGQQLLRAVVEDDLRLLVMLLAHGSKEEVNETYGDGDGRTALHLSSAMANVVFTQLLIWYGVDVRSRDARGLTPLAYARRAGSQECADILIQHGCPGEGCGLA-PTPNRE---PANGTN-----------------PSAELHRSPSLL------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AZA0-1", "uniprot_id": "A0A8M3AZA0_DANRE", "id": "A0A8M3AZA0-1", "name": "Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3", "aln": "MGLQEEVQTLMPSGRAEKRGEDEFIAVKSNVGEEDDDNERQANQREERQESPGQRRSAAGKLNRWLYLSSTGNRGWRKGEVLGMRTDRLPILRDNCTQQSSAEHFDFAGVEKALELRTGVCHIPFKELICNAVSVENATESHVVVLQRPAHGLRLLGSRRAMSMFVFPDNNRRQQTTSTNHQDSSTRPHSFCMLEATNSKQVILPTSASTNHGFPDVVQRCRTRRAELRAIDGLKPDMPPSASLLPLRLEEPPIRRTLKSRSKPRPVSMTVLELYKERSGSRDELASHTGTGSLPRPGFRWKWFGRQATGKEMGVTQISAKLKESNKEEAPKKMFGSLRRSLSLRMRRNRNQPEHEDRTELRRTASIGEKSMQSTRPFSYLTGRTLAPACEQDEDQGATQYIQYQTQGKVAVLEVPLRPAKLTKPTKQMQPETSFWQLIASRFKRKEPLSSNKSELSTGSQAVGSHPPVRNKKPDSVAIETLAGIGFRKGQDSFVNSQEWTLSRSVPELKVGIVGNLSSGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPELQFAAWVDAVVFVFSLEDEISFQTVYNYFLRLSSYRNAAEVPMVLVGTQDAISAANPRVIDDARARKLSNDLKRSTYYETCSTYGLNVERVFQDVAQKVVALRKKQQLSIGPCKSLP-----------NSPSHSSVPAASIP---SVHINQAANGGG-AFSDYSSSVPSTPSIS---------------QREMR----------IETVAASNTPTPIRKQSKRRSNIFTSRKASD---QTKSIESKTDSIGSGRAIPIKQGILLKRSGKSLNKEWKKKYVTLCDNGLLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRP--PRAVATVAPTASPK-TNGLTKDRSTLQLGIGATSTPHSNS---SSSLQSGGSTAGVALGTNKE---GMHQRSFSVSSAEQWNEAVISTTSANGVSDPLSSASGMSSATSPKLEPPPSPHANRKKHRRKKSTGITKPDSLSAGSEEPEESFEFIIVSLTGQMWHFEASTFEERELWVQAIESQILASLQSCESSKNKSRLGSQSDALAIQSIRN-VRGNSFCADCDAPNPDWASLNLGALICIECSGMHRNLGTHLSRVRSLDLDDWPVELSMVMTAIGNAMANSVWEACVDGYNKPGVDSTREEKERWIRAKYEQKLFVVALP--QSDVP---LGQQLLRAVVEDDLRLVVLLLAHGTKEEVNETYGDGDGRTALHLSCAMANVVITQLLIWYGVDVKSRDARGQTPLSYAQRAGSQECADILIQHGCPAEGGALSTPTATRH---NPNINNNNG--------------QCAELNRSLSIM------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NGC3-1", "uniprot_id": "CEG1A_DROME", "id": "Q9NGC3-1", "name": "Centaurin-gamma-1A", "aln": "--MSNYHPHSHPHALSHPHPQQVHNQLQNPHQN------QLPPPQRHNHAAPTAAASASGAPSSSASASASAS-----------------------------------------------------------------------------------------------------------------------ILVAHPP-QPLISNSLAI--------------RQEIQRFESVHPSIYAIYELIDLLP-----------------------------------------------------------------------------------------------------------------------------------------------------MADAQIAQSIRDHVVCI---------------------------------------------------------------------------EDSFVNSQEWTISRSVPDLRLGIVGSLNSGKSALVHRYLTGSYMQEESPEGGRFKKEVFIDGQSYLLLIRDEGGAPEMQFAGWVDAVIFVFSLENEGSFNTVYNYYTKMAHFRNGQEIPMILVGTQDAISERNPRVIDDTRARKLASDLKRCSYYETCATYGLNVERVFQDACQKILSQRLPLPPQVQPARPTTPQGNRLGLAPYQAPTNGQRGQQQLPLRMSADFAQAEQKLWSLQAASSSTINENNNITKYNPGAANSLQGDCSQVQLRDPRDLAPPPGKELPTPTSTPTTSRK-SRRRSNLFIPSSSKK---ADKEKEPKSSELGSGRSIPIKQGYLYKRSSKSLNKEWKKKYVTLCDDGRLTYHPSLHDYMDDVHGKEIPLQYVTVKVPGQKPRGSKSIITNSALTSSLMANGQR-AQNTLSDGIGCLTLAKDNQRKLSEKLSLLGAGSIAAGAGGEP----LKSNSSQQTSGDEG--------IAMSNSNSQTFIAGEVANAGNKLEAQTP--NVKKRHRRMKSS------SVKANEADDNDGYEFYIVSLDSKQWHFEAANSEERDEWVAAVEQEIFKSLQSIESS--KTKQATSTDLAAMLAIRQRVPGNGFCVDCGAPNPEWASLNLGVLMCIECSGVHRNLGSHISKVRSLGLDDWPSPHLSVMLAIGNSLANSVWESNTRQRVKPTSQASREDKERWVRSKYEAKEFLTPLGNGSSAHPSPSPGQQLIEAVIRADIKSIVSILANCPSEVTNANVSARDVRTPLLLACAIGNLAIAQLLIWNGANIKHTDHEGRTCLAYARAAQSLATAKSIKAAAAAQAGTTIPAPAPPTNGGIPAPQYNVEDTTALVELLEGLGCPEAAPLTASGTLPRRRDTLGTPYEKSVSGVI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . :.. * . . * :..* : * *:: ::.::*.: . .*: . : *: : :**********:*****:*::****.*.*************:*:*************:.:**************.**:***.*****:******:* **:*****: ::. :**. *:**:********* *******:*****:.****.:*****:************..**::: * : *.:. . ::*::. .:* :..: ** : : **:: .. .*: * ::* * :.:.***. ** *:****:* . .. . * * : ..:****:****** * ***.****************:* ***********:::***** * .******:: .:: : :. :*. :** :.. . * * .:. . * .* . * . . ::..* . :* :: . . . . : : : . **:. .. :*::* **: . .: : ::.:** :*** .: *****:. ***: ** ::: :*: ***. .*: *:: .... *: ::* . **.:* ** ****:*******.*:******:**:**:*:*:****.***** ** *:**::******. ** :: **:****:*:*** * *:..* .* * ****:.**:. *:: :* :**: ..* .* . . * **.* *:.*:.*:.::***** *.::: * .* * *:**: * * *. : ... * :. *:. . . * .* * * :: ", "identical_positions": 367, "similar_positions": 260, "identity": "26.44%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110929-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VMS4-1", "uniprot_id": "Q9VMS4_DROME", "id": "Q9VMS4-1", "name": "", "aln": "MSIVCTLEQKVNFFKAAATTKNLLILKNNTDTNYINNYKQDNPSNNKFPRIQAQSNNSHLQHQQQLQQKLAQLHHYSQQKLSGSDFPYGPRPPTGGKEEKLLLLAPPGKLYPEASVSTAMPEVLSGTPTNSHNKANIAMMNNVRLSNISPTLSMNGSSNEASNLHPLSMYGGSISPQSNDSGMSDSLGKYVPGSGYGDGMMAQSPSQGGNGPQSALTAAQKELFSQRKQREFTPDNKKDESYWDRRRRNNEAAKRSREKRRYNDMVLEQRVIELTKENHVLKAQLDAIRDKFNISGENLVSVEKILASLPTSEQVLSNTKRAKMSGSGGSSSGSSPSGSGSGEGSPQGGHNGYPVGPPLSPLIYGPNG--NARPEATVKSVHHIHHAGVAPPPTHLQQLVVPQSQTQHLYQPQPQQHQPHQQQQISQPPQQQQQQQEPSPSAGSSSPVISDPHNRPPSTTIANLQVQLQQALNRNVRPEDLDSLRKVVAAGALYNAAAVVGAPPPPPSAGLYVPAPSAYKDHLEAAAAWSHNVEAAVSSSAVDAVSSSSVSGSAASVLNLSRRACSPSYEHMLSSTTSSTLSSASSSGAVSGDDEQEHEPAHMAPLQLQRSSPQQGSDANNCLPLKLRHKSHLGDKDAAATALLSLQHIKQEPNCSRASPPAWNDGGDNSSDERDSGISIASAEWTAQLQRKLLAPKEANVVTSAERDQMLKSQLERLESEVASIKMILAE", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M2BBT7-1", "uniprot_id": "A0A8M2BBT7_DANRE", "id": "A0A8M2BBT7-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MESLNLQISTNSSEN-LENTESFSDYSDLHSPQD------------IPR-------------------QSRLLKPKPNNMSCRRKREFISDEKKDASYWEKRRKNNEAAKRSREKRRFNDMILENRVLALNDENVRLKTELLQLKLRFGLISTASYMEKSQQIGSAVNRSSGSSSSSSSTTGHFYSSGYSSVSQMMLNSDSSEAEHSCRGDGN-VKMAKYSPRGSLSDMSDGSSRDSPEPLPYDIKQEGMGLEMDIVSNTTSQMMFNLHSRLPAVLRTIEPGYSTNQQKQLHQETAASP------ANPQSAQRSVISYRSSIASYPVESQDIIPQEQQNFTQATEEQSRSLVSKQLERRP-FDSPSYECPDDEAAERQAYIVQRQTSRINAAPDLQIRPGEADETQEYHCPTSTRENDEPPVLTYEGGLSQEEYFEAHSGKDSSSTDGDPRSSDKEGSTDDESPSSSCSDTGSYHPHIFMTQNSFSPSQSKDGQAEVKGTALPHKLRLKHRAQS------DGRASSQDSPTTPPAHFQPLPQHPYLALSQPGGQSSAGFSKKDSSVESIECGRKESSMHNSRNKRHD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..:. :* *.*.* .* ..:* *.. ***. :* ** * .: : :* *::*** .*:*** ***::**:*************:***:**:**: *..** **::* :: :*.: . :. . ..... *.:. :. :* **. ** * ...*.:. *. * :. *.*.* . .:.: :. . .: *: :*.:: :* ::: :.: : : . ..:**:* :: :.:: ::*:. *. . .: . .::: *:: :.: :.. : .: : * *.. * .* : : . : .::** . . . :..: . ..: . . .. :** **. *...*.:..** ....: . . . *..: ** : : : ... .... * . :* * : : ::: ** .*.*. : : .. . ::.. * : ..: . : * **.: . : :", "identical_positions": 105, "similar_positions": 212, "identity": "14.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110930-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P78556-1", "uniprot_id": "CCL20_HUMAN", "id": "P78556-1", "name": "C-C motif chemokine 20", "aln": "MCCTKSLLLAALMSVLLLHLCGESEAASNFDCCLGYTDRILHPKFIVGFTRQLANEGCDINAIIFHTKKKLSVCANPKQTWVKYIVRLLSKKVKNM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PJ26-1", "uniprot_id": "A0A8M9PJ26_DANRE", "id": "A0A8M9PJ26-1", "name": "C-C motif chemokine", "aln": "--MMSKLVLTSSALLLLLCVCVNLSQSSPMRCCTMYSIHSLPLNRLMDYTLQDTTKACNIKAVIFTTIKNRQICANPDDPWVQKAISHIQMKNKSA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ..*:*:: :*** :* : . :* : ** *: : * : ::.:* * :.:.*:*:*:** * *: .:****.:.**: : :. * *. ", "identical_positions": 28, "similar_positions": 36, "identity": "29.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110930-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9Q9M8-1", "uniprot_id": "PWP2B_MOUSE", "id": "E9Q9M8-1", "name": "PWWP domain-containing protein 2B", "aln": "-----MEPRAGCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKKSGLFGLSPSTLLPLADNSSAVSCHGQAPEEGTGEVMQLETGPLHPHHKDPEKDQPPKTAVSEPPPPLIPPVPAGNLPPFPPYFEGAPFPHPLWLRNTYQQWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTVSPQEASPSPLNTPKPRRRLGS----GPDSEHRKPEEPEDSAVIATAAPRRS----------KREKREEDRVA-GERVPRSPVIKISYSTPQGKGEVVKIPSRVHGSVEPFCPQQSLQN--GSQDSEVSRDVEPRGGGDRPPSGSSASIPKLKLTRPVPPISDLPPPKIRLKPHRLGDGEHEPLYRAELVEELNGCPRGPLVSSPALFADGSSHGLEDLSSGSSGEDDDLKRFPQGKHGRDG-LAFLVDCPGRRTDCTSESVCSTDSLDELKSSGSEVTSPDTGDLSSGDSASVPSSSADTRQTVPPLTVRLHTQSVSRCVTEDGRTVAVGDIVWGKIHGFPWWPARVLDISLGQKEDG--EPSWQEAKVSWFGSPTTSFLSISKLSPFSEFFKLRFNRKKKGMYRKAITEAANATQHVAPEIRELLTQFEM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NUJ5-1", "uniprot_id": "PWP2B_HUMAN", "id": "Q6NUJ5-1", "name": "PWWP domain-containing protein 2B", "aln": "-----MEPRAGCRLPVRVEQVVNGALVVTVSCGERSFAGILLDCTKKSGLFGLPPLAPLPQVDESPVNDSHGRAPEEGDAEVMQLGSSSPPPARG----VQPPETTRPEPPPPLVPPLPAGSLPPYPPYFEGAPFPHPLWLRDTYKLWVPQPPPRTIKRTRRRLSRNRDPGRLILSTIRLRPRQVLCEKCKSTLSPPEASPGPPAAPRARRRLGS----GPDRELRKPEEPENGEPTAAATARRS----------KRERREEDRAP-AEQVPRSPVIKISYSTPQGKGEVVKIPSRVHGSLEPFRPQQAPQDD-GSQDPEVL-DRESR---DRPSCAPSASIPKLKLTRPVPAGADLPPPKIRLKPHRLGDSEHEPVYRAELVGELNGYLRD---SSPAPCADGPAGGLADLSSGSSGEDDDFKSCPQGPQGREG-LAFLVSCPEGRADCASESACSSDSLDEARSSGSEGTPADTGDLSPGHGASAPSVSREARQTVPPLTVRLHTQSVSECITEDGRTVAVGDIVWGKIHGFPWWPARVLDISLGQKEDG--EPSWREAKVSWFGSPTTSFLSISKLSPFSEFFKLRFNRKKKGMYRKAITEAANAARHVAPEIRELLTQFET", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IGL9-1", "uniprot_id": "A0A0R4IGL9_DANRE", "id": "A0A0R4IGL9-1", "name": "", "aln": "MQASPEELRAGSRLPVTVEQILNDTLVVTLRYREKSFTGILLDCSRKTGLFCLPDVVGKTEEPLILRPDCEVLSEESSSEPVSQPTQRP-----------KDENTEPEESPAPVPIPLQPG-QHTYPPYFEGAPFPQPIWVRHTYNQWVPQPPPRPIKRKKR---RSRDAGRLAISTIRLRPRQVLCEKCKNTLNSDEDSKDGPTLPKTSRKENSPHAEDDNTKTTSAKRKDDGEHNNRESKRREDSTVYDGKRFRKDKKEEEKFPSGDVIPHSPVIKISYSTPQGKGEVMKIPSRVHGSVKPFCPKQLLQNGHGDRDSSKETPKKLQPPMDAIRTGLTISIPKLKLPK--LPSPDAQSPKIRLRSRAEG-AEQMSVYEAELVDGARRRSPRVPNSGLPQSEDAEDKNSLELWSGSCG----------GEVERHGDLTLLINFRKRKADSSSLSVCSSDSLDESKSFSSDGTSPELCDLAPGDDISVSSSSQGEGKTVPPLTVRLHTRSMSKCVTEDGHAVTVGDVVWGKIHGFPWWPARILSISGTRREDGEVDAPWPEAKVSWFGSPTTSELSVAKLSPFREFFRSRFNRKKKGMYRRAIMEAAKAVGHMGAEITSLLAHCET", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ***.**** ***::*.:****: *:**:******::*:*** *. . . ... : *.. * * . : :* *.*.*: *: .* .:**********:*:*:*.**: ********.***.:* *.**.*** :****************.*:.. * * . *:. *: .* . : : ..:. ::. : **. :::::**:: . .: :*:*****************:*********::** *:* *: *.:*.. : : * . : *******.: . .* .*****:.: * .*: .:*.**** . *. . *. . :* ***.* * *.* *::*:. ::*.:* *.**:***** :* .*: *..: **:.*.. *..* * :***********:*:*.*:****::*:***:**************:*.** ::*** :..* ************* **::***** ***: ***********:** ***:*. *:..** .**:: * ", "identical_positions": 273, "similar_positions": 158, "identity": "43.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110930-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ET55-1", "uniprot_id": "NOCT_RAT", "id": "Q9ET55-1", "name": "Nocturnin", "aln": "MYQSPRRLCSALLLRDAPGLRRTL-------------VPGPRRTLAPPVLGSRPASPQLQAAAS----------------------------------------GAARSRPRTVSPMGNGTS-----------------------RLYSALAKTINSSAAAQHPE-------------------YLVSA-DPEHL--------------------------------------EPIDPKE-------------LLEECRAVLH---TRPPRYQRDFVDLRTDCSSSHP---------------------PIRVMQWNILAQALGEGKDNFVQCPVEALKWEERKCLILEEILAYQPDILCLQEVDHYFDTFQPLLSRLGYQGTFFPKPWSPCLDVEHNNGPDGCALFFLQSRFKLINSTNIRLTAMTLKTNQVAIAQTLECKESGRQFCIAVTHLKARTG--WERFRSAQGCDLLQNLQNITEG--------AKIPLIVCGDFNAEPTEEVYKHFASSSLN-LNSAYKLLSPDG------------------QSEPPYTTWKIRTSGECRHTLDYIWYSRHALSVTSALDLLTEEQIGPNRLPSFHYPSDHLSLVCDFSFNEEPDELL-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35710-1", "uniprot_id": "NOCT_MOUSE", "id": "O35710-1", "name": "Nocturnin", "aln": "MYQSPRRLCSALLLRDAPGLRRTL-------------VPGPRRTLAPPVLGSRPKSPQLQAAAAS---------------------------------------GAARSRPRTVSSMGNGTS-----------------------RLYSALAKTVNSSAAAQHPE-------------------YLVST-DPEHL--------------------------------------EPIDPKE-------------LLEECRAVLH---TRPPRYQRDFVDLRTDCSSSHS---------------------PIRVMQWNILAQALGEGKDNFVQCPVEALKWEERKCLILEEILAYQPDILCLQEVDHYFDTFQPLLSRLGYQGTFFPKPWSPCLDVEHNNGPDGCALFFLQNRFKLISSTNIRLTAMTLKTNQVAIAQTLECKESGRQFCIAVTHLKARTG--WERFRSAQGCDLLQNLQNITQG--------AKIPLIVCGDFNAEPTEEVYKHFASSSLN-LNSAYKLLSPDG------------------QSEPPYTTWKIRTSGECRHTLDYIWYSRHALSVTSALDLLTEEQIGPNRLPSFHYPSDHLSLVCDFSFNEEPHELF-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UK39-1", "uniprot_id": "NOCT_HUMAN", "id": "Q9UK39-1", "name": "Nocturnin", "aln": "MFHSPRRLCSALLQRDAPGLRRLP-------------APGLRRPLSPPAAVPRPASPRLLAAASAAS-------------------------------------GAARSCSRTVCSMGTGTS-----------------------RLYSALAKTLNSSAASQHPE-------------------YLVSP-DPEHL--------------------------------------EPIDPKE-------------LLEECRAVLH---TRPPRFQRDFVDLRTDCPSTHP---------------------PIRVMQWNILAQALGEGKDNFVQCPVEALKWEERKCLILEEILAYQPDILCLQEVDHYFDTFQPLLSRLGYQGTFFPKPWSPCLDVEHNNGPDGCALFFLQNRFKLVNSANIRLTAMTLKTNQVAIAQTLECKESGRQFCIAVTHLKARTG--WERFRSAQGCDLLQNLQNITQG--------AKIPLIVCGDFNAEPTEEVYKHFASSSLN-LNSAYKLLSADG------------------QSEPPYTTWKIRTSGECRHTLDYIWYSKHALNVRSALDLLTEEQIGPNRLPSFNYPSDHLSLVCDFSFTEESDGLS-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PJP7-1", "uniprot_id": "A0A8M9PJP7_DANRE", "id": "A0A8M9PJP7-1", "name": "Nocturnin", "aln": "-------------------------------------------------------------------------------------------------------------MEVVACSMGSGSS-----------------------SLYSALAKSISRSPLPHSCG-------------------STYSPGDNLNLDQ------------------------------------DPADPLE-------------LLQECREALR---ERPAHLKRAFV--QTGHGDARR---------------------TIRVMQWNVLAQALGEGMDNFVQCPLDALNWPERKYMILEEILTYKPDILCLQEVDHYFDMFQPVLATLGYQSSFCPKPWSPCLDVENNNGPDGCALFFNHKRFQLVNTTHLRLSAMMLKTNQVAIVAALRCRSTGRVFCVGVTHLKARSG--WEVLRSAQGSDLLRNLRNITQKIETEENAESAIPLIVCGDFNAEPSEDVYRNFATSSLG-LDSAYKLLSTDG------------------KTEPPYTTWKIRPSGESCHTLDYVWYSHRAFDVNAVLDFPTAEQIGPNRLPSYNYPSDHLSLVCDFCFTDPVN----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JQX3-1", "uniprot_id": "NOCT_DROME", "id": "A8JQX3-1", "name": "Nocturnin", "aln": "MDQKTTGLRENYGHRRQPALGKAMPVTALLLNLESNPLDYSRNDIGAELLEDDDKPPQLFSVTDEPPSPNEEDYKPPNHHEDDGKLAGERHREIPCSNCLKTAPGHLIDRQSAINEMCQRLCGPECRRPQGLTLDGVRQDFLRQYEIAEAVAKTSAMTSTVQMKQRLAARKLEFEKEMEMDEQLGVASPRNDINLGQSSTVAATGMGEFEFEPPRDLLLYLVRMGSFNSAPKINNVDSQDDGLVLPSGLSTPALLQHVQQLRGGGIEQPSLLTRGFLKPLLADEDVADGLRCLKLNSVSRVCSAPVEGDDIRLLQWNILSQTLGQHNDGFVRCPEEALTWEHRKYLIVQEILQNQPDVICLQEVDH-FKFLQTVLGSQNYAGIFFPKPDSPCLYIEQNNGPDGCAIFYKRDKLQLQGYDTRILEVWRVQSNQVAIAARLRMRSSGREFCVATTHLKARHGALLAKLRNEQGRDLIRFVKQFAGD----------TPLLLCGDFNAEPVEPIYATILGCDLLRLGSAYADVKLDREEILHPNADVGEFVAKSMKREPPYTTWKIREEGEECHTIDYVFYTPDRLKIKNCLDFPAGEQIGKNRTPSFQYPSDHFSLVCDFELLPPTENGKESGSGSGSDGENETEVEGSKHGSIQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . : .*:**: :. : *. : :* : *. : **:. : :*. * *: . **::***:*:*:**: *.**:** :**.* .** :*::*** :**::******* *. :*.:*. .* . * *** **** :*:********:*: :.:::* . * . :::*****. *. :.:** **:..****** * :*. ** **:: ::::: **::******** * :* : ..* *.*** :. * : ********** .** **:**::*: :.: **: : **** ** **::*****:****** : . ", "identical_positions": 146, "similar_positions": 102, "identity": "22.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-110930-9", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BHN3-1", "uniprot_id": "GANAB_MOUSE", "id": "Q8BHN3-1", "name": "Neutral alpha-glucosidase AB", "aln": "MAAIAAVAARRRRSWLSLVLAYLGVCLGITLAVDRSNFKTCDESSFCKRQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQGLQKNMTRIRIDELEPRRPRYRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILTAQPFRLDLLEDRSLLLSVNARGLMAFEHQRAPRVPQESKDPAEGNGAQPEATPGDGDKPEETQEKAEKDEPGAWEETFKTHSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTLVSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPESRLSFQHDPETSVLILRKPGVSVASDWSIHLR------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14697-1", "uniprot_id": "GANAB_HUMAN", "id": "Q14697-1", "name": "Neutral alpha-glucosidase AB", "aln": "MAAVAAVAARRRRSWASLVLAFLGVCLGITLAVDRSNFKTCEESSFCKRQRSIRPGLSPYRALLDSLQLGPDSLTVHLIHEVTKVLLVLELQGLQKNMTRFRIDELEPRRPRYRVPDVLVADPPIARLSVSGRDENSVELTMAEGPYKIILTARPFRLDLLEDRSLLLSVNARGLLEFEHQRAPRVSQGSKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEPGAWEETFKTHSDSKPYGPMSVGLDFSLPGMEHVYGIPEHADNLRLKVTEGGEPYRLYNLDVFQYELYNPMALYGSVPVLLAHNPHRDLGIFWLNAAETWVDISSNTAGKTLFGKMMDYLQGSGETPQTDVRWMSETGIIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVDPHIKVDSGYRVHEELRNLGLYVKTRDGSDYEGWCWPGSAGYPDFTNPTMRAWWANMFSYDNYEGSAPNLFVWNDMNEPSVFNGPEVTMLKDAQHYGGWEHRDVHNIYGLYVHMATADGLRQRSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGLVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIRDALGQRYSLLPFWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYLPGQGEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSECMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSADPEGHFETPIWIERVVIIGAGKPAAVVLQTKGSPESRLSFQHDPETSVLVLRKPGINVASDWSIHLR------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1Q6Z9-1", "uniprot_id": "F1Q6Z9_DANRE", "id": "F1Q6Z9-1", "name": "Neutral alpha-glucosidase AB", "aln": "------MAANSIERMGLLSVLCVSLFFSSTFAVDRGSFKTCDQSSFCKRQRTLKPGQSPYRALLDTLELSDSRLTLQLINDNNKVHLLLELYRLQGNMTRVKINELKPLKPRFEVPDVLIADPPTEPLSVLSQDDNGLVLSLGAESQRLIVSARPFRLDIMEGPEVLLSLNSRGLLAFEHLRLRKDTQAQPDGAEVKES-TEADQQQAEGEKDEDGENDKDEDGLWDESFKAHADTKPNGPTSISLDFSLPGVEHVYGIPEHADNLKLKTTDGGDPYRLYNLDVFQYELYNPMALYGSVPVMIAHNTQRTMGIFWLNAAETWVDISSNTAGKTVFGKMLDFVQGSSETPQTDVRWISESGIIDVFIMLGPKPSDVFSQYASLTGTQSFPPLASLAYHQCRWNYNDQDDVKSVDEGFDQHDIPYDFIWLDIEHADGKRYFTWDPHKFPEPKEMLQGLMEKRRKMVAIVDPHIKVDSDYKIHNEITNKDFYVKNSDGRNYEGWCWPGNSGYPDFTNPEMRAWWASMFSYDQYEGSMENLFTWNDMNEPSVFNGPEITMHKDAIH-GKWEHRDVHNIYGLYVQKATAEGQIQRSGGVERPFVLTRAFFAGSQRYGAVWTGDNAADWGHLKISIPMCLSLGLVGISFCGADVGGFFNNPSTELLVRWYQTGAYQPFFRAHAHLDTTRREPWLFGPENTALIREAIRQRYALLPYWYQLIYQAHTTGMPVMRPLWVDYPKETATFTIDDEFLIGRDLLVHPVTEEGSRGVTAYLPGAGEVWYDVHTFQKHNGAQNLYIPVTLSSIPVFQRGGSIIPRKDRIRRSSACMENDPYTLYVALSPKKFAEGELYIDDGHSFNYDTKSEFIHRKLTFANNSLTSRNLCPDCKFSTSSWVEKVVILGASKPRKVLLKVDGK-ETPVEFEFDASMSVLTLRKPGINAGMDWTILLQSQRNDL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**. . * : :.: :. *:****..****::********:::** ********:*:*. . **::**:: .** *:*** ** ****.:*:**:* :**:.*****:**** *** .:*:*.: *::. . ::*::*:*****::*. .:***:*:***: *** * : .* . * ** . : .* :.: :: : : :*** * *:*:**:*:*:** ** *:.*******:***********.*:**.*:**:************** ***********::**. :* :**********************:****:*::***.******:**:**:******::***. *** *********::*** **.***.****.*: ** .**:***:*::* *.****************** :**:* **: * .****:************.*::*:*: * .:***. ** :********.:.******* *****:.***:*:**** **:.**************:** *** * * *****:********: ***:* *****:******:****:****:********:*:*.************.***:***********:**..******** *************** ******: .: **:*: ***:***:** *:**** *:********:**:: :**.*:*::::* **:***:: *::** .**** *****::::***:*.*.**:**************:*:** *:**** **::** **:*****: *:***::****:***:*: **: *:::*:..:*.* . *. ::.*. *:*:***:**.** *:*:..*. *: :.*:.*.. *** *****:... **:* *: ", "identical_positions": 583, "similar_positions": 234, "identity": "61.37%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111003-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PRE5-1", "uniprot_id": "PRSR1_MOUSE", "id": "Q5PRE5-1", "name": "Proline and serine-rich protein 1", "aln": "MDKKSFETVLDEIRKAVLTEYKLKAIEYVHGYFSSEQVVDLLRYFSWAEPQLKAMKALQHKMVAVHPAEVVSILSCFTFSKDKLAALELLASNIVDAQNSRPIEDLFRINMSEKKRCKRVLEQASKAGCKAPHAMISSCGTFPGNPYPKGKPSRINGIFPGTPLKKDGEEITNEGKGIAARILG-PSKPPPSTYNPHKPVPYPIPPCRPHATIAPSAYNNAGLVPLANVIAPGVPPPPPYTPNPAGTDNEDLSSQSKP-TQSQTFSTPASQLFSPHGSSNPSTPAATPVPAVSPAKAVNHPSVSAAATGAGMSATNTALAVFP--------TPQPNTPNPTVIRTPSVPATPVTSTHSTTPTPVPSVFSGLVPLPGLSATPTLPTQAS-SISRVTLASSETFASTCAPFSGHS-SASSTAGSASNPITAPLSSVFAGLPLPFPPASHSIATPTPSVIA----SAAGPHGVNSPLLSALKGFLTSNDTHLINSSALPSAVTSGLASLSSLPNRNSDSPASATNKCYPPAAVPAAQRSSTPGLAMFPGLQSPVASATSVAPTLPAQSPLATPS---TAVPVSCGSSGSLLHGPHAGG----ISSAPAAATMPVMIKSEPTSPPPSAFKGPAHPGTPVRGTLGLS--GALGRGYPTTSVPISVSTCLN--PALSGLSSLSTPLAG-----SMSLPPHASSTPIAPVFTALPPFTSLTNSFPLPGSPSLNPAVSLAG------SSTTTTSAAVHPSS-ATVRSVLPTSN-ASPAAFPLNLSTAVPSLFAVTQGPLPTSNPSYPGFPVSSAPSG-APTLPSFPGLQ-APSTVA-VTPLP------VAASAPSPAPVLPGFASAFSSNFNSALVAQAGLSSGLQAAGSSVFPGLLSLP-GIPGFSQAPPQSSLQELQHSAAAQSALLQQVHSASALESYPAQADGFPSYPSTPGTPFSLQTGLSQS-GWQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86XN7-1", "uniprot_id": "PRSR1_HUMAN", "id": "Q86XN7-1", "name": "Proline and serine-rich protein 1", "aln": "MDKKSFEMVLDEIRKAVLTEYKLKAIEYVHGYFSSEQVVDLLRYFSWAEPQLKAMKALQHKMVAVQPTEVVNILNCFTFSKDKLVALELLASNIIDAQNSRPIEDLFRVNMSEKKRCKRILEQAFKGGCKAPHAMISSCGTIPGNPYPKGRPSRINGIFPGTPLKKDGEECTNEGKGIAARILG-PSKPPPSTYNPHKPVPYPIPPCRPHATIAPSAYNNAGLVPLANVIAP---PPPPYTPNPVGTENEDLSNPSKP-IQNQTFSTPASQLFSPHGS-NPSTPAATPVPTASPVKAINHPSASAAATVSGMNLLNTVLPVFPGQVSSAVHTPQPSIPNPTVIRTPSLPTAPVTSIHSTTTTPVPSIFSGLVSLPGPSATPTAATPTPGPTPRSTLGSSEAFASTSAPFTSLPFSTSSSAASTSNPNSASLSSVFAGLPLPLPPTSQGLSNPTPVIAGGSTPSVAGPLGVNSPLLSALKGFLTSNDTNLINSSALSSAVTSGLASLSSLTLQNSDSSASAPNKCYAPSAIPTPQRTSTPGLALFPGLPSPVANSTSTPLTLPVQSPLATAASASTSVPVSCGSSASLLRGPHPGTSDLHISSTPAATTLPVMIKTEPTSPTPSAFKGPSHSGNPSHGTLGLS--GTLGRAYTSTSVPISLSACLN--PALSGLSSLSTPLNGSNPLSSISLPPHGSSTPIAPVFTALPSFTSLTNNFPLTGNPSLNPSVSLPGSLIATSSTAATSTSLPHPSSTAAVLSGLSASAPVSAAPFPLNLSTAVPSLFSVTQGPLSSSNPSYPGFSVSNTPSV-TPALPSFPGLQ-APSTVAAVTPLP------VAATAPSPAPVLPGFASAFSSNFNSALVAQAGLSSGLQAAGSSVFPGLLSLP-GIPGFPQNPSQSSLQELQHNAAAQSALLQQVHSASALESYPAQPDGFPSYPSAPGTPFSLQPSLSQS-GWQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5S1-1", "uniprot_id": "A0ACD6B5S1_DANRE", "id": "A0ACD6B5S1-1", "name": "", "aln": "MDKKSFDIVLDEIRKCVLTDQRIKAIEQVHGYFSSEQVIDILKYFSWAEPQIKAVKALQHKMVAIPTTKVANILNCFTFSKDRIIVLELIALNISDAQNYRPVEDAFRIHLSEKKRARRILEQVCKVGCKAPVAMISSCGMIPGNPYPKGKPSQVTGTFPGIPAKKEGEDVNLDGKGIALRIIGGSSKPSPSSYNPHRPVPYPIPPCRPHATIAPSAYNNAGLVSVGGVITAN-VPPPPYRATPN------LAGYSRPASQNPTANITGTPAISPRGS-TPSTPVTSQPQPTTPITPVFPGMVPSQN------------PVTP--------SPTP-APSPSVIKGPPIGSPQVASNSSGHTTPVPSPFPGMPPS-GRNTPSVIKSHTP----------------------------SGTPCSTPGPSTGIPPSPFHNAPRSETPSSG--ITPTPRATG----DSMNTHGAMG--LPSKKGYPPSSDS----QSALLYPGTPSTQSHSVIR----SYTPSGMSALAPGQSVPSMQGVGSP----------------KPSPGLTSQATLGSPAG----AYFNEQHTSSMAR--HGGG-------------------SGSNSPVPSAFKGPSRSGTPSLSSLVMPNSAVLARPVGMAHGSPSPQSNLPGTAGIAGLHSLPSALGS------------QSGSSPAPHFAAMSPFPGAQSSISTPSTPTP-------------------------PVS--SVYTGLAHSSAPSHTPFGLGLTTAP----SVFPGLPPGPNPAFPGFGGSGSPAAGSPVLSSLMGIPGASSSVATVAPLQAAVAAAAAAGVPSSSPVLPGFASAFSSNFNPALVGQPGLTGSLQPPGGAGFPGLLSFPPGMPGFSSAASPAALSGLHN-SAMQSALLQ-AHSASALDSY-AQPNGFPNYPAAAGSSFPLQPGLHPSLGWQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******: *******.***: ::**** **********:*:*:********:**:*********: .::*..**.*******:: .***:* ** **** **:** **:::*****.:*:***. * ***** ******* :********:**::.* *** * **:**: . :***** **:* .***.**:****:**************************.:..**:. ***** ..* *:. *:* *. * . ..: :**:** .****.:: ..:* ..: ..: .* * :* * *.*:**: *.: :. *:* * .***** *.*: . * .:... : :. *.:. *:..* :. .* * . * . .*:* .*** . . .. *. . *.: **: .*.*: .*** . *.. * * : . ..*. . . ::*: * .:* . . *. *:.*.:.: . .. :.*: : * * : ..** *******::.*.* .:* :. ..*.* : . * .: * ..::** **.:.* . *.:. ** *:*:..*.. ..:. ...*: * * :* : *. * * :.* *.*:** :* * . .**::*** *.:*: :*.*.*: *: *.*:** *:** .** .**.:***************.***.*.**:..**..*.: ******:* *:***.. .. ::*. *:: :* ****** .******:** **.:***.**::.*:.*.**..* * ***", "identical_positions": 367, "similar_positions": 259, "identity": "38.07%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111007-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZEH0-1", "uniprot_id": "D3ZEH0_RAT", "id": "D3ZEH0-1", "name": "", "aln": "----------------------------------------MAALGHTLPFYTGPKPTFPMDTTLAVIITIFLTALVTFIIILPGIRGKTRLFWLLRVVTSLFIGAVILAVNFSSEWSVGHINTNTTYKAFSPKRVSVHVGLQIGLGGLNITLTGTPVQQLN-ETINYNEEFTWRLGKSYAEEYAKALEKGLPDPVLYLAEKFAP-RSPCGLYNQYRLAGHYASAMLWVAFLCWLLANVMLSMPVLVYGGHMLLATGLFQLLALFFFSMTTSLMS-CPLRLGTAVLYTHHGPAFWITLATGLLCILLGLVMAVAHRMQPHRLKALFNLSS-EDPMLEWGSE---EGGLLSPH-YRSIAESPETQDIPMSEASS-ETCLKEECLKESDCSL-------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VE49-1", "uniprot_id": "DOXA1_MOUSE", "id": "Q8VE49-1", "name": "Dual oxidase maturation factor 1", "aln": "----------------------------------------MAALGHTLPFYTGTKPTFPMDTTLAVIITIFLTALVTFIIILPGIRGKTRLFWLLRVVTSLFIGAVILAVNFSSEWSVGHVNANTTYKAFSPKWVSVDVGLQIGLGGVNITLTGTPVQQLN-ETINYNEAFAWRLGRSYAEEYAKALEKGLPDPVLYLAEKFTP-RSPCGLYNQYRLAGHYASAMLWVAFLCWLLANVMLSMPVLVYGGHMLLATGLFQLLALFFFSMTTSLISPCPLRLGTAVLHTHHGPAFWITLATGLLCILLGLVMAVAHRMQPHRLKAFFNQSS-EDPVLEWGSE---EGGLLSPH-YRSIAESPETQDIPMSVASS-ETCFKEEHPKESDCSL-------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q1HG43-1", "uniprot_id": "DOXA1_HUMAN", "id": "Q1HG43-1", "name": "Dual oxidase maturation factor 1", "aln": "----------------------------------------MATLGHTFPFYAGPKPTFPMDTTLASIIMIFLTALATFIVILPGIRGKTRLFWLLRVVTSLFIGAAILAVNFSSEWSVGQVSTNTSYKAFSSEWISADIGLQVGLGGVNITLTGTPVQQLN-ETINYNEEFTWRLGENYAEEYAKALEKGLPDPVLYLAEKFTP-RSPCGLYRQYRLAGHYTSAMLWVAFLCWLLANVMLSMPVLVYGGYMLLATGIFQLLALLFFSMATSLTSPCPLHLGASVLHTHHGPAFWITLTTGLLCVLLGLAMAVAHRMQPHRLKAFFNQSVDEDPMLEWSPE---EGGLLSPR-YRSMADSPKSQDIPLSEASSTKAYCKEAHPKDPDCAL-------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZEJ5-1", "uniprot_id": "D3ZEJ5_RAT", "id": "D3ZEJ5-1", "name": "", "aln": "MLSLIPAAGGHTLPQLVLGEEHRDITQVPHLHDALSGTTWMTAWDGVLPFYPQPRHAAGFSVPLLIVILVFLSLAASFLFILPGIRGHSRWFWLVRVLLSLFIGAEIVAVHFSGDWFVGRVWTNTSYKAFSTSRVQVHVGLHVGLEGVNITLRGTPMQQLN-ETIDYNEQFTWRLNEDYTKEYVQALEKGLPDPVLYLAEKFTP-NSPCGLYHQYHYAGHYAGATLWVAFCFWIIANALLSMPAPLYGGLALLITGAFTLFSVFAFASISSVPL-CHFRLGSAALTPHYGASFWVTLATGILSLLLGGLVVILHYTRPSVLRALLDQNVKDCSNQADGNS---HFILDNPQ-HRQSK-TPDLN-VTTLL---------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D311-1", "uniprot_id": "DOXA2_MOUSE", "id": "Q9D311-1", "name": "Dual oxidase maturation factor 2", "aln": "----------------------------------------MTAWDGVLPFYPQPRHAASFSVPLLIVILVFLSLAASFLFILPGIRGHSRWFWLVRVLLSLFIGAEIVAVHFSGDWFVGRVWTNTSYKAFSPSRVQVHVGLHVGLAGVNITLRGTPRQQLN-ETIDYNERFTWRLNEDYTKEYVHALEKGLPDPVLYLAEKFTP-SSPCGLYHQYHLAGHYAAATLWVAFCFWIIANALLSMPAPLYGGLALLTTGAFTLFGVFAFASISSVPL-CHFRLGSAVLTPYYGASFWLTLATGILSLLLGGAVVILHYTRPSALRSFLDLSVKDCSNQAKGNS---PLTLNNPQ-HEQLK-SPDLN-ITTLL---------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q1HG44-1", "uniprot_id": "DOXA2_HUMAN", "id": "Q1HG44-1", "name": "Dual oxidase maturation factor 2", "aln": "----------------------------------------MTLWNGVLPFYPQPRHAAGFSVPLLIVILVFLALAASFLLILPGIRGHSRWFWLVRVLLSLFIGAEIVAVHFSAEWFVGTVNTNTSYKAFSAARVTARVRLLVGLEGINITLTGTPVHQLN-ETIDYNEQFTWRLKENYAAEYANALEKGLPDPVLYLAEKFTP-SSPCGLYHQYHLAGHYASATLWVAFCFWLLSNVLLSTPAPLYGGLALLTTGAFALFGVFALASISSVPL-CPLRLGSSALTTQYGAAFWVTLATGVLCLFLGGAVVSLQYVRPSALRTLLDQSAKDCS-QERGGS---PLILGDPL-HKQAA-LPDLKCITTNL---------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58IYU3-1", "uniprot_id": "A0AC58IYU3_DANRE", "id": "A0AC58IYU3-1", "name": "", "aln": "-----------------MRVTEPLANTVLLSALVLACGGKMTFYDGIYPFYPLQRSPFMINISLLVAILVFSVLAVSFLFILPGIRGRSRWFWMFRIFISLFIGVVLVVLNFTGDWAEARVKANTTYKSFSTAVVSAEVGLHVGLYGINITLKGEPVTQIN-ETINYNEIISWSS--SVDEQYGDALERGLPNPILYIAEKFTY-NSACGLIYQYSYSARFASANLWTAFCCWLLANILFSMPVILYAGYMMIATAAFIFFSVASFSTIYNVSP-CDFSIGSEALRTDYSHSFWLALATGLLCAVIGLLVVLLDCLFPARMREAFSVGVDDEDDECCADEGYLNSGFLEGV-IHDDVTPAENNSLPQQITTLTRL---------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJQ7-1", "uniprot_id": "Q9VJQ7_DROME", "id": "Q9VJQ7-1", "name": "", "aln": "---------------------------------MKGWFDAFRDDGGPTLYSFSNRTPVTGDVSIVAVSVLFATFYVAFLVIFPGVR-KQKFTTFSTVTLSLFVGLVILITRLGSAWHVAHATIIAPYKAFSREKLPARIGTHIGLMHVNVTLTAIPIGNWTPPDIDYNERFTWEGANDMSANYRHALQRGLPFPILTVAEYFSLGREGFSWGGQYRAAGYFASIMLWASLASWLLMNLLL-IAVPRYGAYMKALTGALLVCTTVGYHCLLPKRP-LSIHLEGGRLEFHFGWCYWLVLVAGILCFIAGVLISIIDLVWPHTFSTVLEVYYGTPYDRHVILEESSDVRYRKPRNSRSLEDPPGLGSRILRRLSSKARDLQPGTAPRRDSPAGVSSSGGVENKGFQSDAPKSPWRYPFRRSQQMAQQQHSHPLHQHPLQQHHQHHQHHHQQQLQFVGGPVVQHPMHHMQRTMSQDSGSSIASAAVQISPLHKHALARMLPNPPVERIRDMDHW", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : . . .: :* .:*:.*:**:* : : : : ***:* :: .: . * . :.**:** : . : :** :*:** . * : . *:*** ::* . :* .**::*** *:* :** *: . . ** :. ::. **.:: *:: * :: .. *.. *. : . : : * .. .:*:.*.:*:*. . * : . * : :. . . .. . ", "identical_positions": 52, "similar_positions": 93, "identity": "10.2%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111011-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B0BMS9-1", "uniprot_id": "B0BMS9_RAT", "id": "B0BMS9-1", "name": "", "aln": "MASPAATSVRPPRPKKEPQTLVIPKNAAEEQKLKLERLMKNPDKAVPIPEKMNEWAPRPPPEFVRDVMGSSAGAGSGEFHVYRHLRRREYQRQDYMDAMAEKQKLDAEFQKRLEKNKIAAEEQTAKRRKKRQKLKEKKLLAKKMKLEQKKQKEEPSQCQEQQTSSSEEASGAEEEEEEPSVVIMGR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CWV6-1", "uniprot_id": "PKRI1_MOUSE", "id": "Q9CWV6-1", "name": "PRKR-interacting protein 1", "aln": "MASPAAASVRPPRPKKEPQTLVIPKNAAEEQKLKLERLMKNPDKAVPIPEKMNEWAPRAPPEFVRDVMGSSAGAGSGEFHVYRHLRRREYQRQDYMDAMAEKQKLDAEFQKRLEKNKIAAEEQTAKRRKKRQKLKEKKLLAKKMKLEQKKQKEEPSQCQEQHASSSDEASETEEEEEEPSVVIMGR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H875-1", "uniprot_id": "PKRI1_HUMAN", "id": "Q9H875-1", "name": "PRKR-interacting protein 1", "aln": "MASPAASSVRPPRPKKEPQTLVIPKNAAEEQKLKLERLMKNPDKAVPIPEKMSEWAPRPPPEFVRDVMGSSAGAGSGEFHVYRHLRRREYQRQDYMDAMAEKQKLDAEFQKRLEKNKIAAEEQTAKRRKKRQKLKEKKLLAKKMKLEQKKQ-EGPGQPKEQGSSSSAEASGTEEEEEVPS-FTMGR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q568A0-1", "uniprot_id": "PKRI1_DANRE", "id": "Q568A0-1", "name": "PRKR-interacting protein 1 homolog", "aln": "MAVENKDARPGKALKKESQPLIIAKTPAEEQRLKLERLMRNPDKAAPIPEKPKEWNPRAPPEFVRDVMGSSAGAGSGEFHVYRHLRRREYQRQDFLERLSEKQKLDEEYKEKLIENQKAAEDRTAKRRKKREKLKQKKLMAKKAKME--SQKEEDSE--KSSSSSASEGEEKDDDAEVPS-FIMGKR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : ***.*.*:*.*..****:*******:*****.***** .** **.***********************************::: ::****** *::::* :*: ***::********:***:***:*** *:* .* * .: :. :**: *.. ::: * ** . **: ", "identical_positions": 110, "similar_positions": 43, "identity": "58.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111012-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAL8-1", "uniprot_id": "F1MAL8_RAT", "id": "F1MAL8-1", "name": "", "aln": "MDAPYDGTEVTVLMEEIEEAY-YTSPGPPKKKKKYKIHGEKAKKPRSAYLLYYYDIYLKVQQELPHLPQSEINKKISESWRLLSVAERSYYLEKAKLEKEGLDPNSKLSALTAVVPDIPGFRKILPRSEYIIIPKSTLQ--EDRSCPQLELCVAQNQMSPKGSTLMPNASPEVVASHAGMAEQCLAVEALAEEVGALSQPGAMQEIATSEILSHDVLLEEASLEVGESHQPYQTSLVIEETLVNGSSDLPTGSLAVPHSQVGESLSVVTVMRDSSENNPSAPTTQFIMLPLPAYSVVENPSSIKLTTTYTRRGHGTCTSPGCSFTYVTRHKPPKCPTCGNFLGGKWIPKEKPAKVKVELASGVSSKGSVIKRNQQSVTTEQNPSKENASKLTLENSEAVSQLLNVAPPREGGEDSEWEEVIVSDAHVLVKEVPGNCNTAVTKMPVVKSGIQAEVSLGTTENDSPGPDIPPSAEGTSTSSLLQAHKKSSGVDLFTTGPKAPELKGRARGKPSLLAAARPMRAILPAPTSVGRGSSMGLPRARQAFPL-DKTPPVRTCGLKPSTLKQLGQPIQQPPSTGEVKLSSCASSRTPQLKIVEVKPDMFPPYKYSCTVTLDLGLATSRGRGKCKNPSCSYVYTNRHKPRICPSCGFNLAKDRTEKTTKAIEASSPHPDVPSTTEPLNAAQREIQRQSTLQLLRKVMQIPENESELAEVFALIHELNSSRLILSNVSEETVTIEQTSWSNYYESPSTQCLLCSSPLFKGGQNSLAGPQECWLLTANRLQVVTAQVKMCLNPHCLALHSFMDIYTGLFNVGNKLLVSLDLLFAIRNQIKLGEDPRVSVGVVLKSVQEQTEKTLTSEELSQLQDLLCNGYWAFECLTVRDYNDMICGICGVAPKVEMAQRNEENVLALKSVEFTWPEFLGSSEVNVEDFWTTMETEVIEQVAFPASIPITKFDASVIAPFFPPLMRGAVVVNTEKDKNLDVQPVPGNGSALVRLLQEGTCKLEELGSYGGEELQFLLEQCDIPFGPEDSRDQLCFSLLALYESVQNGAR-ARPPPTHFTGGKIYKVCPHQVVCGSKYLVRGESARDHVDLLASSRHWPPVYVVDMATPVALCADLCYPELTSQMWGKNQGCFSNPTEPVVSVSCPELLDQHYSVDVTEAENS-VQHPVTKTATRRIIHANTKPDPSDPSAGHRSLSLCPELAPYA----STTDSKLSSIRQRPIAFDNATHYYLYNRLMDFLTSREIVNRQIHDIVQSCQPGE-VVIRDTLYRLGVAQIKTETQ--EDGEEEEVPSVVE-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q12766-1", "uniprot_id": "HMGX3_HUMAN", "id": "Q12766-1", "name": "HMG domain-containing protein 3", "aln": "MDASYDGTEVTVVMEEIEEAYCYTSPGPPKKKKKYKIHGEKTKKPRSAYLLYYYDIYLKVQQELPHLPQSEINKKISESWRLLSVAERSYYLEKAKLEKEGLDPNSKLSALTAVVPDIPGFRKILPRSDYIIIPKSSLQ--EDRSCPQLELCVAQNQMSPKGPPLVSNTAPETVPSHAGMAEQCLAVEALAEEVGALTQSGAVQEIATSEILSQDVLLEDASLEVGESHQPYQTSLVIEETLVNGSPDLPTGSLAVPHPQVGESVSVVTVMRDSSESSSSAPATQFIMLPLPAYSVVENPTSIKLTTTYTRRGHGTCTSPGCSFTYVTRHKPPKCPTCGNFLGGKWIPKEKPAKVKVELASGVSSKGSVVKRNQQPVTTEQNSSKENASKLTLENSEAVSQLLNVAPPREVGEESEWEEVIISDAHVLVKEAPGNCGTAVTKTPVVKSGVQPEVTLGTTDNDSPGADVPTPSEGTSTSSPLPAPKKPTGADLLTPGSRAPELKGRARGKPSLLAAARPMRAILPAPVNVGRGSSMGLPRARQAFSLSDKTPSVRTCGLKPSTLKQLGQPIQQPSGPGEVKLPSGPSNRTSQVKVVEVKPDMFPPYKYSCTVTLDLGLATSRGRGKCKNPSCSYVYTNRHKPRICPSCGVNLAKDRTEKTTKAIEVSSPLPDVLNATEPLSTAQREIQRQSTLQLLRKVLQIPENESELAEVFALIHELNSSRLILSNVSEETVTIEQTSWSNYYESPSTQCLLCSSPLFKGGQNSLAGPQECWLLTASRLQTVTAQVKMCLNPHCLALHSFIDIYTGLFNVGNKLLVSLDLLFAIRNQIKLGEDPRVSINVVLKSVQEQTEKTLTSEELSQLQELLCNGYWAFECLTVRDYNDMICGICGVAPKVEMAQRSEENVLALKSVEFTWPEFLGSNEVNVEDFWATMETEVIEQVAFPASIPITKFDASVIAPFFPPLMRGAVVVNTEKDKNLDVQPVPGSGSALVRLLQEGTCKLDEIGSYSEEKLQHLLRQCGIPFGAEDSKDQLCFSLLALYESVQNGAR-AIRPPRHFTGGKIYKVCPHQVVCGSKYLVRGESARDHVDLLASSRHWPPVYVVDMATSVALCADLCYPELTNQMWGRNQGCFSSPTEPPVSVSCPELLDQHYTVDMTETEHS-IQHPVTKTATRRIVHAGLQPNPGDPSAGHHSLALCPELAPYATILASIVDSKPNGVRQRPIAFDNATHYYLYNRLMDFLTSREIVNRQIHDIVQSCQPGE-VVIRDTLYRLGVAQIKTETE--EEGEEEEVAAVAE-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FFB0-1", "uniprot_id": "E7FFB0_DANRE", "id": "E7FFB0-1", "name": "", "aln": "MEAIYGEMEVESCYTLLELPS----PKKKRKSKGSVENSDKPKKPRSAYLLYYFDVHQRIQQEHPDLPQSEINKCISDSWKRLNVADRGYYLERARMERDGVDPSSQSAATSS--QDVPGFRKILPRANYVLLPKSPTAGGDQTEGGDVDVLVDGAPGTPAQDTLVS---PMTLGSEVELTEQCIAIQALSADA---AQNTSICERVTS--LDKTVKKKETGVCYGD----------VAVTVENGED---AGALMPQLKAEATHLVAIIPNQGLVENKVINTASPIMMFPLMSTVKTEPKPSFKLPIKYTRRGRGNCITPGCMFSYVTRHKPPFCPDCGQHLGGKWVPHGK-------RSSSKSSEASSGKECEDSNPTAQRSDDPADLKDTEQTEEQAS---------------------ASRVSSLDKAQDGRSAAAARRVTRKK---RERIKAGSTQQTSDGAAVCKPDETTAVLALGGGQIQIIAREKACSAVQKRRIRAILPAPSQNNSASQPAVMQWITIPPDKVKTDAGIMRA-------VKVSEQHMAGLKPSTLKQLGHMITPAALQ---QKPMTVNSNQYIITDNGVKILSMVPFKKSTGSSLALGLSTARGRGRCKNPACDYVYKNRHKPQQCPTCGCELVNKSSKKSKLTCSEEESAPLLLEPSACLSFSQKEQQRQSTVSLMRSCLQFPESETELQDVFSLIQELNAS---------ENELQESSGWPNFYEPAATHCSLCQQTLYKGEQGSVAGLEDCWLLTERSIRVVTLQLKVCTNLQCLAIHSFTDLYPGLFNVGNKLLVTLDLFFKMRNQIRLGDEPAQAALSIIT--NAQTDGVFTSDQTSRIQELFCSGFWAFECLTLRDYNDMICGICGIAPKLEIAQRSATSVLQLKHVEFTWPDFPAPDEVHVDEFWLTMENEALEQAAFPSSVPITRLDASIIAPFIPPLMRNTTVINTEKNKILNNTHNTGDVAALVHLIHEGRLIPDQLHLHTEEELRDLLEKCAIPAQADTDKADLLASLTSLYTQTQSGLWTADQPEDLLTAGRITKVCPHQVVCGSKYIVRRESARDHLDLLLSSRFWPPVYVADCAQKVALCADVSYPQLAKQMWGENQGCFSDPTAAPQYVSCSELQDQPYSLDLTVTDSNPQLHPLTKSTSRWMVRPDTP--TSTLKDAHYNISLCRELEPYASLSAQICEPNNHKPTQ---VFQNAAYYYLYNRLLDFLSSRDIVNQQITDVLSSCQPGEVLMIRDALYRLGIAHVNTEQEDEEDGGHAHTDGVVELEELMLV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 516, "similar_positions": 390, "identity": "39.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111012-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q02353-1", "uniprot_id": "NDST1_RAT", "id": "Q02353-1", "name": "Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MPALACLRRLCRHLSPQAVLFLLFVFCLFSVFVSAYYLYG-WNRGLEPSADASESDCGDPPPVAPS---RLLPIKP-VQAVAPSRTDPLVLVFVESLYSQLGQEVVAILESSRFKYRTEIAPGKGDMPTLTDKGRGRFALIIYENILKYVNLDAWNRELLDKYCVAYGVGIIGFFKANENSLLSAQLKGFPLFLHSNLGLKDCSINPKSPLLYVTRPSEVEKGVLPGEDWTVFQSNHSTYEPVLLAKTRSSESIPHLGADAGLHAALHATVVQDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAFLTGKRLSLPLDRYILVDIDDIFVGKEGTRMKVEDVKALFDTQNELRTHIPNFTFNLGYSGKFFHTGTDAEDAGDDLLLSYVKEFWWFPHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKQVWNIRVTSTEEYPHLKPARYRRGFIHNGIMVLPRQTCGLFTHTIFYNEYPGGSSELDKIINGGELFLTVLLNPISVFMTHLSNYGNDRLGLYTFKHLVRFLHSWTNLRLQTLPPVQLAQKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKTCDRFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFFP---IPSNTT--------SDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQHQRAHDDPVALKYTFHEVITAGPDASSKLRALQNRCLVPGWYATHIERWLSAFHANQILVLDGKLLRTEPAKVMDTVQKFLGVTSTVDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDLDSRAFLKDYYRDHNIELSKLLYKMG-QTLPTWLREDLQNTR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UHN9-1", "uniprot_id": "NDST1_MOUSE", "id": "Q3UHN9-1", "name": "Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MPALACLRRLCRHLSPQAVLFLLFVFCLFSVFVSAYYLYG-WNRGLEPSADASESDCGDPPPVAPS---RLLPIKP-VQAVAPSRTDPLVLVFVESLYSQLGQEVVAILESSRFKYRTEIAPGKGDMPTLTDKGRGRFALIIYENILKYVNLDAWNRELLDKYCVAYGVGIIGFFKANENSLLSAQLKGFPLFLHSNLGLKDCSINPKSPLLYVTRPSEVEKGVLPGEDWTVFQSNHSTYEPVLLAKTRSSESIPHLGADAGLHAALHATVVQDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAFLTGKRLSLPLDRYILVDIDDIFVGKEGTRMKVEDVKALFDTQNELRTHIPNFTFNLGYSGKFFHTGTDAEDAGDDLLLSYVKEFWWFPHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKQVWGIRVTSTEEYPHLKPARYRRGFIHNGIMVLPRQTCGLFTHTIFYNEYPGGSSELDKIINGGELFLTVLLNPISIFMTHLSNYGNDRLGLYTFKHLVRFLHSWTNLRLQTLPPVQLAQKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKTCDRFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFFP---IPSNTT--------SDFYFEKSANYFDSEVAPRRAAALLPKAKILSILINPADRAYSWYQHQRAHDDPVALKYTFHEVITAGPDASSKLRALQNRCLVPGWYATHIERWLSAFHANQILVLDGKLLRTEPAKVMDTVQKFLGVTSTVDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDLDSRAFLKDYFRDHNIELSKLLYKMG-QTLPTWLREDLQNTR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P52848-1", "uniprot_id": "NDST1_HUMAN", "id": "P52848-1", "name": "Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MPALACLRRLCRHVSPQAVLFLLFIFCLFSVFISAYYLYG-WKRGLEPSADAPEPDCGDPPPVAPS---RLLPLKP-VQAATPSRTDPLVLVFVESLYSQLGQEVVAILESSRFKYRTEIAPGKGDMPTLTDKGRGRFALIIYENILKYVNLDAWNRELLDKYCVAYGVGIIGFFKANENSLLSAQLKGFPLFLHSNLGLKDCSINPKSPLLYVTRPSEVEKGVLPGEDWTVFQSNHSTYEPVLLAKTRSSESIPHLGADAGLHAALHATVVQDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAFLTGKRLSLPLDRYILVDIDDIFVGKEGTRMKVEDVKALFDTQNELRAHIPNFTFNLGYSGKFFHTGTNAEDAGDDLLLSYVKEFWWFPHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHGIPTDMGYAVAPHHSGVYPVHVQLYEAWKQVWSIRVTSTEEYPHLKPARYRRGFIHNGIMVLPRQTCGLFTHTIFYNEYPGGSSELDKIINGGELFLTVLLNPISIFMTHLSNYGNDRLGLYTFKHLVRFLHSWTNLRLQTLPPVQLAQKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKTCDRFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFFP---IPSNTT--------SDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQHQRAHDDPVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKLLRTEPAKVMDMVQKFLGVTNTIDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDLDSRAFLKDYYRDHNIELSKLLYKMG-QTLPTWLREDLQNTR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F0G2-1", "uniprot_id": "E7F0G2_DANRE", "id": "E7F0G2-1", "name": "Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MLCVFRLRRLVRQVPLHTSFLFLFLLCVLSVFLSSYFLYA-VKRELEPSAIGGHAAAGD-LYVTPS---RTLSFMGGTFSSDGSRTDPVVLVFVESQYSHLGQEIVAILESARFRYRTEISPGKGDMPTLMEGRRGRFILIVYENILKYVNMDAWNRELLDRYCIEFGVGIIGFFKANENSLSSAQLKGFPLFLRSNLGLKDCSINPKSPLLHITRAQQVS-GPLPGDDWTVFQSNHSSYEPVVLAKALSADSP------------LHTTVLQDLGLHDGIQRVLFGHNLSFWIHKLVFVDAVSFLTAKRLSLSLERFILVDIDDIFVGKEGTRMKVADVEALLETQNELRRSIPGFTFNLGFSGKFFHAGTDEEDQGDDLLLSYVDEFWWFPHMWSHMQPHRFHNQSVLAEQMILNRRFAEDHSIPTHLGYAVAPHHSGVYPVHIQLYEAWKRVWDIRVTSTEEYPHLKPARFRRGFIHRGIRVLPRQTCGLFTHTIFHEEYPGGPQELEHLIHGGELFLTVLLNPISIFMTHMSNYGNDRLGLFTFKRLLDFLQTWTHLKLQTLPPLQLAEKYFHMFPSDTEPLWQDPCEDKRHKDIWSKEKTCDRFPKLLLIGPQKTGTTALYLFLGMHPDLTSNYPSKETFEEIQFFSGYNYQRGIDWYMEYFP---LPSNSS--------SEYYFEKSANYFDSDVAALRAAALLPRAKIITVLSDPVDRAYAWYQHQRVHGDPVALKYSFHDVITASHNAPVRLQTLQKRCLLPGFYSKHLTRWIQHFHHSQILVVDGQTLKTDPASVLEKIQTFLGLENRVDYHKILAFNPKKGFWCQLLDGGKTKCLGRSKGQRYPDMDTQSQVFLRNYYSDGNIELSKLLYKMG-QTVPGWLRQELLHTR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V3L1-1", "uniprot_id": "NDST_DROME", "id": "Q9V3L1-1", "name": "Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase", "aln": "MTISGGNQHNNNANRKYEKLIKQPQMQFGSSVTGTQTDVDSCRDADADANAVRQDFSNFNKHFGNGHAITDRTMLLRLEDDVTTAAGIVTYKGKSNGNGNGNGNGSIGSISLDFNGSPTSSTSIGIASGSSSNTHLASGGGVGGIGGSEPAGWMCHCCNLIARRCFGINVRRCVLALLAITMVSIFYYTHYVDTGVFNGLIQRDTHPAPIINCRMINSGGKHIRNASPAPDHRSEARLRIDPKVLVFVETTYSGLGRDIAELLVYNRIKYKIEVAG--KSLPVLTNLDKGRYGVIVFENLDKYLNMDKWNRELLDKYCREYSVGIVGFVSPSEETLVGAQLRDFPLFVNTNLRLRDASLNPLSSVLRLTRAGETAWGALPGDDWAVFQHNHSTYEPVEWAQRNTQEYP---ADSVGQVQLPLTTVLQDRGQLDGIQRVLFGSSLRFWLHRLVFLDALSYLSHGQLSLNLERMILVDIDDIFVGEKGTRLRPDDVRALIATQKNIAAMVPGFRFNLGFSGKYYHHGTREENLGDDFLLQNVQEFNWFSHMWKHQQPHLYDNLTLLMAEMHLNYAFAVDHNIPTDSGYSISPHHSGVYPAHELLYMAWKKVWNVKVTSTEEYPHLRPARLRRGFIHRNIMVLPRQTCGLFTHTMYIDRYPGGRDKLDESIQGGELFQTIVYNPINIFMTHMSNYGSDRLALYTFQSVIKFLQCWTNLKLASAPPVQLAEMYFRLHPEEVDPVWGNPCDDVRHKKIWSKTKNCDSLPKFLVIGPQKTGTTALYTFLSMHGSIASNIASPETFEEVQFFNGNNYYRGLDWYMDFFPSESLPNTSSPMPTQLGSPRFMFEKSATYFDGEAVPKRSHALLPHAKIVTILISPAKRAYSWYQHQRSHGDVIANNYSFYQVITASDSAPRALKDLRNRCLNPGKYAQHLEHWLAYYPAQQLHIIDGEQLRLNPIDVMNELQRFLKIQPLLDYSNHLRYDVKKGFYCQAVSEKRNKCLGKSKGRQYPAMDERSAKLLQRYYLNHNTALVKLLKKLGSRPIPQWLKDDLSTGT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : * : : .: *: : :.*:* :::: . * . . : . * . : * ** ******: ** **:::. :* *::*: *:: .:*.* : :**: :*::**: **:*:* *******:** :.***:**....*::* .***:.****:.:** *:*.*:** *.:* :**. :. * ***:**:*** ***:**** *: : : :**:** * ********* .* **:*:***:**:::*: :*** *:* ***********::***:: **.**: **::: :*.* ****:***::* ** *: ***:**. *.** **.***.* *** :.* ::* :* ** ** :*.***. **:::********.* ** ***:**.::**********:*** ******..* *************:: :.**** .:*:. *:***** *:: ***.:****:****.***.*:**: :: **: **:*:* : **:***: **::...: :*:* :**:* ***.**** *.** :**:*:************ **.** .::** .* *****:***.* ** :*:****::** :*..:: . : *****.***.:... *: ****:**::::* .*..***:****** *.* :* :*:*::****. .*. *: *::*** ** *: *: :*: : .*: ::**: *: :* .*:: :* ** : :** : * :: ****:** :. :.****:***::** ** * :*: *: : * * *** *:* :.:* **:::* ", "identical_positions": 413, "similar_positions": 254, "identity": "39.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111012-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LYG4-1", "uniprot_id": "A0ABK0LYG4_RAT", "id": "A0ABK0LYG4-1", "name": "RING finger protein 145", "aln": "MAAKEKLEAVLNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLSNNPLFQYKYLALNMHYVGYILSVVLLTLPRQHLVQLYLYFLTALLLYAGHQISRDYVRSELESAYEGPMYLEPLSMNRFTTALIGQLVVCTLCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPYNLAKSAYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLLFLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPAYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVNGTYRLLEFLVALCVVAYGVSETIFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIKSLPIATKEQLERHNDICAICYQEKQDMKSAVITPCSHFFHAGCLKKWLYVQDTCPLCHCHLKNSSQLPGLGTEPAPQPPVAGAEQNIVLQEGPEPPDHETPPGPGAQEGSGDNSEYINRSSASREGDADPGDGPQIAEGEACPVASA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SWK7-1", "uniprot_id": "RN145_MOUSE", "id": "Q5SWK7-1", "name": "RING finger protein 145", "aln": "MAAKEKLEAVLNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLNNNPLFQYKYLALNMHYVGYILSVVLLTLPRQHLVQLYLYFVTALLLYAGHQISRDYVRSELESAYEGPMYLEPLSMNRFTTALIGQLVVCTLCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPYNLAKSAYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLLFLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPAYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVNGTYRLLEFVVALCVVAYGVSETIFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIKSLPVATQEQLEKHNDICAICY---QDMKSAVITPCSHFFHAGCLKKWLYVQDTCPLCHCHLKNSSQLPGLGTEAAPQPP-AGAEQNIVLQEGPEPPDHESPPGTGTQEGSGDSSEHINRGSASQEGAADAGEGPQIPEGEVCPVESA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96MT1-1", "uniprot_id": "RN145_HUMAN", "id": "Q96MT1-1", "name": "RING finger protein 145", "aln": "MAAKEKLEAVLNVALRVPSIMLLDVLYRWDVSSFFQQIQRSSLSNNPLFQYKYLALNMHYVGYILSVVLLTLPRQHLVQLYLYFLTALLLYAGHQISRDYVRSELEFAYEGPMYLEPLSMNRFTTALIGQLVVCTLCSCVMKTKQIWLFSAHMLPLLARLCLVPLETIVIINKFAMIFTGLEVLYFLGSNLLVPYNLAKSAYRELVQVVEVYGLLALGMSLWNQLVVPVLFMVFWLVLFALQIYSYFSTRDQPASRERLLFLFLTSIAECCSTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDPAMNRGMTEGVTLLILAVQTGLIELQVVHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPAYMAYMICQFFHMDFWLLIIISSSILTSLQVLGTLFIYVLFMVEEFRKEPVENMDDVIYYVNGTYRLLEFLVALCVVAYGVSETIFGEWTVMGSMIIFIHSYYNVWLRAQLGWKSFLLRRDAVNKIKSLPIATKEQLEKHNDICAICY---QDMKSAVITPCSHFFHAGCLKKWLYVQETCPLCHCHLKNSSQLPGLGTEPVLQPH-AGAEQNVMFQEGTEPPGQEHTPGTRIQEGSRDNNEYIARRPDNQEGAFDPKEYPHSAKDEAHPVESA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3APB9-1", "uniprot_id": "A0A8M3APB9_DANRE", "id": "A0A8M3APB9-1", "name": "RING finger protein 145", "aln": "MAVKERVEAVLNVGLRVPSIMLLEVLYRWDVSSFFQKIQRSSLNNNPLFQYKYLALYLHYVGYILSLVLLTLPRQHLVQLYLYVLTALLLFAGHQISRDYVRSELESGYEGPLYLEPLSINRFTTALLCQLVVCTLCSCVMQTKRIWLFSAHLLPLVARLCLVPLETIVFVNRFAMIFTGLEVIYFLASNLLVPFNLAKTAYRELAQVVEVYGLLALGMSLWNQLVLPVLFMCFWLVLFALQIYTYFSTRDQPTSRERLLFLFLTSIAECCCTPYSLLGLVFTVSFVALGVLTLCKFYLQGYRAFMNDNTMHRGMTEGITLLILAVQTGLIELQVIHRAFLLSIILFIVVASILQSMLEIADPIVLALGASRDKSLWKHFRAVSLCLFLLVFPAYMSYMICQFFHMDFWLLIIISSSILTSLQVLGTLLIYVLFMVEELRKAPVENMDDVIYWVNGTYRLLEFLVALCVVAYGVSETVFGEWTVMGSTIVLIHSYYNVWLRAQLGWQSFLLRRDAVNKIKSLPTASLQQLQQHNDICSICY---QDMTSAVITPCSHLFHAGCLKKWLYVQETCPLCHNQLKGSSQLGSSSQDVPPQDTPAQPEED---QDPSEPADSES----NLQDLRQDDSSTRAPASELRARLKQQTDPPACSSS--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.**::******.*********:************:******.************ :********:****************.:*****:*************** .****:******:*******: ************:**:*******:***:************::*:**********:***.******:****:*****.********************:***** ***********:********:*****************.************************************ :*:******:****************:************************************************************:*******************************:*********:** **********:**********:*************:********* *::***************:**************** *: :**::*****:*** ***.*********:*************:****** :**.**** . . : * * .*:: *: .**.. * *: *... . : : : * ... ", "identical_positions": 529, "similar_positions": 76, "identity": "79.31%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111013-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2H4-1", "uniprot_id": "LGR4_RAT", "id": "Q9Z2H4-1", "name": "Leucine-rich repeat-containing G protein-coupled receptor 4", "aln": "-------------MPGPLRLLCFFALGLLGSAGPSGAAPPLCAAPCSCDGDR-------------------------------------------------------------------------------------------------------------RVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKSFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLRTVPSEAIHGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVRPLSNLPTLQALTLALNNISSIPDFAFTNLSSLVVLHLHNNKIKSLSQHCFDGLDNLETLDLNYNNLDEFPQAIKALPSLKELGFHSNSISVIPDGAFGGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASLVQWFPNLTGTVHLESLTLTGTKISSIPDDLCQNQKMLRTLDLSYNNIRDLP------------------------SFNGCRALEEISLQRNQISLIKENTFQGLTSLRILDLSRNLIREIHSGAFAKLGTITNLDVSFNELTSFPTEGLNGLNQLKLVGNFKLKDALAARDFANLRSLSVPYAYQCCAFWGCDSYANLN-----------------------------------------------------------------------TEDNSPQEHSVTKEKGATDAANVTSTAENEEHSQIIIHCTPSTGAFKPCEYLLGSWMIRLTVWFIFLVALLFNLLVILTVFAS-CSSLPASKLFIGLISVSNLLMGIYTGILTFLDAVSWGRFAEFGIWWETGSGCKVAGSLAVFSSESAVFLLTLAAVERSVFAKDLMKHG--------KSSHLRQFQVAALLALLGAAVAGCFPLFHGGQYSASPLCLPFPTGETPS-LGFTVTLVLLNSLAFLLMAIIYTKLYCNLEKEDLSENSQSSVIKHVAWLIFTNCIFFCPVAFFSFAPLITAIS---ISPEIMKSVTLIFFPLPACLNPVLYVFFNPKFKEDWKLLKRR-------VTRKHGSVSVSISSQ----GGCGEQD----FYYDCGMYSHLQGN----------------------------------------------------------------LTVCDCCESFLLTKPVS---------CKHLIKSHSCPVLT--AASCQRPEAYWSDCGTQSAHSDYADEEDSFVS---DSSDQVQACGRACFYQSRGFP------------------------------------------LVRYAYNLQRVRD-------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2ARI4-1", "uniprot_id": "LGR4_MOUSE", "id": "A2ARI4-1", "name": "Leucine-rich repeat-containing G protein-coupled receptor 4", "aln": "-------------MPGPLRLLCFFALGLLGSAGPSGAAPPLCAAPCSCDGDR-------------------------------------------------------------------------------------------------------------RVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNILTEVPVRPLSNLPTLQALTLALNNISSIPDFAFTNLSSLVVLHLHNNKIKSLSQHCFDGLDNLETLDLNYNNLDEFPQAIKALPSLKELGFHSNSISVIPDGAFAGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASLVQWFPNLAGTVHLESLTLTGTKISSIPDDLCQNQKMLRTLDLSYNDIRDLP------------------------SFNGCRALEEISLQRNQISLIKETTFQGLTSLRILDLSRNLIREIHSGAFAKLGTITNLDVSFNELTSFPTEGLNGLNQLKLVGNFQLKDALAARDFANLRSLSVPYAYQCCAFWGCDSYANLN-----------------------------------------------------------------------TEDNSPQDHSVTKEKGATDAANATSTAESEEHSQIIIHCTPSTGAFKPCEYLLGSWMIRLTVWFIFLVALLFNLLVILTVFAS-CSSLPASKLFIGLISVSNLLMGIYTGILTFLDAVSWGRFAEFGIWWETGSGCKVAGSLAVFSSESAVFLLTLAAVERSVFAKDVMKNG--------KSSHLRQFQVAALVALLGAAIAGCFPLFHGGQYSASPLCLPFPTGETPS-LGFTVTLVLLNSLAFLLMAIIYTKLYCNLEKEDPSENSQSSMIKHVAWLIFTNCIFFCPVAFFSFAPLITAIS---ISPEIMKSVTLIFFPLPACLNPVLYVFFNPKFKDDWKLLKRR-------VTRKHGSVSVSISSQ----GGCGEQD----FYYDCGMYSHLQGN----------------------------------------------------------------LTVCDCCESFLLTKPVS---------CKHLIKSHSCPVLT--VASCQRPEAYWSDCGTQSAHSDYADEEDSFVS---DSSDQVQACGRACFYQSRGFP------------------------------------------LVRYAYNLPRVRD-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BXB1-1", "uniprot_id": "LGR4_HUMAN", "id": "Q9BXB1-1", "name": "Leucine-rich repeat-containing G protein-coupled receptor 4", "aln": "-------------MPGPLGLLCFLALGLLGSAGPSGAAPPLCAAPCSCDGDR-------------------------------------------------------------------------------------------------------------RVDCSGKGLTAVPEGLSAFTQALDISMNNITQLPEDAFKNFPFLEELQLAGNDLSFIHPKALSGLKELKVLTLQNNQLKTVPSEAIRGLSALQSLRLDANHITSVPEDSFEGLVQLRHLWLDDNSLTEVPVHPLSNLPTLQALTLALNKISSIPDFAFTNLSSLVVLHLHNNKIRSLSQHCFDGLDNLETLDLNYNNLGEFPQAIKALPSLKELGFHSNSISVIPDGAFDGNPLLRTIHLYDNPLSFVGNSAFHNLSDLHSLVIRGASMVQQFPNLTGTVHLESLTLTGTKISSIPNNLCQEQKMLRTLDLSYNNIRDLP------------------------SFNGCHALEEISLQRNQIYQIKEGTFQGLISLRILDLSRNLIHEIHSRAFATLGPITNLDVSFNELTSFPTEGLNGLNQLKLVGNFKLKEALAAKDFVNLRSLSVPYAYQCCAFWGCDSYANLN-----------------------------------------------------------------------TEDNSLQDHSVAQEKGTADAANVTSTLENEEHSQIIIHCTPSTGAFKPCEYLLGSWMIRLTVWFIFLVALFFNLLVILTTFAS-CTSLPSSKLFIGLISVSNLFMGIYTGILTFLDAVSWGRFAEFGIWWETGSGCKVAGFLAVFSSESAIFLLMLATVERSLSAKDIMKNG--------KSNHLKQFRVAALLAFLGATVAGCFPLFHRGEYSASPLCLPFPTGETPS-LGFTVTLVLLNSLAFLLMAVIYTKLYCNLEKEDLSENSQSSMIKHVAWLIFTNCIFFCPVAFFSFAPLITAIS---ISPEIMKSVTLIFFPLPACLNPVLYVFFNPKFKEDWKLLKRR-------VTKKSGSVSVSISSQ----GGCLEQD----FYYDCGMYSHLQGN----------------------------------------------------------------LTVCDCCESFLLTKPVS---------CKHLIKSHSCPALA--VASCQRPEGYWSDCGTQSAHSDYADEEDSFVS---DSSDQVQACGRACFYQSRGFP------------------------------------------LVRYAYNLPRVKD-------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FE13-1", "uniprot_id": "LGR4_DANRE", "id": "E7FE13-1", "name": "Leucine-rich repeat-containing G protein-coupled receptor 4", "aln": "----------MALLAVRMLVLGLCVGGQAAAAGEGQSTPATCSPLCRCDEDG-------------------------------------------------------------------------------------------------------------GADCSGRGLTSVPTGLSAFTYYLDISMNNITELPANVFRNLPYLEELRLAGNDLAFIHPEALSGLHQLKVLMLQNNQLKTVPSAALKNLNALQSLRLDANHITSVPEDSFEGLQQLRHLWLDDNSLTEVPISPLQHQSNLQALTLALNRITHIPDNAFANLSSLVVLHLHNNRIQEIGKNCFNGLDNLETLDLNFNNLKIFPEAIQMLPKLKELGFHSNNIASIPEGAFCRNSLLRTIHLFDNPLSFVGTTAFQNLSDLHSLMLRGASMMQDFPSLTGTINLESLTLTGTKIRSIPADLCEDLTVLRTVDLSYNDIEDLP------------------------SFQGCVRLQDINLQHNQIKQIDRGTFQGMTSLRVLDLSRNQIKFIHRDAFLSLSALTNLDLSLNSLASVPTAGLSALNQLKLTGNMELRNGLMSKTLPKLRSITVPYAYQCCAFVAYDSAVNPA-----------------------------------------------------------------------EDD---------------ERRNAFGGEEDMERIPMVMHCSPLPGAFKPCEHLLGSWMIRLTVWFICLVALLFNCLVLAATFSPRTSSLSPSRFLVALLASANLLTGVYVAALTLLDTVTWGSFAEYGVWWETGAGCQVVGFLAVFSSEWAVLLLALAAVERCLAVRALMGKAGALRSRGERRERRRRFAIAALLLGLVSVAAACLSLYHG-SAMGSPLCLPFSEGSSPG-LGFTVALVLMNTLAYLLSAVVYTRLYCRLGRAQLADPEQAGSVRHIAWLIFTNCIFFCPVAAFSFAPLLAGTSNAVGGPEMAKSVTLIFFPLSACLNPVLYVCFSPSFRYDWLHLRGRG------RTGGCGRLVAKTVTKGTVAGGSPVSDDGEGLSSDCGMYTKLHGDS---------------------------------------------------------------RGMCEHCDAALHIRTSSSSGSSSSSACRHLVKSHSCPALMGNVPQCLSSEGYWPDTGTLSAQSEYGDEGDSFVS---DSSEQVQACGRACFCQSRGLP------------------------------------------LVHYSYNIPRMTD-------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7KTA0-1", "uniprot_id": "Q7KTA0_DROME", "id": "Q7KTA0-1", "name": "", "aln": "MAARCRWSWRLALCPLLLQLLLQLLLLPPSAMGHDETKENPAPDMQNSQEQEPYVHLQHLQQQQQQNPQTVQQLSQITVNRTSKSASVTPTGIRENVMLPSADPEKEAQILYEKSLQEYHGSQLSTASTATDVIAGKRTLHSICERWLQKHCHCTGSLEVLRLSCRGIGILAVPVNLPNEVVVLDLGNNNLTKLEANSFFMAPNLEELTLSDNSIINMDPNAFYGLAKLKRLSLQNCGLKSLPPQSFQGLAQLTSLQLNGNALVSLDGDCLGHLQKLRTLRLEGNLFYRIPTNALAGLRTLEALNLGSNLLTIINDEDFPRMPNLIVLLLKRNQIMKISAGALKNLTALKVLELDDNLISSLPEGLSKLSQLQELSITSNRLRWINDTELPRS--MQMLDMRANPLSTISPGAFRGMSKLRKLILSDVRTLRSFPELEACHALEILKLDRAGIQEVPANLCRQTPRLKSLELKTNSLKRIPNLSSCRDLRLLDLSSNQIEKIQGKPFNGLKQLNDLLLSYNRIKALPQDAFQGIPKLQLLDLEGNEISYIHKEAFSGFTALEDLNLGNNIFPELPESGLRALLHLKTFNNPKLREFPPPDTFPRIQTLILSYAYHCCAFLPLVAMSSQKKTSQVQEAVLFPSDAEFDMTLWNNSMMNIWPQMHNLSKQLGASMHDPWETAINFNEEQLQTQTGGQIATSYMEEYFEEHDVSGPATGYGFGTGLFSGMSTEDFQPGSVQCLPMPGPFLPCADLFDWWTLRCGVWVVFLLSLLGNGTVVFVLLCS-RSKMDVPRFLVCNLAAADFFMGIYLGILAIVDAATLGEFRMFAIPWQMSVLCQLSGFLAVLSSELSVYTLAVITLERNYAITHAIHLN--------KRLSLKQAGYIMSVGWVFALIMALMPLVGVSDYRKFAVCLPFETTTGPASLTYVISLMFINGCAFLTLMGCYLKMYWAIRGSQAWNTNDSRIAKRMALLVFTDFLCWSPIAFFSITAIFGLQL---ISLEQAKIFTVFVLPLNSCCNPFLYAIMTKQFKKDCVTLCKHFEESRVVGGGGPGGRGAVARTKRGDLPPPLLPAAAVAHPPGCRCLRMLPSEMPNWHKMEQTPSMWQRLRTFCCGENRRRRKQRRQPQQRRQRAYTAAAANPYQYQFAELRQQRQNRASSISSENFCSSRSSS---WRHGPPSSAPVPPGNCSMPLKMLEPHAHPHGHGRRRHSAWLITRKTSQDSNLSSSRNDSSASATTASTSTFRLSRSSAGSSTPLPSIIAHNGKAQLDAVKPRLVRQEAVQEEEDSSPPRLGVRFLPTIPSAADSSVVMEDGDSANTGVASFLGMPLPGASSGFLIAPTTAATTSPPPVVLQPAKPPPDPNDAPL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :* .: * . : .. .: : .* * *: :** .*. . **:. **:*:* : * * **** *:.*.: :.*:*: ** :** * *** *:::*. :::.* * **:*:.* :.*: *.: * :** * *:.* : .:* .* .*:**.*. * :: * * *..:..*:** *:.*:* .:. .:..* *:.*:*: * : :*:.:. *..*:**.: ** : * : : . :: :.: **** :. **:.:*.*:.*:: .. :: **.* . ** *.* : * .:* :**.: *::::*. *.:. :* .*:* *::: *. *:* : . :***: .*::***. * * ** ** : .: :*::. * :...* ** .* :** .* :*:: . : .:::: :.***:**** : . :: . . . : ::* * .*.* ** *:. * :* **.: *::*: * *: . :.. :.: .:::: :: :::: *:* . *:::*:.: * * :.: *: . *:: * ***:*** :: * : ::** : : :: : : : . :.* . .:**** *. * :.::*:::* *:* * ::* : : : .:: :::* *:**: : :.*:* **::.:: . * * .*::.:** :* **.**. :. .*: * * : * . :: .* * .: . .: :. * . : . .*. ...: : : .: ..: * *** .. :.. : * **. . *:: .: * ", "identical_positions": 218, "similar_positions": 332, "identity": "15.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111013-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P58686-1", "uniprot_id": "BBLN_MOUSE", "id": "P58686-1", "name": "Bublin coiled-coil protein", "aln": "MSGPNGDLGMPVDAGTEGENDSFGEAEYAAINSMLDQINSCLDHLEEKNDHLHARLQELLESNRQTRLEFQQQLG--------------EAPGDASP--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BUW7-1", "uniprot_id": "BBLN_HUMAN", "id": "Q9BUW7-1", "name": "Bublin coiled-coil protein", "aln": "MSGPNGDLGMPVEAGAEGEEDGFGEAEYAAINSMLDQINSCLDHLEEKNDHLHARLQELLESNRQTRLEFQQQLG--------------EAPSDASP--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QHR5-1", "uniprot_id": "F1QHR5_DANRE", "id": "F1QHR5-1", "name": "", "aln": "MSGPNGDPDISAEGIIE-DEDEFNEEEYAAIDSMLDQINSCLDDIEERNDALNGKLQELLESNRAARRDFRQQITDHADLPPPANDDEDEQSRDAQKKD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "******* .:..:. * ::* *.* *****:***********.:**:** *:.:********* :* :*:**: * . **. ", "identical_positions": 48, "similar_positions": 22, "identity": "48.48%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111017-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TSY2-1", "uniprot_id": "LHPL4_RAT", "id": "Q7TSY2-1", "name": "LHFPL tetraspan subfamily member 4 protein", "aln": "---MLPSQEASKLYHEHYMRNSRAIGVLWAIFTICFAIINVVVFIQPYWVGDSVSTPKPGYFGLFHYCVGSGLAGRELTCRGSFTDFSTIPSSAFKAAAFFVLLSMVLILGCITCFALFFFCNTATVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRDMCGAKTGKYSLGDCSVRWAYILAIIGILNALILSFLAFVLGNRQTDLLQEELKQE-------NKDFVGTTVSSVLRPGGDVSGWGVLPCPVAHTQGP------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5U4E0-1", "uniprot_id": "LHPL4_MOUSE", "id": "Q5U4E0-1", "name": "LHFPL tetraspan subfamily member 4 protein", "aln": "---MLPSQEASKLYHEHYMRNSRAIGVLWAIFTICFAIINVVVFIQPYWVGDSVSTPKPGYFGLFHYCVGSGLAGRELTCRGSFTDFSTIPSSAFKAAAFFVLLSMVLILGCITCFALFFFCNTATVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRDMCGAKTGKYSLGDCSVRWAYILAIIGILNALILSFLAFVLGNRQTDLLQEELKQE-------NKDFVGTTVSSVLRPGGDVSGWGVLPCPVAHTQGP------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z7J7-1", "uniprot_id": "LHPL4_HUMAN", "id": "Q7Z7J7-1", "name": "LHFPL tetraspan subfamily member 4 protein", "aln": "---MLPSQEASKLYHEHYMRNSRAIGVLWAIFTICFAIINVVVFIQPYWVGDSVSTPKPGYFGLFHYCVGSGLAGRELTCRGSFTDFSTIPSSAFKAAAFFVLLSMVLILGCITCFSLFFFCNTATVYKICAWMQLLAALCLVLGCMIFPDGWDAETIRDMCGAKTGKYSLGDCSVRWAYILAIIGILNALILSFLAFVLGNRQTDLLQEELKPE-------NKDFVGSTVSSVLRPGGDVSGWGVLPCPVAHSQGP------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8RTK1-1", "uniprot_id": "A0A2R8RTK1_DANRE", "id": "A0A2R8RTK1-1", "name": "", "aln": "---MLPSQEASKIYHDNYMRNSRAIGVLWAIFTICFATINVVVFIQPYWIGDSVSTPHAGYFGLFHYCVGDGNSNRELICQGTFSDFSSIPSGAFKAASFFVLLSMVLILSCIACMALFFFCNTATVYKTCAWMQLLCAVCLVLGCLIFPDGWDAEVIRDMCGEETGKYTLGNCSVRWAYILAIIGILDALILSFLAFVLGNRQNDFMHDEIKAE-------NKD--------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W068-1", "uniprot_id": "Q9W068_DROME", "id": "Q9W068-1", "name": "", "aln": "MGTKIEYVDTTHLYASKYIRNSKAIGVLWAIFTICYAIIGIVAFVTPEWIGDPDND-GAGRLGLWQQCQRDEIFDN---CRRRWESIFEVPTFSFQLATFFMLGAIALALLTIFFLVCLLFMKSTRVFHLCGWMQIISAICMIVACAAFPFGWNSDDFRKICGPEANRFELGLCGIRWAYPLAIIGCIDGVVLATLAFILATRHVRLQPDPIYQNSLYKGEINNAYLTDAISLAGSRKSNPRITGLNLQPILLVAPPNEDSISQFSRYH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :::::* .:*:***:************:* *.:*.*: * *:**. . .* :**:: * . .. *: : .: :*: :*: *:**:* ::.* * * : ::* ::: *:: *.***::.*:*:::.* ** **::: :*.:** ::.:: ** *.:**** ***** ::.::*: ***:*..*: : : : : *: ", "identical_positions": 74, "similar_positions": 83, "identity": "27.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111019-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6Q0N2-1", "uniprot_id": "FA89A_RAT", "id": "Q6Q0N2-1", "name": "Protein FAM89A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGA----GSAG--------------------MARGLRVDGLPPLPKSLS-----------------GLLHSAAGG-AAGGWRHLERLYAQKSRIQDELNRGGAGGGGARAAGMRTKPPN------------------LDAALALLRKEMVGLRQLDMTLLCQLYGLYESIQEYKGACQ---AASSLDCNYALENG---FFDDDED-FQEQGSLRDGQGRGSPGDPSL---------------PLTHLSSSDWILESI----------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q14BJ1-1", "uniprot_id": "FA89A_MOUSE", "id": "Q14BJ1-1", "name": "Protein FAM89A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGT----GSAG--------------------MARGLRVDGLPPLPKSLS-----------------GLLHSAAGG-AAGGWRHLERLYAQKSRIQDELNRGGAGGGGARAAGMRTKPPN------------------LDAALALLRKEMVGLRQLDMSLLCQLYSLYESIQEYKGACQ---AASSLDCTYALENG---FFDDEED-FQEQGSLQDGQHHGSPRDQS----------------PLTHLSSSDWILESI----------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96GI7-1", "uniprot_id": "FA89A_HUMAN", "id": "Q96GI7-1", "name": "Protein FAM89A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSGARAAPGAAGNG------------------AVRGLRVDGLPPLPKSLS-----------------GLLHSASGGGASGGWRHLERLYAQKSRIQDELSRGGPGGGGARAAALPAKPPN------------------LDAALALLRKEMVGLRQLDMSLLCQLYSLYESIQEYKGACQ---AASSPDCTYALENG---FFDEEEEYFQEQNSLHDRRDRGPPRDLSL---------------PVSSLSSSDWILESI----------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A8F3-1", "uniprot_id": "A0AB13A8F3_DANRE", "id": "A0AB13A8F3-1", "name": "Protein FAM89A", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNDKVG-NGAAG---------------------GVLACIEGLPPLPKSLS-----------------GLLNSSGGS-----WRDMERMYVKKTMIQDDLSRGRNNADNLLAN----KPAN------------------LDAALALLRKEMVGLRQQDMSLLCQLWSLHESIQEYKGSCQDLSAVSSADGPYGMENG---YFDEDEEYYTESAVTPAETPDGN--DTS----------------PKNGTSKDSWIHDSFHITI------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ACA5YM07-1", "uniprot_id": "A0ACA5YM07_DROME", "id": "A0ACA5YM07-1", "name": "", "aln": "MATTAAGSAATTTNTMVVKRPGPPVPPRPKAAAQLANGAGAPPIIQKKPTFVSQLSAVGRTLVYKSPTVNLPKKQAQTQTPTTAVPTPPVKPLKLRKAPDVPTAKPRDSMTSVVTVNRHNSISVIGSTPQTTPRKDTRLSLGKVDFERAGLQPASQPLPRPRKIVQVPVATLDVEDIPVVAPSPSSNGLFRRSKTTLDGSQKDSASSPHNGGGFLSGRTVEIKNNLKNAAERLFSEIIINQSQKQAATDTTIITKHEALKQESDVLAIQSSGNCMRINVNGGQTSTMKSSISVGNTPQKKQAFHEMLISELAAMRNKSCSLEQLPTAKSPPPTTSTPKSVASRRRYNSIDDADTEDVDADNVEDADGDVDEEDTLTYAVNKSLKENIGKEGSSSRKRCPSGCSTDSSPYGTERSQRIRTSDWIEVGDNGTAVTLTSCHISLEDSGMEDEERLDDMSSGVGDSWDSVKEAESEKRSRNGKRGNSACELPPLPKSLIGFNKLLCSDSGLLSDVEGNNNSSDGSRKPNDNLAVETQDTKEHATDKSLPSSPNGNTSIPPMLVAKSEAKSPSLSAKGNPQAVEAGSTLDAQIATLRKEMNGLRQLDLSLLSQLWVLNESIQEFRALIED-QENEDEDDEVEVEVG---NELDEEGNSRVSSSIESVRLEGGADGTSKH----------LGTIPKVITTQPKVLRDSLATASKDQKPVPRMRSA-------PPPPPPAVLQSLSLERKPPAPSRPTXCYLSDFLAGVRMVMCKAIVSDVPASSASASLGGDGAPLGRDAQSCLGNQTGQVLQA-------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLJ5-1", "uniprot_id": "Q9VLJ5_DROME", "id": "Q9VLJ5-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMENSSNDAQPHLTGLPPLPKSLSAATAAPVAIGPHPRTASPASSVNALTVAAG------------------ELYLGPSTSSSAASRNRSYN-----------------GHGHSQRHGSLSSTQESLSDRESVHSRASSTHSAGAVHTPTNSSSSTGATSST------------------IDNQLAILRREMYGLRQLDLSLLSQLWALNESIQGFRVFLQEQDALSPPSRSRTPSDANSLSSDEEDDGSYAPVALPKMTDTAGAGSAGVVNSRAMASPAASGGLPTKLATGSTTSHASTSSTSGASGSSSAASSMGKHQQVQQQQQQQSQSANHYHQRPAPPPAPPAQHKAHPQLPRILQQRMRQAPPPPPPTRQKAGGGGGGGASTSSSNHSISSVTQPHPHSHQHPQHTHHSRPV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. :. .. :* * :* . :. . .. . . . .. :* :* **:** **** *::**.**: * **** :: : . . . . ::: . . . * : * ", "identical_positions": 25, "similar_positions": 40, "identity": "3.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111020-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CCG1-1", "uniprot_id": "ZC21C_MOUSE", "id": "Q8CCG1-1", "name": "Zinc finger C2HC domain-containing protein 1C", "aln": "MAGLQ-LAPHLPVGVMFPHNKTEAPGLHSAKHDPYEQSDSSQRPSMGHLRNSFQSKLWSNTEMEQEDEVSTRPKRNVCTKARRHSCPHSAGIRQQGSGNNAQGQGKGLFYLSSPTPRYPKANDQDFIPFRRKRVGVDRAYPLKPMVHRKSHSTSDAGADGDQNGYPRLPDSSEFSDNSFGLRS----WVNSSLLASVQAEKVVAELHRTEWTQIQRLEAAGESLQKEIRRKEILLQEKLKKTEEGLRRMQKEKKQAIFQ---EDRELQRMVLPRRRVRDGDHDTPHKPCLSPEFR--SEVFSRNRGEDQTCDQAQENPSPRQLSDYELQKLKRERLMASNSKIRDQDAG----PSADAFFQPAEELGSTLQESSR----SGTPGSSGSSSSTEEPE-LAKCSHCGRSFLSLRLQRHSTVCGKMQGSKRKVFDSSRARAKGTELEQYLNWRGPATAKAETPPPPRKSTWRQKHESFIRTLRHARQVQQVIARGGNPSDLPSILPADNPDYVQCPHCSRHFAPKVAERHIPKCKTIKNRPPPPRRHDS---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53FD0-1", "uniprot_id": "ZC21C_HUMAN", "id": "Q53FD0-1", "name": "Zinc finger C2HC domain-containing protein 1C", "aln": "MAGLQRLASHLPVGVMLPHNTTEAPGPHSAKQDSYEQGDSSQQSLKGHLRNNFQKQLLSNKELIL-DKVYTHPKWNTQTKARSYSYPHCTGISQQDPESDSQGQGNGLFYSSGPQSWYPKANNQDFIPFTKKRVGVDRAFPLKPMVHRKSCSTGEAGTDGDHNVYPRPPEPREFSSRNFGVRNQGNFSVVGTVLAATQAEKAVANFDRTEWVQIRRLEAAGESLEEEIRRKQILLRGKLKKTEEELRRIQTQKEQAKEN---ENGELQKIILPRSRVKGNKSNTMYKPIFSPEFEF-EEEFSRDRREDETWGRSQQNSGPFQFSDYRIQRLKRERLVASNNKIRDPVSE----PSVEKFSPPSETPVGALQGSARNSSLSMAPDSSGSSGSIEEPQ-LGECSHCGRKFLSFRLERHSNICSRMRGSKRKVFDSSRARAKGTELEQYLNWKGPASAKAE---PPQKSNWR--------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TBJ1-1", "uniprot_id": "A0AB32TBJ1_DANRE", "id": "A0AB32TBJ1-1", "name": "", "aln": "-----------------MSTTHRRPSPSGAAYASYIN-----MQMLPHHHHHFQEKETVSLKLPYLQDTSRHHNYKLDIVENQLRKMSFARERHHPES------------IHKTQPIYEEEQNQ-YVPSRRE---SDRLFPLKPVLHKRAYSLSNIPK---PDHYPTLAEQAALRHQQKMVRK-----------LDAQDQHIPARTS----SHEQKSSETHTRLSKEIHSKEMMLQQKIFRAEETVRRVQRERNKRFFEKQLDDRLYSDWYEGTGRYENERDDMERWEIRDAKQHTRGQLLTSERVKDHVPREWDDTTKDWGLEKINIRREREMTLNNHVRRRRETDREDLRKSTRRDGSQRRHDRGADEDALGQLSYRRLNAKSAGRDDGEENAELLIPCSVCQRCFAPERLETHMRVCEKKR-PQRKVFDMSKYRARGTELEEFMKTNSRSRTPER-----KKNMWRQKHEAFIQTMRQGR---------SSTSQQPNSTSGLHQEYITCPHCGRKFAPGPAERHVPKCQTIKSRPAPPKQPHNSATRRRTTH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . *. .* .* : * :: **.: . :: :.. : : : . : :: . . * : ::* ::* :: ** :****::*::: * .: : ** .: : .. :*. .* :: *. : :: . : *.:**: *:::*: *: ::** :**:* :::: : :: . * .. : ..: . : :: :* :*.. . ::.. :.. .::: :. * : *: .: . . : .: . *:* ... *:.: * ** * * * . **: * :* : : .:***** *: **:*****:::: .. : : . :*. ** ", "identical_positions": 67, "similar_positions": 143, "identity": "12.07%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111020-10", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Y6S9-1", "uniprot_id": "RPKL1_HUMAN", "id": "Q9Y6S9-1", "name": "Ribosomal protein S6 kinase-like 1", "aln": "MSLVACECLPSPGLEPEPCSRARSQAHVYLEQIRNRVALGVPDMTKRDYLVDAATQIRLALERDVSEDYEAAFNHYQNGVDVLLRGIHVDPNKERREAVKLKITKYLRRAEEIFNCHLQRPLSSGASPSAGFSSLRLRPIRTLSSAVEQLRGCRVVGVIEKVQLVQDPATGGTFVVKSLPRCHMVSRERLTIIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWS--------------------------------------HLLSQAHSRHS--------GLSSGSTQERMKAQLNPHLNLLTPARLPSG------HAPGQDRIAL-----------EPPRTSPNLLL--------------AGEAPSTRPQREAEGEPTAR-------------TSTSGSSDLP----------------------------KAPGGHLHLQARRAGQ--------------NSDAGPPRGLTWVPEGAGPVLGGCGRGMDQ-------------------SCLSADGAGRGCG-----------------------------RATWSVR---EEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEVEPQCCGEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQLQLPEWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKLVG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R2S1-1", "uniprot_id": "RPKL1_MOUSE", "id": "Q8R2S1-1", "name": "Ribosomal protein S6 kinase-like 1", "aln": "MSLVACECPPGPGLEPEPCSRARSQACMYLEQIRNRVATGTADVTKRDYLVDAATQIHLALERDVSEDYEAAFNHYQNGVDVLLRGVHVDPNKERREAVKLKITKYLRRAEEIFNCHLQRTLGSGASPNTGFSSLRLRPIRTLSSALEQLKGCRVVGIIKKVQVVQDPATGGTFIVKSLPRCHMVSRERLTIIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWS--------------------------------------HLLSQDHFQYS--------GLNSGSVQEKSQAQLSTRLSLMTPAELTPG------HTLRQNRIPM-----------EPPRTSQSLP-------------------PALQLQKEADAEPSSR-------------PSAVFSSDPT----------------------------EAPCGHSHSQVRRAGQ--------------SSNPAPTQRLHWVREGADRVLGAYGRGRGR-------------------NPPSANRASLGSG-----------------------------RAAWSLR---EGQVKQWAAEMLLALEALHQQGVLCRDLNPQNLLLDQAGHIQLTYFGQWSEVEPRCSQEAVDCLYSAPEVGGISELTEACDWWSYGSLLYELLTGMALSQSHPSGFQAHTQLQLPEWLSHPAASLLTELLQFEPQRRLGAGGGGTSRLKSHPFFSTIQWSRLMG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PCX1-1", "uniprot_id": "A0A8M9PCX1_DANRE", "id": "A0A8M9PCX1-1", "name": "", "aln": "-------------------------------------------MAKKDYLLDAAQQIRMALDREVNEDYEAAFSYYKNGVDLLLNGVQVDPNKERREAVKRKTTQYLKRAEEIFISYLQDNISKGSTHLGGYSSLRFRSIRHLSSPVENLAMCKVTGVIDKVLTVESLINKETFIVKSLPKSSWESRERSTIIPQGVPFMVKLLKYYVSEDTVFLHLEHLQGGRLFSRLHRVRSEAIREYPECFSPNQHKIYLKNSYTLPVLRQNTYLNEDYGRTSPPANHRLENCNPRSYCEDVGCQQTGSPSVFASDGLPSVGVPNGLNSLPQDNAPLPIHPCVIVDTRDPLDVTSDLLGNDVRIERIDSCVDLSKAWGALEPAQDCRGFTGSNSDILGFRIAAQITPSTLFGANAQPILCSTVNVLPQRVRIIPNASTKHQAHDGFPHEHNSPHRRPSGQQFVTEFHKVSSHRYSFECTPQNQDGFTLEFTNMTSRGNSGDLGKQDNCQFFSHSFTQPEVSMISCPSASTTNSACWSETYLEAGHRVNVAGLESKPQINTKNVGAKAKWGRRGLPEDEVRLWGAQILLALESLHEQGIVCQDLNPRNILLRSSGEACLTYFGQWTEVQPEINPKAMEEMYCAPEIGGVSKVTEACDWWSFGALLYELLTGMPLWQCHPAGVHPHTPLHIPEFLSTAATSLLTELLQFDACYRLGSGGGGVSDIKCHPFFSAVPWLKLSSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*:***:*** **::**:*:*.*******.:*:****:**.*::************ * *:**:****** .:** :..*:: *:****:*.** ***.:*:* *:*.*:*.** *:. . **:*****:. **** ****:***:*.***:*:****::******:*** *:* *.: : : * . .. * * .* . .:::. *.. :: *:. .: :* .: .* : . ::. . . :. .*: .:: * * : * :** . : * . :. * :. . . . . .: . **. :. .. :* *. * * :*: *.*::*:***:**:**::*:**:* *:** .:*. *******:**:*. :*:: :*.***:**:*::********:*:*********.* *.**:*.:.** *::**:** .*:*********:. *** * **.* :*.*****:: * :* . ", "identical_positions": 226, "similar_positions": 163, "identity": "30.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111020-12", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RYM0-1", "uniprot_id": "ANGE1_RAT", "id": "B2RYM0-1", "name": "RNA 2',3'-cyclic phosphatase ANGEL1", "aln": "MIASCLYYLLLPAARLFRFLSDAFFT--------------------CRKNALLAKS--SSPQVEGNFAMAPRGPDQEECEGLLQQWREEGWNQTLSTASEGPLADKGLAESSLALLMDNSGEQ----DTASEDKWSSRQLSDLRAADNLDQPFPEVLGEEPLAEDE---GPLWAAVPVQTGPQYADCAVLPMGAMAAEQWEEDPAMVAWSIAPEPMPQEETSMWPFEGLEQLQ--PPPMEIPYHEILWREWEDFSTQPDAQGLEAGDGPQFQFTLMSYNILAQDLMQQSSELYLHCHPDILNWNYRFANLMQEFQHWDPDILCLQEVQEDHYWEQLEPSLRMMG--FTCFYKRRTGCKTDGCAVCYKPTRFRLLCASPVEYF-----RPGLELLNRDNVGLVLLLQP----LVPEGLGQVSVAPLCVANTHVLYNPRRGDVKLAQMAILLAEVDKVAR-------LSDGS--HCPIILCGDLNSVPDSPLYNFIRDGELQYNGMPAWKVSGQEDFSHQLYQRKLQAPLWPSSLGITDCCQYVTSCHPKRSE-RLKYGRDFLLRFRFCDLACQRPVGLVLMEGVTDTKPDRPAGWAECIFEEEISELEPVFPRTIG-TIQHCLHLTSVYTHFLPQHGRPEVTTMPLGLGMTVDYIFFSAE----SCENENRSDHRLDRDGTLKLLGRLSLLSEEILWAANGLPNPFYSSDHLCLLASFGMEVTAP------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCU0-1", "uniprot_id": "ANGE1_MOUSE", "id": "Q8VCU0-1", "name": "RNA 2',3'-cyclic phosphatase ANGEL1", "aln": "MIASCLYYLLLPAARLFRFLSDAFFT--------------------CRKNALLAKS--SSPQVEGNFAMAPRGPDQEECEGLLQQWREEGWNQTPSTASEGPLADKGLAESSLALLMDNSGEQ----DAASEDKWSSRQLSDLRAAENLNQPFPEVLGEEPLAEVE---GPLWAAVPVQTGPQYADCAVLPMGAMAAEQWEEDPAMVAWSIAPEPMPQEETSMWPFEGLEQLQ--PPPMEIPYHEILWREWEDFSTQPDAQGLEAGDGPQFQFTLMSYNILAQDLMQQSSELYLHCHPDILNWNYRFANLMQEFQHWDPDILCLQEVQEDHYWEQLEPSLRMMG--FTCFYKRRTGCKTDGCAVCYKPTRFRLLCASPVEYF-----RPGLELLNRDNVGLVLLLQP----LVPEGLGQVSVAPLCVANTHVLYNPRRGDVKLAQMAILLAEVDKVAR-------LSDGS--HCPIILCGDLNSVPDSPLYNFIRDGELQYNGMPAWKVSGQEDFSHQLYQRKLQAPLWPSSLGITDCCQYVTSCHPKRSE-RLKYGRDFLLRFRFCDLACQRPVGLVLMEGVTDTKPDRPAGWAECIFEEEISELEPVFPRTIG-TIQHCLHLTSVYTHFLPQHGCPEVTTMPLGLGMTVDYIFFSAE----SCENENRTDHRLDRDGTLKLLGRLSLLSEEILWAANGLPNPFYSSDHLCLLASFGMEVTAP------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UNK9-1", "uniprot_id": "ANGE1_HUMAN", "id": "Q9UNK9-1", "name": "RNA 2',3'-cyclic phosphatase ANGEL1", "aln": "MIASCLCYLLLPATRLFRALSDAFFT--------------------CRKNVLLANS--SSPQVEGDFAMAPRGPEQEECEGLLQQWREEGLSQVLSTASEGPLIDKGLAQSSLALLMDNPGEE----NAASEDRWSSRQLSDLRAAENLDEPFPEMLGEEPLLEVEGVEGSMWAAIPMQSEPQYADCAALPVGALATEQWEEDPAVLAWSIAPEPVPQEEASIWPFEGLGQLQ--PPAVEIPYHEILWREWEDFSTQPDAQGLKAGDGPQFQFTLMSYNILAQDLMQQSSELYLHCHPDILNWNYRFVNLMQEFQHWDPDILCLQEVQEDHYWEQLEPSLRMMG--FTCFYKRRTGCKTDGCAVCYKPTRFRLLCASPVEYF-----RPGLELLNRDNVGLVLLLQP----LVPEGLGQVSVAPLCVANTHILYNPRRGDVKLAQMAILLAEVDKVAR-------LSDGS--HCPIILCGDLNSVPDSPLYNFIRDGELQYHGMPAWKVSGQEDFSHQLYQRKLQAPLWPSSLGITDCCQYVTSCHPKRSE-RRKYGRDFLLRFRFCSIACQRPVGLVLMEGVTDTKPERPAGWAESVLEEDASELEPAFSRTVG-TIQHCLHLTSVYTHFLPQRGRPEVTTMPLGLGMTVDYIFFSAE----SCENGNRTDHRLYRDGTLKLLGRLSLLSEEILWAANGLPNPFCSSDHLCLLASFGMEVTAP------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q6S3-1", "uniprot_id": "A0A8M9Q6S3_DANRE", "id": "A0A8M9Q6S3-1", "name": "RNA 2',3'-cyclic phosphatase ANGEL1", "aln": "MIVSAMFYALYPLSRLLDRVSAAWQKPPPVHVNGREVWDGGGQQQQQTEDSLQRNSTERSAQLPQDKHTHTHHPQGTLVETLERARAEEELQKTLCDVSQ---MEGVLSETPLAGLEDTHNPQPVKNQAESDYVFSSVAGKHSEISPHLTADAPSEADRCDGVSAS----SGGAALLFASRSPVFDLSALLS---DTQQLQMDAEPIGWHFPVG-HGLAEMCYCPYVQFPDVSYYPAFQDQDNIEVMWRVWEDLSEPQSSDSADAS--PVFDFSVMSYNILAQDLLEANPHLYTHCAEDALRWENRLQAVLKELQIWQPDIVCLQEVQEDHFQEQMHPVLINMG--YTCIYKRRTGSKTDGCAVLYRGERFTQLSVSLLEFR-----RSECELLDRDNVGIVLLLQP----TAGP---HHQFTPVCVANTHLLFNPRRGDVKLAQLAIMFAEIHSVMQKC-----RSEGK--SCELILCGDFNAVPRSPLWTLITTGELYYHGLPTWMVSGQTDLSYKAHHNRLFSPLWPSSLGITDRCQYNTDTHTTASDGKQQYSHEFMCQLRFCEAACVRPADLELIPGVTDKTPD----------------LRDMFSLRFSPSLRHRLSLTSAYSHIHPETLTDLVTTLNSEGAAMVDYIFYSQR----QKSGFNGGGE---SAGGLKLLARLSLLSEAHLWSLRGLPNESFPSDHLSLLVKLQLSSADI------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q03210-1", "uniprot_id": "NGL3_YEAST", "id": "Q03210-1", "name": "Probable RNA exonuclease NGL3", "aln": "---------------------------------------------------------------------MDS-----QVEGKISPSQ-----------KESSSTSGLVSPSEDGPAHQKIHRD----------QLSVDQIKKIREERAQKRQVRRNSLISQGKDPD---------------------------------------------------------------------FPTPDLQFIERPFLPINHDNSKGLTPATIQVTQDSLDVKIMTYNTLAQTLIRRD---FFPESGPALKWHKRSKVLVHELKKYRPDVVSLQEVDYNELN-FWQENFHKLG--FDVIFKR-HEGKTHGLLVAWNNKKFQLDNDWMLDYDNILAGNVISARTRTKNIALIISLYFKGITDS-----SSR--GIIVANTHLFWHPFGVFERLRQSYLVLQKIQEIKACS-----KYNG----WHSLLMGDFNTEPEEPPYLAITKRPLILKGPIRAMVECSLAYRYSKKRNGEESDQDDEECDEKSRGEGHSDQPQNPKP-ESFTATKEEKALVNQLVALHNSLHVKGVS---------------------------LYGIGYG-------KVHPENA--NGSHGEPGLSNWANTWCGLLDYIFYIEG-DHNQDTRQKEPLNAFEGNNNVKIIGYLRMPCAQEMPKHSQPFEGEYASDHISLMCQIRLFFGGEKVHSLK", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q03264-1", "uniprot_id": "NGL2_YEAST", "id": "Q03264-1", "name": "RNA exonuclease NGL2", "aln": "---------------------------------------------------------------------MTQDKEVKVVAPDVAPDQEVEINKSVKDAKHQTNDDSLLQHKKKG-KKGKKSKP----------IVTPEHIAKVRAEREVMRKAKRDAMLAQGVDPD---------------------------------------------------------------------CP-PELHFIRRPFLSLHEAEP---------VTG--FRFKLMTYNCLAQALIRRK---LFPDSGDALKWYRRSKVLLNEFKYYNSDVICLQEIDHIQFQSFWKDEFSKLG--YDGQYYR-NATKNHGVAIMWRRELFHQVDKMLIDYDKESS-ESISTRTTTNNVGLVLALKFSEKVLSNLGKKSSKKCGILIGTTHLFWHPFGTYERTRQCYIVLKKMKEFMHRVNVLQNENDGDLSHWFPFFCGDFNSQPFDTPYLSMTSKPVHYRNRAKTVIGCSTSYKFSKVRDGEEGADDEEGGNIEKYGK---DQPESPVP-EKFHANEEQSELVDKMAQLHNSLDMRAIS---------------------------LYSVGYK-------NVHPENAGLDNDRGEPEISNWANTWRGLLDYLFYVKKWDPQSNCQEVETLGDFEKENKVKCRGFLRMPPGNEMTKHGQPHVGEYASDHLSMVCDLELQL---------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q24239-1", "uniprot_id": "ANGEL_DROME", "id": "Q24239-1", "name": "Protein angel", "aln": "------------------------------------------------------------------------------------------MYRSLLHNVSLKATSRIIRRSVSSQAKGASGKR-------------KQKAKEMESSHDRNRRWTSLGNQAEGRDPH------------------------------------------------------------------------------------------------------KCSSFKVVSYNILAQDLLLEHLFLYVGIPHEFLSWQRRQQNLLRELLKLDPDILCLQEMQFDHLPVLVQRLRMGNGKKLAYVYKKKTGCRTDGCAIVYDSSKFELLDHQAVELY-----DQAVALLNRDNVALFARFRFK--------KQQEQQKEFVVATTHLLFNTKRSDVRCAQVERILEELQSFSTDT--------------PIVLTGDFNSLPDSSPIEFLVGKNGDVD-----------------------------------------------------------------STACPEPLHFEIID-----------------------------------------------------SGEGTASTYQN-EWVIVDYILRSLG---------------SRSRHKLLPLSVYSLPSINRCIGAGQIPNYRLGSDHYALGAVFTVV----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . . . . . ..:::** *** *: * * * ::.*: .*::.***:: . . * : : :..* : : * :: .*:.:. : . :..**::::. : * :: ::... .: **:*: * .. : .. . : :. :**:: : . : *** .: : : ", "identical_positions": 30, "similar_positions": 80, "identity": "4.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111020-14", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UPI3-1", "uniprot_id": "FLVC2_HUMAN", "id": "Q9UPI3-1", "name": "Choline/ethanolamine transporter FLVCR2", "aln": "MVNEGPNQEESDDTPVPESALQAD------------------------PSVSVHPSVSVHPSVSINPSVSVHPSSSAHPSALAQPSGLAHPSSSGPEDLSVIKVSRRRWAVVLVFSCYSMCNSFQWIQYGSINNIFMHFYGVSAFAIDWLSMCYMLTYIPLLLPVAWLLEKFGLRTIALTGSALNCLGAWVKLGSLKPHLFPVTVVGQLICSVAQVFILGMPSRIASVWFGANEVSTACSVAVFGNQLGIAIGFLVPPVLVPNIEDRDELAYHISIMFYIIGGVATLLLILVIIVFKEKPKYPPSRAQSLSYALTSPDASYLGSIARLFKNLNFVLLVITYGLNAGAFYALSTLLNRMVIWHYPGEEVNAGRIGLTIVIAGMLGAVISGIWLDRSKTYKETTLVVYIMTLVGMVVYTFTLNLGHLWVVFITAGTMGFFMTGYLPLGFEFAVELTYPESEGISSGLLNISAQVFGIIFTISQGQIIDNYGTKPGNIFLCVFLTLGAALTAFIKADLRRQKANKETLENKLQEEEEE---SNTSKVPTAVSEDHL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91X85-1", "uniprot_id": "FLVC2_MOUSE", "id": "Q91X85-1", "name": "Choline/ethanolamine transporter FLVCR2", "aln": "MVNESLNQEESNDRPAPESEFQMDTSYSTQPSGSIHPSVSGHPSVSGHPSVSGHPSVSIHPSVSIDPSVSVRPSSSALPSTLAQPSGLTHHSSLVRED-SVIKVSKRRWVVVLVFSCYSLCNAFQWIQYGSINNIFMNFYGVSAFAIDWLSMCYMLTYIPLLLPVAWMLEKFGLRTIAITGSALNCLGAWVKLGSLEPHLFPVTMVGQVICSVAQVFILGMPSRIASVWFGADEVSTACSVAVFGNQLGIAIGFLVPPVLVPNIKDPEKLAYHISIMFYIIGGVATFLFILVIIVFKEKPKHPPSRAQSLSYALATTDASYLSSIVRLFKNLNFVLLVITYGLNAGAFYALSTLLNRMVILHFPGEEVNAGRIGLTIVIAGMFGAMISGIWLDKSKTYKETTLVVYIMTLVGMVVYTFTLNLNHLWVVFITAGTLGFFMTGYLPLGFEFAVELTYPESEGVSSGLLNVSAQVFGIVFTISQGQIIDNHGTMFGNIFLCVFLALGSALTAFIKSDLRRQRANKDAPETKVQEEEEEEEGSNTSKVP-VVSEAHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4ILB2-1", "uniprot_id": "FLC2A_DANRE", "id": "A0A0R4ILB2-1", "name": "Choline/ethanolamine transporter flvcr2a", "aln": "MCDKADN------------------------------------------------------------HIDVQPEGNLEVSSVSS-----------------TRLYRRRWVILLLFSSYSLCNAFQWIQYGIINNIFMKFYQVSSFAVDWLSMVYMLTYIPFIFPVTWLLERKGLRVVALLAASINCAGTWIKVASVQPSLFWVTMLGQFACSCAQVFILGMPSQVASVWFGSDEVSTACAIGVFGNQLGIAIGFLVPPVLVPNVEDMGELAEHISIMFYITAAVATLIFLLVVFVFQEKPETPPSLAQVALRNMPTGQHSYLASIARLMCNKPFILLLISYGLNVGSFYAVSTLLNRMIIEHYPGEEVNAGRIGLTLVVAGVVGSLICGVWLDKTKTYKQTTLSVYLLSFVGMLIYSFTLNLGHLWLVFLTSGVLGFFMTGYLPLGFEFAVELTYPESEGTSSGLLNCSAQVFGIAFTIIQGKIIDHFGTLAGNIFLCVFLLIGSIMTAFIKSDLRRQKANQETGGNADSSVHPQ----HGETLP--VKEVKM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ::. * :.*:*... *:::. :: :***.::*:**.**:**:******* ******:** **:**:***** *******:::**:*:**: ***.:*: .:::** *:*:*:.*::* ** **::**. ** **********::******::******::.*********************::* :** ******** ..***::::**::**:***: *** ** :.: : ***.**.**: * *:**:*:****.*:***:*******:* *:*************:*:**:.*::*.*:***::****:*** **::::***::*:*****.***:**:*:*.:************************* ****** ******* *** **:***:.** ********* :*: :*****:*****:**::: . .. . : : ..:* *.* ::", "identical_positions": 288, "similar_positions": 130, "identity": "52.08%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111027-16", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43025-1", "uniprot_id": "TETN_MOUSE", "id": "P43025-1", "name": "Tetranectin", "aln": "MGFW-GTYLLFCLFSFLSQLTAESPTPKAKKAANAKKDLVS--SKMFEELKNRMDVLAQEVALLKEKQALQTVCLKGTKVNLKCLLAFTQPKTFHEASEDCISQGGTLGTPQSELENEALFEYARHSVGNDANIWLGLNDMAAEGAWVDMTGGLLAYKNWETEITTQPDGGKAENCAALSGAANGKWFDKRCRDQLPYICQFAIV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P05452-1", "uniprot_id": "TETN_HUMAN", "id": "P05452-1", "name": "Tetranectin", "aln": "MELW-GAYLLLCLFSLLTQVTTEPPTQKPKKIVNAKKDVVN--TKMFEELKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGIV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F0Y1-1", "uniprot_id": "E7F0Y1_DANRE", "id": "E7F0Y1-1", "name": "", "aln": "MTLRDGRFLLPLLLLTLFTHSSLQQQNTSKKKTPDKKDSESRVSAALEDLQQQISDIVEELNLLKEQQALQTVCLKGTKIHGKCFLADSMKKRYHTANEDCIAKGGILATPLSSAQNTQLYEYMRQSISADAEIWLGVNDMQTEGLWTDQTGSAIRYKNWK---LPQPDGGSAQNCAVLT--SGGKWLDESCREERASICEFNIV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : * :** *: * :: ..** . *** . : :*:*:.::. :.:*: ****:************:: **:** : * :* *.****::** *.** : :* *:** *:*:. :*:****:*** :** *.* **. : ****: .*****.::***.*: :.***:*: **:: . **:* **", "identical_positions": 90, "similar_positions": 59, "identity": "43.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111027-17", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U462-1", "uniprot_id": "CDCP1_MOUSE", "id": "Q5U462-1", "name": "CUB domain-containing protein 1", "aln": "MAHSACGFSVALLGALLLGTARLLRGTEASEIALPQRSGVTVSIKLGNPALPVKICYIVMSRQHITELIIRPGERKSFTFSCSNPEKHFVLKIEKNIDCMSGPCPFGEVHLQPSTSELPILNRTFIWDVRAHKSIGLELQFATPRLRQIGPGESCADGVTHSISGHIDATEVRIGTFCSNGTVSRIKMQEGVKMALHLPWFHRRNVSGFSIANRSSIKRLCIIESVFE-GEGSATLMSANYPGGFPEDELMTWQFVVPAHLRASVSFLNFNVSNCERKEERVEYYIPGSTTNPEVFRLEDKQPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQRPQDESNKTYMVDLSRERTMSLTIEPRPVKHGRRFVPGCFVCLESRTCSTNVTLTAGSIHKISFLCDDLTRLWVNVEKTLSCLDHRYCYRQSFKLQVPDYILQLPVQLHDFSWKLLVPKDKLSLMLVPGQKLQQHTQERPCNTSFGYHVTSTTPGQDLYFGSFCS--GGSIEKIQVKQNSSVTLRAYAPSFQQEVSKQGLIVSYTPYFKEEGIFTVTPDTKNKVYLRSPNWDRGLPALSSVSWNISVPSNQVACLTVLKERSGLACQSGRAFMIIQEQQSRAEEIFSLEEEVLPKPSFHHHSFWVNISNCSPMNGKQLDLLFWVTLTPRTVDLAVV-IGAAGGGALLLFALVLIICFVKKKKK-VDKGPAVGIYNGNVNTQMP-QTQKFPKGRKDNDSHVYAVIEDTMVYGHLLQ------DSGGSFIQPEVDTYRPFQGPMGDCPPTPPP-------------LFSRTPTAKFTAEELAPSSPPES------------ESEPYTFSHPNKGEIGVRETDIPLLHTQGPVETEE----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H5V8-1", "uniprot_id": "CDCP1_HUMAN", "id": "Q9H5V8-1", "name": "CUB domain-containing protein 1", "aln": "MAGLNCGVSIALLGVLLLGAARLPRGAEAFEIALPRESNITVLIKLGTPTLLAKPCYIVISKRHITMLSIKSGERIVFTFSCQSPENHFVIEIQKNIDCMSGPCPFGEVQLQPSTSLLPTLNRTFIWDVKAHKSIGLELQFSIPRLRQIGPGESCPDGVTHSISGRIDATVVRIGTFCSNGTVSRIKMQEGVKMALHLPWFHPRNVSGFSIANRSSIKRLCIIESVFE-GEGSATLMSANYPEGFPEDELMTWQFVVPAHLRASVSFLNFNLSNCERKEERVEYYIPGSTTNPEVFKLEDKQPGNMAGNFNLSLQGCDQDAQSPGILRLQFQVLVQHPQNESNKIYVVDLSNERAMSLTIEPRPVKQSRKFVPGCFVCLESRTCSSNLTLTSGSKHKISFLCDDLTRLWMNVEKTISCTDHRYCQRKSYSLQVPSDILHLPVELHDFSWKLLVPKDRLSLVLVPAQKLQQHTHEKPCNTSFSYLVASAIPSQDLYFGSFCP--GGSIKQIQVKQNISVTLRTFAPSFQQEASRQGLTVSFIPYFKEEGVFTVTPDTKSKVYLRTPNWDRGLPSLTSVSWNISVPRDQVACLTFFKERSGVVCQTGRAFMIIQEQRTRAEEIFSLDEDVLPKPSFHHHSFWVNISNCSPTSGKQLDLLFSVTLTPRTVDLTVILIAAVGGGVLLLSALGLIICCVKKKKKKTNKGPAVGIYNDNINTEMPRQPKKFQKGRKDNDSHVYAVIEDTMVYGHLLQ------DSSGSFLQPEVDTYRPFQGTMGVCPPSPPT-------------ICSRAPTAKLATEEPPPRSPPES------------ESEPYTFSHPNNGDVSSKDTDIPLLNTQEPMEPAE----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8PY98-1", "uniprot_id": "A0A2R8PY98_DANRE", "id": "A0A2R8PY98-1", "name": "", "aln": "---MGSSAVPVLIGLILLHIHKIS-ECQTIEVTPDPSTNVIFSKKPGQGLDCTVCKNEDSSQSCDSSLRLTESKTTSVSFNCSQPGDVFTVEINQDIDCSSSACSS--IAVHPDATRFLEFSRSFTWDVKVHSSKMFHLDFPAPGMRQIKPSESCPDQHTYSITSYQRTGPISIGSFCRNGTISRIQVWYRGRISLEVPKGTPLNPSDFRVSIGPASTGLVEVDVKLPRAESSVDFFTPNYGTGYYNAYKVKWNFAVEPIVNFTVEFKAYAPPECQKKEVTVDYALGEKTS--FTTKPTDIQPNNKQGDFSLTLNNCDAKS-TPKVPGLSMHIMVGVFRGGIPYLCTVDLQNEEGLSLEIVNTNPQSYCEMRS-------NSVVQEKIVVPVGSKVDLYFLDCPAQDLRLTATKTIDFSGVSARSVSRTPLIIPPMKWSLPVALNEFSWLLRVPDQTTLDLTSAQRNLHQSVPDKPCKEKVSLLVSESLGSS---IGQFCSPADGAIQKIQIRGNVSITVSPNTVKDLSQETDPFLNITLSPEITENVIYTVSPLISGPAYLASPYWPDAMQPSSSASWIINVPPEYRANLWFTN-VSKPTCDSGHAELEISPLDSSAETQEWREDQSFPDSIVQQTSFYLNMSNCEPASG-RYALLTKIIVQKESKKILAIILAVVGAVLALLIVALVVVCVIRKKHK--PSGNRSSIYIPKGKPVLP-GNATFPKSRTDNESHVYASIDETIYNRHLDTNHPADSNNGTWTNGHQVDTYRPFLGPTDSIPTDQDLPDGYSLDRGRDKDVFQPFLTPPNTFNLPRPRSPLISQGSLGFEDRRMVDNELNTFKAAGDINPIRLSTDECKLRPQMDSDSDSYHEPEYEEAM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. .*:* :** :: :: *:: :.: . * * . *: : * : .: .:*.*..* . *.::*:::*** *..*. : ::*.:: : :.*:* ***:.*.* :.*:*. * :*** *.***.* *:**:. : : **:** ***:***:: :::*.:* * *.* :: .: . * :: : .*.*. :::.** *: : :.*:*.* . :. :*.* : .:*::** *:* : .*: . : * **.* *:*.*:*:.** .: :* : *.::::* :. ***..*. :** * : .: . . . . ::.:. ** .: ** * :.. **:. . . * :* *** *::*** * **.: : . ::*:* . ::**: ... *:.: .. :*.**. .*:*::**:: * *:*: . : . .: : * :: * :.*: ::**:* .. .** :* * .: . :*.** *.** : * * . : * .*::*:* : *. : ** ::: :*.. .:: **::*:***.* .* : ** : : .: .: .: :...*. ** . :::* ::**:* .* .** : :. :* .* *.*.**:***** *::*: ** :.. :******* *. . *. : . *. : : * ** * :.* **. ... : .** *..* :. . ", "identical_positions": 209, "similar_positions": 290, "identity": "23.75%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111027-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60266-1", "uniprot_id": "ADCY3_HUMAN", "id": "O60266-1", "name": "Adenylate cyclase type 3", "aln": "MPRNQGFSEPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPESLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDKLASLAVAGIGLVLDIILFVLCKKGLLPDRVTRRVLPYVLWLLITAQIFSYLGLNFARAHAASDTVGWQVFFVFSFFITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQEELKGMQLLREILANVFLYLCAIAVGIMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDESQKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGDGGSRCDYLEEKGIETYLIIASKPEVKKTATQNGLNGSALPNGAPASSKSSSPALIETKEPNGSAHSSGSTSEKPEEQDAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESAQVVKKRNTFLLSMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLLCTALVEILIDPWLMTNYVTFMVGEILLLILTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMANVVDMLSCLQYYTGPSNATAG---METEGSCLENPKYYNYVAVLSLIATIMLVQVSHMVKLTLMLLVAGAVATINLYAWRPVFDEYDHKRFREHDLPMVALEQMQGFN-PGLNGTD-RLPLVPSKYSMTVMVFLMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEHVARHFLGSKKRDEELYSQTYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFASSNKEDKSERERWQHLADLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDKLATFPNGPSVTLPHQVVDNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VHH7-1", "uniprot_id": "ADCY3_MOUSE", "id": "Q8VHH7-1", "name": "Adenylate cyclase type 3", "aln": "MPRNQGFSDPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPESLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCAVVFSSDKLAPLMVAGFGLVLDIILFVLCKKGLLPDRVSRKVVPYLLWLLISAQIFSYLGLNFSRAHAASDTVGWQAFFVFSFFITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDELEGMQLLREILANVFLYLCAIIVGIMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDESQKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQLRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTMDCLKGEFDVEPGDGGSRCDYLDEKGIETYLIIASKPEVKKTA-QNGLNGSAVPNGAPASSKPSSPALIETKEPNGSAHASGSTSEEAEEQEAQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESAQVVKKRNTFLLTMRFMDPEMETRYSVEKEKQSGAAFSCSCVVLFCTAMVEILIDPWLMTNYVTFVVGEVLLLILTICSMAAIFPRSFPKKLVAFSSWIDRTRWARNTWAMLAIFILVMANVVDMLSCLQYYMGPYNMTAG---MELDGGCMENPKYYNYVAVLSLIATIMLVQVSHMVKLTLMLLVTGAVTALNLYAWCPVFDEYDHKRFQEKDSPMVALEKMQVLATPGLNGTDSRLPLVPSKYSMTVMMFVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEHVARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDFDSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFTSSSKEEKSDKERWQHLADLADFALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGVMGNIQVVEETQVILREYGFRFVRRGPIFVKGKGELLTFFLKGRDRPAAFPNGSSVTLPHQVVDNP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B5T8-1", "uniprot_id": "A0ACD6B5T8_DANRE", "id": "A0ACD6B5T8-1", "name": "adenylate cyclase", "aln": "MPRNRAFSEPEYSAEYSADCSVTLPSDPGQAVGRTHEVTVRSSGCCLCLPRFMRLTFAPDSLENLYQTYFRRQRHETLLVLVVFAALFDCYIIVMCTVLYTADKLASVAVASVGLAADVLLYLLCRYGLLPDRVTRRLVPYALWVLIAAQIFCYLGLNFARFHQPSDTVGWQAFFSFSFFLTLPLRLTPIVLITSVSCGVHTLVLGVTIAQQQQEDIQGAALGRQLLANMVIYVCAITVGVMSYYMADRKHRKAFLEARQSLEVKLNLEEQSQQQERLLLSILPKHIADEMLQDMKKEASQKEMQQFNTMYMYRHENVSILFADIVGFTQLSSSCSAQELVKLLNELFARFDKLAAKYHQLRIKILGDCYYCICGLPDYREDHAACSIMMGLAMVEAISYVREKTQTDVDMRVGVHSGMVLGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQNTLECLHGEFDVEPGNGGDRCEYLKERGIETYLVVLPK----GPVGKNGINGVKLS---VTSSNGNSPLLINTTECNGSVHTACTTPEDPEELDTRVVNPSFPNPRRRLRLRDLAERVIDAQENEQELNKLLNEALLERETVQALKGKYTNRLSLRFTDPELETRFSVEKEKQSGAAFSCSCVVLLFTAVMEALIDPWLVANYVTLAVGEVLLLILTICSLAAIFPRVFPKRLVSFSTWIDHTRWARNTWAMAAIFIVTLADIVDMLSCRAPQTSTVESTAVPPVVTAIRGCAENPKYYSFIAVLALIATTMLVQVSHMVKLTLMLLITVATGAVNIYSWSQTFDLYDLTRFKEY-----------------------RVNLVPSKYTMSVMIFIMMVSFYYFSRHVEKLARTLFLWKIEVHEQKEKVYEMRRWNEALVTNMLPEHVARHFLGSKKRDEELYSQSYDEIGVMFASIPNFSDFYTEESINNGGIECLRFLNEIISDFDSLLDEPQFRCITKIKTIGSTYMAASGVTSDNNTNGYACMKKEEISDRERWQHLADLADFALAMKVTLMNINYQSFNNFMLRIGLNKGAVLAGVIGARKPHFDIWGNTVNVASRMESTGVMGNIQVVEDCYCILKDYGFRFVRRGPIFVKGKGELLTYFLKGREKQGSFINGSFVTLPHQVVDSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:.**:*********: **:*****.:.******::**.**.************.*:**********:********************::***:*::::****.: **..**. *::*::**: *******:*:::** **:**:****.******:* * .*******.** ****:**** *:***:*: *** *********:*****::::* * *::***:.:*:*** **:************************:**********.*:*******:*****:****: ***: *****************************:**************************************************.***:****************:*.********:* ***************************************.*::**:********:**.**:**.*:******:: .* .. :**:** :. :**: .** **:*.* ***.*:: :*.*..** :::. *************:***:**:**.*:*:***:**********:.*.:* : * *::** ***:***:*******************: **::* ******::****: ***:*********:****** ***:**:**:***:********** ****:.:*::****** .. : ** : .* ******.::***:**** ****************:: *. ::*:*:* .** ** .**:* *: ******:*:**:*:**:************************:***:*************************************:**********:***:*******************************:*:** ******************.* ****::. .**: *::***************** ** *** ***********:***.************:**************************: **::*********************:*****:: .:* **. *********..", "identical_positions": 849, "similar_positions": 192, "identity": "73.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111028-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RC54-1", "uniprot_id": "M0RC54_RAT", "id": "M0RC54-1", "name": "", "aln": "MATNPQPQPPPPAPPPPPPQPQP--PPPPPGPGAGPGASGPGGAGAGSGDPQLVAMIVNHLKSQGLFDQFRR-DCLADVDTKPAYQNLRQRVDNFVANHLATHTWSPHLNKNQLRNNIRQQVLKSGMLESGIDRIISQVVDPKINHTFRPQVEKAVHEFLATLNHKEETAGSTAPDDEKLESSVITQGAPAPGPSANVASDAMSILETITSLNQEANAAARASTEMSNAKASERISRKLSSQPSTDISTDKERGSEDGAEREKVTPDSGGEGLETAPKSEEPNDLPCPVEETKNHTKEN-SLLFLSKDAQQENSDPKIKSTDKGEKKPDGNEKGERKKEKKEKTEKKIDHSKRNEDTQKVKDERQAKDREAESTKLPSEKISSRARAAEGTKEDCSLVDSD-VDGLTDITVSSVHTSDLSSFEEDTEEEVVMSESMEEGEITSEDEEKNKQNKTKAQTSDSTDGKARSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRRINREKLEEKRKQKAEKTKSSKAKSQGKSSVDLEDSSTKTLEPKAPRIKEVLKERKVLEKKVALSKRRRKDSRNADESSKKKPQAEEESKEALKTSEHCEKEKASS-KDLKHTHGKGEPNRPARRLSESLHSVDDNKTESKVEREYKRRTSTPVVLEGAQEETDSRDGKKQPDRSEINMEETQKQKSTLKNEKYQKKDDPET-HGKGLPKKEAKSAKERPEKEKAQSEEKSSSKHKHKSDSVHKVGDETEPHSSEKS-EAEESVRKQSQQTKLSSDDKTERKRKHRNERKLSVLGRDGKPVSEYTIKTDEHARKDN-KKDKHLSSEKTKAEHKSRRSSDSKLQKDVLSSKQHSVTLQKRSESCSEDKYETDSTNADSSSKPEELLHKERRRTKSLLEEKLVLKSKSKSQGKQIKVAETESQEGVTKQVTTPKPDKEKNTEDNDTERQRKSKLEDRTCEEAVAEPALESAVPSAHSSQKDSGHRAKVASVKEKHKTDKDSTSSKLERRVSDGHRSRSLKHSNKDVKRKEENKPDDKNGKEVDSSHEKGRGNGPVTEKKLSRRLCENRRGSTSQEMAK-EDKLAANLSGTASTSSLQRPKKSTETALIPEQEPMEIDSEAAVENVSELSKTEDISSNSSQQDTDFENVTKHKAAAGVLKDELRTSMVDSKPAAAVTCKSGRGLTITSNSEKHADHKSTLTKKVHSQSTASKATPREREPAQRGAQEISVDSEGSRKVLSRALSENEKGQKNLKGVSKTTEECGTHRNASLEFSTDSDLLSSLGSVSVVPQKESHDSSTITVVDREAISEGGKASTSLVNHSDIPNQNLAVKKSEILKTNGSKEGNDGFTVDILAKANGSGKRHLSEDSQAMLLCSKEGKVGIALAGKPSGVIGENKSISKQRSLMGTAKKESDLNVDPDVKQ-----------DSAAGEHVVDLTTRKEAETIRRKHNKDPDESKKIPTDIERKTENSEVDTSARRDSAP-VPQQRHGKMERGAAGSGRRDKSFIATSTEGTDKGIMLNTIKAGDATTTSSETGGKGVALPCTSIEADEGFIMGACPRNNPLQVGAEASECTVFAAAEEGKGVVTEGFAESEILLTSSKEGESGECTVAESEDRVAGPLTAHTVQAETNVNSITTEEKDDAVTSAGSEEKCGGSSCA----VEGTATFVGEVESDGAVTSAGTEIRAGSVSSEDVDGSQENRIQVGPKKETEGTVTCTGAKGRNDNFVFCLVTGAGTQEQRVVTGADVVQENDDKSLEASANQ-GDGSGTDGTEGESAVTSTGITEEDGEASANCTGSEDSTEGCAISSETEENAESAMDSTEAKDMTNTPLVATGPCDDEGIVTSTGAKEEDEEDEGVVTSTGRGNETGHASACTGIEE-SEGMLVCESGEGGGPIGPTMDHVDAEAGAAAMNTNDSNVDSMSGAEKEIKDTDICSSAKGIVESSVTSAFAGNSDRPPVLESSENPMASATSHHSDSQLTRKETVEDTTISTGLVRGSDDVLLSGAVPEYEVGHMSPRE-----------NEECDGLMASTASCDVSNKDSLAGSKSQGNGLVIPTS-TNDCTPPISAVIDVRGGHSCTLSTEENRNDARVHMEGFEAPMPSAISDEKSQLTASRSEEKDECAMISTSIGEEFEVPISSAVTITCAERQQPVAA-VEESTTGPALVSTEDFEIPMPSAPTEAESPLASTSKEEKDECALISTSIAEECEASASGVSRNAP----------SDGNAVISTSSVEDCEGSVSSAVPQESVCPSVVPVEETGDTAMISTSTSEGREAVMVGTIPTDEDQASTVRGEDLSDAAIISTSTAECVLTCTSLSRHEESQQASTHNPRGNGGRLVTKQSKCELPMPSLMTESNCKCPGPFTTGKGVGPLMAVSTRGEHDRLPVCEPSAGQSQPGTALCLGEEKSHGMDCPGQD--------------LNAKERNTLLSCVQRESKSVEAEAAGDSSTASGIVRKDSERNANSLSETNCLRRPEQKSAEDSSGSIHCLAAVNTG-AKTDNMLPITDAASECPS---DQQEPENNLKA-TTKCITGQESKMPSSHTAVLPSVCRVAPSAPKREGGLPAKSDHSGTWTSEGSAEKMGHVAGARQSYHREGNLDVTIPPEDNGCGIGNEELPPKGIEGSELSANLTTEISVSSEEDTNHGVVAAPENPCVGRPSGAAELQVEALLMSESLNVENSESRINEEIHYDSRNKEEISCGRKDSTEALSGCSAEADPEEVEEEERHISKRNRKQDYSSEEEELDDSPDVLDSRIQTAQRQCSETEPHDTKEENSGDLEEFSTLNSKANSSPA--LEDRDEFSSSEGTGEKIEPNEDDGSVKSQEDDQPIIIKRKRGRPRKYPAETAFKSKEDSKTETDITTVEQSPPGDKLKVSQADEFNKETTDLQEKSTSNDDNEEKTGS-VRRRGRKPKRSLTSSDDAESSEPERKRQKPFSETSEDKNDQDSDEEEEEEDEDEPLGATTRSATRSEAQRKNHSKPSTRATSKLGIPETVSPRNRQKLAKEKLSTSEKVSKSPPLGRSKAQLSPSVKRKRELSPPGARTRGQQKVDETPLKKAKR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q6J5-1", "uniprot_id": "BD1L1_MOUSE", "id": "E9Q6J5-1", "name": "Biorientation of chromosomes in cell division protein 1-like 1", "aln": "MATNPQPQPPPPAPPPPPPQPQP--PPPPPGPGAGPGASGPGSAGAGAGDPQLVAMIVNHLKSQGLFDQFRR-DCLADVDTKPAYQNLRQRVDNFVANHLATHTWSPHLNKNQLRNNIRQQVLKSGMLESGIDRIISQVVDPKINHTFRPQVEKAVHEFLATLNHKEEAAGSTAPDDEKPESSVITQGAPAPGPSANVASDAMSILETITSLNQEAN-AARASTEMSNAKVSERTSRKLSSQPSTDVSTDKERGSEDATEREKATSDSGGDGLEAALKSEEPSDLPCPVEETKNHMKENNSLLLLSKDAQQESTDPKIKSMDKGEKKPDGNEKGERKKEKKEKTEKKIDHSKRNEDTQKVKDERQAKDKEVESTKLPSEKSNSRARAAEGTKEDCSLLDSD-VDGLTDITVSSVHTSDLSSFEEDTEEEVVVSESMEEGEITSEDEEKNKQNKAKVQPGDSSDGKARGVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRRINREKLEEKRKQKAEKTKSSKVKSQGKSTVDLEDSSAKTLEPKAPRIKEVLKERKVLEKKVALSKRRRKDSRNVDENSKKKPQAEEESKEALKTTEYCEKEKASS-KDLRHTHGKGEPSRPARRLSESLHSADENKTESKVEREYKRRTSTPVILEGAQEETDTRDGKKQPERSETNVEETQKQKSTLKNEKYQKKDDPET-HGKGLPKKEAKSAKERPEKEKAQSEDKPSSKHKHKGDSVHKMSDETELHSSEKG-ETEESVRKQGQQTKLSSDDRTERKSKHKSERRLSVLGRDGKPVSEYTIKTDEHARKDN-KKEKHLSSEKSKAEHKSRRSSDSKLQKDALSSKQHSVTSQKRSESCSEDKCETDSTNADSSFKPEELPHKERRRTKSLLEDKVVSKSKSKGQSKQTKAAETEAQEGVTRQVTTPKPDKEKNTEDNDTERQRKFKLEDRTSEETVTDPALENTVSSAHSAQKDSGHRAKLASIKEKHKTDKDSTSSKLERKVSDGHRSRSLKHSNKDMKKKEENKPDDKNGKEVDSSHEKGRGNGPVTEKKLSRRLCENRRGSTSQEMAK-EDKLVANMSGTTSSSSLQRPKKSTETTSIPEQEPMEIDSEAAVENVSELSKTEDISSNSSQQDTDFENVTKHKATAGVLKDEFRTSMVDSKPAAAVTCKSGRGLAVTSISERHADHKSTLTKKVHSQGNPSKAAPREREPIQRGAQEVSVDSEVSRKALSRAPSENEKGQKNLKGMSKTTEECGTHRNASLEYSTDSDLLSSSGSVTVVPQKESHNSNTIPVIDREAISEGGRASTSLANHSDVPNQYSTVKKSEVHKTNGSKEGNDGFTVDMPTKANGGSKRHLSEDSQATLLYSKESKISIPLADKSMSVTGDNKNINKQRSLMGTAKRESDLKVNPDIKQ-----------DSAAGEHVVDLSTRKEAETVRRKHN------KEIPTDVERKTENSEVDTSARRDSAP-VPQQRHGKMERGAAGSGRRDKAFIATSTEGTDKGIMLNTVKTGDATTTSSEVGEKGTALPCTSIEADEGFMMGACPKKHPLQVGAEASECTVFAAAEEGKGVVTEGFAESEILLTSSKEGESGECAVAESEDRVAGPLAAHTVQAEANVNSITTEEKDDAVTSAGSEEKCGGSACT----VEGTATFIGEVESDGAVTSAGTEIRAGSLSSEDVDGSQENRIQVGPKKETEGTVTCTETKGRNDNFI-CLVTRVETQEQRVVTGADVVQVNAAKPQEANANQ-GDGSGTDGAEGESAVTSTGITEEDGEASANCTGSEDNREGCAISSETEESAESAMDSTEAKDITNAPLVAAGPCDDEGIVTSTGAKEEDDEDEGVVTSTGRGNEPGHASACTGIEE-SEGMMVCESGEGGAQIGPTIDHVNAEAGAATVNTNDSNVDSMSGAEKEIKDTNICSSAKGIVESSVTSALAGNSDRPPVLCGSEGPMASASSHHSDSQLTRKETVEDTTISTGLVKGSDDVLVSGEVPECEVGHMSPRK-----------NEECDGLMASTASCDVSNKDSLAGSKSQGNGLMISTS-TNACTPQISAVIDVRGGHLSTLSTEEIRDGVRVHREGFEAPMPSAVSGENSQLTASRSEEKDECAMISTSIGEEFELPISSAVTVTCAERQQPVAA-VEESTTGPALVSTEDFEVPMPSAPTEAESPLASTSKEEKDECALISTSIAEECEASVFGVSRNAPSV--------TDGNAVISTSSVEDCEGSVSSAVPQESVCPSVIPVEETGDTAMISTSTSEGREAVMVGTIPTDDDQATTVRGEDLSDAAIISTSTAECVLTCTSLSRHEENQQA-THNPEGNGGHLATKQSKCELPMPSLVAERNCKCPGPFRMGKGVGPLMAVGTRGEHDRLPVCEPSVGQGQPGTALCLGEEESHGMDCPGQD--------------LNAKERNTLLSSVQRESKSAEAEAAGDSSTARRTVRKDSERNANSLSETNCLREPEQKPAEDTSGSTHCLTAVNPG-AEADGMLPITHAALEYP----DHQEPESNLKT-TTKCITGQESQMPSSHTGVLSAVCHVAPCASEQEGGLPTKSDHSGTWTSEGSPEKMGHVAGARQSFHREGNLDVTLPPEDNGCGVGNEESPPKGIGGLELSTGLTTEISVSSEEDTSHGVVAAPENPCVGRRRGAAELQMEALLMRESLNVEKSESRINEEIHFESQNKEEICCGRKGSTEALSGCSVEADPEEVEEEEKQISQRNRKPDYSSSEEELDDSPDVLDSRIETAQRQYSETEPHDTKEENSGDVEEFSSVTSKTNSSTG--LEDRDEFSSSEGTGEKTEPNEDDGSIKSQEDDHPIIIKRRRGRPRKYPAETAFKSKEDSKTETDITTVEQSSPSGKLKVSQADESNKEIANLEEKSTSNDDSEEKTAS-MRLRGRKPKRSLTSSDDAESSEPERKRQKSVSETSEDKKDEESDEEEEEEEEEEPLGATTRSATRSEAQRKNHSKPSTRATSKLGIPETISPRNRQKLAKEKLSTSEKVSKSPPLGRSKAQLSPSVKRKREVSPPGARTRGQQKVDENPLKKAKR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFC6-1", "uniprot_id": "BD1L1_HUMAN", "id": "Q8NFC6-1", "name": "Biorientation of chromosomes in cell division protein 1-like 1", "aln": "MATNPQPQPPPPAPPPPPPQPQPQPPPPPPGPGAGPGAGGAGGAGAGAGDPQLVAMIVNHLKSQGLFDQFRR-DCLADVDTKPAYQNLRQRVDNFVANHLATHTWSPHLNKNQLRNNIRQQVLKSGMLESGIDRIISQVVDPKINHTFRPQVEKAVHEFLATLNHKEEGSGNTAPDDEKPDTSLITQGVPTPGPSANVANDAMSILETITSLNQEAS-AARASTETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADKEKSTADSGGEGLETAPKSEEFSDLPCPVEEIKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTKEDFSLIDSD-VDGLTDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSEGKTKSVRHAYVHKPYLYSKYYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKSLEPKAARIKEVLKERKVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHCEKEKISSSKELKHVHAKSEPSKPARRLSESLHVVDENKNESKLEREHKRRTSTPVIMEGVQEETDTRDVKRQVERSEICTEEPQKQKSTLKNEKHLKKDDSETPHLKSLLKKEVKSSKEKPEREKTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQTKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKAEHKSRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDMDSTNMDSNLKPEEVVHKEKRRTKSLLEEKLVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKEKNTEENDSEKQRKSKVEDKPFEETGVEPVLETASSSAHSTQKDSSHRAKLPLAKEKYKSDKDSTSTRLERKLSDGHKSRSLKHSSKDIKKKDENKSDDKDGKEVDSSHEKARGNSSLMEKKLSRRLCENRRGSLSQEMAKGEEKLAANTLSTPSGSSLQRPKKSGDMTLIPEQEPMEIDSEPGVENVFEVSKTQDNRNNNSQQDIDSEN-MKQKTSATVQKDELRTCTADSK-ATAPAYKPGRGTGVNSNSEKHADHRSTLTKKMHIQSAVSKMNPGEKEPIHRGTTEVNIDSETVHRMLLSAPSENDRVQKNLK--NTAAEEHVAQGDATLEHSTNLDSSPSLSSVTVVPLRESYDPDVIPLFDKRTVLEGSTASTSPADHSALPNQSLTVRESEVLKTSDSKEGGEGFTVDTPAKASITSKRHIPEAHQATLLDGKQGKVIMPLGSKLTGVIVENENITKEGGLVDMAKKENDLNAEPNLKQTIKATVENGKKDGIAVDHVVGLNTEKYAETVKLKHKRSPGKVKDISIDVERRNENSEVDTSAGSGSAPSVLHQRNGQTEDVATGPRRAEKTSVATSTEGKDKDVTLSPVKAGPATTTSSETRQSEVALPCTSIEADEGLIIGTHSRNNPLHVGAEASECTVFAAAEEGGAVVTEGFAESETFLTSTKEGESGECAVAESEDRAADLLAVHAVKIEANVNSVVTEEKDDAVTSAGSEEKCDGSLSRDSEIVEGTITFISEVESDGAVTSAGTEIRAGSISSEEVDGSQGNMMRMGPKKETEGTVTCTGAEGRSDNFVICSVTGAGPREERMVTGAGVVLGDNDAPPGTSASQEGDGSVNDGTEGESAVTSTGITE-DGEGPASCTGSEDSSEGFAISSESEENGESAMDSTVAKEGTNVPLVAAGPCDDEGIVTSTGAKEEDEEGEDVVTSTGRGNEIGHASTCTGLGEESEGVLICESAEGDSQIGTVVEHVEAEAGAAIMNANENNVDSMSGTEKGSKDTDICSSAKGIVESSVTSAVSGKDEVTPVPGGCEGPMTSAASDQSDSQL---EKVEDTTISTGLVGGSYDVLVSGEVPECEVAHTSPSEKEDEDIITSVENEECDGLMATTASGDITNQNSLAGGKNQGKVLIISTSTTNDYTPQVSAITDVEGGLSDALRTEENMEGTRVTTEEFEAPMPSAVSGDDSQLTASRSEEKDECAMISTSIGEEFELPISSATTIKCAESLQPVAAAVEERATGPVLISTADFEGPMPSAPPEAESPLASTSKEEKDECALISTSIAEECEASVSGVVVESENERAGTVMEEKDGSGIISTSSVEDCEGPVSSAVPQEEGDPSVTPAEEMGDTAMISTSTSEGCEAVMIGAVLQDEDRLTITRVEDLSDAAIISTSTAECMPISASIDRHEENQLT-ADNPEGNGDLSATEVSKHKVPMPSLIAENNCRCPGPVRGGKEPGPVLAVSTEEGHNGPSVHKPSAGQGHP-SAVCAEKEEKHGKECPEIGPFAGRGQKESTLHLINAEEKNVLLNSLQKEDKSPETGTAGGSSTASYSAGRGLEGNANSPAHLRGPEQTSGQTAKDPSVSIRYLAAVNTGAIKADDMPPVQGTVAEHSFLPAEQQGSEDNLKTSTTKCITGQESKIAPSHTMIPPATYSVALLAPKCEQDLTIKNDYSGKWTDQASAEKTGDDNSTRKSFPEEGDIMVTVSSEENVCDIGNEESPLNVLGGLKLKANLKMEAYVPSEEEKNGEILAPPESLCGGKPSGIAELQREPLLVNESLNVENSGFRTNEEIHSESYNKGEISSGRKDNAEAISGHSVEADPKEVEEEERHMPKRKRKQHYLSSEDEPDDNPDVLDSRIETAQRQCPETEPHDTKEENSRDLEELPKTSSETNSTTSRVMEEKDEYSSSETTGEKPEQNDDD-TIKSQEEDQPIIIKRKRGRPRKYPVETTLKMKDDSKTDTGIVTVEQSPSSSKLKVMQTDESNKETANLQERSISNDDGEEKIVTSVRRRGRKPKRSLTVSDDAESSEPERKRQKSVSDPVEDKKEQESDEEEEEEEEDEPSGATTRSTTRSEAQR-----------------------------------------------SKTQLSPSIKRKREVSPPGARTRGQQRVEEAPVKKAKR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B8C2-1", "uniprot_id": "A0A8M3B8C2_DANRE", "id": "A0A8M3B8C2-1", "name": "", "aln": "------------------------------------------MAALHPGDPQLVSVIVNHLKTEGLFDQFRR-DCLADVDTKPAYLHLRQRVDNFVSNHLANHTWSPQLNKNQLRNSIRQLVQQSGMLEQGVDRIVAQVVDPKVHHTFRPQVERIVRRFLSPHSHLEEEE---------------LPAVAPPLPAEHLEAEVLIQDDAAVSWSADVQMSESAGAESN------------------------------------------------LELSVEEMDISLPEEEEELQLKEEEPLLEEEEQPQVKEEEPHVKEAELETQEAVLKEEPKEEADASKETSSKSSGKSREENPETDSQK----------------PTSVKQKTRERLREEYSLEDSD-LEGLSDITVSSVHTSDLSSFEGDSEEDEAPSESTEEGEISSEEDGGRK------TPADGSDRKPRGVRQGYVHKPFLYSRYYSDSDDEVTVEQRRRSVAKEKEERLLKRQQNRERMEEKRRLRAAQREEQERKKQASVCADAR-----------PRAKEARKEKKFLEKKVALSRQRKRDSRKEDDRKRSDTEGDSLNKEVKPAGQRSGR------------------------------VDEQRRKKSDTEEKLCDRNRVHSFILDLESGTEER--------------------------------------------QRTKTARKEVHLKDKERKDEHKLKHKLKMDSRKSTDTDEKDGGAGKG------------------GAEEKKGSKVKPDRKSSVTSKDT--------KTPEAADEANLKKGKMAADAKDKEKPKTSGKSESKLLR------------RLDSTGSSEERSEVETG--------SEVNRKKDKHPKEMLKR--------------------------SKSHPEPHPEARPGEKLKVRADRRDSSVDKTQAQKSGSEPEGD----------------------------GRKPETSLKSKTLLEKHRSKSQNPAGGKPERKTEAKSKPAEDK---------REEKKTSEEKLRDTKVRKLKVQKDSKFEE----------------------ESLDSAAVSSSTPVSDDPFAALSDVTPESEDEEVEPKEPRPLSAEADALLSLMDISVRRDVEADMKMQEAALTLLSMGPDAGRSSDVVAADDQVAMQTVATDPEDAGSLPECAAADAAAPAATVEPMETESLRLQEVTSQSGDE---------------------------------------------QKEERDTHTHTTDTAQTLSADTAEPTLENTAADEPMQTPSADAAEPLEPVTAAEPASPVTEDAAEQRQTSS----ADETPAQTLPKHTAETHTPTTVNPAEPTAESAQMEES---------------------------------------------------------------------------------------------DEPEPVQILSAGTAESAQTHAAEEPAQTHAADEAESAQTLTADTESAQTRNADLNEPVLKMNADQAEHVQTHS--------ADDAECVQTPTAET---------------------------------------MRIYNADADVPAQTIHADEAESVQTPT------------------------AETDEPVETADADTSEPAQTLTADEADSAQTHIADTEP-------------------------------AQTLTADTVKTLNADEAEPVQTVDQDETVQMVDADEVESAQTLT----------------------------TETDGTAEMDNAEPAHTLTANEAEHELTADEAKSAQTLTADEADSAQTLTADEAKS-------------------------------AQTLTADEANSAQTLTADEAESVQTLTADEADSAQTLTVDEAK---------------------------------------------------------------------------------------------------------------------------------------SAQTLTADEADSAQTLTADEADSAQTLTADEAKSAQTLTADEAKSAQTLTADEAEHEQTLNADEA--------DSAQTLTADEADSAQTLTADEADSAQTLTADEADSAQMLTADEAESAQMLTADEAEHG------------------------------------------------------KTLNANEAESAQMLTADEIKTDRMLAADTDEPAQTLTAETAAP---------------------------------------------------------------------------------------------------------PSSSGEQESAAAAAEDEDGD------------------------DDEEDTRVSRTPRRGRSSRAAEAPQRETRSASQPKEVEP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AVEEEPKEQSRRGR--------------------RSAAQTRDTPAVKPALKRKRSDEELKEDPEPSAKHRRDAVSPAGDQDASKASDEEEERKEEEEEETTEDQQRK------PARRGRPSK-------------------------------ASSATDDSDTGASEKRDGEKEEDEEEEKKSR--------ATTRAASRLEAERNKPSKPSTRALSKLSKEENTPHTRSVRG-------------------------------------------------------------------------------RKRDPSPPVSRTRGGQKSEDPAAKRAKR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KHZ9-1", "uniprot_id": "A0A0B4KHZ9_DROME", "id": "A0A0B4KHZ9-1", "name": "", "aln": "-------------------------------------------------MDDFIKTLIAEVKSQGVFDEFRFNCCLADVDTKPAYQNVRTQVETAVNDFLAKQQWTPETNKVQLRERLRKHLMDSDVLDKGVDQIVDQVVNPKVATIFEPKIESIVYKYLG---------------------------ITPPARPTMLSAPPLPPFGAHLNGSSLLN----------------------------------------------------------------------------------------------VETTVGLLPTDLEQISPDSDRATVKSESRDDELPPGVDDEDTSPSYELVSER--------------------KTLAIKEELNNVSLNNSDSVNGVSQASQLSQVSSDSRLTMASSTESMVDSHQHTAAHNSGEPENICEEAQMPKFSENSWDASAGTGRSEGRQLHFDIKQDAITFEG----TERKNSVSETTSTGLQILSIEDEIMSEVKANIDDANNASIESIAPEP------------------------VQVPAPPKVNPPPPPRPASPKVEPPPPAPPGVESPPGPQPPASPRFDP-------------------------------------PPPHTIEPPPPPAPPTLVP--------------------------------------------------------PPPPAPPTIKPPPPPAPPTVEPPPPPPPAPPTVEPPPPPPPAPT-----------------------KVEPPPPPAPAEVEPPPPPAPTELEPPPPPAPPKVELPPPPAPPKAEAAITPRRAKGSNG----------------------------------------------------------------------------------FITELAVTPKESETRDKPHNVNTDVKEDEQPATTEDKQDKPLELG---------------------------LDAPKDAVSTASESTESPTSTSSQSKSHSKSRDKEKEKD--------------RRHHRHSDDKHRRRSTDRDRDRSRD--------------------------KSHSKHSSSSSSKHSSSNSSSSKHKSSSSKNDKSSSSSSSRSNRESSSSKRSGTTSSSRHESSSHKKHKSSSSSSRSERDKGKEKDKEREKDSQSRSHHSSSSSSSSSRRKDHDRGRD---------------------------------------------------------------------------------------------RDRNKSNTSGSAENKAIHDDHSESKEKYKQRRGSDSNDEGKPPSSGGPAKNSQPEDSAATMKSDAPVENANGTNGNSNGSTN----------------------------------------------------------------------------------------------------------------GACDNVSGVVIVSDILQQSTSSFVELTAGSQSHDRAESSKHEPED--------------------------------------------------------------------------------IDGKEADNQPEKTELEARQ------------------------------DECASQNEVPTVEPQTLADSVPDLPAKESMDTLE-----------------------------------DEKVETNVEENKSEEESKPENPPEECVDEPAQVGDVED----------------------------------------PPQDADKPATPVPISNEQSDEFSADFVTHFEENTDEFRTRLQLIN-------------------------------------------------QLIEDRKNLLNRLSEDGTQEEAVDIR----------------------------------------------------------------------------------------------------------------------------------------------ALRRSLSKRRRSSMQEQHRVERETTPPQPRSPSSSSTAGSPAKRLRQDEPKSS---------------PTPSDASINSKENEALEKQEHADALSARRLSKKLCQQQRYTNDDLYKPRPILSQRSRRRGLDSIL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: :: .:*::*:**:** *********** ::* :*:. * :.**.: *:*. ** ***: :*: : .*.:*:.*:*:*: ***:**: *.*::* * .:*. ..* . : : : . . . . : .. .. .. . ..: . .. . . : .:. : : : :: ** :** ::*::: : * :** .: *. . *.. .. :.: : : . :. : .. * : : .: :. :*:.*::: .. * : * :.* : : . . : ** . : * : : :. : . : .: .. : . : . : .* . : : . : : *:. :. *: . . : :. . :: . : : * * : . . .:. * : . * . :.* . : . :* . ... . . .. .. *: :. ... . :. .. : . * . . :.. . : . . : :* : . . . . . .: * : : *. . . . : :: . : :. : : * . .. . .. * ::. .. : : : :.. .: . : . * . : :* : . . :: :: . :: . : :: .:. . : : . . * ::.. * : :. * . . : : . .:. ", "identical_positions": 86, "similar_positions": 301, "identity": "2.76%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111031-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NYQ8-1", "uniprot_id": "FAT2_HUMAN", "id": "Q9NYQ8-1", "name": "Protocadherin Fat 2", "aln": "MTIALLGFAIFLLHCATCEKPLEGILS--SSAWHFTHSHYNATIYENSSPKTYVESFEKMGIYLAEPQWAVRYRIISGDVANVFKTEEYVVGNFCFLRIRTKSSNTALLNREVRDSYTLIIQATEKTLELEALTRVVVHILDQNDLKPLFSPPSYRVTISEDMPLKSPICKVTATDADLGQNAEFYYAFNTRSEMFAIHPTSGVVTVAGKLNVTWRGKHELQVLAVDRMRKISEGNGFGSLAALVVHVEPALRKPPAIASVVVTPPDSNDGTTYATVLVDANSSGAEVESVEVVGGDPGKHFKAIKSYARSNEFSLVSVKDINWMEYLHGFNLSLQARSGSGPYFYSQIRGFHLPP-SKLSSLKFEKAVYRVQLSEFSPPGSRVVMVRVTPAFPNLQYVLKPSSENVGFKLNARTGLITTTKLMDFHDRAHYQLHIRTSPGQASTVVVIDIVDCNNHAPLFNRSSYDGTLDENIPPGTSVLAVTATDRDHGENGYVTYSIAGPKALPFSIDPYLGIISTSKPMDYELMKRIYTFRVRASDWGSPFRREKEVSIFLQLRNLNDNQPMFEEVNCTGSIRQDWPVGKSIMTMSAIDVDELQNLKYEIVSGNELEYFDLNHFSGVISLKRPFIN-LTAGQPTSYSLKITASDGKNYASPTTLNITVVKDPHFEVPVTCDKTGVLTQFTKTILHFIGLQNQESSDEEFTSLSTYQINHYTPQFEDHFPQSIDVLESVPINTPLARLAATDPDAGFNGKLVYVIADGNEEGCFDIELETGLLTVAAPLDYEATNFYILNVTVYDLGTPQKSSWKLLTVNVKDWNDNAPRFPPGGYQLTISEDTEVGTTIAELTTKDADSEDNGRVRYTLLSPTEKFSLHPLTGELVVTGHLDRESEPRYILKVEARDQPSKGHQLFSVTDLIITLEDVNDNSPQCITEHNRLKVPEDLPPGTVLTFLDASDPDLGPAGEVRYVLMDGAHGTFRVDLMTGALILERELDFERRAGYNLSLWASDGGRPLARRTLCHVEVIVLDVNENLHPPHFASFVHQGQVQENSPSGTQVIVVAAQDDDSGLDGELQYFLRAGTGLAAFSINQDTGMIQTLAPLDREFASYYWLTVLAVDRGSVPLSSVTEVYIEVTDANDNPPQMSQAVFYPSIQEDAPVGTSVLQLDAWDPDSSSKGKLTFNITSGNYMGFFMIHPVTGLLSTAQQLDRENKDEHILEVTVLDNGEPSLKSTSRVVVGILDVNDNPPIFSHKLFNVRLPERLSPVSPGPVYRLVASDLDEGLNGRVTYSIEDSDEEAFSIDLVTGVVSSSSTFTAGEYNILTIKATDSGQPPLSASVRLHIEWIPWPRPSSIPLAFDETYYSFTVMETDPVNHMVGVISVEGRPGLFWFNISGGDKDMDFDIEKTTGSIVIARPLDTRRRSNYNLTVEVTDGSRTIATQVHIFMIANINHHRPQFLETRYEVRVPQDTVPGVELLRVQAIDQDKGKSLIYTIHGSQDPGSASLFQLDPSSGVLVTVGKLDLGSGPSQHTLTVMVRDQEIPIKRNFVWVTIHVEDGNLHPPRFTQLHYEASVPDTIAPGTELLQVRAMDADRGVNAEVHYSLLKG-NSEGFFNINALLGIITLAQKLDQANHAPHTLTVKAEDQGSPQWHDLATVIIHVYPSDRSAPIFSKSEYFVEIPESIPVGSPILLVSAMSPSEVTYELREGNKDGVFSMNSYSGLISTQKKLDHEKISSYQLKIRGSNMAGAFTDVMVVVDIIDENDNAPMFLKSTFVGQISEAAPLYSMIMDKNNNPFVIHASDSDKEANSLLVYKILEPEALKFFKIDPSMGTLTIVSEMDYESMPSFQFCVYVHDQGSPVLFAPRPAQVIIHVRDVNDSPPRFSEQIYEVAIVGPIHPGMELLMVRASDEDSEVNYSIKTGNADEAVTIHPVTGSISVLNPAFLGLSRKLTIRASDGLYQDTALVKISLTQVLDKSLQFDQDVYWAAVKENLQDRKALVILGAQGNHLNDTLSYFLLNGTDMFHMVQSAGVLQTRGVAFDREQQDTHELAVEVRDNRTPQRVAQGLVRVSIEDVNDNPPKFKHLPYYTIIQDGTEPGDVLFQVSATDEDLGTNGAVTYEFAEDYTYFRIDPYLGDISLKKPFDYQALNKYHLKVIARDGGTPSLQSEEEVLVTVRNKSNPLFQSPYYKVRVPENITLYTPILHTQARSPEGLRLIYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESKTKHVFTVRATDTALGSFSEATVEVLVEDVNDNPPTFSQLVYTTSISEGLPAQTPVIQLLASDQDSGRNRDVSYQIVEDGSDVSKFFQINGSTGEMSTVQELDYEAQQHFHVKVRAMDKGDPPLTGETLVVVNVSDINDNPPEFRQPQYEANVSELATCGHLVLKVQAIDPDSRDTSRLEYLILSGNQDRHFFINSSSGIISMFNLCKKHLDSSYNLRVGASDGVFRATVPVYINTTNANKYSPEFQQHLYEAELAENAMVGTKVIDLLAIDKDSGPYGTIDYTIINKLASEKFSINPNGQIATLQKLDRENSTERVIAIKVMARDGGGRVAFCTVKIILTDENDNPPQFKASEYTVSIQSNVSKDSPVIQVLAYDADEGQNADVTYSVN-PEDLVKDVIEINPVTGVVKVKDSLVGLENQTLDFFIKAQDGGPPHWNSLVPVRLQVVPKKVSLPKFSEPLYTFSAPEDLPEGSEIGIVKAVAAQDPVIYSLVRGTTPESNKDGVFSLDPDTGVIKVRKPMDHESTKLYQIDVMAHCLQN-TDVVSLVSVNIQVGDVNDNRPVFEADPYKAVLTENMPVGTSVIQVTAIDKDTGRDGQVSYRLSADPGSNVHELFAIDSESGWITTLQELDCETCQTYHFHVVAYDHGQTIQLSSQALVQVSITDENDNAPRFASEEYRGSVVENSEPGELVATLKTLDADISEQNRQVTCYITEGDPLGQFGISQVGDEWRISSRKTLDREHTAKYLLRVTASDGKFQASVTVEIFVLDVNDNSPQCSQLLYTGKVHEDVFPGHFILKVSATDLDTDTNAQITYSLHGPGAHEFKLDPHTGELTTLTALDRERKDVFNLVAKATDGGGRSCQADITLHVEDVNDNAPRFFPSHCAVAVFDNTTVKTPVAVVFARDPDQGANAQVVYSLPDSAEGHFSIDATTGVIRLEKPLQVRPQAPLELTVRASDLGTPIPLSTLGTVTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTEVLQLATLTRPGAEK--TGYRVVSGNEQGRFRLDARTGILYVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVMVNITDVNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLNSDITYSLIGGNQLGHFTIHPKKGELQVAKALDREQASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRFFQLNYSTTVQENSPIGSKVLQLILSDPDSPENGPPYSFRITKGNNGSAFRVTPDGWLVTAEGLSRRAQEWYQLQIQASDSGIPPLSSLTSVRVHVTEQSHYAPSALPLEIFITVGEDEFQGGMVGKIHATDRDPQDTLTYSLAEEETLGRHFSVGAPDGKIIAAQGLPRGHYSFNVTVSDGTFTTTAGVHVYVWHVGQEALQQAMWMGFYQLTPEELVSDHWRNLQRFLSHKLDIKRANIHLASLQPAEAVAGVDVLLVFEGHSGTFYEFQELASIITHSAKEMEHSVGVQMRSAMPMVPCQGPTCQGQICHNTVHLDPKVGPTYSTARLSILTPRHHLQRSCSCNGTATRFSGQSYVRYR---APAARNWHIHFYLKTLQPQAILLFTNETASVSLKLASGVPQLEYHCLGGFYGNLSSQ-RHVNDHEWHSILVEEMDASIRLMVDSMGNTSLVVPENCRGLRPERHLLLGGLILLHSSSNVSQGFEGCLDAVVVNEEALDLLAPGK-TVAGLLETQALTQCCLHSDYCSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCE---QGRENCTFAPCLEGGTCILSPKGASCNCPHPYTGDRCEMEARGCSEGHCLVTPEIQRGDWGQ--------------QELLIITVAVAFIIISTVGLLFYCRRCKSHKPVAMEDPD--LLARSVGVDTQAMPAIELNPLSASSCNNLNQ-----PEPSKASVPNELVTFGPNSKQRPVVCSVPPRLPPAAVPSHSDNEPVIKRTWSSEEMVYPGGAMVWPPTYSRNERWEYPHSEVTQGPLPPSAHRHSTPVVMPEPNGLYGGFPFPLEMENKRAPLPPRYSNQNLEDLMPS-RPPSPRERLVAPCLNEYTAISYYHSQFRQGGGGPCLADGGYKGVGMRLSRAGPSYAVCEVEGAPLAGQGQPRVPPNYEGSDMVESDYGSCEEVMF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5F226-1", "uniprot_id": "FAT2_MOUSE", "id": "Q5F226-1", "name": "Protocadherin Fat 2", "aln": "MTLVLLGVAMVLLHRAACEKPLEETIT--PLTWRFTHSLYNATIYENSAPKTYVESPVKMGMYLAEPHWVVKYRIISGDAAGVFKTEEHVVGNFCFLRIRTKSSNTALLNREVRDSYTLVVQASDKSLEFEALTQVVVHILDQNDLKPLFSPPSYRFTISEDRPLKSPICKVTATDADLGQNAEFYYAFNARSEVFAIHPTSGVVTVAGKLNVTWRGKYELQVLAVDRMRKISEGNGFGNLAPLVIYVEPVHRKPPVITLVVLNPPEGDEGDIYATVTVDTNGSGAEVDSLEVVGGDPGKYFKVLKSYAQGNEFNLVAVRDINWAEHLHGFNISLQTHSRSRFPSRSIIRAFHLPP-YTLANLRFEKAVYRVKLSEFSPPGSRVALVRVTTALPTLRYALKPSSGSTVFKLNARTGLITTTKPVDFHEQNQYQLHVKTSLGQATTTVIIDIVDCNNHAPVFNRSSYEGTLDENIPPGTSVLTVTATDQDHGDNGHITYSIAGPKAVPFSIDPYLGVISTTKSMDYELMKRIYTFRVRASDWGSPFRQEKEVSVSLRLKNLNDNQPMFEEVNCTVSLRQDAPVGKSIMAVSAIDMDELQNLKYEIVSGNEQDYFHLNHFSGVISLKRSFMN-LTAVRPTVYSLKITASDGKNYASPTTLKVTVVKDPRSEVPVQCDKTGVLTHITKTILQSAGLQGQEMGEEDFTSLGNYQINHHAPQFEDHFPQSIDILEQVPVNTPLAHLAATDPDPGFHGRLVYVIADGNEEGCFDIELETGLLTVAAALDYETTSFYVLNVTVYDLGTPPKSSWKLLTVTVKDWNDKPPRFPPGGYQLTISEDTEVGTTVAELKTRDTDSEDNGRVRYTLLTPTEKFSLHPLTGELVVTGQLDRESEPQYILKAEARDQPTKGHQLFSVTDVIVTLEDINDNPPQCITEHSSLKVPEDMPLGTVLTFLDASDPDLGPAGEVKYILVDDVHGTFRVDPMTGALSLEKELDFERRAGYNLSFWASDSGRPLARRTLCHVEVLVMDVNENLHSPHFSSFVYQGQVQENSPAGTQVMVVTAQDDDSGLDGELQYFLRAGTGLEAFSINQDTGMLETLAPLDREFTPYYWLTVLAVDRGSVPLSAVTEVYIEVTDINDNIPSMSRPVFYPSVKEDAPLGTSVLQLEAWDPDFSSQGKLTFNLTSGNHMGHFIVHPFTGLLSTAKQLDRENKDEYVLEVTVQDNGDPPLRSTSRVVVCVLDVNDNSPMFSHKLFNVRLSERLSPLSPEPVYRLVASDPDEGLNGSITYSIEESDEESFRIDPVTGVVSSSSTFAAGEYNILTIKATDSGQPALSTSVRLHIEWIPQPRPSSIPLSFDESHYSFAVMETDPVNHMLGVISVEGRPGLFWFHISDGDKDMDFDIEKTTGSIVIARPLDTRRKSSYNLTVEVTDGFHTIATQVHILMIANINHHRPQFLQDHYDIRVPQDTLPGVELLRVQATDQDHGKGLIYTIHSSRDPGSANLFQLDPSSGVLVTVGTLDLHSGPSQHILTVMVRDQEMPIKRNFVWVTIHVEDGNLHSPHFTQPRYEANVPDTTTPGTELLQVRAVDADRGANAEVHYSFLKG-NSEGFFNIDSLLGIITVAQRLDHVHLNRHALTVKAEDQGSPQRHDLAMVVVHVHPSDSSAPIFSKDEYFIEIPESVPIGSPILLISAASSSDVTYELREGNKNSVFSMNSYSGLISTQKRLDHEKVSSYQLKIRGSNMAGVFTEVVALVYIIDENDNAPAFLKSTFVGHISEAAPLHSLILGEDNSPLVIRASDSDQEANSLLVYKILEPEALKFFKIDPSMGTLTITSELDYETTPLFQFSIYVHDQGTPILFAPRSARVIIHVRDVNDSPPRFSEQIYEVAVVEPIHPGMELLTVQAEDNDSKVTYSIKTSNTDEAVTIHPITGQISVVNPAALRLFPKLNIRAFDGLYQDTAVVKISLTQALDKSLQFDQDIYRARVTENTPHSNVLVILGVHGNHLNDTLSYFLLNGTDLFHMVKSAGVLQTRGVTFDREQQDTHEVAVEVRDNRVPRRVAQALVRVSVEDVNDNIPEFQHLPYYTVIQDGTEPGDVLFQVSATDKDLGANGTVTYGFAEDYAYFRIDPYVGDISLKKPFDYQALNKYHLRVTARDAGTPPLQTEVEVHVTVRNKSNPLFQSPYYKVKVPENITLYTPILHTQARSPEGLRLIYNIVEEEPLMLFTTDFKTGVLTVTGPLDYESKNKHVFTVRATDTALGSFSEATVEVLVEDINDNPPTFSQLVYSTSVSEGSPAQTPVIQLLASDQDSGQNQDVSYQIVEDGSDVSKFFRINGSTGEMFTIQELDYEAHQHFRVKVRATDRGDPPLTGETLVVVNVSDINDNPPEFREPQYEANVSELATCGHLVLKVQALDPDIGDTSRLEYLILSGNQDRHFSINSTSGIISMFNLCKKQLDSSYNLRVGASDGVFQATVPVYINTTNANKYSPEFQQNVYEAELAENAKVGTKVIELLAIDKDSGPYGTVDYTIINKLAGERFFINPSGQITTLQKLDRENSTERVIAIKIMARDGGGKVAFCTVKIILTDENDNAPQFKASGYTVSIPSNVSRDSPIIQVLAYDADEGRNADVTYSVDSTEDLAEEIIEVNPTTGVVKVKESLVGLENKAVDFNIKAQDGGPPHWDSLVPVRLQVVPNEIPLPKFSEPLYTFSASEDLPEGSEIGSVKAVAAQDPIIYSLVQGTTPESNSDDVFSLDQDTGVLKVKKAMDHESTKWYQIDLMAHCPHEDTDLVSLVSVNIQVEDVNDNRPVFEADPYKAFLTENMPGGTTVIQVTANDQDTGSDGQVSYRLSVEPGSNIHQLFAVDSESGWITTLQELDCETQQTYRFYVVAFDHGQTIQLSSQALVEVSITDENDNPPRFASEDYRGSVVENNEPGELVATLKTLDADISEQNRQVTCYITEGDPLGQFSISQVGDEWRITSRKTLDREHIAKYLLRITASDGKFQASVPVEVFVLDINDNSPQCSQLLYTGKVREDVTPGHFILKVSAIDVDMDTNAQITYSLHGPGAQEFKLDPHTGELTTLSVLDRERKDVYNLVAKATDGGGQSCQAEVTLHIEDVNDNAPRFFPSHCAVAVFDNTTVKTPVAVVFARDPDQGVNAQVVYSLTDSADGQFSIDATSGVIRLEKPLQVRSSSAVELTVRASDLGTPIPLSTLGTVTVSIVGLEDYLPIFLNSEHSTQVPEDALIDMEVLYLATLTRPGSEK--TGYHITGGNEQGKFRLDAHTGILYVNGSLDFETNPKYFLSIECSRKSSSSLSDVTTIVINVTDVNEHHPRFTHDLYTVRVLENAIVGDVILTVSASDDDGPVNSVITYSLVGGNQLGHFTIDPKKGKLQVAKALDWEQTPSYSLRIRATDSGQPPLHEDTEVAVEVVDVNDNPPRFFQLNYSTAVQENSPIGIKVLQLILDDPDSPQNGPPYFFRITEGNTGSVFRVTPDGWLVTAGSLSRRAQEWYQLHIEVSDSGLPPLSSSTLVRVHITEQSRYPPSTLPLEIFITKGEEEFQGGMVGKIHATDRDPQDTLTYSLDREGSLGKYFTVGASDGKIIASQGLPRGRYLFNVTVSDGTFTTTTGVHVHVWHMGQEAPQQAVWLGFHQLTPEELVSDHWRNLQRFLSNILDIKRANIHLASLQPAEVTAGVDVLLAFEGHSGTSYDLQELASAIAHSAKEMEHSVGIQMRSALPVVPCQGPSCQDQTCQETVSLEPRVGPSYSTARLSILTPRHHLGKNCSCNGTTWRFSGQSYMRYR---PLEAQNWQIHFYLKTLQPWALLMFTNETASISLKLANGFLHLEYRCPGGFYGNLSSH-RPVNDGQWHSMLLEERDTSVHLLVDITDNTSLVIPEECQGLRTERHLLLGGLVPSNPSSNVSLGFEGCLDAVVVNSERLELLGHRK-KMAGYLETWALSQCCWPGTTCSQNPCLNGGSCSPALGSGYLCRCPPLFSGRNCE---LGRENCTSAPCQEGGTCVSSPEGTSCSCPHPYTGDRCEMEARGCSGGHCLITPEIKRGDWGQ--------------QEFLVIIVALPLLIIATVGLLLYCRRCKSHKPVAMEDPD--LLARSIGVDTQASPAIELDPLNAGSCNDLNQ-----LEPSKTSVPNELVTFGPSSKQRPMVCSVPPRLPPAVVSSHPGHEPIIKRTWSGEELVYPSGAAVWPPTYSRKEHWEYPHPEAMQGPLPPSPRRHVSPAVMPDPAGLYGGFPFPLELENKRAPLPPRYSNQNLEDLIPP-RPPSPREHLLAPCLNEYTAISYYHSQFRQGGGGPCLAEGGYKGVSMRLSRAGPSYADCEVNGGPAPGRSQPRAPPNYEGSDMVESDYGSCEEVMF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FB42-1", "uniprot_id": "E7FB42_DANRE", "id": "E7FB42-1", "name": "", "aln": "MSFTDTAIILTVIAVLGTLTRCHGSLVKDSSLLRFTHHLYNASIYENSAPKTYVESSVRMGILLTDPFWNIKYKIVSGDDDGLFQTEKEDVGDFSFLRIITRSSNSAVLNREVRDIYTLTVEATESTFDNRARTKVLIQVLDTNDLKPLFYPASYHVVIKEDTPIKSSLVRVSATDADIGSNAEFYYSFTTRSHPFAVDPFTGTVTLVKRLDTSQRDRYDLTVLAEDRKKKISGVQKFGNVATVVVKIQKVEKNFTLISPTTAESLLTIDDKISVNIKMEPKEK-ENTASLSIVKGDPLNCFQIIPSAFYDGGFQLVSTKFIDWSQNPLGLNISLQAKDRSNPPLLTPIKTVHIPPPLQIKPLRFEQELYYVTLSEFSPPKTHVVRVSVGLSLKNTTFSIQENPDSYKFKISAKTGVIVTSQSLDFENRNHYEFDVTANDGEAVTRVIVDITDENDNAPSFTLPSYQASLPENVRIGTSVLSVSAIDVDKDNNGFVTYAIANTGPVPFSIDPLTGVISTSQEFDYELMKRWYHLRIWASDSGNPFNRVSECTVTITMTNVNDNVPVFERVACNASIPRDFAVGEIIAEISALDLDELQQIVYRIESGNDDGLFSIDPVSGIIKLAKAIPSNYKDTENSLYTLKITATDGTYIADPNTVTVSITDNGE-GAITHCEETGITRQLTEKLIESFRPSLNIKEEESIS--DVHIINQHSPKFVISTPGSIDIREDFALNRSVLQFNATDNDSGFNGKLVYSISSGNEDGCFTIDVNAGDLKVICALDREQKEFYILNITVYDLGYPQTSTWKLLAVNILDANDNPPLFSQSRYVVTIPENTEVDKSIFKVNAVDFDLDNNGAFKYSLFTFTDLFQIEEDTGVVKVIGPLDRETFRRYDLTIEARDQAKPDPQLFSFTDVVVVLEDINDNPPKFVPTVYKIKVPEDVPPGTVLLWVESFDLDLESGGVISYNLKNSESGTFFLDTSTGSLTLERELDFEKRQFYNLTVRAVDHGKPRSLSSSCFIEIEVLDVNENLNRPLFGEMVHTAAVMEDAKIGTSVLTLTAVDNDLGRDGVVRYYIHDGSGLGVFTVDEETGVIQTAGLLDREVVPHYWLTVYAKDLGTIPLVSWTEVYIEVWDINDNPPELSQPVYFGSVQENLPKDKSVLKVSATDMDKSSEGKLAFQILDSQRI-YFTIDSKTGVISTLSSLDREQKAEHIIEVMVSDKGEPPLSSTATVVIEVLDENDNSPQFSHKLFQIKLPERQSTAEPQDIYRMVARDDDVGPNGMITYSLEDNNEGRFDIHPDTGVVTARGQFVRGNYSILTIQATDQGNPPRMSKSRLHVEWLPQPEPSSDVLAFDEPPFNYVVMETDPVTDMVGIIRTEIPKNLLLFDIIGGDEEQDFYIEKNTGSIVKARRLNAGKKSHYNLTVRVTDGFQTITTQAYIQVVD-INEHRPMFLKSLYEVRVPEDTSPWKEILHISAHDADASSGLFYSIHSSLNPESLKYFHLDQRSGVLVLKEELDYET-ISTHTLIVMVRDDKIPIKKNFAKVVVHVEDCNDHIPSFLDTHYEGIISNLALTGTEVLRVKALDKDTGSNADIVYSFHSGGNVDGAFKIDQGTGSIRVSDALDRLPQEHYHLTVKATDQGFPQRSALCPVTITIKLSEFTPPRFSSKEYITEISEAMPPGSPVLSVSARCPSSVLYRINEGDPNGTFHININSGLLSVKNALDFEQHSSYHLQISATNTAGISSDAVVFVYVIDANDNAPVFHQDVYYGQISESAPVNSMVTGENNTPLVIKASDADKDTNALLVYQILEPAAHEVFKIDPSMGTISLKSLIDFEATPEFFFSVQVWDSGEPSLSASKPCKVIIRVLDFNDCPPKFVLPVYEIALTWPVFQDMKVIQVTAHDADSAVTYMILENSNKNAFKIDQSTGVISVNDSSELQSHNELKITAFDGLYKDTTVVKLNITNATKSSLKFEDRAHVATVLENSTSVKILVVLRATGTYLNEPLQFTVLNPHGKFAVIPSSGVLHTTGVPFDREEQDVYDVAVEVRDFRSPPRVDVTHVKVYIDDVNDNVPEILNLPKTLLISDETEPGDVLFQVLATDNDFGENGSIIFSLEDDFGLFRIDLYLGDVSLQRPLDFESMNKYVLTVLVSDDGQPSLSAIGTIYIQVQNRSHPIFQSMYYPLKLPENITPFTTILHVQARNPEGYRLIYNLEEDNASRLFNIDFKTGVLSVTDFLDFESETKHILTVRATDSVSGTFAEAKVEIDVEDINDNAPVFQNLSYVADVFEGLPIGTSVLQVSAVDRDADKNAEATYQLIDKES---HFFEIDPLSGVLVTTQVLDYESTQQFTLKVKATDKGVPPLSGEAHIIVNVIDVNDNPPDFSEPSYRASLDEMATCGNIVIKVQASDPDSKDD--LQYKILSGNEGRYFAINESSGLISFSNVCKRNLDPFYNLTVAVSDGVFQKTAPVNIDMTNGNKYSPYFTQNIYEADLAENAEVGTRVIRLAAIDPDDGPYGSVDYTIINKLADEKFAINEDGQIVTSQPLDRENPSQRVIAIKIMAKDGGGRVGFCTVKIILTDENDNVPQFKASEYDISIQSTVNKGSPVIQIMAYDADEGKNADVTYTVEEADEVTEDIIEVNPFTGVVSVKESLVGLENKIFNFKVKARDGGFPFYNSSVPVQVKVVPPEIILPRFTEPLYSFSASEDLPIGYEIGTVKADADMP-LIYSLVNGNTLDSNKELSFAIDKDGGTVVLQNNIDHEKTKMYKIDVIAQGNHNGTNVASLVSVHIEVQDVNDNKPMFEADTYKAFLAENLPSGTTVIQVTANDADANINGEVSYTLEPES-DDIGDMFAIDSQTGWITTLKEADSETKQLHRFFVVATDHGDALKQSASVLVEVTLTDENDNPPQFTEELYQGSILENSRPGENIVTLTTADKDVSAENRQIVCYITDGDPLGQFSVTAVGEEWTVISKSPLDREDKDKYTLKIIATDGRFQTSANVEVHVLDLNDNSPFCEQLQYTEAVMENSSSGKVILKISASDPDIGTNGQVSFTLHGPNADKFHLDPKTGELFTLAVLDREREKEYDLVVKATDGGGRSCQADVTLMVQDMNDNPPQFSTSHYEVTVFDNTTIRTPIAVIYAKDPDTGINSEVRYSLQGADSGFFSLDEISGVLRLERSLADETKSTYEMKVKATDRGLPRHLFSFAMITVHVVILSDYQPLFLSSEYSVQIAESSQVGSEVISVSALTKDATENEPVRYSIISGNEDGRFMINPVTGLLSVKAALDFERCREYYLSVEGAR-GKPLLSDIAMVIINITDVNDNPPVFNRSSYSTVIPEDISPGEMALQVRAIDLDGPPNNFIIYSIVSGDPKQQFSIDPRTGFITLRSMLDREEITHYSLTVQAADEGDPPLSSAVQVTVTVSDVNDNPPMFSKINHSLIVQEGEAVGSGILQLLVTDRDTPQNGPPFSFHIVSGNEDRSFHIDQGGLLSVSSQLRRRGKPQHLLKIQVTDSGHPPLSSICVVKINITEQSRYPPTVNPLEIFITTAGGPILKSVISKLHATDQDPQDVLSYKLVSEGQDKGLFSVDTVDGKIVVEKNLDPGLYHLNVSVTDGKFSIWAGVKVHVWAATQQNLDQGFTLQLAGISAEEFVSDHWRGLQRSLAQELNIPRQELHIASLQQQPNSVNTEVLLVRRAQDGSVKSVPVQR--LTGVLSTVEDTLGLNVLR-LKHDGCVGAGCPPRGCKNTVVMRQGRMSNYATARMNFITPQHSWESMCTCNESAVRFDGKGYLKYLYHMEEAKENFHLSLRLKTSAADGTVMATNASDWGTLELVDKELWLRYRCGNMLSAGLQVANYPVADGRWHHVSLDVNDTTLRLTIDSSHTNSVVLPQPCRLSHPGGALVLASSNP--NTDAERLGFTGCLESVHFNGEALRRQEGMTGAGAQAGKLFGIYQCCSDVEICASNPCENGGICAENSTGGFHCSCPSMYYGPHCQFIHLPDDPCSSKPCVDG-LCMPNNQGYICNCSTQIAGNRCPTSCAPNSCQDGFTCSMVANSVHCERTTYRSTYIPYVEIAEICAGVVGLVLLVIAFVCFRKHYVSKKKHKSGCVQDSNGYFPTLPKTMTKEAEISSPMDGMLIGSVGDLESSPFRSLKLREQRELGPQVGPRPQRPQGPVICSVAPNLPPPPSTSS-DNDSIMKNNWEHDYEVYP----ADPDYYGRPAVQEFPQFDIVES-------TYSNTSTESRRNSRFGGFPFPLDRADRRAPLPPCYSNQNLDDFLGPDGLPLPR----SQCPNEYTAISYYPTQHARSLDN---VSSGYKRLSVRLSVAQPSYADSTRPG------STRRTSRSYAGSDRVESDYGSCEEVMF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::. .. : :: . . : . :*** ***:*****:******* :**: *::* * ::*:*:*** .:*:**: **:*.**** *:***:*:******* *** ::*::.::: .* *:*::::** ******* *.**:..*.** *:**.: :*:*****:*.******:*.:**. **:.* :*.**:. :*:.: *.:::* *** ** :*** : **.:*.:*: :: . :: . *: .. . :. ..: ::.: . :. *:.:* *** : *: : * .. *.**:.: *:* : *:*:***::. * : *: .*:** : *:**: :* * ******* ::*. * * :: . : :: .. . **:.*:**:*.*:: :**.:: :*::.: :. *:* * *::**.* *::** *. .**:.:* **: *****:*:* * *:.:**.:**:**.. .:****** *:***:: :******* * :*: *** *.**.: .* :: : : *:*** *:**.* *. *: :* .**: * :**:*:****:: *.* ***: * :: .**:*.* :.: . . . : *:*****:**. *.*.*:.:::..: . . . *::**: ::*:.::. . : :*.:: . : **:::*:* * ***: *...:* .: :: *** *.**:*:*** *:.***:*** *::::* *.* ..** * ..**:**:****** * .*:****:*.: * **:.* *. . * :**.*:***..:: ::.: * * ::** .:*:*:: *: *.:. ** : * * ****: :* *. *****.. . ****.**:::.***:***.*: :. :*****:* **** :::: * ** ..* : * * :. *** :* **:* **:*****:* ***:. * * *:* : : *.:*: *:******: * *..:*: . * *:: **.*:.::* *:* * ** ::*::: *:** .*:::::**:::* . ****...:***** * * *::** : ******* * *** *.:*:.*:: *::*: * ..***::.* * * **:***:*:: ..: : .* :.. **::** ..****:* *:::** * *:*:*.* **: **: :** ***.* ******:::*.** *. .* :**:** * * * ** :***:*:.:* * *. ****:: . *. *:*.****:***.*:*. :. ***:**:* *.*** *:***. :.:.*******..*:*:* .* .*: *.* .**:: ** ***.***** ** *:: ::* *****.**** :**:**.:* :: **.*** **: *::***:** * *:*::.* * * ...*:*:**.* :* * . *:** ***** ** : * * * *****:::***:**. *.:**** * * * * : :**. :.: .***:*:*:*:* * * **:: **: .* * :* *:*: * * ::: **: : ***** *** ** *. * : : *: :.* **..**: **.*::* ***:* :** ..*.* *.:.**: :..* :* ***:*.:: **.*: ***:*:* .:* ** ::.:..* :** ***** * :..: *:***:**: *:: .::*.*:**:***:*:::*:****:**** * :.*********::: * :*:*: * * *.: * *.* * * *.:..:***:* *.**.**:* :**:*:. *:. .*::: * * * ** *.* * .. .:*..*. ** *** :.: * :*.* * ****:**::**:.:*:. ..**:*:: : * * ** : **:* . *.:**:.*.: :** . * :: *:***:* **.****:**.:::****** * * ** *:* ::***** *:: :** :*.* ********** ***:*:* **:: : : :*: **** *:**:**::*:*::::*** * * . * * *.*.: : : *:*:*:*:*** ** :::***** :*.***.***.*** *****: *::. **. *******:**. **:**:.**::******:. *:*:**.**: ***:***.*.*.:* * :.: ** * *.*:*: * *:*:.:* :.:**:::. * :**.*: :* : * * ****: *:* :**:* *:* ***:**: ::*** *:*****:* :*.*.*.:.*:****::*:**** *** * *:* *****:.*:* **.:**:**: *:**::**. *** *..*****: *.** *: **.***** * *::***:***** ***:** * *** *.****::*********.*:* ** .***.* * *****.::******:**:****:*.************** ****** * :** *.*.:.**:**::*******:******:*: .:::.:::**:** ****.**:*******: .:* :**:*** *.::* ***:::*** :: **:*:****:***.**** * *** *** * :*****.*.* :**.: *::* * *.: ::: :***.** *:**::*: :: *::.*****:*:* *****:*:****.***.*:**:* **:****** * *:. :*:*** *. :. .:: ::**:**::******:* *.** * ::*.*** ***:::: *:..**:*::******.*:*:.* *:**::**..*** :.**.* * *:* :***:.****:*******.:: **:** : *:..****. ** *:: *:**:**:*. **:.***:***** *.** ** * *: .*:.***:** * * .**.*::::****.*.:*:***:**** **:.*****:. ::**.*******:****::** ::*:***.*:* .** *:******::**:**::*:*** * *::* *** .: .* **:* :**:***:.* ...:. *:.*:*:* * * * ::. :** :* *.** *:**.:*:*.*:.*.: . **: :::**: .:*: . * : .***:*:* ::. **:* *:.:**** :*:**:* :* ... ***:: :::*:****:: * * :. *:. : *: *:: * * * * *** *. * **::.*: :*:*.*:.* : : . ** *: . *** ::*:*.*:*** . .:::: * ******* * ::*:* ***...:* :***:: * *:*:****: *:*..** . *:: .* * .: * **.: : *:*:.:*** ***** *::::****:*.*:. ******* . : .::.*:****:****.*:*.* * *:*.: ****:. :.* * * :**:*:**.*: :**:*:** *: :*.. : : ::.**:******.*** *:: *:* * ::*:**** ...:***. ..:.*: .. :: . :*.::*::: : * *. * : *::** : ..*:***:.::**:* *:** :: **.*:.*::* .*::: : *** . . :: ** : :*:*.. *.*:* . : ..*. * * .** : :: *::::* :* ..*:*:*: *: :. *:*.. :. ** ***::* .* * * . * : .: *** *:.*.* *** *: .*: * **. : * :*: : *: ** :* *: . :* *.*. :*:** .. * . : . : .. : *: *.: :::*: * : : *.**. .::*.: : : . : .:* : :: : .* .:*:. : : . * *. * *::***.*.***. .* .::.::*..*. : *** . * *.* *:*: : :. : .. . . . :*******: ::****** ******:*:: . * ** : * ********* :*. :. .. ...*** :.:*** * **** . * . *.. .* *** *************", "identical_positions": 1883, "similar_positions": 1407, "identity": "42.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111031-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2T4-1", "uniprot_id": "FIBIN_RAT", "id": "Q5U2T4-1", "name": "Fin bud initiation factor homolog", "aln": "------------------MMFTKLIWMGFFCHLCRGYFDGPLYPEMSNGTLHHYFVPDGDYEENDDPEKCQLLFRVSDRRRCSQGEGGQASSLLSLTLREEFTVLGRQVEDAGRVLEGISKSISYDLDGEESYGKYLRRESHQIGDAYSNSDKSLTELESKFKQGQEQDSRQESRLNEDFLGMLVHTRSLLKETLGISVGLRDKYELLAHTIRSHGTRLGRLKSDYLEGGGQKMG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CQS3-1", "uniprot_id": "FIBIN_MOUSE", "id": "Q9CQS3-1", "name": "Fin bud initiation factor homolog", "aln": "------------------MVFPKLIWMGFFCHLCRGYFDGPLYPEMSNGTLHHYFVPDGDYEENDDPEKCQLLFRVSDRRRCSQGEGGQASSLLSLTLREEFTVLGRQVEDAGRVLEGISKSISYDLDGEESYGKYLRRESHQIGDAYSNSDKSLTELESKFKQGQEQDSRQESRLNEDFLGMLVHTRSLLKETLDISVGLRDKYELLAHTIRSHGTRLGRLKSDYLEGGAQKTG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TAL6-1", "uniprot_id": "FIBIN_HUMAN", "id": "Q8TAL6-1", "name": "Fin bud initiation factor homolog", "aln": "------------------MVFLKFFCMSFFCHLCQGYFDGPLYPEMSNGTLHHYFVPDGDYEENDDPEKCQLLFRVSDHRRCSQGEGSQVGSLLSLTLREEFTVLGRQVEDAGRVLEGISKSISYDLDGEESYGKYLRRESHQIGDAYSNSDKSLTELESKFKQGQEQDSRQESRLNEDFLGMLVHTRSLLKETLDISVGLRDKYELLALTIRSHGTRLGRLKNDYLKV------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB12ZRE6-1", "uniprot_id": "A0AB12ZRE6_DANRE", "id": "A0AB12ZRE6-1", "name": "", "aln": "MWTSPLSGRSDLRRGQKRSIMLPFALGLFLLPLCGAVYEGPLLPEMSNGTFHHFFVPDGDYEETEDPEKCQMLFKWIDRRPCPLEEDRDT------VIREDFVIVKQQIEDAARVLETLGKSISFDLDGEDSYGKYLKREIEQIGEAFTNVEKSLLELESKFKQSQETEQREESEFSSNFIKPVYDVRETLQETLDISSGLKDKHELISLIVRNHGSRLSRLKNDYLNV------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : *: ** . ::*** *******:**:*********.:******:**: *:* *. *. :. .:**:*.:: :*:***.**** :.****:*****:******:** .***:*::* :*** ********.** :.*:**.:..:*: : ..*. *:***.** **:**:**:: :*.**:**.***.***: ", "identical_positions": 110, "similar_positions": 63, "identity": "46.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111031-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M0A0-1", "uniprot_id": "F1M0A0_RAT", "id": "F1M0A0-1", "name": "Anoctamin", "aln": "------------------MVHHSGSIQSFKQQK-GMNISKSEITTEASLKPSRRSLPCLAQSYAHSKSLSQSASLFQSTESESQAPTSVTFLSADKPEHVTSEESRKDSTLKCSFADLSEFCLALGKDKDYMDESEHANYDRSRLLNDFVTKDKPESKTKLSKNDMNYIASSGLLFKDGKKRIDYILVYRKTNIQYDKRNTFEKNLRAEGLMLEKEPAVANPDIMFIKVHIPWDTLCKYAERLNIRVPFRKKCYYTDQKNKSM-SRVQKYFKRIKKWMSQNPMVLDKSAFPELEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYENGISKVG-----------------------------IRKLINNGSYIAAFPPHEGAYKSSLPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAVVGLCVFFYGLVTMNESQVSQEICKATEVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEE---------ETLRPQFEAKYYRMEIINPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAVFAVVVYRLVVMEQFASFKWNFIKQHWQFATSGAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFERWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRGIQDAS----IPQWENDWNLQPMNIHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVKQNENCLKGYVNNSLSFFDLSELGIG--KSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDIPKGLRERIRREKYLVQEMMYEAELEHLQQQRRKSGQPIHHEWP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AHL1-1", "uniprot_id": "ANO3_MOUSE", "id": "A2AHL1-1", "name": "Anoctamin-3", "aln": "------------------MVHHSGSIQSFKQQK-GMNISKSEITTEASLKPSRRSLPCLAQSYAHSKSLSQSASLFQSTESESQAPTSVTFLSADKPEHVTSEESRKDSTLKCSFADLSDFCLALGKDKDYLDESEHANYDRSRLLNDFVTKDKPASKTKLSKNDMSYIASSGLLFKDGKKRIDYILVYRKTNIQYDKRNTFEKNLRAEGLMLEKEPAIANPDIMFIKIHIPWDTLCKYAERLNIRVPFRKKCYYTDQKNKSK-SRVQNYFKRIKKWMSQNPMVLDKSAFPELEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYENGISKVG-----------------------------IRKLITNGSYIAAFPPHEGAYKSSLPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRMYFGEKIGLYFAWLGWYTGMLIPAAVVGLCVFFYGLVTMNESQVSQEICKATEVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEE---------ETLRPQFEAKYYRMEVINPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAVFAVVVYRLVVMEQFASFKWNFVKQHWQFATSGAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFERWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRGIQDAS----IPQWENDWNLQPMNIHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVKQNENCLKGYVNNSLSFFDLSELGMG--KSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDIPKGLRERIRREKYLVQEMMYEAELEHLQQQRRKSGQPIHHEWP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYT9-1", "uniprot_id": "ANO3_HUMAN", "id": "Q9BYT9-1", "name": "Anoctamin-3", "aln": "------------------MVHHSGSIQSFKQQK-GMNISKSEITKETSLKPSRRSLPCLAQSYAYSKSLSQSTSLFQSTESESQAPTSITLISTDKAEQVNTEENKNDSVLRCSFADLSDFCLALGKDKDYTDESEHATYDRSRLINDFVIKDKSEFKTKLSKNDMNYIASSGPLFKDGKKRIDYILVYRKTNIQYDKRNTFEKNLRAEGLMLEKEPAIASPDIMFIKIHIPWDTLCKYAERLNIRMPFRKKCYYTDGRSKSM-GRMQTYFRRIKNWMAQNPMVLDKSAFPDLEESDCYTGPFSRARIHHFIINNKDTFFSNATRSRIVYHMLERTKYENGISKVG-----------------------------IRKLINNGSYIAAFPPHEGAYKSSQPIKTHGPQNNRHLLYERWARWGMWYKHQPLDLIRLYFGEKIGLYFAWLGWYTGMLIPAAIVGLCVFFYGLFTMNNSQVSQEICKATEVFMCPLCDKNCSLQRLNDSCIYAKVTYLFDNGGTVFFAIFMAIWATVFLEFWKRRRSILTYTWDLIEWEEEE---------ETLRPQFEAKYYKMEIVNPITGKPEPHQPSSDKVTRLLVSVSGIFFMISLVITAVFGVVVYRLVVMEQFASFKWNFIKQYWQFATSAAAVCINFIIIMLLNLAYEKIAYLLTNLEYPRTESEWENSFALKMFLFQFVNLNSSIFYIAFFLGRFVGHPGKYNKLFDRWRLEECHPSGCLIDLCLQMGVIMFLKQIWNNFMELGYPLIQNWWSRHKIKRGIHDAS----IPQWENDWNLQPMNLHGLMDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPLPARATDIGIWLGILEGIGILAVITNAFVIAITSDYIPRFVYEYKYGPCANHVEPSENCLKGYVNNSLSFFDLSELGMG--KSGYCRYRDYRGPPWSSKPYEFTLQYWHILAARLAFIIVFEHLVFGIKSFIAYLIPDVPKGLHDRIRREKYLVQEMMYEAELEHLQQQRRKSGQPVHHEWP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TLC9-1", "uniprot_id": "A0AB32TLC9_DANRE", "id": "A0AB32TLC9-1", "name": "Anoctamin", "aln": "MSPAFIFCWTPGSLSGIIMVHHSGSIQSFKQQKAGMHTSISEILKEKTLKSSRRSLPCLAQSQTHPENLNHFLSVPLSPGPKSYTHSSSVSASCTHITPPATDTGQD-----------------VYTEERETGGFEPKTDETLLVQQKPVSRGKLEARTDSVKG-KNLETPSGLMFRDGKKRIDYILVYKKSSPQVEKRCTFERNLRAEGLMLEKEPSLTNSDIMFVKIHAPWDTLCKYAEQMNIRMPFRKKCYFTDWKKKAMGSRFQLRFRQLKSWLPRNPMKLDKEALPDLVETDCYTAPFCRARMHHFTINNRETFFSNSTRSRIVHHVLQRTKYEDGKSKMAPPLCCLNLLYYYGQHERLLIGQSGSSWEGINRLLGNSTYEAAFPPHEGCYKSRHPIKTHGAQNHRHLLYERWARWGIWYKYQPLDLIRRYFGEKIGLYFAWLGWYTGMLIPAALVGLFVFLYGLFTMDSSQVSKEICEANTTVMCPMCEGNCSSWTLSDSCVYAKVTHLFDNGGTVFFAIFMAIWATVFLEFWKRRRAELTYDWDLIDWEEEECKPCVMVCSEELRPQFEAKYSRKERVNPISGKPEPFQPLTDKLSRLMVSVSGIFFMISLVLTAVFAVVVFRLIAMEKFVSFQWEFVKKNWQFATSGTGVCINFMIIMSLNVVYEKVAYLLTNLEHPRTESEWENSFALKMFLFQFVNLNSSTFYIAFFLGRFAGRPGDYNKLFNRWRMEECHPSGCLIDLCLQMGVIMVLKQIWNNFMELGYPLLQNWWSRRKMKRAGEQSNSKEELPQWDRDWNLQPMNAHGLVDEYLEMVLQFGFTTIFVAAFPLAPLLALLNNIIEIRLDAYKFVTQWRRPMPARATDIGIWHGVLEGIGVVAVITNAFVIAITSDYIPRFVYAIKYGPCVDKGYRHEKCLRGYLNNSLSVFDMGELRNGSYENQYCRYRDYRAPPWSPEPYEFTLQFWHVLAARLAFIIVFEHLVFGIKTFIAHMIPDMPKDLCDRMRREKYLMQEMVYEAELEHLQKERKKNGKRYHHEWP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *************** **: * *** .* :**.*********** ::.:.*.: *: *. .:* : :* . * : :: .:. : .:: . * . : : :. * :.* :*. *. . :.** :*:************:*:. * :** ***:*************:::..****:*:* **********::***:*******:** :.*: .*.* *:::*.*:.:*** ***.*:*:* *:****.**.***:*** ***::*****:******:*:*:*****:* **:. *.:*: *.:* ********.*** ******.**:************:***:******* ************************:*** **:***.**:.****:***:*. ..***:*: *** *.***:*****:*****************************: *** ****:***** * ********* : * :***:*****.** :**::**:*************:****.***:**:.**:*.**:*:*:*: ******.:.*****:*** **:.***:********:************************** **********.*:**.*****:***:********************.***************:******:*:**. .::. :***:.******** ***:*************************************************:********** *:*****::********************* *****.:: *:**:**:*****.**:.** * :. ********.****.:*******:**:*******************:***::***:**.* :*:******:***:*********::*:*.*: *****", "identical_positions": 674, "similar_positions": 194, "identity": "64.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111102-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3U2K0-1", "uniprot_id": "F193B_MOUSE", "id": "Q3U2K0-1", "name": "Protein FAM193B", "aln": "MTRRRSRPSGGAGRRERARAAGLQKPQAPEPQPPPPSLEAGAGAGPPEVPAELDCDGPREEEEPKLAPGPQVPPTSSQSVQTCCLLCHRERKGWEEGPSQNGLVLQGEKLPP-------------------DFMPKLVKNLLGEMPLWVCQSCRKSMEEEERQTGGDHAVAISLSHTS-CKSQSCGG--------DSHSSSSSSS--------SSSSSSSS-CHGNSGDWDPSSFLS---------------AHKLSGLWNSPHSSGAVPGSSLGSP-----------------------PAILGEAFPVSEHHQHSDLTAPPNSPTGPPPHPASLIPS--------HPGSFSS--ASYPPPLPTTPVAPFPAQASECPMAAATATHPSGPCQSPHPPSTSMPLLKMPPPLSGCSHPCSGHCSGHCGGPLLPPPSSQPLPSTHSRDPGCKGHKFAHSGLAC------EADEGLGEEEDSSSERSSCTSSSTHPRDGKFCDCCYCEFFGHNAPLAAPTSRNYTEIREKLRSRLTRRKEELPMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKARLATEALKQVNRVSGS-------QEPRPARERLLEWPDQELDRVNSFLSSRLQEIKSTVKDSLCASLSMCELSVESSGF-KEGTVEA--QTLTPSDLSGSSQKRPDINLDLSPLTLGSPQSHTLQAPSEPVPPWAERRDPHPPPWTEVRGPPPG-IPENGLVRRLNTVPNLSRVIWVKTPKPGNPSSEE-SSKEVPSCKQELSEPVA-TGGKPKKSKRQGSQAKKTLASPAPWSPANLEASGAKSQVSSPKQPSKGSEPAKVGSGAEPGEGSPGSRPGPIQADSPKTDK-KGSSWQNWPGGAKARTLEQESEQTPGPARPQSLSQGKGRSRRSRNKQEKSASSLDDVFLPKDLDGVEMDETDREVEYFKRFCLDSAKQTRQKVAVNWTNFSLKKTTPSTAQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96PV7-1", "uniprot_id": "F193B_HUMAN", "id": "Q96PV7-1", "name": "Protein FAM193B", "aln": "MTRRRSRPSGGAGRRERARAAGPQKPQAPEP-PPPPSLEAGAGAGPPEAPAEPDHDGPREDDEPNLVPGPQVPPASSQPVQTCCLLCHRERKGWEEGPSQNGLVLQGEKLPP-------------------DFMPKLVKNLLGEMPLWVCQSCRKSMEEDERQTGREHAVAISLSHTS-CKSQSCGD--------DSHSSSSSSS--------SSSSSSSSSCPGNSGDWDPSSFLS---------------AHKLSGLWNSPHSSGAMPGSSLGSP-----------------------PTIPGEAFPVSEHHQHSDLTAPPNSPTGHHPQPASLIPS--------HPSSFGS--PPHPHLLPTTPAAPFPAQASECPVAAATAPHTPGPCQSSHLPSTSMPLLKMPPPFSGCSHPCSGHCGGHCSGPLLPPPSSQPLPSTH-RDPGCKGHKFAHSGLACQLPQPCEADEGLGEEEDSSSERSSCTSSSTHQRDGKFCDCCYCEFFGHNAPPAAPTSRNYTEIREKLRSRLTRRKEELPMKGGTLGGIPGEPAVDHRDVDELLEFINSTEPKVPNSARAAKRARHKLKKKEKEKAQLAAEALKQANRVSGS-------REPRPARERLLEWPDRELDRVNSFLSSRLQEIKNTVKDSIRASFSVCELSMDSNGFSKEGAAEPEPQSLPPSNLSGSSEQQPDINLDLSPLTLGSPQNHTLQAPGEPAPPWAEMRGPHPP-WTEVRGPPPGIVPENGLVRRLNTVPNLSRVIWVKTPKPGYPSSEEPSSKEVPSCKQELPEPVS-SGGKPQKGKRQGSQAKKSEASPAPRPPASLEVPSAKGQVAGPKQPGRVLELPKVGSCAEAGEGSRGSRPGPGWAGSPKTEKEKGSSWRNWPGEAKARPQEQESVQPSGPARPQSLPQGKGRSRRSRNKQEKPASSLDDVFLPKDMDGVEMDETDREVEYFKRFCLDSAKQTRQKVAVNWTNFSLKKTTPSTAQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4ICN6-1", "uniprot_id": "A0A0R4ICN6_DANRE", "id": "A0A0R4ICN6-1", "name": "", "aln": "MARKKSKQQG-TGAKD---SVSVQQQQSLSKKPGDAVAGAAATGG-----------------------GDAGAARTSQSMHTCCLLCHREFKDWGSG-GANGLPAHGSRLAEAVPALSQALLRDAPGRTLADAVPSLSQSLLGEVPLWICQSCRRSVEEEERRTLQEQNSQVPLSHSSSCKSQSCGNGYPENSSVDWDPSSFLSARKLSGLWNSAHSNGGSHCNHNPAALSPGGTLGPACHEKRPSHDAPGKAAKTFGTKVCPYSHPASQNSSAASPGTLSASSDACKTNPKHFKTMCRRPTPPGEAFHPNDHHQSADLSVPPNSPTGLSSQHSSLLPPKQNSSQHVHVGSANSGLPSHAPFSPLVPNIHAPTAKHSSGPDSPVALHKPSACKNAHIPAVNSQHGKLSNSLIGCSHPCNGHSNGSS----VASPNAGHVTPGACRDQACKGHKVPNGSLCHTSP--CELEE--GDDEDSSSERSSCASSSNNQKDGKYCDCCYCEFFGHNAPPAAPTSRNYAEIREKLRSRLTRRKEELPQRQDLDPAAP--SAIDHRDVDELLDFINSTEPKPVNSAKAAKRARHKQKKKEKERALQCSMDAVGSDPRSASPPDPMEDSAPDADANRLLEWPQLELERVNSFLTSRLEEIKNTIKDSIRASFSMYDLNLDVNDFPKKAATLEG--NHLLSHLNGSSDLQ-QIDLDLAPLSLRN-----FKRDLDIVNGWEDTT-------TAAKD-----------IQRLHSTPSLSKLIRVRSPE-RIPAPESTQSAAKP--GEALPEIKSLAGAKMKKSKKQQEVSGKS----STHKAQEIKAADCDKSTKGGCKTQQVDAQKNGNKKAEEVKVCKQTSSNGHHNTATNTQQRAKNELSDTRGSRPEHDGDTKSISNTPSAQQ---PKGKTKNK-NKNKTEKSSNAIDDVFLPKDVDPTEMDEIDREVEYFKRFCLDSAKQTRQKVAVNWSNFSLKKMPSNAAQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*::*: .* :* :: :.. *: *: . * . *.* .* * .. :**.::********* *.* .* . *** :*.:*. * :*.* :.****:***:*****:*:**:**:* :: :.***:* *******. * ..** *: *: *...* * *.. .*.. *. * * * .*:* * .** .** *: **** .:*** :**:.******* .: :**:*. * .* .* ..:. * .* *: .. :..* * ...*:..* *:.. *:. .: ******.**..* . :..*.: :.. ** .*****..:..*. * :* *::**********:***.: :***:************** ********:****************** : . . * .*:*********:******** ***:******** ******:* .: : *.* * . :******: **:******:***:***.*:***: **:*: :*.:: ..* *:.:. . *.*.***: : :*:***:**:* . :: : . * : * .:. ::**::.*.**::* *::*: *:.*. .* * : *.* : :*.* :*.*:* . : *: :. . .::..... .. . :. : : .. ** : . : .. :.:*:: .. : * : : :* . . .*: .:** :.: .:** **.:.::********:* .**** **************************:****** ...:**", "identical_positions": 356, "similar_positions": 264, "identity": "35.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111102-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A4D2B0-1", "uniprot_id": "MBLC1_HUMAN", "id": "A4D2B0-1", "name": "Metallo-beta-lactamase domain-containing protein 1", "aln": "----MRTEPLCGASPLLVPGDPYSVVVLLQGYAEPEGVGDAVRADGSVTLVLPQTRGPASSHRESPRGSGGAEAALEEAARGPILVDTGGPWAREALLGALAGQGVAPGDVTLVVGTHGHSDHIGNLGLFPGAALLVSHDFCLPGGRYLPHGLGEGQPLRLGPGLEVWATPGHGGQRDVSVVVAGTALGTVVVAGDVFERDGDEDSWQALSEDPAAQERSRKRVLVVADVVVPGHGPPFRVLREASQPETEGGGNSQQEPVVGDEEPALH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BWY4-1", "uniprot_id": "MBLC1_MOUSE", "id": "Q8BWY4-1", "name": "Metallo-beta-lactamase domain-containing protein 1", "aln": "MNGPVRTEPLHGEIPLLASSGSYSVVVLLRGYAEPQGAGDAVRADGTVTLVLPRGWASDSSRGLAPSADGGSKTALEEAVRGPILVDTGGPWARGALLEALATQGVAPEDVTLVVGTHGHSDHIGNLGLFPEAALLVSHDFCLPEGLYLPHGLCETQPLILGSGLQVWATPGHGGQRDVSVVVEGTSLGTVVVAGDVFERLGDEDSWQALSEDPVAQQRSRERILSVADVVVPGHGAPFRVVRETVK--------SSEDLICEGKAVA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB40EC03-1", "uniprot_id": "A0AB40EC03_DANRE", "id": "A0AB40EC03-1", "name": "Metallo-beta-lactamase domain-containing protein 1", "aln": "MATHCSIRKTESGINSDICGQPYSVSVLKEGYCTAEDDG-AFRADGTITLIT------------GPN---------------TILVDTGGPWDRDFLVAKLKEKGLTPDSVDIVVGTHGHSDHVGNLGLFPEAKIIVGSDISVR-DKYLPNQLAEGQPYTIDDFVSIIFTPGHMG-RDVSVLVKGTSEGSVLVAGDLFERCHDEDSWKELSENPQIQEANRQMALQMADVIIPGHGPLFRVQRE--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . .*** ** .**. .:. * *.****::**: .* .********* * *: * :*::* .* :**********:******* * ::*. *:.: . ***: * * ** :. :.: **** * *****:* **: *:*:****:*** *****: ***:* *: .*: * :***::****. *** ** ", "identical_positions": 104, "similar_positions": 49, "identity": "38.52%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111102-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KAX2-1", "uniprot_id": "A0A0G2KAX2_RAT", "id": "A0A0G2KAX2-1", "name": "", "aln": "----MESQCDYSMYFPAVPLPPRAELAGDPGRYRALPRRNHLYLGETVRFLLVLRCRGSAGPGVG-GGTGLASRGAWTELATALAALASVSAGGVLP-------GCGSAGD-------QDADPPGGGDPGGGG----LFRSCSPLLTHG-PGPAT---SGGATTLPMEEPIVSTDEVIFPLTVSLDRLPPGTPKAKIVVTVWKREVEAPEVRDQGYLRLLQTRSPGETFRGEQSAFKAQVSTLLTLLPPPVLKCRQFTVAGKHLTVLKVLNSSSQEEISIWDIRILPNFNASYLPVMPDGSVLLVDNVCHQSGEVSMGSFCRLPGTSGYFPCPLSALEEHNFLFQLRGGEQPPPGAKEGLEVPLIAVVQWSTPKLPFTQSIYTHYRLPSVRLDRPCFVMTASCESPVRTYERFTVTYTLLNNLQDFLAVRLVWTPEHAQAGKQLCEEERRAMQAALDSIVCHTPLNNLGFSRKGSALTFSVAFQALRTGLFELSQHMKLKLQFTASVSHPPPEARPLSRKSSPSSPAVRDLVERHQA--SLGRSQSFSHQQPSRSHLMRSGSVMERRAITPPVASPVGRPLYLPPDKAVLSLDKIAKRECKVLVVEPVK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UTZ3-1", "uniprot_id": "TPC14_MOUSE", "id": "Q3UTZ3-1", "name": "Trafficking protein particle complex subunit 14", "aln": "----MESQCDYSMYFPAVPLPPRAELAGDPGRYRALPRRNHLYLGETVRFLLVLRCRGSVGAGVG-GGAGLASRGAWTELATSLAALASVSAGGALP-------GCGSAGD-------QDADPPGGGDPGGGG----LFRGCSPLLTHG-QGPAT---SGGATTLPVEEPIVSTDEVIFPLTVSLDRLPPGTPKAKIVVTVWKREVEAPEVRDQGYLRLLQTRSPGETFRGEQSAFKAQVSTLLTLLPPPVLKCRQFTVAGKHLTVLKVLNSSSQEEISIWDIRILPNFNASYLPVMPDGSVLLVDNVCHQSGEVSMGSFCRLPGTSGYFPCPLSALEEHNFLFQLRGGEQPPPGAKEGLEVPLIAVVQWSTPKLPFTQSIYTHYRLPSVRLDRPCFVMTASCESPVRTYERFTVTYTLLNNLQDFLAVRLVWTPEHAQAGKQLCEEERRAMQAALDSIVCHTPLNNLGFSRKGSALTFSVAFQALRTGLFELSQHMKLKLQFTASVSHPPPEARPLSRKSSPSSPAVRDLVERHQA--SLGRSQSFSHQQPSRSHLMRSGSVMERRAITPPVASPVGRPLYLPPDKAVLSLDKIAKRECKVLVVEPVK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WVR3-1", "uniprot_id": "TPC14_HUMAN", "id": "Q8WVR3-1", "name": "Trafficking protein particle complex subunit 14", "aln": "----MESQCDYSMYFPAVPLPPRAELAGDPGRYRALPRRNHLYLGETVRFLLVLRCRGGAGSGTG-GGPGLGSRGAWAELATALAALASVSAGGGMP-------GGGGAGD-------QDSEPPGGGDPGGGG----LFRGCSPLLTHG-PGPAT---SGGATTLPVEEPIVSTDEVIFPLTVSLDRLPPGTPKAKIVVTVWKREIEAPEVRDQGYLRLLQTRSPGETFRGEQSAFKAQVSTLLTLLPPPVLRCRQFTVAGKHLTVLKVLNSSSQEEISIWDIRILPNFNASYLPVMPDGSVLLVDNVCHQSGEVSMGSFCRLPGTSGCFPCPLNALEEHNFLFQLRGGEQPPPGAKEGLEVPLIAVVQWSTPKLPFTQSIYTHYRLPSVRLDRPCFVMTASCKSPVRTYERFTVTYTLLNNLQDFLAVRLVWTPEHAQAGKQLCEEERRAMQAALDSVVCHTPLNNLGFSRKGSALTFSVAFQALRTGLFELSQHMKLKLQFTASVSHPPPEARPLSRKSSPSSPAVRDLVERHQA--SLGRSQSFSHQQPSRSHLMRSGSVMERRAITPPVASPVGRPLYLPPDKAVLSLDKIAKRECKVLVVEPVK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F240-1", "uniprot_id": "TPC14_DANRE", "id": "E7F240-1", "name": "Trafficking protein particle complex subunit 14", "aln": "MVLMMESQCEYFMYFPAVPIS---DLS-DPAKYRTLPRRSHLYLGETVRFLLVLRSQSASGSSDGSCGSEQHSSRSWRELAGSLSAVASVSPGDSRQRTQPLYHDYHSSGDECVEDTDEDDAAEAVGCPGRGGPRYRGFRECKPLLIHNNPGNGVREFRRAPVQSPVDEPVVLSDEVIFPLTVSLDKLPVNTLKVKIIVTVWKQEEEKAEIQEHGYLSILQQKSPCQTFRQDLNTFKAQVSTTLNVLPPPTVKCQQMTVSGRHLTVLKVLNGSSQEEVCVRDVKILPNFNASYLPMMPDGSVLLVDNVCHQSGEVAMASFYRMDSESSHLPSMLSALEEQNFLFQLQLNNQPQDDSNEGLEVPLVAVLQWSTSKLPFTNSIYTHYSLPSIRLDRPRFIMTASCPSAVRTRENFRVRYTLLNNLQDFLAVRLVWTPE----GRGQKED------PAVNAVVCHSPLSNLGYCRKGSTLSVSVAFQILRAGLFELSQHMKLKLQFTASVSNPPPDARPLSRKNSPSSPAVRDILDRHQASLSLGRSQSFSHQQPSKFHLTRTGSVMERRAITPPVGSPVGRPLYLPPDRNILSLDKIAKRECKVLVLDSHN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****:* *******:. :*: **.:**:****.***************.:.. *.. * *. * :* *** :*:*:****.*. . .:** :* . . * ** ** ** *.*** *. * .. ... *::**:* :************:** .* *.**:*****:* * .*::::*** :** :** :*** : .:******* *.:****.::*:*:**:*:*********.*****:.: *::***********:*******************:*.** *: . *. :*. *.****:******: .:** .::*******:**:****.*****:****** ***:***** *:***** *.*** *.* * ******************** *: *: .*::::***:**.***:.****:*:.***** **:********************:***:*******.*********:::**** **************: ** *:*************.************: :***************::. :", "identical_positions": 377, "similar_positions": 124, "identity": "61.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111103-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6NL82-1", "uniprot_id": "CF144_HUMAN", "id": "A6NL82-1", "name": "Cilia- and flagella-associated protein 144", "aln": "MAGHPKEKVIPDEVHQNQILRELYLKELRTQKLYTQYHVNPLRKIHTVTRKPMSWHDNLEEPADARFLNLIHHAAQGPRKKYPETQTENQEVGWDLEPLINPERHDRRLNHFRVCSDITLYKAKTWGLGDDHHK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FBI9-1", "uniprot_id": "E7FBI9_DANRE", "id": "E7FBI9-1", "name": "", "aln": "MA-KLKEKEPLDIVHQNAIHVETIMKELRHQKLYTEFNINPFKKLHVLTDKPMSSIAHKKEEGDPAFLQAVHNAHLEPTKKYTHPQTESQEIGWLSSPLLVTDRSDRRLNFPRQNSEITKYMDAAWRLKEQTQNMR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** : *** * **** * * :**** *****::::**::*:*.:* **** : :* .*. **: :*:* * ***...***.**:** .**: .:* *****. * *:** * :* * :: :: ", "identical_positions": 62, "similar_positions": 34, "identity": "45.59%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111103-33", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9EPW4-1", "uniprot_id": "CLC3A_MOUSE", "id": "Q9EPW4-1", "name": "C-type lectin domain family 3 member A", "aln": "MAKNGLVLCILVVSLLLDQTDGYPSRMKARKHSKRRVKAKDDDLKSQVEKLWREVNALKEMQALQTVCLRGTKVHKKCYLASEGLKHYHEANEDCISKGGTLVVPRNSDEINALRDYGKRSLPGVNDFWLGINDMVTEGKFLDVHGFAVSFLNWDRAQ--PSGGKRENCVLFSQSAQGKWSDEACRSSKRYICEFIIP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75596-1", "uniprot_id": "CLC3A_HUMAN", "id": "O75596-1", "name": "C-type lectin domain family 3 member A", "aln": "MAKNGLVICILVITLLLDQTTSHTSRLKARKHSKRRVRDKDGDLKTQIEKLWTEVNALKEIQALQTVCLRGTKVHKKCYLASEGLKHFHEANEDCISKGGILVIPRNSDEINALQDYGKRSLPGVNDFWLGINDMVTEGKFVDVNGIAISFLNWDRAQ--PNGGKRENCVLFSQSAQGKWSDEACRSSKRYICEFTIPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8Q4Q2-1", "uniprot_id": "A0A2R8Q4Q2_DANRE", "id": "A0A2R8Q4Q2-1", "name": "", "aln": "MRQFLLLLLVFCFSFIQDG-YGHPSRTKKAVPARQRE---EDDMKTQIDKLWQEVNSLKEMQALQTVCLRGIKAHRKCYLVSDQAKHYHEANEDCISQGGTLAIPRDVNENEELRDYAKRSSPAARDFWIGITDIVREGQYVDVNSLPVSFFYWDRAKKEPTGGKRESCVALSLSAQGKWHDEVCRSQKKYICEYLIP-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : *:: :: .::: * .:.** * :::* :.*:*:*::*** ***:***:********** *.*:****.*: **:*********:** *.:**: :* : *:**.*** *...***:**.*:* **:::**:.:.:**: ****: *.*****.** :* ****** **.***.*:****: ** ", "identical_positions": 104, "similar_positions": 59, "identity": "52.26%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111104-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O15442-1", "uniprot_id": "MPPD1_HUMAN", "id": "O15442-1", "name": "Metallophosphoesterase domain-containing protein 1", "aln": "MWRSRWDASVLKAEALALLPCGLGMAFSQSHVMAARRHQH-----SRLIIEVDEYSSNPTQAFTFYNINQGRFQPPHVQMVDPVPHDAPKPPGYTRFVCVSDTHSRTDPIQMPYGDVLIHAGDFTELGLPSEVKKFNEWLGSLPYEYKIVIAGNHELTFDQEFMADLIKQDFYYFPSVSKLKPENYENVQSLLTNCIYLQDSEVTVRGFRIYGSPWQPWFYGWGFNLPRGQALLEKWNLIPEGVDILITHGPPLGFLDWVPKKMQRVGCVELLNTVQRRVQPRLHVFGHIHEGYGVMADGTTTYVNASVCTVNYQPVNPPIVIDLPTPRNS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q91ZG2-1", "uniprot_id": "MPPD1_MOUSE", "id": "Q91ZG2-1", "name": "Metallophosphoesterase domain-containing protein 1", "aln": "MWRPRWDPGILKAEALALLPCGLGMAFSQSHVMASRRHQH-----GRLIIEVDEYSSNPTQAFTFYNINQGRFQPPHVQMVDPVPHDAPKPPGYTRFVCVSDTHSRTDPIQMPYGDVLIHAGDFTELGLPSEVKKFNEWLGSLPYEYKIVIAGNHELTFDQEFMADLIKQDFYYFPSVSKLKPENYENVQSLLTNCIYLQDSEVTVRGFRIYGSPWQPWFYGWGFNLPRGQALLEKWNLIPEGVDILITHGPPLGFLDWVPKKMQRVGCVELLNTVQRRVQPRLHVFGHIHEGYGVMADGTTTYVNASVCTVNYQPVNPPIVIDLPTPRNS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QUV1-1", "uniprot_id": "F1QUV1_DANRE", "id": "F1QUV1-1", "name": "", "aln": "------------------------MAFTLSEIMAARRQQQQSQRGGRGVVEVDEYSANPTQAFTFYNINQGRFQPPHVHMVDPIAHDTPKPPGYTRFVCISDTHSRTDAIQMPYGDVLLHAGDFTELGLPSEVKKFNDWLGTLPYEIKIVIAGNHELTFDQEFMADLIKQDFYYFPSASKLKPENYENVQSLLTNCIYLQDSDVTVRGFRIYGSPWQPWYYGWGFNLPRGQALLDKWNQIPDSTDILLTHCPPLGFLDWVPRKMQRVGCMELLNTVQRRVQPKLHVFGHIHEGYGVMTDGTTTFVNASACTVNFQPMNPPIVFDLPNPRSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***: *.:**:**:*: .* ::******:*********************:****:.**:***********:********.*********:******************:***:**** ******************************.************************:****************:**************:*** **:..***:** **********:*******:************:**************:*****:****.****:**:*****:***.**.*", "identical_positions": 259, "similar_positions": 38, "identity": "78.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111104-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LNQ2-1", "uniprot_id": "F1LNQ2_RAT", "id": "F1LNQ2-1", "name": "Activating molecule in BECN1-regulated autophagy protein 1", "aln": "MKVVPEKNAVRILWGRERGTRAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLLHNFLHMLSSRSSGIQVG-EQSTVQDSATPSPPPPPPQPSTERPRTSAYIRLRQRVSYPTTVECCQHPGILCLCSRCAGTRVPSLLPHQDSVPPASARATTPSFSFVQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHRELAPGLTGSEWTR----TVLTLNSRSEVESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPSSGLATESDGGNGSSQNNSGNIRHELQCDLRRFFLEYDRLQELDQSLSGETPQTQQAQEMLNNNIESERPGPSHQPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASSSWHVS-TTFEGMPPSGN------QLPPLERTEGQMPNSSRLELSSSASSQEERTVGVAFNQETGHWERIYTQ--SSRSGTVSQEALHQDMPEESSEEDSLRRRLLESSLISLSRYDGAGSREHPIYPDPARLSPAAYYAQRMIQYLSRRDSIRQRSMR-YQQNRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVP-RRFLLPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETSMRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGIEYYWDQLNETVFTVH-------SSSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPTTSVTSQGTQTLALQLQNAETQTEREEEE----PGTAS-------------------------------SGPGEGEGSEYGGSGED------ALSRIQRLMAEGGMTAVVQREQSTTMASMGGFGNNIIVSHRIHRSSQTGTESGAARTSSPQPSTSRGLLSEPGQLAERGLSPRTASWDQPSTSGRELP-QPALSSSSPVPIPVPLAS-NEGPTMHCNVTNNSHLPEGDSSNVGE-------AAGPSGEPRNR-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AH22-1", "uniprot_id": "AMRA1_MOUSE", "id": "A2AH22-1", "name": "Activating molecule in BECN1-regulated autophagy protein 1", "aln": "MKVVPEKNAVRILWGRERGTRAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLLHNFLHMLSSRSSGIQVG-EQSTVQDSATPSPPPPPPQPSTERPRTSAYIRLRQRVSYPTTVECCQHPGILCLCSRCAGTRVPSLLPHQDSVPPASARATTPSFSFVQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHRELAPGLTGSEWTR----TVLTLNSRSEVESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPSSGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEYDRLQELDQSLSGETPQTQQAQEMLNNNIESERPGPSHLPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASSSWHVS-TTFEGMPPSGN------QLPPLERTEGQMPSSSRLELSSSASSQEERTVGVAFNQETGHWERIYTQ--SSRSGTVSQEALHQDMPEESSEEDSLRRRLLESSLISLSRYDGAGSREHPIYPDPARLSPAAYYAQRMIQYLSRRDSIRQRSMR-YQQNRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVP-RRFLLPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETSMRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGIEYYWDQLSETVFTVH-------SSSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPTTSVTSQGTQTLALQLQNAETQTEREEEE----PGAAS-------------------------------SGPGEGEGSEYGGSGED------ALSRIQRLMAEGGMTAVVQREQSTTMASMGGFGNNIIVSHRIHRSSQTGTESGAARTSSPQPSTSRGLPSEPGQLAERALSPRTASWDQPSTSGRELP-QPALSSSSPVPIPVPLAS-NEGPTMHCNVTNNSHLPEGDGSNRGE-------AAGPSGEPQNR-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0C7-1", "uniprot_id": "AMRA1_HUMAN", "id": "Q9C0C7-1", "name": "Activating molecule in BECN1-regulated autophagy protein 1", "aln": "MKVVPEKNAVRILWGRERGARAMGAQRLLQELVEDKTRWMKWEGKRVELPDSPRSTFLLAFSPDRTLLASTHVNHNIYITEVKTGKCVHSLIGHRRTPWCVTFHPTISGLIASGCLDGEVRIWDLHGGSESWFTDSNNAIASLAFHPTAQLLLIATANEIHFWDWSRREPFAVVKTASEMERVRLVRFDPLGHYLLTAIVNPSNQQGDDEPEIPIDGTELSHYRQRALLQSQPVRRTPLLHNFLHMLSSRSSGIQVG-EQSTVQDSATPSPPPPPPQPSTERPRTSAYIRLRQRVSYP-TAECCQHLGILCLCSRCSGTRVPSLLPHQDSVPPASARATTPSFSFVQTEPFHPPEQASSTQQDQGLLNRPSAFSTVQSSTAGNTLRNLSLGPTRRSLGGPLSSHPSRYHREIAPGLTGSEWTR----TVLSLNSRSEAESMPPPRTSASSVSLLSVLRQQEGGSQASVYTSATEGRGFPASGLATESDGGNGSSQNNSGSIRHELQCDLRRFFLEYDRLQELDQSLSGEAPQTQQAQEMLNNNIESERPGPSHQPTPHSSENNSNLSRGHLNRCRACHNLLTFNNDTLRWERTTPNYSSGEASSSWQVP-SSFESVPSSGS------QLPPLERTEGQTPSSSRLELSSSASPQEERTVGVAFNQETGHWERIYTQ--SSRSGTVSQEALHQDMPEESSEEDSLRRRLLESSLISLSRYDGAGSREHPIYPDPARLSPAAYYAQRMIQYLSRRDSIRQRSMR-YQQNRLRSSTSSSSSDNQGPSVEGTDLEFEDFEDNGDRSRHRAPRNARMSAPSLGRFVP-RRFLLPEYLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVQNCKIYNDASCDISADGQLLAAFIPSSQRGFPDEGILAVYSLAPHNLGEMLYTKRFGPNAISVSLSPMGRYVMVGLASRRILLHPSTEHMVAQVFRLQQAHGGETSMRRVFNVLYPMPADQRRHVSINSARWLPEPGLGLAYGTNKGDLVICRPEALNSGVEYYWDQLNETVFTVH-------SNSRSSERPGTSRATWRTDRDMGLMNAIGLQPRNPATSVTSQGTQTLALQLQNAETQTEREVPE----PGTAA-------------------------------SGPGEGEGSEYGASGED------ALSRIQRLMAEGGMTAVVQREQSTTMASMGGFGNNIIVSHRIHRSSQTGTEPGAAHTSSPQPSTSRGLLPEAGQLAERGLSPRTASWDQPGTPGREPT-QPTLPSSSPVPIPVSLPS-AEGPTLHCELTNNNHLLDG-GSSRGD-------AAGPRGEPRNR-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FAG6-1", "uniprot_id": "AMR1A_DANRE", "id": "E7FAG6-1", "name": "Activating molecule in BECN1-regulated autophagy protein 1A", "aln": "MKLG-QRNSVCILSSRERGAPGLASYRVLQQLVEEKTQRMKWQSQKVELPDSPRSTFLLAFSPDRSLMASTHVNHNIYITEVKSGKCVHSLVGHRRTPWCLTFHPIIPGLIASGCLDGEVRIWDLHGGSESWLTESNSAIASLAFHPTAQLLLIATNNEVHLWDWSRKEPFTVVKTASETERVRLVRFDPLGHYLLTAIVNPSNQPNDDDPEIPMDSVEMPHLRQRSFLQSQPARRTPILHNFLHILTSRNSVPQAGGAHSASTDGSSDS-------------------------SGPYTLMCVQPLGMVCFCSRCSAARVPSP-PDEDPSDSASLEAQAHTFSSARTEPLQMSRFSVESR----AANRSSAFSSVYG--GGSNMRNHSSSSGRRGVTG---MAPVPHFRQHPPGREGGGRHPGADWTVSGLNGQS--SSMTPQRTGASSVSLLSVLRQQETSFQSPVYTSASDRWGSTPGTSSSRHRPPEEEGQSSSSSIHSVLRCNLYRYFMDYEGTQDTVQPLDGSR-QDQQTQEMLNNNMDPEQPGPSHYQSPYSGENPP---HSHMNRCRVCHNLFTYNQGSRRWDRTGQ-PSSTERNTPWQPSSSAFHSVAPVSQSNEHLLEHRPIESTPNTPEPHVPFSQRTDTGQHEEQAVGLVFNQETGQLERVYRQSASSRSANISQGALNQEMPEDTPDNDYLRR-----------------------------LSPAAYYAQRMIQYLSRRDSVRQHSHRPPSRPRPLSSNPSSLSPSPVPNAESSEVDFEEFEENG--SRYRTPRNARMSAPSLGRFVGTRRFLLPEFLPYAGIFHERGQPGLATHSSVNRVLAGAVIGDGQSAVASNIANTTYRLQWWDFTKFDLPEISNASVNVLVPNCKIYNDASCDISADGQLLAVFIPSSQRGFPDEGILAVYSLAPHNLGEMLYSKRFGPNAISVSLSPMGRYVMVGLASRRILLHQISDHMVAQVFRLQQPHAGETSMRRVFDVVYPMAPDQRRHVSINSARWLPDPGLGLAYGTNKGDLVICRPVDVHS-DGSSTSEHSERMFTINNGGGVGPSSSRSGDRAGSSRTDRRSRRDIGLMNGVGLQPQPPAASVTSQGTQTQNQRLQHAETQTDRDLPDDPQQPSTSQGSQVTDATESLDFETLPEDSGSEVVPETPPHSRPQEDEGSDPSEPSTDSTGQAEYVSRIRRLMAEGGMTAVVQREQSTTMASMGSFGNNIIVSHRIHRGSQTGADAQNRTRLSPIPGPSSGAPESLAAASYSRVLTNTLGFRGDTAQGIDLTEQERLHTSFFTPEFSPLFSSAVDATGPSSSIGADSVLEGEDFHDFASLPPSLLSSSPSLSPVNNSNYSNSDSSYLGDEYGR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: ::*:* ** .****: .:.: *:**:***:**: ***:.::*******************:*:***************:*******:********:**** *.************************:*:**.****************** **:*:*****:***:******* ************************* .**:****:*..*:.* ***::*****.****:******:*:**.* *.* :*: *.:: * * * * * * *::*:****:.:**** *.:*. .** .* : :** .:***:: .. : .:: **.****:* . .*..:** * .. **.: * * :.*: .** *. ** **.:* .**.* **.************** . *:.*****:: * ... ::. : ..*..*..*: *:*:* *:*::*: *: *.*.*. * **:*******::.*:***** :*:*.** . :.*:****.****:*:*:.: **:** ** * .:.*: . ::*..:.. .. : *:* * . :. :.:. :**::**:.******: **:* * ****..:** **:*:***::.::* *** ********************:**:* * .: * **..** * . *..*.::::**:**:** **:*:*************** *******:********************************************************************** ********************.******************************:******************************* ::***********.*.*********:*:***..***************:******************* ::* .: .* :**:: *.***.:*.*:**: *: **:****.:****: *::********* :**:*****:*: : *.:: * * *.***: . .. * :***:************************.*************.****::. ** *..* * . . : : ..* .: : * : . * * :* .* .* * ..* .. . . : :* . ::.* .* *. ", "identical_positions": 745, "similar_positions": 284, "identity": "53.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111104-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08560-1", "uniprot_id": "DGKZ_RAT", "id": "O08560-1", "name": "Diacylglycerol kinase zeta", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPRDPSPEARS--SDSESASASSSG-------SERDADPEPD-----------------------KAPRRLTK-----------------------------------------------------------------------------------------------------------RRFPGLRLFG---------------------------------------------------------------------------HRKAITKSGLQHLAP-------PPPTP---------------------------------------------GAPCGESERQIRSTVDWSESAAYGEHIWFETNVSGDFCYVGEQYCVAKMLPKSAPRRKCAACKIVVHTPCIGQLEK------------------------INFRCKPSFRESGSRNVREPTF--------------------------------VRHHWVHRRRQDGKCRHCGKGFQQKFTFHS-----KEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRP---QNTLKASKKKKRAS-----------------FKRRSSK--KGPEEGR-WRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPREALEMYRKVHNLRILACGGDGTVGWILSTLDQLR--LKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLRAEPNPEAGPEERDDGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCIVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVLLTTAKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSTAPLHSD-QQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQ---------------EPDGAGAKSPMCHPLSSKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLG---ASARPDLPTPTSP-----------LPASPCSP--TPG----------------------------------------------------------SLQGDAALPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDHQSRTLLHHAVSTGSKEVVRYLLDHAPPEILDAVE-ENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80UP3-1", "uniprot_id": "DGKZ_MOUSE", "id": "Q80UP3-1", "name": "Diacylglycerol kinase zeta", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPRDPSPEGRS--SDSESASASSSG-------SERDAGPEPD-----------------------KAPRRLTK-----------------------------------------------------------------------------------------------------------RRFPGLRLFG---------------------------------------------------------------------------HRKAITKSGLQHLAP-------PPPTP---------------------------------------------GAPCGESEEQIQSTVDWSESAVYGEHIWFETNVSGDFCYVGEQHCVAKMLPKSAPRKKCAACKIVVHTQCIKQLEK------------------------INFRCKPSFRESGSRNVREPTF--------------------------------VRHHWVHRRRQDGKCRHCGKGFQQKFTFHS-----KEIVAISCSWCKQAYHSKVSCFMMQQIEEPCSLGVHAAVVIPPTWILRARRP---QNTLKASKKKKRAS-----------------FKRRSSK--KGPEEGR-WRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPREALEMYRKVHNLRILACGGDGTVGWILSTLDQLR--LKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLRAEPNPEAGPEERDDGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCIVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVLLTTAKAIPVQVDGEPCKLSASRIRIALRNQATMVQKAKRRSTAPLHSD-QQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQR---------------EPDGAGAKSPMCHQLSSKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLG---ASARPDLPTPTSP-----------LPASPCSP--TPG----------------------------------------------------------SMQGDTALPQGEELIEAAKRNDCCKLQELHRAGGDLMHRDQKSRTLLHHAVSTGSKEVVRYLLDHAPPEILDAVE-ENGETCLHQAAALGQRTICHYIVEAGASLMKTDLQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13574-2", "uniprot_id": "DGKZ_HUMAN", "id": "Q13574-2", "name": "Diacylglycerol kinase zeta", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPRDGSPEARS--SDSESASASSSG-------SERDAGPEPD-----------------------KAPRRLNK-----------------------------------------------------------------------------------------------------------RRFPGLRLFG---------------------------------------------------------------------------HRKAITKSGLQHLAP-------PPPTP---------------------------------------------GAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGEQYCVARML-KSVSRRKCAACKIVVHTPCIEQLEK------------------------INFRCKPSFRESGSRNVREPTF--------------------------------VRHHWVHRRRQDGKCRHCGKGFQQKFTFHS-----KEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRP---QNTLKASKKKKRAS-----------------FKRKSSK--KGPEEGR-WRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLR--LKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSD-QQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQ---------------EPDGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLG---ASARPDLPTPTSP-----------LPTSPCSP--TPR----------------------------------------------------------SLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVE-ENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q2N7-1", "uniprot_id": "A0A8M9Q2N7_DANRE", "id": "A0A8M9Q2N7-1", "name": "Diacylglycerol kinase", "aln": "--------------------------------------------------------------------------------------MDALFNLRFRRKAVEPSGRRRSSVSLPASKARRRSSAGLPSAGLAHRRRSSAQLQIGSIQPG------LVLHRRGHFTRRKSSGGT----------ACLTPRFAIRRRQAAKHRSIHAQLLGPSLLLAS-----VVQMSEDHEPEDKSAEEYSSLSDTDCSQDEHEQ-------TGMDFETESDKCLTWLAQG-LLVGESIQPRPLIRAPRCLRRNSSHLLPAEAVYR-----------------------------------------------------------------------------------SPASYGLYGRYRRTSQVHNMGGLWAGKRSSLAARGSVALYRTSPPCWPDLSVSHTLQGTYYNPQIDTWSG-------------------------FLSKAIAKSGLQHLSC-------QPSAA---------------------------------------------VLAKGETDREIRNTVDWSESAVYGEHIWFETNVSGDFCYVGEQHCYAKSLQKSVARKKCAACKIVVHSICIEQLEKLLDWNAPPQGEGLDEMPLKEPSFRINFRCKPSFRESGSRNIREQTWRRRAFRGRCALEQMRGAAAKCTAHTSNTQPAIVRHHWVHRRRQEGKCKQCGKGFQQKFAFHS-----KEIVAISCSWCKQAYHNKVTCFMLQQIEEPCSLGAHAAVIVPPTWIIRVRRP---QSSLKSSKKKKRTS-----------------FKRKSSK--KGAEEAR-WKPFIVRPIPSQLMKPLLVFVNPKSGGNQGAKIIQTFLWYLNPRQVFDLSQGGPQEGLEMYRKVHNLRILACGGDGTVGWILSALDQLQ--LNPSPAVAVLPLGTGNDLARTLNWGGGYTDEPLSKILSHVEDGNIVQLDRWNLVVKPNPEAGPEERDEQVTDKLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIKVVCDGTDLTSKVQDLKLQCLVFLNIPRYCAGTMPWGNPSEHHDFEPQRHDDGCIEVIGFTMTSLATLQVGGHGERLNQCREVTLTTFKSIPMQVDGEPCKLAPSVIHISLRNQANMVQKTKRRTSIPLLNDSQQPFPERLRIRVSRISMHDYEALHYDKEKLKEASIPLGLIVVPGDSDLETCRAHIERLQEDFVSCNPSLQRLVLQEGDGSKSKALSSQRLSPKWCFLDSTTADRFYRIDRAQEHLNYVTEISQDELFVLDPELVVTETVSTSPGMPDLVDSGEVQSDPHKFAFPSSSSSPPNTPGPRVAELQRKRVSSDSSVAEALAHSDSLRSAKPALCRAGGVHRSNTTAADFKPTSRFEKSAVNNANSVSVDSLIECVKKKDHQKLKELHKKGADLCVQDPAGRTLLHYAVEVGSKEIVKYIIDNAPTDILDVTEKENGETVLHKAASLCHRTICHYLVEAGASLMKTDLQGDTPKHRAEKAKDAELAAYLENRQHYQMIQREDQETAV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q09103-1", "uniprot_id": "DGK2_DROME", "id": "Q09103-1", "name": "Eye-specific diacylglycerol kinase", "aln": "MQQQQQPSIDQLPEPTASTSNSATTKPTIATATTSTTTTSGNNFHQQLQATTAATMQRLRTTFTRSRTPTGAEMKMQNSLEVPKQVRSASFDEMQLESQRASSSLLKQQSSSSASADERSSEAGFLQVPLAAHQQRSHSFDSATASAGSDDSGTFLEVPRRLKARRSSSTKTPPPCIHCHYLEEYERRMTAEQRYFIDHRELTALSYSNTSSEASEDEDEVEGHNAEEEEEGSAAIEDAEEETTEAATEEADEDPRTEVESEHDHDPDDDAALEMDIRIGNMSQGSSIEESRARLPRQMRRHTIGSSSVTSASEDEGLEGSDNGSPHFGNTLLPPQPTTPCGITFTLSPTNGDYPSPPHLPLDPGSPPISPCSSNSGRLPALAPIISTPCSSADADDAGAAMGLPVRARRRSISRQEAIFVEPTGNSLENVSHEEVDNSNTKSSVDTADSLDEASTMATCGSPGAAGGSGASSSHHNAFVVRDIYLMVPDLKRDRAASVDSCFSKLSSNAKTEELQPSADGCFLTVPNINATRSRSVDIVLPTDEQARYKALSMTGSTVTYADGRTASASNSRRPIRIVPDWTENAVQGEHYWKPTSASGDLC------CLNEECIKSGQRMKCSACQLVAHHNCIPFVNE-----------------------KSTLACKPTYRDVGIRQYREQTT--------------------------------THHHWVHRKLEKGKCKQCGKFFPMKQAVQSKLFGSKEIVALACAWCHEIYHNKEACFNQAKIGEECRLGNYAPIIVPPSWIVKLPTKGNFKSSIRVSNKNNAASGSGGGGAGGGAGGGGGKSKKQTQRRQKGKEEKKEPRAFIVKPIPSPEVIPVIVFINPKSGGNQGHKLLGKFQHLLNPRQVFDLTQGGPKMGLDMFRKAPNLRVLACGGDGTVGWVLSVLDQIQPPLQPAPAVGVLPLGTGNDLARALGWGGGYTDEPIGKILREIGMSQCVLMDRWRVKVTPNDDVTDDHVD-RSKPNVPLNVINNYFSFGVDAHIALEFHEAREAHPERFNSRLRNKMYYGQMGGKDLILRQYRNLSQWVTLECDGQDFTGKLRDAGCHAVLFLNIPSYGGGTHPWN---DSFGASKPSIDDGLMEVVGLTTYQLPMLQAGMHGTCICQCRKARIITKRTIPMQVDGEACRVKPSVIEIELLNKALMLSKRKHG-----RGDVQVNPLEKMQLHILRVTMQQYEQYHYDKEMLRKLANKLGQIEIESQCDLEHVRNMLNTKFE----------------------ESISYPKVSQDWCFIDSCTAEHYFRIDRAQEHLHYICDIAIDELYILDHEAAT---MPQTPDQERSFAAFSQRQAQNE--RRQMDQAQGRGPGSTDEDLQIG------------------------------------------SKPIKVMKWKSPILEQTSDAILLAAQSGDLNMLRALHEQGYSLQSVNKNGQTALHFACKYNHRDIVKYIIASATRRLINMADKELGQTALHIAAEQNRRDICVMLVAAGAHLDTLDSGGNTPMMVAFNKNANEIATYLESKQGTQPVDGWLDD---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .. :. : . ::.: . . : * .: * : ** : : ** . : . * ..* :.:*: *.: . .:: . *: . **:*.*. *** * *..***:* * . ** * **:**::*.* ** ::: .: ***::*: * *: ** * .:******: :.***::*** * * :.:* *****::*:**:: **.* :** :* * * ** :*.:::**:**:: :.::: *:*:: :* *:::.: ** ** : :.**::* ** : *::**:********* *:: .* *********:****: .*:*:**. ***:***********:**.***:: *:*.*.*.:***********:*.*********:.*** .: .: * :*** : . ** :. :. * . .:**:*:*****:*.***::*****:***:**:****:****:*. . .*::: . ::*:: : : *** *:* *::* :.::***** * .** **. : .. . *** :**:*:* .*. **.* ** : ***:. : * ::**:*****.*:: .* *.* * *:* *:.* *: .* * *:::::: *::*::** ***** *:: : ** : : .:.*** * :: . :: :* .***:*: **.:::*********:*: :*: **:::** * . *. . : * . . : :: ..: * *: **. * .* : .:* **.* . . :::*:*:: *. ::: .: * *:* ** ** :* ** :* *** * . * *:** * : : *:*:***.:* * :: :: ", "identical_positions": 350, "similar_positions": 288, "identity": "21.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111104-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O08560-1", "uniprot_id": "DGKZ_RAT", "id": "O08560-1", "name": "Diacylglycerol kinase zeta", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPRDPSPEARS-------------------------SDSES-----------------------------ASASSSGSER------------------------------------------------------------------DADPE-PDKAPRRLTKRR--------------------FPG--LRLFGHR----------------------------------------------------------------------------------------------KAITKSGLQHLAPPPP-------------------------------------------TPGAPCGESERQIRSTVDWSESAAYGEHIWFETNVSGDFCYVGEQYCVAKMLPKSAPRRKCAACKIVVHTPCIGQL-EKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHS-----KEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRP---QNTLKASKKKKRAS--------------------FKRRSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPREALEMYRKVHNLRILACGGDGTVGWILSTLDQLR--LKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLRAEPNPEAGPEERDDGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCIVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVLLTTAKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSTAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPMCHPLSSKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLG---ASARPDLP-------------TPTSPLPASPCSPTPG----------------------------------------------------------SLQGDAALPQG-------------------EE----------------------LIEAAKRNDFCKLQELHRAGGDLMHRDHQSRTLLHHAVSTGSKEVVRYLLDHAPPEILDAVEE-NGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80UP3-1", "uniprot_id": "DGKZ_MOUSE", "id": "Q80UP3-1", "name": "Diacylglycerol kinase zeta", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPRDPSPEGRS-------------------------SDSES-----------------------------ASASSSGSER------------------------------------------------------------------DAGPE-PDKAPRRLTKRR--------------------FPG--LRLFGHR----------------------------------------------------------------------------------------------KAITKSGLQHLAPPPP-------------------------------------------TPGAPCGESEEQIQSTVDWSESAVYGEHIWFETNVSGDFCYVGEQHCVAKMLPKSAPRKKCAACKIVVHTQCIKQL-EKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHS-----KEIVAISCSWCKQAYHSKVSCFMMQQIEEPCSLGVHAAVVIPPTWILRARRP---QNTLKASKKKKRAS--------------------FKRRSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPREALEMYRKVHNLRILACGGDGTVGWILSTLDQLR--LKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLRAEPNPEAGPEERDDGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCIVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVLLTTAKAIPVQVDGEPCKLSASRIRIALRNQATMVQKAKRRSTAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQREPDGAGAKSPMCHQLSSKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLG---ASARPDLP-------------TPTSPLPASPCSPTPG----------------------------------------------------------SMQGDTALPQG-------------------EE----------------------LIEAAKRNDCCKLQELHRAGGDLMHRDQKSRTLLHHAVSTGSKEVVRYLLDHAPPEILDAVEE-NGETCLHQAAALGQRTICHYIVEAGASLMKTDLQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13574-2", "uniprot_id": "DGKZ_HUMAN", "id": "Q13574-2", "name": "Diacylglycerol kinase zeta", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEPRDGSPEARS-------------------------SDSES-----------------------------ASASSSGSER------------------------------------------------------------------DAGPE-PDKAPRRLNKRR--------------------FPG--LRLFGHR----------------------------------------------------------------------------------------------KAITKSGLQHLAPPPP-------------------------------------------TPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGEQYCVARML-KSVSRRKCAACKIVVHTPCIEQL-EKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQDGKCRHCGKGFQQKFTFHS-----KEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVIPPTWILRARRP---QNTLKASKKKKRAS--------------------FKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFVNPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWILSTLDQLR--LKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWDLHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPWGHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSKAIPVQVDGEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALHYDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLDATTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLG---ASARPDLP-------------TPTSPLPTSPCSPTPR----------------------------------------------------------SLQGDAAPPQG-------------------EE----------------------LIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVRYLLDHAPPEILDAVEE-NGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEKAQDTELAAYLENRQHYQMIQREDQETAV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RN59-1", "uniprot_id": "A0A8M1RN59_DANRE", "id": "A0A8M1RN59-1", "name": "Diacylglycerol kinase", "aln": "------------------------------------------------------MDTFFRRHFKRKEAGDGVHDDSC-------RHRRPSIAVPTSRARRRSSVGLP----SSALTQRRRSSVQLQALPRINSSQPVH---------------------QKSSGRRRSSTTT----LKANPRFAVRRKKVGKLRNIDTHLLGPSMLLASLIQMTQEEEDDEEGRSPLPGQVELKGSSSKFRSHTDVLLSEGDSDS-----------------------------DDSSEHSEERQYSRIRKECLEQADGSDWGVKESGVLCQQDCLPLSVVAERVQAHPLIRVPRCLRRN-----SSHYGHAESG-PHVRYCRSSQRRRRRRVSTISK------AGSPWPGRGLPLPNRRSSCYRGPATFNPLLGAYYD----------------------------------------------------------------PRLESWSGFLSKAIAKAGVQDNAAQSG-------------------------------------------TITPAKSEPNKKICNTVDWTENAQLGQHVWFETSPAGDFCYVGESNCIAKSQQKSLPRHKCAACKISVHTECMNQL-DKINFRCKPTFKDPGTKNVRETPNMNHHWVHRRRQDGKCRQCGKGFQQKFSFHS-----KDIVAISCSWCKQAYHNKVNCFMMQRIDEPCSLGAHAAVIIPPTWIIRMRRQ---QASLKSSKRRKRTS--------------------LKAKPSKKLEQDGKWRNFVVRAIPSQHMKPLLVFVNPKSGGNQGTKIIRTFMWYLNPRQVFDLTQGGPREGLEMYSKVPNLRILVCGGDGTVGWILSVLDELQ--LNPQPAVAVLPLGTGNDLARTLNWGGGYTDEPVSKILSQVEDGIIVQLDRWNLSVEANLEASDEDKDEQQTDKLPIDVFNNYFSLGFDAHVTLEFHESREAKPERFNSRLRNKMFYAGTAFSDFLMGSSKDLSKHIKVVCDGTDLTSKIQDMKVLCLLFLNIPRYCAGTMPWGNPSENNDFGPQKHDDGLIEVIGFTMTSMATLQVGGHGERLHQCKEVTLTTFKPIPVQVDGEPCRLAPSVIHITRRNQANMLQKTKRRISLPQLYDQQPIAETVQIQVNRISMHDYEALHYDKEQLKEAAIPMGIITVPGNSDLETCRQHIERLHEEGDGMNTDTLHMPKLSPKWCFLDCTTADRFYRIDRGQEHLNYVSEISQDELFILDPELVTKETVGTSPGMPGAMETVVGGCGCSNSTDQFAFPACSPGPSPLCRVNETHAESQPESVSEEIDMHVQSDPESPTNLGVYRVHETHAESQLESLSPESDSHVQSDPGSPTKSGLYRRGAKNKISSRSNTLEEDSVNVQRLDTVWNKSDQDSTNLLFDAVKSGNLEKLEQMHEEGADLTVQDHLGCTILHQAVILGHKEIVKFITENAPACILDVTEKSTGETALHKAAALCHRTICCYLVDAGASLMKTDLQGETPKMYAERTRDYELAEYLENQQHHQMIQRDDHETAV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q09103-1", "uniprot_id": "DGK2_DROME", "id": "Q09103-1", "name": "Eye-specific diacylglycerol kinase", "aln": "MQQQQQPSIDQLPEPTASTSNSATTKPTIATATTSTTTTSGNNFHQQLQATTAATMQRLRTTFTRSRTPTGAEMKMQNSLEVPKQVRSASFDEMQLESQRASSSLLKQQSSSSASADERSSEAGFLQVPLAAHQQRSHSFDSATASAGSDDSGTFLEVPRRLKARRSSSTKTPPPCIHCHYLEEYERRMTAEQRYFIDHRELTALSYSNTSSEASEDEDEVEGHNAEEEEEGSAAIEDAEEETTEAATEEADEDPRTEVESEHDHDPDDDAALEMDIRIGNMSQGSSIEESRARLPRQMRRHTIGSSSVTSASEDEGLEGSDNGSPHFGNTLLPPQPTTPCGITFTLSPTNGDYPSPPHLPLDPGSPPISPCSSNSGRLPALAPIISTPCSSADADDAGAAMGLPVRARRRSISRQEAIFVEPTGNSLENVSHEEVDNSNTKSSVDTADSLDEASTMATCGSPGAAGGSGASSSHHNAFVVRDIYLMVPDLKRDRAASVDSCFSKLSSNAKTEELQPSADGCFLTVPNINATRSRSVDIVLPTDEQARYKALSMTGSTVTYADGRTASASNSRRPIRIVPDWTENAVQGEHYWKPTSASGDLC------CLNEECIKSGQRMKCSACQLVAHHNCIPFVNEKSTLACKPTYRDVGIRQYREQTTTHHHWVHRKLEKGKCKQCGKFFPMKQAVQSKLFGSKEIVALACAWCHEIYHNKEACFNQAKIGEECRLGNYAPIIVPPSWIVKLPTKGNFKSSIRVSNKNNAASGSGGGGAGGGAGGGGGKSKKQTQRRQKGKEEKKEPRAFIVKPIPSPEVIPVIVFINPKSGGNQGHKLLGKFQHLLNPRQVFDLTQGGPKMGLDMFRKAPNLRVLACGGDGTVGWVLSVLDQIQPPLQPAPAVGVLPLGTGNDLARALGWGGGYTDEPIGKILREIGMSQCVLMDRWRVKVTPNDDVTDDHVDRSKPN-VPLNVINNYFSFGVDAHIALEFHEAREAHPERFNSRLRNKMYYGQMGGKDLILRQYRNLSQWVTLECDGQDFTGKLRDAGCHAVLFLNIPSYGGGTHPWN---DSFGASKPSIDDGLMEVVGLTTYQLPMLQAGMHGTCICQCRKARIITKRTIPMQVDGEACRVKPSVIEIELLNKALMLSKRKHGRGDVQVNP----LEKMQLHILRVTMQQYEQYHYDKEMLRKLANKLGQIEIESQCDLEHVRNMLNTKFEES-------ISYPKVSQDWCFIDSCTAEHYFRIDRAQEHLHYICDIAIDELYILDHEAAT---MPQTPDQE-------------RSFAAFSQRQAQNERR------------------------------------------------------QMDQAQGRGPGSTDEDLQIGSKPIKVMKWKSPILEQTS------------------DAILLAAQSGDLNMLRALHEQGYSLQSVNKNGQTALHFACKYNHRDIVKYIIASATRRLINMADKELGQTALHIAAEQNRRDICVMLVAAGAHLDTLDSGGNTPMMVAFNKNANEIATYLESKQGTQPVDGWLDD---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . *.:. .*.:. .: . . * . * .. * .. * : :* * ::: :. . . .. .:... * . **:*.* *:* * *. :**:* *: . ** * **:**:: .* *: : :* .: ***:::: * :: ** . .******: :.***::*** * * :.:* *:***::*:**:: **.* ** :* * * ** :*.:::**:**:: : ::: *::.: :* . : .* :. . * *:::. ** : *::**:********* *:: .* *********:****: .*:*: *. ***:*.*********:**.**::: *:* *.*.:***********:*.*********:.*** .: . * :*** : . .* :. :. * .: :*::*:*****:*.***::*****:***:**:****:****:*. . .*::: . ::*:: : : *** *:* *::* .::***** * .** **. : . *** :**:*:* .:. **.* ** : **::. : * :.**:*****.*:: .* *.* *:* *:.* *: * ::::: *::*::** ***** *:: : :* : : .:.*** * :: .* :* .***:*. **.:::****.****:*: :*: **::*** * *. . :. .. ... . *: :: *.: .: *. :*. * .* :. . * ** * . :::*::: *. ::: .:: *:*.** ** :* ** :* *** * . * *:** * . . *:* ***.:* * :: .: ", "identical_positions": 321, "similar_positions": 294, "identity": "20.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111107-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6P7Q0-1", "uniprot_id": "ETKMT_RAT", "id": "Q6P7Q0-1", "name": "Electron transfer flavoprotein beta subunit lysine methyltransferase", "aln": "--MAFSLCWKAPRSQWS-FLQALNS-GFPLF-----PWRTVGSCLDLKMKAYLEENTEVTSSGSLTPEIQLRLLTPRCKFWWERADLWPYSDPYWAIYWPGGQALSRYLLDNPDVVRGKSVLDLGSGCGATAIAAKMSGASNILANDVDPIAGMAITLNCKLNGLNPFPILTKNILNTRQGKFDLIVLGDMFYDEDLADSLHLWLQNCFWAYGTRVLIGDPGRPQFSGHSIQHQLYQLAEYTLPEPTQQDNNGLTTSAVWDFHP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80ZM3-1", "uniprot_id": "ETKMT_MOUSE", "id": "Q80ZM3-1", "name": "Electron transfer flavoprotein beta subunit lysine methyltransferase", "aln": "--MAFSLCWKAPRSPWS-FLQAVNN-GSPLF-----LWRTVGSCLDPKMKAYLEENTEVTSSGSLTPEIQLRLLTPRCKFWWERADLWPYSDPYWAIYWPGGQALSRYLLDNPAVVRGKSVLDLGSGCGATAIAAKMSGASKILANDIDPIAGMAITLNCKLNGLNPFPVLTKNILNTQQGKFDLIVLGDMFYDEDLADSLHLWLQNYFWTHGTRVLIGDPGRPQFSGHSIRHQLYQLVEYTLPEPTQQENNGLTTSAVWDFHP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IXQ9-1", "uniprot_id": "ETKMT_HUMAN", "id": "Q8IXQ9-1", "name": "Electron transfer flavoprotein beta subunit lysine methyltransferase", "aln": "--MALSLGWKAHRNHCGLLLQALRSSGLLLFPCGQCPWRGAGSFLDPEIKAFLEENTEVTSSGSLTPEIQLRLLTPRCKFWWERADLWPHSDPYWAIYWPGGQALSRYLLDNPDVVRGKSVLDLGSGCGATAIAAKMSGASRILANDIDPIAGMAITLNCELNRLNPFPILIQNILNLEQDKWDLVVLGDMFYDEDLADSLHQWLKKCFWTYRTRVLIGDPGRPQFSGHSIQHHLHKVVEYSLLESTRQENSGLTTSTVWGFQP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A3KP85-1", "uniprot_id": "ETKMT_DANRE", "id": "A3KP85-1", "name": "Electron transfer flavoprotein beta subunit lysine methyltransferase", "aln": "MYRRIIMCFRS-RATLNSFQRGMCCSTRRYV-------SSTGS--EDDIKNFIIDNTEIVNSQSLTPEISLRLFTPTCRFWTENPEFWPFPDPYWAIYWPGGQALARYLLNNPEVSAGRKVLDLGCGCGASAIAARLSGASCVVANDIDPIAAIATKMNCELNNLAPLPCVTDNMIGSETDGWDLILLGDMFYDEALADGLHQWLQTCTNTHGTQVLIGDPGRAQFEDHNIRRSLHRLAHFQLPDSVKEENYGLTSSAVWRYNCKPDH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : ::: * . : :.: . .** : .:* :: :***:..* ******.***:** *:** *..::**..**************:****:** * *:.*****.****:****::**** ::***:****.:* .:**:** * *:* : .*::. . . :**::******** ***.** **:. :: *:********.**..*.*:: *:::..: * :..:::* ***:*:** :: ", "identical_positions": 119, "similar_positions": 85, "identity": "44.4%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111111-11", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9P2P6-1", "uniprot_id": "STAR9_HUMAN", "id": "Q9P2P6-1", "name": "StAR-related lipid transfer protein 9", "aln": "MANVQVAVRVRPLSKRETKEGGRIIVEVDGKVAKIRNLKVD----NRPDGFGDSREKVMAFGFDYCYWSVNPEDPQYASQDVVFQDLGMEVLSGVAKGYNICLFAYGQTGSGKTYTMLGTPASVGLTPRICEGLFVREKDCASLPSSCRIKVSFLEIYNERVRDLLKQSGQKKSYTLRVREHPEMGPYVQGLSQHVVTNYKQVIQLLEEGIANRITAATHVHEASSRSHAIFTIHYTQAILENNLPSEMASKINLVDLAGSERADPSYCKDRIAEGANINKSLVTLGIVISTLAQNSQVFSSCQSLNSSVSNGGDSGILSSPSGTSSGGAPSRRQSYIPYRDSVLTWLLKDSLGGNSKTIMVATVSPAHTSYSETMSTLRYASSAKNIINKPRVNEDANLKLIRELREEIERLKALLLSFELRN-----FSSLSDENLKELVLQNELKIDQLTKDWTQKWNDWQALMEHYSVDINRRRAGVVIDSSLPHLMALEDDVLSTGVVLYHLKEGTTKIGRIDSDQEQDIVLQGQWIERDHCTITSACGVVVLRPARGARCTVNGREVTASCRLTQGAVITLGKAQKFRFNHPAEAAVLRQRRQVGEAAAGRGSLEWLDLDGDLAASRLGLSPLLWKERRALEEQCDEDHQTPRDGETSHRAQIQQQQSYVEDLRHQILAEEIRAAKELEFDQAWISQQIKENQQCLLREETWLASLQQQQQEDQVAEKELEASVALDAWLQTDPEIQPSPFVQ-SQKRVVHLQLLRRHTLRAAERNVRRKKVSFQLERIIKKQRLLEAQKRLEKLTTLCWLQDDSTQEPPYQVLSPDATVPRPPCRSKLTSCSSLSPQRLCSKHMPQLHSIFLSWDPSTTLPPRPDPTHQTSEKTSSEEHLPQAASYPARTGCLRKNGLHSSGHGQPCTARAALARKGASAPDACLTMSPNSVGIQEMEMGVKQPHQMVSQGLASLRKSANKLKPRHEPKIFTSTTQTRGAKGLADPSHTQAGWRKEGNLGTHKAAKGASCNSLYPHGPRQTAGHGKAVKTFWTEYKPPSPSRASKRHQRVLATRVRNITKKSSHLPLGSPLKRQQNTRDPDTMVPLTDFSPVMDHSREKDNDLSDTDSNYSLDSLSCVYAKALIEPLKPEERKWDFPEPENSESDDSQLSEDSLAEKRYQSPKNRLGGNRPTNNRGQPRTRTRASVRGFTAASDSDLLAQTHRSFSLDSLIDAEEELGEDQQEEPFPGSADEIPTETFWHLEDSSLPVMDQEAICRLGPINYRTAARLDAVLPMSSSFYLDPQFQPHCELQPHCELQPHCELQPHCEQAESQVEPSYSEQADSLQGMQLSRESPLMSMDSWFSCDSKINPSSPPGIVGSLCPSPDMQEFHSCKGERPGYWPNTEELKPSDAETVLPYSSKLHQGSTELLCSARDEHTASAADTSRLSLWGIQRLIQPGADGTFQGRCIPDMTQQGSSEASHNSSVSNVLAASATTLTHVGSTHERDWSALQQKYLLELSCPVLEAIGAPKPAYPYLEEDSGSLAQASSKGGDTLLPVGPRVSSNLNLNNFPVHLSRIRRLRAEKEQDSLNAKLEGVSDFFSTSEKEASYDETYSADLESLSASRSTNAQVFATENAIPDSMTEACEVKQNNLEECLQSCRKPGLMTSSDEDFFQKNACHSNVTTATKADHWSQGWAPLRKNSAVQPGQLSPDSHYPLEEEKTDCQESSKEAVRRHINVSFALPSGPELYLHSAPWNPLSSSLQPPLLETFYVTKSRDALTETALEIPACREVRVPSPPPREAWGFGHNHQALQGAYLKNNLPVLLQNQNSKIASSQQVTAEIPVDLNTREVIRESGKCPGNITEESHDSVYSSVTQNRHFLPSTSTKVCEFENQVVILNKKHSFPALEGGEVTAQSCCGASSDSTESGKSLLFRESEAREEEELDQNTVLRQTINVSLEKDMPGESAVSLKSRSVDRRVSSPVMVAQGGGPTPKWEGKNETGLLEKGLRPKDSSEEFKLPGTKPAYERFQLVACPQERNPSECKSQEMLNPNREPSGKKQNKRVNNTDEMARLIRSVMQLENGILEIESKQNKQVHASHTPGTDKELVFQDQKEQEKTDHAFRPDSSGNPLPSKDQPSSPRQTDDTVFRDSEAGAMEVNSIGNHPQVQKITPNPFRSREGVRESEPVREHTHPAGSDRPARDICDSLGKHTTCREFTNTSLHPQRMKALARALPLQPRLERSSKNNGQFVKASASLKGQPWGLGSLEELETVKGFQESQVAEHVSSSNQEEPKAQGKVEEMPMQRGGSLQEENKVTQKFPSLSQLCRDTFFRQETVSPLLSRTEFCTAPLHQDLSNTLPLNSPRWPRRCLHVPVALGISSLDCVLDLTMLKIHNSPLVTGVEHQDQSTETRSHSPEGNVRGRSSEAHTAWCGSVRSMAMGSHSQSGVPESIPLGTEDRISASTSPQDHGKDLRITLLGFSTSEDFASEAEVAVQKEIRVSSLNKVSSQPEKRVSFSLEEDSDQASKPRQKAEKETEDVGLTSGVSLAPVSLPRVPSPEPRLLEPSDHASMCLAILEEIRQAKAQRKQLHDFVARGTVLSYCETLLEPECSSRVAGRPQCKQIDQSSSDQTRNEGEAPGFHVASLSAEAGQIDLLPDERKVQATSLSADSFESLPNTETDREPWDPVQAFSHAAPAQDRKRRTGELRQFAGASEPFICHSSSSEIIEKKKDATRTPSSADPLAPDSPRSSAPVEEVRRVVSKKVVAALPSQAPYDDPRVTLHELSQSVPQETAEGIPPGSQDSSPEHQEPRTLDTTYGEVSDNLLVTAQGEKTAHFESQSVTCDVQNSTSASGPKQDHVQCPEASTGFEEGRASPKQDTILPGALTRVALEAPTQQCVQCKESVGSGLTEVCRAGSKHSRPIPLPDQRPSANPGGIGEEAPCRHPREALDGPVFSRNPEGSRTLSPSRGKESRTLPCRQPCSSQPVATHAYSSHSSTLLCFRDGDLGKEPFKAAPHTIHPPCVVPSRAYEMDETGEISRGPDVHLTHGLEPKDVNREFRLTESSTCEPSTVAAVLSRAQGCRSPSAPDVRTGSFSHSATDGSVGLIGVPEKKVAEKQASTELEAASFPAGMYSEPLRQFRDSSVGDQNAQVCQTNPEPPATTQGPHTLDLSEGSAESKLVVEPQHECLENTTRCFLEKPQFSTELRDHNRLDSQAKFVARLKHTCSPQEDSPWQEEEQHRDQASGGGEGFAQGVNPLPDEDGLDGCQILDAGREEVAVAKPPVSKILSQGFKDPATVSLRQNETPQPAAQRSGHLYTGREQPAPNHRGSLPVTTIFSGPKHSRSSPTPQFSVVGSSRSLQELNLSVEPPSPTDEDTQGPNRLWNPHLRGYSSGKSVARTSLQAEDSNQKASSRLDDGTTDHRHLKPATPPYPMPSTLSHMPTPDFTTSWMSGTLEQAQQGKREKLGVQVRPENWCSQMDKGMLHFGSSDISPYALPWRPEEPARISWKQYMSGSAVDVSCSQKPQGLTLSNVARCSSMDNGLEDQNSPFHSHLSTYANICDLSTTHSSTENAQGSNEAWEVFRGSSSIALGDPHIPTSPEGVAPTSGHDRRPQFRGPSGEADCLRSKPPLAKGSAAGPVDEIMLLYPSEAGCPVGQTRTNTFEQGTQTLGS---RRHWSSTDISFAQPEASAVSAFDLASWTSMHNLSLHLSQLLHSTSELLGSLSQPDVARREQNTKRDIPDKAPQALMMDGSTQTTVDEGSQTDLTLPTLCLQTSEAE---PQGANVILEGLGSDTSTVSQEEGDVPGVPQKREAEETAQKMAQLLYLQEESTPYKPQSPSIPSSHLRFQKAPVGQHLPSVSPSVSDAFLPPSSQPEESYCLVVSSPSPSSPHSPGLFPSTSEYPGDSRVQKKLGPTSALFVDRASSPILTLSASTQEPGLSPGSLTLSAPSTHPVEGHQKLDSSPDPVDAPRTPMDNYSQTTDELGGSQRGRSSLQRSNGRSFLELHSPHSPQQSPKLQFSFLGQHPQQLQPRTTIGVQSRLLPPPLRHRSQRLGNSFVPEKVASPEHCPLSGREPSQWQSRTENGGESSASPGEPQRTLDRPSSWGGLQHLSPCPVSELTDTAGLRGSALGLPQACQPEELLCFSCQMCMAPEHQHHSLR-DLPVHNKFSNWCGVQK--GSPGGLDMTEEELGASGDLSSEKQEQ------SPPQPPNDHSQDSEWSKREQ----IPLQVGAQNLSLSVELTEAKLHHGFGEADALLQVLQSGTGEALAADEPVTSTWKELYARQKKAIETLRRERAERLGNFCRTRSLSPQKQLSLLPN-KDLFIWDLDLPSRRREYLQQLRKDVVETTRSPESVSRSAHTPSDIELMLQDYQQAHEEAKVEIARARDQLRERTEQEKLRIHQKIISQLLKEEDKLHTLANSSSLCTSSNGSLSSGMTSGYNSS------------------PALSGQLQFPENMGHTNLPDSRDVWIGDERGGHSAVRKNSAYSHRASLGSCCCSPSSLSSLGTCFSSSYQDLAKHVVDTSMADVMAACSDNLHNLFSCQATAGWNYQGEEQAVQLYYKVFS-PTRHGFLGAGVVSQPLSRVWAAVSDPTVWPLYYKPIQTARLHQRVTNSISLVYLVCNTTLCALKQPRDFCCVCVEAKEGHLSVMAAQSVYDTSMPRPSRKMVRGEILPSAWILQPITVEGKEVTRVIYLAQVELGAPGFPPQLLSSFIKRQPLVIARLASFLGR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F0X8-1", "uniprot_id": "E7F0X8_DANRE", "id": "E7F0X8-1", "name": "", "aln": "MANVKVAIRVRPLNTRESLDGGRLAVQVEDKVVRVRNVKLEGRLDGRSEGLADSREKLIEFGFDYCYWSVDPAASNYASQEEVFQDLGVCVLSGASEGYNVCLFAYGQTGSGKTHTMMGTPDSIGLTPRICQGLFRSGVESSDG-QSCRVEISFLEIYNERVRDLLRGVEQKKPAPLRVREHPEKGPYVQGLSQHVVTDYKQAVDLLEEGIANRITAATHVHDASSRSHAIFTIQYTQAILENNLPSEIVSKINLVDLAGSERADPQYCRDRITEGANINKSLVTLGIVISALAQNCQMSSSSQSINSMLSEGEGSTVGSQSSSLS---GSGRRHCFIPYRDSVLTWLLKDSLGGNSKTIMIATVSPSSSSYNETLSTLRYAAHARNIVNKPRVNEDANVRLIRELREEIDRLKSMLLTFEMQRNPSPSLSDERESSFSDIVLQNEMKVEQLTKDWSDSWHDKRALLERYNVDINQDRAGVLIHSLQPHLIALEPDVLSTGVTIYHLREGVTRIGPQGENLEDPHIVLP---EGSSCVIENKSGVVTLKPVSGHICMVSEREITEPCRLAQGAVITLGGLHRFRFNHPAEAAVLRERRRTSEGGLVFTSAELNQPMPDARVPGAGCD--------------------ERGGGTAPRQRLEEQQWYIECLREEIQMEQKRAERDLEREQARLRQQHNEIQQWILQENQRLAAHREKTTLESGVQTDLVLSVTSESQEVRDAETVPPSISMGDRKRVVQEELLKHHALRRAENRVRRKRLHYQLEKIARKRHLLEAKRELQRLENLHLEG---CNETSSLELAYSLKLRGRPMTLRRHSFSADLLSRLYPQHTPIFSQFLKRNKSSDFTYTKWESDECLQDQKIRRRSNTMPSRYDQGSSSWASFSDNLESPLKDSSSAEATKAKTASTRLLVKKSTSDQDKHCLDSNTKAVRKVLPVIKQKSLVKGTKSPSQSGNKGLDNIRKVFSNSVGFGIRTALAKVFRKPPSGSRGHKSVKSMNKALRKFNEKSIKNKTGKDLEKIHKQSPIKSAMSYESLGRVGTLKYQHQRHWHSAEALTSTKQSVEVQNKAAGWVEHGDVE--------DSNRSSDCESIFSLDSLSSAYARALAEQLQQEE-----CDSSEAESEDSQMSQDSLVMENSWKHMTARPMLRFNKVPSHLTVSTSCGSPSISNKLET--------------------------------KISKDVPAEVYWSLNGS---------------------------------------------------QKLKTENGQGMAKGPSSLSFLASESRPCSGASNRETENPLALTDAWSSTDAADSPR----------------------------------------------------------------------------------------------------------------------------IIRASGHFKQDPPTLIESRSLDLIGNKNDLESQSSPCSDTTQGENATLESNDTSFENTLLLD--------NHESVPTFIPGIQDLTAEKDP----CTIHTVYDFTDASLDGVACTNKPTAEPLNTIVTEALLIDCSSKDGDISTSSSISKCFLVN------------------------------------------------------------------STKEDSDIREDNPSSSHDHPSVCQVPPYNN------------AGNSEIKISETAKVLNELHSIASNGQTNAQCDEEKDRS-----------------------------YTKQRTKMDCERYTKDYALNIKQLEKHDEKD--------------SSFSRDGECFIVQPVTESCQTKGIVGYLDAESALLNSDQEQSACSSINSESVTSVSLLENLPTRMQNSDQDKEMKSASSASDAYRALISKDHIS-------------------------------------------------------------IFRNDCTACDNGLTQTNCTSLKSFSS-----------------------------------------------------------------------------------------------------------------PEIKNITENSKEHR-------------------KDAVQIIDRKTLNNRYFQMSDTAINDKISEVVKEHFNLSLREDCG------------------------------EDYKLDSKKKISSLTKLDEFKYETNHHEYDYKSMQDGHCESSCSQLFP---------------------------------------------------------FSCMAISTDNTIVLNGNTESKNLLPTKDQAFLNSSGTEEATDR--KTEGKVEQCGYIN-------------EDVESVLYCTIESQGTFESMLPCVKETVIGLNTSK--------------------------------------------------------------------------------------------ENIIVCTELRKDYSDAANPIKRNCCTKKQVMENGSPTVLKPVVCKHAQATQTIQITNEMDKE---------------------------QKVNQCAQMKNETKLNQTWPTSKEMHKFYEQPSIHKTSGLLNELR---------CSASEKFLMEMSTPVESSKRDNLQASLP--------------------------------TKTTVKQTVSLETERDLADTWQKS---------MDDSTGILPN---LEVQNKKTCSHNSSTSSMEHWNSSEDD--------------------------------------------------------------------SYPVPEVRP------------------------------LSKLAFYEFGPRNHEKPCDEPCAEHSLKNYATMISS-----------------------------------CDNKDKVRSAEHIHIKKDAGNSDLG--------------------------QRSQKPQIHNKLIEKTDKDLQSERQFICTSNDLKTTMKSQCSDDHIKANQFCD-------------NQQMKNQEPCMPKNCHSTSKSLANTSSHVEVYHNAKHSPNSQNTKECYDNQCQSTDTIR---------------REHCTAADHTKHFVSDGNVDKHKGGKRRYRRAHFMAPP----------------------------SSSTDSTSELSLDENTTFKSHTSRKKPLLKGNPLSNSQNANGKHKNPVLDEQNKSSASPDCSKSLDTQKRYTKKPNIGVSP--------------------------SVVGALIHREAGIKTTACQQKNGSTVKIQP-------------TKIIETKHNKNVTLGKNGSSDDVLVDCVEVHGNLVDTVSDRKDSAMHFASSDINPYIHTRTAIGTNPAVHKKQAFGSVANISCHHSPPSSSNKNMTRCCSVDNGLNIQDCPFSSHLSAYVNNKGLSSTLSSNGYSRDQISSEPLLKATS----------LSSSGFDKQTPNDLKCESCNDASEELCN----------CSGQVDEIVLVYSSEYESPE-QPNPSTCDQGTQTIKANKDLKTKSRHRRSSTQTPLSKPGNSAQTTWASLQNMSEHLSDLIHNTSDLLGNIQCMRTG--EKPSKHDLPKPCFQVSTAHSGSNYKRDCCTQTSLDIGVQTEIASASKNATAHEVNVIVKLIGSDICSVSQLDGEAKILKNNYESEQAYERIKSMPDLR-------PRGSKVTGSQNGLTPSQRVISLDTVVPNQESSTLEAFESSKVDPSFKRSLPSYLEAKHSNMKLEKNQTCTRNVDLKNGFSKQVMLMDRACSPILTLKAAR-------YSQQKLLQTNLKTTKGQKECSNLYSMPLKCHKISNYEQMALDQQKACRNAKTISKSLSSMNFESLSNLACPN-------LDGSEDFSNAVCPRMYNEGNKYYHEVEDRVTSKQKTCSPTHLQRTSYSTSSGTIDVQLASSSVKVRQSKMESSD-KPNLSTVNGQLSLRSSEYITKSWDTVQHQEDDVMSLLPSECNTDVLVSISPLAGISTLKEQQWIPDDLPMHNKFTNWSGINQPQSMLGKVKATNEQLNPSYRQPVDSQSPSLFYRLESTEKTDRRTQEIEKLRKEREQVLASLHVDQSSHQLTVELKEARLHYGQGETDTLLKMLKSGS-----KDLYSACNKEELLNRHRRSIESLRKERESRLQMCRRARSLSPSKHHVPANNEKEQSRRSSDLPSRRREYLQQLRQEIVETSRVPDLPRQEGHCPSDIELLLRDYSRAREEARAEIARARDRLRERTEQEKRRLQQQTLSKAMKDDLRFRTRISNSTLCTGSNLSLSSGPTSGYNSSNAAILKDITSPLIQVNGVSDFKIRTRPPLIPLQTSKAQRKWLSVQDVSLETSVIGYEPESSSTPSSPPCARQRTLSFGSPSSMLTSYQDIADCTLASAISEVYLASGGDVRNLLAGKAAAGWRHQGVERGIQVFYKATSRTSAHGFLGAVELDRPLSSLWSIVRDHSKIHLYNESVKSAWTRP-LDESTQLVYLLTNMTNCQLKQPRDFCCLSTESKQDDMRVLAMQSVFEETLPRPSADTIRGEMLPSAWILQPSHRNGREAVTVIYLLQVDLGSPSLAPRLLNAVSRKQAAVIADLDSFFSL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:**:*****..**: :***: *:*:.**.::**:*:: .*.:*:.*****:: **********:* .:****: ******: ****.::***:*************:**:*** *:*******:*** :.:. .***:::**************: ***. .******** *************:***.::*****************:***********:*************:.****************.**:***:*****************:****.*: **.**:** :*:* .* : *..*. * ...**:.:************************:*****: :**.**:******: *:**:**********::*********:***::**:**::. :*. :..:.::*****:*::******::.*:* :**:*:*.****: ****:*.* ***:*** *******.:***:**.*:** ..: *: :: * . *.* . .***.*:*. * * *. **:* .***:******** ::*************:**:..*.. * * : * .. * . *.* *: * ::::** *:* **.:* *: ** ::** :** : ** :* ** :*:*: **: ::: :. .:.:* **: :: *.* *..: .:****: :**::*:** **..****:: :***:* :*::****::.*::* .* :*.. *: . .: * : * *: .** .:* * : .:: ..* .: :. . .::. .. . .: * :.. . . : .. : .:: * * **: . :.:. . : : ** *.::. . : : . . .: *:. : :** . . : : : ::* .. :. .: : .* ..: : : ** : : :: : * .* *. : : ... * *.. ..* ** :* :******..**:** * *: ** :..::**:***:*:***. :. . . * .: .: . * .. .:: :: :.::*:*.:* *:.* : : * :. *.:. **. . . : . *.** *:* * *: .* : :... .::* .:* :. *:* : . ..*. : :..:* . .:. :*** * :..*..:. *: * ***: ..:. * ** .:* . .: :. :*: . .:.: : :.:. *. * : : . * :*.:* :*.. .: : * .*. . * . :.. : : ** * :. .:::... . * * : * .:: . ..:: * : .:::: * *.. * :.. *: .. *: *: :. * *: : :: : : :..* . * *.. :.* * .:: :::*:.. : :: .. :.** . * : .** : . ::*.* : :.. *::::** *. . * : * :* * :. ::::*::: : :.: . : *. * : . :.:: .. : * :: :* * : : .* : . : *.. :* ** :*.: * *:: *: . : :**: . * : *.. * .:*.:. ** :. *.: *.:. : :. :: *::*:.**: *:* .. **: * . . . :. : : *. * **: : :.: * ** : ..:. .: * . .:.* . : : : . :: :* *.:: .*:** : : .:. .*. * * .. * * :.*:*. ** ..:. *.* :* : * :.: : .*.:**. .:*.: : : **:. . . *:*: ** *: . * ..: ** :**:.:.: .:* * *:..:: . .:*:.:. .*:. : .. *:::. :.:: .* . : .: :. .:: . : *. :.: * *: : :* * . :.. . . .* . : :**..*: :: * : :* :. *:. :.: .: : *: .** . : :. * *.. ...: :** :* * :. :.*. * .*. . .:: .. ..::. ::* :** . *: ..* :: *:.*.* **. : :: * . :.::.: .:*:* : : ::: ...... *. .::: : : *: . : *: ... :**.****.** . . . *: **..::** :.* . : .*::**.*:****: *:.** ****:*.* .**:* **. ::.. .: :::.:* *..*. : :* : : . :.* * .:* ****:*:*.** .* *....* :*****: : : * * :*. * . ::*:*::*:* ***:*:*.**:***.:. .. *: :*:*:*. . *. ...:: . * :**.* : . :* :: .: .***:: :*** .:*** :*:. : :: *:*:: ::: .: *: *:...:..*: : : * :* *. ..: * . ...: . .: * ** ..: ..: ...: . *: ....:::***.******.*: * :. . ** *. .: :.**.* : : : *. .::.:* . :* * : : : *.. . . : :.. :..* :: * :: ..:.. ** * * : : :*. ...: : .*. .. .*: . . * * . **. *:.: *:.:* ::. :::: : ***:****:**.*::: . * :. *:*:*..* . :.*. ...: .: ::*: * ::*: .*:*. .. .*:***.**:**:* **:*:**::*:**: * :.. :** *::::**:**:** .** *:*****.*: * *: . **************:::***:* *: :..* ******:*:**.:*:***:.*******:********* *::*: :*: :*:: :::* ..*:***.** ***** ******* . :. : : * :*. .: : : : * *.: :. * .* .*. . : . :.: :****:*. .: :::::* *...:::**:: :*:***.:** *:.:*::**. * .: ****** :.:*** :*: * * : ** :.:::* : : :* .****: * * * *********:..*:*:..: *:* ***:: ::**** . :***:********* :*:*.. **** **:**:*.:.*:**.:. ::*. *** * **:. ", "identical_positions": 1101, "similar_positions": 1301, "identity": "23.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111111-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60239-1", "uniprot_id": "3BP5_HUMAN", "id": "O60239-1", "name": "SH3 domain-binding protein 5", "aln": "MDAALKRSRSEEPAEILPPARDEEE--EEEEGMEQGLEEEEE-VDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGEYKMALKNLEMISDEIHERRRSSAMGPRGCGVGAEGSSTSVEDLPGSKPEPDAISVASEAFEDDSCSNFVSEDDSETQSVSSFSSGPTSPSEMPDQFPAVVR----------------PGSLDLPSPVSLSEFGMMFPVLGPRSECSGASSPECEVERGDRAEGAENKTSDKANNNRGLSSSSGSGGSSKSQSSTSPEGQALENRMKQLSLQCSKGRDGIIADIKMVQIG-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z131-1", "uniprot_id": "3BP5_MOUSE", "id": "Q9Z131-1", "name": "SH3 domain-binding protein 5", "aln": "MDTALKRSRSDEPAELPPPAREVEEKEEEEERMEQGLEEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKLDELAKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLALAKGEYKAALKSLERISDEIHERRRSNAMGPRGCGVGAEGSIASVENLPVSKPEPDAISVASEAFEDDNCSNLVSEDDSETQSVSSFSSGPTSPSEMPDQFPAVAR----------------PGSLDLPSPVSLSEFGMMFPILGPRSECSGASSPECEVERGDRAEGAENKMSDKANNNRVLGSTNGGSGRSRSQSSTSLESQALETRMKQLSLQCSKGRDGIIADIKMIFIFYTFLQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2L4V3-1", "uniprot_id": "A0A0G2L4V3_DANRE", "id": "A0A0G2L4V3-1", "name": "SH3 domain-binding protein 5", "aln": "MNEPEKENKSDEDSESL----------------------EEEEVDPRIQGELEKLNQSTDNINQWETELEDSRQKFRAVLVEATVKLDEQVKKIGKAVEESKPYWEARRAARQAQVEAQKATQEYQRAIEILRAAKETIALAEERLLEEDSRQFDSAWQEMLNHATQRVMEAEQSRTRSEMEHRETAAKYNAAISHMRQLEKKLKRTINKSRPYFELKAKYYLQLEQLKRRVDERQAKLTQAKAEYRSALRNLETISDEIHERRRLSAIGPRGRGVGAEDDGATIDDITNFKMESDGISMMSVNLEDG-CNGTTSEEDPETSESSCSVSSTSVPLDMPCPYPSSASPYPLLSSSCPYPSSGCPDMLQMPGSGSLEGFERVSPVLGPRSECSGASSPDCEQERGERAEGAEVKPEQTTNNSSQKSSDLEKSLRSLSLQAPDDNHNENETDARSFTVSCN------TPAVLLNSV------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . *..:*:* :* *** *****************:**: ******:*****:*********** .********:*********.*****:*******::*** *:********:***:****:*.***********************::****: *:****:****:.:**********:****:**********:******: **: ****: **.**: **:.** ********** .*:**** *****.. ::::::. * *.*.**: * :**. *.. .**:*.**.. *. *..: * :** :*: . *. *::*.. **. * : *:*************:** ***:****** * .:.:**. .* . * * .:.. : : *. :.:::.*. . : : : ", "identical_positions": 257, "similar_positions": 106, "identity": "53.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111111-9", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R523-1", "uniprot_id": "KCNG3_RAT", "id": "Q8R523-1", "name": "Voltage-gated potassium channel regulatory subunit KCNG3", "aln": "MTFGRGGAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTHTFHAAEE-------LGREQPRPTGPEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLCASTLPDWRAAAADNRSLDDRSRYSASPGREPSGIIEAICIGWFTAECIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFASIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELKFRSARYSRSLSAEFLN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59053-1", "uniprot_id": "KCNG3_MOUSE", "id": "P59053-1", "name": "Voltage-gated potassium channel regulatory subunit KCNG3", "aln": "MTFGRGGAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTHTFHAADE-------LGREQPRPAGPEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLCASTLPDWRAAVADNRSLDDRSRYSASPGREPSGIIEAICIGWFTAECIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVIKLARHFIGLQTLGLTLKRCYREMAMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFASIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELKFRSARYSRSLSAEFLN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TAE7-1", "uniprot_id": "KCNG3_HUMAN", "id": "Q8TAE7-1", "name": "Voltage-gated potassium channel regulatory subunit KCNG3", "aln": "MTFGRSGAASVVLNVGGARYSLSRELLKDFPLRRVSRLHGCRSERDVLEVCDDYDRERNEYFFDRHSEAFGFILLYVRGHGKLRFAPRMCELSFYNEMIYWGLEGAHLEYCCQRRLDDRMSDTYTFYSADEP----GVLGRDEARPGGAEAAPSRRWLERMRRTFEEPTSSLAAQILASVSVVFVIVSMVVLCASTLPDWRNAAADNRSLDDRSRYSAGPGREPSGIIEAICIGWFTAECIVRFIVSKNKCEFVKRPLNIIDLLAITPYYISVLMTVFTGENSQLQRAGVTLRVLRMMRIFWVIKLARHFIGLQTLGLTLKRCYREMVMLLVFICVAMAIFSALSQLLEHGLDLETSNKDFTSIPAACWWVIISMTTVGYGDMYPITVPGRILGGVCVVSGIVLLALPITFIYHSFVQCYHELKFRSARYSRSLSTEFLN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QJ67-1", "uniprot_id": "A0A8M9QJ67_DANRE", "id": "A0A8M9QJ67-1", "name": "Voltage-gated potassium channel regulatory subunit KCNG3", "aln": "MKFGKN---ICILNVGGTKYAFTREVIKDFPLRRVSRLHSCSSEKEVLEVCDDYDRERNEFFFDRHSEAFVFIMLYVR-SGKLRFVPQMCELSFYNEMIYWGLESSHLEFCCQRRLEDRMSDTYTYFSEDDMKAEVESRGEEEQVSRFAPDRGSARWLERMRRTFEEPASSIAAQILASVSVVFVIMSMVILCASTLPDW--DTAKNNTVEEHR------------IIEAVCIGWFTAECIVRFIVSRDKCEFVRRPLNIIDLLAITPYYVSVAMTALTGENPQLQRAGVTLRVLRMMRIFWLIKLARHFLGLQTLGLTLRRCYREMVMLLVFVCVAMAIFSALAQLLEHGLDLETSNEDYASIPASCWWVIISMTTVGYGDMYPITIPGRVLGGVCVVSGIVLLALPITFIYHSFVQCYHELKFRSARCVRSLSSEFLN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.**:. :*****::*:::**::************.* **::**************:********* **:**** *****.*:****************.:***:******:******:*:.: :: *.:: . . * *************:**:**************:***:********* .*.*.::::: ****:****************::*****:***************:** **.:****.*******************:*******:*********:******.*****:**********:*************:*::****:********************:***:************************************* ****:****", "identical_positions": 328, "similar_positions": 66, "identity": "74.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111114-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A3W9-1", "uniprot_id": "D4A3W9_RAT", "id": "D4A3W9-1", "name": "Protein Wnt", "aln": "MLPPVPSCLGLLLLLLLCPAHVGGLWWAVGSPLVMDPTSICRKARRLAGRQAELCQAEPEVVAELAR-GARLGVRECQFQFRFRRWNCSSHSKAFGRVLQQDIRETAFVFAITAAGASHAVTQACSMGELLQCGC------------------------------------QAPRGRAPPRPSGLLGTPGPPGPTGSPDA------------------------SAAWEWGGCGDDVDFGDEKSRLFMDAQHKRGRGDIRALVQLHNNEAGRLAVRSHTRTECKCHGLSGSCALRTCWQKLPPFREVGARLLERFHGASRVMGTNDGKALLPAVRTLKPPGRADLLYAADSPDFCAPNRRTGSPGTRGRACNSSAPDLSGCDLLCCGRGHRQESVQLEENCLCRFHWCCVVQCHRCRVRKELSLCL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P22727-1", "uniprot_id": "WNT6_MOUSE", "id": "P22727-1", "name": "Protein Wnt-6", "aln": "MLPPVPSRLG-LLLLLLCPAHVDGLWWAVGSPLVMDPTSICRKARRLAGRQAELCQAEPEVVAELAR-GARLGVRECQFQFRFRRWNCSSHSKAFGRVLQQDIRETAFVFAITAAGASHAVTQACSMGELLQCGC------------------------------------QAPRGRAPPRPSGLLGTPGPPGPTGSPDA------------------------SAAWEWGGCGDDVDFGDEKSRLFMDAQHKRGRGDIRALVQLHNNEAGRLAVRSHTRTECKCHGLSGSCALRTCWQKLPPFREVGARLLERFHGASRVMGTNDGKALLPAVRTLKPPGRADLLYAADSPDFCAPNRRTGSPGTRGRACNSSAPDLSGCDLLCCGRGHRQESVQLEENCLCRFHWCCVVQCHRCRVRKELSLCL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6F9-1", "uniprot_id": "WNT6_HUMAN", "id": "Q9Y6F9-1", "name": "Protein Wnt-6", "aln": "MLPPLPSRLGLLLLLLLCPAHVGGLWWAVGSPLVMDPTSICRKARRLAGRQAELCQAEPEVVAELAR-GARLGVRECQFQFRFRRWNCSSHSKAFGRILQQDIRETAFVFAITAAGASHAVTQACSMGELLQCGC------------------------------------QAPRGRAPPRPSGLPGTPGPPGPAGSPEG------------------------SAAWEWGGCGDDVDFGDEKSRLFMDARHKRGRGDIRALVQLHNNEAGRLAVRSHTRTECKCHGLSGSCALRTCWQKLPPFREVGARLLERFHGASRVMGTNDGKALLPAVRTLKPPGRADLLYAADSPDFCAPNRRTGSPGTRGRACNSSAPDLSGCDLLCCGRGHRQESVQLEENCLCRFHWCCVVQCHRCRVRKELSLCL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RQZ6-1", "uniprot_id": "A0A8M1RQZ6_DANRE", "id": "A0A8M1RQZ6-1", "name": "Protein Wnt", "aln": "MLS--KQKHVTWFHVILFTTLIPLQRRVNGNPLVMDPNSICRKTRMLAGRHTDLCQSQPEIIQEVAK-GARLGIRECQHQFHNHRWNCTSQGRNLAKILQQDIRETAFVYAVTAAGVMHAVTQACSQGALPQCGC------------------------------------VTLQSSSETYR---VSPAEEVLIQASSLH------------------------DWHWEWGGCGDDVDFGYEKSRQFMDIRQRKGKSDIRSLIDLHNNEAGRVAIQIQMRTECKCHGLSGSCTLRSCWKKMPLFRQVGDQLMQSFHTAVRVMGGNDGKSLVSIDPDAPPLDANVLIYSAESPDFCKANHRSGTEGTGGRACNRTETGPGGCDSLCCGNGFADFTVEEEENCECRFHWCCEVQCQTCSQRKNVSLCL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VM26-1", "uniprot_id": "Q9VM26_DROME", "id": "Q9VM26-1", "name": "Protein Wnt", "aln": "------MRLLMVIAILIFAMPMTGFGWAEGTNILLDPNLMCKKTRRLRGKLAEICRHDSALLKEIIINGINLGFRECEFQFRNRRWNCTVLRKSMRKILMRDSRETGFVNAITAAGVTYAVTKACTMGQLVECSCDKAHMRRNGGQPQMVTAATAEAALERQQQAAMLRQQMPLQDQHPSQRLSRMNNASTMTDIAPVEHRGGRNRRPGGRRGRRKFWDNIKFPEGQWEWGGCSDNVNFGLRHSRVFLDAKQRQRRSDLGTLVKFHNNNAGRLAIRDAMRLECKCHGLSGSCTVKTCWLKMPPFREVAGRLRDRYDSARKVTLRNDGNSFMPESPHARPANKYQLVFADDSPDFCTPNSKTGALGTQGRECNVTSSGSDRCDRLCCNRGHTRRIVEEQTNCKCVFKWCCEVTCEKCLEHRAVNTCL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::: . : . *. :::**. :*:*:* * *: :::*: :. :: *: * .**.***:.**: :****: : : ::* :* ***.** *:****. :***:**: * * :*.* . :. . . . .. . ******.*:*:** .:** *:* :::: :.*: :*:.:***:***:*:: * ***********::::** *:* **:*. :* : :. * :* ***::::. * . *::: :***** .* ::*: ** ** ** : .. . ** ***..*. *: : ** * *:*** * *. * :: :. **", "identical_positions": 125, "similar_positions": 116, "identity": "29.34%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111115-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P98164-1", "uniprot_id": "LRP2_HUMAN", "id": "P98164-1", "name": "Low-density lipoprotein receptor-related protein 2", "aln": "---------------------MDRGPAAVACTLLLALVAC---------------LAPASGQECDSA------HFRCGSGHCIPADWRCDGTKDCSDDADEIG---------------------CAVVT---------------------------CQQGYFKCQSEGQCIPNSWVCDQDQDCDDGSDERQDCSQSTCSSHQITC-----SNGQCIPSEYRCDHVRDCPDGADENDCQYPTCEQLTCDN--------------GACYNTSQKCDWKVDCRDSSDEINCT-EICLHNEFSCGNGE-CIPRAYVCDHDNDCQDGSDEHACNYPTCGGYQFTCPSGRCIYQNWVCDGEDDCKDNGDEDGCESGPHDVHKCSPREWSCPESGRCISIYKVCDGILDCPGREDENNTSTGKYCSMTLCSALNCQYQCHETPYGGACFCPPGYIINHNDSRTCVEFDDCQIWGICDQKCESRPGRHLCHCEEGYILERGQYCKANDSFGEASIIFSNGRDLLIGDIHGRSFRILVESQNRGVAVGVAFHYHLQRVFWTDTVQNKVFSVDINGLNI----QEVLNVSVETPENLAVDWVNNKIYLVETKVNRIDMVNLDGSYRVTLITENLGHPRGIAVDPTVGYLFFSDWESLSGEPKLERAFMDGSNRKDLVKTKLGWPAGVTLDMISKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLFEGQVFFTDWTKMAVLKANKFTE-TNPQVYYQASLR--PYGVTVYHSLRQPYATNPCKDNNGGCEQVCVLSHRTDN-DGLGFRCKCTFGFQLDTDERHCIAVQNFLIFSSQVAIRGIPFTLSTQ--EDVMVPVSGNPSFFVG--IDFDAQDSTIFFSDMSKHMIFKQKIDGTGREILAANRVENVESLAFDWISKNLYWTDSHYKSISVMRLADKT-RRTVVQYLNNPRSVVVHPFAGYLFFTDWFRPAKIMRAWSDGSHLLPVINTTLGWPNGLAIDWAASRLYWVDAYFDKIEHSTFDGLDRRRLGHIEQMTHPFGLAIFGEHLFFTDWRLGAIIRVRKADGG--EMTVIRSGIAYILHLKSYDVNIQTGSNACNQPTHPNGDCSHFCFPVPN------------------FQRVCGCPYGMRLASNHLTCEGDPTNEPPTEQCG-LFSFPCKNGRCVPNYYLCDGVDDCHDNSDEQLCGTLNNTCSSSAFTCGHG-ECIPAHWRCDKRNDCVDGSDEHNCPTHAPAS-CLDTQYTCDNHQCISKNWVCDTDNDCGDGSDEKNCNSTET-CQPSQFNCP-NHRCIDLSFVCDGDKDCVDGSDEVGC-VLNCTASQFKCASGDKCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSD-EFQCQEDGICIPNFWECDGHPDCLYGSDEHNACVPKTCPSSYFHCDNGNCIHRAWLCDRDNDCGDMSDE---KDCPTQPFRCPSWQWQCL-GHNICVNLSVVCDGIFDCPNGTDESPLCNGNSCSDFNGGCTHECVQEPFGAKCLCPLGFLLANDSKTCEDIDECDILGSCSQHCYNMRGSFRCSCDTGYMLESDGRTCKVTASESLLLLVASQNKIIADSVTSQVHNIYSLVENGSYIVAVDFDSISGRIFWSDATQGKTWSAFQNGTDRRVVFDSSIILTETIAIDWVGRNLYWTDYALETIEVSKIDGSHRTVLISKNLTNPRGLALDPRMNEHLLFWSDWGHHPRIERASMDGSMRTVIVQDKIFWPCGLTIDYPNRLLYFMDSYLDYMDFCDYNGHHRRQVIASDLIIRHPYALTLFEDSVYWTDRATRRVMRANKWHGGNQSVVMYNIQWPLGIVAVHPSKQPNSVNPCAFSRCSHLCLLSSQGPHFYSCVCPSGWSLSPDLLNCLRDDQPFLITVRQHIIFGISLNPEVKSNDAMVPIAGIQNGLDVEFDDAEQYIYWVENPGE------IHRVKTDGTNRTVFASIS--MVGPSMNLALDWISRNLYSTNPRTQSIEVLTLHGDIRYRKTLIANDGTALGVGFPIGITVDPARGKLYWSDQGTDSGVPAKIASANMDGTSVKTLFTGNLEHLECVTLDIEEQKLYWAVTGRGVIERGNVDGTDRMILVHQLSHPWG----IAVHDSFLYYTDEQYEVIERVDKATGANKIVLRDNVPNLRGLQVYHRRNAAESSNGCSNNMNACQQICLPVPGGLFSCACATGFKLNPDNRSCSPYNSFIVVSMLSAIRGFSLELSDHSETMVPVAGQGRNALH-VDVDVSSGFIYWCDFSSSVASDNAIRRIKPDGSSLMNIVTHGIGENGVRGIAVDWVAGNLYFTNAFVSETLIEVLRINTTYRRVLLKVTVDMPRHIVVDPKNRYLFWADYGQRPKIERSFLDCTNRTVLVSEGIVTPRGLAVDRSDGYVYWVDDSLDIIARIRINGENSEVIRYGSRYPTPYGITVFENSIIWVDRNLKKIFQASKEPENTEPPTVIRDNINWLRDVTIFDKQVQPRSPAEVNNNPCLEN-NGGCSHLCFALP---------GLHTPKCDCAFGTLQSDGKNCAISTENFLIFALSNSLRSLHLDPENHSPPFQTINVERTVMSLDYDSVSDRIYFTQNLASGVGQISYATLSSGIHTPTVIASGIGTADGIAFDWITRRIYYSDYLNQMINSMAEDGSNRTVIARVPKPRAIVLDPCQGYLYWADWD---THAKIERATLGGNFRVPIVNSSLVMPSGLTLDYEEDLLYWVDASLQRIERSTLTGVDREVIVNAAVHAFGLTLYGQYIYWTDLYTQRIYRANKYDGSGQIAMTTNLLSQPRGINTVVKNQKQQCNNPCEQFNGGCSHICAPGPNGAECQCPHEGNWYLANNRKHCIVDNGERCGASSFTCSNGRCISEEWKCDNDNDCGDGSDEMESVCALHTCSPTAFTCANGRCVQYSYRCDYYNDCGDGSDEAGCLFRDCNATTEFMCNNRRCIPREFICNGVDNCHDNNTSDE--KNCPD-RTCQSGYTKCHNSNICIPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCAS-GRCIPQHWYCDQETDCFDASDEPA-SCGHSERTCLADEFKCDGGRCIPSEWICDGDNDCGDMSDEDKRHQCQNQNCSDS-EFLCVNDRPPD-RRCIPQSWVCDGDVDCTDGYDE---NQNCT-RRTCSENEFTCGYGLCIPKIFRCDRHNDCGDYSDER---GCLYQTCQQNQFTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPEPTCPPHEFKCDNGRCIEMMKLCNHLDDCLDNSDE-KGCGINECHDPSISGCDHNCTDTLTSFYCSCRPGYKLMSDKRTCVDIDECTEMPFVCSQKCENVIGSYICKCAPG-YLREPDGKTCRQNSNIEPYLIFSNRYYLRNLTIDGYFYSLILEGLDNVVALDFDRVEKRLYWIDTQRQVIERMFLNKTN------KETIINHRLPAAESLAVDWVSRKLYWLDARLDGLFVSDLNGGHRRMLAQHCVDANNTFCFDNPRGLALHPQYGYLYWADWGHRAYIGRVGMDGTNKSVIIST--KLEWPNGITIDYTNDLLYWADAHLGYIEYSDLEGHHRHTVYDG-ALPHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSNRQTLVNTTHRPFDIHVYHPYRQPIVSNPCGTNNGGCSHLCLIKP---------------GGKGFTCECPDDFRTLQLSGSTYCMPMCSSTQFLCAN-NEKCIPIWWKCDGQKDCSDGSDELALCPQRFCRLGQFQCSDGNCTSPQTLCNAHQNCPDGSDEDRLLCENHHCDSNEWQCAN-KRCIPESWQCDTFNDCEDNSDEDSSHCASRTCRPG-QFRCANGRCIPQAWKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCEERTCHPVGDFRCKNHHCIPLRWQCDGQNDCGDNSDEENCAPR----ECTESEFRCVNQQCIPSRWICDHYNDCGDNSDERDCEMRTCHPEYFQCTSGHCVHSELKCDGSADCLDASDEADCPTRFPDGAYCQATMFECKNHVCIPPYWKCDGDDDCGDGSDEELHLCLDVPCNSPNRFRCDNNRCIYSHEVCNGVDDCGDGTDETEEHCRKPTPKPCTEY-EYKCGNGHCIPHDNVCDDADDCGDWSDELGCNKGKERTCAEN-ICEQNCTQLNEGGFICSCTAGFETNVFDRTSCLDINECEQFG-TCPQHCRNTKGSYECVCADGFTSMSDRPGKRCAAEGSSPLLLLPDNVRIRKYNLSSERFSEYLQDEEYIQAVDYDWDPKDIGLSVVYYTVRGEGSRFGAIKRAYIPNFESGRNNLVQEVDLKLKYVMQPDGIAVDWVGRHIYWSDVKNK------RIEVAKLDGRYRKWLISTDLDQPAAIAVNPKLGLMFWTDWGKEPKIESAWMNGEDRNILVFEDLGWPTGLSIDYLNNDRIYWSDFKEDVIETIKYDGTDRR-VIAKE-AMNPYSLDIFEDQLYWISKEKGEVWKQNKFGQGKKEKTLVVNPWLTQVRIFHQLRYN-KSVPNLCK-QICSHLCLLRPGGYSCACPQGS----SFIEGSTTECDAAIELPINLPPPCRCMHGGNCYFDETDLPKCKCPSGYTGKYCEMAFSKGISPGTTAVAVLLTILLIVVIGALAIAGFFHYRRTGSLLPALPKLPSLSSLVKPSENGNGVTFRSGADLNMDIGVSGFGPETAIDRSMAMSEDFVMEMGKQPIIFENPMYSARDSAVKVVQPIQ-------VTVSENVDNKNYGSPINPSEIVPETNPTSPAADGTQVTKWNLFKRKSKQTTNFENPIYAQMENEQKESVAATPPPSPSLPAKPKPPSRRDPTPTYSATEDTFKDTANLVKEDSEV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A2ARV4-1", "uniprot_id": "LRP2_MOUSE", "id": "A2ARV4-1", "name": "Low-density lipoprotein receptor-related protein 2", "aln": "---------------------MERGAAAAAWMLLLAIAAC---------------LAPVSGQECGSG------NFRCDNGYCIPASWRCDGTRDCLDDTDEIG---------------------CPPRS---------------------------CGSGFFLCPAEGTCIPSSWVCDQDKDCSDGADEQQNCPGTTCSSQQLTC-----SNGQCVPIEYRCDHVSDCPDGSDERNCYYPTCDQLTCAN--------------GACYNTSQKCDHKVDCRDSSDEANCT-TLCSQKEFQCGSGE-CILRAYVCDHDNDCEDNSDEHNCNYDTCGGHQFTCSNGQCINQNWVCDGDDDCQDSGDEDGCESN-QRHHTCYPREWACPGSGRCISMDKVCDGVPDCPEGEDENNATSGRYCGTGLCSILNCEYQCHQTPYGGECFCPPGHIINSNDSRTCIDFDDCQIWGICDQKCESRQGRHQCLCEEGYILERGQHCKSNDSFSAASIIFSNGRDLLVGDLHGRNFRILAESKNRGIVMGVDFHYQKHRVFWTDPMQAKVFSTDINGLNT----QEILNVSIDAPENLAVDWINNKLYLVETRVNRIDVVNLEGNQRVTLITENLGHPRGIALDPTVGYLFFSDWGSLSGQPKVERAFMDGSNRKDLVTTKLGWPAGITLDLVSKRVYWVDSRYDYIETVTYDGIQRKTVARGGSLVPHPFGISLFEEHVFFTDWTKMAVMKANKFTD-TNPQVYHQSSLT--PFGVTVYHALRQPNATNPCGNNNGGCAQICVLSHRTDN-GGLGYRCKCEFGFELDADEHHCVAVKNFLLFSSQTAVRGIPFTLSTQ--EDVMVPVTGSPSFFVG--IDFDAQHSTIFYSDLSKNIIYQQKIDGTGKEVITANRLQNVECLSFDWISRNLYWTDGGSKSVTVMKLADKS-RRQIISNLNNPRSIVVHPAAGYMFLSDWFRPAKIMRAWSDGSHLMPIVNTSLGWPNGLAIDWSTSRLYWVDAFFDKIEHSNLDGLDRKRLGHVDQMTHPFGLTVFKDNVFLTDWRLGAIIRVRKSDGG--DMTVVRRGISSIMHVKAYDADLQTGTNYCSQTTHPNGDCSHFCFPVPN------------------FQRVCGCPYGMKLQRDQMTCEGDPAREPPTQQCG-SSSFPCNNGKCVPSIFRCDGVDDCHDNSDEHQCGALNNTCSSSAFTCVHGGQCIPGQWRCDKQNDCLDGSDEQNCPTRSPSSTCPPTSFTCDNHMCIPKEWVCDTDNDCSDGSDEKNCQASGT-CHPTQFRCP-DHRCISPLYVCDGDKDCVDGSDEAGC-VLNCTSSQFKCADGSSCINSRYRCDGVYDCKDNSDEAGCPTRPPGMCHPD-EFQCQGDGTCIPNTWECDGHPDCIQGSDEHNGCVPKTCSPSHFLCDNGNCIYNSWVCDGDNDCRDMSDE---KDCPTQPFHCPSSQWQCP-GYSICVNLSALCDGVFDCPNGTDESPLCNQDSCLHFNGGCTHRCIQGPFGATCVCPIGYQLANDTKTCEDVNECDIPGFCSQHCVNMRGSFRCACDPEYTLESDGRTCKVTASENLLLVVASRDKIIMDNITAHTHNIYSLVQDVSFVVALDFDSVTGRVFWSDLLEGKTWSAFQNGTDKRVVHDSGLSLTEMIAVDWIGRNIYWTDYTLETIEVSKIDGSHRTVLISKNVTKPRGLALDPRMGDNVMFWSDWGHHPRIERASMDGTMRTVIVQEKIYWPCGLSIDYPNRLIYFMDAYLDYIEFCDYDGQNRRQVIASDLVLHHPHALTLFEDSVFWTDRGTHQVMQANKWHGRNQSVVMYSVPQPLGIIAIHPSRQPSSPNPCASATCSHLCLLSAQEPRHYSCACPSGWNLSDDSVNCVRGDQPFLISVRENVIFGISLDPEVKSNDAMVPISGIQHGYDVEFDDSEQFIYWVENPGE------IHRVKTDGSNRTAFAPLS--LLGSSLGLALDWVSRNIYYTTPASRSIEVLTLRGDTRYGKTLITNDGTPLGVGFPVGIAVDPARGKLYWSDHGTDSGVPAKIASANMDGTSLKILFTGNMEHLEVVTLDIQEQKLYWAVTSRGVIERGNVDGTERMILVHHLAHPWG----LVVHGSFLYYSDEQYEVIERVDKSSGSNKVVFRDNIPYLRGLRVYHHRNAADSSNGCSNNPNACQQICLPVPGGMFSCACASGFKLSPDGRSCSPYNSFIVVSMLPAVRGFSLELSDHSEAMVPVAGQGRNVLH-ADVDVANGFIYWCDFSSSVRSSNGIRRIKPNGSNFTNIVTYGIGANGIRGVAVDWVAGNLYFTNAFVYETLIEVIRINTTYRRVLLKVSVDMPRHIVVDPKHRYLFWADYGQKPKIERSFLDCTNRTVLVSEGIVTPRGLAVDHDTGYIYWVDDSLDIIARIHRDGGESQVVRYGSRYPTPYGITVFGESIIWVDRNLRKVFQASKQPGNTDPPTVIRDSINLLRDVTIFDEHVQPLSPAELNNNPCLQS-NGGCSHFCFALP---------ELPTPKCGCAFGTLEDDGKNCATSREDFLIYSLNNSLRSLHFDPQDHNLPFQAISVEGMAIALDYDRRNNRIFFTQKLNPIRGQISYVNLYSGASSPTILLSNIGVTDGIAFDWINRRIYYSDFSNQTINSMAEDGSNRAVIARVSKPRAIVLDPCRGYMYWTDWG---TNAKIERATLGGNFRVPIVNTSLVWPNGLTLDLETDLLYWADASLQKIERSTLTGSNREVVISTAFHSFGLTVYGQYIYWTDFYTKKIYRANKYDGSDLIAMTTRLPTQPSGISTVVKTQQQQCSNPCDQFNGGCSHICAPGPNGAECQCPHEGSWYLANDNKYCVVDTGARCNQFQFTCLNGRCISQDWKCDNDNDCGDGSDELPTVCAFHTCRSTAFTCANGRCVPYHYRCDFYNDCGDNSDEAGCLFRSCNSTTEFTCSNGRCIPLSYVCNGINNCHDNDTSDE--KNCPP-ITCQPDFAKCQTTNICVPRAFLCDGDNDCGDGSDENPIYCASHTCRSNEFQCVSPHRCIPSYWFCDGEADCVDSSDEPD-TCGHSLNSCSANQFHCDNGRCISSSWVCDGDNDCGDMSDEDQRHHCELQNCSST-EFTCINSRPPN-RRCIPQHWVCDGDADCADALDE---LQNCT-MRACSTGEFSCANGRCIRQSFRCDRRNDCGDYSDER---GCSYPPCRDDQFTCQNGQCITKLYVCDEDNDCGDGSDEQEHLCHTPEPTCPPHQFRCDNGHCIEMGTVCNHVDDCSDNSDE-KGCGINECQDSSISHCDHNCTDTITSFYCSCLPGYKLMSDKRTCVDIDECKETPQLCSQKCENVIGSYICKCAPG-YIREPDGKSCRQNSNIEPYLVFSNRYYIRNLTIDGTSYSLILQGLGNVVALDFDRVEERLYWIDAEKQIIERMFLNKTN------QETIISHRLRRAESLAVDWVSRKLYWLDAILDCLFVSDLEGRQRKMLAQHCVDANNTFCFENPRGIVLHPQRGYVYWADWGDHAYIARIGMDGTNKTVIIST--KIEWPNAITIDYTNDLLYWADAHLGYIEFSDLEGHHRHTVYDG-TLPHPFALTIFEDTVFWTDWNTRTVEKGNKYDGSGRVVLVNTTHKPFDIHVLHPYRQPIMSNPCATNNGGCSHLCLIKA---------------GGRGFTCECPDDFQTVQLRDRTLCMPMCSSTQFLCGN-NEKCIPIWWKCDGQKDCSDGSDESDLCPHRFCRLGQFQCRDGNCTSPQALCNARQDCADGSDEDRVLCEHHRCEANEWQCAN-KRCIPEYWQCDSVDDCLDNSDEDPSHCASRTCRPG-QFKCNNGRCIPQSWKCDVDNDCGDYSDEPIHECMTAAYNCDNHTEFSCKTNYRCIPQWAVCNGFDDCRDNSDEQGCESVPCHPSGDFRCGNHHCIPLRWKCDGIDDCGDNSDEESCVPR----ECTESEFRCADQQCIPSRWVCDQENDCGDNSDERDCEMKTCHPEHFQCTSGHCVPKALACDGRADCLDASDESACPTRFPNGTYCPAAMFECKNHVCIQSFWICDGENDCVDGSDEEIHLCFNVPCESPQRFRCDNSRCIYGHQLCNGVDDCGDGSDEKEEHCRKPTHKPCTDT-EYKCSNGNCVSQHYVCDNVDDCGDLSDETGCNLGENRTCAEK-ICEQNCTQLSNGGFICSCRPGFKPSTLDKNSCQDINECEEFG-ICPQSCRNSKGSYECFCVDGFKSMSTHYGERCAADGSPPLLLLPENVRIRKYNISSEKFSEYLEEEEHIQAIDYDWDPEGIGLSVVYYTVLSQGSQFGAIKRAYLPDFESGSNNPVREVDLGLKYLMQPDGLAVDWVGRHIYWSDAKSQ------RIEVATLDGRYRKWLITTQLDQPAAIAVNPKLGLMFWTDQGKQPKIESAWMNGEHRSVLASANLGWPNGLSIDYLNGDRIYWSDSKEDVIESIKYDGTDRR-LIIND-AMKPFSLDIFEDQLYWVAKEKGEVWRQNKFGKGNKEKLLVVNPWLTQVRIFHQLRYN-QSVSNPCK-QVCSHLCLLRPGGYSCACPQGS----DFVTGSTVECDAASELPITMPSPCRCMHGGSCYFDENDLPKCKCSSGYSGEYCEIGLSRGIPPG-TTMALLLTFAMVIIVGALVLVGFFHYRKTGSLLPSLPKLPSLSSLAKPSENGNGVTFRSGADVNMDIGVSPFGPETIIDRSMAMNEQFVMEVGKQPVIFENPMYAAKDSTSKVGLAVQGPSVSSQVTVPENVENQNYGRSIDPSEIVPEPKPASPGADETQGTKWNIFKRKPKQTTNFENPIYAEMDTEQKEAVAVAPPPSPSLPAK---ASKRSSTPGYTATEDTFKDTANLVKEDSDV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9Q8X3-1", "uniprot_id": "A0A8M9Q8X3_DANRE", "id": "A0A8M9Q8X3-1", "name": "Low-density lipoprotein receptor-related protein 2", "aln": "---------------------MDQLGLYILAVLFLIHGPY---------------IVQG---QCMSG------EFQCSNGQCINQDWKCDGTKDCTDNSDELN---------------------CPLPT---------------------------CSSQEFKCLTGGECIPLEFVCDGEADCADGSDEQRTCSGQTCSPDQFTC-----REGQCIPKQYNCDHVPDCVDNSDENNCNYPACTEKTCAN--------------GACYNNAQHCNGILDCRDGSDESNCT-RHCQSHQFECANGF-CIPMPFVCDHWDDCGDNSDEQNCEYRTCSGSEFACSNGRCMPQQWVCDGINDCGDFSDENGCDPG---IRDCYPGEWPCPGSSLCVPVNKVCDEHPDCPGGTDESNATAHLTCDLHQCSALSCEYRCHPTPQGGACYCPDGFTVAN-DSRTCVDYDDCKIWGICDHFCEDRPGTHHCSCADGYFLEQGHVCKANISGGLPQLIFTDGRDIKMADIHGRFIRLLVQSDGKGYAVGVGYNWHTQRVFWTDTSSQKVFSINFDGSDK----MEVLSEAVHNAQNVAVDWINFKLYLVEERVERIEACDYDGGNRVTLIAENLVTPHGLALDPTVGYMFFTDSGDNTDDVKLERAFMDGSNRFDLVRTRLGSPTGITLDLVTKRVYWTDSHFNLVETVTYSGLDRKTVLNGGHQVPHPFGISVFENHAFFTDWVKMGVIRTNRFNG-SDPTFLYRSTNR--PGQIVVSHPALQPFVINPCGRHNGGCQQICLLSHRTDN-DGLGYRCMCRLGYDLQDDRHSCFKIKDYLLVAYAQAVRGIPLNVSSQ--EDVTLPLSGLADTFSGSGVEYDASVESVFYNDRMRQLIYKSNINGTSHKVLTGYRVGAVESMAYDWTSKILFWTSSTYRSVCAFKVTDGS-RQDIVKNLIYPRGIAVHPSAGYLFWSDWYRPAVITRAYTDGSNAVPLINTTLGWPNGLAVDYMMDRLYWVDAQLDRIEHVSIDGFDRQAFSSIGQITHPFSLTIHTDHLFVSDWRTNSVFRMRKRDGG--DNIMLRKGISGIMNIKAYSADLQDLFKSRCN-MIPNGRCSHFCFPTPA------------------SSRVCGCPFGMKLQENQRDCVKDDSEPPPDDNCG-DYAFPCDGGRCVPNTYRCDGVNDCVDKTDEVNCTLPGATCSPYAFTCGNK-HCIPARWRCDGHDDCGDGSDETNCPTRGPTT-CSSSQFACTNGNCIPKTWVCDAFNDCGDGSDERHCNSSITTCQPGFFLCP-DHRCIYNSYVCDGDQDCLDGSDEKDC-VYTCGTYEFACASGDQCVSQSYRCDGVYDCKDHSDESGCPTRRPGLCHDN-EFQCQVDGFCIPKEWECDGHPDCVDGSDEHNGCPPRTCSSVQFQCANGNCVSKNWVCDGENDCRDMSDE---TNCPTPPFSCPSGQWLCP-TDQVCIMNAQVCDGQRDCPNGADESPICNEDDCKVNNGGCSHGCIQGPFGAQCTCDPGFQLLNDSKTCDDINECLIPGFCSQTCFNERGSFRCYCEDGYQLEPDGRTCRATSPGNALLLVARRSQIIGNRINFWPP-IISPIVSGMSIVAVDFDNVNKRVYWGDSSDKMIYSSFQNGTDKKQVFSSGLMVPESIAVDWVGRNIYWTDSVMQNIEVATLDGHFRKILITKNVTSPRGLVLDPRNHTNLMFWSDWGQNPRIEQASMDGLGRRAIVTSKVYWPNGLTLDYTTRRVYFVDAYLKYIDYCDYDGKNRHQVFASDIVLQQPHGITIFEDNIFWSDSYTSQIMRTNKFHGGNITTLLTGVYQCMGIVMDHPIKQPIAFNPCENNPCSQLCLLSTLRPRYYRCDCQSGWILASDGRTCTKDETPFLMVVRDTVIMGIPLNPNDTSNNAMAPISGITQGRDIDFDDREQFVYWVQGTGA------IYRSKTDGANRTQFAPAA--IIGSPSGLAFDWITRIMYYTNPTIKAIEVIRVDGSQHYRKTIITNTGKPEGAGQPIGIALDPARGKLFWTDRGSDSGVPPKISSADMDGGNVKNLYTGNLVKVEFIAADIEARKIYWGVHQTGMIECGTMDGASRVTIVSGLSHPWG----ITVYQNYLYYTDLDFEVIERVDKNTGADMVVMRSSMAGLRSVKVHARDNSAGTTNACSTNNGGCPHLCLPKPQGQKTCACTTGFIPSQDGSHCEQYDSYAIVSSSKFIRGFHINSSDHSEAMVPVGANTYSIIDKLDMHIASGFLYWTDN-STYSSYRGIYRTKTDGSRYSTVISQ-LGNGRIQGLAVDWIAGNLYFTNKFTTQTYIEVLRLNTSIQLILLKSSADRPQDLAVSPKLRLLFWTDAGQSPKIESALLDGTNRTVLASESLSSPRGLTIDYTNDFLYWVDDTLDMISRMAPDGSQREIVRFGSRYPAPYSVAIFGEYMLWVDRKLGKLFQASKVPGNTDTPEVIRDGIDDLTDVAVFDSHVQPTSANLVGFNPCHDD-NGRCQQFCFALP---------DQQEPKCACAHGSLLSNGVSCGFGLDEYLIFTTDYSVSSMRLDPEDHSVPFPTFNMGYGVLAIEFDFQDKRVFFTQYVGLGRSKIGYIITTSSTSPPVTIASDLDDPEGLAYDWVHKRLYFTDYYNRSVQSMGIDGQNRSLIAHGDRPRAIVVDPCYGYLYWTDWG---SPAKIERATLGGNFRIPVINTSLSQPNALSLDYEERLLYWADSTLDKIERSSLTGENREVILTQTQYPFALTVFQQDIYWTDWNTRIVYRASKDDGSGLTIMATDLQYRPNDIHVFSASRQESCSSPCQLFNGGCSHVCVPGPAGPECQCPSTGNWYLANEGKDCIPDNGQRCHADQFTCLDGRCLSQNFKCDGYRDCLDGSDELERVCAFHTCSPTEFTCDNGGCVPLYYVCDYTNDCGDNSDEHGCPFPTCNPSTEFTCANGRCISAAYVCDGINDCRDNGTTDE--VNCPD-RTCAPGLVKCDTTNICIPSSSLCDGHNNCGDNSDENPLFCAGRTCSADEFRCDS-GKCIPQFWVCDRISDCLDGTDEPP-TCEDHIYTCSPQQFNCANGNCIQQSWVCDGNNDCGDNSDEAQELQCGSRTCNPG-DFTCPSWYPGS-PRCIPLSYVCDGEKDCVDAADE---LHNCP-NRTCHLNEFACANGRCILLPFHCDRVNDCGDGSDET---NCIYNTCSSREFTCQNGVCIPSTYVCDGYIDCQDGSDELEGLCRTPEPTCAPGDFMCNSGECIDIHKVCNQQRDCSDNSDE-KGCGINECTNPAIHQCAHNCIDTQTGYYCSCREGYRLMPDGKACEDIDECKEVPGVCSQVCENAVGSFYCKCAPG-YLREPDGRTCRQNSGIAPYLLYSNRYYIRNLTAVGSSMSVVLQGLTNVVALDFDTTEKRLYWVDVGTLRIERINLDGTG------REVIMQNDLGGAEGLAVDWVGRKLYWADATMKAIHVSELDGRYRKKLLKDCVDTNSTYCFASPQAVAVNPKYGWLYWTDWGRKAFIGRAGMDGTQASALITT--KLVWPHALTIDYTNNKIFFADAHLNFLDYADMDGQNRHRAITG-SLPHAYALTLFEDLVYWTDWNTHTIERAHKYTGANRVVMGNNTHRPNDIHIYHPYRQPHSENPCNDHYLTCSHLCLIGP---------------GGTEARCECPDHFIGLAIGFKIQCVADCSSTQFRCGD-NEKCIPIWWKCDGQSDCGDGSDEPQTCPPHYCKTGQFQCQDGNCTNPFFLCDGHKDCFDGSDEDAALCSDHRCTENQFQCKN-KHCIPITWHCDGVVDCSDGSDEETDSCIDKTCKPG-QFQCKKGGCIPQSYVCDAQNDCGDNSDEPYEVCMGPDYKCDPDTEFPCKGNYRCIPLWAVCDGTNDCLDNSDENTCHELTCDPLGDFRCDNHRCVPIRWRCDGSNDCGDGSDERNCEPR----PCSESEYRCDNQQCIPGAWVCDHDNDCGDNSDERDCELRTCRPGTFQCTSGHCIPEALKCNGYADCLDFSDESTCPTRYPGGRWCPAHQFQCNNKLCVNQQWVCDGFNDCGDRSDEQLSLCWNITCEMPTKFRCDNGYCIYSGLMCNQKDDCGDGSDEKEDQCQEPTLAPCTPN-EFKCSNGHCVPLPYVCDHNNNCGDLTDELGCNFGHDRNCDEK-LCKHECTNLNGTGFICSCRPGYAVDPDNTFLCNDIDECLEYG-TCPQACMNTKGSYHCDCAQGYRKAGT--GNQCEAEGPGPLLLLPENIRIRRYNLQTEEYHDFLQEEERIVALDYDWDHNNTGFSVVYFTVEGRGALPGAIKRAFLPDVDDHNNNIAAAVELDIKYITKPYGIAVDWVGRNLYWADAQLK------RLEVAMLDGRYRKHLIKTDLEAPNSVALNPRLGMLYWIDNGNTPRIECSWLDGQERKVLVNNGLGWPTGLSIDFTNGDRIYWSDAKESRIESILPDGQNRKTSVFID-VRNPFSVNVFEDHVYWSTQEKGEVFRQDKFGKGTKTRLLVTGPWLTQINIYQQQKYNSIALKNPCK-GTCSHLCLLRPGGYTCACPEGT----SFFPGSSTACDAGIDPEPTMPPPCQCKNGGTCYFDDN-KALCICPSEWKGDFCETSVYGVVTTS-VAIALGVTAVVALFLGCLIYS-AHKKENIKNRLNNINLPVNVSNFMPTFWRGNSERFSNSPESENDS--------NSLPKEESSTSVEVEKIGRN---FENPAYADDTQSCPAASTAT------ATSVINGPAKESVENPLYAAEISVVTQPHDAATPVKADATPVNTESQKADTSKLQS--EVDIDNVFDNPLYMDEPHIQ------------------SNGESTI-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JTM7-1", "uniprot_id": "A8JTM7_DROME", "id": "A8JTM7-1", "name": "", "aln": "MNPTPVGIGFGFGRKPPSKARMRSRWRPPSATTLLTHDPANGDSHTAADPLQVTDAAPSGPPSSSSSSPIGDRHSQHHSSSAIDRRLQQQQHHQSPQHHRQRGQLTTLALLLLALVAISNLETLLAVRTEGPRNRHGSPGGSLASTGGSSSGINTECPTDSFRCNN-GKCISHHWVCNYQKDCDDGEDEMQSCPPPECETPQLNCGQYTFNKTYCIPPHYRCDMIEDCEDKSDEAQCTYRKCQHTDLFCNTPTGAPAEGARLTGPCVPKEKRCDGYLDCRTGRDEVGCSGVACRLDQFRCANGLKCIDAALKCNHRDDCGDNSDEQGCNFPPCHHAQFRCTNALCIPYNFHCDGYHDCADKSDEANCTAIACPDNKHLCPRGGASGTPKCILKSQLCDGKRDCEDGSDEETN-----CSIASCPALSCEFKCGPSLTGGVCYCKPGQSLAP-DNRTCVDLDECAEWGHCDQLCTNTLGSYTCQCAQGYTLINDSKCIAPDAN-NLQLIFAHDRAIMRMLPHGSEPKILANAT---AAAGVTFHYARNTLYWSDIKTRKVQSLPLDAQNKAVSPFDQTLPGTWAPVALAVDWVGDKIYVADLVGQKIDVFELSGQWHAVVLGSNLTSPADLALDPTAGLMFVADGG------QVLRAHMDGTHARSIVSEAAYKASGVTVDIISKRVFWCDSLLDYIESVDYEGAHRVMVLRG-QQVPSPSRLALFENRIYWTDATKQGIMSVDKFEGPTSIQVTYKAKDIREPKGIIAVHALSQPRVSNPCGNNNGGCNHMCIVTAVKGAPTGLGFRCACSTGYQLETDLKLCKPVSEFLMYSQQRFIKGKVLEPVIEGFSDAIMPVVSRRARFVG--LDFDARDEFIYYSDVLQDVIYRVHRNGTGREIVLASQNEGVEGLAVDWASKNLYYIDSRKGTLNVLSTRNVTHRRTLLKNLKRPRAIVVHPNRGFIFFSEWDRPANITRANTDGSGLLVFKNVTLGWPNGLSIDFKEDRVYWCDALLDHVQHANLDGTDIKTVNSR-LVRHPFSIVIHNDWMYITDWRLDAIIRLHKLTGEQEEMMVREPQTNRLYGVKVYSHEVQR-IADTQPCHRNNGGCQKICFAVPIGASNGTDGVTTSSPSFGRLQSRCSCPYGERLADDQVSCIPDPSAEPPVQPCPNSWDFTCNNQRCIPKSWLCDGDDDCLDNSDEEQN-CTKPTCGSNEFQCRSG-RCIPQNFRCDQENDCGDNSDEQECGN----VTCGTSQFACANGRCIPNMWKCDSENDCGDSSDEGDFCAEKT-CAYFQFTCPRTGHCIPQSWVCDGDDDCFDKQDEKDCPPISCLANQFKCADLRQCVEESYKCDGIPDCNDGSDEVGCPSMGPNQCNLEKHFRCKSTGFCIPIAWHCDGSNDCSDHSDEQD-CGQITCAQNFFKCNNTNCVFKAYICDGKDDCGDNSDEGAEHACVPPPFKCPHGQWQCPGVSERCVNITSVCDDTPDCPNGSDEGEGCDLAECEHQAGQCSSFCQKTPNGALCVCPPGSEIGEDGYTCIDSNECDPPGLCSQQCTNTKGSYFCSCTDGYVLEPNKHTCKAVNHTAAFLIISNRHSILVADLKEQGLERVPIIVEN--VVATASNMHTGTIFWSD-MKLKKISRLDRGMEPQEIINTGLDLVEGLAYDWIAQNLYWLDSKLNTIEVSAENGSNRLVLVRENITQPRGMCIDPSPGARWIFWTDWGENPRVERIGMDGTMRKTIINTKIYWPNGLTLDIATKRVYFADSKLDFIDFCYYNGTGRQQVLASSHYLLHPHSLSLFEDTLYWTDRQLNRVLSANKFRGKNQTVVSHLISQPLSIHVHHASLQPMTPNPCAGSRCQHLCLLSPSAPEGYSCKCRPGFKLLSEGR-CIEEENPFLMVVKGTQIVDLPLNGGDARAGALAPVIGIESSTGLDFDRKGETLYWVQGREDDDENCTIYTTPYGGGNKTLFLGIENGIVGAPYTIAFDWLGRNLYIGNRVASNIEAVRVDGKQKYRTIILANDGYPNSVSRPKQIALDPTEGKLFWIDEG-VLEVPIKIGRVDMNGQNPIVVFQ-EFAHPESLAVDTEKKMVYYSASNPAVIGVMDYNGDDHTLILMKDSHPMAKPRSLGILDHRLYYLDPLYERIVRIDLPHGDNPKTIVDNESDLRSMMIYKKR--ALMQHPCQTNNGGCKHLCIPGPGATRTCACGIGYR-KENEINCVAYKIFAVVSQLDMIRGYSLS--DSSEAMVPISGPGHHILH-VDVMYREQWIYWAEYNRGYWN--GIFRSRPNGTDLQHVVKDGIGSNGIRGLTIDWVAGNMYFTNVYPHENYVEVCWLDGSNRKVLVKTTTDAPRELAVNPIKRLLYWIDYGQHPRIGKALLDGSKWTPLVTSGISLPRDLTIDMQTHDIYWVDSKLDTIQKISYNGANRKIIRR--DLPNPMGIAVYLNDVYWVDRNLMTVFKASKHSAN-ETATSVRTNLEKLRDIAIYNINNQPQD----DTNPCAHLGNGGCDQLCFSFPPDGGASGTSGGRNFRCECATGKLSADERKCEVVN-EYLVFATRTEIRAVNLDPHSTEVPFTPLTNLTNVVGLDFDFAHNRMLYTQIRPWAKIAYTKANKPGHDDITVVLNKGIN-PEGIAYDWTQQKIYWTDSSNNSIYAMNLDGSELVMIARVERPRAIVLDPCNGTLFFTDWGRFGTSGKIFRTTMAGSLKRAIVDKDLSQPSGLAIDYDERRLYWTDAVREKIERSDLDGQNRELLVAATIYPFAITVFRNYIYWTDLQLRGVYRAEKHTGANMVEMVKRLEDSPRDIRIYSSDRQKCNVNPCRINNGGCAQSCHPAPNG-KAECKCDDSTKVVNEGRMCAPRN-NTCEASKFYCKNGRCISRMWSCDGDDDCGDNSDEDPNYCAYHSCSPNEFRCNNGRCIFKSWKCDHENDCKDGSDELGCVYPPCVDG-EFTCANGRCIPQAQVCNGVNDCKDNATSDETHERCPMNTTCPANHLKCEKTNICVEPYWLCDGDNDCGDNSDEDPLHCGQRTCPTNSFRCPN-HRCIPATWYCDGDDDCGDGADEPPDYCKSEGRTCFGDLFTCDNGNCIPRIYICDGDNDCLDNSDEDNRHQCNDRKCDEETEFTCVENKSWQRAQCIPKKWICDGDPDCVDGADENTTLHNCATQQPCGEDMFTCGNGRCINKGWICDHDNDCGDGTDEGKFCNSKYKTCSAQEFTCQNFKCIRNQSRCDGEDDCGDHSDEVG--CAKENITCPQGQFACTNGQCIDYNLVCNKYPDCADESDEPAHCNVDECAKVEINQCGHKCVDTLTGYYCDCNEGYKLLADGKACADVDECLEQPGACSQHCSNTPGGFYCKCDETYYERQNDEHTCKRKDKIPPWLIFTNKYYVRNMSVDGHQYNLMHQDLMNVVALDFDIREEYMYFCDVTAKTIFRAKYGEADDEMPPEREAVIRHDSHGLEGIAIDWVGRKLYWLDRHSKNLDVSELDGSKRKTLRSGVVDP---------RAIVVHPGIGYLYFTSWHLQAYIAKMGMDGSNFSRILNWNDGIAWPNALSIDYFTDRIYWADAHLDYIAYADLEGRHRHTVLSGSKVPHVFALSLFDDYIYWSDWNLKAIVRANKFHGANYTVLRNTTHRPYDLHINHPLRQLPYTNPCGTNNGGCSHLCLIAPPPESTYLNIEGYIEEGAPIFKCACPNQFY--LARDMKTCVANCTAGQHLCGGRDEKCIPWFWKCDGEKDCKDGSDEPATCAPRHCRAGTFQCKNTNCTPSATICDGVDDCGDRSDEQ---NCDLPCPLSDFKCKSSGRCILDSWRCDGDADCKDGSDEDPAVCFKRTCDPKTEFSCKNGRCIPQLWMCDFDNDCGDDSDEPAYMCRQRNCTTG-WQRCPGQSNYRCIPKWLFCDGKDDCRDNSDELPENCPKCNPETDFKCGNNRCIPKQWMCDFADDCGDASDENEAVCKGRYRECSESEFRCGNGKCISSRWQCDHEDDCGDNSDEMHCEGYQCKNGTFQCASGHCIASYFRCDGDRDCRDMSDEVGCPPRFPGGRYCPESRFQCNNNLCVSLSDLCDGTDDCGDGSDEDPSVCSDFNCDTLRRFQCSNERCVARYQICDGVDNCGDGSDENNMTLCASKQKPCDLYTQYQCANKHCIERSQVCDFSDDCGDASDELGCHHTSSCSEANRGGCQQHCHNLTDGGYICTCYPGYIIAADNKKKCSDVDECLTRQHTCSHQCHNLNGTYSCSCREGFHLTDG-ASGVCRAEKEDVILLFVNGQEIRGLNWHKSEEFAVIAAEKRIEALDYDAQQQIVFWADSYDKT---------IKRSYMVNAIDGRAKIGFAQDLNMKGGSKPTAVAVDWLASNLYWTEMDRTGSKPRGRVMVAKTDGRYRRSIVNAGLEVPTSIAVNPQLGRIYWSDAGSAPKIEVSWMDGSKRRPLITEMIRHPAGLTIDYSQDHIIYWVDTKLNAIESMRADGSRRKAIVRGDQLRHPVSLDLFESNMFWMTRDTGELVRQDKFGRGVQVVLHRYIVNPSGLKVYHDKRYN-TSLPNPCDNSTCSHLCLLVPGGHRCACPDASGPPPSHRSTAEVICNAAAEHPRPAPRICPCQNGGLCKEDAQGELLCECRTQFVGEHCETSTMGAFGHGDANVTAVVVPIMVILLVMMAAAGAWYVIRKRPFGKLARMPAMTSSQSVTFRHGSNVEFNESGFPGASAP-------GAGDVAPIEGYNLQTVNANKARDFANPMYDAVQSGTTADPGMGNGSGIYDVPGEPSAKVKSMGHHAGGSFTEPASAIIAPSSITHKASPQLQLRTRELDPS---------ADTGKDTQFLVEEDKSEC-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :* . . .. *. . : .. .* : : ::. :. : . . : * * * * **. :**: : ** ** ** : *. *.. *:.* : *:* .*.** : ** * :** :* * * . *.* . ::*: :*** . ** .*: * .:* *..* ** . *:* :** *.***: *:: .* :* *... *: :: *** .** * .** .* . . . .. : *: ::** ** **.. *. *. *.*:::* : ** *:* * : *.***:: *:* ** **: * . * : * * :** * .. * : : .:**:..* : ** ::*.:: . ** ::: : ::*:* ** * ::. : : . . :****:. *:*:.: ::*: : .* :..:: .** * .:*:***.* :*.:* :: **.***:: .:* .:*:*:*:::***:* ** : :*:* *.* .* * .* :* * :::** : ::** .* .:: .::* :. . :::. * : . *. ** . *** :**** ::*::: .. ***:** * *::*: * : * :.::*: : ::* : : .*. :*: . * * :::** . :::.* :.:*:: : :**.:::: . : ** :: ** *: *:: .. :: .: : : *: ::. * **.:.*** *::* ::* *** * ** :*** : . *.:*******::*: .*:** ** :*:::* .:** * : .. : ***.:.:. : ::.:*** .:::*::* * : : . : :* *. ::* ** *.::**..* . *.**:* :* :: * * : ** : * *.*.. :*:*. : *** :** *::** **.. * * .*** .:*** .:** *.*** :* . * :.::* * **.: * **: ***.*.*** . : * * * ** :** :*****.**.* .** .* .* : :* **. .*: :***: **.* *** ***: *. *: : .*:*: * *** *.*** ** ***:: * **. * * * **: . ::** .:** * *** * . ** ** ** * . *: : :**. *****:**. *: .* * *: * : * ** * * * : :* ** * :** * *** * * :**: * * * **.: :**:.. :*::: : .*: :. . : . :** : . ::*.* . * ::.* : : : .:.: : * :* **:.:*:** * ::.***: :* * :*: :*:*.***: :** . :**:***.:**:*: .*** * .*: *::** **::* ..: :** *: *.::::* *:* *:**:**. : :*:.:::***.::*:* ::: :**::* * :.: : :.* *. ** : *** *.:*****. *. * * * .*: * : * . : ***: *: *..:.*: .*:.*: ** . .::** : :***:. *: .* *:* * ::*.. :*:**: * :* . **.: : *. :* . :::* * . ... * *::**:.***:* *.* ** **. .:*:* . :: :: : * :: * : : :*:.. .:* :* .: :: :** . : : *** * :* * *:* * : .: .. . **.: :: : * : *..* ..* ::*:* * . :*** *: . : * *. : :** :**: :. * **:***:.. :. *: . ::** : . .* * :.:*: ::. :* . ::*:::**:***:**** : :. :** :: : : :*:* :.* *:.:.*.* * *:* * ** *:* ::** :: * *.:..: **.*::* :****..** * :: :* : :::* * * .:::: : : ****:* .:*:*** . * :.. :* .:: * *::::: : ** . . *** . ** *.::**::* :* ** *.* : .* ::*::: .: ::.:**.. . ** .:. .:.:::* .*: :** . .. : ..:. .:*:*:** :::*::* *. : :* **.: :**: :*****:*** * ::::**. : .** *:*:.*.:: .:::..* *..*::* : ***.*: ::**** * * :**::: : :.*.:*:: : ***** : :***.* *:. *.. * * .* ::: .** ****:: * *.* * :.:* .. :.*: : * . * .* * :***:*. :.**. ** *.*** ** *:* .. * * ** *: : **. *** *.*** ** : * ** * * ***. :*:*:::*:** *:** .** ** .. **..:***: ****.*:***.***:* .* :** :..*:* . :*** * ** ** *.:*** * :* : * * .*.** ::***:*** * *** :. :* :.*. :* * . . . :*** ::***: **.*. ** :**. :.* . *:*. * ** : **: ***** :** .. * .* :***** ** . ** ** * *** * . : **. :* * .*.**: :**: ** *:*** *.::** . * * *:* ** *.:**.* **:*:.* ::* *:*** * * *** *.*. *.: *** * *: * ::*:::. * *:*:::*:**:**:: * .:: :.* ******** *: :*: *. * * . :. :*.:: : *.:*:***.***** * . : **:*:* *: * . **. :.:.::* *::*::.* :*:*.: ****:: : ::. : **:.::*** .: :::*****.:: ::*::*::** . * :** :*:::*:* ::*:*** ::: :.:*: *:. .: *.**:* *:*: ** ** *** : ******* . *. * **:.* *:. *:: *. *.. :***** :*****:.** ***** *. :.*: * *** : *** . :*:. .:* * ***: . * .:::* . :** *:** ** *.***:. * .:** * :* * :* **** : ** :***** **** * . . . : ****** * .*:* :** ***** . *.* **:* *::*:* :* ** :**** ***... : *:***:** : :**.. * **: :******** .** *: ***:****: . : *:* ** * *** **.*:*.* :* *:*:*::*: *** :** * ***: :* :. *: :*:*.* *: :*: *:****:**.: .. ** :::*.* :*: *** ::*** :** **: . . :. *::.* :*. *:**:* .*: : * *::** *.: * * :*:* * * :*: . . * *: :**: :. .** * ... : *: * *:*** : : : * .. ***::: : . : :* :* :* .:****:. ::**:: . *: ** *****: ::.: *: * ::*:**:** ::* * *. *:** :*::*..* * : * **:**: :.. *** * * . **:: ** *: : : :* *:::**.:::* :::.**: :*:***:* : : :.:::: :** :: * *. ******* ***: ****:.: .. : . *:*. : * * * :** * * * * : : *..** . . . . :: :. : :.: : . *. . .*.. * .. . ..: * ** * . . .. . :. : . ..: : . : :.: :. . . ", "identical_positions": 1419, "similar_positions": 1379, "identity": "28.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111115-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RZ42-1", "uniprot_id": "ALKL2_RAT", "id": "B2RZ42-1", "name": "ALK and LTK ligand 2", "aln": "------------------------------------------------MRVSGRPMLLALLLLLSTVG-DPGHAQPRGPADRQTLLRLLVELVQELKKFHIGDSKRLQLLGESDFALGRREATDYG-ADQEEQRVEIVPRDLRMKDKFLKHLTGPLYFSPKCSKHFHRLYHNTRDCTIPAYYKRCARLLTRLAVSPMCMER--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80UG6-1", "uniprot_id": "ALKL2_MOUSE", "id": "Q80UG6-1", "name": "ALK and LTK ligand 2", "aln": "------------------------------------------------MRVSGRPMLLALLLLLSTVG-DRGRAQSRGPADRQTLLRLLVELVQELKKFHIGDSKRLQLLGESDFALGRREATDYG-ADQEEQRVEIVPRDLRMKDKFLKHLTGPLYFSPKCSKHFHRLYHNTRDCTIPAYYKRCARLLTRLAVSPMCMER--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UX46-1", "uniprot_id": "ALKL2_HUMAN", "id": "Q6UX46-1", "name": "ALK and LTK ligand 2", "aln": "------------------------------------------------MRGPGHPLLLGLLLVLGAAGRGRGGAEPREPADGQALLRLVVELVQELRKHHSAEHKGLQLLG-RDCALGRAEAAGLG-PSPE-QRVEIVPRDLRMKDKFLKHLTGPLYFSPKCSKHFHRLYHNTRDCTIPAYYKRCARLLTRLAVSPVCMEDKQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FAP8-1", "uniprot_id": "AKL2B_DANRE", "id": "E7FAP8-1", "name": "ALK and LTK ligand 2b", "aln": "MCFALSLSIYKHTGTPPNKCRLNSALKRNRATVRLDIGQRGSLCPPFSMSAVRPPVFIGLLLLILTTG----YCKPRD-RDETSLLELLMDRVRQTQEHHS-EGNTQHPPQIIEHSLETKDVNKVTKSYQHERILEVFPRDLRQKDKFLKHLTGPLYFSPKCSKLFYKLYNNTRDCTIPAYYKRCARLLTRLAGSQRCTEG--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *:::.***:: :.* .:.* * :**.*::: *:: ::.* : : : : :* :. . . : :*:.***** ******************** *::**:********************** * * * ", "identical_positions": 68, "similar_positions": 37, "identity": "33.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111115-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49146-1", "uniprot_id": "NPY2R_HUMAN", "id": "P49146-1", "name": "Neuropeptide Y receptor type 2", "aln": "MGPIGAEADENQTVEEMKVEQYGP-QTTPRGELVPDPEPELIDSTKLIEVQVVLILAYCSIILLGVIGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSIYGTVYSLSSLLILYVLPLGIISFSYTRIWSKLKNHVSPGAANDHYHQRRQKTTKMLVCVVVVFAVSWLPLHAFQLAVDIDSQVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSE----VSVTFKAKKNLEVRKNSGPNDSFTEATNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97295-1", "uniprot_id": "NPY2R_MOUSE", "id": "P97295-1", "name": "Neuropeptide Y receptor type 2", "aln": "MGPVGAEADENQTV-EVKVEPYGPGHTTPRGELPPDPEPELIDSTKLVEVQVILILAYCSIILLGVVGNSLVIHVVIKFKSMRTVTNFFIANLAVADLLVNTLCLPFTLTYTLMGEWKMGPVLCHLVPYAQGLAVQVSTITLTVIALDRHRCIVYHLESKISKRISFLIIGLAWGISALLASPLAIFREYSLIEIIPDFEIVACTEKWPGEEKSVYGTVYSLSTLLILYVLPLGIISFSYTRIWSKLRNHVSPGAASDHYHQRRHKMTKMLVCVVVVFAVSWLPLHAFQLAVDIDSHVLDLKEYKLIFTVFHIIAMCSTFANPLLYGWMNSNYRKAFLSAFRCEQRLDAIHSE----VSMTFKAKKNLEVKKNNGPTDSFSEATNV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F951-1", "uniprot_id": "E7F951_DANRE", "id": "E7F951-1", "name": "Neuropeptide Y receptor type 2", "aln": "MDSLSLINGSSGSK-DLSIGEDSSDLTLN------HPLLELGDSTKLLGVQVVLILAYSTIILLGVVGNSLVIYVVYKFKTLRTVTNFFIANLAVADLLVNTLCLPFTLAYTLLREWKFGQVLCFTLPYAQGLAVHVSTITLNVIALDRHRCIVYHLDTRMSKDTCFLVIAITWVVSAVLASPLAIFREYGIVDLSPDNSIEVCGEKWP--DSSTDSTLYSISTLLLQYVLPLAIISFAYIRIWSKLRNHVSPVGRNDRHHRRR-KTTKMLVTMVVVFAVSWLPFHAFQLAIDIDHSVLDMKDFRLLYTVFHIVAMCSTFANPLLYGWMNRNYRSAFVAVFRCKERLDSLHTEGQPAATVRSKPKKALEAQD---MVTTHLNATDV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*..:. ... : ::.: .. * .* ** *****: ***:*****.:******:******:** ***::***************************:***: ***:* ***. :********:******.**************::::** .**:*.::* :**:***********.:::: ** .* .* **** :.* .*:**:*:**: *****.****:* ******:***** . .*::*:** * ***** :**********:******:*** ***:*:::*::*****:**************** ***.**::.***::***::*:* .:: *.** **.:. :. :**:*", "identical_positions": 231, "similar_positions": 93, "identity": "59.84%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111116-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6IQ19-1", "uniprot_id": "CCSAP_HUMAN", "id": "Q6IQ19-1", "name": "Centriole, cilia and spindle-associated protein", "aln": "MSPGS---GVKSEYMKRYQEPRWEEYGPCYRELLHYRLGRRLLEQAHAPWLWDDWGPAGSSEDSASSESSGAGGPAPRCAPPSPPPPVEPATQEEAERRARGAPEEQDAEAGDAEAEDAEDAALPALPVKDVEDKPEQQTRTRETDKSPTSTEPRQQPSALFARGNRKAVKSPQRSSSKIKE------NKHPFALYGWGEKQTDTGSQKTHNVCASAPVHEIHESALRAKNRRQVEKRKLVAQRQRAHSVDVEKNRKMKASSSENPWMTEYMRCYSARA-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8QZT2-1", "uniprot_id": "CCSAP_MOUSE", "id": "Q8QZT2-1", "name": "Centriole, cilia and spindle-associated protein", "aln": "MSPGS---GVKSEYMKRYREPRWDEYAPCYRELLRYRLGRRLLEQAHAPWLWDAWGPDSPSDSSASP------SPAPRGALGEPSAP--SAREEEQPVGERGA-ELRDAEE--------QDTVLPAPPKKDTEEKPEE-HKTKETDGAPSGPGPRQQPSALCARGSKKATRSPQRSTSKIKE------NKHPFALYGWGERQMDMGSQKTHNVCASASVHEIHESALRAKNRRQVEKRKLAAQRQRAHSVDVEKNQRVKPASAENPWLTEYMRCYSARA-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IQQ3-1", "uniprot_id": "A0A0R4IQQ3_DANRE", "id": "A0A0R4IQQ3-1", "name": "", "aln": "MSTNNNMMSKKTEYMKKYREPKWETFSKSYEDSLKYRLTRRLMEQTHRPFFAEGWDSGSDSSATSSPKHQEVNVPNAKHYISSSESKNETAEVLNSWKPQVNGEVHTDSSATLESAARLENGYKAVTSNGPSESFPKRRQRHRAPRSEPCYPNKDLDSDESRISISRKPSRAKSQPPGNSKERTSNRENRRPFIRYDWAERHIET--RRTPNIRASVSAGEIHRADVGVQTRRESKKNGRASDHWRARSADVEKSRRSGLSVADERWMTEYMRCFSARLR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**... . *:****:*:**:*: :. .*.: *:*** ***:**:* *:: : *.. . *. ::*. * .: .. . .* : .. *:. :: .. . *. *:. : : . * . :.. .:*. :: .:...: ** *::** *.*.*:: : ::* *: **... ***.: : .:.**: :*. .::: **:*.****.:: : ::: *:******:*** ", "identical_positions": 68, "similar_positions": 101, "identity": "24.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111116-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LPZ8-1", "uniprot_id": "A0ABK0LPZ8_RAT", "id": "A0ABK0LPZ8-1", "name": "Myoferlin", "aln": "MLRVIVESATNIPKTKFGKPDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPLDSSSSLVIVVKDFETIGQNKLIGTATVSLKDLIGDQNRSLPYKQISLLNEKGQDTGATIDLVIGYTPPSAPYP--NDP----SGTSVTGVGEEEEEDQGDEDRVDGMVRGPGPKGPSGTMSEAQLARRITKGKSSRRMLSNKPQDFQIRVRVIEGRQLCGNNIRPVVKVHVCGQTHRTR-IKRGNNPFFDELFFYNVHITPSELMDEIISIRVYNSHSLRADSLMGEFKIDVGFVYDEPGHAVMRKWLLLNDPE------DTSSGAKGYMKVSMFVLGTGDEPPSEKRDRDNDSDDVESNLLLPAGIALRWVTFLLKIYRAEDIPQMDDAFSQTVKEIFGGNADKKNLVDPFVEVSFAGKKVCTNIIERNANPEWNQVVNLQIKFPSMCEKIKLTVYDWDRLTKNDVVGTTYLYLSKIAASGGEVEDFSSSGTGAASYTANTGETEVGFVPTFGPCYLNLYGSPREYTGFPDPYDELNSGKGEGVAYRGRILVELNTFLEKKPPEKKLEPISNDDLLVVEKYQRRRKYSLSAVFHSATMLQDVGEAIQFEVSIGNYGNKFDATCKPLASTTQYSRAVFDGNYYYYLPWARTKPVVTLTSYWEDISHRLDAVNTLLVMAERLQSNIEAVKSGIQGKIPTNQLAELWLKLIDEVIEDTR-YTLPVTEGKANVTVLDTQIRKLRLRFLSQIHEAALRMRSEATDVKSTLLEIEEWLDKLMQLTEEPQNSMPDIIIWMIRGEKRLAYARIPAHQVLYSTSGGNASGKYCGKTQTILLKYPQEKNNGPKVPVELRVNIWLGLSAVEKKFNSFAEGTFTVFAEMYENQALVFGKWGTSGLVGRHKFSDVTGKIKLKREFFLPPKGWEWEGDWVVDPERSLLTEADAGHTEFTDEVYQNETRY-PGGEWKQAEDTYTDANGDKAASPNEMTCPPGWEWEDDAWTYDINRAVDEKGWEYGITIPPDNKPKSWVAAEKMYHTHRRRRLVRKRKKDLTQTASSTARAMEELEDREGWEYASLIGWKFHWKQRSSDTFRRRRWRRKMAPSETHGAAAIFKLEGALGADTTEDGDEKSLEKQKHSATTVFGANTPIVSCNFDRVYIYHLRCYIYQARNLMALDKDSFSDPYAHVSFLHRSKTTEIIHSTLNPTWDQTIIFDDVEIFGEPQTVLQNPPKVIIELFDSDQVGKDEFLGRSICSPLVKLNSETDTTPKLLWHPVMNGDKACGDVLVTAELILRNKD-GSNLPILPSQRAPNLYMVPQGIRPVVQLTAIEILAWGLRNMKNYQMASITSPSLVVECGGERVESVVIKSLKKTPNFPSSVLFMKVFLPKEELYMPPLVIKVIDHRQFGRKPVVGQCTIDHLDRFRCDPYAGKEDIVPQLKASLMSAPPCRDVIIEIEDTKPLLASKCLSSMSTALSKMASPRTVHLSEKEEEIVDWWSKFYASSGEHEKCGQYIQKGYSKLKIYDCELEDVADFEGLTDFSDTFKLYRGKS-DENEDPSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPDSVPQECTVRIYIVQGLQLQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTINPVFGRMYELSCYLPQEKDLKISVYDYDTFTRDEKVGETTIDLENRFLSRFGSHCGIPEQYCVSGVNTWRDQLRPTQLLQNVARFKGFPPPVLSE---DGSRIQYGGRDYHLDEFEANKILHQHLGAPEERLALHILRTQGLVPEHVETRTLHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFNITPRKAKTYYLRVIIWNTRDVILDEKSITGEDMSDIYVKGWISGSEENKQKTDVHYRSLDGEGNFNWRFVFPFDYLPAEQLCIVAKKEHFWSIDQTEFRVPPRLIIQIWDNDKFSLDDYLGFLELDLHRTIIPAKTSEKCSLDMIPDLKAMDPLKAKTASLFEQKSMKGWWPCYADKDGSR-----VMAGKVEMTLEVLNEREADERPAGKGRSEPNMNPKLDPPNRPETSFLWFTNPCKTMRFIVWRRFKWVIIGLLLLLILLLFVAVLLYSLPNYLSMKIVRPNA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q69ZN7-1", "uniprot_id": "MYOF_MOUSE", "id": "Q69ZN7-1", "name": "Myoferlin", "aln": "MLRVIVESATNIPKTKFGKPDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPLDSSSSLVIVVKDFETIGQNKLIGTATVSLKDLIGDQNRSLPYKQTSLLNEKGQDTGATIDLVIGYTPPSAPHP--NDP----SGTSVPGMGEEEEEDQGDEDRVDGIVRGPGPKGPSGTVSEAQLARRITKGKSSRRMLSNKPQDFQIRVRVIEGRQLCGNNIRPVVKVHICGQTHRTR-IKRGNNPFFDELFFYNVHITPSELMDEIISIRVYNSHSLRADCLMGEFKIDVGFVYDEPGHAVMRKWLLLNDPE------DTSSGAKGYMKVSMFVLGTGDEPPPEKRDRDNDSDDVESNLLLPAGIALRWVTFMLKIYRAEDIPQMDDAFSQTVKEIFGGNADKKNLVDPFVEVSFAGKKVCTNIIERNANPEWNQVVNLQIKFPSMCEKIKLTVYDWDRLTKNDVVGTTYLYLSKIAASGGEVE-------------ATTGETEVGFVPTFGPCYLNLYGSPREYTGFPDPYDELNSGKGEGVAYRGRIFVELNTFLEKKPPEKKLEPISSDDLLVVEKYQRRRKYSLSAVFHSATMLQDVGEAIQFEVSIGNYGNKFDATCKPLASTTQYSRAVFDGNYYYYLPWAHTKPVVTLTSYWEDISHRLDAVNTLLVMAERLQSNIEAVKSGIQGKIPANQLAEVWLKLIDEVIEDTR-YTLPVTEGKANVTVLDTQIRKLRSRFLSQIHEAALRMRSEATDVKSTLLEIEEWLDKLMQLTEEPQNSMPDIIIWMIRGEKRLAYARIPAHQVLYSTSGGNASGKYCGKTQTILLKYPQEKTNGPKVPVELRVNIWLGLSAVEKKFNSFAEGTFTVFAEMYENQALVFGKWGTSGLVGRHKFSDVTGKIKLKREFFLPPKGWEWEGDWVVDPERSLLTEADAGHTEFTDEVYQNENRY-PGGEWKQAEDTYTDANGDKAASPSEMTCPPGWEWEDDAWIYDINRAVDEKGWEYGITIPPDNKPKSWVAAEKMYHTHRRRRLVRKRKKDLTQTASSTARAMEELEDREGWEYASLIGWKFHWKQRSSDTFRRRRWRRKMAPSETHGAAAIFKLEGALGADTTEDGEEKGPEKQKHSATTVFGANTPIVSCNFDRVYIYHLRCYIYQARNLMALDKDSFSDPYAHVSFLHRSKTTEIIHSTLNPTWDQTIIFDEVEIFGEPQTVLQNPPNVTIELFDNDQVGKDEFLGRSICSPLVKLNSETDITPKLLWHPVMNGDKACGDVLVTAELILRNKD-GSNLPILPSQRAPNLYMVPQGIRPVVQLTAIEILAWGLRNMKNYQMASVTSPSLVVECGGERVESVVIKSLKKTPNFPSSVLFMKVFLPKEELYMPPLVIKVIDHRQFGRKPVVGQCTIDHLDRFRCDPYAGKEDIVPQLKASLMSAPPCREVVIEIEDTKPLLASK-------------------LSEKEEEIVDWWSKFYASSGEHEKCGQYIQKGYSKLKIYDCELEDVADFEGLTDFSDTFKLYRGKS-DENEDPSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPDSVPQECTVRIYIVQGLQLQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELSCYLPQEKDLKISVYDYDTFTRDEKVGETTIDLENRFLSRFGSHCGIPEQYCVSGVNTWRDQLRPTQLLQNVARFKGFPPPVLSE---DGSRIRYGGRDYHLDEFEANKILHQHLGAPEERLALHILRTQGLVPEHVETRTLHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFNITPRKAKKYYLRVIIWNTKDVILDEKSITGEDMSDIYVKGWISGSEENKQKTDVHYRSLDGEGNFNWRFVFPFDYLPAEQLCIVAKKEHFWSIDQTEFRVPPRLIIQIWDNDKFSLDDYLGFLELDLHRTIIPAKTSEKCSLDMIPDLKAMDPLKAKTASLFEQRSMKGWWPCYADKDGTR-----VMAGKVEMTLEVLNEREADERPAGKGRSEPNMNPKLDPPNRPETSFLWFTNPCKTMRFIVWRRFKWVIIGLLLLLILLLFVAVLLYSLPNYLSMKIVRPNA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NZM1-1", "uniprot_id": "MYOF_HUMAN", "id": "Q9NZM1-1", "name": "Myoferlin", "aln": "MLRVIVESASNIPKTKFGKPDPIVSVIFKDEKKKTKKVDNELNPVWNEILEFDLRGIPLDFSSSLGIIVKDFETIGQNKLIGTATVALKDLTGDQSRSLPYKLISLLNEKGQDTGATIDLVIGYDPPSAPHP--NDL----SGPSVPGMGGDGEEDEGDEDRLDNAVRGPGPKGPVGTVSEAQLARRLTKVKNSRRMLSNKPQDFQIRVRVIEGRQLSGNNIRPVVKVHVCGQTHRTR-IKRGNNPFFDELFFYNVNMTPSELMDEIISIRVYNSHSLRADCLMGEFKIDVGFVYDEPGHAVMRKWLLLNDPE------DTSSGSKGYMKVSMFVLGTGDEPPPERRDRDNDSDDVESNLLLPAGIALRWVTFLLKIYRAEDIPQMDDAFSQTVKEIFGGNADKKNLVDPFVEVSFAGKKVCTNIIEKNANPEWNQVVNLQIKFPSVCEKIKLTIYDWDRLTKNDVVGTTYLHLSKIAASGGEVEDFSSSGTGAASYTVNTGETEVGFVPTFGPCYLNLYGSPREYTGFPDPYDELNTGKGEGVAYRGRILVELATFLEKTPPDKKLEPISNDDLLVVEKYQRRRKYSLSAVFHSATMLQDVGEAIQFEVSIGNYGNKFDTTCKPLASTTQYSRAVFDGNYYYYLPWAHTKPVVTLTSYWEDISHRLDAVNTLLAMAERLQTNIEALKSGIQGKIPANQLAELWLKLIDEVIEDTR-YTLPLTEGKANVTVLDTQIRKLRSRSLSQIHEAAVRMRSEATDVKSTLAEIEDWLDKLMQLTEEPQNSMPDIIIWMIRGEKRLAYARIPAHQVLYSTSGENASGKYCGKTQTIFLKYPQEKNNGPKVPVELRVNIWLGLSAVEKKFNSFAEGTFTVFAEMYENQALMFGKWGTSGLVGRHKFSDVTGKIKLKREFFLPPKGWEWEGEWIVDPERSLLTEADAGHTEFTDEVYQNESRY-PGGDWKPAEDTYTDANGDKAASPSELTCPPGWEWEDDAWSYDINRAVDEKGWEYGITIPPDHKPKSWVAAEKMYHTHRRRRLVRKRKKDLTQTASSTARAMEELQDQEGWEYASLIGWKFHWKQRSSDTFRRRRWRRKMAPSETHGAAAIFKLEGALGADTTEDGDEKSLEKQKHSATTVFGANTPIVSCNFDRVYIYHLRCYVYQARNLLALDKDSFSDPYAHICFLHRSKTTEIIHSTLNPTWDQTIIFDEVEIYGEPQTVLQNPPKVIMELFDNDQVGKDEFLGRSIFSPVVKLNSEMDITPKLLWHPVMNGDKACGDVLVTAELILRGKD-GSNLPILPPQRAPNLYMVPQGIRPVVQLTAIEILAWGLRNMKNFQMASITSPSLVVECGGERVESVVIKNLKKTPNFPSSVLFMKVFLPKEELYMPPLVIKVIDHRQFGRKPVVGQCTIERLDRFRCDPYAGKEDIVPQLKASLLSAPPCRDIVIEMEDTKPLLASK-------------------LTEKEEEIVDWWSKFYASSGEHEKCGQYIQKGYSKLKIYNCELENVAEFEGLTDFSDTFKLYRGKS-DENEDPSVVGEFKGSFRIYPLPDDPSVPAPPRQFRELPDSVPQECTVRIYIVRGLELQPQDNNGLCDPYIKITLGKKVIEDRDHYIPNTLNPVFGRMYELSCYLPQEKDLKISVYDYDTFTRDEKVGETIIDLENRFLSRFGSHCGIPEEYCVSGVNTWRDQLRPTQLLQNVARFKGFPQPILSE---DGSRIRYGGRDYSLDEFEANKILHQHLGAPEERLALHILRTQGLVPEHVETRTLHSTFQPNISQGKLQMWVDVFPKSLGPPGPPFNITPRKAKKYYLRVIIWNTKDVILDEKSITGEEMSDIYVKGWIPGNEENKQKTDVHYRSLDGEGNFNWRFVFPFDYLPAEQLCIVAKKEHFWSIDQTEFRIPPRLIIQIWDNDKFSLDDYLGFLELDLRHTIIPAKSPEKCRLDMIPDLKAMNPLKAKTASLFEQKSMKGWWPCYAEKDGAR-----VMAGKVEMTLEILNEKEADERPAGKGRDEPNMNPKLDLPNRPETSFLWFTNPCKTMKFIVWRRFKWVIIGLLFLLILLLFVAVLLYSLPNYLSMKIVKPNV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T5L8-1", "uniprot_id": "A0A8N7T5L8_DANRE", "id": "A0A8N7T5L8-1", "name": "", "aln": "MLRVVVESAKGIPKKTIGVPDPIAGIIFRGEKKKTKAIDKELNPVWNEIIEFDLKGSPLDSSSFIEVVVKDYETIGKDKFIGSVKISLKELAAGQTRSLASKNTPLINEKKQEIGATINLTIAYEPPASTVPNLNDQNTGEANTKDTGAAEEEKAADSDEDAGDVADSGAPGVSPTGQPGKKDSKKVVRTTRKRQKALANKPQDFQIRIRVIEGRQLPGNNIKPVAKVSVCGQTHRTR-IRRGNNPFFDEIFSYNVNMLPSELFDESIMIRVYNASSLRADSLMGEFKLDVGYVYDETGHAIMRKWLLLGDPD------DAVSGARGYLKVSMFIVGTGDEPPVEKREANEEQDDIESNLLLPAGVALRWATLSLKIYRAEDMPQMDDAFAQTVKHIFGGTDDKKNLVDPFVEVNFAGKKVCTKIIEKNANPEWNQLIHLQVKFPSMCERIKLTAFDWDRLSKNDVIGTTYLNLTKIASSGGEIEETPSENGLPSSFNVDTTEAEVGFLPAFGPCYINLYGSPREFTGLPDPYEDLNYGKGEGVAYRGRVLIELSTQLNDKT-DKKVEDLSNDNILVAQKYQRRRKYSLCAVFHSACMLQEPGEPIQFEVSIGNYGNKLDSTCKPLASTTQYSCAVFDGNHYYYLPWADSKPVVILTSFWEDISHRLDSVNIILYISDRLQSNIISLKTAILAKVSDARLAEIWLKLVTQVIDDLSSYQLPDMEGKPNLTALDIQIKNLRDKTMTSVKEAAIRMREEAVDVRATMPDIEDWLDRLQQISEEPQNSMPDVIIWMLRGEKRVAYARIPANQVLYTTHSEQAIGKYCGRTQTIFMQYPMDKNKGLKIPVQLRVNMWLGLSAHEKKFNTFAEGTFSVYAEMYENQAQVFGKWGSTGLVSRHKFSDVTGKVKLKQERFMPPRSWDWEGDWFIDPERGLLTEADAGHSEFTDEVYQNETRF-PGGEWKSAAEPYTDVNGEKAQSPEEIECPTGWIWEDG-WNFDSNRAVDEKGWEYGVTIPPDDKPRSWVAAEKMYHIHRRKRLVRSRRK------TSEAPTIEKKDIGDGWEYSSLIGWKFHRKERSSDTFRRRRWRRKMAPSERVGASAIFNLEGALGIDDDEKGSKK-------DSAKLFGANTPTVFCRFDKSFSYHLRVYVYQARNLLPMDKDSFSDPYVHVSFLHASKTTEIIKSCLNPTWDQTLIFNDIEIYGDPQTIAYNPPNVVLEIYDSDQMGKDEAMGRCTCPPVVKLNPANPLIPKLFWFPISLKGRSAGEMLVAAELLLKEKANDANLPLVPPRRSENLYMVPQGIRPVVQLTAIEILAWGLRNMKAYQLAAVSSPSLVVECGGQIIQTATIKNIKKNPNFPGSVLFLKVLLPKDEMYTPPIVVKVIDHRPFGRKPVVGQCTINSLEEFRCDPYIDTTEVAMSAKVAMMAAAP-RDVVIDMGDRIPSPSKQ-----------------------EEDTVDWWSKFYASINELEKCGPYLQKGYDTLTVYNTELEAVPEFRGLTDFCNTFKLQRGKLEDEEEDPSVVGEFKGSFRVYPLSDDPNISDPPRQFRELPESCPQECLVRIHIIRCLDLQPKDNNGMCDPYIKISLGRKTIDDRDHYKPNTLNPDFGRVFELNCYIPQDKDLKISVYDYDLLSSDEKVGETVIDLENRLLSRFGSHCGIPKSYCVSGVNQWRDQLKPSQILQNLARMRGILAPQISD---DGSFLAFGGREYRLDELEANKSIHPHLGPPKERICLHVLRRQGLVPEHVETRTLYSSYQPTLSQGKIQMWVEIFPKNLGIPGPLCDITPRRPKQYFLRAVVWNTTEVILDETSITGENMSDIYVKGWMPGMEEDKQKTDVHYRSLDGDGNFNWRFVFGFDYLPAEQLCLVSRKEHFWSLDKTEFRIPPKLTIQIWDNDKFSLDDYLGTVELDLLHLIPPAKTPEKCSLSMLTQTGKN----LTPSSLFSQKSVRGWWPCAMEENGKK-----VLAGKVEMTLEVVEEKEADERPAGKGRDEPNMNPKLESPNRPDTSFLWFTNPCKTMKFIVWRKYKWLFIGLIILIPVILFIGILLYSFPNYLSMKLVKPF-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z0E5-1", "uniprot_id": "B7Z0E5_DROME", "id": "B7Z0E5-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSYMDDCFAGAPQEFLICITVHKAAQVGVTTGELYVRISLDKMTKSTKSFPNTENPFFNEYFVFEFHCTLTELLRLTILFELKKHMTYKKNVVVGELLVDLHSVWNQSNHGYFKKWGRLEAPIGENQTLENAVAPHGYLQLDLAIVSQHSPVSYALGSEEQDTQNLN-------KWTVDHDFDDIEKNLLTNVNIFAPSNIRYFVAFYRGYFIKQ--SNYMIQVSFAGFNGKTPVVKNTTTPVWNYEINFAWMYPSVAQRFLILIFAHEHLQWK-CVAEFELCLEEIAFNG---------------------------TPSLGPTYLHLYDPVN------------------PMIYVGRLLMELR-----------------SEMLTDSQPTHTLSSKTVPGLDETRFWHDDVYLIEFLPLMGHHILTSGTAYKISARLAEHTSNVLEG--------QLRTPLDRFKSAMNSKNFRREAPFQSCMFRVRLPDNRAKYES----DFFMLDIVNYMRSELDTFKLFQRKYPLQDDE---QAKCLKVIVNNILTRIKEGLDAHRFDHDVQPQRTTWDINRQLYLLDYFAKLPLELQNLKQKLRSCFLEHLDTSIGDVVNELQRLVAEIGSLSS---MARTQDEWPELVLSLSASGKDVGVCRLNAKLFLNLRNQDADQDQETLCWRLKSFSFKSAGCSHTCPNCGCTTAIVSGCLSIVVERERKRFLAVVNKEWAN---IEP---MLWQLNPEQTHFLCHVYIHQAKVRPGGEKKNICDSHLRVLFADQACETYTSPGTLSPIWNAVITFNWVSLPG------GIGLYLKNPP---LLSLEFYNSERSLPEDLVGMG-----SVAMSVISEDRASDSNWEDAGVFG-------CSKNPLRKLQRLKYLTPPPLK--WVPIARKGTLQAEVLMS--------------------AEIIQISMESLTTGQNDKKEPQLATGIPMAIRPTMQNFVLEVFFVGLRNYSKSSMSSAGKRKINLMMGDLVLSSGPSTARIRNSINFLVAYASG---------------VVSLPDQQDYWPAIIATDVLLSGFSS-ESILGAALIPNSSN--------FLQRDRTLKCVFK---------------------KEQEAAEASTTVSVDEDDEDEEEELEWEEEETKPSRISSWWMRLLFAFGLRPAPYANRHALRFHDDLDDHELVEEREFTWWTKFYNSMYWSAAEMCHEHKHRLV------------------------------------------------------IYYEELEKQAQFGYLQDWAVPVQLVHGVKFKKHGPPK--EDIYATLKLQLKLT---PCQCPVLEDPGGGGDMVRNMSNPIHPRHQSTLQSLGETV--KLLVRVYVVQGVQMRPRDVKGDSDCYVKLFLGGKTFSDRAHFSPNHSNPVFGRLFEMEATLPGDHMLQVMVYDHDKIK-DEVIGQTNIDLEDRWRTRHRATVGLANEYTKSGYNHWHDVKLPSEILIDLCQKRGIQAPYYYGNVIEVDGMLFGDETLISKDEELQERLSLAVLKNMDKLPSFGYK---LVPEHVETRSLCRDDFPNVEQGKLQLWIELFEANIYVPSP-IDITPVPPADFEVRVVVKNLVGIQAGDKNIFGKLMSDVYVIGWCED-EDKRQSTDIHYRSFAGDAAFNWRMVFGLKYSPNEDLMVIRRKAG--LLEEIEFKKPPIIYLQVWDKDVLTKDEYLAALELNLSNMYAPYPAAQLCKPYPK---------KRKRINLFKRKVINGWFPLQSNAHPSQRSQAAVQNGKMQLSIEVCTDVEAVNRPAGRGQDPP---MALEPPYRPDSSFNPLTHPCKSFQHILWPVIRKYVLWTLLILIVILGLVLFFSNLPAKLMTIPLE---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::. **:* * : * :. *: .. . .:: : *: *: : . :****:* * ::.: :**: * :.: : : : : ::**: :*: *:::..*. ::** * * : ..:**:::.: ::. . . . ::: :::: :: :: :: : : : . :: * *: : :::*.*** : * :::..:.* ** ::: :**:.::: : : ::* : :. * * :** .* *::** *::**.. . : * **:::** .::*. .: : . . . :..: : :: *:* :*:: . .:: * * :::: *::* .*: :.* :. ..* :: : ** * :: .. :.: . : . * * * : . *. :.:: : :. . :. . : ** : ::. * ** .: ::. . : * * : . : .:** : . . . * *:* * *. ::. : * .: :.* . . * . . :: :: ::: *:. . :* . ::* :* : :. ::.* .** :: : ***: * :.: . . . . : :: . *: : .. * : : ::*: .* : : *. ..** :.::* *.:.:*: : : ::*. . : :*:* : . : : :: : * . :.: . : :. *: :. . . . .:::.:: : . *.* . . : : .. :*.* * :: : . :. : :: * *: . . :* .* * : * : * ::. * * . : : :. :..*. .* : :: . . : * :. : :* : : .* . * . :: . * :: :* . : : * : . ::. ::: . *: *:** : .*: : *. : .:* . ::.* :: : **::::: ::::*:* :* .* *:*: ** *.:.** *: ** ** ***::*:.. :* :: *:: ***:* :. ** :*:* ****:* :*. : *:.:.* ** * *:* *:::* ::.: :*: * : . : :*.. .: * :: : : ::: . : *********:* *.:.***:*:*:::* .: *.* :*** . : :*.:: * : .:..* *: ***:** ** . *:.:*.**:****: *:. ****:** :.* * *:* :: :* ::: **: ** : :*:**:* :: *:**. :**:* . * :.: * . .**.:: :.**:* : . : * **:::::*: : ** :****:*:. * *: * **::** :*:***:::.*:* : .: :::: ::* : ::: .:* * :. ", "identical_positions": 301, "similar_positions": 590, "identity": "14.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111117-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A6G2-1", "uniprot_id": "D4A6G2_RAT", "id": "D4A6G2-1", "name": "Semaphorin-4G", "aln": "MWGRLWPLLFSFLTATAVPGPSLRRPSRELDATPRMTISYEELSWIRHFKGQAQNYSTLLLEEASQRLLVGARGALFSLSARDIGDG-THKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNASHFYACGTHAFQPLCAAIDAEAFILPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPDIRRSRHPHSLRTEEAPMHWLNDAEFVFSVLVRESKTSVVGDDDKIYYFFMER--EEGSSSFTQSRSSHRVARVARVCKGDLGGKKILQKKWTSFLKARLICHIP----QYETLRGVCSLDADTSSHTHFYAVFTLTTQWKTLEASAICRYDLAEIQAVFTGPFMEYQDGARRWGRYEGGVPEPRPGSCITDSLRSRGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKRNVRYTHLTGTHVSIPAGPTYDLLFLGTADGWIHKAVVLGSGMHIIEEIQVFRESQSVDNLVISPMQHSLYVGAASGVIQFPLSSCSRYRSCYDCILARDPYCGWDSSTHACMVATTIANRTALIQDIERGNRGCEGSRDAGPPPPFKTRSVLRGDDVLLPCDQPSNLARALWLLNGSKSLSDGQD-GYRVGVDGLLVTDTQLEHSGNYGCYAEENGLRMLLASYSLIVRPATP-------------------------------------APAPQAPATPGAQLAHDMRLFYVVAIAILGGLCLILASSLLYVA-CLRGGRRGRRRKYSLGRAG---RAGGSAVQLQTVSGQCPGEEDDGDDGEGAGS----LESGCLQIIPGEGAPAPPPP--PPPPPPAELTNGLVA-LPSRLRRMNGNSYVLLRQSNNGVPAGP-CSFAEELSRILEKRKHTQLVEQLDESSV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUH7-1", "uniprot_id": "SEM4G_MOUSE", "id": "Q9WUH7-1", "name": "Semaphorin-4G", "aln": "MWGRLWPLLFSFLTVTAVPGPSLRRPSRELDATPRLTISYEELSQIRHFKGQTQNYSTLLLEEASERLLVGARGALFSLSARDIRDR-THKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNATHFYACGTHAFQPLCAAIDAETFILPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPDIRRSRHPHSLRTEEAPMHWLNDAEFVFSVLVRESKTSAVGDDDKIYFFFMER--EEGSSSFTQSRSSHRVARVARVCKGDLGGKKILQKKWTSFLKARLICHIP----QYETLRGVCSLNADTSSHTHFYAVFTLTTQWKTLEASAICRYDLAEIQAVFTGPFMEYQDGARRWGRYEGGVPEPRPGSCITDSLRSRGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKRNVRYTHLTGTHVSTPAGPTYDLLFLGTADGWIHKAVVLGSGMHIIEEIQVFREPQSVDNLVISPMQHSLYVGAASGVLQFPLSSCSRYQSCYDCILARDPYCGWDSSIHACMVATTVANRTELIQDIERGNRGCEGSRDAGPPPPLKTRSVLRGDDVLLPCDQPSNLARALWLLNGSKSLSDGQD-GYRVGVDGLLVTDTQLEHSGNYGCYAEENGLRMLLASYSLTVRPATP-------------------------------------APAPQAPATPGAQLAHDMRMFYVVAIAILGGLCLILASSLLYVA-CLKGGRRGRRRKYSLGRAG---RAGGSAVQLQTVSGQCPGEEDEGDDGEGTGG----LESGCLQIIPGEGAPAPPPP--PPPPPPAELTNGLVA-LPSRLRRMNGNSYVLLRQSNNGVPAGP-CSFAEELSRILEKRKHTQLVEQLDESSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NTN9-1", "uniprot_id": "SEM4G_HUMAN", "id": "Q9NTN9-1", "name": "Semaphorin-4G", "aln": "MWGRLWPLLLSILTATAVPGPSLRRPSRELDATPRMTIPYEELSGTRHFKGQAQNYSTLLLEEASARLLVGARGALFSLSANDIGDG-AHKEIHWEASPEMQSKCHQKGKNNQTECFNHVRFLQRLNSTHLYACGTHAFQPLCAAIDAEAFTLPTSFEEGKEKCPYDPARGFTGLIIDGGLYTATRYEFRSIPDIRRSRHPHSLRTEETPMHWLNDAEFVFSVLVRESKASAVGDDDKVYYFFTERATEEGSGSFTQSRSSHRVARVARVCKGDLGGKKILQKKWTSFLKARLICHIP----LYETLRGVCSLDAETSSRTHFYAAFTLSTQWKTLEASAICRYDLAEIQAVFAGPYMEYQDGSRRWGRYEGGVPEPRPGSCITDSLRSQGYNSSQDLPSLVLDFVKLHPLMARPVVPTRGRPLLLKRNIRYTHLTGTPVTTPAGPTYDLLFLGTADGWIHKAVVLGSGMHIIEETQVFRESQSVENLVISLLQHSLYVGAPSGVIQLPLSSCSRYRSCYDCILARDPYCGWDPGTHACAAATTIANRTALIQDIERGNRGCESSRDTGPPPPLKTRSVLRGDDVLLPCDQPSNLARALWLLNGSMGLSDGQG-GYRVGVDGLLVTDAQPEHSGNYGCYAEENGLRTLLASYSLTVRPATP-------------------------------------APAPKAPATPGAQLAPDVRLLYVLAIAALGGLCLILASSLLYVA-CLREGRRGRRRKYSLGRAS---RAGGSAVQLQTVSGQCPGEEDEGDD-EGAGG----LEGSCLQIIPGEGAPAPPPP--PPPPPPAELTNGLVA-LPSRLRRMNGNSYVLLRQSNNGVPAGP-CSFAEELSRILEKRKHTQLVEQLDESSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RFA4-1", "uniprot_id": "A0A8M1RFA4_DANRE", "id": "A0A8M1RFA4-1", "name": "", "aln": "MGQTTMLNLILVGYLIPVIWCFPFGPVLDMDVTPRTTVRVNGLLGCNHFQGAALNYSSLLLEDGPGVLYVGAREAIYKLDTANISDTNNSLTLEWAASADQKRQCLSKGKNNQTECYNHVRFLDRYNDTHLYTCGTHAFRPRCAYIDVARFTFVR-FEEGKEKCPYDPTKGYTGFIIDGEMYSASQYEFRNIADIRRNFPFPNLRIDDSPTRWLLESDFVGSALLRESINSSIGDDDKLYFFFTER-----NTEPTAYSIQTKVARVARVCKGDIGGQRTLQRKWTSFLKARLVCAIPDYELQFNVLRSVFVVEGSNVHDSVFYGIFGL--EWRNVKMSAVCRYSLKDIQTAFNGPFMELQDS--KWREYTGKVPDPRPGSCITDEHRGKLINSSRDLPDNTLNFVRRHPLMSTQIQPVEGRPLLLQKAADYTKIIVQQVEGLDGRTYDMLFIGTDEGWLQRAVKIIDRVHIIEELQLFQEKQPIINMVISQKQNSIYVSGASGLVQVPLSSCERYTSCYDCVFARDPLCGWDG--RMCAEIASYANRSSLVQDIQMGRRGCSNITSDG-FVMHRTRAVMAGDDVLLQCEIRSNLATPQWTLNSQELKGYGVDSGYRTGTDGLLIIGAQNQQSGHYRCYAVENSVWVPIRSYIVRVQPVPPPASHLSGSPTALPESFFTTTTVPTPSPSSGPVEQLLSPPPAPLPSDPEFQTYKHMEAMYISLVAVLGGLCLVLTVLLLYVSFCAQNSLDAKYSQQALSITTPTERKRSSHFELKTISSHCNGRTEGRSRAMSRDEEFLQIVPLDIQTTPSEEPPPAPPLPMPPPLPASEYANGLSATLPSVLRKINGNSYVLLGQADSETTSPLYHSFTEELNRILEKRKHTQLDIQPDESSV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *: . .* * ::*.*** *: : * .**:* : ***:****:.. * **** *::.*.: :* * :.* **.: : :* .*********:******:* * :*:*:******:* ** **. * : ************::*:**:**** :*:*::****.*.****. .** :::* :** :::** *.*:*** * :*****:*:** ** . . * . :***********:**:: **:**********:* ** ::.**.* ::... : **. * * :*:.:: **:***.* :**:.* **:** **. :* .* * **:*********. *.: ***:***. .*:**: ****: : *..******:: **:: * * ***:**:** :**:::** : . :***** *:*:* *.: *:*** *:*:**...**::*.*****.** *****::**** **** : * :: ***: *:***: *.***.. . * :**:*: ****** *: **** . * **.. . * . ***.*.****: .:* ::**:* *** **.: : ** : *:*..* .*.. *: * * .:. :*: :* ******:*: ****: * : . .: : :*. : * .* .:*:*:*.:* *. : . . . : :* *.* .*..** *** *.:* :*** * *** **::******** *::. ..: **:***.*********** * *****", "identical_positions": 389, "similar_positions": 222, "identity": "43.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111117-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P10683-1", "uniprot_id": "GALA_RAT", "id": "P10683-1", "name": "Galanin peptides", "aln": "MARGSVILLAWLLLVATLSATLGLGMPTKEKRGWTLNSAGYLLGPHAIDNHRSFSDKHGLTGKRELPLEVEEGRLGSVAVPLPESNIVRTIMEFLSFLHLKEAGALDSLPGIPLATSSEDLEQS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P47212-1", "uniprot_id": "GALA_MOUSE", "id": "P47212-1", "name": "Galanin peptides", "aln": "MARGSVILLGWLLLVVTLSATLGLGMPAKEKRGWTLNSAGYLLGPHAIDNHRSFSDKHGLTGKRELQLEVEERRPGSVDVPLPESNIVRTIMEFLSFLHLKEAGALDSLPGIPLATSSEDLEKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22466-1", "uniprot_id": "GALA_HUMAN", "id": "P22466-1", "name": "Galanin peptides", "aln": "MARGSALLLASLLLAAALSASAGLWSPAKEKRGWTLNSAGYLLGPHAVGNHRSFSDKNGLTSKRELRPE-DDMKPGSFDRSIPENNIMRTIIEFLSFLHLKEAGALDRLLDLPAAASSEDIERS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EZ53-1", "uniprot_id": "GALA_DANRE", "id": "E7EZ53-1", "name": "Galanin peptides", "aln": "MHRCVGGVCVSLIVCAFLTETLGMVIAAKEKRGWTLNSAGYLLGPHAIDSHRSLSDKHGLAGKREMPLD-EDFKTG--ALRIADEDVVHTIIDFLSYLKLKEIGALDSLP---SSLTSEEISQP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * : *:: . *: : *: .:*******************:..***:***:**:.***: : :: : * :.:.::::**::***:*:*** **** * : :**::.:.", "identical_positions": 52, "similar_positions": 40, "identity": "41.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111117-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZDR9-1", "uniprot_id": "D3ZDR9_RAT", "id": "D3ZDR9-1", "name": "Nuclear exosome regulator NRDE2", "aln": "MLREFCGREAERVKPHRVLRTTFPRGLRESASSNQSSPDGAISVAEVVVRPVIMALFPAFAGVSEASGDGASRK--ELDWLSNPSFRVG-NLTSLSRQTEEVPALASEASP-----LTRSPLKSELSDESDTNEKLTQISKKKKKEKKKKRKHQHHKKTKRRHEQSSSSGSGSDTEAGKDRASRSIRDSQ-ESEKARQGSNAVPAAPATG-HSSIWLEDIYTLT-DVFRTDKKPDPANWEYKSLYRGDIARYKRKGDSCLGINPKKQCISWEGASAAKKHSHRHLERYFTKKNVALLRTEG---IAVCSNPEPSSSEPAPFIPVKDSADVAT--PVTTWLNPLGIYDQSTTQWLQGQGPAEPE-LKQPDSQQERDSAALKARVEEFNRRVRENPRDTQLWMAFVAFQDEVMRSPG-IYALGEGEQEKHRKSLKLLLEKKLAVLERAIESNPSSVELKLAKLQLCSEFWEPSALTKEWQKLLFLHPNNTSLWQRYLSFCQSQFGTFSVSKLHSLYGKCLSTLSAVKDGSMLSHPVLPGTEEAMFGLFLQQCHFLRQAGHSEKVVSLFQAMVDFTFFKPDSVKELPTKVQVEFFEPFWDSGEPRVGEKGARGWRAWMHQQERGGWVLVNPDEDDEEPEEEDQEIKDKTLPRWQIWLAMERSRDQRHWRPWRPDKTKKQ-TEEDCEDPERQVLFDDVGQSLIRLSSPDLQFQLIEAFLQFLGVPSGFLP--PASCLYLAMDES----------SIFESKLYDEKPLTYFNPLFSGISCVGYMEQLDCPRWTKGHNREGEEFVRNVFHLVLPLFSGKQKCQLCLSWLRYEIAKVIWCLHTK-KKRLKSQGKNCKKLAKSLLKEPENRNNLCLWRQYAHLEWLLGNTEDARKVLDAALSMAGSSDLKDRELCELSLLYAELEVELSPDSRGATTG-RAVHVLTRLTESSPCGPYTGQVSSTQVLKARKAYEHALQDCLG-QSCASSPPTAESLDCLGSLVKCFMLFQYLTVGIDAAVQVYRQVFSKLEGSALLEGPGPEDSASSQSVTSVLEAVTLMHTSLLRFHMNICVYPLAPLRETLSDALKLYPGNQGLWRAYVQIQNKSHSANKTRRFFDTVTRSAKHLEPWLFAIEAEKLRKRLVESVQRVGGR-------EVHATIPETGLTHRIRALFENAIRSDQGGQCPLLWRMYLKFLVSLGNKER-SKGVFYKALQSCPWAKVLYMDAVEYFPEELQEILDVMTEKELRVRLPLEELELLLED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80XC6-1", "uniprot_id": "NRDE2_MOUSE", "id": "Q80XC6-1", "name": "Nuclear exosome regulator NRDE2", "aln": "-----------------------------------------------------MALFPAFADVSEASGDGAFRK--ELDWLSNPSFRVG-NLTSLSRQTEEVTALASEGSPPPRYSFIRSPLKSELSGESNTSEKLAQTSRKKKKEKKKRRKHQHHRKTKRRHEQLSSSGSESDTEAGKDRASRSIRDDQKEAEKPCQGSNAAAAVAAAAGHRSIWLEDIHDLT-DVFRTDKKPDPANWEYKSLYRGDIARYKRKGDSCLGINPKKQCISWEGASAAKKHSHRHLERYFTKKNVGLMRTEG---IAVCSNPEPASSEPVTFIPVKDSAEAAT--PVTSWLNPLGIYDQSTTQWLQGQGPAEQE-SKQPDSQQDRENAALKARVEEFNRRVRENPWDTQLWMAFVAFQDEVMRSPG-IYALGEGEQEKHRKSLKLLLEKKLAVLERAIESNPGSVELKLAKLQLCSEFWEPSALAKEWQKLLFLHPNNTSLWQRYLSFCQSQFGTFSVSKLHSLYGKCLSTLSAVKDGSMLSHPVLPGTEEAMFGLFLQQCHFLRQAGHSEKVISLFQAMVDFTFFKPDSVKELPTKVQVEFFEPFWDSGEPRVGEKGARGWRAWMHQQERGGWVLITPDEDDEEPEEEDQEIKDKTLPRWQIWLAVERSRDQRHWRPWRPDKTKKQ-TEEDCEDPERQVLFDDIGQSLIRLSSPDLQFQLIQAFLQFLGVPSGFLP--PASCLYLAMDES----------SIFESELYDEKPLTYFNPSFSGISCVGSMEQLGRPRWTKGHNREGEEFVRNVFHLVLPLLAGKQKSQLSLSWLRYEIAKVIWCLHTK-KKRLKSQGKSCKKLAKNLLKEPENRNNFCLWKQYAHLEWLLGNTEDARKVFDTALSMAGSSELKDRELCELSLLYAELEMELSPDSRGATTG-RAVHILTRLTESSPYGPYTGQVSSTQVLKARKAYELALQDCLG-QSCASSPAPAEALDCLGSLVRCFMLFQYLTVGIDAAVQIYGRVFAKLKGSARLEDPGPEDSTSSQSLTNVLEAVSMMHTSLLRFHMNVCVYPLAPLRETLSDALKLYPGNQVLWRAYVQIQNKSHSANKTRRFFDTVTRSAKHLEPWLFAIEAEKLRKKLVESVQRVGGR-------EVHATIPETGLTHRIRALFENAIRSDKGNQCPLLWRMYLNFLVSLGNKER-SKGVFYKALQSCPWAKVLYMDAMEYFPDELQEILDVMTEKELRVRLPLEELELLLED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H7Z3-1", "uniprot_id": "NRDE2_HUMAN", "id": "Q9H7Z3-1", "name": "Nuclear exosome regulator NRDE2", "aln": "-----------------------------------------------------MALFPAFAGLSEAPDGGSSRK--ELDWLSNPSFCVG-SITSLSQQTEAAPAHVSEGLP-----LTRSHLKSESSDESDTNKKLKQTSRKKKKEKKKKRKHQHHKKTKRKHGPSSSSRSETDTDSEKDKPSRGVGGSKKESEEPNQGNNAAADT----GHRFVWLEDIQAVTGETFRTDKKPDPANWEYKSLYRGDIARYKRKGDSCLGINPKKQCISWEGTSTEKKHSRKQVERYFTKKSVGLMNIDG---VAISSKTEPPSSEPISFIPVKDLEDAA---PVTTWLNPLGIYDQSTTHWLQGQGPPEQE-SKQPDAQPDSESAALKAKVEEFNRRVRENPRDTQLWMAFVAFQDEVMKSPG-LYAIEEGEQEKRKRSLKLILEKKLAILERAIESNQSSVDLKLAKLKLCTEFWEPSTLVKEWQKLIFLHPNNTALWQKYLLFCQSQFSTFSISKIHSLYGKCLSTLSAVKDGSILSHPALPGTEEAMFALFLQQCHFLRQAGHSEKAISLFQAMVDFTFFKPDSVKDLPTKGQVEFFEPFWDSGEPRAGEKGARGWKAWMHQQERGGWVVINPDEDDDEPEEDDQEIKDKTLPRWQIWLAAERSRDQRHWRPWRPDKTKKQ-TEEDCEDPERQVLFDDIGQSLIRLSSHDLQFQLVEAFLQFLGVPSGFTP--PASCLYLAMDEN----------SIFDNGLYDEKPLTFFNPLFSGASCVGRMDRLGYPRWTRGQNREGEEFIRNVFHLVMPLFSGKEKSQLCFSWLQYEIAKVIWCLHTKNKKRLKSQGKNCKKLAKNLLKEPENCNNFCLWKQYAHLEWLLGNTEDARKVFDTALGMAGSRELKDSDLCELSLLYAELEVELSPEVRRAATA-RAVHILTKLTESSPYGPYTGQVLAVHILKARKAYEHALQDCLG-DSCVSNPAPTDSCSRLISLAKCFMLFQYLTIGIDAAVQIYEQVFAKLNSSVFPEGSGEGDSASSQSWTSVLEAITLMHTSLLRFHMKVSVYPLAPLREALSQALKLYPGNQVLWRSYVQIQNKSHSASKTRRFFDTITRSAKPLEPWLFAIEAEKLRKRLVETVQRLDGR-------EIHATIPETGLMHRIQALFENAMRSDSGSQCPLLWRMYLNFLVSLGNKER-SKGVFYKALQNCPWAKVLYLDAVEYFPDEMQEILDLMTEKELRVRLPLEELELLLED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5I2-1", "uniprot_id": "A0ACD6B5I2_DANRE", "id": "A0ACD6B5I2-1", "name": "", "aln": "-----------------------------------------------------MALFPSFSGLSGSNSSAESKAPADLEWLSNQSFSTEDALKTHQRATDRARAETEEPAG---------------TSEEKHKERGDNHGKSKKRKKEKKKKHKK----KRSRDNSESSGSESDTIYPSDLLKKENTDREEAQVRVS--------------ETFMWLDDLQTPTDSPFCIDRRADRANWQYKSLYRGDIARYKRKGGSCLGLDLRTQAVTWIDGGPEKKRVDKKAERYFSSSTRQLLQTRGLLALPILSEGSATNSDPYIKLAVCAEEQGSSTQTPESWVNPLGIYDPGTTLWLEGKGQPEVKGEQQSTEAQESNSTLLSARVEEFNRNLRENPTDIKLWLDFVHFQDELAFGSGSFSSAGDCDAEMRKMSLRAVLEKKLSIMDRAVESNPSDVDLKLEKLRLCKELWEPAVLQKEWKKLVFIHPNSAPLWKKYLLFTQSHFSTFSVSKVNGVFGKCLSTLSAVQDGSMVSHPPLPGTQEDLLDIFLQQCHFLRQAGHTEKAVCLFQALLDFTFFKPDNVKNLATRQQVDFFEPFWDSGEPRIGERGARGWKAWMLQQEKGGWVIPPEPDDDEEEEQEDSEIKDKTWPKWKIWLDVEASREANQWLPWRPDKTKGQ-SEEDCEDPDRQVLFDDIGPSMIRVDRADLQAQLILAFLQFLGLPGALTKFFTASSSSFLLDDL----------TFLEEGPDPERPLTSYDLPVTGIRAVGHMTCLSGCRRQAGLCKAGEEFLHNVLHQTLRLVPAQDQAAITLCWLQYEKLKVLRCLRSGNKRQMKSQGKRSKRLAKRLLKEPENRGSLALWREYAHLEWLLGNLEEARKVFDTALSMGVSRGLNDHVLCKLCFLYAQLEVEQALSSETVSTFPKAVYILTKLAEGASYTPFSGQINPVVILKARKAYEQALLSILPEQNTDSNARASKKHNRTSSLIGCFGLFQYLTMGIDAAQAVYSQAIQKLIPSHFNSEAADGSRRRS-TIFADCEAVAVQHVALLRHHTNTNVFPLSRLRLALTDALSLLPSSASLWHLYLQTENHYHSAGRTRRFFHSMAKKTDSVVPYLFAITAEQRLKQLLDSVQRSRLPG------EALPTLPVNGLSNRIRCLFESATGAEHGAHCPLLWRMYLNFMVCDGNADR-GSGIFYKALQEVPWVKGLYMDAVQLFPERVQEFLDLMTEKELRLRMPMEEVDILLEE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VXW9-1", "uniprot_id": "Q9VXW9_DROME", "id": "Q9VXW9-1", "name": "Protein NRDE2 homolog", "aln": "-----------------------------------------------------MSLFPAYGAGRTSAAGSAKQT-------------------------------------------------------TKPGEEEPSTGGNWKKNESYIKKHVN------IATQGPESDSSSSTEDSEDEADKRKQDDVTKTKNVHRG------------------KTLEFDSSDGFYVDKVGNSSYRNIKTLKKPARPRYKTR-------------MKRLGDGKYNPHDFSRAHSKFSLKRSRYVREKL-----------------------------------------------------------------IADAPSEDEVSRLQEQLIRTKVLVQQEPEVLDHWLQLHRLLNLNLDKAN----------------RLAVAEQQIHSLETAMEHHPSNQQILRLYTHVANATYQANEVARRFEKMLKRNPFQYTLWSNLIMITQGDMACCNVSAVLRIYEYSMRRMHVGHNDEITRRFIIKETDVIMLKLFHNCLLFLRQSGHTNWMFALIRLSMELNFP----------------YLTFECLQAHAGREKALIGFEEVVLRSG---------------------------MPMPEIWTRVEQLRQAYCFLPLKDKLASSTNVFKNKMNAERYFCSDKLVPYVHALKSQNNRLHLVLVVVQLMKLPLIRSAS-LADKLNPCIEDFGESEAIEMLFAAIVDRHSYAVASLQYQFDAAMIDLAREMSVTPSYMPHLVGHKLYADTVSNMLLKCVEVFIGEESKRRLLLILYLRFQKLLIVLHKSMGKLTKKFFKDKRTRMRKLINLTENRNVISFYTEQALCEIEAKHYRLGFSIISRIITKKSEESSCISCVDTMHLYLVCAELHIHRGRISKAIGILVSLCLEKHAGVKQTTVYSKEQVLKGLRNAEKMVRAELKSLDT-QPAEMSLEEYFQPNKLLILLRAICLIEVLNNRRHKEARMWLNDLQNNEFGPEAVKDSERKRFLREQIMEIQMLHLRLSFLVFGEVEFYTGFKKIKLHELLENGLEEFPRNMVFLQLWASLKSIMWHKQRSR-----LIRTKAGIASLAHLVVAIHNRFGIVDTNDKFSKEATRKMVCNRLVSIVETFLPTNLDRLDVEEEHYRILRRNSIYWRLYMIALSKTNASFRRSKEVLIMAMDECPWDKSLLMEGAKVLPVKLASLQDLMTEKEIRIFAMPEEVDVLRGF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:***::. : .. : . :. . . . *:::. :** : .* * :.* .* .: . . . : : . * *: : : : *:* : .*** : :. . . : : : . *: . :. . : : : *. :: . : ::::* . *: : : : .. : *::: :: *:* : .. :: ::.. ::. : :.::*:: :* . .**.. : : *..:. .:* : :: .: : . ::..: : : *: :: :* : ****:**:: ..*:: :::.* : .* *:. *:. : :. * :** * *: : * : . :. :: :.:* . *.: : :. : : :*: ..:*:: :* *. ::: : : . . :: : . * : : : *:: : :. .::. : * . *:: *:. : *. * : : *:: .** . :.:: : * * : . . .::. : . : : : . *:. : . * : : :: : : :*.* . * . : . . * .: *:: *. . :: . : : . . . :: : *: * :.*. * . : : : . :. ::* : :. : . . : * : :::: :: : :: . * .: * . : .: **:*: : . * .. :: *::. ** * * ::. : :* .: .: *:*****:*: **:::* ", "identical_positions": 104, "similar_positions": 331, "identity": "8.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111118-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVR3-1", "uniprot_id": "CD302_RAT", "id": "Q5FVR3-1", "name": "CD302 antigen", "aln": "--------------MPHAALSSLVL--LSLATAIFADCPSS--IWVQFQGSCYTFLQVTINVEN---IEDVRKQCTDHGADLVSIHNEEENAFILDTLQKRWKGPDDLLLGMFYDTDDASFKWFDQ-SNMTFDKWAD---EDG-EDLVDTCGFLYAKTGEWRKGNCEMSSVTGTLCKTAIPYDKKYLSDNHILISTLVIASTVTLAVLGAVIWFLYRRSARSG---FTS-FSPAPQSPYSDGCALVVSEEDEYSVQLD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DCG2-1", "uniprot_id": "CD302_MOUSE", "id": "Q9DCG2-1", "name": "CD302 antigen", "aln": "--------------MPHAALSSLVL--LSLATAIVADCPSS--TWVQFQGSCYAFLQVTINVEN---IEDVRKQCTDHGADMVSIHNEEENAFILDTLQKRWKGPDDLLLGMFYDTDDATFKWYDH-SNMTFDKWAD---QDG-EDLVDTCGFLYTKTGEWRKGDCEISSVEGTLCKAAIPYDKKYLSDNHILISTLVIASTVTLAVLGAIIWFLYRRNARSG---FTS-FSPAPLSPYSDGCALVVAEEDEYAVQLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IX05-1", "uniprot_id": "CD302_HUMAN", "id": "Q8IX05-1", "name": "CD302 antigen", "aln": "--------------MLRAALPALLLPLLGLAAAAVADCPSS--TWIQFQDSCYIFLQEAIKVES---IEDVRNQCTDHGADMISIHNEEENAFILDTLKKQWKGPDDILLGMFYDTDDASFKWFDN-SNMTFDKWTD---QDDDEDLVDTCAFLHIKTGEWKKGNCEVSSVEGTLCKTAIPYKRKYLSDNHILISALVIASTVILTVLGAIIWFLYKKHSDSR---FTTVFSTAPQSPYNEDCVLVVGEENEYPVQFD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U371-1", "uniprot_id": "A0AB32U371_DANRE", "id": "A0AB32U371-1", "name": "", "aln": "MISALQNMESSARHVTLFYIALIILTGYSARGEDDNDCPADGRTWLPFGRNCYHFIHGAEDVAKSYSLQDAKDMCR--GYELLTVKSADENNFVVNYSPSVWKGKMNVWLGLYYDSDRDVFRWHEDDSVLGFSNWEDGGDDETDLPLMDTCVALHSNTGKWENISCTDEPENGVVCQTKAVVIRSNQSK--PLLSALVIISVVLILAVSAVIWFVQQRHNPGSSILNLIEYHPPFRSPSADQTCLVEAEEINDMP---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. ::* . ***:. *: * .** *:: : .* . ::*.:. * * ::::::. :** *::: . *** :: **::**:* *:*.:. * : *.:* * :: *:*** *: :**:*.: .* .. *.:*:: :. *. *:*:*** *.* : .:.*:***: :: . : .. ** : ** .** : ", "identical_positions": 59, "similar_positions": 80, "identity": "22.87%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111118-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q587K4-1", "uniprot_id": "LRC73_RAT", "id": "Q587K4-1", "name": "Leucine-rich repeat-containing protein 73", "aln": "MLPSSIQISGEPLSGAEVRDICRGLRDNAVRLLSLRGCRLCDRDFGRICRALAGATSLAQLNLNLGVVSSPSRIKQLAEALRTNRSIQSLFLHGSPLTDAGLALLNPALALHPALVALDLGDCMLGDEAINLICGLLPPDGAKSGLKELTLSANPGITPKGWSRLAIAVAHSSQVRVLNLDYNPLGDHVAGMLAVAVASSRTLEVLDLEGTGLTNQSAQTLLDMVENYPTALRSLVLAENSISPELQQQICDLLSEGEEEEEMAGGAADTQEWGRGREPAAHQRGGSSWKCPSDPNSQMVLMTSGLG--DSLLAETEM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5JTD7-1", "uniprot_id": "LRC73_HUMAN", "id": "Q5JTD7-1", "name": "Leucine-rich repeat-containing protein 73", "aln": "MLPSSIQISGEPLSGAEVRDICRGLRDNAVRLLSLRGCRLCDRDFGRICRALAGATSLAQLNLNLGVVSSPSRIKQLAEALRTNRSIQSLFLHGSPLTDAGLALLNPALALHPALVALDLGDCMLGDEAINLICGLLPPDGAKSGLKELTLSANPGITPKGWSRLAIAVAHSSQVRVLNLDYNPLGDHVAGMLAVAVASSRTLEVLDLEGTGLTNQSAQTLLDMVENYPTALRSLVLAENSISPELQQQICDLLSEGEEEEEVAGGAGDTQEWERGREPAAHQRGSSSWMCPSDPSSQMVLMTSGLG--DSLLAETEM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B2J9-1", "uniprot_id": "A0A8M2B2J9_DANRE", "id": "A0A8M2B2J9-1", "name": "", "aln": "MLPGSIQITGEALSGAEIKDICDSLKENSVRLLSVRGCQLSDRDFGRVCRGVAESHSLAQLNLNLGVVSTIGRTKQLADALKANRSIQTLFLHGSPLLDAGLVTLNTALSTHPSLVSLDLGDCMLGDEAIRLLCGLLPPDGAKSGLKELTLSANPAISSQGWARLAIAAAHSSQLRVLNLDYNPLGDHIAGMLAVAVASSRTLEVLDLEGTGLTNQSAQIFLDMVENYPTCLRVLVLAENDISPELQQQISDLLSEGDEEEDKDGEARGSSVTAREKPAWLPHSISASKRLGQKGSTDIHIPPHAFFRRDHLLLMK--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.****:**.*****::*** .*::*:*****:***:*.******:**.:* : *************: .* ****:**::*****:******** ****. **.**: **:**:*************.*:**********************.*:.:**:*****.*****:*************:****************************** :*********.** ******.*********.******:***: * * .:. * : . : .:* .. .::: : . .: * ** . ", "identical_positions": 216, "similar_positions": 62, "identity": "67.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111123-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F6Q5G6-1", "uniprot_id": "F6Q5G6_RAT", "id": "F6Q5G6-1", "name": "Aprataxin and PNK-like factor", "aln": "MSSEFFLHPLDGGPRVPVGPGQTVIGRGPLLGITDKRVSRRHAILEVVDSQLRIKPVHKNPCFHQSSEKSQLSPMETHVWSRLHPGDSFSLLLDKYAFRVSSTQSEVEVESTLRNSQMLDEDDILNEMRKSP-VVNLPDKAAGASQLQGSPEVTKTKCPPIDPMARDSSSGDCRAFSEHQPDPAHRKRILPAWMLAGSLSDQNLSTPAEGGGDKDAIQRDGKEGTHEDKTPVNTSWRGRKRFIPPGNSKSVSPKQDPGKKWRRSDQEGLAVSPEDVPESSSSITVSDPDMDIVKANKLSDTISAEELGEAPKHKAVTKPTTNDKDKTMSHPKCRAGVQSKTFLEKSQGCHPESSSAPSSPGASHTDTADSVLGCSEESKVRRTSCMYGANCYRKNPLHFQHFSHPGDSDYGAVPVTDE-GVTGDRPECPYGASCYRKNPQHRMEYRH-----SALPARVAVDEDDDDVGQPSDS-------DKDEEDYAPTDEDSDWQPGKDDEEKEDVDELLKEAKRFMRRKT-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D842-1", "uniprot_id": "APLF_MOUSE", "id": "Q9D842-1", "name": "Aprataxin and PNK-like factor", "aln": "MPSDFFLQPLDGGPRVPVGPGQTVIGRGPLLGITDKRVSRRHAILEVVDSQLRIKPIHRNPCFYQSSEKSQHSPMETQVWSQLHPGDSFSLLLDKYAFRVFSAESEVEMECTLRNSQMLDEDDILSEMQKSP-VVNLPDKTTGASQLQGSPEITKTKCPTIDPMS---SSGECRAFSEHQPRPTQRKRILPAWMLAESLSDQSLSTPAEGG-DKDVIQRSGKAGTCEDRTPGNTSWHGKKRLSPSGNSKSVSAEQDPGKKCRKADQEGPGVSSENVPESSSSNIVKDPDVDIVKTNKQKDGILIEELGEVSKHKAATKPTTNEEGESCAR------VQSKSPPEKSQGCHPESSSAPSSPDALHTDTADPVLGCSEESKVRRTACMYGANCYRRNPLHFQHFSHPGDSDYGEVHGTDE-GVIGDRPECPYGASCYRKNPQHKMEYRH-----SALPARVALDEDDDDVGQPSD--------DEDEEDYEPTDEDSDWHPGKDDEEQEDVDELLKEAKSSLHLKH-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IW19-1", "uniprot_id": "APLF_HUMAN", "id": "Q8IW19-1", "name": "Aprataxin and PNK-like factor", "aln": "MSGGFELQPRDGGPRVALAPGETVIGRGPLLGITDKRVSRRHAILEVAGGQLRIKPIHTNPCFYQSSEKSQLLPLKPNLWCYLNPGDSFSLLVDKYIFRILSIPSEVEMQCTLRNSQVLDEDNILNETPKSP-VINLPHETTGASQLEGSTEIAKTQMTPTNSVS---FLGENRDCNKQQPILAERKRILPTWMLAEHLSDQNLSVPAISG--GNVIQGSGKEEICKDKSQLNTTQQGRRQLISSGSSENTSAEQDTGEECKNTDQEESTISSKEMPQSFSAITLSNTEMNNIKTNAQRNKLPIEELGKVSKHKIATKRTPHKEDEAMSCSENCSSAQGDSLQDESQGSHSESSSNPSNPETLHAKATDSVLQGSEGNKVKRTSCMYGANCYRKNPVHFQHFSHPGDSDYGGVQIVGQ-DETDDRPECPYGPSCYRKNPQHKIEYRH-----NTLPVRNVLDEDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSDWEPGKEDEEKEDVEELLKEAKRFMKRK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AL87-1", "uniprot_id": "A0A8M3AL87_DANRE", "id": "A0A8M3AL87-1", "name": "", "aln": "-MPGFELEQVDGGSPVDLPYGETVLGRGPFLGVNDKRVSRNHGILENQNGVLRLKPTHLNPCFIQTNIVAPPQPLEKDQWHCLKDGDIFSLMPGKYIYRVHIKEDDQTPRNSQAFGEDVEVEKCLSEDTLEASSCTHSNLRHTHAEDEGAAGSSHTLASLNEPPS---------KSQQDKSSLPLRKRVLPAWMTTSAATSPSPAKVAKGT--------PTKAKRVATPKRATGPKRARTAAMSSEEEELEDKTPKRKTKRLKSDSEEESLPPLDDATAPSGESSVPDGVNGTGVMERND-----EERKGGGRRAQVRPGDQAQNS-----------------KTQTEDRSDSQVSRGLSQRSDVTESEIKTSRSEVKKPRRTACPYGSSCYRKNPLHFQECSHPGDIDYEEEKADEEENEDDDRPECPYGTQCYRKNPLHKKEYKH-----TKSPPKNTAAAAAADEDEDQYEN----SFINDESEEEEVDEDSDYVPESDGSGKEDIKRLQREAKNFLRRKK-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8JR14-1", "uniprot_id": "APLF_DROME", "id": "A8JR14-1", "name": "Aprataxin and PNK-like factor", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSATDASTADSGAKRKSSEDITHNCNANFGAENGLRKRVKSEEPVASIKDETNPEVPMKIKAEPVENADEPTS------------TTPAIKIKAEPADN-------------------------GNSPAAAMVKTEP--TNSNAQDAADESTVSSSSIRTSCRFGIRCYRRNPAHRSAEAHPGDQDYRRPNFPAP---PLGTPACPFGNACYRRNPVHFQDYSHPADFNSAQNIRNRLRQRRAQRQNDDDSG----TDEEDEPFGGDNDRDADYRPGADINEDED-DELEFDSQPISGDDYD", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : : . . : . : .::. : . . : .. : . : . . : : .. **:* :* ***:** * . :**** ** . * **:* ***:** * :* * . : : : . .:* *.*:*: * : . .** ..* ::: . ", "identical_positions": 36, "similar_positions": 55, "identity": "6.86%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111123-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BQ61-1", "uniprot_id": "TRIR_HUMAN", "id": "Q9BQ61-1", "name": "Telomerase RNA component-interacting RNase", "aln": "MAARGRRAEPQGREAPGPAGGGGGGSRWAESGSGTSPESGDEEVSGAGSSPVSGG---VNLFANDGSFLELFKRKMEEEQ-RQRQEEPPPGPQRPDQ-SAAAAGPGDPKRKGGPGSTLSFVGKRRGGNKLALKTGIVAKKQKTEDEVLTSKGDAWAKYMAEVKKYKAHQCGDDDKTRPLVK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D735-1", "uniprot_id": "TRIR_MOUSE", "id": "Q9D735-1", "name": "Telomerase RNA component-interacting RNase", "aln": "MAARGRRAEPPGREAPGPAGSG--RSRWAESGPGTSPESGDDEVS--GSSPVSSG---VNLFANDGSFLELFKRKMEEEQ-RQRQEEPPPGPQRPDPPASAAAGPGNPKRKGGPGPTLSFVGKRRGGNKLALKTGIVAKKQKTEDEVLTSKGDAWAKYMAEVKKYKAHQCGDDDKTRPLVK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IP71-1", "uniprot_id": "A0A0R4IP71_DANRE", "id": "A0A0R4IP71-1", "name": "", "aln": "MEKKQSKSDKHHRHHHHHHHHHQKHRHHHQTSSSSSDESG-------GSSPAHSAPKAANAFANDGSFMEMFKKKMEEEEKRKKQQQQEEEEEMMKGSSSAAQAPQDKK----AFSASSFVGKRRGGARLALKTGVVAKKQKQDSEAETGKGDAWTKYMAEVKKYKAHQCGDDDKTRPLVK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : ::: *. : ::...:* *** ****. .. .* *******:*:**:*****: *::*:: : . ::** .* : * . .: ********* :******:****** :.*. *.*****:*************************", "identical_positions": 85, "similar_positions": 40, "identity": "46.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111128-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70392-1", "uniprot_id": "RGRF2_MOUSE", "id": "P70392-1", "name": "Ras-specific guanine nucleotide-releasing factor 2", "aln": "-------------MQKSVRYNEGHALYLAMLARKEGTKRGFLSKKAAEASRWHEKWFALYQNVLFYFEGEQSGRPAGMYLLEGCSCERTPAPPRTNAGPAGARDALDKQYYFTVLFGHDGQKPLELRC--------------------------------------EEEQAGKEWMEAIHQASYADILIEREVLMQKYIHLVQIVETEKIATNQLRHQLED---QDTEIERLKSEIVALNKTKERMRP------------YHVHQEEEDPDIKKIKKVQSFMRGWLCRRKWKTIVQDYICSPHAESMRKRNQIVFTMVEAETEYVH-QLYILVNGFLRPLRMAASSKKPPINHDDVSSIFLNSETIMFLHEIFHQGLKARLANWP--------TLVLADLFDILLPMLNIYQEFVRNHQYSLQVLANCKQNRDFDKLLKQYEANPACEGRMLETFLTYPMFQIPRYIITLHELLAHTPHEHVERKSLEFAKSKLEELSRVMHDEVSDTENIRKNLAIERMIVEGCDILLDTSQTFIRQGSLIQVPSVERGKLSKVRLGSLSLKKEGERQCFLFTKHFLICTRSSGGK-----------LHLLKTGGVLSLIQCTLIEEPDGSDDDPKGSGHMFGHLDFKIVVEPPDAA-----------SFTVVLLAPSRQEKAAWMSDISQCVDNIRCN---------GLMTIVFEENS-----KVTVPHMIKSDARLHKDDTDICFSKTLN-----SCKVPQIRYASVERLLERLTDLRFLSIDFLNTFLHTYRIFTTATVVLAKLSDIYKRPFTSIPVR-------------------------------SLELFFATSQNNR-EHLVDG---KSPRLCRKFSSPPPLAVS-RTSSPVRARKLSLTSSLNSRIGALDLTNSSS---SSSPTTTTHSPAASPPPHT-------------------------------------------AVLESAPADKAG-------DSADMSPCRSP-------------TTPRHLRYRQPGGQVADSAHCSVSPASAFAIATAAAGHGSPPGFNN-ERTCDKEFIIRRTATNRVLNVLRHWVSKHAQDFELNNELKMNVLNLLEEVLRDPDLLPQERKATANILRALSQDDQD----------------DIHLKLEDIIQMT--------------DCPKAECFETLSAMELAEQITLLDHIVFRSIPYEEFLGQGWMKLD-----------KNERTPYIMKTSQHFNEMSNLVASQIMNYADISSRANAIEKWVAVADICRCLHNYNGVLEITSALNRSAIYRLKKTWAKVSKQTKALMDKLQKTVSSEGRFKNLRETLKNCNP--PAVPYLGMYLTDLAFIEEGTPNFTEEGLVNFSKMRMISHIIREIRQFQQTAYRIDQQPKVIQYLLDKALVIDEDSLYELSLKIEPRLPA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99JE4-1", "uniprot_id": "RGRF2_RAT", "id": "Q99JE4-1", "name": "Ras-specific guanine nucleotide-releasing factor 2", "aln": "-------------MQKSVRYNEGHALYLAFLARKEGTKRGFLSKKAAEASRWHEKWFALYQNVLFYFEGEQSGRPAGMYLLEGCSCERTPAPPRTNAGPAGARDALDKQYYFTVLFGHEGQKPLELRC--------------------------------------EEEQAGKEWMEAIHQASYADILIEREVLMQKYIHLVQIVETEKIAANQLRHQLED---QDTEIERLKSEIVALNKTKERMRP------------YHTHQEEEDPDIKKIKKVQSFMRGWLCRRKWKTIVQDYICSPHAESMRKRNQIVFTMVEAESEYVH-QLYILVNGFLRPLRMAASSKKPPISHDDVSSIFLNSETIMFLHEIFHQGLKARLANWP--------TLVLADLFDILLPMLNIYQEFVRNHQYSLQVLANCKQNRDFDKLLKQYEGNPACEGRMLETFLTYPMFQIPRYIITLHELLAHTPHEHVERKSLEFAKSKLEELSRVMHDEVSDTENIRKNLAIERMIVEGCDILLDTSQTFIRQGSLIQVPSVERGKLSKVRLGSLSLKKEGERQCFLFTKHFLICTRSSGGK-----------LHLLKTGGVLSLIQCTLIEEPDTSDDDTKGPGHMFGHLDFKIVVEPPDAA-----------PFTVVLLAPSRQEKAAWMSDISQCVDNIRCN---------GLMTIVFEENS-----KVTVPHMIKSDARLHKDDTDICFSKTLN-----SCKVPQIRYASVERLLERLTDLRFLSIDFLNTFLHTYRIFTTAAVVLGKLSDIYKRPFTSIPVR-------------------------------SLELFFATSQNNR-EHLVDG---KSPRLCRKFSSPPPLAVS-RTSSPVRARKLSLTSSLNSRIGALDLTTSSS---SSSPTTTVHSPAASPPPHT-------------------------------------------AVPESAPADRAG-------DSTDMSPCRSPS------------TTPRHLRYRQPGGQVADSTHCAVSPASAFAIATAAAGHGSPPGFNN-ERTCDKEFIIRRTATNRVLNVLRHWVSKHSQDFELNNELKMNVLNLLEEVLRDPDLLPQERKATANILRALSQDDQD----------------DIHLKLEDIIQMT--------------DCPKAECFETLSAMELAEQITLLDHIVFRSIPYEEFLGQGWMKLD-----------KNERTPYIMKTSQHFNEMSNLVASQIMNYADISSRANAIEKWVAVADICRCLHNYNGVLEITSALNRSAIYRLKKTWTKVSKQTKALMDKLQKTVSSEGRFKNLRETLKNCNP--PAVPYLGMYLTDLAFIEEGTPNFTEEGLVNFSKMRMISHIIREIRQFQQTAYRIDQQPKVIQYLLDKALVIDEDTLYELSLKIEPRLPA--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14827-1", "uniprot_id": "RGRF2_HUMAN", "id": "O14827-1", "name": "Ras-specific guanine nucleotide-releasing factor 2", "aln": "-------------MQKSVRYNEGHALYLAFLARKEGTKRGFLSKKTAEASRWHEKWFALYQNVLFYFEGEQSCRPAGMYLLEGCSCERTPAPPRAGAGQGGVRDALDKQYYFTVLFGHEGQKPLELRC--------------------------------------EEEQDGKEWMEAIHQASYADILIEREVLMQKYIHLVQIVETEKIAANQLRHQLED---QDTEIERLKSEIIALNKTKERMRP------------YQSNQEDEDPDIKKIKKVQSFMRGWLCRRKWKTIVQDYICSPHAESMRKRNQIVFTMVEAESEYVH-QLYILVNGFLRPLRMAASSKKPPISHDDVSSIFLNSETIMFLHEIFHQGLKARIANWP--------TLILADLFDILLPMLNIYQEFVRNHQYSLQVLANCKQNRDFDKLLKQYEANPACEGRMLETFLTYPMFQIPRYIITLHELLAHTPHEHVERKSLEFAKSKLEELSRVMHDEVSDTENIRKNLAIERMIVEGCDILLDTSQTFIRQGSLIQVPSVERGKLSKVRLGSLSLKKEGERQCFLFTKHFLICTRSSGGK-----------LHLLKTGGVLSLIDCTLIEEPDASDDDSKGSGQVFGHLDFKIVVEPPDAA-----------AFTVVLLAPSRQEKAAWMSDISQCVDNIRCN---------GLMTIVFEENS-----KVTVPHMIKSDARLHKDDTDICFSKTLN-----SCKVPQIRYASVERLLERLTDLRFLSIDFLNTFLHTYRIFTTAAVVLGKLSDIYKRPFTSIPVR-------------------------------SLELFFATSQNNRGEHLVDG---KSPRLCRKFSSPPPLAVS-RTSSPVRARKLSLTSPLNSKIGALDLTTS------SSPTTTTQSPAASPPPHTGQIPLDLSRGLSSPEQSPGTVEENVDNPRVDLCN-KLKRSIQKAVLESAPADRAGVESSPAADTTELSPCRSP-------------STPRHLRYRQPGGQTADNAHCSVSPASAFAIATAAAGHGSPPGFNNTERTCDKEFIIRRTATNRVLNVLRHWVSKHAQDFELNNELKMNVLNLLEEVLRDPDLLPQERKAAANILRALSQDDQD----------------DIHLKLEDIIQMT--------------DCMKAECFESLSAMELAEQITLLDHVIFRSIPYEEFLGQGWMKLD-----------KNERTPYIMKTSQHFNDMSNLVASQIMNYADVSSRANAIEKWVAVADICRCLHNYNGVLEITSALNRSAIYRLKKTWAKVSKQTKALMDKLQKTVSSEGRFKNLRETLKNCNP--PAVPYLGMYLTDLAFIEEGTPNFTEEGLVNFSKMRMISHIIREIRQFQQTSYRIDHQPKVAQYLLDKDLIIDEDTLYELSLKIEPRLPA--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B5Z6-1", "uniprot_id": "A0A8M3B5Z6_DANRE", "id": "A0A8M3B5Z6-1", "name": "", "aln": "-------------MQKSVRYNEGHALYLSMVARKEGIKRGHLSKKAAENNRWNEKYFALYQNVLFYFENEQSTRPSGIYLLEGSTCERIPAPKVSTVGK---ESSDKQQHYFLVIFGHDGQKPLELRS--------------------------------------EEEADCNEWVEVIQQASYSDLIIEREVLMQKYIHLVQIMETEKVAANQLRTQLED---QDTEIERLKAEIVVLNKSKERMLP------------FQSFQDEEDPDIKKIKMVQSFMRGWLCRRKWKIIVQDYICSPHAESMRKRNQIVFNMVEAETEYVL-QLSILVNCFLRPLRMAASSKKPPISHDDVSSIFLNSETIMFLHEIFHQGLKARIANWP--------TLVLADLFDILLPMLNIYQEFVRNHQYSLQVLANCKQNRDFDKLLKQYEANAACEGRMLETFLTYPMFQIPRYIITLHELLAHTPHEHVERKSLEFAKSKLEELSKMMHDEVSDTENIRKNLAIERMIVEGCDILLDTSQTFVRQGSLIQLPSVEKGKLSKVRLGSLTLRKEAERQCFLFTKHFLICTRTSGGK-----------LHLLKQGGTLSLIECTLIEELDTSDEDYNAAGQGLNHLEFKIVVEPADGS-----------SFSVVLLAPSRQEKAAWTSDISQCIDNIRCN---------GLMNSVFEDNS-----KVTVPHMIKSDARLHKDDVDICFSKTLN-----SCKVPQIRYASVERLLERLTDLRFLSIDFLNTFLHTYRIFTTAAVVMDKLADIYKKPFTSIPVRVQYHSSDRLSITSICPDYSLKITRLALDQSKSLELFFATNQGPWSGEHLNN---KSPRLSRKFSSPPPISITSRTSSPIHSRKLSLSSPVSCKAGALDLSTSTFS-AASSPTSPYNPIICSPPPTCTKAPLDLSRGPSSPELCPSTPEEGGELPRIDAFCGKLRRSIRRAVLESVSLDKFIPETPTSSDSGEMSPSRSP-------------STPRHLRYRQPAGQCPDNSRCAVSPASAFAIATAAAGHSSPQGFTNPEKSYDKEFLIRRAATNRVLNVLRHWVSKHSQDFEMNAELTTAVMALLEEVLRDPDLLPQERKAAVNILSALSQEEQD----------------DSQLKIEDIVQMV--------------DCPRAECFESLSAMELAEQITLLDHIVFRNIPYEEFLGQGWMKMD-----------KNERTPYIMKTSQHFNDMSNLVASEIMAHADVSSRAGSIDKWLAVADICRCLNNYNGVLEITSALNRSAIYRLKKTWAKVCKQTKALMDRLQKIVSSEGRFKNLRETLKNCNP--PCVPYLGMYLTDLAFIEEGTPNFTEEGLVNFSKMRMISHIIREIRQFQQAPYRIELQPKVTQFLLDKTLVMDEDTLYELSLKIEPRLPPAN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P07866-1", "uniprot_id": "LTE1_YEAST", "id": "P07866-1", "name": "Guanine nucleotide exchange factor LTE1", "aln": "MEIFSQKDYYPTPSSNVISYESDCVSKPVNSADLPALIVHLSSPLEGVDYNASADFFLIYRNFITPQDLHDLLIYRFRWCIREITTNAAKAKRRRIGEVALVRTFVLLRHSILNYFVQDFLPNITLRLRLIEFLNDKHIEQYPKIISSCIINLKKNWVHCSKLVWENIELNEPDKLDFDAWLHYSLKDFTQLESLHKRGSRLSIYARQSFASPDFRNQSVLSLYKTSDVFRLPEKLQSSNSSKNQRSPSMLLFPDNTSNVYSKHRIAKEPSVDNESEDMSDSKQKISHLSKVTLVSTLMKGVDYPSSYAVDKIMPPTPAKKVEFILNSLYIPEDLNEQSGTLQGTSTTSSLDNNSNSNSRSNTSSMSVLHRSAIGLLAKWMKNHNRHDSSNDKKFMSAIKPANQKPEMDAFVKYVVSISSLNRKSSKEEEEEFLNSDSSKFDILSARTIDEVESLLHLQNQLIEKVQTHSNNNRGPTVNVDCERREHIHDIKILQQNSFKPSNDNFSAMDNLDLYQTVSSIAQSVISLTNTLNKQLQNNESNMQPSPSYDALQRRKVKSLTTAYYNKMHGSYSAESMRLFDKDNSSSRTDENGPQRLLFHETDKTNSEAITNMTPRRKNHSQSQKSMTSSPLKNVLPDLKESSPLNDSREDTESITYSYDSELSSSSPPRDTVTKKSRKVRNIVNNTDSPTLKTKTGFLNLREFTFEDTKSLDEKKSTIDGLEKNYDNKENQESEYESTKKLDNSLDASSEANNYDITTRKKHSSCNHKIKQAVVRPASGRISISRVQSIAITPTKELSIVDPEQNKSNSVIEEISEIEPLN---------LEYNKKSALYSDTSSTVISISTSKLFESAQNSPLKQTQNPQREFPNGTSVSETNRIRLSIAPTIESVVSDLNSITTGSTVETFETSRDLPVPHQRIINLREEYQRGNQDIISNTSSLHELKTIDLSDSNNDLESPSTHAKNNKYFFSPDDGSIDVASPMKNVEELKSKFLKNESETNSNISGSVLTMDDIDINDTSSARNTRRANSESAFTGSLNKKNLNEIANMLDDSINDDPITVALMKLEGTYEKIPEKPENTKSSDAIGIKTSKLADEVEMLNLNNLPSFQNSPAEKRKSLLIERRRQTIMNIPFTPDQSEKEGFTSSSPEKIDVSANVDVAVQAAQIQELIGQYRIHDSRLMISNNESHVPFILMYDSLSVAQQMTLIEKEILGEIDWKDLLDLKMKHEGPQVISWLQLLVRNETLSGIDLAISRFNLTVDWIISEILLTKSSKMKRNVIQRFIHVADHCRTFQNFNTLMEIILALSSSVVQKFTDAWRLIEPGDLLTWEELKKIPSLDRNYSTIRNLLNSVNPLVGCVPFIVVYLSDLSANAEKKDWILEDKVVNYNKFDTNVQIVKNF--IQRVQWSKFYTFKVNHELLSKCVYISTLTQEEINELST-------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : *:.. . * . * . . .:* :*:*.: : .: : :. : : * . :: : * :: : ** : * : :: *: : : ::* :.* :..*: ::* * : ::: ** :: *.:*:: * : : ::*.:.: . * : :.: . :*. : . . * ::*: : *:: .* * : :. : .:*....:.::. *. *:.:: .**. * : * .:: * * :: : ::* . . : :: :::. ::. .::: .* :*::* * : :: . * : . **:. . . *:: * :: .: : . *.:. * :* :. :::.. ** . . *.: :: **: : : :: : : : .... :* . . :: : * .: . ..:. .. . * .* : : : :*.*: : .: : ::* . .* .**:.. * *: : *. . .::: : :*.*: *.:. : :: :: . .:: : . : *: : * . :*: : . .* .* : . .:: . . :. :: . *:*.. ..:: : * .: . *: * :.. . : . . * . . : .. : . : .. . *. . *:. .: . . . . :* : :..* . : * : .:. ..: :.: .** :::.*: . : *.. *: :.*:: ** : .*.::: * :: :* :: : :. : .::.:*:*:**::: :: .* ::::*. : . :** . * : .:** : : *:*: . . : . *:::: *** ** ::*:* ::** **. *.: ::..:* : :.*:* * : .:..:*: *:. ** .**:: :**:**: * . : *: :**:.*: :*:::: :*:. : ** : **.* : :. : *:. ", "identical_positions": 153, "similar_positions": 445, "identity": "10.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111129-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28867-1", "uniprot_id": "KPCD_MOUSE", "id": "P28867-1", "name": "Protein kinase C delta type", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPFLRISFNSYELGSLQVEDEASQPFCAVKMKEALSTERGKT---------------------------LVQKKPTMYPEWKTTFDAHIYEGRVIQIVLMRAAED---------------------------------------------PVSEVTVGVSVLAERCKKNNGKAEFWLDLQPQAKVLMCVQYFLEDG-------DCKQSMRSEEEAKFPTMNRR-GAIKQAKIHYIKN-HEFIATFFGQPTFCSVCKEFVWGLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTATNSRDTIFQKERFNIDMPHRFKVYNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCGINQKLLAEALNQVTQRSSR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KLD--TTESVGIYQGFEKKPEVSGSDILDNNGTYGKIWEGS-----------TRCTLENFTFQKVLGKGSFGKVLLAELKGKDKYFAIKCLKKDVVLIDDDVECTMVEKRVLALAWES--PFLTHLICTFQTKDHLFFVMEFLNGGDLMFHIQDKGRFELYRATFYAAEIICGLQFLHSKGIIYRDLKLDNVMLDRDGHIKIADFGMCKENIFGEGRASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDIMEKLFERDPDKRLG----VTGNIRIHPFFKTINWSLLEKRKVEPPFKPKVKSPSDYSNFDPEFLNEKPQLSFSDKNLIDSMDQEAFHGFSFVNPKFEQFLDI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09215-1", "uniprot_id": "KPCD_RAT", "id": "P09215-1", "name": "Protein kinase C delta type", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPFLRISFNSYELGSLQAEDDASQPFCAVKMKEALTTDRGKT---------------------------LVQKKPTMYPEWKSTFDAHIYEGRVIQIVLMRAAED---------------------------------------------PMSEVTVGVSVLAERCKKNNGKAEFWLDLQPQAKVLMCVQYFLEDG-------DCKQSMRSEEEAMFPTMNRR-GAIKQAKIHYIKN-HEFIATFFGQPTFCSVCKEFVWGLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTATNSRDTIFQKERFNIDMPHRFKVYNYMSPTFCDHCGTLLWGLVKQGLKCEDCGMNVHHKCREKVANLCGINQKLLAEALNQVTQKASR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KPE--TPETVGIYQGFEKKTAVSGNDIPDNNGTYGKIWEGS-----------NRCRLENFTFQKVLGKGSFGKVLLAELKGKERYFAIKYLKKDVVLIDDDVECTMVEKRVLALAWEN--PFLTHLICTFQTKDHLFFVMEFLNGGDLMFHIQDKGRFELYRATFYAAEIICGLQFLHGKGIIYRDLKLDNVMLDKDGHIKIADFGMCKENIFGENRASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDIMEKLFERDPAKRLG----VTGNIRLHPFFKTINWNLLEKRKVEPPFKPKVKSPSDYSNFDPEFLNEKPQLSFSDKNLIDSMDQTAFKGFSFVNPKYEQFLE-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q05655-1", "uniprot_id": "KPCD_HUMAN", "id": "Q05655-1", "name": "Protein kinase C delta type", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPFLRIAFNSYELGSLQAEDEANQPFCAVKMKEALSTERGKT---------------------------LVQKKPTMYPEWKSTFDAHIYEGRVIQIVLMRAAEE---------------------------------------------PVSEVTVGVSVLAERCKKNNGKAEFWLDLQPQAKVLMSVQYFLEDV-------DCKQSMRSEDEAKFPTMNRR-GAIKQAKIHYIKN-HEFIATFFGQPTFCSVCKDFVWGLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTAANSRDTIFQKERFNIDMPHRFKVHNYMSPTFCDHCGSLLWGLVKQGLKCEDCGMNVHHKCREKVANLCGINQKLLAEALNQVTQRASR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSDSASSEPVGIYQGFEKKTGVAGEDMQDNSGTYGKIWEGS-----------SKCNINNFIFHKVLGKGSFGKVLLGELKGRGEYFAIKALKKDVVLIDDDVECTMVEKRVLTLAAEN--PFLTHLICTFQTKDHLFFVMEFLNGGDLMYHIQDKGRFELYRATFYAAEIMCGLQFLHSKGIIYRDLKLDNVLLDRDGHIKIADFGMCKENIFGESRASTFCGTPDYIAPEILQGLKYTFSVDWWSFGVLLYEMLIGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDILEKLFEREPTKRLG----VTGNIKIHPFFKTINWTLLEKRRLEPPFRPKVKSPRDYSNFDQEFLNEKARLSYSDKNLIDSMDQSAFAGFSFVNPKFEHLLED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QDJ7-1", "uniprot_id": "A0A8M9QDJ7_DANRE", "id": "A0A8M9QDJ7-1", "name": "Protein kinase C delta type", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAPFLRIAFNEFNLG--ELPPMTEQPFCAIKMKESLSTERGKT---------------------------LVQRKPTMYPAWKSTFDAHIYEGRVIQVVLMKTAEE---------------------------------------------ALSEATVGVSVIAERCKKGNGHAEFWVDLQPSGKVMMSVQFFVEDTD-----LDSKASMTAKDDDGILTINRRRGAIKQAKVHFIKN-HEFTATFFKQPTFCSVCREFVWGLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTATNSRDTMFQKERFKIDMPHRFKTNNYMSPTFCDHCGSLLWGMVKQGLKCEDCGMNVHHKCQTKVANLCGINQKLLAEALNQVSLKSST---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KRPDPTLSEIGIYQAIDKN---VPADPSAEGSQYGKFWDITPAVPASTIVSTVRVSLNDFVFQKVLGKGSFGKVMLAELKGKGQYFAIKALKKDVVLMDDDVECTMVEKRVLALAWEN--PFLTHLYCTFQSKEHLFFVMEYLNGGDLMFHIQDKGRFDLYRATFYAAEIICGLQYLHSKGIVYRDLKLDNVMLDKDGHIKIADFGMCKENMIGENRATTFCGTPDYIAPEILLGQKYSFSVDWWSFGVLLYEMLIGQSPFQGDDEDELFDSIRMDVPHYPRWITKEAKDLLEKLFERDPTRRLG----VVGNIRGHAFFKTINWPALEKREVSPPFKPKVKSSSDCSNFDREFLSEKPRLSQSDKNLIDSMDQTAFAGFSFINPKMESLIDK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P83099-1", "uniprot_id": "KPC4_DROME", "id": "P83099-1", "name": "Putative protein kinase C delta type homolog", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMFTRAQVRKQKTSNSSSQRPRSSGGSTRHETRYKQSSTSSSGAGSG---------------------------LSGASGASGARRDQYRDRDHYGKHSFELPRQHSKEE---------------------------------------------AYHRDRESSAGGVDRGERSG--------IGGNGGGVTGGGVYVDRR-------TRPRSIT----------NRR-GAIKHQKTHDING-HRFVAKFFRQPTFCAFCNLFLWGFGKQGYQCIICQTVVHKKCHDKLLGKCSGSVFTSASTILLRERFKIDMPHRFKPHTFMSPTFCDHCGSLMGGFFIQGLKCEECDVNCHKKCERLTANLCGVNQKLIVEALNHVKRGARE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ARDSPSTPPS-LNPAYKIEASEEHDETSYTYSQFQKSGRFTAP--ATVIPRFKNYSVDDFHFLAVLGKGSFGKVLLAELRDTTYYYAIKCLKKDVVLEDDDVDSTLIERKVLALGTKH--PYLCHLFCTFQTESHLFFVMEYLNGGDLMFHIQESGRFSEERARFYGAEIISGLKFLHKKGIIYRDLKLDNVLLDYEGHVRIADFGMCKLQIYLDKTADSFCGTPDYMAPEIIKGEKYNQNVDWWSFGVLLYEMLIGQSPFSGCDEDELFWSICNEIPWFPVYISAEATGILKGLLEKDYTKRIGSQYSPAGDIADHIFFRPIDWGLLEKRQIEPPFKPQVKHPLDTQYFDRVFTRERVRLTPIDKEILASMDQKQFHGFTYTNPHIT--LD-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P24583-1", "uniprot_id": "KPC1_YEAST", "id": "P24583-1", "name": "Protein kinase C-like 1", "aln": "MSFSQLEQNIKKKIAVEENIIRGASALKKKTSNVMVIQKCNTNIREARQNLEYLEDSLKKLRLKTAQQSQGENGSEDNERCNSKEYGFLSTKSPNEHIFSRLDLVKYDCPSLAQRIQYMLQQLEFKLQVEKQYQEANTKLTKLYQIDGDQRSSSAAEGGAMESKYRIQMLNKALKKYQAINVDFDQFKHQPNDIMDNQQPKFRRKQLTGVLTIGITAARDVDHIQSPMFARKPESYVTIKIDDTIKARTKPSRNDRWSEDFQIPVEKGNEIEITVYDKVNDSLIPVAIMWLLLSDIAEEIRKKKAGQTNEQQGWVNASNINGGSSLASEEGSTLTSTYSNSAIQSTSAKNVQGENTSTSQISTNSWFVLEPSGQILLTLGFHKSSQIERKQLMGGLHRHGAIINRKEEIFEQHGHHFVQKSFYNIMCCAYCGDFLR---YTGFQCQDCKFLCHKKCYTNVVTKCIAKTS--TDTDPDEAKLNHRIPHRFLPTSNRGTKWCCHCGYILPWGRHKVRKCSECGIMCHAQCAHLVPDFCGMSMEMANKILKTIQDTKRNQEKKKRTVPSAQLGSSIGTANGSDLSPSKLAERANAPLPPQPRKHDKTPSPQKVGRDSPTKQHDPIIDKRISLQTHGREKLNKFIDENEAYLNFTEGAQQTAEFSSPEKTLDPTSNRRSLGLTDLSIEHSQTWESKDDLMRDELELWKAQREEMELEIKQDSGEIQEDLEVDHIDLETKQKLDWENKNDFREADLTIDSTHTNPFRDMNSETFQIEQDHASKEVLQETVSLAPTSTHASRTTDQQSPQKSQTSTSAKHKKRAAKRRKVSLDNFVLLKVLGKGNFGKVILSKSKNTDRLCAIKVLKKDNIIQNHDIESARAEKKVFLLATKTKHPFLTNLYCSFQTENRIYFAMEFIGGGDLMWHVQNQ-RLSVRRAKFYAAEVLLALKYFHDNGVIYRDLKLENILLTPEGHIKIADYGLCKDEMWYGNRTSTFCGTPEFMAPEILKEQEYTKAVDWWAFGVLLYQMLLCQSPFSGDDEDEVFNAILTDEPLYPIDMAGEIVQIFQGLLTKDPEKRLGAGPRDADEVMEEPFFRNINFDDILNLRVKPPYIPEIKSPEDTSYFEQEFTSAPPTLTPLP-SVLTTSQQEEFRGFSFMPDDLDL----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. . : . : . : . : . ::: :: . . : : :. . :: * :*: . *:: : : *.* . * : *: * *: *::* *: **** ::: :* ... .* . ::: :**** . ...:* *** :: : **.:*.: * :* ..::**:. :: : *: : : . . * : . :::* : *****.****:*.: :. *** **** :: :.*::.: *::*: *. : *:* :* *:**::.:::*.**::.*****:*:*:. *:. ** **.**:: .*:::* :*::******:*::* :**::***:*:** :: : :*****:::****: :*. ****:******:**: **** * ****:* :* : * :* :: * ::: *: :: :*:* ..:: . **: *:: : : .:.**: *::* . * . *: * *: .:: : :* * **:: . ", "identical_positions": 153, "similar_positions": 198, "identity": "13.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111129-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80XX4-1", "uniprot_id": "MSTN1_RAT", "id": "Q80XX4-1", "name": "Musculoskeletal embryonic nuclear protein 1", "aln": "MSEAGTPEAPIKKKRPPVKEEDLKGARGSLSKNQEIKSKTYQVMRDYEQAGSAAPSIFSRNRTGTETVFEKPKEGPAKSVFG-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99JI1-1", "uniprot_id": "MSTN1_MOUSE", "id": "Q99JI1-1", "name": "Musculoskeletal embryonic nuclear protein 1", "aln": "MSEAGTPEGPIKKKRPPVKEEDLKGARGTLAKNQDIKSKTYQVMRDYEQAGSAAPSVFSRNRTGTETVFEKPKEGPAKSVFG-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IVN3-1", "uniprot_id": "MSTN1_HUMAN", "id": "Q8IVN3-1", "name": "Musculoskeletal embryonic nuclear protein 1", "aln": "MSQAGAQEAPIKKKRPPVKDEDLKGARGNLTKNQEIKSKTYQVMRECEQAGSAAPSVFSRTRTGTETVFEKPKAGPTKSVFG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NX89-1", "uniprot_id": "A0A8M1NX89_DANRE", "id": "A0A8M1NX89-1", "name": "Musculoskeletal embryonic nuclear protein 1", "aln": "MSQPEVK----KKKRPVVKEEDLKGARSKLGLKGEVKSKTYEVMAECERMGKVAPSVFSGVRSGNETVIEKPKP-PSGSVFGK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:. . ***** **:*******..* : ::*****:** : *: *..***:** *:*.***:**** *: **** ", "identical_positions": 45, "similar_positions": 19, "identity": "54.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111129-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IVN3-1", "uniprot_id": "MSTN1_HUMAN", "id": "Q8IVN3-1", "name": "Musculoskeletal embryonic nuclear protein 1", "aln": "MSQAGAQEAPIKKKRPPVKDEDLKGARGNLTKNQEIKSKTYQVMRECEQAGSAAPSVFSRTRTGTETVFEKPKAGPTKSVFG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q99JI1-1", "uniprot_id": "MSTN1_MOUSE", "id": "Q99JI1-1", "name": "Musculoskeletal embryonic nuclear protein 1", "aln": "MSEAGTPEGPIKKKRPPVKEEDLKGARGTLAKNQDIKSKTYQVMRDYEQAGSAAPSVFSRNRTGTETVFEKPKEGPAKSVFG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F422-1", "uniprot_id": "E7F422_DANRE", "id": "E7F422-1", "name": "Musculoskeletal embryonic nuclear protein 1", "aln": "MSQLGEQE---EVKRPEVKTEDLIGARDKLASGTEVKSKTFEVMQECERAGKAAPSVFSNVRSGSETAFNKP----TKRK--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**: * * : *** ** *** ***..*:.. ::****::**:: *:**.*******. *:*:**.*:** :* ", "identical_positions": 40, "similar_positions": 21, "identity": "48.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111129-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O94876-1", "uniprot_id": "TMCC1_HUMAN", "id": "O94876-1", "name": "Transmembrane and coiled-coil domains protein 1", "aln": "-------------------MEPSGSEQLFEDPDPGGKSQDAEARKQTESEQKLSKMTHNALENINVIGQGLKHLFQHQRRRSSVSPHDVQQIQADPEPEMDLESQNACAEIDGVPTHPTALNRVLQQIRVPPKMKRGTSL-HSRRGKPEAPKGSPQINRKSGQEMTAVMQSGRPRSSSTTDAPTSSAMMEIACAAAAAAAACLPGEEGTAERIERLEVSSLAQTSSAVASSTDGSIHTDSVDGTPDPQRTKAAIAHLQQKILKLTEQIKIAQTARDDNVAEYLKLAN-SADKQQAARIKQVFEKKNQKSAQTILQLQKKLEHYHRKLREVE-----QNGIPRQPKDVFRDMHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSADNIPNLKDSLEEGQVDDAGKALG-VISNFQSSP----KYGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNTLDMQSSG-------------FDALLHEIQEIRETQARLEESFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLENATARNLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFSTLFLVVFIAFLWKHWDALFSYVERFFSS-PR--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q69ZZ6-1", "uniprot_id": "TMCC1_MOUSE", "id": "Q69ZZ6-1", "name": "Transmembrane and coiled-coil domains protein 1", "aln": "-------------------MEPSGSEQLYEDPDPGGKSQDAEARRQTESEQKLSKMTHNALENINVIGQGLKHLFQHQRRRSSVSPHDVQQIQTDPEPEVDLDSQNACAEIDGVSTHPTALNRVLQQIRVPPKMKRGTSL-HSRRGKSEAPKGSPQINRKSGQEVAAVIQSGRPRSSSTTDAPTSSSVMEIACAAG----VCVPGEEATAERIERLEVSSLAQTSSAVASSTDGSIHTESVDGIPDPQRTKAAIAHLQQKILKLTEQIKIAQTARDDNVAEYLKLAN-SADKQQAARIKQVFEKKNQKSAQTILQLQKKLEHYHRKLREVE-----QNGIPRQPKDVFRDMHQGLKDVGAKVTGFSEGVVDSVKGGFSSFSQATHSAAGAVVSKPREIASLIRNKFGSADNIPNLKDSLEEGQVDDGGKALG-VISNFQSSP----KYGSEEDCSSATSGSVGANSTTGGIAVGASSSKTNTLDMQSSG-------------FDALLHEVQEIRETQARLEDSFETLKEHYQRDYSLIMQTLQEERYRCERLEEQLNDLTELHQNEILNLKQELASMEEKIAYQSYERARDIQEALEACQTRISKMELQQQQQQVVQLEGLENATARNLLGKLINILLAVMAVLLVFVSTVANCVVPLMKTRNRTFSTLFLVAFIAFLWKHWDALFSYVDRLFSP-PR--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3AVM2-1", "uniprot_id": "A0A8M3AVM2_DANRE", "id": "A0A8M3AVM2-1", "name": "", "aln": "-------------------------------------------------------------------------MFAG----SMISPMDVILNLITPDP-----------------------------------------------SPSTSPTG--TIERLEGAVAQATLAS--------------------------------FGADASLLSSEEVCVCVDPQRSRCVC---------------VDPQRTRQALAQLQQKILKLTEQLRIEQAARDDNVAEYLKLASNANDKQQSARIKQVFEKKNQKSAASIAQLQRKLEHCHRRLRDVE-----HSGVQRQPKDVLRDMQQNLRGV---MTGLSGGVVDSVRG---------------VASKPREIASLFRHRFGSADNISALRDGAEDVEDGATGRSLGSATARLQHSP----KFGSEDDCSSATSGSAEAHCGPG-APGGPPSSRG-----TGGG-------------LEVLLQEVQELQEVQAQLEEQLEELKSSCREECAVLMQTLQEDRFRCERLEEQVNDLTELHQNEILNLKQELASMEEKIAYQSNERARDLQEALEACQTRVSKMELQQQQQQVVQLEGLENATARTLLGKLMTVLLALMAVLLVLVSAVANCVLPLMKTRSRSVSSLLLVLLLAVLWRNWDSFSGHTHRFLQPLPR--------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E1JJ71-1", "uniprot_id": "E1JJ71_DROME", "id": "E1JJ71-1", "name": "", "aln": "MDTTPNAAPNPNQNRDFVTLKPLRPSRGSSSNLRASRSPSASRSTEQMSRERASEAAAATQTAAATAGGATAHSAGGTAGGSAAATTTAGGATSGSGTASANTNSNSSASSSTVAAAQAAVYSGGNTVTGSLGSAGVVARGFRSHSPTHRRRSRERQRRTHGSDQGGLLAYSGLVGVNDMTDFLGPQQGGGGGGGGGGGGGGGGGSAGTGSGLEDSRLSGNEDYYSSFVSDEFDS-SKKVHRRCHERSSSVQAIDRLNTKIQCTKESIRQEQTARDDNVNEYLKLAA-SADKQQLQRIKAVFEKKNQKSAHNISQLQKKLDNYTKRAKDLQNHQFQTKSQHRQPREVLRDVGQGLRNVGGNIRDGITGFSG------------------SVMSKPREFAHLIKNKFGSADNINQMSEAELQGMQSANADVLG--SERLQQVPGAGTSTGSGGGGQNNNTGGAGSGTGKFNSDNGSECSSVTSESIPGGSGKSQSGASQYHIVLKTLLTELAERKAENEKLKERIERLETG-QKEFNNLTATLESERYRAEGLEEQINDLTELHQNEIENLKQTIADMEEKVQYQSDERLRDVNEVLENCQTRISKMEHMSQQQ-YVTVEGIDNSNARALVVKLINVVLTILQVVLLLVATAAGIIMPFLKTRVRVLTTFLSICFVIFVIRQWPDVQDIGSGLVRHLKQSLVVK---------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O15482-1", "uniprot_id": "TEX28_HUMAN", "id": "O15482-1", "name": "Testis-specific protein TEX28", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------MVLKAEHTRSPSATLPSN-------------------------------VPSCRSLSSS-EDGPSGPSSLA--------------------DGGLAHNLQDSVRHRILYLSEQLRVEKASRDGNTVSYLKLVS-KADRHQVPHIQQAFEKVNQRASATIAQIEHRLHQCHQQLQELEEG--------CRPEGLLLMAESDPANCE----------------------------------PPSEKALLSEPPEPGGEDG-PVNLPHASRPFILESRFQS-----LQQGT-----CLETEDVAQQQN-----------------------------------------LLLQKVKAELEEAKRFHISLQESYHSLKERSLTDLQLLLESLQEEKCRQALMEEQVNGRLQGQLNEIYNLKHNLACSEERMAYLSYERAKEIWEITETFKSRISKLEMLQQVTQLEAAEHLQ-SRPPQMLFKFLSPRLSLATVLLVFVSTLCACPSSLISSRLCTCTMLMLIGLGVLAWQRWRAIPATDWQEWVPSRCRLYSKDSGPPADGP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1LWH7-1", "uniprot_id": "F1LWH7_RAT", "id": "F1LWH7-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------MQVESTKSSSATFPPN-------------------------------VPSYRSLSSSHEDCPSSHTSFS--------------------DGELARNVREGVKHRIFYLSEQLRVEKASRDENTMSYLKLIS-KADRHQAPHIRKAFERVNQRTSATIAHIERKLYQCHQQLKELEEG--------CSPTSLVLNVDSGMDSHK----------------------------------QPGGKILYSKLSKPDGEDSLPINVARSS---TLESHLPG-----MQQRK-----FSDKKYVAQQQK-----------------------------------------LLLQKMKEELTEAKKVHASLQLSHQNLKESHMIDVRRILESLQEKKTRQSLMEEHVNDHLQRYLDEICHLKQHLACTEEKMAYLSYERAKEIWDVMETFKNRITKLETLQQATQLEMMASLR-TRPKDFFFRFISLLLTLTTILLVVVSTLCSCPLPLLNSRLRIFIVFMIIGLGTLAWQKRHVISIIDWQAWVPFKWRSDLKDAKPPSARH", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : : . . : : :. :* .*.:: :::** *. .**** *::* :*: .**: **::: .* :::::* : :: :::: * :. .. . * . ..:: : . . . :* . . . :. : *: * : : *: . *: : : :*:..: * :**::*. : :** :**: :* **:: * * ** ::: : * :.*::*:* .* : : . :. :::. *:: ::*:.*:: . .::.:* :: : : . :. . ", "identical_positions": 50, "similar_positions": 128, "identity": "7.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111201-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9V7-1", "uniprot_id": "D4A9V7_RAT", "id": "D4A9V7-1", "name": "Methionine--tRNA ligase, mitochondrial", "aln": "MLRQCALWVLTRTPAGR---------GCRRYSSCSPSASGDAREARAYFTTPIFYVNAAPHIGHLYSALLADALCRHRRLRVPGSGSTRFSTGTDEHGLKIQQAAATAGLA-PIELCDRVSAQFLQLFREAGISSTDFIRTTEARHRVAVQHFWGVLEARGLLYKGIYEGWYCASDECFLPEAKVTRQVGPSGDPCPVSLESGHPVSWTKEENYIFKLSQFREPLQRWLRNNPQAITPEPFHQVVLQWLE--EELPDLSVSRRSSHLHWGIPVPGDDSQTIYVWLDALVNYLTVVG----------------YPDA----------DFKSWWPATSHIIGKDILKFHAIYWPALLLGAGLRPPHRICVHSHWTVSGQKMSKSLGNVVDPRTCLDRYTVDGFRYFLLRQGVPNWDCDYYDEKVVKLLDSELADALGGLLNRCTAYRINPSGTYPSFCAACFPSEPGLMGPSVRVQAEDYALVNAVATLPKLVAGYYNDFQIYKALEAVSSCVRQTNGFVQRHAPWKLTWESPA-DAPWLGTVLHVALECLRVFGTLLQPVTPNLADKLLSRLGVSTTERSLG----ELYFLPRFYGHPCPF-EGRKLG-PDTGLLFPR-LDQSRTRLVKAHRT------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q499X9-1", "uniprot_id": "SYMM_MOUSE", "id": "Q499X9-1", "name": "Methionine--tRNA ligase, mitochondrial", "aln": "MLRQCARWVLTRTRFGR---------GCRRYGSCSPSASGDAGEARAYFTTPIFYVNAAPHIGHLYSALLADALCRHRRLRVPGSASTRFSTGTDEHGLKIQQAAATAGLA-PIELCDRVSAQFLQLFREADISSTDFIRTTEARHRVAVQHFWGVLEARGLLYKGIYEGWYCASDECFLPEAKVTRQVGPSGDPCPVSLESGHPVSWTKEENYIFKLSQFREPLQRWLGNNPQAITPEPFHQAVLQWLE--EELPDLSVSRRSSHLHWGIPVPGDDSQTIYVWLDALVNYLTVVG----------------YPDA----------DFKSWWPATSHIIGKDILKFHAIYWPALLLGAGLRPPHRIYVHSHWTVSGQKMSKSLGNVVDPRTCLDRYTVDGFRYFLLRQGVPNWDCDYYDEKVVKLLDSELADALGGLLNRCTAYRINPSGTYPSFCAACFPSEPGLTGPSVRVQAEDYALVTAVATLPKLVAGYYNDFQIYKALEAVSSCVRQTNGFVQRHAPWKLNWESPE-DAPWLGTVLHVALECLRVFGTLLQPVTPNLADKLLSRLGVSTTERGLG----ELYFLPRFYGHPCPF-EGRKLG-PDTGLLFPR-LDQSRTRLVKAHRT------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96GW9-1", "uniprot_id": "SYMM_HUMAN", "id": "Q96GW9-1", "name": "Methionine--tRNA ligase, mitochondrial", "aln": "MLRTSVLRLLGRTGASRLS--LLEDFGPRYYSSGSLSAGDDACDVRAYFTTPIFYVNAAPHIGHLYSALLADALCRHRRLRGPSTAATRFSTGTDEHGLKIQQAAATAGLA-PTELCDRVSEQFQQLFQEAGISCTDFIRTTEARHRVAVQHFWGVLKSRGLLYKGVYEGWYCASDECFLPEAKVTQQPGPSGDSFPVSLESGHPVSWTKEENYIFRLSQFRKPLQRWLRGNPQAITPEPFHHVVLQWLD--EELPDLSVSRRSSHLHWGIPVPGDDSQTIYVWLDALVNYLTVIG----------------YPNA----------EFKSWWPATSHIIGKDILKFHAIYWPAFLLGAGMSPPQRICVHSHWTVCGQKMSKSLGNVVDPRTCLNRYTVDGFRYFLLRQGVPNWDCDYYDEKVVKLLNSELADALGGLLNRCTAKRINPSETYPAFCTTCFPSEPGLVGPSVRAQAEDYALVSAVATLPKQVADHYDNFRIYKALEAVSSCVRQTNGFVQRHAPWKLNWESPV-DAPWLGTVLHVALECLRVFGTLLQPVTPSLADKLLSRLGVSASERSLG----ELYFLPRFYGHPCPF-EGRRLG-PETGLLFPR-LDQSRTWLVKAHRT------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q9I2-1", "uniprot_id": "A0A8M9Q9I2_DANRE", "id": "A0A8M9Q9I2-1", "name": "Methionine--tRNA ligase, mitochondrial", "aln": "MSSPCCVIASTKLIIHRLCRHVQHRRLPHAYSIAHFCTDRSQSPKAYYITTPIFYVNAAPHIGHVYSAVTADCLHRYKLLQRYNS---RLATGTDEHGLKIQQAAGSAGKD-PLNFCTEVSESFKHVFQRCGISYTDYIRTTEKRHRQAVEHFWTVLLSKGYIYKGTYEGWYSTPDESFLTETQVTDSTDSEGRRIKVSTESGHKVEWMNEDNYMFRLSDFRTQLLHWLRSNPNTIQPVKFQHLVLQWLED-DDIPDLSVSRQKSRLQWGIPVPGDPEQTIYVWLDALVNYLTVVG----------------YPQN----------HSK-WWSVVHHVVGKDILKFHAIYWPAFLLAAGLALPQKIYVHSHWTVKGKKMSKSIGNVINPLESIEKFTVDGLRYFLLRQGVPDSDCDYYDDKVMKMCNSELADALGGLLNRCAAPSLNPTQVYPRFSTSCFP----AVGPSGKAVSEDYRMIEAVSALPGIIEQHFENLYVYKALEAIGACVRLTNGFVQRHAPWRLDRNNPE-EQQWLDTILHVSLECLRIYGILLQPVVPDLADKILSRLGVTPEERSWN----SLNFLNKFQGRECAL-EGRALG-PDLGVLFSR-LERSQIKGKTTKKGTQPKSKS-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFL5-1", "uniprot_id": "SYMM_DROME", "id": "Q9VFL5-1", "name": "Methionine--tRNA ligase, mitochondrial", "aln": "-------MLIRRIKCLR-------------YLGTRYNSS-------HYVTTPIFYVNAAPHIGHLYSAVIADAHCRYQRLRYPEQ-DVRLCTGTDEHGTKIQQAASLHGVP-VAKYCDDISQRYREVFRSASIQQDDFIRTTEDRHKRAVANFWRTLHTRGHIYSAAYSGWYCVSDETFLTDSQLRLDEATG---TRYSLESGHPVEWTEETNYMFRLSQFQDDVRHWVKTEAR-VRPAKFEKILLDTLS--EPLPDVSVSRPSNRVHWAIPVPDDDSQTVYVWLDALVNYLSSVG----------------YPDE----------KFSAHWPPAQQVIGKDILKFHGIYWTAFLLAAGLEPPGQLYVHSHWTVDGQKMSKSKHNVVDPLQAAQQYTMEGLRYFLLREGVAHSDGNYSHVKAQRILNSELADTLGNLLSRASAKSLNPGQIYPSPSAEHLA-------DLLRSLDVAKRLQDSLLQLSERCESHYECNHFHLVADTTMAALHAANNFFESSKPWTLKAGAPDGNQARLETIIAMTMDALRLSGIVLQPIIPQLANRLLDKLSVPTAQRGWNYLAESFATSPNSSNSPAGLGESRQLDGQTSALLFQRILEETSAKEVKEQKPQPAKRSKSKKKERRETMS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P22438-1", "uniprot_id": "SYMM_YEAST", "id": "P22438-1", "name": "Methionine--tRNA ligase, mitochondrial", "aln": "--------MQCRSIVHR------------LYSKVS------------HVTTPIFYPNAKPHLGHLYSSLLSDVYHRWQLFKGNLS---FFTTGTDEHGLKIQCASESNGFDQPKKFVDKLYPEFVQLDKIYGINYTRFIRTTDPDHIENVMKLWELCLKNGYIYMGEHKGWYSISDETFYPESKVIKDPKNDG--KYLNTESKNEVVYQSETNYFFRLSLFNKKIVDHIRKNPDFIFPASKRDQILKELETGGTLPDLSISRPSARLKWGIPTPNDPSQKVYVWFDALCNYLSSIGGIPSILSNATEVVSRHYSDKSNVKGQLLIPYPKEVQRNTIHVIGKDIAKFHTVYWPSFLLAAGLPLPRQIVVHGHWLCNGMKMSKSLGNVVDPIDMARYYGADIVRWFLLENSKLEEDGDFQEAKLYETR-ELLVSKWGNLINRCCGSKFNIERAVMKFSDKANFQFQEIFQNEPIVSERIENLAKLLNKSQEVFDEKIAIFQYPQLLRHVWSIINDANTLVQNSKPWERELDQQD-------NIIFLAMETSRILSILCQSIIPSLSQSFLDRIDVSKEKRTIN---YARLGSDKTYGKQSNK-KGREVPLKKIPFRLQE--EQTNMRS------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * :.****** ** **:**:**:: :* * : :: : ******* *** *: * : : : .: : .*. :****: * * ::* .* :* . :.***. .** * .:::: . . ** : * : .* **:*:** *. : : :. : * .. :*. *. :**:*:** . :::*.**.*.* .*.:***:*** ***: :* *.: . . :::**** *** :**.::**.**: * :: **.** * ***** **::* : : .*:***.:. . * :: . * . . *.. *.*:.*. . :* . : : : :. :* :.: ** .:: :::: *: . : *.: *.*:: :*.::.*. :* . . . . :.* : . : . :.: ", "identical_positions": 130, "similar_positions": 155, "identity": "20.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111201-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9ULD0-1", "uniprot_id": "OGDHL_HUMAN", "id": "Q9ULD0-1", "name": "2-oxoglutarate dehydrogenase-like, mitochondrial", "aln": "MSQLRLLPSRLGVQAARLLAAHDVPVFGWRSRSSGPPATFPSSKGGGGSSYMEEMYFAWLENPQSVHKSWDSFFREASEEAFSGSAQPRPPSVVHESRSAVSSRTKTSKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSFVPSDLITTIDKLAFYDLQEADLDKEFQLPTTTFIGGSENTLSLREIIRRLENTYCQHIGLEFMFINDVEQCQWIRQKFETPGVMQFSSEEKRTLLARLVRSMRFEDFLARKWSSEKRFGLEGCEVMIPALKTIIDKSSEMGIENVILGMPHRGRLNVLANVIRKDLEQIFCQFDPKLEAADEGSGDVKYHLGMYHERINRVTNRNITLSLVANPSHLEAVDPVVQGKTKAEQFYRGDAQGKKVMSILVHGDAAFAGQGVVYETFHLSDLPSYTTNGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVIYVCSVAAEWRNTFNKDVVVDLVCYRRRGHNEMDEPMFTQPLMYKQIHRQVPVLKKYADKLIAEGTVTLQEFEEEIAKYDRICEEAYGRSKDKKILHIKHWLDSPWPGFFNVDGEPKSMTCPATGIPEDMLTHIGSVASSVPLEDFKIHTGLSRILRGRADMTKNRTVDWALAEYMAFGSLLKEGIHVRLSGQDVERGTFSHRHHVLHDQEVDRRTCVPMNHLWPDQAPYTVCNSSLSEYGVLGFELGYAMASPNALVLWEAQFGDFHNTAQCIIDQFISTGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSNDDSDAYPAFTKDFEVSQLYDCNWIVVNCSTPANYFHVLRRQILLPFRKPLIIFTPKSLLRHPEAKSSFDQMVSGTSFQRVIPEDGAAARAPEQVQRLIFCTGKVYYDLVKERSSQDLEEKVAITRLEQISPFPFDLIKQEAEKYPGAELAWCQEEHKNMGYYDYISPRFMTILRRARPIWYVGRDPAAAPATGNRNTHLVSLKKFLDTAFNLQAFEGKTF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FGK9-1", "uniprot_id": "E7FGK9_DANRE", "id": "E7FGK9-1", "name": "2-oxoglutarate dehydrogenase-like, mitochondrial", "aln": "MNQLRPLAGALRSSSQWMRGHVGTGKRVFDLRRNCSSGVTEPSLAACSSSYVVEMYYAWLEDHKNVHESWDAYFRNAEASSSVESGE-KPLSMLLQGRTMSQTPAMSEKVVEDHLAVHTLIRAYQVRGHHVARLDPLGILTADLDSFVPSDLITSIDKLASYGLEESDLDKSFQLPLTTFIGGNENTLPLREIIHRLETSYCGHTGVEFMFINNMEQCQWIRQKFETPGIMKFSAREKRTLLARLVRSTRFEDFLARKWSSEKRFGLEGCEVLIPALKMIIDKSSEAGIESVIMGMPHRGRLNVLANVVRKDLDQIFCQFDPKLEAADEGSGDVKYHLGMYHERINRETDKNITLSLMANPSHLEAVDPVVQGKTKAEQFYRGDTEGRRVMSILMHGDAAFAGQGVVYETFHLSELPSYTTYGTIHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNADDPEAVMYVCKIAAEWRTTFNKDVVIDLVCYRRFGHNEMDEPMFTQPLMYKQIRKQEHVLKKYADKLISEGVVTLQEFEEEVAKYDKICEEAYTSSKDEKILHIRHWLDSPWPDFFKPDGEPKSMSCPSTGLSEEVLKHIGEVASSVPLKDFAIHSGLSRILRGRADMITKRMADWALAEYMAFGSLLKDGIHVRLSGQDVERGTFSHRHHVLHDQEVDKRFCVPMNHLWQNQALYTVCNSSLSEYGVLGFELGFAMANPNALVCWEAQFGDFHNTAQCIIDQFISAGQAKWVRHNGIVLLLPHGMEGMGPEHSSARPERFLQMSKDDPDRYPEYTGDFEVQQLYDCNWIVVNCSTPASYFHVLRRQILLPFRKPLIIFTPKSLLRLPEARSSFDEMVTGTKFIRVIPDDGPASKNPEKVKRVIFCTGKVYYELAKERKQLKLEENVAIVRLEQISPFPFDLIKAEVEKYSNAELIWCQEEHKNMGYYDYIRPRFLTVQPKN-PIWYVGRDPAAAPATGNKFTHLAELKRFLDTAFNLEAFQDKSF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*** *.. * .: : . .. : * . .... .* .. .***: ***:****: :.**:***::**:*. .: *.: :* *:: :.*: .: : :.*:*******::******:******:******* *************:***** *.*:*:****.**** ******.****.*****:***.:** * *:******::**************:*:**:.************ ***********************:***** ******* ***.**:**************:****:********************************* *::******:**************************::*::*****:*******************:****** **:*********************************************:***.:*****.*******:******* *******************::* **********:**.*********:****:****** ***:*****:********.**: *******:**:**:.*::*.***.*******:** **:************ .:* .***************:*****************************:* ******** :** *******************:***.***** *********************:**************************************:**.* ** :* ****.****************.*************************** ***:****:**:**.* ****:**.*:: **:*:*:*********:*.***.. .***:***.************** *.***..*** *************** ***:*: : *****************: ***..**:********:**:.*:*", "identical_positions": 786, "similar_positions": 152, "identity": "77.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111207-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZWF2-1", "uniprot_id": "D3ZWF2_RAT", "id": "D3ZWF2-1", "name": "", "aln": "METAAAPGPGWAAEGERRRRRCSRRDRDREQRRRRGPGGDAPRALLAAPRGSSSSSSPPPPARPWSSASSGERPGGLRRRRPRPRPRPPRPRARKRPAGSGSRGEEEEEEEEGGADDGEAEEEPEEEEEEEDLIDGFAIASFASLEALQKDASLQPPERLEHRLKHSGKRKRGGSSGATGEPGDSSDREPGRPPGDRPRKWPNKRRRK--EAFSRHSLEAGYICDAESDLDERVSDDDLDPSFTVSTSKASGPHGTFNGN-----------CEAKLSVVPKVSGLERSQEQPPGPDPLLVPFPPKDPPPPPAPRPPVSSPTPLPATPSLPPPPQHQLQLRVSPFGLRTSPYGSSLDLSTGSSSRPPPKAPAPPVAQPPPSSSSSSSSSSSASSSSAQLTHRPPTPSLPLPLSSHSFPPHGLRPPPPPHHPSLVSPGPTLPPPPPLLQVPGHPGASAANALSEQDLIGQDLNSRYLNAQGGPEVVGAGGSARPLAFQFHQHNHQHQHTHQHTHQHFTPYPPGLLPPHGHMFEKYPGKMEGLFRHNPYMAFPPAVPGLPPGLPPAVSFGSLQGAFQPK-----NTNPELPPRLGPVLSGLPQKGTQIPDHFRPP---LRKPGKWCAMHVRVAYMILRHQEKMK---GDSHKLDFRNDLLPCLPGP-----------YGALPPGQELSHPASLFTATGAVHAAANPFTTAPGAHGPFLSPSTHIDPFGRPTSFASLAALSNGAFGGLGSPTF-----------------------------NSSAVFAQKESPGAPPA--FASPPDPWGRLHRSPLAFP---AWVRPPETARTPGSDKERPMERREPSVTKEEKDRD-LPFSRPQLRVSPATP--KARAGE------------------EGVRPAKESVRVKE--ERKEEAAAAAAAAAAAAAAAAAAAAAAAATTGP---------------QGLHLL------------------------------------------------------------------------------LERPR------------------------PPPFLGP-----SLPDR----------------------------------CAGFPEPTW------------------LAGPPRLARPP------------------------------------------------------------------RFYEAGEELTGPGAMAAARLYSLDPAHPLLYSRLAPPPPPTATPGTPH-------------------LLSKTP--PGAL-LGAPPPLVPAP-RPSSPPRAPGPARADR-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R089-1", "uniprot_id": "FBRS_MOUSE", "id": "Q8R089-1", "name": "Probable fibrosin-1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFEKYPGKMEGLFRHNPYMAFPPAVPGLPPGLPPAVSFGSLQGAFQPK-----NTNPELPPRLGPVLSGLPQKGTQIPDHFRPP---LRKPGKWCAMHVRVAYMILRHQEKMK---GDSHKLDFRNDLLPCLPGP-----------YGALPPGQELSHPASLFTATGAVHAAANPFTTAPGAHGPFLSPSTHIDPFGRPTSFASLAALSNGAFGGLGSPTF-----------------------------NSSAVFAQKESPGAPPA--FASPPDPWGRLHRSPLAFP---AWVRPPETARTPGSDKERPMERREPSVTKEEKDRD-LPFSRPQLRVSPATP--KARAGE------------------EGARPAKESVRVKE--ERKEEAAAAAAAAAAAAAAAAAAAAAAAATTGP---------------QGLHLL------------------------------------------------------------------------------LERPR------------------------PPPFLGP-----SLPER----------------------------------CAGFPEPTW------------------LAGPPRLARPP------------------------------------------------------------------RFYEAGEELTGPGAMAAARLYSLDPAHPLLYSRLAPPPPPTATPGTPH-------------------LLSKTP--PGAL-LGAPPPLVPAP-RPSSPPRAPGPARADR-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HAH7-2", "uniprot_id": "FBRS_HUMAN", "id": "Q9HAH7-2", "name": "Probable fibrosin-1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFEKYPGKMEGLFRHNPYTAFPPAVPGLPPGLPPAVSFGSLQGAFQPK-----STNPELPPRLGPVPSGLSQKGTQIPDHFRPP---LRKPGKWCAMHVRVAYMILRHQEKMK---GDSHKLDFRNDLLPCLPGP-----------YGALPPGQELSHPASLFTATGAVHAAANPFTAAPGAHGPFLSPSTHIDPFGRPTSFASLAALSNGAFGGLGSPTF-----------------------------NSGAVFAQKESPGAPPA--FASPPDPWGRLHRSPLTFP---AWVRPPEAARTPGSDKERPVERREPSITKEEKDRD-LPFSRPQLRVSPATP--KARAGE------------------EGPRPTKESVRVKE--ERKEE------AAAAAAAAAAAAAAAAAAATGP---------------QGLHLL------------------------------------------------------------------------------FERPR------------------------PPPFLGP-----SPPDR----------------------------------CAGFLEPTW------------------LAAPPRLARPP------------------------------------------------------------------RFYEAGEELTGPGAVAAARLYGLEPAHPLLYSRLAPPPPPAAAPGTPH-------------------LLSKTP--PGAL-LGAPPPLVPAP-RPSSPPRGPGPARADR-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GY24-1", "uniprot_id": "A0AC58GY24_DANRE", "id": "A0AC58GY24-1", "name": "", "aln": "-------MDGPSRSGGFRQSRRSRSQRDRERRRRRADLTEHR-----------PSSPSSASDQELCRGDSLLRAGGGECRPGFPGTRHRPPRRRKR----------------------------ESVSCEEDIIDGFAIASFISLEALEMDCSLKPPERSGIMGRGSKRKRGLDENGGPLSEPEEGPPATYTNSWDQRRKIKSKLKRKGDAKISGNHMETGYICDTESESGDKASDN-MEPAFIVFTSEAVNANSASAAAGNGCPLLPSNSSVPLLSVTPRVSGLERSQERS-MEQPYPEPISTSSSLPSLAAHSTASVSNLLPEQRNGNGGPHHRHNASSPQHKHKN----------------FLPFHLKSQSMYPMGNNNRSSTSGKPPASSSSSSSIRPPTPATSVSLGRGPGGVGTVRPSSRPSPGAVFTPSPSLPPPPPLMQVSPHPSTDQDLILTESNGASASGGPSVSNSNSGTSSRSSQAQTSIPTMAYQFHHHNHQHQHTHTHQHFLHPTAAPPP---QLFEKYPGKIDGLFRHPFFPQYPPSVPGIQPVLPSTGPFSSLHGAFQPKLVALQGAAPEMTSGLGVVPPHLQPK-ARLTDSFAPPPKVSNKPGKWCAMHVRVAWMILRHQEKVKLMHADPQKLDLRNELLPRLPGPGIGGLGGLGPLGGPLGPAHDLTRPGGLFAATGGVNPSSTPFMPPSTPHSSFLTPAAHLDPYVHSPHFSSLGALGSGAFGGLGSPTIGLGMSSVSSVCTNQKSNTVKECEWLQVDLSAASVFGHKTEPSASAVGGLGNPHDPWNRLHVPPASFPSGSSWAKGPEKR----EDRGKEVERRELTHIKDEKDRDSILYGRQPVRMSPGVPSLKHRSSTPSSHINGLGSLTGSGVQSDGQSRERERERERESDKRHHSASRPPASASSTAPDRPRSSTSSILTTSPSNVPLATSPLDLFHRQPSHTLGTESSHSSQRENNGPASSSSSSSLPVKKPDRTTTPVSKPALGLASGLLVAQVKVKEERKEEPEPVPISYTHPAVPSHNFERPSSRHPHHPSTPSSTLSLTPTPGVPLPPPTPHPPHHPLSLLDRSRAMDYGTAGLVLGAATDRFAPHPHGPPQGHSQPTPSFPWETWRDLAIHQQQQQQRRELLTLRSDPHLALRSEPHYRLQRYFDAERAVVAAAVANSPHHPPVPTSTSAASASVGRPDFGLISHQFEDERAHMLRDDRVRYFGMHPHLAAPHLSSPSHAAHLEQLHAGLLSHSHLHPAGAAAQASHHPDFYSRLGHLHSHPHVPNGILTKTPNLVGALSIGAPPRLIPSVNRSATPPRGPRLGGAGELTLFATHKDSESR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*******::***** : :**:***: * **.: .*.**:****** .: **:.. ** * . * * :::.* * ** .*************:********:* .*.:***:**:*** **** *.* *.::*::*..**:***.*:.::.** ... .*..**:*::*:**: :.. *:**.**..**********: .:.:**.:* .*.*... :..* ***.*** .* :** :*.: ** .*: : :**** : *:***** : :.* :*:**..* * *:. :* :* * :* :*:.. :*:::*. . ::::: :*.* * * * :*** *** * * :* ..* ** * . *:** . *:: .*:.* :.:: *: *. * *: *. :*: .: * :*:*** *** :**** *:*: *.::***.* . *.. ", "identical_positions": 203, "similar_positions": 155, "identity": "15.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111207-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LDS2-1", "uniprot_id": "A0ABK0LDS2_RAT", "id": "A0ABK0LDS2-1", "name": "Dual specificity protein phosphatase", "aln": "MAMGCGTTQCLYALCYDDPIKGPAAAMSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVIPRVYVGNASVAQDITQLQKLGITHVLNAAEGRSFMHVNTSASFYKDTGITYMGIKANDTQEFNLSAYFERAADFIDQALAHKNGRVLVHCREGYSRSPTLVIAYLMLRQKMDVRSALSTVRQNREIGPNDGFLAQLCQLNDRLAEEGKDPWN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D7X3-1", "uniprot_id": "DUS3_MOUSE", "id": "Q9D7X3-1", "name": "Dual specificity protein phosphatase 3", "aln": "--------------------------MSSSFELSVQDLNDLLSDGSGCYSLPSQPCNEVVPRVYVGNASVAQDITQLQKLGITHVLNAAEGRSFMHVNTSASFYEDSGITYLGIKANDTQEFNLSAYFERATDFIDQALAHKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSTVRQNREIGPNDGFLAQLCQLNDRLAKEGKVKL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P51452-1", "uniprot_id": "DUS3_HUMAN", "id": "P51452-1", "name": "Dual specificity protein phosphatase 3", "aln": "--------------------------MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXY0-1", "uniprot_id": "E7EXY0_DANRE", "id": "E7EXY0-1", "name": "Dual specificity protein phosphatase", "aln": "------------MKKHHSPAKAPLEVTVTDTEATVQQLNKLLSDGSGFYSLPAQHFNEVFPRIYIGNAFVAQNVMRLQRLGVTHILNVAEGNSFMHVNTNAEFYAGTGITYHGIQANDTEQFNISAFFEEAADFIDKALAHGKGKVYVHCREGYSRSPTIVIAYLMLRHKMDVRVATATVRHKREIGPNGGFLCQLCQLNEKLAKEGKLKTK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * :**:**.******* ****:* *** **:*:*** ***:: :**:**:**:**.***.*******.*.** .:**** **:****::**:**:**.*:****:***: :*:* ************:******:*:****: * : **::******.***.******::**:*** ", "identical_positions": 122, "similar_positions": 42, "identity": "57.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111209-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A5R8-1", "uniprot_id": "A0A8I6A5R8_RAT", "id": "A0A8I6A5R8-1", "name": "non-specific serine/threonine protein kinase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDEPSLLRRRG--------------LQKELSLPR-----------------------RGRGLSPSSQSPCLLSPGSPCSPCSPSLGLQQPWSCRSGNRKSLVVG---TPSPTLSRPLSPLSVPTAGNSPLDSPRNFS-AAAAINFPFAR-------RADGRRWSLASLPSSGYGTNTPSSTVSSSSSSRERLHQLPF----------------------------------------------QPTADELRFLS-------------------------------KHFRSSESVVDEDGGRSPRLRPRSRSLSPGRTSGTFDNEIVMMNHVYRERFPKATAQMEGRLQDFLAAFAPGDRLALADG--VLGFIHHQIVELARDCLAKSGEALVTSRYFLEMQDKLERLLQDAHERSDSAEVGFIVQLVRKLLIIISRPARLLECLEFDPEEFYHLLEAAEGQAREDQGVKTDLPRYIIRQLGLAKDPLEEIQPLN---------------DLDEGQP----PAPGSPESRGLG------------------------------------------------------------------------------GPSRRQPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFVDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVILYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEG-DEALPPDAQDLITRLLRQSPMDRLGTG-GTHEVKQHPFFLALDWAGLLRHKAEFVPQLEAEDDTSYFDTRSERYRHLGS-EGDETNDEESSTEIPQFSSCSHRFSKVYSSSEFLAVQPNPTFA-ERSFS--EDREEGWEQSGEGDGGRRLST-DLRLRS-WTP-ASSCQPSSC-------------------QSDRGPSPSLLS-TISLD-MPKFAFSS----------------------EDEGAGSGPADTRKPVFILGEPDPPPPTTPVTPKPCNLSADTAVLSHARLRSNSTGARHSTPRPLDAGRGRR--------------------------LGSSRDPGPEKPRASP-----GGSGGRVP--------KSASVSALSLIITADDGSGGPLMSPLSP----RSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIHSSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEEGSPAQEAGLRAGDLITHINGESVLGLVHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMAR-----RSKRSRRRETQDRRKSLFKRISKP--------------SSVLHTSR-------SFSSGLQHSLSSSESLPGSPTHSLSPSPTTPCRS------------------------------PAPDVPTDT-ASPPSVSPSSSSPASPATG-HTRPSSLHGLAAKLGPPRH-KSG------------------------RRKSTSSIPPSPLACP----PVPTPPPRSPSPLP----------------------------------------GHIPIPARSPRLRRGQSADKLGLGTSERLDGDGGRR------------GRGAE---------------------------------TELVVMRRLHLSERRDSFKKQEAVQEVS-------FDE----EPGPTGA---------------------------VPKIAVQGAEATPGSPGPARED---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U214-1", "uniprot_id": "MAST3_MOUSE", "id": "Q3U214-1", "name": "Microtubule-associated serine/threonine-protein kinase 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKSR----------------REKLLIPA-----------------------LTLDLSPSSQSPCLLSPGSPCSPCSPSLGLQ-PWSCRSGNRKSLVVG---TPSPTLSRPLSPLSVPTAGNSPLDSPRNFS-AAAAISFPFAR-------RADGRRWSLASLPSSGYGTNTPSSTVSSSSSSRERLHQLPF----------------------------------------------QPTADELRFLS-------------------------------KHFRSSESVVDEDGGRSPRLRPRSRSLSPGRTSGTFDNEIVMMNHVYRERFPKATAQMEGRLQDFLAAFAPGDRLALADG--VLGFIHHQIVELARDCLAKSGEALVTSRYFLEMQDKLERLLQDAHERSDSAEVGFIVQLVRKLLIIISRPARLLECLEFDPEEFYHLLEAAEGQAREDQGVKTDLPRYIIRQLGLAKDPLEEIQPLN---------------DLDESQP----PAPGSPESRGLG------------------------------------------------------------------------------GPSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENPFVVGMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARMYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFVDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVILYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEG-DEALPLDAQDLITRLLRQSPMDRLGTG-GTHEVKQHPFFLALDWAGLLRHKAEFVPQLEAEDDTSYFDTRSERYRHLGS-EDDETNDEESSTEIPQFSSCSHRFSKVYSSSEFLAVQPTPTFA-ERSFS--EDREDGWGQS-LGDRGRRLSA-DLRLRS-WTP-ASSCQPSSC-------------------QTDRGPSPSLLS-TISLDVMPKFAFSS----------------------EDEGASSGPADPQKPVFILGEPDPPPPTTPVTPKPCNLSADTAVLSHARLRSNSTGARHSTPRPLDAGRGRR--------------------------LGGSRDPGPEKPRASP-----GGSGGRVP--------KSASVSALSLIITADDGSGGPLMSPLSP----RSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIHSSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEEGSPAQEAGLRAGDLITHINGESVLGLVHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMAR-----RSKRSRRRETQDRRKSLFKRISKP--------------SSVLHTSR-------SFSSGLQHSLSSSESLPGSPTHSLSPSPTTPCRS------------------------------PAPDAPTDT-ASPPNVSPSSSSPASPATG-HTRPSSLHGLAAKLGPPRH-KSG------------------------RRKSTSSIPPSPLACP----PVPTPPPRSPSPLP----------------------------------------GHIPIPARSPRLRRGQSADKLGLGTSERLDGDGGRR------------ARGAE---------------------------------AELVVMRRLHLSERRDSFKKQEAVQEVS-------FDE----EPGPPRG---------------------------VPKIAVQGAEATPGTPGHARKD---------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60307-1", "uniprot_id": "MAST3_HUMAN", "id": "O60307-1", "name": "Microtubule-associated serine/threonine-protein kinase 3", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDESSLLRRRG--------------LQKELSLPR-----------------------RGR-------------------------------GCRSGNRKSLVVG---TPSPTLSRPLSPLSVPTAGSSPLDSPRNFS-AASALNFPFAR-------RADGRRWSLASLPSSGYGTNTPSSTLSSSSSSRERLHQLPF----------------------------------------------QPTPDELHFLS-------------------------------KHFRSSENVLDEEGGRSPRLRPRSRSLSPGRATGTFDNEIVMMNHVYRERFPKATAQMEGRLQEFLTAYAPGARLALADG--VLGFIHHQIVELARDCLAKSGENLVTSRYFLEMQEKLERLLQDAHERSDSEEVSFIVQLVRKLLIIISRPARLLECLEFDPEEFYHLLEAAEGHAREGQGIKTDLPQYIIGQLGLAKDPLEEMVPLS---------------HLEEEQP----PAPESPESRALV------------------------------------------------------------------------------GQSRRKPCESDFETIKLISNGAYGAVYLVRHRDTRQRFAIKKINKQNLILRNQIQQVFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMARLYFAETVLALEYLHNYGIVHRDLKPDNLLITSLGHIKLTDFGLSKIGLMSMATNLYEGHIEKDAREFIDKQVCGTPEYIAPEVIFRQGYGKPVDWWAMGVVLYEFLVGCVPFFGDTPEELFGQVVSDEIMWPEG-DEALPADAQDLITRLLRQSPLDRLGTG-GTHEVKQHPFFLALDWAGLLRHKAEFVPQLEAEDDTSYFDTRSERYRHLGS-EDDETNDEESSTEIPQFSSCSHRFSKVYSSSEFLAVQPTPTFA-ERSFS--EDREEGWERS-EVDYGRRLSA-DIRLRS-WTSSGSSCQSSSS-------------------QPERGPSPSLLN-TISLDTMPKFAFSS----------------------EDEGVGPGPAGPKRPVFILGEPDPPPAATPVMPKPSSLSADTAALSHARLRSNSIGARHSTPRPLDAGRGRR--------------------------LGGPRDPAPEKSRASSSGGSGGGSGGRVP--------KSASVSALSLIITADDGSGGPLMSPLSP----RSLSSNPSSRDSSPSRDPSPVCGSLRPPIVIHSSGKKYGFSLRAIRVYMGDSDVYTVHHVVWSVEDGSPAQEAGLRAGDLITHINGESVLGLVHMDVVELLLKSGNKISLRTTALENTSIKVGPARKNVAKGRMAR-----RSKRSRRRETQDRRKSLFKKISKQ--------------TSVLHTSR-------SFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRS------------------------------PAPDVPADTTASPPSASPSSSSPASPAAAGHTRPSSLHGLAAKLGPPRP-KTG------------------------RRKSTSSIPPSPLACP----PISAPPPRSPSPLP----------------------------------------GHPPAPARSPRLRRGQSADKLGTG--ERLDGEAGRR------------TRGPE---------------------------------AELVVMRRLHLSERRDSFKKQEAVQEVS-------FDEPQEEATGLPTS---------------------------VPQIAVEGEEAVPVALGPTGRD---------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AXH0-1", "uniprot_id": "A0A8M3AXH0_DANRE", "id": "A0A8M3AXH0-1", "name": "non-specific serine/threonine protein kinase", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKRR-----------------DKLKIPS-----------------------LTLDLSPS-QSPIILSPCSPGSPCSPLQSLH-PWSCRSSNRKSLGVG---TPSP--TRPLSPLSAHTAASSPLDSPRNVSTAICSLNFPFARSHLARADRAEGRRWSLASLPSSGYGTNPPSSTVSSSSSSQERLHQLPY----------------------------------------------QPTQDELHFLF-------------------------------KHFRSSESMTDEDGRPSTFIRPRSRSLSPGRTGGSFDNEIIMMNHVYKERFPKATAQMEERLLDIIRHFSPDSTLPLGDG--VLGFIQHQLVELARDCLDKSQKGLITSLYFIELQDKLEKMLHEALDRSESEEVSIITQLIKKILIIISRPARLLECLEFDPEEFYHLLEAAEGHAKVGQGIKTDIPRYIISQLGLNWDPLDEVVQLE---------------EQFDSGPTLTVDSQESAEQNKVS------------------------------------------------------------------------------TPLRRKPLESDFETLKLISNGAYGAVHLVRHKETRQRFAMKKINRQNLILRNQIQQVFVERDILTFAENPFVVSMFCSFETRRHLCMVMEYVEGGDCATLLKNMGPLPVDMTRMYFAETVLALEYLHSYGIVHRDLKPDNLLITSMGHIKLTDFGLSKIGLMNMTTNLYEGHIEKDTREFIDKQVCGTPEYIAPEVILRQGYGKPVDWWAMGIILYEFLVGCVPFFGDTPEELFGQVVSDEIIWPDG-DDALPVDAQDMITRLLNQSPLERLGTG-GAPEVKQHMFFSGLDWNGLLRQKAEFIPQLEGEDDTSYFDTRSERYHHLASDEDEETNDEESSLEIRRFSSWSNRFSKVYSSTEHLATPSNLSFSSDRSHS--EEIEDRADTHYHGEIQRQASTGDKRLSAQRASLRPRTSSSSS-------------------QPERAVSPLVVSSTHSLEAMPRFALST----------------------DDEAEVVVSN----------------------------------LRRIRLRSNSTGTKHSSPR--EQGGPPC--------------------------FGNQLET-PDKQRLSP--------GRKVP--------KSASVSTLSLIITPDDGSGSLQGRSISP----RSFSSNPSSRDSSPNRDLSLSISRLRPPIIIHSSGKKFGFTLQTIRVYMGNSDIYTIHHMVSGVEESSPAHEAGLRAGDLITHVNGESVQGLVHTEMMELLLKSGNQVTLQTIALEDTSIKIGPARKSRCKGKMAR-----RCK-SRWKDNKDRRRNMLKKLSKQ--------------STVMHSSR-------SFSSGLHHSVSSSESLPGSPTHSLSSGPTTPCRS------------------------------PVPDHTTDT-GLPQNASPCSSSPSSPAVQ--MRPSSLHGLGSKLGNQRYTKVG------------------------RRKSTSSIPPSPLACTSS--PQALSPQRSPSPLPSISKTLHSFHG---------------KTLSPPTIIRHVVRPRSAEPPRSPLLKRVQSAEKLSGALFADKKPHAARRHTLEVPHCELDVSGDAEGEVACGSVYTTDHGRLGGYLCAQRLRDWPSERMEQIVVMRKLNLSERRDSFKKQEAVQEVS-------FDEPDAPQTSAQTGTSTGTRPKHIMGESQSEEECVARRNPLVPQIAVQGSESEEADDWRLCSDEDEDEAEEN-----------VLLTRNQGEPRIHTANISSVATCEATGVITVTAMPENHPNPEKSKLINR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUQ9-1", "uniprot_id": "Q9VUQ9_DROME", "id": "Q9VUQ9-1", "name": "non-specific serine/threonine protein kinase", "aln": "MSRQEGAASRPADGATGPVASSSSSTSSNHSVSAVLGSKISTSTPQKNDEHQEQEFINQSVASEIEAMSISDSASAESSSGATATATATMSGSPVPKRHLSTANLSRIRPQSSYSARVLIFDDSDQEAAAAAAALAAASSSCNSSVKSCSGLELLPTSPAKLSIGNDSTNGSSMMRNLNLTKSSSGGLSGSSSSLHSRGYTALLRKISYQQHTNSLRAVSGETSNLLRMRHSSLGKSAPCLTGNYFRHELTAPLPVQPPGFGASPLGGHNISRSGSCAGIGLAKHHHHHHLHGVVMRGSAGGGAGSGGGSSSGVAHHRLSLVTNSAAVAAAGGSRTHSPYSASPVDSPRLNSPMPFAFAPIKRIASCRG------VVADGRRWSVASLPSSGYGTTPGSSNLSSQCSSQEGLNQLAHNIPPGVQEADAAAVAAGACCAEHLKQHCPKHCALLLAVSQKQLTPQPPKPTQLQPQKSMTAACVNCCAELSVTCGGQQAGGGAANGGSSANSSGSSAMQVGGRMSPYFRPRSRSLSSPSRSPIVDNEIAVMNTLYKERFPKATQQMEERLKLFINENKSAACNSFRDSQPIVRFVHHQVLEMARDCLHKSEAKLITSQYFYELSENLERLLVETKEKS-PEAAAELNGVIKKLLLIISRPARLLECLEFDPQEFYELLEAAEGHAKAMPVIKADIPQYIIHKLGLNRDPIAELQQELRETQQMCSEQVTVDADPLHPGGSLLLNSPLTSAAKQLSSLALDAIAMDSGSGTATPQQPPQTPVATCDTAPSFALAISQMNEEKGGSSSAVGGGSSSKVAGAEGITGGSAATATGSGAQQPSPQENDFDIVKLISNGAYGAVYLVKHKTTRQRFAMKKINKNNLILRNQVEQVFAERDILSFADNPFVVSMYCSFETKKHLCLVMEYVEGGDCGTLLKNIGPLPADMARFYFAETVLAVEYLHSYGIVHRDLKPDNLLITALGHIKLTDFGLSKMGLMSLATNLYEGYIDSETRQFSDKQVYGTPEYIAPEVILRQGYGKPVDWWSMGIILYEFLIGCVPFFGETTEELFAHTVNDDIEWPDSEDWPVQAEAKDIISQLLQQNPRDRLGTQSGALEMKEHEYFLGMDWNSLLRQKAEFVPQLSHDDDTSYFDTRMDRYNHDLG--GEDTDDTDDTPVFGSFNSYTPQYRKQHYSWSRHATPTSTDGAKPTGPPPLSSLPSRAQETPAATVGATSTGALPKLKSGMGSGSGSGSGSGSGSASHDGVVNKFLNTPQLRKLDLSSSCLKVPSTPDADYLPELLHNVTIGNDAELRMLKHYLQQPNPGATQRMQQRHSMPPNTTTIISTPATPPPTQTQATMAATPPTATVGSFSRSTPESSQTDSDDFSPQINRKRKGVCARDILPRFSISIEDETISAGSSSTENMNLPREQSPLALQHQPKSMDGSTSGSSVKHHRSRSIVKSASALGLSLMTSLDNSQLAAQLCGIQSPGGGGNGSSTASSRDTSPCRELSPLVTNLKPPIIIRRGPRGFGFTVHTIRVYYGDTDFYTMHHLVMAVDEGSPAFEAGLRPADLITHVNGEAVQGLFHTQVLQLLLSGGEHVTLRATPLEHTSIQSGGRKRDLMQSKLAKKGVNRQKKQTKREHDKKRKTSLFRRISSKRANAEMQQYSAGTSSPTTPSARNLSPLDSSYHSSCCQSAANSSSQSTSPSSSSPNTPTGSSGSNHGGNAGSVAVAPSALSVQLPSAPPPTQLVLLPHVGAVVGSNPTSVGNVPVSPTGVVPQLYQRPSTLHGLKHKLHAATAVIAGGGNANNPAGGLKTLHTTNNNSLPNRRKSVGHIPLSPLARTPSPSPLPSSPTRSPSPLAFPLVGHQPGASNTTQSYSPGSTLPTLQTAVNANTKKAGFARTKSAEPSSPLLRRALSPDRLHPRSAETKISPLCCSPPIKQPTHQRVVTTTWRSTPGGSASGAGGAVLGAPSVQPLQLVPAASEESQRQTAMATVVSTTAAGTDPSATAVVTLANCEPLPRIAEEKDSPTSTQDSSSVSEGFMPAIEEFAEGESSSSPTQTLEKPTKVKATEQPEMEPAGKSKKVDQGKTTTPGTPKTKPHNSGCKTSMTTTKPASPSVTISTAPRKDTSAVTGGGSSGSGGSAATSAAKQRK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * .:* * . : :* ** .. ..:. :*. ** *. .. .. *:** .: * . *:*****:**********.. **.:**..**:* *:**.. *. :*: . *... : * *. :********. .**** :** :*:******* *** ** :: . .: *. :: *::**::*:***** ** *:** ** *:.::**::* :: ::* . .. : :::*:*:****************:***.*******:*: :*:*:*:*** :*** **: *: . . : :. . : : .* *.**: :***********:**:*: ******:****::*******::***.*****:**:*****.*:*****::***:**********.*****:****.**:*:********:****.****************::************:***.::******:*:.::*:* **** ***********:***********:**::*****:*******:*.****.:.*.*:* **:. * .: :*:*:*::**.*.* :**** *: *:*:* :* .:** .***:****:***. :********* :**.* . .::*:* :.: : *.* : :: * : * . *. .. : . . .. . : :* : . . *.. : : . * : * . : :*.: . :. . : : .*.. .: . :*: :. : * : .. * * ****. ***: : *:.. . :.. . **..****:** *: * *:***:*: . : :**::::**** *::*.**:**:* .*::.*** *****..*****:***:* **.* ::::***..*::::*:: .**.***: * ::. :.::*: : * :: .. :.*: .:::::*. :.. ::* *: *. :* :.*.* . **: * . ** .. * *. : . . * ... . **:. . ***:**** ** * ****.. ** **** . * . .* ******. . . ** *:* *.::* . . ..* : : .: . ** :: : * .. . *:. * . ", "identical_positions": 504, "similar_positions": 374, "identity": "23.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111212-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M7G0-1", "uniprot_id": "F1M7G0_RAT", "id": "F1M7G0-1", "name": "non-specific serine/threonine protein kinase", "aln": "---------------------------------MQVKKSWIERVFYKRECNKFIPSSKDPHRCTPG------------------CQICQNLVRCYCGRLIQEHQG-----------------------------------------LDRAWSLSATEGNGNEQWSVEKHTVKSPTDTFGTINFQ-DGEHIYHSKYIRTSWDTKSDHLLHLMLKEWNMELPKLVISVHGGLQNFKMPSKLKETFSQGLVKAAETTGAWIITEGINSGVSKHVGDALKAHSSMSLRKIWTVGIPPWGVIENQRELVGKDVVCMYQTLSNPLSKLTTLNCMHSHFILCDDGTVGKYGNEEKLRRNLEKHLSMQKIHTCSRQGVPVVGLVVEGGPNVILWVWETVRNKE--PVVVCEGTGRAADLLAFTYKHSEDG--GILRPQVKEEILCLIQNMFNFSLRQSKHLFQILMECMVHKDSITIFDADSE---EHQDLDLAILKALLKGTSLSISEQLNLAMAWDRMDIAKKHILIYGQHWKPGALEQAMRDALVMDRVDFVKLLIENGVNLHRFLTISRLEDLYNTKQGPTNKFLRHLVQDVKQHTLLSSYRITLIDIGLVIEYLIGGAYRSSYTRKSFRVLYNDLYRKHKGMTSFAQGLSQHPLHQRHSLGNRKESSESTLHSQFFRTAQPYKSKDKPEDSHKPKKKSKERHSLSEDPGSAGFIYPYNDLLVWAVLMKRQKMAMFFWQHGEEATVKAVIASILYRAMAREAKESNMVDDTSEELKKYSEQFGQLALDVLEKAFKQNEPMAMKLLTYELKNWSNSTCLKLAVSGGLRPFVSHSCTQMLLTDMWMGRLKMRKNSWLKIIISILLPPMILTLEFKSKAEMSHVPQSQD-FQFTWNYSDQGLSNTKE---AKDYDLERGPDEKLDEALHLDLRN-------------------VPQSLPWTRRVYEFYSAPFVKFWFYTMAYLAFLMLFTYTVLVEMQPQPSVQEWLVIIYIFTNAIEKVREICISEPSKFTQKVKMWLSEYWNLMETVAIGLFAVGFGLRWGHPPLHTAGRLIYCIDIIFWFSRLLDFFAVNQHAGPYVTMIAKMAANMFYIVIIMAIVLLSFGVARKAILSPKEPPSWRLARDIVFEPYWMMYGEVYASEIDVCS----NETSCPPGSFLTPFLQAVYLFVQYIIMVNLLIACFNNIYLDIKSISNKLWKYNRYRYIMTYHQKPWLPPPFILISHLCLLLRGLCCRPAPQDQEEGDMGLKLYLTKDDLKKLHDFEEQCVEKYFHEKTEGLNCSCEEQIRATSERVSEMFFQLKEMNEKVSFIKDSLLSLDSQVGHLQDLSALTVDTLKVLS---AVDTLQEDEILLANRKHSTCRKRPHSWTNVICAKVLTDMESCGKQKFQYYSMPPSLLRSLARSQLPPGVQRGALVEVTHNTREASHVREDQKEREVEQRTIASGVSHVRQAHSKYGQFLLVPPSEKQVSLSLENPPHLFRASGETGTDDVALQHRHPSDVTIHLPGQTPAVSHQALGAEHKDQHEAVIQMSGKPDKAEQDSLKFSGTPAPMAVTSLPSRAISMQDEGGYVNWAFSESDEAGVFSFKKKWKTCLASTCDSGSKPGGDCSLQAAGRSGLDNSR-LAQSCEW-PAGPWTQARRSFWINPLCRDKPLLKSHSFRFHKEEKLRKTWKNNSHSKASETGS-TWLKAKLLTKNRSLSKKRRKAQGLQVPVITVNACY-QSDQLTSESGETNTT-EDYSKNWLSVSNFSQIGLEPYIYQKMKMKEIERHTTQASYHLRQMQEDPDKNPSWNSRSASVSRSFLTRSPNEVDKISASLKSPPE-PHRHYSAIERNNLMRLSQTIPFTPIQLFTGEEVTIYKLEETSPLTLDKSMSSWSQHGRAAIIQVLS-QEEMDGGLR----KAMRVISTWSEDDVLKPGQVFIVKSFLPEVVQTWYKIFQESTVLHLCLREIQQQRAAQKLIYTFNQVKPQTIPYTPRFLEVSLVYCHSANQWLTIEKYMTGEFRKYNNNNGDEIAPTNTLEELMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKPEDKQSRG-MVFGPANLGEDAIRSFIAKHRCNSCCGKLRLPDLKRNDYSHARAHCNLELAKTTEPAEEHPERDRNRSPLEDHTRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIR4-1", "uniprot_id": "TRPM6_MOUSE", "id": "Q8CIR4-1", "name": "Transient receptor potential cation channel subfamily M member 6", "aln": "---------------------------------MQVKKSWIEGVFYKRECNKFIPSSKDPHRCTPG------------------CQICHNLVRCYCGRLIEEHHG-----------------------------------------LDRAWNLSVTEGHGDEQWSVEKHTVKSPTDTFGTINFQ-DGEHIHHSKYIRTSWDTKSDHLLHLMLKEWNMELPKLVISVHGGLQNFKISSKLKETFSQGLVKAAETTGAWIITEGINSGVSKHVGDALKAHSSKSLRKIWTVGIPPWGVIENQRELVGKDVVCMYQTLGNPLSKLTTLNCMHSHFILCDDGTVGMYGNEEKLRRNLEKHLSMQKIHTCSRQGVPVVGLVMEGGPNVILWVWETVKNKE--PVVVCEGTGRAADLLAFTYKHLEDG--GILRPQVKEELFCLIQNMFNFSLRQSKHLFQILMECMVHKDSITIFDADSE---EHQDLDLAILTALLKGTSLSISEQLNLAMAWDRMDIAKKHILTYGQHWKPGALEQAMLDALVMDRVDFVKLLIENGVNLHRFLTIPRLEELYNTKQGPTNKFLRHLVQDVKQHTLLSSYRITLIDIGLVIEYLIGGAYRSSYTRKSFRILYNNLYRKHKSVSSFAQGLSQHSLHQRHSLRNRKESSESTLHSQFFRTAQPYKSKEKPEDSQKSKKKSKERQSLSEEPEAAGFIYPYNDLLVWAVLMKRQNMAMFFWQHGEEATVKAVIASILYRAMAREAKESNMVDDTSEELKNYSEQFGQLALDVLEKAFKQNEPMAMKLLTYELKNWSNSTCLKLAVSGGLRPFVSHSCTQMLLTDMWMGRLKMRKNSWLKIIISILLPPMILTLEFKSKAEMSHVPQSQD-FQFTWNYSDQGLSNTKESACVKDYDLERGPDEKPDEPLHLDLRN-------------------VPQSLPWTRRVYEFYSAPFVKFWFYTMAYLAFLMLFTYTVLVEMQPQPSVHEWLVIIYIFTNAIEKVREICISEPSKFKQKVKMWLSEYWNLMETVAIGLFAVGFGLRWGHPPLQTAGRLIYCIDIIFWFSRLMDFFAVNQHAGPYVTMIAKMAANMFYIVIIMAIVLLSFGVARKAILSPKEPPSWRLARDIVFEPYWMMYGEVYASDIDVCS----NETSCPPGSFLTPFLQAVYLFVQYIIMVNLLIACFNNIYLDIKSISNKLWKYNRYRYIMTYHQKPWLPPPFILLNHLCLLLRGLCCRPAPQDQEEGDGGLKLYLTKDDLKKLHDFEEQCVEKYFHEKTEGLNCSFEEQIRMTSERVSEMFFQLKEMNEKVSFIKDSLLSLDSQVGHLQDLSAITVDTLKVLS---AVDTLQEDEILLANRKHSTCRKRPHSWTNVICAKVLSDMESCGKKKLQYYSMPPSLLRSLARSQLPPSVQRGALVEVTHSKREASHVREEQEEREMEQRTTASGISHVRQAHSKYGQFLLVPSSGKQVPLSLETPPHLFRSSEEAGIDGLVLEHIHQSDLTTHLPQQTPAASHQALVAEHKDQHEAVTQMSDKPAKAEQDLLAFSGTPAPMTVTSLPSRAISMQDEGGYVNWAFSENDETGVFSFKKKWKTCLASTCNSDSNPGGDYFLHTGGRSGLDNSRRLAQSCEC-PAGPWTQARRSFWINPLCRDKALIKSHSFRFHKEEKLRKTWKNNSHSKSLETRS-TWLKAKLLTKTRSLSKKKRKTQGLQVPVITVNACY-QSDQLNAEPGETNTT-EEFSKKWLSVSNFSQIGLEPYIYQKMKMKEIKRHTTQASDHLRQPQENRDKTPTWNSGSTSLSRSFLTRSPNEVHKISTSLKSPQE-PHHHYSAIERNNLMRLSQTIPFTPIQLFTGEEVTIYKLEESSPLTLDKSMSSWSQHGRAAMIQVLS-QEEMDGGLR----KAMRVISTWSEDDVLKPGQVFIVKSFLPEVVQTWYKIFQESTVLHLCLREIQQQRAAQKLIYTFNQVKPQTIPYTPRFLEVSLVYCHSANQWLTIEKYMTGEFRKYNNNNGDEIAPTNTLEELMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKPEDKQSRG-MVFGPANLGEDAIRSFIAKHRCNSCCGKLRLPDLKRNDYSLSRTHCNLGFGQTIEPTEELPERDKNRSSLEDHTRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BX84-1", "uniprot_id": "TRPM6_HUMAN", "id": "Q9BX84-1", "name": "Transient receptor potential cation channel subfamily M member 6", "aln": "------------------------MKEQPVLERLQSQKSWIKGVFDKRECSTIIPSSKNPHRCTPV------------------CQVCQNLIRCYCGRLIGDHAG-----------------------------------------IDYSWTISAAKGKESEQWSVEKHTTKSPTDTFGTINFQ-DGEHTHHAKYIRTSYDTKLDHLLHLMLKEWKMELPKLVISVHGGIQNFTMPSKFKEIFSQGLVKAAETTGAWIITEGINTGVSKHVGDALKSHSSHSLRKIWTVGIPPWGVIENQRDLIGKDVVCLYQTLDNPLSKLTTLNSMHSHFILSDDGTVGKYGNEMKLRRNLEKYLSLQKIHCRSRQGVPVVGLVVEGGPNVILSVWETVKDKD--PVVVCEGTGRAADLLAFTHKHLADE--GMLRPQVKEEIICMIQNTFNFSLKQSKHLFQILMECMVHRDCITIFDADSE---EQQDLDLAILTALLKGTNLSASEQLNLAMAWDRVDIAKKHILIYEQHWKPDALEQAMSDALVMDRVDFVKLLIEYGVNLHRFLTIPRLEELYNTKQGPTNTLLHHLVQDVKQHTLLSGYRITLIDIGLVVEYLIGRAYRSNYTRKHFRALYNNLYRKYK--------------HQRHSSGNRNESAESTLHSQFIRTAQPYKFKEKSIVLHKSRKKSKE-QNVSDDPESTGFLYPYNDLLVWAVLMKRQKMAMFFWQHGEEATVKAVIACILYRAMAHEAKESHMVDDASEELKNYSKQFGQLALDLLEKAFKQNERMAMTLLTYELRNWSNSTCLKLAVSGGLRPFVSHTCTQMLLTDMWMGRLKMRKNSWLKIIISIILPPTILTLEFKSKAEMSHVPQSQD-FQFMWYYSDQNASSSKESASVKEYDLERGHDEKLDENQHFGLES-------------------GHQHLPWTRKVYEFYSAPIVKFWFYTMAYLAFLMLFTYTVLVEMQPQPSVQEWLVSIYIFTNAIEVVREICISEPGKFTQKVKVWISEYWNLTETVAIGLFSAGFVLRWGDPPFHTAGRLIYCIDIIFWFSRLLDFFAVNQHAGPYVTMIAKMTANMFYIVIIMAIVLLSFGVARKAILSPKEPPSWSLARDIVFEPYWMIYGEVYAGEIDVCS----SQPSCPPGSFLTPFLQAVYLFVQYIIMVNLLIAFFNNVYLDMESISNNLWKYNRYRYIMTYHEKPWLPPPLILLSHVGLLLRRLCCHRAPHDQEEGDVGLKLYLSKEDLKKLHDFEEQCVEKYFHEKMEDVNCSCEERIRVTSERVTEMYFQLKEMNEKVSFIKDSLLSLDSQVGHLQDLSALTVDTLKVLS---AVDTLQEDEALLAKRKHSTCKKLPHSWSNVICAEVLGSMEIAGEKKYQYYSMPSSLLRSLAGGRHPPRVQRGALLEITNSKREATNVRNDQERQETQSSIVVSGVSPNRQAHSKYGQFLLVPSNLKRVPFSAETVLPLSRPS---VPDVLATEQDIQTEVLVHLTGQTPVVSDWASVDEPKEKHEPIAHLLDGQDKAEQVLPTLSCTPEPMTMSSPLSQAKIMQTGGGYVNWAFSEGDETGVFSIKKKWQTCLPSTCDSDSSRSEQHQKQAQDSSLSDNSTRSAQSSECSEVGPWLQPNTSFWINPLRRYRPFARSHSFRFHKEEKLMKICKIKNLSGSSEIGQGAWVKAKMLTKDRRLSKKKKNTQGLQVPIITVNACS-QSDQLNPEPGENSISEEEYSKNWFTVSKFSHTGVEPYIHQKMKTKEIGQCAIQISDYLKQSQEDLSKNSLWNSRSTNLNRNSLLKSSIGVDKISASLKSPQE-PHHHYSAIERNNLMRLSQTIPFTPVQLFAGEEITVYRLEESSPLNLDKSMSSWSQRGRAAMIQVLS-REEMDGGLR----KAMRVVSTWSEDDILKPGQVFIVKSFLPEVVRTWHKIFQESTVLHLCLREIQQQRAAQKLIYTFNQVKPQTIPYTPRFLEVFLIYCHSANQWLTIEKYMTGEFRKYNNNNGDEITPTNTLEELMLAFSHWTYEYTRGELLVLDLQGVGENLTDPSVIKPEVKQSRG-MVFGPANLGEDAIRNFIAKHHCNSCCRKLKLPDLKRNDYSPERINSTFGLEIKIESAEEPPARETGRNSPEDDMQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q2T2-1", "uniprot_id": "A0A8M9Q2T2_DANRE", "id": "A0A8M9Q2T2-1", "name": "non-specific serine/threonine protein kinase", "aln": "----------------------------------MSRCTWIQATFCKRECVRFLPASRDHHRCYPV------------------CQVCQSLVRCCCGRLIAEHVGP---------------------------------------YSGLLGHDPGSGSAEEEEWSVLQHTSLSPTDAFGSLDFQGSSKRACRAKYVRLSCDSPPELLVQLMLREWHMEIPKLVITVHGGTDNFLLSPRVCQAFSTGLVTAAESTGAWILTDGINTGVSKYVGDAVKMYGSHDHRKRNVVGITPWGIIENNSDLIGRDGLRHYQALGNPLSKRASLNGMHSHFLLVDDGTIGKSGCQIELRKRLERHIHYQKIHPRLPQHVPLVCVVVEGGPSVLSVVLEYVCRTSPVPVLVFEGTGRAADMLALIHKQTAVD--RKLDSDIKEDVLQRIQDSFGVERSESTELLDILMECMEHRELISIFDSESE---DLQEADVAILSTSLRGTRASPEEQLSLTLAWDRADIAKDHILVYGQQWQVGSLEQIMLDALIMDRVNFVKLLIENGMTMSHFLTISRLEQLYNIQTGSSHHFLRHVIADAKQTRLPAVYRISLIDIGMVIEYLIGGAYRSTYTRKRFRTMYSRLHNPAKETSS----------PFSKAKKVAPAPEATPPRSHFRRTAQPYRHQEGGVAPQDQK----------SDP-IPDFVCTFNDLFVWAVLKHRQEMALLLWQHGEQAMARAVVACKLYRTLAMEAKESNMGDTMAEELKKNSLEFGQLAVDVLDQAFRENERMAMKLLTWEMKDWSNFTCLQMAVSSGLRPFVAHNCTQMLLTDLWMGRLNLSKNSWFKIIGSILMPVAIQLLEFKSQAEMSHVPQLQEALQFGWDTVPSEQEGAEK---AVPGDEERGSS----------------------------------CLYPWTRKVYDFYTAPVVKFWFHTMAFLGFLMMFAYTCLVRLNETPNIQECLVMTYILAMAVEKAREVLVLEPRKFTKKLKVWFSEYWNINDFLGILLFLVGVSLRW-HQETRLASHIVYSLDFVFWSVRLLDLFAVNQHAGPYLTMITKMMSNMFYIVIIMALVLVSFGTSRKSILSPNEDPSWTLLRDVVFQPYWMIFGEVYAGEIDACA----NPETCVPGAFLTIFLQAVYLFIQYIIMVNLLIAFFNNVYNEMSTISRKLWKYNRYRYIMTYQEKPWLPPPLIFLSHITLCLSSMWQKHR-KASKRGRTGLKLILAPDDLKRLYEFEEKCVAGYFRDQKESQQGSQINRIRSAADKAEEMAGILVEVAEKVNIIQDNLRTLDTNLGQLQDLSALAVDTLNLLS---ATDNQQQEVARLGQSHPHACRHEQVSHSCCLRIGGSVAPSQALPSPKHYRSMPPSLLRGLG-----PGRQRLSMELPPGTSVGPFEVR----------SKCLLGSPEEEDCHFRWP--LLRGDSREGVSMDCHLSLPHLCTG-------------WRDRGMYGSGEASRASSPNMPLMRDFQLHPSHEESMEEEDDDEDDLHSLSRASS--HTFLLTDTQRDMDGAMGIRNPAFYKVDEGGHF------------------LRPHDVLSRKFEAYGLEQSRSLSASVES-------MAMPDTSTSEQGRRIYLTPPHHSHDHKG------------------------LSKLFRRQRSFGKKSVRSRAGTPEEVKVDETRGRLHEFDSRRKMKRKVKGLFDRRFRTSVSLTQLNVDQVDITKLAPSWLS-----------------SGQPLLSSWTRSISQRPSVSSMTDVR--SSTFKLTED-LGQHYSAMERNNLMRLAHTIPFTPVSLLGGVEVCIYTLEES-VGDPSSSISTWLQNGRTAVLQPLAHQEVLDGGLR----RATKVVCTWAEGDVLKLGSVYVVKAFRPEVVRIWQKVFPISTSLHLCLREIQQQRAAQKLMQRFNQVKPSSVPHSPRFLDVSLLHWRSDGQWLTVENNMSGHFRKYNNNTGEEILPSSGLEETILAFSHWTYEYTNKELLVLDLQGVGADLTDPSLIRVDDKSSPGEMAFGPANLGDDAIQSFVLKHTCNSCCKKLGLSDLR----------SCGSLKKSVPAFDETSCTA------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8DYE2-1", "uniprot_id": "TRPCG_DROME", "id": "A8DYE2-1", "name": "Transient receptor potential cation channel trpm", "aln": "MVVTDSPLAPHKYVRRISKDFSTVRRYSNTPAVVVGSFRASTSAFIAAESAAHLPTCSSPTTRTPVSTPRGIRRRQRMRKRSSVSSTLSKVLILNVRDLLKAHAGSEPLKEHQPRSWIETNFQKRECIKFIPCPKDDTKCCCGQAQITHQTIPGIESGSPGDLWLPTKHTRPQPTDAYGTIEFQ-GGAHPTKAQYVRLSFDTRPELLVQLFTKEWNLELPKLLITVQGGKANFDLQAKLKKEIRKGLLKAAKTTGAWIFTGGTNTGVTKQVGDALLLEGQQRTGRVVSIGIAPWGIVERNHELLGHNREVPCHSISSPRSKLAVLNNRHAYFLLVDNGTQAKYGAELILRRKLEKFISNLKLHPFTHSSTPVVCLVIEGGTNTIRAVLEYVTDSPPVPVVVCDGSGRAADLLAFVHKYASDGEEQPVLESMRDYLIGTIQKTFEVGLDQSEKLYQELLQCTRNKNLITVFRIQEKPEGEAQELDQTILTALFKSQHLSPPEQLSLALTWNRVDIARSEIFVYGQEWPNGALDEAMMQALEHDRIDFVKLLLENGVSMKKFLTIPRLEELYNTKHGPANTLG-YILRDVRPH-IPKGYIYTLHDIGLVINKLMGGAYRSYYTRRKFRPIYAKVMNSYAN-------------ACRKSSTYQYQRYAGANSLSLVTGLLPFTS------------------------EMALFEFPFNELLIWAVLTKRQQMALLMWTHGEEALAKSLVSCKLYKAMAHEAAEDDLDTEIYEELRSYAKEFESKGNKLLDFSYRQDAEKAQRLLTCELHSWSNQSCLSLAVAANHRALLAHPCSQVILADLWMGGLRTRKNTNFKVILGLAMPFYIRQLDFKSKEELQQMPQTEEEHLENQNLDNDDSDRSQPDAEALLADTYSVRDTKVHENGKVSLTDSDTAQFREFFNLSEYNEVKQHQPLRLKKKFYEFYTAPITKFWADSIAYMFFLIMFSFTVLVKMEQMPRWQEWYSIAYITTLGFEKVREIISSEPVAITHKFSVWAWNMWNPCDGAAIILFVIGLAFRFRENTMDIG-RVIYCVDSIYWYLRILNILGVNKYLGPLVTMMGKMVKNMIYFVVLLAVVLMSFGVSRQAILYPNKQPTWSLIKEVTFQPYFMLYGEVFAGDIDPPCGEDPSQPGCVTGHWVTPITMSMYLLIANILLINLLIAVFNNIFNEVNSVSHQVWMFQRFTVVMEYQQKPVLPPPFIALCHFYSLLK-YCVRKAKGLEVQRDNGLKLFLEKDDLERLYDFEEECVEGFFHEQEIILNQSTDERVKNTTERVETMSQKIEDINQKENIQTATVQNIEFRLRKMEESSEQILSHLAVIHRFMSTHTAGADDLRGSTINIPGEMQRMRTISISDTEGGSGPGGNGGGGGGGGAIVPLGLGAGLN-------LNSLQVTTRRRFNRSLTEVRPDAYIFDEGTHFEVVPLPEEPDEVVKSREALNEQVVRKASMQSEADSDIYIPVS--------------QRPSTCETVKRTPYVTVRQDTGASTESKDTLTPMGNNDDDQ-----TLVGGDNSDDATPDINFEAARHRALRQRTVSLCRRNSETYSLTGADINRSHISLNQLASLSRRQMSLTQSEPDSDKDAPIAQGSAHPGKSVLHAKPSRNILLKLHSEYTSITDELESVCHMIASPTVS-----------------LPSNKASLDRPKTEMSRAEAAALLEKKHLKECEENDYMILEGLIESRGSIDASAQGFEIGVSIDYSHRYPLRRETAVELSPSKPSVDG--------DLMGGGEGGGAGGGDSSDTSGAGSCGAMVGISSGFQLKNERPWQRNSSMEQQTYPSPLVPTRATSDFLNPPYEGRLFKKSSESLQKNSSTETDYSAHPYRFIKQSSNETNTSLTGSYNVDTPSLTAEPSLDAGDSHSATGISISVGAVGGTATARYQPIRTASVGAADGRRLREESSSSLDLSSSGPVTMQAAPAPP-VRPMLLKKQFSVDQGKPSQTAAEAVPQTPEAAQAGQAKLISTLKPQPFASKLGMNVLKESSSSTDESVGSSAKSSNPALSIP--------------QISTHLVQDEIAKLSSN--------------------------IKSSTESEKDPPFNETMC---------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* *. :*:. . * .. .:: *: * * . : * :** .***::*:::** .. : :::*:* * *: : *::*: :**::*:***:*:*:** ** : .:. : : **:.**::*****:* * *:**:* ****: .. : :**.***::*.: :*:*:: :::..* ** : ** *::*:* *:** . * : **:.**:.: *:* . .*:* :*:***...: * * * . **:* :*:*****:**: :* : .::: :: **. * . :* .* : *::* ::: *::* :.: : *: * :**.: ::. * ***.*:::*:* ***:..*: * *.* .:*:: * :** **::*****:* *:.: :****.***:*** : *.:: : ::: *.: : * :* ***:*:: *:* **** ***: ** :* : . :: . : *: . * .:*:*::**** :**:**:::* ***:* .:::::. **:::* ** *..: ***:. : :* . . .:*: ::::: * *** *::.*** :**.:**:.. *.:::* *:*::*:*:*** *. **: :*:* .: :* * *:***: *:.::** :: . . :: . * . .::.*:**:**..*** ::*:: **::*::* **.:: * :* ** : ..* .**: ** :.:*..:* : ** : .* ** *. :*: . . :::*.:* ::* *:::::.**:: ** :**: ** **:*:*:::*:**:***.:*::** *:: *:* * :::.*:**:*::***:*.:** . . * .* ::* : ::**:: *:::***** ***:: ::.::*.::* ::*: :* *::** ****:* : *. * : . . **** * :**::*::***:** :*::: : * :::: ::::. * : :: :* .: .: .:: .: :::: * :. * :: :... : . : : : : :* .* .* : : . .** . : : * : . . : : : : . . : . . . :: . :. : .:: * . . . . . : * :: * : . :. . : . : : .: . . .: . . * : *: :: : :: *::*::. . *. * * :: .. ..: : : . : * : * : . : .* . : : . .. : : :: *.:::: ::. : . *. .: * .* . : * * .* . :. . :. : . : . *: :* . .. . . : * . . ::*:: ::. . ::. : * .* : . . .: . ", "identical_positions": 385, "similar_positions": 578, "identity": "17.77%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111212-11", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35763-1", "uniprot_id": "PERF_RAT", "id": "P35763-1", "name": "Perforin-1", "aln": "MAAYLFLLG-LFLLLPRPVPAPCYTATRSECKQNHKFVPGVWAAGEGVDVTTLRRSSSFPVNTGKFLRPDRTCTLCKNALMNDGIQRLPVAIAHWRPHGSHCQRNVATTKVSSTEGVAREAAANINNDWRAGLDVNPKPEANVHVSVAGSHSKIANFAAEKAHQDQYNFNTDTVECRMYSFRLAQKPPLHPDFRKALKNLPHNFNSSTEHAYRRLISSYGTHFITAVDLGGRVSVLTALRTCQLTLDGLTADEVGDCLSVEAQVSIGAQASVSSEYKACEEKKKQHKIATSFHQTYRERHVEVLGGPLDSSNDLLFGNQATPEHFSTWIASLPTRPDVVDYSLEPLHILLEDSDPKREALRQAISHYVMSRARWRDCNRPCRAGQHKSSRDSCQCVCQDSNVTNQDCCPRQRGLAKLMVRNFQAKGLWGDYITSTDAYLKVFFGGQEIRTGVVWNNNHPSWSDKMDFGNVLLSTGGPLRVQVWDADNGWDDDLLGTCDKSPKSGFHEVNCPLNHGSIKFIYQANCLPDLTGETCLEYAP---QGLLGDPRGNRSGAVW----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P10820-1", "uniprot_id": "PERF_MOUSE", "id": "P10820-1", "name": "Perforin-1", "aln": "MATCLFLLG-LFLLLPRPVPAPCYTATRSECKQKHKFVPGVWMAGEGMDVTTLRRSGSFPVNTQRFLRPDRTCTLCKNSLMRDATQRLPVAITHWRPHSSHCQRNVAAAKVHSTEGVAREAAANINNDWRVGLDVNPRPEANMRASVAGSHSKVANFAAEKTYQDQYNFNSDTVECRMYSFRLVQKPPLHLDFKKALRALPRNFNSSTEHAYHRLISSYGTHFITAVDLGGRISVLTALRTCQLTLNGLTADEVGDCLNVEAQVSIGAQASVSSEYKACEEKKKQHKMATSFHQTYRERHVEVLGGPLDSTHDLLFGNQATPEQFSTWTASLPSNPGLVDYSLEPLHTLLEEQNPKREALRQAISHYIMSRARWQNCSRPCRSGQHKSSHDSCQCECQDSKVTNQDCCPRQRGLAHLVVSNFRAEHLWGDYTTATDAYLKVFFGGQEFRTGVVWNNNNPRWTDKMDFENVLLSTGGPLRVQVWDADYGWDDDLLGSCDRSPHSGFHEVTCELNHGRVKFSYHAKCLPHLTGGTCLEYAP---QGLLGDPPGNRSGAVW----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P14222-1", "uniprot_id": "PERF_HUMAN", "id": "P14222-1", "name": "Perforin-1", "aln": "MAARLLLLGILLLLLPLPVPAPCHTAARSECKRSHKFVPGAWLAGEGVDVTSLRRSGSFPVDTQRFLRPDGTCTLCENALQEGTLQRLPLALTNWRAQGSGCQRHVTRAKVSSTEAVARDAARSIRNDWKVGLDVTPKPTSNVHVSVAGSHSQAANFAAQKTHQDQYSFSTDTVECRFYSFHVVHTPPLHPDFKRALGDLPHHFNASTQPAYLRLISNYGTHFIRAVELGGRISALTALRTCELALEGLTDNEVEDCLTVEAQVNIGIHGSISAEAKACEEKKKKHKMTASFHQTYRERHSEVVGGHHTSINDLLFGIQAGPEQYSAWVNSLPGSPGLVDYTLEPLHVLLDSQDPRREALRRALSQYLTDRARWRDCSRPCPPGRQKSPRDPCQCVCHGSAVTTQDCCPRQRGLAQLEVTFIQAWGLWGDWFTATDAYVKLFFGGQELRTSTVWDNNNPIWSVRLDFGDVLLATGGPLRLQVWDQDSGRDDDLLGTCDQAPKSGSHEVRCNLNHGHLKFRYHARCLPHLGGGTCLDYVP---QMLLGEPPGNRSGAVW----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I3IS28-1", "uniprot_id": "I3IS28_DANRE", "id": "I3IS28-1", "name": "", "aln": "MRHVPVYLLVFWAMLLIAISGEVEIGTLKECENAH-FVPGYNLAGEGFDVVTLERKGTYVINTEKWDLGNGTCNMRTNQYMNGIKQKLPAAVDFWRTLP-KCSMKVSGQIFESSEAVVEESSSAISGDWKADLSVKLSG-----ATVGGTHSREAKFAMQKSKRDKYSFTKHQVECNFYRYHVVQKPPLHAEFLQAIKLLPASYD---KFAYRSLISTYGTHYTTSVMLGGHMKAITAIKTCEASIGGLSDTAIKDCLDVEASG-IYKALTVEAEARLCRELKQKLGTNLKMSSKFSERQTEIIGGKING-EDLLFSGSSHKNALKGWLESLKSVPDVVQYTLKPLHFLLSDKHPARKGLKKAVEEYIIENALRKVCSEPCKLGKKSSARDPCVCVCESSRIMKTNCCPTEKGLATLKVYNLRANGLYGDTWTQTDGYVEVRHQGQNKRTQIIDDNDNPRWSESFNFGHINIKIGSTLTFEVYDDDDGWNCDHLGTCSVKVSSGVVNDGCALNHGTLFFSYEVKCAPSLQGPQCDEHKPSPMAASLADIFSSRNGVLVKDMQRLELAFNNSGMTHFKGDNGKLMML", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . * : :* .:.. .: .**:. * **** ****.**.:*.*..:: ::* :: : **.: * .. *:** *: **. *. :*: . *:*.*..::: * .**:..*.*. .:*.*:**: *:** :*: :*:*.*... ***.:* :::.:.**** :* :*: ** :: : ** ***.****: :* ***::..:**::**: :: **: : *** ***. * ::.:* : *.* *:: .: ..: **: *::** . .****. .: : . * ** *.:*:*:*:*** **....* *:.*::*:..*: ..* : *..** *::.*.:*.* * *..* : . :*** ::*** * * ::* *:** * **.*::: . **: ** : :*::* *: ::* .: : *..* .:*:* * * : * **:*. ** : * **** : * *...* * * * * :: * *.: ..*.*.: ", "identical_positions": 180, "similar_positions": 192, "identity": "30.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111213-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A2H6-1", "uniprot_id": "D4A2H6_RAT", "id": "D4A2H6-1", "name": "RNA binding protein fox-1 homolog 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQPYPPAQYPPPP-QNGIPAEYAPPPPHPTQDYSGQTP-----------VPPEHG--------------------------------MTLYTPAQTHPEQPGT-------------EASTQPIAGTQTVPQADEAAQTD-SQ--QLHPSDPT-----------------------------------------------------------------------------------------------------EKQQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFETSSDADRAREKLNGTIVEGRKIEVNNATARVMTNKKPGNP---YANG------------WKLNPVVGAVYG-------------------------PEFYAVTSFPYP--------TTGTAVAYRGAHLRGRGRAVYNTFR---------------------------------------------------AAPPPPPIPTYGAALEQTLVKMPVPWAGLAPCPLPPQQTPEPAYPTSPAFPPLSCPFASRVVYQDGFYGAEIYGGYAAYRYAQPAAAAAAAA---------------------YSDSYGRVYAAADP--------------------------------YHHTIG-----------------------------PTATYS---------------------------------------------IGTMASLCRGGYSRFTPY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BIF2-1", "uniprot_id": "RFOX3_MOUSE", "id": "Q8BIF2-1", "name": "RNA binding protein fox-1 homolog 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQPYPPAQYPPPP-QNGIPAEYAPPPPHPTQDYSGQTP-----------VPPEHG--------------------------------MTLYTPAQTHPEQPGT-------------EASTQPIAGTQTVPQADEAAQTD-NQ--QLHPSDPT-----------------------------------------------------------------------------------------------------EKQQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFETSSDADRAREKLNGTIVEGRKIEVNNATARVMTNKKPGNP---YANG------------WKLNPVVGTVYG-------------------------PEFYAVTSFPYP--------TTGTAVAYRGAHLRGRGRAVYNTFR---------------------------------------------------AAPPPPPIPTYGAALEQTLVKMPVPWAGLAPCPLPPQQTPEPAYPTSPAFPPLSCPFASRVVYQDGFYGAEIYGGYAAYRYAQP-AAATAAA---------------------YSDSYGRVYAAADP--------------------------------YHHTIG-----------------------------PTATYS---------------------------------------------IGTMASLCRGGYSRFTPY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NFN3-1", "uniprot_id": "RFOX3_HUMAN", "id": "A6NFN3-1", "name": "RNA binding protein fox-1 homolog 3", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAQPYPPAQYPPPP-QNGIPAEYAPPPPHPTQDYSGQTP-----------VPTEHG--------------------------------MTLYTPAQTHPEQPGS-------------EASTQPIAGTQTVPQTDEAAQTD-SQ--PLHPSDPT-----------------------------------------------------------------------------------------------------EKQQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFETSSDADRAREKLNGTIVEGRKIEVNNATARVMTNKKTGNP---YTNG------------WKLNPVVGAVYG-------------------------PEFYAVTGFPYP--------TTGTAVAYRGAHLRGRGRAVYNTFR---------------------------------------------------AAPPPPPIPTYGA-----------------------------------------------VVYQDGFYGAEIYGGYAAYRYAQP--AAAAAA---------------------YSDSYGRVYAAADP--------------------------------YHHTIG-----------------------------PAATYS---------------------------------------------IGTM--------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QJ91-1", "uniprot_id": "A0A8M9QJ91_DANRE", "id": "A0A8M9QJ91-1", "name": "", "aln": "----------MVPQTRFIGQSDLPRSDCPLLPTESD-------------TSVVAVRPQQAQPQLYMETPSWAE---------------------------------------------------------------------TKPGNGLCKTGSIALFGNVVYSGLLNDHF-WHFGVPLVTRLGNQEAPAPP-------EAMAQPYAPAQYPPPPPQNGLPGEYT----HPGQDYTGPSP-----------VPEHAAA-------------------------------LTIYTPTQTHSEPPGT-------------DSSTPSLTGTSSLTQADDVVQTDGSQQLQLQPSDSS-----------------------------------------------------------------------------------------------------EKQQPKRLHVSNIPFRFRDPDLRQMFGQFGKILDVEIIFNERGSKGFGFVTFETSADADRAREKLNGTIVEGRKIEVNNATARVMTNKKVANP---YTNG------------WKLNPVVGAVYG-------------------------PEFYAVTGFPYP--------TTGATVAYRGAHLRGRGRAVYNTFR---------------------------------------------------AAPPPPPIPAYGA-----------------------------------------------VVYQDGFYGAEIYGGYAAYRYAQP-AAAAAAA---------------------YSDSYGRVYATADP--------------------------------YHHTIG-----------------------------PAATYS---------------------------------------------VGTMASLYRGGYSRFTPY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9NFQ7-1", "uniprot_id": "M9NFQ7_DROME", "id": "M9NFQ7-1", "name": "", "aln": "MSASAVEVTGNVPPVEFHMREHMVQAGVAPFPGAPAGYAAAPNPGAAVVAAAAAAQQQQQQQQQQQQQQQQAQQQQQQQVAGGPPSAADSLSMAVAAAAAKQSADPVTQMKSGSEAAGSGNSNNNNTAGAGTGAPGAAGGLTTEYSSGGCGGGGASTANSVVVATSVSDVVNASLYMQQKTNLSTQTQTQYEYEYEYNGTSLAEPRVPGPIPHPL-TNGHAVDQVQQPPVQQQHLQSSLPPQNVLSISTVLIANEAAESQQSSAMQNAGGGGNTGGGGGGGGGGTPSSPLSNSPSSATASQAGGCGLTLNGSATEGSMSGDTSPVASGEPLLQTPPAHQQQQQQQQPLLCSSPTSMQSSGTSVTGSSIASGTLAATSSSGVGLLPTTGLDSIANGGAPTGCAVVPASTSQVIAHLNAAAAAASGIVSPSANVATSLSSALVPAQSVAAVAAASLDAKSQPKRLHVSNIPFRFRDPDLRAMFGQFGTILDVEIIFNERGSKGFGFVTFANSNDAERARERLHGTVVEGRKIEVNNATARVQTKKVTAVPNVVLTKDGAIPAPALVCVQWPEAAVAAAMRGVAIQRGHVGVVGATPYHHPHHPHHHPALLAASAAAAQQQQQRQLAAAAVATAAVAQQQQQQQQAVVQQQQQQVAAAAQQQHQQQQQQQQQAVQQQQAVQQQQQHQQQQQQQQQQQHAAVAAAAAAASHPHMHAAHAHAHAHALGPQLAQLQAVAVPTAASNAAALQQSLAAAIQNPSGNPNAAAAAAAYAARLSAATGATQSPQTAAAAAAAASMAASANAANNAAALHGFAPVYYDPFLAAAASADPNLRFQAAKPVTEVPAAQPAAILNRRTVTTLNSNPHTINRIPVPQNVLATAPLLKTPLSQAQQQAYATAATTYTAVAARAAYGAAAAAAAQPALAGYATVAGYAREYADPYLGHGIGPVPGYGATMYRGGFNRFTPY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:* *. * * ** . : . *. . * :. . . :: ..: * .: * ...* .::. ..: *: . * : .* * *..: *.******************** ******.********************* .* **:****:*:**:*************** *:* . * ::. * .*..:: * * : *.:. . ::..:.* . : : : :** : : **.... :.* .. . *.*.: .. .* : .*. **:*** * *.: . *:*** ***. .::**: * ", "identical_positions": 125, "similar_positions": 99, "identity": "12.98%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111214-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R8U7-1", "uniprot_id": "M0R8U7_RAT", "id": "M0R8U7-1", "name": "", "aln": "---KETDSNNFGELQASEAMATLAKLLSRSDFLESQYYFRNRAVDSVRKFENDAAVAIQSWFRGCQVRAYIRHLNRVVTIIQKWWRSYLGRKYYQLIVEAAYYTMKMNLYNEMAVRIQRRWRGFRIRKYCFNYYYLKEYLRAVSETNDAIREALEEFAEMKEREERKILLELEEKQKDYQARKTHYLLSTKQISGVYNSPFREHPDPWEVRLQKAKPLEHRKGSAMKSKTAHSLSSWLACTSARSFPRSASLPPIDRKRCQGPFRDINEVLEQRYKPLEPTLRVSEPIDHLHVAREAFKQEERMRNVQDKMFLPFSSYHKKETYIPMIHTLSTYDSPSYGQKYFRCQDPKKWISDKDFQTVLPSFELFSKY---GKLYSKAGQIV-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D552-1", "uniprot_id": "SPT17_MOUSE", "id": "Q9D552-1", "name": "Spermatogenesis-associated protein 17", "aln": "---METNSNNFGELQELKDMATLAKLLARAPFLESQYYFRNRAVDSFRKFENDAAVMIQSWFRGCQVRAYMRHLNRVVTIIQKWWRSYLGRKFYQLVVEAAYYTMKMNLYNEMAVRIQRRWRGFRIRKYCFNYYYLKEYLRAVSETNDAIREALEEFAEMKEREERKVLLEREEKQKDYQARKMHYLLSTKQISGIYNSPFREHPDPWELRLQKAKPLGHQKYTAEKGKTSQSPSNWLACTSVHSFPQSESLPPISRKRCQGPFRDINEVLEQRYKPLEPTLRVAEPINHLRLAREAFKQEERMRNVQDKMFLPFSSYHKKEKYIPMIHSSSAYNSDSYGQKHFRSQDSKKWISDKDFQTVLPSFQLFSKY---GKLYSKAGEIV-------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96L03-1", "uniprot_id": "SPT17_HUMAN", "id": "Q96L03-1", "name": "Spermatogenesis-associated protein 17", "aln": "-------------------MATLARLQARSSTVGNQYYFRNSVVDPFRKKENDAAVKIQSWFRGCQVRAYIRHLNRIVTIIQKWWRSFLGRKQYQLTVQVAYYTMMMNLYNAMAVRIQRRWRGYRVRKYLFNYYYLKEYLKVVSETNDAIRKALEEFAEMKEREEKKANLEREEKKRDYQARKMHYLLSTKQIPGIYNSPFRKEPDPWELQLQKAKPLTHRR-PKVKQKDSTSLTDWLACTSARSFPRSEILPPINRKQCQGPFRDITEVLEQRYRPLEPTLRVAEPIDELKLAREELRREEWLQNVNDNMFLPFSSYHKNEKYIPSMHLSSKYGPISY-KEQFRSENPKKWICDKDFQTVLPSFELFSKY---GKLYSKAGQIV-------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HNY8-1", "uniprot_id": "A0AC58HNY8_DANRE", "id": "A0AC58HNY8-1", "name": "", "aln": "------------------MMARLVKLYRQVDLIKEQHFIRNRIAEENRQKENEAAVRIQSWFRGCQVRAYIRHLHKNAILIQKTWRGFTARALFRQRVKTAYFIMKMNFYNKMAVKIQQRWRGFYVRKYVHNYYARKRYLEGLTRKNEHIRRDLEKFAEFQRRERKRIALEKEEQEKKIQAQRLHFLLSTKQCPGVFNSPFRAEPDEMELRLRTVKPLLVRS--APKERKTPNITPDLSS----VMPNRERLPPIHKK-TQGPFRPALEVQQQRYRPLEPSLRVATSITALEEAREELKLHEWRTRVIDQTFLPFSNPSRNKRYEGLMHTSTPFEQVAYGTKHFR-DEHKELLQGKKQALPSASSAIARKYLLRNEINKRALLLTPLMYAWLILDVATPFRSAF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A9F2IDH0-1", "uniprot_id": "A0A9F2IDH0_DROME", "id": "A0A9F2IDH0-1", "name": "Spermatogenesis-associated protein 17", "aln": "MPFFGSPGSTMEEDEDPSYESYFVEEDMESIIRPLAAKLTWTTVHLIDYKMFIAARRIQSFWRGYRVRKLLHLRWQSAIAIQRWWRGFRTRHILYEKVERRLQGIIHEHFHRAAIRIQALFRGWWVRKFIHDVRNLHR--MQCTAAEDLINCIIHEMHHIKKTDSIPGVISLRN---SVCRSKVEKLLTTMIFRFHNGRVLSMVANRMSQKEEYRRHFRDARFVTHIPYSGPNFDGLCYVREDDHIVLKEVPTDLRYSEIVTEYEESQLHEHLRETHLRFDLRKLQRQIDHINYQELHLKRKFCADVIDRMRKWTIWDSISANHKQNIYESRKNTQVFFRRAEHLMSDFYVSKAEDSYHVLSLSSST-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :.. . : .. ** ***::** :** :: : . **: **.: * *: : : :: *::** :**: :**: .: :. : :: *. :.:: .::. : :. .: . : . **:* . : .: . : . : : . : . : . :. . * *. ** :* .: * *. . : :: : . .: .. * ", "identical_positions": 34, "similar_positions": 86, "identity": "8.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111215-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FYB0-1", "uniprot_id": "ARSJ_HUMAN", "id": "Q5FYB0-1", "name": "Arylsulfatase J", "aln": "MAPRGCAGHPPPPSPQACVCPGKMLAMGALAGFWILCLLTYGYLSWGQALEEEEEGALLAQAGEKLEPSTTSTSQPHLIFILADDQGFRDVGYHGSEIKTPTLDKLAAEGVKLENYYVQPICTPSRSQFITGKYQIHTGLQHSIIRPTQPNCLPLDNATLPQKLKEVGYSTHMVGKWHLGFYRKECMPTRRGFDTFFGSLLGSGDYYTHYKCDSPGMCGYDLYENDNAAWDYDNGIYSTQMYTQRVQQILASHNPTKPIFLYIAYQAVHSPLQAPGRYFEHYRSIININRRRYAAMLSCLDEAINNVTLALKTYGFYNNSIIIYSSDNGGQPTAGGSNWPLRGSKGTYWEGGIRAVGFVHSPLLKNKGTVCKELVHITDWYPTLISLAEGQIDEDIQLDGYDIWETISEGLRSPRVDILHNIDPIYTKAKNGSWAAGYGIWNTAIQSAIRVQHWKLLTGNPGYSDWVPPQSFSN-LGPNRWHNERITLSTGKSVWLFNITADPYERVDLSNRYPGIVKKLLRRLSQFNKTAVPVRYPPKDPRSNPRLNGGVWGPWYKEETKKKKPSKNQAEKKQKKSKKKKKKQQKAVSGSTCHSGVTCG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1REG3-1", "uniprot_id": "F1REG3_DANRE", "id": "F1REG3-1", "name": "", "aln": "MGSLSTHGQMEKST----------FLLTLLTTFSCIVSSTYG--TWKSGFQSN-----LVNNMDKPN------SQPHIIFIMVDDQGFRDVGYHGSEIKTPTLDRLAAAGVKLENYYVQPLCSPSRSQLMTGRYQIHTGLQHSIIRPTQPNCLPLENITLPQKLKNAGYSTHMVGKWHLGFYKRACMPTQRGFDTFFGSLLGSGDYYSHYKCDSPGLCGYDLHEGEEAAWEQDRGVYSTIMYTQKAVNILASHNPKRPIFLYLAFQAVHSPLQVPARYLERYKSIPNLHRRKYAAMVSCLDEAVRNLTLALKQYGYYDNMVMVYSSDNGGQPMAGGSNWPLRGSKGSYWEGGIRAVGFVHSPLLVKKGTKSKALIHITDWYPTLVMLGEGTLDENQNLDGYDVWEAISEGRPSPRLDILHNIDPIYTKAKNGSWKAGYGIWNTAVQAALRVGDWKLLTGVPGYSDWIPPQTFSTLLLANRWHNERVSWDRGKSVWLFNITADPYERVDLSRQYPHVVKKMLFKLLRYSKNAVPCRYPPKDYRSNPQYNGGVWGPWYTDDDQDEDDNLLSYDLEQMKSWKKAKRRGKFKRKI---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. . *: .: : : *: * : *** :* ..::.: *.: :* : ****:***:.*********************:*** ***********:*:*****::**:**********************:* *******:.***************:: ****:*****************:********:*****:*.::***: *.*:*** ****:. :*******.:*****:*:********.*.**:*:*:** *::**:****:******:.*:***** **:*:* :::********* *************:***************** :*** .* *:*********: *.** :**: :*****:**:**** ***:****************** *********:*:*:** .****** ******:***:**. * .*******:: . ********************.:** :***:* :* ::.*.*** ****** ****: *********.:: :.:. . . : :* ** ** *:: * ", "identical_positions": 388, "similar_positions": 115, "identity": "64.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111215-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M5N3-1", "uniprot_id": "F1M5N3_RAT", "id": "F1M5N3-1", "name": "", "aln": "-------MMNEDAAQKSD--------------SGEKFNGSSQRRKRPKKCVCSG--LRLSKARTLS--SHNFSA--SKPDFFFSQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLEKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVT--EEVTTTTTTITEKHKLNVPETMTEVLDVSDE------------------EGDDTVTGDGGEYLRPEDLKE-LGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSHASYLRDSAMIDDTVVIPSHQVSALAKEAERNSYRLSWGTENLDNVALSSSPIHSG------------FLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLG---------------------------------PVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCEYTEDELNEILNG--MDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVSQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNG----FGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVAFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFSEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRG-LVHQAICNLNITLPIYAKESESDQEQEEEVILQQQHY-DETESTETSVLKSHLVNEVPVLASPDLLSEVSEMKQDLIKMTAILTTDVSD----------------------------KAGSIKVKELAKAGEEEPGEPFEIVERVKEDLEKVNAILRSGTYMRDEGSVRSSQSER-ELEEEWVIVSDEEIEEAKQHAPVEIAEHPCVEVRVDRETKTKVE--KDSTG-------------------------------------------------------------------------------------LVNYLTDDLNSYTGTHEKKPQTAPEKSGETSQASAIVKSSESNKGKTSPAEEKQSAQKQVKPSLVIKKPVRRKLKEKQKQKEESPQGSEEKTELKKGSSEESVD--------------------------------EDRGLAP-EPLPTAKATSPLIEETPIG-----SIKDKVKALQKRVEDE-----QKGRSKLPVRVKGKEDVPKKTTPRTHPVVSP-SSKS------SPSSK-------------------------------MERHSSLTSSAKTERHSPVSPSSKNEKHSPVSPSAKAER-------HSPVFSG-KPEKHSP----------GSPSTKNERHSPVSS-------IKTERHTPVSPSGKTDKRPPVPSSGRTEKHPPVSPG-------------KTEKRSPG--APSIRTPEKQAPGSATGKHEKHLPVSP-GKTEK----------------------------------------------------QPPISPTSKTERIEETMS--------------VRELMKAFQSGQDPSKHKTG----------------------------------------LFEHKSAKQKQSQDKSKSRVEKE---KGHSVTQ-----RETQRIENQTAKR----------------------------------------------------------------GQRFQVTGAMESRRFRSTTITVGLRTEDPVRERFERTPVIKTPEAVPPVAAAVAAAAAEESHRGAETLQEKTVDEQED-----------------------------------------------------------------------------------------------MDLQISPDRKTSTDFSDVIKQELEDNDKYQQFR--------------------------------------------------------------------LTENTEKAQIHLDQVITSPFNTTFP--LDYMKDEFLPALSLQSGALGGSSESLKQEVIAGSPCGSLMEGTPQISSEES-------------YKHEGLAETPETSPESLSFSPKKSKEQIG------EAKETIKVETPTDIHSEKELPITNDIADSSEKQGAGVPGDSE----HVLKEVTQVPPKDVCSK-QEDCPGSHSVSLANETCQALTEEGSCRDSQLPLVSSACKTQAVSETQESLATSEVTKAFPPSDATVKTVEGTEPKPQGVIRSPQGLELPLHNRDSEVLSPMADESLAVSHKDS-----------------LEASPVLEDNSSHKTPDSLEPSPLKESPCRDSLESS------------------------------PVEPKMKAGILPSHFPLP----AAIAKTDLVAEVASMRSRLLRDPDGSAEDDSLEQTSLMESSGKSP---LSPDTPSSEEVSYEVTPKPSDS---------------------------------------------STPKPAVIHECAEEDDSENGEKKRFT-PEEEMFKMVTKIKTFDELEQEAKQKRDYKREPRQDESSSSSDPDADCSAEVDEQK----------------------QMGSTEGESDVPVLVTSESRK----------ASSSS-------------ESEPELTQLSKGADSGLLTEPVIRVQPPSPLPSSIDSNS----SPEEA------QFQPIVPKQYTFKMNEEVKEDPGNPEEDKDCKSHLAEDSQTHSADGADGS--HADLNRETP-QLEACDGHGCKAVSPSNSATPVSLG-----------VQSPECHDVDKPLAIDNDSLALQDTHG-------SDLEEREFD-----------------------------PSRVESTQASLPSE-HSSLSSSSHCAVPEENESAKEISSPSSPVKVEV--------------------------------TVTDPVLESMSEDCPTQEASTTTHTERFAMDGPVSDIAETDENS----HPQITSPYENVASSSFFSGEPSNFQTDTCHPTVVHSPEVYSVIIRSSPEDVIMTSSSSRTDSGEASNCEGHDLD-----------------------------------------TECEQKSALWPMQSDEP------------------PLSVAPTTPNAPVV------------------TGEQVSKVIITKTDVDADSWSEIRE--------DDAAFEARVKE---------------------------EEQKIFGLMVDRQSQGTTPDTTPARTPTEEGTPTSEQ---------------------------------------NPFLFQEGKLFEMTRSGAIDMTKRSYADESLHFFQIGQDSNEETIS-----------------------------------------EDLKEGATGAEPPQTETTSESLELSGPKEAMD--------DEGELVPDDVSEE-----------------------------IEDLPASDADLDS----KVVISASTETPTKEAVSTVAEEPATMQWSDS-----------LSTVKQTSCPTFPEPVG--QLDFSTVTRSVYSDRD-------------------------------------DES----PDSSPEEQKSVIEIP--------------TAPMENVPSAEIKP-----------QIPIRTLPTSVS-------------------------------------------------APPSAEDESAFSDDFPSGLDG----------------------------ESEEDGAKPKS-----KIPIKAPPQRTEWHPSHPDISLQK-----------------------------------------SGVPQGQDVLSRGPDGRSKSESDASSLDAKTKCPVKARSYIETETES---------------RERAEGFESESEEGATKPKLFASRLPVKSRSTSSSSRTGTSPTRESREHFFDLYRN----------------------SIEFFEEISDEAS-------KLVDRLTQSEREQEPPSDDESSSALEVSVIENLP----------------------------------PVDTEHSAPEDIFDTRPIWDESIETMIERIPDENG------HDRAEDPQDEQ-------------------ERMEERLAYIADHLGFSWTELARELDFTEEQIHQIR-----IENPNSLQDQSH---------------------------------------------------------ALLKYWLERDG----------KHATDTVLIECLTKIN-RMDIVHLLETNTEPLQERMGRTYAEMEQTITLDHSEGFSVLPEELCAVKEKK--EQEASKESESSDHPPMVS------------------------------EEDISVGYSTFQDCIPKTEGDSPAAALSP-QMHQESVQQDFSGKMQD---------QQEYY-VTTPGAEVEDTQKATVIPDSLCKTPEDISTPPEEAKPCLQTPVA------------IEHA-SPIVQEPEE---------------ASEPKEESSPR---------------KTSLVIVESTDDQPQVFEKLDGDAAFQK-------------------GDDMPDIPPETVTEEEYVDENGHTVVKKVTRKIIR-----RYVSSDGTEKEEITMQGMPQEPVNIED--------GDSYSKVIKRVVLKSDTQLSEVTLSEPSIVSGTSQFQAEPVEGRRVSKVVKTTMVHGERMEKSLGDSSLATDLPSAK--------EDFEEVQKEA----LVHFVFVFLSCLLCVCFMCISWLLWVQKENHLSLLHFMHRSMDGVRVTQKTRFPS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C8R3-1", "uniprot_id": "ANK2_MOUSE", "id": "Q8C8R3-1", "name": "Ankyrin-2", "aln": "-------MMNEDAAQKSD--------------SGEKFNGSSQRRKRPKKSDSNASFLRAARAGNLDKVVEYLKG--GIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERKAPLLARTKNGLSPLHMAAQGDHVECVKHLLQYKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNTVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADRDAYTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVT--EEVTTTTTTITEKHKLNVPETMTEVLDVSDE------------------EGDDTVTGDGGEYLRPEDLKE-LGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSHASYLRDSAMIDDTVVIPSHQVSALAKEAERNSYRLSWGTENLDNVALSSSPIHSG------------FLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLG---------------------------------PVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNG--MDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVSQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNG----FGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVAFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFSEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRG-LVHQAICNLNITLPIYAKESESDQEPEEEIGMTSEKN-DETESTETSVLKSHLVNEVPVLASPDLLSEVSEMKQDLIKMTAILTTDVSD----------------------------KAGSLKVKELAKAGEEEPGEPFEIVERVKEDLEKVNAILRSGTCMRDEGRARSSQSER-ELEEEWVIVSDEEIQEAKQHAPVEIDEHPCIEVRVDRETKAKVE--KDSTG-------------------------------------------------------------------------------------LVNYLTDDLNSYTSPHEKKPHTAPEKSGETSQASAVGKSSESNKGKATSAEEKQSAQKQLKPGLAIKKPVRRKLKEKQKQKEESSQSSEEKTELKKGSSEESVD--------------------------------EDRGLVP-EPLPTAKATSPLIEETPIG-----SIKDKVKALQKRVEDE-----QKGRSKLPVRVKGKEDVPKRTTPRTHPAVSP-SSKS------STSSK-------------------------------AERHSSLSSSAKPERHTPVSPSSKNEKLSPVSPSAKTER-------HSPVFSG-KPEKHSP----------GSPSTKNERHSPVSS-------LKTERHTPGSPSGKTDKRPPVPSSGRTEKHPPVSPG-------------KTEKHLPG--SPSIRTPEKPAPGSATGKHEKHLPVSP-GKTEK----------------------------------------------------QPPISPTSKTERIEETMS--------------VRELMKAFQSGQDPSKHKTG----------------------------------------LFEHKSAKQKQPQDKSKSRVEKE---KGHTVTQREVTQRETQRIESQTAKR----------------------------------------------------------------GQRFQVSAATESRRFRSTTITVGLRMEDPVRERFERTPIIKTPEVVP-------SVAAEESHRGSE----KIVDEQGD-----------------------------------------------------------------------------------------------MDFQISPDRKTSTDFSEVIKQELEDNDKYQQFR--------------------------------------------------------------------LTEDTEKAQVHLDQVITSPFNTAFP--LDYMKDEFLPALSLQSGALGGSSESLKQEVIAGSPCSSLMEGTPQISSEES-------------YKHEGLAETPETSPESLSFSPKKSEEQIG------EAKETTKVGTPTDIHSEKELPITNDITDSSQKQGAGVTRGSEPSTEHSQKEVTQDPHKDVCSK-QDGCPESQSVSLA---SEVFTEKGSCGESQLPLVSSAFKTQSESETQESLTPSEVTKPFPPSDASVKTAEGTEPKPQGAIRSPQGLELPLPNRDSEVLSPMADESLAVSHKDS-----------------LEASPVLEDNSSHKTPDSLEPSPLKESPCRDSLESS------------------------------PVEPKMKAGILPSHFPLP----AAIAKTDLVAEVASMRSRLLRDPDGSAEDDSLEQTSLMESSGKSP---LSPDTPSSEEVSYEVTPKPSDS---------------------------------------------STPKPAVIHECAEEDDSENGEKKRFT-PEEEMFKMVTKIKTFDELEQEAKQKRDYKKEPRQDGSSSASDPDADYSAEVNDEK----------------------QMAGTEGEGEVPVLVTSENRK----------VSSSSS------------ESEPELTQLSKGADSGLLTEPVIRVQPPSPLPSSIDSNS----SPEEAT-----QFQPIVPKQYTFKMNEEIQEEPATSE-DKDCKSHLAEDSQTHSADAADGS--DGDLNRETT-QPETCDGHGCETVSPSNSATPVSLG-----------VQSPEHKDVDKPLAIDKDSLAHQDTCE-------NDREEREFD-----------------------------PSGVESTQADLPNE-SSSLSS--RCAIPEGNESAKEIASPSSPVKVEV--------------------------------TITDQALESMPEDCPIQDSSTTMQTERFAMDVPVSELAETDENS----DPQIISPYENVPSSSFFSAEPSKIQTDTCHSTVVHSPEVYSVIIRSSPEDVVVTNSSNRTVSGEESHCESHDLE-----------------------------------------TESEQKSALWAAQSDAP------------------PLAVAPTASDAASV------------------TGEQASKVIITKTDADADSWSEIRE--------DDAAFEARVKE---------------------------EEQKIFGLMVDRQSQGTTPDTTPARTPTEEGTPTSEQ---------------------------------------NPFLFQEGKLFEMTRSGAIDMTKRPYADESLHFFQIGQESNEEAIS-----------------------------------------EDLKEGATGAEPPQTETTSESLELSEPKEAMD--------DEGELLPDDVSEE-----------------------------IEDLPASDANIDS----QVIISASTETPTKEAVSTAVEEPPTTQRSDS-----------LSTVKQTPRPAVPGPVG--QLDFSPVTRSVYSGQD-------------------------------------DES----PESSPEEQKSVIEIP--------------TAPVDNVPSAESKP-----------QIPIRTLPTLVP-------------------------------------------------APPSAEDESAFSDDFPSSLDE----------------------------DSKEGGAKPKS-----KIPVKAPTQRTEWQPSPTDIPLQK-----------------------------------------TAVPQGQETLSRAPDGRSKSESDASSLDAKTKCPVKARSYIETETES---------------RERAEGFESESEDGATKPKLFASRLPVKSRSTSSSGRPGTSPTRESREHFFDLYRN----------------------SIEFFEEISDEAS-------KLVDRLTQSEREQEPPSDDESSSALEVSVIESLP----------------------------------PVDIEHSAPEDIFDTRPIWDESIETMIERIPDENG------HDRAEDPQDEQ-------------------ERMEERLAYIADHLGFSWTELARELDFTEEQIHQIR-----IENPNSLQDQSH---------------------------------------------------------ALLKYWLERDG----------KHATDTILIECLTKIN-RMDIVHLLETNTEPLQERMGRSYAEIEQTITLDHSEGFSVLPDELCAAKEKK--EQEASKESESSDHPPMVS------------------------------EEDISVGYSTFQDCLPKTEGDSPAAALSP-QMHQEPVQQDFSGKTQD---------QQEYY-VTTPGAEVEDPQKATAVPDSLCKTPEDISTPPEGTKPCLQTPVT------------SERG-SPIVQEPEE---------------ASEPKEESSPR---------------KTSLVIVESTDDQSQVFERLDGDAAFQK-------------------GDDMPDIPPETVTEEEYVDENGHTVVKKVTRKIIR-----RYVSSDGTEKEEVTMQGMPQEPVNIED--------GDNYSKVIKRVVLKSDTQQSEDNNE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q01484-4", "uniprot_id": "ANK2_HUMAN", "id": "Q01484-4", "name": "Ankyrin-2", "aln": "-------MMNEDAAQKSD--------------SGEKFNGSSQRRKRPKKSDSNASFLRAARAGNLDKVVEYLKG--GIDINTCNQNGLNALHLAAKEGHVGLVQELLGRGSSVDSATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGANQSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMELLVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNGALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAHYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDKVNVADILTKHGADQDAHTKLGYTPLIVACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTANGNTALAIAKRLGYISVVDTLKVVT--EEVTTTTTTITEKHKLNVPETMTEVLDVSDE------------------EGDDTMTGDGGEYLRPEDLKE-LGDDSLPSSQFLDGMNYLRYSLEGGRSDSLRSFSSDRSHTLSHASYLRDSAVMDDSVVIPSHQVSTLAKEAERNSYRLSWGTENLDNVALSSSPIHSG------------FLVSFMVDARGGAMRGCRHNGLRIIIPPRKCTAPTRVTCRLVKRHRLATMPPMVEGEGLASRLIEVGPSGAQFLGKLHLPTAPPPLNEGESLVSRILQLGPPGTKFLGPVIVEIPHFAALRGKERELVVLRSENGDSWKEHFCDYTEDELNEILNG--MDEVLDSPEDLEKKRICRIITRDFPQYFAVVSRIKQDSNLIGPEGGVLSSTVVPQVQAVFPEGALTKRIRVGLQAQPMHSELVKKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKASSDVMLNG----FGGDAPTLRLLCSITGGTTPAQWEDITGTTPLTFVNECVSFTTNVSARFWLIDCRQIQESVTFASQVYREIICVPYMAKFVVFAKSHDPIEARLRCFCMTDDKVDKTLEQQENFAEVARSRDVEVLEGKPIYVDCFGNLVPLTKSGQHHIFSFFAFKENRLPLFVKVRDTTQEPCGRLSFMKEPKSTRG-LVHQAICNLNITLPIYTKESESDQEQEEEIDMTSEKN-DETESTETSVLKSHLVNEVPVLASPDLLSEVSEMKQDLIKMTAILTTDVSD----------------------------KAGSIKVKELVKAAEEEPGEPFEIVERVKEDLEKVNEILRSGTCTRDESSVQSSRSERGLVEEEWVIVSDEEIEEARQKAPLEITEYPCVEVRIDKEIKGKVE--KDSTG-------------------------------------------------------------------------------------LVNYLTDDLNTCVPLPKEQLQTVQDKAGKKCEALAVGRSSE-KEGKDIPPDETQSTQKQHKPSLGIKKPVRRKLKEKQKQKEEGLQASAEKAELKKGSSEESLG--------------------------------EDPGLAP-EPLPTVKATSPLIEETPIG-----SIKDKVKALQKRVEDE-----QKGRSKLPIRVKGKEDVPKKTTHRPHPAASP-SLKSERHAPGSPSPK-------------------------------TERHSTLSSSAKTERHPPVSPSSKTEKHSPVSPSAKTER-------HSPASSSSKTEKHSP----------VSPSTKTERHSPVSS-------TKTERHPPVSPSGKTDKRPPVSPSGRTEKHPPVSPG-------------RTEKRLPV--SPSGRT-DKHQPVSTAGKTEKHLPVSPSGKTEK----------------------------------------------------QPPVSPTSKTERIEETMS--------------VRELMKAFQSGQDPSKHKTG----------------------------------------LFEHKSAKQKQPQEKGKVRVEKE---KGPILTQ-----REAQKTENQTIKR----------------------------------------------------------------GQRLPVTGTAESKRG-VRVSSIGVKKEDAAGGK-EKVLSHKIPEPVQ-------SVPEEESHRESEVPKEKMADEQGD-----------------------------------------------------------------------------------------------MDLQISPDRKTSTDFSEVIKQELEDNDKYQQFR--------------------------------------------------------------------LSEETEKAQLHLDQVLTSPFNTTFP--LDYMKDEFLPALSLQSGALDGSSESLKNEGVAGSPCGSLMEGTPQISSEES-------------YKHEGLAETPETSPESLSFSPKKSEEQTG------ETKESTKTETTTEIRSEKEHPTTKDITGGSEERGATVTEDSETSTESFQKEATLGSPKDTSPKRQDDCTGSCSVALAKETPTGLTEEAACDEGQRTFGSSAHKTQTDSEVQESTATSDETKALPLPEASVKTDTGTESKPQGVIRSPQGLELALPSRDSEVLSAVADDSLAVSHKDS-----------------LEASPVLEDNSSHKTPDSLEPSPLKESPCRDSLESS------------------------------PVEPKMKAGIFPSHFPLP----AAVAKTELLTEVASVRSRLLRDPDGSAEDDSLEQTSLMESSGKSP---LSPDTPSSEEVSYEVTPKTTDV---------------------------------------------STPKPAVIHECAEEDDSENGEKKRFT-PEEEMFKMVTKIKMFDELEQEAKQKRDYKKEPKQEESSSSSDPDADCSVDVDEPK----------------------HTGSGEDESGVPVLVTSESRK----------VSSSS-------------ESEPELAQLKKGADSGLLPEPVIRVQPPSPLPSSMDSNS----SPEEV------QFQPVVSKQYTFKMNEDTQEEPGKSEEEKDSESHLAEDRHAVSTEAEDRS--YDKLNRDTD-QPKICDGHGCEAMSPSSSAAPVSSG-----------LQSPTGDDVDEQPVIYKESLALQGTHE-------KDTEGEELD-----------------------------VSRAESPQADCPSESFSSSSSLPHCLVSEGKELDEDISATSSIQKTEV--------------------------------TKTDETFENLPKDCPSQDSSITTQTDRFSMDVPVSDLAENDEIY----DPQITSPYENVPSQSFFSSEESKTQTDANHTTSFHSSEVYSVTITSPVEDVVVASSSSGTVLSKESNFEGQDIK-----------------------------------------MESQQESTLWEMQSDSV------------------SSSFEPTMSATTTV------------------VGEQISKVIITKTDVDSDSWSEIRE--------DDEAFEARVKE---------------------------EEQKIFGLMVDRQSQGTTPDTTPARTPTEEGTPTSEQ---------------------------------------NPFLFQEGKLFEMTRSGAIDMTKRSYADESFHFFQIGQESREETLS-----------------------------------------EDVKEGATGADPLPLETSAESLALSESKETVD--------DEADLLPDDVSEE-----------------------------VEEIPASDAQLNS----QMGISASTETPTKEAVSVGTKDLPTVQTGDIPP---------LSGVKQISCPDSSEPAVQVQLDFSTLTRSVYSDRG-------------------------------------DDS----PDSSPEEQKSVIEIP--------------TAPMENVPFTESKS-----------KIPVRTMPTSTP-------------------------------------------------APPSAEYESSVSEDFLSSVDE----------------------------ENKADEAKPKS-----KLPVKVPLQRVEQQLSDLDTSVQK-----------------------------------------TVAPQGQDMASIAPDNRSKSESDASSLDSKTKCPVKTRSYTETETES---------------RERAEELELESEEGATRPKILTSRLPVKSRSTTSSCRGGTSPTKESKEHFFDLYRN----------------------SIEFFEEISDEAS-------KLVDRLTQSEREQEIVSDDESSSALEVSVIENLP----------------------------------PVETEHSVPEDIFDTRPIWDESIETLIERIPDENG------HDHAEDPQDEQ-------------------ERIEERLAYIADHLGFSWTELARELDFTEEQIHQIR-----IENPNSLQDQSH---------------------------------------------------------ALLKYWLERDG----------KHATDTNLVECLTKIN-RMDIVHLMETNTEPLQERISHSYAEIEQTITLDHSEGFSVLQEELCTAQHKQKEEQAVSKESETCDHPPIVS------------------------------EEDISVGYSTFQDGVPKTEGDSSATALFP-QTHKEQVQQDFSGKMQDLPEESSLEYQQEYF-VTTPGTETSETQKAMIVPSSPSKTPEEVSTPAEEEKLYLQTPTS------------SERGGSPIIQEPEE---------------PSEHREESSPR---------------KTSLVIVESADNQPETCERLDEDAAFEK-------------------GDDMPEIPPETVTEEEYIDEHGHTVVKKVTRKIIR-----RYVSSEGTEKEEIMVQGMPQEPVNIEE--------GDGYSKVIKRVVLKSDTEQSEDNNE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QDK6-1", "uniprot_id": "A0A8M9QDK6_DANRE", "id": "A0A8M9QDK6-1", "name": "", "aln": "-------MAHAAAHLKKARELEQPPEIKALAKARERRRRHKERAERKRKSDSNTSFLRAARAGNIEKVLEFLKS--GQDISTCNQNGLNALHLAAKEGHVELVEELLERGAAVDSSTKKGNTALHIACLAGQKEVAKLLVKKTADVNSQSQNGFTPLYMAAQENHLDVVRYLLENGGNQSMATEDGFTPLAIALQQGHNQVVSLLLEHDTKGKVRLPALHIAARKDDTKSAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMIALLLDRGSQIDAKTRDGLTPLHCAARSGHDSAVEILLEKGAPILARTKNGLSPLHMSAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKKANPNARALNGFTPLHIACKKNRVKVMELLVKYGASIQAITESGLTPIHVSAFMGHLNIVLLLLQNGASPDVCNIRGETALHMAARAGQMEVVRCLLRNGALVDAMAREDQTPLHIASRLGQTEIVQLLLQHMAHPDASTTNGYTPLHISAREGQVETAAVLLEAGASHSLATKKGFTPLHVAAKYGSQDVAKLLLQRRALLDDAGKYGLTPLHVAAHYDNQQVALMLLDKGASPHATAKNGYTPLHIAAKKNQTRIASALLQYGAETNALTKQGVSPLHLASQEGHTEMAALLLERGAHVNAATKSGLTPLHLTAQEDRVQAAEILAKHDANIDQQTKLGYTPLIVACHYGNVKMVNFLLQNGANVNGKTKNGYTPLHQAAQQGNTHIVNVLLQHGAKPNAVTMNGNTALSIAKRLGYISVVDTLKVVT--EEIITTTTMVTEKHKLNVPETMTEVLDVSDEEAQHQTEEELFTEVYMEIEGEDTMTGDGGEYLRAEDLRE-LGDDSLPG-HYLDGMSYTHN-------------LDRSHETPSHLAYRGEGILIEDMIASHQINKVSAFREHEKDSYRLSWGAEHLDNVVLTSTLLQSGQSTPCLDHDNSSFLVSFMVDARGGAMRGCRHNGLRIIVPPRKCSAPTRVTCRLVKRHRLASMPPMVEGEGLAGKIIEVGPTGAQFLGKLHLPTAPPPLNEGESLVSRILQLGPPGTKFLGPVIVEIPHFAALRGTERELVILRSETGESWREHHCEHTEEELNQILNG--MDEELDPPEELEKKRICRLITRDFPQYFAVVSRIKQDSHLIGPEGGVLSSTLVPQVQAVFPEGALTKRIRVGLQAQPIGEDLVRKILGNKATFSPIVTLEPRRRKFHKPITMTIPVPKSPTSDGTN--------STPTLRLLCSITGGTTPAQWEDITGSTPLTFINQCVSFTTNVSARFWLIDCRQCQESVNFSSQLYREIICVPYMAKFVIFAKTLDPIEARLRCFCMTDDKMDKTLEQQENFTEVARSRDVEVLEGKPIFADCFGNLVPLTKSGQHHVFSFYAFKENRLSLFIKIRDSTQEPCGRLSFTKEPRTYRT-LNHNAICNLNICLPVYSKDSDSDQDADEESEKTHEKYYDGSDSTELSMLQ--IIHDPATLASPDLLSEVSDMKQDLIKVSVLLTSEKSS----------------------------SSN--TGKRLNQAADEEVDEPFEIVEKVKEDLEKVEVILREGTVDEIGAIGRSVTIDD----EEWVLLSEQDVDEFKSKNITEVQETLVQEVRIIRDTLSSSSPKRDMTG-------------------------------------------------------------------------------------MVSYLSNDL-------EQCLQEMPVPSSHSHDVDIVQESFK----------EVVLARGKHRP-AEIKKPARKKRKERE---FASGSSEDDLERMSRSQSEESLD--------------------------------EDAIIGGSEYVFGSVPVSPKVVETPIG-----SIKDKVKALQKKVEEEKVTDSQKWNSQKVSSSQRTSYIAETEKSYQYPPKSPKSPRSQTERLEETMSVREL-----------------------MKAFQTGQDPSKSKSGLFEHKAITTVTSESSDMTQVTTAFDNQMTVTTQHLHEGIITTVTSEASSSDVVQVPVAYNAQTAISTQHLQEKFA-------VENEILQELSTDPNTILHKPVIGDGESLSTTTAQNKDDQAVTTKTIFNLKEEKDLDDR-LTKLKTHQHEKPSQEPGRFETEKHVSSELLGNKE------------------------------------------------IVMLPSENQSSDVMLIAPTYDGQ---MAVTTKNEQERDLLIVHSEATSSDVIQVPT---------------------------------------KFDHQMIVSSQHLQVVNSKILQEPSIDPNTVSSQHLQVAESKILQEQSIDPNTVS------------------------------------------------------------SQPLQVAESKILQEQSIDPNTVTSQHLQVVEGKILQEPSIDPNTVAPQHLQVVESKILQEPSIDPNTVQLKPVIGDGDALPTTISSSWSIKNKDEEVVTSKIVLSFEEVHSPEDLLVKPRTIDQHGKPSKKTGSFETEEQQMTSELLRNEDMGLKPEKMY-YEDNIYQNRRLSVEPQISPDRKPSEDFSADIKAELEDNPEYLLFRRTSGGAS----------------------------------------------------KRHMMFSDALSSDDEQIQQMAVDPSNSNIITAFA--TAMVQGESLLQSEVDDRALEGSPDGDKHEAWADSPGGSIGLRTPHSSSGDS-------------EKHEGLAETPQKSPEILVLSSSTTTKETEDQG-NQETTHKTKVLISHERREMGEDDKLYSVTSKISETESTSPHDFETESPSLFTETELPSNKDSKIRSSSSSTRTETLSFAN---TNTLIYDTIKGVKWDSEASAHNMKSDSSSRDSVK-LIKTDVITKSEKILEQSQDTPDRP---------------YSLDDLQPATMSDFKIVCRTDS-----------------LETTPIREDGSSQKTPDSIEPSPTKESPCQDSLEGS------------------------------PTGQESGQLSFTEKVFSTNQAFVSDSRENIDIEIGSEQDIQLDSESSQESHETQDMQCLSITLDQRENLLESEDLHDFDVLQRQFTPEEEMF---------------------------------------------KMAAKIKTFDEMEKDAKVKKVKFDFEQPKEERPPHYSSLDTVLTKESEDKYLENLNESGLLYSSLSDDDYYSPESHKVSGQTSEVLETPDKH-----EQNHTHLKTVDLQACTDIPYMQKHVDNKEDYDQLHSEYHSKTTD------------ETKTEIELITTPVESKMGFEPDTDADSVSPVESTTSEKVNEPISPIDIVGATAANDLQDESQLYLCDYEEKPGETPGSSPIDLVPWSAGVEDDEAFDAQIEDEE--QKILAFSTDRQSHGTTPDTTPGRSPTEEGTPNPFL-----------FQEGKLFEMTRGGAIDMTKRTMEEEEERLAFFPINEDPSEEFERVNFNISESDEVASFEL------------PSNDSVNQNTIPEELEAKSDSLNKTGTKSVQPEHLEPIEFSIQNKPSS--------------------------------PTDNNVHEDTLISNVDTTTYTVTQTIHSEQDLESSDSSVEDEHISVVEMPISTQVSTIFSSASVHTTREDQFQTSSLMSTSFKDIAAEIEDTTSKPKIAVKAASFDQILEPGDSIEQNLRPK-----------------------------------------SEADTGDSEWSMSVAEDPINIDRIYTIPKTSFSQMPVSPTETPPPYTVS------------------SQPKLPAEFIQNLDSSNTKCDETKR--------DKSSTDLGIDSNLKAIRPPSVGDDV------------FEARPNWEDCVETQMQRISDSTTPEQSKVDWHEDADRKEETLAIIADL--------------------LGFSWTELAKELEFNEDEIQHVRAENPNSLQEQSHALLQRWVEREGKHATEDTLIKRLTKINRMDIVHLIEI---------------------QMHKSIQEQTSRTYAEIERTLDHSEALSSVQEDVDSLRVVRRVETSQRHPPAVSEEDLSVASLLDIPSWAETMGNIHSESIHGDLMEELEINQDSFTNPWMFHEIKTESAKEVADEEVSTASEEENQAQFDLSDHKNACLPSSQVSSKSQSEDHQHSTKTSQNVFDFSQVSIARFSSSENSVLSTAEPGQAVPDLLQHTSPVTLEEETQLQEPMYQDESSACADQVSPVYEKSDLESSEKSLDAQLFESNGFSDTMQSLSWRENKPSEADELTPENNQISQNISPSISPGAVVREADEVLSRSDEVNPVVSSVTPDLIKGSPESDQVFFTPDKFSDMNPVPSMQSHIAVEQSFVQSCSE----------------------------VDSASLESPIYNDNTVLIQEQSDTNTYSQELSEPDVDTRKEQQTLAHEQELYLQKTEALGDHCNDTEDRNCPGKAEPQLDSTTDPFIDDSQDFRNELLSQSETDPDTWIERGTAQLRQTSPFRSDLSQQP--EACMPCQHFDIREKSLELETESNKQSVSHEIMTARGLKRPQSESLLSSASQQIEKKHTERCLSESSEPLVLTLKINLALEKAVSQEEILALPLSQDGSDKALPPKEFKRQLSDSVSSRAKSQEKHSARCLSGSSETLMLDELKKTFQ----------------------PEQPLSDHTVNSEVSVSKLTAESQETFTGEQQSVIEETLVESPKSQIDLSEHAQFFQSETG----------------PDMWIQRETAQMSETSSLCSSDLSPQTPETVINCQHFREKSSELESTSAIKSASKGAVEAKGLRRPQSESFISGATQQSEEKRTDRCFSESSQPLVLTLNIDPALEKVVSQEAILALPLSQDGNTLPYLKDSERLLSDSVMHGSISQKKEGNNSGPCLTDSSEDLVFNMSSSPEKIKKPVQPKQPTSDQTVNNEVSVLSVTASTQDTFIGEQQSAVKETSLDSPK--------------------------FQTDLSENYELKASEMPKADKPKLVGVISTDQQHEDSDLESFFDCKQTISDYSEAEDDEHWKGTMTLNDQFLTSTIHELQQNTNVRSPSSLVAPDESPRWSVQSSDS------------EDFEDSQIIHEPSDEGEVRDFSSKASLKTSAETPQELPPRGGAEYNDDDDLRREIEDALGVLSDSSDEDVLTTRIVRRRVIIQ-------------------GDDVPDISPQSVTEEQYTDAQGNLVVKKVTRKVIR-----RCVSSDGVETEQLRVEGSAQQPVHVAP--------GDSYSKVMKRTVLKSEGHETEVTFHEKDSISAS---RGESAAGQEVRQMVQTTVVHGEQLEKHEGNPFLARDLPSAR--------DDFTQALNYFGGFRKVQIPRVVEQEILQPDGSVIRRTRMQKSRTHRRSAVRDAGGQKRVCVEQIDDRSEPHDNLQHHLHHLIHRYCAQND-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9MRX4-1", "uniprot_id": "M9MRX4_DROME", "id": "M9MRX4-1", "name": "", "aln": "-------------------------------------MVTENG----AQGDGNTSFLRAARAGNLERVLEHLKN--NIDINTSNANGLNALHLASKDGHIHVVSELLRRGAIVDSATKKGNTALHIASLAGQEEVVKLLLEHNASVNVQSQNGFTPLYMAAQENHDAVVRLLLSNGANQSLATEDGFTPLAVAMQQGHDKVVAVLLESDTRGKVRLPALHIAAKKDDVKAATLLLDNDHNPDVTS--------KSGFTPLHIASHYGNQNIANLLIQKGADVNYSAKHNISPLHVAAKWGKTNMVSLLLEKGGNIEAKTRDGLTPLHCAARSGHEQVVDMLLERGAPISAKTKNGLAPLHMAAQGEHVDAARILLYHRAPVDEVTVDYLTALHVAAHCGHVRVAKLLLDRNADANARALNGFTPLHIACKKNRLKVVELLLRHGASISATTESGLTPLHVAAFMGCMNIVIYLLQHDASPDVPTVRGETPLHLAARANQTDIIRILLRNGAQVDARAREQQTPLHIASRLGNVDIVMLLLQHGAQVDATTKDMYTALHIAAKEGQDEVAAVLIENGAALDAATKKGFTPLHLTAKYGHIKVAQLLLQKEADVDAQGKNGVTPLHVACHYNNQQVALLLLEKGASPHATAKNGHTPLHIAARKNQMDIATTLLEYGALANAESKAGFTPLHLSSQEGHAEISNLLIEHKAAVNHPAKNGLTPMHLCAQEDNVNVAEILEKNGANIDMATKAGYTPLHVASHFGQANMVRFLLQNGANVDAATSIGYTPLHQTAQQGHCHIVNLLLEHKANANAQTVNGQTPLHIARKLGYISVLDSLKTITKEDETAAAPSQAEEKYRVVAPEAMHESFMSDSE---------------EEGGEDNMLSDQPYRYLTVDEMKS-LGDDSLPIDVTRDER-----------------MDSNRMTQSAEYASGVPPTIGEEVISPHKTQVYGSSPKATVDGVYIANGSGHDEPPHVGRKLSWKS------------FLVSFLVDARGGAMRGCRHSGVRMIIPSRSTCQPTRVTCRYVKPQRTMHPPQLMEGEALASRVLELGPCSTKFIG---------------------------------PVVMEVPHFASLRGKEREIIILRSDNGETWREHTIDNSEEIIHDVLQQCFEPEEIAQLEEQAGNHVCRFVTYDFPQYFAVVSRIRQEVHAIGPEGGMVSSTVVPQVQAVFPQGALTKKIKVGLQAQPVDPDLTAKLLGRGVAVSPIVTVEPRRRKFHKAITLSMPAPKAHSQGMINQYSGN----TPTLRLLCSITGGPSRAQWEDVTGSTPLTFVNDCVSFTTTVSARFWLMDCRNISDATKMATELYKEVIHVPFIAKFVVFAKKVEPFEAKLRVFCMTDDREDKTLEKHELYTEVAKSRDVEVLEGKPQYIEMAGNLVPVTKSGDQLQVQFKAFRENRLPFTVRVKDQHADIVGRTLFMKEPKVAKGEPPQQPICILNIVLPEAVIPDSTTAFSDRVTSAYRTSMFSLSKHQNDHYIGDIRIVDLSNLLGKDWIQLAPEIGINGEEIDEIINQNTDSIARQAQSMIRLYKDKPNYDILSLETALKNIGRDDIMKKCKSGRLSHSREFDEADLMKNSESVEELVRRESKRIQQINEREEVKYSA----EEKEVEESESDEEAAKRTVAERREKIVKRLSIERSIPASTQ-KKEITREITEIKRKSLIEDKKAHHESEILMQLPADNVIIKTTTVPDQVIKMKMGKMDSTEVSKSEFDKELTHKFKTSGRSSEEEDQPSYPDQTDKIVQDISAAEKKEKDGVTFSRVTTITRQEARDITEDFLEIEKRSQLPATSTTATVHEKFVEEIKEKTSPLASVPQETVKEVQQVISEVTEIASKKVENIISSFESSKSVDATTVLPTQPSVESTKVSETIKNLEDAKAVSAEQVKTVHVVESSSIEETIAEFEAKKVKYDFHGGEPKTQIPKFTRKPSDDSMKPTAAPRATVESETESVLETKAEKPISKIPVKTIPTEAQKVSEVDARKITQDFLQGEKLAAEPKPSPAASKIPKVEPRKSVDKQVDRESKILDDVVASTATIMTAGLGDEQLKDQLVDHSEIIAKSETVAEKVTELLDTFHKIEEKVTKSEKTSEISSKVEELVKIEEKPLSQVQPKEDKVAEKVAEVIETFHKIEEKITTADARELTRDFLSMEQQNQLPSMPQAAEKPLESSLTSTSASEPESIVTVKPSPPASKIPVVEPRKIVFDESTKPLIEPEPVKTTEKKPLNERQLTADFLSMEQQTQLVSEPAKSLVEEVMKSAEQMVEQPKQQKSLNERQLTEDFLLMEQQTQLPSDIVKPTDKLIDGIESAAPVGDEASPFHTPKLTTSVVTQEPQQLASEYDSDTFGKQATIPLGDSKIDQGLIAPVSMEPRKSLTDAEFCKSVGETITKKMSVGVIEISDELKKIESEIPHSQTPPPTPSDNKTDKQNEEPELISLERDYLADTVTTLHTTTESTLERVSAITKIEHFSVHNVKSETFTRTDEPDKLLHSVVAPPDIQKLYSQDTTSFTEMSTSSQTPKMTTTTTMTAQIDRTKVDLTIPGQDQQKQKDLKEQSAVVVDAKAETEKTASDREYLEQIMGCGDVRRKIMRLESSCSTESLESVGKSSTVTPKYIGDNVPVVREVVQSMEDKICSTVVSAIPFTVQKRKPHDDDKEPNIVELEKQILTPADLALEKIFKCEPPSEVVKISPIEAMSLGLKEIDEEVCEKVCEKRKSFVVAEDLCETEKTLTEQVIDLNRQVDQVPARVFTETIERHLDLEDRDVIEALPKVREVVQDIERKYPAASLEAKPFSPRKRVTPDRKVDVSSLEQQILTDADLILDGLGSKCVPEQKVQSPIFSSNKASSSTENLEDICEKKCSKRTISDMTKVFERQEDPTTMPSIKDVKSTTAKFLESESGKFAITESIQHFNAKGSINKEVAGIEKGQIRFLKDCDTQEFPIETNLDTKLVEFPKITHTLERLHSISKTDIADTKKVVHESSEFKSKLDKLVHKTEQTDNQNPDKFKFPTQDNFDELQTQKSLTSELVTMTDSSEYKFPPEGKSILGKEPIESESDEELDNLNKICKLQLLSKIEQSSFIDTTEIANTEKREITKFPTTNDSHSDLFSKSRATLKTQSGEKTHCTHFTETISDKNYNSFSDTSFLLNSVTASADKSPLHPEEKTKSPEKKDEKVLAQPDDNFKSVIETDKPSPKEYSDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPVKIDEEVLAKPGGSSKSVVETDKPSPKEYSDDETEDEIDFPKPQDKPFKEATPSVTPVSTIPDVKAIDFVSFKAEECSTTIQTNIKLASTSLTTKDTKIVQPIDSLSNLKDDKFPTSVGDKAKSPRESVKPNLKEYSDKEEKPDSHPVSLVTSVTGSGDKSPLHPEEKPKSPEKKDEKILAKPDDSSKSVVKTDKPSPKEYSDDEIEDEIEIPKPLDKPISHPTSLVTSVTGSGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKLKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKLKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDGSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHREEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTYGGDGSPLHPEEKPKSPEKKDEKVLAKSDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDGSSKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKLKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDGSSKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTG---VTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDGSSKSVVETDKPSPKEYSDDETEDEIEIP---KPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPGGSSKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGVDKSPLHPEEKPNSPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDGSSKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTG-------VTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDGSSKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPGGSSKSVVETDKPSPKEYSDDETEDEIDFPKPQDKPFKEATPSVTPVSTIPDVKAIDFVSFKAEECSTTIQTNIKLASTSLTTKDTKIVQPIDSLSN----LKDDKFPTSVGDKAKSPRESVKPNLKEYSDKEEKPDSHPVSLVTSVTGSGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKLPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDETDDEIDFPKPLDKPISHPTSLVTGVTFGVDKSPLHPEEKPKLPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGVDKSPLHPEEKPNSPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPVKIEEEVLAKPDDSSKSVVETDKLSPKEYSDDETEDEIEIPKPLDKPFKEAMPSVTPVSTIPDVRAIDVVSFKAEECSTTIQTNIKLASTSITTKDTKIVKPIDSLSNLKDDKFPTSVGDKAQSPRESVKPNLKEYSDKEEKPDSHPVSLVTSVMGSGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSPKEYSDDETDDEIDFPKPLDKPISHPTSLVTGVTFGVDKSPLHPEEKPKLPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDETDDEIDFPKPLDKPISHPTSLVTGVTFGMDKSPLHPEEKPNSPEKKDEKILAKPDDSSKWVVKTDKPIPKEYSDDETDDEIEIPKPLDKPISHPTSLVTSVTGSGDKSSLHPEEKPKSPEKKDEKVLPKPDDSSKSVVKTDKPIPKEYSDDETDDEIDFPKPLDKPISHPTSLVTGVTFGMDKSPLHPEEKPNSPEKKDEKVLAKPDDSSKWVVKTDKPIPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGMDKSPLHPEEKPNSPEKKDEKVLAKPDDSSKWVVKTDKPIPKEYSDDETEDEIEIPKPLDKPISHPTSLVTSVTGSGDKSSLHPEEKPKSPVKTEEKVLAKPDDISKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGVDKSPLNPEEKPNSPEKKDEKVLAKPDDISKSVVKTDKPIPKEYSDDETDDEIEIPKPLDKPISQPTSLVTGATFGGDGSPLHPEEKPKSPEKKDEKVLAKPDGSSKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGMDKSPLHPEEKPNSPEKKDEKVLAKPDDSSKWVVKTDKPIPKEYSDDETEDEIEIPKPLDKPISHPTSLVTSVTGSGDKSSLHPEEKPKSPEKKDEKVLPKPDDSSKSVVKTDKPIPKEYSDDETEDEIEIPKPLDKPISHPTSLVTGVTFGVDKSPLNPEEKPNSPEKKDEKVLAKPDDISKSVVKTDKPIPKEYSDDETDDEIEIPKPLDKPICQPTSLVTGATFGGDGSPLHPEEKPKSPEKKDEKVLAKPDGSSKSVVETDKPSPKEYSDDETEDKIDFPKPQDKPFKEATPSVTPVSTIPDVKAIDFVSFKAEECSTTIQTNIKLASTSITTKDTKIVQPIDSLSNLKDDKFPTSVGDKAKSPRESVKPNLKEYSDKEEKPDSHPVSLVTSVMGSGDKSPLHPEEKPKSPEKKDEKVLPKPDDSSKSVVETDKPSPKEYSDDETDDEIDIPKALDKPISHPVSLVTSVMGSGDKSPLHPEEKPKSPEKKDEKVLPKPDDSSKSVVETDKPIPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGVDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDENDDEIDFPKPLDKPISHPVSLVTSVMGSGDKSPLHPEEKPKSPEKKDEKVLPKPDDSSKSVVETDKPIPKEYSDDENDDEIDFPKALDKPISHTTSLVTSVTGGGDKSSLHPEEKPKSPEKKDEKVLPKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGVDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDENDDEIDFPKPLDKPISHPTSLVTGVTFGGDKSSLHPEEKPKSPEKKDEKVLPKPDDSSKSVVETDKPSPKEYSGDETDDEIEIPKPLDKPISHPTSLVTGVTFGVDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDENDDEIDSPKPLDKPISHPTSLVTGATFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSSKEYSDDETEDEIVIPKPLDKPISHPTSLVTGATFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSSKEYSDDETEDEIVIPKPLDKPISHPTSLVTGATFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDENDDEIDFPKPLDKPISHPTSLVTGATFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDGEIDFPKPLDKPISHPTSLVTSVTGSGDKSSLHPEEKPKSPEKKDEKVLPKPDDSSKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPVSHPTSLLTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPIPKEYSDDETDEEIEIPKPLDKPISHPTSLVTGATFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDENDDEIDFPKPLDKPISHPTSLVTGATFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDGEIDFPKPLDKPISHPTSLVTSVTGSGDKSSLHPEEKPKSPEKKDEKVLPKPDDSSKSVVETDKPIPKEYSDDETDEEIEIPKPLDKPISHPTSLVTGVTFDGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKSTPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHQTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKSTPKEYSDDETDDEIDFPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPIPKEYSDDETDEEIEIPKPLDKPISHPTSLVTSVTGSGDKSPSLVTSLVTSVTGSGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPSSKEYSDDETEDEIVIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPVSHPTSLLTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKQDDRSKSVVETDKPIPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDRSKSVVETDKPIPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDGSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIDIPKPLDKPISHPTSLVTSVTGSGDKSSLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPIPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETEDEIEIPKPLDKPVSHPTSLLTGVTFGGDKSPLQPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPFSHPTSLVTGVTFDGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTSVTGSGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIDFPKPLDKPISHPTSLVTGVTFGVDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKPIPKEYSDDETDDEIEIPKPLDKPISHPTSLVTSVTGSGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFDVDKSPLHPEEKPKSPDKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVKTDKSTPKEYSDDETDDEIDFPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPSSLVTGVTFGGDKSPLHPEEKTKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPSSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPGGSSKSVVETDKPSPKEYSDDETDDEIDIPKPLDKPISHPTSLVTSVTGSGDKSSLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPSSLVTGVTFGGDKSPLHPEEKTKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPSSLVTGVIFGGDKSPLHPEEKPKSPEKKDEKVLAKPGGSSKSVVETDKPSPKEYSDDETDDEIDIPKPLDKPISHPTSLVTSVTGSGDKSSLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEISKPLDKPISHPTSLVTSVTGSGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIDFPKPLDKPMSHPTSLVTGVTFGVDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFDGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKPIPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKRSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDDSSKSVVETDKRSPKEYSDDETDDEIEIPKPLDKPISHPTSLVTGVTFGGDKSPLHPEEKPKSPEKKDEKVLAKPDNSSKSFTETDKPSPKEHSDGGRKGTGLSSICLKKITPFMTEEITTSIQTNFKSASSIRATLDTQISNPTSEPGQKTLSVTPLIDDQGISQHPGEKLKTISPIAQKFETQQSYLDHHVGVDLVSDIKENRSVQQIVEDTIRAGDAEVQKIVDETLKSVQKTRDIKEQVVDEGRSVEQIVEDTLKNAKYIPNISKEDKLYCPQLKETDAQEVRPVAYFVNLDDEKKSLDPVKKVPVRSQTKKIIKSETGKILDGASAKPMNKSTISKRTLTVREKPKPKPVSPAKTTIVKQTPSRKTINTDKSKLSNKTESRRSVTSSTSTTTSSASATSRVISEIHFERSSSPASSSIFYESQPQGEGSRSTTPRPRVKTDVTRIPYNTSPRSFSPQLKTTKTDKKTVNQTKTTATRSIKELTEKSSKKTERFASQEHVEKRKTPTPSATHRYMQPTLAHSMRYGLSGDGDIGQNVTLTSPKSPAPPKSPTPALTKSTRRTQTITSALTKSTSQITKQKNSIAEMKQAQPRSQIKRGSQSDSKESLIKSTDRLYKRQTSKENKLANVIGSKSQATKSMKTQSANSAKKLVSKTSIETDNKLLKKTTATIQRTKVPISVSSSARTAAKLSKSDDTVKRPQVDNKKPVKRTVSKVSESSGTTTTTTTSTRIVAKSMEPKLQKKMKDTMNESSSNSGSGTTSASGSSNSTRRSVRSVSTVSRKTDKDLTNIRRASGAVVSTSTVRVHREPTATTSAVSTVLVDDDCEVITIRSIKSSDSTKSSTSSSSGSGSNSRKVLTSEVFTKTFGPDKPLEVVYRQPEFDVEHHTIMSVRPPSATSSDQQRCINEFDVSFIDTTDSSLSDSVALPMLGSGDPDRLLAASPGSPKPTRSPLALIEETLRRQQQHHHHQQHHHHSSGAIAAALDPSLSMPVAFGESHLEAEVEVEKGSISKETLHERKVELSNLDTEKISHEIGDVKVGGGDDDSDGDSGDFVARIREEANILVDRVLEESVEIIESQGHQANGHEIAKLDYNSESENYAITCDDIGGVDVIKSPTIESMSGKSFDDNMSFTDEHIHLPLHAQNTSTTMTTTITTQFQQQQSQSAVSSTSAAKDPVAVLESVPVSFPVASSRNQTEDESETRARRIDHKIEKLSTDMDDVSARFDEAFEMSVPEDEISALQGDFSKLSWDESVSPTTNTMADMAQNQITPDNDIQDLIAETGGDLPNSSETDTTPVPPSKESESKTETEPTVVTNAFTTTSHDTPTPKPRVLKASSPVSEGTDSTTIPGPVPKPEIPIDISFDANAPVPKPRAPIKHTEPFENLAALAEQSDSISLRSFELTEDISKTDEPSTELSIRSQLRDIVTTTTVSEDHTESFEPTSEISVDDADTEKSEGAEKTTSFYIGESSRNVIIKTSTRSASVTPQEEEAQGEIGIDAKDISLMKEVSVDSDEANDVFKEFITMKPEDPIAMDSKITRQGSETRNDILEFENADKDKTAEQKLSKVTTEESLTTSTGSSGRAIIEIAPSSSEDPDESSKEIPEIVNTISEKAAASDNFELPLEKSEWETSEKEIPTEGKPKVVHSPQQPQEASMKSTLDRFHVDEILAEEQVTDEHSSSDHKSFKDQTPSELGSSTVPQEYTFAVESEDISSFIGIPEASMQTSTLDSTQPPEGLFDTTIKETLNKQAAMAHYAQDVFGRGERRDDHGSLGFISTGTAEELSSMEEHMAKEEQASLGFISTETAEDFSSMEDYYSEKLAIASVVADEVATEKSLTTSTFEELSSDQSMKPIDVVVHRLKTETSPDSINRWSIPDVDTSSSSESFHRSFDKTQSRPLSSDLDNLVTTTGTGTSSDYQTAREFTTTGRTEGTEYISAVSTLGSSSLDSQSETSANLASIDVSELSETLVASSAEVDAFEAEEMSRLRDLRADDEDSDESVELPGTAGYPSIEQQSLMKRSQEMIFKPKTLDDEPLAVQVAQIEEYPKPKEAERTWGLAYPLEDSKVDSPRESEKGEDILLYHGDPRRSIDESKLASSLDEGSILSVSMSSTSNIDTVVENFDDIIGSAGSSSLTGIEGFQYGHDESIPSASVPEDATFMLEMESKEHSPQDSNASTPPGGESKRRGHKRNESISGDALKNLDKEVALLGEGKESESESDTDPYESEYARQFRSPKERKSKKKKQAAAEMDHSGELEKRPFTPSQLVAEVIVEDSITEELEAEAAMIEERRPSQNMQDYSNIPDIMVTEDIKSPILEEETDEFPEKMLYKVRTEEELHKASDTSVYQKAKAEEKEQDFQRRVQEQYRQKLEELKRAEVGAEYDDRKAPDSPDSFEMVEQPDISDEFVIIEEVAKEANEVDLGGQSIKIKPVKYEQKHDEDVEKIIIKSAPADPKLGSQLYKDDLNFEFEESPPTGASSSSEQQEESDSSETAAANKRWVEMQLTDNQLRYPYDLAGAVLEDIKEEDGEFEVGSSRISSFKDSFSSTPEYDVAARRYHSRGEHDDVSMSSLQEFESLEQAISLENRNRTHQGSTDSSNGSFTRRYVVRHSGSGTAPGDDVSVSSLKDFEGLENACIEAHLIEIKAREEAALLSRSDESNKSNGSDKGATGNVVVTKVTRTVTRTEVVPSSQVESIEALLKQKLEREEGSVQGRVTDIGTTELDTKSKIDSQDSEKDSIDSMEISKSHDMMTSSIESFDISKDATTRSDVDSLEIDKRHSRQESIESFGDEQLDLMTKFVSGGGVTLGDGLTTTTTTTTTSTDADGHEHTVTRVITTITNVGGGIQELPMDESGMSKDVSVDSLNMCVEQTTSSAGTTATYQTSAGNSQMSGSVTSCASSTLMEDSFPGVGGMSSSQMSASFWSHDESTVVEDEGRDLAKKPQQGH", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q0KIE7-1", "uniprot_id": "Q0KIE7_DROME", "id": "Q0KIE7-1", "name": "", "aln": "MTLGDVRVENKIQTR--------------SETCAINGMALDNKNGIIKQNDATISFLRAARSGDIKKVMDFLDCGEISDINSCNANGLNALHLAAKDGYVDICCELLRRGIKIDNATKKGNTALHIASLAGQHDVINQLILYNANVNVQSLNGFTPLYMAAQENHDNCCRTLLANGANPSLSTEDGFTPLAVAMQQGHDKIVAVLLENDVRGKVRLPALHIAAKKNDVNAAKLLLQHDPNADIVS--------KSGFTPLHIAAHYGNVDIATLLLNNKADVNYVAKHNITPLHVACKWGKLSLCTLLLCRGAKIDAATRDGLTPLHCASRSGHVEVIKHLLQQNAPILTKTKNGLSALHMAAQGEHDEAAHLLLDNKAPVDEVTVDYLTALHVAAHCGHVKVAKLLLDYKANPNARALNGFTPLHIACKKNRIKMVELLIKHGANIGATTESGLTPLHVASFMGCINIVIYLLQHEASADLPTIRGETPLHLAARANQADIIRILLRS-AKVDAIAREGQTPLHVASRLGNINIIMLLLQHGAEINAQSNDKYSALHIAAKEGQENIVQVLLENGAENNAVTKKGFTPLHLACKYGKQNVVQILLQNGASIDFQGKNDVTPLHVATHYNNPSIVELLLKNGSSPNLCARNGQCAIHIACKKNYLEIAMQLLQHGADVNIISKSGFSPLHLAAQGGNVDMVQLLLEYG-VISAAAKNGLTPLHVAAQEGHVLVSQILLEHGANISERTRNGYTPLHMAAHYGHLDLVKFFIENDADIEMSSNIGYTPLHQAAQQGHIMIINLLLRHKANPNALTKDGNTALHIASNLGYVTVMESLKIVTSTSVINSNIGAIEEKLKVMTPELMQETLLSDSD---------------DES-CDDLLDHNHYKYMATDDLKANYGQDQKNFDTTN----------------------------TDHDLTDVSVLNKKEILPNEMSCIELTEIGHKPDNVVIAR-----SQVHLG-------------------FLVSFLVDARGGSMRGYRHNGVRIIVPPKACAEPTRITCRYVKPQRVVNPPPLMEGEALVSRILEMSPVDGMFLS---------------------------------PITLEVPHYGTLRKNEREIIILRSDNGESWREHNLYK--DIIG---------EDINQTEEFHSDRIVRIVTQNVPHFFAVVSRVRQEVHVIGPDGGTVFSTAVPQVKAIFPPHALTKKIRVGLQAQSVDLVECSKLLGQGVAVSPVVTVEPRRRKFHKAITLSIPAPKACTNSMVNACYGNGNSSSPTLRLLCSISGGQTRATWEDVTGSTPLSFVRDSVTFTTTVSARFWLIDCRNIIDAGRMATELYSHLAKVPFYVKFVIFAKRISQTEAKFSVFCMTDDKEDKTLEQQEYFKEVAKSRDIEVLQNQIVYLEFAGNIVPILKKGEQLYTKFQPFCENRLSFSAHIKDQEFPHG-RICFMTYPMVGPDEVPLKPLCTLNISVDFKTITN----------HLERDNLHSLNDCINAH-----------------------------------------------------------------------------------GKLNHN----------------------------------------------------------ENIVFGVKEQQVKKIDITKACIMSSD-IKLIH--------------------------------------------------------------------------------------EADVILDDICSHLG--SDWPLLANVLGVSQADIDLVKTEFLLN-----------------------------------DSVKQSMAMLQLWLEHGGILTGNVL-------------------------------------AEALYKIGRSDIVEKS-----------------FKNAEFGTHQPE-----------------------------------------------------------------------------------KVLPTAGIEKDGDYEQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : . ** ::: :. . :. . *********:*:*:: : *** ** :*.:***********.**** :* : *: *.:* ** ************** : ** **.* * :*********:*:****:: *::*** *.:************:*:*.::* ***::* *.*: * :*********:**** ::*.**::. * *:: *::.*:*****.* *: .: *** :*.:*:* ***********:**** ..:. **:: **: ::*****:.***:***:* :..: ** :****:**:************** :*:***** .*:.*******************:*::***:::**.* * *******:**::*** :***: ***: **.*: .:****.**:****.* :::* ***. * *** *** *****:*****: :*: ***** *. :* :.: *:.***:*:*** : . **:* ** . .*********::.*** .*.::***. * * ** .:****** **:* .:. :**.:*:**: *:** .:***.:** ** **::** .* :* *.:****::* *:.:: **:: : .:*.***.:*: ***..* .::** ::.*: . *: ***** :*.*:*: .:*.*::::.*::: :. *******:****: *:*:**.* *:.** * :*:*.* ** .***::*:::** :* . : ** :: .** * * : ..: :: : : .*: :::: *:*. . .: : :. :: . : *****:******:*** **.*:*:*:*.: ***:*** ** :* * ::***.*..:::*:.* . *:. *: :*:**:.:** .***:::***:.*::*:** : : * : *: .:: *::* :.*::******::*: : ***:** : ** *.**:*:** ****:*:******.: *:**. .:.**:**:*********.**:::*.**: :. * :*********:** : * ***:**:***:*:.:.*:***.*******:***: :: :::::* .: **: .***:*** . **:: ******: *****::* : ***:***:***:.: : : **:**: *.*:: .* .* ****.: :::* * * . * :.:* *** : . . .. : . . . .. * .: : : . . : .. : :*: .. : : . . : : : .. .: : .. . . : . ", "identical_positions": 619, "similar_positions": 436, "identity": "4.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111215-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R3Q7-1", "uniprot_id": "PTHD3_RAT", "id": "M0R3Q7-1", "name": "Patched domain-containing protein 3", "aln": "--MISSKVAPGEEEE--QQEAPAEVAP-AEEELRET--EGQLEA----VPPDEASPSWATGPPLERLPPVGQEAPPP----------------------------------RRCHTDCLEAPLSSCFLRLGALVGANPWLFLLGPVLLTASLGTGLIFLPK-EKENLEEQYTPIGSPAKAERRFVQSHFSTNDSYRFSASRTSSETNFASILVVSHRDSLLEPEAFAEVSRLDRAVQALKVVQENGTQILYPEVCAKYSVGCVPPNPLLFSWQQNSSLNLSELTFPIHSVADHLIHLAGFFGGNVLGYATTGNRQRLVESRAMRLLYYLKTEDPEDRERSQAWLTHFLDHFNDMKSDLALEDIEVVYFTSLSRQLEFEATSKTVIPLFHLAYILIILFAVVSCSRLDCIRNKMWVAVFGVFSVAMSVVSGFGLMLHIGVPFVIIVANSPFLILGVGVDDMFIMISAWQKTSLTESVSERLSNSYSKVAVSITITTITNVLAFYTGITSSFRSVQYFCIYTGTTLLFCYFYSITCFGAIMALDGKREVVWSRWLEKPDQ------KYSSFKKFCCVPFGSFPDEHGDDNHPMNLFFRDYFGPFLTTSKAKFIVVLIYIFYIISSIYGCFQVQEGLDLRNLASDDSYITPYFNVEEDYFSDYGPRVMVIVTETVNYWDKDVRQKLDKCMTQFEQNEYVDKNLTEFWLEAYMQYMNNTGNNPNDKNTFMNNIAGFLNFFPVFTYDINVSSSNEITSSRGFIQTIDVSSSSNKKRMLLKLRGIAENCEVPLMVYNQAFIYFDQYAAIIENTVRNVMIASTAMFIVSLLLIPHPVCSLWVTFAIASVIVGVTGFMAFWNVNLDSISMINLVICIGFSFDFSAHISYAFVSSNEPSVNKKSIEALYLLGYPVLQSAISTIIGVCVLAAAKAYIFRTFFKIMFLVMFFGAAHGLIFIPVFLTFF-----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q0EEE2-1", "uniprot_id": "PTHD3_MOUSE", "id": "Q0EEE2-1", "name": "Patched domain-containing protein 3", "aln": "--MISSKVAPGEEE---QGESPSKVELGEAEEQREAPLEGQLEA----VPLDEAGPSWTTGPPLERLPPLGQEAPPP----------------------------------RRCHTNCLEAPLSRGFQRFGATVGANPWLFLLGPALLTASLGTGLIFLPK-EKENLEEQYTPIGSPAKAERRFVQGHFSTNDTYRFSASRTSSETNFASILVVSLANSLLEPEIFKEVSKLDQAVQALKVVQENGTQILYQEVCAKYKTLCVPPNPLLFSWQHNSSLNLSDLTFPIHNTPTQLIYLAGFFGGNVLG-QMTGKSQRLVESRAMRLLYYLKTEDPEDSERSQAWLTHFLDHFNDMKSSLTLEEIEVVYFSSLSRQLEFEATSKTVIPLFHLAYILIILFAVVSCSRLDCIRNKMCVAVFGVFSVAMSVVSGFGLMLHLGVPFVIIVANSPFLILGVGVDDMFIMISAWQKTSLSESIRERLSNSYSKVAVSITITTITNVLAFYTGITSSFRSVQYFCIYTGTTLLFCYFYSITCFGAVMALDGKREVAWSRWLEKPDQ------KYSSLKKSCCVPFGSLIDKHGEDNHPMNLFFRDYFGPFLTTSKAKFIVVLLYIFYIISSIYGCFQVQEGLDLRNLASDDSYITPYFNVEEDYFSDYGPRVMVIVTESVNYWDNDVRQKLDKCMTQFEENEYVDKNLTEFWLEAYMQYMNSSGNNPNDKNTFMNNIAGFLQFFPIFTYDINISSSNEITSSRGFIQIVDVSSSSNKKRMLLKLRSIAENCEVPLMVYNQAFIYFDQYAAIIENTVRNVMIASTAMFIVSLLLIPHPVCSLWVTFAIASVIVGVTGFMAFWNVNLDSISMINLVICIGFSFDFSAHISYAFVSSTEPSVNKKSIEALYLLGYPVLQSAISTIIGVCVLSAAKAYIFRTFFKIMFLVMFFGAAHGLIFIPVFLTFF-----------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3KNS1-1", "uniprot_id": "PTHD3_HUMAN", "id": "Q3KNS1-1", "name": "Patched domain-containing protein 3", "aln": "MPWVEPKPRPGPEQKPKLTKPDSATGPQWYQESQESESEGKQPPPGPLAPPKSPEPSGPLASEQDAPLPEGDDAPPRPSMLDDAPRLPLELDDAPLPEEETPEPTAICRHRHRCHTDCLEGLLSRTFQWLGWQVGAHPWIFLLAPLMLTAALGTGFLYLPKDEEEDLEEHYTPVGSPAKAERRFVQGHFTTNDSYRFSASRRSTEANFVSLLVVSYSDSLLDPATFAEVSKLDGAVQDLRVAREKGSQIQYQQVCARYRALCVPPNPILYAWQVNKTLNLSSISFPAYNHGRHPLYLTGFFGGYILG-GSLGMGQLLLRAKAMRLLYYLKTEDPEYDVQSKQWLTHLLDQFTNIKNILALKKIEVVHFTSLSRQLEFEATSVTVIPVFHLAYILIILFAVTSCFRFDCIRNKMCVAAFGVISAFLAVVSGFGLLLHIGVPFVIIVANSPFLILGVGVDDMFIMISAWHKTNLADDIRERMSNVYSKAAVSITITTITNILALYTGIMSSFRSVQCFCIYTGMTLLFCYFYNITCFGAFMALDGKREVVCLCWLKKADP------KWPSFKKFCCFPFGSVPDEHGTDIHPISLFFRDYFGPFLTRSESKYFVVFIYVLYIISSIYGCFHVQEGLDLRNLASDDSYITPYFNVEENYFSDYGPRVMVIVTKKVDYWDKDVRQKLENCTKIFEKNVYVDKNLTEFWLDAYVQYLKGNSQDPNEKNTFMNNIPDFLSNFPNFQHDINISSSNEIISSRGFIQTTDVSSSAKKKILLFQLRRIAEDCQIPLMVYNQAFIYFDQYAAILEDTVRNVLVASAAMFIVSLLLIPYPLCSLWVTFAIGSVIVGVTGFMAFWKVNLDSISMINLVICIGFSFDFSVHISYAFVSSSQPSVNQKSVEALYLLGYPVLQSAISTIIGVCVLAAAKAYIFRTFFKIMFLVMIFGAAHGLIFIPVFLTFFGRFI-------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RPB3-1", "uniprot_id": "A0A8M1RPB3_DANRE", "id": "A0A8M1RPB3-1", "name": "Patched domain-containing protein 3", "aln": "-------------------------------------MNGALCS--------VMNLCVFLILSHHSVLMEQNEKKPQ-------------------------------------RKYCVEKPISICFQKFGRFVGTYPWWFFISPLLISAVLGTGFCLLEDREANDIEDQFTPVNGPAKQERRFVQQNFPQNDS-LFSNQRLYTDGVYASFIAVTKSSNILTDAAFREIVILDRKVKELNVSTG-HEVLTFEGLCARRYKKCIPNKILDIHKYYGENLEATELSFPFFRFGFSYIFLGYSVGGVNLN------SSIIKSAKSVRLFYFLKEDN---RTRTDLWLNEFLKVFP---SNLSLNSIKVTHSTSLSRQVEFEANTKDVIPLFSITYVIAIAFSILSCLRFDCVRNKVWVATFGVFSAGLAVLSSFGMMLHIGVPFVMTVANSPFLILGIGVDDMFILISCWQQTNVHDRVETRLSNTYKEAAISITITTLTDVLAFYIGLMTPFRSVRSFCLYTSTSILFCYIYSITFFGAFLVLNGRRENSNKHWLTCKEVPEECAVGQSKWYELCCIGGAYDRHTGSEEVQPMNHFFKKYYGPFLTKSWTKVFVIVFYCIYLIVSIYGCFQIQEGIDLRNLAADDSYVVKYYDNEKAYFSEYGPNIMVVIRQEFPYWDEKYMSDLETCIEDFKNLSFIEKDIFTSWIKSYKYYGYHTKLNLSAEDVFKENLGTFLRFYSDFKQDVNFTN-NSIHASRFFIQTVNISTALDEMNMLNKLRDTAQKCPVPLLVYHPAFIYHDQYAVIVTNTIQNIAVTTAVMLLISLLLIPNPLCSLWVTFSIASVIVGVTGFMALWDVNLDTISMIILVVCIGFSVDFSAHISYAFVSNKKPSANEKAVEALFNLGYPILQGAVSTILGVVVLSASKNYIFRTFFKIMFLVIFFGLFHGLTFIPVFLTFFDMCNGTPAENKSGPEEQAMKKSYTNNIAKDGDVKEREIYDNHTFQSDNHQTCPSQPCSDIWMIAGNNHSVQDNHVCLASTVPMFRVDGQTYEVHMYEPSDDVMLKVNCQSKQRVEGQNCVSGNSNHIQDSGLPTPNCSELTIL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . . . :: * :. *:* :* * :* **: ** *::.* :::* ****: * . * :::*:::**:..*** ****** :*. **: ** .* :: :.*::.*: ..:* * *: ** *: *.* : : :**: *:* : : ...*: :.::** . :.* .** *. . : ::::**:*:** :: ::. **..:*. * . *:*:.*:*.: :*****:****.: ***:* ::*:: * *:: ** *:**:***: **.***:*. ::*:*.**::**:*****: **********:*******:**.*::*.: : : *:** *.:.*:******:*::**:* *: :.****: **:**. ::****:*.** ***.:.*:*:** ** : .. : **. . . . : :*:. **:.*:***** * :* :*:.:* :*:* ******::***:******:****:. *:: *: ***:***.:**:: : . ***:. ..*:.* *:: :::*:: *:.:* * . : . ::.* :*: ** :. * *:*.:. *.* :** *** ::*:: .: :* :** *:.* :**:**: ****.****.*: :*::*: ::::.*:::****** *:*******:*.***********:*.****:**** **:*****.***.********..:**.*:*::***: ****:**.*:***:** **:*:* *************::** *** ********* ", "identical_positions": 369, "similar_positions": 272, "identity": "33.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111221-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C437-1", "uniprot_id": "PEX5R_MOUSE", "id": "Q8C437-1", "name": "PEX5-related protein", "aln": "MYQGHMQ-----------------------------------------------------------LVNEQQESRPLLSPSIDDFLCE-TKSEAIAKPVTSNTAVLTTGLDLLDLSEPVSQPQTKAKKSEPSS------KSSSLKKKADGSDLISADAEQRAQALRGPETSSLDLDIQTQLEKWDDVKFHGDRTSKG--HLMAERKSCSSRTG----SKELLWSAEHRSQPELSTGKSALNSESASELELVAPAQARLTKEH---RWGSALLSRNHSLEEEFER-AKAAVESDTEFWDKMQAEWEEMARRN----WISENQ-EAQNQVTVSASEKGYYFHTENPFKDWPGAFEEGLKRLKEGD-LPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKYKYLVKNKK---GSPGLTRRMS----KSPVDSSVLEGVKELYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISG----------NIWAALRIALSLMDQPELFQAANL-GDLDVLLRAFNLDP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q925N3-1", "uniprot_id": "PEX5R_RAT", "id": "Q925N3-1", "name": "PEX5-related protein", "aln": "MYQGHMQG------------------------KGSRAADKAVAMVMKEIPREESAEEKPLLTMTSQLVNEQQESRPLLSPSIDDFLCE-TKSEAIAKPVTSNTAVLTTGLDLLDLSEPVSQTQTKAKKSESSS------KSSSLKKKADGSDLISADAEQRAQALRGPETSSLDLDIQTQLEKWDDVKFHGDRTSKG--HLMAERKSCSSRAG----SKELLWSSEHRSQPELSTGKSALNSESASELELVAPAQARLTKEH---RWGSALLSRNHSLEEEFER-AKAAVESDTEFWDKMQAEWEEMARRN----WISENQ-EAQNQVTVSASEKGYYFHTENPFKDWPGAFEEGLKRLKEGD-LPVTILFMEAAILQDPGNAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTSHQQDACEALKNWIKQNPKYKYLVKNKK---GSPGLTRRMS----KSPVDSSVLEGVKDLYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISG----------NIWAALRIALSLMDQPELFQAANL-GDLDVLLRAFNLDP----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8IYB4-1", "uniprot_id": "PEX5R_HUMAN", "id": "Q8IYB4-1", "name": "PEX5-related protein", "aln": "MYQGHMQKSKEQGYGKLSSDEDLEIIVDQKQGKGSRAADKAVAMVMKEIPREESAEEKPLLTMTSQLVNEQQESRPLLSPSIDDFLCE-TKSEAIARPVTSNTAVLTTGLDLLDLSEPVSQTQTKAKKSEPSS------KTSSLKKKADGSDLISTDAEQRGQPLRVPETSSLDLDIQTQLEKWDDVKFHGDRNTKG--HPMAERKSSSSRTG----SKELLWSSEHRSQPELSGGKSALNSESASELELVAPTQARLTKEH---RWGSALLSRNHSLEEEFER-AKAAVESDTEFWDKMQAEWEEMARRN----WISENQ-EAQNQVTISASEKGYYFHTENPFKDWPGAFEEGLKRLKEGD-LPVTILFMEAAILQDPGDAEAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTGHQQDACDALKNWIKQNPKYKYLVKSKK---GSPGLTRRMS----KSPVDSSVLEGVKELYLEAAHQNGDMIDPDLQTGLGVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPGFIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISG----------NIWAALRIALSLMDQPELFQAANL-GDLDVLLRAFNLDP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQ86-1", "uniprot_id": "A0A8M3AQ86_DANRE", "id": "A0A8M3AQ86-1", "name": "PEX5-related protein", "aln": "MYQGHSQE----------------------------KDSRAVAIVLKELPSKGSSDGKPLLTVTNKLCSEQQESRPLLSPSIDDFQSE-SKTDGATRAVTSNTAVLSTTLDLVDLSEPCERRWSWDRRSPRGSRKNGFSKSSLRKKKTEETELIQVETEPSSPSRSNPERASLDSVSSSPLDKWEEVSLHPDSALNGGRKWRYERKRCTSNHS----SSELLWSADFKT--DFSNRHSALELSISTESD---PGPAPQRQKP---QLGGSLLGRQHSLEEEFVR-AKAAVESDTEFWDKMQAEWEELARRN----WLEDADSEGLVPLNFSPTEKGYFFHANNPYKDYSNAFEQGQQKCRDGD-LNSAVLLLEAAILQDPQDSEAWQVLGTTQAENENEQAAIVCLQRCLELHPNNLKALMALAVSLTNTGQQPEACEALHRWIRYNPRYSHLLQDRSPLDGSPLPRRRGSSISRISTLGCSQLVEVLELYQEAVQLNTEEVDPDLQTGLGVLFNLSSEFDKAVIAFNAALSIRPEDYLLWNRLGATLANGDRSEEAVEAYTRALELQPGFIRSRYNLGISCINLGAHREAVSNFLTALHQQRKSRS-----HKVMSS----------NIWAALRIALSLMGQPELFQAASV-GDLDLLMKAFNMDM----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O46085-1", "uniprot_id": "O46085_DROME", "id": "O46085-1", "name": "Peroxisomal targeting signal 1 receptor", "aln": "MVQSGIWR------------------------------SKPILWRIRFCAAIYFIIIRALCNTVTKPIASITADKQLRSISTSNTMSFRPLVEGDCGGVNPLMQLGGQFTRDVAHKDEGYVQRHFERAARPEDQ----LINEFLGQVTAPPQSFQMDTLLQEMRDINIHGNPQQQMHSQQAEQWGQDFARGLAPALPNKMIHMQAQQQDLQHAQEFFDEPLISSQNFRSLPPLRQPLMPIAAGQQQDPFFDSAMETIITDHLPQAPQGESLDDWISDYQRSTEQKEQTAANFNEKFWERLQDEWQKLADENEH-PWLSEYN-------DNMDAYKEYEFAEGNPMSDVENPFEKGKEYLSKGD-IPSAVLCFEVAAKKQPERAEVWQLLGTSQTENEMDPQAIAALKRAYDLQPDNQQVLMALAACYTNEGLQNNAVRMLCNWLTVHPKYQHLVAAHPELQAEGTSLAS-------SLIGPSKLRDLQQIYLEAVRQHPSEVDAEVQDALGVLYNLSGEFDKAVDCYQSALQVDPQNAKTWNRLGASLANGSRSVEAVEAYQQALQLQPGFIRVRYNVGVCCMNLKAYKEAVEHLLTALTMQAHTNAARELPNAAMAATFRGQNQMSESIWSTLKMVISLMGRSDLQSYVSD-RNLAALNEAFKD------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P35056-1", "uniprot_id": "PEX5_YEAST", "id": "P35056-1", "name": "Peroxisomal targeting signal receptor", "aln": "MDVGSCSVG-----------------------------NNPLAQLHKHTQQNKSLQFNQKNNGRLNESPLQGTNKPGISEAFISNVNAISQENMANMQRFINGEPLIDDKRRMEIGPSSGRLPPFSNVHSLQTS----ANPTQIKGVNDISHWSQEFQGSNSIQNRNADTGNSEKAWQRGSTTASSRFQYPNTMMNNYAYASMNSLSGSRLQSPAFMNQQQSGRSKEGVNEQEQQPWTDQFEKLEKEVSENLDINDEIEKEE---NVSEVEQNKPETVEKEEGVYGDQYQSDFQEVWDSIHKDAEEVLPSELVNDDLNLGEDYLKYLGGRVNGNIEYAFQSNNEYFNNPNAYKIGCLLMENGAKLSEAALAFEAAVKEKPDHVDAWLRLGLVQTQNEKELNGISALEECLKLDPKNLEAMKTLAISYINEGYDMSAFTMLDKWAET--KYPEIWSRIK---QQDDKFQKEK-----GFTHIDMNAHITKQFLQLAN-NLSTIDPEIQLCLGLLFYTKDDFDKTIDCFESALRVNPNDELMWNRLGASLANSNRSEEAIQAYHRALQLKPSFVRARYNLAVSSMNIGCFKEAAGYLLSVLSMHEVNTNNKKGDVGSLLNTYN------DTVIETLKRVFIAMNRDDLLQEVKPGMDLKRFKGEFSF------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q04364-1", "uniprot_id": "PEX9_YEAST", "id": "Q04364-1", "name": "Peroxisomal targeting signal receptor 9", "aln": "-------------------------------------------------------MNEVTCSITGDNPIHKINNGLGLKWNNLGKFSDFQTNDSAARDARTIDYIFTNCQTGSSIGKIDFRAALPADKSQHSG-------VSEKEFSRLENQWSKEFSCFPKNKNADVTKPSRNKHEKRSANLHNRYFAQYYSTAYQQNRIYPCRISYNEHSS-------------------VSNGWEFQFKSIENQLLNELKIENNVEEKT----------------------VGYEYVAEYEETIDFMH---------------------------MLSSVPQTYQFLKSNIYITERDPYKIGCVLMDNGSNLNEVVMAFEAAISQDPSHINAWLKLGIVNFENESESNGELALRNCLNLDPNNTIALENLAIHHINQQNESESLKLFHKWILS--KFSKVFQPSAG--ENKDSINKIP--------KKAHLAHILESLLNMGIEKKDQYD--IYSVLSILYYSDQKIKQSQKCLEFLLLEKPNNGTIWNRYGAILANTKSYHSAINAYNKCKQLRPNFTRVRYNLAIAYMNKGDYVKASKMLIEVILLRSKGYEHNKAKMQN-------------KFMQNLKNALIASKNFDSLDLINGSHNTESLISTLKAIYNKMD", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : . . : . . : .. : : :: * * * ..:: * .* : . : :*.* :.* :.* ** : :** : . .*... .*.*.* .: ** * : .: : .* :: : . : . : : . * : *.:*: . .:.:: . : * *:: *** ** *** . .*::** :. :::*.* * ***:.:. :* . :* :: .: : .. *: .: . : . . : : :. ", "identical_positions": 46, "similar_positions": 106, "identity": "6.86%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111221-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M6T3-1", "uniprot_id": "F1M6T3_RAT", "id": "F1M6T3-1", "name": "", "aln": "MYSVEDLLISHGYKPAR---------DAPVPREDKSERCRSRRTG-------PQAGQGLLNGYK-DGPTAHAHSRTALGTGHVSNSEKHSSKPRGHQEYQSSSS--RTPEAGFLSQP-----SLAWSSQPQSGRDHIYWSRGQQEGSGSLCPRDQEEVEVRRMAQAHSLPIHVRESPWEVARRTEHVMKNALWEAELRMPTPAKWQDMTLESWKQPRK-----LG----RQASDGDGQKRSQERFEDLYQFVHGEHMLTSQNRKKSQSLPRALSPKSLNFTEIPVP----LHDGHITGVPKVPPYPPSCPPPLEPTRNLEKTSSSGPFPRPKFGKPLKTPCHGSQPQPRGEGGFQD--HQHRDPRGCHPTRSKDPGHELGMLDTGLEPPVYVPPPSYRSPPQHIP-NPYLEDPIPRHVSSSQSQQQQLPEKPEADCLLPSGSLAARDLYNAMPGSPPPGPPPHPYPIATHGDSIQYIPFDDPRIRHIKLAQPPEFYEEARLEDTSYNSGFIATQEPALGKRQYNDALSAPRGPILPPVNERGSAFAHSSPQWLQGQLPMASEPGGFPGQTEHHGMRGLTADVRDS---KVESHASSPQPQSEGTCRTHTKLRKFETGIQS--RKSSKK-SNATIFCLVSVPVKSESLVPDTDTNNNDLKLGADKNHGLYQGPALEEQSLLSMSSTDLELQALMGSMAWRRTSPRQVLGESE-DGQTDDPRTLHLIKPRELRASGSWPGHQYRDQQTQTSFPEDSKSSQLLPATKPGEASNAALTPTCPDDTASEVHLHAALASSDPSQKPSVPHLRGQMSLSPSRNSAFSRTSSTINQTSMPKGASGQ------LPSANPVPKPEVVKGESTVGQCNSTQLFGQFLLKPVSRRPWDLISQLESFNKELQE---------------EEESHGVSSGGD--SEDSEAE-QPEDCADSSAKTRGHQET----RREQRPAELALGEAGPPGGR-LGESQSRSKEPKPGHPCARSQALGP----SQEEDSRGVPVQWGHGNLSAEQKSQEALNGMCERDISPRPVSRIAP--VDTQAASLFCLAEPRGSQELTKVNDALGSVELGRETPIRVDNGGDTEVLPCVLPPLADRCRGLSTPNFP----------------------------------------------SLELTLGQEQR----AYKSE-CQGLDNTVEVLPSESLQERAERILGIEVAVESLLPGARRTEQSQLPKPGTSACSPRSSREDSQP------------------------------SSASPEDPTVATDAFYGRRKCGWTESPLFVGER----------APQAAVCSDVDGFPTSQATSPEP----------EKK-KEAKPPFKSTLFHFMEKSTNVVGPEKRLRNSSNVIESSQGKLVSLPKRADSARLVRMREVNSLSQMRCLSSKSADSMEEPDPLKVIKS-SAWPSEGLTSPSGKDQAWQAEYLPSVSQN-----ENGHPEVIREKMSDQD-LWCADSYDPSRVERV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5DTX6-1", "uniprot_id": "JCAD_MOUSE", "id": "Q5DTX6-1", "name": "Junctional cadherin 5-associated protein", "aln": "MYSVEDLLISHGYKPAR---------DAAAPCEDKSERCRSTRTG-------PRAGQGLLNGYK-DGATAHTHSRTSLGTGHVSNSENRISRPRGHREHQSTS---RTPEARFLNQP-----SLAWSSQPQSGRDDIYWSRGRQEGSGSLCPRDWKELESRGMAQAYSLPVHVRENLWEVAGRTEHVMKNAIWEEELRM------QDMSLESWKKPRE-----LG----RQASDGDGRKRPQEKFEGLYPFVHGEH--TSQNRKKSQSLPRALSPKSLNFTEIPVP----LHDGHITGVPKVPPYPPSFPSPSEPMRNLEKASSSGPFPRPKFGKPLKTPCYSSHSQPRGEGGFQD--HQHRDPRGSYPTRSKDPSHELGMLDPGLEPPVYVPPPSYRSPPQHIP-NPYLEDPVPRHVSSNQSQQQ-VPEKPETSCPLPSGSLAARDLYDAMPGSPPQGLPPQPYPIATHGGSIQYIPFDDPRIRHIKLAQPPEFYEEAKLDDTSYNPGLLTTQEPAIGKRQYDDAPSVPRGPTPSPVNEQSSAFVHSSPRWLQGQLPLGIGPGGFHGQTEHHVMGGLTTNVTDI---KAEGHASSPQPQSEGTCKTYTKLRKFETGVQS--KKSSKKKSNATIFCLVSIPVKSESLVLATDTNNNDFKLVADKTRGLCQGSALQEQSLLSMSSTDLELQALMGSMAWRRTSPRQGLRESE-DGQIDDPRILHLIKPKELQASSPWPGHQYRDQQTQTSFHEDSKSSQLLPATKPGEASNVAPTPTCPDTTASEVCLHTALAFSDQNQKPSVPHLQGQTSLSPSRNSAFSRTSSAINQASMSKGTSDQ------LPGANPVPKPEVVKGESTTGQCNSTQLFGQFLLKPVSRRPWDLISQLESFNKELQE---------------EEESHGGSG-----SEDSEAE-QPEDCADSRTKSWALQGT----RTAQQPAGLALENVASPDRR-LNDSQSWNEEPKPGHSSVHPQSLGP----SQEEGSRGVPVQWADGSLTAEQKSQEDLNGMCERDFSPRPVSRIAP--IDTKAAPLYCLSEPRGSQELTKFGDAVGSVQLGRETPTQVGNGGDTEVLPCVLLPLADKYRGHSTPDFR----------------------------------------------SLELTLGQEQN----AYKLE-CLDLENTVEVLPSESLQERAERILGIEVAVESLLPSARRTEQSQLPEPDASACNPSSSREDSSH------------------------------SLALPVGPKVATDAFYGRRKCGWTESPLFVGER----------APQASICSDVDGFPTSQATSPEP----------GKKDEEAKAPFKSTLFHFMEKSTNVVGPEKRLRNPSKVVENLQEKLVSPPKKADSVHLIRMREVNSLSQMRCLSSKSADSVEEPDPLKVIKS-SAWLSEGLTSLGGKDEAWQAGHLPSVSQN-----ENGHPEVPRDKMSDQD-LWCADSYDPSRVERV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P266-1", "uniprot_id": "JCAD_HUMAN", "id": "Q9P266-1", "name": "Junctional cadherin 5-associated protein", "aln": "MYSVEDLLISHGYKLSR---------DPPASREDNPKGRQAARTG-------TRAGQGLQNGHE-DGPAALAHRKTSAGKGHVSDSESRRSTPRGHGEPQSTSAS-RTSEAGFCNQP-----PSAWSSHPPTGNDQAYRRRGRQE-ARSQKPREHENLEARGMAQAHSLPVHVREGPWEVGGRSEHVMKKPVWEEELRMSGPAKWQNVSLESWNQPRK-----LG----RQMSDGDGER----LFQDLYPFIQGEHVLNSQNKGKSRSLPRVLSPESLSCTEIPIP----LNERHS---PKMPPYPPTCAPNLDSTRNSEKSGCSAPFPRPKFGRPLKPPSYSSHQQSRGGADSSD--SQDSQQMDAYVPR-----HELCLSDPGLEPPVYVPPPSYRSPPQNIP-NPYLEDTVPINVCGGHSQQQSPTEKAGASGQPPSGPPGTGNEYGVSP-RLPQGLPAHPRPVTAYDGFVQYIPFDDPRLRHFKLAQPQGFCEDIKLDDKSYNSSPVTAQEPAHGGMQPDGAIWNPQSLIPPSGDERGLVLADSSPRWLWGQPPGDGENSGLPNQRDRCVARGQWPDVRGSQHGHTGRQVSSPYSQGESTCETQTKLKKFQTGTRT--KKSSKKKMNETIFCLVSIPVKSESHLPDRDMDNNDLKPSADQKNGSDKSPALQEQSLLSMSSTDLELQALTGSMGGRTEFQKQDLGEPEEDRQTNDLSFIHLTKHRELKHSGSWPGHRYRDQQTQTSFSEEPQSSQLLPGAKLGGPSRAALSPKCSDPAASEAQTHTAFPTGDHKQRPSARNLKGHRSLSPSSNSAFSRTSLSVDQAPTPKAGRSQPCVDVHGLGAHPGPKREVVKGE-PTGPCNSKQLFGQFLLKPVSRRPWDLISQLESFNKELQE---------------EEESSSSSSSSSSSSEESEAEPQQENRAHCRQEDVGFRGNSPEMRVEPQPRMWVPESPVCRSGRGESKSESWSEELQPGHPRAWPPSPGR----FRVEEGGGAPFCSADGSTSAEKRHLEVSNGMDELAGSPFPVTRMSSRSSDAKPLPASYPAEPREPQESPKITSAFSSVKPSEAVPRKFDSGGERGAG--LPLSLSNKNRGLSAPDLR----------------------------------------------SVGLTPGQEQG----ASELEGSLGEASTIEIPPGESLQARAARILGIEVAVESLLPGIRRAGQNQPAEPDASACTPESPQEELLS------------------------------RPAPADVPRVSTDAFYGRRKCGWTKSPLFVGDRDSARR-----APQAFEHSDVDGVVTSTDPVPEPEPSPLESKFFEQKDVETKPPFRSTLFHFVERTPSVAGSEKRLRSPSKVIESLQEKLASPPRRADPDRLMRMKEVSSVSRMRVLSFRNADSQEDAEELKATTRGQAGLPGGLVSPGSGDRAQRLGHSLSVSKDSISREEKEHPAAQKEKSMDQD-FWCPDSYDPSRVERV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q0Q1-1", "uniprot_id": "A0A8M9Q0Q1_DANRE", "id": "A0A8M9Q0Q1-1", "name": "", "aln": "MYSVEDLLISHGYKVPQRNSNNVPVSHSSSPQPATYEKCLPTRSDSRCEIAEKRKGHSGVNGYEGDHVYSGGGIRQAPARGFPGDAENRVRKQRTQDVDNGNLGDGRLPEDSLTTDSGFFEAHRGIHSQPRSEQDVSYWRRRGQDFSVLLDYADFRDPRGSGGGGVANKPEGMQRRPESALSTEEHNRERQRRAESARARE----REMALHQWRIAAERKYQSLGTEEWRPMTSMSRQPSENEVAHDQRRPRTAEGAVPPRTKNKSQSLPRMQS-ESLQYFSIPTAGQDSYGGFKLNGHHIRDPHGRHIDGENRQRWTDRSGAQSAPLSKPRFSRPLRPPSYEAHQQMRGSAEMLTGELAPRARDRTPLPFSRQEYFVQELGGSGAEPPGYIPPPSYRRQPVIKGGHRTYPISMANHQYRGDPYMQSSAMTEVQEWFIRQTGMAWPDHYRDGRRSMPCRRQAYPGYSEERMGNVQYIPFDDPRVRHISGAG---IDGNSLTDADKIRNIRNEIPVNLIPEKSNDSALPFTEKPFDRTDPNKSNISNSINEDSMHKESLKETECSNTVPDQNCNRHPVTHGNIVAL-------QMTTQQNSSLGLIETVTQVKKFEAKTVAENKKNSKKKLKETMFCLVSVPISMQANRSVSDPNNNQKVISSQDNTGVQQ----DNQNMLKASSKETHIQSNS----------SPSIRNPPLKKEITDTRSLDPSQDSEVFYAGSWPGDQYRNQETQTGSPEVSRN--------THSSANDHPSPFTITNNEGETNCSANYGYP----------MIGQKDLNHSSNSAFSRTVNGISVRSPHFPRSVS-------LPSSPDHQPLLRKSK---QSSESQELFGQFLLKPVNRRKWDAIGELESFNKEIQDHTGKFPNAEQNTKELDEALNSVLELSDASNNSKQETPPPHTNKEIDQQPHVVQVTDMQLKSNNLNITSHSGKGGHPEYKGLKSSLSKTKVNFDTHTQQIPVSKTDNYVNFDILQRGDNDPVMHRQDIPVPKECLLKDVGLTVYTAIPDTVTSGSPTCLSPESPMLTSPSDNSEMCETLQITSSDSSGDLSRHSPEFSEGTQSLNNNNAFNSKKLKKEAGRGSTDVIKSERSSRIHVIKSLHCRFKANFEDDDDEHFYSDYLSWSNEKTLADEHLETLLSQEKANNMQTEDLSNLYQVQCAKGIPENESIEQRAARILGISVPVEALVVDQVDGKPLERDFKNTDATVLETQTKEMSLNDETQNVCREFEEVPNRSMESQGHALEVELGEDPESTEDLSSAEKHSLRVSTMLELPEFPPSNLCLSLPLTEDEELTLSVSGGDRKETVNAEITEAPQDQLQACCLSSLSPSSTNDKASLEYNVYAKEESCQPLVRTVNRITLAKETDQEEEEGEALQESAQEEETLVEEKQYSENAVVMTSYMQEENEETAQEEVSAEVLLLARSRQSPKTMARPIPHPRSGMVAKREITLPQGFNLDNTVSAIEDDDKLFISDAYDPSRVERV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************** .: ... . . : . *:. : *:. **:: * : : : . *. .::*.: * : :.. * .* : .:. . *:* : .* * * *: : : .: . . . . * ::. .. ** :. . * ::::*..*. . : ** * :. . . .. .* .:.: **:**** * :**. .** . : *: . .. . *.*:.:*:*.:**:.*.: :: * ** . . . : ..* *** *:****** * : .:. : ... * . . . . . : * * . * . :*********:**:. * : : : . . . :.* .. . ::. . : : .. : : :: : :: .. . .* *:::**:: : :*.*** : *:*****:*:. :: * :**: ::.. * : ::*.:*. **.: .:*: : :. . : * :. : *: :..***.:**:*:***. * .:. .:. :* .*. : : *: .*. * ******* :. . . : * : : *.: .:* :**********.** ** *.:*******:*: :* . .:..: . . : : . : . : .* * .: *. . : . . .. :. *: * .*: :. ..:. :: * :. .: .* . .. * . . . .: * .:.:. : .**: : . . : : .**:: ** *****.*.**:*: . : .:.* : :: ::: :. * . : * * .. : *. * * .*. . .:. * ::. : . : :. : . *. * : . . : .. . : * .. *. : :. :: : . . . * .. *:: : : . *:* :: .*:*********", "identical_positions": 218, "similar_positions": 376, "identity": "14.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111221-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96G91-1", "uniprot_id": "P2Y11_HUMAN", "id": "Q96G91-1", "name": "P2Y purinoceptor 11", "aln": "MAANVSGAKSCPANFLAAADDKLSGFQGDFLWPILVVEFLVAVASNGLALYRFSIRKQRPWHPAVVFSVQLAVSDLLCALTLPPLAAYLYPPKHWRYGEAACRLERFLFTCNLLGSVIFITCISLNRYLGIVHPFFARSHLRPKHAWAVSAAGWVLAALLAMPTLSFSHLKRPQQGAGNCSVARPEACIKCLGTADHGLAAYRAYSLVLAGLGCGLPLLLTLAAYGALGRAVLRSPGMTVAEKLRVAALVASGVALYASSYVPYHIMRVLNVDARRRWSTRCPSFADIAQATAALELGPYVGYQVMRGLMPLAFCVHPLLYMAAVPSLGCCCRHCPGYRDSWNPEDAKSTGQALPLNATAAPKPSEPQSRELSQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P2Q4-1", "uniprot_id": "A0A8M1P2Q4_DANRE", "id": "A0A8M1P2Q4-1", "name": "", "aln": "----MKNDSLCNE----------SQFQIDLLPPMYGIEMTVALLGNIFALWLLGTRERKDWHTGVVFSCNLAISDVLYILTLPLLIIYYGKKKNWTFGDAVCKIERFLFTSNLYVSIFFIMCISVNRYIAIVYPFFTRSYVRPVHAKIASVLVWFIVIITSSPVFSFAGTEVVESDR----VHNRTLCVSCK--DKSRAKSHLKYTLFLMVVGCMIPFLVTFASYLGVIWTVLKNKNITTLEKRKVALMVALVCILYATSFVPYHFLQTYHVYLK---------------SENLKECWLYNSYQVSKGLATLNMCLHPLLYMAVFDSIRTVC--CGRSSDD---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.. . * * ** *:* *: :*: **: .* :**: :. *::: **..**** :**:**:* **** * * *:* :*:*.*::******.** *::** ***:***:.**:***:**::** ** .*. *.:. : : *.:**: : :.. * . *:.* . :: *:*.* :** :*:*:*:*:* .: :**:. .:*. ** :** :** ***:*:****:::. :* : : * * .*** :** .* :*:*******.. *: * * *. ", "identical_positions": 120, "similar_positions": 94, "identity": "32.09%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111223-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5NBY9-1", "uniprot_id": "PATZ1_MOUSE", "id": "Q5NBY9-1", "name": "POZ (BTB) and AT hook-containing zinc finger 1", "aln": "MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDGGAADGGPADVGGAAAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPAR-ADIMLFRPPGTSDLGFPLDMTNGAAMAANSNGIAGSMQPEEEAARATGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFPNVASSAPPLTSKRGRGRPRKANLLDSMFG--SPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTS------LQLGYIDLP--PPRLGENGLPISEDPDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEGPSNFCSICNRGFSSASYLKVHVKTHHG---VPLPQVSRHQEPILN-----GGAAFHCAR---------------TYGNKEG---------------------------------------------------------QKCSHQDLIESSDSYGDLSDASDLKTPEKQS----------ANGSFSCDVAVP---KNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPMGPEGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HBE1-1", "uniprot_id": "PATZ1_HUMAN", "id": "Q9HBE1-1", "name": "POZ-, AT hook-, and zinc finger-containing protein 1", "aln": "MERVNDASCGPSGCYTYQVSRHSTEMLHNLNQQRKNGGRFCDVLLRVGDESFPAHRAVLAACSEYFESVFSAQLGDGGAADGGPADVGGATAAPGGGAGGSRELEMHTISSKVFGDILDFAYTSRIVVRLESFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPAR-ADIMLFRPPGTSDLGFPLDMTNGAALAANSNGIAGSMQPEEEAARAAGAAIAGQASLPVLPGVDRLPMVAGPLSPQLLTSPFPSVASSAPPLTGKRGRGRPRKANLLDSMFG--SPGGLREAGILPCGLCGKVFTDANRLRQHEAQHGVTS------LQLGYIDLP--PPRLGENGLPISEDPDGPRKRSRTRKQVACEICGKIFRDVYHLNRHKLSHSGEKPYSCPVCGLRFKRKDRMSYHVRSHDGSVGKPYICQSCGKGFSRPDHLNGHIKQVHTSERPHKCQTCNASFATRDRLRSHLACHEDKVPCQVCGKYLRAAYMADHLKKHSEGPSNFCSICNRGFSSASYLKVHVKTHHG---VPLPQVSRHQEPILN-----GGAAFHCAR---------------TYGNKEG---------------------------------------------------------QKCSHQDPIESSDSYGDLSDASDLKTPEKQS----------ANGSFSCDMAVP---KNKMESDGEKKYPCPECGSFFRSKSYLNKHIQKVHVRALGGPLGDLGPALGSPFSPQQNMSLLESFGFQIVQSAFASSLVDPEVDQQPMGPEGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TT90-1", "uniprot_id": "A0AB32TT90_DANRE", "id": "A0AB32TT90-1", "name": "", "aln": "MERTEQPWN---SSYTYQVSKHSAEMLHNLNGQRKDGGRFCDVILRVGEESFPAHKAVLAACSEYFESVFSCQTEDDGQG---------------------KELEMHTISPKVFRDILDFAYTSKIVVRLECFPELMTAAKFLLMRSVIEICQEVIKQSNVQILVPPSRGGEHSLFRAAEQLSYPLPVDMSNGSVSN-------GAVFTDNNDSDSADPSNISQPAAPGAPTADRL-----AVSPLEFSSGHLNIDG------FKRGKPRPKKEPIAQPVTYNNSTGQNEEGALFSCGICGKMFPDEVQLRNHEAQHGTFTGVMSSGIELVVVDGPTMISHPGQQRFQGNGLPTDTRKRERTRRHVACDLCGKVFRDVYHLNRHKLSHSGEKPYACPVCGLRFKRKDRMSYHVRSHDGSVGKPYVCQSCGKGFSRPDHLNGHIKQVHTTERPHKCQICNASFATRDRLRSHLACHEDKIPCQVCGKYLRAAYMTDHLKKHSEGPHNYCGICNKGFSTASYLKVHVKTHHSSSMLPSSAAHQFPEPRTNRPQTHNGAPYHSGRQCAVEDLCTSRRLLVTFPETEGSFRGLSGPVLPQPVPPGLQPELLMGKPGPTPYFWECRSSGAPGFPLHGPLPDGQENAGKCPHQDSDGSDAVFGDLSNGMDLKAEHKVEGEEMEVTSFIFNGQPDDAVTSPEGSKNIPTTDQEKKFACGECGQAFRTKSYLNKHHHRVHKKRAAAAS-SLG-DLASPFSPQQNMSLLESFGFQIVQSAFASSLVDSEIGSSGMGLGEK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.::. ..******:**:******* ***:*******:****:******:***************.* *.* . :********.*** *********:******.***********************************:* .: ***.. . :*:**:**:. *:: .::: : ::..: .*.: * * .*** .:** ::* . .: . ***: **:* : :.: *.* .*..::.**:***:*.* :**:******. : ::* :* * .: *:: : . * ..***.***::***::***:********************:*****************************:***********************:******* *********************:**************:********** *:*.***:***:************. :* . . :. ** * .**.:*..* *: :.** **.*** *. :****:. ***: .* . **. . :: * ** :* ***:.* ***. **:******* ::** : ... .** *.******************************.*:... ** *", "identical_positions": 407, "similar_positions": 144, "identity": "51.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-111229-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D3X9-1", "uniprot_id": "MFA3L_MOUSE", "id": "Q9D3X9-1", "name": "Microfibrillar-associated protein 3-like", "aln": "-----------MGLQKSHLTVCLPPSVPFLILVSTLATAKSVTNSTLNGTDVVLGSVPVIIARTDHIIVKEGSSALINCSAYGFPDLEFKWYNSVGKLLKEMDDEKEKGGGKWQMLDGGLLNITKVSFSDRGKYTCVASNIYGTINNTVTLRVIFTSGDMGVYYMVVCLVAFTIVMILNITRLCMMSSHLKKTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKTMEFARYIEELARSVPLPPLIMNCRTIMEEIMEVVGLEEQGQNFVRHTPEGQE------APDRDEVYTIPNSLKRSESPTADSDASSLHEQPQQIAIKVSVHPQSKRDHVDDQEGGHFEVKDEEETEPSEEHSPETAEPSTDITTTELTSEETSPVEAPERGLPPAHLETTEPAVTCDRNTCIIYESHV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75121-1", "uniprot_id": "MFA3L_HUMAN", "id": "O75121-1", "name": "Microfibrillar-associated protein 3-like", "aln": "-----------MDRLKSHLTVCFLPSVPFLILVSTLATAKSVTNSTLNGTNVVLGSVPVIIARTDHIIVKEGNSALINCSVYGIPDPQFKWYNSIGKLLKEEEDEKERGGGKWQMHDSGLLNITKVSFSDRGKYTCVASNIYGTVNNTVTLRVIFTSGDMGVYYMVVCLVAFTIVMVLNITRLCMMSSHLKKTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKTMEFARYIEELARSVPLPPLIMNCRTIMEEIMEVVGLEEQGQNFVRHTPEGQE------AADRDEVYTIPNSLKRSDSPAADSDASSLHEQPQQIAIKVSVHPQSKKEHADDQEGGQFEVKDVEETELSAEHSPETAEPSTDVTSTELTSEEPTPVEVPDKVLPPAYLEATEPAVTHDKNTCIIYESHV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F6P5-1", "uniprot_id": "E7F6P5_DANRE", "id": "E7F6P5-1", "name": "", "aln": "MTSHCYREPLKMKRVNGYVIIYLASVISFCAAGALNITAVDGEGGENRTEANGAGSIPVVVTKTSQIIAREGNCALIDCNVTGDPFPNVQWFNSHGHLLDTK-----KSDGKWWILDSGVLNITSITFADRGKYTCVASNSHGTANCTVTLRVVFTNGDMGVYYMVVCLVTFTIIMILNITRLCMMSSHLKKTEKAINEFFRTEGAEKLQKAFEIAKRIPIITSAKTLELAKVTQFKTMEFARYIEELARSIPLPPLIMNCRTFMEEILEVVGVEEMRHTFVRQAPESLDGHGAVAASNPADVFTILRERERSESPAADSDDASLHEQPQHIAIQVSVHPQLTS-------PGCCNIEAPPLSEIGSTSPPPLAQLPLVEESVEQENKEESVQEG-----------------GATKKTQVIYESHV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :.:: : : . :.* : ** . .. . **:**::::*.:**.:**..***:*.. * * :.:*:** *:**. :..*** : *.*:****.::*:*********** :** * ******:**.*************:***:*:**************************************************************************:***********:****:****:** :.***::**. : *.: :*:** .. :**:**:**** :*******:***:****** . * ::: :* . .* *: . :.* .:* : * ::* :******", "identical_positions": 216, "similar_positions": 89, "identity": "50.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120104-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43653-1", "uniprot_id": "PSCA_HUMAN", "id": "O43653-1", "name": "Prostate stem cell antigen", "aln": "-----MAGLALQPG-----TALLCYSCKAQVSNEDCLQVEN--CTQLGEQCWTAR--IRAVGLLTVISKGCSLNCVDDSQDYYVGKKNIT--CCDTDLCNASGAHALQPAAAILALLPALGLLLWGPGQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A3U9-1", "uniprot_id": "A0AB13A3U9_DANRE", "id": "A0AB13A3U9-1", "name": "", "aln": "MMNRILLGVITVIGFFTLAEALTCNSCKVGILG-KCLYSSQVACASSEINCYTASAVFNVTGFLSLSSSGCTSNCNNTVGTILGAGYSITKTCCITDLCNGASAVQLSTTAAFSTALLAS---IWSSYML", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : *: * ** * ***. : . .** .: *:. :*:** :...*:*:: *.**: ** : . .** ** *****.:.* *..:**: : * * :*.. *", "identical_positions": 38, "similar_positions": 35, "identity": "29.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120104-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PR68-1", "uniprot_id": "CE112_MOUSE", "id": "Q5PR68-1", "name": "Centrosomal protein of 112 kDa", "aln": "METG-----SEEEKWEKLDAEFDHFVVDMKPFVLKLPHRSERQRCALWIRKLCEPSGTGAGLMGRKNRNLYAKLLLHMLRRGILEGPFTHRPEPGTLKTLPSYMSIYFDEPNQAQPKDSSPEKLPDWVRGELQTGEQRLSDSWQCSSGEDNTLVLAASDAH-REQYTGKLRMRSHSVSPTYREDKQHITSKICEVHSKTSPISLDDSDIEVRLNSWNLGIENPRYLRQKPLPVSLMTPKGSLRKASSLHDDHFLSRMHEKELDMKTKMMEAKFSEEKLKLQQKHDAEVQKILERKNNELEELKILYKKKQTETEETIRKLEKKVQILIRDCQVIRETKENQITELKKICEQSTESLNNDWEKKLHNAVAEMEKDKFELQKHHTETIQELLEDTNVRLSKMEADYVVQMQSTNHMIKELEGRVQQLMGEAENSNLQRQKLTQEKLELERCYQITCNELQELKTRRNILHKEKEHLVNDYEQNVKLLKTKYDSDINLLRQEHALSTSKTSGVIEELEQNICQLKQQVQESELQRKQQVKDQENKFHMEKNHLKHTYEKKVHELQSELDKEKEDAQRKIHKFEEALKEKEEQLSRVTEVQRLQAQQADAALEEFKRQVEVNSEKVYGEMKEQMEKVEADLTRSKSLREKQSKEFLWQLEDAKQRYEQQIVELKLEHEQEKTHLLQQHSAEKDSLVRDHDREIENLEKQLRAANMEHENQIQESKKRDAQVIADMEAQVHKLREELISVNSQRKQQLIELGLLREEEKQRAAKDHETAVKKLKAESERVKMELKKTHAAETEMTLEKANSRLKQIEKEYTQKLAKSSQIIAELQTTISSLKEESSRQQLAAERRLQDVIQKFEDEKQQLIRDNDQAIKALQDELETRSHQVRSAEKKLHHKELEAQEQIMYIRQEYETKFKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEELTTYQSRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8N8E3-1", "uniprot_id": "CE112_HUMAN", "id": "Q8N8E3-1", "name": "Centrosomal protein of 112 kDa", "aln": "MEVG-----SEEEKWEKLDAEFDHFVVDMKPFVLKLPHRTERQRCALWIRKLCEPSGTGAGIMGRKNRNLYAKLLLHMLKRGALEGPFTHRPEPGTLKILPSYMSIYFDEPNPARAKGSSPEGLPAWVLGELETSEHKLNESWKLSSGEDNTLVQSPTDVYSREQYTGKLRVRSHSLSPTHREDGQNITPKICEVYSKKSPVSLDDSDIEARLNSWNLGIENPRYLRQKPIPVSLMTPKFSLRKSSSFHDDHFLSRIREKELDMKTKMMEAKFHEEKLKLQQKHDADVQKILERKNNEIEELKTLYRSKQHETEETIRKLEKKVQTLIRDCQVIRETKEDQIAELKKICEQSTESLNNDWEKKLHNAVAEMEQEKFDLQKQHTENIQELLEDTNVRLNKMESEYMAQTQSTNHMIKELEARVQQLTGEAENSNLQRQKLIQEKAELERCYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQTKYDADINLLKQEHALSASKASSMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHLKHIYEKKAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVELNSEKVYAEMKEQMEKVEADLTRSKSLREKQSKEFLWQLEDIRQRYEQQIVELKLEHEQEKTHLLQQHNAEKDSLVRDHEREIENLEKQLRAANMEHENQIQEFKKRDAQVIADMEAQVHKLREELINVNSQRKQQLVELGLLREEEKQRATREHEIVVNKLKAESEKMKIELKKTHAAETEMTLEKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEELTTYQGRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EZM2-1", "uniprot_id": "E7EZM2_DANRE", "id": "E7EZM2-1", "name": "", "aln": "MSSANWSNMSDEDYFVILDSEFDHYLVDMKPFVLKLPHKTERQRCALWIKKLCDPVSCGSGLTGRKNRNLYARLLLHMLRKGVLEGPFNHKPDTGSLKTLPTYMSIYFDEP-LTRSQDQRSAAMPDWVSGELEPTESTWSNSPISNTHRKQNLFSNTSPSR---------PLSSSPIKHTLKDD-----VKMAEAHRR-PTISSDDSDFEARFNSWNLGIENPRYLRENPIPLSPIY-KSTLGKSSTVLSEATPAKA-DKEVELRTKVLEAKHQEDTLRMQQKHDAEIQKILDRKNGEIDELKSLYRGKQKEAEETVRRLEKRVQSLLRESQVIRQTKEKQISELKKMSDQSAESLKNEWEKKLHAAVAHMEQEKSELQKKHTENIQELLEDTNQRLAKMEAEYSGQMQATEHIVRELETRVKQLSVEVESGNLLRQKVTQEKAELELQIASISAELQEANQRSTTLQKEMDQMRVHYEEALQKLQARHNADMSHFQQEHAVSAAKASEVIQDLEQTVIHLKQQIQEAESRRHRQLRDQENKWQQEITDMQNSTEKKLQTLQAELEKERADRKRKISKMEDSLRDKEEQLVRVRDSQRHQAQQAESALENFKKQVELSSEKTYADMKQQMEKVEADLIRSKSLREKQCKEFRHQLEELQQKYEQQIVELKLQHEQERTHLLQTHNAEKDSLVQDHQREIDSLDKQTRAAMVQQQTQTQEWRKRDAQTISDLEAQVHSLRKEVLAAHSQRKQQLMELGVLREEERQRSAQDHQAALDRLRAEMEQVRQDLEKTHKAERELAQEKTSSRIKHLEKEYQQKMAKSAQVISELQASLSSVKEDSRQTQQSLERKLQAAQSYWDEEKTQLNRDADQSNKILHERVETLQRQLNAVEKKLMNRELEYQEQITHVRQECELKIKGLMPAELQQELEDTITSLKSQVSFLQKRASVLQEQLDAGHIRR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . *:*: : **:****::************::*********:***:* . *:*: *********:******::* *****.*:*:.*:** **:********* ::.:.. . :* ** ***:. * .:* .: ..:.*. .: : * .:. * ::* *:.*.: : ..:* ****:*.*:**************::*:*:* : * :* *:*:. .: :: :**::::**::***. *:.*::******::****:***.*::*** **: ** *:***:*:***:** *:*:.****:***.**:****:.:**:***:*:****** ***.**::* :***:***.********* ** ***::* * *:*:*:::*** **:** *.*..** ***: *** *** . **** : * . *:** ::: .**: :: *::::::*:. ::****:*::*:* :*::***.: :****:**:* :*::*::*****:: * ..::: *** : **:**:* : * ::** *:*::*::***** ** : ** *****::***:**:***:.***.*.:**:********* *********.*** ***: :*:**********:****:***** *.*******:**:***:.*:** *** ::::.* ** :*****.*:*:*****.**:*:: .:*******:***:*****:**::::*: .:.:*:** *::: :*:*** ** *:: **:.*::*::**** **:***:*:*:***:::**:**:. : * : **:** . . :::** ** ** **: * *::.:*. ..*:...**** ::*** **** ::*** * *:******.*:*******:******.*******:***:* : : **", "identical_positions": 511, "similar_positions": 291, "identity": "53.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120104-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8VHW8-1", "uniprot_id": "CCG5_RAT", "id": "Q8VHW8-1", "name": "Voltage-dependent calcium channel gamma-5 subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTCGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGIILP----------QNQSTEVKMSLHSGLWRVCFLAG---EERGRCFTIEYVMPMNSQMT-SESTVNVLKMIRSATPFPLVSLFFMFIGFILSNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKD----AETYFNYKYGWSFAFAAISFLLTESAGVMSVYLFM----------------------------------KRY------------------------TAEDMYRPHPG--------------------------------------------------------------------FYRPRLSNCSDYSGQFLH---------------------------------------------------------------PDAWIRGRSPSDISSDASLQMNSNYP-ALLKCPDYDQMSSSPC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VHW4-1", "uniprot_id": "CCG5_MOUSE", "id": "Q8VHW4-1", "name": "Voltage-dependent calcium channel gamma-5 subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGIILP----------QNQSTEVKMSLHSGLWRVCFLAG---EERGRCFTIEYVMPMNSQMT-SESTVNVLKMIRSATPFPLVSLFFMFIGFILSNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKD----AETYFNYKYGWSFAFAAISFLLTESAGVMSVYLFM----------------------------------KRY------------------------TAEDMYRPHPG--------------------------------------------------------------------FYRPRLSNCSDYSGQFLH---------------------------------------------------------------PDAWIRGRSPSDISSDASLQMNSNYP-ALLKCPDYDQMSSSPC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UF02-1", "uniprot_id": "CCG5_HUMAN", "id": "Q9UF02-1", "name": "Voltage-dependent calcium channel gamma-5 subunit", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVP----------QNQSTEIKMSLHSGLWRVCFLAG---EERGRCFTIEYVMPMNTQLT-SESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKD----AETYFNYKYGWSFAFAAISFLLTESAGVMSVYLFM----------------------------------KRY------------------------TAEDMYRPHPG--------------------------------------------------------------------FYRPRLSNCSDYSGQFLH---------------------------------------------------------------PDAWVRGRSPSDISSEASLQMNSNYP-ALLKCPDYDQMSSSPC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6W8-1", "uniprot_id": "A0ACD6B6W8_DANRE", "id": "A0ACD6B6W8-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSACGRKALTLLSSVFAVCSLGLLGIAVSTDYWLYLEEGVILP----------LNQSTDMRMSIHSGLWRVCFLAG---EERGRCFTIEYVMPMSVQLT-SESTVSVLKMIRSATPFPLVSLFFMFIGFVLNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMFNRTKS----NEAYFSYKYGWSFAFAAISFLLTESAGVMSVYLFM----------------------------------KRY------------------------TAEEIYQPHPS--------------------------------------------------------------------FYRPRLSNCSDYSGQFLH---------------------------------------------------------------PEAWTRGRSPSDLSSDTSLQMNASYP-ALLKCPDYDQVSSSPC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q2MGK8-1", "uniprot_id": "Q2MGK8_DROME", "id": "Q2MGK8-1", "name": "", "aln": "MRDYPSVPNVFRVASTHSINSENPYNNIRPANVICNTTERPPIAIHQLTTSASIEHSHPSQQAQHQQQQLLHHQQQHHHQQHSPYATLPRGQRLAPQQHQQAGVINTISGSIPATGFSSLAGSFSDLQLNNIGNHSSNSRSNHNSISNNRRQQQQQQQQQQQRLVPHLSRHQPAIEVQQTQQHQQTQQQHVQRQQQQERLASGGAGATDPQGGISNMTTVNGGYLWLITPVAASISVAIVIAALAGPQWLFTEEKLPNANYNGTANFKALDDGAYITKYTKSSLWILCTTLPGLDADSYNCVKIDYFSNEGYQPDPHDSTAAIPYTVTKSCPIFLAAGVFLVISFIVFLIPTCSHQNNLYYFSAGILFIVSGLVMLIGLIAYISILKAEIGSKLRPRSTLQPALIKVSYGQSFFLFVFGFIVTEFVGVLNIFLFINLQEVSYYSRLPCFSVANIHAKLKEGQHPLSDSYKRYKQPGITTASQEGLSSAGQGQQGHQSHHPTHQPHPTAQPPHGILRSGNSRLHQVYDAGRGHPGMTGQIGHSGQTQTLPGACRKHPNAGSNLNLYLHNDLERRFYFEKPAVSKCNLHSRSFAKSLNELCTDTSVSSTHVPAPLLPSAADPLPAPALFADLPQEFPLTRSVSTATEIYPASSSAPAPPSAQMKRKQQRNMATNTNTKISNNPPSSNSQMADQSRLCGLKRGLRKTKDELFQEFCRRAGMRSKPKNIYYISGGDEAEEEEQEDQAKREEVPDDPHRDDDDDADGDDHGFRQFNRMEEEHLYVVGDHAQLVVPRRTSMCVDSMGQPLRRLNSNLSLHTDLSFPGTGGYPGMRMSLPQPADLGQSRTLPRCFLRQSSDSLASQGYPLGSSQQRFSQLMLNQQQNRFVSSTLTLPQVVAPKSQVQWPTAIPSSPSNYSNGYQQHPQPIYPAPTSGSGAPGTTASVSGPPKFQRGYAFDDQQRRSSFVSDAFDLDEIERERRRSHASLFGMGQVRDPYDLINGTAV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: . * *::.* * .:.:: *:: **: ** : . ::.: : :*.** :* : .*..*:*. . * :**. : : .: *: *.: .*:.*.*:: * :..: * :**:**:*** :::**: *** :: *: .: : : :. .** ** : .:.*::** .**:.::**: *** : . ::*** * :* :*:*. :* .* : *.* : :. ::::::. ::. . * : : .* .::.. ", "identical_positions": 67, "similar_positions": 113, "identity": "6.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120104-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UF02-1", "uniprot_id": "CCG5_HUMAN", "id": "Q9UF02-1", "name": "Voltage-dependent calcium channel gamma-5 subunit", "aln": "MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGVIVPQNQSTEIKMSLHSGLWRVCFLA--------------GEERGRCFTIEYVMPMNTQLTSESTVNVLKMIRSATPFPLVSLFFMFIGFILNNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFAFAAISFLLTESAGVMSVYLFMKRYTAEDMYRPHPGFYRPRLSNCSDYSGQFLHPDAWVRGRSPSDISSEASLQMNSNYPALLKCPDYDQMSSSPC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VHW4-1", "uniprot_id": "CCG5_MOUSE", "id": "Q8VHW4-1", "name": "Voltage-dependent calcium channel gamma-5 subunit", "aln": "MSACGRKALTLLSSVFAVCGLGLLGIAVSTDYWLYLEEGIILPQNQSTEVKMSLHSGLWRVCFLA--------------GEERGRCFTIEYVMPMNSQMTSESTVNVLKMIRSATPFPLVSLFFMFIGFILSNIGHIRPHRTILAFVSGIFFILSGLSLVVGLVLYISSINDEMLNRTKDAETYFNYKYGWSFAFAAISFLLTESAGVMSVYLFMKRYTAEDMYRPHPGFYRPRLSNCSDYSGQFLHPDAWIRGRSPSDISSDASLQMNSNYPALLKCPDYDQMSSSPC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7EXE2-1", "uniprot_id": "E7EXE2_DANRE", "id": "E7EXE2-1", "name": "", "aln": "MGLCGRKVLTLLSSVFAVCSLGLLGIAVSTDYWLYLEEGVILPLNQSTEIRMSLHSGLWRVCFLSESPASGTVLPTGKSGDEKGRCFTIEYVMPMNVQMTSESTASVLKMIRSATPFPLVSLFFMFIGFVLSNIGHIRPQRTILAFISGIFFILSGLSLVVGLVLYISSINDEMLNRTKTNEAYFSYKYGWSFAFAAVSFLLTEAAGVMSVYLFMKRYTAEEMYRPHPGFYRPRLSNCSDYSGQFLHPDAWTRGRSPSDISSEASLQMNSNFPALLKCPDYDQMSSSPC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. ****.***********.*******************:*:* *****::*************: *:*:************* *:*****..***********************:*.*******:******:******************************** *:**.***********:******:****************:***************************** **********:********:*****************", "identical_positions": 245, "similar_positions": 24, "identity": "84.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120104-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UBN1-1", "uniprot_id": "CCG4_HUMAN", "id": "Q9UBN1-1", "name": "Voltage-dependent calcium channel gamma-4 subunit", "aln": "MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPP-PRRARGDLTHSGLWRVCCIEGIYKGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKASSSS-PYARMPSYRYRRRRSRSSSRSTEASPSRDVSPMGLKITGAIPMGELSMYTLSREPLKVTTAASYSPDQEASFLQVHDFFQQDLKEGFHVSMLNRRTTPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JJV4-1", "uniprot_id": "CCG4_MOUSE", "id": "Q9JJV4-1", "name": "Voltage-dependent calcium channel gamma-4 subunit", "aln": "MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGPP-PRRARGDLTHSGLWRVCCIEGIYRGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFKTKREFLKASSSS-PYARMPSYRYRRRRSRSSSRSTEASPSRDASPVGLKITGAIPMGELSMYTLSREPLKVTTAASYSPDQDAGFLQMHDFFQQDLKEGFHVSMLNRRTTPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FGK7-1", "uniprot_id": "E7FGK7_DANRE", "id": "E7FGK7-1", "name": "Voltage-dependent calcium channel gamma-4 subunit", "aln": "MAWCERGIQMLLATVGAFVAFSLMSIAIGTDYWLYSRAYICNATNASADETQTQPKKVRGDLTHSGLWRICCIEGLNKGSCYRINHFPDDNDYDTDSSEYLLRIVRASSVFPLLSTILLLLGGLCVGIGRIYNKRNNILLSAGILFVAAGLSNIIGIIVYISSNAGDPSDKRDEDKKNQYNYGWSFYFGALSFIVAEAVAVLAVNIYIEKNKEVRFKARREFIKSTSSSSPYSRMPSFRYRRRHSRSSSRSTEAS--REASPVGMKMISSVPVGEINMYTLTRDPLKSGTDSSYSPDHDSGFLQVHNCFPKDLNDG-----ANRRTTPV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. *:**:****:*.***.*****:*********** *:***.** : *: . *::.***********:*****: :* *:******:***** *****************:************:* ****.::***:*************************:*************:******************:*.*************:***::***:*::*** **:****:*****:*********** *:.**:*:*: .::*:**:.****:*:*** * :*****:::.***:*: * :**::* *******", "identical_positions": 241, "similar_positions": 62, "identity": "73.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120104-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N635-1", "uniprot_id": "MEIOB_HUMAN", "id": "Q8N635-1", "name": "Meiosis-specific with OB domain-containing protein", "aln": "MANSFAARIFTTLSDLQTNMANLKVIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSPAHFVNAASWGNEDYIKSLSDSFRVGDCVIIENPLIQRKEIEREEKFSPATPSNCKLLLSENHSTVKVCSSYEVDTKLLSLIHLPVKESHDYYSLGDIVANGHSLNGRIINVLAAVKSVGEPKYFTTSDRRKGQRCEVRLYDETESSFAMTCWDNESILLAQSWMPRETVIFASDVRINFDKFRNCMTATVISKTIITTNPDIPEANILLNFIRENKETNVLDDEIDSYFKESINLSTIVDVYTVEQLKGKALKNEGKADPSYGILYAYISTLNIDDETTKVVRNRCSSCGYIVNEASNMCT--TCNKNSLDFKSVFLSFHVLIDLTDHTGTLHSCSLTGSVAEETLGCTF-----------------------------VLSHRARSGLKISVLSCKLADPTEASRNLSGQKHV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D513-1", "uniprot_id": "MEIOB_MOUSE", "id": "Q9D513-1", "name": "Meiosis-specific with OB domain-containing protein", "aln": "MAKFFALKNFTALSDLHPNMANLKIIGIVIGKTDVKGFPDRKNIGSERYTFSFTIRDSPCHFVNVSSWGSEDYIRSLSESFRVAECVIIENPLIQRKDTEREEKFSPATPSNYKLLLSENHSMVKVCSPYEVDTKLLSLIHLPVKESRDYYSLADIVANGHSLDGRIINVLAAVRSVGEPKYFTTSDRRKGQRCEVKLFDETEPSFTMTCWDNESILLAQSWMARETVIFASDVRINFNKFQNCMAATVISKTIITVNPDTPEANILLNYIRENKETNVAD-EIDSYLKESVNLNTIVDVYTVEQLKVKALKSEGKADPFYGILYAYISTLNIDDETTKVVRNRCSSCGYIVNEASNTCT--ICNQDSSRLKSFFLSFDVLVDLTDHTGTLHSCSLSGSIAEETLGCTINEFLTMTSEQKTKLKWQLLLERSKIYLKLILSHRARGGLKVTILSCKLADPTEASRNLARQGHT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A2R8RX28-1", "uniprot_id": "A0A2R8RX28_DANRE", "id": "A0A2R8RX28-1", "name": "", "aln": "-MTYAPMGSYVPISDLNINITHSKVVGVIIGKTDSRGFPDRKNVGSERFTFSFTIKDSPEHFINVSAWGNEEYIQALSCRFQIGDCVVIENPLVVTKDYEKEERFCPSTPSSYRLLLTETHSSIRICSDIDTEARILPLFHIPIKDPRDFYSLGDITANGQSLDGHVINILAAVQSVGEEKFFTKSGGCKGQRIEIKLFDDTGRSFPFVCWDKENIRLVQTLTQRETVLFIADARITFDSFRKSMVATAISKTIITVNPDTAEANQLYTFVRELLQSGGLD-DQDFLSGDDVLLDSIRDVMTVSQLKTRSQEN---ADAIHCIIYGFITCFDLGSSPSKIITKRCARCKFRINEESWTCSSDICPNQGQELQAN-ECFDVLVDISDHTGTLQSCNLVGTVAEKTLGCKTEEFLCLSEYQRTSLQWKFLLERCKIYLKVLPSPRRRSGMKADILSCGLADPVEVKQNLASFVV-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :..:***: *::: *::*::***** :*******:****:******:*** **:*.::**.*:**::** *::.:**:*****: *: *:**:*.*:***. :***:*.** :::** :.::::*.*:*:*:*:.:*:***.**.***:**:*::**:****:**** *:**.*. **** *::*:*:* **.:.***:*.* *.*: ****:* :*.**.*:.*::.*.**.*******.*** .*** * .::** ::. * : * :.: *.:* ** **.*** :: :. **. : *:*.:*: :::....:*:: :**: * : :** * *: * ::. ::: .*.**:*::******:**.* *::**:****. : * * *.*:* :*** ****.*..:**: ", "identical_positions": 203, "similar_positions": 157, "identity": "42.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120111-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NE62-1", "uniprot_id": "CHDH_HUMAN", "id": "Q8NE62-1", "name": "Choline dehydrogenase, mitochondrial", "aln": "MWCLLRGLGR-----PGALARGALGQQQSLGARALASAGSESRDEYSYVVVGAGSAGCVLAGRLTEDPAERVLLLEAGPKDVLAGSKRLSWKIHMPAALVANLCDDRYNWCYHTEVQRGLDGRVLYWPRGRVWGGSSSLNAMVYVRGHAEDYERWQRQGARGWDYAHCLPYFRKAQGHELGASRYRGADGPLRVSRGKTNHPLHCAFLEATQQAGYPLTEDMNGFQQEGFGWMDMTIHEGKRWSAACAYLHPALSRTNLKAEAETLVSRVLFEGTRAVGVEYVKNGQSHRAYASKEVILSGGAINSPQLLMLSGIGNADDLKKLGIPVVCHLPGVGQNLQDHLEIYIQQACTRPITLHSAQKPLRKVCIGLEWLWKFTGEGATAHLETGGFIRSQPGVPHPDIQFHFLPSQVIDHGRVPTQQEAYQVHVGPMRGTSVGWLKLRSANPQDHPVIQPNYLSTETDIEDFRLCVKLTREIFAQEALAPFRGKELQPGSHIQSDKEIDAFVRAKADSAYHPSCTCKMGQPSDPTAVVDPQTRVLGVENLRVVDASIMPSMVSGNLNAPTIMIAEKAADIIKGQPALWDKDVPVYKPRTLATQR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BJ64-1", "uniprot_id": "CHDH_MOUSE", "id": "Q8BJ64-1", "name": "Choline dehydrogenase, mitochondrial", "aln": "MWQVLRGWRKGWQSPRGALAWAVQGQPCPPCSRAVASVG---KDEYTFVVVGAGSAGCVLASRLTEDPNHRVLLLEAGPKDLLMGSKRLQWKIHMPAALVSNLCDDKYNWYYHTEPQPGMDSRVLYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWHREGAEGWDYAHCLPYFRKAQRHELGANMYRGGDGPLHVSRGKTNHPLHQAFLQAARQAGYPFTEDMNGFQQEGFGWMDMTVHQGKRWSTACAYLHPVLSRPNLRAEVQTLVSRVLFEGTRAVGVEYIKDGQRHKAYVSREVILSGGAINSPQLLMLSGVGNADDLRKLDIPVVCHLPGVGQNLQDHLEVYVQQACTQPITLHSAQKPLRKVCIGLEWLWSYTGDGATAHLETGGFIRSRPGVPHPDIQFHFLPSQVIDHGRKPTQQEAYQVHVGTMRATSVGWLKLRSANPRDHPVIHPNYLSTETDVEDFRQCVRLSREIFAQEALAPFRGKELQPGSHVQSDKEIDAFVRAKADSAYHPSCTCKMGRSSDPTAVVDAQTKVIGVENLRVVDASIMPSVVSGNLNAPTVMIAEKAADIIKGHPALEDKNVPVYKPQTLDTQR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7EY13-1", "uniprot_id": "E7EY13_DANRE", "id": "E7EY13-1", "name": "Choline dehydrogenase", "aln": "MACFSS----------STRLMSSLCSP-LLHHRYISTVVNKNTPSYSYVIVGAGSAGCVLASRLTENPSDSVLLLEAGPKDKHLGSTRLSWKIHMPAALTYNLCDDRYNWFYHTLPQAHMDDRVMYWPRGRVWGGSSSLNAMVYIRGHAEDYNRWQSEGADGWNYDHCLPYFRKAQTHELGPDRYRGGDGPLHVSRGKTQNPLHYAFIQAGQQAGYPYTEDMNGFQQEGVGWMDMTIHKGQRWSTASAYLRPALSRPNLSTEVRCMVTRVLFDGARARGVEYQQNGQIKKVFAEKEVILSGGAINSPQLLLLSGVGNADELKTLDIPVVQHLPGVGCNLQDHLELYVQHACTQPITLYRAQKPLQMLKIGLEWLLKFTGYGATAHLESGGFIRSRPDVPHPDIQFHFLPSQVIDHGRVSSKIEAFQVHVGPMRSTSVGWLKLKSKDPRDHPILQPNYLSTETDVLEFRECVRLTREIFAQQAFDEFRGPEVQPGPAVQSDAEIDAFVRQKADSAYHPSCTCKMGRPEDRMAVVSPELRVFGVEGLRVVDASVMPSMVSGNLNAPTIMIAEKAADAIKGLPSLHDPGVPVYQPRKHP---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .: . . * :::. .*::*:***********.****:* . ********** **.**.*********. *****:*** *** * :*.**:*******************:*******:**: :** **:* ********** ****.. ***.****:******::*** **::* :***** ***********.******:*:*:***:*.***:*.***.** :*.. :*:****:*:** **** ::** ::.:..:***************:***:****:*:.*.**** ****** *******:*:*:***:****: *****: : ****** .:** *******:******:*.******************** .:: **:*****.**.********:* :*:***:::*********: :** **:*:******:*: *** *:***. :*** ******* ***************:..* ***..: :*:***.*******:***:*********:******** *** *:* * .****:*:. ", "identical_positions": 394, "similar_positions": 118, "identity": "65.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120111-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZIM0-1", "uniprot_id": "D3ZIM0_RAT", "id": "D3ZIM0-1", "name": "Interleukin-17 receptor C", "aln": "MPVPWFLLSLALGRSPVVVSLERLME-PQDTAHCS-----------------------------------------------------------------------LGLSCHLWDGDVLCLPGSIESAPGPVLVPTRLQTELVLRCPQETDCALCVRVVVHLAVHGHWEEPEE----AGKSDSELQGPRNASLQAQVVLSFQAYPIARCALLEVQVPADLVQPGQSVGSAVFDCFEAGLG--AEVRIWSYTKPRYQKELNVTQQLPDCRGLEVQDSIQSCWALP-WLNVSTDGDNVLLILDVSKEQKFGFLLYWDQAQGPLKSLLYKNLTGPQ-------NITLNHTDLVPCLCIQLWSQEPDSVRTSFCPFKKDPRAHRN-LWHMARLRVQSSGSWLLDTPCSLRTEVALCWQAPDQSPCQPLVPPMPQKNVTMNRPFEFPLVKEHPNLCVQVSSWEKVELQECLWADSLGPFKDDMLLVEMKTDLNDTSVCALEPSGCTPLPSVASTVTAPPPPLTWQRAARLGEQLLLDFRTHQCMQLWNDDDLGSLWACPMDKYIHKRWVLVWLACLLLAAALFFFLLLKKDRRK-------------AAPRARPALLLHSADGAYYERLVGALASALSQMPLRVAVDLWSRRELTAHGALAWFHQQRRRTLQEDGVVILLFSPAAVAQCQQWLQLQTVEP-----GPHDALAAWLSCVLPDFLQGQATGRYVGVYFDG----LLHPDTVPALFRVAPLFSLPSQLPAFLDALQGSSSQSPGRPADR---AERVAQALLSALDSCT-----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K4C2-3", "uniprot_id": "I17RC_MOUSE", "id": "Q8K4C2-3", "name": "Interleukin-17 receptor C", "aln": "MPVSWFLLSLALGRNPVVVSLERLME-PQDTARCS-----------------------------------------------------------------------LGLSCHLWDGDVLCLPGSLQSAPGPVLVPTRLQTELVLRCPQKTDCALCVRVVVHLAVHGHWAEPEE----AGKSDSELQESRNASLQAQVVLSFQAYPIARCALLEVQVPADLVQPGQSVGSAVFDCFEASLG--AEVQIWSYTKPRYQKELNLTQQLPDCRGLEVRDSIQSCWVLP-WLNVSTDGDNVLLTLDVSEEQDFSFLLYLRPVPDALKSLWYKNLTGPQ-------NITLNHTDLVPCLCIQVWSLEPDSERVEFCPFREDPGAHRN-LWHIARLRVLSPGVWQLDAPCCLPGKVTLCWQAPDQSPCQPLVPPVPQKNATVNEPQDFQLVAGHPNLCVQVSTWEKVQLQACLWADSLGPFKDDMLLVEMKTGLNNTSVCALEPSGCTPLPSMAST-----------RAARLGEELLQDFRSHQCMQLWNDDNMGSLWACPMDKYIHRRWVLVWLACLLLAAALFFFLLLKKDRRK-------------AARGSRTALLLHSADGAGYERLVGALASALSQMPLRVAVDLWSRRELSAHGALAWFHHQRRRILQEGGVVILLFSPAAVAQCQQWLQLQTVEP-----GPHDALAAWLSCVLPDFLQGRATGRYVGVYFDG----LLHPDSVPSPFRVAPLFSLPSQLPAFLDALQGGCSTSAGRPADR---VERVTQALRSALDSCTSSSEAPGCCEEWDLGPCTTLE--------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NAC3-1", "uniprot_id": "I17RC_HUMAN", "id": "Q8NAC3-1", "name": "Interleukin-17 receptor C", "aln": "MPVPWFLLSLALGRSPVVLSLERLVG-PQDATHCSPVSLEPWGDEERLRVQFLAQQSLSLAPVTAATARTALSGLSGADGRREERGRGKSWVCLSLGGSGNTEPQKKGLSCRLWDSDILCLPGDIVPAPGPVLAPTHLQTELVLRCQKETDCDLCLRVAVHLAVHGHWEEPEDEEKFGGAADSGVEEPRNASLQAQVVLSFQAYPTARCVLLEVQVPAALVQFGQSVGSVVYDCFEAALG--SEVRIWSYTQPRYEKELNHTQQLPDCRGLEVWNSIPSCWALP-WLNVSADGDNVHLVLNVSEEQHFGLSLYWNQVQGPPKPRWHKNLTGPQ-------IITLNHTDLVPCLCIQVWPLEPDSVRTNICPFREDPRAHQN-LWQAARLQLLTLQSWLLDAPCSLPAEAALCWRAPGGDPCQPLVPPLSWENVTVDKVLEFPLLKGHPNLCVQVNSSEKLQLQECLWADSLGPLKDDVLLLETRGPQDNRSLCALEPSGCTSLPSKAST-----------RAARLGEYLLQDLQSGQCLQLWDDD-LGALWACPMDKYIHKRWALVWLACLLFAAALSLILLLKKDHAKGWLRLLKQDVRSGAAARGRAALLLYSADDSGFERLVGALASALCQLPLRVAVDLWSRRELSAQGPVAWFHAQRRQTLQEGGVVVLLFSPGAVALCSEWLQDGVSGPG--AHGPHDAFRASLSCVLPDFLQGRAPGSYVGACFDR----LLHPDAVPALFRTVPVFTLPSQLPDFLGALQQPRAPRSGRLQER---AEQVSRALQPALDSYFHPPGTPAPGRGVGPGAGPGAGDGT-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3B491-1", "uniprot_id": "A0A8M3B491_DANRE", "id": "A0A8M3B491-1", "name": "", "aln": "MDLTSFISKLLLLAGTCVCSMERVTHRPENNITCP----------------------------------------------------------------------QTLLNCTLKRTDPLSAS-DVTCCPASVCHSVTVKPKLCCYN---QDCKPCFWINIQLSFIEDTEDVSDESVYEGSEENSGEDSEYVSESNDHTLCQMKENFNCEEHTDDKVTIAVCYQSAESNEMRCNRLDFTVVSSERHKPLDLTLVEYEDVLFGRKMTISVGSKKTEAEVPTLKTVCSSRDLKDIQQCKGLRIQTETHKGLDKMILISKDEGASQPLYTCMKRGREGKCWPLPNNSIPLASITDCICFQAWKQ--DSERSEICPFEGNKTDFRANVWSQTSVSVVHMK--------TNDNEPMLSWNLT--SPCR-------------ISPELWPCLLQADGVCKEVKGFR--QKCCNTWTENSTKLWASGTFVNIPSE-NQQPLCIM---------------------------LKVDEEIMQYCQHPLERQYWSLLLLLPLIG----------VCLTVVGGLLLVNKIKWSLSEWDRCYS--------------QDTRGQVLLLHSPATN--SQLVRKIGQLLSELGFRVFLDLWNPAELGSCGPTAWLHSKLDHIKKHGGKALLLLSQSTLQRADLFWDAAVERQNNPEANCSDTLASALGCIFADRQKGGAVQRFILVQIDSPELLVNEENDLPKLLRGLPLYKLPSQAQGLLTELCLEKPNNVNEKLKKMWWMKRAQRKLATGMQNFWKMTRVRTESMNTQTDSLSVDMEDTEERVCLRHELH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :. *: .* * .. * *:**: *:: *. *.* * * *. . .: .*..* .. ::.:* ** *. : ::*:. . : .: * :. : .. .* . : .*. : :*. : . . .. : :: : . : . * .*:. * : . . :. .: : .: ::. : * ::.. .: :. : .. :. * : :: :.:. *:*:* * ** * .:***. : .: :* : : : : *.*. . .**: : : .:* :*. . : *::. : . ::: :: .:* : ::.* :: : * *. : .* . *. :. **:. : * . . .***:*. .:** :.. *.:: :** :***. ** : *. **:* : : :..* .:**:* .:: .. : : . . *:: : *.*::.* :* * :: . :* : . : :* :* *::.**** :* * . .. .: ::. : * ..::. ", "identical_positions": 97, "similar_positions": 223, "identity": "11.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120112-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZVW7-1", "uniprot_id": "I17EL_HUMAN", "id": "Q6ZVW7-1", "name": "Interleukin-17 receptor E-like protein", "aln": "MLAGQALAFLGLTWGTFQSLAIPRITECGLSCSQGFACRSHRNRNIFNSFCRPRPVSMSRSVLEALTSSTAMQCVPSDGCAMLLRVRASITLHERLRGLEACAMSLDTQETQCQSVWVARASHRQQGGQQLQVHFGCFAVSVAQHLYVTLRTIPHFCGVQLDQRHLVEDCGEEDVGRSVPDCLAGKLSYWVDRRRKAILVQVPRASGSPDYYLRLCLKR-FTCEDAGAPVRVTANSVSQAVFLPYSQELPCLCLEGWSATPDAVRIQICPFENDTEALEVLWDTVYYHPESQTLSWEPACPVSGHVSLCWRPGPGAGCRKLQQSSQLVHRRVQYPLVDTQPQLCLKFSTSWGSWVRCPFEQRRFPTWKMTIQPSPTKGHLRVTFFSSSPAHFQVHLCHRRKSQLPACQRTLQASPLPSASGDLAAAPAFAFLDLPREEACAPGICIQGWRTDVHFSVPQQLCNLRSSGCPSLRGRRRPRTRPRPPTAGWAWR------ALNRRLGGGNGETIRP-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RS12-1", "uniprot_id": "A0A8M1RS12_DANRE", "id": "A0A8M1RS12-1", "name": "", "aln": "MICFWLPLLLLLQKHTVQMERIERNQDCGWNCSEGLQCKPRAYSPLSAFHCRNQPISS--AVFNDVMLSTVLACEERK-CSLQLRMATSVNVTGNIRGVSVCADSAGMIG-HCQIYTFGRVGGFNVTGKQVDVRFKCVPVRPGQHLFVTLKTIPNYCKAMWSQRHLVPDCRHEGVRDEVAECITGKLAYTVDKAKKLFSVTVTGAPEDTEYNLRLCHKRNVICAGEGTHKTVKPQHLQRSVQLHYSKALPCLCIEGWPAKVDARRVQVCPFKNN---FEELWSGITYDLRKGELIWEPLCPVKVLVSLCHADGSKS-CRDIGEAFHSDGQKVVFSSVDPHPALCTKFTTEVGTWIRCPFSEGNFSVWTAKMAFK--DGQQWAEISAWVKANFSVSICEMK----PSQCKSIEGSNLKTLSVDKTKPTVFNLS----ESACKVCVCIQVQRVDVLFSVPVLQCDLQCPNWCHDPDSDHSEDIEMILLPAVIFLTVILAVVLFGRLTIKDGDEKKGRLWKKLRCQGMNQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:. :* * *.* * * :** .**:*: *:.: : .** :*:* :*:: : **.: * . *:: **: :*:.: .:**:..** * . :** ..*.. : *:*::*:* *..* .***:***:***::* . .***** ** .*.* .*.:*::***:* **: :* : * *. *. ..:* **** ** . * . *: *..: :.::* * **: *****:***.*. ** *:*:***:*: :* **. : *. .. * *** ***. **** *. : **.: :: : ::* :. **.:* ** **:*. *:*:****.: .*..*. .: . .*: . : : *:*.* :*. : *: ::::.* * : * * : ...* : *.** :*** *.** **** *:*:... . :.. .. : .* ** :*: : ", "identical_positions": 166, "similar_positions": 162, "identity": "31.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120117-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O70324-1", "uniprot_id": "MOT8_MOUSE", "id": "O70324-1", "name": "Monocarboxylate transporter 8", "aln": "---------------------------------------------------------------------MALPSPASEEAEGPCQEANQEYQEPVCSPVPEPEPEPEPEPEPDPEPVPVPPPEPQPEPE-------------------------------------PQPLPDPAPLPELGFEAEPVQEPEPTPTVETRGTARGFQPPEGGFGWIVVFAATWCNGSIFGIHNSVGILYSMLLEE-EKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIKMLGDKIK-LAQTFQVLSTFMFVLTLLSLTYRPLLPS---------SQDTPSKRGAHTLRQRFLVQFRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEDKFKEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFG---DYHVAFYFAGVPPIIGAVILFFVP-------LMHQRMFK--KEQRDSSKDKMLSHDPDPNGELLPGSPTPEEPI-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8K1P8-1", "uniprot_id": "MOT8_RAT", "id": "Q8K1P8-1", "name": "Monocarboxylate transporter 8", "aln": "---------------------------------------------------------------------MALPSPASEEAEGPCQEANQEYQEPVCSPVPEPEPEPEPEPEPEPEPVPVPPPEPQPEPE-------------------------------------PQPLPDPAPLPVLGFEAEPVQEPEPTPTVETRGTARGFQPPEGGFGWIVVFAATWCNGSIFGIHNSVGILYSMLLEE-EKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIKMLGDRIK-LAQTFQVLSTFMFVLTLLSLTYRPLLPS---------SQDTPSKRGAHTLRQRFLVQFRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEDKFKEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFG---NYHVAFYFAGVPPIIGAVILFFVP-------LMHQRMFK--KEQRESSKDKMLSHDPDPNGELLPGSPTPEEPI-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P36021-1", "uniprot_id": "MOT8_HUMAN", "id": "P36021-1", "name": "Monocarboxylate transporter 8", "aln": "---------------------------------------------------------------------MALQSQASEEAKGPWQEADQEQQEPVGS----PEPESEPEPEPEPEPVPVPPPEPQPEP---------------------------------------QPLPDPAPLPELEFESERVHEPEPTPTVETRGTARGFQPPEGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEE-EKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIRMLGDKIK-LAQTFQVLSTFMFVLMLLSLTYRPLLPS---------SQDTPSKRGVRTLHQRFLAQLRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEEEFSEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFG---DYHVAFYFAGVPPIIGAVILFFVP-------LMHQRMFK--KEQRDSSKDKMLAPDPDPNGELLPGSPNPEEPI-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G8XYX6-1", "uniprot_id": "MOT8_DANRE", "id": "G8XYX6-1", "name": "Monocarboxylate transporter 8", "aln": "---------------------------------------------------------------------MHSESDDNTAGGTPGSEDPQ------------AEESSSPAEEFEEQERKLAPEDS------------------------------------------------TVQLIHTGCTD---KRPATPPGAHP---GQGFVPPEGGFGWVVVFAATWCNGSIFGIQNSFGILHMMLVKHHEKQPDQASQFKVAWVGALAMGMIFFCSPVVSMFTDHFGCRKTAVCGAFVAFIGLLTSSFATTLGLWYFTYGILFGCGSSFAFQPSLVILGHYFRQRLGLANGVVTAGSSLFSMGLPVLLKKVVEPLG-LPRTFQILSIFMLVQALLALAFKPLLPSGMCPMPGMALDGGPSTPESASRWQKGLAKIRRYFNVRVFSILTYRIWAFGVATAVLGYFVPYVHLLNFVKEQFGDTQREWLLLVCIGASSGVGRLLFGKIGDLIPGVKKIYMQVASFILLGVMSMMIPQCAVFEGLVVVFVLMGLCDGCFITIMAPIAFELVGPMQASQAIGYLLGLMAIPMTAGPPIAGLLHDHFG---NYHVAFYLAGVPPIVGGIVMFFVP-------LVHQRMQKRRKETDDPSMDKMLKN--CSNGDMLPGYTDMETHI-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P36032-1", "uniprot_id": "MCH2_YEAST", "id": "P36032-1", "name": "Probable transporter MCH2", "aln": "----------------------------------------------------------------------------------------------------MSEERHEDHHRDVENKLNLNGKDD-----------------------------------------------------------------------INGNTSISIEVPDGGYGWFILLAFILYNFSTWGANSGYAIYLAHYLEN--NTFAGGSKLDYASIGGLAFSCGLFFAPVITWLYHIFSIQFIIGLGILFQGAALLLAAFSVTLWEIYLTQGVLIGFGLAFIFIPSVTLIPLWFRNKRSLASGIGTAGSGLGGIVFNLGMQSILQKRG-VKWALIAQCIICTSLSTIALMLT--------------------RTTHQGLRQHKRSYKFELLDYDVLSNFAVWLLFGFVSFAMLGYVVLLYSLSDFTVSLGYTSKQGSYVSCMVSVGSLLGRPIVGHIADKYGSLTVG--MILHLVMAILCWAMWIPCKNLATAIAFGLLVGSIMGTIWPTIASIVTRIVGLQKLPGTFGSTWIFMAAFALVAPIIGLELRSTDTNGNDYYRTAIFVGFAYFGVSLCQWLLRGF-----IIARDEIAVREAYSADQNELHLNVKLSHMSKCLFRYKQLPRRV-----------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53918-1", "uniprot_id": "ESBP6_YEAST", "id": "P53918-1", "name": "Uncharacterized transporter ESBP6", "aln": "MSTHSNDYFSASSGMVSETSSEVSSINSSQPVSFSKASIAAPVPCSDLHSTKSNDASRKLSISRTLTNRLNDIKKAVDDDNLQTEENSADVNKILESRFDVADAIRLQHNESVQSKLNIPVTHTTTAGASLSAPSSSAFSASSIQNDTTEHKASMDSKLMRNRLYPASTKHSGKDLEAQGITEFEPDEPTVKKVFTNKSTGQLELPPDGGYGWVVTFCVFLTMFSTWGCNASFGVDLAYYLNH--DTYPGASKYDYALIAGLTVFLGQLLSPLVMALMRIIGLRTTMLFGDAVMLAAYLLASFTTKLWQLYVTQGFMVGCSISLIFVPATTVLPGWFLKKRAVAMGVSLLGTGAGGVVYGLATNKMLSDFGNTRWCLRIIGISCSISVLVAIALLKERNP--------------TPAIGLKSPRAMFEQLKAMFSLKVITKPFVVLIALWFMFALFAYNMMVFTLSSYAISKGLSSHDASTLTAILNGSQSIGRPLMGLAGDKFG--RANVTIVLTTLLTIYMFAFWIPAHTFVQLIFFSILVGSCVGVANVMNTVLIADMVKPEEFLPAWAFVNYCGAPFLLVCEVIAQALTVEKDKSNPYLHAQIFCGCCFIAALILISILREYSIRMKLTERQAMTNEKLKEWKASEYDTDSADEDWGKLKERKTKYDLLLGPGIKKYFLRMVYPMKV", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . . : . . *:**:**.: :. * :* : . .: ::. . : . * :..*:. : :*:: : :. : * . . ::*: .* *.* *.:.* . :: * *: .:: :* .: .:* *: *:. .: . . : . : ::: : :. *: : . * :.* : * .:. . : : :. . :** : * .* : :: : . : : . :::* * : : :* : : . * . *. * * : : * : : :: : : : : .. : ", "identical_positions": 39, "similar_positions": 125, "identity": "5.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120120-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AU34-1", "uniprot_id": "A2AU34_MOUSE", "id": "A2AU34-1", "name": "", "aln": "------------------------MASPPGLELKTLSNGPQVPRRAASQGPVAPPRMGVENACFFSEEQETHFQNPGDARLGNAPSPPGGVPSLSRSQRDDLSLHSEEGPGLEPVSRPVDYGFVSALVFLVSGILLVVTAYAIPREARVNPDTVTAREMERLEMYYARLGSHLDKCIIAGLGLLTVGGMLLSVLLMVSLCKGELYRRQTFVPGRGSRKTYGSINLRMRQLT-GDGGQVLVENEVVQVSETSYTTQGS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NUR3-1", "uniprot_id": "TM74B_HUMAN", "id": "Q9NUR3-1", "name": "Transmembrane protein 74B", "aln": "MPPAQGYEFAAAKGPRDELGPSFPMASPPGLELKTLSNGPQAPRRSAPLGPVAPTREGVENACFSSEEHETHFQNPGNTRLGSSPSPPGGVSSLPRSQRDDLSLHSEEGPALEPVSRPVDYGFVSALVFLVSGILLVVTAYAIPREARVNPDTVTAREMERLEMYYARLGSHLDRCIIAGLGLLTVGGMLLSVLLMVSLCKGELYRRRTFVPGKGSRKTYGSINLRMRQLN-GDGGQALVENEVVQVSETSHTLQRS------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WFQ7-1", "uniprot_id": "X1WFQ7_DANRE", "id": "X1WFQ7-1", "name": "", "aln": "------------------------MESLNAVELRELGERPQ-----ASSGPRPST--GIENASFEDEDPGSRIRVTSRASGPSFTSIDSQSNPLP-IQREVPSPRSEDEPELEYNDHSVDYGFIFALVFLVSGIILVVIAYTIPREAKVNPDQVTARQMEKLEMYYAQLGSHLDKCIIAGLGLLTLGGMLLSVLLMVSICKGELYRRRTFA--RRPMKSYGSINMRMRQLAEGDGRDTLVECEPNTTADAANGNQVPAGTLNT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * .:**: *.: ** *. ** ... *:***.* .*: :::: .. : . .* . .*. **: * :**: * ** .:.*****: *********:*** **:*****:**** ****:**:******:******:**********:************:********:**. : . *:*****:***** *** :.*** * .:::: * . ", "identical_positions": 123, "similar_positions": 55, "identity": "46.77%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120126-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60829-1", "uniprot_id": "PPR1B_MOUSE", "id": "Q60829-1", "name": "Protein phosphatase 1 regulatory subunit 1B", "aln": "MDP----------KDRKKIQFSVPAP-PSQLDPRQVEMIRRRRPTPAMLFRVSEHSSPEEEASPHQRTSGEGHHPKSKRPNPCAYTPPSLKAVQ-----HLQTISNLSENQASEEEDELGELRELG-YPQEDDEEDE--DEEEDEEEDSQAEVLKGSRGTVGQKPTCGRGLEGPWERPPPLDEPQRDGNSEDQVEGRATLSEPGEEPQHPSPP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UD71-1", "uniprot_id": "PPR1B_HUMAN", "id": "Q9UD71-1", "name": "Protein phosphatase 1 regulatory subunit 1B", "aln": "MDP----------KDRKKIQFSVPAP-PSQLDPRQVEMIRRRRPTPAMLFRLSEHSSPEEEASPHQRASGEGHHLKSKRPNPCAYTPPSLKAVQRIAESHLQSISNLNENQASEEEDELGELRELG-YPREEDEEEEEDDEEEEEEEDSQAEVLKVIRQSAGQKTTCGQGLEGPWERPPPLDESERDGGSEDQVEDPA-LSEPGEEPQRPSPSEPGT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F7T1-1", "uniprot_id": "E7F7T1_DANRE", "id": "E7F7T1-1", "name": "Protein phosphatase 1 regulatory subunit 1B", "aln": "MDPSSPSEGPVEPKERRKIQFAVPATEPTQLDPRQVEMIRRRRPTPATLFKVADQTSPEDDITSHQWVVGENGILKPKRINPNIYQPPSLKAVQ----------------QMAEAQ-----MQKLGVYPHVEEEGEEPVHRGGAELCSSCTTESQEQRSTPEKQ----SGMR-KTEATAPTDEEEEEEEEEEEEDEEKEEEEADDMAREESRNLD--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *:*:****:***. *:****************** **::::::***:: :.** . **. *.** ** * ******** * :* : :::** **: ::* :* .. * .* : : * : :: *:. * ..* ** :.: .*:: : .*..: .:. * ", "identical_positions": 73, "similar_positions": 53, "identity": "33.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120201-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BLG2-1", "uniprot_id": "LPAR4_MOUSE", "id": "Q8BLG2-1", "name": "Lysophosphatidic acid receptor 4", "aln": "MGDRRFIDFQFQDLNSSLRPRLGNATANNTCIVDDSFKYNLNGAVYSVVFILGLITNSASLFVFCFRMKMRSETAIFITNLALSDLLFVCTLPFKIFYNFNRHWPFGDTLCKISGTAFLTNIYGSMLFLTCISVDRFLAIVYPFRSRTIRTRRNSAIVCAGVWILVLSGGISASLFSTTNVNNATTTCFEGFSKRVWKTYLSKITIFIEVVGFIIPLILNVSCSSVVLRTLRKPATLSQIGTNKKKVLKMITVHMAVFVVCFVPYNSVLFLYALVRSQAITNCLLERFAKIMYPITLCLATLNCCFDPFIYYFTLESFQKSFYINTHIRMES-LFKTETPLTPKPSLPAIQEEVSDQT--TNNGGELMLESTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99677-1", "uniprot_id": "LPAR4_HUMAN", "id": "Q99677-1", "name": "Lysophosphatidic acid receptor 4", "aln": "MGDRRFIDFQFQDSNSSLRPRLGNATANNTCIVDDSFKYNLNGAVYSVVFILGLITNSVSLFVFCFRMKMRSETAIFITNLAVSDLLFVCTLPFKIFYNFNRHWPFGDTLCKISGTAFLTNIYGSMLFLTCISVDRFLAIVYPFRSRTIRTRRNSAIVCAGVWILVLSGGISASLFSTTNVNNATTTCFEGFSKRVWKTYLSKITIFIEVVGFIIPLILNVSCSSVVLRTLRKPATLSQIGTNKKKVLKMITVHMAVFVVCFVPYNSVLFLYALVRSQAITNCFLERFAKIMYPITLCLATLNCCFDPFIYYFTLESFQKSFYINAHIRMES-LFKTETPLTTKPSLPAIQEEVSDQT--TNNGGELMLESTF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7A2-1", "uniprot_id": "A0ACD6B7A2_DANRE", "id": "A0ACD6B7A2-1", "name": "", "aln": "-----------------MASLVLNETGMENCGIDDSFKYNLYGVVYSVAFVLGLATNCASLFVFCCRMKMRNETTLFMTNLALSDLVFVFTLPFKIFYNVNRHWPFGDTLCKISGGAFITNIYGSMLFLTCISVDRFLAIVYPFRSLSIRTRRNAGIVCATIWLLILGGGMSVTFFSSTNQSKTSTTCFEGFSKKTWKTYLSKITIFIEVMGFLIPLLINLACSSMVLRTLRQPATLCQIGTNKERVLRMIVVHLAIFIVCFVPYNTVLFVYAMVRTRALASCWVERLARTLYPITLCIATFNCFFDPVVYYFTSESFQKSLTTGKNQAMQEDGLQNECPLSNKE-----KTDVADLYTLTRNGKNQVGETQF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : * *. :.* :******** *.****.*:*** **..****** *****.**::*:****:***:** *********.*************** **:*************************** :******:.**** :*:*:*.**:*.::**:** .:::*********:.**************:**:***::*::***:******:****.******::**:**.**:*:*:*******:***:**:**::*::.* :**:*: :******:**:** ***.:**** ******: . : *:. ::.* **: * : :*:* *.** : : *: *", "identical_positions": 228, "similar_positions": 86, "identity": "61.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120201-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JXM5-1", "uniprot_id": "A0A0G2JXM5_RAT", "id": "A0A0G2JXM5-1", "name": "Polymerase delta-interacting protein 3", "aln": "-MADISLDELIRKRGTATKGRLSVRPGIGGVRSRVGIQHSLLSQPARTATFQQRFDA-------RQKIGLSDARLK-------LGVKD---AREKLLQKDARFRIKGK----------------VQDAREMLNSRKQQ-------NTVPQKPRQVADAREKISLKRRSP------ATFTSPP-----------IGTVTPA---LKLTKTIQVPQQKAMVPLHAHP----------AGMRINVVNNHQAKQNLYDLDED-----------DDIVAPVPTKQMKFAAPGSLVHHTTGMSSPKLSMSKTLPLTK----VVQNDAYTAPVLPSSVR-------TKALTNMSRTLVN-------KEELPKELPPAEPVLSPLEGTKMTVNNLHPRVTEEDIVELFCVCGALKRARLVHPGVAEVVFVKKDDAITAYKKYNNRCLDGQPMKCNLHMNGNVITSDQPILLRLSDSP----SVKKESELPRRGNPVSS-NPPAEVDPDTILRALFKSSGASVTT--------------QPTEFKIKL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG81-1", "uniprot_id": "PDIP3_MOUSE", "id": "Q8BG81-1", "name": "Polymerase delta-interacting protein 3", "aln": "-MADLSLDELIRKRGTAAKGRLSVRPGIGGVRSRVGIQHSLVNQPARTATFQQRFDA-------RQKIGLSDARLK-------LGVKD---AREKLLQKDARFRIKGK----------------VQDAREMLNSRKQQ-------GTVPQKPRQVADAREKISLKRRSP------AAFTSPP-----------IGTVTPA---LKLTKTIQVPQQKAMVPLHAHP----------AGMRINVVNNHQAKQNLYDLDED-----------DDIVVPVPPKQMKFAATGSLVHHMTGLSSSKLSMSKALPLTK----VVQNDAYTAPVLPSSVR-------TKALTSMSRTLVN-------KEEPPKELPPAEPVLSPLEGTKMTVNNLHPRVTEEDIVELFCVCGALKRARLVHPGVAEVVFVKKDDAITAYKKYNNRCLDGQPMKCNLHMNGNVITSDQPILLRLSDSP----SVKKESELPRRGNPASS-NPPAEVDPDTVLRALFKSSGASVTT--------------QPTEFKIKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BY77-1", "uniprot_id": "PDIP3_HUMAN", "id": "Q9BY77-1", "name": "Polymerase delta-interacting protein 3", "aln": "-MADISLDELIRKRGAAAKGRLNARPGVGGVRSRVGIQQGLLSQSTRTATFQQRFDA-------RQKIGLSDARLK-------LGVKD---AREKLLQKDARFRIKGK----------------VQDAREMLNSRKQQ-------TTVPQKPRQVADAREKISLKRSSP------AAFINPP-----------IGTVTPA---LKLTKTIQVPQQKAMAPLHPHP----------AGMRINVVNNHQAKQNLYDLDED-----------DDGIASVPTKQMKFAASGGFLHHMAGLSSSKLSMSKALPLTK----VVQNDAYTAPALPSSIR-------TKALTNMSRTLVN-------KEEPPKELPAAEPVLSPLEGTKMTVNNLHPRVTEEDIVELFCVCGALKRARLVHPGVAEVVFVKKDDAITAYKKYNNRCLDGQPMKCNLHMNGNVITSDQPILLRLSDSP----SMKKESELPRRVNSASSSNPPAEVDPDTILKALFKSSGASVTT--------------QPTEFKIKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQ58-1", "uniprot_id": "A0A8M3AQ58_DANRE", "id": "A0A8M3AQ58-1", "name": "", "aln": "-MADLSLDEVIRRRSFTARG-ASKRPVYGRGAGPLNMAFDAR-QKIGSGDVRQRLGVGGASGGKRLQISASGAAVQTLSRPSVFPVKD---AREKLGQKDARLRLRGRGGGTSAVQSRGGGASAMQDARLMINLRKQQQQQPSASGPAPASARPSGPGVPHVHIHNTSP------RAHTLTTRVGVALQPGGGITKVVDARDRLSLKRSVPTTSNQSAASLKITKTIQQRPVGMTSGIRINVPSAAPPRVCAAAEDEDE----------DDVSAVIPSKQMKITAASSLQTRAG-------PVSLSAPITK----VVKNDSYTPPSVSVPPARPAPRPPTQSLQPVSRTTVTTQPAG--RDTSAQTHTPTQPVFSPLEGTKITVTNLHPRVTEEDIVELFCVCGALKRARLAKVGVAEVVFVRKEDAVSAYRKYNNRCLDGQPMKCNLHMQGSVITSDQPILLRLSDTPGSPLSAQKASSSSSSRSSKSS--SAAEVDPQTILKALFKSSSSSSSSSSQTASSASETPAAHATAFRIKI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWQ6-1", "uniprot_id": "Q9VWQ6_DROME", "id": "Q9VWQ6-1", "name": "RRM domain-containing protein", "aln": "MDIDLSLDEIIERKRGQRGYRPLDRKFNANFSKPRQLLNKPFFKPSGARGSHSDTPAKRTFDARNTIAAKTRAKIADARDLINKSVRDSGIDARQLLLERKKARSAGP--------------ILIDDEEESFEPSHRARGKGVHIGQFGHRLSMSNHADGTIQAKWDSDDGVVELGNHMLSGLRRTFDPRSHKPGKPFAPRRYIDLDNMQDLEDEEISRTLHLGQMKQASPRYSIGGLDLNRGDDVEMSMAPLNNKIDNNAFSIYEAARNRIERPSLTNRLVVGRSNTTKEPLERRHRDTASTSKLPESLRSRLFVGKRDPHISHGIYANENRRKAVGGGGARDSDSGTDSDGDAAAPSKNKRRSPSPLSLRTSNTKDGYRLLVSNLHTNVTTADIRELFSDIGPVYDARVVRPGTAEVIYKSLEHAEKAVDTYHHRQFDDQPMHCVLVNPHSSRRS-----------------VHKAS--SRTVTTNSS---GVEVDIDALHSVLFRVR-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VWQ3-1", "uniprot_id": "Q9VWQ3_DROME", "id": "Q9VWQ3-1", "name": "RRM domain-containing protein", "aln": "MDIDLSLDEIIERKRGQRGYRPLDRKFNANFSKPRQLLNKPFFKPSGARGSHSDMPAKRTFDARNTIAAKTRAKIADARDLINKSVRDSGIDARQLLLERKKARSAGP--------------ILIDDEEESFEPSHRARGKGVHIGQFGHRLSMSNHADGTIQAKWDSDDGVVELGNHMLSGLRRTFDPRSHKPGKPFAPRRYIDLDNMQDLEDEEISRTLHLGQMKQASPRYSIGGLDLNRGDDVEMSMAPLNNKIDNNAFSIYEAARNRIERPSLTNRLVVGRSNSTKEPLERRHRDTVSTSKLPESLRSRLFVGKRDPHISHGIYANENRRKAVGGGGGSDSDSGTDSDGDAAAPSKNKRRSPSPLSLRTSNTKDGYRLLVSNLHTNVTTADIRELFSDIGPVYDARVVRPGTAEVIYKSLEHAEKAVDTYHHRQFDDQPMHCVLVNPHSSRRS-----------------VHKAS--SRTVTTNSS---GVEVDIDALHSVLFRAR-----------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:****:*.:: * . : : : :. . . . : * : *:* .:* : : * * ::* . :: :: . : : * . . . . :.* . .:: .*: .*: :* . . * : .::: . .. . * : * :.*.: . : . * * :: . . : . .. :* :: *.***..** ** ***. *.: **:.: *.***:: :.* .* .*::* :*.***:* * . * :* * . .. ** .*** ::: .**: ", "identical_positions": 64, "similar_positions": 108, "identity": "11.87%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120201-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2ARK0-1", "uniprot_id": "FA83C_MOUSE", "id": "A2ARK0-1", "name": "Protein FAM83C", "aln": "MQGCQAGASIFFLIAANPDANHGASGGLGSRWIRTFSRIAPAGTQGMAGPLRSRVEELKRPWWRESSPLVLQHSEAARLAADALLERGEAAYLQVISEERELPFLSALDVDYMISHVRGVPELSEAQGSETLGQD-LSMLSEVTSGTYFPMASDLDPPDLDLGWPEVPQATGFSPTQAVVHFQRDKGKSIKDLLRFLFSQAQTVVAVVMDVFTDMELLCDLMEASSRRGVPVYLLLAQEHLKYFLEMCYKMDLNGGHLVNMRVRSTCGDTYCSKAGRRFTGQALEKFVIIDCEQVVAGSYSFTWLCSQAHTSMVLQLRGHIVEDFDREFRCLYAESQPVEGFCS-NEDPLMPQVPRPPPVTLAFGPAVPSATGSSPSSNSLSSIKHSPLLARSSYLALPGGGGRNDMGMGSSSPGPAYHEAGGQPSLYRQLSDPNHISPPGPYRANLSKLGASPWSQSSPALNHSSTSPLTLAVGSPLLPSSRPLLHFTRGVPALSRLPENGLPASQDPSLPRGRWVPGTALETVEEK--KVSLSQSHDHLDRLSPFSKAGEAGGPNSRVTPDSSSLQHRELALDDRRLSLSHSHSQLDLLSQGQ---GVLESGSLRPGELSLENRKLSLNHNHGQLDLLPQNPKPQAPKIPSDAYSSAGPSKPSLDDRRQTLGHSQLDLITKFGPFRSEGPGPSCPPEPSPVRMAGVGSADEKRLTLGHSKLDLITKYHQLQGARQKPEPGIPGAPVSGHQNGSSNDLFAPEKRLTLGHSKLDLITKYNKSKFKQLRSRFES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQN1-1", "uniprot_id": "FA83C_HUMAN", "id": "Q9BQN1-1", "name": "Protein FAM83C", "aln": "-----------------------MFGGPGP---------GVLGAQGMAGPLRGRVEELKLPWWRESSPLVLRHSEAARLAADALLERGEAAYLRVISEERELPFLSALDVDYMTSHVRGGPELSEAQGQEASGPDRLSLLSEVTSGTYFPMASDIDPPDLDLGWPEVPQATGFSPTQAVVHFQRDKAKNIKDLLRFLFSQAHTVVAVVMDIFTDMELLCDLMEASSRRGVPVYLLLAQEHLRHFLEMCYKMDLNGEHLPNMRVRSTCGDTYCSKAGRRFTGQALEKFVLIDCEQVVAGSYSFTWLCSQAHTSMVLQLRGRIVEDFDREFRCLYAESQPVEGFCG-GEDPLSPRALRPPPVALAFRPDVPSPTSSLPSSTSLSSIKQSPLMGRSSYLALPGGGDCSDTGVVSSSLGPARREASGQPSLHRQLSDPNHGSPPGLYRANLGKLGAYPWSQSSPALNHNSTSPLTLAVGSPLLPRSRPLLQFHRGAPALSRFPENGLPGSQEPSPLRGRWVPGTTLETVEEKEKKASPSQSRGQLDLLVPFPRAREVGDPDSGVTPNSGPLRPGEQAPEDRRLSPSQADSQLDLLSRALGTGGAPELGSLRPGDRALEDRRLSLNQSRGQSDLLMQYPKAQGSRVPLETNSSARPARRAPDERRQTLGHSQLDLITKFGPFRGEGPGPNGLPISSPARTAGAGSGDEKRLTLGHSKLDLITKYHQLHGARQGTEP---GGPKGGHLNGGNSDLVRDEKRLTLGHSKLDLITKYNKSKFKQLRSRFES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXI7-1", "uniprot_id": "E7EXI7_DANRE", "id": "E7EXI7-1", "name": "", "aln": "---------------------MISSEALRP---------TPNAARKPLGKLASRLEEVKNP-WKQLSALELSHNETARLATDALLEHGEKEYKKVLHEEKELNFLSALEIRYITENVAKVG--DADSGSNGVDLEEGDAVSELTSGTYFPMMSDEEPPMLELGWPEL--STRMGPTEANIYFQRDKTKNVKDHIRSLISKAKKVIAIVMDIFTDVDLFCDLMEASNKRRVPVYILLDEKNLSHFLNMCSELDVQNSHLSNMRIRSVCGDTYCTKSGKKFTGQVQEKFMIIDCEEVIAGSYSFTWLSGQVHSNLVMHFSGHLTDCFDREFRCMYADSDIIERFHNPDEDGLPSYSYSYNMPAPNFGLDVLADYGSRERVYSENSSSQS-----------------------SSSVSSIKAAPPGTKSVYKVNHDKKSQEN----------------TQKTPDKKDATS----------------PVLHMP-------------------LAAHIGRGFPNEIHQTAERS----SLGQSGG-----AEWSKIGNTDYLRSNIGGQTSKIQSLGLYSSPKPPSPTQQDNKIS------------------------PKHRLTSPFLSKFTDLFTTKEKD------LHAFQKVPPPRSSPFGGP---DLSQNEPESKQGPPP---PGP--MPIDRMGPDKGIHRRDEKRMTLGHSKLDLVAQYNKMNKSKQ-------------------------------VYSRFELKNNLPQ------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . .:: * * .*:**:* * *:: *.* * *.*:****:*****:** * :*: **:** *****:: *: .:* . .*.: . : . :**:******** ** :** *:*****: :* :.**:* ::***** *.:** :* *:*:*:.*:*:***:***::*:*******.:* ****:** :::* :**:** ::*::. ** ***:**.******:*:*::****. ***::****:*:*********..*.*:.:*::: *::.: *******:**:*: :* * . .** * . : * * : .* * .* .:* *** .. . * *::: * : . :*.:* :. :: *:*:: : ** .*. :*.*.. * .** . :.: :.. * : ::. :: . : * :: ..::. .::*: **: * .: ... *.: : . ** : :* ** *** * * ****:*********:::*:::: ::* :*:::* .: : ", "identical_positions": 216, "similar_positions": 185, "identity": "27.59%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120203-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IUR6-1", "uniprot_id": "CRERF_HUMAN", "id": "Q8IUR6-1", "name": "CREB3 regulatory factor", "aln": "------------------------------------MPQPSVSGMDPPFGDAFRSHTFSEQTLMSTDLLANSSDPDFMYELDREMNYQQNPRDNFLSLEDCKDIENLESFTDVLDNEGALTSNWEQWDTYCEDLTKYTKLTSCDIWGTKEVDYLGLDDFSSPYQDEEVISKTPTLAQLNSEDSQSVSDSLYYPDSLFSVKQNPLP-SSFPGKKITSRAAAPVCSSKTLQAEVP-LSDCVQKASKPT-SSTQIMVKTNMYHNEKVN-FHVECKDYVKKAKVKINP-----VQQSRPLLSQIHTDAAKENTCYCG-------AVAKRQEKKGMEP---LQGHATPALPFKETQELLLSPLPQEGPGSLAAGESSSLSASTSVSDSSQKK--EEHNYSLFVS-------------DNLGEQPTKCSPEEDEEDEE-------DVDDEDHDEGFGSEHELSENEEEEEEE--EDYEDDKDDDISDTFSEPGYENDSVEDLKEVTSISSRKRGKRRYFWEYSEQLTPSQQERMLRPSEWNRDTLPSNMYQKNGLHHGKYAVKKSRRTDVEDLTPNPKKLLQIGNELRKLNKVISDLTPVSELPLTARPRSRKEKNKLASRACRLKKKAQYEANKVKLWGLNTEYDNLLFVINSIKQEIVNRVQNPRDERGPNMGQKLEILIKDTLGLP-VAGQTSEFVNQVLEKTAEGNPTGGLVGLRIPTSKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CDG5-1", "uniprot_id": "CRERF_MOUSE", "id": "Q8CDG5-1", "name": "CREB3 regulatory factor", "aln": "------------------------------------MPQPSVSGMDPPFGDAFRSHTFSEQTLMSTDLLANSSDPDFMYELDREMNYQQNPRDNFLSLEDCKDIENLETFTDVLDNEDALTSNWEQWDTYCEDLTKYTKLTSCDIWGTKEVDYLGLDDFSSPYQDEEVISKTPTLAQLNSEDSQSVSDSLYYPDSLFSVKQNPLPPSSFPSKKITNRAAAPVCSSKTLQAEVP-SSDCVQKASKPT-SSTQIMVKTNMYHNEKVN-FHVECKDYVKKAKVKINP-----VQQGRPLLSQVHIDAAKENTCYCG-------AVAKRQERRGVEP---HQGRGTPALPFKETQELLLSPLTQDSPGLVATAESGSLSASTSVSDSSQKK--EEHNYSLFVS-------------DNMREQPTKYSPEDDEDDED-------EFDDEDHDEGFGSEHELSENEEEEEEE--EDYEDDRDDDISDTFSEPGYENDSVEDLKEMTSISSRKRGKRRYFWEYSEQLTPSQQERILRPSEWNRDTLPSNMYQKNGLHHGKYAVKKSRRTDVEDLTPNPKKLLQIGNELRKLNKVISDLTPVSELPLTARPRSRKEKNKLASRACRLKKKAQYEANKVKLWGLNTEYDNLLFVINSIKQDIVNRVQNPREEREPSMGQKLEILIKDTLGLP-VAGQTSEFVNQVLGKTAEGNPTGGLVGLRIPASKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IJW4-1", "uniprot_id": "A0A0R4IJW4_DANRE", "id": "A0A0R4IJW4-1", "name": "", "aln": "MFKTKLPPEIDDKIGRLRQRRCQKSFRQGTEDLCSAMPQPSISGMDPPFGDAFQNCSFADQALTSTDLLANSSDPDFMYELDRDMTCRQSPRGDIFTVGDCKDLDTMDHLPELVDSDPACNSNFEQWDTYWEDLTKYTRLTSCDIWGTKEVDFLGLDDFSSPYQDEEVISRTPTLAQLNSEDSQPVCDTLYHPDLLVGQKQLLFPTPTMAKK--TNRFSNPSTGASSSRNPLPDFAEGSQKATWPVPSSTDTMAKAQIHGPSKTSTELLENTDYVRKAKVCFSVPRKPLVESSAQPVSISSSTPIQESTASLVSEDPAVITAANTASSISCEKRVAIPKREVTSGPAPEVGTLRAVPHKLHFPSATGSETLLTMSALGSDASAADKKKEEEHNYSLFLTRARLAGKVTADIEEEEEEEEEEVDDEEEEEEEEEEKAEELDLDDEDHDEGFGSEHELSENDEEEEEEDDEDYEGDKDDYASDAFSEPGCDTDMVDDVKGLTAGISRKRGKRRYFWEYSEQIIPFKQERMLKPSEWDRDTLPSNMYQKNGLHHGKYTLKKSRRTDVEDLTPNPRKLLQIGNELRKLNKVISDLTPVSELPLTARPRSRKEKNKLASRACRLKKKAQYEANKVKLWGLGTEYDRLLFVINAIKEEIVNKVQDISQDKTTSMTEKLDKLIEDTLVEPPVASQTSDFVNQILENTGKGDPTGGLVGLRVPTSKV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *****:***********:. :*::*:* *******************:*. :*.**.::::: ****::.:: :.:::*.: * .**:****** *******:*************:*****************:*************.*.*:**:** *.. ** :* .::. * *.* : * .:.: : :* :: ***: *. ***: *.*:::: .*.. :* .***:**** :. *:.. :* . :*.*. :.*: . . * : ..: * *. * * . *. .: ::** * :.:::** ********:: :: *: : . *::*::*: :.******************:****** ****.*:** **:***** :.* *:*:* :*: ****************: * :***:*:****:*******************::***************:***************************************************************.****.******:**::***:**: ::: ..* :**: **:*** * **.***:****:* :*.:*:*********:*:***", "identical_positions": 383, "similar_positions": 156, "identity": "53.27%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120203-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LZ52-1", "uniprot_id": "KLHL3_RAT", "id": "F1LZ52-1", "name": "Kelch-like protein 3", "aln": "-----------------------------------------------------------------------------------------------------------MEGESVKPSPQPTEQAGDGEKNRRMITVNPAHMGKAFKVMNELR--SKRLLCDVMIVAEDVEVEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAY-AEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLDHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEGRWDQIAELPSRRCRAGVVFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWIYVADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPVTDKWTLLPTNMSTGRSYAGQWVSASGA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E0CZ16-1", "uniprot_id": "KLHL3_MOUSE", "id": "E0CZ16-1", "name": "Kelch-like protein 3", "aln": "-----------------------------------------------------------------------------------------------------------MEGESVKPSPQPTAQAEDEEKNRRTVTVNAAHMGKAFKVMNELR--SKRLLCDVMIVAEDVEVEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAY-AEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLDHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEGRWDQIAELPSRRCRAGVVFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWIYVADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPVTDKWTLLPTNMSTGRSYAGVAVIHKSL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UH77-1", "uniprot_id": "KLHL3_HUMAN", "id": "Q9UH77-1", "name": "Kelch-like protein 3", "aln": "-----------------------------------------------------------------------------------------------------------MEGESVKLSSQTLIQAGDDEKNQRTITVNPAHMGKAFKVMNELR--SKQLLCDVMIVAEDVEIEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAY-AEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLEHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEDRWDQIAELPSRRCRAGVVFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWIYVADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPVTDKWTLLPTNMSTGRSYAGVAVIHKSL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F6F9-1", "uniprot_id": "KLHL3_DANRE", "id": "E7F6F9-1", "name": "Kelch-like protein 3", "aln": "------------------------------------------------------------------------------------------------MVLWGFFLRFRFFLTCGRNCIQKTLDSQDDAKDPGLHTFSHTHMRKAFLLMNDLRSHSRKMLCDVLLVAGEVEIPAHRVVLASCSPYFCAMFTGDMSESKANHVEIRDVDGQTLLKLVDYIYSAEIEVSEENVQVLLPAASLLQLMDVRQVCCDFLQTQLHPTNCLGIRAFADLHACTVLLSQAHAYAAEQHFTDVMVGEEFMALSLQQVCSLISSDKLTVSTEEKVFEAMVAWIKHDKEARLEHMPKLMEHVRLPLLSRDYLVQIVEEEPLIKNNNTCKDFLIEAMKYHLLPADQRHLIKTDRTRPRTPISLPKVMMVVGGQAPKAIRSVECYDFQEDRWYQVADLPSRRCRAGVVYMAGKVYAVGGFNGSLRVRTVDVYDGLKDQWSSIPSMQERRSTLGAAVLGDLLYAVGGFDGSTGLSSVEAYNPKANEWMFVAPMNTRRSSVGVGVVDGKLYAVGGYDGASRQCLSTVEEFNPVSNKWCYVSDMSTRRSGAGVGVLSGQLYAAGGHDGPLVRKSVEVYDPTTNTWRQVCDMNMCRRNAGVCAINGLLYVIGGDDGSCNLSSVEYYDPAADKWSLIPTNMSNGRSYAGVSVIDKPL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04652-1", "uniprot_id": "KELC_DROME", "id": "Q04652-1", "name": "Ring canal kelch protein", "aln": "MIALSALLTKYTIGIMSNLSNGNSNNNNQQQQQQQQGQNPQQPAQNEGGAGAEFVAPPPGLGAAVGVAAMQQRNRLLQQQQQQHHHHQNPAAEGSGLERGSCLLRYASQNSLDESSQKHVQRPNGKERGTVGQYSNEQHTARSFDAMNEMR--KQKQLCDVILVADDVEIHAHRMVLASCSPYFYAMFT-SFEESRQARITLQSVDARALELLIDYVYTATVEVNEDNVQVLLTAANLLQLTDVRDACCDFLQTQLDASNCLGIREFADIHACVELLNYAETY-IEQHFNEVIQFDEFLNLSHEQVISLIGNDRISVPNEERVYECVIAWLRYDVPMREQFTSLLMEHVRLPFLSKEYITQRVDKEILLEGNIVCKNLIIEALTYHLLPTET----KSARTVPRKPVGMPKILLVIGGQAPKAIRSVEWYDLREEKWYQAAEMPNRRCRSGLSVLGDKVYAVGGFNGSLRVRTVDVYDPATDQWANCSNMEARRSTLGVAVLNGCIYAVGGFDGTTGLSSAEMYDPKTDIWRFIASMSTRRSSVGVGVVHGLLYAVGGYDGFTRQCLSSVERYNPDTDTWVNVAEMSSRRSGAGVGVLNNILYAVGGHDGPMVRRSVEAYDCETNSWRSVADMSYCRRNAGVVAHDGLLYVVGGDDGTSNLASVEVYCPDSDSWRILPALMTIGRSYAGVCMIDKPMXMEEQGALARQAASLAIALLDDENSQAEGTMEGAIGGAIYGNLAPAGGAAAAAAPAAPAQAPQPNHPHYENIYAPIGQPSNNNNNSGSNSNQAAAIANANAPANAEEIQQQQQPAPTEPNANNNPQPPTAAAPAPSQQQQQQQAQPQQPQRILPMNNYRNDLYDRSAAGGVCSAYDVPRAVRSGLGYRRNFRIDMQNGNRCGSGLRCTPLYTNSRSNCQRQRSFDDTESTDGYNLPYAGAGTMRYENIYEQIRDEPLYRTSAANRVPLYTRLDVLGHGIGRIERHLSSSCGNIDHYNLGGHYAVLGHSHFGTVGHIRLNANGSGVAAPGVAGTGTCNVPNCQGYMTAAGSTVPVEYANVKVPVKNSASSFFSCLHGENSQSMTNIYKTSGTAAAMAAHNSPLTPNVSMERASRSASAGAAGSAAAAVEEHSAADSIPSSSNINANRTTGAIPKVKTANKPAKESGGSSTAASPILDKTTSTGSGKSVTLAKKTSTAAARSSSSGDTNGNGTLNRISKSSLQWLLVNKWLPLWIGQGPDCKVIDFNFMFSRDCVSCDTASVASQMSNPYGTPRLSGLPQDMVRFQSSCAGACAAAGAASTIRRDANASARPLHSTLSRLRNGEKRNPNRVAGNYQYEDPSYENVHVQWQNGFEFGRSRDYDPNSTYHQQRPLLQRARSESPTFSNQQRRLQRQGAQAQQQSQQPKPPGSPDPYKNYKLNADNNTFKPKPIAADELEGAVGGAVAEIALPEVDIEVVDPVSLSDNETETTSSQNNLPSTTNSNNLNEHND", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : . . :. . * ::* **::* .:: ****::** :**: ***:***:***** **** .:.**: :: ::.**.::* *:**:*:* :**.*:******.**.**** ***: ******:**..:****** ***:*:*. **. *.:* **** :*: :**: ** :** ***..*:::*..**:*:*.:::*:.:: * :. . ********:*.::*:.* *::* *::.* .**:::***:.***** : *. ** **.*:.:**:::*:************ **:.* :* * *::*.****:*: :..:******************** .***:. ..*: ******.***.. :********:***:*.* *. *:: * *:*.*.***********.* ********* :*****:**.:** :: * *::**:**********.. ***.******:**:***.** **:*:.*.**. ******* * :*****:*****:.**:*** * * :*.* ::*: *: ****** : . ", "identical_positions": 312, "similar_positions": 169, "identity": "21.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120203-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88452-1", "uniprot_id": "STC2_MOUSE", "id": "O88452-1", "name": "Stanniocalcin-2", "aln": "-------------------MCAERLGQFVTLALVFATLDPAQGTDSTNPPEGPQDRSS-QQKGRLSLQNTAEIQHCLVNAGDVGCGVFECFENNSCEIQGLHGICMTFLHNAGKFDAQGKSFIKDALRCKAHALRHKFGCISRKCPAIREMVFQLQRECYLKHDLCSAAQENVGVIVEMIHFKDLLLHEPYVDLVNLLLTCGEDVKEAVTRSVQAQCEQSWGGLCSILSFCTSNIQRPPTAAPEHQPLADRAQLSRPHHRDTDHHLT------ANRGAKGERGSKSHPNAHARGRTGGQSAQGPSGSSEWEDEQSEYSDIRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O76061-1", "uniprot_id": "STC2_HUMAN", "id": "O76061-1", "name": "Stanniocalcin-2", "aln": "-------------------MCAERLGQFMTLALVLATFDPARGTDATNPPEGPQDRSS-QQKGRLSLQNTAEIQHCLVNAGDVGCGVFECFENNSCEIRGLHGICMTFLHNAGKFDAQGKSFIKDALKCKAHALRHRFGCISRKCPAIREMVSQLQRECYLKHDLCAAAQENTRVIVEMIHFKDLLLHEPYVDLVNLLLTCGEEVKEAITHSVQVQCEQNWGSLCSILSFCTSAIQKPPTAPPERQPQVDRTKLSRAHHGEAGHHLPEPSSRETGRGAKGERGSKSHPNAHARGRVGGLGAQGPSGSSEWEDEQSEYSDIRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB40E9D1-1", "uniprot_id": "A0AB40E9D1_DANRE", "id": "A0AB40E9D1-1", "name": "Stanniocalcin", "aln": "MLQWSGSPRQRYIQQRSSPSRDMRAQLTLGVFILFLAVRQTHTTESASAHDTSQEKSLNIHKKRLSLQNTAEIQQCLVNAGDVGCGMFECFNNNSCEIRGLHDICMTFLHNAGKFDSQGKSFIKDTLKCMAHGLRHKFSCVSRKCVAVKEMVFQLQRECYLKHNLCLAVRENVNVMVEMIHFKDLFPKGPHVELVNILLGCGEEVRVAIGRRIRTQCEQNWGALCGTLSLCALGKVEN-QASSTLAPVPDVTTTPGANT-NALHPTS-----FPHPEADGQAVWTLTETREEENLSSG--PQDNSSDAQKELKRSPNATKRR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : ::: :. :: *:::.. : .*::* :* ***********:***********:****:******:***.*************:********:*:* **.***:*.*:**** *::*** **********:** *.:**. *:*********: : *:*:***:** ***:*: *: : ::.****.**.**. **:*: . *.. * * : . .: :: * . . *.*: . . . .. .* .*. *..:: * ::* : **", "identical_positions": 139, "similar_positions": 83, "identity": "43.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120203-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q12981-4", "uniprot_id": "SEC20_HUMAN", "id": "Q12981-4", "name": "Vesicle transport protein SEC20", "aln": "----MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSALTELNTKVKEKFQQLRHRIQDLEQLAKEQDKESEKQLLLQEVENHKKQMLSNQASWRKANLTCKIAIDNLEKAELLQGGDLLRQRKTTKESLAQTSSTITESLMGISRMMAQQVQQSEEAMQSLVTSSRTILDANEEFKSMSGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6QD59-1", "uniprot_id": "SEC20_MOUSE", "id": "Q6QD59-1", "name": "Vesicle transport protein SEC20", "aln": "----MAAPQDVHVRICNQEIVKFDLEVKALIQDIRDCSGPLSELTELNTKVKEKFQQLKQRIQELEQSAREQDKESEKQLLLQEVENHKKQMLSNQTSWRKANLTCKLAIDNLEKAELLQGGDSLRQRKTTKESLAQTSSSITESLMGISRMMSQQVQQSEEAMQTLVSSSRTLLDANEEFKSMSGTIQLGRKLITKYNRRELTDKLLIFLALALFLATVLYIVKKRLFPFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IG59-1", "uniprot_id": "A0A0R4IG59_DANRE", "id": "A0A0R4IG59-1", "name": "", "aln": "MTTNMASSSDVHVRICGQEIIKYDLEIKAIIQDIRECCGPQAVLMELNSTVKEKFSLLRQRIQDMEQMAKEQDRETDKQALLSETEGHRKQMLSNQMAWRKANLACKLAIDNLEKDELLQGGDAVRQRKATKESLVQTSSDITESLMSISRMMSQQVQQSDETIGTLVTSSRTVQETNEEFKAMTGTIHLGRKLILKYNRRELTDKLLIFLAIALFLATVLYILKKRLFPFI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:..*******.***:*:***:**:*****:*.** : * ***:.*****. *::***::** *:***:*::** **.*.*.*:******* :******:**:******* ******* :****:*****.**** ******.*****:******:*:: :**:****: ::*****:*:***:****** ****************:**********:*******:", "identical_positions": 167, "similar_positions": 48, "identity": "71.98%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120206-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60245-1", "uniprot_id": "PCDH7_HUMAN", "id": "O60245-1", "name": "Protocadherin-7", "aln": "MLRMRTAGWARGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVT---GSGEVTFSLESGSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGD----------QNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEEN------------NNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPS--YEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKD-HEDFFTPQ---------QHDKSKKPKKDKKNK---KSKQPLYSSIVTVEASKPNGQRYDSVNEKLSDSPS--MGRYRSVNGG------------PGSPDLARHYKSSSPLPTVQLHPQSP-TAGKKHQAVQDLPPANTFVGAG----DNISIGSDHCSEYSCQTNNKYSKQMRLHPYITVFG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QAA1-1", "uniprot_id": "F1QAA1_DANRE", "id": "F1QAA1-1", "name": "", "aln": "-MGSRSVGAVHSARCYLVLILQLLTQLPHADSALRYRVAEEGPADVHIGNVASDLGLSTSGIGTGDVTFALESGSEFFKIDNVTGELTTGSRRIDREKLPQCQMIFDENECFLNFEVSVIGPLQSWVDLFDGRIVVTDINDNTPSFPSPVLTLSVEENRPIGTLYLLPTATDRDFGRNGIDRYELIQDSRDGGSS--SRRP------------ANGPTNG-NGGDRRRGPET----GTGPASRSSVFELQVADTPEGQKQPQLIVKGPLDREARDSYELVLRVRDGGNPPRSSQALLRVSITDVNDNSPRFERAVYEAEMAENAPPGTPVLQVRATDRDVGVNGQVEYVFGAATESVRRLLRLDEASGWLSVLHRIDREEVSQLRFTITARDRGQPPRTDRTTVVLNVRDENDNVPIVEIRKIGRILVRDGAAMVPENVLVDTPVALVQVSDRDQGENGAVTCTVVGDVPFTLKPAGETALAPPPATDDAFERNKKKYFLHTSALLDYEATREYSVTIVAVDSGSPSLSSNSSLLVRVVDINDHAPTFAQSLVEVHFAENNAPGERVVTVVAADADSGKNAEIAYSLDPSVNGAFYIDADNGDIRATGALDRELRERYEFRVIARDKGTPSLQGSATVVVQVTDRNDNAPKFVQEVFTFYVKENLLTNSPVGMVTVTDADEGENAELSLFVEHDEEEGGEEGKEGKQEVFSIENNTGTIFSSASFDRERRSTYSFRVRAVDGGEPPRSATATVSLFVTDENDNAPSITSPANESYTLLPPASGARTVVRTVSASDGDTGSNADLRYALVGGNPFRLFEIGSSSGVITLAEPLERRHRGLHRLVVRVNDSGMPSLCATALVHVFINESLANATLVDAQVARSLAIPLYMDIAGDPDSERALGKQRLSVAIGVLAGAAAVILVILLVVTARQCGAQGKNGYEAGKKEPEEDFFGPQPPPLQAQGSQNERGRKPRRDKRNNGTAKSERSLYSGIMTVNGCRRGGGDEEEEDEESSSASERIAARYCAAANGDPSSPRLGSRRHQSSPDLARHYKSSSPLPAVHLQPNSPPVEGKKHQAVQELPPTNTFTGNGTGNADAMSLSSDQCSDYGCQT-IKYSKQPLRRVTFSVVSQAPDQGCYDSGVEDSETPSSKSSSGPRLGSLPLPEDGYERTTPEGSVGEEEHVENDSRQLPDVALTGKCTHECNEYGHSDTCWMPVQSSPRRRIEPPQLSTFASPGDNNNNTEDNSDREEDGDGGTDKSSGGSDEVRDSLANGDPLGTLSRRDRNRNMGDHNRNLLNRKMTSASYDTFSSAGFGRRPDEEDSHPPEVIPLTRTGADYKTTSCLTLSRREVYL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 723, "similar_positions": 229, "identity": "53.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120206-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GLX4-1", "uniprot_id": "A0A8I6GLX4_RAT", "id": "A0A8I6GLX4-1", "name": "Disks large homolog 5", "aln": "MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAGG--AKAELLLQLLLAKE---QDHFQDLRAALEKTQPHLLPILYLNGVVGPPQSTEGAGSTYSVLSIMPSDSESSSSLSSVGTTGKAPSPPPLLTEQQANDKVENLSIQLRLMTRERNELRKRLAFATHGATFDK---------RPYHRLNPDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTQLKDDVDMLRRENGKLRRERNLLQQSWEDMKRLREEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKLEVVKKDYDALRKRYSEKVAMHNSDLSRLEQLGEENQRLQKQTEMLTQQRDTAIQLQHQCALSLRRFETIHHELSKATAQNKDLQWEMELLQSELTELRSKQVKTAKESEKYKEERDAVYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSEKKAASEEVEALR-----------------------------------------------------------------------------QIKDTVTMDAGRANKEVEVLRKQCKALCQELKEALQEADVAKCRRDWAFRERDKIVAERDSIRTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMECQLEKEARFRQLMAHSSHDSAIDTDSMEWETEVVEFVRETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRVNDWLLR---INDVDLINKDKKQAIKALLNGEG-AINMVVRRRKSLGGKVVTPLHINLSGQKDSGISLENGVYAAAVVPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESLLRSCQDSLTLSLLKVFPQSSSWSGQNIFENIKDSDRMLSCRAHGPEVQAHNKRNLLQHNNSTQTDIFYTDRLEDRKELDHSGGSSSYLYKPFSGASSPASPQACPSTSERSLNSFRSDTSAERGYGLVDVQSQRPLLSFETEVGPCGTVGAPLDKIDPEGSNSGGTWPKAVLGSTSGPEKLSVYKKPKQRKSIFDPNTFKRPQTPPKVDYLLPGLGLTHSPQP---SKRADTPKGSLTPPKPPRRSDSIKFQHRLETSSESEATLVGSSPSTSPPSAPPPSMDPSEPMHASPPRKARVRIASSYHSEGDGDTSYLPVKKPCDEDLTSQKVDELGQKRRRP-KSAPSFRPKISPVVIPAQCLEEQDCAPVSGELSPEAQDWSPYTLGHASRPGNPLLYPNRPSVGTVPRSMTPSTTVSSILRNPIYTVRSHRVVPCGSPPVPRDAGSHSLSSSVQHQGRLSLDLSHR---ACSDYSEMRASQGSNSLPSSARLGSSSNLQFKAERIKIPLTPRYPRSVMGSDRGSLSHSECS-----TPPRSPLNVDALSFCSQPQTSASTLPRIAVNSSSHGERR-------------------------KDRPFVEEPRHVKVQKGSEPLGISIVSGEKGG-IYVSKVTMGSIAHQAGLEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNP-HIHQLNSHSRSSSHLDPAAAPHSTLQGSSAATPEHPSVIDPLMEQDEGPGTPP------------------------------------AKQSTPSSRIVGDASKKTPEPRI---------------VFIKKSQLDLGVQLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGNLDMRSRTLEDVYVEMMKPKDSIRLKVQYRHEEFTRVKGLSGDSFYIRALYDRLAEV-EPELSFKKDDILYVDDTLPQGMFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDN-TAKMLSAAARRSFFRRKHKHKRSGSKDSKDLLSLDTFSNDSIP----LFEDSVSLAYQRVQKVDCTSLRPVLILGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNR-HCLLDIAPHAIERLHHMHIYPIVIFIRYKSAKHIKEQRDPVYLRDKVTQRHSKEQFETAQKIDQEYSRYFTGVVQGGALSSICTQILAMVSQEQSKVLWIPACPP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q9R9-1", "uniprot_id": "DLG5_MOUSE", "id": "E9Q9R9-1", "name": "Disks large homolog 5", "aln": "MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAGG--AKAELLLQLLLAKE---QDHFQDLRAALEKTQPHLLPILYLNGVVGPPQSTEGAGSTYSVLSIMPSDSESSSSLSSVGTTGKAPSPPPLLTEQQANDTVENLSIQLRLMTRERNELRKRLAFATHGATFDK---------RPYHRLNPDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTQLKDDVDMLRRENGKLRRERNLLQQSWEDMKRLREEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKLEVVKKDYDALRKRYSEKVAMHNSDLSRLEQLGEENQRLQKQTEMLTQQRDTAIQLQHQCALSLRRFETIHHELSKATAQNKDLQWEMELLQSELTELRSKQVKTAKESEKYKEERDAVYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSEKKAASEEMEALR-----------------------------------------------------------------------------QIKDTVTMDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSIRTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMECQLEKEARFRQLMAHSSHDSAIDTDSMEWETEVVEFERETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRVNDWLLR---INDVDLINKDKKQAIKALLNGEG-AINMVVRRRKSLGGKVVTPLHINLSGQKDSGISLENGVYAAAVVPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESLLRSCQDSLTLSLLKVFPQSSSWSGQNIFENIKDSDRMLSCRAHGPEVQAHNKRNLLQHNNSTQTDIFYTDRLEDRKELGHSGGSSSFLHKPFSGSSSPVSPQACPSTSERSLNSFRSDTSAERGYGLVDMRSQRPLLSFETEVGPCGAVEVPLDKIDPEGSNSGGTWPKAVLGSTSGPEKLSVYKKPKQRKSIFDPNTFKRPQTPPKIDYLLPGPGLTHSPQP---SKR----VGSLTPPKPPRRSDSIKFQHRLETSSESEATLVGSSPSTSPPSAPPPSMDPSEPTHASPPRKARVRIASSYHSEGDGDTSYLPAKKPCDEDLTSQKVDELGQKRRRP-KSAPSFRPKISPVVIPAQCLEEQECVPAIGELSPEGQEWSPYSPGHASRHGNPLLYPNRPSVGTVPRSMTPGTTVGSILRNPIYTVRSHRVLPCGSPPVPRDAGSQSLSPSVQHQGRLSLDLSHR---ACSDYSEMRASQGSNSLPSSARLGSSSNLQFKAERIKIPLTPRYPRSVMGSDRGSLSHSECS-----TPPRSPLNIDTLSSCSQPQTTASTLPRIAVNPSSHGERR-------------------------KDRPFVEEPRHVKVQKGSEPLGISIVSGEKGG-VYVSKVTLGSIAHQAGLEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNP-HIHQLNSHSRSSSHLDPAATPHSTLQGSSAGTPEHPSVIDPLMEQDEGPGTPP------------------------------------AKQSASSTRSVGDTTKKTPDPRI---------------VFIKKSQLDLGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDMRSRTVEDVYVEMLKPKDSLRLKVQYRHEEFTRVKGLPGDSFYIRALYDRLAEV-EPELSFKKDDILYVDDTLPQGVFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDN-TAKTLSAAARRSFFRRKHKHKRSGSKDGKDLLALDTFSNDSIP----LFEDSVSLAYQRVQKVDCTSLRPVLLLGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNR-HCLLDIAPHAIERLHHMHIYPIVIFIRYKSAKHIKEQRDPVYLRDKVTQRHSKEQFETAQKIDQEYSRYFTGVVQGGALSSICTQILAMVSQEQSKVLWIPACPP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDM6-1", "uniprot_id": "DLG5_HUMAN", "id": "Q8TDM6-1", "name": "Disks large homolog 5", "aln": "MEPQRRELLAQCQQSLAQAMTEVEAVLGLLEAAGALSPGERRQLDEEAGG--AKAELLLKLLLAKE---RDHFQDLRAALEKTQPHLLPILYLNGVVGPPQPAEGAGSTYSVLSTMPSDSESSSSLSSVGTTGKAPSPPPLLTDQQVNEKVENLSIQLRLMTRERNELRKRLAFATHGTAFDK---------RPYHRLNPDYERLKIQCVRAMSDLQSLQNQHTNALKRCEEVAKETDFYHTLHSRLLSDQTRLKDDVDMLRRENGQLLRERNLLQQSWEDMKRLHEEDQKEIGDLRAQQQQVLKHNGSSEILNKLYDTAMDKLEVVKKDYDALRKRYSEKVAIHNADLSRLEQLGEENQRLLKQTEMLTQQRDTAIQLQHQCALSLRRFEAIHHELNKATAQNKDLQWEMELLQSELTELRTTQVKTAKESEKYREERDAVYSEYKLIMSERDQVISELDKLQTEVELAESKLKSSTSEKKAANEEMEALR-----------------------------------------------------------------------------QIKDTVTMDAGRANKEVEILRKQCKALCQELKEALQEADVAKCRRDWAFQERDKIVAERDSIRTLCDNLRRERDRAVSELAEALRSLDDTRKQKNDVSRELKELKEQMESQLEKEARFRQLMAHSSHDSAIDTDSMEWETEVVEFERETEDIDLKALGFDMAEGVNEPCFPGDCGIFVTKVDKGSIADGRLRVNDWLLR---INDVDLINKDKKQAIKALLNGEG-AINMVVRRRKSLGGKVVTPLHINLSGQKDSGISLENGVYAAAVLPGSPAAKEGSLAVGDRIVAINGIALDNKSLNECESLLRSCQDSLTLSLLKVFPQSSSWSGQNIFENIKDSDKMLSFRAHGPEVQAHNKRNLIQHNNSTQTDIFYTDRLEDRKEPGPPGGSSSFLHKPFPGGPLQVCPQACPSASERSLSSFRSDASGDRGFGLVDVRGRRPLLPFETEVGPCGVGEASLDKADSEGSNSGGTWPKAMLSSTAVPEKLSVYKKPKQRKSIFDPNTFKRPQTPPKIDYLLPGPGPAHSPQP---SKR----AGPLTPPKPPRRSDSIKFQHRLETSSESEATLVGSSPSTSPPSALPPDVDPGEPMHASPPRKARVRIASSYYPEGDGDSSHLPAKKSCDEDLTSQKVDELGQKRRRP-KSAPSFRPKLAPVVIPAQFLEEQKCVPASGELSPELQEWAPYSPGHSSRHSNPPLYPSRPSVGTVPRSLTPSTTVSSILRNPIYTVRSHRVGPCSSPPAARDAGPQGLHPSVQHQGRLSLDLSHR---TCSDYSEMRATHGSNSLPSSARLGSSSNLQFKAERIKIPSTPRYPRSVVGSERGSVSHSECS-----TPPQSPLNIDTLSSCSQSQTSASTLPRIAVNPASLGERR-------------------------KDRPYVEEPRHVKVQKGSEPLGISIVSGEKGG-IYVSKVTVGSIAHQAGLEYGDQLLEFNGINLRSATEQQARLIIGQQCDTITILAQYNP-HVHQLSSHSRSSSHLDPAGT-HSTLQGSGTTTPEHPSVIDPLMEQDEGPSTPP------------------------------------AKQSS--SRIAGDANKKTLEPRV---------------VFIKKSQLELGVHLCGGNLHGVFVAEVEDDSPAKGPDGLVPGDLILEYGSLDVRNKTVEEVYVEMLKPRDGVRLKVQYRPEEFTKAKGLPGDSFYIRALYDRLADV-EQELSFKKDDILYVDDTLPQGTFGSWMAWQLDENAQKIQRGQIPSKYVMDQEFSRRLSMSEVKDDNSATKTLSAAARRSFFRRKHKHKRSGSKDGKDLLALDAFSSDSIP----LFEDSVSLAYQRVQKVDCTALRPVLILGPLLDVVKEMLVNEAPGKFCRCPLEVMKASQQAIERGVKDCLFVDYKRRSGHFDVTTVASIKEITEKNR-HCLLDIAPHAIERLHHMHIYPIVIFIHYKSAKHIKEQRDPIYLRDKVTQRHSKEQFEAAQKLEQEYSRYFTGVIQGGALSSICTQILAMVNQEQNKVLWIPACPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QF19-1", "uniprot_id": "A0A8M9QF19_DANRE", "id": "A0A8M9QF19-1", "name": "", "aln": "MEAKHRELLEQWQQKFPESGTDVERLLELLAERGCLSAAERAEIRRSGGGGREKIRRLIHTLLEDQNQNQQRFQELCWALEKAQP------------GDNQQHN-TGSSCSVLSAMPSDSESSSSLSSVASS-----PPAHLEKQVLSEKLEPLLSQLRQVTRERDDLRIRLALSLPGSTFDENTAAAADARRPSVKPGHDYEHMKLQCMKAMTDLQSLQNQHNKTLKRCEEAARDADYYHTLHARVVGEQTQLRDETEAVKQKYTQLLQQHTHMQQTCDELRHTHDSDQRELQDLRMQQQQVMRENGSSDLLNKLYDSALNKLEALKKEYEALRKRYNEQTALHNADVSRLEQLEEEKRRLQKQ-------RDAALHFQQQYSGSMHRFESVQQELNKLSVHNEDLQRETERLQMENTRCKTLQLKAVKDAEKLKEERDSVLSEYRLIMSERDQVIKELEKLQSGLEAAEHKLKNTSSERRVAGEEMEALRQELNSALLDRDRAIREKNELLEKYCHEVQDKAETQKELSQACKDIEMVREERDVARKERTEAIIQRDQLLREYYQARQKQDSAALDMERVSKELEVLRKQCEAVQEELQEALQEAEVAKCRRDWAFQERDKIVAERESIRTLCDNLRRERDRAVSDLADALRNLDDLRKQKNDAVRELKELKECMDEQLEKEARFRQLMAHNSHDSAIDTDSLEWETETVEFQRSTDNMDLSALGFDISEGVSDPYLPGDYGIFVSKVDKGSIAEGRLRVNDWLLK---INDVDLANKDRQQVIKAVFSGGGGVINMLVRRRKSLGGKTVTSVHLNLAGQKDCGVGLESGVFVSSVSPGSPAAKDASVCPGDRILNINGISLDNKPLSECENLLRSCRDSVSISLLKFFPQS--VSVQSISEIQRDGE-------------RNSNTDPPPRPSRKPSSISTSSSISIRKET----YSPEHVYRPEP------YHQICLHP-KRPLT-FHPASPADN-----TQQRQRP-------------TGGTWPKIIPVAMNTSDSIPVAMATADSIPP-LSIFKTPKKRKSIFDADVFKRPETLEYVKHTH-----THSPQG---SWT-----DTPAPPDPPKRSDSFKFKHKTQGSSASDSTVTAGSP-------------PATPVQES--------------SSADADACVL-------QDGCVNNTDPIELQRGRP-KSAPAPRRNLTPLKMPYTQSFSHD------EQSPEPVDLVRFSPFRSNRHSS--AFTAGHSL-TAPRALSPYPAVTAVMRNPVYTAWSHCVKTTNSASVPSHTYTQ---VSPQHQGRWSVDLNHKRSAELFDNSRGSGAHNTHSLPSSARQGLS---QYREQRIKIPSTPRYARSVHGSDRGSLSHSDCSSPSLVTPPLSPMDSASYTSG-QSQASGSTHSRLSVSPVPIDRRRDRCVLRNRSFLKLSRSQRSWFASLRTLRPFIEEPRYVTIPKGAEPLGISIVGGDNGG-IFVSKVTEGSIAQKHHLEFGDQLLEFNGVNLRNATEQLARLIIGQQCDTITILAQYNT-HMQQLGNHSRSSSRMESSLSSHSTP-----GTPDTHSNIDTLSEQDEGTMTPP------------------------------------SKQATP----TSSPHRERAEPRQ---------------VLLRKTPVDLGMRICGGNLTGVFVEDLEDG----GAHGLQPGDLILECNSVSMKSKTAEEVYLELLKPAENIVLRVQNRPQHFRRAKDTPGDGFYIRALFDHVGDS-EQELSFKKDDILYVDDTLPRGNFGYWLAWQLDENAQKLMRGHVPSKCMMDQDSQRRYSVTDGKDESGSGKTLSAAARRSFFRRKLKHKRSTSKDGRDAPAADAISTDSMP----YLEDCVSPAYQRVLKVESTNRRPVLILGPLVEPIKDMLLREAPGKYCRCLPEGMKAQQQAIERGVKDCLFIDYKRRSGHFDVTTVASIKEITEKDC-HCLLDIAPHAIERLHAVSIYPIVIFIRYRNAKQIKEQKDPVYLRDKVSQKHSKEQFESAQRIEQDYSKYFTGVVQAGALSNTCTQIMAIVDQEQNKVLWIPDGST", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKG8-1", "uniprot_id": "Q9VKG8_DROME", "id": "Q9VKG8-1", "name": "", "aln": "-----MAKMASGDLSLTSTSSQEEESSEYVGYDNTLRPPSNSSGSTTAAN------------MSNN---------------------------------NGPSKGVSSGVGVSGISGGNGANYDILQAQYKSALLELNTLRHQHANTKRRCDELATELTLYQEHYVADRNKFTDMVEESARFK---------RLLLETQNQQSQQAQNGNSQVPPVGSGNPYYFGKTQGCDGSCSEK------LAELKKERNMVAVEREKYKKSYIELEKDRNYYRERGDENQKLKVLLSQESKNVLSLTEELNQLLSEKDNVLQEHQKMSDDLVLANKEIERLKK--DEQLARAEIKVLQLANADLKKRDLLKS-------RDSSWSKEFPSGKELE----NSKELEKLRKSLEKALSEVERSSQDAEEAKRVRDWAISQREKIVQERDSVKTLCDKMRHERDKAISDSLMAIRDSEKIKKQKDEAQKKIDLLKEQMEQQE----------------------------------------------------------------------------RQNLDSNASGSRRSFRPSSYEGEDLLEVELSGYEHTSDLGIILDDSNKRKLVCGVTSSSPACGKLKINDVICKVNNLDCQSLSKRMVLDEIRACAPRSLLLVSRTRHSKRHAYSVQLKTRDRDCPHGLQLDMGVFIAKIEQNSLAFYEPELDVGDRVLSINNKSMDSVQSIEEVMQLMNDPRSDGLNLFALKYVQDQLPPGMTTSSAQTDSIDSMQHVSSAGGGGGSGPSSATKHPSRFAEFFFRKLKFSKPGTPEDNFEQEHDDAIAALD--SVLSENSSEKSKENLFNRKKRTKKEKEASKSMGTWPRTNISHENPTGTMRGNEKKRALMSLFTAGPINVDKDDELMGEVGVPEKQPAALIQDQLPPPLPPQMSKPLAHIRGSNGGAIKTHPNRNSNPVSSGVSALFPPGPPNGMPNTSYPTHPRHSLYGVTAEEINQKPIQR--------APLMGANARVKMPSQERYGTRPHSNHRLSLNITPSGDFYQPKTSGQQAQQQVMNASSTSAGFGVGSGSMVGGTGPAAGEFPVRKQQVYDVFHPPPLPKNSSGSNMFMPLHPTRGSHPPPVGQPPDVVSLKS--QNSIESILSAKSPAISEYGMYAKRHVPQAVRHVPKYPSDSESIGSGVHGGYGGFLQSNHMPGNRHTQLFPTFGPGGRGNRRSSPLTLPSPPPQQQLQQLPAATAPHDSVGIPTDLDYHPHHHTQTNAMPHPHPHPHAPYLDYGHGLGIGPYMGVGGGVSGVGGAIYEGGTFPRKKDNQRLRIPSNPS--VASKSSSMVKNSSGSIDHHYVTSTGPVSGGSMSASSSDRAPMSLMSSSIHNSYGANIAGGNGTG-----SSIGVGGGGGGGSGRGSPMPQVHVEVLSHGGGGSGKRN---------------------SNVPADFLCPGDLRRVTIDKRDKSLGITIQCNNNGGGIFVSTVADKSTAMRAGLQVGDQLLEVCGINMRAATQEIAANVLRQCGDSFTMLVQYNPEKFPSIEYEGAHNLEPESPINHSGSPTPRNSPRPPARNSLFPLPMQPQAPSTRPGSRAPLSHQSIKDQSFTDSLENQSDISSSQDMPSSAATTTTTTASATSTVYDEEPKPSLPPPPASVPAETLRYVTLHMDKSKNLGIKLFGGNKVGIYVHDVAVGSPS-DHAGIRKGDQILEYNGVDLSGVTAEQAANEISKLTDTVTMLVQNKLHTLKQIKDEPGDSFYIRVGFDRTGELNEDDLRFVKDEVLYVDNTVFNGTFGLWRAWKLDAMGHRKECGIIPSQMKVEEELR---SGEVVDCDTGTARRGSTSARRSFFRRK-KNQRSSSRDSTEIASFSNTQLSFFPDLGLLNDDGGALSYQRVELLDSPIRRPVLIIGPLSECLMVRLTIDFSNLFKLCEVTAMDCSQEAMEEGLKENIFVDYRRRGNKFECTTVEAISNACKNDRRHCILDVSISAVERLQRLQIYPIVLLLRFKSAKQIRDIRD--FGTDKISAKAAKEMYERAMKLETDYKQYISAVIPGVSIKHMCTQIKDAVDKEQDKLLWVPVSSG", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : .:..: :: * : . * . .. . ... : .: : ..* .* . .:. . . *.: .: . . . : * :* .. * ::: :: : * . : .: : :. : * : : : *: . : :.: ::. : : : ::. :* :::. :: :: :: : .:* :: ::: : ...: : : ::. :.* :*: : *:* .*: * : .: :* : ::: * *. **:: : . .:. :**.* :. * * . : . : : : .: ** :***:* : : ***:.*.: * : : ..: .: *::* . * *: : . * : . :: : . * .: : : . :. . : ::: : :. .: . **: * :.. :. . : : *: . . : :.. : * : : * . ::. .*.:: . . : :: ..* . *:* * ...: . * * :.: .* * . .:: . :. . :::. .* : .. * . ::: * :::.* :.:. : : .:* .:. . . * . .. :. : .: . :. :. : : .. .. . . . . : . . . ::* . : . : .: * : . : ** . : :.:: ..* . .* . . ** *:.*.. :: . : *... .. .* . * ... . . . : .. * : . .: * : . : . . . .. : .. * . . : . .: . . . :.: * : . . * : .: . : * . . . . . . *: .* ..:: .: : .. . . . . :: . ..*. : * *.: * :.***:* .::** ::**.*: * * : *: ******. *:*:* **:: * :: * *::*:*.***. :. .: .. . . :.. .: * . : .* * :.. * * :. :: .. : .* .: .. :**::: *** *::* :: . . *: ** *** ..:.: . * *:. *: * : : : ** : . : : *. .**.****. :*: .: * :* * **::****:*: .* ** * **:** .:: * :**: :::: * . :. : : *::********* *::** *:*. : : . . . :* :* : :**** ::.. ****::*** : : * : .. : * *...*:*:*.*:*: :*:**:**..:*: *** :*.: ::: **:**:: *:***: : *****::::::.**:*:: :* : **:: : :** :* * ::: :*.:*::.*: . ::. **** *.:**.*:**:* . ", "identical_positions": 261, "similar_positions": 608, "identity": "12.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120207-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O60336-1", "uniprot_id": "MABP1_HUMAN", "id": "O60336-1", "name": "Mitogen-activated protein kinase-binding protein 1", "aln": "-MAVEGSTITSRIKNLLRSPSIKLRRSKAGNRREDLSSKVTLEKVLGITVSGGRGLACDPRSGLVAYPAGCVVVLFNPRKHKQHHILNSSRKTITALAFSPDGKYLVTGESGHMPAVRVWDVAEHSQVAELQEHKYGVACVAFSPSAKYIVSVGYQHDMIVNVWAWKKNIVVASNKVSSRVTAVSFSEDCSYFVTAGNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGELRNNLFTDVACGRGKKADSTFCITSSGLLCEFSDRRLLDKWVELRNIDSFTTTVAHCISVSQDYIFCGCADGTVRLFNPSNLHFLSTLPRPHALGTDIASVTEASRLFSGVANARYPDTIALTFDPTNQWLSCVYNDHSIYVWDVRDPKKVGKVYSALYHSSCVWSVEVYPEVKDSNQACLPPSSFITCSSDNTIRLWNTESSGVHGSTLHRNILSSDLIKIIYVDGNTQALLDTELPGG---DKADASLLDPRVGIRSVCVSPNGQHLASGDRMGTLRVHELQSLSEMLKVEAHDSEILCLEYSKPDTGLKLLASASRDRLIHVLDAGREYSLQQTLDEHSSSITAVKFAASDGQVRMISCGADKSIYFRTAQKSGDGVQFTRTHHVVRKTTLYDMDVEPSWKYTAIGCQDRNIRIFNISSGKQKKLFKGSQGEDGTLIKVQTDPSGIYIATSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSGDSCIFVWRLSSEMTISMRQRLAELRQRQRGGKQQGPSSPQRASGPNRHQAPSMLSPGPALSSDSDKEGEDEGT-EEELPALPVLAKSTKKALASVPSPALPRSLSHWEMSRAQESVGFLDPAPAANPGPRRRGRWVQPGVELSVRSMLDLRQLETLAPSLQDPSQDSLAIIPSGPRKHGQEALETSLTSQNEKPPRPQASQPCSYPHIIRLLSQEEGVFAQDLEPAPIEDGIVYPEPS-DNPTMDTSEFQVQAPARGTLGRVYPGSRSSEKHSPDSACSVDYSSSCLSSPEHPTEDSESTEPLSVDGISSDLEEPAEGDEEEEEEEGGMGPYGLQEGSPQTPDQEQFLKQHFETLASGAAPGAPVQVPERSESRSISSRFLLQVQTRPLREPSPSSSSLALMSRPAQVPQASGEQPRGNGANPPGAPPEVEPSSGNPSPQQAASVLLPRCRLNPDSSWAPKRVATASPFSGLQKAQSVHSLVPQERHEASLQAPSP--GALLSREIEAQDGLGSLPPADGRPSRP------------HSYQNPTTSSMAKISRSISVGENL-------------------------GLVAEPQAHAPIRVS-------PLS---------------------------KLALPSRAHLVLDIPKPLPDRPTLAAFSPVTKGRAPGEAE-----------------------KPGFPVGLG-------------------KAHSTTERWACLGEGTTPKPRTECQAHPGPSSPCAQQLPVSSLFQGPEN---------------------LQPPPPEKTPNPMECTKPGAALSQDSEPAVSLEQCEQLVAELRGSVRQAVRLYHSVAGCKMPSAEQSRIAQLLRDTFSSVRQELEAVAGAVLSSP-----------GSSPGAVGAEQTQALLEQYSELLLRAVERRMERKL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6NS57-1", "uniprot_id": "MABP1_MOUSE", "id": "Q6NS57-1", "name": "Mitogen-activated protein kinase-binding protein 1", "aln": "MMAGEGSTITSRIKNLLRSPSIKLRRSKAGNRREDLSSKVTLEKVLGVTVSGGRGLACDPRSGLVAYSAGCVVVLFNPRKHKQHHILNSSRKTITALAFSPDGKYLVTGESGHMPAVRVWDVAERSQVAELQEHKYGVACVAFSPSAKYIVSVGYQHDMIVNVWAWKKNIVVASNKVSSRVTAVSFSEDCSYFVTAGNRHIKFWYLDDSKTSKVNATVPLLGRSGLLGELRNNLFTDVACGRGEKADSTFCITSSGLLCEFSDRRLLDKWVELR------TTVAHCISVTQEYIFCGCADGTVRLFNPSNLHFLSTLPRPHALGTDIASITEASRLFSGGVNARYPDTIALTFDPTNQWLSCVYNDHSIYVWDVRDPKKVGKVYSALYHSSCVWSVEVYPEIKDSHQACLPPSSFITCSSDNTIRLWNTESSGVHGSTLHRNILSNDLIKIIYVDGNTQALLDTELPGG---DKADGSLMDPRVGIRSVCISPNGQHLASGDRMGTLRIHELQSLSEMLKVEAHDSEILCLEYSKPDTGLKLLASASRDRLIHVLDAGREYSLQQTLDEHSSSITAVKFAASDGQVRMISCGADKSIYFRTAQKSGEGVQFTRTHHVVRKTTLYDMDVEPSWKYTAIGCQDRNIRIFNISSGKQKKLFKGSQGEDGTLIKVQTDPSGIYIATSCSDKNLSIFDFSSGECVATMFGHSEIVTGMKFSNDCKHLISVSGDSCIFVWRLSSEMTISMRQRLAELRQRQRGIKQQGPTSPQRASGAKQHHAPVVPPSGPALSSDSDKEGEDEGTEEEELPALPILSKSTKKELASGSSPALLRSLSHWEMSRAQETMEYLDPAPVANTGPKRRGRWAQPGVELSVRSMLDLRQIETLAPSPRGPSQDSLAVSPAGPGKHGPQGPELSCVSQNERAPRLQTSQPCSCPHIIQLLSQEEGVFAQDLEPAPIEDGIVYPEPS-DSPTMDTSAFQVQAPTGGSLGRMYPGSRGSEKHSPDSACSVDYSSSRLSSPEHPNEDSESTEPLSVDGISSDLEEPAEGDEDEEEE-GGTGLCGLQEGGPHTPDQEQFLKQHFETLANGTAPGGPARVLERTESQSISSRFLLQVQTSPLREPSLSSSGLALTSRPDQVSQVSGEQLKGSGATPPGAPPEMEPSSGNSGPKQVAPVLLTRRHNNLDNSWASKKMAATRPLAGLQKAQSVHSLVPQD------EVPSS--RPLLFQEAETQGSLGSLPQAGGCSSQP------------HSYQNHTTSSMAKLARSISVGENP-------------------------GLATEPQAPVPIRIS-------PFN---------------------------KLALPSRAHLVLDIPKPLPDRPTLTTFSPVSKGLAHNETE-----------------------QSGPLVSLG-------------------KAHTTVEKHSCLGEGTTHKSRTECQAYPGPNHPCAQQLPVNNLLQGPES---------------------LQPLSPEKTRNPVESSRPGVALSQDSELALSLQQCEQLVAELQGNVRQAVELYRAVTSYKTPSAEQSHITRLLRDTFSSVRQELEVLAGAVLSSP-----------GGSPGAVGAEQTQALLEQYSELLLRAVERRMERRL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58HQS2-1", "uniprot_id": "A0AC58HQS2_DANRE", "id": "A0AC58HQS2-1", "name": "", "aln": "-MTVENTTIKSRIKNLLRSPSIKLRRSKAGNNKENLSNKVTLEKVLGITSAGSRALACDPHSGLIAYPAGCVVVLLNPKKNKQHHIINSSRKTITTVSFSPDGKYVVTGESGHMPAVRVWDVAERTQVAELQEHKYGVACVSFSPNSKYIVSVGYQHDMIVNVWAWKKNVVVAANKVSSKVTAVSFSDDSSYFVTAGNRHVKFWYLDHTKSSKVNATVPLSGRSGLLGELRNNFFSDVACGKGRKASSTFCITTSGLLCEFNDKRMLDKWVELRKNDSFATSMATSLSVCEDLIFCGCADGTVRAFTPTDLHFICTLPHPHSLGTDIATLTEASHLFSYKQNVRYPDAVAVSYDPSSRWLSCVYNDHSLYVWDVRDLRKVGKVYSALYHSSCVWSVEVYPESRDGEQPRLSPGSFLSCSSDNTIRLWHTD---AQNTSLSRNVISNDLQKIIYMDSNTSTLLDTDCTISSNSEKVDPQTSENRTGIRTMCVSPDGLHLASGDRNGTLRIHDLESMEEILDVQAHDSEILCLEYSKPETGLKLLATASRDRLIHILDADKEYSLLQTLDEHSSSITAVRFAANEGKVRMISCGADKSIYFRTAQKTEEGTAFTRTHHIVRKTTLYDMDIDPTRKYAVIGCQDRSIRIFNIGNGKQKKVYKGSQGEDGTVIKVQTDPSGLYVATSCSDKNISIFDFYTGECVATMFGHSEVVTGMKFTNDCRHLITVSGDSCIFVWRLSPELTINMRQRLSDLKQNSRPVQKTPPNKQHTLSARKEIHSAPVIG---TMSSDSDKDVEEEEGIEEEDEMFPHLSSGSSAGEDTGSSEEKHNSLNSHMKKQSSSSE-----HESSGSRPRRRWSRRMGSIDLKVKSMLDLRQLESFAMPLFPSKSHDAPKNPPAPKNQDLG----STISLQTLAAWMPEENGQTRPHYIQLPPQTP------------ETEVLYPEGCEDQSSLAGSEYQVKKLPHG--VRCTKVNTCPEKQSPDSACSMEYSSSRLSSPEHPGEDSEPTEPLSVDGNSSELDM--EDLDEEEEE--GLRKNDVQTPVPQTPDQEAFLKRHFANLSDLNNPASPTRVTPN-ISDSKSSKFLSQNSPSRTAFPFSSNKNSDIKTTSGVVRPLVSEVRPLMENKSPFKQQESQSSERSSCQRLIQKKRTPVMDSRRLISPVAKAAANHNSSAGMRKAQSIHNISSEVDLVQTSTRPSKEVHPQPQASERPRRSLPTVPLISPTSALPKDITTTPTKLKARSYMSPTTSSMAKISRSASMGDNLNVVEIGEDTGSSDRGSCSDSSNSRSSSQSKPTTPVTQQVSWPNTSASPFPGPYTPHAAVVPTLSAGSGNSSSKGFQVKLTGSARPLLHIDIPNPLPDKPFLSSLSPSSKSPKVAQKEPLSRNPTTTPSLAGAVQLPSGIIQPVAAVHLSPSETPDQIELSMVLVPSQTKNFTDVELQPDAEPSKEDTSEAECSPISQSSLLQSTSGAQDSGLPGHQSSLTPSSVLLRLGLSKHFFTKGLWPLSPSTSSITSFISSPPINHYHLQDTSLSVDACRLVASELQSSFKRASHLYKMLSISTDSSEEQQEMSRVLSEAFEAMRDELNCLPPYTPPPPKSPSANAVHTLANSDPTLGDDRTLALLEQYSKLLLSAVEKRMDNKI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *.:**.*********************.:*:**.*********:* :*.*.*****:***:**.*******:**:*:*****:********:::*******:******************::***************:***.:**********************:***:*****:*******:*.**********:******.:*:********* ************:*:*****:*.**.******:*******.*:*:******** *::* .:** :: *********** *.*::***:.***:**:******::****:*** *.****::*:::**:.:**********:******* :*********************** :*..*. *.*.**::**********:*: .:.::* **::*.** ****:*.**.:****: . . :*.* . : *.***::*:**:* ******* ****:*:*:*:.*:*.*:**************:*******:********:***.:**** *************:***.:*:*******************: :*. ******:**********::*: **:.******.******..*****::*********:*********:*:********:***** :************:******:***:***:*************.*:**.*****::*:*..* :: *.. : *. :. ::. : ::******: *:* *** :* *:..:. : .* .**. .::..: :.. *:** .::*.*:*******:*::* . ..... . *..* ::. * * : .. .: : ** *:* .* * ::*** . *..:: * :**: . * * . .**:*******::**** ******* ****.******** **:*: *. ::**** * .:* *:***** ***:** .*:. *..*.:* . * * **:** * .. * *... : : . * .* ..* * :.*. .. : . . * ..* * . :*::****:*.: .: ** . . ..: .* ::* . .: * :** . *******::** *:*:* . ::* : .. ::* *: **: .:*. * :***:****:* *:::** :*. : * :. * *. * .: .* . .. ...:**.. . .. : . . .. : * :. * * .*..: . : * : .: ::*:: *. :.:**:...::* .**: :: . .* **..::::* ::*.::*:**: :. . ..* ..* ::* ::* *******:*** ***:**:.::", "identical_positions": 775, "similar_positions": 407, "identity": "46.49%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120207-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WVC7-1", "uniprot_id": "AKAP6_RAT", "id": "Q9WVC7-1", "name": "A-kinase anchor protein 6", "aln": "MLTMSVTLSPLRSQGPDPMATDASPMAIN-----MTPTVEQEEGEGEEAVKAIDAEQQYGKPPPLHTAADWKIVLHLPEIETWLRMTSERVRDLTYSVQQDADSKHVDVHLVQLKDICEDISDHVEQIHALLETEFSLKLLSYSVNVIVDIHAVQLLWHQLRVSVLVLRERILQGLQDANGNYTRQTDILQAFSEETTEGRLDSLTEVDDSGQLTIKCSQDYLSLDCGITAFELSDYSPSEDLLGGLGDMTTSQAKTKSFDSWSYSEMEKEFPELIRSVGLLTVATEPVPSSCG-EANEDSSQASLSDDHKGEHGEDGAPVPGQQLDSTVGMSS-LDGTLANAAEHPSETAKQDSTSSPQLGAKKTQPGPCEITTPKRSIRDCFNYNEDSPTQPTLPKRGLFLK-ETQKNERKGSDRKGQVVDLKPELSRSTPSLVDPPDRSKLCLVLQSSYPSSPSAASQSYECLHKVGLGNLENIVRSHIKEISSSLGRLTDCHKEKLRLKKPHKTLAEVSLCRIPKQGGGSGKRSESTGSSAGPSMVSPGAPKATMRPETDSASTASGGLCHQRNRSGQLPVQSKASSSPPCSHSSESSLGSDSIKSPVPLLSKNKSQKSSPPAPCHATQNGQVVEAWYGSDEYLALPSHLKQTEVLALKLESLTKLLPQKPRGETIQDIDDWELSEMNSDSEIYPTYHIK---KKHTRLGTVSPSSSSDIASSLGESIESGPLSDILSDEDLCLPLSSVKKFTDEKSERPSSSEKNESHSATRS-ALIQKLMHDIQHQENYEAIWERIEGFVNKLDEFIQWLNEAMETTENWTPPKAETDSLRLYLETHLSFKLNVDSHCALKEAVEEEGHQLLELVVSHKAGLKDTLRMIASQWKELQRQIKRQHSWILRALDTIKAEILATDVSVEDEE-GTGSPK-AEVQLCHLETQRDAVEQMSLKLYSEQYTSGSKRKEEFANMSKAHAEGSNGLLDFDSEYQELWDWLIDMESLVMDSHDLMMSEEQQQHLYKRYSVEMSIRHLKKSELLSKVEALKKGGLSLPDDILEKVDSINEKWELLGKTLREKIQDTIAGHSGSGPRDLLSPESGSLVRQLEVRIKELKRWLRDTELFIFNSCLR---------------QEKEGTS-AEKQLQYFKSLCREIKQRRRGVASILRLCQHLLDDRDTCNLNADHQPMQLIIVNLERRWEAIVMQAVQWQTRLQKKMGKESETLNVIDPGLMDLNGMSEDALEWDETDISNKLISVHEESNDLDQDPEPMLPAVKLEETHHKDSGYEEEAGDCGGSPYTSNITAPSSPHIYQVYSLHNVELHEDSHTPFLKSSPKFTGTTQPTVLTKSLSKDSSFSSTKSLPDLLGGSGLVRPYSCHSGDLSQNSGSESGIVSEGDNEMPTNSDMSLFSMVDGSPSNPETEHPDPQMGDAANVLEQKFKDNGESIKLSSVSRASVSPVGCVNGKAGDLNSVTKHTADCLGEELQGKHDVFTFYDYSYLQGSKLKLPMIMKQPQSEKAHVEDPLLGGFYFDKKSCKAKHQASESQPDAPPHERILASAPHEMGRSAYKSSDIEKTFTGIQSARQLSLLSRSSSVESLSPGGDLFGLGIFKNGSDSLQRSTSLESWLTSYKSNEDLFSCHSSGDISVSSGSVGELSKRTLDLLNRLENIQSPSEQKIKRSVSDMTLQSSSQKMPFAGQMSLDVASSINEDSPASLTELSSSDELSLCSEDIVLHKN--KIPESNASFRKRLN-RSVADESDVNVSMIVNVSCTSACTDDEDDSDLLSSSTLTLTEEELCLKDEDDDSSIATDDEIYEESNLMSGLDYIKNELQTWIRPKLSLTREKKRSGVTDEIKVNKDGGGNEKANPSDTLDIEALLNGSIRCLSENNGNGKTPPRTHGSGTKGENKKSTYDVSKDPHVADMENGNIESTPERER-EKPQGLPEVSENLASNVKTISESELSEYEAVMDG--SEDSSVARKEFCPPNDRHPPQMGPKLQHPENQSGDCKPVQNPCPGLLSEAGVGSRQDSNGLKSLPNDAPSGARKPAGCCL-LEQNETEESASISSNASCCNCKPDVFHQKDDEDCSVHDFVKEIIDMASTALKSKSQPESEVAAPTSLTQIKEKVLEHSHRPIHLRKGDFYSYLSLSSHDSDCGEVTNYIDEKSSTPLP---PDAVD---------------------------------------------SGLDDKEDMDCFFEACVEDEPV--NEEAGLPGALPNESAIEDGAEQKSEQKTAS-----SPVLSDKTDLVPLSGLSPQKGADDAKEGDDVSHTSQGCAESTEPTTPSGKANAEGRSRMQGVSA-TPEE-NAASAKPKIQAFSLNAKQPKGKVAMRYPSPQTLTCKEKLVNFHEDRHSNMHR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9Q9K8-1", "uniprot_id": "E9Q9K8_MOUSE", "id": "E9Q9K8-1", "name": "A-kinase anchor protein 6", "aln": "MLTMSVTLSPLRSQDPDPMATDASPMAIN-----MTPTVEQEEGEGEEAVKDVGAEQQYGKPPPLHTAADWKIVLHLPEIETWLRMTSERVRDLTYSVQQDADSKHVDVHLVQLKDICEDISDHVEQIHALLETEFSLKLLSYSVNVIVDIHAVQLLWHQLRVSVLVLRERILQGLQDANGNYTRQTDILQAFSEETTEGRLDSLTEVDDSGQLTIKCSQNYLSLDCGITAFELSDYSPSEDLLGGLGDMTTSQAKTKSFDSWSYSEMEKEFPELIRSVGLLTVATEPVPSSCG-AANEDSSQVILSEDHRGGHEEDGALEPGEQLGSTLETSS-LGDTLTNAAEHPPETANQDSTSSPQLGAKKSQPGPCEMMTPKRSIRDCFNYNEDSPTQPTLPKRGLFLK-ETLKNERRGSDGKGRVVDLKPELSRSTPSLVEPPDRSKLCLVLQSSYPSSPSAASQSYECLHKVGIGNLENIVRSHIKEISSSLGRLTDCHKEKPRLKKPHKTLAEVSLCKIPKRGTGSGKQSENTRSSVVPTMVSPGAPKATARPATDSASTTSGDTCHQRNRGGKLPAQSKASSSSPCSHSSESSLGSDNIKSPLPLLSK--SQKGSPPAPCHATQNGQVVEAWYGSDEYLALPSHLKQTEVLALKLENLTKLLPQKPRGETIQDIDDWELSEMNSDSEIYPTYHIK---KKHTRLGTVSPSSSSDIASSLGESIESGPLSDILSDEDLCMPLSGMKKFTDEKSERPSSSEKNESHSATKS-ALIQKLMKDIQHQDNYEAIWERIEGFVNKLDEFIQWLNEAMETTENWTPPKAETDSLRLYLETHLSFKLNVDSHCALKEAVEEEGHQLLELIASHKAGLKDMLKMIASQWKELQRQIKRQHSWILRALDTIKAEILATDVSVEDEE-GTGSPK-AEAQLCYLEAQRDAVEQMSLKLYSEQYTSGSKRKEEFADMSKAHSVGSNGLLDFDSEYQELWDWLIDMESLVMDSHDLMMSEEQQQHLYKRYSVEMSIRHLKKTELLSKVEALKKGGLSLPNDILEKVDSINEKWELLGKTLREKIQDTMAGHSGSGPRDLLSPESGSLVRQLEVRIKELKRWLRDTELFIFNSCLR---------------QEKEGTS-AEKQLQYFKSLCHEIKQRRRGVASILRLCQHLLDDRDTCNLNADHQPMQLIIVNLERRWEAIVMQAVQWQTRLRKKMGKESETLNVIDPGLMDLNGMSEDALEWDETDISNKLISVHEESNDLDQDLEPMVPTVKLEETHHKDSGYEEEAGDCGGSQYTSNITAPSSPHIYQVYSLHNVEFHEDSHTQFLKSSPKFTGTVQPTVLTKSLSKDSSFSSTKSLPDLLGGSSLVRPYSCQSGDLSQNSGSESGIVSEGDNEMPTNSDMSLFSMVDGSPSNPETQHLDPQMGDAANVLEQKFKDEGECIKLSSVSQASVSPVGCVNGKAGDLNSITKHTTDCLGDELQGKHEVFTFYDYSYLQGSKLKFPMIMKQPQSEKAHLEDPLLRGFYFDKKSCKPKHQTSESQPDAPLHEKILASAPHEMGRSSYKSSDIEKALTGIQNARQLSLLSRSSSVESLSPGGDLFGLGIFKNGSDSLQRSTSLESWLTSYKSNEDLFSCHSSGDISVSSGSVGELSKRTLDLLNRLENIQSPSEQKIKRSVSDITLQSSSQKMSFSGQMSLDVASSINEDSPASLTELSSSDELSLCSEDIVLHKN--KVPESNASFRKRLN-RSVADESDVNVSMIVNVSCTSACTDDEDDSDLLSSSTLTLTEEELCLKDEDDDSSIATDDEIYEESNLMSGLDYIKNELQTWIRPKLSLSREKKRPSVTDEIKVNKDGGSTERANPSDTLDIEALLNCSIKRLSENNGNGKNPPRTHDLGTKGENKKNTYDVTKDPHVADMENGNVESTPEREK-EKPE-IPEASANLASNVKKISESKHDEYEALMDG--SDDSSVTGKEFGPPNDRHPPQIGADPQHPER--GDCTSVQNSCSGLLLETGGGSRQDSDGLKSLSNDAPSVARNAAGCCL-LEQNETEESASISSSTSCCNCKPDVFHQKDDEDCSVHDFVKEIIDMASTALKSKSQPESEVAAPTSLTQIKEKVLEHSHRPIHLRKGDFYSYLSLSSHDSDCGEVTNYIDEKSNTPLP---PDTVD---------------------------------------------SGLDDKEDVDCFFEACVEDEPA--DEEARLSSALPNESEVQDEAAK-PEQMTAS-----SSVFRDETDTVPLSGLSPQKGADDAKEGDGASHTSQGCVESAEPTTPPGKAKREGSSRKQSVSG-TPEE-NAASAKPKIQAFSLNAKQPKGKAAL-YPSPQTLTCKEKLVSFHEDRHSNMHR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13023-1", "uniprot_id": "AKAP6_HUMAN", "id": "Q13023-1", "name": "A-kinase anchor protein 6", "aln": "MLTMSVTLSPLRSQDLDPMATDASPMAIN-----MTPTVEQ--GEGEEAMKDMDSDQQYEKPPPLHTGADWKIVLHLPEIETWLRMTSERVRDLTYSVQQDSDSKHVDVHLVQLKDICEDISDHVEQIHALLETEFSLKLLSYSVNVIVDIHAVQLLWHQLRVSVLVLRERILQGLQDANGNYTRQTDILQAFSEETKEGRLDSLTEVDDSGQLTIKCSQNYLSLDCGITAFELSDYSPSEDLLSGLGDMTSSQVKTKPFDSWSYSEMEKEFPELIRSVGLLTVAADSISTNGSEAVTEEVSQVSLSVDDKGGCEEDNASAVEEQPGLTLGVSSSSGEALTNAAQPSSETVQQESSSSSHHDAKNQQPVPCENATPKRTIRDCFNYNEDSPTQPTLPKRGLFLKEETFKNDLKGNGGKRQMVDLKPEMSRSTPSLVDPPDRSKLCLVLQSSYPNSPSAASQSYECLHKVGNGNLENTVKFHIKEISSSLGRLNDCYKEKSRLKKPHKTSEEVPPCRTPKRGTGSGKQAKNTKSSAVPNGELSYTSKAIEGPQTNSASTSSLEPCNQRSWNAKLQLQSETSSSPAFTQSSESSVGSDNIMSPVPLLSKHKSKKGQASSPSHVTRNGEVVEAWYGSDEYLALPSHLKQTEVLALKLENLTKLLPQKPRGETIQNIDDWELSEMNSDSEIYPTYHVK---KKHTRLGRVSPSSSSDIASSLGESIESGPLSDILSDEESSMPLAGMKKYADEKSERASSSEKNESHSATKS-ALIQKLMQDIQHQDNYEAIWEKIEGFVNKLDEFIQWLNEAMETTENWTPPKAEMDDLKLYLETHLSFKLNVDSHCALKEAVEEEGHQLLELIASHKAGLKDMLRMIASQWKELQRQIKRQHSWILRALDTIKAEILATDVSVEDEE-GTGSPK-AEVQLCYLEAQRDAVEQMSLKLYSEQYTSSSKRKEEFADMSKVHSVGSNGLLDFDSEYQELWDWLIDMESLVMDSHDLMMSEEQQQHLYKRYSVEMSIRHLKKTELLSKVEALKKGGVLLPNDLLEKVDSINEKWELLGKTLGEKIQDTMAGHSGSSPRDLLSPESGSLVRQLEVRIKELKGWLRDTELFIFNSCLR---------------QEKEGTMNTEKQLQYFKSLCREIKQRRRGVASILRLCQHLLDDRETCNLNADHQPMQLIIVNLERRWEAIVMQAVQWQTRLQKKMGKESETLNVIDPGLMDLNGMSEDALEWDEMDISNKLISLNEESNDLDQELQPVIPSLKLGETSNEDPGYDEEADNHGGSQYASNITAPSSPHIYQVYSLHNVELYEDNHMPFLKNNPKVTGMTQPNVLTKSLSKDSSFSSTKSLPDLLGGSNLVKPCACHGGDMSQNSGSESGIVSEGDTETTTNSEMCLLNAVDGSPSNLETEHLDPQMGDAVNVLKQKFTDEGESIKLPNSSQSSISPVGCVNGKVGDLNSITKHTPDCLGEELQGKHDVFTFYDYSYLQGSKLKLPMIMKQSQSEKAHVEDPLLRGFYFDKKSCKSKHQTTELQPDVPPHERILASASHEMDRISYKSGNIEKTFTGMQNAKQLSLLSHSSSIESLSPGGDLFGLGIFKNGSDSLQRSTSLESWLTSYKSNEDLFSCHSSGDISVSSGSVGELSKRTLDLLNRLENIQSPSEQKIKRSVSDITLQSSSQKMSFTGQMSLDIASSINEDSAASLTELSSSDELSLCSEDIVLHKN--KIPESNASFRKRLT-RSVADESDVNVSMIVNVSCTSACTDDEDDSDLLSSSTLTLTEEELCIKDEDDDSSIATDDEIYEDCTLMSGLDYIKNELQTWIRPKLSLTRDKKRCNVSDEMKGSKDISSSEMTNPSDTLNIETLLNGSVKRVSENNGNGKNSSHTHELGTKRENKKTIFKVNKDPYVADMENGNIEGIPERQK-GKPNVTSKVSENLGSHGKEISESEHCKCKALMDS--LDDSNTAGKEFVSQDVRHLPKKCPNHHHFENQSTASTPTEKSFSELALETRFNNRQDSDALKSS-DDAPSMAGKSAGCCLALEQNGTEENASIS-NISCCNCEPDVFHQKDAEDCSVHNFVKEIIDMASTALKSKSQPENEVAAPTSLTQIKEKVLEHSHRPIQLRKGDFYSYLSLSSHDSDCGEVTNYIEEKSSTPLP---LDTTD---------------------------------------------SGLDDKEDIECFFEACVEGDSD--GEEPCFSSAPPNESAVPSEAAMPLQATACSSEFSDSSLSADDADTVALSSPSSQERAEVGKEVNGLPQTSSGCAENLEFTPSKLDSEKE-SSGKPGESG-MPEEHNAASAKSKVQDLSLKANQPTDKAAL-HPSPKTLTCEENLLNLHEKRHRNMHR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QAQ3-1", "uniprot_id": "F1QAQ3_DANRE", "id": "F1QAQ3-1", "name": "", "aln": "---MNVVISPNASEASSPMITAVTPTLEPGPDKHDDPDVCEPSVSADGSTQKQDPYRRFQKPPPLHTGADWKVVLHLPEIETWLRTTTERVRDLTHSVQQDSSNRHVDVHLVQLKDICEDISDHVEQIHALLETEFSLKLLSYSVNIIVDIRSVQLLWHQLRVSVLVLKERLLQGLQDSNGNYTRQTDILQAFSQDHDQARLDALTEVDDSGQLTIKCSRDYFSLDCGITAYELSDYSPIEDPE-GRGPHS------------LYPELEQDFPELLQSVDLLNIAAS-------------------------RQNQLSASSTEESVTSTQKPQETISSPTEKEEEGTTDSAMQDDSN---------------FGLSKRPLHGGFRS-ELSPTQP-LPKKPMYLE-----GDGDTRFSRPSPLQYQADLSRSTPSLLDTLDRTKFWLELESVYPGS---GSQSYESLYGMNARNLQ-----------IGLKRSGQVPLER-RLSEAEHEFSKQKHLSNPKTMHSKAKQAYSDSSSPPPS---SGEDISDHEPRAMSSSPDD---------------QAPATNSLWIMNQN---------------------------ALCISNASSNLKEHWYGSDEFLALPAQLKKTEILAMKLESLTQALPQRGLQESIQDVDDWELTEVNPDWESSTDLHLLHPYKKSSRTGRFSPTSSSDVAPSLDDSIESGPLSELMSEDE------GARSTPESRARNVSSELPNVPKMMIQCTPLIKQLLADIQHQDNYDNVWTKIEGFVSKLDEFICWLRDALETTENWTPPRADIDNLRLYLETHLSFKLNVDSHSSLKDSLLEEGRQLLELITSHKSGLRDMLHMISQQWQELQRQIRRQHNWMLRTLDAIKTHILSSERSEDEAHSHHHSPKQVEVQQSHREAQKDILDQMRGKLQSQQLWSGS-RGVDFSLMSRTSS-----LSEFEAEYQELWDWLMDMESIVTDSHDLMMSEEQQHHLYKGNSVEMSMWLPKKTHLLGWSESLKRSGSELPADFDQRLSALRSKWDQLQKTLSEHMVPSVVQQS---QRELLSPDTSRMVTQLESRIKELKSWLRETELFIFNLNLRPDNAQQCESSAQDTTEEPQHEPQTSKQLQHFKALCVEVRGRRRGISSILRLCQRLLDGPEHQSSESKRQSLQLLQVNLERRWEAIIMQTLQWQSRLKRSLGRDQVPGNLIEPSLMDLHGLTEDSWEWDEMDMT-----INMETQNCEDE---ETPGSKSHLNSPKEPSSLTES-------CPTDTQCAPSSHVYQVYSLHNVELYQQ-----PQYNHKSSPAKAQQSLLKRVSMDSSFSSAESLPDILG--DLLRGKQRLLSDSARRSESESGIVSEGDTETLGNSEICLLCQSD-------------DLKVCVTLTPPIREDSHNRDRVSDEDIDRVLERANKCAEYGDSLTIVKRDQRCHGTRKK----------------------------------------------RDDCGESRKKHRKEP-VKILAKGLGLCQESGDENPSMSGDDERVTTHRKLQKEFAQLSQGSSLDSLYAVGELFPT-----SKETLTRSTSLESWLAPCKSAEDGGSKESLRDIGSTVEPTGELSRRTLELLKRLENIQSPLALKMTRSVSDVTLQSSS---LWRGSRSAGAPSSINESSAASLTELSSTEDSSVASEDLAVQMNRCIAAESNASFRKHCHSQQQADETDASISMVVNISCTSACTDDEEDSDLLSSSTLTLTEEELGIKDDD---SSVTSEEEYIEGSFALGLDYIKGEFQSWMKPR-SQIREKNEADLVDELQCG--TLSRDILSPIKTASDRQFLSRSALRLLEANTNAKNESLKHREVD--GNRRDATRNYISCFVDDMENGNVESSHIKAKDEDDELLREEGSLLTKKGEPFKASYGVDATTGIKSNMLTTTSPSSCEQLSLGSLEGQLKGELPCHNSRRPSPSLSPIDDCSGLAAHTLSRQKQ----LAAFLNDVH---ENHQEGS-----------------SDCCSHP--SFMSKEARSENVHDFVMEIIDLTSVARKTKEEP-TEVCSPTSVSQIKEKVLEHSHRLIHLRKGDFYSYLSLSSHDSDCGEVSTCTEDKSSTPILSCSPDIRDEEPLFEACTEEVYLGPPLCYSMSISKRPTRHGAKLIEPLALLKPSSGCDEYQKAHGVSEASVAGSQSECHNEAPYLNPLPCETPIDTVECFADTKMLESN---ISPVMTKIRVSCSTTNPLKEDGSLYINPKINCPLIRKTDSDERAPASQLMKQKNVGKGRRSLLEARSTHKQLPRSESSSGVAQGCRAQISGAQTDSSSAGTTRVSSRPQVKRLSGSVTSSVSKP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.*.:** *: .** * .:* * * : ..: : : .. ::: *******.****:************ *:*******:*****:..:*****************************************:****::***************:**:******:***************:: :.***:***************::*:********:******* ** * * : *.*:*::****::**.**.:*:. : .* :. * .. . . : : ..::. *:.:. .**.::. *. * ***** ***: ::*: .: : :: :.::*******::. **:*: * *:* **.* .*****.*: :. **: .* * : *: **.:..: : ** ...*:: . ** *. . : * : *:*. . *: ::.* :.. : . . ..:: * ******:****::**:**:**:***.**: ***: *:**::*****:*:*.* * . *: ** :* * .**:****:*.**.:********:::*::: . :. .:.::.. **. * .: :. .**::*: *****:**: :* :*****.****** **.:*:*********:*: *.*:****************.:**::: ***:*****:.***:**:* *:**:.**:******:***.*:**:**:**:.**::: * :: . *** .*.* .: *:*:* ::** ** *:* *.* * :*: **:. : * :*::*********:****:* ************:**** *****: **:.**. *:**:.* ** *: :::.::..**: * *** *:: ::. :* *:****::. :* *** ****** ***:******* ** :* : :.****:**:** *:: ****::*******:***. : . ::.:*.:**: **********:**::***:**::.:*::. . *:*:*.****:*::**: **** *:: :: *::: ::: * * . ::.. *: .:: ...*.*:**********:::: : . * : * * :* ******::****:** .*:: .* ::.* **********.* **::.*: * :: ...: *. : ::.. . : . .: ** ::.*: * * . : :..* .:: . :* . : *. . .. .. . *.: *:. * : :::: **:.**::** . *:** ..::* *********:. ** ** * .* **. : ..****:***:**:******** *:.*****:****** : *. * . .*****.*.********::: *:.***:.:: * .********: :. ***:*..:**:**:**********:***************** :**:* * .*.:* * : .: ******.*:*:*::*: * *:*:. .: **:: . . : .* .* . . :*. * : * * *.*. . .* *:: . .* ******:*. : : . : : . * .: : :. * . : :.. :. : * . . . * .. . . . . * .: .:* * : :*. : . .**. * .*: .. .**:** ****::*.* *:*.:* .**.:***::************ *:**********************:. ::**.**: * * ** *: :. . . **.* .. :*. .. * *: : * *.: . . :. :. : : . . . :. :. . : . .. ..: . * ... . .*: . :. ... ::.. :: : . .: : ", "identical_positions": 861, "similar_positions": 630, "identity": "35.74%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120214-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A4X5-1", "uniprot_id": "A0A8I6A4X5_RAT", "id": "A0A8I6A4X5-1", "name": "CUB and sushi domain-containing protein 3", "aln": "MKGSRKGESRAKESKPREPGTRRCAKCGRLDFILKKKMGIKSGFTFWNLVFLLTLSCVKGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPGFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSPLTLTASIGELEKHIRTAT----VANTPADVTVSSVTAVTSHRLSEEQRVQVRSLSDSGLDPNTSEDQLSPHQADTQSTSRRPRNAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSLLNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMRSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPDSPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGPIPRCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDPGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSELPSTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRVGFSFGVGDTLTFSCSLGYRLEGSSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSLQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDSEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENEMLLKEVSGSLIPDGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGQERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTVSVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRVLPSCHAPCGSRSTGSEGTVLSPNYPKNYSVDHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVFDGPTQQSPLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNDFAVGSLVLFECNPGYILHGSRAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQIVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKVGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTIRLPIGFGVHLQFVNFSTETIHDYLEVRSGSSELSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNISMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSAAFNVTSNGHEVFLQWSADHGNNKKGFRIRYI----AFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHSWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTATCQSDGTWSNHNKTPRCVVVTCPSINSFTLEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRTERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSGSETRCLAGHCGIPDLIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPVCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGIPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQASRTCQLNGHWSGSQPHCSGDTTGTCGDPGMPGHGSRQESDFRTKSTVRFACDTGYILYGSEERTCLSNGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGNLPNCTIISCGDPGIPANGLRYGDDFVVGQNVSYMCQPGYTMELNGSRVRTCTTNGTWSGVMPTCRAVTCSTPPQISNGRLEGTNFDWGFSISYICSAGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPSQGKREGKSFIYQSEVSFSCNSPFILVGSSTRLCQTDGTWSGSSPHCIEPTRTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLADLTWSGIQPECIPHSCKQPESPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPVCEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSDMELLLSGVYKSQEARLMLHIYLIKVPANASVKKMKEENWAMDGFVSAEPDGATYVFQGFIKGKDYGQFGLQRLGLNTSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80T79-3", "uniprot_id": "CSMD3_MOUSE", "id": "Q80T79-3", "name": "CUB and sushi domain-containing protein 3", "aln": "MKGSRKGESRAKESKPREPGTRRCAKCGRLDFILKKKMGIKSGFTFWNLVFLLTLSCVKGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPGFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSPLTLTASIGELEEHIRTATGAIDVASTPADVTVSSVTAVTSHRLSEEQRVQVRSLSDSGLDPNTPEDQLSPHQADTQSTSRRPRNAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSLLNEGGIKTASNLCPDPGEPENGKRFGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMRSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPDSPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGPIPRCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDPGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSELPSTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRVGFSFGVGDTLTFSCSLGYRLEGSSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSLQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDSEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENEMLLKEVSGSLIPDGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGQERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTISVNTDYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRVLPSCHAPCGSRSTGSEGTVLSPNYPKNYSVDHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVFDGPTQQSPLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNDFAVGSLVLFECNPGYILHGSRAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKVGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTIKLPIGFGVHLQFVNFSTETIHDYLEVRSGSSEISTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNISMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSAAFNVTSNGHEVFLQWSADHGNNKKGFRIRYI----AFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHSWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTATCQSDGTWSNHNKTPRCVVVTCPSINSFTLDHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRTERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSGSETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPVCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGIPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQASRTCQLNGHWSGSQPHCSGDTTGTCGDPGTPGHGSRQESDFRTKSTVRFACDTGYILYGSEERTCLSNGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCLEGYILSGPSVRQCTANGTWSGSLPNCTIISCGDPGIPANGLRYGDDFVVGQNVSYMCQPGYTIELNGSRVRTCTTNGTWSGVMPTCRAVTCSTPPQISNGRLEGTNFDWGFSISYICSAGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPSQGKREGKSFIYQSEVSFSCNSPFILVGSSTRLCQTDGTWSGSSPHCIEPTRTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPESPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPVCEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSDMELLLSGVYKSQEARLMLHIYLIKVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIKGKDYGQFGLQRLGLNTSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z407-1", "uniprot_id": "CSMD3_HUMAN", "id": "Q7Z407-1", "name": "CUB and sushi domain-containing protein 3", "aln": "MKGIRKGESRAKESKPWEPGKRRCAKCGRLDFILMKKMGIKSGFTFWNLVFLLTVSCVKGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSLRNSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYI----AFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSNMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PNP5-1", "uniprot_id": "A0A8M9PNP5_DANRE", "id": "A0A8M9PNP5-1", "name": "", "aln": "MHIDDTEGHSVRSTGFLAVFKRGCIRCGPVDS-QAKKMGIKTGVTFWNLIFFMMVTCVRGFIYTCGGTLKGRNGTIESPGFPYGYQNGANCTWVIVAEEGNRIQIVFQSFAVEEDYDFLSLYDGHPHPANFRTRLTGFQIPPPVTSTGSVFSLRLTSDFAVSAHGFKIYYEELQSSSCGNPGVPPKGILYGTRFNVGDKIRYSCVTGYVLDGHPQLTCVTNAGNAAVWDFPVPICRAEDTCGDTLRGSSGIITSPNFPSEYYNSADCTWTILADPGDTISIIFTDFQTEEKYDYLEVEGSEPPTIWLSGMNVPSPIVSNKNWLRLHFVTDSNHRYKGFSAHYQ--------------------------------------------------------------------------------------------------------VKRSVDFKSRGVKLFPGKDNSNKFSILNEGGIKQASNSCPDPGEPENGKRIGNDFSIGATAEFTCDEDHVLQGSKSITCQRVAEVFAAWTDHRPVCRVKTCGSNLQGPSGTFSSPNFPIQYESNSQCVWIITASNLNKVIQINFEDFDLELGYDTLTIGDGGEVGDPKTILQVLTGSFVPDLIVSMTHQMWLHLQSDESVGSIGFKINYKEIDKESCGDPGTPLYGMREGDGFSNGDMLRFECQFGFELIGEKTISCQNNNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCVWLILSEPGSRIHLAFNDFDLEAPYDILTVKDGEMLDSSVLGRFTGAEVPSHLTSNSNILRLEFQADHSMSGRGFNITYTTFGHNECPDPGIPLNARRFGDSFQLGSSISIICEDGFIKTQGAETITCELNGGKVMWSGPIPKCEAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGRSIKITFEKFQTELNCDFLELHDGPNLLSPLIGSFNGTQVPQFLFSSGNHLYMLFTTDNSRSNSGFKILYESVTVDAYSCLDPGIPVNGLRYGQDFSIGSTVSFGCDSGYRLSHEEPLVCEKNHWWSHPLPTCDALCGGDVRGPGGTILSPGYPEVYPSSLNCTWTVEVSHGKGVQFTFNTFHLEDHHDYLLITENGSFVQPLARLTGAELPLPINAGLYGNFKAQLRFISDFSISYEGFNITFSEYNLEPCEDPGVPHYGRRNGYSFGIGDTLTFSCNLGYRLEGAPEIICLGGGRRMWSAPLPRCVAECGSSVINNEGILLSPNYPMNYENNHECIYSIQVQAGKGINISARTFHLAQGDILKIYDGKDNAAHMLGAFTGSSMLGLTLISTSNHLWLEFYSDAEATGEGFKLVYSSFELSHCEDPGVPQFGFKVNDQGHFSGSTITYKCDPGYTLHGSGVLKCMTGERRAWDNALPSCIAECGGRFKGETSGRILSPGYPFPYDNNLRCTWMVEVDSGNIISLQFLAFDTEASHDILRVWDGPPENEMSLREVSGSLLPENVHSTLNMVSIQFETDFYISKSGFAIEFSSSVATACRDPGVPMNGSRNGDGREPGDTVTFQCDPGYELQGDVKITCIQVENRYYWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSKDCDWLIAVNSDYVLSLAFISFSIEPNYDFLYIYDGADSNSPLIGSFQDSKLPERIESSSNTMYLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNVMNGTRLGSDYKLGSTVTFYCEAGYVLQGYSTLTCIMGDDGRPGWNRGLPSCQAPCGSRSTGTDGTVLSPNFPRNYTTGQSCVYTIAVPREFVLFGQFVLFQTSLNDVVDIYDGPTQQSSLLSSLSGSHSGESLPLSTGNQITIKFSTVGPETAKGFHFVYQAVPRTSATQCSSVPEPRFGKRIGNNFAVGASVMFECNPGYTLHGSTAIHCETVPDALAQWNDTLPTCIVPCGGILTMRKGTILSPGYPEPYDNNLNCVWKVSVPEGAGIQIQVVSFATEHNWDSLDFYDGADNNAPRLGSYSGTTIPQLLNSTSNNLYLNFVSDISVSAAGFHLEYTAIGLDTCPEPQTPTYGIKIGDRYMVGDVVMFQCEQGYSLQGNAHITCMPGPVRRWNYPVPLCLAQCGGAMTEVSGVILSPGFPGNYPSGLDCTWTITLPIGFGIHVQFLNFSTEAIHDYLEIRSGPSETGTVIDRFSGPQVPESLFSTTHETSFFFHSDYSQNKPGFHITYQAYQLQSCPDPRPFRNGIVIGSDFSVGMTVSFECLPGYSLIGETSLTCLHGISRNWNNPIPRCEALCGGNITSMNGTIFSPGHPAEYPNFQDCVWSVRVPPGNGIYINFTVLSTEPIYDYITVWDGPDQSSPQIGQFSGNTALESVYSTSNQILIKFHSDFSGSGFFVLSYHAYQLRVCQPPLEVANADILMEDNELEIGDIIRYRCHPGFTLVGSEILTCRLGERLQMDGHPPSCQVQCPAHDVRFDSSGVILSPGYPDSYPNLQMCSWSINVEKGYNITLFFEFFQTEKEYDILEVFDGPTIHSQTLATLSGDLPTPFNMTTSGHQLLLRWSADHGTNKKGFSIRYVGEYQTLYCSTPDSPLHGSISSQTGGHLNSLVRWTCDRGYRLIGKSTAVCKKTPFGFYDWDAPVPACQAVSCGVPKAPVNGGVLAMDYSVGTRVTYFCSDGYRLSSKELTSAVCQPDGTWSNHNKVPRCSVVVCPSIGSFSLEHGRWRIVNGSHYEYRTKIIFTCDPGYYRLGPAYIQCMANGAWSWKNERPHCQIISCGDLATPPSGKKIGTQTSFGATAIFTCDNGYMLVGSSVRECLSSGLWSGTETRCLAGHCGLPEQIVNGQVIGENFGYRDTVVYQCVSGFRLIGSSVRICQQDHNWSGQLPICVPISCGHPGSPIYGRTIGNGFNLNDVVSFSCNMGYVMEGPSRAQCQANRQWSQPPPTCKVVNCSDPGIPANSIRQSKIEHGNFTFGTVVFYDCNPGYYLFGSPVLTCQPTGQWDKPLPECIVVDCGHPGSPPNGLLSGDKFTFGATVRYSCTGGRQLKGESSRTCQLNGHWSAPMPFCSGDSSGTCGDPGTPSHGSRDESDFRIRSKVHFSCSVGYELFGSVERMCFPNGTWSGTQPSCKPVQCGNPGTPSNGRVYRLDGTTFSHSVIYSCMDGYLLSGSTTRQCQANGTWSGTAPNCTLINCGEPGVPANGLRYGEDFTIAQNITFMCQPGYTMEAESFSTITCTGNGTWNAPVPFCKAVTCTAPPPISNGLLEGRDFEWGTSVSYSCSPGYELSFPAILTCVGNGTWSGEVPQCLPKFCGDPGTPAFGSREGRSFIYQSEVSFSCMAPYIPVGSTTRICQTDGTWSGSQPRCIEPTRTTCENPGTPRYGSLNRTFGFKVGSMVAFQCQPGHLLQGSTTRLCQADLTWSGTQPECIPHSCKQPESPPHVDVVGMDLPSYGYTLIYSCQSGFFLSGGSEHRVCRSDGTWTGKMPVCRAGSKLSEKPIKPVPGTPSPKLNVPDDVFAPNYIWKGSYNYKGRKQPMTLSITSFNTTTGRVNVTLTSSNMELLLSGVYKSQEARLMLLVYHVKASSSSTLSKIKEEHWTLDGFVSAEPDGSTYVFQGFIQGKDYGQFGLQRLGLNMSESNNSSNPPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTTPKTQYTGCSVHENNNGQAAFENPMYNTKP---EVKNVRFDPNLNTVCTMV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . .:.: .* * :** :* ******:*.*****:*:: ::**:************ ************* *********:*** ***********:**:**:**********:*********::******* *******************:*******************:******:*************:*********::*: *:* ************:**.*:*******:**.**.**:*.*******:*:******:****** ********:**************:*.**:******************:**** ** **:::******.*************:******* *** ************:*.***:*:*.:*:****:****:*******:*******:******:***************:*****:**:**:****:*** * *********:****:****************:*:**************** *******:******:***:*****:*************:******** *:***************:* **:*****************************************:* *:*:*******:*******: :*:*:****: :*.:** **************:*********************.*************:*******.********:***:*******:***** * .******* **:* **************************************:*******:****** *.**:**********:**:************.*.:*:**********.**** ******::**********:* ***:**********.**.**********:*************************.**********.**.********:*:*******.*:*******************.********::** .*********:********************************:*:** * *:.**:********. ******:.**********:*************:*. ************:***********:*********************:********:::*:******:** **** ****:***** **:*.*.***:***:***********:****:*:.*****:**** * *:********.:************ .***************:******************* **:***.***:*************************:* *:*:****:*:.:*****:*:***:************:******************:************.***********: :**********:***********************************:**** ::**:***:*********************.**************************:*******************************:******* *********:**:************************* ****:*********::*******:*:**:..:.***:****:***:*****:*****:***:::*******.*****************:******:*::*** ****************:************:****:****: *:*:***** **** **:*****::******:************* ***********************::********:*:*****************.****************:************* ********************:*******: ***:********** ***:*******::***************:*:*********::.***************.******* ******:*:**:*****:******:***.** .***.*:****:*.**********::********* ****.******************:***.**:** *:****:***:***:::******:*****:*:************:*****:***:* ********.* ****************.******:*********.*******************************: ******************* *.**:** **:*:********:* *******. ************** ** *** ***:::*:**:******************:***.*******::*.********:*:*:*:***.*:* .* :**** .:.**:*:.**:::*:******.***** ***: ::*****:** ** * *****:***:***:****:**:***:***:*:.:*:: **********:***:****.***:*: ** *********.***********:*.**.*********.*** **.****.** *:**************:**::*:*****: **** *:*:.**:***:.***:*******:*.***.*:*******:*:******* *:*****:*********** :**********:*: **********:********** .*********************** ***:************* *****:****:****:**:*:**::**********:*** *************** *:*********:************:****.** ***.***********::****** ***.:***:*:***:**:***** *.* *::***********.. *.****::******* *.****:**:** :*.*:::*..** *.** ** *:.**:*:* **.**.********.:**:*:*:****** ******::**:***.:.*** *******. ****:*.**:**:********:*:.:.**:::*******:* :. *** ****.. :* *:****.:** **** *** :*:** *:** **.********:************************* *: *.***:************ *:* ***:**:**:*******.*:*****:*:*****.**:** *.****:***:* *:*: ********** * .****** *************:*.*.:********:******:**.****:**:********.*****:*:*.****: * :*. *******.******* *********:*********::****::*****.**:.*:****************** :* :*..: :::.*:***:*::**********:********:*************** **..**** **********************************:*************************:*:. * * **************", "identical_positions": 2916, "similar_positions": 522, "identity": "78.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120214-33", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q71RI9-1", "uniprot_id": "KAT3_MOUSE", "id": "Q71RI9-1", "name": "Kynurenine--oxoglutarate transaminase 3", "aln": "MLLAQRRLISLGCRSKPIKTIYSSSKVLGLCTSAKMALKFKNAKRIEGLDSNVWVEFTKLAADPSVVNLGQGFPDISPPSYVKEELSKAAFIDNMNQYTRGFGHPALVKALSCLYGKIYQRQIDPNEEILVAVGAYGSLFNSIQGLVDPGDEVIIMVPFYDCYEPMVRMAGAVPVFIPLRSKPTDGMKWTSSDWTFDPRELESKFSSKTKAIILNTPHNPLGKVYTRQELQVIADLCVKHDTLCISDEVYEWLVYTGHTHVKIATLPGMWERTITIGSAGKTFSVTGWKLGWSIGPAHLIKHLQTVQQNSFYTCATPLQAALAEAFWIDIKRMDDPECYFNSLPKELEVKRDRMVRLLNSVGLKPIVPDGGYFIIADVSSLGADLSDMNSDEPYDYKFVKWMTKHKKLTAIPVSAFCDSKSKPHFEKLVRFCFIKKDSTLDAAEEIFRAWNSQKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6YP21-1", "uniprot_id": "KAT3_HUMAN", "id": "Q6YP21-1", "name": "Kynurenine--oxoglutarate transaminase 3", "aln": "MFLAQRSLCSLSGRAKFLKTISSS-KILGFSTSAKMSLKFTNAKRIEGLDSNVWIEFTKLAADPSVVNLGQGFPDISPPTYVKEELSKIAAIDSLNQYTRGFGHPSLVKALSYLYEKLYQKQIDSNKEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKPVYGKRWSSSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCISDEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGWSIGPNHLIKHLQTVQQNTIYTCATPLQEALAQAFWIDIKRMDDPECYFNSLPKELEVKRDRMVRLLESVGLKPIVPDGGYFIIADVSLLDPDLSDMKNNEPYDYKFVKWMTKHKKLSAIPVSAFCNSETKSQFEKFVRFCFIKKDSTLDAAEEIIKAWSVQKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IBA4-1", "uniprot_id": "A0A0R4IBA4_DANRE", "id": "A0A0R4IBA4-1", "name": "Kynurenine--oxoglutarate transaminase 3", "aln": "----------------------------------MSSIKHKNAKRIEGLDKNVWVAFTSLAADPTVVNLGRGYPDIPPPLYVKEGLAQAALVDQLNQSTRSFGHPTLVKALSKVYGKVCDRQLDPFKEILVTVGAYGSLFSTMQALVEEGDEVVIIEPFFDTYVPMVKMAGAKPVLIPLRLKSTATTGISSADWVLDQEELASKFNSKTKAIIINTPNNPIGKVFSRSELQAIADLCIKHDTLCFSDEVYEWLIYKGHEHVKIATLPGMWDRTITIGSAGKTFSVTGWKLGWSIGPEHLIKHLQTVMQNSLYTCPTPLQEAVGRGLLRDFELMGQPDCYFSSLALELEGKRNRMAAILAQTGMTPVVPEGGYFIMADVTALNQDLTHMGDDEPYDYKFVKWMIKEKKLAAIPVSAFVGEDSVKQFEKYIRFCFIKQESTLDAAEAILKKWNKD--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::*..*********.***: **.*****:*****:*:***.** **** *:: * :*.:** **.****:****** :* *: ::*:*. :****:********.::*.*:: ****::: **:* * ***:**** **:**** *.. :*:**.:* .** ***.*******:***:**:***:.*.***.*****:*:****:********:*.*: *:****:****:************************* ********* **::***.**** *:...: *:: *.:*:***.**. *** **:**. :* ..*:.*:**:*****:***: *. **:.* .:*********** *.***:******* ...: :*** :******::******* *:: *. : ", "identical_positions": 265, "similar_positions": 107, "identity": "58.24%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120214-39", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54852-1", "uniprot_id": "KCNH7_RAT", "id": "O54852-1", "name": "Voltage-gated inwardly rectifying potassium channel KCNH7", "aln": "-MPVRRGHVAPQNTFLGTIIR----------------------------KFE-----------------------GQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVMQKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEGVAMMFIINFEYVTDEDNAASPERVNPILPVKSVNRK--LFGFKFPG-LRVLTYRKQSLPQEDPDVVVIDSS----KHSDDS------VAMKHFKSPTKESCSPSEADDTKALIQPSQCSPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLTHSRSRESLCSIRRASSVHDIEGFNVHPKNIFRDRHASEDNGRNVKGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSDVKTEKKNTSPPSSDKTIIAPKVKERTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAVHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDSLGTQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVLKGFPECLQADICLHLNQTLLQNCKAFRGASKGCLRALAMKFKTTHAPPGDTLVHCGDVLTALYFLSRGSIEILKDDIVVAILGKNDIFGEMVHLYAKPGKSNADVRALTYCDLHKIQREDLLEVLDMYPEFSDHFLTNLELTFNLRHESAK-----SQSINDSEGDTCKLRRRRLSFESEGDKDFSKENSANDADDSTDTIRRYQSSKKHFEEKKSRSSSFISSIDDEQKPLFLGTVDSTPRMVKASR-HHGEEAAPPSGRIHTDKRSHSCKD--ITDTHSWEREHARAQPEECSPSGLQRAAWGISETESDLTYGEVEQRLDLLQEQLNRLESQMTTDIQAILQLLQKQTTVVPPAYSMVTAGAEYQRPILRLLRTSHPRASIKTDRSFSPSSQCPEFLDLEKSKLKSKESLSSGKRLNTASEDNLTSLLKQDSDASSELDPRQRKSYLHPIRHPSLPDSSLSTVGILGLHRHVSDPGLPGK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ER47-1", "uniprot_id": "KCNH7_MOUSE", "id": "Q9ER47-1", "name": "Voltage-gated inwardly rectifying potassium channel KCNH7", "aln": "-MPVRRGHVAPQNTFLGTIIR----------------------------KFE-----------------------GQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVMQKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEGVAMMFIINFEYVTDEENAATPERVNPILPVKTVNRK--LFGFKFPG-LRVLTYRKQSLPQEDPDVVVIDSS----KHSDDS------VAMKHFKSPTKESCSPSEADDTKALIQPSQCSPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLTHSRSRESLCSIRRASSVHDIEGFSVHPKNIFRDRHASEDNGRNVKGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSDVKTEKKNTSPPSSDKTIIAPKVKERTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDSLGTQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVLKGFPECLQADICLHLNQTLLQNCKAFRGASKGCLRALAMKFKTTHAPPGDTLVHCGDVLTALYFLSRGSIEILKDDIVVAILGKNDIFGEMVHLYAKPGKSNADVRALTYCDLHKIQREDLLEVLDMYPEFSDHFLTNLELTFNLRHESAK-----SQSVNDSEGDTGKLRRRRLSFESEGEKDFSKENSANDADDSTDTIRRYQSSKKHFEERKSRSSSFISSIDDEQKPLFLGTVDSTPRMVKATR-LHGEETMPHSGRIHTEKRSHSCRD--ITDTHSWEREPARAQPEECSPSGLQRAAWGVSETESDLTYGEVEQRLDLLQEQLNRLESQMTTDIQAILQLLQKQTTVVPPAYSMVTAGAEYQRPILRLLRTSHPRASIKTDRSFSPSSQCPEFLDLEKSKLQSKESLSSGRRLNTASEDNLTSLLKQDSDASSELDPRQRKTYLHPIRHPSLPDSSLSTVGILGLHRHVSDPGLPGK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NS40-1", "uniprot_id": "KCNH7_HUMAN", "id": "Q9NS40-1", "name": "Voltage-gated inwardly rectifying potassium channel KCNH7", "aln": "-MPVRRGHVAPQNTFLGTIIR----------------------------KFE-----------------------GQNKKFIIANARVQNCAIIYCNDGFCEMTGFSRPDVMQKPCTCDFLHGPETKRHDIAQIAQALLGSEERKVEVTYYHKNGSTFICNTHIIPVKNQEGVAMMFIINFEYVTDNENAATPERVNPILPIKTVNRK--FFGFKFPG-LRVLTYRKQSLPQEDPDVVVIDSS----KHSDDS------VAMKHFKSPTKESCSPSEADDTKALIQPSKCSPLVNISGPLDHSSPKRQWDRLYPDMLQSSSQLSHSRSRESLCSIRRASSVHDIEGFGVHPKNIFRDRHASEDNGRNVKGPFNHIKSSLLGSTSDSNLNKYSTINKIPQLTLNFSEVKTEKKNSSPPSSDKTIIAPKVKDRTHNVTEKVTQVLSLGADVLPEYKLQTPRINKFTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDREEQKRRECGYSCSPLNVVDLIVDIMFIIDILINFRTTYVNQNEEVVSDPAKIAIHYFKGWFLIDMVAAIPFDLLIFGSGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERPYLTDKIGWLDSLGQQIGKRYNDSDSSSGPSIKDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHMQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVLKGFPECLQADICLHLNQTLLQNCKAFRGASKGCLRALAMKFKTTHAPPGDTLVHCGDVLTALYFLSRGSIEILKDDIVVAILGKNDIFGEMVHLYAKPGKSNADVRALTYCDLHKIQREDLLEVLDMYPEFSDHFLTNLELTFNLRHESAKADLLRSQSMNDSEGDNCKLRRRKLSFESEGEK----ENSTNDPEDSADTIRHYQSSKRHFEEKKSRSSSFISSIDDEQKPLFSGIVDSSPGIGKASG-LDFEETVPTSGRMHIDKRSHSCKD--ITDMRSWERENAHPQPEDSSPSALQRAAWGISETESDLTYGEVEQRLDLLQEQLNRLESQMTTDIQTILQLLQKQTTVVPPAYSMVTAGSEYQRPIIQLMRTSQPEASIKTDRSFSPSSQCPEFLDLEKSKLKSKESLSSGVHLNTASEDNLTSLLKQDSDLSLELHLRQRKTYVHPIRHPSLPDSSLSTVGIVGLHRHVSDPGLPGK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JTJ6-1", "uniprot_id": "A0AC58JTJ6_DANRE", "id": "A0AC58JTJ6-1", "name": "", "aln": "MIRSRAQQLLTDTVGLKTVFKSSSYVFHYGTNINHVLKDILDTVCRLMIAFQSMVELEVHIRLNEVPKQNIFNQVNIYKRFVIANARVQNCAIIYCNDAFCEMTGFSRPDVMQKPCTCDFLHGQLTKRHAIAQVAQALMGSEERKVEITYHRKDGSDFLCATHIIPVKNQEGVVMMFILSFDYVLKEGSMDSLDRLNHTSPARQEQKKGRFFRFRLPAPLSMLGVSKQSLPQEDPDEVTIHSADQNEKHSSCSSSLSLSLSPRELHPPTGESCSPSYGNDTRALIGQSYLGSCSPISGPQDHSSPRGPWERVDP--QESLATASRRASRASMCTFRRASSTQDLEGLSTHTQRTYRDRHASE-------GPFNQIKSSLLGSTSDSNLTKYSTINKIPLITLNFSETNHDKRPSSPHSSEKTIIAPKVKDRTHNVTDKVTQVLSLGADVLPEYKLQTPRINKLTILHYSPFKAVWDWLILLLVIYTAIFTPYSAAFLLNDPEEEKRRECGYSCSPLNVVDLIVDIMFIVDILINFRTTYINANEEVVSHPAKIAVHYFKGWFFIDMVAAIPFDLLIFEGGSDETTTLIGLLKTARLLRLVRVARKLDRYSEYGAAVLMLLMCIFALIAHWLACIWYAIGNVERLYLDHTIGWLDNLGISIGKQYNISDDASGPSIRDKYVTALYFTFSSLTSVGFGNVSPNTNSEKIFSICVMLIGSLMYASIFGNVSAIIQRLYSGTARYHLQMLRVKEFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNMVLKGFPECLQADICLHLNKTLLQSCKAFRGATKGCLRALAMRFKTTHAPPGDTLVHGGDVLTALYFLARGSIEILRDDIVVAILGKNDIFGEMIHLYAKPGKANADVRALSYCDLHTINREDLLEVLDMYPEFSDYFLSNLELTFNLRDENSK--------------DTTAPQRTLYTAVS-----------DSDTED-PDVRKRRRSTDSPIRPSRSDR----ERVRDRELHTLPGKEEEEEDEEETSRPLGLGQSLPVNLNTMPDPHTKDCVENNLFQKDVCVEEWPCGNADDSAKS---QDREGGDDCESDITFGEMEQRLDLLQENLNRLEAQMTSDIQAVLQLLQRQSALGPPAYSTVAVSPEYQKPIQPVTAIQTQSPDLENAKDSRP-----------AVPIETTSDVTAATPLVTDTQWEAELGLKPAENEASAS--QQPRALQMSIRQASLPDSAPAAGHTPALHRPSSDPGLPGQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :: .:.. * *::: *: . *:*:****************.************************ **** ***:****:********:**::*:** *:* ************.****:.*:** .: . : :*:* * : ::* :* *::*. * :* ********** *.*.*: ***. * :: :.::.** ****** .:**:*** * .. **** *****: *:*: * :* : :: ** *:*::*****.:*:**:..*.:. :******* ****:**************.********* :*****:.: :*: :** **:*********:******:*************************:************************************* **:************************:**********:* ******.*****:*******:************** .**************************************************************** ** ..*****.** .***:** **.:*****:******************************************************************:**********************************************************:****.*******:*********:************** **********:*******:*****************:********:*******:*****.*:****************:**:*********.*.:* *. :* : * .*.:* .*. :: :*:. :. :* . : *.: : * :. ::: :: * . . : :::.* : : : .* . :.::.: * : * .: ***:*:**:*********:*****:***:***::*****:*::: ***** *:...***:** : . ..::. :. * :::...:::. * * :: : ** .: : :* :: .**:.*****: :: .*** *******:", "identical_positions": 755, "similar_positions": 223, "identity": "59.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-100", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UBN1-1", "uniprot_id": "CCG4_HUMAN", "id": "Q9UBN1-1", "name": "Voltage-dependent calcium channel gamma-4 subunit", "aln": "MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGP---PPRRARGDLTHSGLWRVCCIEGIYKGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFK--TKREFLKASSSSPYARMPSYRYRRRRSRSSSRSTEASPSRDVSPMGLKITGAIPMGELSMYTLSRE-PLKVTTAASYSPDQEAS-FLQVHDFFQQDLKEGFHVSMLNRRTTPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JJV4-1", "uniprot_id": "CCG4_MOUSE", "id": "Q9JJV4-1", "name": "Voltage-dependent calcium channel gamma-4 subunit", "aln": "MVRCDRGLQMLLTTAGAFAAFSLMAIAIGTDYWLYSSAHICNGTNLTMDDGP---PPRRARGDLTHSGLWRVCCIEGIYRGHCFRINHFPEDNDYDHDSSEYLLRIVRASSVFPILSTILLLLGGLCIGAGRIYSRKNNIVLSAGILFVAAGLSNIIGIIVYISSNTGDPSDKRDEDKKNHYNYGWSFYFGALSFIVAETVGVLAVNIYIEKNKELRFK--TKREFLKASSSSPYARMPSYRYRRRRSRSSSRSTEASPSRDASPVGLKITGAIPMGELSMYTLSRE-PLKVTTAASYSPDQDAG-FLQMHDFFQQDLKEGFHVSMLNRRTTPV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B7X1-1", "uniprot_id": "A0ACD6B7X1_DANRE", "id": "A0ACD6B7X1-1", "name": "", "aln": "MAWCDRRVQTVLTSLGALAAISLMSVAIGTDYWLYSRAHICNTTSNSTDETQNLLLPKKTRGDLTHSGLWKICCIEGINNGSCYWINHFS-VEDYDTENSEYILRLVRASSLFPILSTILLLLGGVCVGIGHIYSSRNNITLSAGILFVSAGLSNIIGIIVYISSNAGDPGDKKGEDKKNLYSYGWSFYSGVLSFILAETIAVLAVNIYIEKNKEVHFKHFVFNKTTPSPSSSIYTTIPSYHYKQQRSHSCSQSRDPFKNTSSVTHG-VISSSLPLVDISMYALGGEHPLLVGGQVSYNTDLEHHNFRKVHNHIPKDVKDN-----LNRRITPV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. *** :* :**: **:**:***::********** ***** *. : *: *:::**********::****** .* *: ****. :*** :.***:**:*****:*************:*:* *:*** :***.********:****************:***.**:.***** *.****** *.****:***:.*************::** . .: :.*** *: :***:*:::**:*.*:* :. . . . * *:.::*: ::***:*. * ** * .**..* : * ::*:.: :*:*:. **** ***", "identical_positions": 191, "similar_positions": 83, "identity": "57.19%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-105", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LXQ1-1", "uniprot_id": "F1LXQ1_RAT", "id": "F1LXQ1-1", "name": "", "aln": "MGRARRPPPALHRHCEGCIDRHCRVPAEPSVSCLVISCHLLCGATFHMCKESEHTLLCPLEQVPCLNSEYGCPLSMARHKLAKHLQVCPASVVCCSMEWNRWPNVDSETVLHENIMKESPSEECLDTALALQDQKVLFRSLKMVELFPETRDATEEEPAMNGDTSWEETAG---AVG-GVDAGLVPNSCLPATNGQTMELSQEERDALAKTKEGMDLDKFGKWESMFSKEHAASVLTGSSGKSEDKNENVSGKEQRSGDGSTGDAECSTERRGPQESPKPQEPPTTIEMTGLAPWQDGVLERLKTAVDAKDYNMYLVHNGRMLIHFGQMPACTPKERDFVYGNLEAQEVKTVYTFKIPVSYCGKRARLGDAMLRCRPSEHKAVDTSDLGISVEDLP--KSDLIKTTLQCALERELKGHVISESRSIDGLFMDLATQTYNFESEQFSSETVLADLLGTTQSGGLHVELHSECVTRRHNKSSSAFTFTCNKFFRRDEFPLHFKNVHTDIQSCLNGWFQHRCPLAYLGCTFVQNHFRPPGQKAKVIYSQELKTFAIKPEVAPELSEKWKSDHLSGRDGKSLNSLTSLPLEVLQYIAGFLDSISLSQLSQVSVLMRNICATLLQERGMVLLQWKKKRYSHGGTSWKVHNQIWQFSSLFSKIKSWEFNDVTSMSEHLKTCPFNVVEHKTDPIRLTSMCQPQEQARESLVSTFRARPRGRHS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P62932-1", "uniprot_id": "FBX40_MOUSE", "id": "P62932-1", "name": "F-box only protein 40", "aln": "MGRARKPPPALHRHCEGCFNRHCHVPVEPSVSCLVISCHLLCGATFHMCKESEHTLLCPLEQVPCLNSEYGCPLSMARHKLAKHLQVCPASVVCCSMEWIRWPNVDSETFLHENIMKETPSEECLDTALALQDQKVLFRSLKMVELFPETRDATEEEPDMNGDTSWEETGG---AVG-GVDARLAPNSCLPATSRQMMELSQEERDALAKTKEGMDLDKFGKWESMFSKEHAASVLTGSLGKSEDKNGDVAGKEQCSSNVRIGDAEGSAERRGPQESQKSQELPATMEMTGLAPWQDGVLERLKTAVDAKDYNMYLVHNGRMLIHFGQMPACTPKERDFVYGNLEAQEVKTVYTFKIPVSYCGKRARLGDAMLKCRPSEHKAVDTSDLGISVEDLP--KSDLIKTTLQCALERELKGHVISESRSIDGLFMDLATQTYNFEPEQFSSETVLADLLGTAQPGGLHVELHSECVTRRHNKSSSAFTFTCNKFFRRDEFPLHFKNVHTDIQSSLDGWFQHRCPLAYLGCTFVQNHFRPPGQKAKVIYSQELKTFAIKPEVAPELSEKWKSDHLSGRDGKSLNSLTSLPLEVLQYIAGFLDSISLSQLSQVSVLMRNICATLLQERGMVLSQWKKKRYSHGGTSWKVHNQIWQFSSLFSKINSWEFNDVTSMSEHLKTCPFNIVERKTDPIRLTSMCQPQEKARESLVSTFRARPRGRHF-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UH90-1", "uniprot_id": "FBX40_HUMAN", "id": "Q9UH90-1", "name": "F-box only protein 40", "aln": "MGKARRSPPGHHRHCEGCFNRHCHIPVEPNTSCLVISCHLLCGATFHMCKEAEHQLLCPLEQVPCLNSEYGCPLSMSRHKLAKHLQVCPASVVCCSMEWNRWPNVDSETTLHENIMKETPSEECLDTALALQDQKVLFRSLKMVELFPETREATEEEPTMNGETSVEEMGG---AVG-GVDIGLVPHG-LSATNGEMAELSQEEREVLAKTKEGMDLVKFGQWENIFSKEHAASALTNSSASCESKNKNDSEKEQISSGHNMVEGEGAPKKKEPQENQKQQDVRTAMETTGLAPWQDGVLERLKTAVDAKDYNMYLVHNGRMLIHFGQMPACTPKERDFVYGKLEAQEVKTVYTFKVPVSYCGKRARLGDAMLSCKPSEHKAVDTSDLGITVEDLP--KSDLIKTTLQCALERELKGHVISESRSIDGLFMDFATQTYNFEPEQFSSGTVLADLT-AATPGGLHVELHSECVTRRHNKSSSAFTFTCNKFFRRDEFPLHFKNVHTDIQSCLNGWFQHRCPLAYLGCTFVQNHFRPPGQKAKVIYSQELKTFAIKPEVAPELSEGRKNNHLLGHGGKSQNSLTSLPLEILKYIAGFLDSVSLAQLSQVSVLMRNICATLLQERGMVLLQWKKKRYSHGGTSWRVHREIWQFSSLFSKIKSWEFNEVTSMSEHLKSCPFNIVEHKTDPILLTSMCQPREQARESLVSTFRIRPRGRYVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UTA2-1", "uniprot_id": "A0A8N7UTA2_DANRE", "id": "A0A8N7UTA2-1", "name": "", "aln": "MSRYRKSGPRLHRHCETCYNRRCKASIEVSVSCMVINCRLLCGASFHLCKEDEHSLLCPNEKVPCINAHYGCPFTMCRSRLAKHLEVCPASIVCCSMEWNRWPVQNPDAPLYPNLLKELHEQESLDLSMALRDQKHLCARLKMRNCFPELMEEREEEPTPVEEEEDEEAAAGREAVPNGISINEHEGSVLLNGPSKSCEKAMNENVVLNG---DIDKEKYNLFEKMFSMEKGGCKQAEAS-KTEEKKGQKAPSVTKPQDAFIE-----------PKNEETNAPSVDVSKCGLAPWQDGVLERLGQEVKPREFNMYIVHHGRMLISFGQMDACTPRERDFVYGSLEPIPVQTLRSFKVPTSYKQKRIQLREFKARVMT-EHKCVGTSDESTVSENKDGWEMDEMFATLLCYAESEIRGHKISEMVPTDGLYVDIATQTYNFATAPFKYNASLTEVT-ADMDLKLHLELDTETATLRHNKFTSAFSFMCGHFFRRDEFASHFKNVHLDIQSCMGGWFEQRCPLAYLGCTFSQKRLQPATQRAKVFYNRDLSIFTLTPEVPACLQNN-SPNLSEKAHVKYEDSLSNLPFEVLHHIASYLDSFTLSQLALVSRLFRDICATLLQERGMVAFKWRKKSNSLGGARWKPT-IVWEFSTLFSKVENWCIGDTPSMAEHLQNCPFYQTELKTEPFTLTNMSDIKGKGGNNLVSLFMGHK------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: *:. * ***** * :*:*: . * ..**:**.*:*****:**:*** ** **** *:***:*:.****::*.* :*****:*****:******* *** :.:: *: *::** .:*.** ::**:*** * *** : *** : **** : . ** .. ** *:. . * : * : :*. .* .:* *:. :*.:** *:... : : . *.*: : : . . . :. : : . :. ************* *..:::***:**:***** **** ****:*******.**. *:*: :**:*.** ** :* : . ***.*.*** . *: : * : :** * * *::** *** . ***::*:******* . *. : *::: : **:**.:* .* **** :***:* *.:*******. ****** ****.:.***::*********** *::::*. *:***:*.::*. *::.***.. *.: . : * :**:.**:*:*::**.:***.:*:**: ** *:*:************ :*:** * **: *: :*:**:****::.* :.:..**:***:.*** .* **:*: **.*.: : :. :.*** * : ", "identical_positions": 311, "similar_positions": 197, "identity": "43.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-109", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P28335-1", "uniprot_id": "5HT2C_HUMAN", "id": "P28335-1", "name": "5-hydroxytryptamine receptor 2C", "aln": "--------MVNLRNAVHSFLVHLIGLLVWQSDISVSPVAAIVT-----------DIFNTSDGGR-FKFPDGVQNWPALSIVIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYVLRRQALMLLHGHTEEPP-------------------------------------------------------------------------------------------------------------GLSLDFLKCCKRNTAEEENSANPNQDQN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ARRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTNEPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P34968-1", "uniprot_id": "5HT2C_MOUSE", "id": "P34968-1", "name": "5-hydroxytryptamine receptor 2C", "aln": "--------MVNLGTAVRSLLVHLIGLLVWQFDISISPVAAIVT-----------DTFNSSDGGRLFQFPDGVQNWPALSIVVIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDESKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYFLTIYVLRRQTLMLLRGHTEEELR------------------------------------------------------------------------------------------------------------NISLNFLKCCCKKGDEEENAPNPNPDQK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PRR-KKKEKRPRGTMQAINNEKKASKVLGIVFFVFLIMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSKYLRCDYKPDKKPPVRQIPRVAATALSGRELNVNIYRHTNERVVRKANDTEPGIEMQVENLELPVNPSNVVSERISSV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PZA4-1", "uniprot_id": "A0A8M1PZA4_DANRE", "id": "A0A8M1PZA4-1", "name": "", "aln": "--------------------------------MALLNTTASCN-----------VTLDT----------DHSYSWPALFILVIIFFTIAGNILVIMAVSIESKLHNPTNFFLCSLAVADMLVGFLVMPISLISILYNHTWPLPQLLCPLWIFLDVLFSTASIMHLCAISLDRYIGIRNPFSISHTQSSRKAMIKIITVWTISIVLSLPIPVMGLQDEQKVFID-CACVLNEPRFILVGSIVAFFVPLVIMVVCYYLTLHHLQKHSKSFPH-DSKSSCM------------------------------------------------------------------------------------------------------------HSSIETSDTSFLNS---KSSSKMSAFPV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IKRSPLKSRQ--GMNRALENERRASKVLGIVFFLFLIMWCPFFITNVLNAICRDNCS-EYVHKLLDIFVWVGYVSSGVNPLIYTLFNKTYRQAFARYLRCKFH----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KFU6-1", "uniprot_id": "A0A0B4KFU6_DROME", "id": "A0A0B4KFU6-1", "name": "", "aln": "MEEDVYASLGAYNDSGGDDWSSSEHLVLWEEDETQRTTANATSRHNQLHVARWNATGNATISATFEDVPFDANNYWALLALVLVLGTAAGNILVCLAIAWERRLQNVTNYFLMSLAITDLMVAVLVMPLGILTLVKG-YFPLGSEHCLTWICLDVLFCTASIMHLCTISVDRYLSLRYPMRFGRNKTRRRVTLKIVFVWLLSIAMSLPLSLMYSKNHASVLVN-GTCQIPDPVYKLVGSIVCFYIPLGVMLLTYCLTVRLLARQRQNLGGGQQTAAATPGWASGWLGQAPALERRCTWRRLLKPGPGNASSVLHAHSANSTDTDLSTLDNHELWLPDSSIKEPTPTTMTALHQFGAEMLKLSRGLESVASSSTTGSPTKSEFSLSNHLQLQYPSSPQRYAATHQQSHHHNHQQHPAGVYHQQASPKGRHGTTVLGLSTTTLGIERESTRNSLASSRMGGEQSDGTLSQLSQRLRAYKKRRRASSAVPGREKRAGHEDADEDVETPTSTLRRHKRHNSLPKNALYPRHTTVQESLDDDDDEEEESAQQKDQQTKSKICHSDTELDPPQKAKQCHIAGQNHQSDYLQLPSVCTCPYFGDRPLQNCVKSAEVKIISSAFRVTTTTTAVSSSPSEMELLMCSSGNKKSLTSSVSAGITGGPAGAAPATVGSTLSPHSAHNQGSSLTVQSDGSGYLAAPGTPCPGRRKLSISKTASVVTWDSSRHRRRGSSFGGVRTSLLLTPTKTATTSNSSTPLRRSATLRSHQNMNYQGAGECGGKTRTTTSSPCMLQRQQTVRSHHSRNSSVISRNSSRHGRIIRLEQKATKVLGVVFFTFVILWSPFFVLNLLPTVC-AECEERISHWVFDVVTWLGYASSMVNPIFYTIFNKVFRQAFKKVLLCRYSSTSAWRPSRX----QTPVKPGKLKTNTHKCASVDFQDSTAPVRGVLKRSVAVASDI--------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: . :: .: ** ::::: * .***** :*:: * :*:* **:** ***::*::*..****:.::::: . :** * ** *****.********:**:***:.:* *: .: :: :. :** ** :** :*:*:.:: ::. .*::: :* : :* : *:**:*.*::** :*:: * **: * :: : . .:: . :.: : . :. .:. : :. *::*:****:*** *:*:*.***: *:* .:* *. . . ::::..*:**..* :**:.**:*** :*:** . * * : ", "identical_positions": 108, "similar_positions": 128, "identity": "11.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-116", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70560-1", "uniprot_id": "COCA1_RAT", "id": "P70560-1", "name": "Collagen alpha-1(XII) chain", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGEPGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGTPGSPGVAGPSGKPGKPGDHGRPGQSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMSRFNQMLNQIPNDYHSNRNQPGPPGPPGPPGAAGARGEPGPGGAPGFPGRPGVQGPPGERGLPGEKGERG---IGSQGPRGPPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPEPYVPEGGAYLPDREPFIVPVEPERTAEYEDDYGADEPEQQHPDHRRWRRALRPGPGQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60847-1", "uniprot_id": "COCA1_MOUSE", "id": "Q60847-1", "name": "Collagen alpha-1(XII) chain", "aln": "MQTRLPRALAALGVALLLSSIEAEVDPPSDLNFKIIDENTVHMSWERPVDPIVGYRITVDPTTDGPTKEFTLAASTTETLLSDLIPETQYVVTITSYNEVEESVPVIGQLTIQTGGPTKPGEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIVALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYRREDLLAAVKKIPYKGGNTMTGDAIDYLVKNTFTESAGSRAGFPKVAIIITDGKSQDEVEIPARELRNIGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVIEPPSNLVVTELSSKYIRLSWDPSPSAVTGYKILLTPMAAGSRHHALSVGPQTTTLNVRDLTADTEYQISVFAMKGLTSSEPTSVMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLAKSFEISPNRVQISLVQYSRDPHTEFTLKEFNRVEDIIKAINTFPYRGGSTNTGKAMTYVREKIFVPNKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLRFTQVTANSFKAEWSPPGDNVFSYHVTYKDANGDDE--VTVVEPASSTSVVLNNLRPETLYLVNVTAEYEDGFSVPITGEETTAEVKGVPRNLKVTDETTDSFKLTWSQAPGRVLRYRIRYRPVSGGE-SKEVSTPANQRRKTLENLTPDTKYEISVIAEYSSGPGSPLTGNAATEEVRGNPRDLRVSDATTSTLKLSWSRAPGKVKQYLVTYTPAAGGETQEVTVRGDTTTTMLRKLKEGTQYDLSVTALYASGAGEALSGKGSTLEERGSPQNLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDIEAGETTLPGDAIHTMIENLQPETKYKISVFATYSSGEGEPVTGDATTELSQDSKILRVDEETEHTMRVTWKAAPGKVVNYRVVYRPQGGGRQMVAKVPPTVTSTVLKRLQPQTTYDITVLPMYKTGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVLGPYDNTVVLEELRAGTTYRVNVFGMFDGGESLPLVGQEMTTLSDTTVTP-FLSSGMDCLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFEIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQSFKTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSKIVDDLTINLCNSVKGPGD-LEAPTNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRLDTSTVLKDLKPETDYVVNVYSVVEDEYSEPLKGTEKTLPVPVVS-LNIYDVGPTTMHVQWQPVGGATGYTVSYQPTRSPEGTKPKEMRVGPTVNDVQLTGLLPNTEYEVTVQAVLYDLTSEPAKAREVTLPLPRPQDVKLRDVTHSTMNVVWEPVLGKVRKYIVRYKTPDEEFKEVEVDRSRASTILKDLSSQTQYTVSVSAVYDEGTSPPATAYDTTRRVPAPTNLQFTEVTPESFRGTWDHGASDVSLYRITWAPVGNPD-KMETILNGDENTLVFENLNPNTPYEVSITAIYPDESESEDLSGTERTLRLIPLTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTITVGGRQNSVLLQKLKPDTPYTITVYSQYPDGEGGRMTGRGKTKPLNTVR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLRVYDPSTSSLSVRWDHAEGNPRQYKLFYAPTSGGPEELVPIPGNTNYAILRNLQPDTPYTITVVPVYTEGDGGRTSDTGRTLVRGLARNIQVYNPTPNSLDVRWDPAPGPVQQYRIVYSPVAGTRPSESIVVPGNTRTVHLERLIPDTPYSVNIVALYSDGEGNPSPSQGRTLPRSGPRNIRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAIYEDGDGGHLTGNGRTVGLLPPQNIHIFDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEVTSYTLHNLNPSTTYDVSVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQVGWDTFCVKWSPHRAATSYRLKLSPADG--TRGQEITVRGSETSHCFTGLSPEAEYGVTVFVQTPNLEGPGVPIKEQTTVKPTEAPTEPPTPSPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGAFDEVNPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAAFVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRLQKNAFINQPTAELHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYRPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTDEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEILGKLLK---GERKSATFQIQSFDIVCSPVWTSRDRCCDIPSRRDEAKCPALPNACTCTQDSVGPPGPPGPAGGPGAKGPRGERGINGAVGPPGPRGDTGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGQSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMSRFNQMLNQIPNDYHSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG---TGSQGPRGPPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPEPYVPEGGAYLPEREPFIVPVEPERTAEYEDDYGADEPDQQHPDHMRWRRALRPGPAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99715-1", "uniprot_id": "COCA1_HUMAN", "id": "Q99715-1", "name": "Collagen alpha-1(XII) chain", "aln": "MRSRLPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSVSAWTDLVFLVDGSWSVGRNNFKYILDFIAALVSAFDIGEEKTRVGVVQYSSDTRTEFNLNQYYQRDELLAAIKKIPYKGGNTMTGDAIDYLVKNTFTESAGARVGFPKVAIIITDGKSQDEVEIPARELRNVGVEVFSLGIKAADAKELKQIASTPSLNHVFNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDE--VTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGE-SREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMP-ILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGD-LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVS-LNIYDVGPTTMHVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSD-KMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSER--TLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRAATSYRLKLSPADG--TRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPPPPTIPPARDVCKGAKADIVFLTDASWSIGDDNFNKVVKFIFNTVGGFDEISPAGIQVSFVQYSDEVKSEFKLNTYNDKALALGALQNIRYRGGNTRTGKALTFIKEKVLTWESGMRKNVPKVLVVVTDGRSQDEVKKAALVIQQSGFSVFVVGVADVDYNELANIASKPSERHVFIVDDFESFEKIEDNLITFVCETATSSCPLIYLDGYTSPGFKMLEAYNLTEKNFASVQGVSLESGSFPSYSAYRIQKNAFVNQPTADLHPNGLPPSYTIILLFRLLPETPSDPFAIWQITDRDYKPQVGVIADPSSKTLSFFNKDTRGEVQTVTFDTEEVKTLFYGSFHKVHIVVTSKSVKIYIDCYEIIEKDIKEAGNITTDGYEILGKLLK---GERKSAAFQIQSFDIVCSPVWTSRDRCCDIPSRRDEGKCPAFPNSCTCTQDSVGPPGPPGPAGGPGAKGPRGERGISGAIGPPGPRGDIGPPGPQGPPGPQGPNGLSIPGEQGRQGMKGDAGEPGLPGRTGTPGLPGPPGPMGPPGDRGFTGKDGAMGPRGPPGPPGSPGSPGVTGPSGKPGKPGDHGRPGPSGLKGEKGDRGDIASQNMMRAVARQVCEQLISGQMNRFNQMLNQIPNDYQSSRNQPGPPGPPGPPGSAGARGEPGPGGRPGFPGTPGMQGPPGERGLPGEKGERG---TGSSGPRGLPGPPGPQGESRTGPPGSTGSRGPPGPPGRPGNSGIRGPPGPPGYCDSSQCASIPYNGQGYPGSG-------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YUY1-1", "uniprot_id": "A0A8M6YUY1_DANRE", "id": "A0A8M6YUY1-1", "name": "Collagen alpha-1(XII) chain", "aln": "-MSVRHLAAVALFTLAALTSVRAQVMPPSDLRFKILNENTVQMTWKQPLSRVDGFRVQVTSDTEEPVKEFTLSPTSTKTSIRDLTPDVDYVVTITSYLGSEESIPISGQITIQS-SGFEGGTRKPQVSDAVKCSIGAIADLVFLVDGSWSVGRENFKFIRNFIAALAGAFDLGEDKTRVGVVQYSTDTRTEFNLNQHFRRVDLLRAINNLPYKGGNTMTGEALDYLLKNMFTEAAGARKGFPRVAVVITDGKSQDPVEGYAKKLKNAGVELFTLGIKEADEEELKQMSSTPYRTHVYTVPNFDMIKAVEKSFIAQVCSSVDDQLNSLASGEEVVEPASNLQVTEVASKSMRVTWDASIGEVTGYKVQMVPMLAGSKRQELYVGPTQTSVNVRDLSPDTEYEISLFALKGLTPSEAVMAMEKTQPLKVSLECSLGVDVQADIVLLVDGSYSIGITNFAKVRAFLEVLVNTFDIGPNKVQISLVQYSRDPYTEFYLNTHHDLNAVVKAVRTFPYRGGSTNTGKAMTYVRERIFIATRGARENVPRVTILITDGKSSDAFKDPAAKLRNTDVEIFAVGVKDAVRSELEAIANPPAETHVYTVEDFDAFQRISNELTQSICLRIEQELLNIKRRSLVAPRSLTLSEVTSRSFRASWEIDAVDVQAYLVQYKPDADAEASYTSVSIPGDSTTTVLYHLTPVTKYEVKVYAQYEKGESFPLSGYETTLDELGSVTNLKVSEETSSSFRVSWREAPGPVVRYRLTYIPVQGDSGLLETATVGPETTIVLQQLYPVTTYRVSVAAEYPSGVGPQMQIDGTTKEELGSPRDLRVSDETVSSMQLSWAAAPGRVLQYSVFYQSTITAVTKAVTLKGDTTSTMLKNLEPGTEYNLSVSARYSSGQGASLQGVGTTLEELGSPRDLITSDVTDTSFMVSWTAAPGRVRQYLVRWRSLFS-GESGEKLVPGDVTSTLLENLSPETRYQVSVFAAYDRGNGEPLVGEETTDASASAKALLVSDETERTMRVIWKAAPGPVVNYRLTYIPQTGGKEMTMKIPANVTSTMLRKLQHTTTYFITVHPIYKRGEGKARQGVGTTLSPYKAPRNLQTSEPTKTSFRVTWDPAPGDVRGYKVTFHPSENDIDLGELLVGPYDNTVVLEELRAGTKYSVAVFGMFDGGQSMPLAGEEKTTLSDAPDSPPVKYSGNECKTSAKADIVLLVDGSWSIGRLNFKTIRAFIGRMVGVFDIGPDKVQIGLAQYSGDPKTEWHLNAHPTRASLLDAVANLPYKGGNTMTGMALNYILQNNFRPNVGMRPDSRKIGVLVTDGKSQDEIVVNSQRLRDSGIELYAIGVKNADENELRSIATDPDEIHMYNVNDFSFLLDIVDDLTENLCNSVKGPGGGPGTPTDLETSEVTHYSFRATWMPPDEPVERFRIEYVPAAGGKTEVLFVDGEENTLVLVNLNPMTEYIVRVYGVIGEESSEPLKGTETTLPLPAVTSMSVYDEALTSMRVRWELVKGASGYLLNYNAINASVPSGMMEMRVGADVNDVQLLQLLPNTAYSISLFALHGEAASQPLIDRGVTLPLPPAGKLKITEVTHSSMRLTWDAAPGNVRKYIITYKREDGELKELEVNGDITTMVLTNLRSQTEYDVAVTPVYDEGSGNPMLGTAITDVVPAPKNLRFSEVGQTSFRATWEHGAPDVGMYRIGWSKKGDRENVKSEILAREETSHLLTELDPDTEYDVTVTAIYPDESESEDLMGSQR--TLSKLITPVPTGPPQNLQVFNATTTTLTVKWDHAPGPVQSYKVTHQPVAG-GKPLSVQVGGKKNSVILQKLTPNTPYTITVAAVYRTGESKDISGQGRTKPLGGVRNLQVLNPTMTTLNVRWEPAEGKVKEYKVVYVPAAGGAESMVGLEQVSGATTNTVLRGLQSDTLYTVTLIPVYAEGEGQRMSENGKTRALGGVKNLRVTDPTMTSLNVKWDPADGAVRQYKIFFVPAAGGTEAMETVPGPQNTIVLRNLQPDTVYTVSVVPVYPATEGRRQSENGKTLPLGGVRNLRLIDPTFTTLTATWEAADGNVQGYKVIYVPTGGGTELMEQVSESTTTLVLQKLMPDTMYTVTVLPVYAEGDGPRLSEKGKTKPLGSVRNLQVTDPTISTLNVRWEPAEGNVREYIVIYVPAGSQDQEVDQVPGTTTSTVLKNLEPDTTYTVTLVPVYHEMEGKSLSENGKTKPLGGVRNLQVTDPTSSTLNVRWEHADGNPRNYKVFYIPQPGDAEMMELVSGGTTSTVLRNLNANTMYKVTLLPMYENDVEGKRQSENGKTKPLGSVKNLQVTDPTVNSLRVRWDAADGDVRQYNVIYVPVAGGAAGQTQVSGMSTNTILRNLQPNTEYKVTVVPVYADAEGKRQSANGKTKPLGGVKNLQVTDPTTSSLKVRWEPAEGNVRQYRIFYVPASGGAEDMEQVSGGTTNTILRNLLSDTVYTVTVVPVYPEGEGLRQSEKGKTLPRLPPRNIKVYNPTPNSLNVRWEPASGQVQQYRVAYAPLTGIRPLESVLVPGNLNNAFLDQLVPDTPYSVNVMAVYADGEGPGIDGNGKTLPRAGPRNMRVFETTTSTISIGWDHAEGPVQQYKISYASLTGDPITEFTVVPGNRNNAMLQNLHPDTPYNITVTAVYPEGPGGSLNGNGKTLGLLAPQNLRVSDEWYTRFRVSWDPAPSPVMGYKLVYQPTTKDESLEVFVGDVTSYTLHNLLPGTTYDVQVYAQYDGGVSKPLIGQGTTLYLNVTNLESYDVGYNRFCIKWTPHRAATSYRIKLNPVDPSAKGQQEITITASQSQYCFEGLSQDSLYTATVFVQTPNLEGPGVGTKERTRVKPTPVPTKPPTPPPPPTIPPGWAVCKGAKADVVFLIDGSWSIGDESFSKVIQFVFSVVGAFDVIGPTGMQISFVQYSDDANTEFRLNTYKDKGTALSALKLIRYQGGNTKTGVALKHVYEKVITVENGMRRNVPKVVVAVTDGRSQDDVHKNAAKLQHAGYSVFVVGVADVDFVELQNIASKPSERHVFVVDDFDAFSTIQDNLVTFICETATSSCPLIYVNGFTSPGFRMLEAFNLTEKMYASTKGVSMEPGSFNSYTAYRLHKNAFLSQPSSYIHPDGLPSTYTIILMFRLLPDSPNEAFDIWQVSDKNYKPETGVTIDPSAQSVSFYNKDTTGEIQRATFKNDQVKRIFHGSFHKLHILVSSKSVKLNVDCHEVAEKEIKPAGNTSTDGFQVLGKMSKSIGSKGESATFQLQMFDIVCSLGWTSRDRCCDLPSMRDESKCPALPNACTCTSDSSGPPGPQGPVGAPGSKGPRGERGEPGQVGPVGTRGEMGMPGPMGPPGPQGPSGRSIPGEAGRQGPKGDPGDAGLPGQKGPPGPTGAIGPVGPAGIRGPPGKEGPVGPMGPQGAMGPPGAPGMPGPAGKPGKNGDTGVPGLTGVKGDKGERGDIASQSMMRSIARQVCEQLVNGQMGRFNDMFNQIPSNYHS--NSPGPSGPPGPPGPQGPRGEPGRLGRNGLPGSPGLPGRQGERGTPGEKGERGSPGVGERGQRGPSGPPGPPGESRTGPTGSSGPPGIRGPPGRNGVAGVRGPPGPPGYCDSSMCVSMQYNGQGYREEFPPDAER--------VVPIPDEDFEISANQRRRRSPPETGPKRKAW----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *** **** ***.*:.****:.*.** .*. **:**.* ** .**:*.:** ** *. *.**:**:.**:***** ** * ** :*:**:**:*******.***::********:.***.***:*:****.:*:* *.***.*******. *.***** * *:** **: * **** ******** *. * ** .***** *******.**:*. * ***** * :*:************* *.*: ****** ", "identical_positions": 171, "similar_positions": 50, "identity": "4.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-12", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8WU66-1", "uniprot_id": "TSEAR_HUMAN", "id": "Q8WU66-1", "name": "Thrombospondin-type laminin G domain and EAR repeat-containing protein", "aln": "---------MSALLSLCFVLPLA-APGHGTQGWEPCTDLRPLDILAEVVPSDG-ATSGIRIVQVHGARGLQLSVAAPRTMSFPASRIFSQCDLFPEEFSIVVTLRVPNLPPKRNEYLLTVVAEESDLLLLGLRLSPAQLHFLFLREDTAGAWQTRVSFRSPALVDGRWHTLVLAVSAGVFSLTTDCGLPVDIMADVPFPATLSVKGARFFVGSRRRAKGLFMGLVRQLVLLPGSDATPRLCPSRNAPLAVLSIPRVLQALTGKPEDNEVLKYPYETNIRVTLGPQPPCTEVEDAQFWFDASRKGLYLCVGNEWVSVLAAKERLDYVEEHQNLSTNSETLGIEVFRIPQVGLFVATANRKAT--SAVYKWTEEKFVSYQNIPTHQAQAWRHFTIGKKIFLAVAN-FEPDEKGQEFSVIYKWSHRKLKFTPYQSIATHSARDWEAFEVDGEHFLAVANHR-EGDNHNIDSVIYKWNPATRLFEANQTIATSGAYDWEFFSVGPYSFLVVANTFNGTSTKVHSHLYIRLLGSFQLFQSFPTFGAADWEVFQIGERIFLAVANSHSYDVEMQVQNDSYVINSVIYELNVTAQAFVKFQDILTCSALDWEFFSVGEDYFLVVANSFDGRTFSVNSIIYRWQGYEGFVAVHSLPTVGCRDWEAFSTTAGAYLIYSSAKEPLSRVLRLRTR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "J3S6Y1-1", "uniprot_id": "TSEAR_MOUSE", "id": "J3S6Y1-1", "name": "Thrombospondin-type laminin G domain and EAR repeat-containing protein", "aln": "---------MSALLMLCAVLLLLGTPSRGARPWEPCTDLRPLDILAEVVPLNG-ATSGIRMVQVEGVRGLQFSATEPRTTSFPASRIFSSCDFFPEEFSIIVTLRVPNLPPKKNEYLLSLLAEERDTLLLGLRYSPTQLHFLFLSEDLAGAWQTRVSFWSPGLMDSRWHTLILAVSQGSFSLTTDCGLPVDIMADVSFPPTLSVRGARFFIGSRKRTKGLFTGVIRQLVLLPGSDATPQLCPSRNARLAELSIPQVLKRLTGKPDDNEVLNYPYEADMKVTLGSRPPCTKAEGAQFWFDAAQKGLYLCAGSEWVSVLAAKTKLDYVEEHQSLHTNSETLGIEVFSIPGVGLFAAAANRKAR--SAIYKWTDGKFVSYQNIATHQAQSWRHFTIGKKIFLAVAN-FGPNERGQEFSVIYKWSPRKLKFTLYQRIATHSARDWEAFEVDGEHFLVVANHR-EGDNHNIDSMVYRWNPSSQLFEANQSIATSGAYDWEFFTVGPYSFLVVANTFNGTSTQVHSHLYIWLVGAFQLFQSFLTFGAADWEVFHIGERIFLAVANSHSYDVQMQAQNDSYVLSSVIYELNITAQTFVKFQDIPTCSALDWEFFSVGEDHFLVVANSFDGNTFSVNSIIYRWQGYEGFVAVHKLPTFGCRDWEAFNTTAGSYLIYSSAKEPLSRVLKLRTG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7EY40-1", "uniprot_id": "E7EY40_DANRE", "id": "E7EY40-1", "name": "", "aln": "MEGHQDLLPSSWLLTFLLLLLMSLTGSVTVVPWKPCTDLHPVDLLSRVLPRNGEAQAGVRMVQEGGARGVQFFRPT-QTLTFPSSQLFVNCPHFPAEFSIVATVKMPHTRVKRNEYLLAVVKEDVNQLLLGLRFSKEKVHLIYQGSTGK----ERLSFKRVRMADNHWHSMVLAVSGHHATLTLDCGIPLELVHKQPFPSDLSTGGSRFHIGSRRKWKGLFSGLLRQLVLLPGSDATSRVCPSSRPSLVELSVPTFLSNLPAISHMNDVLVPPYETEVRVTLGSKPACTAAEQGQLWFDTLKRGLFLCDGTYWHSMLQDKDRLDYVDDHQDLYTSSETLDIELFQIPSVGLFAAMAHRATKPGSGIYRWSHGHFQLYQNISTFKAQAWKQFTIGKKMFLAVSNSMGPADGEPELSVVYRWSNKRLKFVPYQTLETHSARDWEAFQINNEAFLAVANHRTENGNHNIESVVYKWNPGTKTFEVNQTILTSGAYDWEFFTVGPYHFLAVANAFDGTSTQTDSSIYIWLGGAFQVFQTIRTFGATDWEMFQIGNRVFLAVANGH---MLCEKGPSLYTINSTIYELDMTTKMFLKFQDIVTYSAVDWEFFTVGDEHFLVVANSYDGSSYSLNSVIYRWQGYEGFVPVHRLPTIGCSDWEFFTSAEGSYLMYSSAKAPLSKVFKLRIH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ** : :* : : . . *:*****:*:*:*:.*:* :* * :*:*:** *.**:*: . :* :**:*::* .* ** ****:.*:::*: *:*****::: *: : ****** * ::*::: . *:** : *.:**:::**** :** ***:*:::: . .**. **. *:**.:***:: **** *::************.::*** .. *. **:* .*. *.. .. *:** ***::::****.:*.** .* .*:***: ::**:** *. * *:* * :****::**.* *.****.**:* ** ****.* *:* : *.:*:*:. :* ****.*.:**:*::******:****:* : * : *:**:*:** ::***. ** : **********:::.* **.***** *..****:*::*:***.:: **.**:* **********:**** **.***:*:****:..* :** * *:**:**:: ****:***:*:**:*:******.* : : . *.:.*.****::*:: *:***** * **:*****:**:::*******:** ::*:**:***********.** ***.** *** *.:: *:**:***** ***:*::** ", "identical_positions": 347, "similar_positions": 198, "identity": "50.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-128", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q01721-1", "uniprot_id": "GAS1_MOUSE", "id": "Q01721-1", "name": "Growth arrest-specific protein 1", "aln": "MLAALLGGAG-ARTGTLPGALLCLMALLQLLCSAPRGSGLAHGRRLICWQALLQCQGEPDCSYAYSQYAEACAPVLAQRGGADAPGPAG-AFPASAAS-SPRWRCPSHCISALIQLNHTRRGPALEDCDCAQDEHCRSTKRAIEPCLPRTSSVGPG-AGAGSVMGCTEARRRCDRDSRCNLALSRYLAYCGKLFNGLRCTDECRAVIEDMLAVPKAALLNDCVCDGLERPICESVKENMARLCFGPDASNGPGSSGSDGGLDDYYDEEYDDEQRAGAAGGEQPLDDDDGL---ARPGGGAAAAGGRGDLPHGPGRRSSSSGSGGHWANRSAWTPFACLLLLLLLLLGSHL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P54826-1", "uniprot_id": "GAS1_HUMAN", "id": "P54826-1", "name": "Growth arrest-specific protein 1", "aln": "MVAALLGGGGEARGGTVPGAWLCLMALLQLLGSAPRGSGLAHGRRLICWQALLQCQGEPECSYAYNQYAEACAPVLAQHGGGDAPGAAAAAFPASAASFSSRWRCPSHCISALIQLNHTRRGPALEDCDCAQDENCKSTKRAIEPCLPRTSGGGAGGPGAGGVMGCTEARRRCDRDSRCNLALSRYLTYCGKVFNGLRCTDECRTVIEDMLAMPKAALLNDCVCDGLERPICESVKENMARLCFGAELGNGPGSSGSDGGLDDYYDEDYDDEQRTGGAGGEQPLDDDDGVPHPPRPGSGAAASGGRGDLPYGPGRRS--SGGGGRLAPRGAWTPLASILLLLLGPLF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TDN8-1", "uniprot_id": "A0AB32TDN8_DANRE", "id": "A0AB32TDN8-1", "name": "", "aln": "-------------MGSILAFFISLLMTLD--------------AQLVCWQALIRCHEERDCELAYNQYLTACDGNIR----------------------GSRKQCPSHCISALIRLNQTSSGTHLESCDCGIDVECLRAKRAIEPCMPRTH------PGDAEGMGCTEARQRCEEEPRCQESLNAYLSRCGQLFNGRKCSSRCKSTIEELLFMPNGVLLNQCVCDGLERPFCEVVKQNMAKLCAIGDHSISIEHDGTD---DLYEDEDYE-----GKPDGE--VTDSDAVS----------------------------------ISSALTFTPQVVLICIGFALAGF--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:: . :.*: *: :*:*****::*: * :*. **.** ** : ..* :**********:**:* *. **.***. * .* :*******:*** .* . *******:**:.:.**: :*. **: **::*** :*:..*::.**::* :*:..***:*********:** **:***:** : . . .*:* * * **:*: * ..** : *.*.: : ::** . :: : : ", "identical_positions": 111, "similar_positions": 78, "identity": "31.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-131", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5SXG7-1", "uniprot_id": "VMO1_MOUSE", "id": "Q5SXG7-1", "name": "Vitelline membrane outer layer protein 1 homolog", "aln": "MELQAGARLL-LLLGVMCYG--HAQIQVHVEPRYASIVDVTNGGTWGDWAWPEMCPDGYFASGFSVKVE--PPQGIPGDDTALNGIRLHCTRGNSQKNT-----HVVESQSGSWGSWSEPLWCPGTSFLVAFCLRVEPFTFPGDNTGVNNVRFRCS-DGVELEGPGLNWGDYGEWSNSCP-KGVCGLQTKIQKPRGLRDDTALNDIRIFCCAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z5L0-1", "uniprot_id": "VMO1_HUMAN", "id": "Q7Z5L0-1", "name": "Vitelline membrane outer layer protein 1 homolog", "aln": "MERGAGAKLLPLLLLLRATG--FTCAQTDGRNGYTAVIEVTSGGPWGDWAWPEMCPDGFFASGFSLKVE--PPQGIPGDDTALNGIRLHCARGNVLGNT-----HVVESQSGSWGEWSEPLWCRGGAYLVAFSLRVEAPTTLGDNTAANNVRFRCS-DGEELQGPGLSWGDFGDWSDHCP-KGACGLQTKIQGPRGLGDDTALNDARLFCCRS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1RCF0-1", "uniprot_id": "F1RCF0_DANRE", "id": "F1RCF0-1", "name": "", "aln": "MLKFLSLLLISTLAVFAANASPSGRVQRSIGRPFRSMLTVHNGMRWGSWGQKEMCPTGMYAAGFSLKVAGMWESLLVGDNTALNGIRLHCINPSKKSSAPYDDYATVQSDVGSWGKWSDIKWCP-SGFLMSFQLRVEPYQGTWDDTAANNIRFKCSVNAEELQGSGMSWGEWGDWSETCGGTGICGIETMVEEPQGVADDTALNDLRIYCCD-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . *: * . . . * : ::: * .* **.*. **** * :*:***:** . : **:********** . . .: .*:*: ****.**: ** .:*::* ****. *:*..**:**:** :. **:*.*:.**::*:**: * .* **::* :: *:*: ******* *::** ", "identical_positions": 82, "similar_positions": 56, "identity": "38.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-133", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P78369-1", "uniprot_id": "CLD10_HUMAN", "id": "P78369-1", "name": "Claudin-10", "aln": "MAS----TASEIIAFMVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYWANLWKACVTDSTGVSNCKDFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFCFSISDNNKTPR--YTYNGATSVMSSRTK---YHGGE-DFKTTNPSKQFDKNAYV---------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z0S6-1", "uniprot_id": "CLD10_MOUSE", "id": "Q9Z0S6-1", "name": "Claudin-10", "aln": "MAS----TALEIVAFVVSISGWVLVSSTLPTDYWKVSTIDGTVITTATYFANLWKICVTDSTGVANCKEFPSMLALDGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDQAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLYMEQKYELGAALFIGWAGASLCIIGGVIFCFSISDNNKTPRMGYTYNGPTSAMSSRTK---YQGGEGDFKTTGPSKQFDKNAYV---------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8N7T7D3-1", "uniprot_id": "A0A8N7T7D3_DANRE", "id": "A0A8N7T7D3-1", "name": "", "aln": "MASRTVIMYVEIACFVSCLSGWVLICSTMVTEYWIVSESAEVVLAAGDFYSNLWMDCVSDATGASDCKYFPSMMDLPAFLHISRALAVIAVIFGFWGAVLTLIGMKCTKIGGSELVNARITFAAALTYMASGLSGMTVYSWWGEKSRSEYLDPYYLDLKYELGAALFIGWGGSCLIIGGSGVMGYFSGKEAFPQSFSKQFRKPPTYLTARTRRTYMMGSRPTTVVIPPSQQSYSKRRASRVSRASRGRTETQESQSSRSVRPAWPLLDSVV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ** .*: .:*****:.**: *:** ** .*:::. :::*** **:*:**.::** ****: * .::: .*.* : ** :**:*::::*:******:***: .:*:*: *.:.:: ***..** * :.:* :*::** ::: ************.*:.* * *. :: : ..: . :. ..: :::**: *.. . **:* .: . ", "identical_positions": 86, "similar_positions": 85, "identity": "31.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-134", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZBB5-1", "uniprot_id": "D3ZBB5_RAT", "id": "D3ZBB5-1", "name": "", "aln": "MRRGVPQSPSRKRKLGGRDKGGRDVSAVNSFFLKYSFPYVWALLRLREMVRSGSRPGQVIPSGRQPG-SKLPNGKKGTHVRKVAHFNVDPACPAYSDSESQTDTVQGLDSCASLLRDILKNEDSGSEVVYSENRSNSKPLEGRKNRSKKKGPEKH-VPTVVRKEILSSENKRWMPNETSTG-----SDIAQHWSVQDHYRMYSPIIYQALCEHVQTQMSLMNSFASKHGPNGRPAV-CHTGSNSDSQAMSHSGFGWS-SASVWPPQQPSCHLTVHSEVQTDDDNQFDSQGQTTPVRHRDAPRTLSSIHPGVAHGPPHSDGAAASKIQQLNLGSWVLPQQRAPKEAELPKRFQTHVSLFPAHGKDALSDSQAHPSPSHLPPVFLATNEEKCAREQIGEATNEGKYLSIHEQDAKLAKNVQQAEN-VSQTAEKVRIAKCLLGELKALTEEQEDSEVQRLLTEVEACISGLSAVSGHINVEVEIALALQPLRSENAQLRRQLRILNQRLREQEKSTETP----ANLKLFSLRSL--SLQNQLQESLKSQELLQSKNEELLKVIEDQREENRRFSTLFKDEEQALLHSRQQFDMEMTRVKMELEEALANEKNSRFKLETAEKENQILGITLRQRDAEVARLRELTRTLQNSMRKLLSDLHVDTARCKMGNSLTRSLLNVYDQQFQRDPAPPHISIMSYLNKLETNQSFIQSELP---NNEETPESDSLCENVLPSQRPPHSDARAVDGGPAPGTVSAALVEDSDTDCEAVTVVEDGCDVDSTFYIPFARSTSKKHSPPSKRLSPQAKVSAAAS-----AGACASKKESKPCAPAVCPS-RDKAEDAPGNLSGTYDTEDVQLLRKIREALGKIPAAAGHPKEQATHRGPPAPLSPGVPVKGNIVADSSFLHSDLMSDWSISSFSTFTSRDEQDFRNGLAALDANIARLQKSLKTGLLEK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K2J4-1", "uniprot_id": "CCD14_MOUSE", "id": "Q8K2J4-1", "name": "Coiled-coil domain-containing protein 14", "aln": "MSPGGPRPSSRKRKLRGRDKGGPDISAVNSFFLKYSFPYAWALLRLREMVRSGSRPGQVISSGRQPG-AKLPNGKKGTHVRKIAHFNVDSACPVQSDSESQTDTLQGLDGCASLLRDILKNEDSGSEMVYSENRCNSKPLEGRKNRSKKKGPEKH-VPSVVRKEILSSENRKWISNEASTG-----SDTAQRWSLQDHYRMYSPIIYQALCEHVQTQMSLMNSLALKNGPNGIHAV-CHTMSNSGSQATPHSGFGCSPSASVWPPQQPSCPLMVHSEVQTDADNQFESQSQATSVKYGDVPRDPFSVHPGVACGLPHADSPAVAKSRQLDLTSCILPQQRAPKEAELLKCFQTHTSLFPAHGKDALSDSQAYQSPSQLQPAFLATNEEKCAKEQFEEATNEGKHLSTHVQDAKIAKNVQQAEN-VSQTAEKIRLAKCLLGELKALMEE--DSEVQRLVTEVEACVSGLSAVSGHPNVEVEIALALQPLRSENAQLRRQLRILNQRLREQEKTEKGP----GNLELFSLQSLNMSLQNQLQESLKSQELLQSKNEELLKVIENQKEENKKFTTLFKDKEQTLLHNKQQFDIEMTRVKMELEEALANEKNLRFKLETAEKESQILGITLRQRDAEVARLRELTRTLQSSMAKLLSDLSMDTARCRMGNSLTKSLLNVYDQQLQQDPAPAQTSIMSYLNKLETNHSFIHSKLL---NNEAAIEPDRLCESVLPPQRPPHSDAGTADGGSASGTVSAASVEDSDMDCETLTVIEDGCNVDSTVYIPFARNTSKKHSPLCKRLSPQPKLSVAAAQLVS-GSAQTSKGESKPRAPAVCSS-RNEAEDAPGDLSSTYDTEDVQLLRKIKEAIGKIPAAAEHAKEQATHHGPSAHPSPGVPVKGSIVPDSSFLNSDLMSDWSISSFSTFTSHDEQDFRNGLAALDANIARLQKSLKTGLLEK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q49A88-1", "uniprot_id": "CCD14_HUMAN", "id": "Q49A88-1", "name": "Coiled-coil domain-containing protein 14", "aln": "MKRGIRRDPFRKRKLGGRAKKVREPTAVNSFYREASLPSVWASLRRREMVRSGARPGQVLSSGRHTGPAKLTNGKKATYLRKIPRFNADSGYSIHSDSESQAETVHGLDGCASLLRDILRNEDSGSETAYLENRSNSRPLESKRYGSKKKRHEKHTIPLVVQKETSSSDNKKQIPNEASARSERDTSDLEQNWSLQDHYRMYSPIIYQALCEHVQTQMSLMNDLTSKNIPNGIPAVPCHAPSHSESQATPHSSYGLCTSTPVWSLQRPPCPPKVHSEVQTDGNSQFASQGKTVSATCTDVLRNSFNTSPGVPCSLPKTDISAIPTLQQLGLVNGILPQQGIHKETDLLKCIQTYLSLFRSHGKETHLDSQTHRSPTQSQPAFLATNEEKCAREQIREATSERKDLNIHVRDTKTVKDVQKAKN-VNKTAEKVRIIKYLLGELKALVAEQEDSEIQRLITEMEACISVLPTVSGNTDIQVEIALAMQPLRSENAQLRRQLRILNQQLREQQKTQKPSGAVDCNLELFSLQSLNMSLQNQLEESLKSQELLQSKNEELLKVIENQKDENKKFSSIFKDKDQTILENKQQYDIEITRIKIELEEALVNVKSSQFKLETAEKENQILGITLRQRDAEVTRLRELTRTLQTSMAKLLSDLSVDSARCKPGNNLTKSLLNIHDKQLQHDPAPAHTSIMSYLNKLETNYSFTHSEPLSTIKNEETIEPDKTYENVLSSRGPQNSNTRGMEEASAPGIISALSKQDSDEGSETMALIEDEHNLDNTIYIPFARSTPEKKSPLSKRLSPQPQIRAATTQLVSNSGLAVSGKENKLCTPVICSSSTKEAEDAPEKLSRASDMKDTQLLKKIKEAIGKIPAATKEPEEQTACHGPSGCLSNSLQVKGNTVCDGSVFTSDLMSDWSISSFSTFTSRDEQDFRNGLAALDANIARLQKSLRTGLLEK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AT55-1", "uniprot_id": "A0A8M3AT55_DANRE", "id": "A0A8M3AT55-1", "name": "", "aln": "------MAKQGVSRLKVVSSGRLTASGRGQTHKKKVAGTCLSPLEPGYSLYSTDSEDQVTTIHKGLD-------RCAALLDGILQAEQTESKPKPQGTKTCTFKSKPKNLSRKFETDNKKKHWNKTKTAIHANK---RPAPVQKKILSAKCHVGLAGQLCSRNDQSSGIRKKQVSHDQPSG-----LTTEHGQQISLPLSSSQPAASCNHPGQVHTSTVFNTRLTTSTPAMSPQRPGSAPTEPCTSKCTLSSG---CPSEEFHQLRTMSAAIPSCPHGSVEISGISNKHAATFSMPSAAQRQTPVAVSPVHNESCTPVPASPVSSVHELGSVEPSVSLVSSVGSLSCSSSTLIETQMSIQPQAQTDPDGAILIVCNGQGNLKEDNGSAEDEMEKHGKDITPVRDISCQTSTETLTALTHKTKASPVKTAQKVMTVKYLLGELKTLVAN-HDGDAVRLISEVEQNISLLPVMVGSTNIQAEIALAVQPLRSENVQLRRRLRILNQQLLERERAERQTRPEACDMEVVALQSLNLTLQTQLNESREELDVLQQENMRLRKAAE--------------DKDGDLKHLKDLCELENSRLRLDVSEALAEMQSCQSKLKESETEKMALNLSLQQREAEIGKLQDIIRNLQKSQTNVSYSPHQDVLQPN--SQLTKSVLELHEAAASDKPSNSVKTYLQTLEDIRQASPSNHIKCRS--EKLHPGQTDGKNYDILLSDTKICLKTDRDIHKPTLETIAEDMPQLEDQKKTVFAPLRETPLVQLACSDPLTHCN-QQIAARNHRKDVDVELKYVGR------GLEKLDISGLHIQNATCEG--------------RDYLGVGLHLNQQNNGLNNQPVQTQHVHRFPRLAVQSAYTGRPSAMDSTIS---SCDIKSLASDWSINSWSTFNTQDEQNFRDGLAALDASIESLQKTLKVDLNK-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . :. .. . : : *. : * .** . : . : .: : : : : . . ..::: : . : : . .: * ::. . :: . *: :* :: . * ::: *. .:: :.:: .: : .:. .* :*:*. : . :: . . . . . . . *:. *. . * . : .. .. ..: .. .:. : . : * . . .. .. ::*. . :. . . . .: :: *. . ... : *: : . : :. : . . .:::: :**:*: * ******:* : *.: **::*:* :* *..: * :::.*****:*******.****:******:* *:::: . . ::::.:*:** :**.**:** :. ::**.:* .* *. * *:: : . :: ::* :*:::::.***.: :. : **: :*.*. *.::*:**:**: :*::: *.**.* :: . * : . ..**:*:*:::: . .*: . : :. *:.:. . : : :: . :.* .:* . .: .: :: : .* ..: :.: :: : *::: . :: :. :* . : :: . . .. . * . *.: .:.:.: *. : . .. . .. . :... * ..* *****.*:***.::***:**:*******.* ***:*:..* : ", "identical_positions": 143, "similar_positions": 329, "identity": "14.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-136", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K201-1", "uniprot_id": "KCT2_MOUSE", "id": "Q8K201-1", "name": "Keratinocyte-associated transmembrane protein 2", "aln": "---------------------------------------------------------------------MAASALGRMCGAAREKLS-----------------------------------------------------PGPGARGLGALARSLVLALLLVPVLCS---DRSENPPN---NATVSSP-VVVTAPGNHTSPSVS------------------------------------------------------------QISTTLSP-ASAEKSGSSSAAPTPTAAPSAPEEEADSNEDPSMEEEDLLALNSSPATGKDTLDNGDYGEPDYDWTTNPR----------------------------------------------------------------------------------------DEEPEDINIAISKES--------------------RRFRGFQDSVEVVKLPPPNRE---------DSHFFFHLLIFAFCAAVVYVTYHNKRKIFLLVQSRKWRDGLCSKTVEYHRLDQNVNEAMPSLKITNDYIF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NC54-1", "uniprot_id": "KCT2_HUMAN", "id": "Q8NC54-1", "name": "Keratinocyte-associated transmembrane protein 2", "aln": "---------------------------------------------------------------------MAAAVPKRMRGPAQAKLL-----------------------------------------------------PGSAIQALVGLARPLVLALLLVSAALSSVVSRTDSPSPTVLNSHISTPNVNALTHENQTKPSIS------------------------------------------------------------QISTTLPPTTSTKKSGGASVVPHPSPTPLS-QEEADNNEDPSIEEEDLLMLNSSPSTAKDTLDNGDYGEPDYDWTTGPR----------------------------------------------------------------------------------------DDDESDD---TLEEN--------------------RGYMEIEQSVKSFKMPSSNIEE-------EDSHFFFHLIIFAFCIAVVYITYHNKRKIFLLVQSRKWRDGLCSKTVEYHRLDQNVNEAMPSLKITNDYIF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EY36-1", "uniprot_id": "E7EY36_DANRE", "id": "E7EY36-1", "name": "", "aln": "MAAVRQTPLEDSTMVKVLVLVSMLVFSVSCASLPIADGEPPATVDSKEVKAPDTQNSSDLSSPIDSTLSQSAEVLGDDSAPAVEGKNSNKSVDVPTAPIANKDTEPQDNDPKKQKNNTENLKSDTGKQKNDLKLETDPKQPKTDLNQLETEPKQLETELKQPETEPKQLETESKQPKTEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSDTEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQQLETEPKQQLETESKQPVTENKQLETENKQQNNDPVQKGDDSVQPKNDHKQQDNDPEHLKPSPAAPQPQNFTEYIAESTFLGPDLGFGDDTGNDEDDDGDDDDDEVVDENDVSNDVEVKGGSSWDDISSPEDSQGKKNYPQGYKTPPESSEINIYSTQDEDSHFFFHLVIIAFLVAIIYITYHNKRKLMLLAQSRRWRDGFCSRGVEYHRLDQNVHEAMPSLKMTNDYIF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . ..* * . . * .: * * . . .:..* :: .. . . ..*.*. * : * * . :.:: . . : . . * : *....* . :.* ..: .. .:* : . **. : * *: *:: .* .*. . :: : * *. . * ********:*:** *::*:*******::**.***:****:**: **********:*******:******", "identical_positions": 81, "similar_positions": 79, "identity": "14.31%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-145", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3SWT0-1", "uniprot_id": "PECA1_RAT", "id": "Q3SWT0-1", "name": "Platelet endothelial cell adhesion molecule", "aln": "----------MLLALLLTMLLYASLQAQENSFTINSIHMESRPSWEVSNGQKLTLQCLVDISTTSKSRPQHQVLFYKDDALVYNVSSSEHTESFVIPQSRVFHAGKYKCTVILNSKEKTTIEYQLTVNGVPMPEVTVDKKEVTEGGIVTVNCSMQEEKPPIYFKIEKVELGTKNVKLSREKTS-NMNFVLIEFPIEEQDHLLVFRCQAGVLSGIKMQTSEFIRSEYVTVQEFFSTPKFQIQPPEMIIEGNQLHIKCSVQVAHLAQEFPEIIIQKDKAIVATSKQSKEAVYSVMALVEHSGHYTCKVESNRISKASSILVNITELFPRPKLELSSSRLDQGEMLDLSCSVSGAP-------VANFTIQKEETVLSQYQNFSKIAEERDSGLYSCTAGIGKVVKRSNLVPVQVCEMLSKPRIFHDAKFEIIKGQIIGISCQSVNGTAPITYRLLRAKSNFQTVQKNSNDP----VTFTDKPTRDMEYQCIVDNCHSHPEVRSEILRVKVIAPVDEVTISILSGN-DVQSGDEMVLRCSVKEGTGPVTFQFYKEKEGRPFHEETVNDTQVFWHHEQTSKEQEGQYYCTAFNRAS-IVTSLRSGPLTVRVFLAPWKKGLIAVVVIGVVIAALIVAAKYYFLRKAKAKQKPVEMSRPAVPLLNSNSEKVSEPSVETNSHY---------------------------DSQNMDVEYTEVEVSS-LEPHQENGRLP---------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q08481-1", "uniprot_id": "PECA1_MOUSE", "id": "Q08481-1", "name": "Platelet endothelial cell adhesion molecule", "aln": "----------MLLALGLTLVLYASLQAEENSFTINSIHMESLPSWEVMNGQQLTLECLVDISTTSKSRSQHRVLFYKDDAMVYNVTSREHTESYVIPQARVFHSGKYKCTVMLNNKEKTTIEYEVKVHGVSKPKVTLDKKEVTEGGVVTVNCSLQEEKPPIFFKIEKLEVGTKFVKRRIDKTS-NENFVLMEFPIEAQDHVLVFRCQAGILSGFKLQESEPIRSEYVTVQESFSTPKFEIKPPGMIIEGDQLHIRCIVQVTHLVQEFTEIIIQKDKAIVATSKQSSEAVYSVMAMVEYSGHYTCKVESNRISKASSIMVNITELFPKPKLEFSSSRLDQGELLDLSCSVSGTP-------VANFTIQKEETVLSQYQNFSKIAEESDSGEYSCTAGIGKVVKRSGLVPIQVCEMLSKPSIFHDAKSEIIKGHAIGISCQSENGTAPITYHLMKAKSDFQTLEVTSNDP----ATFTDKPTRDMEYQCRADNCHSHPAVFSEILRVRVIAPVDEVVISILSSN-EVQSGSEMVLRCSVKEGTSPITFQFYKEKEDRPFHQAVVNDTQAFWHNKQASKKQEGQYYCTASNRASSMRTSPRSSTLAVRVFLAPWKKGLIAVVVIGVVIATLIVAAKCYFLRKAKAKQKPVEMSRPAAPLLNSNSEKISEPSVEANSHYGYDDVSGNDA---------VKPINQNKDPQNMDVEYTEVEVSS-LEPHQALGTRATETVYSEIRKVDPN----------------LMENRYSRTEGSLNGT-----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P16284-1", "uniprot_id": "PECA1_HUMAN", "id": "P16284-1", "name": "Platelet endothelial cell adhesion molecule", "aln": "MQPRWAQGATMWLGVLLTLLLCSSLEGQENSFTINSVDMKSLPDWTVQNGKNLTLQCFADVSTTSHVKPQHQMLFYKDDVLFYNISSMKSTESYFIPEVRIYDSGTYKCTVIVNNKEKTTAEYQVLVEGVPSPRVTLDKKEAIQGGIVRVNCSVPEEKAPIHFTIEKLELNEKMVKLKREKNSRDQNFVILEFPVEEQDRVLSFRCQARIISGIHMQTSESTKSELVTVTESFSTPKFHISPTGMIMEGAQLHIKCTIQVTHLAQEFPEIIIQKDKAIVAHNRHGNKAVYSVMAMVEHSGNYTCKVESSRISKVSSIVVNITELFSKPELESSFTHLDQGERLNLSCSIPGAP-------PANFTIQKEDTIVSQTQDFTKIASKSDSGTYICTAGIDKVVKKSNTVQIVVCEMLSQPRISYDAQFEVIKGQTIEVRCESISGTLPISYQLLKTSKVLENSTKNSNDP----AVFKDNPTEDVEYQCVADNCHSHAKMLSEVLRVKVIAPVDEVQISILSSK-VVESGEDIVLQCAVNEGSGPITYKFYREKEGKPFYQMTSNATQAFWTKQKASKEQEGEYYCTAFNRANHASSVPRSKILTVRVILAPWKKGLIAVVIIGVIIALLIIAAKCYFLRKAKAKQMPVEMSRPAVPLLNSNNEKMSDPNMEANSHYGHNDDVRNHA---------MKPINDNKEPLNSDVQYTEVQVSS-AESHKDLGKKDTETVYSEVRKAVPD----------------AVESRYSRTEGSLDGT-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TIM5-1", "uniprot_id": "A0AB32TIM5_DANRE", "id": "A0AB32TIM5-1", "name": "", "aln": "--MQVKKQLTLRAGTFLILFLFTSDKAN-TEFIIKSVNLFIQPRNEVQRGTNVSLICQAEVSQSPGSNPNYEYIFYKDYEMLLTEKTTATHWFYSIPDARVFHSGKYECAVVIGHQNKKSGSTDLTVKGLLTPVLSVDQQRLKEGDNVTAVCTAEGEMGSLMFSFR-----DGPVELYRKSTNTQKVEQKLAFEHKRMRTVNMF-CYYSISLGSKIEISNNSNVIDIDIQELGITPEINVMPSANVIEGDLLTFSCNVDMTYQKNSELRISLVHGHTTLGLN--MGQKTYNMSAKANDSGQYECIASLGAIHKSSSVNITVNQLFSVPALSIHPPEVFEGEHFDITCHTDIIASVRIQREDIKYFIYKEKTLVISNYRYSNTARNVTNGKYMCVAKANGIIKESSNVLFRAKVLVSQPEIRVDAPPVIVD-KHFWIHCHSQNGSLPIIYTLKRNNITVNRTEVSNPHEKARFIAMISAPSDISSYFCEAENNGKISVKMSQRLNETVIVPVGKPLFTVIPIPGNIEEGEDVTLICGIPKGSPPINFSFYG-NSHTPINTTTVQSNSSSFVLSAVSRQKSGNYYCEAFNLAN---KLSKSDIISIEVSLAKWKKILTVAFCLLILALVVIFIVLRYKAKRGRETYNPPASQAAHMPDLMPAFPKSDDFLIHESHYSGFSVGVNNKESVWSEKPPDISDEGILQLPNEGDVEYTEVVHSQPLDPTRIPLRKGTDTVYSELQTQGSPDHINHACWNMLNSTMIFLHQWTSSSQTSPFGILPLPYQSLPSVRNTHSSSKTLISHVFNFV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * :.* :* :.: ..* *:*:.: * * .* :::* * .::* :. ..::. :**** :. . .: : **: *::.:*.*:*:*::. ::*.: . :: *.*: * :::*::. :*. * . *: * .: *.:. *: .... : : * : : * * : * ::: *: . : : * **::.: *. ::** * : * ::::: :. .* : :.:: :. . : .*.: * .: **:* * .. . * * **: :.:.:**. * *. ..: :** ::::* . :: * **.*:: . ::: * : .* * *.* . ::*.*. * . . ::*:* * ** ::. : : : *.* .*: ** * * : . .: .. . .: . *: .* * .:* . . *: *. **.**.: ::::. ::.*.::.* *.: :*: *:.:.** :. *: . : .. : . .*:::.*:*** * * *. . :* :::.* ** *** * ... : :: :*. . * ::.: . * . . * * . * .: :. . : . : **:**** *. :. : ", "identical_positions": 136, "similar_positions": 262, "identity": "16.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-146", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F7FLU1-1", "uniprot_id": "F7FLU1_RAT", "id": "F7FLU1-1", "name": "", "aln": "--------------MNPPMASQE----------------RVDAVANGTGFHRCRKQAAYTPGTCELLRVMMKESKLTNFQQRHIMDTMKRGAPLPLQCNPTSSQRGSPSKKSAAAIYLPPILATHTHLRPASLCQANGAYSREQFKPQATRDLE--KEKRRLQNIFATGKDMEERK-KVPHVQQEDPAPELDRFDELVKEIQDRKEFLAAMEALGQGKQYRGIILAEISQKLREMEDIDRRRSKELRKALTTT----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D9S1-1", "uniprot_id": "EVG1_MOUSE", "id": "Q9D9S1-1", "name": "UPF0193 protein EVG1 homolog", "aln": "------------------MASQE----------------RVDSVTKGTGFRRCRKQAGYTPGTCELLRVMMKESKLTNFQQRHIMDTMKRGAPLPLQCNPTSSLRGSPSKKAASAIYLPPILATHSHLRPASLCQANGAYSREQFKPQATRDLE--KEKRRLQNIFATGKDKEERK-KVPHVRQEDPAPELDRFDELVKEIQDRKEFLAAMEALGQGRQYRSIILAEISQKLREMEDIDRRRSKELRKALATT----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BZE7-1", "uniprot_id": "EVG1_HUMAN", "id": "Q9BZE7-1", "name": "UPF0193 protein EVG1", "aln": "------------------MASQK----------------QMEVVTKGTGFRRRPKTITYTPGTCELLRVMMKESKLTNIQQRHIMDIMKRGDALPLQCSPTSSQRVLPSKQIASPIYLPPILAARPHLRPANMCQANGAYSREQFKPQATRDLE--KEKQRLQNIFATGKDMEERKRKAPPARQKAPAPELDRFEELVKEIQERKEFLADMEALGQGKQYRGIILAEISQKLREMEDIDHRRSEELRKGLATT----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F0P7-1", "uniprot_id": "E7F0P7_DANRE", "id": "E7F0P7-1", "name": "", "aln": "-----------------MMAS-------------------------GSKYKESG-IPQYRTDTRQLIKLMMQESRLTDFQQRQINNKLKNGGALPITFYSSPLEPNTPSETRVTRVGT---LVGQQQKRSAERCRAGDNYKREQFLPSAARDLE--KEKRKLQNLLSTGQ-KDAGPTHSQRESTERREQPVDRFQEVLDEIEDRRQFLEEMMSLGKGHQYQQLINTEISQKICELEEIDKKRSEELRTPQLTGKEEQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VSS7-1", "uniprot_id": "EVG1_DROME", "id": "Q9VSS7-1", "name": "UPF0193 protein EVG1 homolog", "aln": "MSRHRFNNVQIKALPGGLMAHHEPDADGGQPGSQKLPMWPSERIPPGGAGAFHSAKVQYSKETADLIRLLVKESKMSMLVRKQIDESLRNGEPLPLPEPPRPNTNNDPDKETLAILDR----ARNAKRKNLRQIEASGAYKQSYYRPPADNRMHGEKAKSQLQFTMAGTHLPDPAIKPRRRPREEQLVTEEDLINELLDQINERAEWLTEMESMGQGKKYRPEIRDQIAERLRRIQALESKMKMKSNGGFRFVD---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** * * * :*::::::**::: : :::* : ::.* .**: . . *.: : : . . : : .*.. *.:. : * * . :. * * :** :: : : : * ::*::.:*::* ::* * ::*:*::*: * :*:::: .:: :: : . : . ", "identical_positions": 32, "similar_positions": 76, "identity": "12.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-149", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZYA2-1", "uniprot_id": "D3ZYA2_RAT", "id": "D3ZYA2-1", "name": "", "aln": "MAQVDSQERWTKV----ALGGMIRDSQTLSVNLESEEEDGR--------------EGGSPVTQNNTDLQFDTQSCKEEDNWSECFRAGCVEQRPGKIPRKTNNWGGRGWRITQTQDSPGLQEALGAPSRSFLYKVQ--MQPLRD--SVGSDRVKKENKDPASEALTSFLDTGGSFGTQNSLEASSLDKNSLEHFPRFES----------TPAQTSSIPAGLAA-GLVKAQGSRKAQGQVGPEGSRQEEEGPDRCVQGRRAFQKSSELQVSAEQRG--IKPYVCQLCGKAYSHRSTLQQHRRLHTGERPYRCPFCDKAYTWSSDHRKHIRTHTGEKPYGCPDCGRAFVRSSDLRKHQRNMHSNDKPFPCAQCGLTFNRPLSLLRHQRTHLGAKPFRCSCCSREFSVASRMVEHQRVHSGERPFPCSICGKCFTKSSNLHEHQTLHTGQRPFKCADCGVTFAQPSRLLRHQRIHTGERPFPCAECGQAFARSSTLKRHQQTHSGDKDFLCAECGRAFRIASELAQHIRMHNGERPYQCEGCGQTFTRSSHLQRHQAKHDTCK-EPVPSSSDE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z0W3-1", "uniprot_id": "D3Z0W3_MOUSE", "id": "D3Z0W3-1", "name": "", "aln": "MAQVDSQDRWTKV----PLG----STQMLRMSLESEEEDGR--------------KGGSPGTQNNTDSQFDTQSCKEEENWPECFSAGCVAQKPGEMPGKTSNGGKKASRITQIRDSPKLQEALGAPSRSLLHKVQ--IQPLRD--SVGSDGGKKANKDPASEVPNSFLDSGGYFEAQNSVEASSLDKNSLEHFPRSES----------TLVQTPTIPASL----LVKVRSSRKVQGQAGPEGSGQEEEGLDRCVR---AFQKSTKVQVPAEHHG--SKPYVCQLCGKAYSHRSTLQQHRRLHTGERPYRCPFCDKAYTWSSDHRKHIRTHTGEKPYGCPDCGRAFVRSSDLRKHQRNMHSNDKPFPCAQCGLTFNRPLSLLRHQRTHLGAKPFRCSSCGREFSVASRMVEHQRVHSGERPFPCSTCGKCFTKSSNLQEHQTLHTGQRPFKCTDCGVTFAQPSRLLRHQRIHTGERPFPCAECGQAFARSSTLKRHQQIHSGDKDFLCAECGRAFRIASELAQHIRMHNGERPYQCEGCGQTFTRSSHLQRHQAKHDTCKKEPVPSSSDE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T619-1", "uniprot_id": "ZN648_HUMAN", "id": "Q5T619-1", "name": "Zinc finger protein 648", "aln": "MAQVDSQDRWGEASPLSSLTEEAHDTQMLSMNLESDDEDGGEAEKEGTADPVACPRGSSPVTHENPDLPWPHPLGKEEEKFSDSSSAGGMGQKPVEMSGKAS-WSRDVTKINETQGSPGASRALGSLPSGLAHKLLGQMQPLGDRLPAGDDGYSGANQDAVLDVPPSFPSNGKYLCAHKSVDTSAGN-SSLLCFPRPGSNWDLPTQETHTPAQASATPASLAAAVLAKARNSRKVQNQAGRREGGEAEARPYRCLRGGRAFQKPSKPLSPAETRGGAAKRYACELCGKAYSHRGTLQQHRRLHTGERPYQCSFCDKAYTWSSDHRKHIRTHTGEKPYPCPDCGKAFVRSSDLRKHQRNMHSNNKPFPCSECGLTFNKPLSLLRHQRTHLGAKPFRCPACDREFAVASRMVEHQRVHSGERPFPCPTCGKCFTKSSNLSEHQTLHTGQRPFKCADCGVAFAQPSRLVRHQRIHTGERPFPCTQCGQAFARSSTLKRHQQIHSGEKGFLCAECGRAFRIASELAQHIRMHNGERPYQCEDCGQAFTRSNHLQRHRAKHGTCKKEPIPSSSDE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q0F5-1", "uniprot_id": "A0A8M9Q0F5_DANRE", "id": "A0A8M9Q0F5-1", "name": "", "aln": "MAKMN--NLWNTEAFTDNAYISKRSIRKILIRKRHYLPAEN--------------KISDPNNKINPVLPIEKNINASTSCVEEITVQELGSQISSTQFYIPAKYSEQCCGTDRELDEKEIETGSGSDPSSQLNHKD-----------SEPTSIPHVKVKEEVDITKACGLAGIQPETEAEEDECDVEGNTDDTPKSPEN-------------------------QLLKSQLMFATMKKRGMEG--DTENRPYKCTYCNWAFKKSSNLLSHIDTHRG-LKPHVCDLCGKAYSHQGTLQQHKRLHTGERPYQCPFCEKSYIWSSDFRKHIRTHTGEKPYICEECGKDFVRSSDLRKHERNMHTNNKPFLCKHCGKTFNKPLSLHRHERTHLGERPFICPDCGKAFALASRMTEHRKIHSGVRPYTCTVCSKSFTKSSNLAEHLTVHSGVRPHKCSECGVAFAMASRLVRHQRIHKAEQSYPCQDCDLSFSHITALKKHQKKHTEGMIFVCGQCSKSFHQEFLLKEHMQSH-------------------------ADTETCIA---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**::: : * . : : : . . ..* .: *. . . : * . . . . .. . . *: . . : : . : : * :. . : . : .: . * * : . : * . : * :* **:*.:: : : * :.*:********:.*****:*********:*.**:*:* ****.************* * :**: **********:****:*:*** * .** ***:**** **:***** :** *. *.: *::****.**:::*** **:.*. *.*.******* ** *:*:* **.**::***:** .***:******..*:.:** :*. :*:: ::**:**: *: *:*.:*.::*: * :*:: * *. ** ", "identical_positions": 169, "similar_positions": 123, "identity": "29.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-153", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B2RYH9-1", "uniprot_id": "S71A2_RAT", "id": "B2RYH9-1", "name": "Solute carrier family 71 member 2", "aln": "MSTDGESPEEPGWKAVASPKASAMPEKRGSAQAASSSWLQGFGQPSVYHAAFVIFFEFFAWGLLTTPMLTVLHETFPQHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKPFLLGTVFFTCFPIPLMRISPWWYFGMISVSGVFSVTFSVIFAYVADFTQEHERSTAYGWVSATFAASLVSSPAIGTYLSSNYGDSLVVLVATVVALLDICFILVAVPESLPEKIRPASWGA-------------------------------------------------------------------------QISWKQADPFASLKKVGKDSTVLLICITVFLSYLPEAGQYSSFFLYLRQVIGFGSVKIVAFIAMVGILSILAQTVFLSKLMRSLGNKNTVLLGLGFQILQLAWYGFGAQAWMMWAAGTVAAMSSITFPAVSALISRNAESDQQGVAQGIITGIRGLCNGLGPALYGFIFYLFHVELNELGPKLDS---DNDPLQGAFIPGPPFLFGACIVLMSFLVALFIP-------EYRKTGGVQKHNNSISGSLSTPPERGSDEDIEPLLQDSNIWELS-SEEPGNQCTEL----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIA9-1", "uniprot_id": "S71A2_MOUSE", "id": "Q8CIA9-1", "name": "Solute carrier family 71 member 2", "aln": "MSTDGESPEEPRWKAVASPKASTMPEKRGSAQAASGSWLQGFGHPSVYHAAFVIFLEFFAWGLLTTPMLTVLHETFPQHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKPFLLGTVFFTCFPIPLMRINPWWYFGMISVSGVFSVTFSVIFAYVADFTQEHERSTAYGWVSATFAASLVSSPAIGTYLSANYGDSLVVLVATLVALLDICFILIAVPESLSEKIRPASWGA-------------------------------------------------------------------------QISWKQADPFASLKKVGKDSTVLLICITVFLSYLPEAGQYSSFFLYLRQVIGFGSVKIVAFIAMVGILSIVAQTVFLSKLMRSLGNKNTVLLGLGFQMLQLAWYGFGSQAWMMWAAGTVAAMSSITFPAVSALISRNAESDQQGVAQGIVTGIRGLCNGLGPALYGFIFYMFHVELSELGPKLNS---DDDPLQGAFIPGPPFLFGACIVLMSFLVALFIP-------EYRKTSGVQKHNNSTSGSLSTPPERGSDEDIEPLLQDSSIWELS-FEEPGNQCTEL----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5SR56-1", "uniprot_id": "S71A2_HUMAN", "id": "Q5SR56-1", "name": "Solute carrier family 71 member 2", "aln": "MSVE--PPPELEEKAASEPEAGAMPEKRAGAQAAGSTWLQGFGRPSVYHAAIVIFLEFFAWGLLTTPMLTVLHETFSQHTFLMNGLIQGVKGLLSFLSAPLIGALSDVWGRKPFLLGTVFFTCFPIPLMRISPWWYFAMISVSGVFSVTFSVIFAYVADVTQEHERSTAYGWVSATFAASLVSSPAIGAYLSASYGDSLVVLVATVVALLDICFILVAVPESLPEKMRPVSWGA-------------------------------------------------------------------------QISWKQADPFASLKKVGKDSTVLLICITVFLSYLPEAGQYSSFFLYLRQVIGFGSVKIAAFIAMVGILSIVAQTAFLSILMRSLGNKNTVLLGLGFQMLQLAWYGFGSQAWMMWAAGTVAAMSSITFPAISALVSRNAESDQQGVAQGIITGIRGLCNGLGPALYGFIFYMFHVELTELGPKLNS---NNVPLQGAVIPGPPFLFGACIVLMSFLVALFIP-------EYSKASGVQKHSNSSSGSLTNTPERGSDEDIEPLLQDSSIWELSSFEEPGNQCTEL----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RM35-1", "uniprot_id": "A0A8M1RM35_DANRE", "id": "A0A8M1RM35-1", "name": "", "aln": "-----------------------MLIKYMRQRSVG--------RAKVAHAVVVIFMEFFAWGLLTTPMLTVLHDTFPQHTFLMNGLIQGVKGLLSFMSAPLVGALSDVWGRKSFLLLTVFFTCAPIPLMRISPWWFFALMSVSGLFSVTFSVIFAYVADITEEHERSTAYGLVSATFAASLVTSPAIGAFLSIHYGDSLVVLLATIIAVLDILFVLLVVPESLPDKMRLSSWGF-------------------------------------------------------------------------PISWEQADPFASLRKVGKDSTVLLICVTVLLSYLPEAGQYSSFFLYLGQVINFSSAAIAGFIAMVGILSIGAQTLLLSVLMKKIGNKSTVLLGLGFQLFQLAWYGFGSEPWMMWAAGAVAALSSITFPAISALVSRCTDRDQQGAVQGIITGIRGLCNGLGPFLFGFIFFLFNVELNDISTVQSNSAVTPDTKQKSVVPGPPFVFGACTVVLALLVAVFIPSQPAPLVKTCSSSSTCVVTEPMSSILAGGSLPASDEDIEPLLQDSSL--------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPD8-1", "uniprot_id": "Q9VPD8_DROME", "id": "Q9VPD8-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "-----------------------MSKFGLKKLLVSLASTSGIGKPSVGHILVVVFLEYFAWGLLTMPMIATLKETFPDHTFLMNGLVMGVKGILSFLSSPLIGALSDIYGRKVLLLITVIFTSLPIPMMTMDNWWFFVISSISGVLGVSFSVAFAYVADVTTKEERSRSYELVSATFAASLVIAPAMGNLIMDRYGINTVVLVATLVSTTNVMFVLLAVPETLQQNVRST-----------------------------------------------------------------------------GLSWKQADPFLSLRRVGSDPNVLLLCVVMFTFLLPEAGEYSSVPAYLKLTMGFDFTELSTLVAFMAILGISIN-VTLGSIVKTLGAKNAIILGLLLELLQLILFAIGYEKWQMWLAGNVAALSSITFPAVSAYVSLYTDVETQGAVQGMITGMSGLCSGLGPALFGIVFYLSDMDLDKNRILIGS-------VSGDRTVTNPFMIGAISVFIGILLASYIP------------------DEKVSR--GRREEFSALKYIIEMEEATTI--------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPE0-1", "uniprot_id": "Q9VPE0_DROME", "id": "Q9VPE0-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "----------------------MAQLKFLRPLVKVLVNRSGIGKASVWHAVIVTFMHYFSWGLLTVPFIEKLSGSFGNRVLLVDGLVYGVRGILGFVTTPVMGAISDFHGRKVVMLLAVATTYAPIPFMMLKSWWFFAILTVSSICGSTYSSSLAYVADTTTVENRSKGYGIVAASFGAGIAFSPSLGNYLMKSYGSASVILIAAITGLINIMFIIFAVPESLVLKEKNNMLDEESDN-----KMEDINPKERKEILNREEKLNNHVSANKSNHGTSQNLVTNKELGQQFNKEENLQNDLTEKEKIDNGSLNSSDLWEVLRKSRKDKNLLVIYLITFLSIWPFAGVDSTAPVYLKTNMGFEYEEVSMMLGLLSVLAITSN-LLLGYIINIVGAKWSIRLGLLLLLLQLFFFGFGTHHWMYWLSSILAALATIIPAANNAVASIYASPDNRGAVLGIISGIECLSEGVGPAFFGVLFFIFQDDSKN--KVNSP-------------ISMPFVISAIGVFVAIVLTGFIK----------------KETVEKAPLIYKIIDDASEDEVEPLAKTTFKYEKNNGYVKLEIDDNYDSDCKEHSFK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPD9-1", "uniprot_id": "Q9VPD9_DROME", "id": "Q9VPD9-1", "name": "Major facilitator superfamily (MFS) profile domain-containing protein", "aln": "----------------------MAQLKFLRPLVKVLVNRSGIGKASVWHAVIVTFMHYFSWGLLTVPFIEKLSGSFGNRVLLVDGLVYGVRGILGFVTTPVMGAISDFHGRKVVMLLAVATTYAPIPFMMLKSWWFFAILTVSSICGSTYSSSLAYVADTTTVENRSKGYGFVAASFGAGIAFSPSLGNYLMKSYGSASVILIATITGMINILFIIFAVPESLVLKEKKVILNENNDNKVEDTKVDDISPKEKKENLNGEGKVN--VEVNKP---TSQNIVTNKELDQQFSKEENLQNDLTEKEKIDNGSLNSSDLWEVLRKSRKDKNLLVIYLITFLSIWPFAGVDSTAPVYLKTNMGFEYEEVSMMLGLLSVLAITSN-ILLGYIMNIVGAKWSIRLGLLLLFLQMLFFGFGTHHWMYWLSSILAALATIIPAANNAVASIYASPDNRGAVLGIISGIECLSEGVGPAFFGLLFFIFQDDSETDLKVNSP-------------ISMPFVISAISVFVAIVLSSFIK----------------KDTLGNE-------ETRVANENIP---------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :..* * .* *:.:*:***** *:: * :* ::.:*::**: **:*:*.*:::*::**:**. *** .:* :* * ***:* :. **:* : ::*.: . ::* :***** * .:** .* *:*:*.*.:. :*::* : ** *:*:*:: . :: *::..***:* : : * :.:* : *:: .* .:*:: : : * ** *: ** :.* : ::.::.:*.* : *. ::. :* * :: *** : ::*: :.:* . * * :. :**:::* .* .* * :. : :*.. *:::*: *..*:** ::*.:*:: . : . **::.* *.:.:::: :* . ", "identical_positions": 110, "similar_positions": 154, "identity": "18.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-154", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZFA0-1", "uniprot_id": "D3ZFA0_RAT", "id": "D3ZFA0-1", "name": "", "aln": "MARISLLLLLLLSLPQQLSSLPWP--DTAQG--TMAGLILTALEKATLFLEDRLPKINLDGAVGFQVLEVQLRGVQEKWAHNPLLQPLSLRAG--QLANTLFALLQNSIFYLKQSDPTYLREFQPSLQPGFWKLPHAWTRTNASLVYPWLEPLDSFSEESSDACLVQLLGTGTDSRQPCRLSDFCRTLMTKAGCSGYSLSHQLLFFLWARMQGCT---EGLFLQS------QHYIDIFCANMMDLNRRAEAMGYAYPTQDLFMENIMFCGMAGFSDFYKLHWLEAILNWQNPQVGCFGKPDTKGE--PPEVPHRQGVLRRVRRREKLFEDGCSCHNTATAVAALGGFLYILAEYHPDNG-----------EPTPPT-----RSPASNYQDGAASPDAQRIGRPLSISS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UST5-1", "uniprot_id": "CP089_MOUSE", "id": "Q3UST5-1", "name": "UPF0764 protein C16orf89 homolog", "aln": "MARLGLLLLLLLALPPHFSSVSWP--DTAQG--TMANLILTALEKATLFLEDRLPTINLDGVVGFQVLEVQLRGVQEKWAHKPLLQPLSMRAG--QMANTLSALLQKSIFYLKQSDPTYLREFQPSIQPGFWKLPNDWTRTNASLVYPWLEPLDSFSEESSDVCLVQLLGTGTDSSQPCRLSNFCRTLMTKAGCSGYSLSHQLLFFLWARMQGCT---EGLFLQS------QHYMDIFCANMMELNHRAEAVGYAYPTQDLFMENIMFCGMAGFSDFYKLRWLEAILSWQNPQVGCFGRPDTKGE--PSEVPHQQGILRRVRRREKLFADGCSCHNTATAVAALGGFLYILAEYHPDNGDAHPEYYPNHGDPYSSS-----QSPASNYQDGAAGPDVQRTGRPLSVS------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UX73-1", "uniprot_id": "CP089_HUMAN", "id": "Q6UX73-1", "name": "UPF0764 protein C16orf89", "aln": "MASLGLLLLLLLTALPPLWSSSLPGLDTAESKATIADLILSALERATVFLEQRLPEINLDGMVGVRVLEEQLKSVREKWAQEPLLQPLSLRVG--MLGEKLEAAIQRSLHYLKLSDPKYLREFQLTLQPGFWKLPHAWIHTDASLVYPTFGPQDSFSEERSDVCLVQLLGTGTDSSEPCGLSDLCRSLMTKPGCSGYCLSHQLLFFLWARMRGCT---QGPLQQS------QDYINLFCANMMDLNRRAEAIGYAYPTRDIFMENIMFCGMGGFSDFYKLRWLEAILSWQKQQEGCFGEPDAEDEELSKAIQYQQHFSRRVKRREKQFPDSRSVAQAGVQWRNLGSLQPLPPGFKQFSCLILPSSWDYRSVPPYLANFYIFLVETGFHHVAHAGLELLISRDPPTSGSQSVGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A7MCS3-1", "uniprot_id": "CP089_DANRE", "id": "A7MCS3-1", "name": "UPF0764 protein C16orf89 homolog", "aln": "MKSLKMLYPLFMLLVLS-SKIDLSNQDVIDN-------ILMSLSKGITYFDMQGSNINLDGVVGYIILQAQLREATRTWPHSDFLS-LSQRAAAISMLKRLSKSLSTAASTLQETDPKYFKEFEPILDSSFWSLPGEWSSTDPSLVYTSVRAMECYDEHMSDKCMTFLLGTWKDNGTPCIVTKTCRDTMTQFGCPHYSLSHQLLYFMIGTMKGCSKMLKGDLRLSRVNITVGHYKRIFCSNMMKSNQDIFKNSLTGQMQDIFIENILLCGLVGFSDFYKLDWLQSILTWQDQEAGCFGKEEDISH---IFEEFLDAPHKRVKRREKTLTDGCSSHMTGVAVSALGGFLNFYLS------------------------------------------EQDITKRPII--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : :* *:: . . *. :. ** :*.:. ::: : . ***** ** :*: **: . ..*.:. :*. ** *.. : : * :. : *: :**.*::**: ::..**.** * *:.****. . . :.:.*. ** *:. **** .*. ** ::. ** **: **. *.******:*: . *:**: :* : * .* :**:***. *: . : :*:*:***::**: ******** **::**.**. : ****. : .. . : :**:**** : *. * :.. **.: : : * ", "identical_positions": 112, "similar_positions": 109, "identity": "27.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-155", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61957-1", "uniprot_id": "SUMO2_MOUSE", "id": "P61957-1", "name": "Small ubiquitin-related modifier 2", "aln": "MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P61956-1", "uniprot_id": "SUMO2_HUMAN", "id": "P61956-1", "name": "Small ubiquitin-related modifier 2", "aln": "MADEKPKEGVKTENNDHINLKVAGQDGSVVQFKIKRHTPLSKLMKAYCERQGLSMRQIRFRFDGQPINETDTPAQLEMEDEDTIDVFQQQTGGVY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IE38-1", "uniprot_id": "A0A0R4IE38_DANRE", "id": "A0A0R4IE38-1", "name": "Small ubiquitin-related modifier", "aln": "MADEKTKDGVKSEKS-HINLRVSSQDGSVVQFKIKKHAPLSKLMKVYCDRQGLTRKLIRFMFDGESIKETDTPALLEMEDEDAIEVFQEQLAGLI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****.*:***:*:. ****:*:.***********:*:*******.**:****: : *** ***:.*:****** *******:*:***:* .*: ", "identical_positions": 66, "similar_positions": 22, "identity": "69.47%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-166", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L536-1", "uniprot_id": "A0ABK0L536_RAT", "id": "A0ABK0L536-1", "name": "Leucine-rich repeat-containing protein 2", "aln": "------MGHKVVVFDISVVRALWETRVKKHKAWQKKEAERLEKSALEKIKEEWEFVAECRRKGVPQAEYCKNGFVDTSTRLLERIERNSVARQSARVKDRGKRSNPFVFELSGTQWKELPDSLKEQTHLKEWHIHNTLIQIIPTYIELFHSMKILDLPKNQITCLPPEIGRLKNLKELNVSFNHLKSIPPELGDCENLERLDCSGNLDLMELPFELSNLKQVTFVDISANKFSSVPICVLRMCRLQWLDISSNDLTDLPQDIDRLEELQGFLLYKNKLTYLPQAMLNLKKLTLLVVSGDDLVELPTALCDASTPLKFVSLLDNPIDKTRCQDTDDTVESEQDRQHFDKEFMKAYIEDLKER-AVPSYTAKVSFSLQL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VDB8-1", "uniprot_id": "LRRC2_MOUSE", "id": "Q8VDB8-1", "name": "Leucine-rich repeat-containing protein 2", "aln": "------MGHKVVVFDISVVRALWETRVKKHKAWQKKEAERLEKSALEKIKEEWDFVAQCRRKGVPQAEYCKNGFVDTSTRLLEKIERNSVSRQSARVKDRDKRRSPFVFELSGTQWKELPDSLKEQTHLKEWYIHSTLIQIIPTYIELFQAMKILDLPKNQITCLPAEIGRLKNLKELNVSFNHLKSIPPELGDCEHLERLDCSGNLDLMDLPFELSNLKQVTFVDISANKFSSVPICVLRMCRLQWLDISSNNLSDLPQDIDRLEELQGFLLYKNKLTYLPQAMLNLKKLTLLVVSGDHLVEVPTALCDASTPLKFVSLVDNPIDKTGCQDTEDTVESERDRQHFDKEFMKAYIEDLKEREAVPSYTTKVSFSLQL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYS8-1", "uniprot_id": "LRRC2_HUMAN", "id": "Q9BYS8-1", "name": "Leucine-rich repeat-containing protein 2", "aln": "------MGHKVVVFDISVIRALWETRVKKHKAWQKKEVERLEKSALEKIKEEWNFVAECRRKGIPQAVYCKNGFIDTSVRLLDKIERNTLTRQSSLPKDRGKRSSAFVFELSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLRMSNLQWLDISSNNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKKLTLLVVSGDHLVELPTALCDSSTPLKFVSLMDNPIDNAQCEDGNEIMESERDRQHFDKEVMKAYIEDLKERESVPSYTTKVSFSLQL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TWD1-1", "uniprot_id": "A0AB32TWD1_DANRE", "id": "A0AB32TWD1-1", "name": "", "aln": "MMKAERVAVDIPVYDLSLIRELWEGRVKKHRQRQKKEEERISKSALARVNQQWQYRIACKK--------LKS---TEVTALHTYLERSTLQELHTHTSDSDSESSKLIFELNGQKWMKLPEDLQFMTFLREWHIHGTRIPEIPSYIEAFVELRVLDVPKNGLSRLPVEIGKLLNLRELNVNYNKLLSIPAELGECVNLEHLEMTANTHLAELPFELSNLKKLQHLDLAENKFPSIPICVLRMESLKCLDISNNALRDLPEDIDRLEALEMLFLHRNAVRYVPMSTNNLLHLKMLVISADQLYSLPSHLVDNPK-IKLIRLYDNPIK---AEDEEEMNMDAEAQDTHEKEFMKTYIESLQDRDTQPSYTTKVSLSCLL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .: *:*:*::* *** *****: **** **:.**** :::::*:: *:: *. . * :**.:: . : .* ... . ::***.* :* :**:.*: *.*:**:* .* * **:**: * :::**:*** :: ** *** * **:****.:* * ***.***:* :**:*: :.* .* :*********:: .:*:: ***.*:******* *: ****.* * ***:****** *: ::*::* : *:* : ** :*.:**:*.*.* .:*: * * .. :*:: * ****. .:* :: . . :: .:**.**:***.*::* : ****:***:* *", "identical_positions": 158, "similar_positions": 117, "identity": "41.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-178", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A9I3-1", "uniprot_id": "FLOWR_RAT", "id": "D4A9I3-1", "name": "Calcium channel flower homolog", "aln": "MSGSV-AAGAAAGPVPPAQEE-GMTWWYRWLCRLAGVLGAVSCAISGLFNCVTIHPLN---IAAGVWMIMNAFILLLCEAPFCCQFVEFANTVAEKVDRLRSWQKAVFYCGMAIVPIVMSLTLTTLLGNAIAFATGVLYGLSALGKKGDAISYARIQQQRQQADEEKLAETFEGEL------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BG21-1", "uniprot_id": "FLOWR_MOUSE", "id": "Q8BG21-1", "name": "Calcium channel flower homolog", "aln": "MSGSG-AAGAAAGPAPPAQEE-GMTWWYRWLCRLAGVLGAVSCAISGLFNCVTIHPLN---IAAGVWMIMNAFILLLCEAPFCCQFVEFANTVAEKVDRLRSWQKAVFYCGMAIVPIVMSLTLTTLLGNAIAFATGVLYGLSALGKKGDAISYARIQQQRQQADEEKLAETFEGEL------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UGQ2-1", "uniprot_id": "FLOWR_HUMAN", "id": "Q9UGQ2-1", "name": "Calcium channel flower homolog", "aln": "MSSSGGAPGASASSAPPAQEE-GMTWWYRWLCRLSGVLGAVSCAISGLFNCITIHPLN---IAAGVWMIMNAFILLLCEAPFCCQFIEFANTVAEKVDRLRSWQKAVFYCGMAVVPIVISLTLTTLLGNAIAFATGVLYGLSALGKKGDAISYARIQQQRQQADEEKLAETLEGEL------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PQU8-1", "uniprot_id": "A0A8M9PQU8_DANRE", "id": "A0A8M9PQU8-1", "name": "", "aln": "MSTEE----AEAPTKTATDED-GMSWWYRWICKLAGVLGGISCATMGVWNCVTVHPLN---IAAGVWMVLTAFVLFLCEVPFCCQFVEFANAVAARADRLKPWQKALFYCGMALFPVFLSFSITTLVGNAIAFATGVLYGLASLGKKGDAVSYARLQHQKQ-GDEEKLAGTTEESVP-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q95T12-1", "uniprot_id": "FLOWR_DROME", "id": "Q95T12-1", "name": "Calcium channel flower", "aln": "MSFAEKITGLLARPNQQDPIGPEQPWYLKYGSRLLGIVAAFFAILFGLWNVFSIITLSVSCLVAGILQMVAGFVVMLLEAPCCFVCFGQVNEIAEKVESKPLYFRAGLYIAMAIPPIILCFGLASLFGSGLIFGTGVVYGMMALGKKASAEDMRAAAQQTFGGNTPAQTNDRAGIVNNAQPFSFTGAVGTDSNV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * . .*: :: .:* *::... . *::* .:: .*. :.**: :: .*:::* *.* * . .* :* :.: : :* :* .**: *:.:.: :::*.*..: *.***:**: :****..* . :* .: : : ", "identical_positions": 37, "similar_positions": 65, "identity": "19.07%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-180", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N461-1", "uniprot_id": "FXL16_HUMAN", "id": "Q8N461-1", "name": "F-box/LRR-repeat protein 16", "aln": "------MSSPGIDGDPKPPCLPRNGLVKLPGQPNGLGAASITKGTPATKNRPCQPP-PPPTLPPPSL---AAPLSRAALAGGPCTPAGGPASALAP-----GHPAERPPLATDEKILNGLFWYFSACEKCVLAQVCKAWRRVLYQPKFWAGLTPVLHAKELYNVLPGGEKEFVNLQGFAARGFEGFCLVGVSDLDICEFIDNYALSKKGVKAMSLKRSTITDAGLEVMLEQMQGVVRLELSGCNDFTEAGLWSSLSARITSLSVSDCINVADDAIAAISQLLPNLAELSLQAYHVTDTALAYFTARQGHSTHTLRLLSCWEITNHGVVNVVHSLPNLTALSLSGCSKVTDDGVELVAENLRKLRSLDLSWCPRITDMALEYVACDLHRLEELVLDRCVRITDTGLSYLSTMSSLRSLYLRWCCQVQDFGLKHLLALGSLRLLSLAGCPLLTTTGLSGLVQLQELEELELTNCPGATPELFKYFSQHLPRCLVIE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I3ITN3-1", "uniprot_id": "I3ITN3_DANRE", "id": "I3ITN3-1", "name": "F-box/LRR-repeat protein 16", "aln": "MKERLPMLNMSTPSDLKSPCMTRNGMVKLPPQPNRLGSASITKGTPAAKNRLCQSSSVPTILPPPSLPYHLDPLPTAASLLGPDLDTS-PVTAIKPPLRQFPKPLLERQLILDEKVLNRLLWYFTTAEKCILAQVCKTWRKVLYQPKFWEGVTPILHAKELYTILPNGEKEFVSLQAFALRGFQAFCLVGVSDLDICEFIDNYPLSKKGVKSVSLKRSTITDAGLEVMLEQMQGLMHLELSGCNDFTEAGLWSSLNARLTSLSVSDCINVADDAIAAISQLLPNLSELSLQAYHVTDTAMAYFTAKQGYTTHTLRLNSCWEITNHGVVNMVHSLPNLTSLSLSGCSKITDDGVELVAENLRKLRSLDLSWCPRITDMALEYIACDLHKLEELVLDRCVRITDTGLGYLSTMSTLRSLYLRWCCQVQDFGLQHLYGMRSLRLLSLAGCPLLTTTGLSGLIQLQDLEELELTNCPGATAELFKYYSQHLPRCMVIE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . .* *.**:.***:**** *** **:*********:*** **.. *. ****** **. ** ** :. *.:*: * :* . * ***:** *:***::.***:******:**:******** *:**:*******.:**.******.**.** ***:.******************.*******::*********************:::******************.**:**************************:*************:*****:**::****** ************:********:********:*********************************:*****:*****************.******:*****************:** .: *********************:***:*************.*****:*******:***", "identical_positions": 380, "similar_positions": 65, "identity": "76.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-181", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZ94-1", "uniprot_id": "D3ZZ94_RAT", "id": "D3ZZ94-1", "name": "Poly [ADP-ribose] polymerase", "aln": "---MAEEESGAALELWGLLPEIPDELLTLYFENHRRSGGGPLLSWQRLGCGGILVFQDPADAKRALAQTEHRLHGVQLTLRPAPPRAPERVLLQHLPPGTSPLSLEQHVQALLCAAGHPVQTCCVLASPRQDCALVQLSMPLSEADVCALVEQARNLPLNGATVSLAWVPQTRAVRVVDSPASVDLLLLELYLENERRSGGGPLEGMRSLPGKLGTVISFRQWQVAERVLKQKHWLQGSELCLVPHYDVLEPEGLAEGISGGDHSATQESGVTDGALTEAGGLAASLT----VAVGSGEAPGQLGTFLRAGPVETPGQAMPVDPG--------SVR-QGIMGSASSGDPVESFTE---------------RPEQAGPMTTDSVG----------VQECEGLEEVAIGSPGQEGTRGLVGTAMESVETG-LESPGYGEMQKHE-------------------------------------------------------------------------------DLVEMVLSMEPGAMRFLQLYYEDLLVSLEDVALFPLEGVDVTGFRLCGARAPCQAAQELLQSLLGSVSCHMLNMKHPGSARFLLGVEGQHLLHRLEAQFQCVFGTEHLASATLVID--------------PERTDPTEALQVLHA--------HSTGINQESMRLEEVQELLATLEG----------LEDRVPLEMEEEKAGEPEETVLEREEEIPTLEAEEEP-----GAPGQLEEEATLQLAIHRSLESQSQVADQQEANALRQAMALSLL-----EAEEPLDE------DTRGRAQLVVHTSFEQDMDELNQALSDALEGHLQEETVS----LQGCMLPSELAARLERCYDVSVTLHGDHAGLRGFGVQPARAARHLSALLVGPQ---------------------------------------------------DQNLTFPLEASKNNLSEQGLKEPLG-------------------------RLETLEENSKEFQDVVRAFYDTLDAAHSKICIVRVERVSHPLLQQQYQLHRERLMQRCQQQPVEQVLYHGTSESAVLDICAHGFNRSFCGRNGTLYGQGVYFAKRASLSVLDRYSPPNAEGHKAVFVAQVLTGDYGQGSRGLKAPPLRASGQVLR-YDSAVDCLHQPKIFVIFHDTQALPTHLITCKNIHLGTP-------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CIE4-1", "uniprot_id": "PAR10_MOUSE", "id": "Q8CIE4-1", "name": "Protein mono-ADP-ribosyltransferase PARP10", "aln": "---MAEVEAGAALELRGLPPEIPDELITLYFENHRRSGGGLLLSWQRLGCGGVLIFQDPADAKRVLAQAEHRLHGVRLSLRPAPPRAPERVLLQHLPPGTSPLSLEQHVQALLGAAGHPVQTCHALASPRQDCALVQLSTPLSEAEVSALAEQARNLPLNGATVSLAWVPQTRAVRVVDSASPVDLLLLELYLENERRSGGGPLEGLRSLPGQLGTVISFQQWQVAERVLKQKHWLQGIELSLVPHYDVLEPEALAEGVSGRDHSATQESGVIGHAPTGTGGLAGALT----MAVGSGEAPQQLGTLLRAGPVGAPGQALPVDSG--------SIRIQGSMGSTSPVDPVESSTE---------------LPEQVGPMASDSVG----------VQEQEGLGEVATG---QEGLMGLVGTAMESVETG-LESPGYGEMQKQE-------------------------------------------------------------------------------GLVEMVMSVEPGAVRYLQLYYEDLLASLEDVALFPLEGTDVTGFRLCGARAPCQAAQELLQSLLGSISCHTLNMKHPGSARFLLGVEGQHLLHRLEAQFQCVFGTEHLASATLDID--------------PERTDPTEALQVLHG--------HITGIDQESLRLEDVRELLATLESPH------G-GEDRVPLEMEKEKPGGPGETVVEQQEEIPTLEAEEEPVALSTGARGQLEEEATLQLAIHRSLESQSQVADQQEANALRRAMALSLL-----EAEEALDE------DTGGEAQLVVHTSFEQDVDELNQALSNALEAHLREETVS----LQGRMLPPELGARLERCHDVSATLRGDRVVLRGFGVQPARAARHLAALLVDPW---------------------------------------------------DQNLTFPLEASKPNLSEQGLKEPLG-------------------------RLEALEENSQEFQDVVRAFYSTLDAVHGRIRIVRVERVSHPLLQQQYQLHRERLMQSCQQRPVEQVLYHGTSESAVLDICAHGFNRSFCGRNGTLYGQGVYFAKRASLSVLDRYSPPNAEGYKAVFVAQVLTGDYGQGSRGLKAPPLRVSGQVLR-YDSAVDCLQQPRIFVIFHDTQALPTHLITCKNILPGTP-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53GL7-1", "uniprot_id": "PAR10_HUMAN", "id": "Q53GL7-1", "name": "Protein mono-ADP-ribosyltransferase PARP10", "aln": "MVAMAEAEAGVAVEVRGLPPAVPDELLTLYFENRRRSGGGPVLSWQRLGCGGVLTFREPADAERVLAQADHELHGAQLSLRPAPPRAPARLLLQGLPPGTTPQRLEQHVQALLRASGLPVQPCCALASPRPDRALVQLPKPLSEADVRVLEEQAQNLGLEGTLVSLARVPQARAVRVVGDGASVDLLLLELYLENERRSGGGPLEDLQRLPGPLGTVASFQQWQVAERVLQQEHRLQGSELSLVPHYDILEPEELAENTSGGDHPSTQGPRATKHALLRTGGLVTALQGAGTVTMGSGEEPGQSGASLRTGPMVQGRGIMTTGSGQEPGQSGTSLR-TGPMGSLGQAEQVSSMPMGSLEHEGLVSLRPVGLQEQEGPMSLGPVGSAGPVETSKGLLGQEGLVEIAMDSPEQEGLVGPMEITMGSLEKAGPVSPGCVKLAGQE-------------------------------------------------------------------------------GLVEMVLLMEPGAMRFLQLYHEDLLAGLGDVALLPLEGPDMTGFRLCGAQASCQAAEEFLRSLLGSISCHVLCLEHPGSARFLLGPEGQHLLQGLEAQFQCVFGTERLATATLDTG--------------LEEVDPTEALPVLPGNAHTLWTPDSTGGDQEDVSLEEVRELLATLEGLD------LDGEDWLPRELEEE---GPQE---QPEEEVTPGHEEEEPVAPSTVAPRWLEEEAALQLALHRSLEPQGQVAEQEEAAALRQALTLSLLEQPPLEAEEPPDG------GTDGKAQLVVHSAFEQDVEELDRALRAALEVHVQEETVG----PWRRTLPAELRARLERCHGVSVALRGDCTILRGFGAHPARAARHLVALLAGPW---------------------------------------------------DQSLAFPLAASGPTLAGQTLKGPWN-------------------------NLERLAENTGEFQEVVRAFYDTLDAARSSIRVVRVERVSHPLLQQQYELYRERLLQRCERRPVEQVLYHGTTAPAVPDICAHGFNRSFCGRNATVYGKGVYFARRASLSVQDRYSPPNADGHKAVFVARVLTGDYGQGRRGLRAPPLRGPGHVLLRYDSAVDCICQPSIFVIFHDTQALPTHLITCEHVPRASPDDPSGLPGRSPDT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PNZ8-1", "uniprot_id": "A0A8M9PNZ8_DANRE", "id": "A0A8M9PNZ8-1", "name": "Poly [ADP-ribose] polymerase", "aln": "---MADSLEERSLEVLDIPDDLDDDFLVLYFENKRRSGGGRVVSLERRGNQALVVFED-AETAVSVSSKSHSLHNTTLTLRRKPPKDPGKLLLRGLNPDTPMDYVELFVENITRLD--LETEFTLYPSPNKDLVLIHLKK-RPSKDFQTLSDDVSKKSLHGAKVSLEQVVATDSILVSN-LSTQTEDVLELYFG-SIRSGGADVVAVSMLSDGR-AKVSFKDVKTVDRVLQKSHNLEDRDLVVEPYFDFLHAVVGQASAASQDGQSTLMDGMNLTEPVSSQSPTVSHP-MDSTSLGQANAQTNIIPVIPNLTPATAAEPLIQKECVSFVSVPDAAKHNLLRLSKLTEDLTKAHPQFDVSLAKDG-----VQIKGPDQIEVERLKNKVLEFLTGVVQDHQTYDKLKADFLGREDVKKRLDSSLKDFPSIYSVSDCTVTVTSSSRNTARQTHDLLKSRISEFTVPVANEYKSAIFSEEWSDFLTSLDFCSTTVSEDAGRINVVTLAGMEKDNKGKIVEFLSTPHQKETVLSMQPGMLKFLQLHHQDLLADMGEVILFPLESG--DGLSIQGDANVCQSAAELLSAIIGSVFTRSIVVKHPGISRFLLDDEGTSILAEMTAKFEVYIDMTKVHWEPLEDKDILELAWKMTPCQNFQKSSSANSIQEFTAG-----VPNGATDAHASARIEEAKKILAVIGSDFNPAPSSSGSTNTDTQDIYSDPSEEIIEVNSDSDDQPQPLQTLDLPSFSAPTNVCNLDEDASLLLAIQLSMEINQRKDNDDIQKALELSKRDSVPREENKQLEMAFEMSMEEAIRLSNTAEIFVYANYNHDLVRVDIALGKKVGLRQCEEKIENKILRKLSSFQKRCIDLIKRKHAVEINIQGTTAILSGFKEYVSVAVPDLKDVLRRTEHMMSDAGIAKSVQWVWYEQGSSKGTPYSPEATVFIENAWKLKQKKIDILFNNQPYSIDLEKMEEHSLASGKSVPIKRKMMSTEDLYTDGADEDYSLLSSMPEVSTVDVNSDEFQDVVKEFYDTLQDNHNKIRIIKVEKLMNKLLHDQYRLKKASIEQSTSEPQFERTLYHGTSETSVKEICIHGFNRSFCGKNATVYGQGVYFAVNASLSVSDTYSPPNADGHKFIFVAKVLTGEFTVGKHEMKAAPLKENSAVPFRYHSVTDQINSPTLFVIFNDTQAYPKYLITCKKIYG----------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **: ::*: .: : *:::.*****:****** ::* :* * .:: *.: *:: ::. .* **.. *:** **: * ::**: * *.*. :* .*: : .**. * .*::* .. :. .* ::. : *.*: *** * : :: * . :. :****: . ****. : : *.. : **:: :..:***::.* *:. :* : *::*.*.. . :. * :* : . . : ::*..: : . : . : : : * : ..: . : . : : : : :: . :*. : :: .. . * : . * *: ::** :::***:::***..: :* *:***. *: : * **:* *:* :::**: : : ::*** :****. ** :* : *:*: :. :: .* :. ..:::: : . . : : . :*:.:::**.: . : . :: .: * : ::: . . : * *:*:*:* **:: *:* : : ::: **. : *: : * . : . *::.*:: :::*: .:: ** : : **.: : . ::* : *. ::* . * ** : *. .* :* . :* :: * . . * .:. : *: ***:**: **.**: :. * :::**:: : **::**.* : : * .. .*:.*****: .:* :** *********:*.*:**:***** .***** * ******:*:* :***:****:: * : ::*.**: . * *.*..* : .* :****:**** *.:****::: ", "identical_positions": 237, "similar_positions": 319, "identity": "19.47%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-183", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NBA8-1", "uniprot_id": "DTWD2_HUMAN", "id": "Q8NBA8-1", "name": "tRNA-uridine aminocarboxypropyltransferase 2", "aln": "MESQKEARTLQEPVARPSGASSSQTPNDKERREGGAVPAAAALGAEADDDSADGLWELPVEPAERRPECTRCSRPQKVCLCPFLPAHPLHISTHLYIIQHPAEENKVLRTVPLLAACLPQDKCKVKIGRRFSEER-DPELSTVCRKSGTLILYPGAEAANLEEFILDS---PVYPSTIIIIDGTWSQAKDIFYKNSLFRHPKQVQLKTSISSQYVIRMQPTNRCLSTLECAAVALSILEKNNYIQETLLR--------------PLQALCSFQLQHGAQIR---LSKEHLLKNGLYPKPMPKNK--RKLRKMELLMNSVKI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D0U1-1", "uniprot_id": "DTWD2_MOUSE", "id": "Q9D0U1-1", "name": "tRNA-uridine aminocarboxypropyltransferase 2", "aln": "MEPQAEERTLGEPAPPPSGALASPTPDEEERTEGGAPPTATPAGASGDSTSADGLWGLPVEHAERRPECGRCSRPQKVCLCPYLPVRPLQISTHLYIIQHPAEESRVLRTVPLLAACLPPDRCTVKIGRRFSEER-DVELATVCRDSGTLILYPGAEATNLEEFILDS---PVYPSTIILIDGTWSQAKDIFYKNSLFRLPKQVQLKTSVCSQYVIRMQPTNRCLSTLECAAVALSILEKNNCIQETLLR--------------PLQALCSFQLQHGAQIR---LSKEYLLRNGLYPKPMPKNK--RKLRKMELLMNSVKI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZGK2-1", "uniprot_id": "D3ZGK2_RAT", "id": "D3ZGK2-1", "name": "tRNA-uridine aminocarboxypropyltransferase", "aln": "MEPQEEARTLGESAPRPSGAWGLPTPGEEERSEGGARLAAPPAGALGDSTSADGLWGLPVEHAERRPECSRCSRPQKVCLCPYLPVRPLQISTHLYIIQHPAEESKVLRTVPLLAACLPPDKCTVKIGRRFSEER-DIELSTVCRDSGTLILYPGAEATNLEEFILDA---PVYPSTIILIDGTWSQAKDIFYKNSLFRLPKQVQLKTSICSQYVIRMQPTNRCLSTLECAAAALSVLEKNSCIQECLFFSTDSASPSSGSVFFPASAWCSGSPQQGVSSQEWIISQAYAKEQTQTQEDGAVNQQCQNLAHLSLRAGFPVIG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9PQP1-1", "uniprot_id": "A0A8M9PQP1_DANRE", "id": "A0A8M9PQP1-1", "name": "tRNA-uridine aminocarboxypropyltransferase", "aln": "MSS-----EFDEETAVISGQ------EEESRGEEEEEEEEKKEEEEEDDEGFSVLSELPVEKSERRPTCRRCCRPLKVCLCPFLPSRPLDVSTCLYIVQHPAEESRVLRTVPLLAACLPVAKCRVLVGRRFSEDR-YPELAAVCRDSHTLVLYPGADAHNLEELQPHTGDTHTNTHTLILIDGTWSQARDMFLKNTLLQLPRQVQLCSAPSSQYVIRTQPNNMCVSTLECAAVALSVLENDHNIQEVLLR--------------PLRALCSFQLQHGAQVH---HSKEQLIRSGEYKKSLPRNK--RKIRRMQKLISNHTI-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VI85-1", "uniprot_id": "DTWD2_DROME", "id": "Q9VI85-1", "name": "tRNA-uridine aminocarboxypropyltransferase 2", "aln": "---------------------------------------------MEDDAWLD-LVGISADPPNRRNKCEKCKRPVVVCWCPALPHPPEAVSSQIVILQHPAEEKRSLRTALMLQLGLEPGKCVVYKGKRFPNHRNHADLQRILDSPQTLLLYPSRDSVPLEEVDHSAG-----PYTLVLIDGTWPQAKAIYASSPALHRLRQVKLIAVGISDYIIRTQPTEGCLSTLETAAQCLAVLESRPELRQTLVR--------------PLHTLCKYQLDNGAVEH---QSKEFLLKNNQYPKPIGKRLS-RLLRNTACDGNEET--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. . * :..: .:** * :* ** ** ** ** * :*: : *:******.: ***. :* * :* * *:**.:.* :* : .. **:***. :: ***. : . *:::*****.**: :: ... :: :**:* : *:*:** **.: *:**** ** .*::**. ::: *. * : *. . ::*. : *: .. : . : : . . ", "identical_positions": 75, "similar_positions": 77, "identity": "23.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-186", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9Z2D3-1", "uniprot_id": "GSDME_MOUSE", "id": "Q9Z2D3-1", "name": "Gasdermin-E", "aln": "MFAKATRNFLKEVDAGGDLISVSHLNDSDKLQLLSLVTKKKRYWCWQRPKYQILSATLEDVLTEG-HCLSPVVVESDFVKYESKCENHKSGAIGTVVGKVKLNVGGKGVVESHSSFGTLRKQEVDVQQLIQDAVKRTVNMDNLVLQQVLESRNEVLCVLTQKIMTTQKCVISEHVQSEETCGGMVGIQTKTIQVSATEDGTVTTDTNVVLEIPAATTIAYGIMELFVKQDGQFEFCLLQGKHGGFEHERKLDSVYLDPLAYREFAFLDMLDGGQGISSQDGPLRVVKQATLHLERSFHPFAVLPAQQQR-----ALFCVLQKILFDEELLRALEQVCDDVAGGLWSSQAVLAMEELTDSQQQDLTAFLQLVGYR----------IQGEHPGPQDEVSNQK------------LFATAYFLVSALAEMPDNATVFLGTCCKLHVISSLCCLLHALSDDSVCDFHNPTLAPLRDTERFGIVQRLFASADIALERMQFSAKATILKDSCIFPLILHITLSGLSTLSKEHEEELCQSGHATGQD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60443-1", "uniprot_id": "GSDME_HUMAN", "id": "O60443-1", "name": "Gasdermin-E", "aln": "MFAKATRNFLREVDADGDLIAVSNLNDSDKLQLLSLVTKKKRFWCWQRPKYQFLSLTLGDVLIED-QFPSPVVVESDFVKYEGKFANHVSGTLETALGKVKLNLGGSSRVESQSSFGTLRKQEVDLQQLIRDSAERTINLRNPVLQQVLEGRNEVLCVLTQKITTMQKCVISEHMQVEEKCGGIVGIQTKTVQVSATEDGNVTKDSNVVLEIPAATTIAYGVIELYVKLDGQFEFCLLRGKQGGFENKKRIDSVYLDPLVFREFAFIDMPDAAHGISSQDGPLSVLKQATLLLERNFHPFAELPEPQQT-----ALSDIFQAVLFDDELLMVLEPVCDDLVSGLSPTVAVLG--ELKPRQQQDLVAFLQLVGCS----------LQGGCPGPEDAGSKQ-------------LFMTAYFLVSALAEMPDSAAALLGTCCKLQIIPTLCHLLRALSDDGVSDLEDPTLTPLKDTERFGIVQRLFASADISLERLKSSVKAVILKDSKVFPLLLCITLNGLCALGREHS-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9U2-1", "uniprot_id": "E7F9U2_DANRE", "id": "E7F9U2-1", "name": "", "aln": "MFEIATKKFVRHIDPSGVLIPASSLNDSKNLQLLAVVLKSKKRWFWQRIKYRPTEFTLNNLLKEKKTQLKPEYKKEEFVKYMETNRNVLGGSVDVSGPDVTLNLNGRSISNLYLRLGRLQKEYLDIPKLLNDTRGRKLDLKHSLIKQSK-NKNKTFAILKERIFTTCNGKINWNEEEKSGCQTVFTVFWNKMSIEGS--GKQHHGSETKLDIPPDTVLAYSVMEISIDAEGCFELCLFPRGLGTDETSEIPSPVPSEVDGQFPLMQEGFPLHTQKKALADVQTCFCALADLSVELRFSILVLLRKIMLDRTILSALVDTLETLSSDEAPCFLTKELSEKQSQIIREFLHLLKWESHENNQYPTSTSLSITNGCQKSTANHSHPVMASDQNGGHSAKSNQNGCSKAASKPSMELMYAMQMLLCALEELTDAGLKLLEPFCTSEHLSSLQDLVIHLTS-IMPLCKNTVPVSLQNEDEFHRKEELFKSCNVLLKKENDSLTSEVTCSVGFLPLVLCIAIHGLASLSAV---------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** **::*::.:*..* **..* ****.:****::* *.*: * *** **: . ** ::* * .* :.:**** . * .*:: . .*.**:.* . : :* *:*: :*: :*:.*: *.::: : :::* .:*:.:.:*.::* * : *. : : :. * :. : :.:.:..: *. .::. *:**. *.:**.::*: :. :* **:**: * * .. ..* : : .: : : * . * * :* * :. * ** :: : *: : :.:. : :* . * .:: * : . * .. *:* *: : :*:.** *:.* . :* . *. . :.:* *: *:. : .:.. ..*:: :.* :.** *.:: *:: : * .: : . .:**:* *:: **.:*. ", "identical_positions": 112, "similar_positions": 180, "identity": "20.74%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-187", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C0M0-1", "uniprot_id": "WDR59_MOUSE", "id": "Q8C0M0-1", "name": "GATOR2 complex protein WDR59", "aln": "MAARWSSENVVVEFRDSQATAMSVDCLGQHAVLSGRRFLYIVNLDAPFEGHRKISRQSKWDIGAVQWNPHDSFAHYFAASSNQRVDLYKWKDGSGEVGTTLQGHTRVISDLDWAVFEPDLLVTSSVDTYIYIWDIKDTRKPTVALSAVAGASQVKWNKKNANYLATSHDGDVRIWDKRKPSTAVEYLAAHLSKIHGLDWHPDSEHIFATSSQDNSVKFWDYRQPRKYLNILPCQVPVWKARYTPFSNGLVTVMVPQLRRENSLLLWNASDLNAPVHTFVGHDDVVLEFQWRRQKEGSKDYQLVTWSRDQTLRMWRVDYQMQRLC-ANDILDGVDEFIESISLLPEPEKTPHPQDIDHQPSLSHGEEDAIKE-DPPSSLLEEKRSDQLGLPQTLQQEFSLINVQIRNVNVEMDAADRSCTVSVHCSNHRVKMLVTFPAQYPNNAAPSFQFINPTTITSAVKAKLLKILKDTSLQKVKRNQSCLEPCLRQLVSCLESFVNQEDSASSNPFALQNSVTPPLPTFARVTTAYGSYQDANIPFPRTSGARFCGAGYLVYFTRPMTMHRAVSPTEPTPRSLSALSAYHTGLIAPMKIRTEAPGNLRLYSGSPTRSEKEQVSISSFYYKERK------------------SRRWKSKREGSDSGNRPIKAAGKVIIQDVSCLLPVHKSLGELYILNVNDTQETCQKNATSAMLVGRKDLVQVWSLATVATDLCLGPKSDPDLETPWARHPFGRQLLESLWGDRESTRVCGPPLSGARLAHYCQLRDVQTLAMLCSVFEAQSRPQGLPNPFGPFPNRSSNLVVSHSRYPSFTSS----GSCSSMSDPGFNTGGWNIAGRETEHISSPWGESSPEELRFGSLTYSDPRERERDQHDKNKRLLDPANTQQFDDFKKCYGEILYRWGLREKRAEVLKFVSCPPDPHKGIEFGVYCSHCRSEVRGTQCAICKGFTFQCAICHVAVRGSSNFCLTCGHGGHTSHMMEWFRTQEVCPTGCGCHCLLESTF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PJI9-1", "uniprot_id": "WDR59_HUMAN", "id": "Q6PJI9-1", "name": "GATOR2 complex protein WDR59", "aln": "MAARWSSENVVVEFRDSQATAMSVDCLGQHAVLSGRRFLYIVNLDAPFEGHRKISRQSKWDIGAVQWNPHDSFAHYFAASSNQRVDLYKWKDGSGEVGTTLQGHTRVISDLDWAVFEPDLLVTSSVDTYIYIWDIKDTRKPTVALSAVAGASQVKWNKKNANCLATSHDGDVRIWDKRKPSTAVEYLAAHLSKIHGLDWHPDSEHILATSSQDNSVKFWDYRQPRKYLNILPCQVPVWKARYTPFSNGLVTVMVPQLRRENSLLLWNVFDLNTPVHTFVGHDDVVLEFQWRKQKEGSKDYQLVTWSRDQTLRMWRVDSQMQRLC-ANDILDGVDEFIESISLLPEPEKTLHTEDTDHQHTASHGEEEALKE-DPPRNLLEERKSDQLGLPQTLQQEFSLINVQIRNVNVEMDAADRSCTVSVHCSNHRVKMLVKFPAQYPNNAAPSFQFINPTTITSTMKAKLLKILKDTALQKVKRGQSCLEPCLRQLVSCLESFVNQEDSASSNPFALPNSVTPPLPTFARVTTAYGSYQDANIPFPRTSGARFCGAGYLVYFTRPMTMHRAVSPTEPTPRSLSALSAYHTGLIAPMKIRTEAPGNLRLYSGSPTRSEKEQVSISSFYYKERK------------------SRRWKSKREGSDSGNRQIKAAGKVIIQDIACLLPVHKSLGELYILNVNDIQETCQKNAASALLVGRKDLVQVWSLATVATDLCLGPKSDPDLETPWARHPFGRQLLESL------------------LAHYCRLRDVQTLAMLCSVFEAQSRPQGLPNPFGPFPNRSSNLVVSHSRYPSFTSS----GSCSSMSDPGLNTGGWNIAGREAEHLSSPWGESSPEELRFGSLTYSDPRERERDQHDKNKRLLDPANTQQFDDFKKCYGEILYRWGLREKRAEVLKFVSCPPDPHKGIEFGVYCSHCRSEVRGTQCAICKGFTFQCAICHVAVRGSSNFCLTCGHGGHTSHMMEWFRTQEVCPTGCGCHCLLESTF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A286YB35-1", "uniprot_id": "A0A286YB35_DANRE", "id": "A0A286YB35-1", "name": "", "aln": "MAARWSSENVVVEFRDAQANAMSVDCLGQHAVLSGRRFLYVVNLETPSEAPRKISRQSKWDVGTVQWNPHKSDAHIFAASSNQRVDLYTWRDGSGKSHTSLQGHTRVISDLDWSWFEPEFLVTSSVDTYIYIWDTSDTRRPTVTLSAVAGASQVKWNRRNHYCLASSHDGDVRIWDKRKSNTAVEYVAAHLSKINGLDWHPDNEYILATSSQDNSVRFWDYRQPRKYLDILSCQVPVWKARYTPFSNGLVTVMVPQLRRENSLLLWSTLELNSPVHAFVGHDDVVYEFQWRPQKEGSKDCQLVTLSRDQTLRIWRVDPQLQKLCCANEIVD---------ELTTETEKTLRSQDSEPPLSPGFTADNSLDQFDGPQSGLSS--SAKNDIPQTLQQEFSLVNLQIRNVNVEMDAVNRSCFVSADCGANRVRLVVKFPAQYPNNAAPSFQFVPPTNISSSMKIKIQKILTDTSLQKVKRNQNCLEPCVRQLVSCLESDGVMED--GSNPYVLTNPVTPALPAFPRVTNTYGSYQDANIPFPRTSGARFCGTGSLVYFTRPMTMHRATPPTEPTPRSLSALSAYHSGVMTPMKMRTESQTTLRLYSGSPTRTDKDQVSISSFYYKERKPLSAARRWSVQTIHECPKSRRWKGKREGGDYSNRPIKLAGKVIIQEISCLLSVHKALGETYVLNVNDIQDTCQKNGAAALAVARRDLAKVWALASASTNLNLSPDPDPDAGTPWAKHPFGRHLLETL------------------LEHYSQLSDVQSLAMLCSVFRGHGSPQEYFTLYGHQQPRPAVFTPHHSRYPSFTSSSVTSGSCSSTSDSANTP--WNTGGRESEHPPS-WGESTPDDYRYANQTYTDPREREKEQHDMNKRLLDPSNSWQFDDFKKCYGEILHRWGMKDKRAEVLKFVSCPPEPHKGIEFGVYCCHCRSQARGTQCAVCKRFTFQCSICHVAVRGSSNFCLSCGHGGHTSHMMDWFRSQDVCPTGCGCHCLQQSTF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****************:**.********************:***::* *. **********:*:******.* ** ************.*:****: *:*************: ***::************** .***:***:*************::* **:*************..*****:*******:*******.*:*:*********:***********:**.**********************************.. :**:***:******** ***** ******* **** *******:**** *:*:** **:*:* .* .*.*** :.:* : : .. ::::.: * * . *.. * : .:**********:*:***********.:*** **..*. :**:::*.***************: **.*:*::* *: ***.**:******.*.*****:********* ** .***:.* *.***.**:*.***.:*********************:* *************..****************:*:::***:***: .**********::*:************* *****.****.* .** ** *******:::***.***:*** *:***** *:*****.::*: *.*:**.:**:**:.:*:* *.*..*** ****:*****:***:* * **.:* ***:********..:. ** . :* *.: :. ********** ***** **.. .. ** .***:** .* ****:*:: *:.. **:******::*** *******:*: *************:***:::*************:***********.****:.******:** *****:**************:***********:***:*:*********** :***", "identical_positions": 697, "similar_positions": 184, "identity": "68.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-191", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K3T4-1", "uniprot_id": "FFAR1_RAT", "id": "Q8K3T4-1", "name": "Free fatty acid receptor 1", "aln": "--MDLPPQLSFALYVSAFALGFPLNLLAIRGAVSHAKLR-LTPSLVYTLHLACSDLLLAITLPLKAVEALASGVWPLPLPFCPVFALAHFAPLYAGGGFLAALSAGRYLGAAFPFGYQAIRRPCYSWGVCVAIWALVLCHLGLALGLEAPRGWVDNTTSSLGINIPVNGSPVCLEAWDPDSARPARLSFSILLFFLPLVITAFCYVGCLRALVHSGLSHKRKLRAAWVAGGALLTLLLCLGPYNASNVASFINPDLEGSWRKLGLITGAWSVVLNPLVTGYLGTGPGQGTICVTRTPRGTIQK--------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q76JU9-1", "uniprot_id": "FFAR1_MOUSE", "id": "Q76JU9-1", "name": "Free fatty acid receptor 1", "aln": "--MDLPPQLSFALYVSAFALGFPLNLLAIRGAVSHAKLR-LTPSLVYTLHLGCSDLLLAITLPLKAVEALASGAWPLPLPFCPVFALAHFAPLYAGGGFLAALSAGRYLGAAFPFGYQAIRRPRYSWGVCVAIWALVLCHLGLALGLETSGSWLDNSTSSLGINIPVNGSPVCLEAWDPDSARPARLSFSILLFFLPLVITAFCYVGCLRALVRSGLSHKRKLRAAWVAGGALLTLLLCLGPYNASNVASFINPDLGGSWRKLGLITGAWSVVLNPLVTGYLGTGPGRGTICVTRTQRGTIQK--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14842-1", "uniprot_id": "FFAR1_HUMAN", "id": "O14842-1", "name": "Free fatty acid receptor 1", "aln": "--MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLR-LTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK--------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RMS0-1", "uniprot_id": "A0A8M1RMS0_DANRE", "id": "A0A8M1RMS0-1", "name": "", "aln": "MELSASSYVSMLVYIFTFLLGLPGNLLVLFVYIRKARKHGATPNVVYALNLCVANLALVLWMPVKVAETVLQG-WELPALVCPVYSFFLFSSVYGSSLILTAVVVGRYLSIAFPITYKIYRRARTSCLVSAVLWALVFLHLGFAVLAEGGGHFVSLSEQ------NVSACYENFTKEQLDVLVPLRLEMALLLFLLPLVLSAFCTLRCLVLVRHSSLPSCGKKRVLAIALSTLIVFVVCYGPYNVSHIVGFVLYTN-VEWRSEAMLTSSCNIFLEPVVMLMLSPWTPRDLLDRLCHRRRDASRKWWDQNYRVSRNPQTTTTQVASIISHRESEKARANTTD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .. :*: :*: :* **:* *:*.: :*: : **.:**:*:* ::* *.: :*:*..*:: .* * ** .***::. * .:*... :*:*: .****. ***: *: **. * *...:****: ***:.. * ::. : *... : : * *:.:::***:***.::*** : ** : :*.*. * *. :* .:*:.:::* ****.*::..*: .**. .::*.: .:.*:*:* *. . : .: ", "identical_positions": 85, "similar_positions": 111, "identity": "24.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-196", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZSC1-1", "uniprot_id": "D3ZSC1_RAT", "id": "D3ZSC1-1", "name": "", "aln": "---MSAGPQWPA--PRSLP-ALCAALLLLALQPPPVRAEGKLFVLDSQ---NGSQGLDLETARQSCKSRGAHLVSAGELKRVVQDCASAVCTTGWLADGTLGTTVCSKGSGEQPVLRAIDVTIDSHPVPGAKYNALCIKDEERPCGDPPSFPHTILQGRTGLEMGDELLYVCVPGSVTGHRETAFTLLCNSCGEWYGLVQACGKDEAEAHIDYEENFPDDRSVSFR-ELMEDSRAEGEKEKAQEDASDETPKQDRLVFTSVSKENIAQEKAFVPTTGLPGAGSSFHTDWPRSRLHRKYSLWFPAETFHKSELEKDVDDETKEPLPARDTHSDEKPAPEESETRLVYATTYSPSEPFADRNDSKAEDIGVSSSDDSWLDGYPVT-------DGAWRKVEAGQEDDEDKGD-----------------------GSVGPDDSVLMSPDQ--------PIKNVTVISSESVIYSSISPS---QMLDVEALVPGPINVSETERPHTGDADLTNYQSTIPRRVTTQQSPMATSPSELTTSTTQETVLTTLQPTHKHSPSSNVEATQPPAEVTAPEVQDNFPYLLSEDFLGQ----EGPGPGASEERLLPTLAPCVGDECPSFRKGPVIATIVTVLCLLFLLAVSGAVWGYRRCQHKSSVYKLNVGQRQARHYHQQIEMEKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "G3UW60-1", "uniprot_id": "G3UW60_MOUSE", "id": "G3UW60-1", "name": "", "aln": "---MSAGPLWPA--PGSLP-ALCAALLLLALQPPPVRAEGKLFMLGSQ---NGSQGLDLEAARLSCRSRGAHLVSAAELKRVVRDCASAVCTTGWLADGTLGTTVCSKGSGEQPVSRAVDVRIDSHPVPGAKYNALCIKDEERPCGDPPSFPHTILQGRTGLEMGDELLYLCAPGSVPGHRETAFTLLCNSCGEWYGLVQACGKDEAEAHIDYEENFPDDRSVSFR-ELMEDSRAEGEKEKAQEDASDETPKQDRLVFTSVSKENIAQVKAFVPTTGSPGAGGSVRTDWPRSRLHRKYSLWFPAETFHKPELGKDEGDETKEPLPARDNHSEEKPAPEESETRLVYATTYSPSEPFVDRNDSKAEDPGVSSSDDSWLDGYPVT-------DGAWRKVEAGQEDDEDKGD-----------------------GSVGPDESGLTTPDK--------EPENVTVTPSESVIHSSISPS---QMLDVEALVPGPINVSETESSHTRDVDSTSSQSTIPRRVTTQPSPKVTSPHELASS-TQETVTTTLQPTHKRTPSTDVEATQPPAGVTAPEVQDNFPYLLSEDFLGQ----EGPGPGAS-EKFLPTSAPCVGDECPSFRKGPVIATVVTVLCLLLLLVVAGAVWGYRRCQHKSSVYKLNVGQRQARHYQQQIEMEKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O60279-1", "uniprot_id": "SUSD5_HUMAN", "id": "O60279-1", "name": "Sushi domain-containing protein 5", "aln": "--MTAEGPSPPARWHRRLPGLWAAALLLLGLPRLSVRADGKFFVLESQ---NGSQGLQLEAARLSCKSRGAHLASADELRRVVQDCSFAVCTTGWLADGTLGTTVCSKGSGEQQIMRAVDVRIESNPVPGGTYSALCIKDEEKPCGDPPSFPHTILQGRTGLEMGDELLYVCAPGHIMGHRETAFTLLCNSCGEWYGLVQACGKDEAEAHIDYEDNFPDDRSVSFR-ELMEDSRTEADEDRGQGDSSEEAPKQDRLVSISVGRENIARDKVFVPTTGLPGAGSSVPADSPGSRLLQKHLFWFPAEAFHKPGLEKEVDDDTKKQFSAGDNHSGVKLVPGEPETKVIYGNTDGPSGPFVGKNDSKAGDPVVSSSDESWLDGYPVT-------EGAWRKTEAEEEEDGDRGD-----------------------GSVGLDENVLVTPDQPILVEVK-KPKSSTLTPSEGMTHSSVLPS---QMLDVEALALRPVNASETEG--IGDGDLTKYQSTLPWRFITEESPMATLSYELTSSTLEILTVNTVKQTPNHIPSTIMATTQPPVETTVPEIQDSFPYLLSEDFFGQ----EGPGPGAS-EELHPTLESCVGDGCPGLSRGPVIATIVTVLCLLLLLAGVGMVWGYRKCQHKSSVYKLNVGQRQARHYHQQIEMEKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ASV6-1", "uniprot_id": "A0A8M3ASV6_DANRE", "id": "A0A8M3ASV6-1", "name": "", "aln": "MWRAGHQERA-------------LLLLMVWLTRADASPLGRVFLLELESFSKGGQEDGFEAAAQACMAQGARVASGADLHHAVLECAFSACSRAWLSGPSVGSTVCSGVPG---HLRPVDVQLENSTANTESLGVFCVKDSDAPCGQPPSFPHSHLQGKTGLDLGDELLYACDPGHKLPNGETAFSLLCDSCGEWYGLVQHCVKDDPEGHIDYEDKFTDDHLLENSEEHHHISLTSGGTQSTQREEEKKSTPEPVLERTALSDEKNDEDSTISATEP------------PVSQLSQKHMFWFPSEAFQE---EKGHVGITTDSFKNPTEDESVKTADSQSDPDVITD------EHLTDPPTEEPSSPNVEATDDSWLDGYPVGQEEDKAGGGSTGEAGPEHEAETETGQSEVEVFEDAASKKPVEEETGGLIGSPDEEDSIHIKGDEEQLTRLEEESVGIHEDTTEGITKDGEVHTPEKTALEFDGVTESPNGLGVKTTTIIMKITPSPGDIALNKRPMVYTPASAPENVSTSQEGLDNTSTTSGMVHLDEITSIPTAVIKDPWEAIDDHLMEHIPGYVPTDTPENQSMMEQGGDHSLDQQERDLVGGCVEDPCHGAGHGPMIAAIIVGVVAALAGVVLG-VWCYKKRQQKSSHYQLNGTNRQTQSIELQQTV---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . **:: * . . *:.*:* : :*.* :*:* :* ::**::.*. :*::.* :*: :.*: .**:. ::*:**** .* *.:** ::. .. . ..:*:**.: ***:******: ***:***::****** * ** : ****:***:********** * **:.*.*****::*.**: :. * . * :.. : * : ..::. : * ::. *: . ..: .* * *:* :*: :***:*:*:: * . *.. : .. * . :.:. :: :.. .:. . *.::*:******** *: :. . .* : : *: ** . ::. . *: . .:*.: .. : *:.:.:. * . . . . : : :: * . .. .. . : . : .: .. .* . : * . .: : :* :. * : * * : :. ** * * . :**:**:::. : : . * ** *:: *:*** *:** :**:: . * : ", "identical_positions": 151, "similar_positions": 202, "identity": "22.34%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-198", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HB09-1", "uniprot_id": "B2L12_HUMAN", "id": "Q9HB09-1", "name": "Bcl-2-like protein 12", "aln": "-----------MAGSEELGLREDTLRVLAAFLR----------------------------------------------------------------------RGEAAGSPVPTP---------PRSPAQEEPTDFLSRLRR-----CLPCSLGRGAAPSES-----------------------------PRPCSLPIRPCYG------LEPGPATPDFYALVAQRLEQLVQEQLKSP-----PSPELQGPPSTEKEAILRRLVALLEEEAEVINQKLASDPALRSKLVRLSSDSFARLVELFCSRDDSSRPSRACPGPPPPSPEPLARLALAMELSRRVAGLGG--TLAGLSVEHVHSFTPWIQAHGGWEGILAVSPVDLNLPLD---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TD91-1", "uniprot_id": "A0A8N7TD91_DANRE", "id": "A0A8N7TD91-1", "name": "", "aln": "MADIVARPSSPPLSVSLLEIEAETRLVLKSFLRNTLAVAPGERPGRIGGEYHDPYKYSALKGRMKKDGNGWDSLDEEISAAEEKKHGIKNLIKRRLRPRSSTSRAKKSGSAEPTPNNTLEKQSLPAQPEKPSTNGAHSLPRKTEEEMRVPSSASEEEGDKKSGGKNKKKKKKSTISDLFKKVSFKKEEPRPQRPTKLPINYTDSPELDECVHSPSHPPAFYDDVAETLDRIAQKHSMKKRSPVKPMPLPSAPKENDKEAMVQQLVQILASEGDAINEKINDNPFLRSTLTRLSYPSFAKLLDMYASQSED-------PHVPPPVSPTLRRMAITMEASRRVVTATGAHRLTVYAERYMESFAPWLRSHGGWENIAQLDDSAINQSHLEYD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . * :. :* ** :*** *.: :**. *** * .* : .... * *: :*.* .. . .:* ** .***. . :.. . .* ** **: *:::.*:: . * * ..* ..:***::::** :* .*.:.**:*: .:* ***.*.*** ***:*::::.*:.:. * *** . .* *:*::** ****. * *: : .::.**:**:::*****.* :. :* . ", "identical_positions": 84, "similar_positions": 91, "identity": "21.54%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-203", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1Z8R4-1", "uniprot_id": "A1Z8R4_DROME", "id": "A1Z8R4-1", "name": "Hexosyltransferase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MFVLLLMYLSPRPVPDVHDRKAELSGWEREK-------------------------------------PLKIG-------------------------------------------------------------DYLDQGKNTALIVPRDFCKS--KALLVIAVCSGLDHFEQRSAIRQTWGNTKSFNYGEFVRLHGHLEGKYLSVMPGRLKLYSMYLSGLDDSLTAKIRIVFILGRSKNDSKR---ELDKLFRESIQHNDIIQENFVDSYHNLTLKSVMALKHISQSCADRAAFFLKCDDDTFVNVPNLLHFLLGGTIPLYKDTVGYHSRTTYKVKSPWNRLNGSRGLMYGHKFCNMKTVDDVKSPWYMPYYMFKGAKYPKYLSGTGYLMSIDVVKRLYAEALTTSLVHLEDVFVTGICAKKAGIRRRHQPLFN-YVHGKPLCIFKGTITMHPVPLHSMLDAWAFVSN-YSIKCLPPRKHFVKTELSKKSHC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A1Z8R6-1", "uniprot_id": "A1Z8R6_DROME", "id": "A1Z8R6-1", "name": "Hexosyltransferase", "aln": "--------------------------------------------------------------------------------MDRRWNPEKIEEQSSLLAAEYSSSSGAAASGSEDETVTTSG--------------------------ALRSKAKLRKRQLRNRMPLPRMLRRLGCYTLSAFLICGLLLVYL-PLVYLDVHKRSAGLPDWTSET-------------------------------------SRSIA-------------------------------------------------------------DYLDIGLSSGVIVPKDFCRN--KTFLVIAVCTGVDNFIQRHTIRETWGNTTEFNYPAFGKLHGHLKGHYLPPLPDRLKMYGDYLSGEGQSLTASVRIVFIVGRQKDEAMLGNETLNRIHIESEKYNDIIQENFVDSYNNLTLKSVMALKHISRSCFNTAVYFLKCDDDTFVNIPNLLNFLLGGTIPLYNDTLDYHDRSTYLVTAPQTRLKASSDVLYGHQFCNVVPVSEVSSKWYMPSYMYKPESYPKYLSGAGYLMSIDVVQRLFEASLNTTLVYLEDVYITGLCAQKAKINRHHHPLFS-FAHSKQMCAFKGTITQHQLKDDSMVSAWNYVSN-YSIKCPPPGRYFSQVRLRKRPIC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9Y5Z6-1", "uniprot_id": "B3GT1_HUMAN", "id": "Q9Y5Z6-1", "name": "Beta-1,3-galactosyltransferase 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASKVSCLYVLTVVCWASALWYLSITRPTSSYTGSKPFSHLTVAR-------------------------------KNFTFGNIRTR-------------------------------------------------------------PINPHSFEFLINEPNKCEKN--IPFLVILISTTHKEFDARQAIRETWGDENNFKG-------------------------------------IKIATLFLLGKNADPVLN-----QMVEQESQIFHDIIVEDFIDSYHNLTLKTLMGMRWVATFCS-KAKYVMKTDSDIFVNMDNLIYKLLKPSTKPRRR-------------------------YFTGYVINGGPIRDVRSKWYMPRDLYPDSNYPPFCSGTGYIFSADVAELIYKTSLHTRLLHLEDVYVG-LCLRKLGIHPFQNSGFNHWKMAYSLCRYRRVITVHQISPEEMHRIWNDMSSKKHLRC------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O54904-1", "uniprot_id": "B3GT1_MOUSE", "id": "O54904-1", "name": "Beta-1,3-galactosyltransferase 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASKVSCLYVLTVVCWASALWYLSITRPTSSYTGSKPFSHLTVAR-------------------------------KNFTFGNIRTR-------------------------------------------------------------PINPHSFEFLINEPNKCEKN--IPFLVILISTTHKEFDARQAIRETWGDENNFKG-------------------------------------IKIATLFLLGKNADPVLN-----QMVEQESQIFHDIIVEDFIDSYHNLTLKTLMGMRWVATFCS-KAKYVMKTDSDIFVNMDNLIYKLLKPSTKPRRR-------------------------YFTGYVINGGPIRDVRSKWYMPRDLYPDSNYPPFCSGTGYIFSADVAELIYKTSLHTRLLHLEDVYVG-LCLRKLGIHPFQNSGFNHWKMAYSLCRYRRVITVHQISPEEMHRIWNDMSSKKHLRC------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M6Z7E1-1", "uniprot_id": "A0A8M6Z7E1_DANRE", "id": "A0A8M6Z7E1-1", "name": "Hexosyltransferase", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSKVSCLYLLTVVCWASALWYLSGSRPSTAYVGQMTFIRKPILRF-----------------------------SKNDSFSNIRTR-------------------------------------------------------------TLNPHNFKFLINEPKKCEST--TPFLVLLISTNHKEFDARQAIRETWGDENTFSN-------------------------------------VHILTLFLLGYSTEPVLN-----QMVEQESQIFHDILVEDFVDSYHNLTLKTLMGMRWVSLFCP-NAQYVMKTDSDIFVNMDNLVFNLLRPNAKPRRR-------------------------FFTGHVINGGPIRDVHSKWFMPRELYPDSRYPPFCSGTGYVYSGDMAELLYKTSLHTRLLHLEDVYVG-LCLRKLGIQPFQNNGFNHWKMTYSLCRYRKVLTVHQISPEEILRIWNDMSNKKHLKC------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLS8-1", "uniprot_id": "Q9VLS8_DROME", "id": "Q9VLS8-1", "name": "", "aln": "MAAMANLHNTRMLRFFLVLIVVILTIFIYASYSTTSTLTANHVHPAASPPQQLIGSHPGRQPMDQVPPVNSTDKEYNSPPGESSSKQQSVSSRHSQQLPPQQAEIHKRHPQHRLPTIDEDALLDGGSAGASPQVGGPDQTPNVMADELLEEQQYGQSVDGITGNINSSTNNNSSADTLAVKQSIPAQSPQQQLPQSQSQVQPGLSDADLLIPTSNLQKFIENADRILKNITSNSSTGNPSDMAQLNAVDGKLEVSGVESEKQEPESKVIQEIKEAKKEAAVPLPKSAKPPVPPVKTTKSKVPSAPVDPSKGVATETLYEPGHVDEEIDAERICPKGGEFIKLLVLISSAMSHDAARMSIRQTWMHYGTRRD---------------------------------------VGMAFVLGRGTNETIN-----KALTQENFIYGDLIRGNFIDSYNNLTLKTISTLEWADVHCP-KAKYILKTDDDMFINVPKLLTFLDKHKDK---------------------------RTIYGRLAKKWKPIRNKKSKYYVSVDQFAAGVFPSFTTGPAYVLTGDIVHELYVRSLKTVYLKLEDVFTTGIVAKSLNVKRVQANEFVNRRISFNPCNIRNAISVHMIKSNEQFDLWKKLLD-QTTKCK-----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLT0-1", "uniprot_id": "Q9VLT0_DROME", "id": "Q9VLT0-1", "name": "Hexosyltransferase", "aln": "MAG-------RLLRCILILILVSFTVFTYVSK---------------------VG------VMEKVDYFT-------------TAKPDVMSKNPAIQLVG--EAIRLRSFREPIKDFDDG----------------------------FAVQISGNSSEGNK-DIYTTIDGN-----INVADSIAAIRSRR--IDEEKLHDDGLDSKDILAKKS----------------------------VVLYSIDTEVPVR-------------------------MPLVK------------------------------TIYKPGHLDSEIDMERICPQKGLSTQLLVLITSSLRHSAARMSIRQTWMHYGSRRD---------------------------------------VGMAFVLGKGKNKSVK-----KAIDQEDFMYQDLIRGHFIDSYNNLTLKTISLLEWADLHCP-KAKYVLKTDDDMFINVPKLLTLISTLKAN---------------------------RTIYGRRAENWKPIRNRWSKYHISNAQYGKPTFPYFTTGPAYLLTGDIVHALYVQSLNTAFLKLEDVFTTGIVAESLNIRRVNVREMANTRTKFETCHIRDKITIHMVRNNEQFTLWNMLLD-DTIKCDNQV--------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : . *:: : : . * :**:** . : *::* : . : *. . *:: .*:***:*****:: :. * * :.:* *.* *:*: :*: : . : : .: : * :.:. : :* : :*..*: : *:.. :: :* * : ****: : .. :. : : * : :: * : .. * : . :* ", "identical_positions": 42, "similar_positions": 79, "identity": "6.22%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-204", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q16719-1", "uniprot_id": "KYNU_HUMAN", "id": "Q16719-1", "name": "Kynureninase", "aln": "MEPSSLELPADTVQRIAAELKCHPTDERVALHLDEEDKLRHFRECFYIPKIQDLPPVDLSLVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLMKDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQLQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKPALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLTGYLEYLIKHNYGKDKAATKKPVVNIITPSHVEERGCQLTITFSVPNKDVFQELEKRGVVCDKRNPNGIRVAPVPLYNSFHDVYKFTNLLTSILDSAETKN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CXF0-1", "uniprot_id": "KYNU_MOUSE", "id": "Q9CXF0-1", "name": "Kynureninase", "aln": "MEPSPLELPVDAVRRIAAELNCDPTDERVALRLDEEDKLSHFRNCFYIPKMRDLPSIDLSLVSEDDDAIYFLGNSLGLQPKMVRTYLEEELDKWAKMGAYGHDVGKRPWIVGDESIVSLMKDIVGAHEKEIALMNALTINLHLLLLSFFKPTPKRHKILLEAKAFPSDHYAIESQIQLHGLDVEKSMRMVKPREGEETLRMEDILEVIEEEGDSIAVILFSGLHFYTGQLFNIPAITKAGHAKGCFVGFDLAHAVGNVELRLHDWGVDFACWCSYKYLNSGAGGLAGAFVHEKHAHTVKPALVGWFGHDLSTRFNMDNKLQLIPGANGFRISNPPILLVCSLHASLEVFQQATMTALRRKSILLTGYLEYMLKHYHSKDNTENKGPIVNIITPSRAEERGCQLTLTFSIPKKSVFKELEKRGVVCDKREPDGIRVAPVPLYNSFHDVYKFIRLLTSILDSSERS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IQY2-1", "uniprot_id": "A0A0R4IQY2_DANRE", "id": "A0A0R4IQY2-1", "name": "Kynureninase", "aln": "--------MMERILSVCEKLKCSPTSPTLAEHLDQRDHLRHLRELFIIPKTSQLSKVDLSLVDSSEDCIYFAGNSLGLQPKNTKKYIDEELEKWAKTGVHGHTEGSRPWAWAEETLEEMMAKIVGAKTEEVALMNGLTVNLHLLMLSFYKPTPKRHKILLEDKAFPSDHYAIESQIRLRGLNMSDSMLIIKPRQGEDVIRTEDIVSLIEREGESIALVMLSGVQYYSGQLFDMETITTAGHSKGCFVGFDCAHAVGNAELRLHDWNVDFACWCTYKYMNSGAGGLAGAYIHERHAHSIKPALTGWWGHDLKTRFLMNNEMDLQPGVNGFRLSNQPILLVCPLQASLEIFNQTTMKDLRSKSVLLTAYLEFLIRHYYSRDPSDPDRPSVHIITPSDPQQRGCQLSLSFSSPIRAVFEELEKRGVACDMREPNVLRVAPVPLYNSFTDVHRFITVLGSALSASRQ--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :. :*:* **. :* :**:.*:* *:*: * *** :*. :*****...::.*** ********* .:.*::***:**** ..:** *.*** .:*:: :* .****: :*:****.**:*****:***:******:***** *************::*:**::..** ::***:**:.:* ***:.:**.**:***::::**:::*:** *:: :**.**::***:**** ******.** ****.*******:***:*:****:***::**:***::****.**:**:*.*** *:*:::* **. ***:** ******.*:****:*:*:**. ** **:***.***::::* :.:* : . * *:***** ::*****:::** * : **:*******.** *:*: :*********** **::* :* * *.::. ", "identical_positions": 259, "similar_positions": 137, "identity": "55.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-214", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63624-1", "uniprot_id": "SFR19_RAT", "id": "Q63624-1", "name": "Splicing factor, arginine/serine-rich 19", "aln": "MEEEDESRGKTEESGEDRGDGPPDRDPALSPSAFILRAIQQAVGSSLQGDLPNDKDGSRCCGLQWRRCCRSPRSEPRSQESGGADMATVLDTAADSFLVELVSILDPPDTWVPSHLDLQPGESEDVLELVAEVRIGDRDPMPLPVPSLLPRLRAWRTGKTVSPQSHASRPACSRHLLTLGTGDGGPAP---PPAPSSASSSPSPSPSSSSP---------------------------------SPPPPPPPPPPPALPAPRFDIYDPFHPTDEAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEE--------GLSQSISRISETLAGIYDDNSLSQDFPGDDSPHREPPPPQTLGAPGTPPQADSTRAEGAPRRRVFVVGPEAEACLEGKVSVEVVTTAGGPALPLPPLPPTDPEIEEGEIVQPEEEPRVAVSLFRAARPRQPPASVATLASVAAPAAPPASAPRAPEGDDFLSLHADSDGE---------GALQVDLGEP---------------PAPPAADARWGGLDLRRKILTQRRERYRQRSASPGP-----------PPARKKARRERQRSG---------------DPAPPDSPT-WEAKKHRSRERKLGSHS--TARRRSRSRSRRRS---RSRSADRRRGS-HRSRSREKRRRRRRSASPPPAASSSSSSRRERHRGKRREGG--KKKKKRSRSRAEKRSGD-LEKLPAPVPP-SGS----DRDSRR--RGAVPPSIQDLTDHDLFAIKRTITVGRPDKTE--PRAPSPAPAVSPKREVLYDSEGLSADERGAKG-DKDRRRSGAASSS----------------------------------------------SSSREKASRRKALDG-------DRGRDRDRSSKKTRPPKDSAPGSGALPKAPPSSGS--SSSSSSCS-------------------------------------------SRKVKLQSKVAVLIREGVSSTTPAK-----------------DSSSSGLGSIGVKFSRDRESRSPFLK--------------PDERAPAEGVKVAPGST-----KPKKTKAKAKAGAKKAKGTKGKTKPSKTRKKVRSGGSSTASGGPGSLKKSKADSCSQAASAKGTEETSWSGEERTTKAPSTPPPKVAPPPP------------------------------------ALTPDSQTVDSSCKTPEVSFLPEEASEDTGVRVGAEEEEEEEE-------------------------EEEEEEE---QQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPAARASQLPTLPPPMPWNLPAGVDCTTSGVLALTALLFKMEEANLASRAKAQELIQATNQILSHRK---------PPSTLGVTPAPVPTSLGLPPG--PSSYLLPGSLPIGGCGSTP-----------------PTPTGLVPASDKREGSSSSEGRGDTDKYLKKLHTQERAVEEVKLAIKPYYQKKDITKEEYKDILRKAVHKICHSKSGEINPVKVSNLVRAYVQRYRYFRKHGRKPGDPPGPPRPPKEPGPPDKGGPGLPLPPL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5U4C3-1", "uniprot_id": "SFR19_MOUSE", "id": "Q5U4C3-1", "name": "Splicing factor, arginine/serine-rich 19", "aln": "MEEEDESRGKTEESGEDRGDGPPDRDPALSPSAFILRAIQQAVGSSLQGDLPNDKDGARCRGLRWRRCCRSPRSEPRSQESGAADTATVLDTAADSFLVELVSILDPPDTWVPSRLDLQPGESEDMLELVAEVRIGDRDPMPLPVPSLFPRLRAWRTGKTVSPQSHASRPACSRH-LTLGTGDGGPAP---PPAPSSASSSPSPSPSSSSP---------------------------------SPPPPPPPPPPPALPAPRFDIYDPFHPTDEAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEE--------GLSQSISRISETLAGIYDDNSLSQDFPGDDSPRREPPPPQTLGAPGTPPQADSTRAEGAPRRRVFVLGPEAEACHEGKVSVEVVT-AGAPALSLPPLPPTDPEIEEGEIVQPEEEPRVAVSLFRAARPRQPPASVATLASVAAPAAPPASAPRAPEGDDFLSLHADSDGE---------GALQVDLGEP---------------PAPPAADARWGGLDLRRKILTQRRERYRQRSASPGP-----------PPARKKARRERQRSG---------------DPAPPDSPS-WEAKKHRSRERKLGSHS--TARRRSRSRSRRRS---RSRSADRRRGG-HRSRSREKRRRRRRSASPPPAASSSSSSRRERHRGKRREGG--KKKKKRSRSRAEKRSGD-LEKLPASVPP-SGS----DRDSRR--RGAVPPSIQDLTDHDLFAIKRTITVGRPDKAE--PRAPSPAPAVSPKREVLYDSEGLSADERGGKS-DKDRRRSGAASSS----------------------------------------------SSSREKGSRRKALDG-------DRGRDRDRSSKKTRPPKDSTPGSGPLPKAPPSSGS--SSSSSSCS-------------------------------------------SRKVKLQSKVAVLIREGVSSTTPAK-----------------DSSSSGLGSIGVKFSRDRESRSPFLK--------------PDERAPAEVAKVAPGSN-----KPKKTKAKAKAGAKKAKGTKGKTKPSKTRKKVRSGGSSTASGGPGSLKKSKADSCSQAASAKGTEETSWSGEERTTKAPSTPPPKVAPPPP------------------------------------ALTPDSQTVDSSCKTPEVSFLPEEASEDTGVRVGAEEEEEEEE-------------------------EEEEEEE---QQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPAARISQLPTLPPPMPWNLPAGVDCTTSGVLALTALLFKMEEANLASRAKAQELIQATNQILSHRK---------PSSTLGVTPAPVPTSLGLPPG--PSSYLLPGSLPIGGCGSTP-----------------PTPTGLAPASDKREGSSSSEGRGDTDKYLKKLHTQERAVEEVKLAIKPYYQKKDITKEEYKDILRKAVHKICHSKSGEINPVKVSNLVRAYVQRYRYFRKHGRKPGDPPGPPRPPKEPGPPDKGGPGLPLPPL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H7N4-1", "uniprot_id": "SFR19_HUMAN", "id": "Q9H7N4-1", "name": "Splicing factor, arginine/serine-rich 19", "aln": "MEEEDESRGKTEESGEDRGDGPPDRDPTLSPSAFILRAIQQAVGSSLQGDLPNDKDGSRCHGLRWRR-CRSPRSEPRSQESGGTDTATVLDMATDSFLAGLVSVLDPPDTWVPSRLDLRPGESEDMLELVAEVRIGDRDPIPLPVPSLLPRLRAWRTGKTVSPQSNSSRPTCARH-LTLGTGDGGPAP---PPAPSSASSSPSPSPSSSSP---------------------------------SPPPPPPPPAPPAPPAPRFDIYDPFHPTDEAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRISETLAGIYDDNSLSQDFPGDESPRPDAQPTQPTPAPGTPPQVDSTRADGAMRRRVFVVGTEAEACREGKVSVEVVT-AGGAALPPPLLPPGDSEIEEGEIVQPEEEPRLALSLFRPGGRAARPTPAASATPTAQPLPQPP-APRAPEGDDFLSLHAESDGE---------GALQVDLGEPA--------------PAPPAADSRWGGLDLRRKILTQRRERYRQRSPSPAPAP--APAAAAGPPTRKKSRRERKRSGEAKEAASS---SSGTQPAPPAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDGSEKAPAPAPPPSGSTSCGDRDSRR--RGAVPPSIQDLTDHDLFAIKRTITVGRLDKSD--PRGPSPAPASSPKREVLYDSEGLSGEERGGKSSQKDRRRSGAASSS----------------------------------------------SSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSSGPPPKPPVSSGSGSSSSSSSCS-------------------------------------------SRKVKLQSKVAVLIREGVSSTTPAK-----------------DAASAGLGSIGVKFSRDRESRSPFLK--------------PDERAPTEMAKAAPGST-----KPKKTKVKAKAGAKKTKGTKGKTKPSKTRKKVRSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAEETSWSGEERAAKVPSTPPPKAAPPPP------------------------------------ALTPDSQTVDSSCKTPEVSFLPEEATEEAGVRGGAEEEEEEEE-------------------------EEEEEEEEEEQQPATTTATSTAAAAPSTAPSAGSTAGDSGAEDGPASRVSQLPTLPPPMPWNLPAGVDCTTSGVLALTALLFKMEEANLASRAKAQELIQATNQILSHRK---------PPSSLGMTPAPVPTSLGLPPG--PSSYLLPGSLPLGGCGSTP-----------------PTPTGLAATSDKREGSSSSEGRGDTDKYLKKLHTQERAVEEVKLAIKPYYQKKDITKEEYKDILRKAVHKICHSKSGEINPVKVSNLVRAYVQRYRYFRKHGRKPGDPPGPPRPPKEPGPPDKGGPGLPLPPL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BBI6-1", "uniprot_id": "A0A8M2BBI6_DANRE", "id": "A0A8M2BBI6-1", "name": "", "aln": "MKMGTDGQAEKDEADVVPGESQTEQSPNEEEEVESKTDRRTLGLRCFQGNRETSEDEPSELGAAAVASSEPVFLVPQLSSHPQFLGCDFDVELTAEVKVDDGASLALLTSVTPNLRYQKPGSFLKEHHLFPPSLRKKRVSTDHFFTSDSFPGLCTSVFETPEQTHLPCSFKNSERIIEMAKSPLPSSPSNSPSSPSSAPSSPSSSPSSSSPGGMGTNYQENEDRGHAGDNNVSKGNGDFVSSTSSSLVPSSVPVPPPSSDPSLHASSSFTHPCNDGQSESLENDIYDPFHPTEGEGERDRPSTEDEDEEVDKYDPFEP---------TGSPVSETEEEKRCFDEENEGGSSIISEGNVKAEKEMEIMEPAGTEAGPPDSTETDAPSSVFNNVPLELSTKCSFKDRMREQGK------IKIQGTDSEHSEIEEGEIVGASERVRERVIERR---REVLLPSSSSPSYLQGGVPKPERILRVLEGDGFVSVRADEEWEREPVASVGVGDLRRKLTSRRKEKFRSCPSSASISPPPTSVLPLPSSSFPGSPPLSTDKGRSRKSSKSSKDRDRRKRKEGRGDKEKRKKRKEEKESGEGKRESKAGDHENRSEKEIKDKDREQRSSRSDSRRRKKRRRSTPEHSSRSHSQNASRHNTHSRRSWSSHSEDRHKDKERERERERNHARDRDRDRWRDDRDRERDRESRRRDERRRDREEDTRRSNSRERVNTRRSRDRRDREKEMVRDRDRDRDRRRDSRPVVPPSIQDLNGSDLFAIKRTITVTTTTTTTTVPNSPPRSQRRSHSRSQSSDKHRKRKKKRRRRSEDEERKDEGSRSRSRPTSLSPPRFGYESDHLSDRPEVDMLSLDGEALDSDYPSLEDSPLLSPPPEPPIPSPKIQSGAPKTSRHHPKKKSRSGKTVGQSESTSSSSSHRPKPKIKNLSSVSPPLSASSGNTNSLQPTASSSTTKRERKTGKEKVGKKDAGRSGRSKKLSGGSRKGKLQSKVSVLVREGVSSTTGNSGKLGLDLLGPGGVVSGASGPSVVGGSIAVVFRRDNESRSPFLKPCSETLALPGRGKDPSKTGKQRNILGPPSSTNQSGLKPKKAKPSSATSTSSSASSPTSSLAAKRRRRPGKKPREKGLTVDGSDSKGANSSCSTVGGGWGGVSTEMQPLIGVGSKPSSPPSAPPGPTPSSSSSSSTSSSASILPPSSSPPHTSPLSLPPSRDTRESSPDSQTVDSSCKTPEPSFLLEDGPVQSKASSLTPSKSPASPPGLLTSQMRGDTISQSTTISKPPPPDDQKASPPCSTSAASLSVISHSSATLANDPSSSSSSSVSSSSVNKPPPPPPPPPSAPPLPWSLQTGVDCTAGGVLALTALLFKMEEANIASRAKAQEFIQATSQILSQANQNQSQPHPSSSSSSVSSQVPPPPSHAPPPGPTPAQFILHSSVPLVGCTKTPPSHLHSGLSMGGGCAQTPPPPGLTGPTGGSETGWDSESK-DPDKYLKKLHTQERAVEEVKLAIKPYYQRKDINKDDYKDILRKAVHKICHSRTGEINPVKVSNLVKLYVQRYKYFRKHGRKMDDEEREDRESASMHSSS-----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: :.:.:.:*:. *:. .::.* . .. : .:**: ..:* . * ... *: .. . . : .. . : * : .*. :**. . .*.. .* . ..* . . :* . .. :.: : :... .:* *.:****.****.******* *. *.. * **. . * :. ..* . : .. . :: ****.** .: . . :.. *:** :: : * ...:*. .* : ::*. ...: .: . : : * . ***.::.. * : * . * . : . ..******** ..*. * : * .. :: : . * *. ***.*:*::*:.: * * *: .* . *.*.:. . .. *: : * *: * *. ::* *:*.:.** : :.: ** ** :: **:*:. * ** . : . ::.:.**:.*.*.:: . .. .*.. :..::*: .:::. **...:* . .: *** ** * .********.. *********** .: *..*. : * .*. *.. .:* :. :::*: .*: * * *.. * ::. .: :.:.**.*.. .:.::..*. **. .. * *.. *:.* *** ******:**:******** . ...* ***.* * **.******** *.: . . .*.*. ****:* .: :.:..: .: .: .:* *:: . . . * .*. .*** ... * .*. . . . **:**. . *.* :************** *** *:.. :: . : .:. . :::: . ..*: :. * ::*: :. **:.*::. *.:. . .. . *. .**:**.* :*****:.****************:********:****.****: : ..*: : .* *.* . *** *:.::* .*:*: ** .** *.*.**. .:. * . .**.: *.**************************:***.*::***************::************: *****:******** .* * . . ... ", "identical_positions": 383, "similar_positions": 411, "identity": "23.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-219", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1A5P0-1", "uniprot_id": "BORG5_RAT", "id": "A1A5P0-1", "name": "Cdc42 effector protein 1", "aln": "MPGPQGGTGAPSMSLGKLSPVGWVPSSHGKRR-----LTADMISPPLGDFRHTMHVGRGGDVFGDTSFLSNHGGR-SGNTHRSPRS--------FLARKLQQVRRVGVPPRRMASPAATSPAPPPISPIIKNAISLPQLNQATYDSLVVSKLSFDSTPASSTDGRSGYGLESGFCTISRLPRVEKHSSRDRDHDRDPDHSQDREQSSSPSEPNPNPELRRSDSLLSFRFDLDLGPSLLSELLGVMSLSEAPAAN-------PPAPAANP-APTAKPPADAVTTLDTVTSLPAP--------------TASSPSSGRFPNGVTAVLGPVAEVKASPVGEGPQVPSKMAFDRR-GASWG-------AIRASRHYTEMDARRELAGVLPQVHGSWESLNEEWSAPPASSRAPVPSTVQANAFEFADADEDDEVKV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91W92-1", "uniprot_id": "BORG5_MOUSE", "id": "Q91W92-1", "name": "Cdc42 effector protein 1", "aln": "MPGPQGGTGAPTMSLGKLSPVGWVSSSHGKRR-----LTADMISPPLGDFRHTMHVGRGGDVFGDTSFLSNHGGR-SGNTHRSPRS--------FLARKLQQVRRVGVPPRRMASPAAPSPAPPPISPIIKNAISLPQLNQATYDSLVMGKLSFDSTPASSTDGHSGYGLESGFCTISRLPRVEKHSNRDR--DRDPDHSQDREQSSFPSEPTPNPELRRSDSLLSFRFDLDLGPSLLSELLGVMSLSEAPAAETPVPTANPPAPAANP-APTAKPPAHAITTLDAVTSLPASAVTSL-----PAPAAASSPSRGHFPNGVTSVLGPAAEAKPSPVGEGPQVPSNMTFDRH-GASWGASRASWGASRASRHYTEMDARRELAGVLPQVHGSWESLNEDWSTPPASVRAPVPTSVQVNAFEFADAEEDDEVKV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q00587-1", "uniprot_id": "BORG5_HUMAN", "id": "Q00587-1", "name": "Cdc42 effector protein 1", "aln": "MPGPQGGRGAATMSLGKLSPVGWVSSSQGKRR-----LTADMISHPLGDFRHTMHVGRGGDVFGDTSFLSNHGGS-SGSTHRSPRS--------FLAKKLQLVRRVGAPPRRMASPPAPSPAPPAISPIIKNAISLPQLNQAAYDSLVVGKLSFDSSPTSSTDGHSSYGLDSGFCTISRLPRSEKPHDRDR-------------DGSFPSEPG----LRRSDSLLSFRLDLDLGPSLLSELLGVMSLPEAPAAETPAPAANPPAPTANPTGPAANPPATTANPPAPAANPSAPAATPTGPAANPPAPAASSTPHGHCPNGVTAGLGPVAEVKSSPVGGGPRGPAGPALGRHWGAGWD----------GGHHYPEMDARQERVEVLPQARASWESLDEEWRAPQAGSRTPVPSTVQANTFEFADAEEDDEVKV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P8I7-1", "uniprot_id": "A0A8M1P8I7_DANRE", "id": "A0A8M1P8I7-1", "name": "", "aln": "------------MSLGKLPAIKGLVSTSQSRRRFKSELSVDMISPPLGDFRHTMHVGRGGDVFGDTSFLSNYGGSGHSDAQRCPDSPPGSKTTRFLSRTLQHVRKTPAPRPRGGSRDFSSP-PPPISPIIKNAISLPQLNLSNGG---LMRTMLHTSTSSPDRPLCSYGLPSGFVTLPRFSRLDQSFAEAP------------ESPRTDSRRSSEVSLSPSDSLSSF--TVDLGPSLMTEVLEIIDN-------------------------------------------------------------------------------SCSLLKSREEEDEDQRSAGSDRENQ-----------------LSDDSVLRSVTADVAIEPRRFQQAASMLARHFGGRAEEERQRPSSFRHTRTPYSFTETEEEIKV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ******..: : *: .** *:.**** **************************:** ..::*.* * **::.** **:. .* * .* .** **.*************** : . : : :.::.:*. ..*** *** *:.*:.* :: . . *. * **** ** :******::*:* ::. . : *. : .: .: . . : : . : *: . *: * . *::.: . :: :: ::*:**", "identical_positions": 107, "similar_positions": 82, "identity": "24.77%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-229", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99MS3-1", "uniprot_id": "MP17L_MOUSE", "id": "Q99MS3-1", "name": "Mpv17-like protein", "aln": "MASWWRAFPQAARRYPWPTNVLLYAGLFSAGDALQQRLRGG-PADWRQTRRVATLAVTFHGNFNYVWLRLLERALPGRAPRTVLAKVLCDQTVGGPIALSAFYVGMSVLQGKDDIFLDLKQKFWNTYKSGLMYWPFVQLTNFSLVPVHWRTAYTGLCAFLWATFLCFSQQSGDGTLQSIFIFLRRK--EASDKSPEK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q2QL34-1", "uniprot_id": "MP17L_HUMAN", "id": "Q2QL34-1", "name": "Mpv17-like protein", "aln": "MAGWWPALSRAARRHPWPTNVLLYGSLVSAGDALQQRLQGR-EANWRQTRRVATLVVTFHANFNYVWLRLLERALPGRAPHALLAKLLCDQVVGAPIAVSAFYVGMSILQGKDDIFLDLKQKFWNTYLSGLMYWPFVQLTNFSLVPVQWRTAYAGVCGFLWATFICFSQQSGDGTFKSAFTILYTKGTSATEGYPKK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IUD3-1", "uniprot_id": "A0A0R4IUD3_DANRE", "id": "A0A0R4IUD3-1", "name": "", "aln": "MRKSFFKRLKRAKILPWISNVTLYGCLFAGGDFVHQCIAQRDEMDWRHTRNVAIVALSFQGNFNYFWLRALESRFPGRSAGMVFRKLVLDQSFASPLATSVFYTGVSFLEGKEDIFEDWREKFFNTYKTGLMYWPFMQFLNFVLMPLYLRTAFMGCSAFVWATFLCFSRQSGDGTAAVALAWVMAPKKRLLHRSTDEEK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : *: ** :** **. *.:.** ::* : :**:**.** :.::*:.****.*** ** :***:. :: *:: ** ...*:* *.**.*:*.*:**:*** * ::**:*** :*******:*: ** *:*: ***: * ..*:****:***:****** : : . ..: ", "identical_positions": 83, "similar_positions": 58, "identity": "41.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-232", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A1K4-1", "uniprot_id": "D4A1K4_RAT", "id": "D4A1K4-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METPIQREIRRSCEREESLRRSRGLS-PGRAGEELIELRVRPVLSRPGSGIPLPRALERAR--AGAKMQRDIEREAHRQAALASP-AVPEPSARPRPQPLDELKRFFEAAA---------------------------------------------------EDGASLQRQPEAGGRLHPALQDGCPVLGQLPPLVAP-----------------------------------------------------------------SLLEQEVLRVRERERELQLQRRSIYGAAEDRE-----------------------------------PAPSLTQS----------RGDGKLAVTWPPRRQASENGLEK----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A087WQ89-1", "uniprot_id": "A0A087WQ89_MOUSE", "id": "A0A087WQ89-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METPIQREIRRSCEREESLRRSRGLS-PGRAGEELIELRVRPVLSRPGSGTPLPRALERAR--AGAKMQRDIEREAHRQAALASP-AVPEPSARRRPQPLDELKRFFEAAA---------------------------------------------------EDGAGLQRQPETGGRLHPAVQDGCPVLGQLPPLVAP-----------------------------------------------------------------SLLEQEVRRVRERERELQLQRRSIYGDAEVQE-----------------------------------PAPSLTPS----------RGDGKLSVIWPPRRRASEKERRP----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96FF7-1", "uniprot_id": "MISP3_HUMAN", "id": "Q96FF7-1", "name": "Uncharacterized protein MISP3", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------METPIEREIRRSCEREESLRRSRGLS-PGRAGRELVELRVRPVLNLPGPGPALPRALERAR--AGAQMQRDIEREAHRQAALARP-AVPEPRARSPPQPLGELKRFFEAAAGSGS-------------------------------------------SAGAGDGAGPQRLPEPGGRPRSAVQGGCRVLGSAPPPFTP-----------------------------------------------------------------SLLEQEVRAVREREQELQRQRRSVYGTAEFKE-----------------------------------PTPSLTAS----------RGDGKLVVIWPPRRKVSENGLEQEERKP-----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QUZ6-1", "uniprot_id": "A0A8M1QUZ6_DANRE", "id": "A0A8M1QUZ6-1", "name": "", "aln": "METDSVTCTQNSESQGERSSAAGKLCFTEDTETTITEDHTDEKKEPQDKNKEEDTEVISGLEKTETPENQFTLEPHDHATSLPEGGATEPTMETVSTNDDQAQEWPPVPGLEEDIQAEENECQATEIQDDVKKNSEASEAVKTMKDIQAGEPVMTTQVDKSTDSPKIPKVTSEEERQELESHGDSDSIVFLSENSEELNIDCKSVDFATTREQWVRRDSRDEVQNVPYSKSSSITETESSSRAQSESKTESGVTAENVQQRELEANNSYCLTENEVMQQVCDEAPPLETFPDRPTNREQENSGCVSMEVKEPLIIPERRRDSESQEREASETGEERKQTQTGGTGGKQLLEVKDQRQERENKGQSAESQSNTKPHQGEGKAKRMQVDHFDDSQSDSGVSADFSPNSTTDEAPQPSESPPYETPIDREIRLALKREQSLRRSRGLCDTTDMTNEFVEIPLRKPILSQDLQIRPSQTLDKDRQFAGKKMQKEISAETEREKVLVELGRLPGFYDKGKEVQLQEKKLLFESFQEQKESMAALRRGSASSYVESAAGILEVDSAVNVRQRLMQFSQNPPTIPVSQYEGSNGNSLAARGPGLTEGIKGQIIIIEASSFPTTAGEPTGYNSASWTDGRSVKVMNSAGVRASSAEPVSARQSTNTQVTEGEGIATENPFFKLRTSVNLHSQVELDIKEAKERERELQKQRSSLYGGATEDPEEARRTRMDSKTESRVKVETGSSSKATLSPPPPPPPQSKLTPSGHQMDVSVRNQSMGKLDLTWPPTLADEQPGQTSEKTLKISRQRNPLLERWESGMVNGHVED", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****:**** : :**:********. . .*::*: :* : . .::*:: * ** :**::*. *:.*: .*. :* : * * * :**: :*:. : . * .::. :: . :. * :* :: .:***:*** ** *:** * * ..** * :. *** : *** .: ", "identical_positions": 63, "similar_positions": 59, "identity": "7.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-238", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q148R9-1", "uniprot_id": "R9BP_MOUSE", "id": "Q148R9-1", "name": "Regulator of G protein signaling 9-binding protein", "aln": "MAREECKALLDALNKTTACYHHLVLTVGGSADTQDLREELQKTRQKARELAVATGARLTVALRDRSLATEERAEFERLWVAFSGCLDLLEADMQRALALGATFPLHAPRRPLVRTGVTGGSSAVAARALSARSLRHEAESDFDVADLPQLEREVLQVGEMIDDMEMKVNVPRWTVQARQAAGAELLSGASAGASSAGGISVEERA------GPCDPSKALAATVFSAVLLVAVALALCVAKLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZC97-1", "uniprot_id": "D3ZC97_RAT", "id": "D3ZC97-1", "name": "", "aln": "MAREECKALLDALNKTTACYHHLVLTVGGSADTQDLREELQKTRQKARELAMATGSRLTVALRDRSLATEERAEFERLWVAFSGCLDLLEADMQRALALGAAFPLHAPRRPLVRTGVAGGSSAVAARALSARSLRHEAESDFDVADLPQLEREVLQVGEMIDNMEMKVNVPRWTVQARQSAGAELLSGASAGASSAGGISVEERA------GPCDPSRALAATVFSAVLLVAVALALCVAKLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZS82-1", "uniprot_id": "R9BP_HUMAN", "id": "Q6ZS82-1", "name": "Regulator of G protein signaling 9-binding protein", "aln": "MAREECKALLDGLNKTTACYHHLVLTVGGSADSQNLRQELQKTRQKAQELAVSTCARLTAVLRDRGLAADERAEFERLWVAFSGCLDLLEADMRRALELGAAFPLHAPRRPLVRTGVAGASSGVAARALSTRSLRLEAEGDFDVADLRELEREVLQVGEMIDNMEMKVNVPRWTVQARQAAGAELLSTVSAGPSSV--VSLQERG------GGCDPRKALAAILFGAVLLAAVALAVCVAKLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BH52-1", "uniprot_id": "A0A8M2BH52_DANRE", "id": "A0A8M2BH52-1", "name": "", "aln": "MGKDECKTMLDALNKVTACYRHLVTALGSTSDSQNLREELKKTRKKAQELAVANRTKLTALLKDKSISKDDRAEYERLWVLFTSSMELLEVDMKRSLEIGQDFPLKVPTRHLIQTGMTGSTTTVAARAMSVQNMKYEADANIDTVDLRELETEIAQVDQMMEEMEMKVQVAPWAVEAKQEAGAELKSTVSVGNSSVGVISICEEEPKETVEGENGTMKIFAGIIFTAVLLIAGILGYLVINL-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.::***::**.***.****:*** ::*.::*:*:**:**:***:**:***::. ::**. *:*:.:: ::***:***** *:..::***.**:*:* :* ***:.* * *::**::*.:: *****:*.:.:: **:.::*..** :** *: **.:*:::*****:*. *:*:*:* ***** * .*.* **. :*: *. * .. : :*. :* **** * *. * :* ", "identical_positions": 111, "similar_positions": 89, "identity": "45.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-239", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0U1RPG8-1", "uniprot_id": "A0A0U1RPG8_MOUSE", "id": "A0A0U1RPG8-1", "name": "", "aln": "MSLPANQIKEPGKQSQPAKSLKEPSQEALPVNLLKESSQESRILCPDPAIVVELNVGGQFYTTTMGTLMKHPGSKFSEILSRSARHYKDAQGRFFIDRPGTYFGLLLDYLRTGQVPTEYVPEVYQEAKFYQIHLLVKILEDMPQIFGEQVARTQFLMGVPNYRENLEVLLHLARAEAVAMRSSKVVVCVVRTEEEDAKCVEPLHILEAKKT--PVVKFGPWKAGPMTEDFVCCLEKDIRAKGYKVTS---QRYHLSR----DPYTC-FWIFVFTWW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BQ13-1", "uniprot_id": "KCD14_HUMAN", "id": "Q9BQ13-1", "name": "BTB/POZ domain-containing protein KCTD14", "aln": "MWQGCAVERPVGRMT---------SQTPLP--------QSPRPRRPTMSTVVELNVGGEFHTTTLGTLRKFPGSKLAEMFSSLAKASTDAEGRFFIDRPSTYFRPILDYLRTGQVPTQHIPEVYREAQFYEIKPLVKLLEDMPQIFGEQVSRKQFLLQVPGYSENLELMVRLARAEAITARKSSVLVCLVETEEQDAYYSEVLCFLQDKKMFKSVVKFGPWKAVLDNSDLMHCLEMDIKAQGYKVFSKFYLTYPTKR----NEFHFNIYSFTFTWW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8RRJ7-1", "uniprot_id": "A0A2R8RRJ7_DANRE", "id": "A0A2R8RRJ7-1", "name": "", "aln": "MSLP--DYKTIGKQS----------SAPVQ----------------SKSQVVHLNIGGHVFSTTLGTIRKFPNSTLAELINGSSKR-MDSEGRYFIDRDGTLFTHILEYLRTEKLPCEHLQEVHKEAIYYDIKPLVKAIEETPQFFGETVGRQQFLARVPNYRENLEVIVRVARAEAIASRHSNIIVCVLRTEDDLSRYNDAIDSLDAPRE--SVVSFGPWKAPASVEDLLDCVKMDIEAKGYKVKI---QAHSVDKGFLFKSYDF-FYKLVFTWW", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : *: : . .: : **.**:**...:**:**: *.*.*.::*::. :: *::**:**** .* * :*:**** ::* ::: **::** :*:*: *** :*: **:*** *.* *** **.* ****:::::*****:: * *.::**::.**:: : : : *: : .**.****** .*:: *:: **.*:**** : .: . : :: :.****", "identical_positions": 91, "similar_positions": 84, "identity": "32.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-249", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K1C9-1", "uniprot_id": "LRC41_MOUSE", "id": "Q8K1C9-1", "name": "Leucine-rich repeat-containing protein 41", "aln": "MAAPEAWRARSCWFCEVAAATTMEATSREAAPAKSSASGPSAPPALFELCGRAVSAHMGVLESGVWALPGPILQSILPLLNIYYLERIEETALKKGLSTQAIWRRLWDELMKTR---PSSLESVTCWRAKFMEAFFSHVLRGTIDVSSDKRLCDQRFSPLLHSSRHVRQLTICNMLQGATELVAEPNRRVLETLASSLHTLKFRHLLFSDVAAQQSLRQLLHQLIHHGAVSQVSLYSWPVPESALFILILTMSAGFWQPGPGSLPCRLCGEASRGRAPSRDEGSLLLGSRRPRRDAAERCAAALMATRRKSEVKQMPRAVPPTRVTRRSTQESLAIGGTDSK--LYLPATSYEASGTKQ-PSAPAAASASSSTSS--KRAPASSASQPKPLKRFKRAAGKKGPRTRQGSGAESEDLYDFVFIVAGEKEDGEEMEIGEVACGALDGSDPSCLGLPALEASQRFRSISTLELFTVPLSTEAALTLCHLLSSWVSLESLTLSYNGLGSNIFRLLDSLRALSGQAGCRLRALHLSDLFSPLPILELTRAIVRALPLLRVLSIRVDHPSQRDNPAVPENAGPPGHIVGDEEIPENCLEQLEMGFPRGAQPAPLLCSVLKASGSLQQLSLDSATFASPQDFGLVLQTLKEHNLSLKRLSFHDMNLADCQSEVLFLLKNLTLQEITFSFCRLFEKR--PVQFLPEMVAAMKGNSTLKGLRLPGNRLGNAGLLALADVFSEDSSSSLCQLDISSNCIKPDGLLEFAKRLERWGRGAFGHLRLFQNWLDQDAVTAREAIRRLRATCHVVSDSWDSTQAFADYVSTM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q15345-2", "uniprot_id": "LRC41_HUMAN", "id": "Q15345-2", "name": "Leucine-rich repeat-containing protein 41", "aln": "MAAPEAWRARSCWFCEVAAATTMEATSREAAPAKSSASGPNAPPALFELCGRAVSAHMGVLESGVWALPGPILQSILPLLNIYYLERIEETALKKGLSTQAIWRRLWDELMKTR---PSSLESVTCWRAKFMEAFFSHVLRGTIDVSSDRRLCDQRFSPLLHSSRHVRQLTICNMLQGATELVAEPNRRVLETLASSLHTLKFRHLLFSDVAAQQSLRQLLHQLIHHGAVSQVSLYSWPVPESALFILILTMSAGFWQPGPGGPPCRLCGEASRGRAPSRDEGSLLLGSRRPRRDAAERCAAALMASRRKSEAKQMPRAAPATRVTRRSTQESLTAGGTDLKRELHPPATSHEAPGTKRSPSAPAATSSASSSTSSYKRAPASSAPQPKPLKRFKRAAGKKGARTRQGPGAESEDLYDFVFIVAGEKEDGEEMEIGEVACGALDGSDPSCLGLPALEASQRFRSISTLELFTVPLSTEAALTLCHLLSSWVSLESLTLSYNGLGSNIFRLLDSLRALSGQAGCRLRALHLSDLFSPLPILELTRAIVRALPLLRVLSIRVDHPSQRDNPGVPGNAGPPSHIIGDEEIPENCLEQLEMGFPRGAQPAPLLCSVLKASGSLQQLSLDSATFASPQDFGLVLQTLKEYNLALKRLSFHDMNLADCQSEVLFLLQNLTLQEITFSFCRLFEKR--PAQFLPEMVAAMKGNSTLKGLRLPGNRLGNAGLLALADVFSEDSSSSLCQLDISSNCIKPDGLLEFAKRLERWGRGAFGHLRLFQNWLDQDAVTAREAIRRLRATCHVVSDSWDSSQAFADYVSTM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I3IS54-1", "uniprot_id": "I3IS54_DANRE", "id": "I3IS54-1", "name": "Leucine-rich repeat-containing protein 41", "aln": "-------------------------------------METTGGNSLLQMCIAKVAQNMDVLERKVLNLPVSLLRDLLPHLNIYYLDRIETAAATKGISTSVIWEKIWKGLDQTWRWKVKSSQSDQSWKQRCLERLFHMLMFTQLKREASYLSNLSDSSVLSITVKHVKVLSLHTSTKNICRLASGDMQPFLSALEKGVTTLKLLES-NSPFKHGRKYLFILHRLLDHGSVRKVVLMRNPE---------------------------------------------------------DSCFLRWLISRR------------------RGPQISVSTEGCGSAVDVFRSGADLEEPAAKR---------------------LALDEEKPEDLCGEFSSSSSSSERCPEG------QIHSLDFEVPN---------------------------------------CEILNMVSHALPTWTCLHTLHVHSDWLISE----------DEMCVFVDSLRRLFLNPAGSLSELSLSHLCG----LTHLINILKACPTLQSLSVDVCLPAERNKWRPLP------------QLPRDKMLSLEKLTVNSTDPMSVQCVLPALALAPELSSLHMTGITLTRHF---FHTLAGCKASLKILKLEDINLSDYHQEILHFLQSSVLEELSFKDCRLLDKCSLKTDFMVAFVEAVKAISSLKTLVLAKNRLATT-AIEISRLFSGCRPSEITTLDLSSNFILPAELLGFAELLETYRPAQRITLDLCFNPLNRDLEVKGQALQKLKPYCNLLMYDWNTRDTMVDHVSVM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ... :*:::* *: :*.*** * ** .:*:.:** ******:*** :* .**:**..**.::*. * :* .* :* .*: : :* :* :: :. .:. . * * : :**: *:: . :. .*.: : .*.:* ..: ***: . * . :. :**:*:.**:* :* * * : * : :** *..* *:: * . :. ..:. * ..:*: * . :*: * ::.... * :* :::.: * *.. . *::.: .*.* :.* *: *.*: * .:: ::**** * :.. * * **.* . * *::* * *: **: * *::*:: ::*.: : .** ..::* .: * : : : : **. : :: .:.* ::** : :** *.:.*:**:* :.*:*.:*:. .*:*::*. ***::* .:*: :* *:*. *:** * *. ***..: : :: :** .*.: **:*** * * ** **: ** : . * * * *::* . :*:::*:. *::: .*:: :::.*:**.*", "identical_positions": 170, "similar_positions": 224, "identity": "20.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-250", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AJW5-1", "uniprot_id": "A2AJW5_MOUSE", "id": "A2AJW5-1", "name": "", "aln": "----MRDCHQKSSINAGSSWNQVQHSKTTSGKRQSGSQGPHVSSQLRSSLLGISQP----AAEKLMETVPTEGIQEQAALSSRYQAASGSK---------------------------------LFLDFHSMEIMKG-ADEDSASDLSDSERVAIPPSPFTPPELNLRAEEIDPVSFSLHPELSQAESRQTYPDFLPPPFNSWDLRDMAVVMNSECRSEALPRATGFLGKYIDRLLQLEWLQVQTVQCEKARAAKAKP---PGASGVLKSPGRGKLLTSALSKPLPSPEGISKSGPSRKKGFRHEEAHPSYYAFETLPNSVDGPGRP----RLCSQKQAPELRME-KKKKSSKGPKLQP----RAPPCAEGNPAMEANGNIRIPRQSAVLLDPVDSHRASRTQAHVDLKKKGSANTCGYAPSSSEKKLKTNGAKQSTYKLK--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NTX9-1", "uniprot_id": "F217B_HUMAN", "id": "Q9NTX9-1", "name": "Protein FAM217B", "aln": "-------------MNAGPSWNKVQHSKNSSGKRQSKSQVPHASSQPRSSLTAVTQP----TEEKLKESISPEARRKRNPLGSRCQGASGNK---------------------------------LFLDFQSMKIIKENADEDSASDLSDSERIPIPPSPLTPPDLNLRAEEIDPVYFDLHPGQGHTKPEYYYPNFLPSPFSSWDLRDMALLLNAENKTEAVPRVGGLLGKYIDRLIQLEWLQVQTVQCEKAKGGKARPPTAPGTSGALKSPGRSKLIASALSKPLPHQEGASKSGPSRKKAFHHEEIHPSHYAFETSPRPIDVLGGT----RFCSQRQTLEMRTEEKKKKSSKSTKLQR----WDLSGSGSSSKVETSGHIRVPKQAAVILDSADSCKASKTQAHAHPRKKGKAESCGHATVSSEKKLKTNGVKQNTYKLK--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5G3-1", "uniprot_id": "A0ACD6B5G3_DANRE", "id": "A0ACD6B5G3-1", "name": "", "aln": "MGTVLQESTVYNSLNLNHSQYKAARHAAASKKTSKAPVLPTPNTSPSSEPVCQQRLRRIRPDTMLIMANPTHRQQSSVKLRSHAASKNGHKDNRKNPGAVKESEGKANSVKSDTVNAEREEPSDCRTEEESCSSRSKAGGDDSASDISDSERYSVLPAKISPPDLDLRAEVIDGPDPLHSFKPTNRVQRSSFPDFLPPPFNSWSLTQLAVYLNTDGKTIPRPKPVGQLERYLDRLLQMEWHQIQTLQEDSSKSAPKHR--HPTPHSSLSAPKCILQCQRAFPLGLLSSMTSLHLSCTHCHNHYSNGSYRQHTRLHTEKRSSGVPQRSSSESRTRSEPRHREHRLSDPLSESRHLRRMQAAGNIRNPVSTCSPEPLSDAGEVKKRRPGRRSQSSVG-AREFGSRVRGRSEQRKTQEDCVLSSAGASDALRGSKESSRLNRKQKRVEFLTQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . * :. : :* * .. . * .:. *. : . * : ... :. * *: . .* * : .* . . ..:*****:***** .: *: ::**:*:**** ** : . :*:***.**.**.* ::*: :*:: :: . *: * * :*:***:*:** *:**:* :.::.. : * . . *.:* *:. * : . :: : . : : .: :.* .. . . * *: : * * . .:* : ::* : . :. *.:: : . .... : ::.: .:: . : * :. .:.. *: . .. : : ", "identical_positions": 72, "similar_positions": 134, "identity": "16.04%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-252", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96LW2-1", "uniprot_id": "KS6R_HUMAN", "id": "Q96LW2-1", "name": "Ribosomal protein S6 kinase-related protein", "aln": "MGAVSCRQGQHTQQGEHTRVAVPHKQGGNIRGPWARGWKSLWTGLGTIR-SDLEELWELRGHHYLHQESLKPAPVLVEKPLPEWPVPQFINLFLPEFPIRPIRGQQQLKILGLVAKGSFGTVLKVLDCTQKAVFAVKVVPKVKVLQRDTVRQCKEEVSIQRQINHPFVHSLGDSWQGKRHLFIMCSYCST-DLYSLWSAVGCFPEASIRLFAAELVLVLCYLHDLGIMHRDVKMENILLDERGHLKLTDFGLSRHVPQGAQAYTICGTLQYMAPEVLSGGPYNHAADWWSLGVLLFSLATGKFPVAAERDHVAMLASVTHSDSEIPASLNQGLSLLLHELLCQNPLHRLRYLHHFQVHPFFRGVAFDPELLQKQPVNFVTETQATQPSSAETMP------FDDFDCD-----------------------LESFLLYPIPA----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "I3ITI6-1", "uniprot_id": "I3ITI6_DANRE", "id": "I3ITI6-1", "name": "", "aln": "MGADASKNSQPYKGSEE------QSQISRWRGFLSAVGIALPAGLCRINPLRVGSHRMICDKEASIPEHLVSSLPGPEKLRMEWSLPSFINMFLPEFPHRIVPGQEHFQVLGYIAKGSFGPILKVKDKSKQKTYAVKVIPKSEILRLGVLEQSKEEVIVQRQVRHPFVHDLQDCWQTQRHIYIMCDYCSTGDLYTYWVMIGQFGEDVVKVFAAELGSALGFLHDCAIIHRDVKMENVLLTDQGHLRLADFGLSRRLERGGRAFTICGTIQYMAPEVLSGGPYNHASDWWSLGILLFALATGKFPVPPEPDHCLMLRRVRSFPYDMPKTFSPSFALLLTELLCKTPARRLRTLERFKRQTFFHGTPFDSHLLQKTPMELILELKNRPDRPAKARRGLTLESFPNFDCDFLLSSPCTPAAQDLSPTLANMERVEALLQSHIPQDDPSQREVFV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** :.::.* : .*. :.* .. ** : :* :** *. : . : .:. * * .: ** **.:*.***:****** * : **:::::** :******.:*** * ::: .:****:** ::*: ..:.*.**** :***:.*****.* *.** :**::***.**** ***: * :* * * :::***** .* :*** .*:********:** ::***:*:******:: :*.:*:*****:****************:******:***:********..* ** ** * ::* ::. .::*** ****:.* :*** *.:*: :.**:*..**..**** *:::: * : .*:: * :**** :*::* ** ", "identical_positions": 194, "similar_positions": 119, "identity": "43.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-253", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A447-1", "uniprot_id": "D4A447_RAT", "id": "D4A447-1", "name": "CD109 antigen", "aln": "---MRNPRLLSAAHLLSVCVVAVAAH-GSRFLVTVPGIIRPGANMTIGVELLQNSPPQVLVKARVLKIASNRSTTVLEAEGVFNRGHFGILVLPALPLHKANKIY--ELHISGKSETEIVFSNRTRLTFDSKRISVFIQTDKVIYKPKQEVKFRVLTLFSDLKP--YKTPVDIYIKDPKSNLIQQWLSQEGELGVVSKTFQLSSHPILGDWSIQVQVIDQLYYQ------------------------SFQVLDYVLPKFEVTLQTP--LYCSLKAKYLRGNVTAKYTYGKPVKGSLSLTFIPLSFWGKKKNITKNFEINGFTNFAFDADEMKKVMNLKKATEISDGNYDQVDPVFPGPVEIVATVTESLTGTSRKASTNVFFKQHDYVIEIFDYT--TVLKPTLNFTATVKISRSDGKQLTPEEMENDLVTVVTQKKNDN-------------------PTREKAQGTD-----------------------YIQMTEYSVPHNGVVKVEFPIMSDSS----ELQLKASFLDSASSVAVHSVFTSPS--------------NTYIQLKTRDEHITVGSPFNLTVSGNQKFKEISYMVISKGQLVAVG------KQSSRTFSLTPEASWAPKACIIVYYIEQDGEVISDILKIPVQLDFKNKIKLSWSKPRVKPSDKVSLRISVTQSYSLVGIVAVDKSVKLIGNSNDITMENVVHELELYN--------TEYYLG-----MFLNS-FAVFQECG---------LWVLTD----ANLVRDNIDEVYDTQEYSERFAEENEANLVDFEDTSSASNSHVRKHFPESWIWLDFYMGSKNHEEYEVTVPDSITSWVASAFVISEDLGFGLTATPAELHAFQPFFISLNLPYSVIRGEEFALEVSIVNYLKDTTKVVVLIEESDS-FDILMFSNDINN-----TIYRKTALVPRENSVTLVFPIKPTHLGNVPITVTAASPTSSDVVTRTIVVKPEGVAKSYSQSVLLELIDKKQQTEPKSLSFSFPPDTISGSERIQITAIGDILGSSINGLSSLIRLPYGCGEQNMVYLAPNVYILDYLTKQKQLTVNLKEKALSFMRQGYQRELLYQREDGSFSAFG-------NSDSSGSTWLSAFVLRCFMEAAQYIDIDQDVLHRTYSWLEAHKKTNGEFWEPGRVIHIELQGGNKSPITLTAYVVTSLLGYKKYQP--NIEIQDSIKFLENEFNRGISDNYTLALVTYALSAVGSPKAEEALTMLTQQAEKEGDTQFWLSSTSESSESWQS-------LSAQIEIAAYALLAHT--QHHVP-EGIPIMKWLIKQRNSLGGFVSTQDTVMALKALSEFSALVYKENRDMQVTIKGPNVPK-PIRFWIDSQNLFKLHKEELAP--LDPIAVNVSAHGSGFAICQLNVDYNVKASSSFKRRRSMENPIGFDLDVDVN-DEHDLRYMKLNVCTSHLGP-----GRTGMALLEVNLLSGFTATSD---SIPLSEILKKVEYEPGK--LNLYLDHVNETQ-FCVKIPTVRDFKVSNIRDGLVSIVDYYEPSRQAVRSYNTQMK--LSSCYLS-ADPN-CRSY------------MDRATDSLRHSSSLLVLCSTLLYFVQH----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R422-1", "uniprot_id": "CD109_MOUSE", "id": "Q8R422-1", "name": "CD109 antigen", "aln": "---MRSRRLLSAAHLLCLCAVALAAP-GSRFLVTAPGIIRPGANVTIGVDLLENSPPQVLVKAQVFKIASNKSRSILEAEGVFHRGHFKTLVLPALPLSSADKIY--ELHINGQSENEIVFSNRTRLTFESKSISVLIQTDKAFYKPKQEVKFRVLTLCSDLKP--YRTSVDIFIKDPKSNVIQQWFSQKGDLGVVSKTFQLSSNPIFGDWSIQVQVNDQQYYQ------------------------SFQVLEYVLPKFEVTVQTP--LYCSLKSKQLNGSVIAKYTYGKPVKGSLSLTFLPLSFWGKKKNITKSFEINGFANFSFDNYEMKKVMNLKPLTDVSEGSYENVDPSFPGPAEIIATVTESLTGISRMASTNVFFKQHDYIIEIFDYT--TVLKPSLNFTATVKVSRSDGNQLTPEEIENDLVTVVTQRKNNH-------------------PESQRDQEMD-----------------------YIQTVNYTIPQNGIIKIEFPVMSISG----ELQLKAYFLDGTSSVTVHSMFTSPS--------------KTYIQLKTRDEYIKVGSPFDLMVSGNRQFKDLSYMVISKGQLVAAG------KQSSRTFSLTPEASWAPKACIIAYYIAEDGEIINDILKIPVQLVFENKVKLFWSKPTVKPSDKVSLRISATQSDSLVGIVAVDKSVTLMENSNSITMETMVHELELYN--------TEYYLG-----MFMNS-FAVFQECG---------LWVLTD----ATLIRDSIDEVYDTEEYSERFAEENEANLVDFEDASSVNNVHVRKNFPETWIWLDAYMGSKIYEEFEVTVPDSITSWVASAFVISEDLGFGLTTVPAELQAFQPFFLFLNLPYSVIRGEEFALEVSIVNYLKDTIKVVILIEESDS-FDILMTSNDTNG-----TIYRKTVQVPRDNGVTLVFPIKPTHLGEIPITVTAASPTASDAVTQTIVVKPEGIEKSYSKSVLLDLTDSNVESKQQSMRFSFPPDTVIGSERVQITAIGDILGSSINGLSSLIRMPYGCGEQNMIYFAPNIYILDYLTKQKQLTVNLKEKALSYMRQGYQRELLYQREDGSFSAFG-------DIDSSGSTWLSAFVLRCFLEADYYIDIDQDVLHRTYTWLNAHKKFNGEFWEPGRVIHSELQGGTKSPVTLTAYIVTSVLGYKKYQP--NIDVQDSIKFLEFEFSRGISDNYTLAIISYALSTVGSPKAEEALNLLMQRSEKEGDTQFWLSSGPALSGSWQP-------RSVDIEIAAYALLAHT--LHHVS-EGIPVMRWLIQQRNSLGGFVSTQDTVVALKALSEFSALVHKENTDIQLTVTGPGIPR-SIHFRIDSQNLFLLHQEELHA--LDPITVNVSAHGSGFAICQLNVDYNVKGSGSSKRRRSTENQEVFDLDVIVN-NEDDISHLNLNVCTSHLGS-----ERTGMVLMEVNLLSGFSASSD---SIPLSETLKKVEYDNGK--LNLYLDSVNESQ-FCVNIPTVRDYKVSNIRDGSVSVMDYYEPRRQAVRSYNTQVK--LSSCYLS-PDTN-CKSH------------TDGATDSLRRSSSLLVFCSVLLYFVQH----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6YHK3-1", "uniprot_id": "CD109_HUMAN", "id": "Q6YHK3-1", "name": "CD109 antigen", "aln": "---MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSADEIY--ELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKP--YKTSLNILIKDPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQ------------------------SFQVSEYVLPKFEVTLQTP--LYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMKNVMDS------SNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYT--TVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEY----------------WSGSNSGNQKME-----------------------AVQKINYTVPQSGTFKIEFPILEDSS----ELQLKAYFLGSKSSMAVHSLFKSPS--------------KTYIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVG------KQNSTMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHELELYN--------TGYYLG-----MFMNS-FAVFQECG---------LWVLTD----ANLTKDYIDGVYDNAEYAERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDK-FDILMTSNEINA-----TGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFG-------NYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQP--NIDVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQP-------RSLDIEVAAYALLSHF--LQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPS-PVKFLIDTHNRLLLQTAELAV--VQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFSGP-----GRSGMALMEVNLLSGFMVPSE---AISLSETVKKVEYDHGK--LNLYLDSVNETQ-FCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVK--LSSCDLC-SDVQGCRPC------------EDGASGSHHHSSVIFIFCFKLLYFMELWL--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UTF1-1", "uniprot_id": "A0A8N7UTF1_DANRE", "id": "A0A8N7UTF1-1", "name": "", "aln": "MEWLQFFGILVCSLVCRGAMVTSSARQNLSYLISVSEVLRCGVPTTLSVTVLSDYPINVTAR------LTHGKTSVAQTQSTVPAGSSRLLSLPPVFYDDMTYWYPYQLNVEGFSGTHLVFSNSTSMVFSPRCMSIFIQTDKNYYQPGQTVKFRVVSVTPDGKP--YSGRTDIFIRDPRGNMIRQWLAVDSFLGVISKELNISQNPPLGSWKITAGVNDVIHER------------------------AFTVDYYVLPRFEVKLDVPSVLYCEDT---LMGTVTAKYFYGKPVSGFMDVRFVHG-FNGIEMRYDHTEMIEGSAEITFDMKDFSTRFND-----YSYSYYDGYRP--IEFIDVNVNITESATGLMYNSSARVSIVTEKYKLEFLQYP--HIVKPSMTFTAKLKLSLYDQRPLSAEDQIESVYLAVTQHKLSPWTWMWSDGGPLGPRMMNNTPSTSFPPNSDGGPLGPHMMNSTPPTSFTPIYDLPVQNIELPVTADGLMSFQIHLSDSVA----TLDLEARFKDTVQHLQLYRSYSSPS--------------KSYIQLH-RDSEPQVGRSLNFTLESSFNLTKIHYLVTSRAGVVDAG------TVQSSSFSLNTDHLWAPQACVMVYYTLPDGEIVNDALHVSFTKVLRNTVSVRWSQDRAEPAESVSLSVSVSEPGSVLGILVVDKATLNSAEDNGLSEKTVLEEFLSYSREM----THTDNRG-----MKMGDPYSVFTACG---------VTVLTD----ARLN----QEMATNQEMFPMFPGE-EGLFMTAMPDSSIQEPRQRKDFPETWIWLDANVSDSASAVFSLTVPDSLTSWAAFAIIMSENLGLGIS-APAELTVFRDFFMSLDLPAFLIRGELLLLEVNLFNYMDVDLEVIVVVAESGM-FEFVSTDSADFS-----VANVRKVLVLSQNFTMLLFPIKATTLGEIPISVKATSVYSSDWLYKTVLVKPEGLQQSFTQTLFLEFL-LQQHTLSRKMTFSFPADVVPNSQRASVSAVGDILGPSIGNLDSLIEMPYGCGEQNMIHFAPNTYVLQYLKSTKQAEEQTRRKAMSYMMEAYERELSYQRVDGSFSAFG-------DSDESGSTWLSAFVLRCFLQARDFISIEPLVMERTAFWLVAHQESDGSFREPGQVIHTELQGGLDGSVSLTAYVLIALLEDAKYESTHKDSVSLALSFLTSRLAQGISSNYSLSLVAYALSLAKSSAAPSALTTLLNRALVIDGVPTWRSPGSVLYDSWQP-------RSADIEIAAYVLLTMH--SLRLMDEGFALMKWLSQQRNHLGGYGSTQDTVMALHALSVYATFSSAESMDLTIRVN-EGSGT-VATFSIDKSNYLLQQSHDLPIESKDGVDIEVEAEGTGFALFQLTVFYNVMNVRRSLRRRDIHTDEAFYLYVDIM--DKEEYHVNLYTCFRLRGGQGL--NQTGMAILDVGLLTGFSLAQD---GVQIDDTVRRVETPSGR--VILYLDKVTTVE-QCIEISTVMDFKVAGVQDAVIMIYDYYEPRRRTVRSYTSERRRDMSVCSFCGSDCSLCGTQG---------FRTDGTPSINNHPLLALSLTTALILLLHIYN--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PDR0-1", "uniprot_id": "M9PDR0_DROME", "id": "M9PDR0-1", "name": "TEP1-F", "aln": "-MRRADAFAVSLCVILALLQTMEPVKAEGKYTIVGPGTIHSHRDYNVAVAVHQTKEPVTLKVG-----ITGPSYNKTETVELATAGEFKQITFKLPPLEAG------EYNLTAEGVKGLEFKNSTKLNWENFKPYIKIQTDKGKYKPGDTINYRVIFLDENLRPDTAKDEVVVWFEDSKRNRIKQEKHIKTTGGVYTGKFELSEFATLGSWSLHVQNGDQHHDGGIYFGGRKQFGGFGHRWHRSDELVNFEVEKYVLPKYSVKMDAT--QQVSVRDGEFNVVLKANYTYGKPVNGKVLVNVHLDSTSSWENVDGKTVQTDYPGHSVVGTADMVGGKAKLTMDLKDFASYLPHKTS-SSYAQITATVEEDFTGVKLNETGGVQLYPYRYEMSCTDYSSCFSFKPDKEHELNFKITYVDGSLITDTKSVVKAKFTEGIRRNYAFYAFG---------TDHQEPELPTIEKKT-----------------------FVFESHLNASGVAPFKVVLPDLPDIANFTRYYSIELEFVDEKRDLYTTYPYREPKQIENPSSEEEKEWFRAEVQRPKDVWNLKIGQEYQVILNSSRPLKYFVYNIVGRGNILETKRVDLAEPQTTVNVTIKPTFLTTPYGRVYFYYVDETGEFRYTEETFSVEVELQNQIEIKAP-AEVKPGADVALEIKTS-PKSFVGLLAVDQSVLLLGSNNDLNKESFNWRLNGYDTSTPWQGGYSYYPGERTGVVTMTNAYFFYNRTAP-------DYNILTEGFGGSSFAMRKTTVAHDSHVFHSGAGGPTQAVGFSAESASASAAPVVRKNFAETWIFADIESTEEEVFKWVKTIPDTITNWVVTGFSLHPQKGLGVTNDQTNIKTFQPFFVSVRLPYSVKRGEVINVPALVFNYLPKTLDVELTLDNEDQEYDFVDASNEVIGD----QKRTQNIRVGANEAAGASFLIRPKVIGNILLKFKAISPLAGDAIHKPLKVVPEGITQYQNRAFFINLKDTGEFKN--TFELEVPEDVVPDSERVEFGLVGDLLGPVVKNLENLLRLPSGCGEQTMSKLVPNYLVRDYLKSIKKLTPALDTRIKRNLQDGYQHMLHYRHDDGSFSSFGPTKWRQEDPVRNGSTWLTAYVLRSFSKIKDIIDLDEQILAKGYEFLLTRQAENGSFTEHGEYFYSSQ----RSLLTLTANSLLALLEEEKPNQ---AAIDKAVAYLSANTAESIEL-LPKSIAIYALQKAKAPEAAKQVASLKSLAKHEDDRTWWTEDLDKLRASKNCGRWWCWIWSQDVEITSYALLSLLDSDQETADSVLNTVRWLIAQRNGFGGFASSQDTVVGLTALIKFAEKSGYEAAKWEVTVSNKGKREKTEKLNTSEENDLLLQTVEFPQG---TKSLEFEAKGTGAAMVQISYQYNLVEK---------EPKPSFKIQTTVL-PESSPANLELSVCVDYVEEGES--KESNMAILEVSLPSGYTADEDSFADIRNIERVRLVETKNGDSVVVIYFENLAKNEEKCIRIEAYRTHAVANQKPSSVVLYDYYDTNKKATEYYSIKSK----LCDICEGDDCKSKC--------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VLY7-1", "uniprot_id": "Q9VLY7_DROME", "id": "Q9VLY7-1", "name": "TEP1-F", "aln": "MRLQGADMGAIPVLILVTACLLCQTSAQGLYSIIAPNTLRPNSQFHVAVSLHNAPESATFKVG-----ILGSSYTDFKTVELRPFS-TQLLHFEIPALRTDR------YRLTAEGLGGVQFTNETQLHFESKQHTVLVQTDKSIYKPGDLVHYRVLILDANLKPARGYGRVHVDIKDSGDNIIRSYKDIRLTNSIYSNELRLSDSPRFGTWSIVVDVSDQEHTQ------------------------TFEILDHILPKFVVDIDTP--KHAIYKDGKIAATVRAHYAFGQPIVGEATLSIYPTFFGSLQPFVNDLITRKVVPIDGNAYFEFD------------IENELHLKQDYERQYLLDALVEEKSTGSVQNYSTVLTLHLNHYRVEAVKVP--SYYIPGVPFEATARIARNDGGQLRDFNPQITAYLTNVYGSSEMYN---------------------------------------------------RTAYSLDASGEIKMKFTVPIGDRDE----FHSIIVDYQGVISEVGKIPSKHLHS--------------KNYITAKVLNDRPTVNQEISVVVRSFAPIKYFMYQVVGRGDIILSRN-VDVAPGTFHTIKFLASFAMMPRANLLVYTVID-GEFVYDEQVIQLEENLLNAVQVDAP-IRAPPGQDIDIGISTK-PYSYVGLMLVDQNANDLRSGHDLTHKRLMDALRSYELSDVN--TPMGSPGKESGVITMSNTDYFIEKEAESNPALDREVSTGPEEDKLTTVRKTDIGPAHKIEVNTLPPGKGRYAFSYTPKPFWHNPRVHVMRDPADTWLFLNISASSDGRNSIHRRIPSEMTSWVVSAFALDPVNGLGLSPPNGKLEAYKEFYISTELPYSIKRDELIAIPFVVHNNRDSDLNVEVTFYNSALDFDFPQLDPKATNQPKVELYRRRSLQVPGRSARSVSFIVTPKRVGPLLVKAMAASSQAGDTVEQNLLVEHPGAMERINRGFLFELNSNAQNRR--NVTIAVPRNAIPESTRIEVSAVGDLIGSLVGNLDSLILLPTGCGEQTMVNFVPNLIVLRYLGRLRQLTPEVELRATNNLAIGYQRILYYRHENGAFSAFG-------LDIKRSSTWLTAYVARSLRQAAPFTQVDSNVLQKALTYLGSVQSANGGFEERGDVFERFG----DDGISLTAFVTLALMENVDLYPEYRNNINKALDFITRGLD-GSSNLHAMAIGTYVLSRANHNAKAAFLQRLDSMATNKDGLKWWNKTAPAGEQQSPWYN---ATRSVNIEISAYAALALL--ENNLVGDALPVLNWLMDQRNPKGGFVASQDTVVGLQALLMFAERFSSQGNNLQIGFHYGEGAE--TIINVNAENSLALQTVELPNN---LKNLSVSATGRGMALAQVSYTYNTNVTS---------AWPRFVLDPTVN-RNSHADYLHLSACASFVSVVGENEQRSNMAVMEVHLPSGFVVDRDTLPTLESSERIKKVETQNRNTKVVIYFDYLDRRE-VCPTLHAYKTVKVTKHRPVAVVMYDYYDSARRARQFYRAPKSNICDICEHANCGDLCEKAEKRESKRPDDYTAIAGHSSGSRHTAIPLASVVMVLSMLLKTLSC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : : . :: :.* : . . . . :: . : : .: . : *.* * : :. : :**** *:* : :::*:: : : :* : :.*. * *:. .: : :.:*. . :* *.: . * : * : ::**:: * ::.. : : *:* :*:*: * : . . : . . :: : . : *. ** : : : * :. . . * . . ::: * : . . . ... . .: : . : . . : :. .. : . :. : * : .:. :: ..: . * . : * **. . . : * :.: . . *. .: : :... . * :*:: **: . .:.:. : . : *. * : : . . . .: : . . :. .::*:: : :*. :*.*.. .: : *:*:: :: .:: *:: ** : *.* : : : * .* : . :. ::: . :. * . * : .. :* : :. * * :.* : : : * * : .: .:::: .. : .* :.: * * .. :**::*. : .* .*: :* *****.* :.** : ** :: : : .*:: * *:: :*:**:** .****:*:* *.: : .:: :: : :* : :* * : * : . ::*** ::: . :. :: :: . . . :: *.*. . : * : .. * . . * ::*:::*. *: . : :.** *** **: ::***.:.* ** :: : . : . : . * : : :: :...* * * *: *:. ** * : : . :.* .* .:.*.:::* * :*: : : : :: ** : :*:: : : * : : *: : : : ***:. ::: . * * . . ", "identical_positions": 155, "similar_positions": 394, "identity": "9.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-27", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H6D3-1", "uniprot_id": "XKR8_HUMAN", "id": "Q9H6D3-1", "name": "XK-related protein 8", "aln": "-MPWSSRGALLRDLVLGVLGTAAFLLDLGTDLWAAVQYALGGRYLWAALVLALLGLASVALQLFSWLWLRADPAGLHGSQP----PRRCLALLHLLQLGYLYRCVQELRQGLLVWQQEEPSEFDLAYADFLALDISMLRLFETFLETAPQLTLVLAIMLQSGRAEYYQWVGICTSFLGISWALLDYHRALRTCLPSKPLLGLGSSVIYFLWNLLLLWPRVLAVALFSALFPSYVALHFLGLWLVLLLWVWLQGTDFMPDPSSEWLYRVTVATILYFSWFNVAEGRTRGRAIIHFAFLLSDSILLVAT---WVTHSSWLPSGIPLQLWLPVGCGCFFLGLALRLVYYHWLHPSCCWKPDPDQVDGARSLLSPEG-YQLPQNRRMTHLAQKFFPKAKDEAAS----PVKG--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C0T0-1", "uniprot_id": "XKR8_MOUSE", "id": "Q8C0T0-1", "name": "XK-related protein 8", "aln": "-MPLSVHHHVALDVVVGLVSILSFLLDLVADLWAVVQYVLLGRYLWAALVLVLLGQASVLLQLFSWLWLTADPTELHHSQL----SRPFLALLHLLQLGYLYRCLHGMHQGLSMCYQEMPSECDLAYADFLSLDISMLKLFESFLEATPQLTLVLAIVLQNGQAEYYQWFGISSSFLGISWALLDYHRSLRTCLPSKPRLGRSSSAIYFLWNLLLLGPRICAIALFSAVFPYYVALHFFSLWLVLLFWIWLQGTNFMPDSKGEWLYRVTMALILYFSWFNVSGGRTRGRAVIHLIFIFSDSVLLVTTS--WVTHGTWLPSGISLLMWVTIGGACFFLGLALRVIYYLWLHPSCSW--DPDLVDGTLGLLSPHRPPKLIYNRRATLLAENFFAKAKARAVLTEEVQLNGVL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F1M2-1", "uniprot_id": "E7F1M2_DANRE", "id": "E7F1M2-1", "name": "XK-related protein", "aln": "MEASSTFHYSFVYYLFTWIGLFLFLLDIVMDIRTVVSLYQEEAYVFMGLMIFFLVGSSVLLQVFSWIWYSDSLDELETEVEKFTKEKKLIKPFHFLQLGVYLRYAGVIEMSTKLFLQQRR---IFKESTFLNLDFQLLGLFETFTESAPQLILMATLMLQRGELQLFSGLKFLASAASIAFTLAMYHNGIRANFDVK---CWTASAIYLLWNILLIITRVAVLALFCSVFPCHIVAHFLSLWMVLVFVAWRQKTDFMESSGWQWLFKATVGLIWYFSWFNISESNTNLNHAVYCIFLLLDMMMLLGFWSWKVTEYAGSWTSLNPTVIIPTILGLYIIGNLVMMMNYKWFYTSYKQKIEELSNKIKEGKIKKVRPLGYRAETETVDKVPGVLLRSRTMAADFYF-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * :. :. ****: *: :.*. *:: .*:: :* :** **:***:* . *. . : : :*:**** * :. . : *: : : ** **:.:* ***:* *::*** *: :::** *. : :. . : :* .*:::* **..:*: : * :*.**:***:**: .*: .:***.::** ::. **:.**:**:: * * *:** .. :**::.*:. * ******:: ..*. . :: *:: * ::*: **. : :.: : :. . :::* : :: * *::.* : . . :. : . . . .: ::: *. ", "identical_positions": 96, "similar_positions": 134, "identity": "23.41%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-38", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48549-1", "uniprot_id": "KCNJ3_HUMAN", "id": "P48549-1", "name": "G protein-activated inward rectifier potassium channel 1", "aln": "MSALRRKFGDDYQVVTTSSSGSGLQPQGPGQDPQQQLVPKKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSVKEQEEMLLMSSPLIAPAITNSK----ERHNSVECLDGLDDITT------------KLPSKLQKITG-----REDFPKKLLRMSSTTSEKAYSLGDLPMKLQRISSVPGNSEEKLVSKTTKMLS----------------DPMSQSVADLPPKLQKMAGGA--------ARMEGNLPAKLRKMNSDRFT-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63250-1", "uniprot_id": "KCNJ3_MOUSE", "id": "P63250-1", "name": "G protein-activated inward rectifier potassium channel 1", "aln": "MSALRRKFGDDYQVVTTSSSGSGLQPQGPGQGPQQQLVPKKKRQRFVDKNGRCNVQHGNLGSETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAYTRGDLNKAHVGNYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAVISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDAKSPFYDLSQRSMQTEQFEVVVILEGIVETTGMTCQARTSYTEDEVLWGHRFFPVISLEEGFFKVDYSQFHATFEVPTPPYSVKEQEEMLLMSSPLIAPAITNSK----ERHNSVECLDGLDDIST------------KLPSKLQKITG-----REDFPKKLLRMSSTTSEKAYSLGDLPMKLQRISSVPGNSEEKLVSKTTKMLS----------------DPMSQSVADLPPKLQKMAGGP--------TRMEGNLPAKLRKMNSDRFT-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F1N1-1", "uniprot_id": "E7F1N1_DANRE", "id": "E7F1N1-1", "name": "G protein-activated inward rectifier potassium channel 1", "aln": "MSALRKKFGDDYQVVTTSSSGGGFNQAAPEK--------KRKRQRFVDKNGRCNVQHGNLGGETSRYLSDLFTTLVDLKWRWNLFIFILTYTVAWLFMASMWWVIAFIRGDMNQAHDDKYTPCVANVYNFPSAFLFFIETEATIGYGYRYITDKCPEGIILFLFQSILGSIVDAFLIGCMFIKMSQPKKRAETLMFSEHAAISMRDGKLTLMFRVGNLRNSHMVSAQIRCKLLKSRQTPEGEFLPLDQLELDVGFSTGADQLFLVSPLTICHVIDSKSPFYDLSLRSMQTEQFEIVVILEGIVETTGMTCQARTSYTEDEVLWGHRFYPVISLEEGFFKVDYSQFHGTFEVPTPPHSVKEQEESLLLSSPLTAPSLCHSAGGVTEGSGTLEGLELQSDAETGSINIATPMPTNKLPAKLQKLTGREVPIRDGMPRKLLRMS---SEITYNLGDLPVKLQRISSAPGVAEERLQPISS-MLSPTEDRLAPKLGLIGGAETISQSVTDLPPKLQRLAGGVGVGGVGIGGRMDGHLPPKLRKMNSERFTGLSLK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*****:***************.*:: .* : *:********************.********************************************: ***:*:** .:*********************************************************************************.**************************************************************************:******** *********:********************************:******************.********:******* **:**** **:: :* * .::* *: .* * ***:****:** *:.:*:****** ** :*.*****:*******.** :**:* . :: *** :.:****:*******::*** **:*:**.*******:*** ", "identical_positions": 413, "similar_positions": 53, "identity": "74.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-39", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N6U8-1", "uniprot_id": "GP161_HUMAN", "id": "Q8N6U8-1", "name": "G protein-coupled receptor 161", "aln": "-----------------MSLNSSLSCRKELSNLTEEEGGEGGVIITQFIAIIVITIFVCLGNLVIVVTLYKKSYLLTLSNKFVFSLTLSNFLLSVLVLPFVVTSSIRREWIFGVVWCNFSALLYLLISSASMLTLGVIAIDRYYAVLYPMVYPMKITGNRAVMALVYIWLHSLIGCLPPLFGWSSVEFDEFKWMCVAAWHREPGYTAFWQIWCALFPFLVMLVCYGFIFRVARVKARKVHCGTVVIVEEDAQRTGRKNSSTSTSSSGSRRNAFQGVVYSANQCKALITILVVLGAFMVTWGPYMVVIASEALWGKSSVSPSLETWATWLSFASAVCHPLIYGLWNKTVRKELLGMCFGDRYYREPFVQRQRTSRLFSISNRITDLGLSPHLTALMAGG-QPLGHSSSTGDTGFSCSQDSGTDMMLLEDYTSDDNPPSHCTCPPKRRSSVTFEDEVEQIKEAAKNSILHVKAEVHKSLDSYAASLAKAIEAEAKINLFGEEALPGVLVTARTVPGGGFGGRRGSRTLVSQRLQLQSIEEGDVLAAEQR-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B2RPY5-1", "uniprot_id": "GP161_MOUSE", "id": "B2RPY5-1", "name": "G protein-coupled receptor 161", "aln": "MDFVQHALLTASRGALTMSLNSSLSYRKELSNLTATEGGEGGAVS-EFIAIIIITVLVCLGNLVIVVTLYKKSYLLTLSNKFVFSLTLSNFLLSVLVLPFVVTSSIRREWIFGVVWCNFSALLYLLISSASMLTLGVIAIDRYYAVLYPMVYPMKITGNRAVMALVYIWLHSLIGCLPPLFGWSSVEFDEFKWMCVAAWHQEPGYTIFWQIWCALFPFLIMLVCYGFIFRVARVKARKVHCGTVVTVEEDSQRSGRKNSSTSTSSSGSRRNALQGVVYSANQCKALITILVVIGAFMVTWGPYMVVITSEALWGKNCVSPTLETWATWLSFTSAICHPLIYGLWNKTVRKELLGMCFGDRYYRESFVQRQRTSRLFSISNRITDLGLSPHLTALMAGG-QSLGHSSSTGDTGFSYSQDSGTDVMLLEDGTSEDNPPQHCTCPPKRRSSVTFEDEVEQIKEAAKNSLLHVKAEVHKSLDSYAASLAKAIEAEAKINLFGEEALPGVLFTARTVPGAGFGGRRGSRTLVNQRLQLQSIKEGNVLAAEQR-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FAM4-1", "uniprot_id": "G161A_DANRE", "id": "E7FAM4-1", "name": "G protein-coupled receptor 161B", "aln": "-------------------MNTS-SNETSLANTTDVE--NRSAWILESVIILAIAVFVCLGNLLVVLTLYRKPYLLTPSNKFVFSLTLSNLLLSVLVLPFVVASSVRGEWLFGVVWCNFSALLYLLISSASMLTLGAIAIDRYYAVLFPMVYPIKITGNRASLAIVYLWLHSLLGCLPPLFGWSTFEFDPFKKTCTVAWYREVSYTAFWVVWCCLVPLSAMLICYGLIFRVARHKARKVHCGTVVIVQSSSNRNGRKNSTASVSSIGSRK----GLIYAGSQCKALVTILVVIGTYLMTWGPYVVVICTEALWGRGSVSSCLETAVSWLSFISAACHPLIYGLWNKTVRKELLGMCCTDHHYRESFVSRHRKNRLFSISNRITDLGMSPHLTAVLAGGGQLLGAGSSTGDTGFSFSQDSGTDTMLLDNYSEGAENSHYSALFNKRRSSVMFEDQVEPQMKGEEES-QQLKAELHQVIDSFASSMAKAIESDAKLQLFSSETQMDRSSSCRAAQ-------RGSRQTDGQRARLQSIDEG--IGADDRDQDHEDDIEEICA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:* * ...*:* * * : .. : : *: *:::******::*:***:*.**** ************:***********:**:* **:*************************.**********:*****:******* :*:**:*****:**********:.*** ** *..**::* .** ** :**.*.*: **:***:****** *********** *:..::*.*****::*.** ***: *::*:..*****:*****:*::::*****:*** :*****:..**. *** .:**** ** ********************* *::***.**.*:*..*************:******::*** * ** .********* ******* ***:: :. : . :.: ****** ***:** :. ::* ::***:*: :**:*:*:*****::**::**..*: . :.*:. **** .** :****.** :.*::* ", "identical_positions": 324, "similar_positions": 125, "identity": "57.86%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-42", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B1WC89-1", "uniprot_id": "B1WC89_RAT", "id": "B1WC89-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------MAQALEDRNPLSEASDEPCESNAPSTPQIRSHSKDYGSLG--------------RYKGQAVADSANLSRERIIPR---------------ALTVSGANGTRRRGALRELLGLQGAAPTGWLSEEH--------------LEFAASGSRRSSGQGSGRVCLE-----------PREHAWILAAAECRFEVLLEMLEVEPRLLMREDPITGYSVLHWLAKHGRHEELILLHDFARRQGLPFDVSAPGSGGLTPLHLAALQGHDMVIKVLVGALGADPSRRDYNGNRPCHYLR--------------------PDASLSLRELSGAEEWEIERDRELENANNNSS---SSTTTTTGWLKCTSSVSRIKSVGINYKEASQSVKEKKAW-------------------------GNQGGQGNGLLRQLFPFTQNR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BY98-1", "uniprot_id": "SWAHD_MOUSE", "id": "Q8BY98-1", "name": "Ankyrin repeat domain-containing protein SOWAHD", "aln": "----------------------------------------------------------------------------------------------------------MAQALEDGNPLPKASNRPAESEAPSDPQI----KDNHCLG--------------RYKVQAVRDSANLSQERIFHS---------------ALTVSGASWARRRGELRELLGLQGAAPAGWLSEEH--------------LEPAVPGSRRSSGQGSSRVCLE-----------PREHAWILAAAECRFEVLLEMLEAEPSLLMREDPITGYSVLHWLAKHGRHEELILLHDFARRRGLPFDVSAPGSGGLTPLHLAALQGHDMVIKVLVGALGADPSRRDHSGNRPCHYLR--------------------PDASLNLRELSGAEEWEIERDRKRENANNNSSRTTTTTTTTSRWLKRTPSASCIKSTGVHYKEASQPVKEKKAS-------------------------STQEGQGRCLRRYLFPFTQNR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NJG2-1", "uniprot_id": "SWAHD_HUMAN", "id": "A6NJG2-1", "name": "Ankyrin repeat domain-containing protein SOWAHD", "aln": "----------------------------------------------------------------------------------------------------------MAQLGGAANRAPTASLAPTSQSLRCAPQPRPSRADTGSLG--------------RYWGKAAAAAS---REHPFPG---------------TLMHSAAGSGRRRGALRELLGLQRAAPAGWLSEER--------------AEELGG----PSGPGSSRLCLE-----------PREHAWILAAAEGRYEVLRELLEAEPELLLRGDPITGYSVLHWLAKHGRHEELILVHDFALRRGLRLDVSAPGSGGLTPLHLAALQGHDMVIKVLVGALGADATRRDHSGHRACHYLR--------------------PDAPWRLRELSGAEEWEMESGSGCTNLNNNSS-------GTTAWR--AASAVGATAVETSRRVAASRTKAKDTA-------------------------GSRVAQMHSLFRHLFPSFQDR---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QL15-1", "uniprot_id": "A0A8M9QL15_DANRE", "id": "A0A8M9QL15-1", "name": "", "aln": "------------------------------------------------------------------------MYEGNCNGAISSNEGHFNAP-------PGAEALPSEEPREETNASGNNANSSDSPKNRIASQFRAHLEERLSRHGP------------RSVSPASSAASSSRRSKLHKPPEGWEPGASRKLSVDASEKGSLTPAMRKKYLKELFLNNGSGLSSILLSKHK-----------SSEEEESAEYGDTLNCGYELWALD-----------PMEHAWMLSAVDGNYDTMLEFLAEDPSLLSRKDFISGFTALHWLAKNGRDETLLQLLRHAEKEGLSVNVNLRGSGGMTALHVAAMHEQYMVVKVLVGAFSANIDVMDYNGKRAWQYLK--------------------EKAPREMKELLG--AWDDEHTVGHLNVNNSAS----------------------QAQPVEEHAQDNKAEVDGSG-------------------------GITRQRFRSFKRLLYSAGLIEKI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "B7Z0B0-1", "uniprot_id": "B7Z0B0_DROME", "id": "B7Z0B0-1", "name": "", "aln": "MELPKELSVAEIRNYMLANECKVTNHALVKHFKKFLTHPQSQNEARKRFKTYVTLLSTIKNENNQKFLILRKKYVNECPTDEVVERAVAAASGIPEPSSPGGASLNFDSPMRQPPPYKPPPMVTSPPAVSIAKEHQENYQECVDEFTAAIKRIEPARLERRTSVKSEDLDQQEKPEKTSRSNSIDVIDNKENIPRFSFSSEASSASSTSIEKPEMADPTAPAAVGDVAENPISVKEATRKFNRMASEEEAKIISPPAKKKPEKQLIEEKDSPEVTLAHPKAKEWIVSMAKANYQELAKMASEYPELVKLQCPATGYTALHWAAKHGNEDVVKLIAG-----TYKADVNARTNGGYTPLHLATQFGRDNIFELLWNVYKANRDIMDWSGNKPLDYSRQRSSVSASTCSSEYAKYFFGADVGNSFRTLGFIESSQITGGTLGSALTRGKKRAQNRFATISGGSLGGVGGAVSRSQSMTVSRRPKKQPGQPISGIFKPATEDGDLLPCEMEGQPVPFRGASTRRKESFLRKTFRATAGGSRRPLAKDVFTNPPEHEIKARKKHAIEKDLGFLRIGSLNVRVKKTTEAFSNFLGVGNGSGVAPTGYGNGGSAVAANRHHPRSHRAPHQRHHHHVGTTRSRHPNQRAAMSTPYATNGGLPSRASVPNSRNIYDGVHKSWGSADNIPHRSEDLMPPPKAVEYISKRNKSSKRSSYASNTTDSPRDSICSSNSSSNLNGGYSSMPTTPNQLRAPKGIAASFAVDSDSDSACGFDSTWSVNCRGSSSSNPSQS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : : * : .: : . *: .. . : .: * . :: * : *::: .. .:: : :: * *: :*::.*** **:*..: : : :*. .** *.**:*: : :.::* .. *: * .*::. .* : .. :: * : ... . : . . . : . : * : ", "identical_positions": 28, "similar_positions": 80, "identity": "3.57%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-44", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3KRC6-1", "uniprot_id": "LRC8E_RAT", "id": "Q3KRC6-1", "name": "Volume-regulated anion channel subunit LRRC8E", "aln": "MIPVAEFKQFT-EQQPAFKVLKPWWDVLAEYLTVAMLMIGVFGCTLQVTQDKIICLPSHESRENSSEAPCQQLLPQG---------ISEQIG-GLRELSGLKNNLDLQQYSFINQLCYETALHWYAKYFPYLVVIHTLIFMVCTSFWFKFPGTSSKIEHFISILGKCFDSPWTTRALSEVSGENHKGPAA-GRATVTTVTTVGTGTGKVGEGEKEKVLIEPEKVVTEPPAVTLLDKKEGEQAKALFEKVKKFRVHVEEGDILYSMYIRQTVLKVCKFFAILVYNLVYVEKISFLVACRVETSEITGYASFCCNHTKAHLFSKLAFCYISFVCVYGITCLYTLYWLFHRPLKEYSFRSVREETGMNDIPDVRNDFAFMLHLIDQYDSLYSKRFAVFLSEVSESRLKQLNLNHEWTPDKLRQKLQRNARGRLELSLCMLPGLPDTVFELSEVEALRLEAICDISFPPGLSQLVNLQELSLLHSPARLPFSSQIFLRDRLKVICVKFEELREVPLWVFGLRGLEELHLEGLFPPEMARGATLESLRELKQLKVLSLRSNAGKVPASVTDVAGHLQRLSLHNDGARLLALNSLKKLAVLRELELVACGLERIPHAIFSLGALQELDLKDNHLRSIEEILSFQHCRKLVILRLWHNQIAYVPEHVRKLRSLEQLYLSHNKLETLPAQLGQCFGLRLLDVSHNGLRSLPPELGLLQSLQHLALSYNALESLPDELFFCHKLRTLLLGYNHLTQFSPHVAALQALSRLELKGNRLEALPEELGDCKGLKKSGLLVEDTLYEGLPAEVREKMEEE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q66JT1-1", "uniprot_id": "LRC8E_MOUSE", "id": "Q66JT1-1", "name": "Volume-regulated anion channel subunit LRRC8E", "aln": "MIPVAEFKQFT-EQQPAFKVLKPWWDVLAEYLTVAMLMIGVFGCTLQVTQDKIICLPSHESRENISGAPCQQLLPQG---------ISEQMG-GLRELSGLKNNLDLQQYSFINQLCYETALHWYAKYFPYLVVIHTLIFMVCTSFWFKFPGTSSKIEHFISILGKCFDSPWTTRALSEVSGENHKGPAS-GRAMVTTVTTTGAGSGKVGEGEKEKVLIEPEKVVSEPPVVTLLDKKEGEQAKALFEKVKKFRVHVEEGDILYSMYIRQTVLKVCKFFAILVYNLIYVEKISFLVACRVETSEITGYASFCCNHTKAHLFSKLAFCYISFVCVYGITCLYTLYWLFHRPLKEYSFRSVREETGMNDIPDVKNDFAFMLHLIDQYDSLYSKRFAVFLSEVSESRLKQLNLNHEWTPEKLRQKLQRNMRGRLELSLCMLPGLPDTVFELSEVEALRLEAICDISFPPGLSQLVNLQELSLLHSPARLPFSSQIFLRDRLKVICVKFEELREVPLWVFGLRGLEELHLEGLFPPEMARGATLESLRELKQLKVLSLRSNAGKVPASVTDVAGHLQRLSLHNDGARLLALNSLKKLAVLRELELVACGLERIPHAIFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSHNKLETLPTQLGQCFGLRLLDLSHNGLRSLPPELGLLQSLQHLALSYNALESLPDELFFCHKLRTLLLGYNHLTQLSPDVAALQALSRLELKGNRLETLPEELGDCKGLKKSGLLVEDTLYEGLPAEVREKMEEE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6NSJ5-1", "uniprot_id": "LRC8E_HUMAN", "id": "Q6NSJ5-1", "name": "Volume-regulated anion channel subunit LRRC8E", "aln": "MIPVAEFKQFT-EQQPAFKVLKPWWDVLAEYLTVAMLMIGVFGCTLQVTQDKIICLPNHELQENLSEAPCQQLLPRG---------IPEQIG-ALQEVKGLKNNLDLQQYSFINQLCYETALHWYAKYFPYLVVIHTLIFMVCTSFWFKFPGTSSKIEHFISILGKCFDSPWTTRALSEVSGENQKGPAATERAAATIVAMAGTGPGKAGEGEKEKVLAEPEKVVTEPPVVTLLDKKEGEQAKALFEKVKKFRMHVEEGDILYTMYIRQTVLKVCKFLAILVYNLVYVEKISFLVACRVETSEVTGYASFCCNHTKAHLFSKLAFCYISFVCIYGLTCIYTLYWLFHRPLKEYSFRSVREETGMGDIPDVKNDFAFMLHLIDQYDSLYSKRFAVFLSEVSESRLKQLNLNHEWTPEKLRQKLQRNAAGRLELALCMLPGLPDTVFELSEVESLRLEAICDITFPPGLSQLVHLQELSLLHSPARLPFSLQVFLRDHLKVMRVKCEELREVPLWVFGLRGLEELHLEGLFPQELARAATLESLRELKQLKVLSLRSNAGKVPASVTDVAGHLQRLSLHNDGARLVALNSLKKLAALRELELVACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELGNCGGLKKAGLLVEDTLYQGLPAEVRDKMEEE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FB32-1", "uniprot_id": "E7FB32_DANRE", "id": "E7FB32-1", "name": "", "aln": "MIPVNEFRNITSEQNPQFRVLKPWWDVLSEYLGIAMLMIGVFGCTLQLTQDKISCLPNRLTDPSGGHTDCSHVRQHRDNQSLWEFSITKYIGPNIVEVFGRKNGLDIHQYEFVNHFCYERAVHWYGKYFPYLVVIHSMIFMVASSFWFKFPGTSSKIELFVVILRKCFDSPWTTRAISEVSEER----MVLWRKNTQSSAPDGGDEEDVLSLIRASIKSDSEQKSTEP---SLLDKKEGEQAKALFEKVRKFRTHVEEADLLYLMYVLQTVLKVFKFVLITVYSVLLVPNIQIVVLCSVPP-DLTGFSAFCCNYNKAHLFSKLAYCYISFVGVYGLLCIYSLYWLFHRPLKEYSFEAVRLETGINDIPDVKNDFAFLLHLSDQYDALFSKRFAIFLSEVSESRLRQLNLNHEWTVGKLRSRLSHNAHERLELHLFMLPGLPETVFEIPEVESLKLELISNITIPSSVTQLPALVELTLIHSPCRLQPAALGHLRDQLKVLRVATESQELLPLWMYTLQNLEELHLSG--------DLTLDSLRELKNLRVLTLRCKLTKIPPGVMDVSQQLLRLCVHNEGTRLQAFSSLKKLVRLAALELTGCGLERIPSAVFSLSHLQELDLRENRLMAVEEILSLQHCRRLATLRLGHNRISCIPEHISRLRALETLDVSWNSLCRLPPRLCYCPRLRHLDLSHNQLVSLPSEIGVLQGLQFLSVAFNALESLPEELFSCRRLRVLALGNNSITALSPRVGNLAQLVRLELKGNRLEGLPVEIADCPALQLTGVIVEDSLMELLPAELKDSMKNR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** **:::* **:* *:*********:*** :*************:***** ***.: . . : *.:: : *.: :* : *: * **.**::**.*:*::*** *:***.**********::****.:************** *: ** ***********:**** *. * . : * . .. . : .: :.*: :** :*****************:*** ****.*:** **: ****** **. * **.:: * :*.::* * * . ::**:::****:.*********:****** :**: *:*:**************.:** ***:.*****:*****:*** ****:*:*****:**********:********* ***.:*.:* **** * ******:****:.***:*:** *.:*::*..::** * **:*:***.** : .***:***: * *. . :***:: *:.******.* **:******:*:**:**.: *:*..* **: :* **.:**:*:** *:.*****. * ***..******* *:***. ******::*:* ::*****:****:*. *** **:*: :***: :**:** * :* *.* **.:* * ** **:*** * ***.*:*:**.**.*::::****:**:*** *::**.* ** * :: :** *. * * ********** ** *:.:* .*: :*::***:* : ****:::.*::.", "identical_positions": 456, "similar_positions": 195, "identity": "56.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-45", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q09428-1", "uniprot_id": "ABCC8_HUMAN", "id": "Q09428-1", "name": "ATP-binding cassette sub-family C member 8", "aln": "----------------MPLAFCGSENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWILTFMLLFVLVCEIAEGILSDG----VTESHHLHLYMPAGMAFMAAVTSVVYYHNIETSNFP----KLLIALLVYWTLAFITKTIKFVKFLDHAIG----FSQLRFCLTGLLVILYGMLLLVEVNVIRVRRYIFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHKKPIDLRAIGKLPIAMRALTNYQRLCEAFDAQVRKDIQG-TQGARAIWQALSHAFGRRLVLSSTFR------ILADLLGFAGPLCIFGIVDHLGKENDVFQPKTQFLGVYFVS-----SQEFLANAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMH-------LSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFRTRVETTRRKEMTSLRAFAIYTSISIFMNTAIPIAAVLITFVGHVSFFKEADFS--PSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPHEPTPQGPASKYQAVP-----LRVVNRKRPAREDCRGLTGPLQSLVPSADGDADNCCVQIMGGYFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLAALGEMQKVSGAVFW-SSLPDSEIGEDPSPERETATDLDIRKRGPVAYASQKPWLLNATVEENIIFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGER----GINLSGGQRQRISVARALYQHANVVFLDDPFSALDIHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVTERKATEPPQGLSRAMSSRD----GLLQDEEEEEEEAAESEEDDNLSSMLHQRAEIPWRACAKYLSSAG-ILLLSLLVFSQLLKHMVLVAIDYWLAKWTDSALTLTP---------AARNCSLSQECTLDQTVYAMVFTVLCSLGIVLCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALAVISYVTPVFLVALLPLAIVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIAAVTSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMELQLGAVKRIHGLLKTEAESYEGLLAPSLIPKN---WPDQGKIQIQNLSVRYDSSLKPVLKHVNALIAPGQKIGICGRTGSGKSSFSLAFFRMVDTFEGHIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPERKCSDSTLWEALEIAQLKLVVKALPGG---------------LDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVIVLKRGAILEFDKPEKLLSRKDSVFASFVRADK-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q09429-1", "uniprot_id": "ABCC8_RAT", "id": "Q09429-1", "name": "ATP-binding cassette sub-family C member 8", "aln": "----------------MPLAFCGTENHSAAYRVDQGVLNNGCFVDALNVVPHVFLLFITFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWILTFILLFVLVCEIAEGILSDG----VTESRHLHLYMPAGMAFMAAITSVVYYHNIETSNFP----KLLIALLIYWTLAFITKTIKFVKFYDHAIG----FSQLRFCLTGLLVILYGMLLLVEVNVIRVRRYVFFKTPREVKPPEDLQDLGVRFLQPFVNLLSKGTYWWMNAFIKTAHKKPIDLRAIGKLPIAMRALTNYQRLCLAFDAQARKDTQS-QQGARAIWRALCHAFGRRLVLSSTFR------ILADLLGFAGPLCIFGIVDHLGKENHVFQPKTQFLGVYFVS-----SQEFLGNAYVLAVLLFLALLLQRTFLQASYYVAIETGINLRGAIQTKIYNKIMH-------LSTSNLSMGEMTAGQICNLVAIDTNQLMWFFFLCPNLWAMPVQIIVGVILLYYILGVSALIGAAVIILLAPVQYFVATKLSQAQRSTLEYSNERLKQTNEMLRGIKLLKLYAWENIFCSRVEKTRRKEMTSLRAFAVYTSISIFMNTAIPIAAVLITFVGHVSFFKESDFS--PSVAFASLSLFHILVTPLFLLSSVVRSTVKALVSVQKLSEFLSSAEIREEQCAPREPAPQGQAGKYQAVP-----LKVVNRKRPAREEVRDLLGPLQRLTPSTDGDADNFCVQIIGGFFTWTPDGIPTLSNITIRIPRGQLTMIVGQVGCGKSSLLLATLGEMQKVSGAVFWNSSLPDSEGEDPSNPERETAADSDARSRGPVAYASQKPWLLNATVEENITFESPFNKQRYKMVIEACSLQPDIDILPHGDQTQIGER----GINLSGGQRQRISVARALYQHTNVVFLDDPFSALDVHLSDHLMQAGILELLRDDKRTVVLVTHKLQYLPHADWIIAMKDGTIQREGTLKDFQRSECQLFEHWKTLMNRQDQELEKETVMERKAPEPSQGLPRAMSSRD----GLLLDEDEEEEEAAESEEDDNLSSVLHQRAKIPWRACTKYLSSAG-ILLLSLLVFSQLLKHMVLVAIDYWLAKWTDSALVLSP---------AARNCSLSQECALDQSVYAMVFTVLCSLGIALCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSILNRFSSDCNTIDQHIPSTLECLSRSTLLCVSALAVISYVTPVFLVALLPLAVVCYFIQKYFRVASRDLQQLDDTTQLPLLSHFAETVEGLTTIRAFRYEARFQQKLLEYTDSNNIASLFLTAANRWLEVRMEYIGACVVLIAAATSISNSLHRELSAGLVGLGLTYALMVSNYLNWMVRNLADMEIQLGAVKRIHTLLKTEAESYEGLLAPSLIPKN---WPDQGKIQIQNLSVRYDSSLKPVLKHVNALISPGQKIGICGRTGSGKSSFSLAFFRMVDMFEGRIIIDGIDIAKLPLHTLRSRLSIILQDPVLFSGTIRFNLDPEKKCSDSTLWEALEIAQLKLVVKALPGG---------------LDAIITEGGENFSQGQRQLFCLARAFVRKTSIFIMDEATASIDMATENILQKVVMTAFADRTVVTIAHRVHTILSADLVMVLKRGAILEFDKPEKLLSQKDSVFASFVRADK-----------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AB32TDX1-1", "uniprot_id": "A0AB32TDX1_DANRE", "id": "A0AB32TDX1-1", "name": "", "aln": "MIYKMMRAYRPTPVSNSTLSFCGSDN-SSAYKVDNGLLNNGCFLDALDVVPHVFLLFSTFPILFIGWGSQSSKVHIHHSTWLHFPGHNLRWLLTAILLFLLVCEIAEGIVSDG----FNQSRHLHLYMPAGLAILAAITSIIYYHNIETSNFP----KLLIALLIYWTLAFVTKTIKFVKYDDHGIG----LRQLRFCITGLLALLYGLMLGVEVNVILRRRYMWFACPTEVKPPDDLQDLGVRFLQPFVNLLSKSTYWWMNTFITSAHQRPIDLKTIGKLPKSMRALSNFQQLRKAFDSQMESGCVH-LQGSGWMWRALRQAFGAPLLLSICFR------FISDLLGFAGPLCISGILQHISRDNHTAPPPVKLLGVHFIS-----SEVFFANAYVLAVLLFLALLLQRTFLQASYYVAIENGINLRGAVQTKIYNKIMR-------LCTSNMSMGDMTTAQICNLVARDTNQLMWFFFLCPNLWAMPVQIVIGVLLLYYLLGASALIGATVITVLAPLQYFVATRLSRAQKSTLEYTSERLKKTNELLRGIKLLKLYAWEHIFRSSVEETRRQELTSLRTFALYTSLSIFMNAAIPIAAVLTIFVVHVHLQSSSDFALSPAVAFGSLSLFHILVTPLFLLSSVLHSTVKALVSVQKLSEFLSSAEIETDQ-DPIAQTPANNNGNIKSVYALQLQAKLVNRKNKAKQDVNRNFEQQDQELRASAQHEDNICIKIVNGYFSWT-QGCPTLTNIDIKVPFGQLTMIVGQVGSGKSSLLLAALGEMQKISGSITW-NSLPRSDSDENIRAHDMSGRQSFTR-RGSVAYASQRPWLLNATVEENILFDTAPNVKRYKDVIEVCQLGPDIDTLPQGDQTVIGERVRHLGIILSGGQRQRISVARALYQQTNVVFLDDPFSALDIHLSDHLMHEGILKFLRQEKRSVVLVTHKLQYLPHADWIIAMRDGTVQTQGTLKDIQCAEPELFEQWRTLMNRQDK--ENSTELKRKSFRRAMMYSRDTVATDDEDEAVADVAVSEVKDSSTSTDEDSLGAELRHRTTIPWSSFATYLKAAG-LFLLPLLIVSQLAKHSLMVAIDFWLAHWTSDVIAAQSES-------AERNCTFTKDCVFSHSWYLQVFCLLCALGIVLCLVTSLAVEWTGLRVAKELHCSLLRIIVLAPMRLFETTPLGNILNRFSTDTNTIDQHIPVTMECLSRSTLLCVSAVGVISYVTPVFLIALLPLTVACYFIQKYFRVASRDLQQLEDSTEMPLLSHYSQTIEGLTTIRAFRHEQRFKKKLLEHTDANNISSLFLTAANRWLEVRMEYIGALVVLIAAVASITNALYRQLSAGLVGLGLTYALMVSNYLNWIVRNLADMEVQLGCVKRVSGLIHTQPESYDNIMTPAQVPAG---WPKYGEIQIQNLSVRYDSSLKPVLKHVSAHIRPGQKVGICGRTGSGKSSFSLALFRMVDTFEGQISIDGIDISKLPLQTLRSKFSIILQDPILFSGTIRFNLDPERKATDEMLWEALEIAQLMPVVKALPGG---------------LDAVVTEGGENFSQGQRQLFCLARAFVRKSSILIMDEATASIDMATESILQKVVMTAFADRTVVTIAHRVHTILGSDVVIVMKHGGIIEYDEPDVLLEQKDSVFSAFVRADK-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38735-1", "uniprot_id": "VMR1_YEAST", "id": "P38735-1", "name": "ABC transporter ATP-binding protein/permease VMR1", "aln": "----------------MGTDPLIIRNNGSFWEVDDFTRLGRTQLLSYYLPLAIIASIGIFALCRSGLSRYVRSAECDLVNEYLFGAQEERKEDNSIERLLRNSNTQANYVNVKKQGRILKLRHFDITTIDVKQIDAKNHGGLTFSRPSTSDHLRKSSEIVLMSLQIIGLSFLRVTKINIELTNRDVTTLLLFWLILLSLSILRVYKRSTNLWAICFTAHTTIWISTWIPIRSVYIGNIDDVPSQIFYIFEFVITSTLQPIKLTSPIKDNSSIIYVRDDHTSPSREHISSILSCITWSWITNFIWEAQKNTIKLKDIWGLSMEDYSIFILKGFTRRNKHINNLTLALFESFKTYLLIGMLWVLVNSIVNLLPTILMKRFLEIVDNPNRSSSCMNLAWLYIIGMFICRLTLAICNSQGQFVSDKICLRIRAILIGEIYAKGLRRRLFTSPKTSSDSDSISANLGTIINLISIDSFKVSELANYLYVTVQAVIMIIVVVGLLFNFLGVSAFAGISIILVMFPLNFLLANLLGKFQKQTLKCTDQRISKLNECLQNIRIVKYFAWERNIINEIKSIRQKELRSLLKKSLVWSVTSFLWFVTPTLVTGVTFAICT-FVQHEDLN--APLAFTTLSLFTLLKTPLDQLSNMLSFINQSKVSLKRISDFLRMDDTEKYNQLTISPD-------------------------------KNKIEFKNATLTWNENDSDMNAFKLCG---------------LNIKFQIGKLNLILGSTGSGKSALLLGLLGELNLISGSIIVPSLEPKHDLIPDCEGLTN-----------SFAYCSQSAWLLNDTVKNNIIFDNFYNEDRYNKVIDACGLKRDLEILPAGDLTEIGEK----GITLSGGQKQRISLARAVYSSAKHVLLDDCLSAVDSHTAVWIYENCITGPLMKNRTCILVTHNVSLTLRNAHFAIVLENGKVKNQGTITELQ-SKGLFKEKYVQLSSRDSINEKNANRLKAPRKNDSQKIEPVTENIN--------------FDANFVNDGQLIEEEEKSNGAISPDVYKWYLKFFGGFKALTALFALYITAQILFISQSWWIRHWVNDTNVRINAPGFAMDTLPLKGMTDSSKNKHNAFYYLTVYFLIGIIQAMLGGFKTMMTFLSGMRASRKIFNNLLDLVLHAQIRFFDVTPVGRIMNRFSKDIEGVDQELIPYLEVTIFCLIQCASIIFLITVITPRFLTVAVIVFVLYFFVGKWYLTASRELKRLDSITKSPIFQHFSETLVGVCTIRAFGDERRFILENMNKIDQNNRAFFYLSVTVKWFSFRVDMIGAFIVLASGSFILLNIAN--IDSGLAGISLTYAILFTDGALWLVRLYSTFEMNMNSVERLKEYSSIEQENYLGHDEGRILLLNEPSWPKDGEIEIENLSLRYAPNLPPVIRNVSFKVDPQSKIGIVGRTGAGKSTIITALFRLLEPITGCIKIDGQDISKIDLVTLRRSITIIPQDPILFAGTIKSNVDPYDEYDEKKIFKALSQVNLISSHEFEEVLNSEERFNSTHNKFLNLHTEIAEGGLNLSQGERQLLFIARSLLREPKIILLDEATSSIDYDSDHLIQGIIRSEFNKSTILTIAHRLRSVIDYDRIIVMDAGEVKEYDRPSELLKDERGIFYSMCRDSGGLELLKQIAKQSSKMMK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: :.**: . : : : :: : *.: * . ... . . * .:: * . : :: .: . :. . : :*:.: : * . : : . .**:. :::: * *:*: * :: :: : : : :.:: * . . * . . :: * . :::*: ::: * :::. : . :. * :: . * : : . : :: :: :* . :. :: . * : *: . : *:: : .. * : . : *. : *:: : :*:. * . . :*: : :.:*. : :** * :: :*: . . . . * **:: *: :: : : *:: * **: :**.**: * ::* :: *:::::*. *.: *:.**: :.:*:.: ** *:.*:::* :***. : . :: *::*: ** :: *:: *: . * .. *. . : . *: ..:** :**** :* *** **.:: :: **::::*:** : . : . . : . * ..:: . : *:. *:*.:*:*..*.***:***. ***:: :**:: . * : ..**.** .**** **::** *:. * .**: **:.* * *:: ** ** * ***: ** *****:****:***:*. :: *:*** :**:* * : : . * * .:: :::. : * :*.: *.:.:*.:: :**:.::* :: : *:: * .*:. :: . : . . : :: : : : : . *. **. * : *. *. : : :::: .:*: :*.... . . :. : :.. . * *: :: : * ..:: . :*::.::.:. .** :: * :*:*:.**:* *:****.* : :**.: :* . : *.* : :*: :** ** . : : : :*: *:: .***:*::*:. *: *::.*:::*: *: ***** * ** : :: * ** : ::*:.: :*:..*:: *** :** :. : * :.:**.*:.****::.:: *:** : :*:::..*:*: : *.* . : . **. *:*:*:***:** ..* **:::*. : * .*:** ****:***:: *:**::: : * * *** **:*: * *** ::** ***:**:***: *:** : :. :::**. .:* : *.: ::*** *:***:***: :**:::*:..*:::****:*** :: ::* :: : * . *::*****:::::. * ::*:. * : *:*.*. **. : .:* :: * . ", "identical_positions": 354, "similar_positions": 546, "identity": "20.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-48", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0B4KH28-1", "uniprot_id": "A0A0B4KH28_DROME", "id": "A0A0B4KH28-1", "name": "", "aln": "MSHHSDDQ-LLQAGSDSFWEPGNYKRTTKRIEDGYKLCNDLQQLIQERADIEKGYAKSLRTWSKKWGELIEKGPEYGTTEAAWKGVLTESERISDVHMKIKDNLCNDVNSQIKTWQKENYHHTLMQ-IKERKDLEDLFKKAQKPWAKLLAKVEKAKADYHSACKTERSATNQERNANADSSLSPDQVKKMHDRVQKTKDQVQKCREKYEQAIAEITKYNSVYIEDMTSVFEKCQTFEKTRLQFFKEILFNVHSCLDLTKVQSLPQIYEEFSHTINNADQQKDLKWWSNNHGINMAMNWPSFVEYTEEFRDIAKGNKSKEALPAAPITLINQRPVAEDVHQEYPQTNSLKKNTSTLSSVSSRASVKSEIATTQSSVTTSEAKTSAAVAGAATATAAATAASAASNRNSSVTNGNGKVDANPFDEEEEWDESDNVLVDNGEPGVPVKALYDYEGAESDELTFKQGDVFEKLEDEDEQGWCKGRMNG-RVGLYPANYVETA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "F1R2D9-1", "uniprot_id": "F1R2D9_DANRE", "id": "F1R2D9-1", "name": "", "aln": "MSTLPAESGPEDANNQSFWMPGNYHQTVKRTEDSFQACNDIVACFQERARVERQYAQQLSEWSAKWKPLVDASPLYGSLLRAWQCFLSSADRLSSLHSSICRALVSEDGDRIRTWQKETFHKKIFGGFKESQDFETGFSRAQKPWAKRLKKLEKARSAFHKACRKEHMARERETHAQGNPDIAIEKQRKIQEETELAHQETEKVRARYEKVLEEVTRYAPRYMEEMESIFDQSQEEERKRISFLKQAFLSIHRHLDVTNNESVKAVYNELHDTLMSISEQEDLRWWKNTHGPGMPTDWPQFQEWTPDK----KHKKGKK-----------------------------------------------------------EVEQKAAVM------------------ERSVMIG----------------------------GVRVRALYDYVGQETDELSFKAGEEFLKIEDEDDQGWCRGMMDGGKEGLYPANYVEAV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . :. :*..:*** ****::*.** **.:: ***: :**** :*: **:.* ** ** *:: .* **: **: .*:.::*:*.:* .* * .: ..:*:*****.:*:.:: :** :*:* *.:******* * *:***:: :*.**:.*: * ::* :*:.:..:: :: :*:::..: ::::.:* * :**:.: *:*:* . *:*:* *:*::.* *:.*:.*:*: ::.:* **:*: :*: :*:*: .*: . .:*:**:**.*.** .*. :**.* *:* : * :*.*: *.: .*** : ** * ** *:***** * *:***:** *: * *:****:****:* *:* : *********:.", "identical_positions": 161, "similar_positions": 146, "identity": "32.33%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-49", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LQX4-1", "uniprot_id": "RHG44_RAT", "id": "F1LQX4-1", "name": "Rho GTPase-activating protein 44", "aln": "MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKR-----SKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDELAQELIHFELRVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMDSSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRDQLSADMYSFVAKEIDYANYFQTLIEVQAEYHRKSLTLLQAVLPQIKAQQEAWVEKPSFGKPLEEHLMISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD--VQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNIQEQDKRLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWP---QSEGNITEMMTTVSLQIVG--IIEPIIQHADWFFPGEIEFNITGSYGSPVHVNHNANYSSMPSPDMDPADRRQ-PEQARRPLSVATDNMMLEFYKKDGLRKIQSMGVRVMDTSWVARRGSSAG-RKAACAPPSMQPPAPPSE----------LAAPLPSPLP-------------------------EQVP--------------------------------DSPATPAPALSPSGAS-----------LQPTPERPSVSKSKELS-------------------------------------------------------------------PGSGQKGSP-----------GSIQGTTCPGTQLGPQP------AASPSQLPADQSPHTLRKVSKKLAPIPPKVPFVQPGTVSDQPTGQPSPVSLSPTPPSTPSPYGLSYPPGYSMAS--GQLSPASAPPLASP-SVFTSTLAKSRPTPKPRQRPTLPPPQPPSVSLSASSPQSTEHPMLDGMSPGESMST-DLVHFDVPSIHIELG---STLRLSPLEHARRHSVTDKRD--SEEESESTAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SSM3-1", "uniprot_id": "RHG44_MOUSE", "id": "Q5SSM3-1", "name": "Rho GTPase-activating protein 44", "aln": "MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKR-----SKKLPLTTLAQCLVEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMDSSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRDQLSADMYSFVAKEIDYANYFQTLIEVQAEYHRKSLTLLQAVLPQIKAQQEAWVEKPSFGKPLEEHLMISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD--VQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNIQEQDKRLQALWNACEKLPKANHNNIKYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWP---QSEGNITEMMTTVSLQIVG--IIEPIIQHADWFFPGEIEFNLTGSYGSPVHVNHNANYSSMPSPDMDPADRRQ-PEQARRPLSVATDNMMLEFYKKDGLRKIQSMGVRVMDTSWVARRGSSAG-RKASCAPPSMQPPAPPSE----------LAAPLPSPLP-------------------------EQVP--------------------------------DSPATPAPALSPSGAS-----------LQPTPERPSVSKSKELS-------------------------------------------------------------------PGSGQKGSP-----------GSIQGTPCPGTQLGPQP------AASPSQLPADQSPHTLRKVSKKVAPIPPKVPFVQPGTVSDQPVGQPSPVSLSPTPPSTPSPYGLSYPPGYSMAS--GQLSPASAPPLASP-SVFTSTLAKSRPTPKPRQRPTLPPPQPPSVSLSASSPQSTEHPMLDGMSPGESMST-DLVHFDVPSIHIELG---STLRLSPLEHARRHSATDKRD--SEEESESTAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q17R89-1", "uniprot_id": "RHG44_HUMAN", "id": "Q17R89-1", "name": "Rho GTPase-activating protein 44", "aln": "MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLELVKQVSHSTHKKLTACLQGQQGAEADKR-----SKKLPLTTLAQCLMEGSAILGDDTLLGKMLKLCGETEDKLAQELIHFELQVERDVIEPLFLLAEVEIPNIQKQRKHLAKLVLDMDSSRTRWQQTSKSSGLSSSLQPAGAKADALREEMEEAANRVEICRDQLSADMYSFVAKEIDYANYFQTLIEVQAEYHRKSLTLLQAVLPQIKAQQEAWVEKPSFGKPLEEHLTISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKAALDCCVVD--VQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNVQEQDKKLQALWNACEKLPKANHNNIRYLIKFLSKLSEYQDVNKMTPSNMAIVLGPNLLWP---QAEGNITEMMTTVSLQIVG--IIEPIIQHADWFFPGEIEFNITGNYGSPVHVNHNANYSSMPSPDMDPADRRQ-PEQARRPLSVATDNMMLEFYKKDGLRKIQSMGVRVMDTNWVARRGSSAG-RKVSCAPPSMQPPAPPAE----------LAAPLPSPLP-------------------------EQPL--------------------------------DSPA--APALSPSGLG-----------LQPGPERTSTTKSKELS-------------------------------------------------------------------PGSAQKGSP-----------GSSQGTACAGTQPGAQPGAQPGASPSPSQPPADQSPHTLRKVSKKLAPIPPKVPFGQPGAMADQSAGQPSPVSLSPTPPSTPSPYGLSYPQGYSLAS--GQLSPAAAPPLASP-SVFTSTLSKSRPTPKPRQRPTLPPPQPPTVNLSASSPQSTEAPMLDGMSPGESMST-DLVHFDIPSIHIELG---STLRLSPLEHMRRHSVTDKRD--SEEESESTAL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q151-1", "uniprot_id": "A0A8M9Q151_DANRE", "id": "A0A8M9Q151-1", "name": "Rho GTPase-activating protein 44", "aln": "MKKQFNRMRQLANQTVGRAEKTEVLSEDLLQVEKRLDLVKQVSHSTHKKLTACLQGQQGTEIEKRSVKSPSKKLPLTTLAQCMVEGAAVLGDDSLLGKMLKLCGDTEEKLAQELLVFELQIERDVVEPLYVLAEVEIPNIQKQRKHLAKLVLDMDSARTRWQQSSKSSGHPSNVQQGGAKSDSLREEMEETANRMEICRDQLSADMYNFVAKEIDYANYFQTLIEVQAEYHRKSLEILQSVLPQIKAHQEAWIEKPSYGKALEEHLAISGREIAFPIEACVTMLLECGMQEEGLFRVAPSASKLKKLKASLDCGVMD--VQEYSADPHAIAGALKSYLRELPEPLMTFELYDEWIQASNIQDMDKRLQALLCTCEKLPADNLNNFRYLIKFLSKLTEYQDSNKMTPGNIAIVLGPNLLWT---HSEGNMTEMMTTMSLQIVG--IIEPIIQHADWFFPGEIEFNLTGSYGSPVHTNHNSNYSSMPSPDMDQSERKQQHDQSRRPLSVATDNMMLEFYKKDGIRKIQSVGVRVMDTSWVKGKSTSTLSRKSSSTPPSGQPPGSPADTLISEQAGELATSPIPTPPPGDRGSSDDVSPNRPDSSHVYVSHVEERPPPPYPSSSSHPGPHHFYPKPPPCARPVAPGPESQPPASPPPPLRWSGFAPPQPPHQPQHQHQPQPQLPPPSSSSSSSSSSLDINSNPKPSCLHFPKHGPVCDAPHASMLHDVNSSPLYIKTPLVLTRHDPPSLPSSAPPPWAACPCARERGPPRLTSTLKSKELSPVIGHKAVQASGSTVPPVGGQQSNSQSPHSAEHSPHTLRKVSKKLAPVPPKVPYGQSGGMSDQSTGQPSPVSLSPTPPSTPSPYGLSCPPGHAPTSSPGQTPLGGPHTLSSPPTSLTGTLTKSRPTPKPRQRPSLPPPQPPTVPP--TVPQPLEQGLLDGLSPGESMSTADFFSLEIPSINVNLDSLLDEFRVVPCRSSLAAVSSPEGDSVSEEEGQSTTL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VDS5-1", "uniprot_id": "RG92B_DROME", "id": "Q9VDS5-1", "name": "Rho GTPase-activating protein 92B", "aln": "MKRQFAKIKIAAEN-LSRSSKSDSKDSELEAIERQVDRYRDTIEKIVRKLPALSGGGGSGSGSSEEQDKRTKKNSHYKIAQALDESAKELPKDMPLQKVLANCGELEKTMAECIIESELETEAKVVRRLKNILDKEIQEISTLKRNVSRTLQEYTSLKRSHEAAIR-------LEEPAAKVNHIKSQQEECELKLEKERDAWAAQMLELIAKEDEIVSCIRDYVLNQRNYHERALQHVNASLARIQDTIQG-TEKSRFGTSLKEHLTSTNREISYIVELCCCCLLEHGLEEEGLLRVGCASTKLRRMKHALEAQHVKTPLPLDYQDPHVIGSILKLYLRELPEPLLTYNLYKDFIRIAERHSEAERKTEIKAILTKLPKENYANLRYLTRFLSIVQQRSALNKMSSQNLAIVMSPNMLWPRIDKSSNAPADYIGQVNSSSAANIIVELLISQWDYFFIGEVEFYLTLQKQKLFVEGKSKSNSSNENLDRNDSEVME-----------SPRYGTLRRQKANAPSPPTTNGNGIIMTTSQTSHRPHAK---------ELFPQQTPEK----------QEKPAKPPLP-------------------------------------------------------------NLPQFQSPAASQPTQTQLEP-------LPPPPVTPAKPVP---------------------------------------------------------------------------------------------MTRTQFFGLDNLPSP--------TADRKSTDSIGSFKLKPDVPQKPLLPKRPTVLGVGVPKADGKSDDEGGTTPTQATIDNGNGSVRFKTEHFLDKLRQENGETNGTREVSSTTKENNHNHDPPATAADQNQQQAQPQ-VTTPISPNSFQTPKRPTVPAPPPPTNWKSSD--------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:** ::: *:: :.*:.*:: ..:* :*:::: ::. .. :**.* * . . ... :** . .:**.: *.: * .* * *:* **: *. :*: :: **. * .*:. * : : ** :*.. :::::: : : * : : : : :: .** : ::.: ** ::* ** :*:* .::*** : .. :: : * :**.::* ::: *.:*: :. **. :*..*:*** :.***:: :* * *** *::****:**. :::**:::* :*:. :. : ***.*.. ** *********:*::**.::*: :: :. :: : *** * *::** :*** : : . ***:. *:***:.**:**. ::.. :: : :. . .. *:* :*.: *:** **:** :* . . . .:. . ** . * : :: : :. *. * :. : * :: *. : . : . * .* . * .* * : * .*. . * * .. . . . . * : . .:: * . *: ** * :.. . . . :** .: . * . * . . : .. :. *:. . *. . ** :. . *. : : . .* . .: * ", "identical_positions": 164, "similar_positions": 256, "identity": "16.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-55", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9QX74-1", "uniprot_id": "SHAN2_RAT", "id": "Q9QX74-1", "name": "SH3 and multiple ankyrin repeat domains protein 2", "aln": "------------------------------------------------------MKSLLNAFTKKEVPFREAPAYSN-------------RRRRPP--------NTLAAPRVLLRSNSDNNLNAG-------APEWAVCSAATSHRSLSPQLLQQTPSK-PDG---ATKSLGSYAPGPRSRSP-----------------------------------------SLNRLGGAGEDGKRPQPPHWHVG-SPFTPG-------------------------------------ANKDSLSTFEYPGPRRK---------LYSAVPG-------------------------------------------------------------------------------------RLFVAIKPYQPQVD-----------------------------GEIPLHR----------------------------------GDRVKVLSIGEG--GFWEGSAR--------GHIGWFPAECVEEVQCKPRDSQ-----------------------------------AETRADRS--KKLFRHYTVGSYDSFDAASDCIIEDKTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAG--LRTGDFLIEVNNENVVKVGHRQVVNMIRQGGNHLVLKVVTVTRNLD-PDDTARKKAP---------------PPPKRAPTTALTLRSKSMTAELEELGLSLVDKASVRKKKDKPEEIVPASKPSRTAENVAIESRVATIKQRPTSRCFPAASDVNSVYERQGIAVMTPTVPGSPKGPFLGLPRGTMRRQKSIDSRIFLSGITEEERQFLAPPMLKFTRSLSMPDTSEDIPPPPQSVPPSPPP--PSPTTYNCPRSPTPRVYGTIKPAFNQNPVAKVPPATRSDTVATMMREKGMFYRRELDRFSLDSEDVYSRSPAPQAAFRTKRGQMPENPYSEVGKIASKAVYVPAKPARRKGMLVKQSNVEDSPEKTCSIPIPTIIVKEPSTSSSGKSSQGSSMEIDP--QATEP-GQLRPDDSLTVSSPFAAAIAGAVRDREKRLEARRNSPAFLS------------TDLGDEDVGLGPPAPRMQ--------PSKFPEEGGFGDEDETEQPLLPTPGAAPRELENHFLGGGEAGAQGEAGGPLSSTSKAKGPESGPAAALKSSSPASPENYVHPLTGRLLDPSSPLALALSARDRAMQE----SQQGHKGEAPKADLNKPLYIDTKMR---PSVESGFPPVTRQN---TRGPLR-RQETENKYETDLSKDRRADDKKNMLINIVDTAQQKSAGLLMVHTVDIPVAGPPLEEEEDREDGDTKPDHSPSTVPEG---VPKTEGALQISAAPEPAAAPGRTIVAAGSVEEAVILPFRIPPPPLASVDLDEDFLFTEPLPPPLEFANSFDIPDDRAASVPALADLVKQKKSD-------TPQPPSLNSSQPANSTDSKKPAGISNCLPSSFLPPPESFDAVTDSGIEEVD-------SRSSS-DHHLETTSTIST-----VSSISTLSSEGGESMDTCTVYADGQAFVVDKPPVPPKPKMKPIVH---KSNALYQDTLPEEDTDGFVIPPPAPPPPPGSAQAGVAKVIQPRTSKLWGDVTEVKSPILS--GPKANVISELNSILQQMNRGKSV------KPGEGLELPVGAKSANLAPRSPEVMSTVSGTRSTTVTFTVRPGTSQPITLQSRPPDYESRTSGPRR---------------APSPVVSPTELSKEILPTPPSAAAASPSPTLSDVFSLPS--QSPAGDLFGLNPAGRSRSPSPSILQQPISNKPFTTKPVHLWTKPDVADWLESLNLG---------EHKETFMDNEIDGSHLPNLQKEDLIDLGVTRVG----------HRMNIERALKQLLDR---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AC58HV42-1", "uniprot_id": "A0AC58HV42_DANRE", "id": "A0AC58HV42-1", "name": "", "aln": "MCVYVYVCVCVCVCVCVCVCVCVCVCVCVCVCVCVSVCVCVCVCCSGAAEVLTMPRSPTSSEDEMAQSFSDSSQDSSSESSREEAVYERVRAERPVSRMMDIQSNTLMVQVFIPDLQQTKCLRFDPCASVWAAKQRILCTLSQNLKDVLNFGLFQPSSS-GDGGFLEEESLMGDLPVPAGESLPMLEFRYKTRLYSQSSVDEKQIARLHTKANLRRFMDCILHRQLEKVSRMLDKGLDPNYQDSESGEAPLTLAVQMESMVEFIKALRNGGAHLDFRAKDGMTALHKAACAKNQDALKTLLDLGASPNSKDSRGLTALYHTVTAGGETHCCELLLDANTALCCQDENGWQETHQACRHGYVEHLEHLLCYGADMSAQNASGNTPLHICALYNQEKCAHVLLLRGADKDMKNYSSQSPFQVALISGNFELAELIKNHRDPEPVGLSDTPSASRGRRPLPRSGVCMSRSLLRSSSDINVPERTVSPELQQMQRDAGARMRMMMMTSGRSGRMKSNSRSLSVSLEDEHSSSTTLKCPNGRVCVPSSRRKLYSATSGRHVLLVRSCLPHAGGGENSSLHRNGRVRDSRAERSDRKKLFRHFTVGSYDSMDNSSDCTTEQKTVVLQKQDSEGFGFVLRGAKADTPIEEFIPTAAFPALQYLESVDEGGVAWLMG--LRTGDFLTEVNHQSVVKMGHRQVVSMIKHGGNRLVIKVVRVSRNPDDKDDKTRKKAP---------------PPPKRAPTTALTMRSKSMTCELEDP--------------DKVEEAVPPQK---IMHEKSSADKTVSIRSRPSSRFLASMDFNQSASERPGVAVVPPNVPGRSHGGYIRLPKSSMRRQKSVG-------IAGEEKKFLIPPLLKFSRSLSMPDTSEDIPPPPGISPPSPP--------YKLSTS-TAQGYEPNQSIYTQNSAARCH---------TIERDQVGYHRQNFEPYDCQTHPGLN------------RAHVPENPYSD------KPLYVPPKPARRKGILVKQPNVEDSPEKTCSISIPTIIVKEPSTSSSGKSSRGSSMEIET--TGPEPPGQLRPDG--SVSNPFAAAIAGAVRDREKRLEARKNSPAFLS------------MDLGDEDP--FIPTPRLR--------QSMSIDEGMFANDKSLEN-IMAPPASLIGSSQLRNEGNLTDFTIPEPMTKPLTTRSRKCPDIG-------SPIGIDDDFQQQVSRKTHDICSPPAPGQSSGNKALKEPVLPPLPPPKGEPHKANLNQPLFIDTKLR---SNIETNFAATTAVGQPKDSGGLF-RHSRESSRQT-----VKVSNPSEQLKNAHNTSQQKSAGLLMVQSLNKAKP-----------QGNSLSDG---FLLEE---SPVMDGEPSDSKLPNSQTTP---------MEEPGKFSSGIPLPLLTSVDIDEEFDVAEPLPPPLEFANSLDIPED------QVAVILKQKKNN-------ETR--AVHHSRASNCMTS-------HAYPP---PPPEMFEPVTDSGIEEAD-------SRNSAGDPHFEANSTIST-----VSSISTLSSEG--IEDACITYANGQIFLLDRPPVPPKPKSKPIIN---KSNAFYRDPLKQESIESIGEPPPLPPPP----LCGVAQTEARKT--LAKHPQELPNPLLPNADPKANVINELSSKLQHMNKDRFP------KQGGSLDPPAVSR------------SIGSREWMAQDTKRIHKVSSSPLPPQASPPAGSGHSSLP----------------------------------------GSAASPTLTDVFSLPSPPMGNAEQCFSISSVS-SQSLSPLTLFQAAADKPFADKPIPLWSKHDVADWLDTLNLA---------EHKKAFLENDIEGSHLPNLQKEDLVDLGVTRVG----------HRMNIEKALKLLMDR---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z9K8-1", "uniprot_id": "A1Z9K8_DROME", "id": "A1Z9K8-1", "name": "", "aln": "-------------------------------------------------------MSGSGAFDDEPPPEPRD--------------------------------GWLLVRIHVPELNVYKCLQFPSERLVWDVKQQVLASLPKELKESFNYGLFAPPANGKAGKFLDEERRLGDYPFNG--PVGYLELKYKRRVYKMLTLDERQLKALHTRANLRRFLECINGGHVEKIAKMCAKGLDPNFHCSESGDTPLTVATGAKKPNKLLIALVNGGALLDYRTKDGSTALHRAVEHDSLEAVSTLLELGASPNYRDGRGITPLYISITRKCEAKITESLLHDHATLGIQDSQGWNEVHQACRHGLVQHLEHLLFYGADMDGRNASGNSPLHVCAVNNQEACARMLLFRGAQRGAQNFANQTPYQVAVIAGNLELAEIIENYKSEDIVPFRGPPRYNPKRRSGIG--------WLSANGAAGAALLAAAGGGFGGAMVGSNGAANGNNGAGGVGLMLSHQNHQQHHAGHHQQQHMHHQHHQNHHQQLQQQQLPHLHTLQLHGPPSPCPSEHMLGAYSSASSSLSEGSSGHRSHEDDISIVTDKSLGDTSDIISDSSGVGTNSDSAACSIGHPSTTVVCMEPYAGNTVGHIRLQPGD-VIEVVGSTDCGLLEGYVRGTNQSGFFPADCVQEVSLRQKHITNVMTASTGMAPQQQQQQHLQQAPAGSSAASYQGSPQLSLGGHSGSSSTLLQQPHQSPSLSVASNGSCQQPLESNEGGASGNGINNRNNNHSVGQYSSATAPRIKKSAYNAPRSVVLHRAKRGFGFILRGAKASSQLMQLRPSERFPALQYLDDVDPGGVADMAGLRPGDFLLTINGEDVTSASHEQVVEMIRSAGALVNLTVVSPQFPHQMQASAQYLPSGARAGSHHLNSGPSTPQSSHRQCATLPRKMTGPGGSGPGSSSGGSVRMAPMPPRRDPKTTLSVGRARAKSMVAGLENGGEKEDDLPHTKSNSVESIATPTPTGIQTGPGTPVQLRTASIKARPTSSRITAAELEELFQRQQGEGSAANASRYATMMTSSRFQSGTDSGAATPPASNGSPMRSGPLVYGSVAEMKRKTARSKHGSGTLRGKPVATPTVGPGGAGGGRDLKRFHSTPDLHGPQLHGSASSIWQASGKGHHSQDDVATLHASLQRLNSNQGELKLGGLGAGSATGAGGAVLPPPNHPPPPPPVGQVVKVETRSSVSEYESTISLQQKLKKRTENDAVTSAAIDGVQSSFNPSANAKIYASPQELRNVMAWKLRQAQEKPSQETSAGSQQPVSQYAAPTQMRPAQQQQQAQQPPTALASHYAAPQVQVQQVQQVQQSPQQSAPQSPPAPPLPQAAPVPAQNGNGNGSTSGAGSAPPIPEPDYSCSESDGEDENSILVARNTKLNEKIALFDVPETSGNSQASGSSSNSGSASISHSLSVEEIQRIRSNLKTSKSSPNGFAKKPEEEKPQQEQQQSHQQPQQLLQPGEDECDNSSSGVSSEQEQLALAAGVTLPGGGKPTDTIKKKPSVTIVEEPKTIPDQPSSNTSHTTKPMAKTTISIGGGGSAVPTATLTVKQLVQQQHAPVIQQQQQQLGSKQPVTAASTNKFTQQSNINSNVMSPQVLGRIPSHHHQQQSSNPNQKLIATQQQILQQQQQQLA-HQQHLQQILKAKAAAAGGASNTAVLVAKHQQKLHKGTSSGHESEMETRSDLEDDDGDLSPSPPAKAFQRHNSLTRKQAAAIAMQRGATRTTAVSLMQLPPPLEADSDGEPSQLTLQRQQSHHPSQTHPHPHQLQQQLQLQQQQQQQQQQQQPMAAHIVGMLPSGQLVAVASGAVAGVPGVGATAVQQGNNNLQQLCTDNLVLAPPPQFCDCNDAKHAPQPHLPTSQYHPQQQQQQQHQQQQQQQQQLQQQLQQQQMLQMHQRLSGGAGAGAVGTLGRVRIVGAMPKANHHRLH", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .: . . . * . : : : *. . : :.: . . :. * ..:. * : . * . ::::. .* *: . * :*:* . . :::.*: *. : ** ::. : : .*:* : . . . * * . . : : : . : . : .:. .:. . ::*. ..: *. :. . . . . .* . *...: .: .. .:: : *.* * : ::* * : :: :: * * * : : : . : : :* *:::*: ::: .... .: .. : .. .. : : : .* : : * : . :. : * .. :: .:: : : . :.:. .* ::* . * : . . *.: . :: .. :: * . . :. * .. : . *. : . . :.. :..: : : :: :: . .*:.::*: ::* .. . * * . .. : *:* : ::: ::... * *..* .:* :: * .* .... : .. . *. : . .. . * .. . .:: :: : . . :: : . * . :*.: : . : .. *:. . . : :. :. :. : . : : :. *. . . . :*.: : * . :* . * : * . . . *..:...: . * :: .* . *:. :*::.. . . * .. . . . *.: :. .. * * * .:: : :.:*** . . :**: : : . . : * : .: **.. .. * : :**.: : * . . .. * : : : . :: .. . . :*. : . *::::. : .*: . : : : : .:. ** .. :. . :. : .::. . : .: .. : . * . . :. * : . : *. :* :::: ::: : . :**::::::: * *:.* *: .: ", "identical_positions": 106, "similar_positions": 449, "identity": "5.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-57", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IZP7-1", "uniprot_id": "H6ST3_HUMAN", "id": "Q8IZP7-1", "name": "Heparan-sulfate 6-O-sulfotransferase 3", "aln": "MDERFNKWLLTPVLTLLFVVIMYQYVSPSCTSSCTNFGEQPRAGEAGPPAVPGPARRAQAPPEEWERRPQLPPPPRGPPEGPRGAAAPEEEDEEPGDPREGEEEEEEDEPDPEAPENGSLPRFVPRFNFSLKDLTRFVDFNIKGRDVIVFLHIQKTGGTTFGRHLVKNIRLEQPCSCKAGQKKCTCHRPGKKETWLFSRFSTGWSCGLHADWTELTNCVPAIMEKKDCPRNHSHTRNFYYITMLRDPVSRYLSEWKHVQRGATWKTSLHMCDGRSPTPDELPTCYPGDDWSGVSLREFMDCTYNLANNRQVRMLADLSLVGCYNLTFMNESERNTILLQSAKNNLKNMAFFGLTEFQRKTQFLFERTFNLKFISPFTQFNITRASNVEINEGARQRIEDLNFLDMQLYEYAKDLFQQRYHHTKQLEHQRDRQKRREERR-LQREHRDHQWPKEDGAAEGTV--------TEDYNSQVVRW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9QYK4-1", "uniprot_id": "H6ST3_MOUSE", "id": "Q9QYK4-1", "name": "Heparan-sulfate 6-O-sulfotransferase 3", "aln": "MDERFNKWLLTPVLTLLFVVIMYQYVSPSCTSSCTNFGEQLRSGEARPPAVPSPARRAQAPLDEWERRPQLPPPPRGPPEGSRGVAAPEDEDEDPGDPEE-EEEEEEEEPDPEAPENGSLPRFVPRFNFTLKDLTRFVDFNIKGRDVIVFLHIQKTGGTTFGRHLVKNIRLEQPCSCKAGQKKCTCHRPGKKETWLFSRFSTGWSCGLHADWTELTNCVPAIMEKKDCPRNHSHTRNFYYITMLRDPVSRYLSEWKHVQRGATWKTSLHMCDGRSPTPDELPTCYPGDDWSGVSLREFMDCSYNLANNRQVRMLADLSLVGCYNLTFMNESERNTILLQSAKNNLKNMAFFGLTEFQRKTQFLFERTFNLKFISPFTQFNITRASNVDINDGARQHIEELNFLDMQLYEYAKDLFQQRYHHTKQLEHQRDRQKRREERR-LQREHRAHRWPKEDRAMEGTV--------TEDYNSQVVRW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1Q9K7-1", "uniprot_id": "F1Q9K7_DANRE", "id": "F1Q9K7-1", "name": "Heparan-sulfate 6-O-sulfotransferase", "aln": "MDDKSNKLLLVPVLTVLFVMIGYQYICPAGSTSCR-FGN----GEG-------------------------FPFSKYPADVKR-----EENEEDAS------------------------FRFQSKFNFTRDDLERHVDFDIKGNDVIVFLHIQKTGGTTFGRHLVRNIHLERPCDCRSGQKKCTCHRPGKAESWLFSRFSTGWTCGLHADWTELTNCVPAVMNKK-LKKDALNRRSFYYITLLRDPVSRYLSEWKHVQRGATWKTALHMCDGRPPTPDELPACYSSEDWTGVTLEEFMACSSNLANNRQTRMLADLSLVGCYNLSSMSEERRAELLLSSAKRNLRRMAFFGLTEFQRKTQFLFERTFGLHFIAAFTQINGTRAAGVTVGTSTRRRIEELNALDMQLYEYARELFLHRIQFCHHQERQEEKKRKRQERRTMKQQKTSAVWQQEDNRAKDTVGKMEVTGVTEDYSSQVVRW", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:: ** **.****:***:* ***:.*: ::** **: **. * .: *.: * *:::*:.. ** .:***: .** *.***:***.*********************:**:**:**.*::************ *:**********:****************:*:** :: : *.*****:***********************:*******.*******:**..:**:**:*.*** *: *******.**************: *.*..* :**.***.**:.*********************.*:**:.***:* ***:.* :. .:*::**:** *********::** :* :. :: *:*.:::::*:*** ::::: * :** :.** ****.******", "identical_positions": 268, "similar_positions": 102, "identity": "55.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-62", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q562C4-1", "uniprot_id": "TMT1B_RAT", "id": "Q562C4-1", "name": "Thiol S-methyltransferase TMT1B", "aln": "------------------------------------------------------------------------------------------------------MDVLVPLLQLLVLLLTLPLHLLALLGCWQPICKTYFP--------------------------------------------------------------------YLMATLTARSYKKMESKKRELFS-QIKDLKGTSNEVTLLELGCGTGANFQFYPPG--CKVTCVDPNPNFEKFLTKSMAENR-HLQYERFIVAYGENMKQLADSS-------------MDVVVCTLVLCSVQSPRKVLQEVQRVLKPGGLLFFWEHVSEPQGSQALLWQRVLEPTWKHIGDGCHLTRETWKDIEKAQFSEVQLEWQPPPFKWLPVG--------PHIMGKAVK----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DD20-1", "uniprot_id": "TMT1B_MOUSE", "id": "Q9DD20-1", "name": "Thiol S-methyltransferase TMT1B", "aln": "------------------------------------------------------------------------------------------------------MDALVLFLQLLVLLLTLPLHLLALLGCWQPICKTYFP--------------------------------------------------------------------YFMAMLTARSYKKMESKKRELFS-QIKDLKGTSGNVALLELGCGTGANFQFYPQG--CKVTCVDPNPNFEKFLTKSMAENR-HLQYERFIVAYGENMKQLADSS-------------MDVVVCTLVLCSVQSPRKVLQEVQRVLRPGGLLFFWEHVAEPQGSRAFLWQRVLEPTWKHIGDGCHLTRETWKDIERAQFSEVQLEWQPPPFRWLPVG--------PHIMGKAVK----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UX53-1", "uniprot_id": "TMT1B_HUMAN", "id": "Q6UX53-1", "name": "Thiol S-methyltransferase TMT1B", "aln": "------------------------------------------------------------------------------------------------------MDILVPLLQLLVLLLTLPLHLMALLGCWQPLCKSYFP--------------------------------------------------------------------YLMAVLTPKSNRKMESKKRELFS-QIKGLTGASGKVALLELGCGTGANFQFYPPG--CRVTCLDPNPHFEKFLTKSMAENR-HLQYERFVVAPGEDMRQLADGS-------------MDVVVCTLVLCSVQSPRKVLQEVRRVLRPGGVLFFWEHVAEPYGSWAFMWQQVFEPTWKHIGDGCCLTRETWKDLENAQFSEIQMERQPPPLKWLPVG--------PHIMGKAVK----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3X9G9-1", "uniprot_id": "G3X9G9_MOUSE", "id": "G3X9G9-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------MTLAVQAMRLVVCIVAFPIFLLNILGMWSWVCKKCFP--------------------------------------------------------------------YFLKRFAMIYNWKMASLKQELFS-NLQEFAGPSGKLTLLEVGCGTGANFKFYPPG--CRVTCIDPNPNFEKFLFKSVAENR-QLQFERFVVAVGEDMHQVTDGS-------------VDVVVCTLVLCSVKNQEKILREVCRVLKPGGAFYFIDHVADERSTWNYFWQQVLARVWFLAFDGCNLTRESWKAIEQANFSKLNLQHIQAPLPLTLVR--------PHIYGYAVK----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A343-1", "uniprot_id": "A0A8I6A343_RAT", "id": "A0A8I6A343-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------MTLAILALRLVVCTLSFPLFLLNLIGVWSWVCKRCFP--------------------------------------------------------------------YFLKRFTVMYNEQMATRKRELFS-NLQEFAGPSGKLSLLEVGCGTGANFKFYPPG--CRVTCIDPNPNFEKFLFKSVAENR-HLQFERFLVAVGEDMHQVADGS-------------VDVVVCTLVLCSVKSQEKILREVCRVLRPGGAFYFMEHVADERSTWNYFWQQVLDPVWFLVFDGCNLTRESWKTLEQASFSKLKLQHIQAPLSWALVR--------PHIYGYAVK----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H8H3-1", "uniprot_id": "TMT1A_HUMAN", "id": "Q9H8H3-1", "name": "Thiol S-methyltransferase TMT1A", "aln": "------------------------------------------------------------------------------------------------------MELTIFILRLAIYILTFPLYLLNFLGLWSWICKKWFP--------------------------------------------------------------------YFLVRFTVIYNEQMASKKRELFS-NLQEFAGPSGKLSLLEVGCGTGANFKFYPPG--CRVTCIDPNPNFEKFLIKSIAENR-HLQFERFVVAAGENMHQVADGS-------------VDVVVCTLVLCSVKNQERILREVCRVLRPGGAFYFMEHVAAECSTWNYFWQQVLDPAWHLLFDGCNLTRESWKALERASFSKLKLQHIQAPLSWELVR--------PHIYGYAVK----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q726-1", "uniprot_id": "A0A8M9Q726_DANRE", "id": "A0A8M9Q726-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------MSRFMDACALSFKVLILPLYIAEHVGLLS-FFKRVFP--------------------------------------------------------------------MIQYKATDWYNNKMNDKKRELFR-NLERFQPPEGSLRILEVGCGSGANFEHYPTG--SKITCTDPNPHFKKYLEKSIEKNE-HLEYDNFIVASGENLQAVEDSS-------------VDAVVCTLVLCSVKDTNKVLQESKRVLRPGGALFFLEHVVSDPSTWAYFFQHVLEPLWYFFGDGCEVTRATWKHIEAAGFSDVKLHHIQAPL-FFMLK--------PHIVGYAVK----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06668-1", "uniprot_id": "OMS1_YEAST", "id": "Q06668-1", "name": "Methyltransferase OMS1, mitochondrial", "aln": "MIVFRRFPTCLLHHIRQPASRSLLLESQRRSLSFTSYKYNSSHIDDDKSKKKLKNVFQMNSNRVIRKQKTKEELAKERFEEQLRSPNRFVRWGAIARSEKFSKGMTKYMIGAYVIFLIYGLFFTKKLFAKDKELERLLKKQEEGNANEYEALRIKELKGKLRRRDELKLEEYKKMQEEGIENFDDIRVQNFDQNKLNEQILPARDTTNFYQEKANEYDKAINMEERVIFLGKRRKWLMKHCQGDVLEVSCGTGRNIKYLDMSRINSITFLDSSENMMEITHKKFREKFPKYKKVAFVVGKAENLVDLAEKGKPSLENEKENQVKYDTIVEAFGLCSHEDPVKALNNFGKLLKPDGRIILLEHGRGQYDFINKILDNRAERRLNTWG--CRWNLDLGEVLDDSDLELVEEKRTHLGTTWCIVAKRKGDVKKKDELGFVEKYLQSSIRKRMESFEKKDDMASKKELEPVPPVSKS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : :.: : . : : : : : :: :* : . . :**:.**:* *::. . :* *.. :: : *.. :: : : *:*. .*:: : : . *.:* :: *** :. : *.: ::*:*.* : : :* . : :. * . : :: : :. :: . : . * . * ", "identical_positions": 26, "similar_positions": 79, "identity": "5.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-64", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q562C4-1", "uniprot_id": "TMT1B_RAT", "id": "Q562C4-1", "name": "Thiol S-methyltransferase TMT1B", "aln": "------------------------------------------------------------------------------------------------------MDVLVPLLQLLVLLLTLPLHLLALLGCWQPICKTYFP--------------------------------------------------------------------YLMATLTARSYKKMESKKRELFS-QIKDLKGTSNEVTLLELGCGTGANFQFYPPG--CKVTCVDPNPNFEKFLTKSMAENR-HLQYERFIVAYGENMKQLADSS-------------MDVVVCTLVLCSVQSPRKVLQEVQRVLKPGGLLFFWEHVSEPQGSQALLWQRVLEPTWKHIGDGCHLTRETWKDIEKAQFSEVQLEWQPPPFKWLPVG--------PHIMGKAVK----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DD20-1", "uniprot_id": "TMT1B_MOUSE", "id": "Q9DD20-1", "name": "Thiol S-methyltransferase TMT1B", "aln": "------------------------------------------------------------------------------------------------------MDALVLFLQLLVLLLTLPLHLLALLGCWQPICKTYFP--------------------------------------------------------------------YFMAMLTARSYKKMESKKRELFS-QIKDLKGTSGNVALLELGCGTGANFQFYPQG--CKVTCVDPNPNFEKFLTKSMAENR-HLQYERFIVAYGENMKQLADSS-------------MDVVVCTLVLCSVQSPRKVLQEVQRVLRPGGLLFFWEHVAEPQGSRAFLWQRVLEPTWKHIGDGCHLTRETWKDIERAQFSEVQLEWQPPPFRWLPVG--------PHIMGKAVK----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6UX53-1", "uniprot_id": "TMT1B_HUMAN", "id": "Q6UX53-1", "name": "Thiol S-methyltransferase TMT1B", "aln": "------------------------------------------------------------------------------------------------------MDILVPLLQLLVLLLTLPLHLMALLGCWQPLCKSYFP--------------------------------------------------------------------YLMAVLTPKSNRKMESKKRELFS-QIKGLTGASGKVALLELGCGTGANFQFYPPG--CRVTCLDPNPHFEKFLTKSMAENR-HLQYERFVVAPGEDMRQLADGS-------------MDVVVCTLVLCSVQSPRKVLQEVRRVLRPGGVLFFWEHVAEPYGSWAFMWQQVFEPTWKHIGDGCCLTRETWKDLENAQFSEIQMERQPPPLKWLPVG--------PHIMGKAVK----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3X9G9-1", "uniprot_id": "G3X9G9_MOUSE", "id": "G3X9G9-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------MTLAVQAMRLVVCIVAFPIFLLNILGMWSWVCKKCFP--------------------------------------------------------------------YFLKRFAMIYNWKMASLKQELFS-NLQEFAGPSGKLTLLEVGCGTGANFKFYPPG--CRVTCIDPNPNFEKFLFKSVAENR-QLQFERFVVAVGEDMHQVTDGS-------------VDVVVCTLVLCSVKNQEKILREVCRVLKPGGAFYFIDHVADERSTWNYFWQQVLARVWFLAFDGCNLTRESWKAIEQANFSKLNLQHIQAPLPLTLVR--------PHIYGYAVK----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6A343-1", "uniprot_id": "A0A8I6A343_RAT", "id": "A0A8I6A343-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------MTLAILALRLVVCTLSFPLFLLNLIGVWSWVCKRCFP--------------------------------------------------------------------YFLKRFTVMYNEQMATRKRELFS-NLQEFAGPSGKLSLLEVGCGTGANFKFYPPG--CRVTCIDPNPNFEKFLFKSVAENR-HLQFERFLVAVGEDMHQVADGS-------------VDVVVCTLVLCSVKSQEKILREVCRVLRPGGAFYFMEHVADERSTWNYFWQQVLDPVWFLVFDGCNLTRESWKTLEQASFSKLKLQHIQAPLSWALVR--------PHIYGYAVK----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9H8H3-1", "uniprot_id": "TMT1A_HUMAN", "id": "Q9H8H3-1", "name": "Thiol S-methyltransferase TMT1A", "aln": "------------------------------------------------------------------------------------------------------MELTIFILRLAIYILTFPLYLLNFLGLWSWICKKWFP--------------------------------------------------------------------YFLVRFTVIYNEQMASKKRELFS-NLQEFAGPSGKLSLLEVGCGTGANFKFYPPG--CRVTCIDPNPNFEKFLIKSIAENR-HLQFERFVVAAGENMHQVADGS-------------VDVVVCTLVLCSVKNQERILREVCRVLRPGGAFYFMEHVAAECSTWNYFWQQVLDPAWHLLFDGCNLTRESWKALERASFSKLKLQHIQAPLSWELVR--------PHIYGYAVK----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F6Y5-1", "uniprot_id": "E7F6Y5_DANRE", "id": "E7F6Y5-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------MSLFLNALAFICKVLTLPLFVGERVGLLS-FYKRLYP--------------------------------------------------------------------RLLSSFTIAYNELMNDKKRELFL-NLERFQPSKGSLRILEVGCGSGANFEHYPTG--SKITCTDPNPHFKTYLEKSMEKNE-HLVYDSFIVASGENLQAVEDSS-------------VDAVVCTLVLCTVKDTNKVLQEAKRVLRPGGAFFFLEHVVSDPSTWAYFFQHVLQPFWYYLQDGCEAIRATWKDIDNAGFSDVKLRHIQAPL-FFMIK--------PHIIGYAVK----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q06668-1", "uniprot_id": "OMS1_YEAST", "id": "Q06668-1", "name": "Methyltransferase OMS1, mitochondrial", "aln": "MIVFRRFPTCLLHHIRQPASRSLLLESQRRSLSFTSYKYNSSHIDDDKSKKKLKNVFQMNSNRVIRKQKTKEELAKERFEEQLRSPNRFVRWGAIARSEKFSKGMTKYMIGAYVIFLIYGLFFTKKLFAKDKELERLLKKQEEGNANEYEALRIKELKGKLRRRDELKLEEYKKMQEEGIENFDDIRVQNFDQNKLNEQILPARDTTNFYQEKANEYDKAINMEERVIFLGKRRKWLMKHCQGDVLEVSCGTGRNIKYLDMSRINSITFLDSSENMMEITHKKFREKFPKYKKVAFVVGKAENLVDLAEKGKPSLENEKENQVKYDTIVEAFGLCSHEDPVKALNNFGKLLKPDGRIILLEHGRGQYDFINKILDNRAER--RLNTWGCRWNLDLGEVLDDSDLELVEEKRTHLGTTWCIVAKRKGDVKKKDELGFVEKYLQSSIRKRMESFEKKDDMASKKELEPVPPVSKS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :.. : . : : : : :: :* : . . :**:.**:* *::. . :* *.. :: *.. :: : *:*. .*:: : : . *.:* :: **: :. : *.: ::*:*.* : : :* . : :. ** : :: : :. :: . : . * . * ", "identical_positions": 26, "similar_positions": 76, "identity": "5.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-66", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZQF7-1", "uniprot_id": "JADE2_MOUSE", "id": "Q6ZQF7-1", "name": "E3 ubiquitin-protein ligase Jade-2", "aln": "--MEEKRRKYSISSDNSDTTDGHVTSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITAMKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRLLPPLKGPPTQMSPDSPTLGEGAHPDWPGGSRYDLDEIDAYWLELLNSELKEMEKPELDELTLERVLEELETLCHQNMAQAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGSWLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKECTGTCIQCSMPSCITAFHVTCAFDRGLEMRTILADNDEVKFKSLCQEHS-------DGGP---RSEPTSEPVEPSQAV----EDLEKVTLRKQRLQQLEENFYELVEPAEVAERLDLAEALVDFIYQYWKLKRRANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVRNLCYMVTRRERTKHTICKLQEQIFHLQMKLIEQDLCREPSGRRSKGKKNDSKRKGREGPKGSSPEKKEKVKAGPESVLGQLGLSTSFPIDGTFFNSWLAQSVQITAEDMAMSEWSLNSGHREDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPSP--LQDGPSARTTPDKQPKKAWAQD---GKGTQGPPMRKPPRRTSSHLPSSPAAGDCPVPATLESPPPLASEILDKTAPMASDLNVQVPGPTVSPKPLGRLRPPREMKVSRKSPGARSDAGTGLPSAVAERPKVSLHFDTEADGYFSDEEMSDSEVEAEDSGVQRASREAGAEEVVRMGVLAS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NQC1-1", "uniprot_id": "JADE2_HUMAN", "id": "Q9NQC1-1", "name": "E3 ubiquitin-protein ligase Jade-2", "aln": "--MEEKRRKYSISSDNSDTTDSHATSTSASRCSKLPSSTKSGWPRQNEKKPSEVFRTDLITAMKIPDSYQLSPDDYYILADPWRQEWEKGVQVPAGAEAIPEPVVRILPPLEGPPAQASPSSTMLGEGSQPDWPGGSRYDLDEIDAYWLELINSELKEMERPELDELTLERVLEELETLCHQNMARAIETQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDKCNVCVHQACYGILKVPTGSWLCRTCALGVQPKCLLCPKRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKISHIPASRWALSCSLCKECTGTCIQCSMPSCVTAFHVTCAFDHGLEMRTILADNDEVKFKSFCQEHS-------DGGP---RNEPTSEPTEPSQAG----EDLEKVTLRKQRLQQLEEDFYELVEPAEVAERLDLAEALVDFIYQYWKLKRKANANQPLLTPKTDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVRNLCYMVTRRERTKHAICKLQEQIFHLQMKLIEQDLCR--------------------------------------------GLSTSFPIDGTFFNSWLAQSVQITAENMAMSEWPLNNGHREDPAPGLLSEELLQDEETLLSFMRDPSLRPGDPARKARGRTRLPAKKKPPPPPPQDGPGSRTTPDKAPKKTWGQDAGSGKGGQGPPTRKPPRRTSSHLPSSPAAGDCPILATPESPPPLAPETPDEAASVAADSDVQVPGPAASPKPLGRLRPPRESKVTRRLPGARPDAGMGPPSAVAERPKVSLHFDTETDGYFSDGEMSDSDVEAEDGGVQRGPREAGAEEVVRMGVLAS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F8E2-1", "uniprot_id": "E7F8E2_DANRE", "id": "E7F8E2-1", "name": "", "aln": "MESEMKRRKYSTSSNDSDTTDSQVTTWSRS--SKN-TGTSSTWVRHEQKRPSEVFRTDFITAMKLPDSAQLSADEFYILCDPWRQEWEKGVQVPANVETIPEPVVRMLPEVSRIPFFSAVQTRSQSEISEP----LSRYDLDDLDVAWLELVNAEFRQLALPELDELTMEQLLVELERRCQQNMQQQIENQEGLGIEYDEDVVCDVCRSPEGEDGNEMVFCDNCNVCVHQACYGILKVPQGNWLCRTCALGVQSKCLLCPRRGGALKPTRSGTKWVHVSCALWIPEVSIGCPEKMEPITKVSHIPASRWALSCSLCCEHSGTCIQCSMPSCTVAFHVTCAFDHGLEMRTTLADNDEVRFKSYCLEHSSVWRSNSSGGVQSDRPDPRHAVPDPAAAQKQEQAEREKASQRKQKLQELEDEFYTLVDPKDIAESLSLPDAHVDFLFQYWKLRRKTNGNKPLVSMKRDEVDNLAQQEQDVLYRRLKLFTHLRQDLERVRNLCCMITRREKIKHSLCNLQEKIFSLQIQLMEQNLVGEKSQRGERKHRNRVQERVKERRK-NSPEKKDKWRSDDNSLFSQLGFSRSFPIDGSLFDSWQAQSIHISAESM-LSRWSLSAGTPETSAS-LLSDQLLRGEESLLSLMMDSSMQN-------TWKTPRLGRKHPKS-----APRSRR-----------------KTLCSPPAKGKVCVTERRCRRGEKTEDFQRSSDGRSDPLQPAIAKMDSCHISEERDSVLE--KRSQKSV-RMHLPRQSKTRCKSQTVESSVQSNTP-------------DTETDGYFSDEEQSDGELRLFSRKSRMPQMHAGKEEVVRRSLLAS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ****** **::*****.:.*: * * ** :.*.* * *:::*:********:*****:*** ***.*::***.***************..*:*******:** :. * : .: .* :.* ******::*. ****:*:*:::: *******:*::* *** *:*** : **.********************************:**************** *.***********.******:***************************************:*************** * :*********** .*********:****** *******:*** * *** .** * :* :*: * : **.: ***:**:**::** **:* ::** *.*.:* ***::*****:*::*.*:**:: * *********************************** *:****: **::*:***:** **::*:**:* *:* ******::*:** ***::*:**.* :*.*.*. * * .*. ***::**:.**:***:* *.*:: :* .:*:* . .* :* * .** : *. : . : * : .* * .. .:. :: : : : * *.: *:: **: *. : ..... . * ***:****** * **.::. . : .** ***** .:***", "identical_positions": 438, "similar_positions": 162, "identity": "51.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-68", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IYM1-1", "uniprot_id": "SEP12_HUMAN", "id": "Q8IYM1-1", "name": "Septin-12", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDPLRRSPSPCLSSQPSSPSTPPCEMLGPVGIEAVLDQLKIKAMKMGFEFNIMVVGQSGLGKSTMVNTLFKSKVWK-SNPPGLGVPTPQTLQLHSLTHVIEEKGVKLKLTVTDTPGFGDQINNDNCWDPILGYINEQYEQYLQEEILITRQRHIPDTRVHCCVYFVPPTGHCLRPLDIEFLQRLCRTVNVVPVIARADSLTMEEREAFRRRIQQNLRTHCIDVYPQMCFDEDINDKILNSKLRDRIPFAVVGADQEHLVNGRCVLGRKTKWGIIEVENMAHCEFPLLRDLLIRSHLQDLKDITHNIHYENYRVIRLNESHLLPRGPGWVNLAPASPGQLTTPRTFKVCRGAHDDSDDEF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FGH0-1", "uniprot_id": "E7FGH0_DANRE", "id": "E7FGH0-1", "name": "", "aln": "MSDISVNDHLEGILSDFEALKRSFDIDDVNEIPAFSPTSSVTSPISPSAILNKTNDVRIPGNQMSPPYRSRINISCSPAQSPVMKNRMVSSLSFNRGTMGKPTINANSGINRAASFQNKFNPNGFISSSGPGSDNDSLHSSSSSLEYQASSKLCSYTSPPQSPVGVGEFKSQRLGSPALKKFSSHGNMFHSEMEGPLVIPTEPIGISHGSMPSLELQMETAGTKRMISPGSRFTNTGPQWSPHNIHNSSTFARDSPLNNQSPKPKDPIRLNKFPLDLDNLVFKSQTESLGAPKPPTSFQMISYSPTVSASPCASISSLDSTDLTIAHNNNNLNEKREPITPPGAIPVPNISESPVPLSPAQTPQFNMVSKPQVVQVAPASPFVSRQMEISNEIDHNDIHAKESVGSILQRIASFSRVETKVPVSDPSPVMPIINGIKKGSPAIHCKELKRLEDTAQEQGLDLEPPVPMEEEKEVMEEMEVEIEDPLPCLSETDTQGIIKGRDLFGYVGIEAVLDQMRRKTMKAGFEFNIMVVGQSGLGKSTLVNTLFKSKVSRKSCTPNYEEKISKTVHLQSVSHIIEEKGVKMKLTVIDTPGFGDQINNENCWEPIVKYVNEQYEKYLKEELNVNRKRRIPDSRVHCCVYFLPATGHWLRPIDVEFMRRLGKIVSIVPVIAKADTLTLEERLEFKQRIRQDLQANGIRVYPQKEYDEDAEDRILNDKIRENIPFAVVGTDKEHQVNGNKVLGRKTKWGIIEVENVAHCEFAHLRDLLIRSHLQDLKDVTHNIHYETYRVKRLNESNAN--------------GLALSPLTLENGTLEKSEAESHL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: ..* ****. :. :::* *********:: *:** ******************:********* : * .*. .:*::*:*::*:*******:**** ***********:***:**: *:*****:**:**: :.*:*:***:********:*.*** ***:*:**::** : *.:*****:**:**:*** *::**:*:*::: * **** :*** :*:***.*:*:.*******:*:** ***. ***************:*****. ***************:*******.*** *****: * :* *:: :.:::..:", "identical_positions": 212, "similar_positions": 82, "identity": "25.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-70", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6RUU0-1", "uniprot_id": "PTX4_MOUSE", "id": "Q6RUU0-1", "name": "Pentraxin-4", "aln": "MR--------------CLKKKTLL--------------FLLIFVSLNVHRTPSQEAHPARQRKPFFERLRRLEEQFQRFQQVTLTHLQNIANNYNVYHNMDVRFQSLVEQSQAVALAMNQSQAAIQGDVAHLKTWYRKSQRRSRKVDARLQALDLSLSTKSRQWVEKEGEQKAQREAIASLALSVQALQDALASLTQQVHS--QGARLAALEGQTQSASSGTVALGLTTAPTPTQLAQ----RGPGSLQLWRDRQVAKSSPQH--------RSSPHDVTVHVQEMQKFQTPSSHQAAP------PR----TYQGP---GNICNTDPVLIFPNTSTENVIFLSPGFLMPLRALSFCSWVRMATSHLGTLLSYATKDNDNKLVLHGRNSLVPGSIHFVIGDPDFRELSLKPLLDGQWHHICIIWTSVEGKYWLHIDRRLVATGSRFREGYEIPPGGSLVLGQEQDTVGGEFDSSEAFVGSISGLAIWDRALLPREVANLASGKELPTGAILTLTNVTSVGGFVQRAKCTCLEQCP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96A99-1", "uniprot_id": "PTX4_HUMAN", "id": "Q96A99-1", "name": "Pentraxin-4", "aln": "MG--------------CSWRKTLS--------------FFLVFVPIYLHGASSQEAAPVGPRKPFFERLRRLEEQFRRFQEVTWTHLQNIASNYNVSYNVDVRFRSLAEESQAVAQAVNRSQASVQGELAQLKAWVRKLQRRGRKVDTRLRALDLTLGERSQQRARERKAHKAQRD----------ALQDSLARLEGLVHS--QGARLAALEGRLPVAHPGTAALGPALVPTPTQPEE----LGPTSLKLQRDRQELRAASEH--------RGPPQDSSAPLQGRREPPASGSHRVLSGTAPKDPRQQAWSPQVP---GEICGVGPTLVFPNASTRNVVFLSPGFVTALRALSFCSWVRTASGRLGTLLSYATEDNDNKLVLHGRDSLLPGSIHFVIGDPAFRELPLQLLLDGQWHHICVIWTSTQGRYWLHVDRRLVATGSRFREGYEIPPGGSLVLGQEQDSVGGGFDSSEAFVGSMSGLAIWDRALVPGEVANLAIGKEFPTGAILTLANAALAGGFVQGANCTCLERCP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TP80-1", "uniprot_id": "A0AB32TP80_DANRE", "id": "A0AB32TP80-1", "name": "", "aln": "MEGRKSPKMLAAEGSFCLLKTLFKGGKVTMTRQVGGSVFLLITVFLLMPMSWTRRGVPADTFKALNNRLRTLNQQFKRFQQMTSTHLQRIGKNHNVTNNVDFKF--LSQQFERISRELRSFREMTEHSLNSLKSWTKSLQKKTNRLHSSLSNMTRALWQNNHHNLREIHKQRAALTDLSHKIQKQQSQIDSLESLKDQVQDGMQDLQTSLKKHQTRIMKLESQIQELLKIISTSKAEDPFNSIRKQHGVLMRHVQTQPKSREHRIRERLLLRSTKQPQTTIRERQWQSTTQPTVQAHEELFQLPLRHKIPHVQSPKEEAKICNVGSMLLFPSTSTENYAIFQKTFQTGIHELSICTWLKVDAKYVGTIFSYATENNDNMLVLYGHNSGKLGLMDFVIGDPTYRELPSQNILDGEWHHLCIIWSSIEGRFWYYLDRHLISNGSKFQKGYEIPPGGFVVLGQEQDSLGGDFDVAEAFVGRLAGFALWTRTLSPVEVSGLADGKGVPQGAVLSLDDVDQMSGSVQHITCECLEHCV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * :. : *:*: * : : : ::.. *. *.: :*** *::**:***::* ****.*..*:** *:*.:* * :: : :: :. : : .: **:* :. *:: .::.: * : :* ..:: .: ::* : *:* * *:. *. : : : : : :.:: : * *. * : :* *.. : :. : : : : :. * * * .:**.... *:**.:**.* ::. * :: **:*:*:: : :**::****::*** ***:*::* * :.****** :***. : :***:***:*:**:* :*::* ::**:*::.**:*::******** :*******::** ** :***** ::*:*:* *:* * **:.** ** .* **:*:* :. .* ** .* ***:* ", "identical_positions": 153, "similar_positions": 157, "identity": "28.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-73", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2KA21-1", "uniprot_id": "A0A0G2KA21_RAT", "id": "A0A0G2KA21-1", "name": "", "aln": "-------------------MKAAYTAYRCLTKDLEGCAMNP----ELTMESLGTLHGPVGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPP-----------------------------------------------------TAHQELGTAAAAAAAAS--RSAMVTSMASILDGS-------DYRPELS----------IPLHHAMSMSCD-------------------------SSPPGMGMSN------------------------------------------------------------------------TYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHHHHHHHHQR-----------------------LSGNVSG--------------SFTLMRDERGLPSMNNLYSPY---KEMPSMS--QSLSPLAATPLGNGLGG--LHNAQQSLPNYGPPG----HDKMLSPN----FDAHHTAMLTRGE-----------------------------------QHLSRG--------------------------------------------LGTPPAA--MMSHLN------------------------------------------------GLH-------------------------------------------HPGHTQSHGPVLAPSRERPPSSSSGSQ-------------VATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAG---------------------------------------------------------------------QVYQSPRKAGPSSQPMNLPSLSTVK----LGYTAKTTPPDQVSEVRIVPK-----------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6XBJ3-1", "uniprot_id": "ONEC2_MOUSE", "id": "Q6XBJ3-1", "name": "One cut domain family member 2", "aln": "-------------------MKAAYTAYRCLTKDLEGCAMNP----ELTMESLGTLHGPVGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPP-----------------------------------------------------TAHQELGTAAAAAAAAS--RSAMVTSMASILDGS-------DYRPELS----------IPLHHAMSMSCD-------------------------SSPPGMGMSN------------------------------------------------------------------------TYTTLTPLQPLPPISTVSDKFHHPHPHHHPHHHHHHHHHHQR-----------------------LSGNVSG--------------SFTLMRDERGLPSMNNLYSPY---KEMPSMS--QSLSPLAATPLGNGLGG--LHNAQQSLPNYGPPG----HDKMLSPN----FDAHHTAMLTRGE-----------------------------------QHLSRG--------------------------------------------LGTPPAA--MMSHLN------------------------------------------------GLH-------------------------------------------HPGHTQSHGPVLAPSRERPPSSSSGSQ-------------VATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC-------------------------------------------------------------------KRKEQEPNKDRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRRSLEKWQDDLGTGGSSSTSSTCTKA-----------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95948-1", "uniprot_id": "ONEC2_HUMAN", "id": "O95948-1", "name": "One cut domain family member 2", "aln": "-------------------MKAAYTAYRCLTKDLEGCAMNP----ELTMESLGTLHGPAGGGSGGGGGGGGGGGGGGPGHEQELLASPSPHHAGRGAAGSLRGPPPPP----------------------------------------------------TAHQELGTAAAAAAAAS--RSAMVTSMASILDGG-------DYRPELS----------IPLHHAMSMSCD-------------------------SSPPGMGMSN------------------------------------------------------------------------TYTTLTPLQPLPPISTVSDKFHHPHPHHHP--HHHHHHHHQR-----------------------LSGNVSG--------------SFTLMRDERGLPAMNNLYSPY---KEMPGMS--QSLSPLAATPLGNGLGG--LHNAQQSLPNYGPPG----HDKMLSPN----FDAHHTAMLTRGE-----------------------------------QHLSRG--------------------------------------------LGTPPAA--MMSHLN------------------------------------------------GLH-------------------------------------------HPGHTQSHGPVLAPSRERPPSSSSGSQ-------------VATSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC-------------------------------------------------------------------KRKEQEPNKDRNNSQKKSRLVFTDLQRRTLFAIFKENKRPSKEMQITISQQLGLELTTVSNFFMNARRRSLEKWQDDLSTGGSSSTSSTCTKA-----------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QUT6-1", "uniprot_id": "A0A8M1QUT6_DANRE", "id": "A0A8M1QUT6-1", "name": "One cut domain family member", "aln": "-------------------MKTAYNAYRCLAKDLDAYAMNP----EMTMD-IGSLH-------------------AGVSHEQDLMSSHSPHHS-RNPGAALR-----------------------------------------------------------IHQDL------SVAPS--RSAMVSSMASILDGGGGGGGGGEYRPELS----------LPLHHAMSMPCD-------------------------TSPP--GMSG------------------------------------------------------------------------TYTTLTPLQPLPPISTVSDKFHHPH--------HHHHHHHQR-----------------------LSGNVSG--------------SFTLMRDERTLPAMNNLYSPYH--KDMSGMG--QSLS-----PLGNGLGS--IHSAQPTLHNYG-------HDKMLSSN----FDAH-TAMLSRGD-----------------------------------QHLSRG--------------------------------------------LGGPAAG--MMPHLN------------------------------------------------GMHA------------------------------------------HPGHPPSHGPVLASNRDRPLSSSSSSCG------------APGSGQLEEINTKEVAQRITAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMWKWLQEPEFQRMSALRLAAC-------------------------------------------------------------------KRKEQDPSKDRSNTPKKSRLVFTDLQRRTLLAIFKENKRPSKEMQMTISQQLGLELSTVSNFFMNARRRSLDKWLDEGSPNNSSS--STCTKA-----------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9NJB5-1", "uniprot_id": "ONEC_DROME", "id": "Q9NJB5-1", "name": "Homeobox protein onecut", "aln": "MDSLNDIIDHQTFSQELVEDASEFITVGHHSERPSQSSQQPNSGQDLTMSMQDIISCPVKHRTCSASGSGSASGSDSVVMVIDALGQGNRQSAYQIVPQQLQQRNMPLPFGLLERDRQHMQHGREVNTSPVDFVSSDINLDGLTVDADVSQTDHSQETAVKQEQKLLIVQSKSQDQSHRRIRMLVDVSSVNSGLG---VHVDDMDEISSDGVGCDDEGVTLSHQHLLEQEEQFGLTSHHPHLQPHTQIIHGLHQRSTHSEMGLDNGHGEVLSVIVHSQDSDKEDCEENDDGDAEGDLENEDDDERDSRSREQLLSHSSYQTLTSVNDRLSSPGFSQTSYATLTPIQPLPPISTMSEKFAYSGHISGGDSGDTDVNGDGAGGGVVEVGEVTNQSSEATGTVSISSGNATSSVCSNNDCSSFSALSMPIGSGHLGLGVLSGVQSPFSSYEKLSSMISPPPNNYLVSCDLHSSVSGRVINSSHLQLSHNGNKKESGTHEHTHRPADVNGGKFSYTGHISRGDSVDNDVNGEKFSFSDHISGGDSGDEDANREKFIYSDHISEGENGPDVNSGTNWLQMHSEREVRLHMPVPAELEARFHISSERRTRLNVPPARGSLSRHLAPNAPICPADWKADDWKHSNAGVVSLTADMPVVVSLTPTPPPLRDDSVSGIKQNERSSPGHREQYFLDKSQEPSSVVADQCSPGINGTPQSVCVIHQQSPSALGNGFQSSSQQAKVSSCASPKGTVSSGGAVSNRIANSSDMEEINTKDLAQRISAELKRYSIPQAIFAQRVLCRSQGTLSDLLRNPKPWSKLKSGRETFRRMYKWLQEPEFQRMSALRMAAAQIPQRAPLSSGMSLGSATGPSGSTGTIPTDLDPHGGPTMIQNPLTNESDSSPASTPVTSVLVGSVVSCRRKEEPQIEQMPQPKKPRLVFTDLQRRTLQAIFKETKRPSKEMQVTIARQLGLEPTTVGNFFMNARRRSMDKWRDDDSKSTMHVAHSRQQQDEQQKDNAHTHSQSQIQDQNHSQNQAIHNSMSQDPYSNLHTTAMSPLGAFDEDADMDLELESHDFDLVDPDEHGDTNDPNGDML", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : :: . : :* ::**. . : . : :.. . : : : *: .*.* : * * *: .::*: .* : *:* :.* * : : :: . *:.. :*:****:********:*:** :. . . : . ***.:. *:.: .. * :..: **: :.:..* . . * ..:.. ::.:: * : * *:: . . *. ::**: :*:*.* *. *.* : ** *:: * . : * : .. ::. **..* . *.::******::****:************************************************:***************:*. : :.* :: :: . :.. *.: :: * : ", "identical_positions": 139, "similar_positions": 138, "identity": "12.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-76", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TAC9-1", "uniprot_id": "SCAM5_HUMAN", "id": "Q8TAC9-1", "name": "Secretory carrier-associated membrane protein 5", "aln": "MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHVSMTKRLYYLWMLNSVTLAVNLVGCLAWLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIPGWGVCGWIATISFFGTNIGSAVVMLIPTVMFTVMAVFSFIALSMVHKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYSNEM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9JKD3-1", "uniprot_id": "SCAM5_MOUSE", "id": "Q9JKD3-1", "name": "Secretory carrier-associated membrane protein 5", "aln": "MAEKVNNFPPLPKFIPLKPCFYQDFEADIPPQHLSLTKRLYYLWMLNSVTLAVNLVGCLAWLIGGGGATNFGLAFLWLILFTPCSYVCWFRPIYKAFKTDSSFSFMAFFFTFMAQLVISIIQAVGIPGWGVCGWIATISFFGTNIGSAVVMLIPTVMFTVVAVFSFIALSMVHKFYRGSGGSFSKAQEEWTTGAWKNPHVQQAAQNAAMGAAQGAMNQPQTQYSATPNYTYSNEM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1R1Z1-1", "uniprot_id": "F1R1Z1_DANRE", "id": "F1R1Z1-1", "name": "Secretory carrier-associated membrane protein", "aln": "MAE--NNFPPLPGFIPLKPCFHQDFE-EIPDQHRTLCKRFYYLWILYGVTLLVNFFGCMAWMFGGGGVTNFGMSMIWVILFTPCSYVCWFRPIYNAFKTDSSFYFMAFFFVFMAQLFIAIIQAIGIPGWGVCGWLGTISFFGTSIFASIIMLIPTLMFTAVSVISFLALTKVHNFYRGSGASMSKAQEEWVSGAWKNPHVQQAAQQAALSAATGAMQNPQSPQYSTP--TYDNTM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** ******* ********:**** :** ** :: **:****:* .*** **:.**:**::****.****::::*:****************:******** ******.*****.*:****:**********:.*******.* ::::*****:***.::*:**:**: **:******.*:*******.:*************:**:.** ***::**: :** **.* *", "identical_positions": 166, "similar_positions": 50, "identity": "70.64%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-77", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9VUX3-1", "uniprot_id": "NOTUM_DROME", "id": "Q9VUX3-1", "name": "Palmitoleoyl-protein carboxylesterase NOTUM", "aln": "MAVEQIDKMAAKAGEATNKWIKPQQPLLTLLLLLATFSQLPAVCSSSILDAASLQEKDPLRDTSMNMIQRNYMVMHSASGSGDHSRSLKRANLANTSITCNDGSHAGFYLRKHPSSKKWIVLLEGGWHCFDVRSCRSRWMRLRHLMTSSQWPETRDVGGILSPHPEENPYWHNANHVLIPYCSSDSWSGTRTEPDTSD-RENSWRFMGALILRQVIAELIPVGLGRVPGGELMLVGSSAGGMGVMLNLDRIRDFLVNEKKLQITVRGVSDSGWFLDREP------YTPAAVASNEAVRQGWKLWQGLLPEECTKSYP-TEPWRCYYGYRLYPTLKTPLFVFQWLFDEAQMRVDNVGAP---VTPQQWNYIHEMGGALRSSLDNVSAVFAPSCIGHGVLFKRDWVNIKIDDISLPSALRCWEHSTRSRRHDKLKRSTEPSTAVSHPEHANNQRHQRHRQRLQRQKHNNVAQSGGQQRKHNHLSKEEREERKRLRQEQRQRRKQRRRQQQQKKANGGQEHRNKKDNSPKSSNGNDQRKQRRRQQLTAEERQEQRKRRRKAQQQQMKMQREQPAAGVFLEASAPQKTRSSNNASAGTKSKKRHRVPRVPEKCGLRLLERCSWPQCNHSCPTLTNPMTGEEMRFLELLTAFGLDIEAVAAALGVDMHTLNNMERTELVNMLTQQAN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E7F0Z8-1", "uniprot_id": "NOTU2_DANRE", "id": "E7F0Z8-1", "name": "Carboxylesterase notum2", "aln": "MNIFCHALFLLLLGVVSCQNNNRNVKPGGKPAKKPNNPAIEATQHGPEADPNSGLAG--AGDSSKETNPGGRGSSQQSASVNKPADDMKLHFLKNTAVTCNDGTAAGFYLKEFKGSKRWLIFLEGGWCCYSKETCDSRYKTIPRLMGSTDWPQTRRGSGLLSAQVDENPHWYNANIVFVPYCSSDVWSGNKAASKPKQGKETEYAFMGSQIIREVIKDLVPKGLKQAK--VVMLAGTSAGGTGVLLNIDKVSSLLE-QQGAEAQVRGLVDSGWFLESKQQKVPDCPDSASCTPADAIKKGLRLWNGVVPEKCKQQYKRGEDWHCFFGHKLYSYISAPLFVVQWLFDEEQLRVENIYMGSQSLSEQQWTYMQNLGKELKNSLKDVTAVFAPSCLSHTLITKSNWTDFQIKGTSLSRALQCWDRS-------------------------------------------------------------------------------------------------------------------------------------------------------FQEANKNSKTALKG--------------------CPFHLIDNCQWPQCNPTCPALIDQATQQEMTLLQVLASMGLDLQKLGLDVRGDISAG----------MVSNGG-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : : * .: : : : .. . : *. .. *. * *:* : . :.::. .. : .:* * **::*****: *****::. .**:*:::***** *:. .:* **: : :** *::**:** .*:**.: :***:*:*** *::****** ***.:: ....: :*..: ***: *:*:** :*:* ** :. :**.*:**** **:**:*:: .:* :: : ***: ******: : .*: :. :*:::* :**:*::**:*.:.* * *:*::*::**. :.:****.****** *:**:*: :: ***.*::::* *:.**.:*:*******:.* :: * :*.:::*.. **. **:**::* * **. .** .. * ::*::.*.***** :**:* : * :** :*::*:::***:: :. : *: : *::: . ", "identical_positions": 177, "similar_positions": 179, "identity": "25.95%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-80", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9WUL6-1", "uniprot_id": "M3K14_MOUSE", "id": "Q9WUL6-1", "name": "Mitogen-activated protein kinase kinase kinase 14", "aln": "MAVMEVACPGTPGSAVGQQKELAKAKEKTQSLGKKQSCIFKLEAVEKSPVFCGKWEILNDVITKGTAKDGSEGGPPAISIIAQAECE--NSQEFSPTFSERIFIAGSQQYSQSESLDQIPNNVAHATEGKMARVCRRGKRHGKARKKRRKKRSKSLAQAGVALAKPLPRTPEQESCTIPVQEDESPLGNLYARNVSQFTKPLGGPGLGHLCFKKQDEGLRPVLPRPELHKLISPLQCLNHVWKLHHPQATGPRPHPTHPFPYSGMPHPFPFYPLEPWKPYMLDSAVLDKLAGVSGQRPLPGPPHLSQLAHGDSQKPLPGPHLESSCPSRGALEKVPVEEYLVHALQGSVSSGQ-AHSLASLAKTWSSGSAKLQRLGPETEDNEGVLLTEKLKPVDYEYREEVHWMTHQPRVGRGSFGEVHRMKDKQTGFQCAVKKVRLEVFRVEELVACAGLSSPRIVPLYGAVREGPWVNIFMELLEGGSLGQLIKQMGCLPEDRALYYLGQALEGLEYLHTRRILHGDVKADNVLLSSDGSRAALCDFGHALCLQPDGLGKSLLTGDYIPGTETHMAPEVVMGKPCDAKVDIWSSCCMMLHMLNGCHPWTQYFRGPLCLKIASEPPPIREIPPSCAPLTAQAIQEGLRKEPVHRASAMELRRKVGKALQEVGGLKSPWKG-EYKEPRPPPQDQATCHQTLPTPPRENPP-------AKANTDGAPEPQPPLPPEPPEPSKAPALNLSKEESGTWEPLPLSSLDPATAKG--PSFPDRRATLPELELQQLEIELFLNSLSQPFSLEEQEQILSCLSIDSLSLSDDSEKNPS-KASQSSRDTLSSGVHSWNSQAEARTCSCSTALARGRPTDIPSYFNGVKVQIQSLNGEHLHIREFHRVKVGDIATGISSQIPATAFSLVTKDGQPVCYDMEVPDSGIDLQCTLAPDGSFA---------WTWRVKHGQLENRP-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q99558-1", "uniprot_id": "M3K14_HUMAN", "id": "Q99558-1", "name": "Mitogen-activated protein kinase kinase kinase 14", "aln": "MAVMEMACPGAPGSAVGQQKELPKAKEKTPPLGKKQSSVYKLEAVEKSPVFCGKWEILNDVITKGTAKEGSEAGPAAISIIAQAECE--NSQEFSPTFSERIFIAGSKQYSQSESLDQIPNNVAHATEGKMARVCWKGKRRSKARKKRKKKSSKSLAHAGVALAKPLPRTPEQESCTIPVQEDESPLGAPYVRNTPQFTKPLKEPGLGQLCFKQLGEGLRPALPRSELHKLISPLQCLNHVWKLHHPQDGGPLPLPTHPFPYSRLPHPFPFHPLQPWKPHPLES-FLGKLACVDSQKPLPDP-HLSKLACVDSPKPLPGPHLEPSCLSRGAHEKFSVEEYLVHALQGSVSSGQ-AHSLTSLAKTWAARGSRSREPSPKTEDNEGVLLTEKLKPVDYEYREEVHWATHQLRLGRGSFGEVHRMEDKQTGFQCAVKKVRLEVFRAEELMACAGLTSPRIVPLYGAVREGPWVNIFMELLEGGSLGQLVKEQGCLPEDRALYYLGQALEGLEYLHSRRILHGDVKADNVLLSSDGSHAALCDFGHAVCLQPDGLGKSLLTGDYIPGTETHMAPEVVLGRSCDAKVDVWSSCCMMLHMLNGCHPWTQFFRGPLCLKIASEPPPVREIPPSCAPLTAQAIQEGLRKEPIHRVSAAELGGKVNRALQQVGGLKSPWRG-EYKEPRHPPPNQANYHQTLHAQPRELSPRAPGPRPAEETTGRAPKLQPPLPPEPPEPNKSPPLTLSKEESGMWEPLPLSSLEPAPARN--PSSPERKATVPEQELQQLEIELFLNSLSQPFSLEEQEQILSCLSIDSLSLSDDSEKNPS-KASQSSRDTLSSGVHSWSSQAEARSSSWNMVLARGRPTDTPSYFNGVKVQIQSLNGEHLHIREFHRVKVGDIATGISSQIPAAAFSLVTKDGQPVRYDMEVPDSGIDLQCTLAPDGSFA---------WSWRVKHGQLENRP-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FEY1-1", "uniprot_id": "E7FEY1_DANRE", "id": "E7FEY1-1", "name": "Mitogen-activated protein kinase kinase kinase 14", "aln": "MQVQRIWNSTVPFSHMAHSDIKAVNRLGSGPDSSTESEGGELEKIVHN---SALWKIIN----HGTAKYEWTHGTEKQSIIAQAECESQDSQEFCP--------NGS--ISSQLVLSSISR-----------------NRPRKKRKRPRRKQGKNVSQANVSVG--VTRVPEQDS----------------------------------------GEGS-----------------SINQVREPVFFSSNSSSTYSTERVSIQETEGPSDSHQWE------------------SQQTSFFSP---SQSYAEESEELKSQLRSEIECS------------LAVTALRDYVTTEEPCFAYGFVKDVLRQKREKDEDEREDSDKNEGILFKEGLQPVNSEYREGREYEQCRF-LKQGSFGEVYSIKDKGTGFICAAKKVPLENFSTEEVGTWSALQSPQVVELFGVVREGPSIVLFMDLKPS-SLGQLVEERGRLPEDLSLHYLQQVLGALHYLHRKRVLHLDIKADNVLLSEDGKDAFLCDFGQSERLDKQGL--SYCQG--LKGTETHMAPEVVLNEYHSSKVDIWSSCCMFLHMLNGCHPWTRYYSRPLCLKIATEPPPLREIPHDCSSHTAEVIKAGLQKDPIKRASAKELSFKTAKALKKVGGLRSQVRGGAYQKPLGKPDSAHSATPTKSNNAMPSHN-------SELQWMSSEQKRNKADGKRNDKTKQKKQTKDTRNDDHSPPKALLHIQHTSPKPQVSKKTEREPTVPEQELRKLEKDFLLSSLSHLPSAELQEQLLSCISSDCLSTRECCDKKDSGRWSVSPGDYDSSGVFSDNSQYDGQTFSRDWLSPTHQP--LSRCFEGVDVYIRDFNGRCIHIRETPRVKVGHIARGISDQISESVFSLQTEDGFLVPHDKEVLENSLLLLCVPAPDVSLCHQYSSDDSGWSWRIREGLLETRDN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * .: . .* * :.:.. . : : . ...:* :** : :. .. *:*:* :**** *. ********* :****.* ** *.. *..*.. :* * **: ::* .*.:::*.*::. :.*.***:* .** .:*:* : . . .. . .*. .. . * : : . * .: .* *: :* : . : * .* * **:. *:: : ..: : .. : . .::.***:*:.* *:**: **** .: : : :******: ::** *** **.*** ** * .**: : :.* **::* *:*.***** : :**:* . *****::: * **** :*:** *.* .*.*** :*:** *:********.**. * *****:: *: :** * * : ***********:.. .:***:******:***********::: *******:****:**** .*:. **:.*: **:*:*::*.** ** *. :**::****:* :* *::* * . . * . :: : : : : : .* . ...:.. * .* :: :..: .. .:*..*:** **::** :::*.***: * * ***:***:* *.** : .:*: * : * *. * ****.* .** :.:: * . . :* . *:**.* *:.:**. :**** *****.** ***.**. :.*** *:** * :* ** :..: * *. *** *:. *:**::.* **.* ", "identical_positions": 313, "similar_positions": 256, "identity": "32.4%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-81", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96HW7-1", "uniprot_id": "INT4_HUMAN", "id": "Q96HW7-1", "name": "Integrator complex subunit 4", "aln": "MAAHLKKRVYEEFTKVVQPQ--EEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRLKIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKHLTDTSHGVRNKCLQLLGNLGSLEKSVTKDAEG--------LAARDVQKIIGDYFSDQDPRVRTAAIKAMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPIPSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAKELYSSGEFSSGRKWGDDAPKEEVDTGAVNLIESGACGAFVHGLEDEMYEVRIAAVEALCMLAQSSPSFAEKCLDFLVDMFNDEIEEVRLQSIHTMRKISNNITLREDQLDTVLAVLEDSSRDIREALHELLCCTNVSTKEGIHLALVELLKNLTKYPTDRDSIWKCLKFLGSRHPTLVLPLVPELLSTHPFFDTAEPDMDDPAYIAVLVLIFNAAKTCPTMPALFSDHTFRHYAYLRDSLSHLVPALRLPGRK-LVSSAVSPSIIPQE--DPSQQFLQQSLERVYSLQHLDPQGAQELLEFTIRDLQRLGELQSELAGVADFSATYLRCQLLLIKALQEKLWNVAAPLYLKQSDLASAAAKQIMEETYKMEFMYSGVENKQVVIIHHMRLQAKALQLIVTARTTRGLDPLFGMCEKFLQEVDFFQRYFIADLPHLQDSFVDKLLDLMPRLMTSKPAEVVKILQTMLRQSAFLHLPLPEQIHKASATIIEPAGESDNPLRFTSGLVVALDVDATLEHVQDPQNTVKVQVLYPDGQAQMIHPKPADFRNPGPGRHRLITQVYLSHTAWTEACQVEVRLLLAYNSSAR---IPKCPWMEGGEMSPQVETSIEGTIPFSKPVKVYIMPKPARR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CIM8-1", "uniprot_id": "INT4_MOUSE", "id": "Q8CIM8-1", "name": "Integrator complex subunit 4", "aln": "MAAHLKKRVYEEFTKVVQQQQ-EEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRLKIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGSKLPENQATQVRLVDVACKHLTDTSHGVRNKCLQLLGNLGSLEKSVTKDTEG--------SAARDVQKIIGDHFSDQDPRVRTAAIKAMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPIPSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAKELYSSGEFSSGRKWGDDAPKEEIDTGAVNLIESGACGAFVHGLEDEMYEVRIAAVEALCMLAQSSPSFAEKCLDFLVDMFNDEIEEVRLQSIHTMRKISNNITLREDQLDTVLAVLEDSSRDIREALHELLCCTNVSTKEGIHLALVELLKNLTKYPTDRDSIWKCLKFLGSRHPTLVLPLVPELLSTHPFFDTAEPDMDDPAYIAVLVLIFNAAKTCPTMPALFSDHTLRHYAYLRDSLSHLVPALRLPGRK-LVSSTVPSNITPHE--DPSQQFLQQSLERVYSVQHLDPQGAQELLEFTIRDLQRLGELQSELAGVADFSATYLQCQLLLIKALQEKLWNVAAPLYLKQSDLASAAAKQIMEETYKMEFMYSGVENKQVVIIQHMRLQAKALQLIVTARTTRGVDPLFGMCEKFLQEVDFFQRCFIADLPHLQDSFVDKLLDLMPRLMASKPVEVIKILQTMLRQSTFLHLPLPEQIHKASATIIEPAGESDNPLRFTSGLVVALDVDATLEHVQDPQNTVKVQVLYPDGQAQMIHPKPADFRNPGPGRHRLLTQVYLSHTAWTEPCQVEVRLLLAYNSGAR---IPKSPWLEGSEMSPQVETSIEGTIPFSKPVKVYIMPKPARR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F2X3-1", "uniprot_id": "E7F2X3_DANRE", "id": "E7F2X3-1", "name": "Integrator complex subunit 4", "aln": "MAAHLKKRVYEEFSKVSQQVTLEEVPSKKLRLTKPSKSAALHIDLCKATNPTDALQYLLSFARKPVEAESVEGVVRILLEHYYKESDNSVRLKIASLLGLLSKTQGFASDCIVDDAINTLNTEKSHQVLAQLLDTLLIIGTQLPDKTAVIQRLIDVACKHLSSTYFGVRNKCLQLLGCLGTVDKPLSKETDTGAGAGAQTSAVRDVLSLISDYFQDQDPRVRTAAIKAMLQLHERGMKIQQTIYNQACKLLSDDYEQVRSAAVQMVWVLSQLYPESIVPIPSSNEEIRLVDDSFGKICHMVSDGSWVVRVQAAKLLGSMHQVSPHFLEQTLDKKLMSDLRRKRTAHERAKELYASGEFSSGRRWADDAPKEKVDTSGVNLIDSGACGAFVHGLEDEMYEVRIAAVEALCSLAQSSRSFAEKCLDFLVDMFNDEIEEVRLQSIHVLRQISTHITLREDQLDTVLAVLEDSSRDIREALHELLCYTNVSTKECIQLALLELLKNLSKYPTDRNSVWKCLKFLGARHPTLVLPIVPELLSTHPYFDTPEPDMDDPAYIAVLVLVFNAAQSCPTMPALFSDHTFRHYAYLRDSLSHLVPHLRLPGRKQTASSGVEASGVGSGSLESAKNFLQDSLVRVSALQNLETPGAQDLLEFTIRDLLRLGELQTELAGSADFCATYLRCQLLLTKALQEKLWTMAVPLCLKQNAKVSTATRQILDETYKLEFLYSGLETQQIATIHNVRLQAKALQLILTARSKRGVDRVLGVCEKFLQDVESFQRLFMTELPHFQDSFVEKLLELMPRLTACKPLDLVKILQTTLRQSRCIHLKLPEQIHRASATIIEPTGESDNPLRFTSGLVVALDIDATLEHVQDPQTTVKVQVLYPDGQSHIIHPKPGDFRTPGPGRVRLITQVYLSHSAWTEPCQIEVRLLLAYSSSSSKLSSSKPAWNESMDGLPTSESSIEGTIHLSKPVKVFIMPKPARR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*************:** * **:.:**********************.*:*******.*************************.* **************** **:.***:***** *:.*************** **::**:: * **:*******:.* .*********** **:::*.::*::: *.*** .:*.*:*.*********************:*::************************::**:***********************:**************************.***.*****************************:********:*.******::**..****:*************************** ***** ***************************.:*:**.:******************************* ******* *:***:******:******:*:********:********:*********:***.***************:****::************:*************** ******* .** * .. :.:::***:** ** ::*:*:. ***:********* ******:**** ***.****:***** ********.:*.** ***. .*:*::**::****:**:***:*.:*:. *:::**********:***:.**:* ::*:******:*: *** *:::***:*****:***:***** :.** :::***** **** :** ******:********:******************:***********.************:::*****.***.***** **:*******:****.**:********.*.: .* .* *. : * *:****** :******:********", "identical_positions": 751, "similar_positions": 153, "identity": "76.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-82", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88758-1", "uniprot_id": "KCNS1_RAT", "id": "O88758-1", "name": "Delayed-rectifier potassium channel regulatory subunit KCNS1", "aln": "-------------------------------MVSEFPGPGSRVPWRPRDEALRVNVGGVRRLLSARALARFPGTRLGRLQAAVSEEQARRLCDDYDAAAREFYFDRHPGFFLGLLHFYRTGHLHVLDELCVFAFGQEADYWGLGENALATCCRARYLERRVTRPR-AWDEDSDAPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGYSLPSKLFSCVSIGVVLASIAAMCIHSLPEYQAREAAAAVAAVAAGRSAEDVRDDPVLRRLEYFCIAWFSFEVSSRLLLAPSTRNFFCHPLNLIDIVSVLPFYLTLLAGAALGDRRGASGEELGDLGKVVQVFRLMRIFRVLKLARHSTGLRSLGATLKHSYREVGILLLYLAVGVSVFSGVAYTAE-EKNVGFDTIPACWWWGTVSMTTVGYGDVVPETVAGKLAASGCILGGILVVALPITIIFNKFSHFYRRQKALEAAVRSSGQREFEDLLSSVDGVSDVS-LETSRETSQEGRSTDLETQAP--SEPAKSHSY------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35173-1", "uniprot_id": "KCNS1_MOUSE", "id": "O35173-1", "name": "Delayed-rectifier potassium channel regulatory subunit KCNS1", "aln": "-------------------------------MVSEFPGPGSRVPWRPRDEALRVNVGGVRRLLSARALARFPGTRLGRLQAAASEEQARRLCDDYDAAAHEFYFDRHPGFFLGLLHFYRTGHLHVLDELCVFAFGQEADYWGLGENALATCCRARYLERRVARPR-AWDEDSDAPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGYSLPSKLFSCVSIGVVLASIAAMCIHSLPEYQAREAAAAVAAVAAGRSAEEVRDDPVLRRLEYFCIAWFSFEVSSRLLLAPSTRNFFCHPLNLIDIVSVLPFYLTLLAGAALGDQRGASGEELGDLGKVVQVFRLMRIFRVLKLARHSTGLRSLGATLKHSYREVGILLLYLAVGVSVFSGVAYTAE-EENEGFHTIPACWWWGTVSMTTVGYGDVVPETVGGKLAASGCILGGILVVALPITIIFNKFSHFYRRQKALEAAVRSSGQREFEDLLSSVDGVSDVS-LETSRDTSQEGRSTDLETQAP--REPAKSHSY------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96KK3-1", "uniprot_id": "KCNS1_HUMAN", "id": "Q96KK3-1", "name": "Delayed-rectifier potassium channel regulatory subunit KCNS1", "aln": "MLMLLVRGTHYENLRSKVVLPTPLGGRSTETFVSEFPGPDTGIRWRRSDEALRVNVGGVRRQLSARALARFPGTRLGRLQAAASEEQARRLCDDYDEAAREFYFDRHPGFFLSLLHFYRTGHLHVLDELCVFAFGQEADYWGLGENALAACCRARYLERRLTQPH-AWDEDSDTPSSVDPCPDEISDVQRELARYGAARCGRLRRRLWLTMENPGYSLPSKLFSCVSISVVLASIAAMCIHSLPEYQAREAAAAVAAVAAGRSPEGVRDDPVLRRLEYFCIAWFSFEVSSRLLLAPSTRNFFCHPLNLIDIVSVLPFYLTLLAGVALGDQ---GGKEFGHLGKVVQVFRLMRIFRVLKLARHSTGLRSLGATLKHSYREVGILLLYLAVGVSVFSGVAYTAEKEEDVGFNTIPACWWWGTVSMTTVGYGDVVPVTVAGKLAASGCILGGILVVALPITIIFNKFSHFYRRQKALEAAVRNSNHQEFEDLLSSIDGVSEAS-LETSRETSQEGQSADLESQAP--SEPPHPQMY------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z6V7-1", "uniprot_id": "A0A8M6Z6V7_DANRE", "id": "A0A8M6Z6V7-1", "name": "Delayed-rectifier potassium channel regulatory subunit KCNS1", "aln": "-------------------------------MVKEK---NAWWILDPKDHLLHINVGGLRNTLCSSILKKFPDTRLGQLLSCDSEDDILQLCDDFDVQRKEFYFDRNPGLFPYVLHFYQTGKLHIMEELCIFSFSQEIEYWGISDFFLDSCCSYRYLDRKLERHHKSWDEESDV-SSVDTSVDEISDLNKDIEHFHEMRFGNIRKCLWLTLENPGYSIPSKLFSLLSICVVLISIATMCINSIPEYQKFDENG------------NLIEDPTMHVLEVFCICWFTFEVVTRMLLAPNHRKFFLLPLNVIDIISVMPIYITIFFDMLIGSE-----SELGNLGKLVQVLRLMRIFRVLKLARHSTGLRSLGATLRHSYREVGILLLYLAVGVSVFSGMAYTAENEEDVGLDTIPACWWWGTVSMTTVGYGDVVPVTVAGKLAASGCILGGTLVVALPITIIFNKFSHFYRKQKALEASVRNNNNKKFVMRQQRNSGDSAIHGHIHCLEDEEMDEDVDFDTGVVNFCYEDHPLTYTVRCVH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.* .: *. *::****:*. *.: * :**.****:* :. **:: :****:* :******:**:* :****:**:**:::***:*:*.** :***:.: * :** ***:*:: : : :***:**. ****.. *****::::: :: * *.:*: ****:******:****** :** *** ***:***:*:**** : . : :**.:: ** ***.**:*** :*:****. *:** ***:***:**:*:*:*:: . :*.. .*:*.***:***:*************************:**********************:***** *:: *:.*********************** **.************ *******************:******:**...:::* . .* * . : .: ....*::: . :. * ", "identical_positions": 271, "similar_positions": 123, "identity": "50.28%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-83", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I5ZYX6-1", "uniprot_id": "A0A8I5ZYX6_RAT", "id": "A0A8I5ZYX6-1", "name": "", "aln": "MGNAAG---------------------------SAEQPAGPTAS----------------------PPKQPAVPKQPMPAAGELEERFTRVLNCMNLPPDKVQLLSQYDNEKKWELICDQERFQVKNPPAAYIQKLKS-YLDTGGVSRKVATDWMSNLGFKRRVQEST--QVLRELETSLRTNHIGWVQEFLNEENRGLDVLLEYLAFAQCSVAYDMEST------------ENVASGTEKNKPLEQSVED------LSK------APPSSVPKSR-LTIKCP-------PSPRLTPAHSRKALRNSRIVS--QKDDVHVCIMCLRAIMNYQSGFSLVMNHPACVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHDIILAAFDNFKEVCGEQHRFEKLMEYFR-NEDSNIDFMVACMQFINIVVHSVENMNFRVFLQYEFTHLGLDLYLERLRLTESDKLQVQIQAYLDNVFDVGTLLEETETKNAVLEHMEELQEQVATLTERLRDTENDSMAKIAELEKQ---LSQARKELETLRERFSESTPMVTSR------------RIPEPEKVPAPTVVR-------PSALELKVEELEEKGLIRILRGPGDVVSIEILPGAAATPSGDDAPAPRVSTDSPSTAESVPEAASPTPPPPPPPPPPLPNLQSQQEALPSAPPLAPPLPGCAAPPPAPPLPGDLPPPPPPPP--LGTDGPVPPPPPPPP---GGPPDILGGQDPEIGPGVKAKKPIQTKFRMPLLNWVALKPSQITGTVFTELNDEKVLQELDMNDFEEQFKTKSQGPSLDIS-------ALKGKTAHKAPTKATLIEANRAKNLAITLRKGNLGADRICEAIETYDLQTLSLDFLELLTRFLPTDYERSLIARFEKEQRPMEELSEEDRFMLRFSRIQRLPERMNTLTFLGNFPDTAQLLMPQLNAIIAASISIKSSDKLRQILEIVLAFGNYMNSSKRGAAYGFRLQSLDALLEMKSTDRKQTLLHYLVKVIAEKYPQLTGFHSDLHFLDKAGSVSLDSVLGDVRSLQRGLELTQREFVRQDD---CLVLKEFLRANSPTMDKLLADSKTAQEAYESVVEYFGENPKTTSPSMFFSLFSRFTKAYKKAEQEVEQWKKEAAA-----DTSGRE---------EPPAPKSPPKARRQQMDLISELKRK----QLKEPLIYESDRDGAIEDIITVLKTVPFT-ARTGKRTSRLLCEAS---LGEEMTL-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JL26-1", "uniprot_id": "FMNL1_MOUSE", "id": "Q9JL26-1", "name": "Formin-like protein 1", "aln": "MGNAAG---------------------------SAEQPAGPTAS----------------------PPKQPAVPKQPMPAAGELEERFTRVLNCMNLPPDKVQLLSQYDNEKKWELICDQERFQVKNPPAAYIQKLKS-YLDTGGVSRKVASDWMSNLGFKRRVQEST--QVLRELETSLRTNHIGWVQEFLNEENRGLDVLLEYLAFAQCSVAYDMEST------------DSVASGAEKSKPLDQSVED------LSK------APPSSVPKSR-LTIK-------------LTPAHSRKALRNSRIVS--QKDDVHVCIMCLRAIMNYQSGFSLVMNHPACVNEIALSLNNKSPRTKALVLELLAAVCLVRGGHDIILAAFDNFKEVCGEQHRFEKLMEYFR-HEDSNIDFMVACMQFINIVVHSVENMNFRVFLQYEFTHLGLDLYLERLRLTESDKLQVQIQAYLDNVFDVGTLLEETETKNAVLEHMEELQEQVATLTERLRDTENDSMAKIAELEKQ---LSQARKELETLRERFSESTPMGTSR------------RIPEPEKVPVPTVVR-------PSALELKVEELEEKGLIRILRGPGDVVSIEILPGAAATPSGDDAQAPRVSTDSPSTAESIPEAASP-PPPPPPPPPPLPNLQSQQEAPPSAPPLAPPLPGCAEPPPAPPLPGDLPPPPPPPP--LGTDGPVPPPPPPPP---GGPPDILGGQGPDIGPGVKAKKPIQTKFRMPLLNWVALKPSQITGTVFTELNDEKVLQELDMNDFEEHFKTKSQGPCLDIS-------ALKGKASQKAPTKTILIEANRAKNLAITLRKGNLGADRICQAIETYDLQTLSLDFLELLTRFLPTDYERSLIARFEKEQRPMEELSEEDRFMLRFSRIQRLPERMNTLTFLGNFPDTAQLLMPQLNAIIAASMSIKSSDKLRQILEIVLAFGNYMNSSKRGAAYGFRLQSLDALLEMKSTDRKQTLLHYLVKVIAEKYPQLTGFHSDLHFLDKAGSVSLDSVLGDVRSLQRGLELTQREFVRQDD---CLVLKEFLRANSPTMDKLLADSKTAQEAYESVVEYFGENPKTTSPSMFFSLFSRFTKAYKKAEQEVEQWKKEAAA-----DTSGRE---------EPPTPKSPPKARRQQMDLISELKRK----QQKEPLIYESDRDGAIEDIITDLRNQPYIRADTGRRSARRRPPGPPLPVTTDLAL-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95466-1", "uniprot_id": "FMNL1_HUMAN", "id": "O95466-1", "name": "Formin-like protein 1", "aln": "MGNAAG---------------------------SAEQPAGPAAP----------------------PPKQPAPPKQPMPAAGELEERFNRALNCMNLPPDKVQLLSQYDNEKKWELICDQERFQVKNPPAAYIQKLKS-YVDTGGVSRKVAADWMSNLGFKRRVQEST--QVLRELETSLRTNHIGWVQEFLNEENRGLDVLLEYLAFAQCSVTYDMEST------------DNGASNSEKNKPLEQSVED------LSK------GPPSSVPKSRHLTIK-------------LTPAHSRKALRNSRIVS--QKDDVHVCIMCLRAIMNYQSGFSLVMNHPACVNEIALSLNNKNPRTKALVLELLAAVCLVRGGHDIILAAFDNFKEVCGEQHRFEKLMEYFR-NEDSNIDFMVACMQFINIVVHSVENMNFRVFLQYEFTHLGLDLYLERLRLTESDKLQVQIQAYLDNIFDVGALLEDTETKNAVLEHMEELQEQVALLTERLRDAENESMAKIAELEKQ---LSQARKELETLRERFSESTAMGPSR------------RPPEPEKAPPAAPTR-------PSALELKVEELEEKGLIRILRGPGDAVSIEILPVAVATPSGGDAPTPGVPTGSPS--PDLAPAAEPAPGAAPPPPPPLPGLPSPQEAPPSAPPQAPPLPGSPEPPPAPPLPGDLPPPPPPPPPPPGTDGPVPPPPPPPPPPPGGPPDALGRRDSELGPGVKAKKPIQTKFRMPLLNWVALKPSQITGTVFTELNDEKVLQELDMSDFEEQFKTKSQGPSLDLS-------ALKSKAAQKAPSKATLIEANRAKNLAITLRKGNLGAERICQAIEAYDLQALGLDFLELLMRFLPTEYERSLITRFEREQRPMEELSEEDRFMLCFSRIPRLPERMTTLTFLGNFPDTAQLLMPQLNAIIAASMSIKSSDKLRQILEIVLAFGNYMNSSKRGAAYGFRLQSLDALLEMKSTDRKQTLLHYLVKVIAEKYPQLTGFHSDLHFLDKAGSVSLDSVLADVRSLQRGLELTQREFVRQDD---CMVLKEFLRANSPTMDKLLADSKTAQEAFESVVEYFGENPKTTSPGLFFSLFSRFIKAYKKAEQEVEQWKKEAAAQEAGADTPGKG---------EPPAPKSPPKARRPQMDLISELKRR----QQKEPLIYESDRDGAIEDIITVIKTVPFT-ARTGKRTSRLLCEAS---LGEEMPL-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B6X1-1", "uniprot_id": "A0ACD6B6X1_DANRE", "id": "A0ACD6B6X1-1", "name": "", "aln": "MGNAAG---------------------------GLEQAEGQEAKGSTGGLNPAPSI----------LKKKCAPPKLPMPPEEELEERFNVVLSTMNLPPDKMKLLSQYDNEKKWELVCDQERFQVKNPPSAYLTKIKSFYQDQGGVTRR----------FKKRVQEST--QVLRELEISLRTNHIGWAQEFLNEENQGLDVLVDYLSYSQSDVPFEVESV------------ENGGSISDNRRMSERSVED------LAKNVNH-SAPHTMTRAARALTVR------------ITSLAHSRKTLRIARLAT--QRDDVHLCIMCLRAIMNYQSGFNLVMTHPRCVNEITLSLNNKNPRTKALVLELLAAVCLVRGGHDIIISAFDNFKDASGEKNRFEKLMEYFM-HDDSNVDFMVACMQFINIVVHSVENMNFRVHLQYQFSQLGLDQYLESLKDMESEKLQVQIQAYLDNVFDVGALLEDAENKGDIVDLVADLQENNAQLTARLQECENGALDKIAELEQQ---LLQATKESALLKESLRESCTQVSTLQQREREREIQREREREQERQSQPSQVDREKGSEKESKLEKKLKELQEKGLLRLERTVSGSLDIDVIPVTLEKIVTQTVTVPDSASQAPP-----SPAAAP---PPPPPPPPLPGAEAPPPPPPPPPPSGS--GGAPPPPPPPPPPGGGPPPPPPPP---GSGPPPPPGAPPAP-------------GAETGP--KARKTIQTKFRMPLLNWQALKPNQVSGTVFSELNDEQVLEALNMDLFAEQFKTKAQGPPADLS-------KLKVKVAEKAPTKVSLLEANKAKNLAITLRKGGMNPDKICTAIESYD-QSLSLDFLELLERFIPSEYEMKLLQNYEKEGRPLEDLSEEDRFISRFGKIPRLSQRINTLTFMGNFPESIKRLQPQLDAIIAASVSLKSSSKLKKMLEIILAFGNYMNSSKRGAAYGFRLQSLDLLLDTKSTDRTQTLLHFIANMVHEKYPELTSFHNELRFVDKAALVSLDGVLQDVRSLERGMEGTKKEFMVQDD---IPALKEFVKANSDVLDSLVKDGKTAQEAYAAVVEYYGENPKTTQPSMFFPIFARFIKAYKQAEQDNEQKKKQEMAAEEQATPSPKK---------KEGTPQKGP--MMPKMDLIAELKKR----QVKP-----QVTDGAIDDIITDLRNSPYR-RGDGRRAAPRQEN-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUC6-1", "uniprot_id": "FRL_DROME", "id": "Q9VUC6-1", "name": "Formin-like protein", "aln": "MGAVKSRTITSADVDADEQLQHPHSHAHHHSMRNGHQHNGSISSGTLQKQDLRYDIGCSSQYQHVRQPSLRSRSQQPMPTTDELDRRFAKVLASMDLPPDKAKLLRNYDDEKKWDMICDQEMVQAKDPPSHYLSKLRT-YLDPKASRSHRLYLFYFLCQKRKMVGESTSTQVLRDLEISLRTNHIEWVKEFLDDTNQGLDALVDYLSFRLQMMRHEQRLQGVLCASEERLNLTNGGDGGEIVMGNSSSVSPGGGGGLLSHGNSTGHGLANGTLDSRQQHTMSYGFLRPTIADALDSPSLKRRSRHIAKLNMGAATDDIHVSIMCLRAIMNNKYGFNMVIQHREAINCIALSLIHKSLRTKALVLELLAAICLVKGGHEIILGSFDNFKDVCQEKRRFQTLMEYFMNFEAFNIDFMVACMQFMNIVVHSVEDMNYRVHLQYEFTALGLDKYLERIRLTESEELKVQISAYLDNVFDVAALMEDSETKTSALERVQELEDQ----LEREIDRNSEFLYKYAELESESLTLKTEREQLAMIRQKLEEELTVMQRML-----------QHNEQELKKRDTLLH---------TKNMELQTLSRSLPRSASSGDGSLANGGLMAGSTSGAASLTLPPPPPPMPASP----TASSAAP----PPPPPPAPPAPPPPPGFSPLGSPSGSLASTAPSPPHAPPMLSSFQPPPPPVA-----------GFMPAP-----------------DGAMTIKRKVPTKYKLPTLNWIALKPNQVRGTIFNELDDEKIFKQIDFNEFEERFKIGIGGALRNGSNGTEVDGSLQSSKRFKRPDNVSLLEHTRLRNIAISRRKLGMPIDDVIAAIHSLDLKKLSLENVELLQKMVPTDAEVKSYKEYIIERKDQQLLTEEDKFMLQLSRVERISSKLAIMNYMGNFVDSVHLISPQVQSIAGASTSLKQSRKFKAVLEIVLAFGNYLNSNKRGPAYGFKLQSLDTLIDTKSTDKRSSLLHYIVATIRAKFPELLNFESELYGTDKAASVALENVVADVQELEKGMDLVRKEAELRVKGAQTHILRDFLNNSEDKLKKIKSDLRHAQEAFKECVEYFGDSSRNADAAAFFALIVRFTRAFKQHDQENEQRLRLEKAAALAASKKENDQVLMRNKVNQKKQQLPSNGALSLQEAVINELKSKAHSVREKKLLQQDEVYNGALEDILLGLKSEPYRRADAVRRSQRRRIDNNRLSRTLEEMDC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** . . . .* * : . : .: ***. **:.** .* *:***** :** :**:****:::**** .*.*:**: *: *::: * * . : :: * *** ****:** ******* *.:***:: *:***.*::**:: : .: . . .. : . **. *:: . . . :* : : .*:: : ::: **:*:.********* : **.:*: * .:* *:*** :*. ************:***:***:**:.:*****:.. *:.**:.***** : *:*********:********:**:**.***:*: **** *** :: **::*:***.*****:***.:*:*::*.* :: : :*::: * : :. : * ****.: * :: ::: : *. . : * * : : ::: *... .. . ::. : * . :.. . :* * .*****. * . * .* .. .. ** .** .. ***** . *.* . . :: : **:::* *** ****.*: **:*.**:**:::: :::. * *:** *. : * *: . * * :. *:* .: :*:**: ** .: : : **.: * : *.*: :*** :::*:: * . .: * : : *:***:*: :.:: *:..:: :.::*** :: : : **:::* .** *:*.* *:: :***:******:**.***.****:***** *:: ****: .:***::. : *:*:* .*..:* ***. *:*:.*: **:.*::*:: .::* : . *::*:. .. :..: * : ****: ***:*:..:.:... **.:: ** :*:*: :*: ** : * . : : :* *** : : * . :**::**: ::. *: :*: ", "identical_positions": 353, "similar_positions": 337, "identity": "28.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-84", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A5I4-1", "uniprot_id": "D4A5I4_RAT", "id": "D4A5I4-1", "name": "Neuron navigator 1", "aln": "MNGMANVNSASRPHYASSIPVPRASSQTRIHTPGASPQLRPRQQADLALSPQRGVSPRRGKAAVSSRNSSPKAYRGRGTPRGAGPARELAGSVESLPGSPWNSPRVTPKTGSRRTGETQSTQKKKTQEGIPVRQTRGRSPPQTSCHGETQIPGPPEGRLPSGCRGKDQRNINYKAPRCLEPEEGEASGTSSPVLSPVQSARPSATPGVISFSSAHQQSQPITATVAPFQYRLQTDQEPGPVPQESRVLDGYTSPPIRTEDSFSCVDARIVHALLTGRMLGSSVKSVQPEVELSGGSGSGGDEGADEPRGASRKAAAADGRGMLPKRAKAAGSSGSMAKASAAELKVFKSGSVDSRVPGGLPVSNLRKQKSLTNLSFLTDSEKKLQLYEPEWSDDMAKAPKGLGKLGPKGRETPLMSKTLSKSEHSLFQPKGGPAGGAKTPLAPLAPSLGKPSRIPRGPYAEVKPLSKAPEAAVSDDGKSDDELLSSKAKAQKGSGTVPSAKGQEERAFLKVDPELVVTVLGDLEQLLFSQMLDPESQRKRTVQNVLDLRQNLEETMSSLRGSQVTHSSLEMS-CYDSDDANPR----SVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGSCRSEGPPAWYMHGERAHYSHTMPMRSPSKLSHISRLELVESLDSDEVDLKSGYMSDSDLMGKTMTEDDD---ITTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPTTPTASRRSSTIVLRTDSEKRSLAESGLSWFSE-SEEKTPKKLEYDSGSLKMEPGTSKWRRERPES-----CDDSSKGGELKKPISLGHPGSLKKGKT-------PPVAVTSPITHTAQSALKVAG-KPEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTG--------GSATLSKIQKSSGIPVKPLNG---RKTSLDVSNSVEPGFLAPGARSNIQYRSLPRPAKSSSMSVTG-------RGGPRPVSSSIDPSLLSTK----QGGLTPSRLKE--PSKVASGRSTPAPVNQTDREKEKAKAKAVA---LDSDNISLKSIGSPESTPKNQ-ASHPPATKLAELPP---TPLRATAKSFVKPPSIANLDKVNSNSLDLPSSSD--THASKVPDLHATSSSTGSPLPS--CFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSTAPIPTP---PTAPSEEETEELPWSGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKERRHSHTIGGLPESDDQAELPSPPALSMSLSAKGQLTNIVS--PTAATTPRITR----------SNSIPTHEAAFELYSGSQMGSTLSLAERPKGMIRSG-------------SFRDPTDDVHGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKK----------------NSEAQAVIQGALN------------ASEATPK----------ELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWVYELRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSNSSSVGTEVTETPAHSAPHTRLFQANEEEEPEKKEVSELRSELWEKEMKLTDIRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAP-------------------GPSSGSTPGQAPGSSALSSPRRSLGLALSHPFSPSLTDTDLSPMDGISTCGPKEEVTLRVVVRMPPQHIIKG--------------------------------------------------DLKQQE----------------------------FFLGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSLSHVKRVLDAEPPEMPPCR---RGVNNISVALKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLVLSGPSGTGKTYLTNRLAEYLVERSGREVTDGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGIGDVPLVILLDDLSEAGSISELVNGALTCK-YHKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNVEPANGFLVRYLRRKLVESDSDVNANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKA-AWEDPVEWVRDTLPWPSAQQDQSKLYHLPPPSVGPHSIASPPEDRTVKDSTPNSLDSDPLMAMLLKLQEAANYIESPDRET---ILDPNLQATL-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CH77-1", "uniprot_id": "NAV1_MOUSE", "id": "Q8CH77-1", "name": "Neuron navigator 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLGSSVKSVQPEVELSGGSGSGGDEGADESRGASRKAAAADGRGMLPKRAKAAGGSGSMAKASAAELKVFKSGSVDSRVPGGLPTSNLRKQKSLTNLSFLTDSEKKLQLYEPEWSDDMAKAPKGLGKLGPKGRETPLMSKTLSKSEHSLFQPKGGSTGGAKTPLAPLAPSLGKPSRIPRGPYAEVKPLSKAPEAAVSDDGKSDDELLSSKAKAQKGSGTVPSAKGQEERAFLKVDPELVVTVLGDLEQLLFSQMLDPESQRKRTVQNVLDLRQNLEETMSSLRGSQVTHSSLEMP-CYDSDDANPR----SVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGSCRSEGPPAWYMHGERAHYSHTMPMRSPSKLSHISRLELVESLDSDEVDLKSGYMSDSDLMGKTMTEDDD---ITTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPTTPTASRRSSTIVLRTDSEKRSLAESGLNWFSE-SEEKTPKKLEYDSGSLKMEPGTSKWRRERPES-----CDDASKGGELKKPISLGHPGSLKKGKT-------PPVAVTSPITHTAQSALKVAG-KPEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTG--------SSATLSKIQKSSGIPVKPVNG---RKTSLDVSNSVEPGFLAPGARSNIQYRSLPRPAKSSSMSVTG-------RGGPRPVSSSIDPSLLSTK----QGGLTPSRLKE--PSKVASGRSTPAPVNQTDREKEKAKAKAVA---LDSDNISLKSIGSPESTPKNQ-ASHPPATKLAELPP---TPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSD--THASKVPDLHAPSSSTGGPLPS--CFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSAPIPTP---PTAPSEEDTEELPWSGSPRAGQLDSSQRDRNTLPKKGLRYQLQSQEETKERRHSHTAGGLPESDDQAELPSPPALSMSLSAKGQLTNIVS--PTAATTPRITR----------SNSIPTHEAAFELYSGSQMGSTLSLAERPKGMIRSG-------------SFRDPTDDVHGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKK----------------NSEAQAVIQGALN------------ASEATPK----------ELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWVYELRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSTSSSVGTEVTETPAHSVPHTRLFQANEEEEPEKKEVSELRSELWEKEMKLTDIRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAP-------------------GPSSGCTPGQVPGSSALSSPRRSLGLALSHPFSPSLTDTDLSPMDGISTCGSKEEVTLRVVVRMPPQHIIKG--------------------------------------------------DLKQQE----------------------------FFLGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSLSHVKRVLDAEPPEMPPCR---RGVNNISVALKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLVLSGPSGTGKTYLTNRLAEYLVERSGREVTDGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGIGDVPLVILLDDLSEAGSISELVNGALTCK-YHKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNVEPANGFLVRYLRRKLVESDSDVNANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKA-AWEDPVEWVRDTLPWPSAQQDQSKLYHLPPPSVGPHSTASPPEDRTVKDSTPNSLDSDPLMAMLLKLQEAANYIESPDRET---ILDPNLQATL-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NEY1-1", "uniprot_id": "NAV1_HUMAN", "id": "Q8NEY1-1", "name": "Neuron navigator 1", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLGSSVKSVQPEVELSSG---GGDEGADEPRGAGRKAAAADGRGMLPKRAKAPGGGGGMAKASAAELKVFKSGSVDSRVPGGPPASNLRKQKSLTNLSFLTDSEKKLQLYEPEWSDDMAKAPKGLGKVGSKGREAPLMSKTLSKSEHSLFQAKGSPAGGAKTPLAPLAPNLGKPSRIPRGPYAEVKPLSKAPEAAVSEDGKSDDELLSSKAKAQKSSGPVPSAKGQEERAFLKVDPELVVTVLGDLEQLLFSQMLDPESQRKRTVQNVLDLRQNLEETMSSLRGSQVTHSSLEMT-CYDSDDANPR----SVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGSCRSEGTPAWYMHGERAHYSHTMPMRSPSKLSHISRLELVESLDSDEVDLKSGYMSDSDLMGKTMTEDDD---ITTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSE-SEEKAPKKLEYDSGSLKMEPGTSKWRRERPES-----CDDSSKGGELKKPISLGHPGSLKKGKT-------PPVAVTSPITHTAQSALKVAG-KPEGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPSTSGSFGYKKPPPATGTATVMQTG--------GSATLSKIQKSSGIPVKPVNG---RKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGG------RGGPRPVSSSIDPSLLSTK----QGGLTPSRLKE--PTKVASGRTTPAPVNQTDREKEKAKAKAVA---LDSDNISLKSIGSPESTPKNQ-ASHPTATKLAELPP---TPLRATAKSFVKPPSLANLDKVNSNSLDLPSSSDT-THASKVPDLHATSSASGGPLPS--CFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEELTWSGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEETKERRHSHTIGGLPESDDQSELPSPPALPMSLSAKGQLTNIVS--PTAATTPRITR----------SNSIPTHEAAFELYSGSQMGSTLSLAERPKGMIRSG-------------SFRDPTDDVHGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKK----------------NSEAQAVIQGALN------------ASETTPK----------ELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWVYELRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSTSSSVGTDVTEGPAHPAPHTRLFHANEEEEPEKKEVSELRSELWEKEMKLTDIRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAP-------------------GPSSGSTPGQVPGSSALSSPRRSLGLALTHSFGPSLADTDLSPMDGISTCGPKEEVTLRVVVRMPPQHIIKG--------------------------------------------------DLKQQE----------------------------FFLGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSISHVKRVLDAEPPEMPPCR---RGVNNISVSLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLVLSGPSGTGKTYLTNRLAEYLVERSGREVTEGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGIGDVPLVILLDDLSEAGSISELVNGALTCK-YHKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNVEPANGFLVRYLRRKLVESDSDINANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKA-AWEDPVEWVRDTLPWPSAQQDQSKLYHLPPPTVGPHSIASPPEDRTVKDSTPSSLDSDPLMAMLLKLQEAANYIESPDRET---ILDPNLQATL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JWC7-1", "uniprot_id": "A0AC58JWC7_DANRE", "id": "A0AC58JWC7-1", "name": "Neuron navigator 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSHQTDLLVVIFWTMTMSQSSSGIPLPRSFSKGDSRSFSAAFLTPAGQNKSGRSSSTSS-------VSSLSVSKEFLKGTSLRGPRAQFIPAATNSSPNVPKREVIPQ--------KSPQGLRRGSLPQDGFRDMEKHTNRNWRTGHQHFRSLDNESESESGQRRPSNGN-MLWETSAAVQRDAQKQRTKRMAYPDGETKSLARNTGRESPRMAAVPPIRFRLQVREDVEASLEDLSGYTSDWMEVCW-EDLDPESQRKRTVQNVLDLRQNLEETMSSLRGTQLSQSCLESSVCYDSDETNAR----SISSLSNRSSPLSWRHGQSSPRLQAGDAPSSTGSSYLSGTKASQYT------SQTMPARCSSRLSHTSRSEFLDAGDSD---LKSGYLSDSDVLCKSLNDEDDDDNLANGWDESSSISSGLSDGSDNLSSEDLNASSSLNSLPTTPVGSRRNSSVMLRTDAEKRSLVESGLAWYSEDSKCLRKTDGVYDTGSLKSEP-SCKWRKTRLPDGP---AMDKMNKGELKKPQSLGQTSSFRKSRN-------PPVGVTSPITHTSQSVLKVAVCKGDPKAVDKVKMSVKATGLQRSRSDAGRD--NEHRKPPSGLMKPSAGSSFGYKKP-LTTGTATVLTPGGAT--ITSGSATVGKTPKSSGIPIKPVPGGGARKNSLDAS-GSEQGFLAPNARGSIQYRSLPRPAKNSAMSLTG-----------RPISGNIDSSLLSLKPVPALPNTMPSRGKDGGSLKAASRTSSTGPVNQTDREKEKERAKAKADLEISCLKAESQADGCGETLEKIHRVRRTSSSKYPELSSPTSTPRLLSSKSLAHPPSLAHLDKLNSNSLDSCIPIH--DLPPKIPPFSKLQDLAGGRVAP--RLSPSPAPVLHIDSPSCFSG----QALSVSSSPILYPKMSGLHRSMESLPLHMSLPAKADLGE------------REEGRSTGTWGASSRT---SVTLGDRYSSG--------HSEGEGRERRHSHTITSMTDSATPPQLPSPTHTTPAYIGKTPPTSVVTPIPNSGSGSGITR----------SSSIPASDLGYDLYGTSPLGSSLSLADRPKSMMRSG-------------SFREPAEDVHGSVLSLASNASSNYS---------QIRILRRELESSQDKVANLTTQLAANANLVAAFEQSLALMTARLQSLSVTSEQKDTELQDLKETIEVLKTK----------------NTEAQTLIHGALS------------TPDPMPKEGRAFTACASELQIDRQNSSESISSLNSITSHSSAGSLKEQEAKKKKKKSW---LRSSFNKAFS-KKGPK--APYADIEEIATPEASAPSSPKIHHNVDNTFTKASTSTLGSCGGPEETER-------------------DEKVVSELRSELWEKERKLTDIRLEALSSAHQLEQLQEAMTNMQLTVENLKAENDQLKTGGPT----------------SRPPSSTSQSSGLGSLGVSSPRQSVS-SFSKTAGTGQTEPYPDVFHSPTSTLQKDESLVRVLVRIPNQQLFKD--------------------------------------------------EVKQLE----------------------------FFIGSVRISGRTDWFSLDSAVIQAFKEYLSVVDPGSSLGLSQDSIYSYSLSHLKRVLGAQPPETPPVRLYSRGQACITVALKGLKEKCVDVLVFETLVPKPMMQHYISLLLKHRRLILSGPSGTGKTYLTYRLAEYLVERSARELTPAITNTFNMHRQSCKDLQLYLANLANQIDRESSTAEIPLVVILDDVHEPTSLSELVNGALTCK-YHKCPYIIGTTNQPVKMSPNHGLHLSFRMVTFSNNVEPANGFLVRYLHRKLMEAEDPRSVTNEDLLRVLDWVPRLWYHLHTFLEKHSTSDFLIGPCFFLSCPVTVEDFRTWFIDLWNHSIIPYLQEGSKDGIKVHGQKS-VWEDPVEWVRGSLPWPSAQQDQAKLFHLPPPSTGPGSPSQPADERTHKETPPSSVESDPLMAMLLKLQEAANHIESPEKE-----TDPKLPPL------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIQ9-1", "uniprot_id": "NAV_DROME", "id": "Q9VIQ9-1", "name": "Protein neuron navigator", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------MLARCVSYQGSCDNINGILTRDYAEIYTDWANYYLERAKSKRKVTDLSADCRDGLLLAEVIEAVTSFKVPDLVKKPKNQQQMFDNVNSCLHVLRSQSVGGLENITTNDICAGRLKAVLALFFALSRFKQQAKQTKSIGVGCGGGVGGSSSTLTGSGSVLGIGIGGLRTPGSSLNQDKNQQEQQQQQQQQQTPQQLAQSLENGNEMVNRQIAPAYAKVNGGTAIPLPATVMVQR------RCPPDKVRPLPPTPNHTPSIPGLGKSGSDFNTSRPNSPPTSNHTIQSLKSGNNNSLRPP--SIKSGIPSPSSPQTAPQKHSMLDKLKLFNKEKQQNAVNAASVASKTQIQSKRTSSSSGFSSARSERSDSSLSLNDGHGSQLKPPSISVSSQKPQPKTKQSKLLAAQQKKEQANKATKLDKKEKSPARSLNKEESGNESRSSTMGRTGKSSLVRAVGGVEKNTPKTSSKSSLHSKSDSKSSLKAPQLLQSPSSGGLPKPIAAIKGTSKLPSLGGGAGHLPAAESQQNQQLLKRETSDISSNISQPPPAEPPISTHAHIHQNQTPPPPYYANSQPTSHISSHG--FLSEPSTPQHSSGIYGSSRLPPPKSALSAPRKLEYNAGPHILSSPTHHQRQGLPRPLVNSAPNTPTASPNKFHTIPSKIVGTIYESKEEQLLPAPPPASGGSSILPMRPLLRGYNSHVTLPTRGARGGHHPHQSYLDFCESDIGQGYCSDGDALRVGSS-PGGSRFHDIDNGYLSEGSSGLNGPSSSAGGISPGKHFLSMMRARTQLPTTIEERIRNSRGSLDSIGTAANGSSAASQASSSGGSTTTHAQNNNNNNNNNSGGGAKMDGSPHHRPGSRNGRDNWSKMPEPLNGQKVEKSDKSSPSRRSMGGGGSGSSSKQGSPSSSSRTKGVPP-SFGYVKRANGSIASTAEQQNIAMMMAAGGAGANGLPCGRTAHVSAVPRTASGRKVAGGTQTLPNDMNKLPPNTQHRSFSLTGPTATQLSQSIRERLATGSHSLPKPGSDLHVFQHRISNRGGTRHDGSLSDTQTYAEVKPEYSSYAMWLKHSNTAGSRLSDGESVEQLQIGSPALTRHGHKMIHNRSGGPGQMAGQMSGNESPYVQSPRMNRSNSIRSTKSEKMYPSMMSRAGEVEIEPYYCLPVGTNGVLTAQMAAAMAAQSQAAQGNPGVGVNVGGVAWSQPTSPTPLTRGPFNTAAGASVLSPTHGTTSAAGLVGPGGGAGGGAMVGHRLTYPKKNDEVHGSAASLLSGGSSLYGNAEER-QAHEIRRLKRELQDARDQVLSLSSQLSTNAHVVTAFEQSLSNMTNRLHQLTATAERKDGELTDMRQTIELLRKQSIQAGLTTAHMQSMGVQTQGQGQVQGQALGQALGQPGSDQKPPNSGSQRAINANNGSMPLGMQRQHSTDSMCSLNSISSGCSAAQ--DKNKANKKKGWLRSSFTKAFSRNAKISKTSRHVGHHHHHNHSQQELASGKLPLHNGHGEPLGLASLATQPAPPLPNSKQSSPAKTVTLIDNAKPIDAIDQEDQHVVEDLKKQLREKDLVLTDIRLEALSSASQLESLKEMMNKMRAEMMSLKHNNERLQKLVTTRSLAGSEASLGQAISPNGSVAGSSEVSRRYSLADSNSRPPMELPARLSEELELEEDCLPPAPAPEQPPPPAPNGVSVAPLSPSTHVDLTPPPPALEAAPMASPVHMASATEELADVCDGKKIAIACYLGQPEAFAKYCEELQELDGFYANGHEADSQSQSERKSNYTSASCNEFVIACTYISGKTTWQNLDYVVRKTFKDYVARIDPGTNLGLNTDSITSYHLGEAKRGPEMGFPELLPCGYIVGSVRTLYICLQG-----VGSLAFDSLIPRSIVHRYISLLTEHRRLILCGPSGTGKSYLARRLAEFLVARSARGNPSEAIATFNVDHKSSKDLRQYLGHIAEQAAIANGVSELPSVIILDNLHHASALGDVFSCLLSAGPANKLPCIIGTMSQATCNTTNLQLHHNFRWVLTANHMEPVKGFLGRFLRRRLFQLELQTQHPQPELAAVLAWLPSVWQHINRFLEVHSSSDVTIGPRLFLACPMDLKDSQVWFTDIWNYHLSPYLVEAVREGVQLYGRRGGAWNDPSAFIRNSYPWPYGPDSVPPLRQINAEDVGLEGVALTNGD-----------QQDPLLNMLMRLQEAANYSEAQDQESDCASLDSNVTPESSAGAE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . .. * . . . . . * .. . . . .. .: . . * . : : . . : :.* . : .:. . :: .. .: . . . . .: .. .. . : . . : : . . . .: : . ** * . .* . : : : . *.* .:* .:. : . *..: .. . .* .: *. * *:** .*.. . . ... : : .* . : : . :*::. :: : . : ::.. .:... .. :* :. ..: .. ** *:: .*: : : .:: * .. . * . *::*. .. : : *: : :. . .:: :.: **.. *.* . : : : *: . ** *:. .: * *. . .. .: : *:: : .. .. :. : :* . : *** * *.. .. : .:. :.. . .. : ... : * . .: .. . : : ... .: . ... ::*. . :. : : .. : . .: *. : .:: . :.: .: . . . . * .. :.. *.*.. *:: . . *:.. . * : : .. . .. . :. . :* . :..: : . . . . . . . : :.: : . : :.. * :: . : : *. : . .:: .* :: . ::****. ** *..** *. :** *:***:.::::* .*::**::**::*:****** ** **: *: *:*.** ** *:::**:.*:.: :::.* ::* ..:. .: * :.**:*::*:.*****:* .* .. : : :*** : .:*.: . .* .: . : . :. :*. . : *. : ... . ... :. ::: *.:*:.:* **: *********.** **:.*:* * :*: : ** :*::*: . :. : . * . *..* .: . . : . : * * :: :::: : *.:.. :**:. * ** .* :.**:*:: :**.:.***. :** .* :.. ** ** * . : :.*:* *. *.*::*:*:.::::***** :****:*.*******:**: ****:** **.* . ***:.::*.***: **.::*:* .. .::* *::**:: .. ::.::.. *:. :* * **** .*.. :.* ** .** : :*::**.:*** *:*:*:*.: : . : :* ** *:* :* *:: *** **:**. *** :**:**: ::* :.** *:** : *** *. ::*::::*::. .*:** ::*.: *** . :. . * :: . .* . : . : :.***: **::******: *: ::* *.:: . ", "identical_positions": 310, "similar_positions": 612, "identity": "13.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-85", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99P74-1", "uniprot_id": "RB27B_RAT", "id": "Q99P74-1", "name": "Ras-related protein Rab-27B", "aln": "----------------------------MTDGDYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVYDTQGADGSSGKAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLLDQREVNERQARELAEKYGIPYFETSAATGQNVEKSVETLLDLIMKRMEKCVEK-------TQ---VPDTVNGVNSGKVDGEKPAEKKCAC------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99P58-1", "uniprot_id": "RB27B_MOUSE", "id": "Q99P58-1", "name": "Ras-related protein Rab-27B", "aln": "----------------------------MTDGDYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVYDTQGADGASGKAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLPDQREVNERQARELAEKYGIPYFETSAATGQNVEKSVETLLDLIMKRMEKCVEK-------TQ---VPDTVNGGNSGKLDGEKPAEKKCAC------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O00194-1", "uniprot_id": "RB27B_HUMAN", "id": "O00194-1", "name": "Ras-related protein Rab-27B", "aln": "----------------------------MTDGDYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVYNAQGPNGSSGKAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLIGNKADLPDQREVNERQARELADKYGIPYFETSAATGQNVEKAVETLLDLIMKRMEQCVEK-------TQ---IPDTVNGGNSGNLDGEKPPEKKCIC------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T9E2-1", "uniprot_id": "A0AB32T9E2_DANRE", "id": "A0AB32T9E2-1", "name": "small monomeric GTPase", "aln": "MRTGVVFYGLTHIRNKSKNTPGFSSSSTMTDGDYDYLIKLLALGDSGVGKTTFLYRYTDNKFNPKFITTVGIDFREKRVVYTTNSPNGTTGKTFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQSFLNVRNWMSQLQANAYCENPDIVLVGNKADLADQREVQEKQAKELADKYGIPYFETSAATGSEVDKAVVTLLDLVMKRMEQCVEK-------PS---ADANTSDGSS-KLSAAPAQQKKCAC------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O76901-1", "uniprot_id": "O76901_DROME", "id": "O76901-1", "name": "", "aln": "-----------------MRAAPPEPEPLQLAGSGE---QFLVLGDSGVGKTCLLYQYTDGRFHTQFISTVGIDFREKRLLYNSR------GRRHRIHLQIWDTAGQERFRSLTTAFYRDAMGFLLIFDLTSEKSFLETANWLSQLRTHAYSEDPDVVLCGNKCDLLQLRVVSRDQVAALCRRYRLPYIETSACTGANVKEAVELLVGRVMERIENAACNREFSLLLTQSRCLPNIAYGQPEDLVRLHDRREEPCSRRNCRNC", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. : ::*.********* :**:***.:*:.:**:**********::* :. *: .::***:****************:********:*****::***:. **:***:::**.*:**:** ***.** : * *.. *. *. :* :**:****.** :*.::* *:. :*:*:*:.. : .. . . . : :: * ", "identical_positions": 103, "similar_positions": 66, "identity": "39.31%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-90", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZGQ8-1", "uniprot_id": "D3ZGQ8_RAT", "id": "D3ZGQ8-1", "name": "", "aln": "------------------MATVAAAAAAAVAAMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDIGHGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKYLCECQFDDNLKFKNIINEEDADTMRLQPIGRDKDGLMYWYQLDQDHNVRMYIEEQDDQDGSSWKCIVRNRNELAETLALLRAQIDPVLLKNSSQQEDPSRES---------PTLEDEETKKDEETPKQEASR------------------------GNEKTEADERSMDSRKRSAANALEGPAVKIEKADEKELVKLPVIVKLEKPVPETEDKKIIREES------------------------------------------------------------------------------------------------------------------------------------------------------DSFKENVKPIKVEAKECRVDPKDLKGSLERLGSQEPERADFGSNIKSSQDITEKSTEETEKLKNDQQAKIPLKKREIKLS----------------------------DDFDSPVKGHLCKSATPTKECLKDDVKQEEETCKRVSTISALSHEGKQLMNGEMNDDKVTASLKTEQLETQLCHTKEDSSSIPAKDGSAGLEGSGVECLNSVLTSTKTSELEKEVS---------------------------------------------------------------------------------------------------------------------LGKAVDGSASDVESHSQKGRGEEPGPPNMDMPLEPSEKTTDLSLKSTLSATESCPTKIEEKAPKSKGENHTAGIECLEKVEKAKKTSVDKDIQRLSP-----IPEEVVRGPLESEESGLCEVAETPLPLEMTGAKEKQ---------------TSEKKGVDCLSRGSSEGQSLENASPDILRENSESSRVEMAKLDNAQTSGVEDTSQTKGSVQKNKCKYKLVSEGNSTASEN--------------------------------------------------------TEITSERKKEG---------IKLTIRISSRKKKPDCPPQIVDSESKEEKAGKEEEKTSVGRTLRRSPRIS--------------RPTAKVAEIRDQKADKKRAEGEEGVEGETTSLQTADKKEHLKK------AEKDTNSKASKVKPKG-KVRWTGSRTRGRWKYSSNDESEGSESDKSSAASEEEEG---------------------------------KESEEAVLPDDDEPCKKCGLPNHPELILLCDS--CDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCEKLEEQLQDLDVALKKK--------ERAERRKERLVYVGISIENIIPPQEPEFSEDQEE----------KKKDAKKSKANVLERRSTRTRK-------------------------------------------------CISYRFDEFDEAIDEAIEDDIKEADGGG-VGRGKDISTITGH-------------------------RGKDISTILDEERKENKRPQR-----AAAARRKKRRRLNDLDSDSNLDEEESEDEFKISDGSQDEFVVSDENPDESEE---EPPSNEDSDTDFCSRRLRRHP---------SRPMRQSRRLRRKTQKKKYSDDDEEEEEEEEESEENSRDSESDFSDDFSDEFVETRR--RRSRRNQKRQINYKEDSESDGSQKSLRRGKEIRRVHKRRLSSSESEESYMS--------------------------KNSEDDELTKESKRSIRKRGRSTGEYSEADEEEEEE------GKPSRKRLHRIETDEE-SCDSAHGDADQPARESQASVLPSEQESSKKPYRIESDEEEDFENVGKVGSPLDYSLVDLPSTNGQSPGKAIENLMGKATEKSQTPKDNGTASANLAPNGTSGGQEVGAPEEDEDELLRVTDLVDYVCNSEQL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PWW9-1", "uniprot_id": "E9PWW9_MOUSE", "id": "E9PWW9-1", "name": "", "aln": "-----------------MAAAAAAAAAAAAAAMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDIGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKYLCECQFDDNLKFKNIINEEDADTMRLQPIGRDKDGLMYWYQLDQDHNVRMYIEEQDDQDGSSWKCIVRNRNELAETLALLKAQIDPVLLKNSSQQEDSSRES---------PTLEDEETKKDEETPKQEASK------------------------ENEKTGADERSVDSGKCSAASALEEPAVKTEKADEKELAKLPVIVKLEKPLPETEEKKIIREES------------------------------------------------------------------------------------------------------------------------------------------------------DSFKENVKPIKVEAKECRADPKDLKGSLERLGSQEPERADFGSNIKS-QDIIEKSTEETEKLKNDQQAKIPLKKREIKLS----------------------------DDFDSPVKGPLCKSATPTKEVLKDDIKQEEETCKRVSTISALSHEGKQLVNGEINDDKVIPNFKTEQMEIQLCDTKEDSASIPAKDGNACMEGNGTECLNSVITSTKTSELEKEAP---------------------------------------------------------------------------------------------------------------------LGKGIDSSVPDIESLSQKARLEEPGLLNMDMPLEPSEKATDLSLKPTLSATEPCSTKVEEKAPRSKSENHTPGIECLERVEKAKKTSIDKDIQKLSP-----IPEEVVRGALESEKSGPCEVAETPLPLSMAGAKEKQ---------------TSEKKDVDCS-RGSSESQSLENASPEILKEDSESSREEVAKLDNAQTSGMEDTSETKGSVQKNKFKYKLVSERNSTASEN--------------------------------------------------------TEITSERKKEG---------IKLTIRISSRKKKPDCPPQTVDSESKEEKAGKEEEKASVGRTLRRSPRIS--------------RPTAKVAEIRVQKADKRRADGEDGVEGEPASLQTADKKDHLKK------AEKDTNSKASKVKPKG-KVRWTGSRTRGRWKYSSNDESEGSESDKSSAALEEEEG---------------------------------KEGEEAVLPDDDEPCKKCGLPNHPELILLCDS--CDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCEKLEEQLQDLDVALKKK--------ERAERRKERLVYVGISIENIIPPQEPEFSEEQEE----------KKKDAKKSKANALERRSTRTRK-------------------------------------------------CISYRFDEFDEAIDEAIEDDIKEADGGG-VGRGKDISTITGH-------------------------RGKDISTILDEERKENKRPQR-----AAAARRKKRRRLNDLDSDSNLDEEESEDEFKISDGSQDEFVVSDENPDESEE---EPPSNEDSDTDFCSRRLRRHP---------SRPMRQSRRLRRKTPKKKYSDDDEEEE----ESEENSRDSESDFSDDFSDDFVETRR--RRSRRNQKRQINYKEDSESDGSQKSLRRGKEIRRVHKRRLSSSESEESFMS--------------------------KNSEDDELTKESKRSVRKRGRSTDDYSEADEDDEEE------GKPSRKRLHRIETDEE-SCDNAHGDADQPARDSQPSALPSEQESSKKPYRIESDEEEDFEN--KVGSPLDYSLVDLPSTNGQSPGKAIENLMGKATEKSQTPKDNGTASASLAPNGTSGGQEVGAPEEDEDELLRVTDLVDYVCNSEQL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96T23-1", "uniprot_id": "RSF1_HUMAN", "id": "Q96T23-1", "name": "Remodeling and spacing factor 1", "aln": "----------------------MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKYLCECQFDDNLKFKNIINEEDADTMRLQPIGRDKDGLMYWYQLDQDHNVRMYIEEQDDQDGSSWKCIVRNRNELAETLALLKAQIDPVLLKNSSQQDNSSRES---------PSLEDEETKKEEETPKQEEQK------------------------ESEKMKSEEQPMDLENRSTANVLEETTVKKEKEDEKELVKLPVIVKLEKPLPENEEKKIIKEES------------------------------------------------------------------------------------------------------------------------------------------------------DSFKENVKPIKVEVKECRADPKDTKSSMEKPVAQEPERIEFGGNIKSSHEITEKSTEETEKLKNDQQAKIPLKKREIKLS----------------------------DDFDSPVKGPLCKSVTPTKEFLKDEIKQEEETCKRISTITALGHEGKQLVNGEVSDERVAPNFKTEPIETKFYETKEESYS-PSKDRNIITEGNGTESLNSVITSMKTGELEKETAP--------------------------------------------------------------------------------------------------------------------LRKDADSSISVLEIHSQKAQIEEPDPPEMETSLDSSEMAKDLSSKTALSSTESCTMKGEEKSPKTKKDKRPPILECLEKLEKSKKTFLDKDAQRLSP-----IPEEVPKSTLESEKPGSPEAAETSPPSNIIDHCEKL---------------ASEKEVVECQSTSTVGGQSVKKVDLETLKEDSEFTKVEMDNLDNAQTSGIEEPSETKGSMQKSKFKYKLVPEEETTASEN--------------------------------------------------------TEITSERQKEG---------IKLTIRISSRKKKPDSPPKVLEPENKQEKTEKEEEKTNVGRTLRRSPRIS--------------RPTAKVAEIRDQKADKKRGEGEDEVEEESTALQKTDKKEILKK------SEKDTNSKVSKVKPKG-KVRWTGSRTRGRWKYSSNDESEGSGSEKSSAASEEEEE---------------------------------KESEEAILADDDEPCKKCGLPNHPELILLCDS--CDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCEKLEEQLQDLDVALKKK--------ERAERRKERLVYVGISIENIIPPQEPDFSEDQEE----------KKKDSKKSKANLLERRSTRTRK-------------------------------------------------CISYRFDEFDEAIDEAIEDDIKEADGGG-VGRGKDISTITGH-------------------------RGKDISTILDEERKENKRPQR-----AAAARRKKRRRLNDLDSDSNLDEEESEDEFKISDGSQDEFVVSDENPDESEE---DPPSNDDSDTDFCSRRLRRHP---------SRPMRQSRRLRRKTPKKKYSDDDEEEE-----SEENSRDSESDFSDDFSDDFVETRR--RRSRRNQKRQINYKEDSESDGSQKSLRRGKEIRRVHKRRLSSSESEESYLS--------------------------KNSEDDELAKESKRSVRKRGRSTDEYSEADEEEEEEE-----GKPSRKRLHRIETDEEESCDNAHGDANQPARDSQPRVLPSEQESTKKPYRIESDEEEDFENVGKVGSPLDYSLVDLPSTNGQSPGKAIENLIGKPTEKSQTPKDNSTASASLASNGTSGGQEAGAPEEEEDELLRVTDLVDYVCNSEQL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QHL2-1", "uniprot_id": "A0A8M1QHL2_DANRE", "id": "A0A8M1QHL2-1", "name": "", "aln": "---------------------MAAPGTTSTAALAPAHSPG----FAVVCSFLERYGPVLDLPELSFPQLERYLQDTS------AVPRPLIELHIKLLRKIGKSVTPDRWEKYLVKVCQEFNSTWAWEMERKSYLEMTVECKTDILKYLCECQFDDNLKFKTLINEEDPDTMRLQPIGRDKEGLLYWFQLDQEQNIRVYSEEQDDLDGSSWKLIARNRNDLADTLEQLKAKIEPAVTD---QDKQDAPTS---------PNMETEGVKGEVGDLKNHIPG------------------------QVDFTNSTIR---------SNKIDSISKEIKKETPMDLVKS------EKLTQNLNPRVVIDNRV------------------------------------------------------------------------------------------------------------------------------------------------------STIKTLVK---QEPKDCPKPWNAISVVMPPASIKQEPAIKPETNEDKKETLFEN---LARTIKSDQQAKIPLKKRELKRS----------------------------GGYDVTNH--------------YSNINHNN---------NNLNSNGSISTGGIIVRNPAVLPLKEEQIKGQYP-------------------GDGDKGSMGIITVPQE------------------------------------------------------------------------------------------------------------------------------------PIGKLDINQYIGVGVIKGPIERKRPLDENDSSSNGHHGNGNVLTEVAGT------------------DSVRQSVLVGNTMVKEDGPLTCS-----IPEDLSKDGCNKMLDVSAKVVEESTTEMQTTSVEET---------------IEKSDNKELKNTKTIGEEADVVVQDEGKSKGPKGTRKRRSQKTKSKLQVREDSQKMKLSSNIGEVLKRKTGEGEKNGRNND-------------------------------------------------------EEVSSELQKEG---------IRLKIKIPLHRRTPELQHKEIE-----------ESETGNRRSLRRSARIS--------------KPSPKVANSRDGKQDRKLS--AAQYEDEHVDNEKAKVLSKKVD------TPKPLKGKRRHRRTRWSRIRMKNCKSKVAQEEEAVDDKAENDDNKSEKGDHNSEA---------------------------------ESEQSNEFPPED-ACKHCGLANHPELILLCDL--CDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCERLEEQLQNLDTALKKK--------ERAERRRERLVYVGISVENIIPGPDGDGEDSLME----------KKKDPKKSKN--LGRRSTRTRK-------------------------------------------------SISYRFDDFDEAIDEAIEEDLQDSEGGA-AGGGKPLANVVSQ-------------------------QKSAVN-------RESRRPVK-----PVAPRKKKRRRLNDLDSDSTVDEEESEDEFQLSESMEEDFVVSGDGASDGDVGSYEGSEWGSGESEAENKPASRRT---------GKPAQTRRSRRSKRRPAARRRGSSEEDLLDSEEEEEEEDMETEGSD-CSDTEVDVNR--RRPRRSHNSQVNYYETSESEGSQKPSD-LKHSSHAHRRRLSSSNSEESALS--------------------------KDFKPKVLLQRSDR-VQKKCTPAGEDSKHR------------HKLIKQRPQRSSSEDE---EEDGGETEESEEEERP--------MRKRSNRIETDEEE------------------EEDTRGNVRWKHIR--------------HNGLVAAQQEEE-----EEDDDDEEDEEEFTGVTDLVNFVFDSEQLS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VID9-1", "uniprot_id": "Q9VID9_DROME", "id": "Q9VID9-1", "name": "", "aln": "MAASSAAAAAPTNPIPLPTDSISEECKDDDALTSTLHTCANDPDFAVICAFLQKFGKDLGLNLPNFKHLQEWLTNNN-------DVPELRDLHIKLLRKTRKTVHEKSWESALSKFCFGYSVQDAWEIERFGYRNSSLKVKLRIFRELLESQFERNAKFRAHILTLNADTLRSEPIGRDRLGHAYWLTQDAHCNLRIY---QEHLDEEIWQVVATNRDEFVNLISRLRGNEVVLPSKDIGEADEDTSSSNSCHPKPPPPEQKEEEDDEEVGDEPEKTVPNLKIKLRSPEQEDQKSKKVKPLLISQAKLSSSASPAPTKKRSIEDVDSSPTASQEEQQKKHRPTLLDTKRIKKPSRYESTKDEIEEESGEEDEEEEDEEDSELDEGEEEEDVDSAAADIEEDDDEEDTGEPIEDPTIVVQGQGSGLDCEAIPYNLIGNFDYEDDLEIGEAIADPMLHVIGQGWGTDCLVGNGKNEASVEETSTRTSEPKATFFFGEPGCLKLSPMKQTSKPEAKRGIFDSLSEEKTNGESEKCIVNTPPRNGSELTKTLGDSEETASASAATLEETNICQEANVNKISDDQIKKKESVPVAKRNIQDSTISVIEKNEEISKGRTESEAIEEGVRNRTEVSVLQNNSNESDNSSIQTQDQHKVPADLNNTKKPVTEKCVLESGTVEDKLVINHQQISTNALDTACDEKLSCETESPVPNQHDSKMKSEQETATSAKESVSESSPTDGEDETAKSKCLIDPYAGKTNDKGIIINKIDKAEGVIKTLLQDDPPKDISKSETNTTCLEINISPSAEHRISEKVQTIEPSTSQNLLFEDNGKSGEVDGKSRTSGAVEEISKTSTLLNRKRRLNDSQSALRNSTSESEVHEEEPQDDDPTLDDLDVGGKRIKMRPKTTNAESRRKVEAQKTQIEETTSSSGEDDARIRRKCIAPHTKTKPTLEEIIERKLKKSIEMDLPEKTTEKVMEMPTQLMQKTREATPPIISLSPQKKTPITKPLKKNLLTQLRQEESEEETIPRKRTNSETLVPAIPASNVLCQPDERHRKRRSSEDANEAFSKESSPTEVPPSAVSEKLKRNNEQDIQEEVEDPLAMSVKDSLRSAKDQSPVPEGSARRSGRRGGPAVIHSELPQPKRTRGGARDKMQPEVNAELKQESEDDEKISTKIKSEAKDDPAPESPENRKKPEEKPIKEEPNEEPKPKVGRGRGPRKKREVDTTNIIETNDSETPVRQSRRIAQQKIKEEAERRKQEEVALRTMKQELKKKKKAEKEADPTVLEPSGEESESEASEAEEEARNKKKKKCPGKDGWSSDSEEQPESEEEEEEPPHYETDPGSPLFRSDHEFSPESELEDESQVVPMKRARTVRKENADDLEEEDAEEACQKCGKSDHPEWILLCDTPTCNKGYHCSCLSPVLFYIPEGDWHCPPCQQEQLIAALERQLEQYDTLVAQKQQERILAEEQAERERQELEAATLAAKDENFKSEKEEDEDDRDDMAVGKAEKVKRRRGDGRINRRAAKRGTRRRRGNESDSSHRKSLGSGSRSGSGSDSSSDNSTSFSDSDDEPIYKLRKRRQINVSYRLNEYDDLINSALKKEMDEVAGAGNLGRGKDISTIIEADKEKARRDDLPTEDEVGNKEDGEKDKQKSKSSGSSPSSSEDEVPLKRSNKFKQPPAKKKARKLTTLDVSSEED-HGSDEDFKTSSYSDEDTSQSASGDSDSSLEAYRRPGRGKKQRKAARRAARERRKDRKFVVEESDESEDEDQKRRTTKSKKKKDDSDYTETETEDDDDNELSDNVDSADLCDDTTSESEDGAWNPSSKKKKTVAAKKSNSSGGIARKSPKLKKLATQAEKKVKRLEYSDDDISESDLEEDDDDDEEDEEGVPLSGKGSGKQPRSQPLKPTASSTLTGKGKGKGKAKKKKQVSSEEEDGAASDDRTRTRGRRYAYIEDDDDSSDGGIKPGVHRPDTPPEERQKFIQRQEEIKRMLAEKNAEGAKIAATPRLTPLKSGVTASEKRTPGKAASGDSLSTVPLSVIRQAKVLDIDYLQRKGETIGDLDDVDESELDDAELPDDLPEDMEDAIARMVEEEEQFSAEVAARELPGAEEVLRTTPSKSKQTSRVMPESPAQNSAPSTSGLQEPHRKRLPMPTMHPPLLRHQFPISAGPSHSPASLVPPHAAQGMHPMLQRHLSQTVPPPQAMHLLQNALSAPLGQPLGCGNYGSGPNSAQHLPLVMSMPSAAAAAAHLMQSAVASATARPVETASGNPASDPKPRGRRKKVTPLRDQLQKQQTAAAVTAATSSTTPGSAPSEKVKAQPLFKPHEDAAPSAPASQASVITRMPSLLPPAHGRNHGPPSGLYPSSADLARFYGQVANQQPIPAVPGSRSPSSTSGPPRHLLRPQMPPGLPPPHASLRPTYGPPPPLRGSGPPTSTPSTTTNSRPAYLHGAEHHGGPSGPPMGGVFSSGPPPARHATPHLNPYRAPPIYGNPNYSPRLGGAPGTGSMRPGAVDYVAGPRGYSPYGYYPPPPPLSTPSAHAATSSVIVSAPHTLTPTNHSVPTLTHGKTPPQQTPTQSSGPPPAAAPPPTITSETSSHKPPLASVITSKKLTTLEAYPIRKSPIAVVADVSGPAEPTRSPAPIAEEDSGSAHDTRAPSSATGTAVVGEFSGLVSYFSSQQDDYDT", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. . ***:*:**:::* *.* * .*:. * * :**:**:** *:* . **. * *.* :. ***:*: .* : ::: * ::: * *.**: * **: * :.**:* :*****: * ** * . *:*:* *:. * . *: :. **:::.: : *:.: . : .: : * * : * . : :. : . . : . :: . . :* . : * :. .::. . * . . .: . .. . * : .:: .:*: **::: * . : .: : . : .*. : : . : . . .: . : . : . . . . .* ..: * . :**. . : :. * . . :: .:.. : . .. : . . .:: ::.. : . . . : * : : *:.:* ::*. *: : ..*: : : : :.. * *:. .:. : : ::*: : : .: . :. . . . : : :.: . . . . : . . : . .: :: . .::. . . :. :. : .*::** .:*** ***** *:.*** :** * *: **:*:*.*****:: * **.**:: *. : :* *:***.::.* . :: :: : : .:. : *:: . :*.** *: :***::::*: *:.*::.::.: *.. * ** ::.: : . . *.. * : .. :** *:*. ** .* * . *:::*: *. ::: * .. .:.. . . : . : .: . . * . ... : .:::. . : : :* .* : . .. .:: : : ..* * : *. .:::. : .:. :* *: . . * :. : : .. .: . : * :* :: .. * . . . :. : *:: :. . * : : : . *.: :: ** : : :: ", "identical_positions": 174, "similar_positions": 414, "identity": "6.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-92", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O14654-1", "uniprot_id": "IRS4_HUMAN", "id": "O14654-1", "name": "Insulin receptor substrate 4", "aln": "------------MASCSFTRDQATRRLRG-AAAAAAAALAAVVTTPLLSSGTPTALIGTGSSCPGAMWLSTATGSRS--------------DSESEEEDLP--------------------------------------VGEEVCKRGYLRKQKHGHRRYFVLKLETADAPARLEYYENARKFRHSVRAAAAAAAAAASGAAIPPLIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMVAENESEQESWYLLLSRLILESKRRRCGTLGAQPDGEPAALAAAAAAEPPFYKDVWQVIVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSISIGAHLLTLLSARRHLGLVPLEPGGWLRRSRFEQFCHLRAIGDGEDEMLFTRRFVTPSEPVAHSRRGRLHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIPEGAARGPHRARAFDEDEDDPYVPMRPGVATPLVSSSDYMPMAP-QNVSASKKRHSRSPFE-DSRGYMMMFPRVSPPP-APSPPKAPDTNKEDDSKDNDSESDYMFMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNPFRSSPLGQNDNSEYVPMLPGKFLGRGLDKEVSYNWDPKDAASKPSGEGSFSKPGDGGSPSKPSDHEPPKNKAKRPNRLSFITKGYKIKPKPQKPTHEQREADSSSDYVNMDFTKRESNTPAPSTQGLPDSWGIIAEPRQSAFSNYVNVEFGVPFPNPANDLSDLLRAIPRANPLSLDSARWPLPPLPLSATGSNAIEEEGDYIEVIFNSAMTPAMALADSAIRYDAETGRIYVVDPFSECCMDISLSPSRCSEPPPVARLLQEEEQERRRPQSRSQSFFAAARAAVSAFPTDSLERDLSPSSAPAVASAAEPTLALSQVVAAASALAAAPGIG----AAAAAAGFDSASARWFQPVANAADAEAVRGAQDVAGGSNPGAHNPSANLARGDNQAGGAAAAAAAPEPPPRSRRVPRPPEREDS----DNDDDTHVRMDFARRDNQFDSPKRGR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9Z0Y7-1", "uniprot_id": "IRS4_MOUSE", "id": "Q9Z0Y7-1", "name": "Insulin receptor substrate 4", "aln": "------------MASCSFSGHQALRRLRASAAAAASAALAAVATTPLLSSGTRTALIGTGSSCPGAMWLSTATGSRS--------------DSESEEEDLP--------------------------------------VGDEVCKRGYLRKQKHGHRRYFVLKLETADAPARLEYYRNARKFRHSVRAAAAAAEAAASGAAVPALIPPRRVIILYQCFSVSQRADARYRHLIALFTQDEYFAMVAENESEQESWYLLLSRLILESKRRRCGTLGALPDGEPAALAAAAAAEPPFYKDVWQVVVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRSTVIGPGELWMQVDDSVVAQNMHELFLEKMRALCADEYRARCRSYSISIGAHLLTLLSTRRHLGLLPLEPGGWLRRYGLEQFCRLRAIRERE-EMLFTRRFISPREPPPPFRRGRGHLPRARRSRRAASVPPSLFRRSAPSPGRIPQPEDVPNDRAR---EASGSSSGNTEE----KDKEGEEGNRGDCIPMNNWGSGNGRGSGGGRGSSGQGSSSQGSGGR------QGSGGGQGSGGQGAGGNQCSGNGQGTAGGHGSG-----GGGHGSGGGQRPGDGHGSGGGKNSG------SGKNSD-DGDRGKSVKKRSYFGKFTQSKQQQTLPPPPPPP--PAAGATGGKGKSGGRFRLYFCADRG-TKERKEAKEVRDMETSGGATRGPYRARAFDEDEDDPYVPMRPGVAAPLACSSDYMPMAP-QNSSASTKRHSRSPFE-DSRGYMMMFPRVSPPPPVPSAPKAPDTNKGDDSKDNDSDSDYMFMAPGAGAIPKNPPNAQGGSSSKSWSSYFSLPSPFQSSPLGQSDHSEYVPMLPGKFLGSGLHKEASFSQGTKNVSSKPSTEASFSKPEDKGSSAKPSDDVPPMNKAKEPNHLSFIAKGTQVKPKPLNPTQERREAAGSRDYINIDFIKRERLVLPSSAQGLPDMRGVVTDPAPTAFSGYLNVEFGVPFPNPTIRLSDLLRVLPGANSIPLAGTRWPFP---GSAIGS--IVEAGEYIEVIFNPAMTPAMSFADSAICYDAQTGQIYVVDPFSECCMDVSLSPGRCSEPPPVARLRREEAQERRRPQSRSQSLFASTRAAVSAFPTDSLDRDFPAASAVIAAPAEAPLLAVSRALAVVSALAAAPSIGDVFAGFRAAAGVDSASARGFQPVAG---AQAVREFQDLAAGWNPGALN---HRARGED----LAAGAAAPPPPPRQIWVLRPQERADSEDDDDDDDDIYVRMDFARRDYRK-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FCJ4-1", "uniprot_id": "E7FCJ4_DANRE", "id": "E7FCJ4-1", "name": "", "aln": "MEDRPRLPNHGVMLTLEAQPRRAVTKTSASGISCAAAGEPPSSSSSSSSSSTSTSINNSGCRLPMHLSASSHCQPQRRYHPPYHFKVHHLFPDESPQDAVLRKNLPALQYKVHDSAFCRVLSADTTAAALAAAAACSGGLDRDIWKCGYLRKQKHGHKRFFVLRGPSNLGPSRLEYYDSEKKFRNALKAAASGVTCPAK-----------RVIYLSQCFTVNKRADAKNKYLIALYTKDEYFAVVAESEQEQEEWYLSITELMTEGKK-------GQLDNDELDDGYGTISPGTIFKEVWQVNVKPKGLGQTRNLMGVYRLCLSAKTIHLVKLNSETPAVNLPLMNIRRCGHSESFFFIEVGRSSSIGPGEIWVQVEDSVVAQNMHETILDTMKALKAFP-DFRPRSKSQSSGSNPLPFITTRRHLGNLPPSQTGLQRASRTDSMT---------------------GTPPTGKSRGR-----GQRYRTSSEGEGTQDRPLSSGTGSLVHINTPILSVGR---EESGSCCAHASP-------NQAHHTRSASLPVSHFLSATSPISVSSSSGHGSASDTHTRPSS------SSICGSPSDGGFNSSDEFCPSPCDFRYFHASCT------TPESHGSTPPIRDDYRLTEYMTMD------WHRDGARTFEEESSYMERTFLKLAHSSKPKLGGSLSITQQKATQTSSSFDEPMESKRQQVCSCLLKSAYKSYSELHHPNKPPLLSSECQKKLPK-------DDGYMPMIYSMAS--SPNADYTPMQPRANHPASLDVHPCSSQQSDRYGYMMMLPSDSPSS------------REQAEYDDYMDMSQLTIAEGFSQASPDSLK----------ASYFSLPRSYKAPSREKHEKAEYVPMSPADPMS-------------------PPSPGEYIHMDFGPRLAHPALSPPSADSPS--------------TPPPSQPCYRMCCSSPDHDYLGLNMDN--------LLKDRPPRHSLVAPWNPPNYARPLGCSYGQTSAN-----LDPEKVHGECGDVPLR------------------------TMQHLCISERLPFTHTEPKVIRADPQGRRRHSSETFIPSPATFASGCG-----------IRPSANQNLPEASRWQSSFDSMWSHPDASPNSATGGTPLNTSSSYLNYIALDLREVARVTHDAPRPAHSNLQE-----SDAYAGIDFS----------------------VSGGRANASKD----------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . :* : . . :.*:*. .. ::. **.* *:: .:*. * : *: .: .** :: : :. :: * **********:*:***: : .*:***** . :***::::***:.. ..*. *** * ***:*.:****: ::****:*:*****:***.*.***.*** ::.*: *.*: . *.: . .: : .::*:**** ***:***: ::* **:****: : : :*:**:*..:* : *:.********.:**:*****: *****:*:**:*.******** :*:.*:** * * ** * * *:: *.::::***** :* . * * :.: * . *** .:* * : . : * :.... : . .* * *** ..: : . . . :*:.:: *... * .. .. *..*.:: . .. *. ...* .:..: *. : .. .. *. *.: . . :.. :. .* :*::: .** : . . . . :..: .: .. * :: * :. *. .* :. .. . : ** *:** .:*: .:** ** * * .** . *. *. : * *****:* **.. : : . *: : . : :* * . . :. : :****** .:::.. : :::***** *.. :. *. ..: : ::*: *. :... .* * :* . : . **:.::: : :. * .::: . :: :. .:* . .* * :. .. :.* :: : . * ..* *.: : : :.* . .: . . : . ::. ** ** * : : .* *..: :*: :::. .. * : * **.* : ::.* .: : ", "identical_positions": 254, "similar_positions": 350, "identity": "19.05%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-96", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61083-1", "uniprot_id": "M3K2_MOUSE", "id": "Q61083-1", "name": "Mitogen-activated protein kinase kinase kinase 2", "aln": "MDDQQALNSIMQDLAVLHKASRPALSLQETRKAKPSSPKKQNDVRVKFEHRGEKRILQVTRPVKLEDLRSKSKIAFGQSMDLHYTNNELVIPLTTQDDLDKAVELLDRSIHMKSLKILLVVNGSTQ--ATNLEPSPSPEDLNNTPLGAERKK-RLSVVGPPNRDRSSPPPGYIPDILHQIARNGSFTSINSEGEFIPESMDQMLDPLSLSSPENSGSGSCPSLDSPLDGESYPKSRMPRAQSYPDNHQEFTDYDNPIFEKFGKGGTYPRRYHVSYHHQEYNDGRKTFPRARRTQGTSFRSPVSFSPTD-HSLSTSSGSSVFTPEYDDSRIRRRGSDID---NPTLTVTDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFNPESPETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMELSPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNIKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLPPHVSDYTRDFLKRIFVEAKLRPSAEELLRHMFVHYH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2U5-1", "uniprot_id": "M3K2_HUMAN", "id": "Q9Y2U5-1", "name": "Mitogen-activated protein kinase kinase kinase 2", "aln": "MDDQQALNSIMQDLAVLHKASRPALSLQETRKAKSSSPKKQNDVRVKFEHRGEKRILQFPRPVKLEDLRSKAKIAFGQSMDLHYTNNELVIPLTTQDDLDKAVELLDRSIHMKSLKILLVINGSTQ--ATNLEPLPSLEDLDNTVFGAERKK-RLSIIGPTSRDRSSPPPGYIPDELHQVARNGSFTSINSEGEFIPESMDQMLDPLSLSSPENSGSGSCPSLDSPLDGESYPKSRMPRAQSYPDNHQEFSDYDNPIFEKFGKGGTYPRRYHVSYHHQEYNDGRKTFPRARRTQGTSLRSPVSFSPTD-HSLSTSSGSSIFTPEYDDSRIRRRGSDID---NPTLTVMDISPPSRSPRAPTNWRLGKLLGQGAFGRVYLCYDVDTGRELAVKQVQFDPDSPETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYGALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICLSGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFEAMAAIFKIATQPTNPKLPPHVSDYTRDFLKRIFVEAKLRPSADELLRHMFVHYH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F683-1", "uniprot_id": "E7F683_DANRE", "id": "E7F683-1", "name": "", "aln": "MDEQEALNSIMQDLAVLHRSSRPSV-LSDLAKPKASSPKNQNDVRVKFEYRGEKRILQFPRPVSLEDLSAKAKVAFGQSMDLHYTNNELVIPLSTQDDLDKAVELLDRSVHMKSLKILLVLPSWSQNCVSSKDLLPTHDILDNTDFSAPDKKSMLAHIGSQSTDRSSPPPGYIPDALQQVARNGSFTSINSEGEFIPESMDQMLDPLSMSSPENSASGSCPSLDSPLDSDTYPKSRMPRALSYPDNHQEFPEYDIPVFEKTGKGGTYPRRYHIPFGLQDYSDGRKTFPRARRTQAHGFRSPVSFSPTEQQSPSTSSGSSIFTPELEEPGRRRRGSDIEPSSNPTLSVMDISPPSRSPRAPTNWRLGKLLGQGAFGRVFLCYDADTGRELAVKQVQFDPDSPETSKEVSALECEIQLLKNLFHERIVQYYGCLRDTHEKTLSIFMEYMPGGSIKDQLKSYGALTENVTRKYTRQILEGVCYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASRRLQTICLSGTGIKSVTGTPYWMSPEVISGEGYGRKADIWSIGCTVVEMLTQRPPWAEFEAMAAIFKIATQPTNPTLPPHVSDHCRDFLKRIFVETKQRPAAEDLLRHTFVH--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*:*************::***:: *.: *.*.****:*********:********..***.**** :*:*:*******************:***************:**********: . :* .:. : *: : *:** :.* ** *: :*. . ************ *:*:****************************:******.************.::********* *********.:** *:*** ***********:.: *:*.*************. .:*********: :* *******:**** ::. *******: ****:* *****************************:****.*************:*:********.************:*************.:********* **********:******************** *********************:**:********:***********:****************************:.********::**********************.*******: **********:* **:*::**** *** ", "identical_positions": 496, "similar_positions": 85, "identity": "79.23%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120215-97", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48544-1", "uniprot_id": "KCNJ5_HUMAN", "id": "P48544-1", "name": "G protein-activated inward rectifier potassium channel 4", "aln": "MAGDSRNAMNQDMEIGVTPWD-PKKIPKQARDYVPIATDRTRLLAE-GKKPRQRYMEKSGKCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTVTWLFFGFIWWLIAYIRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINQKSPFWEMSQAQLHQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLP--SPPLLGGCAEAGLDAEAE-QNEEDEPKGLGGSREARGSV--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P48545-1", "uniprot_id": "KCNJ5_MOUSE", "id": "P48545-1", "name": "G protein-activated inward rectifier potassium channel 4", "aln": "MAGDSRNAMNQDMEIGVTSQD-HKKIPKQARDYIPIATDRTRLLTE-GKKPRQRYMEKTGKCNVHHGNVQETYRYLSDLFTTLVDLKWRFNLLVFTMVYTITWLFFGFIWWLIAYVRGDLDHVGDQEWIPCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILLLVQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASIRAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINEKSPFWEMSRAQLEQEEFEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAEMKRSGRLLQYLP--SPPLLGGCAEAGNEAEAE-KDEEGEPNGLSVSQATRGSM--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IAD0-1", "uniprot_id": "A0A0R4IAD0_DANRE", "id": "A0A0R4IAD0-1", "name": "", "aln": "MAGDSRVHMDHDMEIGVTPREQVKKLPKHLRESQ-IPTDRTHLISDPVKKPRQRYVQKDGKCNVHHGNVKETYRYLSDLFTTLVDLRWRLSFFIFTLVYVVNWLFFGFLWWLIALIRGDLLHSDEEGWTPCVENLNSFVSAFLFSIETETTIGYGYRVITEKCPEGIILLMVQAILGSIVNAMMVGCMFVKISQPKNRAETLMFSHNAVISVRDNKMCLMFRVGDLRNSHIVEASIRAKLIRSQQTKEGEFIPLNQTDINIGFDTGDDRLFLVSPLIISHEINEKSPFWEMSRAQMEKEEFEIVVILEGMVEATGMTCQARSSYLDSEVLWGFRFTPVLSLEKGFYEVDYNNFHDIYETNTPTCSAKELSARLKESPLLPHLPLLSPDLRAHTTDPFQTTEDQAKHDADTPPETNNGSANRLEENP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****** *::*******. : **:**: *: *.****:*::: *******::* **********:****************:**:.:::**:**.:.******:***** :**** * .:: * ******..******************:**************:***********:*************:********:*****:**:*:************************:*:****************:**********************:********:**:.:****:*********************:*:*****.******:***********.*** ******:*.****: :.. ** :** ** * . ::. :* : :.: . * . . * . ", "identical_positions": 305, "similar_positions": 74, "identity": "71.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120216-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P56277-1", "uniprot_id": "CMC4_HUMAN", "id": "P56277-1", "name": "Cx9C motif-containing protein 4", "aln": "MPQKDPCQKQACEIQKCLQANSYMESKCQAVIQELRKCCAQYPKGRSVVCSGFEKEEEENLTRKSASK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IZJ0-1", "uniprot_id": "A0A0R4IZJ0_DANRE", "id": "A0A0R4IZJ0-1", "name": "", "aln": "MSQKDPCQKQACAIQKCLQANRYIESRCEDVIRAMKKCCELHTGENSVCCSGFAKENKPTDPKT----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.********** ******** *:**:*: **: ::*** :. .** **** **:: . .:. ", "identical_positions": 36, "similar_positions": 16, "identity": "52.94%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120220-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q53FA7-1", "uniprot_id": "QORX_HUMAN", "id": "Q53FA7-1", "name": "Quinone oxidoreductase PIG3", "aln": "-------MLAVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILGLEASGHVAELGPGCQGHWKIGDTAMALLPGGGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLVTAGSQKKLQMAEKLGAAAGFNYKKEDFSEATLKFTKGAGVNLILDCIGGSYWEKNVNCLALDGRWVLYGLMGGGDINGPLFSKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQEAHKYMEANKNIGKIVLELPQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32T3Z8-1", "uniprot_id": "A0AB32T3Z8_DANRE", "id": "A0AB32T3Z8-1", "name": "", "aln": "MDKEKTSMLALCVEAG----KMNVKHVPRPEAKDGQLLIKVAATALNRADLLQKRGLYPAPPGESEILGLEASGVISGVGPGVKGNWTLGSKVMALLGGGGYAEYVAVPEELVMEVPSHLSLYEAAALPETWLTAHQLLHFIAKVRPNETVLIHAGASGVGTAAVQLVRLSHAIPVVTTGSPEKIRFAEQIGAALGINYKEEDISEKVLQFTKGKGADVILDCIGGNYWEKNISSLAVDGRWVLYGTMGGKTSDGDLLGKLLRKRGHLLCSLLRSRSLQYKAELVQSFTQQVLPHFKSTDSP-LRPVIDSMFSMEDAEEAHQHMEANKNIGKIIIKIGKP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***: .: :: **.*.:*.. :*::*:****:*******:*::* * .*** *:******** :: :*** :*:*.:*...**** *** *:**:*** *:* :*. *:* :***:**:****.****::.:*:..: ****** *******:**.*:: ***:**:** :*:::**::*** *:***:**:** .*:**** *.::*******.*****:..**:******** *** :* *:.*** *** *: ******. :** **::**:*:****.: .. * **:* ::.: : :***::**********:::: : ", "identical_positions": 184, "similar_positions": 101, "identity": "54.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120221-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AC12-1", "uniprot_id": "A0A8I6AC12_RAT", "id": "A0A8I6AC12-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNAESQNVDHEFYGEKHASLGRKHTSRSLRLSHK------------------------------------TRRTRHASSGKAIHRNSEVSTRSSSTPSIPQSLAENGLEPFS-------------------QEGALDDFGDPIWVDRVDMGLRPVSYTDSSVTPSVDGSIVLTAASVQSMPDSEESRLYGD-----DAAYLAEGGRRQRPYTSNGPTFMETASFKKKRSKSADIWREDSLEFSLSDLSQEHLTSNEEILGSAEEKDCEEARGMETGASPRQLSTCQRANSLGDLYAQKNSGVKANGGPRNRFSSYCRNLVSDIPDLAKHKMPP--------------------------------AAVETPTYSNYNTLPCRKSHCLSEGATNPQISLSKSMQGRRAKTTQDVNTGEG----SEFADSGIEGATTDTDLLSRRSN-------ATNSSYSPPTGRAFVGSDSGSSS-----------TGDAARQGVYENFRRELEMSTTNSESLEEAGSAHSDEQSSGTLSSPGQSD-----ILLTAAQGTVRKAGALAVKNFLVHKKNKKVESATRRKWKHYWVSLKGCTLFFYESDGRSGIDHNSVPKHAVWVENSIVQAVPEHPKKDFVFCLSNSLGDAFLFQTTSQTELENWITAIHSACAAAVARHHHKEDTLRLLKSEIKKLEQKIDMDEKMKKMGEMQLSSVTDAKKKKTILDQIFVWEQNLEQFQMDLFRFRCYLASLQGGELPNPKRLLGFASRPTKVAMGRLGIFSVSSFHALVAARTGEIGVRRRTQAMSRSASKRRSRFSSLWGLDTTSKKK-QGRPTINQVFGEGTDAVKRSLEGIFDDSVPDGKREKEVVLPSVHQHNPDCDIWVHEYFTPSWFCLPNNQPALTVVRPGDTARDTLELICKAHQLDHSAHYLRLKFLMENKMQFYVPQPEEDIYELLYKEIEICPKVTQNIHIEKSDAAADNYGFLLSSVDEDGVRRLYVNSVKETGLASKKGLKAGDEILQINNRAAGTLNSSMLKDFLSQPSLGLLVRTYPEPEGGVELLENPPHRVDGPVDLGESPLTFLTSNPGHSLSSEQGSSAETAPEEGEGPDLESSDETDHSSKSTEQVTAFCRSLHEMSPSDS-----SPSPQDATS-PQLATTRQLSDADKLRKVICELLETERTYVKDLNCLMERYLKPLQKETFLTQDELDVLFGNLTEMVEFQVEFLKTLEDGVRLVPDLEKLEKVDQFKKVLFSLGGSFLYYADRFKLYSAFCASHTKVPKVLVKAKTDTAFKAFLDAQNPRQQHSSTLESYLIKPIQRVLKYPLLLRELFALTDAESEEHYHLDVAIKTMNKVASHINEMQKIHEEFGAVFDQLIAEQTGEKKEVADLSMGDLLLHTSVIWLNPPASLGKWKK--EPELAAFVFKTAVVLVYKDGSKQKKKLVGSHRLSIY-EEWDPFRFRHMIPTEALQVRALPSADAEANAVCEIVHVKSESEGRPERVFHLCCSSPESRKDFLKSVHSILRDKHRRQLLKTESLPSAQQYVPFGGKRLCALKG--------ARPAMSRAVSAPSKSLGRRRRRLARNRFTIDSDAISASSPEKEP---------------------QQPPGG-------GDTDRWVEEQFDLAQYEEQD-DIKETDILSDDDEFCESAKGASVDIDLQEQLQAASISQRAR------GRKTLDSHASRMTQLKKQAALSGINGGLESASEEVIWVRREDFAPSRKLNTEI----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60610-1", "uniprot_id": "TIAM1_MOUSE", "id": "Q60610-1", "name": "Rho guanine nucleotide exchange factor TIAM1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNAESQNVDHEFYGEKHASLGRKHTSRSLRLSHK------------------------------------TRRTRHASSGKAIHRNSEVSTRSSSTPSIPQSLAENGLEPFS-------------------QEGALDDFGDPIWVDRVDMGLRPVSYTDSSVTPSVDGSIVLTAASVQSMPDSEESRLYGD-----DATYLAEGGRRQCPYTSNGPTFMETASFKKKRSKSADIWREDSLEFSLSDLSQEHLTSNEEILGSAEEKDCEEARGMETEASPRQLSTCQRANSLGDLYAQKNSGVKANGGPRNRFSSYCRNLVSDIPDLAKHKMPPA-------------------------------AAEETPPYSNYNTLPCRKSHCLSEGATNPQISLSKSMQGRRAKTTQDVNTGEG----SEFADSGIEGATTDTDLLSRRSN-------ATNSSYSPPTGRAFVGSDSGSSS-----------TGDRARQGVYENFRRELEMSTTNSESLEEAGSAHSDEQSSGTLSSPGQSD-----ILLTAAQGTVRKAGALAVKNFLVHKKNKKVESATRRKWKHYWVSLKGCTLFFYETDGRSGIDHNSVPKHAVWVENSIVQAVPEHPKKDFVFCLSNSLGDAFLFQTTSQTELENWITAIHSACAAAVARHHHKEDTLRLLKSEIKKLEQKIDMDEKMKKMGEMQLSSVTDSKKKKTILDQIFVWEQNLEQFQMDLFRFRCYLASLQGGELPNPKRLLAFASRPTKVAMGRLGIFSVSSFHALVAARTGEIGVRRRTQAMSRSASKRRSRFSSLWGLDTTSKKK-QGRPTINQVFGEGTDAVKRSLEGIFDDTVPDGKREKEVVLPSVHQHNPDCDIWVHEYFTPSWFCLPNNQPALTVVRPGDTARDTLELICKTHQLDHSAHYLRLKFLMENRVQFYIPQPEEDIYELLYKEIEICPKVTQNIHIEKSDAAADNYGFLLSSVDEDGIRRLYVNSVKETGLASKKGLKAGDEILEINNRAAGTLNSSMLKDFLSQPSLGLLVRTYPEPEGGVELLENPPHRVDGPVDLGESPLAFLTSNPGHSLSSEQGSSAETAPEEGEGPDLESSDETDHSSKSTEQVAAFCRSLHEMSPSDS-----SPSPQDATS-PQLATTRQLSDADKLRKVICELLETERTYVKDLNCLMERYLKPLQKETFLTQDELDVLFGNLTEMVEFQVEFLKTLEDGVRLVPDLEKLEKVDQFKKVLFSLGGSFLYYADRFKLYSAFCASHTKVPKVLVKAKTDTAFKAFLDAQNPRQQHSSTLESYLIKPIQRVLKYPLLLRELFALTDAESEEHYHLDVAIKTMNKVASHINEMQKIHEEFGAVFDQLIAEQTGEKKEVADLSMGDLLLHTSVIWLNPPASLGKWKK--EPELAAFVFKTAVVLVYKDGSKQKKKLVGSHRLSIY-EEWDPFRFRHMIPTEALQVRALPSADAEANAVCEIVHVKSESEGRPERVFHLCCSSPESRKDFLKSVHSILRDKHRRQLLKTESLPSAQQYVPFGGKRLCALKG--------ARPAMSRAVSAPSKSLGRRRRRLARNRFTIDSDAISASSPEKEP---------------------QQPAGG-------GDTDRWVEEQFDLAQYEEQD-DIKETDILSDDDEFCESLKGASVDRDLQEQLQAASISQRAR------GRRTLDSHASRMTQLKKQAALSGINGGLESASEEVIWVRREDFAPSRKLNTEI----------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13009-1", "uniprot_id": "TIAM1_HUMAN", "id": "Q13009-1", "name": "Rho guanine nucleotide exchange factor TIAM1", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNAESQHVEHEFYGEKHASLGRKHTSRSLRLSHK------------------------------------TRRTRHASSGKVIHRNSEVSTRSSSTPSIPQSLAENGLEPFS-------------------QDGTLEDFGSPIWVDRVDMGLRPVSYTDSSVTPSVDSSIVLTAASVQSMPDTEESRLYGD-----DATYLAEGGRRQHSYTSNGPTFMETASFKKKRSKSADIWREDSLEFSLSDLSQEHLTSNEEILGSAEEKDCEEARGMETRASPRQLSTCQRANSLGDLYAQKNSGVTANGGPGSKFAGYCRNLVSDIPNLANHKMPPA-------------------------------AAEETPPYSNYNTLPCRKSHCLSEGATNPQISHSNSMQGRRAKTTQDVNAGEG----SEFADSGIEGATTDTDLLSRRSN-------ATNSSYSPTTGRAFVGSDSGSSS-----------TGDAARQGVYENFRRELEMSTTNSESLEEAGSAHSDEQSSGTLSSPGQSD-----ILLTAAQGTVRKAGALAVKNFLVHKKNKKVESATRRKWKHYWVSLKGCTLFFYESDGRSGIDHNSIPKHAVWVENSIVQAVPEHPKKDFVFCLSNSLGDAFLFQTTSQTELENWITAIHSACATAVARHHHKEDTLRLLKSEIKKLEQKIDMDEKMKKMGEMQLSSVTDSKKKKTILDQIFVWEQNLEQFQMDLFRFRCYLASLQGGELPNPKRLLAFASRPTKVAMGRLGIFSVSSFHALVAARTGETGVRRRTQAMSRSASKRRSRFSSLWGLDTTSKKK-QGRPSINQVFGEGTEAVKKSLEGIFDDIVPDGKREKEVVLPNVHQHNPDCDIWVHEYFTPSWFCLPNNQPALTVVRPGDTARDTLELICKTHQLDHSAHYLRLKFLIENKMQLYVPQPEEDIYELLYKEIEICPKVTQSIHIEKSDTAADTYGFSLSSVEEDGIRRLYVNSVKETGLASKKGLKAGDEILEINNRAADALNSSMLKDFLSQPSLGLLVRTYPELEEGVELLESPPHRVDGPADLGESPLAFLTSNPGHSLCSEQGSSAETAPEETEGPDLESSDETDHSSKSTEQVAAFCRSLHEMNPSDQ-----SPSPQDSTG-PQLATMRQLSDADKLRKVICELLETERTYVKDLNCLMERYLKPLQKETFLTQDELDVLFGNLTEMVEFQVEFLKTLEDGVRLVPDLEKLEKVDQFKKVLFSLGGSFLYYADRFKLYSAFCASHTKVPKVLVKAKTDTAFKAFLDAQNPKQQHSSTLESYLIKPIQRILKYPLLLRELFALTDAESEEHYHLDVAIKTMNKVASHINEMQKIHEEFGAVFDQLIAEQTGEKKEVADLSMGDLLLHTTVIWLNPPASLGKWKK--EPELAAFVFKTAVVLVYKDGSKQKKKLVGSHRLSIY-EDWDPFRFRHMIPTEALQVRALASADAEANAVCEIVHVKSESEGRPERVFHLCCSSPESRKDFLKAVHSILRDKHRRQLLKTESLPSSQQYVPFGGKRLCALKG--------ARPAMSRAVSAPSKSLGRRRRRLARNRFTIDSDAVSASSPEKES---------------------QQPPGG-------GDTDRWVEEQFDLAQYEEQD-DIKETDILSDDDEFCESVKGASVDRDLQERLQATSISQRER------GRKTLDSHASRMAQLKKQAALSGINGGLESASEEVIWVRREDFAPSRKLNTEI----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQ65-1", "uniprot_id": "A0A8M3AQ65_DANRE", "id": "A0A8M3AQ65-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGNAESHSGGHGYYGDGQRQLSRKHMSRSLRLSSKQ-----------------------------------TYCTRRTPSGKPEHRNSETSTRSSSTPSIPQSLADHGLEPFN-------------------DSDLLPDFSSPIWVDRVAMNLRPMSFHNQ-------------------PPHSPAVKPPEE-----NAQVQHTRSPTTRDASQDG--------FKKKRSKSADMWREDSLEVSLSDLSQEHMTSTEEMAD-----------------TPDTHSAQDRANSLDELYGTKPS-----------HGRYARWHKGGAGDEEKMMMSP--------------------------------CEDDGAAYGAF-TLPCRRSHCLSEGPTNQQG----VMQGRRAQTIQDVTAADG----SDYEDSGIDGVTVADSELSQHQSRRYKTMSVSFSAYSTPAGGAFTGSDSGSSSGAAA-------TNTDNTQGVYENFRQELEQSVCPAEAPEDRSCAFSDEQSSVTLSSAYHTHTD-PLLSVSAVQGTVRKAGRLAVKNFLVHKKNKKVELAPRRKWKSYWVSLKGCTLFFYETDGRSGIDHNSVPKHAVWAENSIVQAVPEHPKKDFVFCLSNSLGDSFLFQTCSQTELENWITGIHSACAAAVARQHHREDTVRLLRAEIRKLEQKIDMDEKMKKMGDMQLSAVTDAKKRKTILEQIFLWEQNLEQFHMDLFRFRCYLSSLQGGELPNPKRLLAFASRPTKLAMGRLGIFSVSSFHALVAART-ESGVRRRTQAMSRSTSKRKSRFSSLWGLDTHSKRKSKGHPSIDQVFAEGDDPVKSPLEGMFEGSSSETMKDTKTPVKGLPRPNTDHDIWSRDHLTPSWVLLPNDQPVLAIIQPGESALDMLETICKAHQLDATKHYVRLKFLIENQVQFYIPKPEEDIYDLLYKEIELCCKIRKVIQFDRDESCMIGYGFSISVVEEDGVQQLYITDVRAGGLAFAKGLNAGDEILQLNGKDSRTLTFADMKVAFAQVSLSLTVNTLPPVER-RQLCYLPPRRSDAVDNLYTD---IFSQSQEEILDDGVGLIVETSGDSLDD-DSELFAEFDDYGKSTEQVAAFCRSLHEMNPSSSESVSSSSVPESSSLPPSTATPRQLSDADKLRKVICELVETERTYVKDLNCLIGRYLTPLQKESFLTQDELDVLFGNLPEMLEFQVEFLKTLEDGTRLVPDLEKLERVEEFKKILFSLGGSFLYYADRFKIYSAFCASHTKVPKVLVKAKTDAAFKAFLDERNPKQQHSSTLESYLIKPIQRVLKYPLLLRELHSLTDPDSEEHYHLNVAMKAMNTVASHINEMQKIHEEFGAVFDLLISEQTGEKKEVADLSMGDLLLHSSVTWINPSSSLGKCKK--EPQLATFVFKTAVVFVCKDYSKQKKKMGGSHRASVSGEEKDPFRFRHMIPTDALQVRTLSNTDGESAAVCEIVHIKSESEGRPERVFQLCCSSPESKKDFLKTVHSILRDKQRRQLLKTESLPLSQQYVPFGGKRLCALKG--------ARPAMNRAVSAPSRTLGRRK--LVRNRFTIDTDIVFDTEPDSDSPDSQ---------------HAQQTIGVP-----AGDTDRWVEEQFDLQRYEEQEQDVKETDILSDDEDFCPSAMSPSTEPLLSTLSLEGDTAEEEEEAEEEDSRKDCKSQHAKLSDVGKQCAMSVASVDEQATSDDVVWVRRDSGAENETQDESQS---------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P91621-1", "uniprot_id": "SIF1_DROME", "id": "P91621-1", "name": "Protein still life, isoform SIF type 1", "aln": "MGNKLSCSCAPLMRKAYRYEDSPWQSSRRRDGHLLSSFRLWAEVFHVSASGAGTVKWQQVSEDLVPVNITCIQDSPECIFHITAYNSQVDKILDVRLVQPGTRIGQASECFVYWKDPMTNDTWGLNFTSPIDAKQFRECCSPSFKFSRKASSSYSLKLDPPGKGKVKAKRKPLSTPASPSRVRQEPQCTCMSAEQYARLRTDPRVRGSSTLPRNVGSHRITDVDGQQQVGSGKVVSAVSSTSLYDNVASGGPGTNQGADTLPRQMKGGQQDRQDVANSGVNTNTPGVIVTGVGNVGSDMCGQNHVGSQVGNDDPAACQMDMDLSKSEGTQAGGGLHQSVGTCTSSSKGTGTRNKDFGDDMTRDAHSHDMHQHNVINNNTRRKTKSTEDMNVDTSTLKRMLKPMPSTESPVTSPEMGRRRYNYYNANAAQTLGHPPHMHQHGMAMGMGGGGGGGHHIMNNNTMGRASSQSSRFSGSRSSHEIGRGYPPRNLYLELERERSCIEGSPPSDNVMFDNQCYATTPSSSNGNSDQDQSYGQQQSSGQHPQQQQGPPQRSSRHQHHHQQAPNVTPTPGSPTSRLLLEYEMHLRNTLAKGMDAESYSLHTFEALLSQSMENLANAKSSTLPLPPHRPLSTIRDKERDRDRDGYYSDRNELIRERERERDRGYLSDHNSSFSNSRCASCIGESARAQWFRHSDGWRSGSSTIGSGSGHGMMTQQIPGSGHKRSPWDSLPSLRQDSSLNDSGYKSARADSLEQRAEFIRQDSLRSEYLSDRESRYGIVQQASIESTDSRMCYLTSSEISDDDRMSLTTAVSDEDDGESVMASPYKAKATGTAASSFNCTGAVRKAGFLSVKKWLLR-KKHQIELARKRGWKGYWVCLKGTTLLFYPCDSREGRSVEAAPKHLIIVDGAIMQPIPEHPKRDYIFCLSTAFGDAYLFQAPCQVELENWVNSIHSACAAAFARHRGKTGTLHLLQEEIFRLEKAIESDHKLKHMAELQQSVVTDQETRHQIQTQILQWEENLERLHCEQFRLRCYMASLQSGELPNPKSLLTHVSRPTKNTLNKLGVFTVSSFHAFICARS--PSLLNNLLAGRGATKRRPPMLSRSNSGSSRRSMQMNSRDEPEKTFKVAMPDNAYSTVYLRDAMSVEEFLASACARRNLNPMEHFVRVKKRRDMEDHNYFVPHRNDLIENYLHNHEFVEVCMKILYQVELQRTTLEQMWGFSVEAELIENAERQDE---LCCYVSRVEDKSVAMHNGIIKGDEIMVINGAIVSDLDMMYLESVLQEEQSLSMMMRSSRTEPPDLVGIMRVTDDMIDSLVCPPPPTDPPVMSEEMITG--------LIVPAPGWNGTSKDLYSP---EAESSPATSFVDPAAMAAQLAVGGVGGVVVGGLGVAKPTSRTSSFEIENLLKTAEQETRKS---SPTGSVTSSVSTTALTPSRQLTDAEKLRKVVMELVDTERTYVKHLNNLLEHYLEPMKRETFLSNAEINALFGNIHEIVTFQRQFLQNLEESLDLEPDFNKFEHCGQFRNVLFAIGSAFLYYVNHFKLYSSFCASHSKAQKVLHPNEGNHALQEFLAARNPKQQHSSTLESYLIKPIQRILKYPLLLQQMRNLTDTRADEHVHLCEALKGMEKVAEHINEMQRIHEEYGAIFDHLFRQHQKSCKQPIDLSPGDLLYYGGVEWLNISDFLGKIKKGLELHAMCFVFKSAVVFLCKERLRQKKKLMGVSSKNAT-NEVEIIRYQVLIPVTEVQVRASSAKDMDSHFLWELIHLRSQLQRRSEKVYVLSNSTADFRNAFLKTIRQIIRESVRNMSIPMKNFGGSSGSVSGHSSQGMGSMGYPGNSQTLERPKQQITIVHGSHTLGKPKKKSGSQRHSAGNIDYDNLSGSQEADDLPPSVGVVHYASGHTHGQQMQPAGFRGRSKTVGDVTEITCSSPEPHQQQQQQQQQQQQLMQQGHAHAHPHPHPHPREPPPPPIRQPHLHHHSSDIERIDPGTKSEGEEDSQQGTIRPKATLGRTPNHLTLSTTSTLSVGSTGSQARLIQSSHPPASYQPVLMKDLGSPVWKPRDMINLGTDPQSTTRKDDVKN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :**. *. : . *. . . . .: ** . :: . : :.*:. .*:*:. .: * .. *:*: : . :. * :.: * : . . . : : : : . . ..*:: ::. . . .: * :* . : :* :: : .* . . . : . :. * . . .*:* * . : :* *: : . . .: .** . . ::.. : : * * .** *. . :.. ..: . . : . .. .:::.. .::*. ::. *:***** *:**::*:: *::::* * :* ** ***.*** **:** *.*.* . :: *** : .:.:*:*.:*****:*::****.::**::***: .*.*****:..******:*.**:: : .*::**: ** :**: *: *.*:*:*.::* * *** :.:: * **: **:***::: : **:***::***.******* ** ..***** ::.:**:*:******::.**: .: .. * ::.:* . :* . .: . : :.: ::.* . . : : : . .: : : : : :*: : : .. : * :*: : * :* .: : :* * . .: : :.: * :* :: :. : . : . :. * : :. . :. : * * .* . :* .. : . . .: : . . .:::. . * .. .. : .: . :. ***:**:*****: **::*******.** *: :** *:::*:**:: *::.****: *:: ** :**:.**:. * **::*:*: :*:::**::*.:****.::**:**:*****:*. *** : : *:: ** :**:*****************:*******::: ***. ::** ** *:* *:.**.******:****:**:** *: :: . *: *** **** : * *:* . *** ** * . ****:***:: *: :****: * . :: : :*:: :**. :***: . * :: : *::*::*: : *.*:*: *. *:.: :: ***:::.*:*:. *. : :.: :. *. ..: . * ** . :: *::**: : :*.: .. . ..:. *. * **. . . .. : : ::*: : :: : ... . . : . . : .. :: : :.::. :: ..: * . . ", "identical_positions": 361, "similar_positions": 495, "identity": "17.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120221-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LN97-1", "uniprot_id": "F1LN97_RAT", "id": "F1LN97-1", "name": "", "aln": "-MDPERCAPFA-----VGPAAGPYAAARDEAPGPQGTPDAAPHLRPAPPRGPRLSRFP--ACGPLEPYLPEPAKPP-------AKYLQDLG----PGPVLNGGHFYKGSSEAEEKA-SKAASFPQLPVDCRGGPRDGPSNVQGSPGPCLASLSVPLSPGLPDSMELAKSKSKK-------RRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQ--------EGRNPFTTAYDISVLPRTDSHPQLQNSLWSS----PGSGSPGGPCLMPPEGIPSPCMSPYSHS---HGNVAGFMGVPASP-------------AAHP---GIYSIHGFPPALGGHSFEPSPDGDYKSPSLVSLRMKPKEPP-------------SLLNWTT-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O70137-1", "uniprot_id": "ALX3_MOUSE", "id": "O70137-1", "name": "Homeobox protein aristaless-like 3", "aln": "-MDPERCAPFS-----VGPAAGPYAAAGDEAPGPQGTPDAAPHLHPAPPRGPRLSRFP--ACGPLEPYLPEPAKPP-------AKYLQDLG----PGPVLNGGHFYEGSAEAEEKA-SKAASFPQLPVDCRGGPRDGPSNVQASPGPCLASLSVPLSPGLPDSMELAKTKSKK-------RRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKMQ--------EGRNPFTTAYDISVLPRTDSHPQLQNSLWPS----PGSGSPGGPCLMSPEGIPSPCMSPYSHS---HGNVAGFMGVPASP-------------AAHP---GIYSIHGFPPALGGHSFEPSPDGDYKSPSLVSLRMKPKEPP-------------GLLNWTT-------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95076-1", "uniprot_id": "ALX3_HUMAN", "id": "O95076-1", "name": "Homeobox protein aristaless-like 3", "aln": "-MDPEHCAPFR-----VGPAPGPYVASGDEPPGPQGTPAAAPHLHPAPPRGPRLTRFP--ACGPLEPYLPEPAKPP-------AKYLQDLG----PGPALNGGHFYEGPAEAEEKT-SKAASFPQLPLDCRGGPRDGPSNLQGSPGPCLASLHLPLSPGLPDSMELAKNKSKK-------RRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWFQNRRAKWRKRERYGKIQ--------EGRNPFTAAYDISVLPRTDSHPQLQNSLWAS----PGSGSPGGPCLVSPEGIPSPCMSPYSHP---HGSVAGFMGVPAPS-------------AAHP---GIYSIHGFPPTLGGHSFEPSSDGDYKSPSLVSLRVKPKEPP-------------GLLNWTT-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PL59-1", "uniprot_id": "A0A8M9PL59_DANRE", "id": "A0A8M9PL59-1", "name": "", "aln": "-METESSLSFSSPPNRITPDNSPGLEHNSSSFFQCDDLQKSPHLALAHRHEFFMGRYA--DGGSADFTHGVSSTTPRASPGKHTKYLENINQDQKPSITEKNSSFYETNSDAGDKTLSKPLGYPALDSECCGKLKEASNGLTGDS--------------IADSIDLS-GKNKK-------RRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTELTEARVQVWFQNRRAKWRKRERYGKMQ--------EVRNHFAATYDISLLPRSDTY-QMQNSLWPSGAGATGAGGASSACVLGTENMPSSCMSPYPHP---HGNLPGLMGMSASPGHHHHHHHHHHHPSHHPSINGIYSLHGFPGSLGAHTFEAGPESEYKPSGLVALRMKTKDPG-------------SLLSWPT-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W2P8-1", "uniprot_id": "Q9W2P8_DROME", "id": "Q9W2P8-1", "name": "", "aln": "MMTTTTSQHHQ-----HHPIMPPAMRPAPVQESPVSRPRAVYSIDQILGNQHQIKRSD--TPSEVLITHPHHGHPH---------HIHHLHS---SNSNGSNHLSHQQQQQHSQQQHHSQQQQQQQQLQVQAKREDSPTNTDGGLDVDNDD---ELSSSLNNGHDLSDMERPRKV-----RRSRTTFTTFQLHQLERAFEKTQYPDVFTREDLAMRLDLSEARVQVWFQNRRAKWRKREKFMNQDKAGYLLPEQGLPEFPLGIPLPPHGLPGHPGSMQSEFWPPHFALHQHFNPAAAAAAG--LLPQHLMAPHYKLPNFHTLLSQYMGLSNLNG-IFGAGAAAAAAAASAGYPQNLSLHAGLSAMSQVSPPCSNSSPRESPKLVPHPTPPHATPPAGGNGGGGLLTGGLISTAAQSPNSAAGASSNASTPVSVVTKGED", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04116-1", "uniprot_id": "YHP1_YEAST", "id": "Q04116-1", "name": "Homeobox protein YHP1", "aln": "-MESRNTVLPSLPNIITGTSNSPFQLHTLPNTNFPSDDQGDIRLPPLAASAHIVRPVVNIYKSPCDEERPKRKSPQ------AVDFLSQRVTTSMTPLSKPKKLSSHSPFTPTVRVCSKEQPPQSMHSYKKVNILTPLSAAKAVLTPTTRKEKKRSFAFITHSQETFPKKEPKIDNARLARRKRRRTSSYELGILQTAFDECPTPNKAKRIELSEQCNMSEKSVQIWFQNKRQAAKKHKNSGNTS----------HCKVHSNDSMSMISYSDAALEITSTPTST-----KEAITAELLKTSPANTSSIFEDHHITP----CKPGGQLKFHRKS----------------------VLVKRTLSNTGHSEIIKSPKGKENRLKFNAYERKPLGEV-------------DLNSFKN-------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . * . : : . . .: . . . : . . . : .. : : : **.* ::::* *: .*:: *: * :*: : :::* **:****:* :*::. : . . :. .. .: . .. .. .. : : . :: . . .. : : . . .* . ", "identical_positions": 21, "similar_positions": 75, "identity": "4.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120221-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZDF3-1", "uniprot_id": "D3ZDF3_RAT", "id": "D3ZDF3-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPHIPEDEEPPGE-----PQAAQT---QDSPSAGPFCSP-PTIILTGDASSPGGETDTNLVKRAPSPHRRLSHRHLKVSTASLTSVDPLGHVIDLVNDQLPDISISEEDKKKNLALLEEAKLVSERFLTRRGRRSRSSLGDAPSAVSPNLSSGASPASSRSCSFTISTPPGFDTCSGPQSPLPGSPAQQKGHEDDVFSSHLGEPNASKGLADRKQNDQRKVSQGRLAPRSPTVEKSKELSVEQKENFDPLQHLEATPMAQTSGASVSGKMALNSPQPGPAEMELGRQLLKTAREDNPLPRTTVQGSGGTASPHSQGQGSAGELMGPKAGSKAEPRPPVSRPPLIRGVSWDSSPEEPGPLLQKVLAKLPLAEEEKRFPGKA--KPAKPPGLKDFQIQVQPVRMQKLTKLREEHILMRNQNLVGFKLPELSEAAEQDKGVSSELAPAAEEEESKSGLDVMPNISDILLRKLRVHKSLTGSAPPLTEKEVENVFVQLSLAFRNDSYTLESRINQAERERNLTEENTEKELENFKASITSSASIWYHCEHRETYQKLLEDIAVLHRLAARLSSRAEVVGAVRQEKRMSKATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSCG----PSEDGVPRTARSMSLTMGKNMPRRRVSVAVVPKFNALNLPGQAPSSSP--MP-SLPALSESTNGRSSISTSPVLPALLENGKTNAEANCEVCA-PVPLPSYPEETSQEAKARAEEEAYNKGYQEGVKKTEELQDLKEEEEE-QKAESPQEPEEVEETQEDEKDQRSSKLEELVHFLQVMYPKLCQHWQVIWMMAAVMLVLSVVLGLYSSYNSCTEQADGPPGRSTCSAAQRDSWWSSGLQQELPAEQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WUX5-1", "uniprot_id": "IRAG1_MOUSE", "id": "Q9WUX5-1", "name": "Inositol 1,4,5-triphosphate receptor associated 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGRSLTCPFGISPACGAQASWSIFGVGTAEVPGTHSHSNQAAAMPHIPEDEEPPGE-----PQAAQT---QDSPSAGPFPSP-PTIVLTGDASSPEGETDKNLVNRAPSPHRRLSHRHLKVSTASLTSVDPSGHVIDLVNDQLPDISISEEDKKKNLALLEEAKLVSERFLTRRGRKSRSSLGDSPSAVSPNLSSGASPASSRSCSLTISTSPGLDICSGPQSPLPGAPPQQKGHEDGVSSPCPGEPNVSKGLADLKQNDQRKVSQGRLAPRSPTVEKTKELTVEQKENFDPLQHVEATPMAQASGASISGKMALNSPQPGPAEMELGRQLLKTAREGNPLPRTTAQGSGGTVSPHSLGQGSAGEPMGPKAGSKAELRSPVSRPPLIRGVSWDSSPEEPGPLLQKVLAKLPLAEEEKRFPGKA--KPAKPPGLKDFQIQVQPVRMQKLTKLREEHILMRNQNLVGFKLPELSEAAEQDKGVSPELAPAAEEEESKSGLDVMPNISDILLRKLRVHKSLTGSAPPLTEKEVENVFVQLSLAFRNDSYTLESRINQAERERNLTEENTEKELENFKASITSSANIWYHCEHRETYQKLLEDIAVLHRLAARLSSRAEVVGAVRQEKRMSKATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSCG----PSEDGVPRTARSMSLTMGKNMPRRRVSVAVVPKFNALNLPGQAPSSSP--MP-SLPALSESSNGKSSISVSPALPALLENGKTNAEANCEVGA-PVPLPSCLEETSQETKAKAEEEAYSKGYQEGVKKTEELQDLKEEEEEEQKTESPEEPEEVEETQEDEKDQGSSKLEELVHFLQVMYPKLCQHWQVIWMMAAVMLVLSVVLGLYSSYNSCTEEADGPPGRSTCSAAQRDSWWSSGLQQELPAEQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6F6-9", "uniprot_id": "IRAG1_HUMAN", "id": "Q9Y6F6-9", "name": "Inositol 1,4,5-triphosphate receptor associated 1", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGMDLTCPFGISPACGAQASWSIFGADAAEVPGTRGHSQQEAAMPHIPEDEEPPGE-----PQAAQSPAGQGPPAAGVSCSPTPTIVLTGDATSPEGETDKNLANRVHSPHKRLSHRHLKVSTASLTSVDPAGHIIDLVNDQLPDISISEEDKKKNLALLEEAKLVSERFLTRRGRKSRSSPGDSPSAVSPNLSPSASPTSSRSNSLTVPTPPGLDVCSGPPSPLPGAPPQQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEKSKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEGSPLPRSPTQDAAGVGPPASQGRGPAGEPMGPEAGSKAELPPTVSRPPLLRGLSWDSGPEEPGPRLQKVLAKLPLAEEEKRFAGKAGGKLAKAPGLKDFQIQVQPVRMQKLTKLREEHILMRNQNLVGLKLPDLSEAAEQEKGLPSELSPAIEEEESKSGLDVMPNISDVLLRKLRVHRSLPGSAPPLTEKEVENVFVQLSLAFRNDSYTLESRINQAERERNLTEENTEKELENFKASITSSASLWHHCEHRETYQKLLEDIAVLHRLAARLSSRAEVVGAVRQEKRMSKATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSSRSCG----PSEDGVPRTARSMSLTLGKNMPRRRVSVAVVPKFNALNLPGQTPSSSS--IP-SLPALSESPNGKGSLPVTSALPALLENGKTNGDPDCEASA-PALTLSCLEELSQETKARMEEEAYSKGFQEGLKKTKELQDLKEEEEE-QKSESPEEPEEVEETEEEEKGPRSSKLEELVHFLQVMYPKLCQHWQVIWMMAAVMLVLTVVLGLYNSYNSCAEQADGPLGRSTCSAAQRDSWWSSGLQHEQPTEQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G1J8-1", "uniprot_id": "A0AC58G1J8_DANRE", "id": "A0AC58G1J8-1", "name": "", "aln": "MFHPCSRGWCSGFPHKSKDMRYRALAMASANSAGHQSHLDDVGPGISSFVSCDHDCHECSVPSLSTDSGTYSVDPCHLLENSEDFSSENRDLSDCADTNGLSEEELLNITFEACDTSGKGEVRVSTVIQYLQAMTLQSSGQDKITSLRHMLDPEKQDSPVSRDEFHATMREWIRKCCQDGASVDKNNTTESALRKSPIMGTERHLPLTEATYTDGDECSEPADLSGLVAELKHTQRRLKEQNSSLMRNVSQCEDTILTLSLEVSELHTKLASAQLYVVRARSLSEELDECRCALRESQERAARAHASNCTLIKDCEQLKALFRITEEKNEKLTLEKNLAEDRLNKLRKENSELRGELEESHLVLAVKDLELTKKCILLEKLRDTHFESHKVIEGLQSELMRLQEHSQQALFRLNKYHISSCGPHRTGLTNHQSLHQEIQEAQPDKVGNCASEKCLQDQQQHGSSRQELVTLLKELELLESPHGLHKAQHQTQEAHIAAAITWWRGQGKDGKINQTVQDPQEAVRDMQKRLQILEVERTRVILKDQGTSTSEDPLIQFRDVAMVTDSSEEHLAAGDMLKSLRKVEDMVTEVLRAAQVLMGCEKKMKERIKAISMRMERALSRGEATESQITLLENAQSLCKSQTIATGVLVDYSSPVVTTFSTPELVTQENTREHSISSQKGVSLLYTGATEDHSNKVNNTHHSTFKDPDPGSPSEFLLKRVSGVCFEPLFTGLPSVGVIIPPGHSSLYTQISLPEPSACEEPTPHNRQENVAGSDQPTSNDSFLSESGDTGSTLAANKETCTSLNKGDAGCPGTELQNSRRKTETSERCQNYSGRTEALKLLKQGKLSKFADDWDNQGFSSPREALVEDSGICQEERQESDCSGRSREESEHRGKSQARTKNSEAQEKHKTSDSDTLIRIQATGLADNLEGQQDPPPVCQFTHSRGEQTSLKSAPSFVTESVASFVFPHTRSRPPLTPAMPTLPEEEEDSPEELDSTSSSPSTYAPVESKMVSVNVSP-PAIVLQRQVIKQ--ESCPLEKARPHSPRPRLSRNSP--SSCPITTVDGDGHVIDLVKDQLPDLKLSEEDRQKNLELLEEAKKVSDRFLQRRGRRSTCSLTESPTALSPNPTPSSSPRPSRSSSLSSPSALGPEVSQTPPASPSLTQHLEVPSNHDQGDTSKPEQETFSRLVEWMPSDKRKVSSGTLTPRYTTAIPAREPSALQKDRPE-----HHGPAEKGKNSEHAGQKKEESPSRG------ITQPLATG-VAKPVPRPPTQQAPCTAEIKTIG----------------------AFPPLMRAVSWDIVGS------MNMRNAAPKGEDGPSFPDKQRESLFMSSGYKDFP--VPPGGVQKLSKLREEHKLVRNQSISSSKLPDLNEIAEQERGPPSPLISSPSEEETKEKPDAMPNISDVMLRKLKLHRGSTGCAPPLSEKEVENAFVQLSLAFRNDNYTLESRQKQAERERNLTEENLEKELEEFKVTLKSTVSLWQNVEQREFYQNLLETIAVLHRLTIRLSSRAEMVGAVRQEKRMNKATEVMMQYVENLKRTYEKDHAELMEFKKLANQNSNRCYGGSMDTGDEGVPRSSRSMSMQMGKALPRRRVSVAVVPKFNLLNIPGQTPAAGPNITPGALPVVCEANTIKNGSSSDPTQQDVPDKPSGNPLTEQESEATPTKVVCSPEKVTEEIKAKIEEEAYNKGYLEGLKKCKELQELKEEEEK------QKECDEEARANADKDRKTNSRFEEALEVLDRIFPKFFRRNRVLWIVLTLFFASFIIVNVINMLSSRYSDSGDTSAEKSAIPELRVNGRSV----------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ** :**:** . * ..:..: . .. ** *:*:* :. . *: * **: ***:. *:..:*:** **:****:*****:.:****::*** ****** **:*** ****:* .* ::*:*:*** :..:** .*** *:: .:. * : .. * :. . : : : . .. * :. . *.: .*:****.* *:** ... ::* : **:. : . * :. :*: :**. * * * *. .*:**...* : . : * : ***:*.:*** . :: * .*: *..* . ..* *** * * :***:****** *:***.: . ***:*.* ***::* .. * .: .***:*. *.******::****::*:. .*.****:******.***********.****** :************ *****:**.::.*:..:* : *:** **:*** *******: *******:**********.***********************************.*. * ..::****::****: :** :************** **:***:*::.. * :**.:.*: . :.. . .. : :: . * .: * * *. . *: ::* **: *****.**: **:** :***:******: :* :* .:: ::. .*::** :..*: ::**: :: :*:*:: ::::. :::.: . .* .::... ...:. . * . * ", "identical_positions": 347, "similar_positions": 251, "identity": "18.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120221-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35318-1", "uniprot_id": "ADML_HUMAN", "id": "P35318-1", "name": "Pro-adrenomedullin", "aln": "MKLVSVALMYLGSLAFLGADTARLDVASEFRKKWNKWALSRGKRELRMSSSYPTGLADVKAGPAQTLIRPQDMKGASRSPEDSSPDAARIRVKRYRQSMNNFQGLRSFGCRFGTCTVQKLAHQIYQFTDKDKDNVAPRSKISPQGYGRRRRRSLPEAGPGRTLVSSKPQAHGAPAPPSGSAPHFL-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97297-1", "uniprot_id": "ADML_MOUSE", "id": "P97297-1", "name": "Pro-adrenomedullin", "aln": "MKLVSITLMLLGSLAFLGADTAGPDTPSQFRKKWNKWALSRGKRELQASSSYPTGLADETTVPTQTLDPFLDEQNTTGPLQASNQSEAHIRVKRYRQSMN--QGSRSNGCRFGTCTFQKLAHQIYQLTDKDKDGMAPRNKISPQGYGRRRRRSLLEVLRSRTVESSQEQTHTAPGPWAHISRLFRI----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F5V1-1", "uniprot_id": "E7F5V1_DANRE", "id": "E7F5V1-1", "name": "Pro-adrenomedullin", "aln": "MQLILQSIFCCCLLAAVAPGVD----SAKHDLKRSVWLQ-RSKRDLSLP--------ALRALENRQFVRPDDVKDNLRP---HSSTDISIRAKRSKNSIN---QSRRSGCSLGTCTVHVLAHRLHDLNNKLKIGNAPVDKINPYGYGRRRRSVPEKVLRLRKDGSGMRMVWSSSNSQSWLHKLEALLRRT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:*: ::: ** :.... .::. * . * *.**:* . : : : * :. . . **.** ::*:* * ** :****.: ***:::::.:* * . ** .**.* ******* :. *. *. . :. . : ", "identical_positions": 43, "similar_positions": 51, "identity": "22.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120221-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43145-1", "uniprot_id": "ADML_RAT", "id": "P43145-1", "name": "Pro-adrenomedullin", "aln": "-MKLVSIALMLLGSLAVLGADTARLDTSSQFRKKWNKWALSRGKRELQASSSYPTGLVDEKTVPTQTLG-LQDKQSTSSTPQASTQSTAHIRVKRYRQSMN--QGSRSTGCRFGTCTMQKLAHQIYQFTDKDKDGMAPRNKISPQGYGRRRRRSLPEVLRARTVESSQEQTHSAPASPAHQDISRVSRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97297-1", "uniprot_id": "ADML_MOUSE", "id": "P97297-1", "name": "Pro-adrenomedullin", "aln": "-MKLVSITLMLLGSLAFLGADTAGPDTPSQFRKKWNKWALSRGKRELQASSSYPTGLADETTVPTQTLDPFLDEQNTTGPLQASNQSEAHIRVKRYRQSMN--QGSRSNGCRFGTCTFQKLAHQIYQLTDKDKDGMAPRNKISPQGYGRRRRRSLLEVLRSRTVESSQEQTHTAPGPWAH--ISRLFRI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P35318-1", "uniprot_id": "ADML_HUMAN", "id": "P35318-1", "name": "Pro-adrenomedullin", "aln": "-MKLVSVALMYLGSLAFLGADTARLDVASEFRKKWNKWALSRGKRELRMSSSYPTGLADVKAGPAQTLIRPQDMKGASRSPEDSSPDAARIRVKRYRQSMNNFQGLRSFGCRFGTCTVQKLAHQIYQFTDKDKDNVAPRSKISPQGYGRRRRRSLPEAGPGRTLVSSKPQAHGAPAPPSG---SAPHFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q9S2-1", "uniprot_id": "A0A8M9Q9S2_DANRE", "id": "A0A8M9Q9S2-1", "name": "", "aln": "MKSMLQKAFLWCMLTALLPSITSAKPLNTDGLRRFSVWLQSRVKRERSESD--MTDLLTQRNCDTESLVPQHRN----------------ARVKRTDPAYS-IKRVERAGCNLATCSVHELAHLLNIMHAKTNN--APTDKIGSNGYGRRRRRSLPSNQPALTFHEGRLKLAWVRSTHKGN--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::. ::: *.* : *: :: :::. * ** *** *. *.* :::* **** : . : . **.:.**:.::*** : : * :: ** .**..:********** . . *. ..: : . .. ", "identical_positions": 40, "similar_positions": 50, "identity": "21.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120222-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70265-1", "uniprot_id": "F262_MOUSE", "id": "P70265-1", "name": "6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------MSENSTFSTEDSCNSSYKPHASNL-------------RRAGKTCSWASYMTN---------------------------------------------------------------------SPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAV-KSYQSYDFFRHDNEEAMKIRKQCALVALEDVKAYFTEESGQIAVFDATNTTRERRDMILN-FAKQNAFKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMEDFLKRIECYKVTYQPLDPDNYDKDLSFIKVMNVGQRFLVNRVQDYIQSKIVYYLMNIHVHPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAHALKKFLEEQE-IQDLKVWTSQLKRTIQTAESLGVTYEQWKILNEIDAGVCEEMTYSEIEQRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIMELERQGNILVISHQAVMRCLLAYFLDKGADELPYLRCPLHIIFKLTPVAYGCKVETITLNVDAVDTHRDKPTH-NFPKSQTPVRMRRNSFTPLSSSNTIRRPRNYSVGSRPLKPLSP----LRALDMQEGADQPKTQVSIPVV--------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9JJH5-1", "uniprot_id": "F262_RAT", "id": "Q9JJH5-1", "name": "6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------MSENSTFSTEDSSSSSYKPHASNL-------------RRAGKKCSWASYMTN---------------------------------------------------------------------SPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAV-KSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYFTEESGQIAVFDATNTTRERRDMILN-FAKQNAFKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMEDFLKRIECYKVTYQPLDPDNYDKDLSFIKVMNVGQRFLVNRVQDYIQSKIVYYLMNIHVHPRTIYLCRHGESEFNLLGKIGGDSGLSLRGKQFAQALKKFLEEQE-IQDLKVWTSQLKRTIQTAESLGVTYEQWKILNEIDAGVCEEMTYSEIEQRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHIIFKLTPVAYGCKVETITLNVEAVDTHRDKPTH-NFPKSQTPVRMRRNSFTPLSSSNTIRRPRNYSVGSRPLKPLSP----LRALDMQEGADQPKTQVQQGSAQATEHLQKALEFANGHREVENVLAKHRRPSMASLTLLS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O60825-1", "uniprot_id": "F262_HUMAN", "id": "O60825-1", "name": "6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------MSG---ASSSEQNNNSYETKTPNL-------------RMSEKKCSWASYMTN---------------------------------------------------------------------SPTLIVMIGLPARGKTYVSKKLTRYLNWIGVPTKVFNLGVYRREAV-KSYKSYDFFRHDNEEAMKIRKQCALVALEDVKAYLTEENGQIAVFDATNTTRERRDMILN-FAEQNSFKVFFVESVCDDPDVIAANILEVKVSSPDYPERNRENVMEDFLKRIECYKVTYRPLDPDNYDKDLSFIKVINVGQRFLVNRVQDYIQSKIVYYLMNIHVQPRTIYLCRHGESEFNLLGKIGGDSGLSVRGKQFAQALRKFLEEQE-ITDLKVWTSQLKRTIQTAESLGVPYEQWKILNEIDAGVCEEMTYAEIEKRYPEEFALRDQEKYLYRYPGGESYQDLVQRLEPVIMELERQGNVLVISHQAVMRCLLAYFLDKGADELPYLRCPLHTIFKLTPVAYGCKVETIKLNVEAVNTHRDKPTN-NFPKNQTPVRMRRNSFTPLSSSNTIRRPRNYSVGSRPLKPLSP----LRAQDMQEGAD-------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B1V7-1", "uniprot_id": "A0A8M2B1V7_DANRE", "id": "A0A8M2B1V7-1", "name": "6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------MSA-WLQQEEAGPTSSAEAKKSEP-------------RGQEKKCSWASYMTN---------------------------------------------------------------------SPTVIVMIGLPARGKTYMSKKLTRYLNWIGVPTKVFNLGVYRREAV-KAYKSYDFFRHDNEEAMKIRKQCALVALQDVKIYLNEEGGQIAVFDATNTTRERRDLILD-FAQENAYKVFFVESVCDDPEVIAANILEVKVSSPDYPEAHRERVMDDFLKRIECYKVTYQPLDPDEYDKDLSFIKVINVGRRFLVNRVQDYIQSKIVYYLMNIHVHSHSIYLCRHGESEHNIQGRIGGDSELSSRGRQFASALHEFVEEHK-LSNLKVWTSQLRRTIQTAEELGVPYEQWKILNEIDAGVCEEMTYEMIQNTFPEEFALRDQDKYHYRYPGGESYQDLVQRLEPVIMELERQGNVLVICHQAVMRCLLAYFLDKSADDLAYLLCPLHTVMKLTPVAYGCKVEMFHLNVEAVNTHRDRPLQGKVRRDCAPLLLRRNSYTPLSSHDQVKRPRLYSAGNRPWLPLTPSPTTLHFPNTPDGALLLQQSQVSDSLNKLRNLTGTQCCPDTNPPSHWCSESPRNVTLSTDRA--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWH7-1", "uniprot_id": "Q9VWH7_DROME", "id": "Q9VWH7-1", "name": "", "aln": "MAQSTATAPLYAGYKPLISSVTTDTDPDPDMAPSLSAEGTADQPQKSQREGEVKGASSEAQRTKANPNQILSASNSSSIDEQDEDQVGTLPLPLLSINRRTPTLLPRPVPPSSTRFTSSYNDDLCTCSNCAYSSFSSSSSSASSTSSSSTSATAAGTALASAAASAVAKKLARSVTATSIMDMPYNTSPSLRVRTTSLNQLKKTADLAIENELHVCPSVMSEELRKLLPPTSETVMTKPFPIRGERTIADCTTPHVIAMVGLPARGKTFISKKLARYLNWIGISTRVFNLGEYRRHAT-TAYKSHEFFRADNEEAMAIRNRCANQALHDSCDWLLSGQGSIAVFDATNSTRDRRQLIHDIVVKQHGFRLFFVESICDDPQIIEQNILEVKVSSPDYLNMNTELVVRDFLQRIEHYEERYQPID-EVTESHLSFMKVYNAGKKVVVYNNEGHVESRIVYYLMNIHITPRTIYLTRHGESEYNLSGLIGGDSNLSARGHQYANALSTFIAQQQ-IDGLRVWTSWMKRAIQTVADVKAPQERWKALNEIDAGHCEEMTYEQIKEKFPEEFKARDVNKFAYRYPRGESYEDLVARLEPVIMELERQGNVLVVSHQAVLRCLFAYFLDKSADELPYLYVPLHTVIKLTPVAYGCKVEHIKLPIDAVDTHRPKPKI---PGDVSEPGLDGLSG-ELVAPDGVG--KVLIVGDDVAT----------ATNGNGGRVDVQAHQ-------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P32604-1", "uniprot_id": "F26_YEAST", "id": "P32604-1", "name": "Fructose-2,6-bisphosphatase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------MGYSTISNDND-----------------------------------------------------------------------------------------------------IKVCVIMVGLPARGKSFISQKIIRYLSWLSIKAKCFNVGNYRRDVSGNVPMDAEFFNFENTDNFKLRELAAQNAIKDIVNFFTKEDGSVAVFDATNSTRKRRKWLKD-ICEKNNIQPMFLESWSNDHELIINNAKDIGSTSPDYENSEPHVAEADFLERIRQYERFYEPLD-PQKDKDMTFIKLVNIIEEVVINKIRTYLESRIVFYVMNIRPKPKYIWLSRHGESIYNVEKKIGGDSSLSERGFQYAKKLEQLVKESAGEINLTVWTSTLKRTQQTANYLPYKKLQWKALDELDAGVCDGMTYEEIEKEYPEDFKARDNDKYEYRYRGGESYRDVVIRLEPVIMELERQENVLIITHQAVLRCIYAYFMNVPQEESPWMSIPLHTLIKLEPRAYGTKVTKIKANIPAVSTYKEKGTS-----QVGELSQSSTKLHQLLNDSPLEDKF------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . * . : *:*******:::*:*: ***.*:.: :: **:* ***.. . . :**. :* : : :*: .* *:.* :: . *.:*******:**.**. : : . ::: : :*:** .:* ::* * :: :**** : . . . ***:**. *: *.*:* :..::*:*: * ...:: . . :::*:**:*:***: .: *:* ***** .*: ***** ** ** *:* * :: : .* **** ::*: **. : :** *:*:*** *: *** *:: :**:* ** :*: *** ****.*:* ************ *:*:: ****:**: ***:: :: .:: *** ::** * *** ** : : **.*:: : . . * . : ", "identical_positions": 162, "similar_positions": 135, "identity": "20.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120228-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O55225-1", "uniprot_id": "OTOG_MOUSE", "id": "O55225-1", "name": "Otogelin", "aln": "--------------------MGARMPRRCLLLLS-------CFCLLRVESTAE------VQHQASALTWKISA--------------------------ELQQEPAPEPSHTYQEMSLAVEDVTTVMEGQEAEALAASAMSSWERRLHRAKCAPSYLFSCFNGGECVHPALCDCRRFNATGPRCQLVYNVGPERDSICRTWGQHHVETFDGLYYYFSGKGSYTLVGHHEPEGQS-FSIQVHNDPQCGSAHYTCPRSVSLFLSGEREICLAK-EVTHGGVRVQLPQVVGGVQLQQLAGYVIARHPSAFTLAWDGIS-AIYIKMSPEFLGWTHGLCGNNNADPQDDLVTSYGKVTDDVGEFVHSWQEQVPNSPPGPVTTSLPRPPCLQQSPASMQGVYERCEVLLRPPFDTCHAYVSPLPFAASCTSDLCQSGGDEATWCRALMEYARACAQAGRPLQGWRTQLSQCTVHCKEKAFIYNECIACCPASCQSRASCVDSEITCVDGCYCPNGLIFEDGGCMSPAECPCEFHGTLHPPGSVVTEDCNACTCTAGKWVCSSSVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKITPPYSDDAFEIRRLSSVFLRVRTNVGVRILYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACVPLVPGSLLDPCDVHLQAASYALQSCSVLTGELFAPCSAYLSPIPYFEQCRRDACRCGQPCLCATLAHYARLCRRHGLPVDFRAHLPACALSCEATKEYSPCVTLCAPTCQDLASPDVCGANGGGNFSREECVEGCTCPPDTFLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSELHPDPELSR----ERTCEQQLLNLSVPARGPCLSGCACPQGLLRHGDACFPPEECPCTWKGKEYFPGDQVVSSCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPYDFVGACKVHLVKSTSELSFSVMVEDVNCYGSGVICRKSISINVGSSLIIFDDDSGDPSPESFLDEKQAVHIWRAGFFTLVHFPREHITLLWDQRTTVHVQAGPQWQGQLVGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTPDPRDTCVLNPLREPFARKECGILLSEVFETCHPVVDVTWFYSNCLTDTCGCSRGGDCECFCASVAAYAHQCCQHGVVIDWRTPRICPYDCDFFNKALGKGPYQLSSVAAGGTLVATKAVDSDIALVRAEDLAPGDISSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHTTANGSIGLAKWQRDEAFHQHASFSLHRGTWQAGLVALESLAKPGSFLHSSGLELALRAYEHTEVFRGGALFRLLDAKPLGAAYPTCEWRYDACASPCFQTCRDPRATSCQDVPRVEGCVPVCPTPKVLDEVTQRCVYLEDCVEP------------------------------------APRGPTETLGNETLVPGQVPPTTSAEQ-QLPQGLPGASAYSPAPVPVAP----------------PTSAPNPPMAATEGQAPSPGSTQPTLQTPLGLTTSNFPAGHTEATAREEGAAS----LLTTSHPPGFSSSLPSSLQMPTSGIVS---GATETTKVTITFTGSPNTTVASRSPP-IPRFPLMTKAVT----------------------VPSHDSFPVKTTPL------QPSWLWSLSSRPMTSLG------------ATSWPPTSPGSH---LSTAVTKVANKTMTSLSVLAQS--------------TSSSSQPLAAV-TTAHRAPASPLVTKGLEV------VSATEKGEAGHSQLTELPVSPPPSPAPIDLP--HPAQHTTTAPGPSALSPGILAAGSPSTGAHR---------------------------------PGATALASLEPTRPPHLLSGLPLDTSLPLAKVGTSAPVATPGS------------KGYIPTPPPQHQATTLATAMTVSPLTQS-LSLTVPLMSAVEEQAHSPSPKPPQGTGMAPDQMLGATLPSFGASSVIAGVPPTVSAAPRKS--------TTQRAAILSKKVSPPTLISDSVQG----------------GFTELTPIVSHTVTPLATEAEGPRAGTVPLVPTTYSLSRVSARTASREGPLVLLPQLAEAYGTPAGLQPQED------LVRQATTEQSGRSAPAKS----------IAEESMEA-----EVNTSATCVP---IAEQDCVRHICLEGQLIRVNQTQHCPQGAVRPRCGVLGLAVRVGGDRCCPQWECACRCSIFPDLSFVTFDGSHAALFKEAIYVLSQSPDETISVHVLDCKSAN-LGHLNWPPFCLVILNVTHLAHHVSIDRFNRKVTVDSQVVWPPMSRYGFRIEDTGHMYIVRTPSHIQIQWLHSSGLMILEASKVS-KTQGHGLCGICDGDAANDLTLKDGSVLGEAEDPAPFLDSWQVPSSLTSEGQTRFRPDSCATADCSPCLRMVSNRTFSACHSFVSPESFCELWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWRGSDYCPFLCSSDSTYQACVAACEPPDTCQDGILGPLDPEQCQVLGEGCVCTEGTILHRRHSALCIPEDKCACTDSTGVPRALGETWNSSLSGCCQQQCQAPDTIIPVDLDCPGPRPESCPRFGEVILLQPTEDPCCLGSVCVCNQTLCEGLAPTCRPGHSLITHFQEDSCCPSYSCECDPGLCEAEQVPTCREDQILIEGRLGDSCCTSYFCGCGECSDPMPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGMGTSLVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRCTDVLDPLTNFYQINITSVLCDMHCEANQEYDHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASWIADCARHHCGSTPLGAVLVRSPISCPPFNETECAKVGGSVVPSLEGCCRAC------------------------KEDGRSCKKVTIRMTIRKNDCRSNTPVNLVSCDGRCPSASIYNHNINTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCACQWS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZCV6-1", "uniprot_id": "D3ZCV6_RAT", "id": "D3ZCV6-1", "name": "Otogelin", "aln": "--------------------MGARAPRLCLLLS--------CFCLLRVEPAAELEFKRTVQHQASALTWKAGE--------------------------ELQQEPAPEPSHSYQ-MPFAVEDVTTAMEGQDAEAFDAPAMSSWERRLHRAKCAPSYLFSCFNGGECVHPALCDCRRFNATGPRCQLVYNAGPERDSICRAWGQHHVETFDGLYYYFSGKGSYMLVGHHEPEGQS-FSIQVHNDPQCGPAHYTCPRSVSLFLSGEREICLAK-EVTHGGIRIQLPQVVAGVQLQQLAGYVIARYPSAFTLAWDGAS-AVYIKMSPEFVGWTHGLCGNNNADPQDDLVTSYGKLTDDIGEFVHSWQEQVPNSPPVPVMSSLPRPPCLQQSPASMQGVYERCEVLLRSPFDACHAYVSPLPFTASCTSDLCQSGGDEATWCRALTEYARACAQAGRPLQGWRTQLSQCTVRCKEKIFIYNECIACCPASCQSHASCVDSEIACVDGCYCPNGLIFEDGVCMSPAECPCEFHGTLHPPGSVVTEDCNTCTCTAGKWVCSSSVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKITPPYSDDAFEIQKLSSVFLRVRTNVGVRILYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACVPLAPGSLLDPCDVHLQAASYALQACSVLTGELFAPCSAYLSPIPYFEQCRRDACRCGQPCLCATLAHYARLCRRHGLPVDFRARLPACALSCEATKEYSPCVALCTQTCQDLASPDVCGANGGGNFSRDECVEGCTCPPDTFLDTQTDLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAATCPAGQVFVNCSELHPDPELSR----ERTCEQQLLNLSLPARGPCLSGCACPLGLLRHGDSCFPPEECPCTWKGKEYFPGDQVVSSCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSELSFSVMVEDVNCYSAGVICRKSISINVGSSLIIFDDDSGDPSPESFLDEKQAVHIWRAGFFTLVHFPREHITLLWDQRTTVHVQAGPQWQGQLVGLCGNFDLKTVNEMRTPENLELTNPQEFGSSWAAVECPDTPDPRDTCVLNPLREPFARKECGILLSEVFETCHPVVDVTWFYSNCLTDTCGCSRGGDCECFCASVAAYAHQCCQHGVVIDWRTPRICPYDCDFFNKALGKGPYQLSSVMAGSALVAMRAVDGDIALVRAEDLVPGDISSFLLTAALSKAKAHDPDVVSLEAADRPNFYLHVTANGSIRLAKWRRDEAFHQHASFSLHRGTWQAGLVALESLAKPGSFLQSSGLKLALRTYEHTEAFRGGALFRLLDAKPSGAAYPICEWHYDACASPCFQTCRDPQAASCQDVPRVEGCVPVCPTPKVLDEVTQRCVYLEDCVEP------------------------------------ALRGPKETLGNETLAPGQVLPTTSDKQ-QLPQEPPGASTHIPVLDPLAP----------------LTSAPNPPMAATEGPVASPGSTQPTLQTSLGLTTSNLPAGHTEATAREEGAAS----LLATSPPPGSSSSLPSSLQTPTSGILS---STTETTKVTLTFAGSPNTTVTSRSPP-VPRFPLMTKAVT----------------------VPSHDSFPVKTTPL------RPS--WSLSSRPTTSPG------------VTSWPPTSLGSH---LSTVVTNVTNKTETSLSVLAQS--------------TKSSSQPLS----TAYRAPASPLVTKGLEG------ASATEKGDAGHSQLTELPVSPPPSSAPIDLP--HPAQHTTTAPGSPALSPGILGAGSPSTGAHG---------------------------------LGTTALASLETTRPPHLLSGLPPDTSLPLAKVGTSAPVATPAS------------KGYVPTPPPQHWATTSATAMTVTPLTQTTLSLTAPLMSAVEEQAHSPSPTAPHITAMT---------PSFGASAGTAGVPPMVSVAPQKS--------TTQRAAILSKKVSPPTLISDSVQG----------------GFTELTPTVSHTVAPLVTEAEGPQAGTVPLVPTTHSLSRVSARTASREGPLVLLPQLAEAHGTPAGLQPQED------LVRQATTEQTGRSAPAQS----------IAEGSMEA-----EGNTSAICVP---IAEQDCVRHICLEGQLIRVNQTQHCPQGAVRPRCGVLGLAVRVGGDHCCPLWECACRCSIFPDLSFVTFDGSHAALFKEAIYILSQSPDEIISVHALDCKSAN-LGHLNWPPFCLVILNVTHLTHHISIDRFNRKVTVDSQVVWPPMSRYGFRIEDTGHMYIVQTPSHIQIQWLHSSGLMILEASKAS-KTQGHGLCGICDGDTANDLTLKDGSVLGEAEDPALFLDSWQVPSSLTSEGQTRFRPDSCSTADCSPCLRMVSNRTFSACHSFVSPESFCELWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWRGSDYCPFLCSSDSTYQACVAACEPPETCQDGVLGPLDPEQCQVLGEGCVCSEGTILHRRHSALCIPEDKCACTDSTGVPRALGETWNSSLSGCCQQQCQAPDTITPMDPDCPGPRPESCPRFGEVILLQPTEDPCCLGSVCVCNQTLCEGLAPTCRPGHRLIPHFQEDSCCPSYSCECDPGLCEAEQVPTCRQDQVLIEGRLGDSCCPSYFCGCGECPDAMPECQEGEVLTVHRNSTELCCPLYQCVCESFRCPQIQCGMGTSLVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRCTDVLDPLTNFYQINITSVLCDMHCEANQEYDHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASWIADCARHHCGSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC------------------------KEDGRSCKKVTIRMTIRKNDCRSNTPVNLVSCDGRCPSASIYNHNINTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCACQWS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZRI0-1", "uniprot_id": "OTOG_HUMAN", "id": "Q6ZRI0-1", "name": "Otogelin", "aln": "--------------------MGVLASALCWLLCVWLPWGEQAAESLRVQRLGERVVDSGRSGARGMRNVKGMR--------------------------NGPAQTRVSSSSSHQEATLAMGDKATVVGGQQAEAPDSVAMSSWERRLHRAKCAPSYLFSCFNGGECVHPAFCDCRRFNATGPRCQMVYNAGPERDSICRAWGQHHVETFDGLYYYLSGKGSYTLVGRHEPEGQS-FSIQVHNDPQCGSSPYTCSRAVSLFFVGEQEIHLAK-EVTHGGMRVQLPHVMGSARLQQLAGYVIVRHQSAFTLAWDGAS-AVYIKMSPELLGWTHGLCGNNNADPKDDLVTSSGKLTDDVVEFVHSWQEQAPNQPPGPTTSSLPRPPCLQQNPGTMQGVYEQCEALLRPPFDACHAYVSPLPFTASCTSDLCQSMGDVATWCRALAEYARACAQAGRPLQGWRTQLRQCTVHCKEKAFTYNECIACCPASCHPRASCVDSEIACVDGCYCPNGLIFEDGGCVAPAECPCEFHGTLYPPGSVVKEDCNTCTCTSGKWECSTAVCPAECSVTGDIHFTTFDGRRYTFPATCQYILAKSRSSGTFTVTLQNAPCGLNQDGACVQSVSVILHQDPRRQVTLTQAGDVLLFDQYKIIPPYTDDAFEIRRLSSVFLRVRTNVGVRVLYDREGLRLYLQVDQRWVEDTVGLCGTFNGNTQDDFLSPVGVPESTPQLFGNSWKTLSACSPLVSGSPLDPCDVHLQAASYSVQACSVLTGEMFAPCSAFLSPVPYFEQCRRDACRCGQPCLCATLAHYAHLCRRHGLPVDFRARLPACALSCEASKEYSPCVAPCGRTCQDLASPEACGVDGGDDLSRDECVEGCACPPDTYLDTQADLCVPRNQCSCHFQGVDYPPGDSDIPSLGHCHCKDGVMSCDSRAPAAACPAGQVFVNCSDLHTDLELSR----ERTCEQQLLNLSVSARGPCLSGCACPQGLLRHGDACFLPEECPCTWKGKEYFPGDQVMSPCHTCVCQRGSFQCTLHPCASTCTAYGDRHYRTFDGLPFDFVGACKVHLVKSTSDVSFSVIVENVNCYSSGMICRKFISINVGNSLIVFDDDSGNPSPESFLDDKQEVHTWRVGFFTLVHFPQEHITLLWDQRTTVHVQAGPQWQGQLAGLCGNFDLKTINEMRTPENLELTNPQEFGSSWAAVECPDTLDPRDMCVLNPLREPFAKKECSILLSEVFEICHPVVDVTWFYSNCLTDTCGCSQGGDCECFCASVSAYAHQCCQHGVAVDWRTPRLCPYDCDFFNKVLGKGPYQLSSLAAGGALVGMKAVGDDIVLVRTEDVAPADIVSFLLTAALYKAKAHDPDVVSLEAADRPNFFLHVTANGSLELAKWQGRDTFQQHASFLLHRGTRQAGLVALESLAKPSSFLYVSGAVLALRLYEHTEVFRRGTLFRLLDAKPSGAAYPICEWRYDACASPCFQTCRDPRAASCRDVPRVEGCVPVCPTPQVLDEVTQRCVYLEDCVEP------------------------------------AVWVPTEALGNETLPPSQGLPTPSDEEPQLSQESPRTPTHRPALTPAAP----------------LTTALNPPVTATEEPVVSPGPTQTTLQQPLELTASQLPAGPTESPASKGVTAS----LLAIPHTPE-SSSLPVALQTPTPGMVS---GAMETTRVTVIFAGSPNITVSSRSPP-APRFPLMTKAVT----------------------VRGHGSLPVRTTPP------QPSLTASPSSRPVASPG------------AISRSPTSSGSHKAVLTPAVTKVISRTGVPQPTQAQS--------------ASSPSTPLTVAGTAAEQVPVSPLATRSLEI------VLSTEKGEAGHSQPMGSPASPQPHPLPSAPP--RPAQHTTMATRSPALPPETPAAASLSTATDG---------------------------------LAATPFMSLESTRPSQLLSGLPPDTSLPLAKVGTSAPVATPGP------------KASVITTPLQPQATTLPAQT---------LSPVLPFTPAAMTQAHPPTHIAPPAAGTAPGLLLGATLPTSGVLPVAEGTASMVSVVPRKS--------TTGKVAILSKQVSLPTSMYGSAEG----------------GPTELTPATSHPLTPLVAEPEGAQAGTALPVPTSYALSRVSARTAPQDSMLVLLPQLAEAHGTSAGPHLAAE------PVDEATTEPSGRSAPALS----------IVEGLAEALATTTEANTSTTCVP---IAEQDCVRHICLEGQLIRVNQSQHCPQGAAPPRCGILGLAVRVGGDRCCPLWECACRCSIFPDLSFVTFDGSHVALFKEAIYILSQSPDEMLTVHVLDCKSAN-LGHLNWPPFCLVMLNMTHLAHQVTIDRFNRKVTVDLQPVWPPVSRYGFRIEDTGHMYMILTPSDIQIQWLHSSGLMIVEASKTS-KAQGHGLCGICDGDAANDLTLKDGSVVGGAEDPAPFLDSWQVPSSLTSVGQTRFRPDSCATTDCSPCLRMVSNRTFSACHRFVPPESFCELWIRDTKYVQQPCVALTVYVAMCHKFHVCIEWRRSDYCPFLCSSDSTYQACVTACEPPKTCQDGILGPLDPEHCQVLGEGCVCSEGTILHRRHSALCIPEAKCACTDSMGVPRALGETWNSSLSGCCQHQCQAPDTIVPVDLGCPSPRPESCLRFGEVALLLPTKDPCCLGTVCVCNQTLCEGLAPTCRPGHRLLTHFQEDSCCPSYSCECDPDLCEAELVPSCRQDQILITGRLGDSCCTSYFCACGDCPDSIPECQEGEALTVHRNTTELCCPLYQCVCENFRCPQVQCGLGTALVEVWSPDRCCPYKSCECDCDTIPVPRCHLWEKSQLDEEFMHSVENVCGCAKYECVKAPVCLSRELGVMQPGQTVVELSADGVCHTSRCTTVLDPLTNFYQINTTSVLCDIHCEANQEYEHPRDLAACCGSCRNVSCLFTFPNGTTSLFLPGASWIADCARHHCSSTPLGAVLVRSPISCPPLNETECAKVGGSVVPSLEGCCRTC------------------------KEDGRSCKKVTIRMTIRKNECRSSTPVNLVSCDGRCPSASIYNYNINTYARFCKCCREVGLQRRSVQLFCATNATWVPYTVQEPTDCACQWS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G5C7-1", "uniprot_id": "A0AC58G5C7_DANRE", "id": "A0AC58G5C7-1", "name": "", "aln": "MFISIYYANEQERGTGVISSSGDATNTQRREREERPVGREYASVEQRCETVRGEANSRSDSHESRMDPILTPGKKLFLLYLLFFILIYQAHITWGTESLNLTHQHDFENSSESSRIMLEKWDPAFQTEQRTLESNTSSAEQAEAQKPSTRRASGECASPCLNGGRCVHPDSCNCTLYQAAGTRCQTVPNLGFEREMTCRSWGQYNYETFDGLYYYFPGKCSYTLLRDCEDNARSSVHIQVHNDPECSSSPYSCTRSISLFLPWEGEIRLQHFSVTFKGQSVLLPHHIHDVELERISDYIVVSQPHVFTLAWQGLTSSVYIKMSPEFVGHTCGLCGNFNADTQDDLKTSYGVFTQDLAMFGNSWAEEEPELARCTVVPSLYPSPCATLDPHVLLKVEEVCSTLLREPFQSCHEFVSPYSYMASCSNDLCLSGPNGAVVCQVFTEYARACAHADHPLHDWRTHFPVCNVDCPDELLFR-ECITCCPMHCKIEQMCIDSKLQCLDGCYCPDDLIFEDGVCVKASDCPCEHHGMLYPSGHIIQEDCNNCTCFGGIWNCTEHNCPGECSVTGDMFFQSFDGRVYTFPATCQYVLAKSRNSGKFTVTIQNAPCGANLDGACIQSVNLVVNEDPRTEITMSHSGEVFLASQFRISLPYSDDMFQIQELSSMFVQVKLSQGLWLQYNWKEFRLYLQLEEQWRDNTLGLCGTFNGNIQDDFLAPSGMIESTPFLFGNAWRVSSACVPRPSLPQLDPCDTHQQAASYAVEKCDVLTQEVFSACHEYVSPVGFQLQCRADVCKCGALCLCSILAHYARTCRRHGVIIEFRSHLPECAVSCPSTMEYGVCVSACQRRCLFLSLPQPCG---------DECEEGCVCPEGTYFNMHTHTCVPRNECPCSFLGADYSPGDVIITSSGVQICQDGKLVSQTSIIETLCPAGQFYEDCGNRVDGPSASKGLACEQTCETYLLNLTCSTHEPCVPGCVCPAGLLKHGDECFKPRACPCLWKGKEYYPGDKVSSPCHQCVCQHGTFQCEFRPCPSMCTAYGDRHYRTFDGFLFDYIGVCKVYLVKSSLDAMLTVTAENVDCFESGVICRKSLHISVGRSFIVFDDDTGRPNPSSVID-RQRAYIWQAGYYTIVHLLGEDLTVLWDRKTTIHIQAGPRWQGRLTGLCGNFDQKTANEMRTPENIDSSTPQEFGNSWTAAECVNSPDIRHPCNLNPLREPFAKRQCGILLSEVFQVCHPVVDVTWFYMNCLVDTCGCNRGGDCECFCTSVAAYAHRCCQKGIPIDWRSPSICPYDCEYYNKALGKGPLKLLTYRERGTLLAANKTSGLVFPKRDLTSVDENLVLFMMTPGISKARPHDSSLVSFEAADRPNYFLKAEQGSQLRLGKWEDTPAFWDAATFVLHRDTWIPGFDSLESLARPGFFLHFMLSRLQLQKYSHSDRYRRATLFKLTGAIPHYPMGPRCQWRFESCVRPCFRTCSDPSGLSCTSILKIEGCLPQCPSHMVLDEVTHRCVSLEDCIRPPVVPPFTLPSTTISSTPFSEDYTSSIPAVSTALISTAVSESSATTTPTTHMPTTEKPTTSPIRPEVVEVITTLTTSSSSWSPLASTERTTKAPSITSSPTSSTTLYTSPVSISAPVSVTSTTSSPTESSTPFTRTTTIPSQPSSSPVLRSTSSSEQTRVSTLPVLPVSTSMGPTEATSPTVKVSSPLTSITETARVSEAITPTEKTTTPTVSSSGISQFPAESISMTKFTSLSTTTPVLEWRTSGTTAEMAPSTSLDTLKTPESTSETQKPSYTTTIPTSPTDTKASTTYITVKSTSSAFATPPATQTTLYTPSTTSEQPETSKTTVSFSTAAPTSLTTVSSQAPAFVPTKTTAKTTYQPTSVIYTYPDGPTTDRALQTDWRVIQTTSTQLELTETSQISVRTAETPLTTYTTMPPTWAPTEETTTLLTSQMSPTDKTTSRVPSTSTTLGYTESSWSLSSTTSLYTEKVSTSPIHPHYTTTVATTPALSEISSASPSILTSSVSQTTSISQTPTITTETAVTSEKPLLTSTAAEEEVVSTTQTSTTTHLTIHLDTETTKASLDTDRAVITTAATAQTPTLVHETSSTIPSTMAPRLTTRITPVLTSRVGVDTIRQTPQDVATTSISPPTRIETTMTTSTTVSTEKETSVSTTIPSTAAASSTLTTPIPEIPEFTSGFTEYTAVSGSTTTLPSFTGTTPTRTGTTTTPVASVLTQTTISTHLPTSSIVTTSSPITSSSTSTEHHLVDESPMVTTLPPTPDTAQTTRSTSVKTSLPYTIETEHWMTSQTQAVPKTTAHEPSRVCTAPYSEVVDECTKLICVSGQLLLFNKSQSCPYDPTPPNCGLLGFAVLVNGDKCCPRWDCPCRCSVFPDLNLITFDGKSVAIYKAALYVVTQLPNETVSILVQECSGPDDTLVWNFTNLCLAALNITHKSNEVLVNRLQRRLYVNSRYAKPRFKKYGFEILDTGNMYLIRSPAGLKIQWFHTTGMMVIEMDSYNNRLPTMGLCGSCDGNPLNDLTLSNGTVVPEQEDPAVFIDSWQIPNTTSYVSNSRRREVNCTTSDCSQCFNMLNNNTFTLCHAYVPPGVFCEMWVRDVEYVNNPCIALAAYAASCHKFNICMEWRSSDFCPFVCPGNLRYQACLPACTAP-SCPNQEF-EFVPEQCTGLSEGCVCPEGTLLHRPYSALCIPPSKCACTDSFGAPRALGEVWKASLDGCCMYKCEN-DSIVPVEYNCSNIPQPVCTRTGEITVNLADDSSCCPHKACVCNQSMCEAAPTGCKYGEKMVSYYRQDSCCPEYLCECDPDQCVLD-IPVCREDQTLIATRADGSCCLAHICMCDKCPEAVPVCQDGELLIVDTNSTERCCPAYHCLCEASRCLDITCPVGMAVVSARDPEECCPLQTCECACEKLLRPKCSLGQSMQLDRAFLSDPENICACKRFICVREAVCVDGERGVMRPGQTLVEHRDQGVCYATQCTHTLDSATGFYVLRSTGTNCTARCQPNQIYIPPKDPSSCCGTCKNISCLLRNENGSVAMYKPGRSWVSDCLRYDCSDTLAGPVLVTHPYSCPPFNETECMKIGGTIVSYMDGCCKTCAVNSLFPFSVSPLKPTVNTNCEQGKEDGKSCQKVTVRMTIRKNDCRSNRPVNIVSCDGKCPSASIYNYNINTYARFCKCCREMGLQRRSVQLYCSGNSTWVSYTIQEPTDCSCQWS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . * : . : : . * . : * : : *: : * .: :: :.: . .*:***.**** *:* ::*:*.*** * * * **: **:***:: *********:.** ** *: * :.:* . *******:*..: *:*.*::***: * ** * : .**. * : **: : ...*::::.*::. .*****:* : ::*******::* * ***** ***.:*** ** * .*:*: * :** *: *: . .. .** .** .* : * * *..*** **::** :*** .: ***:.*** * : *. *:.: *******:*.:**:.***:: *.* * :: : ***:*** *: . *:**:: *:******:.****** *: .::****.** *:*.* :: **** *** .* * *: **.*******:.* :**** *********:*****.**.****:****** * ****:***.:::::*** ::*::::*:*:* .*::* **:** *:*:.***:*::*: . *: : *: : :*****::::* ::*:********* *****:* *: **** ****:*:. *** * . . *****.* *****::: *.*** *:*:.* ::**: : *** *.*:** ***: *****: *****: ::**::** **:** :: **. **: * * *: *: ** :** ***.** .*::: ::. *****:*.* * *.**.*** *.* * *:** : .:: : *****.: :*.: . . *: *:*** ****: .:: **:.**.** ***:*** ** *. *** ******:***:* *.** ****:*:*** ::**.* **************: :*::*.***:****: : ::* .*:*:*: :*:**** : *.** *:*:****:* *.*.*.:* :* .: *:.*::*:**: *.:*:***::**:*:****:***:*.******* ** ********:: :.*****.**:*.** :: * *. * *********:::*.*******: *********** ***.*****.:********:**:****:***:*: :***:* :*****:::**.***** :* : .:*:. . ... : * . :: *::*..: **:.**..:**:*******::*:. ...: *.**. :* : *:* ***.* .*: :*****:*. ** * *: *.*:: :* .:**:* .* * . * *:*::::*. ***:** ** . ** .: ::***:* **: ******:*** ****:.* * .. : * * **.* . :: : . .: . * *. *: ..*:: : :. .:..* . . :: :*: :.:.. . ::* : : . * :* * ** : * . **::*: :: : : *..: *.. .:** : ::* : *: . .** :** : .: * : . . : .*:: : :. .:* .. .. * : :.:.: . . * .* . :.*: . :*: : ** .... . . * *::.** . .. : **.: :..: .:..: *. * *.:. **:. : . *: ...*. . *.. : : . . . . .* .: * . .: .. *:... .. ** .. .*:.* .* : .:. . * ** *. . . : . . .*.: *::.: * . :* .. : .*.: : : . * : **:.. : :* :.* *.. . ::*.: **:.***: .*::* ** ... *.**:**:** *.**:*** *:*.****:****.::****. .*::* *:*:::* *:* ::: . :*...: *:. :**. **:** ::.: ::*::*:: *: : . * ..:***.* ***:**:: :*: ::***:*::*:*::* .. . : **** ***:. *****.:*:*: **** *:****:*.: : .::* * .*:*:*** *:.*:.*.**: ** :*.* ***:*:**.:**::**:**:.*.* ****::*:*** **:***:*..: ****:.** .* :* : : : **:* *.*****.***:*** :****** ******* *.******.*::**.*** :*: *:* *:: .*.. * * **: : . ...** ..*****::**. .. *: *. ::.::::*****.* *****. * : :* **:** ** * ..*** :::* *..*.:.:* **:** * *. *:** *** *:*:** ** :: * :* ::*.. .*:.*** ::*** *:.: *:* * :. ***. *: . **:*.* :: **: .**:. * ***:****:** :***::::** .**. *.** :. *.. * :*:.** * *:* ::***:*:*:***: **:.::: ** **::** *:.*..* *.*** * ****:***** *:**::*. ::***::* ****:**:***:*******:***. ***:*****:********:**************:*********:*: *:***.**:******:****", "identical_positions": 1196, "similar_positions": 895, "identity": "37.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120228-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5PQS4-1", "uniprot_id": "GULP1_RAT", "id": "Q5PQS4-1", "name": "PTB domain-containing engulfment adapter protein 1", "aln": "-------------------------------------MN-------------------------RAFSRKKDKTWMHMPEALSKHYVPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEG---QKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNK-----------------------HLCFVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKD--VETRKQIAGMQKRIQDLETENMELKNKVQDLENRLR-------------------------------------------TTQVSSTP------------------------------AGGVTVTSPS-------------------TDIFDMIPFSPI--------SHPSPTSAGNGTQLPPIPSRSSEIKRDLFGAEP--FDPFNCGAGDFPP-------DIQSKLDEMQ-----EGFKMG--------LTLEGTVFCLDPLDSRC-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8K2A1-1", "uniprot_id": "GULP1_MOUSE", "id": "Q8K2A1-1", "name": "PTB domain-containing engulfment adapter protein 1", "aln": "-------------------------------------MN-------------------------RAFSRKKDKTWMHTPEALSKHYIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEG---QKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNK-----------------------HLCFVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKD--VETRKQIAGMQKRIQDLETENMELKNKVQDLESRLR-------------------------------------------TTQVSTSP------------------------------AHGVTVMSPS-------------------TDIFDMIPFSPI--------SHQSPTSARNGTQLPPIPSRSAETKRDLFGAEP--FDPFNCGSGDFPP-------DIQSKLDEMQ-----EGFKMG--------LTLEGTVFCLDPLDSRC-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBP9-1", "uniprot_id": "GULP1_HUMAN", "id": "Q9UBP9-1", "name": "PTB domain-containing engulfment adapter protein 1", "aln": "-------------------------------------MN-------------------------RAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEG---QKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNK-----------------------HLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKD--VETRKQIAGLQKRIQDLETENMELKNKVQDLENQLR-------------------------------------------ITQVSAPP------------------------------AGSMTPKSPS-------------------TDIFDMIPFSPI--------SHQSSMPTRNGTQPPPVPSRSTEIKRDLFGAEP--FDPFNCGAADFPP-------DIQSKLDEMQ-----EGFKMG--------LTLEGTVFCLDPLDSRC-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PMJ1-1", "uniprot_id": "A0A8M9PMJ1_DANRE", "id": "A0A8M9PMJ1-1", "name": "PTB domain-containing engulfment adapter protein 1", "aln": "MRLDGLRVEGNNYKINLPCGLTLESALSLQALLKLCRMN-------------------------RAFNRRKDKPSMHTPEALVKSHVVYNAKFLGITEVDQPKGTDMVRVAVRKLKFQRHIKKSEG---HKTPKVELQISIYGVKILDPKTKEMLHNCQLHRMSFCADDKTDKRIFTFICTEPETKK-----------------------HLCYVFDSEKCAEEITLAIGQAFDLAYKKFLESGGKD--VETRKQIGNLQKRIQDLEMENSKLKKKLKELEDQLTDPRC-------------SPRASTLSWCGEDVTSLSSLEISSVTLTPVSSPDSSQSASLLTPPPAKPTHSQPKSDYIVPRPRTGSIQARAPS-------------------TDIFDMVPFTPE--------SPITRRLNFNGFSSPYLTPKDTDI--DLFGAEP--FDPFICGPTVFTP-------DMQSKLDEMQRQRWFEGFQMG--------LTLEGTVFSLEPVDSRC-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7JUY7-1", "uniprot_id": "CED6_DROME", "id": "Q7JUY7-1", "name": "PTB domain-containing adapter protein ced-6", "aln": "MPYQPANSGGTSGGSKAAAKMAQLKFWNKQNSSKQQQQDKDKDAADGGNNTSGGGTGSNSNGDAKSEAKNGKRNWLHTPEQLISGHAVYLVKFFGNLSVDQPKGIEVVKEAIRKLQFAQQMKKAETGTQEKFKKLEITISIKGVAIQEPRTHKILHQFPLYNISYCADEKGVKKFFSFIAKTVKTQDGSDPTSNGHANGNGDGSAKVEESHECFVFISNKLASDITLTIGQAFDLAYRKYMDSTEKTNLSKAQQQINHLQQTVNVYKERLREVSAKLPKAELDALLFNLGIKDILEAPTTEPQNGIEVASEALSNGKLDDDKLLIDTNSTTASTHSASPSSFLPIVPPRNNLSSQISIGGKSNSQKMDELLLNSDSDSDFDPRADETQEIGGTGRSAISNMFGFEPANSFGQHLFSNNNDHKLQNNNSSLLITSNNNSINSSGFSSELNITPPLLAPPPKIAAPRRLNSVTTGNGLNGNTDLFGSDPFELNNGPNIFKQNQLNLDDFSLESLDPLRK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :: :. .: :* ** * . . * .**:* .*:**** ::*: *:***:* :::**:* .* *:*: *** ** * :*:*::: *: *:.:*:***:* *::*:**.. :::. * *:** *:* *.:***:*********:*:::* * ::::** :*: :: : . ::. *: . * * .*: : : * : * :*. * * * . *. . :.... . . *.:* *: . . :.. . *: : *::. *: *.*:.:*. ", "identical_positions": 89, "similar_positions": 107, "identity": "17.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120229-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TSF1-1", "uniprot_id": "DSG1B_MOUSE", "id": "Q7TSF1-1", "name": "Desmoglein-1-beta", "aln": "--MDWHSFRIAALLLTS----LVVLEVNSEFQIQVRDHNAKNG------------------------TIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQ--PVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFIINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGA-DGMSAESECSITILDVNDNIPYLEQSSYDIEIEENALHSQLVQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAMKNLQLSIGVRNVAEFHQSIISQYRLTATMVTVTVLNVIEGSVFRPGSKTFVVDSRMEA----NHRVGEFVATDLDTGRAS-----TNVRYEMGNNPENLLVVDSRTGIITLRNRVTMEQYQRLNGEYKGTVLSIDDSL-QRTCTGTIVIELSGT-GWVPGSDGGGSSSGSGGNRDPVTN---GYQGTS-TVGPQRVTGSGGVTSSGGGSGVNNTPGRQNPLDEPEPEPFD------------------------------------------------------------ITEDNVHFGPAGIGLLIMGFLVLGLVPFLLICCDCG--GAPGGGAG-FEPVPECSDGAIHTWAIEGPQPEPHDGITTICVPQMPPGN-------------ANVIEYIDNSGVYTNEYC--GREMQDLGGGERTTGFELMDG-----------------------VKTS---AAPEICQ---EYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEG---VGSPAGSVGCCSFIGEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDSSWPPQ------------------STEPMC-PQSTEPLGSGYPPISPHFGTTTVISENAYPSGPGVQHPLPIPDPLGYGNVTVRESYATSG-TLKPSVHFHDN--QQASNVVVTERVVGPVPG----------------------ADLHGMLEIP-DLRDGTNVIVTER--VIAPGSSLPTSLTIPNPRET-SNVVVTERVIQPTSGMIGNLSMTPELSSAQNVIVTERVVSGAGMSGIAGTAGLGGVGGIGSSGLVSTTMGAAGTGLN-------------MGGTATIGHMRSSSDHHFSQTIG-SASPNMARSRITKYSTVQYSK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q61495-1", "uniprot_id": "DSG1A_MOUSE", "id": "Q61495-1", "name": "Desmoglein-1-alpha", "aln": "--MDWHSFRIAALLLTS----LVVLEVNSEFQIQVRDHNAKNG------------------------TIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQ--PVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFIINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGA-DGMSAESECSITILDVNDNIPYLEQSSYDITIEENALHSQLVQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAMKNLQLSIGVRNVAEFHQSIISQYRLTATMVTVTVLNVIEGSVFRPGSKTFVVDSRMEA----NHRVGEFVATDLDTGRAS-----TNVRYEMGNNPENLLVVDSRTGIITLRNRVTMEQYQRLNGEYKGTVLSIDDSL-QRTCTGTIVIELSGT-GWVTGSESGGSSSGSGDDRDRVTN---GYQGTSSTENPQRVTG------SWGGSGIDGTRPNTNPFQGDPDETLET----------------------------------------------------------PLYGDNVHFGPAGIGLLIMGFLVLGLVPFLLICCDCG--GAPGGGAG-FEPVPECSDGAIHTWAVEGPQPEPHEGITTICVPQMPPGN-------------ANVIEYIDNSGVYTNEYC--GREMQDLGGGERTTGFELMDG-----------------------VKTS---AAPEICQ---EYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEG---VGSPAGSVGCCSFIGEDLDESFLDTLGPKFKKLADISLGKEIDSYPDSDPSWPPQ------------------STEPMC-PQHTEPLGSGHPPISPHFGTTTVISENAYHSGPGVQHPVPIPDPLGYGNVTVRESYTTSG-TLKPSVHFHDN--QQASNVVVTERVVGPISG----------------------ADLHGMLEIP-DLRGGANVIVTER--VIAPGSSLPTSLTIPNPQET-SNVVVTERVIQPTSGMIGNLSMTPELSSAHNVIVTERVVSGAGMSEIAGTAGLGGVGGIGSSGLVSTTMGASGTGLN-------------MGGTATIGHMRSSSDHHFSQTVG-SASPSMARSRITKYNTVQYSK----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7TSF0-1", "uniprot_id": "DSG1C_MOUSE", "id": "Q7TSF0-1", "name": "Desmoglein-1-gamma", "aln": "--MDWHSFRIAALLLTS----LVVLEVNSEFQIQVRDHNAKNG------------------------TIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQ--PVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGA-DGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEA----NHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDS--GIITLRNRVTMEQYERLNKRYEGTVLSIHDSL-QRTCTGTIIMVLCG--FWTT-------------TEHPTTS---TEKPVTLSITPN--------------------------------------------------------------------------------------------------VDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCG--GAPGGGAG-FEPVPECSDGAIHTWAVEGPQP---GGITTICVPQMPPGN-------------ANVIEYIDNSGVYTNEYC--GREMQDLGGGERTTGFELMDG-----------------------VKTS---AAPEICQ---EYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEG---VGSPAGSVGCCSFI-EDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQ------------------STEPIC-PQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSG-TLKPSVHFHDN--QQASNVVVTERVVGPISG----------------------ADLHGMLEIP-ALRDGTNVIVTER--VIAPGSSLPNSLTIPNPRET-SNVVVTERVIQPTSGMIGNLSIPP-------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZM39-1", "uniprot_id": "D3ZM39_RAT", "id": "D3ZM39-1", "name": "", "aln": "--MDWHSFRRAALLLAF----LVVLEVNSEFQIQVRDHNAKNG------------------------TIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQ--PVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSLIAFKIVRQEPSEAPMFIINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGA-DGMSAECECSISILDVNDNIPYLDQSSYDIKIEENALHSNLQQFRVIDLDEEYSDNWKAVIFFVTGNEGNWFEIEMNERTNVGTLKVVKPLDYEAMQKLQLSIGVRNVAEFHQSILSQYTLTVTMITVKVLNVVEGSVFRPGSKTFVVHSRMDA----NYRVGEFTATDLDTGMTS-----TNVRYVMGNNPEGLLVVDSKTGIITLRNRVTMEQYQRLNGRYEGTMLSIDDSL-QRTCTGTIIIELDGT-GWETGGGGGGGGGGGGDGGGGGDG---GGGGGSGSGGDGGGGDGGG-QVTNGYKDTSTEEPQRTTLTRDIDNTDTY----------------------------------------------------------QADEDNVHLGPAGIGLLIMGFLVLGLVPFLLICCDCG--GAPGGGAG-FEPVPECSDGAIHTWAVEGPQPEPHDGITTICVPQMPPGN-------------ANIIECIDNSGVYTNEYC--GREMQDLGGGERTTGFELVDG-----------------------VKTS---AAPEICQ---EYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEG---AGSPTGSVGCCSFIGEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQ------------------STEPIC-PQRTEPLASGHPPISPHFGTTTVISENTYPSGPGIQHPMQIPDPLGYGNVTVRESYTTSG-TLKPSVHFHDN--RQASNVVVTERVVGPISG----------------------ADLHGMLEIP-DLRDGSNVIVTER--VIAPGSSLPTSLTIPNPLET-SNVVVTERVIQPTSGMIGNLSMPPELSSAHNVIVTERVVSGAGVSGVTGTAGIGGVGGIG--TMSAGGVGDGGTGMS-------------MGGTATIGHMRSSSDHHFSQAVG-SASPSMARSRITKYSTVQYTK----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q02413-1", "uniprot_id": "DSG1_HUMAN", "id": "Q02413-1", "name": "Desmoglein-1", "aln": "--MDWSFFRVVAMLFIF----LVVVEVNSEFRIQVRDYNTKNG------------------------TIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQ--QVTYRISGVGIDQPPYGIFVINQKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANTLVMILNATDADEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGSDRDGGA-DGMSAECECNIKILDVNDNIPYMEQSSYTIEIQENTLNSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAEFHHSIMSQYKLKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGS----NDKVGDFVATDLDTGRPS-----TTVRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYNMLGGKYQGTILSIDDNL-QRTCTGTININIQSF-GNDDRTN------TEPNTKITTNT---GRQESTSSTNYD----------------TSTTSTDSSQVYSSEPGNGAK----------------------------------------------------------DLLSDNVHFGPAGIGLLIMGFLVLGLVPFLMICCDCG--GAPRSAAG-FEPVPECSDGAIHSWAVEGPQPEPRD--ITTVIPQIPPDN-------------ANIIECIDNSGVYTNEYG--GREMQDLGGGERMTGFELTEG-----------------------VKTS---GMPEICQ---EYSGTLRRNSMRECREGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEG---VGSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLADISLGKE--SYPDLDPSWPPQ------------------STEPVCLPQETEPVVSGHPPISPHFGTTTVISESTYPSGPGVLHPKPILDPLGYGNVTVTESYTTSD-TLKPSVHVHDN--RPASNVVVTERVVGPISG----------------------ADLHGMLEMP-DLRDGSNVIVTER--VIAPSSSLPTSLTIHHPRES-SNVVVTERVIQPTSGMIGSLSMHPELANAHNVIVTERVVSGAGVTGISGTTGIS--GGIGSSGLVGTSMGAGSGALSGAGISGGGIGLSSLGGTASIGHMRSSSDHHFNQTIG-SASPSTARSRITKYSTVQYSK----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6W3B0-1", "uniprot_id": "DSG4_RAT", "id": "Q6W3B0-1", "name": "Desmoglein-4", "aln": "--MDWLLFRNICLLILF----MVVLGVNSEFIVEVKELDIENG------------------------TTTWQTVRRQKREWIKFAAACREGEDNSKRNPIARIRSDCEVSQ--RITYRISGAGIDRPPYGVFTINPRTGEINITSVVDREITPLFLIHCRALNSRGEDLERPLELRVKVMDVNDNPPVFTQNVYTANIEENSDANALVVKLSATDADEDNHLNSKIAYKIISQEPAGAPMFMVNRYTGEVRTMSNFLDREQHSMYNLLVRGSDRDGAT-DGLSSECDCRIKILDVNDNFPILEKTSYSASIEENCLSSELIRLQAIDLDEEGTDNWLAQYSILSGNDGNWFEIQTDPKTNEGILKLVKMLDYEQEPNIYLSIGVRNQAEFHHSVASQFQMHSTPVRIQVINVREGPTFRPSSMTFSLRGGMRGDSLMNYVLGTYTAIDMDTGSPA-----TNVRYVIGHDAGSWLKVDSRTGEIQFSREFDTKSKYITDGMYAAEILAIDDGS-GRTATGTICIEVPDANDYCPVIYAESRSVCTHASSVRIYV---NDHSFGAPFTFCVVDESPDTADIWDIRSINGTSAILMTEQTLSPGPYQIPILVKDSHNRACELPQTVLLDACLCDDYHVCLHSSTTGIYTGDTIWVTDDMG-TVTDDGLRQSNVGLGPAGIGMIILGLLLLFLSPLLLLMCCCKRRQPEGLGTR-FAPVPEGGEGVMQPWRIEGAHPEDRD-VSNICVPMTAS----------------NTQDRIDSSEIYTNTYAGGGTVEGGVSGVELNTGVGTAAG-----------------------IAAG---GATGTLR---KRSSTIG--TLREYQDTGMNMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDHEG---TGSPVGSIGCCSWIVDDLDESYMETLDPKFRTLAEICLDTEIEPFPSHQACIPIS------------------TDLPLLGPNYFVNESSGMTLSEAEFQAEMAAAS----------------EPMIHGDIIVTETYTATDPCVQPTTIVFDS--QLPPNVVVTETVMAPVY------------------------DVQGNICVPAEIANTHNVYYAER--VVAS----------PGVPDM-GNGNIGDTCIGPV--MSGGILVGPEIQVTQ----------------------------------------------------------------------MMSPDIHISQTTR-STSPMTSQHRVTRYSNIHYSRQ---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TMD7-1", "uniprot_id": "DSG4_MOUSE", "id": "Q7TMD7-1", "name": "Desmoglein-4", "aln": "--MDWLLFRNICLLILF----MVVLGVNSEFIVEVKELDIENG------------------------TTTWQTVRRQKREWIKFAAACREGEDNSKRNPIARIRSDCEVSQ--RITYRISGAGIDRPPYGVFTINPRTGEINITSVVDREITPLFLIHCRALNSRGEDLERPLELRVKVMDVNDNPPVFTQNVYTANIEENSDANALVVKLSATDADEDNHLNSKIAYKIISQEPAGAPMFMVNRYTGEVRTMSNFLDREQHSMYNLLVRGSDRDGAT-DGLSSECDCRIKILDVNDNFPILEKTSYSASIEENCLSSELIRLQAIDLDEEGTDNWLAQYSILSGNDGNWFEIQTDPKTNEGILKVVKMLDYEQEPNIYLSIGVRNQAEFHHSVASQFQMHSTPVRIQVVNVREGPTFSPSSMTFSLRGGMRGASLMNYVLGTYTAIDMDTGNPA-----TNVRYVIGHDAGSWLKVDSRTGEIQFSREFDMKSKYITDGIYAAQILAIDDGS-GRTATGTICIEIPDANDYCPVIYAESRSVCTHASSVRIYV---NDHSFGSPFTFCVVDESPDIANIWDIRSINGTSAILMTEQTLSPGPYQIPILVKDSHNRACELPQTVLLDACFCDDHHVCLHSSTTGIYTGDITWVTDDMYGTVTDDGVRQSNVGLGPAGIGMIILGLLLLLLSPLLLLMCCCKRRQPEGLGTR-FAPVPEGGEGVMQPWRIEGAHPEDRD-VSNICVPMTAS----------------NTQDRIDSSEIYTNTYAGGGTVEGGVSGVELNTGVGTATG-----------------------MVAA---GATGTLR---KRSSTIG--TLREYQDTGMNMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDHEG---AGSPVGSIGCCSWIVDDLDESYIETLDPKFRTLAEICLDTEIEPFPSHQACIPIS------------------TDLPLLGPNYFVNESSGMTLSEAEFQAEMAAAS----------------EPMIHGDIIVTETYTTSDPCVQPTTIVFDS--QIPPNVVVTETVMAPVY------------------------DVQGNICVPAEIANTHNVYYAER--VVAS----------PGIPDM-GNSNISDACIGPV--MSGGILVGPEIQVTQ----------------------------------------------------------------------MMSPDIHISQTTG-STSPMTSQHRVTRYSNMHYSRQ---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86SJ6-1", "uniprot_id": "DSG4_HUMAN", "id": "Q86SJ6-1", "name": "Desmoglein-4", "aln": "--MDWLFFRNICLLIIL----MVVMEVNSEFIVEVKEFDIENG------------------------TTKWQTVRRQKREWIKFAAACREGEDNSKRNPIAKIRSDCESNQ--KITYRISGVGIDRPPYGVFTINPRTGEINITSVVDREITPLFLIYCRALNSRGEDLERPLELRVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLCATDADEENHLNSKIAYKIVSQEPSGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRGSDRDGAA-DGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEGTDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHYSVASQFQMHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAIDLDTGNPA-----TDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAIDDGS-GKTATGTICIEVPDINDYCPNIFPERRTICIDSPSVLISV---NEHSYGSPFTFCVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYACDCDDNHMCLDSGAAGIYTED---ITGDTYGPVTEDQAGVSNVGLGPAGIGMMVLGILLLILAPLLLLLCCCKQRQPEGLGTR-FAPVPEGGEGVMQSWRIEGAHPEDRD-VSNICAPMTAS----------------NTQDRMDSSEIYTNTYAAGGTVEGGVSGVELNTGMGTAVG-----------------------LMAAGAAGASGAAR---KRSSTMG--TLRDYADADINMAFLDSYFSEKAYAYADEDEGRPANDCLLIYDHEG---VGSPVGSIGCCSWIVDDLDESCMETLDPKFRTLAEICLNTEIEPFPSHQACIPIS------------------TDLPLLGPNYFVNESSGLTPSEVEFQEEMAAS-----------------EPVVHGDIIVTETYGNADPCVQPTTIIFDP--QLAPNVVVTEAVMAPVY------------------------DIQGNICVPAELADYNNVIYAER--VLAS----------PGVPDM-SNSSTTEGCMGPV--MSGNILVGPEIQVMQ----------------------------------------------------------------------MMSPDLPIGQTVG-STSPMTSRHRVTRYSNIHYTQQ---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZL74-1", "uniprot_id": "D3ZL74_RAT", "id": "D3ZL74-1", "name": "", "aln": "-------------------------MVYGELHIESGGQHREDR------------------------MALQLTKRRYKREWVKFAKPCREREDNSKRNPIAKITSDFQKNQ--KITYRISGVGIDQPPFGIFVVDPNNGDINITAIVDREETPSFLITCRALNALGQDVERPLILTVKILDVNDNAPIFSQTIFKGEIEENSASNSLVMILNATDADEPNHMNSKIAFKIVSQEPAGMSMFLISRNTGEVRTLTSSLDREQVGSYHLIVSGADNDG---TGLSTQCECSIKIKDVNDNFPVLTDSQYSARIEENTLNSELLRFQVTDWDEEYTDNWLAVYFFTSGNEGNWFEIETDPRTNEGILKLVKVLDYEQMQSMQFSIAVRNKAEFHQSVISQYQVQSTPVTIQVINVQEGISFRPPSRTFTVQRGVSINKLAGYILGTYQATDEDTGKAA-----SSVRYVLGRNDGGFLVIDSKTAEIKFVKNINRDSTFIVNKTISAEVLAIDENT-GKTSTGTVYVEVPSFNENCPSVVLEKREICTSSPSVTLSVRTLDRAKYTGPYTVSLEEQPLKLPVVWTITTLNATSALLQAQQHISPGVYNVPVIVKDNQDGQCDTLESLTLTVCQCDDRSMCRAPGPSR---------------EPFIRE--ESTWRLGPAAIGLILLGLLMLLLAPLLLLTCDCGSGPIGGAGTGGFVPVPDGSEGTIHQWGIEGAQPEDKE-ITNICVPPVTS----------------NGADFMESSEVCTNTYAG-GTLVEGASGMEMTTKLGGAT--------------------GSGAAVALG-LGHSGTMR---TRHSTGG--TLKDYAA-PVNMTFLGSYFSQKSSAYAEEEDDREVNDCLLIYDDEGEDAAPRSP-ALSSCSFMADDLDDSFLDSLGPKFKKLAEICLGVDDEAKQVKPGPKDSS------------------SGADACARPTEALQAGSNRYQTLPGGLEVTQSGSN-------------RYQTLPGGLEVTQSGSNRYQTLPGGLEVTQSGSKVCHVLPGNQDTSVLSSS----------------------GSVHPAIAIPDPLQLG-NYLLTET--YTTSGSFVQPTTATFDPHVT-QNVTVTERVICPLPSASGSIVAPTELRGSYS---------------------------------------------------------------------MLYTKEACSHL----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O35902-1", "uniprot_id": "DSG3_MOUSE", "id": "O35902-1", "name": "Desmoglein-3", "aln": "--MTCLFPRALGSLALL----MVVLLVQGELHVKPGGQHREDG------------------------TALQLAKRRYKREWVKFAKPCREREDNSRRNPIAKITSDFQKNQ--KITYRISGVGIDQPPFGIFVVDPNNGDINITAIVDREETPSFLITCRALNALGQDVERPLILTVKILDVNDNPPIFSQTIFKGEIEENSASNSLVMILNATDADEPNHMNSKIAFKIVSQEPAGMSMFLISRNTGEVRTLTSSLDREQISSYHLVVSGADNDG---TGLSTQCECSIKIKDVNDNFPVLRESQYSARIEENTLNAELLRFQVTDWDEEYTDNWLAVYFFTSGNEGNWFEIETDPRTNEGILKVVKALDYEQVQSMQFSIAVRNKAEFHQSVISQYRVQSTPVTIQVIDVREGISFRPPSKTFTVQRGVSTNKLVGYILGTYQATDEDTGKAA-----SSVRYVLGRNDGGLLVIDSKTAQIKFVKNIDRDSTFIVNKTISAEVLAIDENT-GKTSTGTIYVEVPSFNENCPSVVLEKKDICTSSPSVTLSVRTLDRGKYTGPYTVSLEEQPLKLPVMWTITTLNATSALLQAQQQVSPGVYNVPVIVKDNQDGLCDTPESLTLTVCQCDDRSMCRAPIPSR---------------EPNTYG--ESSWRLGPAAIGLILLGLLMLLLAPLLLLTCDCGSGPIGGAATGGFIPVPDGSEGTIHQWGIEGAQPEDKE-ITNICVPPVTT----------------NGADFMESSEVCTNTYAG-GTMVEGASGMEMITKLGGAT--------------------GATAALGPCSLGYSGTMR---TRHSTGG--TLKDYAA-PVNMTFLGSYFSQKSLAYAEEEDEREVNDCLLIYDDEGEDAAPHSP-TLSSCSIFGDDLDDNFLDSLGPKFKKLAEICLGIDDEAKQAKPGPKDSG------------------SGADTCAR-----------------------------------------------SMEVPQSGSNRYQTLPGSLEVTQTGSKICHTLSGNQETSVMSTS----------------------GSVHPAVAIPDPLQLG-NYLLTET--YSTSGSFAQPTTVTFDPHVT-QNVTVTERVICPLPSASSSIVAPTELRGSYN---------------------------------------------------------------------MLYTKETCSHL----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P32926-1", "uniprot_id": "DSG3_HUMAN", "id": "P32926-1", "name": "Desmoglein-3", "aln": "--MMGLFPRTTGALAIF----VVVILVHGELRIETKGQYDEEE------------------------MTMQQAKRRQKREWVKFAKPCREGEDNSKRNPIAKITSDYQATQ--KITYRISGVGIDQPPFGIFVVDKNTGDINITAIVDREETPSFLITCRALNAQGLDVEKPLILTVKILDINDNPPVFSQQIFMGEIEENSASNSLVMILNATDADEPNHLNSKIAFKIVSQEPAGTPMFLLSRNTGEVRTLTNSLDREQASSYRLVVSGADKDG---EGLSTQCECNIKVKDVNDNFPMFRDSQYSARIEENILSSELLRFQVTDLDEEYTDNWLAVYFFTSGNEGNWFEIQTDPRTNEGILKVVKALDYEQLQSVKLSIAVKNKAEFHQSVISRYRVQSTPVTIQVINVREGIAFRPASKTFTVQKGISSKKLVDYILGTYQAIDEDTNKAA-----SNVKYVMGRNDGGYLMIDSKTAEIKFVKNMNRDSTFIVNKTITAEVLAIDEYT-GKTSTGTVYVRVPDFNDNCPTAVLEKDAVCSSSPSVVVSARTLNN-RYTGPYTFALEDQPVKLPAVWSITTLNATSALLRAQEQIPPGVYHISLVLTDSQNNRCEMPRSLTLEVCQCDNRGICGTSYPTT---------------SPGTRYGRPHSGRLGPAAIGLLLLGLLLLLLAPLLLLTCDCGAGSTGG-VTGGFIPVPDGSEGTIHQWGIEGAHPEDKE-ITNICVPPVTA----------------NGADFMESSEVCTNTYAR-GTAVEGTSGMEMTTKLGAATESGGAAGFATGTVSGAASGFGAATGVGICSSGQSGTMR---TRHSTGG--TNKDYADGAISMNFLDSYFSQKAFACAEEDDGQEANDCLLIYDNEGADATGSPVGSVGCCSFIADDLDDSFLDSLGPKFKKLAEISLGVDGEGKEVQPPSKDSG------------------YGIESCGHP----------------------------------------------------------------IEVQQTGFVKCQTLSGSQGASALSTS----------------------GSVQPAVSIPDPLQHG-NYLVTET--YSASGSLVQPSTAGFDPLLT-QNVIVTERVICPISSVPGNLAGPTQLRGSHT---------------------------------------------------------------------MLCTEDPCSRLI---------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1LYX9-1", "uniprot_id": "F1LYX9_RAT", "id": "F1LYX9-1", "name": "", "aln": "--MARSPSGRCTLLLLLQLLAVVCLDFGDGLHLEVFSTRGEDRL-----------------------FTKRTHLVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGIKITYKYTGKGITEPPFGIFVFDRNTGDLNITSILDREETPFFLLTGYALDSRGNNLEKPLELRIKVLDINDNEPVFTQEVFVGSIEELSAAHTLVMKITATDADDPQTLNSKISYRIVSQEPANTPVFYLNKDTGEIYTTSFALDREEHSSYSLTVEARDGNGQITDKPVQQAQVQIRILDVNDNIPVVEYGTYEGVVEENQVNVEVMRIKVTDADEVGSDNWLANFTFASGNEGGYFHIETDTQTNEGIVTLVKELDYEEMKKLDLSILVTNKAAFHKSVVSKYKATPIPITVKVKNVVEGIHFKSSTVTFRASEAMDRSSL-SRSIGKFQVFDEDTGKAA------DVTYVKVQDTDNWVSVDSETSEIKLVKIPDFESRHVQNGTYTVKVVAISKGHPQKTVTGTILINVEDVNDNCPVLVDSVRSVCADAPYVNVTAEDLDGPRNSGPFTFSIIDQPPGTAQKWKITHQESTSVLLQPSER-KLGRSEIPFLISDSQGFSCLERQVLQLTVCECLEGG-------------------------GCVAALYDNYVGLGPAAIALMILALLLLLLVPLLLLMCHCG------EGAKGFAPIP-GTIEMLHPWNNEGAPPEDKVVPSLLVTDHVENSGVRGGGGGGGGGVGGVKLKEGVS---SSASITKGQHELIEVDGRWEEHRSLLTSG-------------------LTHHVATAGSIAANDTTIRTTRATGASRDMSGARG-AVAMNEELLRSYFTEKAASYAGEDDFHLAKDCLLVYSQED---TDSLRGSVGCCSFIEGELDDLFLDDLGPKFKTLAEVCLGRKIDMDVDIEQRQKPVRETSVNAAPGSHYTQVTASSESTYSSNSGFQAPKPLHGAHTEKVTQEVVTESSVSSRQSQKVVPP-PNPVASGNIIVTETSYAAGSAVPPSTVILAP--RQPQSLIVTERVYAPASTLVDQHYANEENVLVTERVIQPNGGIPKPLEVTQHLNDAQYVMVRERESILAPSSGVQPTLAMPSVAAGGQNVTVTERVLTPASTLQSSYQIPSEASIKARKTVLSS-----------------------------------------------------------VGGMGPLPNLDLEESGPPNSTVTTSSTRVTKHSTVQHSYS---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O55111-1", "uniprot_id": "DSG2_MOUSE", "id": "O55111-1", "name": "Desmoglein-2", "aln": "--MARSPGDRCALLLLVQLLAVVCLDFGNGLHLEVFSPRNEGKP-----------------------FPKHTHLVRQKRAWITAPVALREGEDLSRKNPIAKIHSDLAEEKGIKITYKYTGKGITEPPFGIFVFDRNTGELNITSILDREETPYFLLTGYALDSRGNNLEKPLELRIKVLDINDNEPVFTQEVFVGSIEELSAAHTLVMKITATDADDPETLNAKVSYRIVSQEPANSHMFYLNKDTGEIYTTSFTLDREEHSSYSLTVEARDGNGQITDKPVQQAQVQIRILDVNDNIPVVENKMYEGTVEENQVNVEVMRIKVTDADEVGSDNWLANFTFASGNEGGYFHIETDTQTNEGIVTLVKEVDYEEMKKLDLSIIVTNKAAFHKSILSKYKATPIPITVKVKNVVEGIHFKSSVVSFRASEAMDRSSL-SRSIGNFQVFDEDTGQAA------KVTYVKVQDTDNWVSVDSVTSEIKLVKIPDFESRYVQNGTYTAKVVAISKEHPQKTITGTIVITVEDVNDNCPVLVDSVRSVCEDEPYVNVTAEDLDGAQNSAPFSFSIIDQPPGTAQKWKITHQESTSVLLQQSER-KRGRSEIPFLISDSQGFSCPERQVLQLTVCECLKGG-------------------------GCVAAQYDNYVGLGPAAIALMILALLLLLLVPLLLLICHCG------GGAKGFTPIP-GTIEMLHPWNNEGAPPEDKVVPSLLVADHAESSAVRGG-------VGGAMLKEGMMKGSSSASVTKGQHELSEVDGRWEEHRSLLTAG-------------------ATHHVRTAGTIAANEAVR--TRATGSSRDMSGARG-AVAVNEEFLRSYFTEKAASYNGEDDLHMAKDCLLVYSQED---TASLRGSVGCCSFIEGELDDLFLDDLGLKFKTLAEVCLGRKIDLDVDIEQRQKPVREASVSAASGSHYEQAVTSSESAYSSNTGFPAPKPLHEVHTEKVTQEIVTESSVSSRQSQKVVPP-PDPVASGNIIVTETSYAKGSAVPPSTVLLAP--RQPQSLIVTERVYAPTSTLVDQHYANEEKVLVTERVIQPNGGIPKPLEVTQHLKDAQYVMVRERESILAPSSGVQPTLAMPSVAAGGQNVTVTERILTPASTLQSSYQIPSETSITARNTVLSS-----------------------------------------------------------VGSIGPLPNLDLEESDRPNSTITTSSTRVTKHSTMQHSYS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14126-1", "uniprot_id": "DSG2_HUMAN", "id": "Q14126-1", "name": "Desmoglein-2", "aln": "--MARSPGRAYALLLLL-----ICFNVGSGLHLQVLSTRNENKL-----------------------LPKHPHLVRQKRAWITAPVALREGEDLSKKNPIAKIHSDLAEERGLKITYKYTGKGITEPPFGIFVFNKDTGELNVTSILDREETPFFLLTGYALDARGNNVEKPLELRIKVLDINDNEPVFTQDVFVGSVEELSAAHTLVMKINATDADEPNTLNSKISYRIVSLEPAYPPVFYLNKDTGEIYTTSVTLDREEHSSYTLTVEARDGNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEGMVEENQVNVEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKNLDFSVIVANKAAFHKSIRSKYKPTPIPIKVKVKNVKEGIHFKSSVISIYVSESMDRSSK-GQIIGNFQAFDEDTGLPA------HARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRYVQNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTLIEPVQTICHDAEYVNVTAEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQESTSVLLQQSEK-KLGRSEIQFLISDNQGFSCPEKQVLTLTVCECLHGS-------------------------GCREAQHDSYVGLGPAAIALMILAFLLLLLVPLLLLMCHCG------KGAKGFTPIP-GTIEMLHPWNNEGAPPEDKVVPSFLPVDQGGSLVGRNG--------VGGMAKEATMKGSSSASIVKGQHEMSEMDGRWEEHRSLLSGR-------------------ATQFTGATGAIMTTETTK-TARATGASRDMAGAQAAAVALNEEFLRNYFTDKAASYTEEDENHTAKDCLLVYSQEE---TESLNASIGCCSFIEGELDDRFLDDLGLKFKTLAEVCLGQKIDINKEIEQRQKPATETSMNTASHSLCEQTMVNSENTYSSGSSFPVPKSLQEANAEKVTQEIVTERSVSSRQAQKVATPLPDPMASRNVIATETSYVTGSTMPPTTVILGP--SQPQSLIVTERVYAPASTLVDQPYANEGTVVVTERVIQPHGGGSNPLEGTQHLQDVPYVMVRERESFLAPSSGVQPTLAMPNIAVG-QNVTVTERVLAPASTLQSSYQIPTENSMTARNTTVSG-----------------------------------------------------------AGVPGPLPDFGLEESGHSNSTITTSSTRVTKHSTVQHSYS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BIB6-1", "uniprot_id": "DSG2L_DANRE", "id": "A0A8M2BIB6-1", "name": "Desmoglein-2-like protein", "aln": "MGVASPLPNTYSAFFGDAAPPTVAAAVADRPLVSPCQSSASNGRRMAKICSISLLVVLSLSILNASASGEQQKKVRQKREWIIPPRKLRENVNYMYLDYIAKIRSDEETRT--SIRYSLKGAGADQPPRDLFTVGSTDGKVKINGLLDREKTPVYYLQGVAKFLNGSNAEKDVDLRVVVLDENDCPPVFN--LTIGAVSELSARDTLVMSITATDADEEGTLHTKIAYSIVEQS--HAEMFYINRETGGIYVMHNTLDREKIDSYTLTVKGTDMNGAP-GGNSGTGKVVINILDVNDNVPTLEKNIYECRVEENTRFVEVVRIQAIDADLIYTDNWLAVFTLVSGNEAGYFSITTDKKTNEGILMLNKELDYEELKEIRLQVSVSNKAHYHSSVVITG-SKTYTIQVSVINQPEAPRFKPAVKVITISE-ESTTVILNKVITNYAAIDSDTMLIA-----TNVRYAKGQDVDNWLIIDEKTADIRLNKIPDYESVFLKNYTYYAHILCITNETPAKTATGTIAIQVKDFNDHCPVLIHQSQKLCYEEHVVFVTAE--DKDHFPNAHPFGFKVNTKHTKESWSVEHFNDTAAIFRSQETLWPGVYHLSVDVWDQQGKVCG-AQLLRVEVCMCGAEKVCLP---------------------------VTVVSRFGGSGVLLMLLGLLLLLLIPLLLLFCLCG----AAGAAGDFKAIPFDAKEHLIAYNTEGQGEDKGMALLHMSKDENTR------------------TNVGTVGGAQKQSDGKDGAVTAGGSHWSTFYHYDQFNN----------------------NAYHHHRDRTDGDFMYAQRKDEHSRFENYNAFDGLALSDAFLGNYYSQKSSHVAQKQALG---DNLKVYEYEGQ--ESRAGSFEDICSLMHEEEDLAFLDNLDMKFKTLAEICSGSTIQRESINVSSKKTE-------------------SKDLSVQETSNILQSQEKKSSTILAGSVNQSS----------------------NMQQTSQEKKTSTIIAGSINQSSSLQHASTGVYLQEQVMLPNTT-----------------------LLVQQPALYYAPAAPVYVVEPHPTVLVASGQVLGHQENQKRPKNAKHETHYQSLVYVEQQQPLRESQGSISGAVHMVN----------------------------------------------------------------TEIMQSTEGHGVRREIRPARRVMMEEVREREVDSLHLRVPMSL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . :. . * ** *: . ** : : **:* ** : * .* * .** .:* .. *.:::..::*** ** : : * * : *. : * : ::* ** *:*. . :.* * .:**: : *****: ::: ::: *: . :* :.: ** : . ****: . * * * . * :* . * : *****.* . ::** :: .::. * * : ** * : :**:..:* * : :** * : : * :*** .: : : * * * :* *: : : * : :. * . . : : . * :* : * .: . : :*. . : : . .. . ::.* . :* ***: : : . . :* :.: ::::.:*:* * *:*:: * * : * .:* : : ** . . . :. :: .*: :*: :: * * :*. * . ** : : * :: *. **:.**::. . : : . . :. : . ", "identical_positions": 121, "similar_positions": 180, "identity": "9.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120313-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LX00-1", "uniprot_id": "A0ABK0LX00_RAT", "id": "A0ABK0LX00-1", "name": "", "aln": "MGTEYNCCKVSLASSACLLLRFLWSLTFAYCTVLYLGTNKPSPGEHIELSEGKLSVSTAGAKHTSFLHEVPNHRRKTKAKAPLPPAEMKGMDVSSAEDPVESIPVSTEQHDNMIDKDIELSVVLPGDVLKSTTVHGSKPMMDLLVFLCAQYHLNPSSHTINLLSAEENLIKFKPNTPIGMLEVEKVILKPKSLDKK--KPTPIIPEKTVRVVINFKKTQKTIVRVSPHSPLQDLAPIICSKCEFDPLHTVLLKDYQAQEPLDLTKSLNDLGLRELYAMDISRAPSVTAFSKSSF-----QESCQISHNPDIVKEKENKGIFSFFQRSKKKREQ---TASAPATPLVSKHRPSFTR--SNTISKPYISNTLPSDAPKKRRAPLPPMPTSQGAAQG----QERRASCVERSTSVDDTDKSSSEGFMVRTGSLQLSGSTSVGTSSLKRTKRKAPAPPSKPSLTETDEGSSAAAHGLPLEDGIVPDSISEVSSPEGMSSP--------------------------------------AGVSSDYSLEEIDEKEELMEASKDQAG--SVKSPTIASASTDMIITAENDPDSALSISDGETSPGSKGNTPEGRNPEGQGPHHPVECLIGNENNVSDSIKDLKTLSPNQESVIQNEVVVCAT-STDYVKNRPREMEATIEG--EAQKKVGDVEAERLSGSPAGRMDDVQSSRENHLTASPGPDQKSNQPRVEKTKMQDAAIQATPACSTFDGNHEAHNSPDLRVDETAQTLGSSTSTQHSSASFQDSVNASREVRSQGTS-TYVQDRLPVKEAACTYGNNDALSPIDGSGKNPAASSLKNFPLYRQDNHPKPKPSNEITREYIPKIGMTTYKIVPPKSLEVVKDWDSEAAGKKDNQKTLAVAQKHAIETMTETAVQAEALVTSKNSQQPQPDRTPKPSSGTEHPLHRTVSSPVGTEMNPPK-PPRMTTDTGTIPFAPNLEDINNILESKFRSRASNPQAKPSSFFLQMQKRASGHYVTSAAAKSVHTAPGPTPKEPTIKEVQRDPQLPPEQCLSPLSERTHSAPLPNISKADDNRIQKPAETSPPPVAPKPMALPAETSPPAVAPKPMAFPAETSLPPVSPKPMALPTEASSSPISPKPMAPPAEASIPPVVPKPMAPPAEASPLPVAPKPMAFPAETSLPPVAPKPMALPTEASPPPVAPKPLALPGSQGASLNLKTLKTFGAPRPYNSSAPSPFALAVVKRSQSFSKASPESPSEDSSAQPPAAIQDGKTQTVNQPTVGSQHDGVDKQNKPVQNEHSSQRLTPADGPSSFTLQRQSSLNFQSSDPEHIRQSLLTAIRSGEAAAKLKRVTVPSNRISVNGKSGLSQPMSIDAQDSC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UMF0-1", "uniprot_id": "COBL1_MOUSE", "id": "Q3UMF0-1", "name": "Cordon-bleu protein-like 1", "aln": "-----------MDRSVPDPLPRSAPRTPAMQPAGSAGKRR-----FMKMFHAHSKNDFVRIKNHKFLPLHICQSRKTKGKAPLPPAETKGTDVSSAEDPVESTAVVTEQQDNMIDKDIELSVVLPGDILKSTTVHGSKPMMDLLVFLCAQYHLNPSSHTIDLLSAEENLIKFKPNTPIGMLDVEKVILKPKSLDKK--KPTPIIPEKTVRVVINFKKTQKTIVRVSPHAPLQDLAPIICSKCEFDPLHTVLLKDYQAQEPLDLTKSLNDLGLRELYAMDISR------------------ESCQISHNPDIVKEKENKGIFSFFQRSKKKREQ---TASAPATPLVSKHRPSFTR--SNTISKPYISNTLPSDAPKKRRAPLPPMPTSQGAAQG----QERRASCVERSTSVDDTDKSSSEAIMVRTGSLQLS-STSIGTSSLKRTKRKAPAPPSKTPLAQTDERNSAMAHGLPLEDGIAPDSMLELSSPEGMSTPEGSLGPGFLSQEQCAVPKPPDEISEGPGTPETAVASLTSGVSSDYSLEEIDEKEELSEASKDPAGSISVKSPDIASASTDMRITVEKDPDSALGISDGETSPSSKGKTQEGRSTEGQGPYHPVVGHIGNEDRVSDSIKDMKTLGPNQESVVQNEIMVCAT-STDYVKNRPGKMETTIEGEGEALKKASDMETDRLSGSPACRMDNVKSSRENHLTASPGPDQKLNQPGVEKTKMQDAAIQATPARGTFDGNHEVSNSSDPRADETVQTSDGSISAQHSSASLQDSVNASREFRSQGTS-TYVQDRLPEKEPACTYGNNVPLSPVDGSNKNPAASYLKNFPLYRQDSNPKPKPSNEITREYIPKIGMTTYKIVPPKSLEMAKDWESEAMGRKDDQKMLPVGQRHTIENMTETSMQTEVPATSKSSQQPQPDLKPKPSSGTERHLHRTLSSPTGTETNPPK-APRVTTDTGTIPFAPNLEDINNILESKFRSRASNPQAKPSSFFLQMQKRASGHYVTSAAAKSVHTAPGPAPKEPTIKEVQRDPQLSPEQHPSSLSERTHSAPLPNISKADDDIIQKPAETSPPPVAPKPMTLRAETSPPPVFPKPMTLPAETSPPPVFPKPMTLP------------------------------------------------AETSLPLVFPKPMTLRAETSPPPVAAKPVALPGSQGTSLNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSFSKACPESASEGSSALPPAATQDEKTHTVNKPTVGSQHGDGDKQNNPVQNEHSSQVLTPADGPS-FTLKRQSSLTFQSSDPEHVRQSLLTAIRSGEAAAKLKRVTVPSNTISVNGKSGLSQSMSIDAQDSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q53SF7-4", "uniprot_id": "COBL1_HUMAN", "id": "Q53SF7-4", "name": "Cordon-bleu protein-like 1", "aln": "------------------------------------------------------------MDGRTPRPQDAPARRKPKAKAPLPPAETKYTDVSSAADSVESTAFIMEQKENMIDKDVELSVVLPGDIIKSTTVHGSKPMMDLLIFLCAQYHLNPSSYTIDLLSAEQNHIKFKPNTPIGMLEVEKVILKPKMLDKK--KPTPIIPEKTVRVVINFKKTQKTIVRVSPHASLQELAPIICSKCEFDPLHTLLLKDYQSQEPLDLTKSLNDLGLRELYAMDVNR------------------ESCQISQNLDIMKEKENKGFFSFFQRSKKKRDQ---TASAPATPLVNKHRPTFTR--SNTISKPYISNTLPSDAPKKRRAPLPPMPASQSVPQDLAHIQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLS-SMSAGNSSLRRTKRKAPSPPSKIPPHQSDENS--RVTALQPVDGVPPDSASEANSPEELSSP--------------------------------------AGISSDYSLEEIDEKEELSEVPKVEAENISPKSQDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEEKQETKSTDGQEP-HSVVYDTSNGKKVVDSIRNLKSLGPNQENVVQNEIIVYPENTEDNMKNGVKKTEINVEG--VAKNNNIDMEVERPSNSEAHETDTAISYKENHLAASSVPDQKLNQPSAEKT--KDAAIQTTPSCNSFDGKHQDHNLSDSKVEECVQTSNNNISTQHSCLSSQDSVNTSREFRSQGTLIIHSEDPLTVKDPICAHGNDDLLPPVDRIDKNSTASYLKNYPLYRQDYNPKPKPSNEITREYIPKIGMTTYKIVPPKSLEISKDWQSETIEYKDDQDMHALGKKHTHENVKETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAPKMTRDTGTAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTDDDVIG---------------------------------------------------------------------------------------------------------------QAPAEASPPPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSFSKERTESPSASALVQPPANTEEGKTHSVNKFVDIPQLGVSDKENNSAHNEQNSQIPTPTDGPS-FTVMRQSSLTFQSSDPEQMRQSLLTAIRSGEAAAKLKRVTIPSNTISVNGRSRLSHSMSPDAQDGH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6Z2T6-1", "uniprot_id": "A0A8M6Z2T6_DANRE", "id": "A0A8M6Z2T6-1", "name": "", "aln": "-----------MTADSRAKLQRRSSARDCRAAAG---------------------------MDGNAHNRPPDRRRSTKSKAPPPPVLTGLDAPLLSHKLQAFPHPAMEQTESLLEQELTLTVILPGGAEKITTVHGSKPMMDLLVMLCAQHHLNPSGHTLELITTNRNHVKFKPNALIGALEADKILLKPKGMEDKSKKTGPHMPEATVRLVINYRKTQKTILRVSPRVPLRELLPAICQKCEFDPQTTLLSPSVQSEDTLDLSGSLNDFGLREVYARDTRVISPVSPISPVSLPPSPTRSEIFYHGKEKSLREKDNKRRFSLFRRGSKKQSEQSMTVSAPASPVHRKQRPVSMSSFSTHVPLSYDCNTMPSDTPKKRRAPLPPSMMSQSMPSD-----------LSQTQTTVHPDGNQNLSSLSRASSTESSFKKSS-------TKRKAPPPP-----------------VMISTDTTHQDTTDSSMTESAVTSP----------------------------------------------LEEIKEQEEMSVGAGVNVEDETLED----NSSLNMSANISLDSGRAGTATPSQDSVTLESGTPRDDPVCDLSTDAEVAEGTVNGEMKADQTRSSHITSEDKDPGKTEQLIQPSE-------SGPVLEEVTVSN--------TSLPQRSECGIQTSQTDLQVQCFDSDTAISS-PESSCSIYAEAQTSKTIPNTSSLTHTETQTQVQSSNEPSSLCTEFSTSTIGLKKDMATSTDELQPSIQQSKDLTSTSKPASVSYVTDAEPKPKPSNEHTRGYIPKVGMTTYTIVPQKSLEKLHSLEIEMTLEP--KVDCKPNVSNGTVTLNGHQNAFAQTNQCTSPPATNSTNLSTNLSTKPTSLSANTTYSSTKPTSSSTSPTYLSTNPTNWSTNPINSSTSPTYLSTNPSNSSTNPTNSSTKQTNSSTNPTNSSSVDERIDSVSLKDKKVPPATRPKPASFRVPQHKRMSGDYVSSAAVRRASIGSSSSSSSCCSSPAARPKESLSSPQSDVFPAMEIFPPPPPPVQWEEEQSQSTSAKSLPQNEE----------------------------------------------------------------------------------------------IDAALPEAPKIPPSSFLSRQKSLPTNPAPSLSLEKLRSFAAPKPYSPSSPSRFAQAVSSAVK-----------RSQSLSHHAPVQETRTHTLTKQRPIRESPEPPTSTVADNGDREPETQTADTDPVMGTCKIGN--TQASPGSEASSQEVSDVFHSAEE----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *..*.*** **. : . ** :.:::::: *:*:***. * *************::****:*****.:*::*::::.* :*****: ** *:.:*::**** ::.* *. * :** ***:***::******:****: .*::* * **.****** *:* . *:::.***: ****:****:** * .. : . ::**:** **:*:*..**:.: *.****:*: *:** *. :. .* .**:***:********** **. ... : :: :. ..* . . *:.* : * . * ******.** : * *: . : . :::* ****.*:**: . . : :. * :: . . *.. * .: * . . . . * * . *. :. : . ::: :::: . . * .:.. .: .. : . * . :.. : *. *:.. . :* . .: . : :. : .. .: ..* . . . * . * *:: *::. * .. . .. : : * . . .. . *: : . . :* :: : . * .* : : : .. : .: . . . . :: :. * . .. * .. :. :.* .: .* : ..: * .: . . :..::: : :. * :. .. .:.**:** : :** **.**:***.: . ....:... . . * .. . :. * * : ::: .: .*... .: ::* . .: .*:.*::*.**:**..*.** ** ** . : . * :: :*:::.: : ... . :.::..: *. .* * . . *...* *.: .::*.* ", "identical_positions": 234, "similar_positions": 350, "identity": "17.07%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120314-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZD32-1", "uniprot_id": "CHD5_RAT", "id": "D3ZD32-1", "name": "ATP-dependent chromatin remodeler CHD5", "aln": "MRGPLGTEEELPRLFAEEMENEE-------------------------EMSEEEDGGLEG------FEDFFPAEP-VSLPKKK-PKKLKESKS-KGKRKKKE----GSNDELSENEEDLEEKSESEGSDYSPTKKKKKKLKEKKEKK---AKRKKRDEDEEDNEDGGLKEPKSSGQLMAEWGLDDVDYLFSEDDYHTLTNYKAFSQFLRPLIAKKNPKIPMSKMMTVLGAKWREFSANNPFK----GSSAAAAAAAVAAAVETVTIAPPLAIS-PQQVPQPLPVRKAKTKEGKGPGVRKKNKGAKDSKKKGRGKRVAGLKFRFGGIS-KRKKGSSSEEDEPED-SDLDN----------------ASIHSSSVRSECSAALGK---------------------KNKRR-RKKKRIDDGDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELEKAPEGKWSCPHCEKEGIQWEPKDDDEEEEEGGCEEEEDDHMEFCRVCKDGGELLCCDACPSSYHLHCLNPPLPEIPNGEWLCPRCTCPPLKGKVQRILHWRWTEPPAPFMVGLPGPEVEPGMPPPRPLEGIPEREFFVKWAGLSYWHCSWVKELQLELYHTVMYRNYQRKNDMDEPPPFDYGSGDEDGKSE-KRKNKDPL-------YAKMEERFYRYGIKPEWMMVHRILNHSFDKKGDVHYLIKWKDLPYDQCTWEIDEIDIPYYDNLKQTYWGHRELMLGEDARLPKRLVKKGKKLKD--DKQEK--------PPDTPIVDPTVKFDKQPWYIDSTGGTLHPYQLEGLNWLRFSWAQGTDTILADEMGLGKTVQTIVFLYSLYKEGHSKGPYLVSAPLSTIINWEREFEMWAPDFYVVTYTGDKESRSVIRENEFSFEDNAIRGGKKVFRMKKEVQIKFHVLLTSYELITIDQAILGSIEWACLVVDEAHRLKNNQSKFFRVLNSYKIDYKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGPHMLRRLKADVFKNMPAKTELIVRVELSQMQKKYYKFILTRNFEALNSKGGGNQVSLLNIMMDLKKCCNHPYLFPVAAVEAPMLPNGSYDGSSLVKSSGKLMLLQKMLKKLRDEGHRVLIFSQMTKMLDLLEDFLEYEGYKYERIDGGITGGLRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKRKMMLTHLVVRPGLGSKSGSMTKQELDDILKFGTEELFKDDVEGMMSQGQRPTTPIPDVQSTKGGSLAAGAKKKHGGTPPGDNKDVEDSSVIHYDDAAISKLLDRNQDATDDTELQNMNEYLSSFKVAQYVVREEDGVEEVEREVIKQE-ENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQVNYND-------ASQEDQEWQDELSDNQSEYSIGSEDEDEDFEERPEGQSGRRQSRRQLKSDRDKPLPPLLARVGGNIEVLGFNARQRKAFLNAIMRWGMPPQDAFNSHWLVRDLRGKSEKEFRAYVSLFMRHLCEPGADGAETFADGVPREGLSRQHVLTRIGVMSLVRKKVQEFEHVNGKYSTPDLVPE--------------GPEGKKPGEVISSDPNTPVPASPAQLPPAPLGLPDKMEAQLGYTDEKESGTQKPKKSLEIQALPTALDRVEAEDKHQSSDSKDRAREERMEEVEKAQGSPEQ--PLKEETLPDKEPVPDKLELSLSHSN----------DFRPDDPKAEEKE-------------PTETQQNGD---REEDEEGKKEDKN-GKFKFMFNIADGGFTELHTLWQNEERAAVSSGKIYEIWHRRHDYWLLAGIVTHGYARWQDIQNDPRYMILNEPFKSEVHKGNYLEMKNKFLARRFKLLEQALVIEEQLRRAAYLNMTQDPNHPAMALNARLAEVECLAESHQHLSKESLAGNKPANAVLHKVLNQLEELLSDMKADVTRLPSMLSRIPPVAARLQMSERSILSRLTNRAGDP----TIQQGAFGSSQMYNNSFGPNFRGPGPGGIVNYNQMPLGPYVTGR----------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2A8L1-1", "uniprot_id": "CHD5_MOUSE", "id": "A2A8L1-1", "name": "ATP-dependent chromatin remodeler CHD5", "aln": "MRGPLGTEEELPRLFAEEMENEE-------------------------EMSEEEDGGLEG------FEDFFPAEP-VSLPKKK-PKKLKESKSSKGKRKKKE----GSNDEMSDNEEDLEEKSESEGSDYSPTKKKKKKLKEKKEKKEKKEKRKKRGEDEDDNDDGGLKEPKSSGQLMAEWGLDDVDYLFSEDDYHTLTNYKAFSQFLRPLIAKKNPKIPMSKMMTVLGAKWREFSANNPFK----GSSAAAAAAAVAAAVETVTIAPPLAIS-PQQVPQTLPIRKAKTKEGKGPGVRKKNKGAKDSKKKGRGKRVAGLKFRFGGIS-KRKKGSSSEEDERED-SDLDN----------------ASIHSSSVRSECSAALGK---------------------KNKRR-RKKKRIDDGDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELEKAPEGKWSCPHCEKEGIQWEPKDDDEEEEEGGCEEEEDDHMEFCRVCKDGGELLCCDACPSSYHLHCLNPPLPEIPNGEWLCPRCTCPPLKGKVQRILHWRWTEPPAPFVVGLPGPEVEPGMPPPRPLEGIPEREFFVKWAGLSYWHCSWVKELQLELYHTVMYRNYQRKNDMDEPPPFDYGSGDEDGKSE-KRKNKDPL-------YAKMEERFYRYGIKPEWMMVHRILNHSFDKKGDIHYLIKWKDLPYDQCTWEIDEIDIPYYDNLKQAYWGHRELMLGEDARLPKRLVKKGKKLKD--DKQEK--------PPDTPIVDPTVKFDKQPWYIDATGGTLHPYQLEGLNWLRFSWAQGTDTILADEMGLGKTVQTIVFLYSLYKEGHSKGPYLVSAPLSTIINWEREFEMWAPDFYVVTYTGDKESRSVIRENEFSFEDNAIRGGKKVFRMKKEVQIKFHVLLTSYELITIDQAILGSIEWACLVVDEAHRLKNNQSKFFRVLNSYKIDYKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGPHMLRRLKADVFKNMPAKTELIVRVELSQMQKKYYKFILTRNFEALNSKGGGNQVSLLNIMMDLKKCCNHPYLFPVAAVEAPVLPNGSYDGSSLVKSSGKLMLLQKMLKKLRDEGHRVLIFSQMTKMLDLLEDFLEYEGYKYERIDGGITGGLRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKRKMMLTHLVVRPGLGSKSGSMTKQELDDILKFGTEELFKDDVEGMMSQGQRPTTPIPDIQSTKGGSLTAGAKKKHGSTPPGDNKDVEDSSVIHYDDAAISKLLDRNQDATDDTELQNMNEYLSSFKVAQYVVREEDGVEEVEREVIKQE-ENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQVNYND-------ASQEDQEWQDELSDNQSEYSIGSEDEDEDFEERPEGQSGRRQSRRQLKSDRDKPLPPLLARVGGNIEVLGFNARQRKAFLNAIMRWGMPPQDAFNSHWLVRDLRGKSEKEFRAYVSLFMRHLCEPGADGAETFADGVPREGLSRQHVLTRIGVMSLVRKKVQEFEHVNGKYSTPDLVPE--------------GAEGKKPGEVISSDPNTPVPASPAQLPPAPLGLTDKMEAQLGYTDEKESGMQKPKKSLEIQTLPTALDRVEGEDKHQSSDSKDRAREERTEEVEKAQGSPEQ--PLKEEVLPDKEPIPDKPELSLGHSG----------DFRPDDPKTEEKE-------------PGETQQNGD---REEDEEGKKEDKN-GKFKFMFNIADGGFTELHTLWQNEERAAVSSGKIYEIWHRRHDYWLLAGIVTHGYARWQDIQNDPRYMILNEPFKSEIHKGNYLEMKNKFLARRFKLLEQALVIEEQLRRAAYLNMTQDPNHPAMALNARLAEVECLAESHQHLSKESLAGNKPANAVLHKVLNQLEELLSDMKADVTRLPSMLSRIPPVAARLQMSERSILSRLTNRAGDP----TIQQTSSRRRDFP--LFQRSFPAEPSHLPNPRGREKLQPF--------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDI0-1", "uniprot_id": "CHD5_HUMAN", "id": "Q8TDI0-1", "name": "ATP-dependent chromatin remodeler CHD5", "aln": "MRGPVGTEEELPRLFAEEMENED-------------------------EMSEEEDGGLEA------FDDFFPVEP-VSLPKKKKPKKLKENKC-KGKRKKKE----GSNDELSENEEDLEEKSESEGSDYSPNKKKKKKLKDKKEKK---AKRKKKDEDEDDNDDGCLKEPKSSGQLMAEWGLDDVDYLFSEEDYHTLTNYKAFSQFLRPLIAKKNPKIPMSKMMTVLGAKWREFSANNPFK----GSSAAAAAAAVAAAVETVTISPPLAVS-PPQVPQPVPIRKAKTKEGKGPGVRKKIKGSKDGKKKGKGKKTAGLKFRFGGISNKRKKGSSSEEDEREE-SDFDS----------------ASIHSASVRSECSAALGK---------------------KSKRR-RKKKRIDDGDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELEKAPEGKWSCPHCEKEGIQWEPKDDDDEEEEGGCEEEEDDHMEFCRVCKDGGELLCCDACPSSYHLHCLNPPLPEIPNGEWLCPRCTCPPLKGKVQRILHWRWTEPPAPFMVGLPGPDVEPSLPPPKPLEGIPEREFFVKWAGLSYWHCSWVKELQLELYHTVMYRNYQRKNDMDEPPPFDYGSGDEDGKSE-KRKNKDPL-------YAKMEERFYRYGIKPEWMMIHRILNHSFDKKGDVHYLIKWKDLPYDQCTWEIDDIDIPYYDNLKQAYWGHRELMLGEDTRLPKRLLKKGKKLRD--DKQEK--------PPDTPIVDPTVKFDKQPWYIDSTGGTLHPYQLEGLNWLRFSWAQGTDTILADEMGLGKTVQTIVFLYSLYKEGHSKGPYLVSAPLSTIINWEREFEMWAPDFYVVTYTGDKESRSVIRENEFSFEDNAIRSGKKVFRMKKEVQIKFHVLLTSYELITIDQAILGSIEWACLVVDEAHRLKNNQSKFFRVLNSYKIDYKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGPHMLRRLKADVFKNMPAKTELIVRVELSQMQKKYYKFILTRNFEALNSKGGGNQVSLLNIMMDLKKCCNHPYLFPVAAVEAPVLPNGSYDGSSLVKSSGKLMLLQKMLKKLRDEGHRVLIFSQMTKMLDLLEDFLEYEGYKYERIDGGITGGLRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKRKMMLTHLVVRPGLGSKSGSMTKQELDDILKFGTEELFKDDVEGMMSQGQRPVTPIPDVQSSKGGNLAASAKKKHGSTPPGDNKDVEDSSVIHYDDAAISKLLDRNQDATDDTELQNMNEYLSSFKVAQYVVREEDGVEEVEREIIKQE-ENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQVNYND-------ASQEDQEWQDELSDNQSEYSIGSEDEDEDFEERPEGQSGRRQSRRQLKSDRDKPLPPLLARVGGNIEVLGFNARQRKAFLNAIMRWGMPPQDAFNSHWLVRDLRGKSEKEFRAYVSLFMRHLCEPGADGAETFADGVPREGLSRQHVLTRIGVMSLVRKKVQEFEHVNGKYSTPDLIPE--------------GPEGKKSGEVISSDPNTPVPASPAHLLPAPLGLPDKMEAQLGYMDEKDPGAQKPRQPLEVQALPAALDRVESEDKHESPASKERAREERPEETEKAPPSPEQ--LPREEVLPEKEKILDKLELSLIHSRG------DSSELRPDDTKAEEKE-------------PIETQQNGD---KEEDDEGKKEDKK-GKFKFMFNIADGGFTELHTLWQNEERAAVSSGKIYDIWHRRHDYWLLAGIVTHGYARWQDIQNDPRYMILNEPFKSEVHKGNYLEMKNKFLARRFKLLEQALVIEEQLRRAAYLNMTQDPNHPAMALNARLAEVECLAESHQHLSKESLAGNKPANAVLHKVLNQLEELLSDMKADVTRLPSMLSRIPPVAARLQMSERSILSRLTNRAGDP----TIQQGAFGSSQMYSNNFGPNFRGPGPGGIVNYNQMPLGPYVTDI----------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GT72-1", "uniprot_id": "A0AC58GT72_DANRE", "id": "A0AC58GT72-1", "name": "", "aln": "MQSKLLTFVCFIQLIFELKSVIHYICLPFVLYSYQDSLRRTHSCKLLVFFSDDEEGELQRSVPLSPLERFFSEEDNVKQHKKKKTSKIMEGKEPKVKKKKKKEGLPSGLDDMSDRE-DHGHRSGSESSTYSALKKKKKKPREKKERK-MKQRKKEDDEDEDDDDDGNMKEPKSSSQLMQEWGLEDVQYAFSEDDYKTITNYKAFSQFLRPLIAKKNPKIPMSKMMTVLGAKWREFSANNPFK----GTSATAVAAAVAAAVETVNVAPPICIRSIQQISPTGPIKKAKTKEGKGPGAKKKSKPGKETKKKGKPKKSK----SKAGPGGKRKKGSSSEEDFLDDFSDFDD----------------ISIHSASVRSDTSAAAKK---------------------KSSRKGRKKRKREDGDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELEKAPEGKWSCPHCEKEGIQWEAKDDEEEEDE-VAGEEEDDHMEFCRVCKDGGELLCCDTCPSSYHIHCLNPPLPEIPNGEWLCPRCMCPPLKGKVQKILHWSWGDPPLPPEVPLGPDGEKVDNLAKTPLKGRPERQLFVKWAGLSYWHCSWVSELQLELYHTVMYRNYQRKNDMDEPPPYDYGSGEEELNNE-KRRSKDPQ-------YAAMEERFYRYGIKPEWLIIHRILNHSFDKDGDVQYLIKWRDLPYDQCSWEADDFDVPDYDSLKQAYWDHRNQVLGENHQP--LLFRKGKRPKEEMKRREP--------PPDTPVVDPTIKFEQQPWYIDDTGGTLHPYQLEGLNWLRFSWAQGTDTILADEMGLGKTVQTIVFLYSLYKEGHSKGPFLVSAPLSTIINWEREFEMWAPDFYVVTYTGDKESRAIIRENEFTFEDSAVKSGRKVFRMKKDTPIKFHVLLTSYELITIDQAILGSITWACLVVDEAHRLKNNQSKFFRILNGYKIYYKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGPHMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKFILTRNFEALNSKGGGNQVSLLNIMMDLKKCCNHPYLFPVAAVEAPVLPNGSYDGNLLVKSSGKLTLLQKMLIKLKDGGHRVLIFSQMTKMLDLLEDFLEFEGYKYERIDGGITGGLRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKRKMMLTHLVVRPGLGSKTGSMSKQELDDILKFGTEELFKDDVEAARTMGELKVLEMKSIVLP----LCVPIAEVLNLSSTGDNKEGEEVSVIHYDDNAISKLLDRSQDATEDTEIQNMNEYLSSFKVAQYVVREEDGEEEVQREIIKQE-ENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQVNYND-------ASQEDQEWQDDLSDNQSEYSVGSEDEDEDFEERPEG--GRRHSRRQLKSDRDKPLPPLLARVSGNIEVLGFNARQRKAFLNAIMRWGMPPQDAFNSHWLVRDLRGKSEKEFRAYVSLFMRHLCEPGADGAETFADGVPREGLSRQHVLTRIGVMSLVRKKVQEFEHVNGKFSTPDRIPV--------------GLELKKLTESVSSDPNTPVPASPVPTQPSTPVPSDKTESVSGSQEDKEIAEPENTKPLDPEPVVPEPSPAPEKTNEGEETKNGSPEEKRLEESEKSDTPPVQSEPSANQAPPPTKQCEQPANQTPSDCGKGKETSPERGETKPSPPKTEDKEQKPAIPDDVKSEDPPENQVNGEKDVRDETDEGHRDDKSSIKTRFMFNIADGGFTELHTLWQNEERAAVSSGKIYDIWHRRHDYWLLAGIVTHGYARWQDIQNDPRYAILNEPFKTEMHKGNYLEMKNKFLARRFKLLEQALVIEEQLRRAAYLNMTQDPSHPAMALNTRFAEVECLAESHQHLSKESLAGNKPANAVLHKVLNQLEELLSDMKADVTRLPSMLSRVPPVSARLQMSERGILSRLTSRGNEPPPQQPFPQGSFGCSQMYNSSFAGGFRGPGGTAMVNYSQMPLGPYVSVSSNGPPAPTSLLEKKSSDVLRDVVTPDLKSGKPSDVICIED", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O97159-1", "uniprot_id": "CHDM_DROME", "id": "O97159-1", "name": "ATP-dependent chromatin remodeler Mi-2", "aln": "MASEEENDDNFQEEEEAQEDNAP-----------------------AAELSNDSDAPLKPN---NDEDDDYDPED--SRRKKKGKKRKTRKGEEKGRKKKKR--------KKNESEEDSDFVQHDEEVEYPSTSKRGRKRKEE-----------KQAAKEKESASSGMP---SVEDVCSAFSVCNVEIEYSEEELQSLTTYKAFMHHVRPILQKENPKIAAPKLVMLVAAKWREFCESNPHIQQEGGAAGSGGSAGQARSVTGDEPEEPRSSRSSRNEKPDDIYEEAVEEEEEEEEEEKKPRRKRSGRGKKGRRPSGKVPTLKIKLLGKRKRDSSDEEQDASGASERDSDLEFERMLQKSDDSADEKEAPVSSKADNSAPAAQDDGSGAPVVRKKAKTKIGNKFKKKNKLKKTKNFPEGEDGEHEHQDYCEVCQQGGEIILCDTCPRAYHLVCLEPELDEPPEGKWSCPHCEADGGAAEEEDDDE-------------HQEFCRVCKDGGELLCCDSCPSAYHTFCLNPPLDTIPDGDWRCPRCSCPPLTGKAEKIITWRWAQ---------RSNDDGPSTSKGSKNSNSRVREYFIKWHNMSYWHCEWVPEVQLDVHHPLMIRSFQRKYDMEEPPKFEESLDEADTRYKRIQRHKDKVGMKANDDAEVLEERFYKNGVKPEWLIVQRVINHRTARDGSTMYLVKWRELPYDKSTWEEEGDDIQGLRQAIDYYQDLRAVCTSETTQSRSKKSKKGRKSKLKVEDDEDRPVKHYTPPPEKPTTDLKKKYEDQPAFLEGTGMQLHPYQIEGINWLRYSWGQGIDTILADEMGLGKTIQTVTFLYSLYKEGHCRGPFLVAVPLSTLVNWEREFELWAPDFYCITYIGDKDSRAVIRENELSFEEGAIR-GSKVSRLR-TTQYKFNVLLTSYELISMDAACLGSIDWAVLVVDEAHRLKSNQSKFFRILNSYTIAYKLLLTGTPLQNNLEELFHLLNFLSRDKFNDLQAFQGEFADVSKEEQVKRLHEMLGPHMLRRLKTDVLKNMPSKSEFIVRVELSAMQKKFYKFILTKNYEALNSKSGGGSCSLINIMMDLKKCCNHPYLFPSAAEEATTAAGGLYEINSLTKAAGKLVLLSKMLKQLKAQNHRVLIFSQMTKMLDILEDFLEGEQYKYERIDGGITGTLRQEAIDRFNAPGAQQFVFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRNSVEERVTQVAKRKMMLTHLVVRPGMGGKGANFTKQELDDILRFGTEDLFKE-----------------------------------------DDKE----EAIHYDDKAVAELLDRTNRGIEEKE-SWANEYLSSFKVASYATKEEE--EEEETEIIKQDAENSDPAYWVKLLRHHYEQHQEDVGRSLGKGKRVRKQVNYTDGGVVAADTTRDDSNWQDNGSEYNSEYSAGS-DEDGGDDDFDDQNGAERKAKRRLERRDDRPLPPLLARVGGNIEVLGFNARQRKSFLNAIMRYGMPPQDAFNSQWLVRDLRGKSERNFKAYVSLFMRHLCEPGADNAETFADGVPREGLSRQHVLTRIGVMSLIRKKVQEFEHINGYYSMPELILKPCEPVRSALKQDVAALEAPPTGGNVDKSATTSNSVTPATSAAPSPAPASEKGEDKDKDSEKEKDKTSAEKSEVKQEQEAEEDKKPGDVKQENPVEEAAGDTKPSDAEVKTEVAKTE--PKEETKDPEVKEEPKTEEKEKEKVDDKKPIPPTTVIDDDDDDVMIVKEDGELEKPSASSPKDQKAVAAATSAATGATGKGAEDSLEVLKRKFMFNIADGGFTELHTLWLNEEKAAVP-GREYEIWHRRHDYWLLAGIVTHGYGRWQDIQNDIRFAIINEPFKMDVGKGNFLEIKNKFLARRFKLLEQALVIEEQLRRAAYLNLAQDPSHPAMSLNARFAEVECLAESHQHLSKESLAGNKPANAVLHKVLNQLEELLSDMKSDVSRLPATLARIPPVAQRLQMSERSILSRLAATAGNASN--AAQLMAQFPAGFQGTTLPAFTSGPAGNFANFRPQFSVPGQLSNNSGV-------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . . : . . :*::.:. *: : : * . *** .: . * ::***. . .: * * . .* *.. .*: :* ::: : .*.:. .. : * :: :.: :*: :**:: :::*.**** :.:**:: *:****. .*:: ::.******. .**. *::.:. :*. * :* * . : .:* :* : .** : :. : * : ***:.**.**: . *: *. . . * ::: **. : *...: :*.:. :*:. * :*****************************:***::.*********** :* * :**:: * ****************:***:** .****** **:*:* **** ****.**.::*: * * : . .. *: *:** .:*****.** *:**:::*.:* *.:*** **:*** :: . .: : . : :: ** :*****: *:****::::*::** :.*. **:**::****:.:** : *: . : * . * .* : :**:: : . * **:.* .* . *::.** ::: ** *****:**:****:**.** *************:**:.**********.:**:**:.****::*******:****** :** ***:**::*****::**:.*:: * ** *:: . **:*********::* * **** ** **********.*******:**.*.* ************************: ::**:*:.* ****:***:*:*:**::**********:**:****:*:*:******* ****:******:*:******.**.. **:***************** ** **. ..* *: . *.*::*** **.*** :*: .**************:****** * ************ ***************** ******************************************** :********** *****:******************:*.* ..::********:****:***: *:*: ..***** *:::****.: . ::.* . **********.*..:**: ** : *:***: ** ** ** *********:***:.*.******:******.* ::::*.:***: *: :**** ** *** . :: : ..*:::*:*: *:*********.**************:*******:**********:***********::*:****************.***************************:*********:** :* *: : . * :.....*. ..:*. ... ..: . .:*: . :. : . . . :. . .: : : *: . : : * : . : . . ** : . :* .:. . * :***************** ***:***. *: *:*******************.******** *: *:***** :: ***:**:*****************************::***.****:**:*:*******************************************:**:***: *:*:***: *******.*****: ..:. . : : : . : : ", "identical_positions": 979, "similar_positions": 438, "identity": "45.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120315-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q80T02-1", "uniprot_id": "GPBAR_RAT", "id": "Q80T02-1", "name": "G protein-coupled bile acid receptor 1", "aln": "----MMSHNTT--ELSAIP----------------------------------------RGVQELSLVLASLIVIANLLLALGIVLDRHLRSPPAGCFFLSLLLAGLLTGLALPTLPGLWNRSHQGYWSCLLLHLAPNFCFLSLLANLLLVHGERYMAVLQPLRP-----HGSVRLALFLTWISSLLFASLPALGWNHWSPGAN-------------------------CSSQAIFPAPYLYLEVYGLLLPAVGATALLSVRVLATAHHQLREIRRLERAVCRDAPSTLARALTWRQARAQAGATLLFLLCWGPYVATLLLSVLAYERRPPLGPVTLLSLIS-LGSASAAVVPVAMGLGDQRYTAPWRTAAQRWLQVLRGRPKRANPGPSTAYHSSSQCSTDLDLN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80SS6-1", "uniprot_id": "GPBAR_MOUSE", "id": "Q80SS6-1", "name": "G protein-coupled bile acid receptor 1", "aln": "----MMTPNST--ELSAIP----------------------------------------MGVLGLSLALASLIVIANLLLALGIALDRHLRSPPAGCFFLSLLLAGLLTGLALPMLPGLWSRNHQGYWSCLLLHLTPNFCFLSLLANLLLVHGERYMAVLQPLRP-----HGSVRLALFLTWVSSLFFASLPALGWNHWSPDAN-------------------------CSSQAVFPAPYLYLEVYGLLLPAVGATALLSVRVLATAHRQLCEIRRLERAVCRDVPSTLARALTWRQARAQAGATLLFLLCWGPYVATLLLSVLAYERRPPLGPGTLLSLIS-LGSTSAAAVPVAMGLGDQRYTAPWRTAAQRCLRVLRGRAKRDNPGPSTAYHTSSQCSIDLDLN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TDU6-1", "uniprot_id": "GPBAR_HUMAN", "id": "Q8TDU6-1", "name": "G protein-coupled bile acid receptor 1", "aln": "-----MTPNSTGEVPSPIP----------------------------------------KGALGLSLALASLIITANLLLALGIAWDRRLRSPPAGCFFLSLLLAGLLTGLALPTLPGLWNQSRRGYWSCLLVYLAPNFSFLSLLANLLLVHGERYMAVLRPLQP-----PGSIRLALLLTWAGPLLFASLPALGWNHWTPGAN-------------------------CSSQAIFPAPYLYLEVYGLLLPAVGAAAFLSVRVLATAHRQLQDICRLERAVCRDEPSALARALTWRQARAQAGAMLLFGLCWGPYVATLLLSVLAYEQRPPLGPGTLLSLLS-LGSASAAAVPVAMGLGDQRYTAPWRAAAQRCLQGLWGRASRDSPGPSIAYHPSSQSSVDLDLN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AWA6-1", "uniprot_id": "A0A8M3AWA6_DANRE", "id": "A0A8M3AWA6-1", "name": "", "aln": "MKRMNLYNQSTIRKIVVLPREIKLARPIDCAVPMFSGLTLTADGDGLTIMDPEDKLSREKLIFYLTVPLSSIIIFTNLFIIIGIACNRQLHNTPN-YFFLSLLVADLCTGITLPFIPRMSLDRQLDFRHCLVMYIFPNFLFLSFLFNLVMVHYERYLCIVSPLHHSQFWVHRCFPLALLTVWLPPLLYASLPAFGWNNWIEAASNKSLDSNETFWRSQTSHNASKEDEVCSYKQVFPKAFIYVEVCGLVLPAMLCIVCMTGRVLWIARKQLQDICKLHRAVDRLQTSDQEQQLNLRYAKCVAAVSLTFLVCWVPYIIYQLMSVTALQSGVSLPSSSLYIIMSCTGIGSMAVIPLILGLANKQYTEPIR----RVMLKLRNRWRRG--------HSDRDITI-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : ::* :* *:: *:*:*: :**:: :**. :*:*:..* ******:*.* **::** :* : : .: **:::: *** ***:* **::** ***:.:: **: .. ***: .* .*::*****:***:* *. ** : :** .::*:** **:***: . . :: *** *::** :* :*.*** * .* : *. * *:. *.. * * :** **: *:** * : .* . :* ::* * * *.:*: :**.:::** * * * : * .* * *.. : : ", "identical_positions": 116, "similar_positions": 97, "identity": "28.57%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120316-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P55108-1", "uniprot_id": "GDF10_RAT", "id": "P55108-1", "name": "Growth/differentiation factor 10", "aln": "MAPGLARISLR--SQLLPLVP--LLLLLRGAGCGHRVPSWSSLPSAADSVQRDRDLQQSPGDAAAALGPGAQDIVAVHMLRLYEKYNR---RGAPPGGGNTVRSFRARLDVIDQKPVYFFNLTSMQDSEMILTATFHFYSEPPRWPRAREVFCKPRAKNASCRLLTPGLPARLHLIFRSLSQNTATQGLLRGAMALTPPPRGLWQAKDISSIIKAARRDGELLLSAQLDSGEKDLGVPRPSSHMPYILVYANDLAISEPNSVAVTLQRYDPFPAGDFEPGAAPNSSADPRVRRAAQVSKPLQDNELPGLDERPAPALHAQHFHKHEFWSSPFRALKPRTGRKDRKKKDQDTFTPSSSQVLDFDEKTMQKARRRQWDEPRVCSRRYLKVDFADIGWNEWIISPKSFDAYYCAGACEFPMPKIVRPSNHATIQSIVRAVGIVPGIPEPCCVPDKMNSLGVLFLDENRNVVLKVYPNMSVETCACR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97737-1", "uniprot_id": "GDF10_MOUSE", "id": "P97737-1", "name": "Growth/differentiation factor 10", "aln": "MAPGPARISLG--SQLLPMVP--LLLLLRGAGCGHRGPSWSSLPSAAAGLQGDRDSQQSPGDAAAALGPGAQDMVAIHMLRLYEKYNR---RGAPPGGGNTVRSFRARLEMIDQKPVYFFNLTSMQDSEMILTAAFHFYSEPPRWPRAREVFCKPRAKNASCRLLTPGLPARLHLIFRSLSQNTATQGLLRGAMALTPPPRGLWQAKDISSIIKAARRDGELLLSAQLDTGEKDPGVPRPSSHMPYILVYANDLAISEPNSVAVSLQRYDPFPAGDFEPGAAPNSSADPRVRRAAQVSKPLQDNELPGLDERPAPALHAQNFHKHEFWSSPFRALKPRTGRKDRKKKDQDTFTAASSQVLDFDEKTMQKARRRQWDEPRVCSRRYLKVDFADIGWNEWIISPKSFDAYYCAGACEFPMPKIVRPSNHATIQSIVRAVGIVPGIPEPCCVPDKMNSLGVLFLDENRNAVLKVYPNMSVETCACR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55107-1", "uniprot_id": "GDF10_HUMAN", "id": "P55107-1", "name": "Growth/differentiation factor 10", "aln": "MAHVPARTSPGPGPQLLLLLLPLFLLLLRDVAGSHRAPAWSALPAAADGLQGDRDLQRHPGDAAATLGPSAQDMVAVHMHRLYEKYSR---QGARPGGGNTVRSFRARLEVVDQKAVYFFNLTSMQDSEMILTATFHFYSEPPRWPRALEVLCKPRAKNASGRPLPLGPPTRQHLLFRSLSQNTATQGLLRGAMALAPPPRGLWQAKDISPIVKAARRDGELLLSAQLDSEERDPGVPRPSPYAPYILVYANDLAISEPNSVAVTLQRYDPFPAGDPEPRAAPNNSADPRVRRAAQATGPLQDNELPGLDERP-PRAHAQHFHKHQLWPSPFRALKPRPGRKDRRKKGQEVFMAAS-QVLDFDEKTMQKARRKQWDEPRVCSRRYLKVDFADIGWNEWIISPKSFDAYYCAGACEFPMPKIVRPSNHATIQSIVRAVGIIPGIPEPCCVPDKMNSLGVLFLDENRNVVLKVYPNMSVDTCACR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32U3A0-1", "uniprot_id": "A0AB32U3A0_DANRE", "id": "A0AB32U3A0-1", "name": "", "aln": "MASVCAVAR--------------VLLCLN----------VVKVYLVSSELNGD-----IPAEEPTIHSP-ARDMMTVHMYRVYDKYSKKQQQHQQQLNVNTIRSFRGVPELSHHKVVFHFNLTSVPDSEMILTSNLHY---PDQQSRPRSWACQ-RSRRSSCR-LQYLQTTTPRLIIKASSANAAVPTQLS-NITLPPNRKTLWQTADVSSAMKQAHANAELLISIEFDFGHHKRQEHLPPHNMPFILVYADDIDITEPNSVAGSLQRYSPSPVD---------SKASPLTSRIRREVGHLKENQVPG--------VRYIDLKSGGLWDGAFFAKQ--------NKPLTDIEGSRGSQELTFDEKTMKKARRKQWSEPRVCTRRYLRVDFADIGWSEWILAPKAFDAYYCAGTCAFPIPKVVHPSNHATIQSIVRAVGIVPGVPDPCCVPDKMSSLAVLFLDSSRNMLLKIYPSMSVETCACR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** * .** *. : .: :: * *.: .: .* *:*::::** *:*:**.: : . **:****. :: .:* *:.*****: *******: :*: * : .*. . *: *::.:* * * .: :*:::: * *:*. * ::*.* : ***: *:*. :* *: :.***:* ::* .:. *. *:*****:*: *:****** :****.* *.. ..*.* . * : *::*::** : .::. :* ..* * : .* : . . * * ******:****:**.*****:****:********.***::**:********:* **:**:*:****************:**:*:********.**.*****..** :**:**.***:*****", "identical_positions": 194, "similar_positions": 125, "identity": "40.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120316-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R6T4-1", "uniprot_id": "M0R6T4_RAT", "id": "M0R6T4-1", "name": "MMS19 nucleotide excision repair protein", "aln": "MAAATALEEAAAPMGALCGLVQDFVMGQQEGPADQVAADVKSGGYTVLQVVEALGSSLENPEPRTRARGIQLLSQVLLQCHSLLL-EKEAVHLTLFYENRLKDHHLVVPSVLQGLRALSLSVALPRGLAVSVLKAIFQEVHVQ--SLLQVDRHTVFSIITNFMR------SREEELKSLGADFTFGFIQVMDGEKDPRNLLLAFRIVHDLISKDYNLGPFVEELFEVTSCYFPIDFTPPPNDPYGIQREDLILSLRAVLASTPRFAEFLLPLLIEKVDSEILSAKLDSLQTLNACCAVYGQKELKDFLPSLWASIRREVFQTASERV--------EAEGLAALHSLTACLSCSVLRADAEDLLHPFLSSILQ-DCRHHLCEPDMKLVWP-SAKLLQAAAGASARACEHITSNVLPLLLEQFHKHSQSNQRRTILEMILGFLKLQQKWSYED----------RDERPLSNFKDQLCSLVFMALTDPSTQLQLVGIRMLTVLGAQPDLLSAEDLELAVGHLYRLSLLEEDAQSCRVAALEASGSLATLYPGAFSSHLLPRLAEGLHQGESDVARADGPT----KCSRHFR--CLQALSAVSTHPDIVKETLPLLLQHLCQAHKGNMITESSEVVAVCQSLQQVAEKCQQDPESYWYFHKTAVPCLFALAVQASVPEKASSVLSKALLEDEVLAALASVIGTATTHLSPELAAQSVTCIVPLFLDGNTSFLPENSFPGHFQPFQ--GGSSGQRRLVALLMAFVCSLPRNVEIP-ELTRLMQELLKQSCGHSCPFSSTAASKCFAGLLNKQPPGQQLDEFLQLSVDTVEAGLASESS--RNQAFTLLLWVTKALVLRYHPLSASLTARLMGLLSDPELGCAAADGFSLLMSDCTDVLTRAGHAD---VRIMFRQRFFTDNVPALVQGFH-AAPQDVKPNYLKGLSHVLNRLPKPVLLPELPTLLSLLLEALSCPDSVVQLSTLS-CLQPLLLEAPQIMSLHVDTLVTKFLNLS---SSHSMAVRIAALQCMHALT-RLPTSVLLPFKSQVIRALAKPLDDKKRLVRKEAVSARGEWFLLGSPGS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D071-1", "uniprot_id": "MMS19_MOUSE", "id": "Q9D071-1", "name": "MMS19 nucleotide excision repair protein homolog", "aln": "MAAATGLEEAVAPMGALCGLVQDFVMGQQEGPADQVAADVKSGGYTVLQVVEALGSSLENAEPRTRARGAQLLSQVLLQCHSLLS-EKEVVHLILFYENRLKDHHLVVPSVLQGLRALSMSVALPPGLAVSVLKAIFQEVHVQ--SLLQVDRHTVFSIITNFMR------SREEELKGLGADFTFGFIQVMDGEKDPRNLLLAFRIVHDLISKDYSLGPFVEELFEVTSCYFPIDFTPPPNDPYGIQREDLILSLRAVLASTPRFAEFLLPLLIEKVDSEILSAKLDSLQTLNACCAVYGQKELKDFLPSLWASIRREVFQTASERV--------EAEGLAALHSLTACLSCSVLRADAEDLLGSFLSNILQ-DCRHHLCEPDMKLVWP-SAKLLQAAAGASARACEHLTSNVLPLLLEQFHKHSQSNQRRTILEMILGFLKLQQKWSYED----------RDERPLSSFKDQLCSLVFMALTDPSTQLQLVGIRTLTVLGAQPGLLSAEDLELAVGHLYRLTFLEEDSQSCRVAALEASGTLATLYPGAFSRHLLPKLAEELHKGESDVARADGPT----KCSRHFR--CLQALSAVSTHPSIVKETLPLLLQHLCQANKGNMVTESSEVVAVCQSLQQVAEKCQQDPESYWYFHKTAVPCLFALAVQASMPEKESSVLRKVLLEDEVLAALASVIGTATTHLSPELAAQSVTCIVPLFLDGNTSFLPENSFPDQFQPFQ--DGSSGQRRLVALLTAFVCSLPRNVEIP-QLNRLMRELLKQSCGHSCPFSSTAATKCFAGLLNKQPPGQQLEEFLQLAVGTVEAGLASESS--RDQAFTLLLWVTKALVLRYHPLSACLTTRLMGLLSDPELGCAAADGFSLLMSDCTDVLTRAGHAD---VRIMFRQRFFTDNVPALVQGFH-AAPQDVKPNYLKGLSHVLNRLPKPVLLPELPTLLSLLLEALSCPDSVVQLSTLS-CLQPLLLEAPQIMSLHVDTLVTKFLNLS---SSYSMAVRIAALQCMHALT-RLPTSVLLPYKSQVIRALAKPLDDKKRLVRKEAVSARGEWFLLGSPGS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96T76-1", "uniprot_id": "MMS19_HUMAN", "id": "Q96T76-1", "name": "MMS19 nucleotide excision repair protein homolog", "aln": "-MAAAAAVEAAAPMGALWGLVHDFVVGQQEGPADQVAADVKSGNYTVLQVVEALGSSLENPEPRTRARAIQLLSQVLLHCHTLLL-EKEVVHLILFYENRLKDHHLVIPSVLQGLKALSLCVALPPGLAVSVLKAIFQEVHVQ--SLPQVDRHTVYNIITNFMR------TREEELKSLGADFTFGFIQVMDGEKDPRNLLVAFRIVHDLISRDYSLGPFVEELFEVTSCYFPIDFTPPPNDPHGIQREDLILSLRAVLASTPRFAEFLLPLLIEKVDSEVLSAKLDSLQTLNACCAVYGQKELKDFLPSLWASIRREVFQTASERV--------EAEGLAALHSLTACLSRSVLRADAEDLLDSFLSNILQ-DCRHHLCEPDMKLVWP-SAKLLQAAAGASARACDSVTSNVLPLLLEQFHKHSQSSQRRTILEMLLGFLKLQQKWSYED----------KDQRPLNGFKDQLCSLVFMALTDPSTQLQLVGIRTLTVLGAQPDLLSYEDLELAVGHLYRLSFLKEDSQSCRVAALEASGTLAALYPVAFSSHLVPKLAEELRVGESNLTNGDEPT----QCSRHLC--CLQALSAVSTHPSIVKETLPLLLQHLWQVNRGNMVAQSSDVIAVCQSLRQMAEKCQQDPESCWYFHQTAIPCLLALAVQASMPEKEPSVLRKVLLEDEVLAAMVSVIGTATTHLSPELAAQSVTHIVPLFLDGNVSFLPENSFPSRFQPFQ--DGSSGQRRLIALLMAFVCSLPRNVEIP-QLNQLMRELLELSCCHSCPFSSTAAAKCFAGLLNKHPAGQQLDEFLQLAVDKVEAGLGSGPC--RSQAFTLLLWVTKALVLRYHPLSSCLTARLMGLLSDPELGPAAADGFSLLMSDCTDVLTRAGHAE---VRIMFRQRFFTDNVPALVQGFH-AAPQDVKPNYLKGLSHVLNRLPKPVLLPELPTLLSLLLEALSCPDCVVQLSTLS-CLQPLLLEAPQVMSLHVDTLVTKFLNLS---SSPSMAVRIAALQCMHALT-RLPTPVLLPYKPQVIRALAKPLDDKKRLVRKEAVSARGEWFLLGSPGS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FBU4-1", "uniprot_id": "MMS19_DANRE", "id": "E7FBU4-1", "name": "MMS19 nucleotide excision repair protein homolog", "aln": "---------MAADNNVLLGLVEEFVSGQVDSKAADTSTGVKNGQFTVLQLVEALGVSLTSSQPQTRGRGVQLLSQVLQECYSGLS-EREVEVLIAFYENRLKDHYVITPHVLRGLKALAKCSVLPPGSAVSILKSIFQDVHVQQQSLMVTERSCVYNILISLME------SREEELKGLGADFIFGFVQSVDGERDPRNLLLAFQVAKNIIYRGYDLGKFVEELFEVTSCYFPIDFSPPPNDPHGITQEELILSLRAVLTGTPRFAEFLLPLIIEKMDSDVQSAKVDSMHTLAACGQTYSHKELAEFLPGLWSSIRREVFQTASERV--------ESAGLSALSSLVSCLSRSVLNSDSEDSLQVFLNLVLKSDCQHHLCEPDLKLVWP-SAKLLQAAAGASYRASLIGTQAVIPALLDQYNNRTQCAQRRTLLEVLQGFVQPTPLSRPADGVSCISTHTHEEESVLVAFQQSLCTVVFSALSETSAGLQVTATRVLTALSQQPGLLSQTDVENAVDHLTRLILEEEEAQVS-LAVVECSGSLAHLHPHAFVSRMIPQLKEKILSGRVHTVMEKTLSGSLYECSGAVRRRCVAALASVSSQPSVVQESSPVLLQVLTSAHTGCCGFSVEEVIAVCISLQRIAVHARDNEAIGQFFHDIIIPRLLGLTLQAALQSKDSGHIS-PLTDEAVLSAIVPVISTACAALKPESASRMAAQAVSLFLDGDTSFLPENAFPSQIQPLQSQADSRGPSQLVCLLMACVCSLPRSVEIP-DMDRLLVQLEDLSCTSPHLFSYTFASKCIAGLVNKRPAGAALNAVLDRVLKRVSLELEETSSTHRTQAFTLLIWVAKALLLRYHPLSTALTDKLFSLLSDSALGSLVADGFCVLMNDSPDVLNRDCHAD---VRIMYRQRFFTENSSKLVQGFN-SAEQAKKSCYLKALSHIVNNLPREVQLTELPALLPLLLEALSCVDQGVQLSTLS-CLQPVLLESPAALNTQLEALFTRLLALT---TSPAMKVRMASLRCVHALS-RLPEHMVMPFRARVLKALAAPLDDKKRLVRKEAVAARGEWFLLGSPGG-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q95U54-1", "uniprot_id": "MMS19_DROME", "id": "Q95U54-1", "name": "MMS19 nucleotide excision repair protein", "aln": "---------MTTPTRATLEKALKSDQKLVN-SATQIAKDLTAKAYDISALAEALGFALSSPDMEERVAGTNLLSAVLIALPQDLLQERQLEFLSTFYMDRLRDHHNVMPAIIDGIDALVHMKALPRAQIPQILQSFFEHTTCQ--SQTRSDRTKLFHIFQYLTE------NFQDELQAMAGDFVYGLINSIDGERDPRNLDIIFSFMPEFLS-TYPLLHLAEEMFEIFACYFPIDFNPSKQDPAAITRDELSKKLTNCLVANNEFAEGTVVLAIEKLESELLVAKLDSIELLHQAAVKFPPSVLEPHFDQIWQALKTETFPGNDN----------EEILKASLKALSALLER---AAHIPDISHSYQSSILG-VILPHLSDVNQRLFHP-ATGIALVCVSG--DAPYAADKILNSFLLKLQAADASSEQRIKIYYIVSQVYKLSALR--------------------GSLQKLDTTIRESVQDDVIASLRLIEQEEFDAKKE-----------------------DLELQKAALSVLNESAPLLNEKQRALIYKALVQLVSHPSIDIDFTTLTVSLG-------------ALQPVEVQSNFIDVCVRNFEIFSTFVKRKIYTNLLPLMPQIAFTQRILDLVMTQTFNDTT-------AEPVRLLALEALNKLLLLADQRFIVDVQQESNLLHKLIELGQKTEGLSMQSLEQIAGALS--RITQQLPLSEQSAIVSEYLPGLN----LSQSADLYITKGLLGYLHKDITLDDHFERLLTDLTQLSLNSDNEQLRVIAHHLLCSMVNKMESNPANLRKVKKITEQLKVAIKKGDVR----AVEILAWVGKGLVVAGFDEAADVVGDLSDLLKHPSLSTAAALGFDIIAAEYP----ELDLPV---VKFLYKQKLFHT----IMGKMG-SKLANYCVHHLKAFVYVLKATPQAVIKLNIEQLGPLLFKSLEEHNEAQSLCIALGICEKFVAQQDTYFQGHLAHLIPSCLELSKYKAQHTMQVRIAALQLLYDVT-KYPTFVLLPHKVDVTLALAAALDDPKRLVRNTAVKARNAWYLVGAPSPN", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40469-1", "uniprot_id": "MET18_YEAST", "id": "P40469-1", "name": "DNA repair/transcription protein MET18/MMS19", "aln": "-----MTPDELNSAVVTFMANLNIDDSKANETASTVTDSIVHRSIKLLEVVVALKDYFLSENEVERKKALTCLTTILAKTPKDHLSKNECSVIFQFYQSKLDDQALAK-EVLEGFAALAPMKYVSINEIAQLLRLLLDNYQQG--QHLASTRLWPFKILRKIFDRFFVNGSSTEQVKRINDLFIETFLHVANGEKDPRNLLLSFALNKSITSSLQNVENFKEDLFDVLFCYFPITFKPPKHDPYKISNQDLKTALRSAITATPLFAEDAYSNLLDKLTASSPVVKNDTLLTLLECVRKFGGSSILENWTLLWNALKFEIMQNSEGNENTLLNPYNKDQQSDDVGQYTNYDACLKIINLMALQLYNFDKVSFEKFFTHVLDELKPNFKYEKDLKQTCQILSAIGSGNVEIFNKVISSTFPLFLINTSEVAKLKLLIMNFSFFVDSYIDLFGR----------------TSKESLGTPVPNNKMAEYKDEIIMILSMALTRSSKAEVTIRTLSVIQFTKMIKMKGFLTPEEVSLIIQYFTEEILTDNNKNIYYACLEGLKTISEIYEDLVFEISLKKLLD-----------LLPDCFEEKIRVNDEENIHIETILKIILDFTTSRHILVKESITFLATKLNRVAKIS--KSREYCFLLISTIYSLFNNNNQNENVLNEEDALALKNAIEPKLFEIITQESAIVSDNYNLTLLSNVLFFTNLKIPQAAHQEELDRYNELFISEGKIRILDTPNVLAISYAKILSALNKNCQFPQKFTVLFGTVQLLKKHAPRMTETEKLGYLELLLVLSNKFVSEKDVIGLFDWKDLSVIN-----------LEVMVWLTKGLIMQNSLESSEIAKKFIDLLSNEEIGSLVSKLFEVFVMDISSLKKFKGISWNNNVKILYKQKFFGDIFQTLVSNYKNTVDMTIKCNYLTALSLVLKHTPSQSVGPFINDLFPLLLQALDMPDPEVRVSALE-TLKDTTDKHHTLITEHVSTIVPLLLSLSLPHKYNSVSVRLIALQLLEMITTVVPLNYCLSYQDDVLSALIPVLSDKKRIIRKQCVDTRQVYYELGQIPFE", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . : * : .: : :. ** : . : * . *: :* :.: : ** .:* *: :: *: ** :. .:*: :::. . * : *: : . :::: : * ::: :**:***** : * . .: : : *::*:: ***** *.*. :** * .::* * :... *** ::*: :. .* *:: * . : . : :* ::: * : . : : : . : * : . .: .. . . : . : :. : .: : . :. .: : : : : : : . . : . . . . : : .: * : . *: : : * . . : . . : * :. : .: *: : . :: . :. . :: *: *.*:: :: :. : .**.. :. .: * :: : . . *:::::*::* :: : :*..: ::: * : * .**:::*. : :. : : : :: :.. * *: :: **: :*: : :: * :..: * ** *.* **::*: .* :* :: :* ", "identical_positions": 86, "similar_positions": 235, "identity": "7.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120323-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M495-1", "uniprot_id": "F1M495_RAT", "id": "F1M495-1", "name": "Secretory phospholipase A2 receptor", "aln": "---------MAQWLAMLQLLWLQQLLLG-VHQGSAQDLTHTQELA--LEWRDKGIFIIQSESLKTCIQAGKSVLTLENCTQPNEYMLWKWVSDNHLFNVGASGCLGLNISDLKRPLSLYECDSTLISLRWLCDRKTIVGPLQYKVQVN-HSTVVA-KKTPHKWSAYMPGGGDICEHLHRDIYTLKGNAHGMPCVFPFQFKGQWHHECIREGHKEHLLWCATTSRYEEDEKWGFCPDPTSTEIFCDAMWQRNDNSHICYQFNLLSSLSWNEAHSSCQMQGGALLSITDENEEAFIRKELSRVAKEVWTGLNQLDEMAGWQWSDGTPLSYLNWSQEVTAGPFVEYHCGTLKVAS-ATWRSMDCESTLPYICKRHLNHTAEDILQKDSWKYHTTHCDPGWTPFNRKCYKLKKEKRTWQEALHSCQSDDSMLMDVTSLAEVELLVNLLGDENASETWIGLSSNKIPVSFAWSSGSSVIFTNWYLLEPRILPNRRQLCVSADQSDGRWKVKGCKETLPYICKKAGQVLE----DEDSGCQAGWERHGKYCYKIDTVLRSFEQASGGYYCPPALLTITSRFEQAFITSLISSVAR-KDSYFWIALQDQNNTGEYTWKTMGQR-EPVQYTHWNAHQPSYHGGCVVLRGGSSFGRWEVKNCSDFKAMSLCKTPIKVWEKTEFEGRWP--FHPCYMDWESETGLASCFKVFHSEKVLMKRSWREAEAFCEEFGAHLASFAHIEEENFVNKLLHSKFNWTQERQFWIGFNKRNPLNAGSWEWSDGSPVVSSFLDNAYFEEDAKNCAVYKANNTLLPSNCASKHEWICKIPRDVKPNFPVWY-QYDAPWLFYQNAEYLFHTHPAEWATFEFVCGWLRSDFLTIYSAQEQEFIHSKIRALSKYGANWWIGLEDRRAGDQIHWSNGSPVIFQNWDKGRKGRMDSQRKRCVFMSAITGLWGTENCSVPMPSICKRVKIWVIEKEK-PPTQHGTCPKGWLYFNYKCFLVTIPKDPRELKTWTGAQEFCAAKGGTLVSIESELEQAFITVNLFGQTTNVWIGLQSDNHENWVNGKPVVYSNWSPSDVINIPNYNTTEVQKRAPLCALMSSNPNFHFTGKWYFDDCGKKGYGFVCEKMQDTLENHVNVSDTYAVPSTLEYGNRTYKIIRANMTWYAAGKSCRMQGAELVSIPDVFHQSFLTVLLSRLGHAHWIGLSTPDNGLNFDWSDGTKSPFTYWKD-----EESASLGDCVFADTDGHWHGTACESHLQGAVCRVLT-ETKSFEHPVLCSETSVPWIRFKGHCYSFSTVLDSRSFEDAREFCKREG--SNLLAIKDEAENLFLLEELLALGSSVQMVWLNAQLDNDNKTLRWFDGAATEQSNWGVRKPDMDHLKPHPCVVLRIPEGVWQSTPCEDKTGFICKVEAG-IPAVTAHPEKGLSHSIMPVAAALALTIVLGILVLCLWIYKQNGGAILPRLTGSRGPYYPMSSFSMAHLEENILISDLEKNNQ-------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62028-1", "uniprot_id": "PLA2R_MOUSE", "id": "Q62028-1", "name": "Secretory phospholipase A2 receptor", "aln": "---------MVQWLAMLQLLWLQQLLLLGIHQGIAQDLTHIQEPS--LEWRDKGIFIIQSESLKTCIQAGKSVLTLENCKQPNEHMLWKWVSDDHLFNVGGSGCLGLNISALEQPLKLYECDSTLISLRWHCDRKMIEGPLQYKVQVKSDNTVVA-RKQIHRWIAYTSSGGDICEHPSRDLYTLKGNAHGMPCVFPFQFKGHWHHDCIREGQKEHLLWCATTSRYEEDEKWGFCPDPTSMKVFCDATWQRNGSSRICYQFNLLSSLSWNQAHSSCLMQGGALLSIADEDEEDFIRKHLSKVVKEVWIGLNQLDEKAGWQWSDGTPLSYLNWSQEITPGPFVEHHCGTLEVVS-AAWRSRDCESTLPYICKRDLNHTAQGILEKDSWKYHATHCDPDWTPFNRKCYKLKKDRKSWLGALHSCQSNDSVLMDVASLAEVEFLVSLLRDENASETWIGLSSNKIPVSFEWSSGSSVIFTNWYPLEPRILPNRRQLCVSAEESDGRWKVKDCKERLFYICKKAGQVPA----DEQSGCPAGWERHGRFCYKIDTVLRSFEEASSGYYCSPALLTITSRFEQAFITSLISSVAE-KDSYFWIALQDQNNTGEYTWKTVGQR-EPVQYTYWNTRQPSNRGGCVVVRGGSSLGRWEVKDCSDFKAMSLCKTPVKIWEKTELEERWP--FHPCYMDWESATGLASCFKVFHSEKVLMKRSWREAEAFCEEFGAHLASFAHIEEENFVNELLHSKFNWTQERQFWIGFNRRNPLNAGSWAWSDGSPVVSSFLDNAYFEEDAKNCAVYKANKTLLPSNCASKHEWICRIPRDVRPKFPDWY-QYDAPWLFYQNAEYLFHTHPAEWATFEFVCGWLRSDFLTIYSAQEQEFIHSKIKGLTKYGVKWWIGLEEGGARDQIQWSNGSPVIFQNWDKGREERVDSQRKRCVFISSITGLWGTENCSVPLPSICKRVKIWVIEKEK-PPTQPGTCPKGWLYFNYKCFLVTIPKDPRELKTWTGAQEFCVAKGGTLVSIKSELEQAFITMNLFGQTTNVWIGLQSTNHEKWVNGKPLVYSNWSPSDIINIPSYNTTEFQKHIPLCALMSSNPNFHFTGKWYFDDCGKEGYGFVCEKMQDTLEHHVNVSDTSAIPSTLEYGNRTYKIIRGNMTWYAAGKSCRMHRAELASIPDAFHQAFLTVLLSRLGHTHWIGLSTTDNGQTFDWSDGTKSPFTYWKD-----EESAFLGDCAFADTNGRWHSTACESFLQGAICHVVT-ETKAFEHPGLCSETSVPWIKFKGNCYSFSTVLDSRSFEDAHEFCKSEG--SNLLAIRDAAENSFLLEELLAFGSSVQMVWLNAQFDNNNKTLRWFDGTPTEQSNWGLRKPDMDHLKPHPCVVLRIPEGIWHFTPCEDKKGFICKMEAG-IPAVTAQPEKGLSHSIVPVTVTLTLIIALGIFMLCFWIYKQKS-DIFQRLTGSRGSYYPTLNFSTAHLEENILISDLEKNTNDEEVRDAPATESKRGHKGRPICISP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13018-1", "uniprot_id": "PLA2R_HUMAN", "id": "Q13018-1", "name": "Secretory phospholipase A2 receptor", "aln": "---------------MLLSPSLLLLLLLGAPRGCAEGVAAALTPERLLEWQDKGIFVIQSESLKKCIQAGKSVLTLENCKQANKHMLWKWVSNHGLFNIGGSGCLGLNFSAPEQPLSLYECDSTLVSLRWRCNRKMITGPLQYSVQVAHDNTVVASRKYIHKWISYGSGGGDICEYLHKDLHTIKGNTHGMPCMFPFQYNHQWHHECTREGREDDLLWCATTSRYERDEKWGFCPDPTSAEVGCDTIWEKDLNSHICYQFNLLSSLSWSEAHSSCQMQGGTLLSITDETEENFIREHMSSKTVEVWMGLNQLDEHAGWQWSDGTPLNYLNWSPEVNFEPFVEDHCGTFSSFMPSAWRSRDCESTLPYICKKYLNHIDHEIVEKDAWKYYATHCEPGWNPYNRNCYKLQKEEKTWHEALRSCQADNSALIDITSLAEVEFLVTLLGDENASETWIGLSSNKIPVSFEWSNDSSVIFTNWHTLEPHIFPNRSQLCVSAEQSEGHWKVKNCEERLFYICKKAGHVLS----DAESGCQEGWERHGGFCYKIDTVLRSFDQASSGYYCPPALVTITNRFEQAFITSLISSVVKMKDSYFWIALQDQNDTGEYTWKPVGQKPEPVQYTHWNTHQPRYSGGCVAMRGRHPLGRWEVKHCRHFKAMSLCKQPVENQEKAEYEERWP--FHPCYLDWESEPGLASCFKVFHSEKVLMKRTWREAEAFCEEFGAHLASFAHIEEENFVNELLHSKFNWTEERQFWIGFNKRNPLNAGSWEWSDRTPVVSSFLDNTYFGEDARNCAVYKANKTLLPLHCGSKREWICKIPRDVKPKIPFWY-QYDVPWLFYQDAEYLFHTFASEWLNFEFVCSWLHSDLLTIHSAHEQEFIHSKIKALSKYGASWWIGLQEERANDEFRWRDGTPVIYQNWDTGRERTVNNQSQRCGFISSITGLWGSEECSVSMPSICKRKKVWLIEKKKDTPKQHGTCPKGWLYFNYKCLLLNIPKDPSSWKNWTHAQHFCAEEGGTLVAIESEVEQAFITMNLFGQTTSVWIGLQNDDYETWLNGKPVVYSNWSPFDIINIPSHNTTEVQKHIPLCALLSSNPNFHFTGKWYFEDCGKEGYGFVCEKMQDTSGHGVNTSDMYPMPNTLEYGNRTYKIINANMTWYAAIKTCLMHKAQLVSITDQYHQSFLTVVLNRLGYAHWIGLFTTDNGLNFDWSDGTKSSFTFWKD-----EESSLLGDCVFADSNGRWHSTACESFLQGAICHVPP-ETRQSEHPELCSETSIPWIKFKSNCYSFSTVLDSMSFEAAHEFCKKEG--SNLLTIKDEAENAFLLEELFAFGSSVQMVWLNAQFDGNNETIKWFDGTPTDQSNWGIRKPDTDYFKPHHCVALRIPEGLWQLSPCQEKKGFICKMEAD-IHTAEALPEKGPSHSIIPLAVVLTLIVIVAICTLSFCIYKHNG-GFFRRLAGFRNPYYPATNFSTVYLEENILISDLEKSDQ-------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B1X5-1", "uniprot_id": "A0A8M2B1X5_DANRE", "id": "A0A8M2B1X5-1", "name": "", "aln": "MRGYSKTLQVRFHEALSVLYVLLYVSNFALAAAEVSDKTEVWDKTQLLEVYSKGVFRLESVSQKRCLSADSSGLSMSSCDPSSPALLWKWVSRHRLYNLGTSRCLGINTTK-QHDVGIFECDVSLPSMWWRCGGGMLYGAMN-NKLVAVDSKVVVRRGALHQWRIFGAAGEGPCAYPYEDIHTLQGNSHGMTCSIPFNYNNKWFWDCTSEGREDRHLWCATTNRYDQDEKWGFCPNPVSG---CNEFWESHPELNACYQFNLYSILTWSQALTSCQAQGGSLLSITQSSEQNYIKGRLSDMGVMVWIGLNHLSQHGGWQWSDGSPLSLVGYTADLSSTPVQQNQQCGLFNSTLGSWQSLSCESALPYICKKTTNYSRNAEP-LDNWQYKETICPDGWLDHNGFCYLYLKEKASWDNSSSACRALEAELVSIHSLSQQEVLLKLLSLEPNSKVWIGLHKEATLQTVQWSDKSPVKFISWNSQEPTRRYDDKRICVTADPKQGRWQFEECEEQNAAICKASGLVPQRPAGEWDEGCPEGWRRKDNWCYKITDQEQTFQDAVKGYYCKSPLVTIESRFEQAFLKSLISEMGGSDSQYYWTALQDLNRTEEYRWLTQNGSTTPLTYTNWNRHQPVSLGACVVMSGGRALGHWEVKNCHTFKALAVCKQEVSGDHDTLTPAPHIDINAACPTGWESHSGLSHCYKVYHDEKILMQRTWTEAEFFCRTLGADLASFHHYEDQAFVKKILSVMFQSTEGRWFWVGFTKRNPSSDGAWEWSDGTPVVTSFIEDMNEADSHMCAAYSDLTNTLTPHSCDSKYEWICKVPRGVELVKPYWYSDQHAPWFFFHEAEYYFASKQFPWQSVSFTCKMMGADLLSIHSSEELDFVKGHITKDSEY---WWIGLSANSGHNGLSWTDGSALDYENWENGQFSRKPGQN--CIQMSAQSGQWSAGSCKDPRGYVCKRRTVSVVEVPQ-EPYYIGSCPENWLYYGHKCLYVYLPDRPEKGKSWQEAQAVCSANQGSLVSIKDEIEQAYIVMMLHGSSAGVWIGVQGRFSSKWSNKKPIVYSNWER---INYRSP-------EVPHCTFLSNSHNFRLTGIWQDDVCTEKIYGFVCEKAQDTTKRPTHSYHTASSLGTSEFRNHTYLVAHGNMSWYEAQERCLVKGATLVSITDPFQQAYLTFLINRLDAPHWIGLYSTDDGISHQWSDGSEGWFTHWEDSNYYPEGPVGDGGCVSMDTNGRWRDNECDMRLSGAICYIPPPKSIAFSFEVVCPDT---WVKFRGSCYYFKTVISKKTQEEARNHCKANGNSSELLTIQDDEESRFFLKEMWHYYQGPQNLWLGVLYNDKNGVLARLDGSQLQYTNWRSRVPDEQEMRKQPCVSMRVSDAVWQLADCTERLGFICKTSTGTIKEVEVEPLKGLHQGVISVAALVAILLFAVVIGSLWLLYKRNS-LCFRRLPTFGSAYYRQTNSQASDQDENVLLPELETQAGD------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : . ... : ** .**:* ::* * * *:.*..* *::..* .. :****** . *:*:* * ***:* : :: : ::*** :* *: * *. : *.:: . * ...**. : *:* : ..* . * : .*::*::**:***.* :**::: :*. :* **::: ******.**:.********:*.* *: *: . . . ****** * *:*.:* :** ***:****::. *: :*: .:* ** ***:*.: .*******:**. :.:: ::. *. : : : .:*:* .***:******: *: . * *:* * * .* .* ** *:. :* : :*:: :: *:.: **:: *.*:.** * *:.**** .: :. **. *.* * .* ** : ::**:*: .:*:*:.: *:* *** :* * : :.** **.*:. :**** ::*::* **** ..*:** .******:.****.: ...*:* **** * * ** * . . *: ** ** :** *.**.: * .:*:****.* ***:::** :. ..: .* .*** .**: *:**:*.**:**:*:* *** **. :**.**** * *:: **:::* *: *: * **:**.:*** . *:* *** :***:**::: :. .* . .:** * * ** ****::**.*. * ** : ..**:*:::*** * : * ...*.* : :*:*:*:*:.* :*::.:* ::* *****. . : : * :*:.: ::**:.*: .* * :*: :* *.: .*. . :*** .: ::* : * *:**:.***:.:**: : :*. * . *.* ** .* : *:**:*:.*:***:*.: *.*.::.****:*. ..* * **:*****. ** . . * *:::*.. **::** * : * :: ******* *** . .: . . .* *: *:** : ..**:** * : * :: * *.**.* ::*::**.::.**. .***** :.*:* ..:****::. **.*:* * . *.*. *::*:*:.. *: *.**:* : . :: .. :*.:* *::*:. ** *.**:.. : * *::.** :* *:**:*:* *. *:*:*: .. * :**.. :..* .: :**: : :** * ** : :: : ** :*:.:.:*: : * :: ***** .:. * . . * ** :.::.::. ::: : : :**::. : **. ..** . . :**:*:.:**.. ", "identical_positions": 508, "similar_positions": 481, "identity": "33.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120327-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1MAB7-1", "uniprot_id": "DGKI_RAT", "id": "F1MAB7-1", "name": "Diacylglycerol kinase iota", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAAGRGCHLLPLPAARGPARAP--AASSALSPAGLCSGTASASSAAAGAVAMNPSSSAGEERGATGGSSS------------------------------SGSGAGSCCLGAEGGVDPRGAG---AAAAAALEEPAAAGQ-----KEKEEALEEKLRDLTFRKQVSYRKAISRTGLQHLAPAHP-------------------------------------------LGLPVANGPAKEPRATLDWSENAVNGEHLWLETNVSGDLCYLGEENCQVRFAKSALRRKCAVCKIVVHTACIEQL-EKINFRCKPTFREGGSRSPRE-NFVRHHWVHRRRQEGKCKQCGKGFQQKFS-----FHSKEIVAISCSWCKQAFHNKVTCFMLHHIEEPCSLGAHAAVIVPPTWIIKVKKP---QNSLKASNRK------------------KKRTSFKRKASKRGTEQENKGRPFVIKPISSPLMKPLLVFVNPKSGGNQGTKVLQMFMWYLNPRQVFDLSQEGPKDALELYRKVPNLRILACGGDGTVGWILSILDELQ--LSPQPPVGVLPLGTGNDLARTLNWGGGYTDEPVSKILCQVEDGTIVQLDRWNLHVERNPDLPPEELEDGVCKLPLNVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGAAFSDFLQRSSRDLSKHVKVVCDGTDLTPKIQDLKFQCIVFLNIPRYCAGTMPWGNPGDHHDFEPQRHDDGYIEVIGFTMASLAALQVGGHGERLHQCREVMLLTYKSIPMQVDGEPCRLAPAMIRISLRNQANMVQKSKRRTSMPLLND---------------------PQSVPDRLRIRVNKISLQDYEGLHYDKEKLREASIPLGILVVRGDCDLETCRMYIDRLQEDLQSVSSGSQRVHYQDQETSFPRAISAQRLSPRWCFLDATSADRFYRIDRSQEHLHFVMEISHDEIFILDPDMVVSQQAGTPPGMPDLVVEQASGLSDWWNPALRKRMLSDS--GMITPHYEDSDLKDFSHSRVLQSPVSSEDHAILQAVITGDLMKLMESYKNGGSLLIQGPGHCSLLHYAAKTGNGEIVKYILDHGPAELLDMADSETGETALHKAACQRNRAVCQLLVDAGASLRQTDSKGKTPQERAQQAGDPDLAAYLESRQNYKIIGHEDLETAV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3YWQ0-2", "uniprot_id": "DGKI_MOUSE", "id": "D3YWQ0-2", "name": "Diacylglycerol kinase iota", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAAGRGCHLLPLPAARGPARAP--AASSALSPTGLCSGTTSASFAAAGAVAMNPSSSAGEERGATGGSSS------------------------------SGSGAGSCCLGAEGGADPRGAG---AAAAAALEEPAAAGQ-----KEKEEALEEKLRDLTFRKQVSYRKAISRTGLQHLAPAHP-------------------------------------------LGLPVANGPAKEPRATLDWSENAVNGEHLWLETNVSGDLCYLGEENCQVRFAKSALRRKCAVCKIVVHTACIEQL-EKINFRCKPTFREGGSRSPRE-NFVRHHWVHRRRQEGKCKQCGKGFQQKFS-----FHSKEIVAISCSWCKQAFHNKVTCFMLHHIEEPCSLGAHAAVIVPPTWIIKVKKP---QNSLKASNRK------------------KKRTSFKRKASKRGTEQETKGRPFVIKPISSPLMKPLLVFVNPKSGGNQGTKVLQMFMWYLNPRQVFDLSQEGPKDALEMYRKVPNLRILACGGDGTVGWILSILDELQ--LSPQPPVGVLPLGTGNDLARTLNWGGGYTDEPVSKILCQVEDGTIVQLDRWNLHVERNPDLPPEELEDGVCKLPLNVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGAAFSDFLQRSSRDLSKHVKVVCDGTDLTPKIQDLKFQCIVFLNIPRYCAGTMPWGNPGDHHDFEPQRHDDGYIEVIGFTMASLAALQVGGHGERLHQCREVMLLTYKSIPMQVDGEPCRLAPAMIRISLRNQANMVQKSKRRTSMPLLND---------------------PQSVPDRLRIRVNKISLQDYEGLHYDKDKLREASIPLGILVVRGDCDLETCRMYIDRLQEDLQSVSSGSQRVHYQDQETSFPRALSAQRLSPRWCFLDATSADRFYRIDRSQEHLHFVMEISHDEIFILDPDMVVSQQAGTPPGMPDLVVEQASGLSDWWNPALRKRMLSDS--GMITPHYEDSDLKDFSHSRVLQSPVSSEDHAILQAVLTGDLMKLMESYKNGGSLLIQGPGHCSLLHYAAKTGNGDIVKYILDHGPAELLDMADSETGETALHKAACQRNRAVCQLLVDAGASLRQTDSKGKTPQERAQQAGDPDLAAYLESRQNYKIIGHEDLETAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75912-2", "uniprot_id": "DGKI_HUMAN", "id": "O75912-2", "name": "Diacylglycerol kinase iota", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDAAGRGCHLLPLPAARGPARAPAAAAAAAASPPGPCSGAACAPSAAAGAGAMNPSSSAGEEKGATGGSSS------------------------------SGSGAGSCCLGAEGGADPRGAGSAAAAGAAALDEPAAAGQ-----KEKDEALEEKLRNLTFRKQVSYRKAISRAGLQHLAPAHP-------------------------------------------LSLPVANGPAKEPRATLDWSENAVNGEHLWLETNVSGDLCYLGEENCQVRFAKSALRRKCAVCKIVVHTACIEQL-EKINFRCKPTFREGGSRSPRE-NFVRHHWVHRRRQEGKCKQCGKGFQQKFS-----FHSKEIVAISCSWCKQAFHNKVTCFMLHHIEEPCSLGAHAAVIVPPTWIIKVKKP---QNSLKASNRK------------------KKRTSFKRKASKRGMEQENKGRPFVIKPISSPLMKPLLVFVNPKSGGNQGTKVLQMFMWYLNPRQVFDLSQEGPKDALELYRKVPNLRILACGGDGTVGWILSILDELQ--LSPQPPVGVLPLGTGNDLARTLNWGGGYTDEPVSKILCQVEDGTVVQLDRWNLHVERNPDLPPEELEDGVCKLPLNVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGAAFSDFLQRSSRDLSKHVKVVCDGTDLTPKIQELKFQCIVFLNIPRYCAGTMPWGNPGDHHDFEPQRHDDGYIEVIGFTMASLAALQVGGHGERLHQCREVMLLTYKSIPMQVDGEPCRLAPAMIRISLRNQANMVQKSKRRTSMPLLND---------------------PQSVPDRLRIRVNKISLQDYEGFHYDKEKLREASIPLGILVVRGDCDLETCRMYIDRLQEDLQSVSSGSQRVHYQDHETSFPRALSAQRLSPRWCFLDATSADRFYRIDRSQEHLHFVMEISQDEIFILDPDMVVSQPAGTPPGMPDLVVEQASGISDWWNPALRKRMLSDSGLGMIAPYYEDSDLKDLSHSRVLQSPVSSEDHAILQAVIAGDLMKLIESYKNGGSLLIQGPDHCSLLHYAAKTGNGEIVKYILDHGPSELLDMADSETGETALHKAACQRNRAVCQLLVDAGASLRKTDSKGKTPQERAQQAGDPDLAAYLESRQNYKVIGHEDLETAV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ARE4-1", "uniprot_id": "A0A8M3ARE4_DANRE", "id": "A0A8M3ARE4-1", "name": "Diacylglycerol kinase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMDPLADMRASRAERSGRGAAGGESA------------------------------EDQTRGCGKNAAMGGSD------------------SLSSF-----ADMDDSLEDKLKGLAFRKQISYRKAISRSGLQHLGPAQN-------------------------------------------PFPALSNGPAKELRNTVDWSENAVNGDHLWLETNCSGELCYLGEETCVAKIAKSAPRRKCAACKIVVHTACIEEL-DKINFRCKPTFREGSSRCLRDQNVLRHHWVHRRRQEGKCRQCGKSFPQKF------FHSKEIVAISCSWCKQAFHNKVTCFMLHQIEEPCSLGAHAGVIVPPSWIIKVRKP---QSSFKNSTRR------------------KKRTSFKRRASKKGTD-ESKWRPFMLKPLPSPLMKPVLVFVNPKSGGNQGTKLLQMFMWILNPRQVFDLSQGGPRDALELYRKVPNLRILACGGDGTVGWILSALDELQ--MNPQPPVAVLPLGTGNDLARTLNWGGGYTDEPVSKVLCHVEDGSVVQLDRWNLQVERS----VVQHEEGTQKLPLNVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRNKMFYAGAAFSDFLQRSSRDLSKHVRVVCDGTDLTAKIQELKFQCIVFLNIPRYCAGTMPWGNTGDHRDFEPQRHDDGCIEVIGFTMASLAALQVGGHGDRLHQCREVLITTFKTLPVQVDGEPCRLAPSTLRISLRNQANMVQKSKRRTSVPLLNDIQKVCAADLRRLSAPPDSFSVPHAVPERLRLRVNRIGLQDYDSMQFDKERLRDISTAVGIVVVRGDCDLETCRLYIDRLQEDLHQAPSAGHRVHYQDECAGLPRPSSAHRLSANWSFLDSTSADRFYRIDKAQEHLHFVTEICQDEVYILDHEAPAVSQVRAP-GMPDVVVEPSSGV-----------------------------------------PLTSDEQALLSAAAKGDLTAVSSSCRSGLSLLVRDAMGCTALHLAAHHGHADVVSFILEHGSKLMLDLTERDTGDTALHKAAAQQQRDVCKRLLEAGASPHKTNFLGKTPKDCALDAGNLELASMLEIQAVDEPASHEDLETAV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q09103-1", "uniprot_id": "DGK2_DROME", "id": "Q09103-1", "name": "Eye-specific diacylglycerol kinase", "aln": "MQQQQQPSIDQLPEPTASTSNSATTKPTIATATTSTTTTSGNNFHQQLQATTAATMQRLRTTFTRSRTPTGAEMKMQNSLEVPKQVRSASFDEMQLESQRASSSLLKQQSSSSASADERSSEAGFLQVPLAAHQQRSHSFDSATASAGSDDSGTFLEVPRRLKARRSSSTKTPPPCIHCHYLEEYERRMTAEQRYFIDHRELTALSYSNTSSEASEDEDEVEGHNAEEEEEGSAAIEDAEEETTEAATEEADEDPRTEVESEHDHDPDDDAALEMDIRIGNMSQGSSIEESRARLPRQMRRHTIGSSSVTSASEDEGLEGSDNGSPHFGNTLLPPQPTTPCGITFTLSPTNGDYPSPPHLPLDPGSPPISPCSSNSGRLPALAPIISTPCSSADADDAGAAMGLPVRARRRSISRQEAIFVEPTGNSLENVSHEEVDNSNTKSSVDTADSLDEASTMATCGSPGAAGGSGASSSHHNAFVVRDIYLMVPDLKRDRAASVDSCFSKLSSNAKTEELQPSADGCFLTVPNINATRSRSVDIVLPTDEQARYKALSMTGSTVTYADGRTASASNSRRPIRIVPDWTENAVQGEHYWKPTSASGDLCCLNEE-----CIKSGQRMKCSACQLVAHHNCIPFVNEKSTLACKPTYRDVGIRQYREQTTTHHHWVHRKLEKGKCKQCGKFFPMKQAVQSKLFGSKEIVALACAWCHEIYHNKEACFNQAKIGEECRLGNYAPIIVPPSWIVKLPTKGNFKSSIRVSNKNNAASGSGGGGAGGGAGGGGGKSKKQTQRRQKGKEEKKEPRAFIVKPIPSPEVIPVIVFINPKSGGNQGHKLLGKFQHLLNPRQVFDLTQGGPKMGLDMFRKAPNLRVLACGGDGTVGWVLSVLDQIQPPLQPAPAVGVLPLGTGNDLARALGWGGGYTDEPIGKILREIGMSQCVLMDRWRVKVTPNDDVTDDHVDRSKPNVPLNVINNYFSFGVDAHIALEFHEAREAHPERFNSRLRNKMYYGQMGGKDLILRQYRNLSQWVTLECDGQDFTGKLRDAGCHAVLFLNIPSYGGGTHPWN---DSFGASKPSIDDGLMEVVGLTTYQLPMLQAGMHGTCICQCRKARIITKRTIPMQVDGEACRVKPSVIEIELLNKALMLSKRKHGRGDVQVNP-------------------------LEKMQLHILRVTMQQYEQYHYDKEMLRKLANKLGQIEIESQCDLEHVRNMLN----------------------TKFEESISYPKVSQDWCFIDSCTAEHYFRIDRAQEHLHYICDIAIDELYILDHEAATMPQTPDQERSFAAFSQRQAQNERRQMDQAQGRGPGST------DEDLQIGSKPIKVMKWKSPILEQTSDAILLAAQSGDLNMLRALHEQGYSLQSVNKNGQTALHFACKYNHRDIVKYIIASATRRLINMADKELGQTALHIAAEQNRRDICVMLVAAGAHLDTLDSGGNTPMMVAFNKNANEIATYLESKQGTQPVDGWLDD---", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . **: * . ... . * . : : : : : : :. : : .: * *.: :.* *: . :... : * . **:****:*:* * *. **:** *.** **. * **:.*::*.* ** : :* .: ****:*: . * *: . :******: ::***:**** * * * ******::*:**:: :*** :** :* * * ** :* :****:**:*: . :.*:: *.:. ::. : : ::* : :.: *.*::**:.** : *::**:********* *:* * *********:* **: .*:::**.****:***********:** **::* :.* *.*.************:*.*********:.*:* .: . * :***.::* . . : . ::****:*****:*.***::*****:***:**:****:****:*. . .*:: *. *:**: * : *** *:* *::: :.::***** * .** **. * . . *** :**:*:* .*. **.* ** : ***:. : * :::*:*****.**: *: :.*.* *:* *:.* *: . :* ::::::: :: :*:*: ::**: **. : :* : :..:**** * :: : : .. * ::* *.*:*: :*::::***::*****:: :*. **::*** : . . . : : : . ..*:* *. *** : ..* ** . : ** *.: .: ::*.:*: .. :::::: : *:**** ** *..* :* *: *** : *:** * : . ::*: ** : : . : ", "identical_positions": 335, "similar_positions": 289, "identity": "22.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120327-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P48550-1", "uniprot_id": "KCNJ6_RAT", "id": "P48550-1", "name": "G protein-activated inward rectifier potassium channel 2", "aln": "------------------------------MTMAKLTESMTNVLEG-DSMDQDVESPVAIHQPKLP-----------------------------------------------KQAR----------DDLPRHIS-RDRTKRKIQRYVRKDGKCNVHHGNVRETYR-YLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGDMDHIEDPSWTP----------CVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLP-KEELEIVVILEGMVEATGMTCQARSSYVTSEILWGYRFTPVLTL--EDGFYEVDYNSFHETHETSTPSLSAKELAELANR------------AELPLSWSVSSKLNQHAELETEEEEKN----PEELTERNGDVAN--LENESKV--------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P48542-1", "uniprot_id": "KCNJ6_MOUSE", "id": "P48542-1", "name": "G protein-activated inward rectifier potassium channel 2", "aln": "------------------------------MTMAKLTESMTNVLEG-DSMDQDVESPVAIHQPKLP-----------------------------------------------KQAR----------DDLPRHIS-RDRTKRKIQRYVRKDGKCNVHHGNVRETYR-YLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGDMDHIEDPSWTP----------CVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQSDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLP-KEELEIVVILEGIVEATGMTCQARSSYITSEILWGYRFTPVLTM--EDGFYEVDYNSFHETYETSTPSLSAKELAELANR------------AEVPLSWSVSSKLNQHAELETEEEEKN----PEELTERNGDVAN--LENESKV--------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P48051-1", "uniprot_id": "KCNJ6_HUMAN", "id": "P48051-1", "name": "G protein-activated inward rectifier potassium channel 2", "aln": "--------------------------------MAKLTESMTNVLEG-DSMDQDVESPVAIHQPKLP-----------------------------------------------KQAR----------DDLPRHIS-RDRTKRKIQRYVRKDGKCNVHHGNVRETYR-YLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGDMDHIEDPSWTP----------CVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLP-KEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTL--EDGFYEVDYNSFHETYETSTPSLSAKELAELASR------------AELPLSWSVSSKLNQHAELETEEEEKN----LEEQTERNGDVAN--LENESKV--------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GKY4-1", "uniprot_id": "A0AC58GKY4_DANRE", "id": "A0AC58GKY4-1", "name": "G protein-activated inward rectifier potassium channel 2", "aln": "--------------------------------------MQAQNLPE-VQMEQDVESTVTVRQPKLP-----------------------------------------------KQAR----------DDIPKPLQERERAKQKTQRYVRKDGKCNVHHGNVRETYR-YLTDIFTTLVDLKWRFNLFIFVLVYTVTWLFFGFMWWLIAYIRGDLEHIGDNQWTP----------CVNNLNGFVSAFLFSIETETTIGYGHRVITDKCPEGIVLLLVQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTNAVISMRDGRLCLMFRVGDLRNSHIVEASIRAKLIKSKQTKEGEFIPLNQTDINVGYDTGDDRLFLVSPLIICHEINQHSPFWEISREHMA-KEELEIVVILEGMVEATGMTCQARSSYVASEIKWGYRFTPVLTL--EDGFYEVDYNSFHEIYETNTPSCSARELAEMTAR------------ARLPLTWSVASKLSQ---LEPQEP-------PEELTERNGDVAN--MESESKV--------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4KH86-1", "uniprot_id": "A0A0B4KH86_DROME", "id": "A0A0B4KH86-1", "name": "", "aln": "---MPKMIVDKSELVGENAWAKLLPDEKDKAIIVKMNKSSSNNNDSKETTPLNVDQLVAASNPAVAGEQSAVCLEDTYKRTSTYASNINSTGGESSGSGTQLSRKESILGSFHRQIRRSIKAVSESPGPLTRYRQTRFSSRRVRKRVVFKHGECNVVQGNVAKRRRRYLQDIFTTLVDAQWRWTLLVFAASFVFSWAFFGFIWWIIAYAHNDLEYTNLKNQSPDLVANITHTVCVTQVSNMMSAFLYSVETQTTIGYGNRYVTEECPEAIFTMCIQCITGVFIQAFMVGIVFAKLSRPKKRAQTLLFSRNAVICHRDGVPCLMFRVGDMRKSHIIEAHVRAQIIRKKVTKEGEVLPFYQQELHIGADGGEDRLMFIWPTTIVHKIDRNSPLYMLSASDML-KERFEVVVMLEGVIESTGMTTQARSSYLPSEVLWGHRFVNVVSFRKETGEYEVDYTLFNNTYDVDTPLCSAKQLDELKSEYSKSAKCVNAPFADRTLSASLFQRIASAASVDHLDPASDESLDSGRLQIRSHSIPNGVLASELEPLNNNKHGASFTMGGLTITTTAPSIPNLSSINEKTNSGNSINSSNYSNNNSLSTLTGGGSAASGPGGGITIVAGSGNHGGAGGGGGGGGRHKSNPRRLSIKQDQLPIDSIC", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "B7YZX2-1", "uniprot_id": "B7YZX2_DROME", "id": "B7YZX2-1", "name": "", "aln": "MQSDASPLGAAATDSLTMHRSTSMPVKPKPLEQKPLLRSSEKETVNASDYYPESPGFVRRRRSKAAG----------------------------DHLETRSEQNPTFSFPYAHDWAGSTIELTPDLGSGPRTSS-SDGLRRSLNRVMEKNGKENVVFRRIPEKSWRYMRDLVTTLMELEWKYMLTLFLGSYFLSWLLFAALCYVVAYSHGDFIFDPVSGKRMG----EGVDPCIYGVHSWVAMIIYSVETQTTLGFGEKYASEECPETIFLFVMQMLSAALIEGCMVSVIYAKTARPARQLTKLKFSDKAVICYRDGRLCLLFRVCDPREQQSIESKIRVYIIVDKRTREGETIKSHVELKLE----GNGEQIILWPDVVCHVIDETSPLSQFTTAKLFNAAQFELYVSIVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYDAQNERYIVDYENFNRTISVDMPMTNPKN-------------------DHLKLEYRK----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : * .. . :: . .: . :: :* : *.*: ** .: : *: *:.***:: :*:: * :* : .:* :*. : :::** :.*: . *: : . :: :::*:**:**:*:* : :::*** *. : :* : . :::. **. ::.* ::* :: .* ** :***. *** **:*** * *:.: :*: :*. :* .* * *** : *:.. ::: * : * *:. **: :: .: .:*: * : * :*. :*::**:. *: ** **. :: : * *** *:. ... * ..:: * ", "identical_positions": 85, "similar_positions": 128, "identity": "12.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120328-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8C9H6-1", "uniprot_id": "STRP2_MOUSE", "id": "Q8C9H6-1", "name": "Striatin-interacting proteins 2", "aln": "------------------MDDPAAPGPAGSPANDNGNGNGNGNGNGNGGKGKPAVPK-----------GRETFRNQRRESEGS-------------------------VDCPTLEFEYGDSDGHAAELSELYSYTE-NLEFTTNRKCFEEDFRTQVQDTKEWLE-------LEEDAQKTYVMGLLDRLEVVSREKRLKVARAVLYLAQG----------------TFGECDSEVDVLHWSRYNCFLLYQMGTFSAFLELLHMEIDNSQ-ASSSALRKPAVSIADSTELRVLLSVMYLMVENIRLEREIDPCGWRTARETFRTELSFSTHNEEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQALKIQKRAELGLPPLAEDSIQVVKS-----MRAASPPSYTLDLGESQLAPPPSKLRGR----------------RG----SRRQLLTKQDSLDIYNERDLFKTEEPATEEEEESAADGERTLDGELDLLEQDPLVPPPPSQTPLS--TDRVAFPKGLPWAPKVRQ-------------KDIEHFLEMSRNKFIGFTLGQDTDTLVGLPRPIHESVKTLKQHKYISIADIQIKNEEELEKCPLSLGEEVVPETPSEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPVTVLQSMKLGIDVN---------------RHKEIIVKSISALLLLLLKHFKLNHIYQFEYVSQHLVFANCIPLILKFFNQNILSYITAKNSISVLDYPCCTIQDLPELTTESLEAG---DNSQFCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYDKP-----------QDSEFSPVDNCLQS----------------------------------VLG-----------------------QRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G7M4-1", "uniprot_id": "A0A8I6G7M4_RAT", "id": "A0A8I6G7M4-1", "name": "", "aln": "------------------MDDPAAPGPSGSPANDNGNGNGNGNGNGNGGKGKPAVPK-----------GREAFRNQRRESEGS-------------------------VDCPTLEFEYGDADGHAAELSELYSYTE-SLEFTTNRKCFEEDFKTQVQDTKEWLE-------LEEDAQKTYVMGLLDRLEVVSREQRLKVARAVLYLAQG----------------TFGECDSEVDVLHWSRYNCFLLYRMGTFSAFLELLHMEIDNSQ-ASSSALRKPAVSIADSTELRVLLSVMYLMVENIRLEREIDPCGWRTARETFRTELSFSTHNEEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQALKIQKRAELGLPPLAEDSIQVVKS-----MRAASPPSYTLDLGESQLAPPPSKLRGR----------------RG----SRRQLLTKQDSLDIYNERDLFKTEEPATEEEEESASDGERTLDGELDLLEQDPLVPPPPSQTPLS--ADRVSFPKGLPWAPKVRQ-------------KDIEHFLEMSRNKFIGFTLGQDTDTLVGLPRPIHESVKTLKQHKYISIADVQIKNEEELEKCPMSLGEEVIPETPSEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPATVLQSMKLGIDVN---------------RHKEIIVKSISALLLLLLKHFKLNHIYQFEYVAQHLVFANCIPLILKFFNQNILSYITAKNSISVLDYPCCTIQDLPELTTESLEAG---DNSQFCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYDKP-----------QDSEFSPVDNCLQS----------------------------------VLG-----------------------QRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9ULQ0-1", "uniprot_id": "STRP2_HUMAN", "id": "Q9ULQ0-1", "name": "Striatin-interacting protein 2", "aln": "------------------MEDPAAPGTGGPPANGNGNG---------GGKGKQAAPK-----------GREAFRSQRRESEGS-------------------------VDCPTLEFEYGDADGHAAELSELYSYTE-NLEFTNNRRCFEEDFKTQVQG-KEWLE-------LEEDAQKAYIMGLLDRLEVVSRERRLKVARAVLYLAQG----------------TFGECDSEVDVLHWSRYNCFLLYQMGTFSTFLELLHMEIDNSQ-ACSSALRKPAVSIADSTELRVLLSVMYLMVENIRLERETDPCGWRTARETFRTELSFSMHNEEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQTLKVQKRAELGLPPLAEDSIQVVKS-----MRAASPPSYTLDLGESQLAPPPSKLRGR----------------RG----SRRQLLTKQDSLDIYNERDLFKTEEPATEEEEESAGDGERTLDGELDLLEQDPLVPPPPSQAPLS--AERVAFPKGLPWAPKVRQ-------------KDIEHFLEMSRNKFIGFTLGQDTDTLVGLPRPIHESVKTLKQHKYISIADVQIKNEEELEKCPMSLGEEVVPETPCEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVN---------------RHKEIIVKSISTLLLLLLKHFKLNHIYQFEYVSQHLVFANCIPLILKFFNQNILSYITAKNSISVLDYPCCTIQDLPELTTESLEAG---DNSQFCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKLQTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYDRP-----------QDSEFSPVDNCLQS----------------------------------VLG-----------------------QRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PI62-1", "uniprot_id": "A0A8M9PI62_DANRE", "id": "A0A8M9PI62-1", "name": "", "aln": "---------------------MQQTDDMEVPLIHDSNS-----------NTHTCLPQ-----------ERDGFHQQK-DSEGS-------------------------MESPNLEFEYGDTDSFTAELSELYSYTE-EPEFSLNRDYFEEDFKNHVKG-RRWME-------LSVEEQRAYVMRLLDALEVTDRDKRLKVARAILYLAQG----------------VFDECDTETDVLYWSRHNVFLLYDMGIFTALLELLSMEIDNNQ-ACSSAVRKPAISLADSTELRVLLSIMYLMVETIRVEMESDSPERKAAREAFKMELGSPLYNGEPFALLLFTMVTKFCSMNAPHFPMKKVLLLLWKTILFTLGGFEELQEMKVRMRDHLNLPPLPEDSIKVVRN-----MRAASPPASAMELIEQQQQQKRGRRSRRSAFVDSL---------EGDSPYAKKQPLVKQDSLDTYNERDPFKNDD--ARDEEDDPEDVDSGIEGEVDPLDRDVIIQPPPPPPPLRPPTERMSFPKGLPWAPKVRE-------------KDIEHFLETSRNKFIGFTLGNDIDTLVGLPRPIHESVKTLKLHKYVSIAEVQIKREDELQQCPMTMGEEEVEETPTEILYLGMLPSLSQYVIALLKLLLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVN---------------RHKEIIVKAISALLLLLLKHFKLNHIYQFEYVAQHLVFANCIPLILKFFNQNIMSYISAKNSICALDFPHCAVHEMPELTAESLEAG---DSNQFCWRNLFSCINLLRILNKITKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDIDARPWDFQAEECALRESIEKFNTRRYDKN-----------QNSEFAPVDNCLQS----------------------------------VLG-----------------------QRVDLPEDFHYSYEMWLEREVFSQPIQWEGLLQAQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IRD5-1", "uniprot_id": "Q8IRD5_DROME", "id": "Q8IRD5-1", "name": "", "aln": "---------MAWKQKNKLLFDTCKNQLSCGAVNARSSMMQSIQSRINVLNTIAASSKRI---------ERASVDTDTHDADAN-------------------------CDGPDLDFVYADVDGYQNEIAELYSYTE-FSEFQMNVKAFEDQMELYDLP-PNWQK-------QDSASQRGIVMKLVDQLEVSDRSFRMQAARCILYLAQG----------------CWAEVQSDEEQHQITRDNVLVLYQLGVFASFIDLLNMEIESACSPDIVAVKITNVTLVDSTDIRVILSVLYIITETIRDEKEKGSEDYRELADSFVQEINSPLPDGELLAVKLLGMITRFCSGAAPQFPMKKVVLLLWKVSLLGLGGMDVLKNLKNEYRLKVGLEPITEDTLEVTKC-----MRASSPPATATDILENQYPKRNFKRSLMK---------------QRFLDEPEQIDMEMGGNEGQNNANNGSGNGGNGEEELSQYYRPYDDPSSSASTTSTANPNNQPSLTQPPAA--VPPVQITARLPWTPKVRQ-------------KDIDQFLDISRNKFIGYSLIGDHESLAGLPQPIHEGFKTLQRHMYMSLADVQIKKEEDIARNPISTHEDEIKLTPAEVLYQAILPNLPQYMIALLKVLLAASPTSKSKTESINIMADVLPRKMPLTATQSTKLTVDIG---------------RHKEIIVKAVSAIILLYLKHFKINHVYQFEFMSQHLVFANCIPLVLKFFNQTITEYVNTKNSIPLLDFPSCVIGEQPDLSGDSFVYGGEMSDKSYSWRNVFSCINLLRILNKLIKWKHSRVMMLVVFKSAPILKKTLKVRHAMMQLYVLKLLKMQTKYLGRQWRKSNMKTMSAIYAKVRHRLNDDWAFGNDLESRPWDFQAEECTLRACVDRFNLRRYPEATQKCGNNGTAAQNAENAQQSNMMAGNNGCGNNGDANGYGNNGGGGNGGHNQQQQLNDYGVEGGFPSDEILTHSDFAFFGHSGWWDRKVELTDYFKANYAVWLEEEVYNSQTDWDAL----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53917-1", "uniprot_id": "FAR11_YEAST", "id": "P53917-1", "name": "Factor arrest protein 11", "aln": "MNASGRSHSKGPIIRSVSLEDLKRNSSFKGNLKYKDEVTSHKEPQVGTLSNEELLKDLDNMLRGKLNMGRNSFHADKRNKSDGNISALTFKARSGLEGDIRTIDIQQDSSDENDNFKFSDDGVNKDRNNEKDNNTDNAVEFQDDAEEAEEENEDESFANVDELDGFDLNKVSDGKHVPINEKGEVDYNMPVDKEFQKSLDQCAASLEERSSAPYALQRAVDWELKMFYSLEDELSEWFCSSDYMHFGQTQTLFKQKITQPQLFFDDENYAASVVECLIEDIPNSLASNLLALSYISMGCFAFTNSKSEHTKIIRRNNLMLVPHIQEIVHAFKKIAISCRDDNRNLKKQTILLFHSSTILYFICSICIEGRGENPEAVNVVIDAFEKTDLLEFLTKYIENWRWNSRLAMRIRNMISLLFKLIVLQFGDSSVYKQTKSSIYNLHGLTYPSKHPEKLSISPLHYQAFREDITSRFPDYNMPSSGLPKDVDKSESLSQFLEIPRPKSKNPLNMALIVPEKHIATPAPSPPSSPQLMHLGEGPRPRKSFQTNMAYPCLYPSDNEGSEDDTLEDRIDLNIERKPDNDIVIPFSTEEAARILSESLEIKLSTKQLWYERDLFMITERGWKQQLENEPYDYAALNHDANSSKEEKSAICIMQRIDKYYKSCLSSFNSLVFVLLQTMESSLTNNFHRKSEVSDKNLLNMLTPQLEIVRAKELSLKSAAGILHALLKWFKLSHILKFEHLAVVIHDSRYINTCASILSK--YSEVYPERVFNKYVQTPNSFWKECSLSNESYRESYSVDDSGEVDTEIMPSFAYLLRILRKVTGNKTQRLKELPLSIGILFKRYYRLFNLDMYHPILKITRELTPFKNKRWKSEHMELISGVYLYEKLELTDNWVTGKDISGELSDACGQEIALRALLQFYNFQHYEIS------------------------------------------------------------------------------------------MEDLGYGHRNSSSQDLLNKESEYLNI----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . . * . : : . . . :* :.* . . * . *: ** : *:: . . . :* .:. : . :. * : : . : : . : . * : : ::. . . . :. : ** : : : . . . : : .: : :*: .: . * ..:: :: . : * : . .* : . :: : ** . : .: * . . : . . : . : .: * .. * *: *: .* : : : :. *. .: . :. :* . .*. : *. :.:: *: * :: . :: : * : . .: : : :: *: .*:* :. ** . * : :. : ::. * **: :*: : :: ** **:.*: :**.:: : :. * .::.: . : .:. : . . . .*: :* . ... :::..: * : : . :::: : : :. . ::*: :: : : :**: : * : .::*:..:*: :*.:* : .:.*:*. *:*:... * .:* :** :: :* ::* : : .: ..:: .. : : ", "identical_positions": 71, "similar_positions": 258, "identity": "6.77%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120328-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91XA5-1", "uniprot_id": "SNPC2_MOUSE", "id": "Q91XA5-1", "name": "snRNA-activating protein complex subunit 2", "aln": "MKPPQRRRRVPARYVGEATGPTAWSPR------EMRHLLRLLQARRGQ----PEPDAAELAQELRGRSEAEICRFIQQLKGRVVREAIQKMQPGGREGPRHQGTPLPAPVEVWMDLAEKLTGPMEEALTAAFSQVLTIAAAEPLSLLHSRPGKPTKARGKALVFLSNQDGQKDPASEGSGPVPMTAADPTREASVSDPKASGANP--------ETSGLASEVTVPDPDAPTKSLAGSSTERDLAVD----------------------------------------FEKIYKYLSFSSRGGHGPELSAAESAVVLNLLMALPEELSHLPCTALLEHMTKTYAQLMAPQTALPGEKRPRPGTEDGGTGSTGPEEPDQASPQASEPIEPRLAWKAVGICPLNPFLVPLGLVSQAPSPSR-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13487-1", "uniprot_id": "SNPC2_HUMAN", "id": "Q13487-1", "name": "snRNA-activating protein complex subunit 2", "aln": "MKPPPRRRAAPARYLGEVTGPATWSAR------EKRQLVRLLQARQGQ----PEPDATELARELRGRSEAEIRVFLQQLKGRVAREAIQKVHPGGLQGPRRREAQPPAPIEVWTDLAEKITGPLEEALAVAFSQVLTIAATEPVTLLHSKPPKPTQARGKP-LLLSAPGGQEDPAP---------------EIPSSAPAAPSSAP--------RTP-------DPAPEKPSESSAGPSTEEDFAVD----------------------------------------FEKIYKYLSSVSRSGRSPELSAAESAVVLDLLMSLPEELPLLPCTALVEHMTETYLRLTAPQP-IPAGGSLGPAAEGDGAGSKAPEETPPATEKA-EHSELKSPWQAAGICPLNPFLVPLELLGRAATPAR-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5L3-1", "uniprot_id": "A0ACD6B5L3_DANRE", "id": "A0ACD6B5L3-1", "name": "", "aln": "MKPPRRQRTVPSRFHKTPEQEQIDSARSLCKGWNRKDLHSFLQALKQQQDFESEIDLTEIQKKIPQRSLKQIENLINKVKLRVLQKVFKQVKS-----QRKKERKAKVPIETWGEMVQKISTSHGKTISAAFSQMLVVAATEPCSLMHSEPPHPVTQTPVFSRLYPAHTPNTPSRPTTSGVSPSSSVSTASAVSFIRPDSSSSAAGHIGKSDTVSSSLHQEPVMPEASTPTSSSSQSRSEAEAAVSSPVSSRPSPSTSSNKPSPISLELLGHDYPCKPRIMKSVVNFDKIYAYLGDMDSKTCSSALSSMECAVLLDLLMCLPEELPLLDCKGLQHHLLQLHSQLSKPTVKPESYSNGPLSGEANSSTSVQKLCAAAGSSEKHGPVKDSDDWASAGICPLNPLSVPVTLLKRKSVDCDK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**** *:* .*:*: *.* : :.* :*** : * .* * :*: ::: ** :* :::::* ** ::.:::::. *:: .*:*.* ::.:*:: . ::::.****:*.:**:** :*:**.* :*. : . : . . . * :..: . :. * .. *:.* : . :* : **. *:*** **. . .. **: *.**:*:***.*****. * *..* .*: : : :* * . . * ..: * . .: : : * :.*******: **: *: : . . ", "identical_positions": 89, "similar_positions": 115, "identity": "21.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120328-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GH02-1", "uniprot_id": "A0A8I6GH02_RAT", "id": "A0A8I6GH02-1", "name": "", "aln": "--------MVISLRAGCRAALSLWILSSFICRAWTAPSSFQKCDEPLVSGLPHVSFSSSSSLSSSYAPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQ-DGNIWAFPGNVNSDSVVRHDLQHAVVARYVRIVPLDWNGEGHIGLRAEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLKDVIALKFKTSESEGVLLHGEGQQGDYITLELKKAKLVFSLNLGSNQLGPIYGHTSVTSGSLLDDHHWHSVLIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSNRKNFKGCMESINYNGVNITDLARRKKLEPS----NVGNLSFACVEPYTVPVFFN-ATSYLEVPGRLNQDLFSVSFQFRTWNPSGLLLFSHFADNLGNVEIDLVESKVGVHINTTQTKTSQIDISSGSGLNDGQWHEVRFLAKENFAVLTIDGDEASAVRTNSPLQVKTGERYYFGGFLNHMNNASHSALQPSFQGCMQLIQVDDQLVNLYEVAQRK-PGSFANVTIDMCAIIDRCVPNHCEHGGKCSQTWDSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSN--YYWIDPDGSGPLGPLKVYCNMTED-KVWTIVSHDLQMQTTVVGYNPEKYSVTQLIYSASMDQISAITSSAEYCEQYVSYFCKMSRLLNTPDGS----PYTWWVGKANEKHYYWGGSEPGIQKCACGIERNCTDPKYYCNCDADYKQWRKDAGFLSYKDHLPVSQVVVGDTDRQGSE--AKLSVGPLRCQGDRNYWNAASFPNPSSYLHFSTFQGETSADISFYFKTLIPRGVFLENLGNTDFIKLELKSSTEVSFSFDVGNGPVEIVVRSPSPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVGGAGGQ-QGFLGCIRSLRMNGVTLDLEERAK-VTSGFKSGCSGHCTSYGANCENGGKCIEKYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQALTVTARDTGSRAENSADQQQHLAPDLAQEQIHFSFSTTKAPCILLYVSS-LTTDFLAVLVKPTGNLQIRYNLGGTREPFNIDVDHRNMANGQPHSVNITRHEKTIILKLDHYPAAGY--HLPSSSDTIFNSPKSLFLGKVIETGKID-QEIHKYNTPGFTGCLSRVQFNHIAPLKAALRQTNASAHVHIQGDLVESNCGASPLTLSPMSSATDPWHLDHLDSASADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIR-YMFRHKGTYHTNEAKGAESAESADAAIMNNDPNFTETIDESKKEWLI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9CPW0-1", "uniprot_id": "CNTP2_MOUSE", "id": "Q9CPW0-1", "name": "Contactin-associated protein-like 2", "aln": "--------MVMSLRAGYRAALSLWILSSFICRAWTAPSTFQKCDEPLISGLPHVSFSSSSSLSSSYAPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQ-DGNIWAFPGNINSDSVVRHDLQHAVVARYVRIVPLDWNGEGHIGLRAEVYGCAYWADVINFDGHGVLPYRFRNKKMKTLKDVIALKFKTSESEGVLLHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVTSGSLLDDHHWHSVLIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSNRKNFKGCMESINYNGVNITDLARRKKLGPS----NMGNLSFSCVEPYTVPVFFN-ATSYLEVPGRLNQDLFSVSFQFRTWNPSGLLLFSHFADNLGNVEIDLVESKVGVHINNTQTKTSQIDISSGSGLNDGQWHEVRFLAKENFAVLTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNHMNNASYSALQPSFQGCMQLIQVDDQLVNLYEVAQRK-PGSFANVTIDMCAIIDRCVPNHCEHGGKCSQTWDSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSN--YYWIDPDGSGPLGPLKVYCNMTED-KVWTIVSHDLQMQTTVVGYNPEKYSVTQLIYSASMDQISAITSSAEYCEQYVSYFCRMSRLLNTPDGS----PYTWWVGKANEKHYYWGGSEPGIQKCACGIERNCTDPKYYCNCDADYKQWRKDAGFLSYKDHLPVSQVVVGDTDRQGSE--AKLSVGPLRCQGDRNYWNAASFPNPSSYLHFSTFQGETSADISFYFKTLIPRGVFLENLGNTDFIKLELKSATEVSFSFDVGNGPVEIVVRSPSPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVGGAGGQ-QGFLGCIRSLRMNGVTLDLEERAK-VTSGFKSGCSGHCTSYGANCENGGKCIEKYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAPAVTARDTGSRAENSADQQQHLAPDLAQEQIHFSFSTTKAPCILLYVSS-LTTDFLAVLVKPTGNLQIRYNLGGTREPFNIDVDHRNMANGQPHSVNITRHERTIILKLDHYPAVGY--HLPSSSDTLFNSPKSLFLGKVIETGKID-QEIHKYNTPGFTGCLSRVQFNHIAPLKAALRQTNASAHVHIQGELVESNCGASPLTLSPMSSATDPWHLDHLDSASADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIR-YMFRHKGTYHTNEAKGAESAESADAAIMNNDPNFTETIDESKKEWLI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UHC6-1", "uniprot_id": "CNTP2_HUMAN", "id": "Q9UHC6-1", "name": "Contactin-associated protein-like 2", "aln": "--------MQAAPRAGCGAALLLWIVSSCLCRAWTAPSTSQKCDEPLVSGLPHVAFSSSSSISGSYSPGYAKINKRGGAGGWSPSDSDHYQWLQVDFGNRKQISAIATQGRYSSSDWVTQYRMLYSDTGRNWKPYHQ-DGNIWAFPGNINSDGVVRHELQHPIIARYVRIVPLDWNGEGRIGLRIEVYGCSYWADVINFDGHVVLPYRFRNKKMKTLKDVIALNFKTSESEGVILHGEGQQGDYITLELKKAKLVLSLNLGSNQLGPIYGHTSVMTGSLLDDHHWHSVVIERQGRSINLTLDRSMQHFRTNGEFDYLDLDYEITFGGIPFSGKPSSSSRKNFKGCMESINYNGVNITDLARRKKLEPS----NVGNLSFSCVEPYTVPVFFN-ATSYLEVPGRLNQDLFSVSFQFRTWNPNGLLVFSHFADNLGNVEIDLTESKVGVHINITQTKMSQIDISSGSGLNDGQWHEVRFLAKENFAILTIDGDEASAVRTNSPLQVKTGEKYFFGGFLNQMNNSSHSVLQPSFQGCMQLIQVDDQLVNLYEVAQRK-PGSFANVSIDMCAIIDRCVPNHCEHGGKCSQTWDSFKCTCDETGYSGATCHNSIYEPSCEAYKHLGQTSN--YYWIDPDGSGPLGPLKVYCNMTED-KVWTIVSHDLQMQTPVVGYNPEKYSVTQLVYSASMDQISAITDSAEYCEQYVSYFCKMSRLLNTPDGS----PYTWWVGKANEKHYYWGGSGPGIQKCACGIERNCTDPKYYCNCDADYKQWRKDAGFLSYKDHLPVSQVVVGDTDRQGSE--AKLSVGPLRCQGDRNYWNAASFPNPSSYLHFSTFQGETSADISFYFKTLTPWGVFLENMGKEDFIKLELKSATEVSFSFDVGNGPVEIVVRSPTPLNDDQWHRVTAERNVKQASLQVDRLPQQIRKAPTEGHTRLELYSQLFVGGAGGQ-QGFLGCIRSLRMNGVTLDLEERAK-VTSGFISGCSGHCTSYGTNCENGGKCLERYHGYSCDCSNTAYDGTFCNKDVGAFFEEGMWLRYNFQAPATNARDSSSRVDNAPDQQ-NSHPDLAQEEIRFSFSTTKAPCILLYISS-FTTDFLAVLVKPTGSLQIRYNLGGTREPYNIDVDHRNMANGQPHSVNITRHEKTIFLKLDHYPSVSY--HLPSSSDTLFNSPKSLFLGKVIETGKID-QEIHKYNTPGFTGCLSRVQFNQIAPLKAALRQTNASAHVHIQGELVESNCGASPLTLSPMSSATDPWHLDHLDSASADFPYNPGQGQAIRNGVNRNSAIIGGVIAVVIFTILCTLVFLIR-YMFRHKGTYHTNEAKGAESAESADAAIMNNDPNFTETIDESKKEWLI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TGU6-1", "uniprot_id": "A0AB32TGU6_DANRE", "id": "A0AB32TGU6-1", "name": "", "aln": "----------MQPPAGIGLKLLLWILS-HISISQAASPSSQKCDEALVTQLLHNAFTSSSVFASSYVPGYAKLNKRGGAGGWSPLDSDHYQWLQVDLGSRKQVTAVATQGRYSSSDWTTRYRLLYSDTGRNWKPYHQ-DGNIWAFAGNSNTESVVRHDLQNPVVARYLRIIPLDWSEEGRIGLRFEIYGCPYWADVINFDGQGVISYRFKMKKMKILKDVIALKFKTSESEGVILHGEGQQGDYITLELRRGRLLLQINLGSNQHGSILGHTSVTSGSLLDDHHWHSVVIERYRRNVNFTLDQHTQHFRTNGEFDHLDLDYELTFGGMPYSGKPVIGGRRNFKGCMESINYNGENITDLARRKKLDTS----SFRNLTFSCVDTHTFPVFFN-GTSFLQLPGRRDHNMVSVGFQFRSWNPSGLLLFSSLAD--GMLELALNDGKVTAHINVTQQKNMRVDIASGSGLNDGEWHDVRFLAKENFAMLTIDGDEASAVRTNSPVLITTGSTYHFGGYFLRTR---ASPIQRSFQGCMQLIQVDDQLADLTAVEQGR-IGAFENVSLDMCAIIDRCMPNHCEHGGRCSQTWDSFTCTCDGTGYTGATCHTSVYEQSCEAYKHLGRSSD--AYWIDPDGSGPLGPFKVICNMTED-KVWTTVVNNLPAQTAVTGSSRERRTVLQLNYSASMEQVTAITNSAEHCEQHVSYACRMSRLLNTPDGT----PYTWWVGRGNEKHFYWGGSAPGIQKCACGIERNCSDSKYYCNCDADQKQWRDDSGLLVYKDHLPVSQVAVGDTNRPGSE--AKLTVGPLRCHGDRNYWNAASFNTPSSYLHFSTFQGETSADISFYFKTSAPYGVFLENLGNTDFIRLELKSPMVVSFSFDVGNGPVELNVHSPTPLNDDQWHRVSAERNTKEAILQLDQKYKEIRPAPTQGHTRLELYSQLYVGAAGGQ-RGFLGCIRSLKMNGVTLDLEERAK-VTPGVKPGCSGHCTSFGMYCRNGGKCVEKYNGYSCDCTTTAYDGPFCSKDVGGFFEAGTLVKYNLVPEVLAAAS--SLDEKSIIHNLPVETNLTHEDLTFSFSTSTSPSLLVYVSS-KTQDYMAVVLRHNGTLQLRYSLGGLREPFTIDIDQRNLANGQPHTVNISRVERDIEVQLDHYPAVTY--SLPEASDTQFTLVKSLFLGKVFETGYIDPVLIEKYNTPGFVGCLSRVQFNSIAPLKAALRSR-GSVSVSHQGKLVESNCGASPLTIPPMSAATDPWHLD----AGADFPFN--EERVIPDGVNRNSAIIGGIIAVVIFTILCTLVFLIR-YMFRHKGTYHTNEAKGGESSESADAAIIGTEANFTETIDESKKEWFI", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q94887-1", "uniprot_id": "NRX4_DROME", "id": "Q94887-1", "name": "Neurexin-4", "aln": "MRPPRSNTKAAFSSLQFGLLCLLLLVNNGIKSVQADAFTDYFSDYDCNQPLMERAVLTATSSLTERGPDKARLN---GNAAWTPVENTYNHFLTLDLGDPRMVRKIATMGRMHTDEFVTEYIVQYSDDGEFWRSYVNPTSEPQMFKGNSDGNSIHYNVFEVPIIAQWVRINPTRWHDR--ISMRVELYGCDYISENLYFNGTGLVRYDLRREPITSTKESIRFRFKTAFANGVMMYSRGTQGDYYALQLKDNKMVLNLDLGSR------VMTSLSVGSLLDDNVWHDVVISRNQRDIIFSVDRVIVRGRIQGEFTRLNLNRELYLGGVPNVQEG-LIVQQNFSGCLENIYFNSTNFIRVMKDSTELGEGYLFTRVNTIYACPSPPIYPVTFTTRSSFVRLKGYENSQRLNVSFYFRTYEETGVMLHHDFYSG-GYLKVFLEFGKVKIDLKVKDKARIILDN-YDDQFNDGKWHSFVISIEKNRLILNID---QRPMTTTKSMQVATGAQYYIAG----------GKDKNGFVGCMRLISVDGNYKLPQDWVKGEEVCCGDDVVVDACQMIDRCNPNPCQHKGLCHQNSREFFCDCGHTGYAGAVCHTSNNPLSCLALKNVQHVQQRVNLNLDVDGSGPLEPFPVTCEFYSDGRVITTLSHSQEHTTTVDGFQEPGSFEQSIMYDANQLQIEALLNRSHSCWQRLSYSCRSSRLFNSPSEAGNFRPFSWWISRHNQPMDYWAGALPGSRKCECGILGKCHDPTKWCNCDSNSLEWMEDGGDIREKEYLPVRAVKFGDTGTPLDEKMGRYTLGPLRCEGDDLFSNVVTFRIADASINLPPFDMGHSGDIYLEFRTTQENSVIFHATGPTDYIKLSLNGGNKLQFQYQAGSGPLGVNVGTSYHLNDNNWHTVSVERNRKEARLVVDGSIKAEVREPPGPVRALHLTSDLVIGATTEYRDGYVGCIRALLLNGKMVDLKEYSKRGLYGISTGCVGRCESN--PCLNNGTCIERYDGYSCDCRWSAFKGPICADEIGVNLRSSSIIRYEFEGSFR---------------------STIAENIRVGFTTTIPKGFLLGFSSNLTGEYLTIQISNSGHLRCVFDFGFERQEIIFPKKHFGLGQYHDMHFMRKNGGSTVVLKVDNYEPVEYNFDIKASADAQFNNIQYMYIGK------------NESMTDGFVGCVSRVQFDDIYPLKLMFQQNPPKNVKSLGTQLTEDFCGVEPVTHPPIEIETRPPPLVD--------------EEKLRKAYNEVDSVLLACLLVILFLLLILMFFLIGRYLHRHKGDYLTHEDQGADGADDPDDAVLHS---TTGHQVRKRTEIFI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ::. : : . : .* * . :. ::: . *. *::* * ..*:* :. : ::* :*:*. : : :** ** :.::.*.* : *** *. *:.* : .: * ** : :.: : :: .::*:::** * * . *.:* *:*** * :: : *:* :: * :: : :. *: * :.***: ::**:::..* **** :*:*: ::::.::***. **: ******: **.*:*.* *.: :::*: : * :*** *:*: *: :**:* : ::**.**:*.* :*. *: : : .. . . * ::* .. ** *. :*::.: * : : ..*.* **::: .*:::. : . * ::: * .** .:: .: :* .. :***:**.. : ::* :*.** .: *...: : ** *.:.* . : .* ***:**.**.: : . . :* :* * :**** ** *:* * * *. .* * *. ***:**.**.* ** * *:: : .: :* ****** *: * *:: .* :* * : :. *.* * . .: *.*. *: *: . :. * * :** *: ***:*:*. : *::**:.: *: **.*: ** :** *** :* *.. :****:: :* .*.* : *::*** * .***. .* .: ::*****.** : *..:* ..: :::..*: *.** : *:* .*::. * *:*:*.*:. :.*.::.*.**: : * :. ***::** *:.*** *:* * :* : *. *.* *:* :*.: *::****:* :** :**:* :* *. .** *:* * * *.*.*:*:*.****** :*:.*.:* .::* :. . ::*:: . *:: ..*:*: . :*: .** * ::::: : .* *: :.:* *: : .: .:.: : . .. : :::*:* .. * : ::*: *. : :::** .: * **.**:*****: * *** ::. . .*.*. **..*:* .*:. * * * . : .. *. .::: . : *::* :* :.*** *:.**** * *:* :*.:.::..* *:: . * ..:.* :*", "identical_positions": 365, "similar_positions": 446, "identity": "26.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120329-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35119-1", "uniprot_id": "TRPC4_RAT", "id": "O35119-1", "name": "Short transient receptor potential channel 4", "aln": "---------MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHK--KPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNY--RDDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSD------------------LNRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYS---------ALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLSCKGIR-------CEKQNN--------AFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTDFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLVKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIREAKTEEGLTEENVKELKQDISSFRFEVLGLLRGSKLSTIQSANAASSAS---------------------------------------------------------------SADSDEKSHSEGNGKDKRKNLSLFD-----------------------LTTLIHPR-SAVIASERHNLSNGSALVVQEPPREK-------------------------------QRKVNFVADIKNFG-----------------------LFHRRSKQNAAEQNANQIF-----SVSEEITRQQAAGALERNIQLESKGLASRGDRSIPGLNEQCVLVDHRERNTDTLGLQVGKRVCSSFKSEKVVVEDTVPIIPKEK-----------HAQE----------------------------EDSSIDYDLSPTDTVAHEDYVTTRL----------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9QUQ5-1", "uniprot_id": "TRPC4_MOUSE", "id": "Q9QUQ5-1", "name": "Short transient receptor potential channel 4", "aln": "---------MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHK--KPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNY--RDDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSD------------------LNRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYS---------ALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLSCKGIR-------CEKQNN--------AFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLVKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIREAKTEEGLTEENVKELKQDISSFRFEVLGLLRGSKLSTIQSANAAS------------------------------------------------------------------SADSDEKSQSEGNGKDKRKNLSLFD-----------------------LTTLIHPR-SAAIASERHNLSNGSALVVQEPPREK-------------------------------QRKVNFVADIKNFG-----------------------LFHRRSKQNAAEQNANQIF-----SVSEEITRQQAAGALERNIELESKGLASRGDRSIPGLNEQCVLVDHRERNTDTLGLQVGKRVCSTFKSEKVVVEDTVPIIPKEK-----------HAHE----------------------------EDSSIDYDLSPTDTAAHEDYVTTRL----------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UBN4-1", "uniprot_id": "TRPC4_HUMAN", "id": "Q9UBN4-1", "name": "Short transient receptor potential channel 4", "aln": "---------MAQFYYKRNVNAPYRDRIPLRIVRAESELSPSEKAYLNAVEKGDYASVKKSLEEAEIYFKININCIDPLGRTALLIAIENENLELIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHK--KPSGEKQVPPILLDKQFSEFTPDITPIILAAHTNNYEIIKLLVQKGVSVPRPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKSEYEELSRQCKQFAKDLLDQTRSSRELEIILNY--RDDNSLIEEQSGNDLARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAVKMVTCFIIGLLFPVFSVCYLIAPKSPLGLFIRKPFIKFICHTASYLTFLFLLLLASQHIDRSD------------------LNRQGPPPTIVEWMILPWVLGFIWGEIKQMWDGGLQDYIHDWWNLMDFVMNSLYLATISLKIVAFVKYS---------ALNPRESWDMWHPTLVAEALFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYEETKGLTCKGIR-------CEKQNN--------AFSTLFETLQSLFWSIFGLINLYVTNVKAQHEFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQLIADHADIEWKFARTKLWMSYFEEGGTLPTPFNVIPSPKSLWYLIKWIWTHLCKKKMRRKPESFGTIGRRAADNLRRHHQYQEVMRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRFEVLGLLRGSKLSTIQSANASKESSN--------------------------------------------------------------SADSDEKSDSEGNSKDKKKNFSLFD-----------------------LTTLIHPR-SAAIASERHNISNGSALVVQEPPREK-------------------------------QRKVNFVTDIKNFG-----------------------LFHRRSKQNAAEQNANQIF-----SVSEEVARQQAAGPLERNIQLESRGLASRGDLSIPGLSEQCVLVDHRERNTDTLGLQVGKRVCP-FKSEKVVVEDTVPIIPKEK-----------HAKE----------------------------EDSSIDYDLNLPDTVTHEDYVTTRL----------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IM91-1", "uniprot_id": "A0A0R4IM91_DANRE", "id": "A0A0R4IM91-1", "name": "", "aln": "---------MSQLYFRRTDNSSYRDRIPLRIVRAESELSTQEKSYLSAVEKGDYASVKLALEEAEIYFKININCIDPLGRTALLIAIENENLEIIELLLSFNVYVGDALLHAIRKEVVGAVELLLNHK--KPSGEKQVPPILLDKQFSDFTPDITPIILAAHTNNYEIIKMLVQKGVSVPQPHEVRCNCVECVSSSDVDSLRHSRSRLNIYKALASPSLIALSSEDPFLTAFQLSWELQELSKVENEFKAEYEELSHQCKHFAKDLLDQTRSSRELELILNF--RDDMNLLQDEANNELARLKLAIKYRQKEFVAQPNCQQLLASRWYDEFPGWRRRHWAGKLITCVFIGLMFPLLSLCYLVAPKSRYGLFIRKPFIKFICHTASYLTFLFLLLLASQHIVSNN------------------PDRQGPKPTTVEWMILPWVLGFIWTEIKQMWDGGFQDYIHDWWNLMDFVMNSLYLATISLKIVAYVKYS---------GCKPRDTWEMWHPTLVAEAVFAIANIFSSLRLISLFTANSHLGPLQISLGRMLLDILKFLFIYCLVLLAFANGLNQLYFYYENSEGMTCKGIR-------CERQNN--------AFSTLFETLQSLFWSIFGLISLYVTNVKADHKFTEFVGATMFGTYNVISLVVLLNMLIAMMNNSYQHIADHADIEWKFARTKLWMSYFEEGGTLPPPFNIIPSPKSICYLITWIKVHVFKRRSKRK-ETFGTLGRRAAENVRLNHQYQEVLRNLVKRYVAAMIRDAKTEEGLTEENFKELKQDISSFRYEVIGMMKGNRKSTRANKSDTSAS----------------------------------------------------------------DVSHPEGSLQYSSALKQNSKLHLYD-----------------------VTTALQQQNSEEAKASLGCLANGSAVVLTEPILKD-------------------------------KARSDFPKDFTDFG-----------------------LFPKK-------QNPNKIY-----SLAEEATESDPD---ILDWGKEDKPLAGKVEQDVN--ESKCLMEED----------------------ERVLEEQEMEHIAS------------------------------------------------------------SHEH----------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJJ7-1", "uniprot_id": "TRPG_DROME", "id": "Q9VJJ7-1", "name": "Transient receptor potential-gamma protein", "aln": "---------------------MMEEENTIRPHQEIRQLTLEEKKFLLAVERGDMAGTRRMLQKAQDTEYINVNCVDPLGRTALLMAIDNENLEMVELLINYNVDTKDALLHSISEEFVEAVEVLLDHENVTFHSEGNHSWESASEDTSTFTPDITPLILAAHRDNYEIIKILLDRGAVLPMPHDVRCGCDECVQSRQEDSLRHSRSRINAYRALASPSLIALSSKDPILTAFELSWELRRLSFLEHEFKNEYQELRKQCQDFATALLDHTRTSHELEILLNH--DPTGPVYEHGERMHLNRLKLAIKLRQKKFVAHSNVQQLLASIWYEGLPGFRRKNMALQAVDIIRIGIMFPIFSLAYILAPYSSIGQTMRKPFIKFICHSASYFTFLFLLMLASQRIETFIGGWFFADSSGMLNTMEELPTKRGAKPTFIEWLILAWVSGLIWSEVKQLWDVGLQEYLNDMWNVIDFVTNSLYVATVALRVVSFFQVQKEMIYNSHATDLPRERWDAWDPMLISEGLFSAANIFSSLKLVYIFSVNPHLGPLQVSLSRMVMDIMKFFFLYVLVLFAFGSGLNQLLWYYADLEKKRCPEVSPMSALLNMNGTNDPNACIVWRRFSNLFETTQTLFWAVFGLIDLDSFELDGIKIFTRFWGMLMFGTYSVINIVVLLNLLIAMMNHSYQLISERADVEWKFARSKLWISYFEEGGTCPPPFNIIPTPKSIWYAIKWMRRVFCSGSSAARREHLKTIRRKAQQASDRDFKYQQIMRNLVRRYVTVEQRKAE-SQGVTEDDVNEIKQDISAFRCELVEILKNSGMDTNVTAGQGGGGGGKKNRQKERR------------------------------------------------LMKGFNIAPPGSTGSLAPVAEFSTSLDNYDNQHEIL--------------SSTLSTLFTPNFMHKRQQSQAGSGGGGSESPTTPTAPQGTQGAAMTASSQVTKYNKSALKPYNKRIAGHKKRWGTLIEAAKVGNVSKMLGRSKSEDSVCNSSHTSTPVHGQMRVTYAQNSPQQEYGYHGETSSTTISTPTPTISVVSNSPAAHAGVGSHFFHTTSGLTAIAALKRKRKKFSSSKNICPVTESVAAANAAEILNDKTLKRVSSYP-----------AAEAGVQHNPAQLVKPRRHEQTQSQHDSVETNSTFTLSIDPSNTSVNSREPLISTSCVSTTGAIG--------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P19334-1", "uniprot_id": "TRP_DROME", "id": "P19334-1", "name": "Transient receptor potential protein", "aln": "MG---------SNTESDAEKALGSRLDYDLMMAEEYILSDVEKNFILSCERGDLPGVKKILEEYQGTDKFNINCTDPMNRSALISAIENENFDLMVILLEHNIEVGDALLHAISEEYVEAVEELLQWEETNHKEGQPYSWEAVDRSKSTFTVDITPLILAAHRNNYEILKILLDRGATLPMPHDVKCGCDECVTSQMTDSLRHSQSRINAYRALSASSLIALSSRDPVLTAFQLSWELKRLQAMESEFRAEYTEMRQMVQDFGTSLLDHARTSMELEVMLNFNHEPSHDIWCLGQRQTLERLKLAIRYKQKTFVAHPNVQQLLAAIWYDGLPGFRRKQASQQLMDVVKLGCSFPIYSLKYILAPDSEGAKFMRKPFVKFITHSCSYMFFLMLLGAASLRVVQITFELLAFP-WMLTMLEDWRKHERGSLPGPIELAIITYIMALIFEELKSLYSDGLFEYIMDLWNIVDYISNMFYVTWILCRATAWVIVHRDLWFRGIDPYFPREHWHPFDPMLLSEGAFAAGMVFSYLKLVHIFSINPHLGPLQVSLGRMIIDIIKFFFIYTLVLFAFGCGLNQLLWYYAELEKNKCYHLHPDV----ADFDDQEKACTIWRRFSNLFETSQSLFWASFGLVDLVSFDLAGIKSFTRFWALLMFGSYSVINIIVLLNMLIAMMSNSYQIISERADTEWKFARSQLWMSYFEDGGTIPPPFNLCPN-------MKMLRKTLGR----KRPSRTKSFMRKSMER--AQTLHDKVMKLLVRRYITAEQRRRD-DYGITEDDIIEVRQDISSLRFELLEIFTNNNWDVPDIEKKSQGVARTTKGKVMERRILKDFQIGFVENLKQEMSESESGRDIFSSLAKVIGRKKTQKGDKDWNAIARKNTFASDPIGSKRSSMQRHSQRSLRRKIIEQANEGLQMNQTQLIEFNPNLGDVTRATRVAYVKFMRKKMAADEVSLADDEGAPNGEGEKKPLDASGSKKSITSGGTGGGASMLAAAALRASVKNVDEKSGADGKPGTMGKPTDDKKAGDDKDKQQPPKDSKPSAGGPKPGD--QKPTPGAGAPKPQAAGTISKPGESQKKDAPAPPTKPGDTKPAAPKPGESAKPEAAAKKEESSKTEASKPAATNGAAKSAAPSAPSDAKPDSKLKPGAAGAPEATKATNGASKPDEKKSGPEEPKKAAGDSKPGDDAKDKDKKPGDDKDKKPGDDKDKKPADNNDKKPADDKDKKPGDDKDKKPGDDKDKKPSDDKDKKPADDKDKKPAAAPLKPAIKVGQSSAAAGGERGKSTVTGRMISGWL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P48994-1", "uniprot_id": "TRPL_DROME", "id": "P48994-1", "name": "Transient-receptor-potential-like protein", "aln": "MGRKKKLPTGVSSGVSHASSAPKSVGGCCVPLGLPQPLLLEEKKFLLAVERGDMPNVRRILQKALRHQHININCMDPLGRRALTLAIDNENLEMVELLVVMGVETKDALLHAINAEFVEAVELLLEHEELIYKEGEPYSWQKVDINTAMFAPDITPLMLAAHKNNFEILRILLDRGAAVPVPHDIRCGCEECVRLTAEDSLRHSLSRVNIYRALCSPSLICLTSNDPIITAFQLSWELRNLALTEQECKSEYMDLRRQCQKFAVDLLDQTRTSNELAIILNY--DPQMSSYEPGDRMSLTRLVQAISYKQKKFVAHSNIQQLLSSIWYDGLPGFRRKSIVDKVICIAQVAVLFPLYCLIYMCAPNCRTGQLMRKPFMKFLIHASSYLFFLFILILVSQRADDDFVRIFGTT-RMKKELAEQELRQRGQTPSKLELIVVMYVIGFVWEEVQEIFAVGMKSYLRNMWNFIDFLRNSLYVSVMCLRAFAYIQQATEIARDPQMAYIPREKWHDFDPQLIAEGLFAAANVFSALKLVHLFSINPHLGPLQISLGRMVIDIVKFFFIYTLVLFAFACGLNQLLWYFAALEKSKCYVLPGGE----ADWGSHGDSCMKWRRFGNLFESSQSLFWASFGMVGLDDFELSGIKSYTRFWGLLMFGSYSVINVIVLLNLLIAMMSNSYAMIDEHSDTEWKFARTKLWMSYFEDSATLPPPFNVLPS-------VKWVIRIFRKSS--KTIDRQRSKKRKEQE---QFSEYDNIMRSLVWRYVAAMHRKFE-NNPVSEDDINEVKSEINTMRYEMLEIFENSGMDVSSANKKER-QPRPRRIKVWERRLMKGFQVAPVQN--------GCELDAFG----------NVNGQGEMQEIKVESIPSKPAKETAKERFQRVARTVLLQSTTHKWNVVLRAAK------DSQIGRCTKNERKSLQNLGRAIEEAKRLIMLN-PGCPSGRESPIRIEFEDEK----------------TSTLLELLNQISAEISDSEKP-------------KIRPIWRPPLKTVP----ARAMA--ANNTRSLTAPELKIS--------RKSSPAPTPTPTPGVSHTALSQFRNRELPLCPSKLIAN-----SAPSAPTAPPKKSAPTAPTPT-----YKP-TTHAPFSVEGGN------------RENTRASDGVRSDNSNFDIHVVDLDEKGGHLGRDNVSDISSIASTSPQRPKHRN---------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ** :: : *:** ...: *:: :*:** **:.* ** **:***:::: :*: .: . *****:* * * *** **: : . . . : *: ****::**** :*:**:::*:::*. :* **:::*.* *** ****** **:* *:**.:.***.*:*.**.:***:*****:.* * * : ** :: : :.*. ***::*:* ** ::**. * ** ** :** ***:.* ****:: **: :**:**: : : :. **: .: *: ** . . :****:**: *:.**: **::* .* : .:* * :* :: :: .::: *::.:: *: .*: : **.:*:: * :*:: : : ::. **: *. :.* *::*. *: . :** *:*: :*: *.******:**.**::**:**:*:* ***:**. ***** :*: : * : : .. *..***: *:***: **::.* :: . : :* * . ***:*.**.::****:*****.:** * :::* ******::**:****:..* *.***: *. :. : . . : *: : :::::: ** **::. * . . ::*::. *::.:*.::* *:: :: .. .. . . : . : .. : . . .. .. : ", "identical_positions": 250, "similar_positions": 254, "identity": "19.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120329-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AP41-1", "uniprot_id": "A0A8I6AP41_RAT", "id": "A0A8I6AP41-1", "name": "Neurobeachin", "aln": "MASDKPGPG--LEPQPVALLAVGAGGSGSGGG--------AMGEPRGAAGSGSGSVVLPAGMINPSVPIRNIRMKFAVLIGLIQVGEVSNRDIVETVLNLLVGGEFDLEMNFIIQDAESITCMTELLEHCDVTCQAEIWSMFTAILRKSVRNLQTSTEVGLIEQVLLKMSAVDDMIADLLVDMLGVLASYSITVKELKLLFSMLRGESGIWPRHAVKLLSVLNQMPQRHGPDTFFNFPGCSAAAIALPPIAKWPYQNGFTLNTWFRMDPLNNINVDKDKPYLYCFRTSKGVGYSAHFVGNCLIVTSLKSKGKGFQHCVKYDFQPRKWYMISIVHIYNRWRNSEIRCYVNGQLVSYGDMAWHVNTNDSYDKCFLGSSETADANRVFCGQLGAVYVFSEALNPAQIFAVHQLGPGYKSTFKFKSESDIHLAEHHK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVLYDGKLASSIAFSYNAKATDAQLCLESSPKENASIFVHSPHALMLQDVKAIVTHSIHSAIHSIGGIQVLFPLFAQLDNR--QLNDSQVETTVCATLLAFLVELLKSSVAMQEQMLGGKGFLVIGYLLEKSSRVHITRAVLEQFLSFAKYLDGLSHG------------APLLKQLCDHILFNPAIWIHTPAKVQLSLYTYLSAEFIGTATIYTTIRRVGTVLQLMHTLKYYYWVINPADSSGITPKGLDGPRPSQKEIISLRAFMLLFLKQLILKDRGVKEDELQSILNYLLTMHEDENIHDVLQLLVALMSEHPASMIPAFDQRNGIRVIYKLLASKSESIWVQALKVLGYFLKHLGHKRKVEIMHTHSLFTLLGERLMLHTNTVTVTTYNTLYEILTEQVCTQVVHKPHPEPDSTVKIQNPMILKVVATLLKNSTPSAELMEVRRLFLSDMIKLFSNSRENRRCLLQCSVWQDWMFSLGYINPKSSEEQKITEMVYNIFRILLYHAIKYEWGGWRVWVDTLSIAHSKVTYEAHKEYLAKMYEEYQRQEEENIKK---GKKGNVSTISGLS------------------SQTAGAKGGMEIREIEDLSQSQSPESE---------TDYPVSTDT----------------------------------------------------------------------------RDLLMSTKVSDDILGGSDRPGSGVHVEVHDLLVD----IKAEKVEATE--------------VKLDDMDLSPETLVGGENGALVEVESLLDN--------------VYSAAVEKLQNNVHGSVGIIKKNEEKDNGPLITLADEKEELPNSSTSFLF------------DKLPK-QEEKLLPELSSNHIIPN-IQDTQVHLGVTDDLG-----------------------LLAHMT-ASVELTCTSSIMEEKDFRIHTTSDGVSSVSERELASSTKGLDYAEMTATTLETESSNSKTVPNIDAGSIISDTERSDD---------------------------------------------------------------------------------------GKESGKEIRKIQTTATTQAVQGRS-------------------------------------STQQDRDLRVDLGFRGMPMTEEQ--------------------------------------------RRQFSPGPRTTMFRIPEFKWSPMHQRLLTDLLFALETDVHVWRSHSTKSVMDFVNSNENIIFVHNTIHLISQMVDNIIIACGGILPLLSAATSPT---TELENIEVTQGMSAETAVTFLSRLMAMVDVLVFASSLNFSEIEAEKNMSSGGLMRQCLRLVCCVAVRNCLECRQRQR-DRGNKSSHGSSKPQEAPQSVTATAASKTPLENVPGNLSPIKDPDRLLQDVDINRLRAVVFRDVDDSKQAQFLALAVVYFISVLMVSKYRDILEP------QRETARTGSQPGRNIRQEINSPTSTVVVIPSIPHPSLNHGLLAKLMPEQSFAHSFYKETPATFPDTIKEKETPTPGEDIQLESSVPHTDSGMGEEQVASILDGAELETAAG-PDAMSELLSTLSSEVKKSQESLTE-HPSEMLKPAPSISSISQT-KGINVKEILKSLVAAPVEIAECGPEPIPYPDP-ALKREAHAILPMQFHSFDRSVVVPVKKPPPGSLAVTTVGATAAGSGLPTGSTSSIFAAPGATPKSMINTTGAVDSGSSSSSSS---SSFVNGATSKNLP--------AVQTVAPMPEDS-AENMSITAKLERALEKVAPLLREIFVDFAPFLSRTLLGSHGQELLIEG--LVCMKSSTSVVELVMLLCSQEWQNSIQKNAGLAFIELINEGRLLCHAMKDHIVRVANEAEFILNRQRAEDVHKHAEFESQCAQYAADRREEEKMCDHLISAAKHRDHVTANQLKQKILNILTNKHGAWGAVS-----------HSQLHDFWRLDYWEDDLRRRRRFVRNAFGSTHAEALLKSAVEYGTEED-VVKSKKAFRSQAIVNQNSET-ELMLEGDDDAVSLLQEKEIDN-LAG-----------PVVLSTPAQLIAPVVVAKGTLSITTTEIYFEVDEDDAAFKKIDTKVLAYTEGLHGKWMFSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYSLPRVGVGTSYGLPQARRISLATPRQLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLPGNFRDLSKPIGALNPKRAVFYAERYETWEDDQSPPYHYNTHYSTATSALSWLVRIEPFTTFFLNANDGKFDHPDRTFSSIARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYHLGVREDEVLVNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSIS-DPVLREIPEAYFIRDPHTFLLTKDSIKAMEAQIQNFGQTPSQLLIEPHPPRSSAMHLCFLPQSPLMFKDQMQQDVIMVLKFPSNSPVTHVAANTLPHLTIPAVVTVTCSRLFAVNRWHN-TVGLRGAPGYS---LDQAHHLPIEMDPLIANN------SGVNKRQITDLVDQSIQINAHCFVVTADNRYILICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLWYWSGRHHIIGDNPNSSDYPAPRAVLTGHDHEVVCVSVCAELGLVISGAKEGPCLVHTITGDLLRALEGPENCLFPRLISVSSEGHCIIYYERGRFSNFSINGKLLAQMEINDSTRAILLSSDGQNLVTGGDNGVVEVWQACDFKQLYIYPGCDAGIRAMDLSHDQRTLITGMASGSIVAFNIDFNRWHYEHQNRY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9EPN1-1", "uniprot_id": "NBEA_MOUSE", "id": "Q9EPN1-1", "name": "Neurobeachin", "aln": "MASDKPGPG--LEPQPVALLAVGAGGGAGGGG--------AMGEPRGAAGSGP--VVLPAGMINPSVPIRNIRMKFAVLIGLIQVGEVSNRDIVETVLNLLVGGEFDLEMNFIIQDAESITCMTELLEHCDVTCQAEIWSMFTAILRKSVRNLQTSTEVGLIEQVLLKMSAVDDMIADLLVDMLGVLASYSITVKELKLLFSMLRGESGIWPRHAVKLLSVLNQMPQRHGPDTFFNFPGCSAAAIALPPIAKWPYQNGFTLNTWFRMDPLNNINVDKDKPYLYCFRTSKGVGYSAHFVGNCLIVTSLKSKGKGFQHCVKYDFQPRKWYMISIVHIYNRWRNSEIRCYVNGQLVSYGDMAWHVNTNDSYDKCFLGSSETADANRVFCGQLGAVYVFSEALNPAQIFAVHQLGPGYKSTFKFKSESDIHLAEHHK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVLYDGKLASSIAFSYNAKATDAQLCLESSPKENASIFVHSPHALMLQDVKAIVTHSIHSAIHSIGGIQVLFPLFAQLDNR--QLNDSQVETTVCATLLAFLVELLKSSVAMQEQMLGGKGFLVIGYLLEKSSRVHITRAVLEQFLSFAKYLDGLSHG------------APLLKQLCDHILFNPAIWIHTPAKVQLSLYTYLSAEFIGTATIYTTIRRVGTVLQLMHTLKYYYWVINPADSSGIAPKGLDGPRPSQKEIISLRAFMLLFLKQLILKDRGVKEDELQSILNYLLTMHEDENIHDVLQLLVALMSEHPASMIPAFDQRNGIRVIYKLLASKSESIWVQALKVLGYFLKHLGHKRKVEIMHTHSLFTLLGERLMLHTNTVTVTTYNTLYEILTEQVCTQVVHKPHPEPDSTVKIQNPMILKVVATLLKNSTPSAELMEVRRLFLSDMIKLFSNSRENRRCLLQCSVWQDWMFSLGYINPKSSEEQKITEMVYNIFRILLYHAIKYEWGGWRVWVDTLSIAHSKVTYEAHKEYLAKMYEEYQRQEEENIKK---GKKGNVSTISGLS------------------SQTAGAKGGMEIREIEDLSQSQSPESE---------TDYPVSTDT----------------------------------------------------------------------------RDLLMSTKVSDDILGSSDRPGSGVHVEVHDLLVD----IKAEKVEATE--------------VKLDDMDLSPETLVGGENGALVEVESLLDN--------------VYSAAVEKLQNNVHGSVGIIKKNEEKDNGPLITLADEKEELPNSSTPFLF------------DKIPR-QEEKLLPELSSNHIIPN-IQDTQVHLGVSDDLG-----------------------LLAHMT-ASVELTCTSSIMEEKDFRIHTTSDGVSSVSERELASSTKGLDYAEMTATTLETESSNSKAVPNVDAGSIISDTERSDD---------------------------------------------------------------------------------------GKESGKEIRKIQTTATTQAVQGRS-------------------------------------STQQDRDLRVDLGFRGMPMTEEQ--------------------------------------------RRQFSPGPRTTMFRIPEFKWSPMHQRLLTDLLFALETDVHVWRSHSTKSVMDFVNSNENIIFVHNTIHLISQMVDNIIIACGGILPLLSAATSPTGSKTELENIEVTQGMSAETAVTFLSRLMAMVDVLVFASSLNFSEIEAEKNMSSGGLMRQCLRLVCCVAVRNCLECRQRQR-DRGSKSSHGSSKPQEAPHSVTAASASKTPLENVPGNLSPIKDPDRLLQDVDINRLRAVVFRDVDDSKQAQFLALAVVYFISVLMVSKYRDILEP------QRETARTGSQPGRNIRQEINSPTSTVVVIPSIPHPSLNHGLLAKLMPEQSFAHSFYKETPATFPDTVKEKETPTPGEDIQLESSVPHTDSGMGEEQVASILDGAELEPAAG-PDAMSELLSTLSSEVKKSQESLTE-HPSEMLKPAPSISSISQT-KGINVKEILKSLVAAPVEIAECGPEPIPYPDP-ALKREAHAILPMQFHSFDRSVVVPVKKPPPGSLAVTTVGATAAGSGLPTGSTSSIFAAPGATPKSMINTTGAVDSGSSSSSSS---SSFVNGATSKNLP--------AVQTVAPMPEDS-AENMSITAKLERALEKVAPLLREIFVDFAPFLSRTLLGSHGQELLIEG--LVCMKSSTSVVELVMLLCSQEWQNSIQKNAGLAFIELINEGRLLCHAMKDHIVRVANEAEFILNRQRAEDVHKHAEFESQCAQYAADRREEEKMCDHLISAAKHRDHVTANQLKQKILNILTNKHGAWGAVS-----------HSQLHDFWRLDYWEDDLRRRRRFVRNAFGSTHAEALLKSAVEYGTEED-VVKSKKAFRSQAIVNQNSET-ELMLEGDDDAVSLLQEKEIDN-LAG-----------PVVLSTPAQLIAPVVVAKGTLSITTTEIYFEVDEDDAAFKKIDTKVLAYTEGLHGKWMFSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYSLPRVGVGTSYGLPQARRISLATPRQLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLPGNFRDLSKPIGALNPKRAVFYAERYETWEEDQSPPFHYNTHYSTATSALSWLVRIEPFTTFFLNANDGKFDHPDRTFSSIARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYHLGVREDEVVVNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSIT-DPVLREA---------------------MEAQIQNFGQTPSQLLIEPHPPRSSAMHLCFLPQSPLMFKDQMQQDVIMVLKFPSNSPVTHVAANTLPHLTIPAVVTVTCSRLFAVNRWHN-TVGLRGAPGYS---LDQAHHLPIEMDPLIANN------SGVNKRQITDLVDQSIQINAHCFVVTADNRYILICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLWYWSGRHHIIGDNPNSSDYPAPRAVLTGHDHEVVCVSVCAELGLVISGAKEGPCLVHTITGDLLRALEGPENCLFPRLISVSSEGHCIIYYERGRFSNFSINGKLLAQMEINDSTRAILLSSDGQNLVTGGDNGVVEVWQACDFKQLYIYPGCDAGIRAMDLSHDQRTLITGMASGSIVAFNIDFNRWHYEHQNRY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFP9-1", "uniprot_id": "NBEA_HUMAN", "id": "Q8NFP9-1", "name": "Neurobeachin", "aln": "MASEKPGPGPGLEPQPVGLIAVGAAGGGGGGSGGGGTGGSGMGELRGASGSGS--VMLPAGMINPSVPIRNIRMKFAVLIGLIQVGEVSNRDIVETVLNLLVGGEFDLEMNFIIQDAESITCMTELLEHCDVTCQAEIWSMFTAILRKSVRNLQTSTEVGLIEQVLLKMSAVDDMIADLLVDMLGVLASYSITVKELKLLFSMLRGESGIWPRHAVKLLSVLNQMPQRHGPDTFFNFPGCSAAAIALPPIAKWPYQNGFTLNTWFRMDPLNNINVDKDKPYLYCFRTSKGVGYSAHFVGNCLIVTSLKSKGKGFQHCVKYDFQPRKWYMISIVHIYNRWRNSEIRCYVNGQLVSYGDMAWHVNTNDSYDKCFLGSSETADANRVFCGQLGAVYVFSEALNPAQIFAIHQLGPGYKSTFKFKSESDIHLAEHHK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVLYDGKLASSIAFTYNAKATDAQLCLESSPKENASIFVHSPHALMLQDVKAIVTHSIHSAIHSIGGIQVLFPLFAQLDNR--QLNDSQVETTVCATLLAFLVELLKSSVAMQEQMLGGKGFLVIGYLLEKSSRVHITRAVLEQFLSFAKYLDGLSHG------------APLLKQLCDHILFNPAIWIHTPAKVQLSLYTYLSAEFIGTATIYTTIRRVGTVLQLMHTLKYYYWVINPADSSGITPKGLDGPRPSQKEIISLRAFMLLFLKQLILKDRGVKEDELQSILNYLLTMHEDENIHDVLQLLVALMSEHPASMIPAFDQRNGIRVIYKLLASKSESIWVQALKVLGYFLKHLGHKRKVEIMHTHSLFTLLGERLMLHTNTVTVTTYNTLYEILTEQVCTQVVHKPHPEPDSTVKIQNPMILKVVATLLKNSTPSAELMEVRRLFLSDMIKLFSNSRENRRCLLQCSVWQDWMFSLGYINPKNSEEQKITEMVYNIFRILLYHAIKYEWGGWRVWVDTLSIAHSKVTYEAHKEYLAKMYEEYQRQEEENIKK---GKKGNVSTISGLS------------------SQTTGAKGGMEIREIEDLSQSQSPESE---------TDYPVSTDT----------------------------------------------------------------------------RDLLMSTKVSDDILGNSDRPGSGVHVEVHDLLVD----IKAEKVEATE--------------VKLDDMDLSPETLVGGENGALVEVESLLDN--------------VYSAAVEKLQNNVHGSVGIIKKNEEKDNGPLITLADEKEDLPNSSTSFLF------------DKIPK-QEEKLLPELSSNHIIPN-IQDTQVHLGVSDDLG-----------------------LLAHMT-GSVDLTCTSSIIEEKEFKIHTTSDGMSSISERDLASSTKGLEYAEMTATTLETESSSSKIVPNIDAGSIISDTERSDD---------------------------------------------------------------------------------------GKESGKEIRKIQTTTTTQAVQGRS-------------------------------------ITQQDRDLRVDLGFRGMPMTEEQ--------------------------------------------RRQFSPGPRTTMFRIPEFKWSPMHQRLLTDLLFALETDVHVWRSHSTKSVMDFVNSNENIIFVHNTIHLISQMVDNIIIACGGILPLLSAATSPTGSKTELENIEVTQGMSAETAVTFLSRLMAMVDVLVFASSLNFSEIEAEKNMSSGGLMRQCLRLVCCVAVRNCLECRQRQR-DRGNKSSHGSSKPQEVPQSVTATAASKTPLENVPGNLSPIKDPDRLLQDVDINRLRAVVFRDVDDSKQAQFLALAVVYFISVLMVSKYRDILEP------QRETTRTGSQPGRNIRQEINSPTSTVVVIPSIPHPSLNHGFLAKLIPEQSFGHSFYKETPAAFPDTIKEKETPTPGEDIQVESSIPHTDSGIGEEQVASILNGAELETSTG-PDAMSELLSTLSSEVKKSQESLTE-NPSETLKPATSISSISQT-KGINVKEILKSLVAAPVEIAECGPEPIPYPDP-ALKRETQAILPMQFHSFDRSVVVPVKKPPPGSLAVTTVGATTAGSGLPTGSTSNIFAATGATPKSMINTTGAVDSGSSSSSSS---SSFVNGATSKNLP--------AVQTVAPMPEDS-AENMSITAKLERALEKVAPLLREIFVDFAPFLSRTLLGSHGQELLIEG--LVCMKSSTSVVELVMLLCSQEWQNSIQKNAGLAFIELINEGRLLCHAMKDHIVRVANEAEFILNRQRAEDVHKHAEFESQCAQYAADRREEEKMCDHLISAAKHRDHVTANQLKQKILNILTNKHGAWGAVS-----------HSQLHDFWRLDYWEDDLRRRRRFVRNAFGSTHAEALLKAAIEYGTEED-VVKSKKTFRSQAIVNQNAET-ELMLEGDDDAVSLLQEKEIDN-LAG-----------PVVLSTPAQLIAPVVVAKGTLSITTTEIYFEVDEDDSAFKKIDTKVLAYTEGLHGKWMFSEIRAVFSRRYLLQNTALEVFMANRTSVMFNFPDQATVKKVVYSLPRVGVGTSYGLPQARRISLATPRQLYKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNYESEELDLTLPGNFRDLSKPIGALNPKRAVFYAERYETWEDDQSPPYHYNTHYSTATSTLSWLVRIEPFTTFFLNANDGKFDHPDRTFSSVARSWRTSQRDTSDVKELIPEFYYLPEMFVNSNGYNLGVREDEVVVNDVDLPPWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAVRALNVFHYLTYEGSVNLDSIT-DPVLREA---------------------MEAQIQNFGQTPSQLLIEPHPPRSSAMHLCFLPQSPLMFKDQMQQDVIMVLKFPSNSPVTHVAANTLPHLTIPAVVTVTCSRLFAVNRWHN-TVGLRGAPGYS---LDQAHHLPIEMDPLIANN------SGVNKRQITDLVDQSIQINAHCFVVTADNRYILICGFWDKSFRVYSTETGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLWYWSGRHHIIGDNPNSSDYPAPRAVLTGHDHEVVCVSVCAELGLVISGAKEGPCLVHTITGDLLRALEGPENCLFPRLISVSSEGHCIIYYERGRFSNFSINGKLLAQMEINDSTRAILLSSDGQNLVTGGDNGVVEVWQACDFKQLYIYPGCDAGIRAMDLSHDQRTLITGMASGSIVAFNIDFNRWHYEHQNRY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HD37-1", "uniprot_id": "A0AC58HD37_DANRE", "id": "A0AC58HD37-1", "name": "Neurobeachin", "aln": "MASVLPVATPGDRAPPPGYRQHGAAVTAATSS--------GTSDIMMMSCSGS--VVLPAGMINPSVPIRNIKTKFAVLIGLIQVGEVSNRDIVETVLNLLVGGEFDLEMNFIIQDAEAIICMLELLEHCEVTCQAEIWSMFTAILRKSVRNLQTSSEVGLIQRLLIKMSSVDDMIADLLVDMLGVLASYSITVKELKLLFSMLRGEGGLWPRHAVKLLSVLSQMAQRHGPDTFFNFPGRSAAAIALPPIAKWPYQNGFTLNTWFRMDPLNNINVDKDKPYLYCFRTSKGIGYSAHFVGNCLIVTSLKSKGKGFQHCVKYDFQPRKWYMVSIVHIYNRWRNSEIRCYVNGQLVSYGDMAWHVNTNDSYDKCFLGSSETADANRVFCGQLGAIYVFSEALNPAQIFAIHQLGPGYKSTFKFKSESDIHLADHHK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVLYDGKLANSISFTYNAKATDAQLCLESSPRENPSIFVHSPHALMLQDVKAIVTHSIHSAIHSIGGIQVLFPLFAQLDFH--QHNESQVETTVCSTLLAFLMELLKSSVAMQEQMLGGKGFLVIGYLLEKSSRVHVTRAVLDQFLSFAKYLDGLTHG------------APLLKQLCDHILFNAAIWIHIPAKVQLSLYTYLSSEFIGTTTIYSTIRRVGTVLQIMHILKYYYWAVNPNNTSGITPKGLDGPRPSQKEISSLRAFMLLFLKQLILKDRGVKEDELQSILNYLLTMHEDENLHDVLQLLVALMSEHPASMIPAFDQRNGIRVVYKLLASKSESIRVQALKVLAYFLKHLGHKRKVEIMHTNSLFTLLGERLMLHSNTVSITTYNTLYEILTEQVCTQVVHKPHVEPDSTVKIQNPMILKVVATLLKNSTPSADLMEVRRLFLSDMIKLFSNSRENRRCLLQCSVWQDWMFSLGYINPKNSEEQKITEMVYNIFRILLYHAIKHEWGGWRVWVDTLSIAHSKVTYEAHKEYLAKMYEEYQRQEEENIKK---GKKGLVSTISGLS------------------AQASSIKG---TLELDADSQTQTPESE---------ADEPETTDSG---------------------------------------------------------------------------RNILSETKSLD-----EDNPASGVHVEVHDLLVD----IKAEKVEATE--------------VKMDDLDLLPVT----ENGGLVEVDSLLDN--------------VYSAAVEKLNSSVNNVLVPKASLENKNSGPLITLADEKDAIS-SNNTFLF------------GTLASGSGENLLPEIGPSEPLPLSGVEPQVHTSSSADLG-----------------------LLALMSKSSKELSANTVALEDDSFKMQPALSGFS-ISEG--ESLTKCPGQVETVAVDLEQGASGVKDVS-------TSDTEKSDD---------------------------------------------------------------------------------------GKE--KEIKKIQTTATTQSLHGRS-------------------------------------GSHLDRDLRVDLGFRAMPMTEEQ--------------------------------------------RRQFSPGPRTTMFRIPEFKWSPMHQRLLTDLLFALESDVHIWRSHSTKSIMDFVNSNENIIFVHNTIHLISQMVDNIIIACGGILPLLSAATSPS---SEMEGLEVTQGMSSETAVIFLTRLMAIVDVLVFASSLNFSEIEAEKNMSSGGLMRQCLRLVCCVAVRNCLECRQRQR-DRSLKSSLSCSKSQEGLQSVS--TASKTTIENFPSNVSPIKDPDRLLQDVDINRLRAAVFRDVDDSKQAQFLALAVVYFISVLMVSKYRDILEP------QRETGRFINQSGRGIRQEINSPTS--------------------------------TDHPSLLTDSRKEALGVLES---RQESSLPHSDSGLGDDQVSSVMNGADLDLAMGGPNGMSGLFCTLSSVAR-SQESLIEPSSVEHLKTASSISSINQANKGINVKEILKSLVAAPVETTESGTEALPYPEQQAMKREAQAMMPMQFHSFDRSVVVQAKKPPSG-LTVNTVGTSGSSSALTSGSTPNIFAAASITPKSMINTTGATDT---SSSSS---ASFVNGATSKNLP--------AVQTVAPMPEDT-MENMSITTKLERALEKVAPLLREIFVDFAPFLSRTLLGSHGQELLIEG--LVCMKSSTSVVELVMLLCSQEWQNSIQKNAGLAFIELINEGRLLCHAMKDHIVRVANEAEFILNRQRAEDVHKHAEFESSCAQYAADRKEEETMCDHLISAAKHRDHVTANQLKQKILNILTNKHGAWGAAAQRSSCLFPFSSQQQQHDFWRLDYWEDDLRRRRRFIRNPFGSTHLDITCKSLEDYGPEEDEALRGRKGFRGQASVSQNTET-ELMLEGDDDAVSLLQEKEVDN-LAASLYPRVNVSRGPVVLSTPAQLIAPVTVARGTLSITTTEIYFEVDEDDPAFRRIDAKVLVYSEGLHGKWMFSEIRAVFTRRFLLQNTALEIFMANRTSVMFNFPDQPTVKKVVYSLPCVGVGTSYGLPQARRISLASPRQLFKSSNMTQRWQRREISNFEYLMFLNTIAGRTYNDLNQYPVFPWVLTNFESEELDLTVPSNFRDLSKPIGALNPKRAVFYADRYESWD-EETPPCHYTTHYSTANSTLHWLVRIEPFTTFFLNANGNKFDHPNRTFSSIARSWRHCQRDTADVKELIPEFYYLPEMFVNSNGYCLGDRDDGVPVCDVELPAWAKKPEDFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAARALNVFHHLTYEGSVNLDSLASDPPLREA---------------------TEAQIQSVGQSPSQLLIEPHPPRSSAMHLCFLPQSPLMFKDQMQQDVIMVLKFPSNSPVTHVAANTLPHLTLPAVVTVTCSRLFAVNRWHN-TVGLRGAPGYS---LEQAHHLPIEMDSLIANN------SGTNKRQITDLVDQSIQINTQCFVVTADNRYILVCGFWDKSFRVYSSDTGKLTQIVFGHWDVVTCLARSESYIGGDCYIVSGSRDATLLLWYWSGRHHIIGDNPNNSDYPAPRAVLTGHDFEVVCVSVCAELGIIISGAKEGPCLVHTITGDLLRALEGPDSCVLPRLICVSSEGHCIIYFDRGQFCSFSINGKLLAQMEINDSTRAIVLSSDGQNLVTGGDNGVVEVWQACDFKQLYVYPGCDAGVRAMDLSHDQRTLVTGMASGSIVAFNIDFNRWHFEHQNRY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W4E2-5", "uniprot_id": "NBEA_DROME", "id": "Q9W4E2-5", "name": "Neurobeachin", "aln": "MADIMRPPYSEIKRP---------------------------DEIVRMTTADN--------------------LKFAVLIGLIEVGQVTNREVVNTVLHLLVGGEFDMELNFVIQDAQNIKHMLELLDHCPPNLQAEIWSVFIAILRKSVRNLQACTDVGLIEHVLVRLQRSETVVADLLIEMLGVLASYSITVKELKLLFGTMKATNGKWPRHSAKLLNVLRQMPHRNGPDVFFSFPGRKGSAMVLPPLAKWPYENGFTFTTWFRLDPINSVNIEREKPYLYCFKTSKGVGYTAHFVGNCLVLTSMKVKGKGFQHCVKYEFQPRKWYMIAIVYIYNRWTKSEIKCLVNGQLASSTEMAWFVSTNDPFDKCYIGATPELDEERVFCGQMSAIYLFSEALTTQQICAMHRLGPGYKSQFRFDNECYLNLPDNHKRVSHFQLLPATLGASALSGGSGSGTGSGTGNDASAAAAAAVAAGQQQQLQLQFQILAAEQEARAIDWSDEKLDLNAAFVKIRAVLTARNAVTLAGSSSTGTTAVATAAAAAAAAGAGAGTTAAATSAAAAAAATQNENDAAVGQQQHATHHHATAATGSADDPLGHLPTGNASSSSSSFEQLRRMSSVSSLNSMVGSADTEEVNQLKAVLYDGKLSNAIVFMYNPVATDGQLCLQSSPKGNVSYFVHTPHALMLQDVKAVVTHSIHCTLNSIGGIQVLFPLFSQLDMAHEGLGDIKRDPTLCSKLLGFICELVETSQTVQQHMIQNRGFLVISFMLQRSSREHLTLEVLGSFLNLTKYLVTCLSANSDLLLKQLFCFSFLTWQLLDHVLFNPALWIYTPANVQARLYSYLATEFLSDTQIYSNVRRVSTVLQTVHTLKYYYWVVNPRAKSGIIPKGLDGPRPAQKDILAIRAYILLFLKQLIMIGNGVKEDELQSILNYLTTMHEDENLHDVLQMLISLMSEHPSSMVPAFDVKHGVRSIFKLLAAESQLIRLQALKLLGFFLSRSTHKRKYDVMSPHNLYTLLAERLLLYEESLSLPTYNVLYEIMTEHISQQILYTRHPEPESHYRLENPMILKVVATLIRQSKQTESLIDVKKLFLQDMTLLCNSNRENRRTVLQMSVWQEWLIAMAYIHPKSSEEQKISDMVYSLFRMLLHHAIKHEYGGWRVWVDTLAIVHSKVSYEEFKLQFAQMYEHYERQRTDNITDPALRQARPISTISGWEREELHQQQNGGSAAAVATNQTAAVKGSVSIASLEDVPPVVEEEVEELELEEVEIQEGPITEETEQKSVIANISDVYNEQLKTDATCNGNLEDVKEEEPVQQQIGDLEKQPEPSTPLGALRETLQLGDDMDVEELELATAKDALNAEQHVSRVLQASEAALNDCKMAVDDVLQESSSVLKDEEIELAVNEVVQGVLNNEKKTQSQDNKDNKEQPGEQDVNVSLLNSKNLLNNNNNNNNNSPSPTPTTATATAETEAETEVNANEIVSSTEAPKAETETSVAPEVETPETAKPSPIVPSPVLATNQKTEDAANKLNNNEKLAEISASPEPPIVVETPEADLLQLSDSETKPNKETEAEDSVALAVRDIVEQLIDKVIDATEAESASETKTETNNNEIPKKEKQTSEEPEDVETAETLAAAAKEIVQEVVEAALVMVQEESTQEKPEKGANSEEEKNEIGKEEILLQLEEKPASTEVQETKIEGDLKKPEDPKGHSSVEPKTPNLEEPKPQETEQQKSQEVAEELPQKPEEQVVAIVNQVLDTLVDDTVKAVAAEQTTQTSPAPEEQSPQILAMESPATSVRVKPTEVDSTTQTTPKNEAGSSLLVEQVQQVLQEDDAQQSAGMTIEDEDYSNQQAAAAVENANSSQLDANHYGPGNPESKQQQQRSKSGSTRPMFSPGPTRPPFRIPEFKWSYIHQRLLSDVLFSLETDIQVWRSHSTKSVLDFVNSSENAIFVVNTVHLISQLADNLIIACGGLLPLLASATSPN---SELDVLEPTQGMPLEVAVSFLQRLVNMADVLIFATSLNFGELEAEKNMSSGGILRQCLRLVCTCAVRNCLECKERTRYNVGALARDVPGAAHLQALIRGAQASPKNIVESITGQLSPVKDPEKLLQDMDVNRLRAVIYRDVEETKQAQFLSLAIVYFISVLMVSKYRDILEPPAEPQIQRQSPVLQRTAGGGGRQIQDSDYEIIVVD---------------------------ENNPSVLADN-DSHSSGPPSIKANQTTTIATTTTTTATTHIN---NNNTKTTTSNAPTATIKIQQQPLSPPKPLVPQKLPKSVDSDVGSLNMNSTENEVPEVESSSEILIDDHKPSHSNDESWTDVNLNEDA-AVQAASAGIVVGLVD--NRGNVISDKHDPSHHNQQQQQQAGIIGQQQQHGSLG--HSERGDKPDSEISVVRVPDGYGGAGSGGGVNSGQGQGVPSNQRPRPEELPMKAPALVAQLPLTTPSREASLTQKLEIALGPVCPLLREIMVDFAPFLSKTLVGSHGQELLMEGKGLTTFKNSHSVVELVMLLCSQEWQNSLQKHAGLAFIELINEGRLLSHAMKDHIVRVANEAEFILNRMRADDVLKHADFESQCAQTLLERREEERMCDHLITAARRRDNVIASRLLEKVRNIMCNRHGAWGDSSSTSSGGAIVG-AVQKSPYWKLDAWEDDARRRKRMVQNPRGSSHPQATLKAALENGGPEDAILQTRDEFHTQIAVSRTHPSGQHNGELLDDAELLIEDRELDLDLTG-----------PVNISTKARLIAPGLVAPGTVSITSTEMFFEVDEEHPEFQKIDGEVLKYCDHLHGKWYFSEVRAIFSRRYLLQNVALEIFLASRTSILFAFPDQHTVKKVIKALPRVGVGIKYGIPQTRRASMMSPRQLMRNSNMTQKWQRREISNFEYLMFLNTIAGRTYNDLNQYPIFPWVLTNYESKDLDLSLPSNYRDLSKPIGALNPSRRAYFEERYESWDSDTIPPFHYGTHYSTAAFTLNWLVRVEPFTTMFLALQGGKFDYPDRLFSSVSLSWKNCQRDTSDVKELIPEWYFLPEMFYNSSGYRLGHREDGALVDDIELPPWAKSPEEFVRINRMALESEFVSCQLHQWIDLIFGYKQRGPEAIRATNVFYYLTYEGSVDLDGVL-DPVMREA---------------------VENQIRNFGQTPSQLLMEPHPPRSSAMHL-----SPMMFS-AMPEDLCQMLKFYQNSPVIHISANTYPQLSLPSVVTVTAGHQFAVNRWNCNYTASVQSPSYAESPQSPGSNQPLTIDPVLAVHGTNNNSNAASRRHLGDNFSQMLKIRSNCFVTTVDSRFLIACGFWDNSFRVFATETAKIVQIVFGHFGVVTCMARSECNITSDCYIASGSADCTVLLWHWNARTQSIVGE---GDVPTPRATLTGHEQAVTSVVISAELGLVVSGSSNGPVLIHTTFGDLLRSLDPPAEFHSPELITMSREGFIVINYDKGNVAAYTINGKKLRHETHNDNLQCMLLSRDGEYLMTAGDRGIVEVWRTFNLAPLYAFPACNAGIRSLALTHDQKYLLAGLSTGSIIVFHIDFNRWHHEYQQRY", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. . . .: : :. *********:**:*:**::*:***:********:*:**:****: * * ***:** . ******:* ***********:.::****:::*:::. : ::****::*******************. ::. .* ****:.***.** **.:*:***.**.*** ..:*:.***:*****:****:.****:**:*.:*::::*******:****:**:********::**:* ***********:********::**:***** :***:* *****.* :***.*.***.:***::*:: * :******:.*:*:*****.. ** *:*:******* *:*..*. ::*.::** *******:.:* * **. ***.****:***: * * ***:***********:******.:::************:*** .: : :.*:*:.**.*: **:::* ::*::*: .:*****.::*::*** *:* ** .**.::*** . : * ** **:***.*:**: **:** **:**::**:. : **:.:***.**** :* ******.:** .*** *********:**:* ::**::********: ..************** *******:*****:*::******:**:**** ::*:* ::****::*: * :****:*.:**.: **** ::* .:.*:***.***:*: :::::.***.****:**::. *:::. * **:* :::***********:::*. : .*::*::***.** * ...***** :** ****:*::::.**:**.******::***.:**:**:****:*:**********:*.****:** .* :*:***.*:**. :**.. : :***** . *::. ** .:: . * * : * : :: :: * : . .: . .. :: *.*:* : :* *::* : . *: * . * .*:: ..**:* . :*:.*. .. . . * . . ::* * : :. . :. . . :: *.*:... * .:.. * *: : .: :.. * .. .: . * .* : * * . :* : . :::*...: .: * : *** *: : . :* : :: *: * . :. ** *: * ***** . ********* :*****:*:**:**:*:::********::*****.** *** **:*****:.**:******:****::****. :*:: :* ****. *.** ** **: :.***:**:****.*:**********::******** ********::* * : . : . .: ::.*. :*....::**:***::****:*:*****.::***:::******:**:****************** **:: .* . ** :* . : *: :.*. .. . . :::. : : . :: :. : . * . : * : . . : . *: .:. : . .*** . .. . *. .: : *:: : .:: .. :*. *: *: *. : .. ** .: . .*.* *... . * :.*.. :. :*..*:: * * ** :* : .: *:* *** ** *.******:********:**:********:** *. :*.* *****************:**:***************.******************** **:** ***:***.*** :*:*** ******:**::**:* *.:* :*: **: *:***** : * :*:** **** ***:*:::*. **:* : *: : * ** :: :. *: * *.:. : : * *** *::::*:* *:. ** :** *:**** ** **:***:**::*****:.. *::** :** * : ***** ***:**:*:**:****.***:*:*.***::* **** *****: :** **** .**:**:** *: :**** :.*****:******************************:*******:**::***::*.*:************.* .:: :***:*: : ** ** ****** :* ****:*****:** :..***:*:* ***:: **: .****:********:*:***** **.** ** *:* . * *::**.***.**:*********************************** ** ***::*******:**.: ** :** * **:..**:*****:************ **:**. * :*: :*** .**** *::*** *:*::*:*****..: ******: .. :*.*: . . : *: :*.::* : ....:*:: * ..* ::*.::***.*.*.*::: *****:****::::*.*:.******:.****:****. * .****.*** *.*:***:*..* : * .: .* *:***.****: *..* :.****:::**:.:** *:** *****:*: * . *.** :* **. :* :::*... ::**** * : **. :.::** **: *:*.**.*:****:: :: ** :*.*:**:*:: *:***: *::*:::***:.*:*******.*:*:**", "identical_positions": 1417, "similar_positions": 818, "identity": "39.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120404-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P32238-1", "uniprot_id": "CCKAR_HUMAN", "id": "P32238-1", "name": "Cholecystokinin receptor type A", "aln": "MD--VVDSLLVNGSNITPP-CELGLENETLFCLD-QPRPS--KEWQPAVQILLYSLIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICKPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPNDVMQQSWHTFLLLILFLIPGIVMMVAYGLISLELYQGIKFEASQKKSAKERKPST-------TSSGKYEDSDGCYLQKTRPPRKLELRQLSTGSSS-RANRIRSNSSAANLMAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTASAERRLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCP--------NPGPPGARGEVGE--------EEEGGTTG-ASLSRFSYSHMSASVPPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O08786-1", "uniprot_id": "CCKAR_MOUSE", "id": "O08786-1", "name": "Cholecystokinin receptor type A", "aln": "MD--VVDSLLMNGSNITPP-CELGLENETLFCLD-QPQPS--KEWQSAVQILLYSFIFLLSVLGNTLVITVLIRNKRMRTVTNIFLLSLAVSDLMLCLFCMPFNLIPNLLKDFIFGSAVCKTTTYFMGTSVSVSTFNLVAISLERYGAICRPLQSRVWQTKSHALKVIAATWCLSFTIMTPYPIYSNLVPFTKNNNQTANMCRFLLPSDAMQQSWQTFLLLILFLIPGVVMVVAYGLISLELYQGIKFDASQKKSAKEKRLSSGGGGGGGSSSSRYEDSDGCYLQKSRPPRKLELQQLSTSSSGGRINRIRSSGSAANLIAKKRVIRMLIVIVVLFFLCWMPIFSANAWRAYDTVSAEKHLSGTPISFILLLSYTSSCVNPIIYCFMNKRFRLGFMATFPCCP--------NPGPTGVRGEVGE--------EEDGRTIR-ASLSRYSYSHMSTSAPPH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F402-1", "uniprot_id": "E7F402_DANRE", "id": "E7F402-1", "name": "Gastrin/cholecystokinin type B receptor", "aln": "METFTIQDMLVNSTDIYKILCGLGIGNLSECKNESTPSPSEPKDMNQTVRIVLYALIFILSFLGNSLIIAVLLRNRRMRTVTNLFLLSLAVSDLMLCVFCMPFTLIPNLMKDFIFGSGMCKVATYFMGISVSVSTLNLVAISLERYSAICNPLKSRAWQTKSHAVKVISATWVVSFLLMLPYPIGSTLVPFIRSNNSTGNMCRLVWPSDVMQT-WYIFLLLTLFLVPGIIMMTAYGLTSLELYRGIRFEMTNRKSNREKEYGT--------SSLKNGDSDGCYFQ---PSKKKRSEPVMPSHPKSKLRRVCSNSPTANLMAKKRVIRMLLVIVGLFFLCWTPVFVVNAWRAFDRRSADSLLSGAPISFIHLLSYTSACVNPIVYCFMNKRFRQGILSTFSCCRGDVDEFSRSSTRRSARGAGGLGTLFKGAGQTDGNTQTSGTLTKLTDTSVRGSAQA-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .::.:*:*.::* * **: * : : * ** *: : :*:*:**::**:**.***:*:*:**:**:*******:*************:*****.*****:*******.:**.:***** ******:**********.***.**:**.*******:***:*** :** :* **** *.**** :.**.*.****:: *.*.** * **** ***:**::*:.**** *****:**:*: :::** :*:. .: ** : ******:* *.:* . . : .. . : .*: *...:***:*********:*** ****** *:* .*****:* **: ***:***** ******:*****:********* *:::**.** .. ..** * : :* * .:*:: : : : *. . ", "identical_positions": 242, "similar_positions": 114, "identity": "52.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120406-10", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZ82-1", "uniprot_id": "D3ZZ82_RAT", "id": "D3ZZ82-1", "name": "Dynein regulatory complex subunit 7", "aln": "-------------MEVLREKVEEEEEAEREEAAERAERAEKAERVLKATEVSKEGIILSQDDLRDLEEKLM-AIEIPTPADHSVICQVPVDVTKLPPSYTTNSLKEEHLLLVADNFSRQYSHLCPDRVPLFLHPLNECNVPKFVSTTLRPTLMPYPELYN-WDSCAQFVSDFLTMVPLVDPLKPPTHLYSSTTVLQCQKGNCFDFSTLLCSMLIGSGYDAYCVNGYGSLDLCLMDLTREVCPLTVKAKEIVAKKEKV--APKKYAVKPPRDLTSRFEQEQEEKRLQAIKDQELKRLKEEEERLLEAEKAKPDPLHGLRVHSWVLVLSGK------------------REVPESFFIDPFTGRSYGTKDDHFLGIESLWNHKNYWINMQDCWNCCKDLIFDLGDPVRWEYMLLGTDKPHLSLTDDDDEGLDDDED--EDQGKEEEDKSFDMPPSWVAQIEITPEEFETRCPSGKKVIQYKKAQLEKWSPYLNNNGLVCRLTTYEDLQCTKVLEIKEWYQNREDMLELKHINKTTGLHVDYFKPGHPQALCVHSYKSMLPEMDRVMEFYKMIRVDGLVKREETPMTMTEYYQGRSDFLSYRHINFGPRVKKLTQNSADSNPRPVVKITEQFFRNPE-KPADEDVAERVFLIAEERIQLRYHCRDDYITANKREFLRRTEVDSKGNKIIMTPEMCISYEVEPMEHTKKLLYQYETMIHLKNEEKLSRHQAWESELEVLEILKLREEEEEAHTLTISIYDTKRNEKSKEYREAMERVLHEEHLRQVEAQLDYLAPFLAQLPPGEKLTRWQAVRLKDECLSDFKQRLIDKANLIQARFEKETQELQKKQQWYQENQVTLTPEDEDLYLSYCSQAMFRIRILEQRLNRHKELAPLKYLALEEKLYKDPRLIDFVKGFV--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6V3W6-1", "uniprot_id": "DRC7_MOUSE", "id": "Q6V3W6-1", "name": "Dynein regulatory complex subunit 7", "aln": "-------------MEVLREKVEEEEEAEREEAAERAERTEKLERVTKSAEVSREGTILSQDELRDLEGKLM-AIEIPTQADHSVISQAPVDVTKLPPSYTTNSLKEEHLLLVADNFSRQYSHLCPDRVPLFLHPLNECNVPKFVSTTLRPTLMPYPELYN-WDSCAQFVSDFLTMVPLVDPLKPPTHLYSSTTVLKCQKGNCFDFSTLLCSMLIGSGYDAYCVNGYGSLDLCLMDLTREVCPLTVKAKEIVKKKEKT--VPKKYSIKPPRDLTSKFEQEQEEKRIQEIKDLEQRRLKEEEDRILEAEKAKPDPLHGLRVHSWVLVLAGK------------------REVPESFFIDPLTARSYSTKDEHFLGIESLWNHKNYWINMQDCWNCCKDLIFDLGDPVRWEYMLLGTDKPHLSLTEEDEEGLDDDDDDVEDLGKEEEDKSFDMPSSWVSQIEITPEEFETRCPSGKKVIQYKKAQLEKWSPYLNNNGLVCRLTTYEDQQCTKVLEIKEWYQNREDMLELKHINKTTGLHVDYFKPGHPQALCVHSYKSMLPEMDRVMEFYKKIRVDGLVKREETPMTMTEYYEGRSDFLAYRHVNFGPRVKKLSQSSVESNPRPMVKITERFSRNPE-KPADEDVAERLFLIVEERIQLRYHCRDDYITASKREFLRRMEVDSKGNKIIMTPEMCISYEVEPMEHTKKLLYQYETMNQLKNEEKLSRHQAWESELEVLEILKLREEEEEAHTLTISIYDTKRNEKSKEYREAMERVLHEEHLRQVEAQLDYLAPFLAQLPPGEKLTRWQAVRLKDECLSDFKQRLIDKANLIQARFEKETQELQKKQQWYQENQVTLTPEDENLYLSYCSQAMFRIRILEQRLNRHKELAPLKYLALEEKLYKDPRLIDFVKVFV--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IY82-1", "uniprot_id": "DRC7_HUMAN", "id": "Q8IY82-1", "name": "Dynein regulatory complex subunit 7", "aln": "-------------MEVLREKVEEEEEAEREEAAEWAEWAR-MEKMMRPVEVRKEEITLKQETLRDLEKKLS-EIQITVSAELPAFTKDTIDISKLPISYKTNTPKEEHLLQVADNFSRQYSHLCPDRVPLFLHPLNECEVPKFVSTTLRPTLMPYPELYN-WDSCAQFVSDFLTMVPLPDPLKPPSHLYSSTTVLKYQKGNCFDFSTLLCSMLIGSGYDAYCVNGYGSLDLCHMDLTREVCPLTVKPKETIKKEEKV--LPKKYTIKPPRDLCSRFEQEQEVKKQQEIRAQEKKRLREEEERLMEAEKAKPDALHGLRVHSWVLVLSGK------------------REVPENFFIDPFTGHSYSTQDEHFLGIESLWNHKNYWINMQDCWNCCKDLIFDLGDPVRWEYMLLGTDKSQLSLTEEDDSGINDEDD-VENLGKEDEDKSFDMPHSWVEQIEISPEAFETRCPNGKKVIQYKRAKLEKWAPYLNSNGLVSRLTTYEDLQCTNILEIKEWYQNREDMLELKHINKTTDLKTDYFKPGHPQALRVHSYKSMQPEMDRVIEFYETARVDGLMKREETPRTMTEYYQGRPDFLSYRHASFGPRVKKLTLSSAESNPRPIVKITERFFRNPA-KPAEEDVAERVFLVAEERIQLRYHCREDHITASKREFLRRTEVDSKGNKIIMTPDMCISFEVEPMEHTKKLLYQYEAMMHLKREEKLSRHQVWESELEVLEILKLREEEEAAHTLTISIYDTKRNEKSKEYREAMERMMHEEHLRQVETQLDYLAPFLAQLPPGEKLTCWQAVRLKDECLSDFKQRLINKANLIQARFEKETQELQKKQQWYQENQVTLTPEDEDLYLSYCSQAMFRIRILEQRLNRHKELAPLKYLALEEKLYKDPRLGELQKIFA--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PYW2-1", "uniprot_id": "A0A8M9PYW2_DANRE", "id": "A0A8M9PYW2-1", "name": "", "aln": "-------------MEVLPEMESEEDATLTDDEEK--------------------------KGFRELESSLNNNIRLTPDLPHIMKPRTPVDLSRYPSSYKQNSSQETLMLAMAENFRQQFVLLYPDRKALLLSPVNECGVQKFVSTTLRSSLLPYPELYD-WEGCASFVSDYLSLELLDPPFELPKQLSSPTRVLQTQRGTCFEFSMVLCSLLLGAGFNAYCVSGYATKEMCLLDQSRQECPLLKPPKQDNTEEPKK--TVNKYSVKPPRDLYSTFEKHQEEKQQAKVKADAVKKQQEEERLRKEQERPPHDPLLGLRIHSWVLVLSGS------------------REIPENFFIDPLTGKGYSTTNENFVGIESIWNHQNYWVNKQDCSFGCGSMTFDLGDLSKWEYMLCGLTSQSISMISEQKSPREPEDE---EEEEIDELKAFEMPTSWVTKIDIPPPDMEMRYPGGSKILQYRKAKLEKFAPYLLKDGLVTKLTTYKDLECTQPNTIKEWFKHRSDHLEERELHTDSNVTTEHFRPGRSDALKYHRYVTLVPETERQMDFYGHTCTDGLARRIEKQSEMTETFEDRTDFLYYRHIVYGKQIKVIR-AGEALNQRPIKSVEERFHRDPS-KPASKDVAERNFKMSDGKIQVTYHLEDDRIIPAWMNFIKPKAAANSQKGQDFSPEMVSGFQVDPFAKPYNDLQLYKILLELMRDEENVELQIRNSEKEVKSILSSREKEDSNTDLLISIYNTTRNETARRHMEEKERKAKEKQKRQKEKELDLLAPFQARLEQTESLTLKDALQLKRDCLTEFKQQLANKANLIQGRFEKETEELQKKQLWYQKNQLTMSTEDEEDYFKYCSEAMFRIHVLKLRLSRQKERAPQRYLALEETLKRHPKLATDS------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q4V516-1", "uniprot_id": "DRC7_DROME", "id": "Q4V516-1", "name": "Coiled-coil domain-containing protein lobo", "aln": "MPKVLFQKYKKVVSNIDPSRYSAKFKEIDEQRRSQGSESDFADEMEGEFEAEMEEMGSSEFSLSEGEPSLN--IGKIDLSFPETVEEFENSPQCYPPSYYTLSPKERLLLLYAENFRKQLVLSYPKRRAMVLALPNECKVQKFVCTTIRPTAFIYTQLISSVEEIAKFVADFIQYEPLQDPINLPNRLISPETLLRKRKGNSYEMATLLVSMLIGAGHPALVVSGVAREETILNDQLAVPYPYPIVEVEVEEVKPKVEKPGQKYKLRGLPDLKSHLEEDMAEVHRQKEAEEKRIQDEIIRKQMEDLELLAVDRYHYRRSHAWVVIINNAPWSVKPKTTYTDVNGDVVEAPPTAIFIEPSTGFICETGCKQYILVDSIWNEYNYYVCKQKHQRVS-ELRWDLRDTKDWEHMLPGEPPEMRIYKMASDENVADEER------DISEEKHLDCIGSWVERLHIGLADFEQRFPSSEKKIQYKGAIHERFSPYSQRDGKVMQLTIFNNDECTIPKVRYEYYENRSDLMRHVKYTYATDQFEEIFNKGRNDSLKSIEYFSD-PSQQRKVHFFSASRIDSLELMVVEPGSLILHYKDRSDKCWYKEFEFTP------------AGNVLKKVTEKFLKASANDVCSNDIATRTFLFQQNKIVLKFHYTFGALTATVVEFTKPPRPD-YGKELIYDEKLTKIYKANPLDPTRTNLELYRLLCEQLQYEDHLRKNFEKIFEDINNVFDLRKSEKAEPKLKFSIFDPLRNGAARAIRMRQFEEEEELKKEIASKPADFLAPYLVPYKHQEELTPEQSQNAYNACLNDLKSRFVSLLNNLQRHYEDLTSESKSLNRFLNKFENQFNNYDYKRLVQQSKDLELNKRMVQQRLTLTHEESQKKYEVVKNSLLKDPRLNFKKDDLARRASETSK", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . . : :: . : : * .* * . . * ** : :* :* *:** :* *.* .:.* *** * ***.**:*.: : *.:* . : *.**:*:: * *:: *.:* *. :*: ::*..:::: :* *:*:*:*. * *.* . : * * : : * :** :: ** * :*:. : : . . : * * * *:**::: . . * :**:* *. * .::: ::*:**. **:: *. . .: :** * **:** * ... :: . .* * :: *** ::.* :* * *...* :**: * *:::** :* * :** ::: :** *::::*.* :. . :. : *. *: ::* * : *. :* :.*: *.* : ::.*.* *:. : . : .: *:* : . . ..:*:* * * . : :* : :* . : . :* : : .: ::.:*: . . * *. : . . *. . : : :: .::. *:.*. * :**::. ** :: . .* : . . * ***: . *.** :: . **.::*.:: . * :* ::*. *.* :. : : :: : :. * . .. ..: :. :::: **. :* : :* .:::.* :.*:* ", "identical_positions": 162, "similar_positions": 264, "identity": "17.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120406-11", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AB59-1", "uniprot_id": "RHG27_MOUSE", "id": "A2AB59-1", "name": "Rho GTPase-activating protein 27", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAADVEGDVYVLVEHPFEYTG--------KDGRRIAIQPNERYRLLRRSTEHWWHVR-----------REPGGRPFYLPAQYVRELP-ALGDPAPAPQPSVPQQRPAVPEPLAYDYRFVSTP--VGADGSSAEPRGRAS------SLCGP-ARQRTGGQRNSLAPGGPACLYVRPAAPVRPAQSLDDLARGGTAPPAGLLGSAGHFKASSVAGSWVCPR---------------------------------------PLAPSDSENVYEAIPDLRCPPRAESPKQ--------------------VDDPPEPVYANVERQPR------------------ATSPRSAAAPPRLSPVWETHTDTGTGRPYYYNPDTGVTTWESPFETP---------------------------------------------------------EGT-TSPATSRASVGSGESLETEWGQYWDEESRRVFFYNPLTGETAWEDETEELEEDHQEQLEMQPSLSPRSPGQQRPP--------TPETDYPELLASYPE-EDYSPVGSFSDPG----------------PASPLVA----PPGWSCQITPDKQ----MLYTNQFTQEQW----------------------------------------------VRLEDQHGKPYFYNPEDSSVQWELPQVPIPAPRSVR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KSSQDSDTPAQASPPEE----------------------KIKTLDKAGVLHRTKTVDKGKRLRKKHWSTSWTVLEG-----------------------------------------------GVLT---FFKDSKTSAAGGLRQPSK---------------------------------------------LSTPEYTVELKGASLSWAPKDKSSKKNVLELRSR----------------------------------------DGSEYLIQHDSEAIISTWHKAIAEG------------------ISELSADLLQG-EEGEPSSADFGSSERLGSWRE----EDVRQNAASPSLSPGGLESDLSRVRHKLRKFLQRRPTLQSLRDKGYIK---------------------------------DQVFGCALAQLCERERSPVPRFVQQCIRTVEA--RGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGR-------WEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQ---------------------RSRCVRDLVRTLPAPNQDTLRLLIQHLCRVIEHGEQNRMTVQNVAIVFGPTLLRPEMEEASMPMTMVFQNQVVELILHQCADIFPPH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6TLK4-1", "uniprot_id": "RHG27_RAT", "id": "Q6TLK4-1", "name": "Rho GTPase-activating protein 27", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAADVEGDVYVLVEHPFEYTG--------KDGRLIAIQPNERCRLLRRSTEHWWHVR-----------REPGGRPFYLPAQYVRELP-ALGDPVPAPQPSVLQQRPTVPEPLAYDYRFVSTP--VGADGSSAEPRGRAS------SLCGP-ARQRTSGQRNSLAPGGPACLYLRPAAPVRPAQSLDDLARGGTAPPAGLLGSAGHFKASSVAGSWVCPR---------------------------------------PLARSDSENVYEAIPDLRCPPRAKSPKQ--------------------VDEPPEPVYANVERQPQ------------------VTSPRSAAAPPRLSPVWETHTDAGTGRPYYYNPDTGVTTWESPFEAP---------------------------------------------------------EGA-TSPTTSRASVGSGESLETEWGQYWDEESGRVFFYNPLTGETVWEDETEELEDDPEEQLEMQPSLSPRSPGQQRPP--------TPETDYPELLTSYPE-EDYSPVGSFSDLG----------------PTSPLVA----PPGWSCQITPEKQ----MLYTNQFTQEQW----------------------------------------------VRLEDQEGKPYFYNPEDSSVQWELPQVPVPAPRSGR----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KSSQDSDTPAQASPPEE----------------------KIKTLDKAGVLHRTKTVDKGKRLRKKHWNASWTVLEG-----------------------------------------------GVLT---FFKDSKTSAASGLRQPSK---------------------------------------------LSTPEYTVELRGASLSWAPKDKSSKKNVLELRSR----------------------------------------DGSEYLIQHDSEAIISTWHKAIAEG------------------IEELSADLPQR-EEGEPSSADFGSSERLGSWKE----EDVRPNAASPSLNPGSQESDLSRVRHKLRKFLQRRPTLQSLREKGYIK---------------------------------DQVFGCALAQLCERERSPVPRFVQQCIRTVEA--RGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGR-------WEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQ---------------------RSRCVRDLVRTLPAPNHDTLRLLIQHLCRVIEHGEQNRMSVQNVAIVFGPTLLRPEMEEASMPMTMVFQNQVVELILHQCADIFPPH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6ZUM4-1", "uniprot_id": "RHG27_HUMAN", "id": "Q6ZUM4-1", "name": "Rho GTPase-activating protein 27", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAADVVGDVYVLVEHPFEYTG--------KDGRRVAIRPNERYRLLRRSTEHWWHVR-----------REPGGRPFYLPAQYVRELP-ALGNPAAAAPP-GPHPSPAAPEPLAYDYRFVSAAATAGPDGAPEESGGRAS------SLCGP-AQRGAATQRSSLAPGLPACLYLRPAAPVRPAQSLNDLACAAVSPPAGLLGSSGSFKACSVAGSWVCPR---------------------------------------PLARSDSENVYEVIQDLHVPPPEESAEQ--------------------VDDPPEPVYANIERQPR------------------ATSP-GAAAAPLPSPVWETHTDAGTGRPYYYNPDTGVTTWESPFEAA---------------------------------------------------------EGA-ASPATSPASVDSHVSLETEWGQYWDEESRRVFFYNPLTGETAWEDEAEN---EPEEELEMQPGLSPGSPGDPRPP--------TPETDYPESLTSYPE-EDYSPVGSFGEPG----------------PTSPLTT----PPGWSCHVSQDKQ----MLYTNHFTQEQW----------------------------------------------VRLEDPHGKPYFYNPEDSSVRWELPQVPVPAPRSIH----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KSSQDGDTPAQASPPEEKVPAELDEVGSWEEVSPATAAVRTKTLDKAGVLHRTKTADKGKRLRKKHWSASWTVLEG-----------------------------------------------GVLT---FFKDSKTSAAGGLRQPSK---------------------------------------------FSTPEYTVELRGATLSWAPKDKSSRKNVLELRSR----------------------------------------DGSEYLIQHDSEAIISTWHKAIAQG------------------IQELSAELPP--EESESSRVDFGSSERLGSWQEKE--EDARPNAAAPALGPVGLESDLSKVRHKLRKFLQRRPTLQSLREKGYIK---------------------------------DQVFGCALAALCERERSRVPRFVQQCIRAVEA--RGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGR-------WEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQAR---------------------RSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEETSMPMTMVFQNQVVELILQQCADIFPPH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B765-1", "uniprot_id": "A0ACD6B765_DANRE", "id": "A0ACD6B765-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGETGKMTSVHTLGLVLVEFEYEYEG--------RDGHMVCIKPNERYILLAKTNDHWWHVC-----------KDERAKPFYIPAKYVKELPPNIPSPLDYREPPGPDVKPAVPD-LTETRKADEVTIRLRSKGNYHKTENRMSTFGVPLDLHEP-PSYKHGGPSDSLISLSSVSASDSSKQKKRMSHAPNLLFGSHSNLPTELVPDKFRVPSFSPADPLHRPIPAKPVEIPIIKNLNETKPHRTSPELESPIEPESESSSSEPMPSPDSENIYESISDLNIDLSSLTDKEPAGLPDTQTTTSSLPPSIKTDNDPTTALYANVADIKKNIPRSSNSSVSTCSSPGITLSPAPDSISPPSSAEWRVHTDHDSGKEFYYHPATGQSSWSDPRSPQ---------------------------------------------------------PGAGMESVTAPVPASSPPSARSDWEQLLDEATGRHYYYNHASNKTSWTAPEPSAPASSKQGPHSQDKDKERPPPLPEED--------YPKNQHEESHISFQLPKDFQLPQIKRAVI----------------PRAVMDTNKDVPTGWTQSVGTDGK----SVFTSELTHEQW----------------------------------------------IQSKDEKGKLYYYSKDGSKCQWTLPEALVPPGQPMNGNGVEQDGPPVLNNWRYTQFNISQE----------------------------------------------------------------------------------------------------------------------------------------DLKFSPSHRRIASDNASDASSSGNSPESQHYDKKFRRRRNLSSYSTDSHSHHSSLEKAGILNKTKVAENGKRLR-KNWAQSWTVLHD-----------------------------------------------GVLT---FHKDPKFAPAG-MSSKTN---------------------------------------------QIVPEYTVELKGATLSWASKEKSSKKNVLELKTR----------------------------------------HGSEYLIQYDTDSIIQDWQKIILDT------------------IKLLHEHGHN----SEDEAEDVPEKSPLPADKE-------KKPEAARLSSTSSIDTDQGRVRTKLRKFLQRRPTLQSVKEKGYIK---------------------------------ENVFGCHLDTLCHRENTTVPKFVEKCIRSVEK--RGLKIDGIYRVSGNLAVIQKLRYKADHEEDLDLEDGQ-------WEEIHVITGALKLFLRELPEPLFPFSFFDKFIAAIQISDYSQ---------------------KVSYIRDLVRNLPLPNHDTMEVLFRHLRKVIEHGEMNRMSVQSTAIVFGPTLLRPQ-EESNITMHMVFQNQIVELVLNEFNELFQTK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P39083-1", "uniprot_id": "RGA1_YEAST", "id": "P39083-1", "name": "Rho-type GTPase-activating protein 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASTAPNEQFPSCVRCKEFITTGHAYELGC--------DRWHTHCFACYKCEKPLSCESDFLVLGTGALICFDCSDSCKNCGKKIDDLAIILSSSNEAYCSDCFKCCKCGENIADLRYAKTKRGLFCLSCHEKLLAKRKYYEEKKRRLKKN-LPSLPTP-VIDNGHTDEVSASAVLPEKTFSRPASLVNEIPSGSEPSKDIETNSSDIVPHFITGYNDSDDNSGSSKFG------------------------------SNVSIDVIGPEENSTEHVNDDVKEEAEAPSANMSLN------------VATDPTLSCKEPPSHSRNLLNKTPLR-----------------NSSGQYLAKSPSSYRQGIIVNDSLEESDQIDPPNNSSRNASELLTSV---------------------------------------------------------LHSPVSVNMKNPKGSNTDIFNTGEISQMDPSLSRKVLNNIVEETNALQRPVVEVVKEDRSVPDLAGVQQEQAEKYSYSN--------NSGKGRKISRSLSRRSKDLMINLKSRATGKQ-------------DSNVKLSPASKVTSRRSQDLMRDNDSHTGLDTPNSNSTSLD----------------------------------------------ILVNNQKSLNYKRFTDNGTLRVTSGKETALEEQKNHSFKSP----------------------------------------------------------------------------------------------------------------------------------------------------------------SPIDHLLQSPATPSNVSMYRTPPLDSSLTFDRRNGSSYSNQNYSIPSWQKTPKTQLENSDNFEEQKETLYENSESRNDPSLDK-----------------------------------------------EIVTAEHYLKQLKINLKELESQREE---------------------------------------------LMKEITEMKSMKEALRRHIESYNSEKNKLYLDSNELSNNPPMINEI---------------------------SLGESPPVKHVATASSVARSSVKPKF------------------WKFFSSAKPQT-EQSIQGVSTNNTNSIVKSAPVLLSAPSSGSNSGRLEISPPVLQNPNEFSDVRLVPIENDANMGQSKDGEEYLDG--------------------------------SNLYGSSLVARCNYENNEIPMILSVCIDFIESDEENMRSEGIYRKSGSQLVIEEIEKQFSAWKVQQNTETPNIL---TEQDLNVVTGVLKRYLRKLPNPIFTFQIYEPLMRLVKSKKMMENLPFVGGKLSLEAKNSDTYMSSKSALKNILEDLPREHYRVLRVLSEHIEKVTRYSHWNRMTLYNLALVFAPGLIRDFSGEKDI-IDMKERNYIVAFIFGNYKDILT--", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q06407-1", "uniprot_id": "RGA2_YEAST", "id": "Q06407-1", "name": "Rho-type GTPase-activating protein 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSADPINDQSSLCVRCNKSIASSQVYELES--------KKWHDQCFTCYKCDKKLNADSDFLVLDIGTLICYDCSDKCTNCGDKIDDTAIILPSSNEAYCSNCFRCCRCSNRIKNLKYAKTKRGLCCMDCHEKLLRKKQLLLENQTKNSSKEDFPIKLP-ERSVKRPLSPTRINGKSDVSTNNTAISKNLVSSNEDQQLTPQVLVSQERDESSLNDNNDNDNSKDREETS----------------------------SHARTVSIDDILNSTLEHDSNSIEEQSLVDNEDYINKMG-----------EDVTYRLLKPQRANRDSIVVKDPRIPNS--------------NSNANRFFSIYDKEETDKDDTDNKENEIIVNTPRNSTDKITSPLNSP---------------------------------------------------------MAVQMNEEVEPPHGLALTLSEATKENNKSSQGIQTSTSKSMNHVSPITRTDTVEMKTSTSSSTLRLSDNGSFSRPQTADNLLPHKKVAPSPNKKLSRSFSLKSKNFVHNLKSKTSEML-------------DPKHPHHSTSIQESDTHSGWGVSST---HTNIRKSKAKKNP----------------------------------------------VSRGQSDSTIYNTLPQHGNFTVPEFNHKKAQSSLGSISKKQNSNDTATN--------------------------------------------------------------------------------------------------------------------------------------------------------RRINGSFTSSSSGHHIAMFRTPPLESGPLFKRPSLSSES-------AHHRSSSLQTSRSTNALLEDDSTKVDATDESATSLEK-----------------------------------------------DFYFTELTLRKLKLDVRELEGTKKK---------------------------------------------LLQDVENLRLAKERLLNDVDNLTREKDKQSASSR-----------------------------------------ESLEQKENIATSITVKSPSSNSDR------------------KGSISNASPKPRFWKIFSSAKDHQVGDLESQQR----SPNSSSGGTTNIAQKEISSPKLIRVHDELPSPGKVPLSPSPKRLDYTPD-------------------------------GSHLYGSSLQARCAYEKSTVPIIIRCCIDRIEKDDIGLNMEGLYRKSGSQTLVEEIENEFAQNNSLHSDTLSPKLNALLNQDIHAVASVLKRYLRKLPDPVLSFSIYDALIDLVRNNQLIERLPLNNDKFLDSPQKVTIYEMVLKSLLEIFKILPVEHQEVLKVLAAHIGKVRRCSERNLMNLHNLSLVFAPSLIHDFDGEKDI-VDMKERNYIVEFILGNYRDIFKQA", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P39960-1", "uniprot_id": "BEM2_YEAST", "id": "P39960-1", "name": "GTPase-activating protein BEM2/IPL2", "aln": "MKGLLWSKNRKSSTASASSSSTSTSHKTTTASTASSSSPSSSSQTIRNSTSGASPYMHSHHHHGQGHSHHRGEDNNRDKRKSSVFPPSKQYTSTSSSQVNLGMYHSDTNTRSSRSIASTLKDDSPSVCSEDEISNSSSQKSNAQDETPIAYKKSAHSKDSLLPSRSSSLSPPQSRCSTGTTLEKSLNTSGISNSSGTNNNNSNNNNDNEQKQRNVIHLNSENYDTTVFKTGWVNKSHGQTVATNYNSSMTAPSSSSSSSSQNLRNDAYSRNRESRFYGNDGSSLKNDDSSSTTATNSGNDVASARSSMAIDPQMLVPDYRLYRAQLKGCVLNLYKSGLNSNIKFFDPTLPASNSSIANENHQQKKQQTNNQAQAEALHQKQSFGQMGEPITLDLKYLSEVYPHPDLRQDSDGKIISGTIESLCHTVLFYPGPKQSDVPNEKSLSKTHRAVINLLLMFPLLDHFIKFLKVFNQFGLSFTKNKSRLTNNSTQFYNISPAVDDSMTQRLALTAKTILDVFPGFLLDEPMLKTIISLLDTISLHNDEISNNLKIKIANKHNELMKLTAFTRSLPMATSSTHELEIILDPSHFLSLDITTLADEVHHINLKFDKVWAPKFDYSLLYDSKFINRRIVSLNPLVFNNDQNIHFLGRLLISHLFPTNPEFSKKVTPKVRAELLDKWVQIGCRFEHLGDMVSWLAVATIICSIPVLRSSSWKYVPDQSLKTIFKDWVPTIIQLERRQRTSKSTSSVFILAPPN-----LDDDFTRANVISYFGDLLIHADDLPSDTKFKYLEKKINRTKNAFHKWQQRLQAIDSTRHKTNSTENVRDNDSPNNVVYQLWKFHLSQPPLNIEGIMKLSVQHEPPIIDQKAYSTIGSQRSALVTGSYLPILFNELFPNYSLFPKNTLVGAASDAKLPPP---------------------RSSARLSKSLSISEPIPIASNSHTMGSLTDDAMSSKNDNNKVTG-------VGKIDGPVIKEMSSKQSNKQRLLKSVRDVFNIDMDVFHISDELVFKSVYDNDGKSRPASMVIETPKRFSQHSSMLINNPATPNQKMRDSLDTTGRLSKTLENMDFFNNIGQVSDSLKESIIRVVLKSSSLEKIFDLLVLTSNIFSKLVDTKDLENYYYHQRQRGHSTRGLSDDNIGLLDYAFVKLTMDNDIFTETFFNTYKSFTTTTTVLENMAKRYVGAKSCSVSISKILDRSDDSKMKINEDTNLVSSSLYDQNFPVWDMKVTDDENINLIYMAKIQIGAAEAILHLVKNHYSDFTDDLCNNSTLLDIIKIMEQEVSTEWPTRIANSKLQKSLPENFVIETENLLTTLTDLFHGIKSAYQKQLYRPIGVNRTQKRITDILNSFNTFSFTDLNNIIDDPSFSDDMIRSFQKLHSTNYEDILEWIYQLDNFISKKFNLVSKKDWIVLFQELELLSKESLVSFFNYPLHFKSSKLINPGYLQLHEFEISNLFTWISTLILKDDNGTESLFFEKLPQSIKLLIKLHTSLTTFFVMEISNVNKSSSERLTTCKVILQILNYIRWKNGSLDLFDSEEDESPHAICPHIPAFIETAIAHAIISPESRNYELSWIKASEKLSDPTKGTQNLRSISNVLEKIDDIHIKRFIEIDDVFSKNCKNLCPCPGWFISRLLEISQFVPNMSITNSKLINFDKRRFVNNIISNVLDLIPNEREFPLDIEMSDENPSKRTTFGRILFNNFEDVNKVYRKKTKKVSESEAISERFQEQGVFNEILVNEIEKIKREARKLEVLLDQEKILKNSAALHQAVPKKNRKSVIISGTHSDNDHSYNINKNTGQTPSLGSVMESNNSARNRRDSRASFSTNRSSVVSNSSHNGVSKKIGGFFRRPFSIGGFNTSSSNYSLNSILSQEVSSNKSILPSILPEVDSMQLHDLKPSYSLKTFEIKSIMEIINHRNIPAYYYAFKIVMQNGHEYLIQTASSSDLTEWIKMIKASKRFSFHSKKYKGKTHNKIFGVPLEDVCERENTLIPTIVVKLLEEIELR--GLDEVGLYRIPGSIGSINALKNAFDEEGATDNSFTLEDD---RWFEVNAIAGCFKMYLRELPDSLFSHAMVNDFTDLAIKYKAHAMVN----------------EEYKRMMNELLQKLPTCYYQTLKRIVFHLNKVHQHVVNNKMDASNLAIVFSMSFINQEDLANSMGSRLGAVQTILQDFIKNPNDYFKQ-", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "X2JCF3-1", "uniprot_id": "X2JCF3_DROME", "id": "X2JCF3-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQTTTSQRPVTPGTPDSAHIVIGAAGFVAHERRQPGKTLMNCFRDRS---------------------------------------TTSSSSSQAQHAYVRGHSVTSSTLFRLE-----------------------------------------------------------GSGGSNCTLDKAGKQDTGRPEAVVLLRELKTRPNKLALLKSSS-------------------------------------------------------------------------------------SKDLTRLFLDDSTNTAVLVSNTSIDVCSSNSSSGGSPAVGRSKSGRDRRNG-------------LECCSSCSKRWHDLKQRMHT------------------------LEQDLLVQTTYSQELEQKVG-----EMSRQLTELLQ-----------------------------------------------ERDRERDKDKARFAAAGGVAAPGKRTAHGSPNVRP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SRLVAWMNLSNWFKSRPSVETLREQRIFFDEPCFDT---------------------------------------------------------ELEMVLKHDQHRTVP---------------------------------------------------RIVVDCCDLIEQKYRRSTQPIEGIYRQC-----------------------------------------GDYNKIQTLRFSIDANDYDSLRQP------------------------------------------------------DVDIHTLTGVLKLFLREIKSPLVRVNEAKTFIGQPNQWLLTDLSAKLDS------------------------------------LKRLIRSLPESNRDTMDYIFGHFNRITKVPLQQISAETLS-ISVTPSIFHTVPQGVHMQDIQQLLREG--------ETLADCVKLMIEYQGRIFDRLRLIQTAHLLCRCVERFANHS-------------------------KSEILNPKPN-----TPLYLPHLYTHSRFAPESVSNPD--HIVYRCTADRRRLSMRNLKKTLSQPDLLFHNLF----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . . : . . . . : . .: . . . . : . . . : . : * . . . : . . .. : :. : :. : : : . . .. : . : . : : .: : : : ::.. * *: . . :*: . .: : : :. .: ", "identical_positions": 4, "similar_positions": 74, "identity": "0.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120406-12", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5JU00-1", "uniprot_id": "DRC5_HUMAN", "id": "Q5JU00-1", "name": "Dynein regulatory complex subunit 5", "aln": "MQDTVTTSALLDPSHSSVSTQDNSSTGGHTSSTSPQLSKPSITPVPAKSRNPHPRANIRRMRRIIAEDPEWSLAIVPLLTELCIQHIIRNFQKNPILKQMLP-EHQQKVLNHLSPDLPLAVTANLIDSENYWLRCCMHRWPVCHVAHHGG--SWKRMFFERHLENLLKHFIPGTTDP-AVILDLLPLCRNYVRRVHVDQFLPPVQLPAQLRPGDQSDSGSEGEMEEPTVDHYQLGDLVAGLSHLEELDLVYDVKDCGMNFEWNLFLFTYRDCLSLAAAIKACHTLKIFKLTRSKVDDDKARIIIRSLLD-HPVLEELDLSQNLIGDRGARGAAKLLSH---SRLRVLNLANNQVRAPGAQSLAHALAHNTNLISLNLRLNCIEDEGGQALAHALQTNKCLTTLHLGGNELSEPTATLLSQVLAINTTLTSINLSCNHIGLDGGKQLLEGMSDNKTLLEFDLRLSDVAQESEYLIGQALYANREAARQRALNPSHFMSTITANGPENSVG-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A6H639-1", "uniprot_id": "DRC5_MOUSE", "id": "A6H639-1", "name": "Dynein regulatory complex subunit 5", "aln": "MQETPSVPSNSSSHSQSVLTIQRQVSALGSSSTGPTSLKTSSTPTPGQLKTKVP--NVRRMRRIISEDAEWSLAIVPLLTELCIQHIVKNFQNNPILKQLPL-EHQKKVLSNLPPELPLTVTANLIDDENYWHRCCIKRWSVCHVSRHGG--SWKRMFFERHLENLLKLFIPGTTDP-NVILDLLPLCRNYVRRIHVDQFLPPVRMPTPLQGEEQSDSGSEGEGSEPEKDHYQLQTLVGGLKHLEELDLVYGVKDCGMNFEWNLFLFTYRDCYSLAATIKACHTLKIFKLTRSKVDDDKARILIRSLLD-HPALEELDLSHNLIGDRGARAAAKLLSH---SRLRVLNLANNQLQAPGAQSLAHALAHNTNLVFLNLRLNCIEDEGGQAIAHALETNKCLSVLHLGGNKLSEPTATLLSQMLTVNTTLVSLNLSCNHIGQDGGKQLLEGISDNKTILEFDLRLSDVSQESEYLIGQVLHANREAARQRTLNPGHFSS-PTNNCTENSVV-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32T7G7-1", "uniprot_id": "A0AB32T7G7_DANRE", "id": "A0AB32T7G7-1", "name": "", "aln": "-------------MAASNFPEEQKVFSSMSRSQSSQRSGVMNSASDGQKR-----------RSIIAEDHEWSLALVPLLTTLCLQHIIKHFEEKPILHELQP-SFKTYVLQRLPASLPLTITANLISDESYWKRCCEARWGLADISTYDN--SWKQMFFERHLQSIIELFIPDTTDT-KTVLDVLPLCQNYVKQLRVSQLLPPIKEPSRFDEDDGSESASDMGSDGPSMDHFDFRMLLDKLPNLKELSVVYCVKGCGMNFEWNLFEFTFRDCESLAKALNSCKTLQVFRIHRSKVDDEKCCVIVNHLLD-HPSLQELDFSHNHISDRGARAIAKLLNR---SQLKTLIVCNNQIRGAGAQALAHALAKNNTLTSLNLRLNRIADEGGQALAQALIKNKTLVNLHLGGNNMTEPAAVALSQALVENCALKSLNLCNNRLGADGGKVLEEGMTHNCTLVECDIRLTDVDQDSEYSICQALHANQIKTKH-------------NHDPSAKV--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VEH4-1", "uniprot_id": "Q9VEH4_DROME", "id": "Q9VEH4-1", "name": "Dynein regulatory complex subunit 5", "aln": "------MDFTYCEFPSTVSIDTFKAYFNLTDVKLPKVGDKSVDT-----------------IQIPSEDQEDQTNQAKSLRHLVLDSIVENWSELPLYRQLGRREDRNYLLSHLDTQLPLQLLSAHIREDFFWQRCYGHRWRSAPLQARGRERPWINIYMERHVQEFIENMPTGDYEQDGNVQVVLDICAAYINQLEISFLQP---APPTTDAN----------------DHIPLDYLLSNLPDLRQLRLSYSTKTVGCNYQMGCNQLTVRDILHLTKGLSQCHELRTFCLHNTKLMPYQLRFLAHSLDKGCHHLTEMSLLHCAVGDAGIRCFLETCGKESFGTLTVLDLTNNKITEEGAYILSRTLRHVP-LEKLVLRLNPIQSDGAAAIFNTLQVMP-IKELDLGTCGITETITKLFMMLICQHTSLLEIDLSNNSLGEDFGKHLMKIISCNKLLERLDLRNTGLSLDMRRKFQEFLLKNVDRKKHEALKQKQ------RDKFKAMMQL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : . . * :** * . . * * :: *:.::.: *: ::: . : :*..* ..*** : : * .: :* ** ** . : . .* .:::***::.::: : .. : : :* :* *:.::.:. : * *. ** : *: * .*.:* : * .* * *:: . :* ** *: :. *: *: * : .:*: : .: . * . * *:.: : :.* * * : .: . * .* : **:: ** *:::* : * * **** * .:*. *: ::* : *.** ::*. : : : : :* .::*. * :* * ** * : :: * : . *:* :.: : . : : * * :: . . : ", "identical_positions": 87, "similar_positions": 144, "identity": "17.06%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120406-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5T764-1", "uniprot_id": "IFT1B_HUMAN", "id": "Q5T764-1", "name": "Protein IFIT1 homolog B", "aln": "-----------------------------------------------------MSEESDGKLIEDSLIQLRCHFTWKLLIEAPEIPDLENRIWEEI--QFLDTKYNVGIHNLLAYVKHLKGQNEEALVSLKKAEDLIQKEHANQADIRSLVTWGNFAWVYYHMGRLAEAQTYLDKVENTCKKFANPSRYRMECPEVDCEEGWALAKCGGKNYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTASGRNKAFSLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAE----GEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAQMIQIKEATNWQPRGQDRETVDRLVQLAICKFEKTIMLKRTFEMAYVDLAETYAEIGHHRKAEEHFQKGLRMK-IFEDQLKQEIHYHYGRFQEHHGKSQDKAITHYLKGLKIEKMSHSREKLLNALEKLAKRCIHQNVRVVESVSLLGLIHKLKGEVSDALLCYERALR--------LAADLNPIF------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P09914-1", "uniprot_id": "IFIT1_HUMAN", "id": "P09914-1", "name": "Antiviral innate immune response effector IFIT1", "aln": "-----------------------------------------------------MSTNGDDHQVKDSLEQLRCHFTWELSIDDDEMPDLENRVLDQI--EFLDTKYSVGIHNLLAYVKHLKGQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAE----GEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVLLHHQIGLCYKAQMIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRKAEENFQKLLCMK-PVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKIEQASLTRDKSINSLKKLVLRKLRRKALDLESLSLLGFVYKLEGNMNEALEYYERALR--------LAADFENSVRQGP--------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ABK0LTN5-1", "uniprot_id": "A0ABK0LTN5_RAT", "id": "A0ABK0LTN5-1", "name": "", "aln": "--------------------------------------------MER-------SEESRRNLIHDSLVELRCHFTWELVIKDNYMPDLEAKILET---EFLDTNYNMGMHNLMAYVRHLKGEQEEALQSLKEAEALIEGE---QLGKRSLVTWGNCAWVHYHRGSLAEAQIYLDKVENVCREFASPFRYRMECAEIDCEEGWALLKCGGSNCTRAMACFAKALQEEPENPEYNAGYAITAFRMD------FSN-EISLEPLRKAVRLNPEDPHLKVLLALKLQDLGKQDE----AEKHIEEALPKIPSRNNIFGYVAKFYRRKGCVEEALEFLERALKTKPSSVYLHFQIGLCHKSRVFQIKEATNMHPKGKDRERADQSIRSAIYYFEKTLDLKPTYERAYIDLAEMYAESKQFEEAEEAFQKVLSMLSNLEVHMQQEIHFRYGKFQQFHMKSENIAITHYLKGLKIEVTSIFRDKLLKALQKLAERRMQQNVHVLESLSLLGFVYRLKGDTRKAMSCYEKALR--------LTEELNPEF------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "D3Z6F0-1", "uniprot_id": "D3Z6F0_MOUSE", "id": "D3Z6F0-1", "name": "", "aln": "--------------------------------------------MEQLLSPSNMSAKSHSCLIYDSLVELRCHFTWKLVIEKVDMPDLEVRISET---EFFDASYSIGMHNLLAYVRHLKGQQEEALQSLKEAEALIQSE---QLSKRRLVTWGNCAWLHYHRGSLAEAQVYLDKVEKVCKEFSSPFQYRLECAEMDCEEGWALLKCGIQNYKGAMACFAKALKVEPENPEYNAGYAVVAYRLD------HID-GTSLQHLQKAVSVKPEDPYLKVLLALKLQDLHKLEE----AEKHIEETLPRISSQPYVFGYVAKFYRRKGLVKEALEFLGRALQKQPCSTFLHFQIGLCHKKRLIQIKKASNMQPRGEDRKRADQSIHLAICHFKRTLELKPTYVMAYVTLAEMYIEKNQLKEAEDNFQKLLNMS-NLEDHIQQEIHFRYGNFQQYYKKSEEAAITHYLKGLKIEVTSHYRDKPLKALEKLAKRRKED--HVLENLGLLGFVYKLKGNTSEAMSCYERALR--------LTGAVNPEF------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64282-1", "uniprot_id": "IFIT1_MOUSE", "id": "Q64282-1", "name": "Antiviral innate immune response effector IFIT1", "aln": "-----------------------------------------------------MGENADGDQVMENLLQLRCHFTWKLLFENNDIPDLEVRISEQV--QFLDIKNPLGMHNLLAYVRHLKGQQDEALQSLKEAEALIQSE---QLSKRSLATWGNCAWLHYHRGSLAEAQIYLDKVEKVCKEFSSPFRYRLECAEMDCEEGWALLKCGGGNYKQAMACFAKALKVEPENPEYNTGYAVVAYRQD------LDDNFISLEPLRKAVRLNPEDPYLKVLLALKLQDLGEHVE----AEAHIEEALSSTSCQSYVIRYAAKYFRRKHRVDKALHLLNRALQASPSSGYLHYQKGLCYKQQISQLRTSRNRQPRRQD--NVQELAQQAIHEFQETLKLRPTFEMAYVCMAEVQAEIHQYEEAERNFQKALNNK-TLVAHIEQDIHLRYGRFLQFHKQSEDKAITLYLKGLKVEEKSFAWRKLLTALEKVAERRVCQNVHLVESTSLLGLVYKLKGQEKNALFYYEKALR--------LTGEMNPAF------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13325-1", "uniprot_id": "IFIT5_HUMAN", "id": "Q13325-1", "name": "Interferon-induced protein with tetratricopeptide repeats 5", "aln": "------------------------------------------------------MSEIRKDTLKAILLELECHFTWNLLKEDIDLFEVEDTIGQQL--EFLTTKSRLALYNLLAYVKHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDD-SDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAE----GEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLE-NITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQK--------IDPENAEFLTALCELRLSI--------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F7EKC1-1", "uniprot_id": "F7EKC1_RAT", "id": "F7EKC1-1", "name": "", "aln": "-----------------------------------------------MEGASGGSSTASKESLESSLQQLKCHFTWNLRAEDESLDEFEDRVFNKD--EFQNSEFKATMCNLLAYVKHCRGLNEAALKCLGEAEDFIRQQHPDQIEIKSLVTWGNYAWVYYHMGQLSKAQEYLDKVKQVCKKFSSP--YRIENPVLDCEEGWARLKCTKNQNERMKVCFEKALEKDPKNPESTSGWAIANYRLDD-----WPASNDYIDSLEQAISLSPDNTYVKVLLAMKLEEVHENR-----AKELVEEALKKDPSAIDTMLGAAKFYVKVHDTDRAIQLLKKALESMPNNAYVHYYLGCCYRSKVLHILNTEE-TTSNGNREKLEALIQPALNHLRKAEDIKEMIENSCSHLAGLYVTTKQYEEADYYFQKEFNKD--LRPLPKQLLHLRYGNFQFYERKCEDRAIYHYMEGVKINRESKPKGKMRDKLRKLALRRLSRDESDPEALRILAFLRE-HREGQGADKASEGEE---------DPGNRVPSASLE---------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q64112-1", "uniprot_id": "IFIT2_MOUSE", "id": "Q64112-1", "name": "Interferon-induced protein with tetratricopeptide repeats 2", "aln": "------------------------------------------------------MSTTSKESLVCNLRQLKCHFTWNLIAEDESLDEFEDRVFNKD--EFQNSEFKATMCNILAYVKHCRGLNEAALQCLGEAEGFIQQQHPDQVEIRSLVTWGNYAWVYYHMGQFSKAQAYLDKVKQVCKKFSSP--YRIENPALDCEEGWARLKCTKNQNERVKVCFQKALEKDPKNPEFTSGWAIAFYRLDD-----WPARNYCIDSLEQAIQLSPDNTYVKVLLALKLDAVHVHKNQ---AMALVEEALKKDPSAIDTLLRAARFYCKVYDTDRAIQLLRKALEKLPNNAYVHYYMGCCYRSKVHHMLNRRE-MVFSGDRKKLEELIQLAVNHLRKAEEIKEMLEYSCSFLADLYIIAKKYDEADYYFQKELSKD--LPPGPKQLLHLRYGNFQFFQMKRQDKAIYHYMEGVKIKKKTIPQKKMREKLQRIALRRLHEDESDSEALHILAFLQE-NGGGQQADKDSERGV---------DSANQVPSASLDEDGAEY---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P09913-1", "uniprot_id": "IFIT2_HUMAN", "id": "P09913-1", "name": "Interferon-induced protein with tetratricopeptide repeats 2", "aln": "------------------------------------------------------MSENNKNSLESSLRQLKCHFTWNLMEGENSLDDFEDKVFYRT--EFQNREFKATMCNLLAYLKHLKGQNEAALECLRKAEELIQQEHADQAEIRSLVTWGNYAWVYYHMGRLSDVQIYVDKVKHVCEKFSSP--YRIESPELDCEEGWTRLKCGGNQNERAKVCFEKALEKKPKNPEFTSGLAIASYRLDN-----WPPSQNAIDPLRQAIRLNPDNQYLKVLLALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKALEYIPNNAYLHCQIGCCYRAKVFQVMNLRE-NGMYGKR-KLLELIGHAVAHLKKADEANDNLFRVCSILASLHALADQYEDAEYYFQKEFSKE--LTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQKSREKEKMKDKLQKIAKMRLSKNGADSEALHVLAFLQELNEKMQQADEDSERGL---------ESGSLIPSASSWNGE------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q64345-1", "uniprot_id": "IFIT3_MOUSE", "id": "Q64345-1", "name": "Interferon-induced protein with tetratricopeptide repeats 3", "aln": "------------------------------------------------------MSEVNRESLEAILPQLKCHFTWNLFREGSMSSHMEDRVCNQV--EHLNSEEKATMYDLLAYIKHLDGESKAALECLGQAEDLRKSEHNDQSEIRRLVTWGNYAWIYYHMGRLSEAQAYVDKVRQVCQKFANP--YSMECPELECEEGWTRLKCG--RNERAKMCFEKALEEKPKDPECSSGMAIAMFRLEE-----KPEKQFSVDALKQAMELNPQNQYLKVLLALKLLRMGEEAE----GERLIKDALGKAPNQTDVLQKAAQFYKKKGNLDRAIELLGKALRSTVNNSPLYSLVMCRYREILEQLQNKGD-ADSSERRQRMAELRRLTMEFMQKTLQRRRSPLNSYSDLI-------DFPEVERCYQMVISKE--SPDVEEEDLYERYCNLQEYHRKSEDLAALECLLQFPRNERSIEKEEVKEQT------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PV48-1", "uniprot_id": "E9PV48_MOUSE", "id": "E9PV48-1", "name": "", "aln": "------------------------------------------------------MSEVNRESLEAILPQLKCHFTWNLFREGSMSSHMEDRVCNQL--EHLNSEEKATMYDLLAYIKHLDGESKAALECLGQAEDLRKSEHKDQAEIRRLVTWGNYAWIYYHMGRLSEAQAYVDKVRQVCQKFANP--YSMECPELECEEGWTRLKCG--RNERAKMCFEKALEEKPKDPECSSGMAIAMFRLEE-----KPEKQFSVDALKQAMELNPQNQYVKVLLALKLLRMGEEAE----GERLIKDALGKAPNQTDVLQKAAQFYKKKGNLDRAIELLGKALRSTVNNSPLYSLVMCRYREILEQLQNKGD-ADSSERRQRMAELRRLTMEFMQKTLQRRRSPLNSYSDLI-------DFPEVERCYQMVISKE--SPDVEEEDLYERYCNLQEYHRKSEDLAALECLLQFPRNERSIEKEEVKQQT------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ABK0M1M6-1", "uniprot_id": "A0ABK0M1M6_RAT", "id": "A0ABK0M1M6-1", "name": "", "aln": "MWPQKRLSEYPRDFVENLLLLPRCSVTLQEMPPHPLTPRAQSLHKVLCPGHRRSQYEVNKESLEKILPQLKCHFTWNLFKEGSISSHMEDRVCNQI--ENLNSEHKATMYDLLAYIKHLDGENEAALECLGQAEDLRKSERSDRAEIKCLVTWGNYAWIYYRIGQLSEAQAYADKVRQVCQKFANP--YSMECPELDCEEGWTRLKCG--RNERAKMCFEKALEEKPEDPECRAGMAIAMYRLQE-----KPEKQFSVDALKQAMELNSQNQYEKVLLALKLQKMGEEAE----AERLVEDALEKGPNQTDVLQKAAQFYRKKGNLDRAIEFLGKALRSTANNSPLYSLVMCRYREKLKQLQNTGE-ADKSERRQTMEELRRLTMEYMNKALQRRPSPLNSYSDLI-------DFPEVEKCYQMVFSEE--SPRAEDQELFERYCNLQEYHRKSEGLKALKDLMQFPRPEKSTEKEEVKQQTQNGDLNLQ----------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14879-1", "uniprot_id": "IFIT3_HUMAN", "id": "O14879-1", "name": "Interferon-induced protein with tetratricopeptide repeats 3", "aln": "------------------------------------------------------MSEVTKNSLEKILPQLKCHFTWNLFKEDSVSRDLEDRVCNQI--EFLNTEFKATMYNLLAYIKHLDGNNEAALECLRQAEELIQQEHADQAEIRSLVTWGNYAWVYYHLGRLSDAQIYVDKVKQTCKKFSNP--YSIEYSELDCEEGWTQLKCG--RNERAKVCFEKALEEKPNNPEFSSGLAIAMYHLDN-----HPEKQFSTDVLKQAIELSPDNQYVKVLLGLKLQKMNKEAE----GEQFVEEALEKSPCQTDVLRSAAKFYRRKGDLDKAIELFQRVLESTPNNGYLYHQIGCCYKAKVRQMQNTGE-SEASGNKEMIEALKQYAMDYSNKALEKGLNPLNAYSDLA-------EFLETE-CYQTPFNKE--VPDAEKQQSHQRYCNLQKYNGKSEDTAVQHGLEGLSISKKSTDKEEIKDQPQNVSENLLPQNAPN--YWYLQGLIHKQNGDLLQAAKCYEKELGRLLRDAPSGIGSIFLSASELEDGSEEMGQGAVSSSPRELLSNSEQLN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1NUT8-1", "uniprot_id": "A0A8M1NUT8_DANRE", "id": "A0A8M1NUT8-1", "name": "", "aln": "----------------------------------------------------MSEMSLIQASLKKKLDQLECHFTWDITKDHLDFTNLLNRLEEQNKLDLGNEEGAARAQCSMGYLKFLLNCKEEALTHLSRSEALIKENFADNNDKALIVTYGNFAWINYHMENYTECESYLVKLQKIHERFATES---SAVPEVLGEKGWTYLKFSRKYYDKAVEVFQKAVELDPTNSEWNAGYAIALYRTENFNPPPCTVETPAIKQLRQAIDLNPDDDVLRVILGIKLLNCSKGLMN--ESEQLVEKALNQSPEHPHVIRYVGMFLRDQGSVDRSIEILKKALQRSPKSGFICHQLAMCYKTKKINLCKEKR------RKVEVDEARDQSIYYLEEATSLIPSFISAVCQLGLQYGDRRDLLKAEEQFDKAFKLVK-EKNEHLQSVHLSYAQFQQYSNRREDLAIEHYEKCLTMNPHTPDGNRSAQKLCNIAKKNLKLNPNDWKANEILGLVYNLKGEMFERYGNTPDNEDD------SFLCNLLEVMSL----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :*.*****.: .. : : . :.*::. . .. ** * .:* : . : . :.*:** **: *: . : * *: : ..::. . *:**: * * *.:: .* :.* * *: :: : *.:*: :..:: :*:*.:** . ::. * . : .. : ..::.:: .*. . : :: :: :: . : : . ..: : : . . * .: . : : . : . ", "identical_positions": 39, "similar_positions": 108, "identity": "6.82%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120406-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TBZ3-1", "uniprot_id": "WDR20_HUMAN", "id": "Q8TBZ3-1", "name": "WD repeat-containing protein 20", "aln": "---MATEGGGKEMNEIKTQFTTREGLYKLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQSGNGDRLCFNVGRELYFYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSESLFLVAHSSGNMYLYNVEHTCGTTAPHYQLLKQGESFAVHTCKSKSTRNPLLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSVELHGTMKSYFGGLLCVCWSPDGKYIVTGGEDDLVTVWSFVDCRVIARGHGHKSWVSVVAFDPYTTSVEEGDPMEFSGSDEDFQDLLHFGRDRANSTQSRLSKRNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARTHTNVMNATSPPAGSN--------------GNSVTTPGNSVPPPLPRSNSLPHSAVSNAGSKSSVMDGAIASGVSKFATLSLHDRKERHHEKDHKRNHSMGHISSKSSDKLNLVTKTKTDPAKTLGTPLCPRMEDVPLLEPLICKKIAHERLTVLIFLEDCIVTACQEGFICTWGRPGKVVSFNP------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FA76-1", "uniprot_id": "E7FA76_DANRE", "id": "E7FA76-1", "name": "WD repeat-containing protein 20", "aln": "MSKMAAEGGGKEMNEIKSQFSTREGAYKLLSHSEYSRPNRVPFNSQGSNPVRVSFVNVNDQSGNGERICFNVGRELYFYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVCLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVRWVPGSESLFLVAHSSGSMYLYNVEHTCGTTAPHYQLLKQGESYAVHTCKSKSTRNPLLKWTVGDGALNEFAFSPDGKFLAVVSQDGFLRVFNFDAVELHGTMKSYFGGLLCVCWSPDGKYIVAGGEDDLVTVWSFADCRVIARGHGHKSWVSVVAFDHYTTSVEESEPMEFSGSDEDFQEQLQCGRERANSTQSRLSKRNSTDSRPLSVTYRFGSVGQDTQLCLWDLTEDILFPHLPLSRTRTHTNVMNASAAPAASSSTLIANTANSANGSGSSTNTPGNALPAPLPRSNSLPHSAAGAANSRSS--ENPAAAGVSKFATLSLHERKERHPDKDHKRNHSMGHISSKSSDKLNLLTKTKTDPAKTLGTPLCPRMEDVPLLEPLVCKKIAHERLTVLIFLEDCIVTACQEGFICTWARPGKVGLLSSQTQANSPSGTVV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **:***********:**:**** ****.**************************:*******:*:***************************************************.**************************************:****************.*************************:********************:**************** *************:***************************:************.********************* *******.:************: *: **:*******************:**************************** ****:*********::.**.*. *.*..****::*.************.. *.*:** :.. *:***********:***** :**********************:****************************:*******************************.***** :.. ", "identical_positions": 507, "similar_positions": 49, "identity": "84.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120406-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K124-1", "uniprot_id": "PKHO2_MOUSE", "id": "Q8K124-1", "name": "Pleckstrin homology domain-containing family O member 2", "aln": "MEEESIKEGSEKPRGARTADKAGWIKKSSGGLLGLWKDRYLLLCQAQLLVYENEDEQKCVETVELGSYEKCQDLRTLLKRKHHRFILLRSP--GNKVSDIKFQAPSGEEKESWIKALNEGINRGKNKAFDEVKVDKTCALEHVTRNRVRGGQRRRPPTRIHLKEVASAASDGLSRLDLD---------------------------------------VPDSGPPVFAPLSDISEDQPQEPPR-----------------ALMPPVKPS-----PGPETSAVEDSKETPAGERALTPDSASSGANP-------------ESQEDAETPAKEDSDVKSLPNSTLSEKLK---------------------VSWENPSPEKPSAPESAQLS---SSETPEATP------------------RESKKPPAPPPK-------------------ILSEKMKACMSGVDASGSSQSSEAPETTSPEPTQVSVNGMDDGPESA--LQAMG---------IPGPAPEDAAASPALPFSDLPSQFHPRSSSLGDLLRESPQHPRLPKEK--LYRAQLEVKVASKQTEKLLNQVLGSEPPPVCAESLLSQAVEQLR------------QATQVLQEMRDLGELN-QETPGLVQKRKELVTLYRRSAP----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TD55-1", "uniprot_id": "PKHO2_HUMAN", "id": "Q8TD55-1", "name": "Pleckstrin homology domain-containing family O member 2", "aln": "MEEEGVKEAGEKPRGAQMVDKAGWIKKSSGGLLGFWKDRYLLLCQAQLLVYENEDDQKCVETVELGSYEKCQDLRALLKRK-HRFILLRSP--GNKVSDIKFQAPTGEEKESWIKALNEGINRGKNKAFDEVKVDKSCALEHVTRDRVRGGQRRRPPTRVHLKEVASAASDGLLRLDLD---------------------------------------VPDSGPPVFAPSNHVSEAQPRETPR-----------------PLMPPTKPF-----LAPETTSPGDRVETPVGERAPTPVSASSEVSP-------------ESQEDSETPAEEDSGSEQPPNSVLPDKLK---------------------VSWENPSPQEAPAAESAEPSQAPCSETSEAAP------------------REGGKPPTPPPK-------------------ILSEKLKASMGEMQASGPP---------APGTVQVSVNGMDDSPEPAKPSQAEG---------TPGTPPKDATTSTALPPWDLPPQFHPRCSSLGDLLGEGPRHPLQPRER--LYRAQLEVKVASEQTEKLLNKVLGSEPAPVSAETLLSQAVEQLR------------QATQVLQEMRDLGELS-QEAPGLREKRKELVTLYRRSAP----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5N8-1", "uniprot_id": "A0ACD6B5N8_DANRE", "id": "A0ACD6B5N8-1", "name": "", "aln": "-MEDGVKEEPAKPKEVKSAEKAGWLKKSSGKFLSSYKDRYIQLDRTAIAVYENEELTTCLEKLELDNYETCHELKSAFKKK-HRLVLIRSPKSGNKVQDVKLQAPTPEEKEAWIKALCEGINKAKNKVFDEVKVDESSTLEHVTRDRPKGNRGRRPPTRIHMKEVANVSNDGMLRLDLDGEVTMLNGTHTLNKEGDKQTETSKPAVTLNNIQEEDAEEEPTPQKKVKPPMPPSKDNKPSESIKEDEPKNEEPAPQKNIVTPPMPPSKKSKPSISLESEADSTDYSESTPSNKGVQPPAPPSKHMKPNQQVTPATATVTTDQKETQEKNEEVDDDAGTKVNGALKEKEDQDKPEEVEILILSKQVMKPQVVMWDSPVVVSKDAEKEAKSAKKVSDITKEVTTTTEPQQLNPAPSSTPESVKKSPGPPAPPKKKPIKAPDKKEDTPHQGDQPVLSDSSNVSLNKVSEQSFKKDDPKLTIPDHKTEPVGDVSSEEMEEKSLDSGQHSGEESETGDQVTPSSTKLKGSSQGLDLETSEDDLEPSDSKAESLEDPSLETPSVTPETSVLSAHPTPNQCSNKSMSRTLPLSPSSKGRSASLGDLLSESTERMESKGKPQGSELKVLQSKVSIEIEKTGELLNAIATGQSEDKEEASPEMLLAAAMEKLRKADQFLKEARSFKDPKGSKRLSL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:.:** **: .: .:****:***** :*. :****: * :: : *****: .*:*.:**..**.*::*:: :*:* **::*:*** ****.*:*:***: ****:***** ****:.***.*******::.:******:* :*.: ******:*:****..:.**: ***** * . * .* .: :* *. : . *** * .*: : .** .: . .* ..*. .* :.:* *. : *.. *..* :* . * *:.* . * :.*: : .. * *.:. ::. **:** * :**:. :..:. :. .. . *. . :: * : . . ...: :* .* ::.* *. .* . . * . * * : :.:. .: * .*: ... ***::.*::. ::* *:.. *** :.* :.::* . :*. ", "identical_positions": 158, "similar_positions": 169, "identity": "23.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120406-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49897-1", "uniprot_id": "IOD3_RAT", "id": "P49897-1", "name": "Thyroxine 5-deiodinase", "aln": "MPRQAASRLVVGEGEGPPGASGPAATMLRSLLLHSLRLCAQTASCLVLFPRFLGTAFMLWLLDFLCIRKHFLRRRHPDHPEPEVELNSEGEEMPPDDPPICVSDDNRLCTLASLKAVWHGQKLDFFKQAHEGGPAPNSEVVRPDGFQSQRILDYAQGTRPLVLNFGSCTUPPFMARMSAFQRLVTKYQRDVDFLIIYIEEAHPSDGWVTTDSPYVIPQHRSLEDRVSAARVLQQGAPGCALVLDTMANSSSSAYGAYFERLYVIQSGTIMYQGGRGPDGYQVSELRTWLERYDEQLHGTRPRRL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91ZI8-1", "uniprot_id": "IOD3_MOUSE", "id": "Q91ZI8-1", "name": "Thyroxine 5-deiodinase", "aln": "MPRQAASRLVVGEGEGPPGASGPAATMLRSLLLHSLRLCAQTASCLVLFPRFLGTAFMLWLLDFLCIRKHFLRRRHPDHPEPEVELNSEGEEMPPDDPPICVSDDNRLCTLASLKAVWHGQKLDFFKQAHEGGPAPNSEVVRPDGFQSQRILDYAQGTRPLVLNFGSCTUPPFMARMSAFQRLVTKYQRDVDFLIIYIEEAHPSDGWVTTDSPYVIPQHRSLEDRVSAARVLQQGAPGCALVLDTMANSSSSAYGAYFERLYVIQSGTIMYQGGRGPDGYQVSELRTWLERYDEQLHGTRPHRF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P55073-1", "uniprot_id": "IOD3_HUMAN", "id": "P55073-1", "name": "Thyroxine 5-deiodinase", "aln": "MPRQATSRLVVGEGEGSQGASGPAATMLRSLLLHSLRLCAQTASCLVLFPRFLGTAFMLWLLDFLCIRKHFLGRRRRGQPEPEVELNSEGEEVPPDDPPICVSDDNRLCTLASLKAVWHGQKLDFFKQAHEGGPAPNSEVVLPDGFQSQHILDYAQGNRPLVLNFGSCTUPPFMARMSAFQRLVTKYQRDVDFLIIYIEEAHPSDGWVTTDSPYIIPQHRSLEDRVSAARVLQQGAPGCALVLDTMANSSSSAYGAYFERLYVIQSGTIMYQGGRGPDGYQVSELRTWLERYDEQLHGARPRRV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P485-1", "uniprot_id": "A0A8M1P485_DANRE", "id": "A0A8M1P485-1", "name": "Iodothyronine deiodinase", "aln": "--------------------------------MNTGRALKNALVCLLILPRFLVAAFMLWCLDFLCVRKRVLVHLQERAEE-------EEEDAEEEEEPLCISDSSRMFSWESLKAVFHGHKLDYMKSARLGHAAPDSEVFPLAEPRRGRVLEFARGHRPLVLSFGSCSUPPFMRRLKAFRRLVLRYADVADALLIYIEEAHPSDGWRSSDAPHQIRRHRSLEERLSAARLMEREAPGCAVVADGMENAANSAYGAYFDRLYIVQDGRVVYQGGRGPEGFRISELRHWLDRYRERLRDAVIPV-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: * :: **:::**** :***** *****:**:.* : : * * *: :: *:*:**..*: : *****:**:***::*.*: * .**:***. : ::*::*:* *****.****:***** *:.**:*** :* .* *:************ ::*:*: * :*****:*:****:::: *****:* * * *::.*******:***::*.* ::*******:*:::**** **:** *:*:.: ", "identical_positions": 136, "similar_positions": 76, "identity": "44.74%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120409-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CWY4-1", "uniprot_id": "GEMI7_MOUSE", "id": "Q9CWY4-1", "name": "Gem-associated protein 7", "aln": "MQSPLTIPVPVPVLRLPRGPDGFSRGFASDG-RRTILRPEVGEG----HIQDPPESQEQRARATLRERYLRSLLAMVGHPVSFTLHEGVHVTAQFGATDLDVANFYVSQLQTPIGVQAEALLRCSDIISYSFKL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H840-1", "uniprot_id": "GEMI7_HUMAN", "id": "Q9H840-1", "name": "Gem-associated protein 7", "aln": "MQTPVNIPVP--VLRLPRGPDGFSRGFAPDG-RRAPLRPEVPEIQECPIAQESLESQEQRARAALRERYLRSLLAMVGHQVSFTLHEGVRVAAHFGATDLDVANFYVSQLQTPIGVQAEALLRCSDIISYTFKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1R879-1", "uniprot_id": "F1R879_DANRE", "id": "F1R879-1", "name": "", "aln": "MKTPVG------VLRLPRGPEPNSRGFDPNSPRFQALCPTSLTS---SSSSSSVDVEEQRLRAEQREHFLRTLLLMTDKRVDFQLLEKLRMRGRFGASDIDVLNFQVSDLETPLGVQKEALLRCHDIISCSFEL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::*: ********: **** .:. * * * ... : :*** ** **::**:** *..: *.* * * ::: .:***:*:** ** **:*:**:*** ****** **** :*: ", "identical_positions": 60, "similar_positions": 31, "identity": "44.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120410-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P30937-1", "uniprot_id": "SSR4_RAT", "id": "P30937-1", "name": "Somatostatin receptor type 4", "aln": "------------------------------------------------------------------------------------------MNTPATLPLGGED---TTWTPGINASWAPDEEE-DAVRSDGTGTAG--------MVTIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASAAALRHWPFGAVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAVFADTRPARGGEAVACNLHWPHPA---WSAVFVIYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVTVFVLCWMPFYVVQLLNLFVTSL------DATVNHVSLILSYANSCANPILYGFLSDNFRRSFQR---------------------------------------------VLCLRCCLLETTGGAEEEPLDYYATALKSRGGPGCICPPLPCQQEPMQAEPACKRVPFTKTTTF------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49660-1", "uniprot_id": "SSR4_MOUSE", "id": "P49660-1", "name": "Somatostatin receptor type 4", "aln": "------------------------------------------------------------------------------------------MNAPATLPPGVED---TTWTPGINASWAPDEEEEDAMGSDGTGTAG--------MVTIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASAAALRHWPFGAVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAVFADTRPARGGEAVACNLHWPHPA---WSAVFVIYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVTVFVLCWMPFYVVQLLNLFVTSL------DATVNHVSLILSYANSCANPILYGFLSDNFRRSFQR---------------------------------------------VLCLRCCLLETTGGAEEEPLDYYATALKSRGGAGCICPPLPCQQEPVQAEPGCKQVPFTKTTTF------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P31391-1", "uniprot_id": "SSR4_HUMAN", "id": "P31391-1", "name": "Somatostatin receptor type 4", "aln": "------------------------------------------------------------------------------------------MSAPSTLPPGGEEGLGTAWPSAANASSAPAEAEEAVAGPGDARAAG--------MVAIQCIYALVCLVGLVGNALVIFVILRYAKMKTATNIYLLNLAVADELFMLSVPFVASSAALRHWPFGSVLCRAVLSVDGLNMFTSVFCLTVLSVDRYVAVVHPLRAATYRRPSVAKLINLGVWLASLLVTLPIAIFADTRPARGGQAVACNLQWPHPA---WSAVFVVYTFLLGFLLPVLAIGLCYLLIVGKMRAVALRAGWQQRRRSEKKITRLVLMVVVVFVLCWMPFYVVQLLNLFVTSL------DATVNHVSLILSYANSCANPILYGFLSDNFRRFFQR---------------------------------------------VLCLRCCLLEGAGGAEEEPLDYYATALKSKGGAGCMCPPLPCQQEALQPEPGRKRIPLTRTTTF------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA53EGL8-1", "uniprot_id": "A0AA53EGL8_DANRE", "id": "A0AA53EGL8-1", "name": "", "aln": "------------------------------------------------------------------------------------------MAELAGYS-GNES--------FMLATDLPFNSTGDYEYYESEPDAS--------KIIIPSIYALVCCIGVTGNAMVIYVILKYAKMKTATNIYILNLAIADELFMLSVPFLATSAAVHHWPFGSLMCRLVLSVDGINMFTSIFCLTVLSVDRYIAVVHPIKAARYRRPTVAKVVNVCVWGLSLLVILPIIIFADTVPAQDG-GVDCNFMWPESS---WSEAFVVYTFLLGFLLPVGAICLCYCLIVVRMRAVGLKAGWLQRRRSEKKITRMVLLVVAVFVLCWMPFYIVQLISVFRKPP------DPMVTQLFVILSYANSGANPILYGFVSDNFRRSFQR---------------------------------------------IICFR--WLEN--GLDAEQVDYCAVALRRQTTCGQQDFPKECLASDMVFRNG---TCTSRTTTL------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0S0WMT8-1", "uniprot_id": "A0A0S0WMT8_DROME", "id": "A0A0S0WMT8-1", "name": "", "aln": "MEGGWWRGGGGGGRLGGKAIMEGHSTPNGAAASHRNNSTRTNIATNGCAHSGILLFVLTAMTLTSLITPTEQLAVAPNGTTLHQLESVESESYPSINGTQNETMVTSVRPHLDHRNRPTQQNGSHYLEYDDDGPDCSYSYNFILKLITMILYALVCIIGLFGNTLVIYVVMRFSKMQTVTNIYILNLAIADECFLIGIPFLLYTMQVGNWPFGNYMCKAYMVSTSITSFTSSIFLLIMSADRYIAVCHPISSPRYRTPFVSKLVSAFAWMTSVLLMLPVILFASTVQSSNG-NVSCNIEWPDTQNSHTDSTFILYSLVLGFATPLTFILVFYCLVIRKLHTVGPKHKSKEKKRSHRKVTKLVLTVISAYIFCWLPHWISQVALISSAPQRCASRLELAVFLACGCLSYSNSAMNPILYAFLSDNFKKSFMKACTCAARKDVNAQLQLENSFFPKFGKGRQSERLLGGNGKGGAQRGALTKKKCLATRNNNAPMATTTTTTTTTTGTDAVTCLQPPVHQVPAEIQVGNPATVLVVNAETNNCKPPVLHTDLXDRAPSMPLETVVFIARRXDHQVELDLDTAIDCQAIARQPECLL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * . . : . : :***** :*: **::**:*:::::**:*.****:****:*** *::.:**: : : :**** :*: : .:. *** : * ::*.***:** **: :. ** * *:*::. .* *:*: **: :**.* : .* * **: **.. . .*::*:::*** *: * : * *:: ::::*. : :::**.:*:*::** *: .:::**:*.:: *: : . : * ***:** *****.*:****:: * : : : . :.: * : . *. ", "identical_positions": 105, "similar_positions": 111, "identity": "17.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120410-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACX8-1", "uniprot_id": "PCD16_RAT", "id": "D4ACX8-1", "name": "Protocadherin-16", "aln": "-----------------------MQEELSVALSCP------------GMKS------LGTLLPLLVLLGTTVPGIRGQAGSLDLQIDEEQPAGTLIGDISAGLPPGTAPPPMYFISAQEGSGVGTDLDIDEHSGVVCTARVLDRERRDRYRFTAVTPDGATVEVTVRVADINDHAPAFPQARAALQIPEHTALGTRYPLEPAHDADAGRLGTQGYALSGDGAGETFRLETRPGPGGAPVPELVIAGELDRENRSHYMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQSRYHAVVSESLAPGSPVLQVFASDADAGANGAVTYEINRRQSEGDGPFSIDAHTGFLKLERPLDFEQRRVHELVVQARDGGAHPELGSAFVTVHVRDANDNQPSMTVIFLSADGSPRVSEAAPPGQLVARISVSDPDD-GDFAHVNVSLEGGEGHFALSTQDSVIYLVCVARRLDREERDVYNLRVTATDSGSPPLRAEAAFVLHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARDPDQGTNGQVTYSLAP--GTHTHWFSIDPTSGIITTAATLDYELEPQPQLIVVATDGGLPPLVSSATVSVALQDVNDNEPQFQRTFYNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLGAGLGASGSPPFRIDAHSGEVCTTRILDRDQGPSSFDFTVTAIDGGGLKSMVYVKVFVADENDNPPQFYPREYAASLS-----AQSTPGTAVLRVHAHDPDQGPHGRLSYHILAGNSPPLFALDAHSGLLTVAWP--LGRRANSVVQLEIGAQDGGGLQAEPIARVNISIVPGTPTPPIFEQLQYVFSVPEDVAPGTSVG-VVQAHNPPGRLGPVTLTLSGGDPRGLFSLDSASGLLKTLRPLDRELLGPVLELEVRAGSGTPPVFSAARIRVLLDDVNDNSPAFP-APEDTVLLPQNTAPGTPVYTLRALDPDSGANSRVTFSLLAGGDG-LFTVDPTTGHVRLMGPLGPPGGPPHELEVEAQDGGSPPRTSHFRLRVVIQDLGIHGLAPRFDSPTYRVDLPSGTTTGTQILQVQAQAPDG---------------SPVTYHLAADGASNPFGLESQSGWLWVRAALDRESQELYTLKVMAVSGSKAELGQQTGTATVRVVILNQNDHSPRLSEEPTFLAVAENQPPGTSVGRVFATDKDSGPNGRLTYSLQQLSEDSKAFRIHPQTGEVTTLQTLDREQQSSFQLLVQVQDAGSPPRSATGTVHVAVLDLNDNSPTFLQASGAAGGGLPIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLT----GSGSELFSLHPHTGELHTAASLIRAERPHYVLTLSAHDQGSPPRSASLQLLVQVLPSTRMVESP-DLVEADSAATVPVVLTVTAAEGLRPGSLLGSVAPQEP------------ASMGVLTYTLVGGAD--PEGTFALDSASGRLYLARVLDFESGPAWRALTVRAEGPGGAG--ARLMRVQVRVQDENEHAPAFARDPLALALPENPEPGATLYTFRASDADGPGPNSDVRYRLLRQEPPVP-------ALR-LDARTGALSAPRGLDRETTPALLLIVEATDRPANASRRKATRVSARVFVTDENDNAPVFASP-------SRMRLPEDQPPGPAALHVVARDPDLGEAARVSYRLAAGGD-GHFRLHATTGALSVVRPL-----DREQRAEHVLTVVASDHGSP-PRSSTQLLTVSVVDVNDEAPAFPQQEYNVILRENSPPGTSLLTLKATDPDLGANGQVTYG---GVSGESFSLDPNSGVLTTLRALDREEQEEINLTVYARDRGLPPLLTHITVR-----------------------VTVEDENDHSPTFG-NTHLSLEVPEGQDPQTLTTLRASDPDGGLNGQLQYRILGGDPSGAFALDLTSGEFGTTRPLDREVEPAFQLQIEARDGGQP-ALSATLLVTVTVLDANDHAPAFPVPSYSVEVPEDAPVGTLLLQLQAHDPDEGDNGRVMYYLGAGTAGAFLLEPTSGELSTATALDREHCASYAFSVTAVDGAAAGPLSTTVPITVTVRDVNDHAPAFPTSPLRLRLPRPGPSLNKPTLALATLRAEDRDAGANASILYRLAGT---PPPGTTVDSYTGEIRVARSPAALGPRDRVLFIVATDLGRPARSATGVVIVGIQGEPE--RGPRFPRANNEAVLRENAPPGTPVISPKAVHSGGSNGPITYSILSGNERGIFSIQPSTGTITVQSAEGLDFETNPR--------------------------------------------------LRLVLQAESGGA---FAFSVLTLTLQDANDNAPRFLQPHYVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSLAASQPARGLFHVDPATGTITTTAILDREIWAETRLVLMATDRGSPALVGSATLTVMVIDTNDNRPTIPQPWELRVSEDALLGSEIAQVTGNDVDSGPVLWYVLSP-SGPQDP----FSIGRYGGRVSLTGPLDFEQCDHYHLQLLAHDGPHEGHANLTVLVEDVNDNVPIFSQS---LYQVMMLEHTPPGS------AILSVSATDRDS-GANGHISYHLASPAEGFSVDTNNGTLFTTVGAMALGHEGPGVVDVVLEARDHGAPGRSAQATVHVQLKDQNDHAPSFTLPHYRVAVSEDLPPGSTLLTLEAIDADGSRSHATVDYSIISGNRGRVFQLEPRLAEVGDGVGPGPQALGCLVLLEPLDFESLTQYNLTVTAADRGQP------PRSSAVPVTVTVLDVNDNPPVFTR-ASYRVTVPEDMPVGAELLHVEASDADP--GPHGLVHFTLSSGDPLGLFELDENSGALRLAHPLDCETQAQ-HQLVVQAAD--PAGTHFALVPVTVEVQDVNDHGPAFPLSLLSTSLAENQPPGTLVTTLHAMDGDAGTFGRLRYTLLEAVPGPEGREAFSLNSSTGELRARVPFDYEHTGSFRLLVGAADAGNLSASVTVSVLITGEDEYDPVFLAPSFHFQVPEGAQR--GHSLGHVQATDEDGGADGLVLYSLATSSPYFGINQTTGALYLRVDSRAPGSGTATSGGGGRTRREAPRELRLEVVARGPLPGSRSATVPVTVDITHTALGLAPDLNLLLVGAVAASLGVVVVLALAALVLGLVRARSRK---------AEAAPGPMSQTAPIASSSLQKLGREPPSPPPSE--------HLYHQTLPSYGGPGAG---GPYPRGGSLDPSHSSGRGS--AEAAEDDEIRMINEFPRVASVAS----SLAARGPDSGIQQDADGLS---------------DTSCEP-PAPDTWYKGRKAGLL-------------LPGAGATLYREEGPPATATAFLG-GCGLSPAP-------TGDYGFPA---DGKPCVAGALTAIVAGEEELRGSYNWDYLLSWCPQFQPLASVFTEIARLKDEARP----------------------------CPPAPRIDPPPLITAVAHPGAKSVPPKPASTAATRAIFPPASHRSPISHEGS---LSSAAMSPSFSPSLSPLAARSPVVSPFGVAQGPSASALSTESGLEPPDDTELRI-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E9PVD3-1", "uniprot_id": "PCD16_MOUSE", "id": "E9PVD3-1", "name": "Protocadherin-16", "aln": "-----------------------MQKELSVALSCP------------GMKS------LRTLLPLLVLLGATVPGSWGQAGSLDLQIDEEQPAGTLIGDISAGLPPGTAPPPMYFISAQEGSGVGTDLAIDEHSGVVRTARVLDRERRDRYRFTAVTPDGATVEVTVRVADINDHAPAFPQARAALQIPEHTALGTRYPLEPARDADAGRLGTQGYALSGDGAGETFRLETRPGPGGAPVPELVIAGELDRENRSHYMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQSRYHAVVSESLAPGSPVLQVFASDADAGANGAVTYEINRRQSEGDGPFSIDAHTGFLRLERPLDFEQRRVHELVVQARDGGAHPELGSAFVTVHVRDANDNQPSMTVIFLSADGSPRVSEAAPPGQLVARISVSDPDD-GDFAHVNVSLEGGEGHFALSTQDSVIYLVCVARRLDREERDVYNLRVTATDSGSPPLRAEAAFVLHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARDPDQGTNGQITYSLAP--GTHTHWFSIDPTSGIITTAATLDYELEPQPQLIVVATDGGLPPLVSSATVSVALQDVNDNEPQFQRTFYNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLGAGLGASGSPPFRIDAHSGDVCTTRTLDRDQGPSSFDFTVTAIDGGGLKSMVYVKVFVADENDNPPQFYPREYAASLS-----AQSTPGTAVLRVHAHDPDQGPHGRLSYHILAGNSPPLFALDAHSGLLTVAWP--LGRRANSVVQLEIGAQDGGGLQAEPIARVNISIVPGTPTPPIFEQLQYVFSVPEDVAPGTSVG-IIQAHNPPGRLGPVTLTLSGGDPRGLFSLDSPSGLLKTLRPLDRELLGPVLELEVRAGSGTPPVFAVARIRVLLDDVNDNSPAFP-APEDTVLLPQNTAPGTPIYTLRALDPDSGANSRITFNLLAGGDG-LFTVDPTTGHVRLMGPLGPPGGPAHELEVEARDGGSPPRTSHFRLRVVIQDLGIHGLAPRFDSPTYRVDLPSGTTTGTQILQVQAQAPDG---------------SPVTYHLAADGASSPFGLESQSGWLWVRTALDRESQELYTLKVMAVSGSKAELGQQTGTATVRVIILNQNDHSPRLSEEPTFLAVAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLSEDSKAFRIHPQTGEVTTLQTLDREQQSSFQLLVQVQDGGSPPRSATGTVHVAVLDLNDNSPTFLQASGAAGGGLPIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLT----GPGSELFSLHPHTGELHTAASLVRAERPHYVLTLSAHDQGSPPRSASLQLLVQVLPSTRVVESP-DLIEADSAATVPVVLTVTAAEGLRPGSLLGSVAPQEP------------ASVGVLTYTLVGGAD--PEGTFALDSASGRLYLARPLDFEAGPAWRALTVRAEGPGGAG--ARLLRVQVRVQDENEHAPTFARDPLALALPENPDPGATLYTFRASDADGPGPNSEVRYRLLRQEPPVP-------ALR-LDARTGALSAPRGLDRETTPALLLLVEATDRPANASRRRAARVSARVFVTDENDNAPVFASP-------SRVRLPEDQPPGPAALHVVARDPDLGEAARVSYRLAAGGD-GHFRLHATTGALSVVRPL-----DREQRAEHVLTVVALDHGSP-PRSSTQLLTVSVVDVNDEAPAFPQQEYNVILRENSPPGTSLLTLKATDPDLGANGQVTYG---GVSGESFSLDPNTGVLTTLRALDREEQEEIYLTVYARDRGLPPLLTHITVR-----------------------VTVEDENDHTPTFG-NTHLSLEVPEGQDPQTLTTLRASDPDGGLNGQLQYRILDGDSSGAFALDLTSGEFGTMRPLDREVEPAFQLQIEARDGGQP-ALSATLLVTVTVLDANDHAPVFPVPSYSVEVPEDAPVGTLLLQLQAHDPDDGDNGRVMYYLGAGTAGAFLLEPTSGELSTATALDREHCASYAFSVTAVDGAAAGPLSTTVPITITVRDVNDHAPAFPTSPLRLRLPRPGPSLNKPTLALATLRAEDRDAGANASILYRLAGT---PPPGTTVDSYTGEIRVARSPVALGPQDRVLFIVATDLGRPARSATGVVVVGIQGEPE--RGPRFPRTSSEAVLRENAPPGTPVISPKAVHSGGSNGPITYSILSGNERGIFSIQPSTGAITVRSAEGLDFETSPR--------------------------------------------------LRLVLQAESGGA---FAFSVLTLTLQDANDNAPRFLRPHYVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSLAASQPARGLFHVDPATGTITTTAILDREIWAETRLVLMATDRGSPALVGSATLTVMVIDTNDNRPTIPQPWELRVSEDALLGSEIAQVTGNDVDSGPVLWYVLSP-SGPQDP----FSIGRYGGRVSLTGPLDFEQCDHYHLQLLAHDGPHEGHANLTVLVEDVNDNVPTFSQS---LYQVMMLEHTPPGS------AILSVSATDRDS-GANGHISYHLASPAEGFRVDPNNGTLFTTVGAMALGHEGPGVVDVVLEARDHGAPGRTAQATVHVQLKDQNDHAPSFTLPHYRVAVSEDLPPGSTLLTLEATDADGSRTHATVDYSIISGNRGRVFQLEPRLAEVGDGVGPGPQALGCLVLLEPLDFESLTQYNLTVAAADRGQP------PRSSAVPVTVTVLDVNDNPPVFTR-ASYRVTVPEDMPVGAELLHVEASDADP--GPHGLVHFTLSSGDPLGLFELDENSGALRLSRPLDCETQAQ-HQLVVQAAD--PAGTHFSLVPVTVEVQDVNDHGPAFPLSLLSTSLAENQPPGTLVTTLHAIDGDAGTFGRLRYSLLEAVPGPEGREAFSLNSSTGELRARVPFDYEHTGSFRLLVGAADAGNLSASVTVSVLITGEDEYDPVFLAPSFHFQVPEGAQR--GHSLGHVQATDEDGGADGLVLYSLATSSPYFGINQTTGALYLRVDSRAPGSGTTTSGGGGRTRREAPRELRLEVVARGPLPGSRSATVPVTVDITHTALGLAPDLNLLLVGAVAASLGVVVVLALAALVLGLVRARSRK---------AEAAPGPMSQTAPIASSSLQKLGREPPSPPPSE--------HLYHQTLPSYGGPGAG---GPYPRGGSLDPSHSSGRGS--AEAAEDDEIRMINEFPRVASVAS----SLAARGPDSGIQQDADGLS---------------DTSCEP-PAPDTWYKGRKAGLL-------------LPGAGATLYREEGPPATATAFLG-GCGLSPAP-------AGDYGFPA---DGKPCVAGALTAIVAGEEELRGSYNWDYLLSWCPQFQPLASVFTEIARLKDEARP----------------------------CPPAPRIDPPPLITAVAHPGAKSVPPKPASTAVARAIFPPASHRSPISHEGS---LSSAAMSPSFSPSLSPLAARSPVVSPFGVAQGPSASALSTESGLEPPDDTELRI-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96JQ0-1", "uniprot_id": "PCD16_HUMAN", "id": "Q96JQ0-1", "name": "Protocadherin-16", "aln": "-----------------------MQKELGIVPSCP------------GMKSPRPHLLLPLLLLLLLLLGAGVPGAWGQAGSLDLQIDEEQPAGTLIGDISAGLPAGTAAPLMYFISAQEGSGVGTDLAIDEHSGVVRTARVLDREQRDRYRFTAVTPDGATVEVTVRVADINDHAPAFPQARAALQVPEHTAFGTRYPLEPARDADAGRLGTQGYALSGDGAGETFRLETRPGPDGTPVPELVVTGELDRENRSHYMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQSRYHAVVSESLAPGSPVLQVFASDADAGVNGAVTYEINRRQSEGDGPFSIDAHTGLLQLERPLDFEQRRVHELVVQARDGGAHPELGSAFVTVHVRDANDNQPSMTVIFLSADGSPQVSEAAPPGQLVARISVSDPDD-GDFAHVNVSLEGGEGHFALSTQDSVIYLVCVARRLDREERDAYNLRVTATDSGSPPLRAEAAFVLHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARDPDQGTNGQVTYSLAP--GAHTHWFSIDPTSGIITTAASLDYELEPQPQLIVVATDGGLPPLASSATVSVALQDVNDNEPQFQRTFYNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLGAGLGSSGSPPFRIDAHSGDVCTTRTLDRDQGPSSFDFTVTAVDGGGLKSMVYVKVFLSDENDNPPQFYPREYAASIS-----AQSPPGTAVLRLRAHDPDQGSHGRLSYHILAGNSPPLFTLDEQSGLLTVAWP--LARRANSVVQLEIGAEDGGGLQAEPSARVDISIVPGTPTPPIFEQLQYVFSVPEDVAPGTSVG-IVQAHNPPGRLAPVTLSLSGGDPRGLFSLDAVSGLLQTLRPLDRELLGPVLELEVRAGSGVPPAFAVARVRVLLDDVNDNSPAFP-APEDTVLLPPNTAPGTPIYTLRALDPDSGVNSRVTFTLLAGGGG-AFTVDPTTGHVRLMRPLGPSGGPAHELELEARDGGSPPRTSHFRLRVVVQDVGTRGLAPRFNSPTYRVDLPSGTTAGTQVLQVQAQAPDG---------------GPITYHLAAEGASSPFGLEPQSGWLWVRAALDREAQELYILKVMAVSGSKAELGQQTGTATVRVSILNQNEHSPRLSEDPTFLAVAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLSEDSKAFRIHPQTGEVTTLQTLDREQQSSYQLLVQVQDGGSPPRSTTGTVHVAVLDLNDNSPTFLQASGAAGGGLPIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLT----GPGSELFSLHPHSGELLTAAPLIRAERPHYVLTLSAHDQGSPPRSASLQLLVQVLPSARLAEPPPDLAERDPAAPVPVVLTVTAAEGLRPGSLLGSVAAPEP------------AGVGALTYTLVGGAD--PEGTFALDAASGRLYLARPLDFEAGPPWRALTVRAEGPGGAG--ARLLRVQVQVQDENEHAPAFARDPLALALPENPEPGAALYTFRASDADGPGPNSDVRYRLLRQEPPVP-------ALR-LDARTGALSAPRGLDRETTPALLLLVEATDRPANASRRRAARVSARVFVTDENDNAPVFASP-------SRVRLPEDQPPGPAALHVVARDPDLGEAARVSYRLASGGD-GHFRLHSSTGALSVVRPL-----DREQRAEHVLTVVASDHGSP-PRSATQVLTVSVADVNDEAPTFQQQEYSVLLRENNPPGTSLLTLRATDPDVGANGQVTYG---GVSSESFSLDPDTGVLTTLRALDREEQEEINLTVYAQDRGSPPQLTHVTVR-----------------------VAVEDENDHAPTFG-SAHLSLEVPEGQDPQTLTMLRASDPDVGANGQLQYRILDGDPSGAFVLDLASGEFGTMRPLDREVEPAFQLRIEARDGGQP-ALSATLLLTVTVLDANDHAPAFPVPAYSVEVPEDVPAGTLLLQLQAHDPDAGANGHVTYYLGAGTAGAFLLEPSSGELRTAAALDREQCPSYTFSVSAVDGAAAGPLSTTVSVTITVRDVNDHAPTFPTSPLRLRLPRPGPSFSTPTLALATLRAEDRDAGANASILYRLAGT---PPPGTTVDSYTGEIRVARSPVALGPRDRVLFIVATDLGRPARSATGVIIVGLQGEAE--RGPRFPRASSEATIRENAPPGTPIVSPRAVHAGGTNGPITYSILSGNEKGTFSIQPSTGAITVRSAEGLDFEVSPR--------------------------------------------------LRLVLQAESGGA---FAFTVLTLTLQDANDNAPRFLRPHYVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSLAASQPARGLFHVDPTTGTITTTAILDREIWAETRLVLMATDRGSPALVGSATLTVMVIDTNDNRPTIPQPWELRVSEDALLGSEIAQVTGNDVDSGPVLWYVLSP-SGPQDP----FSVGRYGGRVSLTGPLDFEQCDRYQLQLLAHDGPHEGRANLTVLVEDVNDNAPAFSQS---LYQVMLLEHTPPGS------AILSVSATDRDS-GANGHISYHLASPADGFSVDPNNGTLFTIVGTVALGHDGSGAVDVVLEARDHGAPGRAARATVHVQLQDQNDHAPSFTLSHYRVAVTEDLPPGSTLLTLEATDADGSRSHAAVDYSIISGNWGRVFQLEPRLAEAGESAGPGPRALGCLVLLEPLDFESLTQYNLTVAAADRGQP------PQSSVVPVTVTVLDVNDNPPVFTR-ASYRVTVPEDTPVGAELLHVEASDADP--GPHGLVRFTVSSGDPSGLFELDESSGTLRLAHALDCETQAR-HQLVVQAAD--PAGAHFALAPVTIEVQDVNDHGPAFPLNLLSTSVAENQPPGTLVTTLHAIDGDAGAFGRLRYSLLEAGPGPEGREAFALNSSTGELRARVPFDYEHTESFRLLVGAADAGNLSASVTVSVLVTGEDEYDPVFLAPAFHFQVPEGARR--GHSLGHVQATDEDGGADGLVLYSLATSSPYFGINQTTGALYLRVDSRAPGSGTATSGGGGRTRREAPRELRLEVIARGPLPGSRSATVPVTVDITHTALGLAPDLNLLLVGAVAASLGVVVVLALAALVLGLVRARSRK---------AEAAPGPMSQAAPLASDSLQKLGREPPSPPPSE--------HLYHQTLPSYGGPGAG---GPYPRGGSLDPSHSSGRGS--AEAAEDDEIRMINEFPRVASVAS----SLAARGPDSGIQQDADGLS---------------DTSCEP-PAPDTWYKGRKAGLL-------------LPGAGATLYREEGPPATATAFLG-GCGLSPAP-------TGDYGFPA---DGKPCVAGALTAIVAGEEELRGSYNWDYLLSWCPQFQPLASVFTEIARLKDEARP----------------------------CPPAPRIDPPPLITAVAHPGAKSVPPKPANTAAARAIFPPASHRSPISHEGS---LSSAAMSPSFSPSLSPLAARSPVVSPFGVAQGPSASALSAESGLEPPDDTELHI-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WDW2-1", "uniprot_id": "X1WDW2_DANRE", "id": "X1WDW2-1", "name": "Protocadherin-16", "aln": "----------------------MKSKGRTIMDPLR------------QIRT----LKWWILVILYVVPQLITIHSSMVPGTLQLQLDEEQPAGTVVGDISAGLPP-DMTASHYFISDHQGTGVSTDLDIDESTGIIKTARVLDREVRDRYSFIAVTMTGITVEVTILVNDINDHAPVFPRKRATFKIPEQTTIGTKFPLEPAVDADEDQLTTQGYIITDGNVGQAFLLETKRGSNKVLYLDLVVNAVLDRETRSSYTLLLEAFDGGSPKRTGQMILDVIVQDINDNAPVFNQSRYHAMISENLQPGNNILQVFASDADEGDNGLVLYDINRRQSDPDHYFVIDSRTGVITLNKPLDYEMRRVHELVVQARDNASQPEVTNSFVTIQVRDYNDNQPTMTIIFLSEDGSPRISEGAQPGQYVARISVTDPDY-GEYANVNVSLEGGNGKFALTTKDSIIYLICVDQILDREEQDHYELRVMATDSGTPPLRAESSFTIQVIDVNDNPPLFDQQEYT-QVIPEVAFPGSFVVQVTARDKDQGPNGDVQYSILQNEGTHSDWFSVDAVTGVVTTLTQLDYEIDPTPSITVVASDRGRPPLSSTAVVKVILQDINDNEPVFGSKFYNASIKENAPARTCFMEVTATDADGGSFGSISYSLGSGQGSVTPSQFTVDKHNGQICTTTSLDRDQGPANYDFTVTAVDGGGLSSVAYVRVDLIDINDNQPAFYPVSYAVSLS-----TQSAPGTSVLKVTAHDPDAAENGRVTYRTVPEGSSPFFTLNKDTGVISLSRA--LHGKANSVITMVVSAQDGGGLTAPVNARVNISIVAGLVAPPVFEQAQYYFVVSEDALRGTQVG-VVRASTKNGVLKDISYIISSGDPTGYFTVDSETGALRTSLPLDHEAQ-PSLNLEVQAHCGNPPAFGQTRVRITVSDVNDNAPVFLPSSSESLILPEDTRMGTVVYKVQAEDRDSGPNGLLSFDLFTSSAHRTFSIDRNSGHLRLIGSLSYETMPRYDLQVIAKDSGAPQLSSTFTLVIHVQAE--NGQGPVFDSLTYRVELKESTPLNTRFLQVRAVNRDGG-----ITTGLSSTSASLAYHLHPDGDAAGFGIVSDSGWLFVKSALDREAKEMYLLTVLATSGN--GQLKKTGSATVRVSVMDENDNTPRFTQERAFLAVRENLPAGTGFGRVSASDRDAGLNGRLSYRLLHLD---RHFQINSHTGEISTKLSLDRELQSSYQLIVVAQDGGTPPRSATGTAFITVLDENDNAPSFSNAQ--TGRELLLQALEGQPSGFLLGTVHAKDPDEGENGTIFYSMS----GPRAERFTLNPNTGELRSSSALSHSERPEYSFIILASDRGSPPQSSIIALKIQVLSSS-----------KGSPNTNSQPLILKSVEGAKPGSMIGSVRSPDSQA---------LPESGQVTFTVVGGTD--FDGTFVVDRQTGDIYLARELDFEKCPRYTLQVEVDDFSMPLPK-SDIITLIIDVQDSNDHSPEFPEDPIIIVVPENTDPGSSFYTFQAVDKDGSGPNSEVHYSILQQWPNIP-------DLLSLDPTTGALSLGMMLDHEKTSSLLLVVQASDSALDVSQRRRGSVTARIFVTDVNDNEPVFISA-------SVVSVMEDQPVGFVVVYVMAVDADQGENGRVTYRIQSGNVRGKFSINPDTGSLSILRPI-----DREEEDLYNLTIVAEDHGLQ-QRSSSQLLSVQVIDVNDEAPYFQESQYEAFIAENQPAGSTVLVVSASDMDQGTNGIVTYG---SIVGDDFSIHPVTGVITTTKALDREAQGVYALTVYARDGGSPPNFAKTTVR-----------------------VTVLDENDNRPAFG-RVYYSLEVPENQEPVTLFTIRATDQDSGDSGLVYYRITDGDHFGDFHLDKKLGVLSTSRALDRESRAKYTLTVEAQDQGIP-SLTSTVTLDISVLDLNDNSPVFPSSSYSVEVSEDASAGSLVLEVSASDKDEGSNSQVVYFLSRESSGMFIVDQHTGRIITAATLDREKVASYNFQVYAMDSSATNPRNSSAEVAVHILDVNDNAPFFITDPLIINVSISSLSNHR---VLATMRAEDKDFGANGSVFYRFAN----PVKGFTINSLTGAIQATEKLQALTQSQRILIVEAMDQGNPSQSSLGVVIVYIREQSY--QGVRFSRNTRDVSLQENAAKGTAVVQIHAQYPDGSTSGINYSIFSGNKQQSFSISHHTGEIWVEDSTGLDFEETPR--------------------------------------------------LRLVVKAETASS---SSFMAVNLLLQDVNDNLPRFQLHNYVAYVREAQGYDHPIIQVLANDLDQGQNGQVTYSIRSSS-MSGLFKIDPITGSISTAAIMDREIWTQTNLVIMATDRGSPRLAGSATLTVIIVDLNDNSPTIPVPREVRVPENTLIGTMITQVTGNDVDSGPALSYTLLLDSDTQGK----FGIHRYGGGVSLTTPLDFEIKTWYTLTVSSSDSKQQSHANLTILVEDVNDNAPVFSQD---LYEVTLAEHSPAGS------SVITVTATDKDS-GENGRITYRVVSTKDMFYIDPSNGTLFIKK-EVEFDSQRP-SILVVIEASDSGTPPLTALSTVQVHVSDVNDNAPVFHQTEYRASVSEDEVPGSTILTLEAADGDLSRDNCGFDFAIASGNIGNTFQIES---SVRFLEGHGFQTVGMLILADKLDFEIASSYNLTIVVSDRGIP------QRSSSVPVLINVMDTNDNPPSFSR-AEYSAVVNEGAERGTEILQLFAIDPDS--TPNGEVQYSISSGDDSELFTVDQWTGAVRLRRSLDSEKQSS-HMFVIQASD--GQG-HFALAPVTVEIKDINNNRPYFPLKSLTASIRENQPQNALVTILHAIDHDKGAYGELRYFLTYN--AGNGKDSFLVNQTSGEVRTRFTFDYEKTNTFNFIAIAMDTGNYTATVTVQVFVTGEDEYDPVFTESDFAFHVPEGAKK--GQSIGQVNANDEDGGVDGIVLYTLANSSPYFELNTSTGVISLKMDAYHR--------HVTRSKRET-RQMTLDVIAHSPLENSRKTSAQITVDVTHTSFGLTTDMNVVLASAITASLAAIVFLIIVVVVIFLLRSQRYK---------EQETCTRIVTHGTVLES------LEDSKVPGGD--------KLYHQTLPGYAADQSGNVGGAYTRGGSLDPSHSSGRGSAEAEAAEDDEIRMINEYPQVASISSSMQEHIAARGPDSGIQQDADQLS---------------DISCEPGMDANQWFKGKKLGSLSGT----------LLASQLPTYRDEG-----GGYLGVGRGLNISH-------PKDYAFPE---DGKPAVDGSLTAIVASDEELRGSYNWDYLLDWCPQFQPLANVFTEIARLKDENAPPNPRRPFHPKAK----------------TDPKPRIDPPPLITSVAHPGAKTVLPKPAVGRTFPHLS--SLRRSPIDHD-----VSSIAMSPSFSPSLSPLAAHSPAIAPFG---GHSSSIISTT----EHEETELRI-----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24292-1", "uniprot_id": "DS_DROME", "id": "Q24292-1", "name": "Protein dachsous", "aln": "MKATLDSVVASETMTRVTFTGNHESKDFAIFHRCRRRSNIKSLYSPPALHPSHMLRSSLLILLAIVLLGSSQAASHDQERERKLEVFEGVAVDYQIGYIGD--FGGIDSGPPYIIVAEAG--VETDLAIDRATGEIRTKVKLDRETRASYSLVAIPLSGRNIRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYH-ANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLT--EFEVRSASGEICIAGELDFERR-SSYEFPVLATDRGGLSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAK-SQVLLNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFE-ASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVN--DNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKT---RVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPIN---SSFQVHPVTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQ-----EDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLN-----------DNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDAD-TGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGVIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELS-ARPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVP----ALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNLVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEARTVLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQS-------LAIIAGNEESAFELLQS---------------KAIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMGGKKASVAVRVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVVGQVTATDSDSGPDGRVVYQLSAPHSHFKVNRSSGAVLIKRKLKLDGDGDGNLYMDGRDISLVISASSGRHNSLSSMAVVEIALDPLAHPGTNLASAGGSSSGSIGDWAIGLLVAFLLVLCAAAGIFLFIHMRSRKPRNAVKPHLATDNAGVGNTNSYVDPSAFDTIPIRGSISGGAAGAASGQFAPPKYDEIPPFGAHAGSSGAATTSELSGSEQSGSSGRGS-AEDDGEDEEIRMINEGPLHHRNGGAGAGSDDGRISDISVQNTQEYLARLGIVDHDPSGAGGGASSMAGSSHPMHLYHDDDATARSDITNLIYAKLNDVTGAGSEIGSSADDAGTTAGSIG-TIGTAITHGHGVMSSYGEVPVPVPVVVGGSNVGGSLSSIVHSEEELTGSYNWDYLLDWGPQYQPLAHVFSEIARLKDDTLSEHSGSGASSSAKSKHSSSHSSAGAGSVVLKPPPSAPPTHIPPPLLTNVAPRAINLPMRLPPHLSLAPAHLPRSPIGHEASGSFSTSSAMSPSFSPSLSPLATRSPSISPLGAGPPTHLPHVSLPRHGHAPQPSQRGNVGTRM", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : ::. :: :: .*:: * ... :* *. . *:* . * * *** **. :* : * **** * * : *:. * .:.* : * * **:**.**: ::.**:*. .: .* ** * * ** * : .....::* *.:: . . :* : . ****. . * * :** ***:* . ::: : *:**: * ******.* :.*. *. :***:***:* . ** * * ******: : * **.:** : :::.**:* :.:***** *:* . :* .:**:::* * *****::.:**** *.**::**.* **: ****** *** ::*:***:*:**:*:***:*:*. ***: * **** . * * * ***.*:***:*. :: ::: *****.* *::: * : *** **: *::* *:* *:* *. : **: :*:.**.:*. :*::** : :* * :* *.: *** * * *** *:*.* * ::*:***** * .***.*: *. *:::*:*:*.* * . :.*::* * * : .*::* : ** :: :.::*.* * * ***.: . ::: : * *** * *** .* .*: :.....*.:: : * *** . *:::*: :. ... :* :: :* : : . * :::.: : :.* ***.* : * * :**: . **:**: :* : * ** ** ** :: * . : : .*** * *:::: :* :: ***:* . : *:::* * **.:. :::.: :.*****:* * :. : :* .: *: :* :* * *** .. ::: *. . *::* :**: * *. : * : * *.* * :: : : : :* . * *:. * *:: .. . .::.:**.* * :: : ... : **: .:***:::::.****::: * *.*:*.... :* * * ::: *:: *:: :. : : ** *: .* * *:* * * *. : * * :. *:::. ***::* .**** :. ::*:* .:* *:* **: .. : * * ***:* : :.. :.. : *.* : ::* * *.*:*.:* *:: . *::.* :* : : * : **. * : : * * *.**:.: * ::** . . . * . *. * ::**: . : :*:*: :. :.:* :* :* : :** ** * . : : . : : : : * * *:::* :..**: : :.* . *: ::.* * * * .*.*.:::* ::: * : * :*. ***** ** * . **:*:* * . :.:.* *:.*: : * **: * * *. : : : : * .. :::* * * *: .:::*.: .*. *:* ::. ** :.:::.: * *: . * : * *** :.:: * : * . :::.* * : * . : ** *.*: :* : *.. . . *. ::* .: .: * :. *::** :*** * *.**.:* . . :: :** ::* * **: * * .*.***..:* .: : *:* * * .. : * * .*: . * :* * :. *.**** .. : * ::* * * * : . : : * * **::* * . *: .* **.. *: ::::.* * * * *.:: * *. : * :: :* : *. **** .** * * * *.. .::. : : : *:**: * * * .:. : .* .::* * * ***..:.* : ::. ** : .:.. : * : * * *.*.:*: *:: : : . ** . . . ::**:. ** ::. * ..* : :*: :**: :*:. :* * *... **:: . :*:*: *.:..: :: : : *:* *** *:* ::** : *.. : ** * * * *...:: * : .. .:. . :* : * ::**** .* ::***.* * :.*:**: * ::* *** **:* : *.* : :*: *:.::.****: *.* * * * : *.: **.* : *. **:* * * : : *. ::.:: **: *:* ***.* * . * . : : .. :::*.*** ** * *.:: * : .. : * :...**.: : . . * : * * * * : : ::*: .* .. . * .**. ::* **.:* * * * :* :** .*:: ::* . ** * *:* :. :. * ** :.* :.::*.*** * * * *.* . : * .: :: * *.* *:. * : ::**: :* :* :*.: : . ** :. : : ::::*.* :* *. :*::* *:: * ***. : **:* .: * ** * * *.:*.*.* : .. . * ::. :* : : . ****: : : * * *. .*:*:* * : ..**: * * : * :* .. * :*:* *.*.*.* ** *:* *: . .:* :* ::*.: :: . * . : ..: . : :: *: : . .. . : *: :. ::.* .. :: ::: : * . : . . . . :: :* :.. .. .. .. .. : * ****** : .**:******* * .. .* .* .:*: : *: * . ::. . : .: . . . :* * : : .* * . * *:*::** .:*** *********.* **:**** **:*******: . * * *. : ..: * . * : ****.*: :* **************::** ::*:* . :* : :: ", "identical_positions": 909, "similar_positions": 1022, "identity": "25.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120410-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q92598-1", "uniprot_id": "HS105_HUMAN", "id": "Q92598-1", "name": "Heat shock protein 105 kDa", "aln": "---------------------------MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNTVSNFKRFHGRAFNDPFIQKEKENLSYDLVPLKNGGVGIKVMYMGEEHLFSVEQITAMLLTKLKETAENSLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIYKQDLPSLDEKPRIVVFVDMGHSAFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEHFCAEFKTKYKLDAKSKIRALLRLYQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQFEELCAELLQKIEVPLYSLLEQTHLKVEDVSAVEIVGGATRIPAVKERIAKFFGKDISTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLIWNHDSEDTEGVHEVFSRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKVKVRVNTHGIFTISTASMVEKVPTEENE-MSSEADMECLNQRPPENPDTDKNVQQDNSEAGTQPQVQTDAQQTSQSPPSPELTSEENKIPDADKANEKKVDQPPEAKKPKIKVVNVELPIEANLVWQLGKDLLNMYIETEGKMIMQDKLEKERNDAKNAVEEYVYEFRDKLCGPYEKFICEQDHQNFLRLLTETEDWLYEEGEDQAKQAYVDKLEELMKIGTPVKVRFQEAEERPKMFEELGQRLQHYAKIAADFRNKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKKSLDQDPVVRAQEIKTKIKELNNTCEPVVTQPKPKIESPKLERTPNGPNIDKKEEDLEDKNNFGAEPPHQNGECYPNEKNSVNMDLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q61699-1", "uniprot_id": "HS105_MOUSE", "id": "Q61699-1", "name": "Heat shock protein 105 kDa", "aln": "---------------------------MSVVGLDVGSQSCYIAVARAGGIETIANEFSDRCTPSVISFGSKNRTIGVAAKNQQITHANNTVSSFKRFHGRAFNDPFIQKEKENLSYDLVPMKNGGVGIKVMYMDEEHFFSVEQITAMLLTKLKETAENNLKKPVTDCVISVPSFFTDAERRSVLDAAQIVGLNCLRLMNDMTAVALNYGIYKQDLPNAEEKPRVVVFVDMGHSSFQVSACAFNKGKLKVLGTAFDPFLGGKNFDEKLVEHFCAEFKTKYKLDAKSKIRALLRLHQECEKLKKLMSSNSTDLPLNIECFMNDKDVSGKMNRSQFEELCAELLQKIEVPLHSLMAQTQLKAEDVSAIEIVGGATRIPAVKERIAKFFGKDVSTTLNADEAVARGCALQCAILSPAFKVREFSVTDAVPFPISLVWNHDSEETEGVHEVFSRNHAAPFSKVLTFLRRGPFELEAFYSDPQGVPYPEAKIGRFVVQNVSAQKDGEKSRVKVKVRVNTHGIFTISTASMVEKVPTEEEDGSSLEADMECPNQRPTESSDVDKNIQQDNSEAGTQPQVQTDGQQTSQSPPSPELTSEESKTPDADKANEKKVDQPPEAKKPKIKVVNVELPVEANLVWQLGRDLLNMYIETEGKMIMQDKLEKERNDAKNAVEECVYEFRDKLCGPYEKFICEQEHEKFLRLLTETEDWLYEEGEDQAKQAYIDKLEELMKMGTPVKVRFQEAEERPKVLEELGQRLQHYAKIAADFRGKDEKYNHIDESEMKKVEKSVNEVMEWMNNVMNAQAKRSLDQDPVVRTHEIRAKVKELNNVCEPVVTQPKPKIESPKLERTPNGPNIDKKE-DLEGKNNLGAEAPHQNGECHPNEKGSVNMDLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB40EBT1-1", "uniprot_id": "A0AB40EBT1_DANRE", "id": "A0AB40EBT1-1", "name": "Heat shock protein 105 kDa", "aln": "MTDAYTHGFVCPSDLSTLLAVPSRVRDMAVVGFDVGFQNCCIAVVKSGGIETVSNEFTDRCTPSVISFGSKNRAIGNAAKNQMITNPSSTVFHFKRLHSRLYHDKVVQAEKANLPYDLVPLNDGKVGVQVMYLDQEHHFSIEQISAMLLTKLKDIAEANLQKKVLECVISIPSFFTDSERRSVLDAAKIAGLNCLKLMNDSTAVALNYGIYKEDLPGSDENPKIVAFVDLGHSAFQVSICAFNRGKVKVLSTAFDPYLGGKDFDQRLVDHFCAEFKSKYMMDVKSKTRALLRLTQECEKLKKLMSSNSTELSLNIECFIDDKDVCGRMNRAKFEEMCADLIERVKFTLMKAVEQAGVRLQDISAVEIVGGATRIPAVKAQISSFFRRDVSTTLNADEAVARGCALQCAMLSPAFRVREFSITDVIPFPISLSWSSEADEGKSCHEIFSRNHPCPSAKMITFYRNKPFILEAFYSDKSSLPFPEAKIGEYKVQNIQPQENREKAKVKVKVEVNRSGVVSVSSAAVVLRVRSDESEITEINEDVDS------HDASDDTDVQDKTEEVNIELSVNKENLPTAQCPP----MEKEQNQRETLSMNGEVNSHPPHAKKAKMKVKHVVLPMEETFNQQLPKDRLSAYTEQENKMIQQDRQEKERNNAKNAVEENVYYFRHKLEGSYQTFLNAQEHQAFSELLNGTENWLYDEGADQDKQTYINRLAEIHKLGLPVENRYRESIRRPRMFEELSAKIQSYMTIVEDYKNGSESYCHIDAMDMDKVRVCVKDTQVWMTNIQDSQDKLTPDQEPAIHSTQIQKKLQTLNNVCGEIVSKPKPRVDSP-MDDTIQPERLHKHK--------SPEDVTMDYTDFVQNERKNNHVNI-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *:***:*** *.* ***.::*****::***:***************:** ***** **:...** ***:*.* ::* .:* ** **.*****:::* **::***:.:** **:***:********: ** .*:* * :****:******:*********:*.*****:**** ***********:***. :*:*::*.***:***:**** ****:**:***.*****:****:**::**:*******:** :*.*** ****** ***************:*.******::****.*:***::***:**:*:::::..* . : *: :: :*:**:************* :*:.** :*:*******************:*****:*****:**.:****** *. :::: :. **:*****..* :*::** *. ** ******* ..:*:******.: ***:..*:: **::*****.** *:.::*:*::* :* ::*.: . : *::. .... *.::*:...*.. : .*:.: *:*.** .:*.: :: . * : .:**.***.*:** :* **:* .: ** :* *. * * *.*** **: *****:******* ** **.** *.*:.*: *:*: * .**. **:***:** ** **:*:::* *: *:* **: *::*: .**:::***. ::* * .*. *::. .*.* *** :*.**. .*::. **.*: ::* * : **:*.::: :*: *:: ***.* :*::***:::** :: * : .:.*:: : . : : **: . :::: ", "identical_positions": 451, "similar_positions": 263, "identity": "50.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120411-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1Z7A6-1", "uniprot_id": "ASAP_DROME", "id": "A1Z7A6-1", "name": "ArfGAP with SH3 domain, ANK repeat and PH domain-containing protein", "aln": "MPPSLIAVSEFVEETRSDYSSPTTSTFASRMPDCRHTIGVLEERLEFDREGLTKLKKAVKAIHNSGNTHVDNEMFMVRALERLGGKVIEQDEPDIGAAFLKFSVVTKELSALMKTLMQNINNIVMFPVDSMLKSELRGVKGDMKRPFDKAAKDYEAKFIKIEKEKKAQAKEAGMVRTEIDAAVVAEEMEKERRLYQLQTCEYLLKYKDIKTKTGIELLQHLIEYYHALSNYFKDGLQTIEHFGTYIGDLSEKLHEIKQKQDEDRRSLLDLRTVLRSTPDFERVDNVPSSESRSGGAGYSLHQLQGDKHHGVTRQGHLLKKSEGKVRRVWQKRRCRVTSDGFLDIFHADESKPPTRVNLLTCQIKPVPDDKRGFDLISYNRPYHFQAEDEGDQKAWMAVLVNCKEKALTKAFQHANPQMSPSLVELQKTVIRYVQLLPGNDRCCDCGSRNDVTWISLNFGILVCIQCSGVHRDLGVHHSRIQSLTLDNLTTANLL--IARAMGNSTLNDIMEAKLG---RGKLQHESSMEERYDFIRAKYVAKRYVMRTCSDDNDLRCDLEQAVVNADMSQLLQVWAEGADLTCCLPS--SDAGETALHLAVLREMGSTLHIVDFLIQNMPPKGLNKATNPAGLLDVTGKNTALHLCALHDRRECMKLLLRSGADYELKNSQNKTALDIAKEMGHNSCRELIECAIKREKSAFDHINTDWNLPNEDGSTDFSDDETVIDERKSRSRPPSFAGGDSPVLRSRSSTCDSIQSSSSPIANCPSRQFTLPSGLPSYTHSAGTSPKQHISVGQYLGSATNVGGNGPGNGGSSPSSASSQSVRAARNSLNMQSDLGGHVTGARKSTSTANMNSLKKRTAPAPPPGTLGSASSSSFYGTLPHPPRHSQNFDASDIRAINHKNQSLDVAYGTLPHLRSVESSPRGGGGYGYGVSQDPGGSGNGSNNSLMPAMTTFGHKRSPSGESLNRNIHLAGAKLVLPPTGELPTLKHVDKSALTRPKIPPPGPPSEREISNGQSNESISSMDEGPVAPPRKLVNQSANFPDYESWHTDMDSSGGGLDHSAESNVSSSDNDRLNSSPDNPSKTGGAGLGGKFHYNGQRRCRALYDCVADNDDELEFKEGEILIVLNERTDDENWMEGIIEGQPTRKGMFPVSFVHMLPD", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M2BGM9-1", "uniprot_id": "A0A8M2BGM9_DANRE", "id": "A0A8M2BGM9-1", "name": "Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3", "aln": "-MPEFISVDEFIAETLEDYSSPTTSSFYTKMTSCRNSANNIEEALDSDRTILQKMKKAAKAKHISGQDHISHLESYINSMEKLAVNFRNNGEQEVASAFNKFAEFSKELLTPMKNLLKSMLHNVNFFLDSLVKGDLKEVKGDLKKPFDKAWRDYENKFTKIEKEKRELAKQYGMVRTEVSGGEIAEEMEKERRMFQLQMCEYLIKVNEIKTKKGVDLLQNLIKHYHSQCNFFQECLAATEKLKQYIDALTGQLSAIKHKQDEEKRQLCSLRDQLR-PALLPEFKEQSRRDSLSRQTVYSMHQLQGNKQYGTEKSGYLYKRSDG-LRKMWQKRKCTVQN-CYLTIAHGTPNKSPAKLNLLTCQVKPSLEDKKCFDLISHNRTYHFLADDECDCVAWISVLTNSKQEALNVALDERRPSGENSVEDLTRAITEDIRRMPGNSVCCDCGAS-DPSWISINLGILTCIECSGIHREMGVHYSRIQSLSLDKLGTSELL--LARNVGNLGFNEIAEANLPSV-SVKPSAESDMAVRKDFILSKYMEWQFAQRSGGSLETKRKYLQDAVRSRDVFSLLQLYTERTDFSLSLPCPLQEKGETALHLAVLLADRTSLHVADFLFHNCN--NLDVQTMKG--------NTALHYCCQHNKTECLKLLLRAKANTHIKNDNGETGLDVARRLKHSLCEELIHQSQNDQFNMHVHVEYDWRLRQDD----LYESDDDLEDKTG------------PVKKERLGRPFSLYHSSS------------------SSHAGGGS-----------------GGGGLFNVGRRLALARGDNRREVYASPNSQTRSLDSPPPPPPSSPAPPLPPRVRAPNVPPPPPPMSSPD-----GWTSHEVKSSKKRTPPPPLIIRHKRTYSEPSPQVPPSPHSTRQGP-----ADYGVPTGP---------------RSFGGPDSPFQKCVSGSPKYP--------TSTLNSLSELPERAGFR--------------ADGESG-------------SSHFLYQTPQPMGSAGHHTPGLSPTSPRSFSLEANGGSSSSSCHSAPHPLPRKN--------LMKPKLRRVKAMYDCVADHHDELTFNEGDVLVVLGE--DDADWWHGYIEGQPDRMGLFPASFVSMLAE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q04412-1", "uniprot_id": "AGE1_YEAST", "id": "Q04412-1", "name": "ADP-ribosylation factor GTPase-activating protein effector protein 1", "aln": "------------------------------------------------------------------------MDFYTTDINKNVVPLFSKGTVARTASKAQYPSWCNNALKLTNILLKSLR-------------------------------------CKFQTNRCEDDRGFEVYCVILKS--IALLMAAKESLILLQIPPSLPSGFPFRSPQ-------------LSFTYLSTRLSGSQHKSTHSHHINHQTHPIHSSSSNSN------------------------------------------------SNNRIPTKT------------------------------------------------------------------------------DSSKQHTQHFSFANAGASNRDELLSIVRKIDK------SNLKCCDCGSTATVEWVSINLLCILCIKCSGVHRSLGSHISKIRSLTLDNFTSLELMHLLQNNVSNSNVNAIYESNLRNFPVKKITANSDDSERSKFIIDKYQFKKFVIDSNQGREASLKSLIKAIHLDSVFMMQRAIAQ-----------------SKYSLRELTAS---------------------------------------------EKEQNDLNHSSIFQYSLKHYEIVDGTPIFFITEFLLCNGIHIDN-------LPKITTNWS----------------------------------PKVLEYWETKLEMYGTFQ---------------------------------------------------------AVNTSRPRSGPHLNMHSNVDSASSYNKKHDLRVNIPERSASASKR---------------WSLSSIPKSSQNLMSPTNLLTMHKSLKLAKKDKK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::: . .:. :: ::. :: : *::.: *::.:: : : . :.. :* * :. : ** * . ::: .::. * :: : :. : *: ...:.. .. : .:: ..*:.: :: . .. .: .: : : . .* *****: *:*:*: : **:***:**.:* * *:*:**:**:: : :*: : . :.* .* * *::* * :*. * .** ** ::. : . : * .*: .: : : :: : * * . * .* : : :*: : . : . *. : :: :* * . .: : . * . . * :: . . : . . : *:: .. ** ", "identical_positions": 62, "similar_positions": 155, "identity": "5.34%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120411-11", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96HP0-1", "uniprot_id": "DOCK6_HUMAN", "id": "Q96HP0-1", "name": "Dedicator of cytokinesis protein 6", "aln": "--MAASERRAFAHKINRTVAAEVRKQVSRERSGSPHSSRRCSSSLGVPLTEVVEPLDFEDVLLSRPPDAEPGPLRDLVEFPADDLELLLQPRECRTTEPGIPKDEKLDAQVRAAVEMYIEDWVIVHRRYQYLSAAYSPVTTDTQRERQKGLPRQVFEQDASGDERSGPEDSNDSRRGSGSPEDTPRSSGASSIFDLRNLAADSLLPSLLERAAPEDVDRRNETLRRQHRPPALLTLYPAPDEDEAVERCSRPEPPREHFGQRILVKCLSLKFEIEIEPIFGILALYDVREKKKISENFYFDLNSDSMKGLLRAHGTHPAISTLARSAIFSVTYPSPDIFLVIKLEKVLQQGDISECCEPYMVLKEVDTAKNKEKLEKLRLAAEQFCTRLGRYRMPFAWTAVHLANIVSSAGQLDR-DSDSEGERRPAWTDRRRRGPQDRASSGDDACSFSGFRPATLTVTNFFKQEAERLSDEDLFKFLADMRRPSSLLRRLRPVTAQLKIDISPAPENPHFCLSPELLHIKPYPDPRGRPTKEILEFPAREVYAPHTSYRNLLYVYPHSLNFSSRQGSVRNLAVRVQYMTGEDPSQALPVIFGKSSCSEFTREAFTPVVYHNKSPEFYEEFKLHLPACVTENHHLLFTFYHVSCQPRPGTALETPVGFTWIPLLQHGRLRTGPFCLPVSVDQPPPSYSVLTPDVALPGMRWVDGHKGVFSVELTAVSSVHPQDPYLDKFFTLVHVLEEGAFPFRLKDTVLSEGNVEQELRASLAALRLASPEPLVAFSHHVLDKLVRLVIRPPIISGQIVNLGRGAFEAMAHVVSLVHRSLEAAQDARGHCPQLAAYVHYAFRLPGTEPSLP----DGAPPVTVQAATLARGSGRPASLYLARSKSISSSNPDLAVAPGSVDDEVSRILASK---------------------------------------------------------------LLHEELALQWVVSSSAVREAILQHAWFFFQLMVKSMALHLLLGQRLDTPRKLRFPGRFLDDITALVGSVGLEVITRVHKDVELAEHLNASLAFFLSDLLSLVDRGFVFSLVRAHYKQVATRLQSSPNPAALLTLRMEFTRILCSHEHYVTLNLPCCPLSPPASPSPSVSSTTSQSSTFSSQAPDPKVTSMFELSGPFRQQHFLAGLLLTELALALEPEAEGAFLLHKKAISAVHSLLCGHDTDPRYAEATVKARVAELYLPLLSIARDTLPRLHDFAEGPGQRSRLASMLDSDTEGEGDIAGTINPSVAMAIAGGPLAPGSRASISQGPPTASRAGCALSAESSRTLLACVLWVLKNTEPALLQRWATDLTLPQLGRLLDLLYLCLAAFEYKGKKAFERINSLTFKKSLDMKARLEEAILGTIGARQEMVRRSRERSPFGNPENVRWRKSVTHWKQTSDRVDKTKDEMEHEALVEGNLATEASLVVLDTLEIIVQTVMLSEARESVLGAVLKVVLYSLGSAQSALFLQHGLATQRALVSKFPELLFEEDTELCADLCLRLLRHCGSRISTIRTHASASLYLLMRQNFEIGHNFARVKMQVTMSLSSLVGTTQNFSEEHLRRSLKTILTYAEEDMGLRDSTFAEQVQDLMFNLHMILTDTVKMKEHQEDPEMLIDLMYRIARGYQGSPDLRLTWLQNMAGKHAELGNHAEAAQCMVHAAALVAEYLALLEDHRHLPVGCVSFQNISSNVLEESAISDDILSPDEEGFCSGKHFTELGLVGLLEQAAGYFTMGGLYEAVNEVYKNLIPILEAHRDYKKLAAVHGKLQEAFTKIMHQSSGWERVFGTYFRVGFYGAHFGDLDEQEFVYKEPSITKLAEISHRLEEFYTERFGDDVVEIIKDSNPVDKSKLDSQKAYIQITYVEPYFDTYELKDRVTYFDRNYGLRTFLFCTPFTPDGRAHGELPEQHKRKTLLSTDHAFPYIKTRIRVCHREETVLTPVEVAIEDMQKKTRELAFATEQDPPDAKMLQMVLQGSVGPTVNQGPLEVAQVFLAEIPEDPKLFRHHNKLRLCFKDFCKKCEDALRKNKALIGPDQKEYHRELERNYCRLREALQPLLTQRLPQLMA----PTPPGLRNSLNRASFRKADL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VDR9-1", "uniprot_id": "DOCK6_MOUSE", "id": "Q8VDR9-1", "name": "Dedicator of cytokinesis protein 6", "aln": "--MAASERRAFAHKINRTVAAEVRKQVSRERSGSPHSSRRSSSSLGVPLTEVIEPLDFEDVLLSRPPEVEPGPLRDLIEFPVDDLELLKQPRECRTTESGVPEDGQLDAQVRAAVEMYSEDWVIVRRRYQHLSTAYSPITTETQREWQKGLTCQVFEQDTPGDERTGPEDVDDPQHCSGSPEDTPRSSGASGIFSLRNLAADSLLPTLLEQAAPEDVDRRNEALRRQHRAPTLLTLYPAPDEDEAVERCSRPEPPREHFGQRILVKCLSLKFEIEIEPIFGTLALYDVREKKKISENFYFDLNSDSVKGLLRAHGTHPAISTLARSAIFSVTYPSPDIFLVVKLEKVLQQGDISECCEPYMVMKEADTAKNKEKLEKLRLAAEQFCTRLGRYRMPFAWTAVHLANIVSRP--QDR-DSDSEGERRPTWAERRRRGPQDRGYSGDDACSFSSFRPATLTVTNFFKQEAERLSDEDLFKFLADMRRPSSLLRRLRPVTAQLKLDISPAPENLHFCLSPDLLHVKPYPDPRGRPTKEILEFPAREVYAPHSCYRNLLFVYPHSLNFSSRQGSVRNLAVRIQYMAGEDQSQALPVIFGKSSCSEFTREAFTPVVYHNKSPEFYEEFKLRLPACVTENHHLFFTFYHVSCQPRPGTALETPVGFTWIPLLQHGRLRTGPFCLPVSVDQPPPSYSVLTPDVALPGMRWVDGHKGVFSVELTAVSSVHPQDPHLDKFFTLVHVLEEGIFPFRLKETVLSEGTMEQELRASLAALRLASPEPLVAFSHLVLDKLVRLVVRPPIICGQMVNLGRGAFEAMAHVASLVHRNLEAVQDSRGHCPLLASYVHYAFRLPGGDLSLP----GEAPPATVQAATLARGSGRPASLYLARSKSISSSNPDLAVVPGSVDDEVSRILASKGVDRSHSWVNSAYAPGGSKAVLRRVP----------------------------PYCGADPRQLLHEELALQWVVSGSAVRELVLQHAWFFFQLMVKSMELHLLLGQRLDTPRKLRFPGRFLDDIAALVASVGLEVITRVHKDMKLAERLNASLAFFLSDLLSIADRGYIFSLVRAHYKQVATRLQSAPNPTALLTLRMDFTRILCSHEHYVTLNLPCCPLSPPASPSPSVSSTTSQSSTFSSQAPDPKVTSMFELSGPFRQQHFLSGLLLTELALALDPEAEGASLLHKKAISAVHSLLCSHDVDSRYAEATVKAKVAELYLPLLSLARDTLPQLHGFAEGSGQRSRLASMLDSDTEGEGDIGSTINPSVAMAIAGGPLAPGSRTSISQGPSTAARSGCPLSAESSRTLLVCVLWVLKNAEPTLLQRWAADLALPQLGRLLDLLYLCLAAFEYKGKKAFERINSLTFKKSLDMKARLEEAILGTIGARQEMVRRSRERSPFGNQENVRWRKSATHWRQTSDRVDKTKDEMEHEALVDGNLATEASLVVLDTLETIVQTVMLSEARESILSAVLKVVLYSLGSAQSALFLQHGLATQRALVSKFPELLFEEDTELCADLCLRLLRHCGSRISTIRMHASASLYLLMRQNFEIGHNFARVKMLVTMSLSSLVGTTQNFSEEHLRKSLKTILTYAEEDIGLRDSTFAEQVQDLMFNLHMILTDTVKMKEHQEDPEMLMDLMYRIARGYQGSPDLRLTWLQNMAGKHAELGNHAEAAQCMVHAAALVAEYLALLEDSRHLPVGCVSFQNVSSNVLEESAISDDILSPDEEGFCSGKNFTELGLVGLLEQAAGYFTMGGLYEAVNEVYKNLIPILEAHRDYKKLAAVHGKLQEAFTKIMHQSSGWERVFGTYFRVGFYGTRFGDLDEQEFVYKEPSITKLAEISHRLEEFYTERFGDDVVEIIKDSNPVDKSKLDPQKAYIQITYVEPHFDTYELKDRVTYFDRNYGLRAFLFCTPFTPDGRAHGELAEQHKRKTLLSTEHAFPYIKTRIRVCHREETVLTPVEVAIEDMQKKTRELAFATEQDPPDAKMLQMVLQGSVGPTVNQGPLEVAQVFLSEIPEDPKLFRHHNKLRLCFKDFCKKCEDALRKNKALIGPDQKEYHRELERHYSRLREALQPLLTQRLPQLLA----PSSTSLRSSMNRSSFRKADL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32TJM6-1", "uniprot_id": "A0AB32TJM6_DANRE", "id": "A0AB32TJM6-1", "name": "", "aln": "MATLTSERRAFAHKINRTVASEVRKQVSREYGSPQMSKKRAGAHQPVPLTEVVEPVDYEEYVSSHPPGAEPGPLRQLLEFPRDDLELVLQERECVTIEPPVPEEDSLDPRVRDALGVYTDDWLIIQRKYQCYSTLQTPHNSERQREKQKGLVKQTFELDEAAIERQ--DEQDDPKRHSVSLDDTPRGSWASSIFDLKNSIPDALLPSVLERTAAEEMDRRNADNRQQGRHNHLLGLYPAPDEDEAVERCAIPEVPKEHSGQRIMVKCLSLKFEIEIEPIFGSLALYDVREKKKISEDFHFDLNSDQMKGLLRPHNPHVAISTLARSAIFSITYPSPEIFLVIKLEKVLQQGDIGECCEPYMVMKESDSIKHKEKLEKLRAQAEQMCSRLGGFRMPFAWTAIHLLNIVSSVGGLDRSDSDSDTERKGTWNERKKKG-FERMSVGEDMCNFTNFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPVTAQLKIDISPAPEAPHYCLSPELLHVKPYPDPRVRPTKEVLEFPARYVYTPHTTYRNLLYVYPQSVNFSSRQGSVRNIAVKVQFMAGEDPSQAMPVIFGKSSCAEFYKEAYTPVIYHNKSPEFYEEVKMKIPANLTDNHHLLFTFYHISCQPKQNTLLETPVGYTWIPLMQHGRLRSGSFSLPVSVEKPPPSYSVLTPDVQLPGMKWVDNHKGVFNVEVKAASSVHTQDPHLDKFFTLVYVLEEYSFPFRLKDVIITESNVEAELKASMAALKGALLDTCVRFLHQLMSKLILLIVHPPVIAGQIVNLGRAAFEAMALLVNQIHKNLEGNQDHHGRNNLLSSYIHYCFHLPTTEPVSPPAVGAAAYDLPIHYATLSRATSRPSALLLSRSKSISNSNPDLASTPATPDEEVQRIIGSKGIDRSHSWVNSAYAPGGSRAVLRRNPNSSCELKQASERACNRMSAYIETTSLLCPPSRQIAKKLLHEELALQWVVSTSTVREASLQQAWFFFQLMVKSMSHHLFLSSRLDMPRRQRFPDRFVDDIAALVCAISADIASRYHKDVELVERLNSSLAFFLNDLLSLMDRGFVFNLVRSYYKQINNKLHTAQNPSSLTALRMDFIRIICSHEHYVILNLPCATLSPPASPSPSTSSTTSQSSAFSSHAQDQGVVSMFELSVPFRQQHFLSGLLLAELSLILEPDGESVFFLHKKAISALHSLLCSHDADPRYTDPQVRSHVAQLYLPLIPIIMETLPKLHDFTDTSPQRVRHASALADDNDPDN---GTISQSVAMAIAGSPLP-HSKANPFTLPSVAGRQCGVLSAECSRTLLVCFLWVWKNADAGLLERWVSDLSVPQINRLLDLLHLCLSCFEYKGKKALERINSLTFKKSQDMKARLEEAILGTIGARQEMVRRCRERSPYGGQENVRWRKNVTHWRQNADRVDKTKAEVEQESVVDGNLATEAALIALDTLEIIVKTVVMSELKESVLGGVLRVLLHSMAGNQSALFLQHCFSTQRALVYKFPEMLFEEDTELCADLCLRLLRHCSSSVSSVRSHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQTFNEEHLRRSLKTILTYAEDDLELRDSPFPEQVQDLVFNLHMILTDTVKMKEHQQDPEMLIDLMYRIAKGYQNSPDLRLTWLQNMAGKHSEKGNHAEAAHCLVHSAALVAEYLNMLEDCRYLPIGCVSFQSISSNVLEESAVSDDILSPEEEGICSGKYFSESGLVGLLEQAAASFNMAAMYEAINEVYKILCPIHEANRDFKKLASVHGKLQDAFNKVYNQSSGWERMFGTYFRVGFYGCRFGDLDEQEFVYKEPSITKLAEISHRLEEFYSERFGDEVVAIIKDSNPVDKNKLDPNKAYLQITYVEPFFDTYELKERITYFDKNYNLRTFMYCTPFTLDGRAHGDLHEQYKRKTILTTSHAFPYIKTRINVIHKEEIILMPMEVAIEDMQKKTQELAFATHQDPADPKMLQMVLQGCVGTTVNQGPLEVAQVFLSEIPEDPKLFRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYHRELERNYLKLKEALFPLINRKIPQLYRPLPLPTLPTQRNSLSRSSFRRLEC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :***************:********* ... *.:*..: ******:**:*:*: : *:** .******:*:*** *****: * *** * *. :*:: .**.:** *: :* :**:*::*:** *: :* .:: *** **** *.** * .. ** :: :*.:: * * :****.* **.**.*:* .*:***::**::*.*::**** *:* * ** **************: ** *:** ****:***************** **************:*:******.:*****.*..* ************:*****:****:***********.********:** *: *:******** ***:*:*** :********:** **** ** ****: **: :* :*:::* :* *:* *.*:.***************.:*******:***********:************:******* *:****:***:******* *****:****** **:**: *****:***:*:***********:**::*:*:*** ***:*********:** :**:***:***********.*:::** :*:****:*****:****: .* ******:*****:******:*.*.*****::************ ****:***.*****.**:.*.****.***:********:**** ******:.:::*..:* **:**:***: * :. * * * ::.**: *:::**:*.**:*****.****** :.. :*:.**. ** :*: *::*:**.*:** : * * .:: ***:*.:.**::* *:******.****** .*.: *:**.**:.** ************* *:*** **:************ **:*..*** **: ***.**:***:*** ::. :: :* ***::*.*:**:******.****: ***::*.***::***: .:*::: **::* :***:* **:******* *****..**********.********:***:* * *.****** ********:****:**:* *:*:.*.. :********:*****.**.*.**::. *:::**:*****:.: :***:**.*:: . ** * ** * .*.: :. .**. ********.**. *::. *..*.* ****.*****.*.*** **::. **:**.:**::**:.******:***:.********:*********** ***********************.*****:*. *******..***:*.:******* *:*:*::*:*******:*:.***** **:**::** :**:*..**:*:*:*:.. ******** ::****** ****:********************.* :*::* *****************:******* ***********:*.*.*****:**********:*: ****.*.******:*****************:*****:*******:***.****************:* *******:*:**:******** :*** *:**:******.:*********:*******:***:**** *:* **********. *.*..:***:***** * ** **:**:****:******:**.*: :*******:*********** :******************************:*****:** **********.***.:***:*******.*******:*:****:**.**:*::***** ******:* **:****:*:*.**********.* *:** :* *:***********:******.***.*.*********.**.**************:********************** *:*********:***************:* :*:*** **:.:::*** *: . *.*:.*:***: : ", "identical_positions": 1406, "similar_positions": 434, "identity": "66.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120411-14", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99569-1", "uniprot_id": "PKP4_HUMAN", "id": "Q99569-1", "name": "Plakophilin-4", "aln": "MPAPEQASLVEEGQPQTRQEAASTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNTGVSKPRVSDAVQPNNYLIRTEPEQGTLYSPE--QTSLHESEGSLGNSRSSTQMNSYSDSGYQEAG-SFHNSQNVSKADNRQQHSFIG-STNNHVVRNSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVISTGVSPSRGSLRTSLGSGFGSPSVTDPRPLNPSAYSSTTLPAARAASPYSQRPASPTAIRRIGSVTSRQTSNPNGPTPQYQTTARVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHDMEQFGQQQYDIYERMVPPRPDSLT------GLRSSYASQHSQLGQDLRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTVELQGSQTALYRTGSVGIGNLQRTSSQRSTLTYQRNNYALNTTATYAEPYRPIQYRVQECNYNRLQHAVPADDGTTRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVCRLGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSVLSDETMAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTNQQMSPIIQSVGSTSSSPALLGIRDPRSEYDRTQPPMQYYNSQGDATHKG-LYPGSSKPSPIYISSYSSPAREQNRRLQHQQLYYSQDDSNRKNFDAYRLYLQSPHSYEDPYFDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKR-PSYRAEQYPGSPDSWV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q68FH0-1", "uniprot_id": "PKP4_MOUSE", "id": "Q68FH0-1", "name": "Plakophilin-4", "aln": "MPAPEQGSLVEEGQPQTHQEAVSTGPGMEPETTATTILASVKEQELQFQRLTRELEVERQIVASQLERCRLGAESPSIASTSSTEKSFPWRSTDVPNPGVSKPRVSDTIHPNNYLIRTEPEQGTLYSPE--QTSLHESEGSLGNSRSSTQMNSYSDSGYQEAG-SFHNSQTVNKADSRQ-HPFTG-STSNHVVRTSRAEGQTLVQPSVANRAMRRVSSVPSRAQSPSYVTSTGVSPSRGSLRTSLGSGFGSPSVTDSRPLNPSAYSSSTLPAQRAASPYSQRPASPTAVRRVGSVTSRQTSNPNGPVPQYQTTTRVGSPLTLTDAQTRVASPSQGQVGSSSPKRSGMTAVPQHLGPSLQRTVHDMDQFGQQQYDIYERMVPPRPDSLT------GLRSSYASQHSQLGQELRSAVSPDLHITPIYEGRTYYSPVYRSPNHGTVELQGSQTALYRTGSVGIGNLQRTSSQRSTLTYQRNNYALNTAATYAEPYRPVQYRVQECSYNRLQHTGPADDGATRSPSIDSIQKDPREFAWRDPELPEVIHMLQHQFPSVQANAAAYLQHLCFGDNKVKMEVYRLGGIKHLVDLLDHRVLEVQKNACGALRNLVFGKSTDENKIAMKNVGGIPALLRLLRKSIDAEVRELVTGVLWNLSSCDAVKMTIIRDALSTLTNTVIVPHSGWNNSSFDDDHKIKFQTSLVLRNTTGCLRNLSSAGEEARKQMRSCEGLVDSLLYVIHTCVNTSDYDSKTVENCVCTLRNLSYRLELEVPQARLLGLNELDDLLGKESPSKDSEPSCWGKKKKKKKRTPQEDQWDGVGPIPGLSKSPKGVEMLWHPSVVKPYLTLLAESSNPATLEGSAGSLQNLSAGNWKFAAYIRAAVRKEKGLPILVELLRMDNDRVVSSVATALRNMALDVRNKELIGKYAMRDLVNRLPGGNGPSILSDETVAAICCALHEVTSKNMENAKALADSGGIEKLVNITKGRGDRSSLKVVKAAAQVLNTLWQYRDLRSIYKKDGWNQNHFITPVSTLERDRFKSHPSLSTTNQQMSPIIQSVGSTSSSPALLGIREPRSEYDRTQPPMQYYNSQGDTTHKG-LYPGSSKPSPIYISSYSSPAREQNRRLQHQQLYY-QDDSTRKTLDAYRLYLQSPRSYEDPYCDDRVHFPASTDYSTQYGLKSTTNYVDFYSTKR-PSYRAEQYPGSPDSWV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32TXB9-1", "uniprot_id": "A0AB32TXB9_DANRE", "id": "A0AB32TXB9-1", "name": "", "aln": "MPTPRQSPVEEREVLSGEGRSNNNNMATDTTTTTTNLLASVKEQELQFERLTRELEEERQIVANQLERCRLGAESPGAASDSSSEKSLLWRSAESSGAGVSKP--SDGCPSPTFGVRG---QGSLYSPELEQISLRESEGSAANSRSSTQMNSYSDSGYQEVSGYYSNTVTPRRSEGRSQSTSSAPSGSPTLAMSSRAEGQASAQVGSSGRVMRRVSSVPSRAPSPLYTPSP--PASRQPLRTSLGSPYGSPIVSEPRPL-PSIFPGTTLPP---ASSHAPDPLHSSYLGRHGNGTGSESGSP-----------------TLLRAGMTAQPQQYGTLGKHDTRAYESTHS----------------SFGSRAYDIFERMVLSRPDSLTVSYLHLGLQTSYS-QNSQLGQDTR---SPDCHVTPIYEDRTFQNPLYQSPTHG------SQSAASRN-NTGFGTLQRTTSQCSTLRYQRGLFSMGSMATHSDTYRPGHYRQADSNYS--RHSAALDNAVTRSPSIDSVHKDPREFAWRDPELPEVIRMLQHHFPSVQANAAAYIQHLCYGDNRIKAEVCRLGGIRHLVDLLDHKTLEVQRNACGALRNLVYGKATDDNKVCVRNSGGIPALVRLLRKTPDSEVRELVTGVLWNLSSCDSVKMTITRDALGPLTNTVIIPHSGWGAAPQREDQKLKLHSSLVLRNTTGCLRNLSSAGEEARRQMRCCEGLIDSLLYIIKTCVNTSDYDSKIVENCVCTLRNLSYRLELEMPPSRLMGTQDLDTLLGPDTSSKQADYSCWGLRKKKKKRSWQDQQWDGVGPIPGFSGSPKGAEMLWHPSVVKPYLTLLAESSNPATLEGAAGSLQNLSAGTWRFASYIRAAVRKEKGLPILVELLRMDNDRVVCSVATALRNMALDARNKELIGKYAMRDLVTRLPG-NGPSLLSDETVAAVCCALHEVTSRNMENARALAQTGGIDKLVTISRGRGERYSMKVVKAAAQVLNTLWQYRDLRTFYKKDGWNQNHFITPVSTLERDRYRSQPTLPTSNVQMSPVIQSGGSATSSPAMLGIRGQRLNQRRTQSSMQLHNYYGDANRNTSQYTGSGKQSAYFISSFPSPSAEESRRSQHGRLYY-PEEVNQGTYDTFGMYLSSPLGYEDAYLDEPVRYPVVSE---RQVLKPNTNYVDFYSTTRRPSYRTQPYPASPDSWV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*.*..: *. . . .: ... . :. **:*.:***********:******* ******.************. ** **:***: ***:: ...***** ** . .: :* **:***** * **:***** .******************.. : *: . :::.*. . . * . :. .******: .* . :.*.*********** ** *. *. ..** .******* :*** *::.*** ** :..:***. **.:: * .: : * *. *. ::..* ** * . . . * :*. ..: * .**.: ***:**** .****** **::**: *:*****: * *** *:*****.**: .*:*:**.** **:* *. ..*:*.****:** *** ***. :::.: **:::.*** :** :..*. :*: . *:..********::*****************:****:***********:****:***::* ** *****:********:.****:**********:**:**:**:.::* ******:*****: *:*****************:***** ****..******:*****. :. :*:*:*:::**********************:***.****:*****:*:*********** ******************:* :**:* ::** *** ::.**::: **** :******: *::**********:* ****.***************************:**********.*:**:***************************.************.***************.**** ****:*****:**:*********:*****:***::***:***.*::***:* *:********************::**********************::*:*:*.*:* ****:*** **::****:**** * : ***..** :* **:.:: *.**.* *. :***:.**: *:.** ** :*** :: .: . *:: :**.** .***.* *: *::*. :: : **..*********.* ****:: **.******", "identical_positions": 728, "similar_positions": 268, "identity": "60.47%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120411-28", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62640-1", "uniprot_id": "GRID1_RAT", "id": "Q62640-1", "name": "Glutamate receptor ionotropic, delta-1", "aln": "----------MEALTLWLLPWICQCVTVRADSIIHIGAIFEENAAKDDRVFQLAVSDLSLNDDILQSEKITYSIKVIEANNPFQAVQEACDLMTQGI-------LALVTSTGCASANALQSLTDAMHIPHLFVQRNPGGSPRTACHLNPSPDGEAYTLASRPPVRLN-DVMLRLVTELRWQKFVMFYDSEYDIRGLQSFLDQASRLGLDVSLQKVDKNISHVFTSLFTTMKTEELNRYRDTLRRAILLLSPQGAHSFINEAVETNLASKDSHWVFVNEEISDPEILDLVHSALGRMTVVRQIFPSAKD-NQKCMRNNHRISSLLCDPQEGYLQMLQISNLYLYDSVLMLANAFHRKLEDRKWHSMASLNCIRKSTKPWNGGRSMLDTIKKGHITGLTGVMEFREDSSNPYVQFEILGTTYSETFGKDMRKLATWDSEKGLNGSLQ-ERPMGSRLQGLTLKVVTVLEEPFVMVAENILGQPKRYKGFSIDVLDALAKALGFKYEIYQAPDGRYGHQLHNTSWNGMIGELISKRADLAISAITITPERESVVDFSKRYMDYS-VGILIKKPEEKISIFSLFAPFDFAVWACIAAAIPVVGVLIFVLNRIQAVRSQSATQPRPSASAT----LHSAIWIVYGAFVQQGGESSVNSVAMRIVMGSWWLFTLIVCSSYTANLAAFLTVSRMDSPVRTFQDLSKQLEMSYGTVRDSAVYEYFRAKG------------------TNPLEQD----------STFAELWRTISKNGGADNCVSNPSEGIRKAKKGNYAFLWDVAVVEYAALTDDDCSVTVIGNSISSKGYGIALQHGSPYRDLFSQRILELQDTGDLDVLKQKWWPHTGRCDLTSHSSAQTDGKSLKLHSFAGVFCILAIGLLLACLVAALELWWNSNRCHQETPKEDKE---VNLEQVHRRINSLMDEDIAHKQISPAS----IELSALEMGGLAPSQALEPTREYQN---------TQLSVSTFLPEQSSHGTSRTLSSGP---------------SSNLPLPLSSSATMPSIQCKHRSPNGGLFRQSPVKTPIP-MSFQPVPGGVLPEALDTSHGTSI", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61627-1", "uniprot_id": "GRID1_MOUSE", "id": "Q61627-1", "name": "Glutamate receptor ionotropic, delta-1", "aln": "----------MEALTLWLLPWICQCVTVRADSIIHIGAIFEENAAKDDRVFQLAVSDLSLNDDILQSEKITYSIKVIEANNPFQAVQEACDLMTQGI-------LALVTSTGCASANALQSLTDAMHIPHLFVQRNPGGSPRTACHLNPSPDGEAYTLASRPPVRLN-DVMLRLVTELRWQKFVMFYDSEYDIRGLQSFLDQASRLGLDVSLQKVDKNISHVFTSLFTTMKTEELNRYRDTLRRAILLLSPQGAHSFINEAVETNLASKDSHWVFVNEEISDPEILDLVHSALGRMTVVRQIFPSAKD-NQKCMRNNHRISSLLCDPQEGYLQMLQISNLYLYDSVLMLANAFHRKLEDRKWHSMASLNCIRKSTKPWNGGRSMLDTIKKGHITGLTGVMEFREDSSNPYVQFEILGTTYSETFGKDMRKLATWDSEKGLNGSLQ-ERPMGSRLQGLTLKVVTVLEEPFVMVAENILGQPKRYKGFSIDVLDALAKALGFKYEIYQAPDGRYGHQLHNTSWNGMIGELISKRADLAISAITITPERESVVDFSKRYMDYS-VGILIKKPEEKISIFSLFAPFDFAVWACIAAAIPVVGVLIFVLNRIQAVRSQSATQPRPSASAT----LHSAIWIVYGAFVQQGGESSVNSVAMRIVMGSWWLFTLIVCSSYTANLAAFLTVSRMDNPIRTFQDLSKQLEMSYGTVRDSAVYEYFRAKG------------------TNPLEQD----------STFAELWRTISKNGGADNCVSNPSEGIRKAKKGNYAFLWDVAVVEYAALTDDDCSVTVIGNSISSKGYGIALQHGSPYRDLFSQRILELQDTGDLDVLKQKWWPHTGRCDLTSHSSTQTEGKSLKLHSFAGVFCILAIGLLLACLVAALELWWNSNRCHQETPKEDKE---VNLEQVHRRINSLMDEDIAHKQISPAS----IELSALEMGGLAPSQALEPTREYQN---------TQLSVSTFLPEQSSHGTSRTLSSGP---------------SSNLPLPLSSSATMPSIQCKHRSPNGGLFRQSPVKTPIP-MSFQPVPGGVLPEALDTSHGTSI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULK0-1", "uniprot_id": "GRID1_HUMAN", "id": "Q9ULK0-1", "name": "Glutamate receptor ionotropic, delta-1", "aln": "----------MEALTLWLLPWICQCVSVRADSIIHIGAIFEENAAKDDRVFQLAVSDLSLNDDILQSEKITYSIKVIEANNPFQAVQEACDLMTQGI-------LALVTSTGCASANALQSLTDAMHIPHLFVQRNPGGSPRTACHLNPSPDGEAYTLASRPPVRLN-DVMLRLVTELRWQKFVMFYDSEYDIRGLQSFLDQASRLGLDVSLQKVDKNISHVFTSLFTTMKTEELNRYRDTLRRAILLLSPQGAHSFINEAVETNLASKDSHWVFVNEEISDPEILDLVHSALGRMTVVRQIFPSAKD-NQKCTRNNHRISSLLCDPQEGYLQMLQISNLYLYDSVLMLANAFHRKLEDRKWHSMASLNCIRKSTKPWNGGRSMLDTIKKGHITGLTGVMEFREDSSNPYVQFEILGTTYSETFGKDMRKLATWDSEKGLNGSLQ-ERPMGSRLQGLTLKVVTVLEEPFVMVAENILGQPKRYKGFSIDVLDALAKALGFKYEIYQAPDGRYGHQLHNTSWNGMIGELISKRADLAISAITITPERESVVDFSKRYMDYS-VGILIKKPEEKISIFSLFAPFDFAVWACIAAAIPVVGVLIFVLNRIQAVRAQSAAQPRPSASAT----LHSAIWIVYGAFVQQGGESSVNSMAMRIVMGSWWLFTLIVCSSYTANLAAFLTVSRMDNPIRTFQDLSKQVEMSYGTVRDSAVYEYFRAKG------------------TNPLEQD----------STFAELWRTISKNGGADNCVSSPSEGIRKAKKGNYAFLWDVAVVEYAALTDDDCSVTVIGNSISSKGYGIALQHGSPYRDLFSQRILELQDTGDLDVLKQKWWPHMGRCDLTSHASAQADGKSLKLHSFAGVFCILAIGLLLACLVAALELWWNSNRCHQETPKEDKE---VNLEQVHRRMNSLMDEDIAHKQISPAS----IELSALEMGGLAPTQTLEPTREYQN---------TQLSVSTFLPEQSSHGTSRTLSSGP---------------SSNLPLPLSSSATMPSMQCKHRSPNGGLFRQSPVKTPIP-MSFQPVPGGVLPEALDTSHGTSI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9P0L3-1", "uniprot_id": "A0A8M9P0L3_DANRE", "id": "A0A8M9P0L3-1", "name": "Glutamate receptor", "aln": "----------MELLVISLSLWILQCRSARADSIIHIGAIFEQNAIRDDEVFQLAISDLSLNDDILQSERITHSIKLIEPNNPFQAVQEACELMNQGI-------LALVSSTGCAAANALQSLTDAMHIPHLFIQRNGDGTPRAECQLNPSPDGERYTLAARPPVRLN-DVMITLVSELRWHKFIVFYDSEYDVRGLRGFLDQASRMGLDVSLQQVDRNVTKVFSTLFSTMRMEELNRYRDTLRRAILLLSPRTAQVFIHQAVETNLASKDSHWVYANEEVSDTEIMELVHSALGRMTVIRQIFPLWRDTNIRCMRNNHRISSLLCDPQEGYLQSLEVSSLYLYDSVLMLANAFYRKLEDRKWHSMASLNCMRKSTKPWNGGWSMLDTIQKGRISGLTGLMDFRSNGANSHVQFEILGTSYSETFGKDVKRLATWDSDRGLNGSLR-ENRADHGMQGITLKVVTLLEEPFVMVAENILGQPKRYKGFSIDVLDALAKILGFKYEMYQVADAKYGSPQANGSWNGMIGELIGKRADVAISAITITPERENVVDFSKRYLDYS-VGILMTKTEERLNIFSLLAPFDLAVWACIAAAIPVVGVMVFLLRRVQSVRSQNPPGPHQPASVTT--SFQSAIWIVYGAFVQQGGESFMSSMALRIAMGSWWLFTLIVCSSYTANLAAYLTVSRMDNAIRTFQDLSKQSEINYGTVRESAVFEYFRVKG------------------TNPLEQD----------STFAELWRTINKNQGQDNSVTSPAEGIRKVKRDPYAFLWDMAVLEYAALTDDDCTLVVTGNGMSSKGYGLALQHGSPYRDLFSQKILDLQEKGDLDILKQKWWPRKGRCDLDKHAEPQTEGRALRLHSFAGVFCILAAGLLLACLVAALESWWNGPRCQRAQPKEDTKGCALEMASGSLAYNEIAPAAGCARDVWPERERDWEDTQAFYTGQRGESGAGSPPFEWADGGRSGTQAAARSASGDLCPGHGQHAAAAELPGGPERFSPWGPVRDLVPPGGSWGRPRARTEPPPPSQQFHSAALHALQTPGAQRRPFPPEPRKDTYAHLLPGSARGTHPRSH", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "E9NA96-1", "uniprot_id": "IR25A_DROME", "id": "E9NA96-1", "name": "Ionotropic receptor 25a", "aln": "MILMNPKTSKILWLLGFLSLLSSFSLEIAAQTTQNINVLFINEVDNEPAAKAVEVVLTYLKKNIRYGLSVQLDSIEANKSDAKVLLEAICNKYATSIEKKQTPHLILDTTKSGIASETVKSFTQALGLPTISASYGQQGDLRQWRDLDEAK--QKYLLQVMPPADIIPEAIRSIVIHMNITNAAILYDDSFVMDHKYKSLLQNIQT----------RHVITAIAKDGKREREEQIEKLRNLDINNFFILGTLQSIRMVLESVKPAYFERNFAWHAITQNEGE---ISSQRDNATIMFMKPMAYTQYRD-RLGLLRTTYNLNEEPQLSSAFYFDLALRS--FLTIKEMLQSGAWPKDMEYLNCDDFQGGNTPQRNLDLRDYFTKITEPTSYGTFDLVTQSTQPFNGHSFMKFEMDINVLQIRGGSSVNSKSIGKWISGLNSELIVKDEEQMKNLTADTVYRIFTVVQAPFIMRDE---TAPKGYKGYCIDLINEIAAIVHFDYTIQEVEDGKFGNMDENGQWNGIVKKLMDKQADIGLGSMSVMAEREIVIDFTVPYYDLVGITIMMQRPSSPSSLFKFLTVLETNVWLCILAAYFFTSFLMWIFDRWSPYSYQNNREKYKDDEEKREFNLKECLWFCMTSLTPQGGGEAPKNLSGRLVAATWWLFGFIIIASYTANLAAFLTVSRLDTPVESLDDLAKQYKILYAPLNGSSAMTYFERMSNIEQMFYEIWKDLSLNDSLTAVERSKLAVWDYPVSDKYTKMWQAMQEAKLPATLDEAVARVRNSTAATGFAFLGDATDIRYLQLTN--CDLQVVGEEFSRKPYAIAVQQGSHLKDQFNNAILTLLNKRQLEKLKEKWWKNDE--ALAKCDKPEDQSDGISIQNIGGVFIVIFVGIGMACITLVFEYWWYR---YRKNPR------IIDVAEANAERSNAADHP----------------------GKLVDGVILGHSGEKFE-----------KSKAALRPRFNQYPATFKPRF--------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * . *:: :*..:* ::. .: . : : *:.:* . : . : .:. :: *: .* * * ::.. ::::::*:*:*: :* : . . * * .*: : : * * **. : :.: :* .:. : ::**..: : * * : ::: .::. . : *:::: *: . :::*.. : :: ::*:. .:: * .:: .: :. :. * : :. :* . *..:.:.. .. *:: * :* . :: :.*: :.:* : ..: . * ::. . : .: :. . * : :* : .. : .:::* . : : :..* * . : :: *. . . ::.*::: **:* * ** ***:.**::: :* : *.* : :. *.::* * .***:: :*:.*:**:.:.:::: .*** *:**: * * : *:: :... .:*.::: :: ** ** ** ....::::: * .. *. . . ::..:*: ::. *** . ..:: *:. .:**** :*: :********:*****:*..:.:::**:** :: *..:. *:. **. . ..:*:. ..::::*:::.: . :. ... :*** * : :.* **: * : * *: :* * *.:*:*:** :* *.: ** * :. :*: **:*** . * . ..: :. .: ::.:.*** :: *: :**:. .:* ** : *: ::: . .. * . * : : . : * ..: :: ", "identical_positions": 166, "similar_positions": 362, "identity": "15.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120411-42", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHT3-1", "uniprot_id": "D3ZHT3_RAT", "id": "D3ZHT3-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTHTRRKS--LPMLSSGPTGRGEPLQMEDSNVEQGAEDVEPG----MPESPGHLTGR-RKNYPLRKRS-LVPEKPKACKVLLTRLENVAGPRS---------------------ADEADELPPDLPKAPSPTPSSEDA------GLVQPRKRRLASLNAEALNNLLLERED-----------------TSSLAGARRSRGGDPHRSRDR--ATGSWS----------------------------------------------------------------------------------------------FSKKRPRLGDLGEGSRDLSPELAPDEGARRDGD----PAPKRLASLNAAAFLKLSQERE---------------------------------------------------LPLRPSRAQAEADGRSTEPLAPKVLR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKVNGKNCPKVRQGAGSGEATGPPNWQEQPEERWPSAPPRGPPIQPSHQAPGKALENPL--RPNLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPAPQLAPLP--------------------MPGNPADYSGPCGGPELTALGGFYLYCGQDGLQCGSYSPCPMLPEGKLSP---VAAP-NEGLLMAPSSVPSG---------------------------------------------------------------------------------------------------------------------------VPFQHPPWSASR-YCSSEDTGANGYSICGVLPLSLTHIGTTCG------------------------------------------GCPYKMPFTAG-CRSLGQLEFPLPEAGHPASPAHPLLGCP-----------------------------------------------------------------------------------------------------------------------------------------------------VPSVPPAAEPIPHLQTPISEPQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TVARACPQSAKPPSGSKS----------------------------------------------------------------GLRTGSSCRHTVRSKAARRPSHPKQPRAQRPR-------------------------------------------------PRRRRRRR------------------------TNGWVPVGAACEKAVYVLDEPEPAIRKSYQAVE-RHGETIRVRDTVLLKSGPRKTSTPYVAKISALWENPESGELMMSLLWYYRPEHLQGGRSPSMHEPLQNEVFASRHQDQNSVACIEEKCYVLTFAEYCRFCAMAKRRGEGLPSRKTALVPPSADYSTPP-HRTVPEDTDPELVFLCRHVYDFRHGRILKNPQ---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q497V6-1", "uniprot_id": "BAHD1_MOUSE", "id": "Q497V6-1", "name": "Bromo adjacent homology domain-containing 1 protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTHTRRKS--LPMLSSGPTGRGEPLQMEDSNMEQGTEDVEPG----MPESPGHLTGR-RKNYPLRKRS-LVPEKPKACKVLLTRLENVAGPRS---------------------ADEADELPPDLPKPPSPTSSSEDA------GLVQPRKRRLASLNAEALNNLLLEREE-----------------TSSLAGARRSRGGDPHRSRDR--ATGSWS----------------------------------------------------------------------------------------------FSKKRPRLGDLGEGSRDLSPELAPDEGARRDGD----PAPKRLASLNAAAFLKLSQERE---------------------------------------------------LPLRPSRAQAEADGRSTEPLAPRILR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PKVNGKNCPKARQGAGSGEATGPPNWQEQPDERWPSAPPHGPPTQPSHQAPGKALENPL--RPNLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPAPQLSPLP--------------------MPGNPADYSGPCGGPELTALGSFYLYCGQDGLQCGAYSPCPMLPEGKLSP---VAAP-NEGLLMAPSSVPSG---------------------------------------------------------------------------------------------------------------------------VPFQHPPWSAPR-YCSSEDTGANGYSICGVLPLSLTHIGTTCG------------------------------------------GCPYKMPFTAEGCRSLGQLEFPLPEAGHPASPAHPLLGCP-----------------------------------------------------------------------------------------------------------------------------------------------------VPSVPPAAEPIPHLQTPISEPQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TVARACPQSAKPPSGSKS----------------------------------------------------------------GLRTGSSCRHTVRSKAARRPSHPKQPRAQRPR-------------------------------------------------PRRRRRRR------------------------TNGWVPVGAACEKAVYVLDEPEPAIRKSYQAVE-RHGETIRVRDTVLLKSGPRKTSTPYVAKISALWENPESGELMMSLLWYYRPEHLQGGRSPSMHEPLQNEVFASRHQDQNSVACIEEKCYVLTFAEYCRFCAMAKRRGEGLPSRKTALVPPSADYSTPP-HRTVPEDTDPELVFLCRHVYDFRHGRILKNPQ---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8TBE0-1", "uniprot_id": "BAHD1_HUMAN", "id": "Q8TBE0-1", "name": "Bromo adjacent homology domain-containing 1 protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTHTRRKS--LPMLSSGLTGRREPLQMEDSNMEQGVEGVEPG----MPESPGHLTGR-RKNYPLRKRP-LVPEKPKACKVLLTRLENVAGPRS---------------------ADEADELPPDLPKPPSPAPSSEDP------GLAQPRKRRLASLNAEALNNLLLERED-----------------TSSLAGTRRSRAGDPHRSRDRDRATGGWS----------------------------------------------------------------------------------------------SSKKRPRLGDLGGGSRDLSPEPAPDEGPRRDGD----PAPKRLASLNAAAFLKLSQERE---------------------------------------------------LPLRLPRAHAEVDGRSTEPPAPKAPRP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQPLSKALESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSPLP--------------------MPGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSP---VAAPHEEGLLLAPSSVPSG---------------------------------------------------------------------------------------------------------------------------TPFQHPPWGSSR-YCSSEDTGVNGYSICGVLPLSVTHAGTTCG------------------------------------------GCPYKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLLGCP-----------------------------------------------------------------------------------------------------------------------------------------------------VPSVPPAAEPVPHLQTPTSEPQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TVARACPQSAKPPSGSKS----------------------------------------------------------------GLRTGSSCRHTARSKAARRPSHPKQPRVQRPR-------------------------------------------------PRRRRRRR------------------------TNGWVPVGAACEKAVYVLDEPEPAIRKSYQAVE-RHGETIRVRDTVLLKSGPRKTSTPYVAKISALWENPESGELMMSLLWYYRPEHLQGGRSPSMHEPLQNEVFASRHQDQNSVACIEEKCYVLTFAEYCRFCAMAKRRGEGLPSRKTALVPPSADYSTPP-HRTVPEDTDPELVFLCRHVYDFRHGRILKNPQ---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PPC4-1", "uniprot_id": "A0A8M9PPC4_DANRE", "id": "A0A8M9PPC4-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSITAQVFFLAVVNTASHSSVAASGVSSLTVLQPRYLLVRTFGFAWQSVMTHARQRNSLCGYKSESADQVNCRITMDRTWPEKKAKRCSTQR-GKAKEVKGKSAERDRKLYPLRGRHGLGEVSALNCCVVLTRLDESETCRNGMKAQVKEMQGKSKICKCRKKACKSCKAAEPKSKVKPDKSALYTE------FILEPRQRRLASLNAEAVNSLLLDRVDP--------------QQTSKPSKKQQQTKGDPSLSKDTAKDNDCPR----------------------------------------------------------------------------------------------KSQDNRKRGCTGETEQNRNPKKAKTESDTIDLQTLNSPAPKRLAGLNAAALLKLTSTSS---------------------------------------------------AGKRRGKTEGKPSAGGVRGKQLLSKS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RKQQHNLACQSTLKVSQQCCSFCEKHALHNEALWDGSTGSHGFISPGYQCR-SMLGFPLKPVKEEKTETDVKSYYCCSQERSVEYCHRLALFLGQKPFPETDEHSLKGFLP----------------SPHTLTHSAMPIGAHPYPCYPGYYVHIAHHGTPSLPVSSNQGSHPPSSVPPLKMCSSGVQRPKLLPSTVSHP---------------------------------------------------------------------------------------------------------------------------TGIPHPAYCNSVGTCYGEACRLSSYAYRPTQPITSRGCSYNAG------------------------------------------CSSCMHKMETEDYSYP----LDDRSSSITMPSALPLSICP-----------------------------------------------------------------------------------------------------------------------------------------------------ISSVPPPTQSVPHLQTPLPDTGR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SQVQIRVGRECPQRAKPPSGSRS----------------------------------------------------------------GVRDSAVCPHIKDGQLG-----SGHGSGAAKQ-------------------------------------------------SKISRRRA------------------------TNGWLPVGVATEKEVFIVAEDSASLRRCYEGVQ-RDGEVIRVRDTVLLRSGPRKKSLPYVAKVSAFWDDPESGELMMSLFWYYRPEHTQGGRIPSMHC--ENEIFASRHQDENSVACIEDKCYVLTLAQYCRFCALVKCREEGFPKR-SPLVPPSS-YVIPA-HRCVPNDIDPDLVFVCRHVYDFRYGRLLKNLQ---------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VWC0-1", "uniprot_id": "Q9VWC0_DROME", "id": "Q9VWC0-1", "name": "", "aln": "MVSKKRSNAAERVQRSTATAAAAAAAAAAAATASSTQGKKRPGKQTKASGGGGDEADDKKSASKTDSAAKKPAKDPTGSSGVSTATTEGGAGNGGGKQTTSTTTSSTSSTTAPSASASASASNSLKLSPEERHEDGKARAINKMLKSLDIKIHGFDNLLPSGEERLNDGVLKSSISENVKTKSRAAAVKVISSLNPGKMPPVKRVRPSPEPVREKVAEKPAEKVLDKEKPKAEQQITPPPAPEESPASKVPKKTVQQAKKAKVESSLVQATVLTTTSAATSAPSSASTSKHTSTKNPGKKSAHSEQMPKKELSKLAKMGKPKKEANLVKSTARLPDSNTESVQMELEEIVSTPTVTPTPSATPTATPTPTATPTLTPTPTATRTRTPTPTLTPTPTPTSTPSSTAIAAGQPAPPPPPPGGAPKQRPKVKYTKTSAGSKGRMQQALNQKAPAASWSGAKDIYDFKSGSEDEEPIKMVLPSLKELREFSDEDNKPLKLFERQAEKTKVQVQDEEEQPLVKKEEKPPSEKEVKVKSKEKEKEKEKDVDPLSNAQQSEPAAKHTTSTSTTSTTSITSVKKQAKRKIATPMPSSAGRKKKTVGKGKAAAAKEPPPSGSSAESSSSEDERKLSAYSGPKRHRMASLNALAKVQCLYENESRTAHELGLSKATQQPPRIRTLDGSDDDNHKDSPRHGDTDRDKGSVSPPHTSAAPPAAPIAPPKEAEPRRELRYVPGGRGVGKHWEFDSDSETEELQLQQTLPPVKKKKLPKKAPPKKVASSETDAKRKKKSVQVEESDDEEAKEKEKEKEKPKPPKQLPKKRKTAFTEELIGDYKGILARKRMASLNASAIVAATYEVERHLDKNLASDCSSFESYDELDTMPTTTSKVTSAAAIKTEVIHIKKEPKESKESLRERERERESERRRERDNELKDSTVGKMSSHSIIEESNDSKYSKETKETNTDTTITTTGYRDSAASTKDAKDCSRPTSSSVVIVQDTDVTITGVYVNASNGAAQEAYCKMQYRVQSSVTEERVLRPGSVEPPKSYTPLSALSSMLPPGASSGLSEAHSSPPLPVHAAPTGPHVLLPGEHLSAGMYHAPDLGLHTEHALPDHHGPPPPSYAAAAAAAAAAAAYHAHQLAPGGGGVLHMHHQHQYAAHAAHAHHYQQAAEYHGGPPPPPHHYGGPPPQGHYGPPPGAPVPVPVAVPNTVTVPPERCDVGSPPPSYRASAYPPPSSVGMPPPTLGGGSSAFCAPSPLHHHQHQHQQPGPGVGPPHHDPSGYYQPAGPLISPHVIAAPPPPAQVKKLQEEDGPVSAAGSPTQLQQQQAAAEAAAAAADQAAAQSQSQSQGQSHGHAHSHAHNPQQAQHPPQPQPYPAGAVAAAAAAAAAHQGVPYSRSMHAAQMHYSTGYPPNYYAPYPGEVMCYSPPTYPPYFSSKVYQPSHPAHPAAHPQGPPPPGAYRRYPYYQHAGPPPPHELYEQQPPPPPVSSGSVSGPAQQQPPTSSPASVGAAGAGTAGAPSGSQLVPAHQQQHQQQHLEHYPGPPSYYAGYSPGGGASAGQCYTRGLQGPYMEYPPQCPCPMPQSCPKNVHTGPHIGSNIISNIDQSSSCSSSMLLSATSNSNIGGGSSSSSSSSSSTTLPACSSATTTTTASALTTSRGPVKNVTPNNSNSSGHTSTNSCRSSNNSNNSSNSSCQTIEMTSWATAATNTTSTTATTATTGTQCQMLVKTELKGENPQVTKMQYEAHVMPPPTPPESYCASDEKLLDDQEQEAELELRLRLGLGLEKSHGGQQHIEAYDLTCSTPPPVTVPQAAAVPRKARIGKSMAREMVYAAQQQLLPEKQLKQPKEAAAKLEAEPEMPFVLKAEIKAETKIKIEHDGEAQASTHISQLPDLKPTIKTEPEQELEQEAASVPSVAKTEPQPEVEVEREQQEPPVDEEQQPTPGGSKQRFNLLALSSGNKKTKTNNSYKSLIKQAEPKSYLCPGRRFIRRHGRAPAKYVKRRQMILTQRQQQRMRLQRREQQQQRRQQREAAAEVVAGAVVTPSLAGNPIEQAGSEVSIVKDQAPNSSATPSASPKRARPRKQEIAALHLLEGLDTTLSRGYFSDPELNHSSRKQAPTAVGGLYAASSPLTTATDHRGKQTTAEKRSKSETKKPPSGESSESGLPCKKPRKEPAGKVKGKGKKTTAGAAATTIASTAETQTEAVNAITASNQETNNNEYQTADLQAQKFRECPAVTDAKVAGTATSTSTASQQQNQQHSDEQHQFLVPSQPATASATAALAATPPPSRQGQATHTKRTRSRCKFGNRKRQRHRPGGVSYELDVTQPPATKANVVPKWNNGWMWAGKAFQGAVFLNSDDPLVLRTCYPAMRHVEGDIIRIRDCVLLKAN-EDNELPYVAKVAHLWQNPEDGEMMMSLLWYYRPEHTDQGR---QRNDCPDEVYASRHRDHNSVACVEDKCYVLTFSEYCRYRRRLRAAEEDVEDVSIVPRRPSIATAPGFPVRTVPEHTNPELVMFCRRAYEFRTRRLLKLPHKNGLVCSSS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . . . : : : . : : : :. ** . * . :. . . . . : *:::*:***** * . * :. . . . *. * .. ::.. : :: : : * **:*.***:*:: : . * . . : . . : . .: : . . : . * : . . . . :* . * :. . . * : : * . .. : *::* *. . .. . . . * . . .. . : .: ..: * *. .***. ::. *: :. * .: *****. * : * .: . . : : :*: .***: .* * : *:: : :* .* .:. .*: **:** ***::. .... *****:: :*::**.**:****:******* : ** : :*::****:*.*****:*:******:::***: : *.. . ** * **:. :*:**:.**:.*:** *:** : ", "identical_positions": 124, "similar_positions": 182, "identity": "4.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120411-43", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ACD4-1", "uniprot_id": "D4ACD4_RAT", "id": "D4ACD4-1", "name": "Pseudouridylate synthase RPUSD2", "aln": "--MTPSYRDPEAACHAVMWRSVPGCLRYIVQWQVALWSHS-FVRTWGSCGKAMTEALSAQAEAAD-------GLKALIEQNGDTGSDTRGEPHLELLEPAT-------------------------------------------------------------------------------------------------------------VGKQVPESGEQAQGGEEQLPGNGEQAPTPVAD------SGKRKKRRG----ATGERVVPPPKKRRTGVSFSDEHFAETTYYFEGGLRKVRPYYFDFQTYCKGRWVGRSLLHVFSTEFRSQPLAYYEAAVRAGRLHLNEE-----PVQDLNIVLKDNDFLRNTVHRHEPPVTAEP---------------IRLLAENDDVVVIDKPSSIPVHPCGRFRHNTVIFILGKEHQLKELHPLHRLDRLTSGVLMFAKTAAVSEKIHEQVRDRQLEKEYVCRVAGEFPDKEVICKEP----------ILVVSYKVGVCRVDPQ---------GKPCETVFQRLSYNG--RSSVVQCRPLTGRTHQIRVHLQFLGHPILNDPIYN-STAWGPSRGQGGHIP-KTDEELLRDLVAEHQAKESLSMLDLCEGDLA---------PG------LIDSTAPSSELGKD-----SLEG---LATAAQKIDG-------------MVDEASQHPDT----PGKAAKADVS--------QQTDPLCAECR-VLRQDPLPQDLVMFLHALRYK---------GPDFEYVSPIPAWAQADWQED---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q149F1-1", "uniprot_id": "RUSD2_MOUSE", "id": "Q149F1-1", "name": "Pseudouridylate synthase RPUSD2", "aln": "-----------------MWRGVPGCLRDIVQWQVALWSHS-FVRTWGSCGKAMTEALSAQAEAAG-------GLKALVQPNGDAGSNTSGEPLLERLEPAA-------------------------------------------------------------------------------------------------------------VGKQVPESGDQAQGGEGQLPSNGEQTPAPVAD------SGKRKKRRG----ATGERVVPPPKKRRTGVSFSDEHFAETTYYFEGGLRKVRPYYFDFQTYCKGRWVGRSLLHVFSTEFRSQPLSYYEAAVRAGRLHLNEE-----PVQDLSIVLKDNDFLRNTVHRHEPPVTAEP---------------IHLLAENNDVVVIDKPSSIPVHPCGRFRHNTVIFILGKEHQLKELHPLHRLDRLTSGVLMFAKTAAVSEKIHEQVRDRQLEKEYVCRVAGEFPDKEVICKEP----------ILVVSYKVGVCRVDPR---------GKPCETVFQRLSYNG--RSSVVQCRPLTGRTHQIRVHLQFLGHPILNDPIYN-STAWGPSRGQGGHIP-KTDEELLRDLVAEHQAKESLSMLDLCESDLT---------PG------LIDSTAPSSELAKD-----SLEG---LATAAQKIDG-------------IAEAAPQHLDT----PEKAAKADVT--------QETDPLCAECR-VLRQDPLPQDLVMFLHALRYK---------GPDFEYVSPIPAWARDDWQED---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IZ73-1", "uniprot_id": "RUSD2_HUMAN", "id": "Q8IZ73-1", "name": "Pseudouridylate synthase RPUSD2", "aln": "-----------------MWLDRRGWLRVLGHWRYDLRRPS-FTRTWSGDKGPMAETVSTQVGTEG-------GLRASHQQNGDAGGDAKVE--LSPGPPKP-------------------------------------------------------------------------------------------------------------AGREVEP-----------APVGGEHPSAAAPG------PGKHKKRRG----ATRERVVPPPKKRRTGVSFGDEHFAETSYYFEGGLRKVRPYYFDFRTYCKGRWVGHSLLHVFSTEFRAQPLAYYEAAVRAGRLQLNEK-----PVQDLNIVLKDNDFLRNTVHRHEPPVTAEP---------------IRLLAENEDVVVVDKPSSIPVHPCGRFRHNTVIFILGKEHQLKELHPLHRLDRLTSGVLMFAKTAAVSERIHEQVRDRQLEKEYVCRVEGEFPTEEVTCKEP----------ILVVSYKVGVCRVDPR---------GKPCETVFQRLSYNG--QSSVVRCRPLTGRTHQIRVHLQFLGHPILNDPIYN-SVAWGPSRGRGGYIP-KTNEELLRDLVAEHQAKQSLDVLDLCEGDLS---------PG------LTDSTAPSSELGKD-----DLEE---LAAAAQKMEE-------------VAEAAPQELDTIALASEKAVETDVMN-------QETDPLCAECR-LVRQDPLPQDLVMFLHALRYK---------GPGFEYFSPMPAWAQDDWQKD---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1P3Z9-1", "uniprot_id": "A0A8M1P3Z9_DANRE", "id": "A0A8M1P3Z9-1", "name": "Pseudouridylate synthase RPUSD2", "aln": "----------------MVHVWKITHIQALTLLRFGRRQNSEFIKRVYQNRNVSVETQRTHCSVLN-------VRRNSTQVES---SKHPVNTHLSLYDMDN-------------------------------------------------------------------------------------------------------------KGEEGGGDTDSTVKTSCGKRKNEETDEAAGQC------SGRKRKRGGGKQLRPGERYVPPPQKRNTGVSFNQEHFAETSYYFEGGLRKVHPYYFDFKSYCKGRWIGKTLLDVFKKEFRAESLDYYNAAVKEGRIKLNET-----PVDDLNVVLKNNDLLRNTVHRHEPPVCGQP---------------LKLLVDDGEVVVVDKPSSLPVHPCGRYRHNTVIFILGKEKGLVGLHTVHRLDRLTSGVLLFARTLEVSKKLDVMVRERQLEKEYVCRVEGEFPEAEVVCEEP----------ILVVSFRVGLCRVDPK---------GKESRTIFQRLSFNG--RSSVVRCRPLTGRTHQIRVHLQFLGFPILNDPIYG-SSAWGPNRAKGGLVG-MSDEELLEALIEEHRSKESLHLLDLPDEEVSGKTKCKDGAQGRNEQITAIESSSGSSEVSLD-----EVKAESRQVVQQSTSES-------------VGEINGARKDK-DLASDDASRTGRSKD------FVRDHLCGECK-IVRPDPTEKELIMYLHALRYK---------GPDFEYSTQLPDWAKEDWIQD---------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VKU8-1", "uniprot_id": "Q9VKU8_DROME", "id": "Q9VKU8-1", "name": "Pseudouridylate synthase RPUSD2", "aln": "MESS-------------------KLLRNAQTQHGDASSVD--VENIFLHR----HMLYTNPTSD----------------GNLHDREDSPECVWCPDDKDG-----------------------SPAE------------------------------------------------------------------------------------SKDPP-----------ISISEEKSETQSKE----VLSEKRKASSTDDEGHVKKVKLEANSLKTKRPGFSDERYDETSYYFENGLRKVYPYFFTFTTFAKGRWVDEKILDVFVREFRAAPPEEYERSLEAGKLTVNSE-----KVP-KDYKIKHNDLLANVVHRHEVPVTSQP---------------IKIVYMDKDIVVVNKPASIPVHPCGRYRHNTVVFILAKEHNLKNLRTIHRLDRLTSGLLLFGRTAEKARELELQIRTRQVQKEYVCRVEGRFPDGIVECNEK----------IDVVSYKIGVCKVSPK---------GKDCKTTFKRIGEVG--SDSIVLCKPLTGRMHQIRVHLQFLGYPISNDPLYN-HEVFGPLKGRGGDIGGITEEQLISNLISIHNAENWLGLE--GDQIVSG--EIKDVAAS-----TSVV-EAPSVVQAP-----INSETEKPVISKNLEPSN--------------DATAQIATQTCYEEPDRSFDS---------KKTTSDPQCSECK-INYRDPGTKDLIMYLHAWKYK---------GVGWEYETELPEWACNSNIDYDKV------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VKV0-1", "uniprot_id": "Q9VKV0_DROME", "id": "Q9VKV0-1", "name": "Pseudouridylate synthase RPUSD2", "aln": "MQNSPAPCAWYLPWSLAAQQHQQKMLQMQSPFLDKMGATS--VGGIFAGQPQMQQQLSPNTAAAPPANYQQPALHPSAAPGAPHFHMGSPYSHLAPQLLNAGQLNQNALMHSAMFSSLPLGAYYAPAAGAGHSAFGGVPLTTAAQQSLLAATGGATAGHLANQQTTAQVPVQVPVQMAQRTAPAACSMVQPLNCLPHQELNHLSSINLNLLRSPAPPLPAIQVLPSAEVPINKKTTSPRDSENLKIKVPEKRKTDDNDQIKELKKAKLETKALKAKRPGFTDERYQETSYYMENGLRKVYPYYFTFTTFTKGRWVGEKILDIFSREFRAHPAEEYERCIQTGTLTVNFE-----KVP-IDYRLKHNDLLANIVHRHEVPVTCQP---------------IKIVHMDEDIVVVNKPASIPVHPCGRYRHNTVVFILAKEFNLKNLRTIHRLDRLTSGLLLFGRSPKKARQMEQQIRNRQVEKEYICRVEGVFPDGIVECKEP----------IEVVSYKIGVCKVSAK---------GKDCTTTFQKLSQNG--TTSVVLCKPLTGRMHQIRVHLQYLGYPILNDPLYN-HEVFGPLKGRSGDIGGKSDEELIRDLINIHNAENWLGID--CDSDISMFKSTKDEADR-----ESLSSEHTSVVHHSDDDGCVNSRETTPPCNEPQQPENSVKLLETTNAVKEYQVAAQKSSSEICPAPLDAVESPLNGGGCNVGKVTVDEHCYECK-VHYRDPKSKDLIMYLHAWKYK---------GPGWEYETELPNWARNDWDHLDSA------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q12362-1", "uniprot_id": "RIB2_YEAST", "id": "Q12362-1", "name": "Bifunctional protein RIB2", "aln": "-------------------------MEDSN-----------------------------NEASDDFN-----------------------------------------------------------------------------------------------------------------------------------------------------------------NLLNKEIESAKEVK---LRKFANRNNNRNENSSKVKDASGFRLRVIQTDGHKTKKTDPDYEVTIDGPLRKIEPYFFTYKTFCKERWRDRKLVDVFVSEFRDREPSYYSKTIAEGKVYLNDE------PANLDTIIRDGDLITHKVHRHEPPVTSKP---------------IDIVFEDEDILVIDKPSSIPVHPTGRYRFNTITKMLERQLGYS-VHPCNRLDKPTSGLMFLAKTPLGADRMGDQMKAREVTKEYVARVKGEFPIGIVEVDKP-------VRSVNPKVALNAVCEMSDE--------NAKHAKTVFQRVSYDG--QTSIVKCKPLTGRTHQIRVHLQYLGFPIANDPIYSNPDIWGPDLGRGGLQNYDDIVLKLDAIGKTNPAESWIHPHS-EGEYLL------------------------------------------------------------------------------------------------------GRQCEECEAEMYTDPGTNDLDLWLHAFRYESLERNSDTQKPLWSYRTKYPEWALEPHRRYMEMAVKEAGKCGPTKTAFSVGAVLVHGTQVLATGYSRELPGNTHAEQCALIKYSQLHPNCPTIVPMGTVLYTTMEPCSFRLSGNEPCCDRILATQGAIGTVFVGVMEPDTFVKNNTSLNKLESHGVNYIQIPGYEEECTIIAFKGHDNSDDKA", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "Q12069-1", "uniprot_id": "PUS9_YEAST", "id": "Q12069-1", "name": "tRNA pseudouridine(32) synthase, mitochondrial", "aln": "-------------------------MQRNNRLRNLFTVPVIMARQLKRNALSAGLAFAGNATSNEFD-----------------------------------------------------------------------------------------------------------------------------------------------------------------EHLQNEVEREREIQ---KKKKIKRTQSK--KSPDLINKSTFQSRTIGSKKEKHRQLDPEYEIVIDGPLRKIKPYHFTYRTFCKERWRDKKLVDVFISEFRDRESEYYKRTIENGDVHINDE------TADLSTVIRNGDLITHQVHRHEPPVTSRP---------------IKVIFEDDNIMVIDKPSGIPVHPTGRYRFNTITKMLQNNLGFV-VNPCNRLDRLTSGLMFLAKTPKGADNIGDQLKAREVTKEYVAKVVGEFPETEVIVEKP-------LKLIEPRLALNAVCQMDEK--------GAKHAKTVFNRISYDG--KTSIVKCKPLTGRSHQIRVHLQYLGHPIANDPIYSNDEVWGNNLGKGGQADFDIVITKLDEIGKRKPAKSWFHSNGGYGEVLR------------------------------------------------------------------------------------------------------QEKCSICESDLYTDPGPNDLDLWLHAYLYESTETEEGTEKKKWCYKTEYPEWALRR-------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P53294-1", "uniprot_id": "PUS6_YEAST", "id": "P53294-1", "name": "tRNA pseudouridine(31) synthase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTIKVIEVYTQNGLRKVRPYYNRRSAFVKGRWLGKLLIDVLVSEFKLRPRAYYLDQIRKGTYRLIRDGVPLVPDHLMTTIIKNHDVLETTTHKHEPPVKQWCSQEVEAEDLPGRIAGFNIVFEDESILVIDKPSGIPVHPTGQFYQNTITELLK-LHGVD-ALPCYRLDKITSGLLILAKNSQSAGEIQKSIRSRDMIKIYLARVKGRFPHSELILDNENAAETTFEDTSKVTVEMTPIYSIDPKRQFPVGLSTSKDAITKFYPIRYFSHADETVVACKPITGRTHQIRIHLARLGHPIVNDSVYCSHITKYPERLKFITQFPRWENQQDLDAEELKVRFQKFVDETKNNCRTM------------------------------------------------------------------------------------------------------ETFCPECHTVDLKDPVLSDLELWLHAWKYEEING-------KFKFKTDLPKWAQLDNS-----------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :. ***: **. :: * ** .. ::.:: **: * : * : ::. *.: .*:** ** : :: : .::*::**:.:**** *:: **: :* . ***: ***::::.:. : .: :: *:: * *:.:* * ** : .: : :. . .* . * * : . ::* *:*:*** ****:** **.** **.:* : : . : * *. ** .:* ::*** *: : : : * ** ", "identical_positions": 76, "similar_positions": 91, "identity": "7.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120411-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6UXY8-1", "uniprot_id": "TMC5_HUMAN", "id": "Q6UXY8-1", "name": "Transmembrane channel-like protein 5", "aln": "MSAYYRNNWSEEDPDYPDYSGSQNRTQGYLKTQGYPDVPGPLNNPDYPGTRSNPYSVASRTRPDYPGSLAEPNYPRSLSNPDYSGTRSNAYSAASRTSPDHPTSLPEPDYSEFQSHPYHRASSRQPDYPGSQRNPDFAGSSSSGNYAGSRTHPDHFGSLEPDYPGAQSNSDHPGPRANLNHPGSRKNLEHTSFRINPYADSLGKPDYPGADIQPNSPPFFGEPDYPSAEDNQNLPSTWREPDYSDAENGHDYGSSETPKMTRGVLSRTSSIQPSFRHRSDDPVGSLWGENDYPEGIEMASMEMANSYGHSLPGAPGSGYVNPAYVGESGPVHAYGNPPLSECDWHKSPQGQKLIASLIPMTSRDRIKAIRNQPRTMEEKRNLRKIVDKEKSKQTHRILQLNCCIQCLNSISRAYRRSKNSLSEILNSISLWQKTLKIIGGKFGTSVLSYFNFLRWLLKFNIFSFILNFSFIIIPQFTVAK--KNTLQFTGLEFFTGVGYFRDTVMYYGFYTNSTIQHGNSGASYNMQLAYIFTIGACLTTCFFSLLFSMAKYFRNNFINPH-IYSGGITKLIFCWDFTVTHEKAVKLKQKNLSTEIRENLSELRQENSKLTFNQLLTRFSAYMVAWVVSTGVAIACCAAVYYLAEYNLEFLKTHS-----NPGAVLLLPFVVSCINLAVPCIYSMFRLVERYEMPRHEVYVLLIRNIFLKISIIGILCYYWLNTVALSGEECWETLIGQDIYRLLLMDFVFSLVNSFLGEFLRRIIGMQLITSLGLQEFDIARNVLELIYAQTLVWIGIFFCPLLPFIQMIMLFIMFYSKNISLMMNFQPPSKAWRASQMMTFFIFLLFFPSFTGVLCTLAITIWRLKPSADCGPFRGLPLFIHSIYSWIDTLSTRPGYLWVVWIYRNLIGSVHFFFILTLIVLIITYLYWQITEGRKIMIRLLHEQIINEGKDKMFLIEKLIKLQDMEKKANPSSLVLERREVEQQGFLHLGEHDGSLDLRSRRSVQEGNPRA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FDU7-1", "uniprot_id": "E7FDU7_DANRE", "id": "E7FDU7-1", "name": "Transmembrane channel-like protein", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MRRMSVYPQHGTALENLGLTAHEIQQEVENN---------------------TSELVSDLSDLSAGARFQAIRSLPMSYNERKAIRNRVNN--IKLSKTILPT----DCRQQVSLSFRRFRASLTSARQRLVVWQDTLKEIGGRFGTSVLSYFLFLKWLLKFNVFSFVINFCFITIPQIVHAPNISHVTGFRGLELLTGVGYFNQTVLFYGGYDGEVIVS---KPAYNMQLAYFFTIAAYMVLCGLSLIYSMSRSFQKNFVLETGPVSGGAWRLLCSWDFSVVNEKAIQYNKNNLGIQLKESLSERLQMKNKISLSDRIKHLSLNLVAWLLCLLLALGSGAGIYFLGTEQLTFSFNQDPNDLVSEASTLLLPVVVSLINLIVPLLYSLIGKMETYSNPRAKIYISIARNIILKMSLLGILCFYWLNFVP-DKIPCWESFVGQSVYRLLIIDFIFCLLGIFFGEFLRNVIGTMCIQSLGVPEFDIARNVLDLIYAQTLAWIGIYFSPLLPVMQVLKLFIIFYLKKLSLSMNCQPPKHTGRAAQIQTVFIALLFFPSFVGALSMVAFTVWSLQPSDQCGPFQGLKTPFHTIFNWTDSIQGPPETHWVWWIFENVLRSELFYYLISLIVLVITFFLWQITQGRKQLIKSLREQIVNGGKDKAFLLNKLQNIQRQRREIASYSPQPIRRSMRGSVRTVAQEFDQTTYYNPNWINTLPMDM-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *.: .:* :* . :.: * :. .:*::.* ::: *::***. * : :*:: :*: *:: * :: ** :* :.:* ::** : **:. : : :**.*** ***:********* **:******:***::**.** ***:. * .:. * ***::******.:**::** * ...* .:*******:***.* :. * :**::**:: *::**: *** :*: .***:*.:***:: :::**. :::*.*** * :.*:::.: :.::* :***::. :*:.. *.:*:*. :* * .:. . .:.****.*** *** ** :**:: :* *. ** ::*: : ***:**:*::****:**** *. . ***:::**.:****::**:*.*:. *:*****.:** * ***: *********:*******.****:*.****.:*:: ***:** *::** ** ***.:: **:*: *.** *******.*.*. :*:*:* *:** :****:** :*:*:.* *::. * ** **:.*:: * *:::::****:**:: ****:*** :*: *:***:* **** **::** ::* .:: . * **.:. . *.* : ... ", "identical_positions": 294, "similar_positions": 225, "identity": "28.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120411-9", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A2AVJ5-1", "uniprot_id": "PRR5L_MOUSE", "id": "A2AVJ5-1", "name": "Proline-rich protein 5-like", "aln": "MTRGLAPLLPIEFHKMGSFRRPRPRFMSSPVLSELPRFQAARQALQLSSNSAWNSVQTAVINVFKGGGLQSNELYALNESIRRLLKSELGSFITDYFQNQLLAKGLSFVEEKIKLCEGDNRIEVLAEVWDHFFTETLPTLQAIFYPVQGQELTIRQISLLGFRDLVLLKVKLGDVLLLAQSKLPSSVIQMLLILQSVHEPTGPSEGYLQLEELVKQVVSPFLSISGDRSCSGPTYSLARRHSRVRPKVTVLNYASLMTTVGRPLNEMVLTPLTEQEGEAYLEKCGSVRRHTVANAHSDIQLLAMATMMHSGLGEEAGGEDKHLLLPPSFPPPHRQCSSEPSILDSPDELELEDVASGSQEDSELNCASLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6MZQ0-1", "uniprot_id": "PRR5L_HUMAN", "id": "Q6MZQ0-1", "name": "Proline-rich protein 5-like", "aln": "MTRGFAPILPVEFHKMGSFRRPRPRFMSSPVLSDLPRFQAARQALQLSSSSAWNSVQTAVINVFKGGGLQSNELYALNENIRRLLKSELGSFITDYFQNQLLAKGLFFVEEKIKLCEGENRIEVLAEVWDHFFTETLPTLQAIFYPVQGQELTIRQISLLGFRDLVLLKVKLGDLLLLAQSKLPSSIVQMLLILQSVHEPTGPSESYLQLEELVKQVVSPFLGISGDRSFSGPTYTLARRHSRVRPKVTVLNYASPITAVSRPLNEMVLTPLTEQEGEAYLEKCGSVRRHTVANAHSDIQLLAMATMMHSGLGEEASSENKCLLLPPSFPPPHRQCSSEPNITDNPD--GLEEGARGSQEGSELNCASLS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WFB5-1", "uniprot_id": "X1WFB5_DANRE", "id": "X1WFB5-1", "name": "", "aln": "---------------MGSLRKPRPRFMSSPVLSDLARFHASSPTLQLSNASVWNSVQTAVIKVFEGGGLQPNELYTLNESIRWLLRTELGSFITEYFQDQLLNKGLTSILEQIQLHDDENRLQALSEMWVRFFTEILPTLQAIFYPVQGQELTVRQMALLGFRNMVLLKLSLEKVLQ--DSSCPSSITQMLLILQGIHEPNGPTQEYFLLERLVEMVISPYLSNYLKRSPSDSSSEGNR-------LVNTPHLAQPEIMVTHFAHESFLAPLIEHEGEAYLERTAGVRRHTVANVQSDIQLLTMNNRMHSEKVEVSG--TSRTTKTESKRTPKTPFCSEPAFFDSLP--SGMEIRRG-QSNAEMKCGLTS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:*:************:*.**:*: :****. *.*********:**:*****.****:***.** **::*******:***:*** *** : *:*:* :.:**::.*:*:* :**** *****************:**::*****::****:.* .:* :*. ***: *******.:***.**:: *: **.**: *:**:*. .** *..: * *.. : *. * : :* .*:** *:*******: ..********.:******:* . *** * :. . . * .*: .*** : *. : * *..:*::*. *", "identical_positions": 184, "similar_positions": 89, "identity": "49.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120419-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5U2X4-1", "uniprot_id": "DPEP3_RAT", "id": "Q5U2X4-1", "name": "Dipeptidase 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQPT-------------GPEGPRALS-------------------------------------------------------------LRPLGHRLSLLGVLLIIPSLWVTCNQTTPSLSSAPTSPGASSAMTTPG---------------------------IPNDTTTSGVTSD--PR---LREQALALMRDFPLVDGHNDLPLLLRELFQNKLQDVNLHN----------FTRGQTSLDRLRDGLVGAQFWSAYIPCQTQDRDAVRVALEQIDLIRRMCSAYP-ELELVTSADGLNSTQK---LACLIGLEGGHSLDTSLAVLRSFYELGVRYLTLT-FTCSTPWAESATKFRHHFYTNISG--LTSFGEKVVEEMNRIGMMIDLSHASDTLVKQTLEASRAPVIFSHSAARSVCD--NLLNVPDDILQLLKKNGGIVMVTLSMGVLQCS-LLANVSTVADHFDHIRTVIGSEFIGIGGSYDGSGRFPQGLEDVSTYPVLLEELLRRG-WGEQELQGVLRGNLLRVFRQVEQVRE--KSLGQSPVEVVFPERQQSSTCHSHLLPQSQ-----DAHLKVTKLPSSQVLQRA-----SKAPPCPLLGLVAAVTSPAFTLWLCCSGHR--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9DA79-1", "uniprot_id": "DPEP3_MOUSE", "id": "Q9DA79-1", "name": "Dipeptidase 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQPA-------------GLEGPRALG-------------------------------------------------------------LRPLGHRLSLLGVLLLVPSLWVTCTLTTPSPSSAPTTPEASNATTAPG---------------------------IPNDTATSGVTSD--PR---LREQALALMRDFPLVDGHNDLPLLLRELFQNQLQDVNLRN----------FTRGQTNLDRLRDGLVGAQFWSAYIPCQTQDRDAVRLALEQIDLIRRMCSAYP-ELELVTSADGLNNTQK---LACLIGVEGGHSLDTSLAVLRSFYELGVRYLTLT-FTCSTPWAESATKFRHHFYTNISG--LTSFGEKVVEEMNRLGMMIDLSHASDTLVKQTLEVSQAPVIFSHSAARSVCD--NLLNIPDDILQLLKKNGGIVMVTLSMGVLQCS-LFANVSTVADHFDHIRTVIGSEFIGIGGSYDGSGRFPQGLEDVSTYPVLIEELLSRG-WDERELQGVLRGNLLRVFRQVEQVRE--KSLGQSPVEVKFPERQQSNTCHSHLLPQPQEDQHQDTHLKVTKLPN--ILQRA-----SKAPPHPLPGLMATLTSLALILWLCCSGHRAV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4B8-1", "uniprot_id": "DPEP3_HUMAN", "id": "Q9H4B8-1", "name": "Dipeptidase 3", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQPT-------------GREGSRALS-------------------------------------------------------------RRYLRRLLLLL--LLLLLRQPVTRAETTPGAPRALSTLGSPSLFTTPG---------------------------VPSALTTPGLTTPGTPKTLDLRGRAQALMRSFPLVDGHNDLPQVLRQRYKNVLQDVNLRN----------FSHGQTSLDRLRDGLVGAQFWSASVSCQSQDQTAVRLALEQIDLIHRMCASYS-ELELVTSAEGLNSSQK---LACLIGVEGGHSLDSSLSVLRSFYVLGVRYLTLT-FTCSTPWAESSTKFRHHMYTNVSG--LTSFGEKVVEELNRLGMMIDLSYASDTLIRRVLEVSQAPVIFSHSAARAVCD--NLLNVPDDILQLLKKNGGIVMVTLSMGVLQCN-LLANVSTVADHFDHIRAVIGSEFIGIGGNYDGTGRFPQGLEDVSTYPVLIEELLSRS-WSEEELQGVLRGNLLRVFRQVEKVRE--ESRAQSPVEAEFPYGQLSTSCHSHLVPQNG---HQATHLEVTKQPTNRVPWRS-----SNASPYLVPGLVAAATIPTFTQWLC-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9H4A9-1", "uniprot_id": "DPEP2_HUMAN", "id": "Q9H4A9-1", "name": "Dipeptidase 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQPS-------------GLEGPGTFG-------------------------------------------------------------RWPL---LSLLLLLLL--LQPVTCAYTTPGPPRALTTLGAPRAHTMPG---------------------------TYAPSTTLSSPST--QG---LQEQARALMRDFPLVDGHNDLPLVLRQVYQKGLQDVNLRN----------FSYGQTSLDRLRDGLVGAQFWSAYVPCQTQDRDALRLTLEQIDLIRRMCASYS-ELELVTSAKALNDTQK---LACLIGVEGGHSLDNSLSILRTFYMLGVRYLTLT-HTCNTPWAESSAKGVHSFYNNISG--LTDFGEKVVAEMNRLGMMVDLSHVSDAVARRALEVSQAPVIFSHSAARGVCN--SARNVPDDILQLLKKNGGVVMVSLSMGVIQCN-PSANVSTVADHFDHIKAVIGSKFIGIGGDYDGAGKFPQGLEDVSTYPVLIEELLSRG-WSEEELQGVLRGNLLRVFRQVEKVQE--ENKWQSPLEDKFPDEQLSSSCHSDLSRLRQRQ-SLTSGQELTEIPIHWTAKLPAKWSVSESSPHMAPVLAVVATFPVLILWL--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8C255-1", "uniprot_id": "DPEP2_MOUSE", "id": "Q8C255-1", "name": "Dipeptidase 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSLT-------------GLKGHWVLG-------------------------------------------------------------HGLS---VFLLVLLLLGPSQPLIWTQTKPGFSGASTTSSIPRALTKPD---------------------------ISSIPTTPGNPNF--PD---LRDRARALMQEFPLIDGHNDMPLVLRQFYQNGLQDANLRN----------FTHGQTSLDRLKDGLVGAQFWSAYVPCQTQDRDALRLTLEQIDLIRRICASYS-ELELVTSVKALNSTQK---LACLIGVEGGHSLDNSLAVLRSFYLLGVRYLTLT-HTCNTPWAETSSKGVHAFYSSVTG--LTSFGEKVVAEMNRLGMMVDLSHVSDAAARRALEVSQAPVIFSHSAARAVCP--NARNLPDDLLQLLKKNGGIVMVTFSVGVLPCN-PLANVSTVADHFDHIRSVIGSEFIGIGGDYDGTKQFPQGLEDVSTYPVLIEELLRRG-WNEQELQGILRGNLLRVFRQVEQVRD--KSKWQSPLEDMIPEEQLDSACHSALR--PQKQ-HPEKNQ--PETPEYHILKF----SHSKSSPHIVPSLAIVATLLGLIV----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32TYD9-1", "uniprot_id": "A0AB32TYD9_DANRE", "id": "A0AB32TYD9-1", "name": "Dipeptidase", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MWIPY-------------KPPKTSFLSGP---------------------------------------------------------SFIFVFTKYILNLVDITKSEYEKSLCLKKVQSSQSQSTEGGDVSPRAFKL---------------------------RHNACKTHWHLKFPHRKTECEPLHVHEYITPVFFQTRHNDWALHLRKHDDNKLTKVNLYN----------YPQGATDITRLIAGHVGGQVFSAYVLCTAQDKDAVRLTLEQIDVIRRMCTEKP-ELELVTTSEGMKKSTK---IACLISVEGGHSIDSSLAALRMFYQLGVRSMSLT-HTCNTPWAKSSSSFYQHYQWVNNS--LTEFGKEVVHEMNRLGMLVDLSHSSWETARAVLKHTAAPVIFSHSSAYAVCN--NVRNVPDDLLLLLKRNGGLIMVNLYNNFIACSSNKANVSIVADHFDHIKRVIGAESIGIGADYDGAQGFPEGLEDVSKYPALIEELIARN-WTEQELAGVLRLNFLKVFEMVEKIRD--DMLDTSPSEVEIPFLEANNSCRAMLIHPTK----------VSKMVK------------NGNAPQTMPAGAFAWFILFLIQSI--------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VBG1-1", "uniprot_id": "Q9VBG1_DROME", "id": "Q9VBG1-1", "name": "Dipeptidase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKSR-------------KLPKGFVLCGLNCLTFVY-----------------------------------------------------FPLVLPILR------------------CSAGAASSASGGGSKTADD---------------------------------------------FDFRMQRVRNVLKEVPLIDGHNDLPWNIRKFLKNQLKDFHFGGDLRELAPWSSSAWSHTDLRRLKEGMVSAQFWSAYAPCSSQHLDAVQLTLEQIDLIRRLVQLYPHHMALVTTASGIEQTHRTGKIASLIGVEGGHAIGTSLSVLRMFYQLGARYLTLT-HTCNTPWADCCKVDEPGKYPHIGG--LSQFGKLVVKEMNRLGMIVDLSHVSVPTMLDALAASRAPLIFSHSSAHAICN--SSRNVPDHVLQRIAINGGLVMVAFYPHFVSCS-GQATLHDVVAHINHIREVAGIDHVGIGAGYDGVNLVPKGLEDVSKYPHLFAALLESDKWSEEDIAKLAGRNLIRVFKEVEAVRDQMELLRVAPIDQSIPAEDIMGRSYCRYQGPRT------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "X2JCU8-1", "uniprot_id": "X2JCU8_DROME", "id": "X2JCU8-1", "name": "Dipeptidase", "aln": "---------------------------------------------------------------------------------------------------MSSGEWDLRALKALEEEEQREFLALSQRNLFDPLPNPSPDVPSAKPSLTYAQLHPHLLKLPTIDECQLMAVKQQRSAALRFSRALSLSAHSLTSRTGSATAGGSGLGFGRKLKARL-VGAKSSGSLSPGRHSHSYSVSPVYTPPPMRRCATLHHTQPVRKVFKNLQQLQERKRQAAGSH---LQRIAGTGKTYWKYGANSTAASIVGQRARQNQQIEVEEPNGSDELNSETQEISEAETGSCSVPLPSKDTNEILRLMLSAASSAVTVTPTAAAIGNGNVAGATGGAPPMRRYQNASDVEEDETVAYGAFHQAAKSFERGALLRVGSLTAQESDNSKVNAISPSPQNSPARETQSTAVGGTGGRRVFKSCSFDWPGEAQQHLSPQPHQAANPVELLEQQGKDIRFRQRDHWDLEHAHFHHEALGHLTTSTTVIDD-------------ELEQHIKHCSCSCNHMGYGNSMDYQTTGFGGLPDVTEHSNIRRTLSRQNSISNSDSGGEIASIQKSKVNFGNPLAGGVVVGGDIVGLDAKSPTSLGSTTGAGATGKAKGKASRKANAGPDGGQKGRRGSWLVAITLVSAICLLAIAATLAYQHFLMAPSRNSHAQRLRIVRRILREVPLVDGHNNYAWNVRKYAHSSL-ELHLSHDVDHKSLWSRPAWAQTDMERLKQGLVSVQVWSAYVPCEAQGLDAVQLALEQIDIVRRLSDMYARETVLATSSQDIVDAHRRGLLASLIGVEGGHTIGSSLGVLRSFYSLGARYLSLT-HRCDVSWAGSSAS------PAEQG--LTPFGKAIVREMNRLGMMIDLSHSSDATARDVLQVTRAPVIFSHSAARQLCN--STRNVPDDILRLVAENGGLIMLSFDSEDVACG-RQARLQDVIEHIKYVRAIAGIQHIGLGAGYDGIELPPLGLEDVSKYPELLAALLEDHNWSEEDVAMLAGRNFLRIMETVETVRDYWKRAAIQPIEQTEPQP----KTQCTYMSS--------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VJ94-1", "uniprot_id": "Q9VJ94_DROME", "id": "Q9VJ94-1", "name": "Dipeptidase", "aln": "MTELRRTNGLHKQHSLRDRQVHPMLHALADHGCNLSSGGNSAASTTSSSTATATTALGGAGGLGGLGGLNGGVGITSQRSVEFDEHDIFYVSPSKRKGATSVGSSGNVVTFSNFVSEQRLTPSSSNRGSLKRSKGRSNQSLCSCDAGDEAQLDLQPNAARPLYEYSLERKRKTHTYSCEQNAQILMRLERERNRKLSLTGMETGLGIGLGVGLGMGSGGGTGGAGDPQSDTPSLSDVDVIPPVPPPPSMKRNGSMRSLRLLQHLQQQQQQQQQSSHNNNLAQLCSSDLLQECTKSALDECTATLLKCTTTSNHSSSNSNASNNCNIAASISHNNNNQVKPDLCQPPGHAHNHRHKLHGNATPTRTPTPTTTNPPPPPPPFAAHEEDEIFSPHSKKSDPSLCFLPGGNTSSKYNTIGPSSDYARHLAHYSRYLQKQHHQQQMAHFQQQRCRCFSQSLLSFPQQQQQQQQQQQHQQMQHAEQQQQHKAAQQPAIFHTSSMDWSLPINSRSFGNLVNIDGSGGTGGCRVPYQKMQSGNAGSGGAMANGCLGLAASSTFTLTSFDSDIGHGLKERESQTSLHHPHTLPHPHPHTHSHSHPHHYHAHVGGAAVSGGVGGSGSVTPQKHHQLHSSVTSIMPWKHRQCPSRGSSSSGTNSFRFDAAKHWLAVSSILLIIG-------------------AASVAVPLALRVAASAPFEERLRVAVQLLDQVPLIDGHNDLPWNIRKFLHNKLNDFNFDEDLRNVMPWGRSHWSHTDLTRLKKGRISAQFWAAYVPCEAQHRDAVQLTLEQIDVIKRLTDRYSPQLTTCTSAQDIIDAHKNQQLCSLTGVEGGHSLGGSLAVLRTLYAIGVRYMTLT-STCHTPWADSSYADAPTFNMKHGG--LTIFGKTIIREMNRLGMMVDLSHVSKGTMRDALEVSEAPVIFSHSSAYELCN--TSRNVQDDILQALAKNGGLVMVNFYSKFLSCS-DNSTVHDAVAHINHIKRVAGIDHVGLGAGYDGINYTPKGLEDVSSYPTLFAELLGGG-WTIDELTKLAGGNFLRVMQQVEKLRDDKKAAGVKPFEDH-PNFRTDDPYNCTSS----------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VPG0-1", "uniprot_id": "Q9VPG0_DROME", "id": "Q9VPG0-1", "name": "Dipeptidase", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNPVPSREFLEVH-------------PLHQHQPHCKQQC--------------------------------------------------------FVFTEIADIELPAEITKFGGGNEKIRCSNGGIPTYSSKKDSCSESSAERP--------------------------ERSRGRKILLGVGVVLVCIAMAGGIPLALQLRSSSLLEARLAFIRRLLTESPLIEGSWKPP-------STMSLNSSNLFEVRQNHIGAVLWPIAVPCGAQYLDAVQLTLEGIDRAKRITAATD-SMHIVESADEMEQTHIRGEVAVLMGISGGHALGTSTAVLRSIYLLGARFVSITSLECTTPWAAAAIRRPDYLVEENVTNSFNEFGQTMLFEMNRLGMLVEISMLSEAAMLAVLKTAKAPVLLTNATPLSMCNSSNIASIPDHVLSLLPENGGVILLNLER----CGDRTLGVREAITAINYVRKVAGVDHIGLGG-------------APKSYALLLAELARDRVWGNAAIKKLVGGNVMRILREIETLKN-----RLPLYEEWIPHESIESNSYCRYPES--------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0ABK0LWT1-1", "uniprot_id": "A0ABK0LWT1_RAT", "id": "A0ABK0LWT1-1", "name": "DPEP2 neighbor", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDRIFYINSNLSSVPCEGCYSTPVPPTAPSSPGYYHVLYKG--------------------------------------------------------------HAQAQMAWHGETYCLIGG--YRVYGDAPLPTPVKV----------EEEKPAPRRAPKRQRVQEESDQDLGCP-------SAKIPRLKLKHGGKG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . * .: : :: * :*. : :: . : .: * .: :** ", "identical_positions": 6, "similar_positions": 19, "identity": "0.52%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120420-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8IXH6-1", "uniprot_id": "T53I2_HUMAN", "id": "Q8IXH6-1", "name": "Tumor protein p53-inducible nuclear protein 2", "aln": "MFQRLSSLFFSTPSPPEDPDCPRAFVSEEDEVDGWLIIDLPDSYAAPPSPGAAPAPAGRPPPAPSLMDESWFVTPPACFTAEGPGLGPARLQSSPLEDLLIEHPSMSVYVTGSTIVLEPGSPSPLPDAALPDGDLSEGELTPARREPRAARH-AAPLPARAALLEKAGQVRRLQRARQRAERHALSAKAVQRQNRARESRPRR-SKNQSSFIYQPCQRQFNY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CFU8-1", "uniprot_id": "T53I2_MOUSE", "id": "Q8CFU8-1", "name": "Tumor protein p53-inducible nuclear protein 2", "aln": "MFQRFTSLFFNTPAPPEDSNCPGAFVSEEDEVDGWLIIDLQDSYTAPPDPGASPAPAGRPPPAPSLMDESWFVTPPACFTAEGPGLGPARLQSNPLEDLLIEHPSMSVYVTGSTIVLESGPPSPHPEAALPDQDLSDGELAPALREPRALHHAAAPMPARAVLLEKAGQVRRLQRARQRAERHTLSAKVLQRQNRARESRSRR-PKHQGSFIYQPCQRQFNY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F458-1", "uniprot_id": "E7F458_DANRE", "id": "E7F458-1", "name": "", "aln": "MFQRLTNLLFGSVNETTQEPTVPKPASPEVDEEGWLLVNAADGESS-------------------------------------------------------ETGELQFKLIGSLSNTEICAASLVSEASIAEPEVP---------VARSSGRVSQRLVSQAGALVKVTQMGRIQRAQARANRHSLGRNCIQRQNNIRQRLPQHFSRKHRMVLHQPGRCNFNH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****::.*:*.: . : .* * : :***::: *. :: * .:.. : ** * ..* .:*::.: ::. .*: : : : ::* * *. *: *:***: **:**:*. : :****. *: .:: .::: .::** : :**:", "identical_positions": 41, "similar_positions": 64, "identity": "18.47%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120423-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A6X3-1", "uniprot_id": "D4A6X3_RAT", "id": "D4A6X3-1", "name": "KN motif and ankyrin repeat domain-containing protein 4", "aln": "----------------------------------MEKMDGRQFLSPDLKAKDQSPQGDEEKEPPKSYPYSVET------------PYGFHLDLDFLKYVDDIEKGHTIKRIPIHRRAKQAK--------FSTLPR----------------------NFSLPNSGDRSHAAPPQQNWSPVVPRKISLGTQEQ------------SQSVPLGDLPQATVHGNELSYHRKALLAKDTRQVEAGSLEDA----GSGRPQLLRASSMPATLPQNQAPEVPNLTSGPS---------ALLVLPPLQDEGSVRDGTFDPAEGLMGFQAAAQSTDRAVEELEPAIPEPVWEGAEP-------------------------EEGDIKAASHLSQPAPSSSVQNVSVDLE---------------------------------------------------------------------------EVDIQHHTRTADLALSPGSSTPSPPP-----LPSPIPENELS------------------------LEEIELNISEIPPPPPIEVDVRSVGVRVTEESLGLVETATSSIS--SLKSQVLDLEDKLSGRTEELAQVRAALEQQEEETKAREQRIQELECTVAH--------------LEEKLSQEKASDALDRTDAMVNTD--------------PLRELIPRESQDKNIGVNLLSTPVPECWASRAEKNGFPWVQT------------NHKQSYPSPEEPALPPQLSLPRGPEQ------------------------------ILASSLCSCLSMELRIEEEVSEQERDPDGGAGSLSREAGGSPWSR-RESAPVIREEASSQLPGAERPGRPASSPQDATIGQYVKKIQELLHEQWNCLEHG--YPELASAIK-----QPASKLSSIQNQLLSSLNLLLSAYSAQAPEP--KESPVPPSSTPPP----PPEISPSTSLKSIMKKK-----DYGFRAGGNGTKKNLQFVGVNGG--------YETTSSEDTSGEDS--SPEDLSDSETEKKQDCSEP-REDRDMHLSCEAGQGVSKGTGNSGHMSEPRKGVSHMKAER---YKPSEEFLNACQALSQHLPEAG---ATNKQLLRQSLNTISQEWFRVSSRKLSSPEAVAACLLEVQPQSPHLLKLLVNLADRSGNTALHYSVSHSNFAIAKLLLDTGVCNVDHQNKAGYTAVMITPLASPKTKEDMAVVWKLLREGNVNIQATQGGQTALMLGVSHDREDMVQALLSCKADVNLQDHDGSSALMLACHQGNADLVRLLLAHADCNSNLTDKAGQTALSIVLNS----------PAHVEIAELLRAHSEQGRSLGLKELQKN-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6P9J5-1", "uniprot_id": "KANK4_MOUSE", "id": "Q6P9J5-1", "name": "KN motif and ankyrin repeat domain-containing protein 4", "aln": "----------------------------------MEKIDG----------KDQSSQGDEEKEPPKSYPYSVET------------PYGFHLDLDFLKYVDDIEKGHTIKRIPIHRRAKQAK--------FSTLPR----------------------NFSLPNSGDRTYAVPPQQNWSPVVPRKISLGTQEP------------SQPLPLGDLPQASVQGSELNYHRKALLAKDARQAEAGSLEDV----GSGRPQLLRASSMPATLLQNQVPEEPSLTSGPS---------TLLALPLLQDEGSVCDGAFDPAEGLMGFQASAQSVDRELGELEPAIPEQVWEGAEP-------------------------EEGDLKASSHLSQPGPSSAVQSVPMDLE---------------------------------------------------------------------------EVEIEHHMREAELVLTPGSATPSPPP-----LPSPILENDLS------------------------LDEIELSISEIPPPPPIEVDVRSIGIRVTEESLGLLETDTSSIS--SLKNQVLALEDKLSGRTEELARVRAALEQQEEETKAREQRIQELECTVAH--------------LEEKLSQERASEAPDRTDATVNTD--------------PLQELTPRESHDKNIGVNLLNTPDPECRAPRAEKNGFPWVQN------------NHKQSYPSPEEPVLPPQLSLPRGPEQ------------------------------ILASSLCSCLSMELRIEEEGSEQEGGQEEGAGGLSRAAGESSWST-RESAPVIREEATSELPGAERPGRPASSPQDATIGQYVKKIQELLHEQWNCLEHG--YPELASAIK-----QPASKLSSIQNQLLSSLNLLLSAYSAQAPEPEPKETPAPPPSTPPPPPPPPPEISPSTSLKSIMKKK-----DYGFRAGGNGTKKNLQFVGVNGG--------YETTSSEETSGEDS--SPEDLSDSETEKKQDCSES-REDRDLHPSCEAGQGVPEGTRNSGHTSDRGEEVSHLRAER---YKPSEEFLNACQTLSQHLPETG---DTTKQLLRQSLNTISQEWFRVSSRKLSSPEAVAAYLLEVQPHSPYLLKLLVNLADRSGNTALHYSVSHSNFAIVKLLLDTGVCNVDHQNKAGYTAVMITPLASAETKEDMAVVWKLLREGNVNIQATQGGQTALMLGVSHDREDMVQALLSCQADVNLQDNDGSSALMLACHQGNADLVRLLLAHPACNSSLTDKAGRTALSLVLNS----------PAHVEIAELLRAHSEPGRSLGPKELQKN-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5T7N3-1", "uniprot_id": "KANK4_HUMAN", "id": "Q5T7N3-1", "name": "KN motif and ankyrin repeat domain-containing protein 4", "aln": "----------------------------------MEKTDA----------KDQSSQGDEEKDPPKSHPYSVET------------PYGFHLDLDFLKYVDDIEKGNTIKRIPIHRRAKQAK--------FSTLPR----------------------NFSLPDSGARPPAAPPLQNWSPVVPREASLGTQEQ------------NQSPPLGNAPQASTSRSEVSYHRKALLAEATRQLEAAEPEDAELTFGSGRPQLLRASSMPATLLHSRASEEPGLSLGPP---------APPALPPLQGEGSVCDGTFEPAEGLAGFHSSSPRAS-------TRIPELVQEGAEP-------------------------PEGVVKVPNHLPLPGPPFSFQNVLVVLE---------------------------------------------------------------------------DKEDEHNAREAEVLFTPGSPTPSPPP-----LPSPIPENELL------------------------LEEIELNISEIPPPPPVEVDMRSIGIRVTEESLGLARVDPGSIS--SLKQQVSALEGELSGRTEELAQVRTALQQQEEEIKAREQRIRELEFTVAQ--------------LEGQFHQENAKDTQGQTDVMVNTD--------------PVHGLLTRESCDKGIEVNLLGSMESESWGHRGEENGLLWGPD------------GHKQGNQSPAERVLLPQLSLPQGPEQ------------------------------VLTSSVHSFLSTELRIEEAGTEQEGGPQGGT----RGAGGFLWGSDRKTPPAGREETSSNLPGKEHPGRPPSSPTDATIGQYVKKIQELLQEQWNCLEHG--YPELASAIK-----QPASKLSSIQSQLLSSLNLLLSAYSAQAHPP-----KEPPASSSSP----PVEISPSTSLKSIMKKK-----DYGFRAGGNGTKKNLQFVGVNGG--------YETTSSEETSGEDS--TPEDLSDSEAEKKCDGPDH-KHVKDAHLTCEAGQGIPEGTCHAAQESGPGEEVPHSKAER---YKPSEEFLNACRALSQHLPETG---TTTDQLLRQSLNTISQEWFRVSSRKSSSPAVVASYLHEVQPHSPHFLKLLVNLADHNGNTALHYSVSHSNFSIVKLLLETGVCNVDHQNKAGYTAVMITPLASAETNEDMAVVWKLLREGNVNIQATQGGQTALMLGVSHDREDMVQALLSCQADVNLQDHDGSSALMVACHHGNVDLVRLLLAHPACDSSLTDKAGRTALSIALKS----------PTHMEIAGLLRAHAEQGRSLGL-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BDE3-1", "uniprot_id": "A0A8M2BDE3_DANRE", "id": "A0A8M2BDE3-1", "name": "", "aln": "----------------------------------MDKKSAN----------GFATKASESGVQRKQLPYSVET------------PYGFHLDLDFLKYVDDIEKGNTIKRVHIQRKNRGPK--------YSTLPR----------------------NFSLPGHGARPLAKDTWANTSTLGSKPKSRVTEVQQLFEFRASDATGGSSSISGSSATSQSKISGSSYLPSPKVAEESQVQTSSQNEQSIG--LSVRPHLLRASSMPVNVPRRKGSDSTDEQSSQSQN------GSTEKLFRPADGGDRRGSIPQDRASLHQQITAALKRVRELEEQVRTIPELKAQICSLRTEREGLLQKILQHQSEQKRPLQLKEIEVLQADLQVSALPPSTSGKEDALFLSKNKVADHEIVHEVPSDRSTEQLPEKPHFEVQ--------------------------LNVQPDSKINKPVTDTESEKEQVPAPVSVPVILIDKAETPTDPDEEEELLQEPTLQEEASKSPSEQVKEQERSEILLEDKQPTLLEGIPASESECTSTQEVTMTVQRPSVIIIEENTTAQPAEQQLVSNLELEAKLKTLEESLSKASCELEKTNVLLREEMDKNRQKDERIQELTDQVKEQI------------LQGPIETEPQPEPVVKCDASVSTDSKSVLEKGISTEPQPIEDPKVTESQCSSTQTNIVEARDIEVLAQVTTAEKIVGVEVVMCDQSIETDVLDNLEGNNSLEVLEMLENTDSIKNKEQECDIKDSELSQITDTKVSENVAESDTEEYVMVESAMVETLASEIEVTEPTVQKTESAESLGIESTVTEKEREEGSSGLQTQQEPKETQGQDPHPQSQRASEATASPAAIGQVVNRIQGLFNEQWASLGSGGQDAKGESSQK-----PHSSKISSIQSHLRGSLSALSAFYSPVQKGG----------------------AARQSGLKSIMKKN-----DCPDKQGNGGAKKNLKFVGVNGG--------YESTSSEDSSGEENQDAVEEVESSEPEVEQGEEDSGAAQEEAAAAGEQSEGVQAEGTEGSEEPDVCQASMSPQEEQPVSELVDKNFMAACHFLKDRMAEVS---APNKE-MRQVLMMLYQEWFRVSSQKDSQAETVTLYLREVGFHTPTLLRYIVNLADGNGNMALHYSVSHSNFTVVKLLLDTGLCEVDHQNKAGYTAIMLAALTATENPEDMEVAQQLLRMGKINARASQSGQTALMLAVSHGRATMVQVLLDSGAEVNLQDRDGSTALMCACEHGHTEIAKILLERPDCDLTLTDKDGHTALSVAMK-----------ASHTEIIDLLNARSDPGPVTDSAAPL-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8DYE0-1", "uniprot_id": "A8DYE0_DROME", "id": "A8DYE0-1", "name": "", "aln": "MSVRPNNAGDMLLHNSVIGGYDESKFAEKITHLTPTEQEAVKRFWRSLVLRSQRAFIEENARPIASSANPAPAGITRSVRSCNCCPYGYHIDLDFVRYCEALALEKPSEEEQRRRDRRRSRKSMEFMLGFESLFGGDWQAESRVQGKLSETSHESEPDSPHPIGGGGSLHMSQSYTTTPCYRPRSSSVPRFTYGSIPPRSESPFGTASSTCSSLRGGVESDAGIYHQRHRPAISPPETRAFLHEALDEVCSDFERTLERTSVKRRKSPYGAGSLSMDRNNNKLSLSISNGHGALKELKSHRLGNSTWDRHFDVADSCIGGNQSPTGTPRPFLRSNTLPLRQRPSPAEVQYESYVQATVAAN---------AKSPVEQLESAKSPGAPPPPPPRRHHLLATTPTGKPTFKEDRPQENGSVSSSSLQSPVISETGQTTADAQALFQIREQMALSLRRLKDLEEQVKVIPDMELELNSLRSEKQKLLRRNEELMRSQRQTPSPPSPG--LKTASPVQFTPQRISPVSLESLGARMRSSSTSASPSPSVVRRDVSTQAVVRPPATRDVSVGHQPTTRNVGVQPSETVYSKEELDKKVEQALTNAQKQQLRKLISVGTQMYVPQRDQKDSGVQTTPERPKLKYHVGVTVKPATRENFTSCKPDVRHVGSSDDRLDDVLCEKCAVSKRSVACGPETPAEKVKPAPQMPGRSNTFSLGENETVSVVRKTIGCQTPVTLVLSSGSQTTTAVVRSTGAQVNPQQQHSGVQCATEQVSRQTDTKG-----------------------LQRLTRSQTKAEQVSESVPRPTTRHTASNTDKVEEAEPAKVRTSHSACNTEEVRKRDVGCGDIVKPHISIACAANYCDSCKEAIQDLARGFSKASPTATRTGGAVRRSTSADSRIPRPKHLSSPSPVRKEFMRQNTYTLATPSPTPSPQVERKARLSSLQEKPPSVSSFQASEPLPESQSFIRQPQKDSLDLSLLGEDELIVREEKRVSISWSRDASPAPLMTSSGTTKSESPEQEPAMSSSSDSSPPIDVQIAQGARKKSSTPLKSSQSEGSQVTVIEQPATKAQLHQLAQADSEPRKKTELSQSLKDALKIINDSLLKKLGAKPISSQSLKSAKATIQDHWFTNSSTGKSDPHQVEDYLDYFESLSIPLLEYCVNLSDSNGNTAMHYAVSHGNFDVVSILLDSKVCDVNQMNNAGYTSVMLVSLAKLKQPAHRTVVERLFKMADVNIRAKKHCQTALMLAVSHGNGDMVNMLLDAGADINIQDEDGSTALMCAAEHGRVDVIKHLLSHPECDSLVTDVDGSTAFKIAWQAGHRDVGLLIYVHEQMLRSKLPNRGDATRSSLISPPRHKRQPSQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. . . .*. . . .. : ***:*:****::* : : :. :. :* : .: :.:* : . * * . . :. * .. . . . . . * * . : * . . * *:* . . . . : * .. . : . :. . . .. :: *. . : : : : **: * . : . : . * . . .. . : * . :* . . : . : : : . . .. : * : . * . . . : . . : : .* : : . . : . .: . . . .: . :. : . : : : . . * . *: . *. *.::..: . . : *. . :*:::: * . :: : *.:. . ::.: .:.. :. : .. ..*.. . : . . .:* . . * .:.: * : :.: : : ..: ::. : :.** ** *.. * * . : :*. ***:* .** *:**:***.** :..:**:: :*:*:: *:****::*:..*: : . *. :*:: ..:* :*.: ******.***.. **: **.. *::*:**.***:*** *..:*..:: : ** :. *: :** * **:.:. : . : * :.: ", "identical_positions": 115, "similar_positions": 276, "identity": "8.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120424-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZMQ6-1", "uniprot_id": "D3ZMQ6_RAT", "id": "D3ZMQ6-1", "name": "", "aln": "MADYSGKSGLLPCESCDMVFRSRALLAKHTKRFCIG-------GLTPEVTLKTQPSVAMEQRGTKIMAQEQRRS-----------DQEATKSSLKRLTEETELLRLSLQKIGPWATDT-------------------SQTAGSPEERLRDLQGTRARRVEETEAQSRALKQRGEELKRRLHSVAGPKGGLPRPIVLERELRELREEASRTRGALQTLGARVQALQ-----PQPAHQQDAKRVVEFCCLPLRYNPETLAEEIRVLREVYVRGGGRDPEVLDKILQLQVEASALELRRSQNR--------KEKASAASEEALMVEAENRILEAEILALQKQK-VLSLSPWGSR---DLWRHLSRRSDNSLLPPPVAPPMPPVTSSTKVQDFHGTSKAIINGTMTRNLGLDLHF-LPASNVLGPAPYDPGAGLVIFYDFLRGLEASWIWVQLMTSLARDGQDTGGATALPPALCLPP--PSASGPIGNCAILASRQPVPRLPPSPLLSLICKLQAWQGVTWT------PQPKAWASLLLFDQSLRVLSGRWRLPLRVPP-TTSLSFAQMNEMPQVSVEGRDWLHPKIPMEYHFLCQAGQAELFLRLVNARDTDAQTLAEINPASAHEYQYPPMMSSSSSLESSFFTHSSGIADPPPPTEETFVSVEDKDEHLSPHQF--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CE13-1", "uniprot_id": "CCD17_MOUSE", "id": "Q8CE13-1", "name": "Coiled-coil domain-containing protein 17", "aln": "MADYSGESGLLSCESCDMVFRSWALLATHTKRFCIG-------RLTPEVTLKSQPSVAIK-RGTKIMAQEKSR------------DQEASTSALKRLTEET---------------------------------------AGSPGERLRVLQGTRARRMAETEAQSRALERRGEELKRRLHSVAGPKGGLPRPFDLERELRELKEEANRTRGALQTLGAHFQALQ-----LQPRKLQDTHRAVEFCYLPLRFNPETLAAEIRILREAYVHGGGRDPEVLDKILQLQVEASALELQRSQNR--------KEKLSAASEEVLTVEAENRLLEAEILALQKQK-VLSLSPWGSR---DLPGHLSR-CDNSLLPPLVAPPIPQLTSSTKAQNFHGTSKTILNGTMTRKMGLDLHFLLPASDVLGPAPYDPGAGLVIFYDFLRGLDTSWIWVQLMTSLARNGQDTGGTTALPPALCLPQ--PSAPGPMGNCAILASKQPVPRLPPSPLVSLICELQAWHGVTWA------PQPKAWASLLLFDQDLRVLRGRWRLPLRVYP-NTSLSLAQRNEIP----------------------QAGQAELFLRLVNARDTDAQTLAEINPANAHEYQYPPMVSSSS-VESSFFTHSSAFADPPPPTEEAFVSVKDKNEHLSPHQF--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96LX7-4", "uniprot_id": "CCD17_HUMAN", "id": "Q96LX7-4", "name": "Coiled-coil domain-containing protein 17", "aln": "MDSHSGEPALLPCGTCDMVFRSSALLATHTQRFCIG-------HPTQEMTFGAQASVATEPQRAAVVPQEHQGVP---QEPQGLPDQQASRSALKRLTEEVQWLRLSLQEMRPWITEVPRVFAGPWTRSEARPQSPMSEAVGSPSERLRALFRTRARRVAEMEAQSRALQLRGEELSRRLQVVACTRGGMSRLFGLEQEIRELQAEAGRTRGALEVLGARIQELQ-----AEPGNPLSSRREAELYSPVQKANPGTLAAEIRALREAYIRDGGRDPGVLGQIWQLQVEASALELQRSQTR--------RGRAGATSGELPVVEAENRRLEAEILALQMQRGRAPLGPQDLRLLGDASLQPKGRRDPPLLPPPVAPPLPPLP---------GFSEPQLPGTMTRNLGLDSHFLLPTSDMLGPAPYDPGAGLVIFYDFLRGLEASWIWVQLRTGLARDGRDTGRTTALPPALCLPP--PPAPGPMGNCAILASRQPVPRLPPSSSVSLVCELQVWQGLAWAR----APQPKAWVSLGLFDQDQRVLSGRWRLPLRALPLDPSLSLGQLNGIP----------------------QAGQAELFLRLVNARDAAVQTLAEINPASVHEYQYPPPVSSTSSLEASFLTPAVGFADPPPRTEEPLSGVKDRDEGLGPHHSSDLPPVSF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PZG6-1", "uniprot_id": "A0A8M1PZG6_DANRE", "id": "A0A8M1PZG6-1", "name": "", "aln": "----MDNLGELICRNCSMVFHSVGLLDKHKAKLCIGTDLREPAYLGRRQTEKAALHPTRARTPDLIILKEKRRDDQTEKEQDKAQDNGPHNTALNKLTEEFQKLRISFEQNLAGKHTEVS-----------------KEQCLVQQRNDEQRYKDHEQRLAEIRARNLQLEKDREEIEQRLAELAGRE----KTAHLEEVLQELRYQEQRNEEVLLQLSSHINTIKGPAPSEVPSNPPEEKKTQHVTFDLMSSVDGPLSAQIRALRLAYMQSGGSDPEVLAHMHDLQTEALTLEQTRPRADGRTKARRMKSPQRSLDPDILALEQENQKLEEEIFRIQQARERHKGENGSGVVDIQKDHIYQMESLQAEIAFLSGETEQDRERRQHHLQPPLSVFPESSMALTHPALDQTSLVTDSIEAFGPVQYDPAAGFMIFYDIIIGIEAALRSVRLLAGLYCNGQPLGQTIAMPPVQCQPAGSLLSTKIPGNYAILAAKQPVPSVQPSPDFSLVMEIQTLRGLDFYNHETEGFATFGWAKLELFDQHNQVHSGFWRLPFHFLPVQAALSSFQLNSMP----------------------QLSKMEVCLRIVNACDGDARSFAKMDPN-INLYKYFTVVTKSNSGTI-------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . * * .*.***:* .** .*. ::*** . * : : :: :*: *: . ::*::**** .. . : :*: * .*:. *: **:.:** :* . : **. ::**: : *.. .* *.::.: :: * : . :: .. .*: :** ** .*::.** ** ** :: :**.** :** *.: : : . : :* **: ** **: :* : . : . . :. . . . ::*: : : : : :**. ***.**::****:: *:::: *:* :.* :*: * : *:**. * * :. ** ****::**** : **. .**: ::*. :*: : . .*..* **** :* * ****:: * .:** * * :* * .: *: **:*** * .:::*:::* : *:* . ::.:. ", "identical_positions": 134, "similar_positions": 162, "identity": "19.65%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120426-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K097-1", "uniprot_id": "LFG2_MOUSE", "id": "Q8K097-1", "name": "Protein lifeguard 2", "aln": "MTQGKLSVANKAPGTEGQQHQANGEKKDAPAVPSAPPSYEEATSGEGLKAGTFPQGPTAVPLHPSWAYVDPSGSSGYEGGFPAGHHEHFTTFSWDDQKVRRLFIRKVYTILLVQLLVTLAVVALFTFCDVVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLILLTIFTLSMAYLTGMLSSYYNTTSVLLCLVITALVCLSVTIFSFQTKFDFTSCQGVLFVLLMTLFFSGLLLAVLLPFQYVPWLHAVYAVLGAGVFTLFLAFDTQLLMGNRRHSLSPEEYIFGALNIYLDIIYIFTFFLQLFGTNRE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BWQ8-1", "uniprot_id": "LFG2_HUMAN", "id": "Q9BWQ8-1", "name": "Protein lifeguard 2", "aln": "MTQGKLSVANKAPGTEGQQ-QVHGEKKEAPAVPSAPPSYEEATSGEGMKAGAFPPAPTAVPLHPSWAYVDPSSSSSYDNGFPTGDHELFTTFSWDDQKVRRVFVRKVYTILLIQLLVTLAVVALFTFCDPVKDYVQANPGWYWASYAVFFATYLTLACCSGPRRHFPWNLILLTVFTLSMAYLTGMLSSYYNTTSVLLCLGITALVCLSVTVFSFQTKFDFTSCQGVLFVLLMTLFFSGLILAILLPFQYVPWLHAVYAALGAGVFTLFLALDTQLLMGNRRHSLSPEEYIFGALNIYLDIIYIFTFFLQLFGTNRE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A140LGC1-1", "uniprot_id": "A0A140LGC1_DANRE", "id": "A0A140LGC1-1", "name": "Protein lifeguard 2", "aln": "MTQKKVAPADQA---------VEGSK---------PPSYEEANAG-----------------CPGYYYGDGG-------------------FTWDDASVRRIFIRKVYSILMLQLFSTVAVIALFTFHAPVRMYIQTHPILYSASNLLFLITYISLACCGDLRRQFPWNLILLTVFTLSMACMLGFISSFYNTKAVVLCIGITAVVCLCVTLFSFQSKIDITSYQGLLFILCMVMFFCAIVMGFVVPFGYVPWLHAVYSSIGAVVFTMFLAFDTQLLMGNKQYTLSPEEYVFATLSLYLDIVYLFTFLLQMFGQGRD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** *:: *::* ..*.* *******.:* *.: * * . *:*** .***:*:****:**::**: *:**:***** *: *:*::* * ** :*: **::****.. **:*********:****** : *::**:***.:*:**: ***:***.**:****:*:*:** **:**:* *.:**..:::..::** *********: :** ***:***:********::::******:*.:*.:****:*:***:**:** .*:", "identical_positions": 155, "similar_positions": 80, "identity": "48.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120427-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P69060-1", "uniprot_id": "NEUA_RAT", "id": "P69060-1", "name": "N-acylneuraminate cytidylyltransferase", "aln": "MDALEKGAATSGPAPRGRPSRGRPPKLQR-SRG-AGRGLEKPPHLAALVLARGGSKGIPLKNIKRLAGVPLIGWVLRAALDAGVFQSVWVSTDHDEIENVAKQFGAQVHRRSSETSKDSSTSLDAIVEFLNYHNEVDIVGNIQATSPCLHPTDLQKVAEMIREEGYDSVFSVVRRHQFRWSEIQKGVREVTEPLNLNPAKRPRRQDWDGELYENGSFYFAKRHLIEMGYLQGGKMAYYEMRAEHSVDIDVDIDWPIAEQRVLRFGYFGKEKLKEIKLLVCNIDGCLTNGHIYVSGDQKEIISYDVKDAIGISLLKKSGIEVRLIS--ERACSKQTLS--ALKLDCKTEVSVSDKLATVDEWRKEMGLCWKEVAYLGNEVSDEECLKRVGLSAVPADACSRAQKAVGYICKCSGGRGAIREFAEHIFLLLEKVNNSCQK--------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q99KK2-1", "uniprot_id": "NEUA_MOUSE", "id": "Q99KK2-1", "name": "N-acylneuraminate cytidylyltransferase", "aln": "MDALEKGAVTSGPAPRGRPSRGRPPKLQR-SRG-AGRGLEKPPHLAALVLARGGSKGIPLKNIKRLAGVPLIGWVLRAALDAGVFQSVWVSTDHDEIENVAKQFGAQVHRRSSETSKDSSTSLDAIVEFLNYHNEVDIVGNIQATSPCLHPTDLQKVAEMIREEGYDSVFSVVRRHQFRWSEIQKGVREVTEPLNLNPAKRPRRQDWDGELYENGSFYFAKRHLIEMGYLQGGKMAYYEMRAEHSVDIDVDIDWPIAEQRVLRFGYFGKEKLKEIKLLVCNIDGCLTNGHIYVSGDQKEIISYDVKDAIGISLLKKSGIEVRLIS--ERACSKQTLS--ALKLDCKTEVSVSDKLATVDEWRKEMGLCWKEVAYLGNEVSDEECLKRVGLSAVPADACSGAQKAVGYICKCSGGRGAIREFAEHIFLLIEKVNNSCQK--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFW8-1", "uniprot_id": "NEUA_HUMAN", "id": "Q8NFW8-1", "name": "N-acylneuraminate cytidylyltransferase", "aln": "MDSVEKGAATSVSNPRGRPSRGRPPKLQRNSRGGQGRGVEKPPHLAALILARGGSKGIPLKNIKHLAGVPLIGWVLRAALDSGAFQSVWVSTDHDEIENVAKQFGAQVHRRSSEVSKDSSTSLDAIIEFLNYHNEVDIVGNIQATSPCLHPTDLQKVAEMIREEGYDSVFSVVRRHQFRWSEIQKGVREVTEPLNLNPAKRPRRQDWDGELYENGSFYFAKRHLIEMGYLQGGKMAYYEMRAEHSVDIDVDIDWPIAEQRVLRYGYFGKEKLKEIKLLVCNIDGCLTNGHIYVSGDQKEIISYDVKDAIGISLLKKSGIEVRLIS--ERACSKQTLS--SLKLDCKMEVSVSDKLAVVDEWRKEMGLCWKEVAYLGNEVSDEECLKRVGLSGAPADACSTAQKAVGYICKCNGGRGAIREFAEHICLLMEKVNNSCQK--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "H9BFW7-1", "uniprot_id": "NEUAB_DANRE", "id": "H9BFW7-1", "name": "N-acylneuraminate cytidylyltransferase B", "aln": "---MEGGRCAQVSSVPASPSSG-----HR--------------HRAALILARGGSKGIPLKNIKNLAGVPLIGWVLRAALDS-DVDSVWVSTDHDEIERVAKLWGAKVHRRSPEVSKDSSSSLETIQEFIRLRPEVDVICHIQATSPCLHPHHINEALQKITHQGFSYVLSVVRRHQFRWEELQENEDRNPKSFNINVAQRPRRQDWPGELYENGSFYFSTRKAWESGLTELGRIAYYEMPPEFSVDIDVDIDWPVAEQRVLRFGYFGREENAAVRLFLCKVSGCLTNGQIYMSVSGEDLVTINARDVAGIQMLQKENIEVILISSVNEPLSRGVLEKVSQRAGCGLSFTEQRNALEMQKLMDKRKLHWDQVAFMGSESEDVEIMSQAGLNGVPSDAPVAELIAAKYTCQRAGGHGAVREFAEYILSMKRKSSREENHERIDKHNF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IQV0-1", "uniprot_id": "Q8IQV0_DROME", "id": "Q8IQV0-1", "name": "", "aln": "--MIKLKPATFLILLVFLFETGCTENCLS-------------NDIHALILARGGSKGIKLKNLAEIGGSSLLARTIMTIKNSTCFRHIWVSTDDKRIAIEAQKYGAIIHHRPEKFARDDTPSLHAISEFLDVHRSIHDFALFQCTSVFLKTKYIQEAVRKFES--HDCVFAAKRSHYLRWKVVDG----ELMPAEFDLSARPRRQDWQGDIVETGMFYFSRRKLVDSGLLQNNRCSVVEIDAKDSLEIDSSHDLTLAKY-------------------------------ILSSETKTEL--------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: : . * . **:********* ***: .:.* .*:. .: : :: . :*****...* *: :** :*:*. : ::*.:.**.:* **: : .:. . :*.** *:. :::. . : .. *::. * * :**. :: . ::: : ******* *:: *.* ***: *: : * : .: : *: .: *::** . * .:*: * * :: ", "identical_positions": 66, "similar_positions": 87, "identity": "14.8%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120502-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A3FIN4-1", "uniprot_id": "AT8B5_MOUSE", "id": "A3FIN4-1", "name": "Phospholipid-transporting ATPase FetA", "aln": "MKYVKAFVSEISWDCSWYCSAMQERRNEDRQKEEEERILQANNRRFNSLFEYPDNSIKTSKYGFFNFLPMNLFEQFQRLANAYFLILLFLQLVPQISSLAWYTTVIPLIVVLSITGVKDAIDDVKRHRSDQQINNRSVSILVNGRVEEIKWRNVQVGDIIKLENNHPVTADMLLLSSSEPYGLTYIETADLDGETNLKVKQAISVTSAMEDNLELLSSFNGEVRCDPPNNKLDKFSGTLSYLGNTYLLNHERLLLRGCVIRNTDWCYGLVVYTGQDTKLMQNSGRSTFKRTHIDHLMNVLVVWIFMFLGGMCFLLSIGHGIWENSRGYYFQAFLPWKHYITSSATSSALIFWSYFIVLNTMVPISLYVSVEIIRLGNSYYINWDRKMFYAPKNMPAQARTTTLNEELGQVQYVFSDKTGTLTENVMIFNKCSINGKTYGYSYDDNGEYVPKSPK-DKVDFSYNHLADPKFSFYDKTLVEAVKSEDPLVYLFFLCLSLCHTVMSEEKVEGELVYQAQSPDEGALVTATRNFGFVFCSRTPETITVIEMGKIRVYRLLAILDFSNERKRMSVIVRTPEDRVMLFCKGADTIIYELLHPSCASLSEVTMDHLDDFASEGLRTLMVAYRELDKAYFQTWIKKHGEAWLTLENRERKLALVYEEIERDLMLLGATAIEDKLQRGVPETIVTLSKAKIKIWVLTGDKQETAVNIAYSCRIFKDEMDGVFMVEGTDRETVLEELRTARKKMKPESLLESDPINMYLARKPKMPFKSLDEVANGNYGLVISGYSLAYALEGSLEFELLRTACMCKGVVCCRMTPLQKAQVVDLVKRYKKVVTLAIGDGANDISMIKAAHIGVGISNQEGMQATLSSDFSFCQFHFLQRLLLVHGRLSYNRMCKFLSYFFYKNFAFTLVHFWYAFFNGFSAQTVYDIWFITFYNLIYTSLPVLGLSLFEKDVNETWSLCYPELYEPGQHNLYFNKKEFVKCLLHGIYNSFVLFFVPMGTVFNSERNDGKDISDFQSFSLLVQTTLIGVMTMQIALRTTSWTMINHTFTWGSLGLYFCILILLCSDGLCLRYPSIFNFLGVARNSLSQPQIWLCLILSTILCMIPLIGYNFLRPLLWPINADKVLNRIHFCLKHPIPTQVQTKIKHPSLRRSAYAFSHKQGFGALITSGKTLKSSALAKSKRFL------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2LAJ5-1", "uniprot_id": "A0A0G2LAJ5_DANRE", "id": "A0A0G2LAJ5-1", "name": "Phospholipid-transporting ATPase", "aln": "--------------MGSLLSACG--INVKKKKVEEERRLRANDREFNLSFKYANNAIKTSKYNVFTFLPLNLFEQFQRLANAYFVFLLILQLIPQISSLSWFTTVVPLLLVLSITLAKDLSDDITRHKNDKQVNNRKVEVLIDGELKTERWMNVQVGDIVKLENNEFVTADLLLLSSSEPLNLIYIETAELDGETNLKVKQALTLTGELCNDIQRLAAFKGEVRCEPPNNRLDKFTGTLVVGGETFALDNERILLRGCTLRNTEWCFGLVLFGGPDTKLMQNSGKSIFKRTSIDHLMNVLVLFIFGFLAFMCTILSIGNAIWEYQEGNSFIVFLPRADGAN-ASLSAFLTFWSYVIILNTVVPISLYVSVEILRLGNSYFIDWDRKMYHVKSDTPAQARTTTLNEELGQIKYIFSDKTGTLTQNIMTFNRCSINGKSYGEVVDFAGQRVEVTEKTEKVDFSWNLLADPKFFFHDHKLVEAVKLGSPEVHAFFRLLALCHTVMPEEKTQGDLFYQAQSPDEGALVTAARNFGFVFRARTPETISVVEMGIETTYELLAVLDFNNVRKRMSVIVRNPEGKLMLYCKGADTIIYERLHPSCSKVMEVTTEHLNEYAGEGLRTLALAYKDLDEDKFAEWRRRHHEASIALEDREEKLDAIYEEIEKDLILIGASAVEDKLQDGVPQTIEQLAKADIKIWVLTGDKQETAENIGYSCNMLREEMTEIFIVAANTAEEVREELVNARKKMSPESGDEPPMEKSRFLGKKSQVVE--DEKVDGEYGLVINGHSLAFALQKDMQVELLRTACMCQTVICCRVTPLQKAQVVELVKKHKKAVTLAIGDGANDVSMIKTAHIGVGISGQEGMQAVLSSDFSFAQFRYLQRLLLVHGRWSYLRMCTFLRYFFYKNFTFTFVHFWYAFFCGFSAQTVYDEWYITLYNLVYTALPVLGISLFDQDVNDRWSFQYPQLYAPGQMNQYFSKMAFAKILLHSCYSSLILFFVPWAAMWDTVRDDGKDIADYQSFALLAQTCLLIAVSVQLGLDTYYWTAVNHFFLWGSLSVYFAVTFTMYSNGMYLIFTSSFPFIGTARNSLNQPNVWLTIFLTTILCVLPVVAKRFLFIQFKPTINDKVRHKVKQAKAEPPPPPQRFPRRRISTRRSGYAFSHARGYGDLVTSGRFLRIPVKSRPALFSKNESPVADSTPQTYISIFEETQNP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ** * .::* **** *:**:*.** *:*.:*:******..*.***:**************::**:***:******:*:***:**::***** .** **:.**:.*:*:***.*.:*::*.:: :* *******:*****. ****:******** .* *****:************:::*. : :::: *::*:*****:****:****:*** *:*: *::**:*****.:***:**:***:: * *********:* **** *********::** **. ** :****:.*** ..* * .*** . . :: *: * ****.*:***:***********:******:*:*****::. .: ***************::*:*********:*:* **:******:** * *: * : * :*****:* ****** *:*:.****** .* *: ** *:******.***.:*:*.**************:******* :******:*:*** .*.***:***.* *********.**.::**:********** *****:.: *** :**:::*.****** :**::**: * * ::* ** ::**:**.** :*****:**:*:**:*:***** ***:** *:**.************** **.***.::::** :*:* .. * * *** .*****.*** *. : : * . .: ** .:*:*****.*:***:**: .::.*********: *:***:*********:***::**.***********:****:********.******.*******.**::********** ** ***.** *******:**:******** ********* *:**:***:**:*****:***::***: **: **:** *** * **.* *.* ***. *.*::***** .::::: *:*****:*:***:**.** *: .:::*:.* * ** :** * ****.:**.: : : *:*: * :.* * *:*.*****.**::** ::*:****::*::. .** : * *** :::: . .* *. : :: * ***.***** :*:* *:***: *: .. ::. * ", "identical_positions": 707, "similar_positions": 286, "identity": "58.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120502-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62769-1", "uniprot_id": "UN13B_RAT", "id": "Q62769-1", "name": "Protein unc-13 homolog B", "aln": "---MSLLCVR---VKRAKFQGSPDKFNTYVTLKVQN-VKSTTVAVRGDQPSWEQDFMFEISRLDLGLSVEVWN----------KGLIWDTMVGTVWIALKTIRQSDEEGPGEWSTLEAETLMKNDEICGTKNP------------------------TPHKILLGTRFELPF---DIPEEEARYWTYKLEQINALADDNEYSSQEES-----QRKLLPTAAAQCRHWTYLGWGE----HQTFEDPDSAVDDRDSDYRSETSNSAPPPYHTTTQPNASAHQFPMP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPLPQQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LFLQGSSRDS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNDSMQSYDLDYP----------------------------------------------ERR---------------------------------------------------------ALSPTSSSRYG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSCNVSRGS-------------SLLSELDQYHEQDDDGRERDS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IHS---SHSYG----------------------------------------------SLSRDGQAGLGEQEK---------ALEVACE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SQKEKTGESKE-RDDATVCPPS--------------------------------------------DLMLHKDLTLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQES-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FPEEKASS-------------------------------------------------------------------------------------------------------------------------PFTQARAHWFRAVTKVRLQLQEISD--DGDPSLPQWLPEGPAGGLYG---------------IDSMPDLR-RKKPLPLVSDLAMSLVQSRK--AGITSAMATRTSLKDEDLKSHVYKKTLQALIYPISCTTPHNFEVWSATTPTYCYECEGLLWGLARQGMRCSECGVKCHEKCQDLLNADCLQRAAEKSSKHGAEDRTQNIIMAMKDRMKIRERNKPEIFEVIRDVFTVSKVAHVQQMKTVKQSVLDGTSKWSAKITITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIFGNLNPVWEEKFHFECHNSSDRIKVRVWDEDDDIKSRVKQRLKRESDDFLGQTIIEVRTLSGEMDVWYNLEKRTDKSAVSGAIRLQINVEIKGEEKVAPYHVQYTCLHENLFHYLTDIQGSGGVWIPDARGDDAWKVYFDETAQEIVDEFAMRYGIESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYAHTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHDLYSHQYQLQ------EQPLEEPGPSIRNLDFWPKLITLIVSIIEEDKNSYTPVLNQFPQELNVGKVSAEVMWHLFAQDMKYALEEHEKDRLCKSADYMNLHFKVKWLHNEYVRELPALQGQVPEYPAWFEQFVLQWLDENEDVSLEFLRGGLERDKRDGFQQTSEHALFSCSVVDVFTQLNQSFEIIRKLECPDPSILAHYMRRFAKTIGKVLIQYADILSKNFPAYCTKERLPCILMNNMQQLRVQLEKMFEAMGGK-----------------------------------ELDSEAADSLKELQVKLNTVLDELSMVFGNSFQVRIDECVRQMADILGQVRGTGNASPNA-----RASVAQDADSVLRPLMDFLDGNLTLFATVCEKTVLKRVLKELWRVVMNTMERVIVLPPLID-QTGTQLILTAAKELSQLSKLKD-----------------------HMVREETRNLTPKQCAVLDLALDTVKQYFHAGGNGLKKTFLEKSPDLQSLRYALSLYTQTTDTLIKTFVRSQTAQVHDGKGIRFTANEDIRPEKGAGVDDPVGEVSIQVDLFTHPGTGEHKVTVKVVAANDLKWQT-AGMFRPFVEVTMVGPHQSDKKRKFTTKSKSNSWTPKYNETFHFLLGNEEGPEAYELQICVKDYCFAREDRVIGLAVMPLRDVAAKGSCACWCPLGRKIHMDETGMTILRILSQRSNDEVAREFVKLKSESRSIEEGS-----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9Z1N9-1", "uniprot_id": "UN13B_MOUSE", "id": "Q9Z1N9-1", "name": "Protein unc-13 homolog B", "aln": "---MSLLCVR---VKRAKFQGSPDKFNTYVTLKVQN-VKSTTVAVRGDQPSWEQDFMFEISRLDLGLSVEVWN----------KGLIWDTMVGTVWIALKTIRQSDEEGPGEWSTLEAETLMKDDEICGTKNP------------------------TPHKILLDTRFELPF---DIPEEEARYWTYKLEQINALADDNEYSSQEES-----QRKPLPTAAAQCCHWTYLGWGE----HQTFEDPDSAVDDRDSDYRSETSNSAPPPYHTTTQPNASVHQFPVP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VRLPQQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LFLQGSSHDS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNDSMQSYDLDYP----------------------------------------------ERR---------------------------------------------------------ALSPTSSSRYG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSCNVSQGS-------------SLLSELDQYHEQDDDGRERDS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IHS---SHSYG----------------------------------------------SLSKDGQAGLGEQEK---------ALEVTCE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEKEKTGESKEMRDDATIHPPS--------------------------------------------DLVLHKDHVLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQES-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LPEETASS-------------------------------------------------------------------------------------------------------------------------PFTQARAHWFRAVTKVRLQLQEISD--DGDPSLPQWLPEGPAGGLYG---------------IDSMPDLR-RKKPLPLVSDL--SLVQSRK--AGITSAMATRTSLKDEELKSHVYKKTLQALIYPISCTTPHNFEVWSATTPTYCYECEGLLWGLARQGMRCSECGVKCHEKCQDLLNADCLQRAAEKSSKHGAEDRTQNIIMAMKDRMKIRERNKPEIFEVIRDVFTVSKVAHVQQMKTVKQSVLDGTSKWSAKITITVVCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIFGNLNPVWEEKFHFECHNSSDRIKVRVWDEDDDIKSRVKQRLKRESDDFLGQTIIEVRTLSGEMDVWYNLEKRTDKSAVSGAIRLQISVEIKGEEKVAPYHVQYTCLHENLFHYLTDIQGSGGVWIPEARGDDAWKVYFDETAQEIVDEFAMRYGIESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYAHTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHDLYSHQYQLQ------EQPLEEPGPSIRNLDFWPKLITLIVSIIEEDKNSYTPVLSQFPQELNVGKVSAEVMWHLFAQDMKYALEEHEKDRLCKSADYMNLHFKVKWLHNEYVRDLPALQGQVPEYPAWFEQFVLQWLDENEDVSLEFLRGALERDKKDGFQQTSEHALFSCSVVDVFTQLNQSFEIIRKLECPDPNILAHYMRRFAKTIGKVLMQYADILSKNFPAYCTKERLPCILMNNMQQLRVQLEKMFEAMGGK-----------------------------------ELDSEAADSLKELQVKLNTVLDELSMVFGNSFQVRIDECVRQMADILGQVRGTGNASPNA-----RASVAQDADSVLRPLMDFLDGNLTLFATVCEKTVLKRVLKELWRVVMNTMERVIVLPPLTD-QTGTQLILTAAKELSQLSKLKD-----------------------HMVREETRNLTPKQCAVLDLALDTIKQYFHAGGNGLKKTFLEKSPDLQSLRYALSLYTQTTDTLIKTFVRSQTAQ-------------------GAGVDDPVGEVSIQVDLFTHPGTGEHKVTVKVVAANDLKWQT-AGMFRPFVEVTMVGPHQSDKKRKFTTKSKSNNWTPKYNETFHFLLGNEEGPEAYELQICVKDYCFAREDRVIGLAVMPLRDVAAKGSCACWCPLGRKIHMDETGMTILRILSQRSNDEVAREFVKLKSESRSTEEGS-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32TYW3-1", "uniprot_id": "A0AB32TYW3_DANRE", "id": "A0AB32TYW3-1", "name": "", "aln": "---MSLLCVR---VKKAKLQGPLDKFNAYVTLKVQN-VKSTTITVRGDQPCWEQDFMFEISRLDLGLIVEVWN----------KGLIWDTMLGTAWIPLKNICHSDEEGAGEWIFLDSEVLMKADEIYGTKNP------------------------TPHRVLLDTRFELPF---EIPEDEARYWTGKLERINAMGIHDEFPLQDEV-----VGRPLPCAASQCCN--YFGWAD----SQTLDDLDSAVEDRDSDYRSETSSSLPPRYHTTAQPNSSLHQYPMGPRFQQHMDSCADSLHSFEFDYRDHRASRAPNQKGRIRIVPVDSGMGVEDWEVKYKQGKSTLSEFLDREEQAWIEDQDRQSDVVHKEKDYHDPIIKQLLPIKNKNSVLNAAYPEGYATIDRRRKKKIRDPGGLEHAGAEHFPPDLAFLRQKRTELVLRQVKEMEEADENMTPCLKPYKNGLLYKTRMWAKNKLENTLENYVAYQEEEAARLREDVEFDSEGSDELHYSICSEEELEEMTSLAKALRGEEKKNNSHHGYFSTYGGQTERLQGYREKKNGKGKIGGWAPEVMLSPVEEPSDEYVDPMDELQCLVETVSEYLAEKEEEISKYGSLPKSNKSRLSSQGSARTESVGDEQGIISKEVKEKPIDAKESNLSGASDHGVSGVKNAMSSLFSSLTDKVVSGSKQAGSKSVEQSETPHNASSGISKLFSFMPKSTSPTPVAVVSPTDRKFSMSPVLPFQPSDAKLQEADQSIHSMENELTKYGGVKAHRESLSSVNSMLDAKQNKPGDPPTVLNGKTKLSKMSDAYQDNDSKKFKILKNTCNEINYKKTLTEPVPQKATEESGFFNPFRKSLSSLISPGPPVPPQSQTHTVFPVFRSAEDIRVEKLPDESSLKKQTFVSSDNVSVPQPQKSDGGLFSGLFKFASGEDSGASKSMPQITKTDQIPAVTKRVAGAIPASLPDNAKLTTPSNKEPPDTTSKGNTETGWFSSLFKMAPTEDLQPVTPPIHRPNIQSTLPPPGSNQTGHRMQHPNPTSAKEQMQVKHQQPGPTQVPNITEQNASQHERQGLFSGLFKSVASDNASSAQAFPNQPQQGGLLSGIMKFASTGDMATGAHVNQQRSQSAQILNQQNQPHTQTSASIPPLSGRLTITSTEISHREPQQFSQQETKSQQGSILSGLFRFASTEKPLDTQTTMPQEQQKSPSISYFQDSVQHKVEGQSRIQTQQSNFPKQQSERLQKGILDGHKQSVSHQGHSQQDGLLSGLFKFASSDVSVSQSAQQVQASNTQSSVLQSKTNVIEQSHSSQNNSSNQKHQSDGLLFLKVSSNESQELPVTQEKKEHASLPQQVATKQSSRVGRQETSAQPGILSGFFNKLTSSSEDVSLNIQNSVKQNQDKPQIPVEIHTQQGQSKRRLPQIPSQIQDTDQQPSTQQRFLYGIFSRNPTDVSTVKTEGVAMEGLQMKVSSTGLLRDNVANLNYVSNICGTESLDLRTPASYARSQQKCAAYTSHSTGNIPLLYSSQNFMLSSQIRTTSYSTENLPLCHPSQAVMSQECFRQSYPSFHCKPEQYGFQEISPSYALQPSPSDEHSWIQQSILWQQLNDQSLGIVPDGHEITPINEVHTSSQYLNDINMDINQQYSHTKPWMKFHSYNGSKNQSDYSTDVPNSLVRPRAWNSQNDLDVINNQEFEGVLNLSMKNNAKLSRWHSFSAESCYSLNSISYHEGYYEETPPHLSYSANGQYVYHGTSDICTQPGNSGSHVNVATSPNHWNYSSASNSDMEEHVYLEESEWYQQWLSLLDQGMWWPADDGDCGYFVYTDYEYIYALLTDESGQYVYACAPEQEWASTVDIYPSAWLYNEVVKVCGFKIPLYNEDELLWLPSQGQSEAELLTAPLDLSAAYKKGNQIMNLNLERFSQMFADSMLNQRQQALDFSSYRFNKVRMDTNHQLPHNYGYCDPSQEAVDLSFHGTNYNNVNLDSREIKELLSYKVSVSFGATQTTTSPTTGVYSCYQPQQRRRSSSGVQIKHIDDVSEEEWRKRVQPGEEQPNRSIKKISSILSSIVGKSSNSESSRNTAVSKSPSAKDGSFSGQNQSRSHKASETRLADQQAKSFISTGFQSLKSKIVKDDVCGTTQPDNTNQLSSKQIPTTPRVSVTSSAQPTASTPSQGACTLSSSQKPKLARQATLSQQSSLPPTSIVSTTLREQSSLTIKSASLDVSLPAETQGGKTSEQSSGFLNFFKTAVGIEEVKSEPSKSAHPVSRQADKVGTASDGMKDSTTNQDTTGTSKLFGSIGDFFNIESPSHTISKTNLQHSASTMTVPKGIQKQQTAENTFAKGGESEFPSLSQSIQGRSVSSSQIHSADANRLPTPGRSQTMPPTGETKPEAKQSGGLFGFSVGDIFSGTTASKDESKGLLSIFSGSSQQQAPSLSASTSLQGSISNSSAKEPLGKNILSLFGGSSIQQTSPQFGSTHQPCPPEAVPPKEYLGMNISSVFSGTSTQQPSTHVSSCNQKQTSTVHPKESPAMGLLSLISGSSTQQTSSESDQPKDTPMAGLLSTFSGPQQASSELGSGTDPPKDTPIKGLLSMFSGPQQTSLRSGSDPPKDTPVTGMLSMFSGPQQTAPRSGADPPKDTPITGLPSMFSGPQQTAPRSGADPPKDTTVTGLLSMFSSPQQTSPASGADPPKDTPVTGLLSMFSGPQQTSQPRSATQSASQGNELPKEPLGKSLFSMFGGSGSQPSSQQTGSIFGGILGGSSSSSESPAKGLFSMFGAQSPQPPATRVPAAVLTNEQTVKHISSLDESKLQQTPAQSVSSTATKATPAKELPNDSPSQGLLLHSGISSHPSAPLECLPHETVVPSNESHKEPSVNEIPSLSNETISQPFSQQPDSTGHSLSLDSKESKGPQSKDITSVIAGHTLQPDCDPTVSVPKSTQEALPTDDSRLAQSESSKQAHQEDSSAQGVAPPKEEATSGLLSMFSGSGPQNAQSGSILGGIFSGASGSKEVPAKNLFSMFSGPSSQPGAGNAGHNVQNNSSGASAFGELTGKGLFSVFGGSIPQQATPQPSSIFGGILSGVASKDAPGKGLLSMFGGPSSAPSPSQTPTSKPSETEGLLKVASLVSQEDVTEDSKNMGSEEKKTEPTYYDSQHSVMADQRKAASMASFSTDISDKSSDVIGEKIALERSNLDVVSHSNISLTGDDLAKDIESISKQSTKAEVKITECQTQHIQQTNSTETSASEGHPKHSESQKSVLDSSTEAVSGFMSKLFTGASSAPNSSGGLFSQLHSTPTIPKTSVFGFSSSIPTESIKSDIFGMFKSPEAPKTADIKSSITLTSQSLQSVQDQSLLASRDVTLSGDKDEKSQIEPHSSAKEMSCNDASDNVTVATINSTEASSCQLVETVIKEPPEGEVIKEKTVVMVSEEKFTDKSVPVIDNSSKMAQQPQSSETSQSIFGMPGLTASKFGFMSGAADAGKSFGSLFSSPPSIPNTESGKLISGFKSFSAGLFQDEKSVVSKEATPASLFGAKLGFPWQKETPEPPKPQTTPVVTIQPKAQENKVRIEDGTSVKKDHDNLNLEEDKGEITHSVDIKQKTVANFEVTENNTDKSKLIASTPDPPPQKDLEIHIQTPPSTDASSGLQQEKKDLLIPKSPVNSSRFGSSGNLSQASSQLSETGQESAACSELEESYHSYHSTGYRPSRNGHHPTNGHASWGEDEGLKSSQENGKDTSSTLKKEVVSQVDKMPEKSPKSFKDDGLPLPFSPSRVRWLKAINKVRVQLKEGKE--NGDNSRHAWVKAGNGSGIFG---------------IDSMPDLR-KKKAIPLVSDV--SLVQARK--AGIASAMASRSSIKDEELKNHVYKKTLQALIYPISCTTPHNFEVWTATTPTYCYECEGLLWGIARQGMRCTECGVKCHEKCQELLNADCLQRAAEKSSKHGAEDRTQNIIMAMKDRMKIRERNKPEIFEVIRDVFVVSKAIHAQQMKTIKQSVLDGTSKWSAKITITVFCAQGLQAKDKTGSSDPYVTVQVGKTKKRTKTIYGNLNPVWEEKFHFECHNSSDRIKVRVWDEDDDIKSRVKQRLKRESDDFLGQSIIEVRTLSGEMDVWYNLEKRTDKSAVSGAIRLQISVEIKGEEKVAPYHVQYTCLHENLFHHITDVLGQGVVKIPEARGDDAWKVYFDDVPQEIVDEFAMRYGIESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYAHTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSMYRNNFPASSKDRLQDLKSTVDLLTSITFFRMKVQELQSPPRASQVVRDCVKACLNSTYDYIFNNCQELYSRQYPQIGDTHKDDCSPEDQGPSIKNLDFWPKLITLIVSITEEDRNSYTPVLNQFPQELNVGKLSAEVMWSQFSQDMKYAMEEHEKHRLCKSADYMNLHFKVKWLYNEYVKDLPAFKGIVPEYPTWFQQFVLQWLDENEDVSMEFMHGALERDKKDGFQQTSEHALFSCSVVDVFTQLNQSFEIIKKLECPDPKVMALYSRRFAKTIDKVLLQYSAILKKSFPSYCDKEKIPCVLMNNVQQLRVQLEKMFESMGAKQLEESEDEEDEELLEETSEDKPHKADREQKVVVRSKLDTEASDLLNDLQVKLNNVLDELSSTFGNTFQSRIDDCMRQMASLLYQIKGP--VNTNN-----KNQVEADSDNMLRPLMDFLDANLMLFASVCEKTVLKRVLKELWRIVMNSLEKTIILPQGND-TFG--MIFSAAKELGQLSKLKD-----------------------HMS-GEAKSLTPKQCAVMDVALDTIKQYFHAGGNGLKKAFLEKSPELSSLRHALSLYTQTTDTLIKTFVTSQHAQVHNGKGLRITPSEKIQPSRGSGVDKPVGEVSIQIDLFTHPGTGEHKVTVKVVAANDLKWQT-SGMFRPFVEITMIGPHLSDKKRKFTTKSKNNSWAPKFNETFHFILGNEDGPECYELQVCVKDYCFGRADRVVGIAVIQLRDVAPRASCACWCPLGPRIHMDDTGLTVMRILSQRSGDEVAKEFVKLKSDTRSAEEEMTQAAK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O14795-1", "uniprot_id": "UN13B_HUMAN", "id": "O14795-1", "name": "Protein unc-13 homolog B", "aln": "---MSLLCVR---VKRAKFQGSPDKFNTYVTLKVQN-VKSTTVAVRGDQPSWEQDFMFEISRLDLGLSVEVWN----------KGLIWDTMVGTVWIALKTIRQSDEEGPGEWSTLEAETLMKDDEICGTRNP------------------------TPHKILLDTRFELPF---DIPEEEARYWTYKWEQINALGADNEYSSQEES-----QRKPLPTAAAQCSF----------------EDPDSAVDDRDSDYRSETSNSFPPPYHTASQPNASVHQFPVP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VRSPQQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLLQGSSRDS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNDSMQSYDLDYP----------------------------------------------ERR---------------------------------------------------------AISPTSSSRYG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSCNVSQGS-------------SQLSELDQYHEQDDDHRETDS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IHS---CHSSH----------------------------------------------SLSRDGQAGFGEQEK---------PLEVTGQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AEKEAACEPKEMKEDATTHPPP--------------------------------------------DLVLQKDHFLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQES-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FPEENASS-------------------------------------------------------------------------------------------------------------------------PFTQARAHWIRAVTKVRLQLQEIPD--DGDPSLPQWLPEGPAGGLYG---------------IDSMPDLR-RKKPLPLVSDL--SLVQSRK--AGITSAMATRTSLKDEELKSHVYKKTLQALIYPISCTTPHNFEVWTATTPTYCYECEGLLWGIARQGMRCSECGVKCHEKCQDLLNADCLQRAAEKSCKHGAEDRTQNIIMAMKDRMKIRERNKPEIFEVIRDVFTVNKAAHVQQMKTVKQSVLDGTSKWSAKITITVVCAQGLQAKDKTGSSDPYVTVQVSKTKKRTKTIFGNLNPVWEEKFHFECHNSSDRIKVRVWDEDDDIKSRVKQRLKRESDDFLGQTIIEVRTLSGEMDVWYNLEKRTDKSAVSGAIRLQISVEIKGEEKVAPYHVQYTCLHENLFHYLTDIQGSGGVRIPEARGDDAWKVYFDETAQEIVDEFAMRYGIESIYQAMTHFACLSSKYMCPGVPAVMSTLLANINAYYAHTTASTNVSASDRFAASNFGKERFVKLLDQLHNSLRIDLSTYRNNFPAGSPERLQDLKSTVDLLTSITFFRMKVQELQSPPRASQVVKDCVKACLNSTYEYIFNNCHDLYSRQYQLK-----QELPPEEQGPSIRNLDFWPKLITLIVSIIEEDKNSYTPVLNQFPQELNVGKVSAEVMWHLFAQDMKYALEEHEKDHLCKSADYMNLHFKVKWLHNEYVRDLPVLQGQVPEYPAWFEQFVLQWLDENEDVSLEFLRGALERDKKDGFQQTSEHALFSCSVVDVFTQLNQSFEIIRKLECPDPSILAHYMRRFAKTIGKVLMQYADILSKDFPAYCTKEKLPCILMNNVQQLRVQLEKMFEAMGGK-----------------------------------ELDLEAADSLKELQVKLNTVLDELSMVFGNSFQVRIDECVRQMADILGQVRGTGNASPDA-----RASAAQDADSVLRPLMDFLDGNLTLFATVCEKTVLKRVLKELWRVVMNTMERMIVLPPLTD-QTGTQLIFTAAKELSHLSKLKD-----------------------HMVREETRNLTPKQCAVLDLALDTIKQYFHAGGNGLKKTFLEKSPDLQSLRYALSLYTQTTDTLIKTFVRSQTTQ-------------------GSGVDDPVGEVSIQVDLFTHPGTGEHKVTVKVVAANDLKWQT-AGMFRPFVEVTMVGPHQSDKKRKFTTKSKSNNWAPKYNETFHFLLGNEEGPESYELQICVKDYCFAREDRVLGLAVMPLRDVTAKGSCACWCPLGRKIHMDETGLTILRILSQRSNDEVAREFVKLKSESRSTEEGS-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "H9XVP2-1", "uniprot_id": "H9XVP2_DROME", "id": "H9XVP2-1", "name": "", "aln": "MMNTSQLQVTGDTEKKSQLLKKELKINTQEKLIFAENALKSQIKIKEQLRLQQQSTIYASSLLSSSAAGSVRAPLLSQGHLNSIQHNMDFDLAKAQIPEMQPPMSKSPNGLDFSYLSYPSINTNESMISIKSEQQLCQSYNSEQHSDYIISDYMDKIATRISLLETELKFAWRALDLLSTEYGKIWIRLEKLENISIEQQSVVGNLVDLIGASKKELQKVDIERMKVPLYQDEDQLLPLEMEDTLDIDIQSSNRDFDKNLTFENHEKTFVTKHTQATKSEDLMNSAYAIDSHPNFENIDFNG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KNLDIGIIKFGFEKGYEPKQKGNQSDFEAYKESRTKLYSDSDLMLYERQQFLANSARAELMKEFLNGRRVLNEISASSGALSKSSEKDKNLVKPREPLLSEIDDTYVRRSTCELVSPSSNNFFQIAASKTGEGGNQVLPIEDTGG----------------------------------------------TESPANINEVDESFYKNLNEAYRDNELSSEIFKVDALLHQSEATHDHISFIRNQSTSSPVLNNQRVNAITG-----------------------------------------------------------------------------TQPLQTAKACLVTEPNQ-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HLNKEPRKHRKKKHHTNEMDMINKLKCILAQAQSTEIIKRDIEELGSKLSDACVKQTETENKSDNHISTSYLKDDIRKMLNNVIQTLLGEINKIKGLQSLSATQLSQLQNAVWSEERFFQKISLVDKKLTLLLLNPLTVTEELQRLCISNTNEKFVLVIKKLKKNIDTLKKLVGSSLDDFKIDNSHANMTTFHSLNPSHNSNDSSFSAHLLRNNSNLDEQLKILETQEIEIHRKKKIDEIVSG-LSEETYTFNPDMEYKSQHSCTNSTDNIIGFSKNIYNEDEYIKSLRKSLERHNSMIFLLHLQNPEKHKVLADINDAQMDSNRASLSPPPPAPTDTVYLNDAINQITYQQRNGKSDSGLSSMSGWSANSQVSVGLQNYDPACNNILENCSERLQTYHSFPLAENSNFHSFPLSHEQAQTTNQTEFVILEEN-----------------------------------------------LNYIYELSKNLPICSAYENKSIFDMKYEICDSNEIGKFSTVDEMLEWDQLNEPDKQNFSGKRLNSNLMPDLLTAQIPNSISKHNKNTSVNIEYVRQKENKGMDRRSIIEPNIYNGKSEDQICRPCLTDKLVFYPSSNSITDHNSSHDFNCLSQQDQTRIIKEFGSAHLNQDPTNYLDYTSGTYSKAPPEVLTHETN---------------------------------------------------------------------------------------------------------------SSHLEFNHESESLFNSPNTSSYCKQKFVPGTSPAKPSKVWKRLNTILADNLKLKRVSKFNRSLSLPG------------------------------------DVQSQGLQRQPRGQAGSCPFIHKRSNLAGSPVQLSKRIQKLPIRFIGRAKGVPFVRRSSSPDSAVSLDSAADKRFSSEKGLKKKTISSKMSGLMQKAKTYKRHSFVLRRGCNMSDSELEMPDFVSSGNDNSSISTREILLNQSIEVEDEQEDFNYKN------------------------------------------------------------------------------------------------------RCDSKSVLGGSIEKLNGNLTNNLFPIVGDLKKIQSPLPLAVLTEIPSYKDEYSNKSDSIKNSPIEMPKILLETACNQELNLAHSDDDVDKNILANSAKDYVNAPTFSILKTVEDASEP--------------------------------------------------------------------------------------------------------------TMTPLHTTTTTNSSLNVTSALWVTQQCLDLPNYPGWGSREDDDNRSQHSARTLSS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SRRQSTEDSIDTDDEYFYYELRQLEEQEKQRAHNSAIPSCERQNDNDVLFSQIGQLLQNDVNGGDGFRHSNGCNDGEDAIIFSPSESVKLRMSEVFKELKS---VVSLNPSVNNDATFEGVPIVKPTYEKLETVSDLHSAWQDVNG---------------------------------------------------------------------------------------------------------------------------------DLQIAASDIDSNEDLVGNKGRETPTYNKQRKLRRLKKKTRDRKINISKNATSSSSSCHSENECNTPLGQCTQKSVAEKDTNDISNKSEASSETSGPDTPAELSDVDISETENGLRAD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGQNIDNMRGNSGSLLKVNRKYLLQFDVDHSLINQPLETSQYN------------------------------------------------------------------------------------------------------------------------------------------------------THMLENITSASIPSQNRQIDSKTLMSQSSHADGSQAVG-----------------------------------------------------------------------------------------------------------------NETAVGLSSSKWKLLKTLKERKIEEKNNQDKIKEDEMIKDRDKNGGGPGEVGLRTNGHPGDNPFYSNIDSMPDIRPRRKSIPLVSELVLKTMAATKRNAGLTSAVP-RATLNDEDLKMHVYKKALQALIYPISSTTPHNFLLWTATSPTYCYECEGLLWGIARQGVRCTECGVKCHEKCKDLLNADCLQRAAEKSSKHGAEDKANSIITAMKDRMKQREREKPEIFELIRAVFSVEEKSHAGHMKAVKQSVLDGTSKWSAKIAITVICAQGLIAKDKSGTSDPYVTVQVSKVKKRTRTMPQELNPVWNEKFHFECHNSSDRIKVRVWDEDNDLKSKLRQKLTRESDDFLGQTIIEVRTLSGEMDVWYNLEKRTDKSAVSGAIRLHISVEIKGEEKVAPYHVQYTCLHENLFHYLCEEN-TGMVKLPTQKGDDAWKLYFDEIPEEIVDEFSMRYGIENIYQAMTHFHCLSAKYLCPGVPAVMSTLLANINAYYAHTTASSAVSASDRFAASNFGKEKFVKLLDQLHNSLRIDLSMYRNNFPASSPEKLMDLKSTVDLLTSITFFRMKVQELSSPPRASTVVKDCVKACLRSTYQFLFENCYELYNREFQVD--PNEAKRAPDDHEPKLDSVDFWHKLIALIVSVIDEDKNSYGTVLNQFPQELNIGQLSASSMWHLFAVDMKYALEEHEQHRLCKSSAYMNLHFRVKWLYSNYVKEVPPYKGAVPDYPAWFEPFVMQWLNENDDVSLEYLHGAFKRDKKDGFQKSSEHALFSNSVVDVFTQLTQCFDVVSKLECPDPEIWKRYMRRFAKTIVKVLIAYADIVKLEFPEHMKDERIACILMNNIQQLRVQLEKMFESMGGD-----------------------------------KLEEDAANILKELQQNLNSALDDLASQFAISLEPRITQSVRELGDMLLSIKGGSGTLAAGNLAAQRNAVAVEADEVLRPLMDLLDGSLTLYAQSCEKTVLKRLLKELWKIVMRILEKTIVLPPMTDKTMMFKHLTDNAKNLASNAKIEDMGRLFKSHMAGKQDVKSALSGVMDISKEVEKNLSPKQCAVLDVALDTIKQYFHAGGNGLKKTFLEKSPELQSLRYALSLYTQMTDTLIKTFISSQVHEVD-----------------LENSEESVGEISVQIDLFSHPGTGEHKVNVKVVAANDLKWQIPSGMFRPFVDINLIGPHLQEKKRKFATKSKSNNWSPKYNESFSFTIGNEEQLDFFELHICVKDYCFARDDRLVGVAVIPLKDISEKGSVACWLPLMRRIEMDETGWTILRILSQRNNDEVAKEFVKLKSEIRQEPTMGT----", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * * *:::: *:*: .* . : . .: : :: : :*. :: * *. . .* * :... *. *.. . :: *. : . :.: . :. :.: ** *.:::.: :: . * : *::: :. .:: : : * . : : * ::. : *: .: : . ..: :.::: : : * *:: :*: .*. . * .*. : * * . *:. * ** * . . * . : .... : .: :. .* * * . : . * .*: : :. : : * .. .. : . : * .: . .*. :: :: : ::::.: ::: :: : . * * . * * ******:* ::*.:****:: . : : * **::**:. *::::**:** *****:*********.****** :*:**:*************:****:**:**********::**************.******:::.** ******* ***:******:** ** *.: *. :**::***************:***.***** ****:*:*********.*.****:*: :*****:**********************:*:**:::*:*.*********:********************************:*.*************************:: : * * :* :******:***: .:******:******.******** ***:**:*************************: ***************:***************** *******.* ::* **********************.****** **:*******.***:::*:** :**.::: . . :: *.: .:*** ***:****: :**:*** .**.*******:*::**. ** *: *****:****:.:****: ******:****:.:**:::* :* **:**:**: **:***:**:***:*:::*.::***:****::******* *********.*.*::: *******.: * ******* ***: *: *:. .** : .*::.*:****:************:**.. :*: :*:: *::** :**..**:*: *. ::: ** :.:*::..:* .::* . . : . ::*.:******:**..* *:* ********:*****::**. :*: *:** * : **:*. :*::* .: :.*:******:*:****:*************:******:*.***:******* ********: ** : . :..***:*:*:***:*********.************ :*******::.::*** .:*****:****.*.*:**:**:* * :***: : :**::*******.* **::*:**: *:*:: :.* *** ** :*.**:** *::******..****:*******: *. ", "identical_positions": 813, "similar_positions": 432, "identity": "15.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120502-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0KW69-1", "uniprot_id": "A0ABK0KW69_RAT", "id": "A0ABK0KW69-1", "name": "Neuron navigator 2", "aln": "MPAILVASKMKSGLPKPVHSAAPILHVPPARTGPQPCYLKLGSKVEVSKTAYTSQIPLKS---QGLQEPTGEGLPLRKSSSLENGFDTQ--IYTDWANHYLAKSGHKRLIKDLQQDVTDGVLLAQIIQVVANDKIEDINGCPKNRSQMIENIDACLNFLAAKGIN-TQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQQ--QPEKQHLSSSPLPPAGSQVAGAPSQCQSGILQQQGLATPQAPCQPLQPASHQQAKTQAEMQSSASAKDSCQSKIIRFTLGQKKISRLPGPTARVAAAGSEAKTRGGSTAANNRRSQSFNNYDKSKPVPSPPQPAPPSNHEKEPLASSASSHPGMSENVPASLES-SPSIPVNCS-SSAIPQPSMTSKPWRSKSLSVKHSATSSMLSVKPAGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKAG---------EGSASRDTSCERLEILPSFEESEELEV-ANRAPPTAGPASSSPKIALKGIAQRTFSRALTNKKSSPKGNEKEKEKQQREK----EKETGKDLTKRVSVTDRPDLKEEPKEELSGVVVTEMP--KKSSKIASFIPKGGKLSSTKKEATAPSHSGIPKPGMKNMPG---KSPSAPIPPKEGERSR-GKLSSGLPPQKPQLDSRHSSSSSSLASSEGKGPGGTTLNHSISSQTVSGSIGTTQTTGSNTVSVQLPQPQQQYSHPNTATVAPFLYRSQTDTEGNVTAESSSAGVSMEPSHYTKSGQPALEELTAEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEISGRSILSLTGRPTPLSWR--LGQSSPRLQAGDAPSMGNGYPPRANASRFISAEAGRYVYSAPLRRQLASRGSSICHVDVSDKVGDEVDLEGISMDAPGYMSDGDVLSKNIRTDDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRRNLD--VQTDAEKHSQVERNSLWSGDDIKRSDGGSDSGVKMEPGSKWRRNPSDMSDESDKSVSGKKNPVLSQTGSWRRGMTAEVGITMPRTKPSAQTG---TLKTSGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKTLPSSSRTPTANANSFGFKKQSG--------SAAGLAMITASGATVTSRSATLGKIPKSSALVGRSTG-RKTSMDG-APNQDDGYLSLSSRTNLQYRSLPRPSKSNSRNGAGNRCSTSSIDSNMSSKS---AGLPVPKLREPSKTSLGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPATQPVSNSTQATLQPGTKYTDVASPTLRRLFGGKPTKQVPIATAETMKSAVVISNPHATMTQQ----GNLESPSGSGVLSSGSSSPLYS-KNVDLNQSPLASSPSSAHSGPSNSLTWGT---SSSAVSKDGLGFQSVSSLHTSCESIDISLGSGGGLSHNSSPGPVASTKEDSLMPFVRTSSVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDTKEWFRSHSAGGLQETATNSPFSSGSSVTSPSGTRFNFSQLASPTAVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEE---------------------------------VHGSSLSLVSSTSSIYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCK-------GNGSAQATDLRIRRQHSSDSVSSINSATSHSSVGSNIES--DSKKKKRKNWVNELRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNAHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSIS-ASPRQSLGLSQHSLNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEAMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTILVTVKGLTENSLDSLVFESLIPKPILQRYVSLLTEHRRIILSGPSGTGKTYLANRLSEYVVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCK-YHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNAELVKIINWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRR-APWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSLPREGSTSKQVPPSDTEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSSLESTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "V9GX91-1", "uniprot_id": "NAV2_MOUSE", "id": "V9GX91-1", "name": "Neuron navigator 2", "aln": "MPAILVASKMKSGLPKPVHSAAPILHVPPARTGPQPCYLKLGSKVEVSKTAYTSQIPLKS---QGLQEPTGEGLPLLKSSSLENGFDTQ--IYTDWANHYLAKSGHKRLIKDLQQDVTDGVLLAQIIQVVANDKIEDINGCPKNRSQMIENIDACLNFLAAKGIN-TQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQQQQQPEKQPLSSSPLPPAGSQVAGAPSQCQAGTPQHQGLATPQAPCQLLQPVSHQQGKTQVEMQS-----------------------RLPGPTARVAAAGSEAKTRGGSAAANNRRSQSFNNYDKSKPVTSPPPPAPPSNHEKEPLASSASSHPGMSENVPAPLEN-SPSVPVNCS-SSAIPQPSMTSKPWRSKSLSVKHTATSAMLSVKPAGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKAG---------EGSASRDTSCERLEILPSFEETEELEATANRALSTVGPASSSPKIALKGIAQRTFSRALTNKKSSPKGNEKEKEKQQREKEKEKEKEKGKDLTKRVSVTDRPDLKEETKADLSGVAVTEMP--KKSSKIASFIPKGGKLNSTKKEATAPSHSGIPKPGMKNVSA---KSPSAPIPPKEGERSR-GKLSSGLPPQKAQLDSRHSSSSSSLASSEGKGPGGTSLNPSISSQTVSGSVGTTQTTGSNTVSVQLPQPQQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSAGVSMEPSHYTKSGQPALEELTE-DPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEISGRSILSLTGRPTPLSWR--LGQSSPRLQAGDAPSMGNGYPPRANASRFISAEAGRYVYSAPLRRQLASRGSSICHVDVSDKADDDVDLEGISMDAPGYMSDGDVLSKNIRSDDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRRNLD--VQTDAEKHSQVERNSLWSGDDIKKSDGGSDSGVKMEPGSKWRRNPSDMSDESDKSVSGKKNPVLSQTGSWRRGMTAEVGITMPRTKPSAPTG---TLKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKTLPSSSRTPTVNANSFGFKKQSG--------SAAGLAMITASGATVTSRSATLGKIPKSSALVGRPTG-RKTSMDG-APNQDDGYLSLSSRTNLQYRSLPRPSKSNSRNGAGNRCSTSSIDSNMSSKS---AGLPVPKLREPSKASLGSSLPGLVNQTDKEKGISSDSESVASCNSVKVNPATQPVSSSAQATLQPGTKYADVASPTLRRLFGGKPTK--PIATAETMKSAVVISNPHATLTQQ----GNLESPSGSGVLSSGSSSPLYS-KNVDLNQSPLASSPSSAHSGPSNSLTWGT---SSSAVSKDGLGFQSVSSLHTSCESIDISLGSGGGLSHNSSPGPVASTKEDSLMPFVRTSSVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWFRSHSAGGLQDTATNSPFSSGSSVTSPSGTRFNFSQLASPTAVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEE---------------------------------VHGSSLSLVSSTSSIYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCK-------GNGSAQATDLRIRRQHSSDSVSSINSATSHSSVGSNIES--DSKKKKRKNWVNELRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNAHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSIS-ASPRQSLGLSQHSLNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEAMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIVHVDPVSQLGLSSDSVLGYSIGEIKRSNASETPELLPCGYLVGENTTILVTVKGLTENSLDSLVFESLIPKPILQRYVSLLTEHRRIILSGPSGTGKTYLANRLSEYVVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCK-YHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNAELVKIINWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRR-APWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSLPREGSTSKQVPPSDTEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSSLESTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IVL1-1", "uniprot_id": "NAV2_HUMAN", "id": "Q8IVL1-1", "name": "Neuron navigator 2", "aln": "MPAILVASKMKSGLPKPVHSAAPILHVPPARAGPQPCYLKLGSKVEVSKTTYPSQIPLKSQVLQGLQEPAGEGLPLRKSGSVENGFDTQ--IYTDWANHYLAKSGHKRLIRDLQQDVTDGVLLAQIIQVVANEKIEDINGCPKNRSQMIENIDACLNFLAAKGIN-IQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQQP----QKQHLSS-PLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPHQPAPHQQSKAQAEMQSSASSKDSSQSKIIRFTLGQKKISRLPGPTARVSAAGSEAKTRGGSTTANNRRSQSFNNYDKSKPVTSPPP--PPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTNCSTSSAIPQPGAATKPWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLKLFNSKGGSKAG---------EGPGSRDTSCERLETLPSFEESEELEA-ASRMLTTVGPASSSPKIALKGIAQRTFSRALTNKKSSLKGNEKEKEKQQREK----DKEKSKDLAKRASVTERLDLKEEPKEDPSGAAVPEMP--KKSSKIASFIPKGGKLNSAKKEPMAPSHSGIPKPGMKSMPG---KSPSAPAPSKEGERSRSGKLSSGLPQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISSQTVSGSVGTTQTTGSNTVSVQLPQPQQQYNHPNTATVAPFLYRSQTDTEGNVTAESSSTGVSVEPSHFTKTGQPALEELTGEDPEARRLRTVKNIADLRQNLEETMSSLRGTQVTHSTLETTFDTNVTTEMSGRSILSLTGRPTPLSWR--LGQSSPRLQAGDAPSMGNGYPPRANASRFINTESGRYVYSAPLRRQLASRGSSVCHVDVSDKAGDEMDLEGISMDAPGYMSDGDVLSKNIRTDDITSGYMTDGGLGLYTRRLNRLPDGMAVVRETLQRNTSLGLGDADSWDDSSSVSSGISDTIDNLSTDDINTSSSISSYANTPASSRKNLD--VQTDAEKHSQVERNSLWSGDDVKKSDGGSDSGIKMEPGSKWRRNPSDVSDESDKSTSGKKNPVISQTGSWRRGMTAQVGITMPRTKPSAPAG---ALKTPGTGKTDDAKVSEKGRLSPKASQVKRSPSDAGRSSGDESKKPLPSSSRTPTANANSFGFKKQSG--------SAAGLAMITASGVTVTSRSATLGKIPKSSALVSRSAG-RKSSMDG-AQNQDDGYLALSSRTNLQYRSLPRPSKSNSRNGAGNRSSTSSIDSNISSKS---AGLPVPKLREPSKTALGSSLPGLVNQTDKEKGISSDNESVASCNSVKVNPAAQPVSSPAQTSLQPGAKYPDVASPTLRRLFGGKPTKQVPIATAENMKNSVVISNPHATMTQQ----GNLDSPSGSGVLSSGSSSPLYS-KNVDLNQSPLASSPSSAHSAPSNSLTWGTNASSSSAVSKDGLGFQSVSSLHTSCESIDISLSSGGVPSHNSSTGLIASSKDDSLTPFVRTNSVKTTLSESPLSSPAASPKFCRSTLPRKQDSDPHLDRNTLPKKGLRYTPTSQLRTQEDAKEWLRSHSAGGLQDTAANSPFSSGSSVTSPSGTRFNFSQLASPTTVTQMSLSNPTMLRTHSLSNADGQYDPYTDSRFRNSSMSLDEKSRTMSRSGSFRDGFEEESWEKSSVDNFVSRLHSSLHFSLPLFHHARYELVHGSSLSLVSSTSSVYSTPEEKCQSEIRKLRRELDASQEKVSALTTQLTANAHLVAAFEQSLGNMTIRLQSLTMTAEQKDSELNELRKTIELLKKQNAAAQAAINGVINTPELNCK-------GNGTAQSADLRIRRQHSSDSVSSINSATSHSSVGSNIES--DSKKKKRKNWVNELRSSFKQAFGKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSTGSTPLLRNSHSNSLISECMDSEAETVMQLRNELRDKEMKLTDIRLEALSSAHQLDQLREAMNRMQSEIEKLKAENDRLKSESQGSGCSRAPSQVSIS-ASPRQSMGLSQHSLNLTESTSLDMLLDDTGECSARKEGGRHVKIVVSFQEEMKWKEDSRPHLFLIGCIGVSGKTKWDVLDGVVRRLFKEYIIHVDPVSQLGLNSDSVLGYSIGEIKRSNTSETPELLPCGYLVGENTTISVTVKGLAENSLDSLVFESLIPKPILQRYVSLLIEHRRIILSGPSGTGKTYLANRLSEYIVLREGRELTDGVIATFNVDHKSSKELRQYLSNLADQCNSENNAVDMPLVIILDNLHHVSSLGEIFNGLLNCK-YHKCPYIIGTMNQATSSTPNLQLHHNFRWVLCANHTEPVKGFLGRFLRRKLMETEISGRVRNMELVKIIDWIPKVWHHLNRFLEAHSSSDVTIGPRLFLSCPIDVDGSRVWFTDLWNYSIIPYLLEAVREGLQLYGRR-APWEDPAKWVMDTYPWAASPQQHEWPPLLQLRPEDVGFDGYSMPREGSTSKQMPPSDAEGDPLMNMLMRLQEAANYSSPQSYDSDSNSNSHHDDILDSSLESTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9QCH2-1", "uniprot_id": "A0A8M9QCH2_DANRE", "id": "A0A8M9QCH2-1", "name": "", "aln": "MNRTNEQTFLWQRELARSHRDFGFGNTGTGRR-ALDCYLKKCCGYFKECFRKMSES--------GAEASASQ---PQKRKPVIHGLEDQKKIYTDWANHYLAKSGHKRLIKDLQQDVSDGVLLAEIIQVIANEKIEDINGCPKSRSQMIENIDACLSFLAAKGVN-IQGLSAEEIRNGNLKAILGLFFSLSRYKQQQQTS----RQTHTQHTHSHTPLIQQSSAPAQLIS-TPHGPHSHKTQTDMQSRDGSQSKLKFSIGQKKSS----------------------RLPGPTSRMSTAGSESSPRGSISSAGNRRSLVFS--DKAK---------PAAAQAKE--SSESVTDPALSS----ACTSLSTSTVASSSSSSAIPQPNSSSKPWRIKSQNSKHTSATSTGLSTKSDLQAKQPVPAEAPPKAVPQKSMLEKLKLFNSKGGSKSSTQTEGAVTPTGGKDAALVLERVETGSNTEPIEEMDGNVRPTNGAVSVTTSSPKIALKGIAQRTFSRALTAKKASAKSSEKEKGKD-------------KNASKRGSPSEKVEEVKEEVVSSSVVTAPSEPEPRKASKIASFIPKGGKVGGAKKDGPAPVQSGIPKPGSKSAGNGAVKGSALPLGGKDNERPRSVRLGAGLGLHR---DSRHSSSSSSLASTEGKG------HPMHSAAPVAN---GTQSTASNTVSVQLPQPQQQYNHPNTATVAPFMYRTQNEADGNMGTNLSSGCRSSDSGSFSKTNQSSTEDLSGEDPETRRLRTVKNIADLRQNLEETMSSLRGTQITHSTLETTFDGGVTTEMSSRNILSMASRPSPLSWASRMGQSSPRLQAGDAPSVGNGYQSRSGG---VAPGQGRYLYQAPLRKQLAARGSGLCGLELGDRV-EDLELAGVGLEMSGYMSDGDVLSKNARTDELSSGYMTDGGLSLYTRRLNRLPDGMAMVRENLQRNASTSQGDADSWDDSSSVSSGISDAID---TDDINTSSSISSYANTPAASRKGLNGQPQTDAEKHSAAERNTSRSIDEVKKSDGGLDCSIKSDSGLKWRRNPSDVLEESDKSSSGRKTAPVTQTGSWRRGMSAQVGVTVPRTKSTSVSSGSSIIKTQGTGKTDDAKVSEKGRMSPSSNILQHSSSDTGRSSGDEAKKTTAG--RVPTS---TFGFKKPNGVHNPSNVITTASITLVTASGAIITSGSATLGKIPKSSALLVGGRGSLKGAVDGLLPPQEDGYLSPSARSTLQYRSLPRPSRSGAAARNGNRSSTSSIESSLLTRAPLLTAITANKPRDPGPKTNGHAIQ--ANQTDKEKGVASDIDSTRTNPIVSGGGAAT-----IPQTARQGNKYSEVSSPTLRRLFGGKAAKQAPVTTAESMKNSVVISNPHATLGHTQSSGGPLDSP--STVPGSGGSSPLYGGRGASIGGSEQASSPGSVYSTGTG--TWGT-----TISSSSALGYPSVSSMHTSSESIDMSVGSG-------------HPRDDVHPALMRTGSAKTGMSESPLSSPSNSPKFNRNTLPRKQD---------------RYAPSPQLR-QEEARDWLRSHSAGGLQDSASNSPFSTGSSLTSPSGTRFNFAQLGSPTTGAQINLAS---LRNNSLTSQDNPLDSHADSRLRNSCMSLDEKTRTMSRSGSFRDGFEE---------------------------------VHGSSLSLVSSTSSVYSTTEEKSQSEIRKLRRELDASQEKVSALTTQLSANAHLVAAFEQSLGNMTIRLKSLTMTAEQKDSELNELRKTIELLKKQNAVAQAAINGVINTPELTCKSERTGNNGSGLGAPPDLRMRRQHSSDSVSSITSATSHSSLGSNMDNPDSSSKKKKKNWL---RSSFKQAFSKKKSPKSASSHSDIEEMTDSSLPSSPKLPHNGSGSTALLRRNTHSSSILSDCLDGEAETVMQLRNELREKEMKLTDIRLEALSSAHQLDQLREAMNRMQGEIEKLKSENDRLKVESHASG-SRASSQVSVYNPTPTPTPGLSQHSLNLTESTSFDMLLDDSGGDGSSRKESRHVKIVVSLQEDVMWKEDCRTRHFLIGCIGVSGKTKWDVLDGVVRRLFKEYIRHVDPVSHLGLGSDSVEGYRIGDVVRCSGANTPELLPCGYLVGENDTINISLKGVNSQSQDSLVFETLIPKPMLQRYVSLLQEHRRIILSGPSGTGKSYLAHRLAEHLALQEGKLPSDSNIVTFNVDHKSSKELRQYLANIVEQCSAAGQDTEAPLVLILDNLHHISSLGEIFSGLLNCR-YQRCPYIIGTMSQATSSAPNLQLHHNFRWVLCANHMEPVKGFLGRYLRRKLIETEIGNRTRNPELVKIIDWIPQVWQHLNRFLEAHSSSDVTIGPRLFLSCPMDVDGSRVWFTDLWNYSIIPYMLEAVREGLQLYGRR-AAWEDPALWVLETFPWAASHQHPDWPALLQLRPEDVGFDGYSASREG-VSKQSTQSDSDADPLMNMLLRLKEAASCSSPQSYDSDSNSNSHHDDILDSSLESTL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIQ9-1", "uniprot_id": "NAV_DROME", "id": "Q9VIQ9-1", "name": "Protein neuron navigator", "aln": "-------------------------------------MLARCVSYQGSCDNINGILT-----------------------------RDYAEIYTDWANYYLERAKSKRKVTDLSADCRDGLLLAEVIEAVTSFKVPDLVKKPKNQQQMFDNVNSCLHVLRSQSVGGLENITTNDICAGRLKAVLALFFALSRFKQQAKQT---------KSIGVGCGGGVGGSSSTLTGSGSVLGIGIGGLRTPGSSLNQDKNQQEQQQQQQQQQ-----------------------TPQQLAQSLENGNEMVNRQIAPAYAKVNG--------------------GTAIPLPATVMVQRRCPPDKVRPLPPTPNHTPSIPGLGKSGSDFNTSRPNSPPTSNHTIQSLKSGNNNSLRPPSIKSGIPSPS---SPQTAPQKHSMLDKLKLFNKE-----------------KQQNAVNAASVASKTQIQSKRTSSSSGFSSARSERSDSSLSLNDGHGSQLKPPSISVSSQKPQPK-------------------------TKQSKLLAAQQKKEQANKATKLDKKEKSPARSLNKEESGNESRSSTMGRTGKSSLVRAVGGVEKNTPKTSSK-----SSLHSKSDSKSSLKAPQLLQSPSSGGLPKPIAAIKGTSKLPSLGGGAGHLPAAESQQNQQLLKRETSDISSNISQPPPAEPPISTHAHIHQNQTPPPPYYANSQPTSHISSHGFLSEPSTPQHSSGIYGSSRLPPPKSALSAPRKLEYNAGPHILSSPTHHQRQGLPRPLVNSAPNTPTASPNKFHTIPSKIVGTIYESKEEQLLPAPPPASGGSSILPMRPLLRGYNSHVTLPTR----GARGGHHPHQSYLDFCESDIGQGYCSDGDALRVGSSPGGSRFHDIDNGYLSEG---SSGLNGPSSSAGGISPG---KHFLSMMRARTQLPTTIEERIRNSRGSLDSIGTAANGSSAASQASSSGGSTTTHAQNNNNNNNNNSGGGAKMDGSPHHRPGSRNGRDNWSKMPEPLNGQKVEKSDKSSPSRRSMGGG-----GSGSSSKQGSPSSSSRTKGVPPSFGYVKRANGSIASTAEQQNIAMMMAAG---------------GAGANGLPCGRTAHVSAVPRTASGRKVAGGTQTLPNDMNKLPPNTQHRSFSLTGP----------TATQLSQSIRERLATGSHSLPKPGSDLHVFQHRISNRGGTRHDGSLSDTQTYAEVKPEYSSYAMWLKHSNTAGSRLSDGESVEQLQIGSPALTRHG--HKMIHNRSGGPGQMAG--------QMSGNESPYVQSPRMNRSNSIRSTKSEKMYPSMMSRAGEVEIEPYYCLPVGTNGVLTAQMAAAMAAQSQAAQGNPGVGVNVGGVAWSQP-----TSPTPLTRGPFNTAAGASVLSPTHGTTSAAGLVGPGGGAGGGAMVGHRLTYP-------KKNDEVHGSAASLLSGGSSLYGNAEERQAHEIRRLKRELQDARDQVLSLSSQLSTNAHVVTAFEQSLSNMTNRLHQLTATAERKDGELTDMRQTIELLRKQSIQAGLTTAHMQSMGVQTQGQGQVQGQALGQALGQPGSDQKP------------PNSGSQRAINANNGSMPLGMQRQHSTDSMCSLNSISSGCSAAQDKNKANKKKGWLRSSFTK--------------------------------AFSRNAKISKTSRHVGHHHHHNHSQQELASGKLPLHNGHGEPLGLASLATQPAPPLPNSKQSSPAKTVTLIDNAKPIDAIDQEDQHVVEDLKKQLREKDLVLTDIR------------------LEALSSASQLESLKEMMNKMRAEMMSLKHNNER---------LQKLVTTRSLAGSEASLGQAISPNGSVAGSSEVSRRYSLADSNSRPPMELPAR-----------------LSEELELEEDCLPPAPAPEQPPPPAPNGVSVAPLSPSTHVDLTPPPPALEAAPMASPVHMASATEELADVCDGKKIAIACYLG-----QPEAFAKYCEELQELDGFYANGHEADSQSQSERKSNYT--------------SASCNEFVIACTYISGKTTWQNLDYVVRKTFKDYVARIDPGTNLGLNTDSITSYHLGEAKRGPEMGFPELLPCGYIVGSVRTLYICLQGVG-----SLAFDSLIPRSIVHRYISLLTEHRRLILCGPSGTGKSYLARRLAEFLVARSARGNPSEAIATFNVDHKSSKDLRQYLGHIAEQAAIANGVSELPSVIILDNLHHASALGDVFSCLLSAGPANKLPCIIGTMSQATCNTTNLQLHHNFRWVLTANHMEPVKGFLGRFLRRRLFQLELQTQHPQPELAAVLAWLPSVWQHINRFLEVHSSSDVTIGPRLFLACPMDLKDSQVWFTDIWNYHLSPYLVEAVREGVQLYGRRGGAWNDPSAFIRNSYPWPYGPD--SVPPLRQINAEDVGLEGVALTNGD-----------QQDPLLNMLMRLQEAANYSEAQDQESDCASLDSNVTPESSAGAE--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . . *******:** :: ** : **. * **:***::*:.::. *: *: **.:.**::*:::** .* ::.:. :.:::::* *.***:*.***:***:*** : . ..:.: : :: . : : : :. * :: *.* * .: : .. : * . . . :.* . .* : . : * :: . ::. * . ::***:******.: . : .. : . . : :* . :* :. * ::: :*.. * :*: . : :: . . * .: :. .:...:. : *. . .*: * *. .: .. . : :* . ..:*.*.* * . . . : .:. *:. ..: * . : : * * :. .*: .:* :. . *. . ... :.: . . : *. . .: :* . : :. . .: : .* :: : * . . : : . *. . .*. * *.: . . . *:: :.: * : *.. * . :. .. . **:*:* *.. . . ::* :: * : : * :. . * **: . .. .: :.**.:* *.: . *. *.... .. :. * . . : :.. : . :.:::** . . . * .... .:.. * *.:.. .. * :*. : .. : :. . :. .. :* . : :. . :. . ..:. .. . . .*. . :. : : ::: * :* * .. :. . : .. : : * ... . * :.. :.: *: . .* * :: : : *. : : :.:*. .. : . * :. * * . .: . : * : .* :. .: : :* .:...:.: . . : ... ... . ... . *.:*: :. .*: . . .::: : .: :: * . : :: : * . ::. : : . * . .:::. * :* * ...:. .* .* *.: :* : .: .. . : . : ... : ::*.:: .:.* :*..* : . .: :* : .::.*.*: . : *. .: : .*:: : * :. :** *: * . : . : *.* :.: : :: ::: . : *. .. . ..:*. :: .. :.: * . :.. .* .. : .:*: **:. : * .:*. * .::**. .. :** . :*: :: * : : : ..: : .**.: ::* . . : . . : :. .. .: . : . .::::. :* * .: .::. . .. ..:. .. . *:*.* :****.*: ** ***: **:*: ::** ::***.:**: .* :*: * ********:**. *: : ::*: **.*::***:.:::**:*** ****:**.*******:***.**:*.:. :..: .. *.**********:*****.::.:*. . : * *:******* *:**::*. **.. :: * *****.***..:.************ *** *********:***:*:: *: : : **. :: *:*.**:*:*****.**************:**:*:..*:*****:*** : **::******:****** ..*:**: :: :::**. . : . *.* *:..****::* : .. . : ***:***:**:***. *..*. :**. * . : .*: . ", "identical_positions": 412, "similar_positions": 753, "identity": "16.13%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120503-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LSV0-1", "uniprot_id": "F1LSV0_RAT", "id": "F1LSV0-1", "name": "Semaphorin-4B", "aln": "MTSPIGVTAPICCHGNCPTFPASIGFTSCLYLGAVTSQPKKQMLPDLRPFFSLSPLVSIALSHAELHWPSVVSPDASHDSSQQSHSPSSGSGGGGQGKDSGPNRGAGLQPETPLEQPEPEDAAPAAVRAPRAAMGRASRSADLLSALQ--LLLLLLRTTTAR-ALGPRISVPLDSEERLIRKFEAENISNYTALLLSQDGKTLYVGAREALFALNSNLSFLPGGEYQELLWSADPDRKQQCSFKGKDPKRDCQNYIKILLPLNSSHLLTCGTAAFSPLCAYINTASFTLARDEAGSVLLEDGKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQ-SPRPTKTESSLNWLQDPAFVASAYVPESLGSPIGDDDKIYFFFSETGQEFEFFENTIVSRVARVCKGDEGGERVLQQRWTSFLKAQLLCSRPDDGFPFNVLQDVFTLNPNPQDWRKTLFYGVFTSQWHRGTTEGSAICVFTMNDVQKAFDGLYKKVNRETQQWYTETHPVPTPRPGACITNSARERKINSSLQLPDRVLNFLKDHFLMDGQVRSRLLLLQPQARYQRVAVHRVPGLHSTYDVLFLGTGDGRLHKAVTLDSRVHIIEELQVFPQGQPVQNLLLDSHGGLLYASSHSGVVQVPVANCSLYPTCGDCLLARDPYCAWNGSTCKLLSLYQPDLASRPWIQDIEGANTKELCN-------------------ISSAKARSFKPG--KPCKQVQIQANTVNTLACPLLSNLATRLWLHNGAPVNASASCRVLPSGDLLLVGSQQGLGVFQCWSIEEGFRQLVASYCPEVKEDGVMDQNDQSDGTPVIIN---TSRVSAPAGGRASWGADKSYWNEFLVMCTLFGLAVVLLVLFFLYRNRDGMKLFLKQGECASVHPKTRPAVLPPETRPLNGVGPPSTPLDHRGYQALSD------SSPGPRVFTESEK----RPLS---IQDSFVEVSPVCPRPRVRLGSEIRDSVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q62179-1", "uniprot_id": "SEM4B_MOUSE", "id": "Q62179-1", "name": "Semaphorin-4B", "aln": "-------------------------------------------------------------------------------------------------------------------------------------MGRASRSAVLRRALLLLLLLLLLRTTTTR-ALGPRISVPLGSEERLIRKFEAENISNYTALLLSQDGKTLYVGAREALFALNSNLSFLPGGEYQELLWSADADRKQQCSFKGKDPKRDCQNYIKILLPLNSSHLLTCGTAAFSPLCAYIHIASFTLAQDEAGNVILEDGKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQ-SSRPTKTESSLNWLQDPAFVASAYVPESLGSPIGDDDKIYFFFSETGQEFEFFENTIVSRVARVCKGDEGGERVLQQRWTSFLKAQLLCSRPDDGFPFNVLQDVFTLNPNPQDWRKTLFYGVFTSQWHRGTTEGSAICVFTMNDVQKAFDGLYKKVNRETQQWYTETHQVPTPRPGACITNSARERKINSSLQLPDRVLNFLKDHFLMDGQVRSRLLLLQPRARYQRVAVHRVPGLHSTYDVLFLGTGDGRLHKAVTLSSRVHIIEELQIFPQGQPVQNLLLDSHGGLLYASSHSGVVQVPVANCSLYPTCGDCLLARDPYCAWTGSACRLASLYQPDLASRPWTQDIEGASVKELCK-------------------NSSYKARFLVPG--KPCKQVQIQPNTVNTLACPLLSNLATRLWVHNGAPVNASASCRVLPTGDLLLVGSQQGLGVFQCWSIEEGFQQLVASYCPEVMEEGVMDQKNQRDGTPVIIN---TSRVSAPAGGRASWGADKSYWNEFLVMCTLFVFAMVLLFLFFLYRHRDGMKLFLKQGECASVHPKTRPIVLPPETRPLNGVGPPSTPLDHRGYQALSD------SSPGPRVFTESEK----RPLS---IQDSFVEVSPVCPRPRVRLGSEIRDSVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPR2-1", "uniprot_id": "SEM4B_HUMAN", "id": "Q9NPR2-1", "name": "Semaphorin-4B", "aln": "------------------------------------------------------------------------------------------------------------------------MLRTAMGLRSWLAAPWGALPPRPPLLLLLLLLLLLQPPPPTW-ALSPRISLPLGSEERPFLRFEAEHISNYTALLLSRDGRTLYVGAREALFALSSNLSFLPGGEYQELLWGADAEKKQQCSFKGKDPQRDCQNYIKILLPLSGSHLFTCGTAAFSPMCTYINMENFTLARDEKGNVLLEDGKGRCPFDPNFKSTALVVDGELYTGTVSSFQGNDPAISRSQ-SLRPTKTESSLNWLQDPAFVASAYIPESLGSLQGDDDKIYFFFSETGQEFEFFENTIVSRIARICKGDEGGERVLQQRWTSFLKAQLLCSRPDDGFPFNVLQDVFTLSPSPQDWRDTLFYGVFTSQWHRGTTEGSAVCVFTMKDVQRVFSGLYKEVNRETQQWYTVTHPVPTPRPGACITNSARERKINSSLQLPDRVLNFLKDHFLMDGQVRSRMLLLQPQARYQRVAVHRVPGLHHTYDVLFLGTGDGRLHKAVSVGPRVHIIEELQIFSSGQPVQNLLLDTHRGLLYAASHSGVVQVPMANCSLYRSCGDCLLARDPYCAWSGSSCKHVSLYQPQLATRPWIQDIEGASAKDLCS-------------------ASSVVSPSFVPTGEKPCEQVQFQPNTVNTLACPLLSNLATRLWLRNGAPVNASASCHVLPTGDLLLVGTQQ-LGEFQCWSLEEGFQQLVASYCPEVVEDGVADQTDEGGSVPVIIS---TSRVSAPAGGKASWGADRSYWKEFLVMCTLFVLAVLLPVLFLLYRHRNSMKVFLKQGECASVHPKTCPVVLPPETRPLNGLGPPSTPLDHRGYQSLSD------SPPGSRVFTESEK----RPLS---IQDSFVEVSPVCPRPRVRLGSEIRDSVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G4M4-1", "uniprot_id": "A0AC58G4M4_DANRE", "id": "A0AC58G4M4-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------MATKCKVQWKISMENTDSVWLLFWSIWIVLAGVLQSTMASEDDVTARISFTYNAEGRSVSGFSVNGVYNYSALLLSPDENKIYVGARENIFSLSLDN-ISVTHLQKTLTWSTPETKRGECIFKGKDPQTDCFNYIKILLRLNSTHLFVCGTYAFSPICTYINISSFSLEADEKGEPIMEDGRGRCPFNPEYRSTAITVDGELYTATVSNFQGNEPSIYRSLGSGTPLKTENSLNWLQDPAFVGSAHITGSDSER--NDDQIYFFFSETGKEFDFFDNTIVSRIARVCKEDQGGERVLQKKWTTFLKAQLLCSLPDDGFPFNIIQDVYVLPAKRK--KNTLLYAVFASQWSKGLAGSSAVCVFSMDQVDRAFTGRYKEVNRETQQWYTYTQSVPEPRPGMCITNASRQLGIDSSLDMPDKVLNFVKDHFLMDRPVRSQPVLFTHTVHYTQIAVHHVKGLHRAYDVMFIGTADGCLQKAVNVAGMMHIIEEIQLFSEQQPVQQIELDSAKGLLFVSSHSGIVQLPVANCSFHNNCGECVLARDPYCAWTGTHCTDVTLVPPQNQ---WLQDIEEADTSKCNSTMLRVDSGSSGLNGDTVDSSAAVSPRSFPNSQTSDCELIIIPANTLQLLPCNLRSNHAHRKWLYK---PNVSHFLFPSADGGLVVSGRAGSDEVFSCWSEERGFWQLLANYCVKAEPLSETTTKIGRKEAPFLIQSIASDILSEESEAHSAQHRIKTYGTELAVVCVLLAVCVLSFGLSVVYRHRGRMKEVLRGGEQAGGAQKS--TVHPGESLPLNAGAPPTSPSEHKSYQTLEENCSYIIAPAETNAPQKSEETQILKPTPQNGYKESHVEVSDISPRPRVRLGSEIRDSVV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * :* . .: : .***.. .:* * . *..: : **:***** * ..:****** :*:*. : : : * *.: :: :* ******: ** ******* *..:**:.*** ****:*:**: .*:* ** *. ::***:*****:*:::***:.*******.***.****:*:* ** * * ***.***********.**::. * .. :**:*********:**:**:******:**:** *:*******::**:********* ********::***:.* .. : :.**:*.**:*** :* : .**:***:*.:*::.* * **:********** *: ** **** ****::*: *:***::**:****:******* ***: :*: .:* ::***:* *** :***:*:**.** *:***.: :*****:*:*.. ****:: **: ***:.:****:**:*:****:: .**:*:*********.*: * :* *: * **** *.... . :: . : . *: : : .**:: *.* * ** * * *: : *.* . *.*:: * *.*** *.** **:*.** :. . . .*.:*. :. :* : .::: ::* .*: *:*.*: ..:: * .:**:*. ** .*: ** *. *: * * *: ***. .**::* :*:.**:*.: :.. ... :**: :* . ::*.**** :.****************", "identical_positions": 381, "similar_positions": 233, "identity": "38.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120503-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3U288-1", "uniprot_id": "ZN710_MOUSE", "id": "Q3U288-1", "name": "Zinc finger protein 710", "aln": "-----------------------------MEGFMDSGTQTDAVVVLSLAQAAVLGLVSENELFGATISAEAFYPDLGPELTGTAMGEPGPPGPDIYQLACNGRALEEPPEEEVLEVEAAFEKHTR---RKTRPPVR---LVPKVKFEKAEEEEEQEVYEVS--VPGDDK---DPGPAEAPAEVASSGCEALVQSSAVKMIDLS--AFSRKPRTLRHLPRTPRPELDMAPFDPPFPDPARDG-FPEPSMALPGPETLPTECSFEPPHLAPLSNPEPPNMTSTTELVKPEQGFVWQESSEFEADTAGSTVERHKKAQLDRLDINVQIDDSYLVEAGDRQKRWQCRMCEKSYTSKYNLVTHILGHNGIKPHSCPHCSKLFKQPSHLQTHLLTHQGTRPHKCQVCHKAFTQTSHLKRHMLLHSEVKPYSCHFCGRGFAYPSELKAHEVKHESGRCH-----VCVECGLDFSTLTQLKRHLASHQGPTLYQCLECDKSFHYRSQLQNHMLKHQN---VRPFVCTECG-MEFSQIHHLKQHSLTHK----------GVKEFKCEVCGREFTLQANMKRHMLIHTSVRPYQCHICFKTFVQKQTLKTHMIVHSPVKPFKCKVCGKSFNRMYNLLGHMHLHAGSKPFKCPY--CSSKFNLKGNLSRHMKVKHGVMDISLDSQDPMMELAGPDPSELDNHQEMEDFEENAYTYSSVDSSAEASTLTEQAMKEMAYYNVL---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6G6X3-1", "uniprot_id": "A0A8I6G6X3_RAT", "id": "A0A8I6G6X3-1", "name": "Zinc finger protein 710", "aln": "-----------------------------MEGFMDSGTQTDAVVVLSLAQAAVLGLVSENELFGATISAEAFYPDLGPELSGTAMGEPGPPGPDIYQLACNGQALEEPPEEEVLEVEAAFEKHTR---RKTRPPVR---LVPKVKFEKAEDEEEQEVYEVS--VPGDDK---DPGPAEAPEEAASGGCEALVQSSAVKMIDLS--AFSRKPRTLRHLPRTPRPELDTAPFDPPFPDPARDG-FLEPSMALPGSETLPTECSFEPPHLAPLSNPEPPNMTS-TELVKPEQGFVWQESSEFEADTAGSTVERHKKAQLDRLDINVQIDDSYLVEAGDRQKRWQCRMCEKSYTSKYNLVTHILGHNGIKPHSCPHCSKLFKQPSHLQTHLLTHQGTRPHKCQVCHKAFTQTSHLKRHMLLHSEVKPYSCHFCGRGFAYPSELKAHEVKHESGRCH-----VCVECGLDFSTLTQLKRHLASHQGPTLYQCLECDKSFHYRSQLQNHMLKHQN---VRPFVCTECG-MEFSQIHHLKQHSLTHK----------GVKEFKCEVCGREFTLQANMKRHMLIHTSVRPYQCHICFKTFVQKQTLKTHMIVHSPVKPFKCKVCGKSFNRMYNLLGHMHLHAGSKPFKCPY--CSSKFNLKGNLSRHMKVKHGVMDISLDSQDPMMELAGPDPSELDNHQEMEDFEENAYTYSSVDGSTEASALTEQAMKEMAYYNVL---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8N1W2-1", "uniprot_id": "ZN710_HUMAN", "id": "Q8N1W2-1", "name": "Zinc finger protein 710", "aln": "-----------------------------MEGFMDSGTQTDAVVVLSLAQAAVLGLVSENELFGATISAEAFYPDLGPELSGAAMGEPEPPGPDVYQLACNGRALEEPAEEEVLEVEAACEKHTR---RKTRPPVR---LVPKVKFEKVE-EEEQEVYEVS--VPGDDK---DAGPAEAPAEAASGGCDALVQSSAVKMIDLS--AFSRKPRTLRHLPRTPRPELNVAPYDPHFPAPARDG-FPEPSMALPGPEALPTECGFEPPHLAPLSDPEAPSMES-PEPVKPEQGFVWQEASEFEADTAGSTVERHKKAQLDRLDINVQIDDSYLVEAGDRQKRWQCRMCEKSYTSKYNLVTHILGHNGIKPHSCPHCSKLFKQPSHLQTHLLTHQGTRPHKCQVCHKAFTQTSHLKRHMLLHSEVKPYSCHFCGRGFAYPSELKAHEVKHESGRCH-----VCVECGLDFSTLTQLKRHLASHQGPTLYQCLECDKSFHYRSQLQNHMLKHQN---VRPFVCTECG-MEFSQIHHLKQHSLTHK----------GVKEFKCEVCGREFTLQANMKRHMLIHTSVRPYQCHICFKTFVQKQTLKTHMIVHSPVKPFKCKVCGKSFNRMYNLLGHMHLHAGSKPFKCPY--CSSKFNLKGNLSRHMKVKHGVMDIGLDSQDPMMELTGTDPSELDGQQEMEDFEENAYSYASVDSSAEASVLTEQAMKEMAYYNVL---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q8N3-1", "uniprot_id": "A0A8M9Q8N3_DANRE", "id": "A0A8M9Q8N3-1", "name": "Zinc finger protein 710", "aln": "MRSLKHLKPQTKKNVEEKTQRLVRCYSEAMHQQMDAGTQTDPVVVLSLAQAAVLGLISQNEVFGATIAPNGFYTGD-PKESPAPPGERMDYEYADQLIGANGDYLGENLGEDGHMHSSCAERRWQGQPENTKPPVGHQDMALHVKGESVTPGLPSCTHMMNNMVPREGMQMVDPTSYRVLPKSQSSNCSTTCVRDPKSTLSPPDPHLHSHSHGHNHAPHEVPTRNRGHTHEKGVDEVAEDRDNGRNGMGKAGNGEEQISSYFQANEVG----YEGGEMEGVGDFDENNDGMFWTEPVEGEAPRG---------RRIDRLDINIQINESYCVDVGEGLKRWKCRMCEKSYTSKYNLVTHILGHNGIKPHACPHCGKLFKQPSHLQTHLLTHQGTRPHKCTVCKKGFTQTSHLKRHMLQHTDVKPYSCRFCRRGFAYPSELRAHEVKHERGRCH-----VCSQCGMEFPTYAHLKRHQVSHQGPSTFQCSQCNKSFAYRSQLQNHLLKHQT---QRSFSCSQCG-LQFLQLHQLRQHSLTHKTNKPQTRATKGTKGFKCDVCAREFTLSANLKRHMLIHASVRPFQCHVCFKSFVQKQTLKTHMIVHLPVKPFKCKVCGKSFNRMYNLLGHMHLHAGSKPFKCAY--CSSKFNLKGNLSRHMKVKHG-MDVSPDGQD------GPTDMEPHEDYEDENFNFTAPENMENNDAPNLTKLSEVAIQELDYYNFGKDVGNYSTA", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P39933-1", "uniprot_id": "TF3A_YEAST", "id": "P39933-1", "name": "Transcription factor IIIA", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGGEVLNNEGMPLAELKQETIPISRSESSESLNSLTSTRSSSSNRPKTYFCDYDG---------------------------------------------------CDKAFTRPSILTEHQLSVHQGLRAFQCDKCAKSFVKKSHLERHLYTHSDTKPFQCSYCGKGVTTRQQLKRHEVTHTKSFICPEEGCNLRFYKHPQLRAHILS-VHLHKLTCPHCNKSFQRPYRLRNHISKHHDPEVENPYQCTFAGCCKEFRIWSQLQSHIKNDHP--KLKCPICSKPCVGENGLQMHMIIHDDSLVTKNWKCHICPDMSFSRKHDLLTHYGSIH----------TEEDIPLELKYKISDIQQLVQDHGVQLGNSK-HSNEQDEEKISNRLRKRRKLTENNNVEFLQNEVDLEKRLESGENGLNLLLNTVGRKYRCFYNNCSRTFKTKEKYEKHID-KHKVHELKLKILQ-----------EKEENKTLVDQNHKEPFIIQKETQSAGDK------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. . :.. . .. . :: *: . .* .: :.. : : ::* * **:..* :* *: *.. **. *.:*.* .. .:*: * :** : *: * : .:*: *:* .:: :* .* :.* * .*: * **. . . . * :* ::*: * ..: :* *.*. .. ** *:: *: : : * * :.* : *.* * : : : : :: : :. :: * : . : .. . :.: :: : :: : *: :: :* :. . : :: *:: .: ::* * ** .*: * : .:*:. ** :: . : * . . : : . . : . ", "identical_positions": 63, "similar_positions": 144, "identity": "8.53%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120507-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P85845-1", "uniprot_id": "FSCN1_RAT", "id": "P85845-1", "name": "Fascin", "aln": "MTAN----GTAEAVQIQ---------FGLISCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAVCLRSHLGPYLAADKDGNVTCEREVPDGDCRFLVVAHDDG--RWSLQSEAHRRYFGGTEDRLSCFAQSVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLAFQDQ---RYSVQTSDHRFLRHDGRLVARPEPATGFTLEFRSGKVAFRDCEGRYLAPSGPSGTLKAGKATKVGKDELFALEQSCAQVVLQAA-NERNVSTRQGMDLSANQDEETDQETFQLEIDRDTRKCAFRTHTGKYWTLTATGGVQSTASTKNASCYFDIEWC-ERRITLRASNGKFVTAKKNGQLAATVETAGDSELFLMKLINRPIIVFRGEHGFIGCRK-VTGTLDANRSSYDVFQLEFNDG-AYNIKDSTGKYWTVGSDSSVTSSSDTPVDFFLEFCDYNKVALKVG-GRYLKGDHAGVLKACAETIDPATLWEY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q61553-1", "uniprot_id": "FSCN1_MOUSE", "id": "Q61553-1", "name": "Fascin", "aln": "MTAN----GTAEAVQIQ---------FGLISCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAVCLRSHLGRYLAADKDGNVTCEREVPDGDCRFLVVAHDDG--RWSLQSEAHRRYFGGTEDRLSCFAQSVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLAFQDQ---RYSVQTSDHRFLRHDGRLVARPEPATGFTLEFRSGKVAFRDCEGRYLAPSGPSGTLKAGKATKVGKDELFALEQSCAQVVLQAA-NERNVSTRQGMDLSANQDEETDQETFQLEIDRDTRKCAFRTHTGKYWTLTATGGVQSTASTKNASCYFDIEWC-DRRITLRASNGKFVTAKKNGQLAASVETAGDSELFLMKLINRPIIVFRGEHGFIGCRK-VTGTLDANRSSYDVFQLEFNDG-AYNIKDSTGKYWTVGSDSSVTSSSDTPVDFFLEFCDYNKVALKVG-GRYLKGDHAGVLKACAETIDPASLWEY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q16658-1", "uniprot_id": "FSCN1_HUMAN", "id": "Q16658-1", "name": "Fascin", "aln": "MTAN----GTAEAVQIQ---------FGLINCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAVCLRSHLGRYLAADKDGNVTCEREVPGPDCRFLIVAHDDG--RWSLQSEAHRRYFGGTEDRLSCFAQTVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLAFQDQ---RYSVQTADHRFLRHDGRLVARPEPATGYTLEFRSGKVAFRDCEGRYLAPSGPSGTLKAGKATKVGKDELFALEQSCAQVVLQAA-NERNVSTRQGMDLSANQDEETDQETFQLEIDRDTKKCAFRTHTGKYWTLTATGGVQSTASSKNASCYFDIEWR-DRRITLRASNGKFVTSKKNGQLAASVETAGDSELFLMKLINRPIIVFRGEHGFIGCRK-VTGTLDANRSSYDVFQLEFNDG-AYNIKDSTGKYWTVGSDSAVTSSGDTPVDFFFEFCDYNKVAIKVG-GRYLKGDHAGVLKASAETVDPASLWEY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0A0MPL5-1", "uniprot_id": "A0A0A0MPL5_DANRE", "id": "A0A0A0MPL5-1", "name": "Fascin", "aln": "MSSE----GIGETLVIR---------FGLINADNKYLTAEMFGFKINASASSMKKKQVWTLEQSGDHGDSNAVFIKSHLGRYLASDKDGKVTADSEQPGPDCRFLVIAHDDG--RWSLQSEPHARYLGGTEDRIACFAQSISPAEKWNVHLAVHPQVNVYSIARKRYAHLCAD-RNELAVDRDVPWGVDSLLTLVYLDH---RYHLQTADNRFLSCGGTLTAKPDRDTGFTLEFRAGKVAFRDATGKYIAPTGPTGTMKSGRSARVGKDELFVLEQSHGQVVLTAS-NDRNISMRQGVDLSANQDEESDQEVFQMEMDRESKRCAFRSFNGRYWSLTSSGAIQCSALTKSPSCFFDLEWK-GSKVALKASNGKYLAAKKNGQLAAAVDSAGEQEEFVLKLINRPLIVLRGEHGFIGCRKQGTGTLDSNRSSYDVFQLEYNNN-AYSLRDSVGKYWTVESDGSVISSGAAPVYFHFEFCDFNKVAIKTKEGKYLKGDHAGVLKASAQGIADATLWEY", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q24524-1", "uniprot_id": "SING_DROME", "id": "Q24524-1", "name": "Protein singed", "aln": "MNGQGCELGHSNGDIISQNQQKGWWTIGLINGQHKYMTAETFGFKLNANGASLKKKQLWTLE--PSNTGESIIYLRSHLNKYLSVDQFGNVLCESDERDAGSRFQISISEDGSGRWALKNESRGYFLGGTPDKLVCTAKTPGASEFWTVHLAARPQVNLRSIGRKRFAHLSES-QDEIHVDANIPWGEDTLFTLEFRAEEGGRYALHTCNNKYLNANGKLQVVCNEDCLFSAEYHGGHLALRDRQGQYLSPIGSKAVLKS-RSSSVTRDELFSLEDSLPQASFIAGLNLRYVSVKQGVDVTANQDEVGENETFQLEYDWSAHRWALRTTQDRYWCLSAGGGIQATGNRRCADALFELIWHGDGSLSFRANNGKFLATKRSGHLFATSESIEEIAKFYFYLINRPILVLKCEQGFVGYRTPGNLKLECNKATYETILVERAQKGLVHLKAHSGKYWRIEGESISVDADAPSDGFFLELREPTRICIRSQQGKYLGATKNGAFKLLDDGTDSATQWEF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*..: * .: * :***. :**:*** ****:**..:*:****:**** .. .. : ::***. **: *: *:* .: : . ..** : :** **:*:.*.: ::*** *:: * *:: ..:* *.**:* :****: *: ***:***. :*: ** ::*** *:*:** : . ** ::*.::::* .* * . : :: *::.*::*:** *:*::* *....:*: ::: * :**** **:* *. : *. * * :* :**:*::***** ::*.**:* * .::: *:*: .:** *:: *.:*.:. : ... *:: * ::::*.***::::*:.*:* *: :: : * : *****::*:: *:**:* *. . .*:.*:::*:.: :* : :: **** : .:. .:. .. *.:*: : .::.:: *:** . : *.:* : *: **:", "identical_positions": 163, "similar_positions": 193, "identity": "31.59%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120508-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9C0H2-1", "uniprot_id": "TTYH3_HUMAN", "id": "Q9C0H2-1", "name": "Protein tweety homolog 3", "aln": "-----MAGVSYAAPWWVSLLHRLPHFDLSWEATSSQFRPEDTDYQQ----------------ALLLLGAAALACLALDLLFLLFYSFWLCCRRRKSEEHLDADCCCTAWCVIIATLVCSAGIAVGFYGNGETSDGIHRATYSLRHANRTVAGVQDRVWDTAVGLNHTAEPSLQTLERQLAGRPEPLRAVQRLQGLLETLLG------YTAAIPFWRNT-------AVSLEVLAEQVDLYDWYRWLGYLGLLLLDVIICLLVLVGLIRSSKGILVGVCLLGVLALVISWGALGLELAVSVGSSDFCVDPDAYVTKMVEEYSVLSGDILQYYLACSPRAANPFQQKLSGSHKALVEMQDVVAELLRT--VPWEQPATKDPLLRVQEVLNGTEVNLQHLTALVDCRSLHLDYVQALTGFCYDGVEGLIYLALFSFVTALMFSSIVCSVPHTWQQKRGPDEDGEEE------------------------------------------AAPGPRQAHDSLYRVHMPSLYSCG------------------SSYGSETSIPAAAHTVSNAPVTEYMSQNANFQNPRCENTPLIGRESPPPS-YTSSMRAKYLATSQPRPDSSGS-H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q6P5F7-1", "uniprot_id": "TTYH3_MOUSE", "id": "Q6P5F7-1", "name": "Protein tweety homolog 3", "aln": "-----MAGVSYAAPWWVSLLHRLPHFDLRWEATSSQFRPEDADYQQ----------------ALLLLGATALACLALDLLFLLFYSFWLCCRRRKTDEHLDADCCCTAWCVIITTLVCSAGIAVGFYGNGETSDGIHRATYSLRHANRTVAGVQDRVWDTAAALNRTAEPNLQSLERQLAGRQEPLRAVQRLQTLLGTLLG------YTAAIPFWRNP-------GVSLEVLAEQVDLYDWYRWLGYLGLLLLDVIICLLVLVGLIRSSKGILVGVCLLGVLALVISWGALGLELAVSVGSSDFCVDPDTFVTKMVEEHSVLSGDILQYYLACSPRATNPFQQKLSGSHKALVEMQDVVAELLRN--VPREHPATKDPLLRVQEVLNGTEVNLQHLTALVDCRSLHLDYVQALTGFCYDGVEGLIYLALFSFVTALMFSSIVCSIPHTWQQKRGPDDDGEEE------------------------------------------TAPGPRQAHDSLYRVHMPSLYSCG------------------SSYGSEASIPAAAHTVSNAPVTEYMSQNANFQNPRCENTPLIGRESPPPS-YTSSMRAKYLATSQPRPDSSGSGH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0G2K0W3-1", "uniprot_id": "A0A0G2K0W3_RAT", "id": "A0A0G2K0W3-1", "name": "Protein tweety homolog", "aln": "-----MAGVSYAAPWWVSLLHRLPHFDLRWEATSSQFRPEDADYQQ----------------ALLLLGAAALACLALDLLFLLFYSFWLCCRRRKTDEHLDADCCCTAWCVIIATLVCSAGIAVGFYGNGETSDGVHRATYSLRHANRTVAGVQDRVWDTAAALNRTAEPNLQSLEKQLAGRPEPLRAVQRLQTLLGTLLG------YTAAIPFWRNP-------GVSLEVLAEQVDLYDWYRWLGYLGLLLLDVIICLLVLVGLIRSSKGILVGVCLLGVLALVISWGALGLELAVSVGSSDFCIDPDTFVTKMVEEYSVLSGDILQYYLACSPRATNPFQQKLSGSHKALVEMQDVVAELLKN--VPREHPATKDPLLRVQEVLNGTEVNLQHLTALVDCRSLHLDYVQALTGFCYDGVEGLIYLALFSFVTALMFSSIVCSIPHTWQQKRGADEDGEEE------------------------------------------TAPGPRQAHDSLYRVHMPSLYSCG------------------SSYGSEASIPAAAHTVSNAPVTEYMSQNANFQNPRCENTPLIGRESPPPSRYLAALDSGSHAGWQFKPMDSARTLW----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M3AY88-1", "uniprot_id": "A0A8M3AY88_DANRE", "id": "A0A8M3AY88-1", "name": "Protein tweety homolog", "aln": "----MAAVVNYSPPWWVNLLHRLPHFNLQFEQTSSDFRPEESSYQQ----------------SLLLLGGVALACLALDLLFLLIYSCWLCCRRKKSDEQPNADCCCTAWCVIIATLVCSAGIAVGFYGNGETCDGVSRLTYSLRHANRTVSGVHRLVSESTSAQSQTVDENLRILKEQYAKHTDYLSIIQKLQDQRSELVR------QMADIPFWSNL-------GVSLEDLATQIELYDWYRWLGYLGLLLFDVLICLLVLFGLIRNSKGTLIGVCILGVLALVISWSSLGLELTVSSGFSDFCAAPDMYITKVSEEYTIIKKDILPYYLTCDVGQANPFQQKLSGSHKALVEMQDDVSELLRS--AVREYPKTKGNLEQIQRGLNTTEAGLHQLTALVDCRSLHMDYVQALTGVCYDGLEGLIYLVLFSFITALMFTSVICSVPHTWHGKRPEEDSEEES------------------------------------------VAPGGRQNHDNLYRVHMPSLYSCG------------------SSYGSETSIPAGAHTVSNAPVTEYMTQNANFQNPRCENTPLIGRESPPPSLYLTSTDSNSRHSWQLKPSESSRSFW----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9U6L4-1", "uniprot_id": "TTY1_DROME", "id": "Q9U6L4-1", "name": "Protein tweety", "aln": "MGDYHEFTDQYKVPVIAKLLHALPHYNITFHKINSTFRPNDEIYLE----------------SLGILGSVPAALLIVSLLGLLFYLMTRCCDRKPRPAHS---ITSLKVALSIVTVMCCAAIGLGLYGNDDLHNGLLEVLTAGRKVDNLVTTIRNQTHILENTLTNRIRPQLVELADIFDQPVSNQTALSKLFVSLNIVQGNVTLATNAASDIRRPLM-------GISMTHFLTRGDQWELIRWPGTVATLALLLVLCAVLLVGVARHSRCALILFSVCGLLAVTGSWLMSGLYLSSSVAVGDLCISPADFLVSTAPRD--LPTNVLLHYTQCEPGHTNPFTQRLRESQNSLNNARSAMATVMKISLVLFKSSGLQPKLGAVNADLNSSERLLTQLTALVDCKAVHHNFLAAARGLCEGGLLGLVLMLIASFIAAILLTIMVWVDSHTWIYIRKRNDYAQVDEPSYISHPAPQNHQQMMNAARTLPRNHNGHFSPPVISGSHTLQHPSKRQQHEMMAHAHIQQNMRAMGTHTLGRLPSHNHSPTHMTGPNNAAAVAAAANAAANMPPTTQAAQQQQQQQAQQQQQQAQQQLGGPQPIYCHHPHQHPHPHPHQHPHSHSAAAVAAAVQHQHAIYHQQQAQQYGTYTTAAHHAPHHLGPGQSQIYQQIPAHLAPQLAANGNPHSIYQPLVAVSQGSIYVSNMATMRRQNSQGGPQIPAHQHPPSLHQQQQQPPPPSQQQQQLHQLKSPQQHQQQLQQHQQQQQQQHHQQQHHQQQHQQQQQQHHQQQQPNESDVVPISTAMDTAIYDRDKQIYKCSTLRQGGKFDPKYKPSILNCPLPEIPKDAEQPKVESIYEQRQQAHHQNYSKTLQRPPMMLPPQMKAIPPPRIGTPTSPPPPVAQPLNESNGGVPSGLQNGGAVVGGGGANANEDTSLPPPPLEAQTEATKARMGAGPAANGKVLHNGGGGGSVGGGGGGAVDDDDDLPPPPPAITDESNYAVTEL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W5A5-1", "uniprot_id": "TTYH2_DROME", "id": "Q9W5A5-1", "name": "Protein movement modulator", "aln": "---------MEQPSILVKILHSIPHVNYTFRRVNDTFNPDSDVYLEPTNNKLQCQQKGIELQSLVILASIPAGLLIGSLLGLLLYLLTRCCDRRQRKPSAQR---CQSCSLVIITLMTCAAIGLGLYGNDDFHNGLLQAFGSGKSVEGLVLTLKRQTESIKHDLETRMAG--HKVEQLVEKPHYNQTVVMLLIETSRLVTENTSRAVASLDSMVHYFMKAKGSENDTSLMGLLQLGEFYESIRWPATLAFLTVLLLLCTVLVIGVARRSRCTLIFFSVSGLFCIIICWLLAGVYLASSVAAGDFCMRPHDYMCRQVGMR-----SPYVDFLNCG-TPRNRFILRLNESRDLVDRARESVEHMQRMSQETYPHIDIQRTLNAMDNDLEITLRNLTTLSATLDRRTIDMHYEEALRGLCGGGLLGLSLMMVAGLLTSFLLTILVYADSHAWIYLTKRPTLDADKSE----------------------------------------TAPLFPASNAPSASISPTAPLSTG--------------TINRTLLHHQQASSGGGSGTLPGSGGGAGAGGGVGANGHNGVGPYRNGSAGLRQGLASPSSQSSHTSSTATYNNGTTSYHNSHQQHNNHLYSNHYSHSNNHYNNTQHRTNPAAGAVAAAVGVVSSGQRSP------SPPPVYDLVHGTRSGHHTLG--------------RLPSHHQQSATYLPGPNNGKYATLSKQCKTLESNDFY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ..:** :** : :. .. *.*:. * : :* :*.. . . * .** **:* ** *: . .: * *:: .*.*.:*:***.: :*: . : : .: * :: . : : * : *: : : :: ** . :. * . :::* :::.*: * *: *: ..: *::.: .* *: *: * . .*:* * :: . : * * * :* *:. : . :. : : : : * :: *: : * *:* :* :::. .: * *.* .*: ** : : .:::::::: :: .*:* . * : : : .... . . : : : . . ", "identical_positions": 66, "similar_positions": 140, "identity": "6.61%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120508-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JYJ5-1", "uniprot_id": "A0A0G2JYJ5_RAT", "id": "A0A0G2JYJ5-1", "name": "", "aln": "MFSAGAESLLHQAREIQDEELQRFCSRVTKLLQ-EAPGPATVDALQRLFLIVSSTKYPRRLEKACVDLLQTTLCLPTSPEQLQVLCAAILREMSPFNDLTLSCDHTQNTRQLSLVASVLLAQGDRNGEIRQVSQRIFKILENRQPEGPSVRPLLPVLSKVIGLAPGILVEDQTNLLSKRLVDWLRYASIQQGLPYS-GGFFSTPRTRQPGPITEVDGAVASDFFTVLSTGQHFTEDQWVNMQAFSMLRKWLLHSGPEDPGSPD--------------ADDKSELEGSMLSVLSAASTASRLLPPRERLREVAFEYCQRLLEQSNRRALRKGDSDLQKACLVEAVLVLDVLCRQDPSFLYRTLSCLKPLHRRLGEDPGSERALVPLAQFFLNHGEAAAMDAEAIYAQLLGSLPSERFHSPTLAFEVIHFCTHNLALFDPHFLSLLRLSFPNLFKFLAWNSPPLTAEFVVLLPALVDAGTAVEMLHALLDLPCLTAALDLQLR-STQTPSERPLWDVS-LRVPSCLEAFQDPQFQGLFRHLLRTKASG--STERLTPLHQVLKPMASCARVAQCVEAIPVLLQAFFSAVTQTADGPLINQLALLLLERSDSLYPVPQYEARVHRVLSSQLLVLCKLKPSLVVELSRELLEFVGSVSSIRSRASMFTCVVWAIGEYLSVTCDKRCTAEQINKFFEALEALLFEVTQSRPSADLPCCPPELVTALMTTLTKLASRSQDLIPRVSLFLSKMRTLAQNPATSSMHSEEDTESIRIRATELLTLLKMPSVAQFVFTPTVGVCQPRYHQDTNVALPLALRTVSRLVEKEAGLLPG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U829-1", "uniprot_id": "AP5Z1_MOUSE", "id": "Q3U829-1", "name": "AP-5 complex subunit zeta-1", "aln": "MFSAGAESLLHQAREIQDEELRRFCSRVTKLLQ-EAPGPATVDALQRLFLIVSATKYPRRLEKMCVDLLQTTLCLPASPEQLQVLCAAILREMSPFNDLALSCDHTPNTRQLSLVASVLLAQGDRKGEIRCVSQRIFKILENRQPEGPSVRPLLPILSKVIGLAPGILMEDQTNLLSKRLVDWLRYASIQQGLPYS-GGFFSTPRTRQPGPITEVDGAVASDFFTVLSTGQHFTEDQWVNMQAFSMLRKWLLHSGPEDPCSPD--------------ADDKSELEGSTLSVLSAASTASRLLPPRERLREVAFEYCQRLLEQSNRRALRKGDSDLQKACLVEAVSVLDVLCRQDPSFLYRTLSCLKALHRRLGEDPGSERALVPLAQFFLNHGEAAAMDAEAVYGQLLRGLPSERFHSPTLAFEVIHFCTHNLALFDSHFLSLLRLSFPSLFKFLAWNSPPLTAEFVVLLPALVDAGTAVEMLHALLDLPCLTAALDLQLR-STQTPSERLLWDIS-LRVPSCLEAFQDPQFQGLFRHLLRTKASG--STERLTPLHQVLKPMASCARVTQCAEAVPVLLQAFFSAVTQTADGALINQLALLLLERSDSLYPVPQYEARVHGVLSSQLLVLCKLKPSLVVELSRELLEFVGSVSSIHSRASVFTCVVWAIGEYLSVTWDKRCTAEQINKFFEALEALLFEVTQSRPLADLPCCPPEVVTALMTTLTKLASRSQDLIPRVSLFLSKMRTLAQNPATSSVHSEEGAESIRTRASELLTLLKMPSVAQFVFTPPAGVCQPRYHRDTNVALPLALRTVSRLVEKEAGLLPG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43299-1", "uniprot_id": "AP5Z1_HUMAN", "id": "O43299-1", "name": "AP-5 complex subunit zeta-1", "aln": "MFSAGAESLLHQAREIQDEELKKFCSRICKLLQAEDLGPDTLDSLQRLFLIISATKYSRRLEKTCVDLLQATLGLPACPEQLQVLCAAILREMSPSDSLSLAWDHTQNSRQLSLVASVLLAQGDRNEEVRAVGQGVLRALESRQPEGPSLRHLLPVMAKVVVLSPGTLQEDQATLLSKRLVDWLRYASLQQGLPHS-GGFFSTPRARQPGPVTEVDGAVATDFFTVLSSGHRFTDDQWLNVQAFSMLRAWLLHSGPEGPGTLD--------------TDDRSEQEGSTLSVISATSSAGRLLPPRERLREVAFEYCQRLIEQSNRRALRKGDSDLQKACLVEAVLVLDVLCRQDPSFLYRSLSCLKALHGRVRGDPASVRVLLPLAHFFLSHGEAAAVDSEAVYQHLFTRIPVEQFHSPMLAFEFIQFCRDNLHLFSGH-LSTLRLSFPNLFKFLAWNSPPLTSEFVALLPALVDAGTALEMLHALLDLPCLTAVLDLQLR-SAPAASERPLWDTS-LRAPSCLEAFRDPQFQGLFQYLLRPKASG--ATERLAPLHQLLQPMAGCARVAQCAQAVPTLLQAFFSAVTQVADGSLINQLALLLLGRSDSLYPAPGYAAGVHSVLSSQFLALCTLKPSLVVELARDLLEFLGSVNGLCSRASLVTSVVWAIGEYLSVTYDRRCTVEQINKFFEALEALLFEVTQCRPSAALPRCPPQVVTVLMTTLTKLASRSQDLIPRASLLLSKMRTLAHSPATSSTHSEEGAEAIRTRATELLTLLKMPSVAQFVLTPSTEVCSPRYHRDANTALPLALRTVSRLVEREAGLMPG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M6YX82-1", "uniprot_id": "A0A8M6YX82_DANRE", "id": "A0A8M6YX82-1", "name": "", "aln": "MYAAATESLIKQAREIKEEELQRFCGRVYKLLHSKDVIGEAVDSLQRLHLIVSATKYARELPSDLLMKLQTLLRSSSCPEQLQFLSSSIIRESFPPSVHSLSSDLSQDSRIFSCVAAVVLAQAGGKEDVMPLFHHLMKSFESRLSDGQIPKHALPILSSMITTYSEILTDDQVNLVSRKLVDWLRYASMQQGASMSSGGFFSAPRTRQPAPLTEVDGVVTGDFFTVLCVGQSYTEDQWMNMYAFSMIKSWLLTYDTEGTTNTESALLKRAQIIQLQHQDDRSEVDSSVMSMVSATSSSSRLLPPKERLREKAFEYCQRLIEQSDRKALKRTDTELQKACIVESVSIMDIICGEDPSYVYRAFPCIKALYGRLNGDFAYARTLLPIAQFYLNHSETAAVDSEAVFCQLFGHCPAEQFNEPMLAFEFVQFCLLNSSVLQDR-VANYRQSFPNLLKFLAWNSSGLIAEFVELLPSLVAPDTAIELLHTILDLPCLAAALDLQQRSSCYQASDRTTWDQQGAKVAACLEAFRQPSYRGLFLYILRPEAGTGDTIDRLKELHQILADMAECPRVVQCAQIVPVLLHVYFNTVTEKADEKMMNQLLLVLLERCSLLYNIKTFHVEVQRAFSTHLQALCKHHPPLIVDQSREILEFAGSPTNIYSKEDFYTHVVWVIGEYLSVSYDPRCRVELITSFFECLEAVLFEITQVRQSASPPSFSPRLITVLMTTLAKLATRSQDLIPRASLFLSKMRTFARSAPVTACYSEEDTEEIITRAHELINLLKLPNVAQFVLAPSAGADGPRWHRDTNASLPQAMRTVSGLLHKHSSFLPA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*::*.:***::*****::***::**.*: ***: : ::*:****.**:*:***.*.* . : **: * .:.*****.*.::*:** * . :*: * : ::* :* **:*:***.. : :: : : ::: :*.* .:* : **:::.:: . * :**..*:*::*********:*** . * *****:**:***.*:*****.*: ******. *: :*:***:*: ****:: *** ..*.. . : **:** :.* :*::**:*::.*****:***** ********:***:*:**:: *::*****:**:* ::*::* :***::**::.*:*.*: *: * . *.*:*:*:*:*.*.*:**:*:**:: :*: * *:*:.* ****.::** * ::. : :: * ***.*:*******. * :*** ***:** ..**:*:**::******:*.**** * * .*:* ** . :..:*****::*.::*** ::**.:*. : :** ***:* ** *.**.**.: :*.**:.:*.:**: ** ::*** *:** *.. ** : . *: .:*::: .**. :*.*:*: :*::*** ** ..: *: .. * ***.*******: * ** .* *..***.***:***:** * * * .*.::*.*****:***:********.**:******:*:....:: :***.:* * ** **:.***:*.*****::*.. . **:*:*:*.:** *:**** *:.:.:.::*.", "identical_positions": 383, "similar_positions": 278, "identity": "46.31%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120508-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43115-1", "uniprot_id": "PE2R3_HUMAN", "id": "P43115-1", "name": "Prostaglandin E2 receptor EP3 subtype", "aln": "MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQTSVEHCKTH-----TEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIR-----YHTNNYASSSTSLPCQCSSTLMWSDHLER----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P30557-1", "uniprot_id": "PE2R3_MOUSE", "id": "P30557-1", "name": "Prostaglandin E2 receptor EP3 subtype", "aln": "--------------------MASMWAPEHSAEAHSNLS---STTDDCGSVSVAFPITMMVTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLSSLLVASAMAVERALAIRAPHWYASHMKTRAT-PVLLGVWLSVLAFALLPVLGVGRYSVQWPGTWCFISTGPAGNETDPAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKAAVSQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQ-----MGKEKECNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIR-----DHTN-YASSSTSLPCPGSSALMWSDQLER----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FD73-1", "uniprot_id": "E7FD73_DANRE", "id": "E7FD73-1", "name": "Prostaglandin E2 receptor EP3 subtype", "aln": "------MASKCKSSTVLLQNLTAGIMPDSNISKSSQDS--PGRSAGCGSVSVFFPITMMVTGMVGNSLAMLLVYSAYRKKENKRKRSFLLCIGSLALTDLFGQLLTSPIVISVYRADMKWDRVDPSKTLCAFFGVCMTTFGLCPLFLASAMAIERALAIIAPHWYSHYMKTSVTKQVLVIIWCLVLLFALLPIAGVGEYTLQWPGTWCFINTG-------DKDVTGNTFFATTFAALGIFSLLVTLSCNVVTIRALVTRCKTKSSSTQSSKQWERLTTETVIQLMGIMCVLLTCWSPLLVLMLKMILTHTSSHHCYSAGSLSPQELQKDCNFFLTAIRLASLNQILDPWVYLLLREILLRKFCQVASAVSKCSLDVQKQTQCPLDVQNKKAIQNDDVHKQSLNVENSILNVGCEEQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. *: . . .: : . .****** *****::**:***:****** :**::*.***:******* ******.*****:*:** ** :. :*:::*** **:***: **.***..*::*****:****** *****: :*** .* **: :* ** *****: ***.*::*********.** *. **::** **:::* **::**:.**:***:**::*:: :*** ** *:****.********** .******::*****:.: * .:* : :*:** ** *:******************:********: : .:. .* ..:: .* :: ", "identical_positions": 199, "similar_positions": 91, "identity": "47.84%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120510-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P35368-1", "uniprot_id": "ADA1B_HUMAN", "id": "P35368-1", "name": "Alpha-1B adrenergic receptor", "aln": "MNPDLDTGHNTSAPAHWGELKNANFTGPNQTSSNSTLP-QLDITRAISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFVRILGCQCRGRGRRRRRRRRRLGGCAYTYRPWTRGGSLERSQSRKDSLDDSGSCLSGSQRTLPSASPSPGYLGRGAPPPVELCAFPEWKAPGALLSLPAPEPPGRRGRHDSGPLFTFKLLTEPESPGTDGGASNGGCEAAADVANGQPGFKSNMPLAPGQF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P97717-1", "uniprot_id": "ADA1B_MOUSE", "id": "P97717-1", "name": "Alpha-1B adrenergic receptor", "aln": "MNPDLDTGHNTSAPAHWGELKDANFTGPNQTSSNSTLP-QLDVTRAISVG-CLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAIADLLLSFTDLPFSATLEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFMRILGCQCRG--GRRRRRRRRLGACAYTYRPWTRGGSLERSQSRKDSLDDSGSCMSGSQRTLPSASPSPGYLGRGTQPPVELCAFPEWK-PGALLSLP--EPPGRRGRLDSGPLFTFKLLGEPESPGTEGDASNGGCDTTTDLANGQPGFKSNMPLAPGHF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B692-1", "uniprot_id": "A0ACD6B692_DANRE", "id": "A0ACD6B692-1", "name": "", "aln": "MSSDTDHAANFLSNASS-ELSDVSNS---SSSGNGTAPSSFSLSRALPLGMVLGAFIVFAIVGNILVILSVVCNRHLRIPTNYFIINLAMADLLLSTTVLPVSATREILNYWVFGRIFCDIWAAVDVLCCTASIMSLCVISIDRYIGVRYPLQYPSIVTEKRALLAMLGVWVLAFVISIGPLLGWKEPPSEDDTVCLITEEPFYALFSSLGSFYIPLAVILAMYCRVYIVAKRTTKNLEAGVMKEHMDSNELTLRIHYK---GSQTQEDCTKGH-LRSSLTVKLLKFSREKKAAKTLGVVVGMFILCWLPFFLALPIGSFNTSLRPPETFFKVIFWLGYFNSCLNPIIYPCYSREFKQAFIRILRCQCQQ--------KKQQGWRAYNYR---------VPNANHVYSDTSSICMNGSLQTLAPSQPSPTLFSRVVGSRPASGLLPGWG-PCTSSSSSSLSGSPFPGMMRSGSQATSPCKSNRMALLFPNGQ-NGKREAEHGVISRHTPETTI--------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*..* * . * : * **.:.. : .:*.*.* * .:.::**:.:* *****:*************.****** ******:***:****** * **.**: *:*.***:********************:***.***********.****::**.::*:**:*.****: *************..:**. * :***********************.*********************** :*:******* * . .. :*** ***::***:*************:*************:***:**: ::*:**::.***:***************** *:***:**:*** ***: ::: * **.** .::.: * *. *:.** :**..:.*** :.* . . :* * * : * . . . * **. * : : .. ** :: .: . :. .: ", "identical_positions": 283, "similar_positions": 112, "identity": "54.32%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120510-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P01031-1", "uniprot_id": "CO5_HUMAN", "id": "P01031-1", "name": "Complement C5", "aln": "MGLLGILCFLIFLGKTWGQEQTYVISAPKIFRVGASENIVIQVYGYTEAFDATISIKSYPDK-KFSYSSGHVHLSSENKFQNSAILTIQPKQLPGGQNPVSYVYLEVVSKHFSKSKRMPITYDNGFLFIHTDKPVYTPDQSVKVRVYSLNDDLKPAKRETVLTFIDPEGSEVDMVEEIDHIGIIS-FPDFKIPSNPRYGMWTIKAKYKEDFSTTGTAYFEVKEYVLPHFSVSIEPEYNFIGYKNFKNFEITIKARYFYNKVVTEADVYITFGIREDLKDDQKEMMQTAMQNTMLINGIAQVTFDSETAVK---ELSYYSLEDLNNKYLYIAVTVIESTGGFSEEAEIPGIKYVLSPYKLNLVATPLFLKPGIPYPIKVQVKDSLDQLVGGVPVTLNAQTIDVNQETSDLD-----PSKSVTRVDDGVASFVLNLPSGVTVLEFNVKTDAPDLPEENQAREGYRAIAYSSLSQSYLYIDWTDNHKALLVGEHLNIIVTPKSPYIDKITHYNYLILSKGKIIHFGTREKFSDASYQSINIPVTQNMVPSSRLLVYYIVTGEQTAELVSDSVWLNIEEKCGNQLQVHLS----PDADAYSPGQTVSLNMATGMDSWVALAAVDSAVYGVQRGAKKPLERVFQFLE-KSDLGCGAGGGLNNANVFHLAGLTFLTNANADDSQENDEPCKEILRPRR---TLQKKIEEIAAKYKHSVVKKCCYDGACVN-NDETCEQRAARISLG-----------PRCIKAFTECCVVASQLRANISHKDMQLGRLHMKTLLPVSKPEIRSYFPESWLWEVHLVPR-RKQLQFALPDSLTTWEIQGVGISNTGICVADTVKAKVFKDVFLEMNIPYSVVRGEQIQLKGTVYNYRTSGMQFCVKMSAVEGICTSESPVIDHQGTKSSKCVRQKVEGSSSHLVTFTVLPLEIGLHNINFSLETWFGKEILVKTLRVVPEGVKRESYSGVTLDPRGIYGTISRRKEFPYRIPLDLVPKTEIKRILSVKGLLVGEILSAVLSQEGINILTHLPKGSAEAELMSVVPVFYVFHYLETGNHWNIFHSDPLIEKQKLKKKLKEGMLSIMSYRN-ADYSYSVWK--GGSASTWLTAFALRVLGQVNKYVEQNQNSICNSLLWLVENYQLDNGSFKENSQYQPIKLQGTLPVEARENSLYLTAFTVIGIRKAFDIC--PLVKIDTALIKADNFLLENTLPA----QSTFTLAISAYALSLGDKTHPQFRSIVSALKREALVKGNPPIYRFWKDNLQHKDSSVPNTGTARMVETTAYALLTSLNLKDINYVNPVIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLVKQLRLSMDIDVSYKHKG-ALHNYKMTDKNFLGRPVEVLLNDDLIVSTGFGSGLATVHVTTVVHKTSTSEEVCSFYLKIDTQDIEASHYRGYGNSDYKRIVACASYKPSREESSSGSSHAVMDISLPTGISANEEDLKALVEGVDQLFTDYQIKDGHVILQLNSIPSSDFLCVRFRIFELFEVGFLSPATFTVYEYHRPDKQCTMFYSTSNIKIQKVCEGAACKCVEADCGQMQEELDLTISAETRKQTACKPEIAYAYKVSITSITVENVFVKYKATLLDIYKTGEAVAEK-DSEITFIKKVTCTNAELVKGRQYLIMGKEALQIKYNFSFRYIYPLDSLTWIEYWPRDTTCS--SCQAFLANLDEFAEDIFLNGC------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P06684-1", "uniprot_id": "CO5_MOUSE", "id": "P06684-1", "name": "Complement C5", "aln": "MGLWGILCLLIFLDKTWGQEQTYVISAPKILRVGSSENVVIQVHGYTEAFDATLSLKSYPDK-KVTFSSGYVNLSPENKFQNAALLTLQPNQVPREESPVSHVYLEVVSKHFSKSKKIPITYNNGILFIHTDKPVYTPDQSVKIRVYSLGDDLKPAKRETVLTFIDPEGSEVDIVEENDYTGIIS-FPDFKIPSNPKYGVWTIKANYKKDFTTTGTAYFEIKEYVLPRFSVSIELERTFIGYKNFKNFEITVKARYFYNKVVPDAEVYAFFGLREDIKDEEKQMMHKATQAAKLVDGVAQISFDSETAVK---ELSYNSLEDLNNKYLYIAVTVTESSGGFSEEAEIPGVKYVLSPYTLNLVATPLFVKPGIPFSIKAQVKDSLEQAVGGVPVTLMAQTVDVNQETSDLE-----TKRSITHDTDGVAVFVLNLPSNVTVLKFEIRTDDPELPEENQASKEYEAVAYSSLSQSYIYIAWTENYKPMLVGEYLNIMVTPKSPYIDKITHYNYLILSKGKIVQYGTREKLFSSTYQNINIPVTQNMVPSARLLVYYIVTGEQTAELVADAVWINIEEKCGNQLQVHLS----PDEYVYSPGQTVSLDMVTEADSWVALSAVDRAVYKVQGNAKRAMQRVFQALDEKSDLGCGAGGGHDNADVFHLAGLTFLTNANADDSHYRDDSCKEILRSKRNLHLLRQKIEEQAAKYKHSVPKKCCYDGARVN-FYETCEERVARVTIG-----------PLCIRAFNECCTIANKIRKESPHKPVQLGRIHIKTLLPVMKADIRSYFPESWLWEIHRVPK-RKQLQVTLPDSLTTWEIQGIGISDNGICVADTLKAKVFKEVFLEMNIPYSVVRGEQIQLKGTVYNYMTSGTKFCVKMSAVEGICTSGSSAASLHTSRPSRCVFQRIEGSSSHLVTFTLLPLEIGLHSINFSLETSFGKDILVKTLRVVPEGVKRESYAGVILDPKGIRGIVNRRKEFPYRIPLDLVPKTKVERILSVKGLLVGEFLSTVLSKEGINILTHLPKGSAEAELMSIAPVFYVFHYLEAGNHWNIFYPDTLSKRQSLEKKIKQGVVSVMSYRN-ADYSYSMWK--GASASTWLTAFALRVLGQVAKYVKQDENSICNSLLWLVEKCQLENGSFKENSQYLPIKLQGTLPAEAQEKTLYLTAFSVIGIRKAVDIC--PTMKIHTALDKADSFLLENTLPS----KSTFTLAIVAYALSLGDRTHPRFRLIVSALRKEAFVKGDPPIYRYWRDTLKRPDSSVPSSGTAGMVETTAYALLASLKLKDMNYANPIIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLLKQIHLDMDINVAYKHEG-DFHKYKVTEKHFLGRPVEVSLNDDLVVSTGYSSGLATVYVKTVVHKISVSEEFCSFYLKIDTQDIEASSHFRLSDSGFKRIIACASYKPSKEESTSGSSHAVMDISLPTGIGANEEDLRALVEGVDQLLTDYQIKDGHVILQLNSIPSRDFLCVRFRIFELFQVGFLNPATFTVYEYHRPDKQCTMIYSISDTRLQKVCEGAACTCVEADCAQLQAEVDLAISADSRKEKACKPETAYAYKVRITSATEENVFVKYTATLLVTYKTGEAADE--NSEVTFIKKMSCTNANLVKGKQYLIMGKEVLQIKHNFSFKYIYPLDSSTWIEYWPTDTTCP--SCQAFVENLNNFAEDLFLNSCE-----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FCV2-1", "uniprot_id": "E7FCV2_DANRE", "id": "E7FCV2-1", "name": "", "aln": "MARLLLFCIFNLFVCFTVQENVYLITAPKVLRLDASETVVVQLFGFDQETTVHLHLKNTLAVGNKEYDYQSLKLNAANNYQASATLRILAKDFPKED---TSVYLQTISSAFTDNVKIPVTTVNGFLFIQTDKPLYTPEQEVQVRVYSLNEELRKSARTVTLTFQDPRGVKVEIIDMTDINGAKPLLPPFKIPLKPIYGIWKIVATYADNFETTATAEFEVKEYVLPSISVQIEPETNYISEENFDTFKLKISAKYVQGMPVKSANILLKFGY---STPEETVIIPSTYRSYMLYNGKMEVDLDIRSALSSKPDAPQFLNAMKENTFLYVEVLLQESTGGLSQEAVLSHVKFVETPFTLSIIATPPFIKPGLPYAMRVLVKDPLGEPVKDVSVTMRATATTVDNLSDNLKFLGHQDSVTVPSSKDGVAYFTCNIPANVKNAEFTFETEDASWS---QGPLTLKAESYVSVNHRYLYIDLPPESSVFEVGQYVDISVVFSYRDYLSLDTFSYQIISKGKVVKYDTVKRVSEKS-QSLNIKITPDMVPSARLLVYYVLYGEEKAELVADSTWIDVKAKCVKNLNLELSTLKLQDDYKPKDKLEIKVSSRSKGESLVAFSAVDTALFNLRTNKKDPLKKILQHVE-KSDLGCGKGGGKNNADVFDRAGLMFITNANAKASSAGG-TCSDTLRPKRS-VDLKKKFEDKAQKYG--AFREYCLSGTRSSPTLETCKDRANRVTLPNKKTRRDYEKEKYCRLAFEQCCVFAKDLRKENAEN-IILSRAAIDFLMDAPLSQVRSYFPESWLWEEHLSKSGSVSISKTLPDSITTWELKAVGVFNEGICVSD-KRIPVSQDIWVDVPLPYSMVRGEQILLKGSVYNQRSSGIKFTVTLTASSAVCVFHG--AQQGKPDKTNENSGQVAGGSVAMVSFYIMALEAGTHTLTFTLTTDWITESVVKKLRVVPEGIRMEEYIGKRIDPNGVFGTPMRKLEFKNVIPPKIVPKSSVDRIITVNGEVLGDILSILNNPEGIKMLTNLPRGSAELELMSLLPVYYVYHYLDKTEKWNILGKEAAASEKELKRKMQAGITSIMSFQLKNGEAFSMWAQKDKTPSTWVTALIIKTLSDIHEYVYVDTDVLANAIHWLIKNCQNEDGSFSELAKTNPHKLMGAG-VGVTEKSVYLTSYVMIGIKNALKIPNLKLQVFKDALDRGMQYLISRFRKSSHKIESLYVRAIASYAMTVADIDDGTAVNVYENIKKKAKIDGNPPRVCFWQESDTNIDPLKPSSVTAKSVETTVYVLLNTLTRGETEYAKPILNWLTQDQRYGGGVYSTQDTILTLEALTMYSIKAREANLNMVVDIEYKTRGERISRIQLTQQKPVAKPIEVTQNDDVIVKTAMSTGVSFVKLKTVYYVMTESNKSCLFDTTIDIHDSDQNSDDPMLLS--QRIVACAKFKPPENSLETESALTVMEINLPTGVTPVLEDLDEYQNGLESRISNYEVIGDKVVLQIDSIPSDNFYCVGFRILEEFETGMTKASEFTVYEYQAPAFKCTKLYQKQTRKLLRLCEEDHCQCMAAECCNFKSTIDPAITADQRTADICKESVKYALKVVIDSSEAGGDFVTYKATVQSVLKKGETDDLKTDSEVEFIKKASCNSTQFEIGKQYLTMTAESMKIQVNRAYKYKFPLDSEAWVDWWPLESDCSDANCKQYVKVLEGFEFEYLLNGCDLMSSR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. ::*:: :: **:.*:*:***::*:.:**.:*:*:.*: : . : :*. : :. ::*.. *::* :* * : .::.* : : ***:.:*. *:.. ::*:* **:***:****:***:*.*::*****.::*: : * ..*** **.* :*:::: * * . :* **** :* **:*.* *.* .:* **.** **:****** :**.** * .:*. :**..*::.:.*:*. . * .*:: ** . ::. :: .: : * :* :: :* .:*:. : . :*.:**: * : **:**:*:** :. :*:* :*:.*.::*** *:***:*:.::. ***.* : * .*.**: * : *:: :.:*. . ::. **** *. *:*:.*. :* ..*: .. . *. .* :* *:.: *:** . : . : **::::* *. . .: :.* *:****::::.* ::. . : *.:** :* :****:******:: **:.****:*:.*:::: ** ::*::.** * . :.:. : :* **::*** *:: :: . * .:::::* :: ******* *** :**:**. *** *:*****. * . .*.: **.:* *::*:*: * ** . :: * .*: . ***::*. *::: * ** :**..*..:* : ..: : *.* :. *: . .::*********** * .:. :****:****::.:*: : ****:* : * ::::::: :***:****** ***:*** :** :* *.::* ..:*. . . . :. :: *.* :*:* ::.** * *.:.*:* * : .: :**.*******:: *.* * :**.*: * *: ** ** .:***:.:.**::*:* ::*::** : . ***::**:**:**** ****: **:**:***: ::***: :. ..:.*::*:: *: *:**:: . ::*:* . :.***:**: ::.*.:: :** : : :.*:: **::: * ::***.* :: * ** *: . . *:::***:: :***::*..* :. ** :. .:*:.. : :* :. ** :**:::.* . : . ::::* :.*:** :*::. . *. *.: ** ****.*.** :*. : :*.:*:::**:::******.******* ::*.** **: :: .*.* ::: ** .* : . ::*::: :.:*:** ***::*.*. .:*:: * :.** : : *:: * * .** :* : . * :**:***.:**..:. : *: :**:*.****: . *** :*::. :::*:: ..:*:**::**** :* ** ***:* *:.*: ..: ******: * :** :*. . :: ::** * *: *:* ::: :* :*:*: *. ** . ** ** * * . **.*.**: *.**: :**: **** :*..::: *:*** * * ::*: * :::* :**** :*:::** :: *. .*: :: *: * : :**.* ", "identical_positions": 580, "similar_positions": 627, "identity": "33.6%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120510-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49766-1", "uniprot_id": "VEGFB_MOUSE", "id": "P49766-1", "name": "Vascular endothelial growth factor B", "aln": "----MSPLLRRLLLVALLQL----ARTQAPVSQFDGPSHQKKVVPWIDVYARATCQPREVVVPLSMELMGNVVKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQVRMQILMIQYPSSQLGEMSLEEHSQCECRPKK------KESAVKPDRVAIPHHRPQPR--------SVPGWDSTPGASSPADIIHPTPAPGSSARLAP-SAVNALTPGPAAAAADAAASSIAKGGA----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P49765-1", "uniprot_id": "VEGFB_HUMAN", "id": "P49765-1", "name": "Vascular endothelial growth factor B", "aln": "----MSPLLRRLLLAALLQL----APAQAPVSQPDAPGHQRKVVSWIDVYTRATCQPREVVVPLTVELMGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQVRMQILMIRYPSSQLGEMSLEEHSQCECRPKK------KDSAVKPDRAATPHHRPQPR--------SVPGWDSAPGAPSPADITHPTPAPGPSAHAAP-STTSALTPGPAAAAADAAASSVAKGGA----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B3Z6-1", "uniprot_id": "A0A8M2B3Z6_DANRE", "id": "A0A8M2B3Z6-1", "name": "", "aln": "MGIKLRVILGMFQFVTLTRIPTQCARTQSDHWMPTQSHKSGEVVRWLDVFQRSGCHPRETLVEVWQEFPWETNHLFLPSCVTLRRCGGCCSDEALECVPSQTHTLVMELMKTSYMKHELVQLPFIEHNQCECRLKANLYAEPTRQGPQTTRRGRKRHRGKPKRKKHMGKNSMMLVPTTPPPPPPPTLPPSSAPPTPAREACPPCPIRKMTSHPPSCECRCSLREVSCTKRGKTLNQSSCRCETQSE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* : :.:* :: * :*: . :. :** *:**: *: *:***.:* : *: . : ::*****::******.*:.*****: * : *::: * . :* ::.: **.***** * . .. :. * . :** :*: *: ::* ...*. : .:..* .: . .* .. :*. *.:. . .: .:: ", "identical_positions": 56, "similar_positions": 81, "identity": "22.76%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120511-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P43253-1", "uniprot_id": "PI2R_RAT", "id": "P43253-1", "name": "Prostacyclin receptor", "aln": "MVASGGRPDGPPSITPESPLIVGGREWQGMAGSCWNITYVQDSVGPATSTLMFVAGVVGNGLALGILGAR---RRSHPSAFAVLVTGLAVTDLLGTC-FLSPAVFVAYARNSSLLGLAHGGTMLCDTFAFAMTFFGLASTLILFAMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCCLFCSLPLLGLGEHQ-QYCPGSWCFIRMRSPQPG-----GCAFSLAYASLMALLVTSIFFCNGSVTLSLCHMYRQQRRHHGSFVPTSRAR---------EDEVYHLILLALMTGIMAVCSLPLTIRGFTQAIAPDSR-EMGDLHAFRFNAFNPILDPWVFILFRKAVFQRLK-FWLCCLCARSVHGDLQTPLSRPVSGRRDTLAPDSLQAKEGNWVPLSTWGTGQVAPLTAVPLSGGDGCSVGMPSKTEAVVACSLC", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P43252-1", "uniprot_id": "PI2R_MOUSE", "id": "P43252-1", "name": "Prostacyclin receptor", "aln": "MMASDGHP-GPPSVTPGSPLSAGGREWQGMAGSCWNITYVQDSVGPATSTLMFVAGVVGNGLALGILGAR---RRSHPSAFAVLVTGLAVTDLLGTC-FLSPAVFVAYARNSSLLGLAHGGTMLCDTFAFAMTFFGLASTLILFAMAVERCLALSHPYLYAQLDGPRCARFALPSIYAFCCLFCSLPLLGLGEHQ-QYCPGSWCFIRMRSAQPG-----GCAFSLAYASLMALLVTSIFFCNGSVTLSLYHMYRQQRRHHGSFVPTSRAR---------EDEVYHLILLALMTVIMAVCSLPLMIRGFTQAIAPDSR-EMGDLLAFRFNAFNPILDPWVFILFRKAVFQRLK-FWLCCLCARSVHGDLQAPLSRPASGRRDPPAPTSLQAKEGSWVPLSSWGTGQVAPLTAVPLTGGDGCSVGMPSKSEAIAACSLC", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P43119-1", "uniprot_id": "PI2R_HUMAN", "id": "P43119-1", "name": "Prostacyclin receptor", "aln": "-----------------------------MADSCRNLTYVRGSVGPATSTLMFVAGVVGNGLALGILSAR---RPARPSAFAVLVTGLAATDLLGTS-FLSPAVFVAYARNSSLLGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLALPAIYAFCVLFCALPLLGLGQHQ-QYCPGSWCFLRMRWAQPG-----GAAFSLAYAGLVALLVAAIFLCNGSVTLSLCRMYRQQKRHQGSLGPRPRTG---------EDEVDHLILLALMTVVMAVCSLPLTIRCFTQAVAPDSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVFQRLK-LWVCCLCLGPAHGDSQTPLSQLASGRRDPRAPSAPVGKEGSCVPLSAWGEGQVEPLPPTQQS--SGSAVGTSSKAEASVACSLC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FE45-1", "uniprot_id": "E7FE45_DANRE", "id": "E7FE45-1", "name": "Prostacyclin receptor", "aln": "---------------------------MLSNQSCENITSIEANGNPGTSTVMFIAGVVGNLIALAILGVHQKDRRTKSSVFCILVTGLALTDLLGTC-LLSPPVFICYAYRTSLVGLT-GDQRLCGLFAFAMTFFILASMLILCAMAVERCLAISHPYFYSKHVRRSFAKIVLLLIYLFTFVFCLMPFFGYGRHK-QYCPGTWCFIKMEVEEGDDEERRSLAFSLSYAVLMALLIAIVFMCNGSVIVSLCRMHRSQLTRRGSVVSAGRKRRLSTWFGQGEEEMDHLLLLASMTLIFVICSLPLTICGFENAISPVGN-DQRNLTAFRFSAFNPILDPWIFIIFRKAVFHHIRALFRCCFPREAVKTTAQSSQELKAEDIKHS---SSIQSKIYHSLPQ---------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VVJ1-1", "uniprot_id": "Q9VVJ1_DROME", "id": "Q9VVJ1-1", "name": "G-protein coupled receptors family 1 profile domain-containing protein", "aln": "--------------METTTPVLDLLMPHNSTTVAPPKALYANRNRLIIGVIIMVLGVFGNSLALFILARK---KLNKNSKYTLMLRCLATNNLVALLGMLTTTLLKMYLSKEVLQSFIRVDCVG----LVVWRFFGLSSGCIAAVMAAERWMALARPFIYHKHITYELIRKSINSILMIAVVITFLPFVGFGAYIDESNPDQLKCIRYRDAPGVWNKTYAVLFMVFGTLLCIVIVACNLFVAHTLLCVIGRSRTAKRHMHYDLVSRDKNSAISID--PESSSGTTLYQTQLSTGSGNSHRSVQPARQYRHSVSVTMAATDSSPVEIKFAKLMAFLS-ISFVICWMPQMIAIPLAIAPNRVPASNKFFIIADVLTALHFTSDPYVYVLSRSKSINWSLLGCIKRWRSGWRPGGLRRSQSDQSRMRTTMTEANTLEFN-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . : ..:::: **.** :** **. : : : * : ::: ** .:*:. :*:..:: * . * .: . .. ** *:* * .**.** :*:::*::* : : : * : :: :*:.* * : : *. :: . . * : : * :::: :: :: : : : : .. . : ... * * : :::: . ::* : .:*. *:: . : : . : : .. .* ", "identical_positions": 40, "similar_positions": 103, "identity": "9.15%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120511-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P78549-2", "uniprot_id": "NTH_HUMAN", "id": "P78549-2", "name": "Endonuclease III-like protein 1", "aln": "---MTALSARMLT---RSRSLGPGAGP--------------------RGCREEPGPLRRREAAAEARKSHSPVKRPRKAQRLR-VAYEGSDSEKGEGAEPLKVP-------------------VWEPQDWQQQLVNIRAMRNKKDAPVDHLGTEHCYDSSAPPKVRRYQVLLSLMLSSQTKDQVTAGAMQRLRARGLTVDSILQTDDATLGKLIYPVGFWRSKVKYIKQTSAILQQHYGGDIPASVAELVALPGVGPKMAHLAMAVAWGTVSGIAVDTHVHRIANRLRWTKKATKSPEETRAALEEWLPRELWHEINGLLVGFGQQTCLPVHPRCHACLNQALCPAAQGL--------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O35980-1", "uniprot_id": "NTH_MOUSE", "id": "O35980-1", "name": "Endonuclease III-like protein 1", "aln": "---MNSG-VRMVT---RSRSRATRIAS--------------------EGCREELAP---REAAAEGRKSHRPVRHPRRTQKTH-VAYEAANGEEGEDAEPLKVP-------------------VWEPQNWQQQLANIRIMRSKKDAPVDQLGAEHCYDASASPKVRRYQVLLSLMLSSQTKDQVTAGAMQRLRARGLTVESILQTDDDTLGRLIYPVGFWRNKVKYIKQTTAILQQRYEGDIPASVAELVALPGVGPKMAHLAMAVAWGTISGIAVDTHVHRIANRLRWTKKMTKTPEETRKNLEEWLPRVLWSEVNGLLVGFGQQICLPVHPRCQACLNKALCPAAQDL--------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F1QBP9-1", "uniprot_id": "F1QBP9_DANRE", "id": "F1QBP9-1", "name": "Endonuclease III-like protein 1", "aln": "MYMFSRLTVRMNSPYFTSAALDSSATETMGKSTINKDGIRRLRSRMAQGLRSEDDPPKVKAEVQEKSISDDPTHAHNPADCVKSTSYNTTSKMKEEPDQALLSPRKRGRGHLKVEYETEGVGLKREPYDWRTQLSFIREMRSKRDAPVDQMGAEKCYDTQGLPEVRRYQVLISLMLSSQTKDQVTAGAMQRLREHGLSVDGILKMDDETLGKLIYPVGFWRTKVKYIKQATALIQQEFGGDIPNTVEGLIRLPGVGPKMAHLAMDIAWNQVSGIGVDTHVHRISNRLGWTKKETKTPEETRRALEEWLPRDLWSEINWLLVGFGQQVCLPVGPLCSVCLNQHTCPSAHRSSPSKKIKSSPAKPNNKLASPTALVKEEPEDTSAQRVSHQRRKNTGPQLNQQDLSASRQETPSLARNRRKGRAGAPLSGQT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. .** : * : . .* *.* * : . * *. *.: . :: : .:*: :. : * :.* * ** :*: ** ** **.*:*****::*:*:***:.. *:*******:********************* :**:*:.**: ** ***:*********.*******::*::**.: **** :* *: ************* :**. :***.********:*** **** **:***** ******* ** *:* ******** **** * * .***: **:*: ", "identical_positions": 169, "similar_positions": 64, "identity": "39.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120514-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q7TMB0-1", "uniprot_id": "PLPR3_RAT", "id": "Q7TMB0-1", "name": "Phospholipid phosphatase-related protein type 3", "aln": "MIAKKE--KNKTPKDSMTLLPCFYFVELPIVASSVVSLYFLELTDLFQPAKVGFQCHDRSLSMPYVETNEELIPLLMLLSLAFAAPAASIMVGEGMVYCLQSRLWGR--GPGGVEGSINAGGCNFNSFLRRTVRFVGVHVFGLCATALVTDVIQLATGYHTPFFLTVCKPNYTLLGTSCEANPYITQDICSGHDTHAILSARKTFPSQHATLSAFAAVYVSMYFNSVISDATKLLKPILVFAFAIAAGVCGLTQITQYRSHPVDVYAGFLIGAGIAAYLACHAVGNFQAPPAEKVPTPAP-AKDALRVLTQRGHESMYQQ-NKSVSTDELGPPGRLEGVPRPVAREKTSLGSLKRASVDVDLLAPRSPMGKEGMVTFSNTLPRVSTPSLDDPSRRHMTIHVPLDASRSRQLISEWKQKSLEGRGLGLPDEASPAHLRAPAEQVAEEEEEEEEEEEEEEEEEEEEEGPVPPSLYPTVQARPGLGPRVILPPRPGPQPLIHIPEEVVQAGAGLSPKSS-ASVRAKWLSMVEKGGGPVAVAPPQPRVANPPRLLQVIAMSKAAGGP-----KAETASSSSASSDSSQYRSP--SDRD-SASIVTIDAHAPHHPVVHLSAG-STPWEWKAK----VVEGEGGYELGDLAR-GFRSSCKQPGIGPGSPVSDVDQEEPRFGAVATVNLATGEGLPPPGASEGALGAGSRESTLRRQVG--ALGERE---VEAEAESYYRRMQARRYQD", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7TPB0-1", "uniprot_id": "PLPR3_MOUSE", "id": "Q7TPB0-1", "name": "Phospholipid phosphatase-related protein type 3", "aln": "MLAMKE--KNKTPKDSMTLLPCFYFVELPIVASSIVSLYFLELTDLFKPAKVGFQCYDRALSMPYVETNEELIPLLMLLSLAFAAPAASIMVGEGMVYCLQSRLWGR--GPGGVEGSINAGGCNFNSFLRRTVRFVGVHVFGLCATALVTDVIQLATGYHTPFFLTVCKPNYTLLGTSCESNPYITQDICSGHDTHAILSARKTFPSQHATLSAFAAVYVSMYFNAVISDTTKLLKPILVFAFAIAAGVCGLTQITQYRSHPVDVYAGFLIGAGIAAYLACHAVGNFQAPPAEKVPTPAP-AKDALRALTQRGHESMYQQ-NKSVSTDELGPPGRLEGVPRPVAREKTSLGSLKRASVDVDLLAPRSPMGKEGMVTFSNTLPRVSTPSLDDPARRHMTIHVPLDASRSRQLIGEWKQKSLEGRGLGLPDEASPVHLRAPAEQVAEEEEEEEEEEEEEEEEEEEE-GPVPPSLYPTVQARPGLGPRVILPPRPGPQPLVHIPEEGVQAGAGLSPKSSSSSVRAKWLSVAEKGGGPVAVAPSQPRVANPPRLLQVIAMSKAAGGP-----KAETASSSSASSDSSQYRSP--SDRD-SASIVTIDAHAPHHPVVHLSAG-STPWEWKAK----VVEGEGSYELGDLAR-GFRSSCKQPGMGPGSPVSDVDQEEPRFGAVATVNLATGEGLPPPGASEGALGAGSRESTLRRQVG--GLAERE---VEAEAESYYRRMQARRYQD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6T4P5-1", "uniprot_id": "PLPR3_HUMAN", "id": "Q6T4P5-1", "name": "Phospholipid phosphatase-related protein type 3", "aln": "MISTKE--KNKIPKDSMTLLPCFYFVELPIVASSIVSLYFLELTDLFKPAKVGFQCYDRTLSMPYVETNEELIPLLMLLSLAFAAPAASIMVAEGMLYCLQSRLWGRAGGPAGAEGSINAGGCNFNSFLRRTVRFVGVHVFGLCATALVTDVIQLATGYHTPFFLTVCKPNYTLLGTSCEVNPYITQDICSGHDIHAILSARKTFPSQHATLSAFAAVYVSMYFNSVISDTTKLLKPILVFAFAIAAGVCGLTQITQYRSHPVDVYAGFLIGAGIAAYLACHAVGNFQAPPAEKPAAPAP-AKDALRALTQRGHDSVYQQ-NKSVSTDELGPPGRLEGAPRPVAREKTSLGSLKRASVDVDLLAPRSPMAKENMVTFSHTLPRASAPSLDDPARRHMTIHVPLDASRSKQLISEWKQKSLEGRGLGLPDDASPGHLRAPAEPMAEEEEEEEDEEEEEEEEEEEDEGPAPPSLYPTVQARPGLGPRVILPPRAGPPPLVHIPEEGAQTGAGLSPKSG-AGVRAKWLMMAEKSG---------AAVANPPRLLQVIAMSKAPGAPG--PKAAETASSSSASSDSSQYRSP--SDRD-SASIVTIDAHAPHHPVVHLSAG-GAPWEWKAAGGGAKAEADGGYELGDLAR-GFRGGAKPPGVSPGSSVSDVDQEEPRFGAVATVNLATGEGLPPLGAADGALGPGSRESTLRRHAGGLGLAERE---AEAEAEGYFRKMQARRFPD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TEN8-1", "uniprot_id": "A0A8N7TEN8_DANRE", "id": "A0A8N7TEN8-1", "name": "Phospholipid phosphatase-related protein type 3", "aln": "MITAREKIKKKPPKDSLTLLPCFYFVELPIVASSMVSLYFLELTDVLQPAQVGFRCHDRSLSMPYVDSGDELIPLLMLLSLAFAGPAASIMMGEGLLYCMQSKLKVR----PGIEGSINAGGCNFNSFLRRTVRFVGVHVFGLCATALVTDVIQLATGYHTPFFLTVCKPNYTIPGVSCDKNPYITKDICAGQDQHAILSARKTFPSQHATLSSFAAVYISMYFNSTISDSTKLLKPVLVFAFAIAAALTGLTQITQYRSHPIDVYVGFCIGAGIAAYLAFHAVANFKSPEDAVIPQPPPQQKDALRALAQRGHDSVYNKGHASESNEEITSPASLDGLNRPVQREKTSLGSLKRASVDVELLAPRSPMGKETMVTFSNTLPRATAP--EEPTRRLVTVPVPLDPMRSQQLVSEWKQKSMEMRGGSLPDEDTS----------DQGSDGGDDTTTEEDSIHSSVYSSVP---HMSKPANPPTGPKAVMTPRPPTQSSIPPP---------VSPKSA--STRAKWLSITEKSGANIP----VVKAGNQPRIMQVIAMSKQQGLLSGSAKSSETSSSSGTSSITGTESSPNRSERDGSPGIITVDAHAPHHPVVRMTSNPNNPWEWRGS---SDGNMAESYELKNVNREGSRIYRHVRSGSPCSSASEADHGPPQPPQPPQPPLPP--QLPP-------VGNTSEARSLRRKTP-LVLLDREGNQNHTEQDNYYKKLQSGRHF-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: :* *:* ****:*****************:**********:::**:***:*:**:******::.:**************.******:.**::**:**:* * * ***********************************************************: *.**: *****:***:*:* ******************:*****:*****:.***:******:*********.: ************:***.** ********** ***.**::* . *.* *****.*:****:*:*:: : * *.:*: .*. *:* *** ****************:********.** *****:****.::* ::*:** :*: ****. **:**:.******:* ** .***: :. : .: :: **:. ... ...* : : *.* **:.::.**. . . : * :****. ..***** :.**.* ..* **::******* * :**:***.:** :. ** *:** *..*:*:**********::::. . ****:. : .*** :: * * * : . .* *..*:.*: *: . *.. *** :* *. :***:. * :** .:* :.*::::*: *. ", "identical_positions": 401, "similar_positions": 165, "identity": "54.04%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120514-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R9F7-1", "uniprot_id": "M0R9F7_RAT", "id": "M0R9F7-1", "name": "", "aln": "--MGSKETLKEEAFLGSTEDGADFDQDMLPVMET-FEINDPVPKKRNGRTLCMAVMAIHLILLTAGTALLLIQVLNLQEQFQSLEMCCDNGTLAAEDKPFFS--LQWARPKTHIVSGAQGLQALQAQLSWVHTSQEQLRQQVDNLTQNPELFRIKGERGSP---GPKGAPGAPGIPGLPGPSAAKGEKGAAGRDGTPGVRGPQGPPGTKGEAGLQGFTGAPGKQGADGAPGPQGEKGSKGDKGLTGPKGEHGTKGDKGDLGLPGSKGDTGMKGDRGVTGSPGAQGNKGDAGKPGLPGLAGSPGAKGDQGKLGVQGPPGPPGAPGQSGAKGEPGRTGPPGPTGPPGIAGNPGAAGLKGSKGDIGIQ------GQKGTKGES--GVPGLVGRKGDTGSPGLAGPKGEPGRAGLKGEPGMKGSSGQQGQKGEKGQKGDF-----NLVVRIVGGTSRGRAEVYYNNVWGTICDDGWDNNDATVFCRMLGYSSGRGLGSFGGGTGKIWLDDVSCLGTEATLWDCRKSSWGSHNCNHNEDAGVECR-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q60754-1", "uniprot_id": "MARCO_MOUSE", "id": "Q60754-1", "name": "Macrophage receptor MARCO", "aln": "--MGSKELLKEEDFLGSTEDRADFDQAMFPVMET-FEINDPVPKKRNGGTFCMAVMAIHLILLTAGTALLLIQVLNLQEQLQMLEMCCGNGSLAIEDKPFFS--LQWA-PKTHLVPRAQGLQALQAQLSWVHTSQEQLRQQFNNLTQNPELFQIKGERGSP---GPKGAPGAPGIPGLPGPAAEKGEKGAAGRDGTPGVQGPQGPPGSKGEAGLQGLTGAPGKQGATGAPGPRGEKGSKGDIGLTGPKGEHGTKGDKGDLGLPGNKGDMGMKGDTGPMGSPGAQGGKGDAGKPGLPGLAGSPGVKGDQGKPGVQGVPGPQGAPGLSGAKGEPGRTGLPGPAGPPGIAGNPGIAGVKGSKGDTGIQ------GQKGTKGES--GVPGLVGRKGDTGSPGLAGPKGEPGRVGQKGDPGMKGSSGQQGQKGEKGQKGES-----FQRVRIMGGTNRGRAEVYYNNEWGTICDDDWDNNDATVFCRMLGYSRGRALSSYGGGSGNIWLDNVNCRGTENSLWDCSKNSWGNHNCVHNEDAGVECS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UEW3-1", "uniprot_id": "MARCO_HUMAN", "id": "Q9UEW3-1", "name": "Macrophage receptor MARCO", "aln": "--MRNKKILKEDELLSETQQ-AAFHQ---IAMEP-FEINVPKPKRRNGVNFSLAVVVIYLILLTAGAGLLVVQVLNLQARLRVLEMYFLNDTLAAEDSPSFSL-LQSAHPGEHLAQGASRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQ------GQQGRKGES--GVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERGEN-----SVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALYKVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BH24-1", "uniprot_id": "A0A8M2BH24_DANRE", "id": "A0A8M2BH24-1", "name": "", "aln": "METEVDDFPGKASIFSQVNPLYSNNMKLCEAERYDFQHSEPKTMKSASKRHCVPVLILLFLLLIGLNSFLAYKVFTLEAWVHTHCTSAQNHELTSASSFQLGSSKNEVECFTDLCGTDGTLEHLRTQINQLNATAEKAIVCPPGPPGPPGSNGIPGFPGQK---GIPGSPGRVGEPGAPGQKGQTGDPGIKGERGMVGFPGIPGAPGRKGDSGERGLQGLPGNDGSPGQDGRTGPQGMPGPSGSQGVKGDPGLKGERGDQGPPGPTGPQGSSGARGLQGIPGEKGSPGPKGDTG-VGLQGPTGQQGQKGSQGVPGVPGARGANGEKGDRGLSGVKGDPGLKGERGDQGQPGPTGPQGSSGARGLQGIPGGKGSPGPKGDTGVGLRGLTGQQGQKGSQGLPGVPGARGANGEKGDRGLSGQKGDQGPKGEKGDAGAKGASGGSQVVRLVGSSTRGRVEVFYQNVWGTVCDDSFDNLDALVVCRMLGFQRSTQVYTDGSGSGRIWLDELRCTGTESSIFNCPHAGMGINNCGHGEDVGVSCA-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. : ::...: . . . *: . * . : . .:.*: : ::** . .:* :*:.*: .: * *: .. :. : . .: *: *::*:. :..: *: . . * * * * * *: * * ** ** . .* * *. * * * *.** **::* :* * **::*: * * * :* * * * **: * **::** * ** .* * .* * * ** :*. * * .* ** * .* :*::*. *: * **. ** * * :* .* * ** * * *.** :* :**.* *:* *. * **:: *: * .* :*: ** **.* * * * **: *:.*..*:** *****: * **::*.:.***.**:*.. ***:*** ::* ** *.*****:. . : . *.*:*.****:: * *** :::.* : . * ::* * **.**.* ", "identical_positions": 174, "similar_positions": 136, "identity": "32.16%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120516-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P81128-1", "uniprot_id": "RHG35_RAT", "id": "P81128-1", "name": "Rho GTPase-activating protein 35", "aln": "MMMARKQDVRIPTYNISVVGLSGTEKEKGQCGIGKSCLCNRFVRPSADEFHLDHTSVLSTSDFGGRVVNNDHFLYWGEVSRSLEDCVECKMHIVEQTEFIDDQTFQPHRSTALQPYIKRAAATKLASAEKLMYFCTDQLGLEQDFEQKQMPDGKLLVDGFLLGIDVSRGMNRNFDDQLKFVSNLYNQLAKTKKPIVIVLTKCDEGVERYIRDAHTFALSK---KNLQVVETSARSNVNVDLAFSTLVQLIDKSRGKTKIIPYFEALKQQSQQIATAKDKYEWLVSRIVKSHNENWLSVSRKMQASPEYQDYVYLEGTQKAKKLFLQHIHRLKHEHIERRRKLYLAALPLAFEALIPNLDEVDHLS---CIKAKKLLETKPEFLKWFVVLEETPWDETSHIDNMENER-IPFDLMDTVPAEQLYETHLEKLRNERKRAEMRRAFKENLETSPFITPGKPWEEARSFIMNEDFYQWLEESVYMDIYGKHQKQIIDRAKEEFQELLLEYSELFYELELDAKPSKEKMGVIQDVLGEEQRFKALQKLQAERDALILKHIHFVYHPTKETCPSCPACVDAKIEHLISSRFIR--PSDRNQKNSLSDPNIDR-INLVILGKDGLARELANEIRALCTNDDKYVIDGKMYELSLRPIEGNVRLPVNSFQTPTFQPHGCLCLYNSKESLSYVVESIEKSRESTLGRRDNHLVHLPLTLILVNKR-----GDTSGETLHSLIQQGQQIASKLQCVFLDPASAGIGYGRNINEKQISQVLKGLLDSKR--------NLNLVSSTASIKD---LADVDLRIVMCLMCGDPFSADDILSPVLQSQTCK-SSHCGSSNSVLLELPIGVHKKRIELSVLSYHSSFSIRKSRLVHGYIVFYSAKRKASLAMLRAFLCEVQDIIPIQLVALTDG--AIDVLDNDLSREQLTEGEEIAQEIDGRFTSIPCSQP-----QHKLELFHPFFKDVVEKKNIIEATHMYDNVAEAC-------STTEEVFNSPRAGSPLCNSNLQDS------------------------------EEDVEPP-SYHLFREDATLPSLSKDHSKFSMELEGNDGLSFIMSNFESKLNNKVPP-----------------------------------PVKPKPPVHFEITK---DLSYLDQGHREGQRKSMSSSPWMPQDGFDPSDYAEPMDAVVKPR-NEEENIYSVPHDSTQGKIITIRNINKAQSNGSGNGSDSEMDTSSLERGRKVSAV-SKPVLYR-----TRCTRLGRFASYRTSFSVGSDDE----LGPIRKKEEDQASQGYKGD---------------------------NAVIPYETDEDPRRRNILRSL-RRNTKKPKPKPRPSITKATWESNYFGVPLTTVVTP--------EKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYSMQIDLVEAHKIN-------------DREQKLHALKEVLKKFPKENHEVFKYVISHLNRVSHNNKVNLMTSENLSICFWPTLMRPDFSSMDALTATR-SYQTIIELFIQQCPFFFYNRPISEPPGAAPGSPSAMAPTVP--------FLTSTPATS-----QPSPPQSPPPTPQSPMQPLLS-----SQLQAEHTL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91YM2-1", "uniprot_id": "RHG35_MOUSE", "id": "Q91YM2-1", "name": "Rho GTPase-activating protein 35", "aln": "MMMARKQDVRIPTYNISVVGLSGTEKEKGQCGIGKSCLCNRFVRPSADEFHLDHTSVLSTSDFGGRVVNNDHFLYWGEVSRSLEDCVECKMHIVEQTEFIDDQTFQPHRSTALQPYIKRAAATKLASAEKLMYFCTDQLGLEQDFEQKQMPDGKLLVDGFLLGIDVSRGMNRNFDDQLKFVSNLYNQLAKTKKPIVVVLTKCDEGVERYIRDAHTFALSK---KNLQVVETSARSNVNVDLAFSTLVQLIDKSRGKTKIIPYFEALKQQSQQIATAKDKYEWLVSRIVKNHNENWPSVSRKMQASPEYQDYVYLEGTQKAKKLFLQHIHRLKHEHIERRRKLYLAALPLAFEALIPNLDEVDHLS---CIKAKKLLETKPEFLKWFVVLEETPWDATSHIDNMENER-IPFDLMDTVPAEQLYETHLEKLRNERKRAEMRRAFKENLETSPFITPGKPWEEARSFIMNEDFYQWLEESVYMDIYGKHQKQIIDRAKEEFQELLLEYSELFYELELDAKPSKEKMGVIQDVLGEEQRFKALQKLQAERDALILKHIHFVYHPTKETCPSCPACVDAKIEHLISSRFIR--PSDRNQKNSLSDLNIDR-INLVILGKDGLARELANEIRALCTNDDKYVIDGKMYELSLRPIEGNVRLPVNSFQTPTFQPHGCLCLYNSKESLSYVVESIEKSRESTLGRRDNHLVHLPLTLILVNKR-----GDTSGETLHSLIQQGQQIASKLQCVFLDPASAGIGYGRNINEKQISQVLKGLLDSKR--------NLNLVSSTASIKD---LADVDLRIVMCLMCGDPFSADDVLSPVLQSQTCK-SSHCGSSNSVLLELPIGLHKKRIELSVLSYHSSFSIRKSRLVHGYIVFYSAKRKASLAMLRAFLCEVQDIIPIQLVALTDG--AIDVLDNDLSREQLTEGEEIAQEIDGRFTSIPCSQP-----QHKLELFHPFFKDVVEKKNIIEATHMYDNVAEAC-------STTEEVFNSPRAGSPLCNSNLQDS------------------------------EEDVEPP-SYHLFREDATLPSLSKDHSKFSMELEGNDGLSFIMSNFESKLNNKVPP-----------------------------------PVKPKPPVHFDITK---DLSYLDQGHREGQRKSMSSSPWMPQDGFDPSDYAEPMDAVVKPR-NEEENIYSVPHDSTQGKIITIRNINKAQSNGSGNGSDSEMDTSSLERGRKVSAV-SKPVLYR-----TRCTRLGRFASYRTSFSVGSDDE----LGPIRKKEEDQASQGYKGD---------------------------NAVIPYETDEDPRRRNILRSL-RRNTKKPKPKPRPSITKATWESNYFGVPLTTVVTP--------EKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYSMQIDLVEAHKIN-------------DREQKLHALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFSSMDALTATR-SYQTIIELFIQQCPFFFYNRPISEPPGAAPGSPSAMAPTVP--------FLTSTPATS-----QPSPPQSPPPTPQSPMQPLLS-----SQLQAEHTL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NRY4-1", "uniprot_id": "RHG35_HUMAN", "id": "Q9NRY4-1", "name": "Rho GTPase-activating protein 35", "aln": "MMMARKQDVRIPTYNISVVGLSGTEKEKGQCGIGKSCLCNRFVRPSADEFHLDHTSVLSTSDFGGRVVNNDHFLYWGEVSRSLEDCVECKMHIVEQTEFIDDQTFQPHRSTALQPYIKRAAATKLASAEKLMYFCTDQLGLEQDFEQKQMPDGKLLVDGFLLGIDVSRGMNRNFDDQLKFVSNLYNQLAKTKKPIVVVLTKCDEGVERYIRDAHTFALSK---KNLQVVETSARSNVNVDLAFSTLVQLIDKSRGKTKIIPYFEALKQQSQQIATAKDKYEWLVSRIVKNHNENWLSVSRKMQASPEYQDYVYLEGTQKAKKLFLQHIHRLKHEHIERRRKLYLAALPLAFEALIPNLDEIDHLS---CIKAKKLLETKPEFLKWFVVLEETPWDATSHIDNMENER-IPFDLMDTVPAEQLYEAHLEKLRNERKRVEMRRAFKENLETSPFITPGKPWEEARSFIMNEDFYQWLEESVYMDIYGKHQKQIIDKAKEEFQELLLEYSELFYELELDAKPSKEKMGVIQDVLGEEQRFKALQKLQAERDALILKHIHFVYHPTKETCPSCPACVDAKIEHLISSRFIR--PSDRNQKNSLSDPNIDR-INLVILGKDGLARELANEIRALCTNDDKYVIDGKMYELSLRPIEGNVRLPVNSFQTPTFQPHGCLCLYNSKESLSYVVESIEKSRESTLGRRDNHLVHLPLTLILVNKR-----GDTSGETLHSLIQQGQQIASKLQCVFLDPASAGIGYGRNINEKQISQVLKGLLDSKR--------NLNLVSSTASIKD---LADVDLRIVMCLMCGDPFSADDILFPVLQSQTCK-SSHCGSNNSVLLELPIGLHKKRIELSVLSYHSSFSIRKSRLVHGYIVFYSAKRKASLAMLRAFLCEVQDIIPIQLVALTDG--AVDVLDNDLSREQLTEGEEIAQEIDGRFTSIPCSQP-----QHKLEIFHPFFKDVVEKKNIIEATHMYDNAAEAC-------STTEEVFNSPRAGSPLCNSNLQDS------------------------------EEDIEP--SYSLFREDTSLPSLSKDHSKLSMELEGNDGLSFIMSNFESKLNNKVPP-----------------------------------PVKPKPPVHFEITKG--DLSYLDQGHRDGQRKSVSSSPWLPQDGFDPSDYAEPMDAVVKPR-NEEENIYSVPHDSTQGKIITIRNINKAQSNGSGNGSDSEMDTSSLERGRKVSIV-SKPVLYR-----TRCTRLGRFASYRTSFSVGSDDE----LGPIRKKEEDQASQGYKGD---------------------------NAVIPYETDEDPRRRNILRSL-RRNTKKPKPKPRPSITKATWESNYFGVPLTTVVTP--------EKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDHNLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVEAHKIN-------------DREQKLHALKEVLKKFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFSTMDALTATR-TYQTIIELFIQQCPFFFYNRPITEPPGARPSSPSAVASTVP--------FLTSTPVTS-----QPSPPQSPPPTPQSPMQPLLP-----SQLQAEHTL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F8G5-1", "uniprot_id": "E7F8G5_DANRE", "id": "E7F8G5-1", "name": "Rho GTPase-activating protein 35", "aln": "MMMAKKQDARAPTYNLVVVGLSGTEKEKGQCGVGKSCLCNRFVRPSADDFHLDHTSVLSTSDFGGRVVNNDHFLFWGEAVRMLEEGAECRMHVVEQTEFIDDQTFQPHRSTALQPYIKRAASTKLASAEKLMYFCTDQLGLEQDFEQKQMPEGKLLVDGFLLCVDVSRGMNRNFDDQMKFVTNLYNQLAKTKKPVVLVLTKCDEGVERYIKDSHTFALAK---KNLQVVESSARSNVNVDLAFITLVQLIDKSRGKPKIIPYFEALKQQSQQIATAKDRYEWLVSRIVKNHNETWPNTNRRMQTSPEYKDYVFLEGTSKAKKLFQQHVHRLKQEHIERRRKIYLSTLPQALNSLVPDLDEIDHLS---WSGVQKVLETKREFSHWFVVLDDTPWETTPHIDNMEDER-IPQDLLETPVAEGIYESHLEQLHNERKRAEMRWEFKEKLTCSPFVTPGKRWEEARSFIMNEEFYQWLEEQEYIDIYNKYQKIITDQAKEDFQELLLEYSELFYELEVDAKPSKEKMGAIQEVLGDEQRFKALQKLQAERDALVLKHIHFVYHPTKETCPSSPHCVDGKIEQHLALRYPTRYSFDGSSKSQFGEGKVDR-INLVILGKDGLARELANEIRALCTNDERYVLDGRTYELTLRPIEGNVRLPVNSFHTPTFAPHGCLCLYNSKESLSYVVDSIEKLRESTIGRRETNLVQLPLSLLLVTKRGVGSISDIGGETAQTLIQQGQQVAGRFQCSYLEPASPGVGYGRNINDKHLNQILRGLLEMRRPSVSLGSSSPPLLPSLAGFRDSQQSTEGDLRIVMCLMCGDTYDVDQLLSPFLLPQHCRPLSNLSSGTSVLLDLSIGGQRLSIDLAILSYHSSFSLRKSRLVHGYIAVYSAKRKASMETLCAFLCEVQDIIPVQLLAVAET--QSELADSEAVRDQLAQGEELAHEIDARFSSVICGPGGVVGGLHRIDHFQPFFKEVVEKKTIVEATHMYDNVAEN---------VTNENVSSPRCSSP--SITLLDS------------------------------EDDIEPSPPYPTSRNDD---TLTRGGFKLPDLEGDSYSLISEITNLENKINNKVPP-----------------------------------QVRPKPNVTFDIPKTQNSSLYTDLALHGSNRRSLPSVTWP-EAGYDPSDYAEPMDAVAKPRPTEEENIYSVPHDSTQGKIITIRNANKSHSNGAGNGSDSEADSSSLERRRKLSALGVKPRLYR-----DRSKRLGKFSSFRTSF-IGSDDE----LGGTPKAKEDELG-AQKGD---------------------------TSLN--EEGEDPKKRNILRSLGRRTTKKTRPKARQTSLSKPPESNYFGVPLANVVTP--------ERPIPLFIEKCIHYIETTGLSTEGIYRVSGNKAEMESMQRQFDQDPNIDLVEKDMSVNTVAGALKSFFSELPDPLVPYSMQVELVEAFKIN-------------DREHRLHTMKDVLRRFPRENYDVFKYVITHLNKVSLNSRLNLMTSENLSICFWPTLMRPDFTTMDALTATR-TYQTIIETFIHQCAFFFYNQPFADTPSGLPGQPASPTATLSSGSAYSTSYASIQPVAPPFSPAQQSPPHSPPPTPQSPIQSLLPPLHPHHTPTEQHML", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VX32-1", "uniprot_id": "RG190_DROME", "id": "Q9VX32-1", "name": "Rho GTPase-activating protein 190", "aln": "----------MRQFNISVIGLSGTEKDRGQVGVGKSCLCNRFMRPMADDYFIDHISVLSQSDFSGRIVNNDHFLYWGDVRKTTEEGVEYQFNIIEQTEFMDDSTFQAFKVGKMDPYSKRCTATKVFSAEKLMYICKNQLGIEKEYEQKVMPDGRLSIDGFVVVFDVSPVPNRSVEKQVEFVQNVIATILKNKKPLVLVTTKNDDAYELYVREAEKISQRKDYKSTVQLIETSAHESINIDLAFLLLAQMIDKVKNRVKIISYQESAKSRKELLDTRSEAVTRLIRNQITDYHVLWSQGSKMLSQYREWNEFLNIFGHEAGQKLFRRHMKKLRDDHLNKKLHQYLDKFALALEYLLPDIGALNISDDDAWECARNYLQNHIEFEQYFFECPQASWTELVDMDEAEDEARIPFDVLETSEAETVFRNYLNSVQQDKKKIGWKQQFKMLLEESGFVTPGKQLSEVRVLFMGRECFEALSEHDCQQIYDIHQDDIIEKSKQNFVELLLEHAQYFLQFKNVDNITQEDVRQITDVIQEDSRYKMLDRLDQERRLMLVQHLRFIHCPIRDHCPFFYNCVDSLIEEVLSDKSASNHKTPSGGGWKSSGSGSDRTLNLLIVGSEHLASDLLNDIRICTGSKGEYIYENQTYYLNYRIANG----DMEAFKAIDVYSSGLICVYSNQQSFETLKDNLERTLLCNLELED-KFENLPIVLVYQPQD-------LKENEVEYLRNEGMRLSEMLHCDFIDHTQN--------HQKYVYDILNIVILSLK---------LTEMKSYEPYPS----NHTDLRILCCIFCGDQYDIENIVQPLVEESTLV----KANEHSIIVDVFIGDAKRRVEFILSSYHGTSQYR-DELIHGYIYFYSTKRRSSLANLS-ILAAQNANIPLQIIAVTESGGVNAFFNSDICQFLITEGNAVADRFKGSFMTFSADQY------VKFAFYNPFLKTAWDNKYEVENLHVEESITLDSGEGTLENSVNQMPRPPPRHESYMLSNTLGTDGSGSENYEMAPTRSLNSLNEERDISLDEIYDDNEKPKHLHQKWLEDKSDGRRNMNKNLIWNNFSGSTHAYTTGRRHIDSNLNKIRPKGPSQTLKVGEAPSRNCPAMSSSTFTLPTQQPGKLNMKNFQLVSDAVAKMNFTGSGSGSGSGSGSGSTGLGLGLGSGSGCMGDSFLEPVDKDGKRYDHAQLDGEDEDSEELAEYEQIYENEDCTESDSCASSTERRVRQQNAYYKASKKPVAAKKQKKKKVAIPVQTPRVPPFGSYVSPPEIPLHYQRMAVGGSGPEKPEPCVPEFMKSDKSPEYSMVPELAGAGIFGAENLPEYNMNQAKCLKDFEKLEKRRIKEETARQRKLQEKEKEQEKKLKRKLKQNAKGLVESAEAQFGKLMITSEQGEIPIFLNKCVEFIEKEGLDSEGIYRVPGSRAHVDMLFQRFEEDTNTEIDALDIPVNAVATALKDFFSKRLPPLFSKDIIKELEEIAGSRGVGNSKLNVEVKTDRSCRLIALKSLLQKLPPINFAILKYIFQHFVHVSDNSKLNSMDSKNLAICWWPTLIPIDFTDMGHFEQLRPYLEDIVQTMIDQFPYLFCGKDAFVMV------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*: *:*******::** *:*********:** **::.:** **** ***.**:*******:**:. : *: .* :::::*****:**.***..: ::** **.::**: *******:*.:***:*:::*** **:*:* :***:: .*** **..:.*::** *: : *.***:*:* ** *:. * *::::..:: * ..:*::*:**:..:*:**** *.*:*** :.: ***.* *: *.:.: : * .: *: . :..:: * . .: :. *::::: : * . .:*** :*:::*:.:*:::: : ** :. *:: *:*::. :: . .:: *:.: ** ::*. ::.* .:*: *:* ** *:::* ** ::. :*:.:::::*: : ** * * *:**** .*.* ::*..: :: *.* :**. :*. * :::*::* *****::: * ::: : ::*.: * :*: ::.*:* *::*: ** ::::*::*:: * :: ** ***. **. :: : . . . ** :**:*:*.: ** :* *:** .. .*: :.: * *. * :* :::*:: . . * :*:*..::*:. : :.:*: ..: .: :: :**: *: : : . * ::* ::: ::* ::: :. ::* : ::*. :: : : * . . ****: *::*** :. :::: *.: . .. *::::: ** : ::: : ***.: . * ..*:**** .**:**::*: * :*. : **:*::*::: . :.: : :::*: :*..:.. * :. .. :: ::**:* . ::* :* *: :. : ..: .** * . .* . ::: :* : :* . . : .. . .. **: * :: * :.* . . .. : . * ..: **:* * : : . :. .* : :.*:.....:: . .. . . : * : : *: *.*: :. : . : * : * *.* . : *. .:*.* .. *: . : : * : . . :.* *: : . : **:*:::*:.:** **.:******.*.::.:: : ::*::* * :: *:.**:** *:*.***: **.. .: :* * . **. :* ::*.:*:::* *. ::**:: *: :** *.::* * *:**:**:****: **: *. : * : *:: :*.* .::* .: ", "identical_positions": 373, "similar_positions": 540, "identity": "22.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120521-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4ADL7-1", "uniprot_id": "D4ADL7_RAT", "id": "D4ADL7-1", "name": "Xyloside xylosyltransferase 1", "aln": "MAPPFRCPRSRLAPGSAVPPPLWPPPAAGLRALECCFEWARLLGRRLRRMDLLRGGAACARAMARLGAVRSHYCALLLAAALAVCAFY-------------YLGSGRETFSSATKRLKEARAGA---AAPTPPVPELARGSAAPASGAKAKNLEGGLAVPVDYHLLMMFTKAEHNAALQAKARVALRSLLRLAKFEPHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEILRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPP--------------EGLPGFNSGVMLLNLEAMRQSPLYGHLLEPAWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFPAYFHCEGHVKIYHGNCNTPIPED", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U4G3-1", "uniprot_id": "XXLT1_MOUSE", "id": "Q3U4G3-1", "name": "Xyloside xylosyltransferase 1", "aln": "-------------------------------------------------MGLLRGGAACARAMARLGALRSHYCALLLAAALAVCAFY-------------YLGSGRETFSSATKRLKEARAGA---AAPTPPAPELARGSAAPASGAKAKSLEGGVVVPVDYHLLMMFTKAEHNAPLQAKARVALSSLLRLAKFEAHEVLNLHFVSEEASREVAKALLRELLPPAAGFKCKVIFHDVAVLTDKLFPVVEAMQKYFSAGSGTYYSDSIFFLSVAMHQIMPKEIPRIIQLDLDLKYKTNIRELFEEFDNFLPGAVIGIAREMQPVYRHTFWQFRHENPKTRVGDPPP--------------EGLPGFNSGVMLLNLEAMRQSPLYSHLLEPSWVQQLADKYHFRGHLGDQDFFTMIGMEHPELFHVLDCTWNRQLCTWWRDHGYSDVFQAYFRCEGHVKIYHGNCNTPIPED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NBI6-1", "uniprot_id": "XXLT1_HUMAN", "id": "Q8NBI6-1", "name": "Xyloside xylosyltransferase 1", "aln": "-------------------------------------------------MGLLRGGLPCARAMARLGAVRSHYCALLLAAALAVCAFY-------------YLGSGRETFSSATKRLKEARAGAP--AAPSPPALELARGSVAPAPGAKAKSLEGGGAGPVDYHLLMMFTKAEHNAALQAKARVALRSLLRLAKFEAHEVLNLHFVSEEASREVAKGLLRELLPPAAGFKCKVIFHDVAVLTDKLFPIVEAMQKHFSAGLGTYYSDSIFFLSVAMHQIMPKEILQIIQLDLDLKFKTNIRELFEEFDSFLPGAIIGIAREMQPVYRHTFWQFRHENPQTRVGGPPP--------------EGLPGFNSGVMLLNLEAMRQSPLYSRLLEPAQVQQLADKYHFRGHLGDQDFFTMIGMEHPKLFHVLDCTWNRQLCTWWRDHGYSDVFEAYFRCEGHVKIYHGNCNTPIPED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9V4-1", "uniprot_id": "E7F9V4_DANRE", "id": "E7F9V4-1", "name": "", "aln": "-------------------------------------------------MGVLR---VLWGIMGRISMFRSYQIVLLLAAALAVVAFY-------------YFGSEKQNFSSTTKRIKETQASHNSNRDDADLSIDIQPGHLESRPGAGAE-LEGK---PKRFHALMMFTKVDKSLSLQQKFQTAMRSMVKHGRFLEDEILVLHYVSDLGSQEFGEKMLPELLLDAS-FQYEVVFHNVDTLTEKLFPIVEAMQKHFSAGSGAYYSDAIFFLSVAMHRIMPAELKRIVQLDLDLKFRSNIRDLFQEFNHFPSDAVIGIAREMQPVYRHTFWQYRKENPKSRVGDPPP--------------DGLPGFNSGVMLLNLDSMRRSTVYNQLLEPERVARLADKYHFRGHLGDQDFFTMIGMEHTELFYPLTCGWNRQLCTWWRDHGYGDVFQLYYHCDGPVHIHHGNCNTPIPDD", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1D1-1", "uniprot_id": "Q9W1D1_DROME", "id": "Q9W1D1-1", "name": "Xyloside xylosyltransferase 1", "aln": "---MAKNSFKTLISQKHKTFPADLNMYGMKCKSQLLEDQENVTLIINRRNSIRQKPKSWAWTLLRCRWQKKLVLLLIFICVCVLIVFANTHLLVRGNILSAFLSSRLNKHSHAEK--QEARYPDIPATTPSVPPVLRPTHYLLNYSSTQLELSSHLNGLSSDYNIFVIYTRENY--HLNLKFDLFAHSLLKHT----SAQLHLHVITDSESQPSVLEILQRQIRRFR-RTVIYTIYDVKVCSSIIQDIAAKLSPYFSSTPNSYYSDSLFFLSLGLHRIADRSLNRAILLDCDIVFRSDVRLLFNEFDNFLPHQLYGLAPELTPVYRHILYRYRVRYPKTSFGNPYYPINNEGGNQHSRVHHGYPGLNSGVVLLLLNRIRNSKSYLEKLTHSEVHTLVAKYSFKGHLGDQDFFTLLGYEYPNLIYRLDCIWNRQLCTWWKDHGYSQIFDAYFRCEGNIKMYHGNCNTRIPE-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: : : * :. *:: .. .: .* ::.* :..* : * :*:: : ..: : . . :: ::::*: : *: * *::: * ** ::: *: :* . : :::* . :. : :. :. :**: .:****::****:.:*:* .: : : ** *: :::::* **:**: * . : *:* *: ***** ::::* . *:: .*.* .* **:****:** *: :*.* * . * * *. ** *:**********::* *:.:*:: * * *********:****.::* *::*:* ::::****** **: ", "identical_positions": 109, "similar_positions": 123, "identity": "23.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120524-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6G942-1", "uniprot_id": "A0A8I6G942_RAT", "id": "A0A8I6G942-1", "name": "", "aln": "MPVLCCVTRFSQQLEAGSVLPFSPGETPQGSRPEALHRASKENNLCVETTILLSTLLLETTTSFPYRTGSMESSDVELDFQRSVQAVLRELN-TPNPALQSNQGMWRWSLHKKMERNPGKSSVLVRILLRELEKAESEDARRVIIPLLLTLMSVLTKATGITEDLYHRAYTFCTRLLTLPAPYSTVALDCAIRLKTETAVPGTLYQRTVIAEQNLISELYPYQERVFLFVDPELVSASVCSALLLEIQAAQEQQTPEACMRHVVSHALQAALGEACHTGALNRKLQASSRRVLEYYFHAVVAAIEQVASEDSPSRLGHLERMEEIYCSLLGTATTRRRCVGDLLQDRLPSIPLPSPYITFHLWTDQEQLWKELVLFLRPRSQLRLSADLDALDLQGFRPDRDLARVS---TDSGIERDLPLGNDELPDPSSSEMERAALQRKGGIKKRVWPPDFFMPGSWDGPPGLHRR----TGRPSGDGELLPGVSRVHTARVLVLGDDRMVGRLAQAYYRLRKRETKKFCLTPRLSLQFYYIPVLAPQGTGQDPEASRKPELGELASFLGRVDPWYESTVNTLCPAILKLAEMPPCLDTSRTVDPFILDVITYYVRMGTQPIYFQLYKVKIFTN-LSHDPIEDIFLMELKVKTQDSKSP--------KEGSSPRRRGAAEGTGAELSMCYQKALLSHRPRKVTVSLRATGLVLKAIPAGDTEVSGFSHCTSPNAASAADCSCLHVSVTEVVKTSNLAGRSFTTSTNTFRTSSIQVQSQDQRLLTLWLDKDGRRTFRDVVRFEAGPCPEPCSRAQKSKMSAFNSHG-QETEKSMTKPNSLLMPINTFSGIIQ", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U6Q4-1", "uniprot_id": "PI3R6_MOUSE", "id": "Q3U6Q4-1", "name": "Phosphoinositide 3-kinase regulatory subunit 6", "aln": "----------------------------------------------------------------------MESSDVELDFQRSVQAVLRELN-TPNPALQSNQGMWRWSLHKKVERNPGKSSILVRILLRELEKAESEDGRRVIIPLLLTLMSVLTKATGIPEDLYHRAYTFCTRLLTLPAPYSTVALDCAIRLKTETAVPGTLYQRTVIAEQNLISELYPYQERVFLFVDPELVSASVCSALLLEIQAAQEQQTPEACMRHVVSHALQAALGEACHTGALNRKLQASSRRVLEYYFHAVVAAIEQVASEDSPSRLGHLEKMEEIYCSLLGPATTRRHCVGDLLQDRLPSIPLPSPYITFHLWTDQEQLWKELVLFLRPRSQLRLSADLDALDLQGFRLDRDLARVS---TDSGIERDLPLGSDELPDPSSSEMERAALQRKGGIKKRVWPPDFFMPGSWDGPPGLHRR----TGRPSGDGELLPGVSRVHTARVLVLGDDRMLGRLAQAYYRLRKRETKKFCLTPRLSLQLYYIPVLAPQVTGQDPEASRKPELGELASFLGRVDPWYESTVNTLCPAILKLAEMPPYLDTSRTVDPFILDVITYYVRMGTQPIYFQLYKVKIFTS-LSHDPTEDIFLTELKVKIQDSKSP--------KEGSSPRRRGAAEGTGAELSMCYQKALLSHRPREVTVSLRATGLVLKAIPAGDTEVSGFFHCTSPNAASATDCSCLHVSVTEVVKSSNLAGRSFTTSTNTFRTSSIQVQSQDQRLLTLWLDKDGRRTFRDVVRFEVSPCPEPCSRTQKSKTSALNSHG-QETEKNMAKPNSLLMPINTFSGIIQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5UE93-1", "uniprot_id": "PI3R6_HUMAN", "id": "Q5UE93-1", "name": "Phosphoinositide 3-kinase regulatory subunit 6", "aln": "----------------------------------------------------------------------MESSDVELDLQRSVQAVLRELS-TQAPALQSNQGMWRWSLHKKVERDPGKSPVLVRILLRELEKAESQDLRHVIIPLLHTVMYVLTKATGITEELYQRIYAFCTRLLTLPTPYCTVALDCAIRLKTEMAVPGTLYQRMVIAEQNLTNELYPYQERVFLFVDPELVSASVCSALLLEIEAAQAQQTPETCMRHVVSHALQAALGEACHAGALHRKLQASPRRTLEHYFHAVVAALEQMASEASPSREGHVERLEEIYCSLLGPAAGR--CGGDLVQERPPSIPLPSPYITFHLWTGEEQLWKELVLFLRPRSQLRLSADLEVLDLQGLRPDRELARVSVLSTDSGIERDLPTGADELPAPGSPEMERAGLQRKGGIKKRAWPLDFLMPGSWDGPPGLHRR----TGRPSGDGEMLPGVSRLHTARVLVLGDDRMLGRLAQAYHRLRKRETQKFCLTPRLSLQLYYIPVLAPE----KPAASRQPELGELATFLGRVDPWYQSNVNTLCPAIHKLAEMPPSLDTSRTVDPFILDVITYYIRMGTQPIYFQIYTVKIFFSDLSQDPTEDIFLIELKVKIQDSKFP--------KDGFSPRRRGVAEGPGAELSLCYQKALLSHRPREVTVSLRATGLILKAIPASDTEVSGSSHCPLP-AAPVTDHTCLNVNVTEVVKSSNLAGKSFSTVTNTFRTNNIQIQSRDQRLLTLSLDKDDQRTFRDVVRFEVAPCPEPCSGAQKSKAPWLNLHGQQEVEAIKAKPKPLLMPINTFSGIVQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQJ0-1", "uniprot_id": "A0A8M3AQJ0_DANRE", "id": "A0A8M3AQJ0-1", "name": "", "aln": "----------------------------------------------------------------MEETFGGVSPVVVSSLYHNIYSILRELDCKPQAGSASNKGMLRWTLHNRVDRNPSISVPLVRVLIKELEKAERIDSKIRIIPLLHTLVYTVLQSVFIPEDLYRRIYLCLKRLVLLPAPYCAIALDYARQMKMEQSAPGLLYQRRVIAEHNLCNDLYPLHEKVFVFVDPAVFPLSLVNALKAEVECGNPAGDPLMYKRRILLHTMLAGLGKQCQVDRLTQALEHSGE-DIELYFQDLVTILEQRAEDGASDDNQYNIRLQEIYQDILSPAKDP------SCQASQVETQLPGPEVSFHVWTKEDEIWNELVNYALMVPADRSSAYLDQDDLKRTS---VMSTVS---TDSGIEGDMPIS----------ELSSLMMDFQSGSDDQSRSLSFYRRPCVRWPKSGNRMTLMMEAIKGSGGCSLTKEERNLTARIVVLGDDRTLGRLAKTLYTIRKREARHLLLTKRVNMEMYYIPVTDQP---PLVQEGVPEDMLTLAGYLGSVDPWYDSNINGLGAMILKLAQMQSSQSESSQPNTFLLDIISYYTRVSQHPLHLPIYSVKICFSGLSSPSVEEVFVAQLMMDFPEVKHYRATFKDTIKGSVRHRKYNPQEYQGTVVSINYRKASISDREKEKGMSLTTNGMMISVLPS----------------CRVKSLHSLNISFQDMN--------PLRPSKPSIRAVSVNIRVLEKQTFTVCLDKDPQKTFKKVQSIEVSPCLDPGYCQQASTKSKYSLGEGGESLNKYLN-KTLTLPINTFCGSEQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. * .: :.: ::****. . .. **:** **:**::::*:*. * ***:*::****** * : ***** *:: .: ::. *.*:**:* * .**: **:**.::*** * ::* * :.** **** ****:** .:*** :*:**:**** :.. *: .** *::..: * *::: *:: *.**: *:.. * : *: * . :* **: :*: :** *.: :.. : :::*** .:*..* * . **.* ::**:** ::::*:*** : . * ** *: **: :: ** ****** *:* . *:. :: :.* ..: . .* . * . :* . ...* *. .* ***::****** :****:: : :****:::: ** *:.:::***** . :: ** :** *****:*.:* * . * ***:* . . * :.*:**:*:** *:. :*::: :*.*** . ** . *::*: :* :. : * * . *: . * *: :*: *:** :*.* :: :** :.*:::..:*: . . . .*::.. :: .: . . ::*: .:::: ::: :*: **** ::**:.* :*..** :* * *. . . * : :.* :*****.* *", "identical_positions": 236, "similar_positions": 242, "identity": "27.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120524-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q70EL4-1", "uniprot_id": "UBP43_HUMAN", "id": "Q70EL4-1", "name": "Ubiquitin carboxyl-terminal hydrolase 43", "aln": "MDLGPGDAAGGGPLAPRPRRRRSLRR--------LFSRFLLALGSRSRPGDSPPRP--QPGHCDGDGEGGFACAPGPVPAAPGSPGEERP-------PGPQPQLQLPAGDGARPPGAQGLKNHGNTCFMNAVVQCLSNTDLLAEFLALGRYR----------------AAPGRAEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGSQFQGNSQHDALEFLLWLLDRVHEDLEGSS-------RGPVSEKLPPEATKTSENCLSPSAQLPLGQSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPIPLRQTRFLSVTLVFPSKSQRFLRVGLAVPILSTVAALRKMVAEEGGVPADEVILVELYPSGFQRSFFDEEDLNTIAEGDNVYAFQVPPSPSQG---TLSAHPLGLSASPRLAAR-EGQRFSLS-------LHSES---KVLILFCNLVGSGQQASRFGPPFLIREDRAVSWAQLQQSILSKVRHLMKSEAPVQNLGSLFSIRVVGLSVACSYLSPKDSRPLCHWAVDRVLHLRRPGGPPHVKLAVEWDSSVKERLFGSLQEERAQDADSVWQQQQAH-QQHSCTLDECFQFYTKEEQLAQDDAWKCPHCQVLQQGMVKLSLWTLPDILIIHLKRFCQVGERRNKLSTLVKFPLSGLNMAPHVAQRSTSPEAGLGPWPSWKQPDCLPTSYPLDFLYDLYAVCNHHGNLQGGHYTAYCRNSLDGQWYSYDDSTVEPLREDEVNTRGAYILFYQKRNSIPPWSASSSMRGSTSSSLSDHWLLRLGSHAGSTRGSLLSWSSAPCPSLPQVPDSPIFTNSLCNQEKGGLEPRRLVRGVKGRSISMKAPTTSRAKQGPFKTMPLRWSFGSKEKPPGASV-------ELVEYLESRRRPRSTSQSIVSLLTG------TAGEDEKSASPRSNVALP--ANSEDGGRAIERGPAGVPCPSAQPNHCLAPGNSDG-PNTARKLKENAGQDIKLPRKFDLPLTVMPSVEHEKPARPEGQKAMNWKESFQMGSKSSPPSPYMGFSGNSKDSRRGTS---------ELDRP----LQGTLTLLRSVFRKKENRRNERAEVSPQVPPVSLVSGGLSPAMDGQAPGSPPALRIPEGLARGLGSRLERDVWSAPSSLRLPRKASRAPRGSALGMSQRTVPGEQASYGTFQRVKYHTLSLGRKKTLPESSF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BUM9-1", "uniprot_id": "UBP43_MOUSE", "id": "Q8BUM9-1", "name": "Ubiquitin carboxyl-terminal hydrolase 43", "aln": "MDPGVGNALGEGPPAPRPRRRRSLRR--------LLNRFLLALGSRSRSGDSPPRPPAQPSPYDGDGEGGFACAPGPAPASAGSPGPDRP-------PGSQP--QISSGDGARPPGAQGLKNHGNTCFMNAVVQCLSNTDLLAEFLALGRYR----------------AAPGRAEVTEQLAALVRALWTREYTPQLSAEFKNAVSKYGSQFQGNSQHDALEFLLWLLDRVHEDLEGSA-------HGLVSEQLPPEVSKISEDLRPSAAPTSLGPSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPIPLRQTRFLSVTLVFPSKSQRFLRVGLAVPILSTVAALRKMVAEEGGVPAEEVILVELYPNGFQRSFFDEEDLNTIAEGDNVYAFQVPPSPGLG---TLSAHPSGLSVSPRLPVR-DSQRFSGP-------LHSEN---RVVFLFCNLVGSGQQASRFGPPFLIREDRTISWAQLQQCILSKVRCLMRSEVSAQDLGTLFSIRVVGLSLACSYLSPKDNRPLCHWAVDRALHLRRPGGPPHVKLAVEWDSSVTERLFGSLQEERVQDADSVWRQQQAH-QQPSCTLDECFQSYTKEEQLAQDDAWKCPHCQVLQQGVVKLSLWTLPDILIIHLKRFCQVGERRNKLSTLVKFPLSGLNMAPHVARRSTNSKAGPGPWSSWKQPICLPTTYPLDFLYDLYAVCNHHGSLQGGHYTAYCRNSLDGQWYSYDDSTVEALREDEVNTRGAYILFYQKRNSIPPWSASSSMRGSTSSSLSDHWLMRLGSLNNSTRGSLLSWSSAPCPSMARVPDSPVFTNGVCHQDKGGVETRPLVRGVGGRSISMKASPASRSRHGPFKTMPLRWSFGHREKRPGASV-------ELVEYLESRRRPRSTSQSIVPLLTR------AAGGEETSASPRSDGTLP--AKSEDSGRAIGQGTTGVPLSSCHLNHHPALGSLDDSLHTARTRTGNVSQDIRLPKKFDLPLTVMPSVGDEKPARPEGQKMTPWKGSSQVGSQSSPPSPSTGLLRNFKDSGPGTLPKMKSKAAMEERAPDKDRGQGTFTLLKSVFWKKEHKRTVRTESSPPAPPISLGSDRLSPAAMNEQ-----ALRIRESPAKGLGNHMERDIRSAPSSLHLPRKASRPPRASTAGTSQRTIPGEQISYGTLQRVKYHTLSLGRKKSLPESSF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FD00-1", "uniprot_id": "E7FD00_DANRE", "id": "E7FD00-1", "name": "ubiquitinyl hydrolase 1", "aln": "MDKRDKKANKDSGSKSTKRTGKLFRRKSFKSVESLVSRILKSLGSLASGGETAERS--DAEDDDGGFGESAPCAGNSVKKEDSSTSSSQVRKSSSLTSRSSAKERMFSLYGDKTPGVLGLKNHGNTCFMNAVVQCLSNTDLLAEYLGLERYKRDVCHNGINGFIRNGNGQNEKGEVTERLAVLVRALWTFQYTPQLSAEFKMTVSKYGAQFRGNSQHDALEFLLWLLDRLHEDSTSVVPNGNNINKSKNKGQEGGDEKPGSDTLSPPQTQPGVRHSFVQEHFQAQYKSSLTCPHCLKQSNTFDPFLCISLPIPLRQTRPVCVTLVFSSKGQRYLRVGLAVPLFGSLACLRRMVADEGKIAPDQVILTEIYTTGFQRSFFDDDDLTIIAESDIIYAFQASPLYIRGGSARISGFHHSLPSSPYSSSGPEGHRLAASGALSSEFLNQTDGMLKVLLLVCNAAGAGQQAVRFGPPFLMREDRSVSWDQLQQSILSKLYYLMINGSQAHNFRVLFKIRVVGGSASYSYLNPQDGRPLFHPAVDRALKLCGSGGPPHVKLIVEWEHRIKDCLFGNIQEEVVKDSESVRAQQQHHVQQHSCTLDECFELYTKEEQLAPDDAWKCPHCKQLQQGTVQMSLWTLPDILILHLKRFRQVGERRNKLSTLVHFPLTGLDMGRHMVQRTSCARAPPG-WNKQAHRRPEASRYATDVLYDLYAVCNHHGGMHGGHYTAYCRNSVDGQWYTYDDSSVEPLQEGEVCTRAAYILFYQRRDAIPSWSASCSRQGSSSSSLSDHWLIRLNADEGISNSTSKVSNSSSAP-EPQTPHSPVIHKSANEDNRDVAEATPFVRSVRGQSMSMRYQ--SKSKTGSGKVLPLRWSFASKERRKPPSITSQNDNDELVEYLESGRRPRCTKEPIVSIVASPSQVKGHLREDDSLSSPSCCSSLNGVERSSSQGPDSPKVPEGQSRPTSDLN---AVSSVDSRAKKCSKTTRQEHERTQASKSLQGSPTALSTGNSTSHSRDSTLKRLRNPAAATSRIHPSQILMATGESRGKDGIHPVSSTSQLQDGCSKEVGHGKTLSSKSLTKLSLSNGTLNGKVVEVRKTGTVHKSTSKTNGRDTQVFSNTID------MKRAHSSSNIQNRLD---------MTLKRTLSLQRNGPLVPASNKGLAVDKSSYATLQRIKYSSTSLGRQRPVPESCF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** .* . . * : :** *..*:* :*** : *::. *. :. **. . .** ... .*.. .: . ... :: : * :.**. **************************:*.* **: . :.****:**.******* :********** :*****:**:*****************:*** . :. . : : . *: .. : : ****.******:********************:********** :.*****.**.**:********::.::*.**:***:** :..::***.*:*..********::**. ***.* :****..* * :*.. .*. ** . :.:*:: . *:. . :*::*.** .*:**** *******:****::** ****.****: ** . .::: **.***** * : ***.*:*.*** * ****.*:* .******** ***: :.: ***.:*** .:*::** *** * ** ********: ******** *********: **** *::**********:***** *************:***:**:*. *:.:*:: ..* * * . : .: *. *.************.::***********:*****:****:**.*:*.** **.*******:*::**.****.* :**:*********:**.: . :..: .*:..* .:.*.**:: :. .:::. *. :**.* *:*:**: *::: *. *.:******. :*: .*: ******** ****.*.:.**.::: ::. :** . :* .*.. * : . * . .:.. * * .. *. :.. . . : : : .:.:: . *.:.: . :* . * : :.* * . .. : : . ::* * . : : : .. . * .. : . . : .: .::: : * *. * ... *:: :. :: **.*:**:** : ****::.:***.*", "identical_positions": 494, "similar_positions": 322, "identity": "40.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120525-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "B5DEH9-1", "uniprot_id": "B5DEH9_RAT", "id": "B5DEH9-1", "name": "Ankyrin repeat domain-containing protein 6", "aln": "MSQQDAVAALSERLLIAAYKGQTENVVQLINKGAKVAVTKHGRTPLHLAANKGHLSVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEILTALIREGCALDRQDKDGNTALHEAAWHGFSQSAKLLVKAGANVLARNKAGNTALHLACQNSHSQSTRVLLLGGSRADLKNNAGDTCLHVAARYNHLSVVRLLLSAFCSVHEKNQAGDTALHVAAALNHKKVVKILLEAGADTTLVNNAGQTPLETARYHDNPEVALLLTKAPQILRFSRGRSLRKRRERLKEERRAQSVPRDEVAQSKG-SVSAGDTPSSEQAVPEKEEARRDCPPASQEPR-KDERRRKSRPEVSALSDPTPAADQQPGHQKNLHGHHHQKKKSRHRCWSPPPPHGFRAYQLYTLYRGEDGKVMQAPIKGCRCEPLINKLENQLEAAVEELRAELGTVQDKVNTKLGHMESKSQHQMCVLDKLMVERLSAERTECLNRLQQHAAAEKQEGE-KRQMSLVDELKSWCMLKIQNLELRLSGES--RTFRAKSTPSPSD------------SSPAVDQPVVAAGPGAASD---------------------------SSSQVVRPKDKALNATAVPRHQQELLPSDCTGSGLRKVKAP-------AASRLGDQQTG---SCVNRGTQTK-KSARGGQTKHRGQ-QPTASSPSGQQPSAASSD-----ARDASQALELTQYFFEAVSAQMEKWYERKIEEARSQASQKAQQDEATLKEHIRSLEEEVAKLRTKMHK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q69ZU8-1", "uniprot_id": "ANKR6_MOUSE", "id": "Q69ZU8-1", "name": "Ankyrin repeat domain-containing protein 6", "aln": "MSQQDAVAALSERLLIAAYKGQTENVVQLINKGAKVAVTKHGRTPLHLAANKGHLSVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEILTALIREGCALDRQDKDGNTALHEAAWHGFSQSAKLLVKAGANVLARNKAGNTALHLACQNSHSQSTRILLLGGSRADLKNNAGDTCLHVAARYNHLSVVRLLLNAFCSVHEKNQAGDTALHVAAALNHKKVVKVLLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQILRFSRGRSLRKRRERLKEERRAQSVPRDEVAQSKG-SVSAGDTPSSEQAVPQKEEARRDCPPASQEPR-KDERRRKSRPEVSALSDPTPAADQQPGHQKNLHSHHHPKKKSRHRCWSPPPPHGFRAYQLYTLYRGEDGKVMQAPIKGCRCEPLINKLENQLEATVEEIRAELGSVQDKVNAKLGQMESKTQHQMCVLDKLMVERLSAERTECMNRLQQHAAAEKQEGE-KRQMSLVDELKAWCMLKIQSLELRLSGES--RTFRAKSTPPPSD------------STPAVDQPVVAAGPGAASD---------------------------SSSQVVRPKDKALNASAAHSHQQELPPSDCTGSGLRKIKAP-------GASRC-DQQTG---SCVNRGTQTK-KSGRSGQTKHRGQ-QPTASSPSGQQPSAASSD-----VRDASQALELTQYFFEAVSAQMEKWYERKIEEARSQASQKAQQDEATLKEHIRSLEEELARLRTKVQK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y2G4-2", "uniprot_id": "ANKR6_HUMAN", "id": "Q9Y2G4-2", "name": "Ankyrin repeat domain-containing protein 6", "aln": "MSQQDAVAALSERLLVAAYKGQTENVVQLINKGARVAVTKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLTKAPQVLRFSRGRSLRKKRERLKEERRAQSVPRDEVAQSKG-SVSAGDTPSSEQAVARKEEAREEFLSASPEPRAKDDRRRKSRPKVSAFSDPTPPADQQPGHQKNLHAHNHPKKRNRHRCSSPPPPHEFRAYQLYTLYRGKDGKVMQAPINGCRCEPLINKLENQLEATVEEIKAELGSVQDKMNTKLGQMENKTQHQMRVLDKLMVERLSAERTECLNRLQQHSDTEKHEGE-KRQISLVDELKTWCMLKIQNLEQKLSGDS--RACRAKSTPSTCE------------SSTGVDQLVVTAGPAAASD---------------------------SSPPVVRPKEKALNSTATQRLQQELSSSDCTGSRLRNVKVQTALLPMNEAARS-DQQAG---PCVNRGTQTK-KSGKSGPTRHRAQ-QPAASSTCGQPPPATGSEQTGPHIRDTSQALELTQYFFEAVSTQMEKWYERKIEEARSQANQKAQQDKATLKEHIKSLEEELAKLRTRVQKEN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PES1-1", "uniprot_id": "A0A8M9PES1_DANRE", "id": "A0A8M9PES1-1", "name": "", "aln": "------------------------------------------------------------------------MGHQTALHRAAVVGNRDAVSALIHGGCALDLQDKEGNTALHEVSWHGFSACVKLLVKAGADVNLKNKVGNSPLHLACQNGHSQTAQVLLLGGCMPDSKNNAGETCLHFAARYNHLAIIKMLLGSFCSVTEKNQTGDTALHVAAALNHKKAVSLLLEAGADANIKNNTGQTALDKARDNNNRELAILLAKSNQVQRYARGKTVRKRRDVSRAQRKTQSLPRVHKPRKKDDSEAAEDSINSDQAFQRIQPEHRAATLSP------DNRRKNTSP------------GRTPVLLREYDLYERGVKPS-SLSSPDQHQTPAKAFQLYTLYRDTDGQIKQAPAKDCHCKPIIKALEKKLKATEMEMRTEIHTIQEEINCRLGRIEQKNKHQIKVLEKLTQERVSAERMECHYRINQRATLERMEGQRKQQAAASNAVKSWCMSKIEDLEVRMPETQYYKLLRSPSADSELEGLPLLSLVSEESSSSLATYVNVLPTPGASHKSLEFEDTLGKRYLKIKQNGSSDDYHNITAQPMVKHKPLSRSLATADLQWQRSELQEAEISKHRSDKGHELCDSSTSSSRSTSSKTFNDSDSISRSAWKHSKHLKDRIKAHRAQTQQSTTVNTLEVFSQRPAEATFTQERANLHAVEVTQRFFETVSTQLERWYERKILETQRSAEHKALQDRSRLMEKISSLEEELRRLRTDHSTNT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.*******:**** : ::***: ***** ***:*******.:***** ..***:****:* :**.**:.*******.***::::***.*. .* *****:****.*******:::::** :**** ****:***************...:*******:.: **:***.*:.** ::* *:*:**:*: *: *::**:::**:*: : :*::**:** . .:.*. * :* *: .*:**. . : :. :. *:**::: * .: * :: . :.: * . . . :*:*******. **:: *** :.*:*:*:*: **::*:*: *:::*: ::*:::* :**::*.*.:**: **:** **:**** ** *::*:: *: **: *:* : : :*:*** **:.** ::. . : *: *: . : *:. . * . *.*: . :: :*: * : . ::. *. .:. * *. * ::* ..:: .:.*.: .: * :. . **.* * ::: : . :: * :*:*:** ***:**:*:*:****** *:: .*.:** **.: * *:* *****: :*** . ", "identical_positions": 261, "similar_positions": 213, "identity": "33.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120525-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZW33-1", "uniprot_id": "D3ZW33_RAT", "id": "D3ZW33-1", "name": "", "aln": "---------------MSVDEKPDSPMYVYESTVHCANILLGLNDQRKKDILCDVTLIVERKEFRAHRAVLAACSEYFWQALVGQTKDDLVVSLPEEVTARGFGPLLQFAYTAKLLLSRENIREVIRCAEFLRMHNLEDSCFSFLQTQLLNREDGLFVCRKDSACQRPQEDHGNSAGEEE-EEEETMDSETARMACATDQMLPDPISFEATAIPVAEKEEALLPESEVPTDTKENSEKGALTQYPRYKKYQLACTKNVYSAASHGTSGFAGTFSEESPGNSLKPGLSVGQIKSEPPNEETEEESITLCLSGDETDIKDRPGDVEMDRKQPSPAPPPGTPTGATSLDRSRSVSSPSCLRSLFSIAKGVESTGLPSTSQQHFVRSSACPFNKGISQGDLKTDYTPLAGNYGQPHVGQKDVSNFAMGSPLRGPGPETLCKQ--EGELDRRSVIFSASTCDQPNTPVHSYSSVSSLDKDLSEPVPKSLWVGAGQSLPSSQAYSHGGLMAD-HLPGRIRPNTSCPVPIKVCPRSPPLETRTRTSSSCSSYSYAEDGSGGSPCSLPLCEFSSSPCSQGARFLATEHQEPGLMGDGMYNQVRPQIKCEQSYGTNSSDESGSFSEADSESCPVQDRGQEVKLPFPVDQITDLPRNDFQMMIKMHKLTSEQLEFIHDIRRRSKNRIAAQRCRKRKLDCIQNLECEIRKLVCEKEKLLSERNQLKVCMGELLDNFSCLSQEVCRDIQSPEQIQALHRYCPVLIPMDLPGAS-VNPPPLGVEQSLAPSQCAVGGSVPCCLEPGAAPPGLPWVPSNTSENCTSGRRLEGSDPGTFSERGPPLEARSQSVTVDFCQEMTEKCTTDEQPRKDYA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97303-1", "uniprot_id": "BACH2_MOUSE", "id": "P97303-1", "name": "Transcription regulator protein BACH2", "aln": "---------------MSVDEKPGSPMYVYESTVHCANILLGLNDQRKKDILCDVTLIVERKEFRAHRAVLAACSEYFWQALVGQTKDDLVVSLPEEVTARGFGPLLQFAYTAKLLLSRENIREVIRCAEFLRMHNLEDSCFSFLQTQLLNREDGLFVCRKDSACQRPQEDHGNSAGEEE-EEEETMDSETARMACATDQMLPDPISFEATAIPVAEKEEALLPESEVPTDTKENSEKGALTQYPRYKKYQLACTKNVYSAPSHGTSGFASTFSEDSPGNSLKPGLPMGQIKSEPPSEETEEESITLCLSGDETDIKDRPGDVEMDRKQPSPAPTPSTPTGAACLDRSRSVSSPSCLRSLFGITKGVESTGLPSTSQQPLVRSSACPFNKGISQGDLKTDYTPLAGNYGQPHVGQKDVSNFAMGSPLRGPGPETLCKQ--EGELDRRSVIFSASACDQPNTPVHSYSAVSNLDKDLSEPVPKSLWVGAGQSLPSSQAYSHSGLMAD-HLPGRIRPNTSCPVPIKVCPRSPPLETRTRTSSSCSSYSYAEDGSGGSPCSLPLCEFSSSPCSQGARFLATEHQEPGLMGDGMYNQVRPQIKCEQSYGTNSSDESGSFSEADSESCPVQDRGQEVKLPFPVDQITDLPRNDFQMMIKMHKLTSEQLEFIHDIRRRSKNRIAAQRCRKRKLDCIQNLECEIRKLVCEKEKLLSERNHLKACMGELLDNFSCLSQEVCRDIQSPEQIQALHRYCPVLIPMDLPGAS-VNPPPVGVEQSLAPSPCAVGGSVPCCLEPGAAPPGLPWVPSNTSENCTSGRRLEGSDPGTFSERGPPLEARSQSVTVDFCQEMTEKCTTDEQPRKDYA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYV9-1", "uniprot_id": "BACH2_HUMAN", "id": "Q9BYV9-1", "name": "Transcription regulator protein BACH2", "aln": "---------------MSVDEKPDSPMYVYESTVHCTNILLGLNDQRKKDILCDVTLIVERKEFRAHRAVLAACSEYFWQALVGQTKNDLVVSLPEEVTARGFGPLLQFAYTAKLLLSRENIREVIRCAEFLRMHNLEDSCFSFLQTQLLNSEDGLFVCRKDAACQRPHEDCENSAGEEEDEEEETMDSETAKMACPRDQMLPEPISFEAAAIPVAEKEEALLPEPDVPTDTKESSEKDALTQYPRYKKYQLACTKNVYNASSHSTSGFASTFREDNSSNSLKPGLARGQIKSEPPSEENEEESITLCLSGDEPDAKDRAGDVEMDRKQPSPAPTPTAPAGAACLERSRSVASPSCLRSLFSITKSVELSGLPSTSQQHFARSPACPFDKGITQGDLKTDYTPFTGNYGQPHVGQKEVSNFTMGSPLRGPGLEALCKQ--EGELDRRSVIFSSSACDQVSTSVHSYSGVSSLDKDLSEPVPKGLWVGAGQSLPSSQAYSHGGLMAD-HLPGRMRPNTSCPVPIKVCPRSPPLETRTRTSSSCSSYSYAEDGSGGSPCSLPLCEFSSSPCSQGARFLATEHQEPGLMGDGMYNQVRPQIKCEQSYGTNSSDESGSFSEADSESCPVQDRGQEVKLPFPVDQITDLPRNDFQMMIKMHKLTSEQLEFIHDVRRRSKNRIAAQRCRKRKLDCIQNLECEIRKLVCEKEKLLSERNQLKACMGELLDNFSCLSQEVCRDIQSPEQIQALHRYCPVLRPMDLPTASSINPAPLGAEQNIAASQCAVGENVPCCLEPGAAPPGPPWAPSNTSENCTSGRRLEGTDPGTFSERGPPLEPRSQTVTVDFCQEMTDKCTTDEQPRKDYT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HR31-1", "uniprot_id": "A0AC58HR31_DANRE", "id": "A0AC58HR31-1", "name": "", "aln": "MIGSAGSRASGSEQGMSMEEKPDTPMYVYESTVHCANILLCLNEQRQQDVLCDVTVLVEGREIRAHRAVLAACSQYFSLLLRGPTEHEPLISLPMKITEKGFAPLLQFAYTAKLLLNRDNIQDVMRCAEFLGMHNLEDSCFRFLEAQMKSELEG----TSPPSNQTLLQNHHNNKTEDA--KVQLRDSKPPLFGSRLH----------------SETEQMKMHQSDQPQPFD-------LPRYPKYRKYHQVHAKHNTSTSSHSSTSSLQGSLQDTVTSSNARGLDLSKVKAEPVNG---EVSVPLDLSELEQNGPVRGKVIEMDIEMEFDGRQLSSTP----NEFPASKRSPVCLRSLVKKEVSSSDHCL-STDLQLSSRTSPLREQQVVTVQEQQVDFQ---KDY-QAFIGGLSSKKLPDGVSLKSLSLERICSQDPEQENDRKSVIFSSRGP-YHLAPTHSYPDESCLGQET----PEDLWAGSSQSFPCTQTLSPTSSSQDPSLPYRRHPKSSCPVPIKMCSRSTRADSHVRTSSSCSSYSYAEDGSGGSPSSLPQFELSTSPCSTMARCLALEHREHSTSGP-------PKIKCEKSYDTNSSDESGSFSDGDSESFATKERTQEVKLPFSVDQITELPRNDFQLMIKMHKLSSDQLDFIHDMRRRSKNRIAAQRCRKRKLDCIQNLEREIHKLVCERQKLLTERSQLKTCMGELWENFSFLSKEVCREEQRTPRSQYNPHTDPVLSGTELQISL--------IPNSKDISDCQT-----------TQPPHLHRR---------ADRDTEPSQENTASIRSDASQTGSSSVTIDFCQEMTEKCTTEELPERN--", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **::***.:***********:**** **:**::*:*****::** :*:***********:** * * *:.: ::*** ::* :**.*************.*:**::*:****** ********* **::*: . :* . .: * :: *. *: : : **:.. :.. . :*.*: : :.: * . *.:**:*:**: . :*: .:.**.::. ::. .* ** .::*:** . * *:.* ** * : * :*** : . :.. : . * ** *****. . . * **. * *:.. :: :: : :.*: :* *..:* . .::. * .*:. . * :*.* * * **:*****: :..***. * *.:: *:.**.*:.**:*.:*: * . * ** * :*::*******:*.**. :::.********************.*** *:*:**** ** ** **:* . * *:****:**.***********:.**** ..::* *******.*****:*******:*******:*:**:****:************************* **:*****::***:**.:**.***** :*** **:****: * . : * : *** :* : :. * * . : ** :.* * :: .* * *. . :. *.:**:*******:****:* *.:: ", "identical_positions": 361, "similar_positions": 208, "identity": "42.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120529-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PCD5-1", "uniprot_id": "RFWD3_HUMAN", "id": "Q6PCD5-1", "name": "E3 ubiquitin-protein ligase RFWD3", "aln": "MAHEAM---------EYDVQVQLNHAE------QQPAPAGMASSQGGPALLQPVPADVVSSQGVPSILQPAPAEVISSQATPPLLQPAPQLSVDLTEVEVLGEDTVENINPRTSEQHRQGSDGNHTIPASSLHSMTNFISGLQRLHGMLEFLRPSSSNHSVGPMRTRRRVSASRRARAGGSQRTDSARLR--APLDAYFQVSRTQPDLPATTYDSETRNPVSEELQVSSSSDSDSDSSAEYGGVVDQAEESGAVILEEQLAGVSAEQEVTCIDGGKTLPKQPSPQKSEPLLPSASMDEEEGDTCTICLEQWTNAGDHRLSALRCGHLFGYRCISTWLKGQVRKCPQCNKKARHSDIVVLYARTLRALDTSEQERMKSSLLKEQMLRKQAELESAQCRLQLQVLTDKCTRLQRRVQDLQKLTS-HQSQNLQQPRGSQAWVLSCSPSSQGQHKHKYHFQKTFTVSQAGNCRIMAYCDALSCLVISQPSPQASFLPGFGVKMLSTANMKSSQYIPMHGKQIRGLAFSSYLRGLLLSASLDNTIKLTSLETNTVVQTYNAGRPVWSCCWCLDEANYIYAGLANGSILVYDVRNTSSHVQELVAQKARCPLVSLSYMPR-AASAAFPYGGVLAGTLEDASFWEQKMDFSHWPHVLPLEPGGCIDFQTENSSRHCLVTYRPDKNHTTIRSVLMEMSYR-LDDTGNPICSCQPVHTFFGGPTCKLLTKNAIFQSPENDGNILVCTGDEAANSALLWDAASGSLLQDLQTDQPVLDICPFEVNRNSYLATLTEKMVHIYKWE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CIK8-1", "uniprot_id": "RFWD3_MOUSE", "id": "Q8CIK8-1", "name": "E3 ubiquitin-protein ligase RFWD3", "aln": "MAEVAVGQASDLVPSEMDHEVIYSHLQGPLEGTIEPATPTEVVSNG--APLQPAPAELANSQGG-AHVQPAPAEVVSSQDGLPTLQPLPPASIDLTEEVQPSEENMEVVNPGTSEEPSQGSGANPTAGAARSVSMNNFISGLQRLHNMLELLRPPPADHSVGPIRTRRRMAPILRARAGESQRQDNGRYVPHTPLYAYFQVSRSQPYPLPAAHDSETRNPP-------SGTDSDSDGSAEDEEVVVQAEEPEANIPEQ--GVIATDQEATSVTGDDAVPKE-SPQKPNMLS---AMEDEEGETCTICLEQWTNAGDHRISALRCGHLFGFRCISKWLKGQTRKCPQCNKKAKHSDIVVIYARSLRALDTSEQERMKSDLLNEQMLRKQAELESAQCRLQLQVLIDKCTKLNSRVQDLEKFVVRHQNSAAQQCSRSKALCGKCLSSSQS--PGKYSSEKTFTISQTGKCRILAYCDGLSCLVASQPSPQASFLPGFGVKMLSTANMKSSQYIPMHNKQIRGLSFSSQSKGLLLSASLDCTIKLTSLETNTVVQTYNTGRPVWSCCWCLDENNYVYAGLASGSILIYDLRNTNTYIQELVPQKARCPLVSLSYLPK-AAVAAFPYGGVLAGTLENASFWELKSDFSHKPHVLSLEPGGFVDFQTESSTRHCLVTYRPDKSHNTVRTVLLEMSYK-LDDAGEPVCSCLPVQTFLGGPTCKLLTKSAIFQSPENNGNVLVCTGDEASQSTLLWNAGSGLLLQNLKAGEPVLDICPFETNQNSYLATLTEKTVHMYKWE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "X1WE22-1", "uniprot_id": "X1WE22_DANRE", "id": "X1WE22-1", "name": "RING-type E3 ubiquitin transferase", "aln": "------------------------------------------------------------------------------------------------------MEDMEVVMVSES-------------GSSTEEEENDVAASVPEDRSRLPLRRAP-----------RRRQIISQRPHAERVRRIQTLLQNTHNPPDTHNPPD-TRTDPEPASSDSAD----------QSRVQSTAETSSPAGPSVPAAAEAPAVELKT-------EVEASSDSSGSAAASPAGAAD---------EADTEGESCSICFEPWTTAGEHRLAALRCGHLFGYVCISRWLTGGGNKCPQCNKPAKKTQIIFLYARRLKALDNTEEVRLKSRLELEQGSRRMEQLEVAQCRQQLQLMVDENTRLRKEVEELRRWKAQASAGSSQAAS---------LSSSQRQDSGHYVFSKAVLVSQTGGSRVLAHCEPLGCLLASQPSPQATLMPGFGVKKISTATLKASQYVHIHSKQIRGLAFSQQQDGLLLSAALDNTIKLTSLMTNTVVQAYNTGRPVWSCCWCHDNNNYIYAGLSNGSVLVYDTRDTSTHVQELRPLRSSCPVVSLSYIPHSSTSSSFPCGGVIAGTLEGGCFWERHNDNTHTPHILPLESGNCTHIQAEAESRHCLVTYRPGRLNPSLRCVLMELSRTPQVDLQSSVCSCSPVQTFSAGSSCKLLTKNCVFRSPAGGGAALVCAGDEATNSTMVWDAGTGALLQKMPADLPVLDICPFEANQSSFLASLTEKMIKVYKWE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :* : * :: . .:. :.: . :. * : *.. *** *.:* :* :. * :: . ::. .:: ** * :* :: *: * * *. * : : *.:. ...: .. .. . : **::*:**:* **.**:**::*********: *** **.* .******* *::::*:.:*** *:***.:*: *:** * ** *: :** **** ***:: *: *:*. .*::*.: . * .*** :* .*:. :**:* .*::*:*: *.**: *******:::****** :***.:*:***: :*.******:**. ******:** ******* ******:**:********** *: **:****:.**:*:** *:*.:::*** . :: **:*****:*: :: ::** ***:*****...*** : * :* **:*.**.*. .:*:* .:*********.: : ::* **:*:* * ..:*** **:** .*.:******..:*:** ..* ***:****::*:::*:*.:* ***.: :. *********.*:.*:**:**** :::****", "identical_positions": 279, "similar_positions": 194, "identity": "35.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120529-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9W0F8-1", "uniprot_id": "Q9W0F8_DROME", "id": "Q9W0F8-1", "name": "rhomboid protease", "aln": "----------------------------------------------------------------------------------------------------------MLLLSGAPSQGR----RPKNR-----PLIGTVEEGEMPPSTVLQMPPAPLSSKSGLVLGVCCDQLMAVQPVQR-----------ASGAAATKSNSPDWGNHRAKHH--EGSAAPFKWIPPFFIILATLLEVLVFLWVG----------------ADPPEDSLLVYRPDQRLQLWRFLSYALLHASWLHLGYNVLTQLLFGVPLELVHGSLRTGVIYMAGVLAGSLGTSVVDSEVFLVGASGGVYALLAAQLASLLLNFGQMR--HGVIQLMAVILFVFCDLGYALYSRELAMHQLQTRPS-------------VSYIAHMTGALAGISVGLLLLRQLDGGLRPRPLRWLALGVWCIFSAFGIAFNLVNTVTAQLLAEEEGQVIRQHLMNDLGMG", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P20350-1", "uniprot_id": "RHOM_DROME", "id": "P20350-1", "name": "Protein rhomboid", "aln": "----------------------------------------------------------------------------------------------------------MENLTQNVNETKVDLGQEKEK-----EASQEEEHATAAKETIIDIPAACSSSSNSSSYDTDCSTASSTCCTRQ-----------GEHIYMQREAIPATPLPESEDI--GLLKYVHRQHWPWFILVISIIEIAIFAYDRYTMP-----AQNFGLPVPIPSDSVLVYRPDRRLQVWRFFSYMFLHANWFHLGFNIVIQLFFGIPLEVMHGTARIGVIYMAGVFAGSLGTSVVDSEVFLVGASGGVYALLAAHLANITLNYAHMK--SASTQLGSVVIFVSCDLGYALYTQYFDGSAFAKGPQ-------------VSYIAHLTGALAGLTIGFLVLKNFGHREYEQLIWWLALGVYCAFTVFAIVFNLINTVTAQLMEEQ-GEVITQHLLHDLGVS", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "O75783-1", "uniprot_id": "RHBL1_HUMAN", "id": "O75783-1", "name": "Rhomboid-related protein 1", "aln": "-----------------MGRVEDGGTTEELEDWDPGTSALPAPGIKQGPREQTGTGPLSQKCWEPEPDAPSQPGPALWSRGRARTQALAGGSSLQQLDPENTGFIGADTFTGLVHSHELP--LDPAKLDMLVALAQSNEQ----GQVCYQELVDLISSKRSSSFKRAIANGQRALPRDG----PLDEPGLGVYKRFVRYVAYEILPCEVDRR--WYFYRHRSCPPPVFMASVTLAQIIVFLCYGARLN-----KWVLQTYHPEYMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGLLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLRFSPPLPASGPQP--------------SFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAVFWNVF-AYDLLGAHIPPPP-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VC82-1", "uniprot_id": "RHBL1_MOUSE", "id": "Q8VC82-1", "name": "Rhomboid-related protein 1", "aln": "-------------------------------------------------MDRSSLLQLIQE---------------------------------QQLDPENTGFIGADTFAGLVHSHELP--LDPTKLDMLVALAQSNER----GQVCYQELVDLISSKRSSSFKRAIANGQRALPRDG----LLDEPGLSVYKRFVRYVAYEILPCEVDRR--WYFYRHRTCPPPVFMASVTLAQIIVFLCYGARLN-----KWVLQTYHPEYMKSPLVYHPGHRARAWRFLTYMFMHVGLEQLGFNALLQLMIGVPLEMVHGVLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLRFSPPLPASGPQP--------------SFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFLLFAIFWNVF-AYDLLGADIPPPP-------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O88779-1", "uniprot_id": "RHBL1_RAT", "id": "O88779-1", "name": "Rhomboid-related protein 1", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FMHVGLEQLGFNALLQLMIGVPLEMVHGVLRISLLYLAGVLAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMRCPYKLLRMVLALVCMSSEVGRAVWLRFSPPLPASGPQP--------------SFMAHLAGAVVGVSMGLTILRSYEERLRDQCGWWVVLLAYGTFL------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M6YY16-1", "uniprot_id": "A0A8M6YY16_DANRE", "id": "A0A8M6YY16-1", "name": "Rhomboid-related protein 1", "aln": "-------------------------------------------------MDRSSLFQLIQE----------------------------------QLDPEQTGFITVENFTSLAEHHELQ--LDPSKLEMLLALVQSNEH----GHVCYQELIELLNSKRSSSFRRAIANGRRTLQREI----LLDETGLGVYKRFVRYVAYEILPCETDRR--WYFHQNRLCPPPVFMAVITIVQIMVFMCYGVMLN-----KWVLQTYQPDFMKSPLVYHPGHRAQIWRFFSYMFMHVGLEQLGFNALLQLMIGVPLEMVHGILRISLLYMAGVIAGSLTVSITDMRAPVVGGSGGVYALCSAHLANVVMNWAGMKCPYKLLRMILALVCMSSEVGRAVWLRFSPPLPSSGPQP--------------SFMAHLSGAVVGISMGLLILRSYEESLHKQCSWWVLIFSFVTFLLFAIFWNIF-AYELLGVQIPPPP-------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0E9-1", "uniprot_id": "Q9W0E9_DROME", "id": "Q9W0E9-1", "name": "", "aln": "MWPGSERGSSRALEIPTSQQNAGGSSQQETLADIEHISTIAGSLASIGSLSHTQMRYQCTNDAGYDTEHTSLNSDFDEAELRRELLRDKWKLLFDMFDPEGFGEISVEEFLEALKSPEFLSQVPMNKRELLLERAKKAKLPTGPGYVTFQDFVNVMSGKRTRSFKCAVHHRDREVCSENDFQLVLNEP--PLFRKMVHAVAMEILPEERDRK--YYADRYTCCPPPFFIILVTLVELGFFVYHSVVTG-----EAAPRGPIPS--DSMFIYRPDKRHEIWRFLFYMVLHAGWLHLGFNVAVQLVFGLPLEMVHGSTRIACIYFSGVLAGSLGTSIFDPDVFLVGASGGVYALLAAHLANVLLNYHQMR--YGVIKLLHILVFVSFDFGFAIYARYAGDELQLGSSSEFLAIDQAETAGAVSYVAHLAGAIAGLTIGLLVLKSFEQKLHEQLLWWIALGTYLALVVFAIAFNIMNGFAMFNIRVEKIRVT-ETIFNDFQV-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VYW6-1", "uniprot_id": "Q9VYW6_DROME", "id": "Q9VYW6-1", "name": "", "aln": "------------------------------------------MPVKTVNRQQSQTPAQQLQLQQQRDVENGLYPTIPAERRSPPSRPQTLRQDTIDMEEIPLNQTNSQEPEDRRKMHEIFDKHDSDRDGLINTHELKELISDGYCRDIPAYIADQILKRSDQDNDGHLDFEEFYAMSLR-----HKWMVRNMLTRYCRYVVPPPKPLEGDEPDGAYEKQMSICPPPLTMVLFSIIEIIMFLVDVIHFQDDPNYQDRIGESTSGPAATLFIYNPYKRYEGWRFVSYMFVHVGIMHLMMNLIIQIFLGIALELVHHWWRVGLVYLAGVLAGSMGTSLTSPRIFLAGASGGVYALITAHIATIIMNYSEME--YAIVQLLAFLVFCFTDLGTSVYRHLTDQHDQIG------------------YVAHLSGAVAGLLVGIGVLRNLEVRRWERILWWVAVIVYFALMTTGIIIHVFVPDYFPKQEYN----------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q86BL6-1", "uniprot_id": "Q86BL6_DROME", "id": "Q86BL6-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------MSAQVESNGASESNNNCVKDVRLLLLPENSTDSDGNPASVAFSAESHK---------------KFIDDLTRTIDVGHVRRK--------RLWRVPWFILLMSFVQISLHWIASECMQ------------------KVLIFKPEWNVEYWRLLTYMLLHSDYWHLSLNICFQCFIGICLEVEQGHWRLAVVYMVGGVAGSLANAWLQPHLHLMGASAGVYAMLGSHVPHLVLNFSQLS--HRFARIASLLILLLSDVGFTTYHFCHNHNRNPRTSL----------------EAHIGGGVAGILCGFIVYRRLQPANQKAIYF-----------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .:* . :* * * .:*: **: : * . :*: * .***: : . : *.*.****: :::. : :*: : :: :: :.* : : **: *.:.*: *: : : ", "identical_positions": 26, "similar_positions": 44, "identity": "5.2%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120601-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NHW6-1", "uniprot_id": "OTOSP_HUMAN", "id": "Q8NHW6-1", "name": "Otospiralin", "aln": "MQACMVPG-LALCLLLGPLAGAKPVQEEGDPYAELPAMPYWPFSTSDFWNYVQHFQALGAYPQIEDMARTFFAHFPLGSTLGFHVPYQED-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R448-1", "uniprot_id": "OTOSP_MOUSE", "id": "Q8R448-1", "name": "Otospiralin", "aln": "MQACVLWW-LALGMLLGIPAGAKPMPEEADPHTQPPAMPYWPFSTSDFWNYVQYFQTQGAYPQIEDMARTFFAHFPLGSTLGFHVPYQED-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A286Y9F3-1", "uniprot_id": "A0A286Y9F3_DANRE", "id": "A0A286Y9F3-1", "name": "", "aln": "MKWSMFFCVFLLCFLANNLSDARVIP-EGVPYENPPAVPYWSYSTSDFWNYVEYFRSIGAYDQINQLARTFFAHQHLGDTLGYEVAEQHEH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: .:. : * :* . :.*: : *. *: : **:***.:*********::*:: *** **:::******* **.***:.*. *.: ", "identical_positions": 40, "similar_positions": 30, "identity": "43.96%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120608-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A1B0GWU0-1", "uniprot_id": "A0A1B0GWU0_RAT", "id": "A0A1B0GWU0-1", "name": "Centriolin", "aln": "MKKGSE-RKLSKAKMPVSSHFPGPSSLRSSMRSRSLSPLIGSETPPFHPGGQCPAQAELTDENTMPLESQQHKGADPYVGVRYITEALIKKLTKQDNLALVKSLNLSLSKDGGKKFRYIENLEKCVKLEVLNLSYNLIAKIEKVDKLLRLRELNLSYNKISKIEGLENMCNLQKLNLAGNEIEHIPGWFSKKLKSLRVLNLKGNKISSLQDVSKLKPLQDLTSLTLIDNPVVALPHYLQFIIFHLRSLESLEGQPVTTQDRQEAFERFSLEEIERLEKDLEKKTVETEELKNKQTKFLEEIKHQDKLNKSLKEEAMLQKQSCEELESDLNTKKEL-------------LKQKTVELTRACQKQYELEQELAFYKIDAKFEPLNYYPSEYAEMDKSPDESPYIGKSRYKRNMFATETYIVSDAQAVQVRKMVPDGGQLRHEHAP-RAQAPPDVQLEDTGKQIVAAQTRLSELHHEIEAAEQKVLRATQEFKQLEEAIRQKKISEAEKDLLLKQLSGRLRHLNKLRQEALDLEAQLEKQRKEIAEKHEEINSAQLATDLLDSKDPKQSHMKAQKRGKEQQLDIMNKQYTQLESRLDEILCRIATETEEIKDLEQQLTDGQIAANEALKKDLEGVISGLQEYLGTIKGQAAQAQNECRKLQDEKETLLQRLTEVKQEKDELEIVAMDAENMRKELAELENALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAETSQLKQELENLVRRTQLEQSVLQTELEKERQSLRDALGKAQSSEEKQQENSELRAQLKQLQDDNSLLKKQLKDFQSHLNHVVDGLIHPEEVAARVDELRKRLKLGAGEMRIHSPSDVLGKSLADLQKQFSEILARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFK-QACERALEARIKFDKRQHNARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEEKERILAQLQELEKKKRREDARSQEQFLGLDTELKSLKKAVAASDKLAAAELTIAKEQLKSLHGTVMRINQERAEELQEAERSSREAMQAAKDLSRAEAEIELLQHLLREREGQFRDEMENAHVGSKGANLQLLEIEALKEAMAKQRAEITRLRDVLNLTGTGKKGGIENVVEEIAELRHAVSAQNEYISSMADPVQRQGCWYFMPPPPSSKVSSHSSQATKDSGLGLKCTASTPLRSQQAGQQEEKGSSGPLPASGYWVYSPIRSTPHKSFSKREDADNGGDSQEESGLDDQEDPPFVPPPGYIMYTVLPDGSPVPQGVALYAPSPPLPHSSHPLTPGTVVYGPPPAGAPIIYGPPPANFAVPLISMGVQHCNIPEHRDLENEVSRLEDITHHLKSKHQEERWLKTSRQHPEKEVEELHRNIDDLVQEKKELELEVEELHRTVERHQQRRDFIDGNVENLMTELEIEKSLKHHEDIVDEIECLEKTLLKRRSELREADRLLAEAESELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAEVNEDHHLQVLKESESLLQAKRAELETLKSQVTSQQQELAVLDSQLGHRREELLLLQDSLTQAKADLQEALTLGETEVAEKCSHIREVKSLLEELSFQKGELNVHISERRTQLTLIKQEIEKEEENLEVVLQQLSKHKTELKNVADILQLETNELQSLKLQHDQKVVELEKTQVDLLEGKLELESLQQTAQQQRRELERQRQLLERDRRETERVRAETQALQSCIECLNKEKEHLQEQCESWEKKSSHAKRVLAATEESNNTEQSKLGQLEVSVRKLQQELELLSQDKLALHSDSAQEQQQLQDKREALNSLQKELENTQDHLNLAKQDLMHTTKCQSALLSEQAQLQKDVSQWTARLESCQKETETKEQQLQELQDEIRESKLQLDQQEMVFQKLQKERESEEQKLVASIVSLEQQQGQLERELMDQKSKLEWLLTDVSAAEGRLRTLQKEERCTESLEKMLSQAKQQLSEREQQLMEKSGDLLALQKEADGMRADFSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLEKNLLEQKQENSCMQKEMATIELVAQDNHERARRLMKELRQMQQEYLELKKQVANQKDFERRQMEVSNAMRTLKSEVKDEIRTSLRNLNQFLPDLPADLTAILERDDNLR-ELESVKENFPFTTNERIFEEKSNFPQVHIMDEHRRGEALRERLRHREDHLKAQLRDSMSKQAEVLIKGKRQTEGTLHSLRRQVDALGELVTSTSVDSAPSPSLSHLESSLVEDSQHGHSQSSFQVLQVPSE-PNIYRH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AL36-1", "uniprot_id": "CNTRL_MOUSE", "id": "A2AL36-1", "name": "Centriolin", "aln": "MKKGSE-RRLSKAKMPLSSHFPGPSSLRSSMRSRSLSPLIGSETQPLHPGGQWPAQAELTDESTVPLEPQQRKGAESYVGVRYITEALIKKLTKQDNLALVKSLNLSLSKDGGKKFRYIENLEKCVKLEVLNLSYNLIVKIEKVDKLLRLRELNLSYNKISKIEGLENMCNLQKLNLAGNEIEHIPVWFAKKLKSLRVLNLKGNKISSLQDVSKLKPLQDLTSLVLIDNPVVALPHYLQFIIFHLRSLESLEGQPVTTQDRQEAFERFSLEEIERLEKDLEKKTVETEELKNKQTKFLEEIKNQDKLNKSLKEEAMLQKQSCEELESDLSTKKEL-------------LKQKTVELTRACQKQYELEQELAFYKIDAKFEPLNYYPSEYAEIDKYPDESPYIGKSRYKRNMFATETYIVSDAQAVQIRKMVPEGGQLRHEHTPPRVQAPPDLQLEDTEKKISAAQTRLSELHHEIETAEQKVLRATQEFKQLEEAIQQKKISEAEKDLLLKQLSGRLQHLNRLRQEALDLEIQMEKQRKEIAEKHEEINTVQLATDSLDPKDPKHSHMKAQKRGKEQQLDIMNRQYTQLESRLDEILCRIAKETEEIKDLEQQLTDGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLQDEKETLLQRLTEVQQEKEELELIAMDAENMRKELAELESALQEQHEVNASLQQAQGDLSAYETELETQLKLKDAETSQLKQELEKLLRRTQLEQSVLQTELEKERESLRDALGKAQSSEEKQQENNELRTQLKQLQDDNSLLKKQLKEFQNHLNHVVDGLIHPEEVAARVDELRKRLKLGAGEMRIHSPSDVLGKSLADLQKQFSEILARSQWEKEEAQVRERKLHEEMALQQEKLANGQEEFR-QACERALEARIKFDKRQHNARIQQLENEIHYLQENLKSMEKIQGLTDLQLQEADEEKERILAQLQELEKKKKREDARSQEQFLGLDEELKSLKKAVAASDKLAAAELTIAKDQLKSLHGTVVRINQERAEELQEAERFSREAMQAAKDLSRAEAEIELLQHLLREREGQFRDEMENADLGAKGANSQLLEIEALNEAMAKQRAEITRLRDVLNLTGAGTKGGIENVLEEIAELRHAVSAQNEYISSMADPFRRQGWWYFMPPAPSSKVSSHSSQATKDSGLGLKYTASTPLRKPQPGQQEEKDSSGPLPASGYWVYSPIRSTLHKSFSKREDADSGGDSQEESGLDDQEEPPFVPPPGYIMYTVLPDGSPVPQGVALYAPSPPLPNSSHPLTPGTVVYGPPPAGAPIIYGPPPANFAVPLVPAGVQHCNIPEHHNLENEVSRLEDIMQHLKSKQREERRQKASTQHSEEEVDGLHRDIDDLLQEKKELELEVEELHRTIERHQQRKDFIDGHVENLMTELEIEKSLKHHEDIVDEIECLEKTLLKRRSELREADRLLAEAENELACTKEKTKSAVEKFTDAKRNLLQTESDAEALEKRAQETALNLVKAEQQLRLLQADAEDLEQHKIKQEEILKEINKVVAAKDADFQCLNEKKEKLTEELQSLQRDIKAAQHSEDHHLQVLRESETLLQAKRAELETLKSQVTSQQQELAVLDSELGHRREELLLLQDSLAQAKADLQEALTLGETEVAEKCSHIREVKSLLEELSFQKGELNVHISEKKTQLALIQQEMEKEEKNLQVVLQQLSRHKTELKNVADILQLETSELQGLKLQHDQKVVELEKAQVDVLEEKLELENLQQATQQQRRELERQRQLLERDRRETERVRAESQALQSCVECLSKEKEDLQGQCESWEKKSSHAQRVLAATEESNKMEQSNLGKLELSVRKLRQELEQLSQDKLALHSEVAEVQQQLQGKQEAINSLQEELDSTQDHLDLAKQDLIHTTKCQNELLNEQTQLQEDISKWMARLESCQKETETKEQQVQQLQDEIRESKLRLDQQEMMFQKLQKEREREEQKFEAGKVTLEQQQRQLEKELTDQKSRLKQLLTDVSAAEGRLGTLQEEERRIEGLERMLSQAKQQLSEREQQLMAKSGELLALQKEADDMRADFSLLRNQFLTERKKAEKQVAGLKEALKIQRSQLEKNLLEQKQENSCMQKEMATIELVAQDNHERARRLMKELSQMQQEYLELKKQVANQKDLERRQMEVSDAMRTLKSEVKDEIRTSLRNLNQFLPELPADLASILERNENLR-ELESLKENFPFTTKERIFEEKSNFPQVHIMDEHWRGEALRQRLRRHEDQLKAQLRHCMSKQAEVLIKGKQQTEGTLHSLRRQVDALGELVTSTSTDSASSPSLP----SLVEDSQHGHSQSSFQVLQVPLEEPNSYRH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z7A1-1", "uniprot_id": "CNTRL_HUMAN", "id": "Q7Z7A1-1", "name": "Centriolin", "aln": "MKKGSQQKIFSKAKIPSSSHSPIPSSMSN-MRSRSLSPLIGSETLPFHSGGQWCEQVEIADENNMLLDYQDHKGADSHAGVRYITEALIKKLTKQDNLALIKSLNLSLSKDGGKKFKYIENLEKCVKLEVLNLSYNLIGKIEKLDKLLKLRELNLSYNKISKIEGIENMCNLQKLNLAGNEIEHIPVWLGKKLKSLRVLNLKGNKISSLQDISKLKPLQDLISLILVENPVVTLPHYLQFTIFHLRSLESLEGQPVTTQDRQEAFERFSLEEVERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKSDLNTKNEL-------------LKQKTIELTRACQKQYELEQELAFYKIDAKFEPLNYYPSEYAEIDKAPDESPYIGKSRYKRNMFATESYIIDSAQAVQIKKMEPDE-QLRNDHMNLRGHTPLDTQLEDKEKKISAAQTRLSELHDEIEKAEQQILRATEEFKQLEEAIQLKKISEAGKDLLYKQLSGRLQLVNKLRQEALDLELQMEKQKQEIAGKQKEIKDLQIAIDSLDSKDPKHSHMKAQKSGKEQQLDIMNKQYQQLESRLDEILSRIAKETEEIKDLEEQLTEGQIAANEALKKDLEGVISGLQEYLGTIKGQATQAQNECRKLRDEKETLLQRLTEVEQERDQLEIVAMDAENMRKELAELESALQEQHEVNASLQQTQGDLSAYEAELEARLNLRDAEANQLKEELEKVTRLTQLEQSALQAELEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQDDNNLLKQQLKDFQNHLNHVVDGLVRPEEVAARVDELRRKLKLGTGEMNIHSPSDVLGKSLADLQKQFSEILARSKWERDEAQVRERKLQEEMALQQEKLATGQEEFR-QACERALEARMNFDKRQHEARIQQMENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKKKLEDAKSQEQVFGLDKELKKLKKAVATSDKLATAELTIAKDQLKSLHGTVMKINQERAEELQEAERFSRKAAQAARDLTRAEAEIELLQNLLRQKGEQFRLEMEKTGVG-TGANSQVLEIEKLNETMERQRTEIARLQNVLDLTGSDNKGGFENVLEEIAELRREVSYQNDYISSMADPFKRRGYWYFMPPPPSSKVSSHSSQATKDSGVGLKYSASTPVRKPRPGQQDGKEGSQPPPASGYWVYSPIRSGLHKLFPSR-DADSGGDSQEESELDDQEEPPFVPPPGYMMYTVLPDGSPVPQGMALYAPPPPLPNNSRPLTPGTVVYGPPPAGAPMVYGPPPPNFSIPFIPMGVLHCNVPEHHNLENEVSRLEDIMQHLKSKKREERWMRASKRQSEKEMEELHHNIDDLLQEKKSLECEVEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSELREADRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTEELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQGSMVQAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEKCDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRADFSLLRNQFLTERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMKELNQMQYEYTELKKQMANQKDLERRQMEISDAMRTLKSEVKDEIRTSLKNLNQFLPELPADLEAILERNENLEGELESLKENLPFTMNEGPFEEKLNFSQVHIMDEHWRGEALREKLRHREDRLKAQLRHCMSKQAEVLIKGKRQTEGTLHSLRRQVDALGELVTSTSADSASSPSLSQLESSLTEDSQLGQNQEKNASAR-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3ASW8-1", "uniprot_id": "A0A8M3ASW8_DANRE", "id": "A0A8M3ASW8-1", "name": "", "aln": "MKRGFQMRKQSPILGTKISKSP---------QSKPVTPNTTSLPEAEDGG----PREEPSDED-----------KRQYKGTRYITEDLIRRVTKCENVVLVRTLDLSMAMGSNHQFRYIENLDKCDRLQVLNLSNNRIERIEKLEKLCQLRELHLSRNRIHKIEGLEHMTKLQVLNLAFNNIEDLPVWFGKKLRSLQTVNLQSNNISSLHELAKLKPLNNLTCLTLAGNPVSSLAHYHLFLIFKLRSLEILDGQQISPQEREQAHQRFHMEEVERLEQELELRAEEIDRLQRERTIALEQLEQQETVNQNLRQQNQDQQHSHEELKRELDTKSELPPHHTPLLDSLCQLKQKTVELTQACQKHYELEQELAFHKIDVKFEPLPFYPDPEVEVDNLISESPYIGKSRQKRNIKFPS---ETENTGTQGQQKHPPASDLTETDSPGDYMS---------RHAQLAAEMKLQQLHKEIEAREQQILTASEELRQLEDAVSQRRISEAEKEQLRQELQRRIQNLGELRGEMEAVEKQLDRLNAERNQAQDEMEQLQNLLHSLDPSDPKHTHVKAQLSRKSQLLAIMSRKHQELERRLDDMITRIHKETEEIKDLEQQLTDGQIAANEALKRDLEGIISGLQEYLRGVKDQARRAQSDCRRLQREKDTLQHLLDMKEQEFTQLENKALSAEITQKELELQKQEFDNLMKENEELKRARGQVSEYEAELESQLQQRDTEATQLKEELDRLRRLTQMEHSALQAELQKERQAKENALAQVRMAADKELENTQLLQQINALQEERDCLKEEVEAFQDDLNSVREQLLCPESVARHLGELRRGITTGQKELSFEDLGEPVNKKFMELQQEVHRVVSAAQRDRDEAQRCQDRLTGEMSSLRERLRKYQERHQTQTTERRGE-----------------EAELHRLREELEEAREQHYLMAQRLEETEIDRDRILGELEEQDKQMNAEKTQTQEQLESLNLEMQALRRSFSSADRQAAQQLITAKDKLHSLHSTVEKINLERAANAEELQSTRIQAAQAIQDLTNAEAEIQVLQKLLSDR----VQETDGNLHGLQNSQIQQEELDRLNQALKRQQAQTKRLRDQLAQAKGANNINLDELLEEIGALKETLLQQNNFLSSLGDPSPNTGYWYYVPS--NQHAPSLGSQGTQDSGLGSVHPHS-PERNRRSGNRACRE-RRPPANGGYWVYSPNPYSHGK-----RDAQVSRDSGRESDMEGTRFTPLSAPAGFTLH----DSTAFPPGSFIYSHSVPG----LPIGASTVLYGPPPDPARLVYGPPPANLTVPLVPSGTLHCNVPGHQDLE----------RDLKKAERRLREECADRAHSEQEQHTLQDKTAELQQEIKHLRRTVRTLQRHTSG-----------LESTLSHAEEEQ------CVLGEVECLEKTLLKRRAELREADRRLLEADAQLKNTQTKTEENIHHYNEAKKRMEETERELAEIEKRAQDSGKLLVQSKQQLRSLQEEVMTLQKRKEDKERSLHDAEEVLTCHDSKFQDVSRKLERANDRLEIAEKELRETQSMEVKLLQSCREMENSLAQRKTKLDEVNTQVMLQQKELSLLDRKLEQWKREEEVLRVSVEQHRQALLDVLRQGEEDAKLLQQRVQELRVDVHSLAVQKGELDSQLSERKTRLAQLKKDQQQEEETLQSLRSVIKKHKAELARMLEMIQLETGELEDVKLQCNQKLEQLEKSQETLLQVRVELQCVQQELQEQREEAERQ---MEKDRVELHSLQQKSLHLQQQTEAAVQERSSLQEQCRNLEARRTHAQRCLEAAETRTSEAETELLRVQAELNKLQQELKQTQDLHLEISRDNVAVQK---RHEEELSKLKKQLVDSQTLVDEVREEGKSARKQWEELVKKQKELKAELKEREEKIRRRQQKMERMEEQLQELKAEISVKQTQLEDHEKLMRVQQQQSTDLEQQLRLK----EQKLQAVERALVLKLERMEQLTVADLDLQG-------EYKHCTALQQQVDQLEQELCERDARLQQAFKDTHRLQETLLSEKTNHSHTN------------------------RSNLQR----VEKDRVRLQSDLLTIEKSAQENHQQARTLQKQLGTISQELLSLKDTVQT---LQKQEEESSSAFWEIN-----------------------RSTAELETPSSASSDTDSLKENRPAVTLS------MGNPAYNTEDEQWRGEALRERLRQQEDHLKVQLRRRMFSQQEALSQRRLQTEGSIQGLRRRVDKLDQLLGSSSKDCSYLSDQE-----LLPKHTNGRDRKKWSADPFELK-------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:* : : * . *: * :*:.::* * . . . * : * :**. : *.***** **:::** :*:.*:::*:**:: ...::*:*****:** :*:***** * * :***::** :****:** *:* ****:*:* :** **** *:**.:* *:.***:**:.:**:.*:****::::*****::* .* * *** :*.** * **:***** *:** ::.*:*::*.:** :**:****::** : * :.*: ::* **::::*:.:*:.*::: *::* ***: :*.**.** *****:***:****:*********:***.***** :**. .*:*: .********* ***: .. . ..* :: * :* . . : : **: :*.:**.*** **::* *::*::***:*: ::**** *: * ::*. *:: :..** * :* *::: . * :.*:: * . **..***::*:*** *.* * **.::: :** ***::: ** .*********:***:**********:****:******** :*.** :**.:**:*: **:** : * :** :** *:.** :*** :. ::: : * .*::::*::* **:***::*: :*:*:.***:**:.: * **:*:*.**:**:***:: .:**.:.: : :*: **.:* ::: **::.. **:::: **..** * : *: **.** ::.***: :. * *: :.. .: :.*.: :**::. .::: :: :::*** : :* **: :*:* . **..: *: ** * * *:* *:*:*:. .: : * :*:*:: :::***.:*.* :*: . *.:::***. .*: *:: *:::.:::*: *: :* **::*:***.** :** *** : :* : :* ** :**:.*****::**:** :: * : * .:: * *:: *:::: :*::: **:: * : .: .:::::***. *:. : **:::**:.** . * **::*. ..:..* .**.*:***:* . * * *. :.*:: : * . .******* * **: . ** .** ::. . .*: .*.*: :: *.:..* * :*: . * *: ..**:***** * ::*****.*:::*::. *. ***:* *::** :.**. .:. * :. :.*:* . *: . :* ** * *. *. *:* . :*. ::. * *: ::.*:**:********:******* * **: :* *: **:. :.::.:**: : :** : :*:***::. **::.**** ** :. *:::* .:*. *:: :::::.:*:.** :..* *: .:.*: ::::. :: * : ** :* * * ::::*: :::** **:*:::** :* : :.* :*: *: * : * :.* ** :. .:::*:: :..*:.*****: ::**::*:*: :::: ::**:.*: : :.:**:** .: :::***. **:.:*** :*:: :***:* :*: ::**: :** *:*: * * * :*:*: * . : :: **. *. :*:. ** :* * : ::::* * *:* .. :::* ::: .:.**:***. . :* : : *: :.* :..*:::* . * :: .::: : * . *:.:* .*: ::.: ::. *:: * ::*:* *: ** .: :* ::* ::: *:: *.:: ::: :*: * : .::. : : * : .*:: :.* :::*.**: :* : **: . :::.* . **:*:: :::. :*.:: *** **:**::** * *:* :. * .**. : . ::::: * *.*: :: : ** .. : :*:*** * . . . . : **: ******::**::**:**.*** * .* *.* : : ****:::.***:** *.:*: *:* *.: .. * . *:.:.. ", "identical_positions": 759, "similar_positions": 803, "identity": "32.24%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120612-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43739-1", "uniprot_id": "CYH3_HUMAN", "id": "O43739-1", "name": "Cytohesin-3", "aln": "MDEDGGGEGGGVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFIAMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGGGRVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O08967-1", "uniprot_id": "CYH3_MOUSE", "id": "O08967-1", "name": "Cytohesin-3", "aln": "MDEGGGGEGGSVPEDLSLEEREELLDIRRRKKELIDDIERLKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQFLYKGEGLNKTVIGDYLGERDDFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAFASRYCLCNPGVFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAERFITMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGG-RVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEDPRKPNCFELYNPSHKGQVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKASISRDPFYDMLATRKRRIANKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F2Q0-1", "uniprot_id": "E7F2Q0_DANRE", "id": "E7F2Q0-1", "name": "", "aln": "MNMD---EDNRVPEDLSFEERDELSNIRRRKRELLDDIERLKLEISEVMTEIEHLTCVRETKSTQRSKQIAVGRKKFNMDPKKGIQFLLENDLLQHTPEDIAQFLYKGEGLNKTVIGDYLGERDDFNIRVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRMMEAYAARYCQCNPGVFQSTDTCYVLSFSVIMLNTSLHNPNVRDKPSVERFISMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDREGWLLKLGG-RVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIPLENLSIREVEEPRKPNCFELYNPSHKGQVIKACKTEADGKVVEGNHVVYRISAPTPEEKEEWIKSIKASISRDPFYDMLATRKRRVATKK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . *.. ******:***:** :*****:**:******* **:******::**.*.*:*:***.****:****************:****** :***:***********************:***:******************************************:*:*** *****************::********* ******:.****:******************************************************** *******************************************:****************************:**************:*******:**********************:*.**", "identical_positions": 353, "similar_positions": 36, "identity": "88.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120612-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5SUE8-1", "uniprot_id": "ANR40_MOUSE", "id": "Q5SUE8-1", "name": "Ankyrin repeat domain-containing protein 40", "aln": "MSALLEQKEQQERLREAAALGDIREVQKLVESGVDVNSQNEVNGWTCLHWACKRNHGQVVSYLLQSGADREILTTKGEMPVQLTSRREIRKIMGVEEADEEEE----IPQLKKESELPFVPNYLANPAFPFIYTPAAEDSTQLQNGGPSP---PPVSPPADSSPP---LLPP---TETPLLGAFPRDHSSLALV----QNGDISAPSA-----ILRTPESTKP--------------GPVCQPPVSQNRSLFS-VPSKPPVSLEPQN--GTYAGPAPAFQPFFFTGAFPFNMQELVLKVRIQNPSLRENDFIEIELDRQELTYQELLRVSCCELGVNPDQVEKIRKLPNTLLRKDKDVARLQDFQELELVLMISDNNFLFRNAASTLTERPCYNRRASKLTY", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6AI12-1", "uniprot_id": "ANR40_HUMAN", "id": "Q6AI12-1", "name": "Ankyrin repeat domain-containing protein 40", "aln": "MNALLEQKEQQERLREAAALGDIREVQKLVESGVDVNSQNEVNGWTCLHWACKRNHGQVVSYLLKSGADKEILTTKGEMPVQLTSRREIRKIMGVEEEDDDDDDDDNLPQLKKESELPFVPNYLANPAFPFIYTPTAEDSAQMQNGGPST---PPASPPADGSPP---LLPP---GEPPLLGTFPRDHTSLALV----QNGDVSAPSA-----ILRTPESTKP--------------GPVCQPPVSQSRSLFSSVPSKPPMSLEPQN--GTYAGPAPAFQPFFFTGAFPFNMQELVLKVRIQNPSLRENDFIEIELDRQELTYQELLRVCCCELGVNPDQVEKIRKLPNTLLRKDKDVARLQDFQELELVLMISENNFLFRNAASTLTERPCYNRRASKLTY", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FE71-1", "uniprot_id": "E7FE71_DANRE", "id": "E7FE71-1", "name": "", "aln": "MSTTSLDKELQERLREASAIGDIDEVKTLVESGVNVNSQNEINGWTCLHWACKRNHKQIVAYLLNNGADKDILTAKEELAVQLTSKPEIRRLLGVEEEDEPEV---------KEPELPIIPNYLSNPPFLYSKMNKDNLSIAQQNGTNSTHAEPLESEPATLSPTQEQQLPAPSHQQPKSLYTDSQSQQELTFVPGVEQNGVVPSPVVNGGLPMELSSETHHTNHCEFTHAHPIAQNGPVCPSASTSQPPQLPGTTISRQQSIQPQINCSQISGSMPAFQPFFFTSTFPVNVQELVLKVRIQNTNIRENDFIEVELDRQELTYRALLRVCCRELDISAEHVEKIRKLPNTMLRKDKDVARLQDFQELEVVLEKTEGLSLFS-AQGGLTDRPCYNMKASRLTY", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.: :** *******:*:*** **:.******:******:************** *:*:***:.***::***:* *:.*****: ***:::**** *: : **.***::****:**.* : : * *** *. * * ** **. **. :. * : .:.: .*::* *** :.:* . : :.*: :. **** .. :.. . :. .. . *::** . :*. *********.:**.*:***********..:*******:*********: ****.* **.:..::**********:*****************:** ::. ** * . **:***** :**:***", "identical_positions": 199, "similar_positions": 95, "identity": "49.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120613-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K285-1", "uniprot_id": "FCHO1_MOUSE", "id": "Q8K285-1", "name": "F-BAR domain only protein 1", "aln": "----MSYFGEHFWGDKN--HGFEVLYHCVKQGPVATKELADFIRERANIEETYSKAMAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLHDLLKDVLRYGEEQLKTHKKCKEEVLGTVDAVQMLSGVGQLLPKSRENYLSRCMD----LERLRRENTSQKEMDKAETKSKKAADSLRRSVDKYNSARAD-FEIKMLDSALRFQAMEEAHLQHMKALLGSYAHSVEDTHVQ-IGQVHEEFKQNVENVTVDMLLRKFAESKGTGREKP-GPLDFDAYSSAALQE--------AMKRLRGAKAFRLPGLSRRE----PRASVDFLESDSGVPPEVDDEGFTVRPDISQNNGAEPPRFSSSDSDFDDEEPRKFYVHIKPAPTRAVACSSEAAAAQLRATAGSLILPPGPGGTMKRHSSRDTSGKPQ--RPRSAPRTGSCAEKPLASEEPLSKSLFGPPLESAFDHDDFTGSSSLG--FTSSP--SPFSSSSPENVEDSGLDSPSHAAPGPSPE--SWVPRPGTP-QSPPTCRAQHPEPR---------GLMPRAPSPGPWGPEG--GADSL-TPADPT-REGLAATLRRPRSRKVSCPLTRSNGDLCRSLSPSPLGSSAPTIPPDRPSFSTQMGHGISRGPSPVVLGSQDALPVATAFTEYVHAYFRG-HSPSCLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVNTAPVEHFQPNADLIFSDPSQSDPETKDFWLNMAALTEALQHQAEQNPTASYYNLVLLRYQFSRPGPESVPLQMSAHWQCGPTLTRVSVEYSYRAGATAVSTPLTNVQILLPVGEPVTSVRLQPAATWNTEEKRFTWKLPDVCEAGGSGHLSASWQPQSGPSTPSP-VAAQFTSEGATLSGLDLEL---LGGGYRMSLVKRRFATGMYLVSC--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZIM5-1", "uniprot_id": "D3ZIM5_RAT", "id": "D3ZIM5-1", "name": "", "aln": "----MSYFGEHFWGDKN--HGFEVLYHCVKQGPVATKELADFIRERASIEETYSKAMAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLHDLLKDVLRYGEEQLKTHKKCKEEVQGTVDAVQMLAGVGQLLPKSRENYLSRCMD----LERLRRENTSQKEMDKAETKSKKAADSLRRSVDKYNSARAD-FEIKMLDSALRFQAMEEAHLQHMKTLLGSYAHSVEDTHVQ-IGQVHEEFKQNVENVTVDMLLRKFAESKGTGREKP-GPLDFDAYSSAALQEGNYPLLSTAMKRLRGAKAFRLPGLSRRE----PRASVDFPESGSGVPPEVDEEGFTVRPDTSQNSEAEPPRFSSSDSDFDDEEPRKFYVRIKPAPARTMACSSEAAAAQLRATAGSLILPPGPGGTMKRLSSRDTSGKPQ--RPRSAPRS-SCTEKPLASEEPLSKSLFGPPLESAFDHEDFTGSSSLG--FTSSP--SPFSSSSPENVEDSGLDSPSLAAPGPSPE--SWVPRPGTP-QSPPTCRAQHQEAR---------DPVPRVPSPGPWGPEAGAGADSL-TLADPT-REGLAATLRRPRSRKVSCPLTRSSGDLCRSLSPSPLGSSAPTIPPDRPSFSAQMGHGVSRGPSPVVLGSQDTLPVATAFTEYVYAFFRG-HNPSCLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTSPIEHLQPNADLIFSDPSQSDPETKDFWLNMAALTEALQHQAEQNPTASYYNLVLLRYQFSRPGPKSMPLQMSAHWQCGPTLTRVSVEYSYRAGATAVSTPLTNVQILLPVGEPVTSVRLQPAATWNTEEKRFTWKLPDVREAGGSGHLSASWQPQSGPSTPSP-VTAQFTSEGATLSGLDLEL---LGGGYRMSLVKRRFT-GMYLTSC--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O14526-1", "uniprot_id": "FCHO1_HUMAN", "id": "O14526-1", "name": "F-BAR domain only protein 1", "aln": "----MSYFGEHFWGEKN--HGFEVLYHSVKQGPISTKELADFIRERATIEETYSKAMAKLSKLASNGTPMGTFAPLWEVFRVSSDKLALCHLELTRKLQDLIKDVLRYGEEQLKTHKKCKEEVVSTLDAVQVLSGVSQLLPKSRENYLNRCMD----QERLRRESTSQKEMDKAETKTKKAAESLRRSVEKYNSARAD-FEQKMLDSALRFQAMEETHLRHMKALLGSYAHSVEDTHVQ-IGQVHEEFKQNIENVSVEMLLRKFAESKGTGREKP-GPLDFEAYSAAALQE--------AMKRLRGAKAFRLPGLSRREREPEPPAAVDFLEPDSGTCPEVDEEGFTVRPDVTQNSTAEPSRFSSSDSDFDDEEPRKFYVHIKPAPARAPACSPEAAAAQLRATAGSLILPPGPGGTMKRHSSRDAAGKPQ--RPRSAPRTSSCAER-LQSEEQVSKNLFGPPLESAFDHEDFTGSSSLG--FTSSP--SPFSSSSPENVEDSGLDSPSHAAPGPSPD--SWVPRPGTP-QSPPSCRAPPPEARGIRAPPLPDSPQPLASSPGPWGLEALAGGDLMPAPADPTAREGLAAPPRRLRSRKVSCPLTRSNGDLSRSLSPSPLGSSAASTALERPSFLSQTGHGVSRGPSPVVLGSQDALPIATAFTEYVHAYFRG-HSPSCLARVTGELTMTFPAGIVRVFSGTPPPPVLSFRLVHTTAIEHFQPNADLLFSDPSQSDPETKDFWLNMAALTEALQRQAEQNPTASYYNVVLLRYQFSRPGPQSVPLQLSAHWQCGATLTQVSVEYGYRPGATAVPTPLTNVQILLPVGEPVTNVRLQPAATWNLEEKRLTWRLPDVSEAGGSGRLSASWEPLSGPSTPSP-VAAQFTSEGTTLSGVDLEL---VGSGYRMSLVKRRFATGMYLVSC--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FBF7-1", "uniprot_id": "FCHO1_DANRE", "id": "E7FBF7-1", "name": "F-BAR domain only protein 1", "aln": "----MIHFFHTLQGEKN--AGFDVLYHNMKHGQIATKELAEFVRERAAIEETYSKSMSKLAKMASNGSPLGTFAPMWDVFRVSSDKLALCHLELMRKMNDLIRDINKYSDEQVKIHRKTKEEAIGTLESVQSLQVQNGHLQKTREGYHSKCVE----LERLRKEGVPQKELEKAELKCKKAAESFAGSIEKFNRAGGD-FEQKMSESAQKFQDIEEAHLRQMKLLIKGYSHSIEDTHVQ-VGQVHEEFKQNVENIGIENLIQKFTEQKGTGKERPEGPVGFEEYLSSLASE--------NSKKSR-AKAFRIPGLGKRDKEPDSTVHVYFLQNNS--PLEVDDEGFVIRADVKQNDIEKEGNFYSSDSDFDDEEPKKFHIQIRPVAS-SNRSNSAANEQELKATVGALTLPPNRVVSVKKQLSRRSEGEGESVPQRVIAKVEVCACR-LSSTASGSDALFGPPLESAFKSHSFSGREQLQNAFAASEFFSKFYSSSLENVEDSGLDSPSHQPLGVSPDPTGWAAWPSSQSQSKDSINAASQSRGGSNRPTPSPNPAPSSQSNTEWMNDIIREGPYSQIMQDSSERLALAPP-RSVRSKRSSVAITRKNSDFSRSLCSSPLPDPNASTCVLYSKMLNCAPAGLSRGPSPISLSAQESWPVAAAITEYINAYFRGGEHNRCLVKITGDLTMSFPAGITRIFTANPNAPVLSFRLVNISRVDHFLPNQKLLYSDPSQSDPDTKDFWFNMQALTLHLQREAELNPQASYYNVALLKYQASSQDPSRAPLLLSAECQRSGTVTRVSLDYHCCP-ATAPATQLTSVQVLLPLDHSATDLQCQPPAAWNAEERRLLWKLDDLSSVSGSGTLCASWQCLEVPRGPAPSLAVQFVGSGASLSGLDVEL---VGSRYRMSLVKKRFATGKYMAGCSL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P25623-1", "uniprot_id": "SYP1_YEAST", "id": "P25623-1", "name": "Suppressor of yeast profilin deletion", "aln": "MTEQRTKYADSILTTKSPYEATETIRIRLSQVKLLNKDFYLLFKELANLKRNYAQQLRKIIAENEDITKILN-AQMIESNVLTPQEMSAFRFNSLGELRNVWDTVIEELKSDLKSSTEYYNTLDQQVVRELKESVENNTSWRESKDLHSKLSKNAASIEHYSKNNENSSHLEEARRQWDQQSPYLFELFETIDYNRLDTLKNCMLRFQTSFSDYLLNTTKECETVMTKFLAFEPQSEIDRFAKDASQYNFQLSSSSKEVVPNNASPASATG-ARPVSVSNGAANTEREKK---------SPQKDKRKSAFGNIGHRLAS---ASSSLTHNDLMNNEFSDSTNNSSLKSKKSSHTLRSKVGSIFGRNKTKNKRQQQSSSNSHIQASITETPNNSSTRVSSTATSSIYQKQRRPTYSSSKSNNWTPGEASDTPPLPPHATPKN---VDAPVTADTPPAQTFTPSEVPPSTPQQSSPPTAKEP---DSSN----LPKTVPISISQPPLQPQSKTKPLPVEPASPSISLPTATVDNQPSGQVDSRPLH-----------IRAPALPPSRKQNFIHNRDSQLYDSLPNHGSGATPTSSSLSSIPQERPVSTLSSQITGELRELNPQATGSSTSLVGQSLFQHSSLDTS------------QFGLNASIAEVLNASFKD--GMLQNSQLIGEIALNYLP---NSVMNSPLPIGINLRINNGAKFEKVILNQAFIERVAPEEFKVNPSFIDSRTLGAIKYSIKEPIAPIVIHPVWRFESHQASVVLTVKMSPSLPDEIS---QIVIEDLVVFVNIDGANATSALSKPQGSFSKEKKRITWRFKEPVVLTRNGEGQRLIARFITDGLAHESAKGVITKFTISETDNVALPHSGAGSGITLTCQELDENNPFGGEWLDVNTKRTLTTGNYHGLA--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . : *. . :.: :.: : .*:: :.:* * ::..*:: : *: .: : : . * : : ::.:::: ::: ::.:: : . ..::* : : : . : :. .: . *: ::. ...:::*. : .: : : .:. : * :: * *. :. : :: : ::.:: ..: .::: ::.. : : .: : ..** :* . . . :: : .** * . . . .. ..::..: : . * ..:. . :: . :*:. : : .. :: * : .. : .. : .: . : : :. : . : .: .. . . :* : .: .:.:. *:. * . * : :. : .. : .. . :.. * . .:: ..:: .* . .: .: . * : ::::* : * *:. :: *::::.: . . . .* . :.:*: : : .::. * :: ..:. . .* . : . : * . : : :* * . . :. . . :. .: .: .: *:. * :. . : : ... . : . : . . . . :. . ...* :*: ::: .*. : .*: :: * * . ", "identical_positions": 48, "similar_positions": 316, "identity": "5.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120628-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88778-1", "uniprot_id": "BSN_RAT", "id": "O88778-1", "name": "Protein bassoon", "aln": "MGNEASLEGGAGEGPLPPGGSGLGPGPG----AGKPPSALAGGGQLPVAGAAR-AAGPPTPGLGLVPGPGPGPGPGSVSRRLDPKEPLGSQRATSPTPKQASATAPGRESPRETRAQGLSGQEAEGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTSS-QPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALS--PAHSPAKQPLGKPEQERS---RSPGATQSGPRQAEAARATSVPGPTQATAPPEVGRVSPQ--PPLSTKPSTAEPRPPAGEAQGKSATTVPSGLGAAEQT--QGGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPSPSKGPPKIVFSDASKEAGPRPPGSGPGPGPTPGAKTEPGPRTGPGSGPGALAKTGGTPSPKHGRADHQAASKAAAKPKTMPKERA-ACPLCQAELNVGS-RGPANYNTCTACKLRVCTLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPAPLPLPTPQEPPAGVPQRAAGASPLKQKGPQGPGQPSGSLPPKASPQAAKASPQAAKAS--------------PQAKPLRASEPSKTSSSAPEKKTGIPVKAEPVPKPPPETAVPPGTPKAKSGVKRTDPATPVVKPVPEAPKSGEAEEPVPKPYSQDLSRSPQSLSDTGYSSDGVSSSQSEITGVVQQEVEQLDSAGVTGPR-PPSPSELHKVGSSMRPSLEAQAVAPSGEWSKPP--SGSAVEDQKRRPHSLSIMP-EAFDSDEELGDILEED-DSLAMGRQREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPAR-ADMTDEEFMRRQILEMSAEEDNLEEDDTAVSGRGLAKHGAQKASARPRPESSQESVALPKRRLPHNATTGYEELLSEE-GPAEPTD--GALQGGLRRFKTIGLNSTGRLWSTSLDLGQGSDPNLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAETLDGGPTRLYKSGSEYNLPAFMSLCSPTETPSGSSTTPSSGRPLKSAEEAYEDMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRSQGSFEYQDTLDHDYGGRASQPAADGTPAGLGATVYEEILQTSQSIARMRQASSRDLAFTEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFPTSTSSDSSGGRVIPDVRVTQHFAKEPQEPLKLHSSPASPSLASKEVGMTFSQGPGTPATTAMAPCPASLPRGYMTP---AGPERSPSTSSTIHSYGQPPTTANYGSQTEELPHAPSGPAGSGRASREKPLSGGDGEVGPPQPSRGYSYFTGSSPPLSPSTPSESPTFSPSKLGPRATAEFSTQTPSLTPSSDIPRSVGT--PSPMVAQGTQTPHRPSTPRLVWQQSSQEAPVMVITLASDASSQTRMVHASASTSPLCSPT-DSQPASHSYSQTTPPSASQMPSEPAGPPGFPRAPSAGVDGPLALYG----------WGALPAENISLCRISSVPGTSR-VEPGPRPPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPVPGRQSTAVQPLVINLNAQEQTHTFLATATTVSITMASSVLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLAQVK----------------------------QVEQAVQTAPYRGGPRGRPREAKFARYNLPNQVTP-LARRDILITQMG-----TAQSVSLKPGPVPEP------------GAEPHRATPAELRAHALPG---TRKPHTVVVQMGEGAAG--TVTTLLPEE----PAGALDLTG-MRPESRLACCDMAYKFPFGSSCTGTFHPAPSAPDKSVTDAALPGQSSGPFYSPRDPEPPEPLTFRAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRDSAVDLSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLSHPLPMRPYSSVSNIYSDHRYGPRGDAVGFQEASLAQYSATTAREISRMCAALNSMDQYGGRHGGGSGGPDLVPYQPQHG-PG--LNAPQGLASLRSGLLGNPTYPEGQPSPGNLAQYGPAASQGTAVRQLLPSTATVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYGSGGVTAVPLTSLTRVPMIAPRVPLGPAGLYRYPAPSRFPIAS------TIPP----AEGPVYLGKPAAAKASGAGGPPRPELPAG----GAREEPLSTTAPPAVIKEAPVAQAP----APPPGQKP--AGDAAAGSGSGVLGRP--------------------------------VMEKEEASQEDRQRKQQEQLLQLERERVELEKLRQLRLQEELERERVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQLQQQLQQQLEEQKQRQKAPFPATCEAPSRGPPPAATELAQNGQYWP------------PLTHTAFIAVAG----TEGP---------GQAREPVLHRG-LPSSASDMSLQTEEQWEAGRSGIKKRHSMPRLRDACEPESGPDPSTVRRIADSSVQTDDEEGEGRYLLTRRRRTRRSADCSVQTDDEDNAEWE-QPVRRRRSRLSRHSDSGSDSKHEASASSS-AAAAAARAMSSVGIQTISDCSVQTEPEQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQAQGVAGPQLIGPTAISPYLPGIQIVTPGALGRFEKKKPDPLEIGYQAHLPPESLSQLVSRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQ-KQFIADSTLRQQTLPRPMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPP-NGLVRKVKRTLPSPPPEEAHLPLAGQVPSQLYAASLLQRGLAGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLAKDRVGRDYPPLRGLGEHRDYLSDSELNQLRLQGCTT---PAGQYVDYPASAAVPATPSGPTAFQQP--------RFPPAATQYTAGSSGPTQNGFLAHQAPTYTGPSTYPAPTYPPGTSYPAEPG-------------------LPSQPAFHP-TGHYAAPTPMPTTQSAPFPVQADSHAAHQKPRQTSLADLEQKVPTNYEVISSPAVTVSSTPSETGYSGPAVSSSYEHGKAPEHPRGGDRSSVSQSPAPTYPSDSHYTS-LEQNVPRNYVMIDDISELTKDSTPTASDSQRPEPLGPGGVSGRPGKDPGEPAVLEGPTLPCCYGRGEEESEEDSYDPRGKSGHHRSMESNGRPASTHYYSDSDYRHGARADKYGPGPMG-PKHPSKNLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYPPPTVSSSLTSRSRKFQDEITYGLKKNVYEQQRYYGVSSRDTAEEDDRMYGGSSRSRVASAYSGEKLSSHDFSSR-SKGYERERETAQRLQKAGPKPSSLSMAHGR-ARPPMRSQASEEESPVSPLGRPRPAGGALPPG-DTCPQFCSSHSMPDVQEH-VKDGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHTVSSS-QKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHTSAKEHRHHGDHGRHSGRHAGE---EPGRRAARPHARDMGRHETRPHPQASPAPAMQKKGQPGYPSSADYSQPSRAPSAYHHASDSKKGSRQAHSG----PTVLQPKPEAQAQPQMQGRQAVPGPQQSQPPSSRQTPSGTASRQPQTQQQQQQQQQQQQQQQQQQQQQQQQGLGQQAPQQAPS---QARLQQQSQPTTRSTAPAASHPAGKPQPGPTTAPGPQPAGLPRAEQAGSSKP-AAKAPQQGRAPQAQSAPG--PAGAKTGARPGGTPGAPAGQPAAEGESVFSKILPGGAAEQAGKLTEAVSAFGKKFSSFW", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88737-1", "uniprot_id": "BSN_MOUSE", "id": "O88737-1", "name": "Protein bassoon", "aln": "MGNEASLEGGAGEGPLPPGGSGLGPGPG----AGKPPSALAGGGQLPVAGAAR-AAGPPTPGLGPVPGPGPGPGPGSVPRRLDPKEPLGSQRTTSPTPKQASATAPGRESPRETRAQGPSGQEAESPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPS-QPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALS--PAHSPAKQPLGKPEQERSP--RGPGATQSGPRQAEAARATSVPGPTQATAPPEVGRVSPQ--PPLSTKPSTAEPRPPAGEAQGKSATTVPSGLGAGEQT--QEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPSPSKGQPKIVFSDASKEAGPRPPGSGPGPGPTPGAKTEPGARMGPGSGPGALAKTGGTASPKHGRAEHQAASKAAAKPKTMPKERASACPLCQAELNMGS-RGPANYNTCTACKLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPAPLPLPTPQQPPAGVPHRAAGAAPLKQKGPQGLGQPSGSLPAKASPQATKASPQATKASPQATKASPQTTKASPQAKPLRATEPSKTSSSAQEKKTVTSAKAEPVPKPPPETTVPPGTPKAKSGVKRTDPATPVVKPVPEAPKGGEAEEPVPKPYSQDLSRSPQSLSDTGYSSDGVSSSQSEITGVVQQEVEQLDSAGVTGPR-PPSPSELHKVGSSLRPSLEAQAVAPSAEWSKPPRSSSSAVEDQKRRPHSLSITP-EAFDSDEELGDILEED-DSLAWGRQREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPAR-ADMTDEEFMRRQILEMSAEEDNLEEDDTAVSGRGLAKHSAQKASARPRPESSQE----PKRRLPHNATTGYEELLSEA-GPAEPTDSSGALQGGLRRFKTIELNSTG-SYGHELDLGQGPDPNLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAETLDGGPTRLYKSGSEYNLPAFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEDMMRKAEMLQRQQGQVAGARGPHGGPSQPTGPRSQGSFEYQDTQDHDYGGRASQPVAESTPAGLGAAVYEEILQTSQSIARMRQASSRDLGFTEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTSTSSDSSGGRVIPDVRVTQHFAKEPQDPLKLHSSPVSSTLTSKEVGMTFSQGPGSPATTASP------TRGYMTPTSPAGSERSPSTSSTIHSYGQPPTTANYGSQTEELPHAPSGPPGSGRAPREKPLSGGDSEVGAPQPSRGYSYFTGSSPPLSPSTPSESPTFSPGKLGPRATAEFSTQTPSLTLSSDIPRSPGP--PSPMVAQGTQTPHRPSTPRLVWQQSSQEAPIMVITLASDASSQTRMVHASASTSPLCSPT-DSQPTSHSYSQTTPPSASQMPSEPAGPPGFPRAPSAGTDGPLALYG----------WGALPAENISLCRISSVPGTSR-VEPGPRPPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPVSGRQSTAVQPLVINLNAQEQTHTFLATATTVSITMASSVLMAQQKQPVVYGDPFQSRLDFGQGSGSPVCLAQVK----------------------------QVEQAVQTAPYRGGPRGRPREAKFARYNLPNQVTP-LARRDILITQMG-----TAQGVGLKPGPVPEP------------GAEPHRATPAELRSHAPPG---TRKPHTVVVQMGEGTAG--TVTTLLPEE----PAGALDLTG-MRPESQLACCDMVYKFPFGSSCTGTFHPAPSAPDKSVTDTALPGQSSGPFYSPRDPEPPEPLTFRTQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRLGQLFQGPGRDSAVDLSSLKHSYSLGFADGRYLGQGLQYGSFTDLRHPTDLLSHPLPLRRYSSVSNIYSDHRYGPRGDAVGFQEASLAQYSATTAREISRMCAALNSMDQYGGRHGSGSGGPDLVQYQPQHG-PG--LSAPQGLAPLRSGLLGNPTYPEGQPSPGNLAQYGPAASQATAVRQLLPSTATVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYVSGGVTAVPLTSLTRVPMIAPRVPLGPAGLYRYPAP-RFPIAS------SVPP----AEGPVYLGKPAAAKASGAGGPPRPELPAG----VAREEPFSTTAP-AVIKEAPVAPAPGPAPAPPPGQKP--AGEAVAGSGSGVLSRP--------------------------------ASEKEEASQEDRQRKQQEQLLQLERERVELEKLRQLRLQEELERERVELQRHREEEQLLVQRELQELQTIKQHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQLQQQLQLQLEEQKQRQKAPFPATCEAPSRGPPPAATELAQNGQYWP------------PLTHAAFIAVAG----TEGP---------GQPREPVLHRG-LPSSASDMSLQTEEQWEAGRSGIKKRHSMPRLRDACEPESGPDPSTVRRIADSSVQTDDEEGEGRYLVTRRRRTRRSADCSVQTDDEDNADWE-QPVRRRRSRLSRHSDSGSDSKHDATASSSTTAAATARAMSSVGIQTISDCSVQTEPEQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQAQGVAGPQLIGPTAISPYLPGIQIVTPGALGRFEKKKPDPLEIGYQAHLPPESLSQLVSRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQ-KQFIADSTLRQQTLPRPMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPP-NGLVRKVKRTLPSPPPEEAHLPLAGQVPSQLYAASLLQRGLAGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLAKDRGGRDYPPLRGLGEHRDYLSDSELNQLRLQGCTT---PAGQYVDYPASAAVPATPSGPTAFQQP--------RFPPAAPQYTAGSSGPTQNGFPAHQAPTYTGPSTYPAPTYPPGTGYPAEPG-------------------LPSQPAFHP-TGHYAAPTPMPTTQSAPFPVQADSRAAHQKPRQTSLADLEQKVPTNYEVIGSPAVTMSSAPPETGYSGPAVSGSYEQGKAPEHPRGSDRSSVSQSPAPTYPSDSHYTS-LEQNVPRNYVMIDDISELTKDSTPTASESQRLEPLGPGGVSGRPGKDPGEPAVLEGPTLPCCYGRGEEESEEDSYDPRGKSGHHRSMESNGRPS-THYYGDSDYRHGARADKYGPGPMG-PKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYPPPTVSSSLTSRGRKFQDEITYGLKKNVYEQQRYYGVSSRDAAEEDERMYGSSSRSRMASAYSGEKLSSHDYSSR-GKGYERERDTAERLQKAGSKPSSLSMAHGR-ARPPMRSQASEEESPVSPLGRPRPAGGALPPG-DTCPQFCSSHSMPDVQEH-VKDGPRAHAYKREEGYMLDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHTVSSS-QKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHTSAKEHRHHSDHGRHSGRHAGE---EPGRRAAKPHARDMGRHEARPHPQASPAPAMQKKGQPGYPSSADYSQSSRAPSAYHHASESKKGSRQAHTG----PSALQPKADTQAQPQMQGRQAAPGPQQSQPPSSRQTPSGTASRQPQTQQQQQQQQQQQ-------------GLGQQAPQQAPS---QARLQPQSQPTTRGTAPAASQPAGKPQPGPTTAPGPQPAGPPRAEQASSSKPPAAKAPQQGRAPQAQTTPGPGPAGAKPGARPGGTPGAPASQPGAEGESVFSKILPGGAAEQAGKLTEAVSAFGKKFSSFW", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9UPA5-1", "uniprot_id": "BSN_HUMAN", "id": "Q9UPA5-1", "name": "Protein bassoon", "aln": "MGNEVSLEGGAGDGPLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPG--PGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPS-QPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALS--PAHSPAKQPLGKPDQERS---RGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQ--PPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQT--QEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERA-ICPLCQAELNVGS-KSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKAS--------------PQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPH-PPSPSEIHKVGSSMRPLLQAQGLAPS-ERSKPL--SSGTGEEQKQRPHSLSITP-EAFDSDEELEDILEEDEDSAEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMRRQILEMSAEEDNLEEDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEG-GSAEATDGSGTLQGGLRRFKTIELNSTG-SYGHELDLGQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYG-QAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPT-ETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYG----------WGALPAENISLCRISSVPGTSR-VEPGPRTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEH--TFLATATTVSITMASSVFMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVK----------------------------QVEQAVQTAPYRSGPRGRPREAKFARYNLPNQVAP-LARRDVLITQMG-----TAQSIGLKPGPVPEP------------GAEPHRATPAELRSHALPG---ARKPHTVVVQMGEGTAG--TVTTLLPEE----PAGALDLTG-MRPESQLACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADAAPPGQSSSPFYGPRDPEPPEPPTYRAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRIGQLFQGPGRDSAMDLSSLKHSYSLGFADGRYLGQGLQYGSVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGPRGDAVGFQEASLAQYSATTAREISRMCAALNSMDQYGGRHGSGGGGPDLVQYQPQHG-PG--LSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVPLGPTGLYRYPAPSRFPIAS------SVPP----AEGPVYLGKPAAAKAPGAGGPSRPEMPVG----AAREEPLPTTTP-AAIKEAAGAPAP----APLAGQKP--PADAAPGGGSGALSRP--------------------------------GFEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERERVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQLQQQLQQQLEEQKQRQKAPFPAACEAPGRGPPLAAAELAQNGQYWP------------PLTHAAFIAMAG----PEGL---------GQPREPVLHRG-LPSSASDMSLQTEEQWEASRSGIKKRHSMPRLRDACELESGTEPCVVRRIADSSVQTDDEDGESRYLLSRRRRARRSADCSVQTDDEDSAEWE-QPVRRRRSRLPRHSDSGSDSKHDATASSS-SAAATVRAMSSVGIQTISDCSVQTEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQAQGVAGPQLVGPTAISPYLPGIQIVTPGPLGRFEKKKPDPLEIGYQAHLPPESLSQLVSRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQ-KHFTADSALRQQTLPRPMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPP-NSLVRKVKRTLPSPPPEEAHLPLAGQASPQLYAASLLQRGLTGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLAKDRGGRDYPPLRGLGEHRDYLSDSELNQLRLQGCTT---PAGQFVDFPATAAAPATPSGPTAFQQP--------RFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPGASYPAEPG-------------------LPNQQAFRP-TGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTS-LEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPG-SSGRPGKEPGEPGVLDGPTLPCCYARGEEESEEDSYDPRGKGGHLRSMESNGRPASTHYYGDSDYRHGARVEKYGPGPMG-PKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYPPPAVSSSLVSRGRKFQDEITYGLKKNVYEQQKYYGMSSRDAVE-DDRIYGGSSRSRAPSAYSGEKLSSHDFSGW-GKGYEREREAVERLQKAGPKPSSLSMAHSR-VRPPMRSQASEEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHSMPDVQEH-VKDGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHG-DHGRHSGRHTGE---EPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSG----PAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQ-------------------GLGLQPPQQALT---QARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKG-TAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADGESVFSKILPGGAAEQAGKLTEAVSAFGKKFSSFW", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B2S6-1", "uniprot_id": "A0A8M2B2S6_DANRE", "id": "A0A8M2B2S6-1", "name": "", "aln": "MGNEASLEGEGQPG--QPGGAVPAAGAP------ASISAPAGGGQLHKP-----SNGAPAGGMG----TGHGPGMNSIQGKPNQTDPS-----MGPKPGGPPGAGPGPGAP--TQPQGPS--QSQAARKNLQVDVGGSKGG---PVSPG-SSAPTSPYSLPQIAPMPSSKLCPVCKTADLTGTTDGQPNCNKCTQCRSMVCNQCGFNPNPHLTEVQEWLCLNCQMQRALGMDMETP-RSKSQQQIHSPSQPSKPSPQPVTQPTAQPQPQPQPQPQPQPQPQPQPQHPPEAKKQTVPQAVPQSKPPAPGAVPLPGMAKAPSQPDLSRSGPGFLPQIPRQDQTRSAGSSPSRQPPPPEQPFGKLFGFGASLLNQASNLMSVDPVQTAPPTQPPTSPKP------PQKQPGP------PGPGPGPAVGTKPTAQPGP---------------PRQ---------DIPAKPKVC-------CPLCKAELNVGDPAKTPNYNLCTQCHTQVCNMCGFNPTPHLTEKKEWLCLTCQTQRAMSGSLGDITPPVPPSVGSP--RLPGPANQQQQQRGSSQQASLRPTGPQQQKPAGAQVSVPFSPVKQG-------------APQSK--GPSQQLPATKTDTKKQDQGNNKKQVMSKTEKDGDIKASSKKGTSDKKDEKKSSGIQKSKQDDDSN---------------KSSTQSLSDTGYSSDGISSSQSEITGLIQEDSMKLNERGVTDQRSPPSPSELTKLESSMRPLLESHTGTGQGQHRDGR------DNADQQRPRSLSITQDQEFESDE-------------------------EASDDLSCKLRHDYVEDSSESGLSPLPPRQKKSQKELTDEEFMRRQILEMSADEEDTADTEGHVKSKRSHKHSGDLGKER--------------RRLTQQSSSFEEDSKSADNYKSAEADDMMASQGGLRRFKTIELNNTN-SFNRDMELSTDHD---LREPELEMESLTGSPEERSRGEYSSTLPATTPSYTSGTSPTSVSSMEDDSDSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEDELREEEELLREQEKMRDLEQQRIRSTARKTKRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSP--SMDSEAEGFEMG-SKLYKSGSEYNLPTFMSLYSPTEKTSAVSPS-TADKSLKSAEEVYEEMMRKAEMMQKQQQRAP------GGPGQQNQ--------------------------------------ERMLQTDK----------------------KQHLDSGTT----------SLSPGTSPTQISAPVSFSGNDPS----GRGAQRMQSTQSHSQS-------------------QVRMNNQTSKGG---------------------------HSGSPQSQIR---QPAPTQ---------PQGRPGVQGTAQGQVPDPGASS-------LTSKMFSYFKGSSPSTSPST---SPTHSP----TRGPAPCTISTVAPTQTS-------------------QSPHRSGAPRLARQQSSQDSPVIVITLGSGTSSQTKPATVNSSTSPLSSPTKDSQKTIYQTQHTTTKSPTSPQKYPTHQTSQHVLQRAQISERVSLPASTAISAGAQSSGSLPAGNISLCRISTVPGTSRVVEQGTIAPGSNIVDLRAPMKPAPIIMTDQGMDLTSLASDARRYSLDSETAPSR-HTAVQPLIMNLNSQAQPQVTTTTPTTVSVTVAASMFISQPKQPVVYGDPLQNRVDFGQGVGSAVCLTQNRPLITDPSIPKIDACLENLGIQQQQLQKQQQKLQQQQELLEQQLQQHHQNASFARYNLANQVQPILLKKDLVVSQNASGGTQTAVSSIAKISPLPPPPLSCSASTTPTLGHDIYGGVALELKNKPAVINLSTVNPQVMMVQLEENSTQGATVTQLVKREEPPPPVDVLDLTGQIKPENQLACCDVVYKLPFAGSCSGPFS------QRGKTTPSEPPAEPTQVHG----QQSQPINDAYQTATIQATADESKSFTLPPAGRLPPSMSDNNLAGSSLQYYQR------TDPG-DLAVDLSTMKQAYEAG-----YLGMGSQYGSYTDLRHQGSDSAPPLPLRRYGSMSNINAEYGYPPR-DLGGFQESNLAQYSATTAREISRMCAALNSMEQFGSRYTS---TPELLQYGAGRGGPAGRLNLQQGLASIRANLLYG---PDGRPTVHGQTLTNLINARQASLRSLYPPAG--RTADGMIYSTINTPIASTLPITTQPAPVLNPMLRG-AYGPYTSGGVTAVPLASLTRLPQVTPRMPLNAQAPYRYPPPNQFSATAPETLSGSVPPSSTSQEVPVYLGKPTAPGSMSTNASQKSSQPVSNMGMQSIQPAHTSMVPVQSVVNAPITHMPVDSTTMQLQSQPQTQAQSLVKGQEQTQSQPQTQPQPLTLPQKQTQAITRVFPDASASTTITTSADTEKEKEEERLRQQQEQLLQLERERVELEKLRQLRLQEELERDRVELQRHREKEHLLMQREIQELQTIKQQVLHQQQAERETQLVMQREQLAQQRMQLDQIHSLQQQLQQQLEEQKRQKTAAIEAAAVAAAAEAAAASAAAAAAATTAQGAMQGVMVGGTTPQTISIIYDQSGRIIPQEGQSVQLLPCADGQVVQAVVSTRPLPSSSSEMSLKNSE--EHGDRIMKKQNSMPRLRNGSEDES------VKRIADCSVQTDDEDAEDK-LMSRRRRTRRIADCSVQTDEEDQGEWDNQPIRRRRSRYSKHSEPAAETKSDAS-------------KSSIAIQTTNDSSCQTESDQLGRISPAIHITMAETSKVELLHYISAPERTHKGESLACQTDPEAQSHGVVAPQLSVPTTVSPYSTSLQLVGATPT-KFERRKPDPLDIGYQQAQQQ---NESPSRQPPKSPQVLYSPVSPLSPHRMLETTFASSEKLNKAHVTPQQKAFTTESPQRHQTIPRPIKSVQRSMSDPKPLSPTSEDPAKTKFSLYQSQASPASQMSALQQQNAMMRKVKRTLPSPPPDESPLPIMTPAIPHIYSSPGVSQRVLPRTAQGAMKAGLLSELK----AVEQESTKLRKQQAELEEEEKEIDAKLRCLEMGITQRKETRVKERERRELAYLRCIGDARDYMSDSELNNLRLAGVAPGTYEENGMLSRPSTAPLSQFTSDLNASQYPPTSSYVPYQYPQPQPTPTQPPTATYQIGFQPAPYPTSSQPQPGTFQPHPPQPSSYQTPGPYQTHNYGQPTYESDLGLQQPSHQGFQPPTAPLAGQTLPYPAQSMSFQPQGDMLSAHQRPRQTSLADLEQKLPTNYEVISNPSIPVATSAQDTGFSG-VYSSPLNNAYGQYRPSDQPLTERIPSPSSGYGTDGVYATNLEQNIPRNYVMIDDISELTKENMGSSDMAR----LGYGSENGPRGPTYGD-------------------GSENLYG-RTSNTYQGGVDSHGHPITSGSGGSGYYYDDYKHSSRSSGGMGSQKHSSKNLAP-AVSSKRSKHRKQGMEQKISKFSPIEEARDVESDLASY------TMTTSTGGSCTVVSRTGVKKG-YDQQKYYGS--REALEEDDRLYG-SGRSRS-TGYGMDKISSRDSSGYRSKSYER--DAMERSQRG---------THGRSGRPSMRTQNSEEESPLSPVGKPMGIGRGSVPD-DVRNQYGSSHSLPDVQDHHMRDIPKSHVYKPDDPYLADDMHCAVSDSEAYHLGQEETDWFEKPREARS---KHHGSGSHSSS-SRRGNVKHTYHDYDEPPEEDLWPQDEYGHQRHSSSTSSREHRHHGSSSGRHTSSRHTTDDPRSSRSSRSHPKDPSIRSDGRTTSSSTQKRSSDPRSGSHRDSGEYSRDPSGHHHGSSGQRGQRQPGSSRRQEPSSGSRPQQGLGEQQLQSQQGQQRSSAGQQVSAKQTGSLPPETGQQGQQQLGQTTRTQQQPLQHPGQQPATTMGASQPTTTAAGMGTGTTQQQQSKPGQAPAQARQQPGGPPTAQPAAAMAKSDIAAPAPAPAPAPTP--AVAIGSKAAPQAAKPPQIPATGIGSKAAPRPGGIGSAAQQPAEGENVLTKILQGGAAEQAGKLGDAVSALGKKFTSFW", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****.**** . * ***: ..*. . ** ****** . : .*. * * .* *** .* : : .:* .*.* ...: ** :* *:.** : :::..*:.**** .:.* .***. .*:******:*****:***.***:***:***.*.. *** *.****:. **************:*:***************** *. *******:***: . *: .*..** .:*: : . : .*. .::. *: :** .. : ** * *. . .::*. :.. * :. : .:* .. .*. *****:*****.***.****:* : .*:. * ..*:.** ***** *.. *:* .: ** *:: . .****. ****:****:*. ..*** ** *: :**.:*********.**.*****.***:* :.****: :* *: .* * * : .. *. :*:*. *.: .... . * . **:* .:: :..: :*: * : :.*. : ..: * .*. : . :: : *. : .. . *.************:*********::*:: :*:. ***. : ******: *: **:** *::: : . : . : :::**:**** : *:*** *:***:..:***********.*******: ::***:***********:*:: : : ...: **. : . * ***.::::: *: . : :* : ********** **.*. :. .::*. . * ***************:*****:******:************:**:*:***************************************:****************::************:***************************************************** *:***** :: * ::***********:**** ****..*. *.: ::.:.******.**:******::*:** :.. ***.* . *.:***.: **.*:: :: .*:*******::*****. .* ** :: ** .::. :: * . . * :* *..* : :...* *:. .* .:.:. .* :.. .*: :*** .***. ***: ***.** .*..* : .* : : :* *:***..:***. *:***::*.:****.*.:****: . ..:*****.*** ::* : : .:**. * :. *. .. * . ::* . *:*** ********:****** ** *. .**: :****:.:**:***:*********** :**:*.* :. ..* ******::***:* : . :*.****:*:*:*::::* ********* *.*:***** **.***:* : * : * . : : ::*.******.*** * * ::*::::* . ** . * .*:* * * : : ... **: :. : :*:.::**: *.:: *** *: .* *...***** ::**.:*****:.**:**..**:*.* ::. : .: * .. .:. : .:* . * .. .. :*.:.:. .*** .****.*** :.*:*: : .** * *:***::*::*. * *** * **** ***** . : ***:* *.*:*** ::: * ** * ****:.**********************:*:*.*: . *:*: * . :* *. *. *.*..:*..** . *:*:*: . : . .: :::*.* *.:. *:**************:*********.**.**:** * ** ***:*****:****:* ::**:**.. . ****.* :*. :: ::** * *******:*. : .:... :.. *.. : : . .: .* : :*. : * : .:* .:: . . . .:* :.*: .:*:* *:*****************************:*********:*:**:***:*******::**:*** **::*:.:*********:**:**:.****** ******:::.*.: *:. *.. .. *:: * . * * : : :* ** ** :.*: ****:*:***:..* * . :**::******:..* ** *:****.*******:.*.: *::****:** ********:**..:*: **:****** .:**:..:::* :*: **:.*** .*.* ***.:** *:******* * .***:::******:* :********:*:.*::**..*** **::*** ..:*:* . . :**::*****:**** .: **********************:*:*:*****:******:** * * ::*. *:**:***:*::***:*********:*:.** :***** *.. .**:*** *.::************:*: **: . .::*::. :.: : *: * **.** **. **:*******:****:**********: **:*******: .*:* *: . ** :*: ***:******:*** * :. . :. *::*. . .*. .* * * :: . . : . .. * ** . ** . *.. . ..** .. ** *.: .*:* *. *. * .:** * .* :. *:************:*******..* :.::::. :*.:** . *. ::. * . **:. * :*. *:: ****:***************:. :: :: ** * .* * *: ..*: *. * .. : .::*:*:* : ... * .. : .. ..* ** **.**.*** *:*************************:********* : .* . . *:**. *:**:*** *:: * *:*:** *.*** :.*. :*:**:* *. .*.*** :: :* *:. :*.* **.**:* ******:**:*:* * *. *. *: ****:****:* ::* *::*.** :: *: ** **.*****************:***:*** :***. : *** .:** .:*:**********.***:** * **:*:.. *. .** ****:.. . *:::. . . *.. :.:.:.: :..:* * : .: ** .*.:**.*..::*.**. :. *: . : .: *:*.:*. .. .* *::* * ... * *** :* . * : : . * *.. . :..* * .:*.* * . *::* . . . * . : ... * * . **** .* .:* . * * ..*.* *:**.*::*** ********** :****:****:***", "identical_positions": 1680, "similar_positions": 1046, "identity": "40.12%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120703-10", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LF28-1", "uniprot_id": "A0ABK0LF28_RAT", "id": "A0ABK0LF28-1", "name": "", "aln": "MDPPEKDDKAKPRDEDSEKEQISESTMTPPRKDDEAIPKDEGSEKEQTTETKMTPPEKDAEMVTKVKGPEQEQTTESPTTPPKKDDKATPKEEGSEEEQKPPESPTTPPKKDDKATPKEEDSEQEQKSPESTITPEKDDKGTQKDEGSEEEQPSSESPTTPPKKDDKATTKEEGSEEEQKPPESPTTPPKKDDKATPKEEGSEKEQKSPESTTTPPKKDDKATPEEEGSEKEQKSPDSPTTPPKKDDKATLNEEGSEKEHKSPESTTPPKKDDKATPKEEGSEKEQKSPESPTTPPKKDDKATPKEEGSEEEQKSPESTTPPKKDDKATPKEEGSEKEQKSPESPTTPPKKDDKATPKEEGSEEEQKSPESTTPPKKDDKATPEEERSEKEQKSPESPTTPPKKDDKATPKEEGSEEEQKPPESTTPPKKDDKATPKEEGSEKEQKSPESPTTPPKKDDKATPKEEGSEEEQKPPESTTTPPKKDDKAIPKKEGSEEEQISPESKTTPPEKGAKMIPEFQGPEQEQTSESPTTPPKKDDKAIPKDEGSEKEQTSESKITPEKSDKASPKDKGSEEEQTSESKITPPRKDDKAIPKGERSEEEQTSPESKITPEKSDKASPKDKGSEEEQTSESKITPPRKDDKAIPKEERSEEEQTSSESTTTPPKKDDKAIPKKEGSEEEQISPESKTTPPEKGAKMIPEFQGPEQEQTSESPTTPPKKDDKAILKDEGSEEEQISESKITPPRKDDKAIPKEERSEEEQTSSGLAEERIVTPEKHDKATQKDQGSEEEQIPESTTTPPEKDDEAIPKDEGSEEEQISDYKAHVIAKFDTSVDLHCDGPEMKVLSDAFKPHQKTFRPHTIILHGRPGVGKSALARSIILGWAQGKLYQDMSYVFLFSVREMKWTEK--SSLAQLMANEWPHSQAPVTKIMSQPERLLFVIDGLDDMDSALQHDDMTLSRDWKDKQPIYILVYSLLRKALLSQSFLIITTRNTGLENLRSMVVSPLYILVEGLSASRRSQLVLENIPDDHQKIQVFHSVIENHQLFDQSQAPSFCSLVCEALQLQEKLGKRCTLP-----CQTLTDLYATLVFHQLTSR-----GPSQRALSKEEQITLVGLCRMALEGVWTMRSVFYDDDLKSY---SLKQSEISALFHVNILLQVGHSSEQCYVFFDLSLQDFFAALYYVLEGLGEWNQYFSYITNQRNIMEVKRSSDSHLLEMKRFLFGLMNKDTLKTVEVLFRCPVTPPIKQKLQHCLSLIGQQVNGSSPMDTLDAFYYLFESQDEEFVHMALKSFQEVWLLINQKMDLMVSSYCLQQCQNLKAIRVDISDLFSVDNTPKLCPVALQKTQCKPLIIEWWENFCTVLSTHPNLKTLDLGHSILNEWSMKILCLKLRNSSCSIQNLTFKNSEVVSGLQYLWMLLVSNRNLKYLNLGNTPMKDDDIKLACEALKHPSCSLETLRLDSCELTLTGYELISKLLLSASSLKCLSLARNKVGVKSMTSLGEALSSSTCTLQKLILDGCDLIPVSCHMLTSALSSN-RNLTHLCLSNNSLGTEEVQQLCQFLKKPECALRRLILNHCNIIKDAYGFLALILANNRKLTHLSLTMNPVGNSAMKLLCEALKEPTCYLQDLELVDCQLTENCCEDLACMITTT-KHLQSLDLGNNALGDKGVITLCKGLKQSSSSLRRLGLAACGLTSKCCEVLSSALSCNPYLNSLNLVRNDFNTSGMLKLCSAFQNPASNLWIIGLWKQQFYAQVRRQLEEVQFIKPHVVIDGDWYSIDEDDRNWWKN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AB32TPT2-1", "uniprot_id": "A0AB32TPT2_DANRE", "id": "A0AB32TPT2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDNSKGGPPPNFSEKTPSSVKRFFHLGKSKHPPSNLREKTPSSAES-------------------FEYESPDSKNKTHRSRKSFTDNLLKIFQNLESKMIKFLKKELQKFRKILQEENRQE-----------------------------------------FVKDFN-----------------ENRSIIKEAALELTLFFLREMT----------------QDQAADTLEDELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVN---TEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDEQIRAVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLLFREMNLKEKERQSLKDLITQFFPETKG-LNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRG-FNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTPDVSWDPNLILS-LGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALY-------------QHLILDNVKTQAEKSRDESMIDYLKTAVDKALESENGHLDLYLRFLLSLSLQSNRQLLRGLLTQQDD---------------RDQSNEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLS--------------GGSLSSARLSPAQWSALVFVLLTSEEELEKFELQKFQRSDECLIRLSAVIKTSKRALLQGCNLTVQCCESLS--SVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLSGCMVTEEG---------------------------------------------------------CGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGEEKRITAGIHKYVCF---------LTLDPNTANTQLILSEENREVKSVRENQPYPDHPDRFDYWPQVLCRESVCGRCYWEIDWSGDDHG--------VFISVSYKSIRRKGTGVECGFGSNAQSWSLLCSSSSFSLRHNNTHTDLPVELLSRRIGVFVDHSAGTLIF----YNIYRDTMSLIHSVQTTFTEPLYPGFRIYYGSSVKLS---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . *: . :.* :. .. . .*..: ..:.*. * : *** :* .:: ..* .*.: .: .::** * **:** ...:* *: ..: . :: ... *. :*: : : * :.*:.* :: :*: ::::*:*: . * : ::* ::*::. * :* :. : : . .:* *. * :. :* :: : :*:.*: . * * ::::: * . .. *:. :: : :::: :* .*:***. .:.::*.**:** **:*::* : .***: .** .** :*::: :*.::. :. * ::**::****: .*:. . .** .. .: :*: .*:: **..::: **:* :. .:: : :. * : :. :::.: . :.:.*::* :::. : :.:.** .: * ** : . .** ** :*. :***::*: :: .*: . * . :* : :: * * ::*:: : . :**:.***. * * *.: : :.* * *:.**:*:*:**** .:: :. :.::* *. ::: : .. :. ::: :* :: .::.: * .*: ** : ..*.:* : :*. * * ::.::*: . *:: ** *: .:* . . :..: :* . .:*::. :*:.::* : .: .: *. ::.*. :: : . : ..*. :* ** *: *:*.*. ::*..:** .:.** *.******..* :* * * :*:***:** :* .* ** * * . *: *.: *:.*: :* :* *:* : : : *: : **::* .: :*.* :* .. :: * : :: * :. : .:* ..: * :. * .*:** * .. .. .: * *...: * .:.*: .. : : ..* : ::. *: ::* :. :..** .. : * ... : ", "identical_positions": 219, "similar_positions": 431, "identity": "12.2%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120703-37", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q62513-1", "uniprot_id": "ZN260_MOUSE", "id": "Q62513-1", "name": "Zinc finger protein 260", "aln": "-----------------------------------------------------MLESLQ-----------------------------------------------------------------------------------------------------------------------------PESHLL-HDEPDPGESVYECNECKETFSLEQNFVEHKKTHSGEK-SPECTGCGEESSQASSLTLHLRSRPRRESYKCGECGKAFSQRGNFLSHQKQHTEERPSESKKTP---VPMTTTVRNQRN-TGNKPYACKECGKAFNGKSYLKEHEKIHTGEKPFECSQCGRAFSQKQYLIKHQNIHSGKKPFKCNECGKAFSQKENLIIHQRIHTGEKPYECKGCGKAFIQKSSLIRHQRSHTGEKPYTCKECGKAFSGKSNLTEHEKIHIGEKPYKCNECGTIFRQKQYLIKHHNIHTGEKPYECNKCGKAFSRITSLIVHVR-IHTGDKPYECKICGKAFCQSSSLTVHMRSHTGEKPYGCNECGKAFSQFSTLALHMRIHTGEKPYQCSECGKAFSQKSHHIRHQRIHIH----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q62981-1", "uniprot_id": "ZN260_RAT", "id": "Q62981-1", "name": "Zinc finger protein 260", "aln": "-----------------------------------------------------MLESLQ-----------------------------------------------------------------------------------------------------------------------------PESELL-HDEPDPGEKVYECDECRKTFSLEQHFVEHKKTHGGEK-SPECTGCGEEFSKASSLTRHLRSRSRRESYKCGNCGRTFSQRGNFLSHQKQHAEERPSESKKTP---VPMTTIVRNQRN-AGNKPYACKECGKAFNGKSYLKEHEKIHTGEKPFECNQCGRAFSQKQYLIKHQNVHSGKKPFKCNECGKAFSQKENLIIHQRIHTGEKPYECKGCGKAFIQKSSLIRHQRSHTGEKPYTCKECGKAFSGKSNLTEHEKIHIGEKPYKCNECGTIFRQKQYLIKHHNIHTGEKPYECNKCGKAFSRITSLIVHVR-IHTGDKPYECKVCGKAFCQSSSLTVHMRSHTGEKPYGCNECGKAFSQFSTLALHMRIHTGEKPYQCSECGKAFSQKSHHIRHQRIHIH----------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3ZCT1-1", "uniprot_id": "ZN260_HUMAN", "id": "Q3ZCT1-1", "name": "Zinc finger protein 260", "aln": "--------------------------------------------------MIGMLESLQ-----------------------------------------------------------------------------------------------------------------------------HESDLLQHDQIHTGEKPYECNECRKTFSLKQNLVEHKKMHTGEK-SHECTECGKVCSRVSSLTLHLRSHTGKKAYKCNKCGKAFSQKENFLSHQKHHTGEKPYECEKVS---IQMPTIIRHQKNHTGTKPYACKECGKAFNGKAYLTEHEKIHTGEKPFECNQCGRAFSQKQYLIKHQNIHTGKKPFKCSECGKAFSQKENLIIHQRIHTGEKPYECKGCGKAFIQKSSLIRHQRSHTGEKPYTCKECGKAFSGKSNLTEHEKIHIGEKPYKCNECGTIFRQKQYLIKHHNIHTGEKPYECNKCGKAFSRITSLIVHVR-IHTGDKPYECKVCGKAFCQSSSLTVHMRSHTGEKPYGCNECGKAFSQFSTLALHMRIHTGEKPYQCSECGKAFSQKSHHIRHQRIHTH----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "L7N267-1", "uniprot_id": "L7N267_MOUSE", "id": "L7N267-1", "name": "", "aln": "---------MMRILSLPTENAVTYYDVLVSFTQEEWALLDPS---QKSLYKDVMLETYRNLTAIGYNWEEDN---IEEDCENSGR-------PTRHLQRDGPSNTGEKPFECIQYDGAF--------------------------------------------------ARNHHQLHKDTGSFMSYTDRQIHRRPHTEEKVYDGNQCGKTFSCHNHFEIRKGTYTGEK-PYECNQCGKAFARHSNLLDHKRIHTGEKPYKCKQCGKDFTHHSTLHIHKRIHTREKTYKCNQC----MTIAHLQCHKITHTGEKPYACKKCGKTFAYHKTLQIHERTHTGEKLYQCNQCAKAFPYHRTLQIHERTHTGEKPYECNQCGKAFACLRNLQNHKTTHTGEKPYECNQCGRAFRQYVYLQCHERIHTGEKPFECNQCGKAFARHSTLQRHKRTHTGEKPYECNQCGKAFACPRYLQIHKRTHTGEKPYECNQCGKAFACHRYLQIHKR-THTGERPYECNQCGKAFTCRSNLQIHKRTHTGERPYECNQCGKAFTCRSNLQIHKRTHTGEKPYECNQCGKAFTQFFPLKRHEITHTKEKPYECNQCGKAFTRHSTLQIHKRTHTGEKPV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9PZP6-1", "uniprot_id": "E9PZP6_MOUSE", "id": "E9PZP6-1", "name": "", "aln": "---------MMRILSLPTENAVTYYDVLVSFTQEEWALLDPS---QKSLYKDVMLETYRNLTAIGYNWEEDN---IEEDCENSGR-------PTRHLQRDGPSNTGEKPFECIQYDGAF--------------------------------------------------ARNHHQLHKDTGSFMSYTDRQIHRRPHTEEKVYDGNQCGKTFSCHNHFEIRKGTYTGEK-PYECNQCGKAFARNSNLLDHKRIHTGEKPYKCKQCGKDFTHHSTLHIHKRIHTREKTYKCNQC----MTIAHLQCHKITHTGEKLCEYNQCWKAFAYHKTLQIHERTHTGEKLYQCNQCAKAFPYHRTLQIHERTHTGEKPYECNQCGKAFACLRNLQNHKTTHTGEKPYECNQCGRAFRQYVYLQCHERIHTREKPFECNQCGKAFAHHSTLQRHKRTHTGEKPYECNQCGKAFACPRYLQIHKRTHTGEKPYECNQCGKAFACYQSFQIHKR-THTGEKPYECNQCGKAFACNRYLQIHKRTHTGERPYECNQCGKAFTCRSNLQIHKRTHTGEKPYECNQCGKAFTQFFPLKRHEITHTKEKPYECNQCGKAFTRHSTLQIHKRTHTGEKPV--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9QAG8-1", "uniprot_id": "ZN431_MOUSE", "id": "E9QAG8-1", "name": "Zinc finger protein 431", "aln": "-----------------MVDALTYDDVYVNFTQEEWALLNPS---QKSLYKDVMLETYRNLNAVGYNWEDSN---IEEHCESS-----------RRHGRHERNHTGEKPYEGIQYG----------------------------------------------------------------EAFVHHSSLQMRKIIHTGEKRYKCNQCDKAYSRHSILQIHKRTHSGEK-PYECNQCGKAFTQHSHLKIHMVTHTGEKPYKCDQCGKAFAFHSTLQVHKRTHTGEKPYECNQCSKAFAHHCHLRVHKRIHTGEKPYKCDQCGKAFVGQNDLKRHERVHTGEKPYKCNECGKAFVCNASLRTHKTTHTGVKPYECKQCTKSFASHGQLQKHERIHTGEKPYKCDQCGKAFASHDKFQKHERIHIGEKPYKCKQCTKSFASHDKLQKHERIHTGEKPYECKQCTKSFASHNKLQKHERIHTGEKPYKCDQCNKAFVYESYLQVHKK-THTGEKPYKCNECGKAFARHSHLKVHKITHTGEKPYKCNQCGKALAYHSTLQVHQRTHTGEKPYECEQCGKAFANQSYFQVHKRIHTGEKPYKCDQCGKAFVGSSDLKRHERVHTGRETLQM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A087WNP5-1", "uniprot_id": "A0A087WNP5_MOUSE", "id": "A0A087WNP5-1", "name": "", "aln": "------------------MDAVTYEDVYVKFTHEEWALLDPS---QKSLYKDVMLETCRNLTAIGYKLQDDN---IEEHCPSS-----------RGCGRYN--IYGYKPCEHKGYGK-------------------------------------------------------------KQCTFAQKRFLQTYERICSEEKPYECNQCSKAFANFRSLQKHEKNHTREK-PYECNHCGKAFPSRSALQIHQRTHTGEKPFDCSECGKAFARHSNLDIHKRTHTGEKPYDCNECGKAFSTRSHLQIHEIIHTGEKPYVCNQCGKAFAYRSNLEAHEKTHTGEKPYECNQCGNVYASRSSLRNHEKHHTGEKLYGCNQCGKAFARRSSLEIHERTHTGEKPYVCNQCCKAFARRSSLQIHERSHTGEKPYECNQCGKAFASRTSLQNHEKHHTGEKPYGCNQCDKAFELKCDLQIHERIHTGEKPYVCNQCGKAFVSRRYLRNHEK-HHTLEKLYDCSQCGKSFAIFRYLQKHKKTHTGEKPYKCTHCGKAFAYRSNLYRHERSHTGEKLYECNECGKAFAYHTSLHNHKKCHIGENPYECN---------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2ANU7-1", "uniprot_id": "A2ANU7_MOUSE", "id": "A2ANU7-1", "name": "", "aln": "------------------MGVVTYDDVHVNFTQEEWALLDPS---QKNLYRDVMLETYRNLAAIGYSWEDHN---PEEHFQSS-----------RRHGRLEKSHIEEKPSEFTQCGK----------------------------------------------------------------VIAYQSHPQGHQQIHTGEKPYECEQCGKSFVCQSGLQQHKRTHHGEK-SYECNQCDKAFALLCHLRGHQRIHTGEKPYECNQCDKAFACQTSLLYHKRTHSGEKLYVCNECGKAFVLQSYLQIHKRTHTGEKPFGCDQCDKAFAQNSHLLTHKRTHTGEKPFGCDQCDKAFAQNSHLLTHKRTHTGEKPFGCDQCDKAFAQNSHLLTHKRTHTGEKPYECKQCGKAFGFQSGLQKHKRTHTGEKPYECKQCGKAFGYQSGLQKHKRTHTGEKPYECNQCDKAFACQASLLNHKRSHTGEKPYECSECGKAFVLHSYLQIHKR-THTGEKPFECDQCDKAFARNTLLLKHKRIHTGQKAYGCKQCGKAFANHSNLQVHKRTHTGEKPYECKQCGKAFGCQSGLQYHKRTQHIQERNPMTVINVI----------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "F6ZS36-1", "uniprot_id": "F6ZS36_MOUSE", "id": "F6ZS36-1", "name": "", "aln": "-------------------GRVTYDDVHVNFTREEWALLDSS---QKNLYKEVMLETYRNLAAIGYVWEDHN---TEEHLHIS-----------RRYGRHERSHTEQLLSEFIQCDK----------------------------------------------------------------AFAFQSHNQRQERIHTAETPYECNQCGKSFARKSHLLRHKRTHTGEK-PFQCYQCGKTLARNTHLLQHKKVHTGEKPYECKHCDKASVCHIGLLYHKRTHAGQRPYEWNECGKSIVYHSCIKQCKRRHTGEKPFECNQCGKSFARKSNLLRHKRIHTGEKPYKCDQCGKDFASPSSLKCHKRVHTGENPYECKQCGKAFARLSILRTHKRTHTGEKPFECNECGKSFARKSHLLRHKRIHTGEKPYKCDQCGKDLACPNSLQYHKRVHTGEKSYECKQCGKAFAFSTSLRIHKRTHTGEKPYECNQCGKAFSSPSGFLYHKQ-THTGERPYECNECGKSFIHRSNFQMHKRTHTGEKPFECDQCGKSFAQNTYLLQHKRVHTGEKPYECKHCGKAFAYSNNLRVHIRTHTKYLVW------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "K7N6H3-1", "uniprot_id": "K7N6H3_MOUSE", "id": "K7N6H3-1", "name": "", "aln": "------------------MNAVTYEDLHVNFTQEEWALLDPS---QKKLYKHVMLETYRNLNAIGFNWEAQN---IEEHCQSS-----------RRHRRCERSQSAEKPSEYTQRDK--------------------------------------------------------------AFALSAHSHAQRHERIHTEKIPSEDIHCVEDVLPYTSLQVHKRTQTGQK-PYECKQCGKGFAKPSHLKRHERYHTGEQPFTCNECDKVFSFKHHLQTHISIRTGEKPFKCNLCDKSFSKHNHLQSHRRTHTGEKPYKCDQCDKAFSEKCNLQTHIRIHSGEKPYKCDQCDKTFSEKCHLQKHIRIHTGEKPYKCNQCDKAFSQYNTLKTHRRTHTGEKPYKCNQCDKAFSQYGHLQTHRRTHTGEKPYKCNQCDKAFSQYNTLKTHRRTHTGEKPYKCNQCDKAFSEKCSLQRHIRIHTGEKPYKCNQCDKAFSQYSTLQTHRR-THTGEKPYKCNQCDKAFSQYSNLQTHRRTHTGEKPYKCNQCDKAFSMKCNLQNHVRIHTGQKPFKCNQ------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PDB4-1", "uniprot_id": "ZN880_HUMAN", "id": "Q6PDB4-1", "name": "Zinc finger protein 880", "aln": "---------------MLRRGHLAFRDVAIEFPQEEWKCLDPA---QRTLYREVMVENYRNLVFLGICLPDLSVISMLEQRRDPRNLQSEVKIANNPGGRECIKGVNAESSSKLGSNAGNKSLKNQLGLTFQLHLSELQLFQAERNISGCKHVEKPINNSLVSPLQKIYSSVKSHILNKYRNDFDDSPFLPQEQKAQIREKPCECNEHGKAFRVSSRLANNQVIHTADN-PYKCNECDKVFSNSSNLVQHQRIHTGEKPYKCHECGKLFNRISLLARHQRIHTGEKPYKCHECGKVFTQNSHLANHHRIHTGEKPYKCNECGKVFNRNAHLARHQKIHSGEKPYKCKECGKAFSGGSGLTAHLVIHTGEKLYKCNKCGKVFNRNAHLTRHQRIHTGEKPYECKECGKVFRHKFCLTNHHRMHTGEQPYKCNECGKAFRDCSGLTAHLLIHTGEKPYKCKECAKVFRHRLSLSNHQRFHTGEKPYRCDECGKDFTRNSNLANHHR-IHTGEKPYKCSECHKVFSHNSHLARHRQIHTGEKSYKCNECGKVFSHKLYLKKHERIHTGEKPYRCHECGKDFTRNSNLANHHRIHTGEKPYR-----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A087WQI7-1", "uniprot_id": "A0A087WQI7_MOUSE", "id": "A0A087WQI7-1", "name": "", "aln": "--------------MASCQVLLTFMDVALEFSKEEWECLDSA---QRALYRDVMLENYNNLVSVDQEAPDT----LPERTQSP-----------NP-------------------------------------------------------------------------------------------------KAHCR------------------------LSTHVT-SYKCIECGKSYTKLSSLKVHQRLHTGDKPYKCNECGKYFTKSSNLKVHHRLHTGDKPYKYNECGKFFTQVSYLKVHKRIHTGDKPYKCNECEKSFFQYSHLKIHHRLHTGDKPYKCNECGKSFTQYSDLKVHQRIHTGDKPYKCNECEKSFTRYSHLKIHHRLHTGEKPYKCNECGKSFAQYSDLKVHQRIHTGDKPYKCNDCGKSFTKSSNLKVHQRIHTGDKPCKCNDCGESYTKLSSLKVHQRLHTGDKPYKCNEYGKSFKHLSSVKIHHR-LHTGYKPYKCNECGKSFTKSSNLKVHHRLHTGDKRYKCNECGKSFTQVSYLKVHQRIHTGDKP-----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32TMX9-1", "uniprot_id": "A0AB32TMX9_DANRE", "id": "A0AB32TMX9-1", "name": "", "aln": "--------------MAFIKEESEDVEIEETFTVKQEDLQEQTGSVRTQRKTPAEATDLHTVIKMAFIKEESEDVEIEETFTVK------------------------------------------------------------------------------------------------------QEDLQEQTDLFKEYERSKEEEHHVKIEDKTHLETDDILKMRDKRCFTCNQCGKSLANKSKLKIHMRVHNREKLFTCTQCGKNFNQSSHLNQHMRIHTGEKPFTCTQCGKSFSYSANLNQHMRIHTGEKPFTCTQCGKSFSNSANLNQHMRIHTGEKPFTCTQCGKSFSQSSYLNQHMRIHTGEKPFTCSQCGKSFSQSPYLNQHMRIHTGEKPFTCSQCGKSFSQSSSLYLHMRIHTGEKPFTCTQCGKSFSKSSNLNIHMRNHTGEKPFTCLQCGKSFSQSTSLNLHMRIHTGEKPFTCTQCGKSFSQSSNPNIHMR-NHIGEKPFTCTQCEKSFSQSTSLNRQMMIHTGEKEFMCLKCENTFITAAELKRHQRVHTGEKPYKCSQCSKRFTRSGTLKTHERIHTGEKL-------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "G3X941-1", "uniprot_id": "G3X941_MOUSE", "id": "G3X941-1", "name": "", "aln": "MAQRIALDEASVPPVFCKPWAVNFADVAVYFSPEEWRYLRPA---QRALYREVMRETYGLLAYLDVGCAKPALICWVEEESEVWG---------PCAQDPEVAMCRTEVHSDCRHEK-------------------------------------------------------------------ERKRPREETEAMQKTFSPEPGQKEPQLSFAVSPSGVQATVLRADKCHDCNLCGKSFARRSTLEAHMYTHTGEKPFQCPDCNKRFGRYSSLSTHRAIHRGERPHQCPDCGKSFTQRSKLVAHMYTHTGEKPFQCPDCNKRFSRPSSLSTHRAIHRGERLHQCPDCGKSFTQRCTLVAHMYSHTGEKPFQCPDCNKRFGRYSSLSSHRAIHRGERPHQCPDCGKGFTQRCTLVDHMYSHTGEKSFNCPDCCKSFGRPSSLSRHRAIHRMEQPHRCSHCGRTFTRRSSLTSHLRVHTGEKPYCCADCGRCFSQRSAFREHQRVVHSGVTPFSCTHCGSAFADSKYLRRHMRIHTGEKPYSCPDCGRCFRQSSEIPAHRRTHTGERPYPCPQCGRQFRTKSAMTSHQWVHRPGAKGHKDKKANQLSISLDPRQEDPDPPVGF----", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *.: . * * : : : * .*.: : * : :: :* * .* * * * * * *:: . * :* . : * * *:* : : * .* * * * * * **:*. * * : * : * * ::.: * :* * : * * * ::. * .* : * * . ***:**: * . .: * * : * : * * . * : : ***:: : * .* . : : * * ***:: ", "identical_positions": 69, "similar_positions": 60, "identity": "11.02%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120709-101", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TF09-1", "uniprot_id": "DLRB2_HUMAN", "id": "Q8TF09-1", "name": "Dynein light chain roadblock-type 2", "aln": "---------------------MAEVEETLKRIQSHKGVIGTMVVN------------------------------------------------AEGIPIRTTLDNSTTVQYAGLLHHLTMKAKSTVRDIDPQNDLTFLRIRSKKHEIMVAPDKEYLLIVIQNPCE-----------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9DAJ5-1", "uniprot_id": "DLRB2_MOUSE", "id": "Q9DAJ5-1", "name": "Dynein light chain roadblock-type 2", "aln": "---------------------MTEVEETLKRIQSHKGVIGTMVVN------------------------------------------------AEGIPIRTTLDNSTTVQYAGLLHQLTMKAKSTVRDIDPQNDLTFLRIRSKKHEIMVAPDKEYLLIVIQNPCE-----------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D4A0A0-1", "uniprot_id": "D4A0A0_RAT", "id": "D4A0A0-1", "name": "Dynein light chain roadblock", "aln": "---------------------MTEVEETLKRIQSHKGVIGTMVVN------------------------------------------------AEGIPIRTTLDNSTTVQYAGLLHQLTMKAKSTVRDIDPQNDLTFLRIRSKKHEIMVAPEPM----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0AC58IU07-1", "uniprot_id": "A0AC58IU07_DANRE", "id": "A0AC58IU07-1", "name": "", "aln": "MKEYCAATRTHGGRSTPDLSDMAEVEDTLKRIQAQHGVIGTIVVNGEVSRELRWAGLRLETPGLKRNPTPALLPAFAWVSSGCSGFPYSPKTCGTGIPIRTTLDNSTSVQYAGLLHQLTMKARSAVRDIDPQNELTFLRIRSKKHEIMVAPDKEYLLIAIQNPSE-----------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VJ18-1", "uniprot_id": "Q9VJ18_DROME", "id": "Q9VJ18-1", "name": "", "aln": "-------------------MASNTVQMTFDRLVQLPGVTGAILID------------------------------------------------GNGVPVRTNLPANVARIYADRMRPLVILARSMVQDLENGDELSYVRLRTRRQETMVATENEHTIILIQDNRVLDESWRSSVASRRASAL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: *:.*: ** *::::: . *:*:**.* ..: **. :: *.: *:* *:*:: ::*:::*:*::::* ***.: ", "identical_positions": 25, "similar_positions": 37, "identity": "13.74%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120709-105", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZMG2-1", "uniprot_id": "D3ZMG2_RAT", "id": "D3ZMG2-1", "name": "", "aln": "MSREAGSCRVGTGTRARSRKPKKPHYIPRPWGKPYNYKCFQCPFTCLEKSHLYNHMKYSLCKDSLSLLLDSPDWACRRA-----PPSPRPRVPTPNCSTDFSDPSSKP-----------------------------------------TEPDLIVTNSFSQRRCGRGPKPGPEESSGSLPPLARPIRKGPGTSGLLAESWKPGLSGGMLTGALGTIASTTGSESSVPCYPPP--AQGEFPEAQSLHLSLLGVNYPLGPGLFSYLGPSLAAAAAHMPFLASASPLLPP-TAFPTPHTPERPGLAPRLYYPLLLEHNLGQSAGR----------------------------AAPAKSSVPLKGPPGALATPGLLKVPVPGPGGPWPHGTSRDAGHEGELGRVTQSNPQKRLPTGKMPE-PKAPLNLAKLGCQSSLPTGSSLILWPEDKEPVDPEASGPEVHLLQQPQGQVLGSS--VPMGEDLTQAFGDYARVEQCLGQLAPAGGLAPRPLREQLGKIRRELLTIHQALARAARPLDTPLDLSVKR-----VPTKGTEAPAESWGLHDPGPMLTRGTSEPSSMLGPVL-EPFSSRTTKCEADSSVPPPVLPLQAPEDPVIPGSGWGNRLGASSSQTPKDAPSLQILPSADVCSQPP---", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "E0CXQ2-1", "uniprot_id": "E0CXQ2_MOUSE", "id": "E0CXQ2-1", "name": "", "aln": "MSREAGSCRVGTGTRARSRKPKKPHYIPRPWGKPYNYKCFQCPFTCLEKSHLYNHMKYSLCKDSLSLLLDSPDWACRRA-----PPSPRPRVPTPNCSTDFSDPSSKP-----------------------------------------TEPDLIVTDSFSQRRSGRGPKPGPEESPGSLPPLARPIRKGPGTSGLLAESWKPGLSGGMLSGTLGTIASTPGSESSVPCYPPP--AQGEFPEAQSLHLSLLGVNYPLGPGLFSYLGPSLAAAAAHMPFLASASPLLPP-TAFPAPQTPERPGLAPRLYYPLLLEHSLGQSSGR----------------------------AAPAKSSVPLKGPPGALSAPGLLKVPVPGPGGPWPHGTSRDPGHEGELGRVTQSNPQKRLPTGNMPELPKAPLNLAKFGCQSSLPTGSSLLLWPEDKEPGDPEASGPEFHLLQHPQGQGLGST--VPVGEDLTQAFGDYARVEQCLGQLAPAGGLAPRPLREQLGKIRRELFTIHQALARAARPLDTPLDLSVKR-----VPTKGTEAPSESWRLHDPGPVLARGTSEPSSILGPVL-ESFSSRTTKCEADSSVPPPVLPLQAPEDPVIPGSGWGNRLGAGSSQTPKDTPSLQILPSADFCSQPP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0CG20-1", "uniprot_id": "PRR35_HUMAN", "id": "P0CG20-1", "name": "Proline-rich protein 35", "aln": "MSREAGSCRVGTGARARSRKPKKPHYIPRPWGKPYNYKCFQCPFTCLEKSHLYNHMKYSLCKDSLSLLLDSPDWACRRG-----STTPRPHAPTPDRPGE-SDPGRQPQGAR--------------------------------PTGAAPAPDLVVADIHS-LHCGGGPKSRAKGSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMAS-AGPEGSVPCYPPP--APGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAA-HVPFLASASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGK----------------------------AALAKAPVSPRSPSGTP-APGLLKVPVPGLG-PWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSP--EHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKR-----APAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDDPVIPGSGWGTCVATRSSQTPEAVCGLQSPQGAEV--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B9V9-1", "uniprot_id": "A0A8M2B9V9_DANRE", "id": "A0A8M2B9V9-1", "name": "", "aln": "MSKDN---CKQVGCKHKERKPKKPHYIPRPWGKPYNYKCFQCPFTCMEKSHLYNHMKYSLCKNSLSLLIES-DWPYKKDQLRLQQAAVRSRSPAKAHSEQATTPDEPSHSSANLEEEETEKRDEKDEDIQEANAENPSEACSRRAKPSKQEAELVMADMFSLEEQLLRARSVEVESKLRHYRLSKTCLSGP--AALLSEQWR-----ILSNQTSNVKPKPDVAAPSLPCYPPVSTSQIECSDPPAFNLSLLGVGYPLAPGLLSYLNPTLSNANPSNAPLPFLASQLAH-----SQRHSERSLLPPHLYYPFLCEHTFGATPSSSASEASKLIKAPSVGLQPPSYPPKLSLWKVPALRPSSSQSSPAAVWTSPTHSSPEPGLGALQERVRARDGKSSWQQETSSLKRTAMAGFDTHGAPVEKKPALEIGLETLKNTQKPASIAALMSSRMPIHNSAGSSPLHLSEQLEARQRGMERESALLQDFSALLQEYQLTEQRAASLP-----EQCHLWAHLGKIRTELSHIQQALERTARSNEGPLDLSVKKDHPLIVNAIPGETKDEDCSETEDEDDDDDDDEDDGKDRRKCSLDALMKLNPLVKTEVLTGSAEALWHSRTTKCEADS--SVLLCSKTPNRPPSIQHLDTLCPSSPLTTTDTLV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:: .* : :.****************************:***************:*****::* **. :: .: *.: *: . : : *. . .:*:::: .* . .:. * :::. .** :.**.*.*: . .. . *:***** : * .:. :::******.***.***:***.*:*: * . *. :. *. : : .:*. .*:****:* **.:* ... . * . . :....: :. . * ** * : .** . : : . . * . : .. . :*: .. * .: .. * : .. * : :*:: : :* .** ..* * :***** ** *:*** ::.*. : *******: . : :: * : . : :.: .. ::: . .. : ..* . : : :.: * *: :. ", "identical_positions": 144, "similar_positions": 162, "identity": "21.85%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120709-43", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O14649-1", "uniprot_id": "KCNK3_HUMAN", "id": "O14649-1", "name": "Potassium channel subfamily K member 3", "aln": "MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYEELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPLTLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLNLVVLRFMTMNAEDEKRDAEHRALLTRNGQAGGGGGGGSAHTTDTASSTAAAGGGGFRNVYAEVLHFQSMCSCLWYKSREKLQYSIPMIIPRDLSTSDTCVEQSHSSPGGGGRYSDTPSRRCLCSGAPRSAISSVSTGLHSLSTFRGLMKRRSSV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9D1-1", "uniprot_id": "E7F9D1_DANRE", "id": "E7F9D1-1", "name": "Potassium channel subfamily K member", "aln": "MKRQNVRTLALIICTLSYLLIGAGVFDALESKQEKSQKGRLDYRKFLLMHKYNLTRLDFDQIEKVVLLLKPHKAGVQWKFSGSFYFAITVITTIGYGHAAPSTDAGKAFCMGYALLGIPLTLVMFQSLGERINTFVRFLLHKAKKCMGLRRPEVSMANMVIIGFFSCVSTLCIGAAAFSHYEGWTFFHAFYYCFITLTTIGFGDYVALQKDNALQNDPHYVAFSFVYILMGLTVIGAFLNLVVLRFMTMNTEDERRDAEQRALLSKDKHQG---PVLRRAEPPSPSAVGRDKRRGLKSVYAEVLHFQTVCSCLWYRSREKL-----VILPQDLSFTDALMEQGDVSP---HHFFENGPTGCVCNPQRCSAISTVSADLRNISPFRLFSKRRSSV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "************:**::***:**.*******: * :: **: *: * :***:: .::::*:*** **********:*:***********************.**.*** **********************:**:***:*** :*:**.:*******:******:************** ****:*:*********************:***.:*:********** ********************:***:****:****::: : * . :.*:.. *::.*********::******:***** :*:*:*** :*: :**.. ** :: :. . *:*. ****:**:.*:.:*.** : ******", "identical_positions": 259, "similar_positions": 80, "identity": "65.74%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120709-53", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q14314-1", "uniprot_id": "FGL2_HUMAN", "id": "Q14314-1", "name": "Fibroleukin", "aln": "MKLANWYWLSSAVLATYGFLVVANNETEEIKDERAKDVCPVRLESRGKC-EEAGECPYQVSLPPLTIQLPKQFSRIEEVFKEVQNLKEIVNSLKKSCQDCKLQADDNG-------------------------DPGRNGL----------------------------------------------LLPSTGAPGEVGDNRVR------ELESEVNKLSS------ELKN--------------------AKEEINVLHG-----------------------RLEKLNL-----------------------------------VNMNN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IENYVD-----------------------------------SKVANLTFVVN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLDG-------------------------------------------------------------KCSKCPSQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EQIQSRP------------------------------------------------------------VQHLIY-----------------------------------KDCSDYYAIGKRSSETYRVTPDPKNSSFEVYCDMETMGGGWTVLQARLDGSTNFTRTWQDYKAGFGNLRREFWLGNDKIHLLTKSKEMILRIDLEDFNGVELYALYDQFYVANEFLKYRLHVGNYNGTAGDALRFNKHYNHDLKFFTTPDKDNDRYPSGNCGLYYSSGWWFDACLSANLNGKYYHQKYRGVRNGIFWGTWPGVSEAH-PGGYKSSFKEAKMMIRPKHFKP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P12804-1", "uniprot_id": "FGL2_MOUSE", "id": "P12804-1", "name": "Fibroleukin", "aln": "MRLPGWLWLSSAVLAACR-AVEEHNLTEGLEDASAQAACPARLEGSGRC-EGS-QCPFQLTLPTLTIQLPRQLGSMEEVLKEVRTLKEAVDSLKKSCQDCKLQADDHR-------------------------DPGGNG--------------------------------------------------GNGAETAE-DSRVQ------ELESQVNKLSS------ELKN--------------------AKDQIQGLQG-----------------------RLETLHL-----------------------------------VNMNN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IENYVD-----------------------------------NKVANLTVVVN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLDG-------------------------------------------------------------KCSKCPSQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EHMQSQP------------------------------------------------------------VQHLIY-----------------------------------KDCSDHYVLGRRSSGAYRVTPDHRNSSFEVYCDMETMGGGWTVLQARLDGSTNFTREWKDYKAGFGNLEREFWLGNDKIHLLTKSKEMILRIDLEDFNGLTLYALYDQFYVANEFLKYRLHIGNYNGTAGDALRFSRHYNHDLRFFTTPDRDNDRYPSGNCGLYYSSGWWFDSCLSANLNGKYYHQKYKGVRNGIFWGTWPGINQAQ-PGGYKSSFKQAKMMIRPKNFKP", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B6X4-1", "uniprot_id": "A0ACD6B6X4_DANRE", "id": "A0ACD6B6X4-1", "name": "", "aln": "--------MWFAVFYIWG-TILAFSVCDICPETSEDAASWVELKPQRHCGDEEHFCPYRLTLPPLSIQLPRPFRELEEMAKELQNLKEVVNQLRRDCQECKDRHSDRRGGWTDHSDEEERRYQSPRHNISVKNKPSPDGEKVAQIFSSTLPQGDTSESEGTIKGFEKRPNHSTLEVQEWDIKSRIDLNQGTTDPTSEMNKDVKIFNPLLEVSEDISKVPTPLGTERELKRSGLAEPSLPVKKDDVQFVTHVKQQPNVLKDGDAGNVSDILTVRRRVQNVPYQDRLRDPNIRTTDLSTSAVNKKVQNFPGGDRPLRPRGSYINSRVVKVNNEDRLKNPAVMRKTNPQVGETMGMIQPEEAGFSPARSGIMRVKETSPHIANTKSGTIRESSPLTDDQNKQDFSSVSGPKTDDKHVSQVPTVREDNSRNINITEITRLPTNLRKEKQGDVSHTDTNKSDFSIMNQAGQPNTVKEEEKHIGLSESLVIISSSAVNREDLPSPGRQVEIEKYLNPITESNNGQIGSKVLDKADRTLNAGTVNPMSPDLTDKIQPETFIVGTIEEMGFNSLNAETLKIDIPSHSEATFSEDLVKPTIVPAVKSKSRNGNVRMTSRFKPPVGGHGARRSSITPLKAVPEQPQNGKKNISMTHEVRQELKYVMPRLLSNSDTTVISPTGPKLRPNITSKTSANRSVGEPSKLPIPVRNGHVPRKNVSGILKPIYTRRKPNFQTEMNTNRGIKTKVSTRNQFFSPTGATPTVRRGEIKHIPQVITSNVLDNQQSTNNITEPKSQPESQNPGDIRDLDKVQEAMNRPGDNSEIVLISNNENRSQDPNTMQRGTSNSPAGEKEGKIFSLGGASISGQNPSEEDKIRSGRKRPTTSTLKKELPKEPGASQFITSNVSFTDMEHGDSMKNIHTVTNTHVEKSNNPSQDTPRSFENTGPAPNVRSTVLHNLWIKNNNTESKSPPISQNAANVQDLDQVQQGKTHVRDNSEVVLILNTENSEEDPNIQQSGGSNVPTSGTERKTFSLGTADKLERGKKGTNTPTLKKKELFKDPGTTQFINSTVSFTDMQHRDSTKNTGSVTNAHVEMPKNVSRDTPISFESIGATKELEHIKLNKDRVDEIPEDVLSNPNTVDTANGYSGEKYAIPVVLETLTNTEEIKGSKVFSLSPEDTAEGFKSHAVSDEVTEREKAENKIHSTCLGNCNTTSTPHSQPSTSQTRTPLAPEREKRPAQDCADYITKSRRN-GVYRVTPRPKNTTFPVFCDMASSGGGWTLIQHRFDGSTSFNRTWDEYKNGFGKLIGEFWLGNDKIHLLTKAKNMSLRIEIEDFEGIREYAQYDHFYIANESQQYRLSIDGYSGTAGNAMQFSKKYNHDQKFFTTPDRDNDQYPSGNCGAYYSSGWWFDACMSANLNGKYYQSKYKGVRNGIFWGTWHNITMEYYPTNERQSFRTVRMMIRPTNYAN", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **: : . : : . .. ..*: :* : **::::**.*:****: : :**: **::.*** *:.*::.**:** : .*. .*. :* .. :. *: *:..::.*:.: ***. .*:: : *:. **. :: *::** **:*:: .*: *.:*. *:.* : *: *** *.: *.* .:: *: :**:*: . .:*. .***** :*::* *:*** : *****::* *:****.*.* *.:** ***:* **************:*:* ***::***:*: ** **:**:*** :*** :..*.****:*::*.::**** :******:***:******* *********:*:*********:.**:*********** .:. * . :.**: .:*****.:: ", "identical_positions": 195, "similar_positions": 144, "identity": "13.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120709-59", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2LKU9-1", "uniprot_id": "NLR1A_MOUSE", "id": "Q2LKU9-1", "name": "NACHT, LRR and PYD domains-containing protein 1a", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MEESQSKQESSTKVAQH------------------EGQEDVDPTFKTKKLMEVELMKHRVQLER----------------NLKLRTFPGARTKQVKEALYPLLTWSSKSKNLFQNFTKLLLFKKLCQRGSENLVRESWYPCVP-----EEEAHMIDIQDLFGPNLGTQKKPQLVIIEGAAGIGKSTLARLVKRAWKEGKLYRNDFHHVFFFSCRELAQY-EQLSLAELIVQGQEVPTAPIRQILSH-PEKLLFILDGIDEPAWVLADQNPELCLHWSQTQPVHTLLGSLLGKSILPGASFLLTTRTTALQKFIPSLEQP-CQVEVLGFTLFERKNYFYKYFGKKKGGVTTFTLVKSNSALLTLCEVPWVCWLVCTCLKKQMEQGGELSLTSQTTTALCLKYLSLTIPGQHMR-TQLRDLCSLAAEGVCQRRTLFSESDLCKQGLDEHAIASFLKIGVLQKQASSLSYSFAHLCLQEFFAAMSYILDDSEE---RHADMKNDRIVETLVER-----YGRQNLFEAPTVRFLFGLLSKEE----LKKIEKLFS--CSLHGKTKLKLLWHILGKSQPHQPPCLGLLHCLYENQDMELLTHVMHDLQGTIVPGPDDLAHTVLQTNVKHLVIQ------------TDMDLMVVTFCIKFCCHVRSLQLNRKVQQGHKFTAPGMVLYRWTPITDASWKIFFSNLKLARNLEELDLSGNPLSYYAVHSLCTTLR---------------------------------------------------------KRGCQLKTLWLVECGLTSTYCSLLASVLS-ARSSLTELDLQLNDLGDGGVKMLCEGLRNP----ACNLSILWLDQASLSDQVIAELRTLEAKNPKLLISSTWKPHVMVPTMNMDKEEVGDSQALLKQQRQQS------------------------------------------------GDKHMEPLGTEDEFWGPTGPVTTEVVDRERNLYRVQLPMAGSYHCPSTGLHFVVTRAVTIEIEFCAWSQYLDKTPLQQSHMVVGPLFDIKAEQGAVTAVYLPHFVALQEGI-VDSSLFHVAHFQEHGMVLETPARVEQHYAVLENPSFSPMGILLRMIPAVGHFIPITSTTLIYYHLYLEDVTFHLYLVPNDCSIRKAIDDEEMKFQFVRINKPPPVDALYLGSRYIVSSSK--LVEIIPKELELCYRSPGESQLFSEIDIGHMDSEIKLQIKDK-RHMNLKWEALLKPGDLRPALPKIATA-------PKDAPSLLHFMDQHREQLVARVTSVDPLLDKLHGLVLSEDSY--EVVRSETTNQDKMRKLFSLSRSWSWDCKDQFYQALKETHPHLVMDILEK---LGGVSVKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A1Z198-1", "uniprot_id": "NL1B2_MOUSE", "id": "A1Z198-1", "name": "NACHT, LRR and PYD domains-containing protein 1b allele 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MEESQYKQEHNKKVAQD------------------EGQEDKDTIFETIEAIEAKLMELKTNPES----------------TFNYGIFPEVYMNQGEEILYP--AWSLKEENLFQTFKSLRLFQKLCPRGSGNLVKKSWYPCVP-----EEGGHIINIQDLFGPNIGTQKEPQLVIIEGAAGIGKSTLARQVKRAWMEGELYRDHFQHVFFFSCRELAQC-KKLSLAELITQGQDVPTAPINQILSH-PEKLLFILDGIDEPAWVLADQNPELCLYWSQTQPVHTLLGSLLGKSILPEASFLLTTRTTALQKFIPSLPQS-CQVEVLGFSDFEQEIYIYKYFAKQIFGIKALMMVESNPVLLTLCEVPWVCWLVCNCLKKQMEQGGDVSLTSQTTTAICLKYISLTIPVHHMR-TQLRALCSLAAEGIWKRRTLFSESDLCKQGLDEDAVAIFLKTGVLQKQASSLSYSFAHLCLQEFFASMSCILEDSEE---RHGDMEMDRIVETLVER-----YGRQNLFEAPTVRFLFGLLSKEG----LKEMEKLFS--CSLPGKTKLKLLWHILGKSQPHQPPCLGLLHCLYENQDMKLLTHVMHDLQGTIVPDTDDITHTVLQTNVKHLVVR------------TDMELMVVTFCIQFCSHMRSLQLNMEGQQGYALTAPRMVLYRWTPITNASWKILFYNLKFNSNLEGLDLSGNPLSYSAVQYLCDAMI---------------------------------------------------------YPGCQLKTLWLVECGLTPTYCSLLASVLS-ACSSLRELDLQLNDLCDDGVRMLCEGLRNR----ACNLRILRLDLYSLSAQVITELRTLEENNLKLHISSIWMPQMMVPTENMDEEDILTS---FKQQRQQS------------------------------------------------GANPMEILGTEEDFWGPIGPVATEVVYRERNLYRVQLPMAGSYHCPSTRLHFVVTRAVTIEIEFCAWSQFLDKTPLQQSHMVVGPLFDIKAEQGAVTAVYLPHFVSLKDTK-ASTFDFKVAHFQEHGMVLETPDRVKPGYTVLKNPSFSPMGVVLRIIPAARHFIPITSITLIYYRVNQEEVTLHLYLVPNDCTIQKAIDDEEMKFQFVRINKPPPVDNLFIGSRYIVSGSE--NLEITPKELELCYRSSKEFQLFSEIYVGNMGSEIKLQIKNK-KHMKLIWEALLKPGDLRPALPRIAQA-------LKDAPSLLHFMDQHREQLVARVTSVDPLLDKLHGLVLNEESY--EAVRAENTNQDKMRKLFNLSRSWSRACKDLFYQALKETHPHLVMDLLEK---SGGVSLGS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "M0R4T2-1", "uniprot_id": "M0R4T2_RAT", "id": "M0R4T2-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------MEESQSKEESNTEGAQHAV---------------EEGTGDLCPNFQTEIDLEMFLKKRIEMLQEK--------------PQRKFRLTLSEMMKQKGENIHS--TQPLKRENVFRNFTNLLLFRKFCPRDSEKLVRKSWHSCVP-----EEGGHMIEIQDLFDPNSDTEKRPQLVIVEGAAGIGKSTLARQVRRAWKEGQLYRDRFQHVFFFSCRELAQC-KQLSLAELIAQGQEVPTAPIRQILSR-PKKLLFILDGIDEPAWVLEDQNPELCVHWSQAQPVHTLLGSLLGKSILPEASLMLTARTTALQKIIPSLGQP-NQVQVLGFTEVERENYFYRYFAKQRVAMTAHMKLQSNPVLQTLCEVPWVCWLVCACLEKQMQQGEVLSLTSQTTTALCLKYLSLTIPGQHLS-TQLRTLCSLAAEGICQRRTLFSKSDLCKQGLARNAINTFLEIGVLQRQPSSLSYSFAHLCLQEFFAAMSYILEDSEE---RHGDMGNDRTVETLVER-----YGRQNLFEAPTVRFLFGLLSEEG----LKEMEKFFS--CNLLRKTKLELLWHILAKFQSHQPHSLGFLRCLYENQETQLLSHVMHDLQGIIVPDTNDRAHSVIQTNVKHLVIQ------------TDMELMVVTFCIQFCYHVRSLQVNMERQQGYELTAPRMVLHRWTPITDASWKILFSNLKFTRNLEELDLSGNPLSYSAVCSLCKALK---------------------------------------------------------QPDCQLKSLWLVECGLTSRCCSLLAEVLS-AHSRLTELDLQVNDLGDNGVRLLCKGLRSP----ACNLSILRLDQASLSDQVIMELRDLEAKNPKLRISSTWMPHMMVPTENMDGEDIMDS---FKQQRQQS------------------------------------------------RETLMETLGTEDDFWGPSGPVSTEVVDRERNLYRVQLPMAGVYHCPSTGLHFVVTRAVTIQIEFCAWSQFLDKTPLQHRYMVAGPLFDIKAEQGAVTAVYLPHFVSIQDPK-ASTFDFKVAHFQEHGAVLETPVRVKHRYAALKNPSFSPLGVVLRIIPAARRFIPITSITLIYYHLSLEEVTLHLYLIPNDCTIQKAIDEEEKKFQFVRIHKPPPVDSLYIGSRYIVSGSE--KLEITPKELELCYRSSKEFQLFSEIYVGHMGSEIKLQIKDK-KHTQLIWEALLKPGDLRPALPRIAPA-------TKDAPALLHFMDQHREQLVARVTSVDPLLDKLHSLVLSEDSY--EAVRAETTNQDKMRKLLSLSRAWSRAGKDQFYNALKETHPHLVMDLLEM---SGGVSLRY", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9C000-1", "uniprot_id": "NLRP1_HUMAN", "id": "Q9C000-1", "name": "NACHT, LRR and PYD domains-containing protein 1", "aln": "MAGGAWGRLACYLEFLKKEELKEFQLLLANKAHSRSSSGETPAQPEKTSGMEVASYLVAQYGEQRAWDLALHTWEQMGLRSLCAQAQEGAGHSPSFPYSPSEPHLGSPSQPTSTAVLMPWIHELPAGCTQGSERRVLRQLPDTSGRRWREISASLLYQALPSSPDHESPSQESPNAPTSTAVLGSWGSPPQPSLAPREQEAPGTQWPLDETSGIYYTEIREREREKSEKGRPPWAAVVGTPPQAHTSLQPHHHPWEPSVRESLCS--TWPWKNEDFNQKFTQLLLLQRPHPRSQDPLVKRSWPDYVE-----ENRGHLIEIRDLFGPGLDTQ-EPRIVILQGAAGIGKSTLARQVKEAWGRGQLYGDRFQHVFYFSCRELAQS-KVVSLAELIGKDGTATPAPIRQILSR-PERLLFILDGVDEPGWVLQEPSSELCLHWSQPQPADALLGSLLGKTILPEASFLITARTTALQNLIPSLEQA-RWVEVLGFSESSRKEYFYRYFTDERQAIRAFRLVKSNKELWALCLVPWVSWLACTCLMQQMKRKEKLTLTSKTTTTLCLHYLAQALQAQPLG-PQLRDLCSLAAEGIWQKKTLFSPDDLRKHGLDGAIISTFLKMGILQEHPIPLSYSFIHLCFQEFFAAMSYVLEDEKG---RGKHSNCIIDLEKTLEA-----YGIHGLFGASTTRFLLGLLSDEG----EREMENIFH--CRLS--QGRNLMQWVPSLQLLLQPHSLESLHCLYETRNKTFLTQVMAHFE------------------EMGMCVE------------TDMELLVCTFCIKFSRHVKKLQLIEGRQHRSTWSPTMVVLFRWVPVTDAYWQILFSVLKVTRNLKELDLSGNSLSHSAVKSLCKTLRRPRCLLETLRLAGCGLTAEDCKDLAFGLRANQTLTELDLSFNVLTDAGAKHLCQRLRQPSCKLQRLQLVSCGLTSDCCQDLASVLS-ASPSLKELDLQQNNLDDVGVRLLCEGLRHP----ACKLIRLGLDQTTLSDEMRQELRALEQEKPQLLIFSRRKPSVMTPTEGLDTGEMSNSTSSLKRQRLGSERAASHVAQANLKLLDVSKIFPIAEIAEESSPEVVPVELLCVPSPASQGDLHTKPLGTDDDFWGPTGPVATEVVDKEKNLYRVHFPVAGSYRWPNTGLCFVMREAVTVEIEFCVWDQFLGEINPQHSWMVAGPLLDIKAEPGAVEAVHLPHFVALQGGH-VDTSLFQMAHFKEEGMLLEKPARVELHHIVLENPSFSPLGVLLKMIHNALRFIPVTSVVLLYHRVHPEEVTFHLYLIPSDCSIRKAIDDLEMKFQFVRIHKPPPLTPLYMGCRYTVSGSGSGMLEILPKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDK-KDETLVWEALVKPGDLMPATTLIPPAR-IAVPSPLDAPQLLHFVDQYREQLIARVTSVEVVLDKLHGQVLSQEQY--ERVLAENTRPSQMRKLFSLSQSWDRKCKDGLYQALKETHPHLIMELWEKGSKKGLLPLSS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A386CAB9-1", "uniprot_id": "NLRP1_DANRE", "id": "A0A386CAB9-1", "name": "NACHT, LRR and PYD domains-containing protein 1 homolog", "aln": "----------------------------MSSDYTDRNNLASAIKTLGDMLEKDEAFQRLMYNASTKGEINRGRVNKVFLKALLSAGDKVG------------EFLNELIDHLNLFKVLGDFSWNPPVLKEAELNERTSQLRTQQHKYVERVSGFSHYG----FGETGTPARGDITSPRGPQ------------------VASIEEDLATSKLAELLLAVGDHLEKIEK----------------KGQFLPENVERFSLDCFITSESVKLSSEAVELAPCYTEPVIIQRSKEQTEKYCQEYVRSPHTSSHLLSNDKTQSIRIGQLFSPDSDGN-TPKTVILCGDSGRGKSFVLEKIILDWVHLEHHFENFDAVFLLKYEELKCLSEEMSLTELLSRSCSLTSDQISQILQLTPEKVLFLIDGIDDFSFNAHIQIS-SPTDPSQKAPVISIIHCLMRDLLLVESSVIVTTRYTAAAELSSLCKRPQRFTEIEGFSERRVQEYFQKFFQDEQLFKKAYESMKTNETLLTFCSVPLLCWMVCFCLKKDADQ---VMTELKTTTSIYVHFVSTLLEDHHQSQSFLRSLGQLAEEGMKNRQNLFDEKSVTRTGLDPATRVFMNKIYLKRKKKHELLFKFKHLSFQEFFAALYYIMLDEEESWCKVSELFNMMESEALIHRSPPIFRGRLSNPIPSVMMFLCGLFNKKVSSSLFEKMKSTFSHNVKLKKKELKKKLMKMIPAMIRQYGFELFALHCLYELQDERFVTKVLETHKFIDLSNVSLRSTDCLVLCYCLRLCPNIRELNFMNCDLTAAKLKILQPALGLCETLRFSVEHLSEIGDLIQILSESKILRELKVREDEYGVESPRWSFNLSVTRGDVLLTLSSSEKNPSFSSVLN--------------------------------------------------------IRLTCAQSQISRTDWTLFLQRLRKTGTLTEDSSADDDHVSLQLSSLHSVGLKSLDLTLVSLNESWASGIISLIQNCTSLQQLKVSVTGLLLEEGLKLLKKSLTDPHCTVIIEGRRNCSEPSEEHLRQSYEKVEIHFKPKLLEELAELSICN--------------------------PGSSALNIHCQSCVDVADSDQWVQVEPSVCRGEGGTEFRITTPAGRFQCSRTRMRWVCDGDVTLHYRAVDG-HFLNAELERLQCERVAPVLDVNVISGKLEEAHLPHYMCLAESDPALTNAVKLLSVEDEGISLES-VELTRFHAKILQPMFSPKTVLVKLG-----IPVKVHCDLLIFMTHTCPIILNVYFFPSDSLVEENIKTEEKSSHQIKCSRPE--APLQMKKQHSLEVPD---AVVQPEAIKLRGNMKPNFFQVKQPVVNDITMILSRVDDQKSVWTGTIWKKLIDIKLNKTESDLFQSGQKHKTSQPAHSFDKAQFFDTHWCNLIKSVENVDTVADKLLQKQIIHEQFYSEIIHHKSTSEESMRKICVIVRKGSAAVKEIFISILLQENPNLLNHLPSS---------DS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : . . . . .. : . . . . : :. :.. :::: : . . . :: : * * :**.*. . : *: **: * :* *** : . : * . : : : *. ** :. .** : :**:**: :. .. * ***. *:::**::**:*: .: . ** *. ::: .*: . :* :*.::*:* ** :: . :. .:: **: : *: ::* .: : :::* * ::* ** :.*:.* ** :: .: : :***:: ::::: : : . ** * .** **: :::.**. ..: : ** : : : :.: * :.* **.:*****:: :: *.: : . * :. * . ... ** **:..: .:::. * * : : : * *:**** :: ::::*: : * .* : .: :. :: . : * : : : : .. .: *: . * :. .: * . : .. * . : . : . .:.** ..* . *:: * * *. : * : :*. * : :* * * . . . . : . . .: . * ..* * . . ** :: . * : :* **:. . ::*. : ..*::*::. * : .:***::.: . : .:: .::.* **. .: : : :* *** ::::: : . *: . : :::*:.*.*. :.: *. * . : :: :* * : :: :. . : *: ::* . : ..: :..: : .:* *: *:. . : . .: :*.* : :*: * .*: : *** : .:.: * : :.* ..***: : : . *: : . * : :*:*: .: . ", "identical_positions": 168, "similar_positions": 369, "identity": "10.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120709-60", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1Z7N0-1", "uniprot_id": "A1Z7N0_DROME", "id": "A1Z7N0-1", "name": "Leucine-rich repeat-containing protein 34", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MCDVLLPCEY----------------NPKECPSPAAEKSRLFTILLLYCWQR----------------------EYDKRPYRQFQFKRLTFEERIGRRYHCIRDLRIIVNYLLRRPQLSVQISSLVVSNWDAGLLKDFVRSLLPVWYIELRLMRFPR------------EFFVMLRLNAAKMNVSQLSLEGTPLTDEDVR--------------------------------------------ILREFLLVSKT----LRRLNVSSCSLTQFNFALIADGVYKSPGVRRLSANRLLGMSLS-------------------------------------------------------------------------LDTEKISSVLSSLLMQN--------------------------------------------------TLWALSLEHCELTAQDMIPIAEHLARTNSKFRRLRIA-CNKIGPDGAFFLLRGMSMGGNLELLDLSY----------------------------CSIGTHGGEWVAKYLASCRRLQVLHLNYNDMGPTAVNLILL-AMKKQCKLEKLTLYGNHFDSRTAMIVRRLLDAEVVLHSELDISYTY------------------------------------------------------------------DEALQDYRVVPWR---------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "A0A8M1RJ47-1", "uniprot_id": "A0A8M1RJ47_DANRE", "id": "A0A8M1RJ47-1", "name": "", "aln": "MMSAEKSDDAPATGSSPEDLQAEQHEQKKSDSSTVSHVSMKSGRSITPPLDFRKDEQGNTERAKQERAESSTASHLSMKSDRSITPPLDFISGEQKQTERKSVDDHAVSTSADRVCQRHHRALDVFCQTDNIHICCICVEEEHQGHRKTYTAKLNVPDSQSMLLHIMEKMRSEDFNTFKRELSEDYAGCLGAQSEELSVSEAAENIMRSFGGEAALRLILHFQTKANPLKKITDANKTKLKNKCQNINEGNSSYGKQSLLMEVYTDLYFTEGGSGEINNEHEVLRNEMISQSRTTQEVLYACDEIFKTLPGQRTQVRTVLTMGIAGIGKHVSVQKFILDWAEGKANQDIEIIIHLPFRDLSCREESCSLLQLVHQYSPELREADLQHLKVLFILDGLELCQYPLHFHKNVYCADINEKVPVDALLTNLIKGNLLPSALLWITTRPSTAGRIPPECVHRVTEIRGFSDDQKDSYFRKKISDQTLADEIIRHIKSCQSLYIMCHMPIFCWISATVLENIMREGQSEELPRTLTGMFTHFLLLQVSLKHKKFNGADGDNPKKLSEFDQTFILKLGELAFQQMEKGDLIFREEDLREGGIDVSKVSEYSVCTEFFREELGLYREKLYGFLHVSYQEFLAAIYAHFTCVNDGRNVFLKDESRSSVDLCDVHQTAVEKALQSENGHLDLFLRFLLGLSVDSNFNLLQDLLKDTSCKPRVDTSSTVSFIKEKVKLEQSPERIINLFHCLNQLNDNSLVEEIKAAMKSGTLLGSELDPEQWSALAYVYLTSGEEIEEFDMIKSNQLRLLPVLRICKKARLNCCNLSFASCGLVASALKSVNSPLTELDLSNCKLNIFGMNTLLDGLKSPHSKVKKLRLAGCFFPSETCANLALALKSVNSQVTELDLSYNKITDGVHKFCAGLTSQNCKLQKLVLKRCGLTKASCAHLASVLKSNTHLMELELKGNDLQDSGVELLSTGLMDPQCRLEKLGLSGCMITKVGCNSLASALTSNADCMSELDLTYNHPGDSGVKLLTAKKEDPNCKLEKLHVKKRGECRMKPGLRKYACQLTVDPNTIHPRLIVSNDNRTISETTEHQKYPVHPDRYTLYPQAMCREPLADRSYFEVKCTGGVSIGVAYKTSDRTEDLMGFNNTFPSLMCLNGRIKLWQNNDVIHYELPVFAQSSRVGVYVDQYQGSLSYYSICKDTLIHLHTHHTEFTSPLYIGFLFMPDSSVTLLDDSL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * *:* * :. . *..*:. **: * : :* .* : ::. *: :.* *: :. :.* *: : : :. :..:: .. . * : :. : . ::: * : ** : *: .:: ..*:. . : :**:* * .* *.. *: . ** .* :.: : : ..: .. * * . ***:*:. **.*: *:: * .. .* *.*.:*:*. .* .: : * .:**.::**:* * . * : * *:..:: ***** *.: . . :*. * * :* *.*: **: :.*:*: *. **:**** * * : . . : * ::. ****::*.: *.* * * * ", "identical_positions": 96, "similar_positions": 137, "identity": "7.8%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120709-81", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q61038-1", "uniprot_id": "GPR65_MOUSE", "id": "Q61038-1", "name": "G protein-coupled receptor 65", "aln": "------------MAMNSMCIEEQHHLEHYLFPVVYIIVFIVSVPANIGSLCVSFLQAKKENELGIYLFSLSLSDLLYALTLPLWINYTWNKDNWTFSPTLCKGSVFFTYMNFYSSTAFLTCIALDRYLAVVYPLKFSFLRTRRFAFITSLSIWILESFFNSMLLWKDETSVEYCDSDKSNFTLCYDKYPLEKWQINLNLFRTCMGYAIPLITIMICNHKVYRAVRHNQATENSEKRRIIKLLASITLTFVLCFTPFHVMVLIRCVLERDMNVNDKS--GWQTFTVYRVTVALTSLNCVADPILYCFVTETGRADMWNILKLCTRKHNRHQGQKRDILSVSTRDAVELEIID---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IYL9-1", "uniprot_id": "GPR65_HUMAN", "id": "Q8IYL9-1", "name": "G protein-coupled receptor 65", "aln": "--------------MNSTCIEEQHDLDHYLFPIVYIFVIIVSIPANIGSLCVSFLQAKKESELGIYLFSLSLSDLLYALTLPLWIDYTWNKDNWTFSPALCKGSAFLMYMNFYSSTAFLTCIAVDRYLAVVYPLKFFFLRTRRFALMVSLSIWILETIFNAVMLWEDETVVEYCDAEKSNFTLCYDKYPLEKWQINLNLFRTCTGYAIPLVTILICNRKVYQAVRHNKATENKEKKRIIKLLVSITVTFVLCFTPFHVMLLIRCILEHAVNFEDHSNSGKRTYTMYRITVALTSLNCVADPILYCFVTETGRYDMWNILKFCTGRCNTSQRQRKRILSVSTKDTMELEVLE---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A956-1", "uniprot_id": "A0AB13A956_DANRE", "id": "A0AB13A956-1", "name": "", "aln": "MNVTDSWISFSTQSNESKDCYPPAHPERKIFVALHLTVILIGIPSNIFFLFVSYRLIRQKNELGVYLFNLALSDLLFITCLPVWIEFALN-DQWLHGEAACTVCVFLLFTYFYTSIVLLSCIAVDRYLAIVHPLKFSTFRKRRIALSLSVAAWIFALVFN-------AITVDLNGVYDEENKVCLDVY-LSHKQKWANVTRFVVGFLIPALVVGFCYWRICSDIKNNQTLRSMELQHVFKLLVCVLLTLYLCFGPVHIMMVLKVLLESCPHP-------SWLFFAYKTSVFLATLNCLADPLLYGFTSRTGKDSASGMLLILRRAWRKETQTETVQHNEHINGTAMLSNDKSPI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . :: :* ::: *:::.:*:** * **: :::.***:***.*:*****: **:**::: * *:* .. : *. ..*: : **:* .:*:***:*****:*:**** :*.**:*: *:: **: .** *: . ..: .:* * * *.: * *: * *: ** :.: :* :: :::*:: .. * ::::***..: :*: *** *.*:*:::: :** : : *: :* *::***:***:** *.:.**: . .:* : . . . ..: *. . ", "identical_positions": 98, "similar_positions": 115, "identity": "27.68%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120709-85", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3USH1-1", "uniprot_id": "INSY2_MOUSE", "id": "Q3USH1-1", "name": "Inhibitory synaptic factor 2A", "aln": "MVSKDSGRCILTTPEREVEPAACLALEMRYALDPNRQIKKRNKALQVRFKDICEAQNEQRDTQLSSGPLGEKREAKAVSCRVAYRKYMTVPARRSIPNVTKSTGVQTSPDLRKCYQTFPLDRKKG-SLKGLPAADAFKSQNNGFLADSKEKSEAGPMEEPRPCSAGRIHKTTALVFHSNEHVNALGQPSGVNCAELCKSPDVLGYPEAVLQNS-RPPSEEPIHQLQGRAKLDRGT-LDSEEPAPLTHGRVFKTEVATVYPPAISTRAPEPGLSNSAAASQWSLCPADEEQRRAAHLNGLQASTGSA--VACSTPVQYLSPECSEQP--------LQNQPSPTAGIGDEEHQQIVPHTEVVDLKAQLQVMENLISSSQETIKVLLGVIQELEKGEAHREGLSYRTGQDTANCDTCRNSACIIY-----------------RYVN-----ILFPLCYSE--------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZSG2-1", "uniprot_id": "INSY2_HUMAN", "id": "Q6ZSG2-1", "name": "Inhibitory synaptic factor 2A", "aln": "MVSKDTGKCILTTSESEVEPAACLALEMKYALDPNRQIKKRNKALQVRFKDICEAQNEQRDTQLSSGQLGEKREAKPVSCRAAYRKYMTVPARRSIPNVTKSTGVQTSPDLKKCYQTFPLDRKKG-NLKSLPAADPFKSQNNGFLTDAKEKNEAGPMEEARPCGAGRVHKTTALVFHSNQHMNTVDQPLGVNCTEPCKSPEPLSYGEAALQNSTRPPSEEPDYQLLGRAKQDRGR-PNSEEPAPPALRRVFKTEVATVYAPALSARAPEPGLSDSAAASQWSLCPADDERRRATHLNGLQAPSETA--LACSPPMQCLSPECSEQPSQTHTPPGLGNQPSPTAVAAGEECQRIVPHTEVVDLKAQLQMMENLISSSQETIKVLLGVIQELEKGEAHREGLSYRTGQDTANCDTCRNSACIIYSVELDFKQQEDKLQPVLRKLHPIEETQVIPSPYSQETYSSTPKQKSKTESKKHGRWKLWFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A286Y931-1", "uniprot_id": "A0A286Y931_DANRE", "id": "A0A286Y931-1", "name": "", "aln": "MVSKEAGRCTLSSSESDSE-SGGPSLER----SGADAVRKRNKALQVRFKDICEAQNEVAHRGARD---------RSVSCKVIHRRYMTMPARRSIPNVTKSTGVQTSPDLKKRYQTFPFERKKGNVIKHTALVENHPDQNNGFLSDVKDGKRG-----AR--CDGHVQQTRVLLHTTPQCSDAKDLCAGPDCSDGKLCPD-LSDAALDQSDANVPGSGAKHKGLPSESEAGVGQQPNCASSTTPTQPLPVRGDCSKISGPIAWTSLTQVECPESPSGS----CAR---KKDTAQLNGLQTQSQALPHSASCASQAHIRAHCHSSQ---------NSGPTETQQQGTRGQLIALPGVDG-NVKARLQAMETLISSSQETIKVLLGVIQELERGEAQREGLSYRTGQDTANCDTCRNSACIIYSVELDFKLQEDKLQPLMKRLCPLEEPLYPSLPYAHEVFTSTPKRKSKTESKKHARWKLWFL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****::*:* *::.* : * :. :** . ::******************* . . :.***:. :*:***:*********************:* *****::**** :* . .: . .******:* *: ... .* *::::* .*:. : : :: . * :*:: .*: *. .:: * * * ..:: . * :. ..:. : .: : :.: * : .: .:*.:.* *. :: :::*****: : : *.... : ..* .. . *: * . . :* .: ::**:** **.********************:***:************************** : : . *:. ", "identical_positions": 159, "similar_positions": 120, "identity": "32.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120709-88", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8Z4-1", "uniprot_id": "D3Z8Z4_RAT", "id": "D3Z8Z4-1", "name": "", "aln": "MRSDPALMASFLLLLPLVLPGQPQLVRSVLSSMDESGTFQCVVHLPNSSIFLQQLEQLQSTLQELIGKYEQELSRVKEYAHVIEDQDSQTLELSHMLEARNPGVTLSQYDNPAFNLLRLELEGAQELAAQLKANGGVSGASDLLYELQNRVTNASLTLKLLVDSDRQSFHALQEEVDILEGQLSECEREKEQEQSSRHPGPPLAPGSCAHGGLQKVSRPLVVKLNWRGLSYKAGAWGRDSAPNP-VSSLYWVAPLRADGRYFDYYRLHKSYDDLVL-LKHYEQWKMGYG------DGSGNTVYKNFMYFNYYGTRYMAKVDLSSNTLVLRRPLPGATYNNRFSYACVP----WTDIDFAGDEKGLWVFYATEESKGNLVVSLLNDST-LEVEQTWYTSQYKPALSGAFMACGVLYALRSLSTRQEEIFYAYDTTTG-QEHHLSILLDKMLETLHGINYCPWDHRLYVYNDGFLINYDLTFLTLKLPSSPMKRPSGAPAPFKPIKSNQPSRIRDSMTHQGPIRNMFSPSPLEGRFP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M6YVZ3-1", "uniprot_id": "A0A8M6YVZ3_DANRE", "id": "A0A8M6YVZ3-1", "name": "", "aln": "------MSPNQIFILLIIIP--PAFFQSARGKD-------CVCDLKNSEPAFPDHKLTKVEATAKQCIRTITSEKMMEMDILVLGLQQRITQLDENMAKLENEDNSKLYGAVSMRIIDLEIAEIQNLLDKLNAT--TKGYNHLSIQTADQLEDMKDTMEDLEKFDNMQVVKKDRENQRYKKQLEECKDELEAT----LPPPTVLPGRCGLGRLVKVAGPRTYSLTVYSTSYTYGAWGRDVNPAPGDENKYWLVVLYTSNVYGNFIRQYSTLSTFLLNIGPIDTYIAGSNPTTNTIQGPNMVMYANALYYNCYNSYSVCQFNMTTKSVNTVALPSDTGYSSKFPFAHLGHTYGYTDMDFVTEESGVYVIYATTSNFGNVVISKVETSTPPVLGQTWSTSLHKRTVTNTFMVCGVLYATRYLDKETEEIFYSYDTKTNKERYDLRIHIKKMQANIQFLNYDPRDHLLYAYSDAYIVTYELVFQ------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .. :::* :::* * :.:*. .. ** .* **. : : : : .:: * :: . :.: :*.. : : . . *. ::.:: **: *:* :*:*. ..* ..* : ::: : . *:: * . *. .. :.* : : **.**: * * * *.: ** *. * * **: * . .*. . **. ****** * * .. **:. * :.. * :: * :.: . ::* : : : * . :*.. .:* * :*:* *.: :.:.::::::: ..: *..:*.:* : :**:**. :*.*::*:*** .. **:*:* :: ** : *** ** :* :::.:**.****** * *... *****:***.*. :.:.* * :.** .:: :** * ** **.*.*.:::.*:*.* ", "identical_positions": 124, "similar_positions": 174, "identity": "23.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120709-89", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BVV7-1", "uniprot_id": "TIM21_HUMAN", "id": "Q9BVV7-1", "name": "Mitochondrial import inner membrane translocase subunit Tim21", "aln": "MICTFLRAVQYTEKLHRSSAKRLLLPYIVLNKACLKTEPSLRCGLQYQKKTLRPRCILGVTQKTIWTQGPSPRKAKEDGSKQVSVHRSQRGGTAVPTSQKVKEAGRDFTYLIVVLFGISITGGLFYTIFKELFSSSSPSKIYGRALEKCRSHPEVIGVFGESVKGYGEVTRRGRRQHVRFTEYVKDGLKHTCVKFYIEGSEPGKQGTVYAQVKENPGSGEYDFRYIFVEIESYPRRTIIIEDNRSQDD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CCM6-2", "uniprot_id": "TIM21_MOUSE", "id": "Q8CCM6-2", "name": "Mitochondrial import inner membrane translocase subunit Tim21", "aln": "MICAFLRVVQHAEKLHG-SLGRQLLPHFVFTKACFKTQP-LRWGLREQKITVQPRTVLRFTQKTFWTQGPDPRKAKEDSTKQVSIRRNQREETGVSMSQKVREAGRDVSYLIVVLFGVGLTGGLLYAIFKELFFSSSPNIIYGKALGKCRTHPEVIGVFGEPLKGYGEMSRRGRRQHVRFSEYVNNGLKRIRVKFYIEGSEPGKQGTVHAEVEENPGSGQFEFRYIFVEVT--PTRSIIVEDNRSEQS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F4T6-1", "uniprot_id": "E7F4T6_DANRE", "id": "E7F4T6-1", "name": "Mitochondrial import inner membrane translocase subunit Tim21", "aln": "MSSLVLRIGRTTNCVQH-ILKRVHVRLQQPRSSLLTLDP-----VFQTNHCPCSKWAFYHTRSLYTGVYLCSRKDEQKDTDQLSVSRSPHTPSRGSATQKVKQAGKDFTYLIVVLIGLGVTGGLLYVVFQELFSSSSPSKIYGKAFERCRSHPEVIGAFGEPIKGFGETSRRGRRQQVSHLEYMKDGLKYMRLKFYIEGSEPGLRGTVHSESKENPETGKYEFRYIFVEIDTYPRRTIVIEDNR----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . .** : :: :: * : .: :. :* : : .: : *:. .** ::..:.*:*: *. : : . :***::**:*.:******:*:.:****:*.:*:*** ****. ***:*: :**:******.***.:**:** :******:* . **:::*** :********** :***::: :*** :*:::*******: * *:*::**** ", "identical_positions": 99, "similar_positions": 76, "identity": "39.92%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120709-92", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8K071-1", "uniprot_id": "TM221_MOUSE", "id": "Q8K071-1", "name": "Transmembrane protein 221", "aln": "MGRSYGGRVLAAMTLLGIPAAVLVALAAQLLFQLQAGRAELRRVRTDGLHPELDPDAGLPEAAAGALLPLATALAALAQVLGLSCLLLAALCGHLGAELARG-PGPGRSDWFLYDCRLLRHSALGLFCCGVSVYLAALAIYALLLFEIEAGAAAASILGSGALILVAIMTHTLFRAVQATRRG----LRELSPPSFEDEPARPSEDSKSGCRAQPPQDEETETPIGAVTHQGSHF-----------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NGB7-1", "uniprot_id": "TM221_HUMAN", "id": "A6NGB7-1", "name": "Transmembrane protein 221", "aln": "MARSYGGRVLAAMTLLGIAAAVLAALGAQLLFQLQAGRAELRGLRAEGLGQELGAGPGLPEDAAGTLLPLAAALAALVLVLGFTCLLLAALCGHLGAELARG-PGPRRSDWFLYDCRLLRHVALGLFCCGISVYLAALSIYALLLFEIETGAAAASILGSGTLVLVAVLTHTLLRAARAARRG----LHELSPPSFEDDLARPAEVSKASPRAQPQQGIHRRTPYSTCPEPGDPFGSMATATAPAALEGGWESSLPASRMHRTLS----AGLGHWDGVTHEMRRMLGHRPGSMGKDSTLV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7EXZ1-1", "uniprot_id": "E7EXZ1_DANRE", "id": "E7EXZ1-1", "name": "", "aln": "MTHSYSQRSLVILAFLGILSSIMAVLSVILIFQLQTQQAVIK-----------DSPTFVPKDITAVLLPVSTVLSALSLTLNLSSVVVCLLHSYFATEICRGEPDTQRADWFLMDSRAVRHVTIGLFCLGVSVYLAAMSIYMVLVFEVETGIASVCVLSSGVLVLLLIIIHSLIRAARAAKHYRTDHLHTMYHNNPEQIRTSNLSIMENPRRQHSLANLPSHFINPAHMEPKSQYSTSNGPQAHSSDKDGCSGSGRTHRTLSTESGLFHAQAKPWNGVNSEMRSVLAR--KATIKDSTLV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* :**. * *. :::*** ::::..*.. *:****: :* :: .. . :*: :..***:::.*:** .*.::.:::. * .::.:*:.** *.. *:**** *.* :** ::**** *:******::** :*:**:*:* *:..:*.**.*:*: :: *:*:**.:*::: *: : . *: : . : * :. . . : . . : ", "identical_positions": 69, "similar_positions": 94, "identity": "23.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120709-93", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O54728-1", "uniprot_id": "PLB1_RAT", "id": "O54728-1", "name": "Phospholipase B1, membrane-associated", "aln": "MESWPGVSLVGLLLLLLLGQGPSQIHGSSGENTS--QPQQVFRTLKNFSFPCKPKKLELSVLSKSVHSLRPSDIKLVAAIGNLETPPAPGSGVVNMEKPQSLESELQNVCIGIMTALSDIIRHFNPSVLMPTCSPGKGTAGHTTIAEDLWIQAKELVRHLKDNPELDFEKDWKLITVLFSNTSQCHLCSSDQQKRHLMKHMEMLSGVLDYLHREVPRAFVNLVDLSEVLTMAQQHQETGFSPAPEICKCSEEITKLSKAVMQWSYQEAWEDLLASSKFNKHETFAVVFQSFFSEVELPLERPSP--QDSTTLALRIWNSMMEPVGRKDGTLNEAERKTMKCPSQESPYLFTYRNSNYQARQLKPIGKFQMKEGTKFTCPDKDPSDSIPTTVHRLRPADIKVIGAMGDSLTAGNGAGSSPGNVLDVLTQYRGLSWSVGGDETIETVTTLANILREFNPSLKGFSVGTGKENTPRASFNQAVAGAKSDGLAAQAKKLVSLMKDDKTINFQED--WKIITVFIGGNDLCGSCNNLARFSPQTFTDNIKTALDILHAEVPRAFVNMVSVIEITPLRELFNEPKVSCPRMILRSLCPCVLNLGENSAELAQLVERNRQYQEETGKLIESGRYDTRDDFTVVLQPMFENVVMPRTLEGLPDSSFFAPDCFHFNVKTHARSAIALWKNMLEPVGRKTRHQNFEIKVPIMCPNQTSPFLSTTKNSNLG--------------HGTSMSCEEKAPSASPPTSVHTLRPADIQVVAALGDSVTAGNGISSQEGDLADVTTQYRGLSYSAGGDKFLENVTTLPNILREFNGNLTGYSVGTGDVNSASAFLNQAVPGAKAENLASQVQTLIQKMKNDTRVNFHQDWKVITVMIGASDLCDFCKDSNRYSAANFSDHLRNALDILHKEVPRALVNLVDFMNPSIIRQVFLKNPDKCPVNQTSVLCNCVLTPGEDSHELARLEAFTKSYQSSMLQLVESGRYDTREDFSVVLQPFLFNIRLPILENGNPDTSFFAPDCILLSQKFHTQLARALWANMLEPLGKKMDTLDPKELIALACPTKDKPFLRTFRNSNYTY----PIKPAIENWGSDFLCTEQSPSSKVPTSVHELRPSDIKVVAAMGDFLTTATGARPSESSSLDTPWRGLSWSIGGDGTLETHTTLPNILKKFNPSILGFSTGT----LENTAGLNVAEEGARAQDMPAQAQALVKKMKSTPTINIQEDWKLITLLIGNNDLCLYCEDPEN--YSTREYVKYIQHALDIFYEELPRVFINVVEVMELSGLLHDQGGK-CAMPLAVQKNCSCLKRS-QNLMAMQELKKVNGNLQSALSELSYWHRYMQREDFAVTVQPFFRNTFVPLDERGGLDLTFFSEDCFHFSVRGHAEMAIALWNNMLEPVGKKTTSNNFTYNRTKLKCPSPENPFLYTVRNSQILLDKAKENSNTLY---------------WAVPVAAVGGLVVGILG---MMLWRTVRLVQ----------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TTY0-1", "uniprot_id": "PLB1_MOUSE", "id": "Q3TTY0-1", "name": "Phospholipase B1, membrane-associated", "aln": "MELYPGVSPVGLLLLLLLGQGPSQIHGSSGENTLAWQSQQVFWTLKNFPFPCKPKKLELSVLSESVHSLRPSDIKLVAAIGNPEIPLAPGSGTINMEKPQSIKNQPQDVCMGIMTVLSDIIRHFSPSVLMPTCSPGKGTAVHTT-AEDLWIQAKELVRRLKDNPQLDFEKDWKLITVFFSNTSQCHLCPSAQQKSHLMRHMEMLWGVLDYLHHEVPRAFVNLVDLSEVLAMDLQHQETGFSPAPEVCKCTETTT-LSKAVMQWSYQEAWEDLLASSKFNKHETFAVVFQPFFDEIEPPLKRSSP--QDPTTLALRIWNSMMEPVGQKDGLLNTAERKTMKCPSEESPYLFTYKNSNYQARRLKPITKLQMKEGSEFTCPDKNPSNSIPTTVHSLRPADIKIIGALGDSLTAGNGAGASPWNILDVLTEYRGLSWSVGGDETIKTVTTLPNILREFNPSLKGFSVGTGKESTSRASFNQAVAGAKSDGLAGQARKLVDLMKADKTINFQED--WKIITVFIGGNDLCASCSNSTRFSPQNFIDNIKNALDILHAEVPRAFVNMAMVMEITPLRELFNEPTVSCPRNILSRLCPCVLGLGDNSEELSSLVQRNRDYQKKTEELINSGRYDTRDNFTVVVQPLFENVSMPRTPEGVPDKSFFAPDCFHFNAKTHARSAIALWKNMLEPVGHKTRHNNFEIKAPIVCPNQASPFLSTTKNSNLG--------------NGTWMVCEERAPSASPPTSVHTLRPADIQVVAALGDSLTAGNGISSQEGNLTDVSTQYRGLSYSAGGDKTLENVTTLPNILRKFNGNLTGYSVGTGDSSSANAFLNQAVPGAKAENLTSQVRTLVQKMKSDNRVNFNRDWKVITVMIGASDLCDFCTDSNHYSAANFFDHLQNALDILHKEVPRALVNLVDFINPSIIREVFLKNPDKCPVNQSSVLCNCVLTPRKDSYELARLEAFTKSYQSSMLQLVESGRYDTREDFSVVLQPFLLNTKLPVLENGKPDTSFFAPDCIHLNQKFHTQLARALWANMLEPLGKKTDTLDPKGHISLACPTKDQPFLRTFRNSNYKY----PTKPAIENWGSDFLCTEKSPSSQVPTSVHELRPADIKVVAAMGDFLTTATGARPSGYKRLATPWRGLSWSIGGDGKLETHTTLPNILKKFNPSITGFSTGT----LDNKAGLNVAEEGARAQDMPAQAKTLVKKMKSTPTINLQEDWKLITLLIGNNDLCLYCENPED--NSTKEYVKYIQQALDILYEELPRVFINVVEVMELAGLHHVQGGK-CAMPLAVQKNCSCLRHS-QNLTAMQELKKLNWNLQSGISELSYWHRYMEREDFAVTVQPFFRNTFIPLNEREGLDLTFFSEDCFYFSDRGHAEMAIALWNNMLEPVGWKTSSNNFIYNRTKLKCPSPERPFLYTLRNSQLLPDKAEEPSNALY---------------WAVPVAAIGGLAVGILG---VMLWRTVKPVQQEEEEEDTLPNTSVTQDAVSEKRLKAGN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P1J6-1", "uniprot_id": "PLB1_HUMAN", "id": "Q6P1J6-1", "name": "Phospholipase B1, membrane-associated", "aln": "MGLRPGIFLL--ELLLLLGQGTPQIHTSPRKSTL--EGQLWPETLKNSPFPCNPNKLGVNMPSKSVHSLKPSDIKFVAAIGNLEIPPDPGTG--DLEK-QDWTERPQQVCMGVMTVLSDIIRYFSPSVPMPVCHTGKRVIPHDG-AEDLWIQAQELVRNMKENLQLDFQFDWKLINVFFSNASQCYLCPSAQQNGLAAGGVDELMGVLDYLQQEVPRAFVNLVDLSEVAEVSRQYHGTWLSPAPEPCNCSEETTRLAKVVMQWSYQEAWNSLLASSRYSEQESFTVVFQPFFYETTPSLHSEDPRLQDSTTLAWHLWNRMMEPAGEKDEPLSVKHGRPMKCPSQESPYLFSYRNSNYLTRLQKPQDKLEVREGAEIRCPDKDPSDTVPTSVHRLKPADINVIGALGDSLTAGNGAGSTPGNVLDVLTQYRGLSWSVGGDENIGTVTTLANILREFNPSLKGFSVGTGKETSPNAFLNQAVAGGRAEDLPVQARRLVDLMKNDTRIHFQED--WKIITLFIGGNDLCDFCNDLVHYSPQNFTDNIGKALDILHAEVPRAFVNLVTVLEIVNLRELYQEKKVYCPRMILRSLCPCVLKFDDNSTELATLIEFNKKFQEKTHQLIESGRYDTREDFTVVVQPFFENVDMPKTSEGLPDNSFFAPDCFHFSSKSHSRAASALWNNMLEPVGQKTTRHKFENKINITCPNQVQPFLRTYKNSMQG--------------HGTWLPCRDRAPSALHPTSVHALRPADIQVVAALGDSLTAGNGIGSKPDDLPDVTTQYRGLSYSAGGDGSLENVTTLPNILREFNRNLTGYAVGTGDANDTNAFLNQAVPGAKAEDLMSQVQTLMQKMKDDHRVNFHEDWKVITVLIGGSDLCDYCTDSNLYSAANFVHHLRNALDVLHREVPRVLVNLVDFLNPTIMRQVFLGNPDKCPVQQASVLCNCVLTLRENSQELARLEAFSRAYRSSMRELVGSGRYDTQEDFSVVLQPFFQNIQLPVLADGLPDTSFFAPDCIHPNQKFHSQLARALWTNMLEPLGSKTETLDLRAEMPITCPTQNEPFLRTPRNSNYTY----PIKPAIENWGSDFLCTEWKASNSVPTSVHQLRPADIKVVAALGDSLTTAVGARPNNSSDLPTSWRGLSWSIGGDGNLETHTTLPNILKKFNPYLLGFSTST----WEGTAGLNVAAEGARARDMPAQAWDLVERMKNSPDINLEKDWKLVTLFIGVNDLCHYCENPEA--HLATEYVQHIQQALDILSEELPRAFVNVVEVMELASLYQGQGGK-CAM-LAAQNNCTCLRHS-QSSLEKQELKKVNWNLQHGISSFSYWHQYTQREDFAVVVQPFFQNTLTPLNERGDTDLTFFSEDCFHFSDRGHAEMAIALWNNMLEPVGRKTTSNNFTHSRAKLKCPSPESPYLYTLRNSRLLPDQAEEAPEVLY---------------WAVPVAAGVGLVVGIIG---TVVWRCRRGGRRED------PPMSLRTVAL---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HRP9-1", "uniprot_id": "A0AC58HRP9_DANRE", "id": "A0AC58HRP9-1", "name": "Phospholipase B1, membrane-associated", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMAIKDKMFSSFAQIIIL------------ALLAS--------------------------------------------------------------------------WCSAVVPG--------------------------------------------------PLFCADSPASPSTPVSVHSLRPADVSVVSAIVLSEVESDRS------------------------DEIRALSMLSEILSTFNPHIS------------------AVLPDQR-----------SLMEKAEDMQFLDPTQWKLLLLFIPVDEISVCPDQDLTAVIDETVNRVEQTLDSLNEKLKHTLVHVVVWSGQSSDRVCQFK---------------CEQGYDENKCRLDMLVLMASLQESLSALLERRGWFNDQEDFSVMLQ----SSPVLTDPMTLP-----TPD----SSNDISLVVLQLWANLLQPITDNTEMDGWG-GVTVPCPTEEKPFLRTHQNSESRTSQTADSPLLVDPVMGSELNCEDMAPSPSIPTSVHALRPADIKVVAAIGDSLTAANGVGAAQNNLLGVITEYRGLSWCIGGDKNLSSITTLPNILKEFNPSINGYSVGKGDEDSAQSFLNQAVPGAKADDMVKQAHAVVKRMKEDSRIDFENDWKIITVFIGGNDLCAHCSDTRYYSSDNIVKYIREALDILHNEVPRALVNLVELLDIVPLRALHKDKSNGCPTWLVNIMCRCVLQPKDESHEFQTLQEFNKAYQRGMWELVDSGRYDTHDNFTVVLQPFLRNVFLPLMEDGRPDRSYFSPDCFHLSQKAHTLMARALWNNLMEPLGNKTDKEDFTAGISLKCPERSSPYLRTFHNSNYTYNIPEPSPPPPTNWGSDFSCVDTAPSNTLPTSVHSLRPGDIKVVAALGDSLTAGFGAKAKNILQLPDEERGVSWSIGGDDTLETVTTLPNIFKKFNPSVFGFSKGK----SKRPNGFNMAVGGAKAQNIPAQARDLITALKESKDVDFEKDWKLVTLFIGGNDLCQYCHDRAA--LSSSKYIGHIRDSLDMLYNEVPRVLVNLVEILQVEDLRMIKRDT-LGCSLLQKNMCPCFLSPRENSPQMNEMKKVNRDLQAETERLVYGGRYDGRHDFAVVLQPFFENTVVPMDKDGKPDVSFFSVDCFHFSERGHAEMAIAIWNNMLEPVGSKQNYNNFTYDRSKIRCPTEEHPFIFTRINSGPEVPMTTVPTTVLPGTPLPADCANDVVPAWAAAVLAVGGLMIGWIVTWMIFYYRERRNRKRNQ-----INEMSGTKF-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMM8-1", "uniprot_id": "Q9VMM8_DROME", "id": "Q9VMM8-1", "name": "Phospholipase B1, membrane-associated", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASITYALCLCSLFILFSPLVSANRRVRRQNRSDRLLADIGVR--------AQSYDPRVPENGIQQYTDIDQDLRHLFLNTRQTTLKWALNNIEALSS---RGRREGKLQAPVSKKVPFLCPTNN---TRSPSP---------------------------------PTSIEHLRPGDIDIIAAFGDSLSAGNGILSNNAIDMINEFRGLTFSGGGLANWRRFVTLPNILKIFNPKLYGFAVSNSLVINHRSSRLNIAEPMIMSRDLPFQARVLIDLLRRDRHVDMKRHWKLLTVYVGNNDICSDLCHWDTPQSFLDQHARDLRQAFRLLRDHVPRLLINLIVVPNIPLVLSTMTKVPLQCFVVHRVGCHCLINDRLNRTEFNERMDTLTRWQQLDMEIARLPEFR-RQDFAIVAHPMLTKLTAPTLPDGSTDWRFFSHDCFHFSQRGHAIISNLLWNSMLLPDDQKPRPSVVPELFERVVCPTAEQPYLVVRPS------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VW80-1", "uniprot_id": "Q9VW80_DROME", "id": "Q9VW80-1", "name": "Phospholipase B1, membrane-associated", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSSSRLICFGLLFLLAFGHVTSQR-----TSLDVALKNV--------------YRP----------------LRLLGLAFTGRSGDDPQN-VQRLQI---AGKTQK--SNPRTRALLEFCDADHGPGKRSPER---------------------------------PTSVHRLRPGDIDVIGAMGDSLTAGNGIFATNLLHVTVENRGVVWSIGGQYDWRKYLTLPNILKEFNPNLYGYAIKDGISTD-RSSRFDVAELAAMSRDMPHMAKVLVRRMQRDPRVNMTSDWKLVTLFIGNNDFCTDICYYPEPEKTVDWHERNMLKTYRYLRDNVPRLMLNIVPAPNLR-FLTNLTGLPPICYSTLRFECPCLMGKGKGQLDYLEG--IMKRWIAKDFEIANREEFN-TETFTINVQPFSQFQDFPRTRSGQTDTRFFSEDCFHLSQRGHAAAANSIWNNMLELPGHKS--GFATHLFETFRCPSEMRPFLITRENSRPEFVISSKK-------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * : * : . . . * . : * *: ***:. ***.**.::.*:** *::. * .. : **: :* ** . *****:* *** : *:: :::* ::::* * *: :: ::: .***:*: :* **:* : : .: : :.:** ::*:: :: . : * *: . * : .: . *:: :*: * * *** ***::* **** : :**.** . * . . **: *:: . . ", "identical_positions": 75, "similar_positions": 87, "identity": "4.91%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120709-95", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3Z8Z4-1", "uniprot_id": "D3Z8Z4_RAT", "id": "D3Z8Z4-1", "name": "", "aln": "MRSDPALMASFLLLLPLVLPGQPQLVRSVLSSMDESGTFQCVVHLPNSSIFLQQLEQLQSTLQELIGKYEQELSRVKEYAHVIEDQDSQTLELSHMLEARNPGVTLSQYDNPAFNLLRLELEGAQELAAQLKANGGVSGASDLLYELQNRVTNASLTLKLLVDSDRQSFHALQEEVDILEGQLSECEREKEQEQSSRHPGPPLAPGSCAHGGLQKVSRPLVVKLNWRGLSYKAGAWGRDSAPNPVSSLYWVAPLRADGRYFDYYRLHKSYDDLVLLKHYEQWKMG-------YGDGSGNTVYKNFMYFNYYGTRYMAKVDLSSNTLVLRRPLPGATYNNRFS---YACVPWTDIDFAGDEKGLWVFYATEESKGNLVVSLLNDSTLEVEQTWYTSQYKPALSGAFMACGVLYALRSLSTRQEEIFYAYDTTTGQEH-HLSILLDKMLETLHGINYCPWDHRLYVYNDGFLINYDLTFLTLKLPSSPMKRPSGAPAPFKPIKSNQPSRIRDSMTHQGPIRNMFSPSPLEGRFP", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M6Z4H1-1", "uniprot_id": "A0A8M6Z4H1_DANRE", "id": "A0A8M6Z4H1-1", "name": "", "aln": "-------MLSFLLLLTVTLSVESQKIPGEQKNDSCVCKLSSSIWAFPAVRFEKAMKQLQTCEENLT-EFQKRIRDVELPKMKLTLKNIKSRQKRSDFANRN-----DLYKSLHLQELILELEEIYNTATEVHKKNPSKTTNDLLKELT----KARKDVQNMYKSNVFNLETMQKRLRDLNNRVQSCKTIPEDFRS-----------TCHQRIMSRISSPVVTKLNSISKSYISGAWGRDAKPN-SKERYWEHCLVSGHKYGNTFRMYNSYEDFMGSKNYKDEYVASSYSHTNAVQGSGTILYDNTVFYQCYGKAEICSFNITT-QKTKRMKLDDAGIENTFPFCYYSCRDWTDIDLEADRDAVWVIYATMENHGNIVLSRLDPVELNITHTFKTHLFKRSVSSTFMVCGVLYATRFVNTYQEEVFYAFDTTTGQEINSLSLPFEKVSAGIANLNYNPVDRKLYMYNDGYLLAYNTFN-------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ******.:.*. :.* : . .. . .:.. : : * : ::***: ::* ::::.: *: : :: :: : : ** . *.. :: * **** : *:::: :. . :.*** ** :* :: : .*: .:.::*:.: *:.::..*: *: :* :* : :.::* *:*.*** . ** :******: ** .. ** * :. :* : :*:::**:*:: *:*:: :. :***. :*.* :::: **. :...:::: . * * .* :* *. *:* *****: .*...:**:*** *.:**:*:* *: *:: :*: * :* ::*.:**.****** * :.* ***:***:******* **: ::*: : .:** * *::**:****:*: *: ", "identical_positions": 137, "similar_positions": 165, "identity": "25.75%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120711-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R410-1", "uniprot_id": "M0R410_RAT", "id": "M0R410-1", "name": "", "aln": "MNSTPGDTRDAPAPSHPAPSHRQCLLPSVAHTPSVTEVTPAKKITFLKRGDPQFAGVRLAVHQRTFKTFSALMDELSQRMPLSFGVRSVTTPRGLHGLSALEQLQDGGCYLCSDRK--PPKTPRESGRLQRKSPPAGRSQVSQGGHEAPETSS--YSWKNPMAPRRLTLVKNGYPGCQQTVVLSHKNTRNLAGFLSKASELLRFPVKQVYTTHGKKVDSLQTLLDGPSLLVCAGNEAFRRLEMENDRGNRTRMVSGVTARSE------------RGCWGPNAKQSVIHSRGRSGGKLRQFSLMSERSGLS---DHPASGHQAWAGPALDRCPQDTPAPPGSLVAADDVEKKVCMNEDGSLSVEMKVRFQLLGEDTLRWSQRVGHASVFTAATGEDRDLREADRLCCRQEGYPWGVLEPGAQGLGPHDGGCQGAFDVGQQSRPSYDIWRNPLTAPEGTGPTPR-----------------------------------------------RRWGLAKLSRC---WREGTNDRKGHDKA------NASPVSTPRHPGSVQP-GSCCLWTPEVETGSDTLRPVSSASSRSETDLESGEDPCLEDTGPCG---------------------------------LRLQTQSIDRALSDTSASAESREESCEG--GGQLHRGSSQARVMASQGQATRGDNPCISTQRHLSLNHTGLQTKKDRQSASCQEVRGDPVLRLPLVPRHSGSRDTQRDALPAP------------ACAPAQRRQR---------------KQKRPAGVVCLPSVSIPHQVAQKGHARQCHCCRDTQSSGD--TALQMTMPMEREQACP----------GSPAPQFPSNSPRAGNQAPECLRPPFSSSLDFQEPQATSIAMSDSDCMSSFCH----PSTRSAEPAEDSKCQAPSSTPTPIHRGEVG------YLWDKAGSTPEPFSSSVLLNRWPEAD-LRTYQNFGCLQVAPTSTLATPSSQTQASISEACLGDN---SSCPTPPQDQICSRREPASSNSTHSDHGRADGYTG-----------------------PRRTLPGMPLGIRGSLEE-----------QEGDGGVTPSALPYTSPDAVVREWLGNIPEKPAL----MTYEVADETIEVPSEGPEGPKEDLGDGCSLKVFGELTQARQQM-----------------------LEGVTDEHPEPAGVPA----------------GPGSVCCKLGGDMHSDATSVERLKAPAEAG----------------TGEGTTVERGVSLCALPTRVSASTQIMKALLGSKPGRPSSLPEVSSTVAQRLSCSAGALIACLAKLHFFDEDLG--------PLDGKRRLEESPKYQEMLNISQTLWPGSELGQGQ---------------LDFSLRRLTSHQAL--LG-----TEDFTPTSSSGVDVSSGSGGSGEGSVPCVMDSTLASKKIDLPLKIPSQRPD-------------SRNQGYPEIVSPSTVSSG-----SQMRACTTSGEEAGKGGRKQTWGSAPEQSVEN---------------------------------------KVPEGDAQLEETEGRARERLQENSVL------------------------------------------GEGLPEEGTR-------------------------------VCSQGMLAANS----------------------------------------RDGAGSPEDTRVPNDEVGTD---GGLWPLDG--------------------------------------------------------------REDPTESPCHFEESNSRVSERQSAHVPELG------LDVRGGKQACVKAS-SETRETNTSIAHRGTLDPDPIWVSKLLKKIEKAFMAHLTDATAELRARWNLHDNNLLDQMVTELEQDVGQRLQASTVREVRKIQSRAGRMFPEPPREALRGQSSLQTEQRRRRLQGLRNLSAFP----GQGPLSFTLEDGATLGTALGTRSGAGLVEDEFCPCEICLKKKRTPRFPKDSTTVSGAPVRKAFDLQQILQSKKDGSSNREAMEVSPQKTGMMLSQEDPRTVQGADEKQELRLAQGLGVAEGEEGEGKQRMRAEEDTEFSKAEGDGCHAPKE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DATTKEDGKICIGTAQDGQQLEGTEIGKEETLHQSFRDGDTSEAP---------------------------------------------------------------------------------------------------------------------------------ARQGGHSVESQEASREGQPEVEGRNPDEKEESSWVSSEESQGRVGSENNSLDQEGRLQDHHQRPGPQSHHAARSSRAMSLDNCSQVS---QKGSDRDFPSGDLKYNKAKNSG------VLPAERKVPMMYPESSSSEQE-APSSPRPPKQEKGED---------GRSACTQVGGRVDGFGQDDLDF----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CGM2-1", "uniprot_id": "RP1L1_MOUSE", "id": "Q8CGM2-1", "name": "Retinitis pigmentosa 1-like 1 protein", "aln": "MNSTPGDTRDAPAPSHPAPSHRQCLLPSVAHTPSVTEVTPAKKITFLKRGDPQFAGVRLAVHQRTFKTFSSLMDELSQRMPLSFGVRSVTTPRGLHGLSALEQLQDGGCYLCSDRK--PPKTSREPGRLQRKSPSAGQAQVFQGGHEAPETS---YSWKGPVAPRRLTLVKNGDPRRQQTVVLSHKNTRSLAAFLGKASELLRFPVKQVYTTRGKKVDSLQTLLDGPSVLVCAGNEAFRCLEMENDRGNRTRKLSSVTARSE------------RGCWGPNAKQSVIHSRGRSGGKLRQVSLTSERSGLS---DHPASGHRAWAGPALDRCPQDMPVPPGSLVAADDVEKKVCMNEDGSLSVEMKVRFQLLGEDTLRWSQRVGQASVFTAASGKGQDPREADRFCCRQEGYPWGILKPGAQGLGSYDGGCQEAFDVGQKSQPSYDIWRNPLATPEGTGPTPR-----------------------------------------------RRWGLAKLSGCKSHWRQEANHRKGHDKD------NLSRVSTPRHPRSVQP-GSCCPWTPDGDTGSDTLHPVSSASSHNETDLESGEGLCLEDTGPHG---------------------------------SRPETQSTERALSDTSVSAKSREESSEG--GGQLHRSSSQARVMASREQVTKGDNPCISTQSHLPLNHMGLQTEKYRQGTRGWEVSGEPELRLALVPGHSGSQDTQRDALPAP------------ACAPAQWRQR---------------KQKRPASVECLPSVSVPYQVAQKGHARQDHYYRDTQSSLD--TALQMPMPQEREQACP----------GSPAPQSPSNSPSAGNQASEDLRSPFSSSLDLQEPQATSKATTIAVSGSDCVC----HSTRSVEPAGDTKCQAHSSTPTPAHRGELG------CLWDKAGTTPEPFSFSVLLDRCPEADDPRTYHDCCCLQAVPSSPLAAPSGQTQTSISEACLGGS---SFCPTPPKEQTCFGRESASNGSTSSGHSRADGFAG-----------------------PRRTLLVKSPGVRGSLEE-----------READGGVTPSALPYASPDAVVREWLGNIPEKPVL----MTYEMADENTEVPSDGPEGPKED-----SLKVLGEPSQAKQQP-----------------------PEGATNEHPEPAGVLS----------------GPGSVCCRLGGDLHPDATSGERLKAPAEAG----------------IGEGARVDHGVSLCALPTKVAASTQIMKALLGSKPGRPSSLPEVSSTVAQRLSSSAGAFIACLARLHFFDESLG--------PLDGKVRLEESPKYQEMLRLFQTLWPGSELWQGQ---------------LDFSLRKLTSHQAL--LG-----TEDFTPTSSSGVDVSSGSGGSGESSVPCVMDNTLAPEKRDLPLKIPSQRPD-------------SRNQGYPELVGHSTVSSV-----SQVRACATGGEETGKGGRKQTWGNAPEQSVHS---------------------------------------TMLEGDALSEETEGRVRERLQENSVH------------------------------------------GKGLPEEGVR-------------------------------VCSQEMLAAGS----------------------------------------QDGAGSPEDTRVPTDEAGADAASGGLWPLDG--------------------------------------------------------------REEPTESPQHFSESNSRVREHQSAHKLELGLEEVSRLDARGCKQACIKAS-SGT------MAHKGSLDPDPIWVSKLLKKIEKAFMAHLADATAELRARWDLHDNHLLDQMVTELEQDVGRRLQASTVMEVRKIQSRAGRMVPEPPREALRGQASLQTEQRRRRLQGLRNFSAVP----GQGPLSLTLEDGPTLKTALGTKSGAEPAEDEFCPCEICLKKKRTPRFPKDAATVSGAPVRKAFDLQQILQSKKGGSSNREAMEVAPQRTGRMLSQEDLGTVQGADEKQ------GLGVAEGEEGEGKQRLRAEEDPEILKTEGSGCCAPEE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DEATEEDGEICIGTAQESQQLEGTEMGKEGTLPQSFRDGGTLEAP---------------------------------------------------------------------------------------------------------------------------------ARQGTHSVEIQEASRERQQEVEGRHQDVKEDSPWVSSGESQGRVGSENTSLDQEGRLLNHHQRPGPQSHHTACSSRALSLDNSSQVS---QKGSDGDLTSGDLKCTKAKNSR------VLHAEKKVPVMYPERSSSEQE-VPSSPRLPKQGKGEDEGSA-----GSLACTQVGGKVDGFGQDDLDF----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWN7-1", "uniprot_id": "RP1L1_HUMAN", "id": "Q8IWN7-1", "name": "Retinitis pigmentosa 1-like 1 protein", "aln": "MNSTP---RNAQAP-----SHRECFLPSVARTPSVTKVTPAKKITFLKRGDPRFAGVRLAVHQRAFKTFSALMDELSQRVPLSFGVRSVTTPRGLHSLSALEQLEDGGCYLCSDKK--PPKTPSGPGRPQERNPTAQQLRDVEGQREAPGTS---SSRKSLKTPRRILLIKNMDPRLQQTVVLSHRNTRNLAAFLGKASDLLRFPVKQLYTTSGKKVDSLQALLHSPSVLVCAGHEAFRTPAMKNARRSEAETLSGLTSRNK------------NGSWGPKTKPSVIHSRSPPGSTPR----LPERPGPS---NPPVG-------PAPGRHPQDTPAQSGPLVAGDDMKKKVRMNEDGSLSVEMKVRFHLVGEDTLLWSRRMGRASALTAASGEDPVLGEVDPLCCVWEGYPWGFSEPGVWGPRPCRVGCREVFGRGGQPGPKYEIWTNPLHASQGERVAAR-----------------------------------------------KRWGLAQHVRCSGLWGHGTAGRERCSQD------SASPASSTGLPEGSEPESSCCPRTPEDGVDSASPSAQIGAERKAGGSLGEDPGLCIDGAGLGGPEQG---------------------------GRLTPRARSEEGASSDSSASTGSHEGSSEW--GGRPQGCPGKARAETSQQEASEGGDPASPALSLSSLRSDDLQAETQGQGT--EQATGAAVTREPLVLGLSCSWDSEGASSTPS------------TCTSSQQGQR---------------RHRSRASAMSSPSSPGLGRVAPRGHPRHSHYRKDTHSPLDSSVTKQVPRPPERRRACQ----------DGSVPRYSGSSSSTRTQASGNLRPPSSGSLPSQDLLGTSSATVTPAVHSDFVSGVSPHNAPSAGWAGDAGSRTCSPAPIPPHTSDSCSKSGAASLGEEARDTPQPSSPLVLQVGRPEQGAVGPHRSHCCSQPG---TQPAQEAQRGPSPEASWLCG----RYCPTPPRGRPCPQRRSSSCGSTGSSHQSTARGPGGSPQEGTRQPGPTPS-PGPNSGASRRSSASQGAGSRGLSEEKTLRSGGGPQGQEEASGVSPSSLPRSSPEAVVREWLDNIPEEPIL----MTYELADETTGAAGGGLRGPEVDPGDDHSLEGLGEPAQAGQQS-----------------------LEGDPGQDPEPEGALL----------------GSSDTGPQSGEGVPQGAAPEGVSEAPAEAG----------------ADREAPAGCRVSLRALPGRVSASTQIMRALMGSKQGRPSSVPEVSRPMARRLSCSAGALITCLASLQLFEEDLG--------SPASKVRFKDSPRYQELLSISKDLWPGCDVGEDQ---------------LDSGLWELTWSQALPDLGSHA-MTENFTPTSSSGVDISSGSGGSGESSVPCAMDGTLVTQGTELPLKTSNQRPD-------------SRTYESPGDLENQQQCCFPTFLNARACACATNEDEAERDSEEQRASSNLEQLAEN---------------------------------------TVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASS----------------------------------------PDGKGSQEDDPVQEEEAGRASASAEPCPAEG--------------------------------------------------------------TEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQAQPT-QGAAERSSSVACSAALDCDPIWVSVLLKKTEKAFLAHLASAVAELRARWGLQDNDLLDQMAAELQQDVAQRLQDSTKRELQKLQGRAGRMVLEPPREALTGELLLQTQQRRHRLRGLRNLSAFSERTLGLGPLSFTLEDEPALSTALGSQLGEEAEGEEFCPCEACVRKKVSPMSPKATMGATRGPIKEAFDLQQILQRKRGEHTDGEAAEVAPGKT--HTDPTSTRTVQGAEGGLGPGLSQGPGVDEGEDGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTPHQRPGSQTGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKSTG------TPHAERKATRMYPESSTSEQEEAPLGSRTPEQGASEGYDLQEDQALGSLAPTEAVGRADGFGQDDLDF----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BH38-1", "uniprot_id": "A0A8M2BH38_DANRE", "id": "A0A8M2BH38-1", "name": "", "aln": "MQRTAQGFFDADPHFHN-EPYQFPHPPTSSFGSIVTASSPVKRITFYKSGDSQFKGVKMAVHKRTFKCFDALLDDLSQKVPLPFGVRTITTPRGTHSIKHLEQFEDGGCYLCSDRRYVKPINMEEVGKRQAVWHHHSHPNNTRRKPSRPDEPLSGHQHHHHRHPKRIILVKNSDPAVRRSIILSRRTARSLRVFTEEISELMQCHVKRLYTLEGRKIDSIQSLMQCPSVLVCVGREPFRPLLVESLKKLSDEKLPGVGTRSHSSVCSEGHESKKNVNFGLETKKSIIHPRSDSSNRSTRFSLSSEKSYQNGLCTT----------PGQSGCVSTCPYVK-EVVMNDDIEKRVLVNKDGSLSVEMKVRFRLFNDETLQWSTEIKKSSMKVNESVKDTEYLQAKAEYSDPD---SVCASEAEEAFATKKHLEETLCQNCCNHCQEYDIWKNPMHKEQGASKSPSSSGSSQKITCKKSSVDSTRTISRSSGEYVEHVVEKASCFQETMEEGDTRVEYCSTSHCCSRSEVSSAGVTSKSKKSYEDGCGSQAKNKCSHTDITEAEISPTPHCELIKITGERPISAVSNSSKVLESLKEDQDDDYDDLPPSVSRASNWSQSCHPESDYQPKCARCRGLQSSPQSYLSPRPPSKESSTAIHSLKVKKHKTSFAAPVDGECMSTTSPVSKVSPMCNACQCGAISSVASGQEQLFEKGACRIISRQSQASCTSRGQANTPRSNASDALEKCDDAGKTSVTSGVPKRSGQSGGCSCCGKSKGFNGNVEEDEPEKADSILSKKSVACTSNVLEISDPVNNASDGEATRERSRSKISNASSTSKISKKSNCSAHERCSAGRSLKSERNEGESVKERTKSAMSAKSDCIISQRDPTPALVLTETDNAEEESQERAVSPMSAHSNLSAASKTSYKSISGHSEKAKTPRMCSPNDVEEVPLKLINSQGDEPESAASPNPTLSDNHNEQDTELPHEVRSASAMSNKSNQSSQHPSKDSKRSVKSCELQGKSPDVLCELKTEERQCRPLSNCSKTSVKSNESSKHSQAEAKSQERVPSAMSAKTNASKRSCRSCRANHNIPETTVTSVLNDATPDECATPTNKSKRATSPMSQTSEKSNACSERSIKSETQKTTLNALTVTSPLPRKKQSPSPRSTHNSKSKKTDSRAASGMSENSNVSRRSGKCNCLGSSNGDLKEKLKEDAKDVSGFPDKIPSDSTLINNIKSSDNQFDEPVSPTSTASVSLGLGEDQKGDDFDDLSTSGMSEDGGNRLHEVNGVDAEERPKTEASVNSHHKSPVQALLPVSAESVMSAELKKSKSGSQLNENNIRVPSTLSLSSSRSKSPSRLSPGSAKNTAMKERDCKAVNNTNHAERSEASSKHEQSERAAGKVTPASEFLDSSKASECSVKSKNGQSIRETDKRSKHSSHCLEMNGLDINSNRDLDDGMVKSLKASTSDKRSVKNDASRPNSAGKSDISQSLPLEMPNKKKASVKHPDSSSESVLSRALSAADLLREIVGSARPVSRGSKSVASSKNVDKVENKSQKSSRSKPSHSSEHNTKELMPSCLPNASPTEVVNDWLRNIPIGGYVYEMDVEHTEREAGENASQRDKSEAPESIMEVEEPNENPTGENHVQQETNDVEIQACDEKAQLEMCEMDHNPKTLANQDSLQKQCDSSVQVMKVLLGPKLDRSSSLPEVSPVYGRKLSQSAQGLLDCLANLRLIDSDSKDEKHRKYNEVMMILQSLWLQKPIEDEHIKQNAKVNQSEDEFNLRYSSGVDVNSGSTSSFKGEKIETSQGTIPPIEKQEISRNDKDDEEDEVKFTECLDSSKIIPDPVTPDIAERTQGSPVNTRQDDDQENDVTQEDVSSSENKNESDQTPQTTSYKSSGNESYTMKSPENTSSGTPPSVQKATLTKRVSQDPDPVWVLSLLKKLEKQFMLHYTDAMAEFKVRWDLDDNEMLNTMISELKEEVHKRIQSSINRELQKIQSRTGRGP-RPPGNALSRESTAQTEQRRKRLRVMRNKSILT--------------RSDEDYTASGTENSDQRSDDEYCPCDACIKKKLASRAAQRAQALSFAPVIMEFDLRKILQMKKDPVEPSQSKPEEQCTACQVENNLEVVHEEVEEVNDDTRGRDVKMADQEETDDADNAIDATLDSEKKDQNDEEANDKSD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DVDDGQNEKEAEPAKEEMGVNDTGDDENEEEGNLVEEDMEKEACTEHAPNIENS--------------------------------------------------------------------------------------------------------------------------------DSTAQKMTESAEETEAVDKQTTEDQSTEEVEESNKDDTPETTKGETPTIEKNADGTSDTGQDDETGKMPKVKIEMEVRESVEHEDKSSSVEEQNETDDALAKQATKTSTESQQGSMENCTAQAKLKDLQSFMESLESHGDSVVITKQPPYKEPHEAANQKD--MCNGLTEWQVSPKMNIRANKQKNQKNGH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: *. :* . .:: *: : . ** :*.*:*** * **.:* **::***:*:** *.:*:*:***::**.****::***** *.:. ***::*********:: * . *: * : . . . * . . : *:*: *:** * :::::**::.:*.* * : *:*:: **::** *:*:**:*:*:. **:***.*.*.** ::. : . :..: :*.. . :* ::* *:**.*. ... .*:. . *. . . * :* **::*:* :*:************:*..::** ** .: ::* . : :. :.. . : . . . . . : .*:** **: :* :. * .. * : .: . . .. . :. * . . . . : .* .. . :. .. * : : : * .. .:: * .*. .. . :. :. . . . : * . *. * . . . . * : .. :* . . :: * . . . . * *.. : : . .. . : . :.:.. . .. . . .: : .:. * * .. : : . . : . . . * . :: :. . : : ::. :..* . : :. . . . . : * . . * . * .. : * .* *. *.. . . *: : .: ..:* : . ..:* .. : . .::. * :* :. :. . . ...: . : . :.* ::. :: .* ..: *. ..... * . . .. :* * . : * *:*.: : * ** * . :: . : **.* . : *: : : * : *.:::: : *..:. :.. : . :.* * ..:: ..:. *:.. * :.... . .***: ..:: ** . : .. :: *.:.. ::. . ..:. .. .. .. : :. * : * ..* :: .* : . : .. ** . * . . .* :: * .: .. :.:* : : . .: . :: : * **:** **** ** *: * :.* **::.**.*.**.:*: * :**:::* :*:* * *::*:*.*:** .** :** : **:***:**: :** * .. ** *:. . :*:***: *::** :. .: : : .*: ***::*** *:. :: : . . : : . : * .:..: : *.: . :.. : : . .: : :: :: ** : .. * : . *:. : *.. : * . : . . . * .: . * .. .. . ::.. * : .::. . *: * : * *. : . : * : * . : :. : : .:.: : ", "identical_positions": 285, "similar_positions": 582, "identity": "10.11%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120711-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZT70-1", "uniprot_id": "D3ZT70_RAT", "id": "D3ZT70-1", "name": "", "aln": "MALLTPQGVKEVFQFQKPQGRQHLRRLLNWEEFDELRDARRSILLDTLYDSVIFAVGKGFPWVEVVQVVKFTEELLRETKGCSITEAVTILGKKLQDYQKQFNVTHLLALCDYFHNTFIRHYRLYQYVLSQDQEVNLTVAHVQMCTPPQPLPLTDGKDRDVWKHEQQVAELSAAEAEKRSDVLVLKETLRMEQAQMLQKAFGVEEAPTQLQPRPTLRREALERLVSEAIHIQIACLQELLQYEIQAAFDILDLRLQKKTLSLSAPPPPLPCITAGPAALEDSPKASKANKGKKAKAKK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80ZQ3-1", "uniprot_id": "CH074_MOUSE", "id": "Q80ZQ3-1", "name": "Uncharacterized protein C8orf74 homolog", "aln": "MALLTPQGVKEVFQFQKPQGRQHLRRLLNWEEFDELRDARQSILLDTLYDSVIFAVGKGFPWVEVVQVVKFTEELLKETKGCSITEAVTILGKKLRDYQKQFNVTHLLALCDYSHNTFIRHYRLYQYVLSQDQEVNLTVAHEQICAPPQPLPLTDGTDRDVWRHEQQVAELSTAEVEKRANVLMLKETLRMEQAQMLQKAFGVEEAPGQLQPHPTLRKEALERLVSEAIHIQIACLQELLQYEIQAAFDILDLRLQKKTLSLSAPPPPLPCITTGPAALEDSPKASKANKGKKAKAKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P047-1", "uniprot_id": "CH074_HUMAN", "id": "Q6P047-1", "name": "Uncharacterized protein C8orf74", "aln": "MALLTPQGVKEVFQLQRPQGRERLRRLLNWEEFDEQRDSRRSILLDTLYESIIFAVGKGFPWVEVAQVVKFTEELLRETKGCSITEAVTILGNKLRDYRGHFNTTHLLALCDYFHHTFIRHYKLYQYVLGQDQQVDLTVAHLEVCMPPHPLPLAEGMDRDLWIHEQQVATLTEAEAQKRADVLLLKEALRLERENSLQKAF---AAAAPAQPGQVLERQELESLICQAVHTQMELLQELLQRQIQNTFAILDLKLQKKTLNLNAPTPIPPPITS-HAGQEEALKPQRASKGKKAKARK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RRK3-1", "uniprot_id": "A0A8M1RRK3_DANRE", "id": "A0A8M1RRK3-1", "name": "", "aln": "-MMASIHTLQEISRMKRDEGIDRLSRCFEWMGFDG-DDKRQFLHQEFVYENVMFAVTRGLPWSTVGQVAIISKDLLPKINGLKSSEVISLVKAGLSQINPRLSATHHAVLLDFIVQTYVPHQRLYQAAFSGETSLKRISQDLQIETPPQPRPLSEGTDTERWKQQQILQELRLAQSRTQAEIQELRETSRTQIMSTLQDKL------HSLPDEGQISRQEVEELLHSFLRSQGEIMMESLTKETRLTENLLQVKLRQSEVQRQLAN------TPVFPEKQTSITPTRSKKKGN-----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : : ::*: :::: :* ::* * ::* ** * *: : : :*:.::*** :*:** * **. ::::** : :* . :*.:::: * : . ::..** .* *: :*:: * :*** .:. : .:. . :: **:* **::* * : * ::* : * *: ..:::: *:*: * : . **. : : :: :* *: . :: * : * * : : : :*:::*::. :. . . *. . : : .. ::.* : ", "identical_positions": 58, "similar_positions": 114, "identity": "19.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120711-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9H6D8-1", "uniprot_id": "FNDC4_HUMAN", "id": "Q9H6D8-1", "name": "Fibronectin type III domain-containing protein 4", "aln": "MPSGCHSSPPSGLRGDMASLVPLSPYLSPTVLLLVSCDLGFVRADRPPSPVNVTVTHLRANSATVSWDVPEGNIVIGYSISQQRQNGPGQRVIREVNTTTRACALWGLAEDSDYTVQVRSIGLRGESPPGPRVHFRTLKGSDRLPSNSSSPGDITVEGLDGERPLQTGEVVIIVVVLLMWAAVIGLFCRQYDIIKDNDSNNNPKEK-----GKGPEQSPQGRPVG-TRQKKSPSINTIDV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3TR08-1", "uniprot_id": "FNDC4_MOUSE", "id": "Q3TR08-1", "name": "Fibronectin type III domain-containing protein 4", "aln": "MP----LAPPANSVETMASLMPLSPYLSPTVLLLVSCDLGFVRADRPPSPVNVTVTHLRANSATVSWDVPEGNIVIGYSISQQRQNGPGQRVIREVNTTTRACALWGLAEDSDYTVQVRSIGLRGESPPGPRVHFRTLKGSDRLPSNSSSPGDITVEGLDGERPLQTGEVVIIVVVLLMWAAVIGLFCRQYDIIKDNDSNNNPKEK-----GKGPEQSPQGRPVGTTRQKKSPSINTIDV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FC68-1", "uniprot_id": "E7FC68_DANRE", "id": "E7FC68-1", "name": "", "aln": "-------------------MIQLVTFMS-LGLCLFGCHICFAGANRPAAPVNVSVTHLRADSATVSWNIPEGETVIGFAISQQRQDGLMQRFIREVNTTSRACILWDLDEDTDYIIQVQSVGLYGESLASKKIHFRTLKKSEHFQSTMMDQDDPAVEGLDISRHLQTGEILIIMTVLLMWAAVIVLFCKQYDIIKDNDSNNHSKEKSKPLSGQSTPEYHNGGLLGSKFQRTSSSVSIIKV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: * .::* * *..*.: *. *:**.:****:******:******::***: ***::******:* **.*******:*** **.* **:** :**:*:** *** .. ::****** *::: *. . .* :***** .* *****::**:.********* ***:************:.*** *:.. : :* :* . *:.*.*:. *.*", "identical_positions": 122, "similar_positions": 60, "identity": "50.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120717-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TD16-1", "uniprot_id": "BICD2_HUMAN", "id": "Q8TD16-1", "name": "Protein bicaudal D homolog 2", "aln": "MSAPSEEEEYARLVMEAQPEWLRAEVKRLSHELAETTREKIQAAEYGLAVLEEKHQLKLQFEELEVDYEAIRSEMEQLKEAFGQAHTNHKKVAADGESREESLIQESASKEQYYVRKVLELQTELKQLRNVLTNTQSENERLASVAQELKEINQNVEIQRGRLRDDIKEYKFREARLLQDYSELEEENISLQKQVSVLRQNQVEFEGLKHEIKRLEEETEYLNSQLEDAIRLKEISERQLEEALETLKTEREQKNSLRKELSHYMSINDSFYTSHLHVSLDGLKFSDD--AAEPNNDAEALVNGFEHGGLAKLP-LDNKTSTPKKEGLAPPSPSLVSDLLSELNISEIQKLKQQLMQMEREKAGLLATLQDTQKQLEHTRGSLSEQQEKVTRLTENLSALRRLQASKERQTALDNEKDRDSHEDG--DYYEVDINGPEILACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEKGRYEAEGQALTEKVSLLEKASRQDRELLARLEKELKKVSDVAGETQGSLSVAQDELVTFSEELANLYHHVCMCNNETPNRVMLDYYREGQGGAGRTSPGGRTSPEARGRRSPILLPKGLLAPEAGRADGGTGDSSPSPGSSLPSPLSDPRREPMNIYNLIAIIRDQIKHLQAAVDRTTELSRQRIASQELGPAVDKDKEALMEEILKLKSLLSTKREQITTLRTVLKANKQTAEVALANLKSKYENEKAMVTETMMKLRNELKALKEDAATFSSLRAMFATRCDEYITQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALTQRLELLELDHEQTRRG-------RAKAAP--------------------KTKPATPSL---------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q921C5-1", "uniprot_id": "BICD2_MOUSE", "id": "Q921C5-1", "name": "Protein bicaudal D homolog 2", "aln": "MSAPSEEEEYARLVMEAQPEWLRAEVKRLSHELAETTREKIQAAEYGLAVLEEKHQLKLQFEELEVDYEAIRSEMEQLKEAFGQAHTNHKKVAADGESREESLIQESASKEQYYVRKVLELQTELKQLRNVLTNTQSENERLTSVAQELKEINQNVEIQRGRLRDDIKEYKFREARLLQDYSELEEENISLQKQVSVLRQNQVEFEGLKHEIKRLEEETEYLNSQLEDAIRLKEISERQLEEALETLKTEREQKNNLRKELSHYMSINDSFYTSHLQVSLDGLKFSDDTVTAEPNNDAEALVNGFEHSGLVKSS-LDNKTSTPRKDGLAPPSPSLVSDLLSELHISEIQKLKQQLVQMEREKVGLLATLQDTQKQLEQARGTLSEQHEKVNRLTENLSALRRLQAGKERQTSLDNEKDRDSHEDG--DYYEVDINGPEILACKYHVAVAEAGELREQLKALRSTHEAREAQHAEEKGRYEAEGQALTEKISLLEKASHQDRELLAHLEKELKKVSDVAGETQGSLNVAQDELVTFSEELANLYHHVCMCNNETPNRVMLDYYREGQGKAG------RTSPEGRGRRSPVLLPKGLLATEVGRADGGTGDNSPSPSSSLPSPLSDPRREPMNIYNLIAIIRDQIKHLQAAVDRTTELSRQRIASQELGPAVDKDKEALMEEILKLKSLLSTKREQITTLRTVLKANKQTAEVALANLKSKYENEKAMVTETMMKLRNELKALKEDAATFSSLRAMFATRCDEYITQLDEMQRQLAAAEDEKKTLNSLLRMAIQQKLALTQRLELLELDHEQTRRG-------RSKAAS--------------------KAKPASPSL---------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AA52Z2I8-1", "uniprot_id": "A0AA52Z2I8_DANRE", "id": "A0AA52Z2I8-1", "name": "", "aln": "MSGDEDGCPGAQLVTEAGPNWLRAEIERLSRELSETSREKIQAAEYGLVVLEENQQLKQRFEELESEYETVRQELDQLREAYGQVHSTHRKVAADGESREESLILESASKEAYYEQRVQELQSDLRQAKNTLTGTQAENERLATLALELRENNEIVELQRSRLRDDIREYKIRESRLLQDYTELEEENISLQKQVSTLKQGQVEFEGLKHENRRLEEEVQYLNSQLEDAIRLREIADRQLTEALETVKTEREQKAALRKELTHHMTLGDSLLAS----SLDGLKLSAD----EPNNDDAILTLENGFAKVCEGNDEDNRLSSPKRDENFRPAPSLVDDLLTELNISEIQKLKQQLLQVEREKVALLTTLQDSQKQLEHARGALAEQQEAMTRLSDDLGAMRRLQAGKERQSALDSERERDSREDNDVDYYELDINGPEILRCKYEVAIAEAGELREELKGLKSEHDEMKTEHEEVRTRLEGHVRDLSIQVSQLEYSSRTDRDKVAKLEKELKEVSAVAGETEGSLSVAQDELVAFSEELANLYHHVCMCNNETPNRVMLDFYKEGKGSKT----------ETKDRQS--------TLTQTNESKGQT-----SRSNSIPVDREEPRPEPMDVYNLVAIIRDQIRHLQKAVDRTTELSRQRVASLELAAVADKDQAACMEEILKLKSLLSTKREQIATLRTVLKANKQTAEVALANLKSKYENEKAMVTETMMKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDDMQRQLAAAEDEKKTLNSLLRMAIQQKLALTQRLEDLEFDNEQSRRGSGAGPGGRGKAPSGRGRGPLSFSSPHVSPRLPCKNRPQPHGLIGSPAVFCSEKYKILCDTGSD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**. .: *:** ** *:*****::***:**:**:***********.****::*** :***** :**::*.*::**:**:**.*:.*:************** ****** ** ::* ***::*:* :*.**.**:*****:::* **:* *: **:**.******:***:**:******:**************.*:*.********** :*****.:************:**::*** *****:******* *****:*:*::.**: :* ******:* * ***** *. .. : : **: *:*::: *:****.***:**:***********:*:****..**:****:*****::**:*:**:* :.**:::*.*:*****.****::**.*::***:**. ****:******** ***.**:********:**.*:* *: :::* * : * *.. : *: ::* ** :*: **: :*:******:** *****:***.*******:**************************:*:**:* * :.*:* .:...:.* * * ..*:* .:** ***::***:*******:*** ************:** **....***: * ******************:******************************************************************:****:********************************** **:*:**:*** *.**.. * :* . .* ", "identical_positions": 548, "similar_positions": 170, "identity": "62.49%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120718-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P23606-1", "uniprot_id": "TGM1_RAT", "id": "P23606-1", "name": "Protein-glutamine gamma-glutamyltransferase K", "aln": "-MEGPRSDVGRWGRSPWQP-TTPSPEPEPEPEPDRSSRSRRGGGRSFWARCCGCCSCGNRADDDWGPEPSGSRSRGTSSRGGGSRGGDSRGRDSRGG--RRPESRGSGVNAAGDGTIREGMLVVNGVDLLCSRSDQNRREHHTDEFEYDELILRRGQPFHIILFLNREYESS-DRIALELLIGNNPEVGKGTHVIIPVG-------KGGSGGWKAQVTKTNGHNLTLRVHTSPNAIIGKFQFTVRTRSEAGEFQLPFDPRNEIYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQFDHGVLDACLYILDRRG-MPYGGRGDPVSVSRVVSAMVNSLDDNGVLIGNWTGDYSRGTNPSAWVGSVEILLSYLRTG-YSVPYGQCWVFAGVTTTVLRCLGLATRTVTNFNSAHDTDTSLTMDIYFDENMKPLEHLNHDSVWNFHVWNDCWMKRPDLPSG----FDGWQVVDATPQETSSGIFCCGPCSVESIKNGLVYMKYDTPFIFAEVNSDKVYWQRQD-DGSFKIVYVEEKAIGTLIVTKAINSNMREDITHIYKHPEGSEAERKAVEKAAAHGSKPNVYATRDS-----------------------------AEDVAMQVEAQD--AVMGQDLTVSVVLTNRGSSRRTVKLHLYLCVTYYTGVSGPTFKETKKEVVLAPGASDTVAMPVAYKEYKPHLVDQGAMLLNVSGHVKESGQVLAKQHTFRLRTPDLSLTLLGAAVVG-QECEVQIVFKNPLPITLTNVVFRLEGSGLQRPKVLNVGDIGGNETVTLRQTFVPVRPGPRQLIASLDSPQLSQVHGVIQVDVAPSSG-GRGFSEAVGDSRSGENIPMAFRGGA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9JLF6-1", "uniprot_id": "TGM1_MOUSE", "id": "Q9JLF6-1", "name": "Protein-glutamine gamma-glutamyltransferase K", "aln": "-MEGPRSDVGRWGRSPWQPPTTPSPEPEPEPEPDRRSRSRRGGGRSFWARCCGCCSCGNRGDDDWGPEPSGSRSRGTSSRG----------RDSRGG--RRPESRGSGVNAAGDGTIREGMLVVTGVDLLCSRSDQNRREHHTDEFEYDELIVRRGQPFHMILFLNREYESS-DRIALELLIGSNPEVGKGTHVIIPVG-------KGGSGGWKAQVTKNNGHNLNLRVHTSPNAIIGKFQFTVRTRSEAGEFQLPFDPRNEIYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQFDHGVLDACLYILDRRG-MPYGGRGDPVSVSRVVSAMVNSLDDNGVLIGNWTGDYSRGTNPSAWVGSVEILLSYLRTG-YSVPYGQCWVFAGVTTTVLRCLGFATRTVTNFNSAHDTDTSLTMDIYFDENMKPLEHLNHDSVWNFHVWNDCWMKRPDLPSG----FDGWQVVDATPQETSSGIFCCGPCSVESVKNGLVYMKYDTPFIFAEVNSDKVYWQRQD-DGSFKIVYVEEKAIGTLIVTKAIHSNNREDITHIYKHPEGSEAERRAVEKAAAHGSKPNVYATRDS-----------------------------AEDVAMQVEAQD--AVMGQDLAVSVVLTNRGSSRRTVKLHLYLCVTYYTGVSGPTFKEAKKEVTLAPGASDSVTMPVAYKEYKPHLVDQGAMLLNVSGHVKESGQVLAKQHTFRLRTPDLSLTLLGAAVVG-QECGVQIVFKNPLPVTLTNVVFRLEGSGLQRPKVLNVGDIGGNETVTLRQTFVPVRPGPRQLIASLDSPQLSQVHGVIQVDVAPASG-GSGFSDAGGDSRSGENIPMAYRGGA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22735-1", "uniprot_id": "TGM1_HUMAN", "id": "P22735-1", "name": "Protein-glutamine gamma-glutamyltransferase K", "aln": "MMDGPRSDVGRWGGNPLQPPTTPSPEPEPEPD----GRSRRGGGRSFWARCCGCCSCRNAADDDWGPEPSDSRGRGSSSGT--------RRPGSRGSDSRRPVSRGSGVNAAGDGTIREGMLVVNGVDLLSSRSDQNRREHHTDEYEYDELIVRRGQPFHMLLLLSRTYESS-DRITLELLIGNNPEVGKGTHVIIPVG-------KGGSGGWKAQVVKASGQNLNLRVHTSPNAIIGKFQFTVRTQSDAGEFQLPFDPRNEIYILFNPWCPEDIVYVDHEDWRQEYVLNESGRIYYGTEAQIGERTWNYGQFDHGVLDACLYILDRRG-MPYGGRGDPVNVSRVISAMVNSLDDNGVLIGNWSGDYSRGTNPSAWVGSVEILLSYLRTG-YSVPYGQCWVFAGVTTTVLRCLGLATRTVTNFNSAHDTDTSLTMDIYFDENMKPLEHLNHDSVWNFHVWNDCWMKRPDLPSG----FDGWQVVDATPQETSSGIFCCGPCSVESIKNGLVYMKYDTPFIFAEVNSDKVYWQRQD-DGSFKIVYVEEKAIGTLIVTKAISSNMREDITYLYKHPEGSDAERKAVETAAAHGSKPNVYANRGS-----------------------------AEDVAMQVEAQD--AVMGQDLMVSVMLINHSSSRRTVKLHLYLSVTFYTGVSGTIFKETKKEVELAPGASDRVTMPVAYKEYRPHLVDQGAMLLNVSGHVKESGQVLAKQHTFRLRTPDLSLTLLGAAVVG-QECEVQIVFKNPLPVTLTNVVFRLEGSGLQRPKILNVGDIGGNETVTLRQSFVPVRPGPRQLIASLDSPQLSQVHGVIQVDVAPAPGDGGFFSDAGGDSHLGETIPMASRGGA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32THJ9-1", "uniprot_id": "A0AB32THJ9_DANRE", "id": "A0AB32THJ9-1", "name": "Protein-glutamine gamma-glutamyltransferase K", "aln": "--------------------------------------------------------------------------------------------------------MGTTVEAS------DAVLQVRSVDLIKTRKGQNRQEHHTDAFFSNHLIIRRGQCFQMTIELSRPLIPNKDQLYLELRLGNVVPAHRDSFVSVPIVS------EFKKNAWEAKIIEQAKTTIKLSVYSLPTACIGQYKLTVVTNCPAGKATSPYTPDNDIYMLFNPWCKDDPVYLKDEAERNEYVLNDMGKMYYGTEQQIGTRTWNFGQFDEGVLEACFFVLEKSG-SPCSGWGDPINVVRVISALVNSNDDQGVLIGNWKNSYEGGLSPTAWSGSSPILKQYHKSGGTPVKFGQCWVFAGVTNTMLRCFGVPTRPVSNFSSAHDTDVSLTTDVYLDEKLEEIKDLNRDSIWNFHVWNESWMTRPDLPAG----FGGWQVVDATPQETSQGVFRCGPTSVAAVRSGQVYLKYDTPFVFAEVNSDKVFWQRQS-NGSFTVIKVDENAVGHCISTKAVGSDQRVDITHLYKHPEGSSEERSAVEAACSFGSKRSIYLPRSSSNSSNSSSNSSSSSSSSSSSSSSGSSNAAGADVTVDVVMEDSGACLGQDAVLFIVLKNRSSSARTVDLQSRVEAVDYTEHHKAFLRKDQTRAQLKPHEIQSLEWILQYEEYKEELEGQTSLLLSLSGRITETKQTLVKHFTFRLRTPDLVLTPVGDAVVG-QELKVKLKFQNPLVSVLRNVIFRMEGLGLQHVKTIHYGDITGGATVRLTEIFVPKRSGPQKLLATLDCPQLTQVHGVANILVKHR----------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLU2-1", "uniprot_id": "Q9VLU2_DROME", "id": "Q9VLU2-1", "name": "protein-glutamine gamma-glutamyltransferase", "aln": "----------------------------------------MGQKLSCCQKCGDWKWCTSKDNEESTLRIRNANAN---------------------------YFTGIPQGDKTDGASSAVLGVLKVDLCLEDNHEEHHTSHFYAAAAKEALVVRRGEPFRLKIHFNRDYSPSKDAISFIFTVADDTKPSPGHGTLNALVPHDGIDYLGDTLEWGAGIESHEGQTLTVLIKPPSTCPVTEWKLDIDTKLLG-DGSRSYPLPLPIYVLFNPWCPDDQVYLEDRDQRKEYVMHDTTLIWRGSYNRLRPSVWKIGQFERHVLECSLKVLGTVGRIPPAYRGDPVRVARALSALVNSVDDDGVLLGNWSEDFSGGVAPTKWTGSVEILQQFYKTQ-KSVKFAQCWNFSGVLTTIARSLGIPSRIITCYSSAHDTQASLTVDVFIDANNKKLDAETTDSIWNYHVWNELWMQRPDLGVGEHGTFDGWQVVDATPQEASDNMYRVGPASVAAVKNGDILRPFDGGFVFAEVNADKLYWRYNGPSQPLKLLRKDTLAIGHLISTKAVLKWEREDITDTYKHAERSEEERSTMLKALKQSRHAFSRYYLNDN----------------------------FNDIEFDMELKDDIKIGQSFSVVLKVSNKSESRTHMATGQISCDAVLYTGVGAVEVKTLGFELELEPKSSDYVRMEVIFEEYYDKLSSQAAFQISAAAKVKDTDYDYYAQDDFRVRKPDIKFQLGEAAIVAQKELDVILRLENPLPIPLHKGVFTVEGPGIEQPLKFKIAEIPVGGTAAATFKYTPPYAGRGTMLAKFTSKELDDVDGYRHYEIEPRPE---DLLQPNGSHRSSNIIRRRTDVIA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : : . ::: .*. : *::***: *:: : :.* .. * : : : :.. . . .: . * * : . .:.: : . ... : :::: : *. . . .: **:****** :* **:... *:***::: :: *: :: .*: ***:. **:..: :* * * . ***: * *.:**:*** **:***:***. .:. * *: * ** ** .: :: .* :.*** *:** .*: *.:*..:* :: :.*****:.*** *:::* : : :. . **:**:****: ** **** * *.***********:*..:: ** ** :::.* : :* *:*****:**::*: :. . .:.:: : *:* * ***: . * *** ***.* *. ** :: * . : .. *: .:: :* . : : : * : . : .. ** .: . * * : : : ::** .* .* :: :. :.::.:: : **:*.**: : *:*. :* * : ::*** * : :* :** *::: :: .:* . *. :.* .* ::*.: . :* :*.* : : ", "identical_positions": 180, "similar_positions": 229, "identity": "20.55%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120718-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O95932-1", "uniprot_id": "TGM3L_HUMAN", "id": "O95932-1", "name": "Protein-glutamine gamma-glutamyltransferase 6", "aln": "--------------------------------------------MAG------IRVTKVDWQRSRNGAAHHT----QEYPCPELVVRRGQSFSLTLELS--RALDCE-EILIFTMETGPRASEALHTKAVFQTSE----LERGEGWTAAREAQMEKTLTVSLASPPSAVIGRYLLSIRLSSHRKHS-NRRLG-EFVLLFNPWCAEDDVFLASEEERQEYVLSDSGIIFRGVEKHIRAQGWNYGQFEEDILNICLSILDRSPGHQNNPATDVSCRHNPIYVTRVISAMVNSNNDRGVVQGQWQGKYGGGTSPLHWRGSVAILQKWLKGRYKPVKYGQCWVFAGVLCTVLRCLGIATRVVSNFNSAHDTDQNLSVDKYVDSFGRTLEDLTEDSMWNFHVWNESWFARQDLGPS----YNGWQVLDATPQEESEGVFRCGPASVTAIREGDVHLAHDGPFVFAEVNADYITWLWHE-DESRERVYSNTKKIGRCISTKAVGSDSRVDITDLYKYPEGSRKERQVYSKAVNRLFG---------VEASGRRIWIRRAGGRCLWRDDLLEPATKPSIAGKFKVLEPPMLGHDLRLALCLANLTSRAQ-----RVRVNLSGATILYTRKPVAEILHESHAVRLGPQEEKRIPITISYSKYKEDLTEDKKILLAAMC-LVTK-GEKLLVEKDITLED-FITIKVLGPAMVG-VAVTVEVTVVNPLIERVKDCALMVEGSGLLQEQLSIDVPTLEPQERASVQFDITPSKSGPRQLQVDLVSPHFPDIKGFVIVHVATAK------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1M4T7-1", "uniprot_id": "F1M4T7_RAT", "id": "F1M4T7-1", "name": "Protein-glutamine gamma-glutamyltransferase E", "aln": "--------------------------------------------MAG------VRITKVDWQHSENGAAHHT----QDYPCPELVVRRGQLFSLTLDLN--RALDSE-EALIFTVETGPHASEALHTKAIFQTAE----LEIGDTWTAAKEEQTENTITVSLSSPSNAVIGRYLLSARAASRRKHS-DRKLG-QFILLFNPWCPEDDVFLDSEEERQEYVLNDSGIIFRGVEKHIRAQGWNYGQFEEDILNICLSILDRSPSHQDDPATDVSHRHDPVYVTRIISAMVNSNNDRGVVQGQWQGKYGGGTNPLNWRGSVAILQKWFKGKYKPVKYGQCWVFAGVMCTVLRCLGIATRVVSNFNSAHDTDGNLSVDKYVDSYGRTLEDLTEDSMWNFHVWNESWFARQDLGSS----YDGWQVLDATPQEESEGTFQCGPASVTAIREGDVHLAHDGPFVFAEVNADYITWLWHE-DKRRERVYSDTKKIGRCISTKAVGSDSRVDITGLYKYPEGSRKERQVYGKALKKLLS---------VEAWGRRRRIRRASVRGIWRDDLLEPVTKPSITGKFKVLEPPVLGQDLKLALCLTNLTTRAQ-----RVRVNVSGATILYTRKPVAEILRESHTMKLGPLEEKRIPVTISYSQYKEDLTEDKKILLAAMC-LVSK-GEKLLVEKDITLED-FITIKVLGPAVVG-VTVAVEVLVINPLSESVKDCVLMVEGSGLLQGQLSVEVPSLKPQERALIQFNITPSKSGPRQLQVDLVSSQFPDIKGFVIIHVATAK------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A0G2K142-1", "uniprot_id": "A0A0G2K142_RAT", "id": "A0A0G2K142-1", "name": "Protein-glutamine gamma-glutamyltransferase 5", "aln": "--------------------------------------------MAQ-----GLEVALTDLQSSRNNVRHHT----EEISFDRLVVRRGQAFCITLYFKN-RGFQPGMDSIMFVAETGPLPDLAKGTRAVFSLTG----SGGSSPWIASLEANRANSLEVSLCAPPMAAVGRYLLKVRIDSYQGSVTAYQLG-EFILLFNPWCPADTVYLESEPQRQEYVVNDYGFIYQGSKSWIRPCPWNYGQFEENIIDICLELLEKSLNFQVDPSTDCALRGSPVYISRVVCAMINSNDDSGVLNGNWSENYMDGANPAEWTGSVAILKQWHATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVITNFDSGHDTDGNLIIDEYYDNTGRILENMKKDTVWNFHVWNECWMARKDLPPG----YGGWQVLDATPQETSNGLYCCGPASVKAIKEGEVDLNYDTRFAFSMVNADCMSWLVYG-GKEQK-LHQDTATVGNFISTKSIQSDERDDVTENYKYEEGSLQERQVFLKALQKLQAGRSQGPHQ-ANSNPFSSMPPRQDSARSPTTPSLRPSDVLQVSLKFELLDSPKMGQDINFVLLAVNMSPQFK-----DLKLNLSAQSLLHDGSPLAPFWQDTAFITLFPKEEKTYPCKILYSQYSQYLSTDKLIRISALG-EEKSSPEKILVNKIITLTFPGIMINVLGAAFVN-QPLTVQVVFSNPLSEPVEDCVLTLEGSGLFRKQQRVLIGVLKPHNKASITLKTVPFKSGQRQIQANLRSNRFKDIKGYKNVYVDIGL------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D7I9-1", "uniprot_id": "TGM5_MOUSE", "id": "Q9D7I9-1", "name": "Protein-glutamine gamma-glutamyltransferase 5", "aln": "--------------------------------------------MAQGCPITGLEVALTDLQSSQNNVRHHT----EEISVDRLVVRRGQAFSITLYFKN-RGFQPGMDSIMFVAETGPLPDLAKGTRAVFSFTG----SGGPSPWIASLEANRANSLEVSLCAPPIAAVGRYLLKIRIDSYQGFVTAYQLG-EFILLFNPWCPADSVYLESEPQRQEYVVNDYGFIYQGSKSWIRPCPWNYGQFEENIIDICLELLEKSLNFQVDPSTDCALRGSPVYTSRVVCAMINSNDDNGVLNGNWSENYVDGINPAEWTGSVAILKQWHATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVITNFDSGHDTDGNLIIDEYYDNTGRILENMKKDTVWNFHVWNECWMARKDLPPG----YGGWQVLDATPQETSNGLYCCGPASVKAIKEGEIDLNYDTRFAFSMVNADCMSWLVYG-GKEQK-LHQDTATVGNFISTKSIQSDERDDITESYKYEEGSLQEREVFLKALQKLQATRSQGPHQ-ANSNPFSSVPPRHNSARSPDSPSLQPSDVLQVSLKFELLDSPKMGQDINFVLLAVNMSPQFK-----DLKLNLSAQSLLHDGSPLVPFWQDTAFITLFPEEEKSYPCKILYSQYSQYLSTDKLIRISALG-EEKNSPEKILVNKIITLTFPGIMINVLGAAFVN-QPLTVQVVFSNPLSEPVEDCVLTLEGSGLFRKQQRVLIGVLKPHHKASITLKTVPFKSGQRQIQANLRSNRFKDIKGYKNVYVDIGL------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43548-1", "uniprot_id": "TGM5_HUMAN", "id": "O43548-1", "name": "Protein-glutamine gamma-glutamyltransferase 5", "aln": "--------------------------------------------MAQ-----GLEVALTDLQSSRNNVRHHT----EEITVDHLLVRRGQAFNLTLYFRN-RSFQPGLDNIIFVVETGPLPDLALGTRAVFSLAR----HHSPSPWIAWLETNGATSTEVSLCAPPTAAVGRYLLKIHIDSFQGSVTAYQLG-EFILLFNPWCPEDAVYLDSEPQRQEYVMNDYGFIYQGSKNWIRPCPWNYGQFEDKIIDICLKLLDKSLHFQTDPATDCALRGSPVYVSRVVCAMINSNDDNGVLNGNWSENYTDGANPAEWTGSVAILKQWNATGCQPVRYGQCWVFAAVMCTVMRCLGIPTRVITNFDSGHDTDGNLIIDEYYDNTGRILGNKKKDTIWNFHVWNECWMARKDLPPA----YGGWQVLDATPQEMSNGVYCCGPASVRAIKEGEVDLNYDTPFVFSMVNADCMSWLVQG-GKEQK-LHQDTSSVGNFISTKSIQSDERDDITENYKYEEGSLQERQVFLKALQKLKARSFHGSQRGAELQPSRPTSLSQDSPRSLHTPSLRPSDVVQVSLKFKLLDPPNMGQDICFVLLALNMSSQFK-----DLKVNLSAQSLLHDGSPLSPFWQDTAFITLSPKEAKTYPCKISYSQYSQYLSTDKLIRISALG-EEKSSPEKILVNKIITLSYPSITINVLGAAVVN-QPLSIQVIFSNPLSEQVEDCVLTVEGSGLFKKQQKVFLGVLKPQHQASIILETVPFKSGQRQIQANMRSNKFKDIKGYRNVYVDFAL------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q96PF1-1", "uniprot_id": "TGM7_HUMAN", "id": "Q96PF1-1", "name": "Protein-glutamine gamma-glutamyltransferase Z", "aln": "--------------------------------------------MDQ---VATLRLESVDLQSSRNNKEHHT----QEMGVKRLTVRRGQPFYLRLSFS--RPFQSQNDHITFVAETGPKPSELLGTRATFFLTR----VQPGNVWSASDFTIDSNSLQVSLFTPANAVIGHYTLKIEISQGQGHSVTYPLG-TFILLFNPWSPEDDVYLPSEILLQEYIMRDYGFVYKGHERFITSWPWNYGQFEEDIIDICFEILNKSLYHLKNPAKDCSQRNDVVYVCRVVSAMINSNDDNGVLQGNWGEDYSKGVSPLEWKGSVAILQQWSARGGQPVKYGQCWVFASVMCTVMRCLGVPTRVVSNFRSAHNVDRNLTIDTYYDRNAEMLSTQKRDKIWNFHVWNECWMIRKDLPPG----YNGWQVLDPTPQQTSSGLFCCGPASVKAIREGDVHLAYDTPFVYAEVNADEVIWLLGD-GQAQEILAHNTSSIGKEISTKMVGSDQRQSITSSYKYPEGSPEERAVFMKASRKMLG-------------PQRASLPFLDLLES---GGLRDQ---PAQLQLHLARIPEWGQDLQLLLRIQRVPDSTHPRGPIGLVVRFCAQALLHGGGTQKPFWRHTVRMNLDFGKETQWPLLLPYSNYRNKLTDEKLIRVSGIA-EVEETGRSMLVLKDICLEPPHLSIEVSERAEVG-KALRVHVTLTNTLMVALSSCTMVLEGSGLINGQIAKDLGTLVAGHTLQIQLDLYPTKAGPRQLQVLISSNEVKEIKGYKDIFVTVAGAP----------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BAQ1-1", "uniprot_id": "A0A8M3BAQ1_DANRE", "id": "A0A8M3BAQ1-1", "name": "Protein-glutamine gamma-glutamyltransferase 2", "aln": "-------------------------------------------MCSSSSSNTPDQGVRVDLECVKNNTDHHT----HEITQERLIIRRGQAFSLKISAE-----NIQQNHISITAETGPGASEVKHTLFSFSTQS----STNP----AQVCSRSESSVSLALVFPSDAPVGRYSVCVKHGS------SSCMN-TLTLLFNPWCKDDHVYLPSEAERQEYIMSEQGVLYKGVDEYITSMNWDYGQFEEDIVDICLKLLDLNPKCLKDPQEDYSARCNPVYVSRVVSAMINCNDDQGVLAGQWGDSYTGGVPPSRWSSSVEILRRWVKYNCSPVKYGQCWVFAAVMCTVLRCLGIPCRVVTNYQSAHDTDRNLVVDEYFSDYGVRPKN-SQDSVWNFHVWVEAWMRRPDLTEDTL--YDGWQVLDPTPQEKSSGTYCCGPAPVMAILEGHTEVKYDVPFVFAEVNADRVCWLLMT-DGSRKKIMSDSRSVGQNLSTKAVGSSSRLDITDLYKHGEGSAQERAVYTEAVHRLTD------------------------------LQIPESPPVSVQMRLSLDVPPLNGADVPLKLFLK--GSRTQ-----CVCVNISAQVMRYTGAPAAAVWSHSTDVQLQDTEEKALSFTLPYSAYGHRMLENNCIKVSAIAREKNNPKDTYLTEKNIILHTPNLSITVSGSPLLD-SEMTATVQFENPLSSTLQNCSISLSGSGLLKSTEKSSTVQLGPGQRIRLQVSFTPYRLGLKKLMATFNSATFKDVQASVDVDVRSA-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VLU2-1", "uniprot_id": "Q9VLU2_DROME", "id": "Q9VLU2-1", "name": "protein-glutamine gamma-glutamyltransferase", "aln": "MGQKLSCCQKCGDWKWCTSKDNEESTLRIRNANANYFTGIPQGDKTDGASSAVLGVLKVDLCLEDNHEEHHTSHFYAAAAKEALVVRRGEPFRLKIHFNRDYSPSKDAISFIFTVADDTKPSPGHGTLNALVPHDGIDYLGDTLEWGAGIESHEGQTLTVLIKPPSTCPVTEWKLDIDTKLLGDGSRSYPLPLPIYVLFNPWCPDDQVYLEDRDQRKEYVMHDTTLIWRGSYNRLRPSVWKIGQFERHVLECSLKVLG------TVGRIPPAYRGDPVRVARALSALVNSVDDDGVLLGNWSEDFSGGVAPTKWTGSVEILQQFYKTQKS-VKFAQCWNFSGVLTTIARSLGIPSRIITCYSSAHDTQASLTVDVFIDANNKKLDAETTDSIWNYHVWNELWMQRPDLGVGEHGTFDGWQVVDATPQEASDNMYRVGPASVAAVKNGDILRPFDGGFVFAEVNADKLYWRYNGPSQPLKLLRKDTLAIGHLISTKAVLKWEREDITDTYKHAERSEEERSTMLKALKQSRHAFS---------------------------RYYLNDNFNDIEFDMELKDDIKIGQSFSVVLKVSNKSESRT----HMATGQISCDAVLYTGVGAVEVKTLGFELELEPKSSDYVRMEVIFEEYYDKLSSQAAFQISAAA-KVKDTDYDYYAQDDFRVRKPDIKFQLGEAAIVAQKELDVILRLENPLPIPLHKGVFTVEGPGIEQP-LKFKIAEIPVGGTAAATFKYTPPYAGRGTMLAKFTSKELDDVDGYRHYEIEPRPEDLLQPNGSHRSSNIIRRRTDVIA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* * *** * :***: * : : . : :. .. .. * : * : : : *. . : .: : : : :*****. * *:* .. :**:: : .:::* : . *. **** .::: .:.:* : * . : * :.*::*. :* **: *:* .: * * .* .** **::: . *::.*** *:.*: *: *.**:. *::: : *.*:.: .* :* : . . *.:**:*** * *: * ** :.****:*.***: *.. : ***.* *: :*. .* *.:: **** : * . : : :: :*. :*** : . .* .:* **: * * :** . :* .: : : * .. . * ... : : . : * . : :. * . : : : ::. . . . : : : : : . : : : . *.* : . : :.*.*: . : .. * * : . : * . ::.. : ", "identical_positions": 118, "similar_positions": 188, "identity": "14.46%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120720-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZTN8-1", "uniprot_id": "D3ZTN8_RAT", "id": "D3ZTN8-1", "name": "", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGCRHSRHS---------------------------------------------------------------------------------RGKRAEKVE-ETQTELLETLDKEGRILEGRHEETGQVQQTSNAQEK----------DALSDCVLEAKASLQNTCAIHVPPQEARQAKMN----------------KVDGSILSRLYRNHIQDYGSPG------PFWEQELESLHHVIEMKNERIHELEKQLFLLEMLVAATRAVLGASSLAPQEGWQPSHCRQRLRKEKEKNLILALKNTTLQQEVEDLQFQARNRLAMSRQLRKDLLQD---LEKESQNGHCCNRRRSH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TCJ8-1", "uniprot_id": "CCD69_MOUSE", "id": "Q3TCJ8-1", "name": "Coiled-coil domain-containing protein 69", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGCRQSRHS---------------------------------------------------------------------------------RGKRAEKVE-ETQTELLEALDKEGRILEGRHEEAGQVPQTSNAQEK----------VSLSDCIQEAKASLQNTCASHVSPQEATQAKMN----------------KVDGSILSRLYRNHIQDYGSPG------PFWEQELESLHHVIEMKNERIHELEKQLFLLEML-------------------------------KEKNLILALKNTTLRQEVEDLQFQAGNRLTMSRQLRKDLLQD---LEKESQNGHCCSRRRSH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NI79-1", "uniprot_id": "CCD69_HUMAN", "id": "A6NI79-1", "name": "Coiled-coil domain-containing protein 69", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGCRHSRLSSCKPPKKKRQEPEPEQPPRPEPHELGPLNGDTAITVQLCASEEAERHQKDITRILQQHEEE--------------------KKKWAQQVEKERELELRDRLDEQQRVLEGKNEEALQVLRASYEQEK----------EALTHSFREASSTQQETIDRLTSQLEAFQAKMK----------------RVEESILSRNYKKHIQDYGSPS------QFWEQELESLHFVIEMKNERIHELDRRLILMETV-------------------------------KEKNLILEEKITTLQQENEDLHVRSRNQVVLSRQLSEDLLLTREALEKEVQLRRQLQQEKEELLYRVLG-ANASP-----------------------------AFPLAPVTPTEVSFLAT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A7MC22-1", "uniprot_id": "CCD69_DANRE", "id": "A7MC22-1", "name": "Coiled-coil domain-containing protein 69", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MGCHNSKVCGQVSKKKKKNKAQEGEKRTKDIKLQDGRGTHSSEEERCCLENQLENYEWQLKILHAVLTASGDQEREQLLKDHPGDICT-LVHSITEKVKTEISADLNDLHEQQMRSVSEQHQSETEELQRLHSEEK----------NVLNESHAAAEEALKDQIEDLTSELKLFNELKR----------------RAEASTLKRDLQRNIETHGSPG------EFWEQEQESLLFVIEMKRQNLQDQGNKLLQMEAQ-------------------------------VEKNLSLEDQLLQALQQNEDFRVRIENYQSLIQQLSKEQNDMQEVLEKQSLQNQKLIQEKEELLFKLLHRRDSCS-----------------------------TFHLPSVIPTQVSPS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQM0-1", "uniprot_id": "Q9VQM0_DROME", "id": "Q9VQM0-1", "name": "", "aln": "MAKDPATTRIPRLDGVSRLPKPSTFGLASSSGSTTNRTTTTTTSTTQHIRPPTSAPKATQIFRAPGDPAKPRPASSYAPSSAALRDLGSSLKKSASGERINNAVSLLSKRTTTVLKKYFSPKSSASANAVMSSPCDMTSSLPVTPLPVGKRGMVANDQLTSSTPMPLLRSETFVCEDEKQSNRMKLESTRLSTFGRTMDIESPVPNETKVLIRDGTRIMKGSPSTDITQIVRPTQKTPLMTFCSLDTTHEMTVCSRNNATHSVNSSGIMGRTMPVIPAKDATRTISANSSGLGNLTKVVRGVGNINQTLEAAGNITKTFRGAGDLTRTVEKEANIGKTFEVAANCTQTFTRGVNLTRTMNDKNEEVSRTIDKGRSTTKTIEVGQNLTITMDAASNLTKSIDRGATLTNRGANLTKSVIEPGDFTKVIHQGANLTLSMDQLPLLEHISMPSGLDILSSKCSGNVERPSQETDDTLDVTLTSLAPDKTNMKLPLNSTLNTERLLDISALQSPRHIQLLNLTQELERGTPSRVHLQSGRRSMPQHSLLCLSPQSATTTPHGMRMMGQATPQPVHLLSPLLKQAQSALVLPTRTPDGDITMDGNGALDSTLTSTSVRGRTRYSFGLDLPDTTLDCSIELVDNSFSSSTQLQQLQQQLLKKQSSFDLDESLGILTPDQMKDFLDSPHNNLMHNLEMIRMHHPNLLQLRMEQTPSPEELPLDPIEIKSEIVKQVEASQNQVNTSQHSKLSNSFITSVTSVTSLDTGYQGDGEMSRPASRGACDHSPSNGPHLGRVSRQPSFPPPNPAPLRRQDPMTDSDFFTESDADDVLHRGDRRAQVIDGQLYGPDMMQPSASVPQMEDSCMESSGIFTDVENRCDEEMRQPELEFDVDMDMSPDDSSQTMRKGQGQPISTQQQQNQLAPQQRPPSSCLSSSSAATTLSQSLSNRTSYCSVDGGSARSFCGDEAFAAGRSTTTTAAAAAAAALSVQKTTSPRPHASLSSLCTVENFRGSVSSNSSIASPKSCKSSVTKTSAGKSRVLKSPKSPKSPKSPLNRKAHTPNKWDAVMNKIASNKSLIKTNYNDVKSKVSTTRIMTPASGSSPVSGSGSGSVSRTASSPRASPSVSASARRSPSATPKVPPKMLLAKRPSSSSGKVNATPSPPPHATPPTRQPLDKGSVGAGSVGGGGARAVKTPKSPTSPTTPTTPTSPPAKRLQTSLVSRGRSYSKDSHKSSHTDLSLMCNASSSRPSNSASGSGSPKLLANTQLRAAKKRDVRNLSISPTDLGPPPKTQQTTKGQSTRSKSSATPTPTPTSIHKRLNGTLASTAAIATPIKGVATKSGATNKLQQSAKTKSTASIKSPAIVGVSEESLRSGVDQTELQELNNGQSATGCPTPPMARDSKRTSIGNELPCETEAKLKRCEDQQDPQASTTASPLPMINPQEQEASGQVKEATITTANEPNALSLPDEISNSVSSTTMLATPRVDIAAQYPVLKPFTENGELDCARLAKFFQDTQFERKEEQRQILGLSVMVQFMSKELDAVACKENKHQCARTKGTLEKTILLLQHTQKDCERLREDLEDKGLEWIQRQQEKEYLHRTELKQAEEKLMEVQLRAKLKFCELESQLRAKDEESKQAQEAYRMEVSHKLALKQEHLRTAEQKIQELQTRLQQVETEEQGHREELIRKENIHTARLAEANQREQDLIDRVKSLTKELNTLKANKEHNERDLRDRLALSQDEISVLRTSSQRRSPCTSLPDNASAELNRLTSEADSLRCVLELKQAEISALSKAKADLIHE-------------------------------SEERLKLSNRVALLEAQNEMLRTELEAKTEKEKEIQQKMEELQKAYKYESIKRTRLTYDKEELQYHLKQRSLQLQSAESKLQDLSTGSHDNSLSSHSRCSLGRSGLEIAVTTSSPTSPVMKGMIERNDSVSWTLEIEDESFKGNTSKIVRRAGSLRSNNERCPIQRRQTLTSNGHSNGSATNGGSSPAHPNPLSQSMSATALLRSSSNSGESEGRPLSRARSKSMCIKASATSSAVCESSGQRKKPQDELSLADWPEDIPLCSSSPQAPGIEMRPRSSTMKLMSSEAKKFQEIQESAGEAMVSGANSEDESCSASSEDIMRSSSASSTASGGSLSKRPKQPPSRMSIEEALPCTPMEVSWSEDAADANGLA", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.*:..: . :::. . ::. * . : :. : :*: . *. :: . : : : : * * :.. . *. .* :** *:*:*. .: . : *:.* * : : * :: . ::: :. : : :.. ", "identical_positions": 17, "similar_positions": 62, "identity": "0.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120724-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BJS8-1", "uniprot_id": "MTBP_MOUSE", "id": "Q8BJS8-1", "name": "Mdm2-binding protein", "aln": "MDRYLLLVTWREGKFRSVAGGEIEPGTEATSLESTDKQPDLTATNIYHLLKRSISDSIHPDDSTFPACSVGGTPHSRKWFFAVQAICGFYQFCSSDWQEIHFDAEKDKIEDVLQANIEECQSAVECFEEDDSNSRESLPLADLYEESAENLHQLSDKLPAPGRAMIDIILLPSDKDPPKLKECLPIVGALKHLKEWHSAKVIIAGSYCEINCQKIAEYLSASVVPLEEFRNAIDPRELWRGEIQMRERKFGFEISFPEFCLKGVTPTNVSAYNLNTCFLAKKIASS-------KVFHYYGPALEFVQMIKLSDLPSCYMSDIEFELEVTGHCTRQNSMLLLEQISSLCGKVGALFVLPCTVSNVLIPPPSQLASRKWKEYMAKKPKTISVPDVAVKGEFSGYHLLLQGMGKRKCRATLLHSASQINGSFALSVIHGKMKTKAGEARPSFPFDFS-SLPRFSEEQVLQREKQLASFQVLALKECLKRRKAANQPEAFSADELKSLLALTRERFLGHFDVLPTEAALAQTDTVKAAGVVNDDGTVEPYSSSLMETNPLEWPERHVLQNLETSEKAKQKMRTGSLPR-SSEQLLGHKEGPRDSLTLLDAKELLKYFTSDGLPVGDLQPLHIQRGEKPFVLTPELSPGKLQVLPFEKASECHYHGIEYCLDDQKALERDGGFSELQSRLIRYETQTTCTRDSFPVPTVLSPLPSPAVLSEPQSVPEGEALQGELRTEVSGLKRRSKDPSCLYPQKRLTRSESSDCLPSQASCNSNHHHHTGKPRKPQAERCVSG----LPLPGREASKDTSKTSSGQKRAHESKSSKQMKESRSQKHTRMLKEVVKDTLKRHHITEAHESFTACSQRLFDISKFYLKDLKTSRGLFEEMKKTANNNVVQVIEWVVEKMSKK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96DY7-1", "uniprot_id": "MTBP_HUMAN", "id": "Q96DY7-1", "name": "Mdm2-binding protein", "aln": "MDRYLLLVIWGEGKFPSAASREAEHGPEVSSGEGTENQPDFTAANVYHLLKRSISASINPEDSTFPACSVGGIPGSKKWFFAVQAIYGFYQFCSSDWQEIHFDTEKDKIEDVLQTNIEECLGAVECFEEEDSNSRESLSLADLYEEAAENLHQLSDKLPAPGRAMVDIILLLSDKDPPKLKDYLPTVGALKHLREWYSAKITIAGNHCEINCQKIAEYLSANVVSLEDLRNVIDSKELWRGKIQIWERKFGFEISFPEFCLKGVTLKNFSTSNLNTDFLAKKIIPSKDKNILPKVFHYYGPALEFVQMIKLSDLPSCYMSDIEFELGLT-NSTKQNSVLLLEQISSLCSKVGALFVLPCTISNILIPPPNQLSSRKWKEYIAKKPKTISVPDVEVKGECSSYYLLLQGNGNRRCKATLIHSANQINGSFALNLIHGKMKTKTEEAKLSFPFDLL-SLPHFSGEQIVQREKQLANVQVLALEECLKRRKLAKQPETVSVAELKSLLVLTRKHFLDYFDAVIPKMILRKMDKIKTFNILNDFSPVEPNSSSLMETNPLEWPERHVLQNLETFEKTKQKMRTGSLPH-SSEQLLGHKEGPRDSITLLDAKELLKYFTSDGLPIGDLQPLPIQKGEKTFVLTPELSPGKLQVLPFEKASVCHYHGIEYCLDDRKALERDGGFSELQSRLIRYETQTTCTRESFPVPTVLSPLPSPVVSSDPGSVPDGEVLQNELRTEVSRLKRRSKDLNCLYPRKRLVKSESSESLLSQTTGNSNHYHHHVTSRKPQTERSLPVTCPLVPIPSCETPKLATKTSSGQKSMHESKTSRQIKESRSQKHTRILKEVVTETLKKHSITETHECFTACSQRLFEISKFYLKDLKTSRGLFEEMKKTANNNAVQVIDWVLEKTSKK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5K2-1", "uniprot_id": "A0ACD6B5K2_DANRE", "id": "A0ACD6B5K2-1", "name": "", "aln": "MDRYVLAVIIN---------LEAKKDSSFNGVDETKK--------VFDNLKK-ISGSNLTRIPPFPACSPSGSPASQRWYFAIQVSYGVTQWCSSEWDEVCS--QRSDSEESEASALENCISALQEQEEQ-SSLTENPSHAELFEEAAEGLHQLADKLPPPGKSLLDVIVLCVDEEVG-LKDMLPVIGSLKHMRAWHSAQMIMVTEHSAG-WQKAAMYLDARLCSPSVIDSCVDGTEIWRGGLNIREKKFVSELKFEGFCLR-AQRRNHWTDALYPHSDPQSQTDHK---LQHEVFQCYQPVLELIQLVKVTDLPILLHSSTAFELGLVSKSVKAK--LLLDQLCTLRGEVGALFSLSCVISTETFPAASQLSSCKWRDFMSKRPKDIPVPDMEVKGERGHYLFLVQGAESGGCTARMIHTANQINGAAALSTLNALIREKASSSSGSSTADWLRSLPCLRREQFVHRERKLAKVQTLVLKECCRRREDAQKSAAIPVNELKALLNLAREQYLQMHDSTLPRASEHMCLQKKKQPTSSKKNEIKHSHS--------EWPERSVLQNYENIQRVRQRSRCRLFSSGSSESLMGPKDSQRGTSTLLDARELLKHFTPDGLPSGELQPLPVLRGEHAFQLSPDLTPRKVTKLPFLKAARSNYHGIEFCLDERKALERDRGFVRLQSRLIRYETQSTCCKEPCPVPFALSPAPSPAVLSEPGSVPDGEALHSEP----SRLKRRSRE-TDLQPHKRFCKSESSE------SVGSAGAHPAVEALRQQSAHSGST--------------LARRSASVTDPSPSQKPNQTHTESRSQKHNRMLKEVVAKTLNKHGIGSEHKCFEACSKRLFDISKFYLKDLKTSRGLHEEMKKAACNNVKQVIDWVVEKSSKR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "****:* * * : ... .. : *.: ::. **: ** * . ..***** .* * *::*:**:*. *. *:***:*:*: ::.. *: : :*:* .*:: **: *. *. . *:*:**:**.****:****.**::::*:*:* *:: **: ** :*:***:: *:**:: :. .:. ** * **.* : . . : . :* *:*** ::: *:** *:.* ***: . * : * . .:. :**: * *.**::*::*::*** *. *** :. :..: : ***:*:.:* .:***** *.*.:*. :*...**:* **:::::*:** *.***: **** . * :*:** . * * ::*:*.****: **. ::. :: *: .: * . * *** : **.::**::**..*.*.*:** :**: *::. :... ***:** *:*:::* .* .. * .. . :: * ***** **** *. ::.:*: * :. ***.*:* *:. *.: *****:****:**.**** *:**** : :**:.* *:*:*:* *: *** **: .:*****:***::****** ** .***********:** ::. *** .*** ***.* *:* ***:**.*:.* * *****:: . * *:**: :****: : .* * . : *: :. . : :::* . ..*..: .*******.*:***** .**::* * . *:.* ***:***:***************.*****:* **. ***:**:** **:", "identical_positions": 358, "similar_positions": 269, "identity": "39.47%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120727-10", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3U132-1", "uniprot_id": "TESP1_MOUSE", "id": "Q3U132-1", "name": "Protein TESPA1", "aln": "MEASVLSPTSWEKRRAWLRQSRNWQTQVLEEEAAAALQDALDPEPSSLDDVFQEGNPINKIEDWLQGCGCRDTEEGLSEESGQSNYSGYSSHGTSFEDDLSLGAEATLLSTNGNLFSRNFLQTPRLCQLLDLGSSLASSSMTGGTNKTSSSISEILDQVQEDAEDILFSLGFGHENHKDTSRIPARFFSNPSQAKGINFQLFLKSQVQRMEMEDPCLMLASRFKQVQTLAVTADAFFCLYSYVSKTPVQKFTPSNMFWNFD-PTDVPSIRILAPEPEPYSPRERLRRAISKMCLYTGSRDRLSSSYNNPKKNSLDQIVWEVMDRVKGEK--IQQDP-----------------EHRQALGEESVPPIQNTNPSTSSLPCVSYP--------KEETQGDM-----------------CHAHALARPGPQYHINSTQVRRQLWVLQDINEKPRSAENESPWERKSKARKN--------------------------------------LFQRVPVDKNIKSLNLPTIQQKQNQGQARHELTNL----------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A2RU30-1", "uniprot_id": "TESP1_HUMAN", "id": "A2RU30-1", "name": "Protein TESPA1", "aln": "MEASVLSPTSWEKRRAWLRQSRNWQTQVLEEEAAAALQDVPDPEPSSLDDVFQEGNPINKIEDWLQDCGY--SEEGFSEEAGQFIYNGFCSHGTSFEDDLTLGAEATLLAANGKLFSRSFLETARPCQLLDLGCSLASSSMTGGTNKTSSSISEILDKVQEDAEDVLFSLGFGQEDHKDTSRIPARFFTTPSQAKGIDFQLFLKSQVRRIEMEDPCLMLASRFKQVQTLAVTADAFFCLYSYVSKTPVQKFTPSHMFWNCNHPTDVPSIRILSREPEPQSPRDRLRKAISKMCLYTCPRDRPPPPHNTPKRNSLDQVVLEVMDKVKEEKQFLQQDS-----------------DLGQFSQEDPVPPAEGKKLPTSPYPCVFCC--------EEETQQRMSTVLAPSQTLDSNPKVPCCTHSLPIEDPQWSTDPAQIRRELCSLPATNTETHPAKDETFWKRKSRARKS--------------------------------------LFQKNLMGRKVKSLDLSITQQKWKQSVDRPELRRSLSQQPQDTFDLEEVQSNSEEEQSQSRWPSRPRHPHHHQTFAGKDS-------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F8S9-1", "uniprot_id": "E7F8S9_DANRE", "id": "E7F8S9-1", "name": "", "aln": "----MESPSKIERRQAWALSSRRKFTVRDGEHRSPTADDQ--PHFSLQDDVFVDGCSAGKIESWLQGCGS------EASPAKSIHLAGSLRTGVSFEDDLILGAEATGLYASSSAQQFSTPQQKLNLPLYSMGQSVASSAFSTTTARTASSLSEVLQMRAEDAEETLFQLGFGCEEPQVTARIPVRFFNFPSQLRGINFRLFLESQLSRIRQEDPCLSLASRFRQVEALTAMANAFYSLYSHVSRTPLQKLAPPQLTFTSPIVERSRSRNSVR--SEPRSPVERLKDTISKMCLYTGSRGSDSTPPNNSPRKRKSSLSGVVEKSAENNNDDTEQDLCLQMEVDYLDQNLDWFIDSRTELNNRTCEENTERTDYSEPIPCESLSGMTSENVHKHRHRLEECTPCLEPKTDMDKKSKGCNVDSVHMNRSRVNVEPVPIITHDIICPQVVEYVKQAPYRCMYTNNVDAKDSHQAHQATNTPSVRQSNSMNVPKSLCQITITGWEDDTTFLNTQEQCSANINSYLTPVKPPNLNKQGNSFELEEVHSAEEEEATSSEFCSAVTLSVSPQHNKSLPLRGDSFQSDSSGYVEEEAQQSHSSLEKT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : **:. *:*:** .**. * *. :.: :* *. * **** :* . .***.***.** :. : . * *.****** ****** * :... . . : * .:* *:***::: * :*:**:**:*: ****: **.**** *: : *:***.***. *** :**:*:***:**: *:. ***** *****:**::*:. *:**:.***:**:**:**::*.:: :. * . : .** ** :**: :******** .*. ... *.. :: ..: * . .: :: :** : : . . :.. ** :.. : * ..:: .: :.. : . : * . : .: *:.. * : . :::* . : :: ** . ", "identical_positions": 139, "similar_positions": 137, "identity": "23.21%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120727-11", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q810J1-1", "uniprot_id": "PSG22_MOUSE", "id": "Q810J1-1", "name": "Pregnancy-specific glycoprotein 22", "aln": "MEVSSELLS-NGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRG-VTDMSLGIALYSLDYSTSVTGPKHSGRETLYRN---GSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGR---EIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E9Q6J6-1", "uniprot_id": "E9Q6J6_MOUSE", "id": "E9Q6J6-1", "name": "", "aln": "MEVSSELLLSNGCTSRQRVLLTASLFTCWLLSTTAKVTIHS-PLQVVEGQNVFLRVDNLPEDLLAFAWYRG-LRNWRVAIALHLVEYNASMTGPEHSDREILHSN---GSLWIQNVTQEDTGYYTLQTISKHGKLVSNTSTFLQVYSALFTCGRPTSPAKLTIESVPPRVAEGGSVLLLVHNLPEYSQLFSWYKGLTLFNEVEIAEYKIAKNLSDPGPAHSGR---EIVFSNGSLLLQNVTWKDTGFYTLQTVNGFREMELAHIYLRVDT---PCCDPPDSARLRIDPVTCHAAEGGSVLLQVHNLPEDVQTFSWYKGVDSTPYFRIVEYSKAMKSIFSGYAHSRRETGYTNGSLLLQDVTEKDTGFYTLLTIDSHVKVETVHAQVNVHKLVTQPVVRVTDSTVRVQSSVVFTCFSDNTGVSIRWLFNNQSLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVSLAVMNE-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q61400-1", "uniprot_id": "CEAMA_MOUSE", "id": "Q61400-1", "name": "Cell adhesion molecule CEACAM10", "aln": "MELASAHLH-KGQVPWVGLLLTASLLTYWSPATTAQVTVEAVPPNVTADNNVLLLVHNLPQTLRVFYWYKGNSGAGHNEIGRFVTSINRSKMGLAHSGRETIYSN---GSLFFQSVTKNDEGVYTLYMLDQNFEITP-ISVRFHVHPSLLPSLSPPTTGQVTVEAVPPNVAEGENVLLLVHNLPRTLRAIYWYRGTTAGERNEIARFITASNKIILGPAHSDR---EIIYNNGSLFFQGVTKNDEGAYALDML------------------------------------------------------------------------------------FQNFDH-------------------------TLMPVQFNVHAKKQ------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AC58IGG2-1", "uniprot_id": "A0AC58IGG2_DANRE", "id": "A0AC58IGG2-1", "name": "", "aln": "----------------MKVLFSLFLLLFLTLHENGVSGVGKDDVSVSRGDSVTLHTGVKTNQQYIIVWLYEGIRIAVIRGDLSYICTDVQCNNGTERFRDRLKLDHLTGSLTVMNTRLRDAGEYQLLISSS--KSINEMIFRVVVKDVYWVDEDDN-------DEESVSVIEGDSVTLHTGVKTDQQDRIVWFNEGSRVAVISGDLNVICTDVQCDNSTTRFKNRLNLDHQTGSLTIMNSRNTDAGEYQLLIFSSFRLSKKIFRVVVHDVH-----------WVQEVKVEVSVTDGYSVTLNTDTTTKQLHKIKWYFN------------NICVAQIRGDLSYICTDVQCDEGAERFGDRLKLDHQTGSLTIMNIRNRDRGEYKLEIISNRGSRRKIFRVLVDDSGPFSAAVPRLYEIVAIAAAVLLLAAAVSGVICCYKSKANGKNSRRQRSDQAKGVEDCPDQNDTLLMKTISNSSTNQTEAAIETPT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:: *: .. : .: .:.* * . .: : * . . . . *: : : *** . .. .* * * * .. : . * : . * ** .* * . . : *:. : . .: ..: : :: ...*** : . * * * * . . : :* :: . : . ", "identical_positions": 28, "similar_positions": 63, "identity": "5.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120727-13", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L1E9-1", "uniprot_id": "A0ABK0L1E9_RAT", "id": "A0ABK0L1E9-1", "name": "", "aln": "MIEDKGPRVTDYFVVAGLTDTSTLLDQEINRIDTNK-SIGPKAPITDIAVIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYRRGRDKPPLTDIGVLYEGKERLIPGCEVIQATPYGRCANVNNSSTTSQRIFITYRRAPPVRSQNSLAVTDICVIITSKGETPPHTFCKVDKNLNCGMWGSNVFLCYKKSVPASNAIAYKAGLIFRYPEEDYESFPLSES--VPLFCLPMGATIECWDPQTKYP-----LPVFSTFVLTGSS-AEKVYGAAIQFYEPYSRDLLTEKQLSQLGLLTPVERKVVS-KPINSNKCICLLSHWPFFEAFKKFLMFIYKVSVSGP-HPLPIEKHISHFMQNIPFPSPQRPRILVQLSVHDALILSQPVSTPLPLSGANFSSLLMNLGPENCATLLLLVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAGVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLDTNTLYVADEKKNTNWKQLPKKPCKSLLGTLRKLYLQLCSVHRKPQESSAIEMTPIEADFSWQKKMTQLEMEIQETFLRFMASVLKGYRSYLRPITEAPSNKATAADSLFDRQGFLKSRDRAYTKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFP-DKGVEKTDKVDLDSAEDTKLIELDDSQKSEHTVFITPPEPPPDDGSDLSP-----QYSYTYFPRLDLKLFDSPQEPKLRFSRHPPGSGITNSPALMAKRTKQEIKTAHKLAKRCYTNPPQWAKYLFSHCYSLWFICLPAYVRVSHPK---VRALQQAHDVLVKMRKTDVDPLDEVCYRVVMQLCGLWVHPVLAVRVLFEMKTARIKPNAITYGYYNKVVLESPWP-SSTRSGIFLWTKVRNVVHGLAQFRQPLKKTGQKS--QVFSISAPQNAACGSDGDTVSHGSVDSSNDANNGEHTVFVKDLISLDSIDNHSSTGGQSDQGYGSKDELVKEDADIHASEEHMPQELTA-TELHIEEESDLSTIVPKHSQPTPEPQSPTEPPAWGSSIVK----VPSGLFDTNNRTSSTGSSSNALFSTQAP-------VEDAVFGEATNFKKSGDRGEKRQKHFPERSCSFSSESRAGMLLKKSSLDLNSSEMAIMMGADAKILTAALTCPKTSPLHVARTHSFENVNCHLADNRTRVSEGIWDSEHRSSPVLEMLEESQELLEPVVGDTVAETAVEMSFNNVQSNSNSNQSRDTKAGSQDTVNKRSSSYTTGKAIEREDVETGLDPLSLLATECV-EKTSDSED--KLFSPVISRNLADEIESYMNLKSPLGSKSSSMELHGEGNQEPG---SPALFTHPLERRSSLPS-----AQDSTEIEKSPPAVSRSKTLTGRFKPQTPYRTYKDRSTSLSALVRSSPNSSLGSVVN-SLSGLKLDNILSGPKIDVLKSSMKQAATVASKMWVAVASAYSYSDDEEEPNK-DYSFPAGLEDHHILGESLSPTTSISGLVP----SELTQSSTSLGSSSSSGDVGKSQCPTGEVPFSRNIKGQDFEKSDHGSSQNTSMSSIYQNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTTCPFCKSNFLPLLNVEFKDLRGSASFFLKPSTSGDSLQSGSIPSANEPLEHKPVSSSAEP-DLISFMDYSKHSETITEEASYTVESSDEIKKTS-DVQSVKMSSVPNSLSKRNVSLTRSHSVGGPLQNIDVSQRPFHGISTVSLPNSLQEDVDHLG-KRPNPPPVSVPYLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLILTSEHCNEGVQLPLSSLSQDSKLVYIQLLWDNINLHQEP-GEPLYVSWRN--LNSEKKLSLLSEEQQAASALVETIRQSIQQNDVLKPINLLSQQMK----PDTKRQRSLYREILFLSLVSLGRENIDIEAFDNEYGLAYRSLSS-EILEKLQKIDAPPSISVEWCRKCFGAPLI-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A6H8H2-1", "uniprot_id": "DEN4C_MOUSE", "id": "A6H8H2-1", "name": "DENN domain-containing protein 4C", "aln": "MIEDKGPRVTDYFVVAGLTDTSTLLDQEINRTDTN--SIGPKAPITDIAVIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYRRGRDKPPLTDIGVLYEGKERLMPGCEVIQATPYGRCANVNNSSTTSQRIFITYRRAPPVRSQNSLAVTDICVIITSKGETPPHTFCKVDKNLNCGMWGSNVFLCYKKSVPASNAIAYKAGLIFRYPEEDYESFPLSPS--VPLFCLPMGATIECWDPQIKYP-----LPVFSTFVLTGSS-AEKVYGAAIQFYEPYSQERLTEKQLTQLGLLTLVEKRVVS-KPINSNKCICLLSHWPFFEAFKNFLMFIYKVSVSGP-HPLPIEKHISHFMQNIPFPSPQRPRILIQLSVHDAFILSQPVSTPLPLSGANFSSLLMNLGPENCATLLLLVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAGVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLDTNTLYVADERKNINWKQLPKRPCKSLLGTLRRLYQQLCSVHRKPQESSAIEMTPIEADYSWQKKMTQLEMEIQETFLRFMASILKGYRSYLRPITEAPSNKATAADSLFDRQGFLKSRDRAYTKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFP-DKGVERTEKVDLDSAEDTRLIELDDSQRSEHTVFIMPPEPPPDDGNNLSP-----QYSYTYFPRLDLKLFDSPQKLKLCFNRHPPGSSITNSPALMAKRTKQEIKTAHKLAKRCYTNPPQWAKYLFSHCYSLWFICLPAYVRVSHPK---VRALQQAHDVLVKMRKTDVDPLDEVCYRVVMQLCGLWVNPVLAVRVLFEMKTARIKPNAITYGYYNKVVLESPWP-SSTRSGIFLWTKVRNVVHGLAQFRQPLKKTGQKS--QVFSIS-------------------------------------------------GGQSDQGYGSKDELVKEGADGHAPEEHTPPELTT-TELHIEEECDISAIVSKHLQPTPEPQSPTEPPAWGSSIVK----VPSGLFDTNNRTS-TGSTSTVLFSTQAP-------VEDAVFSEVTNFKKNGDRGEKKQKHFPERSCSFSSESRAGMLLKKSSLDLNSSEMAIMMGADAKILTAALTCPKTSPPHVTRTHSFENVNCHLADSRTRMSEGTRDSEHRSSPVLEMLEESQELLEPVVGDNVAETAAEMTCNSLQSNSHSDQSRDTQAGAQDPVNKRSSSYATRKAIEREDVETGLDPLSLLATECV-EKTSDSED--KLFSPVISRNLADEIESYMNLKSPLGSKSCSMELHGEGNQEPG---SPAVFAHPLERSSSLPSDRGPPARDSTETEKSSPAVSSSKTLTGRFKPQSPYRAYKDRSTSLSALVRSSPNSSLGSVVN-SLSGLKLDNILSGPKIDVLKSSMKQAATVASKMWVAVASAYSYSDDEEETNK-DYSFPAGLEDHHIVGETLSPNTSVSGLVP----SELTQSNTSLGSSSSSGDVGKLQCPAGEVPFSRNIKGQDFEKSDHGSSQNTSMSSIYQNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTTCPFCKSNFLPLLNVEFKDLRGSASFFLKPSTSGDSLQSGSIPSASEPSEHKPTSSSAEP-DLISFMDFSKHSETITEEASYTVESSDEIKKTNGDVQSVKMSSVPNSLSKRNVSLTRSHSVGGPLQNIDFSQRPFHGVSTVSLPSSLQEDVDHLG-KRPSPPPVSVPYLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLILTSEHCNGGVQLPLSSLSQDSKLVYIQLLWDNINLHQEP-GEPLYVSWRN--LNSEKKPSLLSEQQQAASALVETIRQSIQQNDVLKPINLLSQQMK----PGTKRQRSLYREILFLSLVSLGRENIDIEAFDNEYGLAYRSLPS-ESLERLQRIDAPPSISVEWCRKCFGAPLI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5VZ89-1", "uniprot_id": "DEN4C_HUMAN", "id": "Q5VZ89-1", "name": "DENN domain-containing protein 4C", "aln": "MIEDKGPRVTDYFVVAGLTDTSTLLDQEINRLDTK--STGPKAPITDIAIIIKSAGETVPEGYTCVEATPSALQANLNYGSLKSPELFLCYKRGRDKPPLTDIGVLYEGKERLIPGCEVILATPYGRCANVNNSSTTSQRIFITYRRAPPVRPQNSLAVTDICVIVTSKGETPPHTFCKVDKNLNCGMWGSSVFLCYKKSVPASNAIAYKAGLIFRYPEEDYESFPLSESD-VPLFCLPMGATIECWDPETKYP-----LPVFSTFVLTGSS-AKKVYGAAIQFYEPYSRELLSEKQLMHLGLLTPVERKMVS-KSINTNKCICLLSHWPFFEAFRKFLMFIYKLSVSGP-HPLPIEKHISHFMQNIPFPSPQRPRILVQLSVHDALILSQPVSTPLPLSGANFSTLLMNLGPENCATLLLFVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAAVLSAPLPFIVGVDSRYFDLHDPPQDVVCIDLDTNMLYVSDEKKNMNWKQLPKKPCKNLLSTLKKLYPQLSSVHQKTQEGSAIDMTPIEADFSWQKKMTQLEMEIQEAFLRFMASILKGYRTYLRPITEAPSNKATAADSLFDRQGFLKSRDRAYAKFYTLLSKTQIFIRFIEECSFVSDKDTGLAFFDDCIEKLFP-DKGTEKTDKVDFDSAEDTRLIELDDSQKSEHTVFIMPPEPPPDDGKDLSP-----KYSYKYFPRLDLKLFDRPQELKLCFSRHPTGNSITKSPPLMAKRTKQEIKTAHKLAKRCYTNPPQWAKCLFSHCYSLWFICLPAYVRVSHPK---VRALQQAYDVLIKMRKTDVDPLDEVCYRVVMQLCGLWGHPVLAVRVLFEMKTARIKPNAITYGYYNKVVLESPWP-SSTRSGIFLWTKVRNVVRGLAQFRQPLKKTVQRS--QVSSIS-------------------------------------------------GGQSDQGYGSKDELIKDDAEIHVPEEQAARELITKTKMQTEEVCDASAIVAKHSQPSPEPHSPTEPPAWGSSIVK----VPSGIFDVNSRKSSTGSISNVLFSTQDP-------VEDAVFGEATNLKKNGDRGEKRQKHFPERSCSFSSESRAGMLLKKSSLDSNSSEMAIMMGADAKILTAALTCPKTSLLHIARTHSFENVSCHLPDSRTCMSESTWNPEHRSSPVPEMLEESQELLEPVVDDVPKTTATVDTYESLLSDSNSNQSRDLKTVSKDLRNKRSSLYGIAKVVQREDVETGLDPLSLLATECTGGKTPDSED--KLFSPVIARNLADEIESYMNLKSPLGSKSSSMELHREENRESG---MTTAFIHALERRSSLPLDHGSPAQENPESEKSSPAVSRSKTFTGRFKQQTPSRTHKERSTSLSALVRSSPHGSLGSVVN-SLSGLKLDNILSGPKIDVLKSGMKQAATVASKMWVAVASAYSYSDDEEETNR-DYSFPAGLED-HILGENISPNTSISGLVP----SELTQSNTSLGSSSSSGDVGKLHYPTGEVPFPRGMKGQDFEKSDHGSSQNTSMSSIYQNCAMEVLMSSCSQCRACGALVYDEEIMAGWTADDSNLNTACPFCKSNFLPLLNIEFKDLRGSASFFLKPSTSGDSLQSGSIPLANESLEHKPVSSLAEP-DLINFMDFPKHNQIITEETGSAVEPSDEIKRASGDVQTMKISSVPNSLSKRNVSLTRSHSVGGPLQNIDFTQRPFHGISTVSLPNSLQEVVDPLG-KRPNPPPVSVPYLSPLVLRKELESLLENEGDQVIHTSSFINQHPIIFWNLVWYFRRLDLPSNLPGLILTSEHCNEGVQLPLSSLSQDSKLVYIQLLWDNINLHQEP-REPLYVSWRN--FNSEKKSSLLSEEQQETSTLVETIRQSIQHNNVLKPINLLSQQMK----PGMKRQRSLYREILFLSLVSLGRENIDIEAFDNEYGIAYNSLSS-EILERLQKIDAPPSASVEWCRKCFGAPLI-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BE44-1", "uniprot_id": "A0A8M2BE44_DANRE", "id": "A0A8M2BE44-1", "name": "", "aln": "MIEDKGHRVTDYFVVAGLTDKSTPLEQDISEAKSS----GPKAPITDLAVINKSSGETVPEGFTCIESTYSGQPANLNHGSLKSPELFLCYKRGRGKPPLIDIGVLYEGKERLIQGCEVIEATPFGRCANVNNSSATSQRIFITYRRAPPVQPQNSLAVTDICVIITNKGETPPHTFCKVDKNLNCGMWGSSVFLCYKKSVSSSNSIAYKAGLIFRYPEEDYESFPLSES--VPLFCLPMGAKIECWAPNTRYP-----LPVFSTFVLTNSN-GEKVYGAGIQFYEPYPVDGLSEKQKIQLGLVSAVDKKVLPNRTVNTNKCICLLSRWPFFEAFRKFLMFLYKLSANGV-SPLPIEKHISHFMHNVSFPSPQRPRILVQLSAHDTLILSQPVCTPLPLSGADYSTLLMNLGPENCATLLHFVLLESKILLHSLRPAVLTGVAEAVVAMIFPFQWQCPYIPLCPLSLAGVLNAPCPFIVGVDSRYFDLYDPPPDVVCVDLDTNTIYLSDEKRHSNWKNLPKKPSKSLISFLGSLHHQLATVRRTATEGLAVEMTPIEADFTWHKKKTELEMEIQEVFLRFMASILKGYRTYLKPITQAPSEKATAADSLYDLQGFLKSRDRAHQKFYSQLTKTQIFIRFVEECTFVSDKDTGLAFFDDCIRKLFPSDKGTDKGTKVEGESSEDTRLMELDESQKSEHTVFVMPPEPPLEDGPDPPP-----KYSYKNFPSLRLELFDRPLELRPALSTRAAGSSVSSSPALLAKRTKQEIKMAYKLAKRFYSNPPQWAKCLCSHCYSLWFICLPARMRTAQSK---PRAMQQAFNVLLKMRSSEVEVLDEVCYRVVMQLCGLWEMPVMAVRVLMEMKKAGVEPNAITYGYYNKAVLESPWP-SRNRSGLFMWTKMRNLVRGVVQFKRALRGTTLQIGSSLKSTDLSASTAVGADGDRLSHGSVDG----IVEEHILFSHSILVEDVIDSHYSTAAQSDQGYGSKDELPQEHTEEPVTSPPLSTNHTCSSKETNTKNGQDIASSVDSVVAVTEPPSPAEIAPCVASIVKPSTDIPVHFDSTAGRGETAGVCTGKLFMSRKKSEDVALSVEDATVIPDSQLPQSGQ--QQRVKAFMERSCSFSAESKAGMLQKKSSLELS----ADHMGADAKILAAVFSGSQTPPPFAS-----------IAPFKEFKVEATLSPALQE----EEQEEKQETKHESFTSAAEGVEKSIKRDNAAAESNSSERVGRTTG---------SAVSSSKAVERENVEMGADPLSLFASETEDTTSIQSQESTRTFPPLVSRNLADEIEMYMSLQSPLTARSPSMELQQGSNPESINCPDSPAVKQSLERRSSLPIG-PVKVASSTEHPKPSPAVTRSKTFAVKS-PKTPG-SAGQRSSSLTALVKSSQNSSLGSVIN-SISGIKMDSLLVGPKVDMLKSGMKQAANVASKMWDAVASAYSYSDDEEDNLKPQYSFPARLEEQLLSGEGDTENTLPRGLMPSLGSNGLAHSNTSLGSSSGSSDTGQAHLSTPLTPG-RSMRGADSERSEHSSSHHASTSSIYQNCALEVLMSSCSQCRSCEALVYDEEIMAGWTADDSNLNCTCPFCQVTFLPLLHVEFQDLRATPGFYLKTSTSGDSIHSSTTQPTTSSSSEVKVSSPSDPSDLMTFAESSEDSKSPVEMP--VAQTGTPKILVPEPVHSDPLGLMERQAEKRNT-LTRSNSMGGPLQNLDLIQRPNHGISTISLPNSLQEVSDTLGQKRPNPKPVSVPYLSPLVLRKELESLLENEGDQVIYTHKFLSQHPIIFWNLVWYFRRLDLPSILPGLILTSEHCNNGVKLPQTSLSQDSKQVYVQLLWDNVNLHQEP-TEPLYQLWRT--FLQ-RKGTLAPTDHQETRSLLNSIVRSIQMNDVYGPINMLIREIKKH--PEVKRQRSVYREIMFLSLVALGRENIDIEAFNREYRLAYSQLSA-EQLKVLSPIDRPPSNGVQWCLNSFGAPVI-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W3D3-1", "uniprot_id": "CRAG_DROME", "id": "Q9W3D3-1", "name": "DENN domain-containing protein Crag", "aln": "-MEEK--RIADYFVVAGMPENPQLLQENSFNDSGRLRAATTIEPITDIGVYFPLLGEEVPEGYEILSHTPTGLQANLNHGSVRTTDCYIYFRRGKDRPPLVDIGVLYDGHERIMSDAEIVAETPGGRVANVNNS---SAKTFLTYRRARADMPCNELVVTELCVIVQSKGERAPHAFCLIYKTLNKGYVGSDVYLCYKKSMYRPKHISYKPEILLRYPTFDHTDFPLNLCPSVPLFCLPMGASLEAWPHVNGTEKRKPISPVFSTFVLTVSDGTYKVYGSALTFYEDYDESKLSAEQKELLGWDEEFG----AQHSLHMIKAICLLSHHPFGDTFDKWLKYLHRMVLYDVNIPIPVERYITQLLDEVPFPAPS-IHLQLSSESNDRILLTQPEDSPLPRSGAGFHILLQNLGTDNCLHVLLLALTEQKILIHSLRPATLTAVAEAIVSLLFPFKWQCPYIPLCPLGLAEVLHAPLPYLIGVDSRFFDLYEPPTDVTCIDLDTNNISLCESQRHLSPKLLPKRAARLLRQTLTELENAKPISYDSTN--------SLDRDIRKRKRELVLEQRIQEAFLLFMASILRGYRDFLVPISKAPSVGATDPSALFQLKAFLRSRDKSHQKFFELMMKTQMFIRFIEERSFVSDGDHGLSFFDECAEKVGN-----------YDETPAQLHLVDWDTGQNSERTKYIFPPDSVTPAGSQPGGGGGGLAYNYENFT-LQPELLQSTKKTALSKFLQLQLNASLSPGSPIARRTKHEIKLSQKMASRCQQHPEAWSKYLLATCYSLYFLILPSMVLDPRHAGKEPEILRAAYDVLVRASRLKIT-CDEFCYRIMMQLCGIHNLPVLAVRLHYLMKRSGVQANALTYGFYNRCVLESQWPQDSTTISQIRWNRIKNVVLGAAQFRKAGKQRAASKVNKSLSAS----------------------------------------------------QDQNLSTLETVDGQSRTSLASSSGDGGGHGLLDFAAFDRLRNKLGSIVRQTVTGGNNETMGDAVNNTGLLIPGELSAPNTP---------------------------------------------------------------------------------------TYGGDTEILAKALQQQQPRKQIMSIGGG--------DDDDEDEDEDEYTAGSPSTPQKQLEAGADDLEYAGGGDYEADEEDEDEVDEHVAAQRARQR-----------------VQSPTKISPRTPVTQNDPLGALNEEESAASATPTQET-----QQEQQHSQSQIDSSIYSDKPILFRGQRSATFDES----------TQIGKSMHRSETMPVASSG-VTNSLANIGSSLKFTFGRYSPARLSLKKDLKLPANIIENISSISPSLTGKKSNELIQGSLSSIKSAANSLTKKFDEIKGVISANSTPTKTNNGHHPHGLHHGHHHPHHHHHHHSQHGNAEQEEHDAAVHEEGKLRR---------VSSDLDPWGRLSESRKSSYNNLVPLGENSSTGALHMHAFPAVPDNLYSLTSENAADRDCDVLIQLTTCSQCHNCSVLVYDEEIMSGWTAEDSNLNTTCHACNKLTVPFLSVQIERQVEES----------------------------------------------------------------------------------------------------------------------EQSDPLQDGKEQIANGNSHKTSLTVPYLNPLVLRKELENILTQEGDIALIKPEFVDEHPIIYWNLLWLMERIESKTHLPELCLPVPSDKEHIDP-----LSKVKTVHIQCLWDNLSLHTEASGPPMYLLYRETQPTSPLIKALLTDQAQLNKNVIQQIISAIRCNDFATPLKRLANERHKLKSNGVERSHSFYRDILFLALTAIGRSNVDLATFHREYAAVFDKLTERECNMYYRNQDLPPSASTIFCRAYFRPLLLP", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*:* *::*******:.:.. *::: . . . ****:.: ** ****: :. * :. ****:**:::.: :: ::**:.:*** ******:*:**:: ..*:: ** ** ****** * : *:***** . . *.*.**::***: .*** .**:** : *.** * **.*:******: .: *:**. :::*** *: .***. . **********.:*.* ********* *. ****:.: *** * . *: :* ** . . :.:: *.*****: ** ::* ::* ::::: . *:*:*::*::::.::.**:*. :: :. . :* ::*:** :*** ***.: ** ***.:** :* :.* *.***:******.**.****:*:::***:***********.** ** ** *:::*****:***::** **.*:***** : :.:.::: . * ***:..: * * * .. .:: * :*: ** .***.** ****:*:*** :* **::*** ** ..:*:: :.**:***::: **: : ***:****:** :**** * **:***:* .*: ::. : :*:: * .*.**:* :: **:. * : *.* *. * :*:: . : : .. .. . :*:***:*** : *:*.* :* *:* * : ****:*: **: : .: . :: *.:**:: .: **.***::*****: **:***: ** : ::.**:***:**: **** ** . . . : *.:::*:* * .**::. : . * . .**. .: : : : ... . : . : : : . :: * *.*::**: .: :. : * . . : :: . :. : ..: : . :. . ***. : * .: ::: :: .:*: : ..*: :. . . :.:.* .::* . .. .. .: .: . : :. : .:::: * . ..::: *:*.:* *.* :*. :. :. :.. . . :.... . : .:* . *: . . :. .. *.. . : . . :: .. :* .: ::* : : :::****: * .********:****:***** :* *: :*:* :::: . . ...**: : :. .. .::****.*********.:* :*** .: . .*:.:****:***:* :.*:: : ** * *. : :. .. * *::* ****:.** *. *:* :* . :* . : * ::: * :*: *:. *:: * .: : :*.:*.**:*:**:*.::**.*:*: :*..** .: .*. * * *** .. :* * . :: ", "identical_positions": 489, "similar_positions": 525, "identity": "24.27%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120727-15", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NE22-1", "uniprot_id": "SETD9_HUMAN", "id": "Q8NE22-1", "name": "SET domain-containing protein 9", "aln": "---MPGRLLRGLWQRWRRYKYRFVPWIALNLSHNPRTLRYVPEESKDKVISDEDVLGTLLKVFQALFLNDFNKQSEILSMLPESVKSKYQDLLAVEHQGVKLLENRHQQQSTFKPEEILYKTLGFSVAQATSSLISAGKGVFVTKGLVPKGAVVSMYPGTVYQKYEPIFFQSIGNPFIFRCLDGVLIDGNDKGISKVVYRSCNGRDRLGPLKMSDSTWLTSEIHNPLAVGQYVNNCSNDRAANVCYQEFDVPAVFPIELKQYLPNIAYSYDKQSPLRCVVLVALRDINQGEELFSNYYTIVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PRU1-1", "uniprot_id": "A0A8M1PRU1_DANRE", "id": "A0A8M1PRU1-1", "name": "", "aln": "MNNMIKALFKAFEVRWKSYRHRFVPWIALNLQKNERTLRQVENRAQDKMTADEDVFKSLVCLFTHLLKNDVKNQRQLLGLLPRSTQSKYSNVESKTHG--------------APPSTVMFETLGFSVERKISSLERAGTGVFVMRGRVPAGSIVAMYPGTIYQPDEPIFFQSVRNPFVFRCIDGILIDGNDKSISKIVYRSCSGRDRFGPLRLSDGSWLTPHPENPLAVGQYVNNCSNEKSANVCFQELDVPDGFPLELRQYLPNVNYRADSKRPLRCVVLVALRDIDDGEELFSNYYTIVH", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * *::.: **: *::**********.:* **** * :.::**: :****: :*: :* *: **.::* ::*.:**.*.:***.:: : * *. ::::****** : *** **.**** :* ** *::*:*****:** *******: ***:***:**:*******.***:*****.****:***::**.:***.. .**************:::****:**:*** **:**:*****: * *.: *************::************ ", "identical_positions": 170, "similar_positions": 73, "identity": "56.29%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120727-16", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NRG1-1", "uniprot_id": "PRDC1_HUMAN", "id": "Q9NRG1-1", "name": "Phosphoribosyltransferase domain-containing protein 1", "aln": "MAGSSEEAPDYGRGVVIMDDWPGYDLNLFTYPQHYYGDLEYVLIPHGIIVDRIERLAKDIMKDIGYSDIMVLCVLKGGYKFCADLVEHLKNISRNSDRFVSMKVDFIRLKSYRNDQSMGEMQIIGGDDLSTLAGKNVLIVEDVVGTGRTMKALLSNIEKYKPNMIKVASLLVKRTSRSDGFRPDYAGFEIPNLFVVGYALDYNEYFRDLNHICVINEHGKEKYRV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FAU2-1", "uniprot_id": "E7FAU2_DANRE", "id": "E7FAU2-1", "name": "Hypoxanthine phosphoribosyltransferase", "aln": "MSTDMAADQRKKPGVVIKDGWTGYSLELFNYPEHYKGDLECVYIPHGVIMNRIECLARDILEDIGHHDMMVLCVLKGGYKFCSDLVESIKAQSRSTNSRLTTRVEFIRFKSYLNDQSTEDLHIIGPDDLSMLKGKNVLIVEAIVDTGKTMRALLQHVETFQPKMVKVAGLLVKRVPHGAAELPDYVGFVIPNRFVVGYALDYNEYFRDLNHICVISETGKQKYKV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . **** *.*.**.*:**.**:** **** * ****:*::*** **:**::***: *:*************:**** :* **.:: :: :*:***:*** **** :::*** **** * ******** :*.**:**:***.::*.::*:*:***.*****..:. . ***.** *** **********************.* **:**:*", "identical_positions": 139, "similar_positions": 51, "identity": "61.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120727-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZN66-1", "uniprot_id": "GBP6_HUMAN", "id": "Q6ZN66-1", "name": "Guanylate-binding protein 6", "aln": "-----------------------MESGPKMLAPVCLVENNNE-QLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHLAGQNHGFPLGSTVQSETKGIW--------MWCVPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLCSTFVYNSMSTINHQALEQLHYVTELTELIKAKSSP-RPDGVEDSTEFVSFFPDFLWTVRDFTLELKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPTNDKDLLANIEKVSEKQLDPKFQEQTNIFCSYIFTHARTKTLREGITVTGNRLGTLAVTYVEAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEIS-------------------------------------------------------------------------QFKRMIDTTKNDDTPWIARTLDNLADELTAILSAPAKLIGHGVKGVSSLFKKHKLPF------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "D3ZV82-1", "uniprot_id": "D3ZV82_RAT", "id": "D3ZV82-1", "name": "", "aln": "-----------------------MASASSMEAPICLVENENE-ELRVNPKAINILERITQPVVVVAIVGLYRTGKSYLMNRLAGQNHGFNLGTTVRSETKGIW--------MWCVPHPCKPKFTLVLLDTEGLGDVEKCDPKNDSWIFALAVLLSSTFVYNSMSTINHQALEQLHYVTELTELIRTKSTP-RSEEIDDSDEFVGFFPDFIWVVRDFVLELKLDGRVITADEYLENALKLIPGRSLKAQNSNLPRECIRHFFPRRKCFVFDRPIKEKELLVHVEEMPEDELDHNFREQSNVFCSYIFSNAKAKTLKEGIMVNGNRLATLVTTYVDAINSGAVPCLENAVTTLAQRENSAAVQKAAEHYSEQMAQRLRLPTDTLQELLDVHSACEKEAIAVFMEHSFKDENQEFQKNLVVTIVEKREDFSRQNEAASLSHCQAELDKLSESLRESISCGAFSVPGGHSLYLEARKKVEQDYEQVPRKGVKANHVLQSFLQSQIVIENSILQSDKALTVNQKAMEVERAQKEAAEKEQELLRQKQKELQQVMESQERSYKENIVQLHEKMETERKNILEKQEEMLAHKLKVQEEMLNEGFKRKYEAMDSEIS-------------------------------------------------------------------------QLQKQIQQNKEQNSSLAAQIFDGFGNVLMSVLPGTGKLFGLGLKILSRKMK------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A4UUI3-1", "uniprot_id": "GBP4_MOUSE", "id": "A4UUI3-1", "name": "Guanylate-binding protein 4", "aln": "-------------------------MTQPQMAPICLVENHNE-QLSVNQEAIEILDKISQPVVVVAIVGWSHTGKSYLMNCLAGQNHVSGTLPTSQRFPSGLHRAVSDQGHLDVVHAPPHQARALVLLDTEGLGDVEKGDPKNDLWIFALSVLLSSTFVYNSMNTINHQALEQLHYVTELTELIRAKSSP-NPHGIKNSTEFVSFFPDFVWTVRDFMLELKLNGEDITSDEYLENALKLIPGNNPRIQASNSARECIRRFFPNRKCFVFEWPTHDIELIKQLETISEDQLDPTFKESAMAFASYIFTYAKIKTLREGIKVTGNGLGTLVTTYVDAINSGAVPCLDDAVTTLAQRENSVAVQKAASHYSEQMAQRLSLPTDTIQELLDVHAACEKEAMAVFMEHSFKDENQQFLKKLVELLREKNGLFLLKNEEASDKYCQEELDRLSKDLMDNIST--FSVPGGHRLYMDMREKIEHDYWQVPRKGVKASEVFQNFLQSQAIIESSILQADTALTAGQKAIAEKHTKKEAAEKEQDLLRQKQKEHQEYMEAQEKRNKENLEQLRRKLEQEREQLIKDHNMMLEKLTKEQKTFREEGYKTQAEELRREIH-------------------------------------------------------------------------QLGHNIKEMKQNGDSLVESILRSWFS-FISPPSESEKAISSVLSLLRKKDRL-----------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GE08-1", "uniprot_id": "A0A8I6GE08_RAT", "id": "A0A8I6GE08-1", "name": "", "aln": "---------------------MDMTLQIHMPGPVCLIENVKG-QLRANQKALEILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKKTGFSLGSTVQAHTKGIW--------MWCVPHPNKANHMLVLLDTEGLGDVEKGDNQNDCWIFSLAILLSSTFVYNSMGAINQQAMDQLHYVTELTDRIRARSSPDQDDGVEDSAEFVSFFPDFVWTLRDMTLKMEVDGLQVTADEYLEISLKLKEGSSKEVEKYNLPRLCIRKFFPKKKCFVFYPPT-EWKRLSQLETLQENEIDSEFLQQVAEFCLYVFKECKAKTLPGGIIVNGPRLETLVLTYLSAISSGDLPCMENAVLTLAQIENSAAVEKAITHYDQQMSQRVQLPTETLQELLDLHRTCEREAIEIFLRVSFKDEDHSFQMKLGSRLEERWNDFCKRNMEVSSNRCWALLQDIFRPLEESVKQGTYSKPGGYYLFVQETQRLKEKYQGQPKKGLQADEVLQKYLQSKEAITTAILQTDQSLTEKEKEIEVERKKAESAQAAAKLLEETQKKNEKLMEQKERSYQEHMKQLTEKMENDRIQLKAEQERILSLKLQEQKQLLQEGFREESRKLQEEMKNVEKRYKETMDHMKAESSKTKEEMQRKYEQMLEKDRNHQEHTLHMIEKMERDRAQLVAEQEKTMTLILQERELQLRNELAEERRKHEKEIQDIVAENRQIILKLESERAESAENTIKMLTELNELNLKTLGQKQKTLEDHLIQLTEQRDKDTASLMAEQGKIFDSKLQEQEENFNKKIRAQSQQHREEIWKIKKEGFSCSLM", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M9P9Q7-1", "uniprot_id": "A0A8M9P9Q7_DANRE", "id": "A0A8M9P9Q7-1", "name": "", "aln": "-----------------------------MDSPVCLIDTASDGKLCVQPAALQILQQIQQPVVVVAVVGLYRTGKSYLLNRLAGKHSGFALGSTVESKTKGIW--------MWCVPHPTKAETTLLLLDTEGLGDVDKGDSRHDSNIFSLAVLLSSTLVFNSRGTIDNKAIEELQYVTELTECIKVKSPN---EDVDNSTEFVKFFPSFIWAVRDFSLELKIDGEDATEDQYLEFALKLKHGTSKKVMEFNLPRECIKNFFPSRTCFTFPFPT-TLEKMSTLERLGPADLCPEFQEVSKRFCTCVYEKSEVKRLKDGHTVTGRVLGHLAELYVNTISSGAVPCLENAVVALAQIENQAALQEALQVYQVGMEEKKRAFPLELEQVSAEHQRLSQSATQTFMAESFRDTDGKHLKALEEEINKLFDACLRENDQASVKKCENLLLSLSATMTEKHKQGFYAKPGGYDVFCRDLEDIVKKYNSLVKKEVKAEVVLQEFLKLKSVDSKAILQADRKLSEKEKKIKEETERAVLLEQEVKAKEETQRQLKERMEVEQRSNAERMQQMKLKMEQELEQQRVEAQRALDSKLKEQAALMEKGFQDKADLMKQEME-------------------------------------------------------------------------EFKQQASDAENSRSRELKELMENTNRRHEEQMKMMMEQHRQQMREIQRSSGGGSGLLCSVM--------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0G2JTZ9-1", "uniprot_id": "A0A0G2JTZ9_RAT", "id": "A0A0G2JTZ9-1", "name": "", "aln": "MSSSNDPTVIPMAERRYGDLPETNTSDPETLTEEAVLSFHNISYRETVQSGFPLRQQTHVMERLSSISGIMGPGLNAIMGPQDGSRSLLLDVLAARRDPCGLSG------DILVNGKPQPANFKCTSGYVPQNDVIMHTVTVRDNLEFSAALRLPMTITRNEKRRRINEVLELLHLEKEQNTKPRSKELR---KRTSIAVELVTEHP--ILFLDDPTTGLDLR----TTTDIIAVLRRMSKKGRTVIFSINQPQYSIFRFFDSLTLVASGKLMFHGPAQDALEYFTSAGYQYESHNNPADFFLDVINGGLCDTEEDGHEADEHEDLYERLHQVTEKLANMYAQSPLHSDTRAKLDQLLGEQKQDRRSAMETTFVTPFWHQFGWITLRSFKNFKGFPWVTVIQAIIAVILAVFVGTIFRLLQNVCTEVKARAGLLFFLTGFECILSVSAGELFLLDRNHFLHEHTSGYYRVSSYFFGKLLAELIPRRLLPSMIFTLITYFIAGMKTGVKG--FFVTIFTVMMLASSASSLSLSLGAGENTAALPTTLITIYFMFMLFFSGLSLFSINFLPQLSWIQYLSIPHYGFRALLHNEFLGQNFCPEHNTEEVSRCQN----------------------------------------------------------------------YVIRLQDTFWKTSRNQRLVIVLGCVCVCVCVCVCVCVCVSVCLCLSLCVSVYVSLCVKCPIREYVLQ---------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .::. . . .: : . : :: * .* . ::. *.. : . . *: : * . . : : .* *: :: * *:. *. ::.:: *: .* . : :. . . : *:* .* : : * :.: * : : :: * .: .* .** . .. :* . : * : . * . : :. . : *: :: . :. . . . .: : . : : . : : . : : . . : : .. :: .: :: : . . : . : : :: : : :.: : . : . . . : ", "identical_positions": 25, "similar_positions": 133, "identity": "3.08%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120727-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88907-1", "uniprot_id": "PIAS1_MOUSE", "id": "O88907-1", "name": "E3 SUMO-protein ligase PIAS1", "aln": "MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSIPNVHSSPMPPTLSPSTIPQLTYDGHPAS-SPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRTYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGSWAPMRSKKEVQEVTASYNGVDG-CLSSTLEHQVASHNQSSNKN-KKVEVIDLTIDSSSDEEE-EEPPAKRTCPSLSPTSPLSNKGILSLPHQASPVSRTPSLPAVDTSYIN--TSLIQDYRHPFHMTPMPYDLQGLDFFPFLSGDN-QHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTSLPATNGSSSGSNSSLVSSNSLRESHGHGVASRSSAD---TASIFGIIPDIISLD", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O75925-1", "uniprot_id": "PIAS1_HUMAN", "id": "O75925-1", "name": "E3 SUMO-protein ligase PIAS1", "aln": "MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPAS-SPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGTWAPMRSKKEVQEVSASYNGVDG-CLSSTLEHQVASHHQSSNKN-KKVEVIDLTIDSSSDEEE-EEPSAKRTCPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYIN--TSLIQDYRHPFHMTPMPYDLQGLDFFPFLSGDN-QHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTSLPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTD---TASIFGIIPDIISLD", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7P1-1", "uniprot_id": "A0ACD6B7P1_DANRE", "id": "A0ACD6B7P1-1", "name": "", "aln": "MAESAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPTKLVSPAELALPGVH----PAASLPPGLTQLGFDGHGAPPSPLLPISLLGPKHELGLPHLPTNLHPVHPDVKLQRLPFYDLLDELIKPTSLASDNSQRFQETCFAFALTPQQVQQVSSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNGKPCNLPGYLPPTKNGVEPKRPSRPINITSLIRLSTTVPNTIVVSWTSEIGRSYSLAVYLVKQLSSTMLLQRLRGKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLMIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILNSCLDCDEIQFKEDGSWAPMRSKKEVQEVSASYNGIDGGCRTSVLEQNSQTNGSSGGGNRKKVEVIDLTLDSSSEEEEDEEPLPKKSCPSLSSLSPQMDNGVLNLHRQASPVSRTPSMPQVDTSYIPPPPPLIQDYRH-YYSTPT--ELSDLNFFPFLQGENHQHYN--MVMAAAASASEDHDLLLS-RFLPYGSSQLFLDPPSTPVNSSLPPINVNGGSTGNSLVSSSSLRESLGHPPGPRPTSDSTPTSAIYGSIPDVISLD", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**:*************************************************************** *:::**:*::*.** *.: *. :.** :*** *. *****:********* ****.: *******:***:************************:***************:******************************************* ***.**************************:***************:****.**:***********:******.******************************************* *****************************************************: * ***********:*************:*****:** * :*.**:: :: .*.. * *********:****:*** *** .*::*****. ** ::*:*.* :**********:* ****** ..******* :: ** :*..*:*****.*:* **** :: ****:.*:*:*** * **:** ***:*** *: .:***. * ....:..*****.***** .* *.::* *::*:* ***:****", "identical_positions": 508, "similar_positions": 92, "identity": "76.85%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120727-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q2WGJ6-1", "uniprot_id": "KLH38_HUMAN", "id": "Q2WGJ6-1", "name": "Kelch-like protein 38", "aln": "----MDEESLDG-----LLFKDHDFSSDLLRQLNSLRQSRILTDVSICAGAREIPCHRNVLASSSPYFRAMFCSSFREKSEAKVQLKGIDPPTLDQIVSYVYTGEAHIATDNVLPVMEAASMLQFPKLFEACSSYLQSQLAPSNCLGMIRLSEILSCETLKKKAREVALTSFPEVAASADLKELCALELRDYLGDDGLCGEEEKVFEALMVWIKHDLQARKRYMQELFKQVRLQYIHPAFFHHFIANDALLQSSPACQIILETAKRQMFSLCGTTVPDCKLLLHVPPRNSYQDFLILLGGRKDSQQTTRDVLLYSKQTGQWQSLAKLPTRLYKASAITLHRSIYVLGGMAVSSG-RSLVSHNVYIFSLKLNQWRLGEPMLVARYSHRSTAHKNFIFSIGGIGEGQELMGSMERYDSICNVWESMASMPVGVLHPAVAVKDQRLYLFGGEDIMQNPVRLIQVYHISRNSWFKMETRMIKNVCAPAVVLGERIVIVGGYTRRILAYDPQSNKFVKCADMKDRRMHHGATVMGNKLYVTGGRRLTTDCNIEDSASFDCYDPETDTWTSQGQLPHKLFDHACLTLQCIPRTSGLP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BSF5-1", "uniprot_id": "KLH38_MOUSE", "id": "Q8BSF5-1", "name": "Kelch-like protein 38", "aln": "----MDEELPDG-----VVFKDHSFSSDLLRQLNGLRQSKILTDVSICSGAWEVPCHRSVLASSSPYFKAMFCSHFRESREAKVQMKGISSTTLEQVITYVYTGEVHISAANVLPLMEAAAMLQYPRVFEACSSYLQSQLAPSNCLGLVRLAEILSCDSLKKKAKEVALTYFPEVAASADLKELCAMELRDYLGDDRLCGEEEKVFEALMAWVKHDLQARWRHMQELLQQVRLQYIHPAFFHHFIANDALLQSSPACQAILEMARKQIFSLYGPSAQDCKLLWRMPPRSSYQDFLLLLGGRKDNQQTTRDVLLYSGQTGQWQSLAKLPIRLYKASAVTLHRSVYVLGGMTVSEG-KSLISCGVYIFSLKLNQWRVGEPMLAARYSHRSTTHRNFIFSIGGTGEGQELLASMERYDSIRDVWESMAGMPVAVLHPAVAVKDQRLYLFGGEDIMQNPVRLIQVYHISRNTWYKMETRMIKNVCAPAVVLGEQIVIVGGYTRRILAYDPQSNKFVKCADMKDRRMHHGATVMGNKLYVTGGRRLTTDCNIEDSASFDCYDPETDTWTSQGQLPHKLFDHACLTLQCIPHMTSLS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "X1WG55-1", "uniprot_id": "X1WG55_DANRE", "id": "X1WG55-1", "name": "", "aln": "MCFKSAETSLDGPVSEILHFKDKDLISNLLLELNTLRKDRILTDVVLCSENKEIPCHRNVLVSSSPYFHAMFCSNFLETQKSRINLEGVPHEILAMIVEYVYTGSISISMELVLPLIQTASMLQYGRLFEACSTFLQAQLSADNCLSMIRLSEILHCSSLHEKARELAIKSFSDVVVSEDFCELSLPELVSYLEDDKLCVEEEQVFETLLAWIHHDPFSRHGTIHDLFRRVRLRHVHPYYLFQFIANDPLVQSSSLCTDIIESVRRLLFSVGTHCPGDLEPLWRTPRRQNCKEGLVVVGGRKNGEQTSREALLYDEQSHCWKWLAKIPLRLYRPAYVCMHSILYVLGGLTMKSGSQCTPSNTVYTLSLKTNQWRMGESMLTSRYGHQSATYLHFIFVLGGLGADGQLSNEVERYDTMFNQWEAMAPMPTAVLHPAVAAHNQRIYVFGGEDAMQKPVRMIQVYHIGRNMWCRIENRTVKNVCAPAAVIDDKIYIVGGYTRRMVAYDVKSNTFEKCENMKARKMHHSATVVNGKIYVTGGRFFNSHERVEDSDSFDCFDPKTDAWTSMGKLPFKLFDHGSVPLVYLSDKFLPT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * ** : ***:.: *:** :** **:.:***** :*: *:****.**.******:***** * *. :::::::*: * :: *****. *: ***::::*:***: ::*****::**:**:..***.::**:*** *.:*::**:*:*:. *.:*..* *: **. ** .** ** ** ***:***:*:.*::** :* :::*:::***:::** ::.:*****.*:***. * *:* .:: :**: * : * : * *.. :: *:::****:.:**:*:.***. *: *: ***:* ***:.: : :* :*****:::..* :. * ** :*** ****:**.**.:**.*:*::: :*** :** * . :* .:****:: : **:** **..*******.::**:*:***** **:***:******.** * ::*.* :*******.*:.::* ********::*** :**.* ** :** *:***.***:..*:****** :.:. .:*** ****:**:**:*** *:**.*****..:.* :. .", "identical_positions": 283, "similar_positions": 190, "identity": "47.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120730-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N0Z2-1", "uniprot_id": "ABRA_HUMAN", "id": "Q8N0Z2-1", "name": "Actin-binding Rho-activating protein", "aln": "MAPGEKESGEGPAKSALRKIRTATLVISLARGWQQWANENSIRQAQEPTGWLPGGTQDSPQAPKPITPPTSHQKAQSAPKSPPRLPEGHGDGQSSEKAPEVSHIKKKEVSKTVVSKTYERGGDVSHLSHRYERDAGVLEPGQPENDIDRILHSHGSPTRRRKCANLVSELTKGWRVMEQEEPTWRSDSVDTEDSGYGGEAEERPEQDGVQVAVVRIKRPLPSQVNRFTEKLNCKAQQKYSPVGNLKGRWQQWADEHIQSQKLNPFSEEFDYELAMSTRLHKGDEGYGRPKEGT----KTAERAKRAEEHIYREMMDMCFIICTMARHRRDGKIQVTFGDLFDRYVRISDKVVGILMRARKHGLVDFEGEMLWQGRDDHVVITLLK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BUZ1-1", "uniprot_id": "ABRA_MOUSE", "id": "Q8BUZ1-1", "name": "Actin-binding Rho-activating protein", "aln": "MAPGEREREAGPAKSALRKVRTATLVINLARGWQQWANENSTKQAQEPAGWLPGATHDLPNAPKEAGP------YQHAPKTLSPKPDRDGEGQHSEEATEVSHIKRKEVTRTVVSKAYERGGDVNYLSHRYENDGGVSEAIQPENDIDRILLSHDSPTRRRKCTNLVSELTKGWKVMEQEEPTWKSDSVDTEDSGYGGDMEERPEQDAAPVAPARIKRPLLSQANRYSETLNCKAHRKYSQVDNLKGRWQQWADEHVQSQKLNPFSDEFDYDLAMSTRLHKGDEGYGRPKEGS----KTAERAKRAEEHIYREIMELCFVIRTMARHRRDGKIQVTFGELFDRYVRISDKVVGILMRARKHGLVHFEGEMLWQGRDDHVVITLLE--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8N7UW36-1", "uniprot_id": "A0A8N7UW36_DANRE", "id": "A0A8N7UW36-1", "name": "Actin-binding Rho-activating protein", "aln": "MSTAGVQQNR-PFSRAVRKIKVASTVNSLAKSWQSWANKHSDKQDTIPSGWMPDTIIEDAKE------------KQKEKNEMKLLVTPRVVSVVGEEATDD-QIKTGIVTKAITPKCNEFGKDLVSVIKEKINTN------QLTTEDTKNFLGNESPTRRRYCGGKAGTFVKAIGRKEGKSMGSRSSSLDADDSGLG---EEASLSDNSDLNENEPKK----HVNRH--------KIKVTTMGDLRSRWQRFAEDHMEGQKLNPFSEEFDYDHAMATRLHKGDAGYGRPKEGS----KTAQRADRAQKHIYREMEEMCFIIRDMGQQDKQGQIWVTFGRLFDRYVKISDKVVGILLRCRKHKMVDFEGEMLWKGQDDDVIITLLV--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "O46052-1", "uniprot_id": "O46052_DROME", "id": "O46052-1", "name": "Costars domain-containing protein", "aln": "MTDVSHELGALRFVVDSPLSSKVAMFNNQATQHKQSQLLNPFSQDGRAASPKPTFSKDQYG--------------KPLAGSLTEMRGQKANIHVMKEMLELCQIINS-EGYDVKDEPTMRVIPFGELFNIYNYISDKVVGILLRARKHKLVDFEGEMLYQRRDDDVPVFLLKPIKEIRSEMEA-KIEDIKRAASPAPPQSTSVLMDRSAHEQKLKSRTPSPAVGKSAKSKSASPAPKAPVPVPAPAAEVTPVAGPTTSAEPAPVAESTMAAVPAPSTEPTPATAPASSTVEIEPAKPEVTEQAPVAVIVTEAPSTEETTPTTSEPQAEEAPAAVAPAGPADDLPTIVIEATAEFVRTVSVEQLAPSPGTASESSPDQSQSQPESTPA", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VZW6-1", "uniprot_id": "Q9VZW6_DROME", "id": "Q9VZW6-1", "name": "Costars domain-containing protein", "aln": "MAESQESP------QDSSVSSRITLFNQQAEQHKNWMMINPFAHYNVNEMPKRTFPEEEYG--------------RAPTGSLSEQRSLQANVRALEEILQLCDLIQK-SGRDDPID-GRKVLAFGQLFETYNNISDKLLATLLGARKYGFVDFSGETLFQGRDDTEPVRLLRPFEELQAEIIS-KVADLRCDFTEKPEEPTLLRED-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: . : . . * :. :. : : : :: : .: . . : . . . : : : . : : .: : . ", "identical_positions": 2, "similar_positions": 33, "identity": "0.52%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120807-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9D709-1", "uniprot_id": "TMM79_MOUSE", "id": "Q9D709-1", "name": "Transmembrane protein 79", "aln": "MTEPETLALLDMKEPETPEKSPPQALVL---QSEEEGGTESPGTESLRVGSSVGSPIVREGPEDGPDSTISEAATLPWGTDPHPSAPLP---------DPPGWRDIEPEPLE--------SEAPTKSEEPFKEDANLLPEKTVRAFVPIDLQCIERKPQEERILHRDAGPGELRNFLPARLSHPEPPERKWAEAVVRPPGRSCGGCGSCGGREALRAVASVVAALIFFPCLLYGAYAFLPFDAPRLPTMSSRLVYTLRCGVFATFPIVLGLLVYGLSLLCFSALRPFGEPRR---EVEIHRQYVAQSVQLFILYFFNLAVLSTYLPQDTLKLLPLLTGLFAISRLIYWLTFAVGRSFRGFGYGLTFLPLLAMLVWNLYYMFVVEPERMLTASESRLDYPDHARSVSDYRPRSWG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q3T1H8-1", "uniprot_id": "TMM79_RAT", "id": "Q3T1H8-1", "name": "Transmembrane protein 79", "aln": "MTEPETLALLDMKDTEISEKSPPQASVL---QPEEEGGTESPGAESLRVGSSVGSPTVREGPEDGPDSTISEAATLPWGTDPHPSAPLP---------DPPGWRDIGPELLE--------SEAPIKSEEPLKEDANLLPEKTVRAFVPIDLQCIERKPQEERIKHREAGPGELRNFLPARLSHPEPPERKWAEAVVRPPGRSCGGCGSCGGREALRAVASVVAALIFFPCLLYGAYAFLPFDAPRLPTMSSRLVYTLRCGVFATFPIVLGLLVYGLSLLCFSALRPFGEPRR---EVEIHRQYVAQSVQLFILYFFNLAVLSTYLPQDTLKLLPLLTGLFAISRLIYWLTFAVGRSFRGFGYGLTFLPLLAMLVWNLYYMFVVEPERMLSASESRLDYPDHVRSVSDYRPRSWG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9BSE2-1", "uniprot_id": "TMM79_HUMAN", "id": "Q9BSE2-1", "name": "Transmembrane protein 79", "aln": "MTEQETLALLEVKRSDSPEKSSPQALVPNGRQPEGEGGAESPGAESLRVGSSAGSPTAIEGAEDGLDSTVSEAATLPWGTGPQPSAPFP---------DPPGWRDIEPEPPE--------SEPLTKLEELPEDDANLLPEKAARAFVPIDLQCIERQPQEDLIVRCEAGEGECRTFMPPRVTHPDPTERKWAEAVVRPPGCSCGGCGSCGDREWLRAVASVGAALILFPCLLYGAYAFLPFDVPRLPTMSSRLIYTLRCGVFATFPIVLGILVYGLSLLCFSALRPFGEPRR---EVEIHRRYVAQSVQLFILYFFNLAVLSTYLPQDTLKLLPLLTGLFAVSRLIYWLTFAVGRSFRGFGYGLTFLPLLSMLMWNLYYMFVVEPERMLTATESRLDYPDHARSASDYRPRPWG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQN8-1", "uniprot_id": "A0A8M3AQN8_DANRE", "id": "A0A8M3AQN8-1", "name": "", "aln": "MDKGPPGPVAVPQTPQWVAEVDKLTKDVNSTEDEEEPMKSAKMEPSTLPWPENKPETQIPPVRDGETTSVRSDCTSLRGGLSRTESEREEFMMKEKRKTGEDWREMEAGKEERVSDIGLRNGVKSTLTEIELEEVNTMPENAARVFSPSITILRSTSQQEAAEHWRDQEEEARSPFLGSHGTHGTPLEEYYQDWPDTHRSHCCN-CGCCN-RDALKLGASMFTSALIFPLLVWGGYVFLPFDAPLLDSAPLRLVYTLRCSVFAVIPIVLGMLVLGVSRLWYRSLKPRFEGEKEVKQVAVHQRYVEDSISLFLLYFLQLTVMAAYLNQDLLKLIPLLTIVFAFGRLLYWVAAACGSSLRGVGFGFSFLPMLVMLVANIYFIFLSESAGSIFAP----NIPDPP--VPSNKQRFWG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* : . .: : .: : : : * * .: * .. . .** ::: . .* * .:..: .**:: . * . . * ::.* :**::.*.* * . . ** : *: .: :* * *. : : . .*. **.*. *: *: **: :: ::** *::*.*.*****.* * : . **:*****.***.:*****:** *:* * : :*:* * .: :* :*::** :*:.**:***::*:*:::** ** ***:**** :**..**:**:: * * *:**.*:*::***:* **: *:*::*: *. : *. : ** ... : * **", "identical_positions": 119, "similar_positions": 120, "identity": "28.74%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120807-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZXI3-1", "uniprot_id": "D3ZXI3_RAT", "id": "D3ZXI3-1", "name": "", "aln": "MGGEVRVLLLLG--LLHWVGGSEGRKTWRRRGQQPPQPPPPPPPPQRAEVAPGAGQPVESFPLDFTAVEGN---MDSFMAQVKSLAQSLYPCS-AQQLNEDLRLHLLLNTSVTCNDGSPAGYYLKESKGSRRWLLFLEGGWYCFNRENCDSRYSTMRRLMSSKDWPHTRTGTGILSSQPEENPHWWNANMVFIPYCSSDVWSGASPKSEK----NEYAFMGSLIIQEVVRELLVKGLSGAK--VLLLAGSSAGGTGVLLNVDRVAELLEELGYPSIQVRGLADSGWFLDNKQYRRSDCIDTINCAPTEAIRRGIRYWSGMVPERCQRQFKEGEEWNCFFGYKIYPTLRCPVFVVQWLFDEAQLTVDNVHLTGQPVQEGQWLYIQNLGRELRGTLKDVQASFAPACLSHEIIIRSYWTDVQVKGTSLPRALHCWDRS----FHDSHKASKTP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MKGCPFHLVDSCPWPHCNPSCPTIRDQFTGQEMNVAQFLMHMGFDVQTVAQQQ--------GMEPSKLLGILSSGN-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R116-1", "uniprot_id": "NOTUM_MOUSE", "id": "Q8R116-1", "name": "Palmitoleoyl-protein carboxylesterase NOTUM", "aln": "MGGEVRVLLLLG--LLHWVGGSEGRKTWRRRGQQPPQPPPPPPLPQRAEVEPGAGQPVESFPLDFTAVEGN---MDSFMAQVKSLAQSLYPCS-AQQLNEDLRLHLLLNTSVTCNDGSPAGYYLKESKGSRRWLLFLEGGWYCFNRENCDSRYSTMRRLMSSKDWPHTRTGTGILSSQPEENPHWWNANMVFIPYCSSDVWSGASPKSDK----NEYAFMGSLIIQEVVRELLGKGLSGAK--VLLLAGSSAGGTGVLLNVDRVAELLEELGYPSIQVRGLADSGWFLDNKQYRRSDCIDTINCAPTDAIRRGIRYWSGMVPERCQRQFKEGEEWNCFFGYKVYPTLRCPVFVVQWLFDEAQLTVDNVHLTGQPVQEGQWLYIQNLGRELRGTLKDVQASFAPACLSHEIIIRSYWTDVQVKGTSLPRALHCWDRS----FHDSHKASKTP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------MKGCPFHLVDSCPWPHCNPSCPTIRDQFTGQEMNVAQFLMHMGFDVQTVAQQQ--------GMEPSKLLGMLSNGN-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6P988-1", "uniprot_id": "NOTUM_HUMAN", "id": "Q6P988-1", "name": "Palmitoleoyl-protein carboxylesterase NOTUM", "aln": "MGRGVRVLLLLS--LLHCAGGSEGRKTWRRRGQQPPPPP-------RTEAAPAAGQPVESFPLDFTAVEGN---MDSFMAQVKSLAQSLYPCS-AQQLNEDLRLHLLLNTSVTCNDGSPAGYYLKESRGSRRWLLFLEGGWYCFNRENCDSRYDTMRRLMSSRDWPRTRTGTGILSSQPEENPYWWNANMVFIPYCSSDVWSGASSKSEK----NEYAFMGALIIQEVVRELLGRGLSGAK--VLLLAGSSAGGTGVLLNVDRVAEQLEKLGYPAIQVRGLADSGWFLDNKQYRHTDCVDTITCAPTEAIRRGIRYWNGVVPERCRRQFQEGEEWNCFFGYKVYPTLRCPVFVVQWLFDEAQLTVDNVHLTGQPVQEGLRLYIQNLGRELRHTLKDVPASFAPACLSHEIIIRSHWTDVQVKGTSLPRALHCWDRS----LHDSHKASKTP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------LKGCPVHLVDSCPWPHCNPSCPTVRDQFTGQEMNVAQFLMHMGFDMQTVAQPQ--------GLEPSELLGMLSNGS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "C5H5C4-1", "uniprot_id": "NOT1A_DANRE", "id": "C5H5C4-1", "name": "Palmitoleoyl-protein carboxylesterase notum1a", "aln": "MKRSLWVMQVLHWAVMLALVQCGALGARRFRGGRNPQPRRALP----SAHYRDRGETTESFSLDFTAVEEN---MDNFMTQVKNLAQSLYPCS-AQKLDYDMKLHFLENTSVTCNDGTPAGYYLKESKGSKRWLIFLEGGWYCFNKENCDSRYETMRRLMSSSKWPQTKTGTGMLSSLPEENPHWWNANMVFIPYCSSDVWSGASPKTDQ----NDYAFMGSLIIKEVVKDLLSKGLDNAK--ILLLAGSSAGGTGVLLNVDSVSELLEELGHTNIQVRGLSDSGWFLDNKQYRCTDCVDTINCAPTEVIKRGIKYWGGVVPERCRQAY-EGKEWNCFFGYKVYPTIKRPVFIVQWLFDEAQLTVDNIHLTGQPVQEGQWRYIQNLGTELRNTLKDVPAMFAPACLSHEFITRNYWTDVQVKGTSLPRALHCWDRS----LQDTSRNNKSP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------PKGCPVHLIDSCPWPHCNPTCPTIRDQSTGQEMNVIQFLMHMGFDVQKMAHQQ--------GMDPSKLLGMLSSGS-", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VUX3-1", "uniprot_id": "NOTUM_DROME", "id": "Q9VUX3-1", "name": "Palmitoleoyl-protein carboxylesterase NOTUM", "aln": "----MAVEQIDK------MAAKAGEATNKWIKPQQPLLTLLLL----LATFSQLPAVCSSSILDAASLQEKDPLRDTSMNMIQRNYMVMHSASGSGDHSRSLKRANLANTSITCNDGSHAGFYLRKHPSSKKWIVLLEGGWHCFDVRSCRSRWMRLRHLMTSSQWPETRDVGGILSPHPEENPYWHNANHVLIPYCSSDSWSGTRTEPDTSDRENSWRFMGALILRQVIAELIPVGLGRVPGGELMLVGSSAGGMGVMLNLDRIRDFLVNEKKLQITVRGVSDSGWFLDREPYT------PAAVASNEAVRQGWKLWQGLLPEECTKSY-PTEPWRCYYGYRLYPTLKTPLFVFQWLFDEAQMRVDNV---GAPVTPQQWNYIHEMGGALRSSLDNVSAVFAPSCIGHGVLFKRDWVNIKIDDISLPSALRCWEHSTRSRRHDKLKRSTEPSTAVSHPEHANNQRHQRHRQRLQRQKHNNVAQSGGQQRKHNHLSKEEREERKRLRQEQRQRRKQRRRQQQQKKANGGQEHRNKKDNSPKSSNGNDQRKQRRRQQLTAEERQEQRKRRRKAQQQQMKMQREQPAAGVFLEASAPQKTRSSNNASAGTKSKKRHRVPRVPEKCGLRLLERCSWPQCNHSCPTLTNPMTGEEMRFLELLTAFGLDIEAVAAALGVDMHTLNNMERTELVNMLTQQAN", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * : . : : : * .* ** :::: : *. * :: ::..* : . . .:: * ***:*****: **:**:: .*::*:::*****:**: ..* **: :*:**:* .**.*: *:**. *****:* *** *:******* ***: .:.: *.: ***:**:::*: :*: **. . *:*.****** **:**:* : : * : * ***::*******.: * . *..:.:::* : * *::**.* : : : *.*::**::***:: *:*:.********: ***: * ** **:::* ** :*.:* * ***:*:.* .: : *.::::.. *** **:**::* :*. : .. * : * .:*:: *.**:** :***: : **:**.. ::* :*:*:: :* .:: ::*:.:*:. ", "identical_positions": 173, "similar_positions": 162, "identity": "24.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120809-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P30926-1", "uniprot_id": "ACHB4_HUMAN", "id": "P30926-1", "name": "Neuronal acetylcholine receptor subunit beta-4", "aln": "----MRRAPS------LVLFFLVALCGRGNCRVANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYEGVNILRIPAKRIWLPDIVLYNNADGTYEVSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKYFPFDQQNCTLKFRSWTYDHTEIDMVLMTPTASMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLIIPCVLTTLLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDVPLIGKYLMFTMVLVTFSIVTSVCVLNVHHRSPSTHTMAPWVKRCFLHKLPTFLFMKRPGPDSSPARAFPPSKSC-------VTKPEATATS----TSPSNFYGNSMYFVNPASAASKSPAGSTPVAIPRDFW-LRSSGRFRQDVQEALEGVSFIAQHMKNDDEDQSVVEDWKYVAMVVDRLFLWVFMFVCVLGTVGLFLPPLFQTHAASE---GPYAAQRD--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R493-1", "uniprot_id": "ACHB4_MOUSE", "id": "Q8R493-1", "name": "Neuronal acetylcholine receptor subunit beta-4", "aln": "----MRGTP-------LLLVSLFALLQPGDCRLANAEEKLMDDLLNKTRYNNLIRPATSSSQLISIRLELSLSQLISVNEREQIMTTSIWLKQEWTDYRLAWNSSCYEGVNILRIPAKRVWLPDIVLYNNADGTYEVSVYTNVIVRSNGSIQWLPPAIYKSACKIEVKHFPFDQQNCTLKFRSWTYDHTEIDMVLKSPTAIMDDFTPSGEWDIVALPGRRTVNPQDPSYVDVTYDFIIKRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTFFLLLISKIVPPTSLDIPLIGKYLLFTMVLVTFSIVTTVCVLNVHHRSPSTHTMASWVKECFLHKLPTFLFMKRPGLEVSPARVPHSSQLH-------LTTAEATSTSALGPSSPSNLYGNSMYFVNPVPATPKSAVSSHTAGLPRDAR-LRSSGRFRQDLQEALEGVSFIAQHLESDDRDQSVIEDWKFVAMVVDRLFLWVFVIVCILGTMGLFLPPLFQIHAPSK---GL--------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4ISQ3-1", "uniprot_id": "A0A0R4ISQ3_DANRE", "id": "A0A0R4ISQ3-1", "name": "", "aln": "MGLKRCRIPAGSSMTRALCVLLCALSLARSGVCADSEERLMNWLLGKHRYNKLIRPALNRTERVTVLLQVSLAQLISVNEREQIMTTNVWLTQNWNDYRLSWDPAEYEGIDKLRIPSRHIWLPDIVLYNNADGTYEVTVFTNAIVLFNGSIAWLPPAIYKSACKIEVKHFPFDQQNCTLKFRSWTYDHTEIDLLLKSDAASMDDFTPSGEWDILALPGRRTVSPLDATYVDLTYDFIIKRKPLFYTINLIIPCVLITSLAILVFYLPSDCGEKMTLCISVLLALTVFLLLISKIVPPTSLDVPLIGKYLMFTMVLVTFSIITSVCVLNVHHRSPSTHSMPAWVKIVFLVRLPALLFMQRPRGHSARQRLRQNRRLLGLADTPGRSVMCSSASALLAASSASALSSPGLLYNKGHFGSRRAEGLNNGHGSAQDLKGNRLYCEWGSEIQEAVDGVRYVADHMMGNDDDQSVIEDWKYVAMVVDRLFLWIFVIVCVVGTLGLFLQPLFQNQTLAIQQPNTEPARRDGM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . * ** . *::**:**: **.* ***:***** . :: ::: *::**:**************.:**.*:*.****:*:.: ***:: ****::::*****************:*:** ** ***: ****************:***********************::* : :* ************:********.* *.:***:*********************** * ***************************.***************:*******:**********:*:**************:*..*** ** :**::***:** . : * : : ::::: :*.* : . .: : : .: :: . . .:* * .: .::***::** ::*:*: .:* ****:****:***********:*::**::**:**** **** :: : . ", "identical_positions": 300, "similar_positions": 108, "identity": "57.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120809-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4V889-1", "uniprot_id": "Q4V889_RAT", "id": "Q4V889-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MENSDSNDKGS-DQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGESTEEELLRRLQQIKEGPPPQSS---DENRAG------ESSDDVSNSDSIIDWLNSVRQSGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQTSENE-------------NEPSTRRLSVESMES----SSQRQMESHASESTSARPSRAERNSTEAL-EVPLT-----------RGQRRARSRSPEHRRTRARAERSRSPLHPT-IEIPRRAHHNISPQTLEQPLENEPEGSSRTRHHVTLRQQISGPELLGRGLFAASGSRNPSQGTSSSDTGSNSESSGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDS-DSEPSASVSSRNTERAESRNGRGSSGAGNSS--ASSSS--------------PSPSSNGESSESSSDLFEGTSEGGPSGPS---RRDGRHRAPVAFDESGSLPFLSLAQFFLLNEDDEDQPRGLTKEQIDNLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLSSGNRESVV", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9WTV7-1", "uniprot_id": "RNF12_MOUSE", "id": "Q9WTV7-1", "name": "E3 ubiquitin-protein ligase RLIM", "aln": "MENSDSNDKGS-DQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGESTEEELLRRLQQIKEGPPPQSP---DENRAG------ESSDDVTNSDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQTSENE-------------SEPSTRRLSVENMES----SSQRQMENSASESASARPSRAERNSAEAVTEVPTT-----------RAQRRARSRSPEHRRTRARAERSRSPLQPT-SEIPRRAP------TLEQSSENEPEGSSRTRHHVTLRQQISGPELLGRGLFAASGSRNPSQGTSSSDTGSNSESSGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQAPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDS-DSEPSASVSSRNVERVESRNGRGSSGGGNSSGSSSSSS--------------PSPSSSGESSESSSEMFEGSSEGGSSGPS---RRDGRHRAPVTFDESGSLPFLSLAQFFLLNEDDEDQPRGLTKEQIDNLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLSSGNRESVV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NVW2-1", "uniprot_id": "RNF12_HUMAN", "id": "Q9NVW2-1", "name": "E3 ubiquitin-protein ligase RLIM", "aln": "MENSDSNDKGSGDQSAAQRRSQMDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGESTEEELLRRLQQIKEGPPPQNS---DENRGG------DSSDDVSNGDSIIDWLNSVRQTGNTTRSGQRGNQSWRAVSRTNPNSGDFRFSLEINVNRNNGSQNSENE-------------NEPSARRSSGENVEN----NSQRQVENPRSESTSARPSRSERNSTEALTEVPPT-----------RGQRRARSRSPDHRRTRARAERSRSPLHPM-SEIPRRSHHSISSQTFEHPLVNETEGSSRTRHHVTLRQQISGPELLSRGLFAASGTRNASQGAGSSDTAASGESTGSGQRPPTIVLDLQVRRVRPGEYRQRDSIASRTRSRSQTPNNTVTYESERGGFRRTFSRSERAGVRTYVSTIRIPIRRILNTGLSETTSVAIQTMLRQIMTGFGELSYFMYSDS-DSEPTGSVSNRNMERAESRSGRGGSGGGSSSGSSSSSSSSSSSSSSSSSSSSPSSSSGGESSETSSDLFEGSNEGSSSSGSSGARREGRHRAPVTFDESGSLPFLSLAQFFLLNEDDDDQPRGLTKEQIDNLAMRSFGENDALKTCSVCITEYTEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLASGNRESVV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FH41-1", "uniprot_id": "E7FH41_DANRE", "id": "E7FH41-1", "name": "RING-type E3 ubiquitin transferase", "aln": "MEGQDNADQGSSDQSEIQRRRQLDRLDREEAFYQFVNNLSEEDYRLMRDNNLLGTPGEITADELLNRLRQVKDGPESPSSNITEERREAPGATEVEGTEENPSGETLLDWLNTVRQTGNTTRSGYRGNQSWRAVSQTNPNSGDFRFSLEINVNRNIAEQQTQTERLEGSQERPDGSVSEPESLMETAEVVEEPVVDELAVIVEPELPVPSTLTLNRDDNVPVDAPNPLTSTPPNLPSVEQPRRGQIRARSRSPEQRRTRARTARGRSPINLERLDGLPPTQHGIPTHNPEILPEPQVEGSSRTRQLFLSRQSTVETETHTLG--SATDVPEAPQ----EREATTGEAGASGRRPPTIMLDLQVRRVRPGEYRQRDSIANRTRSRSQTSNNTLLYETERGGFRRTFSRSERAGVRTYVSTIRIPIRRISDAGLGEATSLALQSMIRQIMTGFGELSYFMEAEVPDSNREDNPPADLSDALGNPDASTGTGASEADPYLPGHG---------------GLNQGGLEARTEEREVEGGLPG-AAGPR---ENRGRQRAPINLDETGSLPFLRLAHFFLLNEEDDDQPRGLTKEQIDNLSMRNFGESDAFKTCSVCITEYAEGNKLRKLPCSHEYHVHCIDRWLSENSTCPICRRAVLISTNRESVV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**..*. *:** *** *** *:*********************************** * :***.**:*:*:** . .. :*.* . :.::: ...::::****:***:******* **********:******************* ..* ::.* .**.: : * :*. . :* . .:: .* :. ..:* :. * *.* *******::******: *.***:: : : . * : *******: . **. .* * :*:. :..* . .:..*: .**:*****:********************.*******:.***: **:******************************* ::**.*:**:*:*:*:************** :: **: . . : . .. .:*...:. .. . . ...* .:.:.. .** * .:. .. **:***: :**:****** **:******:*:**************:**.***.**:**********:************************************* * ******", "identical_positions": 343, "similar_positions": 146, "identity": "51.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120810-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6A378-1", "uniprot_id": "A0A8I6A378_RAT", "id": "A0A8I6A378-1", "name": "", "aln": "VKKIRPHRPSPATEKGAASPGEGDRDPPPPAHEDIAVKGSAAAAG-TGPGTGAAAAAAAAAVPPPHPAAAAAAAAAAAAAAAVAAAPPHPNIRALQTPAPQQIPRGPVQQPLEDRIFPPTVSAVYSTVTQVARQPGPPTPSPYSAHEINKGHP-----NLAATPPGHASSPGLSQT--------------------PYPSGQNAGPATLVYPQAPQTMNSQPQAR----------SPFFQRPQIQPPRAAIPNSSPSLRPGAQTPTA----VYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFAN--AYGTPFYPSQPVY-QSAPIIVPTQQQPPPAKREKK---TIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQQLPSQAPEHSPVVYGTVESAHLAAS----TPVTAASDQKQEEKPKPDPVFQSPSTVLRLVLSGEKKEQAGQIPETAAGEPSPEPPRTSSPTTLPPLARSSLPSPMSAALSSQQLLT--AEDKCELSSSKD-DAPPVRSPTSCTAAPGPSLTD--DIGLCKKPCGVAPPDGQLVSSPVLINEMNGVGEKLPAKENTVDMV---------------RQEVLPLTLELEILE---HPQEERKVECTPTPITPSTMPSFSPAPPTPPASP--PCTPVVL--SATIARSPAVATVIQRVVDEGESLRTCLSKDAKETQDKAEAESDGQTEETADPQNAHAGRSPAPVQTATTAPKTWK--------------KTKERTRTPDEVLEAEAEPKAEEELSVDSVLEPEQEKMS-QGFQFERDPSTLKRAKAEEENGE-EAEPVRNGAESASEGEGGDANSGSTDSSGD---------------GVTFPFKAESWKPADTEGKKQYDREFLLDIQFMPACIQKPEGLPPISDVVLDKINQPRLPMRTLDPRILPRGP--DFTPAFADFGRQTPGGRGVPLLSVGPRRSQPGQRREPRKIIT-VSVKEDVHLRKAENAWKP--SQKRDSHADDPESIKTQELFRKVRSILNKLTPQMFNQLMKQVSALT-----VDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMAD-----KPGNTVNFRKLLLNRCQKEFEKDKADDDVFEKKQK----ELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHD----EESLECLCRLLTTIGKDLDFEKAKPR---------MDQYFNQMEKIVKER-----KTSSRIRFMLQDVIDLRLCN-WVSRRADQGPKTIEQIHKEAKIEEQEEQRKV-QQLMTKEKRRPG----VQR----VDEGGWNTVQGAKNSRVLDPSKFLKITKPTIDEKIQLVP-----KAQLGSWGKGSSGGAKASETD------------------------------------ALRSSASSLNRFSPLQPPAP-SGSPSATPLDFDSRRALTSRGSMGREKSDKPLPAGTARPNTFLRG-SSKDLLDNQSQEEQRREMLETVKQLTGGVDAERASTEADRSKARELVKSEVCTVP-APDKPALSEEEVERKSKSIIDEFLHINDFKEATQCIEELSAQGPLHVFVKVGVEFTLERS-----------------------QITRDHMGHLLYQLVQSEKLSKQDFFKGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELIVEFSKPLLPVGRAGVLLSEILHLLCRQMSHKKVSALWREADLSWKDFLPEGEDVHNFLLEQKLDFTESEG-PCSSEALSKKELSAEELSQRLEKLIMEDKADDERIFDWVEANLDESQMSSPTFLRALMTAVCKAAIVADCSTFRVDTAVIKQR-VPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80XI3-1", "uniprot_id": "IF4G3_MOUSE", "id": "Q80XI3-1", "name": "Eukaryotic translation initiation factor 4 gamma 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSQPQAR----------SPFFQRPQIQPPRAAIPNSSPSIRPGVQTPTA----VYQANQHIMMVNHLPMPYPVTQGHQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFAN--AYGTPFYPSQPVY-QSAPIIVPTQQQPPPAKREKK---TIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPASTPTPPQQLPSQVPEHSPVVYGTVESAHLAAS----TPVTAASDQKQEEKPKPDPVFQSPSTVLRLVLSGEKKEQAGQMPETAAGEPTPEPPRTSSPTSLPPLARSSLPSPMSAALSSQPLFT--AEDKCELPSSKEEDAPPVPSPTSCTAASGPSLTD--NSDICKKPCSVAPHDSQLISSTILINEMNGVGEKLSAKENTVGML---------------RQEVLPLTLELEILE---HPQEELKVECTPTPIAPSMLPAFSPAPPTPPTSP--PCPPVVL--SAAIARSPAVATEVQRVADEGESLRTCLSKDAKEMQDKAESESDGQAEETADPQSLHSGRSPAPVQTATTAPKSWK--------------KTKEQTRTPDEVLEAEAEPKAEEELAVDSVLEPEQEKMS-QGFPSERDPSALKRGKAEEGNGE-EAEPVRNGAESASEGEGGDGNSGSADSSAD---------------GLTFPFKAESWKPADTEGKKQYDREFLLDIQFMPACIQKPEGLPPISDVVLDKINQPRLSMRTLDPRILPRGP--DFTPAFADFPRQTPGGRGVPLLNVGPRRSQPGQRREPRKIIT-VSVKEDVHLRKAENAWKP--SQKRDSHADDPESIKTQELFRKVRSILNKLTPQMFNQLMKQVSALT-----VDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMAD-----KPGNTVNFRKLLLNRCQKEFEKDKADDDVFEKKQK----ELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHD----EESLECLCRLLTTIGKDLDFEKAKPR---------MDQYFNQMEKIVKER-----KTSSRIRFMLQDVIDLRLCN-WVSRRADQGPKTIEQIHKEAKIEEQEEQRKV-QQLMTKEKRRPG----VQR----VDEGGWNTVQGAKNSRVLDPSKFLKITKPTIDEKIQLVP-----KAQLGSWGKGSSGGAKASESD------------------------------------ALRSSASSLNRFSPLQPPAP-SGSPSATPLEFDSRRALTSRGSMGREKSDKPIPAGTARPNTFLRG-SSKDLLDNQSQEEQRREMLETVKQLTGGLDAERASTEADRSKTRELAKSEMCAVP-APDKPALSEEEVERKSKSIIDEFLHINDFKEATQCIEELSAQGPLHVFVKVGVEFTLERS-----------------------QITRDHMGHLLYQLVQSEKLSKQDFFKGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELIVEFSKPLLPVGRAGVLLSEILHLLCRQMSHKKVGALWREADLSWKDFLPEGEDVHHFLLEQKLDFTESEG-PCSSEALSKKELSAEELSQRLEKLIMEEKADDERIFDWVEANLDESQMSSPTFLRALMTAVCKAAIIADCSTFRVDTAVIKQR-VPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQAGKGVALKSVTAFFTWLREAEEESEDN", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43432-1", "uniprot_id": "IF4G3_HUMAN", "id": "O43432-1", "name": "Eukaryotic translation initiation factor 4 gamma 3", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNSQPQTR----------SPFFQRPQIQPPRATIPNSSPSIRPGAQTPTA----VYQANQHIMMVNHLPMPYPVPQGPQYCIPQYRHSGPPYVGPPQQYPVQPPGPGPFYPGPGPGDFPN--AYGTPFYPSQPVY-QSAPIIVPTQQQPPPAKREKK---TIRIRDPNQGGKDITEEIMSGGGSRNPTPPIGRPTSTPTPPQQLPSQVPEHSPVVYGTVESAHLAAS----TPVTAASDQKQEEKPKPDPVLKSPSPVLRLVLSGEKKEQEGQTSETTAIVSIAELPLPPSPTTVSSVARSTIAAPTSSALSSQPIFTTAIDDRCELSSPRE-DTIPIPSLTSCTETSDPLPTNENDDDICKKPCSVAPNDIPLVSSTNLINEINGVSEKLSATESIVEIV---------------KQEVLPLTLELEILE---NPPEEMKLECIPAPITPSTVPSFPPTPPTPPASP--PHTPVIVPAAATTVSSPSAAITVQRVLEEDESIRTCLSEDAKEIQNKIEVEADGQTEEILDSQNLNSRRSPVPAQIAITVPKTWK--------------KPKDRTRTTEEMLEAELELKAEEELSIDKVLESEQDKMS-QGFHPERDPSDLKKVKAVEENGE-EAEPVRNGAESVSEGEGIDANSGSTDSSGD---------------GVTFPFKPESWKPTDTEGKKQYDREFLLDFQFMPACIQKPEGLPPISDVVLDKINQPKLPMRTLDPRILPRGP--DFTPAFADFGRQTPGGRGVPLLNVGSRRSQPGQRREPRKIIT-VSVKEDVHLKKAENAWKP--SQKRDSQADDPENIKTQELFRKVRSILNKLTPQMFNQLMKQVSGLT-----VDTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLVTLKVPMAD-----KPGNTVNFRKLLLNRCQKEFEKDKADDDVFEKKQK----ELEAASAPEERTRLHDELEEAKDKARRRSIGNIKFIGELFKLKMLTEAIMHDCVVKLLKNHD----EESLECLCRLLTTIGKDLDFEKAKPR---------MDQYFNQMEKIVKER-----KTSSRIRFMLQDVIDLRLCN-WVSRRADQGPKTIEQIHKEAKIEEQEEQRKV-QQLMTKEKRRPG----VQR----VDEGGWNTVQGAKNSRVLDPSKFLKITKPTIDEKIQLVP-----KAQLGSWGKGSSGGAKASETD------------------------------------ALRSSASSLNRFSALQPPAP-SGSTPSTPVEFDSRRTLTSRGSMGREKNDKPLPSATARPNTFMRGGSSKDLLDNQSQEEQRREMLETVKQLTGGVDVERNSTEAERNKTRESAKPEISAMS-AHDKAALSEEELERKSKSIIDEFLHINDFKEAMQCVEELNAQGLLHVFVRVGVESTLERS-----------------------QITRDHMGQLLYQLVQSEKLSKQDFFKGFSETLELADDMAIDIPHIWLYLAELVTPMLKEGGISMRELTIEFSKPLLPVGRAGVLLSEILHLLCKQMSHKKVGALWREADLSWKDFLPEGEDVHNFLLEQKLDFIESDS-PCSSEALSKKELSAEELYKRLEKLIIEDKANDEQIFDWVEANLDEIQMSSPTFLRALMTAVCKAAIIADSSTFRVDTAVIKQR-VPILLKYLDSDTEKELQALYALQASIVKLDQPANLLRMFFDCLYDEEVISEDAFYKWESSKDPAEQNGKGVALKSVTAFFTWLREAEEESEDN", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BDQ6-1", "uniprot_id": "A0A8M3BDQ6_DANRE", "id": "A0A8M3BDQ6-1", "name": "", "aln": "-----------------------MSLPPKVVPKPAAVAVSGHVTG-PAPPTQLRAALTSVSLPPGAQNAPPSAVP------------------------PTQIPRAALS--LDERMFPAHSG--VTAVYSVSRHPGPPFPG----HDLSKTHP-----NLAGTPPGHATSPALSQVSVPAGPSYRILKPWETGGAPPYNPAQNAGSAPLVYSPQTQPMNVQPQTRPFVTGPRPTHHQFIHRSQMQPARPTLPTNNPSIRPGSQTPTAT---VYPPNQPIMMT-MTPMPFAT-QTHQYYIPQYRHSAP-YVGPPQQYAVQPPGSGTFYPGPSPAEYPTPYAAGPPYYTGQTVYPPSPPIIVPAPMPPPPTKREKKPSSQIRIRDPNQGGKDITEEIMFG--SRNPTPPAGHPASTLTPPAGRPSSTPTPPSGRLSSTPTPPQRPSNCQTPEQTAYVNQTQRLSESPAPMDGKPS----LAIDDRPKMESGPIKSISPGPRPSESCLEKREISSLPLLVSSSPE---VDVSSHPTSG------CIKPTAAG--EPEFISPSATKAQTYQVISG----------EESVPEASPRLSASLSLRVVNGVNEPQ-TPSSYEEPE---------------VQEALKMSSSCEIQG---TSFMEESGQEVPVALEELQAEHLPSLAAHVPLIPGVQASSITSSTTSVLAPPPGLAPLVQSVVLEVS------------EQNKTSDDVQLKAQDASESQTQSNSRKFTPAQAVPVVPKPWK--------------KPND-----EDLMMETLKKENEEETSKDCSAGDEMVLQSSLGTYSSPFTVPEHQEKHSEENGETETEPFRNGVETESTDSG-----VTLGDSRG---------------SMCSPTQLIQEGLVQSNGKRQYDRDFLLGFQFMPACVQKPEGLPPISDVVLDKMNQNKLPLRSVDPRLISRGTPQDFTPAFADFSRQMAGGRGAPLLNVR--------RLPPRKIIVNLSVSDDVQLKKAENAWKP--GMKREGVAEDPETIRTQELFRKVRSILNKLTPQMFHQLMKQVTDLT-----INTEERLKGVIDLVFEKAIDEPSFSVAYANMCRCLATLKVPTAD-----KPNTTVNFRKLLLNRCQKEFERDKVDDVVLERKQK----EIDSATSPTEKERLQEELEEAKDKARRRSTGNIKFIGELFKLKMLTEPIMHDCVVKLLKNHD----DESLECLCRLLTTIGKDLDFEKAKPR---------MDQYFNQMEKIVKER-----KTSSRIRFMLQDVIDLRLHN-WVSRRADQGPKTIEQIHKEAKLEEQEEQRKVHQQLLSKDMKRRP----DQREQRSMREETWNTVPTTKNSRTIDPTKIPKISKPQIDEKIQLGP-----RAQIN-WVKGSSGGAKASDSE------------------------------------LTRSAGNTLNRYSALQSSTSQSSSTPAQTSESEPRRSLGSRGSMGRERSEKPVSLGPSRPGPFGRGSSAKELIDNMVPEETRREGQDSHHTSR-KASISEEKCEMENSRSAESVKSETLLVSGVSEKPVLSEEEIERKSKAIIDEFLHINDYKEAVQCVLEIEQPSMLCVFVRMGLESTLERS-----------------------QKAREHMGLLYYQLIQKGILPHSQLYKGFSEMLEQADDMAIDIPFIWLYLAELLSPLLKEGGINMRELFSELSKPLLPVGRAAILFSEILHLLCKQMSHRKVGDLWRESGLNWADFLPEGEHLPAFISQHKLEFTVSDI-SPVSPASAKPSLSPEELFKQLEQLLLEDMSSDEQIFDWIEANLDESQMSSSPFLRALMTAICKAAVKDESTSCRVDTAIIQKR-LPILHKYFDSDTERQLQALYALQSLIVALDQPPNLLRMFFDCLYDEDVISEDAFYQWETSKDPAEQLGKGVALKSVNAFFTWLREAEEESEDN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A8DZ29-1", "uniprot_id": "A8DZ29_DROME", "id": "A8DZ29-1", "name": "", "aln": "---------------------MQQAIPTLPTQSDIDKAMQPHSAQNMILPANKKTKKYDQQVPTSKPQSLHQPLQP-------------------QHSHPTAQPQFQINKAYNVVSILKASAQIAQQSPHLTNQQHPPIHHPQQTQQHQQSYTNVVNRSLSASEPVRAQSSVICNGSSILTVNSRQLNSGDMNSTAIYNISSYRKLTGSLDGNVCFLNVQDIKQNGNISGSVVSNKSIVGVGSEKSSCTGVSINNQIVLPNAQIGTSMGIAGTTTAGTSYMHEKNIVGVSVNCVNTSKKYDFNNSSLLSNNSYPASTAEYVSTGNNNSGNTRSNPQSGGIFRGPPSTPNAPRGASGGATRHVHVQPMYSQPLHQNMVLQQYTQYNPRQQTFPASHLQYAPAPMPYYQYQYVPTLQQQPPHTRSAVTVNTNVNVGNNLQPVQSGPN---GPLPVPGASSSQIQLLTSTVQPGASTVMGVGGPGSTMGQVGVPPMVGVGVMTTSVQPQPVQVQPASRRRHQHRLQIIDPTTKKNILDDFDKTKSNTDNEFSDQVTSTNTPATVLSEGPIRIPQQESVGLNNLTSTSSQGSESRTNAPYIPIETTPISRTDVGPTPIVSAMTDAPSVEILPTPQRGRSKKIPIVSPKNVSESIVAPITDETDDAGSTPISRATEESMPPNQTHPNLLISDSSKHKQAVSNSEISKDAPTGLKEMHVAELESSVASENHPAGILDVNVNKSSQSLDFSADPEIDSIGAISPTSPNAVSPILHEVLDNTELSKKLENSTTERFKDSQSVEKPTHQELSLRNATDETEISAMALQDVNSLDNNQIEKTYPSKPKLNVDVSEDISSRESAIKSTSTKNTGVDVGLQSDSKPETTLNDKQDSTDLKVKVSAKISSIINYNEGQWSPNNPSGKKQYDREQLLQLREVKASRIQPEVKN-VSILPQPNLMPSFIRNNNNNKRVQSMVG------IIGNRSNESAGNYIGKQMSMSGVQSGGGRSSMKGMIHVNLSLNQDVKLSENENAWRPRVLNKSDGDSDAKSALEKDELVRRVRGILNKLTPERFDTLVEEIIKLK-----IDTPDKVDEVIVLVFEKAIDEPNFSVSYARLCQRLAAEVKVIDERMESETKSNSAHFRNALLDKTEQEFTQNVSQSTAKEKKLQPIVDKIKKCTDANEKAELEAFLEEEERKIRRRSGGTVRFIGELFKISMLTGKIIYSCIDTLLNPHS----EDMLECLCKLLTTVGAKFEKTPVNSKDPSR--CYSLEKSITRMQAIASKTDKDGARVSSRVRFMLQDVIDLRKNK-WQTSRNE-APKTMGQIEKEAKNEQLSAQYFGTLSSTTPGGSQGGSGKRDDRGNSRYGESRSSSAYGGSHSQRGDNGNLRHQQQNNVGGNVSGGAGHSNGNNDENTWHVQTSKGSRSLAVDSNKLEGLSKLSDQNLETKKMGGLTQFIWISSDTTRLSSAPTPTPSNPFAVLSSLIDKNSNERDRDRSGPRNKGSYNKGSMERDRYDRGMHSRTGSSQGSRENSSSRGGQQGRTLLSSSVQKSTSHSKYTQQAPPTRHTVKAQSSVGSSNVNTGPLYRGSEQQTSATFSQTTRSVAPVAVFIEASETDLKLIKSVVSEIVDLSAASKEVTPGAVSCIKRVPEKLRCSFIYYILTDYLHLANVGKQYRRYLSIAVSQLIQQNYISADHLRLAYNEFTVYANDLIVDIPELWLYILQFAGPLIVKKILTISDLWNNNLKENSPSNVAKKFLKTYLIYCTQEVGPNFARNMWIKFNLKWSDFMPESE-VADFIKFNRLEYVENESKSPVIDHRETPEKHVKNVIDHIEHLLKEGTTAD-CIIDYSNG---NIMVVDKLFIRGLTETLSNFSIHYKDNSYKLESETFQKFCIPVLQRYIDSNEDHQLECLYTLQLLVHGLEHPRGLLSELIGELYDAFVIQKESLCKWRDSKD--QSAGKGVAVKSLNPFFNSLLNDDAN----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P39935-1", "uniprot_id": "IF4F1_YEAST", "id": "P39935-1", "name": "Eukaryotic initiation factor 4F subunit p150", "aln": "----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTDETAHPTQSASKQESAALKQTGDDQQE------SQQQRGYTNYNNGSNYTQKKPYNSNRPHQQRGGKFGPNRYN-NRGNYNGGGSFRGGHMGANSSN--VPWTGYYNNYPVYYQPQQMAAAGSAPANPIPVEEK----------------------------SPVPTKIEITTKSGEHLDLKEQHKAKLQSQERSTVSPQPESK------LKETSDSTSTSTPTPTPSTNDSKASSEENISEAEKTRRNFIEQVKLRKAALEKKRKE-----------------------------------QLEGSSGNNNIPMKTTPENVEEKGSDKPE---------VTEKTKPAEEKSAEPEVKQETPAEEGEQGEKGQIKEES---------------TPKVLTFAERLKLKKQQKEREEKTEGKENKEVPVQEETKSAIESAPVPPSEQVKEETEVAETEQSNIDESATTPAIPTKSDEAEA------------EVEAEAGDAGTKIGLEAEIETTTDETDDGTNTVSHILNVLKD-------------------------------ATPIEDVFSFNYPEGIEGPDIKYKKEHVKYTYGPTFLLQFKDKLNVKADAEWVQSTASK----------------------------------IVIPPGMGRGNRSRDSGRFGNNSSRGHDFRNTSVRNMDDRANSRTSSKRRSKRMNDDRRSNRSYTSRRDRER--------GSYRNEEKREDDKPKEEVAP------------LVPSANRWVPKFKSKKTEKKLAP---------DGKTELLDKDEVERKMKSLLNKLTLEMFDAISSEILAIANISVWETNGETLKAVIEQIFLKACDEPHWSSMYAQLCGKVVKELNPDITDETNEGKTGPKLVLHYLVARCHAEFDKGWTDKLPTNEDGT------------PLEPEMMSEEYYAAASAKRRGLGLVRFIGFLYRLNLLTGKMMFECFRRLMKDLTDSPSEETLESVVELLNTVGEQFETDSFRTGQATLEGSQLLDSLFGILDNIIQTA-----KISSRIKFKLIDIKELRHDKNWNSDKKDNGPKTIQQIHEEEERQRQLK--------------------------------NNSRSNSRRTNNSSNRHSFRRDAPPASKDSFITTR----------TYSQRNSQRAPPPKEE------------------------------------PAAPTSTATNMFSALMGESDDEE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.. . .. : : . . .... . : . * * .: . . . . .: * .: . . . ... . . .. . . . : . . . : : : :: . . . : . : . . : :. . . : . : . . : . .. . .*: : . :: . . . * : . .. .: .: : ..: : *: * . : .:*: *:::.:***** : *. : .:: : . : :. ** :* ** *** :* **.:* :. . . : *: : . ** :. :. :.. . .: . :**. * ::*** *:::.:** ::..*. *:: :: **.: .**.*:* .:: .. ::. : :: * . : ***::* * *: :** : * : : : .***: **.:* : :. . .. : .: : .. : .* : . : .: .. * :: * . ", "identical_positions": 66, "similar_positions": 212, "identity": "3.31%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120810-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q91XA8-1", "uniprot_id": "KLD8A_MOUSE", "id": "Q91XA8-1", "name": "Kelch domain-containing protein 8A", "aln": "MEVPNVKDFQWKRLAPLPSRRVYCSLLETGGQVYAIGGCDDNGVPMDCFEVYSPEADQWTSLPSLPTARAGVAITALGKRIMVIGGVGTNQLPVKVVEMYNIDEGKWKKRSVLREAAMGISVTAKDYRVYAAGGMGLDLRPHNYLQHYDMLKDMWVSLAPMPTPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIESRSWTKFPNIPCKRAFS-SFVTLDNHLYSLGGLRQGRLYRQPKFLRTMDVFDMEQGGWLKMERSFFLKKRRADFVAGGLSGRVIVAGGLGNQPTVLETAEAFHPEKNKWEALPPMPTPRCACSSIVFKNCLLAVGGVSQGLSDAVEALFVSDS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IYD2-1", "uniprot_id": "KLD8A_HUMAN", "id": "Q8IYD2-1", "name": "Kelch domain-containing protein 8A", "aln": "MEVPNVKDFQWKRLAPLPSRRVYCSLLETGGQVYAIGGCDDNGVPMDCFEVYSPEADQWTALPRLPTARAGVAVTALGKRIMVIGGVGTNQLPLKVVEMYNIDEGKWKKRSMLREAAMGISVTAKDYRVYAAGGMGLDLRPHNHLQHYDMLKDMWVSLAPMPTPRYAATSFLRGSKIYVLGGRQSKYAVNAFEVFDIETRSWTKFPNIPYKRAFS-SFVTLDNHLYSLGGLRQGRLYRQPKFLRTMDVFDMEQGGWLKMERSFFLKKRRADFVAGSLSGRVIVAGGLGNQPTVLETAEAFHPGKNKWEILPAMPTPRCACSSIVVKNCLLAVGGVNQGLSDAVEALCVSDS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B5V3-1", "uniprot_id": "A0ACD6B5V3_DANRE", "id": "A0ACD6B5V3-1", "name": "", "aln": "MMVPSAHEFHWQSLASLSSARVYHSLADVGGQLYLVGGCDASGQPTSALELYSPEVDRWLSLPPMPTPRAGAAVAVLGKQLLVVGGMGKEQRPLKAVEVYNTDEGKWRKRCSLREASMGVSVTVKDGRALAVGGMGPDLLPRSVLQQYDLRKDVWALLPAMPTPRYDTSICLLGSKIYVAGGRQCKRLVKAFEVFDMENRTWSSLPSLPCKRSYSGVLWDSAGCLCWLGGLRQGGIHQSSKFTKNVNIFDTNKGVWLKSEDTVPLKTKRADFAAAIVRGRMIVAGGLGHQPSVLDTVEAFHPEKRKWERLSPMATPRCSASSIVIRDRLLVVGGVNQVPSSAHEILYVKEEEIL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **..::*:*: **.*.* *** ** :.***:* :**** .* * ..:*:****.*:* :** :**.***.*::.***:::*:**:*.:* *:*.**:** *****:**. ****:**:***.** *. *.**** ** *:. **:**: **:*. *..****** :: * ****** ****.* *:******:*.*:*:.:*.:* **::* : . * ******* :::..** :.:::** ::* *** * :. **.:****.*. : **:*******:**:**:*.***** *.*** *..*.****:.****.:: **.****.* *.* * * *.:. ", "identical_positions": 190, "similar_positions": 106, "identity": "53.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120813-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6DN90-1", "uniprot_id": "IQEC1_HUMAN", "id": "Q6DN90-1", "name": "IQ motif and SEC7 domain-containing protein 1", "aln": "--------------------------------------------------------------------------------------------------MWCLHCNSERTQSLLELELDS------------------------GVEGEAPSSETGTSLDSPSAYPQGPLVPGSSLSPDHYEHTSVGAYGLYSGPPGQQQRTRRPKLQHSTSILRKQAEEEAIKRSRSLSESYELSSDLQDKQVEMLERKYGGRLVTRHAARTIQTAFRQYQMNKNFERLRSSMSENRMSRRIVLSNMRMQFSFEGPEKVHSSYFEGKQVSVTNDGSQLGALVSPECGDLSEPTTLKSPAPSSDFADAITELEDAFSRQVKSLAESIDDALNCRSLHTEEAPALDAARARDTEPQT-----ALHGMDHRKLDEMTASYSDVTLYIDEEELSPPLPLSQAGDRPSSTESDLRLRAGGAAPDYWALAHKEDKADTDTSCRSTPSLERQEQRLRVEHLPLLTIEPPSDSSVDLSDRSERGSLKRQSAYERSLGGQQGSPKHGP-HSGAPKSLPREEPELRPRPPRPLDSHLAINGSANRQSKSESDYSDGDNDSINSTSNSNDTINCSSESSSRDSLREQTLSKQTYHKEARNSWDSPAFSNDVIRKRHYRIGLNLFNKKPEKGVQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSTMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCICNPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVKPERKMKLEDFIKNLRGVDDGEDIPREMLMGIYERIRKRELKTNEDHVSQVQKVEKLIVGKKPIGSLHPGLGCVLSLPHRRLVCYCRLFEVPDPNKPQKLGLHQREIFLFNDLLVVTKIFQKKKNSVTYSFRQSFSLYGMQVLLFENQYYPNGIRLTSSVPGADIKVLINFNAPNPQDRKKFTDDLRESIAEVQEMEKHRIESELEKQKGVVRPSMSQCSSLKKESGNGTLSRACLDDSYASGEGLKRSALSSSLRDLSEAGKRGRRSSAGSLESNVE------------------------------------------------FQPFEPLQPSVLCS--------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R0S2-1", "uniprot_id": "IQEC1_MOUSE", "id": "Q8R0S2-1", "name": "IQ motif and SEC7 domain-containing protein 1", "aln": "--------------------------------------------------------------------------------------------------MWCLHCNSERTQSLLELELDS------------------------GVEGEAPSSETGTSLDSPSAYHQGPLVPGSSLSPDHYEHTSVGAYGLYAGP-GPQQRTRRPRLQHSTSVLRKQAEEEAIKRSRSLSESYELSSDLQDKQVEMLERKYGGRLVTRHAARTIQTAFRQYQMNKNFERLRSSMSENRMSRRIVLSNMRMQFSFEGPEKVHSSYFEGKQVSVTNDGSQLGALVPSECGDLSDP-ALKSPAPSSDFADAITELEDAFSRQVKSLAESIDDALNCRSLHSEEVPASDTARARDTEPKP-----GLHGMDHRKLDEMTASYSDVTLYIDEEELSPPLPLSQAGDRPSSTESDLRLRSGGAAQDYWALAHKEDKADTDTSCRSTPSLERPEPRLRVEHLPLLTIEPPSDSSVELSDRSDRSSLKRQSAYERSLGGQQGSPKHGP-HGGPPKGLPREEPELRPRPPRPLESHLAINGSANRQSKSESDYSDGDNDSINSTSNSNDTINCSSESSSRDSLREQTLSKQTYHKETRNSWDSPAFSNDVIRKRHYRIGLNLFNKKPEKGIQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSAMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCVCNPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVKPERKMKLEDFVKNLRGVDDGEDIPRETLIGIYERIRKRELKTNEDHVSQVQKVEKLIVGKKPIGSLHHGLGCVLSLPHRRLVCYCRLFEVPDPNKPQKLGLHQREIFLFNDLLVVTKIFQKKKNSVTYSFRQSFSLYGMQVLLFENQYYPNGIRLTSAVPGADIKVLINFNAPNPQDRKKFTDDLRESVAEVQEMEKHRIESELEKQKGVVRPSMSQCSSLKKESGNGTLSRACLDDSYASGEGLKRSALSSSLRDLSEAGKRGRRSSAGSLESNVE------------------------------------------------FQPFQPPQPPVLCS--------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B5E1-1", "uniprot_id": "A0ACD6B5E1_DANRE", "id": "A0ACD6B5E1-1", "name": "", "aln": "MDGHFAYIDMENPTENPNKAAEYLKELNKIIETQQELLEKQKNRIEELEQQVCDLCQENACLKDQHQRHLATCRLQQQGNSHPTLGAIKENVIQEKNESEGLRVSNVRRHASLPLDVTDNPGNFIVSHCQRSYPCRKWKSASLGVEGEAPGGESGPSLDNSGGYLRGPVSRSAIISGEHFDGPPLYAH-------EVRQRPRRPKLQHSQSILRKQAEEEAIKRSRSLSESYELSTDLQDKQVEMLERKYGGRFITRHAARTIQTAFRQYQMNKNFERLRSSMSENRMSRRIVLSNMRMQFSFEGPEKVHSSYFEGKQVSLTDDGSKLGALVQSERGEMVPA-NMKSPAVQSDFTDAITELEDVFSRQVKSLAESIDDALNCRSLHGDEGQSEATRGHPDLEQEVTYQVKPSHGSEHRKRDEMTASYSDVTLYIDEEELSPPLPLSQSVDRPSSTESDLRIRSLNSSQDYWSLAHKDEKADTDTSCRSTPSLECQEQRLRIDHLPLLTIEPPSDSSVELSDRSDRSSLKRQNAYDRGIASQQGSPKHIPSHALPPRGPAREDEAPRHRP-RQLESHLAINGTANRQSKSESDFSDGDNDSINSTSNSNDTINCSSESSSRDSLREQTLSKQTYHKETRNSWDSPAFSNDIIRKRHYRIGLNLFNKKPEKGIQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSAMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCICNPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVKPERKMKLEDFVKNLRGVDDGEDIPREMLVGIYERIRKRELKTNEDHVSQVQKVEKLIVGKKPIGSLHHGLGCVLSLPHRRLVCYCRLFEVPDPNKPQKLGLHQREIFLFNDLLVVTKIFQKKKNSVTYSFRQSFSLYGMQVLLFENQYYPNGVRLTSALPGADIKVLINFNAPNPQDRKKFTDDLRESIAEVQEMEKYRIESELEKQKGVVRPSISQSSGLKKETGNGNLSRTSLDDSYAMGEGLKRSALSSSLRDLSDAGKRGRRSSAGSLDSNMEGSIISSPHIRRRATSSRDCPSRQQSIPNSSSLLGSLFGTKRGKSPSLPSQSSHPSHPTLISHTPHPSNLHHTARDGVTVTETQAQMHPHHAQFCHMQNPPPYHHHHHYHPPAHIQHPPHQYHPPPGPSSSHSHSHSQHGHGPHPSHSSHPSHSQHAPHHHSQPPAPPPAASSTKPKHSGISTVV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: .. * :: * *:: . *******..*:*.***....* :**: .: :* :*:: ..: *: :**.***:**** *:***********************:*****************::*****************************************************************:*:***:***** .* *:: . :**** .***:********.********************** :* : : * * : ** :*** ***************************: ***********:*: .:: ***:****::*************** * ***::***************:*****:*.*****.**:*.:..******* * *. .*:. .**: * ** * *:*******:**********:*******************************************:************:********************:*********************************************************:***********************************:*********************************************:*************** *:************************************** ************************************************************************************:****::*****************************:********:****************:**.*.****:***.***:.****** *****************:*************:**:* *. .* :*.::. ", "identical_positions": 783, "similar_positions": 109, "identity": "62.09%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120813-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A0G2JUG7-1", "uniprot_id": "IQEC1_RAT", "id": "A0A0G2JUG7-1", "name": "IQ motif and SEC7 domain-containing protein 1", "aln": "--------------------------------------------------------------------------------MACRR--RYLSSLETGS------------SLSTDRYS--------------------------VEGEAPSSETGTSLDSPSAYHQGPLVPGSSLSPDHYEHTSVGAYGLYAGP-GPQQRTRRPRLQHSTS----------------------------------------------------------------------VLRKQAEEEAIKRSRSLS------------ESYELSSDLQDKQVEMLERKYGGRLVTRHAARTIQTAFRQYQMNKNFERLR-SSMSENRMSRRIVLSNMRMQFSFEGPEK-------VHSSYFEGKQVSVTNDGSQLGALVPSECGDLSDP-ALKSPAPSSDFADAITELEDAFSRQVKSLAESIDDALNCRSLHSEEVPASD-------------TARARDTEPKPGLHGMDHRKLDEMTASYSDVTLYIDEEELSPPLPLSQAGDRPSSTESDLRLRSGGAAQDYWALAHKEDKADTDTSCRSTPSLERPEPRLRVEHLPLLTIEPPSDSSVELSD-----------------RSDRSSLKRQSAYERSLGGQQGSPKHGPHGGPPKGLPREEPELRPRPPRPLES--HLAINGSANRQSKSESDYSDGDNDSINSTSNSNDTINCSSESSSRDSLREQTLSKQTYHKETRNSWDSPAFSNDVIRKRHYRIGLNLFNKKPEKGIQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSAMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCVCNPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVKPERKMKLEDFVKNLRGVDDGEDIPRETLIGIYERIRKRELKTNEDHVSQVQKVEKLIVGKKPIGSLHHGLGCVLSLPHRRLVCYCRLFEVPDPNKPQKLGLHQREIFLFNDLLVVTKIFQKKKNSVTYSFRQSFSLYGMQVLLFENQYYPNGIRLTSAVPGADIKVLINFNAPNPQDRKKFTDDLRESVAEVQEMEKHRIESELEKQKGVVRPSMSQCSS-LKKESGNGTLSRACLDDSYASGE----------GLKRSALSSSLRDLSEAG---KRGRRSSAGSLESNVEFQPFQPSQPPVLCS-----------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R0S2-1", "uniprot_id": "IQEC1_MOUSE", "id": "Q8R0S2-1", "name": "IQ motif and SEC7 domain-containing protein 1", "aln": "--------------------------------------------------------------------------------MWC----LHCNSERTQS------------LLELELDSG-------------------------VEGEAPSSETGTSLDSPSAYHQGPLVPGSSLSPDHYEHTSVGAYGLYAGP-GPQQRTRRPRLQHSTS----------------------------------------------------------------------VLRKQAEEEAIKRSRSLS------------ESYELSSDLQDKQVEMLERKYGGRLVTRHAARTIQTAFRQYQMNKNFERLR-SSMSENRMSRRIVLSNMRMQFSFEGPEK-------VHSSYFEGKQVSVTNDGSQLGALVPSECGDLSDP-ALKSPAPSSDFADAITELEDAFSRQVKSLAESIDDALNCRSLHSEEVPASD-------------TARARDTEPKPGLHGMDHRKLDEMTASYSDVTLYIDEEELSPPLPLSQAGDRPSSTESDLRLRSGGAAQDYWALAHKEDKADTDTSCRSTPSLERPEPRLRVEHLPLLTIEPPSDSSVELSD-----------------RSDRSSLKRQSAYERSLGGQQGSPKHGPHGGPPKGLPREEPELRPRPPRPLES--HLAINGSANRQSKSESDYSDGDNDSINSTSNSNDTINCSSESSSRDSLREQTLSKQTYHKETRNSWDSPAFSNDVIRKRHYRIGLNLFNKKPEKGIQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSAMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCVCNPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVKPERKMKLEDFVKNLRGVDDGEDIPRETLIGIYERIRKRELKTNEDHVSQVQKVEKLIVGKKPIGSLHHGLGCVLSLPHRRLVCYCRLFEVPDPNKPQKLGLHQREIFLFNDLLVVTKIFQKKKNSVTYSFRQSFSLYGMQVLLFENQYYPNGIRLTSAVPGADIKVLINFNAPNPQDRKKFTDDLRESVAEVQEMEKHRIESELEKQKGVVRPSMSQCSS-LKKESGNGTLSRACLDDSYASGE----------GLKRSALSSSLRDLSEAG---KRGRRSSAGSLESNVEFQPFQPPQPPVLCS-----------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6DN90-1", "uniprot_id": "IQEC1_HUMAN", "id": "Q6DN90-1", "name": "IQ motif and SEC7 domain-containing protein 1", "aln": "--------------------------------------------------------------------------------MWC----LHCNSERTQS------------LLELELDSG-------------------------VEGEAPSSETGTSLDSPSAYPQGPLVPGSSLSPDHYEHTSVGAYGLYSGPPGQQQRTRRPKLQHSTS----------------------------------------------------------------------ILRKQAEEEAIKRSRSLS------------ESYELSSDLQDKQVEMLERKYGGRLVTRHAARTIQTAFRQYQMNKNFERLR-SSMSENRMSRRIVLSNMRMQFSFEGPEK-------VHSSYFEGKQVSVTNDGSQLGALVSPECGDLSEPTTLKSPAPSSDFADAITELEDAFSRQVKSLAESIDDALNCRSLHTEEAPALD-------------AARARDTEPQTALHGMDHRKLDEMTASYSDVTLYIDEEELSPPLPLSQAGDRPSSTESDLRLRAGGAAPDYWALAHKEDKADTDTSCRSTPSLERQEQRLRVEHLPLLTIEPPSDSSVDLSD-----------------RSERGSLKRQSAYERSLGGQQGSPKHGPHSGAPKSLPREEPELRPRPPRPLDS--HLAINGSANRQSKSESDYSDGDNDSINSTSNSNDTINCSSESSSRDSLREQTLSKQTYHKEARNSWDSPAFSNDVIRKRHYRIGLNLFNKKPEKGVQYLIERGFVPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDEMDFSTMELDEALRKFQAHIRVQGEAQKVERLIEAFSQRYCICNPGVVRQFRNPDTIFILAFAIILLNTDMYSPNVKPERKMKLEDFIKNLRGVDDGEDIPREMLMGIYERIRKRELKTNEDHVSQVQKVEKLIVGKKPIGSLHPGLGCVLSLPHRRLVCYCRLFEVPDPNKPQKLGLHQREIFLFNDLLVVTKIFQKKKNSVTYSFRQSFSLYGMQVLLFENQYYPNGIRLTSSVPGADIKVLINFNAPNPQDRKKFTDDLRESIAEVQEMEKHRIESELEKQKGVVRPSMSQCSS-LKKESGNGTLSRACLDDSYASGE----------GLKRSALSSSLRDLSEAG---KRGRRSSAGSLESNVEFQPFEPLQPSVLCS-----------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A8W6-1", "uniprot_id": "A0AB13A8W6_DANRE", "id": "A0AB13A8W6-1", "name": "", "aln": "-------------------MDSRTENPTKAAGYLKELNKIIETQQTLLERQKRRIFELEQHVSDLCAENSRLRLEYQRHLLTCRLRSIRENSPEQQSEYGGSRIVRRHASLPVEMTDSPNSLRSAVC-RRTVPCRQWKSASLGVEGTVESSEPGPSVDTSIGYGRGPVTHSSSLSPDQSEG-SLYSHSIQSGP----QRPQRPKLQHSQS----------------------------------------------------------------------ILRKQAEEEAIKRSRSLS------------ESYELSTDLQDKKVEMLERKYGGRFITRHAARTIQTAFRHYQMNKNFERLR-SSMSENRMSRRILLSNMRMQFSFEAPEK-------VHSSFFEGRQMSLMEESSHIGAMVQPGE---KVPVILEAPETQNDLTDTITELEDTFSKQVKSLAESIDDALNCRSLHKEEIQPEQ-------------TVCELQQK-RELPQPDEHHRLDEI----CDVTLFIDEEELSPLV-------QPSSAESDQHTQSVSASQEYWSMD-----ANMDTSARSTPSLDYQSPKLCVD-LPVLTIEPPSDSSADASD-----------------RSEQGLVQTQNVPKQTTAAPRANPKHGLPARVP-SLSGEEEPLR---HRQVVS--HLATNGS--RQSKSESDFSDGDNDSINSNSNSIDTINSESSSS------QQNLSKQTYHKDTRNSWDSPASSSDIMRKRQYRIGLNLFNKKPEKGIQYLTERGFIPDTPVGVAHFLLQRKGLSRQMIGEFLGNRQKQFNRDVLDCVVDELDFSGMELDEALRKFQAQIRVQGEAQKVERLIEAFSQRYCICNHDVVRQFRNPDTIFILAFAIILLNTDMYSPNVKIERKMKLEDFVKNLRGVDDGEDIPREMLVGIYERIQKKELKTNEDHVSQVQKVEKLIVGKKQMGSLHHGLGCVLSQAHRRLVCYCRLFEVPDPNRLQKLGQHQREIFLFNDLLVVTKIFQKKKNSVTYSFRQSFSLYGMQVMLFENQFYPNGIRLTSAIPGADFKVLINFNAPNIQDRKRFISDLRESIAEVQEMEKYRIESELEKQKGVVRPSMSQSMSGLKKETGNGSMGRTSLDDSYAMGE----------GLKRSALSSSLRDLSEAG---LHL--------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VP80-1", "uniprot_id": "Q9VP80_DROME", "id": "Q9VP80-1", "name": "", "aln": "MSEADLKNLSQNSDGDQELLLHQTTQSLLMASSIMFVGNQGGPGGSAGGVAPPGPVSLPLPLSINMPHHHVHAMPYNVDELLRENNALHAKIKELSLERDRLLCEVSNLRLELDMSELKRLPVDLDDNFPQKSLERSGSTQYELAGAQQPGSANASTCTDSGSVGGYVYLQNHYAPGAHSSSAAINYPAQQHPQMVYQIQQYPTCHQQQQQQHLQQQQHLHQTGAGHYMQVTATGGGQYHHHHMLHGHGHHAHHHGGAVVIAGSGVGTGLGSGATSVIMQHQQQQQQQQNMHKKNSIRNGGDVLKRTRAQSAYELSQDLLEKQIELLERKYGG-VRARNAAVTIQRAFRHYMMVKKFASITAMAKAEKRLSRRMVVTASSLGLAEEGASSSSAYGSATESQLTEQQQQQQAQQQQQPRVTIMAGPAGAASPGLSRTPPTRSLSMRERRQLDCSPIPRSQSGASPASISSSTVSTSALASHPHVNLLHAAEPHYYNAQALPQGAAYYTSYHGSPHDLSYASSADTSLNASWVNTSGHSPHTPYYSAAQIYMRPKGGSTTPTPSCSGSTGSGSGGSGSGSSKKVPPEVPKRTSSITAQQQTQLLLLQRQTPPPPSLLRTNGLCKTAENGSLTSVQSSGSDSSVTSAERNLNSDLGSDRSNSPHTWKRGTALNSSQQFSTHSADSAGAVSGGGVGVAGGAGVYAAQMQAAVAAATAAGGMPPADDHAISSHTSAAQYEQHEQQQHEQQQLQAAAAAAGVAQNYKMSETIRKRQYRVGLNLFNKKPEKGITYLIRRGFLENTPQGVARFLITRKGLSRQMIGEYLGNLQNQFNMAVLSCFAMELDLSGRQVDVALRKFQAYFRMPGEAQKIERLMEIFSQRYCECNADIVGRLRSSDTIFVLAFAIIMLNTDLHTPNLKPERRMRVEDFIKNLRGIDDCHDIDKDMLMGIYDRVKSDEFKPGSDHVTQVMKVQATIVGKKPN----------LALPHRRLVCYCRLYEIPDVNKKERPGVHQREVFLFNDLLVITKIFSKKKTSVTYTFRNSFPLCGTVVTLLDMPNYPFCIQLSQKVDG---KILITFNARNEHDRCKFAEDLKESISEMDEMESLRIEAELERQKSARNRAPGNAENRDSGVADVEVCPCPYQQGSQASGEQAPNSADNSQQLKRSALSNSLLDMHEQFGNEKPQRRGSVGSLDSGMSISFQSTTTSSASRENAAAIAAAANAAAAAKMRFNMPPTAAIATPSNVYAAPGMQAYTHANFVQQSQAAYMLQQQQMLQQQAQMQAQAQAQAQAQAQAQAQAQAQAQAQPLTGRIPGRERKASRTDENGRSTEV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . * : . : * ......* : . * : . :*. . : : * * : * ::. . ::* ::: :::..*: .:**** ** :*::*:******* . :*:** *** ***:* * *:* : : :*:*:***:::: : :: *.... ..*. * :* . :: .: . : . * .:* . . :*: : : :* *.. . : . * . . : * . : ::: . ** .:.. : ..: . : .. .. ..*. * :* :.*. .* :: *: . . : : .. :... * . . . : : . . .*: :: :: : . . . ::. . * :. :* .:* : . . .: :***:**:************: ** .***: :** ***:**: ***********:*** *:*** **.*.. *:*:* ::* ******* :*: *****:***:* ****** ** .:* ::*..****:******:****:::**:* **:*::***:*****:** .** :: *:***:*::. *:*...***:** **: ***** *: .**********:*:** *: :: * ****:********:****.***.****:**:**.* * * *:: ** *:*:. : * *:**.*** * :** :* .**:**::*::***. ***:***:**.. . : .:. . . :. . :.* * ** *******.** *: * ", "identical_positions": 292, "similar_positions": 267, "identity": "21.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120813-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9HA90-1", "uniprot_id": "EFCC1_HUMAN", "id": "Q9HA90-1", "name": "EF-hand and coiled-coil domain-containing protein 1", "aln": "MEPVSTGAEAGMEGAGGDPYRRPARRTQWLLSALAHHYGLDRGVENEIVVLATGLDQYLQEVFHHLDCRGAGRLPRADFRALCAVLGLRAEGATTAGQAAGDGNSRDVTPGDAAAELATDGDSDTDEEARLALRAEPPELTFRQFHARLCGYFGTRAG-----PRLPRGALSEHIETQIRLRRPRRRRRPPCAPGPDSGPDCER------------------------------------VARLEEENSSLRELVEDLRAALQSSDARCLALQVGLWKSQASTHEMG-------------------------------------HGGPEAAV-------RELRQAQGALAAAEARAGRLRRGQAEVRRRAEEARQVVLRSLHRVRELEALAQQVPGLQRWVRRLEAELQRYRSEDSQLPTPQLANPEPGDKSNEPEDAGTRDPDPTPEGAWQSDSSSGSRALDEVDEQLFRSVEGQAASDEEEVEEERWQEEKKTPAAEAKTLLARLSSCRGRCDDQTAEKLMTYFGHFGGANHAHTLGELEACIAMLVEQLRTQGCGGRTLGTSEEEA------ELQQKVEENEHLRLELQMVETERVRLSLLEEKLVDVLQLLQRLRDLNISKRALGKILLSTLDAFRDPTHEGRPSPAAILDALHQALAACQLLRRQPSAPAS-AAAALTNPLLVSC", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B7H3-1", "uniprot_id": "A0ACD6B7H3_DANRE", "id": "A0ACD6B7H3-1", "name": "", "aln": "MEKLDA----------CDPYSRPARRTQWIVSTLAYHYGLDRGVENEIIVLATGLDQYLQEIFHHLDCQGDGKIPTEDFNILCEILGLG----------------KDCDLEECAGILDN----------------LPKEFTFRQFHAKLCGYFSTKAGCHYENGRLLVGKESEHIETQIRLRSPLRRREKLLSLGTTSKRESEKTPSPTVDRHRSGRRQLGSCTRECYEEIVALEEAEDRIAKLEEENASLRELVEDMRAALQSSDARSLALQVGLWKSHSKHKPEGGCFIAHQRRTVQKPNISGSLKDIQSFLREVELLRASRDGQVEEAMFFNQKLEQELRISRETSLMLEECNRTLKKEQVEMRKRVEEARQAVLSGLKKVKELETKASHIPVLQRHIEQLEMELLYYRSEVSKTSVAFIHKPD--RRYNGASQTVSR-CCLDTEQDRHSPTGRAETVSDTMEEQLFRSVEGQAASDEE---EERWTGEQQRQVDEVKRILTRLSCCGDRCDEKAVKKLLSHFGDSRTEESQTAVLELLEKVTRLNKQLELKESQARRAEMDTDQMRDALVQELQQKAEETELLHLELQMLETERVRLSLVEDKLMDVLQLLQQLRELNVSRRSLGKILLSTLESCSDPQH-GKAHILEVLNALCHELAACEILSNGETIERSQSHQSLTNSLLISC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** :.: *** ********::*:**:************:************:******:* *::* **. ** :*** :* :.*. * . * *:*******:*****.*:** ** * *********** * ***. : *. * :.*: :*:*****:********:**********.**********::. : * .* * *: :*** :: : * *:: *.*:*:*.*****.** .*::*:***: *.::* *** :.:** ** **** *: ... : :*: : * ..:: :* .* :* :. .. . * ::**************** **** *:: . *.* :*:***.* .***:::.:**:::**. : :: ** :: * :**. : . .* . :: *****.**.* *:*****:*********:*:**:*******:**:**:*:*:*********:: ** * *:. :*:** : ****::* . : * : :***.**:**", "identical_positions": 285, "similar_positions": 141, "identity": "41.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120813-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1LWD2-1", "uniprot_id": "F1LWD2_RAT", "id": "F1LWD2-1", "name": "", "aln": "MALQAWDWEEEERASTRPLSTASDYHSASECETEEYPKSRTPGNEWDSEDQFSS-LHSSEGPACISNSDVPQVVPCKFVISLAFPSLLGNKGKPTNVPDK-KKAAKSENRAGKARQFYHIEYFFLPDDIEPKIVDIVVFPNVAKVFLDSGIKTVKPWKDDDKFWVSWSQTFHVNMTKELLKKMNFHKITLKLWDTKDKVSKKVRYHRVKTSAYSEDSDSF--EEVKNLVLSQKRLSVIVDGKVNIVPEELKEENVPGDQEKAEKHSKSPQ-----EPETPSKN-EECEKLLKMEES-SSRRTTMKTP-ISLSGATMMEIKELIEKPSLSSLTNMVEKQKSQLKGKEIEVKKKNPKKVKKYQTEEERDQRQEG-APWKQSTFSIQLPVMPLLAGWQTVICRGSEKSANILDCFLTLKTEVPIMTEEQKQELNPLTIKIRCASCLPVQPVSIHDLERLCSPVYCRYQFHKTPVHETKGEPHGTHVFFHDLNVIFLGAMHPSDLREYLEGPPMVVEVHDRDRKSEEYSRKPTLFGEDLIDSYYNLQAFISSKDTENNPFESQNKIWDPYGVAKVSFADLLLGYKYLNLIVPIHNCEPKSPNWSQDSRSRRTIGLQAPTDV-QHSSVPIGNYLEANSLLKLRVDVAVPLSSSWSRVPEFNLMGTHFGRIIFVFSAKKLSLLQNLLHDITVINAKALELDSYPLQKIQQILSAFKVRVKIQEQQSLDVLTGFHLLDGKIHLFILEGLADHGLRRLWESYQSSVTTSNRAACKVLYDSRLLFRHRLYADLETVLFHVHLFRPVSVLLRYPALYVRGAVSRMTFQALSRIHDICHSSTKLKDVISRDLLPSSCMIKDLSQEFGVPISQEELIDGQVLPVSPQLDDNEEDVQHQTSNLPLEIQVHQDKYLQWRNNMLLKNQVHRDSVVQKNITEAYQFTKQSQKSMKRIIRIAIPENKTVHNYSTQTMNSTELAKKQMLQEMAKEPRKRFTYSQNYLSAMVDLQDPKEEEKKAQKKSRQAWLT-------------------AGGFQVWGLQSAIGSHQQDLRLPPIRELNEEWQESALFAN------VLKPVLDRERWGWSQRHKDFDLYKKPPLDFQLPSLLAPKRASGGRRKADIRSSEQRWRSQVTPRPPS----LHGSISMQPHDLFSLSDP----------------SSCTKHSVSPNLHVS---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A571BDQ7-1", "uniprot_id": "A0A571BDQ7_MOUSE", "id": "A0A571BDQ7-1", "name": "", "aln": "MSLQAWDWEGEEGSSMGPHSVAS------ESEMEENLKSRIPAHDWDSEDQFSSSLHSSEGPACISNSDVPQIVPCRFEISLAFPVLIGNKGKPPNVPDK-KKSAKTETRTGKARQFYHIEYFFLPDDIEPKIVDIVVFPNVAKVFLESGTKTVKPWRDDDKVWVSWSQTFHVNVTKELLKKLNFHKITLRLWDTKDRVSKRARYQRVKASAYSEDLESL--EEVKHLVLSHKKLSLISIGKTNPISEELKEENLPGDQEKSEKHLKSPQ-----EPEAPSKNDEECEKLLKMEESPLSRRTISKTP-ISLSGATMMEIKELIEKPSLSSLTNMLEKQKSQLKGKDTEVKKKNPKKVKRYQAEEEGDQKPETPAAWKQSIFSIQLPIMPLLAGWRTVICRGSEKSANILDCFLTLKTEVPIMTEQQKQDLNPLTIKIRCVSCLPIQPVSIHDLERLCSPVYCRYQFHKTPVHETKREPHGTHVFFRDINVVFLGAMNPSDVREYLEGPPMVVEVHDRDRKLEEYSRKPALFGEDLMDSYFNLQAFVSHRDTETNPYESQNKIWDPYGIARVSFADLLLGYKYLNLIVPIHNCEPKSPNWSQDSRNRRTMGVQVPTDVLQHSSIPKGNYLEANSLLKLRVDIAVPLSG-WSRAPQLDLMGTHFGRIIFVFHAKKLSLLQSLLQDITMINAKALELDCYPLQNIQQILSAFKVRVKIQEQQDLDVLTGFHLLDGKIHLFILEGLADRGLRQLWESYQSSVTASNRAACKVLYDSRLLFCHRLYADLETILYHVHLFRPVSVLLRYPALYVRGAVSRMAFKALSRIHDICQSSTRLKEVVMRDLLPSSSMIKELSQEFGIPISQEDLTDGKLLTALPQPDTSNEDIQRRTSTLPLEIQVHQEKYLQWRNDMLLKNQVHRDSIVQKNITEAYQFTKKSQKPIRKVIRIAIPENKTVHNYSAQTMNSTELAKKQMLKEMAKEPRKRFTYSQNYLSAMVDFQDPKEEEKKAQKKSRQAWLT-------------------AGGFQVWGLQSSTGSSQQDLKLPPIRELNEEWQENALFTN------VLKPVLDRDRWSWSQRHLDFDLYKKPPLYFKLPRLPSPKRASGRRRKANIGSSGRRWRSRVASKPLS----SPESSSTHPQDLFSLSDHHLVLKTLSRLTSASRGSSLGLYHPNPTFHSRWFH------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9ULG3-1", "uniprot_id": "CFA92_HUMAN", "id": "Q9ULG3-1", "name": "Uncharacterized protein CFAP92", "aln": "MSLHAWEWEEDPASIEPISSITSFYQSTSECDVEEHLKAKARAQESDSDRPCSS-IESSSEPASTFSSDVPHVVPCKFTISLAFPVNMGQKGKYASLIEKYKKHPKTDSSVTKMRRFYHIEYFLLPDDEEPKKVDILLFPMVAKVFLESGVKTVKPWHEGDKAWVSWEQTFNITVTKELLKKINFHKITLRLWNTKDKMSRKVRYYRLKTAGFTDDVGAFHKSEVRHLVLNQRKLSEQGIENTNIVREESNQEHPPGKQEKTEKHPKSLQGSHQAEPETSSKNSEEYEKSLKMDDSSTIQWSVSRTPTISLAGASMMEIKELIESESLSSLTNILDRQRSQIKGKDSEGRRKIQRRHKKPLAEEEADPTLTG--PRKQSAFSIQLAVMPLLAGTHCLPCS--------QQLLLVLWPERP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RRA8-1", "uniprot_id": "A0A8M1RRA8_DANRE", "id": "A0A8M1RRA8-1", "name": "", "aln": "-----------------MNSTSPDMERIEDLHLNSALHTEYEVEELNNYDPYIGMPEYSSGDDQSFTTDSSHTVSCTVSIALAIFKEHEECFTEKRKKGTKNETSNEVVEAPRAEGYYCIEYNMLPDDPEPTRVDLVMFGLAAKLYMASETKVLKPWREGNQVWVSWSQTLKLKVSKELLIKMASHKITVKVWDSKEKLSFKARNDRPKAFRLPQDRSGE-----------------------------------------------------------------------DPDQMGGIKKVVCKMR--------AMNEENLRTRKSVSGIS-----------------------PTKKTLFPEITEHTEVN---LEKEAASLELSFTPLLAGSTMLTDCLGFCSGGVKEGFWNVTLDQQLISEELKVELNPLVIRVLSACSLPSP-----PIQAKCLPVYCQYKFHNMPIHRSKGYDHSANICFRDVNVIFTGLMSHGKLVEFLRGPPIEIEVHDRDRKNEKRFTKPTVFGTDPNDARIATVDLWNTAFNLDTEHDDH-----PHGIAKLDLSDLLQGCRYLKLTLPIKCSASEHIEQKVIN---------------SDTAIPVGHYLEANAQLKVQVEIAYPFHS----EDENDCEDCPFGRIIYVFRYNNTPILFKLTSEILQINAEAFQLHHYPEETIQRVLSGHIISTKERENKRMNVLTGFHLMDKALHLFVLEGLKDQAVKRLWSAVPMKLDGDEEEQVTVLYNSDFGFSERLYDTLDVGLSPICLFKPLETIMREPLVFIRNAVPHACLEAMKRISHIRQAKT-LQEAVHSNLFPLANMVLSLNKEFGVDVGREE----LWLAAETQEPQDVSDHHNIRKRMYTPLDNFNRQYFQWKRNKCKN----GKNFIQANIEDVYRASNDLKKSKSYVVLDTITDSQTIN-YHNTETNSTIRSGEQLYRELSKNSTAIGIFCPGFRSSIESNQHPKRPDDARIEELRKPWTENVLHGNKLKPTLSRSRLPWIQRYQDFELYSKPPSQFGPELPLSIHLAGESLYEEQIQAARAQHNRWLRKILLGETSTGSGRVPEFRCHMRKANLDKLQDILKDKPMKYSLRRPGMALKPIPVISVVQLSEMTGSAEEEANIPFTPGPFQNHSLSWDKNAIPRYSSQYSKFHFRDYWRPHSFLHKRSVLPFTDEEKRIHCYQKPAEAPQTPFVTDYFKLNRNITEIRTNKDVTLHVL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * :. : . :. ::. .: :. . . *. .:* .: *.* . *:**: : . . :: .: . : . :* *** :**** **. **:::* .**::: * *.:***::.:: ****.**:::.::**** *: ****:::*::*:::* :.* * *: .:* . . :: : : *: ::* *:*.:: *: * : ::. *::*.. ***** : : : : : ", "identical_positions": 63, "similar_positions": 99, "identity": "5.04%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120813-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86XE3-1", "uniprot_id": "MICU3_HUMAN", "id": "Q86XE3-1", "name": "Calcium uptake protein 3, mitochondrial", "aln": "-MAALRRLLWPPPRVSPPLCAHQPLLGPWGRPAVTTLGLPGRPFSSREDEERAVAEAAWRRRRRWGELSVAAAAGGGLVGLVCYQLYGDPRAGSPATGRPSKSAATEPEDPPRGRGMLPIPVAAAKETVAIGRTDIEDLDLYATSRERRFRLFASIECEGQLFMTPYDFILAVTTDEPKVAKTWKSLSKQELNQMLAETPPVWKGSSKLFRNLKEKGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKR-EIKGDEEKRAMLRLQLYGYHSPTNS-VLKTDAEELVSRSYWDTLRRNTSQALFSDLAERADDITSLVTDTTLLVHFFGKKGKAELNFEDFYRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVENTSVFLENVRYSIPEEKGITFDEFRSFFQFLNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKFSPHLVNTVFKIFDVDKDDQLSYKEFIGIMKDRLHRGFRGYKTVQKYPTFKSCLKKELHSR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CTY5-1", "uniprot_id": "MICU3_MOUSE", "id": "Q9CTY5-1", "name": "Calcium uptake protein 3, mitochondrial", "aln": "-MAALRRFLWPPPRLSPALAPQQPFLSPWGRPAGTAPGMSGRPFSCREEDEGAVAEAAWRRRR-WGELSIAAAAGGGLVGLVCYQLYGDPRAD------PSELAAPELEDPPRGRGLLPIPVAAAKETVATGRAITEDLDLYATSRERRFRLFASIECEGQLFMTPYDFILAVTTDEPKFAKTWKSLSKQELSQMLSETPPVWKGSSKLFRNLKERGVISYTEYLFLLCILTKPHAGFRIAFNMFDTDGNEMVDKKEFLVLQEIFRKKNEKR-ETKGDEEKRAMLRLQLYGYHSPTNS-VLKTDAGELVSRSYWDTLRRSTSQALFSDLAERADDITSLVADTTLLVHFFGKKGKAELNFEDFYRFMDNLQTEVLEIEFLSYSNGMNTISEEDFAHILLRYTNVENTSVFLENVRYSISEEKGITFDEFRSFFQFLNNLEDFAIALNMYNFASRSIGQDEFKRAVYVATGLKLSPHLVNTVFKIFDVDKDDQLSYKEFIGIMKDRLHRGFRGYKTVQKYPTFKSCLKKELHSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B5U7-1", "uniprot_id": "A0ACD6B5U7_DANRE", "id": "A0ACD6B5U7-1", "name": "", "aln": "MMAAVRRFLGLRSKFTSSVNGLNIYFNSRN--------------SPRE-------RAALRRVG----TGLCIALGG--FAFVYYQHSSS----------PDRRRAASLR-----ALISPLPAVAAKEKASAS----GEDEVSLSAHEHRFRLFSSVEFDGQLYMTPLDFIESVTMSEPKKKRFWKSLTKQELDKILSDTPPVWKGSSRLFRNLRERGLIAYTEYLFLLCILTKPHAGFKIAFNMFDADGNQMVDKREFMVLEEIFRKKNEKRKERGGDAESSSQLNVELYGYQGSVSSNVLKKEQPQCEPRSFWDVLKLGARIVLFSDLMEHVPEN---VTDTTLLVHFFGRKGKSELNFDDFYRFMDNLQTEVLEIEFLSYSKGMTTISEEDFARILLRYTTVENITGYLENVHQSIPDEKGITFEEFRSFFQFLNNLEDFAIAMQMYNFANRPIGQDEFGRAVYVATGLKLSRHLVNTIFKIFDVDHDDQLSYKEFIGIMKDRLHRGSWGYKGEERFTSFKGCMKKELSAK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ***:**:* .:.:..: : :.. . * ** .** ** .:. * ** ..:* ** .. *.. *.. . : *:*..****..: . : :: :::*:*****:*:* :***:*** *** :** .*** : ****:****.::*::*********:*****:*:*:*:******************:*******:***:****:**:**:********** * ** *. : *.::****:....* ***.: : .**:**.*: .: .***** *:. : *:**********:***:****:**********************:**.********:******.*** : :****: **.:******:******************::*****.*.****** **********:* *****:*******:******************** *** :::.:**.*:**** ::", "identical_positions": 299, "similar_positions": 120, "identity": "56.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120813-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P70423-1", "uniprot_id": "CTR3_MOUSE", "id": "P70423-1", "name": "Cationic amino acid transporter 3", "aln": "----------------------------------------------------MLWQALRRFGQKLVRRRVLELGMGETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSIVICFLVAALSSVLAGLCYAEFGARVPGSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISRTLKGTILL-KMPHVLAEYPDFFALALVLLLTGLLVLGASKSALVTKVFTGMNLLVLSFVIISGFIKGELRNWKLTKEDYCLTMSESNGTCSLDSMGSGGFMPFGLEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISMFICFLAYFGVSSALTLMMPYYKLHPESPLPEAFSYVGWEPARYLVAIGSLCALSTSLLGSMFPMPRVMYSMAEDGLLFRVLAKVHSVTHIPIVATLVSGVIAAFMAFLFELTDLVDLMSIGTLLAHSLVSICVLILRYQPDQEMKS---------------------VEEEMELQEETL--EAEKLTVQALFCPVNSIPTLLSGRVVYVCSSLLAVLLTVLCLVLTWWTTPLRSGDPVWVTVVVLILGLILAISGVIWRQPQNRTPLHFKVPAVPLLPLVSIFVNVYLMMQMTAGTWARFGIWMLIGFAIYFGYGIQHSMKEVKNH----QTLPKTRAQTIDLDLTTSCVHSI-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WY07-1", "uniprot_id": "CTR3_HUMAN", "id": "Q8WY07-1", "name": "Cationic amino acid transporter 3", "aln": "----------------------------------------------------MPWQAFRRFGQKLVRRRTLESGMAETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSIVICFLVAALSSVLAGLCYAEFGARVPRSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLIGNHISKTLQGSIAL-HVPHVLAEYPDFFALGLVLLLTGLLALGASESALVTKVFTGVNLLVLGFVMISGFVKGDVHNWKLTEEDYELAMAELNDTYSLGPLGSGGFVPFGFEGILRGAATCFYAFVGFDCIATTGEEAQNPQRSIPMGIVISLSVCFLAYFAVSSALTLMMPYYQLQPESPLPEAFLYIGWAPARYVVAVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRVLARIHTGTRTPIIATVVSGIIAAFMAFLFKLTDLVDLMSIGTLLAYSLVSICVLILRYQPDQETK----------------------TGEEVELQEEAITTESEKLTLWGLFFPLNSIPTPLSGQIVYVCSSLLAVLLTALCLVLAQWSVPLLSGDLLWTAVVVLLLLLIIGIIVVIWRQPQSSTPLHFKVPALPLLPLMSIFVNIYLMMQMTAGTWARFGVWMLIGFAIYFGYGIQHSLEEIKSN----QPSRKSRAKTVDLDPGTLYVHSV-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QNI7-1", "uniprot_id": "F1QNI7_DANRE", "id": "F1QNI7-1", "name": "", "aln": "MSCSVAHFSRLLRERCSACLLSVCVRAAGSSAHHLSRGAFIFIPVSSTSSSIMTKNKLASFGKMLLRRRVLDDSPVESHFARCLTTLDLIALGVGATLGAGVYVLAGEVAREKAGPAIVLSFLIAALSSVLAGLCYAEFGARVPKTGSAYVYSYVTVGEIWAFITGWNLILSYVIGTASVARAWSATFDSLLAQKISTFFKAFMSFPDTQNVLAKYPDVFALILVMLLTGLLAFGVSESALVNKIFTGINLVVLTFVIISGFVKGDTANWNLTVEDYINRTNITGAQKIEKEFGSGGFAPFGLNGVLSGAATCFYAFVGFDCIATTSEEAKNPMRSIPIGIVASLLICFFAYFGVSAALTLMMPYYMLDKHSPLPQAFDYVGWGPARYIVSVGSLCALSTSLLGSMFPMPRVIYAMAEDGLLFRFLSRMHKKTKTPALATLVSGIVAALMAFLFDLDALVDLMSIGTLLAYTLVAVCVLILRYQPSRLGSSGADVKPVELQRLEAKAVMDVDSGDEYSQDMETIP-LKKRFSIRMLVQPICDVPTKISGIIVYSACGTISVLFTLLCLVLSVCLEQVAMGHPLFICLVVLLSVLSTVCIVVIWRQPQSKEALTFKVPLLPILPLISIFVNIYLMMQMSGATWIRFAVWMAIGFLIYFAYGIRHSSEGKNNSPQKFEPILQGKKPIYLAEDGSENEGATP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : : **: *:***.*: . *:::****:****:*****:**************::****:**:.**:******************** :****:********:*** *********************::**.*:.::** ::. : : . :***:***.*** **:******.:*.*:****.*:***:**:** **:****:**: **:** *** . :***** ***::*:* ******************.***:** ****:*** *: :**:***.**:********* *. .****:** *:** ****:*::********************:*:*********.*:::*. *: * :**:***::**:*****.* ************::**::*********.: . :* . : *:: ::::: *. *: .:** :** :** ... ::**:* *****: : *. :: :***: * *******. .* **** :*:***:*****:******:..** **.:** *** ***.***:** : :. :. : : : : : ", "identical_positions": 360, "similar_positions": 144, "identity": "51.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120813-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6ZRF8-1", "uniprot_id": "RN207_HUMAN", "id": "Q6ZRF8-1", "name": "RING finger protein 207", "aln": "MSGAIFGPLEGPSSLDAPSIHPLVCPLCHVQYERPCLLDCFHDFCAGCLRGRATDGRLTCPLCQHQTVLKGPSGLPPVDRLLQFLVDSSGDGVEAVRCANCDLECSEQDVETTYFCNTCGQPLCARCRDETHRARMFARHDIVALGQRSRDVPQKCTLHAEPYLLFSTDKKLLLCIRCFRDMQKESRAHCVDLESAYVQGCERLEQAVLAVKALQTATREAIALLQAMVEEVRHSAAEEEDAIHALFGSMQDRLAERKALLLQAVQSQYEEKDKAFKEQLSHLATLLPTLQVHLVICSSFLSLANKAEFLDLGYELMERLQGIVTRPHHLRPIQSSKIASDHRAEFARCLEPLLLLGPRRVAAAASGANTLAGGLGPKALTGPHCPSPVGKMSGSPVQKPTLHRSISTKVLLAEGENTPFAEHCRHYEDSYRHLQAEMQSLKDQVQELHRDLTKHHSLIKAEIMGDVLHKSLQLDVQIASEHASLEGMRVVFQEIWEEAYQRVANEQEIYEAQLHDLLQLRQENAYLTTITKQITPYVRSIAKVKERLEPRFQAPVDEQSESLQNTHDDSRNNAASARNNPGSVPEKREKTSEPKGNSWAPNGLSEEPLLKNMDHHRSKQKNGGDVPTWREHPT--------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q3V3A7-1", "uniprot_id": "RN207_MOUSE", "id": "Q3V3A7-1", "name": "RING finger protein 207", "aln": "MSGAIFAPLEGLSALDAASGHPLVCPLCHGQYERPCLLDCFHDFCTGCLRGRATDGRLSCPLCQHQTLVKGPSGLPPVDRLLQFLVDSSGDGSEAVRCANCDLECSQQDAETTYFCNTCGQPLCARCREETHRARMFARHDIVALGQRSRDVIQKCTLHSEPYIMFSTDKKSLLCIRCFRDMQGESRAHCVDLESAYVQGCERLEQAVLAVKALQTATKEAIALLQSMVEEVRHSAAEEEAAIHALFGSMQDRMAERKALLLQTVQSQYEEKDKAFKEQLTHLASLLPTLQVHLVICSSFLSLASKAEFLDLGYELMERLQGIVTRPHRLRPAQSSKIASDHRAEFARCLEPLLLLGPRREVSTVGGANTLSGGSSPMVLKTPSCPSPVGKMSGSPVQKPSPHRFISTKVLLAEGEDTPFTEHCRHYEDSYRGLQVEVQNLKDQVQELHRDLTKHHSLIKAEIMGDILRRSLLLDTQIASEYASLEGRRAIFQEIWEDSYQRVATQQEIYEAQLRDLLQLRQENAYLTIVTKQITPYIRSIARVKERLEPRFQVPVDEHAEHGQNMYDETPG-----RTDPGCTTEKRDKASEPNGSSWSLSSLPEGPSLKNQDHLRPKLEAGDEG--WRAGSGSKGACYQA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IKW1-1", "uniprot_id": "A0A0R4IKW1_DANRE", "id": "A0A0R4IKW1-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLCLS-LSLS---------------------------------------------------------------------------------EMPFG-------RRPTFHRHICTKVLLAEGRESPFTEHCRNFEKSYRSLQTEIQRLKDEVQEMHRDLTKHHSLINTDTMNEILERCLLIDEQIASQYSAVQTQRTVFEEKWDVTFQRVTNEQEIYEAQLHDLLQLKQENSYLTTIARQIGPYILSIAKVKERLEPRFQKPENDCIDTTVKIHEDQIS-------------CKKKSCSDRDSD----SSLILPPD---------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::* * ***: *.* ::*: ** *.********.::**:****::*.*** **.*:* ***:***:***********::: *.::*.:.* :* ****:::::: *.:*:* *: ::***:.:********:*****:***:*** :::** **: ***:********** * :: : : ::: . *:.. *: ... ..* * ", "identical_positions": 106, "similar_positions": 69, "identity": "16.51%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120813-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5NDL0-1", "uniprot_id": "EOGT_RAT", "id": "Q5NDL0-1", "name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "aln": "MLMLLVFGVLLHEVPLSGQDEAHPEADRVPGEALYDYSSLRLPEEHIPFFLHSNRHVASVCREDSHCPYKKHLESLNSCWGYEKSCTPESRFGSPICSYVDLGWTDTLESAQDMFWKQADFGYARERLEEIRMFCRPESASDSSLLCSRYLQYCRATGLYLDLRNIKRNHD--RFKEDFLQGGDIGGYCKLDRHALVSEGQRK-SPLQSWFAELQGYTQLNFRPIEDAKCDIVVEKPTYFMKLDAGINMYHHFCDFLNLYLTQHINN----SFSTDVYIVMWDTSSYGYGDLFSDTWKAFTDYDVIHLKTYDSKKVCFKEAVFSLLPRMRYGLFYNTPLISGCQNTGLFRAFSQHVLHRLNISQEGPKDGKLRVTILARSTEYRKILNQNELVNALKTVSTFEVRVVDYKYRELGFLDQLRITHNTDIFIGMHGAGLTHLLFLPDWAAVFELYNCEDERCYLDLARLRGIYYITWQKPSKVFPQDKGHHPTLGEHPKFTNYSFDVEEFMYLVLQAAEHVLQHPQWP-------LKKNHDEL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BYW9-1", "uniprot_id": "EOGT_MOUSE", "id": "Q8BYW9-1", "name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "aln": "MLMLLVFGVLLHEVPLSGQDKAHSEADDAPGKALYDYSSLRLPAEHIPFFLHNNRHVASVCREDSHCPYKKHLENLNYCWGYEKSCAPEFRFGSPVCSYVDLGWTDTLESAQDMFWRQADFGYARERLGEIRTICQPERASDSSLVCSRYLQYCRATGLYLDLRNIKRNHD--RFKEDFLQGGEIGGYCKLDSHALVSEGQRK-SPLQSWFAELQGYTQLNFRPIEDAKCDIVVEKPTYFMKLDAGINMYHHFCDFLNLYLTQHVNN----SFSTDVYIVMWDTSTYGYGDLFSDTWKAFTDYDVIHLKTYDSKKVCFKEAVFSLLPRMRYGLFYNTPLISGCQNTGLFRAFSQHVLHRLNITQEGPKDGKVRVTILARSTEYRKILNQDELVNALKTVSTFEVRVVDYKYRELGFLDQLRITHNTDIFIGMHGAGLTHLLFLPDWAAVFELYNCEDERCYLDLARLRGIHYITWRKPSKVFPQDKGHHPTLGEHPKFTNYSFDVEEFMYLVLQAAEHVLQHPQWP-------FKKKHDEL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5NDL2-1", "uniprot_id": "EOGT_HUMAN", "id": "Q5NDL2-1", "name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "aln": "MLMLFVFGVLLHEVSLSGQNEAPPNTHSIPGEPLYNYASIRLPEEHIPFFLHNNRHIATVCRKDSLCPYKKHLEKLKYCWGYEKSCKPEFRFGYPVCSYVDMGWTDTLESAEDIFWKQADFGYARERLEEMHVLCQPKETSDSSLVCSRYLQYCRATNLYLDLRNIKRNHD--RFKEDFFQSGEIGGHCKLDIRTLTSEGQRK-SPLQSWFAELQSYTQLNFRPIEDAKCDIVIEKPTYFMKLDAGVNMYHHFCDFINLYITQHVNN----SFSTDVYIVMWDTSSYGYGDLFSDTWNAFTDYDVIHLKTYDSKRVCFKEAVFSLLPRMRYGLFYNTPLISGCQNTGLFRAFAQHVLHRLNITQEGPKDGKIRVTILARSTEYRKILNQNELVNALKTVSTFEVQIVDYKYRELGFLDQLRITHNTDIFIGMHGAGLTHLLFLPDWAAVFELYNCEDERCYLDLARLRGVHYITWRRQNKVFPQDKGHHPTLGEHPKFTNYSFDVEEFMYLVLQAADHVLQHPKWP-------FKKKHDEL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B2Q0-1", "uniprot_id": "A0A8M2B2Q0_DANRE", "id": "A0A8M2B2Q0-1", "name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "aln": "MLLLVALCLLCNNKTVSATDSSR--------TPQLDYNSLALPQRHIPFFLHNNKPLAKLCKEDPLCPFKDALLLRKACWGYEKSCSAEHRFSYPVCTSLDSGWANSIQAAQELFWKQADFGYVRERLNEMKTLCKPSKPADSSLKCSSHMRFCRATNLYLDLRSPRRGHE--RYKEDFLEQGEIGGHCSLNSKALEAEGTHK-SPLQSWFSELQTYSELDFHPLDDGHCDVIIDRPTVFMKLDAGVNMYHHFCDFVNLYISQHLNN----SFSRDINIVMWDTSVYGYGDLFSETWRAFTDYDIIHLKNLDSKRVCFRDAFFSLLPRMRYGLFYNTPLISDCHSEGLFRAFSQHVLHRLSVPQDGPKQGQVRVTLLARSTEYRRIINQQELINALKTVPLFEVKLVDYKYKEMPFLEQIHVTHNSDIFIGMHGAGLTHLLFLPDWAVIFELYNCQDESCYRDLARLRGVQYMTWQKRDKVFPQDKGHHPTLGEHPKFTNYTFDVEEFMRLVLLAAEHVTRHPDWR-------AKQSREEL", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VQB7-1", "uniprot_id": "EOGT_DROME", "id": "Q9VQB7-1", "name": "EGF domain-specific O-linked N-acetylglucosamine transferase", "aln": "---MPILPILIGILHLSLAEDAK---------HLDGFSLPSLPSEHLIRYLNTFPKLKQQLPTN----LTGKGTISSACWGHERDCTPAGRFQTPQCPGEHTGWARSKEAQVRTFYNQADFGYIQEQLSQLTPQCVPTYLGDSSLECTHYLRFCRGRNLLFDFRGLEQREERIRYHMDVLGPGQLLGHCKLNRTRLSGEMEHIGSALQSWGPELRNFDVLPHPVLESGLCDVVVNTPTFIMKIDATYNMYHHFCDFFNLYASLFVNQSHPAAFNTDVQILIWET--YPYDSPFRDTFKAFSQRPVWTLSDVEGKRVCFKNVVLPLLPRMIFGLFYNTPIIQGCSNSGLFRAFSEFILHRLQIPYKPPQQ-KIRITYLSRRTKYRQVLNEDELLAPLEANDKYDVQRVSYER--LPFTNQLAITRNTDILIGMHGAGLTHLLFLPNWACIFELYNCEDPNCYKDLARLRGVRYRTWEQRDLVYPQDEGHHPEGGAHAKFTNYSFDVKEFVHLVDGAAEEILSHKEFPRRASENPSKTQRNEL", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :* :* :.: .: ** .*: :*:. : : . . ***:*:.* . ** * *. . **: : :: *:.****** :*:* :: * * .**** *: ::::**. .* :*:*. .: .: *:: *.: *:: *:*.*: * .* : *.**** .**: : * . ::.. **:::: ** :**:** *********.*** : .:*: :*. *: *::*:* * *.. * :*:.**:: : *. :.*:***::..:.***** :*******:*..* . ******::.:****.:. . *:: ::*:* *:* *:**:::*::**: .*:: ::*: *.*: : * :*: :*:*:**:***************:** :******:* ** *******: * **.: . *:***:**** * *.*****:***:**: ** **:.: * .: * .::**", "identical_positions": 200, "similar_positions": 166, "identity": "36.97%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120814-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0RBM9-1", "uniprot_id": "M0RBM9_RAT", "id": "M0RBM9-1", "name": "Rho guanine nucleotide exchange factor 10-like protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASSNPP---------PQPAIGDPLAPRAPGPSPEVEEDSGEAFEFD-----------------------------DSDDEEDTNTGLVVPG---LAPERDTEPSLICFDTVP-----------SSDLDPAAAPPQTEAPTVVSNGDA-------------------------------VGAALSGVRHSSWKRKSSRRIDRFTFP----------------ALEEDVIYDDVPCESPDAHQPGAERSLLYEDVHRAGAPREAEDLGWSSSEFESYSEDSGEETKP--EAEPTKHRGSFQPKLSPDLTRLKERYVRTKRDILALRVGGRDMQELKLKCDCKMTQLMKAAKSGTR-------DGLEKTRMAVMRKVSFLHRKDTLGDSEEEDMGLLEVGVTDIKPP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APELGPMPEGLSPQQVVRRHILGSIVQSEGSYVESLKRILQDYRNPLMEMEPKALSARKCQMVFFRVKEILHCHSMFQIALSSRVAEWDSTEKIGDLFVASFSKSMVLDVYSDYVNNFTNAMTIIKKACLTKPAFLEFLKRRQVCSTDRVTLYGLMVKPVQRFPQFILLLQDMLKNTPRGHPDRLSLQLALTELETLAEKLNEQKRLADQVAEIQQLTKSVSDRSSLNKLLTS-----------GQRQLLLCETLTETVYGDRGQLIKSKERRVFLLNDMLVCANINFKPSNHRGQLEIS---SLVPLGPKYVVKWNTALPQVQVVEVGQDGGAYDKDNLLIQHAGAKKATAAGQAQN------------------KVYLGPPRLFQELQDLQKDLAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRLMRVKEEEIHSANKCRLRLLLPGKPDKSGRPISFMVVFITPNPLSKISWVNRLHLAKIGLREENQPGWLCP-----------------------------------DEDKKSKAPFWCPILACCVPAFSSRALSLQLGGLVHSPVNSPLLGFSAVSTSLPQGYLWVGGGQEGAGGQVEIFSLNRPSPRTVKSFPLSAPVLCIEYIPDPEEEAEGAEESRATTDPSVTVHPTVCLGLQDGSILLYGSVDTGTQCLATCKSPGPQPVLCLRHGPFYLLAGLQDGTLAAYPRTSGEIPWDLESPPVCLTVGPGPIRTLLSLEDAAWASCGARVTVLDAATLQTQQSFEAHQDEAVSVTHMVKAGSGVWMAFSSGSSIRLFHTETLEHLQEINIATRTTFLLPGQK------HLCVTSLLICQGLLWVGTDQGVIVLLPVPRLEGIPKITGKGMVSLNGHCGPVAFLAVAMSILAPD--------------------------------------ILRSD--QEEAEGPQAEEDKPDGQAHETVPAPDSHTARELTRK--------------------------------------------------------------------------------------------------------------KGILLQYRLRSTAHLP---------------------------------GPLLSVREPAPADG-------------------SALEHSEEDGSIYEMADDPDVWVRS-----------------------RPCARD-AHRKEICSVAIISGGQ------------------------------GYRHFGSAPGGLSGRPAPCSETDSTLLIWQVPLAL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AWP8-1", "uniprot_id": "ARGAL_MOUSE", "id": "A2AWP8-1", "name": "Rho guanine nucleotide exchange factor 10-like protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASSNPP---------PQPAIGAPLAPSAPGPSPEVEEDSGEAFEFD-----------------------------DSDEEEDTSSGLVVPG---LAPERDTEPSLICFDTVP-----------GSDLDPAAAPPQTEAPTVVSNGDA-------------------------------VGAAISGVRRSSWKRKSSRRIDRFTFP----------------ALEEDVIYDDVPCESPDAHQPGAERGLVYEDVHRAGAPRETEDLGWSSSEFESYSEDSGEETKP--EAEPTKHRGSFQPKLSPDLTRLKERYVRTKRDILALRVGGRDMQELKLKCDCKMTQLMKAAKSGTR-------DGLEKTRMAVMRKVSFLHRKDVLGDSEEEDMGLLEVGVTDIKPP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APELGPMPDGLSPQQVVRRHILGSIVQSEGSYVESLKRILQDYRNPLMEMEPKALSARKCQVVFFRVKEILHCHSMFQIALSSRVAEWDSTEKIGDLFVASFSKSMVLDVYSDYVNNFTNAMSIIKKACLTKPAFLEFLKRRQVCSTDRVTLYGLMVKPVQRFPQFILLLQDMLKNTPRGHPDRLSLQLALTELETLAEKLNEQKRLADQVAEIQQLTKSVSDRSSLNKLLTS-----------GQRQLLLCETLTETVYGDRGQLIKSKERRVFLLNDMLVCANINFKPSNHRGQLEIS---SLVPLGPKYVVKWNTALPQVQVVEVGQDGGTYDKDNLLIQHAGAKKATAAGQAQN------------------KVYLGPPRLFQELQDLQKDLAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRLMRVKEEEIHSANKCRLRLLLPGKPDKSGRPISFMVVFITPNPLSKISWVNRLHLAKIGLREENQPGWLCP-----------------------------------DEDKKSKAPFWCPILACCVPAFSSRTLSLQLGGLVHSPVNSPLLGFSAVSTSLPQGYLWVGGGQEGAGGQVEIFSLNRPSPRTVKSFPVAAPVLCIEYIPDPEEEAEGAEESRAATDPSVTVHPTVCLGLQDGSILLYGSVDTGTQCLATCKSPGPQPVLCLRHSPFYLLAGLQDGTLAAYPRTSGDIPWDLESPPMCITVGPGPIRTLLSLEDAAWASCGPRVTVLDAATLQTQQSFEAHQDEAVSVTHMVKAGSGVWMAFSSGSSIRLFHTETLEHLQEINIATRTTFLLPGQK------HLCVTSLLICQGLLWVGTDQGVIVLLPVPRLEGIPKITGKGMVSLNGHCGPVAFLAVAMSILAPD--------------------------------------ILRSD--QEEAEGPQAEEDKPDGQAHETVPGPDSHTARELTRK--------------------------------------------------------------------------------------------------------------KGILLQYRLRSTAHLP---------------------------------GPLLSVREPAPADG-------------------SALEHSEEDGSIYEMADDPDVWVRS-----------------------RPCARD-AHRKEICSVAIISGGQ------------------------------GYRHFGGAPGGLSGRAAPCSETDSTLLIWQVPLAL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9HCE6-1", "uniprot_id": "ARGAL_HUMAN", "id": "Q9HCE6-1", "name": "Rho guanine nucleotide exchange factor 10-like protein", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MASSNPP---------PQPAIGDQLVPGVPGPSSEAEDDPGEAFEFD-----------------------------DSDDEEDTSAALGVPS---LAPERDTDPPLIHLDSIP-----------VTDPDPAAAPPGTGVPAWVSNGDA-------------------------------ADAAFSGARHSSWKRKSSRRIDRFTFP----------------ALEEDVIYDDVPCESPDAHQPGAERNLLYEDAHRAGAPRQAEDLGWSSSEFESYSEDSGEEAKPEVEVEPAKHRVSFQPKLSPDLTRLKERYARTKRDILALRVGGRDMQELKHKYDCKMTQLMKAAKSGTK-------DGLEKTRMAVMRKVSFLHRKDVLGDSEEEDMGLLEVSVSDIKPP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APELGPMPEGLSPQQVVRRHILGSIVQSEGSYVESLKRILQDYRNPLMEMEPKALSARKCQVVFFRVKEILHCHSMFQIALSSRVAEWDSTEKIGDLFVASFSKSMVLDVYSDYVNNFTSAMSIIKKACLTKPAFLEFLKRRQVCSPDRVTLYGLMVKPIQRFPQFILLLQDMLKNTPRGHPDRLSLQLALTELETLAEKLNEQKRLADQVAEIQQLTKSVSDRSSLNKLLTS-----------GQRQLLLCETLTETVYGDRGQLIKSKERRVFLLNDMLVCANINFKPANHRGQLEIS---SLVPLGPKYVVKWNTALPQVQVVEVGQDGGTYDKDNVLIQHSGAKKASASGQAQN------------------KVYLGPPRLFQELQDLQKDLAVVEQITLLISTLHGTYQNLNMTVAQDWCLALQRLMRVKEEEIHSANKCRLRLLLPGKPDKSGRPISFMVVFITPNPLSKISWVNRLHLAKIGLREENQPGWLCP-----------------------------------DEDKKSKAPFWCPILACCIPAFSSRALSLQLGALVHSPVNCPLLGFSAVSTSLPQGYLWVGGGQEGAGGQVEIFSLNRPSPRTVKSFPLAAPVLCMEYIPELEEEAESRDESPTVADPSATVHPTICLGLQDGSILLYSSVDTGTQCLVSCRSPGLQPVLCLRHSPFHLLAGLQDGTLAAYPRTSGGVLWDLESPPVCLTVGPGPVRTLLSLEDAVWASCGPRVTVLEATTLQPQQSFEAHQDEAVSVTHMVKAGSGVWMAFSSGTSIRLFHTETLEHLQEINIATRTTFLLPGQK------HLCVTSLLICQGLLWVGTDQGVIVLLPVPRLEGIPKITGKGMVSLNGHCGPVAFLAVATSILAPD--------------------------------------ILRSD--QEEAEGPRAEEDKPDGQAHEPMP--DSHVGRELTRK--------------------------------------------------------------------------------------------------------------KGILLQYRLRSTAHLP---------------------------------GPLLSMREPAPADG-------------------AALEHSEEDGSIYEMADDPDIWVRS-----------------------RPCARD-AHRKEICSVAIISGGQ------------------------------GYRNFGSALG-SSGRQAPCGETDSTLLIWQVPLML", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3BDR1-1", "uniprot_id": "A0A8M3BDR1_DANRE", "id": "A0A8M3BDR1-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSTVSSQQLAEDVEDNEQRKGFRCKDEISKEESRTPSGDNTSKYSELQILSSALEATQKKQSDLFQDASTSSPAGCTNTHSEKPMSTASSHQQLGEKVEDKEQREKSRCKDEIS-----------------------------KTDAGDETSTCTVWTCSSDLESTPDKQADYSSQATMTSYPVECSTINNATDSKRDQASTDSTAPEDLNEEED-------------------------------HTCTVVKIQRDTCTIKTNAGTEDFRHSPSQNAEGNVSTESEHQTAGPEVIYDDVPSED----LSSGEADLIYEDVQKE-EGLQGPNNGWSSSEFESYDEQSDSERPP------------TRSKLSPDVRRLRDRYTRTK-QELAMRLGG----------KHQVHQLMRAARSGTK-------DGLEKTKIAVMRRVSFLHKKDHSDDT-EDDTGYLDVMVSEAKHP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PAQLGPMPDGLSSQQIVRRHILSSIVQSERSYLDSLKRILQEYQRPLMEAEPRILSVRKIRPIFFRLREITQCHSMFQIALASRVAEWDSCEKIGDLFVASFSKSMVLDVYSDYVNNFTNAMALIKKACLSKPAFLEFLKRKQASSVDRITLYGLMVKPIQRFPQFILLLQDMLKNTPTGHVDRLPLQLALTELETLAEKLNEQKRVADQITETQQLARCVSDRS-LSKLLNS-----------EQSSLILCETLIETVYGERGQVLKSKERKVFLFGDVLICANINVK-----GPPDIS---SLVPVGPKYTLKWSAPLQQVQVVEVGQEASQS-KD--TLYQLGSVKRPGSSFGQG------------------SIILGPPRLYHELQELQHDLSVVEQVTLLVGTLQGTYQNLNTTVAQDWCLALQRLIRIKEDQIQNANKCRLRLQVPGRPDKSGRPVSFTVVFNTPSPVSKISWANRFHLAKIALRDENTPGWFFA-----------------------------------EDDGKTKAPFWCPLLACRMPVFTSKAPEWKLEAALHNPVQCALLGFSAASTSLPQGYLWVASGADSTQGQVDIFSLNRPTPRPVKSLQMGAQVRCLEYVPEPSP----SEDAETSLHSSAEVGNTICVGLDDGSILVYGSMDSAAQCLVTLHNPEGCPVLCLKHCNNVLFAGLRDGKLMVYERHHRGGLWNQDTS-RKVTIGSHPIRTLLALENSVWASCANTVTVVNGSSLSTQR-FEVHQDPMVSVAHMVRAGGGVWMAFSEGSSIRLFHTETLEHLQEINISTPSSFYNPSQK------SMRVTSLLICQGLLWVGTAQGIIITLPVPKLEGIPKITGKGMMSFNAHCGPVDFLVALSSTLSPD--------------------------------------LLKRDSVIEGHDSGCGVEDRSDSSSQESLQQHSVSTQVDGKGKG-------------------------------------------------------------------------------------------------------------RGVLLQYRLRSTSGLP---------------------------------GRPLTARGDEASDSSL-----------------ESLEHSMEDGSIYELSDDPDMWVRG-----------------------RPCEREGVRRDRVTSVAVISGGK------------------------------GFRRLR--------EGSVTATMESTLMIWQLPLTV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "M9PHU0-1", "uniprot_id": "M9PHU0_DROME", "id": "M9PHU0-1", "name": "DH domain-containing protein", "aln": "MESLGLGSRRNNGSNSTAAPTTGQGGVVGGGGVAGKVLVHTKLKQQQQQQHSNQNYYTQQQTQLQRLKQQQQKLQQQQQQQQQQQLEAVHGGVAKQCLQFPPPPDYPPPITGGGGSPVNTTPGRRQQLPRYPDPDPDAIEICNESATLETSPYHLKQLAARHSKTLGRNLGHQPHHHHTVHLHHDYSYAYYEPGAAMRHSNVPGAVSSGGGGGGGGAGRVSSVVDTSSSSSPTAEPPPNSIRALLSKGKKNKQLVSPATLQSYQTRYHKLTTKSGMGQSENFYEEINAAALQTSSGHHLRSTVGSHSAGSLNQTLVEEELRRVQNRHHKILGELNLSVEAMLMPESPPKSIDQQPLGSGSGGSGGAEATPPQPSVSVTAASGQPPTILARLTSASADNICDSGGEAGKRTKTAPGCPGGGVEQLLTTTCGDLDSGFSGSSGASYIGSLRLSKTQHIKCARQTPTVGTQSCRSFQRAATVYDEAGMSGGGGQSGSSFLTRASCGRRILSCARIRAAEDPGPNHRIAGGNGIQTVQTTATESKARSFWSRKGWRKLPGFSTSTSSINDTGLSDEHKLNSGSWEDTLDEPHHHHAHHSHHQQHLHQHHSHLSQRHQQQQQQQQQLQQTSFIGSPPSSASITTAQLHSAFSRRIAEQRERDQRDQRDQREAVGCTAATIAGGSFSANGGQAAVGVGVGSSSSCGSSSERDTKSPCRERDRNLERDRDRERDKNDDLGEEEVLTEEEQTSSSVSSLSAGNQRNSQLRSTFNKAKQHLSFDKWRTAATGSATGSASGPGSSATDSNNAASNMIMRRASACTMPSSGGGGGAGVGSSQREEATTPGESPGGRLSRWFSIRRGSSHQYDVGGRDGRHSTASSFDTPDSGSGNSPKNGSNAVAGTGGAGSQGVALDAASPQKLANLGASKMMPGVPESEDDEATANRFDVDLMMTPGSRANGTARTAHNRLIVPMLPPAPAGLSQQQLKRRHIVAAIVHSENSYVATLQRLVNDYKKPLEECSPPVLNPVKIATLFHCLPDILHSHKLFRISLAECVRNWDRDEKIGDCFVSAFGKPQLLEIYSGFINNFSAAMELAKMEEKRKSALADFFKVKQISAHDRLSFFGLMVKPVQRFPQFILFLQDLLKYTPQGHHDRMSLQLALSQLELLAELLNESKREAEQYQAFKEMLGHISGTFNARSLSLSSVSVSDSAGGHRPRYLLREDNVTHMEFNQAGFIVKCKQRRLLLLNDKVICVSVAPKQSHDFGATEKLTFKWMFPVNDVEIVDNSTSATLSRILTAGLNRGGSLKSNGSSGANGSPYANSTLPGHGGGVSGFSGFGDPHSSPAAQLTNGADNLCSEMSTLMYDYEVISRIQDLVSSLKGSYKELNANTTRNVLNLIQGSIQRKDEEMAWVDSCCLQLIGRHKSGKEE-----TFTFQTQTPAVKKEWITELRLAQLALDPNNSPAWERGGSHPQPAHHHPHHHPLQHPHAGAGDPRQTQEQLQLQEAVQQKQSRKMPLFVKAMPVYKSQHQTEVRCGCYYSIANDTKQSGNARRRHKQLNYLWMCS----SDGTSSHITVLAQHPQQAGNLREAGAFDLFETQVSALEFVKGLDQLKSRDEPASLLGDLVWLGTDSRKILIYSARNPEQEEQLGSYSVPG-AVQRILYHFDAVYVALSGATVLIFRRGNDGVWQLRDPQTIRLGDTDLVVPSLLPINMCIYASCGNRVYVMNALNGEIQRSFEVQHGATQQVNLMAHSGIGLWISLKNSTMLCLYHTETFKHLQDINIASSVLRHDGKKEQPLNNSSVYVTALMACKGLLWVGTNVGIAVTIPLPRLEGVPIISGGINMSCHAHFGPITFLLPLIPKVYPAYKPPTVGAAPLVPSMGDDLQLPAIDADPKIQELDDGAVVLRRDLAKEEMSSSNPGADSTASSPRSSKLDKQNSLDQSFTAKIRASLANSPAFHRKRFRDDPNRMSKTLPRGLGAAAAGSGAGGASAAGSGTASGNTSQHGEHGICDVYGLYGKLIFVKEDYDAEEGNQGNLMDMMYEGMRRSDPELAAIPGKVCTLDRRLRMKASRPRSLDLSNWSVDSKSSSLYTSSGSEESMGIRHFGGRSVSRNSSSASHKTSGTGSDLGNISENGLMTTADIHHHQQQQQQLNSSAKPDEMSRLGAGNSGLDKPAAAVATLKRKQKQNSKQQQQQNADGPRTVITLMGGRGYWRQMWYNGAGGSPSHKNSSSGGGGGSGSGFSGQTMQSGNPSCSPLTANSNDAHIVVWEKKL--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.. * .: . .. . . * . .: * . . . * . . :.. . : :. . * * . : : *: . . :.. : : : ..:.* . .* . . : : . * :: * . ... . . ::. .*: .**: : : . * .:: : : . . .: . : : . . * * * *** **: ****:.:**:** **: :*:*::::*:.** * .* *. * :*. : :* :.*.:*:*:*:. * :** ***** **::*.*. :*::**.::***: ** : * *.*: :*:* :* .: **::::******:********:***:** ** ** **:.*****::** *** ***.** *:* ::: :*. .* * *: :.: . :.: * ::*.*:*:::*:.* ::*..: * * : :.*:. :. .:. ::: .* : . *. *: .: .:. .: *. .* *:. * * *:.:: *:.:*:*:*::** ..::: :* :: *:::: .:.* *:* :..*. ..* * .* * .* ..::**::.* :* *.* :: : * . *::. :*.:.*: . :. .: . . .* .***: . : * . ::: *: . .: .. . :* . :: : ..: : : :* :. .**:*.: :. : . .* : : : ..* ...: : * :. : : :**.:: . :***. * *::. . . *: **.::. .* *.::* *:*:::...: : *:****::***:***:: :: : **:*: *:******* *: : :*:*:***:* *:* :* :.* **: ** . : * :*: * * .. * . ...:.. . . . * : *: *** .: * * :: . .:. :.* :: . : : .** * .. :: . . :* : **: *: :: :::*: * ", "identical_positions": 257, "similar_positions": 416, "identity": "11.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120816-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9CQW3-1", "uniprot_id": "PROZ_MOUSE", "id": "Q9CQW3-1", "name": "Vitamin K-dependent protein Z", "aln": "--MAGCILLLRGFILTLILHQVELSVFLPAPKANNVLRRWRRGSSYFLEEIFQGNLEKECYEEVCNYEEAREVFENDVITDEFWRQYGGGSPCVSQPCLNNGTCEDHIRSYSCTCSPGYEGKTCAMAKNECHLERTDGCQHFCHPGQSSYMCSCAKGYKLGKDQKSCGPSDKCACGALTSEHIRMTKSSQSQPSFPWQVRLTNSEGEDFCAGVLLQEDFVLTTAKCSLLHSNISVKANVDQR------IRIKSTHVHMRYDEESGENDVSLLQLEEPLQCPSSGLPVCVPERDFAEHVLIPGTEGLLSGWMLNGTHLATTPMLLSVTQADGEECGQTLNVTVTTRTSCEK---GSVVMGPWVEGSVVTREHKGTWFLTGILGSPPPPGQSQMLLLTAVPRYSMWFKQIMK-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P22891-1", "uniprot_id": "PROZ_HUMAN", "id": "P22891-1", "name": "Vitamin K-dependent protein Z", "aln": "--MAGCVPLLQGLVLVLALHRVEPSVFLPASKANDVLVRWKRAGSYLLEELFEGNLEKECYEEICVYEEAREVFENEVVTDEFWRRYKGGSPCISQPCLHNGSCQDSIWGYTCTCSPGYEGSNCELAKNECHPERTDGCQHFCLPGQESYTCSCAQGYRLGEDHKQCVPHDQCACGVLTSE-----KRAPDLQDLPWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITVKTYFNRTSQDPLMIKITHVHVHMRYDADAGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRTRGLLSGWARNGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCER---SSVAAMHWMDGSVVTREHRGSWFLTGVLGSQPVGGQAHMVLVTKVSRYSLWFKQIMN-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QZU6-1", "uniprot_id": "F1QZU6_DANRE", "id": "F1QZU6-1", "name": "", "aln": "MESLVYRLLFFMLITHHVSSGDQRTVFRSRRRANALLLRSRRANTFLLEEILQGNLERECYEEKCSKEEARECFENDQKTNEFWAKYYDGDQCRSNPCQHGGTCKDGIGRYTCTCAEAYSGHDCQTDKSQCPSAGPLACEHFCRPSTAAYRCFCARGYTLNSDGRSCSPNVQNPCGTTEMS------SFCPDGRCSWEVRFLNASGHDVCHGVILGQKSILTSATCMTALQDLHFTVAVGVS---TAAVRVSSWTPHKRFLSGP-DDDLCFLELQEPFPPNISTVPLCLPEKDYSENILMRAGR----------EGVAEGGATYSYLSLDDCRDALNLTFVMTNKMFCMKRESAGSERCTVSSGSPAATLEGKTAFLTGVSLSAGRCG--DTLLFTKLSRYLHWLRPLLLASEREQP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: :: : :** . :** :* * :*..:::***:::****:***** * ***** ***: *:*** :* .*. * *:** :.*:*:* * *:***: .*.* * *.:* . .*:*** *. :* * **:** *..* :.* * : .**. . .*:*:: *:.*.*.* **:: :. :**:*.* :: ... .. :::. * *: . ::*:.:*:*: *: : :*:* **:*::*::*: . :. . :. . . *...:*.: * : .. .** .: . : ****: * * . :*.* :.** *:: :: ", "identical_positions": 110, "similar_positions": 125, "identity": "26.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120817-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5FVN1-1", "uniprot_id": "STBD1_RAT", "id": "Q5FVN1-1", "name": "Starch-binding domain-containing protein 1", "aln": "--------------------MGAVWSALLVG--GGLAGALILWLLRGDSGAPGKDGGAEP-LKDAPPGEAAAP-----------------------------GGGPGGGGSGGLSPEPSDREL------------------------------------VSKAEHLRESNGHLISESKDLG---NLTEA-QRLQNVG-------NAREYVPVGKVPDTHSRANSETS---------RNQSPESRVG-----------------------------EWRLPKGHETAVKVAGSVAEKLPSS-------------------------------------------------SPLMDRAEAAS------LAQSAGHEDWEVVSRHSSWGSVGLGGSLEASRLSLNQGMDESRNSLVGG-GWEVDGKVVSVK-----PRQVSIQFKVHYSTSTDVQFIAVTGDHESLGGWNTYIPLHYCKDGLWSHSVFLPADTVVEWKFVLVENKEVTRWEECSNRRLQTG--HEDKVVHGWWGIH", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C7E7-1", "uniprot_id": "STBD1_MOUSE", "id": "Q8C7E7-1", "name": "Starch-binding domain-containing protein 1", "aln": "--------------------MGAVWSALLVG--GGLAGALILWLLRGDSGAPGKDGVAEPPQKGAPPGEAAAP-----------------------------GDGPGGGGSGGLSPEPSDREL------------------------------------VSKAEHLRESNGHLISESKDLG---NLPEA-QRLQNVGADWV---NAREFVPVGKIPDTHSRADSEAA---------RNQSPGSHGG-----------------------------EWRLPKGQETAVKVAGSVAAKLPSS-------------------------------------------------SLLVDRAKAVS------QDQ-AGHEDWEVVSRHSSWGSVGLGGSLEASRLSLNQRMDDSTNSLVGGRGWEVDGKVASLK-----PQQVSIQFQVHYTTNTDVQFIAVTGDHESLGRWNTYIPLHYCKDGLWSHSVFLPADTVVEWKFVLVENKEVTRWEECSNRFLQTG--HEDKVVHGWWGIH", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95210-1", "uniprot_id": "STBD1_HUMAN", "id": "O95210-1", "name": "Starch-binding domain-containing protein 1", "aln": "--------------------MGAVWSALLVG--GGLAGALFVWLLRGGPGDTGKDGDAEQ-EKDAPLGGAAIP-----------------------------GGHQSG--SSGLSPGPSGQEL------------------------------------VTKPEHLQESNGHLISKTKDLG---KLQAASWRLQNPSREVCD--NSREHVPSGQFPDTEAPATSETSNSRSYSEVSRNESLESPMG-----------------------------EWGFQKGQEISAKAATCFAEKLPSS-------------------------------------------------NLLKNRAKEEMSLSDLNSQDRVDHEEWEMVPRHSSWGDVGVGGSLKAPVLNLNQGMDNGRSTLVEARGQQVHGKMERVAVMPAGSQQVSVRFQVHYVTSTDVQFIAVTGDHECLGRWNTYIPLHYNKDGFWSHSIFLPADTVVEWKFVLVENGGVTRWEECSNRFLETG--HEDKVVHAWWGIH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PYN9-1", "uniprot_id": "A0A8M1PYN9_DANRE", "id": "A0A8M1PYN9-1", "name": "Starch-binding domain-containing protein 1", "aln": "MKKSQPIALDGRDIQSLLDAVGGFGSVVAVGIIAMLSVCAAFFIYRSFRGQRGKTDEINGKETTVATGEESAVRRRRTEKDDRPTESTAECQDAKQKKHRSESSYSSATNNIPLPTEAAEKDLNESTLKDLEEITDELLTDLEPEMGDKTDSDFDPCMEIDPDENTECEEDHIRLKENDDGGCEVVADACVRLTQLDCQIEKTEEFLDKPEGGQSLDTDEPSETESAQDIVYQRRQDTLHNSSSCQSVDHKPSKNHLEEDIKTAEEACKKFEDHHDWRFARTNNFDCCCCDKKMERMKGQPWFPIGSYATDTFTPTVETMVNHCSRFDFQNYLGFQTDNTFIGVSSTQMSLSQEKKANEEGATVEVKHEKNQISIMDAIMDNNEWLNVGAPEFKDRPWLTPNASINEEGKPKADLAKDEEELANKRVATVPPLAQTVSVTFRIHYITHSALQLVAVTGSLQELGAWESFIPLQRAKDGFWANTVSLPVESQVEWKFVLVEDGRISRWEECGNRYLCLTSQDEEVFLEKCWGCC", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :*.. *.: ** . *: . .:: *. * ** . : . .. * : .. .. . *.. .: ::* : *: . .:.*: : :* * : * ** : . : : *: **. : :*:: . * :* : : :: . :: .. . :: : . : : :..* .** . . *. * ::: .. . : . : .: **: *::** * : :*::****. : ** *:::***: ***:*:::: **.:: *********: ::*****.** * .*: .:. ** ", "identical_positions": 73, "similar_positions": 115, "identity": "13.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120823-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P47739-1", "uniprot_id": "AL3A1_MOUSE", "id": "P47739-1", "name": "Aldehyde dehydrogenase, dimeric NADP-preferring", "aln": "------------------------------------------------------------------MSNISSIVNRARDAFNSGKTRPLQFRVEQLEALQRMINENLKGISKALASNLRKNEWTSYYEEVAHVLDEIDFTIKGLSDWAEDEPVAKT-RQTQEDDLYIHSEPLGVVLVIGAWNYPFNLTIQPMVGAIAAGNAVVLKPSEVSDHMADLLSTLIPQY-MDKDLYPVIKGGVPETTELLKE-KFDHIMYTGSTAVGKIVMAAAAKHLTPVTLELGGKSPCYVDK---DCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNEIVEKLKKSLKDFYGEDAKQSHDYGRIINDRHFQRVINLIDSKK-------VAHGGTWDQPSRYIAPTILVDVDPQSPVMQEEIFGPVMPIVCVRSLDEAIK-FINQREKPLALYVFSNNDKVIKKMIAETSSGGVTANDVIVHITVPTLPFGGVGNSGMGAYHGKKSFETFSHRRSCLVRSLR--NEEANKARYPP-SPAKMPRH---------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30838-1", "uniprot_id": "AL3A1_HUMAN", "id": "P30838-1", "name": "Aldehyde dehydrogenase, dimeric NADP-preferring", "aln": "------------------------------------------------------------------MSKISEAVKRARAAFSSGRTRPLQFRIQQLEALQRLIQEQEQELVGALAADLHKNEWNAYYEEVVYVLEEIEYMIQKLPEWAADEPVEKT-PQTQQDELYIHSEPLGVVLVIGTWNYPFNLTIQPMVGAIAAGNSVVLKPSELSENMASLLATIIPQY-LDKDLYPVINGGVPETTELLKE-RFDHILYTGSTGVGKIIMTAAAKHLTPVTLELGGKSPCYVDK---NCDLDVACRRIAWGKFMNSGQTCVAPDYILCDPSIQNQIVEKLKKSLKEFYGEDAKKSRDYGRIISARHFQRVMGLIEGQK-------VAYGGTGDAATRYIAPTILTDVDPQSPVMQEEIFGPVLPIVCVRSLEEAIQ-FINQREKPLALYMFSSNDKVIKKMIAETSSGGVAANDVIVHITLHSLPFGGVGNSGMGSYHGKKSFETFSHRRSCLVRPLM--NDEGLKVRYPP-SPAKMTQH---------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P47740-1", "uniprot_id": "AL3A2_MOUSE", "id": "P47740-1", "name": "Aldehyde dehydrogenase family 3 member A2", "aln": "---------------------------------------------------------------------MERQVLRLRQAFRSGRSRPLRFRLQQLEALRRMVQEREKEILAAIAADLSKSELNAYSHEVITILGEIDFMLGNLPELASARPAKKN-LLTMMDEAYVQPEPLGVVLIIGAWNYPFVLTMQPLVGAIAAGNAAIVKPSELSENTAKILAELLPQY-LDQDLYAIVNGGIPETTELLKQ-RFDHILYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDR---DCDLDVACRRIAWGKYMNCGQTCIAPDYILCEASLQNQIVQKIKETVKDFYGENIKASPDYERIINLRHFKRLQSLLKGQK-------IAFGGEMDEATRYLAPTILTDVDPNSKVMQEEIFGPILPIVSVKNVDEAIN-FINDREKPLALYVFSRNNKLIKRVIDETSSGGVTGNDVIMHFTVNSLPFGGVGASGMGAYHGKYSFDTFSHQRPCLLKGLK--GESVNKLRYPPNSESKVSWAKFFLLKQ------FNKGRLGMLLFVCLVAVAAVIVKDQL------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P30839-1", "uniprot_id": "AL3A2_RAT", "id": "P30839-1", "name": "Aldehyde dehydrogenase family 3 member A2", "aln": "---------------------------------------------------------------------MERQVQRLRQTFRSGRSRPLRFRLQQLEALRRMVQEREKDILAAIAADLSKSELNAYSHEVITILGEIDFMLGNLPELASARPAKKN-LLTMMDEAYVQPEPLGVVLIIGAWNYPFVLTLQPLVGAIAAGNAAIVKPSELSENTAKILAELLPQY-LDQDLYMIVNGGVEETTELLRQ-RFDHILYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDR---DCDLDVACRRITWGKYMNCGQTCIAPDYILCEASSQDQIVQKIKDTVKDFYGENVKASPDYERIINLRHFKRIKSLLEGQK-------IAFGGETDEATRYIAPTILTDVDPNSKVMQEEIFGPILPIVSVKNVEEAIN-FINDREKPLALYIFSHNNKLIKRVIDETSSGGVTGNDVIMHFTVNSLPFGGVGASGMGAYHGKYSFDTFSHQRPCLLKGLK--GESVNKLRYPPNSESKVSWSKFFLLKQ------FNKGRLQLLLLVCLVAVAAVIVKDQL------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P51648-1", "uniprot_id": "AL3A2_HUMAN", "id": "P51648-1", "name": "Aldehyde dehydrogenase family 3 member A2", "aln": "---------------------------------------------------------------------MELEVRRVRQAFLSGRSRPLRFRLQQLEALRRMVQEREKDILTAIAADLCKSEFNVYSQEVITVLGEIDFMLENLPEWVTAKPVKKN-VLTMLDEAYIQPQPLGVVLIIGAWNYPFVLTIQPLIGAIAAGNAVIIKPSELSENTAKILAKLLPQY-LDQDLYIVINGGVEETTELLKQ-RFDHIFYTGNTAVGKIVMEAAAKHLTPVTLELGGKSPCYIDK---DCDLDIVCRRITWGKYMNCGQTCIAPDYILCEASLQNQIVWKIKETVKEFYGENIKESPDYERIINLRHFKRILSLLEGQK-------IAFGGETDEATRYIAPTVLTDVDPKTKVMQEEIFGPILPIVPVKNVDEAIN-FINEREKPLALYVFSHNHKLIKRMIDETSSGGVTGNDVIMHFTLNSFPFGGVGSSGMGAYHGKHSFDTFSHQRPCLLKSLK--REGANKLRYPPNSQSKVDWGKFFLLKR------FNKEKLGLLLLTFLGIVAAVLVKAEYY-----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0ACD6B720-1", "uniprot_id": "A0ACD6B720_DANRE", "id": "A0ACD6B720-1", "name": "Aldehyde dehydrogenase", "aln": "--------------------------------------------------------------------MEKQVVDGLREVFQSGRSRPLQYRKQQLRALLRLITERHADIEQALKQDLNRSMHGTSLFELIGIENDIKVAEREMTEWAAPRPVKKN-LNSALDDVYVKPEPLGVVLIIGTWNYPWAMIFQPLVGAIAAGNAAVVKPSELSEHSSRLMKELLPLY-LDKEMYQVVTGGVPETQELLKQ-RFDHIFYTGSSTVGKLVMEAASRHLTPVTLELGGKSPCYIDK---NCDIAVACRRITWGKFANCGQTCIAPDYILCEPSIQDRIVEEIQKTLLEFYQTDPKSSPDYCRIINTRHFDRVLALMNECT-------IALGGENDRSQCYIAPTVLKDVLPHFKIMQEEIFGPLLPIVTVNGLSEAIN-FINAREKPLALYVFSSDKTVIKRMLKETTSGGVTVNDVLMHYTVDTLPFGGVGNSGMGRYHGKHTFDQLSHHRACLIKSFA--MESLNDARYPPLTTARLRKAKFFMGHR------MCSCNGMCVWAVIATVLAIGLLVGLLVVLI--", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0C4DHC8-1", "uniprot_id": "A0A0C4DHC8_DROME", "id": "A0A0C4DHC8-1", "name": "", "aln": "MFDNAIKPHPEANGAPINAAGDRPITTVINIEPEPETESPIGIFTSQPESQQQQPEQLQSESESDRMANFDDTLQRARLAFSSGKTRNVSFRRKQLENLLRCYEEHENEIISALEADLRRPKQESLIVETEFMKNDIRHILFQLDEWVQSEKPPKS-FVNMMDDVQIYNDPFGVVLVIGAWNYPLQLLLVPVASAIAAGNCVVIKPSEIAANCAKFIADVIPKY-LDNDCYPVVCGGPSETAELLNQ-RFDYIFYTGSTRVGKIIHAAANKYLTPTTLELGGKSPCYIDK---SVDMRTAVKRILWGKLINCGQTCIAPDYILCSKEVQEKFIVEAKDVLKEWYGENIQSSPDLSRVINANNFQRLLGLMKSGR-------VAVGGNYDASERFIEPTILVDVKETDPIMEEEIFGPILPIFNVESAYDAIK-FINAREKPLVIYVFSNSNKLVKEFRRSTTSGGFSSNETIMHCGVDVLPFGGVGMSGMGRYHGKYGFETFTHKKSCLGKDLSPLGEKLSSARYPPYSDRKGSLLSFLLRKRRPLPNLHLSHVLAIGLGVGLTVLTNYYLQGKLLSK---", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q04458-1", "uniprot_id": "HFD1_YEAST", "id": "Q04458-1", "name": "Fatty aldehyde dehydrogenase HFD1", "aln": "-------------------------------------------MSNDGSKILNYTPVSKIDEIVEISRNFFFEKQLKLSHENNPRKKDLEFRQLQLKKLYYAVKDHEEELIDAMYKDFHRNKIESVLNETTKLMNDILHLIEILPKLIKPRRVSDSSPPFMFGKTIVEKISRGSVLIIAPFNFPLLLAFAPLAAALAAGNTIVLKPSELTPHTAVVMENLLTTAGFPDGLIQVVQGAIDETTRLLDCGKFDLIFYTGSPRVGSIVAEKAAKSLTPCVLELGGKSPTFITENFKASNIKIALKRIFFGAFGNSGQICVSPDYLLVHKSIYPKVIKECESVLNEFYPS-FDEQTDFTRMIHEPAYKKAVASINSTNGSKIVPSKISINSDTEDLCLVPPTIVYNIGWDDPLMKQENFAPVLPIIEYEDLDETINKIIEEHDTPLVQYIFSDSQTEINRILTRLRSGDCVVGDTVIHVGITDAPFGGIGTSGYGNYGGYYGFNTFSHERTIFKQPYWN--DFTLFMRYPPNSAQKEKLVRFAMERK---PWFDRNGNNKWGLRQYFSLSAAVILISTIYAHCSS", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . :.: : :* **. * :. : *: :: : * : :* : . . .. .. : . * **:*..:*:* : : *: .*:**** ::****:: : : .: ::. : . :: *. ** .** :** *:***.. **.:: * : *** .******** :: . :: . :** :* *.** *::***:* . ..: : :. : ::* . . * *:* :.: :. . : **:: :: :*::* *.*::**. .. ::*: :*: ::.**. *:** ... ::.. **. .:.::* : ****:* ** * * * *: ::*.:. : : : **** : : ", "identical_positions": 97, "similar_positions": 142, "identity": "16.7%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120824-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "M0R632-1", "uniprot_id": "M0R632_RAT", "id": "M0R632-1", "name": "", "aln": "--------------MTFPTKSADFAIFIHLIVFQNSQLDLLPPMLPLLGGGAEENVWSNHTLNERTIVRGGRT--------------SALTERHDQKDQFSSEKEK-------------------------------------------------------------------------------------------------------ITKLNKKNAEKT-----SGSEVQRTCVICHVERQDKIEFVQRNSTE--LREYAGTKDASCMESLEKQESNSLGYKQDTEDNNGGENGISSKEDSREIEAENRASTAASGTVLDKHSTES--------QHTEDMNGVQSHERSISNIKTISTPGILGNSASGPTLQNAEQTESTGSSKRRVAEECFLSEDNKKSRIDVVGAGEESIPRTEENRQARSLDNRLQDGMTTSREQDLAVQLDD------------VPAPAAPFDHRIVMAKHAAVDSLYSVSKSEILGGGRFGQVHKCEEKATGLKLAAKIIKIRGAKDKEDVKNEISVMNQLDHVNLIQLYDAFESKHDIILVMEYVEGGELFDRIIDENCNLTELDTILFVKQICEGIRYMHQMYILHLDLKPENILCVNRDAKQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYDFVSFATDMWSVGVITYMLLSGLSPFLGDNDAETLTNILACRWDLEDEEFQDISEEAKEFISKLLIKEKSWRISASEALKHPWLSDHKLHSRLSAQKNSNSG--VLNLTTK--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5SUV5-1", "uniprot_id": "MYLK4_MOUSE", "id": "Q5SUV5-1", "name": "Myosin light chain kinase family member 4", "aln": "-------------------------------------------------------------------------------------------------------MLK-------------------------------------------------------------------------------------------------------VKRLEEISSCHS-----SNP-------------LEKVAFFQ------------------CMEEVEKVK-------------------------------------------------------------------------------------------------------------------CFLEENS--GDLDLQSGDNE----AEEN----VWSNRALDERIIVKGGRTSALTDD------------IPAPAAPFDHRMVMAKHASVDNLYTVSKSEILGGGRFGQVHKCEEKATGLKLAAKIIKTRGAKDKEDVKNEISVMNQLDHVNLIQLYDAFESKHDIILVMD-VEGGELFDRIIDENCNLTELDTILFMKQICEGIRYMHQMYILHLDLKPENILCVNRDAKQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYDFVSFSTDMWSVGVITYMLLSGLSPFLGDNDAETLTNILACRWDLEDEEFQDISEEAKEFISKLLIKEKSWRISASEALKHPWLSDHKLHSRLSAQKNCNSG--VLNLTTK--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86YV6-1", "uniprot_id": "MYLK4_HUMAN", "id": "Q86YV6-1", "name": "Myosin light chain kinase family member 4", "aln": "-------------------------------------------------------------------------------------------------------MLK-------------------------------------------------------------------------------------------------------VKRLEEFNTCYN-----SNQ-------------LEKMAFFQ------------------CREEVEKVK-------------------------------------------------------------------------------------------------------------------CFLEKNS--GDQDSRSGHNEAK---------EVWSNADLTERMPVKSKRTSALAVD------------IPAPPAPFDHRIVTAKQGAVNSFYTVSKTEILGGGRFGQVHKCEETATGLKLAAKIIKTRGMKDKEEVKNEISVMNQLDHANLIQLYDAFESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILFMKQICEGIRHMHQMYILHLDLKPENILCVNRDAKQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYDFVSFPTDMWSVGVIAYMLLSGLSPFLGDNDAETLNNILACRWDLEDEEFQDISEEAKEFISKLLIKEKSWRISASEALKHPWLSDHKLHSRLNAQKKKNRGSDAQDFVTK--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TBH3-1", "uniprot_id": "A0A8N7TBH3_DANRE", "id": "A0A8N7TBH3-1", "name": "", "aln": "MSSADANTGMDLLQVRIESLSSKMDRLISIQEKVLSRLDGMSQDIDGIERDVETLKVEKEEIHFPPVIRTGTGNQMKEMCEEMNSIMLAVNQRSEQQTQKLEGMEKLVMSIQQAVSFIGETVKTSKIMDIMFKGPASRKSKSAPGLKSKDSKIKPSSKCENSEAVSAKLKEPKGFHLSLKGLKAQRKKKPPDSAADKVFLRKQALLLEEVQKLNQENAERSKPAQTQDNDLQKSEDASVTPHLQDIILEEAKPVEDEPRKKTKVEKKVTLDLREEQKNIPETNTEEIREEMKKADTEEILLKTTEVLKDQKTDDTESKTTTEGPSEADNIDTKATEGPSEDVITDKETIEGPSEADITDTEPPTATENSEISSESEQADEVTTSSKRRVTEEDLGLEDHKKSRVE-DGEQQEPEPPEPEDLRAVFKADGVEIQIDFSKLKQQSFEDEDDEDHGDHFFIDCTPPPAAPFNHRVVSAKPHQISTFYTINQQEVLGGGRYGQVHKCIENSSGLTLAAKIIKAKSQKEKEVVKNEIQVMNQLDHANLIQLYAAYESRNDIILVLEYVDGGELFDRIIDENYKLTELDTVMFIRQICEGLRYMHKMYILHLDLKPENILCVSRVTNKVKIIDFGLARKYQPREKLRVNFGTPEFLSPEVVNYDFVSFNTDMWSLGVITYMLLSGLSPFLGDDDNETLNNILACQWNFEEDEFSEVSAEAKDFISKLLVVDKSWRIGATEALRHPWLSDAAVHFRLHERKNKCRSRRNSCLPPPES", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : :*:: .: . .. :.: : : : *: : : :: . : . :* : : : * *.*.***:**:* ** :..:*::.: *:*****:****** *.::**.******* :. *:** *****.*******.****** *:**::**:**:: *:***********. :******::*::*****:*:**:****************.* ::::*********:*:*****:*********:*********** *****:***:*************:* ***.*****:*::*::**.::* ***:******: :*****.*:***:****** :* ** :*: . : . ", "identical_positions": 208, "similar_positions": 99, "identity": "27.01%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120827-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q02930-1", "uniprot_id": "CREB5_HUMAN", "id": "Q02930-1", "name": "Cyclic AMP-responsive element-binding protein 5", "aln": "MIYEESKMNLEQERPFVCSAPGCSQRFPTEDHLMIHRHKHEMTLKFPSIKTDNMLSDQTPTPTRFLKNCEEVGLFSELDCSLEHEFRKAQEEESSKRNISMHNAVGGAMTGPGTHQLSSARLPNHDTNVVIQQAMPSPQSSSVITQAPSTNRQIGPVPGSLSSLLHLHNRQRQPMP----ASMPGTLPNPTMPGSSAVLMP-----------MERQMSVNSSIMGMQGPNLSNPCASPQVQPMHSEAKMRLKAALTHHPAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHTGNQAQVSPATQQMQPTQTIQPPQPTGGRRRRVVDEDPDERRRKFLERNRAAATRCRQKRKVWVMSLEKKAEELTQTNMQLQNEVSMLKNEVAQLKQLLLTHKDCPITAMQKESQGYLSPESSPPASPVPACSQQQVIQHNTITTSSSVSEVVGSSTLSQLTTHRTDLNPIL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8K1L0-1", "uniprot_id": "CREB5_MOUSE", "id": "Q8K1L0-1", "name": "Cyclic AMP-responsive element-binding protein 5", "aln": "--------------------------------------------------------------------------------------------------MSMR-----------------------------------------------------PVPGSLSSLLHLHNRQRQPMP----ASMPGTLPNPTMPGSSAVLMP-----------MERQMSVNSSIMGMQGPNLSNPCASPQVQPMHSEAKMRLKAALTHHPAAMSNGNMSTIGHMMEMMGSRQDQTPHHHLHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQTSPHPPLHTGNQAQVSPATQQMQPTQTIQPPQPTGGRRRRVVDEDPDERRRKFLERNRAAATRCRQKRKVWVMSLEKKAEELTQTNMQLQNEVSMLKNEVAQLKQLLLTHKDCPITAMQKESQGYLSPESSPPASPVPACSQQQVIQHNTITTSSSVSEVVGSSTLSQLTTHRTDLNPIL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IL04-1", "uniprot_id": "A0A0R4IL04_DANRE", "id": "A0A0R4IL04-1", "name": "Cyclic AMP-responsive element-binding protein 5", "aln": "------MMNVDQDRPFVCIAPGCSQSFQREDHLIIHRHKHEMTLKFPSIKCDSMLSDQTPTPTRFLRDCEEVGLFTDLELN------QSQTEEQTKPNFSAQTSAQR-------------------------------QPHTETQPEQGQHQQFQPQQQQSCALAHLNQNQLQTHSSQCQSQCTATYSSSNKQSAPSCLHSRQTNTVKSNMNMESQMSMNSSIIGIPGPAHSGSCSSVQ----------RSKVIPAHSQPAVSNGSQNPLCHMMEMMPSQ--PHPLSHLQSASHHHASY-QQHCHSQSPQRLAHQHQSQDQSHHSHAHHSTPSHLPLGPSHQNAPPLS--HQPIPIQMSSTPKQSHCPQ--SPPQPATGRRRRTAEDDPDERRRKFLERNRAAATRCRQKRKVWVSSLERKAEELTHTNLQLQNEVTSLRTEVTQLKQILLTHKDCPVSVRQRETQSGIG---SPTGSPV----HSHAIQHNSISTSSTLPR--GHLTTHSHSTSNTQL----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* : * . .:* **::.* *. . :. ..* .... .:.: * . ** ***:****:*: ** *..*:* * * *. :* .*:***. ..: ****** *: * *::* .*:* : :* :.:. *: **: :.* : ::.*.** : *** *:*:::.* . * *:*.:.:* : .* .****: *****..::**************************** ***:******:**:******: *:.**:****:********::. *:*:*. :. **..*** :.:.****:*:***::.. * * . :* .*:* ", "identical_positions": 153, "similar_positions": 109, "identity": "29.25%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120906-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q4KM31-1", "uniprot_id": "LIMD2_RAT", "id": "Q4KM31-1", "name": "LIM domain-containing protein 2", "aln": "MF-----QAAGAAQATPSHE-----------------AKGSSGNSTVQRSKSFSLRAQVKETCAACQKTVYPMERLVADKLIFHNSCFCCKHCHTKLSLGSYAAMHGEFYCKPHFQQLFKSKGNYDEGFGRKQHKELWAHKEVDSGTKTA", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BGB5-1", "uniprot_id": "LIMD2_MOUSE", "id": "Q8BGB5-1", "name": "LIM domain-containing protein 2", "aln": "MF-----QAAGAAQATPSHE-----------------AKGSSGSSTVQRSKSFSLRAQVKETCAACQKTVYPMERLVADKLIFHNSCFCCKHCHTKLSLGSYAAMHGEFYCRPHFQQLFKSKGNYDEGFGRKQHKELWAHKEVDSGTKTA", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BT23-1", "uniprot_id": "LIMD2_HUMAN", "id": "Q9BT23-1", "name": "LIM domain-containing protein 2", "aln": "MF-----QAAGAAQATPSHD-----------------AKGG-GSSTVQRSKSFSLRAQVKETCAACQKTVYPMERLVADKLIFHNSCFCCKHCHTKLSLGSYAALHGEFYCKPHFQQLFKSKGNYDEGFGRKQHKELWAHKEVDPGTKTA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M3AQP1-1", "uniprot_id": "A0A8M3AQP1_DANRE", "id": "A0A8M3AQP1-1", "name": "", "aln": "MFVLVAAQTKGACESIQQMEGFRRDWRKCSEGSIFEDNRNTSDEKPVQRSKSFSFKTQ-KETCASCEKTVYPMERLVANNLIFHAACFCCKHCNTKLSLGSYAALQGEFYCKPHFQQLFKSKGNYDEGFGRKQHKELWASKDAESIGKTA", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *: **.:: . : :. ....********:::* *****:*:***********::**** :*******:**********::*****:*************************** *:.:. ***", "identical_positions": 88, "similar_positions": 28, "identity": "58.67%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120907-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N143-1", "uniprot_id": "BCL6B_HUMAN", "id": "Q8N143-1", "name": "B-cell CLL/lymphoma 6 member B protein", "aln": "----MGSPAAPEG---ALGYVREFTRHSSDVLGNLNELRLRGILTDVTLLVGGQPLRAHKAVLIACSGFFYSIFRGRAG--VGVD--VLSLPGGPEARGFAPLLDFMYTSRLRLSPATAPAVLAAATYLQMEHVVQACHRFIQASY--------------EPLG-----------------------------------ISLRPLEAEPPTPPTAP--------PPGSPRRSEGHPDPPTESRSCSQG------PPSPASPDPKACNWKKYKYIVLNSQASQAGSLVGERSSGQPCPQARLPSGDEASSSSSSSSSSSEEGPIPGPQSR--LSPTAATVQFKCGAPASTPYLLTSQAQDTSGSPSERARPLPGSEFFSCQNCEAVAGCSSGLDSLVPGDEDKPYKCQLCRSSFRYKGNLASHR-TVHTGEKPYHCSICGARFNRPANLKTHSRIHSGEKPYKCETCGSRFVQVAHLRAHVLIHTGEKPYPCPTCGTRFRHLQTLKSHVRIHTGEKPYHCDPCGLHFRHKSQLRLHLRQKHGAATNTKVHYHILGGP-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O88282-1", "uniprot_id": "BCL6B_MOUSE", "id": "O88282-1", "name": "B-cell CLL/lymphoma 6 member B protein", "aln": "----MGSTAAPEG---ALGYVREFTRHSSDVLSNLNELRLRGILTDVTLLVGGQPLRAHKAVLIACSGFFYSIFRGRAG--LGVD--VLSLPGGPEARGFAPLLDFMYTSRLRLSPATAPAVLAAATYLQMEHVVQACHRFIQASY--------------EPLG-----------------------------------ISLRPVEVEPPRPPTVA--------PPGSPRRSEGHPDPPTESRSCSQG------SPSPASPDPKACNWKKYKFIVLNSQTSQAGSLVGE-SSGQPCPQARLPSGDEACSSSSSS----EEGTTPGLQSR--LSLATTTARFKCGALANNSYLFTPRAQETSLPASKQANPPPGSEFFSCQNCEAVAGCSSGLELLAPGDEDKPYKCQLCRSAFRYKGNLASHR-TVHTGEKPYRCSICGARFNRPANLKTHSRIHSGEKPYKCETCGSRFVQVAHLRAHVLIHTGEKPYPCPTCGTRFRHLQTLKSHVRIHTGEKPYHCDPCGLHFRHKSQLRLHLRQKHGAATNTKVRYHILGGP-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1PRU8-1", "uniprot_id": "A0A8M1PRU8_DANRE", "id": "A0A8M1PRU8-1", "name": "", "aln": "MEEEHRSPFAAAHVMEMKGYVKEFTRHSNDVLLNLNELRHRDILTDATLLVGTTKLRAHCAVLIACSGFFYTLFSRRVAGICGEQGFSLTLPEGLDAGSVSLLLDFMYTSCLPLTPRTVPGVLTAATYLQMEHVADTCRAFIQHSEGISASPSLMEPVFRTALGGRSPPAHPTVFSPSRPTAEAEDPIPDRARIPDESFASLDPGTCQTPIPKTQTKLEDSSPCTPDSPSQSSGQPNSPAESSGCSLSPQLKKRSESKLTPDPKACNWKKYKYIVLNPLCATPIKEEGPEEDRHSQNHAPFTSDRMEAASKTTN--NIWNGEEAGLNDRKILSLPYNTSQQKISFAPRHVVEHTLQPLSLSISGDQ--------GLCSPYVCSQIANQGHLLG-------QHPIKFENLSTQLSYIGNQGTHTKPSSSGDKPYRCNICGAQFNRPANLKTHSRIHSGEKPYRCDTCGARFVQVAHLRAHVLIHTGEKPYPCNTCGTRFRHLQTLKSHLRIHTGEKPYSCEKCHLHFRHKSQLRLHLRQKHGAITNTKIRYKVLADPYQPAPALLQAC", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0ABK0M744-1", "uniprot_id": "A0ABK0M744_RAT", "id": "A0ABK0M744-1", "name": "Monocarboxylate transporter 13", "aln": "---MVHRTEPPDG---GWGWMVVLSAFFQSALVFG---VLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFGSPIG------------------------------SALSTKLGPRPVVMTGGILAALGMLLASFATSLTHLY--------------LSIG------------------------------------LLSGSGWALTFTPTLA-----------------CLSRYFSQRRSLAMG-------LALTGVGISSFAFAPLFQWLLNNYAWRGALLLVSALSLHLVACGALLRPLSLTEDTAVG------GPWAQITSL---LCHGPFLRYTVALTLINTGYFIPYVHLVAHLQDLGWDPLPAAFLLSVAAISDLVG----------------------RVASGWLGDAVPGP---VARLLMLWTTLTGVSLALFPVAQASTTLVVLAVAYGFTSG--ALTPVAFSVIPELVGTGR-----IYCG--LGLVQMIESVGGLLG--APLSGKENRVADWAGHVMVSSWGKEPGWCMLIVPSSM----------------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. *:: :: . ...* *.: . . :*. :* . **. *: * . * * . . * *::.. : : : : .:* * . . * . . :: . : . : . .: : :** . : . : ..: . * . . : . . : . : * . :.. : *: . : .: *. : . :: : : .* : :. **. *: **. ** : :* ::* : * . : : :: * ", "identical_positions": 34, "similar_positions": 99, "identity": "6.0%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120907-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5NC32-1", "uniprot_id": "MOT11_MOUSE", "id": "Q5NC32-1", "name": "Monocarboxylate transporter 11", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTPKPAG---------PPDGGWGWVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFERSAQ---DTAWVSALALAVQQAASPVGSALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLGLLAGSGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLGAVTLHLTPCGALLRPLALSG----------------------------------------------------------------------------------------------DPLAP-PRTPLAALG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LGLFKRRAFSVFALGTALIGGGYFVPYVHLGPHALDQGMGGYGAALVVAVAAVGDACARLASGWLADQGWVPLPRLLVVFGSLTGLGVLAMGLVPTVGTEEGWGAPLLAAAGAYGLSAGSYAPLVFGVLPGLVGIGGVVQATG----LVMMLMSLGGLLGPPLSGFLRDKTGDFSASFLVCSSFILSGSFIYMGLPRALPSCRPASPPATPP-----PERGELLPVPQVS-----------LLS-----------------------AGGTGSIRDTTC-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6ARJ5-1", "uniprot_id": "A0A8I6ARJ5_RAT", "id": "A0A8I6ARJ5-1", "name": "Monocarboxylate transporter 11", "aln": "MRGQRAGQGLQPGSSCVRSRRQVRGREPRGAERRGERRGAATRHPHSPQFPIQGWGLCVDNSIPVGLGVRSRPGLGGLAVSRSPALGTHPHPHPVSQVARAPVVISVYRRERSKLGSISALASCSAEPCLPGKRGENSAEPTLALSLPPTPGEVGPGSRAHAPGDVPTLGEQPEAGSQGRQLPSRGPGVETSFTGVSPPQQTAMTPKPAG---------PPDGGWGWVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFERSAQ---DTAWVSALALAVQQAASPVGSALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLGLLAGSGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLGAVTLHLTPCGALLRPLALSG----------------------------------------------------------------------------------------------DPLAP-PRTPLAALG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LGLFRRPAFSVFALGTALIGGGYFVPYVHLGPHALDQGMGGYGAALVVAVAAVGDASARLVSGWLADQGWVPLPRLLVVFGSLTGLGVLAVGLVPTVGTEEGWGAPLLAAAGAYGLSAGSYAPLVFGVLPGLVGIGGVVQATG----LVMMLMSLGGLLGPPLSGFLRDKTGDFSASFLVCSSFILSGSFIYMGLPRALPSCRPASPPATPP-----PERGELLPVPQVS-----------LLS-----------------------TGGSSSIRDTTC-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8NCK7-1", "uniprot_id": "MOT11_HUMAN", "id": "Q8NCK7-1", "name": "Monocarboxylate transporter 11", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MTPQPAG---------PPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQ---DTAWISALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGALLLPLVLPG----------------------------------------------------------------------------------------------DPPAP-PRSPLAALG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQATG----LVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGSLILSGSFIYIGLPRALPSCGPASPPATPP-----PETGELLPAPQAV-----------LLS-----------------------PGGPGSTLDTTC-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CE94-1", "uniprot_id": "MOT13_MOUSE", "id": "Q8CE94-1", "name": "Monocarboxylate transporter 13", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVRRAE----------PPDGGWGWMVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAA---RVSWIASIGIAVQQFGSPIGSALSTKLGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFTPTMACLSRYFSQRRSLAMGLALTGVGISSFAFAPLFQWLINNYAWRGALLLVSALSLHLMACGALLRPLSLTE----------------------------------------------------------------------------------------------DAAVGGPGAQIT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLLRHGPFLRYTAALTLINTGFFIPYVHLVAHLQDLGWDPLPAAFLLSVAAVSDLVGRVASGWLGDAVPGPVARLLMLWTTLTGVSLALFPVAQAS-------STLVVLAVAYGFTSGALTPVAFSVLPELVGTGRIYCGMG----LVQMIESIGGLLGAPLSGYLRDVTGNYTASFVVAGAFLLAGSGVLLTLPHFFSCISVSTSRP-----------QDLVIEASDT-----------KIP-----------------------LPKEEGLGEN---------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q66HE2-1", "uniprot_id": "MOT13_RAT", "id": "Q66HE2-1", "name": "Monocarboxylate transporter 13", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVHRTE----------PPDGGWGWMVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAA---RVSWIASIGIAVQQFGSPIGSALSTKLGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFTPTLACLSRYFSQRRSLAMGLALTGVGISSFAFAPLFQWLLNNYAWRGALLLVSALSLHLVACGALLRPLSLTE----------------------------------------------------------------------------------------------DTAVGGPWAQIT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLLCHGPFLRYTVALTLINTGYFIPYVHLVAHLQDLGWDPLPAAFLLSVAAISDLVGRVASGWLGDAVPGPVARLLMLWTTLTGVSLALFPVAQAS-------TTLVVLAVAYGFTSGALTPVAFSVIPELVGTGRIYCGLG----LVQMIESVGGLLGAPLSGYLRDVTGNYTASFVVAGAFLLAGSGVLITLPHFFSCISLSTSRP-----------QDLVIEAPDT-----------KIP-----------------------LPKEEGLGEN---------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q7RTY0-1", "uniprot_id": "MOT13_HUMAN", "id": "Q7RTY0-1", "name": "Monocarboxylate transporter 13", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MARRTE----------PPDGGWGWVVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAA---RVSWIASIGIAVQQFGSPVGSALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFAPTLACLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLVACGALLRPPSLAE----------------------------------------------------------------------------------------------DPAVGGPRAQLT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLLHHGPFLRYTVALTLINTGYFIPYLHLVAHLQDLDWDPLPAAFLLSVVAISDLVGRVVSGWLGDAVPGPVTRLLMLWTTLTGVSLALFPVAQAP-------TALVALAVAYGFTSGALAPLAFSVLPELIGTRRIYCGLG----LLQMIESIGGLLGPPLSGYLRDVTGNYTASFVVAGAFLLSGSGILLTLPHFF-CFSTTTSGP-----------QDLVTEALDT-----------KVP-----------------------LPKE-GLEED---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1QL69-1", "uniprot_id": "A0A8M1QL69_DANRE", "id": "A0A8M1QL69-1", "name": "Monocarboxylate transporter 13", "aln": "---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEKPQKTEEEQRPCPQGAAPDGGWGWVVVGALFVISALVFGLIRSLGVFFVEFVQYFDESAQ---AVSWITSIGLAMQQLMSPIGAAASNVYGTRPVVMMGGFLSGLGFILASQATSLLHLYLTMGLISGLGWALVFTPTMASVMQYFTKRRSLAMGLGFTGVGLASFAFSPLFQYLVEAYAWRGALLILGGLSFNMVACGALIRPLGTPK----------------------------------------------------------------------------------------------VAVKTENSTKLNKCSFL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSRIYECFELSLLTHRGFVTYAVAITFFNAGYFIPYVHLVAHSRHIGFTEYQAAFVISITGVADIVGRVASGWASDLGKIRLLHMLVVWTGLLGLSLMLIPVAVVY-------AGLLLVSIVYGFCAGAMAPLAFAVVPEIVGIERVLGALG----LLQLIESAGGLLGAPLSGWLKDSTGTYTVSFIAAGSFLMIGMLIAMTLPYFWSCTAPPAPSPSKKKSQEGSAEDGLIGESTSSNAINETLCSGDHIPYSDEEVKVCLSNDATHSVQEQEEIPQEMTHRSNFA-------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W0L6-1", "uniprot_id": "Q9W0L6_DROME", "id": "Q9W0L6-1", "name": "", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------MVDTNSSNPGIVGGNSASSARLRRFERTDSELACEEAARLTAEQSPEDEDNQDNDEDDDDEESVYGELPPPPDGGYGWVICFASFMCNMIVDGIAYTFGIFLEEFVAYFHEGKG---TVAWVGSLLSGVYLSAGPIVSALANKYGCRAVCIAGSIIACIAFVLSTFSTNVSMLMATYGFMGGFGFGMIYLPAVVAVGYYFETKRSLATGIAVCGSGFGTFAFAPLATYLLEEYGWKNALLIFAGLILNCAIFGAMMRPLTYPKKKKQKPLMQRMYEEKQLQLERGSFAGSHFMVQLPDGTIERKLKMPLNADPGVHSSLNLELLAQQAGGGGLHPVSTLPTITESKVVDVHRQNGAQSPPNGDSNGQLSARSAAGAVGRRPHRNSESENSPYHSQDAMTRNASQPAFLAGDHQSLPKNGSVPAFNTRVRKTSASERFQPSLAAIRATSRGDLEAGAGGDFASSKLSLSQRQGGSQTGSSGRMVRPMSRKDIFYSGSVTNLPQYQSQKSLANYRNSVLSLTKYEKSMQSVAKLDPLAEAEKHREEYDLCPCLGIPDSVKSVVNTMLDVSLLKDPVFMLIGVSNIFGMAGLYVPFVYLVDAAKEHDIPKNDAAMLLSIIGITNTVGRVFCGWVADLPQVNSLLLNNCCLLVSTIAVTLTPLCYSY-------AAYITMSIFFGLAISGYISLTSIILVDLLGLDKLTNAFG----LLILFRGFAALIGTPLAGAIYDMTHTYDLPFYMAGALFGISTITSFLAPCLKRCSPSEETPVHVETLTPIDEEQGEDAEDDEDQPITIVPKIIKTLAS----------------------PQQEEGHPQFPQKTSESKL", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P36032-1", "uniprot_id": "MCH2_YEAST", "id": "P36032-1", "name": "Probable transporter MCH2", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSEERHEDHHRDVENKLNLNGKDDINGNTSISIEVPDGGYGWFILLAFILYNFSTWGANSGYAIYLAHYLENNTFAGGSKLDYASIGGLAFSCGLFFAPVITWLYHIFSIQFIIGLGILFQGAALLLAAFSVTLWEIYLTQGVLIGFGLAFIFIPSVTLIPLWFRNKRSLASGIGTAGSGLGGIVFNLGMQSILQKRGVKWALIAQCIICTSLSTIALMLTRTTHQG---------------------------------------------------------------------------------------------LRQHKRSYKFELLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDVLSNFAVWLLFGFVSFAMLGYVVLLYSLSDFTVSLGYTSKQGSYVSCMVSVGSLLGRPIVGHIADKYGSLTVGMILHLVMAILCWAMWIPCKNLA--------TAIAFGLLVGSIMGTIWPTIASIVTRIVGLQKLPGTFGSTWIFMAAFALVAPIIGLELRSTDTNGNDYYRTAIFVGFAYFGVSLCQWLLRGFIIARDEIAVREAYSAD------QNELHLNVKLS-----------HMS------------------------KCLFRYKQLPRRV-----", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ****:**.: : : . * .: : . : : .: . .*: : . : : * .: .::::: : : : *.: * * .: : *:: : :* :* ** *:. * * . : : ::. . : :*: : . :: : .:: . : * : * . .: : .: .: . .* * .* : : . * . . :: ::* : * :: : . ::* * . : . : .: : : . : :. . ", "identical_positions": 31, "similar_positions": 105, "identity": "3.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120910-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9JK42-1", "uniprot_id": "PDK2_MOUSE", "id": "Q9JK42-1", "name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial", "aln": "------------MRWV-------------RALLKNASLAGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLR--QELPVRLANIMKEINLLPDRVLGTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYGD--DPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDGSTNPAHPKHIGSIDPNCSVSDVVKDAYDMAKLLCDKYYMASPDLEIQEVNAT-NANQPIHMVYVPSHLYHMLFELFKNAMRATVESH--ESSLTLPPIKIMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTAPTPQPG--------TGGTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q64536-1", "uniprot_id": "PDK2_RAT", "id": "Q64536-1", "name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial", "aln": "------------MRWF-------------RALLKNASLAGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLR--QELPVRLANIMKEINLLPDRVLSTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYGD--DPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDGSTNPAHPKHIGSIDPNCSVSDVVKDAYDMAKLLCDKYYMASPDLEIQEVNAT-NATQPIHMVYVPSHLYHMLFELFKNAMRATVESH--ESSLTLPPIKIMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTAPTPQPG--------TGGTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q15119-1", "uniprot_id": "PDK2_HUMAN", "id": "Q15119-1", "name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial", "aln": "------------MRWV-------------WALLKNASLAGAPKYIEHFSKFSPSPLSMKQFLDFGSSNACEKTSFTFLR--QELPVRLANIMKEINLLPDRVLSTPSVQLVQSWYVQSLLDIMEFLDKDPEDHRTLSQFTDALVTIRNRHNDVVPTMAQGVLEYKDTYGD--DPVSNQNIQYFLDRFYLSRISIRMLINQHTLIFDGSTNPAHPKHIGSIDPNCNVSEVVKDAYDMAKLLCDKYYMASPDLEIQEINAA-NSKQPIHMVYVPSHLYHMLFELFKNAMRATVESH--ESSLILPPIKVMVALGEEDLSIKMSDRGGGVPLRKIERLFSYMYSTAPTPQPG--------TGGTPLAGFGYGLPISRLYAKYFQGDLQLFSMEGFGTDAVIYLKALSTDSVERLPVYNKSAWRHYQTIQEAGDWCVPSTEPKNTSTYRVS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1Q154-1", "uniprot_id": "A0A8M1Q154_DANRE", "id": "A0A8M1Q154-1", "name": "Protein-serine/threonine kinase", "aln": "------------MKFV-------------RFIMKNAALANVPHHIEHFSKFSPSPLSMKQFLDFGSTNACEKTSFVFLR--QELPVRLSNIMKEINLLPKRLLTTPSVQMVHSWYIQSLMEILEFLEKSPDDHSILEEFVAALVNIRNRHNDVVPTMAQGVIEYKEVFGQ--DPVTNQNIQYFLDRFYLSRISIRMLINQHTLVFDGATNPVHPNTIGSIDPHCQVADVVKDAYESARMLCDQYYLNSPDLDLQELNTN-NRNQPISIVYVPSHLYHILFELFKNAMRATIESH--KEGSNLPAIQVMVAVGGEDLTIKMSDRGGGVPFRKMENLFSYMYSTAPTPQMDE-------KQRAPLAGFGYGLPISRLYAKYFQGDLQLYSMEGHGTDAVIHLKALSTDSVERLPVFNKTARRNYEVTQGADDWCVPSREPLDLAVFKLAK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P91622-1", "uniprot_id": "PDK_DROME", "id": "P91622-1", "name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase, mitochondrial", "aln": "------------MRLFP-----------VRFSAASSSMASLAKMLDFYSGFNPSPLSIKQFMDFG-QNACEKKSYIFLR--KELPVRLANIMKEIALLPDNLLHTRSVSEVSSWYVKSFEDVLVYEKAEP-THDNLQKFVADLDLIRNRHNDVVQTMAQGVIEMKENEGGQVDAPTESSIQYFLDRLYMSRISIRMLINQHTLLFGGNPHAGG-RHIGCLDPACDLSDVVRDAYENARFLCDQYYLTSPALEIQQHSSEPGDNLPIRTVYVPSHLYYMLFELFKNSMRAVVEHHGHDNNDTLPPLKVAICKGKEDICVKISDQGGGIPRSQTDQLFKYMYSTAPQPSKSD-------LHTVPLAGYGYGLPISRLYARYFHGDIVLLSCEGFGTDAIIYLKALSDEANELLPIFNKTSSKFYRATVPTGDWSNQVKYAKKKKTSAVNQ", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P40530-1", "uniprot_id": "PDK1_YEAST", "id": "P40530-1", "name": "[Pyruvate dehydrogenase (acetyl-transferring)] kinase 1, mitochondrial", "aln": "MWKIMRSWKCGGMRWAHRQRPSHELLSQLSFDQHYKIRSNIELLIQDYASKPIAPLNYEYFLQYRPPLTKKEEYMLTIKTINLLLSLTCKRLNAIQRLPYNAVINPHIERTNSLYLKSLQTLLSIA--YPYELHNPPKIQAKFTELLDDHEDAIVVLAKGLQEIQSCYPK-------FQISQFLNFHLKERITMKLLVTHYLSLMAQNKGDTNKRMIGILHRDLPIAQLIKHVSDYVNDICFVKFNTQRTPVLIHPPSQ-----DITFTCIPPILEYIMTEVFKNAFEAQIALG----KEHMPIEINLLKPDDDELYLRIRDHGGGITPEVEALMFNYSYSTHTQQSADSESTDLPGEQINNVSGMGFGLPMCKTYLELFGGKIDVQSLLGWGTDVYIKLKGPSKTALLSKK------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *: :. :: :: :**. : *::: : :: :: : * .: :: * ** . : . :. . * *::*: :: * :: : : : *:*.: .:*:*: * :. .*. **: .**::::*:.:: :: . ** :. ::::::.. : .. :* : . : . : * . :*. * ::: *:***::.* : :* : . ::: ::: *:***:. :*.* *** . . . ::* *:***:.: * . * *.: : * * ***. * **. * : ", "identical_positions": 61, "similar_positions": 123, "identity": "13.62%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120910-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O35305-1", "uniprot_id": "TNR11_MOUSE", "id": "O35305-1", "name": "Tumor necrosis factor receptor superfamily member 11A", "aln": "MAPRARRRRQLPAPLLALCVLLVPLQVTLQVTPPCTQERHYEHLGRCCSRCEPGKYLSSKCTPTSDSVCLPCGPDEYLDTWNEEDKCLLHKVCDAGKALVAVDPGNHTAPRRCACTAGYHWN-SDCECCRRNTECAPGFGAQHPLQLNKDTVCTPCLLGFFSDVFSSTDKCKPWTNCTLLGKLEAHQGTTESDVVCSSSMTLRRPPKEAQAYLPSLIVLLLFISVVVVAAIIFGVYYRKGGKALTANLWNWVNDACSSLSGNKESSGDRCAGSHSATSSQQEVCEGILLMTREEKMVPE-----DGAGVCGPVCAAGGPWAEVRDSRTFTLVSEVETQGDLSRKIPTEDEYTDRPSQPSTGSLLLIQQGSKSIPPFQEPLEVGENDSLSQCFTGTESTVDSEGCDFTEPPSRTDSMPVSPEKHLTKEIEGDSCLPWVVSS--NSTDGYTGSGNTP---GEDHEPFPGSLKCGPLPQCAYSMGFPSEAAASMAEAGVRPQDRAD------ERGASGSGSSPSDQPPASGNVTGNSNSTFISSGQVMNFKGDIIVVYVSQTSQEGPGSAEPESEPVGRPVQEETLAHRDSFAGTAPRFPDVCATGAGLQEQGAPRQKDGTSRPVQEQGGAQTSLHTQGSGQCAE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9Y6Q6-1", "uniprot_id": "TNR11_HUMAN", "id": "Q9Y6Q6-1", "name": "Tumor necrosis factor receptor superfamily member 11A", "aln": "MAPRARRRRPLFA-LLLLCALLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHWS-QDCECCRRNTECAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGKRVEHHGTEKSDAVCSSSLPARKPPNEPHVYLPGLIILLLFASVALVAAIIFGVCYRKKGKALTANLWHWINEACGRLSGDKESSGDSCVSTHTANFGQQGACEGVLLLTLEEKTFPEDMCYPDQGGVCQGTCVGGGPYAQGEDARMLSLVSKTEIEEDSFRQMPTEDEYMDRPSQPTDQLLFLTEPGSKSTPPFSEPLEVGENDSLSQCFTGTQSTVGSESCNCTEPLCRTDWTPMSSENYLQKEVDSGHCPHWAASPSPNWADVCTGCRNPP---GEDCEPLVGSPKRGPLPQCAYGMGLPPEEEASRTEARDQPEDGADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFISSGQVMNFKGDIIVVYVSQTSQEG---AAAAAEPMGRPVQEETLARRDSFAGNGPRFPDPCGGPEGLREP------EKASRPVQEQGGAKA------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F027-1", "uniprot_id": "E7F027_DANRE", "id": "E7F027-1", "name": "", "aln": "-MRVIFSASWIFQGWITYFVLALCTQTGQAIS---CQQNEYVYNGRCCEKCKAGTHVLEHCNGRSKTRCFDCGFDQYQPDWNNKMYCISQKYCDEGKGFNRTRPQNPTAPEPCRCKQGFHCSLINCEYCEAIEECPP--GKGVVMGVNGRASCVSCPAGTFSDSLS-KESCKKWTDCKAIGKTEKQLGSTTTDAVCG---------LHSSGMTPWVVVAILSVIIVVSLVVLCLFCCKDKLNFLSVNLRTCVQNLKGTRN-QQETLTNSYHCSHSPQT---------LPLICQELTPPE--------------------FLINCPSTHITISDELLPYTNQDQDQDCAETSSGGSSEDSGCGPSSPLSGSSCSCAPKEPVEVGENEDCSQLVATGLATCCS--CRTGDETAEHEQVIILKEPLLCDGLPACDYVHLHRSQELYLDFSSPAGKDAMSEMRDDRGLVEGSYRQNEPRCCSIDSTTIPSLLSVSDNDQGLSLIHSDEHKLSELDTDEDYQNQCSDSALTSGQVTGNNNTTFISSGQVMNFSGEVIVVYVSQTSLGS---SGGTDEPFSCPVQEE--SNEDSLQ-NQPKSNSSTAPPAKTRNAR-----LEKQLPVQEMTSDLSWQK---------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : .* *. :: .:..* : ****.:*:.*.:: .:*. *.: *: ** *:* **:: *: :* ** **.: . . * *:*. * *. *:* . :** *. **.* * : :* : * .* * *** :* .:.*: **:*. :** : *: :*.**. .. * ::: :* :.: .:: . :. : *:.** ::: . . ::*: : :*:. * : :* ** : : ::: .: : :. : . .*: : **.. . .**:*****:. ** .: :* * * : .. : : * * . : . * .. :. :* . ** : . *: . .. : : . :* . .. .... :**:****.*:***********.*::********* . : **.. ***** :..**: . *: . . :: . **** . : ", "identical_positions": 132, "similar_positions": 170, "identity": "20.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120912-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L4V2-1", "uniprot_id": "A0ABK0L4V2_RAT", "id": "A0ABK0L4V2-1", "name": "Transmembrane protein 138", "aln": "GVPEQILVRVLGALRPVSLVSNHRPPSRNRRNAGVNSLSLGLALSEAGWKNRSQGESGKAKALTWRAISNLLPEFKVGFRKPVWCSHDNRHRFFEVSVDDADRRVAGSQNFVLLLLLLWVFFPFRCVNGLVRFLLLCYDLFVNSFS-ELLRMAPVIQLVLFIIQDIAILFNIIIIFLMFFNTFVFQAGLVNLLFHKFKGTIILTSVYLALSISLHVWVMNVRWK--DSSSFRWTNGLQTLFVFQRLAAVLYCYFYKRTAVRLGDPRFYQDSL-WLRKEFMQVRR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D6G5-1", "uniprot_id": "TM138_MOUSE", "id": "Q9D6G5-1", "name": "Transmembrane protein 138", "aln": "--------------------------------------------------------------------------------------------------------MLQTGNYSLVLSL--------------QFLLLSYDLFVNSFS-ELLRMAPVIQLVLFIIQDIAILFNIIIIFLMFFNTFVFQAGLVNLLFHKFKGTIILTSVYLALSISLHVWVMNVRWK--NSSSFSWTNGLQTLFVFQRLAAVLYCYFYKRTAVRLGDPRFYQDSL-WLRKEFMQVRR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9NPI0-1", "uniprot_id": "TM138_HUMAN", "id": "Q9NPI0-1", "name": "Transmembrane protein 138", "aln": "--------------------------------------------------------------------------------------------------------MLQTSNYSLVLSL--------------QFLLLSYDLFVNSFS-ELLQKTPVIQLVLFIIQDIAVLFNIIIIFLMFFNTFVFQAGLVNLLFHKFKGTIILTAVYFALSISLHVWVMNLRWK--NSNSFIWTDGLQMLFVFQRLAAVLYCYFYKRTAVRLGDPHFYQDSL-WLRKEFMQVRR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FDE0-1", "uniprot_id": "TM138_DANRE", "id": "E7FDE0-1", "name": "Transmembrane protein 138", "aln": "--------------------------------------------------------------------------------------------------------MLQTNNYSLVLLI--------------QLALLTFDLFVNSFS-ELLRSAPVIQLVLFIIQDIGILFNVIIILLMMFNTYVFQVGLVSLLLERFRAMLILSALYLTLSICFHCWVMNLRWM--ESNRFVWTDGLQVLFVFQRIAAVLYYYFYKRTTEYLGDPRLYEDSP-WLRDAFARARQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VMK8-1", "uniprot_id": "Q9VMK8_DROME", "id": "Q9VMK8-1", "name": "Transmembrane protein 138", "aln": "-------------------------------------------------------------------------------------------------------MKLTLRRYSWVLLF--------------QFALLGVDLFCNAFGPSLARNRLQTAIILFVTQDALIIAEYLLFTLALHSTCVYQVGASHIILRNCKLFMASITIYFLLSASQHFWIIYQYRQPPEEDGHHWPLGLIALSVAQRIMSVFYYYSSKSTALTMADPRFKEEHLDWIADQLGDK--", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: :* : :: ** *** *:*. .* : ::**: ** :: : ::: * :..* *:*.* :::.. : : ::*: ** . * *:: :.. . *. ** * * **: :*:* * * *: :.**:: :: *: . : ", "identical_positions": 38, "similar_positions": 55, "identity": "13.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120913-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q66HR9-1", "uniprot_id": "SAXO4_RAT", "id": "Q66HR9-1", "name": "Stabilizer of axonemal microtubules 4", "aln": "MMGKLPLGVVSPYVKMSSGG---CSDPLKFYATSYCTAYGREEFKPRMGSHVGTGYKSNYRPLVSYQPHLDTLDNPAVGEQIHDTSKSVASQSYAPLEVPDGKQPLPWN-LHQTTSGYGREKVNIGPLSKEVRKVHFDTQDHGPQTITGLEPKEVPLIHQQQGKGSTEWENSRYGPRFMTSEYNSKYLKESPNHPDLLLKKTIGSKEETGFTEESTKNPIVFQPPSQAYPGDPVLHPGRSITKSDYLPISHPQGNEFLPVLARGSDRDTGYSRVSERSLNPRMPTPSSQPTSMSHRSYQPPQRMQQSNVALLGRESVGNKEPTGFTLNNPSYVRSSYEQDRDQRYLTTYNQGYFENIPKGLDREGWTRGGIQPQKAGAYALSEPVTH--MDTTPNPTETLRHLHPHVGRTLTSVDPFYRDVPHSNRYPTSS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q148A4-1", "uniprot_id": "SAXO4_MOUSE", "id": "Q148A4-1", "name": "Stabilizer of axonemal microtubules 4", "aln": "MMGKLPLGVVSPYVKMSSGG---CSDPLKFYATSYCTAYGREEFKPRLGSHVGTGYKSNYRPLVSYQPHLDTLDNPAIGQQIRDTSKSVTSQSYSPLEVPDGKQPLPWN-LHQTTSSYGREKLNPGPHSKEVRKVHFDTQDHGPQTITGLEPKEVPLIHQQQGKGSTEWENSHYGPRFMTSEYNSKYIKESPNHPDLLLKKTIGSKEETGFTEESTKNPIVFQPPSQAFPGDPVLHPGRSITKSDYLPVTHPQGSDFLPVLSRGSDRDTGFSRVNERTLNPRVPTPAPQPASMSHRSYQPPQRMQQTNVALLGRESVGNKEPTGFTLNNPSYVRSSYEQDRDQRYLTTYNQGYFENIPKGLDREGWTRGGIQPQKAGAYALSELNNHTLMDSTPNPTETLRHLHPHVGRTLASVDPFYRDMPHSSRYPASS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q7Z5V6-1", "uniprot_id": "SAXO4_HUMAN", "id": "Q7Z5V6-1", "name": "Stabilizer of axonemal microtubules 4", "aln": "MMGKLPLGVVSPYVKMSSGG---YTDPLKFYATSYCTAYGREDFKPRVGSHVGTGYKSNFQPVVSCQASLEALDNPARGEQAQDHFQSVASQSYRPLEVPDGKHPLPWS-MRQTSSGYGREKPSAGPPTKEVRKVHFDTQEHGPQAITGLEPREVPLLHQQQGQDPLERENFRHGPRFMTSEYNSKYLRDPLDQPDFLQKKSIGAKEGSGFTKQSHQSPIVFQPPSQALPGDPALLPGQSVTKSDFLPKTHLHGDEFLPVLARGSKRETAFSRGNERILNPRVPPPCPEPSSVSHQQFQPLHRMQQTNVALLGRETVGKKEPTGFSLNNPMYVRSPCDPDRDQRYLTTYNQGYFENIPKGLDQEGWTRGGIQPQMPGGYALSQPVSC--MEATPNPMESLRHLHPHVGRTLTSADPFYQNTPHSSRCVAHS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7TC15-1", "uniprot_id": "A0A8N7TC15_DANRE", "id": "A0A8N7TC15-1", "name": "", "aln": "MVG--PLGVIKPSFGTGRPAGRPANISIDHYCTSYRQSYGKELFQPCLGYHHGTGYSANHRPVLYYSSRLDDYDNPQFGFSLLDSFESQSKRHYQRLVQPDGTEPLACSGSRRRESGY-------------------------------LQLQSQPRLRTASCQTEYKGAYIPHSPRVVGASDD---------------RVLIGPIQDSGYTEGANLQLHTFLP--KYVNMDDARRTQESVMRTDFLAGSFLQGREAFPKLASHSNRETGFTRDTNR--------PLTSSTSLQHGISQDNRQKTRPNVATLSIGPVGS---SGFVLNAPNITRLSQTPADPQHFLTHYQSKFYNKSLTEQQRSDWMRGGIQKHRKSGYSGRDTDRFN--------------LSGY-------------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:* ****:.* . . . . .:..*.*** :**:* *:* :* * ****.:*.:*:: .. *: *** * . * :* :.: * * ***..**. . :: *.* *: :. * :: . : : :.**.: :. : : **. : :*:*: : . .* * : * . . .*: ::*:*. :. :* : :* *: *.*:*.::* .:* * ...:*:.* * :: :.*** *. .**. :** ** * .* . *::** *:. :::: . ::..* ***** : ..*: : * : ", "identical_positions": 90, "similar_positions": 118, "identity": "20.88%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120913-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99JG7-1", "uniprot_id": "TNIP2_MOUSE", "id": "Q99JG7-1", "name": "TNFAIP3-interacting protein 2", "aln": "MSSGDPRSGRQDGAPRAAAALCGLYHEAGQQLQRLKDQLAARDALIASLRTRLAALEG------------HTAPSLVDALLDQVERFREQLRRQEEGASETQLR--QEVERLTERLEEKEREMQQLMSQPQHEQEKEVVLLRRSVAEKEKARAASDVLCRSLADETHQLRRTLAATAHMCQHLAKCLDERQCAQGDAGEKSPAELEQTSSDASGQ-SVIKKLQEENRLLKQKVTHVEDLNAKWQRYDASRDEYVKGLHAQLK-------------RRQVPLEPELMKKEISRLNRQLEEKISDCAEANQELTAMRMSRDTALERVQMLEQQILAYKDDFKSERADRERAHSRIQELEEKIMSLMYQVSQRQDSREPGPCRIHTGNKTAKYLEMDALEHVTPGGWRPESRSQQMEPSAEGGHVCTAQRGQGDLQCPHCLRCFSDEQGEAFLRHLSECCQ-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8NFZ5-1", "uniprot_id": "TNIP2_HUMAN", "id": "Q8NFZ5-1", "name": "TNFAIP3-interacting protein 2", "aln": "MSR-DPGSGGWEEAPRAAAALCTLYHEAGQRLRRLQDQLAARDALIARLRARLAALEG------------DAAPSLVDALLEQVARFREQLRRQEGGAAEAQMR--QEIERLTERLEEKEREMQQLLSQPQHEREKEVVLLRRSMAEGERARAASDVLCRSLANETHQLRRTLTATAHMCQHLAKCLDERQHAQRNVGERSPDQSEHTDGHTSVQ-SVIEKLQEENRLLKQKVTHVEDLNAKWQRYNASRDEYVRGLHAQLR-------------GLQIPHEPELMRKEISRLNRQLEEKINDCAEVKQELAASRTARDAALERVQMLEQQILAYKDDFMSERADRERAQSRIQELEEKVASLLHQVSWRQDSREPDAGRIHAGSKTAKYLAADALELMVPGGWRPGTGSQQPEPPAEGGHPGAAQRGQGDLQCPHCLQCFSDEQGEELLRHVAECCQ-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AA70QPX0-1", "uniprot_id": "A0AA70QPX0_DANRE", "id": "A0AA70QPX0-1", "name": "TNFAIP3-interacting protein 2", "aln": "MDEMKRENEALRAKLRSCSTLNTIYHETQQEIARLNQLVTSKDGIIADLRARLGKYEKTVVIEGEEPYIVGPSKSLIESLCKEICKLKQKLKDLEKDTAQKLETRDKEIQRLQEKLKERDQELLTIRERPEQEKEREIQQLRTTLAERDRTQATRTVLCNSLAEEADQLRAQLGATVQVCQELLGRLENEKNKTAMTDQRTQVHETSDSPEVPQLNVIISKLEEENDQLKKRVAYVESLNSKWQKYDSSREEYVRGLCQKLKESNGLASADPTLTQAPTAGHVALFQQEIVRLNGLLQDKMMECERFSRERDDNARR---DQEQIQMLEQQVLAYVEDFKSERADRERAQGKIMDLQDEVGRLQLQIRSQN-------VQEASTSRHKKIMALKKASHRQTETAEP-LRNSPPETSSKRTISNTAPQGAAELQCPRCFIRFDDEHTTEYLKHWDECAKL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . . *:.::* :***: *.: **:: ::::*.:** **:**. * .: **:::* .:: :::::*: * .::: :*::** *:*:*:::*: : .:*::*:*:*: ** ::** ::::*: ***.***:*:.*** * **.::**.* *::.: ..::: . . ... :*.**:*** **::*::**.**:***:*::**:***:** :*: . . *:::** *** *::*: :* . .:* *::******:*** :** *********:.:* :*:::: * *: :: : : .: * : . . . .* .. *..:: :* :* .:****:*: *.**: *:* **.: ", "identical_positions": 132, "similar_positions": 154, "identity": "28.76%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120913-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96AD5-1", "uniprot_id": "PLPL2_HUMAN", "id": "Q96AD5-1", "name": "Patatin-like phospholipase domain-containing protein 2", "aln": "MFPREKTWNISFAGCGFLGVYYVGVASCLREHAPFLVANATHIYGASAGALTATALVTGVCLGEAGAKFIEVSKEARKRFLGPLHPSFNLVKIIRSFLLKVLPADSHEHASGRLGISLTRVSDGENVIISHFNSKDELIQANVCSGFIPVYCGLIPPSLQGVRYVDGGISDNLPLYELKNTITVSPFSGESDICPQD-SSTNIHELRVTNTSIQFNLRNLYRLSKALFPPEPLVLREMCKQGYRDGLRFLQRNGLLNRPNPLLALPPARP---HGPEDKDQAVESAQAEDYSQLP--GEDHILEHLPARLNEALLEACVEPTDLLTTLSNMLPVRLATAMMVPYTLPLESALSFTIRLLEWLPDVPEDIRWMKEQTGSICQYLVMRAKRKLGRHLPSRLPEQVELRRVQSLPSVPLSCAAYREALPGWMRNN-LSLGDALAKWEECQRQLLLGLFCTNVAFPPEALRMRAPADPAPAPADPASPQHQLAGPAPLLSTPAPEARPVIGALGL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8BJ56-1", "uniprot_id": "PLPL2_MOUSE", "id": "Q8BJ56-1", "name": "Patatin-like phospholipase domain-containing protein 2", "aln": "MFPRETKWNISFAGCGFLGVYHIGVASCLREHAPFLVANATHIYGASAGALTATALVTGACLGEAGANIIEVSKEARKRFLGPLHPSFNLVKTIRGCLLKTLPADCHERANGRLGISLTRVSDGENVIISHFSSKDELIQANVCSTFIPVYCGLIPPTLQGVRYVDGGISDNLPLYELKNTITVSPFSGESDICPQD-SSTNIHELRVTNTSIQFNLRNLYRLSKALFPPEPMVLREMCKQGYRDGLRFLRRNGLLNQPNPLLALPPVVP---QEEDAEEAAVVEERAGEEDQLQPYRKDRILEHLPARLNEALLEACVEPKDLMTTLSNMLPVRLATAMMVPYTLPLESAVSFTIRLLEWLPDVPEDIRWMKEQTGSICQYLVMRAKRKLGDHLPSRLSEQVELRRAQSLPSVPLSCATYSEALPNWVRNN-LSLGDALAKWEECQRQLLLGLFCTNVAFPPDALRMRAPAS--PTAADPATPQDPPGLPPC------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B5X2-1", "uniprot_id": "A0ACD6B5X2_DANRE", "id": "A0ACD6B5X2-1", "name": "triacylglycerol lipase", "aln": "MFPLDSPWNISFAGCGFLGIYHIGVASCLQEHAPFLVENARHIYGASAGALTASALVTGACLGEAGANIIDVAKEARKRFLGPMHPSFNLVKIMRTHLHRVMPVDGYIRATGRLGISLTRVTDGENVLVSHFNSNEELVQACICSAYIPVYCGLIPPTLQGVRYVDGGISDNLPQYELKNTITVSPFSGESDICPRDVSSTNIHELRFTNTSIQFTLANLYRVSRALFPPDPLVMKSMCKQGYRDALLFLKKNGLLQYRGPHRALAAAAEGADEESDGEDEERRDEGEPEADDHRSSMEEHVFEHLPPRVHKALVEACRERRSLLQSLSNMLPVRMASAILLPYTLPLESALSVSIRLLEWLPDIQEDVGWMKEQTLKLLNSVFSHAGRSASQQVSARVSCQLDVRRCESAP---LSSSAS-RLLPVWLSSSSSSMLDVMLRLQQYPRQLLPAMFCLNLDLR-SSLTSGHQQDMEGLIMKPLEDRDTSLTP--------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*** :. ************:*::******:******* ** ************:*****.*******::*:*:**********:******** :* * :.:*.* : :*.**********:*****::***.*::**:** :** :**********:**************** ********************:* *********.*******.* ****:*:*****:*:*::.********.* **::****: .* **... . : :: . : .: :::::****.*:::**:*** * .*: :********:*:*:::*********:*.:*********: **: ****** .: : :. :* *. . ::.:*:. *:::** :* * **.:: . ** *: .. *: *.: : :: **** .:** *: : .:* . .* :. * ", "identical_positions": 273, "similar_positions": 121, "identity": "53.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120913-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q60591-3", "uniprot_id": "NFAC2_MOUSE", "id": "Q60591-3", "name": "Nuclear factor of activated T-cells, cytoplasmic 2", "aln": "MDVPEPQPDPDGGDGPGHEPGGSPQDELDFSILFDYDYLNPIEEEPIAHKAISSPSGLAYPDDVLDYGLKPCNPLASLSGEPPGRFGEPDSIGFQNFLSPVKPAGASGPSPRIEITPSHELMQAGGALRGRDAGLSPEQPALALAGVAASPRFTLPVPGYEGYREPLCLSPASSGSSASFISDTFSPYTSPCVSPNNAGPD-DLCPQFQNIPAHYSPRTSPIMSPR-TSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVAPLPAASPQRSRSPSPQPSPHVALQDDSIPAGYPPTAGSAVLMDALNTLATDSPCGIPSKIWKTSPDPTPVSTAPSKAGLARHIYPTVEFLGPCEQEERRNSAPESILLVPPTWPKQLVPAIPICSIPVTASLPPLEWPLSNQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHVPEPSGRIVSLQAASNPIECSQRSAHELPMVERQDMDSCLVYGGQQMILTGQNFTAESKVVFMEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRVPVKVNFYVINGKRKRSQPQHFTYH--PVPAIKTEPSDEYEPSLICSPAHGGLGSQPYYPQHPMLAESPSCLVATMAPCQQFRSGLSSPDARYQQQSPAAALYQRSKSLSPGLLGYQQPSLLAAPLGLADAHRSVLVHAGSQGQGQGSTLPHTSSASQQASPVIHYSPTNQQLRGGG-------HQEFQHIMYCENF---GPSSARPGPPPINQGQRLSPGAYPTVIQQQ----------TAPSQRAAKNGP--SDQKEALPTGVTVKQEQNLDQTYLDDVNEIIRKEFSGPPSRNQT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13469-1", "uniprot_id": "NFAC2_HUMAN", "id": "Q13469-1", "name": "Nuclear factor of activated T-cells, cytoplasmic 2", "aln": "MNAPERQPQPDGGDAPGHEPGGSPQDELDFSILFDYEYLNPNEEEPNAHKVASPPSGPAYPDDVLDYGLKPYSPLASLSGEPPGRFGEPDRVGPQKFLSAAKPAGASGLSPRIEITPSHELIQAVGPLRMRDAGLLVEQP--PLAGVAASPRFTLPVPGFEGYREPLCLSPASSGSSASFISDTFSPYTSPCVSPNNGGPD-DLCPQFQNIPAHYSPRTSPIMSPR-TSLAEDSCLGRHSPVPRPASRSSSPGAKRRHSCAEALVALPPGASPQRSRSPSPQPSSHVAPQDHGSPAGYPPVAGSAVIMDALNSLATDSPCGIPPKMWKTSPDPSPVSAAPSKAGLPRHIYPAVEFLGPCEQGERRNSAPESILLVPPTWPKPLVPAIPICSIPVTASLPPLEWPLSSQSGSYELRIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLHGYMENKPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVGNTKVLEIPLEPKNNMRATIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPESSGRIVSLQTASNPIECSQRSAHELPMVERQDTDSCLVYGGQQMILTGQNFTSESKVVFTEKTTDGQQIWEMEATVDKDKSQPNMLFVEIPEYRNKHIRTPVKVNFYVINGKRKRSQPQHFTYH--PVPAIKTEPTDEYDPTLICSPTHGGLGSQPYYPQHPMVAESPSCLVATMAPCQQFRTGLSSPDARYQQQNPAAVLYQRSKSLSPSLLGYQQPALMAAPLSLADAHRSVLVHAGSQGQS--SALLHPSPTNQQASPVIHYSPTNQQLRCGS-------HQEFQHIMYCENF---APGTTRPGPPPVSQGQRLSPGSYPTVIQQQ----------NATSQRAAKNGPPVSDQKEVLPAGVTIKQEQNLDQTYLDDVNEIIRKEFSGPPARNQT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F9Z5-1", "uniprot_id": "E7F9Z5_DANRE", "id": "E7F9Z5-1", "name": "", "aln": "MSSFYGEKAALGLAAELSQVN--CQDELEFDYLFEYENQTGLQDEQGISSHSSPPSLSYPPEGVAPYAIKPCA--SSYVDVHTEGFSAYEQLEAKGYLEHARPN-NQALSPRIEITPSRELYNHGQNQ---------------LINTSPSPGLTVPGQDPLAYREPQCLSPASSNSSTSWHSENLSPWASPCVSPSNSQLSGDLCPRLQGVHTG-SPRTSPGTSPQTTSLSEDACIGPRSPSPRPGSRSTSPLCKRTY----EMYTNPNLVPVARSRSPSPHGGHKEHHVNHYISN------------NGVNGFSVGQAASVPTKIVKTNQQGYPLYSDNHTEG----------YLLSCEQDMKGKPGPEPFFVIPQIWPKQLVPG--MCSIPVSS-LPSLEWPLPSRTDQLELHIEVQPKPHHRAHYETEGSRGAVKAPTGGHPVVQLRGYRGKEPLGLQIFIGTADERILKPHAFYQVHRITGKTVTTTSYEKIVNGTKVLEIPLEPKNNMKAIIDCAGILKLRNADIELRKGETDIGRKNTRVRLVFRVHIPQQSGQYLSLQIASHPIECSQRSAHELPMVEKQDMDACSVLGGQQMILTGQNFSADSKVIFMEKTHDGQQIWELEATVDKDKSQASMLFIEVPPYRDPSICHAVKVNFYVINGKRKRSQPQHFTYTPLPVPSIKTEPVDEYESGRMGYSLSQMLGVSPQSYYSPRGVIPPDSLVPGLVPCQQTRLGVSPPDHRFQQQSPAIMYSRTGKSSSSSPIYSQTAATMIP-----DSHRSVLVHTGSPAQS--SHLGSQHPTNQHPS-IIQFSPTNHHLLRGGGDPPAPPPPEHQHIIYCEGYNQHGPQPTGANRSPAPAQAAQHPQNYPTVIQQQPFLQRVAKDRSPSAQVEPQRSSSAEEPRANVPGRVTVKQE-NLDQAYLDDVNEIIRKDLTGVHGRSQT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. : . * . : . ****:*. **:*: . ::* . *.** *:.* *.:** :* . . *. : : : :*. .:* .. *********:** : * ..:.** :*:* . .**** *******.**:*: *:.:**::******.*. . ****::*.: : ****** **: ***:**:*:* :** ***.***:** .** : : : .. *******: . : :. . :.:* ::......:*.*: **. : *: : . * :* .*** : :..**.::::* *** ***. :*****:: **.*****..::.. **:**********************************:** ::*****************************************..**************:* *************************************:*: **: :*** **:****************:** *:* * ************:::***:* *** *******:**********..***:*:* **: * .********************** ***:***** ***:. : . ** .* * . .*..**. :.**** * *:*.** *:***.** : .** *.. : * .: : . *:*******:** .*. * * .:.*:.* :*::****::* *. *.***:***.: .* .: .. .* * ******** ...:* .:... .: : :* **:*** ****:***********:::* .*.**", "identical_positions": 463, "similar_positions": 214, "identity": "48.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120914-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZNK9-1", "uniprot_id": "D3ZNK9_RAT", "id": "D3ZNK9-1", "name": "Dual specificity protein phosphatase 8", "aln": "MAGDRLPRKVMDAKKLASLLRGGPGGPLVIDSRSFVEYNSCHVLSSVNICCSKLVKRRLQQGKVTIAELIQPAARSQVDATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVAILTGGFATFSSCFPGLCEGKPATLPSMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRIPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSLKLLAALQSD-GPHLGTPEPLMGPAAGIPLPRLPPSTSESAATGSEAATAAKEGSPSAGGDALIPSTAPATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSAYAPSRRPDFPGPPDPGEAPKLCKLDSPSGGTLGLPSPSPDSPDSVPECRPRPRRR-RPPVSSPARSPAHGLALNFG-DTARQTPRHGLSALSAPGLPGPGQPSGPGGWVPPLDSPGTPSPDGPWCFSPEGAQGPG-AVFSAFGRASAGAPGPG-SGSSGGGGG--------------------------SSSSSSSSSSGDLRRRDVRTSWPE-EPAADAQFKRRSCQMEFEEGMVEGRARGEELAALGKQTSFSGSVEVIEVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O09112-1", "uniprot_id": "DUS8_MOUSE", "id": "O09112-1", "name": "Dual specificity protein phosphatase 8", "aln": "MAGDRLPRKVMDAKKLASLLRGGPGGPLVIDSRSFVEYNSCHVLSSVNICCSKLVKRRLQQGKVTIAELIQPATRSQVDATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVAILTGGFATFSSCFPGLCEGKPATLPSMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRIPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSLKLLAALQTD-GPHLGTPEPLMGPAAGIPLPRLPPSTSESAATGSEAATAAREGSPSAGGDAPIPSTAPATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSAYAPSRRPDFPGPPDPGEAPKLCKLDSPSGGTLGLPSPSPDSPDSVPECRPRPRRR-RPPASSPARSPAHGLGLNFG-DTARQTPRHGLSALSAPGLPGPGQPAGPGGWVPPLDSPGTPSPDGPWCFSPEGAQGPG-AVFSAFGRVSAGAPGPGNSSSSGGGGGGGGGGGGGGGGGGSSSSNSSSSSSSSSSSSSSSSSSSDLRRRDVRTGWPE-EPAADAQFKRRSCQMEFEEGMVEGRARGEELAALGKQTSFSGSVEVIEVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q13202-1", "uniprot_id": "DUS8_HUMAN", "id": "Q13202-1", "name": "Dual specificity protein phosphatase 8", "aln": "MAGDRLPRKVMDAKKLASLLRGGPGGPLVIDSRSFVEYNSWHVLSSVNICCSKLVKRRLQQGKVTIAELIQPAARSQVEATEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVAILTGGFATFSSCFPGLCEGKPAALLPMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMRVPINDNYCEKLLPWLDKSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMKTMGMSSDDAYRFVKDRRPSISPNFNFLGQLLEYERSLKLLAALQGDPGTPSGTPEPPPSPAAGAPLPRLPPPTSESAATG---NAAAREGGLSAGGEPPAPPTPPATSALQQGLRGLHLSSDRLQDTNRLKRSFSLDIKSAYAPSRRPDGPGPPDPGEAPKLCKLDSPSGAALGLSSPSPDSPDAAPEARPRPRRRPRPPAGSPARSPAHSLGLNFG-DAARQTPRHGLSALSAPGLPGPGQPAGPGAWAPPLDSPGTPSPDGPWCFSPEGAQGAGGVLFAPFGR--AGAPGPG-----GG-------------------------------SDLRRREAARAEPRDARTGWPE-EPAPETQFKRRSCQMEFEEGMVEGRARGEELAALGKQASFSGSVEVIEVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RKU2-1", "uniprot_id": "A0A8M1RKU2_DANRE", "id": "A0A8M1RKU2-1", "name": "", "aln": "----------MHESEMRLKMR----------------------------------VRRIKEG-------------------------------RD--------------------------LRGGFAAFSSCFPELCENKPASILPLSLSQPCLPVANIGPTRILPHLYLGSQRDVLNKEVMSQNGITYVLNASNTCPKPDFISENHFMRIPVNDSYCEKLLPWLEKTNEFIDKAKVSNCRVIVHCLAGISRSATIAIAYIMKTMGLSSDDAYRFVKDRRPSISPNFNFLGQLLEFERGLEMKKSLPCP--------------------IRMEASTVKEVTEIRKMENDDQRTSQTT----EITVNPPSPTSLQKDLSSLHLSTEKILQNKRLKCSFSLDIKSVYSSSPNHNSSPNSDSENTPKICRIDNLKN-TNGVGQS---------QCMIATQIG-------FKRLSATSLSLNLKQENSGLQDQNCENNKKASLLLGKSASWTTHRGSNQASTPITPTGDCPWFLAANLAPSGTSAHFGSTSTYSAYSCSGQSGNPKPGAYQ--------------------------RDKTQGDSREISSWLDDGKTQIVCGISQVDTKYKRRSCQMEFEDGMSTTQS-GEDFGNLGKQSSFSGSMEVIEVS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *. .:: :* **:::* ** * ****:****** ***.***:: .:*********..:* ************:*****::*:****:*******:*******.*.:***:*:**.*********:*: *******:*.*:*************************:****************************:**.*:: :* *: ..* :..: :. . :: . ..*:.::**:.* .****:::: :.:*** ********.*:.* . : . .*. ::**:*::*. .. : *: .. :. .: * .* .*.**: : : :: . .*. * * . . . .:* **: * ** ::.: * . . *.. . * : . * . * :* . ::::**********:** :: **::. ****:*****:******", "identical_positions": 231, "similar_positions": 136, "identity": "34.58%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120917-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6AY40-1", "uniprot_id": "JMJD8_RAT", "id": "Q6AY40-1", "name": "JmjC domain-containing protein 8", "aln": "MAAAGRFGLLLLIVLWTMVTVVLPAS---GEGGWKQSRLGTEAAVMEEERCTVERR--AHLTYSEFMQHYAFLKPVILQGLTDNSKFRALCSRENLLASFGDNVVRLSTANTYSYQKVDLPFQEYVEQLLHPQDPESLGNDTLYFFGDNNFTEWAPLFQHYRPPPFRLLGTTPAYSFGIAGAGSGVPFHWHGPGFSEVIYGRKRWFLYPPEKTPEFHPNKTTLAWLLEIYPSLAPSARPLECTIQAGEALYFPDRWWHATLNLDTSVFISTFLG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TA59-1", "uniprot_id": "JMJD8_MOUSE", "id": "Q3TA59-1", "name": "JmjC domain-containing protein 8", "aln": "MAAAGRRGLLLLFVLWMMVTVILPAS---GEGGWKQNGLGIAAAVMEEERCTVERR--AHITYSEFMQHYAFLKPVILQGLTDNSKFRALCSRENLLASFGDNIVRLSTANTYSYQKVDLPFQEYVEQLLQPQDPASLGNDTLYFFGDNNFTEWASLFQHYSPPPFRLLGTTPAYSFGIAGAGSGVPFHWHGPGFSEVIYGRKRWFLYPPEKTPEFHPNKTTLAWLLEIYPSLALSARPLECTIQAGEVLYFPDRWWHATLNLDTSVFISTFLG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96S16-1", "uniprot_id": "JMJD8_HUMAN", "id": "Q96S16-1", "name": "JmjC domain-containing protein 8", "aln": "MAPASR-----LLALWALAAVALPGSGAEGDGGWRPGGPG---AVAEEERCTVERR--ADLTYAEFVQQYAFVRPVILQGLTDNSRFRALCSRDRLLASFGDRVVRLSTANTYSYHKVDLPFQEYVEQLLHPQDPTSLGNDTLYFFGDNNFTEWASLFRHYSPPPFGLLGTAPAYSFGIAGAGSGVPFHWHGPGYSEVIYGRKRWFLYPPEKTPEFHPNKTTLAWLRDTYPALPPSARPLECTIRAGEVLYFPDRWWHATLNLDTSVFISTFLG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1REV3-1", "uniprot_id": "A0A8M1REV3_DANRE", "id": "A0A8M1REV3-1", "name": "", "aln": "MDQILR-------ALLLLLIARLPASFQCSGAVSEDGGWGLDSSLQDEGECNIEIRDANSITHTEFINEYAYAKPVILRGLTDNTKFRFLCAKSSLLREYGDKTVRLSTANTHSYRKVDVRFEEFVKFLLTPQSEDTLGSDTLYFFGDNNFTEWRSLFEEYKAPPFSLPLTHPAYSFGIAGPGTGVPFHWHGPGYSEVIYGRKRWFLYPPDLAPEFHPNHTTLSWVSQSYLDLELHQRPLECTIRPGEVLYFPDRWWHATLNLDTSVFISTFLG", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* * .* : . **.* . . . . * :: :* .*.:* * :*::**::.**: :****:*****::** **::. ** .:**. ********:**:***: *:*:*: ** **. :**.************** .**..* .*** * * *********.*:**********:***************: :******:***:*: : * * *******:.**.*************************", "identical_positions": 158, "similar_positions": 56, "identity": "57.66%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120917-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CBC4-1", "uniprot_id": "CNST_MOUSE", "id": "Q8CBC4-1", "name": "Consortin", "aln": "MDDSDPPTYSLQIEPQDGCHPGDSVERRVTRLPSVSDENENQLAGDGPAGLTTSEGAMGRATVSEQDSLNNNESFPSSCEAAPTENAENTPSEGPKDDPPSLGQDQKLPAKRSPRAKKSSPKSAPP----GDAVPVMQT--QNATSQAAGEEEAAGVNANDPPKAP--ALQPLFSLIRGEVAQMDSRALPLFLHQVAETYFQEEDYEKAMKFIQLERLYHEQLLANLSAIQEQWETKWKAVQPRTVTPLRNSEKGFNGEDFEQLAKICTTHQDPLLSKLKTAPVEPSPERKSLARAIMSEEAVGTEAAAKEPEIETCPSTDPSGD-RHEEEPQESSPGCHQMEWQTASPELPGTAGKDHTEELPSSTNATLDLHTQSLETAGSRSGPAAASNACKDSSCVPAPPTEDHCGVAR------DPKVAPPSESVAEQKLSTGDDGALPGLISEGKYSQAHRKELCLPLQDAFEALPRDQPHSSEVAEPRQPDVTASDGKSAQSQAGLETGPESALCGDRKACDVSTLCLEVCMAPEERRDSEDRVSKETEDYLHSLLERCLKDAEDSLSYEDIQDDDSDLLQDLSPEEASYSLQEDLPPDESTLSLDDLAKKIEIAEAIPAEGLVSILKKRNDTVG--SHPAQMQQKPAKRRVRFQEIDDNLEQDEVGGGSCILLILLCIATVFLSVGGTALYCTLGNIESPVCTDFADNVDFYYTKLLQGVAGLKHWVYLS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6PJW8-1", "uniprot_id": "CNST_HUMAN", "id": "Q6PJW8-1", "name": "Consortin", "aln": "MDDSDTPTYYLQIEPQDGCHPGDSVERSVTCLPSASDENENQLDGDGHEHLTSSDSAMGKPQVSEQDSLNNNESCTLSCEVAAGENLQNTLCEASRDEQAFLGKDKKIPGKRSPRSKKGTAKKIPPGLFSGDIAPLMQEKVLSAVTYAVDDEEAAEVNANEQPEAPKLVLQSLFSLIRGEVEQLDSRALPLCLHQIAESYFQEEDYEKAMKFIQLERLYHEQLLANLSAIQEQWETKWKTVQPHTVTALRNSEKGFNGEDFERLTKICATHQDPLLSKHKIAAVEKSQERKCSTQLLVSEDPKEGGATTKESESKTCLGTESSKESQHTVEPLGSSPCCHQMDVQTDSPSLSVTAGKDHMEELLCSAEATLALHTQSSETAGSPSGPDSSEDACEDDSRLQLAQTEACQDVARIEGIAEDPKVFLSSKSKTEPLISPGCDRIPPALISEGKYSQAQRKELRLPLRDASEALPTDQLENNELNELQQPDLTDSDGKSPQAQADSD-GSENVLCGNNQISDLGILLPEVCMAPEEKGDKDDQLNKETEDYLNSLLEGCLKDTEDSLSYEDNQDDDSDLLQDLSPEEASYSLQENLPSDESCLSLDDLAKRIEIAEVVPTEGLVSILKKRNDTVG--DHPAQMQHKPSKRRVRFQEIDDSLDQDEVGGGSCILLVLLCIATVFLSVGGTALYCTFGDMESPVCTDFADNMDFYYTKLLQGVAELKHWIYLS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FE62-1", "uniprot_id": "E7FE62_DANRE", "id": "E7FE62-1", "name": "", "aln": "MDDGQ----WQSDGPVRRGGATEPELQSCSESFRSPDDNHNRLLEEADEVEQGPRGGHGPLRPELTNNNGDDEEYDSSKVEDEEEEDEEEVDSNSGAFSPELDGHIRDSPTPSPSP---------------------------TVSEGLLSPEDPPHSDSASPQGFSLSLTASLQELQ---EQGDHPLLPQCLHQIAEAFMHAEDYERAVRFIQLERLYHERLLFNLSALQMQWEKRLGLVG-RCQDGGGERDRNPDAEHLEKLRHICRTHRQPAWS------IEQSEASKVQKNSVIRAEQN------LNTHVLSCSSGNVMED-----------PSSSEAQQELSQPEDCSSSGIQRQHDHTPSSTATPTTPTLSLLAMPTSFSPSAVTDSSSSPDCEQKVNVPDSQ----------NYAEAQAPMDVSPSDQRPQTDNIGPAVMMEG---------TGITVDTGQDVPYTEMDDGGNVEESVKVEGGGEDG---------------------EALEQEVLEITAEMEMEENGNGLDFMN--------------------------------------------------------VAMLDDMAKRIQVEEITPAAGLVSILKRRVSLEGENSSAPAAPKPVSKRKVRFREPDEGLDHDEVAGDSWLLLLLLCLATVVISVGGTALYCSFGDTQSSVCTDFSHNMDFYVGRVQRGMDELKHWLSPSS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "***.: . * . :. : : .*:*.*:* :. . .. * . :. .::*. * *: :: . . . *. . : . . ** . :.: . . * . . . *:. * . :. :: * * ** ***:**:::: ****:*::**********:** ****:* ***.: * : : ::. :.*.:*:* :** **::* * :* * * . :: : :.. :* . : : * . : : : .*. ::* :: .: *: ** * * : : .* : ::... . . : .. . : . * *.:: ** :.: . :. : ...:: * : : .** : : * . * **. : * :. ***:**:*:: * *: *******:* . * . .. : :**:***:* *:.*::***.*.* :**:***:***.:*********::*: :*.*****:.*:*** :: :*: ****: * ", "identical_positions": 151, "similar_positions": 181, "identity": "20.71%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120919-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZBX5-1", "uniprot_id": "D3ZBX5_RAT", "id": "D3ZBX5-1", "name": "", "aln": "MSRLWTTKAGLVACGMICAFIF--LYLRSPGPE----EADAEPTRPAVVECGFYPDELCSALFEGKKAAPQIAQFCRPPRNSE-VLAHLSTPGNCSRMAQGLHFITRPLSAEEGNFSLAYVIHAPKELAMLVRLLRAIYAPQNVYCIHTDDKAPTKFKSAMQTFVGCFRNVFLSSKTQKVAHDNLRRLQAEIDCMRDLVRSPLQWRYVMNLGGQEFPIKTNKEIIHYIRT-RWKGKNITPGVTPPSNTKPKTGQSPPKPSSNENSYTSPNTRFKPKPPRNLTIHSGSAYYALTRNFVEFVLTDPRAKDMLQWSKDILSPEQHYWVTLNRLKDAPGATA-GAGWEGHIRATKQRTEAGDGHTGCTGHDAQDTCVYGLGDLPWLVQLPAFFA-TMEPSTDPLVVVCIERRHRLKALQQAKVPPEPHWQFPQESHFSSQAHD-------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3V3K7-1", "uniprot_id": "GCNT7_MOUSE", "id": "Q3V3K7-1", "name": "Probable beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7", "aln": "MSQLRTTKAGLVACGMICAFIF--LYLRNPGPEEAEAEAEAEPTNPAVVECGFYPDELCSALFDGKKAAPQIAQFCKPPQNSE-VPARLRTPGNCSRLARGLHFITRPLSAEEGNFSLAYVIHAPRELVMFVRLLRAIYAPQNVYCIHSDENAPKKFKSAMQTFVDCFGNIFLSSKTQKVAHDNLRRLQAEIDCMRDLVHSPFQWHYVMNLCGQEFPIKTNKEIIYDIRT-RWKGKNITPGVTPPANSKPKTGQGPPKPSPDENSYTAPNTIFKQSPPHNLTISSGSAHYALTRKFVEFVLTDPRAKDMLQWSKDIQSPEKHYWVTLNRLKDAPGATP-DAGWEGHIRATKWRTEAGDGRKGCTDHDAQDTCVYGLGDLPGLIRLPAFFA-TLEPSSDPLVGVCLERRHRLRALQQAEVPPEPHWQFPQQSHFNSQPHH-------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6ZNI0-1", "uniprot_id": "GCNT7_HUMAN", "id": "Q6ZNI0-1", "name": "Probable beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 7", "aln": "MSQLRATKSGLVVRAVICIFIF--LYLRNPTPA----ESEEEPAQPEVVECGFYPDELCSALFEGKGAAPQIAKFCKTPHKSE-IHAHLHTPGNCSRISRGLHFITRPLSAEEGDFSLAYIITIHKELAMFVQLLRAIYVPQNVYCIHVDEKAPMKYKTAVQTLVNCFENVFISSKTEKVAYAGFTRLQADINCMKVLVHSKFQWNYVINLCGQDFPIKTNREIIHYIRS-KWSDKNITPGVIQPLHIKSKTSQSHLEFVPKGSIYAPPNNRFKDKPPHNLTIYFGSAYYVLTRKFVEFILTDIHAKDMLQWSKDIRSPEQHYWVTLNRLKDAPGATP-NAGWEGNVRAIKRKSEEGNVHDGCKGRYVEDICVYGPGDLPWLIQSPSLFANKFEPSTDPLVVTCLERRHRLQVLRQAEVPIEPHWHFQQQSHFNMRLNR-------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BG25-1", "uniprot_id": "A0A8M2BG25_DANRE", "id": "A0A8M2BG25-1", "name": "", "aln": "MVQLENTKCSFLFCLGICTLICSAIYLKAKVAS------DPLPINDLTTLSPTPPPLPCPPSNTCDILPPATPGFKWQRKDCEKISYHIQPDTNCDLLLSQLHFITAPLSKEEEDYPLAFIITIHKELATFVRLLRAIYAPQNVYCIHIDQKASEKYKSSVRNLSRCFPNVFLSSVNVKVTYAGFSRLQADINCMKDLVESPIQWKKVINLCGQDYPIQTNLELVRYMQTPEWKDRNMTPGIKQPPSMRYRT---AFQYVEVKNTHVAQTGRKKGPPPHNLKIYFGTAYYSLTRPFVEYVLDNPVAKDLLSWSKDSYSPDEHYWVTLNHIKEAPGSNV-EGEWEGNVRAVKWSDQQGTAHQGCKGQYIRGICVYGIGDLPWLIEKESMFANKFEMASFPEALDCMELWHRHKVLQQATVPIQPSWHLTTEVEVVNRTLILTPGDCV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6T5E0-1", "uniprot_id": "Q6T5E0_RAT", "id": "Q6T5E0-1", "name": "", "aln": "---MPPSMRHFFIVSVTTVIVFIVLYVLSFGGD--------QSYQKLNISDSAMLAQVCTSFTNGK------NSFLWRN------KLMIHEKPSCTEYVTQSHYITAPLSQEEVEFPLAYVMVIHHNFDTFARLFRAIFMPQNVYCVHVDEKATAEFKGAVEQLVNCFPNAFLASKTEPVVYGGISRLQADLNCIRDLSTSEVPWKYAINTCGQDFPLKTNKEIVQYLKG--LKGKNLTPGVLPPAHAIGRTRYVHREHLSKEFSYVIRTAALKPPPPHNLTIYFGSAYVALSREFANFVLHDPRAVDLLHWSKDTFSPDEHFWVTLNRIPGVPGAMP-NASWTGNLRAVKWKDMESQ-NGACHGHYVHDICIYGNGDLQWLINSQSLFANKFEVNTYPLTVECLELRLRERTLNQSDIALQPSWHF-------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P97402-1", "uniprot_id": "GCNT2_MOUSE", "id": "P97402-1", "name": "N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase", "aln": "---MPPSVRYFFIVSVTTVIVFIVLYVLSFGGD--------QSYQKLNISDSVMLAQVCSSFIDGK------SRFLWRN------KLMIHEKPSCTEYVTQSHYITAPLSQEEVDFPLAYVMVIHHNFDTFARLFRAIFMPQNIYCVHVDEKATAEFKGAVEQLVSCFPNAFLASKMEPVVYGGISRLQADLNCIKDLSTSEVPWKYAINTCGQDFPLKTNKEIVQYLKG--LKGKNLTPGVLPPAHAIGRTRYVHREHLSKELSYVIRTTALKPPPPHNLTIYFGSAYVALSREFANFVLRDPRAVDLLHWSKDTFSPDEHFWVTLNRIPGVPGSMPPNASWTGNLRAVKWMDMEAK-HGGCHGHYVHGICIYGNGDLQWLINSQSLFANKFELNTYPLTVECLELRLRERTLNQSEIAIQPSWYF-------------------", "tax_id": 10090, "tax_name": "Mouse" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : : :. :: :*: . . *.. . * : .* *:** *** ** ::.**::: ::: :.:*:***: ***:**:* *::*. ::* ::. : ** * *::* *.: .: ****:::*:: * * . *. .:* **::*::** *:: :: ..:*:***: * :* : :. . * **:**.* *:*: *:* *.:::* : * *:* **** **::*:*****:: .**: . * *::** * . . .* .: .. *:** *** *:. ::** .:* : * . *:* * :.*.*: :. :* * : ", "identical_positions": 107, "similar_positions": 120, "identity": "23.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120920-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "E9QAM5-1", "uniprot_id": "HELZ2_MOUSE", "id": "E9QAM5-1", "name": "3'-5' exoribonuclease HELZ2", "aln": "MASVGCSLRSASTSATNGPSLAGLCAKVDLYLGCSRCTQCLNESTYILREVEHTCPREILLARFKQAAESKIWRKVGRRPSFPTPMRYQVCHYYRPGLGCRRHWNRCTFARSPEEALVWTFELKNNLPRLKLKEAVQGTRAPDRLQTPADTIRAEFGGHFQLLCAICFTCCPPCLCPVDPRGHCPKHQICPTLLIHVIVEG-LKRQFVEVRPLPQRRHPLNYCMYVGRGVPCRHGASRCEYAHSAVEMAVWKAEQLDGLQRGDLLTYPLFGENKWKASPNPNPPVTKLYCHACLVTCNSQEAFENHCSSLEHAQMVAFDQAVPWKHRAPPMGLSKFDLCPRPDLCEHGEVCIKAHSKQELQEWVQRAQDMELREQAAWQDGLVPYQARLLAEYQRSSKEVSVMAETIRGVSVTCHPPP-VHQAQEK-IQHQWVFTIHSEDPLLHVALLNQEPGAAFSLVAPSLPPHQLYAQGKHFCVQSSPAQYKVGVLVQAVAFGSFEQWVVFDFGRRPVLLQKLKLQLGQTHSQGLNGKPAPSHPQELEC----WHTGNRHVVLEVDWTPEQEALMAKYKLPSLALEFNQIVPDWGPISRSNYRQRMHKFLYEEEAAQQQLVAKLAMKGQVSLKTALETPALGMLFAPPGALYAKVPFHSSLLPDTDQGFLLSRAVSTALVAPVPAPNST--VYQVRLEARASSDHALWLLLPARCCMALGLQAQDSPILEVQFQIDPMTFRFWHQAVDALLEEHLVVPDLPACTLPHPWPTPPSFRGNHKQKLAVGLIAGRRPEGTKHIPPLLIYGPFGTGKTYTLAMAALEVVQQPHTKVLICTHTNSAADIYIREYFHDYVSSGHPEATPLRVMYADRPPRQTDPTTLQYCCLTEDRQAFRPPTGPELVHHRLVVTTTSQAR---ELQVPAGFFSHIFIDEAAQMLECEALIPLSYALSLTRVVLAGDHMQVTPRLFSVPRDKSARHTLLHRLFLYYQQEAHKIAQQSRIIFHENYRSTAAIINFVSHHFYLAKGNPIQASGKVPRHPQHYPLMFCHVAGSPEQDMSMTSWLNSAEVTQVVEKVREIYNTWPHCWGPREQRHICAVSHGAQVSALRQELRRRNLGEVSVGSFEILPGREFRVVVLSSVHNRNSLLSPGAPTSEFFTEPRVLNTVMTRAQSQLVAVGDAVALCS--SGACRNLWRSFIRECIEHHSAFPEELSLEQIEQGVAQRQNWASLTLKARGP-------------ETEQKSMAQGPQRLIAEGTMVTVKAETRAEAAAKAQTAAVAAEDTASGNSASRDAAAEVSTLEGGMS--EEDSESDFWPSDWELNADDAILKELLDESQQVTVTVREDGLLDTVVCS-APQKAREYTNLPSSVLWKFLRSNSKQFRRCSFLQETFERALATPLDDMASSPIQVRGRLNCGMAFTGDEVLVQILGPAGDDRCVPGSLQGRVMGVLKRRRHELAFVCRMDEWDPRIMIPINGSVTKIFVAEMKD-PQQVPIHRLIQGQVQRVRHETLKPEDRSTRLFWVRIVLWRERFYYPLGIVLEVLPKAITWEQGLYILDLEHGLKAHTPDPASVSKALQRYRSELNTAAGHREDYRHFLTFTVDPQGACNLDDALSVRDLGPVYEVAVHIADVASLVPKDGALDVEARQQGTVFYAPNREPVLMLPASLCQDALSLLPGQDRLAISLFLTMEKGGGQIKSLRFAPSIIRSDRQLSYEEAEELIKRHPGAGLELPAHLDSVEACVVAACYFSWMLRRQRLSAACYYEPPDEDSVLGFRTAHIMVQEYMIQFNSHVAEFLVSNKHTQTLTPLRWQPTPSRQQLDSVFKKYRGLVPLSLHLCHHSN----------TDYTPNKQLHLLTSLWKQVQLAAGTQDYSQMVDLIAADDMHPSLAPACLDLRRALGRSVFGRSSQGKQQPAVHHSLQVDWYTWATSPIRRYLDVVLQRLILLALGHRGSTYSNRDIDGLCLDFSRQYASAQSYQRRAYSLHLAIQLKSQPQNKLGFVVDVEMGARCFKVLFPINRETLPDPCPIHYHSLQLAEHPQELVSQTGVRLVWRRRMYSVQASKLPLPLLGTSLDPHTQTVDAALWMKLLMLLKEQRWPEIAALIQEQDKRF---HPREKVKIHQSRCG---------HFVEVVYELGSGDTLQVQLGSSLQRGFLAPTLKLWTVVPGFSLCLEHMERPGDCFSSHVHQALQDQYLQVGEYSGAWGPRCALESLTNAVTENDSIVLHDVHISWDTS---QGQLQGTFQLEAAFLQEKCINIHFGCCYLCIRLEGLPLPLDSSLPGPSGLGPFLNIDPNTYTWVAHGLSGDWDHELAGGDWDQENVDDRQEAPKQVYFLIHHMTMEKVPEEVLRPSARFTVEVLSKQLPDLRKEEAVRQLKTASPLVISIALGLPIPEIRWPISGPRRLVSELRWPIPGPRRPVSEPHRPMSGPCGPISEPCRSIPEPCRGNWPRQHSFHKASTSRFLERQNYNIPAGHHKLNQSQDRAVRSALQKQFTVIQGPPGTGKTVVGFHIVYWFHRSNQEQMPTDSSPSGEEQLGGPCVLYCGPSNKSVDVLGGLLLRRKTEMKPLRVYGEQAEATEFPLPGVSNRSLFGKTSQEGRPNQSLRSITLHHRIRQAPNPYAAEIRKFDAQLREGKIFSKEDLRVYRRVLGKARKHELERHSVILCTCSCAAS-KSLKILNVRQILIDEAGMATEPETLIPLVCFSKTVEKVVLLGDHKQLRPVVKSEQLQSLGMDRSLFERYHRDAIMLDTQYRMHKDICSFPSVEFYGGKLKTWSDLRRLPSILGHTGKPSCSVIFGSVQGHEQKLLVSTEDGNENSRANPEEVTQVVRIIKQLTLDRTVDPKDIAVLTPYNAQAAAISRGLMQRGVTGVTVTSITKSQGSEWRYVIVSTVRTCPRSDVDQRPTKSWLKKFLGFVVDPHQVNVAITRAQEALCIIGDHLLLRCCPLWHRLLDFCEAQHSLVSAEKVRVQRKSALSS---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9BYK8-1", "uniprot_id": "HELZ2_HUMAN", "id": "Q9BYK8-1", "name": "3'-5' exoribonuclease HELZ2", "aln": "MAPPGSTLLPNSPAATRGPSLARLCALVDLCLGCSRCTQRLNESTYVLRRVEHDCSREILLARFKQATKSKVWRVVGCRPTFPRPLCYQVCHYYSPGLGCRRHRNRCTFARSREEALVWTFERQHNLQRLWLKAEVQGSGAQGGAGRAADAILTEFGGRFELLCSLCFRRCPPCICRVDPQGQCPEHGACPSLLAHVSAEGRRKQQFVVVRPRPRAGQPPAYCRFVGRGQPCWRGESRCQFAHSAVEMAVWEAEQLGGLQRGDLLTPPAP-DGDGRTAPLGQPPGAQLYCPACLVTCHSQEAFENHCASSEHAQMVAFDQALPWEHRSPPPGLSKFELCPKPDLCEYGDACTKAHSAQELQEWVRRTQAVELRGQAAWQDGLVPYQERLLAEYQRSSSEVLVLAETLDGVRVTCNQPL-MYQAQERKTQYSWTFAVHSEEPLLHVALLKQEPGADFSLVAPGLPPGRLYARGERFRVPSSTADFQVGVRVQAASFGTFEQWVVFDFGRRPVLLQKLGLQLGQGRRPGPCRNLALGHPEEMER----WHTGNRHVVPGVERTAEQTALMAKYKGPALALEFNRSSVASGPISPTNYRQRMHQFLYEEEAAQQQLVAKLTLRGQVFLKTALQTPALNMLFAPPGALYAEVPVPSSLMPDTDQGFLLGRAVSTALVAPVPAPDNT--VFEVRLERRASSEQALWLLLPARCCLALGLQPEARLVLEVQFQIDPMTFRLWHQAVDTLPEEQLVVPDLPTCALPRPWSVPPLRRGNRKQELAVALIAGWGPGDGRRVPPLLIYGPFGTGKTYTLAMASLEVIRRPETKVLICTHTNSAADIYIREYFHSHVSGGHPEATPLRVMYTDRPLSQTDPVTLQYCCLTDDRQAFRPPTRAELARHRVVVTTTSQAR---ELRVPVGFFSHILIDEAAQMLECEALTPLAYASHGTRLVLAGDHMQVTPRLFSVARARAAEHTLLHRLFLCYQQETHEVARQSRLVFHENYRCTDAIVSFISRHFYVAKGNPIHARGKVPPHPRHYPLMFCHVAGSPDRDMSMASWLNLAEIAQVVEKVQEAYNTWPSCWGGREQRCICVVSHGAQVSALRQELRRRDLGQVSVGSFEILPGRQFRVVVLSTVHTCQSLLSPGALAPEFFTDARVLNTVLTRAQSQLVVVGDAVALCS--FGACGKLWESFIRECVERHSVCPEGLSMEQVEQGVAQRRRWPPRGTQAGAAGNWEAAPEPVGDLAEEQAAVVTAMVKAEPGDEALSPASRDITATTAQTEAAAAPAGDAVKEDVVPGACAAGAAAAAGVESTEAEDAEADFWPWDGELNADDAILRELLDESQKVMVTVGEDGLLDTVARPESLQQARLYENLPPAALRKLLHAEPERYRHCSFVPETFERASAIPLDDASSGPIQVRGRLDCGMAFAGDEVLVQLLS---GDKAPEGRLRGRVLGVLKRKRHELAFVCRMDTWDPRIMVPINGSVTKIFVAELKD-PSQVPIYSLRKGRLQRVGLERLTAEARHSRLFWVQIVLWRQGFYYPLGIVREVLPEASTWEQGLRILGLEYSLRVPPSDQATITKVLQKYHTELGRVAGRREDCRAFLTFTVDPQGACNLDDALSVRDLGPRCEVAVHITDVASFVPRDGVLDVEARRQGAAFYAPGREPVPMLPASLCQDVLSLLPGRDRLAISLFLTMEKASGQLKSLRFAPSVVQSDRQLSYEEAEEVIRQHPGAGRELPARLDSVDACVVAACYFSRLLRRHRLRSDCFYEQPDEDGTLGFRAAHIMVKEYMIQFNRLVAEFLVGSECTRTVTPLRWQPAPRSQQLKALCEKHGDRVPLSLHLGHHLHGG--------GGSPPDTRLHLLASLWKQVQFAARTQDYEQMVDLVTTDDMHPFLAPAGRDLRKALERSAFGRCARGHQQQGGHYSLQVDWYTWATSPIRRYLDVVLQRQILLALGHGGSAYSARDIDGLCQAFSLQHALAQSYQRRARSLHLAVQLKAQPLDKLGFVVDVEAGSRCFRLLFPSNRETLPDPCPVPYGSLQLAEHPHALAGRPGLRLLWRRRVYSAQGSSPPLPLPGTVPDPHTLAVETALWKQLLELVELQRWPEAAALIQEKGEAS---QRRELVQVQRSHCG---------HFLEVARELGSGDTLQVQLGTSLQHGFLVPSPQLWTVAPGFSLCLEHVERPGDCFSGRVYRAPRDRYRDVDEYACVWEPFCALESATGAVAENDSVTLQHLSVSWEASRTPQGQLQGAFRLEAAFLEENCADINFSCCYLCIRLEGLPAPTASPRPGPSSLGPGLNVDPGTYTWVAHGQT---------QDWDQERRADRQEAPRRVHLFVHHMGMEKVPEEVLRPGTLFTVELLPKQLPDLRKEEAVRGLEEASPLVTSIALGRPVPQP-----------------------------------------LCRVIPS------------------RFLERQTYNIPGGRHKLNPSQNVAVREALEKPFTVIQGPPGTGKTIVGLHIVFWFHKSNQEQVQPGGPPRGEKRLGGPCILYCGPSNKSVDVLAGLLLRR-MELKPLRVYSEQAEASEFPVPRVGSRKLLRKSPREGRPNQSLRSITLHHRIRQAPNPYSSEIKAFDTRLQRGELFSREDLVWYKKVLWEARKFELDRHEVILCTCSCAAS-ASLKILDVRQILVDEAGMATEPETLIPLVQFP-QAEKVVLLGDHKQLRPVVKNERLQNLGLDRSLFERYHEDAHMLDTQYRMHEGICAFPSVAFYKSKLKTWQGLRRPPSVLGHAGKESCPVIFGHVQGHERSLLVSTDEGNENSKANLEEVAEVVRITKQLTLGRTVEPQDIAVLTPYNAQASEISKALRREGIAGVAVSSITKSQGSEWRYVLVSTVRTCAKSDLDQRPTKSWLKKFLGFVVDPNQVNVAVTRAQEGLCLIGDHLLLRCCPLWRSLLDFCEAQQTLVPAGQVRVCRRPTMPS---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WF29-1", "uniprot_id": "X1WF29_DANRE", "id": "X1WF29-1", "name": "", "aln": "-----------MALAKNHYKLQALLQTYTLCVRCGRCCNKHNKISYSLNNIKHSCSENIVLIRRKQDGS--YWRPVAPLPNFPRPKKYVACWYYTKDRGCTRHGNNCQFASSSEEADLWNVMKDEKLTIPQIVNAIK-----------------------------------------------------------------------------QNQRTPQITFQEKRG---------------------------------------------------------PHDCTLCQVHFPTDEDFMNHCFTVKHRRRIFEDGNKTWKHREPPPTHKDLKLCERSLICEYGDNCTKAHSQEELQEWQTRVRAVRNKARDAASQGLLSYQDNLLDEYRHSKDKKMIMTDTIPDVFITCDRDLDAVYVRKRGIQCTWNFTIISKEPLEVIALLRREQGAKFSLSKK-PDEERSYSTSAWFEKRTEQTGHEIPVSFRSDQPGLYEQWVVFDFNTRPVLRQKLKVRVGEDDCQAAPAPEALLENPEAACNLEPWNEESMTIIPFVETEKAQRDLLNRYQLIMMNQQMN------GLINRENYKWSMHNFLYQEEKVVGELLSRLSLRGTVQLKNELSDDRFGMKWAHPGELFAAVPLSQPLTPDAPQGFIVKRHAIRSLVRVVKNNEYCGPIYEAEFLKDAASETQVHLQLSKRCCAALNLQNGEEYEMEVQFQVNRLWFCEMHKAIDDLPRMDKVLPDLKNAHLSISFQSDEG-EFNEKQQAAMDFVLG-VSDNRSSIPPLLIYGPFGTGKTRTLAKMAQALVQQPHNKILICTHTNSSADLYIKAHFHEYVRNGQLHARPLRIKAMEIKLASTDFITLQYCHLSREANCFEFPDKAVLDSTRIVITTTSLARFFNDMKLPENYFSHILIDEASQMLECEALMALSLAGNNTRVVLAGDHMQMGPKLFSVRPDKCSEHTLLNRLFYHYQAENSDVAKQSRIIFNENYRSTKDIVDFVSTHFYVGRSDVIKARGNVPSHPQQHALQFHHVRGECCLDPMSMSWFNAEQIVRVVHILQEIMKEWPQEWGAADPESVCVLSQGRQVLEIRYRLRLLGLPRFTVENAENVQGKQFRVIVISTVHTKDSLLETDRTCLEFFNDMRVLNTIMTRAQSQIFVVGDAAALSCHQFGMCWRLWRAYIEECINKESCH--DLTLDSLKQDLLEISKLCR---------------------------------------------SEDEENSDSESTTSELP-------------------------------------------DTEDLILQELLDESKEINVALTEEGLFPVFQNQEAFSSANN--QVAEVYYEEPMFTSSTVHKQCEIVKEGYDRGYAKPLDESTLR-IDIKGRANIGRAFPGDKVTVEILS------ATSHPPMGRVINILESADTVKEFVCALERHDNQVMTPINKCITKIFTPFWKDKPNHIAVRNPES--LKVEKFIKINEEAHRKSLFIVKVLSWRNVFRYPLGIVVGVLPKIATLDDGLHVLSIEYQLRRTLS---SSLRKQMQYLQRLDIFEKGRRDFRMLPTFTVDPAHSQDLDDAISLQDFGEYLEIGVHISDVASFVAKDSELDKFARQLCTTFYPREKEPIYMFPKELSTNLLSLIPNQDRRAISLIIEVDAQTNRIKRRFICKSVIHSNRKFSYDEVEDILENGE-------PLSDLLEICLVKVSNFAEVHRRYRKQDDWCYKMPDEDVTLGRRRSHQMVEELMVMFNHMVAERLLSDGATRSKTPLRCQDRPQTDKLIEIFDKNAALIPLSVHFSSQAHELNKQGLIQHNPQTDSDTFPVLKSILRCLKSAAEQENIYKIIDFVATDDIHPQLLPFAVAFRRLFHKACIQRSNSTHVSRIGHYDLDLDSYTWASSPVRRYLDVIVQRLLHSVIDKTDVKYTTLDINLSCLEFSRKNDQQSAYERKANALHFALKLSSQSERKVAYIVELNPLGTNFKVSFPLNRSSISENLDIMSRDLLLAVQPEFDVTNNSMILKWERRIYSFSNSHIHAEVKQQNPNSVMAYVPAKTWKCIADAIREQNWNAIFPLIEELQRNSGINARQFHETLSASKCTKNYDPLHAEHYAELYLRIKQGEAVEVQLGASTARGLMTPSIQLFVVHPKFEICVEHVRDPVKCFSEYALSSSRSSYNLYKDYQAIWRPMCEMESASSAVAENESILIVDVPLKWENSN--PKRLQGFFLLPLDKKSQWSIDCDLRNSFLCIRTR----IQKQSSPFLESAQNTALMDIPSFTWVVHGVIT------EAEETESKESTNQEPKSLRIDFLINHMPMTNIPEQIFHERTRFTLELIPKLLPDVRKENAIDSLTKANQLVKNIAMGRRITSDR----------------------------------------GCKIPNQ----------------NTGRFEINSY-HPSGLSHLNNSQSKAIREALTNPFTLIQGPPGTGKTVVGVHILYWLHKNIQQLQASGSKKR--------AILYCGPSNKSVDVVAGHLLHLRDHLKPLRVYSDQMEMLEFPYPGCN-LKLSRNSKRGEKPNTELSSIALHHLIRKEGNPFSTQIRAFDMKVQRGDQLTDEERKLFREILKKARKHELLHHDVILCTCTAASHPALAETLDFKQIIIDECAMATEPEAFIPLVAHK--PEQIVLLGDHKQLQPVVHCEVAERLGMSRSLFERYMENALMLDTQYRMQEDICAFPSNEFYGGRLQTGIPAK---SKLFLTQTKQTCIVFGHVEGKEKSLVVRTEQGNENSKANMEEAEEVVRVAILLTEAG-IKTKDIAILTPYNAQVAKISESLHNNHIRDITVNTIMRSQGSEWRYVIMSTVRSCPKSEIETQPPKSWIMKRLGFITDPHQVNVGITRAQEGLCIIGNENLLRCSSLWRKLLNHYQEKGCVVNPARLIQVRQPPRRTARR", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus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identical_positions": 940, "similar_positions": 834, "identity": "31.26%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120920-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0LF07-1", "uniprot_id": "A0ABK0LF07_RAT", "id": "A0ABK0LF07-1", "name": "mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase", "aln": "-----------------------------------------------------------MANENHGSPR--------------------EEASLLSHSPGTSNQNQPCSPKPVRLV----------------QDLPEELVHAGWEKCWSRRESRPYYFNRFTNQSLWEMPVLGQHDVLSDPLGLNATPLPQDSTLVETPPVENKPRKRQLSE--EQPSGNGVKKPKIEIPVTPTSQSVPSSPSIPGTPILKIWG-ASTEDKQ-------AALLRPTEVYWDLDIQTNAVIKHRGPSEVLPPHPEVELLRSQLILKLRQHYRELCQQREGIEPPRESFNRWMLERKVVDKGCDPLLPSNCEPVVSPSMFREIMNDIPIRLSRIKFREEAKRLLFKYAEAARRLIESRSASPDSRKVVKWNVEDTFSWLRKEHSASKEDYMDRLEHLRRQCGPHVSAAAKDSVEGICSKIYHISLEYVKRIREKHLAILKENNIPEE-VEASELEPRLVYCYPVRLAVSAPPMPSVEMHMENSVVCIRYKGEMVK------VSRSYFSKLWLLYRYSCVDDSAFERFLPRVWCLLRRYQMMFGVGLY---EGTGLQGSLPVHVFEALHRLFGVSFECFASPLNCYFRQYCSAFPDTDGYFGSRGPCLDFTPLSGSFEANPPFCEELMDAMVSHFEKLLESSPEPLSFIVFIPEWREPPTPALTRMEQSRFKRHQLVLSAFEHEYRSGSQHICKKEEMHYKAVHNTAVLFLQNDPGFAKWGPTPERLQELTAAYK-----------------------QSGR---SHGSSSSSSSSSS--EAKDRDSGREQGPS---REPHPT-------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P59114-1", "uniprot_id": "CAPAM_MOUSE", "id": "P59114-1", "name": "mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase", "aln": "-----------------------------------------------------------MANENHGSPR--------------------EGASLLSHSPGTSSQSQPCSPKPVRLV----------------QDLPEELVHAGWEKCWSRRESRPYYFNRFTNQSLWEMPVLGQHDVLSDPLGLNATPLPQDSSLVETPPVENKSRKRQLSE--EQPSGNGVKKPKIEIPVTPTSQSVPSSPSIPGTPTLKIWG-SSTEDKQ-------AALLRPTEVYWDLDIQTNAVIKHRGPSEVLPPHPDVELLRSQLILKLRQHYRELCQQREGIEPPRESFNRWMLERKVVDKGCDPLLPSNCEPVVSPSMFREIMNDIPIRLSRIKFREEAKRLLFKYAEAARRLIESRSASPDSRKVVKWNVEDTFSWLRKEHSASKEDYMDRLEHLRRQCGPHVSAAAKDSVEGICSKIYHISLEYVKRIREKHLAVLKENNIPEE-VEASELEPRLVYCYPVRLAVSAPPMPSVEMHVENSVVCIRYKGEMVK------VSRSYFSKLWLLYRYSCVDDSAFERFLPRVWCLLRRYQMMFGVGLY---EGTGLQGSLPVHVFETLHRLFGVSFECFASPLNCYFRQYCSAFPDTDGYFGSRGPCLDFTPLSGSFEANPPFCEELMDAMVSHFEKLLESSAEPLSFIVFIPEWREPPTPALTRMEQSRFKRHQLVLPAFEHEYRSGSQHICKKEEMHYKAVHNTAVLFLQNGPGFAKWGPTPERLQELTAAYK-----------------------QSGR---SHGSSSSSSSSSSSSEAKDRDSGREQGPS---REPHPT-------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H4Z3-1", "uniprot_id": "CAPAM_HUMAN", "id": "Q9H4Z3-1", "name": "mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase", "aln": "-----------------------------------------------------------MANENHGSPR--------------------EEASLLSHSPGTSNQSQPCSPKPIRLV----------------QDLPEELVHAGWEKCWSRRENRPYYFNRFTNQSLWEMPVLGQHDVISDPLGLNATPLPQDSSLVETPPAENKPRKRQLSE--EQPSGNGVKKPKIEIPVTPTGQSVPSSPSIPGTPTLKMWG-TSPEDKQQ------AALLRPTEVYWDLDIQTNAVIKHRGPSEVLPPHPEVELLRSQLILKLRQHYRELCQQREGIEPPRESFNRWMLERKVVDKGSDPLLPSNCEPVVSPSMFREIMNDIPIRLSRIKFREEAKRLLFKYAEAARRLIESRSASPDSRKVVKWNVEDTFSWLRKDHSASKEDYMDRLEHLRRQCGPHVSAAAKDSVEGICSKIYHISLEYVKRIREKHLAILKENNISEE-VEAPEVEPRLVYCYPVRLAVSAPPMPSVEMHMENNVVCIRYKGEMVK------VSRNYFSKLWLLYRYSCIDDSAFERFLPRVWCLLRRYQMMFGVGLY---EGTGLQGSLPVHVFEALHRLFGVSFECFASPLNCYFRQYCSAFPDTDGYFGSRGPCLDFAPLSGSFEANPPFCEELMDAMVSHFERLLESSPEPLSFIVFIPEWREPPTPALTRMEQSRFKRHQLILPAFEHEYRSGSQHICKKEEMHYKAVHNTAVLFLQNDPGFAKWAPTPERLQELSAAYR-----------------------QSGR---SHSSGSSSSSSSE---AKDRDSGREQGPS---REPHPT-------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0R4IKJ1-1", "uniprot_id": "CAPAM_DANRE", "id": "A0A0R4IKJ1-1", "name": "mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase", "aln": "-----------------------------------------------------------MTSENHTTIK--------------------ADSALVMSPTGSTSQAAPFSPSTSKPI----------------QELPDELIQAGWSKCWSKRENRPYYFNRFTNQSLWEMPVLGQHDVISDPLGLNAAPASGEANADAG--LGNGQRKRHPSEDASQAGPNSFKRPKVEIPATPTTPTVPISPSTPG---VKPWVNTTTDEKQGQASTPAPAPYRPSVVYWDLDIQTNAVIRERAPADHLPPHPEIELQRAQLTTKLRQHYHELCSQREGIEPPRESFNRWLLERKVVDKGLDPLLPSECDPVISPSMFREIMNDIPIRLSRIKYKEEARKLLFKYAEAAKKMIDSRNATPESRKVVKWNVEDTMNWLRRDHSASKEDYMDRLEHLRKQCGPHVASVAKDSVEGICSKIYHISAEYVRRIRQAHLTLLKECNISVDGTESAEVQDRLVYCYPVRLSIPAPPQTRVELHFENDIACLRFKGEMVK------VSRGHFNKLELLYRYSCIDDPRFEKFLSRVWCLIKRYQVMFGSGVN---EGSGLQGSLPVPVFEALNKQFGVTFECFASPLNCYFKQFCSAFPDIDGFFGSRGPFLSFSPASGSFEANPPFCEELMDAMVTHFEDLLGRSSEPLSFIIFVPEWRDPPTPALTRMEASRFRRHQMTVPAFEHEYRSGSQHICKREEIYYKAIHGTAVIFLQNNAGFAKWEPTTERIQELLAAYK-----------------------VSGRSLPSPGPSSTNTGEKDSKPAPERTAPSQDNSSPVDKTAQDTTNT----------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VPB7-1", "uniprot_id": "Q9VPB7_DROME", "id": "Q9VPB7-1", "name": "", "aln": "MAANNNNSIIHNLGAGTEGLLSSVIASTGTPGMGSSPVPSRASSSSASSAAQSAWDQLTASASNNMSPSPTAGAPTVTGPILPDNLGVGAGSSPVASCSSPSTPTKTHAPSPLESMGHTPQGPPTLGPGGYGEELTAELVNQGWRKFWSKRENRPYYWNKVTGESLWEMPGTRPFDPLTDPLGICHAGGP-------TPIIPNMHQQQQHQH------HHLKRRPSDDMHIHPNQHHMGGGP------PMKKFV----------LAGP-----------WDLEVCTNAVIVERPPTLLPQPHPEVEALRAAFTMKLLKTYEDLCMRRENIKAPRDSFNRWLMERKVIDTGCDPLLPSSCMPEISSSMYREIMSDIPIKIVKPKFTGDARKQLSRYAEAAKQIIESRSAPAESKKVVKWNVEDTFQWLRRTVGASYEDFQDRLAHLKRQCEPHLVETVKSSVETLCVKIYHLSADHARKIRERHSQLLKEHGIPEPTPPPPPPHLKKVWCYPIQFAVPSPRMPTIEYLQDRDHMIIKYTPATINQPDAQYINLTYLQKLEQLYRHNCFDDKKFDLFIGRVWCLLKRYQTFLGNALNSSQEAELTQAALPVPVFECLHRQFGVSFECFASPFNSYFRQYCSAFADTDAYFGSRGPFLDFKPVSGSFQVNPPHCEELIEASLLHIDKLLTDTMEPLSFIVFLPEWKS-----ISKLDDSMYKRRSMVVLGMAHEYRHGYQHMLQKSDVLIKCMQGTQVVWLQNSAGYARWGPNEIRVEALREAFRPQRDRERERAAAAAAAAGVTSSQQSPSTPPSAASTAPTTNSCTISGVNSNSSSTATTTSTSSSPSLTTTSSSMSPLSPHTPTGNPPPQFPMTISNTSSSSNLVAASPTMSVQSDCSSPSSSTMSLSPAPASGGYPDGVTSATAAAVSITATTTTSAAGAGSAFGQANSISSSASTQAVINSAV", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .*: : :: : ...:. . :*.. . : ::*. **:: ** * **:**.****:*:.*.:****** .* ::****: : . * :::: .. : ::*. :: *. : .* :* : ***:: ***** .* *: ***::* *: : ** : *.:** :**.*:.**:*****::****:*.* ******.* * :*.**:****.****:: : *: :*:: * :*****:::*:**.*..:*:**********:.***: .** **: *** **::** **: ..*.*** :* ****:* ::.::**: * :*** .*. .. . : *:***:::::.:* . :* :.. :::. :: :. ::.** ***:.*.** *: *: *****::*** ::* .: *. *.:*** *** *:: ***:*******:*.**:*:****.* *.:****** *.* * ****:.***.****::* : *:: ** : ******:*:***:. ::::: * ::*:.: : .: **** * **: ::.:: *.::.* *::***..*:*:* *. *:: * *:: * * .. :..:.. . .. : .* . * ", "identical_positions": 259, "similar_positions": 231, "identity": "26.84%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120920-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NEY1-1", "uniprot_id": "NAV1_HUMAN", "id": "Q8NEY1-1", "name": "Neuron navigator 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLGSSVKS------------VQPEV-----------------------------------------------------------------ELSSG---GGDEG---------ADEPRGAGRKAAAADGRGMLPKRAKAPGGGGGMAKASAAELKVFKSGSVDSRVPGGPPASNLRKQKSLTNLSFLTDSEKKLQLYEPEWSDDMAKAPKGLGKVG-------SKGREAPLMSKTLSKSEHSLFQAKGSPAGGAKTPLAPLAPNLGKPSRIPRGPYAEVKPLSKAPEAAVSEDGKSDDELLSSKAKAQ-------KSSGPVPSAKG---------QEERAFLKVDPELVVTVLGDLEQLLFSQMLDPESQRKRTVQNVLDLRQNLEETMSSLRGSQVTHSSLEMT-CYDSDDANPRSVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGSCRSEGTPAWYMHGERAHYSHTMPMRSPSKLSHISRLELVESLDS---DEVDLKSGYMSDSDLMGKTMTEDD---------------DITTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPSTPTASRRNSTIVLRTDSEKRSLAESGLSWFSE-SEEKAPKKLEYDSGSLKMEPGTSKWRRERPESCDDSSKGGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAGKP--EGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPS--TSGSFGYKKPPPATGTATVMQTG------GSATLSKIQKSSGIPVKPVNG--RKTSLDVSNSAEPGFLAPGARSNIQYRSLPRPAKSSSMSVTGGRGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPTKVASGRTTP--APVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPTATKLAELPPTPLR-------------ATAKSFVKPPSLANLDKVNSNSLDLPSSSDTTHAS-KVPDLHATSSASGGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSTPVPTPPAPPAAPTEEETEELTWSGSPRAGQLDSNQRDRNTLPKKGLRYQLQSQEE--TKERRHSHTIGGLPESDDQSELPSPPALPMSLSAKGQLTNIVSPTAAT-TPRITRSNSIPTHEAAFELYSGSQMGSTLSLAERPKGMIRSGSFRDP-TDDVHGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQGALNASETTPKELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWVYELRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSTSSSVGTDVTEGPAHPAPHTRLFHANEEEEPEKKEVSELRSELWEKEMKLTDIRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGSTPGQVPGS---------SALSSPRRSLGLALTHSFGPSLAD---TDLSPMDGISTCGPKEEVTLRVVVRMPPQHIIKGDLKQQEFFLGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSISHVKRVLDAEPPEMPPCRRGVNN---ISVSLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLVLSGPSGTGKTYLTNRLAEYLVERSGREVTEGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGIGDVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNVEPANGFLVRYLRRKLVESDSDINANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKAAWEDPVEWVRDTLPWPSAQQDQSKLYHLPPPTVGPHSIASPP--EDRTVKDSTPSSLDSDPLMAMLLKLQEAANYIESPDRETILDPNLQATL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8CH77-1", "uniprot_id": "NAV1_MOUSE", "id": "Q8CH77-1", "name": "Neuron navigator 1", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLGSSVKS------------VQPEV-----------------------------------------------------------------ELSGGSGSGGDEG---------ADESRGASRKAAAADGRGMLPKRAKAAGGSGSMAKASAAELKVFKSGSVDSRVPGGLPTSNLRKQKSLTNLSFLTDSEKKLQLYEPEWSDDMAKAPKGLGKLG-------PKGRETPLMSKTLSKSEHSLFQPKGGSTGGAKTPLAPLAPSLGKPSRIPRGPYAEVKPLSKAPEAAVSDDGKSDDELLSSKAKAQ-------KGSGTVPSAKG---------QEERAFLKVDPELVVTVLGDLEQLLFSQMLDPESQRKRTVQNVLDLRQNLEETMSSLRGSQVTHSSLEMP-CYDSDDANPRSVSSLSNRSSPLSWRYGQSSPRLQAGDAPSVGGSCRSEGPPAWYMHGERAHYSHTMPMRSPSKLSHISRLELVESLDS---DEVDLKSGYMSDSDLMGKTMTEDD---------------DITTGWDESSSISSGLSDASDNLSSEEFNASSSLNSLPTTPTASRRSSTIVLRTDSEKRSLAESGLNWFSE-SEEKTPKKLEYDSGSLKMEPGTSKWRRERPESCDDASKGGELKKPISLGHPGSLKKGKTPPVAVTSPITHTAQSALKVAGKP--EGKATDKGKLAVKNTGLQRSSSDAGRDRLSDAKKPPSGIARPS--TSGSFGYKKPPPATGTATVMQTG------SSATLSKIQKSSGIPVKPVNG--RKTSLDVSNSVEPGFLAPGARSNIQYRSLPRPAKSSSMSVTG-RGGPRPVSSSIDPSLLSTKQGGLTPSRLKEPSKVASGRSTP--APVNQTDREKEKAKAKAVALDSDNISLKSIGSPESTPKNQASHPPATKLAELPPTPLR-------------ATAKSFVKPPSLANLDKVNSNSLDLPSSSD-THAS-KVPDLHAPSSSTGGPLPSCFTPSPAPILNINSASFSQGLELMSGFSVPKETRMYPKLSGLHRSMESLQMPMSLPSAFPSSAPIPTP---PTAPSEEDTEELPWSGSPRAGQLDSSQRDRNTLPKKGLRYQLQSQEE--TKERRHSHTAGGLPESDDQAELPSPPALSMSLSAKGQLTNIVSPTAAT-TPRITRSNSIPTHEAAFELYSGSQMGSTLSLAERPKGMIRSGSFRDP-TDDVHGSVLSLASSASSTYSSAEERMQSEQIRKLRRELESSQEKVATLTSQLSANANLVAAFEQSLVNMTSRLRHLAETAEEKDTELLDLRETIDFLKKKNSEAQAVIQGALNASEATPKELRIKRQNSSDSISSLNSITSHSSIGSSKDADAKKKKKKSWVYELRSSFNKAFSIKKGPKSASSYSDIEEIATPDSSAPSSPKLQHGSTETASPSIKSSTSSSVGTEVTETPAHSVPHTRLFQANEEEEPEKKEVSELRSELWEKEMKLTDIRLEALNSAHQLDQLRETMHNMQLEVDLLKAENDRLKVAPGPSSGCTPGQVPGS---------SALSSPRRSLGLALSHPFSPSLTD---TDLSPMDGISTCGSKEEVTLRVVVRMPPQHIIKGDLKQQEFFLGCSKVSGKVDWKMLDEAVFQVFKDYISKMDPASTLGLSTESIHGYSLSHVKRVLDAEPPEMPPCRRGVNN---ISVALKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLVLSGPSGTGKTYLTNRLAEYLVERSGREVTDGIVSTFNMHQQSCKDLQLYLSNLANQIDRETGIGDVPLVILLDDLSEAGSISELVNGALTCKYHKCPYIIGTTNQPVKMTPNHGLHLSFRMLTFSNNVEPANGFLVRYLRRKLVESDSDVNANKEELLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPCFFLSCPIGIEDFRTWFIDLWNNSIIPYLQEGAKDGIKVHGQKAAWEDPVEWVRDTLPWPSAQQDQSKLYHLPPPSVGPHSTASPP--EDRTVKDSTPNSLDSDPLMAMLLKLQEAANYIESPDRETILDPNLQATL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB32TC96-1", "uniprot_id": "A0AB32TC96_DANRE", "id": "A0AB32TC96-1", "name": "Neuron navigator 1", "aln": "MSGGVNVKSLPRAQPGSGIPLHRTRLPSPKPEPKSNSSSLPRPSTHIPNRTTCSSSPTPISSRDLLRDSTLRNQHLLLRGSPPSQRSSTSSQTHSQDSRSAHSSPQVRRKESSFSRGTLDGSKTESWLDLRSNGNKNFQSGIFRSQPGQIDNGNLRSVISEQLKCHEESIASGSGQSKTGIPSFRFSNKNLRPGPAAANLEMSHLKVRRERVSLQNSASSSFSDEEMCTPDDLSPEIPQRPPPETAMPKQETSSVELLKTKQTPKVNMAAVAPFRYRLQIQEDISVDDFSDCSSDSIEVCCDDLNTGGMLGGSPRRQGVDLETEADKPPKAKTLQGQAGAKGVGGMAAKR-GKSGLPQATPRAELKVYRAGNSEGRLP---VPSNLRKQKSLTNLCVLTDAEKKMHLYQPKWSDDMEKPGTGQNKSGKLRDPGGSIGRGIPLS-KNLSKSEHSLFQ-------GKPKPFNPPS-RLGKPSRIPKSPYAEVKPISKAQEPAD--DSKSDDEILSSKAKANGKKSLSGTSGSATPGGDGGGKDGLEPEEGDKTFLKVDPELVVTVLGDLEQLLFSQMLDPESQRKRTVQNVLDLRQNLEETMSSLRGSQLSHSCIESSMCYDSDETNARSISSLSNRSSPLSWRQGQSSPRLQAGDAPSSG------------------VPAHSLPIRASAQIGHLQRIQLIESLDTTDDDLTQLKSAYLSDGNLTGKSQAEDDEDEEDDDVEVDDDDDDLANGWDESSSISSGLSDGSDNLSSEEFNAGSSLNSLPTTPIGSRRNSAIVLRTDAEKRSLVESGLSWYSEEGKTQCQTDGVYDTGSLKTDL-TSKWKKSRSQ--DDAAVKGELRKPQTLG----LKKSRNPPVGVTSPITHSSQSLLKVPGVPKNDQRVVDKAKMAVKSSGLQRSSSDAGKDRG-EHRKPPSGLVRPSAGTTNSFGYKKNTPTTGTATVLTTGPNTVPVDSTIVNKTPKTSGIPVKPSAGGGRKTSLDVSN-CDQGFMAPNARNNIQYRSLPRPAKTSTLSLTGGRPGARPVSSNIDIGLQGLKT-VPAPSRLKEPGKSSHRASTGGCTPVNQTDREKEKAKAKAVASDSECGGGGSLKNGTLTPTQCAPEPPSKLLGLRQPSSLGKYSELPSPNSHRPSSARSLSKPP---LLEKISSTSLECETTSPEDHLPPKVPPYSKVPDLSGQLISSSLSPTPAPVLSISSSQCFS--------SSSGSPSLYPRLSGLTRSMESLSLQMSVCP--PGGGTVDRG----------VSGGWTNGRASLSLTTDSSQKDRNTLPKKGLSQQLLSQAEEDSKERRHSHTIMSSTEASSPPQYPLP-----SLTGKLPLTNIMSPSSTSGTPRMTRSNSIPTHEASFELYQASPLGSTLSLAERPKSMIRSGSFRDRDNDDVHGSVLSLVSNASSSYSSAEERMQGEQIRKLRRELESSQEKVACLTTQLSANANLVAAFEQSLALMTSRLQTLSFSAEQKDGELIELKETIESLKTKNMEAQAVIQVALNNPDVAPKELRIRRQNSSESISSLNSITSHSSVGSLKD-DAKKKKKKSW---LRSSFGKAFSIKKGAKGGSMYSDIEEIATPDSSAPNSPKLAHEDGENPPPSLQSLQSAVS--------------SVILESNEETESDEKVVSELRSELWEKEMKLTDIRLEALNSAHQLEQLREAMNSMQSMVENLKAENDQLKTGSAPSSLVLPCGPPSSSTSQPSGLASLMSSNQTKPAMSLTKSFSLSLNECFTADVAPVELLSASCQRDEVFTRVVVRIADHQVSR-EARQQDFYIGSVKIHGKTEWSTLDSDIATIFRDYISQLDPGASMGLSVDSIHSYSINQSRRVLGTEDPENSPCDCLQAAPGLVTVTLKGLKEKCVDSLVFETLIPKPMMQHYISLLLKHRRLVLSGPSGTGKTYLTTRLAEYLLERSGRDPSSGLINTFNMHQQTCKDLQLYLSNLANQIDRDCGTDDIPLVIILDDISDATSITDIVNSALTCKYHKCPYVIGTTNQSFKMSSNHGLHLSFRMITFSNNVEPANGFLVRYLHRKLIETENNSKAHNSEVLRVLDWVPKLWYHLHTFLEKHSTSDFLIGPCFFLSCPVSLAEFRTWFIDLWNQSIIPYLQEGAKDGVKVHGQKAAWEDPVEWVRDTLPWPSAQQDQAKLFHLPPPTTCPNTAPAQQSNDERSHRDTALPTMESDPLMAMLLKLQESANYIESPERDISGNPTF----", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .*..* :.**: :*. * **. **:. * . *..:*: ** * .* :. *****:::*. :.*:* .************..***:***::**:*:***** *. .* .* * . ** ** *.********** * .*: * : ********:.*******:*** *.* *.*****:*******: ......*...* : :::********************************************************::**.:* . *****::*.**:************* ************** * :*::*:*:.:::.*:.*::*:****: * .:***.*:**.:* **: :*** *::.**************.***********.*******:** .***.*:******:*****.****.*:** .: : .. **:**** : ****::.*.: **:: ***:** :** ***.:.***.*******::** ***.* * : :..**.*:***.:**********:** : :*****:.*** *:.****** .*:******: ** .*: :.* *:******* * ********* : **:**.**.************:*::*:** * *.*****.** .* . * :******* * : :* :****************** **: . *: . **.: *..*.:. *. *:.* ::*:*: *** *:*:.*.**: ::* * . *** .. :* :.*.::*:***:*.*.*:. . * . .. :**:**** ******.: **: . *.. .: : . . :. : **.*:********** ** ** * :******** . .*:.. .: * * **:.* ****:**:::: ***:***********:****..* :***********.********* .**********.*.***:*********.****************** **:****************. *****: *: :**:** **::*:***: **.** ******* *** .:.:******:*****:*************:** ** ********** *****.********.*..* ***************.**** * . *...**::* *: : ::.:*** *.::* *****************************:****:*:.** *: ******:**....*** * *.* * :** : . .::*::.*. ** : :*::*:: :*:. ::** *****:. ::: : : :**:*::*. *: **.:*. **. : :*:****::**.:::***.:***.**:.: :***.:* ** .** ::*:**************************************************.******:*****: :.*::.*******:*****************: * .*:****:***:*:* **:::**.***********:******..**:.**********:*****************:***:*::.: :*::.*:*************************************:.: :**********:*************:*****************************:**:*****:. *:: .: ::*: :*:: :::*************:*******:*: :*.: ", "identical_positions": 1121, "similar_positions": 432, "identity": "49.38%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120921-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M391-1", "uniprot_id": "STING_RAT", "id": "F1M391-1", "name": "Stimulator of interferon genes protein", "aln": "MPYSNLHPSIPRPRSYRFKLAAFVLLVGSLMSLWMTGEPPSHTLHYLALHVASQQLGLLLKKLCCLAEELC-HVQSRYQGSYWKAVRACVGSPICFMALILLSFYFYCSLENTSDLRLAW-HLGILVLSKSLSMTLDLQSLAPAEVSAVCEEKNFNVAHGLAWSYYIGYLKLILP-----GLQARIRMFNQLHNNMLSGAGSRRLYILFPLDCGVPDDLSVADPNIRFRDMLPQQNTDRAGVKNRAYSNSVYELLENG-QPAGACILEYATPLQTLFAMSQDGKAG--FSREDRLEQAKLFCRTLEEILADVPESRNHCRLIVYQESEEGNSFSLSQEVLRHIRQEEKEEVTMSGPPTSVAPRPS----------------LLSQEPRLLISGMEQPLPLRTDLI---------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3TBT3-1", "uniprot_id": "STING_MOUSE", "id": "Q3TBT3-1", "name": "Stimulator of interferon genes protein", "aln": "MPYSNLHPAIPRPRGHRSKYVALIFLVASLMILWVAKDPPNHTLKYLALHLASHELGLLLKNLCCLAEELC-HVQSRYQGSYWKAVRACLGCPIHCMAMILLSSYFYF-LQNTADIYLSW-MFGLLVLYKSLSMLLGLQSLTPAEVSAVCEEKKLNVAHGLAWSYYIGYLRLILP-----GLQARIRMFNQLHNNMLSGAGSRRLYILFPLDCGVPDNLSVVDPNIRFRDMLPQQNIDRAGIKNRVYSNSVYEILENG-QPAGVCILEYATPLQTLFAMSQDAKAG--FSREDRLEQAKLFCRTLEEILEDVPESRNNCRLIVYQEPTDGNSFSLSQEVLRHIRQEEKEEVTMNAPMTSVAPPPS----------------VLSQEPRLLISGMDQPLPLRTDLI---------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q86WV6-1", "uniprot_id": "STING_HUMAN", "id": "Q86WV6-1", "name": "Stimulator of interferon genes protein", "aln": "MPHSSLHPSIPCPRGHGAQKAALVLLSACLVTLWGLGEPPEHTLRYLVLHLASLQLGLLLNGVCSLAEELR-HIHSRYRGSYWRTVRACLGCPLRRGALLLLSIYFYYSLPNAVGPPFTW-MLALLGLSQALNILLGLKGLAPAEISAVCEKGNFNVAHGLAWSYYIGYLRLILP-----ELQARIRTYNQHYNNLLRGAVSQRLYILLPLDCGVPDNLSMADPNIRFLDKLPQQTGDHAGIKDRVYSNSIYELLENG-QRAGTCVLEYATPLQTLFAMSQYSQAG--FSREDRLEQAKLFCRTLEDILADAPESQNNCRLIAYQEPADDSSFSLSQEVLRHLRQEEKEEVTVGSLKTSAVPSTS----------------TMSQEPELLISGMEKPLPLRTDFS---------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F4N7-1", "uniprot_id": "STING_DANRE", "id": "E7F4N7-1", "name": "Stimulator of interferon genes protein", "aln": "MSVMGEDALVPRARSRLPVMCAAGLGFLTLAVAWLLD--SDKFSERAGIIAFGLMLERFIYCICLLAEELLFHSRQRYHGRMSEIFRACFRG---SGILGMCAIFLMLMLGGVSFSVKQWSHFNLMCAGYMLLNSLGVLGPAPVEISEICEAKKMNVAHGLAWSFYIGYLKFLLP-----ALEVNVREYSRRER-----LSSPRLHILLPLNARVPSKPEEEDTNVVFHENLPDLKLDRAGVRKRSYTNSVYKITHN--NETFSCILEYATPLLTLYQMSQESSAG--FGERERKQQVLLFYRTLSQILDNSLECRNRYRLILLNDEHTGDPHYLSRELFQNLKQQDGEIFMDPTNEVHPVPEEGPVGNCNGALQATFHEEPMSDEPTLMFS---RPQSLRSEPVETTDYFNPSSAMKQN", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4LFY9-1", "uniprot_id": "STING_DROME", "id": "A0A0B4LFY9-1", "name": "Stimulator of interferon genes protein homolog", "aln": "-------MAIASNVVEAGNAVRAEKGRKYFYFRKMIGDYIDTSIRIVATVFLADLLLRLYRCVVEYGSNGRYYLPEDRLWIILRRSCTYNNRSIYLIVGFLLVAFFRISVTGNYRNVMPTTLFLFQMPLYWIWSFTDMDQSTLSYSHWIRDSHGLDYAAGMASNYFHGYLKLSLPERKDDGLKHRLAMYEDKNN---VTFGIKRLVILIPDEMFVNG--VLESHLLDKAEPLETQFINRAGVY-RPFKHDVYRMNKKVNGRTYYFAVEGATPMISFFDATYSNLSGTWQMQELKREIWIKFYKHLKELITTWPETRDLVELIIYNSHDSKGNLVDVGELLVAHMQNKTKTIDEISN----------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :. : . . . * : : ..: : . . : : :: : . : : : .: : : : :: * *:* .:: ***:: ** *: .: :. . ** **:* : * . . : : * ::**: * :.:.:*.: .: : :* ***: ::: : :* .. : : * : *.::: * :: .** :. . *:: *:. : . ", "identical_positions": 33, "similar_positions": 89, "identity": "7.86%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120926-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZA8-1", "uniprot_id": "D3ZZA8_RAT", "id": "D3ZZA8-1", "name": "", "aln": "---------------MAQPRIPAARGAAAGLQAQNGAAS------------------ASGSP-------------YTNGPVQHTLMSSQVSLSQGYDSQLPGSYPHPMPAKTLNPFSAQSNYGGSQGS-------GQALNSPLVTSSPVPPSLHSGPVPRMALPTSQNPAATPMPSGSFPPGTNP--APPLNWQYNHPSTGPQTNHFP-HVAQPTIPGNTDFTADHPYVSSGDPALQTSFKKPG-SALPLQNPPL---PPTFQP-----------GAPP----GPPPAGGPPPSR--GPVPQKTPPRAAFPPSLNSAVNQEGITSNANTG-SAAHSTYDEIEGGGFLATPQLVNQNPKTSRSV---GYAYP--SLPPGYQNTAPP------VAGMPPSSLN--YPSGPQAFTQAPLGANHLTASMSGLSLHPEGLRVVNLLQERNMLPSTPLQPPVPNLLEDVQK-LNCNPELFRCTLTSVPQTQALLNKAKLPLGLLLHPFKDLVQ----LPVVTSSTIVRCRSCRTYINPFVNFLDQ-RRWKCNLCYRVNDVPEEFMYNPLTRVYGEPHKRPEVQNATIEFMAPSEYMLRPPQPPVYLFVFDVSHNAIETGYLNSVCQSLLDNLDLLP-GNTRTKIGFITFDSTIHFYSLQEGLS-----------------------------QPQMLIVSDIDDVFIPMP-ENLLVNLNESKELVQDLLKTLPQMFTKTLETQSALGPALQAAFKLISPTGGRMSVFQTQLPTLGVGALKPREEPNQRSSAKEI-HLTPSTD-FYKKLALDCSGQQAAVDLFLLSGQYSDLASLGCISRYSAGSVYYYPSYHHQHNPVQVQKFQKELHRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLPNVNPDAGYAVQMSVEESLTDTQLVSFQSALLYTSSKGERRIRVHTLCLPVVSTLNEVFLGADVQAISGLLANMAVDRSVTASLSDARDALVNAVIDSLSAYRSSV-LSSQQPG--LMVPFSLRLFPLFVLALLKQKSFQTGTNVRLDERIFAMCQVKNQPLVHLMLTTHPSLYRVDNLSDEG-ALNIN---------DRTIPQPPILQLSVEKLSRDGAFLMDAGSVLMLWVGRNCAQNFLSQVLGVQNYASIPQTMTDLPELDTPES-ARMTAFISWLRE--QRPFFPILYVIR--------------EESLMKAAFLQNLVEDRTESALSYYEFLLHIQQQVNK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3U2P1-1", "uniprot_id": "SC24A_MOUSE", "id": "Q3U2P1-1", "name": "Protein transport protein Sec24A", "aln": "---------------MAQPRIPAARGAAASLQAQNGAAS------------------ASGSP-------------YTNGPVHNTLMSPQVSSSQGYDSQPPGSYPRPMPAKTLNPFSAQSNYGGSQGS-------GQTLNSPLVTSGPVLPSLHSGPVPRMPLPTSQNPAATPMPSGSFLPGANP--PPPLNWQYNYPSTGPQTNHFP-HVAPPTLPGNPNLTADHQYVSSGDPALQTSFKKPG-SALPLQNPPL---PPTFQP-----------GAPP----GPPPAGGPPPSR--GPAPQKTPPRAAPPPSFNSAVNQEGITSNANNGSTAAHNTYDEIEGGGFLATPQLVNQNPKTSRSV---GSAYP--SLPPGYQNSAPP------VAGMPPPSLS--YPSGPQAFTQTPLGANHLTASMSGLSLHPEGLRVVNLLQERNMLPSTPLQPPVPNLLEDIQK-LNCNPELFRCTLTSVPQTQALLNKAKLPLGLLLHPFKDLVQ----LPVVTSSTIVRCRSCRTYINPFVNFLDQ-RRWKCNLCYRVNDVPEEFMYNPLTRVYGEPHKRPEVQNATIEFMAPSEYMLRPPQPPVYLFVFDVSHNAIETGYLNSVCQSLLDNLDLLP-GNTRTKIGFITFDSTIHFYSLQEGLS-----------------------------QPQMLIVSDIDDVFIPMP-ENLLVNLNESKELVQDLLKTLPQMFTKTLETQSALGPALQAAFKLISPTGGRMSVFQTQLPTLGVGALKPREEPNQRSSAKEI-HLTPSTD-FYKKLALDCSGQQAAVDLFLLSGQYSDLASLGCISRYSAGSVYYYPSYHHQHNPVQVQKLQKELHRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLPNVNPDAGYAVQMSVEESLTDTQLVSFQSALLYTSSKGERRIRVHTLCLPVVSTLNEVFLGADVQAISGLLANMAVDRSVTASLSDARDALVNAVIDSLSAYRSSV-LSGQQPG--LMVPFSLRLFPLFVLALLKQKSFQTGTSIRLDERIFAMCQVKSQPLVHLMLTTHPSLYRVDNLSDEG-ALNIN---------DRTIPQPPILQLSVEKLSRDGAFLMDAGSLLMLWVGRNCSQNFLSQVLGVQNYASIPQTMTDLPELDTPES-ARIAAFISWLRE--QRPFFPVLYVIR--------------EESLMKAAFLQSLVEDRTESALSYYEFLLHIQQQVNK", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O95486-1", "uniprot_id": "SC24A_HUMAN", "id": "O95486-1", "name": "Protein transport protein Sec24A", "aln": "---------------MSQPGIPASGGAPASLQAQNGAAL------------------ASGSP-------------YTNGPVQNALLSSQESVSQGYNFQLPGSYPHPIPAKTLNPVSGQSNYGGSQGS-------GQTLNRPPVASNPVTPSLHSGPAPRMPLPASQNPATTPMPSSSFLPEANL--PPPLNWQYNYPSTASQTNHCPRASSQPTVSGNTSLTTNHQYVSSGYPSLQNSFIKSGPSVPPLVNPPL---PTTFQP-----------GAPH----GPPPAGGPPPVR--ALTPLTSSYRDVPQPLFNSAVNQEGITSNTNNGSMVVHSSYDEIEGGGLLATPQLTNKNPKMSRSV---GYSYP--SLPPGYQNTTPPG-----ATGVPPSSLN--YPSGPQAFTQTPLGANHLTTSMSGLSLQPEGLRVVNLLQERNMLPSTPLKPPVPNLHEDIQK-LNCNPELFRCTLTSIPQTQALLNKAKLPLGLLLHPFKDLVQ----LPVVTSSTIVRCRSCRTYINPFVSFLDQ-RRWKCNLCYRVNDVPEEFLYNPLTRVYGEPHRRPEVQNATIEFMAPSEYMLRPPQPPVYLFVFDVSHNAVETGYLNSVCQSLLDNLDLLP-GNTRTKIGFITFDSTIHFYGLQESLS-----------------------------QPQMLIVSDIEDVFIPMP-ENLLVNLNESKELVQDLLKTLPQMFTKTLETQSALGPALQAAFKLMSPTGGRMSVFQTQLPTLGVGALKPREEPNHRSSAKDI-HMTPSTD-FYKKLALDCSGQQVAVDLFLLSGQYSDLASLGCISRYSAGSVYYYPSYHHQHNPVQVQKLQKELQRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLPNVNPDAGYAVQMSVEESLTDTQLVSFQSALLYTSSKGERRIRVHTLCLPVVSTLNDVFLGADVQAISGLLANMAVDRSMTASLSDARDALVNAVIDSLSAYRSSV-LSNQQPG--LMVPFSLRLFPLFVLALLKQKSFQTGTNARLDERIFAMCQVKNQPLVYLMLTTHPSLYRVDNLSDEG-ALNIS---------DRTIPQPPILQLSVEKLSRDGAFLMDAGSVLMLWVGKNCTQNFLSQVLGVQNYASIPQPMTDLPELDTPES-ARIIAFISWLRE--QRPFFPILYVIR--------------DESPMKANFLQNMIEDRTESALSYYEFLLHIQQQVNK", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1PSG8-1", "uniprot_id": "A0A8M1PSG8_DANRE", "id": "A0A8M1PSG8-1", "name": "", "aln": "---------------MSSGQFAPQNGAGDSFA--NGPSQ------------------NAVYP-------------LNPGFMAPPLQPGYISSVPAKGLPAGPQSCYNTHRHQPSPVGTHSPLPASPNH-------RPVLPGPPQAS-PTPPPHANSHYQHTQQPSSWSSTAAVFQSTAAPPALNV--MAPH--QTFGPPPAAMRGTPPLTVPPPTVAP-PPFAAAPPPSTIAPPPFAAAPPPSTIAPPPFAAAPP---PSTIAPP-------PFVAAPPPSTIAPPPFAGAPPTS--TVLPP--PRAGVPPPSASAAVPPPPTGAHSDAGPYHLGQMSRPVGSGYPSLQPGYSTAQGYTPPVG---QIQHPPGQIQPSSMGQIHP------TAQIPPPSAGQFHPAGQIPPSAQQAGLSPSLAALSLQSHTPEALRVLNLLQERNLLPHTAVTPPLPCLPQDLQR-MNCSPEVFRCTLTSIPQTQALLNKAKLPLGLLLHPFKDLSQ----LPVVTSSNIVRCRSCRTYINPFVTFVGP-TRWKCNLCHRINEVPEEFMYNPVSKSYGAPHKRPEVQNATIEFIAPSEYMLRPPQPAVYLFVLDVSHNAVETGYLDAVCRSLLDNLSSLP-GDARTKIGFITFDSTIHFYSLQEGLS-----------------------------RPQMLIVSDIDDVFLPTQ-DGLLVNLNECKELVQDLLSSLPQMWRQTMETHSALGPALQAAFKLLSATGGRISLFQTQLPTLGIGALKPREQPSTKTQAKDIQHLSPATD-FYKKLALDCSGQHVAVDLFLLSAQYCDLSSLGCISRYSAGSVFYYPSYHTLHNPAQAERFQKDLKRYLTRKIGFEAVMRIRCTKGLSIHTFHGNFFVRSTDLLSLANVNPDAGFAVQMNIEENLLDLQTVSFQAALLYTSSKGERRIRVHTLCLPVVNSLSDIFAGADVQAITALLASMAVDRSVTASVSDARDALVNAAVDMLSSYRSSV-LTVPQPG--LLAPACLRLFPLYILALLKHKAFGTSSATRLDERMFCMCQLKQQPLAYAMLSIHPSLYRVDDLTDEG-ALNVN---------DCTIPQPRVQQLSVEKLSRDAAFLMDCGSVLYLWIGRNCNPAFLTQVLGVDGYANIPLNMTQLPELDTAES-CRMRAFVDWLRE--RRPFHPLLHVIR--------------DESPLKAEFLQLMIEDRSESALSYYEFLLHLQQQSSK", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A1Z813-1", "uniprot_id": "A1Z813_DROME", "id": "A1Z813-1", "name": "", "aln": "MSTYNPNFVPPAHAPMPLNGNNFVNGVQGSVQQQPGPPPGQQYIPQKQPQQFQQPPPAAAFPGAGAPGNVPPPQQFNSGITNQFLPPTSGAATPLQQLPPSTLPPHLRPPAANGPPLTNGSNGASSANSSRTASPRPVGAAPQYAQGPIAAALNNPPLASGLRPSPQPTHQSLANLTSNLENLNLNTTRANGGTSILPQPQTQQQYAP-TVTQKDGRGVASAQTGPPQFNDANSLLAASGVAAALVPNAMATPFSGQKPPNLAPNPAKMFGSASMAGRPTPAGQRIPYGVPPPTNPEQQSQQNNNLQNAPPPPRVGAVWPPSLPNVAAPGAQPMMPPAQQTPQTYPYSQVYQPGPQQQPPPPQ---SAVQP---PPPGMFGTQPTGAPLQYQAQAPPQAYGQHPQQAPQTAPGGPYGTTAPLNVAQQGFSRLWGQDTIDLMQNRHILTPATLPPPKVVLHNQFHESINCSPSIMRCTLTKIPESNSLLQKSRLPLGIVIHPFRDVNS----LPVIQCINIVRCRLCRTYINPFVYFVDS-KMWKCNLCYRVNELPDDFQFDPATKTYGDVTRRPEVRSSTIEFIAPSEYMLRPPQPAMYLFLFDVSIIAQQSGYLEAACAVLNRHLDEMP-GDARTQVGFICFDSFVHFYSMAEGLN-----------------------------QPHEMTLLDIEDPFLPRP-DSLLVNLKECKELVRDLLKQLPKRFAHTHDPGSALGAALQVAFKLMQASGGRITVFQSCLPNKGPGALEPREDPNNRS-AKDVAHLNPATD-FYKRFALECSGYQIACDLFLMNQQYSDMATISGISKHSGGCVHHFPLYQKTK-PHMVESFRSCFKRYLTRKIGFEAVMRIRCTRGLQVHTFHGNFFVRSTDLLSLPNVNPDAGYGMQISYEESLTDAKTICFQAALLYTNSEGERRIRVHTVCLPVTASLPEVMHSADTEAIIGLLSKMAVDRSVASNLSDARDAFINATIDVYNAFKIAQNLPSGQSGQ-LIAPRSLALLPLYILALLKHPAFRVGTSTRLDDRVYAMDCMKTLPLDQLMKYVYPELYKIDALIYHARNSNISSNQDDDEDEDEPLPELPRLQLSAEHLDSRSIFLMDCGTLIMIYVGLNVPPDVLEAVLGISSTAELGDYVYGLPNVVSNEN-DVLKRFILRLNY--DKPYSALVQIIR--------------DTSTAKGQFTERLTDDRSESSLSYYEFLQHIRAQVK-", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53953-1", "uniprot_id": "SFB2_YEAST", "id": "P53953-1", "name": "SED5-binding protein 2", "aln": "------------------------------------------------------------------------------------MSHHKKRVYPQAQVPY----------------------------------------------------IASMP----IVAEQQQSQQQIDQTAYAMGNLQL------------------------------------------------------------------------------------------------------------------------------------------NNR----ANSFTQ----------LAQNQQ---FPGSG--------------------------------------------------------KVVNQLYPVDLFTELPPPIRDLSLPPLPITISQDNIVTP--------SEYSNVPYQYVRSTLKAVPKTNSLLKKTKLPFAIVIRPYLHLQDSDNQVPLNTDGVIVRCRRCRSYMNPFVVFINQGRKWQCNICRFKNDVPFGFDQNLQGAPI-NRYERNEIKNSVVDYLAPVEYSVREPPPSVYVFLLDVSQNAVKNGLLATSARTILENIEFLPNHDGRTRIAIICVDHSLHYFYVPLDDDYEVSDEDDEESDGEEEDEDEEEEDVDNSETIQMFDIGDLDEPFLPMPSDELVVPLKYCKNNLETLLKKIPEIFQDTHSSKFALGPALKAASNLIKSTGGKVEVISSTLPNTGIGKLKKRSEQGILNTPKESSQLLSCKDSFYKTFTIECNKLQITVDMFLASEDYMDVATLSHLGRFSGGQTHFYPGFNATS-LNDVTKFTRELSRHLSMDISMEAVMRVRCSTGLRATSFFGHFFNRSSDLCAFSTMPRDQSYLFGISIEDSLMAEYCYLQVSTLLTLNT-GERRIRVMTLALPTSESAREVFASADQLAITDFMTQNAVTKALNSSMYSARDFITKSLEDILNAYKKEISMSNINSVTSLNLCANLRMLPLLMNGLSKHIALRPG-VVPSDYRASALNRLETEPLHYLIKSIYPTVYSLHDMPDEVGLP----------DFEGKTVLPEPINATISLFERYGLYLIDNSAELFLWVGGDAVPELLIDVFNTDTISQIPVGKSELPLLNDSPFNERLRRIIGRIRENNDTITFQSLYIIRGPSINEPANLNSEKDMASLRLWVLSTLVEDKVLNCASYREYLQSMKTSINR", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40482-1", "uniprot_id": "SEC24_YEAST", "id": "P40482-1", "name": "Protein transport protein SEC24", "aln": "------------------------------------------------------------------------------------MSHHKKRVYPQAQLQYGQNATPLQQPAQFMPPQDPAAAGMSYGQ----------------MGMPPQGAVPSMGQQQFLTPAQEQLHQQIDQATTSMNDMHL------------------------------------------------------------------------------------------------------------------------------------------HNVPLVDPNAYMQPQVPVQMGTPLQQQQQPMAAPAYGQPSAAMGQ----------------------------------------------NMRPMNQLYPIDLLTELPPPITDLTLPPPPLVIPPERMLVP--------SELSNASPDYIRSTLNAVPKNSSLLKKSKLPFGLVIRPYQHLYDDIDPPPLNEDGLIVRCRRCRSYMNPFVTFIEQGRRWRCNFCRLANDVPMQMDQSDPNDPK-SRYDRNEIKCAVMEYMAPKEYTLRQPPPATYCFLIDVSQSSIKSGLLATTINTLLQNLDSIPNHDERTRISILCVDNAIHYFKIPLDS------ENNEES----------------ADQINMMDIADLEEPFLPRP-NSMVVSLKACRQNIETLLTKIPQIFQSNLITNFALGPALKSAYHLIGGVGGKIIVVSGTLPNLGIGKLQRRNESGVVNTSKETAQLLSCQDSFYKNFTIDCSKVQITVDLFLASEDYMDVASLSNLSRFTAGQTHFYPGFSGKN-PNDIVKFSTEFAKHISMDFCMETVMRARGSTGLRMSRFYGHFFNRSSDLCAFSTMPRDQSYLFEVNVDESIMADYCYVQVAVLLSLNN-SQRRIRIITLAMPTTESLAEVYASADQLAIASFYNSKAVEKALNSSLDDARVLINKSVQDILATYKKEIVVSNTAGGAPLRLCANLRMFPLLMHSLTKHMAFRSG-IVPSDHRASALNNLESLPLKYLIKNIYPDVYSLHDMADEAGLPVQT----EDGEATGTIVLPQPINATSSLFERYGLYLIDNGNELFLWMGGDAVPALVFDVFGTQDIFDIPIGKQEIPVVENSEFNQRVRNIINQLRNHDDVITYQSLYIVRGASLSEPVNHASAREVATLRLWASSTLVEDKILNNESYREFLQIMKARISK", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . . : . : * :. : * . * . .*.**. :*:..:**:*::**:.::::*: .: . *: ***** **:*:**** *: *:**:* *::* : . * *:: :.::::** ** :* * *. * *::*** : :.* * : : ::. :* : **::.:: .* :*:: : . : : : *::: *:* : ::* *: .:: :. **. :*: : . . ***.**: * :*: **:: :.. **. * * *: *.: . . .*: :: .. * *** ::::*. : : *:** . :* *::::. :.:.:.* ...:* : : : :::: .: :*:*** * : ** *.*:** **:** ::..: * .: . :. ::.: :.** .. .:****: *:.:*. : :: .** ** : . ** ::: :.: .** : :: * ::: :. * * ::** : .* *: :: . * * .: :: ** : :* :* :. : . : : . :. . :*:* . : :::* : .: *:. . .: :* : : :: :. : ::* : : : . : :*: . ** *:* :: . ", "identical_positions": 146, "similar_positions": 266, "identity": "11.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120926-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A096MJF9-1", "uniprot_id": "A0A096MJF9_RAT", "id": "A0A096MJF9-1", "name": "", "aln": "MAPGMLGRRGAALLC-LSVLLAHAASRSHPAS-------PSPPGPQASP--VLPVSYRLSHTRLAFFLKEARPPTPTAMNGS-LQRSEPFVVFQTKELPVLNVSLGPFSTSQVVARELLQPS------------STLDIPERLTVNWKVRAFIVRARVPASQPVAQVLFYVAGRDWDDFGVTERLPCVRLHAFRDAREVRSSCRLGGALATCLVRAELPLAWFGPPAPAAPPSTRRKSPDGLEPEATAESQQVELYYTLHAPDAAGGCGSARRGSGPGP--AARAESPTQHPLLRIGSISLFRPPPRRAMQEHRLDSNLMIRLPDRPLRPGEVLSILLYLAPNSSSAASPSLEHFTLRVKAKKGVTLLGTKSRNGQWHVTSELLTGAKHSTATVDVAWAQGTPLPPWESQGP---LEILQLDFEMENFTSQSVKR-RIMWHIDYRGHSALP-----------DLERAVTELTVIQRDVQAILPLAMDTEIINTAILTGRTVAIPVKVIAIEVTGVVLDVSDLVECQSHREDIIKVSSSCDYVFVSGKESRGSMNARVTFRYDVLSAPLEMTVWVPKLPLHIELSDARLSQVKGWRVP----ILPDRRSARESE------DEEEEEEERRQSANRGCTLQYQHATLQVFTQFHTTSSEGTEQVVTMLGPDWLVEVTDLVSDFMRVGDPRVAHLVDSNTLAGLEPGTTPFKVVSPLT-EAVLGETLLTVTEEKVSITQLQAQVVASLTLSLRPSPGSSHTILATTAAQPTLSSVKQEALLSLWLSYSDGTTAPLSLYSPRDYGLLVNSLDERVATVTQD--KAFPLLVAEAEGAGDLLRAELTISESCQKTK-----------RKSVLATTPVGLRVHFGRDEE-------DPTYDYPGPSQPGPGGGEDEARGAGPPGTAIPAGEVPGLGTAGP-MPPTEDFLPLPTG---FLQMPRGLTDLEIGMYALLGVFCLAILVFLINCIVFVLRYRHKRIPP----------------------EGQTSMDHSHHWVFLGN------------------------------------------GQPLRVQGELSPPAG-------------------------------------------------------------------------------------------SALETVPACCHGDHHS---------------------------------------------------------------------SGSSQTSVQSQVHGRGDG------SSGGSARDQ---------TEDPASSPTSKRKRVKFTTFTTLPSEELAYDS-VPAGEEDEEDEEDLGWGCPDVAGTTRPTPPPDLHNYMRRIKDIA--------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q6IEE6-1", "uniprot_id": "T132E_MOUSE", "id": "Q6IEE6-1", "name": "Transmembrane protein 132E", "aln": "MAPGMSGRRGAALLC-LSVLLAHAASRSHPAS-------PSPPGTQASP--ILPVSYRLSHTRLAFFLKEARPLTPAAINGS-LQRSEPFVVFQTKELPVLNVSLGPFSTSQVVARELLQPS------------STLDIPERLTVNWKVRAFIVRARVPASQPVAQVLFYVAGRDWDDFGVTERLPCVRLHAFRDAREVRSSCRLGGALATCLVRAELPLAWFGPPAPAAPPSARRKSPDGLEPEAAAESQQVELYYTLHAPDASGGCGSARRGPGPGPGAAARAESPTQHPLLRIGSISLFRPPPRRAVQEHRLDSNLMIRLPDRPLRPGEVLSILLYLAPNSSSAASPSVEHFTLRVKAKKGVTLLGTKSRSGQWRVTSELLTGAKHSTATVDVAWALDTPLPPWEGQGP---LEILQLDFEMENFTSQSVKR-RIMWHIDYRGHSALP-----------DLERAVTELTVIQRDVQAILPLAMDTEIINTAILTGRTVAIPVKVIAIEVTGLVLDVSDLVECQSHSEDIIKVSSSCDYVFVSGKESRGSMNARVTFRYDVLSAPLEMTVWVPKLPLHIELSDARLSQVKGWRVP----ILPDRRSARESE------DEEEEEEERRQSANRGCTLQYQHATLQVFTQFHTTSSEGTDQVVTMLGPDWLVEVTDLVSDFMRVGDPRVAHLVDSNTLAGLEPGTTPFKVVSPLT-EAVLGETLLTVTEEKVSITQLQAQVVASLTLSLRPSPGSSHTILATTAAQPTLSLVKQEALLSLWLSYSDGTTAPLSLYSSRDYGLLVSSLDERVATVTQD--KAFPLVVAEAEGSGDLLRAELTISESCQKTK-----------RKSVLATTPVSLRVHFGRDEE-------DPTYDYPGPSQPGPGGGEDEARGAGPPGTAIPAGEVPGLGTAGP-VPPTEDYLPLPTG---FLQMPRGLTDLEIGMYALLGVFCLAILVFLINCIVFVLRYRHKRIPP----------------------EGQTSMDHSHHWVFLGN------------------------------------------GQPLRVQGELSPPAG-------------------------------------------------------------------------------------------SALETVPACCHGDHHS---------------------------------------------------------------------SGSSQTSVQSQVHGRGDG------SSGGSARDQ---------TEDPASSPTSKRKRVKFTTFTTLPTEELAYDS-VPAGEEEDE-EEDLGWGCPDVAGTTRPTPPPDLHNYMRRIKDIA--------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IEE7-1", "uniprot_id": "T132E_HUMAN", "id": "Q6IEE7-1", "name": "Transmembrane protein 132E", "aln": "MAPGMSGRGGAALLC-LSALLAHASGRSHPAS-------PSPPGPQASP--VLPVSYRLSHTRLAFFLREARPPSPAVANSS-LQRSEPFVVFQTKELPVLNVSLGPFSTSQVVARELLQPS------------STLDIPERLTVNWKVRAFIVRSHVPASQPVVQVLFYVAGRDWDDFGVTERLPCVRLHAFRDAREVKSSCRLSGGLATCLVRAELPLAWFGPPAPAAPPTARRKSPDGLEPEATGESQQAELYYTLHAPDASGGCGGSRRGAGPGVG--ARAESPTQHPLLRIGSISLFRPPPRRTLQEHRLDSNLMIRLPDRPLKPGEVLSILLYLAPNSSSPSSPSVEHFTLRVKAKKGVTLLGTKSRSGQWHVTSELLTGAKHSTATVDVAWAQSTPLPPREGQGP---LEILQLDFEMENFTSQSVKR-RIMWHIDYRGHGALP-----------DLERAVTELTVIQRDVQAILPLAMDTEIINTAILTGRTVAIPVKVIAIEVNGLVLDISALVECESDNEDIIKVSSSCDYVFVSGKESRGSMNARVTFRYDVLNAPLEMTVWVPKLPLHIELSDARLSQVKGWRVP----ILPDRRSVRESE------DEDEEEEERRQSASRGCTLQYQHATLQVFTQFHTTSSEGTDQVVTMLGPDWLVEVTDLVSDFMRVGDPRVAHMVDSSTLAGLEPGTTPFKVVSPLT-EAVLGETLLTVTEEKVSITQLQAQVVASLALSLRPSPGSSHTILATTAAQQTLSFLKQEALLSLWLSYSDGTTAPLSLYSPRDYGLLVSSLDEHVATVTQD--RAFPLVVAEAEGSGELLRAELTIAESCQKTK-----------RKSVLATTPVGLRVHFGRDEE-------DPTYDYPGPSQPGPGGGEDEARGAGPPGSALPAPEAPGPGTASPVVPPTEDFLPLPTG---FLQVPRGLTDLEIGMYALLGVFCLAILVFLINCIVFVLRYRHKRIPP----------------------EGQTSMDHSHHWVFLGN------------------------------------------GQPLRVQGELSPPAG-------------------------------------------------------------------------------------------NPLETVPAFCHGDHHS---------------------------------------------------------------------SGSSQTSVQSQVHGRGDG------SSGGSARDQ---------AEDPASSPTSKRKRVKFTTFTTLPSEELAYDS-VPAGEEDEEEEEDLGWGCPDVAGPTRPTAPPDLHNYMRRIKEIA--------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "L7VG99-1", "uniprot_id": "T132E_DANRE", "id": "L7VG99-1", "name": "Transmembrane protein 132E", "aln": "MGHFVVQGDLPWILCSLRLVIMIIAGKVSPTSSDALFSVPVPSATSSPPEVYLPATFKLSNTQLAFFLQENRAPSYGSQRGHPLQRSESFVVFQTKELPAVNISLGPFTQDQTLSKDLLQPS------------SPLDIPGRLTVNWKVRAFIVQSRVYASNPLVQVLFYIAGRDWDDFKIQDKLPCVRLHAFRDVREIKTSCRLQGNLAQCLAQLDLPSTWFN---VNVAPLGRRKSSGTDGLELTGETLQVELYYTLHDPDSNDECGESYPRRGGPS----RGESLSQQPLLRIGSISLYQPSQEQLVVDKQLDKNLFLRLPERPLKPGETLNIYLLLVPNS------TVEQFTLKVKAKKGVNLLSTKSRSNQWRVEWDMQSGAKHSIATVEASKIKGVSG---DMAGS---IEIMQLDFEMENFTSQSVTR-RINWNIDYRGQNPTS-----------DAEKVVTELTVVQKDIQAIIPLSMDTEIINTAVLTGRTVAIPVKVVSIELNGAVTDVSSSVQCKSFNEDIVKVSMNCDYVFVNGKETRGSMNARVIFSYEHLSAPLELTVWVPKLPLKVELSDNRLSFIKGWRVP----ILPDRRTARDSD------DDDDDD----RKVSRGCTLQYQRAQIKVLTQFHTTSSEGTNQMITMLGPDWQVDVTELVQDSLKVVDGRVAELADRTVLVANELGSSTLKVESPLAVEAVLGETQFSVVDEKVSIVELRVHAISGLALNLQPSPGNSHTMVAKATGLQTLSTLKQEASFSIWVYYSDNTAAPLSMYDPKDYNLNGTSADDKVVTVAQQPQQRWPVIIAEGEGTGDIVHVEMTISETCQKTK-----------RKSVIASSSVFVKVRFGTDEDSEEDMEMETEIDTRMPANTRRPAIDSNVGGAGYEPSNEQPASVPIDYTNFPTISNPEEPTEEDEEDDEFVHSPRSMTDLEIGMYALLGVFCLAILVFLINCIVFVLKYRHKRIPP----------------------EGQANMDHSHHWVFLGN------------------------------------------GEPLRTQSDLSPQTVE---------------------------------------------------------------------------------------SPSNTLEGVQTCCHGDHHS---------------------------------------------------------------------SGSSQTSVQSQVHGRGDG------SSGGSTKDH---------GED-ASSPTSKRKRVKFTTFT-LPTEDLPYNS-IPIAN-----EEDIQWVCQDMG----FQDQEELHDYMRRIKEIA--------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JEB0-1", "uniprot_id": "X2JEB0_DROME", "id": "X2JEB0-1", "name": "", "aln": "-----MMRYCLIIALQLSLAYSVEVHFEAPDS-------GFFLKHARQP----PVTPEIANVQTSSAVPPLRQRSSYDSVLS----LDRFTVVETTQPVSIRASYGPFSTKQTVPARYIVPDTMDSQSGDYMNNATLLELQQPNMHLDISAHLVRSSVSQDAPVLRVLFHAG-ADPGGHLQRQKVCVLLHVAMGSEQPLKGRCMPEGEDGVCVAEVVVPLGWWP-----QLPAPTQDGSGQAPPKVPQRYAQVSYSVFEPPLRNPEQCEP----------------KVQIQPLTTFAQVPLLAAR--TPYRMLRADDAVTFLLPQHPLYPLSRLHVPVFLHQYPDQ----RVAAFTVRARVKAGLKILGATASTDQWSVSVEKEN-PKHTTARVTAFRKEAESSLESGGNLTSEVFEVFSWLLEVAEDTNDIVDGGKIVWSVTHVYDTPKDKDSGELVIPDDNKKRLIAKLEINKDDIQAVLPMAKIWEVMNTAVLTGRQVAQAMKVFIVSQAGKVADVTLQSSCHAEDESVIKVSSSCSSVYVDGSEQRGSSNASVIVKYGTYVGVAKFIVWMPEFPLEVYISDFRLSQIKGWKVTDDNHYLHNKQSRRRKKRSYVWGQHGTNYYNNLGADKTICRARYQQSPVEVYAKFLAVD-QNSGRTSYFISRRTGLRVTDLVQPLLRVADPKIASLKGR-ILQGKSMGRTDVQVLSPIT-GRVIGTKEIRVGSDKVNLSKLIVRVISGLQLTISPDNTIENGYLAETSVTHKLTAQYQEGLLDIDLEFTDGSKTPLRDIAVEDYFLLVESLDTEVVAFAPMLASHHPRVIAVGEGNGNLLRVTLLLSEECRQRRGTLSSSKQNKSNAAPLASALASIEVDFNNVDIVSKQEAIQNDGTVGRERKNYRQTGDLADIIVGIPLRDSSQLYEPTVQARQHRGSIQAVHKGHHGKG---LAGTGTMTTMELGMYVLLTAFCFAIIVFVISCVVYASKFRPAMIESGLDPLSAGKSNGSGGSGGFRDVRLKESTTNAHDWVWLGRSTIDRQSIVAETNTHLNPRDSRMRITSNPIVNYDNGRRVSSFDQQPKLQTHIVPASNLNKQHADHYLANERKDNALDYKPPVPPHRNVGARACLPVQPVLGTGSVKDAAPNKRHSQLYRREHLQNSDSNANSQQSTPQPNQQLPTERPHPLAQAHPHPHPHQHQRSHSHSHNFSQEPLIKAAHNKIKQQQQQQQQQQHEELHNAEKLVEYTNPHQKNAFQFDSLTPKRVTKAAASSPATPSTSAVQGKAKENHSMASSTGDAANSNGTDEIIRLPASAVSQEPTTKSSRVKRATVVGNPMFSATVDESVAPGERLGLDDLDMDYEQIMHYFDNLKESNAXVQEIIAKIREILSTFHHRYQTVATPLTSPTRQQMQLLDELVAGVATATAITAAKPTPLVLDGGEGDESADAFDAYDGALDIESRQF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : * * * * *.: .:::.: : : * : : *.*.:*.: :. * ***: .*.:. : *. :.* : .:: .: *.:*:: * . *: :***: . * ... ::: : *: . : :: * * . *:.. :* *: * :.... : . . *.. * . :** :..:.* . : *. : : **::** * . * : : * . : **::.:.* *:.:*.:.: ..** * : . .**: * * . . . :*::. :*: : *.: * :* * : : . . : :: :::* : : *:**::*:: *::***:**** ** .:**. :. * * *:: .*.: *.::*** .*. *:*.*.* *** ** * . * . :: **:*::**.: :** *** :***:*. * :::: * .. :. : . * :**:: ::* ::* :.. :.: : ::. : **:**. ::* * ::* : . * . . * : .:* **:: *:* . : * .:**.: :* .:.::.* *.: *. .: :* :: .*: **. :.: : ::*.: :** .** * * * .*.:.: * ::* .** *::::. : ::* *:: : . : :*:: . :.* *. : : : : .* * : . : . :* :*:***.** .**:**:**:*.*:*:. ::* * . . : . ::*.**:**. .: : * .: * : .* . . * .:*. :.*. *. * *:*:.. *:*.::..: . :..**:* .*** :*.. * . . :. :. .: : *: : ::: : :*::* ", "identical_positions": 212, "similar_positions": 365, "identity": "14.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120927-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9UJA3-1", "uniprot_id": "MCM8_HUMAN", "id": "Q9UJA3-1", "name": "DNA helicase MCM8", "aln": "MNGEYRGRGFGRGRFQS----WKRG---RGGGNFSG----KWREREHRPDLSKTTGKRTSEQTPQ-FLLSTKTPQSMQSTLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYDKDEIERKGSILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQAQEGLSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAFLCAACGEIQSFPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEHHDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDPIPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLTEARARLELREEATKEDAEDIVEIMKYSMLGTYSDEFGNLDFERSQHGSGMSNRSTAKRFISALNNVAERTYNNIFQFHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKVYQLQTM", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CWV1-1", "uniprot_id": "MCM8_MOUSE", "id": "Q9CWV1-1", "name": "DNA helicase MCM8", "aln": "MSGAYRGRGFGRGRFQS----WKRG---RGGGNFSG----RWRERENRVDLNEASGKHASAQASQ-PLLQ-------QSTLDQFIPYKGWKLYFSEVYSNNSPFIEKIQAFEKFFTRHIDLYDKDEIERKGSILVDFKELTKADEITNLIPDIENALRDAPEKTLACMGLAIHQVLTKDLERHAAELQAQEGLSNGGETMVNVPHIYARVYNYEPLTHLKNIRATCYGKYISIRGTVVRVSNIKPLCTNMAFQCAACGEIQSFPLPDGKYTLPTKCPVPACRGRSFAPLRSSPLTVTLDWQLIKIQELMSDAQREAGRIPRTIECELVHDLVDSCVPGDTVTVTGIVKVSNSEEGSRNKNDKCMFLLYIEANSVSNSKGPKAQTAEDGCKHGTLMEFSLKDLYAIREIQAEENLLKLVVNSLCPVIFGHELVKAGLTLALFGGSQKYADDKNRIPIRGDPHVLIVGDPGLGKSQMLQAACNVAPRGVYVCGNTTTSSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKARTVSENLKMGSALLSRFDLVFILLDTPNEQHDHLLSEHVIAIRAGKQKAVSSATVTRVLSQDSNTSVLEVVSEKPLSERLKVAPGEQTDPIPHQLLRKYIGYARQYVHPRLSTDAAQALQDFYLELRKQSQRVGSSPITTRQLESLIRLTEARARLELREEATREDAEDIIEIMKHSMLGTYSDEFGNLDFERSQHGSGMSNRSTAKRFISALNSIAERTYNNIFQYHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKIYQLQTM", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F643-1", "uniprot_id": "E7F643_DANRE", "id": "E7F643-1", "name": "DNA helicase MCM8", "aln": "MSSQGSSRGSWRGGNSSGSGGWRGGGGWRGGRGWSNGQYRGWRGRQWSGGGGGGRGNYSNNNTQKGNAPQVSQARVTQATLDITCPYKGWRLYFSEGFVESSPYVEKIKVFEQYFTSQIDLYDKDEIERKGSILVDYKDLLSNKQVSHSLPDLARDLKEMPEKILDCLGVAIHQVLTLDLERHAAELQGQEELPAGIRPIINIPHISARLYNYEPLTPLKSLRANLYGKFVVIRGTVVRVSNIKPLCMKLAFVCNSCGDTQSVTLPDGKYTMPTKCLQSECRGRSFTPNRSSPFTLTVDWQTIKVQELMSGDQRESGRIPRTIECELTQDLVDSCVPGDMVTITGVIKVSNEEGSTRNKKDKCMFLLYIQANSVSNSKGQKSKAVSESEGQGPSVEFSIKDLYAIQEIQAQEDLFKLIVNSLCPVIYGHLLVKAGLALALFGGCQKYVDDKNRIPIRGDPHMLIVGDPGLGKSQMLQAVCNVAPRGVYVCGNTTTTSGLTVSLSRDSGSGDYALEAGALVLGDQGICCIDEFDKMGSQHQALLEAMEQQSISLAKAGIVCTLPARTSIIAAANPVGGHYNKGKTVSENLKMGSALLSRFDLVFILLDTPNEDHDHLLSEHVMAMRAGKSGAVSGAAATRFNTHESSISILEVSSEKPLADTLKLVPGEAFDPIPHQLLRKYVGYARHYVHPTLSAEAAQVLQDFYLELRKQNQTADSTPITTRQLESLIRLTEARARVELREKATQSDAEDVVEIMKHSLTDTYSDEFGRLDFDRSQLGSGMSNRSKVKKFVSALNKLAERTSKSMFELQDLRQLAKDLQIQVVDFEGFICALNEQGYLLKKGHRMYQLQTI", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. .** ** .* *: * *** .:*. ** *: . . *: :. :: : . *:*** *****:***** : :.** :***:.**::** :******************:*:* . :::: :**: *:: *** * *:*:******* **********.** *. . ..::*:*** **:******* **.:**. ***:: :************** ::** * :**: **..******::**** . ******:. ****:*:*:*** **:*****. ***:***********.:********** **:**::**** * .:***:*********:***:***** *::: .:. :* :***:******:****:*:*:**:********:** ******:******.***.*************:*:**************.****************:*****:**:**.***:*************** ********.********************:**:********************.:****************************.*********:*:****. ::*.*:.:*. :::*. *:*** *****:: **:.*** ***********:****:**:* **::**:.***********.* .*:*******************:****:**:.****::****:*: .*******.***:*** ********..*:*:****.:**** :.:*: ::***:**:*:***.***.** :**:******** ::*****:", "identical_positions": 569, "similar_positions": 178, "identity": "66.78%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120927-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZZ44-1", "uniprot_id": "D3ZZ44_RAT", "id": "D3ZZ44-1", "name": "", "aln": "MAGH-----GWG----APWVLVAAATLLHACGLAQGDCWLIEGDKGFVWLAICSQNQPPYEAIPQQINNTIVDLRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLSKLEYLYLQANLIEVVMASAFWECPNIVNIDLSMNRIQQLGSGTFAGLTKLSVCEIYSNPFYCSCELLGFLRWLAAFTNATQTHDRVQCESPPVYAGYFLLGQG-RHGHQRSILSKLQSVCTEGSYTAEVLGPPRPVPGRSQPGHSPPPPPP-EPSDMPCADDECFSGDGTTPLVVLTTLVPQTEARPSMKVKQLTQNSATIMVQLPSPFNRMYTLEQYNNSKSFTVSKLTQPQEEIRLTNLYTLTNYTYCVVSTSSGTHHNHTCLTICLPKPPSPPGPVPSPSTATHYIMTILGCLFGMVLVLGAVYYCLRKRRRQEEKHKKAV-AAAAGSLKKTIIELKYGPEIEAPGLAPLTQGPLLGPEAVTRIPYLPAATSDVEQYKLVESGETPKATKGNYIEVRTGEPPERRGCELSRPAPETQSSVAEISTIAKEVDRVNQIINNCIDALKSESTSFQGAKSGAVSAAEPQLVLLSEPLASKHSFLSPVYKDAFGHGGLQRHHSVEAATGPPRASTSSSGSARSPRTFRAETAGAHKAPATETKYIEKSSPVPETILTVTPAATVLRAEADKSRQYGEHRHSYPGSHPAEPPAPP--PPPPTHEGLGGRKASILEPLTRPRPRDLVYSQLSPQYHNLSYSSSPEYTCRASPSIWERLRLSRRRHKDDAEFMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQHKS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8C8T7-1", "uniprot_id": "ELFN1_MOUSE", "id": "Q8C8T7-1", "name": "Protein ELFN1", "aln": "MAGH-----GWG----TAWVLVAAATLLHAGGLAQGDCWLIEGDKGFVWLAICSQNQPPYEAIPQQINNTIVDLRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLSKLEYLYLQANLIEVVMASAFWECPNIVNIDLSMNRIQQLGSGTFAGLTKLSVCEIYSNPFYCSCELLGFLRWLAAFTNATQTHDRVQCESPPVYAGYFLLGQG-RHGHQRSILSKLQSVCTEGSYTAEVLGPPRPVPGRSQPGHSPPPPPP-EPSDMPCADDECFSGDGTTPLVILTTLVPQTEARPSMKVKQLTQNSATIMVQLPSPFNRMYTLEQYNNSKSFTVSKLTQPQEEIRLTNLYTLTNYTYCVVSTSSGTHHNHTCLTICLPKPPSPPGPVPSPSTATHYIMTILGCLFGMVLVLGAVYYCLRKRRRQEEKHKKAV-AAAAGSLKKTIIELKYGPEIEAPGLAPLTQGPLLGPEAVTRIPYLPAATSDVEQYKLVESSETPKATKGNYIEVRTGEPQERRGCELSRPG-EPQSSVAEISTIAKEVDRVNQIINNCIDALKSESTSFQGAKSGAVSAAEPQLVLLSEPLASKHSFLSPVYKDAFGHGGLQRHHSVEAAPGPPRASTSSSGSARSPRTFRAEATGTHKAPATETKYIEKSSPVPETILTVTPAATVLRAEADKSRQYGEHRHSYPGSHPAEPPAPP--PPPPTHEGLGGRKASILEPLTRPRPRDLVYSQLSPQYHNLSYSSSPEYTCRASPSIWERLRLSRRRHKDDAEFMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQHKS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C7U0-1", "uniprot_id": "ELFN1_HUMAN", "id": "P0C7U0-1", "name": "Protein ELFN1", "aln": "MAGR-----GWG----ALWVCVAAATLLHAGGLARADCWLIEGDKGFVWLAICSQNQPPYEAIPQQINSTIVDLRLNENRIRSVQYASLSRFGNLTYLNLTKNEIGYIEDGAFSGQFNLQVLQLGYNRLRNLTEGMLRGLGKLEYLYLQANLIEVVMASSFWECPNIVNIDLSMNRIQQLNSGTFAGLAKLSVCELYSNPFYCSCELLGFLRWLAAFTNATQTYDRMQCESPPVYSGYYLLGQG-RRGHR-SILSKLQSVCTEDSYAAEVVGPPRPASGRSQPGRSPPPPPPPEPSDMPCADDECFSGDGTTPLVALPTLATQAEARPLIKVKQLTQNSATITVQLPSPFHRMYTLEHFNNSKASTVSRLTKAQEEIRLTNLFTLTNYTYCVVSTSAGLRHNHTCLTICLPRLPSPPGPVPSPSTATHYIMTILGCLFGMVLVLGAVYYCLRRRRRQEEKHKKAASAAAAGSLKKTIIELKYGPELEAPGLAPLSQGPLLGPEAVTRIPYLPAAG-EVEQYKLVESADTPKASKGSYMEVRTGDPPERRDCELGRPGPDSQSSVAEISTIAKEVDKVNQIINNCIDALKSESTSFQGVKSGPVSVAEPPLVLLSEPLAAKHGFLAPGYKDAFGHS-LQRHHSVEAA-GPPRASTSSSGSVRSPRAFRAEAVGVHKAAAAEAKYIEKGSPAADAILTVTPAAAVLRAEAEKGRQYGEHRHSYPGSHPAEPPAPPGPPPPPPHEGLG-RKASILEPLTRPRPRDLAYSQLSPQYHSLSYSSSPEYTCRASQSIWERFRLSRRRHKEEEEFMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQHKS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BBN8-1", "uniprot_id": "A0A8M2BBN8_DANRE", "id": "A0A8M2BBN8-1", "name": "", "aln": "MASRRASEACYGGMVKSAFFWSVAIICLTYMGGVKGDCWLIEGEKGFVWLAICSQNQPPYEAIPQHINSTIVDLRLNENKIKSIHYSALSRFTNLTYLNLTKNEINYIEDGAFSAQFNLQVLQLGFNKLRNLTEGILRGLGKLQYLYLQANLIETVTPNAFWECPNIENIDLSMNRLQVLDGSTFTSLTKLTTCELYTNPFNCSCELLGFVKWLSVFPN--RTSERMVCDSPAGVSGYSLLSQNPTNPTYRNALHMLSTVCTEDYVTPYISVPP----------DTTTFPPD----STPCGLEDCPSGTEPEEISISPTFL-DLDVKPIMKLKQVSHTNAVITVQIPYPYKKMYILVLYNNSFFTDIQNLKRQKEDIELKNLKPHTDYTYCVASIRNSLRFNHTCLTLSTG-PKNGKERVASNATATHYIMTILGCLFSMVIVLGIVYYCLRKKRQQDEKHKKAG------SLKKNIIELKYGGELEGGTISRMSQKQMMAGESMTRMPYLPSGS-EMEQYKLQDISDTPKMAKGNYMEVRTGEHPDRRDCEMSMAG-NSQGSVAEISTIAKEVDKVNQIINNCIDALKSESTSFQGVKSGAVSTAEPQLVLISEQPQSKSGFLSPVYKDSYHHS-LQRHHASDAS--PKRPSTATGGSIRSPRPYRSE--GSYKS---ESKYIEKTSPTGETILTITPAAAILRAEAEKIRQYSEHRHSYPDAHQIEELEGP-----------ESRKTSILEPLTRPRARDLAYSQLSPQYHNLSYSSSPEYYCKPSHSIWERFKLHRKRHKDE-EYMAAGHALRKKVQFAKDEDLHDILDYWKGVSAQQKS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.: :* : :. .* * * .:.*******:*********************:**.**********:*:*::*::**** ************.********.**********:*:*******:****.**:**********.* ..:******* ********:* *...**:.*:**:.**:*:*** ********::**:.*.* :* :*: *:**. :** **.*. . . * *.:****. :. : ** :.. ** . **. ::* ** . : .*: : :.:* :*:**:::..*.* **:* *:::** * :*** :..*.: :*:*.*.** . *:*****.* . :.******:. . *.* :**************.**:*** ******::*:*:****** ****.******* *:*. :: ::* ::. *::**:****:. ::***** : .:*** :**.*:*****: :**.**:. .. :.*.*************:*********************.***.**.*** ***:** :* .**:* ***:: *. *****: :*: * *.**::.** ****.:*:* * :*: *:***** **. ::***:****::*****:* ***.*******.:* * * **:**********.***.*********.********* *:.* *****::* *:***:: *:********************************:**", "identical_positions": 475, "similar_positions": 196, "identity": "56.35%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120927-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q63633-1", "uniprot_id": "S12A5_RAT", "id": "Q63633-1", "name": "Solute carrier family 12 member 5", "aln": "MSRRFTVTSLPPAASAASADPESRRHSVADPRRLPREDVKGDGNPKESSPFINSTDTEKGREYDGRNMALFEEEMDTSPMVSSLLSGLANYTNLPQGSKEHEEAENNEGGKKKPVQAPRMGTFMGVYLPCLQNIFGVILFLRLTWVVGIAGIMESFCMVFICCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGTIEILLAYLFPAMAIFKAEDASG--EAAAMLNNMRVYGTCVLTCMATVVFVGVKYVNKFALVFLGCVILSILAIYAGVIKSAFDPPNFPICLLGNRTLSRHGFDVCAKLAWEGNETVTTRLWGLFCSSRLLNATCDEYFTRNNVTEIQGIPGAASGLIKENLWSSYLTKGVIVERRGMPSVGLADGTPVDMDHPYVFSDMTSYFTLLVGIYFPSVTGIMAGSNRSGDLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLTACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLSFLGMSLCLALMFICSWYYALVAMLIAGLIYKYIEYRGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLVRVDQDQNVVHPQLLSLTSQLKAGKGLTIVGSVLEGTFLDNHPQAQRAEESIRRLMEAEKVKGFCQVVISSNLRDGVSHLIQSGGLGGLQHNTVLVGWPRNWRQKEDHQTWRNFIELVRETTAGHLALLVTKNVSMFPGNPERFSEGSIDVWWIVHDGGMLMLLPFLLRHHKVWRKCKMRIFTVAQMDDNSIQMKKDLTTFLYHLRITAEVEVVEMHESDISAYTYEKTLVMEQRSQILKQMHLTKNEREREIQSITDESRGSIRRKNPANTRLRLNVPEETACDN-EEKPEE---------EVQLIHDQSAPSCPSSSPSPGEEPEGEGETDPEKVHLTWTKDKSAAQKNKGPSPVSSEGIKDFFSMKPEWENLNQSNVRRMHTAVRLNEVIVNKSRDAKLVLLNMPGPPRNRNGDE--NYMEFLEVLTEQLDRVMLVRGGGREVITIYS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q91V14-1", "uniprot_id": "S12A5_MOUSE", "id": "Q91V14-1", "name": "Solute carrier family 12 member 5", "aln": "MSRRFTVTSLPPAASAASADPESRRHSVADPRRLPREDVKGDGNPKESSPFINSTDTEKGREYDGRNMALFEEEMDTSPMVSSLLSGLANYTNLPQGSREHEEAENNEGGKKKPVQAPRMGTFMGVYLPCLQNIFGVILFLRLTWVVGIAGIMESFCMVFICCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGTIEILLAYLFPAMAIFKAEDASG--EAAAMLNNMRVYGTCVLTCMATVVFVGVKYVNKFALVFLGCVILSILAIYAGVIKSAFDPPNFPICLLGNRTLSRHGFDVCAKLAWEGNETVTTRLWGLFCSSRLLNATCDEYFTRNNVTEIQGIPGAASGLIKENLWSSYLTKGVIVERRGMPSVGLADGTPVDMDHPYVFSDMTSYFTLLVGIYFPSVTGIMAGSNRSGDLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLTACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLSFLGMSLCLALMFICSWYYALVAMLIAGLIYKYIEYRGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLVRVDQDQNVVHPQLLSLTSQLKAGKGLTIVGSVLEGTFLDNHPQAQRAEESIRRLMEAEKVKGFCQVVISSNLRDGVSHLIQSGGLGGLQHNTVLVGWPRNWRQKEDHQTWRNFIELVRETTAGHLALLVTKNVSMFPGNPERFSEGSIDVWWIVHDGGMLMLLPFLLRHHKVWRKCKMRIFTVAQMDDNSIQMKKDLTTFLYHLRITAEVEVVEMHESDISAYTYEKTLVMEQRSQILKQMHLTKNEREREIQSITDESRGSIRRKNPANPRLRLNVPEETACDN-EEKPEE---------EVQLIHDQSAPSCPSSSPSPGEEPEGERETDP-EVHLTWTKDKSVAEKNKGPSPVSSEGIKDFFSMKPEWENLNQSNVRRMHTAVRLNEVIVNKSRDAKLVLLNMPGPPRNRNGDE--NYMEFLEVLTEQLDRVMLVRGGGREVITIYS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9H2X9-1", "uniprot_id": "S12A5_HUMAN", "id": "Q9H2X9-1", "name": "Solute carrier family 12 member 5", "aln": "MSRRFTVTSLPPAGPARSPDPESRRHSVADPRHLPGEDVKGDGNPKESSPFINSTDTEKGKEYDGKNMALFEEEMDTSPMVSSLLSGLANYTNLPQGSREHEEAENNEGGKKKPVQAPRMGTFMGVYLPCLQNIFGVILFLRLTWVVGIAGIMESFCMVFICCSCTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGLCFYLGTTFAGAMYILGTIEILLAYLFPAMAIFKAEDASG--EAAAMLNNMRVYGTCVLTCMATVVFVGVKYVNKFALVFLGCVILSILAIYAGVIKSAFDPPNFPICLLGNRTLSRHGFDVCAKLAWEGNETVTTRLWGLFCSSRFLNATCDEYFTRNNVTEIQGIPGAASGLIKENLWSSYLTKGVIVERSGMTSVGLADGTPIDMDHPYVFSDMTSYFTLLVGIYFPSVTGIMAGSNRSGDLRDAQKSIPTGTILAIATTSAVYISSVVLFGACIEGVVLRDKFGEAVNGNLVVGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLLQAISRDGIVPFLQVFGHGKANGEPTWALLLTACICEIGILIASLDEVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFRYYHWTLSFLGMSLCLALMFICSWYYALVAMLIAGLIYKYIEYRGAEKEWGDGIRGLSLSAARYALLRLEEGPPHTKNWRPQLLVLVRVDQDQNVVHPQLLSLTSQLKAGKGLTIVGSVLEGTFLENHPQAQRAEESIRRLMEAEKVKGFCQVVISSNLRDGVSHLIQSGGLGGLQHNTVLVGWPRNWRQKEDHQTWRNFIELVRETTAGHLALLVTKNVSMFPGNPERFSEGSIDVWWIVHDGGMLMLLPFLLRHHKVWRKCKMRIFTVAQMDDNSIQMKKDLTTFLYHLRITAEVEVVEMHESDISAYTYEKTLVMEQRSQILKQMHLTKNEREREIQSITDESRGSIRRKNPANTRLRLNVPEETAGDS-EEKPEE---------EVQLIHDQSAPSCPSSSPSPGEEPEGEGETDPEKVHLTWTKDKSVAEKNKGPSPVSSEGIKDFFSMKPEWENLNQSNVRRMHTAVRLNEVIVKKSRDAKLVLLNMPGPPRNRNGDE--NYMEFLEVLTEHLDRVMLVRGGGREVITIYS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58JWE2-1", "uniprot_id": "A0AC58JWE2_DANRE", "id": "A0AC58JWE2-1", "name": "", "aln": "MSQRFTVTTGDIQGEVN--QLFEGDEETPSTAAAAGGSGKGDGNPKESSPFINSTDPEKNQQFDGKNMALFEDEMDTIPMVSSLLSSLANYSNLPQGSKEHEEAENNEGSRKKPVQAPRMGTLMGVYLPCLQNILGVILFLRMTWMVGIGGVIEAFIIVLMCCSTTMLTAISMSAIATNGVVPAGGSYYMISRSLGPEFGGAVGICFYLGTTYAGAMYILGCIEILLVYIVPQAAIFKMEGLEGAEAEAAMLNNMRVYGTLVLSFMAIVVFVGVKYVNKLALVFLACVICSILAVYAGVIKTAFEPPVFPVCVLGNRTLVWKGFDVCAKVIERENATVTTKLWRLFCDSEFLNATCDTYFTNNNVTEMQGIPGVMSGTLRENLFGNYMDKGAFIEKTGLSSVVEPDSIPTNTNR-YVLADITSFFTMLVGIYFPSVTGIMAGSNRSGDLRDAQKSIPIGTILAITTTSIIYMSSVVLFGACIEGTVLRDKFGEAVRGNLVIGTLAWPSPWVIVIGSFFSTCGAGLQSLTGAPRLMQAIARDGIVPFLRVFGHGKANGEPTWALLLTACICESGILIASLDNVAPILSMFFLMCYMFVNLACAVQTLLRTPNWRPRFKFYHWTLSFLGMSLCLSLMFICSWYYAIVAMGIAGCIYKYIEFRGAEKEWGDGIRGLSLSAARFALMRLEEGPPHTKNWRPQILVLVNMDGELKVDQPRMLSLTSQLKAGKGLTIVGTALEGTYLENHDQGQQAEQSLRKLMETEKVKGFSQVVISSNMRDAMSHLVQASGLGGLQHNTVLASWPRNWKQAEDHQSWRNFIELVRETTAGSKALLVPKNISAFPSNGERFTEGHIDVWWIVHDGGMLMLLPFLLRQHKVWRKCKMRIFTVAQMDDNSIQMKKDLTTFLYHLRIDAAVEVVEMHDSDISAYTYEKTLMMEQRSQILKQINLTKTEREREIQSITDSSRGSIRRKNPAAVTTQLSVTEEPAASSKEQKPEEECVPVSPSQQEQLIHDKSTN---PPTPATPQSPSADAQTPGTAVQMTWSEVKCDGEQNKPVGATTPEAIKDLFNMKPEWENLNQSNVRRMHTALRLNEVIIKKSQEAKLVLLNMPGPPRNRSGDE--NYMEFMEVLTEGLNRVLLVRGGGREVITIYS", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0B4LGD3-1", "uniprot_id": "A0A0B4LGD3_DROME", "id": "A0A0B4LGD3-1", "name": "", "aln": "----MQSNSAKDDSDEMEIIPSEHNGTVHETKNEDSGDIHRAEENQKS-----SIDP---------NLYLYDDDLETRPHISTFISSIANYENTIPAAT--------DPDAKPAAPSARMGTLIGVFLPCIQNIFGVILFIRLTWVVGTAGAVCGFLIVLTCCCVTMLTAISMSAIATNGVVPAGGSYFMISRSLGPEFGGAVGMLFYTGTTLAAAMYIVGAVEIVLTYMAPWASIFG--DFTK--DADAMYNNFRVYGTLLLIFMGLIVFLGVKFVNKFATVALACVILSIIAVYVGIFDNIHGNEKLYMCVLGKRLLKDIPLENCTKED--------SFLRDIYCP----DGKCEEYYLANNVTKVKGIKGLASGVFYDNIFPSFLEKGQFIS-YGKSAIDIENTSGESYNQ--IMADITTSFTLLIGIFFPSVTGIMAGSNRSGDLADAQKSIPIGTICAILTTSTVYLSSVMFFAGTVDNLLLRDKFGQSIGGKLVVANIAWPNQWVILIGSFLSTLGAGLQSLTGAPRLLQAIARDEIIPFLAPFAKSSKRGEPTRALLLTIVICQCGILLGNVDLLAPLLSMFFLMCYGFVNLACAVQTLLRTPNWRPRFKFYHWSLSLIGLTLCISVMIMTSWYFALIAMGMAIIIYKYIEYRGAEKEWGDGIRGMALTAARYSLLRLEEGPPHTKNWRPQILVLSKLNDNLLPKYRKIFSFATQLKAGKGLTICVSVIKGDHTKITNKAVDAKATLRKYMTDEKVKGFCDVLVAQQIGEGLSSVIQTIGLGGMKPNTVIIGWPYSWRQ-EGRNSWKTFIQTVRTVAACHMALMVPKGINFYPESNHKIG-GNIDIWWIVHDGGLLMLLPFLLKQHRTWRNCKLRIFTVAQIEDNSIQMKKDLKTFLYHLRIEADVEVVEMNNSDISAYTYERTLMMEQRNQMLRALGLNKKENSKVVQTIMD------YKETPSDNKMSLVQTIVDHHYD-------------------ATKTASKVRFADPTIEETQHHDSQNDEKRNSIDLDGPENADTPETTSNKDESTEKADGDFKSS----VKPDEFNVRRMHTAIKLNEVIVEKSQDAQLVIMNLPGPPREVRAERERNYMEFLEVLTEGLEKVLMVRGGGREVITIYS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: . . . .. . : : ::* * *. *: *::::::* * :*:::*.:*** * .: : . * .. :.****::**:***:***:*****:*:**:** .* : .* :*: **. ***********************:***************: ** *** *.****:* :**:*.*: * :** . ** **:***** :* *. :**:***:***:* * *.*** **:*:*.*::.. . : :*:**:* * :: *:* : * ::* :..*: *: ****:::** * ** : :*:: .:: ** ::. * .:: : . :: :::*:*: **:*:**:***************** ******* *** ** *** :*:***::*.. ::. :******::: *:**:..:***. ***:****:** *************:***:** *:*** *.:.. .**** ***** **: ***:..:* :**:********* *********************::***:**::*::**:::*:: ***:*::** :* ******:*************::*:***::*:***************:*** .:: : :::*:::********** :.::* . . :. *: ::*: * ******.:*:::.:: :.:* ::*: ****:: ***: .** .*:* *.:::*:.**: ** .:* **:*.*.:. :* . .:: * **:********:********::*:.**:**:*******::**********.******** * ******::*********:**:****.*:*: : *.*.*..: :*:* * ::.*: * . . : * .: : ..: : :.: .: : .. . : :. *: . : :: ********::*****::**::*:**::*:*****: .:. *****:***** *::*::*************", "identical_positions": 523, "similar_positions": 315, "identity": "45.36%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120928-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AGZ6-1", "uniprot_id": "A0A8I6AGZ6_RAT", "id": "A0A8I6AGZ6-1", "name": "", "aln": "MDPRAGVCQGKWTRPGIANSFALVENLHSICRRREREANVRKIFPPKSSSSDTELEDEPFGEGLVLPRAGKLHEFLSPEEETDSTSDSTGSFHRTIQVPRQRGRWDLLESLFQSDLDSDQNGSEDEENLESFFQGKSRGKLQVQDPPSLRSGSMRRCSSLIRLPSDIPKAQTLPTSDSGPPSQHRSVCSWASSITVPQPFHMTLREARKKAQWLASPASFEQERLQAQKQGQEEAECHRQFRAQPVPAHVYLPLYQEIVERREARRRARIQ----QRKELLLSSVKPFSFLEKKEEQKEDTPQRDLAAVAQTKVPPKKATSRKIPKSILEPALGDKLQESELLRKIRIQMRAMDMLQMSSSPISASSNRA---PRTATRTQEEKLSFLQTEFAFQPRVNPEVPDYEGLYKAFQRRAAERRETRETTRNKPFLLRTANLCHTPRSCDAATAGGGRMRTQKSPQPTATPLPSSRSLSGLASFSVNTLPVHITDATRKRESAVRMSLEKKDKSD-MSIQWLEMHKKNCQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMRRRIQTRPYLFEQVTKALARKEAEQRYRDTLRQAGLEEEFVRTKSQSTEAV---------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8CB59-1", "uniprot_id": "F161B_MOUSE", "id": "Q8CB59-1", "name": "Protein FAM161B", "aln": "------------------------MTVGRTAGGPECAEWSREIFPPKSSSSDTEPEDEQFGEGLVLPRAGKLHEFLSPEEDTDSTSDSTGSFYRTPQVPKQRGRWDVLESLFQSDPDSDLNDAEDEEDLESFFQDKSRGKPQVQDPPSLRHGSMRRCSSMTSLPSDIPKARILPTSDSGPPSQHRSVCSWASSITVPQPFRMTLREARKKAQWLASPASFEQERLQAQKQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERREARRRAGIR----KRKELLLSSLKPFSFLEKKEQQKEDAPQRDSAAVAQTKVSPKKATSRKIPKSILEPALGDKLQEAELLRKIRIQMRAMDTLRMASSPVSTARNRA---PRTAARTQEEKLSFLQTEFEFQPKVNPVVPDYEGLYKAFQKRAAERRETRETTRNKPFLLRTANLSHTPRSCDAATAGGG----KKSPQPTATPLPRSRSLSGLASFSANTLPVHITDATRKRESAVRMSLEKKDKSD-MSIQWLEVHKKNCQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRSNDRKRAKEYKKELEEMKKRIQTRPYLFEQVTKALARKEAEERYRDALKQAGLEEEFVRTKSQGTEAV---------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96MY7-1", "uniprot_id": "F161B_HUMAN", "id": "Q96MY7-1", "name": "Protein FAM161B", "aln": "------------------------MTVGRPEGAPGGAEGSRQIFPPES-FADTEAGEELSGDGLVLPRASKLDEFLSPEEEIDSTSDSTGSIYQNLQELKQKGRWCLLESLFQSDPESDENLSEDEEDLESFFQDKDRGMVQVQCPQALRCGSTRRCSSLNNLPSNIPRPQTQPPSGSRPPSQHRSVSSWASSITVPRPFRMTLREARKKAEWLGSPASFEQERQRAQRQGEEEAECHRQFRAQPVPAHVYLPLYQEIMERSEARRQAGIQ----KRKELLLSSLKPFSFLEKEEQLKEAARQRDLAATAEAKISKQKAT-RRIPKSILEPALGDKLQEAELFRKIRIQMRALDMLQMASSPIASSSNRANPQPRTATRTQQEKLGFLHTNFRFQPRVNPVVPDYEGLYKAFQRRAAKRRETQEATRNKPFLLRTANLRHPQRPCDAATTGRR----QDSPQPPATPLPRSRSLSGLASLSANTLPVHITDATRKRESAVRSALEKKNKAD-ESIQWLEIHKKKSQAMSKSVTLRAKAMDPHKSLEEVFKAKLKENRNNDRKRAKEYKKELEEMKQRIQTRPYLFEQVAKDLAKKEAEQWYLDTLKQAGLEEDFVRNKGQGTRAVQEKETKIKDFPRFQETTKLSIRDPEQGLEGSLEQPASPRKVLEELSHQSPENLVSLA", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7T6U5-1", "uniprot_id": "A0A8N7T6U5_DANRE", "id": "A0A8N7T6U5-1", "name": "", "aln": "-------------------------------------MDQMTMISPTLDFSRSEEGDN----------AHVSESLLSLIEDRKKTEQSMELHLEALKVKRK-------------------------QQVENLELQHQTGLEKRVLQNSLLTTSTEWMLKTNIVQQSIS-------DHDGPDRKHHSSKMVVRNSTSNRIKAARTTGSRYLGTEIERYRKPLPQDSRKAKEEADLAECQKQFRVAPVPEHISKALYDGLMHEQERLRQEGRE----QRRDFLLTMQKPFMFLKREEKKRERLREEKASANKSVKTQPVHVR-KPIPKSVSDPRFSERLKEQDQQRQMRIHLRAQQTLKAASAPIQEQEASADKQPRSTQKSKSKMLGYLDQELSFRPKINTTVPDFDKLHQAFQQKSMETTERRDVTQCKPFQLRTSTLQPRHRSPENSKNSTD-----------KVTIKRSSSFGGLTSLSMDTLPTYITDAARKRSMAVRRSLELKDLKEQENADWMKQHRIRSQAMSKAVAMRAKAMDPHKSLKEVYQEKLKQHRLADLERIKDYQRELKEMKTRVTVRPYLFEQVSQKNAKNNAERRYRNTLEQAGLDENFVRSKGERKKGSDVDNDSADEDHHSTESETQKSTGSEEDGVTNEEEKEVHVETKEEETC----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN94-1", "uniprot_id": "Q9VN94_DROME", "id": "Q9VN94-1", "name": "", "aln": "--------------------------------MSSHYLNSCVKVPIDPCNNCPAPVYNRPKLSSLGGKKPTDQAHISQPEAETPAWSSQMGVRSLAKFYDSIPDYRDVKHLHR---------VEFYSTLESLRSTSRELRSQAATAPTVERSASVSSCSVGHGKSKKR------PSKGKKIKKRPLVLDPVPPPAILVIPGQQDRCATRPVVHTPNSSCLSDEYDQCLRDLSRLKSFKEDFAVEVADFKRSLKSFEAEFRRPKSTSSNGTQTQTNKQSQTQNRCQKTANPGQHTAERAKCRREMLRRCFSVNDLQGIALEAHSKPSKLAQPARSNYFPLSKQEEIPKIQIQSPTTSSKRSSSASSAARGR---GRRGRVRKPKPGSSVKDEKPLPPLSIYELPEEPVQRRTPSVSPLHPVSRPNLAATLRAEVSRKKVKELKNNCTYHDPRPQ----------FDWEVRKTPAWKSLSLNESHKALLSIRLATRKAEQAFQ------ERQYELHMEMMRQRVKSAPLLLEGPTFWGPEVG---KLTHTCRTEELRHSCEGSRQRRKKKSEFPVPDADTKLQQLRKVYGSEKSCSRQSQRSKRSERRPQGLTTETPSHDSGDDLCSADRAFL---------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . : . :* * : .* : . . :*.: : :: : . .. . . :: . : : : : :: . :.:* . . : :: ... : . :: : *. :: : : : . . : *..: :* .: : . . :*:::: *:. * : : . :. : : * :*: :: . . . . : : : .: . : : : .*: . .. * *:** . *.: : : :. : . : :. :: . :. .* .. : : .: . .: :. : *: : :: . .:::. . . ** : .. ", "identical_positions": 23, "similar_positions": 149, "identity": "3.37%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120928-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8CBX0-1", "uniprot_id": "TM63C_MOUSE", "id": "Q8CBX0-1", "name": "Osmosensitive cation channel TMEM63C", "aln": "--MSAFPD-------SMDQK----FHNMTVNECFQ--SRSTVLQGQPFGGIPTVLVLNIILWVFVVLLYSFLRKAAWDYGRLALLIHNDS---LTSLIYG------------------EQSEK-SSPSEVS-LEAERRDRGFSSWFFNSLTMRDRDLINKCGDDARIYITFQYHLIIFVLILCIPSLGIILPVNYIGTVL---DWNSHFGRTTIVNVST-----------------ESKFLWLHSLFAFLYFLINLAFMGHHC-------LGFVPKKSLHFTRTLMITYVPTEIQDPEIISKHFHEAYPGCVVTRVHFCYDVRNLIDLDDQRRHAMR----------GRLYYTAKAKKTGKVMIKTHPCSRLCFCKCWTCFKEVDAEQYYSELEEQLTDEFNAELN-------------RVQLKRLDLIFVTFQDARTVRRIYDDYKYIHCGRHPKQSSVTTIVKNYHWRVAHAPHPKDIIWKHLSIRRFSWWTRFIAINTFLFFLFFFLTTPAIIINTID----------IYNVTRPIEKLQSPIVTQFFPSVLLWAFTVTMPLLVYLSAFLEAHWTRSSQNLIIVHKCYIFLVFMVVILPSMGLTSLHVFLRWLFDIYYLEHATIRFQCVFLPDNGAFFINYVITAALLGTGMELMRLGSLCTYCTRLFLSKSEPERVHIRKNQATDFQFGREYAWMLNVFSVVMAYSITCPIIVPFGLLYLCMKHITDRYNMYYSYAPTKLN----AQIHMAAVYQAIFAPLLGLFWML-FFSILRVGSLHSITLFSMSSLIISVVIAFSGVFLGKLR--IAQRYEQPEEETETVF-DVEPSSTTSTPTSLLYVATVLQEPELNLTPASSPARHTYGTIN-SQPEEGEEESGLRGFARELDSAQFQEGLEMEGQSH--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "D3ZNF5-1", "uniprot_id": "TM63C_RAT", "id": "D3ZNF5-1", "name": "Osmosensitive cation channel TMEM63C", "aln": "--MTASPE-------SMGQK----FRNMTANECFQ--SRSTVLQGQPFGGIPTVLLLNIILWVCVVLVYSFLRKAAWDYGRLALLIHNDS---LTSLIYG------------------EQSEK-SSPSEVY-LEAERRDKGFSTWFFNSLTMRDRDLINKCGEDARIYIMFQYHLIIFVLILCIPSLGIILPVNYIGSAL---DWSSHFGRTTIVNVST-----------------ESQFLWLHSIFAFMYFLTNFAFMGHHC-------LGFVPKKNLHFTRTLMITYVPTEIQDPETISKHFHEAYPGCVVTRVHFCYDVRNLIDLDDQRRHAMR----------GRLYYTAKAKKTGKVMIKVHPCSHLCFCKCWTCFKEVDAEQYYSELEEQLTDEFNAELN-------------RVQLKRLDLIFVTFQDARTVKRIHNDYKYINCGRHPMQSSVTTIVKNNHWRVARAPHPKDIIWKHLSIRRFSWWARFIAINTSLFFLFFFLTTPAIIINTID----------MYNVTRPIEKLQSPVVTQFFPSVLLWAFTVIMPLLVYFSAFLEAHWTRSNQNLIIMYKCYIFLVFMVVILPSMGLTSLDVFLRWLFDIYYLEHATIRFQCVFLPDNGAFFINYVITSALFGTGMELMRLGSLCTYCTRLFLSRSEPERVHIRKNLAMDFQFGREYAWMLNVFSVVMAYSITCPIIVPFGLLYLCMKHITDRYNMYYSYAPTKLN----AQIHMAAVYQAIFAPLLGLFWML-FFSILRVGSLHSITLFSLSSIIISVIIAFSGVFLGKFR--IAQQYEQPEEETETVF-DVEPSSTTSTPTSLLYVATVLQEPELNLTPASSPARHTYGTMN-SQPEEGEEESGLRGFARELDPAQFQEGLELEGQSH--", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9P1W3-1", "uniprot_id": "TM63C_HUMAN", "id": "Q9P1W3-1", "name": "Osmosensitive cation channel TMEM63C", "aln": "--MSASPDD-----LSTGGR----LQNMTVDECFQ--SRNTVLQGQPFGGVPTVLCLNIALWVLVLVVYSFLRKAAWDYGRLALLIHNDS---LTSLIYG------------------EQSEK-TSPSETS-LEMERRDKGFCSWFFNSITMKDEDLINKCGDDARIYIVFQYHLIIFVLIICIPSLGIILPINYTGSVL---DWSSHFARTTIVNVST-----------------ESKLLWLHSLLSFFYFITNFMFMAHHC-------LGFAPRNSQKVTRTLMITYVPKDIEDPELIIKHFHEAYPGSVVTRVHFCYDVRNLIDLDDQRRHAMR----------GRLFYTAKAKKTGKVMIRIHPCARLCFCKCWTCFKEVDAEQYYSELEEQLTDEFNAELN-------------RVPLKRLDLIFVTFQDSRMAKRVRKDYKYVQCGVQPQQSSVTTIVKSYYWRVTMAPHPKDIIWKHLSVRRFFWWARFIAINTFLFFLFFFLTTPAIIMNTID----------MYNVTRPIEKLQNPIVTQFFPSVMLWGFTVILPLIVYFSAFLEAHWTRSSQNLVMVHKCYIFLVFMVVILPSMGLTSLDVFLRWLFDIYYLEQASIRFQCVFLPDNGAFFVNYVITAALLGTGMELLRLGSLFCYSTRLFFSRSEPERVNIRKNQAIDFQFGREYAWMMNVFSVVMAYSITCPIIVPFGLLYLCMKHLTDRYNMYYSFAPTKLN----EQIHMAAVSQAIFAPLLGLFWML-FFSILRLGSLHAITIFSLSTLLIAMVIAFVGIFLGKLR--MVADYEPEEEEIQTVF-DMEPSSTSSTPTSLLYVATVLQEPELNLTPASSPARHTYGTMN-NQPEEGEEESGLRGFARELDSAQFQEGLELEGQNQYH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "X1WEM4-1", "uniprot_id": "TM63C_DANRE", "id": "X1WEM4-1", "name": "Osmosensitive cation channel TMEM63C", "aln": "MAFESWPAGGVRPVEELDVRSFLMEENSTAERCYRSHSRSSVLQGLPFGGVPTVLAINVVLWLILLLIFSCLRKAAWDYGRLALLMKNDS---LTSLFYG------------------EQSEKEKTPSDSSPSDSETKDMGFCSWLTSLYHMKDEEIRSKCGIDAVTYLSFQRHIILLMMVVCLLSLTIILPVNLSGNLLG--DNPENFGRTTVVNVPA-----------------QNIFLWLHSIFALLYFVITVLCMAHHS-------SRLEYREDEKVARTLMITSIPREISDPGLITKHLHEAYPSCTVTDIHFCFNVQKLMKLDSERRKAMK----------GRLYFTTKAQKNGRIMIKTHPCAQIFCCDICG-FEKVDAEQYYSELEEKLTDEFNAEKN-------------WISMKRLGIAFVTFRDERMTAVIVKDYSRARCRHKPQQSSITTVVRSHQWDVSYAPAPNDIIWENLSVCGPRWWLRCILLNILLFLLLFFLTTPAIIVNTMD----------KFNVTRPVESLRNPVITQFFPTLLLWAFSILLPFIVYYSSFFEYHWTRSGENQVTMHKCFLLLVFMVIILPSLGLSSLNLFFRWLFDVRFLDETDVKFQCVFLPDNGAFFVNYVITSSLIGTAMELLRIPALLVYSLRLCFAKSKAECIHVKISQAYEFQFGLEYAWTMCIFSVSMTYSITCPVIVPFGLLYLVLKHMVDRYNIYYAYTPTKLN----QRIHAAAISQVVVAPILCMFWLL-FFSVLRLGPVQPITLFTFITLLCSIAFSCFGFCMKKLRADRSTSYQMSDQTTEGGFSDAERSTISTTATANLFIASVLLEPELGLTPMPSPAHQSYGTMVNSQSSVRDAEEDEEKDLEETLETELKDDLLMDSPVAFQ", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q6NP91-1", "uniprot_id": "TM63_DROME", "id": "Q6NP91-1", "name": "Mechanosensitive cation channel Tmem63", "aln": "----------------MVMS-----ENSNISYCQAVANRTSFFT-TAYNGIPETLILNTIFWVLLILLFTVLRHQAGDFGRLALVNSNGSKKRWTEIFYSRAASVVDPQPSTSTQVSPRPSTTSQGVPDSTPLSPIQPEEGLFGWIRVTLKLRKETILLHTGPDAVHYLSFQQHLMAVMALVTIVSLVIILPVNFLNGPKENPYDVNAFGRTTMANLSP-----------------DSPWLWVHTIITILYIPLVVLIMRRAS-------GRNAFKK--AATRTIMISNISSSDRNKTVVRNYMQELFPDVTIENVSIAYNISRLYVRNAEFERVHE----------ARLYCEHHRNRD-TLMVKPEMCS----------CKKENAYEYYQREERKLSGDVARLRA-------------STMNEPLDIAFITVSTVQEAQNIVTHFTPG---------------TYRQWHLVFAPSPDDLFWENLNVNKSHWYLKFFCVNAVLFLVLFFLSTPAMVVSLLN----------SRPWVKETEGKISPLVADFLPTLMLWTLSALMPVIVAISDKWMRHYTRSKQNYSIMTKCFGYLLMMIMILPSLGLTSAQALLEWGFLN-----QTDRWQCIFLPDRGSFYVNYIITAAFIGTALELLRFPELIVYIWSLLKAKSKAETPYIRKAILIEFPFGTHYAWTTLVFTIAIVYSVACPLIMPFAMIYICLKHFVDRHNLYFAYGPSNMISRKGGKIHSTAVTMTKFSVVILVLVMA-MICFFRGD--NGMARFLLLIISLAITLTLFTFMSPIKR----------------CAATRRPSIVEIAGPAPIYVPDVLKDNGIRTSSVRPSAAAFGGYGSDSVSEYDSSQYSVNSVEA--------------------", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q06538-1", "uniprot_id": "CSC1_YEAST", "id": "Q06538-1", "name": "Calcium permeable stress-gated cation channel 1", "aln": "-------------MTSYIER-----LKSAASYLDTVPDEHHDFRKPTAKVVTTQLTIATSLGIFALLSFSILLK---KWPRLYASRRYKD--------------------------------------DGNLRLPSWNQSSLFGWLTVLYKIRDEQILEYAGLDAYVFLSFFKMCIKLLSIFCFFSVCVISPVRYHFTGKIDDGNDDDDSESSLIHLVKRIVEGSGDGDNHSAPERTNVYLWMYVLFTYFFTFIAIKMAVAETKHVVSTRQAYLGKQNTITDRTIRLSGIPIELRDSEALKTRIEQLKIG-TVSSITICREWGPLNKLFHCRKKILKNLELKYSECPRELRTRQPYSENYHLLGNEQSGAVTHGENVPSSNNNDEDTILYSQISLGERPKMKIGYRGIFGKEVDAIEYLEQQLKFIDAEIIEARKQHYSATPTAFVTMDSVANAQMAAQAVLDPRVHYFITRLAPAPHDIKWDHVCLSRKDRLTKVYSTTVFIGLSSLFLVIPVSYLATLLNLKTLSKFWPSVGQLLKDHQWAANIVTGLLPTYLFTLLNFGIPYFYEYLTSYQGLVSYSEEEISLVSKNFFYIFVNLFLVFTLAGTASNYWAYLSDTT-----KIAYQLATSVKEFSLFYVDLIILQGIGMFPFKLLLVGSLIGFPLVKIKAKTPRQRNELYN--PPIFNFGLQLPQPILILIITLIYSVMSTKILTSGLAYFIIGFYVYKYQLIFATDHLPHS---TGKVWPLIFRRIIVGLLLFQLTMTGTLAGFEGGWVLSSCLFPLPVVTLCFLYDFEKNYLPLSK---------------------------------YIALSSIREYERDNSTVNSANEEESYAYPYAVSELEGPMLD--------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . .. : . :. * : : : :: :: * : .: ** . : : .: *: ::.. : * ** :: * : .: :. : *: :* *:. . ..::: :: . **:: ::: :: . :: **: :: :. . : : . :.: . .: : :. : * .: . .* .. :: . . : :: : *.. . .. : :. :: : . : ** *.*: *.:: : : . : : :** *. : : . ::: ::*: :: :. :* : : * :: : * : :.. :.:: ::. :: . . : : . *::: :* .: ::*: . * : ::: : : * ** . . :: : : **: .. *:. .: *: : . . :::: :: :: . .. :: : : :. :. . * : : .. : : : :. .. .. . ", "identical_positions": 43, "similar_positions": 222, "identity": "4.72%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120928-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0M2A2-1", "uniprot_id": "A0ABK0M2A2_RAT", "id": "A0ABK0M2A2-1", "name": "non-specific serine/threonine protein kinase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWEKSGTDGSLTTTTTSATPQLHTRLTPAAIGIANATPIPGDLLRENTDEVFPDEQLSDGENGIPAGVSPDKLPGSLGHP-RPQEKDVWEEMDINKNKIKLGICKAATEEENSHGQVNGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTDKFLETCMEKMQKDSSAGKEPVLPALPHKPCVPAVPRTDHVWHYDEEYPPDASKPASANTPEQADGGGSHGFIAVNLSSCKQEVDSKEWVIVDKEQDLRDFRTNEVLG----HKTTGSPSD---EEPEVLQVLEGSPQDEKIQVGPWTDNQHLKKESSGVILALSAECPATAASELYTDRLDLQAGAASQFITVTPTSPMEAQAEGPLTAITIPRPSVAS--TQSTSGSFHYGPQPEKKDLQPLEPTVELFSP---RENFSGLAVTEGELGSGGSRVDLGLQIDHIGHGMLPNMKDGDASQDLGPRDLPDSNRLVVKEFENLPGETEEKSILLGSDNEDEKLNKGQHCIEIS-LPGDLVTTERDQSATTEPLDVSKTQNFSVVPNQDKNHEIMKLL-AVGTSEMSPQAIDPHAEGQIGQVATVQKHKLFKDD-TKSESLPGQQGDLATFLHQEGKREKVAPRNGELYHCVSESEHGPPTRKDMLRSSLVTRHSRIPVLAQEIDSTFESSSAVSAKEKLLQKKAYQPEIVKLLVEKRQFKSFLGDLSSASEKLMEEKLAAAAVPFS--EEEVFAPFSRLAVDPQLSRSVEDGFLSPIVSQSRKSKIPRPVSWVSTDQINSSASPQFLPRPPPGKPPVRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGSQKSRSTTQCKSPGSPHNPKTPPKSPVVPRRSPSASPRSSS-LPRTSSSSPSRAGRPHHDQRSSSPHLGRSKSPPSHSGSSSSRRSCQQEHCKPSKNGPKGSGSLHHHSASSKTPPGKSKPASKLSR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q3UVR3-1", "uniprot_id": "TTBK2_MOUSE", "id": "Q3UVR3-1", "name": "Tau-tubulin kinase 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MSGGGEQPDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWEKSGTDGSLTTTTTSATPQLHTRLTPAAIGIANATPIPGDLLRENTDEVFPDEQLSDGENGIPVGVSPDKLPGSLGHP-RPQEKDVWEEMDINKNKIKLGICKAATEEENSHGQVNGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIHSFELEKRLTLEPKPDTDKFLETCMEKMQKDSSAGKEPVPPALPHKPCVPVVTHTDHIWHYDDEYLPDASKPASANTPEQADGGGSNGFIAVNLSSCKQEVDSKEWVIVDKEQDLQDFRTNEVLG----HKTTGSPSD---EEPEVLQVLEGSPQDEKIQVGPWTDNHHLKKESSGVVLALSAECPATAASELYTDRLDLQAGAASQFITVTPTSPMEAQAEGPLTAITIPRPSVAS--TQSTSGSFHYGPQPEKKDLQPLEPTVELYSP---RENFSGLVVTEGELASGGSRVDLGLQIDHTGHDMLPNMRDGDTSQDLGPKDPPDHNRLAVKEFEHLPGETEERSLLLGSENEDERLSKGQHCIEVS-SPGELVTAERAQLAATEPLHVSETQNCSVLPNQDKTHEIMKLL-AVGTSEISPQAIDPHAEGQIGQMAAMQKNKLFKDDGIQSESLPRQQGDLSAFLHQEGKREKVVPRNGELYHCVSENEHGPPTRKDMLRSSFVTRHSRIPVLAQEIDSTFESSSAISAKEKLLQKKAYQPEIVKLLVEKRQFKSFLGDLSSASDKLIEEKLAAVPVPFS--EEEVFAPFSRLAADSHLSRSVEDSFLSPIISQARKSKIPRPVSWVSTDQINGSASPQFLPRPPPGKPPVRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGSQKSRSTTQCKSPGSPHNPKTPPKSPVVPRRSPSASPRSSS-LPRTSSSSPSRAGRPHHDQRSSSPHLGRSKSPPSHSGSSSSRRSCQQEHCKPSKNGPKGSGSLHHHSTSSKTPPGKSKPASKLSR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6IQ55-1", "uniprot_id": "TTBK2_HUMAN", "id": "Q6IQ55-1", "name": "Tau-tubulin kinase 2", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MSGGGEQLDILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQGKDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGRQILESIESIHSVGFLHRDIKPSNFAMGRFPSTCRKCYMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSIFLDHISSLDYFTKPDYQLLTSVFDNSIKTFGVIESDPFDWEKTGNDGSLTTTTTSTTPQLHTRLTPAAIGIANATPIPGDLLRENTDEVFPDEQLSDGENGIPVGVSPDKLPGSLGHP-RPQEKDVWEEMDANKNKIKLGICKAATEEENSHGQANGLLNAPSLGSPIRVRSEITQPDRDIPLVRKLRSIHSFELEKRLTLEPKPDTDKFLETCLEKMQKDTSAGKESILPALLHKPCVPAVSRTDHIWHYDEEYLPDASKPASANTPEQADGGGSNGFIAVNLSSCKQEIDSKEWVIVDKEQDLQDFRTNEAVG----HKTTGSPSD---EEPEVLQVLEASPQDEKLQLGPWAENDHLKKETSGVVLALSAEGPPTAASEQYTDRLELQPGAASQFIAATPTSLMEAQAEGPLTAITIPRPSVAS--TQSTSGSFHCGQQPEKKDLQPMEPTVELYSP---RENFSGLVVTEGEPPSGGSRTDLGLQIDHIGHDMLPNIRESNKSQDLGPKELPDHNRLVVREFENLPGETEEKSILLESDNEDEKLSRGQHCIEISSLPGDLVIVEKDHSATTEPLDVTKTQTFSVVPNQDKNNEIMKLL-TVGTSEISSRDIDPHVEGQIGQVAEMQKNKISKDDDIMSEDLPGHQGDLSTFLHQEGKREKITPRNGELFHCVSENEHGAPTRKDMVRSSFVTRHSRIPVLAQEIDSTLESSSPVSAKEKLLQKKAYQPDLVKLLVEKRQFKSFLGDLSSASDKLLEEKLATVPAPFC--EEEVLTPFSRLTVDSHLSRSAEDSFLSPIISQSRKSKIPRPVSWVNTDQVNSSTSSQFFPRPPPGKPPTRPGVEARLRRYKVLGSSNSDSDLFSRLAQILQNGSQKPRSTTQCKSPGSPHNPKTPPKSPVVPRRSPSASPRSSS-LPRTSSSSPSRAGRPHHDQRSSSPHLGRSKSPPSHSGSSSSRRSCQQEHCKPSKNGLKGSGSLHHHSASTKTPQGKSKPASKLSR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FE66-1", "uniprot_id": "E7FE66_DANRE", "id": "E7FE66-1", "name": "non-specific serine/threonine protein kinase", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------------------MSGGLEQIDILSTGILVKERWKILKKIGGGGFGEIYEALDLMTRTSVALKAESAQQPKQVLKMEVAVLKKLQGKDHVCRFVGCGRNDRFNYVVMELQGRNLADLRRSMNRGTFTVSTTLRLGLQILEAIESIHSVGFLHRDIKPSNFAMGRFPSTCRTCYMLDFGLARQFTNSCQEVRPPRPVAGFRGTVRYASINAHKNKEMGRHDDLWSLFYMLVEFLVGQLPWRKIKDKEQVGKLKETYDHRLMLKHLPPQFTVFLDHISNLDYFTKPDYQLLRTVFENSMRTYNVVENDPYDWERISSDSPMTITATANTPQHHTRLTPAQMGIINNSLVPGDLLKENTEEVLQDEHLSDGDN-----PRPENLLGSPKLPLRNQEIDVWEDLDRNRNRISPAVLKIGTDDEHSNQGNQSPHAGPSIGSPVRVRSELVPSDRDTPLLRKLRNIHSFELEKRLTLEPKPNTERFVEACSGKQP--PGTAQERCADGVPG-MAISNGSPTERVWHYDEEFRSGSPKPASPGSPEQGDGAANSGF--VHLSSGLQDVELRDWVMIEKVSDLQDFKESAGSSPGHVAKLTNSPSEECEEEPEVLQPMDESPD----------------KESTPSAVQADIHMSHTVLSPQRMDRLELSVFPGSGGPPVTPTSPGEALAEGALTQLPTSPASQPEELVARTCSPLHLRSPSPHTLLTTLSDPLHQRAPPGMRRSQSADYQNHPSSYTSSCHGSLPLPSQPRAAHSPGRRKLPAIPATAANTKFPSVIRITRAQLQQLTAQRPS-AMSSQCASDCGSLERRDTDNGNNGMHPQDNTADINSPQEQAAFQLTNLVNVEVDPLLNGNGHQKPSS-PVPSLIPSPRTPPSPRSPILMNGCHTPPSDTRRNGNEQLQVLKDLNSDSLTLEHVNDPTLEEGKEN-----APATNGHSSPASTPKQDPS--RRHSRIPVFE---PSSILDPPHGSAKEKLLQRRVHH-----FPLSPSASPSLSSDRRAIMIAMQRDQISSASSERSQDDESLMGSRSDRHGDDALSLSSSS---SPLL---RKSKIPRPVTPTSSMET---LTGQFMPRPPPGKPPSRSNVDGRLRRYRIRAGSTSDSDLLTCLAQLMHASSTHG---SPQHSSSSPQHVSARHIFHHLHQRSSSASPRSSSSLQRSVSSSPSR-----HEHRGG--CLGRSRSPPSFSGSPPQRRSHPHAQDG---CCARQARSITIHTQRGKAAVRCS---SKLSR", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IMC6-1", "uniprot_id": "ASATR_DROME", "id": "Q8IMC6-1", "name": "Tau-tubulin kinase homolog Asator", "aln": "MFWHLLCVPNDENASAPDDGNQSCQPSSKQDQYLSPNRNCQKNLLRLYPPPPSKPPPLVGAILQTRLLHQISPSAIADADADLNAVGELLYPNVLQRSATLPAKHNRLGVRSRVTFKVPSSNLPAQDSYSHQPRNQVAVAAKDGILVDVKAKESVKMTSEDLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTTGTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWEKVDSTAIGNISATGNP----------------SIPIKSDYMHGNITQMTVAASNASGTEYIRKRAEIETAHITATDP-----LNIKEKVDKNCNATSLAQPAKGSGEPMVQHG-NAANNQNITSKGLQQQSTLTNSQVAIANIQSAPSMIEREDVQYTKLEEGAPTKFITMKPNGECDNVDIAAK--CIFEQKHVEANDDIVGRASLSGVEQHYKSQIKKHNSPEIAN-------------------KQIQRTGTVTNDKTSEVNRSTEEQKSTFGRLRVLTAPPMS--------------------------------------VHDLPSGGGHSHQVSDLSGKQDPYAATSNAAPIGINSSSTKFGSQHGQIFGLAAMPPINRR-----SATSTNLRPSSSASQRINSGSTIGGAVGNGSNTARSSVAGDHSVTQFALIDDENVSALQQVTKGGALTLASQWKSQFDDSEDTTDNEWNREHQLQPNLEQLIKLDISLPLNEAKPFPQHGVAGTGKLINPPG----EAKGRPKRYTLNITGIENYEALRISIPNCWSEPAMGNVLRKGLEPPAVQQAAFDDTVYRMDIARNVCVRETYSEITHLARPSTSSVLRNRLPSPFKKD--------SALQLNSTNDSLDKSRHRNSLPNVSVNDIFDDLQMKLNLDLGSAIQENNCCISG-------------RLEIRVIPKDTSHPDDSVYYDAMGAVKNTPT-------ANEGHDHSDQAVNNCDEMEATSAVIAFPNKSIS--------------------KIMSPPGRDATEERTGASLCSLYSAGVNKLKLNGNTAPRTQFKKGSTDGFGENESEFDFPLLNPSKIPVRQSKCASWAGADFISAS---KPLES---------AEVPQEIPYHPQSDTTYSVIDSIPVRKTTYSIALECPPNISDLTPGLSYFYCNIVVPLRLFSILLTES-", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . *:*. * :******:::***********:. *::** .****.***:*******************:*****:*************:***:***:***: **:*::******* ***::*******************::**:* .** :*********:*.. :** **..***************:*:******************: *************** ** ****::*****.::. **:**..* * :*** :* :*:..:: .* *.**:***: .. . . ::*. . : .* :: * :: :.* : :. : * :: *.:* * * . . .: : : :. .. :: :* :. .: . ::. .: . * : .** . *. : : :.: . : ::.: . * *. .: :::: * :* .::. . * .* . . * .: . : ..:* . .* : :. . :. . : . . .: . *. . . . : . . .. ::: : . : . .: : .:.:: . .. . * .. :: * . . : . : . . . . . * . . .: . . :: :. : * : : :.:. . * :. . . *.:: .** .***: . . . . * . .. . : : :: .* . . . . : . ..*. *:* :. .* : :* :. * .* . *:: : .: . .. . * ", "identical_positions": 252, "similar_positions": 273, "identity": "17.83%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-120928-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R0W1-1", "uniprot_id": "CIPC_MOUSE", "id": "Q8R0W1-1", "name": "CLOCK-interacting pacemaker", "aln": "MRLLTRRAGHGAATLALRVIHMQRVPVLRLPAILDMERKIPSRESPRRLSAKPGRGTEMKKLARPLGVVAADSDKDSGFSDGSSECLSSAEQMESEDMLSALGCKREDKRRQPSKAADTALPTLPPMVVMKSVLVKQ-GSSSSQLQSWTVQPSFEVISAQPQLFVLHPP---VPSPVSSCQTGEKKSESRNYLPILNSYTKIAPHPGKRGLNS--EDRGTSGVSKKLCTERPGPSLSSSEPAKTGRVLSSPSTPAPPSSKLTEDSTLQGVPSLGAGGSPQTLQPVSSSHVAKAPSLTLASPASPVCASDSTLHGLESSSPLSPLSASYTSPLWAAEHLCRSPDIFSEQRQNKHRRFQNTLVVLHKSGLLEITLKTKELIRQNQATQAELDQLKEQTQMFIEATKSRAPQAWAKLQASLTSGSSHSGSDLDTLS----DHPDV----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9C0C6-1", "uniprot_id": "CIPC_HUMAN", "id": "Q9C0C6-1", "name": "CLOCK-interacting pacemaker", "aln": "-----------------------------------MERKNPSRESPRRLSAKVGKGTEMKKVARQLGMAAAESDKDSGFSDGSSECLSSAEQMESEDMLSALGWSREDRPRQNSKTAKNAFPTLSPMVVMKNVLVKQ-GSSSSQLQSWTVQPSFEVISAQPQLLFLHPP---VPSPVSPCHTGEKKSDSRNYLPILNSYTKIAPHPGKRGLSLGPEEKGTSGVQKKICTERLGPSLSSSEPTKAGAVPSSPSTPAPPSAKLAEDSALQGVPSLVAGGSPQTLQPVSSSHVAKAPSLTFASPASPVCASDSTLHGLESNSPLSPLSANYSSPLWAAEHLCRSPDIFSEQRQSKHRRFQNTLVVLHKSGLLEITLKTKELIRQNQATQVELDQLKEQTQLFIEATKSRAPQAWAKLQASLTPGSSNTGSDLEAFS----DHPAI----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7FAN7-1", "uniprot_id": "E7FAN7_DANRE", "id": "E7FAN7-1", "name": "", "aln": "------------------------------------------------------MGNKRK--------ASSDTDKDS---DASSGYFSALDQTDIEDIGPTGSAALNMPTAPRVPFITGSHPGISPMIVMNNFVLKQPNSTAPALKPWSLNTSLDVVP-QSQLLYLQPVAKCLPSGDSTSQSFDKQKHSKKHAPLQSTFQKIAPHPAQEPTVD----QGPGAINRRSSHSHAGRHHRHRYEDKPFHNFPLKQDVSETFSGYGVDPSISSLEEIGHTVEDMHVKDSPSRLSDFQEPHTTTSPFS--LCTDSFLAAFPQKFPKTSISQ--------SSDVESIPEALSPS-SSKRKRFCNTYNILNRSGLLGITMRTKELIRQNKRSQAQLQSLQAQTDLFLEAICSRDPKVWTRLQLLLQNSGNSEEMPVDSVKGVEEDLSDVGCMV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " *.: * .::::**** *.** :*: :* : **: .: . : : * :.**:**:..::** .*::. *:.*:::.*::*:. *.**: *:* :** *..:: :*:..*::: *: .:: ******.:. :*...:.:: . .: * *. . . : . : *.::..: .: . :: .* . * :** * .:** * .: .. * :.:* :..: *: :* . ..*::** ** :*::**** **::********: :*.:*:.*: **::*:** ** *:.*::** * ... :::.. * . : ", "identical_positions": 94, "similar_positions": 142, "identity": "21.08%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121001-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P61315-1", "uniprot_id": "G3ST3_MOUSE", "id": "P61315-1", "name": "Galactose-3-O-sulfotransferase 3", "aln": "MPPILQRLQQSTKMMSHRKILLLVLGCSTVSLLIHQGSQLSWYPKLFPLSCPPLRESPPRA------KHMAVAFLKTHKTAGTTVQNILFRFAERHNLTVALPHPSCEHQFCYPRNFSAHFVHPATRPPHMLASHLRFDRAELERLMPPDTIYVTILREPAAMFESLFSYYNQYCPAFRRVPNASLETFLRAPEAYYRPGEHFAMFAHNTLAYDLGGDNERSPRDDAAYLAGLIRQVEEVFSLVMIAEYFDESLVLLRRLLAWDLDDVLYAKLNARAASSRLATIPEALARAARTWNALDAGLYDHFNATFWRRVARAGRACVEREARELREARQRLLRRCFG-DEPVLRPAAQIRTKQLQPWQPSRKVDIMGYDLPS----GGAGPTTEACLKLAMPEVQYSNYLLRKQ----KRRGGVRSRPESVLDNPPPRPIRALPRIPQGT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96A11-1", "uniprot_id": "G3ST3_HUMAN", "id": "Q96A11-1", "name": "Galactose-3-O-sulfotransferase 3", "aln": "MPPILQRLQQATKMMSRRKILLLVLGCSTVSLLIHQGAQLSWYPKLFPLSCPPLRNSPPRP------KHMTVAFLKTHKTAGTTVQNILFRFAERHNLTVALPHPSCEHQFCYPRNFSAHFVHPATRPPHVLASHLRFDRAELERLMPPSTVYVTILREPAAMFESLFSYYNQYCPAFRRVPNASLEAFLRAPEAYYRAGEHFAMFAHNTLAYDLGGDNERSPRDDAAYLAGLIRQVEEVFSLVMIAEYFDESLVLLRRLLAWDLDDVLYAKLNARAASSRLAAIPAALARAARTWNALDAGLYDHFNATFWRHVARAGRACVEREARELREARQRLLRRCFG-DEPLLRPAAQIRTKQLQPWQPSRKVDIMGYDLPG----GGAGPATEACLKLAMPEVQYSNYLLRKQ----KRRGGARARPEPVLDNPPPRPIRVLPRGPQGP", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "E7F380-1", "uniprot_id": "E7F380_DANRE", "id": "E7F380-1", "name": "", "aln": "--------------MSQKKIFLVLIAISTVSFLLHHGGHLNLTLETFWMGCPSTTVSVNQGSSGHSGKHTSVAFLKTHKTASSTVQNILFRFAERNNLTVALPITSCDHQFCYPRPFSVHFVHPHTSPPDIITSHLRFSRTELRHLMPNNTIYITILREPGAMFESLFSYYNQYCLSFKRVPNGSLETFLDEPWNYYRPDEKDSMYARNTLTFDLGGDKDRP--FTELYVKRFAAEMEKVFSLVMIAEYFDESLVLLRRLLAWDLDDVLYVSLNMRTADSK-SSLSSDNTEKIRDWNAIDSALYDHFNASLWRQLRALGLACVEREVQLLRQSRDRLVRSCFGGSLPPLRSAAQITNKELRPWQPSAKVTIVGYDLPVNISKKGPIPPRDECLKMIMPEVQYTKLLLRSESVRYRKRLPIRSRQQTARSVGQPRVHKESSSQSLVP", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " **::**:*:::. ****:*:*:*.:*. : * :.**. * : ** :**********.:************:******* .**:******* **.***** * **.:::*****.*:**.:*** .*:*:******.************** :*:****.***:** * ***..*: :*:*:***::*****::*. *: : ::*:*******************************..** *:*.*: :::. :. * ***:*:.*******::**:: * ******.: **::*:**:* *** . * **.**** .*:*:***** ** *:***** *. *. : ***: ******:: ***.: ::* *:* :.. . ** : . . .", "identical_positions": 235, "similar_positions": 106, "identity": "52.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121001-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZHA1-1", "uniprot_id": "D3ZHA1_RAT", "id": "D3ZHA1-1", "name": "Beta-1,4-glucuronyltransferase 1", "aln": "MQMSYAIRCAFYQLLLAALMLVAMLQLLYLSLLSGLHGQEEQEQYFEFFPPSPRS----VDQVKSQLRTALASGGVLDASGDYRVYRGLLKTTMDPND----------VILATHASVDNLLHLSGLLERWEGPLSVSVFAATREEAQLATVLAYALSSH--CPEMRARVAMHLVCPSRYEAAVPDPREPG-EFALLRS-CQEVFDKLARVAQPGINYALGTNISYPNNLLRNLAR--EEANYALVIDVDMVPSEGLWRSLREMLD-------QSNHWDGTALVVPAFEIRRARRMPMNKNELVQLYQVGEVRPFYYGLCTPCHAPTNYSRWVN--LPEES--LLRPAYVVPWRDPWEPFYVAGGKVPTFDERFRQYG-FNRISQACELHMAGFNFEVLNEGFLVHK-GFKEALKFHPQKEAENQRNKILYRQFKQELKARYPNSPHRC-----------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8BWP8-1", "uniprot_id": "B4GA1_MOUSE", "id": "Q8BWP8-1", "name": "Beta-1,4-glucuronyltransferase 1", "aln": "MQMSYAIRCAFYQLLLAALMLVAMLQLLYLSLLSGLHGQEEQEQYFEFFPPSPRS----VDQVKSQLRTALASGGVLDASGDYRVYRGLLKTTMDPND----------VILATHASVDNLLHLSGLLERWEGPLSVSVFAATKEEAQLATVLAYALSSH--CPEMRARVAMHLVCPSRYEAAVPDPREPG-EFALLRS-CQEVFDKLARVAQPGINYALGTNTSYPNNLLRNLAR--EEANYALVIDVDMVPSEGLWRGLREMLD-------QSNHWDGTALVVPAFEIRRSRRMPMNKNELVQLYQVGEVRPFYYGLCTPCHAPTNYSRWVN--LPEES--LLRPAYVVPWRDPWEPFYVAGGKVPTFDERFRQYG-FNRISQACELHVAGFNFEVLNEGFLVHK-GFKEALKFHPQKEAENQRNKILYRQFKQELKARYPNSPHRC-----------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O43505-1", "uniprot_id": "B4GA1_HUMAN", "id": "O43505-1", "name": "Beta-1,4-glucuronyltransferase 1", "aln": "MQMSYAIRCAFYQLLLAALMLVAMLQLLYLSLLSGLHGQEEQDQYFEFFPPSPRS----VDQVKAQLRTALASGGVLDASGDYRVYRGLLKTTMDPND----------VILATHASVDNLLHLSGLLERWEGPLSVSVFAATKEEAQLATVLAYALSSH--CPDMRARVAMHLVCPSRYEAAVPDPREPG-EFALLRS-CQEVFDKLARVAQPGINYALGTNVSYPNNLLRNLAR--EGANYALVIDVDMVPSEGLWRGLREMLD-------QSNQWGGTALVVPAFEIRRARRMPMNKNELVQLYQVGEVRPFYYGLCTPCQAPTNYSRWVN--LPEES--LLRPAYVVPWQDPWEPFYVAGGKVPTFDERFRQYG-FNRISQACELHVAGFDFEVLNEGFLVHK-GFKEALKFHPQKEAENQHNKILYRQFKQELKAKYPNSPRRC-----------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "L7YAI7-1", "uniprot_id": "B4GA1_DANRE", "id": "L7YAI7-1", "name": "Beta-1,4-glucuronyltransferase 1", "aln": "--MHFSKKCSVFKVVLSALLIVALLQLLYLSFLSKLHGKQQRYKYSELFGSKKNANQGEKNPRREHLRYSLSTGGIFDGSGQYRVYKNLIKSDFSTNQKPGADPRSHHLALATHTTINNLHHLESLLERWKNPISVAIFAN-GEDVKFATAIIYALSLF--CPQVQALVDFHLVCHSGEMATFPDQDREH-FVGLQEMGCPAVFAKLESHRDKYKNYAIGSNVSYPNNLLRNVARGGTDAAYILVIDIDMIPSANLHHQFVTMLM-------KREPAADEVLVLPAFEIRHIRKMPASKPELVQLYQVGEVRPFYDELCSRCQAPTNYSLWVN--LASKSSGPLEVSYTINWVDPWEPFYIGARSVPLYDESFRQYG-FNRISQACELHIAGYRFSVVSNAFLLHK-GFKVQGEFHSRKDEENRKNRILFRSFKESLKAKYPTSPRRC-----------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9W1A7-1", "uniprot_id": "Q9W1A7_DROME", "id": "Q9W1A7-1", "name": "Beta-1,4-glucuronyltransferase 1", "aln": "---------------MDGFVVPNNSASLAFDNINLSYGRWDNQLLYRIKD------------------FALLGEQYVDSSEGS------------------------LVCLATQTSVERLNSLPQVAANWQGKMSVALFAAGPEEFVVLQYFVTYMRLC--FANIRENATFHLLTPRDFDKLPRVAALPLNMRGKFDCQYPDRTLKALLKFRSLKTLQWRQRNTYPQNHMRNLARKGCQTKYVFLTDIDIVPSTNSVPQLNHFFR-------TANCTKSCAYVIPTFEIDVRATFPRSKNALVRLIRKGLARPFHEKVFIYNQYATNFSKWLS--PNTNETEVSVSHVVTNFEFLYEPFYIAVDNAPAHDERFLGYG-FTRNSQVYEMHIAGYQFYVLSPVFTGHW-GLQRKQARPAWREQQNNANRRKFDVFKSEIFVRYKNDPRLLLKAKKNQILVK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9VK55-1", "uniprot_id": "Q9VK55_DROME", "id": "Q9VK55-1", "name": "", "aln": "------------MFRISGLLSSLVVLTFVLEISCLENGTLAKLKKFVNCESKAYK-----SSNAIYKDYWVLENYVMADHGDIPCYSN--------------------VTYTTHADYTYLDNVVPLLERWRSPLSLAIYAPGTDFEPTIHSILYLLQCHPGHDLVRQLCSIHLYFDVEHLPQVVLPPETT-LREPANCSGPPPYENVVKG----NMYRSRNTLDYPVNMGRNVARRASLTHYVLASDIELYPTPGLVPDYMHFLGRQVIGIPGQQPTSPLVHVLRIFEVMANVSVPNTKPELQEMLKSGEAVPFHMDICEACHRGPNLEEWINASVVSKELNVFNVGHRSENNNNWEPIFLGTVEDPPYDERLTWEGQRDKMTQAYAMCVLDYEFHILDNAFLVHKPGIKQPGNRKEIFPQARRTNGLIDKKISREMRMMYGSRNGCVI----------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .:: : :. * . : . : :*:: * : : .*.. :*::::* : : : :: :** : ** * **:** : * : *::: *: . :: : . *: **: .* .* * .: : * . **: : : .* . *:. :. :**:::. . * .** : * : :*. : : .: * ::. * * *:: .. * :. .: * . ", "identical_positions": 42, "similar_positions": 87, "identity": "9.15%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121003-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9BX59-1", "uniprot_id": "TPSNR_HUMAN", "id": "Q9BX59-1", "name": "Tapasin-related protein", "aln": "---MGTQEGWCLLLCLALSGAAETKP----HPAEGQWRAVDVVLDCFLAKDGAHRGALAS--SEDRARASLVLKQVPVLDDGSLEDFTDFQGGTLAQDDPPIIFEASVDLVQIPQAEALLHADCSGKEVTCEISRYFLQM-TETTVKTAAWFMANMQVSGGGPSISLVMKTPR----VTKNEALWHPTLNLPLSPQGTVRTAVEFQVMTQTQSLSFLLGSSASLDCGFSMAPGLD--LISVEWRLQHKGRGQLVYSWTAGQGQ--------AVRKGATLEPAQLGMARDASLTLPGLTIQDEGTYICQITTSLYRAQQIIQLNIQASPKVRLSLANEAL----LPTLICDIAGYYPLDVVVTWTREELGG--SPAQVSGASFSSLRQSVAGTYSISS--SLTAEPGSAGATYTCQVTHISLEEPLGASTQVVP-----------PERRTALGVIFASSLFLLA-LMFLGLQRRQAPTGLGLLQAERWETTSCADTQSSHLHEDRTARVSQPS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VD31-1", "uniprot_id": "TPSNR_MOUSE", "id": "Q8VD31-1", "name": "Tapasin-related protein", "aln": "---MGLEPSWYLLLCLAVSGAAGTDPPTAPTTAERQRQPTDIILDCFLVTEDRHRGAFAS--SGDRERALLVLKQVPVLDDGSLEGITDFQGSTETKQDSPVIFEASVDLVQIPQAEALLHADCSGKAVTCEISKYFLQARQEATFEKAHWFISNMQVSRGGPSVSMVMKTLR----DAEVGAVRHPTLNLPLSAQGTVKTQVEFQVTSETQTLNHLLGSSVSLHCSFSMAPGLD--LTGVEWRLQHKGSGQLVYSWKTGQGQ--------AKRKGATLEPEELLRAGNASLTLPNLTLKDEGNYICQISTSLYQAQQIMPLNILAPPKIQLHLANKDP----LPSLVCSIAGYYPLDVGVTWIREELGG--IPAQVSGASFSSLRQSTMGTYSISS--TVMADPGPTGATYTCQVAHVSLEEPLTTSMRVLPN----------PEQRGTLGVIFASIIFLSALLLFLGLHRQQASS-----------------SRS-----TRPMRHSG--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M1QHB2-1", "uniprot_id": "A0A8M1QHB2_DANRE", "id": "A0A8M1QHB2-1", "name": "", "aln": "MQIVSDIQQNYSISCLVSSCSVMLTLLVSLSLVYG-LDGADVVLSCSLIEEGGGMGGMMGGAMFKRTPATLVFRDFVGNEGLSPELVTPYN-PPETPNPEDLIFELMLPSIQIPNADLLLHADCNEQEVVCEISRYVPRG--ADMDSLPAHFIGSIQLEGGGISLTLVLQTLHSETTQSDAQPLMQSKLNLPLSQSATLLTEVVFVVFSRVPSIVASIGGDVMLDCGFRQKESVPGQDVALEWRLQHRGNGRKILDMKAREMETEIGSDVFVDRENTSAEADLLVRDGNASLTLRTLQVSDEGTYICTVGSGDFQTQQIVQLHITQPPRITLSEEKLSFPNRTPQRLSCHCNRYYPLDVQVEWFSQAPSSEESISLSKDSSLSSHRQHSDGTFSVSSHLTLLPDKHPPGTVVTCRVSHPSLETPTNATLTVEE-----------PEPDTAF---WTISLMLLISVVFLYQALKGGVF-----------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A8I5ZRI3-1", "uniprot_id": "A0A8I5ZRI3_RAT", "id": "A0A8I5ZRI3-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------MASQSCQRGPENAHMHPKGPCCSALCFLCS----------LGSSPHGSSLGPLRKCGRRSKPVQSSPE----GSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLE--------AVRPGANVSLLGLEHG-DASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTS--SLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCG-----------LWKWKRLTTSNTGLCLRLDVRC", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : :*.. . * :. . . : * . * .: . : . *.* * . : : : : : : .. : * : : .: * *:: * : . : : . * .:. . * :*** * : : : * * * : : : *.: *.: * : * :** : : * . . .. .. : **:*::* :: . . * * * * * . * * . ::: :: * ", "identical_positions": 40, "similar_positions": 78, "identity": "7.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121003-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P0C7N9-1", "uniprot_id": "PSMG4_MOUSE", "id": "P0C7N9-1", "name": "Proteasome assembly chaperone 4", "aln": "MEESR------AAADADVSLHNFSARLWEQLVHFHVMRLTDSLFLWVG-AT-PHLRNLAVAMCSRYDPIPVCTSLFGDTSDTTSTGLAQRLARKTSKQVFVSYNLSNTDSNFTLLVENRIKEEMETFPEKF", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5JS54-1", "uniprot_id": "PSMG4_HUMAN", "id": "Q5JS54-1", "name": "Proteasome assembly chaperone 4", "aln": "MEGLV------VAAGGDVSLHNFSARLWEQLVHFHVMRLTDSLFLWVG-AT-PHLRNLAVAMCSRYDSIPVSTSLLGDTSDTTSTGLAQRLARKTNKQVFVSYNLQNTDSNFALLVENRIKEEMEAFPEKF", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QNS5-1", "uniprot_id": "A0A2R8QNS5_DANRE", "id": "A0A2R8QNS5-1", "name": "", "aln": "MEAVLNGDCSSHASADSISLHDFSEKFLEQRVYFHLMKLSGGFFLWVGTATNPLISNLAVSILSRTDSAPLSTLVLGDTSDTTASALAQRLTKKTKKQVFVSYNLPVTDSNLLLLVENRIKQEMELHPDKF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "** *: .:***:** :: ** *:**:*:*:..:***** ** * : ****:: ** *. *:.* ::*******::.*****::**.********* ****: ********:*** .*:**", "identical_positions": 73, "similar_positions": 31, "identity": "55.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121004-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6GKT4-1", "uniprot_id": "A0A8I6GKT4_RAT", "id": "A0A8I6GKT4-1", "name": "FERM and PDZ domain-containing protein 4", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMTNRDGRDYFINHMTQAIPFDDPRFDSCQIIPPAPRKVEMRRDPVLGFGFVAGSEKPVVVRSVTPGGPSEGKLIPGDQIVMINDEPVSAAPRERVIDLVRSCKESILFTVIQP-----YPSPKSAFISAAKKARLKSNPVKVRFSEEVIING-----QVSETVKDNSLLFMPNVLKVYLENGQTKSFRFDCSTSIKDVILTLQEKLSIKGIEHFSLMLEQRTEGAGTKLLLLHEQETLTQVTQRPSSHKMRCLFRISFVPKDPIDLLRRDPVAFEYLYVQSCNDVVQERFGPELKYDIALRLAALQMYIATVTTKQT-QKISLKYIEKEWGLETFLPSAVLQSMKEKNIKKALSHLVKANQNLVPPG-KKLSALQAKVHYLKFLSDLRLYGGRVFKATLVQAEKRSEVTLLVGPRYGISHVINTKTNLVA-LLADFSHVNRIEMFTEEESLVRVELHVLDVKPITLLMESSDAMNLACLTAGYYRLLVDSRRSIFNMANKKNAGTQDTGTENKGKHNLLGPDWNCMPQMTTFIGEGEQEAQITYIDSKQKAVEMTDSTLCPKEHRHLYIDNTYSSDELSQPLTQPGDAPCEADYRSLAQRSLLTLSGPDTLKKAQESPRGAKVSFIFGDLALDDGMSPPTLGYERMLDENPEMLEKQRNLYISSANDMKNLDLTPDTDSIQFVANSVYANIGDVKNFEAPEGIEEPLLHDICYAENTDDAEDEDEVSCEED--LVVSEINQPA--ILDLSGSSDDIIDLTTLPPP-EGDDNED-DFLLRSLNMAIAAPPPGFRDSSDEEDTQSQATSFHENKEQGSSLQNEEIPVSLIDAVPTSAEGKCEKGLDPTVVSTLEALEALS--EEQQK--SENS-GVAILRAYSPESSSDSGNETNSSEMTE-GSELAAAQKQSESLSRMFLATHEGYHPLAEEQTEFPTSKTPSVGLPPKSSHGLAARPATDLPPKVVPSKQILHSDHMEMEPETMETKSVTDYFSKLHMGSVAYSCTSKRKSKLAEGEGKCPLSGNVPGKKQQGTKIAETEEDTKGKVGTVSSRDNPHLSTFNLERT--AFRKDSQRWYVASDGGVVEKSGVEAPAMKAFPRGPGLGNREAEGKEDGTMEGEADDASGLGQGERFLSDMACVASAKDLDNPEDTDSPTCDHATKLPEAEDNVARLCDYHLAKRMSSLQSEGHFSLQSSQGSSVDTGCGPGSSSSACATPVESPLCPSMGKHLIPDASGKGGSYISPEERVAGHPNHGATFKELHPQTEGMCPRMTVPALHTAINADPLFGTLRDGCHRLPKIKETTALTEPGKERQGGMPSAWSPHPEADPILLPSNIHLESKVPSPNQDPNDFSQGNQAFGEAVSWRPADLRGGSLRTPPSQRALRHSSSILSGPVGLETFQEGTKGVVSLKYPGITEAQEASSERRAELPLGKKLTKSFSQSSMHFISEGKFHKRSPMSHKDSKVYRTLPLRKLESSNWRCRGPFSYCFLNQGQDEDGDEDEEGEATLQVSCLYRPHITQGMPETSNSSLAVGLQKQGEELSRGTVLKDWTEDPDGPDDLDFSSLAFDARIARINALKANTYGMPDGFLEAQNDANELLCLVRATKAKREESRPEAYDLTLSQYKQLLSIESRQLGSACRKMAMAEKSPEEMLLAMSSSFQVLCCLTEACMRLVKVVNSETQRQEIVEKIDEVVINYICLLKAAEAATGKTTGDPSIGLSMRHSTTMAALVSTLTRSLKMLLNK", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A2AFR3-1", "uniprot_id": "FRPD4_MOUSE", "id": "A2AFR3-1", "name": "FERM and PDZ domain-containing protein 4", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MDVFSFVKIPKLS------------------------------------SHRTKSSGWPPPS-GTWGLNQVPPYGWEMMTNRDGRDYFINHMTQAIPFDDPRFDSCQIIPPAPRKVEMRRDPVLGFGFVAGSEKPVVVRSVTPGGPSEGKLIPGDQIVMINDEAVSAAPRERVIDLVRSCKESILLTVIQP-----YPSPKSAFISAAKKARLKSNPVKVRFSEEVIING-----QVSETVKDNSLLFMPNVLKVYLENGQTKSFRFDCSTSIKDVILTLQEKLSIKGIEHFSLMLEQRIEGAGTKLLLLHEQETLTQVTQRPSSHKMRCLFRISFVPKDPIDLLRRDPVAFEYLYVQSCNDVVQERFGPELKYDIALRLAALQMYIATVTTKQT-QKISLKYIEKEWGLETFLPSAVLQSMKEKNIKKALSHLVKANQNLVPPG-KKLSALQAKVHYLKFLSDLRLYGGRVFKATLVQAEKRSEVTLLVGPRYGISHVINTKTNLVA-LLADFSHVNRIEMFTEEESLVRVELHVLDVKPITLLMESSDAMNLACLTAGYYRLLVDSRRSIFNMANKKNAGTQDTGSENKGKHNLLGPDWNCMPQMTTFIGEGEQEAQITYIDSKQKTVEMTDSTLCPKEHRHLYIDNSYSSDELNQPLTQPGDAPCEADYRSLAQRSLLTLSGPDTLKKAQESPRGAKVSFIFGDLALDDGMSPPTIGYERMLEENPEMLEKQRNLYISSANDMKNLDLTPDTDSIQFVANSVYANIGDVKNFEAPEGIEEPLLHDICYAENTDDAEDEDEVSCEED--LVVGEMNQPA--ILDLSGSSDDIIDLTTLPPP-EGDDNED-DFLLRSLNMAIAAPPPGFRDSSDEEDTQSQATSFHEDKEQGSSLQNEEIPVSLIDAVPTSAEGKCEKGLDPAVVSTLEALEALS--EEQQK--SENS-GVAILRAYSPESSSDSGNETNSSEMTE-GSELAAAQKQSESLSRMFLATHEGYHPLAEEQTEFPTSKAPSVGLPPKSSHGLAARPATDLPPKVVPSKQILHSDHMEMEPETMETKSVTDYFSKLHMGSVAYSCTSKRKSKLPEGEGKSPLSGNIPGKKQQGTKIAEIEEDTKGKAGTVSSRDNPHLSTFNLERT--AFRKDSQRWYVASDGGVVEKSGMEAPAMKVFPRGPGLGNREAEGKEDGTVEGGADDASVLGQGDRFLTDMACVASAKDLDNPEDTDSPSCDHATKLSEAEDNVARLCDYHLAKRMSSLQSEGHFSLQSSQGSSVDTGCGPGSSSSACATPVESPLCPSMGKHMIPDASGKGGRYISPEERAPGHPNHGATFEELHPQTEGMCPRMTVPALHTAINADPLFGTLRDGCHRLPKIKETTV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q14CM0-1", "uniprot_id": "FRPD4_HUMAN", "id": "Q14CM0-1", "name": "FERM and PDZ domain-containing protein 4", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MDVFSFVKIAKLS------------------------------------SHRTKSSGWPPPS-GTWGLSQVPPYGWEMTANRDGRDYFINHMTQAIPFDDPRLESCQIIPPAPRKVEMRRDPVLGFGFVAGSEKPVVVRSVTPGGPSEGKLIPGDQIVMINDEPVSAAPRERVIDLVRSCKESILLTVIQP-----YPSPKSAFISAAKKARLKSNPVKVRFSEEVIING-----QVSETVKDNSLLFMPNVLKVYLENGQTKSFRFDCSTSIKDVILTLQEKLSIKGIEHFSLMLEQRTEGAGTKLLLLHEQETLTQVTQRPSSHKMRCLFRISFVPKDPIDLLRRDPVAFEYLYVQSCNDVVQERFGPELKYDIALRLAALQMYIATVTTKQT-QKISLKYIEKEWGLETFLPSAVLQSMKEKNIKKALSHLVKANQNLVPPG-KKLSALQAKVHYLKFLSDLRLYGGRVFKATLVQAEKRSEVTLLVGPRYGISHVINTKTNLVA-LLADFSHVNRIEMFSEEESLVRVELHVLDVKPITLLMESSDAMNLACLTAGYYRLLVDSRRSIFNMANKKNTATQETGPENKGKHNLLGPDWNCIPQMTTFIGEGEQEAQITYIDSKQKTVEITDSTMCPKEHRHLYIDNAYSSDGLNQQLSQPGEAPCEADYRSLAQRSLLTLSGPETLKKAQESPRGAKVSFIFGDFALDDGISPPTLGYETLLDEGPEMLEKQRNLYIGSANDMKGLDLTPEAEGIQFVENSVYANIGDVKSFQAAEGIEEPLLHDICYAENTDDAEDEDEVSCEED--LVVGEMNQPA--ILNLSGSSDDIIDLTSLPPP-EGDDNED-DFLLRSLNMAIAAPPPGFRDSSDEEDSQSQAASFPEDKEKGSSLQNDEIPVSLIDAVPTSAEGKCEKGLDNAVVSTLGALEALSVSEEQQT--SDNS-GVAILRAYSPESSSDSGNETNSSEMTE-SSELATAQKQSENLSRMFLATHEGYHPLAEEQTEFPASKTPAGGLPPKSSHALAARPATDLPPKVVPSKQLLHSDHMEMEPETMETKSVTDYFSKLHMGSVAYSCTSKRKSKLADGEGKAPPNGNTTGKKQQGTKTAEMEEEASGKFGTVSSRDSQHLSTFNLERT--AFRKDSQRWYVATEGGMAEKSGLEAATGKTFPRASGLGAREAEGKEEGAPDGETSDGSGLGQGDRFLTDVTCASSAKDLDNPEDADSSTCDHPSKLPEADESVARLCDYHLAKRMSSLQSEGHFSLQSSQGSSVDAGCGTGSSGSACATPVESPLCPSLGKHLIPDASGKGVNYIPSEERAPGLPNHGATFKELHPQTEGMCPRMTVPALHTAINTEPLFGTLRDGCHRLPKIKETTV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58GI78-1", "uniprot_id": "A0AC58GI78_DANRE", "id": "A0AC58GI78-1", "name": "", "aln": "------------------------------------------------------------------------------------------------------------------------------------------------MDVFSFVRMPKLAGQTLNWADWSCQANRSSFTSFI-----------YALCHRTKSPCCPPPAPGGWAPAQGPPNGWEMSLSREARDCYVNHLSQSSSLEEVRVDVEKFVPPAPRKVEMRRDPVLGFGFVAGSEKPVVVRSVTPGGPSEGKLIPGDEIVMINEEPVSSAPRERVIDLVRSCKESIILTVVQP-----YPSPKSAFISAAKKAKLKSNPVKVRFAEEVIING-----QVPESVKDNSLLFMPNVLKVYLENGQTKSFKFDCNTSIKDVILTLQEKLSIKSIEHFSLMLEHKVEGSATKLMLLHEQEMLTQVTQRPGSHKMKCYFRISFLPKDPVDLLRRDAAAFDYLYVQSCKDVVQERFGSELKYDTALRLAALQMYILTLSTKHT-QKVSLKYIEKEWGLAQFLPPAVLSSMKEKNIKKALTHILKTNQNLVPPG-KKLTALQAKVHYLKYLSDLRLYGGRVFKSTLVQGEKHTEVTLLVGPRYGISHVINTKTNLVA-LLADFSHVNRIEMYTEDERNVRVELHVLDVKPITLIMESSDAMNLACLTAGYYRLLVDSRRSIFNMANNSNTAGHDT----RIKHNYQAIDWNYG------TCGGCNEPHPEYAVCGRRECDISPS-------------------EIHQAHHMHGDEKAERQSRGSHMHAQPYFNIPK--GKPQESPRSAKVSFIFGDPPLDS-VNPQNLGYHRLMEDIPEVLEEHRYLYAQQK-DYKPLEASLEVDGFQYGTHMVYG---DAKIFGTTEGIEEPLLHDICYAETTDDAEEDDDISCEEDMMMMMGEMKDKANSLLSLSESSDDIIDLTSLPPPPEGDYEEDSDDLLESLNLAIAAPPPGFRDSSDEDD--------HHDR----KMSKNDIPVSLIDSVPTQVAGGSEEVFNDAVVSTLQALEALAASEDQSHPQSDNSSGVEISRSFSPESSSDSGNETNSSEMTE-SSELAAAQKLSENSLKMFVATAEGYQTLAEEETEFRLAPS----LDDPQSSAVAN----------------LRSDHFEMEPETMETKSLTEYFSKMHR----DVMRGMAQGKVEEQDSGMKSSAEAAARQLN---IAE-SEDLVGMYSNFNGRDSQCSAPFDMESMSYAFQGSNQRLHMILNNKSEEHIYSEVAGDSAPLHADRVAQKVS-----------LEDS----------IDLNASSPAKEQYLVERARS--EHQQSKGASSEQEVTRLYEYHLSKRMSSLQSEGVHSLQSSQCSSIDAGCSTGSSS--CVTPMDSPLCTVDSVHLHTESSMKGLGYTN--------QNVDGTFLRKHHGQAGAE-------------------SGREGSQRLPKIRETTDIG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VFD3-1", "uniprot_id": "Q9VFD3_DROME", "id": "Q9VFD3-1", "name": "FERM and PDZ domain-containing protein 4", "aln": "MMLLPSGRSNSDVYPLQNAANTTATSTGGATSAGGAGGAGGVGGVCGGVGATSNPKPLLLTRTSSPQLTTLPTTNGSVVHATPTRSNGCPLTQSSGIPVTMATTATAMATATPDPSGCTEVEGTASTELSTGLANETNCGTGIYGPLLGQSHGGVIAGMTENWPEIDGHLEAIQEKLKPGWSVHVGKEGRLYYCNHMTQSAGWLPACEDWSKHEELSYGWERAIDSKGRSYYINHLNKTTTYEAPECIRWDEHPPEPRQVQLQRNASLGFGFVAGSERPVIVRFVTEGGPSIGKLQPGDQILAVNGEDVKDAPRDHVIQLVRACESQVNLLVCQPMAHCVLPGRKSTLLSAGKRAKLRSRPSRVRFAESVCVNGAPLFPPSAFSLGDICVPPMANVLKVFLENGQTKSFKYDATTTVQDVVSSLLDKLCLCCGELFSLVLEHVKSLKRNKLTLLDPQESLARIAARPGAHKLRCLFRITFVPISAAELAQRDLHALDYLYLQCCNDVNQERFAPELQPELALRLAALHMHQHALANNFAPAKLTVKLVEREFGLERFVPVSLFEGMKRKELRRLISHFLKLNAEMTGSSSKVLTQLQAKLHYLDIIASLPSYGAKCFSTNQREGVER---VLLVSPRFGLSQISSARNSVQPQPISAIEDFTHVVVNREDDVTCSVSIFMLGDRAVKFIMEDRDGCEFSLVLGGYYRLLTG---NVLNILREREPNDEDNAPGFLSQHTVLPAGWSYLLPFHTRAHSVNFLMAPPYHPLVQRGQLQQQSSIQAPSSLPYVMD-----LDLHSVMATELLEEAAKDSGLSDSSGSNYCEGRSHLGSHQLEAKNEQVLRRVQELQHLVQTSEQYLSEQEQGGGGGGVAMLEFDSDCDSLNSSKVSSTEGSQGGTILGPGAIIPPGHPLKHSDSLTLLAETINHELSGITQGLNAIPESAPVSTSAPPTPATPKRKPSLCSTSSPRPQRKLNGFSQLLSDLQALGTDFSQSESDSESVASPAQSPTTRRPQ--------MMLLQAAGSSAGSVAPAKQQLSQRSSFGLHSPDGTHFGAETKDYNLREYLQQLKEISNAAS-ADTDVAARQLSEIYGFEVREDTFIETDTDLIDLRAIPPPQTPDELDSLSLMNAAPPKGFEGKAEELDSFLQQIMVAPPTQKATP-------AKELTPEEIMSFIIPPPPNLEQQQVVAPVETECLYSNSVQAKREFFQSVANGNNGTVSHSPHIIEYATVERKSKFSCCPTSKKEEQPGQEELQPPPRTPTTEQLSPPPARPPKSAELLQRYSPKKQVRIAASPVMQPQERRELCPPQLPPRGSPTLDGSQ---SSPTNAVSGPKKPPLPPIACRPRPSNGVNSPNSSSPGSAPPAHYSPPIPATVRLPHLNQANGTLPLLPKKPQQLHGEKLFIKNGHLIDGEALLAKTDVAMSGLLIKLDQVAAQCSVAQAAGGGTSIDEEKFQRARNELTEQTLALVTASKFLVASMSDMTLITLPEHLTSCLTAIRRITELAQDMTRHTSAPLQTRNIVLKVHDVASSFRELVGVEIGPIGAGQLALQAECLANVLATLLRSLRVFSP-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ..*. ::**:.:: . : . . ** **:*:::*:. **********:**:** ** **** *** ***:*: :* * *. ***::**:***:*:..: : * ** *. **:::**.*:*:*:*.* :***:*.* :** . :: * .: *.*****:*********::*..*:::**: :* :**.: * ***:**: . .** **. ** *:::: **.:**::* ***:*:* .. :* :** *::***:*.*:** ****..**: : *******:*: :::.: : *:::* :*:*:** *:* :::..**.*:::: ::*::* * ::. .. * *: ****:***. ::.* **.: *.:. :. :: .***.**:*:*:: .::..: . :: :....:: : *:: *.:.:*. :.:.::**. *. ::: : .******.. .::*: .: :. .:. :*. .*. * :: * : . . : . . . . * ..:. :* . : . :. . : . . . * . . . : * : : *.: *::. :* :. . . .. : . . .. .: .:: * . :. : : * .:* .* .* * .. .: . :* .:. . . : . *: * .: . : . : . :. * .*: **::. : . . : . :. * *. :*:. *** .* . . ::* : . .:: * ..:: . :. . . . :. :. .*: * . :. . . : : . . : : : : . . ..: : * :: . . ..** . : :: .* .: .*:..: : *.: . * * . : :. . . . : . :*:.:: : ", "identical_positions": 230, "similar_positions": 387, "identity": "11.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121004-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P49651-1", "uniprot_id": "P2RY1_RAT", "id": "P49651-1", "name": "P2Y purinoceptor 1", "aln": "MTEVPWSAVPNGTDAAFLAGLGSLWGNSTIASTAAVSSSFRCALIKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAIYVSVLVWLIVVVAISPILFYSGTGIRKNKTVTCYDSTSDEYLRSYFIYSMCTTVAMFCIPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPEMCDFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEEMTLNILSEFKQNGDTSL", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P49650-1", "uniprot_id": "P2RY1_MOUSE", "id": "P49650-1", "name": "P2Y purinoceptor 1", "aln": "MTEVPWSVVPNGTDAAFLAGLGSLWGNSTVASTAAVSSSFQCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAIYVSVLVWLIVVVAISPILFYSGTGTRKNKTVTCYDTTSNDYLRSYFIYSMCTTVAMFCIPLVLILGCYGLIVKALIYNDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPEMCDFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEEMTLNILSEFKQNGDTSL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P47900-1", "uniprot_id": "P2RY1_HUMAN", "id": "P47900-1", "name": "P2Y purinoceptor 1", "aln": "MTEVLWPAVPNGTDAAFLAGPGSSWGNSTVASTAAVSSSFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYGSILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAISPILFYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCYGLIVRALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARLDFQTPAMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKASRRSEANLQSKSEDMTLNILPEFKQNGDTSL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0N4SUG9-1", "uniprot_id": "A0A0N4SUG9_DANRE", "id": "A0A0N4SUG9-1", "name": "P2Y purinoceptor 1", "aln": "------------MTAEFNN-LTSLISN----ATDSPNQTSGCSLTKTGFQFYYLPTVYILVFLTGFIGNSLAIWMFVCHMRPWSSISVYMFNLALADFCYVLSLPFLIYYYFNKTDWIFGDVLCRLQRFIFHVNLYGSILFLTCISVHRYSGVVHPLKSLGRLKKKNAVRTVALVWFIVVAGIAPILYYSRT-SRKKEHTTCYDTTSQDELPGYFIYSMCLTVFGFCIPFIIILSCYGGIVKALICNDMDNAPLRKKSIYLVIIVLTVFAVSYLPFHVMKNLNMRARLYFQSPDMCAFNDRVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATKKSSRKGDHPLQSKSEETALNSLPESVQNGENRM", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * * .* :* : ..: *:* **********:******: **:***:****** **:***.************* ***:** **:************.:*:*********************.*******:*************: .***:***..*:***:** * **:: ****:**:: * .******* ** **:*:::**.*** **:*** :*:**:***:*****************:******.:*:**** **:* ** ******************************************:*:**:.: ******: :** *.* ***:. :", "identical_positions": 254, "similar_positions": 59, "identity": "68.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121005-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O95190-1", "uniprot_id": "OAZ2_HUMAN", "id": "O95190-1", "name": "Ornithine decarboxylase antizyme 2", "aln": "MINTQDSSILPLSNCPQLQCCRHIVPGPLWCSDAPHPLSKIPGGRGGGRDPSLSALIYKDEKLTVTQDLPVNDGKPHIVHFQYEVTEVKVSSWDAVLSSQSLFVEIPDGLLADGSKEGLLALLEFAEEKMKVNYVFICFRKGREDRAPLLKTFSFLGFEIVRPGHPCVPSRPDVMFMVYPLDQNLSDED", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "O08608-1", "uniprot_id": "OAZ2_MOUSE", "id": "O08608-1", "name": "Ornithine decarboxylase antizyme 2", "aln": "MINTQDSSILPLSKCPQLQCCRHIVPGPLWCSDAPHPLSKIPGGRGGGRDPSLSALIYKDEKLTVTQDLPVNDGKPHIVHFQYEVTEVKVSSWDAVLSSQSLFVEIPDGLLADGSKEGLLALLEFAEEKMKVNYVFICFRKGREDRAPLLKTFSFLGFEIVRPGHPCVPSRPDVMFMVYPLDQNLSDED", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A0R4IGR0-1", "uniprot_id": "A0A0R4IGR0_DANRE", "id": "A0A0R4IGR0-1", "name": "", "aln": "MCNTEES-------CAVLGS-RQRAPGPLWCSDAPLPLTKIPGGRGTGRDLPHS-VLHKDEKLTVTEAGSVS-GAPPVLHFQYQLSERRISSWDTVLSDDALYLEIPAGALHNGSREGFTRLLEFAEEQLKVSYVFLWLHKNRDDRLSIMKTFHYMGFEVVKPGHPLVPARPDLLFMVYSMDSSSSDEE", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* **::* *. * . *: .********** **:******* *** . * :::********: .*. * * ::****:::* ::****:***.::*::*** * * :**:**: *******::**.***: ::*.*:** .::*** ::***:*:**** **:***::****.:*.. ***:", "identical_positions": 103, "similar_positions": 53, "identity": "54.5%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121005-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A0Y7-1", "uniprot_id": "D4A0Y7_RAT", "id": "D4A0Y7-1", "name": "", "aln": "MEGQTRGSRGLPEKPLPATTHPPLSSLGAVFILLKSALGAGLLNFPWAFYKAGGLVPTFLVALVSLVFLISGLVILGYAASVSGQ-TTYQGVVRELCGPAMGKLCEACFLTNLLMISVAFLRVIGDQLEKLCDSLL---PDAPQP-----WYAAQSFTLPLISVLVIFPLSALRDIALQEYTSILGTLAACYLALVITVQYYLWPQGLI---RQPGPLLSP--SPWTSVFSVFPTICFGFQCHEAAVSIYCSMQNQSLPHWTLVSVLSLMACCLVYTLTGVYGFLTFGTEVSADILMSYPGNDTAIIVARVLFAVSIVTVYPIVLFLGRSVMQ---------------------------DFWKKSYWATQGSPVLADPS-----------------------------------------------GPWVRLPLTFLWVAVTLAMALFLPDLSEIIGVIGGLS-AFFIFIFPGLCLISAVDTEPIGPRVKSRTTGSHGYHHEQFEEAGTDINRIGVVLPRRYCCVVWCEAQDCG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5HZH7-1", "uniprot_id": "S38A8_MOUSE", "id": "Q5HZH7-1", "name": "Solute carrier family 38 member 8", "aln": "MEGQPRGSRGPLEKPLPAATHPTLSSLGAVFILLKSALGAGLLNFPWAFYKAGGMLPTFLVALVSLVFLISGLVILGYAASVSGQ-TTYQGVVRELCGPAMGKLCEICFLTNLLMISVAFLRVIGDQLEKLCDSLL---PDAPQP-----WYAAQNFTLPLISMLVIFPLSALREIALQKYTSILGTLAACYLALVITVQYYLWPQGLI---RQPGPLLSP--SPWTSVFSVFPTICFGFQCHEAAVSIYCSMWNQSLSHWTLVSVLSLLACCLVYTLTGVYGFLTFGPEVSADILMSYPGNDTAIIVARVLFAVSIVTVYPIVLFLGRSVMQ---------------------------DFWKKSYWATRGPPVLADPS-----------------------------------------------GPWVRLPLTFLWVVVTLTMALFLPDLSEIISIIGGVS-SFFIFIFPGLCLICAVDTEPMGPRVKC-----------CLEAWGILSVLVGTFIFGQSTAVAMVELL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NNN8-1", "uniprot_id": "S38A8_HUMAN", "id": "A6NNN8-1", "name": "Solute carrier family 38 member 8", "aln": "MEGQTPGSRGLPEKPHPATAAATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISGLVILGYAAAVSGQ-ATYQGVVRGLCGPAIGKLCEACFLLNLLMISVAFLRVIGDQLEKLCDSLLSGTPPAPQP-----WYADQRFTLPLLSVLVILPLSAPREIAFQKYTSILGTLAACYLALVITVQYYLWPQGLV---RESHPSLSP--ASWTSVFSVFPTICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYSLTGVYGFLTFGTEVSADVLMSYPGNDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQ---------------------------DFWRRSCLGGWGPSALADPS-----------------------------------------------GLWVRMPLTILWVTVTLAMALFMPDLSEIVSIIGGIS-SFFIFIFPGLCLICAMGVEPIGPRVKC-----------CLEVWGVVSVLVGTFIFGQSTAAAVWEMF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A5WVQ9-1", "uniprot_id": "A5WVQ9_DANRE", "id": "A5WVQ9-1", "name": "", "aln": "MEELAKESISFLSKSSLETNEPRLGSLGAVFIMLKSALGAGLLIFPWAFAKAGGIHFAVTVEMISLVFLISGLVILGYSSSVSGR-NTYQGVVTDICGPAIGKLCEICYVFNLFFISVAFLVIVADQLHKLCLSMYELITGLPESEMPYHWYTDQRFALFLLCLLFIFPLSVPKEISIQKYTSVLGTFAAAYLTVAIVVKYHMRPIHEI---NLS-PLYSSGISSWDSVFSVIPTICFGFQCHEACVAVYSSMENRRLSHWVFISVLSMLICLLIYSLTGVFGYLTFGKNVAPDILMSYSGGDVTMIVARLLFGISIITIYPIIVLLGRSVIQ---------------------------DPLLRRRLKH---TAVTESY-----------------------------------------------ESRTRVALTTAWVTVTLLIAVFIPDISKVISVVGGVS-AFFIFIFPGLCLIFVVQSESVSPTMRY-----------LLVTWGMITLLCGTLIFGQSTSVAIMQLITEV", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38176-1", "uniprot_id": "AVT5_YEAST", "id": "P38176-1", "name": "Vacuolar amino acid transporter 5", "aln": "---------------------MPSNVRSGVLTLLHTACGAGVLAMPFAFKPFGLMPGLITLTFCGICSLCGLLLQTRIAKYVPKSENASFAKLTQLINPSISVVFDFAIAVKCFGVGVSYLIIVGDLVPQIVQSIFYRNDDNMSGSQEHHMFLDRRLYITLIIVFVISPLCFKRSLNSLRYASMIAIVSVAYLSGLIIYHFVN-RHQLE--RGQVYFMVPHGDSQSHSPLTTLPIFVFAYTCHHNMFSVINEQVDKSFKVIRRIPIFAIVLAYFLYIIIGGTGYMTFGENIVGNILTLY-PNSISTTIGRLAMLLLVMLAFPLQCHPCRSSVKNIIIFI---------------------ENFRKGKLYDNR----ASFIPLDNFNSE---------DPQEAPTQQNNEEPN-----------LRSESLRHINIITLCILLFSYLLAISITSLAKVLAIVGATGSTSISFILPGLFGYKLIGSEFTGTNERVPTS------IKIFKYLSLSLFIWGIAVMVASLSAIVFLGTSSH", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40074-1", "uniprot_id": "AVT6_YEAST", "id": "P40074-1", "name": "Vacuolar amino acid transporter 6", "aln": "---------------------MVASIRSGVLTLLHTACGAGILAMPYAFKPFGLIPGVIMIVLCGACAMQSLFIQARVAKYVPQG-RASFSALTRLINPNLGIVFDLAIAIKCFGVGVSYMIVVGDLMPQIMS-VWTRN----------AWLLNRNVQISLIMLFFVAPLSFLKKLNSLRYASMVAISSVAYLCVLVLLHYVAPSDEILRLKGRISYLLPP-QSHDLNVLNTLPIFVFAYTCHHNMFSIINEQRSSRFEHVMKIPLIAISLALILYIAIGCAGYLTFGDNIIGNIIMLY-PQAVSSTIGRIAIVLLVMLAFPLQCHPARASIHQILQHFAE-------------------ENVSISATSADEPTVATESSPLIRDSSL---------DLNEVIEEESIYQPK-----------ETPLRGKSFIVITCSILVASYLVAISVSSLARVLAIVGATGSTSISFILPGLFGYKLIGTEHK---TAVPLT------TKIFKYTGLLLFIWGLIIMITCLTAALKLN----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40501-1", "uniprot_id": "AVT7_YEAST", "id": "P40501-1", "name": "Vacuolar amino acid transporter 7", "aln": "-------------------MEATSSALSSTANLVKTIVGAGTLAIPYSFKSDGVLVGVILTLLAAVTSGLGLFVLSKCSKTLINPRNSSFFTLCMLTYPTLAPIFDLAMIVQCFGVGLSYLVLIGDLFPGLFG--------------------GERNYWIIASAVIIIPLCLVKKLDQLKYSSILGLFALAYISILVFSHFVFELGKGELTNILRNDICWWKIHDFKGLLSTFSIIIFAFTGSMNLFPMINELKDNSMENITFVINNSISLSTALFLIVGLSGYLTFGNETLGNLMLNYDPNSIWIVIGKFCLGSMLILSFPLLFHPLRIAVNNVIIWIEITYGGANPEEDPQVSEYTRASNLRPISMTVEDPAQPSDALDATSYNEQECLLPNGNFDNGSIESQENNNDERGTMAVAGDNEHHAPFVKSRFYWITALLLISMYTLALSVQSFALVLSFVGATGSTSISFTLPGLLGYKLIGLDSLAIGKMIPPK------DRFYKRCSLLLVFYGLSVMFLSLYVTVFNRSDEA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . ... :::: *** * :*::* * : . : . . :: : : : : : * :. : : . : : :.:::: ::.* . : . : ..: **. :.: .*:*::. : .*: : :: . :..:. : *.: ..: . . : : :: . :: * *::*** : ::: * :.:. : :: :*: * :: . :. :* : :*: : .:: ::..:*. . : : * :*** : : . * : . ", "identical_positions": 31, "similar_positions": 125, "identity": "5.79%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121005-6", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D4A0Y7-1", "uniprot_id": "D4A0Y7_RAT", "id": "D4A0Y7-1", "name": "", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGQTRGSR---GLPEKPLPATTHPPLSSLGAVFILLKSALGAGLLNFPWAFYKAGGLVPTFLVALVSLVFLISGLVILGYAASVSGQ-TTYQGVVRELCGPAMGKLCEACFLTNLLMISVAFLRVIGDQLEKLCDSLL--------PDAPQPWYAAQSFTLPLISVLVIFPLSALRDIALQEYTSILGTLAACYLALVITVQYYLWPQGLIRQ-PGPLLSPSP----WTSVFSVFPTICFGFQCHEAAVSIYCSMQNQSLPHWTLVSVLSLMACCLVYTLTGVYGFLTFGTEVSADILMSYPGNDTAIIVARVLFAVSIVTVYPIVLFLGRSVMQ---------------------------DFWKKSYWATQGSPVLADPS-----------------------------------------------GPWVRLPLTFLWVAVTLAMALFLPDLSEIIGVIGGLS-AFFIFIFPGLCLISAVDTEPIGPRVKSRTTGSHGYHHEQFEEAGTDINRIGVVLPRRYCCVVWCEAQDCG", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q5HZH7-1", "uniprot_id": "S38A8_MOUSE", "id": "Q5HZH7-1", "name": "Solute carrier family 38 member 8", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGQPRGSR---GPLEKPLPAATHPTLSSLGAVFILLKSALGAGLLNFPWAFYKAGGMLPTFLVALVSLVFLISGLVILGYAASVSGQ-TTYQGVVRELCGPAMGKLCEICFLTNLLMISVAFLRVIGDQLEKLCDSLL--------PDAPQPWYAAQNFTLPLISMLVIFPLSALREIALQKYTSILGTLAACYLALVITVQYYLWPQGLIRQ-PGPLLSPSP----WTSVFSVFPTICFGFQCHEAAVSIYCSMWNQSLSHWTLVSVLSLLACCLVYTLTGVYGFLTFGPEVSADILMSYPGNDTAIIVARVLFAVSIVTVYPIVLFLGRSVMQ---------------------------DFWKKSYWATRGPPVLADPS-----------------------------------------------GPWVRLPLTFLWVVVTLTMALFLPDLSEIISIIGGVS-SFFIFIFPGLCLICAVDTEPMGPRVKC-----------CLEAWGILSVLVGTFIFGQSTAVAMVELL---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A6NNN8-1", "uniprot_id": "S38A8_HUMAN", "id": "A6NNN8-1", "name": "Solute carrier family 38 member 8", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------MEGQTPGSR---GLPEKPHPATAAATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISGLVILGYAAAVSGQ-ATYQGVVRGLCGPAIGKLCEACFLLNLLMISVAFLRVIGDQLEKLCDSLLSGT-----PPAPQPWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSILGTLAACYLALVITVQYYLWPQGLVRE-SHPSLSPAS----WTSVFSVFPTICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYSLTGVYGFLTFGTEVSADVLMSYPGNDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQ---------------------------DFWRRSCLGGWGPSALADPS-----------------------------------------------GLWVRMPLTILWVTVTLAMALFMPDLSEIVSIIGGIS-SFFIFIFPGLCLICAMGVEPIGPRVKC-----------CLEVWGVVSVLVGTFIFGQSTAAAVWEMF---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58G4J0-1", "uniprot_id": "A0AC58G4J0_DANRE", "id": "A0AC58G4J0-1", "name": "", "aln": "MSVSSLRSVSFGPYTEQMILVFPASMYAEPFAWLTSPQRANTGRTSPFPRTPCLLLGALGALSGDRKSNGDCDSSGPRIRFVSTGIFNKPTCLREHSLLCSGETTQSSSRNQMLRDAAIKCCLRAAALCRIGITWQIDGLHILPEESYLTVAFQLKTGLEALRMEELARESIRSISLLSKPARGSDVPRLGSFGAIFIMLKSALGAGLLNFPWAFEKAGGVNTAISVEMVSLVFLISGLVILGYASSISRQ-NTYHDVVRNVCGRRIGHLCEICFVFNLFMISVAFLVVVQDQLEKLCLSLYETVTGNTEAEMPHHWYTDYRFALSFMCLIIILPLSIPKEIGIQKYTSVMGTLAATYLSVAVIAKYYLKDTHTADLTPEHSQGLGS----WASMFSVVPTICFGFQCHEASIAIYSSMENKKITHWVFISVTSMIFCLLIYTLTGVFGFLTFGRKVASDILMSYPGNDVVMIIARLLFGISIVTIYPIILLLGRSVIL---------------------------TQILR-FWERR--TIMTPVF-----------------------------------------------EGRCRLILTILWITVTLLIAIFVPDMSEVISVIGGIS-AFFIFIFPGLCLIFVMQTEPINHRIRI-----------LLTGWGVVTIVIGAFIFGQSTTIAVMELAHKF", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "P38176-1", "uniprot_id": "AVT5_YEAST", "id": "P38176-1", "name": "Vacuolar amino acid transporter 5", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPSNVRSGVLTLLHTACGAGVLAMPFAFKPFGLMPGLITLTFCGICSLCGLLLQTRIAKYVPKSENASFAKLTQLINPSISVVFDFAIAVKCFGVGVSYLIIVGDLVPQIVQSIFYRNDDNMSGSQEHHMFLDRRLYITLIIVFVISPLCFKRSLNSLRYASMIAIVSVAYLSGLIIYHFVN-RHQLE--RGQVYFMVPHGDSQSHSPLTTLPIFVFAYTCHHNMFSVINEQVDKSFKVIRRIPIFAIVLAYFLYIIIGGTGYMTFGENIVGNILTLY-PNSISTTIGRLAMLLLVMLAFPLQCHPCRSSVKNIIIFI---------------------ENFRKGKLYDNR----ASFIPLDNFNSE---------DPQEAPTQQNNEEPN-----------LRSESLRHINIITLCILLFSYLLAISITSLAKVLAIVGATGSTSISFILPGLFGYKLIGSEFTGTNERVPTS------IKIFKYLSLSLFIWGIAVMVASLSAIVFLGTSSH", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40074-1", "uniprot_id": "AVT6_YEAST", "id": "P40074-1", "name": "Vacuolar amino acid transporter 6", "aln": "-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVASIRSGVLTLLHTACGAGILAMPYAFKPFGLIPGVIMIVLCGACAMQSLFIQARVAKYVPQG-RASFSALTRLINPNLGIVFDLAIAIKCFGVGVSYMIVVGDLMPQIMS-VWTRN----------AWLLNRNVQISLIMLFFVAPLSFLKKLNSLRYASMVAISSVAYLCVLVLLHYVAPSDEILRLKGRISYLLPP-QSHDLNVLNTLPIFVFAYTCHHNMFSIINEQRSSRFEHVMKIPLIAISLALILYIAIGCAGYLTFGDNIIGNIIMLY-PQAVSSTIGRIAIVLLVMLAFPLQCHPARASIHQILQHFAE-------------------ENVSISATSADEPTVATESSPLIRDSSL---------DLNEVIEEESIYQPK-----------ETPLRGKSFIVITCSILVASYLVAISVSSLARVLAIVGATGSTSISFILPGLFGYKLIGTEHK---TAVPLT------TKIFKYTGLLLFIWGLIIMITCLTAALKLN----", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P40501-1", "uniprot_id": "AVT7_YEAST", "id": "P40501-1", "name": "Vacuolar amino acid transporter 7", "aln": "-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MEATSSALSSTANLVKTIVGAGTLAIPYSFKSDGVLVGVILTLLAAVTSGLGLFVLSKCSKTLINPRNSSFFTLCMLTYPTLAPIFDLAMIVQCFGVGLSYLVLIGDLFPGLFG--------------------GERNYWIIASAVIIIPLCLVKKLDQLKYSSILGLFALAYISILVFSHFVFELGKGELTNILRNDICWWKIHDFKGLLSTFSIIIFAFTGSMNLFPMINELKDNSMENITFVINNSISLSTALFLIVGLSGYLTFGNETLGNLMLNYDPNSIWIVIGKFCLGSMLILSFPLLFHPLRIAVNNVIIWIEITYGGANPEEDPQVSEYTRASNLRPISMTVEDPAQPSDALDATSYNEQECLLPNGNFDNGSIESQENNNDERGTMAVAGDNEHHAPFVKSRFYWITALLLISMYTLALSVQSFALVLSFVGATGSTSISFTLPGLLGYKLIGLDSLAIGKMIPPK------DRFYKRCSLLLVFYGLSVMFLSLYVTVFNRSDEA", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . .. :::: *** * :*::* * : : : . . :: : : : : : :. : : .: : : :.:::: :: * . : : ..: **. :.: .*:*::. : *:. : :: . :.... : *.: ..: . . : : :: . :: * *::*** : .::: * : :.:. : :: :*: * : : :* : :*: : .:: ::..:*. . : : * :*** : : . * : ", "identical_positions": 30, "similar_positions": 121, "identity": "4.28%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121009-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O88808-1", "uniprot_id": "TUB_RAT", "id": "O88808-1", "name": "Tubby protein homolog", "aln": "--------MTSKPHSDWIPYSVLDDEGSNLRQQKLDRQRALLEQKQKKKRQEPLMVQANADGRPRSRRARQSEEQAPLVESYLSSSGSTSYQVQEADSLASVQPGATRPPAPASAKKTKGAAASGGQGGAPRKEKKGKHKGTSGPATLAEDKSEAQGPVQILTVGQS--DHAKDAGETAAGGGAQPSG-QDLRATMQRKGISSSMSFDEEE-DEDENSSSSSQLNSNTRPSSATS--RKSTREAASAPSPAAPEPPVDIEVQ-DLEEFALRPAPQGITIKCRITRDKKGMDRGMYPTYFLHLDREDGKKVFLLAGRKRKKSKTSNYLISVDPTDLSRGGDSYIGKLRSNLMGTKFTVYDNGVNPQKASSSTLESGTLRQELAAVCYETNVLGFKGPRKMSVIVPGMNMVHERVCIRPRN-EHETLLARWQNKNTESIIELQNKTPVWNDDTQSYVLNFHGRVTQASVKNFQIIHGNDPDYIVMQFGRVAEDVFTMDYNYPLCALQAFAIALSSFDSKLACE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "P50586-1", "uniprot_id": "TUB_MOUSE", "id": "P50586-1", "name": "Tubby protein", "aln": "--------MTSKPHSDWIPYSVLDDEGSNLRQQKLDRQRALLEQKQKKKRQEPLMVQANADGRPRSRRARQSEEQAPLVESYLSSSGSTSYQVQEADSIASVQLGATRPPAPASAKKSKGAAASGGQGGAPRKEKKGKHKGTSGPATLAEDKSEAQGPVQILTVGQS--DHDKDAGETAAGGGAQPSG-QDLRATMQRKGISSSMSFDEDE-DEDENSSSSSQLNSNTRPSSATS--RKSIREAASAPSPAAPEPPVDIEVQ-DLEEFALRPAPQGITIKCRITRDKKGMDRGMYPTYFLHLDREDGKKVFLLAGRKRKKSKTSNYLISVDPTDLSRGGDSYIGKLRSNLMGTKFTVYDNGVNPQKASSSTLESGTLRQELAAVCYETNVLGFKGPRKMSVIVPGMNMVHERVCIRPRN-EHETLLARWQNKNTESIIELQNKTPVWNDDTQSYVLNFHGRVTQASVKNFQIIHGNDPDYIVMQFGRVAEDVFTMDYNYPLCALQAFAIALSSFDSKLACE", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P50607-1", "uniprot_id": "TUB_HUMAN", "id": "P50607-1", "name": "Tubby protein homolog", "aln": "--------MTSKPHSDWIPYSVLDDEGRNLRQQKLDRQRALLEQKQKKKRQEPLMVQANADGRPRSRRARQSEEQAPLVESYLSSSGSTSYQVQEADSLASVQLGATRPTAPASAKRTKAAATAGGQGGAARKEKKGKHKGTSGPAALAEDKSEAQGPVQILTVGQS--DHAQDAGETAAGGGERPSG-QDLRATMQRKGISSSMSFDEDEEDEEENSSSSSQLNSNTRPSSATS--RKSVREAASAPSPTAPEQPVDVEVQ-DLEEFALRPAPQGITIKCRITRDKKGMDRGMYPTYFLHLDREDGKKVFLLAGRKRKKSKTSNYLISVDPTDLSRGGDSYIGKLRSNLMGTKFTVYDNGVNPQKASSSTLESGTLRQELAAVCYETNVLGFKGPRKMSVIVPGMNMVHERVSIRPRN-EHETLLARWQNKNTESIIELQNKTPVWNDDTQSYVLNFHGRVTQASVKNFQIIHGNDPDYIVMQFGRVAEDVFTMDYNYPLCALQAFAIALSSFDSKLACE", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PZ13-1", "uniprot_id": "A0A8M9PZ13_DANRE", "id": "A0A8M9PZ13-1", "name": "Tubby-like protein", "aln": "MTMDGLSNNKSMSYSRWSYDSTLDDEGTNLRQQKLDRQRALLEQKQKKKRQEPLMVQSNLDGRSRVRRTRQSEEQAPLVESYLSGNSSTIYHVQEAE--QEEVKAVAEVQAPRSAKKSK-PPTSTPQTGSAKKEKKGKHKGIDGPAAFQDEGQELGNQIQILTVGHSPAQESEAEGQGEAVGSTHSQGKQDLRVTMLKKGISSSMNFDEEEDEDDLVSSSSSQLNSNTRPGSATS--KKSSKEATSASTPLANEP--SIDVD-DLEEFTLRPAPQGVTVKCRITRDKKGMDRGMYPTYYLHLEREDGKKVFLLAGRKRKKSKTSNYLISIDPTDLSRGGESFIGKLRSNLMGTKFTVYDSGMNPVKTTSS-LEAGNLRQELAAICYETNVLGFKGPRKMSVIIPGMNMDHERVSIRPRN-EHESLLARWQNKSTESVIELHNKTPVWNDDTQSYVLNFHGRVTQASVKNFQIIHDNDPDYIVMQFGRVAEDVFTMDYNYPMCALQAFAIALSSFDSKLACE", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q86PC9-1", "uniprot_id": "TULP_DROME", "id": "Q86PC9-1", "name": "Protein king tubby", "aln": "------------------------MSGINSRNQKMEQQRQLMEAYIRQKRASPGMVQASDLQINRP----------------MSGMRSNSRELHAYDG---------PMQFISSPQNPDQILTNGSPGGINPVAMNTSRNHSNNMRSLSTINQEADLIEEISSHELE----DEESSPVTVIEQHQQSASHSANSTQSQKPRARQHSFSDNLDEDDYTNRNVAGAAPVRPAGMASSPYKDATLDGSSNGTGNGTGGESEGDVIGNIDQFVMQPAPQGVLYKCRITRDRKGMDRGLFPIYYLHLERDYGKKIFLLGGRKRKKSKTSNYIVSCDPTDLSRNADGFCGKLRSNVFGTSFTVFDNGNKE--------STESPRLDLAVIIYDTNILGFKGPRNMTVILPGMTEDDQRVKISSADPKQQGILDLWKMKNMDNIVELHNKTPVWNDETQSYVLNFHGRVTQASVKNFQLVHDSDPEYIVMQFGRTSEDVFTMDYRYPLCAMQAFAIALSSFDGKIACE", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* * *:**:::** *:* ::** .* ***:. * :*. *. .:: : *.:... : * : .:: .. :: .* :* : . : . . : .. :. . * :* : . .*.:: ::: . . : . .. *:* :.: :.:* : . . :* ::::*.::*****: *******:******::* *:***:*: ***:***.************::* *******..:.: ******::**.***:*.* : .: . * :**.: *:**:*******:*:**:***. .:** * . : ::: :* *: *. :.::**:********:*********************::*..**:********.:********.**:**:***********.*:***", "identical_positions": 187, "similar_positions": 141, "identity": "35.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121009-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O15240-1", "uniprot_id": "VGF_HUMAN", "id": "O15240-1", "name": "Neurosecretory protein VGF", "aln": "MKALRLSASALFC-LLLINGLGAAPPGRPEAQPPPLSSEHKEPVAGDAVPGPKDGSAPEVRGARNSEPQDEGELFQGVDPRALAAVLLQALDRPASPP-APSGSQQGPEEEAAEALLTETVRSQTHSLPAPESPEP-AAPPRPQTPENGPEASDPSEELEALAS-LLQELRDFSPSSAKRQQETAAAETETRTHTLTRVNLE----SPGPERVWRASWGEFQAR----VPERAPLPPPAPSQFQARMPDSGPLP---ETHKFGEGVSSPKTHLG-------EALAPLSKAYQGVAAPFPKARRPESALLGGSEAGERLLQQG-----LAQVEAGRRQAEATRQAAAQEERLADLASDLLLQYLLQGGARQRGLGGRGLQEAAEERESAREEEEAEQERRGG-EERVGEEDEEAAEAEAEAEEAERARQNALLFAEEEDGEAGAEDKRSQEETPGHRRKEAEGTEEGGEEEDD-EEMDPQTIDSLIELSTKLHLPADDVVSIIEEVEEKRKRKKNAPPEPVPPPRAAPAPTHVRSPQPPPPAPAPARDELPDWNEVLPPWDREEDEVYPPGPYHPFPNYIRPRTLQPPSALRRRHYHHALPPSRHYPGREAQARRAQEEAEAEERRLQEQEELENYIEHVLLRRP----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q0VGU4-1", "uniprot_id": "VGF_MOUSE", "id": "Q0VGU4-1", "name": "Neurosecretory protein VGF", "aln": "MKTFTLPASVLFCFLLLIQGLGAAPPGRPDVFPPPLSSEHNGQVAEDAVSRPKDDGVPEVRAARNPEPQDQGELFQGVDPRALASVLLQALDRPASPPSVPGGSQQGTPEEAAEALLTESVRSQTHSLPAPEIQAPAVAPPRPQTQDRDPEEDDRSEELEALAS-LLQELRDFSPSNAKRQQETAAAETETRTHTLTRVNLE----SPGPERVWRASWGEFQAR----VPERAPLPPPVPSQFQARMSESAPLP---ETHQFGEGVSSPKTHLG-------ETLTPLSKAYQSLGGPFPKVRRLEGSFLGGSEAGERLLQQG-----LAQVEAGRRQAEATRQAAAQEERLADLASDLLLQYLLQGGARQRDLGGRELQETQQERENEREEE-AEQERRGGGEDDVGEEDEEAAEAEAEAEEAERARQNALLFAEEEDGEAGAEDKRSQEEAPGHRRKDAEGAEEGGEEDDDDEEMDPQTIDSLIELSTKLHLPADDVVSIIEEVEEKRKRKKNAPPEPVPPPRAAPAPTHVRSPQPPP--PAPARDELPDWNEVLPPWDREEDEVFPPGPYHPFPNYIRPRTLQPPASSRRRHFHHALPPARHHPDLEAQARRAQEEADAEERRLQEQEELENYIEHVLLHRP----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B7N4-1", "uniprot_id": "A0ACD6B7N4_DANRE", "id": "A0ACD6B7N4-1", "name": "", "aln": "MTWCQHTSNIPIIFLFMLFSLTVKPAAFSPVTTDRNTVSENYAAASSAQQQALYTQPAEEQGTTHDENEDDDELFKDVDPRTLAAVLLGALNQKEKMSEREDEGTEGQKERDLQGADRDRDGHKELELVMAAAQGNDEKEREEEEKKRAEEEERMTEKVTSRTTSQTVPIKEQVALQEEATQEDVTKEEERQEPEGGKAEEEEEQLSPEEVKNLETMLEEFQSYSTAAKRERDTRQRESRGEYFDYLDRNGLMNNEIKPKAKGNDLALSKKKLKWQLEQEKNRVQPLQRGGNFMDDFSNNLADPEEEDEEDQEDEEQLSPEEEETRAKAEQEEVRRQAAEAQRAKAEEEKLADIASDMLLKYIVKQ-DKKKYQDNNGAEDKRSDEDTNDDDEDIDPQTIDKLIEISSKLHLPADDVVDIINDVEKKKKKDAPENLPWQHPLVPPPAPAAPSTVLRKPPPSKPPQPNTNPLKAWFKDRASVKPSKQDMWARQQWPFRTYPSYNSYQKPYRGYYPVYIPPPKPKSRYYSKPSFSLNDVLGN---SLDYDFDYSPRRKSRPWAQPRQRVQP--AFQRNLYFPHPRTFKAVPMPKPRSPPRRWPSFYYPARAPVVTREDDYYSPLRQPPQDSEEELENFIERVFMKHPRMFQ", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. .:. : *::: .* . *.. . . . : ..: .* .* . .* :.: : * :*:.***:.****:**:*** **:: . . . . :* *. :. : : .* . . : .. * . :*:: : :: ::: . . : ** .: * * : :.: * ** : .: ***: ** . .:: : .. : :.: *:.:: .*.:* : : **.:. : : : * ..* *:* : *: * **** :::* *:**:***:***:**:*::: ::: ... :: .:.:. ::* : : . : .: . * :. ::.*: ::: : . : .: :: :: .: . : . : ... * :: :: : * * . : * * * * .* . *:. . : * . .. ** : .:.* * .:: : :***::. . : * : *. : . . :*. : : .: :.:*****:**:*::::* ", "identical_positions": 100, "similar_positions": 216, "identity": "15.43%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121017-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q86UD1-1", "uniprot_id": "OAF_HUMAN", "id": "Q86UD1-1", "name": "Out at first protein homolog", "aln": "MRLPG---VPLARPALLLLLPLLAPLL---------GTGAPAELRVRVRLPDGQVTEESLQADSDADSISLELRKPDGTLVSFTADFKKDVKVFRALILGELEKGQSQFQALCFVTQLQHNEIIPSEAMAKLRQKNPRAVRQAEEVRGLEHLHMDVAVNFSQGALLSPHLHNVCAEAVDAIYTRQEDVRFWLEQGVDSSVFEALPKASEQAELPRCRQVGDHGKPCVCRYGLSLAWYPCMLKYCHSRDRPTPYKCGIRSCQKSYSFDFYVPQRQLCLWDEDPYPG", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8QZR4-1", "uniprot_id": "OAF_MOUSE", "id": "Q8QZR4-1", "name": "Out at first protein homolog", "aln": "MRPPGCRDVPSARPALPLLLLLLSPLLLGALHGVGAGSGAPAELRVRVRLPDSQVIEESLQADSDADSISLDLRKPDGTLISFIADFKKDVKIFRALILGELEKGQSQFQALCFVTRLHHNDIIPSEAMAKLRQKNPRAVRQAEEVRGLEQLHMDIAVNFSQGGLLSPHLHNVCAEATDAIYTRQEDVQFWTERGVDSSVFEALPKALEQAELPRCGRVGDRGKPCTCHYSLSLAWYPCMLKYCHSRDRPAPYKCGIRSCRKSYTFDFYVPQKQLCLWDEDP---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B6L8-1", "uniprot_id": "A0ACD6B6L8_DANRE", "id": "A0ACD6B6L8-1", "name": "Out at first protein homolog", "aln": "MN------ARVASPASVQIAFTVFTLLL--------SVSVCSRLTVLVRLGDSQIAEEILEADSVKDIITLEFKQTDGTLITFLADFKRHVKVFRALVLGEPEKGQSQYQALCIISHLDHGEFIPSEAMARLRQKNAHVVRSAEERRAVERFSLNTVVNMSLSWQLSAHIRNICRDARDLVYTRQQDVLHWMDRGIASSIFEEFPPNANVTSLQSCSSTSDPWRPCACSYSLNLEWFPCQLKYCRSQG-PNPYKCGIKSCSKGYRFDFYTPQKQLCLWDEGS---", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*. . * ** : : .** . .. :.* * *** *.*: ** *:*** * *:*::::.****::* ****:.**:****:*** ******:****::::*.*.::*******:*****.:.**.*** *.:*:: :: .**:* . **.*::*:* :* * :****:** .* ::*: **:** :* : :.* * ..* :**.* *.*.* *:** ****:*:. * ******:** *.* ****.**:*******.. ", "identical_positions": 135, "similar_positions": 80, "identity": "47.37%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121017-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NZN5-1", "uniprot_id": "ARHGC_HUMAN", "id": "Q9NZN5-1", "name": "Rho guanine nucleotide exchange factor 12", "aln": "MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERIA---SHDFDPTDSSSKKTKSSSEESRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGTLVTHSNHLEVVKLIKSGSYVALTVQGRPPGSPQIPLADSEVEP-SVIGHMSPIMTSPHSPGASGNMERITSPVLMGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTPAQRLLKEIQEAKKHIPQLQEQLSKATGSAQDGAVVTPSRPLGDTLTVSEAETDPGDVLGRTDCSSGDASRPSSDNADSPKSGPKERIYLEENPEKSE-TIQDTDTQSLVGSPSTRIAPHIIGAEDDDFGTEHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKHTNSKETRRIFLEFHQFFLDRSAHLKVSVPDEMSADLEKRRPELIPEDLHRHYIQTMQERVHPEVQRHLEDFRQKRSMGLTLAESELTKLDAERDKDRLTLEKERTCAEQIVAKIEEVLMTAQAVEEDKSSTMQYVILMYMKHLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDKEGEEKGKRRGFPSILGPPRRPSRHDNSAIGRAMELQKARHPKHLSTPSSVSPEPQDSAKLRQSGLANEGTDAGYLPANSMSSVASG--ASFSQEGGKENDTGSKQVGETSAPGDTLDG--TPRTLNTVFDFPPPPLDQVQEEECEVERVTEHGTPKPFRKFDSVAFGESQSEDEQFENDLETDPPNWQQLVSREVLLGLKPCEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQLHIGLNEQMKAVRKRNETSVIDQIGEDLLTWFSGPGEEKLKHAAATFCSNQPFALEMIKSRQKKDSRFQTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPTEREKVKKAADHCRQILNYVNQAVKEAENKQRLEDYQRRLDTSSLKLSEYPNVEELRNLDLTKRKMIHEGPLVWKVNRDKTIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVIKLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTKPIPLPQSTPGEGDNDEEDPSKLKEEQHGISVTGLQSPDRDLGLESTLISSKPQSHSLSTSGKSEVRDLFVAERQFAKEQHTDGTLKEVGEDYQIAIPDSHLPVSEERWALDALRNLGLLKQLLVQQLGLTEKSVQEDWQHFPRYRTASQGPQTDSVIQNSENIKAYHSGEGHMPFRTGTGDIATCYSPRTSTESFAPRDSVGLAPQDSQASNILVMDHMIMTPEMPTMEPEGGLDDSGEHFFDAREAHSDENPSEGDGAVNKEEKDVNLRISGNYLILDGYDPVQESSTDEEVASSLTLQPMTGIPAVESTHQQQHSPQNTHSDGAISPFTPEFLVQQRWGAMEYSCFEIQSPSSCADSQSQIMEYIHKIEADLEHLKKVEES-YTILCQRLAGSALTDKHSDKS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R4H2-1", "uniprot_id": "ARHGC_MOUSE", "id": "Q8R4H2-1", "name": "Rho guanine nucleotide exchange factor 12", "aln": "MSGTQSTITDRFPLKKPIRHGSILNRESPTDKKQKVERSS---SHDFDPTDSSSKKTKSSSEESRSEIYGLVQRCVIIQKDDNGFGLTVSGDNPVFVQSVKEDGAAMRAGVQTGDRIIKVNGTLVTHSNHLEVVKLIRSGSYVALTVQGRPPGSPQIPLADSEVEP-SVTGHMSPIMTSPHSPGAAGNMERITSPVLVGEENNVVHNQKVEILRKMLQKEQERLQLLQEDYNRTATQRLLKEIQEAKKHIPQLQEQLSKATGSAQDGAVIAPSRPLGDALTLSEAEADPGDGLCRTDWSSGDASRPSSDSADSPKSSLRERSYLEEAPERSE-GVQDAEPQSLVGSPSTRGAPHIIGAEDDDFGTEHEQINGQCSCFQSIELLKSRPAHLAVFLHHVVSQFDPATLLCYLYSDLYKQTNSKETRRVFLEFHQFFLDRSAHLKVPVPEEISVDLEKRRPELIPEDLHRLYIQTMQERVHPEVQRHLEDFRQKRSMGLTLAESELTKLDAERDKDRGTLEKERACAEQIVTKIEEVLMTAQAVEEERSSTMQYVILMYMKYLGVKVKEPRNLEHKRGRIGFLPKIKQSMKKDREGEEKGKRRGFPSILGPPRRPSRHDNSAIGRAMEIQKSRHPKHLSTPSSVSPEPQDPAKLRQSGVANEGTDTGYLPASSMSSATSG--TALSQEGGRENDTGTKQVGEASAPGDCLDS--TPRVPTTVFDFPPPLLDQVQEEECEVERVAEHGTPKPFRKFDSIAFGESQSEDEQFENDLETDPPNWQQLVSREVLLGLKPSEIKRQEVINELFYTERAHVRTLKVLDQVFYQRVSREGILSPSELRKIFSNLEDILQLHVGLNEQMKAVRKRNETSVIDHIGEDLLIWFSGPGEEKLKHAAATFCSNQPFALEMIKSRQKKDSRFHTFVQDAESNPLCRRLQLKDIIPTQMQRLTKYPLLLDNIAKYTEWPPEREKVKKAADHCRQILNYVNQAVREAENKQRLEDYQRRLDTSNLKLSEYPNVDELRNLDLTKRKMIHEGPLVWKVNRDKSIDLYTLLLEDILVLLQKQDDRLVLRCHSKILASTADSKHTFSPVIKLSTVLVRQVATDNKALFVISMSDNGAQIYELVAQTVSEKTVWQDLICRMAASVKEQSTKPIPLPQPPPCEGDNDEEEPAKLKVEHHDLSVAGLQSPDRVLGLESPLISSKPQSHSLNTPGKSAAEHLFVTATQFAKEQHANGALKEGDGGYPVTIPGPHLPVSEERWALDALRNLGLLKQLLVQQLGLTEKSTQEDWQSFSRYGPASEEVQADSGIRDLENVKACHAREGQMSFKTGTGDIATCDSPRTSTESCAAQDSVILASQDSQASNVLVMDHMILTPEMPPAEPEGGLDESGEHFFDAREAHSDDNPSEGDGAVKKEEKDVNLRISGNCLILDGYDAVQESSTDEEVASSFPLQPVTGIPAVDSSHQQQHSPQNVHPEGPVSPFTPEFLVQRHWRAMEDTCFEIQSPS-CTDSQSQILEYIHKIEADLEHLKKVEES-YALLCQRLAGSALPDKLSDKS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FDV8-1", "uniprot_id": "E7FDV8_DANRE", "id": "E7FDV8-1", "name": "", "aln": "MSDTRSTVSD--------RTSSFLSRDHPPDKRPKSDKLPGTPTHEFDPTDVLVQKSGCVVADRRPESCGLVQRCVIIQKDENGFGLTVSGDNPVFVQLVKQDGAAMRAGVQTGDRIIKVNGTLVTQSNHVEVVKLIKSGSYVALTVLGRPPGLPQIPLPEVDVGLESPDVFGDPFITSPNSYNAA---ERTSSPLVSWEENSALHNQRMDSRRTGLKDQQD--------------------------------TQESPCLRNSEDGSWAEEDQYKRDFSPEAFWSGNSVPSVHRRFYPASPESQRDS-NCSSPKSTPRDSFNSCPSPEVDYGSDLDSRFPSTVGSP--RLVSEIIAAEDDDFDSEQEQVNGQCSCFQSIQLLKTRPAHLAAFLHHVISQFDPAPLLCYLYADLYKQTNSKETRRIFTDFLTFFIDRGANLKVTVPESISSELERRRPELIPEELHRQYIQTMQETLFPDVQRNLEDFRQKRSMGLTLADTELSRLDSEQ----LAVDRERACAESILSKIDDVLLTSQPTEEEKCSTIQYVIFMYMKHLGVRAKEQRNLESKRVRINFLPSKLRKSKTEKDGEEKLKKSRFP-IRVPPRWPGRLDSVPSGRVGDSIKQRPQKQMSQPALGGSELIDAGRLRGS-QSSEGSDLLHSPGLITSSPFSAPYSSPSDPSGRDSEFNMSPSAVVPRLSDGLQSGDPLDSIYPPCDYIPYNVDQLDED-RDGDRPPDVGTPKPSRRFEDLQSEDDQGSD----VYSDVDPPNWQQLVGRDVLAGLTPHEIKRQEVINELFYTERAHVRMLKVLDKVFYQKLNRDNILPPADIKYIFTNLEEIIQLHVRIVDQMTAICKKNETSVIDHIGDELLSWFSSGEEEKIKQAVGTFCSNQPFALELIKSRQKKDQRFSSFMQEAESNRLCRRLQLKDIIPAEMQRFTKYPLLMDNIAKYTDESEEKDKVRRAAECCRQILNHVNQSVKESENKQRLEDYQRRLDLSSLKQSENPMISEFKNLDLTKRKMVHEGPLSWKINKDKTIELYTLLLEDILVLLQKQDERLILRCHSKNLAGTAETKHIFSPIIKLSTVLVRSVATDNRSFFVISMSKNGAQIYELMAQTVSEQRMWQRQITQRAEVMNTKPHSVIPLPQH---DGDRDGVELSKFSKGSDRISTGSIQSAEK----DGEFSPSAALRDCVPDTNPGEEDQVARAGRDASYQDSELLNGRETDS------------LSCSSKADEALKTLAALKQVLLTQLMAQD--------------------------------------EGERLGRSAGSRLLRTTSLRTPVEHNSNR-----------------------TPSRAQDYTSG---DTG--FYECPEDYAA------------------------YLVLEGFGGSGESSTDDDFQVGRKEPGLAHSCAADSGISLKFSSPSSGSTSRLS--------------------------------RQVLSHLRCLQANLNHLKEMETKYYNLLRQRPVGSAAEADESREKK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "**.*:**::* * .*:*.*: *.**: * :: . :*:***** :*: . : *.* ************:**************** **:************************:***:******:********* ***** *****.: :* * . .*::***:* .*: ** :**:: ***..:***::: *. *:.:*: * * . .::**: .: * . : . :. : * .:. *: .* ...**** :: ** . *: * **** * ...**.******.:*:**:**********:***:******.*****:******.******:****:********:* :* **:**.*:***.**:.:* :**:********:*** ******* :.*:***:***************::**::**:*: ::::**:***.*::**::**:*:*..**::.**:****:****:***:.** **** ** **.***. :. *.:::**** *: ** * *** *.* *. . **. : * * *::* *: ..* *..:** * :.**:* : *. ** *. :: *: .*::.: . . . .. .* *:. . . *: * :**::*: : :* .: ***** *:*:.: :.*..* :.*********.*:** **.* ******************** *****:****::.*:.**.*:::: **:***:*:***: : :**.*: *:*******:**::** ***. ***:*:*..***********:********.** :*:*:**** ************::***:******:*******: . *::**::**: ******:***:*:*:************** *.** ** * :.*::*********:***** **:*:**:*:*****************:**:****** **.**::** ***:*********.*****:::******.********:******: :** * : * :: :. . ***** :**.* : :*:. . :*. .:**.:: :. : .* . ..: .. . .: : : : :: :* . :* . * :**:.*. ***:*: ** : **. ::. . : * **..* : : **. . ..* ::* *::. * :: *:*:*:. *****::. . :: *.:* . :.*. . . . :* *::.::: ::*:*:***::* . * :* ** .*** . * :. ", "identical_positions": 684, "similar_positions": 381, "identity": "43.99%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121019-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F1M2D4-1", "uniprot_id": "F1M2D4_RAT", "id": "F1M2D4-1", "name": "", "aln": "-----------------MNGVAFCLVGIP----PRPEP--------------------------------------RPPQLP--LGSRDGCSSGRPLP--------------WQGPRTLLLHKNLQDGFGFTLRHFIVYPPE---------------------SAVHCSLKEEENGSRGGQGGQGGGRGGRGGRGGRGGRGAGGRGGGGGPSPRHRLEPMDTIFVKNVKEGGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIGLIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNE-----------------------------------------------------PYSGEARSIPEPPPLCYPRKTYAP------PTRAPAWATMVPEPISALPTDPRSPAAWS----------------------DPGSRVTSATRAHLDNSSLGMS------QPR-----------------PSPGAFPHLPSE-------------SRTPRAFL-ESGSRVLPSR-LECQQALSHWLSNQIPRRAGERR-------CPAMPPRARSASQDRLEDVTTHHP-------WPCSTSQDALSQLGQ---------------------------EGWHRARSDDYLSR----ATRSAEALG-PGALVSPRLERCGWASQRSS-------------------------------------ARTSACPSRDLPGPQAPPASGLQGLDDIGYIGYRSYSPSFQRRTG--LLHALSFRDSPFGG---LPTFSLAQSPASFPPEASEPP-------------------RVARPDPSTR-ALEPPAEDHRDEVVLRQKPPTGR---KVQLTPARQVNLG-------FGDESLEPEA--RGERPGR----KVAPLATTEDSLASIPFIDEPTSPSIDLQAKHVPASAVVSS-AMNSAP---VLGTSPSSPTFTFALSRHYSQDCSSIKAGRRSSYLLAITTERSKSCDDG-----LNTFRDEGRVLRRLPNRVPSLRMLRSFFTDGSLDSWGTSEDAEAPSKRHSTSDLS------DATFSDIRREGWLYYKQILTKKGKKAGGGLRQWKRVYAVLRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRAIRENSRAEGEDP-------GCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQT-----AVRGLRTQDQPAGSKEDSVTTPKTPWGINIIKKNKKAAP-------------------RAFGIRLEDCQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDIN--LQDERWQDLNVISSLLKAFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHSDWFFS----------------------DDEDKGERTPVDDKEPQSVPNIEYLLPN-------------------------IGRTVPPSDPGSDSTTCSSAKSKGSWVPKKEPYAREMLAISFISAVNRKRKKRR--------------------------------EARGLGSSTDDDSEQEAHK-------------------------------------------AAVGTQEPPEGQLPGPSAEEAPGRLSPSTAPDERP--------------------------------AADTRSIVSGYSTLSTMDRSVCSGTGGRRAG----------------------------AGDEADDERSE----------------------------LSHVETDTEG--GAGPG-------GRLARRP--------------------------SFSSHHLMPCDTLARRR---------------LSRSRADAEGP---------RGPEPLGSASSSS-----------------------QESLRPPAAAPVLGSRP--------SRVEALRLRLRG---------------------TADDMLAVRLRRPLSPETRRRRSSWRRHTVVVQSPLTDLNF------------------------------NEWKELDGGGPPESAGVRPHSDNKDSGLSSLESTKARA-SSAASLP--SGDLGALQGLPARRSAAARLHQCL------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q69ZH9-1", "uniprot_id": "RHG23_MOUSE", "id": "Q69ZH9-1", "name": "Rho GTPase-activating protein 23", "aln": "-----------------MNGVAFCLVGIP----PRPEP--------------------------------------RPPQLP--LGPRDGCSSGRPLP--------------WPGPRTLLLRKSLQDGFGFTLRHFIVYPPE---------------------SAVHCILKEEENGGRGG-----------------------------GPSPRHRLEPMDTIFVKNVKDGGPAHRAGLRTGDRLVKVNGESIIGKTYSQVIGLIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNE-----------------------------------------------------PYSGEARSIPEPPPLCYPRKTYAP------PTRAPAWATMVPEPISALPPDPRSPAAWS----------------------DPGSRVPSATRAHLDNSSLGMS------QPR-----------------PSPGAFPHLPSE-------------SRTPRAFP-EPGSRVLPSR-LECQQALSHWLSNQIPRRAGERR-------CPAMPPRARSASQDRLEDVTTHHP-------WPCSTSQDALSQLGQ---------------------------EGWHRARSDDYLSR----ATRSAEALG-PGALVSPRLERCGWASQRPS-------------------------------------ARTSACPSRDLT--QAPPPSGLQGLDDIGYIGYRSYSPSFQRRTG--LLHALSFRDSPFGG---LPTFSLAQSPASFPPEASEPP-------------------RVVRPDPSTR-ALEPPAEDHRDEVVLRQKPPTGR---KVQLTPARQMNLG-------FGDESPEPEA--RGERLGR----KVAPLATTEDSLASIPFIDEPTSPSIDLQAKHVPASAVVSS-AMNSAP---VLGTSPSSPTFTFALSRHYSQDCSSIKAGRRSSYLLAITTERSKSCDDG-----LNTFRDEGRVLRRLPSRVPSLRVLRSFFTDGSLDSWGTSEDADAPSKRHSTSDLS------DATFSDIRREGWLYYKQILTKKGKKAGGGLRQWKRVYAVLRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRAIRENSRAEGEDP-------GCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQT-----AVRGLRTQEQPPGSKEDSVAAPKTPWGINIIKKNKKAAP-------------------RAFGIRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPSDIN--LQDERWQDLNVISSLLKAFFRKLPEPLFTDDKYNDFIEANRIEDSRERMKTLRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHSDWFFS----------------------DDEDKGERTPVDDKEPQSVPNIEYLLPN-------------------------IGRTVPPSDPGSDSTTCSSAKSKGSWVPKKEPYAREMLAISFISAVNRKRKKRR--------------------------------EARGLGSSTDDDSEQEAHK-------------------------------------------AAVGTQEPPEGQLPGPAAEEAPGRLSPPTAPDERP--------------------------------AADTRSIVSGYSTLSTMDRSVCSGTGGRRAG----------------------------AGDEADDERSE----------------------------LSHVETDTEG--GAGPG-------GRLSRRP--------------------------SFSSHHLMPCDTLARRR---------------LSRSRAEAEGPGAGTARACPRGPEPPGSASSSS-----------------------QESLRPPAAAPALGSRP--------SRVEALRLRLRG---------------------TADDMLAVRLRRPLSPETRRRRSSWRRHTVVVQSPLTDLNF------------------------------NEWKELGGGGPQESVGVRPHSDNKDSGLSSLESTKARA-SSAASLP--SGDLGALQGLPQRRSAAARLHQCL------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q9P227-1", "uniprot_id": "RHG23_HUMAN", "id": "Q9P227-1", "name": "Rho GTPase-activating protein 23", "aln": "-----------------MNGVAFCLVGIP----PRPEP--------------------------------------RPPQLP--LGPRDGCSPRRPFP--------------WQGPRTLLLYKSPQDGFGFTLRHFIVYPPE---------------------SAVHCSLKEEENGGRGG-----------------------------GPSPRYRLEPMDTIFVKNVKEDGPAHRAGLRTGDRLVKVNGESVIGKTYSQVIALIQNSDDTLELSIMPKDEDILQLAYSQDAYLKGNE-----------------------------------------------------PYSGEARSIPEPPPICYPRKTYAP------PARASTRATMVPEPTSALPSDPRSPAAWS----------------------DPGLRVPPAARAHLDNSSLGMS------QPR-----------------PSPGAFPHLSSE-------------PRTPRAFP-EPGSRVPPSR-LECQQALSHWLSNQVPRRAGERR-------CPAMAPRARSASQDRLEEVAAPRP-------WPCSTSQDALSQLGQ---------------------------EGWHRARSDDYLSR----ATRSAEALG-PGALVSPRFERCGWASQRSS-------------------------------------ARTPACPTRDLPGPQAPPPSGLQGLDDLGYIGYRSYSPSFQRRTG--LLHALSFRDSPFGG---LPTFNLAQSPASFPPEASEPP-------------------RVVRPEPSTR-ALEPPAEDRGDEVVLRQKPPTGR---KVQLTPARQMNLG-------FGDESPEPEASGRGERLGR----KVAPLATTEDSLASIPFIDEPTSPSIDLQAKHVPASAVVSS-AMNSAP---VLGTSPSSPTFTFTLGRHYSQDCSSIKAGRRSSYLLAITTERSKSCDDG-----LNTFRDEGRVLRRLPNRIPSLRMLRSFFTDGSLDSWGTSEDADAPSKRHSTSDLS------DATFSDIRREGWLYYKQILTKKGKKAGSGLRQWKRVYAALRARSLSLSKERREPGPAAAGAAAAGAGEDEAAPVCIGSCLVDISYSETKRRHVFRLTTADFCEYLFQAEDRDDMLGWIRAIRENSRAEGEDP-------GCANQALISKKLNDYRKVSHSSGPKADSSPKGSRGLGGLKSEFLKQS-----AARGLRTQDLPAGSKDDSAAAPKTPWGINIIKKNKKAAP-------------------RAFGVRLEECQPATENQRVPLIVAACCRIVEARGLESTGIYRVPGNNAVVSSLQEQLNRGPGDIN--LQDERWQDLNVISSLLKSFFRKLPEPLFTDDKYNDFIEANRIEDARERMRTLRKLIRDLPGHYYETLKFLVGHLKTIADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHSDWFFS----------------------DEEDKGERTPVGDKEPQAVPNIEYLLPN-------------------------IGRTVPPGDPGSDSTTCSSAKSKGSWAPKKEPYAREMLAISFISAVNRKRKKRR--------------------------------EARGLGSSTDDDSEQEAHKPGA--------------------------------------GATAPGTQERPQGPLPGAVAPEAPGRLSPPAAPEERP--------------------------------AADTRSIVSGYSTLSTMDRSVCSGASGRRAG----------------------------AGDEADDERSE----------------------------LSHVETDTEGAAGAGPG-------GRLTRRP--------------------------SFSSHHLMPCDTLARRR---------------LARGRPDGEGAG----RGGPRAPEPPGSASSSS-----------------------QESLRPPAAA--LASRP--------SRMEALRLRLRG---------------------TADDMLAVRLRRPLSPETRRRRSSWRRHTVVVQSPLTDLNF------------------------------NEWKELGGGGPPEPAGARAHSDNKDSGLSSLESTKARAPSSAASQPPAPGDTGSLQSQPPRRSAASRLHQCL------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M1RNB3-1", "uniprot_id": "A0A8M1RNB3_DANRE", "id": "A0A8M1RNB3-1", "name": "", "aln": "MWSAGQVPLAMPVVCPHVGGKEWCFQDAVGVDCSSPEPRCIWVAVLHGDTQQINISNLQNDSSPNINGISAGKALSRPAQTSRAKGRRDGLSSSSENPRPVVRSGTDGLGVSWQGPRTLVLQKNSQ-GFGFTLRHFIVYPPE---------------------SALHTTLKDEENGNGKG-------------------------------LQRSRLEPMDTIFVKNVREKGPAHLAGLCTGDRLVKVNGESVLGKTYSQVIALIQNSESVLELSIMPKDEDVLQLAYSHDAYLRGNN-----------------------------------------------------PYTGKAQNLPPPPPVLYPPRTKSQSPAGFSPCPPPASSHMGQNQLDNWSRWPGSSAGPSPPLDNRTVASSNVVWAAEGRNCEPGGVGHSSPAHRTEEIQYGMTDRG--QQPTGQMRGRSYSSSSSSGGMMSPLHHGHLANHNMGTAMGHTGGRKGSPPWASPSQPTSTPSSSRNERTQQALSNWYYSQVPGRERERERERERSSSRSMHPRHRSFSQDRLGELGKARRSQ--QAGFPHSASQDTLLLLQQSAAAYADPYWNHGDWRGEHMYGQHPSVVAYGRKSSENLLASRYGHSGRSLENLDRAVGILSPRVERSAWVQQPPNRTEVYARHAGHFGQHIESPHQMHHTPQHHQNLTHATHQHSSQIPQPQQAAPMARRLPSCQSLDEE-PIGYRSYSPSFNRKTGRILQQAQSFRDPSYTGPHLWTPTSKTSPPEGHPPSATASPAPPTTSSSTTISTPSEGQDRTYRPTNHDRGAGEATSEAQTQEVVLRQKPPTGRRGANALRHPHYAIALDS-SDPLLFTTDPTEPTAKAESAISHRRTDVNLPPLSIEDDSLASIPFIDEPTSPSADLRARHVPASSVVSSGGINSAP---AVITSPASPTFTFPLNRLFSHNCSDPKSNRRSSYLLAITTERSKSCDEG-----LNAYREEGRVFSRLPKRV------KSFFTEGSLDSLGAAEEARS--KRHSTSELG------NISYSDVKREGWLHFKQIHTEKGKKVGSAIWPWRRVFSVLRTHSLFLYKDKRE---AVLKGAQLGGGAEDEQPISIRGCLVDIAYSETKRKHALRLTTQDFCEYLLQAEDREDMLEWIRVIRDNSKTDNEEL-------GFSRQALINKKLNDYRKQSP-TGNKPDSSPRVHR------MTFLLSK-----PDNSAPPRS-PKHEAKDESSPPKSPWGINIMKKSKKAGP-------------------KAFGVRLEDCQPAVNNKFIPQIVEICCGLVEDMGLEYTGIYRVPGNNAVVSSLQEQLNKG-VDIN--ITEEKWQDLNVVSSLLKSFFRKLPEPLFTDDKYNDFIDANRMENASDRLRTMKKLIRDLPDHYFHTLKFLVGHLKTVADHSEKNKMEPRNLALVFGPTLVRTSEDNMTDMVTHMPDRYKIVETLIQHYTWFFC----------------------EEQDKDEKTPVDTEDVQPAPNIDHLLSN-------------------------IGRTGMLG-EASDSTNSDSAKSKGSWGSKRDFTAKDILTLSIMSAVTRKRRKRH--------------------------------NGRLLGSSTDDDSEHEPIKSCISEKDDLQEMGQVASFCAPRAEGEEDDDEEEEDDEEEEEGAERQKAQEQKETVVPSISSTEEVTSTVLLSEEEEQKSEVKGGRSWR----------------------LDDARSIVSGYSTLSTLGRSLASEGRGEDADDEHSELVSETDNESG------------FASRSLTQERPEKPNRSNQ------NSHASPEPTAPQSFLYAHCKSPTPSGSATAPSPP----SQHITTNPEDSAARSSTPSTSSYSSSASQRLHNRSFNSHRLIQCDTLARRRTKADKAKAPSVDLSELSSSSAAEEDRQSGANQIPDSSPSPSSKAKGFS-----------------------IRNECTPISMVGPGSKGCVLSPGQGSLADQVRARLMG---------------------SADDLCSVGLRKQLSPETRRKRRAWRRHTVVVSP--TDCSD------------------------------KKPTVQS----TKPLASPSPVEKQDVRESHPECSETEAPTARRAVP------------------TSRFRDFL------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JEI9-1", "uniprot_id": "X2JEI9_DROME", "id": "X2JEI9-1", "name": "", "aln": "-------------MLQNSNGAAAAHSAASAVATPAAAAS------------------------------------AAAAAAAAAVAAAANNAALAASS---------------IQPKLIVIRRRPNQGFGFTLRHFIAYPPEDDQASSSASGLVSGSATAATAASVSTNWPQEASSAAGSNSGSSSSVGVAG--------ITGLEPTSPTSLPPYQVKAMETIFIKEVQANGPAHYANLQTGDRVLMVNNQPIAGIAYSTIVSMIKQTPAVLTLHVVPKECDVLQMHYTSIAHTPESNRLTMSTHSPSLLANGSHKTTFPAAAAVAAPPHQHQQQQQQLISYPAVAAVTTSTPAGSPQSQSQSQSHSHPNTHHAPSLHGGSRSGSITSTASGGITVLSQPFYPQQQQQQQQQQQHRHPALTGGSSSIDFGDMAHGLRQHQQQQQHLYQQQQQHHQFMRANQPPNLTVLSASSATNTPTPTARQPKSATSHNQALYAVGAGPSSAAGSGSGSLSGGSENSDLMIRLRESIKQKEEFLKSPVPASMSSASSINGNQAQSSSPAQQQHLQQHQQHFFPSHTPPGGVQVVVPPPRSRHQVMLKQQQ---------------------QQQQQHQQHHVLGYDMYHSGGKLVQRSSTAPGSVCHQHQQQQQHHLYHQQQHQQLQQTQHRQVMINNNAKYAKDLDYFETLQETGVTNKVFERKLVSHMSKGFDPFKPLSINTSALESSASTSSTSATTTVKKQSVLYESLQQHPLAKYHQTQQQTTTTTTVDGQTSSRMELHKATLANATIDPVPVGSSKFVTLPDKPDKGSSVATLADIAESSAAAIVDSASGSGNVVRRYKPLSSSSFDEGKPMRRISYLRATNNETDFNAEAAAGGDAAATGASGPASASAASSAPGPTPSSAPAPAPAPAPLPISIPIPVAAVVEPQKTKSLVEEHPDPTYDVIGGTGGGHEFIETPNGLEDVRLSAHGSRRASMSSDMRSSIHIDAELNGKYVPNELEAFETEIEIKSSCINGKRMSEYRSWRQVKLEIKGDLLRIYSGRHAKSEHNVIELDIRNFKFFDESMDKKKYLIRMQSKPSPSGAHLASLGNELNLDEGHDKLLTSSGSSSANEPAANAASALTASTSSSTCSSGPYTEILFKTKSSNEMKRLFGLLQWKDSLNYDDNEHQPQGKQLAEPQKTVASASYLDDVQGGASAADSSPLSSHSGGIADASGSHHVSALPAAAAIVAATSDSISPVMKARKSSSHKHIPDKDLGSPKSKNWKDLLFRRGGSGSGGVSHHDLASPSACAAKQIGSIGVPLRSCPMSKVNAYVPHLVEVCTNIVETKGLGVVGIYRIPGNKAAISELSELVNTKDFQFESCASDDRWEDVNVVSSLLKLFIRSLPDALMPASYYINFIEADKKFG-LERIVLLREIVESLPRHPYETMKHLIRHLCRVSGNCDVNRMEPKNLAIIFGPSIIRTPNDTLETAVKDMKHQCRIVELLVTQYDYFFEGGSLPDIAEVSGGTAAVSAAQPQQQTQEDQTSMLLHNLSKIERITERETTRTSRFMPQLRRKTHGKRSAVNSDTYSGESVLVSGSSSNTTTTTTTTTHTTSSTSSSNTITTTISTTTIQQRRAQRKAVQSICDQALILLLPTPVSSVSLPFQSLDYAKASASASASASSTASTSSSSTLHSGGKASASSSSSSTTKFSSSSSSACSTTAVAISSSISATSSKLLSANFKKRSTGGFLGSRSSHQTRKASLDEKDSGQSSGSLGHSLGVGINLAKEQQRSSVDISILLTDDDSSSRLSDTGSMSLTTITDTLDSKLRNLRSGSESNDENGSPEFPKNRRHTLGQPLHMHSENIPYADESPERLFHQFCNPLETAPLSLHLSRSCTATNTIGGDEKPSKQSGGVAPLPPSLLKAAHKLQHSATVPIHQGSSTAPTSGAATPVGTPTGSGGAGAIPSRSSSSSVTTLTKSIQPRFSNYLSYERGNAAAGGAERVVGSAGGAASDDDSEGSTTSDPKEKLLLGERPSPSFFIERYNKKRRDHRLFRSASFNCRNYSTRHITAQTSGGVAAGVSGGVAGAVAVGVACCQALSTTGLTKDEKTDMNLTKKRQIQNKQNRSIKRRHTVGGPHDYSASNGGCSNHSHGHDLAAINYNHHNRHHQQQLLKLGSATSGGGGSGAAAAETTTTTTTTTTVLRRLGTGQAGAEASVALPASSSGSSSNNNNSPQSDGSNGNGGGVAGVASNAPPTGVGVGGNNSSGSSSNSSSTSTTPAGNGDQVLEVGIRIKNISRGRF", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .* . . . . .. . . . :. . *: ::: : : **********.**** ::: :* .. . :::.*:***:*:*: **** *.* ****:: **.:.: * :** ::.:*::: .* * ::**: *:**: *: *: .: . :*..:. . . . :* : . : : . * . . * : : . ** .. . : . . * . : ..: . :* . : .: : .*.: . * . *:. : * : . : ** . . : :: : .* . . . . . . : : :.: :: . .. . : .. . : . . :* * . .:: . . :*. . . . . : . : . .. . .: :* * .::*: . :* * :. .: .. : . ..**: . . .:: . . .. * * :.*:. ..: ::: : * .* * :. :.. : .:. * . . : . :: ..: .:.: :* . .: :: : .: . : . . . . * . . :: .: : : *: : .* * : :: . : : . :. . . * * :* .*:* :: . . . ... .**: ::: : :.. ::*: *..* : * :* :* * :** ** .****:***:*.:*.*.* :* ::: :::*:*:**:***** *:*.**:.*:. . * :**:*:: . :*: :::::..** * :.*:*.*: ** ::.:.: *:***:***::***:::**.:*.: *..* .: :*** *: : :** ::: : ::*.: .: . .* .. *.: . .*::*. ::.:: : .. . :: : :. :*: : .. .*** . *. .. : :: . . : . . : .:* :* :*:*: :: * . :. . :* .* . :. : ...* : .. * .: : .: : . . . ... .... * . .: . : : * : *: : * : . :.::.* ***** : . . . . . . . :: * :: . .. ", "identical_positions": 193, "similar_positions": 482, "identity": "8.39%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121022-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q76B58-1", "uniprot_id": "BRNP3_HUMAN", "id": "Q76B58-1", "name": "BMP/retinoic acid-inducible neural-specific protein 3", "aln": "MIWRSRAGAELFSLMALWEWIALSLHCWVLAVAAVSDQHATSPFDWLLSDKGPFHRSQEYTDFVDRSRQGFSTRYKIYREFGRWKVNNLAVERRNFLGSPLPLAPEFFRNIRLLGRRPTLQQITENLIKKYGTHFLLSATLGGEESLTIFVDKRKLSKRAEGSDSTTNSS-SVTLETLHQLAASYFIDRDSTLRRLHHIQIASTAIKVTETRTGPLGCSNYDNLDSVSSVLVQSPENKIQLQGLQVLLPDYLQERFVQAALSYIACNSEGEFICKENDCWCHCGPKFPECNCPSMDIQAMEENLLRITETWKAYNSDFEESDEFKLFMKRLPMNYFLNTSTIMHLWTMDSNFQRRYEQLENSMKQLFLKAQKIVHKLFSLSKRCHKQPLISLPRQRTSTYWLTRIQSFLYCNENGLLGSFSEETHSCTCPNDQVVCTAFLPCTVGDASACLTCAPDNRTRCGTCNTGYMLSQGLCKPEVAESTDHYIGFETDLQDLEMKYLLQKTDRRIEVHAIFISNDMRLNSWFDPSWRKRMLLTLKSNKYKSSLVHMILGLSLQICLTKNSTLEPVLAVYVNPFGGSHSESWFMPVNENSFPDWERTKLDLPLQCYNWTLTLGNKWKTFFETVHIYLRSRIKSNGPNGNESIYYEPLEFIDPSRNLGYMKINNIQVFGYSMHFDPEAIRDLILQLDYPYTQGSQDSALLQLLEIRDRVNKLSPPGQRRLDLFSCLLRHRLKLSTSEVVRIQSALQAFNAKLPNTMDYDTTKLCS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PJM5-1", "uniprot_id": "A0A8M9PJM5_DANRE", "id": "A0A8M9PJM5-1", "name": "", "aln": "-MWARSVGPRPPDPMLLWEGMVLCVRWACVLVSVALYVGSAEPLGWLLSDKGPFHRSQEFIEFTERYQHGFTTRYKIYREFGRWKVNSLAAERQEGNGAAVPFDPEFIHNVRLLGRRPSLQKITDTIIKKYGTHFLLSATLGGEESLTIFVDKSKLSRGQQNGDVSNGTGGSLTLEALHQLAASYFIDRDSTLRKLHHLQIASTAIKVTETRTGPLGCSNYDNLDSVSSVLVHSHENKVQLQGLQAILPAYLRSGFVQAALGYIGCNAEGQFVCKDNDCWCQCAAEFPQCNCPEADIHSQESYLERMRDAWRLENQEFQHSDEFQSFMGKLPTQSALNSSRIQQLWRTDSALQQRYRQLESRISLLLSKTRRTANKLFSLSKRCRTQPKIVSLRERPLSYWLQFTLSILYCSENNQLGFYTEELRTCACPYENPSCQSVIPCEVGDGHRCASCSVDNRTRCSSCNPGYVLSHGVCKYAVPNPTDHYLGFETDLQDLELRYLLQHRDGRITTHAIFVSNDVRLNVWFDPSWRKRMLLTLKSNKFKSSRVHMLLGVSVQFCMTKNSTIEPVFSVYVNPFGGSHSESWTMPINQNSYPDWEKTKLDIPLDCFNWTLTLGNRWKSFFETVHFYLRGRIRTESSQGNETVYVEPLEATDASQNFGYMKINSMQLFGYSMHFDPEAIQDLILQLDYPYTQGSQDSALLQLMEIRYRVNRLSPPGPLPLDLFSCLLRHRLKLSSSEVQRILATLQTFSAKQPFYKEYEAAKLCS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* .*.. . * *** :.*.:: : *:.. ::.*:.**************: :*.:* ::**:***************.**.**:: *:.:*: ***::*:*******:**:**:.:************************** ***: :..* :..:. *:***:*****************:***:*********************************:* ***:******.:** **:. ******.**.**:**:*:**:*****:*..:**:****. **:: *. * *: ::*: *.:*:.****: ** :** : **:* * :** ** :*:**.***. :. *: *::: .:*********:.** * *:*. :*** *:***.**. ** ::** ::*:** :: * :.:** ***. * :*: ******.:**.**:**:*:** *.:.****:**********::****: * ** .****:***:*** ******************:*** ***:**:*:*:*:*****:***::************** **:*:**:****:****:**:*:********:**:******:***.**:::..:***::* **** *.*:*:******.:*:************:**********************:*** ***:***** ***************:*** ** ::**:*.** * :*:::****", "identical_positions": 490, "similar_positions": 184, "identity": "63.89%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121022-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8NCL9-1", "uniprot_id": "APCDL_HUMAN", "id": "Q8NCL9-1", "name": "Protein APCDD1-like", "aln": "MPAA----------MLPYACVLVLLG-----AHTAPAAGEAG-GSCLRWEPHCQQPLPDRVPS---TAILPPRLNGPWISTGCEVRPGPEFLTRAYTFYPS--RLFRAHQFYYEDPFCGEPAHSLLVKGKVRLRRASWVTRGATEADYHLHKVGIVFHSRRALVDVTGRLNQTRAGRDCARRLPPARAWLPGALYELRSARAQGDCLEALGLTMHELSLVRVQRRLQPQPRASPRLVEELYLGDIHTDPAERRHYRPTGYQRPLQSALHHVQPCPACGLIARSDVHHPPVLPPPLALPLHLGGWWVSSGCEVRPAVLFLTRLFTFHGHSRSWEGYYHHFSDPACRQPTFTVYAAGRYTRGTPSTRVRGGTELVFEVTRAHVTPMDQVTTAMLNFSEPSSCGGAGAWSMGTERDVTATNGCLPLGIRLPHVEYELFKMEQDPLGQSLLFIGQRPTDGSSPDTPEKRPTSYQAPLVLCHG--EAPDFSRPPQHRPSLQKHPSTGGLHIAPFPLLPLVLGLAFLHWL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q271-1", "uniprot_id": "A0A8M9Q271_DANRE", "id": "A0A8M9Q271-1", "name": "", "aln": "MAGERLIHLLRTIWMVFLMQVLSVRGSKLWEVPTAPLVPHTNLSTRLFWEPQCQAQLRHLQNEGRITATIPPKLEGHWVSSRCEVRPGPEFLTRSYTLYQSPTRLFRALQHYYSDSECQVPTYSLVIRGKLRLRQASWITRGATEAEHHLHKVGMVIHSQKAIHHLATRLPSSCLGLKAEGHLVLHR------FYELFNAKAEKDCLGALGFSMMELELLRVETHHHPHGRP----AQELFLGDVHTEWNERVHYRPSGYQEPLQNAMHHIHPCPVCGLVYRASEQHPPILPPSPSIPLNLNGNWVSQRCESRPAVLFLTRLFVFNEEQHTWEGTYHHYSDPTCRQPSFTLSASGNYVKVGQSIKVRGATELVFKVTHAKVIVFDRALLRELNSTQNGRCGQAGGWEAGIEQDITWTNGCDALGIRLPHKEYELFKMEVDRKGHPLLFNGERPTDGSSPERPAKRPTSFQTPMVQCSTSVRVEPHHSPYSDHSKGPKKSSANALHSS--VILLSLLNAWIIHLF", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.. *: ** : * . *** . .:. .: * ***:** * . . ** :**:*:* *:*: ************:**:* * ***** *.**.*. * *::**:::**:***:***:*******::******:*:**::*: .:: ** .: * .. :* * :*** .*:*: *** ***::* **.*:**: : :*: *. .:**:***:**: ** ****:***.***.*:**::***.***: *:. :***:***. ::**:*.* ***. ** ***********.*: ..::*** ***:***:****:**: *:*.*.: * :***.*****:**:*:* :*:. ** :: . ** **.*. * *:*:* **** .******* ******** * *:.*** *:********: * *****:*:*:* * .. . * ..:.. *:.*:..** : :* :*. ::* :", "identical_positions": 251, "similar_positions": 140, "identity": "47.9%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121023-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q868T3-1", "uniprot_id": "CCAPR_DROME", "id": "Q868T3-1", "name": "Cardioacceleratory peptide receptor", "aln": "MLHLRLFDSSLYYTLASASESSGLASSTSTERSFNGTQGAGGVAAGGESLTPTDVAAVNLTYFTPAISHVMLAPTTIATTTASATMVQIQTTAAPSHDLETGGNSTSSDPGEFDNLNSFYFYETEQFAVLWILFTVIVLGNSAVLFVMFINKNRKSRMNYFIKQLALADLCVGLLNVLTDIIWRITISWRAGNLACKAIRFSQVCVTYSSTYVLVAMSIDRYDAITHPMN-FSKSWKRARHLVAGAWLISALFSLPILVLY-EEKLIQGHPQCWIELGSPIAWQVYMSLVSATLFAIPALIISACYAIIVKTIWAKGSIFVPTERAG---FGAAPARRASSRGIIPRAKVKTVKMTLTIVFVFIICWSPYIIFDLLQVFGQIPHSQTNIAIATFIQSLAPLNSAANPLIYCLFSSQVFRTLSRFPPFKWFTCCCKSYRNNSQQNRCHTVGRRLHNSCDSMRTLTTSLTVSRRSTNKTNARVVICERPTKVVTVPAMSEV", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "E7F1C0-1", "uniprot_id": "E7F1C0_DANRE", "id": "E7F1C0-1", "name": "", "aln": "-----------------------------------------------------------------------------------MPFSFTLNLSNTSVEMDTSADEPRNEQ-----------LAQIEIALLSVIFLCASTLNFSLLLVLWRKRQQMSRMRVFVTHLCLADLVVAFFQVCPQLMWDITDRFVGPDLVCRLVKYLQVVGMFASTYMIVVMTVDRYQAICNPMVTFQRRRARWNLPVCVAWLVSFVLSVPQLFIFSRVQIAPGVYDCWAEFVQPWGPKAYVTWTTLVIFLVPVVMVTACQVRICRALQINLYLKTQQQQRGDEGHSHPLSSRASNVVSVSKSRIKTVKMTVVIVLAYTVCWAPFFTVQLWSVWDDDAPTET--ATFTILMLLASLNSVANPCIYLLFT-------VKFPELLGSLLCMKHAEKK--------------EPLPEETTMVSSLYLSFKSHSDIR---------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .: . : .* :::*..:.. .: ::*:* ::* * ::*:*:: :::: ***. *:.:*.**** *.:::* .:::* ** : . :*.*: ::: ** ::***::*.*::***:** :** *.: * . *. ***:* ::*:* *.:: . :: * :** *: .* . :.*:: .: .:* :*.::::** . * ::: : : . :: * .. . : ***. :.::::******:.**:.: :**:*:: .:* .*:.: . ::* * *:: **.***.*** ** **: :** : * * .:: :. . *:.:** :* :* .. . ", "identical_positions": 100, "similar_positions": 150, "identity": "20.04%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121024-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6PB70-1", "uniprot_id": "ANO8_MOUSE", "id": "Q6PB70-1", "name": "Anoctamin-8", "aln": "-------MAEAASGAGDVTLE---------------GERGKRPPPEGEPAAPASGVLDKLFGKR----------------------LLQAGRYLVSHKAWMKTVPTEDCDVLMTFPDTTDDHTLLWLLNHIRVGIPE---LIVQVRHHRHTRAYAFFVTATYESLLRGADELGLRKAVKAEFGGGTRSFSCEEDFIYENVESELR---FFTSQERQSIIRFWLQNLRAKQG--EALHN-VRFLEDQPIIPELAARGIIQQVFPVHEQRILNRLMKSWVQAVCENQPLDDICDYFGVKIAMYFAWLGFYTSAMVYPAVFGSVLYTFTEAD-QTSRDVSCVVFALFNVIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVEEPRPQFRGIRRISPIT-RAEEFYYPPWKRLLFQLLVSLPLCLACLICVFILMLGCFQLQELVLS---VKGLPRLVRFLPKVMLALLVSVSAEGYKKLAVWLNDMENYRLESTYERHLIIKVVLFQFVNSYLSLFYIGFYLKDMDRLKE--------------------------------------------MLATLLITRQLLQNVREVLQPHLYRRLGSGELGLRTILELARALLGLLNPLRPDPRRHLEAQADEGGAGS-----RRCLGGGCGAPEEEN----------EEEEEAAVERRPAGEGGEVPEGPRGGKEEDE--EEDDD-EDEDEEYEGEEGSLLDCG---LRLKKVSFAERGAGRRRPGPSP--DGLLEEGSPTMVEKGLEPG-VFTLAEEDDEPEGPPGSPGPEPQTVLLRRARGEGRDQGPDGDRDTETGS-GDAAGRQK-RHNRSSWIDPPEEEHSPQLTQAELESCMKKYEDTFQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEIRSDAFKLCTGLQRPFGRRVESIGQWQKVMEAMGVLAIVVNCYLIG-------QCGQLQRLFPWLSPEAAIVSVVVLEHLALLVKYLIHVAIPDIPGWVAEEMAKLEYQRREAFKRHERQAQQRFQQQQRRRR-------------------------EEEERQRHAEQQARRERDTGGREEARAEAPGPDPVA--ERGAAKAKGS-------ERPRRPGALLPPGPVLRLKQIIPLQ--------TRPPAPTGCAPPPRSP-------ADTRLPAFLSLRFLKAP-----------------------ERGPSPP---RPGKLFAFSAR--EPSANGAPG----------GGARAHRS-AGDEPAAAEPE-PRPEDAG-----------------------------HRP-------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I6GCQ3-1", "uniprot_id": "A0A8I6GCQ3_RAT", "id": "A0A8I6GCQ3-1", "name": "Anoctamin", "aln": "-------MAEAASGAGDATLE---------------GERGKRPPPEGEPAAPASGVLDKLFGKR----------------------LLQAGRYLVSHKAWMKTVPTEDCDVLMTFPDTTDDHTLLWLLNHIRVGIPE---LIVQVRHHRHTRAYAFFVTATYESLLRGADELGLRKAVKAEFGGGTRSFSCEEDFIYENVENELR---FFTSQERQSIIRFWLQNLRAKQG--EALHN-VRFLEDQPIIPELAARGIIQQVFPVHEQRILNRLMKSWVQAVCENQPLDDICDYFGVKIAMYFAWLGFYTSAMVYPAVFGSVLYTFTEAD-QTSRDVSCVVFALFNVIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVEEPRPQFRGIRRISPIT-RAEEFYYPPWKRLLFQLLVSLPLCLACLVCVFVLMLGCFQLQELVLS---VKGLPRLVRFLPKVILALLVSVSAEGYKKLAVWLNDMENYRLESTYERHLIIKVVLFQFVNSYLSLFYIGFYLKDMDRLKELLLLLSLTQSLERQLRAALVPLAALRFRLLLLSLRGLLLVARAKMLATLLITRQLLQNVREVLQPHLYRRLGSGELGLRTILELARALLGLLNPLRPDPRRHLEAQADEGGAGS-----RRCLGGGCGAPE--------------EEEEVAVERRPAGEGGEVPEGPRGGKEEDE--EEDDDDEDEDEEYEGEEGSLLDCG---LRLKKVSFAERGAGRRRPGPSP--DGLLEEGSPTMVEKGLEPG-VFTLAEEDDEPEAPPSSPGPEPQTVLLRRAGGEGRDQGSDGDRDPETGS-GDAAGRQK-RHNRSSWIDPPEEEHSPQLTQAELESCMKKYEDTFQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEIRSDAFKLCTGLQRPFGQRVESIGQWQKVMEAMGVLAIVVNCYLIG-------QCGQLQRLFPWLSPEAAIVSVVVLEHLALLVKYLIHAAIPDIPGWVAEEMAKLEYQRREAFKRHERQAQQRFQQQQRRRR-------------------------EEEERQRHAEQQARRERDTGGREEARAEAPGPDPAA--ERGAAKAKGS-------ERPRRPGALLPPGPVLRLKQIIPLQ--------TRPPAPTGCAPPPRSP-------ADTRLPAFLSLRFLKAP-----------------------ERGPSPP---RPGKLFAFAAR--EPAANGALG----------GGARSHRS-AGDEPAAAELE-PRPEDAG-----------------------------HRP-------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9HCE9-1", "uniprot_id": "ANO8_HUMAN", "id": "Q9HCE9-1", "name": "Anoctamin-8", "aln": "-------MAEAASGAGGTSLE---------------GERGKRPPPEGEPAAPASGVLDKLFGKR----------------------LLQAGRYLVSHKAWMKTVPTENCDVLMTFPDTTDDHTLLWLLNHIRVGIPE---LIVQVRHHRHTRAYAFFVTATYESLLRGADELGLRKAVKAEFGGGTRGFSCEEDFIYENVESELR---FFTSQERQSIIRFWLQNLRAKQG--EALHN-VRFLEDQPIIPELAARGIIQQVFPVHEQRILNRLMKSWVQAVCENQPLDDICDYFGVKIAMYFAWLGFYTSAMVYPAVFGSVLYTFTEAD-QTSRDVSCVVFALFNVIWSTLFLEEWKRRGAELAYKWGTLDSPGEAVEEPRPQFRGVRRISPIT-RAEEFYYPPWKRLLFQLLVSLPLCLACLVCVFLLMLGCFQLQELVLS---VKGLPRLARFLPKVMLALLVSVSAEGYKKLAIWLNDMENYRLESAYEKHLIIKVVLFQFVNSYLSLFYIGFYLKDMERLKE--------------------------------------------MLATLLITRQFLQNVREVLQPHLYRRLGRGELGLRAVWELARALLGLLSLRRPAPRR-LEPQADEGGGGGSGGGGRRCLSGGCGAPEE-------------EEEAALVERRRAGEGGEEGDGPPGGKEEDEDDEEEEDEEEEEDEEEGEEGGLLDCG---LRLKKVSFAERGAGRRRPGPSP--EALLEEGSPTMVEKGLEPG-VFTLAEEDDEAEGAPGSPEREPPAILFRRAGGEGRDQGPDGGPDPEPGSNSDSTRRQR-RQNRSSWIDPPEEEHSPQLTQAELESCMKKYEDTFQDYQEMFVQFGYVVLFSSAFPLAALCALVNNLIEIRSDAFKLCTGLQRPFGQRVESIGQWQKVMEAMGVLAIVVNCYLIG-------QCGQLQRLFPWLSPEAAIVSVVVLEHFALLLKYLIHVAIPDIPGWVAEEMAKLEYQRREAFKRHERQAQHRYQQQQRRRR-------------------------EEEERQRHAEHHARREHDSGGREEARAEGSGLDPATSSEKASAKAKGSTAGGHGPERPKRPGSLLAPNNVMKLKQIIPLQGKFLSSGATSSLAAAGAGATTRPPPAQSPTGSDTRLPAFLSFKFLKSPETRR-----------------DSERSHSPPKAFHAGKLFPFGGTRAEPGSNGAGGQARPDGTPSSGSSRVQRSGPVDEALAEELEAPRPEEEGSGTALAPVGAPALRTRRSRSPAPPPPMPLPRPPTPPAGCWQWDGPWGCGGEGAAPRQALAAAECPPCAMAGPPPAPQPLPGDASFYSLPPPPLPPTSDPLETPAPSPSPSPSPQAVCWPSGWH", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8N7UT44-1", "uniprot_id": "A0A8N7UT44_DANRE", "id": "A0A8N7UT44-1", "name": "Anoctamin", "aln": "-MMPDTAAAAAASSASNISSSSDGESSRLRHRAQGDAERAEQQQHTAAPQTTSAGVLDKLFGKR----------------------LLQAGRHIMSHKSWMKTVPTENCDVLMTFPDTTDDHTLLWLLNHIRLGIPE---LIIQIRHHKHTRMYAFFVTATYENLLRGAEEMGLQKAVKPEFGGGSRSFSCEEDYIYENIESELC---FFTSQERQSIIKYWLDNLRAKHG--EALHN-IHFLEGQPIIPELRARGVIQQVFPLHEQRILGQLMKSWVQAVCEKQPLDDICDYFGVKIAMYFAWLGFYTTSMLYPAVIGFVLWMLTESD-QTSRDICCVVFALFNVVWATLFLERWKRRGAELAYKWGTLNTPAESLEEPRPQFRGVKRCSPVT-GCEEFYYPPWRRRVFRWLVSFPVCILCLCFVFLAMLVCFELQEFVMG---IKELPRVARFIPKIMLAITVTACDEVYRKIACWLNDMENYRLQSAYEKNLIIKMVLFQFVNSYLSLFYIGFYLKDMERLKE--------------------------------------------MLATLLIIRQFVQNMKEVLQPYLAERHRLGELTLRAVWELLVS--ALLKYGRLAAGRAQVSPSDP-----------TVLGPGLRGPQ--------------MGEEGHQDRRER----KCLNGGCGVPDEDM--EEEHGERHSEEENESE--SLIDCG---LKLRKVSFIEKVERKSASCVSPVDDSFLEEGSPTMVERGMDPASVFEMCDDEDENGAP-----------EMKELAAEPLPTGVENSSSVKLRKRGRSLERADSKTKRDSWMDPPEEQETNTLTQAEVEGCMQTYQDTFQDYQEMFVQFGYVVLFSSAFPLAAMCALINNIIEIRSDAFKLCTSLQRPFGLRVASIGQWQTVMEAMGLIAIIVNCYLIG-------QCGQLQRLFPWLSPEMAIISIVILEHFAVLLKYIIHVAIPDIPSWVGEEMAKLEFQRKEAFKKHERQAQQHFQQQQRRKR-------------------------EEEERQRQAEYQARRDRDDGRSDASGSDHHHEKSQSGKARSGGGGGSS-----GGEKPKRPSSLLGNNNVMKLKQIIPLQN----------KFSSGTARSPQSP-----TGNEPKLPGFLSFKFLKSPENKKEAAMASASASVAPPVQEKVERSQSPNKSFNPGKLFNFGKSEGGACVNGAQLSKLGD-----GGQMQDKPPTKSDLNGVPDEIPSPCGENGENG-------------------------SSSDADPSGPKM----------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9V416-1", "uniprot_id": "Q9V416_DROME", "id": "Q9V416-1", "name": "Anoctamin", "aln": "MHGNEEVRDGVPFSEQQQSSEDVPDSTATTTATSTAGELGGGPRDGGEDDFTDDNNFESNLRRRKGKIISCAKETIENASRQLRRKVPYAGHLMTPRRLWLNKIPTQ-CDVVIEFPEDAPDEALRWLLARIRSQPPAGLGLLVQVKAHESTRRNAFYVSAPVNVLFKAAEEARLPKRLRPDLGGALREFTTRESHCFQQLRGDVGSTALFTSQERQWLVLQVLQGLRAGCSDIEALHGRAAVAEGQSIVATWQESGLITQVFPLHEPSSLTQLQTHWVKQIFAPQPLDDIAAYFGVKVALYFAWLGHYTCALGVPAVFGTILYCILWGKGQTAQDMGHVLFSLFNVAWASLYLEAWKRYSVELAFRWGTLSTPPELLEPPRPLYKGPLEENNVTGRLEPKEAPAWQRRAFRYLVSFPIIGCCLCVVFAVMFLMLRFQDWWDSKLPEESVLCCLSVIPKVLLAGAITLMDEAYFKLAVWLNDRENYRLQSKYENHLIAKVALFQFVNSFLSLFYIAFYLRDEEKLKE--------------------------------------------QLAGLLISRQIIGNLRESAIPYFLEQWKLAKLSFNMWGALSPTQNVTRSLAEELATAEAELKAESTGTPTKSQQPESSSKRNIGQAEIESSLYKYDGTFSDHLEMLVQMGYVVLFSAAFPLAGVCALINNLMEIRSDAFKLAHVHQRPFGQRVANIGTWQNALSILSLAAVIVNCALIGLSGQVSRLWPGLTTAQTIILIVTLEHIMLGLRQALTWLLPELPSWLAAEIARAEHCRREMQCKGTSPRPTPPTPQSTTSTQPEQEGPGGLQMESGANTTRDQSMESQVAEDILLYGQEFAGYGHNIEADVNIYENRDSSPDSPPSQTSTILIRPLHESTPPHGGASLTSLHQDGNGGACQSWVKKSQMFIPEIPPYLGYSVRNLTTFAGNSRKMQQHQKLQSGASASTLALNSAAYAARMQSMHIQEIPPFRKKSTDSADHTGSSASSSPQRTTMRQLSAQREPQQQTIPEIPPYKTRKISAESAMHLNMSDKLHIKLHAPEWMSRLKVNDNANLHRSIDCISKELGNSADTADILKPAPSWCNVAMRSGAPGSNLATPPASQHQQQIVASSSSSSGGGGSVFSPSGPGPAGASGVGISNSQSRPSVGALSNSSSGSSHKQQLKQQAKEEKER----AKEEKERAKEEKERVKEKEKERLKEKEIEKAMEKEKEKDAQG-----AAASTSTAATDDEAKAAELAAKKSRLKQKLVKSARSVAIFSLKLKERRQREAEKAATIAVEHAKALAKLPMPQPVGGELSLIPIEQLIQIEDIIPAMKAASTSGATTSSSQAGPSTYHQQQHQQQHYHPPSNPHPHTDN------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " .. . : . .* . . . . ::. : :* : **: : .:: *::.:**: ***:: **: : *.:* *** :** * *::*:: *. ** **:*:*. : *::.*:* * * ::.::**. * *: .*.. ::::..:: :******* :: *:.*** . ****. . *.*.*:. *:* ****:** * :* . **: : ******. *****:*:******.** :: ***:* :*: : .. **::*: *:*:**** *::*:** *** ..***::****.:* * :* *** ::* . . :* * *.*:* *: ***:*: ** ** *: :.:*: . : : .:**::** :: * * *:* **** *****:* **.:** *:.*******:******.***:* ::*** ** *** **:: *::* *:: .: .:* :. * : . . . :: . .: * . :: ... . . . . : : * * :*: * . : :.: . : . : : : . . . . : : . . ::. : :::: : * : * .* . : : .: * :. . . :*. :: . . . : . * *. :: :: : ** .*: ::: . : . : .: : * : * :** : :. . :. .* . :* : :: . *:. :: :: . : :* * : . : : . . : :. *.: * . : :* * . .:* . . . . : .: . .: **. . . : : : .. . . .: . . ", "identical_positions": 226, "similar_positions": 310, "identity": "16.1%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121024-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8N6Y0-1", "uniprot_id": "USBP1_HUMAN", "id": "Q8N6Y0-1", "name": "Harmonin-binding protein USHBP1", "aln": "MSAR-----ATRPRSRRGRHAPPGELDPVAESSEEVEAASG--SSKPSFAPPPVSSGLEQLGPMEEVSGQGLGSRTDKKMDGGSGRELASAPEVPHKPAVEAHQAPEAALQYKETVPPGNGAPDVFQTLQHTLSSLEAAAAAWRHQPPSHSGPMEFEGTSEGGAGSLG-KQEGAGSCQREAARLAERNAWLRLALSSREDELVRTQASLEAIRAEKETLQKEVQELQDSLLRLEPCPHLSHNQAGGSGSGSSSSEADREPWETQDSFSLAHPLLRRLRSHSSTQILGSLPNQPLSPEMHIMEAQMEQLRGSIEKLKCFNRLLSAVLQGYKGRCEGLSMQLGQREAEATALHLALQYSEHCEEAYRVLLALREADSGAGDEAPMSDLQAAEKEAWRLLAQEEAAMDAGAQQNPQPSPEGSSVDKPTPQEVAFQLRSYVQRLQERRSLMKILSEPGPTLAPMPTVPRAEAMVQAILGTQAGPALPRLEKTQIQQDLVAAREALADLMLRLQLVRREKRGLELREAALRALGPAHVLLLEQLRWERAELQAGGAN--SSGGHSSGGGSSGDEEEWYQGLPAVPGGTSGIDGGQVGRAWDPEKLAQELAASLTRTLDLQEQLQSLRRELEQVAQKGRARRSQSAELNRDLCKAHSALVLAFRGAHRKQEEQRRKLEQQMALMEAQQAEEVAVLEATARALGKPRPPLPPPQLGDTFL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8R370-1", "uniprot_id": "USBP1_MOUSE", "id": "Q8R370-1", "name": "Harmonin-binding protein USHBP1", "aln": "MSAR-----ATRPRSRRGRHPLPGELDPVAESSEEVDANNGRFETKPELHQEYLGPGLQSP-----------RNWIKEGCDVGSHAVLSLSPEEQCEPEVEAHQVLQEAP--LDSGPAEISVPSVYETLQCRLSSLEAVVAALRHHSLSFPKSVEAEDRDQGAPGPFGDEKEDAGPGQQEAARLIERNAWLRLALCNREDELACTQASLQDAQAEKETLQRQVQELEDSLMQMEASPPTPILRAGRRNSNSSTSGAERRPWVPQDS-SMAHPFLQRLRSDSSTQSFGCLSTQHPAPETYLMEDQMGQLQGSIEKLKCFNRLLLAVLQGYKGRCESLSIKLAKREAEATALRLALQYSEDCEEVYEVLLALKMAGLGTGVGTTKGDLQAAEKEASRLLMKKEATMEV---ETPQPSSEGSGVDKPTPEELASQLHGYVQHLRERWALVKIPEELGPVTAPKATMPHAEATVQAILEIQPGPTLPHLEKSQIQQDLAATRDRLADLVLRLQLTQREKRGLELREAALRAQGPAHQLLLQQLRWERAHFAGDGSSGGSSEDPSSEEEAGEDRQQHYQGPLALLDG-------QMGKVWDSENVSQELSASLARAIDLRAQLQSLRQQLEQVTQKGRTRRVQSAELSRELCKAHSALALAFRGAHRKQEEQRLKLEQQVARLQAQQAEELAVLTATARALGKPGAPQP----AQTFL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F1E7-1", "uniprot_id": "E7F1E7_DANRE", "id": "E7F1E7-1", "name": "", "aln": "MTERSDSLVSVDSELAQCETEVNTLLQIISDLNRKMDSLQIPREMKACESEVQVSGCVLQQRPRS-------PACSLMSVETGPASVESVCGDSEGG-SSELWNRLQTLLSALETS-SGQGKKMLRLQTHNVEAISAKHLSAARESWVQATQVLEEMERDLGISYPSALPTDERRQYQREVLSLYKHNQDLNASLKSRQDELMGAEKTLVDLEDENKFLQEKVVDLKRKWLYGVSCSPPVSPSLSSSRTSSPCFSSPSYPGS---------PLLSRKLPSSRPDSP-----LPPSTIDSVLQAETEKMQRCLERLKARNERLSAALVRRKGESEQLSMSLSRQEADSSALHMALAYCEECEEAYSDLLSLYEARK-----QQHAATNSTPQPDLSKSKEENSKCESSSPPEGAADARPNSLSKQEFEDKAGVITQRISRLQQDRAAVCIPQR--GKAGEDKISPDTGTLAGVRGRASSLSKNNKEEKAALRYELDTVREEMSEMRGNLRLLEKERRCLDMSLMVQSAQDSATSLILDSLRDELGERR-------------AAQQRTAENLAKIEGGGGIPGP-------------RNHSILRELQAALQREQLLRTRVATLRESLDSALTDCTTNRRINREEIARLSRYYNKVSSTYRSSRKKQKEQLWRLEKQIAVMSERHATQEAELSSTVEAMEWRR--------EETVL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*: * :. .. : . *: ::: ..:::: . . *. :. : . : *. : . : * : : :: . . : : : :* *. . . :* . * . . . : *:*. * ::* *. :* .*:*** :: :* . *:: **.:* :*: . : ... . :.*. : * *:* * . * .: :. ::: : ::: .:*:**. *. * *.* **..* **:.*.::**:::**::** *.*.***.* **:* * . ::: : :::: : .... ..:.* :: * : :.:*:: : : * .. . * : : . . .. . : **: :: :* :.*: :::: .*:* .:*:* *:: . * ..* *:*:.** * .. : :. :* .: . ..: :** *:* * *: :: :**..*:.. . :.* . * *.: :. : ::*.:::**:** :**:*:* :. ::* : * * :*..*: :*.*", "identical_positions": 111, "similar_positions": 227, "identity": "15.57%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121026-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5QJU3-1", "uniprot_id": "ACER2_HUMAN", "id": "Q5QJU3-1", "name": "Alkaline ceramidase 2", "aln": "--MGAPHWWDQLQAGSSEVDWCEDNYTIVPAIAEFYNTISNVLFFILPPICMCLFRQYATCFNSGIYLIWTLLVVVGIGSVYFHATLSFLGQMLDELAVLWVLMCALAMWFPRRYLPKIFRNDRGRFKVVVSVLSAVTTCLAFVKPAINNISLMTLGVPCTALLIAELKRCDNMRVFKLGLFSGLWWTLALFCWISDRAFCELLSSFNFPYLHCMWHILICLAAYLGCVCFAYFDAASEIPEQGPVIKFWPNEKWAFIGVPYVSLLCANKKSSVKIT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q8VD53-1", "uniprot_id": "ACER2_MOUSE", "id": "Q8VD53-1", "name": "Alkaline ceramidase 2", "aln": "--MGAPHWWDHLRAGSSEVDWCEDNYTIVPAIAEFYNTISNVLFFILPPICMCLFRQYATCFNSGIYLIWTLLVVVGIGSVYFHATLSFLGQMLDELAILWVLMCALAMWFPRRYLPKIFRNDRGRFKAVVCVLSAITTCLAFIKPAINNISLMILGLPCTALLVAELKRCDNVRVFKLGLFSGLWWTLALFCWISDQAFCELLSSFHFPYLHCVWHILICLASYLGCVCFAYFDAASEIPEQGPVIRFWPSEKWAFIGVPYVSLLCAHKKSPVKIT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FCF4-1", "uniprot_id": "E7FCF4_DANRE", "id": "E7FCF4-1", "name": "Alkaline ceramidase", "aln": "MMMMDAHLWDHLQAGSSEVDWCEGNYLIYPGIAEFYNTISNVLFFVLPPILMCLFRQYATHFNSGIYLIWTLLVVVGIGSTYFHATLSFLGQMLDELAILWVLMCAIGMWFPKRYLPKIFRRDRSRFKMVIGVLSGITTCLAFIKPAINSITLMTLGIPCTALLITELKRCDNLRVFKLGLLSGLWWTLALMCWISDRIFCEMWSSVNFPYLHCAWHILICLASYLGCVCFAYFDAASEAPEQGPVVKFWPSEKWAFIGVPYVTLLCVHRKPSIKVT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * .* **:*:**********.** * *.**************:**** ********* *******************.*****************:*******:.****:********.**.*** *: ***.:******:*****.*:** **:******::*******:*******:*********:*****: ***: **.:****** ********:*************** ******::***.***********:***.::*..:*:*", "identical_positions": 220, "similar_positions": 41, "identity": "79.42%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121026-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q3URE1-1", "uniprot_id": "ACSF3_MOUSE", "id": "Q3URE1-1", "name": "Malonate--CoA ligase ACSF3, mitochondrial", "aln": "MPPHLALPFRR--LFWS-LASSQ------LIPRRHRGHSLLPTTPEAHTDGSVPVFIRALAFGDRIALIDKYGHHTYRELYDRSLCLAQEICRLQGCKVGDLQEERVSFLCSNDVSYVVAQWASWMSGGVAVPLYWKHPEAQLEYFIQDSRSSLVVVGQEYLERLSPLAQRLGVPLLPLTPAVYHGATEKPTEQPVEESGWRDRGAMIFYTSGTTGRPKGALSTHRNLAAVVTGLVHSWAWTKNDVILHVLPLHHVHGVVNKLLCPLWVGATCVMLPEFSAQQVWEKFLSSEAPQITVFMAVPTVYSKLLDYYDKHFTQPHVQDFVRAVCKERIRLMVSGSAALPVPLLEKWRSATGHTLLERYGMTEIGMALSNPLT-EARVPGSVGTPLPGVEVRIISENPQK-GSPYIIHAEGNERGTKVTPGFEEKEGELLVRGPSVFREYWDKPEETKSAFTSDGWFRTGDTAVFKDARYWIRGRTSVDIIKTGGYKVSALEIERHLLAHPSITDVAVIGVPDMTWGQRVTAVVALQEGHSLSHGDLKEWARGVLAPYAVPSELLLVEEIPRNQMGKVNKKELLKQLYPSGQRSQPGQG", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q4G176-1", "uniprot_id": "ACSF3_HUMAN", "id": "Q4G176-1", "name": "Malonate--CoA ligase ACSF3, mitochondrial", "aln": "MLPHVVLTFRR--LGCA-LASCR------LAPARHRGSGLLHTAPVARSDRSAPVFTRALAFGDRIALVDQHGRHTYRELYSRSLRLSQEICRLCGCVGGDLREERVSFLCANDASYVVAQWASWMSGGVAVPLYRKHPAAQLEYVICDSQSSVVLASQEYLELLSPVVRKLGVPLLPLTPAIYTGAVEEPAEVPVPEQGWRNKGAMIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAWTKDDVILHVLPLHHVHGVVNALLCPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQDFLRAVCEEKIRLMVSGSAALPLPVLEKWKNITGHTLLERYGMTEIGMALSGPLTTAVRLPGSVGTPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGELLVRGPSVFREYWNKPEETKSAFTLDGWFKTGDTVVFKDGQYWIRGRTSVDIIKTGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTWGQRVTAVVTLREGHSLSHRELKEWARNVLAPYAVPSELVLVEEIPRNQMGKIDKKALIRHFHPS---------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A2R8QFY7-1", "uniprot_id": "A0A2R8QFY7_DANRE", "id": "A0A2R8QFY7-1", "name": "", "aln": "MLSYHAVFVRSRSLTCSYLRGSRRALEWLLGNVQHRTFTFSDLINSPAGAKVAPVFSRAPAYGDKVAIMDHSGSHTYHSLYKNSKILAGHITKALTCQSGDLQGKRISFLCANDASYTVAQWASWMCGGIAVPLYRKHPLSELEYVISDSQSSLLVAGQSFVDTLEPLAQKLGLPCLKL-PATSSQFEDTQTLPEDMISDWAERPAMLIYTSGTTGRPKGVLHTHSSLQAMVQGLVSEWAWHKDDVILHTLPLHHVHGIVNKLMCPLWVGATCIMLPDFSAQKVWEQLICSKSPMVNVFMAVPTIYSKLIEYYDQHFTQPQVQDFIRAVCKERIRLMVSGSAALPQPVLERWAEITDHVLLERYGMTEIGMALSNSYK-GPRVPGAVGVPLPGVEVRIMMN-------SSIVIAEGTSKGTQVKAGLEGKEGELLVRGSSVFQKYWNKPQETEESFTEDRWFKTGDTALYRDGVYWIMGRTSVDIIKSGGYKISALDVERHLLAHPDITDVAVIGAPDATWGQKVTAVVQMRKGKTMILSDLKAWAREHMASYSIPTGLILVEDMPRNQMGKVNKKDLLRQFFPGGSQ------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* .: .: .* * : * ..: * :** : . .*** ** *:**::*::*: * ***:.**..* *: .* : * ***: :*:****:**.**.********.**:***** *** ::***.* **:**:::..*.::: *.*:.::**:* * * ** : : ..* :: **::***********.* ** .: *:* *** .*** *:*****.********:** *:*********:*:*:**.*:***:::.*::* :.*******:*:**::***:*****:.***:****:*:************ *:**:* . *.*.***************.. . *:**:**.*****:***: : . : *** .:**:*..*:* *********.***::**:**:**:.:** * **:****.:::*. *** *********:****:***::* ******.********.** ****:***** :::*::: :** *** :*.*::*: *:***::*******::** *::::.*. ", "identical_positions": 313, "similar_positions": 159, "identity": "52.69%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121029-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "O43543-1", "uniprot_id": "XRCC2_HUMAN", "id": "O43543-1", "name": "DNA repair protein XRCC2", "aln": "MCSAFHRAESG------------TELLARLEGRSSLKEIEPNLFADEDSPVHGDILEFHGPEGTGKTEMLYHLTARCILPKSEGGLEVEVLFIDTDYHFDMLRLVTILEHRLSQSS--------EEIIKYCLGRFFLVYCSSSTHLLLTLYSLESMFCSHPSLCLLILDSLSAFYWIDRVNGGESVNLQESTLRKCSQCLEKLVNDYRLVLFATTQTIMQ-----------KASSSSEEPSHASRRLCDVDIDYRPYLCKAWQQLVKHRMFFSKQDDSQSSN-QFSLVSRCLKSNSLKKHFFIIGESGVEFC---", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9CX47-1", "uniprot_id": "XRCC2_MOUSE", "id": "Q9CX47-1", "name": "DNA repair protein XRCC2", "aln": "MCSDFRRAESG------------TELLARLEGRSSLKELEPNLFADEDSPVHGDIFEFHGPEGTGKTEMLYHLTARCILPKSEGGLQIEVLFIDTDYHFDMLRLVTVLEHRLSQSS--------EEAMKLCLARLFLAYCSSSMQLLLTLHSLEALLCSRPSLCLLIVDSLSSFYWIDRVSGGESVALQESTLQKCSQLLERLVTEYRLLLFATTQSLMQ-----------KGSDSADGPS-SSKHPCDGDMGYRAYLCKAWQRVVKHRVIFSRDDEAKSS--RFSLVSRHLKSNSLKKHSFMVRESGVEFC---", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0AB13A3Z0-1", "uniprot_id": "A0AB13A3Z0_DANRE", "id": "A0AB13A3Z0-1", "name": "", "aln": "MLDPLALPHHGPQGLPVSENTNPTMLVSRLEGRQSLKDIEPNIFPADDGPGQGDVVEFHGMEGSGKTETLYHLITRCITPTHSGGLEVGVVFIDTDYHFDMLRFVSILEGRLAEDSKTGSENEAEETVRSCLCRLSVVHCNSSVQLLLTLHYLENTFSSQPTLGLLVIDSISAFYWTDRFNGGESASCQEANLRKCAELLDRLRRNYGIVIFATTHAIMRNFGSDLGVSDVHGSSSSSSSRRWRSADCASDFD-RPYLCRAWQRIVTHRVLFTKSHAPKDHKQIFSTACTSILTKGVKKCSFCVVEDGIKFICDK", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* . : .. * * *::*****.***::***:*. :*.* :**:.**** **:**** **** :*** *. .***:: *:************:*::** **::.* ** :: ** *: :.:*.** :*****: ** :.*:*:* **::**:*:*** **..****. **:.*:**:: *::* :* :::****:::*: :.*.*:. . * *:. *.***:***::*.**::*::.. .:. ** .. : ::.:** * : *.*::* ", "identical_positions": 128, "similar_positions": 97, "identity": "40.63%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121030-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "F8WFN8-1", "uniprot_id": "F8WFN8_RAT", "id": "F8WFN8-1", "name": "", "aln": "METAYLKKCFGNTLTQALAEVARVQPNDPIEYLAHWLYHHRNITKAEEKKKQEELQLQEVHDSNSKEAKATATLKEGSYQIKQKCEKRHQELPSTSVSSDQTPALQEDLALREEKS-TRQEAPPGVSN--VITKTPQSAIPS------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q96IM9-1", "uniprot_id": "DYDC2_HUMAN", "id": "Q96IM9-1", "name": "DPY30 domain-containing protein 2", "aln": "METNYLKRCFGNCLAQALAEVAKVRPSDPIEYLAHWLYHYRKTAKAKEENREKKIHLQEEYDSSLKEMEMTEMLKQEEYQIQQNCEKCHKELTSETVSTKKTIFMQEDTNPLEKEA-LKQEFLPGTSS--LIPGMPQQVPPSESAGQIDQNFKMPQEINYKEAFQHEVAHEMPPGSKSPF----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8I6ADI0-1", "uniprot_id": "A0A8I6ADI0_RAT", "id": "A0A8I6ADI0-1", "name": "DPY30 domain-containing protein 1", "aln": "MESRYLQQCLGTCLTQGLAEVARVRPLDPIEYLALWIYKYKENESMEQLRQKELIALEHERELAMMEQEMMDRLKAEELLFQQQ-LAFQLELEMQEKEKQKTEDFKTEQEKSTKDT-MSTESISKGEE--AMPSEESMMDSGKTLAEISDRYGAPNLSRVEELDEPMLSDILSNEPGVHLLARLSGR---------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q9D9T0-1", "uniprot_id": "DYDC1_MOUSE", "id": "Q9D9T0-1", "name": "DPY30 domain-containing protein 1", "aln": "MESRYLQKCLGTCLTQGLTEVARVRPLDPIEYLAFWLYKHKENMNMEQMRQREMITLEHERELAMMEQEMLERLKAEELLFQQQ-LAFQLELEMQQKEKQKSEDFETGQEKSFKSM-MSMESTARGEEQEPMQAEELVMDSGKTLAEISDRYGAPNLSRVEELDEPMLSDNGVSAPP-------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8WWB3-1", "uniprot_id": "DYDC1_HUMAN", "id": "Q8WWB3-1", "name": "DPY30 domain-containing protein 1", "aln": "MESIYLQKHLGACLTQGLAEVARVRPVDPIEYLALWIYKYKENVTMEQLRQKEMAKLERERELALMEQEMMERLKAEELLLQQQQLALQLELEMQEKERQRIQELQRAQEQLGKEMRMNMENLVRNED--ILHSEEATLDSGKTLAEISDRYGAPNLSRVEELDEPMFSDIALNIDQDL-----------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A0G2KNT1-1", "uniprot_id": "A0A0G2KNT1_DANRE", "id": "A0A0G2KNT1-1", "name": "", "aln": "MDSAYVNRCLGVCLAEGLAELIEHRPQEPIEYLALWIRSYREKQRLQEQRSAFESRLKEEKQRLHDESLHQQLLQEEQKQIRAAQEEIKHTEEPQPESAEQSKATPADSTSSQAEEQVESVEAPADQP--ESDTVKEQTDPALNEEESGETAGDEEQSAEIQNTEQSLSQEDLGDTPKENNEADVQSEENKPELEQTEEEADEGQIEAEEKVTHTAETEDTAAVEEAGQAGEQDEEED", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*:: *::: :* *::.*:*: . :* :****** *: ::: :: . *:. : * *: . :: : . .: . . .. ", "identical_positions": 17, "similar_positions": 36, "identity": "7.14%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121030-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q96M53-1", "uniprot_id": "TBATA_HUMAN", "id": "Q96M53-1", "name": "Protein TBATA", "aln": "MATDV-QLADYPL-------------------------------------MSPKAELKLEKKSGRKPRSPRDSGPQKELVIPGIVDFERIRRALRTPKPQ----TPGTYCFGRLSHHSFFSRHHPHPQHVTHIQ----------------------------------DLTGKPVCVVRDFP--APLPESTVFSGCQMGIP-----TISVPIGDPQSNRNPQLS-SEAWKKELKELASRVAFLTKEDELKKKEKEQ----KEEPLREQGAKYSAETGRLIPASTRAVGRRRSHQGQQSQSSSRHEGVQAFLLQDQELL--------------VLELLCRILETDLLSAIQFWLLYAPPKEKDLALG-----------------LLQTAVAQLLPQPLVSIPTEKLLS----QLPEVHEPP--------QEKQEPPCSQS-------------------------------------------------------------------------------------PKKTKISPFTKSEKPEYIGEAQVLQMHSSQNT-----EKKTSKPRAES----------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q7TSD4-1", "uniprot_id": "TBATA_MOUSE", "id": "Q7TSD4-1", "name": "Protein TBATA", "aln": "MTTEVNQLSEHPL-------------------------------------VSPKAEPQPETKPENLPRSHGDVGLQKETVVPGIVDFELIHEELKTTKPQTSQPTPSAYRFGRLSHHSFFSRHHPQPQRVTHIQVTGREDLEHSLPLTTSFQLLQAPGVQPMDLTPSADIAGKPVCVVRDEFSLSALTQPTFLSRCLMGMP-----TISVPIGDPQSNRNPQLSTSDTWRKKLKDLASRVTVFTKEIQPKPDEQKEEPPLREPPPREQGAKYSAETGRLIPASSQALTRR-NRQGQRVHPSSKDGGVQASILQDQELL--------------ILELLCQILQTDSLRAIQFWLLYAPSKEKDLALG-----------------LLQTAVAQLIPQPLSSIPAEKLWN----HLQELQEP---------QETQEAAYSPS-------------------------------------------------------------------------------------LKKTRSPPLPKTDKPEYIGKAQVLLVHPSEDP-----EEKTTK--AES----------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8I5YC32-1", "uniprot_id": "A0A8I5YC32_RAT", "id": "A0A8I5YC32-1", "name": "", "aln": "MEQATQGAAQQRLPRNRGRRTWLSIFPAHLHSTKGPPSSQGQQEKEVQKATSPKTEPQPEKKPEQVPRSHGDVGFQKEPVVPGIVDFELIHEDLKTTKPPTLQPTPGAYRFGRLSHHSFFSRHHPQAQRVTHIQ----------------------------------DIAGKPICMVRDEFSLAALTQPSFLTPCVMGMP-----TVSVPIGDPQSNRKPRLSTSATWRKNLKDLASRVTFFTKEIASTTNEQKDEPPMKDPSPREQGAKYSAETGRLIPAYSHALTRR-NRQAQRGHTSGKGGGVQASILQDQELLGGLTAPGVKFSGPVGRGPRAGFLGLHLLPPVPPPPLHSYRQHRQPGLGSPP---------STSKKQTEHILPLLDPRPQKKPPAKKAARDGDSQLLHWMEPLTKHLAETTQSGQQAANSESPTSWQTFPDSWSSRVGRPLGYPKSPPKTSQHAGLDPGASLSDSTNRFSKGYPVLAALRSAKRKRFGFGASADGLGSAHPPASPLHPSREAVAPTSRASRPSSRDTTGNLQSIPEEDENTTSIQDRQTRVHGQSPSPPSTSDREPRGENDQAQGLKLRSIAESTETSE", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "A0A8M6Z3N1-1", "uniprot_id": "A0A8M6Z3N1_DANRE", "id": "A0A8M6Z3N1-1", "name": "", "aln": "----------------------------------------------------------------------MDESEQQANVSVSRADLSSVQRESAGSRAT----TRGSLRFGTLSHHSFFSRHNPHPHRVRHMQG----------------------------------LNGKPVCMVNDDWFAFTPLCPHPLIKSQVSVSGSRSSAFFTPEISSDRSGPRAALISESWREELKDLATKITLSAAAETQHDKREPQKHADDEAPRRK--TQYSSQSGRIIPSSSWGGKKR-------SRTSHRRMTTHTHMLEGLELK--------------VLELLCQILQTDSLSMVQQWLLLASDKEKELVQG-----------------LLKQAVSDCSSLSLHTSADPLNTEH------LLLEPAG------RAHRSSLRRS-----------------------------------------------------------------------------------------------ETLPEEPERIGEAEVLTLYPENT---------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "A0A0G2K1J3-1", "uniprot_id": "A0A0G2K1J3_RAT", "id": "A0A0G2K1J3-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------MTERNKGCFIVRHTPHPRRVCHIQG----------------------------------LNNVPICTVKDDLPIRMLCCPRQLSPSQKNET-----------TLAKVSNPPRSASPESLSIRGVSPAKNKVPERPHSEPFRKINHNFRTSRDNPLVNKKDEYKPKK-PLVASRMCSGAASPSSDVMNTRINRNENTVCIPNYLDQEIK--------------ILLKLCDILHTDSLTEVLDWLLQASNKEKEWLSALIHSELSEINLLTRHRVNTPEPAAESRKSPTSVTPTTKLLQNSHAKLKALHESR--------EEHQPLRMTSQ-------------------------------------------------------------------------------------GSEGNKMASKGAETPLFIRRNKKLPVTEYFNNPKSPFKPNTQESRSARPMSVRSVQGYSPQRALYPLTHGREK---------", "tax_id": 10116, "tax_name": "Rat" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : .: .*: ** *:.::* *:* : . *:* *.* . : . . . .. . . : . . *.. . . : : : . : :*..:. ::.: . : . . . . *: . :* . * : * : :.:: . . . . *. . : .. * * ", "identical_positions": 20, "similar_positions": 69, "identity": "3.3%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121030-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q6W5G4-1", "uniprot_id": "PLPR2_RAT", "id": "Q6W5G4-1", "name": "Phospholipid phosphatase-related protein type 2", "aln": "MAG----GRPHLKRSFSIIPCFVFVESVLLGIVVLLAYRLEFTDTFPVHTQGFFCYDSAYAKPYPGPEAASRAPPALIYALVTAGPTLTILLGELARAFFPAPPSSSPVSGESTIVSGACCRFSPPLRRLVRFLGVYSFGLFTTTIFANAGQVVTGNPTPHFLSVCRPNYTALGCPPPSPDRPGPDRFVTDQSACAGSPSLVAAARRAFPCKDAALCAYAVTYTAMYVTLVFRVKGSRLVKPSLCLALLCPAFLVGVVRVAEYRNHWSDVLAGFLTGAAIATFLVTCVVHNFQSRPHSGRRLSP--------------WEDLSQAPTMDSPLEKNPR----PAGRIRHRHGSPHP------SRRTVPAVAT", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8VCY8-1", "uniprot_id": "PLPR2_MOUSE", "id": "Q8VCY8-1", "name": "Phospholipid phosphatase-related protein type 2", "aln": "MAG----GRPHLKRSFSIIPCFVFVESVLLGIVVLLAYRLEFTDTFPVHTQGFFCYDSAYAKPYPGPEAASRAPPALIYALVTAGPTLTILLGELARAFFPAPPSSSPVSGESTIVSGACCRFSPPLRRLVRFLGVYSFGLFTTTIFANAGQVVTGNPTPHFLSVCRPNYTALGCPPPSPDRPGPDRFVTDQSACAGSPSLVAAARRAFPCKDAALCAYAVTYTAMYVTLVFRVKGSRLVKPSLCLALLCPAFLVGVVRVAEYRNHWSDVLAGFLTGAAIATFLVTCVVHNFQSRPHSGRRLSP--------------WEDLSQAPTMDSPLEKNPR----PAGRIRHRHGSPHP------SRRTVPAVAT", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96GM1-1", "uniprot_id": "PLPR2_HUMAN", "id": "Q96GM1-1", "name": "Phospholipid phosphatase-related protein type 2", "aln": "MAG----GRPHLKRSFSIIPCFVFVESVLLGIVILLAYRLEFTDTFPVHTQGFFCYDSTYAKPYPGPEAASRVPPALVYALVTAGPTLTILLGELARAFFPAPPSAVPVIGESTIVSGACCRFSPPVRRLVRFLGVYSFGLFTTTIFANAGQVVTGNPTPHFLSVCRPNYTALGCLPPSPDRPGPDRFVTDQGACAGSPSLVAAARRAFPCKDAALCAYAVTYTAMYVTLVFRVKGSRLVKPSLCLALLCPAFLVGVVRVAEYRNHWSDVLAGFLTGAAIATFLVTCVVHNFQSRPPSGRRLSP--------------WEDLGQAPTMDSPLEKNPR----SAGRIRHRHGSPHP------SRRTAPAVAT", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2BD34-1", "uniprot_id": "A0A8M2BD34_DANRE", "id": "A0A8M2BD34-1", "name": "Phospholipid phosphatase-related protein type 5", "aln": "MDRRRFVGRGAVKRSKYIVPCFLFVELVIMAGTVLLAYYFEYTDTFPVHIQGFFCYDKTFSKPYPGPEDDSKAPPVLVYSLVTAIPTVTILLGELA-SFFTKPEASQ----EKTIVTADCCYFNPLLRRIVRFLGVYSFGLFTTTIFANAGQVVTGNQTPHFLSTCRPNYTALGCHSP-------MQYITERRACTGNPYLIASARKSFPSKDSALSMYSAVYTVMYVTLVWRTKGTRLTKPTLCLTLLSLAVLVGIVRVAEYRNHWSDVLAGYLTGGAIAAFLVTCVINNFQQTQSHVPRLPPPVLPPPPPRPEPSLNMPMVAMPCVESPLENRFQGFYTQASHDHQPYLAPVPPDVLIHSRRSISSAV-", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* ** :*** *:***:*** *::. .:**** :*:******* *******.:::******* *:.**.*:*:**** **:******** :**. * :: *.***:. ** *.* :**:*************************** ******.********** .* :::*:: **:*.* *:*:**::**.**:**. *:..**.******:*.**:**.**:***:**. *.***:****************:***.***:******::***. **.* : * ::****:. : *.: :: : :* * ***: .:.. ", "identical_positions": 201, "similar_positions": 83, "identity": "54.18%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121030-8", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P82987-1", "uniprot_id": "ATL3_HUMAN", "id": "P82987-1", "name": "ADAMTS-like protein 3", "aln": "------------MASWTSPWWVLIGMVFMHSPLPQTTAEKSPGAYFLPEFALSPQGSFLEDTTGEQFLTYRYDDQTSRNTRSDEDKDGNWDAWGDWSDCSRTCGGGASYSLRRCLTGRNCEGQNIRYKTCSNHDCPPDAEDFRAQQCSAYNDVQYQGHYYEWLPRYNDPAAPCALKCHAQGQNLVVELAPKVLDGTRCNTDSLDMCISGICQAVGCDRQLGSNAKEDNCGVCAGDGSTCRLVRGQSKSHVSPEKREENVIAVPLGSRSVRITVKGPAHLFIESKTLQGSKGEHSFNSPGVFLVENTTVEFQRGSERQTFKIPGPLMADFIFKTRYTAAKDSVVQFFFYQPISHQWRQTDFFPCTVTCGGGYQLNSAECVDIRLKRVVPDHYCHYYPENVKPKPKLKECSMDPCPSSDGFKEIMPYDHFQPLPRWEHNPWTACSVSCGGGIQRRSFVCVEESMHGEILQVEEWKCMYAPKPKVMQTCNLFDCPKWIAMEWSQCTVTCGRGLRYRVVLCINHRGEHVGGCNPQLKLHIKEECVIPIPCYKPKEKSPVEAKLPWLKQAQELEETRIATEEPTFIPEPWSACSTTCGPGVQVREVKCRVLLTFTQTETELPEEECEGPKLPTERPCLLEACDESPASRELDIPLPE-DSETTYDWEYAGFTPCTATCVGGHQEAIAVCLHIQTQQTVNDSLCDMVHRPPAMSQACNTEPCPPRWHVGSWGPCSATCGVGIQTRDVYCLHPGETP----APPEECRDEKPHALQACNQFDCPPGWHIEEWQQCSRTCGGGTQNRRVTCRQLLTDGSFLNLSDELCQGPKASSHKSCARTDCP-PHLAVGDWSKCSVSCGVGIQRRKQVCQRLAAKGRRIPLSEMMCRDLPGLPLVRSCQMPECSKIKSEMKTKLGEQGPQILSVQRVYIQTREEKRINLTIGSRAYLLPNTSVIIKCPVRRFQKSLIQWEKDGRCLQNSKRLGITKSGSLKIHGLAAPDIGVYRCIAGSAQETVVLKLIGTDNRLIARPALREPMREYPGMDHSEANSLGVTWHKMRQMWNNKNDLYLDDDHISNQPFLRALLGHCSNSAGSTNSWELKNKQFEAAVKQGAYSMDTAQFDELIRNMSQLMETGEVSDDLASQLIYQLVAELAKAQPTHMQWRGIQEETPPAAQLRGETGSVSQSSHAKNSGKLTFKPKGPVLMRQSQPPSISFNKTINSRIGNTVYITKRTEVINILCDLITPS-EATYTWTKDGTLLQPSVKIILDGTG-KIQIQNPTRKEQGIYECSVANHLGSDVESSSVLYAEAPVILSVERNITKPEHNHLSVVVGGIVEAALGANVTIRCPVKGVPQPNITWLKRGGSLSGNVSLLFNGSLLLQNVSLENEGTYVCIATNALGKAVATSVLHLLERRWPESRIVFLQGHKKYILQATNTRTNSNDPTGEPP------------------------------------------------------------------------PQEPFWEPGNWSHCSATCGHLGARIQRPQCVMANGQEVSEALCDHLQKPLAGFEPCNIRDCPARWFTSVWSQCSVSCGEGYHSRQVTCKRTKANGTVQVVSPRACAPKDRPLGRKPCFGHPCVQ--WEPGNRCPGRCMGRAVRMQQRHTACQ--HNSSDSNCDDRKRPTLRRNCTSGACDVCWHTGPWKPCTAACGRGFQSRKVDCIHTRSCKPVAKRHCVQKKKPISWRHCLGPSCDRDCTDTTHYCMFVKHLNLCSLDRYKQRCCQSCQEG----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "G3UXC7-1", "uniprot_id": "G3UXC7_MOUSE", "id": "G3UXC7-1", "name": "", "aln": "MAVRETPMILDPMASWTGSWWLLTRMIFTVSGLLQATAEKSPGAYFLPEFALSPQGSFLEDTTGEQFLTYRYDDQTSRNAHSEEDKDGNWDAWGDWSDCSRTCGGGASYSLRRCLTGRNCEGQNIRYKTCSNHDCPADAEDFRAQQCSAYNDVQYQGHYYEWIPLYNDPAAPCALKCHARGQSLVVELAPKVLDGTRCNADSLDMCISGICQIVGCDRQLGSNAKEDNCGVCAGDGSTCRLVRGQTKMHLSPEKKEENVIAVPLGSRSVRITVKGPALIFIESKTLQGSRGEHSFNSPGVFTVENTTIEFQKGADRQTFKIAGPLMADFIFKTRYTVAKGSVVQFFFYQPISHQWRQTDFFPCTVTCGGGYQLNSAECMDIRLKRVVPDHYCHYYPENVKPKPKLKECSMDPCPSSDGFKEIMPYDHFQPLPRWEHNPWTACSVSCGGGIQRRSFVCVEESMHAEILQVEEWKCMYAPKPTVMQACNLFDCPKWVAMEWSQCTVTCGRGLRYRVVLCINHRGQHVGGCNPQMKLHIKEECVIPIPCYKPREKSPVEAKLPWLKQAQELEETRIATEEPKFIPEPWSACSTTCGPGIQVREVRCRVLLTFTQTEAELPEEECEGPKPPTDRPCLRQACDQSPVSRELGGRLQEKDSEMTYDWEYAGFTPCTATCLGGHQEAIAVCLHTQTHQTVNDSLCDTVHRPPPMSQACNMEPCPPRWHMGSWGACSATCGVGIQTRDVYCLHPEEFP----APPEECREEKPHALRACNQFDCPPSWHIEEWQQCSRTCGGGTQNRRVTCRQLLTDGSFLNLSDELCQGPKASSHKSCARTDCP-PQLAAGDWSKCSVTCGVGFQRRKQVCQKLTAKGRRVSVAETLCRDLPGLPLVRPCQMPICSKAKLGTKTKLGERGPQILGVRRVYIQTREEKRINLTVGSRAYLLLNTSVIIKCPVRRFQKSLIQWEKDGHCLKNSKQLGITKSGSLKIHSLAAPDIGVYRCIAGSAQETVVLKLIGTDNRLIAHPSLREHVRGHPGVDHNEANSLGATWHKMRQMWNNKNDLYLHGGEMNKQPFLRALFGPCRTSEGNDNSWEFKNKQFEAAMKQGAYSMDTAQFDELIRNMSQLMEMGEASDDLASQMIYQLVAELAKAQPTPVQWRGIREEVAPEAQLRGKTERVPKNPTVKNSGKLTFKPKGPVLMRQILPPSVSFNKTINARIGNTVYITKSTEIINILCSLITPSKEATYTWTKDGALLQPSVKIILDETG-KMQIRNPTRKEQGIYECSVASHLGSDVESSLVLYAEAPVILSIERNVTKPEHNHLSVVVGGTVEAALQANVTIHCPVKGVPQPNVTWLKTGGSLSDNVSLLFNGSLLLQSASLENEGTYICTATNALGKAVATSGLRLLERREPGGKAAFPKVQKTRVLQAPRSRINSNNLTGKSL------------------------------------------------------------------------PQEHFWEPGNWTHCSATCGPLGFRLQRPRCVMASGQEVSEALCGPHRKPLAGFQSCNIRDCPARWFTSMWSECSASCGEGFHSRQVTCKQTKANGTVQVVSPRACAPKDRPLGRKPCSIRPCVQQAIDPGNQCPGRCMGHATRMQHHHTACS--HNSSSSDCEDGRRPAFGRNCTLGPCEACWRVGPWKPCTAVCGRGFQSRKVDCIHTGSCKIVADRYCVQVK-PAAWRHCLGPSCDRNCTDTTHYCMFVKHLNLCSLAVYRQRCCQSCQEG----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B5R1-1", "uniprot_id": "A0ACD6B5R1_DANRE", "id": "A0ACD6B5R1-1", "name": "", "aln": "------------MELWILAVCRISLMLTLMSSTGQGVASQTQSAYFLPEFALSPQGSFLEDTTGEQYLTYRYDDQSSRTTRSDEERDTGWDAWGTWSDCSRTCGGGASYSLRRCLNGGNCEGRNIRYRTCSNTDCPLESGDFRAQQCSAHNDIKYQGQTYEWIPVTYDPISPCALRCQARGKGQVVELAPKVLDGTRCKADSLDMCISGICQEVGCDRQLGSNAKEDNCGVCAGDGSTCRLIRGQALPHVSPEEPIKTVIEVPMGSRGLRITAKGPDMIVIEAHGQNSRREEVHFSSSGSHSLGNNTVEFQRGAERQTLRCYGPLTADFTVKVKYAGPKDTVIQFMFYQPIRYQWRETDFFPCSVTCGGGYQLNSADCVDIRYNRSVAEHLCHSFPENTKPTPKLKECNMEPCPESDGFKEVMPYDHFQPLPRWEQNPWTSCSVSCGGGSQERSIVCVEEDVHGQIVQVEDWKCTHSPRPISKQNCNTFDCPQWMAMEWSQCTVTCGPGLRYRVVLCVDYNGQHAGGCNPHLKPHIKEDCLVPIACHKPRENQPVEAKLPWLKQAQELEETKVALEDPTFVPEPWSSCSVSCGLGIQRRQVKCKVLLSFTQAEVELPDEECHEEKPSSQRSCDSGPCLAAPDSRWP-LRTPEGPNQHGYAWEYIGFTACSASCAVGKQMAVVRCVNTLKKEIVDDLLCNGSKAPVSLLRICNPQPCPPRWEVSVWNLCSVSCGVGLQTRSVSCVRSVAGNRTESLSSKDCVGKRPNELQACNQVACPPSWEAEEWQQCSHSCGRGSQWRKVYCKQRLATGSYRRLKDEDCTGPKPDVHRICTNADCLLPRLEGGEWSKCSVTCGKGVQRREPVCRRQTASGQLVTLDRTSCSDLPLPPLIRSCRMSPCNKHKHSKK-----RCPQVIGLKRIYIQNRPEKRLSFTVGGRAYLLPKTTVIIKCPVRHFPKAQIRWEKDGDELTSSKRLSITKSGALRIYNLEAEDIGVYRCWANQDSDTFILKLIGYNNRLLDHPSLGKERRGNFHPYLNKEG--GFVSSKCNEGFTNGNKASKSS-WMQKNEFYRDDDGHPKEMLWDTLALGNYALASSTRSHTGAFVLEPAQFEELVKNISQLAESGDVTDEMASQLIGKLLEDLAAAG----QGQVPIEESTTVDNYLDRTSNTSELFGTEVS------KIAAIVRQKHHGSVMSFQRDLRIHVGRTAYLTNATHSLTLLCPSKGSP-KPKLSWTKDGAPLQDINRVSWDSSGGELHISSPGASDVGIYRCTSTNELGSDSETTQVLLAESPTIAASRRNTSDLKSTSLKVVVGGVIRVRSGANLTLECPVKGVPHPAVSWHRKEGPLDARASPLLSGSLLLTNLTQQDEGTYSCIAANTIGKSAASSRISVEGAVGEPDLQSSKQMNRKRVLMASQVGTSAYVRPGDTLRIGCPVVPGHRRPIRWRFENRTLAAAAGGLYRLLVGGRVLEINTHTGSFSGRYQCQTQTNNQQQLTAWIHLLSQEFEWRLGDWSTCSSSCGNRGTQMKKIKCVSSEGRESSHAACHYLPKPSSQTRPCNLLHCPPSWVSTVWSRCSSSCGRGFRERRVSCQQVEASGSVKVLPSSECEGSPRPEDRQECSSQACVEWISGPWGKCAGRCLGPAMATQTRTVSCRLFSNSTSKTCDPKERPSAVRNCSSEMCDVHWKVFPWRTCTVACGSGFQSRRVECVHRQNKKTLPDQHCAWQRRPVTWQHCNITSCGSECKDRTHYCPAVKRLKLCSVDLYRQRCCQTCLQDTAAT", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * . : *: * * .*.:: .***********************:********:**.::*:*::* .***** ********************.* ****:****:**** *** :: *********:**::***: ***:* ** :****:*:*:*:. **************::************ ****************************:***: *:***: :.** **:***.:***.*** :.**:: :. : * *.*.* . : *.*:***:*::***:: *** *** .*.:*: .*.:*:**:***** :***:******:************:*:*** :* *.:* ** :***.**.******.*:***.******:*************:****:******** *.**:*****.:*.:*:***:*** ::*:* * ** ****:*:************ *********:::.*:*.*****::* ****:*::**.*:**:*:.******************::* *:*.*:*****:**.:** *:* *:*:*:***:***:*.***:***. * .::*.* .* :* ** * .: * *** ***.*:*:* *:* *:. *:: .:: *:* **: : * .: : ** :******.:. *. **.:****:***.* *::. ..::* ::*: *:****. ***.*. *******::** *:* *:* *:* *: **: .*.** * ***.. *: *:.:** *:* *:******:** *.***: **:: :*.*: :.: . * *** **:*.*:*. *.* * * : **::.::*:***.* ***:.:*:*.***** :*:********:* *: *:***** * .**:*.*****:*:*:.* * ******* *.. .:*.:***** :***: :*:* : * .: . * . * .: :.* *. . :.:: * * * . : .: : **: ::.***:**::*:*** * *:.:*::***:* :*: :** * * : ** .. : ..* ..: .: * ..:: :: . :**:: :. ::*.*.*:*: *. :.:** .. :.. :*****: ** :: * :* :::* .* .: ***.*: :..**** *:: ** **:*.* : .** :. : . *.***** :.. **:*:.*******:* ::* : *.*. ..* *:.***** . : ::**** * *:*::**:.*:* : : . : ::. :* *.. .: .*.. .** *. *:*: **::** * :::: :** :.*:* *.* * ** : ..**: .**. *.:::**.** ***.*::.*:*:*::.:*.*:*:*:.. * . ** .*: * :.**: * .:*.***:* * * : .:* **:.. *: .**: ***: *:. *:. **:.**..** *****:*:*:* . * :..::*. : * :*:** .**. :*.* **** **:*:***: *:*****:* :. ", "identical_positions": 811, "similar_positions": 489, "identity": "45.28%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121030-9", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0ABK0L3E1-1", "uniprot_id": "A0ABK0L3E1_RAT", "id": "A0ABK0L3E1-1", "name": "", "aln": "MVNSLLFGEMALAFGCPPGGGG--CASGGGGGG-AGPGPSPVTAALRDDLGSNIHLLKGLNVRFRCFLAKVHELERRNRLLEKQLEQQQSERDRRLRYKTFSREQAVQTGPELLRPPAAGGGQAL--GAATGVNANAVALGGLPPGGGSHPQHYGRLPGTIWSYTQVRRTGGGGVETVQGPGVSWVHPDGVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEELAKCMNLQTMVDTLQEAAQEAEAIQEEMNEKIERLKAELVVFKGLMSDP--------------------MTDLDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNSEDVSKIFQ---------VVPKKKDRKVASDDDISEQDGEVNRFSDEEVGSMNITDEMKRMFNQL----------RETFDFDDDCDSLTWEENEDTLLLWEDFTN----CNPTIDLQG-------EQEENLGNLIHETESFFKTRDKEYQETIGQIELELATAKSDMNRHLHEYMEMCSMKRGLDVQMETCRRLIKGSADRNSPSPSSVASSDSGSTDEIQDDLEREADVEPMVS", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8R2V2-1", "uniprot_id": "IFFO2_MOUSE", "id": "Q8R2V2-1", "name": "Intermediate filament family orphan 2", "aln": "MVNSLLFGEMALAFGCPPGGGG--CAGGGGGGG-AGPGPSPVTAALRDDLGSNIHLLKGLNVRFRCFLAKVHELERRNRLLEKQLEQQQSERDRRLRYKTFSREQAVQTGPELLRPSAAGSGQAL--GAATGVNANAVALGGLPPGGGSHPQHYGRLPGTIWSYTQVRRTGGGGVETVQGPGVSWVHPDGVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEELAKRMNLQTMVDTLQEAAQEAEAIQEEMNEKIERLKAELVVFKGLMSDP--------------------MTDLDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNSEDVSKIFQ---------VVPKKKDRKVASDEDISEQDGEVNRFSDEEVGSMNITDEMKRMFNQL----------RETFDFDDDCDSLTWEENEDTLLLWEDFTN----CNPTIDLQG-------EQEENLGNLIHETESFFKTRDKEYQETIGQIELELATAKSDMNRHLHEYMEMCSMKRGLDVQMETCRRLIKGSADRNSPSPSSVASSDSGSTDEIQEDLEREADVEPMVS", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q5TF58-1", "uniprot_id": "IFFO2_HUMAN", "id": "Q5TF58-1", "name": "Intermediate filament family orphan 2", "aln": "MVNSLLFGEMALAFGCPPGGGGGGCPGGGGGGGGAGPGPSPVTAALRDDLGSNIHLLKGLNVRFRCFLAKVHELERRNRLLEKQLEQQQSERERRLRYKTFSREQAVQTGPELLRPPAPGGGHGLSSGAAAGANANAVALGGLPPGGGSHPQHYGRLPGTIWSYTQVRRTGGGGVETVQGPGVSWVHPDGVGVQIDTITPEIRALYNVLAKVKRERDEYKRRWEEELAKRMNLQTMVDTLQEAAQEADAIQEEMNEKIERLKAELVVFKGLMSDP--------------------MTDLDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNSEDVSKIFQ---------VVPKKKERKVASDDDISEQDGEVNRFSDDEVGSMNITDEMKRMFNQL----------RETFDFDDDCDSLTWEENEDTLLLWEDFTN----CNPTIDLQG-------EQEENLGNLIHETESFFKTRDKEYQETIGQIELELATAKSDMNRHLHEYMEMCSMKRGLDVQMETCRRLIKGSADRNSPSPSSVASSDSGSTDEIQDEFEREADVEPMVS", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9Q7X1-1", "uniprot_id": "A0A8M9Q7X1_DANRE", "id": "A0A8M9Q7X1-1", "name": "", "aln": "-MSSLLFGEGFL------------------GGAVSGAPSDAVPRALRNDLGSNIHVLKTLNLRFRCFLAKVHELERRNKLLESQLKQATGQP--RYPGFSFTREVAVQT--DSLES---------------------------------------RLPGTIWSFTHILRHG-ERVKTVQGPGVTWTHPDGVGVQIDTITPELRALYNVLAKVKRERDEYKRKWEEELSRREQMEVMVQSLQENVNQSEAIQDELNEKVERLKAELVVFKSLMSDAGGRRRNKAVENQRKILDLKQMSDLDTKIQEKAMKVDMDICRRIDITAKLCDVAQQRNSEDMSKIFSPSRAPADRAVACRKKERKAVSDEESSEMDADPSSTSEEDA-PFNITDEMKRMLNQLHCSDNSFVARRETFEIDDDCDSLTWEENDDTLLLWEDFTNYNVPCSALTNGNGDCSTDGHEADSSLGSLIDETESLFKTREQEYQKTIGQIEMELATAKSDMNRHLHEYMEMCSMKRGLDVQMETCRRMIKG--GRNSPSISSSASSDSGNTDEIQEESDKDGETDGPIS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :.****** * **. :*. ...*. ***:*******:** **:****************:***.**:* .: * :*:** **** : *.. ********:*:: * * *:*******:*.***************:*******************:*****:: :::.**::*** .::::***:*:***:***********.****. *:**************************************:****. *. :**:**..**:: ** *.: . *:::. .:*********:*** ****::************:*********** *.. : :* * :..**.**.****:****::***:******:***********************************:*** .***** ** ******.*****:: :::.:.: :*", "identical_positions": 316, "similar_positions": 98, "identity": "55.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121031-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A6NH21-1", "uniprot_id": "SERC4_HUMAN", "id": "A6NH21-1", "name": "Serine incorporator 4", "aln": "MVGAKAGPSPGTSLGLAQQHSGGSSVLVKSPFCQVCCCGPAPCASCCHSRWPSLTASTCSRLFYILLHVGASAICCLLLSRTVVERVWGKTHRIQMPSGLCAHLFGLSDCPVLSGSGAVYRVCAGTATFHLLQAVLLVHLHSPTSPRAQLHNSFWLLKLLFLLGLCAIAFCIPDEHLFPAWHYIGICGGFAFILLQLVLITAFAHSWNKNWQTGAAQDCSWFLAVLLATLGFYSMAGVGAVLLFHYYTHPAGCLLNKMLLSLHLCFCGLISFLSIAPCIRLKQPRSGLLQASVISCYIMYLTFSALSSRPPERVILQGQNHTLCLPGLSKMEPQTPDISLAMLSASIMYACVLFACNEASYLAEVFGPLWIVKVYSYEFQKPSLCFCCPETVEADKGQRGGAARPADQETPPAPPVQVQHLSYNYSAFHFVFFLASLYVMVTLTNWFSYEGAELEKTFIKGSWATFWVKVASCWACVLLYLGLLLAPLCWPPTQKPQPLILRRRRHRIISPDNKYPPV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q5XK03-1", "uniprot_id": "SERC4_MOUSE", "id": "Q5XK03-1", "name": "Serine incorporator 4", "aln": "MMGAKVVTGRSTTQGLAQQH-GGVSNVVETPFNQASCCGPVSWTSGCHS----LTESRCSRLLYILLHVGASAICCLLLSKTVVERVWGKAHGIQMPSVLCAHLFGSSDCPVLSGSGAVYRVCAGTATFHLLQAVLLVRLHSPTNPRAQLHNSFWSLKLLFLLGLCVVAFCIPDEDLFPAWHYIGICGGFTFILLQLVLITAFAQSWNKNWQTGAAQDCSWLLGVSLATLGFYSMAGVGAVLLFHQYTHPDGCLLNKMLLSLHLCFCGLLSLLSIAPCIRRKQPNSGLLQASIISCYIMYLTFSALSSRPPETITFQGQNHTLCLPGRNKMEPQIPDTSVAVFSAGIMYACVLFACNEASYLAELFGPLWIIKVYKYEFQKPSVCFCCPQTVEPEDGQRS-RARSADQETPPAAQVQSQHLSYSYSGFHFAFFLASLYVMVTLTNWFSYEEAELEKTFTKGSWATFWVKVASCWACVLLYLGLLLAPLLAPHSESPPP--------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F5D2-1", "uniprot_id": "E7F5D2_DANRE", "id": "E7F5D2-1", "name": "", "aln": "MSTAQALHHSGVYN----------YFLNMVAYQICCCCGPAPCSLCCSFCPP-VKSSTSTRIMYTLFHILACTVSCLMLSKTVSEAVR---ENVPFFNVVCDEAHGGGDCQMLVGYSAVYRVCFGTACFYLMMAIFLIDVKSSQDFRALIHNGFWFLKFITMLGMIAAAFFIPTESFLHAWHYVGVVGGFSFILIQLILITAFAHTWNKNWLTGAAENKRWYVAVMCATLFFYTIATMAFTFMYKYYTHPAGCHLNKALLWTNLALCTIMSFIAITPCVQQKKPRSGILQASIICCYVMYLTFSALSSRPPEKVEYQGVNITICYPKVSRDEIQNEGNAVAIMGAAIMYCCVLFACNEASYLAEVFGPFWMIKVYRYEFQKASCCFCCPEAEDEEE-----FVIDENKGCQKVVHNETQRVAYSYFFFHFVFFLASLYVMMTLTNWFSYETAVLETTFTHGSYSTFWVKLSSCWACVVLYLWLLLGPLCQCQSDPKRPRRARIKR-RIAAHRHVSVSV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "* *:. .. : .: .****.. : * :. * .:*::* *:*: *.::.**:**:** * * . : : . :* . .* .** :* * .****** *** *:*: *::*: ::*. . ** :**.** **:: :**: . ** ** * :: ****:*: ***:***:**:******::***** ****:: * :.* *** **::* :. .:::: **** ** *** ** :*.:* ::*:::*:**:: *:*.**:****:*.**:************** : ** * *:* * .: * * . ::*::.*.***.**************:***:*::*** *****.* *****:: : :. . :: . : *:::*.* ***.*********:********* * **.** :**::*****::******:*** ***.** :: * ", "identical_positions": 230, "similar_positions": 133, "identity": "44.4%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121031-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q12873-1", "uniprot_id": "CHD3_HUMAN", "id": "Q12873-1", "name": "ATP-dependent chromatin remodeler CHD3", "aln": "----------------------------------MKAADT--------VILWARSKNDQLR----------ISFPPGLCWGDRMPDKDDIRLLPSALGVKKRKRGPKKQKENKPGKPRKRKKRDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKKGEGDGGQKQ----VEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPMSKMMTILGAKWREFSANNPFKGS--AAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPP-ALPPPPAADIQPPPIRRAKTKEGKGPGHKRRSKSPRVPDGRKKLRGKKMAPLKIKLGLLGGKRKKGGSYVFQ------SDEGPEPEAEESDLDSGSVHSASGRPDGPVRTKKLKRGRPGRKKKKVLGCPAVAGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEKEGVQWEAKEEE-EEYEEEGEEE-------GEKEEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQ-ADGNPDVPPPRPLQGRSEREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSG--EDDGKSDKRKVKDP------HYAEMEEKYYRFGIKPEWMTVHRIINHSVDKKGNYHYLVKWRDLPYDQSTWEEDEMNIPEYEEHKQSYWRHRELIMGEDPA----QPRKYKKKKKELQGDGP---------PSSPTNDPTVKYETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYKEGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKGGKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGPHMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIMMDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLMLLQKMLRKLKEQGHRVLIFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKMMLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENE-------------------------------------GENKE-EDSSVIHYDNEAIARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQE-ENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRVRKQVNYND-------AAQEDQ-------DNQSEYSVGSEEE--DEDFDERPEG---RRQSKRQLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWLVRDLRGKTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKKKVQEFEHINGRWSMPELMPDPSA------DSKRSSRASSP-TKTSPTTPEASATNSPCTSKPATPAPS-EKGEGIRTPLEKEEAENQEE---KPEKNSRIGEKMETEADAPSPAPSLGERLEPRKIPLEDEVPGVPGEMEPEPGYRGDREKSATESTPGERGEEKPLDGQEHRER-------PEGETGDLGKREDVKGDRELRPGP-RDEPRSNGRREEKTEK------------------------------------------PRFMFNIADGGFTELHTLWQNEERAAISSGKLNEIWHRRHDYWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKLLEQALVIEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANAVLHKVLNQLEELLSDMKADVTRLPATLSRIPPIAARLQMSERSILSRLAS-KGTEPHPTPAYPPGPYATPPGYGAAFSAAPVGALAAAGANYSQMPAGSFITAATNGPPVLVKKEKEMVG-ALVSD--GLDRKEPRAGEVICIDD----------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "B1AR17-1", "uniprot_id": "B1AR17_MOUSE", "id": "B1AR17-1", "name": "", "aln": "MASPLRDEEEEEEEMVVSEEEEEEEEEGDEEEEEVEAADEDDEEEDEEGVLGRGPGHDRSRDRHSPPSCHLFPPPPPPLPPPPPPDKDDIRLLPSALGVKKRKRGPKKQKENKPGKPRKRKKLDSEEEFGSERDEYREKSESGGSEYGTGPGRKRRRKHREKKEKKTKRRKRGEGDGGHKQ----VEQKSSATLLLTWGLEDVEHVFSEEDYHTLTNYKAFSQFMRPLIAKKNPKIPMSKMMTILGAKWREFSANNPFKGS--AAAVAAAAAAAAAAVAEQVSAAVSSATPIAPSGPPPALPPPPAPEIQPPPIRRAKTKEGKGPGHKRRNKSPRVPDGRKKLRGKKMAPLKIKLGLLGGKRKKAGSCAFQ------SEEGHEPEAEESDLDSGSVHSASGWPDGPVRAKKLKRGRPGRKKKKVLGCPAVTGEEEVDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELDRAPEGKWSCPHCEKEGVQWEAKEEE-EEYEEEGEE--------GEKEEEDDHMEYCRVCKDGGELLCCDACISSYHIHCLNPPLPDIPNGEWLCPRCTCPVLKGRVQKILHWRWGEPPVAVPAPQQ-ADGNPDVPPPRPLQGRSEREFFVKWVGLSYWHCSWAKELQLEIFHLVMYRNYQRKNDMDEPPPLDYGSG--EDDGKSDKRKVKDP------HYAEMEEKYYRFGIKPEWMTVHRIINHSMDKKGNYHYLVKWKDLPYDQSTWEEDEMNIPEYDDHKQSYWRHRELIMGEDPA----QPRKYKKKKKELQGDGP---------PSSPTNDPTVKYETQPRFITATGGTLHMYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLYKEGHTKGPFLVSAPLSTIINWEREFQMWAPKFYVVTYTGDKDSRAIIRENEFSFEDNAIKGGKKAFKMKREAQVKFHVLLTSYELITIDQAALGSIRWACLVVDEAHRLKNNQSKFFRVLNGYKIDHKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGPHMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKYILTRNFEALNSRGGGNQVSLLNIMMDLKKCCNHPYLFPVAAMESPKLPSGAYEGGALIKSSGKLLLLQKMLRKLKEQGHRVLIFSQMTKMLDLLEDFLDYEGYKYERIDGGITGALRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKMMLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDENE-------------------------------------GENKE-EDSSVIHYDNEAIARLLDRNQDATEDTDVQNMNEYLSSFKVAQYVVREEDKIEEIEREIIKQE-ENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRVRKQVNYND-------AAQEDQ-------DNQSEYSVGSEEE--DEDFDERPEG---RRQSKRQLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAVMRWGMPPQDAFTTQWLVRDLRGKTEKEFKAYVSLFMRHLCEPGADGSETFADGVPREGLSRQQVLTRIGVMSLVKKKVQEFEHINGRWSMPELMPDPSA------ESKRSSRASSP-TKTSPTTPEASTTNSPCTSKPATPAPS-EKGDGVRTPLDKDDTENQEE---KPEKNSKVGEKMEAEVDSPSPAPSLGERLEHRKILLEDEAPGVPGETEPEPGYRGDREKSASEPTPGERGEEKPLDVQEHRER-------TEGETGDLGKREDVKADRELRLGPPRDEPRPNGRREEKVEK------------------------------------------PRFMFNIADGGFTELHTLWQNEERAAISSGKLNEIWHRRHDYWLLAGIVLHGYARWQDIQNDAQFAIINEPFKTEANKGNFLEMKNKFLARRFKLLEQALVIEEQLRRAAYLNLSQEPAHPAMALHARFAEAECLAESHQHLSKESLAGNKPANAVLHKVLNQLEELLSDMKADVTRLPATLSRIPPIAARLQMSERSILSRLAS-KGTEPHPTPAFPPGPYATPPGYGAAFSAAPVGALAAAGANYSQMPAGSFITATTNGPPVLVKKEKEMVG-ALVSDGLGLDRKEPRAGEVICIDD----------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M3B137-1", "uniprot_id": "A0A8M3B137_DANRE", "id": "A0A8M3B137-1", "name": "", "aln": "MSSLLRSCEEDEGTAVNSEGGDFDEEEEDDGDLDENASDIN---------SPAAPRETAAR-----------AAPDDGDDIGEASDRDNLGKKKRGPKKKKETKKKDKEKEGKIAKARKRKKIESDIERDSEPD-YAMNSDSAASDYGGE--KKKKKKHKDKKEKKTKKKKKEDEDSTHEETTKPVEMKTSAQLAREWGLEDVDHTFTEEDYRTLTNYKAFSQFLRPMIAKKNPKIPMSKMMTILGAKWREFSSNNPFKGS--AAAVAAAAAAAAAAVAEQVSAATASPE-----------PPP-----QPPPLRKAKTKEGKGPGYKKRSKSPRVSD-KKKPKPKKMAPLRIKLGAIGNKRKK-------------SSSSEEVDEDDSEQENSSVHSSSVRSDSSGRVKKNKRGRPAKKKKKAL------GDEDGDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLEPELEKAPEGKWSCPHCEKEGIQWEAKEEDFEEFEEECDDVRDVESGLGGEEEEDDHMEFCRVCKDGGELLCCDSCPSSYHIHCLNPPLPEIPNGEWLCPRCTCPPIKGRVQKILHWRWGEPPPPVPVPPP-PDAPPDAPPPPPMKGRPEREFFVKLTAQSYWHCTWITELQLEIFHSVMFRNYQRKTDMDEPPSLDYGSGGEEDSGKSEKRRAKDP------QYAILEEKYYRYGIKPEWMMVHRIINHSVDKKGNYHYLVKWRDLTYDQCTWERDELDIPEFALHKTAYWRHREAVMKEDPE----KPRKMRRRE---ENDEA---------PSTPVNDPTIKYEEQPEFVTETGGTLHLYQLEGLNWLRFSWAQGTDTILADEMGLGKTIQTIVFLYSLFKEGHTKGPFLVSAPLSTIINWEREFEMWAPDFYVVTYTGDKDSRAIIRENEFTFDDTAVKGGKKAFKLRREAPIKFHVLLTSYELVTIDQNVLKSIDWACLVVDEAHRLKNNQSKFFRRLNDYKIDHKLLLTGTPLQNNLEELFHLLNFLTPNRFNNLEGFLEEFADISKEDQIKKLHDLLGPHMLRRLKADVFKNMPAKTELIVRVELSPMQKKYYKFILTRNFEALNSKGGGNQVSLLNIMMDLKKCCNHPYLFPVAAAEAPKTPSGAYEGVGLTKASGKLMLLQKMLRKLKEQGHRVLVFSQMTKMLDLLEDFLDSEGYKYERIDGGITGALRQEAIDRFNAPGAVQFCFLLSTRAGGLGINLATADTVIIFDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRASVEERITQVAKRKMMLTHLVVRPGLGSKAGSMSKQELDDILKFGTEELFKDEIEA------------------------------------GDNKD-DDMSVIHYDNAAIERLLDRSQDATDDSDMQNMNEYLSSFKVAQYTVKEDDKIEEIEREIIKQE-ENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRVRKQVNYND-------AAQEDQEWHADISDNQSEYSVGSEEE--DEDFDERPEG---RRQSRRQLRNEKDKPLPPLLARVGGNIEVLGFNTRQRKAFLNAIMRWGMPAQDAFSSQWLVRDLRGKSEKEFKAYVSLFMRHLCEPVADGSETFADGVPREGLCRQPVLTRIGVMSLVKKKVQEFEHINGKWSMPELKPEITV------DSKKSSRASSPTIKTDTPTPELSCNNTPCTSKPATPSPP-DKTEKSAKEAEKDEAESLTEPEREREKEKAKEAKEGESVESTEHGEATGNEGEKDPITSEKSQTSESPAAAASDDSKTKENPDISQSPPKEKNEKEKQEEEEGKEKEPSTEKPSDSPSVKEESKEALKGDKKEKAGEEKEKTEASSPPSETTEKKDKLDQSSEVKKEEVKGERDAGKEVRVQREEVPKVISRPAERPRFMFNIADGGFTELHTLWQNEERAAISSGKINEIWHRRHDFWLLSGIVCHGYARWQDIQNDPQFAIINEPFKTQANKGNFLEMKNKFLARRFKLLEQALVIEEQLRRAAYLNMTQDPTHPAMALNARFAEVECLAESHQHLSKESLAGNKPANAVLHKVLNQLEELLSDMKADVTRLPATLSRVPPITARLQMSERSILSRLAN-KGNETHTPPPIPPGPYATPQNFGPPFTPAPSAALALAGANYSQMPPGSFISEAPS---CLKTKEHDVLQRQRVVDLWKDGKSEGTIGQELRMPKSTVHSIIVKYRLSNTVENLPRNGRPKKP", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "D3ZD32-1", "uniprot_id": "CHD5_RAT", "id": "D3ZD32-1", "name": "ATP-dependent chromatin remodeler CHD5", "aln": "MRGPLGTEEELPR---------------------LFAEEMENEEE---------------------------------MSEEEDGGLEGFEDFFPAEPVSLPKKKPKKLKESK-SKGKRKKKEGSNDELSENEEDLEEKSESEGSDYSPT--KKKKKKLKEKKEKKAKRKKRDEDEEDNEDG-GLKEPKSSGQLMAEWGLDDVDYLFSEDDYHTLTNYKAFSQFLRPLIAKKNPKIPMSKMMTVLGAKWREFSANNPFKGS--SAAAAAAAVAAAVETVTIAPPLAISPQ-----------QVP-----QPLPVRKAKTKEGKGPGVRKKNKG--AKDSKKKGRGKRVAGLKFRFGGIS-KRKK-------------GSSSEEDEPEDSDLDNASIHSSSVRSECSAALGKKNKRR--RKKKR---------IDDGDGYETDHQDYCEVCQQGGEIILCDTCPRAYHLVCLDPELEKAPEGKWSCPHCEKEGIQWEPKDDD--EEEEEG----------GCEEEEDDHMEFCRVCKDGGELLCCDACPSSYHLHCLNPPLPEIPNGEWLCPRCTCPPLKGKVQRILHWRWTEPPAPFMVGLPGPEVEPGMPPPRPLEGIPEREFFVKWAGLSYWHCSWVKELQLELYHTVMYRNYQRKNDMDEPPPFDYGSG--DEDGKSEKRKNKDP------LYAKMEERFYRYGIKPEWMMVHRILNHSFDKKGDVHYLIKWKDLPYDQCTWEIDEIDIPYYDNLKQTYWGHRELMLGEDAR----LPKRLVKKGKKLKDDKQE------KPPDTPIVDPTVKFDKQPWYIDSTGGTLHPYQLEGLNWLRFSWAQGTDTILADEMGLGKTVQTIVFLYSLYKEGHSKGPYLVSAPLSTIINWEREFEMWAPDFYVVTYTGDKESRSVIRENEFSFEDNAIRGGKKVFRMKKEVQIKFHVLLTSYELITIDQAILGSIEWACLVVDEAHRLKNNQSKFFRVLNSYKIDYKLLLTGTPLQNNLEELFHLLNFLTPERFNNLEGFLEEFADISKEDQIKKLHDLLGPHMLRRLKADVFKNMPAKTELIVRVELSQMQKKYYKFILTRNFEALNSKGGGNQVSLLNIMMDLKKCCNHPYLFPVAAVEAPMLPNGSYDGSSLVKSSGKLMLLQKMLKKLRDEGHRVLIFSQMTKMLDLLEDFLEYEGYKYERIDGGITGGLRQEAIDRFNAPGAQQFCFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQNKKVMIYRFVTRASVEERITQVAKRKMMLTHLVVRPGLGSKSGSMTKQELDDILKFGTEELFKDDVEGMMSQGQRPTTPIPDVQSTKGGSLAAGAKKKHGGTPPGDNKDVEDSSVIHYDDAAISKLLDRNQDATDDTELQNMNEYLSSFKVAQYVVREEDGVEEVEREVIKQE-ENVDPDYWEKLLRHHYEQQQEDLARNLGKGKRIRKQVNYND-------ASQEDQEWQDELSDNQSEYSIGSEDE--DEDFEERPEGQSGRRQSRRQLKSDRDKPLPPLLARVGGNIEVLGFNARQRKAFLNAIMRWGMPPQDAFNSHWLVRDLRGKSEKEFRAYVSLFMRHLCEPGADGAETFADGVPREGLSRQHVLTRIGVMSLVRKKVQEFEHVNGKYSTPDLVPEGPE------GKKPGEVISSD--------PNTPVPASPAQLPPAPLGLP-DKMEAQLGYTDEKESGTQKP-------------KKSLEIQALPTALDRVEAEDKHQSSDSKDRAREERMEEVEKAQGSPEQPLKEETLPDKEPVPDKLELSLSHSN----------DFRPDDPKAEEKEPTETQQNGDREEDE-EGKKEDKNGK------------------------------------------FKFMFNIADGGFTELHTLWQNEERAAVSSGKIYEIWHRRHDYWLLAGIVTHGYARWQDIQNDPRYMILNEPFKSEVHKGNYLEMKNKFLARRFKLLEQALVIEEQLRRAAYLNMTQDPNHPAMALNARLAEVECLAESHQHLSKESLAGNKPANAVLHKVLNQLEELLSDMKADVTRLPSMLSRIPPVAARLQMSERSILSRLTN-RAG----DPTIQQGAFGSSQMYNNSFGPNFRGPGPGGIVNYNQMPLGPYVTGR---------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O97159-1", "uniprot_id": "CHDM_DROME", "id": "O97159-1", "name": "ATP-dependent chromatin remodeler Mi-2", "aln": "MASEEENDDNFQE-------------EEEAQEDNAPAAELSN---------------------------------DSDAPLKPNNDEDDDYDPEDSRRKKKGKKRKTRKGEEKGRKKKKRKKNESEEDSDFVQHDEEVEYPSTS-----------KRGRKRKEEKQAAKEKESASSG----------MPSVEDVCSAFSVCNVEIEYSEEELQSLTTYKAFMHHVRPILQKENPKIAAPKLVMLVAAKWREFCESNPHIQQEGGAAGSGGSAGQARSVTGDEPEEPRSSRSSRNEKPDDIYEEAVEEEEEEEEEEKKPRRKRSGRGKKGRRPSGKVPTLKIKLLGKRKRDSSDEEQDASGASERDSDLEFERMLQKSDDSADEKEAPVSSKADNSAPAAQDDGSGAPVVRKKAKTKIGNKFKKKNKLKKTKNFPEGEDGEHEHQDYCEVCQQGGEIILCDTCPRAYHLVCLEPELDEPPEGKWSCPHCEADGGAAE-------------------------EEDDDEHQEFCRVCKDGGELLCCDSCPSAYHTFCLNPPLDTIPDGDWRCPRCSCPPLTGKAEKIITWRWAQRS---------NDDGPSTSKGSKNSNSRVREYFIKWHNMSYWHCEWVPEVQLDVHHPLMIRSFQRKYDMEEPPKFEESLDEADTRYKRIQRHKDKVGMKANDDAEVLEERFYKNGVKPEWLIVQRVINHRTARDGSTMYLVKWRELPYDKSTWEEEGDDIQGLRQAIDYYQDLRAVCTSETTQSRSKKSKKGRKSKLKVEDDEDRPVKHYTPPPEKPTTDLKKKYEDQPAFLEGTGMQLHPYQIEGINWLRYSWGQGIDTILADEMGLGKTIQTVTFLYSLYKEGHCRGPFLVAVPLSTLVNWEREFELWAPDFYCITYIGDKDSRAVIRENELSFEEGAIRGSK--VSRLRTTQYKFNVLLTSYELISMDAACLGSIDWAVLVVDEAHRLKSNQSKFFRILNSYTIAYKLLLTGTPLQNNLEELFHLLNFLSRDKFNDLQAFQGEFADVSKEEQVKRLHEMLGPHMLRRLKTDVLKNMPSKSEFIVRVELSAMQKKFYKFILTKNYEALNSKSGGGSCSLINIMMDLKKCCNHPYLFPSAAEEATTAAGGLYEINSLTKAAGKLVLLSKMLKQLKAQNHRVLIFSQMTKMLDILEDFLEGEQYKYERIDGGITGTLRQEAIDRFNAPGAQQFVFLLSTRAGGLGINLATADTVIIYDSDWNPHNDIQAFSRAHRIGQANKVMIYRFVTRNSVEERVTQVAKRKMMLTHLVVRPGMGGKGANFTKQELDDILRFGTEDLFK-----------------------------------------EDDKE----EAIHYDDKAVAELLDRTNRGIEE-KESWANEYLSSFKVASYATKEEE--EEEETEIIKQDAENSDPAYWVKLLRHHYEQHQEDVGRSLGKGKRVRKQVNYTDGGVVAADTTRDDSNWQDNGSEYNSEYSAGSDEDGGDDDFDDQNGA---ERKAKRRLERRDDRPLPPLLARVGGNIEVLGFNARQRKSFLNAIMRYGMPPQDAFNSQWLVRDLRGKSERNFKAYVSLFMRHLCEPGADNAETFADGVPREGLSRQHVLTRIGVMSLIRKKVQEFEHINGYYSMPELILKPCEPVRSALKQDVAALEAPPTGGNVDKSATTSNSVTPATSAAPSPAPASEKGEDKDKDSEKEKDKTSAEKSEVKQEQEAEEDKKPGDVKQENPVEEAAGDTKPSDAEVKTEVAKTEPKEE-TKDPEVKEEPKTEEKEKEKVDDKKPIPPTTVIDDDDDDVMIVKEDGELEKPSASSPKDQKAVAAATSAATGATGKGAEDSLEVLK---------------------------------------RKFMFNIADGGFTELHTLWLNEEKAAVP-GREYEIWHRRHDYWLLAGIVTHGYGRWQDIQNDIRFAIINEPFKMDVGKGNFLEIKNKFLARRFKLLEQALVIEEQLRRAAYLNLAQDPSHPAMSLNARFAEVECLAESHQHLSKESLAGNKPANAVLHKVLNQLEELLSDMKSDVSRLPATLARIPPVAQRLQMSERSILSRLAATAGNASNAAQLMAQFPAGFQGTTLPAFTSGPAGNFANFRPQFSVPGQLSNNSGV---------------------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * : . :. . . .: : * * * :::** *: : . . : * . :: : *:**:: :.*. . : : :.: :*: ::*:: ::**.**** :.:**:: *:****. .*:: ::.******. .**. . .** :..:.. * .. . *. . : .: :: .* * : : . . : * *: . . :: .... * : *. . * ::. . . * : : .* *: : :. * :*****************************:***:..*********** :* * :*::*:* *:**************:* *:** .****** **:*:* ****:** :.*:.::*: *** : . : *. . .. **:*:* ***** * *:**::.* :* *.:*** **:*** :: . . : * :*: .. :**::*: *:****: *:*::** :.*. **:**::*.**:.*** : :* * * * . .:: : :.* *..* * . *:: ** :: ** ** **:**:****:**.** *************:**:.*****:**** :**:**:.****::******::***.** :** ***:**::*****::*:: *::*.* . : . **:********:::* * ** ** **********.******* **.*.* :***********************: ::**:*:.* ****:***:*:*:**::**********:**:****:*:*:******* ****:**:***:*:*****:.**.. **:***************** ** *:. ..* *: .* *::***:**.***::*: :.****:*********:*****: * ************ ************** ** **********************:********************* :********** *****:******************:*.*...::********:****:*** ::*: ..****: *: .****.: . :: . . **********.*..:*:: ** * *:***: ** ** ** *********:***:.*.******:******.* ::::*. : :**** **::: *:**::: . .*:::*:*. *:*******************:****:****:**:***.****.::*********:*::*:************* **.:************.** **********::********:** :* *:* . .. . :. . . :*. ... . . :* : ::.. . * . . . . . . .: : : . . : . : : :***************** ***:**:. *: ********:***:*** ***.******** :: *:***** :. ***:**:*****************************::*:* ****:*:**:**.****************************************:**:***: *:*:**:: *************: . . . .* . . . ::. . : ", "identical_positions": 906, "similar_positions": 436, "identity": "40.34%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121031-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P32037-1", "uniprot_id": "GTR3_MOUSE", "id": "P32037-1", "name": "Solute carrier family 2, facilitated glucose transporter member 3", "aln": "-------------MG-------------TTKVTPSLVFAVTVATIGSFQFGYNTGVINAPETILKD----------FLNYTLEERLEDLPSEGLLTALWSLCVAIFSVGGMIGSFSVGLFVNRFGRRNSMLLVNLLAIIAGCLMGFAKIAESVEMLILGRLLIGIFCGLCTGFVPMYIGEVSPTALRGAFGTLNQLGIVVGILVAQIFGLDFILGSEELWPGLLGLTIIPAILQSAALPFCPESPRFLLIN-KKEEDQATEILQRLWGTSDVVQEIQEMK----------DESVRMSQEKQVTVLELFRSPNYVQPLLISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEP--IYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAVCSVFMTISLLLKD--------------------DYEAMS---FVCIVAILIYVAFFEIGPGPIPWFIVAELFSQGPRPAAIAVAGCCNWTSNFLVGMLFPSAAAYLGAYVFIIFAAFLIFFLIFTFFKVPETKGRTFEDIARAFEGQAHS--GKGPAG---VELNS------MQPVKETPGNA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q07647-1", "uniprot_id": "GTR3_RAT", "id": "Q07647-1", "name": "Solute carrier family 2, facilitated glucose transporter member 3", "aln": "-------------MG-------------TAKVTPSLVFAVTVATIGSFQFGYNTGVINAPETIIKD----------FLNYTLEERLEDLPREGLLTTLWSLCVAIFSVGGMIGSFSVGLFVNRFGRRNSMLLVNLIAILGGCLMGFAKIAESVEMLILGRLIIGIFCGLCTGFVPMYIGEVSPTALRGAFGTLNQLGIVVGILVAQVFGLDFILGSEELWPGLLGLTIIPAILQSAALPFCPESPRFLLIN-RKEEDQATEILQRLWGTPDVIQEIQEMK----------DESIRMSQEKQVTVLELFKSPSYFQPLLISVVLQLSQQFSGINAVFYYSTGIFQDAGVQEP--IYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAVCSVFMTISLLLKD--------------------EYEAMS---FVCIVAILVYVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGMFFPSAAAYLGAYVFIIFAAFLVFFLIFTSFKVPETKGRTFEDITRAFEGQAHS--GKGSAG---VELNS------MQPVKETPGNA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q8TDB8-1", "uniprot_id": "GTR14_HUMAN", "id": "Q8TDB8-1", "name": "Solute carrier family 2, facilitated glucose transporter member 14", "aln": "--MEFHNGGHVSGIGGFLVSLTSRMKPHTLAVTPALIFAITVATIGSFQFGYNTGVINAPETIIKE----------FINKTLTDKANAPPSEVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLIN-RKKEENATRILQRLWGTQDVSQDIQEMK----------DESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQP--IYATISAGVVNTIFTLLSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKN--------------------HYNGMS---FVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHG--ADRSGKDGVMGMNS------IEPAKETTTNV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P11169-1", "uniprot_id": "GTR3_HUMAN", "id": "P11169-1", "name": "Solute carrier family 2, facilitated glucose transporter member 3", "aln": "-------------MG-------------TQKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKE----------FINKTLTDKGNAPPSEVLLTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFILGSEELWPLLLGFTILPAILQSAALPFCPESPRFLLIN-RKEEENAKQILQRLWGTQDVSQDIQEMK----------DESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQEP--IYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKD--------------------NYNGMS---FVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGLLFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAFEGQAHG--ADRSGKDGVMEMNS------IEPAKETTTNV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58HJ95-1", "uniprot_id": "A0AC58HJ95_DANRE", "id": "A0AC58HJ95-1", "name": "Solute carrier family 2, facilitated glucose transporter member 5", "aln": "----MVSESAVHLLG-----------SKGKKVTLCLMFCVSTAVIGSLQFGYNIGVINAPDVKVQN----------FFRNVTLVRTGEPMDDYTVTTLWSVAVAIFNFGGMIGSLNVGALVNKLGGRKSMLLSNILALIGGGLMGLSSICSSYELLIVGRLVIGVFCGLSTGLTPMYVGEIAPTALRGAFGTLHQLGVVIGILVAQILGLESLLGSQTLWPLLLALTALPAVIQSIMLIFCLESPRYLLIS-LNKEDEARQALTSLRGHSDVEDDIREMK----------DEAMKMSMEKRVSIPELFRNPAYRQPIIIAIILQLSQQLSGINAVMYYSTEIFRNAGITEP--VFATIGMGVVNTVFTVVSLFLVERAGRRTLHLIGLTGMTFCVLLVTISLKLVDSEIEKAKLLQNGTAIIDSASPSEGISTVKVLAILAVFGFVASFEMGPGPIPWFIVAELFAQGPRPAAMAVAGCCNWTASFLVGLLFPILSKKIGAYVFIIFLILLVVFIVFTYFRVPETKGRTFEDIASGFSNAADSNTANYKSAEGAVSLP-------ISPSSEKFQMTELAGQEKS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q8IRI6-5", "uniprot_id": "GTR1_DROME", "id": "Q8IRI6-5", "name": "Glucose transporter type 1", "aln": "----------MAFLC-------------APGLTFFLTYSIFSAVLGMLQFGYNTGVINAPEKNIEN----------FMKDVYKDRYGEDISEEFIQQLYSVAVSIFAIGGMLGGFSGGWMANRFGRKGGLLLNNVLGIAGACLMGFTKVSHSYEMLFLGRFIIGVNCGLNTSLVPMYISEIAPLNLRGGLGTVNQLAVTVGLLLSQVLGIEQILGTNEGWPILLGLAICPAILQLILLPVCPESPRYLLIT-KQWEEEARKALRRLRASGSVEEDIEEMR----------AEERAQQSESHISTMELICSPTLRPPLIIGIVMQLSQQFSGINAVFYYSTSLFMSSGLTEESAKFATIGIGAIMVVMTLVSIPLMDRTGRRTLHLYGLGGMFIFSIFITISFLIKE--------------------MIDWMS---YLSVVATLGFVVFFAVGPGSIPWMITAELFSQGPRPSAMAIAVLVNWMANFVVGIGFPSMKTALENYTFLPFSVFLAIFWIFTYKKVPETKNKTFEEILALFRHNNGRSMLNCTNSLEPQSMNSGIEHAALMVSEEKTQHDSLFGTTSFSLTVEGMGPYPLSDSTNLLGPGSSSYGPGGVLGLAGSGSGLGGQCYTNYGTNLQTPQAARKCHYDEVDDYSFRRHSAHGRITQMKGKPLILGPTIKKDKKKERTDWLTASERFLEGGRSTHQGRSAASAPHHPRQPPPVCPSSGPXLRSASPPDSASVRSTSRAEEPHQPQQVHHQQQQVHHQQQHQSRYATHEYVHCSYEKEVVCDQANPSQAPPQQPAPPVQQHQQQPPPPLHHCQQRKHSHSPHHSRHTSPHSHHHHSHHSRHSRRSRRQGSGSLPGAHQGSANHSVMRPSICTSRRHRSVTDISTTNVCQDPACSDREVQEIMVRRTCCNTTATNSSSRTELAQCFAEDLYGSSRRPSSCCTSSDYCYQTDSTSLYGSRSSLSRNNSIKSASALVRKHHRSQRSLLPEHRHPSYTSISLRGLNASRPNSQLGSLTSIFDRAKNMAPEGSTLERQSSKGALGSSELPEYACSPSPIRWSFLADGRSPSEMEGAVGGGPEREQEEEDKLDAWQVPEPEPEKKPCRKITTSSSVYDEGPSTSAAAARKRRGSKGSRGSKGSGSYHCEFEDEATTTVMFHQDAGEAYNNCCSNNYNYIQCNTYLDQDLQITSEDIHQYLSKGDATASDILNNSKNYPFQPSNALEFQYKNNFQQGQANANNNNTNTTNTASSDAAECFQNYRAISKETNLNQTSTEQLSPTNINLSTSSNNINIVFSSSLERNANEVKFINNRSGASGGSEMGCEVGHHAGYLPYTYPSYDYTNMSGNSHFEKPLGIDELPKEFCGLEGAGGGGASTTSEHSSSLPSPQPLTHHQQLHHFESFDAASEHNLLAAQPMSPGSPLSGSVNPAGDDFVQMHHYHHANSPHSQSHHSHAHTHTHGHHVHHLLNHPAYDLTDDQFRLGSALKRVRKRARKYTDFLRKK", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P53142-1", "uniprot_id": "VPS73_YEAST", "id": "P53142-1", "name": "Vacuolar protein sorting-associated protein 73", "aln": "MNRILSSASLLSNVSMP--------RQNKHKITKALCYAIIVASIGSIQFGYHLSELNAPQQVLSCSEFDIPMEGYPYDRTWLGKRGYKQCIPLNDEQIGIVTSVFCIGGILGSYFATSLANIYGRKFSSLINCTLNIVGSLIIFNS---NSYRGLIIGRILVGISCGSLIVIIPLFIKEVAPSGWEGLLGSMTQICIRLGVLLTQGIALPLTDSYR--WRWILFGSFLIAVLNFFMWFIVDESPKWLLAHGRVTDAKLSLCKLRGVTFDEAAQEIQDWQLQIESGDPLIEPTTTNSISGSNSLWKYLRDRTNVKSRHVITVLLFGQQFCGINSIVLYGTKIISQLYPQHA--IRINFFISMVNVLVTILVSLLIHSLPRKPLLMTSTVLVSVTAFIMGIAMNHNKM----------------------------NLLIVFSFIYMGVFTMGLNPLPFIIMREVSKPQDMVLAQRYGTICNWVGTFIIAYTFPIIHDVLSGYVFIIFAIIACSISAFIWKKVPETK--------RSG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" }, { "uniprot_ac": "P38142-1", "uniprot_id": "YB91_YEAST", "id": "P38142-1", "name": "Probable metabolite transport protein YBR241C", "aln": "---MAETERLMPNGGS---------RETKPLITGHLILGTIVACLGSIQYGYHIAELNAPQEFLSCSRFEAPDENISYDDTWVGQHGLKQCIALTDSQYGAITSIFSIGGLFGSYYAGNWANRYGRKYVSMGASAMCMVSSLLLFFS---NSYLQLLFGRFLVGMSCGTAIVITPLFINEIAPVEWRGAMGSMNQVSINLGILLTQTLALKYADSYN--WRWLLFSGSVIAVANILAWLKVDESPRWLVSHGFVSEAETALFKLRPGTYQQAKQEIQDWQRSHGHNR---DPESSEETHSGPTLWQYVTDPSYKKPRTVILAILSCQQFCGINSIIFYGVKVIGKILPDYS--IQVNFAISILNVVVTLAASAIIDHVGRRPLLLASTTVMTAMSLLISVGLTLSVS----------------------------FLLVTATFVYIAAFAIGLGPIPFLIIGELSYPQDAATAQSFGTVCNWLATFIVGYLFPIGHGLMGGYVFAIFAAIAAMFATYVYKRVPETKGKTTYSEVWAGY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* * * :* :*:**: . :***: :. . : . .::* .**::*. .* * : : : .. :: * *:.**:::*: ** : *::: *::* .* :*:: *: : :*:*::* :.: . . * :* *: : ***::*: : : .. ::*.: : . : : . . : : **:.***::. *.. :: . .: . : .:.*: ::. *:.* : . : :: :.: : : : :: * :* ..:*::* *: * . ** ..*::. ** : *.* * : : : :****: ", "identical_positions": 67, "similar_positions": 133, "identity": "4.45%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121101-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "D3ZH28-1", "uniprot_id": "D3ZH28_RAT", "id": "D3ZH28-1", "name": "Alpha-protein kinase 3", "aln": "MGSRRALGRGWGLGGRAGTGGDGEDDGPVWTPGPASRSYLLSVRPEASLSSNRLSHPSSGRSTFCSIIAQLTEETQPLFETTLKSRAVSEDSDVRFTCIVTGYPEPEVTWYKDDIELDRYCGLPKYEITHQGNRHTLQLYRCREEDAAIYQASARNTKGIVSCSGVLEVGTMTEYKIHQRWFAKLKRKAAAKMREIEQSWKHGKEASGEADT-LRKISPDRFQR------------------------KRRLSGAEEAVLPAPLRGTEEGPSAAWQEGE------AESTQHPGLGMINSFAPGEAPTNGEPAPENGEDGEHGLLTYICEVMELGPQNTPPKESGAKKKRKDEESKPGGQKPELGKAEGSQ-------CSSENGIPSSDKLNSSRREKKSRDVQPTQNQTRDRVARGPGPSGIESTRKTASVLGTQDKVQDVPALAPAPAP----APAPVPVPAPAPVPSLSSEQVYFSLKDMFMESTRAGRSQEEEKSPPPSTRVAGESPSGKVPVKARGEKVPMVSGQPTSSTVPPPIKP-------LNRKRFAPPKSKVESTTSS----SSSQTPESVAQSLGKAPPPASAQVPTPPARR--------------------RHGTRESPLQGQTSHKTPG---------------------EALESPATMAPATSASSSSDTISVGHSTS--------------GNQGVTEPMDTETQEEGRTLANGRTSGRQKTQTDGKLQVDGRTQGD----EAQTLQR-----------------------------------TQTNEKAPMNVVTQGSERPESDRSSQKDLVTQRRVDTQVGQTQAGERWQQD--------------PRDARIQEE------KETQSVG-SIPTALETQPEQP-----------SVVSLSSVPGALKLSPSECPTEPQATECSERSTEASYIQEKSGLMLGSEEADFRS---HENTLLGPPSGNHTYSTQLPTEGNSEHLVGETHQRPEWLG--EAKQEDSLLQSPKKEQLQETLYVDLAIGHSADLSQEVPSLPSLPG------TDLTNSLQEGLPSTTASQHTNADVPLPSPDQDLPSSAPTLQLGPGSPTQSHPPEVMATSSEGACAKEPDVDGRSSGTRSCDPGLIDSLKNYLLLLLKLSSP--------------------------------EAGEARAESQEVPATGGLTSSSALVPTVEVAGLSPRTSRRILDR---------------VENNHLVQSAQTLLLSPCTSRRLTGLLDREVQAGQQALAAAQCSRGPCPSPSPLTIPAIVVGEE-------GSATGEGEDSRER-----TSQESDKAGLLGEV-------DGQTVES-RTQEPCQEEAIPG----------------------EALTGLPAATPEELALGARRKRFLPKVRAGSDGEVNKAEERESPTVSPRGPRKGLAPGSPG----TPGRERRSPTQARKASMLEVPGTEEEP-------------------------ASGDLVTRPKASGLESEP--------------AVDEGKQEALAKPRKAKDLLKAPQVIRKIRVEQFPDSSGSLKLWCQFFNIVSDSVLTWAKDQHLVGEVSRSAGDEGPAALAIVQASPTDCGLYRCTIQNEHGSASTDFRLSPEVLS-GFISREEGEVGEEIEMTPMVFAKGLADSGCWGDKLFGRLVSEELRGGGH--GLQKASRAKVIYGLEPIFESGRTCIIKVSSLLVFGPSSETSLLGRNYDVTIQGCKIQNMSREYCKIFAAETRAASGFGEVPEIIPLYLIYRPANNIPYATLEEDLGKPLQTYCSRQWSCAGAPAASSSLEPVQKCQTFQHWLYQWTNGSFLVTDLAGADWKMTDVEIATKLRGYQGLKESCFPALLDQFASSHQCNTYCEMLGLKPLKGPEGAHPQTKAKGSKSPSAGRKGSQLSPQPQKKGLPSPQGSRKSAPSSRATPQASQEATLQLLGQPPAQEGSSKAQGMR", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q924C5-1", "uniprot_id": "ALPK3_MOUSE", "id": "Q924C5-1", "name": "Alpha-protein kinase 3", "aln": "MGSRRAAGRGWGLGGRAGAGGDSEDDGPVWTPGPASRSYLLSVRPEASLSSNRLSHPSSGRSTFCSIIAQLTEETQPLFETTLKSRAVSEDSDVRFTCIVTGYPEPEVTWYKDDIELDRYCGLPKYEITHQGNRHTLQLYRCQEEDAAIYQASARNTKGIVSCSGVLEVGTMTEYKIHQRWFAKLKRKAAAKMREIEQSWKHGKEASGEADTLLRKISPDRFQR------------------------KRRLSGVEEAVLSTPVREMEEGSSAAWQEGE------TESAQHPGLGLINSFAPGEAPTNGEPAPENGEDEERGLLTYICEVMELGPQNSPPKESGAKKKRKDEESKPGEQKLELEKAEGSQ-------CSSENVVPSTDKPNSSRREK-STDTQPAQTQPRGRVARGPG---IESTRKTASVLGIQDKVQDVPAPAPAPVPAPALAPAPVPVPAPTPVPSRSSEQVYFSLKDMFMETTRAGRSQEEEKPPPPSTRVAGESPPGKTPVKSRLEKVPMVSSQPTSSMVPPPIKP-------LNRKRFAPPKSKVESTTTS----LSSQTSESMAQSLGKALPSASTQVPTPPARR--------------------RHGTRDSPLQGQTSHKTPG---------------------EALESPATVAPTKSANSSSDTVSVDHDSS--------------GNQGATEPMDTETQEDGRTLVDGRTGSRKKTHTDGKLQVDGRTQGDGAQDRAHASPR-----------------------------------TQAGEKAPTDVVTQGSERPQSDRSSWKNLVTQRRVDMQVGQMQAGERWQQD--------------PGDARIQEEE-----KETQSAAGSIPVAFETQSEQL-----------SMASLSSLPGALKGSPSGCPRESQAIECFEKSTEAPCVQERSDLMLRSEEAAFRS---HEDGLLGPPSGNRTYPTQLPPEGHSEHLGGQTHQR--------SEQEDSLSQCPKKEQPQEPLHVGLSGGHSTGLSQEVPAMPSLPG------TGLTSSLQEELPGTAASLHTNTDVPLPSRDQDFPSSAPTLQLGPGSPTQSHPPEAMATSSEGACAKEPNVDGRSSGTRSCDPGLIDSLKNYLLLLLKLSSP--------------------------------ETSEARAESQEVADTGGLTSSSTLVPTMEVAGLSPRTSRRILER---------------VENNHLVQSAQTLLLSPCTSRRLTGLLDREVQAGQQALAAAQCSRGPCPTP--LTIPAIVVGEE-------GSA---GEDSEER-----TSQESDKKGLLGEV-------EGHTVES-RTQEPCQEEAMPG----------------------EALTGLPAATPEELALGARRKRFLPKVRAGSDGEANKAEERESPTVSPRGPRKGLTPGSPG----TPGRERRSPTQARKASMLEVPGAEEEP-------------------------ATGDLVSRSKDSGLDSEP--------------AVDEGKQEALAKQRKAKDLLKAPQVIRKIRVEQFPDSSGSLKLWCQFFNIVSDSVLTWAKDQHPVGEVNRSAGDEGPAALAIVQASPTDCGVYRCTIQNEHGSASTDFCLSPEVLS-GFISREEGEVGEEIEMTPMVFAKGLADSGCWGDKLFGRLVSEELRGGGH--GLQKASRAKVIYGLEPIFESGRTCIIKVSSLLVFGPSSETSLLGRNYDVTIQGCKIQNMSREYCKIFAAEARAASGFGEVPEIIPLYLIYRPANNIPYATLEEDLGKPLQTYCSRQWGCAGAPAAASSSEALQKCQTFQHWLYQWTNGSFLVTDLTGADWKMTDVQIATKLRGYQGLKESCFPALLDQFASSHQCNTYCDMLGLKPLKGPEAAHPQAKAKGSKSPSAGRKGSQLSPQPQKKGLPSPQGSRKSAPSSRATLQASQAATVQLLGQPPVQDGSSKAQSMR", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q96L96-1", "uniprot_id": "ALPK3_HUMAN", "id": "Q96L96-1", "name": "Alpha-protein kinase 3", "aln": "MGSRRAPSRGWGAGGRSGAGGDGEDDGPVWIPSPASRSYLLSVRPETSLSSNRLSHPSSGRSTFCSIIAQLTEETQPLFETTLKSRSVSEDSDVRFTCIVTGYPEPEVTWYKDDTELDRYCGLPKYEITHQGNRHTLQLYRCREEDAAIYQASAQNSKGIVSCSGVLEVGTMTEYKIHQRWFAKLKRKAAAKLREIEQSWKHEKAVPGEVDT-LRKLSPDRFQR------------------------KRRLSGAQAPGPSVPTREPEGGTLAAWQEGE------TETAQHSGLGLINSFASGEVTTNGEAAPENGEDGEHGLLTYICDAMELGPQRALKEESGAKKKKKDEESKQGLRKPELEKAAQSR-------RSSENCIPSSDEPDSCGTQG-PVGVEQVQTQPRGRAARGPGSSGTDSTRKPASAVGTPDKAQKAPGPGP-------------------------GQEVYFSLKDMYLENTQAVRPLGEEGPQTLSVRAPGESPKGKAPLRARSEGVPGAPGQPTHSLTPQPTRP-------FNRKRFAPPKPKGEATTDSKPISSLSQAPECGAQSLGKAPPQASVQVPTPPARR--------------------RHGTRDSTLQGQAGHRTPG---------------------EVLECQTTTAPTMSASSSSDVASIGVSTS--------------GSQGIIEPMDMETQEDGRTSANQRTGSKKNVQADGKIQVDGRTRGD----GTQTAQR-----------------------------------TRADRKTQVDAGTQESKRPQSDRSAQKGMMTQGRAETQLETTQAGEKIQEDRKAQADKGT-----QEDRRMQGEKGMQGEKGTQSEG-SAPTAMEGQSEQE-----------VATSLGPPSRTPKLPPTAGPRAPLNIECFVQTPEGSCFPKKPGCLPRSEEAVVTASRNHEQTVLGPLSGNLMLPAQPPHEGSVEQVGGERCRGPQSSGPVEAKQEDSPFQCPKEERPGGVPCMDQGGCPLAGLSQEVPTMPSLPG------TGLTASPKAGPCSTPTSQHGSTATFLPSEDQVLMSSAPTLHLGLGTPTQSHPPETMATSSEGACAQVPDVEGRTPGPRSCDPGLIDSLKNYLLLLLKLSST--------------------------------ETSGAGGESQVGAATGGLVPSATLTPTVEVAGLSPRTSRRILER---------------VENNHLVQSAQTLLLSPCTSRRLTGLLDREVQAGRQALAAARGSWGPGPSS--LTVPAIVVDEEDPGLASEGASEGEGEVSPEGPGLLGASQESSMAGRLGEAGGQAAPGQGPSAES-IAQEPSQEEKFPG----------------------EALTGLPAATPEELALGARRKRFLPKVRAAGDGEATTPEERESPTVSPRGPRKSLVPGSPG----TPGRERRSPTQGRKASMLEVPRAEEEL-------------------------AAGDLGPSPKAGGLDTEV--------------ALDEGKQETLAKPRKAKDLLKAPQVIRKIRVEQFPDASGSLKLWCQFFNILSDSVLTWAKDQRPVGEVGRSAGDEGPAALAIVQASPVDCGVYRCTIHNEHGSASTDFCLSPEVLS-GFISREEGEVGEEIEMTPMVFAKGLADSGCWGDKLFGRLVSEELRGGGYGCGLRKASQAKVIYGLEPIFESGRTCIIKVSSLLVFGPSSETSLVGRNYDVTIQGCKIQNMSREYCKIFAAEARAAPGFGEVPEIIPLYLIYRPANNIPYATLEEDLGKPLESYCSREWGCAEAPTASGSSEAMQKCQTFQHWLYQWTNGSFLVTDLAGVDWKMTDVQIATKLRGYQGLKESCFPALLDRFASSHQCNAYCELLGLTPLKGPEAAHPQAKAKGSKSPSAGRKGSQLSPQPQKKGLPSPQGTRKSAPSSKATPQASEPVTTQLLGQPPTQEEGSKAQGMR", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M9PZ45-1", "uniprot_id": "A0A8M9PZ45_DANRE", "id": "A0A8M9PZ45-1", "name": "non-specific serine/threonine protein kinase", "aln": "MSSRRLINRSLSTDGRSYSSGYSDISSQSRRAG--CRSYLSSVRSESSYAGHRLSQFKPSRSTLCSVMAQLTEEIQPTFESTLKSKAVSEETNVKFSCVVSGYPVPEVTWYKDDIQLDRYCGLPKYEISRDDKTHTLQIYNCSLDDAAIYQASAQNSRGIVSCSGVLEVGTMSEYKIHQNYFAKLKLRNENRRREQEETRRTGIETVPVSSEHIRMSSPERVQPNCEAHSPSENRGVEVDALGQTPSLGDRLSAPNQESAAVPHGISNSEEITNKEKDRQELTYIHDTVNNATSEQINEHVKKKVKISTERRKENRPNGRREEMVTESGTSVKETEVQMVSETEQRNKMDITDIKQKENLLVKADIGGSEETKKAQCAQIASTIKSRNKIDITNRKKTEEESLKVNKTAIEQSKRGALNSSVTESRNKTVIAKTKTTEKQLVMVNKSALRELKTASDVQMTPETETKSKNYVTNTKIYEKTAVKVNNNASEELKRTQNASAIEPKNKTDITERKTTEKLTEKLNKSVSEELKKVQDVPMTSSRNITDKTDIKQTENPSVNTNKSVSEESKRAQGAQMASVTESRNKMLNKVTKTTEETPVKVNKCASEELEISQSAKITSAMEHGNKVNITDTRKSDKLSANTNTKTSVTEESKNAQDAKIASVIESKAKMDVKDTIKSEKQSVYTDENVSKVSNKAQEAPGASVSAKAKVDITDTKTSEKQPVSTNKQGYGESKTVSGASETSGTATKAKMDKTNTKISEKHSVNPIKQVFGQSKKFQGSPETSVFESETKVDIIDTKTSQKQSVSTNKQGYGESKTVQGASETSVTESKAKVDITKTKTGEKHSVNPNKQLYGQSKKLQGASETSVFKSKTKVDIIDTKTNDKQPETIKESASESKKVLKPIPTQNNTLLKTSTTNQINKVVENPNPTKSSDTQLQESLENGNLRHADNKHVDFDDHRNRNQVGTRVKILPHSCGGNDVNVDTGERNVSGRPLRGSVVADTQTKPTEPLTHEDVLTHKEVAKELKEQPTLMHQATAGANVSASALQEQKLTAGDPSAASTKRSTLVTGPQNTQPSDKISSGHVSNKLQNGQVPTAMSPSLGDETLTNTCKKESKAENQLIKESDKPNSETRPASQQNMDENEINSNVQSSTSKEKLTAKSNHSTIKDIAAESAQICSDVIQQQTMNGSSIKETNDRELQRSSPIATDNVVKMNIKEQSNATTSEAPQKTYKEIQSYPIQKANDHSGPSTFLSQHSKASATEFTIPAIYITDVDSTSQNSTVEMRTEVNAVTSNVTNTSNRTDSINETTAVIESESLHNEKFDLSQNSQVSEVNKPDQPLLSQENPIQVLLNHRSSEKVASDFTTQKDDTIQNPNADRCIKSNESDLTETSDLTKTDLTFKTDPGSFIKLLRSAAFELEVSNRCSTFTAAPHTNYKDNNEREEEVSSAEVHTETCKVKIPLNNTGNRVFNSTQSELTTSTDQTTSFPKIKTDKSETGMAKFIEEANMDTFQGDKLKSQPASTSQSVSTSPLMTSLETQSPRLTRRTVLNDQPKPVGIENGKPKSTEKDKENQFKVPQVIRKIRPEVF-DASGHLKLWCQFFNIVSDSTIRWFKDEVEIAEIKRSAGDEAQVCLAIIKMSKRDSGVYRCTITNEYGKDSTEYHLSTEFLSNMFVREEHQEVGEEIEMTPLIFSKGLSDAGGWGSKFYGRVTTEEAQVGLG--CEHKTRRLKVIYGLDPVFESGSSCFMKVRSPIAYESREEIVLAERNLQITKQECRIQNLAREYFKIFAAETRVIESFGGVLEVIPLYFTYWPASSVPYATVEAELKGVYVRYCGLDR--SGSLVINEKSEVGQKCSSLQHWIHQWTSGNVLFSRLEGVDTILTNIGVAVRSKGYQGFPCEANLRVFEQFQIQHQCNYFCGLLNLRSLKTPETLQTPSRSKGSSSPLLQRRIADNSS--------SPQISRKATKSPKLSRKPNPQTST-------------------", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*** .*. . .**: :.* .: .. .. .**** ***.*:* :.:***: ...***:**::****** ** **:****::***:::*:*:*:*:*** ********* :************:::.: ****:*.* :*********:*::**************:******.:***** : : ** *:: : . . :* **:*.* ***. : ..* : : ::.. ::.::. **... :. . * ** : .: :. . . .: .*: ::* . : * . . *. . . : * :: : : .:. . : **. .:*: : . :. :. : * ...* . . . . : . . * : .: . * . : *: *. : : :. . . . ::* .* .: . .*.: .**.: . : : ..: .. ..:*. :. : .*..: . . * . :. : * :*.*. . .: : ...:. :... . *:.. :: : *::..* .. .* ..:: :.: : :*: :.. :: ::**: . : : : . *:: . . * .*. . .. * . * . : :. : .:. : . : . .** : . : *. :** : :. : :.:* .. .*.. : : .* .* : .: . :: .:* : ** : *:: * * .. :. *: : *... :. * . *:* : **:: *:. : . *..:. : .:. :*:.: : :: :.:: ..::: : : : : : *: :. *.: .. . :. .: *: .* . : . : ***. *.. : : :. *:* :. : . :: * ::. ** :. * . * . :: ..: ** .*. * .. : : ...* .. :.. :.: :.:*: :: :.* :: .: . . .*::: .:. : :. :. :. :: :*.******** * * *:** **********:***.: * **: :.*: ******. ..***:: * *.*:***** **:*. **:: **.*.** *: .*. **********::*:***:*:* **.*::**:.:** : * :*: : ******:*:**** :*::** * :.: . .* * ** ::* * *:***::*** ******:*. .** * *:****: * **..:****:* :* **. : : : . . * ***.::***::***.*..*.: * *.* :*:: :*.: :****: .. ::::* .**** :* :*.* .** ** :. :::***.** *: :: *. *** :**:: *.: : :.. .: ", "identical_positions": 398, "similar_positions": 559, "identity": "19.81%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121101-4", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8R4Z9-1", "uniprot_id": "MFN1_RAT", "id": "Q8R4Z9-1", "name": "Mitofusin-1", "aln": "----------------------------------------------------------------------------------------------------------------MAETVSPLKHFVLAKKAITAIFGQLLEFVTEGSHFVEATYRNPELDRIATEDDLVEIQGYRNKLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDK----------------AYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVHVFWPKAK----CALLRD---DLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVSPLEARNRIFFVSAKEVLNSRMNKAQGMPEGGGALAEGFQARLQEFQNFEQTFEECISQSAVKTKFEQHTIRAKQILDTVKNILDSVNVAAAEKRVYSMEEREDQIDRLDFIRNQMNLLTMDVKKKIKEVTEEVANKVSCAMTDEICRLSVLVDEFCSEFHPTPSVLKVYKSELNKHIEDGMGRNLADRCTSEVNASILQSQQEIIENLKPLLPAG--IQNKLHTLIPCKKFDLSYDLNCHKLCSDFQEDIVFRFSLGWSSLVHRFLGSTN--AQRVLLGLSEPIFQVPRSLASTPTAPSNPAAPDNAAQEELMITLITGLASLTSR---TSMG------IIVVGGVIWKTVGWKLISVTLSMYGALYLYERLTWTTRAKERAFKQQFVNYATEKLQMIVKFTSANCSHQVQQEMATTFARLCQQVDVTQKHLEEEIARLSKEIDQLEKIQNNSKLLRNKAVQLERELENFSKQFLHPSSGES", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q811U4-1", "uniprot_id": "MFN1_MOUSE", "id": "Q811U4-1", "name": "Mitofusin-1", "aln": "----------------------------------------------------------------------------------------------------------------MAETVSPLKHFVLAKKAITAIFGQLLEFVTEGSHFVEATYRNPELDRIASEDDLVEIQGYRNKLAVIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHTTNCFLSVEGTDGDK----------------AYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVHVFWPKAK----CALLRD---DLVLVDSPGTDVTTELDIWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVSPSEARNRIFFVSAKEVLNSRKHKAQGMPEGGGALAEGFQARLQEFQNFEQTFEECISQSAVKTKFEQHTIRAKQILDTVKNILDSVNVAAAEKRVYSMEEREDQIDRLDFIRNQMNLLTLDVKKKIKEVTEEVANKVSCAMTDEICRLSVLVDEFCSEFHPTPSVLKVYKSELNKHIEDGMGRNLADRCTNEVNASILQSQQEIIENLKPLLPAG--IQNKLHTLIPCKKFDLSYDLNCHKLCSDFQEDIVFRFSLGWSSLVHRFLGSTN--AQRVLLGLSEPIFQVPRSLASTPTAPSNPAAPDNAAQEELMITLITGLASLTSR---TSMG------IIVVGGVIWKTVGWKLISVTLSMYGALYLYERLTWTTRAKERAFKQQFVNYATEKLQMIVSFTSANCSHQVQQEMATTFARLCQQVDVTQKHLEEEIARLSKEIDQLEKIQNNSKLLRNKAVQLESELENFSKQFLHPSSGES", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q8IWA4-1", "uniprot_id": "MFN1_HUMAN", "id": "Q8IWA4-1", "name": "Mitofusin-1", "aln": "----------------------------------------------------------------------------------------------------------------MAEPVSPLKHFVLAKKAITAIFDQLLEFVTEGSHFVEATYKNPELDRIATEDDLVEMQGYKDKLSIIGEVLSRRHMKVAFFGRTSSGKSSVINAMLWDKVLPSGIGHITNCFLSVEGTDGDK----------------AYLMTEGSDEKKSVKTVNQLAHALHMDKDLKAGCLVRVFWPKAK----CALLRD---DLVLVDSPGTDVTTELDSWIDKFCLDADVFVLVANSESTLMNTEKHFFHKVNERLSKPNIFILNNRWDASASEPEYMEDVRRQHMERCLHFLVEELKVVNALEAQNRIFFVSAKEVLSARKQKAQGMPESGVALAEGFHARLQEFQNFEQIFEECISQSAVKTKFEQHTIRAKQILATVKNIMDSVNLAAEDKRHYSVEEREDQIDRLDFIRNQMNLLTLDVKKKIKEVTEEVANKVSCAMTDEICRLSVLVDEFCSEFHPNPDVLKIYKSELNKHIEDGMGRNLADRCTDEVNALVLQTQQEIIENLKPLLPAG--IQDKLHTLIPCKKFDLSYNLNYHKLCSDFQEDIVFRFSLGWSSLVHRFLGPRN--AQRVLLGLSEPIFQLPRSLASTPTAPTTPATPDNASQEELMITLVTGLASVTSR---TSMG------IIIVGGVIWKTIGWKLLSVSLTMYGALYLYERLSWTTHAKERAFKQQFVNYATEKLRMIVSSTSANCSHQVKQQIATTFARLCQQVDITQKQLEEEIARLPKEIDQLEKIQNNSKLLRNKAVQLENELENFTKQFLPSSNEES", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AC58H9X0-1", "uniprot_id": "A0AC58H9X0_DANRE", "id": "A0AC58H9X0-1", "name": "", "aln": "---------------------------------------------------------------------------------------------------------------MEQDGVSPLQHFVVAKKTISALFHQLLEFVKEGSDFVEDTWRSEDLDNVAEEDQCLQIQTCFRKLTVIKDVLDRRHMKVAFFGRTSNGKSTIINAMLRERVLPSGIGHTTNCFLSVEGTDGEQ----------------AYLTTEDSEERKGIETVNHLAHALHMNRNQDSGCLVRVFWPKTK----CVLLRD---DLVLMDSPGIDVTSELDSWIDKFCLDADVFVLVANSESTIMNTEKHFFHKVNERISKPNIFILNNRWDASVLEPEYLEDVRKQHMDRCVSFLVDELKVVDLNKAPDRIFFVSAKEVLSARIHRAQGMPETGGALAEGFQERLMEFQSFERTFEEFISQSAVKTKFEQHTIRAWQIIESVKAIMDAINISSAEKKVFSLEDREALMDRLEFVRNQLNFITEDIKDKIKVVSDEVAAKVSSALEEEMRCLSVLVDEFCSEFIPAPNALALYKTKLVSYVEERMVKNLELRCSSSINGCVLSSQRDIMDTLRPLLPPA--ARAQLH--LPSRRFTMTYDLNLTSLGADFTEDIDFHFSLGLTSLVNRFLGPAN--AKQALS-LLEQKLKLTSSSAHTGSR----------GHEDLALSMASGLLSLTSR---ASLAPVGQKRLALYKLLVWRAVGWRVIVLSVSLYSFLYLYERLTWTNSSKERALKQQYVDHTTQRLQAVAHIISGDSGQQVQQEMVAVFARMCQQVDKSEMELETEIRRLSARIQRLESVQRRSKTLRHKATDLESQLERFSAQYLQIDH---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q7YU24-1", "uniprot_id": "MARF_DROME", "id": "Q7YU24-1", "name": "Transmembrane GTPase Marf", "aln": "----------------------------------------------MAAYLNRTISMVTGQTGPADDDRHASS-TDTVDKSGPGSPLSRFNSSLQQSGSTMAANLLPESRLYQSNDKSPLQIFVRAKKKINDIYGEIEEYVHETTTFINALHAEAEIVDKAER---ELFESYVYKVAAIREVLQRDHMKVAFFGRTSNGKSSVINAMLREKILPSGIGHTTNCFCQVEGSNGGE----------------AYLMTEGSEEKLNVVNIKQLANALCQEKLCES-SLVRIFWPRER----CSLLRD---DVVFVDSPGVDVSANLDDWIDNHCLNADVFVLVLNAESTMTRAEKQFFHTVSQKLSKPNIFILNNRWDASANEPECQESVKSQHTERCIDFLTKELKVSNEKEAAERVFFVSARETLQARIEEAKGNPPHMGAIAEGFQIRYFEFQDFERKFEECISQSAVKTKFQQHSSRGKSVSGDMKSMLDNIYERITIFRNLKQDQKNLLTERIQGTETQMMQVTREMKMKIHNMVEEVEEKVSKALNEEIWRLGVLIDEFNMPFHPERLVLNIYKKELNAHVESGLGSNLRARLSMALAMNVESAQTEMTDRMHALVPNEQLLATSTKMVVRTQPFEMLYSLNCQNLCADFQEDLEFKFSWGIAAMIQRFTGKVRERSKKGQPALVNRQSSIGHSVS-TPTTTPVEATPVCLLPAPVVAGITPEQLSLISRFAVSSIGSQGTVGGLVVAGVMLKTIGWRVLVGVGALYGCIYLYERLSWTNSAKERTFKSQYVRHATKKLKMIVDLTSANCSHQVQQELSSTFARLCRTVDTATTDMNDELKTLDSQLNILEANQKQLKLLRNKANYIQNELDIFEHNYISPQ----", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "P38297-1", "uniprot_id": "FZO1_YEAST", "id": "P38297-1", "name": "Mitofusin FZO1", "aln": "MSEGKQQFKDSNKPHKDSTDQDDDAATIVPQTLTYSRNEGHFLGSNFHGVTDDRTTLFDGEEGRREDDLLPSLRSSNSKAHLISSQLSQWNYNNNRVLLKRSILKTQAFMDQLQEENNIRPIFIAANDEREKLHVLQLNIKLDGQYNTKEKNGFNIEKKALSKLFHSQIVSVTNHLNALKKRVDDVSSKVFITGDVNTGKSALCNSLLKQRLLPEDQLPCTNVFSEILEARENDGIEEVHAIPLNIAPTLKEAIDMYSIQNPKTYEIHTLKELPDLVPQNGKYALLKIYIKDDKRPASTSLLRNGTVDISLIDSPGLNMDSLQTAEVMSRQEEIDLVIFVVNAENQLTLSAKEFISLASR--EKKLMFFVVKKFDKIRDKQRCKELILKQ---------IRDLSPETYKRAADFVHFVSKNGDELPHYHNENDNEDHGDRKPDDDPYSSSDPDPDFDSLEDSLRNFVLKKRSLSKLLPAKTYLS--KLLSDIIMISKSNMKMYS-EEEIKINEQLETLRPEILSARAKCNDLTTSVDQMAEQTITMTYNNTKEALLNALDVPLHEYPKYQGLGQIYDFIFS------TEAFIANQIDESIGSSELFAKQKTDLLVKKIYEIG--KNELGDDFMCERVFRSELMFRKRKHLIGKRLKVSLSITDLFAPTWKGFLSYLS-WQKPVTAPLPDIEGQTNEGQIGLMKYLGLKNYPLTQYWSRPSLLFTSKIPTLTLY----FLG-----STKVVGNIILNGIKLSSWSSLKKLSVPVIVVGSLLGLTYLIHDLPRALPMNLSIKYKRKLQELDYIHLNAQRTSNEVRDVLRVPTREILRSCEIIMDKKQITKKELENKKESNLLSIKFFQSLYEGTVAQKLMVEEINLDID--", "tax_id": 559292, "tax_name": "Baker's yeast" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : . *: *:. :. : : : . : :: : . :. ** : * ...***:: *::* :::**.. ** * .: : . * :. :: * . .*:::: : ***: *: ::**** :: : : . : *:.::* *:*. : : *.*: ... .* :*:: :::* : . * : * :*. .* : :.*** . .: .. :. .:. : : :*: : : .:*.: .: . * : * : : . ::. :::: . :: . : : : . .:: : : * :* : :*. : : : : :: . :: : . : : * :. . . .: : :: :. : * . : * : . . . : . :: :. : :: . : : : : * . . : : : : : : . . * .: . *: .: : : . : .. . :: : : : : . ", "identical_positions": 55, "similar_positions": 211, "identity": "6.19%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121105-12", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A0A8I6AJS5-1", "uniprot_id": "A0A8I6AJS5_RAT", "id": "A0A8I6AJS5-1", "name": "Rho GTPase-activating protein 33", "aln": "-------------------------------------MLQAQKQSDPILP---------------WGASWAGRGQTLRARSTDSLDGPGESSVQPVPPTGGPGTKGKPG----------KRLSAPRGPFPRLADCAHFHYENVDFGHIQLLLSPERE-----------------GPSLSG--ENELVFGVQVTCQ-GRSWPVLRSYDDFRSLDAHLHRCIFDRRFSCLPELPPPPEGARAAQMLVPLLLQYLETLSGLVDSNLNCGPVLTWMELDNHGRRLLLSE---EASLNIPAVAAAHVVKRYTAQAPDELSFEVGDIVSVIDMPPTEDRSWWRGKRG------FQVGFFPSECVELFTERPGPGLKADAEGP----LCGIPAPQGISSLTS--AVPRPRGKLAGLLRTFMRSRPSRQRLRQRGILRQRVFGCDLGEHLSNSGQDVPQVLRCCSEFIEAHGVVDGIYRLSGVSSNIQRLRHEFDSERIPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEE--ERLVRVHDVIQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLLRSMELESVGLGGAAAFREVRVQSVVVEFLLTHVEVLFSDTFTSAGLDPAGRCLLPRPKSLAGSSPSTRLLTLEEAQARTQG---RLGTPTEPTTPKTPASPVERRKRERVEKQRKPGGSSWKTFFALGRGPSIPRKKPLPWLSGSRAPPQPSGS-RPDTVTLRSAKSEESLSSQASGAGLQRLHRLRRPHSSSDAFPVGP---------------APAGSCESLSSSSSSSSSSS---SSSSSESSAAGLGPLSGSPSHRTSAWLDDGDELDFSPPRCLEGLRGLD--------------FDPLTFRCS------------------------------------------------------------------SPTPG-DPAPPASPAPPASASAFPPRATPQALSPHGP-KPASPTALDISEPLAVSVPPAVLELLG-AGGAPASATP---------------------TPALSPNPGLRPHLIPLLLHGAEAQLSDTCQQEISSKLAPTRGAPGQHSPGGMDSPLLPP--------------ALSLLRPGGAPPPPPKNPARLMALALAERAQQVAEQQS----QQGQGGTPPAPLSPFRRSLSLEVGG-----------------------------------------------EP-------------------VGTSGSGLHPPSLAHPGAWAPG-----------PTPYLPRQQSDGSLVRSQR--------------------------------------------------------------------PLGTSR--------------RGPRGPSQVSAHLRASGAYRDTPEMAAQS----PCSIPSQGSNPSFLS-TPRECLPSFLGVPKQG--------LYSLGPPSFPPNSPAPVWRNSLGAPPALD---------------RGEN-LYYEIGVGEGT-----YSGPSRSWSPFH------SMPPDRLNASYGMLGQS---------PPLHRSPDFLLNYP-----PPPSCFPPDPLTHSVSQHLARRPTR----------------------------------------------------------PEPLYVNLALG-PRGPSPAS--------------------SSSSSPP----------------------------------------AHPRSRSDPGPP-----------------VPRLPQKQR-----------APWGPHNPHRVPGPWG-SPEPFLLYRAAP----------PSYGRGGEVR-GSLYRNGG----------------------------HRGEGAGP----------PPPYP---------------------------------------------------------------------------------------TPSWSLNSEGQTRSYC----", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q80YF9-1", "uniprot_id": "RHG33_MOUSE", "id": "Q80YF9-1", "name": "Rho GTPase-activating protein 33", "aln": "-------------------------------------MLQAQKQSDPILP---------------WGASWAGRGQTLRARSTDSLDGPGEGSVQPVPTTGGPGTKGKPG----------KRLSAPRGPFPRLADCAHFHYENVDFGHIQLLLSPERE-----------------GPSLSG--ENELVFGVQVTCQ-GRSWPVLRSYDDFRSLDAHLHRCIFDRRFSCLPELPPPPEGTRAAQMLVPLLLQYLETLSGLVDSNLNCGPVLTWMELDNHGRRLLLSE---EASLNIPAVAAAHVVKRYTAQAPDELSFEVGDIVSVIDMPPTEDRSWWRGKRG------FQVGFFPSECVELFTERPGPGLKADADSP----LCGIPAPQGISSLTS--AVPRPRGKLAGLLRTFMRSRPSRQRLRQRGILRQRVFGCDLGEHLSNSGQDVPQVLRCCSEFIEAHGVVDGIYRLSGVSSNIQRLRHEFDSERIPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEE--ERLVRVHDVIQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLLRSMELESVGLGGAAAFREVRVQSVVVEFLLTHVEVLFSDTFTSAGLDPAGRCLLPRPKSLAGSSPSTRLLTLEEAQARTQG---RLGTPTEPTTPKTPASPVERRKRERAEKQRKPGGSSWKTFFALGRGPSIPRKKPLPWLGGSRAPPQPSGS-RPDTVTLRSAKSEESLSSQASGAGLQRLHRLRRPHSSSDAFPVGP---------------APAGSCESLSSSSSSSSSSS---SSSSSESSAGGLGPLSGSPSHRTSAWLDDGDDLDFSPPRCLEGLRGLD--------------FDPLTFRCS------------------------------------------------------------------SPTPG-DPAPPASPAPPASASAFPPRATPQALSPHGPTKPASPTALDISEPLAVSVPPAVLELLG-AGGTPASATP---------------------TPALSP------HLIPLLLRGAEAQLSDTCQQEISSKLAPTRGAPGQQSPGGMDSPLLPP--------------PLPLLRPGGAPPPPPKNPARLMALALAERAQQVAEQQS----QQEQGGTPPAPHSPFRRSLSLEVGG-----------------------------------------------EP-------------------VGTSGSGIHPPSLAHPGAWAPG-----------PPPYLPRQQSDGSLVRSQR--------------------------------------------------------------------PLGTSR--------------RSPRGPSQVSAHLRASGAYRDAPEMAAQS----PCSVPSQGSNPSFFS-TPRECLPPFLGVPKQG--------LYSLGPPSFPPSSPAPVWRNSLGAPSALD---------------RGEN-LYYEIGVGEGTS----YSGPSRSWSPFR------SMPPDRHNASYGMLGQS---------PPLHRSPDFLLSYP-----PPPSCFPPEHLTHSVSQRLARRPTR----------------------------------------------------------PEPLYVNLALG-PRGPSPAS--------------------SSSSSPP----------------------------------------AHPRSRSDPGPP-----------------VPRLPQKQR-----------APWGPHTPHRVPGPWG-SPEPFLLYRPAP----------PSYGRGGEVR-GSLYRNGG----------------------------HRGEGAGP----------PPPYP---------------------------------------------------------------------------------------TPSWSLHSEGQTRSYC----", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "O14559-1", "uniprot_id": "RHG33_HUMAN", "id": "O14559-1", "name": "Rho GTPase-activating protein 33", "aln": "----------------------------------------------------------------------------MVARSTDSLDGPGEGSVQPLPTAGGPSVKGKPG----------KRLSAPRGPFPRLADCAHFHYENVDFGHIQLLLSPDRE-----------------GPSLSG--ENELVFGVQVTCQ-GRSWPVLRSYDDFRSLDAHLHRCIFDRRFSCLPELPPPPEGARAAQMLVPLLLQYLETLSGLVDSNLNCGPVLTWMELDNHGRRLLLSE---EASLNIPAVAAAHVIKRYTAQAPDELSFEVGDIVSVIDMPPTEDRSWWRGKRG------FQVGFFPSECVELFTERPGPGLKADADGP----PCGIPAPQGISSLTS--AVPRPRGKLAGLLRTFMRSRPSRQRLRQRGILRQRVFGCDLGEHLSNSGQDVPQVLRCCSEFIEAHGVVDGIYRLSGVSSNIQRLRHEFDSERIPELSGPAFLQDIHSVSSLCKLYFRELPNPLLTYQLYGKFSEAMSVPGEE--ERLVRVHDVIQQLPPPHYRTLEYLLRHLARMARHSANTSMHARNLAIVWAPNLLRSMELESVGMGGAAAFREVRVQSVVVEFLLTHVDVLFSDTFTSAGLDPAGRCLLPRPKSLAGSCPSTRLLTLEEAQARTQG---RLGTPTEPTTPKAPASPAERRKGERGEKQRKPGGSSWKTFFALGRGPSVPRKKPLPWLGGTRAPPQPSGS-RPDTVTLRSAKSEESLSSQASGAGLQRLHRLRRPHSSSDAFPVGP---------------APAGSCESLSSSSSSESSSSES-SSSSSESSAAGLGALSGSPSHRTSAWLDDGDELDFSPPRCLEGLRGLD--------------FDPLTFRCS------------------------------------------------------------------SPTPG-DPAPPASPAPPAPASAFPPRVTPQAISPRGPTSPASPAALDISEPLAVSVPPAVLELLG-AGGAPASATP---------------------TPALSPGRSLRPHLIPLLLRGAEAPLTDACQQEMCSKLR---GAQGPLGP-DMESPLPPP--------------PLSLLRPGGAPPPPPKNPARLMALALAERAQQVAEQQS----QQECGGTPPASQSPFHRSLSLEVGG-----------------------------------------------EP-------------------LGTSGSGPPPNSLAHPGAWVPG-----------PPPYLPRQQSDGSLLRSQR--------------------------------------------------------------------PMGTSR--------------RGLRGPAQVSAQLRAGGGGRDAPEAAAQS----PCSVPSQVPTPGFFSPAPRECLPPFLGVPKPG--------LYPLGPPSFQPSSPAPVWRSSLGPPAPLD---------------RGEN-LYYEIGASEGSP----YSGPTRSWSPFR------SMPPDRLNASYGMLGQS---------PPLHRSPDFLLSYP-----PAPSCFPPDHLGYSAPQHPARRPTP----------------------------------------------------------PEPLYVNLALG-PRGPSPAS--------------------SSSSSPP----------------------------------------AHPRSRSDPGPP-----------------VPRLPQKQR-----------APWGPRTPHRVPGPWG-PPEPLLLYRAAP----------PAYGRGGELHRGSLYRNGG----------------------------QRGEGAGP----------PPPYP---------------------------------------------------------------------------------------TPSWSLHSEGQTRSYC----", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0A8M2B5A9-1", "uniprot_id": "A0A8M2B5A9_DANRE", "id": "A0A8M2B5A9-1", "name": "", "aln": "-------------------------------------MQRRVTLSGAHWVRKCAMFVRTMSLADMSGFLPRGEQLAIKARSTDNLDSSGEPGTRSVGTTAN--LKGKMS----------KRLSVVKGHFPKLVDCAHFHYENVDFGSIELQFANEQS-----------------DASWTSGSAKDLVFLVQVSCQ-GKTWMVRRSYEEFRTLDAHLHQCIYDRRYSQLLALPALCEIGDRLEILTPLLSEYLNRLTMIVDNKLNCGPVLTWMEIDNHGNRFLLKE---EASLNVPAIAAAHVIKRYTAQASDEISIEVGDILSVIDMPPKEDTTWWRGKHG------FQVGFFPSECVELINEKMPQSVSAPVSKQEVDLMSSKPGATNTTGPSSPTSVSKKHGKLMGFLRTFMKSRPTKQKLKQRGILKERVFGCDLGEHLLNSGLDVPQVLTSCSEFIEKHGVVDGIYRHSGVSSNIQKLRHEFDSENVPDLTKDVYMQDIHCVGSLCKLYFRELPNPLLTYQLYDKFAECMGEMTEE--ERMVKVHDVIQQLPPPHYRTLEYLIRHLAHLATCSAETNMHIKNLAIVWAPNLLRSKEIEAAGLTGADPFKEVRIQSVVVEFLLSNVEVLFSDSFTSVGRFNAARQSLTRPKSFVS----TRLLSLEEAQARTQAPLLLQGSPHHAIGQFHTVLDLPVDKRKRGMKVRKSAGGSWKTFFAIGKPGAVGRRKPARITSLFQPTTSHAGC-RVDSVTLRSAKSEESLSSQHSGAGQGKIQRLRRPRSSSDGLSLAASVDPQLLPQNSPSKIHPSRSYDSLLPEETRDADEE---EENEDEEDEEGVYMLPDFSQEPPSSWIT-EDVIDFSPTFLEDGPIGLGGTGGAPSGRESPPAAAPPPYRCLSHQGHHARSGSQRSITEDPDSVLNQSEAAARRSLILAAAAPPQQVFCQHRPSNAPANTTQSGESNLSPSHA-QTPAPATSAPPSQPPQERRSFTRKVVHALSPKAPKSP-PLDISDPIAISVPAKVLEMIGGRAGELQSGLP---------------------SSGPPQ----PPQMISMLLRSCDFQLTESCQQELSSKLGPIAKIKG--------PSILGP--------------TGVPLPSQQPPAPPPKNPARLMALALTESANKALRQGASPPYRPRQSAASPEKDIRFQRSLSADAGALLSSDPNQIYSTVRPLSVWKTEGGDGDDEEDDEGAAAEKAADKSHGTEPRSPPGQDIGTLSSNSSVSDSGTTNSELSAASSSEDNERTPSPIYKNEEPTSPPQPLISSPPSSSDLVPSQRKPPAYGRQFSAPQLQQEKSSGPSKPATQPHTQLLHSKSESSPLAQVRAFQPTRPKVPPKPPDLAPLRAPLSQTDRHDYMRRSLDASRIRRLAGPQQVNTPLSRAFSERISSTSDMLSR-YHAARMASQAAQVAHLPQQQAQSTPIRPVVPSSEDPSKMENFYYEIGAPEHPQVPPSYARHSYQNMKPDLEGNLRLTDPANQRPISRGYPPPYNSQGAGGGRSTQLWSSEATRAWAAAHSHSHSFSFSHSHHRSQDGSSGHPPHPR-----PQRQTSSSVRLSRSEVHPLPASTGSSTGMVPLSVHQRSLHRPHRSPSADHTASQLHPYFENGKVCYRYFEASRPEDLQLNLHEQAVVKTSQASPVQGITKDQPEPIYVNYPFTNPPGSGVNSKGWATTDLDENDYHASETQEAPSKSPPDDKQKHLEQESPTADFDNPSQNDLSSDSKMINIALSASTAMHFRSRSDPQSASSETAHVLTGKEIASLLIEKLAEDEREGPSVPSSTSSSPHIEHPPNPYPSQHQQPPPAYNVYTPGPSRGRFEGQVPPREGSGPFQRQDPLRRSSGGQYRQAFDVMPSGDQVLKFYRSQDFIPGAQGESTTPNPYPPRPYYQDPPYPNWGPQGLPDSSHTCTPPTVAFSNLALGSTRGYAPQTVANQYNQFPYQSGPVLPQYPNTPRRDVVLDPSLRPPGLRNQRGLNRQGSLPGPNWTIRTEGQTRSYC----", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VIS1-1", "uniprot_id": "CDGAP_DROME", "id": "Q9VIS1-1", "name": "GTPase-activating protein CdGAPr", "aln": "MSDKVSTSLAAQLHSHALASAEAGGIGGVNGGPIACHASTDKDAQAPPLQFEMDAPAAAISAQLNFKIVPADSLPGLSYQDMFASMNTSQISNASTESSCSPPIQGAVPPPKPSRHMAVQPLNSKSCRFPKLEECAHFHYERVQLGPLSVQLLDDKSEHMGSSIASQSLGGDLPHSSLRSFSPESCWFIIRVCPQRCEPFLIKRSFENMQLLDEMLHRCVYDRKISGLRNMEELAAELPSESDVEYAVAKYLERFSKIASDSLTCGTILTWLQLDNKGRRLPLADGETQRTINTPAVGAAYGVRRYQAQAPDEINIEVGDMISVIDMPSPAESIWWRGKKSHLQKSLYEVGFFPQSCVATIGDKVPRNFPMPAPLVG------------HLDASPTKPVLRKHGKLIAFFRSFILSRPSRRRLKQSGIYRERVFNCDLSEHLLNSGQDIPMVLRSCAEFIENYGVIDGIYRLSGITSNIQRLRRAFDEERVPDLGNPEMKQDIHAVSSLLKMYFRELPNPLCTYQLYDNFVEAIQVKADEADERLRLMKETVLKLPPPHYRTLKYLAEHLYKVSQHHGRTGMTDKNLAIVWAPNLLRSPALESG---GVAALRGVGVQAVVTEYLIRNCHNIFDALDDHPARHSMVASATAAAANAAGGELRLESLTDCESLLVEQREQDQSLGVVERPKSLSTGGAKLISLEEAQERHSRVEGADLKQSLPISMLTSASSNAASNIGSYIEVGGGPSSLPDKYHTVLSAPRSWQKRKPDKTPSWKSIFSRSQRQGNPDPGQKITTDVKDSVASRVSFVQASHAHASKELTKHDKPKSIELLETTSNERDPKPMDLCIRSNSIDSLRTVGHSRSVSHDSYFDLLQSPQRGHMTTCPSRELSELGLNFDREEPEMRIFS--------------------------------------------------------ESESLVSSPRVGKENVPPASGSATRRIMRARPEDFSSQTNSVNPSPKKQPRLNLLSPSSARTMPPPPLSAPGTASSSCGHESGGAENCCKRYKLEDQLCDIQFIDCGTPENVPTTQQQFASVEVHPPPKPARANQSPISSSNGASVGSSSSSTRYSYPSVQLGAKRKEQQDAKERFSYQGTFTQPGQKQESSAPRPVHSTNNGATLRKPRVEPVEDGQIKLHVPTPTTPARSPRYSLLLCDTESSDNSSAVNTPQYDMEPLMLTSAMSG---------------------VSGVSSNVQQQQLLLGVDASSSYLGSSHESLGQNINNHHDAEQRDMNALKRELSLDLNPLQPRLPQPANRAATLP----------------------VKDQLQAAAAAMCSSPNNSNFTDNTSQSVTPSEYGYQHLQRQLSMHSLLATDESSPVYEDFEQTPVKMVPSPIKSTISITYKSPEKEKKPSAILETNFDENTVYEQVKLFRNSVTEVNQMLHERSSLKQIAEEEQHDGGAYKAAEMTQQLLQLEQEHHDHEEQQEKEPEDEEQSQLLYENIELRKPKTVYENLRGEEMKFITEEQKPNVDRIELDSLDSLPDNMEHEQSSPSKSPTFSVKELANKFESSPVEQLPNFDFSVRGGSMKKPNELSVPKTMPAPVPLKKLNSSAQKITR---------------------------------------------------SLDENAFVREFGGKQLQDLSLSNKLPEVMSEVNSRRKSFDFTRPKTLNPPKRLPGMSITEEICQKRVGEMEAITPTTENRISLIQQNNMPKEQQSSANQFLPPAGRKNVLTGVVLDRERIDKIKEERRQQLTQKYYG--DTLKSRSRTELNSEDNFPAAESLRIKSKSRGD------MHALQKDIDMNLKQLSRVTGGGSECTLHTG-----------------LSQGNGQEHLGQQRVRRISDEKNQNCDTSNGGVSGITSTSLLSVKTTAQKYGSTSKTPAN--------------------KFERSQPMPRDRLQRNSLAESNAGTNNREKISPQFSIRDVTAMFESRSQNQ", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " : :. ...: . . .: . :* : *. **:* :*******.*::* :.: : ::. .* . :. * ::* * ..: : **::::: ** **:*::**: * * : . : : :**: :: :....*.**.:***:::**:*.*: * : : ::* **:.**: ::** ***.**:.:****::******. : *****:. ::*****..** : :: .. . . :. .* : :*** .::*:*: ***::::*:* ** ::***.***.*** *** *:* ** .*:**** :**:***** **::****:**: **.*.:*:* ****.*.** *:********* *****.:* *.: :* **: :::.: :*********:** .** ::: ..*.* :************* :*: *. .:: * :*:**.*:*: : . :*. . . . . .. . *: *: * . . : : : *.. * :.:. : . . . . :. ..* :.:* :. ..: : : : * :* ... . : . : : ..* .. .: . ... : . .: .. . : * . * . ** . : .**: :.. . . .* .* :* . * ::*. *. * .. . . : :. : : : *. :.*. . . . . ... .*.: . : :. :.* : *. .. *:: . . . . * . . .. : .: : : .* : . : : . : .* : : . * . :. * * . . .: .: .. . . . ... :. . . : .. : . . :.: : . . . . : .** . :* :: . : :: :..* . : . .. . . . . * * * :*:. *.:::. . ", "identical_positions": 238, "similar_positions": 381, "identity": "11.59%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121105-13", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8TEQ0-1", "uniprot_id": "SNX29_HUMAN", "id": "Q8TEQ0-1", "name": "Sorting nexin-29", "aln": "MSGSQNND-KRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGLKRSRGLALTAAAIKQAAGFASKTETEPVFWYYVKEVLNKHELQRFYSLRHIASDVGRGRAWLRCALNEHSLERYLHMLLADRCRLSTFYEDWSFVMDEERSSMLPTMAAGLNSILFAINIDNKDLNGQSKFAPTVSDLLKESTQNVTSLLKESTQGVSSLFREITASSAVS--ILIKPEQETDPLPVVSRNVSADAKCKKERKKKKKVTNIISFDDEEDEQNSGDVFKKTPGAGESSEDNSDRSSVNIMSAFESPFGPNSNGSQSS--NSWKIDSLSLNGEFGYQKLDVKSIDDEDVDENEDDVYGNSSGRKHRGHSESPEKPLEGNTCLSQMHSWAPLKVLHN----DSDILFPVSGVGSYSPADAP-LGSLENGTGPEDHVLPDPG-----LRYSVEASSPGHGSPLSSLLPSASVPESMTISELRQATVAMMNRKDELEEENRSLRNLLDGEMEHSAALRQEVDTLKRKVAEQEERQGMKVQALARENEVLKVQLKKYVGAVQMLKREG-QTAE-VPNLWSVDGEVTVAEQKPGEIAEELASSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNIYRRYTEFRSLHHKLQNKYPQVRAYNFPPKKAIGNKDAKFVEERRKQLQNYLRSVMNKVIQMVPEFAASPKKETLIQLMPFFVDITPPGEPVN--SRPKAASRFPKLSRGQPRETRNVEPQSGDL", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "Q9D3S3-1", "uniprot_id": "SNX29_MOUSE", "id": "Q9D3S3-1", "name": "Sorting nexin-29", "aln": "MSGSQNDD-RRQFLLERLLDAVKQCQIRFGGRKEIASDSDSRVTCLCAQFEAVLQHGMKRSRGLALTAAAIKQAAGFTSKTETEPVFWVYVKEVLNKHELQRFYSLHHITSDAGRGRAWLRCALNEHSLERYLHMLLADRARLSTFYEDWSFVMDEERSSMLPTMAAGLNSILFAINIDNKDLNGQSKFAPTVSDLLKESTQNVTSLLKESTQGMSSLLREITASSAVS--ILIKPEQETDPLPVISKNVHVDTRCKRERRRRKKVTNIVSFDDDEEEQGTGDTLKKMPGTAESSEENSDRSSVNIMAAFEGTFGPNSNGSQSS--SSWKIDSASLNGELGYQKLDVKSIDD-DVDENEEDAYRSPLGRGHTGHAESPDRTLDGNACLAQVHGWAPLQVLHGDADADTDVLFPVSGVGSYGAADAP-VGSLENGTGTENHIIPEPG-----LRY-REASSPGQGSPLSSLLPSASVPESMTVHELRQAIVAMMNRKDELEEENGSLRNLLDGEMEHSAALRQEVDALRRKVTEQQERHATKVQALARENEVLKVQLKKYVGAVQMLKREG-QTAEAVPSLWNVDAEVTVPEQKPGEVAEELASSYERKLIEVAEMHGELIEFNERLHRALVAKEALVSQMRQELIDLRGPVPGDLSQTSEDQSLSDFEISNRALINVWIPSVFLRGKAANAFHVYQVYIRIKDDEWNVYRRYTEFRALHHQLQSAFPQVRAYSFPPKKAIGNKDAKFVEERRKQLQSYLRSVMNKVIQMVPEFAANPKKETLVQLVPFFVDITPPGEPLNKSSRPKAVSRFPKLSRGHPREVRNVEPQSGDL", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0ACD6B5D4-1", "uniprot_id": "A0ACD6B5D4_DANRE", "id": "A0ACD6B5D4-1", "name": "", "aln": "MNGAQQNDLKRQNLLERLLDAVKQCQIRFGGRKEIASDSDSRVICLCAQFEAVLQHGLRKSRGLALTAAAIKHVAGFSSKTEAELTFWFYVKDHLNRHELQRFYSLRNITSEQGRGRAWLRCALNEHSLERYLHMLLADRARLSAFYEDWAFVLDEERASMLPTMAAGLNSILFAINIDNTDLNGQVRGGSSVSHLLKESTQGMSSLWKESTQGVSTLLREIGTATAVVPGFIPRSDAPSDPLPVLPRSTSADSGLRKERRRKKKITNIISFDDDLDAG-----AEDEDEAGEDVVRSLRKSAVGHVSSEEALDPPHSTSPVHNGLTEPGIVSWAETPPQNGLLPDTKSIDN--EEEDEDDIYRKNRPELPEEDHGNGETMIVG--SLSSVSMWSPRQIITENDNDNSHILIPLPPSEPYTQQAASSVENVEFHGQKESSSPPTDSEKQSQLQFSMEPDLPAQVEPVISVPPTPGLPESMTVAELRQAIVAMMNRKDELTEQNTSLRGLLDGEMEHSAGLRQEVDGLKKRLAELEERHAAKVQALMRENEVLKVQLKKYVGAVQMLKREGSQGGDALTNQRNCEGLPPAPQSRSMADIEELASNYERKLIEVAEMHGELIEFNERLYRSLMAKDNLIAQMRQELIDLRGPIPGDLSQTSDDPSLSDFETTQRALVNVWIPSVFLQGRAANAYHVYQVYIRILDNEWNVYRRYAEFRTLHNYLRPQFPQVDTFNFPPKKAIGNKDAKFVEERRKQLQSYLRMVMNKLIQTLPEFTAQPTKETLLQFLPFCQDSPTANESGAKTARSKASSRFPRLGRNSARESRNPEPQSGDL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": "*.*:*::* :** ****************************** *************:::************:.***:****:* .** ***: **:*********::*:*: ***************************.***:*****:**:****:*********************.***** : ..:**.*******.::** ******:*:*:*** :::** :: :.: :*****:.:.. .*: ::**:::**:***:****: : :. :.*. . :*:*. ::: *. *:*... . .. * * : . . *.****: :*:*:* * . . . . : : * .*:.: *:* ::: ::.:*:*:. .* *. : .:* *. * . *:: *.. *.: .*: *: *:..:*****: ***** ********** *:* ***.**********.****** *:::::* :**:. ***** ************************ * .: :.. . :. ...:.:. *****.**********************:*:*:**: *::************:********:* ****** ::***:*********:*:****:********* *:***:****:***:**: *: :*** ::.***********************.*** ****:** :***:*.*.****:*::** * ....*. :*.** ****:*.*. .** ** *******", "identical_positions": 472, "similar_positions": 202, "identity": "56.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121105-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q9NS82-1", "uniprot_id": "AAA1_HUMAN", "id": "Q9NS82-1", "name": "Asc-type amino acid transporter 1", "aln": "------MAGHTQQPSGRGNPRPAPSPSPVPGTVPGASERVALKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPTTASRVLSMACLMLLTWVNSSSVRWATRIQDMFTGGKLLALSLIIGVGLLQIFQGHFEELRPSNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEEMVDARKNLPRAIFISIPLVTFVYTFTNIAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTYSRLCFSGAREGHLPSLLAMIHVRHCTPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLLLRWRRPALHRPIKVNLLIPVAYLVFWAFLLVFSFISEPMVCGVGVIIILTGVPIFFLGVFWRSKPKCVHRLTESMTHWGQELCFVVYPQDAPEEEENGPCP-PSLLPATDKPSKPQ", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P63115-1", "uniprot_id": "AAA1_MOUSE", "id": "P63115-1", "name": "Asc-type amino acid transporter 1", "aln": "MRRDSDMASHIQQPGGHGNPGPAPSPSPGPGPGPGASERVALKKEIGLVSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSLCYAELGVAIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYVLQPVFPNCIPPATASRVLSMACLMLLTWVNSSSVRWATRIQVIFTGGKLLALSLIITVGFVQIFQGHFEELRPTNAFAFWMTPSVGHLALAFLQGSFAFSGWNFLNYVTEELVDPRKNLPRAIFISIPLVTFVYTFTNVAYFTAMSPQELLSSNAVAVTFGEKLLGYFSWVMPVSVALSTFGGINGYLFTSSRLCFSGAREGHLPSFLAMIHVRRCTPIPALLVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLVLRWRRPALHRPIKVNLLVPVVYLVFWAFLLVFSFISEPMVCGVGIIIILTGVPIFFLGVFWRSKPKCVHRFTESMTRWGQELCFVVYPQGSLEEEENGPMGQPSPLPITDKPLKTQ", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7FE11-1", "uniprot_id": "E7FE11_DANRE", "id": "E7FE11-1", "name": "", "aln": "------MDGVERK---KTEARRSIMKDSELKRDSGIPERVTLKKEIGLLSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALVVWMLGGGVAALGSLCYAELGVTIPKSGGDYSYVTEIFGGLVGFLLLWSAVLIMYPTTLAVIALTFSSYVLQPVFPHCVPPYIATRMLSAICILFLTWVNCYSVRLATRIQDAFTVGKLLALGLIITVGLVQICGGNYESLTPQTAFTFNKAPSIGQIALAFLHASFAFSGWNFLNYVTEEVVDPRRNLPRAIYISIPLVTCVYTLTNIAYFSSMSPEELLSSNAVAVTFGEKLLGMFSTLMPISVALSTFGGINGYLFTSSRLCFSGAREGHLPSLLAMIHFKHCTPIPALLVCCTATIVILCIGETHNLINYVSFINYLSYGVTIAGLLYYRWKKPNLYRPIKVSLLVPVCYLLFWALLLAFSLHSEPLVCGVGLVIMLTGVPVYFLGVYWKDKPRCIYDFTEWATYLGQRVFFVVFPQIDPIELAEWTDK----SSFTSKSSGHL", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * . :: : :. : .. .* .***:*******:*********************************.**:*****:************:********:*********.***************:****::***.********:*:** *:*:** *:::*****. *** ***** ** ******.*** **::** *::*.* * .**:* :**:*::*****:.****************:**.*:******:******* ***:**:***::***:****************** ** :**:**************** ***************:*****.::*********** ** **: :*:*:.***********.***** *** **::* *:*****.**:** **:***:**.**: ***:*****::*:*****::****:*:.**:*:: :** * **.: ***:** * : . . *.*. ", "identical_positions": 356, "similar_positions": 96, "identity": "67.17%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121105-3", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q8BLB8-1", "uniprot_id": "AN34C_MOUSE", "id": "Q8BLB8-1", "name": "Ankyrin repeat domain-containing protein 34C", "aln": "MMDDDTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALKHLLDACKAKGKEVIIITTDKSSSGTKTTKQYLNVPPSPKVEDRQSPPLCTTPSDVELKTSGLASPPSEKDDDFFILQTGHQSGCSTS-KVLNEPGSPTRKVSSLKRARLPQLKRLQSEPWGLIAPSVLAAATRQDETHGTSTDNEVIRSINDVTFPKRGPLSRTNSIDSKDPTLFPTVQEQVLKVSAS--TPASWKAAYEKGQAPHPRLARRGTLPLDQEKSGMCPPGPSTLKDPASLKLLENDLYDLDIQPVGDPPNSMSLESGKGPLDRKKLNSSHLSLFHGSRESLEVVPSTS-PTSVRRRPPHLLERRGSGTLLLDRIAHTRPGFLPPLNVNLNPPIPDIRASSKPASPLASGLKSMAPVAPNSPKRVDLRSKKKLLRRHSMQIEQMKQLSDFEEIMA--", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P0C6C1-1", "uniprot_id": "AN34C_HUMAN", "id": "P0C6C1-1", "name": "Ankyrin repeat domain-containing protein 34C", "aln": "MMDDDTELRTDGNSLLKAVWLGRLRLTRLLLEGGAYINESNDKGETALMVACITKHVDQQSISKSKMVKYLLDNRADPNIQDKSGKTALIHACIRRAGGEVVSLLLENGADPSLEDRTGASALVYAINADDKDALKHLLDACKAKGKEVIIITTDKSSSGTKTTKQYLNVPPSPKVEDRHSPPLCASPSDIELKALGLDSPLTEKEDDFFSLQAGHPSSCNTS-KAVNEPGSPTRKVSNLKRARLPQLKRLQSEPWGLIAPSVLAASTRQDETHGASTDNEVIKSISDISFPKRGPLSRTNSIDSKDPTLFHTVTEQVLKIPVSS-APASWKAAYEKGQAPHPRLARRGTLPVDQEKCGMGPSGPSALKEPASLKWLENDLYDLDIQPGPDPPNSISLESGKGPLDRKKLNSSHLSLFHGSRESLDTVPSTS-PSSARRRPPHLLERRGSGTLLLDRISHTRPGFLPPLNVNLNPPIPDIRSSSKPSCSLASGLKSMVPVAPSSPKRVDLRSKKKLLRRHSMQIEQMKQLSDFEEIMT--", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "F1QC31-1", "uniprot_id": "F1QC31_DANRE", "id": "F1QC31-1", "name": "", "aln": "-MADVLELRTDGNSLLKAVWLRRLRLTRLLLEGGAYINESNDRGETPLMVACMSKHSDQQSVSKAKLVKYLLDNKADPNIQDKAGRSALMHACSHRAGHEVVSLLLTNGADPSLEDRHGSSALVYAVNADDKETLKVLLDACKAKGKEVIIITTDKSPSGTKTTKQYLNVPPSPELDERATPAPCASPSEIDLHASPSPSKEEEK-DTVFNFQTKFKSTSSTAAKLPNGLTSPSKKPANPKRARLPQLKRLQSEPWGLIAPSVLAAAN--EESKRANSDEDVVAGVNGLSLSRRGTLSRHNSVDGKD-ILFPMMGDQNTKISPTSSLPPSSKASYERSLAQHQPLARRSTVPTEQEASGVN-FGPASLRDTVHRRRLGTEHYDSDSQLYSD---SSMLDSPKAPLERRKLNTSPLAMLTGSRESLDSNPSTSSPSTARCRAPGLLERRGSGTLLLDYISHTRPGHLPPLNVNPNPPIPDIGASSKPSSPLAAGIRLIAPVAPNSPKRGNLRTKKKLVRRHSMQVEQMKQLSNFEELNHQS", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " * * *************** ********************:***.*****::** ****:**:*:*******:********:*::**:*** :*** ******* ********** *:******:*****::** ********************.****************::::* :*. *::**:::*:: * ** * .* :*: . * ..*: * * **::* :. **************************:. :*:: :.:*::*: .:..:::.:**.*** **:*.** ** : :* *:. : *.* **:**:. * * ****.*:* :** .*: **::*::.. : * .: ** * * * * *:* *.**:*:***:* *::: ******: **** *::.* *.* ************* *:*****.******* ******* :****:..**:*:: :.****.**** :**:****:******:*******:***: ", "identical_positions": 329, "similar_positions": 119, "identity": "60.93%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121105-5", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "P51556-1", "uniprot_id": "DGKA_RAT", "id": "P51556-1", "name": "Diacylglycerol kinase alpha", "aln": "----MAKDK----GLISPEDFAQLQKYIDYSTKSVSDVLKVF------EMNKYCQGDEIGYLGFEQFLKMYLEVEEVPHHLCWTLFWSFHSSQ----------------------DLDEETESKANVICLS--------------------------------------------------------------------------------------------------------------------------------------------------DVYCYFTLLEGGSPEDKLEFTFKLYDMDRNGILDSTEVEKIILQMMRVAEYLDWDVSELRPILQEMMKEMDRDGSGCVSLAEWVRAGATTVPLLVLLGID-MTMKDDGHHIWRPKRFSRPVYCNLCE-LSIGLGKQGLSCNLCKYIVHDHCAMKAQPCEVSTYAKSRKD--IGVQPHVWVRGGCHSGRCDRCQKKIRTYHSLTGLHCVWCHLEIHDDCLQAVGPECDCGLLRDHILPPCSIYPRVLVSGQECK-----QKTTDVTSLCTPEAFRIEPVSNTHPLLVFINPKSGGKQGQSVLWKFQYILNPRQVFN-LKDGPEPGLRFFKDVPQFRVLVCGGDGTVGWILETIDKANFPIVPPVAVLPLGTGNDLARCLRWGRGYEGENLRKILKDIEISKVVYLDRWLLEVIPQQNGEKSDP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPSQIINNYFSIGVDASIAHRFHLMREKYPEKFNSRMKNKLWYLEFATSESIFSTCKKLEESVTVEICGKLLDLSD-LSLEGIAVLNIPSMHGGSNLWGDTK---------RPHGDTCGINQALGSVAKIITDPDILKTCVPDMSDKRLEVVGIEGVIEMGQIYTRLKSAGHRLAKCSEITFQTTKTLPMQVDGEPWMQAPCTIKITHKNQMPMLMGP-APSSSNFFGFWS-", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "O88673-1", "uniprot_id": "DGKA_MOUSE", "id": "O88673-1", "name": "Diacylglycerol kinase alpha", "aln": "----MAKEK----GLISPEDFAQLQKYIEYSTKRVSDVLKVFDD--G-EMNRFCQGDAIGYLGFEQFMKMYLEMEEVPHHLCWALFWSFHTSQ----------------------VAAEKTKSKANVICLS--------------------------------------------------------------------------------------------------------------------------------------------------DVYCYFTLLEGGRPEDKLEFTFKLYDMDRNGILDSTEVEKIILQMMRVAEYLDWDVSELRPILQEMMREMDQDGSGSVSLDEWVRAGATTVPLLVLLGMD-VTMKDDGNHIWRPKRFTRLVYCNLCE-QSISLGKQGLSCNFCKYIVHDHCAMKAQPCEVSTYAKSRKD--IGVQSHLWVRGGCHSGRCDRCQKKIRTYHSLTGLHCVWCHLEIHDDCLQAVGPECDCGLLRDHILPPCSIYPSVLVSGQECK-----HKTTDDTSLCTPEAFRIEPVSNTHPLLVFINLKSGGKQGQSVLWKFQYILNPRQVFD-LKDGPEPGLRFFKDVPQFRILVCGGDGTVGWVLETIDKANFATVPPVAVLPLGTGNDLARCLRWGRGYEGENLRKILKDIELSKVVYLDRWFLEVIPQQNGEKSDP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPSQIINNYFSIGVDASIAHRFHLMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESVTVEICGKLLDLSD-LSLEGIAVLNIPSTHGGSNLWGDTK---------RPHGDTCEINQALGSAAKIITDPDILKTCVPDMSDKRLEVVGIEGAIEMGQIYTRLKSAGHRLAKCSEITFQTTKTLPMQIDGEPWMQAPCTIKITHKNQMPMLMGP-PSNSYNFFGFWS-", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "P23743-1", "uniprot_id": "DGKA_HUMAN", "id": "P23743-1", "name": "Diacylglycerol kinase alpha", "aln": "----MAKER----GLISPSDFAQLQKYMEYSTKKVSDVLKLFED--G-EMAKYVQGDAIGYEGFQQFLKIYLEVDNVPRHLSLALFQSFETGH----------------------CLNETNVTKD-VVCLN--------------------------------------------------------------------------------------------------------------------------------------------------DVSCYFSLLEGGRPEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYDGSGSVSQAEWVRAGATTVPLLVLLGLE-MTLKDDGQHMWRPKRFPRPVYCNLCE-SSIGLGKQGLSCNLCKYTVHDQCAMKALPCEVSTYAKSRKD--IGVQSHVWVRGGCESGRCDRCQKKIRIYHSLTGLHCVWCHLEIHDDCLQAVGHECDCGLLRDHILPPSSIYPSVLASGPDRKNSKTSQKTMDDLNLSTSEALRIDPVPNTHPLLVFVNPKSGGKQGQRVLWKFQYILNPRQVFNLLKDGPEIGLRLFKDVPDSRILVCGGDGTVGWILETIDKANLPVLPPVAVLPLGTGNDLARCLRWGGGYEGQNLAKILKDLEMSKVVHMDRWSVEVIPQQTEEKSDP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPFQIINNYFSIGVDASIAHRFHIMREKYPEKFNSRMKNKLWYFEFATSESIFSTCKKLEESLTVEICGKPLDLSN-LSLEGIAVLNIPSMHGGSNLWGDTR---------RPHGDIYGINQALGATAKVITDPDILKTCVPDLSDKRLEVVGLEGAIEMGQIYTKLKNAGRRLAKCSEITFHTTKTLPMQIDGEPWMQTPCTIKITHKNQMPMLMGP-PPRSTNFFGFLS-", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB13A3N9-1", "uniprot_id": "A0AB13A3N9_DANRE", "id": "A0AB13A3N9-1", "name": "Diacylglycerol kinase", "aln": "----MADAESALENEINPVDFIQLQEYIEYSRITAKDAMKEFHA--GGKLVHHRFGDHTDAAGFALFLSSYLEVEDFPADLCRRLFGYFQRCEQ--------------------SCVDPRLHTKDGGVSLK--------------------------------------------------------------------------------------------------------------------------------------------------AVSCYFSILEDGNPRDKLEYTFKLYDKDDNGLLDSKEVDKIVAQMMKAAEYLGWDVTELKPVLEDMLKAMDVDSSGAVTLEEWINGGLNNIPLLVLLGLK-VADKD-GQHVWRLKNFNRPTYCFVCQNMMLGLRKQGLSCNFCKYTVHSSCANKNHTPCVRTFVRSKAE--IGCSAHDWISADCESNKCQICHKKIKI---LTGQRCAWCHSMRHTDCVPLGSSHCDCGSLQHHILPPWAICAVDQADCISVSG---LGETHLGNITSEGHFLQIFPVMDTNPLLVFVNPKSGGKQGKRVLRKFQYLLNPRQVYNLDNGGPNPGLQFFQNLQAFRVLVCGGDGTVGWVLDAIDKANMAIRPPVAILPLGTGNDLARCLNWGGGYEGTDLTEILKQIEESRSIQMDRWSLRVAPVDDADEGDP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VPNDIINNYFSIGVDASIAHQFHVMREKHPQKFNSRARNKLWYFQLATSETISASCRNLKDCLSIECCGVPVDLSR-LSLEGVAVLNIPSMHGGSNLWGETK---------SAE--------KPKTWQEVRVDPEALQTCSQDMSDELLEVVGLESVLEMGQIYTGLKSKAHRLAQAAHITVRTCKTLPMQVDGEPWMQPPCTIHITHKNQANMLTAP-AAKSVGCLFK---", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q01583-4", "uniprot_id": "DGK1_DROME", "id": "Q01583-4", "name": "Diacylglycerol kinase 1", "aln": "MNIGIAAPK---WDKLSPREFLQLQELASYSTRKLQDVLREFSSPSAASTPKCIPDGDIDFDGFRRFLDAFLDCEA-PLDLAKHLFVSFLKPNVTQAQLHGRALNQMAAISSTAACAPVTSHTKGSIPNINSIAELMPQCSGGGGGIGGTGGVAGAEGHAQARSSFVDKIHGITDKLHHSLGGHLSHDPSKTGSVHPMLTVTPSPLASGPSMFQASNPARRSVDSSPSHSATNHSQMSRNSSKKSSNSVNCKIDADIKLLARKLSHFDPLTLKVPLKDVVCYLSLLEAGRPEDKLEFMFRLYDTDSNGVLDTAEMDAIVNQMMAVAEYLGWDVSELRPILQEMMVEIDYDADGTVSLDEWQRGGMTTIPLLVLLGVDSTTLKEDGIHVWRLKHFSKPAYCNLCLNMLVGLGKKGLCCVLCKYTVHERCVQHAPASCITTYVKSKKPKCGGDLLHHWVEGNCYG-RCSKCRKRIKAYHGITGLTCRWCHMMLHNRCASSVKKECTLGEYSELIVPPTAICPAVLDRQRSVN---QAHKKSQMHHHQATHFQITPPDELSCPLLVFVNPKSGGRQGDRILRKFQYMLNPRQVYDLSKGGPKEGLTLFKDLPRFRVICCGGDGTVGWVLEAMDSIELASQPAIGVIPLGTGNDLARCLRWGGGYEGENIPKLMDKFRRASTVMLDRWSIEVTNTPHSDDMRPKVTLHSNMQKVIELSQSVVVDKSLMERFEEIQRQSKQVATSMGTAASSTSIMMASKTETEMETMATMEFGSSTTTTNRTTTTKSISMSTFETQCLQQTLRTAMSSSSSNTSSGSPCNGNQDAETEVDSHAAAAADVREKSVPRRSGETEKQSLETLLLQHKQQMQQQQQQQQQGVTSLAVEEAATATPVGSNQSDNSSQRNKQNNILKQQITLSLDLSDHEDEPKDDGGGAGDGTKSNGNSIPATPATPITPTTPNAASSVLQQQQQQHLQFEQQQKPIKVQSDKDCTVPYNIINNYFSVGVDAAICVKFHLEREKNPHKFNSRMKNKLWYFEYATSETFAASCKNLHESIEIVCDGVALDLANGPHLQGVALLNIPYTHGGSNLWGEHLSQKRIRKSAGPFGKSKKLRAGDKEFSATSFNSVDLSVAIQDFGDRLIEVIGLENCLHMGQVRTGLRASGRRLAQCSEVIIKTKKTFPMQIDGEPWMQMPCTIKVTHKNQVPMLMAPRSEKGRGFFNLLCS", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :* . . :.* :* ***: .** .*.:: * . : .. . ** *:. :*: : * .*. ** * . :* :. * **:::** * *.****: *:*** * **:**: *:: *: *** .****.***:**:*:*::*: :* *..* *: ** ..* ..:*******:. : *: * *:** *.* : .** :* :.* *:**.* :*** **. *. : . : *:.:*: * * *: ..* . :*. *:*:*: :** * *** * * .* * . *:** :* . . . :. . * : *****:* ****:**. :* ****:******:: :.**: ** :*::: *:: *********:*:::*. ::. *.:.::************.** **** :: :::..:. : : :*** :.* :. * ** :*******:****:*. :**: *** *.***** :*****:: ****:: ::*::*.:.: : * :**: *:*:*:**** ********: . :. *... *:.*. :**:*:*. :.***: * *: .:***:.:.: .:* **:***:******* ****::***** ** .* . . . : ", "identical_positions": 275, "similar_positions": 208, "identity": "22.56%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121105-7", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q5XIX0-1", "uniprot_id": "DJC14_RAT", "id": "Q5XIX0-1", "name": "DnaJ homolog subfamily C member 14", "aln": "--------------------------------------------------------------------------------------------------------------------------------------MAQKHPGERGLCGVHHSGGSSLITSGSSVDPEILSFSGLRDSKETAPNGTRCLKEHSDPKCTQPPNP--------------------------------------AHWSDPSHGPPRGPGPPREGGYPDESETCSEE-SGVDQELSRENETGYQEDGSPSFLPIPSACNCQGSPGVPEGT--------------CSEEGDGSSSSFCHHCTSPALGEDEELEEEYDDEEPLKFPSDFSRVSSGKKPPSRRQRHRFLTKEDVRDSGRRDPKAPGRHRLARKRSQTDKRRGLGLWGVEELCQLGQAGFWWLIELLVLVGEYVETCGYLIYACRK----LKGSDLDLFRIWVGVWARRLGGWARVMFQFLSQSFFSVAGLFIRLLR---VVGAFLLLALALFLGCLQLGWRFLVGLGDRLGWRGKAAWLFSWLDSPALHHFLTLLKD------------------------------------SRPWQQLVRVIQWGWLELPWVKQRTQRQGTAHVASGR-----------------------YCQPEEEVARLLTMAGVPED------------ELNPFHVLGVEATASDIELKKAYRQLAVMVHPDKNHHPRAEEAFKVLRAAWDIVSNPERRKEYEM---KRMAENELSRSVNEFLSKLQDDLKEAMNTMMCSRCQGKHRRFEMDREPKSARYCAECNR----------------LHPAEEGDFWAESSMLGLKITYFALMDGKVYDITEWAGCQRVGISPDTHRVPYHISFG------SRVPGTSGRQRATPES----PPADLQDFLSRIFQVPPGPMS---NGNFFAAPHPGPGTTSTSRPNSSVPKGEAKPKRRKKVRRPFQR------------------------------------------------------", "tax_id": 10116, "tax_name": "Rat" }, { "uniprot_ac": "Q921R4-1", "uniprot_id": "DJC14_MOUSE", "id": "Q921R4-1", "name": "DnaJ homolog subfamily C member 14", "aln": "--------------------------------------------------------------------------------------------------------------------------------------MAQKHPGERRLCGAHRSGGTSLSTSGSSVDPEILSFSGLRDSAETAPNGTRCLKEHSGPKYTQPPNP--------------------------------------AHWSDPSHGPPRGPGPPRGGGYPDESETGSEE-SGVDQELSRENETGYQEDGSPSFLSIPSACNCQGSPGVPEGT--------------YSEEGDGSSSSLCHHCTSPALGEDEELEEEYDDEEPLKFPSDFSRVSSGKKPLSRRQKHRFLIKEDVRDSGRREPKAPGRHRLARKRSQTDKRRGLGLWGVEELCQLGQAGFWWLIELLVLVGEYVETCGHLIYACRK----LKGSDLDLFRVWVGVWARRLGGWARMMFQFLSQSFFCVVGLLIRILR---VVGAFLLLALALFLGCLQLGWRFSVGLGNRLGWRDKTAWLFSWLGSPALHHCLTLLKD------------------------------------SRPWQQLVRLIQWGWQELPWVKQRTKKQGNAPVASGR-----------------------YCQPEEEVTRLLTMAGVPED------------ELNPFHVLGVEATASDTELKKAYRQLAVMVHPDKNHHPRAEEAFKILRAAWDIVSNPERRKEYEM---KRMAENELSRSVNEFLSKLQDDLKEAMNTMMCSRCQGKHRRFEMDREPKSARYCAECNR----------------LHPAEEGDFWAESSMLGLKITYFALMDGKVYDITEWAGCQRVGISPDTHRVPYHISFG------SRVPGTSGRQRATPES----PPADLQDFLSRIFQVPPGPMS---NGNFFAAPHPGPGTTSTSRPNSSVPKGEAKPKRRKKVRRPFQR------------------------------------------------------", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "Q6Y2X3-1", "uniprot_id": "DJC14_HUMAN", "id": "Q6Y2X3-1", "name": "DnaJ homolog subfamily C member 14", "aln": "--------------------------------------------------------------------------------------------------------------------------------------MAQKHPGERGLYGAHHSGGASLRTLGPSVDPEIPSFSGLRDSAGTAPNGTRCLTEHSGPKHTQHPNP--------------------------------------AHWLDPSHGPPGGPGPPRDAEDPDQSETSSEEESGVDQELSKENETGNQKDGN-SFLSIPSACNCQGTPGIPEGP--------------YSEGGNGSSSNFCHHCTSPALGEDE-LEEEYDDEESLKFPSDFSRVSSGKKPPSRRQRHRFPTKEDTREGGRRDPRSPGRHRLGRKRSQADKRKGLGLWGAEELCQLGQAGFWWLIELLVLVGEYVETCGHLIYACRQ----LKSSDLDLFRVWMGVWTGRLGGWAQVMFQFLSQGFYCGVGLFTRFLK---LLGALLLLALALFLGFLQLGWRFLVGLGDRLGWRDKATWLFSWLDSPALQRCLTLLRD------------------------------------SRPWQRLVRIVQWGWLELPWVKQNINRQGNAPVASGR-----------------------YCQPEEEVARLLTMAGVPED------------ELNPFHVLGVEATASDVELKKAYRQLAVMVHPDKNHHPRAEEAFKVLRAAWDIVSNAEKRKEYEM---KRMAENELSRSVNEFLSKLQDDLKEAMNTMMCSRCQGKHRRFEMDREPKSARYCAECNR----------------LHPAEEGDFWAESSMLGLKITYFALMDGKVYDITEWAGCQRVGISPDTHRVPYHISFG------SRIPGTRGRQRATPDA----PPADLQDFLSRIFQVPPGQMP---NGNFFAAPQPAPGAAAASKPNSTVPKGEAKPKRRKKVRRPFQR------------------------------------------------------", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "A0AB32TX49-1", "uniprot_id": "A0AB32TX49_DANRE", "id": "A0AB32TX49-1", "name": "", "aln": "--------------------------------------------------------------------------------------------------------------------------------------------MFRYLSKMEADMAVHWDTVEENTDRETPSVSLASSYLENDTHHGPFECEHEAMDDFDCEFP--------------------------------------DEDFDLDENEEQNAKTEDLIDNQAEDEEKSDE-------LRDEGETKSRNAGS-------------GRKGKSKK--------------------SGLGTGFYDQTQS------------------------WTSSSSSSMP-----HKSFLASSRHKQVRRRNHHLHNHSRVRRKNGIP-----LVMVCRDFLSDFVSP---WCISCIHMFVELIISLTHRCGLLVE----SSGIALYDFGTQMLSKVTDIPGLTQDMRRIVDWSRCWTVALIDGIVRSTCKARNSLLSTLGFVRVALSAGSQMMKCVVGRLAGERGRKWWLAFQSSRIWRKVSDLCVR------------------------------------IRGWR------------FKRGAGSENSNPESPNRGAE-----------------------KWQPGEELQRLLALAKIPEE------------ELDPFNVLGVDVHATESELKRAYRQLAVQVHPDKNKHPGAGEAFKVLRAAWDIVSNPETRREYEL---KRMAATELSKSMNEFLTKLQDDLKEAMNTMMCTKCEGALRWTESPARLDSVLNVINGTVPRRETCGPSPACWDCALHSSHSWTEKSLTSLSGQAVSGSASLQTHTECRITSPSALKVAVGPAATDHPQITQQAGVLQQTCRISSTASSRLALPVTRLQTEDSSLQETLLITAPDPPLELLPCFQDLLLSRAFSAPGLSVAMLANTGLKEQNLHAAARKCANRSSAEMRRKTHRCSGVCVFAHERTTPGDRLLIQCWCFSSFLMMKPQHGDSQRSEQRSAG", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "Q9VN28-1", "uniprot_id": "Q9VN28_DROME", "id": "Q9VN28-1", "name": "J domain-containing protein", "aln": "MATRQDDEIGGGSTESAPFRVLPHTDEVGNYLAHQQQQQQQQQHQHQTQNYLIHQQQHGQAPVPLMWPPPPPHLAGPPFAPHLQQQQPHMYNEYLFNLSYSGQPGQPETYSVLPVGPGNFLKVYHCPDNQVSEAGTPLFTHINMASINHHQLQHQHQAAPPTPSQPTPLYELFATNPLTLPHAQQQDAQHRQPQQTQTQAPTVSQVNHSSSSANLLINNLVNNWSPNLTGGSYIQFDGEANEMDVVLETSIAQQPQVPNQNLQQPEPLSQS-VNTLPAASKPAKSLKMPLATATVSPTAINKSSVAVPGQPEGKKRIVAEVKPMPMSYSDVLSKGTKPSAAGRDMRADNGGDYSVQSQRRPEKEDAYGNREMRTSKRSPLHDAKETGSFVPGVGHAHASRGKKRSKVSQTAPLKVQQSQSLAQPNLQPQIKSNKLNNPEKKRPLQPKNVNSNAPKFSEHKTTPVSANSSLQNHSNVLNFTPATNSSTSSRKSGSNKINSNASHSNHTGANTHAGSSSSSSSVNYSSNNNVSSSSAKRYSSSNLNPNNSSGYSYSSKRNRSNAYSSTNSPTHANSFSSNRNYELAKRIIHTWWIYTLKLLTWLFYLVYDIVVLGFSMGYERITLAYVAALAYARQLQKELKQNSGKPSIWWRSYWRRFDARFAKNSRLAVWRLFYKRKPPETTSEQFKTGRLPQTGEEAMYSLLNCKGKDAYSILGVPPDSSQEQIRKHYKKIAVLVHPDKNKQAGAEEAFKVLQRAFELIGEPENRLIYDQSIAETLHTEKAWTELHDLLSQLQTKMAEAANTIRCSTCAQRHPRKLTERPHYAARECASCKIR----------------HSAKDGDIWAETSMMGLRWKYLALMDGKVYDITEWANCQKGALS-HLEPNSHMVQYR-------IVRGAQQQQQQQQQQ-----QQQQQQQHHQHPQQPHHDRGVHHPGGGVSGVSEATLHEFLDNLYSGQHPGAHNAFAGNARRRTRRN------------------------------------------------------", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " . . . : . . . . .: :* . : * . * . : * *:. :: .. . * .: .* .. : *. . * . * . : * . : .: .. :. : : : . : * . . :. : . . . :. . .: . . :: .: : : :. : : . :* * . : . :*: :.: :*** ::: :::: *:::** ******::. * ****:*: *::::.:.* * *: : : : .::::*::** .: ** **: *: * :. . . *.:.. : :*: * . * :: :. ... : .:. . . : .: : . *: * . .: .. : :. : .*. . ", "identical_positions": 53, "similar_positions": 163, "identity": "5.03%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121106-2", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "A1A5B4-1", "uniprot_id": "ANO9_HUMAN", "id": "A1A5B4-1", "name": "Anoctamin-9", "aln": "---MQGEESLRILVEPEGDSFPLMEISTCETEASEQWDYVLVAQRHTQRDPRQARQQ-QFLEELRRKGFHIKVIRDQKQVFFGIRADNSVFGLYRTLLLEPEGPAPHAELAAPTTIPVTTSLRIRIVNFVVMNNKTSAGETFEDLMKDGVFEARFPLH--KGEGRLKKTWARWRHMFR--EQPVDEIRNYFGEKVALYFVWLGWYTYMLVPAALTGLLVFLSGFSLFEASQISKEICEAHDILMCPLGDHSRRYQRLSETCTFAKLTHLFDNDGTVVFAIFMALWATVFLEIWKRQRARVVLHWDLYVWDEEQEEMALQLINCPDYKLRPYQHSYLRSTVILVLTLLMICLMIGMAHVLVVYRVLASALFSSSAVPFLEEQVTTAVVVTGALVHYVTIIIMTKINRCVALKLCDFEMPRTFSERESRFTIRFFTLQFFTHFSSLIYIAFILGRINGHPGKSTRLAGLWKLEECHASGCMMDLFVQMAIIMGLKQTLSNCVEYLVPWVTHKCRSLRASESGHLP----------RDP--------ELRDWRRNYLLNPVNTFSLFDEFMEMMIQYGFTTIFVAAFPLAPLLALFSNLVEIRLDAIKMVWLQRRLVPRKAKDIGTWLQVLETIGVLAVIANGMVIAFTSEFIPRVVYKYRYSPCLKEGNSTVDCLKGYVNHSLSVFHTKDFQDPDG-----IEGSENVTLCRYRDYRNPPDYNFSEQFWFLLAIRLAFVILFEHVALCIKLIAAWFVPDIPQSVKNKVLEVKYQRLREKMWHGRQRLGGVGAGSRPPMPAHPTPASIFSARSTDV", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P86044-1", "uniprot_id": "ANO9_MOUSE", "id": "P86044-1", "name": "Anoctamin-9", "aln": "---MQDDESSQIFMGPEGDQLPLVEMGSCKPEASDQWDCVLVADLQTLKIQKHAQKQLQFLENLESNGFHFKMLKDQKKVFFGIRADSDVIDKYRTLLMNPEDSGSRDEQSFN-----IATTRIRIVSFVVNN-KLKPGDTFEDLVKDGVFETMFLLH--KGEQNLKNIWARWRNMFE--PQPIDEIREYFGEKVALYFTWLGWYTYMLVPAAVVGLIVFLSGFALFDSSQISKEICSANDIFMCPLGDHSHRYLRLSEMCTFAKLTHLFDNEGTVLFAIFMALWATVFLEIWKRKRAHEVQSWKLYEWDEEEEEMALELINSPHYKLKDHRHSYLSSTIILILSLFMICLMIGMAHVLVVYRVLAGALFSS----LVKQQVTTAVVVTGAVVHYIIIVIMTKVNKYVALKLCKFEESGTFSEQERKFTVKFFILQFFAHFSSLIYIAFILGRINGHPGKSTRLAGLWKLEECHLSGCMMDLFIQMAIIMGLKQTLSNCVEYLCPLLAHKWRLMWASKHGHMS----------KDP--------ELKEWQRNYYMNPINTFSLFDEFMEMMIQYGFTTIFVAAFPLAPLLALFSNLVEIRLDAIKMVRLQRRLVPRKAKDIGTWLQVLETIGVLAVIANGMVIAFTSEFIPRVVYKYHYGPCRTNRTFTDDCLTNYVNHSLSVFYTKHFNDHSR-----MEGQENVTVCRYRDYRNEHDYNLSEQFWFILAIRLTFVILFEHFALCIKLIAAWFVPDVPQKVKNEVLQEKYDRIRHRMR--------------------------FSSRSTDV", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "E7F503-1", "uniprot_id": "E7F503_DANRE", "id": "E7F503-1", "name": "Anoctamin", "aln": "MMYFKDDEEGVPLQEVDNGNEPLLPT-QHNTYVPRLYDYVLVANKVEDMEDQLFKKQDAFILELKRKNIRVTRVENDGKLFFGVRAPEEIFTKYKYLLKVSDGCNWSAEESRESS--VSFCTRIRIVHFVLNNTFIGSGEGLQDLLRQGAFETMFCLHEKKEQKKLKKKWASWYSVLRLFQQPVTDVKDYFGEKVALYYLWLGWYTRMLVPAAVIGIVVFLYGLAFFNTSPLIHEVCDS-DIIMCPRCDIKCKAWNLSDTCIYAKVSQLFDNEGTVAFAMFMAIWATLFFEVWKRHRSLYVSKWNVFDWCDDEEELILEIVNDPQCKPKEYRHSYLRSTLVLLLVTLVLVVIIGLTQALVIFRVLTSILLSKSQWHLLREHATTIAMLFGAVLHYITIQVMTRVNKFVALKLCEIEETRSFAATERSFTVKMFSFQFFTLFSSLFYVAFFLGRINGYPGNYVRIAGEWRLEECHPSGCLTDLFIQMAVILVLKQTINNIFEFTVPWLKMLFKRSKTKKKSRKCGNCYRKACREKDGNIEQCDLCKLRDWMTNYDLSDVNAFSLFNEFLEMVLQFSFTTIFVAAFPLAPLLALINNIFEIRLDAIKMVSLERRLVPKKTNDIGVWNKILEVVGVMAVIANGLVIGISSDFIPRLAYRYRYGPCAVNNNSGLDCMTGYINNTLATAFMSNMNVKKDFQELITEGGHNVTQCSYKDYRSNEDQSLTSQFWFILALRFAFVILFEHVVVICKFIAAWFIPDNPNRVKNHRLDDKLRRLKKELMEAS---------------------TLYDTTSTVV", "tax_id": 7955, "tax_name": "Zebrafish" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " ::.:*. : :... **: :. .. :* ****: : ::* *: :*. :.::.. :.:: ::***:** ..:: *: ** .:. * : ***** **: * .*: ::**:::*.**: * ** * : .**: ** * ::. **: ::::*********: ****** ******: *::*** *:::*::* : :*:*.: **:*** * . : .**: * :**:::****:*** **:***:***:*:*:***:*: * *.:: * :::**: *:::* *. * : ::**** **::*:* ::: ::**:::.**::***:. *:*. ::.::.** .:: **::**: * :**::*: ******.:* . :*: * **:::* :***: ****:*:**:******:**: .*:** *:***** ***: ***:***:*: ****:.* .*: * : : :.: .: :* :*::* ** :. :*:****:**:**::*:.*****************:.*:.********** *:*****:*::***.* ::**.:**:******:**.::*:****:.*:*:*.** : . **:..*:*::*:. . ..:: . ** .*** * *:***. * .::.****:**:*::*******..: *:*****:** *: ***. *: * *::..: :.: ** *", "identical_positions": 323, "similar_positions": 259, "identity": "39.73%" }, { "cls_id": "homologset.agr.ZFIN:ZDB-GENE-121107-1", "date": "2026-09-09 05:52:11 EDT-0400", "sequences": [ { "uniprot_ac": "Q99767-1", "uniprot_id": "APBA2_HUMAN", "id": "Q99767-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------MAHRKLESVGSGMLDHR--------------------------------------------------VRPGPVPHS-------------QEPESEDMELPLEGYVP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EGLELAALRPESPAPEEQECHN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HSPDGDSSSDYVNNTSEEE------------------------------------------------------------------DYDEG--LPEEEEGITYYIRYCPEDDSYLEGMDCNG----------------EEYLAHSAHP-------------------------------------------------------VDTDECQEAVEEWTDSAG--------------------PHPH------------------------------------GHEAEGSQDYPDGQLPIPE-------------------DEPSVLEAHDQEED-----------GHYCASKE----GYQDYYPEEANG---------------------------------------------------------NTG-ASPYR--------------LRRGDGDLEDQEEDIDQIVAEIKMSLS-------------------MTSITSASEASPEHGPE------PGP-------------EDSVEACPPIKASCSPSRHEARP------------------------------------KSLNLLPEAKHPGDP---------------------QRG-FKPKTR-TPEERLKWPHEQVCNGLEQPRKQQRSDLN--------------GPVDNNNIPETKK----VASFPSFVAVPGPCEPED----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSEGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPR---------SASQDCIETTPGAQEG---------KKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLS-QKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI", "tax_id": 9606, "tax_name": "Human" }, { "uniprot_ac": "P98084-1", "uniprot_id": "APBA2_MOUSE", "id": "P98084-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 2", "aln": "-----------------------------------------------------------------------------------------------------------------------------MAHRKRQSTASSMLDHR--------------------------------------------------ARPGPIPHD-------------QEPESEDTELPLESYVP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TGLELGTLRPESPTPEEQECHN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HSPDGDSSSDYVNNTSEEE------------------------------------------------------------------DYDEG--LPEEEEGVTYYIRYCPEDDSYLEGMDCNG----------------EEYIAHGAHP-------------------------------------------------------VDTDECQEAVEDWTDSVG--------------------PHTH------------------------------------SHGAENSQEYPDGHLPIPE-------------------DDPTVLEVHDQEED-----------GHYCSSKE----SYQDYYPPETNG---------------------------------------------------------NTGGASPYR--------------MRRGDGDLEEQEEDIDQIVAEIKMSLS-------------------MTSITSASEASPEHMPE------LDP-------------GDSTEACPPSDTGHGPGRQEARP------------------------------------KSLNLPPEVKHPGDL---------------------QRG-LKTKTR-TPEERPKWPQEQVCNGLEQPRKQQRSDLN--------------GPTDNNNIPETKK----VASFPSFVAVPGPCEAED----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSEGDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPR---------SASQDCIETTPGAQEG---------KKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLS-QKEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI", "tax_id": 10090, "tax_name": "Mouse" }, { "uniprot_ac": "A0A8M9PZ33-1", "uniprot_id": "A0A8M9PZ33_DANRE", "id": "A0A8M9PZ33-1", "name": "Amyloid-beta A4 precursor protein-binding family A member 3", "aln": "-----------------------------------------------------------------------------------------------------------------------------MAFKRRPETRSVAAELNP-------------------------------------------------PAFSAVPEGREQLSGDRDDPVLEEAEHDKLDCQTPSPTP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AQYSLSDESGDDSIRGESPLQP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DSMEEDSLSEYDNVGSGDEQ------------------------------------------------------------EEVERDYEEDEELQTEADRMTYYVHCCPEDESYMEGLDCHEGADG------AECPSTSQDVRESCKPK-----------EAWEHSDTSLCKGQQKDAATMVYKQPEPITETTFVQAPMAEDEEDEEETEEDVEEEDSEEEDNGGFFHYEGNEAELNNNEIPHKDNCSNVCRREGKSPPQEFSRVKV--------------GQESRRSQDNPKYSRDVPLGSNCTQRDRMERVRDKNGSDCPKVSNAPVARESRKDSRQNFKYRGHHLETKNNRETAYQGHSAVTIKG---------------------------------------------------------KSADAEDRGTWKKRHLLKYSREDARGGDGNNSHKRSKSPENCKNRPQDHP-------------------ICSHKSNGENERKISGN------VEAR------------IENEVKTKLIIAPNNSGRTKVAPDQ---------------------------------AKNVKGAPESPRASSA---------------------SSGKRNSKPRGQANTPVQSPAKQVNKDSAKPVEEEKTRPNEEQVSQSASQDSSTGPPSGQNRPQTQR----NPSFPSFVDIPGPCEPED----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LINGIIFAANYLGSTQLLSDRNPSKSVRMKQAQEAVDCVK------------AVEVETQSLTEIDLFISTKAIKVLNADTQETMMDNALRTISYIADIGNVVVLMARRRLS----------NSSLDCTESGLNSDAN---------HKQYRMICYVFESEDAQLIAQSIGQAFSMAYQEFLRANGINPKDLS-QKDYSDILNTQEMYNDDLVHFSNSDNCKQLHLEKQKGEILGVVIVESGWGSILPTVILACMLNNGPAARSGKLNVGDQIMAVNDTSLVGLPLAACQGIIKALKNHVQVKLSVVSCPPVTTVLIKRPDLQYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVAMAHEKIVHALSVSVGEINMKTMPAVMFRLLTGQETPVYM", "tax_id": 7955, "tax_name": "Zebrafish" }, { "uniprot_ac": "X2JE74-1", "uniprot_id": "X2JE74_DROME", "id": "X2JE74-1", "name": "", "aln": "--------------------------------------------------------------------MNSNSCSDSSNE---------------------SMVNPP-----HIQMNFG-----QQAQQQQSHQHQQQQQQQ--------ERYVWEMRTRS-----------------------------PNVTPASTVLN------------SPDLNGELSYVPLQGLSP---------------------------------------------------------------------------------SGGGVQGSGSYGSNAGRDS----------------------------------------------------------------------------------GSYYYQR-------------PQLHQIRLGRSPGS-----------------------QFETRDVLPQGLASP--------------GSPTDVGKADG----------------------------------------QCLRDGEIVVFDDIDTNWMNKASSGQR---------------------------------PGSNEDVLKVT----------------KMIGQLP------------------------------------IAEYEGSPRRFGSQPNTNTITMGGPRK-----------------------RP------------------------------------------------------------------------PGFPQRVSP------------------------------------TTSVANN----------------ATAAAKASVGNLIDLVDHEEE-------------------------------------RSG------------------TLREKTPTFDYLYEFSETRKVLEEFFKANPEDEKRYTDYTTESG----------------DDVASSQPQE-----------------YPATPMEQAYIGQRLARIPK-----DELYMVHR----SPTKKPPSDQNPSTAYQEHN-------DIELYIDSNSRSSGD-------LADTELEANLRRHS----------------RNFTLSPETTDYDSNCGDLDSLSNDIN-----CPTDFGKLYTS-MPVLEDG--------LSSGHASDTENNVSVVCDKQQSSQSQP---------VHEHNGNG--------ERLENDYNVMSAS----LATLTTDAS------QSALISDFASLPMP-------PAPPPSSPPQIEIADASES--MTMVPDADNPLDSHYGA----------VYAAALGGTHTEKSAGSGLGVTPVTAGGSLPS--------QAASEIQEAMKEIRSALQRAKTQ----------------------------------PEKLKFCDEVLPTD---PDSPVWVPR------------KGTTISTAQGAAADEEPDTDLETDRLLGQQRHDEQDFFADQSLADNN-ANEGTDIASNGHLNGTSDNNNPNPMNNSKPQTYSTATIR--QGIGTSLTP---NSPDICQIVG-------------------------------------------TTDISISSPEKLQFTKSPTGSIKSLKDSAN-------------------------------------------------------------------SDKKAKSRNKEGLLEPK---------VLIEGVLFRARYLGSTQLVCEGQPTKSTRMMQAEEAVSRIK----------ALAPEGESQPSTEVDLFISTEKIMVLNTDLKEIMMDHALRTISYIADIGDLVVLMARRRFVPNSVVDPSITSPLGDVPTPGIGEEESPPKEPLSKHNRTPKMICHVFESDEAQFIAQSIGQAFQVAYMEFLKANGIENESLAKEMDYQEVLNSQEIFGDELEIFAKKELQKEVVVPKAKGEILGVVIVESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLIAINGMSLVGLPLSTCQSYIRNAKNQTAVKFTVVPCPPVVEVKILRPKALFQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINNQSVVAVPHDTIVKLLSSSVGEILMKTMPTSMFRLLTGQETPIYI", "tax_id": 7227, "tax_name": "Fruit fly" }, { "uniprot_ac": "Q9W2S5-1", "uniprot_id": "Q9W2S5_DROME", "id": "Q9W2S5-1", "name": "", "aln": "MVSTTLTTLAAGQTTSSSNHHHHHHHSHQQQQQQQQQDQSQQQPHQQLPYQQRGYYALNGSLELDCDTSNTNSSSSSNNIGYQQHQQQQQQQQQPPLILSQALLSPSPPLNDQISLLFPKCRPKQQQQQQQQQQQQQQQQQQQLQPAQQHQQHVHPTDVNSSCNSNRSSSPTTAGAVGEPLASVSVSPPPPKATPTSSTPSYYKSVNIITQSPPPHSASSHSSESLSSVTPRISTNPFLCAPLTPPTPPHHHHHHHHQQQHQQKQQQPKQQHQTQQQEQQEEDTTGESVVEHSRSGAAGEVLEYPASFYYHTVGDSRRGPGSYTEMPRKRSSALPASNRQQQLHNGNGSQNPFIKENYWEAPPTRASLLLHSPTEYSEEPQQQQQIQQQQQQQQQQQQQQQQQQQQHLHASARRAYHQQREQVYGINQRPQQQQQQNILRVGRSPVNRSFPQQHQQQQQQQQQQQQQQQQQQQPHQQIPTARSNPCADGLTPLASHYLYGSKSSLDQHPGDWEPREQRKLRLREEREREREREREREREREREHLLLEQQQQLQLQEVQVARDNHLSHLAGQQQQQQQRKRHVYGEERERERDRERDMDRDHRLVNGNADPNESWQHLRVTTETLAEEGGKHGKPADKAQHQMHNTNQSQNSDVNVYREHQLDAWKLERSYTLAVESRHGIIEYEGSPRRIGVTTTSNLGATGAAAASAAADESEPPAAAEGAAAATATSQPQQQVPMATVPPLSSTATSLQKTAARAALAALAQSHPHSSHNILSTLLPHSPNPVNPGQMHAAQQSIQNYPVRPGFPQRIISPPSRDPRSSSPPLQQQQYQQQQQQQLQHQQQHFASLMSSHSNNNSNTNKQPLSSDNNAEDTSNDVSEIGTISDLTTPEAVGLSIGIAAGEMASRASTPPQTAQAPPTAVAGSTANGTGSGNGTATGNATAAGSGLGPLSLHTKSSTFDYLYEFSETRKVLEEFFKCPSTDEQPIMENGSDVDSIDIQYEFHSNFERDEEDLAEEEEAEDDEEVDDDADEENDEAEDEDEPLEQDRDQNYRAQAPPQSGHIDSERLVYSGYGQQPQLQAQLTAQPMSGARRHYSGSPLMRDFDFFLDSTSRSSGERDADQDGLNHNQLLSTSSGHGGGVGVSGGLGVGPGGGHNYRYSPETTDYDSNCGDLDSLSGEMNGGVSTSCSNYAKFYASAMPVLEDG--------LSSGHTSDTENNNNNQKNLQQSTVNQGGQCPTSLSGSTSIGGSGGISMLMDMKRISTNHSLNSMNNQTTTASTTTDSNGGVGGVGHHLVATLVASPNNEQAKSQCQTQLQSHPPKTLSLDQSPSNHSKVFKNIDPELDSLYSIGVFHRPDTVQMTPPPPAPAPHRKPNNNGCSSGVVNTNGSLAGGSNDVDLLQPSSKHTPLAAAISSTLQRSSPTSTITGNGIGNGSGKTRSAGSNCSSSANGGMPPPIPERTNLVSAVQRSPSPGPNSPVWLSRHLDGGAGKDLLESGSDNHSKNHSADEEDVDTDLETDRLLGHQRLDDQGYYDENKSWDRKPRSLLSKISPKQQIPSTKTRNGYNALLSSTPELPPPIPPKGQSGLGLGLTLGAGNGGKLLDLVGGMVQRSLSRSSSEHSEKSLSKMPISGGDLCAGGVDVVASTVAATSATVVASTPALGSPGNGGGSERSAAEMANPGGAVKLSEQEIGTINGGSVMPLGSGSGTGSGAGSGAGSGTGTNAAVVANSNANNNVGGGGGGGNNSSGSGAGSNSNSGEKKVKKSKSKEGGAVLIEGVLFRAKYLGSTQLVCEGQPTKSTRMMQAEEAVSRIK----------ALAPDGDVQPSTEVDLFISTEKIMVLNTDLKEIMMDHALRTISYIADIGDLVVLMARRRFVP---------QDIDDAPKP----------------NRTPKMICHVFESDEAQFIAQSIGQAFQVAYMEFLKANGIEDHRFVKEMDYQEVLNSQEIFGDELEIFAKKELQKEVVVPKAKGEILGVVIVESGWGSMLPTVVIANLMSSGAAARCGQLNIGDQLIAINGLSLVGLPLSTCQTYIKNTKNQTVVKFTVVPCAPVVEVKIKRPETKYQLGFSVQNGVICSLLRGGIAERGGVRVGHRIIEINNQSVVAVPHEKIVNLLATSVGEILMKTMPTSMFRLLTGQENPIYI", "tax_id": 7227, "tax_name": "Fruit fly" } ], "algorithm": { "name": "clustalw2", "url": "http://www.clustal.org/clustal2/", "parameter": "Default Clustalw2 parameters" }, "consensus": " :: . : . . . . . . * : . . : : . . : : :: : . : :.: . *:. . : : : : . . : * : .. . .:. ** ::: : . : . . . . : . : . . : . . . : : . * . . . . :. . : ::: : *. . * . . **:*::* *.*******:.: :*:*. ** **:***. :* : : *. **:******: * ***:* :* ***:************::********: . * . :: :***:****::**:*********.:** ***:****: . : : :*.:::*:**::.*:* *::.: *:: : * ********:*******:****::* ::..*.***.*:*.:***::::*. *******::** *: **:. **:.:*.*.**. * * **. :*********:****:********************.***** .*:.**: *: ***** *****: *********.*:*:", "identical_positions": 220, "similar_positions": 183, "identity": "10.08%" } ]